Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nCPM" "RNA single nuclei brain specificity" "RNA single nuclei brain distribution" "RNA single nuclei brain specificity score" "RNA single nuclei brain specific nCPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific pTPM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA tissue cell type enrichment" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "Secretome function" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Brain expression cluster" "Cell line expression cluster" "Single cell expression cluster" Interactions "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)" "Cancer prognostics - Breast Invasive Carcinoma (TCGA)" "Cancer prognostics - Breast Invasive Carcinoma (validation)" "Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)" "Cancer prognostics - Colon Adenocarcinoma (TCGA)" "Cancer prognostics - Colon Adenocarcinoma (validation)" "Cancer prognostics - Glioblastoma Multiforme (TCGA)" "Cancer prognostics - Glioblastoma Multiforme (validation)" "Cancer prognostics - Head and Neck Squamous Cell Carcinoma (TCGA)" "Cancer prognostics - Kidney Chromophobe (TCGA)" "Cancer prognostics - Kidney Renal Clear Cell Carcinoma (TCGA)" "Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)" "Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)" "Cancer prognostics - Liver Hepatocellular Carcinoma (TCGA)" "Cancer prognostics - Liver Hepatocellular Carcinoma (validation)" "Cancer prognostics - Lung Adenocarcinoma (TCGA)" "Cancer prognostics - Lung Adenocarcinoma (validation)" "Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)" "Cancer prognostics - Lung Squamous Cell Carcinoma (validation)" "Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)" "Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)" "Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)" "Cancer prognostics - Pancreatic Adenocarcinoma (validation)" "Cancer prognostics - Prostate Adenocarcinoma (TCGA)" "Cancer prognostics - Rectum Adenocarcinoma (TCGA)" "Cancer prognostics - Rectum Adenocarcinoma (validation)" "Cancer prognostics - Skin Cutaneous Melanoma (TCGA)" "Cancer prognostics - Stomach Adenocarcinoma (TCGA)" "Cancer prognostics - Testicular Germ Cell Tumor (TCGA)" "Cancer prognostics - Thyroid Carcinoma (TCGA)" "Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)" A1BG ENSG00000121410 "Alpha-1-B glycoprotein" P04217 19 58345178-58353492 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 736 "liver: 565.1" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 7.3;Brain inhibitory neurons: 4.6;Choroid plexus epithelial cells: 3.4;Ependymal cells: 16.5;Loop of henle epithelial cells: 3.6;Microglia: 4.9;Oligodendrocytes: 22.5;Other brain neurons: 5.5;Podocytes: 7.7;Renal collecting duct intercalated cells: 3.0;Renal collecting duct principal cells: 3.6" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in single" 962 "Liver Hepatocellular Carcinoma (TCGA): 695.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Breast glandular cells, Breast - Breast glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB016673, HPA044252" Supported "Secreted to blood" "No annotated function" NA NA 200000000000 88000000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 17: Choroid plexus - Cilium" "Cluster 18: Liver cancer - Metabolism" "Cluster 80: Oligodendrocytes - Myelination" 4 "CAB016673: , HPA044252: " "unprognostic (7.87e-2)" "unprognostic (1.36e-3)" "potential prognostic favorable (3.17e-4)" "unprognostic (2.33e-2)" "unprognostic (8.10e-2)" A1CF "ACF, ACF64, ACF65, APOBEC1CF, ASP" ENSG00000148584 "APOBEC1 complementation factor" Q9NQ94 10 50799409-50885675 "Predicted intracellular proteins" "mRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 143.1" "Cell type enhanced" "Detected in some" "Cholangiocytes: 254.2;Colonocytes: 141.7;Enteric transient amplifying cells: 73.3;Enterocytes: 259.2;Goblet cells: 135.0;Hepatocytes: 814.9;Neuroendocrine cells: 262.4;Pancreatic acinar cells: 88.3;Pancreatic islet cells: 160.3;Proximal tubule cells: 74.9" "Cell type enriched" "Detected in some" 6 "cerebellar inhibitory: 7.4" "Cancer enriched" "Detected in many" 5 "Liver Hepatocellular Carcinoma (TCGA): 35.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "liver cancer: 21.2" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Stomach - Gastric enteroendocrine cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA037779, HPA044079" Enhanced Supported Nucleoplasm NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 18: Liver cancer - Metabolism" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" 19 Nucleoplasm "HPA037779: , HPA044079: " "unprognostic (1.77e-1)" "unprognostic (2.54e-2)" "potential prognostic favorable (2.84e-8)" "unprognostic (7.85e-3)" "unprognostic (2.76e-2)" "unprognostic (1.71e-1)" "unprognostic (6.26e-2)" "unprognostic (2.71e-2)" "unprognostic (1.81e-1)" "unprognostic (2.99e-1)" "unprognostic (3.29e-2)" "unprognostic (4.72e-2)" A2M "CPAMD5, FWP007, S863-7" ENSG00000175899 Alpha-2-macroglobulin P01023 12 9067664-9116229 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 1683.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 371.1;Fibroblasts: 333.8;Hepatocytes: 757.8;Hofbauer cells: 412.3;Mast cells: 302.4;Microglia: 848.5;Pericytes: 656.8;Pituicytes/FSCs: 349.9;Retinal horizontal cells: 681.1;Salivary myoepithelial cells: 314.6;Vascular endothelial cells: 1019.5;Vascular smooth muscle cells: 723.8" "Group enriched" "Detected in all" 10 "central nervous system macrophage: 1008.7;endothelial cell: 1846.2;pericyte: 487.5;vascular associated smooth muscle cell: 635.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.5" "Lineage enhanced" "Detected in single" "T-cells: 1.5" "Cancer enhanced" "Detected in many" "Brain cancer: 48.1;liver cancer: 106.6;skin cancer: 72.1" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Adrenal gland - Fibroblasts, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Fibroblasts, Liver - Hepatocytes, Lung - Fibroblasts_1, Prostate - Fibroblasts, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Thyroid gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002265, CAB017621" Supported "Secreted to blood" "Enzyme inhibitor" NA NA 1630000000000 420000000000 "Cluster 1: T-cells - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 18: Liver cancer - Metabolism" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 71 "CAB017621: , HPA002265: " "unprognostic (2.07e-2)" "unprognostic (5.51e-2)" "unprognostic (2.75e-1)" "unprognostic (8.27e-3)" "unprognostic (3.84e-2)" "unprognostic (3.48e-2)" "unprognostic (2.01e-1)" "unprognostic (2.51e-2)" "unprognostic (5.26e-2)" "unprognostic (1.96e-1)" "validated prognostic favorable (2.84e-7)" "validated prognostic favorable (1.68e-4)" "unprognostic (4.02e-2)" "unprognostic (1.60e-1)" "unprognostic (3.09e-1)" "unprognostic (1.90e-3)" "unprognostic (1.86e-1)" "unprognostic (3.03e-3)" "unprognostic (2.22e-2)" "unprognostic (3.00e-1)" "unprognostic (3.98e-2)" "unprognostic (4.61e-2)" "unprognostic (7.19e-3)" "unprognostic (6.41e-2)" "unprognostic (2.11e-1)" "unprognostic (1.37e-1)" "unprognostic (3.16e-1)" "unprognostic (6.95e-3)" "unprognostic (9.29e-2)" "unprognostic (2.48e-2)" "unprognostic (3.21e-1)" A2ML1 "CPAMD9, FLJ25179, p170" ENSG00000166535 "Alpha-2-macroglobulin like 1" A8K2U0 12 8822621-8887001 "Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 188.5;esophagus: 538.3;vagina: 199.8" "Group enriched" "Detected in many" 4 "Esophageal apical cells: 4253.0;Esophageal suprabasal cells: 1299.8" "Cell type enhanced" "Detected in all" "astrocyte: 43.2;ependymal cell: 38.6" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 82.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "head and neck cancer: 13.2" "Minor Salivary Gland - Minor salivary gland basal cells, Testis - Sertoli cells" "Low region specificity" "Detected in many" "HPA038847, HPA038848" Enhanced "Secreted in other tissues" "Enzyme inhibitor" NA NA 12000000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 33 "HPA038847: , HPA038848: " "unprognostic (3.18e-2)" "unprognostic (1.02e-1)" "unprognostic (8.57e-2)" "unprognostic (1.08e-1)" "unprognostic (3.00e-1)" "unprognostic (3.53e-1)" "unprognostic (1.25e-2)" "unprognostic (2.80e-3)" "unprognostic (1.21e-3)" "unprognostic (3.36e-3)" "unprognostic (1.20e-1)" "unprognostic (2.17e-1)" "unprognostic (6.82e-2)" "validated prognostic unfavorable (8.89e-4)" "validated prognostic unfavorable (3.17e-4)" "unprognostic (4.07e-2)" "unprognostic (5.66e-2)" "unprognostic (2.07e-1)" "unprognostic (2.11e-1)" "unprognostic (2.71e-1)" A3GALT2 "A3GALT2P, IGB3S, IGBS3S" ENSG00000184389 "Alpha 1,3-galactosyltransferase 2" U3KPV4 1 33306766-33321098 "Enzymes, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 13.9;Early primary spermatocytes: 18.7;Early spermatids: 22.7;Hepatic stellate cells: 12.9;Kupffer cells: 12.3;Neutrophils: 48.7" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 37: Neurons - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 24: Neutrophils - Innate immunity signal integration" "unprognostic (3.13e-3)" A4GALT "A14GALT, Gb3S, P(k), P1" ENSG00000128274 "Alpha 1,4-galactosyltransferase (P blood group)" Q9NPC4 22 42692121-42721298 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 11.5;Endometrial secretory cells: 13.6;Loop of henle epithelial cells: 17.7;Ocular epithelial cells: 14.3;Papillary tip epithelial cells: 47.1;Podocytes: 20.9;Proximal tubule cells: 58.5;Renal collecting duct intercalated cells: 21.8;Renal collecting duct principal cells: 10.5;Renal connecting tubule cells: 33.9;Respiratory secretory cells: 10.7" "Group enriched" "Detected in some" 13 "endothelial cell: 38.0;fibroblast: 52.5;pericyte: 67.6;vascular associated smooth muscle cell: 39.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells, Pituitary gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001141 Uncertain Mitochondria NA NA 16000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 88: Proximal tubular cells - Transmembrane transport" 2 Mitochondria "HPA001141: " "unprognostic (6.58e-2)" "unprognostic (4.79e-2)" "unprognostic (4.77e-3)" "unprognostic (6.53e-2)" "unprognostic (8.54e-2)" "unprognostic (1.12e-1)" "unprognostic (1.59e-1)" "unprognostic (8.73e-2)" "unprognostic (8.49e-2)" "unprognostic (3.75e-3)" "potential prognostic favorable (2.49e-4)" "unprognostic (4.49e-3)" "unprognostic (2.83e-3)" "unprognostic (1.10e-1)" "unprognostic (2.66e-2)" "unprognostic (4.41e-3)" "unprognostic (2.37e-3)" "unprognostic (1.51e-2)" "unprognostic (4.80e-2)" "unprognostic (1.61e-1)" "unprognostic (1.50e-1)" "unprognostic (7.74e-3)" "potential prognostic unfavorable (1.86e-5)" "unprognostic (2.32e-2)" "unprognostic (3.70e-2)" "unprognostic (1.36e-2)" "unprognostic (2.91e-1)" "unprognostic (2.16e-2)" "unprognostic (7.05e-2)" "unprognostic (1.63e-2)" "unprognostic (1.57e-2)" A4GNT alpha4GnT ENSG00000118017 Alpha-1,4-N-acetylglucosaminyltransferase Q9UNA3 3 138123713-138132390 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "stomach 1: 22.3" "Group enriched" "Detected in some" 6 "Gastric chief cells: 27.3;Mucous neck cells: 50.8" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Pancreatic Adenocarcinoma (TCGA): 3.5;Stomach Adenocarcinoma (TCGA): 4.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Kidney cancer: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA008017 Enhanced "Intracellular and membrane" Enzyme NA NA "Cluster 60: Stomach - Digestion" "Cluster 3: Choroid plexus - Cilium" "Cluster 66: Non-specific - Mitochondria" "Cluster 97: Non-specific - Cellular respiration" 22 "HPA008017: " "potential prognostic favorable (2.45e-6)" "unprognostic (1.51e-1)" "unprognostic (1.35e-3)" "unprognostic (3.99e-2)" AAAS ENSG00000094914 "Aladin WD repeat nucleoporin" Q9NRG9 12 53307456-53324864 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 70.4;Oocytes: 101.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040086 Approved Supported "Nucleoplasm,Nuclear membrane,Centrosome,Cytosol,End piece" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 49: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 16 "Nuclear membrane" "Nucleoplasm, Centrosome, Cytosol, End piece" "HPA040086: " "unprognostic (6.85e-2)" "unprognostic (1.26e-2)" "unprognostic (4.77e-1)" "unprognostic (1.58e-1)" "unprognostic (2.15e-1)" "unprognostic (3.25e-2)" "unprognostic (1.81e-1)" "unprognostic (7.49e-2)" "unprognostic (2.13e-1)" "unprognostic (2.43e-3)" "potential prognostic favorable (9.31e-4)" "unprognostic (1.04e-1)" "unprognostic (2.56e-1)" "unprognostic (2.39e-3)" "unprognostic (6.98e-2)" "unprognostic (2.81e-3)" "unprognostic (3.90e-2)" "unprognostic (2.64e-1)" "unprognostic (2.45e-2)" "unprognostic (2.99e-2)" "unprognostic (9.22e-3)" "unprognostic (1.27e-1)" "unprognostic (1.67e-3)" "unprognostic (3.16e-1)" "unprognostic (6.20e-3)" "unprognostic (8.83e-2)" "unprognostic (5.15e-2)" "unprognostic (3.82e-1)" "unprognostic (1.40e-1)" "unprognostic (7.28e-2)" "unprognostic (5.75e-2)" AACS "ACSF1, FLJ12389, SUR-5" ENSG00000081760 "Acetoacetyl-CoA synthetase" Q86V21 12 125065434-125143333 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 95.6;Esophageal suprabasal cells: 95.0;Retinal ganglion cells: 170.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058815 Approved Approved Vesicles NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 58: Skin - Keratinization" "Cluster 14: Neurons - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 35: Neurons - Synaptic function & neurogenesis" 3 Vesicles "HPA058815: " "unprognostic (1.27e-2)" "unprognostic (1.52e-2)" "unprognostic (4.09e-1)" "unprognostic (1.75e-1)" "unprognostic (3.93e-2)" "unprognostic (9.36e-2)" "unprognostic (1.63e-3)" "unprognostic (3.18e-2)" "unprognostic (7.02e-2)" "potential prognostic unfavorable (1.72e-4)" "unprognostic (1.08e-2)" "unprognostic (1.29e-1)" "unprognostic (2.44e-1)" "validated prognostic unfavorable (7.57e-5)" "validated prognostic unfavorable (4.14e-4)" "unprognostic (1.59e-3)" "unprognostic (1.53e-2)" "unprognostic (5.54e-2)" "unprognostic (7.59e-2)" "unprognostic (4.59e-2)" "unprognostic (8.08e-3)" "unprognostic (2.26e-2)" "unprognostic (3.22e-2)" "unprognostic (3.50e-1)" "unprognostic (9.19e-2)" "unprognostic (2.04e-1)" "unprognostic (1.47e-1)" "unprognostic (1.64e-1)" "unprognostic (3.03e-1)" "unprognostic (3.57e-2)" "unprognostic (7.63e-2)" AADAC "CES5A1, DAC" ENSG00000114771 "Arylacetamide deacetylase" P22760 3 151814073-151828488 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "adrenal gland: 235.1;intestine: 227.7;liver: 884.4" "Group enriched" "Detected in some" 4 "Enterocytes: 457.0;Hepatocytes: 847.8;Pancreatic acinar cells: 409.7" "Cell type enhanced" "Detected in single" "ependymal cell: 1.1" "Cancer enriched" "Detected in many" 20 "Liver Hepatocellular Carcinoma (TCGA): 238.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 68.3;liver cancer: 39.2" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA002911 Approved NA NA "Cluster 76: Non-specific - Metabolism" "Cluster 7: Liver cancer - Metabolism" "Cluster 93: Hepatocytes - Bile production & excretion" 1 "HPA002911: " "unprognostic (2.38e-1)" "unprognostic (8.38e-2)" "unprognostic (1.57e-1)" "unprognostic (5.57e-2)" "unprognostic (1.29e-1)" "potential prognostic favorable (6.76e-5)" "unprognostic (1.39e-1)" "unprognostic (9.78e-3)" "unprognostic (9.76e-2)" "unprognostic (1.18e-1)" "potential prognostic favorable (1.59e-5)" "unprognostic (2.57e-1)" "potential prognostic unfavorable (1.22e-5)" "unprognostic (8.13e-2)" "unprognostic (6.41e-2)" "potential prognostic unfavorable (1.63e-4)" AADACL2 MGC72001 ENSG00000197953 "Arylacetamide deacetylase like 2" Q6P093 3 151733916-151761339 "Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 19 "skin 1: 10.1" "Group enriched" "Detected in some" 5 "Ependymal cells: 6.2;Suprabasal keratinocytes: 3.0" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 1.9;ependymal cell: 7.3;fibroblast: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells, Colon - Fibroblasts, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" Enzyme NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 34: Ciliated cells - Cilia assembly & function" AADACL3 ENSG00000188984 "Arylacetamide deacetylase like 3" Q5VUY0 1 12716110-12728760 "Predicted membrane proteins" Hydrolase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "placenta: 1.5;skin 1: 3.0" "Cell type enhanced" "Detected in some" "Early spermatids: 1.1;Extravillous trophoblasts: 4.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Bladder cancer: 2.1" "Skin - Sebaceous gland cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 37: Skin - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" AADACL4 ENSG00000204518 "Arylacetamide deacetylase like 4" Q5VUY2 1 12644085-12667076 "Predicted membrane proteins" Hydrolase "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "choroid plexus: 1.7" "Cell type enriched" "Detected in some" 6 "Podocytes: 19.6" "Cell type enhanced" "Detected in single" "choroid plexus epithelial cell: 1.2" "Not detected" "Not detected" "Region enriched" "Detected in single" 15 "choroid plexus: 1.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Sebaceous gland cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 57: Podocytes - Glomerular filtration" AADAT "KAT2, KATII, KYAT2" ENSG00000109576 "Aminoadipate aminotransferase" Q8N5Z0 4 170060222-170091699 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Aminotransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 62.7" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 31.9;Breast lactating cells: 41.1;Early primary spermatocytes: 40.7;Extravillous trophoblasts: 113.0;Hepatocytes: 42.1;Prostatic glandular cells: 27.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 48.9" "Liver - Hepatocytes, Skeletal muscle - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA037502 Enhanced Approved "Vesicles,Plasma membrane" NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 53: Neurons - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" "Plasma membrane" Vesicles "HPA037502: " "unprognostic (1.25e-1)" "unprognostic (2.12e-1)" "unprognostic (3.05e-1)" "unprognostic (2.15e-1)" "unprognostic (1.08e-2)" "unprognostic (3.09e-2)" "unprognostic (9.04e-2)" "unprognostic (1.27e-2)" "unprognostic (1.40e-1)" "unprognostic (2.72e-1)" "unprognostic (2.09e-2)" "unprognostic (7.29e-2)" "unprognostic (3.90e-3)" "unprognostic (1.43e-1)" "unprognostic (2.59e-2)" "unprognostic (1.47e-1)" "unprognostic (5.98e-2)" "unprognostic (1.22e-1)" "unprognostic (1.80e-1)" "unprognostic (6.90e-2)" "unprognostic (3.54e-1)" "unprognostic (1.98e-2)" "unprognostic (4.74e-3)" "unprognostic (2.58e-1)" "unprognostic (3.01e-3)" "unprognostic (2.20e-1)" "unprognostic (1.61e-1)" "unprognostic (3.87e-2)" "unprognostic (1.42e-1)" "unprognostic (5.27e-3)" "unprognostic (1.15e-1)" AAGAB "FLJ11506, p34" ENSG00000103591 "Alpha and gamma adaptin binding protein" Q6PD74 15 67200667-67255195 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039371, HPA040174" Supported Supported "Nuclear speckles,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 76: Non-specific - Metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" 15 "Nuclear speckles, Cytosol" "HPA039371: , HPA040174: " "unprognostic (2.02e-2)" "unprognostic (2.74e-3)" "unprognostic (2.36e-1)" "unprognostic (1.79e-2)" "unprognostic (5.08e-2)" "unprognostic (1.79e-1)" "unprognostic (3.53e-2)" "unprognostic (6.02e-2)" "unprognostic (2.35e-1)" "unprognostic (1.21e-1)" "potential prognostic favorable (2.05e-6)" "unprognostic (2.13e-1)" "unprognostic (7.66e-2)" "unprognostic (5.75e-2)" "potential prognostic unfavorable (9.14e-4)" "unprognostic (7.28e-3)" "unprognostic (1.05e-1)" "unprognostic (6.51e-2)" "unprognostic (1.66e-1)" "unprognostic (2.78e-1)" "unprognostic (8.36e-2)" "unprognostic (8.75e-2)" "unprognostic (2.69e-2)" "unprognostic (2.13e-1)" "unprognostic (5.30e-2)" "unprognostic (1.45e-1)" "unprognostic (1.00e-1)" "unprognostic (1.02e-1)" "unprognostic (5.22e-1)" "unprognostic (3.01e-3)" "unprognostic (3.47e-2)" AAK1 "DKFZp686K16132, KIAA1048" ENSG00000115977 "AP2 associated kinase 1" Q2M2I8 2 69457997-69674349 "Enzymes, Predicted intracellular proteins" Endocytosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 83.6" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017931, HPA020289" Enhanced Supported "Vesicles,Plasma membrane,Cytosol" No No "Cluster 11: T-cells - Unknown function" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" 28 "Plasma membrane" "Vesicles, Cytosol" "HPA017931: , HPA020289: " "unprognostic (1.64e-1)" "unprognostic (2.95e-3)" "unprognostic (1.48e-1)" "unprognostic (2.32e-1)" "unprognostic (2.02e-1)" "unprognostic (2.48e-3)" "unprognostic (1.07e-1)" "unprognostic (1.15e-1)" "unprognostic (4.66e-2)" "potential prognostic unfavorable (6.13e-4)" "unprognostic (6.46e-3)" "unprognostic (7.86e-2)" "unprognostic (5.57e-2)" "unprognostic (2.42e-2)" "unprognostic (8.05e-2)" "unprognostic (2.48e-1)" "unprognostic (1.53e-2)" "unprognostic (2.27e-1)" "unprognostic (9.91e-2)" "potential prognostic unfavorable (1.45e-4)" "unprognostic (1.43e-3)" "unprognostic (2.71e-1)" "potential prognostic unfavorable (9.11e-4)" "unprognostic (1.14e-1)" "unprognostic (6.14e-3)" "unprognostic (1.30e-2)" "unprognostic (5.20e-1)" "unprognostic (9.10e-2)" "unprognostic (1.11e-1)" "unprognostic (8.85e-3)" "unprognostic (6.12e-2)" AAMDC "C11orf67, CK067, FLJ21035, PTD015" ENSG00000087884 "Adipogenesis associated Mth938 domain containing" Q9H7C9 11 77821109-77918432 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 621.6" "Cell type enhanced" "Detected in all" "Myonuclei: 395.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 144.6" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA037918, HPA037919" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 24: Non-specific - Unknown function" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 7 Nucleoplasm Cytosol "HPA037918: , HPA037919: " "unprognostic (2.91e-2)" "unprognostic (2.37e-1)" "unprognostic (2.55e-1)" "unprognostic (1.99e-1)" "unprognostic (1.66e-1)" "unprognostic (6.03e-2)" "unprognostic (1.47e-2)" "unprognostic (2.28e-2)" "potential prognostic unfavorable (3.83e-4)" "unprognostic (1.64e-3)" "potential prognostic favorable (8.64e-5)" "unprognostic (2.51e-2)" "unprognostic (1.36e-1)" "unprognostic (3.62e-1)" "unprognostic (2.93e-3)" "unprognostic (1.21e-1)" "unprognostic (2.20e-1)" "unprognostic (1.40e-2)" "unprognostic (3.47e-1)" "unprognostic (5.53e-3)" "unprognostic (3.84e-3)" "unprognostic (1.15e-1)" "unprognostic (7.75e-2)" "unprognostic (2.37e-2)" "unprognostic (3.60e-1)" "unprognostic (6.03e-2)" "unprognostic (2.08e-1)" "unprognostic (8.51e-2)" "unprognostic (2.87e-1)" AAMP ENSG00000127837 "Angio associated migratory cell protein" Q13685 2 218264129-218270178 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Angiogenesis, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 190.5;Syncytiotrophoblasts: 240.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017717, HPA031868" Approved Approved "Plasma membrane,Microtubules,Cytokinetic bridge,Primary cilium,Primary cilium tip,Cytosol" Yes NA "Cluster 33: Non-specific - ATP binding" "Cluster 70: Non-specific - Protein processing" "Cluster 27: Non-specific - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 15: Non-specific - Protein processing" 23 Microtubules "Plasma membrane, Cytokinetic bridge, Primary cilium, Primary cilium tip, Cytosol" "CAB017717: , HPA031868: " "unprognostic (9.46e-2)" "unprognostic (7.23e-2)" "unprognostic (1.01e-1)" "unprognostic (4.68e-1)" "unprognostic (4.95e-2)" "unprognostic (1.07e-1)" "unprognostic (3.88e-3)" "unprognostic (6.15e-2)" "unprognostic (3.67e-2)" "unprognostic (1.25e-3)" "potential prognostic favorable (1.15e-7)" "unprognostic (5.58e-3)" "potential prognostic unfavorable (7.10e-4)" "validated prognostic unfavorable (4.27e-7)" "validated prognostic unfavorable (9.15e-8)" "unprognostic (8.83e-3)" "unprognostic (1.26e-1)" "unprognostic (8.16e-2)" "unprognostic (1.12e-1)" "unprognostic (1.05e-1)" "unprognostic (1.16e-1)" "unprognostic (3.75e-2)" "unprognostic (9.14e-2)" "unprognostic (1.69e-1)" "unprognostic (5.30e-1)" "unprognostic (9.79e-2)" "unprognostic (2.08e-1)" "unprognostic (8.84e-3)" "unprognostic (7.45e-2)" "unprognostic (2.21e-1)" "unprognostic (3.53e-2)" AANAT SNAT ENSG00000129673 "Aralkylamine N-acetyltransferase" Q16613 17 76453351-76470117 "Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Biological rhythms, Melatonin biosynthesis" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "retina: 10.2;testis: 4.5" "Group enriched" "Detected in some" 6 "Late spermatids: 50.3;Retinal bipolar cells: 175.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA054321 Supported Cytosol NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 1: Neuronal - Visual perception" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 7 Cytosol "HPA054321: " "unprognostic (3.81e-1)" "unprognostic (3.63e-2)" "unprognostic (4.56e-2)" AAR2 "bA234K24.2, C20orf4" ENSG00000131043 "AAR2 splicing factor" Q9Y312 20 36236131-36270918 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034220, HPA048645" Uncertain Approved Cytosol NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 62: Non-specific - Plasma proteins" "Cluster 17: Non-specific - RNA processing" 86 Cytosol "CAB034220: , HPA048645: " "unprognostic (2.38e-2)" "unprognostic (4.84e-2)" "unprognostic (2.46e-2)" "unprognostic (3.10e-1)" "unprognostic (3.63e-1)" "unprognostic (8.25e-2)" "unprognostic (5.37e-2)" "unprognostic (2.65e-2)" "unprognostic (2.43e-1)" "potential prognostic favorable (4.00e-6)" "unprognostic (2.98e-3)" "unprognostic (9.38e-2)" "potential prognostic unfavorable (1.15e-5)" "unprognostic (1.94e-2)" "unprognostic (9.32e-2)" "unprognostic (1.01e-1)" "unprognostic (1.34e-2)" "unprognostic (3.04e-2)" "unprognostic (7.23e-2)" "unprognostic (1.54e-1)" "unprognostic (1.40e-1)" "unprognostic (5.82e-2)" "unprognostic (3.60e-3)" "unprognostic (6.21e-2)" "unprognostic (1.21e-1)" "unprognostic (2.16e-1)" "unprognostic (1.76e-1)" "unprognostic (6.79e-2)" "unprognostic (1.88e-1)" AARD "C8orf85, LOC441376" ENSG00000205002 "Alanine and arginine rich domain containing protein" Q4LEZ3 8 116938207-116944487 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 21.1;urinary bladder: 7.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 15.8;Breast myoepithelial cells: 25.0;Breast secretory cells: 59.9;Late primary spermatocytes: 126.1;Late spermatids: 24.5;Retinal pigment epithelial cells: 21.3;Sertoli cells: 77.9;Smooth muscle cells: 39.8;Transitional alveolar cells: 19.4" "Cell type enhanced" "Detected in many" "CGE interneuron: 9.6;LAMP5-LHX6 and Chandelier: 15.0" "Cancer enriched" "Detected in many" 7 "Breast Invasive Carcinoma (TCGA): 41.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "breast cancer: 39.9;Sarcoma: 22.8" "Adipose visceral - Mesothelial cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Minor Salivary Gland - Minor salivary glandular cells, Skin - Eccrine sweat gland cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Region enriched" "Detected in some" 4 "midbrain: 5.8" HPA068290 Approved "Lipid droplets" NA NA "Cluster 47: Testis - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 13 "Lipid droplets" "HPA068290: " "unprognostic (2.57e-1)" "unprognostic (1.05e-1)" "unprognostic (1.60e-2)" "unprognostic (2.60e-2)" "unprognostic (1.36e-1)" "unprognostic (9.05e-2)" "unprognostic (3.72e-2)" "unprognostic (3.51e-1)" "unprognostic (1.02e-3)" "unprognostic (6.21e-2)" "unprognostic (3.44e-2)" "unprognostic (5.59e-2)" AARS1 "AARS, AlaRS, CMT2N" ENSG00000090861 "Alanyl-tRNA synthetase 1" P49588 16 70251983-70289707 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase, RNA-binding, tRNA-binding" "Charcot-Marie-Tooth disease, Disease variant, Epilepsy, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034261, HPA040870, HPA044223" Supported Supported Cytosol NA NA 930000 "Cluster 33: Non-specific - ATP binding" "Cluster 70: Non-specific - Protein processing" "Cluster 45: Non-specific - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 65: Non-specific - Cell growth & division" 5 Cytosol "CAB034261: , HPA040870: , HPA044223: " "unprognostic (2.04e-3)" "potential prognostic unfavorable (7.91e-4)" "unprognostic (3.62e-2)" "unprognostic (2.46e-1)" "unprognostic (6.65e-3)" "unprognostic (1.10e-1)" "unprognostic (3.71e-2)" "unprognostic (2.16e-2)" "unprognostic (2.48e-1)" "potential prognostic favorable (9.29e-6)" "unprognostic (9.49e-2)" "unprognostic (1.20e-1)" "unprognostic (9.40e-3)" "unprognostic (1.83e-1)" "unprognostic (2.62e-3)" "unprognostic (7.71e-2)" "unprognostic (1.49e-1)" "unprognostic (1.57e-1)" "unprognostic (3.64e-1)" "unprognostic (1.63e-1)" "unprognostic (7.35e-2)" "unprognostic (1.82e-1)" "unprognostic (1.26e-1)" "unprognostic (1.15e-1)" "unprognostic (1.24e-1)" "unprognostic (1.63e-1)" "unprognostic (6.24e-2)" "unprognostic (4.67e-2)" "unprognostic (4.11e-2)" AARS2 "AARSL, bA444E17.1, KIAA1270" ENSG00000124608 "Alanyl-tRNA synthetase 2, mitochondrial" Q5JTZ9 6 44298731-44313347 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase, RNA-binding, tRNA-binding" "Cancer-related genes, Cardiomyopathy, Disease variant, Neurodegeneration, Premature ovarian failure, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035636, HPA061396" Approved Enhanced Mitochondria NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 65: Non-specific - Cell growth & division" 35 Mitochondria "HPA035636: , HPA061396: " "unprognostic (8.88e-2)" "unprognostic (1.58e-1)" "unprognostic (1.61e-1)" "unprognostic (3.58e-2)" "unprognostic (1.92e-1)" "unprognostic (2.40e-1)" "unprognostic (1.59e-1)" "unprognostic (1.65e-2)" "unprognostic (3.71e-1)" "unprognostic (1.46e-2)" "unprognostic (3.84e-2)" "unprognostic (9.86e-2)" "unprognostic (3.36e-2)" "potential prognostic unfavorable (3.77e-4)" "unprognostic (3.29e-1)" "unprognostic (9.05e-2)" "unprognostic (2.36e-2)" "unprognostic (2.09e-1)" "unprognostic (7.51e-2)" "unprognostic (3.64e-1)" "unprognostic (4.27e-1)" "unprognostic (3.75e-2)" "unprognostic (3.30e-2)" "unprognostic (4.91e-2)" "unprognostic (4.69e-2)" "unprognostic (4.10e-1)" "unprognostic (1.06e-2)" "unprognostic (1.49e-1)" "unprognostic (2.62e-1)" "unprognostic (3.81e-2)" "unprognostic (6.77e-2)" AARSD1 "AlaXp, MGC2744" ENSG00000266967 "Alanyl-tRNA synthetase domain containing 1" Q9BTE6 17 42950526-42964498 "Predicted intracellular proteins" "Protein biosynthesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 7 "Astrocytes: 18.3;Bergmann glia: 18.1;Brain excitatory neurons: 26.6;Brain inhibitory neurons: 29.5;Choroid plexus epithelial cells: 19.9;Ependymal cells: 14.2;Microglia: 14.5;Oligodendrocyte progenitor cells: 18.0;Oligodendrocytes: 14.4;Other brain neurons: 27.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021408, HPA022869, HPA023714" Supported Approved "Nuclear membrane,Cytosol" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 22: Non-specific - Basic cellular functions" 7 "Nuclear membrane, Cytosol" "HPA021408: , HPA022869: , HPA023714: " "unprognostic (3.45e-2)" "unprognostic (2.47e-1)" "unprognostic (1.19e-2)" "unprognostic (6.96e-3)" "unprognostic (8.29e-2)" "unprognostic (3.29e-1)" "unprognostic (2.18e-1)" "unprognostic (2.71e-2)" "unprognostic (2.06e-2)" "unprognostic (9.71e-2)" "validated prognostic favorable (1.17e-4)" "validated prognostic favorable (3.28e-5)" "unprognostic (1.88e-1)" "unprognostic (6.48e-3)" "potential prognostic unfavorable (1.18e-4)" "unprognostic (1.73e-2)" "unprognostic (1.36e-2)" "unprognostic (1.11e-1)" "unprognostic (3.71e-2)" "unprognostic (5.87e-2)" "unprognostic (2.31e-1)" "unprognostic (5.90e-2)" "unprognostic (9.94e-3)" "unprognostic (3.59e-2)" "unprognostic (3.09e-2)" "unprognostic (4.32e-2)" "unprognostic (2.27e-1)" "unprognostic (2.61e-2)" "unprognostic (1.84e-1)" "unprognostic (6.09e-2)" "unprognostic (1.13e-1)" AASDH "ACSF4, LYS2, NRPS998" ENSG00000157426 "Aminoadipate-semialdehyde dehydrogenase" Q4L235 4 56338287-56387508 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036472, HPA036473" Approved NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 7: Non-specific - Transcription" "HPA036472: , HPA036473: " "unprognostic (4.69e-3)" "unprognostic (1.91e-2)" "unprognostic (1.75e-1)" "unprognostic (1.40e-1)" "unprognostic (2.28e-1)" "unprognostic (3.59e-1)" "unprognostic (2.39e-1)" "unprognostic (1.81e-2)" "unprognostic (2.96e-1)" "unprognostic (1.30e-1)" "validated prognostic favorable (2.91e-6)" "validated prognostic favorable (2.99e-4)" "unprognostic (2.28e-1)" "unprognostic (2.44e-2)" "unprognostic (5.13e-2)" "unprognostic (8.75e-2)" "unprognostic (1.61e-1)" "unprognostic (5.18e-2)" "unprognostic (1.35e-2)" "unprognostic (2.16e-1)" "unprognostic (4.12e-2)" "unprognostic (3.38e-1)" "unprognostic (5.21e-3)" "unprognostic (4.48e-1)" "unprognostic (1.00e-2)" "unprognostic (1.49e-1)" "unprognostic (6.32e-2)" "unprognostic (2.69e-1)" "unprognostic (3.78e-1)" "unprognostic (4.67e-3)" "unprognostic (3.00e-2)" AASDHPPT "AASD-PPT, ACPS, CGI-80, LYS5" ENSG00000149313 "Aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase" Q9NRN7 11 106075501-106098699 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 450.4;Late primary spermatocytes: 193.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026687 Approved NA NA "Cluster 1: T-cells - Unknown function" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 34: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 13 "HPA026687: " "unprognostic (1.39e-1)" "unprognostic (4.15e-2)" "unprognostic (3.25e-1)" "unprognostic (1.20e-1)" "unprognostic (1.12e-1)" "unprognostic (1.03e-2)" "unprognostic (6.13e-2)" "unprognostic (1.86e-2)" "unprognostic (6.19e-3)" "unprognostic (5.26e-1)" "potential prognostic favorable (1.03e-5)" "unprognostic (3.72e-2)" "unprognostic (2.54e-1)" "potential prognostic unfavorable (3.77e-4)" "unprognostic (2.87e-1)" "unprognostic (2.84e-3)" "unprognostic (1.55e-2)" "unprognostic (2.14e-1)" "unprognostic (3.63e-2)" "unprognostic (1.80e-1)" "unprognostic (2.29e-2)" "unprognostic (3.98e-1)" "unprognostic (1.15e-1)" "unprognostic (7.21e-2)" "unprognostic (7.43e-3)" "unprognostic (4.74e-2)" "unprognostic (5.80e-2)" "unprognostic (8.12e-2)" "unprognostic (2.08e-1)" "unprognostic (2.95e-1)" "unprognostic (9.30e-3)" AASS "LKRSDH, LORSDH" ENSG00000008311 "Aminoadipate-semialdehyde synthase" Q9UDR5 7 122064583-122144308 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Multifunctional enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bergmann glia: 251.3;Hepatocytes: 392.2;Ovarian stromal cells: 272.8;Schwann cells: 296.1" "Cell type enhanced" "Detected in all" "Bergmann glia: 263.2;committed oligodendrocyte precursor: 267.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 34.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020637, HPA020728, HPA020734" Enhanced Approved Nucleoplasm,Vesicles,Mitochondria Yes No 20000 "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 72: Neuronal - Signal transduction" "Cluster 103: Non-specific - Basic cellular processes" 1 Mitochondria "Nucleoplasm, Vesicles" "HPA020637: , HPA020728: , HPA020734: " "unprognostic (7.78e-2)" "unprognostic (4.81e-2)" "unprognostic (3.83e-2)" "unprognostic (3.25e-3)" "unprognostic (4.35e-2)" "unprognostic (7.18e-3)" "unprognostic (1.98e-2)" "unprognostic (8.49e-2)" "unprognostic (1.31e-1)" "unprognostic (2.73e-1)" "unprognostic (6.70e-2)" "potential prognostic favorable (9.30e-5)" "unprognostic (4.69e-2)" "potential prognostic favorable (7.41e-4)" "unprognostic (2.37e-3)" "unprognostic (1.25e-1)" "unprognostic (5.41e-2)" "unprognostic (2.42e-2)" "potential prognostic favorable (7.28e-4)" "unprognostic (2.27e-1)" "unprognostic (1.75e-1)" "unprognostic (3.23e-1)" "unprognostic (7.42e-3)" "unprognostic (2.04e-1)" "unprognostic (8.03e-2)" "unprognostic (1.62e-1)" "unprognostic (1.04e-1)" "unprognostic (1.09e-2)" "unprognostic (7.41e-2)" "unprognostic (6.34e-2)" "unprognostic (1.04e-1)" AATF "BFR2, CHE-1, CHE1, DED" ENSG00000275700 "Apoptosis antagonizing transcription factor" Q9NY61 17 36948925-37056871 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 82.4;Oocytes: 92.1;Proximal tubule cells: 88.5;Renal connecting tubule cells: 107.9;Syncytiotrophoblasts: 102.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Macrophages, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004940, HPA075963" Uncertain Supported Nucleoplasm,Nucleoli NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 54: Non-specific - Ribosome" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 102: Non-specific - Mixed function" 106 Nucleoli Nucleoplasm "HPA004940: , HPA075963: " "unprognostic (1.54e-2)" "unprognostic (9.54e-2)" "unprognostic (6.31e-2)" "unprognostic (8.09e-2)" "unprognostic (2.62e-2)" "potential prognostic unfavorable (3.87e-5)" "unprognostic (7.24e-2)" "potential prognostic unfavorable (5.40e-4)" "unprognostic (6.70e-3)" "unprognostic (8.50e-3)" "unprognostic (1.93e-3)" "unprognostic (3.23e-3)" "validated prognostic unfavorable (7.85e-4)" "validated prognostic unfavorable (3.43e-7)" "unprognostic (3.28e-3)" "potential prognostic unfavorable (9.42e-4)" "unprognostic (3.23e-1)" "unprognostic (8.72e-2)" "unprognostic (3.95e-2)" "unprognostic (2.90e-3)" "unprognostic (1.47e-1)" "unprognostic (8.04e-3)" "unprognostic (3.87e-3)" "unprognostic (1.53e-1)" "unprognostic (5.34e-2)" "unprognostic (1.08e-1)" "unprognostic (3.77e-2)" "unprognostic (3.25e-1)" AATK "AATYK, AATYK1, KIAA0641, LMR1, LMTK1, PPP1R77" ENSG00000181409 "Apoptosis associated tyrosine kinase" Q6ZMQ8 17 81110487-81166221 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 103.9" "Cell type enhanced" "Detected in many" "Epicardial cells: 152.4;Lactotrophs: 118.2;Neutrophils: 483.8;Oligodendrocytes: 412.1;Platelets: 138.6;Schwann cells: 121.5" "Group enriched" "Detected in all" 4 "committed oligodendrocyte precursor: 365.1;oligodendrocyte: 435.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 11 "neutrophil: 2.0" "Lineage enriched" "Detected in single" 11 "granulocytes: 2.0" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Pituitary gland - Lactotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009073 Approved Approved Mitochondria NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 24 Mitochondria "HPA009073: " "unprognostic (2.25e-2)" "unprognostic (4.43e-2)" "unprognostic (5.08e-2)" "unprognostic (1.56e-1)" "unprognostic (1.56e-1)" "unprognostic (2.39e-2)" "unprognostic (1.83e-1)" "unprognostic (2.03e-2)" "unprognostic (2.36e-2)" "unprognostic (1.61e-2)" "unprognostic (2.98e-1)" "unprognostic (4.99e-2)" "unprognostic (6.04e-2)" "unprognostic (9.13e-2)" "unprognostic (4.93e-2)" "unprognostic (4.05e-1)" "unprognostic (6.87e-3)" "unprognostic (1.55e-1)" "unprognostic (6.95e-2)" "unprognostic (1.79e-1)" "unprognostic (1.39e-1)" "unprognostic (1.93e-1)" "unprognostic (1.31e-3)" "unprognostic (1.41e-1)" "unprognostic (3.48e-2)" "unprognostic (1.90e-2)" ABAT "GABA-T, GABAT" ENSG00000183044 "4-aminobutyrate aminotransferase" P80404 16 8674596-8784575 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Neurotransmitter degradation" "Aminotransferase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 128.7;kidney: 124.5;liver: 323.2;pancreas: 130.4" "Cell type enhanced" "Detected in many" "Corticotrophs: 152.3;Ependymal cells: 173.2;Hepatocytes: 350.3;Retinal amacrine cells: 154.6;Somatotrophs: 227.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 88.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Pancreas - Exocrine glandular cells, Prostate - Prostate glandular cells, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041528, HPA041690" Enhanced Supported Supported Mitochondria No No 2600000 "Cluster 21: Neutrophils - Unknown function" "Cluster 36: Brain & Liver - Signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 6 Mitochondria "HPA041528: , HPA041690: " "unprognostic (5.62e-2)" "unprognostic (1.01e-1)" "unprognostic (2.16e-2)" "unprognostic (1.67e-1)" "unprognostic (1.18e-1)" "unprognostic (5.31e-3)" "unprognostic (3.90e-1)" "unprognostic (1.09e-1)" "unprognostic (3.66e-1)" "unprognostic (3.07e-1)" "potential prognostic favorable (5.11e-8)" "unprognostic (4.54e-2)" "potential prognostic favorable (2.14e-5)" "potential prognostic favorable (5.42e-4)" "unprognostic (2.22e-3)" "potential prognostic favorable (6.68e-5)" "unprognostic (7.12e-3)" "unprognostic (1.97e-1)" "unprognostic (8.41e-2)" "unprognostic (1.58e-1)" "unprognostic (7.24e-2)" "unprognostic (2.97e-2)" "unprognostic (2.55e-1)" "unprognostic (1.83e-1)" "unprognostic (3.98e-2)" "unprognostic (2.52e-1)" "unprognostic (4.48e-1)" "unprognostic (5.41e-2)" "unprognostic (7.31e-2)" "unprognostic (2.78e-1)" "unprognostic (3.88e-2)" ABCA1 "ABC1, HDLDT1, TGD" ENSG00000165029 "ATP binding cassette subfamily A member 1" O95477 9 104781006-104928155 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism, Transport" Translocase "Atherosclerosis, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 432.4;Adrenal cortex cells: 862.8;Kupffer cells: 1038.2;Macrophages: 728.9;Mast cells: 577.9;monocytes: 680.4;Neutrophils: 1571.1;Smooth muscle cells: 486.4" "Cell type enhanced" "Detected in all" "astrocyte: 485.5;fibroblast: 338.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "eosinophil: 13.1;neutrophil: 10.7" "Lineage enriched" "Detected in many" 8 "granulocytes: 13.1" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB069889, HPA075201" Approved Supported "Golgi apparatus,Plasma membrane" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 76: Non-specific - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 16 "Plasma membrane" "Golgi apparatus" "CAB069889: , HPA075201: " "unprognostic (1.04e-2)" "unprognostic (2.61e-2)" "unprognostic (9.75e-2)" "unprognostic (2.19e-1)" "unprognostic (2.28e-1)" "unprognostic (8.23e-2)" "unprognostic (7.72e-2)" "unprognostic (8.66e-2)" "unprognostic (2.61e-1)" "unprognostic (1.87e-2)" "potential prognostic favorable (4.66e-4)" "unprognostic (6.71e-3)" "unprognostic (9.94e-3)" "unprognostic (7.19e-2)" "unprognostic (1.03e-1)" "unprognostic (2.68e-1)" "unprognostic (8.55e-3)" "unprognostic (1.50e-1)" "unprognostic (1.65e-1)" "unprognostic (4.09e-3)" "potential prognostic unfavorable (1.19e-4)" "unprognostic (3.06e-1)" "unprognostic (5.37e-2)" "unprognostic (1.45e-1)" "unprognostic (1.99e-1)" "unprognostic (1.36e-2)" "unprognostic (2.73e-1)" "potential prognostic unfavorable (7.46e-4)" "unprognostic (5.47e-2)" "unprognostic (2.50e-1)" "unprognostic (1.14e-1)" ABCA10 EST698739 ENSG00000154263 "ATP binding cassette subfamily A member 10" Q8WWZ4 17 69147214-69244846 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 5 "Fibro-adipogenic progenitors: 1832.6" "Cell type enriched" "Detected in all" 5 "fibroblast: 1346.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 1.4" "Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" HPA014535 Uncertain NA NA "Cluster 75: Ovary - Mixed function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 108: Fibroblasts - ECM organization" "HPA014535: " "unprognostic (9.59e-3)" "unprognostic (2.79e-1)" "unprognostic (8.91e-2)" "unprognostic (1.82e-3)" "unprognostic (3.51e-1)" "unprognostic (1.32e-1)" ABCA12 "DKFZP434G232, ICR2B, LI2" ENSG00000144452 "ATP binding cassette subfamily A member 12" Q86UK0 2 214931542-215138626 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 5.4;skin 1: 19.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 62.2;Endometrial glandular cells: 61.3;Endometrial secretory cells: 78.1;Esophageal apical cells: 37.5;Esophageal suprabasal cells: 60.4;Ocular epithelial cells: 249.5;Respiratory deuterosomal cells: 35.2;Suprabasal keratinocytes: 208.9" "Cell type enhanced" "Detected in many" "deep-layer corticothalamic and 6b: 16.1;miscellaneous: 24.8" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 7.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 7.8" "Breast - Breast glandular cells, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "cerebral cortex: 1.4;hippocampal formation: 1.6" HPA078239 Approved "Nucleoli,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 37: Skin - Keratinization" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 27: Breast cancer - Unknown function" "Cluster 100: Stratified epithelial cells - Barrier functions" 1 "Vesicles, Plasma membrane" "Nucleoli, Cytosol" "HPA078239: " "unprognostic (7.94e-3)" "unprognostic (3.68e-2)" "unprognostic (7.94e-2)" "unprognostic (1.26e-2)" "potential prognostic favorable (2.46e-4)" "unprognostic (2.77e-1)" "unprognostic (2.03e-1)" "unprognostic (2.47e-3)" "unprognostic (1.42e-1)" "potential prognostic unfavorable (1.28e-4)" "potential prognostic unfavorable (7.60e-4)" "unprognostic (6.94e-2)" "unprognostic (8.16e-2)" "unprognostic (2.35e-1)" "unprognostic (1.07e-1)" "unprognostic (1.62e-3)" "unprognostic (4.70e-2)" "unprognostic (7.53e-2)" ABCA13 "FLJ33876, FLJ33951" ENSG00000179869 "ATP binding cassette subfamily A member 13" 7 48171458-48647497 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 15 "bone marrow: 42.1" "Cell type enriched" "Detected in many" 5 "Neutrophil progenitors: 4412.3" "Cell type enhanced" "Detected in many" "ependymal cell: 45.7;hippocampal CA4: 97.4" "Cancer enhanced" "Detected in many" "Lung Squamous Cell Carcinoma (TCGA): 9.1" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "lymphoma: 5.2" "Lung - Respiratory ciliated cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Spleen - Neutrophils_1, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA063601 Approved "Nucleoplasm,Vesicles,Centrosome,Basal body,Cytosol" NA NA "Cluster 15: Bone marrow - Innate immune response" "Cluster 29: Forebrain - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 1 "Nucleoplasm, Vesicles" "Centrosome, Basal body, Cytosol" "HPA063601: " "unprognostic (1.32e-1)" "unprognostic (4.14e-2)" "unprognostic (3.57e-2)" "unprognostic (5.96e-2)" "unprognostic (3.54e-2)" "unprognostic (5.64e-2)" "unprognostic (8.64e-2)" "unprognostic (1.53e-1)" "unprognostic (2.59e-1)" "unprognostic (1.06e-2)" "unprognostic (9.70e-2)" "unprognostic (1.92e-1)" "unprognostic (7.03e-2)" "unprognostic (3.73e-1)" ABCA2 ABC2 ENSG00000107331 "ATP binding cassette subfamily A member 2" Q9BZC7 9 137007234-137028915 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Translocase "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "brain: 178.1" "Cell type enriched" "Detected in many" 6 "Oligodendrocytes: 498.4" "Group enriched" "Detected in all" 5 "committed oligodendrocyte precursor: 255.9;oligodendrocyte: 623.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042886 Approved Supported Vesicles NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 80: Oligodendrocytes - Myelination" 1 Vesicles "HPA042886: " "unprognostic (1.67e-1)" "unprognostic (1.30e-2)" "potential prognostic favorable (3.38e-4)" "unprognostic (1.10e-1)" "unprognostic (2.67e-1)" "unprognostic (5.82e-2)" "unprognostic (2.21e-1)" "unprognostic (3.31e-1)" "unprognostic (1.04e-1)" "unprognostic (4.15e-1)" "potential prognostic favorable (1.25e-6)" "unprognostic (2.61e-2)" "unprognostic (1.79e-2)" "unprognostic (2.32e-2)" "unprognostic (1.13e-2)" "unprognostic (1.99e-1)" "unprognostic (6.86e-2)" "unprognostic (7.98e-3)" "unprognostic (4.44e-1)" "unprognostic (1.69e-1)" "unprognostic (7.60e-2)" "unprognostic (3.39e-2)" "unprognostic (5.08e-2)" "unprognostic (3.77e-2)" "unprognostic (1.42e-1)" "unprognostic (1.80e-1)" "unprognostic (1.66e-2)" "unprognostic (1.12e-3)" "unprognostic (2.02e-1)" "unprognostic (2.89e-1)" "unprognostic (9.43e-2)" ABCA3 "ABC-C, ABC3, EST111653, LBM180" ENSG00000167972 "ATP binding cassette subfamily A member 3" Q99758 16 2275881-2340746 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 38.5;lung: 86.0" "Group enriched" "Detected in many" 4 "Alveolar cells type 1: 405.5;Alveolar cells type 2: 1235.3;Transitional alveolar cells: 315.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007884, HPA008426" Enhanced Supported Nucleoplasm,Vesicles NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 24: Neurons - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 81: Alveolar cells - Lung function" 2 "Nucleoplasm, Vesicles" "HPA007884: , HPA008426: " "unprognostic (4.96e-2)" "unprognostic (2.64e-1)" "unprognostic (4.20e-1)" "unprognostic (1.12e-1)" "unprognostic (1.17e-1)" "unprognostic (4.19e-3)" "unprognostic (2.49e-1)" "unprognostic (5.78e-3)" "unprognostic (2.03e-1)" "unprognostic (1.95e-1)" "unprognostic (3.03e-3)" "unprognostic (1.16e-1)" "unprognostic (1.33e-1)" "unprognostic (2.21e-2)" "unprognostic (1.68e-2)" "unprognostic (1.00e-3)" "unprognostic (2.87e-1)" "unprognostic (6.86e-3)" "unprognostic (1.56e-1)" "unprognostic (4.20e-2)" "unprognostic (2.52e-2)" "unprognostic (5.93e-3)" "unprognostic (3.00e-1)" "unprognostic (5.76e-2)" "unprognostic (1.87e-3)" "unprognostic (1.48e-3)" "unprognostic (1.11e-2)" "unprognostic (1.56e-2)" "unprognostic (4.07e-2)" "unprognostic (4.15e-1)" "unprognostic (2.11e-2)" ABCA4 "ABCR, ARMD2, CORD3, FFM, RP19, STGD, STGD1" ENSG00000198691 "ATP binding cassette subfamily A member 4" P78363 1 93992834-94121148 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Sensory transduction, Transport, Vision" "Hydrolase, Translocase" "Age-related macular degeneration, Cone-rod dystrophy, Disease variant, Retinitis pigmentosa, Stargardt disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 31 "choroid plexus: 90.6;retina: 328.7" "Group enriched" "Detected in many" 9 "Choroid plexus epithelial cells: 828.7;Cone photoreceptor cells: 1105.4;Retinal pigment epithelial cells: 686.3;Rod photoreceptor cells: 1897.2" "Cell type enriched" "Detected in many" 6 "choroid plexus epithelial cell: 578.6" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 8.2;Lung Squamous Cell Carcinoma (TCGA): 9.2" "Region enriched" "Detected in many" 17 "choroid plexus: 313.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA064420, HPA078826" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 42: Retina - Visual perception" "Cluster 36: Choroid plexus - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" "Endoplasmic reticulum" "HPA064420: , HPA078826: " "unprognostic (1.57e-1)" "unprognostic (1.16e-1)" "unprognostic (1.68e-1)" "unprognostic (4.37e-2)" "unprognostic (1.50e-1)" "unprognostic (3.19e-1)" "unprognostic (2.40e-2)" "unprognostic (1.15e-2)" "unprognostic (7.83e-2)" "unprognostic (6.63e-3)" "unprognostic (1.62e-1)" "unprognostic (2.79e-2)" "unprognostic (1.51e-1)" "unprognostic (5.65e-3)" ABCA5 EST90625 ENSG00000154265 "ATP binding cassette subfamily A member 5" Q8WWZ7 17 69244311-69327244 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 827.6;Gonadotrophs: 717.7;Myonuclei: 917.9;Renal collecting duct intercalated cells: 494.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022032, HPA062904" Approved Approved Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 2: Neurons - Nucleosome" "Cluster 11: Neuronal - Sensory perception" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" Nucleoplasm "HPA022032: , HPA062904: " "unprognostic (5.97e-3)" "unprognostic (9.68e-2)" "unprognostic (1.08e-1)" "unprognostic (2.26e-1)" "unprognostic (9.05e-2)" "unprognostic (8.00e-3)" "unprognostic (7.59e-3)" "unprognostic (2.58e-3)" "unprognostic (1.13e-1)" "unprognostic (2.05e-2)" "potential prognostic favorable (1.79e-6)" "unprognostic (1.16e-3)" "unprognostic (3.13e-2)" "unprognostic (2.06e-2)" "unprognostic (2.87e-2)" "unprognostic (6.76e-2)" "unprognostic (8.05e-2)" "unprognostic (1.94e-2)" "unprognostic (1.68e-2)" "unprognostic (2.42e-1)" "unprognostic (5.27e-2)" "unprognostic (2.33e-2)" "unprognostic (1.49e-1)" "unprognostic (1.23e-1)" "unprognostic (4.70e-2)" "unprognostic (2.10e-1)" "unprognostic (2.67e-2)" "unprognostic (1.15e-1)" "unprognostic (1.80e-1)" "unprognostic (2.88e-1)" "unprognostic (2.53e-1)" ABCA6 EST155051 ENSG00000154262 "ATP binding cassette subfamily A member 6" Q8N139 17 69078702-69141895 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 72.9" "Cell type enhanced" "Detected in many" "Adipocytes: 168.6;Fibro-adipogenic progenitors: 1198.2;Fibroblasts: 429.1;Hepatocytes: 238.2;Leydig cells: 234.7;Macrophages: 131.0;Ovarian stromal cells: 216.5;Pituicytes/FSCs: 338.3;Schwann cells: 165.7" "Cell type enriched" "Detected in all" 4 "fibroblast: 623.5" "Cancer enriched" "Detected in many" 4 "Liver Hepatocellular Carcinoma (TCGA): 9.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 1.9;lymphoma: 3.1" "Adrenal gland - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatocytes, Pancreas - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA064878, HPA067180" Enhanced Nucleoplasm NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 30: White matter - Myelination" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" Nucleoplasm "HPA064878: , HPA067180: " "unprognostic (1.56e-2)" "unprognostic (1.56e-1)" "unprognostic (1.42e-2)" "unprognostic (5.09e-2)" "unprognostic (1.32e-2)" "unprognostic (9.31e-2)" "unprognostic (3.02e-1)" "unprognostic (8.84e-2)" "unprognostic (5.90e-3)" "potential prognostic favorable (5.26e-6)" "unprognostic (1.14e-2)" "unprognostic (1.98e-1)" "unprognostic (1.03e-1)" "unprognostic (3.16e-1)" "unprognostic (1.77e-1)" "unprognostic (1.32e-1)" "unprognostic (4.29e-2)" "potential prognostic unfavorable (1.47e-4)" ABCA7 ABCX ENSG00000064687 "ATP binding cassette subfamily A member 7" Q8IZY2 19 1039997-1065572 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Phagocytosis, Transport" Translocase "Alzheimer disease, Amyloidosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 41.5;pituitary gland: 48.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 289.8;Extravillous trophoblasts: 473.9;Retinal bipolar cells: 235.3;Rod photoreceptor cells: 380.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041564 Enhanced Supported "Golgi apparatus,Plasma membrane,Cell Junctions" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 44: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "Golgi apparatus, Plasma membrane" "Cell Junctions" "HPA041564: " "unprognostic (3.96e-2)" "unprognostic (2.00e-1)" "unprognostic (3.49e-1)" "unprognostic (5.60e-2)" "unprognostic (5.72e-3)" "unprognostic (2.86e-1)" "unprognostic (3.89e-2)" "unprognostic (1.79e-1)" "unprognostic (6.69e-2)" "unprognostic (2.19e-1)" "potential prognostic unfavorable (4.16e-6)" "unprognostic (1.28e-1)" "unprognostic (1.42e-2)" "unprognostic (1.12e-1)" "unprognostic (4.91e-2)" "unprognostic (6.63e-2)" "unprognostic (4.78e-2)" "unprognostic (1.38e-1)" "unprognostic (1.61e-1)" "unprognostic (3.22e-2)" "unprognostic (6.87e-2)" "unprognostic (7.72e-3)" "potential prognostic unfavorable (3.23e-5)" "unprognostic (3.26e-2)" "unprognostic (9.74e-3)" "unprognostic (3.68e-1)" "unprognostic (1.46e-1)" "unprognostic (3.11e-2)" "unprognostic (1.29e-1)" "unprognostic (1.47e-1)" "unprognostic (8.45e-2)" ABCA8 KIAA0822 ENSG00000141338 "ATP binding cassette subfamily A member 8" O94911 17 68867289-68955392 "Metabolic proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 265.6;Fibro-adipogenic progenitors: 1400.8;Fibroblasts: 441.1;Leydig cells: 966.6;Myosatellite cells: 457.8;Oligodendrocytes: 494.6;Pituicytes/FSCs: 397.3;Schwann cells: 443.8;Sertoli cells: 618.7;Somatotrophs: 220.6" "Group enriched" "Detected in many" 5 "fibroblast: 1081.1;oligodendrocyte: 684.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 9 "Rhabdoid: 16.0" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Pancreas - Fibroblasts, Skeletal muscle - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044914 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" Nucleoplasm Cytosol "HPA044914: " "unprognostic (2.24e-2)" "unprognostic (3.77e-3)" "unprognostic (8.80e-2)" "unprognostic (1.29e-1)" "unprognostic (3.40e-2)" "unprognostic (3.97e-1)" "potential prognostic favorable (5.80e-5)" "unprognostic (1.99e-2)" "unprognostic (3.32e-2)" "unprognostic (1.32e-2)" "potential prognostic favorable (4.16e-6)" "potential prognostic favorable (3.58e-4)" "unprognostic (5.68e-2)" "unprognostic (2.13e-1)" "unprognostic (7.01e-2)" "unprognostic (1.91e-2)" "unprognostic (3.73e-2)" "unprognostic (1.05e-1)" "unprognostic (1.99e-1)" "unprognostic (1.37e-1)" "unprognostic (1.04e-3)" "unprognostic (1.75e-1)" "unprognostic (3.01e-1)" ABCA9 EST640918 ENSG00000154258 "ATP binding cassette subfamily A member 9" Q8IUA7 17 68974488-69060949 "Predicted membrane proteins, Transporters" Transport Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Fibro-adipogenic progenitors: 1225.7;Fibroblasts: 487.7;Leydig cells: 419.5" "Group enriched" "Detected in all" 8 "fibroblast: 1809.6;pericyte: 471.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Pancreas - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052113, HPA054823" Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 5: Non-specific - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA052113: , HPA054823: " "unprognostic (1.73e-1)" "unprognostic (1.08e-1)" "potential prognostic favorable (5.14e-4)" "unprognostic (2.50e-2)" "unprognostic (6.61e-2)" "unprognostic (1.25e-1)" "unprognostic (2.05e-3)" "unprognostic (2.29e-2)" "unprognostic (2.44e-1)" "validated prognostic favorable (7.26e-4)" "validated prognostic favorable (2.49e-5)" "unprognostic (6.00e-2)" "unprognostic (9.76e-2)" "unprognostic (1.90e-1)" "unprognostic (2.06e-1)" "unprognostic (1.70e-1)" "potential prognostic favorable (5.67e-4)" "unprognostic (9.58e-2)" "unprognostic (2.38e-2)" "potential prognostic unfavorable (2.66e-4)" "unprognostic (3.06e-3)" "unprognostic (1.84e-1)" ABCB1 "ABC20, CD243, CLCS, GP170, MDR1, p-170, P-gp, PGY1" ENSG00000085563 "ATP binding cassette subfamily B member 1" P08183 7 87503017-87713323 "Cancer-related genes, CD markers, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 96.1;intestine: 66.6" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 747.9;Colonocytes: 256.0;Enterocytes: 630.7;Hematopoietic stem cells: 640.0;Innate lymphoid cells: 147.7;NK-cells: 216.6;Thymocytes: 162.6;Vascular endothelial cells: 507.4" "Cell type enriched" "Detected in many" 23 "endothelial cell: 4738.8" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 35.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 27.2;NK-cell: 17.9" "Group enriched" "Detected in many" 9 "NK-cells: 17.9;T-cells: 27.2" "Cancer enhanced" "Detected in many" "colorectal cancer: 26.0;liver cancer: 17.4" "Adrenal gland - Adrenal cortex cells, Prostate - Endothelial cells, Spleen - NK-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001716, HPA002199, HPA074614" Enhanced Supported "Plasma membrane" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 47: Endothelial cells - Vasculature" "Cluster 70: DU4475 - Unknown function" "Cluster 104: Brain endothelial cells - Blood brain barrier" 10 "Plasma membrane" "CAB001716: , HPA002199: , HPA074614: " "unprognostic (5.03e-2)" "unprognostic (1.00e-1)" "unprognostic (8.89e-2)" "unprognostic (7.32e-3)" "unprognostic (8.80e-3)" "unprognostic (1.58e-1)" "potential prognostic favorable (2.30e-8)" "unprognostic (9.76e-3)" "unprognostic (1.75e-1)" "unprognostic (1.06e-2)" "unprognostic (7.36e-2)" "unprognostic (2.74e-2)" "unprognostic (7.12e-2)" "unprognostic (3.61e-3)" "unprognostic (1.10e-1)" "unprognostic (3.54e-1)" "unprognostic (2.71e-2)" "unprognostic (1.33e-2)" "unprognostic (1.21e-1)" "unprognostic (8.59e-2)" "unprognostic (1.90e-1)" ABCB10 "EST20237, M-ABC2, MTABC2" ENSG00000135776 "ATP binding cassette subfamily B member 10" Q9NRK6 1 229516582-229558707 "Plasma proteins, Predicted membrane proteins, Transporters" Transport Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 56.7" "Cell type enriched" "Detected in many" 4 "Erythrocyte progenitors: 338.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB044063, CAB044065, HPA055175" Uncertain NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 15: Bone marrow - Innate immune response" "Cluster 15: Non-specific - Transcription" "Cluster 3: Rhabdoid - Membrane components" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 8 "CAB044063: , CAB044065: , HPA055175: " "unprognostic (3.99e-2)" "unprognostic (6.57e-2)" "unprognostic (2.18e-1)" "unprognostic (6.56e-2)" "unprognostic (2.64e-2)" "unprognostic (1.47e-1)" "unprognostic (1.84e-1)" "unprognostic (9.93e-3)" "unprognostic (5.31e-3)" "unprognostic (4.03e-1)" "potential prognostic favorable (1.75e-6)" "unprognostic (4.62e-2)" "unprognostic (4.03e-2)" "unprognostic (7.38e-2)" "unprognostic (5.83e-2)" "unprognostic (1.87e-2)" "unprognostic (2.28e-2)" "unprognostic (1.80e-1)" "unprognostic (3.25e-1)" "unprognostic (2.83e-2)" "unprognostic (8.10e-2)" "unprognostic (2.76e-1)" "unprognostic (3.04e-1)" "unprognostic (1.56e-1)" "potential prognostic favorable (9.21e-4)" "unprognostic (2.40e-2)" "unprognostic (1.67e-1)" "unprognostic (1.86e-1)" "unprognostic (1.11e-1)" "unprognostic (1.64e-2)" "unprognostic (3.87e-1)" ABCB11 "ABC16, BSEP, PFIC-2, PFIC2, PGY4, SPGP" ENSG00000073734 "ATP binding cassette subfamily B member 11" O95342 2 168915498-169031324 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "liver: 75.3" "Group enriched" "Detected in some" 4 "Hepatocytes: 309.0;Müller glia: 138.6" "Cell type enriched" "Detected in many" 4 "ependymal cell: 74.3" "Cancer enriched" "Detected in single" 112 "Liver Hepatocellular Carcinoma (TCGA): 28.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "liver cancer: 1.8" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA019035 Enhanced Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 46: Brainstem - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 93: Hepatocytes - Bile production & excretion" 1 "Nucleoplasm, Plasma membrane, Cytosol" "HPA019035: " "unprognostic (4.43e-2)" "potential prognostic favorable (3.21e-8)" "unprognostic (5.78e-3)" ABCB4 "GBD1, MDR2, MDR3, PFIC-3, PGY3" ENSG00000005471 "ATP binding cassette subfamily B member 4" P21439 7 87401696-87480435 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "liver: 115.1" "Cell type enriched" "Detected in many" 5 "Hepatocytes: 614.1" "Group enriched" "Detected in many" 4 "central nervous system macrophage: 26.6;endothelial cell: 25.7;lower rhombic lip: 12.0" "Cancer enriched" "Detected in some" 10 "Liver Hepatocellular Carcinoma (TCGA): 36.5" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "memory B-cell: 4.4;naive B-cell: 8.2" "Lineage enriched" "Detected in many" 7 "B-cells: 8.2" "Cancer enhanced" "Detected in some" "skin cancer: 9.0" "Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Minor Salivary Gland - Fibroblasts, Skeletal muscle - Skeletal myocytes, Spleen - B-cells (Spleen), Stomach - Fibroblasts" "Low region specificity" "Detected in many" "HPA049395, HPA053288" Enhanced Approved "Nucleoplasm,Plasma membrane,Focal adhesion sites,Cytosol" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 49: Hindbrain - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 93: Hepatocytes - Bile production & excretion" "Nucleoplasm, Plasma membrane" "Focal adhesion sites, Cytosol" "HPA049395: , HPA053288: " "unprognostic (5.25e-2)" "unprognostic (1.31e-1)" "unprognostic (4.84e-2)" "unprognostic (1.73e-1)" "potential prognostic favorable (2.60e-5)" "unprognostic (1.32e-2)" "unprognostic (9.38e-2)" "unprognostic (2.06e-3)" "potential prognostic favorable (9.66e-7)" "unprognostic (2.49e-1)" "unprognostic (1.67e-3)" "unprognostic (7.84e-3)" "unprognostic (2.42e-1)" "unprognostic (2.60e-1)" ABCB5 "ABCB5alpha, ABCB5beta, EST422562" ENSG00000004846 "ATP binding cassette subfamily B member 5" Q2M3G0 7 20615667-20777038 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "epididymis: 25.7" "Group enriched" "Detected in many" 4 "Epididymal principal cells: 244.0;Innate lymphoid cells: 87.9;Melanocytes: 219.9" "Cell type enriched" "Detected in some" 4 "CGE interneuron: 7.1" "Group enriched" "Detected in some" 13 "Kidney Renal Papillary Cell Carcinoma (TCGA): 9.7;Skin Cutaneous Melanoma (TCGA): 29.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 13 "skin cancer: 39.2" "Adipose visceral - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 48: Non-specific - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" "unprognostic (5.24e-1)" "unprognostic (2.55e-1)" "potential prognostic unfavorable (2.68e-4)" "unprognostic (5.01e-2)" "unprognostic (2.65e-2)" "unprognostic (2.61e-2)" "unprognostic (1.71e-1)" "unprognostic (7.60e-2)" ABCB6 "EST45597, MTABC3, umat" ENSG00000115657 "ATP binding cassette subfamily B member 6 (Langereis blood group)" Q9NP58 2 219209772-219218994 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport Translocase "Disease variant, Dyskeratosis congenita, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 7 "Astrocytes: 16.8;Bergmann glia: 11.0;Brain excitatory neurons: 15.5;Brain inhibitory neurons: 18.9;Choroid plexus epithelial cells: 9.2;Ependymal cells: 12.7;Oligodendrocyte progenitor cells: 12.3;Oligodendrocytes: 8.7;Other brain neurons: 21.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046723, HPA058011" Approved Supported "Nucleoplasm,Golgi apparatus,Plasma membrane,Mitochondria,Cytosol,Mid piece,Principal piece" "Intracellular and membrane" Transport NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 35: Neurons - Synaptic function & neurogenesis" "Golgi apparatus" "Nucleoplasm, Plasma membrane, Mitochondria, Cytosol, Mid piece, Principal piece" "HPA046723: , HPA058011: " "unprognostic (4.36e-2)" "unprognostic (8.72e-3)" "unprognostic (1.88e-1)" "unprognostic (3.59e-2)" "unprognostic (4.22e-1)" "unprognostic (5.58e-3)" "unprognostic (5.85e-2)" "potential prognostic favorable (8.68e-4)" "unprognostic (2.17e-1)" "unprognostic (6.76e-2)" "potential prognostic favorable (1.37e-7)" "unprognostic (3.26e-2)" "potential prognostic unfavorable (5.98e-4)" "unprognostic (4.80e-2)" "potential prognostic unfavorable (1.89e-4)" "unprognostic (1.65e-3)" "unprognostic (7.42e-2)" "unprognostic (2.09e-1)" "unprognostic (1.93e-2)" "unprognostic (3.19e-1)" "unprognostic (2.12e-2)" "unprognostic (6.36e-3)" "unprognostic (1.75e-1)" "unprognostic (1.25e-1)" "unprognostic (1.16e-1)" "unprognostic (7.91e-2)" "unprognostic (4.57e-1)" "unprognostic (9.85e-2)" "unprognostic (2.88e-1)" "unprognostic (9.88e-3)" "unprognostic (5.17e-2)" ABCB7 "ABC7, ASAT, Atm1p, EST140535" ENSG00000131269 "ATP binding cassette subfamily B member 7" O75027 X 75051048-75156732 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034982 Approved Approved Mitochondria NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cellular respiration" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 36: Non-specific - mRNA processing" "Cluster 7: Non-specific - Transcription" 8 Mitochondria "HPA034982: " "unprognostic (7.80e-2)" "unprognostic (3.80e-2)" "unprognostic (6.10e-2)" "unprognostic (8.43e-2)" "unprognostic (4.67e-2)" "unprognostic (3.17e-3)" "unprognostic (6.79e-2)" "unprognostic (2.41e-1)" "unprognostic (4.10e-2)" "unprognostic (1.39e-1)" "potential prognostic favorable (6.70e-8)" "unprognostic (2.90e-3)" "unprognostic (1.54e-1)" "unprognostic (8.89e-2)" "unprognostic (1.47e-2)" "unprognostic (2.80e-1)" "unprognostic (9.63e-3)" "unprognostic (4.40e-2)" "unprognostic (1.84e-1)" "unprognostic (7.73e-2)" "unprognostic (1.69e-1)" "unprognostic (5.35e-2)" "unprognostic (1.01e-1)" "unprognostic (6.77e-2)" "unprognostic (7.73e-2)" "unprognostic (1.40e-2)" "unprognostic (2.20e-1)" "unprognostic (5.34e-2)" "unprognostic (1.27e-1)" "unprognostic (3.14e-1)" "unprognostic (3.72e-2)" ABCB8 "EST328128, M-ABC1, MABC1, MITOSUR" ENSG00000197150 "ATP binding cassette subfamily B member 8" Q9NUT2 7 151028422-151047782 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Retinal ganglion cells: 77.3;Syncytiotrophoblasts: 113.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045187 Approved Supported Nucleoplasm,Nucleoli,Mitochondria NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 70: Non-specific - Protein processing" "Cluster 6: Non-specific - Immune response" "Cluster 39: Non-specific - Transcription" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 1 Mitochondria "Nucleoplasm, Nucleoli" "HPA045187: " "unprognostic (6.34e-2)" "unprognostic (7.25e-3)" "unprognostic (3.23e-1)" "unprognostic (3.14e-1)" "unprognostic (1.99e-1)" "unprognostic (4.29e-2)" "unprognostic (3.14e-3)" "unprognostic (1.46e-1)" "unprognostic (5.33e-3)" "unprognostic (2.68e-2)" "unprognostic (3.71e-3)" "unprognostic (1.49e-2)" "unprognostic (5.13e-2)" "unprognostic (2.85e-3)" "unprognostic (6.77e-2)" "unprognostic (5.66e-2)" "unprognostic (3.14e-2)" "unprognostic (1.75e-1)" "unprognostic (2.20e-1)" "unprognostic (5.95e-2)" "unprognostic (3.66e-1)" "unprognostic (1.01e-2)" "unprognostic (1.77e-1)" "unprognostic (1.15e-1)" "unprognostic (1.34e-1)" "unprognostic (1.93e-1)" "unprognostic (1.22e-1)" "unprognostic (8.14e-2)" "unprognostic (2.62e-1)" "potential prognostic unfavorable (2.65e-4)" "unprognostic (1.38e-1)" ABCB9 EST122234 ENSG00000150967 "ATP binding cassette subfamily B member 9" Q9NP78 12 122920951-122981649 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Peptide transport, Protein transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 19.5;testis: 17.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 274.3;Epicardial cells: 72.8;Plasma cells: 134.7;Retinal ganglion cells: 100.4;Tuft cells: 103.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Kidney - Fibroblasts, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Corticotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033052, HPA035113, HPA035114" Approved Supported Vesicles NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 27: Cerebellum - Synaptic function" "Cluster 37: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 44: Plasma cells - Antibody production & secretion" Vesicles "CAB033052: , HPA035113: , HPA035114: " "unprognostic (1.30e-1)" "unprognostic (3.96e-3)" "unprognostic (7.78e-2)" "unprognostic (4.06e-2)" "unprognostic (8.85e-2)" "unprognostic (4.77e-2)" "unprognostic (3.18e-2)" "unprognostic (2.47e-1)" "unprognostic (2.88e-1)" "unprognostic (1.03e-3)" "validated prognostic unfavorable (6.10e-7)" "validated prognostic unfavorable (2.04e-4)" "unprognostic (2.51e-1)" "unprognostic (1.11e-2)" "unprognostic (1.05e-2)" "unprognostic (2.99e-1)" "unprognostic (1.17e-2)" "unprognostic (2.12e-1)" "unprognostic (3.03e-2)" "unprognostic (2.82e-1)" "unprognostic (2.38e-1)" "unprognostic (7.22e-2)" "unprognostic (1.35e-2)" "unprognostic (2.73e-1)" "unprognostic (3.68e-1)" "unprognostic (1.96e-3)" "unprognostic (6.51e-3)" "unprognostic (2.62e-2)" "unprognostic (3.10e-1)" "unprognostic (7.42e-3)" "unprognostic (1.96e-1)" ABCC1 "GS-X, MRP, MRP1" ENSG00000103222 "ATP binding cassette subfamily C member 1" P33527 16 15949138-16143257 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Hydrolase, Translocase" "Cancer-related genes, Deafness, FDA approved drug targets, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 183.8;Papillary tip epithelial cells: 73.9;Podocytes: 98.6;Renal collecting duct intercalated cells: 104.3;Renal collecting duct principal cells: 72.1;Renal connecting tubule cells: 67.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002380, HPA076011" Uncertain Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 21: Non-specific - Metabolism" "Cluster 7: Liver cancer - Metabolism" "Cluster 102: Non-specific - Mixed function" 13 "Plasma membrane" "Cell Junctions" "HPA002380: , HPA076011: " "unprognostic (9.49e-2)" "unprognostic (3.68e-1)" "unprognostic (1.30e-1)" "unprognostic (9.60e-2)" "unprognostic (6.27e-2)" "unprognostic (7.13e-2)" "unprognostic (1.71e-1)" "unprognostic (1.96e-1)" "unprognostic (2.04e-1)" "potential prognostic favorable (1.30e-5)" "unprognostic (3.17e-1)" "unprognostic (1.47e-1)" "unprognostic (1.12e-1)" "unprognostic (9.51e-2)" "unprognostic (1.13e-1)" "unprognostic (1.36e-1)" "unprognostic (2.77e-2)" "unprognostic (4.25e-2)" "unprognostic (3.61e-2)" "unprognostic (9.51e-3)" "unprognostic (1.99e-1)" "unprognostic (1.63e-1)" "unprognostic (5.58e-3)" "unprognostic (4.55e-2)" "unprognostic (2.40e-1)" "unprognostic (3.35e-1)" "unprognostic (7.70e-2)" "unprognostic (2.49e-2)" "unprognostic (3.06e-1)" ABCC10 "EST182763, MRP7, SIMRP7" ENSG00000124574 "ATP binding cassette subfamily C member 10" Q5T3U5 6 43427366-43450427 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA041607, HPA045464" Approved NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 64: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" "HPA041607: , HPA045464: " "unprognostic (1.97e-1)" "unprognostic (3.75e-1)" "unprognostic (2.40e-2)" "unprognostic (1.58e-1)" "unprognostic (1.46e-1)" "unprognostic (3.05e-1)" "unprognostic (2.36e-2)" "unprognostic (4.35e-3)" "unprognostic (3.94e-2)" "potential prognostic favorable (4.58e-4)" "validated prognostic unfavorable (1.27e-7)" "validated prognostic unfavorable (7.48e-4)" "unprognostic (1.59e-3)" "potential prognostic unfavorable (3.87e-4)" "unprognostic (6.33e-2)" "unprognostic (4.56e-2)" "unprognostic (2.09e-2)" "unprognostic (2.91e-2)" "unprognostic (1.54e-2)" "unprognostic (1.22e-1)" "unprognostic (3.01e-1)" "unprognostic (2.03e-1)" "unprognostic (6.76e-2)" "unprognostic (3.20e-2)" "unprognostic (1.19e-1)" "unprognostic (3.96e-1)" "unprognostic (1.33e-2)" "unprognostic (1.88e-1)" "unprognostic (1.13e-1)" "unprognostic (1.00e-1)" "unprognostic (4.97e-2)" ABCC11 MRP8 ENSG00000121270 "ATP binding cassette subfamily C member 11" Q96J66 16 48165773-48247568 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "breast: 43.7" "Cell type enhanced" "Detected in many" "Adipocytes: 103.5;Cardiomyocytes: 554.5;Epicardial cells: 218.3;Epididymal efferent duct absorptive cells: 34.3;Melanocytes: 49.9" "Cell type enhanced" "Detected in many" "Bergmann glia: 9.2" "Cancer enriched" "Detected in some" 5 "Breast Invasive Carcinoma (TCGA): 17.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "breast cancer: 11.0;prostate cancer: 4.7" "Adipose visceral - Adipocytes (Visceral), Pituitary gland - Undifferentiated cells (Pituitary gland), Prostate - Prostate glandular cells, Skin - Sebaceous gland cells, Testis - Early spermatids" "Not detected" "Not detected" NA NA "Cluster 55: Breast - Lactation" "Cluster 6: Non-specific - Immune response" "Cluster 27: Breast cancer - Unknown function" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 1 "unprognostic (6.13e-2)" "unprognostic (1.96e-1)" "unprognostic (8.28e-2)" "unprognostic (5.15e-2)" "unprognostic (6.30e-2)" "unprognostic (9.46e-3)" ABCC12 MRP9 ENSG00000140798 "ATP binding cassette subfamily C member 12" 16 48080882-48156018 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 4 "skeletal muscle: 1.3;testis: 2.2" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 3.6;Breast hormone-responsive cells: 2.0;Differentiating spermatogonia: 2.1;Early primary spermatocytes: 2.3;Early spermatids: 9.5;Hepatic stellate cells: 6.5;Late primary spermatocytes: 15.3;Late spermatids: 6.2;Parietal cells: 1.8;Pituicytes/FSCs: 1.9;Undifferentiated spermatogonia: 2.7" "Cell type enhanced" "Detected in some" "deep-layer intratelencephalic: 7.9;hippocampal CA1-3: 13.9" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Skin - Outer root sheath cells, Testis - Early spermatids" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA043100 Uncertain NA NA "Cluster 61: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" 1 "HPA043100: " "unprognostic (1.44e-1)" ABCC2 "CMOAT, cMRP, DJS, MRP2" ENSG00000023839 "ATP binding cassette subfamily C member 2" Q92887 10 99782640-99852594 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 37.9;liver: 113.8" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 583.5" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 29.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 63.3;Rhabdoid: 79.2" "Kidney - Proximal tubular cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA071145 Enhanced NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 6: Non-specific - Immune response" "Cluster 7: Liver cancer - Metabolism" "Cluster 93: Hepatocytes - Bile production & excretion" 15 "HPA071145: " "unprognostic (6.73e-3)" "unprognostic (2.25e-1)" "unprognostic (3.38e-1)" "unprognostic (8.66e-2)" "unprognostic (3.75e-3)" "unprognostic (6.93e-3)" "unprognostic (1.93e-2)" "potential prognostic unfavorable (5.54e-5)" "unprognostic (2.14e-1)" "unprognostic (6.60e-2)" "potential prognostic unfavorable (5.77e-7)" "unprognostic (3.62e-1)" "unprognostic (2.36e-1)" "unprognostic (6.11e-3)" "unprognostic (1.92e-2)" "unprognostic (1.93e-1)" "unprognostic (1.43e-3)" "unprognostic (1.02e-2)" "unprognostic (1.42e-1)" "unprognostic (1.71e-1)" ABCC3 "cMOAT2, EST90757, MLP2, MOAT-D, MRP3" ENSG00000108846 "ATP binding cassette subfamily C member 3" O15438 17 50634777-50692253 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 58.1;liver: 49.3" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 816.2;Cholangiocytes: 415.9;Colonocytes: 358.2;Epididymal basal cells: 280.8;Foveolar cells: 490.2;Hepatocytes: 419.5;Pancreatic duct cells: 319.1;Papillary tip epithelial cells: 262.4;Platelets: 720.9" "Group enriched" "Detected in many" 4 "astrocyte: 7.7;central nervous system macrophage: 15.2;deep-layer intratelencephalic: 12.3;ependymal cell: 11.5;leukocyte: 17.0;midbrain-derived inhibitory: 5.1;thalamic excitatory: 16.8;upper-layer intratelencephalic: 4.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 5.1;non-classical monocyte: 6.4" "Lineage enriched" "Detected in many" 5 "monocytes: 6.4" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate basal glandular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB037136, HPA048483" Enhanced Supported "Plasma membrane,Basal body" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 28: Liver & Adrenal gland - Secretion" "Cluster 39: Astrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 18: Adrenal cortex cells - Steroidogensis" "Plasma membrane" "Basal body" "CAB037136: , HPA048483: " "unprognostic (1.23e-2)" "unprognostic (3.14e-3)" "unprognostic (1.03e-1)" "unprognostic (8.03e-2)" "unprognostic (5.45e-2)" "unprognostic (8.98e-2)" "unprognostic (5.60e-3)" "unprognostic (1.16e-2)" "unprognostic (1.86e-3)" "potential prognostic favorable (6.36e-4)" "unprognostic (5.22e-2)" "unprognostic (1.38e-1)" "potential prognostic unfavorable (2.43e-4)" "unprognostic (1.75e-1)" "unprognostic (1.20e-1)" "unprognostic (1.33e-1)" "unprognostic (1.48e-2)" "unprognostic (1.69e-1)" "unprognostic (8.19e-3)" "unprognostic (2.14e-1)" "unprognostic (1.05e-3)" "unprognostic (3.53e-1)" "unprognostic (3.24e-1)" "unprognostic (1.78e-1)" "unprognostic (2.13e-1)" "unprognostic (1.89e-2)" "unprognostic (1.37e-1)" "unprognostic (2.42e-1)" "unprognostic (6.76e-2)" ABCC4 "EST170205, MOAT-B, MOATB, MRP4" ENSG00000125257 "ATP binding cassette subfamily C member 4" O15439 13 95019835-95301475 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 38.7" "Cell type enhanced" "Detected in many" "Hematopoietic stem cells: 355.2;Mast cells: 410.3;Megakaryocyte progenitors: 381.3;Megakaryocyte-Erythroid progenitors: 529.2;Microglia: 943.8;Platelets: 443.6;Proximal tubule cells: 323.3;Renal collecting duct intercalated cells: 1141.0" "Cell type enriched" "Detected in all" 7 "central nervous system macrophage: 1176.0" "Cancer enriched" "Detected in all" 6 "Prostate Adenocarcinoma (TCGA): 167.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "prostate cancer: 68.3" "Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002476 Enhanced Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 49: HMC-1 - Innate immune response" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 7 "Plasma membrane" "Golgi apparatus, Vesicles" "HPA002476: " "unprognostic (4.59e-3)" "unprognostic (2.05e-1)" "unprognostic (7.27e-2)" "unprognostic (2.72e-2)" "unprognostic (1.30e-1)" "unprognostic (7.23e-2)" "unprognostic (9.68e-2)" "unprognostic (1.39e-2)" "unprognostic (1.69e-1)" "unprognostic (2.89e-1)" "potential prognostic favorable (4.22e-13)" "unprognostic (5.65e-2)" "unprognostic (3.11e-2)" "unprognostic (6.52e-3)" "unprognostic (6.35e-3)" "unprognostic (1.31e-1)" "unprognostic (3.11e-1)" "unprognostic (1.90e-1)" "unprognostic (1.62e-2)" "unprognostic (1.40e-1)" "unprognostic (1.24e-1)" "unprognostic (7.59e-2)" "unprognostic (1.08e-2)" "unprognostic (3.36e-2)" "unprognostic (1.16e-1)" "unprognostic (1.33e-3)" "unprognostic (7.63e-2)" "unprognostic (3.24e-3)" "unprognostic (1.75e-1)" "unprognostic (7.13e-2)" "unprognostic (5.03e-2)" ABCC5 "EST277145, MOAT-C, MRP5, SMRP" ENSG00000114770 "ATP binding cassette subfamily C member 5" O15440 3 183919934-184017939 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Translocase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 515.5;Foveolar cells: 420.9;Myonuclei: 606.2;Retinal pigment epithelial cells: 822.8;Rod photoreceptor cells: 403.4;Thymic myoid cells: 511.2;Urothelial cells: 547.9" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Lung Squamous Cell Carcinoma (TCGA): 108.5" "Region enriched" "Detected in all" 4 "choroid plexus: 323.0" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044067, HPA052295" Uncertain Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 69: Urothelial cells - Basic cellular functions" 5 "Plasma membrane, Cell Junctions" Nucleoplasm "HPA044067: , HPA052295: " "unprognostic (1.25e-1)" "unprognostic (2.28e-2)" "unprognostic (4.27e-1)" "unprognostic (1.20e-1)" "unprognostic (1.94e-2)" "unprognostic (3.41e-2)" "unprognostic (7.04e-2)" "unprognostic (1.75e-2)" "unprognostic (6.06e-2)" "unprognostic (1.09e-1)" "unprognostic (2.12e-2)" "unprognostic (1.36e-1)" "unprognostic (1.19e-1)" "potential prognostic unfavorable (1.11e-6)" "unprognostic (2.25e-1)" "unprognostic (7.96e-2)" "unprognostic (3.76e-1)" "unprognostic (4.44e-3)" "potential prognostic favorable (9.91e-4)" "unprognostic (8.55e-3)" "unprognostic (2.25e-1)" "unprognostic (5.10e-2)" "unprognostic (1.15e-1)" "potential prognostic unfavorable (5.57e-4)" "unprognostic (6.72e-2)" "unprognostic (2.51e-2)" "unprognostic (3.06e-3)" "unprognostic (8.21e-2)" "unprognostic (3.88e-1)" "unprognostic (2.93e-2)" "unprognostic (9.32e-2)" ABCC6 "ARA, EST349056, MLP1, MRP6, PXE, URG7" ENSG00000091262 "ATP binding cassette subfamily C member 6" O95255 16 16149565-16223522 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Sensory transduction, Transport, Vision" Translocase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 21.7;liver: 82.0" "Cell type enriched" "Detected in some" 7 "Proximal tubule cells: 143.0" "Cell type enhanced" "Detected in many" "endothelial cell: 19.5;ependymal cell: 11.0" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 49.1" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "classical monocyte: 3.9" "Lineage enriched" "Detected in single" 5 "monocytes: 3.9" "Cancer enhanced" "Detected in many" "liver cancer: 9.2" "Adipose visceral - Adipocytes (Visceral), Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Alveolar cells type 2" "Not detected" "Not detected" "Not detected" "Not detected" HPA038105 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 3: Choroid plexus - Cilium" "Cluster 18: Liver cancer - Metabolism" "Cluster 88: Proximal tubular cells - Transmembrane transport" 1 "Plasma membrane" Nucleoplasm "HPA038105: " "unprognostic (8.02e-2)" "unprognostic (3.70e-2)" "unprognostic (3.81e-2)" "unprognostic (1.42e-2)" "unprognostic (9.04e-3)" "potential prognostic favorable (2.34e-4)" "unprognostic (3.38e-2)" "unprognostic (8.57e-3)" "unprognostic (3.39e-3)" "unprognostic (4.75e-3)" "unprognostic (1.89e-3)" "unprognostic (7.25e-2)" "unprognostic (7.14e-2)" "unprognostic (4.12e-1)" "unprognostic (1.54e-2)" "unprognostic (1.76e-1)" "unprognostic (2.86e-1)" "unprognostic (3.99e-2)" "unprognostic (5.07e-2)" "unprognostic (7.73e-2)" "unprognostic (9.51e-3)" "unprognostic (2.08e-1)" "unprognostic (2.47e-1)" "unprognostic (1.06e-1)" "potential prognostic unfavorable (2.79e-5)" ABCC8 "ABC36, HHF1, HI, HRINS, MRP8, PHHI, SUR, SUR1, TNDM2" ENSG00000006071 "ATP binding cassette subfamily C member 8" Q09428 11 17392498-17476894 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" Transport Receptor "Diabetes mellitus, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 22.2;pancreas: 13.3;pituitary gland: 23.3" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 191.5;Astrocytes: 40.8;Brain excitatory neurons: 60.7;Brain inhibitory neurons: 36.6;Corticotrophs: 66.2;Endometrial stromal cells: 50.7;Gonadotrophs: 89.8;Neuroendocrine cells: 61.5;Oligodendrocyte progenitor cells: 65.8;Pancreatic islet cells: 264.2;Retinal bipolar cells: 75.3;Somatotrophs: 70.1" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in some" 7 "Pancreatic Adenocarcinoma (TCGA): 23.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 9 "thyroid cancer: 3.4" "Adrenal gland - Adrenal medulla cells, Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Pancreas - Alpha cells, Pancreas - Beta cells, Pituitary gland - Corticotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011451, HPA042318" Approved Approved "Nucleoli,Golgi apparatus,Cytosol,Principal piece" No NA "Cluster 70: Non-specific - Protein processing" "Cluster 24: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" "Nucleoli, Golgi apparatus" "Cytosol, Principal piece" "CAB011451: , HPA042318: " "unprognostic (2.97e-1)" "unprognostic (2.51e-2)" "unprognostic (3.41e-2)" "unprognostic (1.26e-2)" "unprognostic (1.79e-2)" "unprognostic (1.41e-2)" "unprognostic (1.62e-2)" "unprognostic (4.12e-2)" ABCC9 "CMD1O, SUR2" ENSG00000069431 "ATP binding cassette subfamily C member 9" O60706 12 21797389-21942543 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" Transport Receptor "Atrial fibrillation, Cardiomyopathy, Disease variant, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 84.4;Cardiomyocytes: 233.0;Ependymal cells: 168.6;Fibroblasts: 84.3;Hepatocytes: 216.5;Myonuclei: 482.0;Pericytes: 414.1;Smooth muscle cells: 144.3" "Cell type enhanced" "Detected in many" "ependymal cell: 194.8;pericyte: 470.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Pituitary gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007279 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 76: Non-specific - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 110: Mural cells - ECM organization" "Nucleoplasm, Plasma membrane" "HPA007279: " "unprognostic (1.79e-1)" "potential prognostic unfavorable (9.88e-4)" "unprognostic (1.25e-1)" "unprognostic (4.91e-2)" "potential prognostic unfavorable (7.23e-4)" "unprognostic (2.47e-1)" "unprognostic (3.10e-1)" "unprognostic (1.09e-1)" "unprognostic (7.90e-2)" "unprognostic (1.32e-2)" "unprognostic (1.62e-1)" "potential prognostic favorable (1.68e-4)" "unprognostic (5.46e-3)" "unprognostic (1.39e-1)" "unprognostic (8.16e-3)" "unprognostic (2.68e-1)" "unprognostic (1.10e-1)" "unprognostic (2.55e-1)" "unprognostic (5.70e-2)" "unprognostic (8.19e-2)" "unprognostic (9.97e-2)" "unprognostic (1.17e-2)" "unprognostic (1.74e-2)" "unprognostic (2.56e-1)" "unprognostic (7.50e-3)" "unprognostic (7.75e-3)" "unprognostic (9.45e-3)" "unprognostic (1.92e-3)" "unprognostic (1.34e-1)" "unprognostic (3.72e-3)" "unprognostic (1.75e-2)" ABCD1 "adrenoleukodystrophy, ALD, ALDP, AMN" ENSG00000101986 "ATP binding cassette subfamily D member 1" P33897 X 153724856-153744755 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Hydrolase, Translocase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Enterocytes: 52.1;Extravillous trophoblasts: 28.5;Syncytiotrophoblasts: 37.5;Thymic myoid cells: 42.1" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 73.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Prostate - Smooth muscle cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035214 Approved NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 24: Non-specific - Transcription" "Cluster 18: Non-specific - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 1: Enterocytes - Absorption and Digestion" 9 "HPA035214: " "unprognostic (2.98e-1)" "unprognostic (2.14e-2)" "unprognostic (2.49e-3)" "unprognostic (6.51e-2)" "unprognostic (9.29e-2)" "unprognostic (1.79e-2)" "unprognostic (5.80e-2)" "unprognostic (3.79e-1)" "unprognostic (1.47e-1)" "unprognostic (4.73e-2)" "unprognostic (3.92e-3)" "unprognostic (4.43e-3)" "unprognostic (2.58e-1)" "unprognostic (1.45e-3)" "unprognostic (1.76e-1)" "unprognostic (2.34e-2)" "unprognostic (1.00e-1)" "unprognostic (1.58e-1)" "unprognostic (1.35e-2)" "unprognostic (1.68e-1)" "unprognostic (3.52e-2)" "unprognostic (2.45e-1)" "unprognostic (2.51e-1)" "unprognostic (1.60e-1)" "unprognostic (1.68e-1)" "unprognostic (5.43e-2)" "unprognostic (3.49e-2)" "unprognostic (3.10e-2)" "unprognostic (1.21e-1)" "unprognostic (3.07e-2)" "unprognostic (4.81e-3)" ABCD2 "ALDL1, ALDR, ALDRP" ENSG00000173208 "ATP binding cassette subfamily D member 2" Q9UBJ2 12 39550033-39619803 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Hydrolase, Translocase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 14.8" "Cell type enhanced" "Detected in many" "Adipocytes: 376.3;Astrocytes: 115.3;Bergmann glia: 81.0;Brain excitatory neurons: 55.2;Cardiomyocytes: 50.3;Retinal bipolar cells: 215.2;Retinal ganglion cells: 88.8" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in single" 6 "Glioblastoma Multiforme (TCGA): 2.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Lineage enriched" "Detected in single" 4 "T-cells: 4.2" "Group enriched" "Detected in some" 8 "lymphoma: 2.2;Myeloma: 8.2;Neuroblastoma: 3.5" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Skin - Adipocytes (Skin)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 2: Neurons - Nucleosome" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 1 "unprognostic (1.12e-1)" "unprognostic (2.35e-1)" "unprognostic (5.11e-3)" ABCD3 "PMP70, PXMP1, ZWS2" ENSG00000117528 "ATP binding cassette subfamily D member 3" P28288 1 94418389-94518666 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Hydrolase, Translocase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 118.4" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032026, HPA032027, CAB032516, CAB075749" Enhanced Enhanced Peroxisomes NA NA 12000 "Cluster 33: Non-specific - ATP binding" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 55: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 36 Peroxisomes "CAB032516: , CAB075749: , HPA032026: , HPA032027: " "unprognostic (4.91e-3)" "unprognostic (6.45e-2)" "unprognostic (9.71e-2)" "unprognostic (2.35e-1)" "potential prognostic favorable (9.32e-9)" "unprognostic (3.62e-2)" "unprognostic (6.78e-2)" "unprognostic (5.27e-2)" "unprognostic (2.24e-1)" "unprognostic (1.62e-2)" "potential prognostic favorable (8.42e-8)" "unprognostic (1.97e-2)" "unprognostic (5.59e-2)" "unprognostic (8.96e-3)" "unprognostic (4.54e-2)" "unprognostic (1.04e-1)" "unprognostic (1.15e-1)" "unprognostic (3.23e-1)" "unprognostic (2.10e-2)" "unprognostic (1.53e-1)" "unprognostic (2.89e-1)" "unprognostic (9.61e-2)" "unprognostic (6.76e-2)" "unprognostic (2.60e-1)" "unprognostic (1.16e-2)" "unprognostic (4.68e-2)" "unprognostic (1.15e-1)" "unprognostic (1.48e-1)" "unprognostic (2.41e-1)" "unprognostic (1.11e-1)" "unprognostic (1.96e-3)" ABCD4 "EST352188, P70R, PMP69, PXMP1L" ENSG00000119688 "ATP binding cassette subfamily D member 4" O14678 14 74285269-74303055 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Translocase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 112.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003396 Approved NA NA "Cluster 32: Basophils - Transcription" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 25: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 3 "HPA003396: " "unprognostic (5.69e-2)" "unprognostic (2.58e-1)" "unprognostic (1.39e-1)" "potential prognostic unfavorable (1.78e-4)" "unprognostic (2.24e-1)" "unprognostic (1.72e-1)" "unprognostic (2.80e-1)" "unprognostic (7.07e-2)" "unprognostic (3.96e-2)" "unprognostic (3.06e-1)" "potential prognostic favorable (7.45e-5)" "unprognostic (8.35e-3)" "unprognostic (9.72e-2)" "unprognostic (5.38e-3)" "unprognostic (4.04e-2)" "unprognostic (1.61e-1)" "unprognostic (3.54e-1)" "unprognostic (4.61e-2)" "unprognostic (2.09e-1)" "unprognostic (2.73e-2)" "unprognostic (3.15e-1)" "unprognostic (2.34e-2)" "unprognostic (5.78e-2)" "unprognostic (5.85e-2)" "unprognostic (1.54e-1)" "potential prognostic unfavorable (1.70e-5)" "unprognostic (2.69e-3)" "unprognostic (1.03e-1)" "unprognostic (6.17e-2)" "unprognostic (1.04e-1)" "unprognostic (3.62e-3)" ABCE1 "OABP, RLI, RLI1, RNASEL1, RNASELI, RNS4I" ENSG00000164163 "ATP binding cassette subfamily E member 1" P61221 4 145098288-145129524 "Essential proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, Translation regulation" "Chaperone, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012476, HPA036846" Approved Enhanced Cytosol No No 140000 "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 17: Non-specific - RNA processing" 75 Cytosol "CAB012476: , HPA036846: " "unprognostic (2.48e-1)" "unprognostic (2.26e-2)" "unprognostic (1.67e-1)" "unprognostic (2.69e-2)" "unprognostic (7.75e-3)" "unprognostic (7.16e-2)" "unprognostic (1.29e-1)" "unprognostic (7.70e-2)" "unprognostic (1.37e-2)" "unprognostic (1.27e-2)" "potential prognostic favorable (2.93e-5)" "unprognostic (7.08e-2)" "unprognostic (1.67e-1)" "potential prognostic unfavorable (5.27e-4)" "unprognostic (3.74e-2)" "unprognostic (1.17e-3)" "potential prognostic unfavorable (2.59e-4)" "unprognostic (3.25e-1)" "unprognostic (1.33e-1)" "unprognostic (2.78e-2)" "unprognostic (4.44e-2)" "unprognostic (1.08e-3)" "unprognostic (1.89e-2)" "unprognostic (1.43e-2)" "unprognostic (3.17e-3)" "unprognostic (5.55e-2)" "unprognostic (9.38e-2)" "unprognostic (2.04e-1)" "unprognostic (3.84e-1)" "potential prognostic unfavorable (6.34e-4)" "unprognostic (1.19e-1)" ABCF1 "ABC50, EST123147" ENSG00000204574 "ATP binding cassette subfamily F member 1" Q8NE71 6 30571393-30597179 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Transporters" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 141.6;Late spermatids: 151.9;Syncytiotrophoblasts: 126.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017578 Approved Enhanced Cytosol NA NA 210000 "Cluster 33: Non-specific - ATP binding" "Cluster 24: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 13 Cytosol "HPA017578: " "unprognostic (2.42e-2)" "unprognostic (3.84e-2)" "unprognostic (7.00e-3)" "unprognostic (1.15e-1)" "potential prognostic favorable (7.20e-5)" "unprognostic (3.97e-1)" "unprognostic (3.67e-2)" "unprognostic (1.17e-1)" "unprognostic (4.07e-1)" "unprognostic (2.97e-1)" "unprognostic (4.54e-2)" "unprognostic (1.83e-1)" "unprognostic (8.10e-3)" "unprognostic (1.95e-1)" "unprognostic (7.40e-3)" "unprognostic (1.97e-1)" "unprognostic (1.60e-1)" "unprognostic (1.28e-1)" "unprognostic (1.97e-1)" "unprognostic (1.69e-1)" "unprognostic (1.80e-1)" "unprognostic (3.77e-1)" "unprognostic (4.15e-3)" "unprognostic (5.09e-2)" "unprognostic (1.61e-1)" "unprognostic (5.59e-2)" "unprognostic (1.50e-1)" "unprognostic (3.12e-2)" "unprognostic (3.89e-2)" "unprognostic (2.17e-2)" "unprognostic (6.36e-2)" ABCF2 "ABC28, EST133090, HUSSY-18, M-ABC1" ENSG00000033050 "ATP binding cassette subfamily F member 2" Q9UG63 7 151211484-151227205 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Astrocytes: 10.2;Bergmann glia: 8.3;Brain excitatory neurons: 15.0;Brain inhibitory neurons: 14.6;Choroid plexus epithelial cells: 8.2;Ependymal cells: 8.9;Microglia: 7.3;Oligodendrocyte progenitor cells: 9.5;Oligodendrocytes: 11.2;Other brain neurons: 15.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020091, CAB020682, HPA021815, HPA030388" Approved Enhanced Cytosol NA NA 3800 "Cluster 13: Non-specific - Mitochondria" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 39: Non-specific - Transcription" "Cluster 98: Neurons - Neurotransmission & signaling" 17 Cytosol "CAB020682: , HPA020091: , HPA021815: , HPA030388: " "unprognostic (1.69e-1)" "unprognostic (2.92e-3)" "unprognostic (8.70e-2)" "unprognostic (1.65e-1)" "unprognostic (1.64e-1)" "unprognostic (7.80e-2)" "unprognostic (5.62e-2)" "unprognostic (1.82e-1)" "unprognostic (7.64e-2)" "potential prognostic unfavorable (4.51e-5)" "unprognostic (2.03e-2)" "unprognostic (3.09e-2)" "unprognostic (3.08e-1)" "potential prognostic unfavorable (1.81e-9)" "unprognostic (9.49e-3)" "unprognostic (7.68e-3)" "unprognostic (2.02e-2)" "unprognostic (4.01e-2)" "unprognostic (8.92e-2)" "unprognostic (3.61e-2)" "unprognostic (6.07e-2)" "unprognostic (2.73e-2)" "unprognostic (9.50e-2)" "unprognostic (8.80e-2)" "unprognostic (3.06e-1)" "unprognostic (1.13e-1)" "unprognostic (3.89e-2)" "unprognostic (1.09e-1)" "unprognostic (4.14e-1)" "unprognostic (5.17e-2)" "unprognostic (1.34e-2)" ABCF2-H2BK1 ABCF2-H2BE1 ENSG00000285292 "ABCF2-H2BK1 readthrough" 7 151207837-151227166 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in some" 4 "Hepatic stellate cells: 6.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA020091, HPA021815, HPA030388" Approved Uncertain Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 39: Non-specific - Transcription" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" Cytosol "HPA020091: , HPA021815: , HPA030388: " "potential prognostic unfavorable (2.91e-4)" "unprognostic (2.69e-1)" "unprognostic (2.38e-1)" "unprognostic (2.77e-1)" "unprognostic (1.15e-1)" "unprognostic (3.33e-1)" "unprognostic (2.11e-2)" "unprognostic (5.79e-3)" "potential prognostic favorable (6.97e-7)" "unprognostic (1.74e-1)" "unprognostic (6.77e-3)" "unprognostic (2.63e-2)" "unprognostic (1.31e-2)" "unprognostic (3.97e-3)" "unprognostic (1.37e-1)" "unprognostic (1.89e-2)" "unprognostic (9.42e-2)" "unprognostic (2.55e-2)" "unprognostic (1.05e-1)" "unprognostic (4.37e-2)" "unprognostic (7.88e-2)" "unprognostic (1.67e-1)" "unprognostic (8.42e-2)" "unprognostic (1.78e-1)" "unprognostic (4.50e-2)" "unprognostic (1.26e-1)" ABCF3 EST201864 ENSG00000161204 "ATP binding cassette subfamily F member 3" Q9NUQ8 3 184186095-184194012 "Predicted intracellular proteins, Transporters" "Antiviral defense" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 53.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Prostate basal glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036332 Approved Approved Nucleoli,Cytosol NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 63: Non-specific - Protein processing" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 4 Cytosol Nucleoli "HPA036332: " "unprognostic (2.97e-2)" "unprognostic (4.37e-2)" "unprognostic (1.64e-1)" "unprognostic (6.08e-2)" "unprognostic (1.07e-1)" "unprognostic (1.52e-1)" "unprognostic (1.74e-1)" "unprognostic (1.19e-3)" "unprognostic (1.93e-1)" "unprognostic (4.50e-2)" "potential prognostic favorable (4.66e-6)" "unprognostic (1.12e-2)" "unprognostic (2.16e-1)" "unprognostic (2.13e-2)" "unprognostic (3.32e-2)" "unprognostic (3.26e-2)" "unprognostic (4.38e-3)" "unprognostic (5.08e-2)" "potential prognostic favorable (2.67e-4)" "unprognostic (1.93e-1)" "unprognostic (1.03e-1)" "unprognostic (1.07e-1)" "unprognostic (8.19e-3)" "unprognostic (2.01e-1)" "unprognostic (1.20e-1)" "unprognostic (2.16e-1)" "unprognostic (3.42e-2)" "unprognostic (1.92e-1)" "unprognostic (3.49e-1)" "unprognostic (1.55e-1)" "unprognostic (2.77e-1)" ABCG1 ABC8 ENSG00000160179 "ATP binding cassette subfamily G member 1" P45844 21 42199689-42297244 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Kupffer cells: 265.5;Neutrophils: 269.4;Rod photoreceptor cells: 223.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "eosinophil: 35.7;neutrophil: 36.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 36.8" "Low cancer specificity" "Detected in many" "Liver - Vascular endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031470, HPA031471" Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 2 "Golgi apparatus, Vesicles" "HPA031470: , HPA031471: " "unprognostic (5.88e-2)" "unprognostic (2.82e-2)" "unprognostic (2.57e-1)" "unprognostic (1.11e-2)" "unprognostic (2.77e-1)" "unprognostic (5.22e-2)" "unprognostic (7.28e-2)" "unprognostic (8.56e-2)" "unprognostic (3.81e-1)" "unprognostic (1.62e-1)" "validated prognostic favorable (8.64e-9)" "validated prognostic favorable (9.01e-7)" "unprognostic (6.39e-3)" "unprognostic (2.75e-2)" "unprognostic (9.36e-2)" "unprognostic (1.28e-1)" "unprognostic (4.21e-2)" "unprognostic (2.08e-1)" "unprognostic (4.41e-2)" "unprognostic (2.27e-3)" "potential prognostic unfavorable (6.54e-4)" "unprognostic (1.93e-3)" "unprognostic (2.99e-1)" "unprognostic (1.01e-2)" "unprognostic (2.76e-1)" "unprognostic (1.17e-1)" "unprognostic (6.32e-2)" "unprognostic (1.08e-2)" "unprognostic (2.41e-2)" "unprognostic (1.08e-1)" "unprognostic (1.31e-2)" ABCG2 "ABCP, BCRP, CD338, EST157481, MXR" ENSG00000118777 "ATP binding cassette subfamily G member 2 (Junior blood group)" Q9UNQ0 4 88090150-88231628 "Cancer-related genes, CD markers, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 83.2" "Group enriched" "Detected in many" 4 "Breast lactating cells: 316.5;Colonocytes: 104.6;Enterocytes: 267.3;Extravillous trophoblasts: 116.4;Hofbauer cells: 298.9;Vascular endothelial cells: 142.0" "Cell type enriched" "Detected in many" 17 "endothelial cell: 1911.5" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 17.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 2.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB037299, HPA054719" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 47: Endothelial cells - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 104: Brain endothelial cells - Blood brain barrier" 6 "Plasma membrane" Nucleoplasm "CAB037299: , HPA054719: " "unprognostic (9.74e-2)" "unprognostic (1.82e-1)" "unprognostic (5.75e-2)" "unprognostic (4.47e-1)" "unprognostic (1.39e-1)" "potential prognostic favorable (2.42e-4)" "unprognostic (1.22e-1)" "unprognostic (1.71e-1)" "unprognostic (5.98e-3)" "validated prognostic favorable (3.55e-15)" "validated prognostic favorable (5.94e-5)" "unprognostic (1.76e-1)" "unprognostic (1.22e-1)" "unprognostic (2.82e-2)" "unprognostic (7.57e-2)" "unprognostic (4.10e-1)" "unprognostic (2.17e-1)" "unprognostic (3.04e-1)" "unprognostic (4.54e-3)" "unprognostic (4.03e-2)" "unprognostic (7.26e-2)" "unprognostic (2.56e-1)" "unprognostic (4.62e-2)" "unprognostic (1.84e-1)" "unprognostic (2.73e-2)" "unprognostic (9.90e-2)" "unprognostic (2.80e-1)" "unprognostic (9.01e-2)" ABCG4 WHITE2 ENSG00000172350 "ATP binding cassette subfamily G member 4" Q9H172 11 119149052-119162653 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 22.2;retina: 48.3" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 7.9;Brain inhibitory neurons: 8.7;Cone photoreceptor cells: 35.2;Epicardial cells: 4.5;Esophageal apical cells: 7.1;Other brain neurons: 8.2;Retinal amacrine cells: 4.8;Retinal bipolar cells: 10.2;Retinal horizontal cells: 8.0;Rod photoreceptor cells: 41.3" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 27.6" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 1.4" "Colon - Colon enteroendocrine cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057635 Enhanced NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 1: Neuronal - Visual perception" "Cluster 109: Neurons - Neuronal signaling" 5 "HPA057635: " "unprognostic (2.68e-1)" ABCG5 STSL ENSG00000138075 "ATP binding cassette subfamily G member 5" Q9H222 2 43812472-43838865 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 69 "intestine: 45.0;liver: 59.6" "Group enriched" "Detected in some" 9 "Enterocytes: 47.6;Hepatocytes: 106.6" "Cell type enhanced" "Detected in many" "midbrain-derived inhibitory: 17.0" "Cancer enriched" "Detected in single" 25 "Liver Hepatocellular Carcinoma (TCGA): 13.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" NA NA "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 18: Liver cancer - Metabolism" "Cluster 93: Hepatocytes - Bile production & excretion" "potential prognostic favorable (4.17e-4)" "unprognostic (1.45e-1)" ABCG8 GBD4 ENSG00000143921 "ATP binding cassette subfamily G member 8" Q9H221 2 43831942-43882988 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 44 "intestine: 29.6;liver: 45.8" "Group enriched" "Detected in some" 6 "Enterocytes: 54.4;Hepatocytes: 134.8" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in single" 15 "Liver Hepatocellular Carcinoma (TCGA): 15.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA019556 Uncertain Approved Vesicles NA NA "Cluster 77: Intestine - Digestion" "Cluster 9: Non-specific - Receptor signaling" "Cluster 18: Liver cancer - Metabolism" "Cluster 93: Hepatocytes - Bile production & excretion" 1 Vesicles "HPA019556: " "unprognostic (2.02e-1)" "unprognostic (3.39e-3)" "unprognostic (3.16e-2)" "unprognostic (2.04e-1)" ABHD1 "FLJ36128, LABH1" ENSG00000143994 "Abhydrolase domain containing 1" Q96SE0 2 27123789-27130812 "Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 19.9" "Cell type enriched" "Detected in many" 6 "Late spermatids: 1933.0" "Cell type enhanced" "Detected in many" "astrocyte: 7.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "prostate cancer: 1.0" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044390 Uncertain NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 67: Testis - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 20: Myeloma - Immune response" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 1 "HPA044390: " "unprognostic (2.22e-1)" "unprognostic (4.62e-3)" "unprognostic (3.80e-2)" "unprognostic (2.95e-1)" ABHD10 FLJ11342 ENSG00000144827 "Abhydrolase domain containing 10, depalmitoylase" Q9NUJ1 3 111979010-111993368 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 74.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Prostate - Prostate glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036991, HPA036992, HPA066081" Supported Approved Mitochondria No No 63000 "Cluster 32: Basophils - Transcription" "Cluster 76: Non-specific - Metabolism" "Cluster 31: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 25 Mitochondria "HPA036991: , HPA036992: , HPA066081: " "unprognostic (1.65e-2)" "unprognostic (1.47e-1)" "unprognostic (5.19e-3)" "unprognostic (4.01e-1)" "unprognostic (4.93e-2)" "unprognostic (1.13e-1)" "unprognostic (5.74e-2)" "unprognostic (6.27e-2)" "unprognostic (1.17e-2)" "unprognostic (7.31e-2)" "potential prognostic favorable (1.05e-6)" "unprognostic (2.41e-1)" "unprognostic (1.05e-3)" "unprognostic (2.36e-2)" "unprognostic (1.30e-1)" "unprognostic (3.86e-2)" "unprognostic (1.34e-1)" "unprognostic (7.44e-2)" "unprognostic (1.67e-1)" "unprognostic (3.41e-1)" "unprognostic (3.24e-3)" "unprognostic (3.29e-1)" "unprognostic (7.62e-3)" "unprognostic (1.60e-1)" "unprognostic (1.39e-1)" "unprognostic (3.31e-1)" "unprognostic (1.31e-1)" "unprognostic (2.66e-2)" "unprognostic (3.03e-1)" "unprognostic (8.16e-3)" "unprognostic (2.20e-2)" ABHD11 "PP1226, WBSCR21" ENSG00000106077 "Abhydrolase domain containing 11" Q8NFV4 7 73736094-73738852 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hydrolase "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 133.3;Megakaryocytes: 166.9;Migrating cytotrophoblasts: 162.7;Syncytiotrophoblasts: 149.4;Urothelial cells: 132.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024042, HPA049641" Approved Supported Mitochondria NA NA 7900 "Cluster 40: Monocytes - Innate immune response" "Cluster 70: Non-specific - Protein processing" "Cluster 44: Non-specific - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 51: Secretory epithelial cells - Mixed function" Mitochondria "HPA024042: , HPA049641: " "unprognostic (2.01e-1)" "unprognostic (2.45e-1)" "unprognostic (4.03e-2)" "unprognostic (5.33e-2)" "unprognostic (6.37e-3)" "unprognostic (5.05e-1)" "unprognostic (2.25e-3)" "unprognostic (1.04e-2)" "unprognostic (1.16e-1)" "unprognostic (1.27e-1)" "unprognostic (3.65e-2)" "unprognostic (1.53e-2)" "potential prognostic favorable (8.69e-5)" "unprognostic (1.70e-1)" "unprognostic (1.86e-1)" "unprognostic (1.12e-1)" "unprognostic (1.63e-1)" "unprognostic (5.97e-2)" "unprognostic (5.45e-2)" "unprognostic (3.58e-1)" "unprognostic (1.60e-1)" "unprognostic (5.73e-2)" "unprognostic (1.32e-1)" "unprognostic (7.39e-2)" "unprognostic (8.72e-3)" "unprognostic (3.65e-1)" "unprognostic (2.71e-2)" "unprognostic (9.41e-3)" "unprognostic (4.38e-2)" "unprognostic (2.24e-2)" "unprognostic (6.11e-3)" ABHD12 "ABHD12A, BEM46L2, C20orf22, dJ965G21.2, DKFZP434P106" ENSG00000100997 "Abhydrolase domain containing 12, lysophospholipase" Q8N2K0 20 25294742-25390835 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Cataract, Deafness, Disease variant, Neuropathy, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 325.2;Esophageal apical cells: 496.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Lung - Macrophages, Skin - Keratinocyte (granular), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026866 Uncertain NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." 10 "HPA026866: " "unprognostic (2.27e-1)" "potential prognostic unfavorable (5.88e-4)" "unprognostic (2.13e-2)" "unprognostic (1.20e-1)" "unprognostic (8.86e-2)" "unprognostic (2.70e-1)" "unprognostic (8.21e-2)" "unprognostic (3.34e-1)" "unprognostic (2.25e-2)" "unprognostic (1.44e-1)" "unprognostic (5.32e-3)" "unprognostic (9.87e-2)" "unprognostic (5.02e-2)" "validated prognostic unfavorable (2.40e-4)" "validated prognostic unfavorable (1.20e-4)" "unprognostic (1.72e-1)" "unprognostic (5.72e-3)" "unprognostic (2.12e-3)" "unprognostic (1.04e-1)" "unprognostic (6.10e-2)" "unprognostic (4.92e-2)" "unprognostic (3.29e-1)" "unprognostic (8.13e-2)" "unprognostic (1.23e-1)" "unprognostic (9.53e-2)" "unprognostic (1.20e-2)" "unprognostic (1.22e-1)" "unprognostic (1.93e-1)" "unprognostic (3.24e-1)" "unprognostic (1.88e-1)" "unprognostic (4.07e-2)" ABHD12B "BEM46L3, C14orf29" ENSG00000131969 "Abhydrolase domain containing 12B" Q7Z5M8 14 50872053-50904970 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 6.3;retina: 13.3;skin 1: 9.8" "Cell type enhanced" "Detected in many" "Adipocytes: 63.9;Epicardial cells: 63.7;Müller glia: 233.9;Oocytes: 41.4;Respiratory ciliated cells: 31.3;Retinal ganglion cells: 30.9;Rod photoreceptor cells: 53.1;Thymocytes: 29.6" "Cell type enhanced" "Detected in many" "medium spiny neuron: 29.7;thalamic excitatory: 39.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "eosinophil: 1.0;neutrophil: 2.2" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.2" "Cancer enriched" "Detected in some" 5 "cervical cancer: 5.6" "Adipose visceral - Mesothelial cells, Kidney - Podocytes, Skin - Keratinocyte (granular), Spleen - Neutrophils_2, Testis - Early spermatids" "Region enriched" "Detected in single" 5 "thalamus: 2.1" "Low region specificity" "Detected in many" HPA002873 Uncertain Uncertain Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 11: Muller glia cells - Retinal homeostasis" Nucleoplasm "HPA002873: " "unprognostic (9.85e-2)" "unprognostic (7.12e-2)" "unprognostic (7.46e-2)" "unprognostic (7.74e-2)" "unprognostic (1.50e-2)" "unprognostic (1.40e-2)" "unprognostic (5.11e-2)" ABHD13 "bA153I24.2, BEM46L1, C13orf6, FLJ14906" ENSG00000139826 "Abhydrolase domain containing 13" Q7L211 13 108218392-108234243 "Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 79.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032143, HPA032144" Approved Approved Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 19: Non-specific - Unknown function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" Cytosol "HPA032143: , HPA032144: " "unprognostic (2.65e-1)" "unprognostic (3.99e-1)" "unprognostic (1.74e-1)" "unprognostic (4.48e-2)" "unprognostic (3.10e-1)" "unprognostic (2.08e-3)" "unprognostic (5.99e-2)" "unprognostic (2.69e-1)" "unprognostic (1.84e-2)" "unprognostic (2.20e-1)" "potential prognostic favorable (1.99e-5)" "unprognostic (5.35e-3)" "unprognostic (9.22e-2)" "unprognostic (6.30e-2)" "unprognostic (2.90e-1)" "unprognostic (3.29e-1)" "unprognostic (3.69e-1)" "unprognostic (2.15e-1)" "unprognostic (1.79e-2)" "unprognostic (5.75e-2)" "unprognostic (4.84e-3)" "unprognostic (2.35e-1)" "unprognostic (1.43e-2)" "unprognostic (1.33e-1)" "unprognostic (2.45e-1)" "unprognostic (3.92e-1)" "unprognostic (1.33e-1)" "unprognostic (7.04e-2)" "unprognostic (2.85e-1)" "unprognostic (9.87e-2)" "unprognostic (1.66e-1)" ABHD14A "DKFZP564O243, DORZ1" ENSG00000248487 "Abhydrolase domain containing 14A" Q9BUJ0 3 51971426-51981196 "Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 9 "Cardiomyocytes: 579.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038153, HPA056913" Approved Supported Vesicles NA NA 100000 "Cluster 11: T-cells - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 15 Vesicles "HPA038153: , HPA056913: " "unprognostic (3.13e-3)" "unprognostic (5.39e-3)" "unprognostic (7.94e-3)" "unprognostic (5.99e-2)" "unprognostic (9.14e-2)" "unprognostic (1.37e-1)" "unprognostic (1.08e-1)" "unprognostic (9.65e-2)" "unprognostic (1.05e-1)" "unprognostic (4.58e-2)" "unprognostic (1.04e-1)" "unprognostic (4.04e-1)" "potential prognostic favorable (1.70e-7)" "unprognostic (3.79e-2)" "unprognostic (2.43e-2)" "unprognostic (1.04e-2)" "unprognostic (3.26e-1)" "unprognostic (1.50e-1)" "unprognostic (2.09e-1)" "unprognostic (9.09e-2)" "unprognostic (2.26e-1)" "unprognostic (1.54e-3)" "unprognostic (3.92e-2)" "unprognostic (2.18e-1)" "unprognostic (7.95e-2)" "unprognostic (1.11e-1)" "unprognostic (2.65e-1)" "unprognostic (6.55e-2)" "unprognostic (3.67e-1)" "unprognostic (6.10e-2)" "unprognostic (7.30e-2)" ABHD14A-ACY1 ENSG00000114786 "ABHD14A-ACY1 readthrough" 3 51974706-51989183 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Adipocytes: 4.6;Enterocytes: 9.4;Epicardial cells: 4.5;Hepatic stellate cells: 6.5;Retinal amacrine cells: 5.0;Retinal bipolar cells: 4.4;Retinal horizontal cells: 8.0;Rod photoreceptor cells: 7.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "HPA036174, HPA036175, HPA038153, HPA071834" Approved Supported Vesicles NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 35: Non-specific - DNA binding" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" Vesicles "HPA036174: , HPA036175: , HPA038153: , HPA071834: " "unprognostic (3.41e-2)" "unprognostic (4.19e-1)" "unprognostic (4.77e-2)" "unprognostic (8.32e-2)" "unprognostic (4.22e-1)" "unprognostic (2.94e-1)" ABHD14B "CIB, MGC15429" ENSG00000114779 "Abhydrolase domain containing 14B" Q96IU4 3 51968510-51983409 "Plasma proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 21.6;Cardiomyocytes: 47.3;Rod photoreceptor cells: 12.4;Tuft cells: 11.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036444, HPA036642" Supported Supported Nucleoplasm,Nucleoli,Cytosol NA NA 2300000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 76: Non-specific - Metabolism" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 2 "Nucleoplasm, Nucleoli" Cytosol "HPA036444: , HPA036642: " "unprognostic (1.43e-2)" "unprognostic (6.76e-2)" "unprognostic (2.14e-1)" "unprognostic (3.77e-2)" "unprognostic (2.00e-1)" "unprognostic (7.73e-2)" "unprognostic (3.04e-2)" "potential prognostic unfavorable (9.43e-5)" "unprognostic (5.78e-3)" "unprognostic (1.16e-1)" "potential prognostic favorable (2.68e-4)" "unprognostic (5.54e-2)" "potential prognostic favorable (9.72e-7)" "unprognostic (8.78e-3)" "potential prognostic favorable (3.62e-4)" "unprognostic (4.58e-2)" "unprognostic (5.39e-2)" "unprognostic (3.95e-2)" "unprognostic (1.68e-1)" "unprognostic (1.89e-1)" "unprognostic (4.49e-2)" "unprognostic (1.07e-1)" "unprognostic (6.14e-3)" "unprognostic (9.44e-3)" "unprognostic (1.03e-1)" "unprognostic (7.39e-2)" "unprognostic (1.71e-1)" "unprognostic (1.10e-1)" "unprognostic (2.26e-1)" "unprognostic (8.45e-2)" "unprognostic (1.62e-2)" ABHD15 ENSG00000168792 "Abhydrolase domain containing 15" Q6UXT9 17 29560547-29567037 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 34.7;Innate lymphoid cells: 52.0;NK-cells: 26.0;Pancreatic islet cells: 31.1;pDCs: 139.6" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 15.2;leukocyte: 13.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 18.2;MAIT T-cell: 6.6;NK-cell: 10.8;plasmacytoid DC: 23.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Pituitary gland - Thyrotropes, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA014470 Approved Approved Nucleoplasm,Cytosol "Secreted to blood" "No annotated function" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 39: Astrocytes - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 13 "Nucleoplasm, Cytosol" "HPA014470: " "unprognostic (1.83e-2)" "unprognostic (6.02e-2)" "unprognostic (2.64e-2)" "unprognostic (1.63e-1)" "unprognostic (8.05e-2)" "unprognostic (1.76e-1)" "unprognostic (1.02e-1)" "unprognostic (1.49e-1)" "unprognostic (3.01e-1)" "unprognostic (4.38e-2)" "unprognostic (7.71e-2)" "unprognostic (1.39e-1)" "unprognostic (3.91e-2)" "unprognostic (2.15e-1)" "unprognostic (6.14e-2)" "unprognostic (1.85e-2)" "unprognostic (1.55e-1)" "unprognostic (6.79e-2)" "unprognostic (1.08e-1)" "unprognostic (3.88e-2)" "unprognostic (2.52e-1)" "potential prognostic favorable (4.91e-4)" "unprognostic (2.08e-1)" "unprognostic (6.19e-2)" "unprognostic (1.02e-1)" "unprognostic (1.78e-1)" "unprognostic (5.43e-2)" "unprognostic (2.20e-2)" "unprognostic (2.63e-1)" "unprognostic (1.70e-1)" "unprognostic (2.28e-1)" ABHD16A "BAT5, D6S82E, NG26" ENSG00000204427 "Abhydrolase domain containing 16A, phospholipase" O95870 6 31686955-31703356 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 6 "Astrocytes: 14.6;Bergmann glia: 16.0;Brain excitatory neurons: 24.2;Brain inhibitory neurons: 21.2;Choroid plexus epithelial cells: 9.2;Ependymal cells: 17.0;Microglia: 20.5;Oligodendrocyte progenitor cells: 21.7;Oligodendrocytes: 24.3;Other brain neurons: 25.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058606 Approved NA NA 16000 "Cluster 14: Non-specific - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 98: Neurons - Neurotransmission & signaling" 54 "HPA058606: " "unprognostic (5.89e-2)" "unprognostic (1.89e-1)" "unprognostic (1.74e-1)" "unprognostic (4.70e-2)" "unprognostic (2.86e-1)" "unprognostic (4.60e-2)" "potential prognostic favorable (9.51e-8)" "unprognostic (3.84e-2)" "unprognostic (1.00e-1)" "unprognostic (6.51e-3)" "unprognostic (4.64e-2)" "unprognostic (1.88e-1)" "unprognostic (6.39e-3)" "unprognostic (3.75e-2)" "unprognostic (3.14e-1)" "unprognostic (2.13e-2)" "unprognostic (1.46e-1)" "unprognostic (9.20e-2)" "unprognostic (3.18e-1)" "unprognostic (1.24e-1)" "unprognostic (1.10e-1)" "unprognostic (1.52e-1)" "unprognostic (1.85e-1)" "unprognostic (1.31e-1)" "unprognostic (8.46e-2)" "unprognostic (2.64e-1)" "unprognostic (2.99e-1)" "unprognostic (9.41e-2)" "unprognostic (1.39e-2)" ABHD16B "C20orf135, dJ591C20.1" ENSG00000183260 "Abhydrolase domain containing 16B" Q9H3Z7 20 63861498-63862988 "Plasma proteins, Predicted intracellular proteins" "Lipid metabolism, Phospholipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "testis: 15.3" "Group enriched" "Detected in some" 10 "Early spermatids: 157.5;Late spermatids: 432.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 2.7" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA059272, HPA075886" Uncertain Enhanced Nucleoplasm NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 47: Testis - Mixed function" "Cluster 27: Non-specific - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" Nucleoplasm "HPA059272: , HPA075886: " "unprognostic (1.74e-1)" "unprognostic (4.97e-2)" "unprognostic (6.45e-2)" "unprognostic (1.45e-3)" "unprognostic (2.46e-1)" "unprognostic (7.08e-3)" "unprognostic (2.98e-1)" "potential prognostic favorable (4.16e-4)" "unprognostic (5.98e-2)" "unprognostic (5.81e-2)" "unprognostic (7.12e-2)" "unprognostic (1.66e-1)" "unprognostic (1.25e-1)" "unprognostic (1.68e-1)" "unprognostic (2.99e-2)" "unprognostic (6.65e-2)" "unprognostic (2.22e-2)" "unprognostic (3.17e-2)" "unprognostic (1.46e-1)" "unprognostic (2.94e-1)" "unprognostic (6.81e-2)" "potential prognostic favorable (2.34e-5)" "unprognostic (2.96e-1)" "unprognostic (2.89e-2)" "unprognostic (2.02e-1)" "unprognostic (8.39e-2)" "unprognostic (1.93e-2)" ABHD17A "C19orf27, FAM108A1, MGC5244" ENSG00000129968 "Abhydrolase domain containing 17A, depalmitoylase" Q96GS6 19 1876810-1885496 "Enzymes, Predicted intracellular proteins, Transporters" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 203.3" "Cell type enhanced" "Detected in many" "Megakaryocytes: 160.7;NK-cells: 150.7;Platelets: 175.6" "Cell type enhanced" "Detected in all" "leukocyte: 95.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043270, HPA047226, HPA069225" Uncertain Approved "Nuclear speckles,Vesicles" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 1 Vesicles "Nuclear speckles" "HPA043270: , HPA047226: , HPA069225: " "unprognostic (2.10e-2)" "unprognostic (2.86e-1)" "unprognostic (2.36e-3)" "unprognostic (1.79e-1)" "unprognostic (1.61e-2)" "unprognostic (1.01e-1)" "unprognostic (8.12e-3)" "unprognostic (4.34e-3)" "unprognostic (1.56e-1)" "unprognostic (9.20e-2)" "unprognostic (1.70e-2)" "unprognostic (7.58e-2)" "unprognostic (3.24e-2)" "unprognostic (1.51e-1)" "unprognostic (3.03e-1)" "unprognostic (1.83e-1)" "unprognostic (5.81e-2)" "unprognostic (2.38e-1)" "unprognostic (7.55e-2)" "unprognostic (3.14e-3)" "unprognostic (2.09e-1)" "unprognostic (2.68e-2)" "unprognostic (1.79e-1)" "unprognostic (5.72e-2)" "unprognostic (2.69e-2)" "unprognostic (1.54e-1)" "unprognostic (8.69e-2)" "unprognostic (1.73e-1)" "unprognostic (1.36e-1)" ABHD17B "C9orf77, CGI-67, FAM108B1" ENSG00000107362 "Abhydrolase domain containing 17B, depalmitoylase" Q5VST6 9 71862452-71911193 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 208.4;Rod photoreceptor cells: 434.7;Urothelial cells: 198.3" "Cell type enhanced" "Detected in all" "oligodendrocyte: 243.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047862 Uncertain NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 6: Leukemia - Signal transduction" "Cluster 79: Photoreceptor cells - Phototransduction" "HPA047862: " "unprognostic (3.01e-1)" "unprognostic (1.63e-2)" "unprognostic (3.18e-1)" "unprognostic (1.79e-2)" "unprognostic (5.45e-2)" "unprognostic (1.72e-2)" "unprognostic (5.95e-3)" "unprognostic (3.72e-3)" "unprognostic (2.72e-1)" "validated prognostic favorable (5.25e-7)" "validated prognostic favorable (3.01e-4)" "unprognostic (2.21e-1)" "unprognostic (9.17e-3)" "unprognostic (1.23e-1)" "unprognostic (1.71e-1)" "unprognostic (1.91e-1)" "unprognostic (9.20e-2)" "unprognostic (4.52e-2)" "unprognostic (4.07e-2)" "unprognostic (9.72e-2)" "unprognostic (2.45e-2)" "unprognostic (6.64e-2)" "unprognostic (2.35e-2)" "unprognostic (5.11e-3)" "unprognostic (1.19e-1)" "unprognostic (1.76e-1)" "unprognostic (2.83e-1)" "unprognostic (8.36e-2)" "unprognostic (2.66e-1)" ABHD17C FAM108C1 ENSG00000136379 "Abhydrolase domain containing 17C, depalmitoylase" Q6PCB6 15 80679684-80755621 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 61.2" "Cell type enhanced" "Detected in many" "Colonocytes: 235.3;Endometrial glandular cells: 155.7;Esophageal apical cells: 337.9;Foveolar cells: 245.3;Goblet cells: 222.9;Ocular epithelial cells: 155.9;Respiratory basal cells: 191.9;Urothelial cells: 153.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048890 Uncertain NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 29: Forebrain - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 12 "HPA048890: " "unprognostic (7.65e-3)" "unprognostic (5.44e-2)" "unprognostic (1.61e-1)" "unprognostic (3.71e-2)" "unprognostic (1.51e-1)" "unprognostic (3.90e-1)" "potential prognostic unfavorable (5.25e-4)" "unprognostic (1.31e-1)" "unprognostic (9.70e-3)" "unprognostic (3.08e-3)" "unprognostic (1.92e-3)" "unprognostic (4.85e-2)" "unprognostic (2.84e-2)" "unprognostic (3.50e-2)" "unprognostic (2.93e-1)" "unprognostic (2.25e-2)" "unprognostic (1.36e-1)" "unprognostic (1.06e-1)" "unprognostic (2.57e-2)" "unprognostic (1.22e-3)" "unprognostic (9.43e-2)" "unprognostic (1.74e-1)" "unprognostic (9.95e-2)" "unprognostic (1.96e-1)" "unprognostic (1.43e-1)" "unprognostic (4.73e-2)" "unprognostic (4.04e-1)" "unprognostic (5.36e-2)" "unprognostic (3.40e-1)" ABHD18 "C4orf29, FLJ21106" ENSG00000164074 "Abhydrolase domain containing 18" Q0P651 4 127965306-128039953 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050168, HPA051676" Approved Approved "Nuclear membrane" "Intracellular and membrane" "No annotated function" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 52: Non-specific - Cellular respiration" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 55: Myocytes - Oxidative muscle function" 4 "Nuclear membrane" "HPA050168: , HPA051676: " "unprognostic (3.19e-2)" "unprognostic (9.55e-2)" "unprognostic (3.43e-2)" "unprognostic (8.83e-2)" "unprognostic (1.39e-1)" "unprognostic (6.64e-2)" "unprognostic (1.91e-1)" "unprognostic (1.53e-1)" "unprognostic (1.68e-3)" "unprognostic (5.37e-3)" "potential prognostic favorable (7.17e-4)" "unprognostic (3.01e-2)" "unprognostic (9.39e-2)" "unprognostic (1.93e-2)" "unprognostic (7.22e-2)" "unprognostic (1.16e-2)" "unprognostic (5.90e-2)" "unprognostic (1.38e-1)" "unprognostic (2.81e-1)" "unprognostic (4.59e-2)" "unprognostic (2.47e-2)" "unprognostic (6.10e-3)" "potential prognostic favorable (5.22e-5)" "unprognostic (2.61e-1)" "unprognostic (9.02e-2)" "unprognostic (2.91e-2)" "unprognostic (1.72e-1)" "unprognostic (1.65e-2)" "unprognostic (2.26e-1)" ABHD2 LABH2 ENSG00000140526 "Abhydrolase domain containing 2, acylglycerol lipase" P08910 15 89087459-89202355 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 128.7" "Cell type enhanced" "Detected in many" "Foveolar cells: 670.3;Hepatocytes: 691.6;Late spermatids: 805.5;Neutrophils: 907.5;Oligodendrocyte progenitor cells: 642.0" "Cell type enhanced" "Detected in all" "oligodendrocyte precursor cell: 620.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 70.0;neutrophil: 52.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005999 Approved Approved "Nucleoplasm,Cytosol,Connecting piece,Flagellar centriole" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 29: Neutrophils - Innate immune cellular maintenance" "Cytosol, Flagellar centriole" "Nucleoplasm, Connecting piece" "HPA005999: " "unprognostic (1.20e-1)" "unprognostic (1.27e-1)" "unprognostic (2.72e-1)" "unprognostic (5.46e-2)" "unprognostic (4.66e-2)" "unprognostic (7.51e-3)" "unprognostic (9.35e-2)" "unprognostic (1.69e-2)" "unprognostic (5.28e-2)" "unprognostic (3.15e-2)" "validated prognostic favorable (1.47e-6)" "validated prognostic favorable (3.89e-4)" "unprognostic (3.05e-2)" "unprognostic (1.64e-1)" "unprognostic (2.72e-2)" "unprognostic (4.34e-2)" "unprognostic (2.58e-1)" "unprognostic (5.96e-2)" "unprognostic (5.43e-2)" "unprognostic (3.77e-3)" "potential prognostic unfavorable (1.75e-4)" "unprognostic (2.23e-3)" "unprognostic (1.12e-1)" "unprognostic (5.67e-2)" "unprognostic (1.85e-1)" "unprognostic (3.26e-1)" "unprognostic (3.00e-1)" "unprognostic (1.82e-1)" "unprognostic (4.45e-2)" "unprognostic (1.06e-2)" "unprognostic (1.89e-1)" ABHD3 LABH3 ENSG00000158201 "Abhydrolase domain containing 3, phospholipase" Q8WU67 18 21650901-21704780 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Phospholipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 61.7" "Cell type enhanced" "Detected in many" "Colonocytes: 425.4;Endometrial luminal cells: 513.7;Epididymal clear cells: 518.5;Esophageal apical cells: 462.3;Myonuclei: 655.4;Neutrophils: 487.7;Pancreatic duct cells: 464.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010729 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 77: Intestine - Digestion" "Cluster 44: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 24: Neutrophils - Innate immunity signal integration" 6 "Nucleoplasm, Plasma membrane" Vesicles "HPA010729: " "unprognostic (1.90e-1)" "unprognostic (1.49e-1)" "unprognostic (2.02e-1)" "unprognostic (6.95e-2)" "unprognostic (2.36e-2)" "unprognostic (1.26e-2)" "unprognostic (6.97e-2)" "unprognostic (1.82e-1)" "unprognostic (8.59e-3)" "unprognostic (4.94e-2)" "unprognostic (2.27e-2)" "unprognostic (4.94e-2)" "unprognostic (1.64e-1)" "potential prognostic unfavorable (6.32e-4)" "unprognostic (1.86e-2)" "unprognostic (2.85e-2)" "unprognostic (1.27e-3)" "unprognostic (2.17e-1)" "unprognostic (2.10e-1)" "unprognostic (1.30e-1)" "unprognostic (3.32e-2)" "unprognostic (9.29e-2)" "unprognostic (2.24e-1)" "unprognostic (2.63e-1)" "unprognostic (9.31e-2)" "unprognostic (7.27e-2)" "unprognostic (6.80e-3)" "unprognostic (1.26e-1)" "unprognostic (1.94e-1)" "unprognostic (8.11e-2)" "potential prognostic unfavorable (4.96e-4)" ABHD4 FLJ12816 ENSG00000100439 "Abhydrolase domain containing 4, N-acyl phospholipase B" Q8TB40 14 22598290-22612963 "Enzymes, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 42.9;Megakaryocyte progenitors: 51.6;Platelets: 125.7;Syncytiotrophoblasts: 40.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 39.4" "Lineage enriched" "Detected in all" 4 "granulocytes: 39.4" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Mitotic cells (Minor salivary gland), Prostate - Smooth muscle cells, Stomach - Gastric mucous cells, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000600 Uncertain Approved Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 9 Nucleoplasm "HPA000600: " "unprognostic (2.11e-1)" "unprognostic (2.89e-1)" "unprognostic (3.54e-1)" "unprognostic (2.27e-1)" "unprognostic (1.46e-1)" "unprognostic (3.44e-3)" "unprognostic (2.12e-2)" "unprognostic (1.67e-1)" "unprognostic (4.71e-2)" "unprognostic (7.00e-2)" "unprognostic (3.21e-2)" "unprognostic (4.62e-2)" "unprognostic (2.16e-3)" "unprognostic (7.74e-3)" "unprognostic (2.16e-1)" "unprognostic (1.23e-3)" "unprognostic (4.17e-2)" "unprognostic (7.16e-2)" "unprognostic (2.46e-1)" "unprognostic (2.35e-2)" "unprognostic (2.27e-2)" "unprognostic (5.45e-3)" "unprognostic (2.82e-1)" "unprognostic (3.81e-1)" "potential prognostic unfavorable (8.17e-4)" "unprognostic (1.82e-1)" "unprognostic (2.80e-1)" "unprognostic (1.87e-1)" "unprognostic (1.83e-1)" "unprognostic (2.38e-1)" "unprognostic (2.81e-1)" ABHD5 "CGI-58, NCIE2" ENSG00000011198 "Abhydrolase domain containing 5, lysophosphatidic acid acyltransferase" Q8WTS1 3 43690108-43734371 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Differentiation, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Cataract, Deafness, Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 763.3;Neutrophil progenitors: 1162.9;Neutrophils: 2098.3;Syncytiotrophoblasts: 685.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 68.2;neutrophil: 42.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 68.2" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Kidney - Endothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Spleen - Neutrophils_2, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020685, HPA035851, HPA035852" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 58: Skin - Keratinization" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 20 "Vesicles, Cytosol" Nucleoplasm "CAB020685: , HPA035851: , HPA035852: " "unprognostic (3.68e-3)" "unprognostic (1.88e-1)" "unprognostic (1.44e-2)" "unprognostic (3.41e-1)" "unprognostic (1.16e-2)" "unprognostic (1.47e-1)" "unprognostic (2.86e-2)" "unprognostic (9.16e-3)" "unprognostic (1.10e-1)" "unprognostic (1.54e-2)" "potential prognostic favorable (1.11e-4)" "unprognostic (2.68e-1)" "unprognostic (2.17e-3)" "unprognostic (4.52e-2)" "unprognostic (1.35e-1)" "unprognostic (4.19e-2)" "unprognostic (1.89e-1)" "unprognostic (2.11e-1)" "unprognostic (5.55e-2)" "unprognostic (3.13e-3)" "unprognostic (1.41e-1)" "unprognostic (2.93e-2)" "unprognostic (1.10e-1)" "unprognostic (1.73e-2)" "unprognostic (1.99e-1)" "unprognostic (2.80e-1)" "unprognostic (7.49e-2)" "unprognostic (5.88e-2)" "unprognostic (2.14e-1)" "unprognostic (1.92e-2)" "unprognostic (1.43e-1)" ABHD6 ENSG00000163686 "Abhydrolase domain containing 6, acylglycerol lipase" Q9BV23 3 58237532-58295693 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 60.7" "Cell type enhanced" "Detected in many" "Corticotrophs: 152.0;Enterocytes: 136.7;Hepatocytes: 93.1;Lactotrophs: 85.3;Oligodendrocytes: 117.7;Proximal tubule cells: 158.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Bone cancer: 53.5" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017283, HPA073225" Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 88: Proximal tubular cells - Transmembrane transport" 6 Vesicles Nucleoplasm "HPA017283: , HPA073225: " "unprognostic (9.31e-3)" "unprognostic (1.16e-1)" "unprognostic (2.25e-2)" "unprognostic (1.78e-1)" "unprognostic (2.25e-3)" "unprognostic (3.46e-2)" "unprognostic (2.22e-2)" "potential prognostic favorable (2.16e-5)" "unprognostic (1.95e-1)" "unprognostic (2.08e-1)" "validated prognostic favorable (1.72e-8)" "validated prognostic favorable (4.84e-6)" "potential prognostic favorable (3.08e-5)" "unprognostic (1.25e-1)" "unprognostic (6.73e-3)" "unprognostic (4.72e-3)" "unprognostic (2.72e-3)" "unprognostic (2.30e-1)" "unprognostic (1.86e-1)" "unprognostic (3.44e-3)" "unprognostic (7.03e-2)" "unprognostic (3.74e-3)" "unprognostic (1.66e-2)" "unprognostic (1.09e-1)" "unprognostic (4.80e-2)" "unprognostic (1.37e-1)" "unprognostic (7.26e-2)" "unprognostic (5.29e-2)" "unprognostic (2.24e-2)" "unprognostic (3.70e-1)" "unprognostic (1.30e-1)" ABHD8 "FLJ11743, MGC14280, MGC2512" ENSG00000127220 "Abhydrolase domain containing 8" Q96I13 19 17292131-17310236 "Predicted intracellular proteins" "Inflammatory response" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 99.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 254.7;Early spermatids: 147.5;Late primary spermatocytes: 201.8;Late spermatids: 496.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Skin - Keratinocyte (granular), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037658, HPA058209" Approved Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 23: Non-specific - Transcription" "Cluster 65: Non-specific - Cell growth & division" 1 Nucleoplasm "Nuclear bodies" "HPA037658: , HPA058209: " "unprognostic (1.09e-1)" "unprognostic (6.56e-2)" "unprognostic (6.25e-2)" "unprognostic (2.63e-1)" "unprognostic (2.85e-3)" "unprognostic (2.09e-1)" "unprognostic (5.73e-2)" "unprognostic (5.12e-2)" "unprognostic (1.85e-2)" "unprognostic (1.61e-1)" "unprognostic (1.36e-2)" "unprognostic (1.03e-1)" "unprognostic (2.87e-1)" "unprognostic (3.26e-3)" "unprognostic (6.77e-2)" "unprognostic (8.04e-2)" "unprognostic (3.16e-1)" "unprognostic (1.52e-1)" "unprognostic (1.16e-2)" "unprognostic (1.13e-1)" "unprognostic (2.45e-1)" "potential prognostic favorable (3.54e-5)" "unprognostic (1.00e-1)" "unprognostic (6.45e-2)" "unprognostic (4.60e-3)" "unprognostic (1.30e-1)" "unprognostic (7.49e-2)" "unprognostic (6.54e-2)" "unprognostic (2.50e-1)" "unprognostic (2.77e-1)" "unprognostic (1.85e-2)" ABI1 "ABI-1, E3B1, SSH3BP1" ENSG00000136754 "Abl interactor 1" Q8IZP0 10 26746593-26861087 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 761.7;Neutrophils: 770.9;Ocular epithelial cells: 729.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008375, HPA068407" Approved Approved "Plasma membrane,Cell Junctions" NA NA 330000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 29: Forebrain - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 100: Stratified epithelial cells - Barrier functions" 63 "Plasma membrane, Cell Junctions" "CAB008375: , HPA068407: " "unprognostic (9.39e-2)" "unprognostic (3.41e-2)" "unprognostic (2.10e-1)" "unprognostic (6.65e-3)" "unprognostic (1.61e-1)" "potential prognostic unfavorable (3.90e-4)" "unprognostic (5.90e-2)" "potential prognostic favorable (1.27e-5)" "unprognostic (2.54e-2)" "unprognostic (1.58e-2)" "potential prognostic favorable (1.75e-7)" "unprognostic (2.69e-2)" "unprognostic (1.63e-1)" "potential prognostic unfavorable (6.36e-4)" "unprognostic (4.18e-2)" "unprognostic (1.64e-1)" "unprognostic (2.87e-1)" "unprognostic (1.56e-1)" "unprognostic (6.11e-2)" "unprognostic (1.73e-2)" "potential prognostic unfavorable (1.10e-4)" "unprognostic (1.40e-2)" "unprognostic (3.10e-1)" "unprognostic (6.20e-2)" "unprognostic (1.52e-1)" "unprognostic (1.03e-1)" "unprognostic (1.01e-1)" "unprognostic (3.09e-1)" "unprognostic (1.57e-1)" "unprognostic (8.91e-2)" "unprognostic (3.00e-1)" ABI2 "ABI-2, ABI2B, AblBP3, AIP-1, argBPIA, SSH3BP2" ENSG00000138443 "Abl interactor 2" Q9NYB9 2 203328280-203447728 "Predicted intracellular proteins" "Host-virus interaction, Neurogenesis" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Bergmann glia: 466.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Pancreas - Endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070567 Enhanced Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 65: Brain - Transcription" "Cluster 33: Neurons - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 167 Nucleoplasm "Vesicles, Cytosol" "HPA070567: " "unprognostic (1.12e-1)" "unprognostic (1.61e-1)" "unprognostic (1.37e-1)" "unprognostic (5.27e-2)" "unprognostic (1.56e-1)" "unprognostic (1.95e-1)" "unprognostic (1.49e-1)" "unprognostic (2.12e-1)" "unprognostic (2.23e-2)" "unprognostic (2.44e-2)" "potential prognostic favorable (9.19e-5)" "unprognostic (1.06e-3)" "unprognostic (8.45e-3)" "potential prognostic unfavorable (2.89e-4)" "unprognostic (5.20e-2)" "unprognostic (3.13e-1)" "unprognostic (1.70e-2)" "unprognostic (1.24e-2)" "unprognostic (1.77e-1)" "unprognostic (1.96e-1)" "unprognostic (1.58e-1)" "unprognostic (1.49e-1)" "unprognostic (8.45e-2)" "unprognostic (2.73e-1)" "unprognostic (3.52e-1)" "unprognostic (4.31e-3)" "unprognostic (1.53e-1)" "unprognostic (4.25e-2)" "unprognostic (3.24e-1)" "unprognostic (1.26e-1)" "unprognostic (2.12e-1)" ABI3 "NESH, SSH3BP3" ENSG00000108798 "ABI family member 3" Q9P2A4 17 49210411-49223225 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 74.8" "Cell type enhanced" "Detected in some" "cDC: 45.7;Kupffer cells: 124.0;Lymphatic endothelial cells: 25.4;Macrophages: 68.0;Microglia: 33.7;monocytes: 62.9;NK-cells: 80.5;T-cells: 41.3;Vascular endothelial cells: 40.2" "Group enriched" "Detected in some" 8 "central nervous system macrophage: 45.6;leukocyte: 40.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "intermediate monocyte: 735.3;non-classical monocyte: 792.7" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 10.7;lymphoma: 30.4" "Adrenal gland - Macrophages, Heart muscle - Endothelial cells, Spleen - Macrophages" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA017345, HPA064805" Enhanced NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 57 "HPA017345: , HPA064805: " "unprognostic (1.78e-1)" "unprognostic (6.06e-2)" "unprognostic (2.97e-2)" "unprognostic (1.06e-2)" "unprognostic (6.81e-2)" "unprognostic (2.74e-2)" "unprognostic (7.73e-2)" "unprognostic (8.84e-2)" "unprognostic (2.83e-3)" "unprognostic (1.57e-1)" "potential prognostic favorable (1.23e-4)" "unprognostic (1.98e-2)" "unprognostic (3.92e-1)" "unprognostic (1.42e-1)" "unprognostic (4.05e-2)" "unprognostic (1.76e-2)" "unprognostic (3.80e-3)" "unprognostic (3.32e-1)" "unprognostic (7.24e-2)" "unprognostic (1.24e-1)" "unprognostic (2.96e-1)" "unprognostic (2.30e-2)" "unprognostic (1.42e-2)" "unprognostic (3.30e-2)" "unprognostic (3.64e-1)" "unprognostic (1.93e-2)" "unprognostic (2.27e-1)" "unprognostic (2.16e-1)" "unprognostic (2.03e-2)" "unprognostic (9.46e-2)" "unprognostic (1.64e-1)" ABI3BP "DKFZP586L2024, NESHBP, TARSH" ENSG00000154175 "ABI family member 3 binding protein" Q7Z7G0 3 100749156-100993515 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 259.7;Cardiomyocytes: 371.6;Ependymal cells: 201.3;Epicardial cells: 343.4;Fibro-adipogenic progenitors: 732.4;Fibroblasts: 487.9;Leydig cells: 364.3;Lymphatic endothelial cells: 214.3;Mesothelial cells: 260.7;Müller glia: 395.8;Myosatellite cells: 200.9" "Cell type enhanced" "Detected in all" "astrocyte: 183.0;ependymal cell: 179.2" "Cancer enhanced" "Detected in all" "Kidney Renal Papillary Cell Carcinoma (TCGA): 61.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 43.0;thyroid cancer: 49.9" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Minor Salivary Gland - Fibroblasts, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Group enriched" "Detected in many" 4 "amygdala: 4.2;basal ganglia: 15.9;cerebellum: 5.5;cerebral cortex: 13.9;olfactory bulb: 12.0" "Low region specificity" "Detected in all" HPA044127 Uncertain "Secreted in other tissues" "No annotated function" NA NA 84000000 "Cluster 13: Lung - Secretion" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" "HPA044127: " "unprognostic (6.32e-2)" "unprognostic (1.74e-1)" "unprognostic (1.25e-2)" "unprognostic (1.49e-2)" "unprognostic (1.09e-1)" "unprognostic (1.89e-1)" "unprognostic (1.74e-1)" "unprognostic (4.31e-2)" "unprognostic (6.78e-2)" "unprognostic (1.55e-2)" "potential prognostic favorable (3.95e-7)" "unprognostic (1.95e-1)" "unprognostic (2.59e-3)" "unprognostic (4.39e-1)" "unprognostic (1.38e-1)" "unprognostic (3.08e-3)" "unprognostic (2.14e-2)" "unprognostic (1.47e-2)" "unprognostic (2.17e-1)" "unprognostic (3.17e-2)" "unprognostic (2.08e-2)" "unprognostic (2.61e-2)" "unprognostic (5.02e-1)" "unprognostic (7.49e-2)" "unprognostic (5.31e-2)" "unprognostic (1.20e-1)" "unprognostic (1.86e-1)" "unprognostic (1.88e-2)" "unprognostic (5.08e-2)" "unprognostic (2.01e-2)" "unprognostic (7.63e-3)" ABITRAM "C9orf6, CG-8, FAM206A, FLJ20457, Simiate" ENSG00000119328 "Actin binding transcription modulator" Q9NX38 9 108934400-108950744 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epicardial cells: 127.4;Respiratory ciliated cells: 63.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035917, HPA035918" Uncertain Approved "Nucleoplasm,Kinetochore,Cytokinetic bridge,Mitotic spindle,Primary cilium,Primary cilium tip,Cytosol" Yes No "Cluster 10: Non-specific - Membrane trafficking" "Cluster 22: Epididymis - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 9 "Nucleoplasm, Cytosol" "Kinetochore, Cytokinetic bridge, Mitotic spindle, Primary cilium, Primary cilium tip" "HPA035917: , HPA035918: " "unprognostic (1.39e-1)" "unprognostic (1.27e-2)" "unprognostic (6.29e-2)" "unprognostic (1.20e-1)" "unprognostic (1.58e-2)" "unprognostic (3.17e-1)" "unprognostic (3.29e-3)" "unprognostic (4.38e-3)" "unprognostic (1.11e-2)" "potential prognostic favorable (3.10e-4)" "unprognostic (2.88e-1)" "unprognostic (6.05e-2)" "potential prognostic unfavorable (2.46e-4)" "unprognostic (2.47e-2)" "unprognostic (1.10e-1)" "unprognostic (1.28e-1)" "unprognostic (1.64e-1)" "unprognostic (2.08e-1)" "unprognostic (1.24e-1)" "unprognostic (5.72e-2)" "unprognostic (8.41e-2)" "unprognostic (6.50e-2)" "unprognostic (7.74e-2)" "unprognostic (2.31e-2)" "unprognostic (3.55e-1)" "unprognostic (9.01e-2)" "unprognostic (2.90e-1)" "unprognostic (5.73e-2)" "unprognostic (1.50e-2)" ABL1 "ABL, c-ABL, JTK7, p150" ENSG00000097007 "ABL proto-oncogene 1, non-receptor tyrosine kinase" P00519 9 130713043-130887675 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Autophagy, Cell adhesion, DNA damage, DNA repair, Endocytosis" "DNA-binding, Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002686, HPA027251, HPA027280, HPA028409" Supported Supported "Nucleoplasm,Nuclear bodies" Yes No "Cluster 30: Non-specific - DNA binding" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 6: Non-specific - Immune response" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 103: Non-specific - Basic cellular processes" 162 Nucleoplasm "Nuclear bodies" "CAB002686: , HPA027251: , HPA027280: , HPA028409: " "unprognostic (1.53e-1)" "unprognostic (2.66e-2)" "unprognostic (4.09e-1)" "unprognostic (1.27e-2)" "unprognostic (1.56e-1)" "unprognostic (1.40e-2)" "unprognostic (6.41e-2)" "unprognostic (3.49e-2)" "unprognostic (2.96e-1)" "unprognostic (2.22e-1)" "potential prognostic favorable (2.76e-4)" "unprognostic (7.92e-3)" "unprognostic (4.17e-1)" "unprognostic (7.37e-3)" "unprognostic (5.27e-2)" "unprognostic (2.14e-2)" "unprognostic (7.30e-2)" "unprognostic (1.14e-2)" "unprognostic (3.64e-3)" "unprognostic (1.42e-2)" "unprognostic (2.99e-3)" "unprognostic (9.06e-2)" "unprognostic (3.81e-1)" "unprognostic (1.44e-1)" "unprognostic (2.60e-2)" "unprognostic (1.17e-1)" "unprognostic (1.58e-1)" "unprognostic (7.66e-2)" "unprognostic (3.38e-1)" "unprognostic (9.73e-2)" "unprognostic (3.41e-2)" ABL2 "ABLL, ARG" ENSG00000143322 "ABL proto-oncogene 2, non-receptor tyrosine kinase" P42684 1 179099330-179229684 "Cancer-related genes, Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Cell adhesion" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Schwann cells: 418.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells, Prostate - Endothelial cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001866, CAB017106, HPA072754" Uncertain Approved "Intermediate filaments,Cytosol" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 33: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 37 Cytosol "Intermediate filaments" "CAB017106: , HPA001866: , HPA072754: " "unprognostic (1.38e-1)" "unprognostic (6.50e-2)" "potential prognostic favorable (3.49e-5)" "potential prognostic unfavorable (4.55e-4)" "unprognostic (1.14e-1)" "unprognostic (3.23e-1)" "unprognostic (2.65e-1)" "unprognostic (1.31e-2)" "unprognostic (9.01e-3)" "unprognostic (1.36e-2)" "unprognostic (4.56e-2)" "unprognostic (5.43e-2)" "unprognostic (3.81e-3)" "unprognostic (2.67e-2)" "unprognostic (1.09e-1)" "unprognostic (6.65e-3)" "unprognostic (2.24e-3)" "unprognostic (1.02e-1)" "unprognostic (3.74e-1)" "unprognostic (8.55e-2)" "unprognostic (6.26e-3)" "unprognostic (4.31e-2)" "potential prognostic unfavorable (5.35e-7)" "unprognostic (1.70e-1)" "unprognostic (2.49e-1)" "unprognostic (4.12e-2)" "unprognostic (1.95e-1)" "unprognostic (5.89e-2)" "unprognostic (1.59e-1)" "unprognostic (2.24e-2)" "unprognostic (6.00e-2)" ABLIM1 "ABLIM, LIMAB1, limatin" ENSG00000099204 "Actin binding LIM protein 1" O14639 10 114431112-114768061 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 1542.4;Astrocytes: 1411.4;Cardiomyocytes: 2310.0;Esophageal apical cells: 2696.5" "Cell type enhanced" "Detected in all" "astrocyte: 1712.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 139.3" "Group enriched" "Detected in many" 9 "B-cells: 52.3;NK-cells: 63.7;T-cells: 139.3" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 1, Spleen - B-cells (Spleen), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038951, HPA038952" Approved Approved "Cytosol,Connecting piece,Mid piece" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 35: Non-specific - Mixed function" "Cluster 35: Non-specific - DNA binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 35 Cytosol "Connecting piece, Mid piece" "HPA038951: , HPA038952: " "unprognostic (5.20e-3)" "unprognostic (4.68e-3)" "unprognostic (6.88e-2)" "unprognostic (1.94e-1)" "unprognostic (1.66e-1)" "unprognostic (2.46e-2)" "unprognostic (3.43e-3)" "unprognostic (9.79e-2)" "unprognostic (5.34e-3)" "unprognostic (2.99e-1)" "validated prognostic favorable (4.81e-7)" "validated prognostic favorable (6.21e-6)" "unprognostic (6.02e-3)" "unprognostic (6.22e-2)" "unprognostic (3.01e-1)" "unprognostic (2.94e-1)" "unprognostic (2.85e-1)" "unprognostic (3.57e-1)" "unprognostic (1.94e-1)" "unprognostic (1.83e-2)" "unprognostic (3.20e-2)" "unprognostic (2.74e-2)" "unprognostic (2.06e-2)" "unprognostic (1.61e-1)" "unprognostic (5.68e-2)" "unprognostic (8.57e-2)" "unprognostic (6.56e-3)" "unprognostic (1.53e-1)" "unprognostic (1.56e-1)" "unprognostic (3.93e-1)" "unprognostic (5.26e-2)" ABLIM2 KIAA1808 ENSG00000163995 "Actin binding LIM protein family member 2" Q6H8Q1 4 7965310-8158832 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "skeletal muscle: 188.4;tongue: 68.6" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 291.1;Myonuclei: 668.2;Podocytes: 1220.0;Retinal ganglion cells: 212.5;Retinal horizontal cells: 256.4;Thymic myoid cells: 1249.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells, Kidney - Podocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035808 Uncertain Uncertain Nucleoplasm,Mitochondria NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 53: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 1 Mitochondria Nucleoplasm "HPA035808: " "unprognostic (4.00e-3)" "unprognostic (5.16e-2)" "unprognostic (1.02e-3)" "unprognostic (3.56e-3)" "unprognostic (3.42e-2)" "unprognostic (3.99e-2)" "unprognostic (2.40e-2)" "unprognostic (7.64e-2)" "unprognostic (1.01e-1)" "potential prognostic favorable (7.69e-4)" "unprognostic (2.90e-2)" "unprognostic (4.78e-2)" "unprognostic (1.21e-2)" "unprognostic (9.97e-3)" "unprognostic (2.38e-1)" "unprognostic (4.12e-3)" "unprognostic (1.24e-2)" "potential prognostic unfavorable (1.25e-4)" "unprognostic (1.23e-2)" "unprognostic (1.32e-1)" "unprognostic (1.02e-2)" "unprognostic (1.50e-2)" "unprognostic (5.31e-2)" "unprognostic (5.97e-3)" "unprognostic (4.18e-2)" "unprognostic (2.72e-3)" "unprognostic (1.98e-1)" "unprognostic (2.39e-2)" "unprognostic (1.06e-1)" ABLIM3 KIAA0843 ENSG00000173210 "Actin binding LIM protein family member 3" O94929 5 149141483-149260542 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 109.5" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 827.2;Hepatocytes: 339.9;Lymphatic endothelial cells: 129.4;Platelets: 161.9;Proximal tubule cells: 143.0;Rod photoreceptor cells: 790.2;Urothelial cells: 144.2;Vascular endothelial cells: 186.0" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 36.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 43.8" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Kidney - Proximal tubular cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002472, HPA003245" Approved Uncertain Nucleoplasm,Cytosol NA NA 5500 "Cluster 4: Neutrophils - Degranulation" "Cluster 76: Non-specific - Metabolism" "Cluster 25: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 79: Photoreceptor cells - Phototransduction" 3 Nucleoplasm Cytosol "HPA002472: , HPA003245: " "unprognostic (4.79e-2)" "unprognostic (1.35e-1)" "unprognostic (6.78e-2)" "unprognostic (1.10e-3)" "unprognostic (5.27e-2)" "potential prognostic unfavorable (9.95e-4)" "unprognostic (7.44e-2)" "unprognostic (2.37e-1)" "unprognostic (5.31e-2)" "unprognostic (5.37e-2)" "potential prognostic favorable (1.66e-5)" "unprognostic (2.59e-2)" "unprognostic (1.52e-1)" "unprognostic (1.88e-2)" "unprognostic (1.88e-1)" "unprognostic (3.88e-2)" "unprognostic (1.36e-1)" "potential prognostic unfavorable (3.96e-5)" "unprognostic (6.35e-3)" "unprognostic (1.02e-1)" "unprognostic (6.22e-3)" "unprognostic (4.59e-3)" "unprognostic (2.43e-1)" "unprognostic (3.30e-1)" "unprognostic (7.36e-2)" "unprognostic (1.31e-1)" "unprognostic (2.95e-2)" "unprognostic (2.51e-1)" "unprognostic (1.85e-3)" "unprognostic (5.43e-2)" ABO "A3GALNT, A3GALT1" ENSG00000175164 "ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase" 9 133233278-133276024 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "ovary: 14.1" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 34.2;Distal convoluted tubule cells: 30.6;Loop of henle epithelial cells: 62.0;Papillary tip epithelial cells: 112.5;Platelets: 35.2;Proximal tubule cells: 59.1;Renal collecting duct intercalated cells: 88.6;Renal collecting duct principal cells: 120.0;Renal connecting tubule cells: 102.4" "Cell type enhanced" "Detected in many" "pericyte: 115.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 2.1;naive B-cell: 2.1" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in many" 7 "Gallbladder cancer: 91.2" "Liver - Vascular endothelial cells" "Not detected" "Not detected" "Secreted to blood" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 75: Ovary - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" "unprognostic (3.65e-1)" "unprognostic (8.82e-2)" "unprognostic (2.08e-1)" "unprognostic (2.11e-1)" "unprognostic (2.73e-1)" "unprognostic (3.23e-2)" "unprognostic (1.63e-2)" "unprognostic (1.57e-1)" "unprognostic (1.08e-1)" "potential prognostic favorable (6.28e-4)" "unprognostic (6.56e-2)" "unprognostic (1.20e-1)" "unprognostic (1.62e-1)" "unprognostic (2.11e-2)" "unprognostic (7.94e-2)" "unprognostic (9.05e-2)" "unprognostic (2.31e-3)" "unprognostic (6.35e-3)" "unprognostic (2.19e-1)" "unprognostic (1.46e-2)" "unprognostic (2.84e-1)" "unprognostic (3.87e-1)" "unprognostic (2.54e-1)" "unprognostic (5.93e-2)" "unprognostic (1.35e-2)" "unprognostic (3.25e-2)" "unprognostic (1.01e-1)" "unprognostic (7.34e-2)" "unprognostic (1.22e-1)" ABR MDB ENSG00000159842 "ABR activator of RhoGEF and GTPase" Q12979 17 1003519-1229738 "Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 101.3" "Cell type enhanced" "Detected in many" "Astrocytes: 284.4;Bergmann glia: 146.8;Brain inhibitory neurons: 107.5;Ependymal cells: 132.3;Epicardial cells: 177.4;Macrophages: 121.2;Microglia: 900.3;monocytes: 124.4;Other brain neurons: 108.8;Renal collecting duct intercalated cells: 115.2" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 1131.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 14 "basophil: 9.0" "Lineage enriched" "Detected in single" 15 "granulocytes: 9.0" "Low cancer specificity" "Detected in many" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053618, HPA054824" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 51: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 3 Cytosol Nucleoplasm "HPA053618: , HPA054824: " "unprognostic (4.17e-3)" "unprognostic (1.15e-1)" "unprognostic (4.00e-1)" "unprognostic (1.21e-2)" "unprognostic (1.31e-1)" "unprognostic (1.21e-1)" "unprognostic (1.41e-1)" "unprognostic (3.46e-2)" "unprognostic (1.11e-1)" "unprognostic (1.63e-2)" "unprognostic (1.31e-2)" "unprognostic (1.75e-1)" "unprognostic (1.58e-1)" "unprognostic (6.98e-2)" "unprognostic (2.70e-2)" "unprognostic (1.63e-1)" "unprognostic (1.40e-3)" "unprognostic (3.52e-2)" "unprognostic (1.60e-3)" "unprognostic (3.29e-2)" "unprognostic (2.11e-2)" "unprognostic (1.45e-2)" "unprognostic (1.59e-1)" "unprognostic (1.20e-2)" "unprognostic (4.92e-2)" "unprognostic (2.72e-1)" "unprognostic (7.28e-2)" "unprognostic (2.08e-1)" "unprognostic (2.51e-2)" "unprognostic (3.70e-1)" ABRA STARS ENSG00000174429 "Actin binding Rho activating protein" Q8N0Z2 8 106759483-106770244 "Predicted intracellular proteins" "Protein transport, Transcription, Transcription regulation, Translocation, Transport" "Actin-binding, Activator" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 29.5;skeletal muscle: 135.7;tongue: 59.6" "Group enriched" "Detected in some" 5 "Early spermatids: 79.4;Late primary spermatocytes: 158.3;Myonuclei: 121.8;Thymic myoid cells: 134.6" "Cell type enhanced" "Detected in some" "upper rhombic lip: 1.7;vascular associated smooth muscle cell: 1.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 241 "Rhabdoid: 26.3" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Smooth muscle cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 2: Neurons - Nucleosome" "Cluster 5: Rhabdoid - Unknown function" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 4 ABRACL "C6orf115, Costars, HSPC280, PRO2013" ENSG00000146386 "ABRA C-terminal like" Q9P1F3 6 139028745-139043302 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 266.9;Esophageal apical cells: 500.1;Extravillous trophoblasts: 298.0;Gastric progenitor cells: 292.2;Hepatocytes: 292.3;Hofbauer cells: 469.7;Kupffer cells: 439.7;Megakaryocytes: 933.4" "Cell type enhanced" "Detected in many" "leukocyte: 44.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Kidney - Proximal tubular cells, Skin - Outer root sheath cells, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030217 Enhanced Approved Nucleoplasm,Cytosol NA NA 7300000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 51: Neurons - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 47: Platelets - Hemostasis" Nucleoplasm Cytosol "HPA030217: " "unprognostic (3.10e-2)" "unprognostic (2.49e-3)" "unprognostic (1.43e-1)" "unprognostic (7.47e-2)" "unprognostic (4.83e-2)" "unprognostic (4.56e-2)" "unprognostic (8.21e-2)" "unprognostic (2.21e-1)" "unprognostic (6.08e-3)" "unprognostic (2.59e-2)" "unprognostic (1.65e-3)" "unprognostic (1.04e-1)" "unprognostic (3.49e-3)" "unprognostic (3.96e-2)" "unprognostic (1.81e-2)" "unprognostic (9.69e-2)" "unprognostic (1.51e-1)" "unprognostic (5.30e-2)" "unprognostic (2.34e-2)" "unprognostic (5.71e-2)" "potential prognostic unfavorable (4.46e-4)" "unprognostic (1.57e-1)" "unprognostic (2.65e-2)" "unprognostic (2.63e-2)" "unprognostic (1.13e-1)" "unprognostic (1.24e-2)" "unprognostic (5.45e-2)" "unprognostic (2.34e-2)" "unprognostic (3.49e-1)" ABRAXAS1 "ABRA1, ABRAXAS, CCDC98, FAM175A, FLJ13614" ENSG00000163322 "Abraxas 1, BRCA1 A complex subunit" Q6UWZ7 4 83459517-83523348 "Disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "Chromatin regulator" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 80.4;Differentiating spermatogonia: 113.0;Early primary spermatocytes: 149.4;Early spermatids: 86.4;Late primary spermatocytes: 80.3" "Cell type enriched" "Detected in all" 4 "choroid plexus epithelial cell: 109.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037654 Uncertain Supported "Nuclear bodies" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 75: Ovary - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 25: Non-specific - Ribosome" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 17 "Nuclear bodies" "HPA037654: " "unprognostic (2.85e-2)" "unprognostic (2.74e-2)" "unprognostic (3.33e-2)" "unprognostic (7.95e-2)" "unprognostic (1.71e-1)" "unprognostic (2.71e-2)" "unprognostic (9.20e-2)" "unprognostic (1.27e-1)" "unprognostic (6.95e-2)" "validated prognostic favorable (4.38e-7)" "validated prognostic favorable (1.81e-4)" "unprognostic (1.12e-1)" "potential prognostic unfavorable (4.43e-5)" "unprognostic (1.86e-2)" "unprognostic (1.09e-2)" "unprognostic (3.59e-1)" "unprognostic (5.35e-2)" "unprognostic (1.44e-1)" "unprognostic (7.12e-3)" "unprognostic (7.32e-2)" "unprognostic (8.19e-2)" "unprognostic (1.12e-1)" "unprognostic (1.96e-3)" "unprognostic (2.50e-3)" "unprognostic (1.41e-1)" "unprognostic (1.70e-1)" "unprognostic (4.14e-2)" "unprognostic (3.29e-2)" "unprognostic (1.97e-1)" ABRAXAS2 "ABRO1, Em:AC068896.4, FAM175B, KIAA0157" ENSG00000165660 "Abraxas 2, BRISC complex subunit" Q15018 10 124801819-124836667 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037591, HPA037592, HPA074089" Approved Supported "Primary cilium transition zone,Basal body,Cytosol" Yes No "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 52: Non-specific - Mitochondria" "Cluster 7: Non-specific - Transcription" 29 Cytosol "Primary cilium transition zone, Basal body" "HPA037591: , HPA037592: , HPA074089: " "unprognostic (1.92e-1)" "unprognostic (1.18e-1)" "unprognostic (5.49e-2)" "unprognostic (1.52e-1)" "unprognostic (3.59e-2)" "unprognostic (4.94e-1)" "potential prognostic favorable (4.69e-4)" "unprognostic (2.54e-1)" "unprognostic (2.74e-3)" "potential prognostic favorable (7.55e-7)" "unprognostic (1.61e-2)" "unprognostic (1.45e-1)" "unprognostic (2.75e-2)" "unprognostic (1.43e-1)" "unprognostic (5.23e-2)" "unprognostic (7.49e-2)" "unprognostic (4.46e-1)" "unprognostic (7.61e-2)" "unprognostic (1.22e-2)" "unprognostic (1.26e-2)" "unprognostic (2.95e-1)" "unprognostic (1.35e-3)" "unprognostic (1.54e-1)" "unprognostic (1.80e-1)" "unprognostic (2.39e-1)" "unprognostic (2.13e-1)" "unprognostic (1.72e-1)" "unprognostic (1.96e-1)" "unprognostic (3.57e-1)" ABT1 Esf2 ENSG00000146109 "Activator of basal transcription 1" Q9ULW3 6 26596953-26600739 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 109.6;Extravillous trophoblasts: 116.8;Late spermatids: 141.8;Migrating cytotrophoblasts: 116.6;Syncytiotrophoblasts: 116.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077039 Approved Vesicles NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 15: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 197 Vesicles "HPA077039: " "unprognostic (3.72e-2)" "unprognostic (7.67e-2)" "unprognostic (1.16e-2)" "unprognostic (2.86e-1)" "unprognostic (9.33e-2)" "unprognostic (1.57e-1)" "unprognostic (2.59e-1)" "unprognostic (1.03e-1)" "unprognostic (1.50e-1)" "unprognostic (1.98e-1)" "potential prognostic favorable (4.79e-4)" "unprognostic (2.72e-2)" "unprognostic (2.25e-2)" "unprognostic (4.12e-3)" "unprognostic (1.80e-3)" "unprognostic (5.27e-2)" "unprognostic (2.74e-1)" "unprognostic (2.21e-2)" "unprognostic (6.31e-3)" "unprognostic (1.29e-2)" "unprognostic (6.94e-2)" "unprognostic (9.80e-2)" "unprognostic (9.63e-2)" "unprognostic (1.60e-2)" "unprognostic (3.63e-2)" "unprognostic (9.47e-2)" "unprognostic (1.67e-2)" "unprognostic (2.45e-1)" "unprognostic (1.85e-1)" "unprognostic (1.50e-1)" "unprognostic (3.17e-2)" ABTB1 "BPOZ, Btb3, BTBD21, EF1ABP" ENSG00000114626 "Ankyrin repeat and BTB domain containing 1" Q969K4 3 127672935-127680926 "Predicted intracellular proteins" "Protein biosynthesis" "Elongation factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophil progenitors: 146.4;Neutrophils: 610.9;Platelets: 176.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "neutrophil: 825.0" "Lineage enriched" "Detected in all" 13 "granulocytes: 825.0" "Low cancer specificity" "Detected in all" "Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035022, HPA035023" Uncertain Supported Nucleoli,Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 17 Cytosol Nucleoli "HPA035022: , HPA035023: " "unprognostic (3.86e-3)" "unprognostic (1.91e-1)" "unprognostic (8.45e-2)" "unprognostic (2.35e-2)" "unprognostic (1.51e-1)" "unprognostic (2.70e-3)" "unprognostic (7.57e-3)" "unprognostic (4.25e-2)" "unprognostic (4.01e-1)" "unprognostic (1.36e-2)" "potential prognostic favorable (9.69e-4)" "unprognostic (4.32e-2)" "unprognostic (3.47e-1)" "unprognostic (3.15e-3)" "potential prognostic favorable (6.97e-4)" "unprognostic (3.54e-2)" "unprognostic (2.85e-1)" "unprognostic (1.24e-2)" "unprognostic (1.46e-1)" "unprognostic (1.61e-3)" "unprognostic (1.36e-1)" "unprognostic (5.17e-2)" "unprognostic (4.12e-2)" "unprognostic (2.44e-1)" "unprognostic (1.15e-1)" "unprognostic (1.39e-1)" "unprognostic (4.00e-3)" "unprognostic (1.99e-1)" "unprognostic (4.27e-2)" "unprognostic (1.95e-1)" "unprognostic (1.33e-2)" ABTB2 "ABTB2A, BTBD22, DKFZP586C1619" ENSG00000166016 "Ankyrin repeat and BTB domain containing 2" Q8N961 11 34150987-34358010 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.6" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 375.8;Endometrial glandular cells: 435.1;Renal collecting duct principal cells: 1082.9;Renal connecting tubule cells: 1049.1;Syncytiotrophoblasts: 504.1;Urothelial cells: 432.4" "Cell type enhanced" "Detected in all" "Bergmann glia: 243.0;committed oligodendrocyte precursor: 494.3;oligodendrocyte: 299.5" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 26.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "eosinophil: 5.0;plasmacytoid DC: 1.6" "Group enriched" "Detected in many" 14 "dendritic cells: 1.6;granulocytes: 5.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020065, HPA030699" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 51: Secretory epithelial cells - Mixed function" 5 Nucleoplasm Vesicles "HPA020065: , HPA030699: " "unprognostic (2.89e-2)" "unprognostic (1.09e-1)" "unprognostic (3.11e-1)" "unprognostic (1.90e-3)" "unprognostic (2.50e-1)" "unprognostic (1.51e-3)" "unprognostic (2.06e-1)" "unprognostic (4.19e-1)" "unprognostic (1.00e-1)" "unprognostic (1.31e-1)" "unprognostic (1.97e-2)" "unprognostic (1.53e-1)" "unprognostic (2.14e-1)" "unprognostic (1.67e-1)" "unprognostic (4.82e-2)" "unprognostic (2.11e-3)" "unprognostic (1.74e-3)" "unprognostic (1.72e-1)" "unprognostic (8.77e-2)" "unprognostic (3.67e-2)" "unprognostic (1.54e-1)" "unprognostic (4.15e-3)" "unprognostic (9.10e-2)" "unprognostic (3.54e-1)" "unprognostic (6.86e-2)" "unprognostic (8.49e-2)" "unprognostic (2.27e-1)" "unprognostic (1.12e-1)" "unprognostic (1.01e-1)" "unprognostic (8.47e-2)" "unprognostic (2.89e-1)" ABTB3 "ABTB2B, BTBD11, FLJ33957" ENSG00000151136 "Ankyrin repeat and BTB domain containing 3" A6QL63 12 107318421-107659642 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 28.3;parathyroid gland: 94.3" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 206.6;Choroid plexus epithelial cells: 211.5;Distal convoluted tubule cells: 311.9;Esophageal apical cells: 585.5;Esophageal basal cells: 310.0;Esophageal suprabasal cells: 670.6;Pituitary stem cells: 427.7;Suprabasal keratinocytes: 225.2;Thymocytes: 309.1;Thyrotrophs: 349.3" "Cell type enhanced" "Detected in all" "cerebellar inhibitory: 612.8;MGE interneuron: 457.8;midbrain-derived inhibitory: 811.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 3.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Skin - Keratinocyte (other), Testis - Peritubular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055898, HPA061334" Supported Nucleoplasm,Cytosol NA NA "Cluster 11: T-cells - Unknown function" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 9: T-cells - Adaptive immunity: Regulation" 1 Nucleoplasm Cytosol "HPA055898: , HPA061334: " "unprognostic (7.25e-2)" "unprognostic (5.65e-2)" "unprognostic (2.52e-1)" "unprognostic (5.90e-2)" "unprognostic (1.12e-1)" "unprognostic (2.93e-1)" "unprognostic (1.35e-2)" "unprognostic (5.76e-2)" "unprognostic (9.67e-3)" "unprognostic (7.15e-2)" "validated prognostic unfavorable (2.40e-6)" "validated prognostic unfavorable (1.80e-4)" "unprognostic (6.48e-2)" "unprognostic (4.29e-3)" "unprognostic (1.30e-1)" "unprognostic (6.05e-2)" "unprognostic (4.52e-2)" "unprognostic (4.27e-2)" "unprognostic (2.09e-1)" "unprognostic (4.05e-2)" "unprognostic (3.44e-3)" "unprognostic (2.21e-1)" "unprognostic (3.40e-2)" "unprognostic (8.62e-2)" "unprognostic (1.49e-1)" "unprognostic (2.13e-1)" "unprognostic (7.45e-2)" "unprognostic (4.83e-2)" "unprognostic (6.34e-2)" ACAA1 Lnc-Myd88 ENSG00000060971 "Acetyl-CoA acyltransferase 1" P09110 3 38103129-38137242 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "kidney: 198.3;liver: 616.3" "Cell type enhanced" "Detected in all" "Colonocytes: 311.3;Enterocytes: 407.7;Esophageal apical cells: 449.5;Hepatocytes: 841.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA006764, HPA007244" Enhanced Supported Peroxisomes NA NA 2300000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 12 Peroxisomes "HPA006764: , HPA007244: " "unprognostic (2.66e-2)" "unprognostic (9.87e-3)" "unprognostic (1.42e-1)" "unprognostic (6.18e-3)" "unprognostic (6.40e-2)" "unprognostic (6.86e-2)" "unprognostic (3.48e-1)" "unprognostic (1.33e-1)" "unprognostic (5.98e-3)" "potential prognostic unfavorable (6.26e-4)" "potential prognostic favorable (7.10e-11)" "unprognostic (1.47e-3)" "potential prognostic favorable (2.00e-5)" "unprognostic (5.74e-3)" "unprognostic (3.92e-3)" "unprognostic (8.21e-2)" "unprognostic (2.06e-1)" "unprognostic (7.24e-2)" "unprognostic (1.09e-1)" "unprognostic (1.49e-1)" "unprognostic (1.99e-1)" "unprognostic (5.85e-3)" "unprognostic (1.34e-1)" "unprognostic (2.90e-1)" "unprognostic (2.63e-1)" "unprognostic (1.40e-1)" "unprognostic (5.34e-2)" "unprognostic (2.08e-1)" "unprognostic (8.65e-2)" "unprognostic (1.98e-2)" "unprognostic (1.31e-2)" ACAA2 DSAEC ENSG00000167315 "Acetyl-CoA acyltransferase 2" P42765 18 49782164-49813953 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 945.6" "Cell type enhanced" "Detected in many" "Cholangiocytes: 248.6;Colonocytes: 297.7;Enteric transient amplifying cells: 170.3;Enterocytes: 199.2;Hepatocytes: 854.3;Late spermatids: 265.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Spleen - Macrophages, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042303 Approved Supported "Mitochondria,Basal body,Cytosol" NA NA 5100000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 36 Mitochondria "Basal body, Cytosol" "HPA042303: " "unprognostic (2.83e-1)" "unprognostic (1.82e-1)" "unprognostic (8.20e-2)" "unprognostic (4.08e-2)" "unprognostic (2.75e-2)" "unprognostic (5.45e-3)" "unprognostic (1.82e-2)" "potential prognostic unfavorable (7.91e-4)" "unprognostic (1.22e-1)" "unprognostic (2.94e-1)" "validated prognostic favorable (7.17e-11)" "validated prognostic favorable (1.98e-4)" "potential prognostic favorable (4.06e-5)" "unprognostic (3.29e-2)" "unprognostic (3.30e-2)" "unprognostic (7.73e-2)" "unprognostic (2.87e-1)" "unprognostic (9.18e-2)" "unprognostic (9.88e-2)" "unprognostic (1.15e-1)" "unprognostic (1.52e-1)" "unprognostic (9.03e-2)" "unprognostic (2.17e-1)" "unprognostic (1.41e-1)" "unprognostic (4.10e-2)" "unprognostic (1.67e-1)" "unprognostic (2.20e-1)" "unprognostic (1.73e-1)" "unprognostic (2.50e-1)" "unprognostic (2.39e-2)" "potential prognostic unfavorable (6.52e-4)" ACACA "ACAC, Acac1, ACACalpha, ACC, ACC-alpha, ACC1, ACCA, ACCalpha, hACC1" ENSG00000278540 "Acetyl-CoA carboxylase alpha" Q13085 17 37084992-37406836 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Allosteric enzyme, Ligase, Multifunctional enzyme" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 226.0;Bergmann glia: 168.0;Brain excitatory neurons: 278.5;Brain inhibitory neurons: 290.1;Choroid plexus epithelial cells: 420.0;Loop of henle epithelial cells: 179.5;Oligodendrocyte progenitor cells: 260.0;Oligodendrocytes: 259.6;Other brain neurons: 329.3;Papillary tip epithelial cells: 198.4;Renal collecting duct intercalated cells: 211.1;Renal collecting duct principal cells: 184.7;Renal connecting tubule cells: 155.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013715, HPA036650, HPA063018" Approved Supported "Nucleoli fibrillar center,Actin filaments,Cytosol" NA NA 310000 "Cluster 14: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 1: Neurons - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 109: Neurons - Neuronal signaling" 37 Cytosol "Nucleoli fibrillar center, Actin filaments" "CAB013715: , HPA036650: , HPA063018: " "unprognostic (1.11e-1)" "unprognostic (2.65e-2)" "unprognostic (2.18e-1)" "unprognostic (3.38e-3)" "unprognostic (6.14e-2)" "unprognostic (2.79e-3)" "unprognostic (1.90e-2)" "unprognostic (1.97e-1)" "unprognostic (4.06e-3)" "unprognostic (1.70e-2)" "unprognostic (1.52e-2)" "unprognostic (1.84e-1)" "potential prognostic unfavorable (9.72e-7)" "unprognostic (1.18e-3)" "unprognostic (2.66e-1)" "unprognostic (4.68e-2)" "unprognostic (3.10e-2)" "unprognostic (8.29e-2)" "unprognostic (3.58e-2)" "unprognostic (2.48e-1)" "unprognostic (2.85e-1)" "unprognostic (5.42e-2)" "unprognostic (3.99e-2)" "unprognostic (2.21e-1)" "unprognostic (4.11e-1)" "unprognostic (4.04e-1)" "unprognostic (2.88e-2)" "unprognostic (2.40e-2)" ACACB "ACACbeta, ACC-beta, ACC2, ACCB, ACCbeta, HACC275" ENSG00000076555 "Acetyl-CoA carboxylase beta" O00763 12 109116587-109268226 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Allosteric enzyme, Ligase, Multifunctional enzyme" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 171.9;skeletal muscle: 160.4" "Cell type enhanced" "Detected in many" "Adipocytes: 3715.9;Breast lactating cells: 983.0;Cardiomyocytes: 606.1;Distal convoluted tubule cells: 423.7;Myonuclei: 658.6" "Cell type enhanced" "Detected in all" "astrocyte: 297.7;Bergmann glia: 272.4;choroid plexus epithelial cell: 258.0" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 27.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 17.6" "Lineage enriched" "Detected in many" 6 "granulocytes: 17.6" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Minor Salivary Gland - Adipocytes (Minor salivary gland), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA006554 Enhanced "Intracellular and membrane" Enzyme NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 19: Astrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 89: Adipocytes - Lipid metabolism" 6 "HPA006554: " "unprognostic (5.93e-3)" "unprognostic (7.03e-2)" "unprognostic (3.98e-2)" "unprognostic (1.02e-1)" "unprognostic (1.52e-1)" "unprognostic (2.43e-1)" "unprognostic (2.96e-1)" "unprognostic (2.94e-3)" "unprognostic (6.47e-2)" "unprognostic (1.65e-2)" "validated prognostic favorable (2.51e-4)" "validated prognostic favorable (2.19e-5)" "potential prognostic favorable (5.48e-5)" "unprognostic (1.31e-2)" "unprognostic (7.19e-3)" "unprognostic (6.67e-2)" "unprognostic (1.18e-3)" "unprognostic (2.98e-1)" "unprognostic (9.41e-2)" "unprognostic (3.33e-2)" "unprognostic (8.14e-3)" "potential prognostic favorable (1.16e-4)" "unprognostic (7.21e-2)" "unprognostic (1.33e-2)" "unprognostic (4.53e-1)" "unprognostic (1.26e-1)" "unprognostic (2.13e-1)" "unprognostic (4.23e-1)" "unprognostic (3.04e-1)" "potential prognostic unfavorable (3.14e-4)" "unprognostic (9.14e-3)" ACAD10 MGC5601 ENSG00000111271 "Acyl-CoA dehydrogenase family member 10" Q6JQN1 12 111686053-111757107 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 81.7;Myonuclei: 101.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA067222 Uncertain NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 76: Non-specific - Metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 38: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 26 "HPA067222: " "unprognostic (4.27e-2)" "unprognostic (2.61e-3)" "unprognostic (4.23e-2)" "unprognostic (6.41e-2)" "unprognostic (3.40e-2)" "unprognostic (1.21e-1)" "unprognostic (1.07e-1)" "unprognostic (2.73e-1)" "unprognostic (2.14e-1)" "unprognostic (1.61e-1)" "unprognostic (2.84e-3)" "unprognostic (1.40e-1)" "unprognostic (2.32e-3)" "unprognostic (1.75e-1)" "unprognostic (1.14e-1)" "unprognostic (1.46e-1)" "unprognostic (1.38e-1)" "unprognostic (2.17e-1)" "unprognostic (6.45e-2)" "unprognostic (3.95e-3)" "unprognostic (7.80e-2)" "unprognostic (1.38e-2)" "unprognostic (3.24e-2)" "unprognostic (2.20e-2)" "unprognostic (1.21e-2)" "unprognostic (6.40e-3)" "unprognostic (4.06e-1)" "unprognostic (1.43e-1)" "unprognostic (7.64e-2)" "unprognostic (3.90e-2)" "unprognostic (3.53e-2)" ACAD11 FLJ12592 ENSG00000240303 "Acyl-CoA dehydrogenase family member 11" Q709F0 3 132558138-132660082 "Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "choroid plexus: 44.8;kidney: 60.1;liver: 96.9" "Cell type enhanced" "Detected in some" "Astrocytes: 78.5;Bergmann glia: 90.0;Brain excitatory neurons: 66.9;Brain inhibitory neurons: 84.8;Choroid plexus epithelial cells: 190.0;Ependymal cells: 122.7;Microglia: 45.3;Oligodendrocyte progenitor cells: 63.6;Oligodendrocytes: 80.2;Other brain neurons: 59.9" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 5 "Kidney Renal Clear Cell Carcinoma (TCGA): 92.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048317 Enhanced NA NA "Cluster 24: Non-specific - Transcription" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 36: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 22: Non-specific - Basic cellular functions" 34 "HPA048317: " "unprognostic (1.56e-1)" "unprognostic (6.15e-2)" "unprognostic (5.62e-3)" "unprognostic (9.20e-2)" "unprognostic (1.46e-1)" "unprognostic (3.14e-2)" "unprognostic (1.40e-1)" "unprognostic (4.87e-2)" "unprognostic (6.49e-3)" "unprognostic (4.66e-3)" "potential prognostic favorable (2.52e-8)" "unprognostic (1.60e-3)" "unprognostic (1.05e-1)" "unprognostic (5.76e-3)" "unprognostic (7.40e-2)" "unprognostic (6.28e-2)" "unprognostic (1.53e-3)" "unprognostic (3.79e-1)" "unprognostic (1.33e-1)" "unprognostic (7.28e-2)" "unprognostic (1.19e-1)" "unprognostic (1.11e-1)" "unprognostic (6.99e-3)" "unprognostic (7.69e-2)" "unprognostic (2.54e-2)" "unprognostic (1.47e-2)" "unprognostic (2.30e-1)" "unprognostic (6.64e-2)" "unprognostic (2.58e-1)" "unprognostic (1.88e-1)" "unprognostic (3.39e-2)" ACAD8 ENSG00000151498 "Acyl-CoA dehydrogenase family member 8" Q9UKU7 11 134253548-134265855 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Branched-chain amino acid catabolism, Transcription, Transcription regulation" "Activator, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophil progenitors: 58.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040689, HPA043903" Enhanced NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 24: Non-specific - Unknown function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 3 "HPA040689: , HPA043903: " "unprognostic (2.87e-1)" "potential prognostic unfavorable (7.51e-4)" "unprognostic (2.25e-2)" "unprognostic (3.47e-1)" "unprognostic (2.53e-2)" "unprognostic (1.91e-2)" "unprognostic (7.63e-3)" "potential prognostic favorable (2.99e-4)" "unprognostic (9.44e-2)" "unprognostic (8.29e-2)" "potential prognostic favorable (3.02e-11)" "unprognostic (2.21e-2)" "potential prognostic favorable (6.66e-7)" "unprognostic (2.21e-1)" "unprognostic (1.20e-2)" "unprognostic (5.46e-2)" "unprognostic (1.22e-1)" "unprognostic (2.05e-2)" "unprognostic (1.27e-1)" "unprognostic (1.83e-1)" "unprognostic (6.38e-3)" "unprognostic (1.79e-1)" "unprognostic (6.92e-2)" "unprognostic (2.27e-1)" "unprognostic (3.32e-2)" "unprognostic (2.38e-1)" "unprognostic (3.26e-1)" "unprognostic (1.37e-1)" "unprognostic (5.36e-2)" "unprognostic (4.72e-2)" "unprognostic (1.08e-2)" ACAD9 "MGC14452, NPD002" ENSG00000177646 "Acyl-CoA dehydrogenase family member 9" Q9H845 3 128879596-128924003 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skin - Keratinocyte (other), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037716, HPA046720" Supported Enhanced Mitochondria No No 8900 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 24: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 63: Non-specific - Protein processing" "Cluster 51: Secretory epithelial cells - Mixed function" 60 Mitochondria "HPA037716: , HPA046720: " "unprognostic (1.07e-1)" "unprognostic (4.12e-2)" "unprognostic (2.16e-1)" "unprognostic (3.37e-1)" "unprognostic (3.85e-3)" "unprognostic (8.34e-2)" "unprognostic (5.75e-2)" "unprognostic (4.34e-2)" "unprognostic (2.36e-1)" "unprognostic (9.18e-2)" "potential prognostic favorable (8.34e-7)" "unprognostic (7.70e-2)" "unprognostic (1.65e-2)" "unprognostic (4.65e-3)" "unprognostic (1.88e-2)" "unprognostic (1.25e-2)" "unprognostic (2.76e-1)" "unprognostic (4.51e-1)" "unprognostic (1.38e-1)" "unprognostic (5.58e-2)" "unprognostic (3.39e-1)" "unprognostic (4.91e-3)" "unprognostic (3.05e-3)" "unprognostic (1.22e-1)" "unprognostic (1.98e-1)" "unprognostic (4.60e-2)" "unprognostic (4.90e-2)" "unprognostic (1.76e-2)" "unprognostic (2.00e-1)" "unprognostic (3.17e-1)" "unprognostic (1.20e-1)" ACADL "ACAD4, LCAD" ENSG00000115361 "Acyl-CoA dehydrogenase long chain" P28330 2 210187126-210225447 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 24.9;liver: 26.3" "Cell type enhanced" "Detected in many" "Adipocytes: 140.1;Alveolar cells type 1: 97.3;Alveolar cells type 2: 126.8;Early spermatids: 94.2;Late spermatids: 105.6;Leydig cells: 164.1;Medullary thymic epithelial cells: 86.4;Peritubular myoid cells: 162.3;Pituicytes/FSCs: 87.8;Prostatic glandular cells: 318.0;Proximal tubule cells: 82.7;Renal collecting duct intercalated cells: 94.7;Renal collecting duct principal cells: 96.9;Thymic myoid cells: 165.9" "Cell type enriched" "Detected in many" 4 "fibroblast: 149.5" "Cancer enhanced" "Detected in some" "Kidney Chromophobe (TCGA): 17.8;Kidney Renal Clear Cell Carcinoma (TCGA): 17.2" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 2.8;Rhabdoid: 2.4;testis cancer: 2.2" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011990 Enhanced Supported NA NA "Cluster 70: Non-specific - Protein processing" "Cluster 39: Astrocytes - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 4 "HPA011990: " "unprognostic (9.92e-3)" "unprognostic (2.32e-2)" "unprognostic (1.55e-1)" "validated prognostic favorable (6.02e-9)" "validated prognostic favorable (5.52e-4)" "unprognostic (1.27e-2)" "unprognostic (1.46e-3)" "potential prognostic favorable (3.95e-6)" "unprognostic (2.95e-1)" "unprognostic (6.48e-2)" "unprognostic (2.36e-3)" "unprognostic (1.77e-1)" "unprognostic (9.04e-2)" ACADM "ACAD1, MCAD, MCADH" ENSG00000117054 "Acyl-CoA dehydrogenase medium chain" P11310 1 75724431-75787575 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 343.6;skeletal muscle: 357.2;tongue: 445.9" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 740.0;Hepatocytes: 338.0;Parietal cells: 316.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Skin - Sebaceous gland cells, Stomach - Parietal cells, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006198, HPA026542" Enhanced Supported "Mitochondria,Perinuclear theca,Calyx,Principal piece" NA NA 480000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 76: Non-specific - Metabolism" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 84: Apical squamous epithelium - Cornification" 12 Mitochondria "Perinuclear theca, Calyx, Principal piece" "HPA006198: , HPA026542: " "unprognostic (6.45e-2)" "unprognostic (6.04e-2)" "unprognostic (2.18e-1)" "unprognostic (1.44e-1)" "unprognostic (7.57e-3)" "unprognostic (2.73e-3)" "unprognostic (8.00e-2)" "unprognostic (2.55e-1)" "unprognostic (2.07e-2)" "unprognostic (2.75e-2)" "validated prognostic favorable (4.28e-13)" "validated prognostic favorable (1.48e-4)" "unprognostic (1.19e-2)" "unprognostic (7.83e-2)" "unprognostic (2.51e-2)" "unprognostic (1.10e-1)" "unprognostic (3.13e-2)" "unprognostic (7.77e-2)" "unprognostic (1.14e-1)" "unprognostic (3.22e-2)" "unprognostic (7.49e-2)" "unprognostic (2.40e-1)" "unprognostic (1.35e-2)" "unprognostic (2.68e-1)" "unprognostic (7.10e-3)" "unprognostic (1.03e-1)" "unprognostic (1.13e-1)" "unprognostic (1.10e-1)" "unprognostic (4.55e-2)" "unprognostic (1.80e-1)" "unprognostic (2.72e-2)" ACADS "ACAD3, SCAD" ENSG00000122971 "Acyl-CoA dehydrogenase short chain" P16219 12 120725774-120740008 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 253.5;skeletal muscle: 160.6" "Cell type enhanced" "Detected in many" "Colonocytes: 276.5;Cytotrophoblasts: 100.9;Enteric stem cells: 141.8;Enteric transient amplifying cells: 204.0;Enterocytes: 385.9;Hepatocytes: 241.3;Paneth cells: 112.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 135.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004799, CAB019284, HPA022271" Enhanced Supported "Nucleoplasm,Centrosome,Mitochondria,Mid piece,Principal piece,End piece" NA NA 14000 "Cluster 13: Non-specific - Mitochondria" "Cluster 77: Intestine - Digestion" "Cluster 19: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 1 Mitochondria "Nucleoplasm, Centrosome, Mid piece, Principal piece, End piece" "CAB019284: , HPA004799: , HPA022271: " "unprognostic (3.88e-1)" "unprognostic (1.25e-1)" "unprognostic (1.17e-1)" "unprognostic (1.09e-2)" "unprognostic (1.28e-2)" "unprognostic (2.31e-1)" "validated prognostic unfavorable (1.52e-4)" "validated prognostic unfavorable (5.91e-5)" "unprognostic (1.18e-2)" "unprognostic (2.61e-1)" "potential prognostic favorable (5.62e-5)" "unprognostic (4.05e-2)" "potential prognostic favorable (1.44e-4)" "potential prognostic favorable (6.09e-4)" "unprognostic (1.31e-1)" "unprognostic (5.03e-3)" "unprognostic (7.39e-2)" "unprognostic (7.12e-2)" "unprognostic (1.73e-1)" "unprognostic (7.49e-2)" "unprognostic (3.05e-1)" "unprognostic (1.17e-1)" "unprognostic (1.24e-3)" "unprognostic (4.68e-1)" "unprognostic (4.56e-2)" "unprognostic (3.42e-2)" "unprognostic (6.56e-2)" "unprognostic (4.18e-3)" "unprognostic (1.61e-1)" "unprognostic (6.54e-2)" "potential prognostic favorable (4.58e-5)" ACADSB "ACAD7, SBCAD" ENSG00000196177 "Acyl-CoA dehydrogenase short/branched chain" P45954 10 123008979-123058290 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 336.7" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 655.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "breast cancer: 44.3" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Alveolar cells type 2, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041458, HPA063555" Enhanced Supported Mitochondria NA NA 50000 "Cluster 39: T-cells - T-cell receptor" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 16: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 6 Mitochondria "HPA041458: , HPA063555: " "unprognostic (9.00e-2)" "unprognostic (5.74e-2)" "unprognostic (4.01e-2)" "unprognostic (6.07e-2)" "potential prognostic favorable (5.02e-4)" "unprognostic (1.23e-2)" "unprognostic (2.14e-1)" "unprognostic (5.44e-2)" "unprognostic (2.93e-2)" "unprognostic (1.04e-1)" "validated prognostic favorable (4.41e-11)" "validated prognostic favorable (9.15e-5)" "unprognostic (3.96e-2)" "unprognostic (3.85e-2)" "unprognostic (5.06e-2)" "unprognostic (2.34e-3)" "unprognostic (8.67e-2)" "unprognostic (1.33e-1)" "unprognostic (4.84e-2)" "unprognostic (1.64e-1)" "potential prognostic unfavorable (9.66e-5)" "unprognostic (2.75e-2)" "unprognostic (3.12e-2)" "unprognostic (7.86e-2)" "unprognostic (1.12e-2)" "unprognostic (2.29e-1)" "unprognostic (1.15e-1)" "unprognostic (2.06e-1)" "unprognostic (1.25e-1)" "unprognostic (4.52e-3)" "unprognostic (1.20e-1)" ACADVL "ACAD6, LCACD, VLCAD" ENSG00000072778 "Acyl-CoA dehydrogenase very long chain" P49748 17 7217125-7225266 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 798.8;Cytotrophoblasts: 557.4;Esophageal apical cells: 784.3;Syncytiotrophoblasts: 828.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019006, HPA020595" Enhanced Supported Nucleoplasm,Nucleoli,Mitochondria NA NA 69000 "Cluster 25: Non-specific - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 42: Non-specific - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 10 Mitochondria "Nucleoplasm, Nucleoli" "HPA019006: , HPA020595: " "unprognostic (8.19e-2)" "unprognostic (1.63e-1)" "unprognostic (7.29e-2)" "unprognostic (1.87e-1)" "unprognostic (1.73e-1)" "unprognostic (1.91e-2)" "unprognostic (1.29e-2)" "unprognostic (1.27e-2)" "unprognostic (1.56e-1)" "unprognostic (3.28e-1)" "potential prognostic favorable (7.42e-8)" "unprognostic (1.67e-2)" "unprognostic (9.27e-3)" "unprognostic (4.77e-3)" "potential prognostic favorable (6.89e-4)" "unprognostic (1.01e-1)" "unprognostic (8.89e-3)" "unprognostic (2.44e-1)" "unprognostic (1.83e-1)" "unprognostic (1.60e-1)" "unprognostic (4.16e-2)" "unprognostic (4.09e-2)" "unprognostic (1.85e-3)" "unprognostic (1.32e-1)" "unprognostic (1.48e-1)" "unprognostic (6.82e-2)" "unprognostic (2.14e-1)" "unprognostic (1.68e-2)" "unprognostic (1.43e-1)" "unprognostic (6.88e-2)" "unprognostic (1.71e-1)" ACAN "AGC1, CSPG1, CSPGCP, MSK16" ENSG00000157766 Aggrecan P16112 15 88803436-88875353 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "blood vessel: 35.7" "Cell type enriched" "Detected in some" 9 "Extravillous trophoblasts: 224.7" "Cell type enriched" "Detected in some" 4 "committed oligodendrocyte precursor: 70.7" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 13.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bone cancer: 7.5;skin cancer: 8.0" "Adipose visceral - Smooth muscle cells, Adrenal gland - Smooth muscle cells, Heart muscle - Smooth muscle cells, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB016377, HPA038241, HPA038242" Enhanced "Secreted to extracellular matrix" "No annotated function" NA NA 48000000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 1: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 1 "CAB016377: , HPA038241: , HPA038242: " "unprognostic (2.39e-1)" "unprognostic (6.50e-3)" "unprognostic (8.70e-2)" "unprognostic (2.96e-2)" "unprognostic (1.75e-1)" "unprognostic (1.16e-1)" "unprognostic (5.22e-3)" "unprognostic (1.17e-1)" "unprognostic (1.98e-1)" "unprognostic (5.92e-2)" "unprognostic (1.66e-1)" "unprognostic (1.01e-3)" "potential prognostic unfavorable (9.30e-8)" "unprognostic (6.89e-3)" "unprognostic (3.24e-2)" "unprognostic (2.58e-1)" "unprognostic (5.31e-1)" "unprognostic (2.05e-1)" "unprognostic (7.26e-2)" "unprognostic (1.41e-1)" "unprognostic (4.44e-3)" "unprognostic (4.06e-2)" "unprognostic (6.16e-2)" "unprognostic (4.47e-2)" "unprognostic (2.98e-2)" ACAP1 "CENTB1, KIAA0050" ENSG00000072818 "ArfGAP with coiled-coil, ankyrin repeat and PH domains 1" Q15027 17 7336529-7351477 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "GTPase activation" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 38.8;intestine: 40.5;lymphoid tissue: 93.2" "Cell type enriched" "Detected in many" 11 "Late spermatids: 4047.4" "Cell type enriched" "Detected in many" 6 "leukocyte: 131.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 58 "Leukemia: 31.2;lymphoma: 33.3;Myeloma: 17.4" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Minor Salivary Gland - T-cells, Prostate - T-cells, Skin - T-cells, Stomach - T-cells, Testis - Late spermatids, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA075570 Approved Uncertain "Golgi apparatus" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 11 "Golgi apparatus" "HPA075570: " "unprognostic (7.78e-2)" "unprognostic (2.15e-3)" "unprognostic (9.61e-3)" "potential prognostic favorable (7.24e-4)" "unprognostic (2.55e-1)" "unprognostic (4.39e-1)" "potential prognostic favorable (1.02e-4)" "unprognostic (2.36e-3)" "unprognostic (1.23e-1)" "unprognostic (4.43e-2)" "unprognostic (2.19e-3)" "unprognostic (6.95e-3)" "potential prognostic favorable (9.58e-4)" "unprognostic (2.01e-1)" "unprognostic (4.27e-1)" "unprognostic (1.26e-1)" "unprognostic (1.62e-2)" "unprognostic (7.29e-2)" "potential prognostic unfavorable (7.71e-4)" "unprognostic (6.84e-2)" "unprognostic (1.02e-1)" "unprognostic (2.81e-2)" "unprognostic (1.53e-3)" "unprognostic (8.69e-2)" "unprognostic (5.04e-2)" "unprognostic (1.24e-1)" "unprognostic (1.24e-1)" ACAP2 "CENTB2, CNT-B2, KIAA0041" ENSG00000114331 "ArfGAP with coiled-coil, ankyrin repeat and PH domains 2" Q15057 3 195274745-195443044 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 1126.0;Neutrophils: 2226.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 227.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034807, HPA034808" Supported Approved Endosomes NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 24: Neutrophils - Innate immunity signal integration" 7 Endosomes "HPA034807: , HPA034808: " "unprognostic (4.95e-1)" "unprognostic (4.40e-2)" "unprognostic (1.77e-1)" "unprognostic (7.16e-2)" "unprognostic (2.60e-1)" "unprognostic (6.91e-2)" "unprognostic (3.57e-1)" "unprognostic (1.59e-1)" "unprognostic (6.44e-2)" "potential prognostic unfavorable (7.68e-4)" "potential prognostic favorable (1.60e-4)" "unprognostic (6.29e-3)" "unprognostic (2.88e-2)" "unprognostic (2.36e-3)" "unprognostic (8.87e-2)" "potential prognostic unfavorable (9.34e-4)" "unprognostic (1.27e-1)" "unprognostic (6.22e-3)" "unprognostic (3.76e-2)" "unprognostic (9.21e-3)" "unprognostic (4.85e-3)" "unprognostic (8.22e-2)" "unprognostic (4.21e-3)" "unprognostic (9.16e-2)" "unprognostic (1.24e-1)" "unprognostic (3.63e-2)" "unprognostic (5.17e-2)" "unprognostic (2.99e-1)" "unprognostic (2.33e-1)" "unprognostic (6.08e-2)" "unprognostic (1.58e-1)" ACAP3 "CENTB5, KIAA1716" ENSG00000131584 "ArfGAP with coiled-coil, ankyrin repeat and PH domains 3" Q96P50 1 1292390-1309609 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 155.0" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 91.3;Oligodendrocyte progenitor cells: 143.9;Retinal bipolar cells: 101.7;Rod photoreceptor cells: 111.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049317, HPA058381" Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 35: Neurons - Synaptic function & neurogenesis" 5 Nucleoplasm "Golgi apparatus" "HPA049317: , HPA058381: " "unprognostic (7.42e-2)" "unprognostic (1.26e-2)" "unprognostic (6.25e-2)" "unprognostic (3.75e-1)" "unprognostic (2.60e-1)" "unprognostic (4.18e-2)" "unprognostic (2.64e-1)" "potential prognostic favorable (9.60e-4)" "unprognostic (3.71e-3)" "unprognostic (2.80e-1)" "unprognostic (1.65e-1)" "unprognostic (2.24e-1)" "potential prognostic favorable (4.82e-6)" "potential prognostic unfavorable (9.83e-4)" "unprognostic (1.01e-1)" "unprognostic (2.96e-2)" "unprognostic (1.01e-1)" "unprognostic (5.63e-2)" "unprognostic (2.13e-1)" "unprognostic (1.22e-1)" "unprognostic (3.89e-2)" "unprognostic (5.57e-3)" "potential prognostic unfavorable (7.92e-4)" "unprognostic (7.28e-2)" "unprognostic (1.41e-2)" "unprognostic (6.39e-3)" "unprognostic (2.24e-1)" "unprognostic (1.44e-2)" "unprognostic (2.01e-1)" "potential prognostic unfavorable (9.93e-4)" "unprognostic (6.95e-2)" ACAT1 "ACAT, THIL" ENSG00000075239 "Acetyl-CoA acetyltransferase 1" P24752 11 108116695-108147603 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 580.7;liver: 905.7" "Cell type enhanced" "Detected in many" "Early spermatids: 444.2;Hepatocytes: 804.5;Late primary spermatocytes: 403.6;Parietal cells: 484.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 542.4" "Region enriched" "Detected in all" 4 "choroid plexus: 124.0" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Stomach - Parietal cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004428, HPA007569" Enhanced Enhanced Mitochondria NA NA 730000 "Cluster 33: Non-specific - ATP binding" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 24: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 15 Mitochondria "HPA004428: , HPA007569: " "unprognostic (9.86e-2)" "unprognostic (2.31e-2)" "unprognostic (3.32e-1)" "unprognostic (1.01e-1)" "unprognostic (8.32e-2)" "unprognostic (2.05e-2)" "unprognostic (4.08e-1)" "unprognostic (3.01e-2)" "unprognostic (4.54e-2)" "unprognostic (1.29e-1)" "potential prognostic favorable (1.55e-11)" "unprognostic (9.23e-3)" "potential prognostic favorable (3.02e-5)" "potential prognostic favorable (4.27e-4)" "unprognostic (1.04e-3)" "unprognostic (5.77e-3)" "unprognostic (3.21e-1)" "unprognostic (1.73e-1)" "unprognostic (2.84e-1)" "unprognostic (1.60e-2)" "unprognostic (1.17e-1)" "unprognostic (3.18e-2)" "unprognostic (3.99e-2)" "unprognostic (4.19e-2)" "unprognostic (2.91e-2)" "unprognostic (2.04e-1)" "unprognostic (1.62e-2)" "unprognostic (1.67e-1)" "unprognostic (2.78e-1)" "unprognostic (4.64e-2)" "unprognostic (6.88e-2)" ACAT2 ENSG00000120437 "Acetyl-CoA acetyltransferase 2" Q9BWD1 6 159762045-159779112 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 216.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 213.9;Breast lactating cells: 235.5;Early spermatids: 247.6;Esophageal apical cells: 197.6;Esophageal basal cells: 184.4;Esophageal suprabasal cells: 223.5;Late spermatids: 190.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB021106, HPA025736, HPA025765, HPA025811" Enhanced Approved Nucleoplasm,Cytosol NA NA 2500000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 49: Hindbrain - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 3 Cytosol Nucleoplasm "CAB021106: , HPA025736: , HPA025765: , HPA025811: " "unprognostic (5.58e-2)" "unprognostic (1.77e-1)" "potential prognostic unfavorable (2.34e-5)" "unprognostic (1.95e-2)" "unprognostic (1.50e-2)" "unprognostic (1.54e-1)" "unprognostic (7.76e-2)" "unprognostic (1.59e-1)" "unprognostic (3.50e-1)" "potential prognostic unfavorable (8.27e-4)" "unprognostic (3.83e-2)" "unprognostic (9.94e-2)" "unprognostic (9.83e-2)" "unprognostic (1.06e-1)" "unprognostic (3.24e-3)" "unprognostic (2.28e-3)" "unprognostic (1.31e-1)" "unprognostic (6.50e-2)" "unprognostic (3.35e-3)" "unprognostic (1.77e-1)" "unprognostic (3.07e-1)" "unprognostic (6.19e-2)" "unprognostic (5.95e-2)" "unprognostic (2.47e-1)" "unprognostic (9.42e-2)" "unprognostic (1.38e-1)" "unprognostic (8.72e-2)" "unprognostic (2.20e-1)" "unprognostic (4.77e-2)" "unprognostic (4.69e-3)" "unprognostic (4.39e-2)" ACBD3 "GCP60, GOCAP1, GOLPH1, PAP7" ENSG00000182827 "Acyl-CoA binding domain containing 3" Q9H3P7 1 226144679-226186741 "Plasma proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015594 Approved Supported "Golgi apparatus" NA NA 12000 "Cluster 20: Non-specific - DNA binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 45: Non-specific - Nuclear processes" "Cluster 8: Non-specific - Secretory pathway" 23 "Golgi apparatus" "HPA015594: " "unprognostic (4.20e-2)" "unprognostic (3.27e-3)" "unprognostic (1.48e-1)" "unprognostic (4.49e-3)" "unprognostic (1.11e-1)" "unprognostic (1.94e-3)" "unprognostic (3.28e-1)" "unprognostic (5.89e-2)" "unprognostic (2.02e-1)" "unprognostic (1.99e-3)" "potential prognostic favorable (7.39e-5)" "unprognostic (4.58e-1)" "unprognostic (1.33e-2)" "unprognostic (3.34e-2)" "unprognostic (2.81e-3)" "unprognostic (1.12e-1)" "potential prognostic unfavorable (7.01e-4)" "unprognostic (1.69e-1)" "unprognostic (3.11e-1)" "unprognostic (2.45e-1)" "unprognostic (2.43e-3)" "unprognostic (5.34e-3)" "unprognostic (1.22e-2)" "unprognostic (9.72e-2)" "unprognostic (1.43e-1)" "unprognostic (4.37e-3)" "unprognostic (1.67e-1)" "unprognostic (6.15e-2)" "unprognostic (3.35e-1)" "unprognostic (3.76e-3)" "unprognostic (2.04e-1)" ACBD4 FLJ13322 ENSG00000181513 "Acyl-CoA binding domain containing 4" Q8NC06 17 45132600-45144181 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 90.7" "Cell type enhanced" "Detected in many" "Enterocytes: 62.3;Proximal tubule cells: 39.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051772 Approved Approved Nucleoplasm,Vesicles Yes No "Cluster 24: Non-specific - Transcription" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 1: Enterocytes - Absorption and Digestion" 7 "Nucleoplasm, Vesicles" "HPA051772: " "unprognostic (1.16e-1)" "unprognostic (1.46e-1)" "unprognostic (5.37e-1)" "unprognostic (1.76e-1)" "unprognostic (3.66e-2)" "unprognostic (3.88e-2)" "unprognostic (1.21e-3)" "unprognostic (2.85e-1)" "unprognostic (5.05e-2)" "unprognostic (6.60e-2)" "potential prognostic favorable (2.59e-6)" "unprognostic (3.35e-3)" "potential prognostic favorable (3.97e-4)" "unprognostic (2.00e-3)" "unprognostic (2.67e-3)" "unprognostic (6.95e-2)" "unprognostic (7.12e-2)" "unprognostic (2.81e-2)" "unprognostic (1.45e-1)" "unprognostic (2.11e-2)" "unprognostic (7.58e-3)" "unprognostic (5.10e-3)" "unprognostic (3.26e-2)" "unprognostic (3.29e-1)" "unprognostic (2.97e-2)" "unprognostic (3.61e-1)" "unprognostic (4.21e-1)" "unprognostic (2.09e-1)" "unprognostic (1.44e-1)" "unprognostic (1.97e-1)" "unprognostic (3.42e-2)" ACBD5 "DKFZp434A2417, KIAA1996" ENSG00000107897 "Acyl-CoA binding domain containing 5" Q5T8D3 10 27168135-27243046 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Autophagy, Transport" Leukodystrophy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epicardial cells: 175.1;Retinal pigment epithelial cells: 187.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011861, HPA012145" Enhanced Enhanced Peroxisomes NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 9: T-cells - Adaptive immunity: Regulation" 16 Peroxisomes "HPA011861: , HPA012145: " "unprognostic (2.64e-2)" "unprognostic (2.39e-3)" "unprognostic (3.23e-1)" "unprognostic (3.13e-2)" "unprognostic (1.19e-1)" "unprognostic (1.92e-2)" "unprognostic (8.80e-2)" "unprognostic (2.30e-3)" "unprognostic (2.35e-2)" "unprognostic (8.43e-3)" "potential prognostic favorable (2.54e-7)" "unprognostic (2.08e-2)" "unprognostic (3.21e-1)" "unprognostic (1.86e-1)" "unprognostic (1.68e-3)" "unprognostic (1.37e-1)" "unprognostic (6.49e-2)" "unprognostic (5.18e-3)" "unprognostic (1.67e-1)" "unprognostic (1.16e-1)" "unprognostic (4.05e-3)" "unprognostic (9.14e-2)" "unprognostic (1.46e-1)" "unprognostic (6.00e-2)" "unprognostic (1.14e-1)" "unprognostic (1.56e-1)" "unprognostic (1.63e-1)" "unprognostic (1.20e-2)" "unprognostic (1.40e-1)" "unprognostic (3.46e-2)" "unprognostic (1.47e-1)" ACBD6 MGC2404 ENSG00000230124 "Acyl-CoA binding domain containing 6" Q9BR61 1 180269653-180502954 "Predicted intracellular proteins" "Autism spectrum disorder, Disease variant, Dystonia, Intellectual disability, Parkinsonism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028179, HPA028457" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 39: Testis - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 24: Neutrophils - Innate immunity signal integration" 7 Nucleoplasm Cytosol "HPA028179: , HPA028457: " "unprognostic (3.70e-2)" "unprognostic (1.34e-2)" "unprognostic (3.36e-2)" "unprognostic (1.88e-1)" "unprognostic (1.64e-1)" "unprognostic (1.83e-1)" "unprognostic (8.75e-2)" "unprognostic (1.33e-2)" "unprognostic (5.57e-2)" "unprognostic (1.46e-2)" "unprognostic (2.33e-3)" "unprognostic (9.05e-2)" "unprognostic (1.39e-1)" "unprognostic (1.73e-2)" "unprognostic (1.04e-3)" "unprognostic (2.33e-2)" "unprognostic (1.05e-1)" "unprognostic (6.33e-2)" "unprognostic (1.08e-1)" "unprognostic (1.96e-2)" "unprognostic (2.91e-2)" "unprognostic (8.87e-2)" "unprognostic (6.02e-3)" "unprognostic (7.56e-2)" "unprognostic (1.66e-1)" "unprognostic (1.34e-2)" "unprognostic (1.07e-1)" "unprognostic (1.00e-1)" "unprognostic (2.65e-1)" "unprognostic (1.51e-2)" "unprognostic (1.42e-1)" ACBD7 "bA455B2.2, FLJ38219" ENSG00000176244 "Acyl-CoA binding domain containing 7" Q8N6N7 10 15075475-15088776 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "brain: 69.8" "Cell type enhanced" "Detected in many" "Astrocytes: 33.0;Bergmann glia: 34.7;Endometrial ciliated cells: 12.1;Ependymal cells: 16.1;Epididymal efferent duct ciliated cells: 10.5;Fallopian tube ciliated cells: 15.0;Late primary spermatocytes: 15.6;Respiratory ciliated cells: 12.9" "Cell type enhanced" "Detected in many" "astrocyte: 31.9;Bergmann glia: 40.3;ependymal cell: 21.2" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 15.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Region enriched" "Detected in all" 5 "olfactory bulb: 17.6" "Low region specificity" "Detected in all" "HPA043326, HPA062478" Approved Vesicles,Cytosol NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 59: Leukemia - T-cell receptor" "Cluster 28: Astrocytes - Homeostasis & neuron support" 2 "Vesicles, Cytosol" "HPA043326: , HPA062478: " "unprognostic (3.61e-3)" "unprognostic (5.67e-2)" "unprognostic (1.41e-1)" "unprognostic (4.50e-2)" "unprognostic (9.63e-3)" "unprognostic (3.31e-2)" "unprognostic (9.81e-2)" "unprognostic (4.40e-3)" "unprognostic (2.90e-2)" "unprognostic (3.07e-2)" "unprognostic (3.96e-2)" "unprognostic (1.38e-1)" "unprognostic (4.32e-2)" "unprognostic (6.11e-2)" "unprognostic (5.74e-2)" "unprognostic (1.31e-1)" "unprognostic (3.61e-2)" "unprognostic (3.18e-2)" "unprognostic (3.64e-1)" "unprognostic (2.50e-1)" "unprognostic (3.45e-3)" "unprognostic (2.16e-1)" "unprognostic (1.61e-1)" "unprognostic (2.81e-1)" "unprognostic (1.22e-1)" ACCS "ACS, PHACS" ENSG00000110455 "1-aminocyclopropane-1-carboxylate synthase homolog (inactive)" Q96QU6 11 44065925-44084237 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Platelets: 46.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018873, HPA021654" Approved Approved "Golgi apparatus" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 36: Choroid plexus - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 7: Non-specific - Transcription" 1 "Golgi apparatus" "HPA018873: , HPA021654: " "unprognostic (1.48e-1)" "unprognostic (3.45e-2)" "unprognostic (4.67e-2)" "unprognostic (1.52e-1)" "unprognostic (2.74e-3)" "unprognostic (9.61e-2)" "potential prognostic unfavorable (1.62e-4)" "unprognostic (1.95e-1)" "unprognostic (5.13e-2)" "unprognostic (4.56e-3)" "unprognostic (1.31e-2)" "unprognostic (1.36e-2)" "potential prognostic favorable (6.51e-10)" "unprognostic (3.72e-1)" "unprognostic (6.79e-3)" "potential prognostic favorable (6.48e-4)" "unprognostic (2.12e-1)" "unprognostic (1.40e-2)" "unprognostic (1.06e-1)" "unprognostic (2.03e-1)" "unprognostic (6.70e-2)" "unprognostic (2.69e-3)" "unprognostic (1.69e-3)" "unprognostic (3.41e-2)" "unprognostic (1.30e-2)" "unprognostic (6.17e-2)" "unprognostic (1.56e-1)" "unprognostic (1.86e-1)" "unprognostic (1.74e-1)" "unprognostic (2.19e-2)" "unprognostic (6.53e-2)" ACCSL ENSG00000205126 "1-aminocyclopropane-1-carboxylate synthase homolog (inactive) like" Q4AC99 11 44047981-44059977 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Melanocytes: 10.3;Platelets: 5.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA065042 Approved Cytosol NA NA "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 61: Schwann cells & Melanocytes - Mixed function" Cytosol "HPA065042: " ACD "Pip1, Ptop, Tint1, Tpp1" ENSG00000102977 "ACD shelterin complex subunit and telomerase recruitment factor" Q96AP0 16 67657512-67660810 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" DNA-binding "Disease variant, Dyskeratosis congenita" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 54.6;Early spermatids: 47.7;Late primary spermatocytes: 56.2;Late spermatids: 89.9;Oocytes: 78.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049411, HPA057660" Approved Enhanced "Nuclear bodies" NA Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 64: Non-specific - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 41 "Nuclear bodies" "HPA049411: , HPA057660: " "unprognostic (1.60e-1)" "unprognostic (2.22e-2)" "unprognostic (2.34e-1)" "unprognostic (1.75e-1)" "unprognostic (2.77e-2)" "unprognostic (2.51e-1)" "unprognostic (3.67e-2)" "unprognostic (1.48e-2)" "unprognostic (8.04e-3)" "unprognostic (1.34e-1)" "unprognostic (6.35e-3)" "unprognostic (1.09e-1)" "unprognostic (1.78e-2)" "potential prognostic unfavorable (2.12e-5)" "unprognostic (1.77e-3)" "unprognostic (2.81e-2)" "potential prognostic unfavorable (1.84e-4)" "unprognostic (4.20e-3)" "unprognostic (2.39e-1)" "unprognostic (2.20e-1)" "unprognostic (2.97e-1)" "unprognostic (2.69e-2)" "unprognostic (8.62e-2)" "unprognostic (2.96e-2)" "unprognostic (1.38e-1)" "unprognostic (7.73e-2)" "unprognostic (6.14e-2)" "unprognostic (1.15e-1)" "unprognostic (1.73e-1)" "unprognostic (2.29e-1)" "unprognostic (9.19e-2)" ACE "ACE1, CD143, DCP1" ENSG00000159640 "Angiotensin I converting enzyme" P12821 17 63477061-63498380 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Calmodulin-binding, Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 249.7;testis: 96.4" "Group enriched" "Detected in some" 4 "Enterocytes: 90.1;Late spermatids: 55.1" "Cell type enhanced" "Detected in many" "endothelial cell: 5.9;medium spiny neuron: 7.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.0" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Neuroblastoma: 17.2" "Adipose subcutaneous - Adipose progenitor cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Pituitary gland - Corticotropes, Prostate - Prostate glandular cells, Stomach - Fibroblasts, Testis - Late spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002426, CAB002921, HPA029298, HPA069790" Enhanced Approved Vesicles "Secreted to blood" Enzyme NA NA 104000000 59000000 "Cluster 14: Non-specific - Unknown function" "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 33: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 1: Enterocytes - Absorption and Digestion" 4 Vesicles "CAB002426: , CAB002921: , HPA029298: , HPA069790: " "unprognostic (2.23e-1)" "unprognostic (1.27e-1)" "unprognostic (3.07e-2)" "unprognostic (4.01e-1)" "unprognostic (4.10e-2)" "unprognostic (1.37e-1)" "unprognostic (2.68e-1)" "unprognostic (4.46e-1)" "unprognostic (2.64e-2)" "unprognostic (1.90e-1)" "validated prognostic favorable (2.65e-5)" "validated prognostic favorable (2.01e-4)" "unprognostic (4.85e-2)" "unprognostic (2.77e-1)" "unprognostic (2.62e-1)" "unprognostic (4.24e-2)" "unprognostic (1.67e-1)" "unprognostic (9.69e-3)" "unprognostic (1.32e-1)" "unprognostic (6.25e-2)" "unprognostic (1.21e-1)" "unprognostic (3.02e-2)" "unprognostic (1.46e-1)" "unprognostic (3.16e-1)" "unprognostic (1.32e-1)" "unprognostic (1.41e-1)" "unprognostic (2.71e-1)" "unprognostic (6.94e-2)" "unprognostic (1.84e-1)" "unprognostic (1.12e-1)" "unprognostic (2.92e-2)" ACE2 ACEH ENSG00000130234 "Angiotensin converting enzyme 2" Q9BYF1 X 15494566-15607236 "Enzymes, Metabolic proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Host-virus interaction" "Carboxypeptidase, Host cell receptor for virus entry, Hydrolase, Metalloprotease, Protease, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 62.3;intestine: 230.5;kidney: 82.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 29.6;Enterocytes: 264.8;Proximal tubule cells: 54.4;Tuft cells: 34.6;Vascular endothelial cells: 68.0" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 4.3;ependymal cell: 3.0" "Group enriched" "Detected in many" 5 "Colon Adenocarcinoma (TCGA): 21.2;Kidney Renal Clear Cell Carcinoma (TCGA): 39.8;Kidney Renal Papillary Cell Carcinoma (TCGA): 68.1;Rectum Adenocarcinoma (TCGA): 23.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "ovarian cancer: 6.3" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA000288, CAB026174, CAB026213, CAB080024, CAB080025, CAB080027, CAB080028" Enhanced "Secreted to blood" Receptor NA NA 4530000 220000 "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 36: Choroid plexus - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 301 "CAB026174: , CAB026213: , CAB080024: , CAB080025: , CAB080027: , CAB080028: , HPA000288: " "unprognostic (7.16e-2)" "unprognostic (3.85e-2)" "unprognostic (6.99e-2)" "unprognostic (2.71e-1)" "unprognostic (4.58e-2)" "unprognostic (1.78e-2)" "unprognostic (2.84e-2)" "potential prognostic favorable (1.88e-10)" "unprognostic (1.09e-3)" "unprognostic (1.90e-2)" "unprognostic (1.89e-3)" "unprognostic (7.21e-2)" "unprognostic (1.11e-1)" "unprognostic (2.99e-1)" "unprognostic (6.16e-3)" "unprognostic (1.51e-1)" "unprognostic (6.11e-2)" "unprognostic (1.54e-2)" "unprognostic (1.06e-2)" "unprognostic (9.30e-3)" "unprognostic (2.21e-2)" "unprognostic (8.84e-2)" "unprognostic (2.70e-1)" ACER1 ASAH3 ENSG00000167769 "Alkaline ceramidase 1" Q8TDN7 19 6306142-6333612 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "skin 1: 85.7" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 8.1;Early primary spermatocytes: 17.3;Esophageal apical cells: 75.8;Suprabasal keratinocytes: 14.5;T-cells: 9.4;Thymocytes: 31.3" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 6.5" "Cancer enhanced" "Detected in some" "Skin Cutaneous Melanoma (TCGA): 3.3" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Lineage enriched" "Detected in single" 4 "T-cells: 1.2" "Cancer enhanced" "Detected in single" "prostate cancer: 1.1" "Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Prostate glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 37: Skin - Keratinization" "Cluster 48: Non-specific - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 1 "unprognostic (1.39e-3)" "unprognostic (3.80e-1)" "unprognostic (3.07e-2)" ACER2 "ALKCDase2, ASAH3L, FLJ41587" ENSG00000177076 "Alkaline ceramidase 2" Q5QJU3 9 19409009-19452505 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "stomach 1: 58.3;urinary bladder: 36.7" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 215.3;Foveolar cells: 748.9;Papillary tip epithelial cells: 771.3;Prostatic club cells: 374.8;Prostatic hillock cells: 331.2;Syncytiotrophoblasts: 241.5;Urothelial cells: 1313.9" "Cell type enhanced" "Detected in all" "endothelial cell: 204.4" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 16.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Colon - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 60: Stomach - Digestion" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 69: Urothelial cells - Basic cellular functions" "unprognostic (3.84e-2)" "unprognostic (1.51e-1)" "unprognostic (1.54e-1)" "unprognostic (1.83e-1)" "unprognostic (1.51e-1)" "unprognostic (5.28e-3)" "unprognostic (1.89e-1)" "unprognostic (2.62e-1)" "unprognostic (1.81e-1)" "validated prognostic favorable (5.97e-9)" "validated prognostic favorable (4.78e-6)" "unprognostic (4.10e-1)" "unprognostic (3.02e-2)" "unprognostic (9.01e-3)" "unprognostic (4.31e-2)" "unprognostic (1.84e-1)" "unprognostic (1.99e-1)" "unprognostic (1.72e-1)" "unprognostic (1.43e-1)" "unprognostic (5.58e-2)" "unprognostic (2.81e-2)" "unprognostic (1.79e-1)" "unprognostic (2.23e-2)" "unprognostic (8.50e-2)" "unprognostic (1.75e-1)" "unprognostic (7.88e-2)" "unprognostic (9.44e-2)" ACER3 "APHC, FLJ11238, PHCA" ENSG00000078124 "Alkaline ceramidase 3" Q9NUN7 11 76860859-77026797 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Mast cells: 568.3;Neutrophil progenitors: 336.7;Neutrophils: 360.5;Oligodendrocytes: 400.5" "Cell type enhanced" "Detected in all" "oligodendrocyte: 531.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070087 Approved NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 58: Mast cells - Allergic inflammatory responses" "HPA070087: " "unprognostic (1.25e-1)" "unprognostic (1.07e-1)" "unprognostic (1.07e-2)" "unprognostic (8.92e-3)" "unprognostic (3.40e-3)" "potential prognostic unfavorable (8.67e-4)" "unprognostic (5.03e-2)" "unprognostic (9.38e-3)" "unprognostic (4.96e-2)" "unprognostic (2.16e-2)" "unprognostic (8.78e-3)" "unprognostic (1.89e-1)" "unprognostic (2.03e-1)" "potential prognostic unfavorable (8.30e-4)" "unprognostic (4.71e-2)" "unprognostic (1.55e-2)" "unprognostic (1.59e-2)" "unprognostic (3.77e-2)" "unprognostic (1.66e-1)" "unprognostic (3.23e-2)" "unprognostic (3.64e-2)" "unprognostic (6.79e-2)" "unprognostic (2.64e-1)" "unprognostic (1.20e-2)" "unprognostic (1.31e-1)" "unprognostic (7.51e-2)" "unprognostic (2.13e-3)" "unprognostic (3.31e-1)" "unprognostic (1.49e-1)" "unprognostic (1.20e-2)" "unprognostic (6.38e-2)" ACHE YT ENSG00000087085 "Acetylcholinesterase (Cartwright blood group)" P22303 7 100889994-100896974 "Blood group antigen proteins, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Neurotransmitter degradation" "Blood group antigen, Hydrolase, Serine esterase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "brain: 103.9;skeletal muscle: 152.9;tongue: 44.9" "Cell type enhanced" "Detected in many" "Colonocytes: 78.6;Enterocytes: 122.4;Myonuclei: 35.2;Other brain neurons: 59.6;Retinal amacrine cells: 48.9;Retinal ganglion cells: 42.5;Retinal horizontal cells: 50.1;Thymic myoid cells: 35.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pituitary gland - Gonadotropes, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027098 Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" Enzyme NA NA 1100000 "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 47: Leukemia - Hemostasis" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 3 "Golgi apparatus" Vesicles "HPA027098: " "unprognostic (8.14e-3)" "unprognostic (2.08e-3)" "unprognostic (1.36e-1)" "unprognostic (2.03e-2)" "unprognostic (3.35e-2)" "potential prognostic unfavorable (2.24e-5)" "unprognostic (7.48e-2)" "unprognostic (1.68e-1)" "potential prognostic unfavorable (5.51e-5)" "unprognostic (1.66e-3)" "unprognostic (1.32e-1)" "unprognostic (2.02e-1)" "potential prognostic unfavorable (2.58e-5)" "potential prognostic favorable (5.01e-4)" "unprognostic (1.15e-1)" "unprognostic (3.29e-2)" "unprognostic (1.00e-1)" "unprognostic (2.62e-2)" "unprognostic (1.22e-1)" "unprognostic (2.33e-1)" "unprognostic (1.08e-1)" "unprognostic (2.03e-2)" "unprognostic (3.58e-1)" "unprognostic (4.15e-2)" "unprognostic (7.51e-3)" ACIN1 "ACINUS, fSAP152, KIAA0670" ENSG00000100813 "Apoptotic chromatin condensation inducer 1" Q9UKV3 14 23058564-23095614 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Apoptosis, mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000657 Supported Supported Nucleoplasm,Cytosol NA NA 80000 "Cluster 20: Non-specific - DNA binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 17: Non-specific - RNA processing" 83 Nucleoplasm Cytosol "HPA000657: " "unprognostic (1.03e-1)" "unprognostic (4.09e-2)" "unprognostic (9.51e-2)" "unprognostic (1.12e-2)" "unprognostic (1.78e-2)" "unprognostic (2.29e-1)" "unprognostic (1.89e-1)" "unprognostic (6.01e-3)" "unprognostic (1.36e-1)" "unprognostic (3.46e-2)" "unprognostic (2.03e-1)" "unprognostic (4.46e-2)" "unprognostic (1.99e-2)" "potential prognostic unfavorable (3.52e-6)" "unprognostic (3.70e-2)" "unprognostic (1.00e-1)" "unprognostic (7.38e-3)" "unprognostic (4.91e-2)" "unprognostic (7.90e-3)" "unprognostic (3.74e-1)" "unprognostic (9.48e-3)" "potential prognostic favorable (9.76e-4)" "unprognostic (1.20e-2)" "unprognostic (3.61e-2)" "unprognostic (1.68e-1)" "unprognostic (1.83e-1)" "unprognostic (1.80e-2)" "unprognostic (2.44e-1)" "unprognostic (2.32e-2)" "unprognostic (8.13e-2)" "unprognostic (2.70e-2)" ACKR1 "CCBP1, CD234, DARC, Dfy, FY, GPD" ENSG00000213088 "Atypical chemokine receptor 1 (Duffy blood group)" Q16570 1 159203307-159206500 "Blood group antigen proteins, CD markers, G-protein coupled receptors, Predicted membrane proteins, Transporters" "Blood group antigen, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 387.8;breast: 337.2" "Cell type enriched" "Detected in many" 16 "Vascular endothelial cells: 896.0" "Cell type enhanced" "Detected in many" "endothelial cell: 48.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bile duct cancer: 5.8;Brain cancer: 1.7;Leukemia: 1.5;Neuroblastoma: 2.2;skin cancer: 2.2" "Breast - Endothelial cells, Colon - Endothelial cells, Minor Salivary Gland - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016421, HPA017672" Enhanced NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 35: Non-specific - DNA binding" "Cluster 47: Leukemia - Hemostasis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "HPA016421: , HPA017672: " "unprognostic (5.81e-2)" "unprognostic (2.83e-2)" "potential prognostic favorable (6.37e-5)" "unprognostic (6.93e-2)" "unprognostic (6.41e-2)" "unprognostic (2.62e-2)" "unprognostic (4.36e-2)" "unprognostic (6.62e-3)" "unprognostic (5.11e-2)" "unprognostic (4.55e-3)" "potential prognostic favorable (9.58e-4)" "unprognostic (2.70e-1)" "potential prognostic favorable (9.81e-5)" "unprognostic (2.15e-3)" "unprognostic (1.58e-1)" "unprognostic (7.69e-2)" "unprognostic (5.53e-2)" "unprognostic (7.40e-2)" "unprognostic (1.43e-1)" "unprognostic (1.25e-3)" "unprognostic (9.70e-2)" "unprognostic (9.11e-2)" "unprognostic (2.69e-1)" "unprognostic (5.92e-2)" "unprognostic (1.31e-1)" "unprognostic (4.97e-3)" "unprognostic (1.15e-1)" "unprognostic (2.04e-2)" "unprognostic (3.05e-1)" ACKR2 "CCBP2, CCR10, CCR9, CMKBR9, D6" ENSG00000144648 "Atypical chemokine receptor 2" O00590 3 42804752-42887974 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 8.8;placenta: 15.0" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 10.6;Colonocytes: 9.5;Early primary spermatocytes: 6.5;Enterocytes: 10.9;Ependymal cells: 7.1;Extravillous trophoblasts: 9.3;Syncytiotrophoblasts: 6.2;Undifferentiated spermatogonia: 9.4" "Cell type enhanced" "Detected in many" "ependymal cell: 7.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "eosinophil: 3.8;NK-cell: 1.0" "Group enriched" "Detected in many" 7 "granulocytes: 3.8;NK-cells: 1.0" "Low cancer specificity" "Detected in some" "Group enriched" "Detected in many" 5 "amygdala: 2.2;basal ganglia: 7.9;cerebral cortex: 4.9;hippocampal formation: 2.4" "Low region specificity" "Detected in all" "HPA013819, HPA073493" Enhanced Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 6: Non-specific - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 65: Non-specific - Cell growth & division" 51 "Vesicles, Cytosol" Nucleoplasm "HPA013819: , HPA073493: " "unprognostic (2.50e-2)" "unprognostic (1.17e-2)" "unprognostic (1.00e-1)" "unprognostic (1.69e-1)" "unprognostic (3.10e-1)" "unprognostic (7.82e-3)" "unprognostic (7.14e-2)" "unprognostic (3.29e-1)" "unprognostic (3.41e-3)" "unprognostic (1.59e-1)" "unprognostic (3.37e-2)" "unprognostic (8.85e-3)" "unprognostic (3.30e-1)" "unprognostic (4.97e-2)" "unprognostic (8.63e-2)" "unprognostic (6.37e-2)" "unprognostic (9.77e-2)" "unprognostic (1.28e-1)" "unprognostic (2.88e-2)" "unprognostic (1.66e-2)" "unprognostic (2.06e-1)" ACKR3 "CMKOR1, CXCR7, GPR159, RDC1" ENSG00000144476 "Atypical chemokine receptor 3" P25106 2 236567787-236582354 "Cancer-related genes, Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial luminal cells: 59.0;Fibro-adipogenic progenitors: 150.0;Fibroblasts: 192.3;Lymphatic endothelial cells: 174.0;Respiratory ionocytes: 73.7;Schwann cells: 116.4;Vascular smooth muscle cells: 182.8" "Cell type enhanced" "Detected in many" "astrocyte: 66.2;vascular associated smooth muscle cell: 193.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "NK-cells: 4.7;T-cells: 3.8" "Cancer enhanced" "Detected in many" "Kidney cancer: 106.8" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032003, HPA049718" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 39: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 108: Fibroblasts - ECM organization" 6 "Vesicles, Plasma membrane" "HPA032003: , HPA049718: " "unprognostic (1.51e-1)" "unprognostic (1.62e-3)" "unprognostic (2.01e-3)" "unprognostic (2.34e-1)" "unprognostic (1.30e-2)" "unprognostic (2.57e-1)" "unprognostic (1.91e-3)" "unprognostic (2.56e-1)" "unprognostic (3.88e-2)" "unprognostic (3.68e-1)" "unprognostic (2.00e-2)" "unprognostic (5.10e-2)" "unprognostic (1.83e-3)" "unprognostic (2.98e-2)" "unprognostic (5.82e-3)" "unprognostic (1.60e-1)" "unprognostic (3.56e-2)" "unprognostic (6.38e-2)" "unprognostic (1.57e-1)" "unprognostic (1.48e-3)" "unprognostic (6.04e-2)" "unprognostic (3.76e-2)" "unprognostic (1.21e-1)" "unprognostic (3.07e-3)" "unprognostic (6.33e-3)" "potential prognostic unfavorable (1.37e-4)" "unprognostic (1.46e-1)" "unprognostic (1.96e-3)" "unprognostic (1.57e-1)" ACKR4 "CCBP2, CCR11, CCRL1, CCX-CKR, PPR1, VSHK1" ENSG00000129048 "Atypical chemokine receptor 4" Q9NPB9 3 132597270-132618967 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 14.8" "Cell type enhanced" "Detected in many" "Adipocytes: 59.1;Cardiomyocytes: 85.4;Epicardial cells: 45.5;Fibro-adipogenic progenitors: 32.2;Foveolar cells: 20.0;Lymphatic endothelial cells: 19.5;Myonuclei: 30.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lymphoma: 4.4" "Group enriched" "Detected in some" 7 "cerebellum: 4.7;pons and medulla: 1.5" "Low region specificity" "Detected in all" HPA054926 Approved Vesicles,Mitochondria NA NA "Cluster 77: Intestine - Digestion" "Cluster 17: Choroid plexus - Cilium" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 89: Adipocytes - Lipid metabolism" "Vesicles, Mitochondria" "HPA054926: " "unprognostic (6.09e-2)" "unprognostic (3.86e-2)" "unprognostic (1.31e-2)" "unprognostic (2.18e-2)" "unprognostic (9.43e-2)" "unprognostic (8.49e-3)" "unprognostic (2.03e-1)" "unprognostic (4.58e-3)" "unprognostic (1.45e-1)" "unprognostic (1.16e-2)" "unprognostic (1.01e-1)" "unprognostic (8.76e-2)" "unprognostic (2.05e-1)" "unprognostic (2.11e-2)" "potential prognostic favorable (1.50e-4)" "potential prognostic unfavorable (2.95e-4)" "unprognostic (3.34e-2)" "unprognostic (1.04e-1)" "unprognostic (1.51e-1)" "unprognostic (2.08e-1)" ACLY "ACL, ATPCL, CLATP" ENSG00000131473 "ATP citrate lyase" P53396 17 41866917-41930542 "Cancer-related genes, Citric acid cycle related proteins, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism" Transferase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreatic islet cells: 201.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Macrophages, Prostate - Prostate glandular cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007783, HPA022434, HPA022953, HPA022959, HPA028758" Enhanced Supported "Nucleoplasm,Primary cilium transition zone,Basal body,Cytosol,Principal piece" No No 4000000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 43: Hindbrain - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 39 Cytosol "Nucleoplasm, Primary cilium transition zone, Basal body, Principal piece" "CAB007783: , HPA022434: , HPA022953: , HPA022959: , HPA028758: " "unprognostic (1.22e-1)" "unprognostic (3.18e-2)" "unprognostic (5.18e-2)" "potential prognostic unfavorable (5.56e-4)" "unprognostic (1.55e-1)" "unprognostic (1.06e-1)" "unprognostic (2.26e-1)" "unprognostic (2.47e-1)" "unprognostic (3.33e-2)" "potential prognostic unfavorable (4.59e-5)" "potential prognostic favorable (1.58e-6)" "unprognostic (1.50e-3)" "unprognostic (1.02e-1)" "unprognostic (1.90e-3)" "unprognostic (6.07e-3)" "unprognostic (5.74e-3)" "unprognostic (2.90e-2)" "unprognostic (2.48e-1)" "unprognostic (2.26e-1)" "unprognostic (4.50e-3)" "unprognostic (1.30e-1)" "unprognostic (3.87e-2)" "unprognostic (1.96e-1)" "unprognostic (2.16e-2)" "unprognostic (4.99e-2)" "unprognostic (1.31e-2)" "unprognostic (8.45e-2)" "unprognostic (1.16e-1)" "unprognostic (4.67e-1)" "unprognostic (1.89e-2)" "unprognostic (1.45e-1)" ACMSD ENSG00000153086 "Aminocarboxymuconate semialdehyde decarboxylase" Q8TDX5 2 134838616-134902034 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 21 "kidney: 131.6;liver: 151.9" "Group enriched" "Detected in many" 4 "Hepatocytes: 315.2;Proximal tubule cells: 388.4" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 23 "Kidney Renal Clear Cell Carcinoma (TCGA): 69.5;Kidney Renal Papillary Cell Carcinoma (TCGA): 73.1;Liver Hepatocellular Carcinoma (TCGA): 60.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney cancer: 3.6" "Breast - Breast glandular cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA010533, HPA011179" Enhanced Approved Cytosol NA NA "Cluster 16: Liver & Kidney - Metabolism" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 7: Liver cancer - Metabolism" "Cluster 88: Proximal tubular cells - Transmembrane transport" 1 Cytosol "HPA010533: , HPA011179: " "unprognostic (1.44e-1)" "unprognostic (3.14e-1)" "unprognostic (2.06e-2)" "validated prognostic favorable (1.35e-8)" "validated prognostic favorable (3.64e-4)" "unprognostic (5.46e-3)" "unprognostic (8.71e-3)" "unprognostic (3.86e-2)" "unprognostic (5.77e-2)" "unprognostic (1.89e-1)" "unprognostic (1.76e-2)" "unprognostic (3.04e-1)" "unprognostic (8.85e-2)" ACO1 "IREB1, IREBP, IRP1" ENSG00000122729 "Aconitase 1" P21399 9 32384603-32454769 "Cancer-related genes, Citric acid cycle related proteins, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" "Lyase, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 125.8" "Cell type enhanced" "Detected in many" "Adipocytes: 270.8;Hepatocytes: 236.0;Proximal tubule cells: 177.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Smooth muscle cells, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019371, HPA024157" Enhanced Supported Mitochondria,Cytosol NA NA 9700000 "Cluster 41: Basophils - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 89: Adipocytes - Lipid metabolism" 6 "Mitochondria, Cytosol" "HPA019371: , HPA024157: " "unprognostic (1.00e-1)" "unprognostic (1.12e-1)" "unprognostic (1.25e-1)" "unprognostic (8.58e-2)" "unprognostic (5.20e-3)" "unprognostic (5.40e-2)" "unprognostic (1.66e-1)" "unprognostic (7.24e-3)" "unprognostic (2.62e-2)" "unprognostic (1.34e-1)" "potential prognostic favorable (1.17e-6)" "unprognostic (7.98e-2)" "unprognostic (1.26e-1)" "unprognostic (1.06e-2)" "potential prognostic favorable (4.08e-4)" "unprognostic (3.01e-1)" "unprognostic (3.43e-2)" "unprognostic (2.01e-1)" "unprognostic (2.05e-1)" "unprognostic (5.86e-2)" "unprognostic (1.08e-1)" "unprognostic (1.11e-1)" "unprognostic (2.67e-2)" "unprognostic (2.28e-1)" "unprognostic (2.15e-1)" "unprognostic (9.95e-2)" "unprognostic (2.92e-1)" "unprognostic (2.84e-1)" "unprognostic (5.56e-2)" "unprognostic (3.71e-1)" "unprognostic (1.66e-1)" ACO2 ACONM ENSG00000100412 "Aconitase 2" Q99798 22 41447830-41529273 "Citric acid cycle related proteins, Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" Lyase "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 463.1;skeletal muscle: 618.6;tongue: 650.0" "Cell type enhanced" "Detected in many" "Enterocytes: 479.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001097 Enhanced Approved Approved Mitochondria NA NA 2500000 "Cluster 14: Non-specific - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 14: Neurons - Synaptic function" "Cluster 66: Non-specific - Mitochondria" "Cluster 97: Non-specific - Cellular respiration" 10 Mitochondria "HPA001097: " "unprognostic (6.26e-2)" "unprognostic (1.18e-1)" "unprognostic (5.08e-2)" "unprognostic (4.03e-2)" "unprognostic (2.79e-2)" "unprognostic (2.91e-1)" "unprognostic (5.24e-2)" "unprognostic (1.92e-1)" "unprognostic (3.79e-1)" "unprognostic (3.72e-2)" "validated prognostic favorable (8.29e-13)" "validated prognostic favorable (3.32e-4)" "potential prognostic favorable (1.15e-5)" "unprognostic (1.37e-2)" "unprognostic (8.50e-3)" "unprognostic (1.12e-2)" "unprognostic (3.90e-2)" "unprognostic (2.95e-2)" "unprognostic (5.45e-3)" "unprognostic (4.42e-2)" "unprognostic (2.02e-1)" "unprognostic (8.20e-2)" "unprognostic (5.38e-3)" "unprognostic (1.90e-1)" "unprognostic (1.26e-1)" "unprognostic (2.15e-1)" "unprognostic (1.14e-3)" "unprognostic (3.44e-2)" "unprognostic (8.31e-2)" "unprognostic (1.67e-1)" "unprognostic (2.93e-1)" ACOD1 "CAD, IRG1" ENSG00000102794 "Aconitate decarboxylase 1" A6NK06 13 76948511-76958638 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Immunity, Inflammatory response, Innate immunity" "Antimicrobial, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.3" "Cell type enriched" "Detected in some" 18 "monocytes: 54.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA040143, HPA058816" Uncertain Uncertain Nucleoplasm,Mitochondria NA NA "Cluster 66: Lymphoid tissue - Immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" Mitochondria Nucleoplasm "HPA040143: , HPA058816: " ACOT1 "ACH2, CTE-1, LACH2" ENSG00000184227 "Acyl-CoA thioesterase 1" Q86TX2 14 73537143-73543796 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 41.6" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 10.6;Breast lactating cells: 36.6;Breast myoepithelial cells: 21.5;Cardiomyocytes: 12.7;Epididymal clear cells: 22.5;Epididymal principal cells: 66.5" "Cell type enhanced" "Detected in many" "Bergmann glia: 5.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Skin - Sebaceous gland cells" HPA043705 Approved Approved Mitochondria NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 27: Breast cancer - Unknown function" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 8 Mitochondria "HPA043705: " "unprognostic (1.85e-1)" "unprognostic (1.41e-3)" "unprognostic (3.02e-3)" "unprognostic (6.96e-3)" "unprognostic (2.62e-1)" "unprognostic (5.36e-2)" "unprognostic (1.81e-2)" "unprognostic (1.03e-2)" "unprognostic (1.74e-1)" "unprognostic (3.14e-1)" "potential prognostic favorable (2.47e-5)" "unprognostic (2.36e-2)" "unprognostic (1.32e-2)" "unprognostic (3.69e-2)" "unprognostic (6.89e-2)" "unprognostic (1.56e-1)" "unprognostic (2.63e-1)" "unprognostic (4.64e-2)" "unprognostic (1.31e-1)" "unprognostic (1.42e-2)" "unprognostic (5.30e-2)" "unprognostic (7.68e-2)" "unprognostic (2.48e-3)" "unprognostic (3.23e-1)" "unprognostic (4.61e-2)" "unprognostic (2.91e-2)" "unprognostic (3.41e-2)" "potential prognostic unfavorable (2.44e-4)" "unprognostic (1.98e-2)" "unprognostic (1.83e-1)" "unprognostic (2.80e-1)" ACOT11 "BFIT, BFIT1, KIAA0707, STARD14, THEA, THEM1" ENSG00000162390 "Acyl-CoA thioesterase 11" Q8WXI4 1 54542257-54639192 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 32.2" "Cell type enhanced" "Detected in many" "Astrocytes: 317.1;Choroid plexus epithelial cells: 640.5;Distal convoluted tubule cells: 269.4;Ependymal cells: 294.8;Myonuclei: 491.3;Pituitary stem cells: 251.4;Retinal pigment epithelial cells: 243.0;Somatotrophs: 321.5;Thyrotrophs: 405.8" "Cell type enhanced" "Detected in all" "astrocyte: 368.9;choroid plexus epithelial cell: 415.1;ependymal cell: 285.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 4.5" "Lineage enriched" "Detected in single" 8 "granulocytes: 4.5" "Low cancer specificity" "Detected in all" "Breast - Breast myoepithelial cells, Heart muscle - Cardiomyocytes, Kidney - Ascending Loop of Henle cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041047 Enhanced Supported Cytosol NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 76: Non-specific - Metabolism" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 55: Myocytes - Oxidative muscle function" Cytosol "HPA041047: " "unprognostic (1.04e-1)" "unprognostic (2.28e-1)" "unprognostic (1.70e-1)" "unprognostic (1.05e-2)" "unprognostic (7.27e-3)" "unprognostic (6.88e-2)" "unprognostic (6.36e-2)" "unprognostic (3.22e-1)" "unprognostic (8.67e-2)" "unprognostic (2.68e-3)" "unprognostic (1.65e-2)" "unprognostic (8.32e-2)" "potential prognostic favorable (4.75e-4)" "unprognostic (9.12e-3)" "unprognostic (6.93e-3)" "unprognostic (4.48e-2)" "unprognostic (2.77e-1)" "unprognostic (6.79e-3)" "unprognostic (3.11e-1)" "unprognostic (2.25e-2)" "unprognostic (3.20e-2)" "unprognostic (2.47e-1)" "unprognostic (3.52e-2)" "unprognostic (1.14e-1)" "unprognostic (1.63e-1)" "unprognostic (1.27e-1)" "unprognostic (2.36e-1)" "unprognostic (2.45e-1)" "unprognostic (4.92e-1)" "unprognostic (1.35e-2)" "unprognostic (5.83e-2)" ACOT12 "Cach, STARD15, THEAL" ENSG00000172497 "Acyl-CoA thioesterase 12" Q8WYK0 5 81329996-81394179 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Transporters" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 36 "liver: 94.1" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 12.9;Hepatocytes: 80.1;pDCs: 15.2;Renal collecting duct principal cells: 18.9;Thymocytes: 66.1" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in single" 43 "Liver Hepatocellular Carcinoma (TCGA): 19.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "liver cancer: 1.1" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA037723 Approved "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 14: Neurons - Synaptic function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 8 Cytosol "Nucleoplasm, Cytokinetic bridge" "HPA037723: " "unprognostic (1.62e-3)" "validated prognostic favorable (3.77e-4)" "validated prognostic favorable (1.92e-4)" ACOT13 "HT012, THEM2" ENSG00000112304 "Acyl-CoA thioesterase 13" Q9NPJ3 6 24667035-24705065 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 28.6" "Cell type enhanced" "Detected in many" "Early spermatids: 1133.8;Hepatocytes: 232.6;Late primary spermatocytes: 448.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019881, HPA057134" Enhanced Approved "Cell Junctions" NA NA 8200 "Cluster 33: Non-specific - ATP binding" "Cluster 76: Non-specific - Metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 6 "Cell Junctions" "HPA019881: , HPA057134: " "unprognostic (1.46e-1)" "unprognostic (1.10e-3)" "unprognostic (4.09e-1)" "unprognostic (2.34e-1)" "unprognostic (2.78e-1)" "potential prognostic favorable (6.39e-4)" "unprognostic (1.59e-1)" "unprognostic (2.53e-2)" "unprognostic (2.27e-2)" "unprognostic (9.37e-2)" "potential prognostic favorable (2.05e-7)" "unprognostic (7.83e-3)" "unprognostic (1.51e-2)" "unprognostic (3.50e-1)" "unprognostic (1.33e-2)" "unprognostic (8.91e-2)" "unprognostic (3.26e-2)" "unprognostic (4.57e-2)" "unprognostic (8.65e-2)" "potential prognostic favorable (1.30e-4)" "unprognostic (3.85e-1)" "unprognostic (1.38e-2)" "unprognostic (3.94e-1)" "unprognostic (2.45e-2)" "unprognostic (6.70e-2)" "potential prognostic unfavorable (2.54e-4)" "unprognostic (1.19e-1)" "unprognostic (1.13e-1)" "unprognostic (1.15e-1)" "unprognostic (4.13e-1)" "unprognostic (6.16e-2)" ACOT2 "Mte1, ZAP128" ENSG00000119673 "Acyl-CoA thioesterase 2" P49753 14 73567620-73575658 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 53.8;Epididymal efferent duct absorptive cells: 51.5;Epididymal principal cells: 40.6;Megakaryocytes: 37.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Prostate - Smooth muscle cells, Testis - Sertoli cells" "HPA043705, HPA060170" Enhanced Approved Mitochondria NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 76: Non-specific - Metabolism" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 15: Non-specific - Protein processing" 7 Mitochondria "HPA043705: , HPA060170: " "unprognostic (8.04e-2)" "unprognostic (1.05e-2)" "unprognostic (2.16e-2)" "unprognostic (1.54e-3)" "unprognostic (3.28e-1)" "unprognostic (8.27e-2)" "unprognostic (3.18e-2)" "unprognostic (2.69e-1)" "unprognostic (2.36e-1)" "unprognostic (4.15e-1)" "potential prognostic favorable (4.10e-4)" "unprognostic (2.60e-2)" "unprognostic (1.66e-2)" "unprognostic (3.99e-2)" "unprognostic (3.10e-1)" "unprognostic (5.62e-2)" "unprognostic (1.32e-1)" "unprognostic (2.69e-1)" "unprognostic (1.04e-1)" "unprognostic (2.92e-1)" "unprognostic (9.47e-2)" "unprognostic (6.70e-2)" "unprognostic (5.13e-2)" "unprognostic (1.23e-1)" "unprognostic (4.39e-1)" "unprognostic (4.74e-2)" "unprognostic (4.38e-1)" "potential prognostic unfavorable (9.34e-4)" "unprognostic (3.65e-2)" "unprognostic (2.05e-3)" "unprognostic (2.89e-1)" ACOT4 "FLJ31235, PTE-Ib, PTE2B" ENSG00000177465 "Acyl-CoA thioesterase 4" Q8N9L9 14 73591873-73595766 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 14.0;liver: 15.6" "Cell type enhanced" "Detected in some" "Astrocytes: 1.3;Bergmann glia: 1.2;Brain excitatory neurons: 1.8;Brain inhibitory neurons: 1.6;Other brain neurons: 1.6;Proximal tubule cells: 1.0;Renal collecting duct intercalated cells: 2.0;Renal collecting duct principal cells: 1.0;Smooth muscle cells: 2.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 18.6;breast cancer: 15.7" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Macrophages" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA000779 Enhanced NA NA "Cluster 1: T-cells - Unknown function" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" "HPA000779: " "unprognostic (2.42e-1)" "unprognostic (6.38e-3)" "unprognostic (7.09e-2)" "potential prognostic favorable (3.19e-4)" "unprognostic (8.38e-2)" "unprognostic (3.61e-1)" "unprognostic (3.08e-1)" "unprognostic (5.16e-2)" "unprognostic (3.83e-1)" "unprognostic (3.81e-2)" "potential prognostic favorable (3.00e-7)" "unprognostic (8.55e-3)" "potential prognostic favorable (3.18e-5)" "unprognostic (3.01e-2)" "unprognostic (2.49e-2)" "unprognostic (1.06e-1)" "unprognostic (1.73e-2)" "unprognostic (1.68e-1)" "unprognostic (3.55e-1)" "unprognostic (1.66e-1)" "unprognostic (1.36e-1)" "unprognostic (2.98e-3)" "unprognostic (3.02e-1)" "unprognostic (3.54e-1)" "unprognostic (1.91e-1)" "unprognostic (1.99e-3)" "unprognostic (1.72e-1)" "unprognostic (2.58e-1)" "unprognostic (1.03e-1)" "unprognostic (3.92e-1)" "unprognostic (1.73e-1)" ACOT6 C14orf42 ENSG00000205669 "Acyl-CoA thioesterase 6" Q3I5F7 14 73610945-73619888 "Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 3.4;liver: 3.0;skeletal muscle: 3.7" "Cell type enhanced" "Detected in some" "Adipocytes: 21.5;Astrocytes: 5.4;Bergmann glia: 7.2;Brain excitatory neurons: 5.2;Cardiomyocytes: 28.0;Hepatocytes: 7.7;Myonuclei: 13.6;Proximal tubule cells: 5.8" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Kidney Chromophobe (TCGA): 3.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "breast cancer: 2.3" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058258 Uncertain NA NA "Cluster 16: Liver & Kidney - Metabolism" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Breast cancer - Unknown function" "Cluster 89: Adipocytes - Lipid metabolism" 2 "HPA058258: " "unprognostic (1.33e-2)" "unprognostic (2.44e-1)" "unprognostic (1.71e-1)" "unprognostic (7.51e-2)" "unprognostic (5.97e-3)" "unprognostic (8.24e-3)" ACOT7 "ACH1, ACT, BACH, CTE-II, hBACH, LACH1, MGC1126" ENSG00000097021 "Acyl-CoA thioesterase 7" O00154 1 6264269-6393767 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 140.7" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 144.9;Enterocytes: 172.1;Goblet cells: 159.1;Late spermatids: 213.7;Mast cells: 161.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "NK-cell: 40.3;plasmacytoid DC: 35.8" "Group enriched" "Detected in many" 5 "dendritic cells: 35.8;NK-cells: 40.3" "Low cancer specificity" "Detected in all" "Colon - Colon enteroendocrine cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Pituitary gland - Lactotropes, Skin - Inner root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025735, HPA025762" Enhanced Supported Cytosol No No 62000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 1: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 70: Intestinal goblet cells - Mucin production" 13 Cytosol "HPA025735: , HPA025762: " "unprognostic (7.15e-2)" "unprognostic (3.96e-2)" "unprognostic (1.71e-2)" "unprognostic (4.31e-2)" "unprognostic (2.07e-2)" "unprognostic (1.27e-1)" "unprognostic (5.05e-3)" "unprognostic (7.41e-2)" "unprognostic (6.46e-2)" "unprognostic (3.29e-3)" "unprognostic (1.27e-2)" "unprognostic (1.25e-1)" "unprognostic (1.08e-2)" "validated prognostic unfavorable (8.35e-5)" "validated prognostic unfavorable (3.56e-6)" "potential prognostic unfavorable (1.17e-5)" "unprognostic (5.52e-2)" "unprognostic (4.90e-2)" "unprognostic (4.28e-2)" "unprognostic (1.40e-1)" "unprognostic (1.63e-1)" "unprognostic (5.89e-2)" "unprognostic (5.07e-2)" "unprognostic (1.31e-2)" "unprognostic (1.23e-1)" "unprognostic (3.49e-2)" "unprognostic (5.67e-2)" "unprognostic (1.28e-2)" "unprognostic (2.27e-1)" "unprognostic (7.50e-2)" "unprognostic (8.48e-2)" ACOT8 "hACTE-III, hTE, NAP1, PTE-2, PTE1" ENSG00000101473 "Acyl-CoA thioesterase 8" O14734 20 45841721-45857405 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Host-virus interaction, Lipid metabolism, Peroxisome biogenesis" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 93.2;Enterocytes: 97.7;Esophageal apical cells: 99.9;Late spermatids: 145.8;Parietal cells: 123.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010261 Approved Supported Vesicles,Mitochondria NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 52: Non-specific - Cellular respiration" "Cluster 14: Neurons - Synaptic function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 9 Vesicles Mitochondria "CAB010261: " "unprognostic (1.20e-1)" "unprognostic (1.06e-3)" "unprognostic (7.17e-2)" "unprognostic (6.70e-2)" "unprognostic (2.78e-1)" "unprognostic (3.25e-1)" "unprognostic (1.54e-2)" "unprognostic (2.22e-3)" "unprognostic (3.30e-2)" "unprognostic (5.96e-3)" "unprognostic (1.75e-1)" "unprognostic (1.02e-2)" "unprognostic (6.23e-3)" "validated prognostic unfavorable (4.45e-5)" "validated prognostic unfavorable (7.03e-5)" "unprognostic (6.20e-2)" "unprognostic (9.53e-2)" "unprognostic (9.75e-2)" "unprognostic (3.59e-2)" "unprognostic (3.14e-1)" "unprognostic (4.05e-2)" "unprognostic (1.20e-1)" "unprognostic (1.10e-1)" "unprognostic (6.78e-3)" "unprognostic (5.59e-2)" "unprognostic (4.42e-2)" "unprognostic (3.05e-1)" "unprognostic (1.53e-1)" "unprognostic (2.11e-1)" "unprognostic (3.66e-1)" "unprognostic (3.62e-1)" ACOT9 "ACATE2, CGI-16, MT-ACT48" ENSG00000123130 "Acyl-CoA thioesterase 9" Q9Y305 X 23701055-23766475 "Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "cDC: 123.6;monocytes: 161.2;Neutrophils: 212.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035533 Supported Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 9500 "Cluster 40: Monocytes - Innate immune response" "Cluster 35: Non-specific - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 8 "Plasma membrane, Cytosol" Nucleoplasm "HPA035533: " "unprognostic (9.21e-2)" "unprognostic (5.15e-2)" "unprognostic (6.18e-2)" "unprognostic (1.07e-1)" "unprognostic (4.17e-2)" "unprognostic (2.56e-1)" "unprognostic (1.92e-1)" "unprognostic (1.58e-3)" "unprognostic (1.92e-3)" "unprognostic (1.47e-2)" "unprognostic (2.85e-2)" "unprognostic (4.79e-1)" "unprognostic (1.42e-1)" "potential prognostic unfavorable (4.02e-4)" "unprognostic (2.41e-1)" "unprognostic (4.36e-2)" "unprognostic (1.89e-3)" "unprognostic (3.23e-2)" "unprognostic (1.56e-1)" "unprognostic (9.29e-2)" "unprognostic (3.21e-2)" "potential prognostic unfavorable (6.50e-4)" "unprognostic (8.48e-3)" "unprognostic (2.16e-1)" "unprognostic (1.08e-1)" "unprognostic (8.37e-3)" "unprognostic (1.81e-1)" "unprognostic (1.36e-2)" "unprognostic (1.41e-1)" "unprognostic (1.52e-1)" "unprognostic (2.60e-1)" ACOX1 PALMCOX ENSG00000161533 "Acyl-CoA oxidase 1" Q15067 17 75941507-75979177 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Deafness, Disease variant, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 113.3" "Cell type enhanced" "Detected in all" "Enterocytes: 347.2;Esophageal apical cells: 493.6;Hepatocytes: 433.4;Neutrophils: 385.3;Urothelial cells: 245.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 61.8;neutrophil: 84.5" "Lineage enriched" "Detected in all" 6 "granulocytes: 84.5" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Liver - Hepatocytes, Prostate - Prostate glandular cells, Spleen - Neutrophils_2, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB021094, HPA021192, HPA021195, HPA028759" Approved Approved Nucleoli,Peroxisomes NA NA 79000 "Cluster 35: Neutrophils - Protein binding" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 19: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 3 Peroxisomes Nucleoli "CAB021094: , HPA021192: , HPA021195: , HPA028759: " "unprognostic (2.48e-3)" "unprognostic (4.80e-2)" "unprognostic (2.03e-1)" "unprognostic (6.86e-2)" "unprognostic (6.60e-3)" "unprognostic (1.86e-1)" "unprognostic (1.81e-1)" "unprognostic (2.27e-2)" "unprognostic (1.32e-1)" "unprognostic (1.11e-1)" "potential prognostic favorable (7.42e-10)" "unprognostic (1.49e-3)" "potential prognostic favorable (9.04e-5)" "unprognostic (2.49e-2)" "unprognostic (2.25e-2)" "unprognostic (2.19e-2)" "unprognostic (1.12e-1)" "unprognostic (1.84e-1)" "unprognostic (2.23e-1)" "unprognostic (2.64e-2)" "unprognostic (6.77e-2)" "unprognostic (4.28e-1)" "unprognostic (9.81e-2)" "unprognostic (1.01e-1)" "unprognostic (3.43e-3)" "unprognostic (3.09e-1)" "unprognostic (2.63e-1)" "unprognostic (6.14e-2)" "unprognostic (6.67e-2)" "unprognostic (1.32e-1)" "unprognostic (2.47e-1)" ACOX2 "BRCACOX, BRCOX, THCCox" ENSG00000168306 "Acyl-CoA oxidase 2" Q99424 3 58505136-58537283 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 165.8" "Cell type enhanced" "Detected in many" "Adipocytes: 37.0;Cardiomyocytes: 28.6;Choroid plexus epithelial cells: 34.9;Enterocytes: 38.5;Fibro-adipogenic progenitors: 29.6;Hepatocytes: 122.9;Medullary thymic epithelial cells: 38.4;Proximal tubule cells: 31.1;Sertoli cells: 26.9" "Cell type enhanced" "Detected in many" "astrocyte: 19.4;choroid plexus epithelial cell: 24.4" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 28.9" "Region enriched" "Detected in all" 5 "choroid plexus: 30.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 4.0;liver cancer: 3.4" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Fibroblasts, Skin - Sebaceous gland cells, Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA038280, HPA064845" Enhanced Approved Vesicles,Cytosol No No 17000 "Cluster 16: Liver & Kidney - Metabolism" "Cluster 36: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 93: Hepatocytes - Bile production & excretion" 2 Vesicles Cytosol "HPA038280: , HPA064845: " "unprognostic (1.92e-1)" "unprognostic (2.73e-1)" "unprognostic (2.27e-1)" "unprognostic (2.74e-3)" "unprognostic (4.70e-2)" "unprognostic (4.78e-2)" "unprognostic (2.05e-2)" "validated prognostic favorable (4.83e-8)" "validated prognostic favorable (4.19e-4)" "unprognostic (6.45e-2)" "unprognostic (2.73e-3)" "unprognostic (9.50e-3)" "potential prognostic favorable (1.52e-4)" "unprognostic (9.93e-2)" "unprognostic (5.59e-2)" "unprognostic (6.95e-2)" "unprognostic (1.11e-1)" "unprognostic (2.19e-1)" "unprognostic (5.25e-2)" "unprognostic (6.08e-2)" "unprognostic (2.89e-2)" "unprognostic (2.24e-2)" "unprognostic (2.73e-2)" "unprognostic (1.14e-2)" "unprognostic (2.24e-1)" "unprognostic (1.30e-1)" ACOX3 ENSG00000087008 "Acyl-CoA oxidase 3, pristanoyl" O15254 4 8366282-8440723 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 101.4;Esophageal apical cells: 154.4;Syncytiotrophoblasts: 151.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035840, HPA035841" Uncertain Approved Peroxisomes NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 4 Peroxisomes "HPA035840: , HPA035841: " "unprognostic (1.83e-1)" "unprognostic (2.56e-2)" "unprognostic (2.74e-1)" "unprognostic (2.40e-1)" "potential prognostic favorable (3.30e-4)" "unprognostic (3.21e-3)" "unprognostic (5.19e-2)" "unprognostic (2.78e-3)" "potential prognostic favorable (8.40e-4)" "unprognostic (5.07e-2)" "unprognostic (3.85e-3)" "unprognostic (2.33e-1)" "potential prognostic favorable (2.51e-4)" "unprognostic (1.78e-1)" "unprognostic (6.81e-2)" "unprognostic (8.52e-2)" "unprognostic (2.04e-2)" "unprognostic (9.11e-3)" "potential prognostic unfavorable (5.03e-4)" "unprognostic (1.84e-2)" "unprognostic (1.90e-1)" "unprognostic (7.99e-2)" "unprognostic (6.22e-2)" "unprognostic (1.26e-1)" "unprognostic (2.76e-2)" "unprognostic (5.45e-2)" "unprognostic (2.45e-1)" "unprognostic (1.38e-1)" "unprognostic (1.95e-1)" "unprognostic (8.09e-2)" "unprognostic (2.34e-1)" ACOXL FLJ11042 ENSG00000153093 "Acyl-CoA oxidase like" Q9NUZ1 2 110732539-111118548 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "epididymis: 6.8;lung: 8.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 753.4;Granulosa cells: 293.6;Papillary tip epithelial cells: 256.2;Plasma cells: 233.4;Prostatic club cells: 119.5;Prostatic glandular cells: 194.8;Transitional alveolar cells: 396.6;Undifferentiated spermatogonia: 125.5;Urothelial cells: 316.4" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 10.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 6.4" "Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA035392, HPA035393" Supported Nucleoli,Cytosol NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 81: Alveolar cells - Lung function" Cytosol Nucleoli "HPA035392: , HPA035393: " "potential prognostic favorable (5.97e-7)" "unprognostic (2.28e-2)" "unprognostic (2.75e-1)" "unprognostic (1.12e-1)" "unprognostic (3.71e-2)" "unprognostic (1.80e-2)" "potential prognostic favorable (1.56e-4)" "validated prognostic favorable (4.38e-4)" "validated prognostic favorable (4.57e-4)" "unprognostic (1.18e-1)" "unprognostic (3.05e-1)" "unprognostic (2.30e-1)" "unprognostic (1.49e-2)" "unprognostic (1.06e-1)" "unprognostic (3.85e-2)" "unprognostic (4.03e-2)" "unprognostic (9.55e-2)" "unprognostic (2.71e-1)" "unprognostic (2.32e-1)" "unprognostic (6.45e-2)" ACP1 "HAAP, LMW-PTP, LMWPTP" ENSG00000143727 "Acid phosphatase 1" P24666 2 264140-278283 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 1246.8;Late spermatids: 3346.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016754 Approved Approved Nucleoplasm,Cytosol NA NA 1100000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 76: Non-specific - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 5 Nucleoplasm Cytosol "HPA016754: " "unprognostic (2.89e-1)" "unprognostic (1.09e-1)" "unprognostic (2.17e-2)" "unprognostic (2.01e-1)" "unprognostic (1.71e-1)" "unprognostic (2.34e-1)" "unprognostic (3.13e-2)" "unprognostic (6.81e-2)" "unprognostic (1.26e-1)" "unprognostic (1.41e-1)" "potential prognostic favorable (2.83e-7)" "unprognostic (2.23e-1)" "unprognostic (1.77e-2)" "validated prognostic unfavorable (2.08e-6)" "validated prognostic unfavorable (9.50e-6)" "unprognostic (1.33e-2)" "unprognostic (1.58e-1)" "unprognostic (5.79e-3)" "unprognostic (3.75e-2)" "unprognostic (5.86e-2)" "unprognostic (1.24e-1)" "unprognostic (1.45e-1)" "unprognostic (5.27e-2)" "potential prognostic unfavorable (3.22e-4)" "unprognostic (1.03e-1)" "unprognostic (3.39e-1)" "unprognostic (4.44e-2)" "unprognostic (2.47e-2)" "unprognostic (1.37e-1)" "unprognostic (1.18e-1)" "unprognostic (1.83e-1)" ACP2 LAP ENSG00000134575 "Acid phosphatase 2, lysosomal" P11117 11 47239302-47248906 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 100.9;Hofbauer cells: 116.9;Kupffer cells: 139.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 69.9" "Lineage enriched" "Detected in all" 5 "monocytes: 69.9" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Prostate - Prostate glandular cells, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 17000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 70: Non-specific - Protein processing" "Cluster 44: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 29 "unprognostic (1.99e-1)" "unprognostic (1.57e-1)" "unprognostic (1.93e-1)" "unprognostic (1.25e-1)" "unprognostic (9.40e-2)" "unprognostic (2.25e-2)" "unprognostic (3.84e-3)" "unprognostic (1.25e-1)" "unprognostic (2.36e-1)" "unprognostic (7.74e-3)" "unprognostic (7.10e-3)" "unprognostic (3.16e-1)" "potential prognostic favorable (9.88e-4)" "potential prognostic unfavorable (9.12e-4)" "unprognostic (3.33e-1)" "unprognostic (2.84e-1)" "unprognostic (4.48e-3)" "unprognostic (3.62e-1)" "unprognostic (9.54e-2)" "unprognostic (4.39e-2)" "unprognostic (5.06e-1)" "unprognostic (1.24e-2)" "unprognostic (4.05e-2)" "unprognostic (1.74e-1)" "unprognostic (1.68e-3)" "unprognostic (2.78e-1)" "unprognostic (1.66e-1)" "unprognostic (1.35e-1)" "unprognostic (2.52e-2)" "unprognostic (1.62e-1)" "unprognostic (1.76e-1)" ACP3 "ACP-3, ACPP, PAP, TM-PAP" ENSG00000014257 "Acid phosphatase 3" P15309 3 132317369-132368302 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Lipid metabolism" Hydrolase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 79 "prostate: 3409.5" "Cell type enriched" "Detected in many" 90 "Prostatic glandular cells: 24144.5" "Cell type enriched" "Detected in some" 4 "central nervous system macrophage: 55.6" "Cancer enriched" "Detected in many" 268 "Prostate Adenocarcinoma (TCGA): 2890.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 139.9" "Lineage enhanced" "Detected in many" "granulocytes: 139.9" "Cancer enriched" "Detected in many" 36 "prostate cancer: 250.9" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Prostate - Prostate glandular cells, Spleen - Neutrophils_2, Stomach - Mitotic cells (Stomach)" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000071, HPA004335, HPA063916" Enhanced "Secreted to blood" Enzyme NA NA 460000 560000 "Cluster 7: Non-specific - Innate immune response" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 60: Prostate cancer - Unknown function" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 2 "CAB000071: , HPA004335: , HPA063916: " "unprognostic (7.88e-2)" "unprognostic (1.70e-1)" "unprognostic (2.87e-1)" "unprognostic (1.25e-1)" "unprognostic (1.05e-2)" "unprognostic (4.42e-2)" "unprognostic (5.45e-2)" "unprognostic (1.08e-1)" "unprognostic (3.36e-1)" "unprognostic (1.54e-1)" "unprognostic (7.46e-2)" "unprognostic (1.13e-1)" "unprognostic (3.14e-1)" "unprognostic (4.84e-2)" "unprognostic (3.99e-2)" "unprognostic (4.19e-1)" "unprognostic (8.01e-2)" "unprognostic (9.41e-2)" "unprognostic (3.23e-2)" "unprognostic (1.51e-1)" "unprognostic (1.26e-3)" "unprognostic (7.95e-2)" "unprognostic (2.17e-1)" "unprognostic (1.16e-1)" "unprognostic (1.74e-1)" "unprognostic (2.68e-1)" ACP4 ACPT ENSG00000142513 "Acid phosphatase 4" Q9BZG2 19 50790415-50795219 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" Hydrolase "Amelogenesis imperfecta, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "skin 1: 1.1;testis: 3.5" "Cell type enriched" "Detected in some" 7 "Late spermatids: 566.6" "Cell type enhanced" "Detected in some" "hippocampal CA1-3: 1.1;hippocampal CA4: 1.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 3.5" "Prostate - Prostate glandular cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA048882 Approved "Nuclear bodies,Plasma membrane,Microtubules" NA NA "Cluster 47: Testis - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 60: Prostate cancer - Unknown function" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" "Plasma membrane" "Nuclear bodies, Microtubules" "HPA048882: " "unprognostic (1.73e-1)" "unprognostic (8.70e-2)" ACP5 "HPAP, TRAcP, TRAP" ENSG00000102575 "Acid phosphatase 5, tartrate resistant" P13686 19 11574653-11579993 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 155.5" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 181.9;Esophageal suprabasal cells: 80.1;Gastric chief cells: 65.5;Hepatic stellate cells: 58.1;Hofbauer cells: 82.6;Kupffer cells: 109.7;Macrophages: 251.7;Retinal pigment epithelial cells: 149.2" "Group enriched" "Detected in some" 4 "fibroblast: 5.2;leukocyte: 9.6" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "thalamus: 27.0" "Immune cell enhanced" "Detected in many" "memory B-cell: 172.5" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in many" 7 "skin cancer: 80.1" "Adipose subcutaneous - Macrophages, Kidney - Proximal tubular cells, Liver - Sinusoid Endothelial cells, Lung - Macrophages, Prostate - Prostate glandular cells, Skeletal muscle - Macrophages" "Low region specificity" "Detected in single" "Not detected" "Not detected" "CAB002584, HPA057655, HPA059463" Enhanced Uncertain Cytosol "Intracellular and membrane" Enzyme NA NA 990000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 5: Spleen - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 69: Skin cancer - ECM organization" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 2 Cytosol "CAB002584: , HPA057655: , HPA059463: " "unprognostic (1.46e-1)" "unprognostic (9.60e-2)" "unprognostic (2.01e-1)" "unprognostic (2.74e-2)" "unprognostic (2.09e-1)" "unprognostic (3.72e-1)" "unprognostic (1.02e-1)" "unprognostic (7.54e-2)" "unprognostic (1.10e-1)" "unprognostic (1.92e-1)" "potential prognostic favorable (4.83e-5)" "unprognostic (3.81e-2)" "unprognostic (4.86e-3)" "unprognostic (1.43e-1)" "unprognostic (3.39e-1)" "unprognostic (4.21e-2)" "unprognostic (1.00e-1)" "unprognostic (9.03e-2)" "unprognostic (3.89e-2)" "unprognostic (8.38e-2)" "unprognostic (1.94e-2)" "unprognostic (1.87e-2)" "unprognostic (1.90e-2)" "unprognostic (1.38e-1)" "unprognostic (6.71e-2)" "unprognostic (3.92e-2)" "unprognostic (2.92e-1)" "unprognostic (1.41e-1)" "unprognostic (5.29e-2)" "unprognostic (2.09e-2)" "unprognostic (7.32e-2)" ACP6 "ACPL1, LPAP" ENSG00000162836 "Acid phosphatase 6, lysophosphatidic" Q9NPH0 1 147629652-147670524 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Phospholipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 90.9;Distal convoluted tubule cells: 67.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028560 Uncertain "Intracellular and membrane" Enzyme NA NA 42000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 17: Choroid plexus - Cilium" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 48: Neutrophils - Phagocytosis & degranulation" "HPA028560: " "unprognostic (1.22e-1)" "unprognostic (1.87e-1)" "unprognostic (1.45e-1)" "unprognostic (2.21e-1)" "unprognostic (1.30e-1)" "unprognostic (6.81e-2)" "unprognostic (9.21e-2)" "unprognostic (2.24e-1)" "unprognostic (1.24e-3)" "unprognostic (1.75e-2)" "potential prognostic favorable (3.71e-6)" "unprognostic (4.20e-3)" "unprognostic (1.85e-1)" "unprognostic (1.07e-2)" "unprognostic (2.70e-2)" "unprognostic (7.91e-2)" "unprognostic (2.63e-3)" "unprognostic (2.53e-1)" "unprognostic (3.85e-2)" "unprognostic (2.29e-1)" "unprognostic (2.21e-1)" "unprognostic (3.72e-1)" "unprognostic (1.42e-1)" "unprognostic (1.79e-1)" "unprognostic (8.45e-2)" "unprognostic (1.39e-1)" "unprognostic (5.48e-2)" "unprognostic (2.05e-2)" "unprognostic (1.87e-2)" "unprognostic (4.42e-1)" "unprognostic (1.17e-1)" ACP7 "FLJ16165, PAPL, PAPL1" ENSG00000183760 "Acid phosphatase 7, tartrate resistant (putative)" Q6ZNF0 19 39083913-39111493 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.1;skin 1: 5.6" "Group enriched" "Detected in some" 4 "Brain excitatory neurons: 7.0;Esophageal apical cells: 18.6;Oligodendrocytes: 11.4" "Cell type enhanced" "Detected in some" "oligodendrocyte: 12.6;upper rhombic lip: 18.8" "Group enriched" "Detected in some" 6 "Bladder Urothelial Carcinoma (TCGA): 1.9;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 1.1;Head and Neck Squamous Cell Carcinoma (TCGA): 3.7;Lung Squamous Cell Carcinoma (TCGA): 4.0;Skin Cutaneous Melanoma (TCGA): 1.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Pituitary gland - Gonadotropes, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA042613 Uncertain "Secreted - unknown location" Enzyme NA NA "Cluster 2: Non-specific - Mixed function" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 9 "HPA042613: " "unprognostic (3.26e-2)" "unprognostic (2.20e-1)" "unprognostic (1.95e-1)" "unprognostic (1.44e-1)" "unprognostic (7.26e-2)" "unprognostic (2.51e-1)" ACR ENSG00000100312 Acrosin P10323 22 50738196-50745339 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 28 "testis: 80.9" "Group enriched" "Detected in some" 30 "Early spermatids: 37.3;Late primary spermatocytes: 22.3;Late spermatids: 70.9" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 7 "choroid plexus: 5.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA048687 Enhanced "Secreted in male reproductive system" Enzyme NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 36: Choroid plexus - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 1 "HPA048687: " "unprognostic (9.28e-2)" ACRBP "CT23, OY-TES-1, SP32" ENSG00000111644 "Acrosin binding protein" Q8NEB7 12 6638075-6647433 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 20 "testis: 271.0" "Group enriched" "Detected in many" 9 "Early spermatids: 1191.4;Late primary spermatocytes: 1163.0;Late spermatids: 939.1;Platelets: 3356.0" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 5.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 12.5;intermediate monocyte: 15.8;myeloid DC: 17.7;non-classical monocyte: 31.2" "Group enriched" "Detected in many" 9 "dendritic cells: 17.7;monocytes: 31.2" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039081, HPA039082" Enhanced Approved Nucleoplasm,Vesicles,Cytosol "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 57: Testis - Spermatogenesis" "Cluster 6: Non-specific - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 47: Platelets - Hemostasis" 5 "Nucleoplasm, Vesicles" Cytosol "HPA039081: , HPA039082: " "unprognostic (4.68e-2)" "unprognostic (1.65e-1)" "unprognostic (7.09e-3)" "unprognostic (3.01e-2)" "unprognostic (7.82e-2)" "unprognostic (4.24e-1)" "unprognostic (1.89e-1)" "unprognostic (3.24e-1)" "unprognostic (2.49e-3)" "unprognostic (2.38e-3)" "unprognostic (1.03e-2)" "unprognostic (2.63e-1)" "unprognostic (2.05e-2)" "unprognostic (3.46e-2)" "unprognostic (4.58e-2)" "unprognostic (1.40e-1)" "unprognostic (9.93e-2)" "unprognostic (8.37e-2)" "unprognostic (5.95e-2)" "unprognostic (1.01e-1)" "unprognostic (2.27e-2)" "unprognostic (2.98e-1)" "unprognostic (1.08e-1)" "unprognostic (1.38e-1)" "unprognostic (9.95e-2)" "unprognostic (2.17e-1)" "unprognostic (1.01e-1)" "unprognostic (7.13e-2)" "unprognostic (1.11e-1)" ACRV1 "D11S4365, SP-10, SPACA2" ENSG00000134940 "Acrosomal vesicle protein 1" P26436 11 125671522-125680874 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 33 "testis: 110.6" "Group enriched" "Detected in some" 66 "Early spermatids: 1056.1;Late primary spermatocytes: 445.8;Late spermatids: 332.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038718, HPA038719" Enhanced Supported Acrosome "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 3 Acrosome "HPA038718: , HPA038719: " "unprognostic (2.67e-1)" "unprognostic (5.02e-2)" "potential prognostic favorable (2.66e-4)" "unprognostic (4.10e-1)" ACSBG1 "BG1, BGM, FLJ30320, hBG1, hsBG, KIAA0631, MGC14352" ENSG00000103740 "Acyl-CoA synthetase bubblegum family member 1" Q96GR2 15 78167468-78245688 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 38.5;skin 1: 13.5" "Cell type enhanced" "Detected in many" "Astrocytes: 363.2;Bergmann glia: 162.1;Cardiomyocytes: 118.5;Differentiating spermatogonia: 74.0;Erythrocyte progenitors: 66.1;Oligodendrocytes: 83.3;Oocytes: 96.7;Platelets: 73.2;Respiratory ciliated cells: 41.3" "Group enriched" "Detected in many" 9 "astrocyte: 420.1;Bergmann glia: 151.9;oligodendrocyte: 243.7" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 16.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "plasmacytoid DC: 1.0" "Lineage enriched" "Detected in single" 4 "dendritic cells: 1.0" "Cancer enhanced" "Detected in some" "Leukemia: 2.4" "Colon - Enteric glia cells, Lung - Respiratory ciliated cells, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041642, CAB045955, HPA058869" Approved Approved Vesicles NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 28: Astrocytes - Homeostasis & neuron support" Vesicles "CAB045955: , HPA041642: , HPA058869: " "unprognostic (6.61e-2)" "potential prognostic favorable (1.53e-5)" "unprognostic (2.53e-1)" "unprognostic (2.80e-2)" "unprognostic (1.09e-1)" "unprognostic (1.27e-1)" "unprognostic (1.06e-1)" "unprognostic (7.89e-2)" "unprognostic (1.19e-1)" "unprognostic (4.76e-2)" "unprognostic (1.70e-1)" ACSBG2 "BGR, DKFZp434K1635, PRTD-NY3" ENSG00000130377 "Acyl-CoA synthetase bubblegum family member 2" Q5FVE4 19 6135247-6193094 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Fatty acid metabolism, Lipid metabolism, Spermatogenesis" "Developmental protein, Ligase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 274 "testis: 120.8" "Cell type enriched" "Detected in many" 5 "Late spermatids: 3180.8" "Cell type enriched" "Detected in many" 4 "Bergmann glia: 41.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells, Kidney - Proximal tubular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043421, HPA051013" Enhanced Supported Cytosol NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 25: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" Cytosol "HPA043421: , HPA051013: " ACSF2 "ACSMW, FLJ20920" ENSG00000167107 "Acyl-CoA synthetase family member 2" Q96CM8 17 50426158-50474845 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 132.8" "Cell type enhanced" "Detected in many" "Adipocytes: 112.5;Adrenal cortex cells: 105.1;Cytotrophoblasts: 135.8;Enterocytes: 110.6;Myonuclei: 115.7;Proximal tubule cells: 467.1" "Cell type enhanced" "Detected in many" "astrocyte: 48.2;Bergmann glia: 39.0;central nervous system macrophage: 47.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate basal glandular cells, Stomach - Gastric mucous cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024693 Enhanced Uncertain Nucleoplasm,Microtubules,Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 72: Kidney - Transmembrane transport" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 88: Proximal tubular cells - Transmembrane transport" 44 "Nucleoplasm, Microtubules, Cytosol" "HPA024693: " "unprognostic (1.04e-1)" "unprognostic (1.32e-1)" "unprognostic (6.58e-2)" "unprognostic (6.68e-2)" "unprognostic (6.04e-2)" "unprognostic (4.27e-3)" "unprognostic (1.46e-1)" "unprognostic (1.12e-2)" "unprognostic (2.98e-1)" "unprognostic (1.68e-3)" "unprognostic (8.72e-2)" "unprognostic (3.83e-2)" "unprognostic (7.58e-2)" "unprognostic (1.21e-1)" "unprognostic (2.56e-1)" "unprognostic (6.58e-2)" "unprognostic (4.11e-2)" "unprognostic (4.24e-2)" "unprognostic (3.07e-1)" "unprognostic (1.92e-2)" "unprognostic (2.05e-1)" "unprognostic (5.85e-2)" "unprognostic (4.57e-2)" "unprognostic (1.13e-1)" "unprognostic (2.91e-2)" "unprognostic (2.09e-2)" "unprognostic (1.44e-1)" "unprognostic (6.59e-3)" "unprognostic (2.14e-1)" "unprognostic (2.57e-3)" "unprognostic (1.52e-1)" ACSF3 ENSG00000176715 "Acyl-CoA synthetase family member 3" Q4G176 16 89088375-89164121 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA079318 Supported Mitochondria NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 77: Intestine - Digestion" "Cluster 6: Non-specific - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 7: Non-specific - Transcription" 29 Mitochondria "HPA079318: " "unprognostic (4.58e-1)" "unprognostic (3.10e-1)" "unprognostic (1.75e-1)" "unprognostic (2.51e-2)" "unprognostic (1.54e-1)" "unprognostic (2.49e-2)" "unprognostic (1.66e-1)" "potential prognostic favorable (4.96e-4)" "unprognostic (3.32e-1)" "unprognostic (1.83e-2)" "potential prognostic favorable (7.94e-5)" "unprognostic (2.44e-1)" "unprognostic (2.96e-3)" "unprognostic (3.87e-1)" "potential prognostic favorable (1.12e-4)" "unprognostic (2.59e-1)" "unprognostic (1.99e-2)" "unprognostic (1.03e-1)" "unprognostic (3.17e-1)" "unprognostic (1.68e-1)" "unprognostic (5.89e-2)" "unprognostic (6.53e-2)" "unprognostic (9.38e-2)" "unprognostic (2.12e-2)" "unprognostic (2.82e-1)" "unprognostic (2.64e-1)" "unprognostic (1.32e-1)" "unprognostic (3.96e-2)" "unprognostic (2.01e-1)" "unprognostic (1.27e-1)" "unprognostic (6.54e-3)" ACSL1 "ACS1, FACL1, FACL2, LACS, LACS1, LACS2" ENSG00000151726 "Acyl-CoA synthetase long chain family member 1" P33121 4 184755595-184826818 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 680.0;liver: 1068.9;skeletal muscle: 697.4" "Cell type enriched" "Detected in many" 4 "Neutrophils: 13298.7" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 266.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 9 "neutrophil: 456.1" "Lineage enriched" "Detected in all" 9 "granulocytes: 456.1" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Lung - Neutrophils_2, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells, Spleen - Neutrophils_2, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011316, HPA011317, HPA011964" Enhanced Uncertain Vesicles NA NA 63000 "Cluster 4: Neutrophils - Degranulation" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 30: White matter - Myelination" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 1 Vesicles "HPA011316: , HPA011317: , HPA011964: " "unprognostic (1.52e-3)" "unprognostic (1.86e-2)" "unprognostic (1.03e-1)" "unprognostic (1.36e-1)" "unprognostic (1.00e-1)" "unprognostic (1.24e-2)" "unprognostic (2.99e-2)" "unprognostic (6.56e-2)" "unprognostic (2.94e-2)" "unprognostic (9.70e-2)" "potential prognostic favorable (2.63e-7)" "unprognostic (3.73e-3)" "unprognostic (3.70e-1)" "unprognostic (5.87e-3)" "unprognostic (1.51e-3)" "unprognostic (2.62e-1)" "potential prognostic unfavorable (5.71e-4)" "unprognostic (4.78e-1)" "unprognostic (4.23e-1)" "unprognostic (3.92e-2)" "unprognostic (6.06e-2)" "unprognostic (1.40e-1)" "unprognostic (1.81e-2)" "unprognostic (1.63e-1)" "unprognostic (6.96e-2)" "unprognostic (3.22e-1)" "unprognostic (3.92e-1)" "unprognostic (2.03e-1)" "unprognostic (5.32e-2)" "unprognostic (7.86e-3)" "unprognostic (2.34e-2)" ACSL3 "ACS3, FACL3, PRO2194" ENSG00000123983 "Acyl-CoA synthetase long chain family member 3" O95573 2 222860942-222944639 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 161.9" "Cell type enhanced" "Detected in all" "Neutrophils: 778.1;Prostatic glandular cells: 593.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Prostate glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011315, HPA071021" Approved Approved "Nucleoli,Nucleoli rim,Lipid droplets" NA NA 22000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 14: Neurons - Synaptic function" "Cluster 69: Skin cancer - ECM organization" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 22 "Nucleoli, Nucleoli rim" "Lipid droplets" "HPA011315: , HPA071021: " "unprognostic (7.25e-2)" "unprognostic (9.45e-2)" "unprognostic (8.74e-2)" "unprognostic (2.22e-2)" "unprognostic (1.91e-2)" "unprognostic (5.62e-2)" "unprognostic (2.06e-1)" "unprognostic (3.29e-3)" "unprognostic (6.97e-2)" "unprognostic (1.32e-2)" "potential prognostic favorable (2.11e-6)" "unprognostic (1.17e-2)" "unprognostic (1.28e-1)" "validated prognostic unfavorable (4.09e-5)" "validated prognostic unfavorable (9.71e-4)" "potential prognostic unfavorable (4.50e-4)" "unprognostic (1.80e-1)" "unprognostic (9.11e-2)" "unprognostic (2.23e-1)" "unprognostic (2.35e-2)" "unprognostic (9.87e-2)" "unprognostic (1.12e-1)" "unprognostic (1.43e-1)" "unprognostic (2.80e-2)" "unprognostic (2.97e-1)" "unprognostic (7.62e-2)" "unprognostic (1.23e-1)" "unprognostic (3.16e-1)" "unprognostic (1.86e-1)" "unprognostic (8.42e-2)" "unprognostic (3.07e-1)" ACSL4 "ACS4, FACL4, LACS4, MRX63, MRX68" ENSG00000068366 "Acyl-CoA synthetase long chain family member 4" O60488 X 109624244-109733403 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Alport syndrome, Deafness, Disease variant, Elliptocytosis, Hereditary hemolytic anemia, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 427.0;Distal convoluted tubule cells: 905.2;Epicardial cells: 459.4;Mast cells: 1266.9;Neutrophils: 1707.8;Sertoli cells: 452.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000286, HPA005552" Supported Approved "Golgi apparatus,Mitochondria" NA NA 13000 "Cluster 28: Neutrophils - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 27: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 24: Neutrophils - Innate immunity signal integration" 11 "Golgi apparatus" Mitochondria "HPA000286: , HPA005552: " "unprognostic (1.99e-1)" "unprognostic (4.14e-2)" "unprognostic (2.74e-1)" "unprognostic (7.53e-3)" "unprognostic (8.87e-2)" "unprognostic (3.24e-3)" "unprognostic (3.02e-1)" "unprognostic (4.42e-2)" "unprognostic (6.84e-2)" "unprognostic (3.93e-2)" "potential prognostic favorable (6.78e-4)" "unprognostic (1.30e-1)" "unprognostic (8.51e-3)" "unprognostic (3.13e-2)" "unprognostic (4.98e-2)" "unprognostic (2.22e-3)" "unprognostic (3.97e-2)" "unprognostic (5.62e-2)" "unprognostic (1.38e-1)" "unprognostic (3.65e-1)" "unprognostic (1.24e-2)" "unprognostic (7.64e-2)" "unprognostic (8.32e-2)" "unprognostic (1.27e-1)" "unprognostic (2.51e-1)" "unprognostic (9.81e-2)" "unprognostic (4.71e-2)" "unprognostic (1.23e-1)" "unprognostic (1.73e-1)" "unprognostic (6.23e-3)" "unprognostic (3.83e-1)" ACSL5 "ACS2, ACS5, FACL5" ENSG00000197142 "Acyl-CoA synthetase long chain family member 5" Q9ULC5 10 112374116-112428379 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 211.6;intestine: 405.8;liver: 159.5" "Cell type enhanced" "Detected in many" "Colonocytes: 206.7;Endometrial ciliated cells: 185.0;Endometrial glandular cells: 606.6;Endometrial luminal cells: 265.4;Enterocytes: 943.9;Epididymal principal cells: 280.1;Urothelial cells: 449.6" "Cell type enhanced" "Detected in all" "endothelial cell: 116.0;leukocyte: 49.9" "Cancer enhanced" "Detected in all" "Rectum Adenocarcinoma (TCGA): 159.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Bile duct cancer: 97.2;colorectal cancer: 99.3" "Breast - Endothelial cells, Heart muscle - Endothelial cells, Pituitary gland - Endothelial cells, Skeletal muscle - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007162, CAB035986, CAB062546" Enhanced Supported Nucleoplasm,Mitochondria NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 77: Intestine - Digestion" "Cluster 47: Endothelial cells - Vasculature" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 51: Secretory epithelial cells - Mixed function" 9 Mitochondria Nucleoplasm "CAB035986: , CAB062546: , HPA007162: " "unprognostic (3.12e-3)" "unprognostic (1.46e-2)" "unprognostic (6.23e-2)" "unprognostic (8.94e-2)" "unprognostic (3.45e-1)" "unprognostic (8.33e-3)" "unprognostic (1.32e-1)" "unprognostic (6.12e-2)" "unprognostic (2.07e-2)" "unprognostic (8.68e-2)" "unprognostic (4.45e-3)" "unprognostic (1.91e-2)" "unprognostic (2.64e-1)" "unprognostic (8.36e-2)" "unprognostic (1.78e-1)" "unprognostic (3.83e-2)" "unprognostic (2.96e-1)" "unprognostic (1.73e-2)" "unprognostic (3.11e-2)" "unprognostic (4.15e-2)" "unprognostic (6.14e-2)" "potential prognostic unfavorable (5.84e-4)" "unprognostic (2.65e-2)" "unprognostic (7.27e-2)" "unprognostic (1.09e-2)" "unprognostic (2.33e-1)" "unprognostic (9.64e-2)" "unprognostic (1.37e-1)" "unprognostic (6.90e-2)" "unprognostic (1.37e-2)" "unprognostic (4.99e-2)" ACSL6 "ACS2, FACL6, KIAA0837, LACS2, LACS5" ENSG00000164398 "Acyl-CoA synthetase long chain family member 6" Q9UKU0 5 131949973-132012243 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 21.4;brain: 29.5;retina: 42.4;testis: 19.3" "Cell type enhanced" "Detected in some" "Astrocytes: 4.2;Bergmann glia: 3.5;Early spermatids: 1.5;Late primary spermatocytes: 5.3;Retinal amacrine cells: 1.4;Rod photoreceptor cells: 1.6" "Cell type enhanced" "Detected in some" "astrocyte: 4.6" "Group enriched" "Detected in some" 4 "Colon Adenocarcinoma (TCGA): 4.6;Glioblastoma Multiforme (TCGA): 6.9;Liver Hepatocellular Carcinoma (TCGA): 3.0;Rectum Adenocarcinoma (TCGA): 6.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory CD8 T-cell: 1.6" "Lineage enriched" "Detected in single" 5 "T-cells: 1.6" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Heart muscle - Cardiomyocytes, Kidney - Ascending Loop of Henle cells, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040470 Enhanced Approved Vesicles,Cytosol NA NA "Cluster 11: T-cells - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 47: Leukemia - Hemostasis" "Cluster 28: Astrocytes - Homeostasis & neuron support" Vesicles Cytosol "HPA040470: " "unprognostic (1.86e-2)" "unprognostic (1.45e-1)" "unprognostic (1.75e-2)" "unprognostic (7.41e-2)" "unprognostic (3.53e-1)" "unprognostic (8.11e-2)" "unprognostic (1.23e-2)" "unprognostic (1.43e-2)" "potential prognostic unfavorable (2.34e-4)" "unprognostic (5.50e-3)" "unprognostic (1.71e-1)" "unprognostic (1.29e-1)" ACSM1 "BUCS1, MACS1" ENSG00000166743 "Acyl-CoA synthetase medium chain family member 1" Q08AH1 16 20623235-20698890 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 21 "breast: 202.0" "Group enriched" "Detected in many" 6 "Epicardial cells: 432.1;Fibroblasts: 172.0" "Low cell type specificity" "Detected in some" "Group enriched" "Detected in many" 7 "Liver Hepatocellular Carcinoma (TCGA): 34.3;Prostate Adenocarcinoma (TCGA): 85.9" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "eosinophil: 1.3;memory B-cell: 1.7" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "prostate cancer: 3.0" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Prostate - Prostate glandular cells, Testis - Late spermatids" "Not detected" "Not detected" HPA046291 Uncertain NA NA "Cluster 34: B-cells - Unknown function" "Cluster 55: Breast - Lactation" "Cluster 47: Leukemia - Hemostasis" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 4 "HPA046291: " "unprognostic (1.98e-1)" "unprognostic (1.40e-1)" "unprognostic (6.19e-2)" "unprognostic (6.09e-2)" "unprognostic (1.93e-3)" "unprognostic (2.39e-2)" "potential prognostic favorable (2.91e-5)" "unprognostic (3.67e-2)" "unprognostic (6.47e-3)" "unprognostic (3.47e-1)" "unprognostic (2.26e-3)" "unprognostic (4.50e-1)" ACSM2A "A-923A4.1, ACSM2, MGC150530" ENSG00000183747 "Acyl-CoA synthetase medium chain family member 2A" Q08AH3 16 20451461-20487669 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 1198 "kidney: 258.7;liver: 350.0" "Group enriched" "Detected in some" 47 "Hepatocytes: 831.9;Proximal tubule cells: 2397.3" "Not detected" "Not detected" "Group enriched" "Detected in some" 508 "Kidney Renal Clear Cell Carcinoma (TCGA): 91.0;Kidney Renal Papillary Cell Carcinoma (TCGA): 150.0;Liver Hepatocellular Carcinoma (TCGA): 96.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "liver cancer: 1.2" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" HPA057699 Supported NA NA 87000 "Cluster 16: Liver & Kidney - Metabolism" "Cluster 18: Liver cancer - Metabolism" "Cluster 88: Proximal tubular cells - Transmembrane transport" "HPA057699: " "potential prognostic favorable (6.71e-6)" "unprognostic (8.14e-3)" "potential prognostic favorable (1.96e-5)" "validated prognostic favorable (1.61e-4)" "validated prognostic favorable (4.77e-7)" "unprognostic (2.09e-2)" ACSM2B "ACSM2, HXMA, HYST1046" ENSG00000066813 "Acyl-CoA synthetase medium chain family member 2B" Q68CK6 16 20536226-20576427 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 338 "kidney: 386.3;liver: 509.8" "Group enriched" "Detected in some" 64 "Hepatocytes: 1415.5;Proximal tubule cells: 2116.1" "Not detected" "Not detected" "Group enriched" "Detected in many" 77 "Kidney Renal Clear Cell Carcinoma (TCGA): 135.2;Kidney Renal Papillary Cell Carcinoma (TCGA): 85.4;Liver Hepatocellular Carcinoma (TCGA): 216.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" HPA057699 Supported NA NA "Cluster 16: Liver & Kidney - Metabolism" "Cluster 15: Non-specific - Transcription" "Cluster 18: Liver cancer - Metabolism" "Cluster 88: Proximal tubular cells - Transmembrane transport" 1 "HPA057699: " "potential prognostic unfavorable (4.32e-4)" "unprognostic (9.47e-2)" "unprognostic (8.61e-2)" "unprognostic (1.23e-1)" "potential prognostic favorable (8.87e-5)" "unprognostic (2.19e-3)" "unprognostic (9.09e-3)" "validated prognostic favorable (1.50e-4)" "validated prognostic favorable (7.01e-7)" "unprognostic (4.18e-2)" "unprognostic (1.55e-1)" "unprognostic (1.88e-2)" "unprognostic (3.93e-2)" "unprognostic (4.22e-2)" "unprognostic (1.27e-1)" "unprognostic (1.29e-2)" "unprognostic (3.13e-1)" ACSM3 "SA, SAH" ENSG00000005187 "Acyl-CoA synthetase medium chain family member 3" Q53FZ2 16 20610243-20797581 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 79.3;liver: 166.3;ovary: 72.9" "Cell type enhanced" "Detected in many" "Granulosa cells: 1620.4;Megakaryocyte-Erythroid progenitors: 244.7;Mesothelial cells: 222.7;Ovarian stromal cells: 976.6;Proximal tubule cells: 318.7;Sertoli cells: 564.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 23.5" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 29.9" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Liver - Hepatocytes, Liver - Hepatocytes, Skin - Sebaceous gland cells, Stomach - Chief cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA041013 Uncertain NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 6: Non-specific - Immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 94: Gonadal somatic cells - Mixed function" 3 "HPA041013: " "unprognostic (1.50e-1)" "unprognostic (9.90e-2)" "unprognostic (2.39e-1)" "unprognostic (8.63e-3)" "unprognostic (1.75e-1)" "unprognostic (5.12e-3)" "unprognostic (3.73e-2)" "unprognostic (3.70e-2)" "potential prognostic favorable (1.36e-6)" "unprognostic (2.66e-1)" "unprognostic (6.69e-2)" "unprognostic (3.83e-3)" "unprognostic (8.15e-2)" "unprognostic (5.20e-2)" "unprognostic (3.20e-1)" "unprognostic (2.27e-2)" "unprognostic (3.71e-1)" "unprognostic (1.62e-2)" "unprognostic (1.96e-1)" "unprognostic (1.56e-2)" "unprognostic (5.45e-2)" "unprognostic (3.45e-2)" "unprognostic (2.09e-2)" "unprognostic (2.71e-2)" "unprognostic (7.03e-3)" "unprognostic (1.06e-1)" "unprognostic (7.12e-2)" "unprognostic (3.97e-2)" "unprognostic (1.86e-1)" ACSM4 ENSG00000215009 "Acyl-CoA synthetase medium chain family member 4" P0C7M7 12 7304072-7328719 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Epicardial cells: 2.3;Macrophages: 5.5;Neutrophils: 2.4;Pericytes: 2.1;Retinal amacrine cells: 6.2;Retinal bipolar cells: 2.3;Retinal ganglion cells: 19.3;Undifferentiated spermatogonia: 5.2" "Cell type enhanced" "Detected in many" "lower rhombic lip: 9.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Neuroblastoma: 1.2" "Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA049895 Uncertain NA NA "Cluster 24: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "HPA049895: " ACSM5 FLJ20581 ENSG00000183549 "Acyl-CoA synthetase medium chain family member 5" Q6NUN0 16 20409534-20441336 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "liver: 258.6" "Cell type enriched" "Detected in some" 4 "Hepatocytes: 307.9" "Cell type enriched" "Detected in some" 6 "central nervous system macrophage: 91.4" "Group enriched" "Detected in many" 5 "Kidney Renal Clear Cell Carcinoma (TCGA): 29.5;Kidney Renal Papillary Cell Carcinoma (TCGA): 26.1;Liver Hepatocellular Carcinoma (TCGA): 41.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney cancer: 4.0" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Macrophages, Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA041435 Uncertain Uncertain Vesicles NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 93: Hepatocytes - Bile production & excretion" Vesicles "HPA041435: " "unprognostic (2.55e-2)" "unprognostic (1.12e-2)" "unprognostic (1.46e-1)" "unprognostic (1.57e-2)" "potential prognostic favorable (3.88e-6)" "unprognostic (6.34e-2)" "unprognostic (4.95e-3)" "unprognostic (9.03e-3)" "potential prognostic favorable (1.82e-4)" "unprognostic (4.72e-2)" "unprognostic (7.13e-3)" "unprognostic (5.01e-2)" "unprognostic (1.36e-1)" ACSM6 "bA310E22.3, C10orf129" ENSG00000173124 "Acyl-CoA synthetase medium chain family member 6" Q6P461 10 95194200-95228929 "Enzymes, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 2.9;pancreas: 2.9;skin 1: 1.5;stomach 1: 1.5" "Cell type enhanced" "Detected in many" "Adipocytes: 42.5;Cardiomyocytes: 28.1;Epicardial cells: 188.8;Retinal bipolar cells: 37.3;Rod photoreceptor cells: 76.8;Urothelial cells: 98.2" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in single" 6 "Bladder Urothelial Carcinoma (TCGA): 1.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Sebaceous gland cells, Testis - Early spermatids, Testis - Late spermatids" HPA044593 Uncertain NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 33: Neurons - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 69: Urothelial cells - Basic cellular functions" "HPA044593: " "unprognostic (6.04e-1)" ACSS1 "ACAS2L, AceCS2L, dJ568C11.3, MGC33843" ENSG00000154930 "Acyl-CoA synthetase short chain family member 1" Q9NUB1 20 25006230-25058980 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 170.2" "Cell type enhanced" "Detected in many" "Astrocytes: 348.8;Bergmann glia: 243.6;Choroid plexus epithelial cells: 267.4;Cytotrophoblasts: 490.1;Sertoli cells: 196.9;Syncytiotrophoblasts: 574.1" "Cell type enhanced" "Detected in many" "astrocyte: 315.6;Bergmann glia: 224.1;choroid plexus epithelial cell: 216.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Prostate - Prostate glandular cells, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041014, HPA043228" Enhanced NA NA "Cluster 32: Basophils - Transcription" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 2 "HPA041014: , HPA043228: " "unprognostic (2.38e-3)" "unprognostic (2.87e-1)" "unprognostic (4.42e-2)" "unprognostic (8.00e-3)" "unprognostic (6.62e-2)" "unprognostic (9.45e-3)" "unprognostic (3.75e-1)" "unprognostic (1.12e-1)" "unprognostic (2.36e-2)" "unprognostic (5.51e-2)" "unprognostic (3.47e-3)" "potential prognostic favorable (6.16e-5)" "unprognostic (9.23e-3)" "unprognostic (1.73e-3)" "unprognostic (1.34e-2)" "potential prognostic favorable (3.01e-4)" "unprognostic (2.84e-2)" "unprognostic (1.66e-1)" "unprognostic (2.81e-2)" "unprognostic (1.20e-1)" "unprognostic (6.22e-2)" "unprognostic (1.85e-1)" "unprognostic (2.56e-2)" "unprognostic (1.97e-1)" "unprognostic (1.48e-1)" "unprognostic (1.58e-1)" "unprognostic (9.58e-3)" "unprognostic (2.13e-2)" "unprognostic (1.16e-1)" "unprognostic (4.33e-1)" "unprognostic (1.82e-1)" ACSS2 "ACAS2, AceCS, ACS, ACSA, dJ1161H23.1" ENSG00000131069 "Acyl-CoA synthetase short chain family member 2" Q9NR19 20 34872146-34927962 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Transcription, Transcription regulation" "Activator, Ligase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 109.9" "Cell type enhanced" "Detected in many" "Adipocytes: 425.7;Breast lactating cells: 357.2;Cardiomyocytes: 521.6;Colonocytes: 244.1;Goblet cells: 263.3;Myonuclei: 359.2" "Cell type enhanced" "Detected in all" "oligodendrocyte: 138.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 34.5" "Group enriched" "Detected in many" 5 "dendritic cells: 22.6;granulocytes: 34.5;monocytes: 21.8" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Alveolar cells type 2, Skin - Sebaceous gland cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004141, HPA004183, HPA070826" Approved Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA 58000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 89: Adipocytes - Lipid metabolism" Nucleoplasm "Vesicles, Plasma membrane, Cytosol" "HPA004141: , HPA004183: , HPA070826: " "unprognostic (1.74e-3)" "unprognostic (1.77e-1)" "unprognostic (2.90e-3)" "unprognostic (9.24e-3)" "unprognostic (2.80e-2)" "unprognostic (2.44e-1)" "unprognostic (3.43e-2)" "unprognostic (3.02e-2)" "unprognostic (1.08e-1)" "unprognostic (2.49e-2)" "potential prognostic favorable (3.14e-6)" "unprognostic (7.73e-3)" "unprognostic (9.49e-3)" "unprognostic (9.16e-2)" "unprognostic (2.18e-2)" "unprognostic (1.46e-1)" "unprognostic (1.49e-1)" "unprognostic (8.17e-2)" "unprognostic (1.26e-3)" "unprognostic (1.22e-1)" "unprognostic (3.49e-1)" "unprognostic (1.84e-1)" "unprognostic (1.07e-1)" "unprognostic (3.62e-2)" "unprognostic (2.61e-2)" "unprognostic (5.96e-2)" "unprognostic (1.08e-1)" "unprognostic (1.39e-1)" "unprognostic (3.16e-1)" "unprognostic (7.47e-3)" "unprognostic (2.05e-1)" ACSS3 FLJ21963 ENSG00000111058 "Acyl-CoA synthetase short chain family member 3" Q9H6R3 12 80936414-81261210 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 37.4" "Cell type enhanced" "Detected in many" "Adipocytes: 467.9;Adrenal cortex cells: 204.9;Astrocytes: 266.2;Bergmann glia: 212.0;Cardiomyocytes: 303.7;Ependymal cells: 244.9;Myonuclei: 270.3;Pituitary stem cells: 239.1" "Group enriched" "Detected in many" 6 "astrocyte: 268.8;Bergmann glia: 226.0;choroid plexus epithelial cell: 143.4;ependymal cell: 259.9;fibroblast: 278.4;pericyte: 312.5;vascular associated smooth muscle cell: 99.4" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 51.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 15 "basophil: 7.1;neutrophil: 2.2" "Lineage enriched" "Detected in single" 71 "granulocytes: 7.1" "Cancer enhanced" "Detected in many" "liver cancer: 10.6" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Prostate - Fibroblasts, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039353, HPA047956, HPA061517" Approved Supported Mitochondria NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 89: Adipocytes - Lipid metabolism" 2 Mitochondria "HPA039353: , HPA047956: , HPA061517: " "unprognostic (1.09e-1)" "unprognostic (6.54e-2)" "unprognostic (2.82e-2)" "unprognostic (6.83e-3)" "unprognostic (2.81e-2)" "potential prognostic unfavorable (4.61e-6)" "unprognostic (3.00e-3)" "validated prognostic favorable (3.37e-10)" "validated prognostic favorable (2.87e-6)" "unprognostic (1.70e-3)" "unprognostic (2.05e-1)" "unprognostic (2.23e-1)" "unprognostic (1.81e-3)" "unprognostic (1.15e-1)" "unprognostic (4.10e-3)" "unprognostic (2.50e-3)" "unprognostic (1.02e-2)" "unprognostic (1.80e-2)" "unprognostic (3.39e-2)" "unprognostic (7.22e-2)" "unprognostic (6.80e-2)" "unprognostic (2.12e-1)" "unprognostic (1.23e-1)" "unprognostic (1.55e-1)" "unprognostic (1.17e-3)" "unprognostic (1.65e-1)" "unprognostic (1.36e-1)" "unprognostic (3.48e-2)" ACTA1 "ACTA, NEM3" ENSG00000143632 "Actin alpha 1, skeletal muscle" P68133 1 229430365-229434104 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Muscle protein" "Disease variant, Nemaline myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "skeletal muscle: 123974.2" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 88.8;Fibro-adipogenic progenitors: 121.3;Myonuclei: 1143.9;Myosatellite cells: 137.4;Smooth muscle cells: 278.1;Thymic myoid cells: 379.3" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in many" 4 "Head and Neck Squamous Cell Carcinoma (TCGA): 203.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "breast cancer: 3.0;Sarcoma: 2.8" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Skin - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB000045, HPA041264, HPA041271" Enhanced NA NA 3500000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 34: Testis cancer - Unknown function" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 45 "CAB000045: , HPA041264: , HPA041271: " "unprognostic (1.10e-2)" "unprognostic (8.79e-2)" "unprognostic (2.05e-1)" "unprognostic (4.14e-3)" "unprognostic (7.75e-3)" "unprognostic (1.47e-3)" "unprognostic (1.17e-1)" "unprognostic (3.44e-2)" "unprognostic (2.60e-1)" "unprognostic (3.02e-2)" ACTA2 ACTSA ENSG00000107796 "Actin alpha 2, smooth muscle" P62736 10 88935074-88991339 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Muscle protein" "Aortic aneurysm, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 10509.9;smooth muscle: 7564.0" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 4004.9;Decidual stromal cells: 5619.2;Hepatic stellate cells: 7861.9;Pericytes: 1958.2;Peritubular myoid cells: 4824.3;Salivary myoepithelial cells: 1700.5;Smooth muscle cells: 7700.3;Vascular smooth muscle cells: 5257.0" "Cell type enriched" "Detected in many" 23 "vascular associated smooth muscle cell: 2247.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 58.8" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Bone cancer: 252.0;testis cancer: 273.4" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Breast - Breast myoepithelial cells, Colon - Smooth muscle cells, Heart muscle - Smooth muscle cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Smooth muscle cells, Minor Salivary Gland - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Skin - Smooth muscle cells, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "midbrain: 121.0" "CAB000002, CAB003761, CAB013531, HPA041264, HPA041271" Enhanced Approved "Actin filaments" NA NA 3100000000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 56 "Actin filaments" "CAB000002: , CAB003761: , CAB013531: , HPA041264: , HPA041271: " "unprognostic (4.20e-3)" "unprognostic (1.10e-1)" "unprognostic (1.66e-1)" "unprognostic (4.14e-1)" "unprognostic (1.20e-2)" "unprognostic (4.55e-2)" "unprognostic (3.01e-2)" "unprognostic (1.05e-1)" "unprognostic (1.51e-1)" "unprognostic (2.77e-1)" "unprognostic (6.71e-3)" "unprognostic (2.78e-2)" "potential prognostic unfavorable (1.77e-5)" "unprognostic (1.57e-2)" "unprognostic (2.80e-1)" "unprognostic (2.45e-1)" "unprognostic (2.66e-2)" "unprognostic (2.47e-3)" "unprognostic (2.01e-2)" "unprognostic (3.26e-2)" "unprognostic (2.20e-2)" "unprognostic (8.62e-2)" "unprognostic (6.91e-3)" "unprognostic (5.06e-2)" "unprognostic (3.69e-2)" "unprognostic (4.61e-2)" "potential prognostic unfavorable (3.93e-4)" "unprognostic (5.89e-3)" "unprognostic (1.30e-1)" "unprognostic (5.75e-2)" "unprognostic (1.35e-1)" ACTB ENSG00000075624 "Actin beta" P60709 7 5526409-5563902 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Deafness, Disease variant, Dystonia, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Decidual stromal cells: 10863.8;Esophageal apical cells: 15922.3;Extravillous trophoblasts: 16961.8;Hofbauer cells: 15051.8;Megakaryocytes: 22056.0;Neutrophils: 11008.5;Platelets: 18691.1" "Cell type enhanced" "Detected in all" "vascular associated smooth muscle cell: 2209.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002621, HPA041264, HPA041271" Supported NA NA 7900000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 27: Non-specific - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 47: Platelets - Hemostasis" 444 "CAB002621: , HPA041264: , HPA041271: " "unprognostic (3.08e-2)" "unprognostic (3.49e-1)" "unprognostic (3.95e-1)" "unprognostic (2.20e-2)" "unprognostic (1.82e-1)" "unprognostic (1.87e-1)" "unprognostic (6.46e-2)" "unprognostic (1.36e-2)" "unprognostic (3.66e-3)" "unprognostic (2.23e-2)" "potential prognostic unfavorable (8.22e-5)" "unprognostic (6.86e-2)" "unprognostic (2.98e-2)" "potential prognostic unfavorable (3.61e-4)" "unprognostic (4.01e-3)" "validated prognostic unfavorable (7.74e-4)" "validated prognostic unfavorable (4.83e-6)" "unprognostic (6.78e-2)" "unprognostic (2.52e-2)" "unprognostic (7.45e-2)" "unprognostic (1.78e-1)" "unprognostic (1.30e-2)" "unprognostic (1.78e-1)" "unprognostic (2.23e-1)" "unprognostic (3.60e-2)" "unprognostic (1.05e-1)" "unprognostic (2.55e-1)" "unprognostic (1.92e-2)" "unprognostic (8.77e-2)" "unprognostic (1.17e-1)" "unprognostic (4.35e-2)" ACTBL2 DKFZp686D0972 ENSG00000169067 "Actin beta like 2" Q562R1 5 57480018-57482811 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Adipocytes: 1.6;Breast myoepithelial cells: 2.6;Early spermatids: 4.3;Endometrial secretory cells: 1.3;Late spermatids: 1.2;Respiratory deuterosomal cells: 1.0;Submucosal glandular cells: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "thyroid cancer: 5.0" "Minor Salivary Gland - Minor salivary glandular cells, Skin - Inner root sheath cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041264, HPA041271" Uncertain NA NA 1100000000 "Cluster 61: BICR 18 - Protein kinases" "Cluster 89: Adipocytes - Lipid metabolism" 38 "HPA041264: , HPA041271: " "unprognostic (5.54e-2)" ACTC1 "ACTC, CMD1R" ENSG00000159251 "Actin alpha cardiac muscle 1" P68032 15 34790230-34795549 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Muscle protein" "Atrial septal defect, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 16 "heart muscle: 10840.1" "Group enriched" "Detected in some" 8 "Cardiomyocytes: 412.2;Smooth muscle cells: 644.4;Thymic myoid cells: 552.0" "Cell type enhanced" "Detected in some" "vascular associated smooth muscle cell: 8.5" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 58.3;Head and Neck Squamous Cell Carcinoma (TCGA): 110.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 9 "Sarcoma: 254.4" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Skin - Smooth muscle cells, Spleen - Smooth muscle cells, Thyroid gland - Smooth muscle cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB037330, HPA041264, HPA041271" Enhanced NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 62: Smooth muscle cells - Muscle contraction" 107 "CAB037330: , HPA041264: , HPA041271: " "unprognostic (1.37e-2)" "unprognostic (1.60e-1)" "unprognostic (2.43e-2)" "unprognostic (1.73e-1)" "unprognostic (5.59e-2)" "unprognostic (9.10e-2)" "potential prognostic unfavorable (2.28e-5)" "unprognostic (1.79e-2)" "unprognostic (2.55e-3)" "unprognostic (4.49e-2)" "potential prognostic unfavorable (2.33e-6)" "unprognostic (1.15e-1)" "unprognostic (1.31e-2)" "unprognostic (2.76e-3)" "unprognostic (1.28e-2)" "unprognostic (2.06e-1)" "unprognostic (9.55e-2)" "unprognostic (1.36e-1)" "unprognostic (6.78e-3)" "unprognostic (4.27e-1)" ACTG1 "ACTG, DFNA20, DFNA26" ENSG00000184009 "Actin gamma 1" P63261 17 81509413-81523847 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Deafness, Disease variant, Intellectual disability, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 15148.8;Esophageal suprabasal cells: 7218.0;Megakaryocytes: 5705.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041264, HPA041271" Approved NA NA 7600000000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 54: Non-specific - Ribosome" "Cluster 27: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 47: Platelets - Hemostasis" 236 "HPA041264: , HPA041271: " "unprognostic (5.11e-3)" "unprognostic (1.27e-1)" "unprognostic (1.44e-1)" "potential prognostic favorable (9.19e-5)" "potential prognostic favorable (4.95e-4)" "unprognostic (2.06e-1)" "unprognostic (1.20e-1)" "unprognostic (1.16e-1)" "unprognostic (3.11e-2)" "unprognostic (3.66e-2)" "unprognostic (6.13e-3)" "unprognostic (5.87e-3)" "unprognostic (9.26e-2)" "validated prognostic unfavorable (4.04e-4)" "validated prognostic unfavorable (1.88e-4)" "unprognostic (1.98e-3)" "unprognostic (2.76e-3)" "unprognostic (4.93e-3)" "unprognostic (1.90e-1)" "unprognostic (1.48e-1)" "unprognostic (1.75e-1)" "unprognostic (7.18e-3)" "unprognostic (1.73e-1)" "unprognostic (1.90e-1)" "unprognostic (3.91e-2)" "unprognostic (6.49e-2)" "unprognostic (1.19e-2)" "unprognostic (9.73e-2)" "unprognostic (1.16e-1)" "unprognostic (3.32e-2)" "unprognostic (7.48e-2)" ACTG2 "ACTA3, ACTL3, ACTSG" ENSG00000163017 "Actin gamma 2, smooth muscle" P63267 2 73892314-73919865 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Hydrolase, Muscle protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 8437.2;seminal vesicle: 5865.9;smooth muscle: 8032.7" "Group enriched" "Detected in many" 5 "Breast myoepithelial cells: 2393.0;Smooth muscle cells: 5914.1" "Cell type enriched" "Detected in single" 146 "vascular associated smooth muscle cell: 117.5" "Group enriched" "Detected in all" 4 "Bladder Urothelial Carcinoma (TCGA): 377.0;Prostate Adenocarcinoma (TCGA): 991.8;Stomach Adenocarcinoma (TCGA): 1103.9" "Region enhanced" "Detected in some" "cerebral cortex: 7.8" "Immune cell enriched" "Detected in single" 11 "T-reg: 8.6" "Lineage enriched" "Detected in single" 17 "T-cells: 8.6" "Cancer enhanced" "Detected in many" "Brain cancer: 108.5;breast cancer: 83.5;Rhabdoid: 87.8" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Adrenal gland - Smooth muscle cells, Colon - Smooth muscle cells, Heart muscle - Smooth muscle cells, Lung - Smooth muscle cells, Minor Salivary Gland - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Skin - Smooth muscle cells, Spleen - Smooth muscle cells, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 4 "midbrain: 15.6;spinal cord: 6.2" "HPA041264, HPA041271" Supported NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 4 "HPA041264: , HPA041271: " "potential prognostic favorable (7.14e-4)" "unprognostic (9.09e-3)" "unprognostic (1.74e-1)" "unprognostic (1.10e-1)" "unprognostic (7.16e-2)" "unprognostic (9.24e-2)" "unprognostic (8.25e-3)" "unprognostic (1.40e-1)" "unprognostic (1.81e-1)" "unprognostic (6.27e-2)" "unprognostic (2.05e-2)" "unprognostic (1.27e-3)" "potential prognostic unfavorable (1.87e-6)" "unprognostic (2.62e-1)" "unprognostic (1.49e-3)" "unprognostic (1.53e-1)" "unprognostic (2.18e-1)" "unprognostic (4.06e-3)" "unprognostic (2.50e-2)" "unprognostic (1.85e-1)" "unprognostic (4.00e-2)" "unprognostic (8.64e-2)" "unprognostic (8.33e-2)" "unprognostic (6.32e-2)" "unprognostic (1.12e-2)" "unprognostic (4.41e-2)" "unprognostic (7.65e-2)" "unprognostic (6.58e-3)" "unprognostic (1.61e-1)" "unprognostic (3.49e-2)" "unprognostic (2.05e-3)" ACTL10 C20orf134 ENSG00000288649 "Actin like 10" Q5JWF8 20 33666943-33668525 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 16 "testis: 54.9" "Cell type enhanced" "Detected in many" "Early spermatids: 410.2;Late primary spermatocytes: 197.3;Late spermatids: 855.5" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 6.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA066750 Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 79: Testis - Spermatogenesis" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" "Vesicles, Plasma membrane" Nucleoplasm "HPA066750: " "unprognostic (4.71e-2)" "unprognostic (6.31e-2)" "unprognostic (1.49e-1)" "unprognostic (3.03e-2)" "unprognostic (2.95e-3)" "unprognostic (6.89e-2)" "unprognostic (1.35e-1)" "unprognostic (9.97e-2)" ACTL6A "Actl6, Arp4, BAF53A, INO80K, SMARCN1" ENSG00000136518 "Actin like 6A" O96019 3 179562886-179588407 "Disease related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Growth regulation, Neurogenesis, Transcription, Transcription regulation" "Activator, Chromatin regulator" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 191.9;Late primary spermatocytes: 326.6;Oocytes: 308.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012188, HPA018671, HPA063149" Supported Enhanced Nucleoplasm,Cytosol NA NA 11000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 39: Testis - Nuclear processes" "Cluster 30: White matter - Myelination" "Cluster 63: Non-specific - Protein processing" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 123 Nucleoplasm Cytosol "CAB012188: , HPA018671: , HPA063149: " "unprognostic (8.44e-2)" "unprognostic (2.89e-2)" "unprognostic (1.00e-3)" "unprognostic (1.90e-1)" "unprognostic (2.36e-1)" "unprognostic (3.26e-2)" "unprognostic (3.04e-2)" "unprognostic (7.11e-2)" "unprognostic (6.33e-3)" "unprognostic (3.86e-3)" "unprognostic (1.23e-3)" "unprognostic (1.94e-1)" "unprognostic (3.04e-2)" "validated prognostic unfavorable (1.12e-4)" "validated prognostic unfavorable (8.97e-5)" "validated prognostic unfavorable (2.15e-4)" "validated prognostic unfavorable (8.83e-4)" "unprognostic (5.60e-3)" "unprognostic (1.13e-2)" "unprognostic (1.98e-1)" "unprognostic (1.88e-1)" "potential prognostic unfavorable (1.53e-4)" "unprognostic (2.39e-2)" "unprognostic (1.40e-2)" "unprognostic (5.09e-3)" "unprognostic (2.60e-1)" "unprognostic (1.90e-2)" "unprognostic (1.65e-1)" "unprognostic (2.74e-1)" "unprognostic (1.03e-1)" "unprognostic (2.39e-1)" ACTL6B "ACTL6, BAF53B, SMARCN2" ENSG00000077080 "Actin like 6B" O94805 7 100643097-100656448 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" "Chromatin regulator" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 51.2;pituitary gland: 14.6" "Group enriched" "Detected in some" 4 "Adrenal medulla cells: 31.9;Brain excitatory neurons: 39.0;Brain inhibitory neurons: 36.2;Cone photoreceptor cells: 18.6;Corticotrophs: 29.5;Gonadotrophs: 37.7;Lactotrophs: 23.9;Other brain neurons: 26.2;Pancreatic islet cells: 17.5;Retinal amacrine cells: 40.4;Retinal bipolar cells: 21.5;Retinal ganglion cells: 42.5;Retinal horizontal cells: 34.1;Somatotrophs: 22.6;Thyrotrophs: 15.4" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in some" 7 "Glioblastoma Multiforme (TCGA): 9.4;Pancreatic Adenocarcinoma (TCGA): 2.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 7.5;Neuroblastoma: 27.1" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" HPA045126 Uncertain Approved "Nucleoli rim,Mitotic chromosome" Yes NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 28 "Nucleoli rim" "Mitotic chromosome" "HPA045126: " "unprognostic (5.10e-2)" "unprognostic (3.08e-3)" "unprognostic (3.21e-3)" ACTL7A ENSG00000187003 "Actin like 7A" Q9Y615 9 108862266-108863756 "Predicted intracellular proteins" "Differentiation, Fertilization, Spermatogenesis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1180 "testis: 218.7" "Cell type enriched" "Detected in some" 4 "Late spermatids: 7542.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA021624 Enhanced Supported "Perinuclear theca" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 3 "Perinuclear theca" "HPA021624: " ACTL7B Tact1 ENSG00000148156 "Actin like 7B" Q9Y614 9 108854588-108855986 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1280 "testis: 202.8" "Group enriched" "Detected in some" 37 "Early spermatids: 1897.0;Late primary spermatocytes: 668.9;Late spermatids: 520.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 11 "lung cancer: 1.0" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA021803, HPA024664" Enhanced NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 11: Neuronal - Sensory perception" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 3 "HPA021803: , HPA024664: " ACTL8 CT57 ENSG00000117148 "Actin like 8" Q9H568 1 17755333-17827063 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 8 "testis: 6.8" "Cell type enriched" "Detected in some" 5 "Oocytes: 497.3" "Cell type enhanced" "Detected in some" "fibroblast: 1.1;mammillary body: 1.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 27.0" "Testis - Spermatogonia" "Not detected" "Not detected" HPA027176 Approved Cytosol NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 39: Non-specific - Transcription" "Cluster 41: Oocytes - Oogenesis" 2 Cytosol "HPA027176: " "unprognostic (2.50e-3)" "unprognostic (2.52e-3)" "unprognostic (4.05e-2)" "unprognostic (2.78e-1)" "unprognostic (1.69e-1)" "unprognostic (3.10e-1)" "potential prognostic unfavorable (1.00e-4)" "potential prognostic unfavorable (1.27e-4)" "unprognostic (2.14e-2)" "unprognostic (4.74e-2)" "unprognostic (1.69e-1)" "unprognostic (1.97e-1)" "unprognostic (9.25e-2)" "unprognostic (1.86e-1)" "unprognostic (7.86e-2)" "unprognostic (9.43e-3)" ACTL9 MGC33407 ENSG00000181786 "Actin like 9" Q8TC94 19 8697400-8698795 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Fertilization "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1083 "testis: 108.2" "Group enriched" "Detected in some" 10 "Early spermatids: 1198.6;Late spermatids: 3435.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA019231, HPA026693" Uncertain Supported "Acrosome,Equatorial segment" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" "Acrosome, Equatorial segment" "HPA019231: , HPA026693: " ACTN1 ENSG00000072110 "Actinin alpha 1" P12814 14 68874128-68979440 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "smooth muscle: 499.3" "Cell type enhanced" "Detected in all" "Breast myoepithelial cells: 568.3;Extravillous trophoblasts: 605.4;Neutrophil progenitors: 575.2;Neutrophils: 1047.8;Platelets: 1147.7;Salivary myoepithelial cells: 964.6;Smooth muscle cells: 947.7" "Cell type enhanced" "Detected in all" "vascular associated smooth muscle cell: 424.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 346.0" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 1086.0" "Breast - Breast myoepithelial cells, Colon - Smooth muscle cells, Lung - Smooth muscle cells, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Endothelial cells, Prostate - Smooth muscle cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004303, HPA006035" Approved Approved "Plasma membrane,Actin filaments,Focal adhesion sites,Primary cilium,Primary cilium transition zone,Cytosol" NA NA 320000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 62: Smooth muscle cells - Muscle contraction" 97 "Plasma membrane, Actin filaments, Focal adhesion sites" "Primary cilium, Primary cilium transition zone, Cytosol" "CAB004303: , HPA006035: " "unprognostic (1.11e-1)" "unprognostic (1.53e-1)" "unprognostic (3.73e-2)" "potential prognostic unfavorable (1.49e-4)" "unprognostic (2.42e-1)" "unprognostic (3.28e-2)" "unprognostic (4.79e-2)" "unprognostic (8.30e-2)" "unprognostic (1.86e-3)" "unprognostic (2.64e-2)" "unprognostic (2.47e-3)" "unprognostic (2.33e-1)" "potential prognostic unfavorable (1.38e-5)" "unprognostic (2.64e-3)" "unprognostic (3.88e-3)" "unprognostic (1.87e-3)" "potential prognostic unfavorable (3.40e-4)" "unprognostic (5.31e-2)" "unprognostic (4.19e-3)" "unprognostic (1.87e-2)" "unprognostic (3.56e-2)" "unprognostic (5.56e-2)" "unprognostic (2.57e-1)" "unprognostic (4.07e-1)" "unprognostic (4.24e-3)" "unprognostic (6.92e-2)" "unprognostic (8.09e-2)" "unprognostic (2.17e-2)" "unprognostic (1.98e-1)" "unprognostic (3.71e-2)" "unprognostic (2.14e-1)" ACTN2 ENSG00000077522 "Actinin alpha 2" P35609 1 236664141-236764631 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" Actin-binding "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 35 "heart muscle: 695.9;skeletal muscle: 1961.6;tongue: 1195.2" "Group enriched" "Detected in many" 10 "Cardiomyocytes: 1857.8;Myonuclei: 2582.4;Thymic myoid cells: 1051.0" "Cell type enhanced" "Detected in all" "mammillary body: 315.0" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 8.0;Head and Neck Squamous Cell Carcinoma (TCGA): 13.2" "Region enhanced" "Detected in many" "basal ganglia: 12.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Bone cancer: 1.5;Sarcoma: 1.7" "Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes" "Region enhanced" "Detected in many" "basal ganglia: 66.6" "Region enhanced" "Detected in all" "basal ganglia: 42.5" "HPA006035, HPA008315" Enhanced Approved "Actin filaments,Focal adhesion sites,Primary cilium,Primary cilium transition zone,Cytosol" NA NA 32000000 "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 33: Neurons - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 55: Myocytes - Oxidative muscle function" 105 "Actin filaments, Focal adhesion sites" "Primary cilium, Primary cilium transition zone, Cytosol" "HPA006035: , HPA008315: " "unprognostic (2.55e-1)" "unprognostic (1.96e-1)" "unprognostic (9.50e-2)" "unprognostic (7.79e-3)" "unprognostic (1.53e-1)" "unprognostic (5.82e-2)" "unprognostic (3.69e-1)" "unprognostic (4.50e-2)" ACTN3 ENSG00000248746 "Actinin alpha 3" Q08043 11 66546395-66563334 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 72 "skeletal muscle: 1567.3" "Group enriched" "Detected in some" 6 "Late spermatids: 29.7;Myonuclei: 46.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Rhabdoid: 5.5" "Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA006035 Uncertain Approved "Actin filaments,Focal adhesion sites,Primary cilium,Primary cilium transition zone,Cytosol" NA NA 18000000 "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 15: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 53 "Actin filaments, Focal adhesion sites" "Primary cilium, Primary cilium transition zone, Cytosol" "HPA006035: " ACTN4 FSGS1 ENSG00000130402 "Actinin alpha 4" O43707 19 38647649-38731589 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 539.7" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 148.0;Distal convoluted tubule cells: 248.8;Ependymal cells: 195.9;Loop of henle epithelial cells: 206.1;Oligodendrocytes: 150.6;Papillary tip epithelial cells: 279.2;Podocytes: 1068.5;Proximal tubule cells: 261.0;Renal collecting duct intercalated cells: 238.3;Renal collecting duct principal cells: 209.1;Renal connecting tubule cells: 376.3" "Cell type enhanced" "Detected in all" "vascular associated smooth muscle cell: 671.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001873, HPA006035" Supported Approved "Actin filaments,Focal adhesion sites,Primary cilium,Primary cilium transition zone,Cytosol" NA NA 99000000 "Cluster 7: Non-specific - Innate immune response" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 11: White matter - Signal transduction" "Cluster 4: Non-specific - Transcription" "Cluster 57: Podocytes - Glomerular filtration" 88 "Actin filaments, Focal adhesion sites" "Primary cilium, Primary cilium transition zone, Cytosol" "HPA001873: , HPA006035: " "unprognostic (2.67e-1)" "unprognostic (1.33e-1)" "unprognostic (1.28e-1)" "unprognostic (2.03e-3)" "unprognostic (5.65e-2)" "unprognostic (2.24e-1)" "unprognostic (3.17e-1)" "unprognostic (1.82e-2)" "unprognostic (3.45e-1)" "unprognostic (3.89e-2)" "potential prognostic favorable (7.31e-9)" "unprognostic (3.64e-3)" "unprognostic (1.50e-1)" "unprognostic (2.04e-1)" "unprognostic (8.91e-2)" "unprognostic (5.41e-3)" "unprognostic (1.42e-1)" "unprognostic (7.24e-3)" "unprognostic (1.51e-1)" "unprognostic (6.54e-2)" "unprognostic (1.51e-1)" "unprognostic (8.85e-3)" "unprognostic (2.17e-2)" "unprognostic (2.98e-1)" "unprognostic (6.56e-2)" "unprognostic (2.51e-2)" "unprognostic (1.90e-1)" "unprognostic (2.41e-1)" "unprognostic (9.50e-2)" "unprognostic (1.13e-1)" "unprognostic (2.13e-2)" ACTR10 "ACTR11, Arp10, Arp11, HARP11" ENSG00000131966 "Actin related protein 10" Q9NZ32 14 58200080-58235636 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in all" 8 "Bile duct cancer: 55.7" "Skeletal muscle - Fibroblasts, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000699 Approved "Vesicles,Plasma membrane,Focal adhesion sites,Perinuclear theca,Connecting piece,Flagellar centriole,Mid piece,Principal piece" NA NA "Cluster 32: Basophils - Transcription" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 38 "Vesicles, Plasma membrane" "Focal adhesion sites, Perinuclear theca, Connecting piece, Flagellar centriole, Mid piece, Principal piece" "HPA000699: " "unprognostic (1.94e-1)" "unprognostic (4.14e-1)" "unprognostic (4.39e-3)" "unprognostic (8.62e-3)" "unprognostic (1.58e-2)" "unprognostic (6.15e-2)" "unprognostic (1.51e-1)" "unprognostic (1.43e-1)" "unprognostic (6.34e-2)" "unprognostic (7.15e-2)" "unprognostic (1.06e-2)" "unprognostic (1.12e-1)" "unprognostic (2.23e-2)" "unprognostic (1.60e-3)" "unprognostic (8.08e-2)" "unprognostic (2.94e-2)" "unprognostic (8.92e-2)" "unprognostic (3.90e-3)" "unprognostic (3.12e-1)" "unprognostic (1.17e-1)" "potential prognostic unfavorable (9.28e-4)" "potential prognostic favorable (1.87e-4)" "unprognostic (4.44e-2)" "unprognostic (1.25e-1)" "unprognostic (9.21e-3)" "unprognostic (1.01e-1)" "unprognostic (1.02e-1)" "unprognostic (1.22e-1)" "unprognostic (1.19e-1)" "unprognostic (2.51e-1)" "unprognostic (1.09e-1)" ACTR1A "ARP1, Arp1A" ENSG00000138107 "Actin related protein 1A" P61163 10 102461881-102502712 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 183.2;Syncytiotrophoblasts: 157.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Endothelial cells, Prostate - Smooth muscle cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037193, HPA047443" Approved Uncertain "Microtubules,Cytokinetic bridge,Primary cilium,Cytosol" Yes NA 650000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 93 Microtubules "Cytokinetic bridge, Primary cilium, Cytosol" "CAB037193: , HPA047443: " "unprognostic (1.48e-1)" "unprognostic (3.32e-3)" "unprognostic (4.39e-1)" "unprognostic (1.07e-1)" "unprognostic (4.87e-2)" "unprognostic (8.24e-2)" "unprognostic (1.88e-1)" "potential prognostic favorable (4.11e-8)" "unprognostic (5.85e-2)" "unprognostic (2.31e-1)" "unprognostic (4.27e-3)" "unprognostic (1.57e-1)" "potential prognostic favorable (4.79e-4)" "potential prognostic unfavorable (5.74e-4)" "unprognostic (1.80e-1)" "unprognostic (2.12e-2)" "unprognostic (2.32e-1)" "unprognostic (5.11e-2)" "unprognostic (1.64e-2)" "unprognostic (5.00e-2)" "unprognostic (4.40e-3)" "unprognostic (6.08e-2)" "unprognostic (1.93e-1)" "unprognostic (1.82e-1)" "unprognostic (1.73e-1)" "unprognostic (1.97e-1)" "unprognostic (4.29e-2)" "unprognostic (2.28e-1)" "unprognostic (2.68e-1)" "unprognostic (4.78e-2)" "unprognostic (1.36e-1)" ACTR1B "Arp1B, CTRN2" ENSG00000115073 "Actin related protein 1B" P42025 2 97655939-97664044 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047443 Uncertain "Microtubules,Cytokinetic bridge,Primary cilium,Cytosol" Yes NA 240000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 24: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 97: Non-specific - Cellular respiration" 50 Microtubules "Cytokinetic bridge, Primary cilium, Cytosol" "HPA047443: " "unprognostic (8.58e-3)" "unprognostic (3.83e-3)" "unprognostic (1.60e-1)" "unprognostic (1.56e-1)" "unprognostic (8.45e-2)" "unprognostic (8.09e-2)" "unprognostic (3.05e-3)" "unprognostic (1.76e-2)" "unprognostic (1.69e-1)" "unprognostic (2.46e-1)" "potential prognostic favorable (2.93e-5)" "unprognostic (4.09e-2)" "unprognostic (1.09e-2)" "unprognostic (4.83e-3)" "unprognostic (1.61e-3)" "unprognostic (1.98e-2)" "unprognostic (9.76e-2)" "unprognostic (2.24e-1)" "unprognostic (7.64e-2)" "unprognostic (4.38e-1)" "unprognostic (2.13e-1)" "unprognostic (1.94e-1)" "unprognostic (1.79e-2)" "unprognostic (3.01e-1)" "unprognostic (9.24e-2)" "unprognostic (1.21e-1)" "unprognostic (1.15e-1)" "unprognostic (1.99e-1)" "unprognostic (3.68e-2)" "unprognostic (7.94e-2)" "unprognostic (3.78e-1)" ACTR2 ARP2 ENSG00000138071 "Actin related protein 2" P61160 2 65227788-65271253 "Essential proteins, Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Monocyte progenitors: 1096.6;monocytes: 892.5;Neutrophil progenitors: 1466.5;Neutrophils: 2012.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005083, HPA015050" Approved Uncertain Nucleoli,Cytosol NA NA 16000000 "Cluster 41: Basophils - Unknown function" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 14: Neurons - Synaptic function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 125 Cytosol Nucleoli "CAB005083: , HPA015050: " "unprognostic (3.73e-2)" "unprognostic (5.02e-2)" "unprognostic (3.58e-1)" "potential prognostic unfavorable (1.36e-4)" "unprognostic (2.09e-1)" "unprognostic (9.36e-3)" "unprognostic (2.00e-1)" "unprognostic (3.07e-2)" "unprognostic (1.46e-1)" "potential prognostic unfavorable (6.91e-4)" "potential prognostic favorable (3.43e-5)" "unprognostic (2.48e-1)" "unprognostic (1.82e-1)" "unprognostic (1.37e-3)" "unprognostic (1.67e-2)" "potential prognostic unfavorable (9.63e-5)" "unprognostic (2.06e-2)" "unprognostic (6.10e-2)" "unprognostic (2.71e-1)" "unprognostic (8.75e-2)" "unprognostic (5.78e-3)" "unprognostic (1.42e-2)" "unprognostic (6.23e-2)" "unprognostic (5.34e-2)" "unprognostic (3.25e-1)" "unprognostic (6.76e-2)" "unprognostic (5.52e-2)" "unprognostic (6.95e-2)" "unprognostic (4.14e-1)" "unprognostic (2.53e-3)" "unprognostic (1.15e-1)" ACTR3 ARP3 ENSG00000115091 "Actin related protein 3" P61158 2 113890063-113962596 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1047.8;Megakaryocytes: 1193.1;Neutrophil progenitors: 1358.6;Neutrophils: 2891.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005085, HPA047016, HPA051683" Approved NA NA 18000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 21: Non-specific - Metabolism" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 75 "CAB005085: , HPA047016: , HPA051683: " "unprognostic (7.78e-2)" "unprognostic (2.63e-1)" "unprognostic (7.44e-2)" "potential prognostic unfavorable (3.01e-5)" "unprognostic (3.19e-2)" "unprognostic (1.71e-1)" "unprognostic (4.15e-1)" "unprognostic (1.52e-1)" "unprognostic (4.54e-2)" "unprognostic (6.40e-3)" "potential prognostic favorable (1.85e-5)" "unprognostic (5.21e-2)" "unprognostic (2.29e-2)" "unprognostic (7.11e-3)" "unprognostic (4.46e-2)" "unprognostic (3.49e-3)" "potential prognostic unfavorable (1.36e-5)" "unprognostic (3.09e-1)" "unprognostic (7.31e-2)" "unprognostic (1.78e-1)" "unprognostic (5.95e-3)" "unprognostic (6.45e-3)" "unprognostic (1.46e-1)" "unprognostic (1.61e-1)" "unprognostic (2.39e-1)" "unprognostic (2.74e-1)" "unprognostic (1.91e-1)" "unprognostic (1.50e-1)" "unprognostic (1.10e-1)" "unprognostic (6.02e-2)" "unprognostic (2.85e-1)" ACTR3B "ARP11, ARP3beta" ENSG00000133627 "Actin related protein 3B" Q9P1U1 7 152759749-152855378 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 51.8" "Cell type enhanced" "Detected in many" "Myonuclei: 130.0;Platelets: 195.2;Somatotrophs: 141.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells (progenitors), Pituitary gland - Somatotropes, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047016, HPA051683" Uncertain NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 34 "HPA047016: , HPA051683: " "unprognostic (9.00e-3)" "unprognostic (1.88e-1)" "unprognostic (3.19e-1)" "unprognostic (3.33e-1)" "unprognostic (6.27e-2)" "unprognostic (1.28e-1)" "unprognostic (9.85e-2)" "unprognostic (5.81e-2)" "unprognostic (4.05e-1)" "unprognostic (2.59e-3)" "potential prognostic favorable (4.23e-4)" "unprognostic (5.67e-2)" "unprognostic (7.02e-3)" "potential prognostic unfavorable (5.20e-4)" "unprognostic (1.29e-3)" "unprognostic (1.86e-2)" "unprognostic (1.92e-3)" "unprognostic (7.19e-2)" "unprognostic (1.50e-2)" "unprognostic (1.12e-2)" "unprognostic (2.18e-1)" "unprognostic (3.32e-2)" "unprognostic (1.86e-1)" "unprognostic (8.10e-3)" "unprognostic (1.78e-2)" "unprognostic (3.33e-1)" "unprognostic (2.04e-1)" "unprognostic (3.37e-3)" "unprognostic (8.47e-3)" "unprognostic (1.12e-1)" "unprognostic (5.01e-2)" ACTR3C ARP11 ENSG00000106526 "Actin related protein 3C" Q9C0K3 7 150243916-150323725 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 53.3" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 132.3;Choroid plexus epithelial cells: 155.1;Distal convoluted tubule cells: 212.7;Loop of henle epithelial cells: 159.4;Renal collecting duct intercalated cells: 169.8;Renal collecting duct principal cells: 143.6;Renal connecting tubule cells: 192.7;Retinal pigment epithelial cells: 144.9;Salivary ionocytes: 151.6" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 112.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Kidney cancer: 31.1" "Liver - Hepatocytes, Lung - Alveolar cells type 2, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" "unprognostic (2.63e-2)" "unprognostic (1.71e-1)" "unprognostic (1.23e-1)" "unprognostic (7.36e-2)" "unprognostic (8.89e-2)" "unprognostic (3.07e-1)" "potential prognostic unfavorable (4.24e-5)" "unprognostic (2.10e-2)" "unprognostic (3.29e-1)" "unprognostic (3.64e-2)" "unprognostic (3.18e-2)" "unprognostic (3.74e-1)" "unprognostic (1.33e-1)" "unprognostic (3.05e-2)" "unprognostic (4.91e-2)" "unprognostic (5.40e-2)" "unprognostic (8.32e-2)" "unprognostic (1.07e-1)" "unprognostic (1.87e-2)" "unprognostic (1.31e-1)" "unprognostic (5.08e-2)" "unprognostic (2.69e-3)" "unprognostic (2.34e-2)" "unprognostic (8.70e-2)" "unprognostic (6.29e-2)" "unprognostic (3.26e-2)" "unprognostic (7.71e-2)" "unprognostic (4.85e-2)" "unprognostic (3.50e-1)" "unprognostic (3.12e-2)" "unprognostic (2.56e-1)" ACTR5 "Arp5, FLJ12785, INO80M" ENSG00000101442 "Actin related protein 5" Q9H9F9 20 38748460-38772520 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 24.0;Late primary spermatocytes: 24.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042676 Approved NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 34: Non-specific - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 51 "HPA042676: " "unprognostic (2.82e-1)" "unprognostic (2.58e-2)" "unprognostic (4.20e-2)" "unprognostic (1.10e-1)" "unprognostic (3.07e-1)" "unprognostic (3.21e-1)" "unprognostic (8.22e-2)" "unprognostic (2.27e-2)" "unprognostic (3.64e-1)" "unprognostic (3.67e-2)" "unprognostic (1.33e-1)" "unprognostic (3.40e-1)" "unprognostic (2.96e-1)" "potential prognostic unfavorable (1.26e-6)" "unprognostic (1.58e-1)" "unprognostic (1.60e-1)" "unprognostic (5.36e-3)" "unprognostic (9.77e-2)" "unprognostic (1.10e-1)" "unprognostic (3.59e-2)" "unprognostic (2.65e-1)" "unprognostic (4.58e-2)" "unprognostic (4.97e-2)" "unprognostic (5.39e-2)" "unprognostic (7.31e-2)" "unprognostic (1.18e-3)" "unprognostic (1.08e-1)" "unprognostic (8.23e-3)" "unprognostic (3.47e-1)" "unprognostic (1.24e-1)" "unprognostic (5.43e-2)" ACTR6 "ARP6, FLJ13433" ENSG00000075089 "Actin related protein 6" Q9GZN1 12 100199122-100241865 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 136.5;Late primary spermatocytes: 180.3;Syncytiotrophoblasts: 134.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038587, HPA038588" Uncertain Approved "Plasma membrane,Cytosol" No No "Cluster 3: Non-specific - Nuclear processes" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 27: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 24 "Plasma membrane, Cytosol" "HPA038587: , HPA038588: " "unprognostic (2.99e-1)" "unprognostic (3.69e-3)" "unprognostic (5.45e-2)" "unprognostic (1.01e-1)" "unprognostic (9.26e-2)" "unprognostic (2.48e-1)" "unprognostic (2.60e-1)" "unprognostic (2.62e-1)" "unprognostic (3.63e-3)" "potential prognostic unfavorable (1.33e-4)" "validated prognostic favorable (2.53e-6)" "validated prognostic favorable (9.92e-4)" "unprognostic (1.28e-1)" "potential prognostic unfavorable (4.51e-10)" "unprognostic (1.06e-3)" "unprognostic (2.05e-2)" "unprognostic (2.52e-1)" "unprognostic (9.46e-2)" "unprognostic (2.49e-1)" "unprognostic (4.90e-2)" "unprognostic (2.95e-3)" "unprognostic (2.24e-2)" "unprognostic (2.32e-2)" "unprognostic (5.57e-1)" "unprognostic (4.76e-2)" "unprognostic (3.54e-1)" "unprognostic (2.91e-1)" "unprognostic (1.14e-1)" "unprognostic (2.01e-1)" "unprognostic (9.22e-2)" "unprognostic (7.65e-2)" ACTR8 "ARP8, INO80N" ENSG00000113812 "Actin related protein 8" Q9H981 3 53867066-53882152 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA recombination, DNA repair, Mitosis, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 59.6;Late spermatids: 133.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 56.4" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065236 Supported Nucleoplasm,Centrosome NA NA "Cluster 32: Basophils - Transcription" "Cluster 35: Non-specific - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 39 Nucleoplasm Centrosome "HPA065236: " "unprognostic (4.26e-2)" "unprognostic (5.99e-2)" "unprognostic (1.83e-1)" "unprognostic (3.04e-1)" "unprognostic (1.37e-2)" "unprognostic (3.80e-1)" "unprognostic (1.69e-2)" "unprognostic (5.84e-2)" "unprognostic (1.68e-1)" "unprognostic (6.16e-3)" "potential prognostic favorable (3.12e-7)" "unprognostic (1.07e-2)" "unprognostic (6.22e-3)" "potential prognostic unfavorable (1.59e-7)" "unprognostic (1.68e-2)" "unprognostic (7.39e-2)" "unprognostic (1.04e-3)" "unprognostic (5.27e-2)" "unprognostic (9.29e-2)" "unprognostic (2.00e-1)" "unprognostic (2.29e-2)" "unprognostic (9.16e-2)" "unprognostic (2.10e-1)" "unprognostic (3.12e-2)" "potential prognostic favorable (1.74e-4)" "unprognostic (1.57e-1)" "unprognostic (2.30e-1)" "unprognostic (2.72e-1)" "unprognostic (2.45e-1)" "unprognostic (1.69e-1)" "unprognostic (1.99e-1)" ACTRT1 "AIP1, ARIP1, Arp-T1, KIAA0705" ENSG00000123165 "Actin related protein T1" Q8TDG2 X 128050962-128052403 "Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 40 "testis: 3.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA003119 Supported NA NA "Cluster 79: Testis - Spermatogenesis" 8 "HPA003119: " ACTRT2 "ACTRT2, Arp-T2, ARPM2, FLJ25424" ENSG00000169717 "Actin related protein T2" Q8TDY3 1 3021467-3022903 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1238 "testis: 146.1" "Group enriched" "Detected in some" 8 "Early spermatids: 1435.0;Late spermatids: 5694.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA006480, HPA025079" Enhanced NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 9 "HPA006480: , HPA025079: " ACTRT3 ARPM1 ENSG00000184378 "Actin related protein T3" Q9BYD9 3 169766921-169769561 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 19 "testis: 54.1" "Group enriched" "Detected in many" 5 "Early spermatids: 1180.4;Late primary spermatocytes: 533.9" "Low cell type specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA035817, HPA035818" Approved Approved Nucleoplasm,Centrosome,Cytosol,Acrosome NA NA "Cluster 67: Testis - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 2 Nucleoplasm "Centrosome, Cytosol, Acrosome" "HPA035817: , HPA035818: " "unprognostic (1.47e-2)" "unprognostic (1.57e-1)" "unprognostic (4.99e-2)" "unprognostic (3.48e-1)" "unprognostic (1.01e-1)" "unprognostic (2.50e-1)" "unprognostic (1.31e-1)" "unprognostic (5.70e-3)" "unprognostic (6.91e-3)" "unprognostic (9.70e-2)" "unprognostic (3.80e-1)" "unprognostic (3.64e-3)" "unprognostic (1.26e-1)" "unprognostic (4.67e-2)" "unprognostic (9.98e-3)" "unprognostic (6.61e-2)" "unprognostic (1.16e-2)" "unprognostic (2.72e-2)" "unprognostic (2.74e-2)" "unprognostic (4.53e-3)" "unprognostic (5.73e-2)" "unprognostic (1.90e-2)" "unprognostic (1.10e-1)" "unprognostic (2.96e-1)" "potential prognostic unfavorable (9.16e-4)" "unprognostic (1.33e-2)" ACVR1 "ACVR1A, ACVRLK2, ALK2, SKR1" ENSG00000115170 "Activin A receptor type 1" Q04771 2 157736251-157876330 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 202.3;Proximal tubule cells: 222.5;Salivary ionocytes: 202.3" "Cell type enhanced" "Detected in all" "endothelial cell: 743.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 5.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007505 Approved NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 75: Ovary - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 104: Brain endothelial cells - Blood brain barrier" 14 "HPA007505: " "unprognostic (2.02e-1)" "unprognostic (1.19e-1)" "unprognostic (5.75e-2)" "unprognostic (6.85e-2)" "unprognostic (1.63e-1)" "potential prognostic unfavorable (7.38e-5)" "unprognostic (1.94e-1)" "unprognostic (3.72e-1)" "unprognostic (3.50e-2)" "unprognostic (5.89e-2)" "potential prognostic favorable (1.95e-4)" "unprognostic (6.83e-2)" "unprognostic (3.69e-3)" "unprognostic (1.30e-3)" "unprognostic (9.03e-3)" "unprognostic (1.14e-1)" "unprognostic (2.31e-2)" "unprognostic (2.39e-1)" "unprognostic (1.53e-1)" "unprognostic (5.48e-2)" "unprognostic (3.03e-2)" "unprognostic (5.91e-2)" "unprognostic (4.19e-1)" "unprognostic (3.25e-2)" "unprognostic (1.31e-1)" "unprognostic (8.28e-3)" "unprognostic (3.62e-1)" "unprognostic (4.08e-3)" "unprognostic (3.35e-1)" "unprognostic (1.91e-2)" "unprognostic (6.36e-2)" ACVR1B "ActRIB, ACVRLK4, ALK4, SKR2" ENSG00000135503 "Activin A receptor type 1B" P36896 12 51951699-51997078 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 186.3;Neutrophils: 160.8;Renal connecting tubule cells: 182.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 3.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026126, HPA063761" Approved Approved "Vesicles,Primary cilium,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 53: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 16 Cytosol "Vesicles, Primary cilium" "CAB026126: , HPA063761: " "unprognostic (4.44e-1)" "unprognostic (3.54e-2)" "unprognostic (1.61e-1)" "unprognostic (1.13e-1)" "unprognostic (9.77e-2)" "unprognostic (2.03e-2)" "unprognostic (3.42e-1)" "unprognostic (6.70e-3)" "unprognostic (1.82e-1)" "unprognostic (2.75e-1)" "unprognostic (1.22e-2)" "unprognostic (4.91e-3)" "unprognostic (1.30e-1)" "unprognostic (1.17e-3)" "unprognostic (4.44e-2)" "unprognostic (4.47e-2)" "unprognostic (1.63e-1)" "unprognostic (1.02e-1)" "unprognostic (2.60e-2)" "unprognostic (2.65e-1)" "unprognostic (5.59e-1)" "unprognostic (1.37e-1)" "unprognostic (1.47e-3)" "unprognostic (9.58e-2)" "unprognostic (9.62e-2)" "unprognostic (1.20e-1)" "unprognostic (1.12e-1)" "unprognostic (1.46e-1)" "unprognostic (1.08e-2)" "unprognostic (7.34e-2)" "unprognostic (2.51e-1)" ACVR1C "ACVRLK7, ALK7" ENSG00000123612 "Activin A receptor type 1C" Q8NER5 2 157526767-157628864 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "adipose tissue: 29.3" "Cell type enhanced" "Detected in many" "Adipocytes: 361.7;Adrenal medulla cells: 138.3;Bergmann glia: 115.7;Leydig cells: 82.3;Somatotrophs: 63.8" "Cell type enhanced" "Detected in many" "Bergmann glia: 116.8;hippocampal CA4: 120.1;hippocampal dentate gyrus: 160.4" "Cancer enhanced" "Detected in some" "Kidney Chromophobe (TCGA): 3.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 6.3" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal medulla cells, Breast - Adipocytes (Breast), Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Somatotropes" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 38.9" "HPA007982, HPA011933" Uncertain "Intracellular and membrane" Receptor NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 33: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 89: Adipocytes - Lipid metabolism" "HPA007982: , HPA011933: " "unprognostic (4.57e-2)" "unprognostic (3.48e-1)" "unprognostic (1.44e-2)" "unprognostic (1.47e-1)" "unprognostic (1.14e-1)" "unprognostic (1.94e-1)" "unprognostic (2.15e-2)" "unprognostic (1.08e-1)" "unprognostic (2.11e-3)" "unprognostic (7.06e-3)" "unprognostic (3.36e-2)" "unprognostic (8.70e-2)" ACVR2A "ACTRII, ACVR2" ENSG00000121989 "Activin A receptor type 2A" P27037 2 147844517-147930826 "Cancer-related genes, Enzymes, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046997 Approved Approved Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 37: Skin - Keratinization" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 9: T-cells - Adaptive immunity: Regulation" 34 Cytosol "HPA046997: " "unprognostic (1.63e-1)" "unprognostic (2.04e-2)" "unprognostic (3.55e-1)" "unprognostic (9.26e-2)" "unprognostic (1.12e-1)" "unprognostic (2.27e-1)" "unprognostic (3.28e-1)" "unprognostic (8.00e-3)" "unprognostic (9.63e-2)" "unprognostic (2.26e-2)" "validated prognostic favorable (6.18e-9)" "validated prognostic favorable (9.12e-6)" "unprognostic (5.49e-2)" "unprognostic (7.15e-3)" "unprognostic (3.40e-1)" "unprognostic (2.07e-2)" "unprognostic (3.07e-1)" "unprognostic (1.86e-1)" "unprognostic (3.94e-2)" "unprognostic (4.37e-2)" "unprognostic (3.41e-2)" "unprognostic (2.44e-1)" "unprognostic (5.86e-2)" "unprognostic (1.99e-1)" "unprognostic (1.31e-2)" "unprognostic (7.49e-2)" "unprognostic (5.16e-2)" "unprognostic (7.10e-2)" "unprognostic (2.33e-1)" "unprognostic (9.52e-2)" "unprognostic (3.38e-1)" ACVR2B ActR-IIB ENSG00000114739 "Activin A receptor type 2B" Q13705 3 38453890-38493142 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Heterotaxy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 61.1;Thyrotrophs: 51.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 10.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "testis cancer: 13.6" "Adrenal gland - Adrenal cortex cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025115, HPA040384" Approved NA No "Cluster 25: Non-specific - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 34: Testis cancer - Unknown function" "Cluster 18: Adrenal cortex cells - Steroidogensis" 14 "CAB025115: , HPA040384: " "unprognostic (7.49e-2)" "unprognostic (1.22e-1)" "unprognostic (1.63e-1)" "unprognostic (2.19e-1)" "unprognostic (2.43e-2)" "unprognostic (1.31e-2)" "unprognostic (1.37e-1)" "unprognostic (1.39e-2)" "validated prognostic favorable (4.40e-6)" "validated prognostic favorable (1.93e-5)" "unprognostic (1.77e-1)" "unprognostic (6.70e-2)" "unprognostic (5.32e-2)" "unprognostic (1.96e-1)" "unprognostic (7.41e-2)" "unprognostic (3.01e-3)" "unprognostic (1.34e-1)" "unprognostic (3.85e-2)" "unprognostic (2.04e-1)" "unprognostic (6.75e-2)" "unprognostic (3.10e-1)" "unprognostic (4.69e-2)" "unprognostic (1.74e-2)" "unprognostic (2.21e-1)" "unprognostic (1.38e-1)" "unprognostic (2.24e-1)" "unprognostic (1.82e-2)" "unprognostic (1.80e-1)" ACVRL1 "ACVRLK1, ALK1, HHT, HHT2, ORW2" ENSG00000139567 "Activin A receptor like type 1" P37023 12 51906908-51923361 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 83.2" "Cell type enhanced" "Detected in many" "Colonocytes: 121.4;Decidual stromal cells: 29.5;Enteric transient amplifying cells: 27.5;Extravillous trophoblasts: 54.3;Fibroblasts: 53.4;Goblet cells: 29.0;Kupffer cells: 83.0;Lacrimal acinar cells: 25.4;Lymphatic endothelial cells: 69.6;Myosatellite cells: 27.7;Pericytes: 34.8;Vascular endothelial cells: 110.7" "Cell type enriched" "Detected in some" 6 "endothelial cell: 100.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 19 "classical monocyte: 1.5;myeloid DC: 2.1" "Group enriched" "Detected in many" 19 "dendritic cells: 2.1;monocytes: 1.5" "Cancer enhanced" "Detected in some" "Neuroblastoma: 8.0" "Minor Salivary Gland - Endothelial cells, Pituitary gland - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007041 Approved "Intracellular and membrane" Receptor NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 9 "HPA007041: " "unprognostic (1.39e-1)" "unprognostic (3.29e-1)" "unprognostic (1.07e-1)" "unprognostic (7.32e-2)" "unprognostic (3.68e-2)" "unprognostic (7.26e-2)" "unprognostic (3.76e-1)" "unprognostic (1.96e-2)" "unprognostic (3.44e-2)" "unprognostic (2.32e-1)" "validated prognostic favorable (2.51e-7)" "validated prognostic favorable (1.63e-4)" "unprognostic (3.06e-2)" "unprognostic (3.23e-1)" "unprognostic (1.30e-1)" "unprognostic (9.55e-2)" "unprognostic (7.44e-2)" "unprognostic (1.40e-3)" "unprognostic (4.53e-1)" "unprognostic (5.07e-2)" "unprognostic (4.38e-3)" "unprognostic (8.33e-2)" "unprognostic (4.39e-2)" "unprognostic (7.73e-3)" "unprognostic (6.10e-2)" "unprognostic (1.87e-1)" "unprognostic (1.66e-2)" "unprognostic (9.82e-2)" "unprognostic (8.21e-3)" "unprognostic (3.11e-1)" "unprognostic (2.54e-2)" ACY1 ENSG00000243989 "Aminoacylase 1" Q03154 3 51983340-51989197 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "intestine: 170.7;kidney: 420.7;liver: 257.3" "Group enriched" "Detected in some" 5 "Colonocytes: 32.3;Enterocytes: 126.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Sebaceous gland cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003695, HPA036174, HPA036175, HPA071834" Enhanced Approved Vesicles NA NA 19000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 16 Vesicles "CAB003695: , HPA036174: , HPA036175: , HPA071834: " "unprognostic (3.58e-1)" "unprognostic (2.73e-1)" "unprognostic (2.87e-1)" "unprognostic (6.45e-3)" "unprognostic (2.06e-1)" "unprognostic (1.86e-2)" "unprognostic (4.69e-1)" "unprognostic (2.85e-2)" "unprognostic (9.07e-2)" "unprognostic (9.34e-2)" "potential prognostic favorable (1.02e-6)" "unprognostic (4.89e-2)" "potential prognostic favorable (1.78e-5)" "unprognostic (2.16e-2)" "unprognostic (3.26e-2)" "unprognostic (9.09e-2)" "unprognostic (1.17e-2)" "unprognostic (9.78e-2)" "unprognostic (1.30e-2)" "unprognostic (4.26e-2)" "unprognostic (3.48e-1)" "potential prognostic unfavorable (2.86e-4)" "unprognostic (1.37e-1)" "unprognostic (7.35e-2)" "unprognostic (2.26e-1)" "unprognostic (3.54e-2)" "unprognostic (3.50e-1)" "unprognostic (1.67e-1)" "unprognostic (4.21e-1)" "unprognostic (5.78e-2)" "unprognostic (4.08e-2)" ACY3 "ACY-3, HCBP1, MGC9740" ENSG00000132744 "Aminoacylase 3" Q96HD9 11 67642555-67650730 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Host-virus interaction" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 73.0;kidney: 55.1;liver: 32.2;pancreas: 20.9" "Cell type enhanced" "Detected in some" "Enterocytes: 231.0;Epididymal efferent duct absorptive cells: 62.7;Foveolar cells: 20.1;Gastric chief cells: 24.0;Goblet cells: 50.3;Hepatocytes: 22.9;Microglia: 50.6;Submucosal glandular cells: 22.1;Thymocytes: 25.4" "Cell type enriched" "Detected in some" 18 "central nervous system macrophage: 53.5" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 40.8;Kidney Renal Papillary Cell Carcinoma (TCGA): 40.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 34.3" "Group enriched" "Detected in many" 5 "dendritic cells: 8.7;monocytes: 34.3" "Cancer enhanced" "Detected in many" "lymphoma: 18.2" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "HPA039219, HPA048187" Enhanced NA NA 32000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 1: Enterocytes - Absorption and Digestion" 19 "HPA039219: , HPA048187: " "unprognostic (1.90e-1)" "unprognostic (3.12e-3)" "unprognostic (1.76e-2)" "unprognostic (1.16e-1)" "unprognostic (1.80e-1)" "unprognostic (1.93e-3)" "unprognostic (3.11e-1)" "unprognostic (3.47e-2)" "unprognostic (1.17e-2)" "potential prognostic favorable (5.08e-6)" "unprognostic (2.13e-2)" "potential prognostic favorable (4.91e-4)" "unprognostic (2.40e-3)" "unprognostic (2.38e-3)" "unprognostic (2.86e-1)" "unprognostic (2.15e-2)" "unprognostic (2.30e-1)" "unprognostic (4.50e-3)" "potential prognostic favorable (1.45e-4)" "unprognostic (6.73e-2)" "unprognostic (2.69e-2)" "unprognostic (3.42e-1)" "unprognostic (2.22e-1)" "unprognostic (6.28e-3)" "unprognostic (1.29e-1)" "unprognostic (7.09e-2)" "unprognostic (1.14e-1)" ACYP1 ENSG00000119640 "Acylphosphatase 1" P07311 14 75053237-75069483 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 140.5;Epididymal efferent duct ciliated cells: 138.1;Fallopian tube ciliated cells: 147.3;Late primary spermatocytes: 134.9;Respiratory ciliated cells: 126.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" HPA034944 Approved Approved Nucleoplasm,Cytosol NA NA 100000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 107: Ciliated cells - Cilia assembly & function" Cytosol Nucleoplasm "HPA034944: " "unprognostic (2.07e-1)" "unprognostic (1.78e-3)" "unprognostic (1.84e-1)" "potential prognostic favorable (3.86e-4)" "unprognostic (8.30e-3)" "unprognostic (2.51e-1)" "unprognostic (2.98e-1)" "unprognostic (1.09e-2)" "unprognostic (2.92e-1)" "unprognostic (1.28e-3)" "unprognostic (2.19e-1)" "unprognostic (2.24e-2)" "unprognostic (9.35e-2)" "potential prognostic unfavorable (1.32e-7)" "unprognostic (2.78e-2)" "unprognostic (6.25e-2)" "unprognostic (2.32e-1)" "unprognostic (3.54e-2)" "unprognostic (9.22e-2)" "unprognostic (8.37e-2)" "unprognostic (1.72e-1)" "unprognostic (7.78e-3)" "unprognostic (9.51e-3)" "unprognostic (5.26e-2)" "unprognostic (5.56e-2)" "unprognostic (1.65e-1)" "unprognostic (2.47e-1)" "unprognostic (1.98e-2)" "unprognostic (1.04e-1)" "unprognostic (1.75e-1)" "unprognostic (3.51e-1)" ACYP2 ENSG00000170634 "Acylphosphatase 2" P14621 2 53970838-54305300 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 104.3;skeletal muscle: 191.3;tongue: 148.7" "Cell type enhanced" "Detected in all" "Myonuclei: 1235.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035301 Uncertain Approved Nucleoplasm NA NA 9800 "Cluster 46: Basophils - Proteolysis" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 2 Nucleoplasm "HPA035301: " "unprognostic (5.04e-2)" "unprognostic (1.42e-2)" "unprognostic (2.37e-1)" "unprognostic (2.12e-1)" "unprognostic (1.87e-1)" "unprognostic (2.77e-2)" "unprognostic (3.69e-3)" "unprognostic (3.63e-1)" "unprognostic (6.21e-2)" "unprognostic (1.63e-1)" "unprognostic (1.92e-1)" "unprognostic (6.43e-2)" "unprognostic (1.20e-1)" "unprognostic (1.75e-2)" "potential prognostic favorable (9.18e-5)" "unprognostic (4.37e-2)" "unprognostic (2.86e-3)" "unprognostic (1.12e-1)" "unprognostic (3.20e-1)" "potential prognostic favorable (7.97e-5)" "unprognostic (1.69e-1)" "unprognostic (1.34e-2)" "unprognostic (3.06e-2)" "unprognostic (3.32e-1)" "unprognostic (7.02e-2)" "unprognostic (1.97e-1)" "unprognostic (3.71e-2)" "unprognostic (3.01e-1)" "unprognostic (1.22e-1)" "unprognostic (1.06e-1)" "unprognostic (6.55e-2)" ADA ADA1 ENSG00000196839 "Adenosine deaminase" P00813 20 44584896-44652252 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Nucleotide metabolism" Hydrolase "Disease variant, FDA approved drug targets, Hereditary hemolytic anemia, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "intestine: 454.0;lymphoid tissue: 228.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 439.1;Extravillous trophoblasts: 213.3;Fibro-adipogenic progenitors: 109.6;monocytes: 87.1;Oocytes: 110.5;Parietal cells: 212.1;pDCs: 88.2" "Cell type enhanced" "Detected in some" "committed oligodendrocyte precursor: 9.8;leukocyte: 24.5;oligodendrocyte: 12.4;pericyte: 12.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "intermediate monocyte: 163.0;NK-cell: 90.4;non-classical monocyte: 351.2;plasmacytoid DC: 211.2" "Group enriched" "Detected in all" 4 "dendritic cells: 211.2;monocytes: 351.2;NK-cells: 90.4" "Cancer enhanced" "Detected in all" "Leukemia: 168.9" "Kidney - Endothelial cells, Minor Salivary Gland - Endothelial cells, Prostate - Fibroblasts, Stomach - Parietal cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001399, CAB004307, HPA023884, CAB080432" Enhanced Supported "Plasma membrane,Cytosol" No No 210000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 77: Intestine - Digestion" "Cluster 34: Non-specific - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 4 "Plasma membrane" Cytosol "CAB004307: , CAB080432: , HPA001399: , HPA023884: " "unprognostic (2.37e-2)" "unprognostic (1.78e-1)" "unprognostic (2.18e-2)" "unprognostic (8.81e-2)" "unprognostic (1.42e-1)" "unprognostic (1.95e-2)" "unprognostic (7.39e-2)" "unprognostic (1.70e-2)" "unprognostic (1.50e-2)" "unprognostic (3.97e-1)" "potential prognostic unfavorable (1.73e-5)" "unprognostic (3.05e-2)" "potential prognostic unfavorable (5.82e-5)" "potential prognostic unfavorable (1.35e-6)" "unprognostic (2.20e-2)" "potential prognostic unfavorable (6.28e-6)" "unprognostic (1.13e-2)" "unprognostic (2.01e-2)" "unprognostic (1.29e-1)" "unprognostic (1.90e-1)" "unprognostic (6.99e-2)" "unprognostic (3.57e-3)" "unprognostic (1.22e-3)" "unprognostic (7.92e-2)" "unprognostic (2.84e-1)" "unprognostic (4.38e-2)" "unprognostic (3.72e-2)" "unprognostic (1.30e-1)" "unprognostic (1.90e-1)" "unprognostic (2.48e-2)" "unprognostic (1.41e-3)" ADA2 "ADGF, CECR1, IDGFL" ENSG00000093072 "Adenosine deaminase 2" Q9NZK5 22 17178790-17258235 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Heparin-binding, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 106.4" "Cell type enhanced" "Detected in many" "cDC: 181.3;Early spermatids: 122.8;Kupffer cells: 338.2;Macrophages: 142.8;Monocyte progenitors: 124.0;monocytes: 244.0;pDCs: 100.6;Plasma cells: 116.4;Rod photoreceptor cells: 125.2" "Group enriched" "Detected in all" 4 "central nervous system macrophage: 78.0;leukocyte: 69.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Leukemia: 15.1;lymphoma: 7.8;Myeloma: 23.5;Rhabdoid: 7.1;testis cancer: 17.4" "Lung - Macrophages, Spleen - Macrophages, Testis - Late spermatids" "Low region specificity" "Detected in all" HPA007888 Uncertain "Secreted to blood" Enzyme NA NA 110000000 39000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" "HPA007888: " "unprognostic (3.55e-2)" "unprognostic (4.18e-2)" "unprognostic (2.92e-2)" "unprognostic (1.76e-1)" "unprognostic (2.68e-1)" "unprognostic (8.98e-2)" "unprognostic (2.46e-2)" "unprognostic (1.12e-2)" "unprognostic (5.05e-2)" "potential prognostic favorable (1.60e-5)" "unprognostic (2.11e-2)" "unprognostic (1.18e-3)" "unprognostic (2.44e-2)" "potential prognostic favorable (2.80e-5)" "unprognostic (1.70e-2)" "unprognostic (2.03e-2)" "unprognostic (3.16e-2)" "unprognostic (1.05e-1)" "unprognostic (2.80e-1)" "unprognostic (1.66e-2)" "unprognostic (1.87e-1)" "unprognostic (2.90e-2)" "unprognostic (5.63e-3)" "unprognostic (3.52e-2)" "unprognostic (9.62e-3)" "unprognostic (1.19e-2)" "unprognostic (9.00e-3)" "unprognostic (2.66e-1)" "unprognostic (1.87e-1)" ADAD1 Tenr ENSG00000164113 "Adenosine deaminase domain containing 1" Q96M93 4 122378966-122429802 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 185 "testis: 111.2" "Group enriched" "Detected in some" 15 "Early spermatids: 1044.3;Late primary spermatocytes: 967.8;Late spermatids: 1596.0" "Cell type enhanced" "Detected in single" "leukocyte: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Neuroblastoma: 2.3;thyroid cancer: 1.4" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 11: Neuronal - Sensory perception" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" ADAD2 "FLJ00337, TENRL" ENSG00000140955 "Adenosine deaminase domain containing 2" Q8NCV1 16 84191138-84197168 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "testis: 60.5" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 21.8;Early primary spermatocytes: 64.9;Early spermatids: 71.4;Esophageal apical cells: 22.6;Esophageal suprabasal cells: 27.2;Late primary spermatocytes: 172.3;Late spermatids: 28.0;Oocytes: 55.3;Retinal pigment epithelial cells: 268.6;Undifferentiated spermatogonia: 29.9" "Cell type enhanced" "Detected in some" "endothelial cell: 3.3;hippocampal dentate gyrus: 2.8" "Not detected" "Not detected" "Region enhanced" "Detected in many" "hippocampal formation: 5.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Minor Salivary Gland - Minor salivary gland basal cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA079443 Enhanced NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 29: Forebrain - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" "HPA079443: " ADAL ENSG00000168803 "Adenosine deaminase like" Q6DHV7 15 43330672-43354569 "Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 153.2;Undifferentiated spermatogonia: 79.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039879, HPA048175, HPA058795" Approved Approved "Nucleoplasm,Nuclear speckles,Vesicles" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 58: Non-specific - Nuclear processes" "Cluster 106: Spermatogonia - Spermatogonial differentiation" Nucleoplasm "Nuclear speckles, Vesicles" "HPA039879: , HPA048175: , HPA058795: " "unprognostic (2.74e-2)" "unprognostic (1.72e-1)" "unprognostic (8.60e-2)" "unprognostic (3.65e-2)" "unprognostic (9.59e-2)" "unprognostic (1.96e-2)" "unprognostic (4.93e-2)" "unprognostic (7.09e-2)" "unprognostic (9.32e-2)" "unprognostic (1.70e-2)" "potential prognostic favorable (1.22e-5)" "unprognostic (4.39e-2)" "unprognostic (3.15e-3)" "unprognostic (1.23e-1)" "unprognostic (8.28e-2)" "unprognostic (7.86e-2)" "unprognostic (1.35e-1)" "unprognostic (4.62e-2)" "unprognostic (3.72e-3)" "unprognostic (1.99e-1)" "unprognostic (1.94e-1)" "unprognostic (1.16e-1)" "unprognostic (3.74e-3)" "unprognostic (3.99e-2)" "unprognostic (2.24e-2)" "unprognostic (4.57e-1)" "unprognostic (5.65e-2)" "unprognostic (3.96e-2)" "unprognostic (1.18e-1)" "unprognostic (5.10e-2)" "unprognostic (2.52e-1)" ADAM10 "CD156C, HsT18717, kuz, MADM" ENSG00000137845 "ADAM metallopeptidase domain 10" O14672 15 58588809-58749791 "Cancer-related genes, CD markers, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Notch signaling pathway" "Hydrolase, Metalloprotease, Protease" "Alzheimer disease, Amyloidosis, Cancer-related genes, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 589.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001709, HPA050670" Approved Supported "Vesicles,Plasma membrane" "Intracellular and membrane" Enzyme NA NA 950000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 61: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 24: Neutrophils - Innate immunity signal integration" 41 "Vesicles, Plasma membrane" "CAB001709: , HPA050670: " "unprognostic (4.08e-2)" "unprognostic (5.03e-2)" "unprognostic (5.15e-2)" "potential prognostic unfavorable (3.94e-4)" "unprognostic (1.00e-1)" "unprognostic (1.57e-1)" "unprognostic (3.96e-1)" "unprognostic (9.59e-2)" "unprognostic (7.17e-3)" "unprognostic (1.11e-1)" "potential prognostic favorable (5.99e-6)" "unprognostic (1.15e-2)" "unprognostic (3.35e-1)" "unprognostic (1.48e-1)" "unprognostic (2.23e-1)" "potential prognostic unfavorable (9.44e-4)" "unprognostic (2.43e-3)" "unprognostic (5.70e-2)" "unprognostic (3.20e-1)" "unprognostic (2.74e-2)" "unprognostic (5.46e-3)" "potential prognostic unfavorable (2.06e-4)" "unprognostic (1.13e-2)" "unprognostic (1.18e-1)" "unprognostic (1.52e-1)" "unprognostic (1.05e-1)" "unprognostic (8.53e-2)" "unprognostic (1.51e-2)" "unprognostic (2.69e-1)" "unprognostic (6.59e-3)" "unprognostic (9.67e-3)" ADAM11 MDC ENSG00000073670 "ADAM metallopeptidase domain 11" O75078 17 44758988-44781846 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "brain: 91.2" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 57.7;Brain inhibitory neurons: 33.4;Late spermatids: 11.8;Other brain neurons: 13.1;Retinal amacrine cells: 55.9;Retinal ganglion cells: 23.2;Retinal horizontal cells: 58.1" "Cell type enhanced" "Detected in all" "cerebellar inhibitory: 210.3" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 2.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 6.6" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074550 Enhanced NA NA 23000 "Cluster 27: Cerebellum - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 11: Neuronal - Sensory perception" "Cluster 35: Neurons - Synaptic function & neurogenesis" "HPA074550: " "unprognostic (4.05e-1)" "unprognostic (1.50e-1)" "unprognostic (5.57e-2)" "unprognostic (1.45e-2)" ADAM12 "MCMPMltna, MLTN" ENSG00000148848 "ADAM metallopeptidase domain 12" O43184 10 126012381-126388477 "Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cell adhesion" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "placenta: 126.8" "Group enriched" "Detected in many" 4 "Extravillous trophoblasts: 1570.4;Mast cells: 479.7;Syncytiotrophoblasts: 617.3" "Cell type enhanced" "Detected in all" "cerebellar inhibitory: 292.4" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 24.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "MAIT T-cell: 4.5" "Lineage enriched" "Detected in single" 45 "T-cells: 4.5" "Cancer enhanced" "Detected in many" "Brain cancer: 41.1;Kidney cancer: 31.8" "Prostate - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA030866, HPA030867, HPA030868" Enhanced Supported "Plasma membrane" "Secreted in female reproductive system" "Cell adhesion" NA NA 14000000 "Cluster 1: T-cells - Unknown function" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 10 "Plasma membrane" "HPA030866: , HPA030867: , HPA030868: " "unprognostic (5.38e-2)" "unprognostic (2.73e-1)" "unprognostic (1.02e-1)" "unprognostic (2.42e-3)" "unprognostic (1.13e-2)" "unprognostic (6.50e-2)" "unprognostic (8.50e-2)" "unprognostic (1.11e-3)" "unprognostic (1.27e-1)" "unprognostic (1.80e-1)" "validated prognostic unfavorable (2.02e-5)" "validated prognostic unfavorable (3.63e-5)" "potential prognostic unfavorable (6.38e-4)" "unprognostic (1.69e-3)" "potential prognostic unfavorable (7.32e-4)" "unprognostic (2.04e-1)" "unprognostic (1.99e-1)" "unprognostic (4.71e-3)" "potential prognostic unfavorable (5.36e-5)" "unprognostic (4.10e-2)" "unprognostic (1.41e-1)" "unprognostic (9.85e-2)" "unprognostic (6.35e-3)" "unprognostic (9.98e-2)" "unprognostic (2.78e-3)" "unprognostic (2.52e-2)" "unprognostic (2.40e-3)" "unprognostic (6.36e-3)" ADAM15 MDC15 ENSG00000143537 "ADAM metallopeptidase domain 15" Q13444 1 155050566-155062775 "Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Cell adhesion, Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal suprabasal cells: 136.3;Extravillous trophoblasts: 262.5;Foveolar cells: 119.5;Respiratory deuterosomal cells: 128.5;Vascular endothelial cells: 172.2" "Cell type enhanced" "Detected in all" "endothelial cell: 104.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 39.1;intermediate monocyte: 26.5;myeloid DC: 64.1" "Group enriched" "Detected in all" 5 "dendritic cells: 64.1;monocytes: 39.1" "Low cancer specificity" "Detected in all" "Adrenal gland - Endothelial cells, Colon - Endothelial cells, Pancreas - Endothelial cells, Pituitary gland - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011633, HPA072878" Uncertain Uncertain Vesicles NA NA 360000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 58: Skin - Keratinization" "Cluster 19: Astrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 41 Vesicles "HPA011633: , HPA072878: " "unprognostic (4.65e-2)" "potential prognostic unfavorable (1.18e-4)" "unprognostic (1.71e-2)" "unprognostic (2.07e-1)" "unprognostic (2.27e-3)" "unprognostic (2.09e-3)" "unprognostic (1.72e-2)" "unprognostic (1.94e-1)" "unprognostic (5.66e-2)" "potential prognostic unfavorable (9.75e-4)" "unprognostic (3.22e-3)" "unprognostic (1.31e-1)" "unprognostic (2.26e-2)" "potential prognostic unfavorable (3.10e-4)" "unprognostic (2.32e-2)" "unprognostic (4.47e-2)" "unprognostic (5.15e-2)" "unprognostic (8.29e-2)" "unprognostic (1.11e-1)" "unprognostic (2.56e-1)" "unprognostic (1.22e-1)" "potential prognostic unfavorable (1.73e-4)" "unprognostic (6.98e-2)" "unprognostic (3.57e-1)" "unprognostic (5.18e-2)" "unprognostic (1.33e-1)" "unprognostic (5.44e-2)" "unprognostic (3.10e-2)" "unprognostic (1.50e-1)" "unprognostic (1.23e-1)" "unprognostic (4.02e-1)" ADAM17 "CD156B, cSVP, TACE" ENSG00000151694 "ADAM metallopeptidase domain 17" P78536 2 9488486-9556732 "CD markers, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Notch signaling pathway" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "monocytes: 418.7;Neutrophils: 898.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010738, HPA051575" Approved Approved Cytosol NA NA 470000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 30: White matter - Myelination" "Cluster 7: Liver cancer - Metabolism" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 23 Cytosol "HPA010738: , HPA051575: " "unprognostic (4.40e-3)" "unprognostic (1.03e-1)" "unprognostic (1.22e-1)" "unprognostic (3.29e-2)" "unprognostic (2.26e-1)" "unprognostic (1.11e-1)" "unprognostic (7.15e-2)" "unprognostic (5.00e-2)" "unprognostic (8.72e-3)" "unprognostic (2.47e-1)" "potential prognostic favorable (2.98e-5)" "unprognostic (5.49e-2)" "unprognostic (4.94e-2)" "potential prognostic unfavorable (6.27e-4)" "unprognostic (2.49e-2)" "unprognostic (4.73e-2)" "unprognostic (2.51e-2)" "unprognostic (1.95e-1)" "unprognostic (1.76e-1)" "unprognostic (1.88e-1)" "unprognostic (2.79e-2)" "unprognostic (4.49e-3)" "potential prognostic unfavorable (5.32e-7)" "unprognostic (1.24e-1)" "unprognostic (1.47e-1)" "unprognostic (2.51e-1)" "unprognostic (9.03e-2)" "unprognostic (3.03e-1)" "unprognostic (1.25e-1)" "unprognostic (2.31e-2)" "unprognostic (1.75e-2)" ADAM18 "ADAM27, tMDCIII" ENSG00000168619 "ADAM metallopeptidase domain 18" Q9Y3Q7 8 39584489-39730065 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 74 "testis: 8.7" "Cell type enriched" "Detected in some" 4 "Late primary spermatocytes: 201.9" "Low cell type specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" "Intracellular and membrane" "Developmental protein" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" ADAM19 MLTNB ENSG00000135074 "ADAM metallopeptidase domain 19" Q9H013 5 157395534-157575775 "Plasma proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "B-cells: 258.4;cDC: 132.9;Cone photoreceptor cells: 374.7;Extravillous trophoblasts: 212.1;Fibro-adipogenic progenitors: 126.5;Lymphatic endothelial cells: 125.0;Neutrophils: 369.6;pDCs: 276.1;Plasma cells: 215.7;Retinal bipolar cells: 233.8;Rod photoreceptor cells: 253.3;Smooth muscle cells: 192.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 128.7;eosinophil: 140.1;memory B-cell: 51.0;naive B-cell: 53.7;neutrophil: 70.8;plasmacytoid DC: 66.9" "Group enriched" "Detected in many" 5 "B-cells: 53.7;dendritic cells: 66.9;granulocytes: 140.1" "Low cancer specificity" "Detected in many" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" HPA055537 Approved Vesicles NA NA 14000 "Cluster 41: Basophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 37: Neurons - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 6 Vesicles "HPA055537: " "unprognostic (1.09e-1)" "unprognostic (3.83e-1)" "unprognostic (2.08e-1)" "unprognostic (5.09e-2)" "unprognostic (9.69e-2)" "unprognostic (9.72e-3)" "unprognostic (7.92e-3)" "unprognostic (2.41e-2)" "unprognostic (3.40e-1)" "unprognostic (4.17e-2)" "unprognostic (1.47e-3)" "unprognostic (1.30e-1)" "potential prognostic unfavorable (7.10e-5)" "unprognostic (7.44e-3)" "unprognostic (1.20e-1)" "unprognostic (2.77e-2)" "unprognostic (1.12e-3)" "unprognostic (8.81e-3)" "unprognostic (3.86e-3)" "unprognostic (3.75e-2)" "unprognostic (1.18e-1)" "unprognostic (1.17e-1)" "unprognostic (6.66e-3)" "unprognostic (2.59e-1)" "unprognostic (1.29e-1)" "unprognostic (1.01e-1)" "unprognostic (1.20e-1)" "unprognostic (5.70e-2)" "unprognostic (1.25e-1)" "unprognostic (9.31e-2)" "unprognostic (1.41e-1)" ADAM2 "CT15, FTNB, PH-30b, PH30" ENSG00000104755 "ADAM metallopeptidase domain 2" Q99965 8 39743735-39838227 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 357 "testis: 35.6" "Cell type enriched" "Detected in some" 4 "Late primary spermatocytes: 139.8" "Cell type enhanced" "Detected in some" "hippocampal CA1-3: 4.2;medium spiny neuron: 3.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "CAB022390, HPA024621, HPA026581" Enhanced NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 5: Rhabdoid - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" "CAB022390: , HPA024621: , HPA026581: " ADAM20 ENSG00000134007 "ADAM metallopeptidase domain 20" O43506 14 70522358-70535015 "Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 12 "testis: 4.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" HPA059377 Enhanced NA NA "Cluster 67: Testis - Mixed function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" "HPA059377: " "unprognostic (1.46e-2)" "unprognostic (1.17e-3)" ADAM21 ADAM31 ENSG00000139985 "ADAM metallopeptidase domain 21" Q9UKJ8 14 70417107-70460427 "Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "testis: 8.1" "Cell type enhanced" "Detected in many" "Adipocytes: 56.4;Cardiomyocytes: 34.7;Early spermatids: 96.2;Late primary spermatocytes: 53.2;Late spermatids: 224.6;Myonuclei: 33.2" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA059016 Uncertain NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 89: Adipocytes - Lipid metabolism" 24 "HPA059016: " "unprognostic (9.34e-2)" "unprognostic (3.49e-2)" ADAM22 MDC2 ENSG00000008277 "ADAM metallopeptidase domain 22" Q9P0K1 7 87934143-88202889 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" Receptor "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 48.2" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 181.2;Bergmann glia: 488.3;Brain excitatory neurons: 479.1;Brain inhibitory neurons: 289.1;Corticotrophs: 225.9;Oligodendrocyte progenitor cells: 281.1;Other brain neurons: 255.8;Renal connecting tubule cells: 211.2;Retinal amacrine cells: 276.7;Retinal ganglion cells: 270.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 9.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Neuroblastoma: 29.5" "Adrenal gland - Adrenal cortex cells, Skeletal muscle - Fibroblasts, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050325, CAB079064" Supported Approved "Cell Junctions" NA NA 85000 "Cluster 27: Cerebellum - Synaptic function" "Cluster 35: Non-specific - DNA binding" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 6 "Cell Junctions" "CAB079064: , HPA050325: " "potential prognostic favorable (9.91e-4)" "unprognostic (5.32e-2)" "unprognostic (2.34e-3)" "unprognostic (1.69e-3)" "unprognostic (3.81e-1)" "potential prognostic unfavorable (3.56e-4)" "unprognostic (2.26e-1)" "potential prognostic favorable (6.83e-5)" "unprognostic (2.16e-2)" "potential prognostic favorable (7.75e-8)" "unprognostic (1.76e-3)" "unprognostic (3.56e-3)" "unprognostic (3.69e-1)" "unprognostic (1.94e-1)" "unprognostic (2.01e-1)" "unprognostic (1.52e-1)" "unprognostic (6.66e-3)" "unprognostic (7.52e-2)" "unprognostic (1.49e-1)" "unprognostic (7.95e-2)" "unprognostic (1.53e-2)" "unprognostic (2.75e-1)" "unprognostic (6.73e-2)" "unprognostic (1.02e-1)" "potential prognostic unfavorable (3.04e-4)" ADAM23 MDC3 ENSG00000114948 "ADAM metallopeptidase domain 23" O75077 2 206443532-206621127 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 31.5;parathyroid gland: 77.8" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 344.4;Brain inhibitory neurons: 435.1;Cardiomyocytes: 167.4;Oligodendrocyte progenitor cells: 173.2;Other brain neurons: 245.7;Retinal amacrine cells: 171.4;Retinal bipolar cells: 294.6;Retinal ganglion cells: 502.2;Schwann cells: 198.2;Thymic myoid cells: 172.7;Thyrotrophs: 126.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Lung Squamous Cell Carcinoma (TCGA): 58.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 16 "memory CD4 T-cell: 2.1" "Lineage enriched" "Detected in single" 16 "T-cells: 2.1" "Cancer enhanced" "Detected in many" "Myeloma: 47.8" "Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Lung - Fibroblasts_2, Pituitary gland - Thyrotropes, Stomach - Fibroblasts, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012130, CAB033276" Approved Approved "Nucleoplasm,Plasma membrane" "Secreted in brain" "Cell adhesion" NA NA 25000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 7: Liver cancer - Metabolism" "Cluster 35: Neurons - Synaptic function & neurogenesis" 1 "Nucleoplasm, Plasma membrane" "CAB033276: , HPA012130: " "unprognostic (5.31e-2)" "unprognostic (7.03e-2)" "unprognostic (1.88e-1)" "unprognostic (1.69e-1)" "unprognostic (5.20e-2)" "unprognostic (2.96e-1)" "unprognostic (1.28e-1)" "unprognostic (1.21e-2)" "unprognostic (1.37e-2)" "unprognostic (1.96e-2)" "potential prognostic unfavorable (1.46e-5)" "unprognostic (6.02e-2)" "unprognostic (1.52e-1)" "unprognostic (4.70e-2)" "unprognostic (1.12e-1)" "unprognostic (1.19e-2)" "unprognostic (1.49e-2)" "unprognostic (5.37e-2)" "unprognostic (1.88e-1)" "unprognostic (3.01e-1)" "unprognostic (1.13e-2)" "unprognostic (7.77e-2)" "unprognostic (8.27e-3)" "unprognostic (3.72e-2)" "unprognostic (1.35e-1)" ADAM28 "ADAM23, eMDCII, MDC-Lm, MDC-Ls" ENSG00000042980 "ADAM metallopeptidase domain 28" Q9UKQ2 8 24294069-24359014 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "epididymis: 336.5;stomach 1: 103.8" "Cell type enhanced" "Detected in many" "B-cells: 767.0;cDC: 219.8;Conjunctival goblet cells: 336.9;Epididymal principal cells: 592.4;Foveolar cells: 358.7;Hematopoietic stem cells: 215.9;Macrophages: 243.7;Microglia: 1136.4;Mucous neck cells: 377.1;Pituitary stem cells: 761.8;Podocytes: 221.4;Respiratory basal cells: 223.9;Respiratory secretory cells: 213.0" "Cell type enriched" "Detected in many" 40 "central nervous system macrophage: 1395.1" "Cancer enhanced" "Detected in all" "Pancreatic Adenocarcinoma (TCGA): 34.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 72.0;naive B-cell: 87.4" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "pancreatic cancer: 9.9" "Adrenal gland - Macrophages, Spleen - B-cells (Spleen), Stomach - Gastric mucous cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA074034 Enhanced Approved "Plasma membrane,Mitochondria" "Secreted to blood" Enzyme NA NA 3720000 "Cluster 32: Basophils - Transcription" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 1 "Plasma membrane" Mitochondria "HPA074034: " "unprognostic (2.46e-1)" "unprognostic (5.80e-2)" "unprognostic (7.96e-2)" "unprognostic (8.55e-2)" "unprognostic (1.91e-2)" "unprognostic (2.81e-2)" "unprognostic (1.77e-1)" "unprognostic (4.38e-2)" "unprognostic (2.88e-2)" "unprognostic (3.49e-1)" "unprognostic (9.03e-2)" "unprognostic (2.28e-2)" "unprognostic (2.14e-2)" "unprognostic (7.99e-2)" "unprognostic (6.11e-2)" "unprognostic (2.10e-1)" "unprognostic (1.42e-1)" "unprognostic (2.45e-1)" "unprognostic (1.11e-1)" "unprognostic (1.12e-1)" "unprognostic (6.00e-2)" "unprognostic (1.19e-2)" "unprognostic (4.70e-2)" "unprognostic (6.13e-2)" "unprognostic (6.88e-2)" "unprognostic (9.57e-2)" "unprognostic (2.45e-1)" "unprognostic (9.09e-2)" "unprognostic (7.20e-2)" "unprognostic (1.21e-1)" "unprognostic (8.78e-3)" ADAM29 "CT73, svph1" ENSG00000168594 "ADAM metallopeptidase domain 29" Q9UKF5 4 174829668-174978180 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 78 "testis: 38.4" "Group enriched" "Detected in some" 37 "Early spermatids: 500.5;Late primary spermatocytes: 273.1;Late spermatids: 438.8" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Region enriched" "Detected in single" 4 "hypothalamus: 1.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Intracellular and membrane" "No annotated function" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" "unprognostic (5.06e-1)" ADAM30 svph4 ENSG00000134249 "ADAM metallopeptidase domain 30" Q9UKF2 1 119893533-119896515 "Plasma proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 243 "testis: 24.2" "Group enriched" "Detected in some" 12 "Early spermatids: 67.3;Late primary spermatocytes: 148.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA026080 Uncertain Approved "Mid piece" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 1 "Mid piece" "HPA026080: " ADAM32 ENSG00000197140 "ADAM metallopeptidase domain 32" Q8TC27 8 39106990-39284917 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "testis: 26.5" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 31.9;Brain inhibitory neurons: 26.4;Early spermatids: 168.5;Ependymal cells: 40.8;Late primary spermatocytes: 270.8;Late spermatids: 57.4;Other brain neurons: 30.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA044156 Enhanced Supported "Principal piece" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 109: Neurons - Neuronal signaling" 1 "Principal piece" "HPA044156: " "unprognostic (4.97e-2)" "unprognostic (4.04e-1)" "unprognostic (1.06e-2)" "unprognostic (1.66e-2)" "unprognostic (6.18e-2)" "unprognostic (8.71e-2)" "unprognostic (1.45e-1)" "unprognostic (2.40e-1)" ADAM33 "C20orf153, dJ964F7.1, DKFZp434K0521" ENSG00000149451 "ADAM metallopeptidase domain 33" Q9BZ11 20 3667965-3682246 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" Asthma "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 121.2" "Cell type enhanced" "Detected in some" "Bergmann glia: 63.4;Decidual stromal cells: 32.5;Endometrial stromal cells: 46.1;Fibro-adipogenic progenitors: 125.1;Fibroblasts: 59.8;Hepatic stellate cells: 38.7;Leydig cells: 55.6;Oligodendrocytes: 33.7;Pericytes: 34.2;Sertoli cells: 103.2;Smooth muscle cells: 68.4;Vascular smooth muscle cells: 28.7" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 152.3;fibroblast: 143.9;pericyte: 125.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "testis cancer: 12.9" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Smooth muscle cells, Breast - Fibroblasts, Colon - Enteric glia cells, Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Region enhanced" "Detected in single" "cerebral cortex: 1.0" "Low region specificity" "Detected in all" "HPA067152, HPA071758" Approved Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 49: Hindbrain - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" "Plasma membrane" "Nuclear speckles" "HPA067152: , HPA071758: " "unprognostic (7.14e-2)" "unprognostic (3.04e-1)" "unprognostic (6.49e-2)" "unprognostic (6.01e-2)" "unprognostic (3.14e-2)" "unprognostic (5.64e-2)" "unprognostic (2.71e-2)" "potential prognostic unfavorable (5.22e-5)" "unprognostic (2.17e-3)" "unprognostic (8.11e-2)" "potential prognostic favorable (5.84e-4)" "unprognostic (8.63e-3)" "unprognostic (1.66e-1)" "unprognostic (6.89e-2)" "unprognostic (1.41e-1)" "unprognostic (6.96e-2)" "unprognostic (3.43e-2)" "unprognostic (5.85e-2)" "unprognostic (1.98e-1)" "unprognostic (1.05e-1)" "unprognostic (2.93e-2)" "unprognostic (7.76e-2)" "unprognostic (1.73e-2)" "unprognostic (2.93e-1)" "unprognostic (2.58e-2)" ADAM7 "EAPI, GP-83" ENSG00000069206 "ADAM metallopeptidase domain 7" Q9H2U9 8 24440930-24526970 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 237 "epididymis: 3519.1" "Cell type enriched" "Detected in some" 7 "Epididymal principal cells: 3360.0" "Cell type enhanced" "Detected in many" "lower rhombic lip: 10.7;mammillary body: 16.6" "Cancer enhanced" "Detected in some" "Kidney Renal Papillary Cell Carcinoma (TCGA): 1.7;Prostate Adenocarcinoma (TCGA): 1.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 22 "prostate cancer: 2.5" "Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA008879 Enhanced "Intracellular and membrane" "No annotated function" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" "HPA008879: " "potential prognostic unfavorable (5.26e-7)" "potential prognostic favorable (2.58e-4)" ADAM8 "CD156, CD156A, MS2" ENSG00000151651 "ADAM metallopeptidase domain 8" P78325 10 133262420-133276868 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 64.8;lymphoid tissue: 46.8" "Cell type enhanced" "Detected in many" "cDC: 76.7;Extravillous trophoblasts: 136.8;Mast cells: 46.8;Migrating cytotrophoblasts: 37.8;monocytes: 36.8;Neutrophil progenitors: 44.4;Neutrophils: 325.5;NK-cells: 54.4;Urothelial cells: 39.2" "Cell type enriched" "Detected in many" 7 "leukocyte: 57.8" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 44.4" "Group enriched" "Detected in many" 5 "basophil: 107.8;eosinophil: 259.4;neutrophil: 139.8" "Lineage enriched" "Detected in all" 7 "granulocytes: 259.4" "Cancer enhanced" "Detected in many" "pancreatic cancer: 53.8" "Adipose visceral - Neutrophils, Breast - T-cells, Heart muscle - Neutrophils, Spleen - Neutrophils_2, Thyroid gland - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA064637 Approved "Intracellular and membrane" Enzyme NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 4 "HPA064637: " "unprognostic (2.31e-1)" "unprognostic (1.16e-1)" "unprognostic (1.49e-3)" "unprognostic (4.25e-3)" "unprognostic (1.94e-2)" "unprognostic (2.45e-1)" "unprognostic (8.06e-3)" "unprognostic (1.08e-1)" "unprognostic (6.14e-2)" "unprognostic (5.25e-2)" "potential prognostic unfavorable (3.37e-8)" "unprognostic (3.28e-2)" "unprognostic (7.71e-2)" "unprognostic (4.30e-2)" "unprognostic (4.33e-2)" "unprognostic (1.21e-2)" "unprognostic (1.90e-2)" "unprognostic (2.20e-2)" "unprognostic (1.53e-1)" "unprognostic (3.85e-3)" "unprognostic (1.65e-1)" "unprognostic (3.84e-2)" "unprognostic (2.91e-3)" "unprognostic (1.70e-1)" "unprognostic (2.36e-3)" "unprognostic (1.32e-1)" "unprognostic (1.39e-2)" "unprognostic (2.86e-1)" "unprognostic (3.96e-2)" "unprognostic (1.80e-1)" "unprognostic (3.25e-2)" ADAM9 "CORD9, KIAA0021, MCMP, MDC9, Mltng" ENSG00000168615 "ADAM metallopeptidase domain 9" Q13443 8 38996754-39105445 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Cone-rod dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 290.0;Endometrial luminal cells: 256.0;Urothelial cells: 252.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 4.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004000 Approved "Endoplasmic reticulum,Vesicles" "Secreted - unknown location" Enzyme NA NA 390000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 51: Secretory epithelial cells - Mixed function" 38 Vesicles "Endoplasmic reticulum" "HPA004000: " "unprognostic (1.30e-1)" "unprognostic (3.07e-3)" "unprognostic (5.09e-1)" "unprognostic (2.09e-1)" "potential prognostic favorable (5.47e-4)" "unprognostic (8.09e-2)" "unprognostic (3.71e-1)" "unprognostic (9.79e-2)" "unprognostic (2.72e-1)" "unprognostic (8.59e-2)" "potential prognostic favorable (3.96e-4)" "unprognostic (2.15e-1)" "unprognostic (3.82e-2)" "potential prognostic unfavorable (8.27e-4)" "unprognostic (1.82e-2)" "unprognostic (9.55e-3)" "unprognostic (9.08e-3)" "unprognostic (1.12e-1)" "unprognostic (1.17e-1)" "unprognostic (2.34e-2)" "unprognostic (3.15e-3)" "potential prognostic unfavorable (2.33e-5)" "unprognostic (4.76e-1)" "unprognostic (1.39e-1)" "unprognostic (1.10e-1)" "unprognostic (5.75e-2)" "unprognostic (1.19e-1)" "unprognostic (2.02e-1)" "unprognostic (2.48e-1)" "unprognostic (1.70e-1)" "unprognostic (4.45e-2)" ADAMDEC1 M12.219 ENSG00000134028 "ADAM like decysin 1" O15204 8 24384285-24406013 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "intestine: 400.1" "Cell type enhanced" "Detected in some" "B-cells: 10.0;cDC: 13.1;Macrophages: 55.2;monocytes: 18.1" "Cell type enriched" "Detected in single" 4 "mammillary body: 2.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "eosinophil: 1.9" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in single" "lymphoma: 1.1" "Adipose visceral - Macrophages, Minor Salivary Gland - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Secreted in other tissues" Enzyme NA NA 14000000 "Cluster 77: Intestine - Digestion" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" "unprognostic (6.51e-2)" "unprognostic (1.49e-2)" "unprognostic (4.64e-1)" "unprognostic (9.21e-3)" "unprognostic (4.76e-2)" "unprognostic (3.35e-2)" "unprognostic (1.69e-2)" "unprognostic (2.26e-2)" "unprognostic (2.72e-3)" "unprognostic (2.56e-1)" "unprognostic (1.15e-1)" "unprognostic (3.76e-2)" "unprognostic (2.27e-1)" "unprognostic (1.60e-1)" "unprognostic (1.30e-1)" "unprognostic (2.38e-1)" "unprognostic (1.27e-1)" "unprognostic (1.64e-1)" "unprognostic (1.23e-1)" "unprognostic (9.43e-3)" "unprognostic (3.45e-1)" "unprognostic (2.32e-1)" "unprognostic (2.36e-1)" "unprognostic (8.19e-2)" "unprognostic (8.67e-3)" "unprognostic (2.23e-1)" "unprognostic (3.83e-2)" "unprognostic (1.60e-1)" "unprognostic (5.47e-3)" "unprognostic (5.31e-2)" "unprognostic (8.14e-2)" ADAMTS1 "C3-C5, KIAA1346, METH1" ENSG00000154734 "ADAM metallopeptidase with thrombospondin type 1 motif 1" Q9UHI8 21 26835755-26845409 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Heparin-binding, Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 367.9" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 266.5;Endometrial luminal cells: 233.9;Endometrial stromal cells: 235.4;Extravillous trophoblasts: 339.6;Fibroblasts: 291.2;Migrating cytotrophoblasts: 187.0;Ovarian stromal cells: 216.7;Pericytes: 699.6;Smooth muscle cells: 356.9;Vascular endothelial cells: 389.2;Vascular smooth muscle cells: 929.1" "Group enriched" "Detected in many" 6 "endothelial cell: 196.7;vascular associated smooth muscle cell: 457.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "gdT-cell: 4.5;NK-cell: 6.6" "Group enriched" "Detected in many" 56 "NK-cells: 6.6;T-cells: 4.5" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells, Minor Salivary Gland - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "spinal cord: 41.6" "CAB016394, HPA031498" Approved Uncertain "Plasma membrane" "Secreted to extracellular matrix" Enzyme NA NA 2300000 "Cluster 15: NK-cells - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 11: White matter - Signal transduction" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 103: Non-specific - Basic cellular processes" 24 "Plasma membrane" "CAB016394: , HPA031498: " "unprognostic (9.64e-2)" "unprognostic (1.84e-1)" "unprognostic (1.84e-2)" "unprognostic (1.91e-1)" "unprognostic (3.18e-1)" "unprognostic (1.79e-2)" "unprognostic (4.37e-2)" "unprognostic (1.88e-3)" "potential prognostic unfavorable (1.02e-4)" "unprognostic (3.27e-2)" "unprognostic (6.37e-2)" "unprognostic (6.30e-3)" "unprognostic (6.85e-2)" "unprognostic (1.18e-1)" "unprognostic (1.43e-3)" "unprognostic (4.15e-2)" "unprognostic (1.42e-1)" "unprognostic (1.25e-1)" "unprognostic (3.40e-1)" "unprognostic (2.76e-2)" "unprognostic (1.48e-1)" "unprognostic (1.64e-1)" "unprognostic (5.78e-3)" "unprognostic (4.62e-2)" "unprognostic (5.00e-2)" "unprognostic (1.01e-2)" "unprognostic (1.54e-1)" "unprognostic (3.70e-3)" "unprognostic (1.07e-1)" "unprognostic (7.81e-3)" "unprognostic (1.43e-1)" ADAMTS10 ADAM-TS10 ENSG00000142303 "ADAM metallopeptidase with thrombospondin type 1 motif 10" Q9H324 19 8580240-8610735 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 55.6;Fibro-adipogenic progenitors: 41.8;Hepatic stellate cells: 45.2;Microglia: 69.4;Myosatellite cells: 185.6;Pericytes: 37.3;Vascular smooth muscle cells: 44.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 7.5" "Minor Salivary Gland - Endothelial cells, Stomach - Fibroblasts" "Region enriched" "Detected in many" 5 "cerebellum: 8.8" "Low region specificity" "Detected in all" HPA040223 Uncertain "Secreted to extracellular matrix" Enzyme NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 22: Non-specific - Basic cellular functions" "HPA040223: " "unprognostic (2.85e-1)" "unprognostic (1.66e-1)" "unprognostic (8.93e-3)" "unprognostic (8.51e-3)" "unprognostic (1.92e-1)" "unprognostic (5.22e-2)" "unprognostic (1.12e-1)" "potential prognostic unfavorable (4.90e-5)" "unprognostic (5.19e-2)" "unprognostic (2.42e-1)" "unprognostic (1.84e-2)" "potential prognostic favorable (9.90e-4)" "unprognostic (2.84e-1)" "unprognostic (2.18e-1)" "unprognostic (4.65e-2)" "unprognostic (5.18e-2)" "unprognostic (2.28e-1)" "unprognostic (2.39e-1)" "unprognostic (5.88e-3)" "unprognostic (1.86e-1)" "unprognostic (2.71e-2)" "unprognostic (7.22e-3)" "unprognostic (3.79e-3)" "unprognostic (2.40e-1)" "unprognostic (7.67e-2)" "unprognostic (1.12e-1)" ADAMTS12 ENSG00000151388 "ADAM metallopeptidase with thrombospondin type 1 motif 12" P58397 5 33523535-33892019 "Plasma proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 288.8;Adrenal cortex cells: 148.8;Endometrial stromal cells: 130.3;Fibro-adipogenic progenitors: 193.5;Fibroblasts: 106.4;Hepatic stellate cells: 129.1;Leydig cells: 179.0;Pericytes: 183.1;Peritubular myoid cells: 172.7" "Cell type enriched" "Detected in many" 6 "fibroblast: 507.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 70.1;testis cancer: 34.0" "Kidney - Fibroblasts, Prostate - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA035973, HPA075079" Uncertain Approved Nucleoli,Mitochondria "Secreted to extracellular matrix" Enzyme NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 21: Non-specific - Metabolism" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 89: Adipocytes - Lipid metabolism" 3 Nucleoli Mitochondria "HPA035973: , HPA075079: " "unprognostic (1.37e-1)" "unprognostic (1.11e-2)" "unprognostic (7.13e-2)" "unprognostic (1.79e-3)" "unprognostic (4.21e-2)" "unprognostic (9.23e-2)" "unprognostic (9.55e-2)" "unprognostic (1.55e-1)" "unprognostic (2.17e-1)" "unprognostic (5.04e-2)" "unprognostic (1.02e-1)" "unprognostic (3.44e-2)" "unprognostic (1.02e-2)" "unprognostic (2.07e-3)" "unprognostic (7.32e-2)" "unprognostic (2.07e-1)" "unprognostic (4.03e-3)" "potential prognostic unfavorable (1.51e-7)" "unprognostic (1.17e-2)" "unprognostic (1.74e-1)" "unprognostic (3.22e-1)" "unprognostic (3.06e-2)" "unprognostic (3.37e-2)" "unprognostic (1.62e-3)" "unprognostic (1.52e-1)" "unprognostic (2.31e-2)" "unprognostic (1.83e-2)" ADAMTS13 "C9orf8, DKFZp434C2322, FLJ42993, MGC118899, MGC118900, TTP, vWF-CP, VWFCP" ENSG00000160323 "ADAM metallopeptidase with thrombospondin type 1 motif 13" Q76LX8 9 133414358-133459402 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Metalloprotease, Protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 62.5" "Cell type enhanced" "Detected in some" "Astrocytes: 19.6;Bergmann glia: 12.0;Brain excitatory neurons: 12.2;Brain inhibitory neurons: 13.5;Distal convoluted tubule cells: 9.3;Early spermatids: 7.4;Ependymal cells: 14.2;Hepatic stellate cells: 6.5;Loop of henle epithelial cells: 9.0;Oligodendrocyte progenitor cells: 5.8;Oligodendrocytes: 8.4;Other brain neurons: 9.4;Papillary tip epithelial cells: 6.7;Podocytes: 6.5;Proximal tubule cells: 10.7;Renal collecting duct intercalated cells: 6.8;Renal collecting duct principal cells: 10.1;Renal connecting tubule cells: 10.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatic stellate cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA042014, HPA042844, HPA052077" Approved Uncertain Vesicles "Secreted to blood" "Blood coagulation" NA NA 1300000000 160000000 "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 37: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 102: Non-specific - Mixed function" 1 Vesicles "HPA042014: , HPA042844: , HPA052077: " "unprognostic (1.60e-1)" "unprognostic (5.66e-2)" "unprognostic (9.63e-2)" "unprognostic (2.89e-1)" "unprognostic (2.36e-1)" "unprognostic (1.81e-1)" "potential prognostic favorable (7.15e-4)" "unprognostic (2.38e-2)" "unprognostic (1.20e-1)" "unprognostic (5.01e-2)" "unprognostic (2.03e-1)" "unprognostic (5.43e-2)" "unprognostic (1.37e-1)" "unprognostic (3.55e-1)" "unprognostic (6.25e-3)" "unprognostic (1.81e-1)" "unprognostic (6.16e-2)" "potential prognostic favorable (2.39e-4)" "unprognostic (2.75e-2)" "unprognostic (1.19e-1)" "unprognostic (5.03e-2)" "unprognostic (1.44e-1)" "unprognostic (1.73e-1)" "unprognostic (1.75e-1)" "unprognostic (3.04e-2)" "unprognostic (8.37e-2)" ADAMTS14 ENSG00000138316 "ADAM metallopeptidase with thrombospondin type 1 motif 14" Q8WXS8 10 70672506-70762441 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "gallbladder: 6.3;placenta: 7.1" "Cell type enhanced" "Detected in some" "Epididymal basal cells: 12.8;Esophageal apical cells: 7.2;Hepatic stellate cells: 6.5;Mast cells: 11.9;Megakaryocyte-Erythroid progenitors: 12.8;Myosatellite cells: 23.7;Ocular epithelial cells: 12.5;Oligodendrocytes: 28.8;Respiratory ciliated cells: 9.7" "Group enriched" "Detected in some" 7 "committed oligodendrocyte precursor: 24.1;oligodendrocyte: 24.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Mitotic cells (Minor salivary gland), Prostate - Fibroblasts, Skeletal muscle - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA079400 Approved "Golgi apparatus,Vesicles" "Secreted to extracellular matrix" Enzyme NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 11: White matter - Signal transduction" "Cluster 47: Leukemia - Hemostasis" "Cluster 108: Fibroblasts - ECM organization" "Golgi apparatus, Vesicles" "HPA079400: " "unprognostic (9.45e-2)" "unprognostic (1.27e-1)" "unprognostic (1.45e-1)" "unprognostic (1.66e-2)" "unprognostic (1.76e-2)" "unprognostic (1.06e-1)" "unprognostic (7.77e-3)" "unprognostic (1.34e-1)" "unprognostic (2.28e-1)" "unprognostic (1.15e-3)" "unprognostic (1.34e-1)" "unprognostic (2.34e-1)" "unprognostic (1.09e-1)" "potential prognostic unfavorable (1.63e-4)" "unprognostic (1.90e-1)" "unprognostic (2.36e-1)" "unprognostic (1.35e-2)" "unprognostic (2.30e-1)" "unprognostic (2.38e-2)" "unprognostic (8.62e-2)" "unprognostic (9.55e-2)" "unprognostic (7.42e-2)" "unprognostic (5.74e-2)" "unprognostic (7.55e-2)" "unprognostic (9.17e-2)" "potential prognostic unfavorable (7.77e-4)" ADAMTS15 ENSG00000166106 "ADAM metallopeptidase with thrombospondin type 1 motif 15" Q8TE58 11 130448645-130476645 "Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 23.8" "Cell type enhanced" "Detected in many" "Adipocytes: 56.6;Cardiomyocytes: 32.8;Decidual stromal cells: 49.3;Endometrial luminal cells: 22.2;Endometrial stromal cells: 37.0;Fibroblasts: 31.7;Foveolar cells: 60.1;Loop of henle epithelial cells: 37.7;Mesothelial cells: 41.9;Myosatellite cells: 47.6;Retinal amacrine cells: 35.9" "Group enriched" "Detected in many" 4 "fibroblast: 24.7;mammillary body: 6.5;vascular associated smooth muscle cell: 16.2" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 19.8" "Region enhanced" "Detected in many" "medulla oblongata: 8.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Adipocytes (Breast), Pituitary gland - Fibroblasts, Spleen - Fibroblasts_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA042867 Uncertain Approved Cytosol "Secreted to extracellular matrix" Enzyme NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 12: Non-specific - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 108: Fibroblasts - ECM organization" Cytosol "HPA042867: " "unprognostic (2.10e-1)" "unprognostic (2.15e-1)" "unprognostic (1.48e-1)" "unprognostic (4.25e-3)" "unprognostic (1.79e-1)" "unprognostic (8.32e-2)" "validated prognostic favorable (4.27e-4)" "validated prognostic favorable (3.18e-5)" "unprognostic (5.85e-3)" "unprognostic (6.56e-2)" "unprognostic (9.76e-2)" "unprognostic (1.58e-1)" "unprognostic (7.90e-2)" "unprognostic (8.03e-2)" "unprognostic (1.16e-1)" "unprognostic (6.54e-3)" "unprognostic (1.52e-2)" "unprognostic (3.03e-2)" "unprognostic (1.04e-2)" "unprognostic (3.26e-1)" "unprognostic (1.36e-2)" "unprognostic (3.12e-1)" "unprognostic (2.37e-1)" "unprognostic (2.73e-2)" "unprognostic (9.12e-3)" "unprognostic (1.09e-2)" "unprognostic (2.93e-1)" "unprognostic (1.61e-3)" ADAMTS16 ADAMTS16s ENSG00000145536 "ADAM metallopeptidase with thrombospondin type 1 motif 16" Q8TE57 5 5140330-5320304 "Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 7.8;ovary: 22.8" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 102.9;Distal convoluted tubule cells: 351.8;Fibro-adipogenic progenitors: 89.8;Loop of henle epithelial cells: 59.7;Ovarian stromal cells: 105.7;Proximal tubule cells: 55.3;Renal collecting duct principal cells: 69.2;Renal connecting tubule cells: 450.9;Retinal amacrine cells: 47.2" "Cell type enhanced" "Detected in many" "hippocampal dentate gyrus: 285.9;upper rhombic lip: 219.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Fibroblasts, Lung - Fibroblasts_2, Skeletal muscle - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA061013 Approved Vesicles "Secreted to extracellular matrix" Enzyme NA No "Cluster 75: Ovary - Mixed function" "Cluster 35: Non-specific - DNA binding" "Cluster 72: Neuronal - Signal transduction" "Cluster 94: Gonadal somatic cells - Mixed function" Vesicles "HPA061013: " "unprognostic (1.60e-1)" "unprognostic (1.39e-1)" "unprognostic (1.45e-1)" "unprognostic (1.65e-1)" "potential prognostic favorable (1.27e-4)" "unprognostic (1.98e-2)" "unprognostic (5.83e-3)" "unprognostic (3.66e-3)" "potential prognostic favorable (3.61e-6)" "unprognostic (1.18e-1)" "unprognostic (3.08e-1)" "unprognostic (5.16e-2)" "unprognostic (3.91e-2)" "unprognostic (5.06e-3)" "unprognostic (1.28e-1)" "unprognostic (3.04e-2)" "unprognostic (1.17e-1)" "unprognostic (1.39e-2)" "unprognostic (4.46e-2)" "unprognostic (5.85e-2)" "unprognostic (9.69e-2)" "potential prognostic unfavorable (8.93e-4)" "unprognostic (1.92e-1)" "unprognostic (1.81e-3)" ADAMTS17 "FLJ16363, FLJ32769" ENSG00000140470 "ADAM metallopeptidase with thrombospondin type 1 motif 17" Q8TE56 15 99971437-100342005 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Deafness, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 7.0;lymphoid tissue: 9.9" "Cell type enhanced" "Detected in many" "Astrocytes: 219.0;Distal convoluted tubule cells: 624.0;NK-cells: 235.2;Oligodendrocyte progenitor cells: 572.9;Pituicytes/FSCs: 275.0;Pituitary stem cells: 259.3;Retinal horizontal cells: 817.4" "Cell type enhanced" "Detected in all" "MGE interneuron: 306.0;oligodendrocyte precursor cell: 708.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 6.0" "Kidney - Ascending Loop of Henle cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA062487 Approved Nucleoplasm "Secreted to extracellular matrix" Enzyme NA NA "Cluster 70: Non-specific - Protein processing" "Cluster 23: Choroid plexus - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" Nucleoplasm "HPA062487: " "unprognostic (2.33e-1)" "unprognostic (3.65e-2)" "unprognostic (1.23e-2)" "unprognostic (3.49e-1)" "potential prognostic favorable (2.07e-5)" "unprognostic (1.88e-2)" "unprognostic (2.04e-2)" "unprognostic (1.07e-1)" "unprognostic (2.08e-2)" "unprognostic (1.72e-3)" "potential prognostic favorable (7.14e-4)" "unprognostic (4.75e-2)" "unprognostic (2.84e-2)" "unprognostic (1.57e-1)" "unprognostic (1.87e-1)" "unprognostic (2.90e-2)" "unprognostic (1.66e-1)" "unprognostic (1.58e-1)" ADAMTS18 ADAMTS21 ENSG00000140873 "ADAM metallopeptidase with thrombospondin type 1 motif 18" Q8TE60 16 77247813-77435034 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 13.8;placenta: 19.4" "Cell type enhanced" "Detected in many" "Bergmann glia: 58.7;Brain excitatory neurons: 84.7;Medullary thymic epithelial cells: 86.4;Müller glia: 163.6;Oligodendrocytes: 107.4;Pituicytes/FSCs: 47.7;Pituitary stem cells: 134.3;Renal collecting duct intercalated cells: 62.7;Retinal amacrine cells: 72.4;Rod photoreceptor cells: 56.5;Salivary acinar cells: 65.2;Thyrotrophs: 96.6;Tuft cells: 126.8" "Cell type enhanced" "Detected in many" "oligodendrocyte: 164.1;upper rhombic lip: 304.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "liver cancer: 2.6;testis cancer: 9.8" "Adipose visceral - Endothelial cells, Breast - Endothelial cells" "Region enriched" "Detected in single" 5 "cerebellum: 3.3" "Low region specificity" "Detected in all" HPA044326 Uncertain Approved "Midbody,Mitotic spindle" "Secreted to extracellular matrix" Enzyme Yes NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 25: Non-specific - Transcription" "Cluster 70: DU4475 - Unknown function" "Cluster 2: Cerebellar granular cells - Neuronal signaling" "Midbody, Mitotic spindle" "HPA044326: " "unprognostic (1.43e-1)" "unprognostic (2.24e-1)" "unprognostic (4.82e-2)" "unprognostic (6.05e-2)" "unprognostic (1.03e-1)" ADAMTS19 ENSG00000145808 "ADAM metallopeptidase with thrombospondin type 1 motif 19" 5 129460281-129738683 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "cervix: 9.5;endometrium 1: 9.2;smooth muscle: 5.5" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 393.6;Brain excitatory neurons: 103.7;Brain inhibitory neurons: 221.9;Cytotrophoblasts: 256.0;Endometrial stromal cells: 139.4;Myonuclei: 171.4;Podocytes: 1207.1" "Cell type enhanced" "Detected in many" "deep-layer near-projecting: 404.3" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 1.6;Uterine Corpus Endometrial Carcinoma (TCGA): 1.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Neuroblastoma: 7.7" "Adrenal gland - Adrenal medulla cells, Kidney - Podocytes, Prostate - Fibroblasts" "Region enriched" "Detected in single" 5 "olfactory bulb: 2.6" "Low region specificity" "Detected in all" "HPA056171, HPA058438" Uncertain Approved Vesicles,Midbody "Secreted to extracellular matrix" Yes NA "Cluster 75: Ovary - Mixed function" "Cluster 33: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 57: Podocytes - Glomerular filtration" "Vesicles, Midbody" "HPA056171: , HPA058438: " "unprognostic (3.26e-1)" "unprognostic (1.05e-3)" "unprognostic (7.99e-2)" "unprognostic (7.63e-2)" ADAMTS2 "ADAM-TS2, ADAMTS-3, hPCPNI, NPI, PCINP" ENSG00000087116 "ADAM metallopeptidase with thrombospondin type 1 motif 2" O95450 5 179110853-179345461 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 114.4;Endometrial stromal cells: 99.3;Fibro-adipogenic progenitors: 116.2;Fibroblasts: 97.9;Hepatic stellate cells: 606.8;Kupffer cells: 236.8;Lactotrophs: 107.0;Monocyte progenitors: 205.3;monocytes: 213.3;Pericytes: 83.3;Somatotrophs: 90.9;Thyrotrophs: 183.6" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 129.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Fibroblasts, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA028363, HPA028444" Uncertain Approved "Vesicles,Plasma membrane" "Secreted to extracellular matrix" Enzyme NA NA 6600000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 49: Hindbrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" "Plasma membrane" Vesicles "HPA028363: , HPA028444: " "unprognostic (9.63e-2)" "unprognostic (2.02e-1)" "unprognostic (2.19e-2)" "unprognostic (3.39e-3)" "unprognostic (1.93e-1)" "unprognostic (1.41e-1)" "unprognostic (8.74e-3)" "unprognostic (4.38e-2)" "unprognostic (1.21e-1)" "unprognostic (3.03e-2)" "unprognostic (1.09e-1)" "unprognostic (1.06e-1)" "unprognostic (4.32e-2)" "unprognostic (6.76e-2)" "unprognostic (2.06e-2)" "unprognostic (4.07e-2)" "unprognostic (7.01e-3)" "unprognostic (4.32e-2)" "unprognostic (1.41e-1)" "unprognostic (3.06e-3)" "unprognostic (4.87e-2)" "unprognostic (1.01e-1)" "unprognostic (4.65e-2)" "unprognostic (2.62e-1)" "unprognostic (1.77e-2)" "unprognostic (1.09e-2)" "unprognostic (7.47e-2)" "unprognostic (5.43e-3)" "unprognostic (1.79e-2)" "unprognostic (1.14e-3)" "unprognostic (1.79e-2)" ADAMTS20 GON-1 ENSG00000173157 "ADAM metallopeptidase with thrombospondin type 1 motif 20" P59510 12 43353866-43552203 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Extravillous trophoblasts: 50.3;Retinal bipolar cells: 84.7;Thymic myoid cells: 27.2" "Group enriched" "Detected in many" 6 "committed oligodendrocyte precursor: 52.2;lower rhombic lip: 192.9" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "medulla oblongata: 3.6;pons: 6.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 9.4" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027608, HPA027609" Uncertain Approved "Golgi apparatus,Microtubules,Mitotic spindle,Primary cilium,Basal body,Cytosol" "Secreted to extracellular matrix" Enzyme Yes NA "Cluster 49: Hindbrain - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "Golgi apparatus, Primary cilium" "Microtubules, Mitotic spindle, Basal body, Cytosol" "HPA027608: , HPA027609: " "potential prognostic favorable (1.94e-4)" "unprognostic (8.43e-2)" ADAMTS3 "ADAMTS-4, KIAA0366" ENSG00000156140 "ADAM metallopeptidase with thrombospondin type 1 motif 3" O15072 4 72280969-72569221 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Heparin-binding, Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 7.8" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 107.8;Cone photoreceptor cells: 362.3;Ependymal cells: 97.6;Epicardial cells: 325.2;Erythrocyte progenitors: 116.8;Leydig cells: 263.5;Megakaryocyte-Erythroid progenitors: 117.1;Mesothelial cells: 217.7;Renal connecting tubule cells: 133.7;Rod photoreceptor cells: 263.4" "Cell type enhanced" "Detected in many" "mammillary body: 176.8;medium spiny neuron: 287.7;upper-layer intratelencephalic: 200.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 20.4" "Adipose visceral - Mesothelial cells, Breast - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA021368, HPA021369" Uncertain Approved "Intermediate filaments" "Secreted to extracellular matrix" Enzyme NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 79: Photoreceptor cells - Phototransduction" 1 "Intermediate filaments" "HPA021368: , HPA021369: " "unprognostic (1.35e-1)" "unprognostic (7.60e-2)" "potential prognostic unfavorable (1.97e-5)" "unprognostic (2.44e-1)" "unprognostic (4.10e-3)" "unprognostic (2.42e-2)" "unprognostic (1.13e-1)" "unprognostic (4.02e-2)" "unprognostic (3.70e-1)" "unprognostic (1.43e-1)" ADAMTS4 "ADAMTS-2, ADMP-1, KIAA0688" ENSG00000158859 "ADAM metallopeptidase with thrombospondin type 1 motif 4" O75173 1 161184302-161199054 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 108.5;ovary: 84.8" "Cell type enhanced" "Detected in some" "Decidual stromal cells: 85.6;Fibroblasts: 96.6;Oligodendrocytes: 71.5;Ovarian stromal cells: 85.8;Pericytes: 498.2;Smooth muscle cells: 152.2;Vascular endothelial cells: 150.9;Vascular smooth muscle cells: 275.9" "Group enriched" "Detected in some" 7 "committed oligodendrocyte precursor: 27.6;oligodendrocyte: 95.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 10 "plasmacytoid DC: 4.4" "Lineage enriched" "Detected in single" 10 "dendritic cells: 4.4" "Cancer enhanced" "Detected in some" "Bone cancer: 8.1;skin cancer: 5.6" "Breast - Endothelial cells, Colon - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025876, HPA051296, HPA068374" Uncertain Supported "Nuclear speckles" "Secreted to extracellular matrix" Enzyme NA NA 60000 "Cluster 30: Non-specific - DNA binding" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 30: White matter - Myelination" "Cluster 69: Skin cancer - ECM organization" "Cluster 103: Non-specific - Basic cellular processes" 30 "Nuclear speckles" "CAB025876: , HPA051296: , HPA068374: " "unprognostic (9.36e-2)" "unprognostic (7.31e-2)" "unprognostic (3.10e-1)" "unprognostic (3.15e-3)" "unprognostic (3.71e-2)" "unprognostic (6.93e-2)" "unprognostic (7.30e-3)" "unprognostic (3.41e-1)" "unprognostic (1.04e-1)" "unprognostic (2.74e-1)" "unprognostic (1.45e-1)" "potential prognostic favorable (1.97e-4)" "potential prognostic unfavorable (6.01e-9)" "unprognostic (2.85e-1)" "unprognostic (1.81e-2)" "potential prognostic unfavorable (8.24e-4)" "unprognostic (4.54e-3)" "unprognostic (4.19e-2)" "unprognostic (1.86e-1)" "unprognostic (5.25e-2)" "unprognostic (1.90e-1)" "unprognostic (4.35e-2)" "unprognostic (6.11e-2)" "unprognostic (3.58e-1)" "unprognostic (7.82e-3)" "potential prognostic favorable (7.14e-4)" "unprognostic (1.13e-1)" "unprognostic (6.59e-2)" "unprognostic (1.19e-1)" "potential prognostic unfavorable (5.93e-4)" "unprognostic (1.15e-1)" ADAMTS5 "ADAMTS11, ADMP-2" ENSG00000154736 "ADAM metallopeptidase with thrombospondin type 1 motif 5" Q9UNA0 21 26917922-26967088 "Cancer-related genes, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 24.0;placenta: 24.5" "Cell type enhanced" "Detected in many" "Adipocytes: 115.2;Breast myoepithelial cells: 164.5;Decidual stromal cells: 91.5;Endometrial stromal cells: 118.8;Fibro-adipogenic progenitors: 224.1;Fibroblasts: 161.7;Leydig cells: 109.7;Lymphatic endothelial cells: 77.4;Myosatellite cells: 111.4;Ovarian stromal cells: 62.6;Pericytes: 90.2" "Cell type enhanced" "Detected in many" "LAMP5-LHX6 and Chandelier: 43.7;upper rhombic lip: 42.2" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 5.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Sarcoma: 6.8;thyroid cancer: 4.9" "Liver - Hepatic stellate cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA005661, CAB025996" Approved "Secreted to extracellular matrix" Enzyme NA NA 9200 "Cluster 75: Ovary - Mixed function" "Cluster 25: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" "CAB025996: , HPA005661: " "unprognostic (3.04e-1)" "unprognostic (1.61e-1)" "unprognostic (1.73e-1)" "unprognostic (1.05e-1)" "unprognostic (3.24e-1)" "unprognostic (1.01e-1)" "unprognostic (2.99e-3)" "unprognostic (2.33e-2)" "potential prognostic unfavorable (5.98e-4)" "unprognostic (8.23e-2)" "unprognostic (1.18e-2)" "unprognostic (4.52e-1)" "unprognostic (6.89e-2)" "unprognostic (1.11e-2)" "unprognostic (1.26e-1)" "unprognostic (1.88e-1)" "unprognostic (4.93e-2)" "unprognostic (1.41e-1)" "unprognostic (6.58e-3)" "unprognostic (1.72e-1)" "unprognostic (1.12e-3)" "unprognostic (2.71e-1)" ADAMTS6 ADAM-TS6 ENSG00000049192 "ADAM metallopeptidase with thrombospondin type 1 motif 6" Q9UKP5 5 65148738-65481920 "Cancer-related genes, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 1.8" "Cell type enhanced" "Detected in many" "B-cells: 83.6;Choroid plexus epithelial cells: 307.9;Cytotrophoblasts: 142.4;Fibro-adipogenic progenitors: 91.6;Leydig cells: 91.7;Lymphatic endothelial cells: 110.8;Oligodendrocyte progenitor cells: 185.0;Peritubular myoid cells: 100.8;Undifferentiated spermatogonia: 134.1;Vascular endothelial cells: 131.7" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 256.9;endothelial cell: 265.1;oligodendrocyte precursor cell: 235.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "memory B-cell: 2.1;naive B-cell: 1.3" "Lineage enhanced" "Detected in single" "B-cells: 2.1" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA043441 Enhanced "Secreted to extracellular matrix" Enzyme NA Yes "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 43: Hindbrain - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" "HPA043441: " "unprognostic (2.35e-2)" "unprognostic (6.93e-2)" "unprognostic (8.16e-3)" "unprognostic (4.77e-2)" "unprognostic (3.13e-2)" ADAMTS7 "ADAM-TS7, DKFZp434H204" ENSG00000136378 "ADAM metallopeptidase with thrombospondin type 1 motif 7" Q9UKP4 15 78759206-78811464 "Plasma proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 14.2;heart muscle: 28.7" "Cell type enhanced" "Detected in many" "Adipocytes: 11.8;Cardiomyocytes: 73.9;Endometrial stromal cells: 12.0;Epicardial cells: 20.5;Mast cells: 40.5;Myosatellite cells: 15.8;Schwann cells: 15.2" "Group enriched" "Detected in some" 4 "astrocyte: 5.4;Bergmann glia: 8.0;choroid plexus epithelial cell: 8.2;committed oligodendrocyte precursor: 3.5;fibroblast: 6.1;oligodendrocyte precursor cell: 9.9;pericyte: 13.6;vascular associated smooth muscle cell: 4.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 16.4" "Adipose subcutaneous - Adipose progenitor cells, Colon - Enteric glia cells, Minor Salivary Gland - Endothelial cells, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA045284, HPA048453" Uncertain Supported Vesicles "Secreted to extracellular matrix" Enzyme NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 49: HMC-1 - Innate immune response" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 37 Vesicles "HPA045284: , HPA048453: " "unprognostic (1.05e-1)" "unprognostic (2.05e-2)" "unprognostic (2.07e-1)" "unprognostic (1.66e-1)" "unprognostic (2.08e-1)" "unprognostic (1.74e-1)" "unprognostic (2.29e-1)" "unprognostic (1.15e-1)" "unprognostic (1.24e-1)" "unprognostic (4.47e-1)" "unprognostic (1.89e-3)" "unprognostic (4.73e-2)" "unprognostic (9.93e-2)" "unprognostic (6.68e-2)" "unprognostic (2.13e-2)" "unprognostic (8.18e-3)" "unprognostic (1.16e-2)" "unprognostic (8.72e-2)" "unprognostic (1.54e-1)" "unprognostic (3.31e-2)" "unprognostic (1.75e-2)" "unprognostic (5.14e-2)" "unprognostic (1.16e-1)" "unprognostic (9.55e-3)" "unprognostic (4.71e-3)" "unprognostic (3.47e-3)" "unprognostic (1.28e-1)" "unprognostic (6.54e-3)" "unprognostic (2.66e-1)" ADAMTS8 "ADAM-TS8, FLJ41712, METH2" ENSG00000134917 "ADAM metallopeptidase with thrombospondin type 1 motif 8" Q9UP79 11 130404923-130428609 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Heparin-binding, Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 33.2" "Cell type enhanced" "Detected in some" "Decidual stromal cells: 37.3;Endometrial glandular cells: 41.4;Endometrial luminal cells: 29.9;Endometrial stromal cells: 30.9;Epididymal basal cells: 30.2;Fibroblasts: 15.4;Myosatellite cells: 19.1;Pituicytes/FSCs: 18.0;Retinal amacrine cells: 14.5;Schwann cells: 17.8;Smooth muscle cells: 25.8;Vascular smooth muscle cells: 34.7" "Cell type enhanced" "Detected in many" "fibroblast: 55.0;hippocampal dentate gyrus: 37.3" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 4.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Adrenocortical cancer: 6.7" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA066349 Approved "Secreted to extracellular matrix" Enzyme NA NA 13000000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 51: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" "HPA066349: " "unprognostic (7.17e-2)" "unprognostic (9.65e-3)" "unprognostic (2.25e-1)" "unprognostic (1.83e-1)" "unprognostic (4.28e-3)" "unprognostic (6.25e-3)" "unprognostic (3.47e-2)" "unprognostic (1.09e-1)" "unprognostic (2.27e-1)" "unprognostic (1.53e-1)" "unprognostic (9.10e-2)" "unprognostic (1.88e-1)" "unprognostic (1.03e-2)" "unprognostic (2.54e-1)" "unprognostic (2.48e-3)" ADAMTS9 KIAA1312 ENSG00000163638 "ADAM metallopeptidase with thrombospondin type 1 motif 9" Q9P2N4 3 64515654-64688000 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "ER-Golgi transport, Protein transport, Transport" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 39.1" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 373.3;Endometrial stromal cells: 775.2;Epicardial cells: 891.5;Lymphatic endothelial cells: 525.3;Mesothelial cells: 619.0;Pericytes: 751.9;Podocytes: 1242.5;Vascular endothelial cells: 1365.5;Vascular smooth muscle cells: 774.0" "Cell type enhanced" "Detected in many" "astrocyte: 283.4;vascular associated smooth muscle cell: 140.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 45.5;testis cancer: 37.3" "Breast - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA028567, HPA028577, HPA028601" Approved Supported "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" Transport No NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 44: Non-specific - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "Endoplasmic reticulum" Vesicles "HPA028567: , HPA028577: , HPA028601: " "unprognostic (5.51e-2)" "unprognostic (3.97e-1)" "unprognostic (5.10e-2)" "unprognostic (8.00e-2)" "unprognostic (1.39e-1)" "unprognostic (1.19e-2)" "unprognostic (4.10e-1)" "unprognostic (1.53e-1)" "unprognostic (3.48e-2)" "unprognostic (1.16e-1)" "unprognostic (2.31e-3)" "unprognostic (1.56e-3)" "unprognostic (4.07e-2)" "unprognostic (3.87e-3)" "unprognostic (1.24e-1)" "unprognostic (2.70e-1)" "unprognostic (2.28e-2)" "unprognostic (1.34e-2)" "unprognostic (6.40e-2)" "unprognostic (1.99e-1)" "unprognostic (6.47e-2)" "unprognostic (9.33e-2)" "unprognostic (1.41e-2)" "unprognostic (5.01e-1)" "unprognostic (1.21e-1)" "unprognostic (2.21e-1)" "unprognostic (1.82e-1)" "unprognostic (3.21e-2)" "unprognostic (9.64e-2)" "unprognostic (7.02e-3)" "unprognostic (1.05e-1)" ADAMTSL1 "ADAMTSR1, C9orf94, FLJ35283" ENSG00000178031 "ADAMTS like 1" Q8N6G6 9 17906563-18910950 "Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 12.5" "Cell type enriched" "Detected in many" 5 "Bergmann glia: 3894.9" "Group enriched" "Detected in all" 4 "Bergmann glia: 3673.3;deep-layer corticothalamic and 6b: 1246.3" "Group enriched" "Detected in many" 10 "Kidney Chromophobe (TCGA): 21.7;Prostate Adenocarcinoma (TCGA): 7.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 15.5;Sarcoma: 18.9" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells, Breast - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblasts_2, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA057437, HPA074973" Uncertain Approved Vesicles "Secreted in other tissues" Enzyme NA NA 6000000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" Vesicles "HPA057437: , HPA074973: " "unprognostic (1.66e-1)" "unprognostic (2.08e-2)" "unprognostic (1.19e-1)" "unprognostic (2.09e-1)" "unprognostic (1.07e-1)" "unprognostic (1.72e-1)" "unprognostic (1.44e-2)" "unprognostic (4.18e-3)" "unprognostic (1.06e-1)" "unprognostic (2.83e-3)" "unprognostic (2.41e-2)" "potential prognostic favorable (1.74e-4)" "potential prognostic unfavorable (1.23e-5)" "unprognostic (8.09e-2)" "unprognostic (9.43e-2)" "unprognostic (7.19e-2)" "unprognostic (3.45e-2)" "unprognostic (7.73e-3)" "unprognostic (1.82e-1)" "unprognostic (1.38e-1)" ADAMTSL2 KIAA0605 ENSG00000197859 "ADAMTS like 2" Q86TH1 9 133532164-133575519 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 71.2;liver: 35.6" "Cell type enhanced" "Detected in many" "Corticotrophs: 21.7;Epididymal principal cells: 22.3;Fibro-adipogenic progenitors: 66.4;Fibroblasts: 27.9;Hepatic stellate cells: 135.6;Lactotrophs: 21.2;Leydig cells: 28.3;Microglia: 95.4;Pancreatic islet cells: 21.0" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 103.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 4.5" "Adrenal gland - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Spleen - Fibroblasts_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA045634, HPA053812" Approved Approved Vesicles "Secreted in other tissues" "No annotated function" NA NA 43000000 "Cluster 70: Non-specific - Protein processing" "Cluster 49: Hindbrain - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 105: Non-specific - Mixed function" Vesicles "HPA045634: , HPA053812: " "unprognostic (2.36e-1)" "unprognostic (1.81e-2)" "unprognostic (4.96e-2)" "potential prognostic unfavorable (9.20e-4)" "unprognostic (2.30e-2)" "unprognostic (1.01e-1)" "unprognostic (2.02e-1)" "unprognostic (2.67e-3)" "unprognostic (1.21e-1)" "unprognostic (6.74e-3)" "unprognostic (1.58e-3)" "potential prognostic favorable (3.28e-5)" "unprognostic (1.20e-1)" "unprognostic (7.70e-3)" "potential prognostic favorable (5.93e-5)" "unprognostic (8.18e-3)" "unprognostic (2.43e-1)" "potential prognostic unfavorable (9.13e-4)" "unprognostic (1.64e-1)" "unprognostic (1.38e-1)" "unprognostic (1.44e-1)" "unprognostic (5.28e-3)" "unprognostic (2.64e-1)" "unprognostic (5.49e-2)" "unprognostic (3.67e-2)" "unprognostic (2.53e-1)" "unprognostic (8.66e-2)" "unprognostic (1.58e-1)" "unprognostic (2.11e-1)" "unprognostic (1.72e-1)" "unprognostic (1.63e-1)" ADAMTSL3 "KIAA1233, punctin-2" ENSG00000156218 "ADAMTS like 3" P82987 15 83654088-84039842 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 17.9" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 235.1;Bergmann glia: 450.7;Choroid plexus epithelial cells: 496.3;Fibro-adipogenic progenitors: 700.3;Leydig cells: 601.3;Renal collecting duct intercalated cells: 254.6" "Cell type enhanced" "Detected in all" "Bergmann glia: 415.8;fibroblast: 424.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney cancer: 7.5" "Adrenal gland - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatocytes, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA034773, HPA034774" Uncertain Approved Vesicles "Secreted in other tissues" "No annotated function" NA NA 250000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 46: Brainstem - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 13 Vesicles "HPA034773: , HPA034774: " "unprognostic (2.68e-1)" "unprognostic (3.46e-1)" "unprognostic (3.52e-2)" "unprognostic (8.61e-2)" "unprognostic (1.80e-2)" "unprognostic (3.86e-3)" "potential prognostic favorable (1.21e-7)" "unprognostic (1.59e-2)" "unprognostic (4.36e-2)" "unprognostic (4.70e-2)" "potential prognostic favorable (1.77e-5)" "unprognostic (7.91e-2)" "unprognostic (1.64e-2)" "unprognostic (1.23e-1)" "unprognostic (7.63e-2)" "unprognostic (2.15e-1)" "unprognostic (2.06e-1)" "unprognostic (8.80e-3)" "unprognostic (4.22e-1)" "unprognostic (1.86e-2)" "unprognostic (8.22e-3)" "unprognostic (4.61e-1)" "unprognostic (8.51e-2)" ADAMTSL4 "DKFZP434K1772, TSRC1" ENSG00000143382 "ADAMTS like 4" Q6UY14 1 150549369-150560937 "Disease related genes, Human disease related genes, Predicted secreted proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 174.5;Epicardial cells: 345.7;Esophageal apical cells: 199.2;Migrating cytotrophoblasts: 119.4;Myonuclei: 85.5;Neutrophils: 63.3;Syncytiotrophoblasts: 104.9" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 7.0;choroid plexus epithelial cell: 12.5;ependymal cell: 7.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.3" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in all" "Bladder cancer: 39.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA006279 Approved Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" Other NA NA 26000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 10 "Plasma membrane, Cytosol" "HPA006279: " "unprognostic (4.08e-1)" "unprognostic (6.64e-2)" "unprognostic (7.18e-3)" "unprognostic (3.44e-2)" "unprognostic (1.99e-2)" "unprognostic (9.70e-2)" "unprognostic (4.30e-3)" "potential prognostic unfavorable (8.14e-6)" "unprognostic (1.47e-1)" "unprognostic (9.43e-2)" "unprognostic (4.78e-2)" "unprognostic (1.05e-2)" "unprognostic (2.59e-2)" "unprognostic (4.84e-1)" "unprognostic (7.03e-2)" "unprognostic (1.99e-1)" "unprognostic (3.08e-1)" "unprognostic (1.35e-3)" "unprognostic (1.48e-1)" "unprognostic (2.05e-2)" "unprognostic (1.64e-1)" "unprognostic (1.14e-2)" "unprognostic (2.54e-2)" "unprognostic (9.79e-2)" "unprognostic (3.97e-3)" "unprognostic (2.16e-3)" "unprognostic (2.25e-1)" "unprognostic (1.54e-1)" "unprognostic (5.19e-2)" "unprognostic (1.48e-2)" "unprognostic (2.30e-2)" ADAMTSL5 THSD6 ENSG00000185761 "ADAMTS like 5" 19 1505022-1513604 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 31.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 41.0;Choroid plexus epithelial cells: 10.8;Decidual stromal cells: 20.4;Enterocytes: 11.7;Esophageal apical cells: 14.3;Esophageal basal cells: 9.5;Esophageal suprabasal cells: 13.4;Leydig cells: 22.5;Myonuclei: 18.0;Peritubular myoid cells: 19.9" "Group enriched" "Detected in some" 5 "astrocyte: 4.0;choroid plexus epithelial cell: 12.9;pericyte: 9.0;vascular associated smooth muscle cell: 4.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Breast - Breast glandular cells, Kidney - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA044050 Approved "Golgi apparatus" "Secreted to extracellular matrix" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" "Golgi apparatus" "HPA044050: " "unprognostic (5.31e-2)" "unprognostic (1.47e-1)" "unprognostic (8.06e-2)" "unprognostic (3.46e-2)" "unprognostic (2.05e-1)" "unprognostic (2.34e-1)" "unprognostic (2.81e-1)" "unprognostic (1.87e-1)" "unprognostic (8.17e-2)" "unprognostic (2.75e-3)" "unprognostic (2.33e-2)" "unprognostic (9.01e-2)" "unprognostic (1.19e-3)" "unprognostic (1.66e-2)" "unprognostic (1.15e-1)" "unprognostic (8.80e-2)" "unprognostic (1.22e-3)" "unprognostic (5.99e-3)" "unprognostic (1.19e-1)" "unprognostic (4.61e-1)" "unprognostic (1.15e-2)" "unprognostic (2.47e-1)" "unprognostic (5.06e-2)" "unprognostic (2.22e-1)" "unprognostic (3.93e-1)" "unprognostic (1.82e-1)" ADAP1 "CENTA1, GCS1L" ENSG00000105963 "ArfGAP with dual PH domains 1" O75689 7 897900-955407 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 131.1" "Cell type enhanced" "Detected in many" "Colonocytes: 75.5;Enterocytes: 43.3;Foveolar cells: 47.1;Goblet cells: 39.6;monocytes: 42.2;Oligodendrocytes: 60.1;Oocytes: 285.5" "Cell type enhanced" "Detected in all" "oligodendrocyte: 84.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "colorectal cancer: 123.4;Gastric cancer: 101.4" "Adipose subcutaneous - Macrophages, Skeletal muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007033, HPA012049" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 12 "Plasma membrane, Cytosol" "HPA007033: , HPA012049: " "unprognostic (1.13e-3)" "unprognostic (2.23e-1)" "unprognostic (5.11e-2)" "unprognostic (1.06e-1)" "unprognostic (2.20e-1)" "unprognostic (1.25e-1)" "unprognostic (2.66e-2)" "unprognostic (5.21e-2)" "potential prognostic unfavorable (4.90e-4)" "unprognostic (1.14e-2)" "potential prognostic favorable (1.52e-5)" "unprognostic (2.98e-2)" "unprognostic (5.05e-3)" "unprognostic (3.46e-1)" "unprognostic (3.14e-2)" "unprognostic (1.71e-2)" "unprognostic (9.09e-2)" "unprognostic (5.90e-2)" "unprognostic (1.63e-1)" "unprognostic (1.11e-1)" "unprognostic (1.28e-1)" "unprognostic (2.00e-2)" "unprognostic (3.58e-1)" "unprognostic (2.94e-1)" "unprognostic (1.43e-1)" "unprognostic (1.34e-1)" "unprognostic (1.50e-1)" "unprognostic (9.41e-2)" "unprognostic (1.72e-1)" "unprognostic (1.20e-1)" "unprognostic (5.91e-2)" ADAP2 CENTA2 ENSG00000184060 "ArfGAP with dual PH domains 2" Q9NPF8 17 30906344-30959322 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 144.2;Hofbauer cells: 333.9;Kupffer cells: 470.4;Macrophages: 244.7;Microglia: 227.0;monocytes: 108.4" "Group enriched" "Detected in all" 5 "central nervous system macrophage: 292.4;pericyte: 150.9;vascular associated smooth muscle cell: 77.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "classical monocyte: 22.5;intermediate monocyte: 34.4;myeloid DC: 12.6;non-classical monocyte: 43.7" "Group enriched" "Detected in many" 9 "dendritic cells: 12.6;monocytes: 43.7" "Cancer enhanced" "Detected in many" "Kidney cancer: 7.7" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Minor Salivary Gland - Macrophages, Prostate - Macrophages, Spleen - Macrophages, Stomach - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 3: Rhabdoid - Membrane components" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 2 "unprognostic (1.55e-1)" "unprognostic (1.81e-2)" "unprognostic (9.02e-2)" "unprognostic (1.43e-2)" "unprognostic (4.89e-2)" "unprognostic (5.91e-2)" "unprognostic (5.97e-2)" "unprognostic (1.12e-1)" "potential prognostic favorable (3.58e-4)" "unprognostic (1.45e-1)" "unprognostic (3.90e-1)" "unprognostic (1.56e-1)" "unprognostic (7.32e-2)" "potential prognostic unfavorable (7.74e-4)" "unprognostic (2.57e-2)" "unprognostic (6.52e-2)" "unprognostic (1.17e-3)" "unprognostic (1.78e-2)" "unprognostic (7.04e-2)" "unprognostic (9.31e-2)" "unprognostic (1.03e-1)" "unprognostic (3.71e-1)" "unprognostic (5.89e-3)" "unprognostic (2.65e-2)" "unprognostic (1.26e-1)" "unprognostic (1.63e-2)" "unprognostic (1.89e-1)" "unprognostic (5.05e-2)" "unprognostic (1.86e-2)" "unprognostic (5.96e-2)" "unprognostic (1.36e-1)" ADAR "ADAR1, DRADA, G1P1, IFI4" ENSG00000160710 "Adenosine deaminase RNA specific" P55265 1 154581695-154628013 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity, mRNA processing, RNA-mediated gene silencing" "DNA-binding, Hydrolase, RNA-binding" "Aicardi-Goutieres syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 335.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003890, HPA051519, CAB056157" Enhanced Enhanced Nucleoplasm,Nucleoli No No 2400000 "Cluster 7: Non-specific - Innate immune response" "Cluster 61: Non-specific - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 68 Nucleoli Nucleoplasm "CAB056157: , HPA003890: , HPA051519: " "unprognostic (3.47e-2)" "unprognostic (4.39e-2)" "unprognostic (2.98e-3)" "unprognostic (6.46e-3)" "unprognostic (7.32e-2)" "unprognostic (2.19e-1)" "unprognostic (1.52e-1)" "unprognostic (8.87e-2)" "unprognostic (8.67e-2)" "unprognostic (3.36e-2)" "potential prognostic favorable (5.50e-7)" "unprognostic (4.62e-2)" "unprognostic (3.11e-2)" "unprognostic (7.54e-2)" "unprognostic (1.09e-1)" "unprognostic (1.22e-2)" "potential prognostic unfavorable (8.44e-4)" "unprognostic (1.30e-1)" "unprognostic (1.28e-1)" "unprognostic (2.02e-1)" "unprognostic (8.28e-2)" "unprognostic (1.04e-2)" "unprognostic (2.52e-1)" "unprognostic (7.20e-2)" "unprognostic (1.55e-1)" "unprognostic (1.99e-1)" "unprognostic (4.23e-1)" "unprognostic (2.36e-1)" "unprognostic (2.74e-1)" "unprognostic (3.76e-2)" "unprognostic (2.19e-1)" ADARB1 "ADAR2, ADAR2a, ADAR2a-L1, ADAR2a-L2, ADAR2a-L3, ADAR2b, ADAR2c, ADAR2d, ADAR2g, DRABA2, DRADA2, hRED1, RED1" ENSG00000197381 "Adenosine deaminase RNA specific B1" P78563 21 45073853-45226560 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity, mRNA processing" "Hydrolase, RNA-binding" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 110.4" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 172.7;Epicardial cells: 211.5;Myosatellite cells: 214.9;Retinal amacrine cells: 266.4;Retinal bipolar cells: 183.3;Smooth muscle cells: 185.4;Thymic myoid cells: 354.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Fibroblasts, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029645 Supported Nucleoplasm,Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 74: Non-specific - Signal transduction" "Cluster 24: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 62: Smooth muscle cells - Muscle contraction" 47 Nucleoplasm Cytosol "HPA029645: " "unprognostic (7.52e-3)" "unprognostic (3.19e-1)" "unprognostic (4.67e-2)" "unprognostic (1.07e-2)" "unprognostic (1.56e-1)" "unprognostic (3.26e-1)" "unprognostic (1.33e-2)" "unprognostic (1.28e-1)" "unprognostic (1.08e-1)" "unprognostic (2.05e-1)" "validated prognostic favorable (3.41e-4)" "validated prognostic favorable (3.60e-4)" "unprognostic (3.17e-1)" "unprognostic (1.90e-1)" "potential prognostic favorable (3.47e-5)" "unprognostic (1.45e-1)" "unprognostic (1.26e-1)" "unprognostic (6.42e-2)" "unprognostic (2.13e-1)" "unprognostic (3.70e-2)" "unprognostic (9.55e-3)" "unprognostic (8.65e-2)" "unprognostic (2.80e-1)" "unprognostic (6.45e-2)" "unprognostic (3.69e-3)" "unprognostic (2.04e-2)" "unprognostic (2.46e-1)" "unprognostic (3.98e-3)" "unprognostic (1.70e-1)" "unprognostic (1.24e-2)" "unprognostic (9.81e-3)" ADARB2 "ADAR3, hRED2, RED2" ENSG00000185736 "Adenosine deaminase RNA specific B2 (inactive)" Q9NS39 10 1177313-1737525 "Predicted intracellular proteins" "mRNA processing" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "brain: 32.5" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 1234.7;Oligodendrocyte progenitor cells: 1295.5;Other brain neurons: 392.8;Respiratory basal cells: 621.0;Respiratory ionocytes: 370.8;Retinal amacrine cells: 919.5;Retinal bipolar cells: 644.1;Salivary basal cells: 583.2;Salivary ionocytes: 915.9;Thyrotrophs: 986.3" "Cell type enhanced" "Detected in all" "CGE interneuron: 6682.1;mammillary body: 4248.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "neutrophil: 4.7" "Lineage enriched" "Detected in many" 4 "granulocytes: 4.7" "Cancer enhanced" "Detected in some" "cervical cancer: 2.6" "Pituitary gland - Thyrotropes, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031333 Approved Nucleoplasm,Mitochondria,Cytosol NA NA 73000000 "Cluster 3: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" Nucleoplasm "Mitochondria, Cytosol" "HPA031333: " "unprognostic (4.41e-2)" "unprognostic (3.62e-1)" "unprognostic (9.79e-2)" "unprognostic (2.82e-1)" ADAT1 ENSG00000065457 "Adenosine deaminase tRNA specific 1" Q9BUB4 16 75596868-75623300 "Enzymes, Predicted intracellular proteins" "tRNA processing" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 54.8;Late spermatids: 160.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040713, HPA040903" Approved Supported Nucleoplasm NA NA "Cluster 32: Basophils - Transcription" "Cluster 67: Testis - Mixed function" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 9: T-cells - Adaptive immunity: Regulation" Nucleoplasm "HPA040713: , HPA040903: " "unprognostic (4.19e-2)" "unprognostic (1.39e-2)" "unprognostic (1.63e-2)" "unprognostic (7.83e-2)" "unprognostic (9.80e-3)" "unprognostic (2.67e-1)" "unprognostic (2.21e-1)" "unprognostic (9.19e-2)" "potential prognostic unfavorable (2.73e-5)" "unprognostic (9.76e-2)" "unprognostic (7.89e-3)" "unprognostic (1.93e-2)" "unprognostic (1.02e-3)" "unprognostic (3.75e-2)" "unprognostic (1.25e-1)" "unprognostic (8.99e-2)" "unprognostic (2.03e-1)" "unprognostic (4.27e-2)" "unprognostic (3.94e-1)" "unprognostic (7.36e-3)" "unprognostic (7.87e-2)" "unprognostic (2.44e-1)" "unprognostic (1.02e-2)" "unprognostic (1.31e-1)" "unprognostic (3.18e-2)" "unprognostic (9.39e-2)" "unprognostic (2.64e-2)" "unprognostic (2.49e-2)" "unprognostic (2.67e-1)" "unprognostic (2.64e-1)" "unprognostic (3.27e-1)" ADAT2 "DEADC1, dJ20N2.1, TAD2" ENSG00000189007 "Adenosine deaminase tRNA specific 2" Q7Z6V5 6 143422832-143450695 "Enzymes, Predicted intracellular proteins" "tRNA processing" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Megakaryocyte-Erythroid progenitors: 58.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035479 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 49: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 56: Non-specific - Sensory perception" "Cluster 17: Non-specific - RNA processing" 4 "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA035479: " "unprognostic (2.03e-3)" "unprognostic (5.59e-2)" "unprognostic (1.30e-1)" "unprognostic (2.75e-2)" "unprognostic (1.03e-1)" "unprognostic (1.08e-2)" "unprognostic (7.32e-3)" "unprognostic (5.24e-2)" "unprognostic (6.81e-2)" "unprognostic (2.55e-3)" "unprognostic (1.82e-1)" "unprognostic (2.13e-1)" "unprognostic (1.59e-1)" "unprognostic (3.84e-2)" "unprognostic (8.12e-2)" "unprognostic (2.37e-2)" "unprognostic (2.75e-2)" "unprognostic (1.44e-1)" "unprognostic (7.06e-2)" "unprognostic (1.58e-1)" "unprognostic (1.49e-3)" "unprognostic (5.17e-2)" "unprognostic (2.96e-3)" "unprognostic (1.83e-2)" "unprognostic (1.62e-1)" "unprognostic (4.78e-3)" "unprognostic (3.10e-1)" "unprognostic (6.59e-2)" "unprognostic (2.38e-1)" ADAT3 TAD3 ENSG00000213638 "Adenosine deaminase tRNA specific 3" 19 1905399-1913447 "Human disease related genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 13.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA058899 Uncertain Approved Nucleoplasm No No "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 23: Non-specific - Transcription" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" Nucleoplasm "HPA058899: " "unprognostic (2.70e-1)" "unprognostic (2.48e-1)" "unprognostic (4.55e-2)" "unprognostic (1.94e-1)" "unprognostic (1.32e-1)" "unprognostic (1.04e-2)" "unprognostic (2.39e-1)" "potential prognostic favorable (7.44e-4)" "unprognostic (9.04e-2)" "unprognostic (1.30e-1)" "unprognostic (5.63e-1)" "unprognostic (2.69e-2)" "potential prognostic unfavorable (1.43e-5)" "unprognostic (2.87e-2)" "unprognostic (1.95e-1)" "unprognostic (5.39e-2)" "unprognostic (2.43e-1)" "unprognostic (3.69e-3)" "unprognostic (3.56e-2)" "unprognostic (1.10e-1)" "unprognostic (4.60e-2)" "unprognostic (1.06e-2)" "unprognostic (1.21e-2)" "unprognostic (2.56e-1)" "potential prognostic favorable (2.20e-4)" "unprognostic (1.41e-1)" "unprognostic (2.44e-2)" "unprognostic (4.76e-2)" ADCK1 FLJ39600 ENSG00000063761 "AarF domain containing kinase 1" Q86TW2 14 77800109-77935014 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 53.5;Cone photoreceptor cells: 62.1;Erythrocyte progenitors: 50.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051012, HPA055014" Uncertain Uncertain Nucleoplasm NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 7: Non-specific - Transcription" Nucleoplasm "HPA051012: , HPA055014: " "unprognostic (8.78e-3)" "unprognostic (1.61e-1)" "unprognostic (2.94e-1)" "unprognostic (1.14e-1)" "unprognostic (2.89e-1)" "unprognostic (2.16e-1)" "unprognostic (3.38e-1)" "unprognostic (4.76e-3)" "unprognostic (1.01e-1)" "unprognostic (1.03e-1)" "unprognostic (3.40e-2)" "unprognostic (9.28e-2)" "unprognostic (1.08e-2)" "potential prognostic unfavorable (8.92e-6)" "unprognostic (8.43e-2)" "unprognostic (3.34e-2)" "unprognostic (2.75e-1)" "unprognostic (1.81e-2)" "unprognostic (5.52e-2)" "unprognostic (8.77e-2)" "unprognostic (2.31e-1)" "unprognostic (4.15e-2)" "unprognostic (1.65e-1)" "unprognostic (1.01e-2)" "unprognostic (1.64e-1)" "unprognostic (2.69e-1)" "unprognostic (2.20e-1)" "unprognostic (2.75e-1)" "unprognostic (1.31e-1)" "unprognostic (1.29e-1)" "unprognostic (8.40e-2)" ADCK2 MGC20727 ENSG00000133597 "AarF domain containing kinase 2" Q7Z695 7 140672945-140696261 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 16.0;Microglia: 10.6" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 12.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036036 Approved Uncertain Centrosome,Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 1 "Centrosome, Cytosol" "HPA036036: " "unprognostic (5.99e-2)" "unprognostic (2.62e-1)" "unprognostic (6.24e-2)" "unprognostic (3.09e-2)" "unprognostic (1.85e-2)" "unprognostic (2.37e-1)" "unprognostic (4.04e-3)" "unprognostic (3.57e-2)" "unprognostic (9.54e-2)" "unprognostic (3.48e-2)" "unprognostic (1.57e-3)" "unprognostic (2.13e-1)" "unprognostic (5.18e-2)" "unprognostic (1.32e-2)" "potential prognostic unfavorable (4.66e-5)" "unprognostic (9.21e-2)" "unprognostic (2.75e-2)" "unprognostic (2.79e-2)" "unprognostic (1.79e-1)" "unprognostic (6.75e-3)" "unprognostic (1.46e-1)" "unprognostic (1.40e-2)" "unprognostic (6.92e-2)" "unprognostic (7.38e-2)" "unprognostic (1.34e-1)" "unprognostic (1.34e-1)" "unprognostic (2.88e-2)" "unprognostic (2.20e-2)" "unprognostic (1.67e-1)" "unprognostic (8.09e-2)" "unprognostic (2.14e-1)" ADCK5 FLJ35454 ENSG00000173137 "AarF domain containing kinase 5" Q3MIX3 8 144373101-144393242 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 27.3;Enterocytes: 36.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025692, HPA028679" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 64: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 1: Enterocytes - Absorption and Digestion" 3 "Plasma membrane, Cytosol" "HPA025692: , HPA028679: " "unprognostic (5.70e-2)" "unprognostic (1.25e-2)" "unprognostic (3.62e-1)" "unprognostic (8.54e-3)" "unprognostic (5.58e-2)" "unprognostic (7.61e-2)" "unprognostic (4.16e-2)" "unprognostic (2.23e-2)" "unprognostic (3.48e-1)" "unprognostic (1.08e-1)" "unprognostic (4.46e-3)" "unprognostic (2.28e-1)" "unprognostic (1.28e-2)" "unprognostic (8.57e-2)" "unprognostic (2.58e-1)" "unprognostic (2.88e-1)" "unprognostic (2.82e-1)" "unprognostic (1.23e-1)" "unprognostic (1.40e-3)" "unprognostic (4.35e-1)" "unprognostic (1.09e-2)" "unprognostic (8.81e-2)" "unprognostic (1.47e-1)" "unprognostic (1.99e-1)" "unprognostic (1.55e-1)" "unprognostic (5.99e-2)" "unprognostic (2.34e-1)" "unprognostic (4.01e-1)" "unprognostic (1.25e-1)" ADCY1 "AC1, DFNB44" ENSG00000164742 "Adenylate cyclase 1" Q08828 7 45574140-45723116 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms, cAMP biosynthesis" "Calmodulin-binding, Lyase" "Cancer-related genes, Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 33.9;liver: 17.8;retina: 49.2" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 170.1;Brain inhibitory neurons: 116.2;Cone photoreceptor cells: 598.3;Decidual stromal cells: 122.4;Endometrial stromal cells: 87.8;Hepatocytes: 103.1;Oligodendrocyte progenitor cells: 126.0;Retinal amacrine cells: 172.9;Rod photoreceptor cells: 387.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 17.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 26.1" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018364, HPA068274" Uncertain Uncertain Mitochondria NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 79: Photoreceptor cells - Phototransduction" 1 Mitochondria "CAB018364: , HPA068274: " "unprognostic (1.14e-1)" "unprognostic (4.65e-2)" "unprognostic (9.64e-2)" "unprognostic (7.99e-2)" "unprognostic (2.20e-1)" "unprognostic (1.12e-2)" "unprognostic (1.42e-1)" "unprognostic (2.92e-2)" "validated prognostic favorable (3.29e-5)" "validated prognostic favorable (4.71e-4)" "unprognostic (1.11e-1)" "unprognostic (2.59e-2)" "unprognostic (2.71e-2)" "unprognostic (7.17e-3)" "unprognostic (1.01e-1)" "unprognostic (4.40e-2)" "unprognostic (2.55e-2)" "unprognostic (5.52e-2)" "unprognostic (1.07e-1)" "unprognostic (5.44e-3)" "unprognostic (1.84e-2)" "unprognostic (4.56e-1)" "unprognostic (9.07e-3)" "unprognostic (2.88e-1)" "unprognostic (4.34e-2)" ADCY10 "HCA2, RP1-313L4.2, SAC, SACI, Sacy" ENSG00000143199 "Adenylate cyclase 10" Q96PN6 1 167809386-167914215 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "liver: 5.7;testis: 16.4" "Group enriched" "Detected in many" 6 "Early spermatids: 111.8;Late primary spermatocytes: 88.3;Late spermatids: 133.4" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in single" 6 "Liver Hepatocellular Carcinoma (TCGA): 3.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA015243, HPA017749" Approved NA NA "Cluster 47: Testis - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 1 "HPA015243: , HPA017749: " "unprognostic (3.90e-2)" "unprognostic (2.23e-2)" "unprognostic (2.71e-3)" ADCY2 "AC2, HBAC2, KIAA1060" ENSG00000078295 "Adenylate cyclase 2" Q08462 5 7396138-7830081 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 35.4;skeletal muscle: 64.1;tongue: 28.8" "Cell type enhanced" "Detected in many" "Astrocytes: 1338.0;Bergmann glia: 1176.4;Corticotrophs: 785.5;Ependymal cells: 987.9;Gonadotrophs: 569.0;Myonuclei: 1905.9;Retinal horizontal cells: 1071.8;Thymic myoid cells: 1429.0;Thyrotrophs: 554.7" "Cell type enhanced" "Detected in all" "astrocyte: 1868.4" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 18.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 5.0;testis cancer: 3.5" "Breast - Fibroblasts, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB031482, HPA038015, HPA038483" Approved Approved "Nuclear membrane,Golgi apparatus,Vesicles,Primary cilium" NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 51: Neurons - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" "Golgi apparatus, Vesicles" "Nuclear membrane, Primary cilium" "CAB031482: , HPA038015: , HPA038483: " "unprognostic (1.24e-1)" "unprognostic (1.27e-2)" "unprognostic (3.81e-1)" "unprognostic (3.05e-2)" "potential prognostic favorable (5.43e-5)" "unprognostic (1.45e-2)" "potential prognostic favorable (9.05e-6)" "unprognostic (3.10e-2)" "unprognostic (5.00e-3)" "unprognostic (1.78e-2)" "unprognostic (1.12e-1)" "unprognostic (1.95e-1)" "unprognostic (2.55e-3)" "unprognostic (4.35e-1)" "unprognostic (2.21e-1)" ADCY3 AC3 ENSG00000138031 "Adenylate cyclase 3" O60266 2 24819169-24920237 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis, Olfaction, Sensory transduction" "Calmodulin-binding, Lyase" Obesity "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 277.4;Decidual stromal cells: 122.6;Endometrial stromal cells: 107.0;Leydig cells: 110.9;Pericytes: 335.0;Retinal ganglion cells: 158.4;Somatotrophs: 144.7;Vascular smooth muscle cells: 248.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Skin - Macrophages, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010223, HPA068616" Approved Uncertain "Nucleoplasm,Nucleoli,Golgi apparatus,Plasma membrane,Primary cilium,Primary cilium transition zone,Basal body" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 75: Ovary - Mixed function" "Cluster 33: Neurons - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 110: Mural cells - ECM organization" 14 "Nucleoplasm, Primary cilium" "Nucleoli, Golgi apparatus, Plasma membrane, Primary cilium transition zone, Basal body" "CAB010223: , HPA068616: " "unprognostic (8.72e-3)" "unprognostic (1.13e-1)" "unprognostic (1.99e-1)" "unprognostic (4.97e-2)" "unprognostic (1.49e-1)" "unprognostic (2.50e-2)" "unprognostic (7.79e-3)" "unprognostic (1.17e-1)" "unprognostic (1.20e-1)" "unprognostic (3.37e-2)" "unprognostic (3.38e-2)" "unprognostic (4.86e-2)" "unprognostic (1.91e-3)" "unprognostic (1.50e-1)" "unprognostic (2.53e-1)" "unprognostic (7.56e-2)" "unprognostic (2.49e-2)" "unprognostic (2.64e-3)" "unprognostic (3.36e-2)" "unprognostic (1.78e-1)" "unprognostic (6.48e-3)" "unprognostic (1.42e-2)" "unprognostic (4.03e-1)" "unprognostic (2.09e-1)" "unprognostic (3.85e-2)" "potential prognostic favorable (6.24e-4)" "unprognostic (4.23e-1)" "unprognostic (1.63e-1)" "unprognostic (1.23e-1)" "unprognostic (3.45e-2)" "unprognostic (1.13e-2)" ADCY4 AC4 ENSG00000129467 "Adenylate cyclase 4" Q8NFM4 14 24318349-24335093 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Epicardial cells: 9.1;Foveolar cells: 5.3;Late spermatids: 8.0;Lymphatic endothelial cells: 26.7;Pericytes: 4.2;Vascular endothelial cells: 39.2" "Cell type enriched" "Detected in some" 8 "endothelial cell: 108.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "basophil: 2.9" "Lineage enriched" "Detected in single" 9 "granulocytes: 2.9" "Not detected" "Not detected" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Pancreas - Endothelial cells, Pituitary gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells, Thyroid gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005070, HPA048344" Approved Approved "Nucleoplasm,Plasma membrane,Mitochondria" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 104: Brain endothelial cells - Blood brain barrier" 3 Mitochondria "Nucleoplasm, Plasma membrane" "CAB005070: , HPA048344: " "unprognostic (2.90e-1)" "unprognostic (4.31e-3)" "unprognostic (2.32e-1)" "unprognostic (1.74e-1)" "unprognostic (1.37e-2)" "potential prognostic favorable (1.99e-7)" "unprognostic (1.18e-3)" "potential prognostic favorable (1.64e-4)" "unprognostic (1.68e-1)" "unprognostic (9.01e-2)" "unprognostic (2.98e-2)" "unprognostic (1.12e-1)" "unprognostic (9.06e-2)" "unprognostic (2.38e-2)" "unprognostic (5.71e-2)" "unprognostic (5.23e-2)" ADCY5 AC5 ENSG00000173175 "Adenylate cyclase 5" O95622 3 123282296-123449090 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 74.2;heart muscle: 99.3" "Cell type enhanced" "Detected in many" "Adipocytes: 247.0;Brain inhibitory neurons: 248.8;Cardiomyocytes: 313.3;Gonadotrophs: 174.6;Lactotrophs: 137.2;Loop of henle epithelial cells: 140.6;Oligodendrocytes: 127.2;Peritubular myoid cells: 288.5;Somatotrophs: 135.3;Thyrotrophs: 222.5;Vascular smooth muscle cells: 180.3" "Cell type enhanced" "Detected in all" "eccentric medium spiny neuron: 336.9;medium spiny neuron: 668.8" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 19.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 8.4" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Liver - Hepatic stellate cells, Lung - Smooth muscle cells, Minor Salivary Gland - Smooth muscle cells, Thyroid gland - Smooth muscle cells" "Region enriched" "Detected in all" 5 "basal ganglia: 388.1" "Region enriched" "Detected in all" 6 "basal ganglia: 206.2" "HPA017730, HPA077682" Uncertain Approved "Nucleoplasm,Nuclear bodies,Vesicles,Plasma membrane,Primary cilium" NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 33: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" 1 "Vesicles, Plasma membrane" "Nucleoplasm, Nuclear bodies, Primary cilium" "HPA017730: , HPA077682: " "unprognostic (1.08e-2)" "unprognostic (6.13e-2)" "unprognostic (1.66e-2)" "potential prognostic favorable (3.19e-4)" "unprognostic (5.94e-2)" "unprognostic (2.67e-1)" "unprognostic (1.40e-1)" "potential prognostic favorable (1.87e-4)" "unprognostic (1.09e-2)" "unprognostic (2.83e-1)" "potential prognostic favorable (4.14e-10)" "unprognostic (3.47e-3)" "unprognostic (1.76e-2)" "unprognostic (3.00e-1)" "unprognostic (9.27e-3)" "unprognostic (1.01e-2)" "unprognostic (5.22e-2)" "unprognostic (3.31e-2)" "unprognostic (1.26e-2)" "unprognostic (1.35e-1)" "unprognostic (4.58e-1)" "unprognostic (2.31e-2)" "unprognostic (1.54e-1)" "unprognostic (3.99e-2)" "unprognostic (5.62e-2)" "unprognostic (1.15e-1)" "unprognostic (1.28e-2)" "unprognostic (8.51e-2)" "unprognostic (2.33e-1)" ADCY6 AC6 ENSG00000174233 "Adenylate cyclase 6" O43306 12 48766194-48789089 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 134.9;Adrenal medulla cells: 74.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB018365 Approved Approved "Golgi apparatus" NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 89: Adipocytes - Lipid metabolism" 2 "Golgi apparatus" "CAB018365: " "unprognostic (5.07e-2)" "unprognostic (1.12e-2)" "unprognostic (3.31e-1)" "potential prognostic unfavorable (8.38e-4)" "unprognostic (4.72e-2)" "unprognostic (6.99e-2)" "unprognostic (3.66e-1)" "unprognostic (2.29e-1)" "unprognostic (4.43e-2)" "unprognostic (1.40e-1)" "validated prognostic favorable (9.71e-6)" "validated prognostic favorable (2.64e-4)" "unprognostic (3.65e-2)" "unprognostic (5.52e-2)" "unprognostic (2.14e-2)" "unprognostic (6.58e-2)" "unprognostic (9.57e-2)" "unprognostic (3.30e-2)" "unprognostic (9.66e-2)" "unprognostic (1.43e-1)" "unprognostic (1.02e-1)" "unprognostic (3.12e-1)" "unprognostic (1.22e-1)" "unprognostic (2.12e-2)" "unprognostic (3.24e-2)" "unprognostic (4.73e-2)" "unprognostic (1.34e-1)" "unprognostic (4.15e-3)" "unprognostic (2.43e-1)" "unprognostic (4.56e-2)" "unprognostic (2.57e-2)" ADCY7 "AC7, KIAA0037" ENSG00000121281 "Adenylate cyclase 7" P51828 16 50246137-50318135 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 27.9" "Cell type enhanced" "Detected in many" "cDC: 128.9;Erythrocyte progenitors: 63.8;Hofbauer cells: 78.7;Kupffer cells: 83.0;Macrophages: 97.2;Microglia: 185.4;Monocyte progenitors: 87.8;monocytes: 93.5;Myosatellite cells: 61.6;Neutrophils: 64.6;NK-cells: 101.2" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 237.1;leukocyte: 143.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adrenal gland - Macrophages, Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA041218, HPA048241" Uncertain Approved "Vesicles,Plasma membrane,Rods & Rings" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 1 "Plasma membrane" "Vesicles, Rods & Rings" "HPA041218: , HPA048241: " "unprognostic (1.26e-2)" "unprognostic (2.33e-1)" "unprognostic (5.21e-2)" "potential prognostic unfavorable (2.01e-4)" "unprognostic (1.35e-1)" "unprognostic (1.94e-1)" "unprognostic (3.20e-1)" "unprognostic (1.69e-2)" "unprognostic (2.02e-1)" "unprognostic (5.11e-2)" "unprognostic (3.87e-1)" "unprognostic (1.03e-1)" "unprognostic (3.13e-2)" "unprognostic (8.27e-3)" "unprognostic (2.63e-2)" "unprognostic (8.46e-2)" "unprognostic (3.32e-1)" "unprognostic (1.55e-3)" "unprognostic (1.41e-2)" "unprognostic (3.38e-2)" "unprognostic (4.39e-2)" "unprognostic (1.95e-1)" "unprognostic (2.36e-3)" "unprognostic (1.07e-1)" "unprognostic (3.73e-2)" "unprognostic (1.54e-3)" "unprognostic (1.67e-1)" "unprognostic (2.36e-1)" "unprognostic (1.68e-2)" "unprognostic (1.03e-1)" "unprognostic (4.40e-2)" ADCY8 "AC8, ADCY3, HBAC1" ENSG00000155897 "Adenylate cyclase 8" P40145 8 130780301-131040909 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 8.0;epididymis: 21.5" "Cell type enhanced" "Detected in some" "Astrocytes: 365.7;Brain excitatory neurons: 98.5;Brain inhibitory neurons: 131.2;Ependymal cells: 75.4;Epididymal efferent duct absorptive cells: 285.4;Epididymal principal cells: 100.9;Fallopian secretory cells: 62.2;Oligodendrocyte progenitor cells: 209.9;Retinal amacrine cells: 449.8;Retinal ganglion cells: 224.0" "Cell type enhanced" "Detected in all" "astrocyte: 652.9" "Cancer enriched" "Detected in some" 4 "Glioblastoma Multiforme (TCGA): 14.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 2.2;Rhabdoid: 1.1" "Lung - Alveolar cells type 2, Skin - Eccrine sweat gland cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018652, HPA024291" Supported Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 109: Neurons - Neuronal signaling" 1 "Plasma membrane, Cytosol" Nucleoplasm "CAB018652: , HPA024291: " "unprognostic (1.28e-1)" "unprognostic (1.91e-1)" "potential prognostic favorable (7.23e-4)" "unprognostic (3.06e-2)" "unprognostic (1.76e-1)" "unprognostic (1.23e-1)" "unprognostic (8.51e-2)" "unprognostic (2.01e-1)" "unprognostic (3.52e-2)" "unprognostic (9.63e-2)" ADCY9 AC9 ENSG00000162104 "Adenylate cyclase 9" O60503 16 3953387-4116442 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 48.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 294.6;Choroid plexus epithelial cells: 791.3;Myonuclei: 588.6;Oocytes: 350.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041328, HPA044225" Approved Approved "Plasma membrane,Primary cilium,Basal body,Cytosol" NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 23: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 7 "Plasma membrane, Cytosol" "Primary cilium, Basal body" "HPA041328: , HPA044225: " "unprognostic (4.22e-2)" "unprognostic (1.72e-1)" "unprognostic (1.60e-1)" "unprognostic (1.30e-1)" "unprognostic (3.18e-1)" "unprognostic (1.68e-3)" "unprognostic (7.40e-2)" "unprognostic (2.14e-2)" "unprognostic (2.28e-2)" "unprognostic (2.35e-2)" "potential prognostic favorable (3.63e-11)" "unprognostic (1.36e-2)" "unprognostic (1.01e-2)" "unprognostic (3.92e-1)" "unprognostic (2.47e-1)" "unprognostic (2.43e-3)" "unprognostic (7.95e-3)" "unprognostic (9.43e-2)" "unprognostic (1.28e-1)" "unprognostic (6.35e-3)" "unprognostic (1.39e-1)" "unprognostic (1.70e-1)" "unprognostic (1.78e-1)" "unprognostic (4.51e-1)" "unprognostic (1.03e-1)" "unprognostic (1.11e-1)" "unprognostic (2.61e-1)" "unprognostic (9.43e-2)" "unprognostic (2.74e-1)" "unprognostic (3.81e-1)" "unprognostic (5.00e-3)" ADCYAP1 PACAP ENSG00000141433 "Adenylate cyclase activating polypeptide 1" P18509 18 904871-912172 "Predicted secreted proteins" Neurogenesis Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.5;lymphoid tissue: 10.3" "Cell type enriched" "Detected in some" 6 "Mast cells: 647.2" "Cell type enhanced" "Detected in many" "lower rhombic lip: 81.8;mammillary body: 125.3;thalamic excitatory: 71.2" "Group enriched" "Detected in some" 9 "Kidney Chromophobe (TCGA): 15.4;Pancreatic Adenocarcinoma (TCGA): 5.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 17.8;Rhabdoid: 20.7;thyroid cancer: 10.7" "Colon - Colon enteroendocrine cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA065887 Supported Supported "Secreted in other tissues" Hormone NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 43: Hindbrain - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 58: Mast cells - Allergic inflammatory responses" 2 "HPA065887: " "unprognostic (2.54e-1)" "unprognostic (2.36e-1)" "unprognostic (3.26e-2)" "unprognostic (1.86e-1)" "unprognostic (1.86e-2)" "unprognostic (5.96e-3)" "unprognostic (3.68e-2)" "unprognostic (2.84e-1)" "unprognostic (2.44e-3)" "unprognostic (3.43e-2)" "unprognostic (8.03e-2)" "unprognostic (1.47e-2)" ADCYAP1R1 "PAC1, PAC1R, PACAPR" ENSG00000078549 "ADCYAP receptor type I" P41586 7 31052308-31111474 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Spermatogenesis" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 76.2;fallopian tube: 28.5" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 127.6;Astrocytes: 95.3;Bergmann glia: 20.4;Brain excitatory neurons: 25.1;Brain inhibitory neurons: 36.0;Ependymal cells: 21.7;Oligodendrocyte progenitor cells: 21.5;Other brain neurons: 44.1;Pericytes: 21.0;Pituicytes/FSCs: 151.5;Pituitary stem cells: 53.3" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in some" 13 "Glioblastoma Multiforme (TCGA): 74.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 16 "Neuroblastoma: 36.1" "Adrenal gland - Adrenal medulla cells, Pancreas - Fibroblasts, Pituitary gland - Undifferentiated cells (Pituitary gland), Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030739, HPA049877" Enhanced Enhanced Vesicles NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 1 Vesicles "HPA030739: , HPA049877: " "unprognostic (1.27e-3)" "unprognostic (4.94e-2)" "unprognostic (9.11e-2)" "unprognostic (3.73e-1)" "unprognostic (1.77e-1)" "unprognostic (3.11e-1)" "unprognostic (3.36e-2)" "unprognostic (3.84e-2)" ADD1 ENSG00000087274 "Adducin 1" P35611 4 2843844-2930076 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 498.9;Rod photoreceptor cells: 990.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Kidney - Fibroblasts, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009794, HPA035873, HPA035874" Enhanced Enhanced "Nucleoplasm,Plasma membrane" NA NA 720000 "Cluster 14: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 79: Photoreceptor cells - Phototransduction" 17 "Plasma membrane" Nucleoplasm "CAB009794: , HPA035873: , HPA035874: " "unprognostic (7.79e-3)" "unprognostic (6.30e-2)" "unprognostic (7.88e-2)" "unprognostic (2.84e-3)" "unprognostic (1.40e-1)" "unprognostic (2.27e-1)" "unprognostic (7.26e-2)" "unprognostic (1.14e-3)" "unprognostic (7.65e-2)" "unprognostic (6.98e-2)" "validated prognostic favorable (4.82e-8)" "validated prognostic favorable (4.23e-6)" "unprognostic (6.24e-3)" "unprognostic (3.21e-3)" "unprognostic (8.48e-3)" "unprognostic (1.96e-1)" "unprognostic (9.69e-3)" "unprognostic (4.36e-3)" "unprognostic (3.47e-2)" "unprognostic (1.30e-1)" "unprognostic (6.23e-2)" "unprognostic (1.48e-1)" "unprognostic (8.19e-2)" "unprognostic (1.19e-1)" "unprognostic (7.96e-2)" "unprognostic (8.29e-2)" "unprognostic (2.63e-1)" "unprognostic (4.41e-2)" "unprognostic (1.49e-1)" "unprognostic (1.58e-1)" "unprognostic (9.48e-2)" ADD2 ADDB ENSG00000075340 "Adducin 2" P35612 2 70607618-70768225 "Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 62.7;brain: 36.1" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 162.0;Brain inhibitory neurons: 124.1;Early spermatids: 79.9;Erythrocyte progenitors: 246.5;Lactotrophs: 77.6;Late spermatids: 91.3;Other brain neurons: 90.1;Retinal amacrine cells: 86.9;Retinal bipolar cells: 56.5;Retinal ganglion cells: 231.8;Retinal horizontal cells: 420.7" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Glioblastoma Multiforme (TCGA): 16.6;Testicular Germ Cell Tumor (TCGA): 40.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 2.3;non-classical monocyte: 2.3" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Neuroblastoma: 43.0" "Adrenal gland - Adrenal medulla cells, Breast - Endothelial cells, Minor Salivary Gland - Endothelial cells, Pituitary gland - Lactotropes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009796, HPA034509, HPA034510" Supported Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 47000 "Cluster 14: Non-specific - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 24: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 109: Neurons - Neuronal signaling" 8 "Nucleoplasm, Cytosol" "Plasma membrane" "CAB009796: , HPA034509: , HPA034510: " "unprognostic (1.35e-1)" "unprognostic (1.25e-1)" "unprognostic (2.21e-1)" "unprognostic (2.93e-3)" "unprognostic (2.13e-1)" "potential prognostic favorable (1.33e-4)" "unprognostic (3.54e-2)" "unprognostic (1.17e-1)" "unprognostic (2.06e-2)" "unprognostic (3.73e-2)" "unprognostic (1.02e-1)" "unprognostic (1.46e-2)" "unprognostic (4.25e-2)" "unprognostic (8.25e-2)" "unprognostic (1.43e-1)" "unprognostic (2.93e-2)" "unprognostic (3.29e-1)" "unprognostic (7.65e-2)" ADD3 ADDL ENSG00000148700 "Adducin 3" Q9UEY8 10 109996368-110135565 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 796.6;Neutrophils: 898.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Breast - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009797, HPA035696" Supported Supported "Plasma membrane" NA NA 120000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 36: Brain & Liver - Signaling" "Cluster 39: Astrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 9 "Plasma membrane" "CAB009797: , HPA035696: " "unprognostic (2.34e-2)" "unprognostic (1.01e-1)" "unprognostic (1.09e-1)" "unprognostic (1.46e-1)" "unprognostic (1.08e-1)" "unprognostic (1.07e-2)" "unprognostic (1.49e-1)" "unprognostic (8.10e-2)" "unprognostic (1.30e-2)" "unprognostic (3.74e-2)" "potential prognostic favorable (2.65e-9)" "unprognostic (1.27e-3)" "unprognostic (1.05e-1)" "unprognostic (3.18e-3)" "unprognostic (1.73e-1)" "unprognostic (3.00e-1)" "unprognostic (2.52e-2)" "unprognostic (1.76e-2)" "unprognostic (1.25e-1)" "unprognostic (9.51e-3)" "potential prognostic unfavorable (5.32e-4)" "unprognostic (1.02e-2)" "unprognostic (1.69e-1)" "unprognostic (3.09e-1)" "unprognostic (7.61e-3)" "unprognostic (4.68e-2)" "unprognostic (6.66e-2)" "unprognostic (2.74e-1)" "unprognostic (3.55e-1)" "unprognostic (5.54e-2)" "unprognostic (3.46e-1)" ADGB "C6orf103, CAPN16, dJ408K24.1, FLJ23121" ENSG00000118492 Androglobin Q8N7X0 6 146598967-146815462 "Enzymes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 4.7;fallopian tube: 7.1;testis: 24.4" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 300.3;Early spermatids: 365.9;Endometrial ciliated cells: 299.8;Ependymal cells: 1253.3;Epididymal efferent duct ciliated cells: 260.2;Fallopian tube ciliated cells: 344.0;Late primary spermatocytes: 356.5;Respiratory ciliated cells: 690.9" "Cell type enriched" "Detected in many" 5 "ependymal cell: 1392.5" "Cancer enhanced" "Detected in single" "Uterine Corpus Endometrial Carcinoma (TCGA): 1.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Skin - Langerhans cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA036340 Enhanced Approved "Mid piece" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 34: Ciliated cells - Cilia assembly & function" "Mid piece" "HPA036340: " "unprognostic (1.47e-1)" ADGRA1 "GPR123, KIAA1828" ENSG00000197177 "Adhesion G protein-coupled receptor A1" Q86SQ6 10 133087924-133131675 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 26.2" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 31.9;Brain excitatory neurons: 19.2;Brain inhibitory neurons: 17.0;Corticotrophs: 9.4;Ependymal cells: 28.2;Oligodendrocyte progenitor cells: 54.9;Other brain neurons: 19.6;Retinal amacrine cells: 38.8;Salivary duct cells: 27.1" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in some" 4 "Glioblastoma Multiforme (TCGA): 8.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Bone cancer: 6.5" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Liver - Sinusoid Endothelial cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary gland ductal cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042773 Approved NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" "HPA042773: " "unprognostic (2.16e-1)" "potential prognostic favorable (1.12e-4)" "unprognostic (9.86e-2)" ADGRA2 "DKFZp434C211, DKFZp434J0911, FLJ14390, GPR124, KIAA1531, TEM5" ENSG00000020181 "Adhesion G protein-coupled receptor A2" Q96PE1 8 37784191-37844896 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Wnt signaling pathway" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 36.5;Endometrial glandular cells: 35.5;Endometrial luminal cells: 83.1;Endometrial stromal cells: 63.5;Fibro-adipogenic progenitors: 44.2;Fibroblasts: 53.5;Hepatic stellate cells: 51.6;Leydig cells: 84.1;Lymphatic endothelial cells: 46.4;Müller glia: 73.4;Pericytes: 74.5;Peritubular myoid cells: 53.4;Smooth muscle cells: 46.1;Vascular smooth muscle cells: 69.7" "Cell type enhanced" "Detected in many" "fibroblast: 101.6;pericyte: 98.3;vascular associated smooth muscle cell: 139.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 29.9" "Adrenal gland - Fibroblasts, Breast - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Minor Salivary Gland - Fibroblasts, Pituitary gland - Fibroblasts, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008984, HPA012393" Uncertain Supported "Vesicles,Plasma membrane" NA NA 73000 "Cluster 75: Ovary - Mixed function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 110: Mural cells - ECM organization" 4 "Plasma membrane" Vesicles "HPA008984: , HPA012393: " "unprognostic (1.16e-3)" "unprognostic (6.20e-2)" "unprognostic (5.00e-3)" "unprognostic (2.18e-2)" "unprognostic (5.00e-2)" "unprognostic (1.60e-1)" "unprognostic (6.18e-2)" "unprognostic (9.96e-2)" "unprognostic (1.07e-2)" "unprognostic (3.64e-3)" "potential prognostic favorable (9.02e-4)" "potential prognostic unfavorable (2.00e-5)" "unprognostic (7.04e-2)" "unprognostic (7.48e-2)" "unprognostic (7.98e-3)" "unprognostic (3.06e-2)" "unprognostic (2.93e-1)" "unprognostic (1.21e-2)" "unprognostic (3.07e-2)" "unprognostic (1.64e-1)" "unprognostic (1.90e-2)" "unprognostic (3.39e-2)" "unprognostic (2.57e-1)" "unprognostic (1.58e-2)" "potential prognostic unfavorable (2.34e-4)" "unprognostic (2.09e-2)" "unprognostic (1.51e-1)" "unprognostic (7.14e-2)" "unprognostic (2.09e-1)" ADGRA3 "FLJ38547, GPR125, PGR21" ENSG00000152990 "Adhesion G protein-coupled receptor A3" Q8IWK6 4 22345071-22516066 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 54.5" "Cell type enhanced" "Detected in many" "Astrocytes: 373.6;Choroid plexus epithelial cells: 535.2;Endometrial ciliated cells: 350.0;Hepatocytes: 345.3;Myonuclei: 329.2;Pituitary stem cells: 665.2;Thymic myoid cells: 378.0" "Cell type enhanced" "Detected in all" "astrocyte: 471.8;choroid plexus epithelial cell: 445.8;ependymal cell: 333.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Mesothelial cells, Skin - Outer root sheath cells, Spleen - Endothelial cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008904 Uncertain "Intracellular and membrane" Receptor NA NA 390000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 39: Astrocytes - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 51: Secretory epithelial cells - Mixed function" 2 "HPA008904: " "unprognostic (1.17e-2)" "unprognostic (3.14e-1)" "unprognostic (2.67e-1)" "unprognostic (2.99e-3)" "unprognostic (1.16e-2)" "unprognostic (1.70e-1)" "unprognostic (3.53e-2)" "unprognostic (2.06e-1)" "unprognostic (1.69e-1)" "potential prognostic favorable (1.00e-4)" "unprognostic (2.18e-1)" "unprognostic (1.82e-2)" "unprognostic (3.12e-1)" "unprognostic (6.64e-3)" "unprognostic (1.34e-2)" "unprognostic (1.13e-1)" "unprognostic (7.82e-2)" "unprognostic (2.05e-1)" "unprognostic (6.31e-2)" "unprognostic (5.53e-2)" "unprognostic (2.08e-1)" "unprognostic (2.06e-1)" "unprognostic (5.77e-2)" "unprognostic (1.01e-1)" "unprognostic (2.01e-1)" "unprognostic (8.79e-2)" "unprognostic (1.68e-1)" "unprognostic (7.26e-3)" "unprognostic (1.09e-1)" ADGRB1 BAI1 ENSG00000181790 "Adhesion G protein-coupled receptor B1" O14514 8 142449430-142545009 "Cancer-related genes, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Innate immunity, Myogenesis, Neurogenesis, Phagocytosis" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 46.0" "Cell type enhanced" "Detected in some" "Astrocytes: 60.4;Bergmann glia: 100.8;Brain excitatory neurons: 42.2;Brain inhibitory neurons: 70.9;Epididymal principal cells: 19.8;Gonadotrophs: 20.5;Oligodendrocyte progenitor cells: 112.7;Other brain neurons: 29.3;Peritubular myoid cells: 19.2;Retinal horizontal cells: 84.1" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 7 "Glioblastoma Multiforme (TCGA): 21.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Smooth muscle cells, Pituitary gland - Gonadotropes, Skin - Hair cortex cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted in brain" Receptor NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 70: DU4475 - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" 10 "unprognostic (1.21e-1)" "unprognostic (6.49e-3)" "unprognostic (1.02e-1)" "unprognostic (3.47e-1)" "unprognostic (2.40e-2)" "unprognostic (8.31e-2)" "unprognostic (5.96e-2)" "unprognostic (3.02e-2)" "unprognostic (1.57e-1)" "unprognostic (3.44e-2)" "unprognostic (3.15e-1)" "unprognostic (2.33e-1)" ADGRB2 BAI2 ENSG00000121753 "Adhesion G protein-coupled receptor B2" O60241 1 31727117-31764893 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 74.7" "Cell type enhanced" "Detected in many" "Astrocytes: 22.1;Bergmann glia: 12.4;Brain excitatory neurons: 47.6;Brain inhibitory neurons: 40.1;Ependymal cells: 17.0;Gonadotrophs: 14.7;Late spermatids: 24.8;Oligodendrocyte progenitor cells: 34.6;Oligodendrocytes: 16.7;Other brain neurons: 20.0;Retinal amacrine cells: 22.8" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 4 "Glioblastoma Multiforme (TCGA): 40.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal medulla cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069175 Supported "Plasma membrane" "Intracellular and membrane" Receptor NA NA 13000 "Cluster 10: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 35: Neurons - Synaptic function & neurogenesis" 1 "Plasma membrane" "HPA069175: " "unprognostic (1.32e-2)" "unprognostic (1.16e-2)" "unprognostic (4.45e-2)" "unprognostic (3.88e-2)" "unprognostic (1.47e-1)" "unprognostic (2.18e-1)" "unprognostic (1.03e-1)" "unprognostic (3.50e-2)" "unprognostic (1.07e-3)" "unprognostic (6.46e-2)" "unprognostic (1.06e-3)" "unprognostic (3.96e-2)" "unprognostic (2.74e-3)" "unprognostic (5.70e-2)" "unprognostic (7.03e-2)" "unprognostic (1.08e-1)" "unprognostic (7.30e-2)" "unprognostic (1.48e-1)" "unprognostic (4.67e-2)" "unprognostic (1.58e-1)" "unprognostic (5.70e-2)" "unprognostic (2.19e-1)" "unprognostic (1.92e-1)" "unprognostic (8.13e-3)" "unprognostic (1.67e-2)" ADGRB3 "BAI3, KIAA0550" ENSG00000135298 "Adhesion G protein-coupled receptor B3" O60242 6 68635282-69390571 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 28.2;pituitary gland: 21.3" "Cell type enhanced" "Detected in many" "Astrocytes: 2909.0;Bergmann glia: 3658.5;Brain excitatory neurons: 4026.4;Brain inhibitory neurons: 3169.3;Corticotrophs: 1506.9;Lactotrophs: 1236.8;Oligodendrocyte progenitor cells: 2893.2;Oligodendrocytes: 1137.4;Other brain neurons: 1914.8;Pituicytes/FSCs: 1372.8;Retinal bipolar cells: 1092.5;Schwann cells: 1371.3;Somatotrophs: 1068.3" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in single" 12 "Glioblastoma Multiforme (TCGA): 10.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Neuroblastoma: 12.1" "Breast - Endothelial cells, Colon - Enteric glia cells, Liver - Hepatic stellate cells, Lung - Fibroblasts_1, Prostate - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 34: Non-specific - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 35: Neurons - Synaptic function & neurogenesis" 5 "unprognostic (5.55e-2)" "unprognostic (2.58e-2)" ADGRD1 "DKFZp434B1272, GPR133, PGR25" ENSG00000111452 "Adhesion G protein-coupled receptor D1" Q6QNK2 12 130953907-131141469 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 54.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 133.4;Cardiomyocytes: 196.1;Decidual stromal cells: 74.8;Endometrial stromal cells: 135.6;Epicardial cells: 393.4;Fibro-adipogenic progenitors: 142.3;Fibroblasts: 139.3;Late spermatids: 125.3;Mesothelial cells: 262.9;Thymic myoid cells: 116.9;Transitional alveolar cells: 121.1" "Cell type enhanced" "Detected in many" "fibroblast: 194.7;pericyte: 161.1" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 11.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 2.0;intermediate monocyte: 2.3;myeloid DC: 1.1;non-classical monocyte: 1.9" "Group enriched" "Detected in many" 6 "dendritic cells: 1.1;monocytes: 2.3" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Kidney - Fibroblasts, Pituitary gland - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Parietal cells" "Region enhanced" "Detected in some" "basal ganglia: 5.1" "Low region specificity" "Detected in all" "HPA042395, HPA076279" Uncertain Approved "Nucleoplasm,Nuclear speckles,Plasma membrane" NA NA 170000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 38: Sub-cortical - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 1 "Plasma membrane" "Nucleoplasm, Nuclear speckles" "HPA042395: , HPA076279: " "unprognostic (1.33e-1)" "unprognostic (9.78e-2)" "unprognostic (4.33e-2)" "unprognostic (4.17e-2)" "unprognostic (8.47e-3)" "unprognostic (2.29e-1)" "potential prognostic unfavorable (6.49e-5)" "potential prognostic favorable (3.40e-4)" "unprognostic (2.75e-2)" "unprognostic (4.86e-3)" "unprognostic (2.19e-1)" "unprognostic (1.35e-1)" "unprognostic (4.84e-2)" "unprognostic (8.06e-2)" "unprognostic (1.01e-1)" "unprognostic (4.72e-2)" "unprognostic (4.16e-3)" "unprognostic (1.47e-2)" "unprognostic (1.14e-2)" "unprognostic (1.89e-1)" "unprognostic (4.53e-2)" "unprognostic (1.36e-1)" ADGRD2 "GPR144, PGR24" ENSG00000180264 "Adhesion G protein-coupled receptor D2" 9 124450451-124478589 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "seminal vesicle: 2.1" "Cell type enhanced" "Detected in some" "Corticotrophs: 21.2;Early spermatids: 36.8;Ependymal cells: 66.5;Epididymal basal cells: 221.4;Gonadotrophs: 19.2;Late spermatids: 167.6;Medullary thymic epithelial cells: 55.2" "Cell type enriched" "Detected in some" 6 "ependymal cell: 126.1" "Not detected" "Not detected" "Region enhanced" "Detected in some" "medulla oblongata: 5.5;spinal cord: 6.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 1.0;Gallbladder cancer: 1.1" "Pituitary gland - Corticotropes, Testis - Early spermatids, Testis - Late spermatids" "Region enhanced" "Detected in single" "midbrain: 1.6" NA NA "Cluster 58: Skin - Keratinization" "Cluster 43: Hindbrain - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" ADGRE1 "EMR1, TM7LN3" ENSG00000174837 "Adhesion G protein-coupled receptor E1" Q14246 19 6887566-6940459 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Adaptive immunity, Immunity" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.4;lymphoid tissue: 13.9" "Cell type enhanced" "Detected in some" "Early spermatids: 18.2;Kupffer cells: 48.2;Macrophages: 13.2;monocytes: 41.6;Neutrophil progenitors: 48.1;Neutrophils: 74.2;Platelets: 18.3" "Cell type enhanced" "Detected in some" "leukocyte: 9.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 166.6;eosinophil: 325.5" "Group enriched" "Detected in many" 18 "granulocytes: 325.5;monocytes: 105.3" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 13.1" "Pituitary gland - Macrophages, Spleen - Macrophages" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA052809 Uncertain NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" "HPA052809: " "unprognostic (1.72e-1)" "unprognostic (1.93e-1)" "unprognostic (6.46e-2)" "unprognostic (1.25e-1)" "potential prognostic unfavorable (5.88e-5)" "unprognostic (5.74e-3)" "unprognostic (3.81e-1)" "unprognostic (1.47e-1)" "unprognostic (3.05e-1)" "unprognostic (3.73e-2)" "unprognostic (1.33e-1)" "unprognostic (9.61e-2)" ADGRE2 "CD312, EMR2" ENSG00000127507 "Adhesion G protein-coupled receptor E2" Q9UHX3 19 14732392-14778560 "CD markers, Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Cell adhesion, Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 18.3" "Cell type enriched" "Detected in many" 4 "Neutrophils: 1736.7" "Cell type enhanced" "Detected in some" "leukocyte: 43.5;oligodendrocyte: 21.8;pericyte: 23.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 70.2;eosinophil: 74.8;intermediate monocyte: 46.9;neutrophil: 55.8;non-classical monocyte: 90.2" "Group enriched" "Detected in many" 9 "granulocytes: 74.8;monocytes: 90.2" "Cancer enhanced" "Detected in many" "Leukemia: 7.7" "Lung - Neutrophils_2" "Low region specificity" "Detected in many" HPA055200 Uncertain Vesicles,Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 24: Neutrophils - Innate immunity signal integration" 18 Vesicles Cytosol "HPA055200: " "unprognostic (2.68e-1)" "unprognostic (7.32e-2)" "potential prognostic unfavorable (6.87e-4)" "unprognostic (1.26e-1)" "unprognostic (1.66e-1)" "unprognostic (4.26e-2)" "unprognostic (4.01e-1)" "unprognostic (1.66e-1)" "unprognostic (1.06e-1)" "unprognostic (1.31e-1)" "unprognostic (3.19e-1)" "unprognostic (6.61e-2)" "unprognostic (7.02e-3)" "unprognostic (1.14e-3)" "unprognostic (5.34e-2)" "unprognostic (1.26e-2)" "unprognostic (1.77e-1)" "unprognostic (2.34e-1)" "unprognostic (3.50e-3)" "unprognostic (7.29e-2)" "unprognostic (2.15e-1)" "unprognostic (7.23e-3)" "unprognostic (6.68e-2)" "unprognostic (5.94e-2)" "unprognostic (6.74e-3)" "unprognostic (1.91e-1)" "unprognostic (3.25e-1)" ADGRE3 EMR3 ENSG00000131355 "Adhesion G protein-coupled receptor E3" Q9BY15 19 14619117-14690027 "G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 3.0;lymphoid tissue: 5.7" "Cell type enriched" "Detected in many" 11 "Neutrophils: 369.9" "Cell type enhanced" "Detected in some" "leukocyte: 8.0" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.1" "Group enriched" "Detected in many" 7 "basophil: 282.8;eosinophil: 510.3;neutrophil: 491.6" "Lineage enriched" "Detected in many" 8 "granulocytes: 510.3" "Cancer enriched" "Detected in single" 7 "Leukemia: 1.0" "Adipose visceral - Neutrophils, Minor Salivary Gland - Minor salivary glandular cells" "Not detected" "Not detected" HPA015638 Uncertain "Secreted to blood" Receptor NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 49: HMC-1 - Innate immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" "HPA015638: " "unprognostic (5.26e-2)" "unprognostic (4.13e-1)" "unprognostic (2.49e-1)" "unprognostic (2.34e-1)" "unprognostic (1.77e-1)" ADGRE5 "CD97, TM7LN1" ENSG00000123146 "Adhesion G protein-coupled receptor E5" P48960 19 14380501-14408725 "CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cell adhesion" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 165.3;bone marrow: 200.1" "Cell type enhanced" "Detected in many" "B-cells: 343.2;Hematopoietic stem cells: 504.1;Innate lymphoid cells: 524.8;Kupffer cells: 552.4;Mast cells: 362.4;Monocyte progenitors: 794.4;monocytes: 463.7;Neutrophil progenitors: 819.9;Neutrophils: 1296.2;NK-cells: 656.2;T-cells: 510.8" "Cell type enriched" "Detected in many" 7 "leukocyte: 256.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013707 Enhanced Approved "Golgi apparatus,Plasma membrane" "Secreted to blood" Receptor NA Yes 10000000 3300000 "Cluster 7: Non-specific - Innate immune response" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 11: White matter - Signal transduction" "Cluster 23: Non-specific - Transcription" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 4 "Plasma membrane" "Golgi apparatus" "HPA013707: " "unprognostic (2.90e-1)" "unprognostic (5.56e-1)" "unprognostic (9.50e-2)" "unprognostic (2.00e-1)" "unprognostic (6.93e-3)" "unprognostic (8.66e-2)" "potential prognostic unfavorable (1.02e-4)" "unprognostic (3.26e-2)" "unprognostic (6.14e-3)" "unprognostic (1.08e-2)" "unprognostic (9.06e-2)" "unprognostic (8.73e-2)" "potential prognostic unfavorable (3.63e-5)" "unprognostic (2.30e-1)" "unprognostic (3.54e-1)" "potential prognostic unfavorable (7.31e-4)" "unprognostic (3.01e-1)" "unprognostic (1.19e-2)" "unprognostic (5.29e-1)" "unprognostic (8.35e-3)" "unprognostic (6.34e-2)" "unprognostic (2.40e-1)" "unprognostic (7.05e-2)" "potential prognostic favorable (2.47e-5)" "unprognostic (1.14e-1)" "unprognostic (5.49e-2)" "unprognostic (5.05e-2)" "unprognostic (4.08e-2)" "unprognostic (6.02e-2)" ADGRF1 "GPR110, hGPCR36, PGR19" ENSG00000153292 "Adhesion G protein-coupled receptor F1" Q5T601 6 46997708-47042350 "G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 17.0;kidney: 27.1;urinary bladder: 39.7" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 226.2;Endometrial glandular cells: 143.5;Esophageal apical cells: 614.2;Ocular epithelial cells: 211.0;Papillary tip epithelial cells: 221.2;Prostatic club cells: 303.8;Prostatic hillock cells: 276.4;Renal collecting duct intercalated cells: 696.2;Renal collecting duct principal cells: 160.2;Respiratory ionocytes: 142.2;Salivary duct cells: 274.7;Urothelial cells: 856.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "pancreatic cancer: 62.2" "Lung - Alveolar cells type 2, Pancreas - Ductal cells, Prostate - Urothelial cells, Stomach - Gastric mucous cells, Testis - Sertoli cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA038438 Approved "Secreted - unknown location" Receptor NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 69: Urothelial cells - Basic cellular functions" 16 "HPA038438: " "unprognostic (9.40e-2)" "unprognostic (3.00e-1)" "unprognostic (7.51e-2)" "unprognostic (1.62e-3)" "unprognostic (5.90e-2)" "unprognostic (1.39e-1)" "unprognostic (3.08e-1)" "unprognostic (7.70e-2)" "unprognostic (6.94e-3)" "unprognostic (1.95e-2)" "unprognostic (9.83e-2)" "unprognostic (7.27e-3)" "unprognostic (1.22e-1)" "unprognostic (8.44e-3)" "unprognostic (4.09e-2)" "unprognostic (1.17e-1)" "unprognostic (2.47e-1)" "unprognostic (1.94e-1)" "unprognostic (1.36e-1)" "unprognostic (1.06e-2)" ADGRF3 "GPR113, hGPCR37, PGR23" ENSG00000173567 "Adhesion G protein-coupled receptor F3" Q8IZF5 2 26308173-26346817 "G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 106.8;Early spermatids: 40.3;Epicardial cells: 63.7;Late primary spermatocytes: 29.6;Late spermatids: 52.9" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Kidney - Ascending Loop of Henle cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA044500 Uncertain Approved "Golgi apparatus,Cytosol" NA NA "Cluster 55: Non-specific - Transcription" "Cluster 6: Leukemia - Signal transduction" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" "Golgi apparatus" Cytosol "HPA044500: " ADGRF4 "FLJ38076, GPR115, PGR18" ENSG00000153294 "Adhesion G protein-coupled receptor F4" Q8IZF3 6 47685864-47722021 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 17.5;skin 1: 36.6" "Cell type enhanced" "Detected in some" "Colonocytes: 16.5;Esophageal apical cells: 92.3;Esophageal basal cells: 19.6;Esophageal suprabasal cells: 67.4;Extravillous trophoblasts: 24.1;Ocular epithelial cells: 124.7;Suprabasal keratinocytes: 52.1;Urothelial cells: 48.7" "Cell type enriched" "Detected in some" 5 "cerebellar inhibitory: 6.9" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 12.4" "Region enriched" "Detected in single" 5 "hypothalamus: 4.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 16.7" "Prostate - Urothelial cells" "Low region specificity" "Detected in some" "Region enhanced" "Detected in single" "spinal cord: 2.0" "HPA007131, HPA007158" Enhanced Approved Mitochondria NA NA "Cluster 58: Skin - Keratinization" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" Mitochondria "HPA007131: , HPA007158: " "unprognostic (1.43e-1)" "unprognostic (2.96e-2)" "unprognostic (4.53e-1)" "unprognostic (7.65e-2)" "unprognostic (2.71e-2)" "potential prognostic unfavorable (3.86e-5)" "unprognostic (7.93e-3)" "unprognostic (2.55e-2)" "unprognostic (2.61e-3)" "validated prognostic unfavorable (3.48e-4)" "validated prognostic unfavorable (4.67e-4)" "unprognostic (1.05e-1)" "unprognostic (1.48e-1)" "unprognostic (1.63e-1)" "unprognostic (1.11e-3)" ADGRF5 "DKFZp564O1923, GPR116, KIAA0758" ENSG00000069122 "Adhesion G protein-coupled receptor F5" Q8IZF2 6 46852522-46954943 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 99.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 337.4;Alveolar cells type 2: 537.3;Epididymal clear cells: 165.3;Lymphatic endothelial cells: 138.3;Pericytes: 337.3;Renal collecting duct intercalated cells: 1673.4;Respiratory ionocytes: 312.4;Transitional alveolar cells: 347.7;Vascular endothelial cells: 401.5" "Group enriched" "Detected in many" 6 "endothelial cell: 767.0;pericyte: 289.3" "Group enriched" "Detected in all" 4 "Kidney Chromophobe (TCGA): 102.0;Kidney Renal Clear Cell Carcinoma (TCGA): 58.9;Lung Adenocarcinoma (TCGA): 61.5;Thyroid Carcinoma (TCGA): 28.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 11.7;pancreatic cancer: 6.7;Sarcoma: 6.2" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Spleen - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 37000000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 1 "unprognostic (3.31e-1)" "unprognostic (5.54e-2)" "unprognostic (1.47e-1)" "unprognostic (8.74e-2)" "unprognostic (9.18e-2)" "unprognostic (1.21e-1)" "unprognostic (1.31e-1)" "unprognostic (3.27e-2)" "unprognostic (1.25e-1)" "validated prognostic favorable (1.37e-9)" "validated prognostic favorable (2.41e-4)" "potential prognostic unfavorable (9.77e-4)" "unprognostic (5.60e-2)" "unprognostic (2.86e-3)" "unprognostic (2.78e-1)" "unprognostic (9.24e-3)" "unprognostic (7.12e-2)" "unprognostic (2.36e-1)" "unprognostic (1.91e-3)" "unprognostic (1.36e-1)" "unprognostic (5.71e-2)" "unprognostic (4.65e-2)" "unprognostic (1.26e-2)" "unprognostic (2.71e-2)" "unprognostic (4.46e-2)" "unprognostic (6.48e-3)" "unprognostic (1.26e-1)" "unprognostic (1.56e-1)" "unprognostic (5.10e-2)" ADGRG1 "GPR56, TM7LN4, TM7XN1" ENSG00000205336 "Adhesion G protein-coupled receptor G1" Q9Y653 16 57610652-57665580 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Differentiation, Neurogenesis" "Developmental protein, G-protein coupled receptor, Heparin-binding, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 202.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 276.2;Melanocytes: 227.3;Migrating cytotrophoblasts: 201.2;Syncytiotrophoblasts: 218.1" "Cell type enhanced" "Detected in many" "astrocyte: 150.0;central nervous system macrophage: 175.9;oligodendrocyte precursor cell: 144.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 160.5" "Lineage enriched" "Detected in many" 5 "T-cells: 160.5" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Heart muscle - Endothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Endothelial cells, Spleen - NK-cells (Spleen), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046065 Uncertain "Secreted to blood" Receptor NA NA 8300 "Cluster 24: Non-specific - Transcription" "Cluster 33: Thyroid gland - Tissue development" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 1 "HPA046065: " "unprognostic (1.71e-1)" "potential prognostic unfavorable (5.40e-4)" "unprognostic (2.60e-3)" "unprognostic (1.07e-1)" "unprognostic (1.02e-1)" "unprognostic (3.10e-2)" "unprognostic (1.84e-2)" "unprognostic (8.35e-3)" "unprognostic (2.48e-1)" "validated prognostic favorable (5.42e-12)" "validated prognostic favorable (2.65e-5)" "unprognostic (1.42e-2)" "unprognostic (2.97e-1)" "unprognostic (3.07e-1)" "unprognostic (3.04e-1)" "unprognostic (1.47e-2)" "unprognostic (2.03e-1)" "unprognostic (1.46e-1)" "unprognostic (1.49e-1)" "unprognostic (5.93e-2)" "unprognostic (2.25e-1)" "unprognostic (2.24e-1)" "unprognostic (7.96e-3)" "unprognostic (2.35e-2)" "unprognostic (1.87e-1)" "unprognostic (2.71e-1)" "unprognostic (1.20e-1)" "unprognostic (1.08e-1)" "unprognostic (2.12e-1)" ADGRG2 "EDDM6, GPR64, HE6, TM7LN2" ENSG00000173698 "Adhesion G protein-coupled receptor G2" Q8IZP9 X 18989307-19122637 "Disease related genes, G-protein coupled receptors, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "epididymis: 1159.4" "Cell type enhanced" "Detected in many" "Epididymal efferent duct absorptive cells: 887.7;Epididymal efferent duct ciliated cells: 400.4;Epididymal principal cells: 2215.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 14.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 16.6" "Adrenal gland - Fibroblasts, Breast - Adipocytes (Breast), Colon - Colon enteroendocrine cells, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA001478, HPA050029" Enhanced Approved "Plasma membrane,Cytosol" NA NA 2200000 "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 29: Forebrain - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" "Plasma membrane, Cytosol" "HPA001478: , HPA050029: " "unprognostic (1.62e-1)" "unprognostic (3.32e-3)" "unprognostic (2.23e-1)" "unprognostic (1.07e-1)" "unprognostic (2.68e-1)" "potential prognostic unfavorable (5.69e-9)" "potential prognostic unfavorable (9.30e-4)" "unprognostic (2.11e-1)" "unprognostic (4.34e-2)" "unprognostic (3.35e-1)" "unprognostic (2.64e-1)" "unprognostic (3.63e-2)" "unprognostic (2.45e-2)" "unprognostic (1.79e-1)" "unprognostic (2.84e-1)" "unprognostic (1.81e-1)" "unprognostic (2.53e-1)" "unprognostic (2.72e-1)" "unprognostic (8.69e-2)" ADGRG3 "GPR97, Pb99, PGR26" ENSG00000182885 "Adhesion G protein-coupled receptor G3" Q86Y34 16 57668277-57689378 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 139.0;lymphoid tissue: 34.8" "Group enriched" "Detected in some" 16 "Neutrophil progenitors: 444.3;Neutrophils: 1721.8" "Cell type enhanced" "Detected in single" "leukocyte: 1.3" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in some" 5 "cerebral cortex: 22.7" "Immune cell enhanced" "Detected in some" "eosinophil: 142.5;neutrophil: 170.3" "Lineage enriched" "Detected in many" 5 "granulocytes: 170.3" "Group enriched" "Detected in some" 9 "Leukemia: 2.4;lymphoma: 3.1" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophils_2, Pituitary gland - Neutrophils, Skeletal muscle - Neutrophils, Skin - Macrophages, Spleen - Neutrophils_2, Stomach - Neutrophils" "Not detected" "Not detected" "Not detected" "Not detected" HPA040469 Uncertain NA NA 3500000 "Cluster 21: Neutrophils - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 9 "HPA040469: " "unprognostic (2.19e-1)" "unprognostic (5.79e-2)" "potential prognostic unfavorable (2.27e-4)" "unprognostic (4.26e-3)" "unprognostic (5.67e-2)" "unprognostic (1.77e-1)" "unprognostic (2.34e-1)" "unprognostic (2.39e-1)" "unprognostic (6.34e-2)" ADGRG4 "GPR112, PGR17, RP1-299I16" ENSG00000156920 "Adhesion G protein-coupled receptor G4" Q8IZF6 X 136300963-136416890 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 1.1;intestine: 2.3;retina: 1.1" "Group enriched" "Detected in some" 10 "Neuroendocrine cells: 127.5;Retinal horizontal cells: 68.1" "Cell type enriched" "Detected in single" 6 "hippocampal dentate gyrus: 3.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA035324 Uncertain NA NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 72: Neuronal - Signal transduction" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" "HPA035324: " ADGRG5 "GPR114, PGR27" ENSG00000159618 "Adhesion G protein-coupled receptor G5" Q8IZF4 16 57542643-57591681 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 3.7;lymphoid tissue: 9.9" "Cell type enhanced" "Detected in some" "B-cells: 28.1;Innate lymphoid cells: 25.3;Microglia: 34.8;NK-cells: 137.6;pDCs: 127.7;Plasma cells: 41.2;T-cells: 30.8;Thymocytes: 71.1" "Group enriched" "Detected in some" 62 "central nervous system macrophage: 48.5;leukocyte: 88.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "eosinophil: 126.2" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Leukemia: 11.0;lymphoma: 6.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Colon - T-cells, Heart muscle - T-cells, Minor Salivary Gland - Plasma cells, Prostate - T-cells, Testis - Spermatogonia, Thyroid gland - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA007133 Enhanced Approved "Nucleoplasm,Nuclear membrane,Vesicles" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" "Nuclear membrane, Vesicles" Nucleoplasm "HPA007133: " "unprognostic (2.86e-2)" "unprognostic (2.73e-1)" "unprognostic (7.36e-2)" "unprognostic (1.00e-3)" "unprognostic (1.26e-1)" "unprognostic (1.78e-1)" "unprognostic (2.91e-3)" "unprognostic (1.79e-1)" "unprognostic (1.73e-1)" "unprognostic (7.50e-2)" "unprognostic (1.85e-1)" ADGRG6 "FLJ14937, GPR126" ENSG00000112414 "Adhesion G protein-coupled receptor G6" Q86SQ4 6 142301854-142446266 "Disease related genes, G-protein coupled receptors, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 67.2;placenta: 44.6" "Cell type enhanced" "Detected in many" "Hematopoietic stem cells: 229.0;Hepatocytes: 292.0;Kupffer cells: 110.7;Mesothelial cells: 144.5;Mucous neck cells: 114.7;Papillary tip epithelial cells: 224.3;Prostatic club cells: 110.8;Salivary ionocytes: 116.2;Suprabasal keratinocytes: 143.3;Tuft cells: 299.7;Urothelial cells: 193.3" "Cell type enhanced" "Detected in many" "endothelial cell: 268.7;LAMP5-LHX6 and Chandelier: 70.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Adrenal gland - Macrophages, Colon - Enteric glia cells, Liver - Hepatocytes, Spleen - Macrophages, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA017346 Approved NA NA 20000000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" "HPA017346: " "unprognostic (1.05e-1)" "unprognostic (1.48e-2)" "unprognostic (5.77e-3)" "unprognostic (3.99e-2)" "unprognostic (5.93e-3)" "unprognostic (1.79e-3)" "unprognostic (5.31e-2)" "unprognostic (2.54e-1)" "unprognostic (3.96e-1)" "potential prognostic favorable (9.25e-4)" "unprognostic (2.96e-2)" "unprognostic (9.15e-2)" "unprognostic (1.68e-1)" "unprognostic (3.99e-3)" "unprognostic (4.81e-1)" "unprognostic (1.14e-2)" "unprognostic (4.11e-1)" "unprognostic (7.71e-2)" "unprognostic (5.02e-1)" "validated prognostic unfavorable (4.01e-6)" "validated prognostic unfavorable (6.89e-4)" "unprognostic (4.04e-1)" "unprognostic (1.09e-1)" "unprognostic (1.46e-1)" "unprognostic (1.56e-1)" "unprognostic (2.03e-1)" "unprognostic (1.90e-1)" "unprognostic (4.60e-2)" ADGRG7 "FLJ14454, GPR128" ENSG00000144820 "Adhesion G protein-coupled receptor G7" Q96K78 3 100609601-100695479 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "intestine: 40.4;liver: 23.1" "Cell type enhanced" "Detected in some" "Colonocytes: 22.0;Enteric stem cells: 13.8;Enteric transient amplifying cells: 29.7;Enterocytes: 135.5;Gastric progenitor cells: 24.4;Goblet cells: 41.5;Hepatocytes: 74.2;Paneth cells: 34.8;Smooth muscle cells: 13.0" "Cell type enhanced" "Detected in single" "hippocampal dentate gyrus: 1.7" "Cancer enhanced" "Detected in some" "Stomach Adenocarcinoma (TCGA): 6.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 1.8;Brain cancer: 1.3" "Colon - Colon enterocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA056451 Approved "Plasma membrane" NA NA "Cluster 77: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 1: Enterocytes - Absorption and Digestion" 3 "Plasma membrane" "HPA056451: " "unprognostic (2.10e-1)" "unprognostic (2.35e-1)" "unprognostic (1.19e-1)" "unprognostic (8.46e-2)" "unprognostic (2.93e-1)" "unprognostic (3.66e-1)" "unprognostic (3.65e-3)" "unprognostic (4.31e-2)" "unprognostic (3.25e-1)" "unprognostic (5.25e-2)" "unprognostic (1.75e-1)" ADGRL1 "CIRL1, KIAA0821, LEC2, LPHN1" ENSG00000072071 "Adhesion G protein-coupled receptor L1" O94910 19 14147743-14206187 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Autism spectrum disorder, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 70.4" "Cell type enhanced" "Detected in some" "Astrocytes: 41.8;Bergmann glia: 47.4;Brain excitatory neurons: 82.7;Brain inhibitory neurons: 82.4;Choroid plexus epithelial cells: 25.9;Distal convoluted tubule cells: 19.9;Ependymal cells: 31.7;Loop of henle epithelial cells: 19.8;Oligodendrocyte progenitor cells: 66.5;Oligodendrocytes: 39.8;Other brain neurons: 54.9;Podocytes: 20.6;Renal collecting duct intercalated cells: 21.0;Renal collecting duct principal cells: 22.1;Renal connecting tubule cells: 28.3;Tuft cells: 23.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037974 Uncertain NA NA 190000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 3 "HPA037974: " "unprognostic (1.03e-2)" "unprognostic (1.13e-2)" "unprognostic (7.21e-2)" "unprognostic (7.92e-2)" "unprognostic (1.51e-1)" "unprognostic (8.64e-2)" "unprognostic (5.90e-2)" "unprognostic (1.26e-1)" "unprognostic (1.16e-1)" "unprognostic (1.89e-1)" "unprognostic (2.02e-1)" "unprognostic (6.29e-2)" "unprognostic (2.09e-2)" "unprognostic (3.71e-2)" "unprognostic (5.92e-2)" "unprognostic (9.57e-2)" "potential prognostic favorable (2.09e-4)" "unprognostic (6.57e-2)" "unprognostic (2.02e-2)" "potential prognostic favorable (4.58e-4)" "unprognostic (1.01e-1)" "unprognostic (1.33e-1)" "unprognostic (1.68e-1)" "unprognostic (3.25e-1)" "unprognostic (1.51e-1)" "unprognostic (4.20e-2)" "unprognostic (4.59e-2)" "unprognostic (7.12e-3)" "unprognostic (8.25e-2)" ADGRL2 "CIRL2, KIAA0786, LEC1, LPHH1, LPHN2" ENSG00000117114 "Adhesion G protein-coupled receptor L2" O95490 1 81306147-81993932 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 517.6;Brain excitatory neurons: 517.2;Distal convoluted tubule cells: 521.7;Esophageal apical cells: 795.0;Lacrimal acinar cells: 487.3;Pituicytes/FSCs: 781.0;Pituitary stem cells: 1366.8;Retinal bipolar cells: 1615.7" "Cell type enhanced" "Detected in all" "mammillary body: 1846.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Endothelial cells, Minor Salivary Gland - Minor salivary gland ductal cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Prostate - Fibroblasts, Stomach - Endothelial cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043447 Approved "Plasma membrane" NA NA 620000 "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 53: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 2 "Plasma membrane" "HPA043447: " "unprognostic (1.53e-1)" "unprognostic (2.03e-2)" "potential prognostic unfavorable (3.37e-4)" "unprognostic (4.73e-2)" "unprognostic (5.65e-2)" "unprognostic (2.41e-1)" "unprognostic (2.15e-2)" "unprognostic (2.35e-1)" "unprognostic (7.70e-2)" "potential prognostic favorable (1.66e-4)" "unprognostic (1.16e-3)" "unprognostic (3.88e-2)" "potential prognostic unfavorable (4.17e-5)" "unprognostic (5.38e-2)" "unprognostic (2.93e-1)" "unprognostic (6.74e-2)" "unprognostic (1.79e-1)" "unprognostic (3.48e-1)" "unprognostic (2.40e-1)" "unprognostic (9.32e-2)" "unprognostic (1.65e-2)" "unprognostic (1.26e-1)" "unprognostic (2.85e-1)" "unprognostic (3.60e-2)" "unprognostic (1.13e-1)" "potential prognostic unfavorable (3.09e-4)" "unprognostic (1.39e-1)" "unprognostic (3.46e-2)" "unprognostic (2.19e-2)" ADGRL3 "KIAA0768, LEC3, LPHN3" ENSG00000150471 "Adhesion G protein-coupled receptor L3" Q9HAR2 4 61200326-62078335 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 14.9;brain: 23.3" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 684.2;Astrocytes: 1637.4;Bergmann glia: 4935.9;Brain excitatory neurons: 1494.7;Brain inhibitory neurons: 1762.9;Müller glia: 630.4;Oligodendrocyte progenitor cells: 3266.2;Oligodendrocytes: 1056.3;Other brain neurons: 1206.9;Pituicytes/FSCs: 672.8;Retinal amacrine cells: 1083.7;Schwann cells: 630.3;Sertoli cells: 714.2" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 8 "Glioblastoma Multiforme (TCGA): 22.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 8.0" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Colon - Enteric glia cells, Liver - Hepatic stellate cells, Skin - Outer root sheath cells, Spleen - Smooth muscle cells, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015027, HPA015762, CAB022698" Uncertain NA NA 14000 "Cluster 73: Brain - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 1 "CAB022698: , HPA015027: , HPA015762: " "unprognostic (1.33e-1)" "unprognostic (1.48e-1)" "unprognostic (1.35e-1)" "potential prognostic favorable (9.32e-4)" "unprognostic (8.33e-2)" "potential prognostic favorable (1.28e-4)" "unprognostic (3.04e-3)" "unprognostic (1.04e-1)" "unprognostic (2.22e-2)" "unprognostic (3.36e-2)" "unprognostic (2.05e-1)" "unprognostic (7.01e-2)" "unprognostic (1.13e-2)" "unprognostic (3.68e-2)" "unprognostic (8.58e-3)" "unprognostic (8.72e-2)" "unprognostic (3.90e-2)" ADGRL4 "ELTD1, ETL" ENSG00000162618 "Adhesion G protein-coupled receptor L4" Q9HBW9 1 78889764-79282124 "G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 64.3" "Cell type enriched" "Detected in many" 5 "Vascular endothelial cells: 743.2" "Cell type enriched" "Detected in many" 5 "endothelial cell: 529.5" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 52.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Sarcoma: 12.2;thyroid cancer: 15.1" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Pancreas - Endothelial cells, Pituitary gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Spleen - Endothelial cells, Stomach - Endothelial cells, Thyroid gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025229 Supported NA NA 5700000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "HPA025229: " "unprognostic (1.22e-2)" "unprognostic (7.61e-2)" "unprognostic (1.99e-1)" "unprognostic (5.15e-2)" "unprognostic (1.36e-1)" "unprognostic (1.74e-1)" "unprognostic (2.33e-2)" "unprognostic (1.11e-2)" "unprognostic (1.12e-1)" "potential prognostic favorable (1.37e-8)" "unprognostic (1.26e-3)" "potential prognostic unfavorable (5.10e-6)" "unprognostic (1.29e-1)" "unprognostic (3.06e-1)" "unprognostic (4.12e-2)" "unprognostic (1.17e-2)" "unprognostic (5.80e-2)" "unprognostic (9.91e-2)" "unprognostic (1.52e-2)" "unprognostic (5.20e-1)" "unprognostic (9.51e-2)" "unprognostic (1.05e-1)" "unprognostic (1.04e-2)" "unprognostic (5.62e-2)" "unprognostic (4.02e-3)" "unprognostic (3.87e-3)" "unprognostic (1.28e-1)" "unprognostic (1.80e-2)" "unprognostic (3.27e-2)" ADGRV1 "DKFZp761P0710, FEB4, GPR98, KIAA0686, MASS1, USH2C, VLGR1" ENSG00000164199 "Adhesion G protein-coupled receptor V1" Q8WXG9 5 90529344-91164437 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sensory transduction, Vision" "G-protein coupled receptor, Hydrolase, Receptor, Transducer" "Deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "adrenal gland: 494.7" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 788.9;Astrocytes: 3318.0;Choroid plexus epithelial cells: 1386.3;Cone photoreceptor cells: 931.6;Corticotrophs: 752.0;Ependymal cells: 1045.0;Lactotrophs: 664.5;Pituicytes/FSCs: 3636.3;Somatotrophs: 782.8;Thyrotrophs: 714.6" "Group enriched" "Detected in all" 5 "astrocyte: 2313.8;choroid plexus epithelial cell: 1103.6;ependymal cell: 936.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 26.4" "Adrenal gland - Adrenal cortex cells, Kidney - Ascending Loop of Henle cells, Liver - Hepatocytes, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067503 Approved Approved "Vesicles,Basal body" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 51: Neurons - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 1 Vesicles "Basal body" "HPA067503: " "unprognostic (1.72e-1)" "unprognostic (2.07e-2)" "unprognostic (2.15e-1)" "unprognostic (1.24e-1)" "unprognostic (1.41e-2)" "unprognostic (1.11e-2)" "unprognostic (3.07e-1)" "unprognostic (4.12e-1)" "potential prognostic favorable (7.03e-12)" "unprognostic (2.78e-2)" "unprognostic (5.07e-2)" "potential prognostic favorable (3.34e-4)" "unprognostic (1.63e-2)" "unprognostic (5.61e-2)" "unprognostic (1.17e-1)" "unprognostic (3.43e-1)" "unprognostic (1.41e-3)" "potential prognostic unfavorable (7.97e-4)" "unprognostic (7.01e-3)" "unprognostic (4.07e-2)" "potential prognostic unfavorable (6.75e-4)" "potential prognostic unfavorable (1.08e-4)" "unprognostic (1.03e-1)" "unprognostic (6.11e-2)" "unprognostic (1.78e-1)" ADH1A ADH1 ENSG00000187758 "Alcohol dehydrogenase 1A (class I), alpha polypeptide" P07327 4 99276369-99291003 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 304 "liver: 2559.5" "Cell type enriched" "Detected in some" 17 "Hepatocytes: 243.2" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 229 "Liver Hepatocellular Carcinoma (TCGA): 407.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Adipocytes (Breast), Liver - Hepatocytes, Minor Salivary Gland - Adipocytes (Minor salivary gland)" "CAB009562, HPA047814, HPA060902" Enhanced Approved "Nucleoplasm,Plasma membrane,Primary cilium,Primary cilium transition zone,Basal body,Cytosol" NA NA 32000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 93: Hepatocytes - Bile production & excretion" "Plasma membrane, Cytosol" "Nucleoplasm, Primary cilium, Primary cilium transition zone, Basal body" "CAB009562: , HPA047814: , HPA060902: " "potential prognostic favorable (1.95e-4)" "unprognostic (2.75e-3)" "unprognostic (1.50e-3)" "unprognostic (3.22e-2)" ADH1B ADH2 ENSG00000196616 "Alcohol dehydrogenase 1B (class I), beta polypeptide" P00325 4 99304971-99352760 "Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 1408.8;liver: 5476.4" "Cell type enriched" "Detected in many" 5 "Hepatocytes: 5446.8" "Group enriched" "Detected in some" 39 "fibroblast: 44.1;pericyte: 47.6;vascular associated smooth muscle cell: 15.1" "Cancer enriched" "Detected in many" 27 "Liver Hepatocellular Carcinoma (TCGA): 832.6" "Region enhanced" "Detected in many" "choroid plexus: 24.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Fibroblasts, Breast - Adipocytes (Breast), Kidney - Fibroblasts, Liver - Hepatocytes, Pancreas - Fibroblasts, Spleen - Fibroblasts_2, Testis - Endothelial cells" "HPA047814, HPA060902" Supported Approved "Nucleoplasm,Plasma membrane,Primary cilium,Primary cilium transition zone,Basal body,Cytosol" NA NA 41000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 8: Immune cells - Immune response" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 1 "Plasma membrane, Cytosol" "Nucleoplasm, Primary cilium, Primary cilium transition zone, Basal body" "HPA047814: , HPA060902: " "unprognostic (1.36e-2)" "unprognostic (5.62e-2)" "potential prognostic favorable (9.38e-5)" "unprognostic (4.06e-2)" "unprognostic (1.40e-1)" "unprognostic (1.17e-1)" "unprognostic (9.45e-2)" "unprognostic (2.29e-1)" "potential prognostic unfavorable (1.19e-4)" "validated prognostic favorable (6.15e-4)" "validated prognostic favorable (6.43e-4)" "potential prognostic favorable (2.37e-4)" "unprognostic (2.02e-2)" "unprognostic (8.00e-3)" "unprognostic (8.33e-2)" "unprognostic (9.62e-3)" "unprognostic (9.31e-2)" "unprognostic (2.70e-2)" "unprognostic (3.20e-1)" "unprognostic (2.58e-1)" "unprognostic (1.16e-1)" "unprognostic (1.86e-1)" "unprognostic (7.62e-2)" "unprognostic (1.95e-3)" "unprognostic (4.10e-1)" "unprognostic (1.36e-1)" "unprognostic (3.91e-3)" ADH1C ADH3 ENSG00000248144 "Alcohol dehydrogenase 1C (class I), gamma polypeptide" P00326 4 99336497-99352746 "Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 21 "intestine: 562.7;liver: 1927.2;stomach 1: 538.9" "Cell type enhanced" "Detected in some" "Colonocytes: 55.7;Conjunctival goblet cells: 340.8;Enteric stem cells: 116.6;Enteric transient amplifying cells: 182.6;Foveolar cells: 86.5;Gastric chief cells: 52.4;Hepatocytes: 196.9;Mucous neck cells: 98.3;Paneth cells: 116.0;Respiratory basal cells: 60.8;Respiratory deuterosomal cells: 58.1;Respiratory secretory cells: 131.6" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 7 "Liver Hepatocellular Carcinoma (TCGA): 461.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 53.7" "Liver - Hepatocytes, Minor Salivary Gland - Minor salivary gland ductal cells" "HPA047814, HPA060902" Supported Approved "Nucleoplasm,Plasma membrane,Primary cilium,Primary cilium transition zone,Basal body,Cytosol" NA NA 19000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 7: Liver cancer - Metabolism" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 11 "Plasma membrane, Cytosol" "Nucleoplasm, Primary cilium, Primary cilium transition zone, Basal body" "HPA047814: , HPA060902: " "unprognostic (6.19e-2)" "unprognostic (1.26e-1)" "unprognostic (4.94e-2)" "unprognostic (6.65e-2)" "unprognostic (4.46e-3)" "unprognostic (1.12e-1)" "unprognostic (5.87e-2)" "unprognostic (8.09e-2)" "unprognostic (1.68e-1)" "unprognostic (1.40e-3)" "validated prognostic favorable (3.38e-4)" "validated prognostic favorable (5.73e-9)" "unprognostic (1.07e-2)" "unprognostic (1.08e-2)" "unprognostic (1.17e-2)" "unprognostic (8.99e-2)" "unprognostic (1.74e-1)" "unprognostic (2.19e-2)" "unprognostic (2.61e-1)" "unprognostic (1.59e-1)" "unprognostic (1.82e-1)" "unprognostic (9.15e-2)" "unprognostic (1.95e-1)" "unprognostic (2.53e-1)" ADH4 ADH-2 ENSG00000198099 "Alcohol dehydrogenase 4 (class II), pi polypeptide" P08319 4 99123657-99157792 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 31 "liver: 4815.9" "Cell type enriched" "Detected in many" 21 "Hepatocytes: 1345.1" "Cell type enhanced" "Detected in some" "ependymal cell: 5.8" "Cancer enriched" "Detected in some" 30 "Liver Hepatocellular Carcinoma (TCGA): 353.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 2.8" "Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA020525 Enhanced Uncertain Nucleoplasm,Cytosol NA NA 14000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 9: Non-specific - Receptor signaling" "Cluster 18: Liver cancer - Metabolism" "Cluster 93: Hepatocytes - Bile production & excretion" "Nucleoplasm, Cytosol" "HPA020525: " "unprognostic (4.38e-2)" "unprognostic (3.25e-1)" "potential prognostic unfavorable (4.88e-5)" "potential prognostic favorable (1.89e-6)" "unprognostic (1.20e-3)" "unprognostic (6.14e-2)" "unprognostic (6.74e-2)" "unprognostic (3.64e-2)" "unprognostic (3.93e-3)" ADH5 "ADH-3, ADHX, FDH, GSNOR" ENSG00000197894 "Alcohol dehydrogenase 5 (class III), chi polypeptide" P11766 4 99070978-99088801 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 348.5;Decidual stromal cells: 324.4;Extravillous trophoblasts: 348.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Macrophages, Prostate - Smooth muscle cells, Spleen - Fibroblasts_2, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA044578, HPA061919" Approved NA NA 5800000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 21: Non-specific - Metabolism" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 108: Fibroblasts - ECM organization" 3 "HPA044578: , HPA061919: " "unprognostic (1.24e-1)" "unprognostic (3.94e-1)" "unprognostic (1.75e-2)" "unprognostic (1.41e-1)" "unprognostic (2.32e-3)" "unprognostic (7.93e-3)" "unprognostic (9.26e-2)" "unprognostic (2.49e-1)" "unprognostic (4.45e-2)" "unprognostic (1.50e-1)" "validated prognostic favorable (1.66e-10)" "validated prognostic favorable (9.44e-4)" "unprognostic (1.57e-3)" "unprognostic (7.14e-2)" "unprognostic (9.96e-2)" "unprognostic (3.49e-2)" "unprognostic (1.21e-1)" "unprognostic (6.43e-2)" "unprognostic (2.91e-1)" "unprognostic (2.16e-1)" "unprognostic (1.54e-1)" "unprognostic (1.56e-2)" "unprognostic (1.89e-1)" "unprognostic (1.38e-1)" "unprognostic (7.42e-2)" "unprognostic (9.74e-2)" "unprognostic (1.54e-2)" "unprognostic (5.18e-3)" "unprognostic (1.67e-1)" "unprognostic (2.51e-2)" "unprognostic (1.03e-2)" ADH6 ADH-5 ENSG00000172955 "Alcohol dehydrogenase 6 (class V)" P28332 4 99202638-99219537 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "liver: 657.9" "Cell type enriched" "Detected in some" 11 "Hepatocytes: 436.7" "Cell type enhanced" "Detected in some" "ependymal cell: 2.8;vascular associated smooth muscle cell: 2.4" "Cancer enriched" "Detected in many" 17 "Liver Hepatocellular Carcinoma (TCGA): 89.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 6.3" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells" "Not detected" "Not detected" "HPA067946, HPA069081" Enhanced NA NA 1300000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 18: Liver cancer - Metabolism" "Cluster 93: Hepatocytes - Bile production & excretion" 1 "HPA067946: , HPA069081: " "unprognostic (3.18e-3)" "potential prognostic favorable (7.46e-4)" "unprognostic (4.80e-2)" "unprognostic (3.23e-1)" "potential prognostic favorable (1.94e-5)" "unprognostic (4.35e-2)" "unprognostic (1.48e-1)" "unprognostic (6.59e-3)" "unprognostic (9.76e-3)" "unprognostic (5.51e-3)" "unprognostic (3.93e-2)" "unprognostic (1.69e-2)" "unprognostic (1.20e-2)" "unprognostic (3.11e-2)" ADH7 ADH-4 ENSG00000196344 "Alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide" P40394 4 99412261-99435510 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "esophagus: 188.6" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 100.0;Esophageal apical cells: 168.9;Esophageal basal cells: 244.6;Esophageal suprabasal cells: 495.8;Ocular epithelial cells: 121.2;Respiratory basal cells: 199.1;Respiratory deuterosomal cells: 139.9;Respiratory secretory cells: 198.4;Suprabasal keratinocytes: 252.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 39.1;Head and Neck Squamous Cell Carcinoma (TCGA): 43.1;Lung Squamous Cell Carcinoma (TCGA): 95.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "Esophageal cancer: 32.8;Gallbladder cancer: 101.9" "Liver - Hepatocytes, Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA039695 Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" "HPA039695: " "unprognostic (2.20e-1)" "unprognostic (5.83e-2)" "unprognostic (5.28e-2)" "unprognostic (6.39e-3)" "unprognostic (5.31e-2)" "unprognostic (6.57e-3)" "unprognostic (2.31e-2)" "unprognostic (6.21e-2)" "unprognostic (1.57e-1)" ADHFE1 FLJ32430 ENSG00000147576 "Alcohol dehydrogenase iron containing 1" Q8IWW8 8 66432492-66468907 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 30.4;skeletal muscle: 28.8;tongue: 29.3" "Cell type enhanced" "Detected in some" "Astrocytes: 80.2;Bergmann glia: 92.2;Choroid plexus epithelial cells: 66.8;Distal convoluted tubule cells: 50.5;Ependymal cells: 42.8;Loop of henle epithelial cells: 50.7;Oligodendrocyte progenitor cells: 26.5;Oligodendrocytes: 20.5;Papillary tip epithelial cells: 20.2;Podocytes: 48.8;Proximal tubule cells: 63.9;Renal collecting duct intercalated cells: 35.3;Renal collecting duct principal cells: 26.9;Renal connecting tubule cells: 41.6" "Cell type enhanced" "Detected in all" "astrocyte: 87.6;Bergmann glia: 92.9" "Cancer enhanced" "Detected in some" "Liver Hepatocellular Carcinoma (TCGA): 5.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Adipocytes (Subcutaneous), Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA023062 Enhanced Approved Vesicles NA NA "Cluster 76: Non-specific - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 28: Astrocytes - Homeostasis & neuron support" Vesicles "HPA023062: " "unprognostic (8.52e-2)" "unprognostic (6.64e-2)" "unprognostic (1.84e-2)" "unprognostic (4.96e-2)" "unprognostic (1.44e-1)" "unprognostic (1.42e-2)" "potential prognostic favorable (9.79e-4)" "unprognostic (7.60e-3)" "unprognostic (2.41e-1)" "unprognostic (1.33e-2)" "unprognostic (3.49e-3)" ADI1 "APL1, ARD, FLJ10913, HMFT1638, MTCBP-1, mtnD, SIPL" ENSG00000182551 "Acireductone dioxygenase 1" Q9BV57 2 3497366-3519531 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Amino-acid biosynthesis, Methionine biosynthesis" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 552.4" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 308.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035403, HPA035404" Approved Supported "Nucleoplasm,Golgi apparatus" NA NA 96000 "Cluster 29: Non-specific - Unknown function" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 93: Hepatocytes - Bile production & excretion" 2 Nucleoplasm "Golgi apparatus" "HPA035403: , HPA035404: " "unprognostic (6.08e-2)" "unprognostic (1.47e-1)" "potential prognostic favorable (6.50e-5)" "unprognostic (1.08e-1)" "unprognostic (3.18e-2)" "unprognostic (7.51e-3)" "unprognostic (2.77e-3)" "unprognostic (2.66e-2)" "unprognostic (2.01e-1)" "unprognostic (2.80e-1)" "potential prognostic favorable (3.22e-7)" "unprognostic (1.68e-1)" "unprognostic (3.00e-2)" "unprognostic (1.62e-2)" "unprognostic (3.93e-3)" "unprognostic (1.13e-1)" "unprognostic (7.77e-3)" "unprognostic (2.39e-2)" "unprognostic (1.30e-1)" "unprognostic (1.88e-1)" "unprognostic (2.56e-1)" "unprognostic (3.18e-2)" "unprognostic (2.66e-1)" "unprognostic (5.85e-2)" "unprognostic (9.93e-2)" "unprognostic (7.51e-2)" "unprognostic (4.09e-3)" "unprognostic (2.21e-1)" "unprognostic (4.08e-2)" "unprognostic (1.62e-2)" "unprognostic (1.17e-1)" ADIG "MGC39724, RP5-1100H13.2, SMAF1" ENSG00000182035 Adipogenin Q0VDE8 20 38581195-38588463 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 8 "testis: 18.7" "Cell type enriched" "Detected in some" 4 "Late spermatids: 1119.6" "Cell type enhanced" "Detected in single" "ependymal cell: 1.9" "Cancer enhanced" "Detected in single" "Thyroid Carcinoma (TCGA): 1.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA041124 Uncertain NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 33: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" "HPA041124: " "unprognostic (4.85e-2)" ADIPOQ "ACDC, ACRP30, adiponectin, apM1, GBP28" ENSG00000181092 "Adiponectin, C1Q and collagen domain containing" Q15848 3 186842704-186858463 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" Hormone "Diabetes mellitus, Disease variant, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "adipose tissue: 843.2;breast: 252.6" "Cell type enriched" "Detected in some" 38 "Adipocytes: 482.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Breast Invasive Carcinoma (TCGA): 15.2;Pancreatic Adenocarcinoma (TCGA): 3.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Minor Salivary Gland - Adipocytes (Minor salivary gland), Skin - Adipocytes (Skin)" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB046467, HPA051767" Uncertain "Secreted to blood" Hormone NA NA 8360000000 890000000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 48: Non-specific - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 89: Adipocytes - Lipid metabolism" 46 "CAB046467: , HPA051767: " "unprognostic (5.31e-2)" "unprognostic (1.56e-2)" "potential prognostic favorable (6.80e-4)" "unprognostic (1.57e-1)" "unprognostic (7.54e-2)" "unprognostic (8.12e-3)" "unprognostic (1.59e-3)" "unprognostic (4.21e-2)" ADIPOR1 "ACDCR1, PAQR1" ENSG00000159346 "Adiponectin receptor 1" Q96A54 1 202940826-202958572 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythrocytes: 383.8;Esophageal apical cells: 895.3;Neutrophils: 304.8;Platelets: 617.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 36: Choroid plexus - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 84: Apical squamous epithelium - Cornification" 3 "unprognostic (4.45e-1)" "unprognostic (1.50e-1)" "unprognostic (6.49e-2)" "unprognostic (1.60e-2)" "unprognostic (2.99e-1)" "unprognostic (1.62e-2)" "unprognostic (1.38e-1)" "unprognostic (8.62e-3)" "unprognostic (3.12e-1)" "unprognostic (1.38e-3)" "potential prognostic favorable (1.83e-5)" "unprognostic (1.63e-1)" "unprognostic (3.22e-3)" "unprognostic (5.06e-2)" "unprognostic (1.92e-1)" "unprognostic (7.79e-2)" "unprognostic (7.09e-2)" "unprognostic (4.67e-2)" "unprognostic (1.41e-1)" "unprognostic (1.70e-1)" "unprognostic (1.36e-2)" "unprognostic (1.27e-2)" "unprognostic (1.49e-1)" "unprognostic (1.75e-1)" "unprognostic (3.31e-2)" "unprognostic (3.37e-3)" "unprognostic (2.43e-2)" "unprognostic (2.01e-3)" "unprognostic (1.60e-1)" "unprognostic (7.56e-2)" "unprognostic (2.94e-1)" ADIPOR2 "ACDCR2, PAQR2" ENSG00000006831 "Adiponectin receptor 2" Q86V24 12 1688574-1788674 "Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 121.3" "Cell type enhanced" "Detected in many" "Bergmann glia: 142.2;Choroid plexus epithelial cells: 101.4;Distal convoluted tubule cells: 79.0;Microglia: 121.7;Oligodendrocytes: 457.2;Renal collecting duct intercalated cells: 267.4;Renal connecting tubule cells: 89.2" "Group enriched" "Detected in all" 4 "endothelial cell: 912.8;oligodendrocyte: 643.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Minor Salivary Gland - Minor salivary gland basal cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043737 Approved NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 38: Non-specific - Transcription" "Cluster 104: Brain endothelial cells - Blood brain barrier" 5 "HPA043737: " "unprognostic (2.71e-2)" "unprognostic (6.87e-2)" "unprognostic (1.20e-1)" "unprognostic (3.32e-2)" "unprognostic (8.81e-2)" "unprognostic (1.87e-2)" "unprognostic (2.12e-1)" "unprognostic (1.27e-1)" "unprognostic (8.78e-2)" "potential prognostic unfavorable (7.05e-4)" "potential prognostic favorable (5.97e-5)" "unprognostic (2.97e-2)" "unprognostic (1.24e-1)" "unprognostic (1.60e-1)" "unprognostic (1.11e-1)" "potential prognostic unfavorable (4.49e-4)" "unprognostic (2.35e-1)" "unprognostic (1.34e-1)" "unprognostic (1.61e-1)" "unprognostic (2.53e-2)" "unprognostic (2.90e-1)" "unprognostic (1.40e-2)" "unprognostic (5.97e-3)" "unprognostic (1.08e-1)" "unprognostic (1.16e-2)" "unprognostic (9.23e-2)" "unprognostic (2.49e-2)" "unprognostic (3.12e-1)" "unprognostic (1.07e-1)" "unprognostic (3.07e-2)" "unprognostic (2.34e-1)" ADIRF "AFRO, APM2, C10orf116" ENSG00000148671 "Adipogenesis regulatory factor" Q15847 10 86968432-86983934 "Plasma proteins, Predicted intracellular proteins" "Differentiation, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 1337.8;blood vessel: 2350.8" "Cell type enhanced" "Detected in many" "Enterocytes: 10459.6;Epididymal efferent duct absorptive cells: 2189.3;Esophageal apical cells: 7376.6;Ocular epithelial cells: 4551.1;Urothelial cells: 3177.2;Vascular smooth muscle cells: 5029.0" "Cell type enhanced" "Detected in many" "endothelial cell: 157.3;pericyte: 231.9;vascular associated smooth muscle cell: 739.6" "Cancer enhanced" "Detected in all" "Bladder Urothelial Carcinoma (TCGA): 1604.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 2.6;naive CD8 T-cell: 1.9" "Lineage enriched" "Detected in single" 8 "T-cells: 2.6" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 835.4" "Low region specificity" "Detected in all" HPA026810 Approved Supported Nucleoplasm,Cytosol NA NA 360000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 103: Non-specific - Basic cellular processes" 1 "Nucleoplasm, Cytosol" "HPA026810: " "unprognostic (5.78e-3)" "unprognostic (2.67e-1)" "unprognostic (1.69e-2)" "unprognostic (8.03e-2)" "unprognostic (1.83e-1)" "unprognostic (1.30e-1)" "unprognostic (2.85e-1)" "unprognostic (4.00e-1)" "unprognostic (3.09e-3)" "validated prognostic favorable (3.11e-5)" "validated prognostic favorable (3.10e-5)" "potential prognostic favorable (5.87e-4)" "unprognostic (5.14e-3)" "unprognostic (1.88e-2)" "unprognostic (5.66e-2)" "unprognostic (1.41e-1)" "unprognostic (8.64e-2)" "unprognostic (5.46e-3)" "unprognostic (9.65e-2)" "unprognostic (1.74e-3)" "unprognostic (1.80e-3)" "unprognostic (3.00e-2)" "unprognostic (3.31e-1)" "unprognostic (4.56e-2)" "unprognostic (3.89e-1)" "unprognostic (5.58e-2)" "unprognostic (8.03e-2)" "unprognostic (1.16e-1)" "unprognostic (5.65e-2)" ADK AK ENSG00000156110 "Adenosine kinase" P55263 10 74151202-74709963 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Purine salvage" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 141.2" "Cell type enhanced" "Detected in all" "Sertoli cells: 1311.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Lung - Alveolar cells type 2, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032876, HPA038391, HPA038409, HPA075222" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 510000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 14: Neurons - Synaptic function" "Cluster 52: Non-specific - Mitochondria" "Cluster 87: B-cells - Adaptive immunity: Humoral response" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB032876: , HPA038391: , HPA038409: , HPA075222: " "unprognostic (2.53e-1)" "validated prognostic unfavorable (8.76e-5)" "validated prognostic unfavorable (4.44e-5)" "unprognostic (2.54e-1)" "unprognostic (1.58e-1)" "unprognostic (3.95e-2)" "unprognostic (6.25e-3)" "potential prognostic favorable (5.63e-5)" "potential prognostic unfavorable (9.09e-5)" "unprognostic (1.21e-1)" "potential prognostic favorable (5.93e-6)" "unprognostic (6.80e-2)" "unprognostic (1.46e-1)" "unprognostic (1.11e-3)" "unprognostic (2.50e-2)" "unprognostic (8.38e-2)" "unprognostic (6.47e-2)" "unprognostic (1.02e-1)" "unprognostic (5.95e-2)" "unprognostic (3.33e-1)" "unprognostic (9.44e-2)" "unprognostic (3.62e-3)" "unprognostic (4.00e-3)" "unprognostic (5.60e-2)" "unprognostic (1.30e-2)" "unprognostic (1.80e-1)" "unprognostic (1.48e-1)" "unprognostic (3.79e-1)" "unprognostic (5.19e-2)" "unprognostic (2.58e-2)" "unprognostic (8.55e-2)" ADM AM ENSG00000148926 Adrenomedullin P35318 11 10305073-10307397 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Hormone "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 339.7" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 1276.5;Extravillous trophoblasts: 1814.1;Migrating cytotrophoblasts: 407.1;Neutrophils: 524.3;Syncytiotrophoblasts: 1452.7" "Group enriched" "Detected in many" 4 "astrocyte: 96.0;fibroblast: 25.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 18 "neutrophil: 243.4" "Lineage enriched" "Detected in many" 18 "granulocytes: 243.4" "Low cancer specificity" "Detected in all" "Liver - Neutrophils, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB016075, HPA068955" Approved "Secreted to blood" Hormone NA NA 31000 440000 "Cluster 4: Neutrophils - Degranulation" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 19: Astrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." "CAB016075: , HPA068955: " "unprognostic (1.55e-2)" "unprognostic (1.33e-1)" "unprognostic (1.68e-1)" "unprognostic (5.19e-3)" "unprognostic (2.92e-1)" "unprognostic (2.58e-1)" "unprognostic (1.93e-3)" "unprognostic (3.60e-3)" "unprognostic (6.84e-3)" "unprognostic (1.37e-3)" "unprognostic (3.37e-3)" "unprognostic (3.90e-2)" "unprognostic (1.14e-2)" "potential prognostic unfavorable (2.32e-4)" "unprognostic (1.32e-3)" "validated prognostic unfavorable (1.97e-5)" "validated prognostic unfavorable (4.08e-4)" "unprognostic (1.28e-1)" "unprognostic (2.80e-2)" "unprognostic (7.03e-2)" "unprognostic (1.76e-1)" "unprognostic (1.00e-2)" "potential prognostic unfavorable (2.15e-4)" "unprognostic (1.28e-1)" "unprognostic (5.49e-2)" "unprognostic (1.74e-1)" "unprognostic (3.92e-1)" "unprognostic (7.27e-3)" "unprognostic (2.19e-1)" "unprognostic (1.36e-1)" "unprognostic (2.16e-1)" ADM2 "AM2, FLJ21135" ENSG00000128165 "Adrenomedullin 2" Q7Z4H4 22 50481543-50486440 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 7.7;pancreas: 14.6;thyroid gland: 10.8" "Cell type enhanced" "Detected in some" "Breast lactating cells: 5.3;Enterocytes: 7.8;Epididymal basal cells: 5.1;Epididymal efferent duct absorptive cells: 19.9;Epididymal principal cells: 9.3;Esophageal apical cells: 5.8;Foveolar cells: 7.4;Gastric chief cells: 12.0;Gastric progenitor cells: 7.7;Goblet cells: 7.7;Pancreatic acinar cells: 9.6;Plasma cells: 8.2;Proximal tubule cells: 8.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Myeloma: 22.0" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" Hormone NA NA 61300 "Cluster 8: Pancreas - Proteolysis" "Cluster 15: Non-specific - Transcription" "Cluster 13: Non-specific - Mixed function" "Cluster 78: Plasma cells - Antibody production & ER-stress response" "unprognostic (1.51e-1)" "unprognostic (1.33e-2)" "unprognostic (1.08e-1)" "unprognostic (1.38e-1)" "unprognostic (4.01e-2)" "unprognostic (8.73e-2)" "unprognostic (3.91e-1)" "unprognostic (1.73e-1)" "potential prognostic favorable (3.42e-4)" "unprognostic (3.86e-2)" "unprognostic (4.65e-3)" "unprognostic (1.66e-2)" "unprognostic (4.23e-1)" "unprognostic (1.85e-2)" "unprognostic (1.22e-1)" "unprognostic (2.53e-1)" "unprognostic (3.69e-2)" "unprognostic (2.07e-1)" "unprognostic (1.56e-1)" "unprognostic (8.37e-2)" "unprognostic (1.23e-1)" "unprognostic (4.68e-2)" "unprognostic (1.70e-1)" "unprognostic (4.69e-3)" "unprognostic (4.12e-1)" "unprognostic (3.55e-2)" "unprognostic (1.04e-1)" "potential prognostic unfavorable (1.49e-4)" "unprognostic (3.04e-1)" ADM5 "AM5, C19orf76" ENSG00000224420 "Adrenomedullin 5 (putative)" C9JUS6 19 49689594-49690575 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast secretory cells: 8.4;Early spermatids: 10.7;Endometrial luminal cells: 6.7;Endometrial secretory cells: 10.7;Esophageal apical cells: 16.5;Hepatic stellate cells: 6.5;Late spermatids: 7.3;Vascular endothelial cells: 39.3" "Cell type enriched" "Detected in some" 5 "endothelial cell: 10.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Endothelial cells, Minor Salivary Gland - Endothelial cells" "Secreted to blood" "No annotated function" NA NA "Cluster 5: Spleen - Immune response" "Cluster 15: Non-specific - Transcription" "Cluster 35: RS4;11 - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "unprognostic (1.09e-1)" "unprognostic (5.24e-2)" "unprognostic (2.41e-1)" "unprognostic (4.44e-3)" "unprognostic (2.20e-1)" "unprognostic (2.46e-1)" "unprognostic (1.57e-2)" "unprognostic (1.11e-1)" "unprognostic (4.23e-3)" "unprognostic (1.89e-1)" "unprognostic (1.21e-1)" "unprognostic (1.79e-2)" "unprognostic (1.77e-2)" "unprognostic (3.81e-2)" "unprognostic (2.99e-3)" "unprognostic (8.60e-2)" "unprognostic (2.71e-2)" "unprognostic (2.47e-2)" "unprognostic (7.45e-2)" ADNP "ADNP1, KIAA0784" ENSG00000101126 "Activity dependent neuroprotector homeobox" Q9H2P0 20 50888916-50931437 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Autism spectrum disorder, Cancer-related genes, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006371, HPA050560" Supported Approved "Nucleoplasm,Primary cilium,Primary cilium tip,Centrosome,Basal body" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 39: Testis - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 7: Non-specific - Transcription" 42 "Nucleoplasm, Centrosome" "Primary cilium, Primary cilium tip, Basal body" "HPA006371: , HPA050560: " "unprognostic (4.39e-2)" "unprognostic (1.02e-2)" "unprognostic (3.69e-1)" "unprognostic (1.46e-1)" "unprognostic (6.66e-2)" "unprognostic (8.20e-2)" "unprognostic (2.09e-1)" "unprognostic (6.61e-2)" "unprognostic (5.74e-2)" "unprognostic (1.33e-2)" "unprognostic (4.06e-3)" "unprognostic (3.19e-2)" "unprognostic (2.86e-1)" "potential prognostic unfavorable (6.69e-5)" "unprognostic (1.38e-2)" "unprognostic (4.36e-1)" "unprognostic (2.92e-2)" "unprognostic (1.27e-1)" "unprognostic (2.62e-2)" "unprognostic (2.06e-2)" "unprognostic (1.92e-2)" "unprognostic (7.35e-2)" "unprognostic (1.73e-2)" "unprognostic (2.88e-2)" "unprognostic (7.76e-3)" "unprognostic (1.32e-2)" "unprognostic (7.29e-2)" "unprognostic (2.67e-1)" "unprognostic (3.46e-1)" "unprognostic (1.23e-2)" "unprognostic (3.45e-1)" ADNP2 "KIAA0863, ZNF508" ENSG00000101544 "ADNP homeobox 2" Q6IQ32 18 80109262-80147523 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 39.0" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007126 Uncertain Approved Mitochondria,Cytosol NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 12 "Mitochondria, Cytosol" "HPA007126: " "unprognostic (3.46e-2)" "unprognostic (5.99e-2)" "unprognostic (1.34e-1)" "unprognostic (2.52e-3)" "unprognostic (1.32e-1)" "unprognostic (3.03e-1)" "unprognostic (1.95e-1)" "unprognostic (3.97e-2)" "unprognostic (2.32e-1)" "unprognostic (7.79e-2)" "potential prognostic favorable (2.64e-4)" "unprognostic (3.81e-3)" "unprognostic (2.65e-1)" "unprognostic (1.11e-1)" "unprognostic (1.19e-2)" "unprognostic (2.10e-2)" "unprognostic (1.58e-2)" "unprognostic (2.16e-1)" "unprognostic (2.23e-2)" "unprognostic (5.20e-2)" "unprognostic (1.39e-1)" "unprognostic (9.71e-2)" "unprognostic (1.02e-1)" "unprognostic (1.00e-1)" "unprognostic (2.57e-2)" "unprognostic (2.59e-2)" "unprognostic (1.59e-1)" "unprognostic (2.61e-1)" "unprognostic (5.34e-1)" "unprognostic (3.56e-3)" "unprognostic (1.62e-2)" ADO "C10orf22, FLJ14547" ENSG00000181915 "2-aminoethanethiol dioxygenase" Q96SZ5 10 62804720-62808479 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 10 "Early spermatids: 161.2;Late primary spermatocytes: 248.5;Late spermatids: 524.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039194, HPA040437" Approved NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 2 "HPA039194: , HPA040437: " "unprognostic (2.44e-2)" "unprognostic (2.50e-2)" "unprognostic (1.30e-1)" "unprognostic (1.56e-2)" "unprognostic (1.87e-1)" "potential prognostic unfavorable (8.19e-6)" "unprognostic (2.63e-2)" "potential prognostic favorable (7.41e-6)" "unprognostic (2.19e-1)" "unprognostic (1.20e-2)" "potential prognostic favorable (3.67e-5)" "unprognostic (1.11e-1)" "unprognostic (8.29e-2)" "potential prognostic unfavorable (6.82e-4)" "unprognostic (1.45e-1)" "unprognostic (4.75e-2)" "unprognostic (1.02e-1)" "unprognostic (1.58e-1)" "unprognostic (2.36e-2)" "unprognostic (4.96e-2)" "unprognostic (1.32e-2)" "unprognostic (1.92e-2)" "unprognostic (1.44e-2)" "unprognostic (5.80e-3)" "unprognostic (6.02e-2)" "unprognostic (1.68e-2)" "unprognostic (3.44e-1)" "unprognostic (5.01e-2)" "unprognostic (1.76e-1)" "unprognostic (1.12e-1)" "unprognostic (1.10e-1)" ADORA1 RDC7 ENSG00000163485 "Adenosine A1 receptor" P30542 1 203090654-203167405 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 42.6;testis: 20.2" "Cell type enhanced" "Detected in many" "Adipocytes: 20.5;Astrocytes: 30.3;Brain excitatory neurons: 21.9;Breast secretory cells: 19.9;Müller glia: 60.9;Oligodendrocyte progenitor cells: 54.5;Oligodendrocytes: 55.1;Pancreatic duct cells: 30.8;Podocytes: 138.9;Retinal amacrine cells: 19.7;Sertoli cells: 28.8" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 66.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 51.9" "Adipose subcutaneous - Adipocytes (Subcutaneous), Heart muscle - Cardiomyocytes, Kidney - Podocytes, Prostate - Fibroblasts, Skin - Eccrine sweat gland cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044383, CAB080543" Approved Supported "Plasma membrane,Primary cilium" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 49: Hindbrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 57: Podocytes - Glomerular filtration" 9 "Plasma membrane" "Primary cilium" "CAB080543: , HPA044383: " "unprognostic (1.90e-2)" "unprognostic (7.77e-3)" "unprognostic (6.77e-2)" "unprognostic (6.62e-2)" "unprognostic (1.57e-1)" "unprognostic (6.55e-2)" "unprognostic (5.86e-2)" "unprognostic (1.60e-3)" "unprognostic (2.40e-1)" "unprognostic (1.03e-1)" "unprognostic (5.16e-3)" "unprognostic (8.88e-2)" "potential prognostic unfavorable (4.46e-4)" "unprognostic (3.10e-2)" "unprognostic (2.84e-1)" "unprognostic (5.65e-3)" "unprognostic (1.94e-3)" "potential prognostic unfavorable (8.41e-4)" "unprognostic (8.47e-2)" "unprognostic (1.06e-3)" "unprognostic (5.04e-2)" "unprognostic (3.75e-2)" "unprognostic (9.22e-2)" "unprognostic (1.41e-1)" "unprognostic (1.31e-1)" "unprognostic (1.20e-1)" "unprognostic (3.51e-2)" "unprognostic (9.36e-2)" "unprognostic (2.44e-2)" "unprognostic (2.23e-2)" ADORA2A "ADORA2, RDC8" ENSG00000128271 "Adenosine A2a receptor" P29274 22 24417879-24442357 "Cancer-related genes, FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 38.3;brain: 108.6;lymphoid tissue: 50.4" "Group enriched" "Detected in some" 4 "Brain inhibitory neurons: 15.4;Pericytes: 3.9" "Cell type enhanced" "Detected in many" "medium spiny neuron: 46.3;pericyte: 95.5" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 8 "basal ganglia: 200.5" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "lymphoma: 45.6;Myeloma: 39.1" "Region enriched" "Detected in many" 9 "basal ganglia: 399.9" "Region enriched" "Detected in many" 50 "basal ganglia: 187.1" "CAB001943, HPA065566, HPA075997" Enhanced Supported Approved "Vesicles,Plasma membrane,Primary cilium" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 35: Neurons - Synaptic function & neurogenesis" 16 "Plasma membrane" "Vesicles, Primary cilium" "CAB001943: , HPA065566: , HPA075997: " "unprognostic (6.30e-2)" "unprognostic (9.31e-2)" "unprognostic (1.67e-1)" "unprognostic (8.72e-3)" "unprognostic (1.52e-1)" "unprognostic (8.94e-2)" "unprognostic (1.67e-1)" "potential prognostic favorable (3.96e-4)" "unprognostic (5.64e-3)" "potential prognostic favorable (8.35e-4)" "unprognostic (3.52e-2)" "unprognostic (1.19e-2)" "unprognostic (3.04e-1)" "unprognostic (1.18e-2)" "unprognostic (1.03e-2)" "unprognostic (7.58e-2)" "unprognostic (2.24e-3)" "unprognostic (9.51e-2)" "unprognostic (2.79e-2)" "unprognostic (3.59e-2)" "potential prognostic favorable (2.01e-4)" "unprognostic (1.40e-1)" "unprognostic (1.27e-1)" "unprognostic (3.46e-1)" "unprognostic (5.33e-2)" "unprognostic (1.19e-1)" "unprognostic (1.68e-1)" "unprognostic (4.73e-2)" "unprognostic (4.08e-1)" "unprognostic (3.40e-1)" ADORA2B ENSG00000170425 "Adenosine A2b receptor" P29275 17 15945130-15975746 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.5;urinary bladder: 15.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 81.9;Bergmann glia: 41.6;Conjunctival goblet cells: 45.6;Esophageal basal cells: 47.4;Respiratory basal cells: 30.1;Respiratory secretory cells: 34.5;Retinal pigment epithelial cells: 59.7;Suprabasal keratinocytes: 57.3;Urothelial cells: 33.5" "Cell type enhanced" "Detected in many" "Bergmann glia: 42.2;pericyte: 75.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 17.3;myeloid DC: 10.5" "Group enriched" "Detected in many" 113 "dendritic cells: 10.5;granulocytes: 17.3;monocytes: 5.9" "Low cancer specificity" "Detected in many" "Breast - Breast myoepithelial cells, Prostate - Urothelial cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073747 Supported "Vesicles,Plasma membrane,Primary cilium tip" NA Yes "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 49: HMC-1 - Innate immune response" "Cluster 26: Keratinocytes - Keratinization" 28 "Plasma membrane" "Vesicles, Primary cilium tip" "HPA073747: " "unprognostic (7.71e-2)" "unprognostic (7.31e-2)" "unprognostic (1.90e-2)" "unprognostic (1.93e-2)" "unprognostic (1.24e-1)" "unprognostic (1.65e-2)" "unprognostic (2.97e-2)" "unprognostic (1.31e-1)" "unprognostic (9.21e-3)" "potential prognostic unfavorable (3.29e-11)" "unprognostic (1.43e-2)" "unprognostic (5.82e-2)" "unprognostic (1.14e-1)" "unprognostic (8.63e-3)" "unprognostic (6.40e-2)" "unprognostic (9.42e-2)" "unprognostic (1.31e-3)" "unprognostic (1.98e-2)" "unprognostic (1.83e-1)" "unprognostic (5.14e-1)" "unprognostic (2.00e-1)" "unprognostic (8.92e-2)" "unprognostic (3.43e-1)" "unprognostic (4.79e-2)" ADORA3 "A3AR, AD026" ENSG00000282608 "Adenosine A3 receptor" P0DMS8 1 111499429-111503633 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.8" "Group enriched" "Detected in some" 6 "Early spermatids: 2.9;Late spermatids: 4.7;Mast cells: 1.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 37.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 40 "eosinophil: 602.8" "Lineage enriched" "Detected in many" 40 "granulocytes: 602.8" "Cancer enriched" "Detected in single" 6 "Leukemia: 1.9" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in many" NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" "unprognostic (6.22e-3)" "unprognostic (1.21e-3)" "unprognostic (1.64e-1)" "unprognostic (5.95e-2)" "unprognostic (2.49e-2)" "unprognostic (9.09e-3)" "unprognostic (7.27e-2)" "unprognostic (2.59e-1)" "unprognostic (1.43e-1)" "unprognostic (8.78e-3)" "unprognostic (2.30e-1)" "potential prognostic favorable (2.48e-4)" "unprognostic (7.41e-3)" "unprognostic (2.24e-1)" "unprognostic (6.85e-3)" "unprognostic (2.27e-3)" "unprognostic (3.93e-2)" "unprognostic (2.38e-2)" "unprognostic (5.51e-3)" "unprognostic (7.31e-2)" "unprognostic (3.36e-2)" "unprognostic (5.37e-2)" "unprognostic (1.92e-1)" "unprognostic (1.00e-1)" "unprognostic (1.44e-3)" "unprognostic (1.31e-2)" "potential prognostic favorable (1.67e-5)" "unprognostic (6.36e-3)" ADPGK "ADP-GK, DKFZp434B195" ENSG00000159322 "ADP dependent glucokinase" Q9BRR6 15 72751294-72785846 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Glycolysis "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Kupffer cells: 166.0;Neutrophil progenitors: 164.0;Neutrophils: 172.2" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 165.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045194, HPA058525" Approved Approved Centrosome "Intracellular and membrane" Enzyme NA NA 56000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 44: Non-specific - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 2 Centrosome "HPA045194: , HPA058525: " "unprognostic (4.98e-3)" "unprognostic (3.15e-1)" "unprognostic (2.97e-2)" "unprognostic (4.42e-3)" "unprognostic (1.01e-1)" "unprognostic (3.76e-2)" "unprognostic (3.51e-1)" "unprognostic (7.85e-2)" "unprognostic (1.73e-1)" "unprognostic (8.64e-3)" "potential prognostic favorable (2.14e-5)" "unprognostic (3.04e-1)" "unprognostic (1.01e-2)" "unprognostic (2.89e-1)" "unprognostic (8.45e-2)" "unprognostic (1.83e-1)" "unprognostic (5.43e-2)" "unprognostic (1.16e-1)" "unprognostic (1.96e-2)" "unprognostic (1.06e-1)" "unprognostic (2.41e-2)" "unprognostic (2.09e-2)" "unprognostic (4.81e-3)" "unprognostic (1.23e-1)" "unprognostic (1.49e-2)" "unprognostic (1.34e-2)" "unprognostic (1.87e-1)" "unprognostic (1.91e-1)" "unprognostic (5.19e-1)" "unprognostic (8.77e-2)" "unprognostic (2.80e-2)" ADPRH ARH1 ENSG00000144843 "ADP-ribosylarginine hydrolase" P54922 3 119579268-119589945 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 14.1;Cardiomyocytes: 14.1;cDC: 21.7;Kupffer cells: 18.4;Macrophages: 18.3;Mast cells: 20.0;Megakaryocytes: 37.1;monocytes: 14.8;Syncytiotrophoblasts: 19.1;Thymic myoid cells: 19.0" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 9.7;choroid plexus epithelial cell: 7.2;endothelial cell: 9.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "lymphoma: 14.3" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001701, HPA036961" Approved Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 58: Mast cells - Allergic inflammatory responses" 2 "Nuclear membrane" Nucleoplasm "CAB001701: , HPA036961: " "unprognostic (3.15e-1)" "unprognostic (5.36e-2)" "unprognostic (2.05e-1)" "unprognostic (3.29e-1)" "unprognostic (3.76e-2)" "unprognostic (1.31e-2)" "unprognostic (5.57e-2)" "potential prognostic unfavorable (6.13e-5)" "unprognostic (2.47e-1)" "unprognostic (2.64e-2)" "potential prognostic favorable (4.44e-9)" "unprognostic (2.17e-2)" "unprognostic (2.63e-3)" "unprognostic (3.27e-2)" "unprognostic (3.46e-1)" "unprognostic (1.32e-1)" "unprognostic (4.85e-2)" "unprognostic (1.37e-2)" "unprognostic (3.47e-3)" "unprognostic (1.10e-2)" "unprognostic (1.22e-2)" "unprognostic (1.95e-1)" "unprognostic (2.40e-1)" "unprognostic (3.47e-2)" "unprognostic (1.72e-2)" "unprognostic (3.29e-3)" "unprognostic (2.81e-2)" "unprognostic (3.23e-3)" "unprognostic (2.32e-1)" "unprognostic (5.59e-2)" "unprognostic (6.07e-3)" ADPRHL1 ARH2 ENSG00000153531 "ADP-ribosylhydrolase like 1" Q8NDY3 13 113399611-113453488 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 32 "heart muscle: 274.1;skeletal muscle: 246.1;tongue: 213.8" "Group enriched" "Detected in many" 8 "Cardiomyocytes: 186.5;Myonuclei: 150.6;Thymic myoid cells: 403.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Pituitary gland - Gonadotropes, Prostate - Smooth muscle cells, Testis - Spermatogonia" "Region enhanced" "Detected in single" "cerebellum: 2.3" "Low region specificity" "Detected in some" "HPA043951, HPA066478, HPA072123" Enhanced Approved "Nucleoli,Plasma membrane" NA NA "Cluster 41: Striated muscle - Muscle contraction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 46: Skeletal myocytes - Muscle structure & formation" "Plasma membrane" Nucleoli "HPA043951: , HPA066478: , HPA072123: " "unprognostic (1.60e-2)" "unprognostic (1.19e-1)" "unprognostic (4.71e-2)" "unprognostic (7.84e-2)" "unprognostic (2.30e-1)" "unprognostic (1.72e-1)" "unprognostic (2.43e-1)" "unprognostic (3.58e-2)" "potential prognostic unfavorable (7.75e-4)" "unprognostic (9.87e-3)" "unprognostic (2.74e-3)" "potential prognostic unfavorable (1.19e-5)" "unprognostic (1.13e-2)" "potential prognostic unfavorable (4.05e-5)" "unprognostic (3.41e-1)" "unprognostic (6.41e-2)" "unprognostic (2.04e-1)" "unprognostic (3.95e-1)" "unprognostic (1.09e-1)" "unprognostic (2.17e-2)" "unprognostic (6.22e-1)" "unprognostic (1.23e-1)" "unprognostic (1.22e-1)" "unprognostic (7.66e-2)" "unprognostic (8.60e-2)" "unprognostic (2.10e-1)" "unprognostic (9.34e-3)" "unprognostic (8.06e-2)" ADPRM "C17orf48, MDS006" ENSG00000170222 "ADP-ribose/CDP-alcohol diphosphatase, manganese dependent" Q3LIE5 17 10697594-10711558 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 55.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023265, HPA023820, HPA069342" Approved Approved Nucleoplasm NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 42: Non-specific - Unknown function" "Cluster 9: T-cells - Adaptive immunity: Regulation" Nucleoplasm "HPA023265: , HPA023820: , HPA069342: " "unprognostic (2.35e-1)" "unprognostic (4.01e-3)" "unprognostic (7.72e-3)" "unprognostic (3.84e-1)" "unprognostic (1.08e-1)" "unprognostic (1.25e-2)" "unprognostic (4.29e-2)" "unprognostic (1.60e-2)" "unprognostic (1.82e-1)" "potential prognostic favorable (3.32e-6)" "unprognostic (2.61e-3)" "unprognostic (5.82e-2)" "unprognostic (2.10e-1)" "unprognostic (3.03e-2)" "unprognostic (4.19e-2)" "unprognostic (8.24e-2)" "unprognostic (2.77e-1)" "unprognostic (2.73e-1)" "unprognostic (1.41e-2)" "unprognostic (2.74e-2)" "unprognostic (7.83e-2)" "unprognostic (4.64e-1)" "unprognostic (2.71e-2)" "unprognostic (7.99e-2)" "unprognostic (6.74e-2)" "unprognostic (2.77e-2)" "unprognostic (9.18e-2)" "unprognostic (1.68e-2)" "unprognostic (2.33e-1)" ADPRS "ADPRHL2, ARH3, FLJ20446" ENSG00000116863 "ADP-ribosylserine hydrolase" Q9NX46 1 36088892-36093932 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" Hydrolase "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 99.6;Esophageal apical cells: 132.1;Esophageal suprabasal cells: 119.8" "Cell type enhanced" "Detected in all" "ependymal cell: 55.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026641, HPA027104, HPA027141" Approved Enhanced Nucleoplasm NA NA 78000 "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 37: Non-specific - mRNA processing" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 1 Nucleoplasm "HPA026641: , HPA027104: , HPA027141: " "unprognostic (1.63e-2)" "unprognostic (9.70e-3)" "unprognostic (4.13e-2)" "unprognostic (5.68e-2)" "unprognostic (4.94e-2)" "unprognostic (4.11e-2)" "unprognostic (7.56e-3)" "unprognostic (9.73e-2)" "unprognostic (3.14e-2)" "unprognostic (3.48e-2)" "unprognostic (2.58e-1)" "unprognostic (4.22e-2)" "potential prognostic unfavorable (9.01e-9)" "unprognostic (1.14e-1)" "unprognostic (7.42e-2)" "unprognostic (2.64e-1)" "unprognostic (6.26e-2)" "unprognostic (2.37e-1)" "unprognostic (5.87e-2)" "unprognostic (5.68e-2)" "unprognostic (7.08e-2)" "unprognostic (2.70e-1)" "unprognostic (1.67e-1)" "unprognostic (1.06e-1)" "unprognostic (8.57e-2)" "unprognostic (5.96e-2)" "unprognostic (2.23e-2)" "unprognostic (3.77e-1)" "unprognostic (1.74e-1)" ADRA1A "ADRA1C, ADRA1L1" ENSG00000120907 "Adrenoceptor alpha 1A" P35348 8 26748150-26867278 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 20.5;liver: 56.2" "Cell type enhanced" "Detected in some" "Adipocytes: 234.0;Astrocytes: 187.4;Bergmann glia: 432.3;Brain excitatory neurons: 102.4;Cardiomyocytes: 204.8;Early spermatids: 131.7;Hepatocytes: 603.7;Medullary thymic epithelial cells: 91.2;Oligodendrocyte progenitor cells: 192.1;Other brain neurons: 85.6;Pituicytes/FSCs: 108.4;Smooth muscle cells: 205.3;Vascular smooth muscle cells: 93.7" "Cell type enhanced" "Detected in many" "Bergmann glia: 455.0;hippocampal dentate gyrus: 910.2" "Cancer enhanced" "Detected in some" "Liver Hepatocellular Carcinoma (TCGA): 2.9;Prostate Adenocarcinoma (TCGA): 2.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "Bone cancer: 4.1" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Skin - Smooth muscle cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA029678, HPA029679, HPA076693" Approved Supported Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 29: Forebrain - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" 4 Cytosol "Nucleoplasm, Vesicles" "HPA029678: , HPA029679: , HPA076693: " "unprognostic (1.16e-1)" "unprognostic (1.79e-1)" "unprognostic (1.31e-3)" "potential prognostic favorable (1.35e-4)" "unprognostic (3.35e-2)" "unprognostic (4.83e-2)" ADRA1B ENSG00000170214 "Adrenoceptor alpha 1B" P35368 5 159865080-159973012 "Cancer-related genes, FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 17.2;liver: 11.4;lymphoid tissue: 10.6" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 25.0;Brain inhibitory neurons: 23.8;Epicardial cells: 27.3;Fibro-adipogenic progenitors: 51.2;Hepatic stellate cells: 116.2;Hepatocytes: 60.7;Mesothelial cells: 37.7;Other brain neurons: 30.5;Proximal tubule cells: 73.8;Retinal bipolar cells: 22.3;Transitional alveolar cells: 27.7" "Cell type enhanced" "Detected in many" "CGE interneuron: 144.7;hippocampal dentate gyrus: 115.4" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 7.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Breast - Adipocytes (Breast), Skin - Fibroblasts_2, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA074416 Supported "Plasma membrane" NA NA "Cluster 5: Spleen - Immune response" "Cluster 14: Neurons - Synaptic function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 35: Neurons - Synaptic function & neurogenesis" 3 "Plasma membrane" "HPA074416: " "unprognostic (1.98e-1)" "unprognostic (2.28e-3)" "unprognostic (2.30e-1)" "unprognostic (1.79e-2)" "unprognostic (3.25e-3)" "unprognostic (1.17e-2)" "unprognostic (9.60e-3)" "unprognostic (1.26e-3)" "unprognostic (5.80e-3)" "unprognostic (5.16e-2)" "unprognostic (7.14e-3)" "unprognostic (1.11e-1)" "unprognostic (1.88e-1)" "unprognostic (6.17e-3)" "unprognostic (9.64e-3)" "potential prognostic favorable (7.74e-4)" "potential prognostic unfavorable (7.17e-4)" ADRA1D "ADRA1, ADRA1A, ADRA1R" ENSG00000171873 "Adrenoceptor alpha 1D" P25100 20 4220630-4249287 "FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 6.6;brain: 6.1;cervix: 5.8" "Cell type enriched" "Detected in some" 4 "Epicardial cells: 47.8" "Group enriched" "Detected in many" 4 "CGE interneuron: 14.8;deep-layer near-projecting: 6.0;hippocampal CA1-3: 12.2;hippocampal CA4: 8.7;LAMP5-LHX6 and Chandelier: 15.6;mammillary body: 9.3;MGE interneuron: 5.0;splatter: 6.0;thalamic excitatory: 10.6;vascular associated smooth muscle cell: 3.9" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 2.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Bone cancer: 27.8" "Adipose visceral - Smooth muscle cells, Kidney - Fibroblasts, Minor Salivary Gland - Endothelial cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA038789 Uncertain NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 110: Mural cells - ECM organization" 13 "HPA038789: " "unprognostic (6.41e-2)" "unprognostic (4.95e-2)" "unprognostic (4.86e-2)" "unprognostic (2.05e-3)" ADRA2A "ADRA2, ADRA2R, ADRAR" ENSG00000150594 "Adrenoceptor alpha 2A" P08913 10 111077029-111080907 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 46.9" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 29.1;Cholangiocytes: 42.0;Endometrial glandular cells: 37.9;Epididymal efferent duct absorptive cells: 24.1;Megakaryocyte progenitors: 23.8;Pancreatic duct cells: 75.3;Pericytes: 51.1;Platelets: 118.5;Vascular smooth muscle cells: 156.9" "Cell type enhanced" "Detected in many" "vascular associated smooth muscle cell: 15.1" "Cancer enhanced" "Detected in many" "Pancreatic Adenocarcinoma (TCGA): 23.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 11.9" "Adipose visceral - Adipocytes (Visceral), Kidney - Fibroblasts, Minor Salivary Gland - Endothelial cells, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 103: Non-specific - Basic cellular processes" 2 "unprognostic (2.37e-3)" "unprognostic (2.18e-1)" "unprognostic (6.18e-2)" "unprognostic (2.75e-2)" "unprognostic (1.57e-1)" "unprognostic (1.33e-1)" "unprognostic (2.82e-2)" "unprognostic (2.54e-3)" "unprognostic (9.50e-2)" "unprognostic (7.08e-3)" "unprognostic (3.36e-3)" "unprognostic (1.83e-2)" "unprognostic (3.43e-2)" "unprognostic (2.16e-2)" "unprognostic (2.54e-3)" "potential prognostic favorable (2.96e-4)" "unprognostic (2.13e-1)" "unprognostic (1.28e-1)" "unprognostic (6.14e-3)" "unprognostic (2.52e-1)" "unprognostic (4.78e-2)" "potential prognostic favorable (2.03e-4)" "unprognostic (3.11e-2)" "unprognostic (5.96e-3)" "unprognostic (1.14e-1)" "unprognostic (8.70e-2)" "unprognostic (2.13e-1)" "unprognostic (6.17e-2)" "unprognostic (3.15e-3)" "unprognostic (1.87e-1)" ADRA2B "ADRA2L1, ADRA2RL1, ADRARL1" ENSG00000274286 "Adrenoceptor alpha 2B" P18089 2 96112876-96116571 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "cDC: 5.5;Endometrial glandular cells: 9.3;Endometrial luminal cells: 8.8;Epididymal basal cells: 4.6;Epididymal principal cells: 9.0;Lacrimal acinar cells: 4.5;Pericytes: 16.5;Respiratory ionocytes: 5.1;Retinal pigment epithelial cells: 8.5;Vascular smooth muscle cells: 9.0" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 2.1;eccentric medium spiny neuron: 1.9;medium spiny neuron: 1.8;vascular associated smooth muscle cell: 2.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "basal ganglia: 2.5;cerebellum: 1.0;thalamus: 3.2" "Low region specificity" "Detected in many" "HPA066029, HPA074948" Approved Supported Vesicles,Cytosol NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 15: Kidney cancer - Membrane components" "Cluster 110: Mural cells - ECM organization" 3 Vesicles Cytosol "HPA066029: , HPA074948: " "unprognostic (9.15e-3)" "unprognostic (2.65e-3)" "validated prognostic favorable (3.02e-4)" "validated prognostic favorable (7.50e-7)" "unprognostic (2.27e-2)" "unprognostic (9.88e-3)" "unprognostic (2.19e-1)" ADRA2C "ADRA2L2, ADRA2RL2, ADRARL2" ENSG00000184160 "Adrenoceptor alpha 2C" P18825 4 3766348-3768526 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 101.9;cervix: 60.5;endometrium 1: 54.2" "Cell type enhanced" "Detected in some" "Decidual stromal cells: 56.7;Endometrial stromal cells: 109.6;Fallopian secretory cells: 27.9;Fibroblasts: 18.5;Pericytes: 27.8;Retinal pigment epithelial cells: 29.8;Smooth muscle cells: 40.6;Vascular smooth muscle cells: 45.8" "Cell type enhanced" "Detected in many" "fibroblast: 19.1;pericyte: 42.4" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 30.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 18.1" "Adipose subcutaneous - Smooth muscle cells, Breast - Endothelial cells, Minor Salivary Gland - Endothelial cells, Spleen - Fibroblasts_2, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 6 "basal ganglia: 45.2" HPA057688 Uncertain NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 33: Neurons - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 62: Smooth muscle cells - Muscle contraction" 10 "HPA057688: " "unprognostic (7.13e-2)" "unprognostic (2.93e-2)" "unprognostic (5.24e-2)" "unprognostic (1.37e-2)" "unprognostic (1.13e-1)" "unprognostic (6.62e-2)" "unprognostic (6.00e-2)" "unprognostic (6.62e-2)" "unprognostic (5.71e-2)" "unprognostic (8.75e-3)" "unprognostic (1.63e-1)" "unprognostic (2.37e-2)" "unprognostic (3.49e-2)" "unprognostic (1.82e-2)" "unprognostic (1.44e-1)" "unprognostic (1.34e-1)" "unprognostic (1.10e-1)" "unprognostic (1.99e-2)" "unprognostic (1.29e-1)" "unprognostic (2.95e-2)" "unprognostic (2.62e-1)" "unprognostic (2.13e-1)" "unprognostic (2.47e-1)" "unprognostic (3.98e-2)" "unprognostic (1.89e-1)" "unprognostic (1.10e-1)" "unprognostic (1.18e-2)" ADRB1 ADRB1R ENSG00000043591 "Adrenoceptor beta 1" P08588 10 114043866-114046904 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 20.3;lung: 11.4;placenta: 27.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 36.3;Astrocytes: 20.3;Cytotrophoblasts: 99.7;Migrating cytotrophoblasts: 57.1;Respiratory ciliated cells: 34.8;Respiratory ionocytes: 43.2;Syncytiotrophoblasts: 36.8" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Kidney Chromophobe (TCGA): 4.9;Prostate Adenocarcinoma (TCGA): 15.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Bone cancer: 7.9" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Intercalated cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA067972 Enhanced NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 53: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 7 "HPA067972: " "unprognostic (6.91e-3)" "unprognostic (1.45e-3)" "unprognostic (2.88e-3)" "potential prognostic unfavorable (3.97e-4)" "unprognostic (2.39e-1)" "unprognostic (1.21e-1)" "unprognostic (9.13e-3)" "unprognostic (4.93e-3)" "unprognostic (8.06e-2)" "unprognostic (2.72e-2)" "unprognostic (9.33e-2)" "unprognostic (8.22e-2)" "unprognostic (5.76e-2)" "unprognostic (7.28e-2)" ADRB2 "ADRB2R, ADRBR, B2AR, BAR" ENSG00000169252 "Adrenoceptor beta 2" P07550 5 148826611-148828623 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 32.4;skin 1: 36.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 175.2;Basal keratinocytes: 326.3;Breast lactating cells: 230.8;Conjunctival goblet cells: 70.9;Mast cells: 138.8;Ocular epithelial cells: 152.7;Suprabasal keratinocytes: 184.6" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 63.3;leukocyte: 27.5" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 22.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "head and neck cancer: 50.9" "Colon - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075322 Supported "Plasma membrane,Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Basal body" Yes NA "Cluster 25: Non-specific - Unknown function" "Cluster 58: Skin - Keratinization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 26: Keratinocytes - Keratinization" 88 "Plasma membrane" "Microtubules, Cytokinetic bridge, Mitotic spindle, Primary cilium, Basal body" "HPA075322: " "unprognostic (4.34e-2)" "unprognostic (4.20e-2)" "unprognostic (1.49e-1)" "unprognostic (5.93e-2)" "unprognostic (1.66e-2)" "unprognostic (2.46e-1)" "unprognostic (1.31e-2)" "unprognostic (2.35e-1)" "unprognostic (5.14e-3)" "potential prognostic favorable (6.64e-7)" "unprognostic (3.59e-2)" "unprognostic (1.34e-3)" "unprognostic (1.11e-2)" "potential prognostic favorable (8.63e-4)" "unprognostic (4.60e-3)" "unprognostic (1.35e-1)" "unprognostic (4.01e-2)" "unprognostic (1.19e-1)" "unprognostic (2.08e-2)" "unprognostic (7.70e-3)" "unprognostic (2.20e-1)" "unprognostic (2.45e-2)" "unprognostic (1.48e-1)" "unprognostic (3.00e-2)" "unprognostic (5.62e-2)" "unprognostic (1.16e-1)" ADRB3 ENSG00000188778 "Adrenoceptor beta 3" P13945 8 37962990-37966599 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Diabetes mellitus, FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 5.3;ovary: 12.8;urinary bladder: 5.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 169 "Bone cancer: 17.7" "Breast - Adipocytes (Breast), Prostate - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA061969, HPA065408" Uncertain Uncertain "Vesicles,Basal body" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 105: Non-specific - Mixed function" 1 "Vesicles, Basal body" "HPA061969: , HPA065408: " ADRM1 "ARM1, GP110, PSMD16, Rpn13" ENSG00000130706 "ADRM1 26S proteasome ubiquitin receptor" Q16186 20 62302093-62308862 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 376.2" "Cell type enriched" "Detected in all" 4 "Late spermatids: 2560.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042266 Supported Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 230000 "Cluster 25: Non-specific - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 91 "Nucleoplasm, Plasma membrane, Cytosol" "HPA042266: " "unprognostic (5.12e-3)" "unprognostic (6.16e-3)" "unprognostic (1.03e-1)" "unprognostic (2.54e-1)" "unprognostic (2.15e-1)" "unprognostic (5.78e-2)" "unprognostic (1.70e-2)" "unprognostic (1.20e-1)" "unprognostic (3.02e-1)" "unprognostic (4.96e-3)" "potential prognostic unfavorable (6.08e-6)" "unprognostic (4.90e-3)" "unprognostic (7.51e-2)" "potential prognostic unfavorable (3.25e-5)" "unprognostic (2.03e-3)" "unprognostic (1.11e-2)" "unprognostic (5.34e-2)" "unprognostic (6.60e-2)" "unprognostic (2.41e-1)" "unprognostic (9.87e-2)" "unprognostic (6.33e-2)" "unprognostic (2.63e-1)" "unprognostic (1.23e-1)" "unprognostic (9.06e-2)" "unprognostic (5.06e-2)" "unprognostic (5.79e-3)" "unprognostic (2.32e-2)" "unprognostic (2.34e-1)" "unprognostic (2.52e-1)" "unprognostic (1.93e-1)" "unprognostic (9.62e-2)" ADSL ENSG00000239900 "Adenylosuccinate lyase" P30566 22 40346461-40390463 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Purine biosynthesis" Lyase "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "skeletal muscle: 323.5;tongue: 226.5" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 25.0;Enteric stem cells: 30.9;Enteric transient amplifying cells: 33.7;Oocytes: 41.4;Paneth cells: 30.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Endothelial cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000525, CAB019285" Enhanced Enhanced Cytosol NA NA 320000 "Cluster 33: Non-specific - ATP binding" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 66: Non-specific - Mitochondria" "Cluster 15: Non-specific - Protein processing" 6 Cytosol "CAB019285: , HPA000525: " "unprognostic (7.10e-3)" "unprognostic (8.33e-2)" "unprognostic (2.40e-1)" "unprognostic (1.81e-1)" "unprognostic (2.47e-2)" "unprognostic (1.85e-1)" "unprognostic (1.44e-2)" "unprognostic (9.73e-2)" "unprognostic (3.10e-3)" "unprognostic (6.22e-3)" "potential prognostic favorable (3.05e-6)" "unprognostic (4.62e-3)" "unprognostic (1.41e-1)" "validated prognostic unfavorable (9.44e-7)" "validated prognostic unfavorable (9.84e-8)" "unprognostic (1.20e-2)" "potential prognostic unfavorable (7.65e-4)" "unprognostic (7.34e-2)" "unprognostic (1.23e-2)" "unprognostic (1.44e-1)" "unprognostic (2.55e-2)" "unprognostic (2.92e-2)" "unprognostic (1.18e-1)" "unprognostic (2.72e-1)" "unprognostic (1.68e-3)" "unprognostic (8.41e-2)" "unprognostic (4.91e-1)" "unprognostic (5.00e-2)" "unprognostic (3.74e-1)" "unprognostic (1.47e-1)" "unprognostic (2.17e-1)" ADSS1 "ADSSL1, FLJ38602" ENSG00000185100 "Adenylosuccinate synthase 1" Q8N142 14 104724229-104747325 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Purine biosynthesis" Ligase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "skeletal muscle: 1192.9;tongue: 569.7" "Cell type enhanced" "Detected in many" "Early spermatids: 478.1;Late primary spermatocytes: 297.4;Late spermatids: 127.5;Müller glia: 59.8;Myonuclei: 75.1;Thymic myoid cells: 205.3" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in all" 4 "Kidney Renal Clear Cell Carcinoma (TCGA): 55.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052621 Enhanced NA NA 150000 "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 45: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 5 "HPA052621: " "unprognostic (8.64e-3)" "unprognostic (1.19e-1)" "unprognostic (2.56e-1)" "unprognostic (2.16e-2)" "unprognostic (7.59e-2)" "unprognostic (5.12e-3)" "potential prognostic unfavorable (4.35e-4)" "unprognostic (2.60e-1)" "unprognostic (1.80e-1)" "unprognostic (3.30e-3)" "potential prognostic favorable (6.03e-4)" "unprognostic (3.51e-1)" "unprognostic (3.00e-2)" "unprognostic (1.87e-3)" "unprognostic (1.56e-2)" "unprognostic (2.03e-1)" "unprognostic (3.09e-2)" "unprognostic (2.17e-1)" "unprognostic (7.60e-2)" "unprognostic (5.14e-2)" "unprognostic (1.48e-3)" "unprognostic (3.32e-1)" "unprognostic (1.74e-1)" "unprognostic (2.08e-1)" "unprognostic (8.22e-2)" "unprognostic (5.04e-2)" "unprognostic (2.07e-1)" "unprognostic (3.03e-2)" "unprognostic (2.92e-3)" ADSS2 ADSS ENSG00000035687 "Adenylosuccinate synthase 2" P30520 1 244408494-244451909 "Enzymes, Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Purine biosynthesis" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 215.1;Neutrophil progenitors: 726.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024400 Supported Approved "Plasma membrane,Cytosol" NA NA 500000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 15 Cytosol "Plasma membrane" "HPA024400: " "unprognostic (1.08e-1)" "unprognostic (2.33e-2)" "unprognostic (1.35e-1)" "unprognostic (1.11e-2)" "unprognostic (2.15e-1)" "unprognostic (1.19e-1)" "unprognostic (4.94e-2)" "unprognostic (1.22e-1)" "unprognostic (7.72e-2)" "potential prognostic favorable (6.04e-4)" "unprognostic (2.35e-1)" "unprognostic (2.24e-2)" "unprognostic (1.97e-2)" "unprognostic (5.96e-3)" "unprognostic (9.89e-3)" "unprognostic (1.35e-2)" "unprognostic (3.18e-1)" "unprognostic (1.45e-2)" "unprognostic (4.83e-2)" "unprognostic (4.41e-3)" "unprognostic (4.01e-2)" "unprognostic (1.05e-1)" "unprognostic (3.20e-2)" "unprognostic (1.29e-1)" "unprognostic (1.59e-1)" "unprognostic (1.99e-1)" "unprognostic (2.88e-1)" "unprognostic (1.78e-1)" "unprognostic (3.92e-1)" ADTRP "AIG1L, C6orf105, dJ413H6.1" ENSG00000111863 "Androgen dependent TFPI regulating protein" Q96IZ2 6 11712054-11807046 "Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 97.8;intestine: 92.7;parathyroid gland: 87.2" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 115.1;Colonocytes: 156.4;Early spermatids: 195.5;Enteric transient amplifying cells: 78.9;Enterocytes: 199.2;Foveolar cells: 166.3;Late primary spermatocytes: 97.1;Late spermatids: 372.1;Parietal cells: 104.3;Renal collecting duct intercalated cells: 208.6;Retinal pigment epithelial cells: 311.2" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 111.0;deep-layer corticothalamic and 6b: 88.2;deep-layer near-projecting: 55.0" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 10 "choroid plexus: 79.3" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 14.8;T-reg: 13.6" "Lineage enriched" "Detected in many" 5 "T-cells: 14.8" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Skin - Sebaceous gland cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA048113 Uncertain Uncertain Nucleoli NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 2 Nucleoli "HPA048113: " "unprognostic (6.02e-3)" "unprognostic (6.11e-3)" "unprognostic (2.91e-3)" "unprognostic (8.57e-2)" "unprognostic (7.79e-2)" "unprognostic (9.78e-3)" "unprognostic (9.30e-2)" "potential prognostic unfavorable (3.05e-4)" "unprognostic (4.89e-3)" "unprognostic (2.83e-2)" "unprognostic (5.45e-3)" "unprognostic (4.07e-2)" "unprognostic (1.52e-1)" "unprognostic (3.86e-2)" "unprognostic (1.19e-2)" "unprognostic (3.10e-1)" "unprognostic (9.28e-2)" "unprognostic (6.60e-3)" "unprognostic (1.13e-1)" "unprognostic (2.29e-1)" "unprognostic (7.25e-2)" "unprognostic (7.81e-3)" "unprognostic (2.19e-1)" "unprognostic (8.90e-3)" "unprognostic (2.30e-1)" "unprognostic (2.74e-2)" "unprognostic (7.46e-3)" AEBP1 ACLP ENSG00000106624 "AE binding protein 1" Q8IUX7 7 44104345-44114562 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Transcription, Transcription regulation" "Calmodulin-binding, DNA-binding, Repressor" "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "blood vessel: 1145.3" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 124.5;Endometrial stromal cells: 85.5;Fibroblasts: 307.2;Hepatic stellate cells: 167.8;Leydig cells: 150.7;Melanocytes: 129.5;Ovarian stromal cells: 149.9;Pericytes: 162.0;Peritubular myoid cells: 560.3;Smooth muscle cells: 109.2;Vascular smooth muscle cells: 246.1" "Group enriched" "Detected in many" 13 "astrocyte: 112.8;ependymal cell: 79.3;fibroblast: 153.2;vascular associated smooth muscle cell: 173.4" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 691.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "plasmacytoid DC: 7.6" "Lineage enriched" "Detected in many" 5 "dendritic cells: 7.6" "Cancer enhanced" "Detected in many" "skin cancer: 76.4" "Adipose visceral - Adipose progenitor cells, Adrenal gland - Fibroblasts, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Prostate - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 77.4" "CAB009966, HPA047724, HPA063595, HPA064970" Supported Supported Nucleoplasm,Vesicles,Cytosol "Secreted - unknown location" Transcription NA NA 54000000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 108: Fibroblasts - ECM organization" Vesicles "Nucleoplasm, Cytosol" "CAB009966: , HPA047724: , HPA063595: , HPA064970: " "unprognostic (2.79e-3)" "unprognostic (6.47e-2)" "unprognostic (2.55e-2)" "unprognostic (2.82e-2)" "unprognostic (9.68e-3)" "unprognostic (1.55e-1)" "validated prognostic unfavorable (7.67e-5)" "validated prognostic unfavorable (1.18e-4)" "unprognostic (9.44e-2)" "unprognostic (5.99e-3)" "unprognostic (2.02e-1)" "unprognostic (8.19e-3)" "potential prognostic unfavorable (7.98e-5)" "unprognostic (1.31e-1)" "unprognostic (2.95e-2)" "unprognostic (8.31e-2)" "unprognostic (9.11e-2)" "unprognostic (3.93e-2)" "unprognostic (2.25e-1)" "unprognostic (2.63e-3)" "unprognostic (9.07e-3)" "unprognostic (1.46e-1)" "unprognostic (8.25e-2)" "unprognostic (2.64e-1)" "unprognostic (2.51e-2)" "unprognostic (1.00e-2)" "unprognostic (1.45e-1)" "unprognostic (7.84e-3)" "unprognostic (5.25e-2)" "unprognostic (8.10e-2)" "unprognostic (2.50e-1)" AEBP2 MGC17922 ENSG00000139154 "AE binding protein 2" Q6ZN18 12 19404045-19720801 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Choroid plexus epithelial cells: 455.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020893, HPA022282" Uncertain Enhanced Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 29: Forebrain - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 35: Neurons - Synaptic function & neurogenesis" 20 Nucleoplasm "HPA020893: , HPA022282: " "unprognostic (1.60e-1)" "unprognostic (3.65e-2)" "unprognostic (2.33e-2)" "unprognostic (1.31e-1)" "unprognostic (7.98e-2)" "unprognostic (5.79e-2)" "unprognostic (4.06e-2)" "unprognostic (1.03e-1)" "unprognostic (4.92e-2)" "unprognostic (1.10e-2)" "potential prognostic favorable (1.93e-5)" "unprognostic (7.75e-3)" "unprognostic (8.12e-2)" "unprognostic (6.95e-3)" "unprognostic (4.55e-2)" "unprognostic (5.50e-2)" "unprognostic (4.93e-2)" "unprognostic (1.56e-2)" "unprognostic (3.30e-1)" "unprognostic (2.38e-3)" "unprognostic (4.41e-3)" "unprognostic (2.20e-2)" "unprognostic (2.92e-3)" "unprognostic (2.13e-1)" "unprognostic (6.98e-3)" "unprognostic (1.31e-3)" "unprognostic (1.27e-2)" "unprognostic (3.47e-1)" "unprognostic (4.17e-1)" "unprognostic (1.00e-1)" "unprognostic (2.15e-1)" AEN "FLJ12484, FLJ12562, ISG20L1" ENSG00000181026 "Apoptosis enhancing nuclease" Q8WTP8 15 88621337-88632281 "Predicted intracellular proteins" "Apoptosis, DNA damage" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late spermatids: 95.9" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 110.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048599 Supported Nucleoplasm,Nucleoli NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 70: Non-specific - Protein processing" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 55: Lymphoma - Immune response" "Cluster 17: Non-specific - RNA processing" 30 "Nucleoplasm, Nucleoli" "HPA048599: " "unprognostic (3.03e-1)" "unprognostic (2.83e-1)" "unprognostic (3.49e-1)" "unprognostic (1.14e-1)" "unprognostic (2.72e-1)" "unprognostic (1.18e-1)" "unprognostic (3.73e-2)" "unprognostic (3.82e-2)" "unprognostic (1.04e-2)" "unprognostic (1.51e-1)" "potential prognostic favorable (2.36e-4)" "unprognostic (2.89e-2)" "unprognostic (2.14e-2)" "unprognostic (7.17e-2)" "unprognostic (1.32e-1)" "unprognostic (3.63e-2)" "unprognostic (6.20e-2)" "unprognostic (8.71e-2)" "potential prognostic favorable (6.61e-4)" "unprognostic (8.01e-2)" "unprognostic (8.20e-2)" "unprognostic (7.29e-2)" "unprognostic (1.18e-1)" "unprognostic (5.88e-2)" "unprognostic (5.04e-1)" "unprognostic (2.95e-2)" "unprognostic (2.50e-1)" "unprognostic (1.29e-2)" "unprognostic (1.72e-1)" "unprognostic (1.12e-2)" "unprognostic (2.02e-1)" AFAP1 "AFAP, AFAP-110" ENSG00000196526 "Actin filament associated protein 1" Q8N556 4 7758714-7939926 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 220.6;Epicardial cells: 186.5;Extravillous trophoblasts: 367.6;Late spermatids: 643.5;Oligodendrocyte progenitor cells: 204.0;Somatotrophs: 389.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 2.5" "Group enriched" "Detected in many" 5 "granulocytes: 2.5;T-cells: 1.0" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015642, CAB024712" Enhanced Supported "Actin filaments,Focal adhesion sites,Cytosol" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 51: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 4 "Actin filaments" "Focal adhesion sites, Cytosol" "CAB024712: , HPA015642: " "unprognostic (6.59e-2)" "unprognostic (1.86e-2)" "unprognostic (1.22e-2)" "unprognostic (3.37e-2)" "unprognostic (2.04e-1)" "unprognostic (5.16e-2)" "unprognostic (1.74e-1)" "unprognostic (4.44e-2)" "unprognostic (2.00e-1)" "unprognostic (2.69e-1)" "potential prognostic favorable (7.19e-4)" "unprognostic (2.00e-3)" "unprognostic (6.75e-3)" "unprognostic (2.08e-1)" "unprognostic (2.89e-1)" "potential prognostic unfavorable (1.62e-4)" "unprognostic (2.07e-3)" "unprognostic (7.01e-3)" "unprognostic (4.98e-2)" "unprognostic (3.67e-2)" "unprognostic (5.78e-3)" "unprognostic (5.57e-3)" "unprognostic (1.06e-2)" "unprognostic (2.09e-1)" "unprognostic (5.12e-2)" "unprognostic (1.98e-2)" "unprognostic (5.00e-1)" "unprognostic (2.57e-2)" "unprognostic (2.53e-1)" "unprognostic (2.77e-2)" "unprognostic (2.59e-1)" AFAP1L1 FLJ36748 ENSG00000157510 "Actin filament associated protein 1 like 1" Q8TED9 5 149271859-149343637 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 24.4;skeletal muscle: 29.6" "Cell type enhanced" "Detected in many" "Adipocytes: 89.8;Cardiomyocytes: 61.9;Early spermatids: 156.7;Extravillous trophoblasts: 109.1;Late spermatids: 67.3;Lymphatic endothelial cells: 230.1;Medullary thymic epithelial cells: 81.6;Myonuclei: 57.8;Thymic myoid cells: 65.3;Vascular endothelial cells: 129.3" "Group enriched" "Detected in many" 10 "endothelial cell: 110.3;fibroblast: 45.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Lung - Endothelial cells, Minor Salivary Gland - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Stomach - Endothelial cells, Thyroid gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 69: Skin cancer - ECM organization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 4 "unprognostic (2.70e-1)" "unprognostic (2.53e-1)" "unprognostic (2.59e-1)" "unprognostic (8.70e-2)" "unprognostic (1.90e-2)" "unprognostic (1.27e-1)" "unprognostic (3.29e-1)" "unprognostic (1.49e-3)" "unprognostic (9.42e-2)" "unprognostic (1.44e-1)" "validated prognostic favorable (3.70e-8)" "validated prognostic favorable (3.57e-4)" "unprognostic (9.98e-2)" "unprognostic (1.64e-1)" "unprognostic (1.26e-1)" "unprognostic (7.00e-2)" "unprognostic (7.70e-3)" "unprognostic (9.84e-2)" "unprognostic (2.34e-1)" "unprognostic (2.32e-1)" "unprognostic (1.84e-2)" "unprognostic (2.58e-2)" "potential prognostic unfavorable (4.53e-6)" "unprognostic (2.27e-2)" "unprognostic (2.16e-1)" "unprognostic (4.41e-2)" "unprognostic (7.00e-2)" "unprognostic (7.96e-3)" "unprognostic (1.69e-1)" "unprognostic (3.01e-2)" "unprognostic (6.52e-2)" AFAP1L2 "Em:AC005383.4, FLJ14564, KIAA1914, XB130" ENSG00000169129 "Actin filament associated protein 1 like 2" Q8N4X5 10 114294824-114404756 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 60.8;parathyroid gland: 64.6;thyroid gland: 77.0" "Cell type enhanced" "Detected in many" "Oligodendrocyte progenitor cells: 213.7;Podocytes: 126.7;Renal collecting duct principal cells: 135.6;Renal connecting tubule cells: 112.9;Schwann cells: 130.9;Tuft cells: 265.1" "Group enriched" "Detected in many" 6 "committed oligodendrocyte precursor: 171.8;endothelial cell: 254.2;oligodendrocyte precursor cell: 253.0;pericyte: 117.4;vascular associated smooth muscle cell: 104.9" "Cancer enhanced" "Detected in all" "Thyroid Carcinoma (TCGA): 82.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 1.6;T-cells: 1.8" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Liver - Hepatic stellate cells, Skin - Outer root sheath cells, Spleen - Endothelial cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 102.6" HPA037843 Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 33: Thyroid gland - Tissue development" "Cluster 15: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 104: Brain endothelial cells - Blood brain barrier" 1 Cytosol "Plasma membrane" "HPA037843: " "unprognostic (1.63e-2)" "unprognostic (9.10e-3)" "unprognostic (3.96e-2)" "unprognostic (2.77e-2)" "unprognostic (8.02e-2)" "unprognostic (2.88e-1)" "unprognostic (2.18e-2)" "unprognostic (1.61e-1)" "unprognostic (1.38e-1)" "unprognostic (4.30e-1)" "potential prognostic favorable (1.77e-4)" "unprognostic (3.81e-3)" "potential prognostic unfavorable (3.75e-4)" "unprognostic (2.28e-1)" "unprognostic (1.54e-1)" "unprognostic (9.87e-2)" "unprognostic (3.04e-2)" "unprognostic (5.34e-3)" "unprognostic (1.19e-3)" "unprognostic (9.70e-3)" "unprognostic (2.03e-3)" "potential prognostic unfavorable (1.22e-4)" "unprognostic (6.38e-2)" "unprognostic (2.32e-1)" "unprognostic (7.44e-2)" "unprognostic (5.60e-2)" "unprognostic (2.17e-1)" "unprognostic (4.84e-2)" "unprognostic (6.82e-2)" "unprognostic (1.73e-1)" "unprognostic (5.43e-2)" AFDN "AF-6, AF6, MLLT4" ENSG00000130396 "Afadin, adherens junction formation factor" P55196 6 167826893-167972023 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Cell adhesion" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 840.1;Endometrial glandular cells: 1110.5;Esophageal apical cells: 1778.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Heart muscle - Endothelial cells, Lung - Alveolar cells type 1, Skeletal muscle - Endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013496, HPA030212, HPA030213, HPA030214, HPA030215, HPA049868" Approved Enhanced "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 82: Salivary gland - Secretion" "Cluster 6: Non-specific - Immune response" "Cluster 72: Neuronal - Signal transduction" "Cluster 51: Secretory epithelial cells - Mixed function" 56 "Plasma membrane, Cell Junctions" Nucleoplasm "CAB013496: , HPA030212: , HPA030213: , HPA030214: , HPA030215: , HPA049868: " "unprognostic (8.10e-2)" "potential prognostic unfavorable (4.57e-5)" "potential prognostic unfavorable (1.36e-4)" "unprognostic (1.17e-1)" "unprognostic (3.78e-1)" "unprognostic (1.51e-1)" "unprognostic (8.44e-2)" "unprognostic (1.21e-1)" "unprognostic (7.86e-2)" "potential prognostic favorable (1.65e-5)" "unprognostic (3.47e-3)" "unprognostic (2.02e-2)" "unprognostic (2.56e-1)" "unprognostic (1.77e-1)" "unprognostic (1.08e-1)" "unprognostic (1.05e-1)" "unprognostic (2.19e-2)" "potential prognostic unfavorable (1.79e-4)" "unprognostic (3.06e-1)" "unprognostic (1.26e-1)" "unprognostic (5.74e-3)" "unprognostic (1.39e-1)" "unprognostic (1.64e-2)" "unprognostic (6.35e-2)" "unprognostic (8.20e-2)" "unprognostic (9.55e-3)" "unprognostic (3.21e-1)" "unprognostic (1.27e-2)" "unprognostic (1.20e-1)" AFF1 "AF-4, AF4, FEL, MLLT2, PBM1" ENSG00000172493 "ALF transcription elongation factor 1" P51825 4 86935002-87141039 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 1283.5;Renal collecting duct principal cells: 1628.5;Syncytiotrophoblasts: 1153.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069947 Approved Nucleoplasm,Mitochondria No No "Cluster 7: Non-specific - Innate immune response" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 18 "Nucleoplasm, Mitochondria" "HPA069947: " "unprognostic (1.63e-2)" "unprognostic (1.01e-1)" "unprognostic (1.60e-1)" "unprognostic (7.40e-3)" "unprognostic (6.36e-2)" "unprognostic (1.82e-1)" "unprognostic (8.73e-2)" "unprognostic (2.39e-1)" "unprognostic (2.31e-2)" "potential prognostic unfavorable (4.05e-4)" "validated prognostic favorable (4.81e-6)" "validated prognostic favorable (5.19e-4)" "unprognostic (6.38e-2)" "unprognostic (6.53e-2)" "unprognostic (6.29e-2)" "unprognostic (3.43e-1)" "unprognostic (2.33e-2)" "unprognostic (1.71e-2)" "unprognostic (3.74e-2)" "unprognostic (4.13e-2)" "unprognostic (4.91e-2)" "unprognostic (8.86e-2)" "unprognostic (3.09e-3)" "unprognostic (3.12e-2)" "unprognostic (1.32e-3)" "unprognostic (1.49e-2)" "unprognostic (1.03e-1)" "unprognostic (1.54e-2)" "unprognostic (2.08e-1)" "unprognostic (1.17e-1)" "unprognostic (5.27e-2)" AFF2 "FMR2, FRAXE" ENSG00000155966 "ALF transcription elongation factor 2" P51816 X 148500617-149000663 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 11.3;epididymis: 11.2;placenta: 13.8" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 141.6;Cone photoreceptor cells: 238.1;Lactotrophs: 364.3;Neutrophil progenitors: 659.3;Pituicytes/FSCs: 466.8;Rod photoreceptor cells: 211.2;Sertoli cells: 170.2;Somatotrophs: 355.5;Thyrotrophs: 341.2" "Cell type enhanced" "Detected in all" "hippocampal CA4: 499.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "eosinophil: 1.0;neutrophil: 1.5" "Lineage enriched" "Detected in single" 12 "granulocytes: 1.5" "Group enriched" "Detected in some" 4 "Leukemia: 7.8;lymphoma: 16.5" "Adipose visceral - Adipocytes (Visceral), Adrenal gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003139 Approved NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 40: Non-specific - Mixed function" "Cluster 29: Forebrain - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" "HPA003139: " "unprognostic (1.18e-3)" "potential prognostic favorable (5.08e-5)" "unprognostic (4.73e-3)" "unprognostic (5.29e-2)" "unprognostic (2.33e-2)" "unprognostic (9.46e-2)" "unprognostic (3.06e-2)" "unprognostic (5.96e-3)" "unprognostic (7.67e-2)" "unprognostic (3.18e-2)" "unprognostic (3.19e-1)" "unprognostic (1.30e-2)" "unprognostic (1.01e-1)" "unprognostic (4.68e-2)" AFF3 "LAF4, MLLT2-like" ENSG00000144218 "ALF transcription elongation factor 3" P51826 2 99545419-100192428 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 1048.9;B-cells: 2597.4;Breast hormone-responsive cells: 1980.4;Innate lymphoid cells: 1467.6;Lactotrophs: 1053.7;pDCs: 1418.7;Prostatic glandular cells: 3187.8;Retinal amacrine cells: 1077.9;Somatotrophs: 983.3;Thymocytes: 1364.4;Thyrotrophs: 2194.3" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Breast Invasive Carcinoma (TCGA): 29.5;Prostate Adenocarcinoma (TCGA): 17.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "memory B-cell: 31.0;naive B-cell: 44.1;plasmacytoid DC: 23.8" "Group enriched" "Detected in many" 17 "B-cells: 44.1;dendritic cells: 23.8" "Cancer enhanced" "Detected in many" "lymphoma: 22.6" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Kidney - Fibroblasts, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Lactotropes, Prostate - Prostate glandular cells, Skeletal muscle - Fibroblasts, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044512, HPA053379" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 61: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 2 Nucleoplasm Cytosol "HPA044512: , HPA053379: " "unprognostic (1.30e-1)" "unprognostic (4.83e-2)" "unprognostic (3.49e-2)" "unprognostic (1.67e-1)" "unprognostic (1.01e-1)" "potential prognostic favorable (1.02e-6)" "unprognostic (5.02e-3)" "potential prognostic unfavorable (7.05e-4)" "potential prognostic unfavorable (6.08e-4)" "unprognostic (1.72e-1)" "unprognostic (8.58e-3)" "unprognostic (3.45e-2)" "unprognostic (1.32e-1)" "unprognostic (1.17e-1)" "unprognostic (2.09e-1)" "unprognostic (6.72e-2)" "unprognostic (3.27e-2)" "unprognostic (5.21e-2)" "unprognostic (7.33e-2)" "unprognostic (1.84e-1)" AFF4 "AF5Q31, MCEF" ENSG00000072364 "ALF transcription elongation factor 4" Q9UHB7 5 132875395-132963634 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Cancer-related genes, Disease variant, Dwarfism, Obesity, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023690, HPA029634, HPA076229" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Nuclear bodies" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 28: Liver & Adrenal gland - Secretion" "Cluster 31: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 39 Nucleoplasm "Nucleoli fibrillar center, Nuclear bodies" "HPA023690: , HPA029634: , HPA076229: " "unprognostic (9.93e-3)" "unprognostic (1.99e-2)" "unprognostic (7.60e-2)" "unprognostic (3.58e-2)" "unprognostic (3.41e-2)" "unprognostic (4.22e-2)" "unprognostic (2.25e-1)" "unprognostic (2.67e-1)" "unprognostic (1.13e-1)" "potential prognostic unfavorable (7.35e-5)" "potential prognostic favorable (6.29e-9)" "unprognostic (2.23e-3)" "unprognostic (2.80e-1)" "unprognostic (1.22e-1)" "unprognostic (2.02e-3)" "unprognostic (2.40e-1)" "unprognostic (1.30e-1)" "unprognostic (8.96e-2)" "unprognostic (9.30e-2)" "unprognostic (2.94e-2)" "unprognostic (2.99e-3)" "unprognostic (1.95e-2)" "unprognostic (1.22e-3)" "unprognostic (1.40e-1)" "unprognostic (8.63e-2)" "unprognostic (1.74e-1)" "unprognostic (1.40e-1)" "unprognostic (3.71e-2)" "unprognostic (1.53e-1)" "unprognostic (8.55e-3)" "unprognostic (1.22e-1)" AFG1L "AFG1, LACE1" ENSG00000135537 "AFG1 like ATPase" Q8WV93 6 108294991-108526796 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 10.3" "Cell type enhanced" "Detected in many" "Early spermatids: 754.5;Late primary spermatocytes: 500.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030154, HPA030155, HPA030659" Approved "Intracellular and membrane" Enzyme NA NA "Cluster 18: Non-specific - Translation" "Cluster 76: Non-specific - Metabolism" "Cluster 53: Neurons - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 2 "HPA030154: , HPA030155: , HPA030659: " "unprognostic (3.71e-2)" "potential prognostic unfavorable (4.59e-4)" "unprognostic (5.91e-2)" "unprognostic (3.99e-2)" "unprognostic (4.64e-2)" "unprognostic (8.41e-2)" "unprognostic (2.74e-1)" "unprognostic (3.79e-2)" "unprognostic (2.08e-2)" "potential prognostic favorable (3.33e-6)" "unprognostic (6.20e-3)" "unprognostic (9.36e-3)" "unprognostic (2.10e-1)" "unprognostic (9.40e-2)" "unprognostic (3.69e-1)" "unprognostic (1.45e-1)" "unprognostic (1.86e-1)" "unprognostic (1.50e-2)" "unprognostic (3.06e-2)" "unprognostic (2.62e-1)" "unprognostic (4.40e-3)" "unprognostic (1.16e-1)" "unprognostic (2.13e-3)" "unprognostic (1.23e-1)" "unprognostic (2.80e-3)" "unprognostic (1.12e-1)" "unprognostic (2.01e-1)" "unprognostic (1.29e-2)" "unprognostic (2.37e-2)" AFG3L2 "SCA28, SPAX5" ENSG00000141385 "AFG3 like matrix AAA peptidase subunit 2" Q9Y4W6 18 12328944-12377227 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 96.6;tongue: 92.6" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004479, HPA004480" Enhanced Enhanced "Mitochondria,Perinuclear theca,Calyx,Connecting piece,Mid piece,Principal piece" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 52: Non-specific - Cellular respiration" "Cluster 44: Non-specific - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 97: Non-specific - Cellular respiration" 24 Mitochondria "Perinuclear theca, Calyx, Connecting piece, Mid piece, Principal piece" "HPA004479: , HPA004480: " "unprognostic (8.39e-2)" "unprognostic (1.75e-1)" "unprognostic (2.47e-1)" "unprognostic (1.11e-1)" "unprognostic (3.24e-2)" "unprognostic (4.43e-1)" "unprognostic (2.50e-1)" "unprognostic (1.89e-2)" "unprognostic (4.04e-3)" "unprognostic (6.81e-3)" "validated prognostic favorable (2.24e-11)" "validated prognostic favorable (5.25e-6)" "unprognostic (1.24e-3)" "unprognostic (1.12e-1)" "potential prognostic unfavorable (6.75e-6)" "unprognostic (5.12e-2)" "unprognostic (5.88e-2)" "unprognostic (1.22e-1)" "unprognostic (4.01e-2)" "unprognostic (1.57e-1)" "unprognostic (2.61e-1)" "unprognostic (2.81e-2)" "unprognostic (1.22e-1)" "unprognostic (7.18e-2)" "unprognostic (2.36e-2)" "unprognostic (2.12e-2)" "unprognostic (4.42e-2)" "unprognostic (2.42e-1)" "unprognostic (2.78e-1)" "unprognostic (5.03e-3)" "unprognostic (3.97e-2)" AFM "ALB2, ALBA" ENSG00000079557 Afamin P43652 4 73481745-73504001 "Plasma proteins, Predicted secreted proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "liver: 898.8" "Group enriched" "Detected in some" 39 "Hepatocytes: 438.3;Proximal tubule cells: 123.2" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 91 "Liver Hepatocellular Carcinoma (TCGA): 87.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA017006, HPA052437" Enhanced Uncertain "Plasma membrane" "Secreted to blood" Transport NA NA 54900000000 19000000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 55: Lymphoma - Immune response" "Cluster 93: Hepatocytes - Bile production & excretion" 2 "Plasma membrane" "HPA017006: , HPA052437: " "potential prognostic favorable (7.22e-4)" "validated prognostic favorable (5.46e-5)" "validated prognostic favorable (1.18e-6)" AFMID "DKFZp686F03259, KF" ENSG00000183077 Arylformamidase Q63HM1 17 78187358-78207702 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Tryptophan catabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 166.7" "Cell type enhanced" "Detected in many" "Breast lactating cells: 151.3;Colonocytes: 223.6;Enterocytes: 230.5;Goblet cells: 140.8;Hepatocytes: 148.4;Proximal tubule cells: 250.1;Renal collecting duct principal cells: 173.1" "Group enriched" "Detected in many" 4 "committed oligodendrocyte precursor: 105.0;oligodendrocyte: 163.0;upper rhombic lip: 42.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 17.2" "Group enriched" "Detected in all" 5 "B-cells: 5.6;dendritic cells: 7.8;monocytes: 17.2" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA023861, HPA026536" Uncertain Approved Mitochondria NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 18: Liver cancer - Metabolism" "Cluster 65: Non-specific - Cell growth & division" 3 Mitochondria "HPA023861: , HPA026536: " "unprognostic (1.71e-2)" "unprognostic (4.14e-2)" "unprognostic (8.78e-2)" "unprognostic (9.00e-2)" "unprognostic (1.63e-1)" "unprognostic (8.84e-2)" "unprognostic (2.74e-1)" "unprognostic (1.08e-1)" "unprognostic (2.61e-2)" "unprognostic (2.30e-1)" "potential prognostic favorable (1.73e-4)" "unprognostic (3.91e-3)" "unprognostic (1.18e-1)" "unprognostic (6.45e-2)" "unprognostic (3.16e-1)" "unprognostic (2.45e-2)" "unprognostic (1.87e-1)" "unprognostic (2.84e-2)" "unprognostic (2.76e-3)" "unprognostic (4.60e-2)" "unprognostic (1.01e-1)" "unprognostic (1.09e-1)" "unprognostic (1.46e-1)" "unprognostic (9.50e-3)" "unprognostic (9.74e-2)" "unprognostic (3.63e-1)" "potential prognostic unfavorable (2.01e-4)" "unprognostic (1.45e-1)" "unprognostic (7.22e-2)" "unprognostic (2.30e-1)" "unprognostic (7.54e-2)" AFP "FETA, HPAFP" ENSG00000081051 "Alpha fetoprotein" P02771 4 73431138-73456174 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 10 "liver: 3.4" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 141.2" "Cell type enhanced" "Detected in single" "hippocampal CA4: 1.1" "Group enriched" "Detected in some" 16 "Liver Hepatocellular Carcinoma (TCGA): 235.4;Testicular Germ Cell Tumor (TCGA): 87.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "liver cancer: 642.2" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA010607, HPA023600, CAB024283, CAB025339, CAB080122" Approved Approved "Golgi apparatus" "Secreted to blood" "No annotated function" NA NA 3010000 3000000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 18: Liver cancer - Metabolism" "Cluster 93: Hepatocytes - Bile production & excretion" 6 "Golgi apparatus" "CAB024283: , CAB025339: , CAB080122: , HPA010607: , HPA023600: " "unprognostic (4.04e-1)" "unprognostic (1.27e-1)" "unprognostic (2.13e-1)" "unprognostic (4.96e-2)" "unprognostic (6.73e-3)" "unprognostic (6.89e-2)" AFTPH "FLJ20080, FLJ23793, MGC33965, Nbla10388" ENSG00000119844 Aftiphilin Q6ULP2 2 64524299-64593005 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 596.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034990, HPA034991" Approved Supported "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 55: Lymphoma - Immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 22 Cytosol "Golgi apparatus, Vesicles" "HPA034990: , HPA034991: " "unprognostic (4.19e-2)" "unprognostic (2.65e-2)" "unprognostic (6.00e-2)" "unprognostic (1.80e-1)" "unprognostic (1.07e-1)" "unprognostic (8.47e-2)" "unprognostic (3.14e-1)" "unprognostic (3.04e-2)" "unprognostic (3.37e-2)" "unprognostic (6.77e-2)" "potential prognostic favorable (1.08e-7)" "unprognostic (1.11e-3)" "unprognostic (2.17e-3)" "unprognostic (1.48e-2)" "unprognostic (1.69e-1)" "unprognostic (2.38e-1)" "unprognostic (3.53e-1)" "unprognostic (1.86e-2)" "unprognostic (6.58e-2)" "unprognostic (2.00e-1)" "unprognostic (6.95e-3)" "unprognostic (8.30e-2)" "unprognostic (1.88e-2)" "unprognostic (1.20e-1)" "unprognostic (1.45e-1)" "unprognostic (1.79e-1)" "unprognostic (1.03e-1)" "unprognostic (1.55e-1)" "unprognostic (1.79e-1)" "unprognostic (2.54e-1)" "unprognostic (1.08e-1)" AGA ASRG ENSG00000038002 Aspartylglucosaminidase P20933 4 177430774-177442437 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 151.3;Esophageal suprabasal cells: 68.5;Retinal pigment epithelial cells: 72.5" "Cell type enhanced" "Detected in all" "oligodendrocyte: 36.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031415, HPA031417" Enhanced "Intracellular and membrane" Enzyme NA NA 7800000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 22: Epididymis - Mixed function" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 63: Non-specific - Protein processing" "Cluster 78: Plasma cells - Antibody production & ER-stress response" 9 "HPA031415: , HPA031417: " "unprognostic (6.88e-2)" "unprognostic (9.91e-2)" "unprognostic (2.43e-2)" "unprognostic (2.76e-1)" "unprognostic (8.43e-2)" "unprognostic (1.78e-1)" "unprognostic (5.27e-2)" "unprognostic (2.11e-3)" "unprognostic (1.97e-3)" "unprognostic (4.13e-1)" "potential prognostic favorable (2.24e-4)" "unprognostic (8.03e-2)" "unprognostic (1.82e-1)" "potential prognostic unfavorable (1.91e-5)" "unprognostic (1.04e-2)" "unprognostic (3.85e-2)" "unprognostic (1.24e-1)" "unprognostic (2.11e-1)" "unprognostic (2.03e-1)" "unprognostic (9.07e-2)" "unprognostic (5.81e-2)" "unprognostic (8.51e-2)" "unprognostic (4.45e-1)" "unprognostic (1.16e-1)" "unprognostic (6.63e-2)" "unprognostic (4.09e-1)" "unprognostic (1.71e-2)" "unprognostic (8.55e-2)" "unprognostic (8.93e-2)" "unprognostic (2.84e-1)" "unprognostic (1.90e-2)" AGAP1 "CENTG2, GGAP1, KIAA1099" ENSG00000157985 "ArfGAP with GTPase domain, ankyrin repeat and PH domain 1" Q9UPQ3 2 235494043-236131793 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 43.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 3715.9;Oligodendrocyte progenitor cells: 2210.6;Oligodendrocytes: 1495.7;Retinal bipolar cells: 3563.8;Retinal horizontal cells: 1374.3;Rod photoreceptor cells: 1360.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 42: Retina - Visual perception" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 11 "unprognostic (3.38e-1)" "unprognostic (3.59e-3)" "unprognostic (4.83e-3)" "unprognostic (2.56e-2)" "unprognostic (1.20e-1)" "unprognostic (1.21e-1)" "unprognostic (4.56e-2)" "unprognostic (1.08e-1)" "unprognostic (1.29e-1)" "unprognostic (1.84e-2)" "validated prognostic favorable (1.08e-6)" "validated prognostic favorable (3.57e-4)" "unprognostic (6.61e-2)" "potential prognostic unfavorable (8.62e-4)" "unprognostic (3.25e-2)" "unprognostic (2.47e-1)" "unprognostic (2.53e-1)" "unprognostic (3.54e-1)" "unprognostic (7.73e-2)" "potential prognostic unfavorable (5.04e-4)" "unprognostic (1.33e-1)" "unprognostic (2.37e-1)" "unprognostic (3.02e-2)" "unprognostic (2.14e-1)" "unprognostic (5.30e-2)" "unprognostic (2.80e-2)" "unprognostic (2.35e-1)" "unprognostic (9.07e-2)" "unprognostic (3.58e-2)" "unprognostic (2.12e-1)" "unprognostic (1.26e-1)" AGAP2 CENTG1 ENSG00000135439 "ArfGAP with GTPase domain, ankyrin repeat and PH domain 2" Q99490 12 57723761-57742157 "Predicted intracellular proteins" "Protein transport, Transport" "GTPase activation" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 181.6" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 41.0;Brain inhibitory neurons: 35.4;Hematopoietic stem cells: 24.3;Neutrophil progenitors: 39.9;Neutrophils: 56.5;NK-cells: 21.5;Other brain neurons: 14.4;Pericytes: 29.6;Retinal amacrine cells: 18.2;T-cells: 20.9" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in all" 6 "Glioblastoma Multiforme (TCGA): 74.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Leukemia: 19.8" "Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023474, HPA075831" Enhanced Supported "Nucleoplasm,Midbody ring,Cytosol" Yes NA "Cluster 35: Neutrophils - Protein binding" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 11 "Nucleoplasm, Cytosol" "Midbody ring" "HPA023474: , HPA075831: " "unprognostic (1.25e-1)" "unprognostic (1.35e-3)" "potential prognostic favorable (8.17e-5)" "unprognostic (2.64e-2)" "unprognostic (1.60e-2)" "unprognostic (3.58e-2)" "unprognostic (5.04e-1)" "unprognostic (1.45e-3)" "unprognostic (1.44e-1)" "unprognostic (2.46e-3)" "potential prognostic unfavorable (1.32e-5)" "unprognostic (1.57e-1)" "potential prognostic unfavorable (1.56e-4)" "unprognostic (1.84e-1)" "unprognostic (7.27e-2)" "unprognostic (2.00e-2)" "unprognostic (2.99e-3)" "unprognostic (5.24e-2)" "unprognostic (2.68e-1)" "unprognostic (7.85e-3)" "unprognostic (1.23e-1)" "unprognostic (3.10e-1)" "unprognostic (2.75e-1)" "unprognostic (4.24e-2)" "unprognostic (4.77e-2)" "unprognostic (2.40e-2)" "unprognostic (2.71e-2)" "unprognostic (1.09e-1)" "unprognostic (1.71e-2)" "unprognostic (2.26e-1)" AGAP3 CENTG3 ENSG00000133612 "ArfGAP with GTPase domain, ankyrin repeat and PH domain 3" Q96P47 7 151085831-151144436 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 264.6" "Cell type enhanced" "Detected in many" "Lactotrophs: 215.1;Somatotrophs: 369.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012883 Approved NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 15 "HPA012883: " "potential prognostic favorable (2.78e-4)" "unprognostic (3.22e-2)" "unprognostic (3.19e-1)" "unprognostic (1.32e-2)" "potential prognostic unfavorable (4.82e-4)" "unprognostic (2.53e-2)" "unprognostic (2.13e-2)" "unprognostic (2.50e-2)" "unprognostic (6.66e-2)" "unprognostic (8.63e-3)" "potential prognostic unfavorable (9.15e-5)" "unprognostic (1.27e-2)" "unprognostic (9.76e-2)" "potential prognostic unfavorable (3.02e-4)" "unprognostic (1.31e-1)" "unprognostic (2.80e-3)" "unprognostic (7.68e-2)" "unprognostic (1.09e-1)" "unprognostic (3.59e-1)" "unprognostic (4.55e-2)" "unprognostic (7.77e-2)" "unprognostic (2.05e-2)" "unprognostic (8.29e-2)" "unprognostic (1.04e-2)" "unprognostic (3.56e-2)" "unprognostic (1.24e-2)" "unprognostic (4.19e-2)" "unprognostic (4.51e-1)" "unprognostic (1.46e-1)" "unprognostic (2.06e-1)" "unprognostic (9.50e-2)" AGAP4 "AGAP8, CTGLF1, CTGLF5, Em:AC012044.1, MRIP2" ENSG00000188234 "ArfGAP with GTPase domain, ankyrin repeat and PH domain 4" Q96P64 10 45825594-45853875 "Predicted intracellular proteins" "GTPase activation" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 51.9;Early spermatids: 64.8;Podocytes: 39.0;Proximal tubule cells: 51.3;Renal collecting duct intercalated cells: 32.6;Renal connecting tubule cells: 43.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" HPA042490 Uncertain NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 64: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 56: Non-specific - Sensory perception" "Cluster 105: Non-specific - Mixed function" "HPA042490: " "unprognostic (4.75e-2)" "unprognostic (7.88e-2)" "unprognostic (3.65e-1)" "unprognostic (1.74e-2)" "unprognostic (2.66e-2)" "unprognostic (3.69e-2)" "unprognostic (5.72e-2)" "unprognostic (2.41e-2)" "unprognostic (1.06e-2)" "unprognostic (1.85e-1)" "potential prognostic unfavorable (8.33e-7)" "unprognostic (1.61e-1)" "unprognostic (2.64e-1)" "potential prognostic unfavorable (3.38e-4)" "unprognostic (6.54e-2)" "unprognostic (2.36e-1)" "unprognostic (4.62e-2)" "unprognostic (4.39e-2)" "unprognostic (2.34e-1)" "unprognostic (2.54e-1)" "unprognostic (1.52e-3)" "unprognostic (2.24e-2)" "unprognostic (1.30e-2)" "unprognostic (4.94e-2)" "unprognostic (1.91e-2)" "unprognostic (3.93e-2)" "unprognostic (9.37e-2)" "unprognostic (3.26e-1)" "unprognostic (1.57e-1)" "unprognostic (2.33e-2)" AGAP5 "CTGLF2, Em:AC073389.1" ENSG00000172650 "ArfGAP with GTPase domain, ankyrin repeat and PH domain 5" A6NIR3 10 73674287-73698109 "Essential proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 12.1;Bergmann glia: 12.2;Brain excitatory neurons: 9.2;Brain inhibitory neurons: 8.9;Choroid plexus epithelial cells: 14.4;Distal convoluted tubule cells: 16.3;Ependymal cells: 11.6;Loop of henle epithelial cells: 15.4;Microglia: 19.4;Oligodendrocyte progenitor cells: 9.9;Oligodendrocytes: 10.0;Other brain neurons: 6.2;Papillary tip epithelial cells: 8.4;Podocytes: 13.7;Proximal tubule cells: 16.6;Renal collecting duct intercalated cells: 13.2;Renal collecting duct principal cells: 10.9;Renal connecting tubule cells: 13.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" HPA042490 Uncertain NA NA "Cluster 32: Basophils - Transcription" "Cluster 21: Testis - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 102: Non-specific - Mixed function" "HPA042490: " "unprognostic (5.03e-2)" "unprognostic (6.37e-2)" "unprognostic (1.84e-1)" "unprognostic (4.75e-2)" "unprognostic (1.93e-2)" "unprognostic (1.54e-2)" "unprognostic (2.33e-1)" "unprognostic (3.08e-3)" "potential prognostic unfavorable (9.66e-5)" "unprognostic (1.67e-1)" "unprognostic (2.17e-1)" "unprognostic (1.93e-1)" "unprognostic (1.21e-3)" "unprognostic (1.31e-1)" "unprognostic (2.27e-1)" "unprognostic (2.09e-1)" "unprognostic (1.46e-1)" "unprognostic (1.58e-1)" "unprognostic (1.25e-2)" "unprognostic (3.59e-3)" "unprognostic (3.18e-3)" "unprognostic (5.69e-3)" "unprognostic (4.30e-2)" "unprognostic (1.75e-1)" "unprognostic (9.39e-2)" "unprognostic (8.09e-2)" "unprognostic (2.54e-1)" "unprognostic (2.38e-3)" "unprognostic (2.22e-2)" AGAP6 "bA324H6.1, CTGLF3" ENSG00000204149 "ArfGAP with GTPase domain, ankyrin repeat and PH domain 6" Q5VW22 10 49982190-50011654 "Essential proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 13.6;Bergmann glia: 15.5;Brain excitatory neurons: 14.7;Brain inhibitory neurons: 13.4;Choroid plexus epithelial cells: 19.7;Distal convoluted tubule cells: 47.9;Loop of henle epithelial cells: 31.1;Microglia: 13.8;Oligodendrocytes: 13.9;Papillary tip epithelial cells: 25.0;Podocytes: 40.0;Proximal tubule cells: 39.8;Renal collecting duct intercalated cells: 34.3;Renal collecting duct principal cells: 27.6;Renal connecting tubule cells: 37.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 6.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" HPA042490 Uncertain NA NA "Cluster 64: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 105: Non-specific - Mixed function" "HPA042490: " "unprognostic (1.18e-1)" "unprognostic (1.65e-1)" "unprognostic (3.05e-2)" "unprognostic (1.54e-2)" "unprognostic (8.22e-2)" "potential prognostic favorable (6.83e-8)" "unprognostic (7.10e-2)" "unprognostic (2.23e-1)" "unprognostic (1.32e-1)" "unprognostic (4.66e-1)" "unprognostic (2.42e-2)" "unprognostic (1.88e-1)" "unprognostic (1.09e-2)" "unprognostic (1.45e-3)" "unprognostic (4.53e-2)" "unprognostic (2.95e-1)" "unprognostic (6.83e-3)" "unprognostic (2.60e-1)" "unprognostic (3.10e-2)" AGAP9 "bA301J7.2, CTGLF6, FLJ00312" ENSG00000204172 "ArfGAP with GTPase domain, ankyrin repeat and PH domain 9" Q5VTM2 10 47501854-47523638 "Predicted intracellular proteins" "GTPase activation" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 46.0;Early spermatids: 63.3;Loop of henle epithelial cells: 29.8;Podocytes: 41.8;Proximal tubule cells: 51.1;Renal collecting duct principal cells: 34.9;Renal connecting tubule cells: 45.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" HPA042490 Uncertain NA NA "Cluster 70: Non-specific - Protein processing" "Cluster 6: Non-specific - Immune response" "Cluster 56: Non-specific - Sensory perception" "Cluster 105: Non-specific - Mixed function" "HPA042490: " "unprognostic (4.21e-2)" "unprognostic (4.96e-2)" "unprognostic (1.71e-2)" "potential prognostic unfavorable (9.65e-5)" "unprognostic (1.64e-1)" "unprognostic (4.40e-2)" "unprognostic (3.49e-3)" "unprognostic (3.92e-1)" "potential prognostic unfavorable (1.66e-6)" "unprognostic (1.34e-1)" "unprognostic (7.44e-2)" "unprognostic (6.22e-3)" "unprognostic (8.75e-2)" "unprognostic (2.97e-2)" "unprognostic (5.32e-2)" "unprognostic (1.96e-1)" "unprognostic (4.61e-2)" "unprognostic (1.24e-1)" "unprognostic (3.96e-2)" "unprognostic (2.70e-3)" "unprognostic (7.76e-3)" "unprognostic (5.25e-3)" "unprognostic (8.50e-2)" "unprognostic (1.71e-1)" "unprognostic (1.70e-1)" "unprognostic (8.68e-2)" "unprognostic (1.98e-2)" "unprognostic (3.57e-2)" AGBL1 "CCP4, FLJ32310" ENSG00000273540 "AGBL carboxypeptidase 1" Q96MI9 15 86079871-87049169 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Corneal dystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "skeletal muscle: 7.0;tongue: 21.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 446.1;Ependymal cells: 1755.1;Gonadotrophs: 212.6;Myonuclei: 2287.5;Thymic myoid cells: 969.4" "Cell type enriched" "Detected in all" 6 "ependymal cell: 1756.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Alveolar cells type 2, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Region enriched" "Detected in some" 6 "hippocampal formation: 6.1" NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 33: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" AGBL2 "CCP2, FLJ23598" ENSG00000165923 "AGBL carboxypeptidase 2" Q5U5Z8 11 47659591-47715389 "Enzymes, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 5.1;testis: 11.4" "Cell type enriched" "Detected in some" 4 "Ependymal cells: 116.6" "Cell type enriched" "Detected in many" 4 "ependymal cell: 120.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Liver - Hepatocytes, Lung - Respiratory ciliated cells, Spleen - B-cells (Spleen), Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA007718 Uncertain Supported "Nucleoli,Basal body,Cytosol,Flagellar centriole,Mid piece,Principal piece,End piece" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 5: Rhabdoid - Unknown function" "Cluster 34: Ciliated cells - Cilia assembly & function" 1 "Nucleoli, Basal body, Cytosol, Flagellar centriole" "Mid piece, Principal piece, End piece" "HPA007718: " "unprognostic (3.83e-2)" "unprognostic (1.58e-2)" "unprognostic (2.70e-2)" "unprognostic (6.19e-3)" "unprognostic (6.26e-3)" "unprognostic (7.38e-2)" "unprognostic (1.22e-1)" AGBL3 "CCP3, MGC32955" ENSG00000146856 "AGBL carboxypeptidase 3" Q8NEM8 7 134986508-135147963 "Enzymes, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "epididymis: 7.4" "Cell type enhanced" "Detected in many" "Adipocytes: 129.0;Cardiomyocytes: 276.5;Early spermatids: 154.5;Ependymal cells: 120.1;Late primary spermatocytes: 169.9;Myonuclei: 131.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020397, HPA024150" Uncertain Approved Cytosol NA No "Cluster 24: Non-specific - Transcription" "Cluster 22: Epididymis - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" Cytosol "HPA020397: , HPA024150: " "unprognostic (5.91e-2)" "unprognostic (5.40e-2)" "unprognostic (4.78e-2)" "unprognostic (2.56e-1)" "unprognostic (2.11e-1)" "unprognostic (9.49e-2)" "unprognostic (2.76e-1)" "unprognostic (1.78e-1)" "unprognostic (1.87e-1)" "unprognostic (1.68e-1)" "unprognostic (9.10e-2)" "potential prognostic favorable (1.71e-4)" "unprognostic (2.74e-1)" "unprognostic (7.18e-2)" "unprognostic (1.53e-2)" "unprognostic (1.84e-1)" "unprognostic (1.39e-1)" AGBL4 "CCP6, FLJ14442" ENSG00000186094 "AGBL carboxypeptidase 4" Q5VU57 1 48532854-50023954 "Enzymes, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.5;choroid plexus: 3.5;retina: 4.4" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 1212.6;Choroid plexus epithelial cells: 2556.9;Cone photoreceptor cells: 2521.4;Corticotrophs: 1335.1;Endometrial ciliated cells: 1269.9;Ependymal cells: 2912.5;Gonadotrophs: 1182.2;Lactotrophs: 2467.3;Respiratory ciliated cells: 2874.0;Rod photoreceptor cells: 1201.3;Somatotrophs: 2794.1;Thyrotrophs: 3501.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037994 Approved NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 53: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" 4 "HPA037994: " "unprognostic (4.29e-1)" "unprognostic (1.06e-1)" "potential prognostic unfavorable (6.23e-4)" "unprognostic (2.21e-1)" "unprognostic (2.92e-2)" "unprognostic (3.15e-1)" "unprognostic (3.26e-2)" "unprognostic (1.03e-1)" AGBL5 "CCP5, FLJ21839" ENSG00000084693 "AGBL carboxypeptidase 5" Q8NDL9 2 27042364-27070622 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "parathyroid gland: 46.9;testis: 180.4" "Group enriched" "Detected in many" 5 "Early spermatids: 283.7;Late primary spermatocytes: 405.4;Late spermatids: 555.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells, Spleen - Endothelial cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030981 Uncertain Approved "Microtubules,Cytokinetic bridge,Primary cilium,Centriolar satellite,Basal body" Yes No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 22: Epididymis - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" "Cytokinetic bridge, Primary cilium" "Microtubules, Centriolar satellite, Basal body" "HPA030981: " "unprognostic (1.24e-1)" "unprognostic (1.66e-1)" "unprognostic (1.29e-1)" "unprognostic (1.95e-2)" "unprognostic (2.67e-2)" "unprognostic (1.27e-1)" "unprognostic (2.62e-1)" "unprognostic (7.46e-2)" "unprognostic (1.39e-1)" "potential prognostic unfavorable (2.20e-4)" "unprognostic (2.04e-3)" "unprognostic (1.85e-1)" "unprognostic (8.77e-3)" "validated prognostic unfavorable (1.13e-5)" "validated prognostic unfavorable (2.43e-6)" "unprognostic (2.24e-1)" "unprognostic (3.75e-1)" "unprognostic (4.54e-2)" "unprognostic (2.37e-1)" "unprognostic (2.72e-1)" "unprognostic (4.22e-1)" "unprognostic (2.39e-1)" "unprognostic (1.18e-1)" "unprognostic (2.46e-1)" "unprognostic (4.54e-3)" "unprognostic (5.69e-2)" "unprognostic (1.24e-1)" "unprognostic (2.51e-1)" "unprognostic (1.25e-1)" "unprognostic (2.94e-2)" "unprognostic (6.95e-2)" AGER "RAGE, SCARJ1, sRAGE" ENSG00000204305 "Advanced glycosylation end-product specific receptor" Q15109 6 32180968-32184322 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "DNA damage, DNA repair, DNA replication, Inflammatory response, Phagocytosis" "DNA-binding, Receptor, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 17 "lung: 687.2" "Cell type enriched" "Detected in many" 19 "Alveolar cells type 1: 1356.7" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 11.5" "Group enriched" "Detected in some" 11 "Lung Adenocarcinoma (TCGA): 20.0;Lung Squamous Cell Carcinoma (TCGA): 9.8;Thyroid Carcinoma (TCGA): 12.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney cancer: 2.2" "Colon - Enteric glia cells, Lung - Alveolar cells type 1" "Low region specificity" "Detected in some" "Not detected" "Not detected" "CAB011682, HPA064436, HPA069474" Enhanced Approved "Nucleoli fibrillar center,Plasma membrane,Cell Junctions" "Secreted in other tissues" Receptor NA NA 72000 "Cluster 13: Lung - Secretion" "Cluster 15: Kidney cancer - Membrane components" "Cluster 81: Alveolar cells - Lung function" 13 "Plasma membrane, Cell Junctions" "Nucleoli fibrillar center" "CAB011682: , HPA064436: , HPA069474: " "unprognostic (1.43e-1)" "unprognostic (3.52e-2)" "unprognostic (1.68e-2)" "unprognostic (7.88e-3)" "unprognostic (9.72e-2)" "unprognostic (6.00e-2)" "unprognostic (3.45e-1)" "potential prognostic favorable (8.62e-4)" "potential prognostic unfavorable (5.01e-4)" "unprognostic (9.10e-2)" "unprognostic (2.14e-1)" AGFG1 "HRB, RAB, RIP" ENSG00000173744 "ArfGAP with FG repeats 1" P52594 2 227472152-227561217 "Predicted intracellular proteins" "Differentiation, mRNA transport, Spermatogenesis, Transport" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 585.8;monocytes: 643.9;Neutrophil progenitors: 597.0;Neutrophils: 1538.4" "Cell type enhanced" "Detected in all" "endothelial cell: 736.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Macrophages, Heart muscle - Macrophages, Spleen - Neutrophils_2, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008741 Approved Supported Vesicles NA NA 45000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 10 Vesicles "HPA008741: " "unprognostic (1.78e-2)" "unprognostic (3.39e-2)" "unprognostic (1.29e-1)" "unprognostic (1.98e-3)" "unprognostic (3.80e-2)" "unprognostic (1.15e-2)" "unprognostic (1.48e-1)" "unprognostic (3.96e-1)" "unprognostic (3.97e-2)" "unprognostic (1.09e-1)" "potential prognostic favorable (5.29e-5)" "unprognostic (2.37e-1)" "unprognostic (3.09e-2)" "potential prognostic unfavorable (1.41e-8)" "unprognostic (8.04e-3)" "potential prognostic unfavorable (3.50e-5)" "unprognostic (4.94e-2)" "unprognostic (2.28e-2)" "unprognostic (2.78e-1)" "potential prognostic unfavorable (4.48e-4)" "unprognostic (7.19e-2)" "unprognostic (1.79e-2)" "unprognostic (6.70e-3)" "unprognostic (2.37e-2)" "unprognostic (1.53e-1)" "unprognostic (4.97e-2)" "unprognostic (4.18e-2)" "unprognostic (5.95e-2)" "unprognostic (3.45e-1)" "unprognostic (2.47e-1)" "unprognostic (2.02e-1)" AGFG2 "HRBL, RABR" ENSG00000106351 "ArfGAP with FG repeats 2" O95081 7 100539203-100568220 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "salivary gland: 272.4" "Cell type enhanced" "Detected in many" "Epicardial cells: 106.9;Esophageal apical cells: 195.8;Lacrimal acinar cells: 130.4;Salivary acinar cells: 175.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019689, HPA020129, HPA073562" Enhanced Approved Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 82: Salivary gland - Secretion" "Cluster 51: Neurons - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 38: Secretory epithelial cells - Exocrine secretion" Cytosol "HPA019689: , HPA020129: , HPA073562: " "unprognostic (6.16e-2)" "unprognostic (9.97e-2)" "unprognostic (7.31e-2)" "unprognostic (2.26e-1)" "unprognostic (8.05e-2)" "unprognostic (3.84e-2)" "unprognostic (6.09e-2)" "unprognostic (5.82e-2)" "unprognostic (2.32e-2)" "unprognostic (3.48e-2)" "potential prognostic favorable (5.66e-8)" "unprognostic (4.75e-2)" "unprognostic (4.74e-2)" "unprognostic (1.14e-1)" "unprognostic (1.69e-1)" "unprognostic (8.38e-2)" "unprognostic (2.63e-1)" "unprognostic (1.37e-1)" "unprognostic (5.70e-2)" "unprognostic (5.64e-2)" "unprognostic (6.10e-2)" "unprognostic (6.05e-3)" "unprognostic (1.72e-1)" "unprognostic (1.55e-1)" "unprognostic (1.56e-1)" "unprognostic (2.35e-1)" "unprognostic (9.51e-2)" "unprognostic (3.28e-1)" "unprognostic (1.27e-1)" "unprognostic (2.47e-1)" "unprognostic (1.71e-1)" AGGF1 "FLJ10283, GPATC7, GPATCH7, HSU84971, VG5Q" ENSG00000164252 "Angiogenic factor with G-patch and FHA domains 1" Q8N302 5 77029251-77065234 "Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 9.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" "Developmental protein" NA NA 270000 "Cluster 29: Non-specific - Unknown function" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 27: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 17: Non-specific - RNA processing" 16 "unprognostic (1.38e-1)" "unprognostic (4.11e-2)" "unprognostic (1.35e-1)" "unprognostic (2.01e-1)" "unprognostic (2.37e-2)" "unprognostic (2.24e-1)" "unprognostic (3.03e-1)" "unprognostic (2.07e-1)" "unprognostic (1.90e-1)" "unprognostic (1.49e-3)" "potential prognostic favorable (1.88e-7)" "unprognostic (2.06e-2)" "unprognostic (6.86e-2)" "unprognostic (1.13e-3)" "unprognostic (1.20e-1)" "unprognostic (4.87e-2)" "unprognostic (4.37e-1)" "unprognostic (1.99e-1)" "unprognostic (3.28e-2)" "unprognostic (1.20e-1)" "unprognostic (2.01e-3)" "unprognostic (7.83e-2)" "unprognostic (2.32e-1)" "unprognostic (2.69e-1)" "unprognostic (2.76e-2)" "unprognostic (1.55e-1)" "unprognostic (4.91e-2)" "unprognostic (8.38e-2)" "unprognostic (1.55e-1)" "unprognostic (2.14e-1)" "unprognostic (3.58e-1)" AGK "FLJ10842, MULK" ENSG00000006530 "Acylglycerol kinase" Q53H12 7 141551278-141655244 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" "Kinase, Transferase" "Cardiomyopathy, Cataract, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 119.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 97.6" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020959, HPA053471" Supported Supported Vesicles,Mitochondria NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 35: Non-specific - Mixed function" "Cluster 14: Neurons - Synaptic function" "Cluster 39: Non-specific - Transcription" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 29 Mitochondria Vesicles "HPA020959: , HPA053471: " "unprognostic (1.72e-1)" "unprognostic (4.08e-2)" "unprognostic (2.45e-1)" "unprognostic (1.14e-1)" "unprognostic (2.45e-2)" "unprognostic (7.21e-2)" "unprognostic (1.43e-2)" "unprognostic (2.36e-1)" "unprognostic (2.49e-1)" "potential prognostic unfavorable (1.58e-4)" "potential prognostic favorable (1.25e-4)" "unprognostic (2.72e-1)" "unprognostic (1.97e-1)" "unprognostic (1.55e-3)" "unprognostic (5.02e-2)" "unprognostic (3.66e-2)" "unprognostic (1.62e-2)" "unprognostic (5.92e-2)" "unprognostic (1.25e-1)" "unprognostic (1.55e-1)" "unprognostic (3.44e-1)" "unprognostic (4.55e-3)" "unprognostic (9.87e-2)" "potential prognostic unfavorable (2.23e-4)" "unprognostic (2.07e-1)" "unprognostic (4.36e-1)" "unprognostic (2.42e-1)" "unprognostic (7.73e-2)" "unprognostic (1.64e-1)" "unprognostic (1.31e-1)" "unprognostic (7.55e-2)" AGL GDE ENSG00000162688 "Amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase" P35573 1 99850361-99924023 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Glycogen biosynthesis" "Glycosidase, Glycosyltransferase, Hydrolase, Multifunctional enzyme, Transferase" "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "skeletal muscle: 241.2;tongue: 198.0" "Cell type enhanced" "Detected in many" "Müller glia: 239.2;Myonuclei: 1199.3;Thymic myoid cells: 654.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in all" 6 "Gallbladder cancer: 80.4" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028498, HPA054340" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 840000 "Cluster 15: NK-cells - Unknown function" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 25: Non-specific - Transcription" "Cluster 1: Neuronal - Visual perception" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 3 Nucleoplasm "Nuclear bodies, Cytosol" "HPA028498: , HPA054340: " "unprognostic (4.17e-1)" "unprognostic (1.09e-1)" "unprognostic (2.70e-3)" "unprognostic (4.79e-1)" "unprognostic (1.12e-3)" "unprognostic (1.34e-1)" "unprognostic (3.95e-2)" "unprognostic (1.45e-1)" "unprognostic (1.33e-1)" "unprognostic (4.51e-3)" "potential prognostic favorable (3.69e-7)" "unprognostic (1.07e-3)" "unprognostic (1.00e-3)" "unprognostic (1.86e-1)" "unprognostic (4.81e-2)" "unprognostic (3.46e-2)" "unprognostic (1.07e-2)" "unprognostic (2.75e-3)" "unprognostic (2.07e-2)" "unprognostic (3.03e-1)" "unprognostic (1.75e-1)" "unprognostic (1.64e-2)" "unprognostic (3.88e-1)" "unprognostic (7.04e-2)" "unprognostic (1.84e-2)" "unprognostic (2.02e-1)" "unprognostic (1.82e-2)" "unprognostic (6.90e-2)" "unprognostic (3.44e-1)" "unprognostic (4.43e-2)" "unprognostic (3.01e-3)" AGMAT FLJ23384 ENSG00000116771 Agmatinase Q9BSE5 1 15571699-15585051 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Arginine metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "kidney: 125.0;liver: 58.0;skeletal muscle: 32.1" "Cell type enhanced" "Detected in many" "Enteric stem cells: 38.2;Enteric transient amplifying cells: 41.1;Enterocytes: 41.0;Epididymal efferent duct absorptive cells: 26.2;Gastric progenitor cells: 57.7;Hepatocytes: 106.3;Paneth cells: 23.2;Proximal tubule cells: 46.0" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 9.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 4.1;T-cells: 8.4" "Cancer enhanced" "Detected in many" "liver cancer: 20.7" "Adrenal gland - Adrenal cortex cells, Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Gonadotropes, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA026443, HPA028321" Enhanced NA NA 120000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 76: Non-specific - Metabolism" "Cluster 48: Non-specific - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 88: Proximal tubular cells - Transmembrane transport" 10 "HPA026443: , HPA028321: " "unprognostic (1.18e-2)" "unprognostic (9.50e-2)" "unprognostic (3.00e-1)" "unprognostic (8.04e-3)" "unprognostic (1.77e-2)" "unprognostic (6.05e-2)" "unprognostic (1.95e-1)" "unprognostic (2.11e-1)" "unprognostic (1.03e-3)" "unprognostic (4.76e-2)" "validated prognostic favorable (5.17e-6)" "validated prognostic favorable (8.06e-5)" "unprognostic (9.33e-3)" "unprognostic (6.08e-2)" "unprognostic (2.08e-1)" "unprognostic (6.58e-3)" "unprognostic (4.98e-2)" "unprognostic (1.38e-1)" "unprognostic (3.68e-2)" "unprognostic (4.80e-2)" "unprognostic (1.82e-2)" "unprognostic (1.14e-2)" "unprognostic (4.36e-2)" "unprognostic (2.88e-1)" "unprognostic (1.24e-2)" "potential prognostic favorable (8.97e-4)" "unprognostic (4.90e-2)" "unprognostic (2.98e-2)" "unprognostic (2.39e-1)" "unprognostic (2.52e-2)" "unprognostic (2.05e-1)" AGMO "FLJ16237, TMEM195" ENSG00000187546 "Alkylglycerol monooxygenase" Q6ZNB7 7 15200317-15562015 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "liver: 114.4" "Cell type enhanced" "Detected in many" "Adipocytes: 211.9;Cholangiocytes: 117.3;Enterocytes: 191.2;Epididymal principal cells: 90.7;Fibro-adipogenic progenitors: 88.1;Hepatocytes: 345.4;Oocytes: 119.7;Papillary tip epithelial cells: 82.8;Proximal tubule cells: 204.2;Sertoli cells: 90.3;Undifferentiated spermatogonia: 366.1" "Cell type enhanced" "Detected in many" "astrocyte: 49.2;fibroblast: 46.4;oligodendrocyte: 62.6" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 31.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.4" "Lineage enriched" "Detected in single" 9 "granulocytes: 1.4" "Cancer enhanced" "Detected in many" "Rhabdoid: 11.2" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Liver - Hepatocytes, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057900 Uncertain Vesicles NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 11: White matter - Signal transduction" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 1 Vesicles "HPA057900: " "unprognostic (2.30e-2)" "unprognostic (6.11e-3)" "unprognostic (2.51e-1)" "unprognostic (2.38e-1)" "unprognostic (2.10e-2)" "potential prognostic favorable (4.69e-6)" "unprognostic (1.54e-1)" "unprognostic (3.80e-1)" "unprognostic (4.96e-2)" "unprognostic (4.18e-2)" "unprognostic (1.27e-2)" "unprognostic (1.70e-1)" "unprognostic (4.31e-2)" "unprognostic (4.81e-3)" "unprognostic (5.59e-2)" "unprognostic (3.33e-1)" "unprognostic (9.93e-2)" "unprognostic (1.00e-1)" "unprognostic (4.59e-2)" "unprognostic (3.15e-1)" AGO1 "EIF2C1, hAGO1" ENSG00000092847 "Argonaute RISC component 1" Q9UL18 1 35869808-35930532 "Predicted intracellular proteins" "RNA-mediated gene silencing, Transcription, Transcription regulation, Translation regulation" "Repressor, Ribonucleoprotein, RNA-binding" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 146.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Kidney - Fibroblasts" "Low region specificity" "Detected in all" HPA067849 Supported "Cytosol,Cytoplasmic bodies" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 61: Non-specific - Transcription" "Cluster 7: Non-specific - Ribosome" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 24: Neutrophils - Innate immunity signal integration" 52 "Cytoplasmic bodies" Cytosol "HPA067849: " "unprognostic (4.01e-2)" "unprognostic (1.39e-1)" "unprognostic (6.85e-2)" "unprognostic (4.89e-2)" "unprognostic (1.78e-1)" "unprognostic (1.49e-1)" "unprognostic (4.59e-2)" "unprognostic (6.93e-2)" "unprognostic (7.40e-3)" "validated prognostic favorable (2.04e-7)" "validated prognostic favorable (3.25e-5)" "unprognostic (3.09e-2)" "potential prognostic unfavorable (8.96e-6)" "unprognostic (1.95e-1)" "unprognostic (1.33e-1)" "unprognostic (7.41e-2)" "unprognostic (3.00e-3)" "potential prognostic unfavorable (3.22e-4)" "unprognostic (7.71e-2)" "unprognostic (1.60e-1)" "unprognostic (1.28e-1)" "unprognostic (1.69e-1)" "unprognostic (1.06e-1)" "unprognostic (5.02e-2)" "unprognostic (1.08e-1)" "unprognostic (1.41e-1)" "unprognostic (3.23e-1)" "unprognostic (3.00e-2)" "unprognostic (5.85e-2)" AGO2 "CASC7, EIF2C2, hAGO2, LINC00980, Q10" ENSG00000123908 "Argonaute RISC catalytic component 2" Q9UKV8 8 140520156-140635633 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction, RNA-mediated gene silencing, Transcription, Transcription regulation, Translation regulation" "Endonuclease, Hydrolase, Nuclease, Repressor, Ribonucleoprotein, RNA-binding" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 546.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019309, HPA067849" Approved Supported "Cytosol,Cytoplasmic bodies" NA NA 63000 "Cluster 35: Neutrophils - Protein binding" "Cluster 24: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 40: Non-specific - Unknown function" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 130 "Cytoplasmic bodies" Cytosol "CAB019309: , HPA067849: " "unprognostic (1.39e-1)" "unprognostic (3.09e-2)" "unprognostic (1.73e-2)" "unprognostic (1.57e-1)" "unprognostic (2.96e-2)" "unprognostic (1.44e-1)" "unprognostic (4.69e-3)" "unprognostic (7.47e-2)" "potential prognostic unfavorable (2.50e-4)" "unprognostic (1.19e-2)" "unprognostic (1.13e-2)" "unprognostic (4.88e-3)" "potential prognostic unfavorable (9.94e-4)" "unprognostic (1.17e-1)" "unprognostic (2.89e-2)" "unprognostic (1.75e-1)" "potential prognostic favorable (8.07e-4)" "unprognostic (1.01e-1)" "unprognostic (1.59e-1)" "unprognostic (4.06e-2)" "potential prognostic unfavorable (1.48e-4)" "unprognostic (3.41e-2)" "unprognostic (6.54e-2)" "unprognostic (6.72e-3)" "unprognostic (3.04e-1)" "unprognostic (4.04e-1)" "unprognostic (3.90e-1)" "unprognostic (4.48e-2)" "unprognostic (6.33e-2)" AGO3 "EIF2C3, FLJ12765, hAGO3" ENSG00000126070 "Argonaute RISC catalytic component 3" Q9H9G7 1 35930718-36072500 "Enzymes, Predicted intracellular proteins" "RNA-mediated gene silencing, Translation regulation" "Endonuclease, Hydrolase, Nuclease, Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Somatotrophs: 575.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048342, HPA067849, HPA075436" Uncertain Supported "Nucleoplasm,Cytosol,Cytoplasmic bodies" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 11: White matter - Signal transduction" "Cluster 37: Non-specific - mRNA processing" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 33 "Cytoplasmic bodies" "Nucleoplasm, Cytosol" "HPA048342: , HPA067849: , HPA075436: " "unprognostic (7.59e-3)" "unprognostic (1.49e-1)" "unprognostic (1.31e-2)" "unprognostic (1.36e-1)" "unprognostic (3.68e-2)" "unprognostic (3.35e-2)" "unprognostic (2.34e-3)" "unprognostic (2.47e-1)" "unprognostic (1.13e-2)" "unprognostic (6.57e-2)" "unprognostic (1.74e-2)" "unprognostic (2.24e-1)" "unprognostic (1.22e-1)" "unprognostic (8.96e-2)" "unprognostic (1.69e-1)" "unprognostic (9.19e-2)" "unprognostic (6.50e-2)" "unprognostic (2.60e-1)" "unprognostic (1.13e-1)" "unprognostic (2.75e-3)" "unprognostic (5.25e-2)" "unprognostic (5.45e-2)" "unprognostic (9.37e-3)" "unprognostic (4.81e-3)" "unprognostic (3.13e-1)" "unprognostic (3.17e-1)" "unprognostic (2.93e-2)" "unprognostic (2.13e-1)" AGO4 "EIF2C4, FLJ20033, hAGO4, KIAA1567" ENSG00000134698 "Argonaute RISC component 4" Q9HCK5 1 35808016-35857890 "Predicted intracellular proteins" "RNA-mediated gene silencing, Translation regulation" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophil progenitors: 372.1;Neutrophils: 795.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 7.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - Neutrophils_2, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "CAB012179, HPA067849" Approved Supported "Cytosol,Cytoplasmic bodies" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 40: Non-specific - Mixed function" "Cluster 55: Non-specific - Transcription" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 30 "Cytoplasmic bodies" Cytosol "CAB012179: , HPA067849: " "unprognostic (6.55e-2)" "unprognostic (3.91e-2)" "unprognostic (1.82e-1)" "unprognostic (1.23e-1)" "unprognostic (6.14e-3)" "unprognostic (1.82e-1)" "potential prognostic favorable (9.14e-4)" "potential prognostic favorable (6.20e-4)" "potential prognostic unfavorable (1.55e-6)" "unprognostic (3.94e-2)" "unprognostic (5.74e-2)" "unprognostic (3.61e-1)" "unprognostic (3.31e-3)" "unprognostic (1.23e-2)" "unprognostic (2.23e-2)" "unprognostic (1.18e-1)" "unprognostic (1.78e-2)" "unprognostic (5.45e-2)" "unprognostic (1.94e-2)" "unprognostic (4.33e-1)" "unprognostic (3.38e-2)" "unprognostic (3.79e-2)" "unprognostic (5.03e-3)" "unprognostic (1.08e-2)" "unprognostic (1.87e-1)" "unprognostic (6.99e-2)" "unprognostic (1.96e-1)" "unprognostic (5.90e-2)" "unprognostic (1.33e-1)" AGPAT1 "LPAAT-alpha, LPLAT1" ENSG00000204310 "1-acylglycerol-3-phosphate O-acyltransferase 1" Q99943 6 32168212-32178096 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 11.9;Bergmann glia: 12.4;Brain excitatory neurons: 17.8;Brain inhibitory neurons: 23.2;Ependymal cells: 20.0;Late spermatids: 10.8;Loop of henle epithelial cells: 9.1;Microglia: 9.0;Oligodendrocyte progenitor cells: 19.2;Oligodendrocytes: 21.9;Other brain neurons: 24.9;Papillary tip epithelial cells: 11.3;Platelets: 9.9;Podocytes: 9.5;Renal collecting duct principal cells: 11.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "hypothalamus: 65.3" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Skin - Sebaceous gland cells, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048478, HPA073355" Approved Supported "Endoplasmic reticulum,Rods & Rings" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 1: Neurons - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 98: Neurons - Neurotransmission & signaling" 151 "Endoplasmic reticulum" "Rods & Rings" "HPA048478: , HPA073355: " "unprognostic (3.07e-1)" "unprognostic (6.46e-2)" "unprognostic (1.31e-2)" "unprognostic (1.15e-1)" "unprognostic (9.09e-2)" "unprognostic (2.92e-2)" "unprognostic (7.43e-3)" "unprognostic (2.02e-2)" "unprognostic (1.78e-1)" "unprognostic (3.12e-1)" "potential prognostic favorable (3.14e-4)" "unprognostic (1.34e-1)" "unprognostic (5.51e-2)" "potential prognostic unfavorable (5.64e-4)" "unprognostic (1.07e-3)" "unprognostic (1.56e-1)" "unprognostic (1.10e-1)" "unprognostic (1.83e-1)" "unprognostic (1.50e-1)" "unprognostic (2.23e-1)" "unprognostic (2.76e-1)" "unprognostic (2.64e-2)" "unprognostic (4.12e-1)" "unprognostic (1.47e-1)" "unprognostic (2.21e-1)" "unprognostic (2.64e-1)" "unprognostic (2.57e-2)" "unprognostic (1.80e-1)" "unprognostic (6.29e-2)" "unprognostic (2.75e-2)" "unprognostic (6.92e-2)" AGPAT2 "BSCL, LPAAT-beta, LPLAT2" ENSG00000169692 "1-acylglycerol-3-phosphate O-acyltransferase 2" O15120 9 136673143-136687457 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Congenital generalized lipodystrophy, Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 348.8;liver: 426.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 270.8;Colonocytes: 619.9;Enterocytes: 1290.7;Esophageal apical cells: 1017.3;Late spermatids: 595.9" "Cell type enhanced" "Detected in many" "pericyte: 24.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Pituitary gland - Corticotropes, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA019544 Uncertain NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 32 "HPA019544: " "unprognostic (6.81e-2)" "unprognostic (5.77e-2)" "unprognostic (2.21e-2)" "unprognostic (3.98e-1)" "unprognostic (5.50e-2)" "unprognostic (1.02e-1)" "unprognostic (9.56e-2)" "unprognostic (2.15e-3)" "unprognostic (1.24e-2)" "unprognostic (7.60e-2)" "unprognostic (6.74e-2)" "unprognostic (1.37e-1)" "unprognostic (1.35e-1)" "unprognostic (1.61e-2)" "unprognostic (1.80e-1)" "unprognostic (3.89e-2)" "unprognostic (1.53e-1)" "potential prognostic unfavorable (5.34e-4)" "unprognostic (1.45e-1)" "unprognostic (4.04e-2)" "unprognostic (3.32e-1)" "unprognostic (2.70e-1)" "unprognostic (2.86e-1)" "unprognostic (2.36e-2)" "unprognostic (1.99e-1)" "unprognostic (2.77e-2)" "unprognostic (4.64e-1)" "unprognostic (1.81e-2)" "unprognostic (2.25e-1)" "unprognostic (4.36e-1)" "unprognostic (4.53e-2)" AGPAT3 "LPAAT-gamma, LPAAT3, LPLAT3" ENSG00000160216 "1-acylglycerol-3-phosphate O-acyltransferase 3" Q9NRZ7 21 43865223-43987592 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 314.2;Late spermatids: 292.5;Rod photoreceptor cells: 322.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 9.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Skin - Sebaceous gland cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 79: Photoreceptor cells - Phototransduction" 20 "unprognostic (7.91e-3)" "unprognostic (4.40e-3)" "unprognostic (3.28e-2)" "unprognostic (1.31e-3)" "unprognostic (6.36e-2)" "unprognostic (3.35e-1)" "unprognostic (9.48e-2)" "unprognostic (1.95e-2)" "unprognostic (1.76e-2)" "unprognostic (1.84e-1)" "potential prognostic favorable (2.42e-7)" "unprognostic (6.08e-3)" "unprognostic (1.05e-1)" "unprognostic (7.44e-2)" "unprognostic (1.38e-1)" "unprognostic (1.46e-1)" "unprognostic (1.73e-1)" "potential prognostic unfavorable (4.18e-4)" "unprognostic (4.10e-2)" "unprognostic (2.43e-2)" "unprognostic (2.25e-1)" "unprognostic (3.45e-1)" "unprognostic (1.65e-1)" "unprognostic (1.32e-1)" "unprognostic (6.10e-3)" "unprognostic (1.32e-1)" "unprognostic (2.16e-1)" "unprognostic (1.58e-1)" "unprognostic (5.94e-2)" "unprognostic (8.82e-2)" "unprognostic (1.47e-1)" AGPAT4 "dJ473J16.2, LPAAT-delta, LPAAT4, LPLAT4" ENSG00000026652 "1-acylglycerol-3-phosphate O-acyltransferase 4" Q9NRZ5 6 161129967-161274061 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 53.1" "Cell type enhanced" "Detected in many" "monocytes: 235.6;NK-cells: 213.0;Ocular epithelial cells: 186.1;Oligodendrocytes: 549.6" "Cell type enhanced" "Detected in all" "oligodendrocyte: 750.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053287, HPA060525" Approved Approved "Nucleoli,Golgi apparatus,Vesicles" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 72: Neuronal - Signal transduction" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 28 "Golgi apparatus" "Nucleoli, Vesicles" "HPA053287: , HPA060525: " "potential prognostic unfavorable (5.78e-5)" "unprognostic (4.32e-2)" "unprognostic (6.76e-2)" "unprognostic (4.28e-3)" "unprognostic (2.74e-1)" "unprognostic (1.24e-1)" "unprognostic (2.00e-1)" "unprognostic (2.02e-3)" "unprognostic (1.05e-3)" "unprognostic (2.20e-1)" "unprognostic (1.40e-1)" "unprognostic (4.05e-2)" "unprognostic (2.69e-1)" "unprognostic (1.91e-1)" "unprognostic (3.06e-1)" "unprognostic (9.06e-2)" "unprognostic (3.18e-2)" "unprognostic (3.61e-2)" "unprognostic (3.11e-1)" "unprognostic (3.72e-2)" "potential prognostic unfavorable (6.83e-4)" "unprognostic (8.62e-2)" "unprognostic (1.06e-1)" "unprognostic (2.41e-2)" "unprognostic (1.16e-3)" "unprognostic (7.87e-3)" "unprognostic (7.32e-2)" AGPAT5 "FLJ11210, LPAAT-e, LPAAT-epsilon, LPLAT5" ENSG00000155189 "1-acylglycerol-3-phosphate O-acyltransferase 5" Q9NUQ2 8 6708642-6761503 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 19.4" "Cell type enhanced" "Detected in many" "Astrocytes: 70.7;Bergmann glia: 64.2;Brain excitatory neurons: 60.5;Brain inhibitory neurons: 67.6;Ependymal cells: 155.0;Microglia: 83.0;Oligodendrocyte progenitor cells: 76.0;Oligodendrocytes: 64.3;Other brain neurons: 75.3;Proximal tubule cells: 104.3;Renal collecting duct intercalated cells: 52.2;Renal connecting tubule cells: 46.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010644, HPA010950, HPA011646" Approved Supported Mitochondria NA NA "Cluster 32: Basophils - Transcription" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 39: Astrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 102: Non-specific - Mixed function" 25 Mitochondria "HPA010644: , HPA010950: , HPA011646: " "unprognostic (1.95e-1)" "unprognostic (8.42e-3)" "unprognostic (6.43e-3)" "unprognostic (3.34e-2)" "unprognostic (6.74e-2)" "unprognostic (7.37e-2)" "unprognostic (1.16e-1)" "unprognostic (1.33e-1)" "unprognostic (9.03e-2)" "unprognostic (1.23e-1)" "potential prognostic favorable (2.18e-4)" "unprognostic (3.73e-3)" "unprognostic (3.33e-1)" "potential prognostic unfavorable (2.05e-4)" "unprognostic (3.26e-1)" "unprognostic (6.78e-2)" "unprognostic (3.50e-2)" "unprognostic (1.28e-2)" "unprognostic (2.45e-1)" "unprognostic (6.91e-2)" "unprognostic (1.35e-3)" "unprognostic (2.49e-1)" "unprognostic (2.14e-1)" "unprognostic (1.99e-1)" "unprognostic (2.38e-2)" "unprognostic (5.69e-2)" "unprognostic (2.69e-1)" "unprognostic (1.51e-1)" "unprognostic (4.96e-1)" "unprognostic (4.16e-2)" "unprognostic (1.40e-1)" AGPS "ADAP-S, ADAS, ADHAPS, ADPS, ALDHPSY" ENSG00000018510 "Alkylglycerone phosphate synthase" O00116 2 177392746-177567024 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism" Transferase "Cataract, Disease variant, Dwarfism, Rhizomelic chondrodysplasia punctata" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Breast lactating cells: 285.6;Hematopoietic stem cells: 1041.8;Neutrophil progenitors: 517.0;Thymocytes: 281.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030209, HPA030210, HPA030211" Supported Enhanced Peroxisomes NA NA 39000 "Cluster 25: Non-specific - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 30: White matter - Myelination" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 16 Peroxisomes "HPA030209: , HPA030210: , HPA030211: " "unprognostic (5.08e-1)" "unprognostic (1.81e-1)" "unprognostic (3.08e-2)" "potential prognostic unfavorable (8.91e-5)" "unprognostic (8.34e-2)" "unprognostic (6.08e-2)" "unprognostic (3.30e-2)" "unprognostic (6.26e-2)" "unprognostic (1.25e-1)" "unprognostic (2.18e-3)" "potential prognostic favorable (2.14e-7)" "unprognostic (4.26e-3)" "unprognostic (1.22e-2)" "unprognostic (1.11e-3)" "unprognostic (1.26e-3)" "unprognostic (1.18e-3)" "unprognostic (1.09e-2)" "unprognostic (2.65e-2)" "unprognostic (2.91e-1)" "unprognostic (1.21e-2)" "unprognostic (8.66e-3)" "unprognostic (1.01e-3)" "unprognostic (2.01e-1)" "unprognostic (5.63e-1)" "unprognostic (1.25e-1)" "unprognostic (2.40e-1)" "unprognostic (9.37e-3)" "unprognostic (6.85e-2)" "unprognostic (1.33e-1)" "unprognostic (3.49e-2)" "unprognostic (1.08e-1)" AGR2 "AG2, HAG-2, PDIA17, XAG-2" ENSG00000106541 "Anterior gradient 2, protein disulphide isomerase family member" O95994 7 16791811-16833433 "Predicted intracellular proteins" "Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 600.4;intestine: 1148.3;stomach 1: 1323.9" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 5149.5;Endometrial secretory cells: 2331.3;Enteric stem cells: 1534.2;Enteric transient amplifying cells: 1667.4;Fallopian tube ciliated cells: 2564.8;Foveolar cells: 3724.5;Gastric chief cells: 2238.7;Gastric progenitor cells: 5670.1;Goblet cells: 6674.9;Mucous neck cells: 2518.9;Respiratory deuterosomal cells: 2354.2;Respiratory secretory cells: 3712.2;Submucosal glandular cells: 2000.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Esophageal cancer: 605.6;Gastric cancer: 837.5" "Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA007912 Enhanced Supported "Endoplasmic reticulum" "Intracellular and membrane" "No annotated function" NA NA "Cluster 17: Intestine - Digestion" "Cluster 53: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 70: Intestinal goblet cells - Mucin production" 296 "Endoplasmic reticulum" "HPA007912: " "potential prognostic favorable (8.86e-4)" "unprognostic (1.25e-1)" "unprognostic (1.71e-1)" "unprognostic (3.68e-1)" "unprognostic (1.60e-1)" "unprognostic (9.65e-3)" "unprognostic (3.21e-3)" "potential prognostic unfavorable (4.17e-5)" "unprognostic (1.76e-2)" "unprognostic (5.19e-2)" "potential prognostic unfavorable (3.91e-5)" "unprognostic (4.70e-3)" "unprognostic (5.97e-3)" "unprognostic (4.14e-2)" "unprognostic (4.61e-1)" "unprognostic (4.01e-1)" "unprognostic (7.94e-3)" "unprognostic (6.57e-2)" "unprognostic (2.51e-1)" "unprognostic (3.88e-3)" "unprognostic (1.44e-1)" "unprognostic (1.07e-1)" "unprognostic (1.82e-2)" "unprognostic (5.40e-2)" "unprognostic (1.09e-1)" "unprognostic (2.07e-1)" "unprognostic (3.00e-1)" AGR3 "BCMP11, hAG-3, HAG3, PDIA18" ENSG00000173467 "Anterior gradient 3, protein disulphide isomerase family member" Q8TD06 7 16859412-16881987 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 211.4;intestine: 223.5;lung: 143.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 486.8;Colonocytes: 531.5;Endometrial ciliated cells: 987.3;Enteric stem cells: 499.6;Enteric transient amplifying cells: 651.9;Enterocytes: 1250.7;Epididymal efferent duct ciliated cells: 584.6;Fallopian tube ciliated cells: 1358.9;Foveolar cells: 426.3;Gastric progenitor cells: 398.6;Goblet cells: 845.8;Respiratory ciliated cells: 1172.5;Transitional alveolar cells: 887.3" "Cell type enriched" "Detected in single" 72 "ependymal cell: 23.6" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 396.0" "Region enhanced" "Detected in some" "midbrain: 7.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "breast cancer: 51.8;colorectal cancer: 65.3;Gastric cancer: 151.5" "Breast - Breast glandular cells, Colon - Colon enterocytes, Minor Salivary Gland - Minor salivary glandular cells, Stomach - Gastric mucous cells" "Region enriched" "Detected in some" 5 "olfactory bulb: 4.6" HPA053942 Enhanced Supported "Endoplasmic reticulum,Vesicles" "Intracellular and membrane" "No annotated function" NA NA 110000 "Cluster 77: Intestine - Digestion" "Cluster 46: Brainstem - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 1: Enterocytes - Absorption and Digestion" 21 "Endoplasmic reticulum" Vesicles "HPA053942: " "unprognostic (5.06e-1)" "unprognostic (1.67e-1)" "unprognostic (1.00e-1)" "unprognostic (6.85e-2)" "unprognostic (3.81e-1)" "unprognostic (1.82e-1)" "potential prognostic unfavorable (3.53e-4)" "unprognostic (1.39e-2)" "unprognostic (2.77e-2)" "unprognostic (2.61e-2)" "unprognostic (6.82e-2)" "unprognostic (1.75e-1)" "unprognostic (8.85e-2)" "unprognostic (1.02e-2)" "unprognostic (2.38e-1)" "unprognostic (1.14e-1)" "unprognostic (9.11e-2)" "unprognostic (4.69e-2)" "potential prognostic favorable (2.70e-4)" "unprognostic (1.36e-1)" "unprognostic (7.37e-2)" "unprognostic (7.36e-3)" "unprognostic (1.79e-1)" "unprognostic (2.87e-1)" "unprognostic (5.24e-2)" "unprognostic (1.68e-1)" AGRN AGRIN ENSG00000188157 Agrin O00468 1 1020120-1056118 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" Differentiation "Developmental protein" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 57.5;Loop of henle epithelial cells: 55.6;Papillary tip epithelial cells: 77.0;Podocytes: 132.7;Proximal tubule cells: 39.3;Renal collecting duct intercalated cells: 28.3;Renal collecting duct principal cells: 83.1;Renal connecting tubule cells: 59.9" "Cell type enriched" "Detected in many" 4 "pericyte: 18.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040090 Approved Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" "Developmental protein" NA NA 16000000 "Cluster 72: Kidney - Transmembrane transport" "Cluster 51: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 14 Cytosol "Plasma membrane" "HPA040090: " "unprognostic (1.69e-1)" "unprognostic (1.36e-1)" "unprognostic (3.18e-2)" "unprognostic (3.13e-3)" "unprognostic (2.82e-1)" "unprognostic (2.12e-2)" "unprognostic (7.84e-2)" "unprognostic (1.78e-1)" "unprognostic (8.01e-2)" "unprognostic (5.95e-3)" "potential prognostic favorable (4.90e-6)" "unprognostic (1.93e-1)" "unprognostic (3.88e-2)" "potential prognostic unfavorable (5.39e-4)" "unprognostic (7.11e-3)" "unprognostic (2.08e-2)" "unprognostic (4.70e-3)" "unprognostic (3.67e-2)" "unprognostic (1.54e-1)" "unprognostic (1.32e-1)" "unprognostic (5.50e-2)" "unprognostic (6.38e-3)" "unprognostic (1.86e-3)" "unprognostic (1.67e-1)" "unprognostic (9.68e-2)" "unprognostic (3.09e-1)" "unprognostic (3.82e-1)" "unprognostic (8.86e-2)" "unprognostic (1.91e-2)" "unprognostic (2.54e-1)" "unprognostic (1.68e-1)" AGRP "Agrt, ART, ASIP2" ENSG00000159723 "Agouti related neuropeptide" O00253 16 67482571-67483547 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Disease variant, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "adrenal gland: 19.9;brain: 36.4;epididymis: 35.0" "Cell type enriched" "Detected in some" 17 "Epididymal principal cells: 189.6" "Cell type enhanced" "Detected in single" "choroid plexus epithelial cell: 1.4" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in all" 30 "hypothalamus: 255.7" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in some" "Leukemia: 1.1;lymphoma: 1.3" "Lung - Macrophages" "Region enriched" "Detected in single" 16 "hypothalamus: 16.0" "Region enhanced" "Detected in single" "hypothalamus: 2.0" "HPA041017, HPA076241" Enhanced Supported Approved Vesicles "Secreted in brain" "No annotated function" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 22: Epididymis - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 35: RS4;11 - Unknown function" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" 1 Vesicles "HPA041017: , HPA076241: " "unprognostic (3.35e-2)" "unprognostic (2.00e-2)" "unprognostic (5.22e-2)" "unprognostic (1.24e-1)" AGT SERPINA8 ENSG00000135744 Angiotensinogen P01019 1 230690776-230745576 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Vasoactive, Vasoconstrictor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 1554.9" "Group enriched" "Detected in many" 6 "Cholangiocytes: 1049.7;Hepatocytes: 2176.3" "Group enriched" "Detected in many" 4 "astrocyte: 277.4;ependymal cell: 438.0" "Group enriched" "Detected in all" 9 "Glioblastoma Multiforme (TCGA): 475.9;Liver Hepatocellular Carcinoma (TCGA): 1585.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "liver cancer: 204.0" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025798 Supported "Secreted to blood" Other NA NA 5940000 40000000000 "Cluster 36: Brain & Liver - Signaling" "Cluster 44: Non-specific - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 13 "CAB025798: " "unprognostic (1.69e-1)" "unprognostic (2.49e-1)" "unprognostic (1.97e-1)" "unprognostic (1.71e-1)" "unprognostic (1.89e-2)" "unprognostic (1.17e-2)" "unprognostic (2.47e-1)" "unprognostic (2.00e-1)" "unprognostic (3.41e-2)" "unprognostic (6.64e-2)" "potential prognostic favorable (6.74e-4)" "unprognostic (8.93e-3)" "unprognostic (3.10e-1)" "unprognostic (3.89e-2)" "unprognostic (2.40e-2)" "unprognostic (2.37e-1)" "unprognostic (4.21e-2)" "unprognostic (1.37e-2)" "unprognostic (1.64e-2)" "unprognostic (3.12e-2)" "unprognostic (2.56e-2)" "unprognostic (9.36e-3)" "unprognostic (9.08e-2)" "unprognostic (1.53e-1)" "unprognostic (2.44e-1)" "unprognostic (4.94e-2)" "unprognostic (5.92e-2)" "unprognostic (5.06e-3)" "unprognostic (1.05e-1)" "unprognostic (9.54e-2)" "unprognostic (3.67e-2)" AGTPBP1 "CCP1, KIAA1035, Nna1" ENSG00000135049 "ATP/GTP binding carboxypeptidase 1" Q9UPW5 9 85546539-85742029 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 56.8;retina: 43.1" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 676.9;Endometrial ciliated cells: 494.8;Monocyte progenitors: 524.3;monocytes: 517.7;Neutrophil progenitors: 1490.7;Neutrophils: 3053.4;Oligodendrocytes: 545.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Neutrophils_2, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057208, HPA071094" Approved Supported "Nucleoplasm,Plasma membrane,Primary cilium,Centriolar satellite,Basal body" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 3 Nucleoplasm "Plasma membrane, Primary cilium, Centriolar satellite, Basal body" "HPA057208: , HPA071094: " "unprognostic (1.34e-2)" "unprognostic (3.22e-1)" "unprognostic (2.07e-2)" "unprognostic (3.72e-1)" "unprognostic (1.69e-1)" "unprognostic (9.35e-3)" "unprognostic (1.12e-1)" "unprognostic (1.73e-2)" "unprognostic (4.73e-2)" "unprognostic (1.98e-1)" "potential prognostic favorable (1.23e-4)" "unprognostic (1.00e-2)" "unprognostic (6.08e-2)" "unprognostic (1.87e-2)" "unprognostic (2.61e-1)" "unprognostic (1.22e-1)" "unprognostic (4.97e-2)" "unprognostic (1.08e-1)" "unprognostic (2.94e-3)" "unprognostic (2.77e-2)" "unprognostic (1.76e-2)" "unprognostic (4.83e-2)" "unprognostic (6.56e-2)" "unprognostic (4.10e-2)" "unprognostic (1.67e-3)" "unprognostic (1.75e-2)" "unprognostic (2.71e-1)" "unprognostic (1.98e-1)" "unprognostic (2.27e-1)" "potential prognostic unfavorable (2.14e-4)" "unprognostic (1.30e-1)" AGTR1 "AG2S, AGTR1A, AGTR1B, AT1, AT1B, AT2R1, AT2R1A, AT2R1B, HAT1R" ENSG00000144891 "Angiotensin II receptor type 1" P30556 3 148697784-148743008 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "Host-virus interaction" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 90.3;placenta: 133.2" "Cell type enhanced" "Detected in some" "Adrenal cortex cells: 61.3;Fibro-adipogenic progenitors: 177.4;Fibroblasts: 65.6;Hepatic stellate cells: 200.1;Hepatocytes: 61.3;Leydig cells: 149.2;Megakaryocyte-Erythroid progenitors: 84.1;Neuroendocrine cells: 42.9;Pericytes: 193.5" "Cell type enhanced" "Detected in some" "Bergmann glia: 25.1;pericyte: 13.7;vascular associated smooth muscle cell: 30.6" "Group enriched" "Detected in many" 8 "Breast Invasive Carcinoma (TCGA): 24.3;Kidney Renal Clear Cell Carcinoma (TCGA): 10.4;Liver Hepatocellular Carcinoma (TCGA): 19.2;Prostate Adenocarcinoma (TCGA): 14.7" "Region enriched" "Detected in many" 4 "midbrain: 17.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 9.3;Rhabdoid: 6.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA003596 Enhanced Uncertain Vesicles NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 110: Mural cells - ECM organization" 18 Vesicles "HPA003596: " "unprognostic (3.27e-1)" "unprognostic (3.10e-1)" "unprognostic (2.59e-1)" "potential prognostic unfavorable (3.98e-5)" "unprognostic (1.71e-1)" "validated prognostic favorable (7.11e-7)" "validated prognostic favorable (3.45e-4)" "unprognostic (4.30e-1)" "unprognostic (5.90e-3)" "unprognostic (9.52e-3)" "unprognostic (1.55e-2)" "unprognostic (1.40e-1)" "unprognostic (7.83e-3)" "unprognostic (3.49e-2)" "unprognostic (1.03e-1)" "unprognostic (1.18e-2)" "unprognostic (2.01e-3)" "unprognostic (3.30e-2)" "unprognostic (2.41e-1)" AGTR2 "AT2, MRX88" ENSG00000180772 "Angiotensin II receptor type 2" P50052 X 116170744-116174974 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "endometrium 1: 8.2;lung: 8.3;smooth muscle: 12.3" "Cell type enriched" "Detected in some" 4 "Alveolar cells type 2: 11.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "Lung Adenocarcinoma (TCGA): 3.6;Lung Squamous Cell Carcinoma (TCGA): 1.6;Uterine Corpus Endometrial Carcinoma (TCGA): 4.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 17 "Sarcoma: 1.6" "Low region specificity" "Detected in many" "Region enriched" "Detected in single" 9 "cerebellum: 2.6" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 81: Alveolar cells - Lung function" 4 "unprognostic (3.39e-1)" "unprognostic (5.87e-2)" "unprognostic (5.16e-2)" "unprognostic (1.33e-2)" "unprognostic (1.52e-1)" "unprognostic (2.73e-1)" AGTRAP ATRAP ENSG00000177674 "Angiotensin II receptor associated protein" Q6RW13 1 11736084-11754802 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 241.9;Monocyte progenitors: 148.1;monocytes: 156.2;Neutrophil progenitors: 136.3;Neutrophils: 320.4;Pancreatic acinar cells: 151.5" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 27.2;ependymal cell: 38.0;leukocyte: 34.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Prostate - Prostate glandular cells, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044120 Enhanced Supported "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 63 Vesicles "Golgi apparatus, Cytosol" "HPA044120: " "unprognostic (3.02e-2)" "unprognostic (8.13e-3)" "unprognostic (2.06e-1)" "unprognostic (1.97e-3)" "unprognostic (1.66e-2)" "unprognostic (1.93e-2)" "unprognostic (3.15e-2)" "unprognostic (1.74e-1)" "unprognostic (1.49e-3)" "unprognostic (4.19e-2)" "unprognostic (8.95e-2)" "unprognostic (2.07e-1)" "unprognostic (3.99e-2)" "potential prognostic unfavorable (3.18e-6)" "unprognostic (5.50e-3)" "unprognostic (2.11e-2)" "unprognostic (1.54e-1)" "unprognostic (7.81e-3)" "unprognostic (5.82e-2)" "unprognostic (6.87e-2)" "unprognostic (2.08e-1)" "unprognostic (6.85e-3)" "unprognostic (5.89e-2)" "unprognostic (6.22e-2)" "unprognostic (3.56e-3)" "unprognostic (1.24e-2)" "unprognostic (1.44e-1)" "unprognostic (8.71e-2)" "unprognostic (1.81e-1)" "unprognostic (3.21e-2)" "unprognostic (1.73e-1)" AGXT "AGT, AGT1, AGXT1, PH1, Ser-PyrAT, SPAT, SPT, TLH6" ENSG00000172482 "Alanine--glyoxylate aminotransferase" P21549 2 240868824-240880502 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Aminotransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 190 "liver: 1191.5" "Cell type enriched" "Detected in some" 52 "Hepatocytes: 2420.9" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 445 "Liver Hepatocellular Carcinoma (TCGA): 423.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 1.7;liver cancer: 1.0" "Adipose visceral - Adipocytes (Visceral), Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035370, HPA035371" Enhanced Supported Vesicles NA NA 3300000 "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 18: Liver cancer - Metabolism" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 30 Vesicles "HPA035370: , HPA035371: " "potential prognostic favorable (4.66e-5)" "unprognostic (1.52e-2)" "unprognostic (1.46e-1)" AGXT2 AGT2 ENSG00000113492 "Alanine--glyoxylate aminotransferase 2" Q9BYV1 5 34998101-35048135 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Aminotransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 43 "kidney: 194.0;liver: 115.4" "Group enriched" "Detected in some" 12 "Hepatocytes: 132.9;Proximal tubule cells: 417.4" "Cell type enhanced" "Detected in single" "thalamic excitatory: 1.5" "Group enriched" "Detected in some" 114 "Kidney Renal Clear Cell Carcinoma (TCGA): 37.8;Kidney Renal Papillary Cell Carcinoma (TCGA): 23.5;Liver Hepatocellular Carcinoma (TCGA): 19.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA037382 Enhanced NA NA 6600 "Cluster 76: Non-specific - Metabolism" "Cluster 18: Liver cancer - Metabolism" "Cluster 88: Proximal tubular cells - Transmembrane transport" "HPA037382: " "potential prognostic favorable (1.41e-8)" "unprognostic (2.70e-3)" "unprognostic (5.93e-2)" "unprognostic (7.87e-3)" "unprognostic (2.63e-3)" AHCTF1 ELYS ENSG00000153207 "AT-hook containing transcription factor 1" Q8WYP5 1 246839098-246931948 "Essential proteins, Metabolic proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, mRNA transport, Protein transport, Translocation, Transport" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 616.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 3.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031658 Uncertain Supported "Nucleoplasm,Nuclear membrane,Nuclear bodies" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 24: Neutrophils - Innate immunity signal integration" 24 "Nucleoplasm, Nuclear membrane, Nuclear bodies" "HPA031658: " "unprognostic (1.31e-2)" "unprognostic (2.12e-1)" "unprognostic (1.65e-1)" "unprognostic (9.39e-2)" "unprognostic (1.18e-1)" "unprognostic (3.68e-2)" "unprognostic (6.04e-2)" "unprognostic (1.80e-1)" "unprognostic (1.25e-1)" "unprognostic (1.76e-2)" "potential prognostic favorable (3.96e-4)" "unprognostic (6.72e-2)" "unprognostic (4.44e-3)" "unprognostic (2.96e-2)" "unprognostic (7.09e-2)" "unprognostic (1.58e-2)" "unprognostic (8.57e-3)" "unprognostic (1.00e-1)" "unprognostic (2.78e-1)" "unprognostic (1.59e-1)" "unprognostic (2.21e-1)" "unprognostic (6.76e-3)" "unprognostic (5.92e-2)" "unprognostic (2.49e-1)" "unprognostic (7.93e-3)" "unprognostic (2.57e-1)" "unprognostic (1.17e-1)" "unprognostic (1.90e-1)" "unprognostic (3.10e-1)" "unprognostic (2.71e-2)" "unprognostic (7.19e-3)" AHCY "AdoHcyase, SAHH" ENSG00000101444 Adenosylhomocysteinase P23526 20 34280268-34311802 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "One-carbon metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 89.6;Esophageal apical cells: 49.6;Goblet cells: 40.6;Late primary spermatocytes: 53.9;Tuft cells: 103.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041225, HPA044675" Approved Supported Cytosol NA NA 7200000 "Cluster 13: Non-specific - Mitochondria" "Cluster 70: Non-specific - Protein processing" "Cluster 27: Non-specific - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 65: Non-specific - Cell growth & division" 27 Cytosol "HPA041225: , HPA044675: " "unprognostic (2.14e-2)" "unprognostic (2.32e-1)" "unprognostic (3.48e-2)" "unprognostic (1.41e-1)" "unprognostic (1.08e-1)" "unprognostic (3.71e-2)" "unprognostic (1.86e-1)" "unprognostic (2.68e-2)" "unprognostic (7.18e-2)" "unprognostic (3.93e-2)" "potential prognostic favorable (1.57e-4)" "unprognostic (5.09e-2)" "unprognostic (3.55e-3)" "unprognostic (2.19e-2)" "potential prognostic unfavorable (1.93e-7)" "unprognostic (1.19e-3)" "unprognostic (3.20e-2)" "unprognostic (5.25e-2)" "unprognostic (4.31e-2)" "unprognostic (1.37e-1)" "unprognostic (5.59e-2)" "unprognostic (2.79e-2)" "unprognostic (1.36e-1)" "unprognostic (2.41e-2)" "unprognostic (7.30e-3)" "unprognostic (1.97e-3)" "unprognostic (6.62e-2)" "unprognostic (1.27e-1)" "unprognostic (8.46e-2)" "unprognostic (5.83e-2)" "unprognostic (4.88e-1)" AHCYL1 "IRBIT, PPP1R78, XPVKONA" ENSG00000168710 "Adenosylhomocysteinase like 1" O43865 1 109984765-110023742 "Predicted intracellular proteins, Transporters" "One-carbon metabolism" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 530.4;Bergmann glia: 560.5" "Cell type enhanced" "Detected in all" "astrocyte: 764.5;Bergmann glia: 637.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042589 Approved Supported Cytosol NA NA 57000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 44: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 28: Astrocytes - Homeostasis & neuron support" 53 Cytosol "HPA042589: " "unprognostic (2.12e-1)" "unprognostic (3.50e-1)" "unprognostic (2.73e-1)" "unprognostic (3.54e-1)" "potential prognostic favorable (1.85e-4)" "unprognostic (2.72e-1)" "unprognostic (1.65e-1)" "unprognostic (3.48e-1)" "unprognostic (2.27e-1)" "unprognostic (1.92e-3)" "validated prognostic favorable (4.32e-5)" "validated prognostic favorable (1.05e-4)" "unprognostic (1.08e-1)" "unprognostic (7.67e-3)" "unprognostic (1.28e-1)" "unprognostic (1.82e-1)" "unprognostic (3.30e-3)" "unprognostic (2.87e-1)" "unprognostic (3.69e-1)" "unprognostic (7.11e-2)" "unprognostic (1.53e-1)" "unprognostic (3.68e-1)" "unprognostic (1.24e-1)" "unprognostic (1.66e-1)" "unprognostic (7.05e-2)" "unprognostic (3.58e-2)" "unprognostic (1.86e-1)" "unprognostic (3.53e-1)" "unprognostic (2.51e-1)" "unprognostic (1.46e-1)" "unprognostic (2.31e-2)" AHCYL2 "ADOHCYASE3, IRBIT2, KIAA0828, long-IRBIT" ENSG00000158467 "Adenosylhomocysteinase like 2" Q96HN2 7 129225030-129430211 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "One-carbon metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 258.9;intestine: 166.5" "Cell type enhanced" "Detected in many" "Astrocytes: 700.0;Choroid plexus epithelial cells: 2725.8;Pituicytes/FSCs: 1134.1;Pituitary stem cells: 834.2;Renal collecting duct intercalated cells: 822.2;Retinal pigment epithelial cells: 848.3" "Cell type enriched" "Detected in all" 4 "choroid plexus epithelial cell: 2527.4" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 10 "choroid plexus: 1038.1" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Lung - Alveolar cells type 2, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053128 Uncertain Approved Nucleoplasm,Vesicles,Cytosol NA NA 91000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 12 Cytosol "Nucleoplasm, Vesicles" "HPA053128: " "unprognostic (1.26e-1)" "unprognostic (2.29e-1)" "unprognostic (3.31e-1)" "unprognostic (3.10e-1)" "unprognostic (3.46e-2)" "unprognostic (5.08e-3)" "unprognostic (1.53e-2)" "unprognostic (1.35e-1)" "potential prognostic favorable (9.63e-4)" "unprognostic (7.25e-2)" "validated prognostic favorable (3.57e-4)" "validated prognostic favorable (5.64e-4)" "unprognostic (1.89e-2)" "unprognostic (1.97e-1)" "unprognostic (1.41e-1)" "unprognostic (1.09e-2)" "unprognostic (9.33e-2)" "unprognostic (2.79e-2)" "unprognostic (2.54e-1)" "unprognostic (1.08e-1)" "unprognostic (8.63e-2)" "unprognostic (2.55e-1)" "unprognostic (5.50e-3)" "unprognostic (1.16e-2)" "unprognostic (7.35e-2)" "unprognostic (1.46e-1)" "unprognostic (4.13e-1)" "potential prognostic favorable (8.67e-4)" "unprognostic (4.27e-1)" "unprognostic (5.53e-2)" "unprognostic (5.13e-3)" AHDC1 "DJ159A19.3, RP1-159A19.1" ENSG00000126705 "AT-hook DNA binding motif containing 1" Q5TGY3 1 27534035-27604431 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 162.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "HPA028648, HPA028685, HPA028691" Approved Supported Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 14 Nucleoplasm "HPA028648: , HPA028685: , HPA028691: " "unprognostic (3.13e-3)" "unprognostic (1.60e-1)" "unprognostic (3.70e-1)" "unprognostic (2.75e-1)" "unprognostic (1.87e-1)" "unprognostic (1.11e-1)" "unprognostic (5.27e-1)" "unprognostic (1.33e-1)" "potential prognostic favorable (8.22e-4)" "unprognostic (3.21e-2)" "unprognostic (3.82e-3)" "unprognostic (5.13e-2)" "unprognostic (2.00e-2)" "unprognostic (2.11e-2)" "unprognostic (7.00e-3)" "unprognostic (2.42e-1)" "unprognostic (3.36e-1)" "unprognostic (1.66e-1)" "unprognostic (5.26e-2)" "unprognostic (3.19e-3)" "unprognostic (3.66e-1)" "unprognostic (1.80e-2)" "unprognostic (8.75e-2)" "unprognostic (1.48e-1)" "unprognostic (1.85e-1)" "unprognostic (3.80e-2)" "unprognostic (1.64e-1)" "unprognostic (2.82e-1)" "unprognostic (7.12e-2)" "unprognostic (2.96e-2)" "unprognostic (2.76e-1)" AHI1 "FLJ20069, JBTS3, ORF1" ENSG00000135541 "Abelson helper integration site 1" Q8N157 6 135283407-135498434 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Differentiation" "Developmental protein" "Ciliopathy, Disease variant, Joubert syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 25.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 1511.2;Corticotrophs: 1111.8;Gonadotrophs: 1277.8;Lactotrophs: 2085.0;Rod photoreceptor cells: 2047.6;Somatotrophs: 1928.7;Thyrotrophs: 2329.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031698, HPA046684" Approved Supported "Primary cilium,Centrosome" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 42: Retina - Visual perception" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 28: Non-specific - Nuclear processes" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 10 Centrosome "Primary cilium" "HPA031698: , HPA046684: " "unprognostic (4.98e-2)" "unprognostic (2.00e-3)" "unprognostic (3.49e-1)" "unprognostic (6.10e-3)" "unprognostic (7.27e-2)" "unprognostic (6.09e-2)" "unprognostic (1.02e-1)" "unprognostic (2.53e-1)" "unprognostic (1.94e-2)" "unprognostic (8.92e-3)" "unprognostic (4.52e-3)" "unprognostic (2.58e-2)" "unprognostic (1.54e-1)" "unprognostic (8.50e-2)" "unprognostic (2.53e-2)" "unprognostic (2.10e-1)" "unprognostic (2.72e-2)" "unprognostic (3.50e-1)" "unprognostic (2.40e-1)" "unprognostic (1.21e-2)" "unprognostic (1.71e-1)" "unprognostic (3.18e-3)" "unprognostic (1.92e-1)" "unprognostic (1.71e-3)" "unprognostic (5.82e-3)" "unprognostic (8.71e-2)" "unprognostic (2.54e-2)" "unprognostic (1.57e-1)" "unprognostic (1.41e-1)" "unprognostic (7.77e-2)" AHNAK "AHNAK1, MGC5395" ENSG00000124942 "AHNAK nucleoprotein" Q09666 11 62433542-62556235 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 2909.8;Esophageal suprabasal cells: 1288.7;Schwann cells: 1021.9;Suprabasal keratinocytes: 1000.4" "Cell type enhanced" "Detected in many" "endothelial cell: 159.9;fibroblast: 243.7;leukocyte: 254.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 219.0" "HPA019010, HPA019070, HPA026643" Uncertain Enhanced "Plasma membrane,Cytosol" NA NA 48000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 58: Skin - Keratinization" "Cluster 39: Astrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 45 "Plasma membrane, Cytosol" "HPA019010: , HPA019070: , HPA026643: " "unprognostic (3.17e-1)" "unprognostic (2.62e-1)" "unprognostic (2.45e-2)" "unprognostic (3.05e-2)" "unprognostic (2.43e-2)" "unprognostic (9.49e-2)" "unprognostic (3.36e-2)" "unprognostic (3.79e-2)" "unprognostic (1.37e-1)" "unprognostic (5.16e-2)" "potential prognostic favorable (4.52e-6)" "unprognostic (4.85e-3)" "unprognostic (3.53e-2)" "unprognostic (1.47e-1)" "unprognostic (5.32e-2)" "unprognostic (2.07e-2)" "unprognostic (2.20e-1)" "unprognostic (2.44e-1)" "unprognostic (1.40e-1)" "unprognostic (2.16e-2)" "unprognostic (1.89e-2)" "potential prognostic unfavorable (6.65e-4)" "unprognostic (6.09e-2)" "unprognostic (3.88e-1)" "unprognostic (4.50e-2)" "unprognostic (5.10e-3)" "unprognostic (1.15e-1)" "unprognostic (4.35e-2)" "unprognostic (4.96e-2)" "unprognostic (5.18e-2)" "unprognostic (2.01e-1)" AHNAK2 C14orf78 ENSG00000185567 "AHNAK nucleoprotein 2" Q8IVF2 14 104937244-104978374 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 294.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 146.7;Esophageal apical cells: 425.7;Esophageal basal cells: 108.3;Esophageal suprabasal cells: 298.7;Ocular epithelial cells: 114.6;Salivary duct cells: 122.6;Smooth muscle cells: 134.8;Suprabasal keratinocytes: 254.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Prostate - Smooth muscle cells, Skin - Keratinocyte (granular), Spleen - Smooth muscle cells" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 7 "medulla oblongata: 16.4;midbrain: 15.1;pons: 18.8;spinal cord: 56.8;thalamus: 21.4" "HPA000878, HPA002940, HPA004145, HPA020111" Enhanced Enhanced "Plasma membrane,Cytosol" No No 400000 "Cluster 58: Skin - Keratinization" "Cluster 45: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 3 Cytosol "Plasma membrane" "HPA000878: , HPA002940: , HPA004145: , HPA020111: " "unprognostic (3.01e-2)" "unprognostic (2.17e-1)" "unprognostic (5.53e-2)" "unprognostic (7.60e-2)" "unprognostic (6.54e-3)" "unprognostic (7.43e-2)" "potential prognostic unfavorable (2.93e-4)" "unprognostic (1.10e-2)" "unprognostic (4.88e-2)" "unprognostic (3.45e-1)" "unprognostic (5.12e-2)" "unprognostic (8.28e-2)" "unprognostic (1.76e-1)" "unprognostic (7.65e-2)" "unprognostic (8.66e-3)" "potential prognostic unfavorable (1.13e-8)" "unprognostic (4.82e-2)" "unprognostic (2.08e-1)" "unprognostic (1.48e-2)" "unprognostic (1.21e-2)" "unprognostic (5.76e-3)" "potential prognostic unfavorable (6.60e-5)" "unprognostic (8.33e-3)" "unprognostic (3.99e-2)" "unprognostic (1.02e-1)" "unprognostic (4.27e-3)" "unprognostic (3.07e-1)" "unprognostic (8.62e-3)" "unprognostic (1.39e-1)" "unprognostic (1.39e-1)" "unprognostic (3.54e-2)" AHR bHLHe76 ENSG00000106546 "Aryl hydrocarbon receptor" P35869 7 16916359-17346152 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Cell cycle, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor, Repressor" "Cancer-related genes, Disease variant, FDA approved drug targets, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epicardial cells: 170.6;Mesothelial cells: 104.4;Papillary tip epithelial cells: 224.9;Prostatic hillock cells: 67.5;Respiratory deuterosomal cells: 106.8;Respiratory secretory cells: 75.8;Retinal bipolar cells: 119.6;Urothelial cells: 93.9" "Cell type enhanced" "Detected in many" "hippocampal dentate gyrus: 46.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005072, HPA029722, HPA029723" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 30: White matter - Myelination" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 69: Urothelial cells - Basic cellular functions" 60 Cytosol Nucleoplasm "CAB005072: , HPA029722: , HPA029723: " "potential prognostic favorable (7.65e-4)" "unprognostic (1.73e-2)" "unprognostic (2.15e-1)" "unprognostic (1.24e-3)" "unprognostic (2.07e-1)" "unprognostic (2.05e-3)" "unprognostic (2.07e-2)" "unprognostic (2.98e-1)" "unprognostic (1.48e-1)" "unprognostic (3.81e-2)" "potential prognostic favorable (1.68e-6)" "unprognostic (1.34e-1)" "potential prognostic favorable (7.81e-4)" "unprognostic (1.19e-1)" "unprognostic (2.37e-1)" "unprognostic (2.47e-1)" "unprognostic (7.75e-2)" "unprognostic (2.82e-1)" "unprognostic (8.88e-2)" "unprognostic (1.72e-2)" "unprognostic (5.11e-3)" "unprognostic (2.25e-3)" "unprognostic (5.04e-2)" "unprognostic (3.12e-1)" "unprognostic (1.19e-1)" "unprognostic (1.01e-1)" "unprognostic (6.16e-2)" "unprognostic (2.11e-1)" "unprognostic (1.03e-1)" "unprognostic (1.75e-1)" "unprognostic (6.69e-2)" AHRR "AHH, AHHR, bHLHe77, KIAA1234" ENSG00000063438 "Aryl hydrocarbon receptor repressor" 5 321714-438291 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "testis: 22.8" "Group enriched" "Detected in some" 9 "Early spermatids: 142.0;Late primary spermatocytes: 168.0;Late spermatids: 93.5" "Cell type enhanced" "Detected in all" "hippocampal CA4: 63.5" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 4.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Pituitary gland - Corticotropes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA021483 Supported Nucleoplasm,Cytosol NA NA "Cluster 47: Testis - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 35: Neurons - Synaptic function & neurogenesis" 1 Nucleoplasm Cytosol "HPA021483: " "unprognostic (4.13e-2)" "unprognostic (1.63e-1)" "unprognostic (2.74e-2)" "unprognostic (4.59e-2)" "unprognostic (7.09e-2)" "potential prognostic favorable (1.51e-4)" "unprognostic (5.67e-3)" "unprognostic (3.15e-2)" "unprognostic (4.58e-3)" "unprognostic (1.02e-1)" "unprognostic (1.16e-1)" "unprognostic (7.55e-2)" "unprognostic (1.06e-2)" "unprognostic (1.23e-1)" "unprognostic (9.53e-2)" "unprognostic (7.00e-2)" AHSA1 "Aha1, C14orf3, hAha1, p38" ENSG00000100591 "Activator of HSP90 ATPase activity 1" O95433 14 77457870-77469472 "Plasma proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, Stress response" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fallopian tube ciliated cells: 241.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000903, CAB006244" Supported Supported Cytosol NA NA 110000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 75: Non-specific - Chaperones and protein folding" 67 Cytosol "CAB006244: , HPA000903: " "unprognostic (2.29e-3)" "unprognostic (4.24e-2)" "unprognostic (1.12e-3)" "unprognostic (7.06e-2)" "unprognostic (2.19e-1)" "unprognostic (9.43e-3)" "unprognostic (4.67e-2)" "unprognostic (1.68e-1)" "unprognostic (2.52e-3)" "unprognostic (3.67e-1)" "potential prognostic favorable (7.83e-4)" "unprognostic (6.99e-2)" "potential prognostic unfavorable (3.63e-5)" "validated prognostic unfavorable (5.94e-6)" "validated prognostic unfavorable (8.44e-4)" "potential prognostic unfavorable (7.75e-5)" "unprognostic (2.89e-2)" "unprognostic (3.53e-2)" "unprognostic (2.14e-1)" "unprognostic (4.64e-1)" "unprognostic (9.50e-2)" "unprognostic (1.38e-1)" "unprognostic (5.27e-3)" "unprognostic (2.20e-3)" "unprognostic (2.72e-1)" "unprognostic (4.18e-2)" "unprognostic (1.63e-1)" "unprognostic (1.99e-1)" "unprognostic (1.75e-1)" "unprognostic (1.44e-1)" "unprognostic (1.41e-1)" AHSG "A2HS, FETUA, HSGA" ENSG00000145192 "Alpha 2-HS glycoprotein" P02765 3 186613060-186621318 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Mineral balance" "Cancer-related genes, Disease variant, Hypotrichosis, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4319 "liver: 5439.8" "Cell type enriched" "Detected in some" 13 "Hepatocytes: 1253.2" "Cell type enhanced" "Detected in some" "deep-layer corticothalamic and 6b: 1.6" "Cancer enriched" "Detected in some" 211 "Liver Hepatocellular Carcinoma (TCGA): 2368.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 18 "liver cancer: 479.5" "Liver - Hepatocytes, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001524, HPA001525, CAB026209" Enhanced Enhanced "Golgi apparatus" "Secreted to blood" Other NA NA 864000000000 110000000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 18: Liver cancer - Metabolism" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 8 "Golgi apparatus" "CAB026209: , HPA001524: , HPA001525: " "unprognostic (5.35e-3)" "unprognostic (1.11e-2)" "unprognostic (2.52e-2)" "unprognostic (1.82e-1)" "unprognostic (3.38e-2)" "unprognostic (5.09e-2)" "unprognostic (5.63e-2)" AHSP "EDRF, ERAF" ENSG00000169877 "Alpha hemoglobin stabilizing protein" Q9NZD4 16 31527900-31528803 "Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 62 "bone marrow: 1571.3" "Group enriched" "Detected in some" 50 "Erythrocyte progenitors: 2430.9;Erythrocytes: 2026.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney Renal Clear Cell Carcinoma (TCGA): 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 18 "Leukemia: 33.5" "Liver - Erythroid cells, Pituitary gland - Neutrophils, Spleen - Erythrocytes, Testis - Early spermatids" "Low region specificity" "Detected in some" HPA040940 Enhanced NA NA 3300000 "Cluster 15: Bone marrow - Innate immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 12 "HPA040940: " "unprognostic (4.09e-1)" "unprognostic (4.07e-1)" "unprognostic (2.08e-2)" AICDA "AID, ARP2, CDA2, HIGM2" ENSG00000111732 "Activation induced cytidine deaminase" Q9GZX7 12 8602155-8613242 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "mRNA processing" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 10.5" "Cell type enhanced" "Detected in some" "B-cells: 1.8;Enterocytes: 2.2;Fibro-adipogenic progenitors: 2.5;Paneth cells: 3.9" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Testicular Germ Cell Tumor (TCGA): 2.0" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "naive B-cell: 2.1" "Lineage enriched" "Detected in single" 4 "B-cells: 2.1" "Cancer enriched" "Detected in some" 15 "lymphoma: 25.6" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 11: White matter - Signal transduction" "Cluster 55: Lymphoma - Immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 22 "unprognostic (2.31e-1)" "unprognostic (3.14e-3)" "unprognostic (1.02e-1)" AIDA "C1orf80, FLJ12806" ENSG00000186063 "Axin interactor, dorsalization associated" Q96BJ3 1 222668013-222713210 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglia: 67.8" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 86.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027935 Approved Approved "Microtubules,Cytokinetic bridge,Primary cilium,Basal body" Yes No "Cluster 14: Non-specific - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 9 "Microtubules, Primary cilium" "Cytokinetic bridge, Basal body" "HPA027935: " "unprognostic (8.68e-3)" "unprognostic (1.61e-1)" "unprognostic (1.28e-1)" "unprognostic (1.47e-2)" "unprognostic (1.00e-1)" "unprognostic (1.54e-2)" "unprognostic (1.02e-1)" "unprognostic (5.13e-2)" "unprognostic (1.36e-2)" "unprognostic (2.09e-1)" "potential prognostic favorable (7.46e-5)" "unprognostic (7.30e-2)" "potential prognostic unfavorable (1.62e-5)" "unprognostic (1.74e-2)" "unprognostic (1.57e-1)" "unprognostic (1.05e-2)" "unprognostic (3.48e-2)" "unprognostic (1.63e-1)" "unprognostic (2.85e-2)" "unprognostic (6.24e-2)" "unprognostic (7.86e-3)" "unprognostic (1.81e-2)" "unprognostic (9.33e-2)" "unprognostic (1.45e-1)" "unprognostic (1.05e-1)" "unprognostic (1.94e-1)" "unprognostic (4.76e-2)" "unprognostic (8.39e-2)" "unprognostic (2.64e-1)" "unprognostic (1.27e-2)" "unprognostic (3.80e-2)" AIF1 "AIF-1, Em:AF129756.17, IBA1, IRT-1" ENSG00000204472 "Allograft inflammatory factor 1" P55008 6 31615217-31617021 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 221.5;lymphoid tissue: 358.4" "Group enriched" "Detected in many" 5 "cDC: 903.3;Hofbauer cells: 2382.5;Kupffer cells: 2212.8;Macrophages: 840.9;monocytes: 1380.8;Neutrophils: 700.6" "Group enriched" "Detected in some" 17 "central nervous system macrophage: 129.5;leukocyte: 35.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 26 "classical monocyte: 3836.5;intermediate monocyte: 6563.8;myeloid DC: 2046.7;neutrophil: 2962.5;non-classical monocyte: 7784.5" "Group enriched" "Detected in all" 74 "dendritic cells: 2046.7;granulocytes: 2962.5;monocytes: 7784.5" "Cancer enriched" "Detected in some" 28 "Leukemia: 86.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Podocytes, Liver - Kupffer cells, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Spleen - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049234, HPA062949" Enhanced Uncertain Cytosol NA NA 56000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 3 Cytosol "HPA049234: , HPA062949: " "unprognostic (1.02e-1)" "unprognostic (1.84e-2)" "unprognostic (1.15e-1)" "potential prognostic favorable (6.65e-4)" "unprognostic (5.90e-2)" "unprognostic (2.65e-1)" "unprognostic (2.30e-1)" "unprognostic (9.85e-2)" "unprognostic (1.87e-1)" "unprognostic (2.41e-1)" "unprognostic (2.08e-2)" "unprognostic (4.61e-1)" "unprognostic (1.39e-1)" "unprognostic (5.58e-2)" "unprognostic (2.86e-1)" "unprognostic (1.10e-2)" "unprognostic (3.72e-3)" "unprognostic (1.03e-2)" "unprognostic (1.07e-1)" "unprognostic (1.88e-1)" "unprognostic (2.73e-1)" "unprognostic (2.20e-1)" "unprognostic (1.03e-1)" "unprognostic (7.93e-2)" "unprognostic (8.45e-2)" "unprognostic (1.43e-2)" "unprognostic (3.97e-2)" "unprognostic (8.51e-2)" "potential prognostic unfavorable (4.53e-4)" "unprognostic (8.34e-2)" "unprognostic (6.83e-2)" AIF1L "C9orf58, FLJ12783, IBA2" ENSG00000126878 "Allograft inflammatory factor 1 like" Q9BQI0 9 131096476-131123152 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 262.3;kidney: 358.0;lymphoid tissue: 194.9" "Cell type enriched" "Detected in many" 5 "Esophageal apical cells: 2987.9" "Cell type enhanced" "Detected in many" "Bergmann glia: 51.8;endothelial cell: 139.2;oligodendrocyte: 77.2" "Cancer enhanced" "Detected in all" "Kidney Renal Papillary Cell Carcinoma (TCGA): 200.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Endothelial cells, Prostate - Endothelial cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020522, HPA056852" Enhanced NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 6: Non-specific - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 84: Apical squamous epithelium - Cornification" 19 "HPA020522: , HPA056852: " "unprognostic (8.46e-3)" "unprognostic (2.16e-2)" "unprognostic (6.01e-2)" "unprognostic (2.05e-1)" "unprognostic (2.15e-2)" "unprognostic (1.29e-1)" "unprognostic (1.54e-2)" "unprognostic (3.87e-2)" "unprognostic (1.06e-1)" "unprognostic (2.86e-2)" "potential prognostic favorable (6.10e-5)" "unprognostic (6.06e-3)" "potential prognostic favorable (6.02e-6)" "unprognostic (1.51e-2)" "unprognostic (3.94e-3)" "unprognostic (7.12e-2)" "unprognostic (2.34e-2)" "unprognostic (2.85e-1)" "unprognostic (3.38e-3)" "unprognostic (1.51e-1)" "unprognostic (4.03e-1)" "unprognostic (1.08e-1)" "unprognostic (7.76e-2)" "unprognostic (2.88e-1)" "unprognostic (3.34e-1)" "unprognostic (1.13e-1)" "unprognostic (9.45e-3)" "unprognostic (3.53e-1)" "unprognostic (1.70e-1)" "unprognostic (7.89e-3)" "unprognostic (3.00e-2)" AIFM1 "AIF, AUNX1, CMTX4, DFNX5, NAMSD, PDCD8" ENSG00000156709 "Apoptosis inducing factor mitochondria associated 1" O95831 X 130124666-130165879 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "DNA-binding, Oxidoreductase" "Charcot-Marie-Tooth disease, Deafness, Disease variant, Dwarfism, Intellectual disability, Neurodegeneration, Neuropathy, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 111.9;Oocytes: 133.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Pancreas - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003764, HPA030611" Enhanced Supported "Mitochondria,Connecting piece" NA NA 240000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 36: Non-specific - mRNA processing" "Cluster 97: Non-specific - Cellular respiration" 150 Mitochondria "Connecting piece" "CAB003764: , HPA030611: " "unprognostic (1.05e-1)" "unprognostic (1.48e-3)" "unprognostic (1.07e-1)" "unprognostic (8.01e-2)" "unprognostic (1.71e-1)" "unprognostic (3.42e-1)" "unprognostic (1.78e-1)" "unprognostic (1.64e-3)" "unprognostic (4.42e-3)" "unprognostic (9.44e-3)" "unprognostic (1.93e-3)" "unprognostic (1.65e-1)" "potential prognostic favorable (6.79e-5)" "unprognostic (3.11e-1)" "unprognostic (1.77e-1)" "unprognostic (3.90e-1)" "unprognostic (2.00e-1)" "unprognostic (9.60e-2)" "unprognostic (2.04e-1)" "unprognostic (3.74e-2)" "unprognostic (1.43e-1)" "unprognostic (6.73e-3)" "unprognostic (4.99e-3)" "unprognostic (1.34e-2)" "unprognostic (9.86e-2)" "unprognostic (3.21e-2)" "unprognostic (1.19e-1)" "unprognostic (1.12e-1)" "unprognostic (1.29e-1)" "unprognostic (6.23e-2)" "unprognostic (2.00e-2)" AIFM2 "AMID, FLJ14497, FSP1, PRG3" ENSG00000042286 "Apoptosis inducing factor mitochondria associated 2" Q9BRQ8 10 70098223-70132934 "Predicted intracellular proteins" "DNA-binding, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 191.6;Esophageal apical cells: 170.5;Late spermatids: 87.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028961, HPA042309, HPA075576" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 7: Liver cancer - Metabolism" "Cluster 89: Adipocytes - Lipid metabolism" 7 Vesicles "Plasma membrane, Cytosol" "HPA028961: , HPA042309: , HPA075576: " "unprognostic (3.96e-1)" "unprognostic (4.07e-1)" "unprognostic (1.80e-1)" "unprognostic (3.62e-2)" "unprognostic (6.15e-2)" "unprognostic (4.43e-2)" "unprognostic (6.32e-3)" "unprognostic (2.89e-2)" "unprognostic (4.83e-2)" "unprognostic (3.30e-2)" "unprognostic (5.74e-2)" "unprognostic (1.11e-1)" "unprognostic (1.00e-2)" "potential prognostic unfavorable (9.87e-4)" "unprognostic (1.88e-1)" "unprognostic (6.32e-2)" "unprognostic (7.77e-2)" "unprognostic (1.31e-1)" "unprognostic (2.02e-1)" "unprognostic (9.57e-2)" "unprognostic (8.29e-2)" "unprognostic (1.55e-1)" "unprognostic (5.88e-2)" "unprognostic (1.34e-1)" "unprognostic (9.45e-2)" "unprognostic (3.27e-3)" "unprognostic (2.05e-1)" "unprognostic (1.11e-2)" "unprognostic (2.90e-1)" "unprognostic (1.00e-2)" "unprognostic (1.28e-2)" AIFM3 "AIFL, FLJ30473" ENSG00000183773 "Apoptosis inducing factor mitochondria associated 3" Q96NN9 22 20965108-20981360 "Predicted intracellular proteins" "Apoptosis, Electron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "choroid plexus: 136.7" "Cell type enhanced" "Detected in some" "Astrocytes: 15.9;Bergmann glia: 5.2;Choroid plexus epithelial cells: 9.6;Colonocytes: 8.7;Enteric stem cells: 5.5;Enteric transient amplifying cells: 4.7;Epididymal clear cells: 4.1;Retinal pigment epithelial cells: 12.8" "Cell type enhanced" "Detected in some" "astrocyte: 15.4;choroid plexus epithelial cell: 13.1" "Group enriched" "Detected in many" 5 "Colon Adenocarcinoma (TCGA): 15.5;Rectum Adenocarcinoma (TCGA): 16.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "classical monocyte: 1.1;intermediate monocyte: 3.0;myeloid DC: 1.9;non-classical monocyte: 1.9" "Group enriched" "Detected in many" 25 "dendritic cells: 1.9;monocytes: 3.0" "Cancer enhanced" "Detected in many" "colorectal cancer: 11.4" "Adipose subcutaneous - Macrophages, Pituitary gland - Somatotropes, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001271 Supported Mitochondria NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" Mitochondria "HPA001271: " "unprognostic (4.46e-2)" "unprognostic (4.41e-3)" "unprognostic (1.66e-1)" "unprognostic (1.19e-3)" "unprognostic (1.51e-1)" "unprognostic (2.18e-1)" "unprognostic (1.01e-2)" "unprognostic (2.07e-2)" "unprognostic (1.14e-1)" "unprognostic (6.14e-2)" "unprognostic (2.03e-1)" "unprognostic (1.58e-2)" "unprognostic (5.32e-2)" "unprognostic (4.73e-3)" "unprognostic (1.07e-1)" AIG1 "AIG-1, dJ95L4.1, FLJ10485" ENSG00000146416 "Androgen induced 1" Q9NVV5 6 143060496-143341058 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 220.0" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 527.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060766 Approved Uncertain "Golgi apparatus" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 30: White matter - Myelination" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 3 "Golgi apparatus" "HPA060766: " "unprognostic (6.92e-2)" "unprognostic (1.08e-3)" "unprognostic (8.96e-3)" "potential prognostic unfavorable (1.21e-4)" "unprognostic (3.36e-2)" "unprognostic (2.79e-1)" "unprognostic (1.12e-3)" "unprognostic (6.49e-3)" "potential prognostic unfavorable (1.89e-7)" "potential prognostic unfavorable (9.38e-4)" "potential prognostic favorable (1.84e-8)" "unprognostic (3.95e-3)" "unprognostic (6.16e-2)" "unprognostic (5.24e-2)" "unprognostic (1.95e-2)" "unprognostic (1.17e-2)" "unprognostic (3.96e-2)" "unprognostic (1.14e-1)" "unprognostic (4.75e-2)" "unprognostic (1.86e-3)" "unprognostic (2.44e-2)" "unprognostic (1.12e-1)" "unprognostic (4.30e-3)" "unprognostic (3.02e-2)" "unprognostic (3.54e-2)" "unprognostic (4.84e-3)" "unprognostic (3.49e-2)" "unprognostic (3.47e-2)" "unprognostic (4.64e-2)" "unprognostic (2.79e-1)" "unprognostic (9.21e-2)" AIM2 PYHIN4 ENSG00000163568 "Absent in melanoma 2" O14862 1 159061599-159187843 "Predicted intracellular proteins" "DNA damage, Immunity, Inflammatory response, Innate immunity" DNA-binding "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 15.7;lymphoid tissue: 48.0" "Cell type enhanced" "Detected in many" "B-cells: 137.0;Choroid plexus epithelial cells: 170.8;Corticotrophs: 344.8;Gonadotrophs: 97.4;Lactotrophs: 201.3;Late spermatids: 63.3;Neutrophils: 104.0;Plasma cells: 67.6;Somatotrophs: 228.3;Thyrotrophs: 296.1;Urothelial cells: 76.9" "Cell type enriched" "Detected in many" 5 "choroid plexus epithelial cell: 153.5" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 31.9" "Region enriched" "Detected in all" 7 "choroid plexus: 19.3" "Group enriched" "Detected in many" 5 "memory B-cell: 146.1;naive B-cell: 64.9" "Lineage enriched" "Detected in many" 6 "B-cells: 146.1" "Cancer enhanced" "Detected in many" "lymphoma: 47.8;Myeloma: 24.0" "Spleen - B-cells (Spleen), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "HPA031365, HPA040309" Uncertain Supported Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 36: Choroid plexus - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 4 Mitochondria "Nucleoplasm, Cytosol" "HPA031365: , HPA040309: " "unprognostic (4.12e-2)" "unprognostic (8.24e-2)" "unprognostic (2.23e-1)" "unprognostic (2.40e-1)" "unprognostic (1.96e-1)" "unprognostic (1.43e-1)" "unprognostic (9.97e-2)" "potential prognostic favorable (9.39e-4)" "unprognostic (5.09e-1)" "potential prognostic unfavorable (1.23e-5)" "unprognostic (7.20e-2)" "unprognostic (1.29e-1)" "unprognostic (1.06e-1)" "unprognostic (2.58e-2)" "unprognostic (1.86e-1)" "unprognostic (1.33e-2)" "unprognostic (1.41e-2)" "unprognostic (8.52e-2)" "unprognostic (9.85e-3)" "unprognostic (1.05e-2)" "unprognostic (1.11e-1)" "unprognostic (2.70e-3)" "unprognostic (1.38e-1)" "unprognostic (1.38e-1)" "unprognostic (7.06e-2)" "potential prognostic unfavorable (3.63e-4)" AIMP1 "EMAP-2, EMAPII, p43, SCYE1" ENSG00000164022 "Aminoacyl tRNA synthetase complex interacting multifunctional protein 1" Q12904 4 106315544-106349456 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Apoptosis, Inflammatory response, Protein biosynthesis" "Cytokine, RNA-binding, tRNA-binding" Leukodystrophy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017618, HPA018476" Supported Enhanced Cytosol "Secreted to blood" Cytokine NA NA 6500000 31000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 51: Secretory epithelial cells - Mixed function" 45 Cytosol "CAB017618: , HPA018476: " "unprognostic (7.37e-2)" "potential prognostic unfavorable (1.48e-6)" "unprognostic (1.47e-1)" "unprognostic (1.94e-1)" "unprognostic (3.85e-2)" "unprognostic (1.82e-1)" "unprognostic (1.54e-1)" "unprognostic (1.65e-1)" "unprognostic (4.16e-3)" "potential prognostic unfavorable (1.97e-5)" "validated prognostic favorable (3.08e-4)" "validated prognostic favorable (7.70e-4)" "unprognostic (3.01e-1)" "unprognostic (1.62e-3)" "unprognostic (5.95e-2)" "unprognostic (9.45e-3)" "unprognostic (4.17e-2)" "unprognostic (2.21e-1)" "unprognostic (2.24e-1)" "unprognostic (1.87e-1)" "unprognostic (9.35e-3)" "unprognostic (7.63e-2)" "unprognostic (3.05e-3)" "unprognostic (2.58e-2)" "unprognostic (8.12e-3)" "unprognostic (2.58e-1)" "unprognostic (3.18e-2)" "unprognostic (5.76e-2)" "unprognostic (4.00e-1)" "unprognostic (1.44e-1)" "unprognostic (8.48e-2)" AIMP2 "JTV-1, JTV1, p38, PRO0992" ENSG00000106305 "Aminoacyl tRNA synthetase complex interacting multifunctional protein 2" Q13155 7 6009255-6023834 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Differentiation, Protein biosynthesis" "Developmental protein" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 151.1" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 247.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019098, HPA020057" Supported Approved Cytosol NA Yes 39000 "Cluster 33: Non-specific - ATP binding" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 104 Cytosol "HPA019098: , HPA020057: " "unprognostic (2.08e-2)" "potential prognostic unfavorable (4.46e-4)" "unprognostic (1.80e-1)" "unprognostic (7.69e-3)" "potential prognostic unfavorable (7.14e-4)" "unprognostic (7.50e-2)" "unprognostic (1.21e-1)" "unprognostic (8.60e-2)" "potential prognostic unfavorable (2.27e-4)" "potential prognostic unfavorable (7.46e-6)" "potential prognostic favorable (9.30e-5)" "unprognostic (2.89e-2)" "unprognostic (8.48e-2)" "unprognostic (6.16e-2)" "unprognostic (2.29e-3)" "unprognostic (1.38e-3)" "unprognostic (1.62e-3)" "unprognostic (1.87e-1)" "unprognostic (1.43e-1)" "unprognostic (4.80e-2)" "unprognostic (9.09e-3)" "unprognostic (6.62e-2)" "unprognostic (9.43e-2)" "unprognostic (2.38e-1)" "unprognostic (7.09e-2)" "unprognostic (3.49e-2)" "unprognostic (2.54e-1)" "unprognostic (2.16e-1)" "unprognostic (1.54e-1)" "unprognostic (5.92e-3)" "unprognostic (1.04e-2)" AIP "ARA9, FKBP16, FKBP37, XAP2" ENSG00000110711 "Aryl hydrocarbon receptor interacting protein" O00170 11 67468174-67491154 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cushing syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033674, HPA050217, CAB069477" Approved Supported Cytosol NA NA 10000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 64: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 46 Cytosol "CAB033674: , CAB069477: , HPA050217: " "unprognostic (1.08e-1)" "unprognostic (8.55e-2)" "unprognostic (2.03e-1)" "unprognostic (2.50e-1)" "unprognostic (2.55e-3)" "unprognostic (1.30e-2)" "unprognostic (1.35e-1)" "unprognostic (3.35e-2)" "unprognostic (6.48e-3)" "potential prognostic unfavorable (8.79e-4)" "unprognostic (2.38e-3)" "unprognostic (5.68e-2)" "unprognostic (1.36e-1)" "unprognostic (4.78e-3)" "unprognostic (2.26e-2)" "unprognostic (1.03e-1)" "unprognostic (2.15e-2)" "unprognostic (1.15e-1)" "unprognostic (3.31e-1)" "unprognostic (6.26e-2)" "unprognostic (5.92e-2)" "unprognostic (2.49e-1)" "unprognostic (1.89e-1)" "unprognostic (1.19e-1)" "unprognostic (1.29e-2)" "unprognostic (6.97e-2)" "unprognostic (2.11e-1)" "unprognostic (1.36e-1)" "unprognostic (1.64e-1)" "unprognostic (5.76e-2)" "unprognostic (5.46e-2)" AIPL1 LCA4 ENSG00000129221 "Aryl hydrocarbon receptor interacting protein like 1" Q9NZN9 17 6393693-6435199 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Disease variant, Leber congenital amaurosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 215 "retina: 775.1" "Cell type enriched" "Detected in some" 4 "Rod photoreceptor cells: 2243.6" "Cell type enhanced" "Detected in single" "upper rhombic lip: 1.3" "Cancer enriched" "Detected in single" 6 "Testicular Germ Cell Tumor (TCGA): 3.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 4.3;Uterine cancer: 6.6" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA026578 Enhanced Approved "Nuclear speckles,Cytosol" NA NA "Cluster 42: Retina - Visual perception" "Cluster 6: Non-specific - Immune response" "Cluster 1: Neuronal - Visual perception" "Cluster 79: Photoreceptor cells - Phototransduction" 24 "Nuclear speckles" Cytosol "HPA026578: " "unprognostic (2.13e-2)" "unprognostic (9.39e-2)" "unprognostic (9.62e-2)" AIRE "APECED, APS1, PGA1" ENSG00000160224 "Autoimmune regulator" O43918 21 44285838-44298648 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 2.0;lymphoid tissue: 1.2" "Cell type enhanced" "Detected in some" "Astrocytes: 1.1;Brain excitatory neurons: 1.8;Brain inhibitory neurons: 1.3;Epididymal efferent duct absorptive cells: 1.2;Fibroblasts: 1.3;Other brain neurons: 7.2;Peritubular myoid cells: 1.2" "Cell type enhanced" "Detected in many" "deep-layer near-projecting: 9.8;fibroblast: 15.0" "Cancer enriched" "Detected in single" 4 "Testicular Germ Cell Tumor (TCGA): 4.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 109: Neurons - Neuronal signaling" 33 "unprognostic (1.57e-1)" AJAP1 "MOT8, SHREW-1, SHREW1" ENSG00000196581 "Adherens junctions associated protein 1" Q9UKB5 1 4654609-4792534 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.0" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 53.6;Brain inhibitory neurons: 74.9;Cholangiocytes: 37.3;Choroid plexus epithelial cells: 71.1;Distal convoluted tubule cells: 41.6;Loop of henle epithelial cells: 55.6;Ocular epithelial cells: 48.1;Oligodendrocyte progenitor cells: 74.7;Oligodendrocytes: 38.5;Other brain neurons: 56.1;Proximal tubule cells: 52.7;Renal collecting duct principal cells: 30.2;Retinal bipolar cells: 55.7;Schwann cells: 34.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Kidney Renal Papillary Cell Carcinoma (TCGA): 5.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 1.8" "Lineage enhanced" "Detected in single" "granulocytes: 1.8" "Cancer enhanced" "Detected in many" "Bone cancer: 7.8" "Adrenal gland - Adrenal medulla cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 65: Brain - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 35: Neurons - Synaptic function & neurogenesis" "unprognostic (3.82e-2)" "unprognostic (1.17e-2)" "unprognostic (2.13e-1)" "validated prognostic favorable (5.70e-11)" "validated prognostic favorable (2.15e-5)" "potential prognostic favorable (4.71e-4)" "unprognostic (9.75e-2)" "unprognostic (8.22e-2)" "unprognostic (1.48e-1)" AJM1 "ajm-1, C9orf172" ENSG00000232434 "Apical junction component 1 homolog" C9J069 9 136842478-136848801 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 65.9" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 15.3;Early spermatids: 16.9;Ependymal cells: 18.2;Epididymal principal cells: 37.1;Late spermatids: 39.6;Retinal bipolar cells: 17.7;Thyrotrophs: 15.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Prostate - Smooth muscle cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021200, HPA076556" Uncertain Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 15: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" "Golgi apparatus, Plasma membrane" "HPA021200: , HPA076556: " "unprognostic (1.33e-2)" "unprognostic (1.29e-3)" "unprognostic (1.72e-1)" "unprognostic (1.95e-2)" "unprognostic (1.68e-1)" "unprognostic (5.97e-2)" "unprognostic (2.14e-2)" "unprognostic (1.83e-1)" "unprognostic (4.61e-3)" "unprognostic (7.47e-2)" "potential prognostic favorable (1.69e-4)" "unprognostic (9.39e-3)" "unprognostic (2.88e-1)" "unprognostic (5.72e-2)" "unprognostic (1.03e-1)" "unprognostic (1.87e-3)" "unprognostic (6.56e-2)" "unprognostic (3.65e-1)" "potential prognostic unfavorable (2.79e-5)" "unprognostic (8.54e-2)" "unprognostic (2.90e-3)" "unprognostic (1.31e-1)" "unprognostic (1.84e-3)" "unprognostic (2.99e-2)" AJUBA "JUB, MGC15563" ENSG00000129474 "Ajuba LIM protein" Q96IF1 14 22971177-22982551 "Cancer-related genes, Predicted intracellular proteins" "Cell adhesion, Cell cycle, RNA-mediated gene silencing, Transcription, Transcription regulation" Repressor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 58.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 2.5;Basal keratinocytes: 1.9;Choroid plexus epithelial cells: 7.1;Endometrial secretory cells: 6.2;Ependymal cells: 9.8;Late primary spermatocytes: 2.5;Tuft cells: 11.5" "Cell type enhanced" "Detected in some" "ependymal cell: 10.4;pericyte: 16.6;vascular associated smooth muscle cell: 15.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA006171 Approved Approved "Nucleoplasm,Golgi apparatus" NA Yes "Cluster 58: Skin - Keratinization" "Cluster 3: Choroid plexus - Cilium" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 22: Non-specific - Basic cellular functions" 41 "Nucleoplasm, Golgi apparatus" "HPA006171: " "unprognostic (1.07e-1)" "unprognostic (2.24e-1)" "unprognostic (4.24e-1)" "unprognostic (3.07e-1)" "unprognostic (2.21e-1)" "unprognostic (9.72e-2)" "unprognostic (1.71e-2)" "unprognostic (2.10e-1)" "unprognostic (2.04e-1)" "potential prognostic favorable (6.32e-5)" "unprognostic (4.84e-2)" "unprognostic (1.92e-1)" "potential prognostic unfavorable (3.27e-4)" "unprognostic (2.77e-2)" "unprognostic (7.18e-3)" "unprognostic (5.52e-2)" "unprognostic (1.18e-2)" "unprognostic (7.19e-2)" "unprognostic (2.05e-1)" "unprognostic (1.92e-3)" "unprognostic (3.85e-2)" "unprognostic (3.17e-1)" "unprognostic (8.54e-2)" "unprognostic (3.08e-2)" "unprognostic (1.34e-1)" "unprognostic (4.72e-1)" "unprognostic (1.81e-1)" "unprognostic (8.42e-2)" "unprognostic (6.57e-2)" AK1 ENSG00000106992 "Adenylate kinase 1" P00568 9 127866486-127877675 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 522.7;skeletal muscle: 1262.8;tongue: 730.8" "Cell type enhanced" "Detected in many" "Colonocytes: 106.0;Ependymal cells: 324.9;Epididymal efferent duct ciliated cells: 1136.1;Fallopian tube ciliated cells: 197.7" "Cell type enriched" "Detected in all" 6 "ependymal cell: 580.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Prostate - Fibroblasts, Skeletal muscle - Skeletal myocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006456, CAB009893" Enhanced Approved Cytosol,Annulus NA NA 10000000 "Cluster 25: Non-specific - Basic cellular processes" "Cluster 3: Choroid plexus - Cilium" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 34: Ciliated cells - Cilia assembly & function" 5 Cytosol Annulus "CAB009893: , HPA006456: " "potential prognostic unfavorable (3.54e-4)" "unprognostic (4.48e-2)" "unprognostic (1.72e-1)" "unprognostic (1.18e-1)" "unprognostic (6.48e-2)" "unprognostic (1.84e-1)" "unprognostic (1.32e-1)" "unprognostic (5.69e-2)" "unprognostic (2.17e-1)" "unprognostic (4.59e-2)" "unprognostic (1.01e-2)" "unprognostic (7.64e-2)" "potential prognostic favorable (1.83e-8)" "unprognostic (6.32e-3)" "unprognostic (9.58e-2)" "unprognostic (1.18e-2)" "unprognostic (4.38e-2)" "potential prognostic unfavorable (1.44e-5)" "unprognostic (1.13e-1)" "unprognostic (3.25e-3)" "unprognostic (2.02e-2)" "unprognostic (1.09e-2)" "unprognostic (1.00e-1)" "unprognostic (1.14e-1)" "unprognostic (1.28e-1)" "unprognostic (5.16e-3)" "unprognostic (1.66e-1)" "unprognostic (4.36e-3)" "unprognostic (1.14e-1)" "unprognostic (2.37e-2)" "unprognostic (1.11e-1)" AK2 ENSG00000004455 "Adenylate kinase 2" P54819 1 33007986-33080996 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Disease variant, SCID" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 271.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018479, CAB079913" Approved Approved Mitochondria NA NA 1500000 "Cluster 29: Non-specific - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 6: Non-specific - Immune response" "Cluster 37: Non-specific - mRNA processing" "Cluster 97: Non-specific - Cellular respiration" 16 Mitochondria "CAB079913: , HPA018479: " "unprognostic (2.52e-2)" "unprognostic (4.79e-2)" "unprognostic (2.42e-2)" "unprognostic (2.99e-2)" "unprognostic (6.67e-3)" "unprognostic (6.47e-2)" "unprognostic (1.03e-1)" "unprognostic (4.49e-3)" "unprognostic (5.05e-2)" "potential prognostic unfavorable (5.49e-5)" "potential prognostic favorable (8.94e-5)" "unprognostic (1.20e-2)" "unprognostic (4.79e-2)" "potential prognostic unfavorable (2.45e-6)" "unprognostic (1.57e-1)" "unprognostic (9.62e-2)" "unprognostic (1.70e-3)" "unprognostic (1.55e-1)" "unprognostic (4.63e-2)" "unprognostic (1.77e-1)" "unprognostic (2.01e-1)" "potential prognostic unfavorable (1.93e-4)" "unprognostic (1.20e-1)" "unprognostic (2.00e-2)" "unprognostic (1.26e-1)" "unprognostic (3.87e-2)" "unprognostic (1.84e-1)" "unprognostic (8.47e-2)" "unprognostic (2.63e-1)" "unprognostic (2.80e-2)" "unprognostic (5.42e-2)" AK3 "AK3L1, AK6, AKL3L1" ENSG00000147853 "Adenylate kinase 3" Q9UIJ7 9 4709556-4742043 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Ligase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 227.6" "Cell type enhanced" "Detected in all" "Distal convoluted tubule cells: 411.6;Hepatocytes: 392.2;Parietal cells: 590.5;Syncytiotrophoblasts: 420.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063324 Enhanced Supported Mitochondria NA NA 130000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 76: Non-specific - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 97: Non-specific - Cellular respiration" 12 Mitochondria "HPA063324: " "potential prognostic favorable (2.17e-4)" "unprognostic (7.18e-3)" "unprognostic (5.18e-2)" "unprognostic (6.18e-2)" "unprognostic (2.13e-1)" "unprognostic (3.71e-1)" "unprognostic (9.49e-2)" "unprognostic (1.01e-1)" "unprognostic (3.69e-2)" "unprognostic (2.04e-1)" "potential prognostic favorable (5.21e-7)" "unprognostic (3.76e-3)" "potential prognostic favorable (8.91e-4)" "unprognostic (3.51e-2)" "unprognostic (2.86e-2)" "unprognostic (1.24e-1)" "unprognostic (2.13e-1)" "unprognostic (9.16e-2)" "unprognostic (8.85e-2)" "unprognostic (4.22e-1)" "unprognostic (3.24e-2)" "unprognostic (8.28e-2)" "unprognostic (3.94e-2)" "unprognostic (2.41e-1)" "unprognostic (1.34e-2)" "unprognostic (2.40e-1)" "unprognostic (7.80e-2)" "unprognostic (1.08e-2)" "unprognostic (1.78e-1)" "unprognostic (1.67e-1)" "unprognostic (1.09e-1)" AK4 "AK3, AK3L1" ENSG00000162433 "Adenylate kinase 4" P27144 1 65147549-65232145 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 169.3;liver: 95.6" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 172.7;Hepatocytes: 275.6;Proximal tubule cells: 449.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 105.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "classical monocyte: 3.1;myeloid DC: 2.7" "Group enriched" "Detected in many" 7 "dendritic cells: 2.7;monocytes: 3.1" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Keratinocyte (other), Stomach - Chief cells" "Low region specificity" "Detected in all" "HPA042753, HPA049461" Supported Supported Mitochondria NA Yes "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 76: Non-specific - Metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 88: Proximal tubular cells - Transmembrane transport" 48 Mitochondria "HPA042753: , HPA049461: " "unprognostic (1.01e-1)" "unprognostic (1.13e-1)" "unprognostic (2.32e-2)" "unprognostic (2.34e-1)" "unprognostic (9.35e-2)" "unprognostic (6.99e-3)" "unprognostic (1.30e-3)" "potential prognostic unfavorable (9.28e-4)" "unprognostic (1.30e-3)" "potential prognostic favorable (4.86e-6)" "unprognostic (1.49e-1)" "unprognostic (7.39e-2)" "potential prognostic unfavorable (1.19e-4)" "unprognostic (5.81e-3)" "validated prognostic unfavorable (5.87e-5)" "validated prognostic unfavorable (7.45e-5)" "unprognostic (6.15e-2)" "unprognostic (2.39e-1)" "unprognostic (2.28e-1)" "unprognostic (7.15e-3)" "potential prognostic unfavorable (2.75e-5)" "unprognostic (4.22e-2)" "unprognostic (4.97e-2)" "unprognostic (3.48e-3)" "unprognostic (3.44e-1)" "unprognostic (2.30e-1)" "unprognostic (3.51e-3)" "unprognostic (4.91e-2)" "unprognostic (1.31e-1)" "unprognostic (5.10e-2)" AK4P3 "AK3L2, AK3L2P" ENSG00000233381 "Adenylate kinase 4 pseudogene 3" 12 31615023-31652095 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 1.1;placenta: 1.1" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 21.3;Cone photoreceptor cells: 124.2;Enterocytes: 31.8;Extravillous trophoblasts: 24.7;Pancreatic acinar cells: 25.0;Rod photoreceptor cells: 16.7;Sertoli cells: 21.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "HPA042753, HPA049461" Uncertain Approved Mitochondria NA NA "Cluster 76: Non-specific - Metabolism" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 79: Photoreceptor cells - Phototransduction" Mitochondria "HPA042753: , HPA049461: " AK5 ENSG00000154027 "Adenylate kinase 5" Q9Y6K8 1 77282019-77559966 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 125.0" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 371.1;Brain inhibitory neurons: 246.6;Breast hormone-responsive cells: 183.9;Breast secretory cells: 204.7;Early spermatids: 107.4;Oligodendrocyte progenitor cells: 120.2;Oligodendrocytes: 864.8;Oocytes: 142.8;Other brain neurons: 111.7;Pituicytes/FSCs: 238.8;Undifferentiated spermatogonia: 125.3" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Breast Invasive Carcinoma (TCGA): 10.0;Glioblastoma Multiforme (TCGA): 9.7;Prostate Adenocarcinoma (TCGA): 14.9;Testicular Germ Cell Tumor (TCGA): 33.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 13.6;naive CD4 T-cell: 16.4" "Group enriched" "Detected in many" 12 "dendritic cells: 13.6;T-cells: 16.4" "Cancer enhanced" "Detected in many" "Sarcoma: 52.8" "Colon - Enteric glia cells, Skeletal muscle - Fibroblasts, Testis - Spermatogonia, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019128, HPA057255" Enhanced Supported "Centriolar satellite,Cytosol" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 35: Neurons - Synaptic function & neurogenesis" Cytosol "Centriolar satellite" "HPA019128: , HPA057255: " "unprognostic (4.50e-2)" "unprognostic (1.54e-1)" "unprognostic (2.77e-2)" "unprognostic (6.79e-2)" "unprognostic (2.89e-2)" "unprognostic (1.69e-1)" "unprognostic (7.15e-2)" "unprognostic (3.62e-1)" "unprognostic (3.20e-2)" "unprognostic (6.30e-3)" "unprognostic (2.48e-1)" "unprognostic (3.48e-2)" "unprognostic (2.60e-3)" "unprognostic (3.24e-1)" "unprognostic (7.31e-2)" "unprognostic (1.61e-3)" "unprognostic (3.85e-2)" "unprognostic (8.72e-2)" "unprognostic (2.38e-1)" "unprognostic (2.11e-3)" "unprognostic (2.09e-1)" "unprognostic (5.28e-2)" "unprognostic (1.38e-1)" "unprognostic (3.40e-3)" "unprognostic (2.08e-1)" "potential prognostic unfavorable (5.55e-4)" AK6 CINAP ENSG00000085231 "Adenylate kinase 6" Q9Y3D8 5 69350984-69370013 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 8 "Early spermatids: 158.5;Late spermatids: 379.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "CAB005361, HPA070217" Supported Supported "Nuclear speckles,Centrosome" No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 5 "Nuclear speckles" Centrosome "CAB005361: , HPA070217: " "unprognostic (2.05e-1)" "unprognostic (6.11e-2)" "unprognostic (4.95e-2)" "unprognostic (2.16e-1)" "unprognostic (3.15e-3)" "unprognostic (1.65e-1)" "unprognostic (7.87e-2)" "unprognostic (1.20e-1)" "potential prognostic unfavorable (3.87e-4)" "unprognostic (5.33e-2)" "unprognostic (4.80e-2)" "unprognostic (7.16e-2)" "unprognostic (1.07e-2)" "unprognostic (2.39e-3)" "unprognostic (1.34e-1)" "unprognostic (9.20e-2)" "unprognostic (1.79e-1)" "unprognostic (9.97e-2)" "unprognostic (4.27e-3)" "unprognostic (4.97e-3)" "unprognostic (3.30e-2)" "unprognostic (1.50e-2)" "unprognostic (9.02e-2)" "unprognostic (3.62e-2)" "unprognostic (9.84e-2)" "unprognostic (1.00e-1)" "unprognostic (1.55e-1)" "unprognostic (7.01e-2)" "unprognostic (2.18e-1)" AK7 "CFAP75, FAP75, FLJ32864" ENSG00000140057 "Adenylate kinase 7" Q96M32 14 96392128-96489427 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 17.2;fallopian tube: 22.8" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 57.1;Endometrial ciliated cells: 167.3;Ependymal cells: 189.8;Epididymal efferent duct ciliated cells: 129.3;Fallopian tube ciliated cells: 216.5;Respiratory ciliated cells: 336.2" "Cell type enriched" "Detected in many" 4 "ependymal cell: 215.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 24 "basophil: 9.1" "Lineage enriched" "Detected in single" 31 "granulocytes: 9.1" "Cancer enhanced" "Detected in many" "Bone cancer: 11.6" "Adrenal gland - Adrenal cortex cells, Lung - Respiratory ciliated cells, Skin - Keratinocyte (other), Spleen - Endothelial cells, Testis - Early spermatids, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA003543 Enhanced Supported "Cytosol,Principal piece" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 107: Ciliated cells - Cilia assembly & function" "Cytosol, Principal piece" "HPA003543: " "unprognostic (1.93e-1)" "unprognostic (2.59e-2)" "unprognostic (1.39e-1)" "unprognostic (1.49e-1)" "unprognostic (6.27e-2)" "unprognostic (9.61e-2)" "unprognostic (1.73e-3)" "potential prognostic unfavorable (2.60e-5)" "unprognostic (2.48e-1)" "unprognostic (9.26e-2)" "unprognostic (1.06e-3)" "potential prognostic favorable (3.33e-4)" "unprognostic (4.93e-2)" "unprognostic (4.11e-3)" "unprognostic (8.04e-2)" "unprognostic (1.35e-1)" "unprognostic (2.40e-1)" "unprognostic (3.94e-3)" "unprognostic (1.73e-2)" "unprognostic (4.70e-2)" "unprognostic (1.51e-1)" "unprognostic (3.93e-1)" "unprognostic (2.44e-1)" "unprognostic (1.65e-2)" "unprognostic (9.02e-2)" "unprognostic (4.23e-1)" "unprognostic (1.21e-2)" "unprognostic (4.56e-2)" "unprognostic (4.12e-2)" "unprognostic (3.63e-2)" AK8 "C9orf98, FLJ32704" ENSG00000165695 "Adenylate kinase 8" Q96MA6 9 132725578-132878777 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 18.2;fallopian tube: 24.3;testis: 17.8" "Cell type enhanced" "Detected in many" "Early spermatids: 158.8;Endometrial ciliated cells: 101.4;Ependymal cells: 249.5;Epididymal principal cells: 74.4;Fallopian tube ciliated cells: 124.6;Late primary spermatocytes: 99.9;Late spermatids: 200.3;Respiratory ciliated cells: 323.5" "Cell type enriched" "Detected in many" 5 "ependymal cell: 261.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 31 "memory B-cell: 6.2;naive B-cell: 5.0;NK-cell: 3.1" "Group enriched" "Detected in many" 30 "B-cells: 6.2;NK-cells: 3.1" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells, Skin - Inner root sheath cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021443, HPA023894" Enhanced Approved "Flagellar centriole,Mid piece,Principal piece,End piece" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 22: Epididymis - Mixed function" "Cluster 3: Choroid plexus - Cilium" "Cluster 70: DU4475 - Unknown function" "Cluster 34: Ciliated cells - Cilia assembly & function" 20 "Flagellar centriole" "Mid piece, Principal piece, End piece" "HPA021443: , HPA023894: " "unprognostic (3.32e-3)" "unprognostic (3.24e-1)" "potential prognostic favorable (4.06e-4)" "unprognostic (2.83e-1)" "unprognostic (3.05e-2)" "unprognostic (1.12e-2)" "potential prognostic favorable (4.55e-8)" "unprognostic (2.04e-2)" "potential prognostic favorable (2.65e-4)" "unprognostic (3.59e-2)" "unprognostic (1.16e-1)" "unprognostic (1.50e-1)" "unprognostic (8.10e-2)" "unprognostic (5.59e-2)" "unprognostic (2.78e-1)" "unprognostic (3.12e-1)" "unprognostic (1.75e-1)" "unprognostic (3.17e-1)" "unprognostic (2.68e-2)" "unprognostic (1.36e-1)" "unprognostic (2.66e-1)" "unprognostic (1.32e-2)" AK9 "AKD1, AKD2, C6orf199, C6orf224, dJ70A9.1, FLJ25791, FLJ42177, MGC26954" ENSG00000155085 "Adenylate kinase 9" Q5TCS8 6 109492855-109691217 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Nucleotide metabolism" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 212.1;Early primary spermatocytes: 252.9;Endometrial ciliated cells: 207.6;Ependymal cells: 354.1;Fallopian tube ciliated cells: 209.9;Respiratory ciliated cells: 519.8" "Cell type enhanced" "Detected in all" "ependymal cell: 370.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Spermatocytes" "Not detected" "Not detected" "HPA030804, HPA030805, HPA031779, HPA031781, HPA036324, HPA036711" Enhanced Enhanced "Nucleoplasm,Nuclear membrane,Cytosol,Calyx" NA NA "Cluster 32: Basophils - Transcription" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" "Nucleoplasm, Nuclear membrane" "Cytosol, Calyx" "HPA030804: , HPA030805: , HPA031779: , HPA031781: , HPA036324: , HPA036711: " "unprognostic (7.67e-2)" "unprognostic (1.98e-3)" "unprognostic (1.17e-2)" "unprognostic (5.49e-2)" "potential prognostic favorable (1.08e-4)" "unprognostic (5.50e-1)" "unprognostic (1.18e-1)" "unprognostic (5.57e-2)" "unprognostic (4.37e-2)" "unprognostic (8.65e-3)" "unprognostic (5.23e-3)" "unprognostic (1.27e-1)" "potential prognostic unfavorable (9.62e-5)" "unprognostic (1.24e-2)" "unprognostic (1.39e-1)" "unprognostic (1.20e-1)" "unprognostic (1.38e-1)" "unprognostic (3.86e-1)" "unprognostic (3.18e-1)" "potential prognostic favorable (4.39e-4)" "unprognostic (1.28e-3)" "unprognostic (2.01e-1)" "unprognostic (5.17e-3)" "unprognostic (2.74e-2)" "unprognostic (1.87e-1)" "unprognostic (2.70e-1)" "unprognostic (1.39e-1)" "unprognostic (1.91e-1)" "unprognostic (1.62e-1)" AKAIN1 C18orf42 ENSG00000231824 "A-kinase anchor inhibitor 1" P0CW23 18 5142911-5197503 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 40.8" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 28.5;Brain inhibitory neurons: 5.5;Gonadotrophs: 3.2;Late primary spermatocytes: 2.8;Pancreatic islet cells: 19.2;Retinal bipolar cells: 8.1;Retinal ganglion cells: 3.9;Somatotrophs: 5.8;Undifferentiated spermatogonia: 3.1" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 54.0;hippocampal dentate gyrus: 43.4;upper rhombic lip: 67.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 2.6;Neuroblastoma: 2.9" "Adrenal gland - Adrenal medulla cells, Pancreas - Alpha cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049365 Uncertain NA NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 11: Neuronal - Sensory perception" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 1 "HPA049365: " AKAP1 "AKAP121, AKAP149, AKAP84, D-AKAP1, PPP1R43, PRKA1, S-AKAP84, SAKAP84, TDRD17" ENSG00000121057 "A-kinase anchoring protein 1" Q92667 17 57085092-57121346 "Predicted intracellular proteins, Predicted membrane proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 194.7" "Cell type enriched" "Detected in many" 5 "Late spermatids: 3774.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008620, HPA008691, CAB019286" Supported Supported Mitochondria NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 27: Breast cancer - Unknown function" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 76 Mitochondria "CAB019286: , HPA008620: , HPA008691: " "potential prognostic favorable (3.88e-4)" "unprognostic (6.76e-2)" "unprognostic (2.77e-1)" "unprognostic (2.22e-2)" "unprognostic (1.32e-1)" "unprognostic (2.25e-2)" "unprognostic (2.70e-2)" "unprognostic (1.67e-2)" "unprognostic (2.17e-2)" "unprognostic (2.54e-2)" "validated prognostic favorable (1.60e-8)" "validated prognostic favorable (1.29e-4)" "unprognostic (5.21e-2)" "unprognostic (2.52e-2)" "unprognostic (2.69e-3)" "unprognostic (1.67e-2)" "unprognostic (3.36e-2)" "unprognostic (1.53e-1)" "unprognostic (8.13e-3)" "unprognostic (1.03e-1)" "unprognostic (1.57e-1)" "unprognostic (5.78e-2)" "unprognostic (5.46e-2)" "unprognostic (8.07e-2)" "unprognostic (4.77e-3)" "potential prognostic favorable (6.47e-4)" "unprognostic (2.15e-1)" "unprognostic (6.02e-2)" "unprognostic (3.65e-1)" "unprognostic (1.52e-1)" "unprognostic (1.01e-1)" AKAP10 "D-AKAP2, MGC9414, PRKA10" ENSG00000108599 "A-kinase anchoring protein 10" O43572 17 19904302-19978343 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 252.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "testis cancer: 78.1" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028901 Approved Supported "Plasma membrane,Cytosol" Yes No "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 42: Non-specific - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" 9 "Plasma membrane, Cytosol" "HPA028901: " "unprognostic (1.28e-1)" "unprognostic (2.64e-2)" "unprognostic (2.21e-1)" "unprognostic (2.67e-2)" "unprognostic (1.35e-1)" "unprognostic (1.36e-1)" "unprognostic (3.28e-1)" "unprognostic (7.66e-2)" "unprognostic (1.60e-2)" "unprognostic (9.84e-3)" "potential prognostic favorable (1.29e-4)" "unprognostic (9.12e-3)" "unprognostic (2.39e-2)" "potential prognostic unfavorable (7.74e-4)" "unprognostic (1.79e-1)" "unprognostic (2.33e-1)" "unprognostic (1.74e-1)" "unprognostic (1.68e-1)" "unprognostic (1.82e-2)" "unprognostic (6.92e-2)" "unprognostic (2.21e-3)" "unprognostic (8.95e-2)" "potential prognostic unfavorable (2.62e-4)" "unprognostic (9.04e-2)" "unprognostic (1.13e-1)" "unprognostic (5.74e-3)" "unprognostic (2.85e-2)" "unprognostic (7.07e-2)" "unprognostic (1.43e-1)" "unprognostic (7.06e-2)" "unprognostic (2.99e-1)" AKAP11 "AKAP220, DKFZp781I12161, FLJ11304, KIAA0629, PPP1R44, PRKA11" ENSG00000023516 "A-kinase anchoring protein 11" Q9UKA4 13 42272152-42323261 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039089 Enhanced Approved "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 32: Basophils - Transcription" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 19: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 35 "Nucleoli, Plasma membrane, Cytosol" "HPA039089: " "unprognostic (9.15e-3)" "unprognostic (5.87e-2)" "unprognostic (2.20e-1)" "unprognostic (2.72e-3)" "unprognostic (1.97e-1)" "unprognostic (5.59e-2)" "unprognostic (4.06e-2)" "unprognostic (7.67e-2)" "unprognostic (6.52e-2)" "unprognostic (2.37e-2)" "potential prognostic favorable (6.82e-7)" "unprognostic (3.82e-3)" "unprognostic (4.76e-2)" "unprognostic (1.30e-1)" "unprognostic (2.78e-1)" "unprognostic (3.72e-1)" "unprognostic (5.67e-2)" "unprognostic (2.50e-1)" "unprognostic (1.05e-1)" "unprognostic (1.61e-3)" "unprognostic (1.56e-3)" "unprognostic (8.59e-2)" "unprognostic (3.60e-2)" "unprognostic (1.34e-1)" "unprognostic (1.04e-1)" "unprognostic (1.55e-1)" "unprognostic (1.54e-1)" "unprognostic (2.48e-1)" "unprognostic (5.39e-2)" "unprognostic (2.96e-2)" "unprognostic (1.22e-1)" AKAP12 "AKAP250, SSeCKS" ENSG00000131016 "A-kinase anchoring protein 12" Q02952 6 151239967-151358559 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Calmodulin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 750.0;Lymphatic endothelial cells: 1618.9;Melanocytes: 615.6;Müller glia: 1424.2;Ovarian stromal cells: 912.6;Pericytes: 619.1;Retinal ganglion cells: 571.7;Schwann cells: 958.6;Sertoli cells: 794.3;Smooth muscle cells: 885.7;Vascular endothelial cells: 657.5;Vascular smooth muscle cells: 684.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 70.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 236 "basophil: 37.3" "Lineage enriched" "Detected in single" 236 "granulocytes: 37.3" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006344, CAB026379, HPA056230" Enhanced Enhanced "Plasma membrane,Cytosol" No No 3700000 "Cluster 46: Basophils - Proteolysis" "Cluster 47: Testis - Mixed function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 72: Neuronal - Signal transduction" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 29 "Plasma membrane, Cytosol" "CAB026379: , HPA006344: , HPA056230: " "unprognostic (2.32e-1)" "unprognostic (5.50e-2)" "unprognostic (8.87e-3)" "unprognostic (2.09e-2)" "unprognostic (1.93e-2)" "unprognostic (4.09e-2)" "unprognostic (1.19e-1)" "unprognostic (1.30e-1)" "unprognostic (1.00e-1)" "unprognostic (8.12e-2)" "potential prognostic favorable (1.30e-6)" "unprognostic (1.10e-3)" "unprognostic (6.30e-2)" "unprognostic (8.48e-2)" "unprognostic (9.48e-3)" "potential prognostic unfavorable (2.30e-4)" "unprognostic (2.54e-1)" "unprognostic (8.35e-3)" "unprognostic (1.07e-1)" "potential prognostic unfavorable (9.92e-4)" "unprognostic (2.23e-2)" "unprognostic (1.57e-1)" "unprognostic (3.33e-2)" "unprognostic (5.75e-2)" "unprognostic (2.03e-1)" "unprognostic (2.14e-2)" "unprognostic (1.43e-1)" "unprognostic (4.18e-3)" "unprognostic (5.22e-1)" "unprognostic (3.54e-3)" "unprognostic (1.58e-1)" AKAP13 "AKAP-Lbc, ARHGEF13, BRX, c-lbc, HA-3, Ht31, LBC, PROTO-LB" ENSG00000170776 "A-kinase anchoring protein 13" Q12802 15 85380571-85749358 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 2273.0;Cardiomyocytes: 2979.6;Endometrial glandular cells: 3019.2;Mast cells: 2690.7;Neutrophils: 2177.6" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 1175.2;choroid plexus epithelial cell: 1186.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019773 Approved Supported Cytosol NA NA 5100 "Cluster 41: Basophils - Unknown function" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 12: Non-specific - Vasculature" "Cluster 50: Lymphoma - Unknown function" "Cluster 51: Secretory epithelial cells - Mixed function" 35 Cytosol "HPA019773: " "unprognostic (6.02e-2)" "unprognostic (1.46e-1)" "unprognostic (9.83e-3)" "unprognostic (4.18e-2)" "unprognostic (3.67e-1)" "unprognostic (2.93e-2)" "unprognostic (1.31e-1)" "unprognostic (2.00e-2)" "unprognostic (2.21e-1)" "unprognostic (1.70e-1)" "validated prognostic favorable (4.06e-5)" "validated prognostic favorable (3.37e-4)" "unprognostic (2.51e-1)" "unprognostic (4.49e-2)" "unprognostic (8.71e-2)" "unprognostic (1.59e-2)" "unprognostic (2.01e-1)" "unprognostic (7.22e-2)" "unprognostic (3.98e-3)" "unprognostic (7.92e-3)" "unprognostic (8.42e-2)" "unprognostic (6.92e-2)" "unprognostic (1.74e-1)" "unprognostic (2.19e-1)" "unprognostic (2.71e-2)" "unprognostic (3.69e-2)" "unprognostic (2.08e-1)" "unprognostic (3.04e-1)" "unprognostic (1.35e-1)" "unprognostic (7.27e-2)" "unprognostic (3.44e-1)" AKAP14 AKAP28 ENSG00000186471 "A-kinase anchoring protein 14" Q86UN6 X 119895837-119920716 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "choroid plexus: 73.0;fallopian tube: 41.4;testis: 81.5" "Cell type enriched" "Detected in some" 4 "Late spermatids: 2646.1" "Group enriched" "Detected in many" 18 "choroid plexus epithelial cell: 39.6;ependymal cell: 48.0" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 7.7" "Region enriched" "Detected in all" 5 "choroid plexus: 34.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "testis cancer: 1.4" "Lung - Respiratory ciliated cells, Pituitary gland - Thyrotropes, Testis - Late spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA060999 Enhanced NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 18: Liver cancer - Metabolism" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 14 "HPA060999: " "unprognostic (2.31e-1)" "unprognostic (5.42e-2)" "unprognostic (1.98e-1)" "unprognostic (8.48e-2)" "unprognostic (1.91e-1)" "unprognostic (1.84e-1)" "unprognostic (1.49e-1)" "unprognostic (3.30e-1)" "unprognostic (4.78e-2)" "unprognostic (2.37e-1)" "unprognostic (2.29e-1)" AKAP17A "721P, CCDC133, CXYorf3, DXYS155E, MGC39904, SFRS17A, XE7, XE7Y" ENSG00000197976 "A-kinase anchoring protein 17A" Q02040 X 1591604-1602520 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 4.5" "Lineage enriched" "Detected in single" 5 "granulocytes: 4.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043247, HPA051020" Supported Supported "Nuclear speckles,Cytosol" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 36: Non-specific - mRNA processing" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 13 "Nuclear speckles" Cytosol "HPA043247: , HPA051020: " "unprognostic (1.19e-2)" "unprognostic (1.64e-1)" "unprognostic (3.59e-2)" "unprognostic (5.97e-2)" "unprognostic (2.31e-2)" "unprognostic (1.45e-1)" "unprognostic (5.72e-3)" "unprognostic (2.23e-1)" "potential prognostic unfavorable (2.37e-4)" "unprognostic (1.16e-1)" "unprognostic (3.10e-1)" "unprognostic (1.33e-2)" "unprognostic (1.92e-1)" "unprognostic (2.78e-1)" "unprognostic (1.79e-1)" "unprognostic (6.28e-2)" "unprognostic (1.22e-1)" "unprognostic (2.50e-3)" "potential prognostic favorable (3.98e-4)" "unprognostic (1.06e-1)" "unprognostic (1.50e-3)" "unprognostic (3.09e-3)" "potential prognostic favorable (8.12e-5)" "unprognostic (4.26e-1)" "unprognostic (6.13e-2)" "unprognostic (3.28e-1)" "unprognostic (8.69e-3)" "unprognostic (1.23e-1)" AKAP3 "AKAP110, CT82, FSP95, SOB1" ENSG00000111254 "A-kinase anchoring protein 3" O75969 12 4615508-4649051 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "testis: 93.5" "Group enriched" "Detected in many" 43 "Early spermatids: 983.1;Late primary spermatocytes: 271.7;Late spermatids: 478.6" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 8.1;ependymal cell: 7.5" "Cancer enriched" "Detected in some" 7 "Testicular Germ Cell Tumor (TCGA): 12.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Brain cancer: 5.7;testis cancer: 2.5" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA039765, HPA073296" Enhanced Approved "Vesicles,Cytosol,Principal piece" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 6: Testis - Spermatogenesis" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 10 Vesicles "Cytosol, Principal piece" "HPA039765: , HPA073296: " "unprognostic (5.85e-2)" "unprognostic (5.62e-2)" "unprognostic (2.01e-1)" "unprognostic (1.26e-2)" "unprognostic (1.25e-2)" "unprognostic (8.52e-2)" "unprognostic (1.39e-1)" "unprognostic (2.10e-1)" "unprognostic (1.24e-1)" "unprognostic (3.32e-1)" "unprognostic (7.16e-2)" AKAP4 "AKAP82, CT99, Fsc1, hAKAP82, HI, p82" ENSG00000147081 "A-kinase anchoring protein 4" Q5JQC9 X 50190777-50201007 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1207 "testis: 187.4" "Cell type enriched" "Detected in some" 4 "Late spermatids: 4306.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA005949, HPA020046" Enhanced Enhanced "Principal piece" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 47: Leukemia - Hemostasis" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 2 "Principal piece" "HPA005949: , HPA020046: " AKAP5 "AKAP75, AKAP79" ENSG00000179841 "A-kinase anchoring protein 5" P24588 14 64465499-64474503 "Plasma proteins, Predicted intracellular proteins, Transporters" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 17.6" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 15.9;Brain inhibitory neurons: 29.0;Cardiomyocytes: 28.2;Goblet cells: 35.9;Mast cells: 38.7;NK-cells: 30.0;Retinal ganglion cells: 15.5" "Cell type enhanced" "Detected in all" "medium spiny neuron: 66.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "basophil: 2.9" "Lineage enriched" "Detected in single" 8 "granulocytes: 2.9" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts" "Group enriched" "Detected in all" 5 "amygdala: 27.6;basal ganglia: 79.0;cerebral cortex: 29.4;hippocampal formation: 30.8" "Group enriched" "Detected in all" 5 "amygdala: 32.3;basal ganglia: 105.6;cerebral cortex: 59.0;hippocampal formation: 57.6" "CAB004308, HPA053891, HPA070486" Enhanced Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 20 "Golgi apparatus" "Plasma membrane, Cytosol" "CAB004308: , HPA053891: , HPA070486: " "unprognostic (4.53e-2)" "unprognostic (1.63e-1)" "unprognostic (1.56e-1)" "unprognostic (4.29e-1)" "unprognostic (1.56e-2)" "potential prognostic favorable (9.13e-4)" "unprognostic (1.87e-1)" "potential prognostic favorable (4.75e-5)" "unprognostic (1.11e-1)" "unprognostic (1.28e-1)" "unprognostic (3.01e-2)" "unprognostic (8.01e-2)" "unprognostic (1.94e-1)" "unprognostic (1.81e-1)" "unprognostic (9.00e-2)" "unprognostic (4.60e-3)" "unprognostic (1.61e-3)" "unprognostic (8.62e-3)" "unprognostic (1.63e-1)" "unprognostic (2.55e-1)" AKAP6 "ADAP6, AKAP100, KIAA0311, mAKAP, PRKA6" ENSG00000151320 "A-kinase anchoring protein 6" Q13023 14 32329298-32837684 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 51.1;skeletal muscle: 44.4;tongue: 47.4" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 563.8;Bergmann glia: 936.6;Brain excitatory neurons: 609.9;Brain inhibitory neurons: 761.9;Cardiomyocytes: 1494.9;Corticotrophs: 630.5;Myonuclei: 1324.5;Oligodendrocyte progenitor cells: 582.0;Oligodendrocytes: 1258.9;Other brain neurons: 651.0;Somatotrophs: 577.9;Thymic myoid cells: 959.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "naive B-cell: 3.4" "Lineage enriched" "Detected in single" 6 "B-cells: 3.4" "Cancer enhanced" "Detected in many" "Rhabdoid: 12.8" "Adipose subcutaneous - Smooth muscle cells, Breast - Breast myoepithelial cells, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001983, HPA048741" Enhanced NA NA "Cluster 34: B-cells - Unknown function" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 5 "CAB001983: , HPA048741: " "unprognostic (6.20e-2)" "unprognostic (2.08e-1)" "unprognostic (8.26e-2)" "unprognostic (1.38e-1)" "unprognostic (3.84e-1)" "potential prognostic favorable (9.73e-6)" "unprognostic (9.52e-2)" "unprognostic (6.80e-3)" "validated prognostic favorable (2.07e-8)" "validated prognostic favorable (2.85e-4)" "unprognostic (1.43e-3)" "unprognostic (3.50e-2)" "unprognostic (1.24e-2)" "unprognostic (7.18e-2)" "unprognostic (2.30e-1)" "unprognostic (5.12e-2)" "unprognostic (5.43e-2)" "unprognostic (3.01e-2)" "unprognostic (9.55e-3)" "unprognostic (5.66e-2)" "unprognostic (1.05e-2)" "unprognostic (1.67e-2)" "unprognostic (6.47e-2)" "unprognostic (8.15e-2)" "unprognostic (1.89e-3)" "unprognostic (8.58e-2)" AKAP7 "AKAP15, AKAP18" ENSG00000118507 "A-kinase anchoring protein 7" "O43687, Q9P0M2" 6 131135467-131283535 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 54.4" "Cell type enhanced" "Detected in all" "Adrenal cortex cells: 273.3;Bergmann glia: 320.3;Cholangiocytes: 245.4;Pancreatic duct cells: 220.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Bone cancer: 27.7" "Pancreas - Ductal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027172, HPA027200, HPA028327" Approved Approved Vesicles NA NA "Cluster 11: T-cells - Unknown function" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 2: Neurons - Nucleosome" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 18: Adrenal cortex cells - Steroidogensis" 17 Vesicles "HPA027172: , HPA027200: , HPA028327: " "unprognostic (1.20e-1)" "unprognostic (5.49e-2)" "unprognostic (4.62e-1)" "unprognostic (7.80e-2)" "unprognostic (1.06e-1)" "unprognostic (1.10e-3)" "unprognostic (1.48e-2)" "unprognostic (7.80e-3)" "unprognostic (2.34e-1)" "unprognostic (1.53e-1)" "potential prognostic favorable (5.19e-4)" "unprognostic (4.03e-2)" "unprognostic (5.81e-3)" "unprognostic (4.31e-1)" "unprognostic (4.12e-2)" "unprognostic (2.11e-1)" "unprognostic (2.10e-2)" "unprognostic (2.97e-2)" "unprognostic (2.95e-2)" "unprognostic (3.13e-1)" "unprognostic (5.41e-2)" "unprognostic (3.59e-1)" "unprognostic (2.51e-3)" "unprognostic (1.12e-1)" "unprognostic (2.17e-2)" "unprognostic (9.79e-3)" "unprognostic (1.79e-1)" "unprognostic (3.52e-1)" "unprognostic (1.37e-2)" "unprognostic (4.27e-1)" "unprognostic (2.73e-1)" AKAP8 "AKAP95, DKFZp586B1222" ENSG00000105127 "A-kinase anchoring protein 8" O43823 19 15353385-15379815 "Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity, Protein transport, Transcription, Transcription regulation, Transport" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 255.5;Endometrial luminal cells: 187.9;Endometrial secretory cells: 289.7;Epididymal basal cells: 289.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004776 Supported Supported Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 24: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 23: Non-specific - Transcription" "Cluster 51: Secretory epithelial cells - Mixed function" 41 Nucleoplasm "HPA004776: " "unprognostic (8.57e-3)" "unprognostic (1.17e-1)" "unprognostic (3.61e-2)" "unprognostic (4.91e-2)" "unprognostic (1.40e-2)" "unprognostic (1.15e-1)" "unprognostic (2.19e-2)" "unprognostic (9.15e-2)" "unprognostic (1.14e-1)" "unprognostic (8.12e-2)" "potential prognostic favorable (2.03e-8)" "unprognostic (8.64e-3)" "unprognostic (1.06e-1)" "unprognostic (1.00e-1)" "unprognostic (1.94e-1)" "unprognostic (1.68e-2)" "unprognostic (2.55e-1)" "unprognostic (5.10e-2)" "unprognostic (1.14e-1)" "unprognostic (1.09e-2)" "unprognostic (1.63e-2)" "unprognostic (3.57e-1)" "unprognostic (9.12e-2)" "unprognostic (2.73e-2)" "unprognostic (2.00e-2)" "unprognostic (1.08e-2)" "unprognostic (3.04e-1)" "unprognostic (1.08e-2)" "unprognostic (5.25e-2)" AKAP8L "HAP95, NAKAP95" ENSG00000011243 "A-kinase anchoring protein 8 like" Q9ULX6 19 15380050-15419141 "Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042485, HPA042546" Enhanced Supported "Nuclear speckles" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 34: Non-specific - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 77 "Nuclear speckles" "HPA042485: , HPA042546: " "unprognostic (3.78e-1)" "unprognostic (8.93e-2)" "unprognostic (7.84e-2)" "unprognostic (2.32e-2)" "unprognostic (8.34e-2)" "unprognostic (4.66e-2)" "unprognostic (1.39e-1)" "unprognostic (1.34e-3)" "unprognostic (6.72e-2)" "unprognostic (1.12e-1)" "unprognostic (1.67e-2)" "unprognostic (6.89e-3)" "unprognostic (5.26e-2)" "potential prognostic unfavorable (1.77e-8)" "unprognostic (8.49e-2)" "unprognostic (1.87e-1)" "unprognostic (9.93e-2)" "unprognostic (2.02e-2)" "unprognostic (2.79e-2)" "unprognostic (4.90e-2)" "unprognostic (2.09e-1)" "unprognostic (3.23e-3)" "potential prognostic unfavorable (3.69e-4)" "unprognostic (3.36e-3)" "unprognostic (1.05e-2)" "unprognostic (1.24e-3)" "unprognostic (5.95e-2)" "unprognostic (1.02e-2)" "unprognostic (6.47e-2)" "unprognostic (1.35e-1)" "unprognostic (4.86e-1)" AKAP9 "AKAP350, AKAP450, CG-NAP, HYPERION, KIAA0803, LQT11, MU-RMS-40.16A, PPP1R45, PRKA9, YOTIAO" ENSG00000127914 "A-kinase anchoring protein 9" Q99996 7 91940840-92110673 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 1923.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008548, CAB012909, HPA026109" Supported Enhanced "Golgi apparatus,Vesicles,Centrosome" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 16: Non-specific - Transcription" "Cluster 39: Non-specific - Transcription" "Cluster 79: Photoreceptor cells - Phototransduction" 29 "Golgi apparatus" "Vesicles, Centrosome" "CAB012909: , HPA008548: , HPA026109: " "unprognostic (1.60e-1)" "unprognostic (2.22e-1)" "unprognostic (4.74e-1)" "potential prognostic favorable (9.75e-4)" "unprognostic (1.97e-1)" "unprognostic (7.02e-2)" "unprognostic (1.00e-1)" "unprognostic (4.28e-3)" "unprognostic (1.12e-1)" "unprognostic (1.02e-1)" "validated prognostic favorable (8.94e-5)" "validated prognostic favorable (1.92e-4)" "unprognostic (1.77e-2)" "unprognostic (1.90e-1)" "unprognostic (1.38e-1)" "unprognostic (1.39e-1)" "unprognostic (1.13e-1)" "unprognostic (1.55e-3)" "unprognostic (1.13e-1)" "unprognostic (2.02e-1)" "unprognostic (9.95e-2)" "unprognostic (2.64e-2)" "unprognostic (9.37e-2)" "unprognostic (2.97e-1)" "unprognostic (1.05e-1)" "unprognostic (1.15e-2)" "unprognostic (2.08e-1)" "unprognostic (1.10e-1)" "unprognostic (2.55e-2)" "unprognostic (9.80e-2)" "unprognostic (5.39e-1)" AKIP1 "BCA3, C11orf17" ENSG00000166452 "A-kinase interacting protein 1" Q9NQ31 11 8911139-8920084 "Predicted intracellular proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 104.8;Hofbauer cells: 88.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061391 Supported Nucleoplasm NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 46: Brainstem - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 12 Nucleoplasm "HPA061391: " "unprognostic (5.63e-2)" "unprognostic (1.96e-2)" "unprognostic (1.10e-1)" "unprognostic (3.75e-1)" "unprognostic (1.04e-1)" "unprognostic (7.56e-3)" "unprognostic (3.12e-2)" "unprognostic (1.08e-2)" "unprognostic (4.97e-2)" "unprognostic (3.81e-2)" "unprognostic (8.86e-2)" "unprognostic (5.53e-2)" "potential prognostic unfavorable (2.09e-10)" "unprognostic (7.23e-2)" "unprognostic (4.61e-2)" "unprognostic (4.25e-2)" "unprognostic (1.01e-1)" "unprognostic (1.83e-1)" "unprognostic (3.30e-1)" "unprognostic (3.45e-3)" "unprognostic (3.06e-2)" "unprognostic (9.21e-2)" "unprognostic (2.50e-1)" "unprognostic (1.51e-1)" "unprognostic (1.40e-1)" "unprognostic (4.21e-2)" "unprognostic (3.32e-1)" "unprognostic (3.56e-1)" "unprognostic (1.79e-2)" "unprognostic (6.08e-2)" AKIRIN1 "C1orf108, FLJ12666" ENSG00000174574 "Akirin 1" Q9H9L7 1 38991276-39006059 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 1867.3;Late spermatids: 1810.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051871 Approved Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 7 Nucleoplasm "Nuclear membrane" "HPA051871: " "unprognostic (5.19e-2)" "unprognostic (2.80e-1)" "unprognostic (5.35e-2)" "potential prognostic unfavorable (2.33e-4)" "unprognostic (1.07e-1)" "unprognostic (2.70e-1)" "unprognostic (3.65e-2)" "unprognostic (4.31e-2)" "unprognostic (6.16e-2)" "unprognostic (4.27e-2)" "unprognostic (1.68e-3)" "unprognostic (9.87e-2)" "unprognostic (3.18e-1)" "potential prognostic unfavorable (1.12e-7)" "unprognostic (7.41e-3)" "unprognostic (3.81e-1)" "unprognostic (1.63e-1)" "unprognostic (1.04e-1)" "unprognostic (3.66e-2)" "unprognostic (1.32e-2)" "unprognostic (2.08e-2)" "unprognostic (2.99e-2)" "unprognostic (3.00e-1)" "unprognostic (4.22e-2)" "unprognostic (3.59e-1)" "unprognostic (2.71e-2)" "unprognostic (9.25e-2)" "unprognostic (2.55e-1)" "unprognostic (6.55e-2)" "unprognostic (1.28e-2)" "unprognostic (1.25e-1)" AKIRIN2 "C6orf166, dJ486L4.2, FLJ10342" ENSG00000135334 "Akirin 2" Q53H80 6 87674860-87702233 "Essential proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity, Protein transport, Transcription, Transcription regulation, Transport" "Developmental protein, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 530.7;Neutrophils: 509.5;Platelets: 701.0;Syncytiotrophoblasts: 267.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064239 Supported Nucleoplasm No Yes "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 32 Nucleoplasm "HPA064239: " "unprognostic (2.09e-1)" "unprognostic (2.05e-2)" "unprognostic (7.15e-2)" "unprognostic (1.20e-1)" "unprognostic (1.04e-1)" "unprognostic (1.97e-1)" "unprognostic (1.21e-1)" "unprognostic (2.36e-1)" "unprognostic (8.76e-3)" "unprognostic (1.36e-2)" "unprognostic (6.94e-2)" "unprognostic (5.83e-3)" "unprognostic (7.05e-2)" "unprognostic (1.05e-1)" "unprognostic (1.69e-1)" "unprognostic (6.55e-2)" "unprognostic (4.02e-2)" "unprognostic (4.39e-2)" "unprognostic (1.89e-1)" "unprognostic (5.03e-2)" "unprognostic (2.17e-1)" "unprognostic (4.74e-2)" "unprognostic (1.65e-3)" "unprognostic (1.31e-1)" "unprognostic (2.58e-2)" "unprognostic (1.13e-1)" "unprognostic (1.92e-1)" "unprognostic (1.75e-1)" "unprognostic (5.11e-2)" "unprognostic (1.09e-2)" "unprognostic (1.01e-1)" AKNA KIAA1968 ENSG00000106948 "AT-hook transcription factor" Q7Z591 9 114334156-114394405 "Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 105.7" "Cell type enhanced" "Detected in many" "B-cells: 150.3;Cone photoreceptor cells: 147.0;Innate lymphoid cells: 139.9;Mast cells: 147.8;Neutrophils: 379.4;NK-cells: 456.1;Rod photoreceptor cells: 182.1;T-cells: 306.8;Thymocytes: 171.1" "Cell type enhanced" "Detected in many" "ependymal cell: 112.9;leukocyte: 305.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Leukemia: 60.1;lymphoma: 68.3;Myeloma: 45.2" "Colon - T-cells, Spleen - B-cells (Spleen), Testis - Late spermatids, Thyroid gland - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA052367, HPA063993" Supported "Nucleoplasm,Nucleoli fibrillar center,Centrosome,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 46: Brainstem - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 2 Nucleoplasm "Nucleoli fibrillar center, Centrosome, Cytosol" "HPA052367: , HPA063993: " "unprognostic (3.78e-2)" "unprognostic (2.10e-2)" "unprognostic (6.04e-3)" "unprognostic (3.43e-2)" "unprognostic (3.16e-2)" "unprognostic (2.11e-1)" "unprognostic (3.02e-1)" "unprognostic (1.67e-3)" "potential prognostic favorable (6.10e-4)" "unprognostic (2.64e-2)" "unprognostic (8.95e-2)" "unprognostic (4.32e-1)" "unprognostic (9.29e-2)" "unprognostic (1.36e-1)" "unprognostic (5.55e-3)" "unprognostic (4.54e-3)" "unprognostic (1.16e-1)" "unprognostic (4.28e-2)" "unprognostic (7.80e-2)" "unprognostic (9.21e-2)" "unprognostic (1.01e-2)" "unprognostic (6.36e-2)" "unprognostic (1.12e-1)" "unprognostic (1.58e-1)" "unprognostic (5.80e-3)" "unprognostic (1.66e-1)" "unprognostic (6.66e-2)" "unprognostic (1.80e-2)" "unprognostic (8.87e-3)" "unprognostic (1.55e-1)" "unprognostic (1.03e-1)" AKNAD1 "C1orf62, MGC26989" ENSG00000162641 "AKNA domain containing 1" Q5T1N1 1 108815898-108963484 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 14 "testis: 4.6" "Cell type enhanced" "Detected in many" "Astrocytes: 37.1;Bergmann glia: 62.2;Brain excitatory neurons: 27.5;Brain inhibitory neurons: 33.1;Choroid plexus epithelial cells: 27.0;Early spermatids: 225.0;Ependymal cells: 35.5;Late primary spermatocytes: 70.7;Late spermatids: 35.9;Oligodendrocyte progenitor cells: 52.3;Oligodendrocytes: 50.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in single" "Bladder Urothelial Carcinoma (TCGA): 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA030270, HPA030271, HPA030272" Uncertain Approved "Microtubules,Cytokinetic bridge,Cytosol" Yes NA "Cluster 6: Testis - Spermatogenesis" "Cluster 11: Neuronal - Sensory perception" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" Cytosol "Microtubules, Cytokinetic bridge" "HPA030270: , HPA030271: , HPA030272: " "unprognostic (1.18e-1)" "potential prognostic favorable (8.81e-4)" AKR1A1 "ALR, DD3" ENSG00000117448 "Aldo-keto reductase family 1 member A1" P14550 1 45550543-45570049 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Breast lactating cells: 608.5;Enterocytes: 812.2;Esophageal apical cells: 400.0;Esophageal suprabasal cells: 399.2;Hofbauer cells: 567.0" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 95.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006246, HPA017919, HPA019649, HPA027734" Approved Supported Nucleoplasm,Cytosol NA NA 5800000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 37: Non-specific - mRNA processing" "Cluster 1: Enterocytes - Absorption and Digestion" 10 Cytosol Nucleoplasm "CAB006246: , HPA017919: , HPA019649: , HPA027734: " "unprognostic (2.58e-1)" "unprognostic (6.60e-2)" "unprognostic (1.70e-1)" "unprognostic (5.73e-3)" "unprognostic (5.10e-2)" "unprognostic (6.94e-2)" "unprognostic (4.55e-1)" "unprognostic (7.27e-2)" "unprognostic (1.84e-2)" "unprognostic (5.01e-1)" "potential prognostic favorable (1.01e-4)" "unprognostic (7.89e-2)" "unprognostic (5.59e-2)" "unprognostic (4.07e-2)" "unprognostic (7.96e-2)" "unprognostic (6.89e-3)" "unprognostic (2.83e-2)" "unprognostic (1.69e-1)" "unprognostic (2.07e-1)" "unprognostic (9.95e-2)" "unprognostic (8.48e-2)" "unprognostic (4.08e-2)" "unprognostic (1.61e-3)" "unprognostic (3.77e-1)" "unprognostic (5.58e-2)" "unprognostic (5.94e-2)" "unprognostic (2.88e-1)" "unprognostic (1.32e-2)" "unprognostic (1.12e-1)" "unprognostic (1.27e-1)" "unprognostic (1.43e-2)" AKR1B1 "ALDR1, AR" ENSG00000085662 "Aldo-keto reductase family 1 member B" P15121 7 134442356-134459284 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "adrenal gland: 3016.7" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 909.6;Cytotrophoblasts: 1274.3;Extravillous trophoblasts: 1456.7;Hofbauer cells: 477.1;Migrating cytotrophoblasts: 1520.7;Oocytes: 686.2;Syncytiotrophoblasts: 2450.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney cancer: 1445.2" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026425, CAB027391, CAB047353, HPA052751" Enhanced Supported Nucleoplasm,Cytosol No No 1600000 "Cluster 39: T-cells - T-cell receptor" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 9 Cytosol Nucleoplasm "CAB027391: , CAB047353: , HPA026425: , HPA052751: " "unprognostic (3.13e-3)" "unprognostic (9.62e-2)" "unprognostic (1.23e-1)" "unprognostic (2.93e-2)" "unprognostic (8.67e-2)" "unprognostic (2.05e-1)" "potential prognostic unfavorable (1.19e-5)" "unprognostic (2.06e-1)" "unprognostic (2.14e-1)" "unprognostic (1.61e-3)" "unprognostic (2.98e-2)" "unprognostic (6.42e-2)" "unprognostic (2.21e-1)" "unprognostic (2.48e-2)" "unprognostic (1.32e-1)" "unprognostic (2.73e-1)" "unprognostic (2.18e-1)" "unprognostic (1.71e-2)" "unprognostic (1.06e-1)" "unprognostic (2.17e-1)" "unprognostic (1.70e-1)" "unprognostic (3.17e-2)" "unprognostic (3.89e-1)" "unprognostic (6.93e-2)" "unprognostic (2.53e-1)" "unprognostic (5.75e-2)" "unprognostic (2.89e-2)" "potential prognostic unfavorable (6.55e-6)" "unprognostic (2.72e-1)" "unprognostic (2.90e-2)" "unprognostic (1.25e-2)" AKR1B10 "AKR1B11, AKR1B12, ALDRLn, ARL-1, ARL1, HIS, HSI" ENSG00000198074 "Aldo-keto reductase family 1 member B10" O60218 7 134527567-134541412 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 211.0;intestine: 577.8;stomach 1: 408.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 226.2;Cholangiocytes: 145.7;Colonocytes: 167.6;Enterocytes: 304.0;Esophageal apical cells: 141.7;Esophageal basal cells: 569.2;Esophageal suprabasal cells: 880.0;Foveolar cells: 853.4;Suprabasal keratinocytes: 496.9" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 484.3;Lung Squamous Cell Carcinoma (TCGA): 382.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "Gallbladder cancer: 2714.5" "Colon - Colon enterocytes, Pituitary gland - Thyrotropes, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "HPA020280, CAB070163, HPA073633" Enhanced Supported "Plasma membrane,Cytosol" "Secreted to digestive system" Enzyme NA NA 250000 "Cluster 77: Intestine - Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 85: Squamous epithelial cells - Keratinization" 13 Cytosol "Plasma membrane" "CAB070163: , HPA020280: , HPA073633: " "unprognostic (5.66e-1)" "unprognostic (6.98e-3)" "unprognostic (2.01e-1)" "unprognostic (1.45e-2)" "unprognostic (2.27e-2)" "unprognostic (2.45e-1)" "unprognostic (1.80e-1)" "unprognostic (2.72e-1)" "validated prognostic unfavorable (5.83e-8)" "validated prognostic unfavorable (5.94e-4)" "potential prognostic unfavorable (1.35e-5)" "unprognostic (1.67e-3)" "unprognostic (1.36e-1)" "unprognostic (2.15e-2)" "unprognostic (1.12e-1)" "unprognostic (1.29e-1)" "unprognostic (1.70e-1)" "unprognostic (3.97e-2)" "unprognostic (2.39e-1)" "unprognostic (3.43e-3)" "unprognostic (4.07e-3)" "unprognostic (9.07e-3)" "unprognostic (2.07e-1)" "unprognostic (1.83e-1)" "unprognostic (2.36e-1)" "unprognostic (1.46e-1)" "unprognostic (2.25e-3)" "unprognostic (1.24e-1)" AKR1B15 ENSG00000227471 "Aldo-keto reductase family 1 member B15" C9JRZ8 7 134549110-134579875 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "breast: 156.9" "Cell type enhanced" "Detected in some" "Adipocytes: 3.0;Early spermatids: 3.3;Esophageal apical cells: 4.8;Esophageal suprabasal cells: 3.8;Granulosa cells: 3.2;Late spermatids: 5.9;Myonuclei: 2.6;Myosatellite cells: 8.0;Parietal cells: 3.5;Suprabasal keratinocytes: 6.3;Syncytiotrophoblasts: 26.8;Thymic myoid cells: 5.4" "Cell type enhanced" "Detected in single" "committed oligodendrocyte precursor: 1.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 7.3" "Stomach - Gastric mucous cells, Testis - Spermatogonia" "HPA020280, HPA073633" Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 55: Breast - Lactation" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 1 Cytosol "Plasma membrane" "HPA020280: , HPA073633: " "unprognostic (6.11e-3)" "unprognostic (1.97e-2)" "unprognostic (5.12e-1)" "unprognostic (1.39e-3)" "unprognostic (9.75e-3)" "unprognostic (3.52e-2)" "unprognostic (1.35e-1)" "potential prognostic unfavorable (1.57e-5)" "potential prognostic unfavorable (3.14e-4)" "unprognostic (2.19e-1)" "unprognostic (4.85e-2)" "potential prognostic unfavorable (8.94e-4)" "unprognostic (1.22e-1)" "unprognostic (1.09e-1)" "unprognostic (2.71e-1)" "unprognostic (5.99e-2)" "unprognostic (1.54e-1)" "unprognostic (1.24e-1)" "unprognostic (2.58e-1)" "unprognostic (1.57e-1)" "unprognostic (2.70e-1)" AKR1C1 "DD1, DDH, DDH1, HAKRC, MBAB" ENSG00000187134 "Aldo-keto reductase family 1 member C1" Q04828 10 4963253-4983283 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 581.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 195.1;Cholangiocytes: 337.7;Conjunctival goblet cells: 571.8;Esophageal basal cells: 191.7;Fibroblasts: 185.5;Foveolar cells: 323.8;Hepatocytes: 794.7;Ocular epithelial cells: 260.1;Respiratory secretory cells: 379.7;Suprabasal keratinocytes: 184.6;Urothelial cells: 343.8" "Cell type enhanced" "Detected in many" "fibroblast: 81.0" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 650.3;Lung Squamous Cell Carcinoma (TCGA): 1045.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.5" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Esophageal cancer: 532.2;Gallbladder cancer: 872.6;liver cancer: 767.2" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Stomach - Gastric mucous cells" "CAB047303, HPA068265" Enhanced Enhanced "Endoplasmic reticulum,Cytosol" NA NA 3400000 "Cluster 41: Basophils - Unknown function" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 49: Hindbrain - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 103: Non-specific - Basic cellular processes" 10 "Endoplasmic reticulum, Cytosol" "CAB047303: , HPA068265: " "unprognostic (2.01e-1)" "unprognostic (1.99e-2)" "unprognostic (3.00e-2)" "unprognostic (1.84e-2)" "unprognostic (1.27e-1)" "unprognostic (3.08e-2)" "unprognostic (4.03e-2)" "potential prognostic favorable (2.55e-4)" "unprognostic (9.85e-2)" "unprognostic (7.71e-2)" "potential prognostic favorable (3.12e-8)" "unprognostic (9.43e-2)" "unprognostic (4.26e-1)" "validated prognostic unfavorable (1.48e-4)" "validated prognostic unfavorable (3.42e-6)" "unprognostic (1.69e-1)" "unprognostic (3.75e-3)" "unprognostic (8.63e-2)" "unprognostic (5.59e-2)" "unprognostic (3.82e-2)" "unprognostic (8.97e-2)" "unprognostic (1.83e-1)" "unprognostic (1.22e-1)" "unprognostic (8.63e-3)" "unprognostic (1.40e-1)" "unprognostic (2.83e-1)" "unprognostic (1.77e-1)" "unprognostic (7.76e-2)" "unprognostic (2.12e-1)" "unprognostic (1.78e-2)" "unprognostic (3.07e-2)" AKR1C2 "BABP, DD, DD2, DDH2, HAKRD, MCDR2, TDD" ENSG00000151632 "Aldo-keto reductase family 1 member C2" P52895 10 4987775-5018031 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 316.8;liver: 448.7" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 715.5;Esophageal basal cells: 173.7;Foveolar cells: 332.8;Hepatocytes: 561.7;Ocular epithelial cells: 300.8;Prostatic hillock cells: 277.0;Respiratory secretory cells: 259.3;Salivary duct cells: 704.0;Suprabasal keratinocytes: 178.5;Urothelial cells: 919.4" "Cell type enriched" "Detected in many" 8 "fibroblast: 183.3" "Cancer enhanced" "Detected in all" "Lung Squamous Cell Carcinoma (TCGA): 964.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Bladder cancer: 359.3;Esophageal cancer: 1222.9;Gallbladder cancer: 1184.3;liver cancer: 557.1;lung cancer: 433.6" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Stomach - Gastric mucous cells, Testis - Peritubular cells" "CAB047304, HPA068265" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Endoplasmic reticulum,Cytosol" NA NA 3300000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 45: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 69: Urothelial cells - Basic cellular functions" 13 "Nucleoplasm, Cytosol" "Nucleoli fibrillar center, Endoplasmic reticulum" "CAB047304: , HPA068265: " "unprognostic (1.84e-1)" "unprognostic (1.04e-1)" "unprognostic (7.61e-2)" "unprognostic (9.47e-3)" "unprognostic (2.40e-2)" "unprognostic (4.82e-2)" "unprognostic (3.08e-1)" "unprognostic (5.99e-2)" "unprognostic (1.75e-2)" "unprognostic (2.86e-1)" "potential prognostic favorable (7.86e-6)" "unprognostic (1.17e-1)" "unprognostic (3.16e-2)" "unprognostic (7.97e-3)" "unprognostic (1.20e-1)" "unprognostic (7.17e-2)" "unprognostic (5.92e-2)" "unprognostic (3.34e-1)" "unprognostic (3.86e-1)" "unprognostic (1.46e-1)" "unprognostic (8.34e-2)" "unprognostic (3.96e-2)" "unprognostic (9.16e-3)" "unprognostic (3.91e-2)" "unprognostic (5.11e-2)" "unprognostic (1.71e-1)" "unprognostic (9.13e-2)" "unprognostic (1.34e-2)" "unprognostic (4.27e-2)" "unprognostic (1.58e-3)" "unprognostic (6.35e-3)" AKR1C3 "DDX, HAKRB, HSD17B5, KIAA0119, PGFS" ENSG00000196139 "Aldo-keto reductase family 1 member C3" P42330 10 5035354-5107686 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 415.2" "Cell type enhanced" "Detected in many" "Cholangiocytes: 290.7;Enteric transient amplifying cells: 265.8;Enterocytes: 515.0;Foveolar cells: 432.1;Hematopoietic stem cells: 200.4;Hepatocytes: 414.0;Urothelial cells: 388.5" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Lung Squamous Cell Carcinoma (TCGA): 603.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 244.9;gdT-cell: 102.8" "Group enriched" "Detected in many" 4 "granulocytes: 244.9;T-cells: 102.8" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 1748.7" "Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Stomach - Gastric mucous cells" "CAB010874, HPA068265" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Endoplasmic reticulum,Cytosol" NA NA 2700000 "Cluster 41: Basophils - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 39: Astrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 68: Foveolar cells - Mucosal defense" 10 "Nucleoplasm, Cytosol" "Nucleoli fibrillar center, Endoplasmic reticulum" "CAB010874: , HPA068265: " "unprognostic (2.23e-1)" "unprognostic (1.52e-2)" "unprognostic (1.25e-1)" "unprognostic (2.96e-2)" "unprognostic (1.08e-1)" "unprognostic (1.09e-1)" "unprognostic (7.08e-2)" "potential prognostic favorable (1.50e-4)" "unprognostic (1.86e-3)" "unprognostic (3.73e-1)" "potential prognostic favorable (8.42e-5)" "unprognostic (6.47e-2)" "potential prognostic unfavorable (3.70e-4)" "validated prognostic unfavorable (5.07e-6)" "validated prognostic unfavorable (2.51e-7)" "unprognostic (3.93e-2)" "unprognostic (2.97e-2)" "unprognostic (4.07e-2)" "unprognostic (1.51e-1)" "unprognostic (6.61e-2)" "unprognostic (1.21e-1)" "unprognostic (6.33e-2)" "unprognostic (2.69e-1)" "unprognostic (1.30e-1)" "unprognostic (2.50e-1)" "unprognostic (3.97e-2)" "unprognostic (1.75e-1)" "unprognostic (3.68e-1)" "unprognostic (1.38e-1)" "potential prognostic unfavorable (1.44e-5)" "unprognostic (3.50e-2)" AKR1C4 "3-alpha-HSD, C11, CDR, CHDR, DD4, HAKRA, MGC22581" ENSG00000198610 "Aldo-keto reductase family 1 member C4" P17516 10 5195462-5218949 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "liver: 670.3" "Cell type enriched" "Detected in some" 27 "Hepatocytes: 807.8" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 87 "Liver Hepatocellular Carcinoma (TCGA): 254.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bile duct cancer: 4.1;colorectal cancer: 3.6;Gastric cancer: 1.8;liver cancer: 6.8" "Liver - Hepatocytes, Testis - Early spermatids" "HPA044720, HPA068265" Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center,Endoplasmic reticulum,Cytosol" NA NA 2500000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 7: Liver cancer - Metabolism" "Cluster 93: Hepatocytes - Bile production & excretion" 4 "Nucleoplasm, Cytosol" "Nucleoli fibrillar center, Endoplasmic reticulum" "HPA044720: , HPA068265: " "unprognostic (1.88e-1)" "unprognostic (1.40e-1)" "unprognostic (2.25e-1)" "potential prognostic unfavorable (2.52e-5)" "unprognostic (4.54e-2)" "unprognostic (3.87e-1)" "unprognostic (1.86e-1)" "unprognostic (1.55e-2)" "unprognostic (3.65e-2)" "unprognostic (5.77e-2)" "unprognostic (1.08e-1)" "unprognostic (1.79e-1)" AKR1C8 "AKR1C8P, AKR1CL1" ENSG00000264006 "Aldo-keto reductase family 1 member C8" Q5T2L2 10 5153920-5185187 "Predicted intracellular proteins" Oxidoreductase "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 11 "epididymis: 2.8;liver: 6.7" "Group enriched" "Detected in some" 8 "Adipocytes: 36.6;Choroid plexus epithelial cells: 55.0;Hepatocytes: 54.2;Sertoli cells: 30.5" "Cell type enriched" "Detected in some" 19 "choroid plexus epithelial cell: 42.7" "Not detected" "Not detected" "Region enriched" "Detected in single" 7 "choroid plexus: 6.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes" "Low region specificity" "Detected in some" NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 36: Choroid plexus - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 3 "unprognostic (1.07e-1)" AKR1D1 SRD5B1 ENSG00000122787 "Aldo-keto reductase family 1 member D1" P51857 7 138002324-138118305 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Bile acid catabolism, Lipid degradation, Lipid metabolism, Steroid metabolism" Oxidoreductase "Disease variant, FDA approved drug targets, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 82 "liver: 398.8" "Group enriched" "Detected in some" 4 "Early spermatids: 157.1;Hepatocytes: 306.0;Late spermatids: 374.7" "Low cell type specificity" "Detected in some" "Cancer enriched" "Detected in single" 53 "Liver Hepatocellular Carcinoma (TCGA): 34.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "liver cancer: 2.4" "Liver - Hepatocytes, Minor Salivary Gland - Plasma cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA057002 Enhanced Approved Nucleoplasm,Cytosol No NA 130000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 48: Non-specific - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 93: Hepatocytes - Bile production & excretion" 5 Nucleoplasm Cytosol "HPA057002: " "potential prognostic favorable (8.12e-4)" "unprognostic (2.27e-3)" AKR1E2 "AKR1CL2, AKRDC1, htAKR, HTSP1, MGC10612" ENSG00000165568 "Aldo-keto reductase family 1 member E2" Q96JD6 10 4786629-4848062 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 17.2" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 79.3;Early spermatids: 228.1;Late primary spermatocytes: 101.9;Late spermatids: 258.0;Retinal ganglion cells: 50.2;Retinal horizontal cells: 54.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 17.6" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037822 Enhanced Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 1: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" "Nucleoplasm, Golgi apparatus" Cytosol "HPA037822: " "potential prognostic unfavorable (1.07e-4)" "potential prognostic unfavorable (7.72e-4)" "unprognostic (9.38e-2)" "unprognostic (2.31e-3)" "unprognostic (1.51e-1)" "unprognostic (7.72e-2)" "unprognostic (7.19e-2)" "unprognostic (1.31e-1)" "unprognostic (5.11e-3)" "unprognostic (2.55e-1)" "unprognostic (2.43e-1)" "unprognostic (2.62e-1)" "unprognostic (8.72e-3)" "unprognostic (1.76e-1)" "unprognostic (1.83e-1)" "unprognostic (2.12e-1)" "unprognostic (2.82e-1)" "unprognostic (3.78e-1)" "unprognostic (1.92e-1)" "unprognostic (1.07e-1)" "unprognostic (2.37e-1)" "unprognostic (4.13e-2)" "unprognostic (4.81e-2)" "unprognostic (1.05e-1)" AKR7A2 AFAR ENSG00000053371 "Aldo-keto reductase family 7 member A2" O43488 1 19303965-19312144 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 293.5;Enterocytes: 242.6;Megakaryocytes: 253.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "CAB032587, CAB032841, HPA064638" Enhanced Supported "Golgi apparatus,Cytosol" NA NA 1500000 "Cluster 13: Non-specific - Mitochondria" "Cluster 70: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 37: Non-specific - mRNA processing" "Cluster 97: Non-specific - Cellular respiration" 14 Cytosol "Golgi apparatus" "CAB032587: , CAB032841: , HPA064638: " "unprognostic (1.10e-1)" "unprognostic (6.35e-2)" "unprognostic (6.98e-2)" "unprognostic (5.90e-2)" "unprognostic (6.58e-2)" "unprognostic (1.16e-1)" "unprognostic (9.75e-2)" "unprognostic (1.46e-1)" "unprognostic (1.37e-1)" "unprognostic (3.45e-2)" "potential prognostic favorable (3.13e-7)" "unprognostic (2.85e-2)" "unprognostic (4.28e-3)" "unprognostic (1.98e-3)" "unprognostic (1.30e-3)" "unprognostic (8.59e-2)" "unprognostic (1.22e-1)" "unprognostic (1.37e-1)" "unprognostic (4.59e-1)" "unprognostic (7.94e-3)" "unprognostic (3.23e-2)" "unprognostic (1.21e-1)" "unprognostic (1.11e-2)" "unprognostic (2.24e-1)" "unprognostic (1.95e-1)" "unprognostic (1.61e-1)" "unprognostic (2.04e-2)" "unprognostic (7.00e-2)" "unprognostic (3.70e-2)" "unprognostic (2.69e-1)" "unprognostic (3.41e-2)" AKR7A3 ENSG00000162482 "Aldo-keto reductase family 7 member A3" O95154 1 19282573-19288770 "Metabolic proteins, Predicted intracellular proteins" Detoxification Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 234.0;liver: 217.7;pancreas: 400.4;stomach 1: 305.6" "Group enriched" "Detected in many" 4 "Enterocytes: 954.9;Parietal cells: 1424.9" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 10.2" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 91.8" "Region enriched" "Detected in all" 5 "choroid plexus: 35.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 16.8;colorectal cancer: 19.5;Gastric cancer: 18.9" "Breast - Breast glandular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Stomach - Parietal cells" HPA064638 Supported "Golgi apparatus,Cytosol" NA NA 1600000 "Cluster 60: Stomach - Digestion" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 9 Cytosol "Golgi apparatus" "HPA064638: " "unprognostic (2.68e-2)" "unprognostic (2.27e-1)" "unprognostic (2.59e-1)" "unprognostic (3.13e-3)" "unprognostic (7.34e-2)" "unprognostic (9.20e-2)" "unprognostic (2.30e-2)" "unprognostic (6.99e-2)" "unprognostic (1.33e-1)" "unprognostic (4.66e-2)" "potential prognostic favorable (5.06e-7)" "unprognostic (5.09e-3)" "potential prognostic favorable (6.62e-7)" "unprognostic (1.60e-3)" "unprognostic (2.51e-3)" "unprognostic (2.62e-2)" "unprognostic (1.15e-2)" "unprognostic (6.42e-2)" "unprognostic (6.98e-2)" "unprognostic (5.00e-2)" "unprognostic (1.35e-1)" "unprognostic (2.30e-2)" "unprognostic (9.47e-2)" "unprognostic (1.28e-1)" "unprognostic (5.07e-2)" "unprognostic (1.19e-1)" "unprognostic (1.24e-1)" "unprognostic (4.26e-2)" "unprognostic (2.18e-1)" AKR7L AFAR3 ENSG00000211454 "Aldo-keto reductase family 7 like (gene/pseudogene)" 1 19265982-19274194 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 58.4;liver: 34.7;stomach 1: 23.5" "Cell type enhanced" "Detected in some" "Enteric transient amplifying cells: 7.8;Enterocytes: 59.6;Foveolar cells: 18.5;Hepatocytes: 17.3;Mucous neck cells: 13.8;Pancreatic acinar cells: 7.8" "Low cell type specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064638 Supported "Golgi apparatus,Cytosol" NA NA "Cluster 77: Intestine - Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 1: Enterocytes - Absorption and Digestion" Cytosol "Golgi apparatus" "HPA064638: " AKT1 "AKT, PKB, PRKBA, RAC, RAC-alpha" ENSG00000142208 "AKT serine/threonine kinase 1" P31749 14 104769349-104795751 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins, Transporters" "Apoptosis, Carbohydrate metabolism, Glucose metabolism, Glycogen biosynthesis, Glycogen metabolism, Neurogenesis, Sugar transport, Translation regulation, Transport" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 152.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 24.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002891, CAB003765, CAB080436" Supported Approved "Nucleoplasm,Microtubules,Primary cilium,Basal body,Perinuclear theca,Calyx,Principal piece,End piece" NA NA 7600 "Cluster 45: Eosinophils - Unknown function" "Cluster 55: Breast - Lactation" "Cluster 43: Hindbrain - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 4: Breast lactating luminal cells - Lactation" 399 "Nucleoplasm, Microtubules, Principal piece, End piece" "Primary cilium, Basal body, Perinuclear theca, Calyx" "CAB003765: , CAB080436: , HPA002891: " "unprognostic (1.20e-1)" "unprognostic (1.22e-1)" "unprognostic (6.07e-2)" "unprognostic (3.52e-2)" "unprognostic (5.14e-2)" "unprognostic (2.32e-2)" "unprognostic (2.25e-1)" "unprognostic (6.34e-2)" "unprognostic (1.25e-2)" "unprognostic (2.91e-2)" "potential prognostic favorable (1.15e-4)" "unprognostic (1.19e-3)" "unprognostic (1.77e-3)" "potential prognostic unfavorable (7.84e-5)" "unprognostic (8.90e-2)" "unprognostic (2.68e-1)" "unprognostic (2.54e-1)" "unprognostic (6.96e-2)" "unprognostic (1.43e-1)" "unprognostic (2.84e-2)" "unprognostic (1.04e-1)" "unprognostic (9.22e-2)" "unprognostic (1.75e-1)" "unprognostic (1.38e-1)" "unprognostic (6.70e-2)" "unprognostic (3.27e-1)" "unprognostic (1.95e-2)" "unprognostic (1.23e-1)" "unprognostic (1.25e-1)" "unprognostic (2.26e-1)" "unprognostic (1.10e-1)" AKT1S1 "Lobe, MGC2865, PRAS40" ENSG00000204673 "AKT1 substrate 1" Q96B36 19 49869033-49878459 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Epicardial cells: 2.3;Late spermatids: 2.0;Parietal cells: 1.8;Respiratory ionocytes: 5.1;Syncytiotrophoblasts: 3.0;Thymic myoid cells: 2.7" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB021903, HPA043590, HPA064427, HPA075510" Approved Supported Cytosol NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 24: Non-specific - Transcription" "Cluster 19: Astrocytes - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 108: Fibroblasts - ECM organization" 25 Cytosol "CAB021903: , HPA043590: , HPA064427: , HPA075510: " "unprognostic (1.42e-1)" "unprognostic (1.61e-2)" "unprognostic (3.38e-1)" "unprognostic (1.53e-2)" "unprognostic (1.01e-1)" "unprognostic (3.43e-2)" "unprognostic (3.25e-1)" "unprognostic (9.58e-2)" "unprognostic (1.47e-1)" "unprognostic (3.07e-1)" "unprognostic (1.08e-1)" "unprognostic (4.29e-3)" "unprognostic (8.12e-2)" "potential prognostic unfavorable (5.56e-5)" "unprognostic (1.19e-2)" "potential prognostic unfavorable (8.17e-4)" "unprognostic (1.96e-2)" "unprognostic (2.30e-1)" "unprognostic (1.28e-1)" "unprognostic (6.31e-2)" "unprognostic (7.38e-3)" "unprognostic (1.56e-3)" "unprognostic (1.09e-1)" "unprognostic (9.34e-3)" "unprognostic (3.83e-1)" "unprognostic (4.17e-1)" "unprognostic (1.99e-1)" "unprognostic (4.95e-2)" "unprognostic (2.54e-1)" "unprognostic (6.97e-3)" "unprognostic (8.93e-2)" AKT2 PKBbeta ENSG00000105221 "AKT serine/threonine kinase 2" P31751 19 40230317-40285536 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Carbohydrate metabolism, Glucose metabolism, Glycogen biosynthesis, Glycogen metabolism, Sugar transport, Translation regulation, Transport" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Diabetes mellitus, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Minor Salivary Gland - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004204, HPA064521, HPA069327, CAB080295" Uncertain Enhanced Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 34: B-cells - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 48: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 89: Adipocytes - Lipid metabolism" 23 "Vesicles, Cytosol" Nucleoplasm "CAB004204: , CAB080295: , HPA064521: , HPA069327: " "unprognostic (3.37e-2)" "unprognostic (2.90e-1)" "unprognostic (4.26e-1)" "unprognostic (7.79e-2)" "unprognostic (2.86e-1)" "unprognostic (1.61e-1)" "unprognostic (2.09e-1)" "unprognostic (3.96e-1)" "unprognostic (2.84e-2)" "unprognostic (2.65e-1)" "unprognostic (2.94e-3)" "unprognostic (8.43e-2)" "unprognostic (7.98e-2)" "unprognostic (3.32e-1)" "unprognostic (2.73e-1)" "potential prognostic unfavorable (9.97e-5)" "unprognostic (5.79e-2)" "unprognostic (3.35e-2)" "unprognostic (3.06e-1)" "unprognostic (5.13e-3)" "unprognostic (1.41e-1)" "unprognostic (5.21e-2)" "unprognostic (3.59e-2)" "unprognostic (3.16e-1)" "unprognostic (2.34e-2)" "unprognostic (2.13e-2)" "unprognostic (2.79e-2)" "unprognostic (4.20e-1)" "unprognostic (2.39e-1)" "unprognostic (1.18e-1)" "unprognostic (1.05e-2)" AKT3 "PKBG, PRKBG, RAC-gamma" ENSG00000117020 "AKT serine/threonine kinase 3" Q9Y243 1 243488233-243851079 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 670.6;Bergmann glia: 1045.5;Brain excitatory neurons: 759.9;Brain inhibitory neurons: 518.7;Choroid plexus epithelial cells: 417.9;Distal convoluted tubule cells: 294.1;Ependymal cells: 596.4;Microglia: 765.1;Oligodendrocyte progenitor cells: 830.4;Oligodendrocytes: 572.8;Other brain neurons: 455.8;Podocytes: 963.7;Renal collecting duct intercalated cells: 364.9;Renal collecting duct principal cells: 521.8;Renal connecting tubule cells: 404.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013090, HPA026441" Approved Supported "Nucleoplasm,Golgi apparatus,Plasma membrane,Primary cilium,Basal body,Cytosol" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 34: Non-specific - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 102: Non-specific - Mixed function" 10 "Nucleoplasm, Golgi apparatus, Cytosol" "Plasma membrane, Primary cilium, Basal body" "CAB013090: , HPA026441: " "unprognostic (2.83e-1)" "unprognostic (2.78e-1)" "unprognostic (1.55e-1)" "unprognostic (1.52e-1)" "unprognostic (2.05e-2)" "unprognostic (8.46e-2)" "unprognostic (4.14e-2)" "unprognostic (1.52e-3)" "unprognostic (1.36e-1)" "unprognostic (2.21e-1)" "validated prognostic favorable (3.00e-6)" "validated prognostic favorable (1.34e-4)" "unprognostic (1.81e-2)" "unprognostic (1.50e-1)" "unprognostic (2.55e-1)" "unprognostic (2.83e-1)" "unprognostic (2.46e-1)" "unprognostic (2.93e-1)" "unprognostic (1.06e-1)" "unprognostic (2.03e-1)" "unprognostic (6.55e-3)" "unprognostic (6.08e-3)" "unprognostic (4.56e-2)" "unprognostic (2.04e-1)" "unprognostic (1.39e-1)" "unprognostic (4.57e-3)" "unprognostic (4.06e-1)" "potential prognostic unfavorable (3.15e-4)" "unprognostic (9.84e-2)" "unprognostic (2.56e-1)" "unprognostic (1.96e-2)" AKTIP "FLJ13258, FTS" ENSG00000166971 "AKT interacting protein" Q9H8T0 16 53491040-53504411 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 225.1;Esophageal apical cells: 129.8;Late spermatids: 494.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041794, HPA046300" Approved Approved "Nucleoli,Golgi apparatus,Plasma membrane,Basal body,Cytosol" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 28 "Nucleoli, Golgi apparatus, Basal body" "Plasma membrane, Cytosol" "HPA041794: , HPA046300: " "unprognostic (1.48e-2)" "unprognostic (5.56e-2)" "unprognostic (1.46e-1)" "unprognostic (3.27e-2)" "unprognostic (1.24e-1)" "unprognostic (2.60e-2)" "unprognostic (2.15e-1)" "unprognostic (9.78e-2)" "unprognostic (1.16e-1)" "unprognostic (1.17e-1)" "potential prognostic favorable (9.77e-14)" "unprognostic (3.15e-3)" "unprognostic (1.14e-1)" "unprognostic (3.30e-2)" "unprognostic (1.04e-3)" "unprognostic (9.81e-3)" "unprognostic (1.83e-1)" "unprognostic (1.85e-2)" "unprognostic (2.28e-1)" "unprognostic (1.15e-1)" "unprognostic (4.42e-2)" "unprognostic (6.33e-3)" "unprognostic (1.00e-1)" "unprognostic (3.61e-1)" "unprognostic (1.71e-1)" "unprognostic (3.04e-2)" "unprognostic (4.29e-1)" "unprognostic (7.61e-3)" "unprognostic (1.63e-1)" "unprognostic (2.43e-1)" "unprognostic (8.15e-2)" ALAD "ALADH, PBGS" ENSG00000148218 "Aminolevulinate dehydratase" P13716 9 113386312-113401290 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Heme biosynthesis, Porphyrin biosynthesis" "Allosteric enzyme, Lyase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 196.1" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 172.2;Erythrocyte progenitors: 310.9;Esophageal apical cells: 109.6;Esophageal suprabasal cells: 103.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Stomach - Parietal cells, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021023, HPA022124" Enhanced Approved Cytosol NA NA 17000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 76: Non-specific - Metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 1 Cytosol "HPA021023: , HPA022124: " "unprognostic (6.93e-2)" "unprognostic (4.58e-2)" "unprognostic (6.30e-2)" "unprognostic (2.62e-1)" "unprognostic (1.01e-3)" "potential prognostic unfavorable (7.44e-5)" "unprognostic (7.13e-2)" "unprognostic (2.36e-1)" "unprognostic (7.97e-2)" "unprognostic (2.49e-1)" "validated prognostic favorable (4.80e-10)" "validated prognostic favorable (2.67e-4)" "unprognostic (3.39e-2)" "validated prognostic favorable (3.62e-4)" "validated prognostic favorable (1.72e-5)" "unprognostic (6.19e-3)" "unprognostic (1.94e-1)" "unprognostic (3.44e-2)" "potential prognostic favorable (5.01e-4)" "unprognostic (5.76e-2)" "unprognostic (2.68e-1)" "unprognostic (1.45e-1)" "unprognostic (1.89e-1)" "unprognostic (3.52e-2)" "unprognostic (1.88e-1)" "unprognostic (3.69e-3)" "unprognostic (2.57e-1)" "unprognostic (5.72e-2)" "unprognostic (8.66e-2)" "unprognostic (2.18e-1)" "unprognostic (3.71e-2)" ALAS1 "ALAS, ALAS-H, ALAS3" ENSG00000023330 "5'-aminolevulinate synthase 1" P13196 3 52198086-52214327 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Heme biosynthesis" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 697.4;liver: 513.2" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 534.3;Esophageal apical cells: 140.4;Hepatocytes: 282.3;Syncytiotrophoblasts: 420.3;Urothelial cells: 168.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 234.4" "Lineage enriched" "Detected in all" 5 "granulocytes: 234.4" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017498, HPA035860" Enhanced Supported Nucleoplasm,Mitochondria NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 76: Non-specific - Metabolism" "Cluster 12: Non-specific - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 18: Adrenal cortex cells - Steroidogensis" 44 Mitochondria Nucleoplasm "CAB017498: , HPA035860: " "potential prognostic favorable (3.69e-4)" "unprognostic (2.07e-1)" "unprognostic (4.36e-1)" "unprognostic (5.86e-2)" "unprognostic (9.93e-3)" "unprognostic (2.01e-1)" "unprognostic (1.23e-1)" "unprognostic (1.91e-1)" "unprognostic (1.49e-1)" "unprognostic (1.57e-2)" "unprognostic (1.76e-3)" "unprognostic (5.40e-2)" "unprognostic (8.32e-3)" "potential prognostic favorable (6.05e-5)" "unprognostic (1.34e-2)" "unprognostic (8.95e-2)" "unprognostic (5.16e-2)" "unprognostic (9.99e-2)" "unprognostic (9.54e-2)" "unprognostic (9.05e-3)" "unprognostic (1.51e-1)" "unprognostic (3.54e-2)" "unprognostic (8.88e-2)" "unprognostic (1.20e-1)" "unprognostic (1.26e-1)" "unprognostic (5.75e-2)" "unprognostic (1.55e-1)" "unprognostic (9.16e-2)" "unprognostic (3.08e-2)" "unprognostic (2.41e-1)" "unprognostic (9.73e-2)" ALAS2 "ALAS-E, ASB" ENSG00000158578 "5'-aminolevulinate synthase 2" P22557 X 55009055-55030977 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Heme biosynthesis" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "bone marrow: 571.0" "Cell type enriched" "Detected in some" 4 "Erythrocytes: 1762.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney Renal Papillary Cell Carcinoma (TCGA): 1.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "plasmacytoid DC: 1.6" "Lineage enriched" "Detected in single" 6 "dendritic cells: 1.6" "Cancer enriched" "Detected in single" 55 "Leukemia: 33.7" "Liver - Erythroid cells, Pituitary gland - Neutrophils, Spleen - Erythrocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 15: Bone marrow - Innate immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 47: Leukemia - Hemostasis" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 1 "potential prognostic favorable (4.57e-5)" "unprognostic (2.47e-1)" "unprognostic (7.60e-2)" ALB ENSG00000163631 Albumin P02768 4 73397114-73421482 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 134 "liver: 198523.8" "Cell type enriched" "Detected in some" 4 "Hepatocytes: 81391.2" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in many" 407 "Liver Hepatocellular Carcinoma (TCGA): 38403.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 24 "liver cancer: 1846.4" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB006262, HPA031024, HPA031025" Enhanced Approved "Endoplasmic reticulum,Golgi apparatus" "Secreted to blood" Transport NA NA 40000000000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 33: Neurons - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 93: Hepatocytes - Bile production & excretion" 27 "Endoplasmic reticulum, Golgi apparatus" "CAB006262: , HPA031024: , HPA031025: " "unprognostic (6.95e-3)" "unprognostic (2.77e-1)" "unprognostic (7.30e-2)" "unprognostic (6.46e-2)" "validated prognostic favorable (3.80e-4)" "validated prognostic favorable (3.74e-4)" "unprognostic (2.18e-1)" "unprognostic (1.32e-2)" "unprognostic (2.17e-3)" "unprognostic (1.17e-2)" "unprognostic (7.56e-2)" "unprognostic (2.47e-1)" "unprognostic (3.17e-1)" "unprognostic (4.51e-2)" "potential prognostic unfavorable (8.71e-4)" "unprognostic (3.58e-2)" "unprognostic (2.35e-1)" "unprognostic (3.31e-1)" "unprognostic (1.95e-3)" "unprognostic (5.35e-2)" "unprognostic (1.69e-3)" "unprognostic (2.59e-1)" ALCAM "CD166, MEMD" ENSG00000170017 "Activated leukocyte cell adhesion molecule" Q13740 3 105366909-105576900 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Adaptive immunity, Cell adhesion, Immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "parathyroid gland: 412.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 1172.5;Conjunctival goblet cells: 1484.5;Endometrial ciliated cells: 1260.6;Endometrial glandular cells: 1692.7;Endometrial luminal cells: 1651.0;Respiratory ciliated cells: 1131.4;Respiratory deuterosomal cells: 1650.3;Respiratory secretory cells: 1807.6;Transitional alveolar cells: 1377.2" "Cell type enhanced" "Detected in all" "mammillary body: 2102.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 29.6" "Lineage enriched" "Detected in many" 6 "dendritic cells: 29.6" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Colon - Enteric glia cells, Liver - Hepatocytes, Pituitary gland - Lactotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002148, HPA010926" Enhanced Uncertain Vesicles "Secreted to blood" Immunity NA NA 60000000 110000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 13 Vesicles "CAB002148: , HPA010926: " "unprognostic (1.05e-1)" "unprognostic (2.12e-1)" "unprognostic (4.59e-2)" "unprognostic (3.76e-1)" "unprognostic (1.05e-1)" "unprognostic (1.00e-1)" "unprognostic (7.08e-3)" "potential prognostic favorable (6.10e-4)" "unprognostic (3.17e-2)" "unprognostic (1.93e-2)" "potential prognostic favorable (7.99e-7)" "unprognostic (2.59e-3)" "unprognostic (1.72e-1)" "potential prognostic unfavorable (9.77e-4)" "unprognostic (2.25e-1)" "unprognostic (1.73e-2)" "unprognostic (5.35e-2)" "unprognostic (1.86e-1)" "unprognostic (4.19e-2)" "unprognostic (2.14e-1)" "unprognostic (1.68e-2)" "unprognostic (2.70e-1)" "unprognostic (3.29e-2)" "unprognostic (1.68e-1)" "unprognostic (3.51e-1)" "unprognostic (2.68e-1)" "unprognostic (4.69e-2)" "unprognostic (2.71e-1)" "unprognostic (1.90e-2)" "unprognostic (7.77e-3)" "unprognostic (9.45e-2)" ALDH16A1 MGC10204 ENSG00000161618 "Aldehyde dehydrogenase 16 family member A1" Q8IZ83 19 49453225-49471050 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Enterocytes: 23.8;Hofbauer cells: 20.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059488 Approved NA NA 720000 "Cluster 29: Non-specific - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 4: Non-specific - Transcription" "Cluster 65: Non-specific - Cell growth & division" 12 "HPA059488: " "unprognostic (3.45e-1)" "unprognostic (3.51e-2)" "unprognostic (1.58e-1)" "unprognostic (7.03e-2)" "unprognostic (1.82e-1)" "unprognostic (1.41e-1)" "unprognostic (3.35e-1)" "unprognostic (1.42e-1)" "unprognostic (3.08e-3)" "unprognostic (1.56e-1)" "unprognostic (5.93e-2)" "unprognostic (9.97e-2)" "unprognostic (4.56e-2)" "unprognostic (1.47e-1)" "unprognostic (2.09e-3)" "unprognostic (4.81e-2)" "unprognostic (1.92e-1)" "unprognostic (2.52e-1)" "unprognostic (3.05e-1)" "unprognostic (1.33e-1)" "unprognostic (2.38e-1)" "unprognostic (5.54e-2)" "unprognostic (1.50e-1)" "unprognostic (6.73e-2)" "unprognostic (3.32e-1)" "unprognostic (3.41e-1)" "unprognostic (1.12e-1)" "unprognostic (4.21e-2)" "unprognostic (2.56e-1)" "unprognostic (6.48e-3)" "unprognostic (7.80e-2)" ALDH18A1 "GSAS, P5CS, PYCS, SPG9" ENSG00000059573 "Aldehyde dehydrogenase 18 family member A1" P54886 10 95605941-95656711 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Proline biosynthesis" "Kinase, Multifunctional enzyme, Oxidoreductase, Transferase" "Disease variant, Hereditary spastic paraplegia, Intellectual disability, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 113.1" "Cell type enhanced" "Detected in many" "Salivary acinar cells: 153.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008333, HPA012604" Approved Enhanced Mitochondria NA NA 70000 "Cluster 24: Non-specific - Transcription" "Cluster 60: Stomach - Digestion" "Cluster 44: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 25 Mitochondria "HPA008333: , HPA012604: " "unprognostic (7.54e-2)" "potential prognostic unfavorable (5.36e-4)" "unprognostic (2.14e-1)" "unprognostic (1.02e-1)" "unprognostic (1.36e-1)" "unprognostic (5.49e-2)" "unprognostic (2.23e-2)" "potential prognostic favorable (4.32e-4)" "unprognostic (5.93e-2)" "unprognostic (7.26e-2)" "unprognostic (1.21e-3)" "potential prognostic unfavorable (8.73e-4)" "unprognostic (1.11e-2)" "potential prognostic unfavorable (4.91e-4)" "unprognostic (8.93e-3)" "unprognostic (4.22e-2)" "potential prognostic unfavorable (8.95e-4)" "unprognostic (2.82e-2)" "unprognostic (4.17e-2)" "unprognostic (3.09e-1)" "unprognostic (3.48e-2)" "unprognostic (4.67e-2)" "unprognostic (5.74e-3)" "unprognostic (1.83e-1)" "unprognostic (1.52e-1)" "unprognostic (9.56e-2)" "unprognostic (3.79e-2)" "unprognostic (2.09e-3)" "unprognostic (1.18e-1)" "potential prognostic unfavorable (7.13e-4)" "unprognostic (1.88e-2)" ALDH1A1 "ALDH1, PUMB1, RALDH1" ENSG00000165092 "Aldehyde dehydrogenase 1 family member A1" P00352 9 72900671-73080442 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 1403.3" "Cell type enhanced" "Detected in many" "Bergmann glia: 1199.3;Conjunctival goblet cells: 654.4;Hepatocytes: 876.5;Pancreatic islet cells: 684.9;Parietal cells: 2970.1;Respiratory ciliated cells: 714.3;Respiratory deuterosomal cells: 906.0;Respiratory secretory cells: 1138.0" "Group enriched" "Detected in many" 5 "astrocyte: 398.2;Bergmann glia: 1353.3" "Cancer enhanced" "Detected in all" "Kidney Renal Papillary Cell Carcinoma (TCGA): 745.7;Liver Hepatocellular Carcinoma (TCGA): 682.5" "Region enhanced" "Detected in all" "midbrain: 738.6" "Immune cell enriched" "Detected in many" 6 "classical monocyte: 87.5" "Lineage enriched" "Detected in many" 33 "monocytes: 87.5" "Cancer enhanced" "Detected in many" "liver cancer: 1023.3;Rhabdoid: 959.5;Sarcoma: 855.7" "Breast - Fibroblasts, Liver - Hepatocytes, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_2, Stomach - Parietal cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 6 "midbrain: 494.1" "HPA002123, CAB020690" Enhanced Approved Enhanced Cytosol NA NA 50000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 25: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 17 Cytosol "CAB020690: , HPA002123: " "unprognostic (6.73e-2)" "unprognostic (3.35e-2)" "unprognostic (4.78e-1)" "potential prognostic favorable (2.97e-4)" "unprognostic (2.09e-1)" "unprognostic (2.41e-1)" "unprognostic (1.99e-2)" "unprognostic (1.55e-1)" "unprognostic (1.47e-1)" "unprognostic (7.90e-2)" "potential prognostic favorable (4.89e-7)" "unprognostic (2.12e-1)" "unprognostic (5.02e-2)" "unprognostic (3.97e-2)" "unprognostic (9.15e-3)" "unprognostic (5.48e-2)" "unprognostic (2.19e-2)" "unprognostic (3.54e-3)" "unprognostic (1.01e-1)" "unprognostic (1.59e-1)" "unprognostic (1.22e-1)" "unprognostic (3.22e-2)" "unprognostic (1.55e-2)" "unprognostic (4.32e-1)" "unprognostic (3.81e-2)" "unprognostic (1.43e-2)" "unprognostic (3.11e-2)" "unprognostic (1.95e-1)" "unprognostic (2.36e-1)" "unprognostic (1.19e-2)" "unprognostic (2.25e-1)" ALDH1A2 RALDH2 ENSG00000128918 "Aldehyde dehydrogenase 1 family member A2" O94788 15 57953424-58497866 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 76.9;fallopian tube: 70.1" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 394.1;Endometrial stromal cells: 494.1;Epicardial cells: 1000.6;Hepatocytes: 403.1;Mesothelial cells: 344.1;Müller glia: 281.2;Neutrophils: 1959.1;Pituitary stem cells: 841.5;Prostatic club cells: 337.8" "Group enriched" "Detected in many" 4 "fibroblast: 435.4;hippocampal dentate gyrus: 1054.7" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 33.1" "Region enhanced" "Detected in all" "cerebral cortex: 27.1" "Immune cell enriched" "Detected in some" 15 "neutrophil: 32.8" "Lineage enriched" "Detected in single" 62 "granulocytes: 32.8" "Cancer enhanced" "Detected in many" "Leukemia: 31.9;liver cancer: 16.2" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal cortex cells, Pituitary gland - Lactotropes, Skeletal muscle - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA010022 Approved NA NA 350000 "Cluster 35: Neutrophils - Protein binding" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 29: Forebrain - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 14 "HPA010022: " "unprognostic (6.87e-2)" "unprognostic (2.59e-2)" "unprognostic (1.09e-1)" "unprognostic (1.48e-1)" "unprognostic (9.69e-2)" "unprognostic (1.66e-3)" "unprognostic (1.28e-1)" "unprognostic (5.23e-2)" "unprognostic (1.53e-1)" "unprognostic (7.03e-3)" "unprognostic (3.74e-3)" "unprognostic (9.17e-2)" "unprognostic (8.60e-2)" "unprognostic (1.41e-2)" "unprognostic (3.65e-2)" "unprognostic (1.68e-1)" "unprognostic (2.79e-2)" "unprognostic (4.61e-1)" "potential prognostic unfavorable (8.11e-4)" "unprognostic (2.02e-1)" "unprognostic (1.77e-1)" "unprognostic (8.74e-2)" "unprognostic (2.08e-1)" "unprognostic (2.97e-2)" "unprognostic (1.21e-1)" "unprognostic (1.28e-2)" "unprognostic (1.84e-1)" "unprognostic (2.22e-2)" ALDH1A3 "ALDH6, RALDH3" ENSG00000184254 "Aldehyde dehydrogenase 1 family member A3" P47895 15 100877714-100916626 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 126.3;urinary bladder: 116.7" "Cell type enhanced" "Detected in many" "Breast lactating cells: 208.9;Breast secretory cells: 204.5;Decidual stromal cells: 204.0;Endometrial stromal cells: 231.1;Epicardial cells: 334.3;Lacrimal acinar cells: 469.2;Leydig cells: 263.5;Mesothelial cells: 219.2;Ocular epithelial cells: 381.7;Prostatic glandular cells: 215.7;Retinal pigment epithelial cells: 315.5;Salivary acinar cells: 408.7;Salivary basal cells: 273.3;Salivary duct cells: 670.9;Salivary ionocytes: 226.5;Urothelial cells: 467.8" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 27.0;fibroblast: 24.1;oligodendrocyte precursor cell: 37.8" "Group enriched" "Detected in all" 6 "Prostate Adenocarcinoma (TCGA): 310.1;Skin Cutaneous Melanoma (TCGA): 78.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "pancreatic cancer: 420.2" "Adipose subcutaneous - Adipose progenitor cells, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Somatotropes, Prostate - Prostate glandular cells" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "olfactory bulb: 6.0;spinal cord: 20.7" "HPA046271, HPA064749" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 2 Nucleoplasm Cytosol "HPA046271: , HPA064749: " "unprognostic (1.60e-1)" "unprognostic (2.72e-1)" "unprognostic (2.55e-1)" "unprognostic (5.59e-2)" "potential prognostic unfavorable (3.91e-4)" "unprognostic (3.87e-3)" "unprognostic (1.31e-2)" "unprognostic (9.30e-3)" "unprognostic (1.37e-1)" "unprognostic (8.38e-2)" "unprognostic (2.84e-3)" "unprognostic (2.39e-1)" "unprognostic (1.83e-3)" "unprognostic (1.32e-1)" "unprognostic (1.61e-3)" "unprognostic (1.12e-1)" "unprognostic (1.42e-3)" "unprognostic (6.41e-2)" "unprognostic (1.55e-3)" "unprognostic (1.23e-2)" "potential prognostic unfavorable (3.94e-5)" "unprognostic (8.92e-2)" "unprognostic (9.34e-2)" "unprognostic (2.54e-1)" "unprognostic (9.11e-2)" "unprognostic (1.10e-2)" "unprognostic (2.63e-1)" "unprognostic (2.38e-2)" "unprognostic (9.95e-2)" "unprognostic (2.04e-1)" "unprognostic (2.90e-1)" ALDH1B1 "ALDH5, ALDHX" ENSG00000137124 "Aldehyde dehydrogenase 1 family member B1" P30837 9 38392702-38398661 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 138.0;liver: 161.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 93.1;Enteric stem cells: 139.6;Enteric transient amplifying cells: 51.5;Extravillous trophoblasts: 61.1;Hepatic stellate cells: 45.2;Hepatocytes: 156.0;Paneth cells: 123.8;Smooth muscle cells: 184.0" "Cell type enhanced" "Detected in many" "vascular associated smooth muscle cell: 7.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Smooth muscle cells, Skin - Smooth muscle cells, Spleen - Smooth muscle cells, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021037, HPA077080" Enhanced Supported Mitochondria NA NA 320000 "Cluster 33: Non-specific - ATP binding" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 45: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 62: Smooth muscle cells - Muscle contraction" 19 Mitochondria "HPA021037: , HPA077080: " "unprognostic (3.51e-2)" "unprognostic (2.55e-1)" "unprognostic (1.77e-1)" "unprognostic (4.37e-3)" "unprognostic (2.13e-2)" "unprognostic (1.72e-1)" "unprognostic (4.77e-2)" "unprognostic (1.08e-1)" "unprognostic (1.47e-3)" "unprognostic (1.56e-1)" "potential prognostic favorable (4.96e-5)" "unprognostic (6.57e-3)" "unprognostic (1.34e-1)" "unprognostic (2.55e-2)" "unprognostic (2.67e-3)" "unprognostic (1.37e-1)" "potential prognostic unfavorable (1.93e-4)" "unprognostic (6.80e-2)" "unprognostic (1.33e-1)" "unprognostic (1.09e-3)" "unprognostic (6.23e-2)" "unprognostic (3.43e-1)" "unprognostic (2.87e-3)" "unprognostic (3.76e-1)" "unprognostic (2.37e-1)" "unprognostic (7.16e-2)" "unprognostic (5.16e-2)" "unprognostic (3.88e-2)" "unprognostic (1.52e-1)" "potential prognostic unfavorable (2.64e-6)" "unprognostic (8.27e-3)" ALDH1L1 "10-fTHF, FDH, FTHFD" ENSG00000144908 "Aldehyde dehydrogenase 1 family member L1" O75891 3 126103562-126197994 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "One-carbon metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 345.7" "Cell type enhanced" "Detected in many" "Adipocytes: 183.8;Astrocytes: 167.1;Bergmann glia: 262.8;Breast lactating cells: 199.5;Hepatocytes: 1030.6;Lacrimal acinar cells: 176.6;Proximal tubule cells: 316.1;Salivary acinar cells: 180.8" "Group enriched" "Detected in many" 5 "astrocyte: 192.7;Bergmann glia: 281.3" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 224.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder cancer: 16.3" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036900, HPA050139" Enhanced Supported Supported Cytosol No No 4500000 "Cluster 16: Liver & Kidney - Metabolism" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 93: Hepatocytes - Bile production & excretion" 5 Cytosol "HPA036900: , HPA050139: " "unprognostic (3.21e-1)" "unprognostic (1.07e-1)" "unprognostic (3.45e-3)" "unprognostic (2.50e-1)" "unprognostic (7.67e-2)" "unprognostic (1.86e-1)" "unprognostic (2.12e-1)" "unprognostic (4.33e-3)" "unprognostic (1.12e-1)" "unprognostic (4.06e-1)" "potential prognostic favorable (2.78e-7)" "unprognostic (3.44e-3)" "unprognostic (2.60e-2)" "unprognostic (1.08e-1)" "unprognostic (3.01e-2)" "unprognostic (3.86e-1)" "unprognostic (3.78e-1)" "unprognostic (5.09e-2)" "unprognostic (4.64e-2)" "unprognostic (8.55e-2)" "unprognostic (1.25e-2)" "unprognostic (1.90e-3)" "unprognostic (1.01e-1)" "unprognostic (9.81e-2)" "unprognostic (1.90e-1)" "unprognostic (1.64e-3)" "unprognostic (1.43e-1)" "unprognostic (3.10e-2)" "unprognostic (2.14e-1)" "potential prognostic unfavorable (8.79e-4)" "unprognostic (1.76e-1)" ALDH1L2 "FLJ38508, mtFDH" ENSG00000136010 "Aldehyde dehydrogenase 1 family member L2" Q3SY69 12 105019784-105107643 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "One-carbon metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "pancreas: 38.3;salivary gland: 12.2" "Cell type enhanced" "Detected in many" "Fibro-adipogenic progenitors: 70.1;Gonadotrophs: 64.8;Pancreatic acinar cells: 107.4;Pituitary stem cells: 61.8;Plasma cells: 74.7;Retinal ganglion cells: 46.4;Salivary acinar cells: 43.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 39.5" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Kidney - Fibroblasts, Minor Salivary Gland - Minor salivary glandular cells, Stomach - Chief cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039481, HPA059282" Approved Supported Mitochondria No No "Cluster 8: Pancreas - Proteolysis" "Cluster 25: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 44: Plasma cells - Antibody production & secretion" 4 Mitochondria "HPA039481: , HPA059282: " "unprognostic (1.58e-3)" "unprognostic (2.23e-1)" "unprognostic (1.17e-1)" "unprognostic (1.66e-1)" "unprognostic (1.82e-1)" "unprognostic (1.51e-1)" "unprognostic (9.10e-2)" "unprognostic (5.31e-2)" "unprognostic (7.96e-2)" "unprognostic (1.37e-3)" "unprognostic (4.56e-2)" "unprognostic (1.80e-1)" "unprognostic (4.26e-2)" "unprognostic (4.98e-2)" "unprognostic (2.59e-1)" "unprognostic (1.02e-1)" "unprognostic (1.43e-3)" "unprognostic (1.18e-1)" "unprognostic (1.75e-1)" "unprognostic (6.91e-3)" "unprognostic (4.13e-2)" "unprognostic (2.56e-1)" "unprognostic (1.45e-2)" "unprognostic (1.38e-1)" "unprognostic (9.37e-2)" ALDH2 ENSG00000111275 "Aldehyde dehydrogenase 2 family member" P05091 12 111766887-111817532 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Disease variant, Dwarfism, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 801.4" "Cell type enhanced" "Detected in many" "Hepatocytes: 984.1;Kupffer cells: 442.8;Respiratory secretory cells: 446.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 212.7;myeloid DC: 213.7" "Group enriched" "Detected in many" 4 "dendritic cells: 213.7;monocytes: 212.7" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Spleen - Fibroblasts_2, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051065 Approved NA NA 3200000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 12 "HPA051065: " "unprognostic (4.33e-2)" "unprognostic (1.97e-2)" "unprognostic (2.80e-1)" "unprognostic (8.86e-3)" "potential prognostic favorable (8.20e-4)" "unprognostic (1.16e-2)" "unprognostic (8.93e-2)" "unprognostic (1.21e-1)" "unprognostic (5.24e-3)" "unprognostic (2.57e-2)" "unprognostic (1.15e-3)" "unprognostic (7.74e-3)" "potential prognostic favorable (1.56e-4)" "validated prognostic favorable (4.95e-7)" "validated prognostic favorable (3.12e-4)" "unprognostic (1.39e-3)" "unprognostic (3.69e-2)" "unprognostic (2.62e-2)" "unprognostic (2.36e-1)" "unprognostic (1.04e-1)" "unprognostic (1.45e-1)" "unprognostic (1.60e-2)" "potential prognostic favorable (1.61e-4)" "unprognostic (9.65e-2)" "unprognostic (1.28e-1)" "unprognostic (9.83e-2)" "unprognostic (2.39e-1)" "unprognostic (1.38e-1)" "unprognostic (1.54e-1)" "unprognostic (1.26e-2)" "unprognostic (2.86e-2)" ALDH3A1 ALDH3 ENSG00000108602 "Aldehyde dehydrogenase 3 family member A1" P30838 17 19737984-19748943 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 504.2;salivary gland: 117.1;stomach 1: 212.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 427.0;Conjunctival goblet cells: 1071.8;Esophageal apical cells: 1402.6;Esophageal basal cells: 645.5;Esophageal suprabasal cells: 1716.4;Ocular epithelial cells: 2180.5;Respiratory basal cells: 441.1;Respiratory secretory cells: 387.4;Suprabasal keratinocytes: 751.9" "Group enriched" "Detected in some" 15 "choroid plexus epithelial cell: 10.1;ependymal cell: 18.6" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 220.0;Lung Squamous Cell Carcinoma (TCGA): 332.4" "Region enriched" "Detected in many" 8 "choroid plexus: 35.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Gallbladder cancer: 3329.2" "Adipose visceral - Mesothelial cells, Lung - Respiratory ciliated cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB045957, HPA051150, HPA063783" Enhanced Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" No No 70000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 100: Stratified epithelial cells - Barrier functions" 27 "Plasma membrane, Cytosol" "Nucleoplasm, Vesicles" "CAB045957: , HPA051150: , HPA063783: " "unprognostic (3.66e-2)" "potential prognostic favorable (5.12e-5)" "unprognostic (4.35e-2)" "unprognostic (1.86e-2)" "unprognostic (4.51e-2)" "unprognostic (1.12e-1)" "unprognostic (6.93e-3)" "potential prognostic favorable (8.42e-5)" "unprognostic (8.26e-3)" "unprognostic (1.94e-1)" "unprognostic (1.67e-3)" "unprognostic (2.90e-1)" "unprognostic (1.75e-1)" "unprognostic (2.74e-1)" "unprognostic (2.01e-3)" "unprognostic (5.16e-2)" "unprognostic (2.76e-1)" "unprognostic (3.34e-2)" "unprognostic (7.25e-2)" "unprognostic (3.08e-3)" "unprognostic (6.54e-3)" "unprognostic (5.69e-2)" "unprognostic (1.96e-1)" "unprognostic (1.02e-3)" "unprognostic (1.24e-1)" "unprognostic (8.37e-2)" "unprognostic (3.13e-2)" "unprognostic (1.06e-1)" ALDH3A2 "ALDH10, FALDH, SLS" ENSG00000072210 "Aldehyde dehydrogenase 3 family member A2" P51648 17 19648136-19685760 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant, Ichthyosis, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 269.4" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 277.6;Alveolar cells type 1: 297.2;Esophageal apical cells: 341.0;Esophageal basal cells: 250.4;Esophageal suprabasal cells: 252.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Lung - Alveolar cells type 1, Skin - Keratinocyte (other), Testis - Leydig cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014769, CAB020692" Enhanced Approved "Endoplasmic reticulum,Cytosol" NA NA 67000 "Cluster 33: Non-specific - ATP binding" "Cluster 76: Non-specific - Metabolism" "Cluster 36: Choroid plexus - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 26: Keratinocytes - Keratinization" 21 "Endoplasmic reticulum, Cytosol" "CAB020692: , HPA014769: " "unprognostic (1.40e-1)" "unprognostic (4.91e-2)" "unprognostic (1.57e-2)" "unprognostic (2.64e-1)" "unprognostic (2.03e-2)" "unprognostic (8.42e-2)" "unprognostic (3.76e-1)" "unprognostic (8.54e-2)" "unprognostic (1.79e-1)" "unprognostic (1.24e-2)" "validated prognostic favorable (1.15e-10)" "validated prognostic favorable (4.77e-4)" "unprognostic (2.44e-3)" "unprognostic (1.86e-1)" "unprognostic (2.67e-2)" "unprognostic (8.65e-2)" "unprognostic (8.34e-2)" "unprognostic (1.73e-1)" "unprognostic (1.31e-1)" "unprognostic (2.13e-2)" "unprognostic (1.55e-1)" "unprognostic (1.40e-1)" "unprognostic (1.23e-1)" "unprognostic (5.95e-2)" "unprognostic (1.81e-1)" "unprognostic (4.71e-2)" "unprognostic (5.18e-2)" "unprognostic (2.61e-3)" "unprognostic (2.02e-1)" "unprognostic (1.69e-1)" "potential prognostic favorable (2.59e-4)" ALDH3B1 ALDH7 ENSG00000006534 "Aldehyde dehydrogenase 3 family member B1" P43353 11 68008578-68029282 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 77.6;Endometrial ciliated cells: 67.2;Esophageal apical cells: 123.0;Fallopian tube ciliated cells: 155.0;Kupffer cells: 60.5;Neutrophil progenitors: 134.3;Respiratory ciliated cells: 345.5;Transitional alveolar cells: 60.6" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 10.8;choroid plexus epithelial cell: 7.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 157.1" "Group enriched" "Detected in many" 10 "dendritic cells: 63.6;granulocytes: 157.1;monocytes: 119.2" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adipose visceral - Mesothelial cells" "Low region specificity" "Detected in all" HPA038525 Uncertain NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 7: Liver cancer - Metabolism" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 34 "HPA038525: " "unprognostic (4.82e-2)" "unprognostic (2.58e-1)" "unprognostic (2.10e-1)" "unprognostic (2.65e-1)" "unprognostic (6.84e-2)" "unprognostic (4.41e-3)" "unprognostic (3.87e-3)" "unprognostic (2.35e-2)" "unprognostic (4.70e-2)" "unprognostic (2.40e-2)" "unprognostic (1.31e-1)" "unprognostic (1.29e-2)" "unprognostic (1.56e-1)" "unprognostic (5.52e-3)" "unprognostic (8.65e-3)" "unprognostic (1.68e-1)" "unprognostic (3.20e-2)" "unprognostic (2.02e-3)" "unprognostic (1.75e-1)" "unprognostic (9.16e-2)" "unprognostic (2.84e-2)" "potential prognostic unfavorable (8.36e-4)" "unprognostic (5.97e-2)" "unprognostic (4.20e-2)" "unprognostic (1.92e-2)" "unprognostic (1.11e-1)" "unprognostic (2.53e-1)" "unprognostic (1.15e-1)" "unprognostic (1.30e-2)" "unprognostic (9.72e-3)" "unprognostic (1.13e-1)" ALDH3B2 ALDH8 ENSG00000132746 "Aldehyde dehydrogenase 3 family member B2" P48448 11 67662155-67681224 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 68.4;esophagus: 157.7;skin 1: 126.8" "Group enriched" "Detected in some" 4 "Esophageal apical cells: 372.7;Esophageal suprabasal cells: 260.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 81.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 7 "breast cancer: 104.9" "Breast - Breast glandular cells, Breast - Breast glandular cells" "Region enriched" "Detected in single" 8 "olfactory bulb: 1.0" "Not detected" "Not detected" HPA045132 Approved NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 27: Breast cancer - Unknown function" "Cluster 85: Squamous epithelial cells - Keratinization" 14 "HPA045132: " "unprognostic (2.72e-1)" "unprognostic (2.04e-1)" "unprognostic (9.65e-2)" "unprognostic (9.11e-3)" "unprognostic (1.78e-1)" "unprognostic (2.05e-1)" "unprognostic (2.35e-1)" "unprognostic (1.42e-1)" "unprognostic (1.41e-1)" "unprognostic (1.99e-2)" "unprognostic (4.68e-2)" "unprognostic (8.00e-2)" "unprognostic (2.77e-2)" "unprognostic (3.55e-1)" "unprognostic (1.28e-1)" "unprognostic (3.88e-2)" "unprognostic (3.97e-2)" "unprognostic (1.15e-1)" "unprognostic (8.75e-2)" "unprognostic (2.26e-3)" "unprognostic (2.46e-2)" "unprognostic (4.37e-2)" "unprognostic (7.22e-2)" ALDH4A1 "ALDH4, P5CDh" ENSG00000159423 "Aldehyde dehydrogenase 4 family member A1" P30038 1 18871430-18902724 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Proline metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 204.2;liver: 438.6" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 448.7" "Cell type enhanced" "Detected in all" "astrocyte: 37.6;choroid plexus epithelial cell: 46.6" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 140.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004645, HPA006401, HPA072759" Enhanced Supported Mitochondria NA NA 82000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 70: DU4475 - Unknown function" "Cluster 93: Hepatocytes - Bile production & excretion" 18 Mitochondria "CAB004645: , HPA006401: , HPA072759: " "unprognostic (5.65e-3)" "unprognostic (6.15e-2)" "unprognostic (5.95e-3)" "unprognostic (3.01e-2)" "unprognostic (1.49e-2)" "unprognostic (1.37e-1)" "unprognostic (2.80e-1)" "unprognostic (8.91e-2)" "unprognostic (1.96e-1)" "unprognostic (1.03e-1)" "potential prognostic favorable (1.29e-5)" "unprognostic (5.17e-2)" "potential prognostic favorable (1.39e-4)" "unprognostic (3.18e-2)" "unprognostic (3.08e-3)" "unprognostic (2.05e-2)" "unprognostic (2.51e-1)" "unprognostic (1.92e-1)" "unprognostic (1.36e-1)" "unprognostic (5.06e-2)" "unprognostic (1.17e-1)" "unprognostic (1.60e-1)" "unprognostic (2.59e-2)" "unprognostic (1.95e-1)" "unprognostic (2.38e-1)" "unprognostic (6.06e-2)" "unprognostic (2.21e-1)" "unprognostic (1.33e-1)" "unprognostic (4.59e-1)" "unprognostic (2.54e-3)" "unprognostic (4.90e-2)" ALDH5A1 "SSADH, SSDH" ENSG00000112294 "Aldehyde dehydrogenase 5 family member A1" P51649 6 24494867-24537207 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 92.3" "Cell type enhanced" "Detected in many" "Fallopian tube ciliated cells: 62.9;Hepatocytes: 116.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "lymphoma: 51.3" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Spleen - B-cells (Spleen), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029715, HPA029716" Enhanced Supported Mitochondria NA NA 87000 "Cluster 24: Non-specific - Transcription" "Cluster 36: Brain & Liver - Signaling" "Cluster 1: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 109: Neurons - Neuronal signaling" 6 Mitochondria "HPA029715: , HPA029716: " "unprognostic (9.37e-3)" "unprognostic (3.47e-1)" "unprognostic (2.70e-1)" "unprognostic (6.38e-2)" "unprognostic (2.05e-1)" "unprognostic (1.39e-2)" "unprognostic (4.97e-1)" "unprognostic (1.83e-1)" "unprognostic (1.59e-1)" "unprognostic (1.76e-1)" "validated prognostic favorable (1.00e-6)" "validated prognostic favorable (9.16e-5)" "unprognostic (1.23e-1)" "potential prognostic favorable (5.56e-4)" "unprognostic (2.15e-3)" "unprognostic (5.06e-2)" "unprognostic (2.11e-2)" "unprognostic (4.56e-2)" "unprognostic (8.86e-3)" "unprognostic (1.68e-3)" "unprognostic (1.37e-1)" "unprognostic (1.23e-2)" "unprognostic (3.56e-2)" "unprognostic (2.08e-1)" "unprognostic (1.54e-2)" "unprognostic (2.56e-1)" "unprognostic (2.89e-2)" "unprognostic (1.59e-2)" "unprognostic (1.03e-1)" "unprognostic (1.35e-1)" "unprognostic (2.60e-1)" ALDH6A1 MMSDH ENSG00000119711 "Aldehyde dehydrogenase 6 family member A1" Q02252 14 74056847-74084492 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "kidney: 353.5;liver: 342.8" "Cell type enhanced" "Detected in many" "Hepatocytes: 630.8;Parietal cells: 213.9;Proximal tubule cells: 141.5;Retinal pigment epithelial cells: 162.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 43.2" "Lineage enriched" "Detected in all" 4 "granulocytes: 43.2" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Spleen - Fibroblasts_2, Stomach - Parietal cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029072, HPA029073, HPA029074, HPA029075" Enhanced Enhanced Mitochondria No No 44000 "Cluster 41: Basophils - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 93: Hepatocytes - Bile production & excretion" 1 Mitochondria "HPA029072: , HPA029073: , HPA029074: , HPA029075: " "unprognostic (6.72e-2)" "unprognostic (1.61e-1)" "unprognostic (4.28e-1)" "unprognostic (6.76e-2)" "unprognostic (3.53e-2)" "unprognostic (1.04e-1)" "unprognostic (3.76e-2)" "unprognostic (2.16e-1)" "unprognostic (3.37e-1)" "unprognostic (1.06e-1)" "validated prognostic favorable (6.38e-11)" "validated prognostic favorable (1.97e-4)" "potential prognostic favorable (2.45e-4)" "unprognostic (3.74e-3)" "unprognostic (9.27e-2)" "unprognostic (1.57e-3)" "unprognostic (1.66e-1)" "unprognostic (2.59e-1)" "unprognostic (3.11e-1)" "unprognostic (2.30e-1)" "unprognostic (3.38e-3)" "unprognostic (4.12e-1)" "unprognostic (5.36e-2)" "unprognostic (1.39e-1)" "unprognostic (1.90e-2)" "unprognostic (2.82e-3)" "unprognostic (5.65e-2)" "unprognostic (4.75e-2)" "unprognostic (1.65e-1)" "unprognostic (1.21e-3)" "unprognostic (1.83e-2)" ALDH7A1 "ATQ1, EPD, PDE" ENSG00000164904 "Aldehyde dehydrogenase 7 family member A1" P49419 5 126531200-126595362 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 151.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 792.4;Migrating cytotrophoblasts: 388.0;Ovarian stromal cells: 327.3;Syncytiotrophoblasts: 258.9" "Cell type enhanced" "Detected in all" "astrocyte: 240.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 6.3" "Lineage enriched" "Detected in many" 5 "dendritic cells: 6.3" "Cancer enhanced" "Detected in all" "Rhabdoid: 301.3" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023296, HPA053675" Enhanced Supported Mitochondria,Cytosol Yes No 750000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 36: Brain & Liver - Signaling" "Cluster 39: Astrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 9 Mitochondria Cytosol "HPA023296: , HPA053675: " "unprognostic (1.60e-2)" "unprognostic (7.77e-2)" "unprognostic (7.23e-2)" "unprognostic (4.49e-2)" "unprognostic (2.17e-2)" "unprognostic (8.81e-3)" "unprognostic (1.05e-1)" "unprognostic (8.18e-3)" "unprognostic (1.28e-1)" "unprognostic (2.46e-1)" "potential prognostic favorable (2.87e-12)" "unprognostic (1.68e-2)" "unprognostic (6.78e-2)" "unprognostic (1.53e-3)" "unprognostic (1.05e-3)" "unprognostic (1.19e-1)" "unprognostic (7.19e-2)" "potential prognostic unfavorable (1.31e-4)" "unprognostic (1.96e-2)" "unprognostic (3.61e-2)" "unprognostic (1.09e-1)" "potential prognostic unfavorable (6.45e-4)" "unprognostic (1.32e-1)" "unprognostic (4.04e-1)" "unprognostic (5.85e-3)" "unprognostic (8.06e-2)" "unprognostic (3.74e-1)" "unprognostic (2.28e-1)" "unprognostic (3.72e-2)" "unprognostic (1.63e-2)" "unprognostic (6.32e-2)" ALDH8A1 ALDH12 ENSG00000118514 "Aldehyde dehydrogenase 8 family member A1" Q9H2A2 6 134917393-134950115 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 24 "kidney: 67.2;liver: 231.1" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 21.0;Epicardial cells: 88.7;Hepatocytes: 171.6;Oligodendrocytes: 25.7;Proximal tubule cells: 81.5;Renal collecting duct principal cells: 46.7" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Kidney Renal Clear Cell Carcinoma (TCGA): 29.2;Kidney Renal Papillary Cell Carcinoma (TCGA): 46.0;Liver Hepatocellular Carcinoma (TCGA): 38.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.4" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in some" 8 "Rhabdoid: 15.0" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA026292, HPA055414" Enhanced Approved Nucleoplasm,Centrosome NA NA 56000 "Cluster 46: Basophils - Proteolysis" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 9: Non-specific - Receptor signaling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 88: Proximal tubular cells - Transmembrane transport" Centrosome Nucleoplasm "HPA026292: , HPA055414: " "unprognostic (1.44e-1)" "unprognostic (2.20e-1)" "unprognostic (2.79e-2)" "unprognostic (1.56e-1)" "unprognostic (1.03e-2)" "unprognostic (1.14e-2)" "unprognostic (2.89e-1)" "potential prognostic favorable (3.12e-5)" "unprognostic (6.12e-3)" "unprognostic (1.03e-2)" "unprognostic (3.79e-3)" "potential prognostic favorable (3.18e-5)" "unprognostic (1.88e-1)" "unprognostic (7.28e-2)" "unprognostic (7.29e-2)" "unprognostic (1.54e-1)" "unprognostic (9.09e-2)" "unprognostic (1.97e-3)" ALDH9A1 "ALDH4, ALDH7, ALDH9, E3" ENSG00000143149 "Aldehyde dehydrogenase 9 family member A1" P49189 1 165662216-165698562 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 298.0;Esophageal apical cells: 786.4;Esophageal suprabasal cells: 428.5;Müller glia: 273.5;Retinal pigment epithelial cells: 225.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "HPA006077, HPA010873" Approved Approved Cytosol "Intracellular and membrane" Enzyme NA NA 3200000 "Cluster 21: Neutrophils - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 45: Non-specific - Nuclear processes" "Cluster 85: Squamous epithelial cells - Keratinization" 4 Cytosol "HPA006077: , HPA010873: " "unprognostic (1.97e-1)" "unprognostic (2.46e-1)" "unprognostic (7.64e-2)" "unprognostic (2.17e-1)" "unprognostic (1.52e-1)" "unprognostic (1.43e-2)" "unprognostic (5.95e-2)" "unprognostic (2.79e-3)" "unprognostic (1.88e-1)" "potential prognostic unfavorable (5.31e-4)" "potential prognostic favorable (2.64e-7)" "unprognostic (1.18e-2)" "unprognostic (1.07e-1)" "unprognostic (4.88e-2)" "unprognostic (1.67e-3)" "unprognostic (1.10e-1)" "unprognostic (9.90e-2)" "unprognostic (2.32e-1)" "unprognostic (1.06e-1)" "unprognostic (8.35e-2)" "unprognostic (1.77e-1)" "validated prognostic favorable (8.54e-4)" "validated prognostic favorable (4.40e-4)" "unprognostic (6.85e-2)" "unprognostic (3.19e-1)" "unprognostic (2.40e-2)" "unprognostic (8.03e-2)" "unprognostic (3.08e-1)" "unprognostic (1.35e-2)" "unprognostic (1.20e-1)" "unprognostic (2.71e-1)" ALDOA ENSG00000149925 "Aldolase, fructose-bisphosphate A" P04075 16 30064164-30070457 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis Lyase "Cancer-related genes, Disease variant, Glycogen storage disease, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "skeletal muscle: 25093.7;tongue: 8554.2" "Cell type enhanced" "Detected in many" "Astrocytes: 79.9;Bergmann glia: 100.2;Brain excitatory neurons: 129.7;Brain inhibitory neurons: 120.9;Choroid plexus epithelial cells: 52.6;Ependymal cells: 83.8;Microglia: 42.5;Oligodendrocyte progenitor cells: 51.4;Oligodendrocytes: 83.6;Other brain neurons: 204.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004177, CAB006252" Supported Approved Cytosol NA NA 310000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 24: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 98: Neurons - Neurotransmission & signaling" 40 Cytosol "CAB006252: , HPA004177: " "unprognostic (3.48e-3)" "unprognostic (2.04e-2)" "unprognostic (3.71e-2)" "unprognostic (1.30e-2)" "unprognostic (9.58e-2)" "unprognostic (6.58e-2)" "unprognostic (4.23e-3)" "unprognostic (1.08e-1)" "unprognostic (5.89e-3)" "unprognostic (5.50e-2)" "potential prognostic favorable (4.52e-4)" "unprognostic (4.66e-2)" "unprognostic (3.20e-1)" "validated prognostic unfavorable (4.48e-6)" "validated prognostic unfavorable (7.80e-6)" "validated prognostic unfavorable (1.56e-6)" "validated prognostic unfavorable (7.09e-4)" "unprognostic (1.25e-1)" "unprognostic (2.53e-1)" "unprognostic (8.15e-2)" "unprognostic (1.38e-1)" "unprognostic (1.77e-3)" "unprognostic (4.30e-1)" "unprognostic (5.49e-2)" "unprognostic (1.39e-1)" "unprognostic (9.27e-2)" "unprognostic (1.98e-1)" "unprognostic (2.32e-1)" "unprognostic (7.76e-2)" "unprognostic (2.76e-2)" "unprognostic (1.02e-2)" ALDOB ENSG00000136872 "Aldolase, fructose-bisphosphate B" P05062 9 101420560-101449664 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis Lyase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 25 "intestine: 5987.0;kidney: 6695.1;liver: 10467.2" "Cell type enriched" "Detected in many" 5 "Enterocytes: 19887.7" "Cell type enhanced" "Detected in many" "hippocampal dentate gyrus: 5.6" "Cancer enriched" "Detected in many" 18 "Liver Hepatocellular Carcinoma (TCGA): 2587.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Gastric cancer: 10.2" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Pituitary gland - Corticotropes, Skin - Outer root sheath cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA002198, CAB020827, HPA073201" Enhanced NA NA 290000000 "Cluster 76: Non-specific - Metabolism" "Cluster 34: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 1: Enterocytes - Absorption and Digestion" 15 "CAB020827: , HPA002198: , HPA073201: " "unprognostic (1.23e-1)" "unprognostic (2.84e-3)" "unprognostic (3.73e-2)" "unprognostic (2.88e-1)" "validated prognostic favorable (1.97e-8)" "validated prognostic favorable (5.64e-7)" "unprognostic (1.26e-1)" "unprognostic (1.30e-3)" "potential prognostic favorable (3.11e-5)" "unprognostic (4.73e-2)" "unprognostic (5.41e-2)" "unprognostic (2.30e-2)" "unprognostic (4.94e-3)" "unprognostic (4.81e-2)" "unprognostic (3.85e-2)" "unprognostic (1.59e-1)" "unprognostic (1.51e-1)" ALDOC ENSG00000109107 "Aldolase, fructose-bisphosphate C" P09972 17 28573115-28576948 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis Lyase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "brain: 1156.4;retina: 1098.1" "Group enriched" "Detected in some" 4 "Astrocytes: 106.1;Bergmann glia: 87.7;Brain excitatory neurons: 33.9;Brain inhibitory neurons: 38.7;Oligodendrocyte progenitor cells: 46.2;Other brain neurons: 45.4" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 4 "Glioblastoma Multiforme (TCGA): 421.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipocytes (Visceral), Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003282, CAB020828, HPA067442" Enhanced Supported Approved "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol" Yes No 56000000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 24: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 98: Neurons - Neurotransmission & signaling" 8 "Nucleoplasm, Nucleoli fibrillar center" "Vesicles, Cytosol" "CAB020828: , HPA003282: , HPA067442: " "unprognostic (1.09e-1)" "unprognostic (1.00e-1)" "unprognostic (1.43e-1)" "unprognostic (4.88e-3)" "unprognostic (6.11e-2)" "unprognostic (2.05e-1)" "unprognostic (2.18e-1)" "potential prognostic favorable (2.98e-4)" "potential prognostic unfavorable (8.42e-4)" "unprognostic (2.13e-3)" "unprognostic (3.70e-3)" "unprognostic (2.26e-2)" "unprognostic (2.85e-3)" "unprognostic (1.01e-1)" "unprognostic (5.82e-2)" "unprognostic (4.02e-2)" "unprognostic (7.39e-2)" "unprognostic (1.56e-2)" "unprognostic (5.37e-2)" "unprognostic (1.92e-3)" "unprognostic (1.09e-1)" "unprognostic (3.32e-1)" "unprognostic (3.88e-1)" "unprognostic (7.09e-3)" "unprognostic (5.11e-1)" "unprognostic (2.64e-1)" "unprognostic (1.33e-1)" "unprognostic (5.57e-2)" "unprognostic (2.73e-1)" "unprognostic (4.58e-2)" "unprognostic (1.23e-2)" ALG1 "CDG1K, HMAT1, HMT-1, Mat-1" ENSG00000033011 "ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase" Q9BT22 16 5033702-5087379 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 93.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060392 Approved Approved "Nucleoli fibrillar center,Endoplasmic reticulum" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 17: Choroid plexus - Cilium" "Cluster 54: Non-specific - Transcription" "Cluster 79: Photoreceptor cells - Phototransduction" 2 "Endoplasmic reticulum" "Nucleoli fibrillar center" "HPA060392: " "unprognostic (1.75e-1)" "unprognostic (3.87e-3)" "unprognostic (7.81e-3)" "unprognostic (2.64e-1)" "unprognostic (1.41e-2)" "unprognostic (3.94e-2)" "unprognostic (1.67e-2)" "unprognostic (2.87e-3)" "unprognostic (2.71e-2)" "unprognostic (1.64e-1)" "unprognostic (9.38e-3)" "unprognostic (1.05e-2)" "unprognostic (3.32e-2)" "unprognostic (1.04e-2)" "potential prognostic unfavorable (6.92e-4)" "unprognostic (1.38e-2)" "unprognostic (1.10e-1)" "unprognostic (6.03e-2)" "unprognostic (2.78e-1)" "unprognostic (2.56e-1)" "unprognostic (9.39e-2)" "unprognostic (3.37e-2)" "unprognostic (1.07e-1)" "unprognostic (5.31e-1)" "unprognostic (5.96e-2)" "unprognostic (2.20e-1)" "unprognostic (6.67e-2)" "unprognostic (1.09e-1)" "unprognostic (5.63e-2)" "unprognostic (2.09e-2)" "unprognostic (5.45e-3)" ALG10 "ALG10A, DIE2, FLJ14751" ENSG00000139133 "ALG10 alpha-1,2-glucosyltransferase" Q5BKT4 12 34022468-34029694 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 14.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "HPA043329, HPA063387" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 9 "Endoplasmic reticulum" "HPA043329: , HPA063387: " "unprognostic (1.14e-1)" "unprognostic (6.06e-3)" "unprognostic (1.09e-1)" "unprognostic (2.37e-1)" "unprognostic (1.31e-2)" "unprognostic (3.15e-1)" "unprognostic (5.50e-1)" "unprognostic (4.93e-1)" "unprognostic (1.94e-1)" "unprognostic (3.71e-2)" "potential prognostic favorable (1.70e-6)" "unprognostic (1.05e-1)" "unprognostic (3.99e-1)" "potential prognostic unfavorable (6.05e-4)" "unprognostic (6.46e-2)" "unprognostic (1.41e-3)" "potential prognostic unfavorable (2.18e-4)" "unprognostic (7.03e-2)" "unprognostic (2.27e-2)" "unprognostic (1.36e-2)" "unprognostic (6.51e-2)" "unprognostic (1.34e-1)" "potential prognostic unfavorable (5.93e-4)" "unprognostic (6.97e-2)" "potential prognostic favorable (1.88e-5)" "unprognostic (9.16e-2)" "unprognostic (7.39e-2)" "unprognostic (4.49e-2)" "unprognostic (1.22e-1)" "unprognostic (2.85e-1)" "unprognostic (2.16e-1)" ALG10B KCR1 ENSG00000175548 "ALG10 alpha-1,2-glucosyltransferase B" Q5I7T1 12 38316762-38329721 "Enzymes, Essential proteins, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "HPA043329, HPA063387" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 42: Retina - Visual perception" "Cluster 55: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 2 "Endoplasmic reticulum" "HPA043329: , HPA063387: " "unprognostic (4.98e-2)" "unprognostic (2.00e-1)" "unprognostic (1.98e-1)" "unprognostic (1.07e-2)" "unprognostic (2.13e-2)" "unprognostic (5.45e-2)" "unprognostic (3.85e-1)" "unprognostic (2.54e-1)" "unprognostic (1.93e-1)" "unprognostic (1.48e-2)" "potential prognostic favorable (6.77e-4)" "unprognostic (9.00e-2)" "unprognostic (2.06e-1)" "unprognostic (1.62e-3)" "unprognostic (3.50e-2)" "unprognostic (8.18e-2)" "unprognostic (1.21e-3)" "unprognostic (4.17e-2)" "unprognostic (9.89e-2)" "unprognostic (1.26e-1)" "unprognostic (8.89e-2)" "unprognostic (1.39e-2)" "unprognostic (1.41e-2)" "unprognostic (6.21e-2)" "unprognostic (1.42e-3)" "unprognostic (1.45e-2)" "unprognostic (6.48e-2)" "unprognostic (6.75e-2)" "unprognostic (1.40e-1)" "unprognostic (6.42e-2)" "unprognostic (8.95e-2)" ALG11 "CDG1P, KIAA0266" ENSG00000253710 "ALG11 alpha-1,2-mannosyltransferase" Q2TAA5 13 52012391-52079232 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047214 Approved NA NA "Cluster 41: Basophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 9: Non-specific - Receptor signaling" "Cluster 19: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 22 "HPA047214: " "unprognostic (2.39e-1)" "unprognostic (2.21e-2)" "unprognostic (2.24e-1)" "unprognostic (1.48e-2)" "unprognostic (1.28e-1)" "unprognostic (1.84e-1)" "unprognostic (2.36e-2)" "unprognostic (7.66e-2)" "unprognostic (3.34e-1)" "unprognostic (5.39e-2)" "validated prognostic favorable (3.46e-8)" "validated prognostic favorable (8.03e-4)" "unprognostic (2.73e-1)" "unprognostic (3.48e-2)" "unprognostic (1.29e-1)" "unprognostic (2.32e-1)" "unprognostic (2.65e-2)" "unprognostic (2.72e-1)" "unprognostic (1.79e-1)" "unprognostic (1.31e-2)" "potential prognostic unfavorable (1.36e-4)" "unprognostic (8.21e-2)" "unprognostic (8.50e-2)" "unprognostic (1.13e-1)" "unprognostic (4.15e-1)" "unprognostic (4.30e-2)" "unprognostic (5.21e-2)" "unprognostic (1.85e-1)" "unprognostic (3.06e-1)" "unprognostic (6.90e-2)" "unprognostic (6.47e-2)" ALG12 "CDG1G, ECM39" ENSG00000182858 "ALG12 alpha-1,6-mannosyltransferase" Q9BV10 22 49900229-49918438 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003076, HPA051665" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 70: Non-specific - Protein processing" "Cluster 6: Non-specific - Immune response" "Cluster 66: Non-specific - Mitochondria" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" "Endoplasmic reticulum" "HPA003076: , HPA051665: " "unprognostic (5.03e-2)" "unprognostic (1.02e-1)" "unprognostic (4.69e-3)" "unprognostic (1.34e-1)" "unprognostic (1.24e-2)" "unprognostic (1.55e-2)" "unprognostic (2.02e-1)" "unprognostic (3.40e-1)" "unprognostic (1.12e-1)" "unprognostic (3.27e-1)" "unprognostic (8.13e-3)" "unprognostic (1.95e-1)" "potential prognostic favorable (1.25e-5)" "unprognostic (6.00e-3)" "unprognostic (6.46e-2)" "unprognostic (2.17e-1)" "unprognostic (2.52e-1)" "unprognostic (3.32e-3)" "unprognostic (3.10e-2)" "unprognostic (1.60e-2)" "unprognostic (9.35e-2)" "unprognostic (1.19e-1)" "unprognostic (3.49e-2)" "unprognostic (1.67e-1)" "unprognostic (1.52e-1)" "unprognostic (1.76e-1)" "unprognostic (8.66e-2)" "unprognostic (7.30e-2)" "unprognostic (3.16e-1)" "unprognostic (1.43e-1)" "unprognostic (5.16e-2)" ALG13 "CDG1S, CXorf45, FLJ23018, GLT28D1, MDS031, TDRD13, YGL047W" ENSG00000101901 "ALG13 UDP-N-acetylglucosaminyltransferase subunit" Q9NP73 X 111665811-111760649 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Glycosyltransferase, Hydrolase, Multifunctional enzyme, Protease, Thiol protease, Transferase" "Congenital disorder of glycosylation, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Sertoli cells: 342.5;Somatotrophs: 356.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002853, HPA005498" Approved Approved Vesicles,Cytosol NA NA 26000000 "Cluster 25: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 36: Non-specific - mRNA processing" "Cluster 103: Non-specific - Basic cellular processes" 7 Vesicles Cytosol "HPA002853: , HPA005498: " "unprognostic (5.80e-2)" "unprognostic (9.52e-3)" "unprognostic (1.73e-1)" "unprognostic (1.36e-1)" "unprognostic (6.88e-2)" "unprognostic (6.13e-2)" "unprognostic (2.07e-1)" "unprognostic (1.62e-1)" "potential prognostic unfavorable (4.93e-4)" "unprognostic (1.49e-3)" "potential prognostic favorable (1.39e-4)" "unprognostic (2.14e-2)" "unprognostic (1.48e-1)" "unprognostic (1.69e-1)" "unprognostic (3.42e-2)" "unprognostic (1.09e-1)" "unprognostic (2.99e-2)" "unprognostic (1.83e-2)" "unprognostic (2.56e-1)" "unprognostic (4.75e-3)" "unprognostic (8.20e-2)" "unprognostic (2.30e-1)" "unprognostic (2.70e-2)" "unprognostic (5.39e-2)" "unprognostic (9.56e-3)" "unprognostic (1.98e-1)" "potential prognostic unfavorable (9.32e-4)" "unprognostic (5.62e-2)" "unprognostic (1.09e-1)" "unprognostic (2.43e-1)" "unprognostic (1.93e-1)" ALG14 MGC19780 ENSG00000172339 "ALG14 UDP-N-acetylglucosaminyltransferase subunit" Q96F25 1 94974405-95072951 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Congenital myasthenic syndrome, Disease variant, Epilepsy, Intellectual disability, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031829 Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 22: Epididymis - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 44: Plasma cells - Antibody production & secretion" Nucleoli Nucleoplasm "HPA031829: " "unprognostic (3.95e-1)" "unprognostic (1.43e-1)" "unprognostic (1.01e-1)" "unprognostic (1.21e-1)" "unprognostic (3.42e-2)" "unprognostic (4.38e-3)" "unprognostic (4.87e-3)" "unprognostic (5.36e-2)" "unprognostic (2.27e-2)" "potential prognostic unfavorable (9.58e-4)" "unprognostic (1.14e-3)" "unprognostic (1.92e-3)" "unprognostic (7.67e-2)" "unprognostic (1.23e-1)" "unprognostic (2.59e-2)" "unprognostic (2.09e-1)" "unprognostic (3.24e-1)" "unprognostic (8.28e-2)" "unprognostic (3.62e-2)" "unprognostic (1.56e-1)" "unprognostic (6.89e-2)" "unprognostic (2.86e-2)" "unprognostic (1.87e-1)" "unprognostic (3.28e-1)" "unprognostic (6.00e-2)" "unprognostic (1.55e-2)" "unprognostic (1.14e-1)" "unprognostic (7.26e-2)" "unprognostic (5.39e-2)" "unprognostic (7.57e-2)" "unprognostic (1.96e-1)" ALG1L2 ENSG00000251287 "ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase like 2" C9J202 3 130081831-130113227 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "retina: 2.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 19.1;Epicardial cells: 38.7;Hematopoietic stem cells: 15.0;Paneth cells: 15.5;pDCs: 13.4;Tuft cells: 23.1" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Ovary Serous Cystadenocarcinoma (TCGA): 1.1;Testicular Germ Cell Tumor (TCGA): 1.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "plasmacytoid DC: 1.0" "Lineage enriched" "Detected in single" 4 "dendritic cells: 1.0" "Not detected" "Not detected" HPA060392 Uncertain Uncertain "Nucleoli fibrillar center,Endoplasmic reticulum" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 42: Retina - Visual perception" "Cluster 6: Non-specific - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "Endoplasmic reticulum" "Nucleoli fibrillar center" "HPA060392: " "unprognostic (1.82e-1)" "unprognostic (5.60e-3)" "unprognostic (1.01e-1)" "unprognostic (3.34e-1)" ALG2 "CDG1I, CDGIi, FLJ14511, hALPG2, NET38" ENSG00000119523 "ALG2 alpha-1,3/1,6-mannosyltransferase" Q9H553 9 99216425-99221942 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 111.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041512, HPA041601" Approved Approved "Golgi apparatus" NA No "Cluster 13: Non-specific - Mitochondria" "Cluster 22: Epididymis - Mixed function" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Secretory pathway" 13 "Golgi apparatus" "HPA041512: , HPA041601: " "unprognostic (2.08e-2)" "unprognostic (1.46e-2)" "unprognostic (4.84e-2)" "unprognostic (2.32e-1)" "unprognostic (2.34e-1)" "unprognostic (2.58e-2)" "unprognostic (1.54e-3)" "unprognostic (7.93e-2)" "potential prognostic unfavorable (2.71e-4)" "unprognostic (1.02e-1)" "potential prognostic favorable (2.29e-8)" "unprognostic (2.63e-3)" "unprognostic (1.37e-2)" "unprognostic (1.08e-3)" "unprognostic (8.64e-2)" "unprognostic (2.24e-1)" "unprognostic (3.52e-1)" "unprognostic (5.19e-2)" "unprognostic (9.92e-2)" "unprognostic (2.20e-1)" "unprognostic (6.18e-2)" "unprognostic (1.13e-1)" "unprognostic (2.31e-1)" "unprognostic (1.80e-1)" "unprognostic (1.08e-2)" "unprognostic (2.44e-3)" "unprognostic (2.98e-1)" "unprognostic (3.72e-2)" "unprognostic (2.21e-1)" "unprognostic (1.34e-1)" "unprognostic (1.26e-2)" ALG3 "CDGS4, D16Ertd36e, Not56, NOT56L" ENSG00000214160 "ALG3 alpha-1,3- mannosyltransferase" Q92685 3 184242301-184249548 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 115.3;Extravillous trophoblasts: 133.8;Late spermatids: 374.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Macrophages, Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045103 Enhanced NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 70: Non-specific - Protein processing" "Cluster 44: Non-specific - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 16 "HPA045103: " "unprognostic (2.71e-3)" "potential prognostic unfavorable (2.34e-4)" "unprognostic (4.67e-2)" "unprognostic (1.36e-1)" "unprognostic (9.77e-2)" "unprognostic (1.60e-1)" "unprognostic (1.68e-1)" "unprognostic (3.50e-2)" "unprognostic (1.59e-3)" "unprognostic (2.62e-2)" "validated prognostic unfavorable (4.60e-6)" "validated prognostic unfavorable (1.32e-5)" "potential prognostic unfavorable (3.92e-4)" "validated prognostic unfavorable (1.50e-6)" "validated prognostic unfavorable (1.02e-4)" "validated prognostic unfavorable (4.02e-5)" "validated prognostic unfavorable (1.03e-4)" "unprognostic (3.18e-2)" "unprognostic (1.50e-3)" "unprognostic (1.08e-1)" "unprognostic (1.17e-1)" "unprognostic (3.32e-3)" "unprognostic (3.04e-1)" "unprognostic (4.15e-2)" "unprognostic (1.52e-1)" "unprognostic (3.40e-1)" "unprognostic (2.01e-2)" "unprognostic (1.09e-1)" "unprognostic (2.14e-1)" "unprognostic (7.58e-2)" "unprognostic (7.69e-2)" ALG5 bA421P11.2 ENSG00000120697 "ALG5 dolichyl-phosphate beta-glucosyltransferase" Q9Y673 13 36949738-37000763 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 237.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007989 Approved Approved Cytosol No No "Cluster 13: Non-specific - Mitochondria" "Cluster 70: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 19: Non-specific - Unknown function" "Cluster 8: Non-specific - Secretory pathway" Cytosol "HPA007989: " "unprognostic (2.07e-2)" "unprognostic (2.03e-1)" "potential prognostic unfavorable (2.78e-4)" "unprognostic (6.22e-2)" "unprognostic (2.62e-2)" "unprognostic (2.47e-1)" "unprognostic (9.45e-2)" "unprognostic (3.30e-3)" "potential prognostic unfavorable (3.49e-5)" "unprognostic (2.82e-1)" "potential prognostic favorable (2.56e-10)" "unprognostic (6.98e-3)" "unprognostic (1.13e-2)" "unprognostic (1.96e-2)" "unprognostic (2.74e-2)" "unprognostic (1.60e-2)" "unprognostic (4.26e-1)" "unprognostic (1.61e-1)" "unprognostic (1.27e-1)" "unprognostic (5.94e-2)" "unprognostic (1.76e-2)" "unprognostic (8.17e-2)" "unprognostic (2.35e-2)" "unprognostic (2.20e-1)" "unprognostic (4.81e-2)" "unprognostic (4.68e-2)" "unprognostic (2.09e-2)" "unprognostic (1.80e-1)" "unprognostic (1.67e-1)" "unprognostic (1.63e-2)" "unprognostic (1.82e-2)" ALG6 ENSG00000088035 "ALG6 alpha-1,3-glucosyltransferase" Q9Y672 1 63367575-63438553 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062536, HPA076130" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 2 "Endoplasmic reticulum" "HPA062536: , HPA076130: " "unprognostic (1.01e-1)" "unprognostic (5.71e-2)" "unprognostic (3.23e-2)" "unprognostic (4.64e-3)" "unprognostic (3.58e-2)" "unprognostic (3.28e-1)" "potential prognostic favorable (7.39e-4)" "unprognostic (3.80e-1)" "unprognostic (2.67e-1)" "unprognostic (9.63e-2)" "unprognostic (2.75e-2)" "unprognostic (5.90e-2)" "unprognostic (3.41e-1)" "unprognostic (1.94e-3)" "unprognostic (2.26e-2)" "unprognostic (1.88e-1)" "unprognostic (1.15e-2)" "unprognostic (3.00e-1)" "unprognostic (6.25e-2)" "unprognostic (1.98e-2)" "unprognostic (2.26e-1)" "unprognostic (2.87e-2)" "unprognostic (4.23e-2)" "unprognostic (1.41e-1)" "unprognostic (1.03e-1)" ALG8 MGC2840 ENSG00000159063 "ALG8 alpha-1,3-glucosyltransferase" Q9BVK2 11 78095244-78139660 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 124.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051898 Approved Approved Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 22: Epididymis - Mixed function" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 24: Non-specific - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 10 Nucleoplasm "HPA051898: " "unprognostic (5.16e-2)" "unprognostic (8.87e-2)" "unprognostic (5.52e-1)" "unprognostic (2.87e-2)" "unprognostic (4.36e-2)" "unprognostic (2.70e-2)" "unprognostic (8.86e-2)" "unprognostic (4.21e-2)" "unprognostic (1.13e-2)" "unprognostic (6.83e-3)" "potential prognostic favorable (6.46e-4)" "unprognostic (5.34e-2)" "unprognostic (1.29e-2)" "unprognostic (3.25e-3)" "unprognostic (2.85e-3)" "potential prognostic unfavorable (7.25e-5)" "unprognostic (7.78e-3)" "unprognostic (3.62e-2)" "unprognostic (1.47e-1)" "potential prognostic favorable (8.31e-4)" "unprognostic (2.36e-1)" "unprognostic (5.00e-3)" "unprognostic (1.36e-1)" "unprognostic (9.68e-2)" "unprognostic (7.11e-3)" "unprognostic (1.63e-1)" "unprognostic (8.95e-2)" "unprognostic (1.48e-1)" "unprognostic (9.23e-2)" "unprognostic (7.08e-2)" "unprognostic (6.93e-2)" ALG9 DIBD1 ENSG00000086848 "ALG9 alpha-1,2-mannosyltransferase" Q9H6U8 11 111782195-111871581 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 22.1;Bergmann glia: 26.3;Brain excitatory neurons: 29.5;Brain inhibitory neurons: 36.1;Choroid plexus epithelial cells: 30.2;Ependymal cells: 20.3;Microglia: 24.3;Oligodendrocyte progenitor cells: 26.7;Oligodendrocytes: 30.7;Other brain neurons: 33.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038575 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 8: Pancreas - Proteolysis" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 24: Non-specific - Unknown function" "Cluster 22: Non-specific - Basic cellular functions" 4 "Endoplasmic reticulum" "HPA038575: " "unprognostic (1.30e-1)" "unprognostic (2.37e-3)" "unprognostic (5.25e-2)" "unprognostic (5.05e-2)" "potential prognostic favorable (2.86e-5)" "unprognostic (3.12e-2)" "unprognostic (4.54e-2)" "unprognostic (2.28e-2)" "unprognostic (1.95e-3)" "unprognostic (1.05e-2)" "potential prognostic favorable (2.86e-6)" "unprognostic (5.30e-2)" "unprognostic (1.47e-1)" "unprognostic (2.51e-2)" "unprognostic (8.18e-2)" "unprognostic (2.13e-1)" "unprognostic (1.07e-1)" "unprognostic (8.84e-2)" "unprognostic (3.20e-1)" "unprognostic (6.55e-3)" "unprognostic (2.32e-1)" "unprognostic (1.37e-3)" "unprognostic (4.83e-3)" "unprognostic (1.43e-1)" "unprognostic (1.73e-2)" "unprognostic (6.25e-2)" "unprognostic (2.49e-2)" "unprognostic (2.65e-2)" "unprognostic (4.62e-1)" "unprognostic (1.68e-1)" "unprognostic (2.44e-1)" ALK "ALK1, CD246" ENSG00000171094 "ALK receptor tyrosine kinase" Q9UM73 2 29192774-29921586 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.9;pituitary gland: 2.4;testis: 1.5" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 138.3;Brain inhibitory neurons: 202.5;Early spermatids: 228.9;Lactotrophs: 1017.9;Late spermatids: 260.6;Oligodendrocyte progenitor cells: 306.6;Retinal amacrine cells: 128.4;Salivary ionocytes: 417.3;Schwann cells: 321.2" "Cell type enhanced" "Detected in all" "LAMP5-LHX6 and Chandelier: 876.2" "Group enriched" "Detected in some" 4 "Glioblastoma Multiforme (TCGA): 2.1;Ovary Serous Cystadenocarcinoma (TCGA): 1.2;Skin Cutaneous Melanoma (TCGA): 2.9;Thyroid Carcinoma (TCGA): 1.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 9 "Neuroblastoma: 84.2" "Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Pituitary gland - Lactotropes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010694 Approved Supported "Plasma membrane" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 109 "Plasma membrane" "HPA010694: " "unprognostic (8.98e-2)" "unprognostic (9.10e-2)" "unprognostic (1.61e-1)" "unprognostic (2.25e-1)" "unprognostic (2.65e-3)" "unprognostic (2.35e-1)" ALKAL1 "AUGB, FAM150A, UNQ9433" ENSG00000196711 "ALK and LTK ligand 1" Q6UXT8 8 52534037-52565430 "Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "gallbladder: 2.2;thyroid gland: 2.2;urinary bladder: 1.5" "Cell type enhanced" "Detected in some" "Breast lactating cells: 12.6;Cholangiocytes: 15.7;Conjunctival goblet cells: 5.8;Endometrial secretory cells: 6.5;Paneth cells: 7.7;Salivary basal cells: 5.0;Salivary ionocytes: 30.0;Urothelial cells: 13.3" "Cell type enhanced" "Detected in some" "CGE interneuron: 3.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lung cancer: 2.0" "Liver - Cholangiocytes, Minor Salivary Gland - Minor salivary glandular cells, Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA027368 Uncertain "Secreted to blood" Cytokine NA NA "Cluster 38: Non-specific - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 69: Urothelial cells - Basic cellular functions" 2 "HPA027368: " "unprognostic (4.69e-2)" "unprognostic (2.97e-1)" "unprognostic (1.55e-1)" "unprognostic (1.53e-1)" "unprognostic (2.34e-1)" "unprognostic (1.23e-2)" "unprognostic (1.35e-1)" "unprognostic (1.55e-1)" "unprognostic (5.46e-2)" "unprognostic (2.73e-1)" "unprognostic (5.98e-2)" "unprognostic (1.48e-2)" "unprognostic (2.88e-1)" ALKAL2 "AUGA, FAM150B" ENSG00000189292 "ALK and LTK ligand 2" Q6UX46 2 279558-288851 "Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 212.1" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 150.2;Cholangiocytes: 142.5;Early spermatids: 87.7;Endometrial glandular cells: 51.2;Endometrial luminal cells: 68.5;Granulosa cells: 75.4;Late primary spermatocytes: 109.9;Late spermatids: 100.3;Ovarian stromal cells: 51.5;Pancreatic duct cells: 212.1;Undifferentiated spermatogonia: 58.6;Vascular smooth muscle cells: 68.8" "Cell type enhanced" "Detected in many" "amygdala excitatory: 14.8;vascular associated smooth muscle cell: 28.7" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 34.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 5.7;lymphoma: 14.9" "Kidney - Proximal tubular cells, Liver - Cholangiocytes, Skeletal muscle - Smooth muscle cells, Spleen - Fibroblasts_2" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 4 "amygdala: 3.3;basal ganglia: 2.1;cerebral cortex: 1.7;hippocampal formation: 2.3;spinal cord: 1.0" "Secreted to blood" Cytokine NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 6: Leukemia - Signal transduction" "Cluster 103: Non-specific - Basic cellular processes" 1 "potential prognostic favorable (5.06e-4)" "unprognostic (8.96e-3)" "unprognostic (1.81e-1)" "unprognostic (2.97e-2)" "unprognostic (3.50e-2)" "unprognostic (7.85e-2)" "unprognostic (7.84e-3)" "potential prognostic favorable (7.94e-5)" "unprognostic (3.11e-2)" "unprognostic (4.01e-3)" "unprognostic (1.27e-2)" "unprognostic (3.51e-2)" "unprognostic (2.76e-1)" "unprognostic (3.66e-1)" "unprognostic (6.67e-2)" "unprognostic (5.28e-2)" "unprognostic (2.51e-1)" "unprognostic (1.63e-1)" "unprognostic (4.93e-3)" "unprognostic (7.63e-2)" "unprognostic (1.21e-1)" "unprognostic (2.08e-2)" "unprognostic (8.37e-2)" "unprognostic (4.34e-2)" "unprognostic (5.67e-2)" ALKBH1 "ABH, alkB, ALKBH, hABH" ENSG00000100601 "AlkB homolog 1, histone H2A dioxygenase" Q13686 14 77672404-77708023 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, RNA repair, Transcription, Transcription regulation, Translation regulation" "Dioxygenase, Lyase, Multifunctional enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044087, HPA060061" Approved Supported "Nucleoplasm,Endoplasmic reticulum" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 7: Non-specific - Transcription" Nucleoplasm "Endoplasmic reticulum" "HPA044087: , HPA060061: " "unprognostic (1.74e-3)" "unprognostic (1.64e-1)" "unprognostic (3.82e-3)" "unprognostic (4.37e-2)" "unprognostic (2.59e-1)" "unprognostic (8.60e-3)" "unprognostic (1.57e-3)" "unprognostic (8.48e-3)" "unprognostic (2.23e-2)" "unprognostic (9.85e-3)" "validated prognostic favorable (1.53e-6)" "validated prognostic favorable (5.88e-6)" "unprognostic (2.21e-1)" "potential prognostic unfavorable (1.33e-5)" "unprognostic (1.49e-1)" "unprognostic (6.97e-3)" "unprognostic (2.06e-1)" "unprognostic (1.67e-2)" "unprognostic (3.57e-3)" "unprognostic (7.60e-2)" "unprognostic (2.60e-2)" "unprognostic (1.36e-1)" "unprognostic (2.74e-2)" "unprognostic (3.06e-1)" "unprognostic (6.95e-3)" "unprognostic (5.42e-3)" "unprognostic (1.98e-1)" "unprognostic (6.63e-2)" "unprognostic (4.32e-1)" "unprognostic (6.67e-2)" "unprognostic (5.64e-2)" ALKBH2 "ABH2, MGC90512" ENSG00000189046 "AlkB homolog 2, alpha-ketoglutarate dependent dioxygenase" Q6NS38 12 109088188-109093631 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 61.2;Oocytes: 110.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011198, HPA045392, HPA051976" Approved Supported "Nucleoplasm,Primary cilium,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 103: Non-specific - Basic cellular processes" 4 Nucleoplasm "Primary cilium, Cytosol" "CAB011198: , HPA045392: , HPA051976: " "unprognostic (1.16e-1)" "potential prognostic favorable (9.63e-5)" "unprognostic (2.13e-1)" "unprognostic (1.81e-1)" "unprognostic (5.85e-2)" "unprognostic (1.53e-2)" "unprognostic (1.82e-2)" "unprognostic (3.69e-3)" "unprognostic (7.56e-2)" "unprognostic (2.50e-1)" "unprognostic (4.14e-2)" "unprognostic (1.39e-1)" "unprognostic (9.34e-3)" "unprognostic (1.09e-1)" "unprognostic (3.15e-3)" "unprognostic (5.10e-2)" "unprognostic (2.51e-3)" "unprognostic (7.40e-3)" "unprognostic (3.93e-2)" "unprognostic (3.90e-1)" "unprognostic (2.22e-1)" "unprognostic (1.48e-2)" "unprognostic (1.46e-1)" "unprognostic (1.12e-2)" "unprognostic (4.98e-2)" "unprognostic (3.19e-2)" "unprognostic (3.63e-2)" "unprognostic (8.47e-3)" "unprognostic (4.59e-2)" "unprognostic (1.54e-2)" "unprognostic (1.57e-2)" ALKBH3 DEPC-1 ENSG00000166199 "AlkB homolog 3, alpha-ketoglutarate dependent dioxygenase" Q96Q83 11 43880811-43920274 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 131.3;Late spermatids: 130.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009674, HPA046489" Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 24: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 15 Nucleoplasm Mitochondria "HPA009674: , HPA046489: " "unprognostic (1.54e-1)" "unprognostic (2.18e-1)" "unprognostic (5.82e-2)" "unprognostic (1.96e-2)" "unprognostic (1.27e-3)" "unprognostic (2.13e-3)" "unprognostic (1.69e-3)" "unprognostic (1.84e-2)" "unprognostic (8.65e-3)" "unprognostic (1.91e-3)" "unprognostic (7.11e-2)" "unprognostic (1.62e-1)" "unprognostic (1.07e-1)" "unprognostic (2.29e-2)" "unprognostic (4.44e-2)" "unprognostic (1.80e-1)" "unprognostic (1.90e-3)" "unprognostic (2.15e-2)" "unprognostic (2.69e-1)" "unprognostic (5.64e-2)" "unprognostic (2.33e-1)" "unprognostic (3.22e-2)" "unprognostic (5.77e-2)" "unprognostic (1.09e-1)" "unprognostic (1.80e-2)" "unprognostic (1.89e-1)" "unprognostic (1.53e-1)" "unprognostic (2.56e-1)" "unprognostic (2.15e-1)" "unprognostic (3.49e-2)" "unprognostic (3.41e-1)" ALKBH4 FLJ20013 ENSG00000160993 "AlkB homolog 4, lysine demethylase" Q9NXW9 7 102456238-102464863 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Actin-binding, Chromatin regulator, Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051422 Approved NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 64: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 24: Neutrophils - Innate immunity signal integration" 12 "HPA051422: " "unprognostic (4.72e-2)" "unprognostic (1.03e-1)" "unprognostic (1.60e-2)" "unprognostic (8.92e-3)" "unprognostic (5.67e-2)" "unprognostic (2.98e-2)" "unprognostic (7.79e-3)" "unprognostic (2.31e-1)" "unprognostic (4.21e-2)" "unprognostic (1.87e-3)" "potential prognostic favorable (1.96e-4)" "unprognostic (4.26e-3)" "potential prognostic favorable (4.25e-5)" "unprognostic (1.13e-3)" "unprognostic (3.72e-2)" "unprognostic (4.45e-1)" "unprognostic (2.35e-2)" "unprognostic (1.97e-2)" "unprognostic (1.46e-2)" "unprognostic (5.02e-2)" "unprognostic (1.17e-1)" "potential prognostic favorable (7.97e-4)" "unprognostic (2.33e-1)" "unprognostic (1.32e-1)" "unprognostic (3.43e-1)" "unprognostic (4.73e-3)" "unprognostic (2.23e-2)" "unprognostic (1.36e-1)" "unprognostic (1.76e-1)" "unprognostic (1.25e-1)" "unprognostic (1.39e-1)" ALKBH5 "FLJ20308, OFOXD1" ENSG00000091542 "AlkB homolog 5, RNA demethylase" Q6P6C2 17 18183078-18209954 "Enzymes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 221.6" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Smooth muscle cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007196 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 27: Non-specific - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 20: Non-specific - Transcription regulation" 11 "Nucleoplasm, Cytosol" "Golgi apparatus" "HPA007196: " "unprognostic (2.69e-2)" "unprognostic (9.99e-2)" "unprognostic (2.02e-1)" "unprognostic (8.17e-3)" "unprognostic (2.61e-1)" "unprognostic (3.98e-2)" "unprognostic (1.59e-1)" "unprognostic (1.84e-1)" "unprognostic (2.00e-1)" "unprognostic (6.15e-2)" "potential prognostic favorable (2.22e-7)" "unprognostic (7.17e-3)" "unprognostic (2.50e-1)" "unprognostic (2.83e-1)" "unprognostic (1.94e-3)" "unprognostic (1.38e-1)" "unprognostic (1.10e-1)" "unprognostic (5.18e-2)" "unprognostic (4.99e-2)" "unprognostic (2.80e-1)" "unprognostic (2.24e-2)" "unprognostic (2.60e-2)" "unprognostic (2.53e-1)" "unprognostic (1.09e-1)" "unprognostic (8.76e-2)" "unprognostic (1.25e-1)" "unprognostic (1.86e-1)" "unprognostic (4.67e-2)" "unprognostic (2.92e-1)" "unprognostic (2.04e-3)" "unprognostic (8.81e-2)" ALKBH6 MGC15677 ENSG00000239382 "AlkB homolog 6" Q3KRA9 19 36009120-36014239 "Cancer-related genes, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 9.2;Bergmann glia: 6.7;Brain excitatory neurons: 12.0;Brain inhibitory neurons: 11.8;Choroid plexus epithelial cells: 3.8;Distal convoluted tubule cells: 4.4;Ependymal cells: 6.0;Loop of henle epithelial cells: 3.7;Microglia: 5.8;Oligodendrocyte progenitor cells: 4.9;Oligodendrocytes: 7.6;Other brain neurons: 15.2;Papillary tip epithelial cells: 4.6;Proximal tubule cells: 3.8;Renal collecting duct intercalated cells: 4.4;Renal collecting duct principal cells: 4.2;Renal connecting tubule cells: 4.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074340 Approved "Nucleoplasm,Focal adhesion sites" NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 98: Neurons - Neurotransmission & signaling" Nucleoplasm "Focal adhesion sites" "HPA074340: " "unprognostic (4.80e-2)" "unprognostic (1.67e-1)" "unprognostic (2.89e-1)" "unprognostic (7.09e-2)" "unprognostic (1.72e-1)" "unprognostic (4.55e-2)" "unprognostic (5.38e-2)" "unprognostic (1.57e-1)" "unprognostic (3.17e-1)" "unprognostic (2.02e-1)" "unprognostic (5.87e-2)" "unprognostic (4.89e-2)" "unprognostic (2.92e-3)" "unprognostic (1.31e-1)" "unprognostic (6.42e-3)" "unprognostic (7.24e-3)" "unprognostic (1.69e-1)" "unprognostic (7.42e-2)" "unprognostic (9.12e-2)" "unprognostic (1.00e-1)" "unprognostic (6.50e-3)" "unprognostic (2.47e-2)" "unprognostic (1.09e-1)" "unprognostic (5.47e-2)" "unprognostic (1.83e-1)" "unprognostic (9.18e-2)" "unprognostic (1.04e-2)" "unprognostic (5.56e-2)" "unprognostic (1.72e-1)" "unprognostic (2.10e-1)" "unprognostic (1.24e-1)" ALKBH7 "MGC10974, SPATA11" ENSG00000125652 "AlkB homolog 7" Q9BT30 19 6372794-6375250 "Predicted intracellular proteins" Necrosis "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 518.4" "Cell type enhanced" "Detected in many" "Early spermatids: 2931.5;Late primary spermatocytes: 3371.1;Late spermatids: 13356.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008539, HPA039571, HPA039872" Approved Supported Mitochondria NA NA "Cluster 18: Non-specific - Translation" "Cluster 35: Non-specific - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 23: Non-specific - Transcription" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 2 Mitochondria "HPA008539: , HPA039571: , HPA039872: " "unprognostic (2.71e-2)" "unprognostic (1.96e-1)" "unprognostic (1.32e-1)" "unprognostic (5.23e-2)" "unprognostic (1.26e-1)" "unprognostic (1.92e-1)" "unprognostic (1.60e-1)" "unprognostic (1.64e-1)" "unprognostic (1.85e-2)" "unprognostic (1.23e-1)" "unprognostic (4.57e-2)" "unprognostic (3.98e-2)" "potential prognostic favorable (9.37e-5)" "unprognostic (2.32e-1)" "unprognostic (3.03e-2)" "unprognostic (8.38e-2)" "unprognostic (7.66e-2)" "unprognostic (5.50e-2)" "unprognostic (2.03e-1)" "unprognostic (2.10e-1)" "unprognostic (1.10e-1)" "unprognostic (1.35e-3)" "unprognostic (9.79e-2)" "unprognostic (2.24e-2)" "unprognostic (7.80e-2)" "unprognostic (1.35e-1)" "unprognostic (3.17e-1)" "unprognostic (2.54e-2)" "unprognostic (1.78e-1)" "unprognostic (3.89e-2)" "unprognostic (2.95e-2)" ALKBH8 "MGC10235, TRM9, TRMT9A" ENSG00000137760 "AlkB homolog 8, tRNA methyltransferase" Q96BT7 11 107502727-107565742 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Methyltransferase, Multifunctional enzyme, RNA-binding, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 40.2;Sertoli cells: 56.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038724, HPA038725, HPA061514" Approved Supported "Nucleoplasm,Microtubules,Mitotic spindle,Primary cilium" Yes NA "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" 1 Nucleoplasm "Microtubules, Mitotic spindle, Primary cilium" "HPA038724: , HPA038725: , HPA061514: " "unprognostic (3.15e-2)" "unprognostic (4.31e-2)" "unprognostic (6.53e-2)" "unprognostic (7.44e-2)" "unprognostic (3.30e-2)" "unprognostic (2.72e-1)" "unprognostic (2.33e-2)" "unprognostic (4.51e-2)" "unprognostic (1.43e-1)" "potential prognostic unfavorable (8.65e-4)" "potential prognostic favorable (4.35e-5)" "unprognostic (1.49e-3)" "unprognostic (2.84e-1)" "unprognostic (2.51e-3)" "unprognostic (1.17e-1)" "unprognostic (2.03e-2)" "unprognostic (2.59e-2)" "unprognostic (2.13e-1)" "unprognostic (1.27e-1)" "unprognostic (5.15e-3)" "potential prognostic unfavorable (1.43e-4)" "unprognostic (1.72e-2)" "unprognostic (4.18e-2)" "unprognostic (6.22e-2)" "unprognostic (6.77e-3)" "unprognostic (2.52e-2)" "unprognostic (4.63e-3)" "unprognostic (2.71e-1)" "unprognostic (1.72e-1)" "unprognostic (7.23e-3)" "unprognostic (1.90e-1)" ALLC ALC ENSG00000151360 Allantoicase Q8N6M5 2 3658200-3702671 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 23 "testis: 15.6" "Cell type enhanced" "Detected in some" "Early spermatids: 178.5;Late primary spermatocytes: 93.4;Late spermatids: 42.0;Peritubular myoid cells: 16.5;Proximal tubule cells: 13.6" "Low cell type specificity" "Detected in some" "Not detected" "Not detected" "Region enriched" "Detected in single" 4 "choroid plexus: 2.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 23: Choroid plexus - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" "unprognostic (3.42e-3)" ALMS1 KIAA0328 ENSG00000116127 "ALMS1 centrosome and basal body associated protein" Q8TCU4 2 73385758-73625166 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Cone-rod dystrophy, Deafness, Diabetes mellitus, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 20.7" "Cell type enhanced" "Detected in many" "Respiratory ciliated cells: 258.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA035276, HPA043200" Enhanced Supported "Nucleoplasm,Microtubules,Centrosome,Basal body,Cytosol,Flagellar centriole,Mid piece,End piece" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 21: Testis - Mixed function" "Cluster 54: Immune cells - T cell receptor" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 7: Non-specific - Transcription" 17 "Centrosome, Basal body, Cytosol, Flagellar centriole" "Nucleoplasm, Microtubules, Mid piece, End piece" "HPA035276: , HPA043200: " "unprognostic (7.89e-3)" "unprognostic (2.49e-1)" "unprognostic (3.51e-1)" "unprognostic (5.93e-2)" "unprognostic (1.14e-1)" "unprognostic (5.51e-2)" "unprognostic (9.30e-2)" "unprognostic (7.07e-2)" "unprognostic (9.36e-2)" "unprognostic (1.39e-1)" "unprognostic (1.89e-3)" "unprognostic (5.55e-2)" "unprognostic (2.40e-1)" "potential prognostic unfavorable (9.26e-6)" "unprognostic (2.92e-2)" "unprognostic (4.78e-2)" "unprognostic (1.31e-1)" "unprognostic (2.20e-2)" "unprognostic (7.87e-3)" "unprognostic (5.33e-2)" "unprognostic (5.92e-2)" "unprognostic (1.60e-1)" "unprognostic (4.56e-3)" "unprognostic (3.53e-1)" "unprognostic (2.38e-3)" "unprognostic (1.35e-3)" "unprognostic (3.35e-2)" "unprognostic (1.09e-1)" "unprognostic (3.72e-2)" "unprognostic (4.83e-3)" "unprognostic (7.24e-2)" ALOX12 12S-LOX ENSG00000108839 "Arachidonate 12-lipoxygenase, 12S type" P18054 17 6996049-7010754 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Dioxygenase, Hydrolase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 78.6;esophagus: 47.5;vagina: 95.8" "Group enriched" "Detected in many" 6 "Esophageal apical cells: 321.2;Megakaryocytes: 265.8;Platelets: 364.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in single" 5 "olfactory bulb: 4.4" "Low region specificity" "Detected in all" "HPA010691, CAB019287, HPA064819" Enhanced Supported Cytosol NA NA 280000 "Cluster 35: Neutrophils - Protein binding" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 11: White matter - Signal transduction" "Cluster 47: Leukemia - Hemostasis" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 7 Cytosol "CAB019287: , HPA010691: , HPA064819: " "potential prognostic unfavorable (2.50e-4)" "unprognostic (7.08e-2)" "unprognostic (5.88e-3)" "unprognostic (2.51e-1)" "unprognostic (8.77e-2)" "unprognostic (1.18e-1)" "unprognostic (1.56e-2)" "unprognostic (1.95e-1)" "unprognostic (1.23e-1)" "unprognostic (2.92e-1)" "unprognostic (2.33e-1)" "unprognostic (3.80e-2)" "unprognostic (3.90e-1)" "unprognostic (1.02e-1)" "unprognostic (1.58e-1)" "unprognostic (6.85e-3)" "unprognostic (4.59e-3)" "unprognostic (2.02e-2)" "unprognostic (1.18e-2)" "unprognostic (2.59e-2)" "unprognostic (2.63e-1)" "unprognostic (3.26e-2)" ALOX12B 12R-LOX ENSG00000179477 "Arachidonate 12-lipoxygenase, 12R type" O75342 17 8072636-8087716 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Dioxygenase, Isomerase, Lyase, Oxidoreductase" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "skin 1: 89.6" "Cell type enriched" "Detected in some" 4 "Tuft cells: 69.2" "Cell type enhanced" "Detected in many" "midbrain-derived inhibitory: 4.1" "Group enriched" "Detected in some" 6 "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 4.8;Head and Neck Squamous Cell Carcinoma (TCGA): 18.8;Skin Cutaneous Melanoma (TCGA): 9.1" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 6 "basophil: 4.3" "Lineage enriched" "Detected in single" 6 "granulocytes: 4.3" "Cancer enhanced" "Detected in some" "cervical cancer: 3.2" "Prostate - Prostate glandular cells, Skin - Keratinocyte (granular), Spleen - B-cells (Spleen)" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA024002 Supported Supported Vesicles,Cytosol NA NA 140000 "Cluster 32: Basophils - Transcription" "Cluster 37: Skin - Keratinization" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 31 Cytosol Vesicles "HPA024002: " "unprognostic (8.99e-2)" "potential prognostic favorable (8.73e-5)" "unprognostic (3.37e-3)" "unprognostic (1.78e-2)" "unprognostic (2.68e-2)" "unprognostic (1.25e-1)" "unprognostic (8.07e-2)" "unprognostic (2.67e-1)" ALOX15 15-LOX-1 ENSG00000161905 "Arachidonate 15-lipoxygenase" P16050 17 4630919-4642294 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 35.2;fallopian tube: 12.0" "Cell type enhanced" "Detected in some" "cDC: 35.2;Conjunctival goblet cells: 28.2;Epicardial cells: 45.5;Mesothelial cells: 106.1;Respiratory basal cells: 119.7;Respiratory ciliated cells: 277.9;Respiratory deuterosomal cells: 121.3;Respiratory secretory cells: 142.6" "Cell type enhanced" "Detected in some" "medium spiny neuron: 2.5" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 13.6;Lung Squamous Cell Carcinoma (TCGA): 13.2" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 194 "eosinophil: 608.0" "Lineage enriched" "Detected in many" 194 "granulocytes: 608.0" "Cancer enhanced" "Detected in some" "prostate cancer: 24.6" "Adipose visceral - Mesothelial cells, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Not detected" "Not detected" "Region enhanced" "Detected in all" "hippocampal formation: 18.6" "CAB004962, CAB004963, HPA013859" Approved NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 33: Neurons - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 5 "CAB004962: , CAB004963: , HPA013859: " "unprognostic (2.93e-2)" "potential prognostic unfavorable (7.12e-5)" "unprognostic (1.45e-1)" "potential prognostic favorable (1.57e-4)" "unprognostic (9.93e-2)" "unprognostic (5.56e-2)" "unprognostic (1.34e-1)" "unprognostic (6.93e-3)" "unprognostic (2.46e-3)" "unprognostic (1.71e-1)" "unprognostic (2.51e-2)" "unprognostic (1.13e-1)" "unprognostic (3.24e-1)" "unprognostic (4.46e-3)" "unprognostic (3.77e-1)" "unprognostic (5.45e-2)" "unprognostic (1.02e-1)" ALOX15B 15-LOX-2 ENSG00000179593 "Arachidonate 15-lipoxygenase type B" O15296 17 8039034-8049134 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 105.2;prostate: 68.6" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 250.9;Breast hormone-responsive cells: 50.9;Conjunctival goblet cells: 71.8;Esophageal apical cells: 70.6;Esophageal basal cells: 46.9;Esophageal suprabasal cells: 127.5;Kupffer cells: 30.7;Macrophages: 30.9;Monocyte progenitors: 50.9;Ocular epithelial cells: 41.7;Prostatic glandular cells: 100.1;Transitional alveolar cells: 63.9" "Cell type enhanced" "Detected in single" "central nervous system macrophage: 2.0" "Cancer enriched" "Detected in many" 4 "Prostate Adenocarcinoma (TCGA): 140.1" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 8 "classical monocyte: 3.9;myeloid DC: 4.3" "Group enriched" "Detected in many" 8 "dendritic cells: 4.3;monocytes: 3.9" "Cancer enriched" "Detected in some" 10 "breast cancer: 26.1" "Adrenal gland - Macrophages, Breast - Breast glandular cells, Kidney - Macrophages, Pancreas - Macrophages, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA010562 Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 30: White matter - Myelination" "Cluster 27: Breast cancer - Unknown function" "Cluster 81: Alveolar cells - Lung function" 7 "Plasma membrane, Cytosol" "HPA010562: " "unprognostic (9.30e-3)" "unprognostic (3.06e-2)" "unprognostic (7.88e-2)" "unprognostic (1.46e-1)" "unprognostic (3.38e-1)" "unprognostic (4.02e-2)" "unprognostic (8.18e-3)" "unprognostic (2.34e-3)" "unprognostic (5.57e-2)" "unprognostic (1.07e-1)" "unprognostic (4.32e-2)" "potential prognostic favorable (2.15e-5)" "unprognostic (1.75e-1)" "unprognostic (1.08e-1)" "unprognostic (3.62e-2)" "unprognostic (2.08e-1)" "unprognostic (3.79e-2)" "unprognostic (8.89e-2)" "unprognostic (5.58e-2)" "unprognostic (1.59e-3)" "unprognostic (4.96e-2)" "unprognostic (2.76e-2)" "unprognostic (3.74e-1)" "unprognostic (4.94e-2)" "unprognostic (2.71e-2)" "unprognostic (9.23e-2)" "unprognostic (3.50e-2)" "unprognostic (3.03e-1)" "unprognostic (2.61e-2)" ALOX5 5-LOX ENSG00000012779 "Arachidonate 5-lipoxygenase" P09917 10 45374176-45446119 "Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Leukotriene biosynthesis, Lipid metabolism" "Dioxygenase, Hydrolase, Oxidoreductase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 69.4;lymphoid tissue: 90.4" "Group enriched" "Detected in some" 6 "Microglia: 280.8;Papillary tip epithelial cells: 131.7;Tuft cells: 322.8" "Cell type enriched" "Detected in many" 6 "central nervous system macrophage: 355.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "lymphoma: 26.3;pancreatic cancer: 12.6" "Adipose subcutaneous - Macrophages, Adrenal gland - Macrophages, Breast - Breast glandular cells, Colon - Macrophages, Liver - Neutrophils, Pituitary gland - Macrophages, Spleen - Neutrophils_2, Stomach - Macrophages, Thyroid gland - Macrophages" "Region enriched" "Detected in single" 4 "white matter: 2.9" "Low region specificity" "Detected in all" HPA071285 Enhanced Supported Nucleoplasm NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 5: Spleen - Immune response" "Cluster 25: Non-specific - Transcription" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 21 Nucleoplasm "HPA071285: " "unprognostic (6.67e-3)" "unprognostic (5.50e-3)" "unprognostic (9.23e-2)" "unprognostic (2.06e-1)" "unprognostic (1.01e-1)" "unprognostic (1.59e-1)" "unprognostic (1.44e-2)" "unprognostic (4.22e-1)" "unprognostic (1.62e-1)" "unprognostic (2.22e-1)" "unprognostic (1.57e-2)" "unprognostic (1.98e-1)" "unprognostic (4.56e-3)" "potential prognostic unfavorable (1.86e-4)" "unprognostic (4.00e-2)" "unprognostic (1.19e-1)" "unprognostic (1.95e-2)" "unprognostic (2.80e-2)" "unprognostic (9.16e-2)" "unprognostic (2.64e-2)" "unprognostic (7.18e-2)" "unprognostic (6.69e-2)" "unprognostic (1.97e-2)" "unprognostic (4.34e-1)" "unprognostic (2.22e-1)" "unprognostic (1.11e-1)" "unprognostic (2.59e-2)" "unprognostic (1.71e-1)" "unprognostic (2.98e-3)" "unprognostic (2.44e-2)" "unprognostic (9.11e-2)" ALOX5AP FLAP ENSG00000132965 "Arachidonate 5-lipoxygenase activating protein" P20292 13 30713478-30764426 "Disease related genes, Predicted membrane proteins" "Leukotriene biosynthesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 460.3;lung: 172.6;lymphoid tissue: 141.7" "Cell type enhanced" "Detected in many" "Hofbauer cells: 559.5;Macrophages: 379.2;Mast cells: 942.5;Neutrophil progenitors: 1950.0;Neutrophils: 3928.7;pDCs: 774.7;Tuft cells: 392.0" "Group enriched" "Detected in some" 43 "central nervous system macrophage: 118.7;leukocyte: 85.5" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 176.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "basophil: 9738.9;eosinophil: 4044.4;neutrophil: 4992.0;plasmacytoid DC: 3563.5" "Group enriched" "Detected in all" 8 "dendritic cells: 3563.5;granulocytes: 9738.9" "Cancer enhanced" "Detected in many" "Leukemia: 124.7;lymphoma: 190.4" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Neutrophils, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Spleen - Neutrophils_2, Stomach - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026592 Enhanced NA NA "Cluster 41: Basophils - Unknown function" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 6 "HPA026592: " "unprognostic (1.44e-2)" "unprognostic (1.53e-2)" "unprognostic (1.77e-1)" "unprognostic (1.73e-1)" "unprognostic (3.47e-1)" "unprognostic (7.28e-2)" "unprognostic (3.36e-2)" "unprognostic (6.88e-2)" "unprognostic (5.98e-2)" "potential prognostic unfavorable (1.91e-4)" "unprognostic (3.36e-3)" "unprognostic (9.85e-3)" "unprognostic (1.24e-1)" "unprognostic (6.71e-2)" "unprognostic (4.22e-1)" "unprognostic (3.55e-2)" "unprognostic (3.81e-2)" "unprognostic (3.91e-2)" "unprognostic (3.51e-3)" "unprognostic (2.02e-3)" "unprognostic (2.47e-2)" "unprognostic (7.24e-2)" "unprognostic (1.94e-1)" "unprognostic (3.36e-2)" "unprognostic (3.73e-2)" "unprognostic (4.01e-2)" "unprognostic (4.45e-2)" "unprognostic (1.61e-1)" "unprognostic (4.43e-2)" "unprognostic (2.06e-2)" "unprognostic (3.23e-3)" ALOXE3 "E-LOX, eLOX3" ENSG00000179148 "Arachidonate lipoxygenase 3" Q9BYJ1 17 8095900-8119047 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Dioxygenase, Isomerase, Lyase, Oxidoreductase" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 22 "skin 1: 53.8" "Cell type enriched" "Detected in some" 4 "Oocytes: 64.5" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 5.9" "Cancer enhanced" "Detected in some" "Head and Neck Squamous Cell Carcinoma (TCGA): 4.6;Skin Cutaneous Melanoma (TCGA): 2.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Prostate - Prostate basal glandular cells, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA023120, HPA078597" Enhanced Approved "Plasma membrane,Cytosol" NA NA 49000 "Cluster 37: Skin - Keratinization" "Cluster 37: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 41: Oocytes - Oogenesis" 9 "Plasma membrane, Cytosol" "HPA023120: , HPA078597: " "unprognostic (7.05e-2)" "unprognostic (4.33e-2)" "potential prognostic favorable (1.78e-4)" "unprognostic (2.41e-2)" "unprognostic (2.00e-1)" ALPG "ALPPL2, GCAP" ENSG00000163286 "Alkaline phosphatase, germ cell" P10696 2 232406844-232410714 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 1.4;Colonocytes: 1.3;Differentiating spermatogonia: 1.1;Endometrial luminal cells: 1.2;Gastric progenitor cells: 2.6;Transitional alveolar cells: 1.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 100.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 20.0;testis cancer: 35.3" "CAB020698, HPA038764, HPA038765, HPA051699" Approved Approved "Plasma membrane" "Intracellular and membrane" Enzyme NA NA "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 13 "Plasma membrane" "CAB020698: , HPA038764: , HPA038765: , HPA051699: " "unprognostic (5.07e-1)" "unprognostic (8.06e-2)" "unprognostic (1.42e-2)" "unprognostic (4.44e-2)" "unprognostic (7.13e-2)" "unprognostic (1.42e-2)" "unprognostic (8.34e-2)" "unprognostic (1.53e-2)" "potential prognostic unfavorable (5.30e-4)" "unprognostic (1.14e-1)" "unprognostic (3.39e-2)" "unprognostic (2.99e-2)" "unprognostic (8.51e-2)" "unprognostic (2.89e-1)" "unprognostic (1.99e-1)" ALPI IAP ENSG00000163295 "Alkaline phosphatase, intestinal" P09923 2 232456125-232460753 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 139 "intestine: 133.1" "Cell type enriched" "Detected in some" 11 "Enterocytes: 326.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney Renal Clear Cell Carcinoma (TCGA): 5.2;Liver Hepatocellular Carcinoma (TCGA): 4.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enterocytes" "HPA038764, HPA038765, HPA051699" Supported Approved "Plasma membrane" "Intracellular and membrane" Enzyme NA NA 350000 "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 34: Testis cancer - Unknown function" "Cluster 1: Enterocytes - Absorption and Digestion" 36 "Plasma membrane" "HPA038764: , HPA038765: , HPA051699: " "unprognostic (1.59e-1)" "unprognostic (5.40e-3)" "unprognostic (2.01e-1)" "unprognostic (9.35e-2)" "unprognostic (2.24e-2)" "unprognostic (3.38e-3)" "unprognostic (9.97e-2)" "unprognostic (2.34e-2)" ALPK1 "FLJ22670, KIAA1527, Lak" ENSG00000073331 "Alpha kinase 1" Q96QP1 4 112285509-112442621 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation, Immunity, Innate immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Neutrophil progenitors: 733.4;Neutrophils: 1465.8" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 267.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 18.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Spleen - Neutrophils_2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA027435, HPA027443" Approved Supported "Centrosome,Basal body" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 49: Non-specific - Transcription" "Cluster 29: Forebrain - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 1 "Centrosome, Basal body" "HPA027435: , HPA027443: " "unprognostic (1.49e-2)" "unprognostic (6.80e-2)" "unprognostic (6.04e-2)" "unprognostic (2.52e-1)" "unprognostic (5.58e-2)" "unprognostic (4.80e-2)" "unprognostic (2.00e-1)" "unprognostic (4.19e-1)" "unprognostic (5.49e-2)" "potential prognostic unfavorable (3.25e-4)" "unprognostic (5.12e-2)" "unprognostic (3.47e-2)" "unprognostic (8.12e-2)" "unprognostic (5.89e-2)" "unprognostic (4.69e-3)" "unprognostic (1.05e-1)" "unprognostic (5.41e-2)" "unprognostic (1.01e-2)" "unprognostic (3.49e-2)" "unprognostic (1.60e-1)" "unprognostic (1.28e-1)" "unprognostic (7.00e-3)" "potential prognostic unfavorable (9.06e-4)" "unprognostic (1.31e-1)" "potential prognostic favorable (7.25e-4)" "unprognostic (3.35e-2)" "unprognostic (5.49e-2)" "unprognostic (1.33e-1)" "unprognostic (3.84e-2)" "unprognostic (1.93e-1)" "unprognostic (2.33e-2)" ALPK2 HAK ENSG00000198796 "Alpha kinase 2" Q86TB3 18 58481247-58629091 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 39.2;skeletal muscle: 35.9;tongue: 31.0" "Group enriched" "Detected in many" 5 "Cardiomyocytes: 373.6;Cone photoreceptor cells: 101.4;Myonuclei: 373.2;Proximal tubule cells: 223.6" "Cell type enhanced" "Detected in some" "hippocampal dentate gyrus: 4.2" "Group enriched" "Detected in some" 7 "Kidney Renal Clear Cell Carcinoma (TCGA): 20.0;Kidney Renal Papillary Cell Carcinoma (TCGA): 9.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 35.2" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Cardiomyocytes, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA027377, HPA027976, HPA028084, HPA029801" Uncertain Approved Cytosol NA NA "Cluster 41: Striated muscle - Muscle contraction" "Cluster 15: Kidney cancer - Membrane components" "Cluster 55: Myocytes - Oxidative muscle function" Cytosol "HPA027377: , HPA027976: , HPA028084: , HPA029801: " "unprognostic (1.81e-1)" "unprognostic (9.21e-2)" "unprognostic (2.59e-2)" "unprognostic (9.72e-2)" "unprognostic (2.54e-1)" "unprognostic (3.55e-2)" "unprognostic (1.16e-2)" "unprognostic (6.64e-2)" "unprognostic (1.17e-1)" "unprognostic (1.98e-2)" "unprognostic (3.87e-1)" "unprognostic (7.22e-2)" "unprognostic (1.76e-2)" "unprognostic (2.63e-2)" ALPK3 "KIAA1330, MAK, Midori" ENSG00000136383 "Alpha kinase 3" Q96L96 15 84817356-84873479 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 62.2;skeletal muscle: 198.3;tongue: 55.2" "Cell type enhanced" "Detected in many" "Adipocytes: 116.6;Cardiomyocytes: 219.0;Lactotrophs: 193.5;Myonuclei: 774.4;Pancreatic islet cells: 110.5;Somatotrophs: 229.3;Thymic myoid cells: 184.9;Thyrotrophs: 181.4" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 77.2;vascular associated smooth muscle cell: 65.0" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 21.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 9.6" "Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA026558 Uncertain Approved Nucleoplasm NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 44: Non-specific - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" Nucleoplasm "HPA026558: " "unprognostic (4.50e-2)" "unprognostic (5.28e-2)" "unprognostic (1.37e-1)" "unprognostic (3.07e-1)" "unprognostic (7.28e-2)" "unprognostic (1.32e-1)" "unprognostic (2.31e-1)" "unprognostic (4.03e-2)" "unprognostic (8.68e-2)" "unprognostic (1.50e-2)" "validated prognostic favorable (4.60e-4)" "validated prognostic favorable (6.73e-6)" "potential prognostic favorable (4.10e-4)" "unprognostic (1.21e-3)" "unprognostic (1.64e-2)" "unprognostic (4.60e-2)" "unprognostic (3.24e-2)" "unprognostic (4.07e-2)" "unprognostic (8.05e-2)" "unprognostic (2.68e-1)" "unprognostic (2.76e-2)" "unprognostic (3.06e-3)" "unprognostic (1.60e-2)" "unprognostic (3.76e-1)" "unprognostic (1.69e-1)" "unprognostic (7.01e-2)" "unprognostic (3.18e-2)" "unprognostic (2.10e-1)" "unprognostic (8.60e-2)" "unprognostic (5.50e-2)" ALPL "HOPS, TNALP, TNAP, TNSALP" ENSG00000162551 "Alkaline phosphatase, biomineralization associated" P05186 1 21509397-21578410 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Biomineralization Hydrolase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 57.7" "Group enriched" "Detected in many" 5 "Alveolar cells type 2: 811.1;Neutrophils: 1574.3" "Cell type enriched" "Detected in many" 7 "endothelial cell: 166.4" "Cancer enriched" "Detected in all" 4 "Testicular Germ Cell Tumor (TCGA): 292.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 90 "neutrophil: 381.2" "Lineage enriched" "Detected in many" 139 "granulocytes: 381.2" "Cancer enhanced" "Detected in many" "Bone cancer: 75.0;testis cancer: 44.3" "Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Prostate - Macrophages, Skeletal muscle - Neutrophils, Spleen - Neutrophils_2, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007105, HPA008765, CAB020829" Enhanced Approved Cytosol "Intracellular and membrane" Enzyme NA NA 9400000 "Cluster 4: Neutrophils - Degranulation" "Cluster 5: Spleen - Immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 24: Neutrophils - Innate immunity signal integration" 1 Cytosol "CAB020829: , HPA007105: , HPA008765: " "unprognostic (7.68e-2)" "unprognostic (4.91e-2)" "unprognostic (1.50e-1)" "unprognostic (1.14e-2)" "unprognostic (9.58e-2)" "unprognostic (5.72e-2)" "unprognostic (1.37e-3)" "unprognostic (2.75e-1)" "unprognostic (2.21e-2)" "unprognostic (2.40e-3)" "validated prognostic favorable (3.12e-4)" "validated prognostic favorable (5.51e-5)" "unprognostic (1.29e-1)" "unprognostic (5.58e-3)" "potential prognostic favorable (1.20e-4)" "unprognostic (4.70e-2)" "unprognostic (1.33e-1)" "potential prognostic unfavorable (2.22e-4)" "unprognostic (7.24e-2)" "unprognostic (5.17e-2)" "unprognostic (2.43e-2)" "unprognostic (1.03e-2)" "unprognostic (2.30e-1)" "unprognostic (2.40e-1)" "unprognostic (9.49e-2)" "unprognostic (1.28e-1)" "unprognostic (9.06e-2)" "unprognostic (1.42e-2)" "unprognostic (1.72e-1)" "unprognostic (6.75e-3)" "unprognostic (4.14e-2)" ALPP "PALP, PLAP" ENSG00000163283 "Alkaline phosphatase, placental" P05187 2 232378724-232382889 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "cervix: 16.7;placenta: 32.6" "Group enriched" "Detected in some" 6 "Alveolar cells type 1: 67.7;Endometrial secretory cells: 74.9;Transitional alveolar cells: 21.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 13.3;Uterine Corpus Endometrial Carcinoma (TCGA): 15.6" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Esophageal cancer: 48.0;Gastric cancer: 52.3" "CAB026327, HPA038764, HPA038765, HPA051699" Enhanced Approved "Plasma membrane" "Intracellular and membrane" Enzyme NA NA 3300000 "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 81: Alveolar cells - Lung function" 57 "Plasma membrane" "CAB026327: , HPA038764: , HPA038765: , HPA051699: " "unprognostic (1.00e-1)" "unprognostic (6.01e-2)" "unprognostic (9.47e-2)" "unprognostic (1.05e-2)" "unprognostic (6.56e-2)" "unprognostic (2.33e-1)" "potential prognostic unfavorable (3.17e-4)" "unprognostic (1.09e-2)" "unprognostic (3.41e-1)" "unprognostic (1.81e-1)" "unprognostic (1.45e-1)" ALS2 ALS2CR6 ENSG00000003393 "Alsin Rho guanine nucleotide exchange factor ALS2" Q96Q42 2 201700267-201782112 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Amyotrophic lateral sclerosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 21.3" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 167.4;Choroid plexus epithelial cells: 147.5;Hematopoietic stem cells: 202.8;Mast cells: 145.8;Somatotrophs: 133.1" "Cell type enhanced" "Detected in all" "upper rhombic lip: 396.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 22.8;eosinophil: 6.8" "Lineage enriched" "Detected in all" 7 "granulocytes: 22.8" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "cerebellum: 129.9" "HPA046588, HPA075409" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 27: Cerebellum - Synaptic function" "Cluster 35: Non-specific - DNA binding" "Cluster 49: HMC-1 - Innate immune response" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 20 "Vesicles, Cytosol" "HPA046588: , HPA075409: " "unprognostic (1.94e-2)" "unprognostic (2.02e-1)" "unprognostic (1.40e-2)" "unprognostic (9.09e-2)" "unprognostic (9.18e-2)" "unprognostic (9.05e-2)" "unprognostic (2.19e-1)" "unprognostic (1.67e-1)" "unprognostic (8.22e-3)" "unprognostic (8.48e-3)" "potential prognostic favorable (3.78e-4)" "unprognostic (3.69e-2)" "potential prognostic unfavorable (4.06e-4)" "unprognostic (5.43e-3)" "unprognostic (3.91e-1)" "unprognostic (6.11e-2)" "unprognostic (1.50e-1)" "unprognostic (1.07e-1)" "unprognostic (9.74e-3)" "unprognostic (4.59e-1)" "unprognostic (2.75e-1)" "unprognostic (1.16e-1)" "potential prognostic unfavorable (4.64e-4)" "unprognostic (1.74e-1)" "unprognostic (8.42e-2)" "unprognostic (2.48e-1)" "unprognostic (1.42e-1)" "unprognostic (2.18e-1)" "unprognostic (1.49e-1)" "unprognostic (1.44e-1)" "unprognostic (5.79e-2)" ALS2CL "DKFZp686I0110, FLJ36525, RN49018" ENSG00000178038 "ALS2 C-terminal like" Q60I27 3 46668995-46693704 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 35.3;kidney: 31.5;skin 1: 31.1" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 409.1;Esophageal suprabasal cells: 218.8;Podocytes: 1308.6" "Cell type enhanced" "Detected in many" "endothelial cell: 41.2;pericyte: 21.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 30.5" "Kidney - Podocytes, Prostate - Urothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB046465, HPA048301" Uncertain NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 58: Skin - Keratinization" "Cluster 37: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 57: Podocytes - Glomerular filtration" 5 "CAB046465: , HPA048301: " "unprognostic (2.69e-2)" "unprognostic (1.18e-1)" "unprognostic (2.82e-2)" "unprognostic (2.92e-2)" "unprognostic (6.76e-2)" "unprognostic (2.31e-3)" "potential prognostic unfavorable (5.11e-4)" "unprognostic (6.71e-2)" "unprognostic (9.22e-2)" "unprognostic (8.40e-2)" "unprognostic (1.68e-2)" "unprognostic (6.81e-3)" "unprognostic (3.61e-1)" "unprognostic (1.75e-2)" "unprognostic (1.69e-1)" "unprognostic (1.27e-1)" "unprognostic (2.36e-3)" "unprognostic (3.69e-2)" "unprognostic (5.87e-2)" "unprognostic (6.53e-3)" "unprognostic (2.33e-2)" "unprognostic (3.26e-1)" "unprognostic (8.01e-3)" "unprognostic (1.81e-2)" "unprognostic (2.16e-2)" "unprognostic (4.47e-2)" "unprognostic (3.90e-2)" "unprognostic (1.54e-1)" ALX1 CART1 ENSG00000180318 "ALX homeobox 1" Q15699 12 85280220-85301784 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 3.7;kidney: 7.1" "Cell type enriched" "Detected in some" 13 "Melanocytes: 113.2" "Cell type enhanced" "Detected in some" "ependymal cell: 1.4;fibroblast: 2.3;pericyte: 2.5" "Cancer enriched" "Detected in some" 10 "Skin Cutaneous Melanoma (TCGA): 30.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 19.3" "Kidney - Fibroblasts, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001598, HPA018905" Uncertain Supported "Nucleoplasm,Nuclear bodies,Golgi apparatus" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 69: Skin cancer - ECM organization" "Cluster 61: Schwann cells & Melanocytes - Mixed function" 11 "Nuclear bodies" "Nucleoplasm, Golgi apparatus" "HPA001598: , HPA018905: " "unprognostic (5.46e-2)" "unprognostic (9.66e-2)" "unprognostic (3.11e-2)" "unprognostic (4.57e-2)" "unprognostic (8.79e-2)" ALX3 FND ENSG00000156150 "ALX homeobox 3" O95076 1 110059870-110070672 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 6.8" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 10.4;Epicardial cells: 13.6;Fibroblasts: 2.5;Mesothelial cells: 2.4;Oocytes: 13.8;Pericytes: 3.3;Rod photoreceptor cells: 2.5" "Group enriched" "Detected in some" 4 "fibroblast: 9.4;pericyte: 6.2;vascular associated smooth muscle cell: 10.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Pituitary gland - Fibroblasts" "Region enriched" "Detected in many" 8 "olfactory bulb: 16.7" "Low region specificity" "Detected in single" HPA074290 Approved "Nucleoli fibrillar center" NA NA "Cluster 40: Non-specific - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 22: Non-specific - Basic cellular functions" "Nucleoli fibrillar center" "HPA074290: " "unprognostic (7.28e-2)" "unprognostic (5.59e-2)" "unprognostic (1.86e-2)" "unprognostic (4.32e-2)" "unprognostic (4.95e-2)" "unprognostic (1.23e-1)" "unprognostic (2.49e-2)" "potential prognostic unfavorable (6.69e-4)" "unprognostic (6.30e-3)" "unprognostic (7.51e-2)" "unprognostic (1.60e-2)" "unprognostic (1.84e-3)" "unprognostic (4.37e-3)" "unprognostic (7.27e-3)" "unprognostic (7.30e-2)" "unprognostic (1.64e-1)" "unprognostic (4.02e-2)" "unprognostic (1.63e-1)" "unprognostic (4.60e-3)" "unprognostic (1.93e-1)" "potential prognostic favorable (1.42e-4)" "unprognostic (1.59e-1)" "unprognostic (1.07e-1)" "unprognostic (2.35e-1)" "unprognostic (7.53e-2)" "unprognostic (1.87e-2)" "unprognostic (8.43e-2)" "unprognostic (1.11e-1)" "unprognostic (2.08e-1)" ALX4 "FPP, KIAA1788, PFM, PFM2" ENSG00000052850 "ALX homeobox 4" Q9H161 11 44260440-44310139 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 1.7;choroid plexus: 1.5" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 5.1;Choroid plexus epithelial cells: 8.9;Ependymal cells: 17.1;Epicardial cells: 15.9;Fibro-adipogenic progenitors: 4.1;Fibroblasts: 7.2;Leydig cells: 16.7;Myosatellite cells: 17.0;Vascular smooth muscle cells: 4.0" "Cell type enhanced" "Detected in some" "ependymal cell: 14.8;fibroblast: 39.6;vascular associated smooth muscle cell: 15.0" "Cancer enhanced" "Detected in single" "Testicular Germ Cell Tumor (TCGA): 2.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "Bone cancer: 20.7" "Region enriched" "Detected in some" 8 "olfactory bulb: 9.0" "Region enriched" "Detected in single" 28 "olfactory bulb: 12.1" HPA001903 Supported Nucleoplasm NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 65: Non-specific - Unknown function" "Cluster 108: Fibroblasts - ECM organization" 2 Nucleoplasm "HPA001903: " "unprognostic (1.81e-1)" "unprognostic (2.06e-1)" "unprognostic (2.02e-1)" ALYREF "ALY, ALY/REF, BEF, REF, THOC4" ENSG00000183684 "Aly/REF export factor" 17 81887835-81891586 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 140.5" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 160.3;Megakaryocyte progenitors: 90.3;Megakaryocytes: 98.9;Monocyte progenitors: 93.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016281, HPA019799, HPA061282" Supported Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 27: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 17: Non-specific - RNA processing" 86 "Nucleoplasm, Nuclear speckles" "CAB016281: , HPA019799: , HPA061282: " "unprognostic (3.55e-2)" "unprognostic (2.03e-1)" "unprognostic (7.22e-2)" "unprognostic (2.40e-2)" "unprognostic (4.55e-1)" "unprognostic (1.69e-1)" "unprognostic (8.14e-3)" "unprognostic (2.84e-2)" "unprognostic (1.84e-2)" "unprognostic (1.05e-1)" "unprognostic (1.93e-1)" "unprognostic (1.49e-3)" "potential prognostic unfavorable (1.39e-4)" "unprognostic (1.69e-3)" "potential prognostic unfavorable (2.19e-6)" "unprognostic (2.32e-1)" "unprognostic (4.67e-2)" "unprognostic (8.61e-3)" "unprognostic (6.07e-3)" "unprognostic (1.28e-1)" "unprognostic (3.07e-2)" "unprognostic (4.40e-3)" "unprognostic (4.08e-2)" "unprognostic (2.40e-2)" "unprognostic (2.20e-1)" "unprognostic (1.09e-2)" "unprognostic (2.11e-1)" "unprognostic (5.96e-2)" "unprognostic (2.70e-1)" AMACR "P504S, RACE" ENSG00000242110 "Alpha-methylacyl-CoA racemase" Q9UHK6 5 33986165-34008104 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Isomerase "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 124.7;liver: 167.6" "Cell type enhanced" "Detected in many" "Bergmann glia: 14.3;Brain inhibitory neurons: 9.3;Cholangiocytes: 9.9;Colonocytes: 12.3;Ependymal cells: 12.2;Hepatocytes: 24.7;Microglia: 13.7;Oligodendrocyte progenitor cells: 10.2;Other brain neurons: 14.7;Respiratory ionocytes: 15.2" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Kidney Renal Papillary Cell Carcinoma (TCGA): 398.6;Prostate Adenocarcinoma (TCGA): 456.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Stomach - Chief cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "CAB001809, HPA019527, HPA020912" Enhanced Supported "Vesicles,Peroxisomes,Plasma membrane,Cytosol" NA NA 35000 "Cluster 21: Neutrophils - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 1: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" "Vesicles, Peroxisomes" "Plasma membrane, Cytosol" "CAB001809: , HPA019527: , HPA020912: " "unprognostic (1.91e-1)" "unprognostic (1.13e-1)" "unprognostic (1.97e-1)" "unprognostic (1.12e-1)" "unprognostic (7.60e-2)" "unprognostic (1.02e-1)" "unprognostic (2.39e-1)" "unprognostic (1.84e-2)" "unprognostic (5.90e-3)" "potential prognostic unfavorable (6.85e-4)" "unprognostic (3.51e-3)" "unprognostic (1.50e-2)" "unprognostic (1.61e-2)" "unprognostic (2.31e-1)" "unprognostic (2.36e-1)" "unprognostic (8.78e-2)" "unprognostic (3.06e-1)" "unprognostic (1.21e-1)" "unprognostic (1.07e-2)" "unprognostic (1.20e-1)" "unprognostic (6.01e-2)" "potential prognostic favorable (1.56e-4)" "unprognostic (2.05e-1)" "unprognostic (1.48e-2)" "unprognostic (7.38e-3)" "unprognostic (3.43e-1)" "unprognostic (1.68e-1)" "unprognostic (1.06e-1)" "unprognostic (2.61e-1)" "unprognostic (7.19e-2)" "unprognostic (2.97e-1)" AMBN ENSG00000178522 Ameloblastin Q9NP70 4 70592256-70607288 "Disease related genes, Human disease related genes, Predicted secreted proteins" Biomineralization "Amelogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 2.9" "Cell type enhanced" "Detected in single" "pDCs: 1.8" "Cell type enhanced" "Detected in some" "eccentric medium spiny neuron: 1.2;medium spiny neuron: 2.1" "Group enriched" "Detected in some" 13 "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 5.5;Uterine Corpus Endometrial Carcinoma (TCGA): 5.3" "Region enhanced" "Detected in single" "basal ganglia: 2.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "colorectal cancer: 2.5;Rhabdoid: 7.4" "Skin - Inner root sheath cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA036099 Uncertain Nucleoplasm,Vesicles "Secreted in other tissues" Other NA NA 17000 "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 5 Vesicles Nucleoplasm "HPA036099: " "unprognostic (7.37e-1)" AMBP "EDC1, HCP, HI30, IATIL, ITI, ITIL, ITILC, UTI" ENSG00000106927 "Alpha-1-microglobulin/bikunin precursor" P02760 9 114060127-114078328 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction" "Oxidoreductase, Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 68 "liver: 10227.4" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 12897.0" "Cell type enriched" "Detected in some" 7 "ependymal cell: 10.4" "Cancer enriched" "Detected in many" 107 "Liver Hepatocellular Carcinoma (TCGA): 5486.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 8 "liver cancer: 556.5" "Breast - Breast glandular cells, Liver - Hepatocytes, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA001497, CAB069436, HPA075585" Approved Approved "Golgi apparatus,Vesicles,Cytosol" "Secreted to blood" Enzyme NA NA 3300000000 29000000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 18: Liver cancer - Metabolism" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 4 Vesicles "Golgi apparatus, Cytosol" "CAB069436: , HPA001497: , HPA075585: " "unprognostic (3.63e-3)" "unprognostic (8.63e-2)" "unprognostic (8.75e-3)" "unprognostic (2.74e-1)" "unprognostic (4.05e-2)" "unprognostic (3.78e-3)" "unprognostic (1.56e-1)" "unprognostic (2.52e-3)" "unprognostic (6.70e-3)" "unprognostic (2.61e-2)" "unprognostic (1.08e-2)" "unprognostic (3.21e-1)" "unprognostic (3.34e-2)" "unprognostic (8.16e-3)" "unprognostic (1.81e-1)" "unprognostic (2.85e-2)" "unprognostic (2.78e-1)" "unprognostic (4.70e-1)" "unprognostic (1.25e-3)" "unprognostic (5.63e-2)" "unprognostic (4.35e-1)" AMBRA1 "DCAF3, FLJ20294, KIAA1736, WDR94" ENSG00000110497 "Autophagy and beclin 1 regulator 1" Q9C0C7 11 46396414-46594125 "Predicted intracellular proteins" "Autophagy, Cell cycle, Differentiation, Neurogenesis, Transcription, Transcription regulation, Ubl conjugation pathway" "Developmental protein" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 11.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017825, HPA038535" Approved Approved Vesicles,Mitochondria NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 49: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 61 Vesicles Mitochondria "CAB017825: , HPA038535: " "unprognostic (5.00e-2)" "unprognostic (4.81e-2)" "unprognostic (8.43e-2)" "potential prognostic unfavorable (9.29e-4)" "unprognostic (1.42e-1)" "unprognostic (6.40e-2)" "unprognostic (8.88e-2)" "unprognostic (1.78e-3)" "unprognostic (1.41e-1)" "unprognostic (6.74e-2)" "potential prognostic favorable (1.95e-4)" "unprognostic (8.86e-2)" "unprognostic (9.51e-2)" "potential prognostic unfavorable (8.58e-5)" "unprognostic (3.79e-2)" "unprognostic (4.29e-2)" "potential prognostic unfavorable (3.32e-4)" "unprognostic (2.80e-1)" "unprognostic (6.17e-2)" "unprognostic (3.47e-2)" "unprognostic (7.57e-2)" "unprognostic (6.03e-2)" "unprognostic (2.83e-2)" "unprognostic (1.61e-1)" "unprognostic (1.14e-2)" "unprognostic (1.16e-1)" "unprognostic (1.67e-1)" "unprognostic (3.45e-1)" "unprognostic (1.69e-1)" "unprognostic (9.93e-2)" "unprognostic (2.59e-1)" AMD1 SAMDC ENSG00000123505 "Adenosylmethionine decarboxylase 1" P17707 6 110874770-110898879 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Polyamine biosynthesis, Spermidine biosynthesis" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "prostate: 190.4" "Cell type enhanced" "Detected in many" "Megakaryocyte-Erythroid progenitors: 546.6;Platelets: 628.5;Prostatic glandular cells: 1120.8" "Cell type enhanced" "Detected in all" "oligodendrocyte: 254.2" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 203.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "HPA029281, HPA029282" Approved Approved Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 20: Non-specific - Transcription regulation" 6 Nucleoplasm "HPA029281: , HPA029282: " "unprognostic (1.28e-2)" "unprognostic (1.22e-3)" "unprognostic (1.99e-1)" "unprognostic (1.47e-1)" "potential prognostic favorable (4.73e-4)" "unprognostic (3.83e-2)" "unprognostic (2.14e-1)" "unprognostic (2.56e-2)" "unprognostic (1.51e-1)" "unprognostic (8.30e-2)" "validated prognostic favorable (1.80e-11)" "validated prognostic favorable (9.66e-4)" "unprognostic (4.54e-2)" "validated prognostic unfavorable (7.98e-7)" "validated prognostic unfavorable (6.40e-5)" "unprognostic (1.60e-1)" "unprognostic (2.53e-2)" "unprognostic (5.72e-2)" "unprognostic (9.50e-3)" "unprognostic (1.24e-1)" "unprognostic (1.14e-1)" "unprognostic (2.89e-1)" "unprognostic (5.42e-2)" "unprognostic (2.71e-1)" "unprognostic (3.39e-2)" "unprognostic (1.86e-1)" "unprognostic (2.80e-2)" "unprognostic (2.52e-1)" "unprognostic (3.10e-1)" "unprognostic (5.37e-2)" "unprognostic (1.86e-1)" AMDHD1 MGC35366 ENSG00000139344 "Amidohydrolase domain containing 1" Q96NU7 12 95943331-95968720 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Histidine metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 58.4;skeletal muscle: 25.4" "Group enriched" "Detected in many" 13 "Adrenal cortex cells: 85.4;Hepatocytes: 186.3" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Head and Neck Squamous Cell Carcinoma (TCGA): 185.6;Testicular Germ Cell Tumor (TCGA): 319.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Esophageal cancer: 59.8;head and neck cancer: 65.1" "Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA039720, HPA040149" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" No NA 1800000 "Cluster 45: Eosinophils - Unknown function" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 6: Non-specific - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 3 Cytosol "Nucleoplasm, Plasma membrane" "HPA039720: , HPA040149: " "unprognostic (8.45e-2)" "unprognostic (9.44e-2)" "unprognostic (2.03e-1)" "unprognostic (1.62e-1)" "potential prognostic unfavorable (2.30e-4)" "unprognostic (2.13e-1)" "unprognostic (2.04e-1)" "unprognostic (3.00e-2)" "unprognostic (2.21e-1)" "unprognostic (8.33e-3)" "unprognostic (9.77e-2)" "unprognostic (1.49e-3)" "unprognostic (1.27e-1)" "unprognostic (7.93e-2)" "unprognostic (3.63e-3)" "unprognostic (4.19e-2)" "unprognostic (2.66e-1)" "unprognostic (2.70e-2)" "unprognostic (4.99e-2)" "unprognostic (6.26e-2)" "unprognostic (9.47e-2)" "potential prognostic favorable (8.03e-4)" "unprognostic (2.70e-3)" "unprognostic (4.03e-2)" "unprognostic (2.82e-3)" "potential prognostic favorable (1.11e-4)" "unprognostic (3.55e-1)" "unprognostic (4.07e-2)" "unprognostic (1.69e-1)" "potential prognostic unfavorable (5.48e-4)" "unprognostic (2.70e-1)" AMDHD2 CGI-14 ENSG00000162066 "Amidohydrolase domain containing 2" Q9Y303 16 2520357-2531422 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 52.0;Enterocytes: 54.9;Hofbauer cells: 223.4;Kupffer cells: 69.7;Late primary spermatocytes: 129.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Lung - Macrophages, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041184, HPA041321" Enhanced Approved Nucleoli,Cytosol No No 65000 "Cluster 29: Non-specific - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 5 "Nucleoli, Cytosol" "HPA041184: , HPA041321: " "unprognostic (1.73e-1)" "unprognostic (1.73e-2)" "unprognostic (1.55e-1)" "unprognostic (5.44e-3)" "unprognostic (2.06e-3)" "unprognostic (5.70e-2)" "unprognostic (1.78e-2)" "unprognostic (1.78e-1)" "unprognostic (4.96e-2)" "unprognostic (1.91e-1)" "unprognostic (1.24e-3)" "unprognostic (2.80e-1)" "unprognostic (3.83e-3)" "unprognostic (2.91e-3)" "unprognostic (5.61e-2)" "unprognostic (1.06e-1)" "unprognostic (2.24e-1)" "unprognostic (1.18e-1)" "unprognostic (5.83e-2)" "unprognostic (1.26e-1)" "unprognostic (2.71e-1)" "unprognostic (3.99e-3)" "unprognostic (7.06e-3)" "unprognostic (2.13e-1)" "unprognostic (6.88e-2)" "unprognostic (6.64e-2)" "unprognostic (1.19e-1)" "unprognostic (3.04e-2)" "unprognostic (9.90e-3)" "unprognostic (4.04e-2)" "unprognostic (1.59e-1)" AMELX "AIH1, AMG" ENSG00000125363 "Amelogenin X-linked" Q99217 X 11293413-11300761 "Disease related genes, Human disease related genes, Predicted secreted proteins" Biomineralization "Amelogenesis imperfecta, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 11 "Epicardial cells: 45.5" "Cell type enhanced" "Detected in single" "pericyte: 1.1" "Group enriched" "Detected in some" 6 "Bladder Urothelial Carcinoma (TCGA): 7.3;Uterine Corpus Endometrial Carcinoma (TCGA): 3.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" Other NA NA "Cluster 44: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" AMELY AMGL ENSG00000099721 "Amelogenin Y-linked" Q99218 Y 6865918-6911752 "Predicted secreted proteins" Biomineralization "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 2.3;Ependymal cells: 1.1;Gastric chief cells: 1.1;Parietal cells: 1.8;Undifferentiated spermatogonia: 1.7" "Group enriched" "Detected in some" 4 "ependymal cell: 1.4;pericyte: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted in other tissues" Other NA NA "Cluster 63: Cytotrophoblasts - Basic cellular functions" AMER1 "FAM123B, FLJ39827, RP11-403E24.2, WTX" ENSG00000184675 "APC membrane recruitment protein 1" Q5JTC6 X 64185117-64205708 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Wnt signaling pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 14.3" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 10.6;Epididymal efferent duct absorptive cells: 8.5;Thymic myoid cells: 10.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065214, HPA065265" Approved Supported "Nuclear bodies,Vesicles,Plasma membrane" NA NA "Cluster 63: Non-specific - Basic cellular processes" "Cluster 1: Neurons - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 62: Smooth muscle cells - Muscle contraction" 19 "Nuclear bodies" "Vesicles, Plasma membrane" "HPA065214: , HPA065265: " "unprognostic (1.03e-1)" "unprognostic (3.02e-2)" "unprognostic (2.42e-1)" "unprognostic (5.44e-2)" "unprognostic (1.76e-1)" "unprognostic (1.98e-2)" "potential prognostic favorable (3.75e-6)" "unprognostic (4.65e-2)" "unprognostic (2.11e-1)" "potential prognostic favorable (2.77e-4)" "unprognostic (2.52e-2)" "unprognostic (2.32e-2)" "unprognostic (5.06e-2)" "unprognostic (2.55e-1)" "unprognostic (4.04e-2)" "unprognostic (3.57e-2)" "potential prognostic favorable (2.64e-4)" "unprognostic (1.42e-1)" "unprognostic (1.99e-1)" "unprognostic (1.05e-1)" "unprognostic (1.19e-1)" "unprognostic (1.12e-1)" "potential prognostic favorable (1.14e-5)" "unprognostic (2.14e-2)" "unprognostic (1.24e-1)" "unprognostic (3.43e-1)" "unprognostic (2.77e-1)" "unprognostic (1.43e-1)" "unprognostic (4.51e-2)" AMER2 "FAM123A, FLJ25477" ENSG00000165566 "APC membrane recruitment protein 2" Q8N7J2 13 25161679-25172288 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 35.0;retina: 23.9" "Group enriched" "Detected in some" 4 "Astrocytes: 131.8;Bergmann glia: 344.0;Müller glia: 278.9;Oligodendrocytes: 358.9;Retinal horizontal cells: 106.2" "Group enriched" "Detected in all" 4 "astrocyte: 131.4;Bergmann glia: 341.1;committed oligodendrocyte precursor: 119.8;oligodendrocyte: 405.3" "Cancer enriched" "Detected in single" 20 "Glioblastoma Multiforme (TCGA): 8.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Bone cancer: 21.5" "Adrenal gland - Adrenal medulla cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039458 Enhanced Supported "Plasma membrane" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 11: Muller glia cells - Retinal homeostasis" 1 "Plasma membrane" "HPA039458: " "unprognostic (1.40e-1)" "unprognostic (2.07e-2)" AMER3 "FAM123C, FLJ38377" ENSG00000178171 "APC membrane recruitment protein 3" Q8N944 2 130755540-130768134 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 8.1" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 10.6;Brain excitatory neurons: 14.2;Brain inhibitory neurons: 9.3;Cone photoreceptor cells: 6.2;Corticotrophs: 5.5;Gonadotrophs: 5.8;Lactotrophs: 4.8;Neuroendocrine cells: 15.2;Other brain neurons: 10.8;Pancreatic islet cells: 11.0;Retinal bipolar cells: 7.8;Retinal horizontal cells: 6.0;Rod photoreceptor cells: 4.8;Thyrotrophs: 6.4;Undifferentiated spermatogonia: 4.0" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 4.5;prostate cancer: 1.8" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Stomach - Gastric enteroendocrine cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045593, HPA054230" Uncertain Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 37: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" 3 "Nuclear bodies" "Nucleoplasm, Cytosol" "HPA045593: , HPA054230: " "unprognostic (6.15e-3)" AMFR "gp78, RNF45" ENSG00000159461 "Autocrine motility factor receptor" Q9UKV5 16 56361452-56425545 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ubl conjugation pathway, Wnt signaling pathway" "Receptor, Transferase" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 235.7;Hepatocytes: 202.5;Platelets: 361.0;Renal collecting duct intercalated cells: 237.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026381, HPA029018, HPA064339, HPA077835" Approved Supported "Endoplasmic reticulum,Golgi apparatus" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 47: Platelets - Hemostasis" 105 "Endoplasmic reticulum, Golgi apparatus" "CAB026381: , HPA029018: , HPA064339: , HPA077835: " "unprognostic (1.63e-1)" "unprognostic (1.03e-1)" "unprognostic (2.08e-1)" "unprognostic (2.01e-2)" "unprognostic (1.41e-1)" "unprognostic (5.92e-2)" "unprognostic (3.63e-1)" "unprognostic (5.66e-1)" "unprognostic (1.81e-2)" "unprognostic (2.57e-1)" "unprognostic (2.22e-3)" "unprognostic (3.33e-2)" "unprognostic (3.41e-1)" "unprognostic (9.93e-2)" "unprognostic (1.42e-2)" "unprognostic (4.13e-3)" "unprognostic (1.07e-2)" "unprognostic (3.34e-2)" "unprognostic (1.07e-2)" "unprognostic (1.34e-1)" "unprognostic (8.86e-2)" "unprognostic (2.09e-1)" "unprognostic (7.02e-2)" "unprognostic (8.57e-2)" "unprognostic (5.99e-2)" "unprognostic (2.12e-1)" "unprognostic (2.96e-1)" "unprognostic (2.51e-1)" "unprognostic (4.19e-1)" "unprognostic (1.87e-1)" "unprognostic (1.49e-1)" AMH "MIF, MIS" ENSG00000104899 "Anti-Mullerian hormone" P03971 19 2249309-2252073 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Differentiation, Gonadal differentiation" "Growth factor" "Disease variant, Pseudohermaphroditism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 5.3;pituitary gland: 3.8;testis: 10.0" "Cell type enriched" "Detected in some" 12 "Granulosa cells: 799.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA066973 Approved Vesicles,Aggresome "Secreted to blood" "Growth factor" NA NA 1580000 710000 "Cluster 67: Testis - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 23: Non-specific - Transcription" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 1 "Vesicles, Aggresome" "HPA066973: " "unprognostic (6.91e-2)" "unprognostic (1.09e-2)" "unprognostic (1.45e-3)" "unprognostic (2.98e-1)" "potential prognostic favorable (2.78e-4)" "unprognostic (2.79e-1)" "unprognostic (1.36e-1)" "unprognostic (4.08e-2)" "unprognostic (1.10e-1)" "unprognostic (3.17e-2)" "unprognostic (3.33e-2)" "unprognostic (3.97e-2)" "unprognostic (4.88e-1)" AMHR2 "MISR2, MISRII" ENSG00000135409 "Anti-Mullerian hormone receptor type 2" Q16671 12 53423855-53431672 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease variant, Pseudohermaphroditism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 38.9;ovary: 32.4" "Cell type enhanced" "Detected in some" "Adrenal cortex cells: 52.5;Granulosa cells: 142.7;Mast cells: 20.5;Megakaryocyte-Erythroid progenitors: 9.7;Ovarian stromal cells: 26.9;Sertoli cells: 25.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 3.2" "Region enhanced" "Detected in single" "hypothalamus: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Leukemia: 5.0;liver cancer: 4.7" "Adipose subcutaneous - Mast cells, Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal cortex cells, Colon - Mast cells, Liver - Sinusoid Endothelial cells, Pancreas - Exocrine glandular cells, Skin - Mast cells, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Region enriched" "Detected in some" 10 "hippocampal formation: 13.5" "HPA060228, HPA069636" Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 47: Leukemia - Hemostasis" "Cluster 18: Adrenal cortex cells - Steroidogensis" 21 Vesicles "Nucleoplasm, Cytosol" "HPA060228: , HPA069636: " "unprognostic (4.03e-2)" "unprognostic (3.07e-1)" AMIGO1 "AMIGO, KIAA1163" ENSG00000181754 "Adhesion molecule with Ig like domain 1" Q86WK6 1 109504178-109509738 "Predicted membrane proteins, Transporters" "Cell adhesion, Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 9.8;Brain inhibitory neurons: 14.0;Oocytes: 13.8;Other brain neurons: 12.4;Retinal amacrine cells: 16.3;Retinal bipolar cells: 22.2;Retinal pigment epithelial cells: 12.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 2.3" "Lineage enhanced" "Detected in single" "T-cells: 2.3" "Low cancer specificity" "Detected in many" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046152, HPA062080" Approved Approved Vesicles NA NA "Cluster 27: T-cells - Unknown function" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 34 Vesicles "HPA046152: , HPA062080: " "unprognostic (6.66e-2)" "unprognostic (2.37e-1)" "unprognostic (3.44e-1)" "unprognostic (3.86e-2)" "potential prognostic favorable (4.97e-4)" "unprognostic (2.23e-1)" "unprognostic (1.34e-1)" "unprognostic (3.87e-2)" "unprognostic (3.85e-2)" "unprognostic (3.50e-2)" "potential prognostic favorable (3.73e-7)" "unprognostic (5.30e-2)" "unprognostic (2.27e-3)" "potential prognostic unfavorable (2.83e-5)" "unprognostic (1.74e-2)" "unprognostic (3.71e-3)" "unprognostic (4.69e-2)" "unprognostic (1.26e-1)" "unprognostic (9.63e-3)" "unprognostic (6.19e-2)" "unprognostic (8.17e-3)" "unprognostic (6.68e-3)" "potential prognostic favorable (5.40e-4)" "unprognostic (1.81e-1)" "unprognostic (1.66e-1)" "unprognostic (5.17e-2)" "unprognostic (5.75e-2)" "unprognostic (4.84e-2)" "unprognostic (1.43e-1)" "unprognostic (3.41e-1)" "unprognostic (3.42e-2)" AMIGO2 "ALI1, DEGA" ENSG00000139211 "Adhesion molecule with Ig like domain 2" Q86SJ2 12 47075707-47079959 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 68.2" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 108.5;Endometrial glandular cells: 86.2;Endometrial luminal cells: 46.3;Epididymal basal cells: 92.4;Epididymal efferent duct absorptive cells: 48.7;Epididymal efferent duct ciliated cells: 59.2;Fallopian tube ciliated cells: 45.7;Platelets: 96.1;Smooth muscle cells: 60.2;Urothelial cells: 73.6;Vascular smooth muscle cells: 57.1" "Cell type enhanced" "Detected in many" "midbrain-derived inhibitory: 19.4;vascular associated smooth muscle cell: 25.2" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "midbrain: 75.4" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Kidney cancer: 207.1" "Adipose subcutaneous - Smooth muscle cells, Breast - Breast myoepithelial cells, Prostate - Smooth muscle cells, Skeletal muscle - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054004, HPA059601" Uncertain Approved "Golgi apparatus,Plasma membrane,Cytosol" NA Yes 240000 "Cluster 11: T-cells - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 98: Neurons - Neurotransmission & signaling" 4 "Golgi apparatus, Plasma membrane" Cytosol "HPA054004: , HPA059601: " "unprognostic (3.32e-1)" "unprognostic (2.71e-1)" "unprognostic (3.47e-2)" "unprognostic (1.85e-3)" "unprognostic (8.29e-3)" "unprognostic (8.40e-2)" "unprognostic (4.28e-1)" "unprognostic (3.81e-2)" "unprognostic (7.27e-3)" "unprognostic (1.47e-2)" "unprognostic (3.56e-2)" "unprognostic (2.40e-1)" "unprognostic (5.87e-3)" "unprognostic (8.87e-2)" "unprognostic (6.04e-3)" "unprognostic (5.93e-2)" "unprognostic (4.12e-2)" "unprognostic (5.34e-3)" "unprognostic (1.90e-3)" "unprognostic (9.19e-2)" "unprognostic (3.85e-1)" "potential prognostic unfavorable (7.72e-5)" "unprognostic (3.64e-2)" "unprognostic (3.66e-2)" "unprognostic (2.35e-1)" "unprognostic (1.77e-1)" "unprognostic (2.84e-1)" "unprognostic (2.92e-3)" "unprognostic (3.80e-1)" "unprognostic (5.80e-2)" "unprognostic (1.68e-3)" AMIGO3 ENSG00000176020 "Adhesion molecule with Ig like domain 3" Q86WK7 3 49716829-49719684 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Epididymal principal cells: 1.2;Goblet cells: 1.6;Neuroendocrine cells: 1.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 10 "plasmacytoid DC: 11.0" "Lineage enriched" "Detected in many" 10 "dendritic cells: 11.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA026673 Approved "Actin filaments" NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 24: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 70: Intestinal goblet cells - Mucin production" "Actin filaments" "HPA026673: " "unprognostic (4.90e-1)" "unprognostic (3.25e-1)" "unprognostic (3.45e-2)" "unprognostic (4.82e-2)" "unprognostic (3.15e-1)" "unprognostic (2.19e-1)" "unprognostic (1.27e-1)" "unprognostic (3.41e-3)" "potential prognostic unfavorable (8.14e-4)" "unprognostic (1.60e-1)" "unprognostic (1.87e-1)" "unprognostic (1.68e-1)" "unprognostic (6.29e-2)" "unprognostic (1.32e-1)" "unprognostic (4.19e-2)" "unprognostic (8.46e-2)" "unprognostic (9.80e-2)" "unprognostic (2.10e-1)" "unprognostic (1.54e-1)" "unprognostic (6.06e-2)" "unprognostic (1.47e-1)" AMMECR1 ENSG00000101935 "AMMECR nuclear protein 1" Q9Y4X0 X 110194186-110440318 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Alport syndrome, Deafness, Disease variant, Elliptocytosis, Hereditary hemolytic anemia, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Cardiomyocytes: 1501.6;Choroid plexus epithelial cells: 1339.2" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 1003.4" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "choroid plexus: 16.9" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA000590, HPA051762" Uncertain Supported Nucleoplasm,Mitochondria NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 9 Nucleoplasm Mitochondria "HPA000590: , HPA051762: " "unprognostic (1.68e-1)" "unprognostic (6.77e-2)" "unprognostic (4.11e-1)" "unprognostic (2.75e-1)" "unprognostic (1.39e-1)" "unprognostic (7.74e-2)" "unprognostic (5.33e-2)" "unprognostic (5.06e-2)" "unprognostic (3.64e-2)" "unprognostic (5.83e-3)" "unprognostic (8.69e-2)" "unprognostic (1.82e-3)" "potential prognostic unfavorable (1.68e-4)" "potential prognostic unfavorable (5.01e-4)" "unprognostic (3.13e-3)" "unprognostic (6.11e-2)" "unprognostic (5.11e-2)" "unprognostic (8.74e-2)" "unprognostic (2.90e-1)" "unprognostic (4.10e-3)" "unprognostic (1.97e-1)" "unprognostic (2.01e-2)" "unprognostic (1.47e-1)" "unprognostic (3.39e-2)" "unprognostic (7.87e-2)" "unprognostic (2.27e-1)" "unprognostic (5.62e-2)" "unprognostic (2.75e-1)" "unprognostic (4.51e-2)" "unprognostic (1.06e-2)" "unprognostic (1.76e-2)" AMMECR1L MGC4268 ENSG00000144233 "AMMECR1 like" Q6DCA0 2 127861630-127885967 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000590, HPA057234" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 57: Testis - Spermatogenesis" "Cluster 53: Neurons - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 108: Fibroblasts - ECM organization" 2 Nucleoplasm Cytosol "HPA000590: , HPA057234: " "unprognostic (1.40e-2)" "unprognostic (1.50e-2)" "unprognostic (3.60e-1)" "unprognostic (5.92e-2)" "unprognostic (4.54e-2)" "unprognostic (6.69e-2)" "unprognostic (3.25e-1)" "unprognostic (8.05e-3)" "unprognostic (2.52e-1)" "unprognostic (3.14e-1)" "validated prognostic favorable (4.10e-7)" "validated prognostic favorable (3.67e-4)" "unprognostic (3.26e-1)" "unprognostic (5.99e-2)" "unprognostic (2.28e-1)" "unprognostic (9.06e-2)" "unprognostic (3.17e-2)" "unprognostic (4.11e-2)" "unprognostic (3.82e-2)" "unprognostic (1.50e-1)" "unprognostic (1.07e-1)" "unprognostic (7.36e-2)" "unprognostic (2.58e-2)" "unprognostic (1.99e-2)" "unprognostic (2.30e-1)" "unprognostic (4.12e-2)" "unprognostic (3.75e-1)" "unprognostic (1.33e-1)" "unprognostic (3.00e-1)" "unprognostic (6.56e-2)" "unprognostic (2.24e-1)" AMN amnionless ENSG00000166126 "Amnion associated transmembrane protein" Q9BXJ7 14 102922663-102933596 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Protein transport, Transport" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "intestine: 86.9;kidney: 52.4;liver: 55.2" "Cell type enhanced" "Detected in many" "Colonocytes: 601.8;Enteric transient amplifying cells: 237.6;Enterocytes: 1882.7;Epididymal efferent duct absorptive cells: 400.2;Goblet cells: 297.3" "Cell type enhanced" "Detected in some" "hippocampal CA1-3: 4.9;hippocampal CA4: 5.7" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 89.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 7.1;Gastric cancer: 6.2;liver cancer: 6.1" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Minor Salivary Gland - Minor salivary gland basal cells, Pancreas - Ductal cells, Prostate - Urothelial cells, Spleen - B-cells (Spleen), Stomach - Gastric mucous cells" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA000817 Approved "Secreted in other tissues" Transport NA NA "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 1 "HPA000817: " "unprognostic (5.01e-2)" "unprognostic (5.77e-2)" "unprognostic (7.65e-3)" "unprognostic (1.08e-2)" "unprognostic (1.40e-2)" "unprognostic (4.82e-3)" "potential prognostic favorable (3.82e-9)" "unprognostic (9.80e-3)" "potential prognostic favorable (8.74e-4)" "unprognostic (1.74e-1)" "unprognostic (1.53e-1)" "unprognostic (1.87e-2)" "unprognostic (1.70e-1)" "unprognostic (2.69e-1)" "unprognostic (9.66e-2)" "unprognostic (1.75e-1)" "unprognostic (1.02e-2)" "unprognostic (8.01e-2)" "unprognostic (7.79e-2)" "unprognostic (3.34e-1)" "unprognostic (2.69e-1)" "unprognostic (3.35e-2)" AMN1 ENSG00000151743 "Antagonist of mitotic exit network 1 homolog" Q8IY45 12 31671142-31729121 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 52.9" "Cell type enhanced" "Detected in all" "Early spermatids: 563.2;Late primary spermatocytes: 571.9;Late spermatids: 188.5;Neutrophils: 361.7;Rod photoreceptor cells: 218.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 52.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046157, HPA062290" Approved Approved Centrosome NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 1 Centrosome "HPA046157: , HPA062290: " "unprognostic (5.88e-2)" "unprognostic (1.12e-1)" "unprognostic (9.47e-2)" "unprognostic (4.70e-2)" "unprognostic (2.74e-1)" "unprognostic (2.28e-1)" "unprognostic (4.02e-1)" "unprognostic (1.49e-1)" "unprognostic (6.06e-2)" "potential prognostic unfavorable (5.47e-4)" "unprognostic (2.06e-3)" "unprognostic (1.70e-2)" "unprognostic (6.88e-2)" "unprognostic (2.54e-3)" "unprognostic (2.27e-1)" "unprognostic (1.47e-2)" "unprognostic (2.28e-2)" "unprognostic (7.61e-2)" "unprognostic (7.21e-2)" "unprognostic (1.08e-1)" "unprognostic (9.84e-2)" "unprognostic (2.59e-1)" "unprognostic (7.14e-3)" "unprognostic (4.17e-2)" "unprognostic (3.65e-3)" "unprognostic (2.38e-1)" "unprognostic (3.72e-2)" "unprognostic (3.26e-2)" "unprognostic (1.01e-1)" "unprognostic (1.57e-1)" "unprognostic (7.84e-2)" AMOT KIAA1071 ENSG00000126016 Angiomotin Q4VCS5 X 112774503-112840831 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 137.7;tongue: 51.2" "Cell type enhanced" "Detected in many" "Astrocytes: 93.6;Cytotrophoblasts: 83.2;Epididymal principal cells: 323.7;Myonuclei: 83.7;Pituitary stem cells: 403.0;Prostatic glandular cells: 67.1" "Cell type enhanced" "Detected in many" "astrocyte: 101.7;central nervous system macrophage: 55.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 33.5" "Skeletal muscle - Skeletal myocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067290, HPA067853" Enhanced Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" 81 "Cell Junctions" Nucleoplasm "HPA067290: , HPA067853: " "unprognostic (1.44e-2)" "unprognostic (1.57e-2)" "unprognostic (1.23e-1)" "unprognostic (4.66e-2)" "unprognostic (1.07e-1)" "unprognostic (4.60e-1)" "unprognostic (2.66e-1)" "unprognostic (1.08e-1)" "unprognostic (6.24e-2)" "unprognostic (6.21e-3)" "potential prognostic favorable (4.58e-11)" "unprognostic (5.33e-3)" "unprognostic (9.82e-3)" "unprognostic (5.04e-2)" "unprognostic (6.29e-2)" "unprognostic (4.82e-3)" "unprognostic (7.91e-2)" "unprognostic (2.05e-2)" "unprognostic (4.27e-3)" "unprognostic (1.37e-1)" "potential prognostic unfavorable (1.38e-4)" "unprognostic (3.80e-1)" "potential prognostic favorable (8.11e-4)" "unprognostic (1.11e-1)" "unprognostic (6.17e-2)" "unprognostic (8.26e-2)" "unprognostic (7.18e-2)" "unprognostic (2.41e-1)" "unprognostic (1.79e-1)" "unprognostic (1.30e-1)" "unprognostic (7.30e-3)" AMOTL1 JEAP ENSG00000166025 "Angiomotin like 1" Q8IY63 11 94706431-94876748 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 104.6" "Cell type enhanced" "Detected in many" "Medullary thymic epithelial cells: 225.6;Myonuclei: 391.0;Thymic myoid cells: 830.7" "Cell type enhanced" "Detected in all" "fibroblast: 227.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Lung - Endothelial cells, Spleen - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001196 Approved Approved "Cell Junctions,Cytosol" NA NA 9400 "Cluster 63: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 25 Cytosol "Cell Junctions" "HPA001196: " "unprognostic (3.12e-1)" "unprognostic (3.05e-1)" "unprognostic (9.10e-3)" "unprognostic (3.00e-3)" "unprognostic (1.76e-2)" "unprognostic (9.98e-2)" "unprognostic (6.51e-2)" "potential prognostic favorable (5.39e-4)" "unprognostic (1.72e-2)" "unprognostic (3.61e-2)" "validated prognostic favorable (1.34e-7)" "validated prognostic favorable (2.52e-4)" "unprognostic (6.70e-2)" "unprognostic (1.13e-1)" "unprognostic (6.54e-3)" "unprognostic (1.27e-1)" "unprognostic (1.10e-1)" "unprognostic (2.89e-1)" "unprognostic (1.69e-1)" "unprognostic (1.26e-1)" "unprognostic (1.47e-2)" "unprognostic (1.77e-1)" "unprognostic (2.07e-1)" "unprognostic (7.57e-2)" "unprognostic (1.46e-2)" "unprognostic (9.05e-2)" "unprognostic (4.91e-2)" "unprognostic (9.90e-3)" "unprognostic (1.30e-1)" "unprognostic (3.69e-2)" "unprognostic (7.73e-2)" AMOTL2 LCCP ENSG00000114019 "Angiomotin like 2" Q9Y2J4 3 134355347-134375479 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 54.0;Cardiomyocytes: 22.7;Distal convoluted tubule cells: 20.0;Endometrial secretory cells: 23.7;Loop of henle epithelial cells: 25.5;Mesothelial cells: 19.8;Podocytes: 85.9;Proximal tubule cells: 29.7;Renal collecting duct intercalated cells: 21.2" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 15.8;oligodendrocyte: 13.4;pericyte: 12.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063027 Approved "Cell Junctions" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 57: Podocytes - Glomerular filtration" 61 "Cell Junctions" "HPA063027: " "unprognostic (1.01e-1)" "unprognostic (4.61e-2)" "unprognostic (3.85e-1)" "unprognostic (2.20e-2)" "unprognostic (1.28e-1)" "unprognostic (9.05e-2)" "unprognostic (4.24e-2)" "potential prognostic favorable (1.75e-5)" "unprognostic (5.59e-2)" "unprognostic (1.08e-1)" "unprognostic (2.94e-3)" "unprognostic (1.03e-1)" "unprognostic (5.71e-2)" "unprognostic (3.74e-1)" "unprognostic (6.42e-2)" "unprognostic (2.37e-1)" "unprognostic (3.45e-1)" "unprognostic (5.54e-2)" "unprognostic (2.70e-1)" "unprognostic (2.02e-2)" "unprognostic (2.90e-2)" "unprognostic (1.79e-2)" "unprognostic (1.06e-2)" "unprognostic (1.92e-1)" "unprognostic (6.08e-2)" "potential prognostic favorable (9.94e-4)" "unprognostic (4.76e-2)" "unprognostic (2.03e-1)" "unprognostic (1.40e-1)" "unprognostic (1.67e-1)" "unprognostic (3.34e-3)" AMPD1 "MAD, MADA" ENSG00000116748 "Adenosine monophosphate deaminase 1" P23109 1 114673090-114695618 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 24 "skeletal muscle: 538.0;tongue: 202.3" "Cell type enriched" "Detected in some" 11 "Myonuclei: 908.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Head and Neck Squamous Cell Carcinoma (TCGA): 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 29 "Myeloma: 58.4" "Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Skeletal myocytes, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA026478, HPA028080" Enhanced NA NA 12000 "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" "HPA026478: , HPA028080: " "unprognostic (1.43e-1)" "unprognostic (2.31e-1)" "unprognostic (6.16e-2)" "unprognostic (7.12e-3)" "unprognostic (2.14e-2)" "unprognostic (2.93e-1)" AMPD2 SPG63 ENSG00000116337 "Adenosine monophosphate deaminase 2" Q01433 1 109616104-109632051 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 68.9" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 95.7;monocytes: 63.4;Neutrophils: 79.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 19.4;eosinophil: 19.3;intermediate monocyte: 40.7;myeloid DC: 18.9;neutrophil: 61.2;non-classical monocyte: 44.8" "Group enriched" "Detected in all" 5 "dendritic cells: 18.9;granulocytes: 61.2;monocytes: 44.8" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027137, HPA045760" Approved Approved Cytosol NA NA 160000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 8 Cytosol "HPA027137: , HPA045760: " "unprognostic (2.88e-2)" "unprognostic (1.59e-2)" "unprognostic (4.52e-2)" "unprognostic (2.03e-1)" "unprognostic (4.83e-3)" "unprognostic (1.16e-2)" "unprognostic (1.21e-1)" "unprognostic (2.65e-3)" "unprognostic (3.98e-3)" "unprognostic (3.83e-2)" "unprognostic (8.77e-2)" "unprognostic (3.36e-2)" "unprognostic (1.97e-1)" "unprognostic (7.72e-3)" "unprognostic (2.61e-1)" "unprognostic (4.96e-2)" "unprognostic (1.50e-2)" "unprognostic (1.97e-1)" "unprognostic (6.10e-2)" "unprognostic (6.38e-2)" "unprognostic (1.13e-1)" "unprognostic (1.19e-1)" "unprognostic (9.13e-2)" "unprognostic (1.24e-1)" "unprognostic (3.81e-1)" "unprognostic (5.90e-2)" "unprognostic (3.91e-1)" "unprognostic (8.00e-2)" "unprognostic (1.04e-1)" "unprognostic (1.17e-2)" "unprognostic (1.70e-1)" AMPD3 ENSG00000133805 "Adenosine monophosphate deaminase 3" Q01432 11 10308313-10507579 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 56.8;skeletal muscle: 61.1" "Cell type enhanced" "Detected in many" "Epididymal clear cells: 181.7;Gonadotrophs: 203.2;Neutrophil progenitors: 228.6;Neutrophils: 186.9;Ocular epithelial cells: 149.4;Thymic myoid cells: 161.8;Thyrotrophs: 151.1" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 119.2;committed oligodendrocyte precursor: 95.8;oligodendrocyte: 129.5" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 38.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adrenal gland - Adrenal cortex cells, Pituitary gland - Gonadotropes, Skin - Keratinocyte (other), Spleen - B-cells (Spleen), Stomach - Gastric mucous cells, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038662, HPA047408" Uncertain Approved "Nuclear membrane,Nucleoli" NA NA 51000 "Cluster 21: Neutrophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 2 "Nuclear membrane" Nucleoli "HPA038662: , HPA047408: " "unprognostic (1.83e-1)" "unprognostic (6.73e-2)" "unprognostic (1.13e-2)" "unprognostic (9.78e-2)" "unprognostic (8.33e-3)" "unprognostic (2.33e-1)" "unprognostic (1.32e-2)" "unprognostic (1.93e-1)" "unprognostic (1.11e-3)" "potential prognostic unfavorable (7.98e-4)" "unprognostic (1.78e-1)" "unprognostic (1.39e-1)" "unprognostic (1.06e-1)" "unprognostic (3.73e-3)" "unprognostic (1.83e-1)" "unprognostic (1.27e-1)" "unprognostic (4.50e-2)" "unprognostic (2.80e-2)" "unprognostic (2.82e-3)" "unprognostic (1.38e-1)" "unprognostic (8.13e-2)" "unprognostic (3.97e-2)" "unprognostic (1.77e-2)" "unprognostic (3.76e-1)" "unprognostic (1.29e-1)" "unprognostic (7.71e-3)" "unprognostic (2.25e-2)" "unprognostic (1.65e-1)" "unprognostic (2.42e-2)" "unprognostic (2.47e-1)" "unprognostic (5.97e-2)" AMPH ENSG00000078053 Amphiphysin P49418 7 38383704-38631420 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 51.0;pituitary gland: 20.1;retina: 61.1" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 262.9;Brain inhibitory neurons: 198.5;Cone photoreceptor cells: 438.9;Corticotrophs: 187.2;Fibro-adipogenic progenitors: 143.2;Gonadotrophs: 165.7;Lactotrophs: 256.2;monocytes: 195.1;Neutrophils: 134.9;Oligodendrocyte progenitor cells: 136.2;Other brain neurons: 201.9;Retinal amacrine cells: 288.5;Retinal bipolar cells: 294.0;Retinal ganglion cells: 177.7;Rod photoreceptor cells: 427.4;Somatotrophs: 268.2;Thyrotrophs: 300.6" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 10.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 16.7" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008559, HPA019828, HPA019829" Enhanced Supported "Plasma membrane,Cytosol" NA NA 450000 "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 72: Neuronal - Signal transduction" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 31 Cytosol "Plasma membrane" "CAB008559: , HPA019828: , HPA019829: " "unprognostic (1.33e-2)" "unprognostic (2.19e-1)" "unprognostic (6.21e-2)" "unprognostic (1.41e-2)" "potential prognostic favorable (4.77e-4)" "unprognostic (1.33e-1)" "unprognostic (1.22e-1)" "unprognostic (4.94e-2)" "unprognostic (6.64e-2)" "unprognostic (3.71e-2)" "unprognostic (2.01e-3)" "unprognostic (2.19e-3)" "unprognostic (1.15e-1)" "unprognostic (1.47e-1)" "unprognostic (4.41e-2)" "unprognostic (1.01e-2)" "unprognostic (7.96e-2)" AMT "GCST, NKH" ENSG00000145020 Aminomethyltransferase P48728 3 49416778-49422685 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Aminotransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 52.5" "Cell type enhanced" "Detected in some" "Astrocytes: 18.3;Bergmann glia: 15.8;Brain excitatory neurons: 11.6;Brain inhibitory neurons: 12.1;Choroid plexus epithelial cells: 10.7;Ependymal cells: 21.8;Microglia: 8.8;Oligodendrocyte progenitor cells: 12.2;Oligodendrocytes: 8.2;Other brain neurons: 4.7" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 22.7" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "NK-cell: 7.9" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "liver cancer: 9.7;testis cancer: 8.3" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005566 Supported Supported Nucleoplasm,Mitochondria NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 70: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 18: Liver cancer - Metabolism" "Cluster 22: Non-specific - Basic cellular functions" 1 Mitochondria Nucleoplasm "HPA005566: " "unprognostic (1.17e-1)" "unprognostic (1.69e-2)" "unprognostic (7.74e-3)" "unprognostic (5.62e-2)" "unprognostic (4.18e-3)" "unprognostic (2.13e-1)" "unprognostic (6.66e-2)" "unprognostic (5.24e-2)" "potential prognostic favorable (2.84e-8)" "unprognostic (6.89e-3)" "potential prognostic favorable (3.97e-7)" "unprognostic (8.13e-2)" "unprognostic (1.60e-3)" "potential prognostic favorable (9.19e-5)" "unprognostic (1.98e-1)" "unprognostic (1.63e-2)" "unprognostic (2.10e-1)" "unprognostic (2.24e-2)" "unprognostic (1.04e-2)" "unprognostic (1.01e-1)" "unprognostic (2.59e-1)" "potential prognostic favorable (2.59e-4)" "unprognostic (3.08e-3)" "unprognostic (1.81e-1)" "unprognostic (4.03e-1)" "unprognostic (1.70e-1)" "unprognostic (7.29e-2)" AMTN "RSTI689, UNQ689" ENSG00000187689 Amelotin Q6UX39 4 70518569-70532743 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Biomineralization, Cell adhesion" "Amelogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 26.5;salivary gland: 6.2;stomach 1: 6.9" "Cell type enhanced" "Detected in some" "Esophageal apical cells: 6.7;Foveolar cells: 22.5;Prostatic glandular cells: 3.8;Salivary acinar cells: 10.8;Salivary basal cells: 37.8;Salivary duct cells: 4.8;Salivary myoepithelial cells: 3.6" "Not detected" "Not detected" "Group enriched" "Detected in many" 18 "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 25.9;Head and Neck Squamous Cell Carcinoma (TCGA): 71.8;Lung Squamous Cell Carcinoma (TCGA): 48.9" "Region enhanced" "Detected in single" "white matter: 1.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 13.6;liver cancer: 11.1;Uterine cancer: 15.5" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA036136, HPA036137" Uncertain "Secreted in other tissues" "Cell adhesion" NA NA "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 21: Non-specific - Metabolism" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 68: Foveolar cells - Mucosal defense" 10 "HPA036136: , HPA036137: " "unprognostic (5.17e-1)" "unprognostic (2.38e-1)" "unprognostic (1.06e-1)" "unprognostic (1.20e-1)" "unprognostic (1.35e-1)" "unprognostic (1.19e-1)" "unprognostic (6.81e-2)" "unprognostic (4.34e-1)" "unprognostic (3.74e-1)" "unprognostic (9.14e-2)" AMY1A AMY1 ENSG00000237763 "Amylase alpha 1A" P0DUB6 1 103655760-103664554 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Carbohydrate metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 305 "salivary gland: 7769.4" "Group enriched" "Detected in some" 9 "Salivary acinar cells: 14.4;Salivary myoepithelial cells: 4.8" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Lung Adenocarcinoma (TCGA): 6.8;Ovary Serous Cystadenocarcinoma (TCGA): 21.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Exocrine glandular cells" "CAB004310, HPA045394, HPA045399, HPA046980" Enhanced Approved "Golgi apparatus,Cytosol" "Secreted to digestive system" Enzyme NA NA "Cluster 82: Salivary gland - Secretion" "Cluster 15: Kidney cancer - Membrane components" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 1 "Golgi apparatus, Cytosol" "CAB004310: , HPA045394: , HPA045399: , HPA046980: " "unprognostic (2.49e-2)" "unprognostic (2.19e-1)" "potential prognostic favorable (6.98e-5)" "unprognostic (1.59e-1)" "unprognostic (2.03e-1)" "unprognostic (3.61e-2)" "unprognostic (2.91e-2)" "unprognostic (7.52e-2)" "unprognostic (8.17e-2)" AMY1B AMY1 ENSG00000174876 "Amylase alpha 1B" P0DTE7 1 103687415-103696454 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Carbohydrate metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 97 "salivary gland: 9825.3" "Cell type enhanced" "Detected in some" "Pancreatic acinar cells: 1.7;Salivary acinar cells: 5.4;Salivary myoepithelial cells: 1.3" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 8 "Ovary Serous Cystadenocarcinoma (TCGA): 43.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Exocrine glandular cells" "HPA045394, HPA045399, HPA046980" Supported Approved "Golgi apparatus,Cytosol" "Secreted to digestive system" Enzyme NA NA 78000000 "Cluster 82: Salivary gland - Secretion" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 38: Secretory epithelial cells - Exocrine secretion" "Golgi apparatus, Cytosol" "HPA045394: , HPA045399: , HPA046980: " "unprognostic (2.08e-3)" "unprognostic (1.89e-1)" "unprognostic (5.09e-1)" "unprognostic (3.19e-2)" "unprognostic (1.47e-2)" "unprognostic (7.49e-2)" "unprognostic (4.81e-2)" AMY1C AMY1 ENSG00000187733 "Amylase alpha 1C" P0DTE8 1 103745323-103758726 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Carbohydrate metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 66 "salivary gland: 7880.0" "Cell type enhanced" "Detected in single" "Salivary acinar cells: 2.0" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 75.0;Ovary Serous Cystadenocarcinoma (TCGA): 31.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Exocrine glandular cells" "HPA045394, HPA045399, HPA046980" Supported Approved "Golgi apparatus,Cytosol" "Secreted to digestive system" Enzyme NA NA "Cluster 82: Salivary gland - Secretion" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 38: Secretory epithelial cells - Exocrine secretion" "Golgi apparatus, Cytosol" "HPA045394: , HPA045399: , HPA046980: " "unprognostic (2.77e-1)" "unprognostic (4.40e-1)" "unprognostic (2.40e-3)" "unprognostic (2.52e-2)" "unprognostic (4.49e-2)" "unprognostic (2.58e-2)" "unprognostic (1.12e-2)" "unprognostic (3.20e-1)" "unprognostic (1.90e-3)" "unprognostic (4.44e-3)" AMY2A AMY2 ENSG00000243480 "Amylase alpha 2A" P04746 1 103617427-103625780 "Enzymes, Essential proteins, FDA approved drug targets, Metabolic proteins, Predicted secreted proteins" "Carbohydrate metabolism" "Glycosidase, Hydrolase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4661 "pancreas: 145041.3" "Cell type enriched" "Detected in some" 213 "Pancreatic acinar cells: 865.3" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 1678 "Pancreatic Adenocarcinoma (TCGA): 1235.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Exocrine glandular cells" "HPA045394, HPA045399, CAB045960, HPA046980" Enhanced Approved "Golgi apparatus,Cytosol" "Secreted to digestive system" Enzyme NA NA 82000000 "Cluster 8: Pancreas - Proteolysis" "Cluster 51: Neurons - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 5: Pancreatic acinar cells - Pancreatic exocrine secretion" 6 "Golgi apparatus, Cytosol" "CAB045960: , HPA045394: , HPA045399: , HPA046980: " "unprognostic (3.64e-1)" "unprognostic (1.95e-1)" "unprognostic (1.01e-1)" AMY2B AMY2 ENSG00000240038 "Amylase alpha 2B" P19961 1 103553815-103579534 "Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Carbohydrate metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 129 "pancreas: 33016.8" "Cell type enriched" "Detected in many" 17 "Pancreatic acinar cells: 2812.3" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 16 "Pancreatic Adenocarcinoma (TCGA): 228.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 5.3" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Pancreas - Exocrine glandular cells" "HPA045394, HPA045399, HPA046980" Supported Approved "Golgi apparatus,Cytosol" "Secreted to digestive system" Enzyme NA NA 78000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 8: Pancreas - Proteolysis" "Cluster 15: Non-specific - Transcription" "Cluster 56: Non-specific - Sensory perception" "Cluster 5: Pancreatic acinar cells - Pancreatic exocrine secretion" 2 "Golgi apparatus, Cytosol" "HPA045394: , HPA045399: , HPA046980: " "unprognostic (7.59e-3)" "unprognostic (1.20e-2)" "unprognostic (1.49e-1)" "unprognostic (1.56e-2)" "unprognostic (8.00e-2)" "unprognostic (2.27e-2)" "unprognostic (1.13e-1)" "potential prognostic favorable (4.78e-4)" "potential prognostic favorable (4.55e-4)" "unprognostic (4.15e-2)" "unprognostic (2.37e-3)" "unprognostic (3.85e-3)" "unprognostic (3.75e-2)" "unprognostic (1.94e-3)" "potential prognostic favorable (7.45e-5)" "unprognostic (3.47e-2)" "unprognostic (9.56e-2)" "unprognostic (1.02e-1)" "unprognostic (1.07e-1)" "unprognostic (4.19e-1)" "unprognostic (1.39e-1)" "unprognostic (5.71e-2)" "unprognostic (3.03e-2)" "unprognostic (2.74e-1)" "unprognostic (4.38e-2)" "potential prognostic favorable (6.43e-4)" "unprognostic (5.76e-2)" "unprognostic (4.38e-2)" "unprognostic (8.65e-3)" "unprognostic (3.44e-1)" "unprognostic (2.61e-1)" AMZ1 KIAA1950 ENSG00000174945 "Archaelysin family metallopeptidase 1" Q400G9 7 2679522-2775500 "Enzymes, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 2.1" "Cell type enhanced" "Detected in many" "Adipocytes: 88.0;B-cells: 68.6;Cardiomyocytes: 136.4;cDC: 87.6;Epicardial cells: 88.7;Fibro-adipogenic progenitors: 90.5;Oligodendrocyte progenitor cells: 242.4;Syncytiotrophoblasts: 72.8;Thymocytes: 77.1" "Group enriched" "Detected in all" 4 "committed oligodendrocyte precursor: 104.8;oligodendrocyte precursor cell: 300.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.3" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in some" "Kidney cancer: 4.8;thyroid cancer: 4.7" "Pituitary gland - Gonadotropes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020233 Uncertain NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 73: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 17 "HPA020233: " "unprognostic (7.04e-2)" "unprognostic (7.27e-2)" "unprognostic (2.38e-2)" "unprognostic (9.22e-3)" "unprognostic (1.02e-1)" "unprognostic (8.13e-3)" "unprognostic (9.53e-2)" "unprognostic (8.71e-2)" AMZ2 ENSG00000196704 "Archaelysin family metallopeptidase 2" Q86W34 17 68205481-68257712 "Enzymes, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 471.8;Choroid plexus epithelial cells: 277.8;Early spermatids: 499.4;Ependymal cells: 390.3;Late primary spermatocytes: 550.6;Late spermatids: 2072.4;Müller glia: 273.5" "Cell type enhanced" "Detected in all" "astrocyte: 432.5;ependymal cell: 373.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023299, HPA052406" Enhanced Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 28: Astrocytes - Homeostasis & neuron support" 1 Nucleoplasm "Nuclear bodies, Cytosol" "HPA023299: , HPA052406: " "unprognostic (1.47e-1)" "unprognostic (6.31e-2)" "unprognostic (2.48e-1)" "unprognostic (1.45e-1)" "unprognostic (3.83e-2)" "unprognostic (1.28e-1)" "unprognostic (2.76e-1)" "unprognostic (1.08e-1)" "potential prognostic unfavorable (8.09e-4)" "potential prognostic unfavorable (7.10e-4)" "potential prognostic favorable (1.72e-5)" "unprognostic (1.26e-1)" "unprognostic (6.06e-2)" "potential prognostic unfavorable (3.98e-5)" "unprognostic (6.54e-3)" "unprognostic (1.44e-1)" "unprognostic (2.43e-2)" "unprognostic (3.98e-1)" "unprognostic (1.14e-1)" "unprognostic (2.19e-2)" "unprognostic (2.83e-1)" "potential prognostic favorable (9.90e-4)" "unprognostic (2.15e-1)" "unprognostic (3.05e-1)" "unprognostic (3.71e-3)" "unprognostic (2.88e-2)" "unprognostic (1.40e-1)" "unprognostic (2.73e-1)" "unprognostic (2.25e-1)" "unprognostic (5.64e-2)" "unprognostic (3.78e-1)" ANAPC1 "APC1, MCPR, TSG24" ENSG00000153107 "Anaphase promoting complex subunit 1" Q9H1A4 2 111611639-111884690 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Cancer-related genes, Dwarfism, Ectodermal dysplasia, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 152.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036329, HPA036330, HPA042998" Approved Approved Vesicles NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 67 Vesicles "HPA036329: , HPA036330: , HPA042998: " "unprognostic (1.30e-2)" "unprognostic (1.22e-1)" "unprognostic (1.63e-1)" "unprognostic (1.36e-2)" "unprognostic (8.78e-2)" "unprognostic (3.61e-2)" "unprognostic (3.68e-1)" "unprognostic (1.06e-1)" "unprognostic (2.53e-1)" "unprognostic (1.29e-1)" "potential prognostic favorable (6.68e-4)" "unprognostic (6.47e-2)" "unprognostic (5.06e-2)" "potential prognostic unfavorable (4.09e-4)" "unprognostic (1.42e-2)" "unprognostic (3.50e-2)" "unprognostic (6.45e-2)" "unprognostic (2.26e-1)" "unprognostic (1.15e-2)" "unprognostic (2.97e-1)" "unprognostic (2.46e-2)" "unprognostic (7.36e-3)" "unprognostic (2.72e-2)" "unprognostic (1.60e-1)" "unprognostic (1.94e-3)" "unprognostic (1.03e-2)" "unprognostic (3.31e-1)" "unprognostic (4.76e-2)" "unprognostic (1.64e-1)" "unprognostic (1.58e-2)" "unprognostic (1.40e-1)" ANAPC10 "APC10, DKFZP564L0562, DOC1" ENSG00000164162 "Anaphase promoting complex subunit 10" Q9UM13 4 144831908-145098541 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 105.7;Epicardial cells: 34.1;Late primary spermatocytes: 33.7;Loop of henle epithelial cells: 68.9;Papillary tip epithelial cells: 44.3;Podocytes: 88.0;Proximal tubule cells: 73.5;Renal collecting duct intercalated cells: 78.5;Renal collecting duct principal cells: 53.7;Renal connecting tubule cells: 78.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044547 Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 105: Non-specific - Mixed function" 45 Nucleoplasm "Golgi apparatus" "HPA044547: " "unprognostic (3.18e-2)" "unprognostic (1.01e-2)" "unprognostic (1.93e-2)" "unprognostic (2.09e-1)" "unprognostic (1.58e-1)" "unprognostic (9.88e-3)" "unprognostic (3.18e-2)" "unprognostic (2.96e-1)" "unprognostic (2.25e-3)" "unprognostic (2.53e-3)" "potential prognostic favorable (7.59e-4)" "unprognostic (1.08e-2)" "unprognostic (3.67e-2)" "potential prognostic unfavorable (1.23e-4)" "unprognostic (1.07e-1)" "unprognostic (6.18e-2)" "unprognostic (1.59e-1)" "unprognostic (6.55e-2)" "unprognostic (1.33e-2)" "unprognostic (2.49e-1)" "unprognostic (3.20e-2)" "unprognostic (1.21e-1)" "potential prognostic unfavorable (1.81e-4)" "unprognostic (6.64e-2)" "unprognostic (9.27e-2)" "unprognostic (1.04e-1)" "unprognostic (1.93e-2)" "unprognostic (1.49e-1)" "unprognostic (3.59e-1)" "unprognostic (1.11e-1)" "unprognostic (1.37e-1)" ANAPC11 "APC11, Apc11p, HSPC214, MGC882" ENSG00000141552 "Anaphase promoting complex subunit 11" Q9NYG5 17 81890790-81900991 "Essential proteins, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 766.4;Extravillous trophoblasts: 655.6;Late primary spermatocytes: 854.1;Late spermatids: 1837.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021989, HPA027838" Approved Enhanced Nucleoplasm,Nucleoli Yes No "Cluster 10: Non-specific - Membrane trafficking" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 30 Nucleoplasm Nucleoli "HPA021989: , HPA027838: " "unprognostic (1.54e-1)" "unprognostic (6.29e-2)" "unprognostic (5.96e-2)" "unprognostic (9.72e-3)" "unprognostic (6.73e-2)" "unprognostic (4.17e-2)" "unprognostic (7.63e-2)" "unprognostic (2.46e-1)" "unprognostic (8.56e-2)" "unprognostic (1.17e-2)" "unprognostic (5.01e-2)" "potential prognostic unfavorable (8.78e-4)" "unprognostic (9.71e-2)" "unprognostic (1.05e-2)" "potential prognostic unfavorable (2.98e-9)" "unprognostic (4.79e-2)" "unprognostic (3.34e-2)" "unprognostic (5.29e-2)" "unprognostic (1.75e-1)" "unprognostic (8.77e-3)" "unprognostic (8.13e-2)" "unprognostic (1.41e-1)" "unprognostic (1.26e-1)" "unprognostic (1.10e-1)" "unprognostic (4.28e-1)" "unprognostic (1.44e-2)" "unprognostic (8.15e-2)" "unprognostic (9.24e-2)" "unprognostic (1.28e-1)" "unprognostic (1.02e-1)" "unprognostic (1.83e-1)" ANAPC13 "APC13, DKFZP566D193, SWM1" ENSG00000129055 "Anaphase promoting complex subunit 13" Q9BS18 3 134477706-134486716 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Gastric chief cells: 207.5;Oocytes: 198.0;Parietal cells: 279.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046114 Uncertain Approved Mitochondria,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 76: Non-specific - Metabolism" "Cluster 36: Choroid plexus - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 97: Non-specific - Cellular respiration" 39 "Mitochondria, Cytosol" "HPA046114: " "unprognostic (8.54e-2)" "unprognostic (2.56e-2)" "unprognostic (1.34e-1)" "unprognostic (1.99e-2)" "unprognostic (2.23e-1)" "unprognostic (2.19e-3)" "unprognostic (9.36e-2)" "unprognostic (1.64e-1)" "unprognostic (8.00e-2)" "unprognostic (3.97e-2)" "potential prognostic favorable (5.98e-6)" "unprognostic (2.28e-1)" "potential prognostic favorable (1.28e-5)" "validated prognostic unfavorable (1.23e-6)" "validated prognostic unfavorable (4.01e-4)" "unprognostic (1.88e-2)" "unprognostic (5.71e-2)" "unprognostic (7.32e-2)" "unprognostic (2.60e-1)" "unprognostic (1.29e-3)" "unprognostic (5.54e-3)" "unprognostic (7.56e-2)" "unprognostic (2.19e-1)" "unprognostic (1.56e-1)" "unprognostic (2.20e-1)" "unprognostic (1.25e-1)" "unprognostic (2.38e-1)" "unprognostic (2.21e-1)" "unprognostic (6.13e-2)" "unprognostic (1.04e-1)" "unprognostic (2.05e-1)" ANAPC15 "APC15, C11orf51, DKFZP564M082, HSPC020" ENSG00000110200 "Anaphase promoting complex subunit 15" P60006 11 72106378-72112780 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early primary spermatocytes: 137.9;Esophageal basal cells: 143.0;Undifferentiated spermatogonia: 128.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA036596 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 34: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 20 Nucleoplasm Vesicles "HPA036596: " "unprognostic (2.61e-1)" "unprognostic (1.21e-1)" "unprognostic (1.12e-1)" "unprognostic (1.58e-2)" "unprognostic (1.17e-2)" "unprognostic (5.51e-3)" "unprognostic (1.02e-1)" "unprognostic (1.81e-2)" "unprognostic (4.88e-2)" "unprognostic (6.08e-2)" "unprognostic (2.44e-1)" "potential prognostic favorable (5.21e-4)" "potential prognostic unfavorable (5.58e-5)" "unprognostic (1.66e-1)" "unprognostic (4.23e-2)" "unprognostic (6.83e-2)" "unprognostic (2.23e-1)" "unprognostic (1.94e-3)" "unprognostic (2.23e-1)" "unprognostic (4.35e-2)" "unprognostic (3.40e-1)" "unprognostic (2.04e-1)" "unprognostic (2.67e-2)" "unprognostic (1.78e-2)" "unprognostic (1.08e-1)" "unprognostic (6.51e-2)" "unprognostic (7.27e-2)" "unprognostic (1.41e-1)" "unprognostic (1.48e-1)" ANAPC16 "APC16, bA570G20.3, C10orf104, CENP-27, FLJ33728" ENSG00000166295 "Anaphase promoting complex subunit 16" Q96DE5 10 72216000-72235860 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037815 Approved Supported Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 54: Immune cells - T cell receptor" "Cluster 52: Non-specific - Mitochondria" "Cluster 15: Non-specific - Protein processing" 79 Cytosol "HPA037815: " "potential prognostic favorable (2.46e-4)" "unprognostic (1.34e-2)" "unprognostic (2.71e-1)" "unprognostic (6.44e-2)" "unprognostic (1.40e-2)" "unprognostic (3.21e-1)" "unprognostic (9.09e-2)" "unprognostic (9.27e-3)" "unprognostic (1.77e-2)" "unprognostic (1.76e-2)" "potential prognostic favorable (2.15e-6)" "unprognostic (2.73e-3)" "unprognostic (1.77e-3)" "unprognostic (1.66e-1)" "unprognostic (1.29e-1)" "unprognostic (8.96e-2)" "unprognostic (5.85e-2)" "unprognostic (8.90e-2)" "unprognostic (3.15e-1)" "unprognostic (1.54e-1)" "unprognostic (1.13e-1)" "unprognostic (1.37e-1)" "unprognostic (3.06e-2)" "unprognostic (2.10e-1)" "unprognostic (2.98e-1)" "unprognostic (1.23e-2)" "unprognostic (3.24e-2)" "unprognostic (2.24e-1)" "unprognostic (3.83e-2)" "unprognostic (6.18e-2)" "potential prognostic favorable (9.13e-5)" ANAPC2 "APC2, KIAA1406" ENSG00000176248 "Anaphase promoting complex subunit 2" Q9UJX6 9 137174784-137188560 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Mitosis, Neurogenesis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 39.3;Late primary spermatocytes: 57.1;Late spermatids: 85.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018692, HPA066539" Enhanced Supported Nucleoplasm,Mitochondria NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 24: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 91 Nucleoplasm Mitochondria "CAB018692: , HPA066539: " "unprognostic (2.15e-1)" "unprognostic (1.72e-2)" "unprognostic (9.02e-2)" "potential prognostic favorable (3.48e-4)" "unprognostic (7.15e-2)" "unprognostic (3.94e-2)" "unprognostic (2.82e-1)" "unprognostic (1.35e-3)" "unprognostic (2.10e-2)" "unprognostic (1.25e-1)" "potential prognostic favorable (7.32e-7)" "unprognostic (1.50e-2)" "potential prognostic favorable (4.04e-4)" "unprognostic (2.78e-1)" "unprognostic (1.77e-1)" "unprognostic (8.78e-2)" "unprognostic (2.67e-1)" "unprognostic (6.57e-2)" "unprognostic (9.69e-2)" "unprognostic (2.06e-1)" "unprognostic (3.03e-2)" "potential prognostic favorable (1.23e-4)" "unprognostic (7.17e-2)" "unprognostic (1.73e-1)" "unprognostic (1.31e-1)" "potential prognostic favorable (3.07e-4)" "unprognostic (8.55e-2)" "unprognostic (1.04e-2)" "unprognostic (4.12e-2)" "unprognostic (6.17e-3)" "unprognostic (1.23e-2)" ANAPC4 APC4 ENSG00000053900 "Anaphase promoting complex subunit 4" Q9UJX5 4 25377263-25418498 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Endometrial ciliated cells: 686.5;Fallopian tube ciliated cells: 355.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032519, HPA038395, HPA038396" Approved NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 75: Ovary - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 91 "CAB032519: , HPA038395: , HPA038396: " "unprognostic (1.29e-1)" "unprognostic (4.14e-2)" "potential prognostic favorable (7.11e-4)" "unprognostic (2.04e-1)" "unprognostic (2.22e-2)" "unprognostic (1.70e-3)" "unprognostic (1.98e-1)" "unprognostic (8.00e-3)" "unprognostic (1.80e-2)" "unprognostic (1.06e-2)" "unprognostic (5.37e-2)" "unprognostic (1.34e-2)" "unprognostic (2.36e-3)" "potential prognostic unfavorable (8.15e-5)" "unprognostic (1.90e-1)" "unprognostic (8.35e-2)" "unprognostic (3.87e-2)" "unprognostic (2.12e-1)" "unprognostic (2.36e-2)" "unprognostic (1.93e-1)" "unprognostic (1.02e-1)" "unprognostic (2.06e-1)" "unprognostic (3.43e-3)" "unprognostic (2.45e-1)" "potential prognostic favorable (1.74e-4)" "unprognostic (2.93e-1)" "unprognostic (3.66e-2)" "unprognostic (1.01e-1)" "unprognostic (1.63e-1)" "unprognostic (1.69e-2)" "unprognostic (2.52e-2)" ANAPC5 APC5 ENSG00000089053 "Anaphase promoting complex subunit 5" Q9UJX4 12 121308245-121399896 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039457, HPA039801" Supported Approved Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 47: Platelets - Hemostasis" 67 Nucleoplasm "HPA039457: , HPA039801: " "unprognostic (2.43e-1)" "unprognostic (1.90e-2)" "unprognostic (2.29e-1)" "unprognostic (3.57e-2)" "unprognostic (1.29e-2)" "unprognostic (8.37e-2)" "unprognostic (2.64e-1)" "unprognostic (1.73e-3)" "unprognostic (1.06e-1)" "unprognostic (1.05e-2)" "potential prognostic favorable (2.00e-4)" "unprognostic (5.12e-3)" "unprognostic (9.45e-2)" "unprognostic (8.45e-3)" "unprognostic (2.14e-3)" "unprognostic (1.15e-1)" "unprognostic (7.40e-2)" "unprognostic (1.21e-1)" "unprognostic (1.73e-2)" "unprognostic (6.94e-2)" "unprognostic (4.79e-3)" "unprognostic (5.84e-2)" "unprognostic (7.47e-3)" "unprognostic (7.18e-2)" "validated prognostic favorable (3.51e-4)" "validated prognostic favorable (9.73e-4)" "unprognostic (5.72e-2)" "unprognostic (3.29e-1)" "unprognostic (1.01e-1)" "unprognostic (9.81e-2)" "unprognostic (3.40e-1)" ANAPC7 APC7 ENSG00000196510 "Anaphase promoting complex subunit 7" Q9UJX3 12 110372900-110403730 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal suprabasal cells: 87.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009567, HPA070008" Approved Supported "Nucleoplasm,Vesicles,Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 39: Testis - Nuclear processes" "Cluster 14: Neurons - Synaptic function" "Cluster 38: Non-specific - Transcription" "Cluster 85: Squamous epithelial cells - Keratinization" 56 "Microtubules, Cytokinetic bridge, Mitotic spindle" "Nucleoplasm, Vesicles" "CAB009567: , HPA070008: " "unprognostic (1.91e-1)" "unprognostic (8.81e-3)" "unprognostic (2.11e-1)" "unprognostic (1.75e-1)" "unprognostic (7.60e-3)" "unprognostic (6.91e-2)" "unprognostic (2.82e-1)" "unprognostic (4.25e-3)" "unprognostic (3.00e-1)" "unprognostic (1.52e-3)" "potential prognostic favorable (6.27e-4)" "unprognostic (1.45e-1)" "unprognostic (6.89e-2)" "potential prognostic unfavorable (1.30e-7)" "unprognostic (1.02e-3)" "unprognostic (1.26e-3)" "unprognostic (1.97e-1)" "unprognostic (1.17e-1)" "unprognostic (1.22e-3)" "unprognostic (1.69e-1)" "unprognostic (3.93e-1)" "unprognostic (8.47e-2)" "potential prognostic unfavorable (4.78e-4)" "unprognostic (3.55e-2)" "unprognostic (3.53e-1)" "unprognostic (1.47e-1)" "unprognostic (2.08e-1)" "unprognostic (1.95e-1)" "unprognostic (5.56e-2)" "unprognostic (1.21e-1)" "unprognostic (7.38e-3)" ANG "RAA1, RNASE5" ENSG00000214274 Angiogenin P03950 14 20684177-20698971 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Angiogenesis, Differentiation, Stress response" "Developmental protein, DNA-binding, Endonuclease, Hydrolase, Nuclease, Protein synthesis inhibitor" "Amyotrophic lateral sclerosis, Cancer-related genes, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 50 "liver: 2816.4" "Cell type enriched" "Detected in some" 12 "Hepatocytes: 28.6" "Not detected" "Not detected" "Cancer enriched" "Detected in all" 16 "Liver Hepatocellular Carcinoma (TCGA): 832.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 24.6;myeloid DC: 14.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Liver - Hepatocytes, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055896 Approved "Nucleoli,Nucleoli rim,Mitotic chromosome,Actin filaments" "Secreted to blood" "Developmental protein" Yes No 308000000 290000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 39: Astrocytes - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 93: Hepatocytes - Bile production & excretion" 8 "Nucleoli, Nucleoli rim, Mitotic chromosome" "Actin filaments" "HPA055896: " "unprognostic (1.19e-1)" "unprognostic (3.18e-1)" "unprognostic (3.94e-2)" "unprognostic (2.67e-2)" "unprognostic (1.24e-1)" "unprognostic (2.28e-1)" "potential prognostic unfavorable (6.12e-4)" "unprognostic (1.03e-2)" "unprognostic (6.63e-2)" "unprognostic (3.33e-2)" "validated prognostic favorable (3.36e-5)" "validated prognostic favorable (1.49e-5)" "unprognostic (3.77e-2)" "validated prognostic favorable (6.44e-5)" "validated prognostic favorable (5.12e-4)" "unprognostic (7.07e-2)" "unprognostic (2.40e-1)" "unprognostic (4.10e-2)" "unprognostic (1.98e-1)" "unprognostic (9.17e-2)" "unprognostic (1.14e-1)" "unprognostic (2.95e-1)" "unprognostic (1.50e-2)" "unprognostic (3.32e-1)" "unprognostic (2.61e-1)" "potential prognostic unfavorable (5.52e-7)" "unprognostic (4.00e-2)" "unprognostic (1.25e-2)" "unprognostic (1.09e-1)" "unprognostic (8.43e-2)" "unprognostic (5.96e-2)" ANGEL1 "Ccr4e, KIAA0759" ENSG00000013523 "Angel homolog 1" Q9UNK9 14 76786009-76826246 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 116.7;Late spermatids: 130.7;Microglia: 84.6;Oligodendrocyte progenitor cells: 116.7;Sertoli cells: 90.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Endothelial cells, Skin - Endothelial cells, Spleen - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000948 Uncertain Approved Nucleoplasm "Intracellular and membrane" "No annotated function" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 21: Testis - Mixed function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 8 Nucleoplasm "HPA000948: " "unprognostic (1.30e-1)" "unprognostic (9.82e-3)" "unprognostic (1.69e-1)" "unprognostic (1.39e-2)" "unprognostic (3.02e-1)" "unprognostic (3.06e-1)" "unprognostic (2.07e-1)" "potential prognostic favorable (5.75e-4)" "unprognostic (1.21e-1)" "unprognostic (1.03e-1)" "unprognostic (4.88e-2)" "unprognostic (4.85e-3)" "unprognostic (2.85e-2)" "unprognostic (1.13e-1)" "unprognostic (1.98e-1)" "unprognostic (2.09e-2)" "unprognostic (1.48e-2)" "unprognostic (3.02e-2)" "unprognostic (2.61e-1)" "unprognostic (2.34e-1)" "unprognostic (1.93e-1)" "unprognostic (2.70e-3)" "unprognostic (1.44e-2)" "unprognostic (3.13e-1)" "unprognostic (4.22e-2)" "unprognostic (5.99e-2)" "unprognostic (4.95e-3)" "unprognostic (9.86e-2)" "unprognostic (4.92e-1)" "unprognostic (3.45e-2)" "unprognostic (1.26e-1)" ANGEL2 "Ccr4d, FLJ12793, KIAA0759L" ENSG00000174606 "Angel homolog 2" Q5VTE6 1 212992182-213015867 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030795, HPA030796" Uncertain Approved "Nucleoplasm,Nuclear bodies,Mitochondria" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 65: Brain - Transcription" "Cluster 33: Neurons - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 4 Nucleoplasm "Nuclear bodies, Mitochondria" "HPA030795: , HPA030796: " "unprognostic (4.68e-3)" "unprognostic (4.25e-2)" "unprognostic (7.58e-2)" "unprognostic (6.63e-2)" "unprognostic (2.90e-1)" "unprognostic (2.07e-1)" "unprognostic (8.49e-2)" "unprognostic (2.29e-3)" "unprognostic (7.29e-3)" "unprognostic (1.28e-1)" "unprognostic (1.74e-2)" "unprognostic (1.74e-1)" "unprognostic (1.08e-1)" "unprognostic (8.88e-2)" "unprognostic (3.53e-1)" "unprognostic (3.09e-1)" "unprognostic (3.45e-1)" "unprognostic (8.16e-2)" "unprognostic (3.28e-1)" "unprognostic (2.89e-2)" "potential prognostic unfavorable (6.27e-4)" "unprognostic (9.10e-3)" "unprognostic (4.16e-2)" "unprognostic (8.79e-2)" "unprognostic (1.37e-2)" "unprognostic (1.42e-1)" "unprognostic (6.33e-2)" "unprognostic (7.39e-2)" "unprognostic (1.59e-1)" "unprognostic (7.80e-3)" "unprognostic (7.54e-2)" ANGPT1 "AGPT-1, Ang1, KIAA0003" ENSG00000154188 "Angiopoietin 1" Q15389 8 107249482-107498055 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 31.7" "Cell type enhanced" "Detected in many" "Adipocytes: 461.8;Bergmann glia: 326.9;Ependymal cells: 262.4;Fibro-adipogenic progenitors: 176.0;Hematopoietic stem cells: 576.9;Lactotrophs: 512.2;Megakaryocyte progenitors: 636.7;Megakaryocyte-Erythroid progenitors: 212.6;Myonuclei: 375.5;Renal connecting tubule cells: 192.8;Vascular smooth muscle cells: 219.9" "Cell type enhanced" "Detected in many" "Bergmann glia: 398.6;cerebellar inhibitory: 306.4;vascular associated smooth muscle cell: 338.2" "Cancer enriched" "Detected in many" 4 "Kidney Chromophobe (TCGA): 24.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "neutrophil: 5.8" "Lineage enriched" "Detected in many" 5 "granulocytes: 5.8" "Cancer enhanced" "Detected in many" "Rhabdoid: 45.3" "Adrenal gland - Fibroblasts, Heart muscle - Smooth muscle cells, Liver - Hepatic stellate cells, Lung - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017815, HPA018793, HPA018816" Approved "Secreted to blood" "Developmental protein" NA NA 32000000 120000 "Cluster 28: Neutrophils - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 55: Non-specific - Transcription" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 89: Adipocytes - Lipid metabolism" 11 "CAB017815: , HPA018793: , HPA018816: " "unprognostic (1.04e-1)" "unprognostic (1.46e-1)" "unprognostic (1.23e-1)" "unprognostic (1.56e-1)" "unprognostic (2.44e-1)" "unprognostic (1.39e-1)" "unprognostic (3.54e-3)" "unprognostic (5.41e-3)" "unprognostic (2.05e-2)" "validated prognostic favorable (6.83e-6)" "validated prognostic favorable (1.12e-4)" "unprognostic (2.45e-2)" "unprognostic (1.95e-3)" "unprognostic (1.18e-1)" "potential prognostic favorable (9.50e-4)" "unprognostic (2.90e-3)" "unprognostic (5.16e-3)" "unprognostic (3.05e-2)" "unprognostic (2.13e-1)" "unprognostic (3.32e-1)" "unprognostic (1.06e-1)" "unprognostic (6.57e-2)" "unprognostic (2.54e-2)" "unprognostic (2.13e-2)" "potential prognostic unfavorable (9.02e-4)" "unprognostic (2.07e-1)" "unprognostic (1.03e-1)" "unprognostic (6.72e-3)" ANGPT2 Ang2 ENSG00000091879 "Angiopoietin 2" O15123 8 6499632-6563409 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 111.1;Cardiomyocytes: 198.1;Epicardial cells: 263.8;Lymphatic endothelial cells: 553.9;Myonuclei: 110.9;Pericytes: 152.8;Vascular endothelial cells: 149.6;Vascular smooth muscle cells: 126.4" "Cell type enhanced" "Detected in all" "endothelial cell: 236.5" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 44.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.6" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "ovarian cancer: 10.4" "Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Liver - Vascular endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB011437, CAB017626" Approved "Secreted to blood" "Developmental protein" NA NA 3780000 340000 "Cluster 34: B-cells - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 49: Hindbrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 5 "CAB011437: , CAB017626: " "unprognostic (8.64e-2)" "unprognostic (6.31e-2)" "unprognostic (3.30e-2)" "potential prognostic unfavorable (2.43e-4)" "unprognostic (2.31e-1)" "unprognostic (2.16e-1)" "unprognostic (2.02e-1)" "unprognostic (2.07e-2)" "unprognostic (1.88e-1)" "unprognostic (4.94e-3)" "unprognostic (9.20e-3)" "unprognostic (1.42e-2)" "potential prognostic unfavorable (1.27e-4)" "validated prognostic unfavorable (7.06e-5)" "validated prognostic unfavorable (4.83e-5)" "unprognostic (2.51e-2)" "unprognostic (2.45e-3)" "unprognostic (3.96e-2)" "unprognostic (1.68e-1)" "unprognostic (6.85e-2)" "unprognostic (2.02e-3)" "unprognostic (4.40e-3)" "unprognostic (3.32e-2)" "unprognostic (1.16e-1)" "unprognostic (8.78e-2)" "unprognostic (8.55e-2)" "unprognostic (2.11e-3)" "potential prognostic unfavorable (4.53e-4)" "unprognostic (2.59e-1)" "unprognostic (8.48e-3)" "unprognostic (4.03e-2)" ANGPT4 ENSG00000101280 "Angiopoietin 4" Q9Y264 20 869900-916334 "Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 6.9;breast: 6.5" "Cell type enhanced" "Detected in some" "Adipocytes: 9.8;Extravillous trophoblasts: 94.4;Late spermatids: 29.9;Pericytes: 21.2;Vascular smooth muscle cells: 48.2" "Cell type enriched" "Detected in some" 4 "vascular associated smooth muscle cell: 14.3" "Cancer enhanced" "Detected in single" "Bladder Urothelial Carcinoma (TCGA): 1.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB013260, CAB013305" Uncertain "Secreted to blood" "Developmental protein" NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 6: Non-specific - Immune response" "Cluster 34: Testis cancer - Unknown function" "Cluster 110: Mural cells - ECM organization" "CAB013260: , CAB013305: " "potential prognostic unfavorable (4.62e-4)" ANGPTL1 "ANG3, ANGPT3, AngY, ARP1" ENSG00000116194 "Angiopoietin like 1" O95841 1 178849535-178871077 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 125.3" "Cell type enhanced" "Detected in many" "B-cells: 280.9;Decidual stromal cells: 205.5;Esophageal apical cells: 190.0;Foveolar cells: 185.4;Hepatic stellate cells: 187.2;Leydig cells: 575.1;Ovarian stromal cells: 188.5;Peritubular myoid cells: 298.5;Rod photoreceptor cells: 217.3" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 15.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 3.1" "Adrenal gland - Adrenal cortex cells, Breast - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Minor Salivary Gland - Fibroblasts, Skin - Fibroblasts_2, Spleen - Fibroblasts_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA009976 Approved "Secreted to blood" "No annotated function" NA NA 8000000 110000 "Cluster 34: B-cells - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 29: Forebrain - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 87: B-cells - Adaptive immunity: Humoral response" "HPA009976: " "unprognostic (1.77e-1)" "unprognostic (6.59e-2)" "unprognostic (2.07e-1)" "unprognostic (3.41e-2)" "unprognostic (1.06e-1)" "unprognostic (3.54e-1)" "unprognostic (1.12e-2)" "unprognostic (8.22e-3)" "unprognostic (1.49e-2)" "unprognostic (1.55e-2)" "unprognostic (1.52e-1)" "unprognostic (2.48e-3)" "potential prognostic favorable (1.26e-5)" "unprognostic (1.66e-1)" "unprognostic (2.34e-2)" "unprognostic (1.00e-1)" "unprognostic (4.27e-2)" "unprognostic (4.81e-2)" "unprognostic (1.46e-1)" "unprognostic (3.97e-1)" "unprognostic (3.26e-2)" "unprognostic (1.68e-2)" "unprognostic (2.43e-3)" "unprognostic (5.26e-2)" "unprognostic (1.44e-2)" "unprognostic (5.24e-2)" ANGPTL2 "ARP2, HARP" ENSG00000136859 "Angiopoietin like 2" Q9UKU9 9 127087348-127122635 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 53.3;Cardiomyocytes: 61.4;Choroid plexus epithelial cells: 40.8;Decidual stromal cells: 91.9;Fibro-adipogenic progenitors: 75.3;Fibroblasts: 72.6;Mesothelial cells: 52.3;Oligodendrocyte progenitor cells: 57.3;Oligodendrocytes: 43.3;Smooth muscle cells: 67.8" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 132.6;oligodendrocyte precursor cell: 69.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 24.6" "Adrenal gland - Fibroblasts, Liver - Hepatic stellate cells, Minor Salivary Gland - Endothelial cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040933, HPA041299" Approved Approved "Golgi apparatus" "Secreted to blood" "No annotated function" NA NA 2510000 1600000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 1 "Golgi apparatus" "HPA040933: , HPA041299: " "unprognostic (5.30e-2)" "unprognostic (2.80e-2)" "unprognostic (1.70e-1)" "unprognostic (1.40e-2)" "unprognostic (1.49e-2)" "unprognostic (4.00e-1)" "unprognostic (2.14e-1)" "unprognostic (8.21e-2)" "unprognostic (1.94e-2)" "unprognostic (2.37e-2)" "unprognostic (4.10e-2)" "unprognostic (1.87e-2)" "unprognostic (1.02e-1)" "unprognostic (9.18e-3)" "unprognostic (2.27e-1)" "unprognostic (9.12e-2)" "unprognostic (1.69e-2)" "unprognostic (2.48e-2)" "unprognostic (3.92e-2)" "unprognostic (1.43e-3)" "unprognostic (2.23e-3)" "unprognostic (2.87e-2)" "unprognostic (1.23e-1)" "unprognostic (1.98e-2)" "unprognostic (6.24e-2)" "unprognostic (4.31e-2)" "unprognostic (7.97e-2)" "unprognostic (2.03e-3)" "unprognostic (3.44e-1)" "potential prognostic unfavorable (9.15e-4)" "unprognostic (1.64e-2)" ANGPTL3 ANGPT5 ENSG00000132855 "Angiopoietin like 3" Q9Y5C1 1 62597520-62606313 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion, Lipid metabolism" Heparin-binding "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "liver: 631.8" "Cell type enriched" "Detected in some" 7 "Hepatocytes: 655.2" "Cell type enhanced" "Detected in single" "astrocyte: 1.4" "Cancer enriched" "Detected in some" 24 "Liver Hepatocellular Carcinoma (TCGA): 124.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 39 "liver cancer: 9.2" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Liver - Hepatocytes, Stomach - Parietal cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA038097 Approved "Secreted to blood" "Cell adhesion" NA NA 225000000 64000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 31: Non-specific - Transcription" "Cluster 18: Liver cancer - Metabolism" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" "HPA038097: " "validated prognostic favorable (7.27e-6)" "validated prognostic favorable (4.89e-5)" "unprognostic (2.32e-2)" "unprognostic (6.44e-2)" "potential prognostic favorable (6.81e-5)" "unprognostic (8.64e-2)" "unprognostic (7.02e-2)" ANGPTL4 "ARP4, FIAF, HFARP, NL2, PGAR, pp1158" ENSG00000167772 "Angiopoietin like 4" Q9BY76 19 8363289-8374370 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Lipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 188.0;breast: 162.4;liver: 176.8" "Cell type enhanced" "Detected in many" "Adipocytes: 215.7;Astrocytes: 218.8;Breast lactating cells: 723.3;Enterocytes: 585.5;Esophageal apical cells: 999.9;Extravillous trophoblasts: 208.0;Hepatocytes: 220.5;Pancreatic acinar cells: 450.9;Prostatic club cells: 182.6;Urothelial cells: 194.2" "Cell type enriched" "Detected in many" 7 "astrocyte: 249.2" "Cancer enriched" "Detected in all" 8 "Kidney Renal Clear Cell Carcinoma (TCGA): 660.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 3.3" "Lineage enriched" "Detected in single" 11 "granulocytes: 3.3" "Cancer enhanced" "Detected in many" "Kidney cancer: 78.5" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA007879, CAB033770" Approved Approved Nucleoplasm,Vesicles "Secreted to blood" "Developmental protein" NA NA 7750000 910000 "Cluster 70: Non-specific - Protein processing" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 84: Apical squamous epithelium - Cornification" 12 "Nucleoplasm, Vesicles" "CAB033770: , HPA007879: " "unprognostic (2.43e-3)" "unprognostic (2.95e-1)" "potential prognostic favorable (1.29e-4)" "unprognostic (8.03e-3)" "unprognostic (3.17e-2)" "unprognostic (1.57e-1)" "unprognostic (2.54e-3)" "unprognostic (3.15e-2)" "unprognostic (3.36e-1)" "unprognostic (1.13e-1)" "potential prognostic favorable (6.02e-5)" "unprognostic (1.76e-1)" "unprognostic (1.26e-1)" "unprognostic (1.61e-2)" "unprognostic (5.28e-2)" "potential prognostic unfavorable (4.01e-5)" "unprognostic (3.23e-3)" "unprognostic (9.64e-2)" "unprognostic (1.68e-1)" "unprognostic (4.60e-3)" "unprognostic (2.40e-1)" "unprognostic (6.23e-3)" "potential prognostic unfavorable (1.72e-4)" "unprognostic (2.99e-1)" "unprognostic (1.96e-1)" "unprognostic (5.78e-2)" "unprognostic (2.57e-1)" "unprognostic (1.76e-3)" "unprognostic (1.02e-1)" "unprognostic (2.94e-2)" "unprognostic (2.96e-1)" ANGPTL5 ENSG00000187151 "Angiopoietin like 5" Q86XS5 11 101890674-101916522 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "ovary: 19.0" "Cell type enhanced" "Detected in many" "Adipocytes: 12.8;Decidual stromal cells: 15.2;Epicardial cells: 29.6;Fibroblasts: 33.2;Leydig cells: 27.5;Ovarian stromal cells: 68.7;Peritubular myoid cells: 16.3;Respiratory ciliated cells: 11.0" "Cell type enhanced" "Detected in many" "fibroblast: 34.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Fibroblasts, Skeletal muscle - Fibroblasts, Thyroid gland - Fibroblasts" "Region enhanced" "Detected in some" "spinal cord: 4.3" HPA038516 Uncertain "Secreted in other tissues" "No annotated function" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 1 "HPA038516: " ANGPTL6 "AGF, ARP5" ENSG00000130812 "Angiopoietin like 6" Q8NI99 19 10092338-10102678 "Plasma proteins, Predicted secreted proteins" "Angiogenesis, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "liver: 29.3" "Cell type enhanced" "Detected in some" "Adipocytes: 6.8;Differentiating spermatogonia: 6.2;Epicardial cells: 40.9;Granulosa cells: 15.4;Hepatic stellate cells: 19.4;Hepatocytes: 9.5;Megakaryocytes: 6.2;Oocytes: 9.2;Undifferentiated spermatogonia: 9.1" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 6.1" "Group enriched" "Detected in some" 5 "Glioblastoma Multiforme (TCGA): 2.0;Liver Hepatocellular Carcinoma (TCGA): 2.5;Prostate Adenocarcinoma (TCGA): 3.9;Testicular Germ Cell Tumor (TCGA): 4.6;Uterine Corpus Endometrial Carcinoma (TCGA): 6.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Leukemia: 13.2;lymphoma: 6.5" "Liver - Hepatic stellate cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Secreted to blood" "Developmental protein" NA NA 450000 33000000 "Cluster 16: Non-specific - Cell proliferation" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "unprognostic (3.72e-2)" "unprognostic (2.84e-1)" "unprognostic (3.61e-1)" "unprognostic (6.22e-2)" "unprognostic (4.54e-3)" "unprognostic (2.11e-1)" "unprognostic (2.91e-1)" "unprognostic (5.05e-2)" "unprognostic (1.77e-2)" ANGPTL7 "AngX, CDT6" ENSG00000171819 "Angiopoietin like 7" O43827 1 11189355-11195981 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 15.5;blood vessel: 17.5" "Cell type enhanced" "Detected in some" "Epicardial cells: 6.8;Fibroblasts: 43.4;Mesothelial cells: 9.8;Ocular epithelial cells: 12.0;Retinal ganglion cells: 11.6;Schwann cells: 44.3" "Cell type enhanced" "Detected in many" "fibroblast: 4.7" "Cancer enriched" "Detected in some" 16 "Skin Cutaneous Melanoma (TCGA): 32.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Adrenal gland - Fibroblasts, Colon - Enteric glia cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells" "Not detected" "Not detected" "Region enriched" "Detected in all" 13 "spinal cord: 82.5" "Secreted in other tissues" "No annotated function" NA NA 110000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 14 "unprognostic (1.50e-1)" "unprognostic (1.23e-1)" "unprognostic (1.05e-1)" "unprognostic (2.31e-1)" "unprognostic (5.38e-2)" "unprognostic (3.43e-2)" "unprognostic (8.36e-2)" ANGPTL8 "C19orf80, RIFL, TD26" ENSG00000130173 "Angiopoietin like 8" Q6UXH0 19 11237450-11241943 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Lipid metabolism" Hormone "Diabetes mellitus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "liver: 408.5" "Cell type enriched" "Detected in some" 15 "Hepatocytes: 109.0" "Cell type enhanced" "Detected in some" "pericyte: 1.5" "Cancer enriched" "Detected in some" 26 "Liver Hepatocellular Carcinoma (TCGA): 184.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 11 "liver cancer: 9.6" "Breast - Adipocytes (Breast), Minor Salivary Gland - Adipocytes (Minor salivary gland), Skin - Adipocytes (Skin)" "Not detected" "Not detected" "Not detected" "Not detected" HPA042131 Approved "Nucleoplasm,Golgi apparatus" "Secreted to blood" Hormone NA NA 836000 860000 "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 47: Endothelial cells - Vasculature" "Cluster 18: Liver cancer - Metabolism" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 1 "Golgi apparatus" Nucleoplasm "HPA042131: " "unprognostic (5.37e-2)" "potential prognostic unfavorable (1.46e-5)" "unprognostic (5.38e-2)" "unprognostic (2.49e-1)" "unprognostic (2.51e-1)" "unprognostic (3.83e-2)" ANHX ENSG00000227059 "Anomalous homeobox" E9PGG2 12 133218312-133235877 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 58 "testis: 5.7" "Group enriched" "Detected in some" 25 "Differentiating spermatogonia: 33.5;Early primary spermatocytes: 17.8;Undifferentiated spermatogonia: 18.7" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 55 "Testicular Germ Cell Tumor (TCGA): 9.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Spermatogonia" "Low region specificity" "Detected in all" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 5: Rhabdoid - Unknown function" "Cluster 106: Spermatogonia - Spermatogonial differentiation" "unprognostic (1.88e-1)" ANK1 "ANK, SPH1" ENSG00000029534 "Ankyrin 1" P16157 8 41653220-41896741 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Disease variant, Elliptocytosis, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "skeletal muscle: 922.8;tongue: 592.2" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 123.9;Cone photoreceptor cells: 157.3;Erythrocyte progenitors: 908.8;Erythrocytes: 183.4;Megakaryocyte progenitors: 119.8;Megakaryocyte-Erythroid progenitors: 441.9;Myonuclei: 311.2;Platelets: 197.3;Retinal amacrine cells: 297.4;Retinal ganglion cells: 502.2;Thymic myoid cells: 198.5" "Cell type enhanced" "Detected in many" "lower rhombic lip: 286.0;mammillary body: 298.3;upper rhombic lip: 286.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 9.5;naive B-cell: 7.8" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Leukemia: 44.6" "Breast - Endothelial cells, Heart muscle - Cardiomyocytes, Liver - Erythroid cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Spleen - Erythrocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004842, HPA056953" Supported Supported NA NA 19000000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 7 "HPA004842: , HPA056953: " "unprognostic (7.57e-2)" "unprognostic (1.53e-1)" "unprognostic (2.68e-1)" "unprognostic (5.07e-2)" "unprognostic (4.07e-3)" "potential prognostic unfavorable (3.35e-4)" "unprognostic (2.33e-1)" "unprognostic (3.05e-1)" "unprognostic (5.31e-3)" "unprognostic (2.77e-1)" "unprognostic (5.31e-3)" "unprognostic (1.17e-1)" "unprognostic (5.59e-3)" "unprognostic (2.71e-2)" "unprognostic (4.30e-1)" "unprognostic (1.37e-1)" "unprognostic (2.65e-2)" "unprognostic (1.21e-1)" "unprognostic (2.60e-1)" "unprognostic (2.39e-2)" "unprognostic (2.54e-1)" "unprognostic (2.63e-2)" "unprognostic (2.73e-1)" ANK2 "CFAP87, FAP87, LQT4" ENSG00000145362 "Ankyrin 2" Q01484 4 112818032-113384221 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Endocytosis, Protein transport, Transport" "Disease variant, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 118.1;skeletal muscle: 120.2" "Cell type enhanced" "Detected in many" "Astrocytes: 1654.3;Bergmann glia: 6456.2;Brain excitatory neurons: 1399.6;Brain inhibitory neurons: 1228.1;Ependymal cells: 1554.5;Myonuclei: 1069.4;Oligodendrocytes: 1582.7;Other brain neurons: 1483.3;Retinal ganglion cells: 2151.6;Retinal horizontal cells: 2652.5" "Cell type enhanced" "Detected in all" "Bergmann glia: 6675.2" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 51.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 43.8;Rhabdoid: 31.6" "Adipose subcutaneous - Adipose progenitor cells, Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Liver - Hepatic stellate cells, Lung - Fibroblasts_2, Prostate - Fibroblasts, Spleen - Fibroblasts_1, Testis - Early spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008007, CAB015178, HPA035970" Enhanced Approved Supported "Plasma membrane,Acrosome" NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 28: Astrocytes - Homeostasis & neuron support" 40 "Plasma membrane, Acrosome" "CAB015178: , HPA008007: , HPA035970: " "unprognostic (8.16e-2)" "unprognostic (1.58e-1)" "unprognostic (1.54e-3)" "potential prognostic favorable (7.08e-5)" "unprognostic (7.10e-2)" "unprognostic (3.36e-2)" "unprognostic (1.63e-1)" "unprognostic (1.97e-1)" "unprognostic (3.34e-1)" "unprognostic (3.43e-1)" "unprognostic (1.17e-1)" "unprognostic (9.71e-2)" "unprognostic (4.03e-3)" "unprognostic (1.78e-1)" "unprognostic (1.22e-3)" "unprognostic (6.01e-2)" "potential prognostic unfavorable (3.78e-4)" "unprognostic (2.16e-1)" "unprognostic (6.28e-2)" "unprognostic (1.64e-1)" "unprognostic (1.46e-3)" "unprognostic (2.10e-1)" "unprognostic (4.04e-2)" "unprognostic (5.85e-2)" "unprognostic (3.74e-2)" "unprognostic (5.89e-2)" "unprognostic (3.48e-3)" "unprognostic (1.75e-1)" "unprognostic (1.23e-3)" "unprognostic (3.31e-2)" ANK3 ENSG00000151150 "Ankyrin 3" Q12955 10 60026298-60733490 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Autism spectrum disorder, Cancer-related genes, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 1895.9;Oligodendrocytes: 2382.8;Renal collecting duct principal cells: 2941.0;Retinal bipolar cells: 1780.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Liver - Hepatic stellate cells, Lung - Alveolar cells type 2, Spleen - Fibroblasts_2, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013249, CAB015179, HPA038455" Enhanced Supported "Plasma membrane" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 37: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 16 "Plasma membrane" "CAB013249: , CAB015179: , HPA038455: " "unprognostic (2.14e-1)" "unprognostic (1.36e-1)" "unprognostic (3.27e-2)" "unprognostic (2.74e-1)" "unprognostic (8.25e-3)" "unprognostic (3.53e-1)" "unprognostic (3.84e-1)" "unprognostic (3.08e-3)" "unprognostic (3.43e-2)" "unprognostic (3.96e-2)" "validated prognostic favorable (1.47e-11)" "validated prognostic favorable (4.15e-4)" "unprognostic (8.65e-2)" "unprognostic (2.99e-1)" "unprognostic (9.38e-2)" "unprognostic (2.10e-1)" "unprognostic (6.76e-2)" "unprognostic (1.25e-1)" "unprognostic (1.08e-1)" "unprognostic (3.03e-2)" "unprognostic (1.73e-1)" "unprognostic (1.72e-1)" "unprognostic (3.56e-3)" "unprognostic (6.21e-2)" "unprognostic (3.11e-2)" "unprognostic (2.16e-2)" "unprognostic (1.85e-1)" "unprognostic (9.27e-2)" "unprognostic (3.01e-1)" "unprognostic (2.47e-2)" "unprognostic (4.12e-1)" ANKAR FLJ25415 ENSG00000151687 "Ankyrin and armadillo repeat containing" Q7Z5J8 2 189674290-189761193 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 8 "testis: 5.4" "Cell type enhanced" "Detected in many" "Fibro-adipogenic progenitors: 220.2" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA036168 Uncertain Approved "Nucleoplasm,Centriolar satellite" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 56: Non-specific - Sensory perception" "Cluster 7: Non-specific - Transcription" "Centriolar satellite" Nucleoplasm "HPA036168: " "unprognostic (8.06e-2)" "unprognostic (2.00e-1)" "unprognostic (5.25e-2)" "unprognostic (4.48e-1)" "unprognostic (3.27e-1)" "unprognostic (2.06e-2)" "unprognostic (9.47e-2)" ANKDD1A FLJ25870 ENSG00000166839 "Ankyrin repeat and death domain containing 1A" Q495B1 15 64911902-64958691 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 96.1;Adrenal cortex cells: 119.3;Astrocytes: 291.3;Bergmann glia: 414.7;Epicardial cells: 145.5;Leydig cells: 130.1;Müller glia: 99.8;Peritubular myoid cells: 155.1" "Group enriched" "Detected in all" 4 "astrocyte: 344.6;Bergmann glia: 431.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 3.1" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Myeloma: 10.0" "Prostate - Fibroblasts" "Low region specificity" "Detected in some" "Region enriched" "Detected in all" 5 "cerebellum: 16.2" HPA040757 Approved Approved Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 28: Astrocytes - Homeostasis & neuron support" 1 Nucleoplasm "HPA040757: " "unprognostic (3.50e-2)" "unprognostic (3.17e-2)" "unprognostic (9.56e-3)" "unprognostic (1.72e-1)" "unprognostic (1.28e-2)" "unprognostic (1.20e-1)" "unprognostic (2.74e-1)" "unprognostic (3.60e-1)" "unprognostic (3.71e-2)" "potential prognostic unfavorable (4.29e-5)" "potential prognostic unfavorable (7.50e-4)" "unprognostic (2.04e-1)" "unprognostic (2.86e-1)" "unprognostic (7.61e-3)" "unprognostic (2.23e-3)" "unprognostic (1.32e-2)" "unprognostic (2.21e-1)" "unprognostic (1.34e-1)" "potential prognostic favorable (4.69e-4)" "unprognostic (9.79e-2)" "unprognostic (1.28e-1)" "unprognostic (1.89e-3)" "unprognostic (1.90e-3)" "unprognostic (2.53e-1)" "unprognostic (9.82e-2)" "potential prognostic favorable (6.70e-5)" "unprognostic (5.25e-2)" "unprognostic (8.01e-2)" "unprognostic (2.26e-1)" "unprognostic (8.29e-3)" "unprognostic (1.61e-1)" ANKDD1B ENSG00000189045 "Ankyrin repeat and death domain containing 1B" A6NHY2 5 75611182-75681773 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "fallopian tube: 4.1" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 143.6;Endometrial ciliated cells: 85.4;Ependymal cells: 258.7;Epididymal efferent duct ciliated cells: 103.2;Fallopian tube ciliated cells: 134.2;Proximal tubule cells: 56.2;Renal collecting duct intercalated cells: 59.2;Respiratory ciliated cells: 173.5" "Cell type enhanced" "Detected in all" "ependymal cell: 270.2" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 5.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA059722 Uncertain NA NA "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 17: Choroid plexus - Cilium" "Cluster 15: Kidney cancer - Membrane components" "Cluster 34: Ciliated cells - Cilia assembly & function" "HPA059722: " "unprognostic (9.22e-2)" "unprognostic (2.60e-3)" "unprognostic (1.23e-1)" "unprognostic (3.80e-2)" "unprognostic (1.28e-3)" "unprognostic (4.67e-2)" "unprognostic (3.81e-3)" "unprognostic (8.89e-2)" "unprognostic (2.45e-2)" "unprognostic (1.09e-1)" "unprognostic (1.39e-2)" "unprognostic (1.91e-1)" "unprognostic (5.82e-2)" "unprognostic (3.43e-2)" "unprognostic (1.93e-2)" ANKEF1 "ANKRD5, dJ839B4.6, FLJ21669" ENSG00000132623 "Ankyrin repeat and EF-hand domain containing 1" Q9NU02 20 9986126-10058303 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 13.2" "Group enriched" "Detected in many" 10 "Early spermatids: 429.6;Late spermatids: 552.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Prostate - Prostate basal glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA041151 Approved Approved "Nucleoli fibrillar center,Plasma membrane,Cytosol" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 8: Pancreas - Proteolysis" "Cluster 16: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 10 "Nucleoli fibrillar center, Plasma membrane, Cytosol" "HPA041151: " "unprognostic (2.01e-1)" "unprognostic (7.00e-3)" "unprognostic (3.06e-2)" "unprognostic (4.18e-2)" "unprognostic (3.21e-1)" "unprognostic (2.40e-1)" "unprognostic (2.25e-1)" "unprognostic (5.76e-2)" "potential prognostic favorable (4.06e-4)" "unprognostic (2.26e-1)" "unprognostic (3.09e-1)" "unprognostic (1.27e-2)" "unprognostic (1.22e-3)" "unprognostic (1.98e-1)" "unprognostic (7.89e-2)" "unprognostic (1.18e-1)" "unprognostic (1.60e-1)" "unprognostic (1.49e-1)" "unprognostic (1.23e-1)" "unprognostic (5.42e-2)" "unprognostic (1.11e-1)" "unprognostic (3.41e-2)" "unprognostic (3.89e-1)" "unprognostic (2.91e-2)" "unprognostic (9.04e-2)" "potential prognostic unfavorable (2.22e-4)" "unprognostic (2.45e-1)" ANKFN1 FLJ38335 ENSG00000153930 "Ankyrin repeat and fibronectin type III domain containing 1" Q8N957 17 55882301-56517016 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 8.3;fallopian tube: 4.7" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 191.5;Astrocytes: 339.8;Endometrial ciliated cells: 279.2;Ependymal cells: 809.6;Fallopian tube ciliated cells: 409.3;Papillary tip epithelial cells: 177.8;Prostatic club cells: 176.7;Respiratory ciliated cells: 918.4" "Cell type enhanced" "Detected in all" "astrocyte: 507.6;ependymal cell: 887.9" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 2.7;Liver Hepatocellular Carcinoma (TCGA): 2.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 2.4" "Lung - Respiratory ciliated cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021566, HPA022538, HPA048953" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 34: Ciliated cells - Cilia assembly & function" Nucleoplasm "Plasma membrane" "HPA021566: , HPA022538: , HPA048953: " "unprognostic (3.56e-1)" "unprognostic (8.50e-2)" "unprognostic (3.79e-2)" "unprognostic (9.36e-2)" "unprognostic (1.39e-1)" "unprognostic (1.31e-1)" "unprognostic (1.22e-1)" "unprognostic (1.23e-1)" "unprognostic (5.20e-2)" ANKFY1 "ANKHZN, BTBD23, KIAA1255, RANK-5, ZFYVE14" ENSG00000185722 "Ankyrin repeat and FYVE domain containing 1" Q9P2R3 17 4163821-4263995 "Plasma proteins, Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Thymic myoid cells: 237.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024513, HPA024522, HPA065849" Approved Enhanced Endosomes NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 39: Astrocytes - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 22 Endosomes "HPA024513: , HPA024522: , HPA065849: " "unprognostic (2.32e-2)" "unprognostic (1.35e-2)" "unprognostic (2.25e-1)" "unprognostic (1.45e-1)" "unprognostic (7.92e-2)" "unprognostic (2.30e-1)" "unprognostic (9.46e-2)" "unprognostic (3.68e-1)" "unprognostic (2.51e-2)" "unprognostic (2.49e-3)" "potential prognostic favorable (7.48e-4)" "unprognostic (1.71e-2)" "unprognostic (5.58e-3)" "unprognostic (1.15e-1)" "unprognostic (6.21e-2)" "unprognostic (1.14e-1)" "unprognostic (5.46e-3)" "unprognostic (9.21e-2)" "unprognostic (1.70e-1)" "unprognostic (3.08e-2)" "unprognostic (3.35e-1)" "unprognostic (5.14e-2)" "unprognostic (7.21e-3)" "unprognostic (5.21e-2)" "unprognostic (1.07e-1)" "unprognostic (1.50e-3)" "unprognostic (5.50e-2)" "unprognostic (1.75e-1)" "unprognostic (1.37e-1)" "unprognostic (9.93e-2)" "unprognostic (1.27e-1)" ANKH "ANK, CCAL2, CMDJ, CPPDD, HANK, SLC62A1" ENSG00000154122 "ANKH inorganic pyrophosphate transport regulator" Q9HCJ1 5 14704800-14871778 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 1154.9;Kupffer cells: 505.3;Lactotrophs: 614.0;Myonuclei: 485.8;Oocytes: 603.3;Prostatic glandular cells: 534.0;Somatotrophs: 847.1;Thyrotrophs: 669.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Prostate - Prostate glandular cells, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068104 Uncertain Cytosol NA NA "Cluster 11: T-cells - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 37: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 5 Cytosol "HPA068104: " "unprognostic (6.10e-2)" "unprognostic (2.41e-1)" "unprognostic (2.44e-1)" "unprognostic (2.18e-1)" "unprognostic (3.60e-1)" "unprognostic (1.08e-1)" "potential prognostic unfavorable (1.45e-4)" "unprognostic (2.27e-2)" "unprognostic (7.00e-2)" "unprognostic (6.28e-2)" "validated prognostic favorable (3.66e-5)" "validated prognostic favorable (5.92e-4)" "unprognostic (1.07e-1)" "unprognostic (4.43e-2)" "unprognostic (1.76e-2)" "unprognostic (5.33e-2)" "unprognostic (3.23e-2)" "unprognostic (1.56e-1)" "unprognostic (1.36e-2)" "unprognostic (8.84e-2)" "unprognostic (7.99e-3)" "unprognostic (1.96e-2)" "unprognostic (1.45e-2)" "unprognostic (1.20e-1)" "unprognostic (2.59e-1)" "unprognostic (3.42e-2)" "unprognostic (1.56e-2)" "unprognostic (1.36e-2)" "unprognostic (2.68e-1)" "unprognostic (6.08e-2)" "unprognostic (1.52e-1)" ANKHD1 "FLJ10042, FLJ11979, FLJ14127, FLJ20288, KIAA1085, MASK, MASK1" ENSG00000131503 "Ankyrin repeat and KH domain containing 1" Q8IWZ3 5 140401814-140539856 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Astrocytes: 169.8;Bergmann glia: 164.2;Brain excitatory neurons: 127.1;Brain inhibitory neurons: 108.9;Choroid plexus epithelial cells: 201.3;Ependymal cells: 151.5;Microglia: 209.2;Oligodendrocyte progenitor cells: 141.9;Oligodendrocytes: 189.4;Other brain neurons: 90.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008718 Approved NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 22: Non-specific - Basic cellular functions" 21 "HPA008718: " "unprognostic (1.08e-2)" "unprognostic (8.08e-2)" "unprognostic (2.43e-1)" "unprognostic (2.26e-1)" "unprognostic (1.84e-1)" "unprognostic (1.16e-1)" "unprognostic (2.41e-1)" "unprognostic (1.66e-1)" "unprognostic (6.94e-2)" "potential prognostic unfavorable (4.70e-4)" "potential prognostic favorable (3.47e-6)" "unprognostic (3.08e-3)" "unprognostic (2.86e-2)" "unprognostic (1.29e-2)" "unprognostic (2.08e-2)" "unprognostic (7.76e-2)" "unprognostic (1.48e-1)" "unprognostic (3.53e-1)" "unprognostic (3.18e-3)" "unprognostic (2.09e-1)" "unprognostic (1.03e-1)" "unprognostic (1.27e-1)" "unprognostic (7.93e-3)" "unprognostic (1.73e-1)" "unprognostic (7.96e-3)" "unprognostic (1.47e-1)" "unprognostic (1.39e-1)" "unprognostic (1.54e-1)" "unprognostic (3.75e-2)" "unprognostic (2.00e-2)" "unprognostic (4.29e-1)" ANKHD1-EIF4EBP3 MASK-BP3 ENSG00000254996 "ANKHD1-EIF4EBP3 readthrough" 5 140401908-140549569 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 39.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" HPA008718 Approved NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 24: Neutrophils - Innate immunity signal integration" 1 "HPA008718: " "unprognostic (2.06e-2)" "unprognostic (4.68e-2)" "unprognostic (4.06e-2)" "unprognostic (1.91e-2)" "unprognostic (1.78e-1)" "unprognostic (4.68e-2)" "unprognostic (1.45e-1)" "unprognostic (2.23e-1)" "unprognostic (1.45e-2)" "potential prognostic favorable (1.68e-7)" "unprognostic (2.14e-2)" "unprognostic (4.90e-3)" "potential prognostic unfavorable (5.79e-5)" "unprognostic (1.08e-1)" "unprognostic (1.73e-1)" "unprognostic (1.70e-2)" "unprognostic (9.15e-2)" "unprognostic (1.88e-3)" "unprognostic (7.42e-3)" "unprognostic (4.64e-3)" "unprognostic (1.29e-1)" "unprognostic (1.19e-1)" "unprognostic (2.52e-1)" "unprognostic (2.04e-1)" "unprognostic (8.36e-2)" "unprognostic (2.66e-1)" "unprognostic (2.86e-1)" "unprognostic (8.54e-3)" "unprognostic (1.87e-2)" ANKIB1 "DKFZP434A0225, KIAA1386" ENSG00000001629 "Ankyrin repeat and IBR domain containing 1" Q9P2G1 7 92245974-92401383 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 684.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019358, HPA021780" Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 80: Oligodendrocytes - Myelination" 2 "Plasma membrane, Cytosol" "HPA019358: , HPA021780: " "unprognostic (1.64e-2)" "unprognostic (2.94e-2)" "unprognostic (2.34e-1)" "unprognostic (1.69e-3)" "unprognostic (4.13e-1)" "unprognostic (1.86e-1)" "unprognostic (4.37e-1)" "unprognostic (1.02e-1)" "unprognostic (1.78e-1)" "potential prognostic unfavorable (2.96e-6)" "potential prognostic favorable (8.50e-6)" "unprognostic (1.71e-1)" "unprognostic (3.76e-2)" "potential prognostic unfavorable (1.23e-4)" "unprognostic (5.01e-2)" "unprognostic (2.62e-2)" "unprognostic (2.58e-2)" "unprognostic (4.10e-2)" "unprognostic (3.34e-1)" "unprognostic (5.97e-2)" "unprognostic (2.70e-3)" "unprognostic (2.89e-3)" "potential prognostic unfavorable (2.04e-4)" "unprognostic (3.85e-2)" "unprognostic (3.23e-3)" "unprognostic (4.17e-2)" "unprognostic (1.01e-1)" "unprognostic (5.62e-3)" "unprognostic (3.10e-1)" "unprognostic (5.62e-2)" "unprognostic (9.61e-2)" ANKK1 X-kinase ENSG00000170209 "Ankyrin repeat and kinase domain containing 1" Q8NFD2 11 113387779-113400416 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "pituitary gland: 2.9;skin 1: 3.3" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 6.3;Ependymal cells: 11.9;Lactotrophs: 10.9;Respiratory ciliated cells: 11.2;Retinal bipolar cells: 7.2;Retinal horizontal cells: 34.1;Somatotrophs: 8.8;Thyrotrophs: 8.1" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 6.5;ependymal cell: 12.2" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells" "Not detected" "Not detected" HPA012813 Uncertain NA NA "Cluster 2: Non-specific - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 13 "HPA012813: " "unprognostic (1.88e-1)" "unprognostic (3.22e-1)" ANKLE1 "ANKRD41, FLJ39369, LEMD6" ENSG00000160117 "Ankyrin repeat and LEM domain containing 1" Q8NAG6 19 17281645-17287646 "Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "bone marrow: 23.4" "Cell type enhanced" "Detected in some" "Erythrocyte progenitors: 35.1;Erythrocytes: 13.7;Megakaryocyte progenitors: 11.5;Megakaryocyte-Erythroid progenitors: 14.9;Megakaryocytes: 12.4;Monocyte progenitors: 6.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Leukemia: 25.7;lymphoma: 28.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA026789, HPA073498" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 15: Bone marrow - Innate immune response" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 47: Leukemia - Hemostasis" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" "Nucleoplasm, Cytosol" "HPA026789: , HPA073498: " "unprognostic (1.32e-1)" "unprognostic (1.06e-1)" "unprognostic (8.87e-3)" "unprognostic (6.21e-2)" "unprognostic (9.59e-2)" "unprognostic (6.51e-2)" "unprognostic (5.47e-2)" "unprognostic (2.85e-3)" "unprognostic (4.42e-2)" "unprognostic (1.01e-1)" "unprognostic (9.56e-2)" "unprognostic (1.06e-1)" "unprognostic (2.34e-3)" "unprognostic (1.39e-3)" "unprognostic (2.71e-1)" "unprognostic (1.98e-1)" "unprognostic (1.06e-2)" "unprognostic (4.78e-2)" "unprognostic (6.19e-2)" "unprognostic (1.44e-1)" "unprognostic (2.50e-2)" ANKLE2 "KIAA0692, Lem4, LEMD7" ENSG00000176915 "Ankyrin repeat and LEM domain containing 2" Q86XL3 12 132725503-132761832 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Mitosis" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 344.9;Urothelial cells: 216.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003602, HPA074838" Uncertain Uncertain "Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 51: Secretory epithelial cells - Mixed function" 33 "Plasma membrane" "Endoplasmic reticulum" "HPA003602: , HPA074838: " "unprognostic (9.63e-2)" "unprognostic (3.49e-1)" "unprognostic (1.55e-1)" "unprognostic (1.11e-3)" "unprognostic (1.49e-1)" "unprognostic (1.89e-2)" "unprognostic (7.37e-2)" "unprognostic (5.59e-2)" "unprognostic (1.72e-1)" "unprognostic (1.08e-2)" "unprognostic (5.19e-2)" "unprognostic (3.62e-3)" "unprognostic (4.36e-1)" "potential prognostic unfavorable (5.27e-5)" "unprognostic (2.71e-3)" "unprognostic (3.50e-2)" "unprognostic (4.82e-2)" "unprognostic (1.16e-1)" "unprognostic (4.81e-2)" "unprognostic (6.68e-2)" "unprognostic (4.48e-1)" "unprognostic (9.26e-2)" "potential prognostic unfavorable (1.08e-5)" "unprognostic (3.77e-2)" "unprognostic (4.89e-2)" "unprognostic (1.45e-2)" "unprognostic (1.45e-1)" "unprognostic (6.32e-2)" "unprognostic (1.72e-1)" "unprognostic (6.30e-2)" "unprognostic (1.76e-1)" ANKMY1 "FLJ20499, ZMYND13" ENSG00000144504 "Ankyrin repeat and MYND domain containing 1" Q9P2S6 2 240479422-240569209 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 30.6" "Cell type enhanced" "Detected in many" "Early spermatids: 296.1;Endometrial ciliated cells: 184.4;Ependymal cells: 295.7;Late primary spermatocytes: 169.5;Late spermatids: 350.9;Respiratory ciliated cells: 332.1" "Cell type enhanced" "Detected in all" "ependymal cell: 284.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA026620, HPA048869" Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 18: Non-specific - Translation" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 34: Ciliated cells - Cilia assembly & function" "Nucleoplasm, Nuclear bodies" Cytosol "HPA026620: , HPA048869: " "unprognostic (2.74e-2)" "unprognostic (1.14e-1)" "unprognostic (2.25e-3)" "unprognostic (1.65e-1)" "unprognostic (1.30e-2)" "unprognostic (9.51e-2)" "unprognostic (4.33e-2)" "unprognostic (9.86e-2)" "unprognostic (3.46e-3)" "unprognostic (1.09e-1)" "unprognostic (2.43e-1)" "unprognostic (1.36e-1)" "unprognostic (2.89e-2)" "unprognostic (3.88e-3)" "unprognostic (8.30e-2)" "unprognostic (7.77e-2)" "unprognostic (3.28e-2)" "unprognostic (1.37e-1)" "unprognostic (2.10e-1)" "unprognostic (7.59e-3)" "unprognostic (2.85e-3)" "unprognostic (1.48e-1)" "unprognostic (8.56e-2)" "unprognostic (4.01e-1)" "unprognostic (2.40e-2)" "unprognostic (1.80e-1)" "unprognostic (5.72e-3)" "unprognostic (3.76e-1)" "unprognostic (2.91e-1)" "unprognostic (1.15e-2)" "unprognostic (4.06e-2)" ANKMY2 "DKFZP564O043, ZMYND20" ENSG00000106524 "Ankyrin repeat and MYND domain containing 2" Q8IV38 7 16599779-16645817 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067100 Approved Nucleoplasm,Cytosol NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 53: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 35: Neurons - Synaptic function & neurogenesis" 12 Cytosol Nucleoplasm "HPA067100: " "unprognostic (1.08e-1)" "unprognostic (1.20e-1)" "unprognostic (5.26e-2)" "unprognostic (2.55e-1)" "unprognostic (3.07e-2)" "unprognostic (1.82e-1)" "unprognostic (1.89e-3)" "unprognostic (9.56e-3)" "unprognostic (2.44e-1)" "unprognostic (1.19e-3)" "potential prognostic favorable (4.80e-6)" "unprognostic (7.71e-3)" "unprognostic (1.51e-2)" "unprognostic (6.09e-3)" "unprognostic (1.82e-2)" "unprognostic (1.05e-1)" "unprognostic (7.31e-2)" "unprognostic (3.53e-3)" "unprognostic (1.36e-1)" "unprognostic (1.29e-1)" "unprognostic (1.57e-2)" "unprognostic (1.95e-1)" "unprognostic (2.50e-1)" "unprognostic (5.48e-2)" "unprognostic (1.49e-1)" "unprognostic (1.79e-3)" "unprognostic (3.94e-2)" "unprognostic (3.46e-2)" "unprognostic (1.69e-2)" "unprognostic (1.23e-1)" "unprognostic (4.75e-1)" ANKRA2 ENSG00000164331 "Ankyrin repeat family A member 2" Q9H9E1 5 73552190-73565667 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 126.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003968, HPA065263" Approved Supported "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 3: Rhabdoid - Membrane components" "Cluster 18: Adrenal cortex cells - Steroidogensis" 17 "Plasma membrane" "Nucleoplasm, Cell Junctions" "HPA003968: , HPA065263: " "unprognostic (3.13e-1)" "unprognostic (3.49e-1)" "unprognostic (4.92e-2)" "unprognostic (1.04e-1)" "unprognostic (2.50e-2)" "unprognostic (2.53e-1)" "unprognostic (6.97e-3)" "unprognostic (1.65e-1)" "unprognostic (1.04e-1)" "unprognostic (1.64e-1)" "unprognostic (1.20e-3)" "unprognostic (2.33e-2)" "unprognostic (6.40e-2)" "unprognostic (1.20e-1)" "unprognostic (2.81e-1)" "unprognostic (3.91e-2)" "unprognostic (1.84e-2)" "unprognostic (6.81e-2)" "unprognostic (3.80e-2)" "unprognostic (5.07e-2)" "unprognostic (3.62e-1)" "unprognostic (5.63e-2)" "unprognostic (1.77e-2)" "unprognostic (1.30e-1)" "unprognostic (1.29e-3)" "unprognostic (2.23e-1)" "unprognostic (4.86e-1)" "unprognostic (1.79e-1)" "unprognostic (3.43e-1)" "unprognostic (1.47e-2)" "unprognostic (1.81e-1)" ANKRD1 "ALRP, C-193, CARP, CVARP, MCARP" ENSG00000148677 "Ankyrin repeat domain 1" Q15327 10 90912096-90921087 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "heart muscle: 6125.5" "Group enriched" "Detected in some" 4 "Alveolar cells type 1: 1510.9;Thymic myoid cells: 659.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 12.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 432.3" "Pancreas - Ductal cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA038736 Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center" NA Yes "Cluster 35: Non-specific - Mixed function" "Cluster 12: Non-specific - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 7 "Nucleoli fibrillar center" Nucleoplasm "HPA038736: " "potential prognostic unfavorable (9.18e-4)" "unprognostic (1.60e-1)" "unprognostic (1.03e-2)" "unprognostic (3.49e-2)" "potential prognostic unfavorable (2.18e-4)" "unprognostic (5.17e-3)" "unprognostic (9.52e-2)" "unprognostic (2.04e-2)" "unprognostic (3.45e-2)" "unprognostic (1.58e-2)" "unprognostic (1.52e-1)" "unprognostic (8.07e-2)" "unprognostic (3.88e-3)" "unprognostic (5.17e-2)" "unprognostic (1.94e-2)" "potential prognostic unfavorable (1.29e-5)" "unprognostic (2.13e-1)" "unprognostic (1.15e-1)" "unprognostic (1.77e-1)" "unprognostic (2.01e-1)" ANKRD10 FLJ20093 ENSG00000088448 "Ankyrin repeat domain 10" Q9NXR5 13 110878540-110915069 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034211, HPA038878, HPA038879" Uncertain Supported Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 24: Non-specific - Transcription" "Cluster 30: White matter - Myelination" "Cluster 19: Non-specific - Unknown function" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 5 Nucleoplasm "CAB034211: , HPA038878: , HPA038879: " "unprognostic (2.14e-3)" "unprognostic (4.90e-2)" "unprognostic (4.14e-3)" "unprognostic (2.82e-1)" "unprognostic (3.45e-2)" "unprognostic (5.66e-2)" "potential prognostic favorable (9.12e-4)" "unprognostic (1.72e-3)" "unprognostic (8.52e-2)" "unprognostic (2.86e-3)" "potential prognostic unfavorable (2.24e-4)" "unprognostic (7.60e-2)" "unprognostic (3.04e-2)" "potential prognostic unfavorable (3.26e-4)" "unprognostic (2.06e-1)" "unprognostic (1.27e-1)" "unprognostic (2.12e-1)" "unprognostic (4.42e-2)" "unprognostic (1.70e-1)" "unprognostic (1.85e-1)" "unprognostic (6.13e-2)" "unprognostic (9.22e-2)" "unprognostic (5.08e-2)" "unprognostic (9.63e-2)" "unprognostic (1.25e-1)" "unprognostic (1.59e-2)" "unprognostic (7.33e-2)" "unprognostic (3.88e-1)" "unprognostic (1.67e-1)" "unprognostic (3.23e-2)" "unprognostic (7.33e-2)" ANKRD11 "ANCO-1, ANCO1, LZ16, T13" ENSG00000167522 "Ankyrin repeat domain containing 11" Q6UB99 16 89267630-89490561 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 1162.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019288, HPA041593, HPA049470" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 41: Basophils - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 19 Nucleoplasm Cytosol "CAB019288: , HPA041593: , HPA049470: " "unprognostic (2.87e-1)" "unprognostic (1.61e-1)" "unprognostic (3.23e-2)" "unprognostic (1.61e-1)" "unprognostic (3.84e-2)" "unprognostic (6.86e-2)" "unprognostic (3.24e-1)" "unprognostic (8.47e-2)" "unprognostic (6.48e-2)" "unprognostic (2.31e-2)" "unprognostic (1.02e-1)" "unprognostic (2.06e-1)" "unprognostic (1.57e-2)" "potential prognostic unfavorable (3.66e-6)" "unprognostic (1.75e-1)" "unprognostic (2.60e-3)" "unprognostic (8.97e-3)" "unprognostic (6.10e-2)" "unprognostic (1.55e-2)" "unprognostic (1.76e-1)" "unprognostic (2.87e-1)" "unprognostic (1.39e-2)" "potential prognostic unfavorable (4.17e-5)" "unprognostic (9.33e-3)" "unprognostic (1.45e-1)" "unprognostic (4.75e-2)" "unprognostic (6.00e-2)" "unprognostic (4.88e-1)" "unprognostic (4.03e-2)" "unprognostic (1.50e-1)" "unprognostic (1.28e-1)" ANKRD12 "ANCO-2, FLJ20053, GAC-1, KIAA0874" ENSG00000101745 "Ankyrin repeat domain 12" Q6UB98 18 9136228-9285985 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040705 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 40: Non-specific - Mixed function" "Cluster 16: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 51: Secretory epithelial cells - Mixed function" 3 Nucleoplasm Cytosol "HPA040705: " "unprognostic (2.81e-2)" "unprognostic (2.68e-1)" "unprognostic (2.08e-1)" "unprognostic (2.03e-3)" "unprognostic (1.43e-1)" "unprognostic (6.25e-2)" "unprognostic (1.46e-1)" "unprognostic (5.05e-3)" "unprognostic (4.24e-2)" "unprognostic (6.83e-3)" "potential prognostic favorable (7.95e-4)" "unprognostic (2.73e-3)" "unprognostic (2.01e-2)" "unprognostic (2.94e-1)" "unprognostic (3.38e-1)" "unprognostic (3.10e-2)" "potential prognostic favorable (2.01e-5)" "unprognostic (1.83e-1)" "unprognostic (1.41e-1)" "unprognostic (1.00e-1)" "potential prognostic unfavorable (1.18e-4)" "unprognostic (5.80e-2)" "unprognostic (3.17e-3)" "unprognostic (5.19e-2)" "unprognostic (2.52e-2)" "unprognostic (2.36e-1)" "unprognostic (8.28e-2)" "unprognostic (1.21e-1)" "unprognostic (1.67e-1)" "unprognostic (8.33e-2)" "unprognostic (2.71e-1)" ANKRD13A "ANKRD13, NY-REN-25" ENSG00000076513 "Ankyrin repeat domain 13A" Q8IZ07 12 109999186-110039763 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 258.2;Neutrophil progenitors: 229.4;Neutrophils: 571.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells, Spleen - B-cells (Spleen), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039488, HPA043218" Enhanced Supported "Vesicles,Plasma membrane,Primary cilium,Primary cilium tip,Primary cilium transition zone" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 11: White matter - Signal transduction" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 41 "Plasma membrane" "Vesicles, Primary cilium, Primary cilium tip, Primary cilium transition zone" "HPA039488: , HPA043218: " "unprognostic (1.48e-1)" "unprognostic (9.99e-3)" "unprognostic (8.13e-2)" "unprognostic (1.11e-1)" "unprognostic (5.70e-2)" "unprognostic (3.02e-1)" "unprognostic (1.89e-1)" "unprognostic (1.49e-3)" "unprognostic (6.64e-3)" "potential prognostic unfavorable (6.22e-4)" "potential prognostic favorable (4.43e-8)" "unprognostic (3.40e-2)" "unprognostic (2.03e-2)" "unprognostic (2.43e-1)" "unprognostic (9.95e-2)" "unprognostic (8.33e-3)" "unprognostic (7.25e-2)" "unprognostic (1.35e-3)" "unprognostic (2.85e-1)" "unprognostic (6.02e-3)" "unprognostic (1.47e-2)" "unprognostic (5.75e-2)" "unprognostic (1.71e-1)" "unprognostic (3.76e-2)" "unprognostic (1.24e-1)" "unprognostic (4.99e-2)" "unprognostic (3.30e-1)" "unprognostic (1.99e-1)" "unprognostic (4.98e-1)" "unprognostic (1.99e-1)" "unprognostic (1.88e-3)" ANKRD13B FLJ25555 ENSG00000198720 "Ankyrin repeat domain 13B" Q86YJ7 17 29589769-29614761 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 44.3" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 1.1;Late spermatids: 3.0" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Colon - Enteric glia cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051886, HPA063748" Uncertain Uncertain "Vesicles,Plasma membrane" NA NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 34: Non-specific - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 2 Vesicles "Plasma membrane" "HPA051886: , HPA063748: " "unprognostic (3.42e-2)" "unprognostic (1.55e-1)" "unprognostic (3.64e-2)" "unprognostic (1.52e-1)" "unprognostic (6.42e-2)" "unprognostic (2.80e-1)" "unprognostic (1.73e-1)" "unprognostic (1.26e-3)" "unprognostic (1.49e-1)" "unprognostic (4.03e-3)" "unprognostic (1.26e-1)" "unprognostic (2.38e-2)" "unprognostic (5.86e-3)" "unprognostic (1.47e-1)" "unprognostic (7.60e-2)" "unprognostic (2.78e-1)" "unprognostic (6.70e-3)" "unprognostic (2.86e-2)" "unprognostic (4.61e-2)" "unprognostic (1.06e-1)" "unprognostic (7.33e-2)" "unprognostic (4.26e-2)" "unprognostic (4.18e-3)" "potential prognostic favorable (5.88e-4)" "unprognostic (1.42e-1)" "unprognostic (7.64e-2)" "unprognostic (4.32e-2)" "unprognostic (1.12e-3)" "unprognostic (1.67e-1)" ANKRD13C "dJ677H15.3, DKFZP566D1346" ENSG00000118454 "Ankyrin repeat domain 13C" Q8N6S4 1 70258999-70354734 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 9: T-cells - Adaptive immunity: Regulation" 3 "unprognostic (2.21e-2)" "unprognostic (1.18e-1)" "unprognostic (1.91e-1)" "unprognostic (1.03e-1)" "unprognostic (1.64e-2)" "unprognostic (1.86e-1)" "unprognostic (1.33e-2)" "unprognostic (2.07e-2)" "unprognostic (1.27e-2)" "unprognostic (2.21e-3)" "potential prognostic favorable (1.02e-5)" "unprognostic (5.46e-3)" "unprognostic (8.14e-2)" "unprognostic (1.62e-3)" "unprognostic (8.99e-2)" "unprognostic (1.19e-2)" "unprognostic (4.65e-2)" "unprognostic (2.53e-1)" "unprognostic (1.47e-2)" "unprognostic (1.11e-1)" "unprognostic (1.33e-2)" "unprognostic (2.72e-2)" "unprognostic (1.89e-2)" "unprognostic (2.45e-2)" "unprognostic (1.55e-2)" "unprognostic (2.25e-1)" "unprognostic (1.64e-1)" "unprognostic (7.15e-2)" "unprognostic (2.01e-1)" "unprognostic (1.11e-1)" "unprognostic (4.15e-2)" ANKRD13D ENSG00000172932 "Ankyrin repeat domain 13D" Q6ZTN6 11 67289300-67302485 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Neutrophil progenitors: 243.2;Neutrophils: 291.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039950 Approved NA No "Cluster 5: Non-specific - Cell proliferation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 24: Non-specific - Unknown function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 5 "HPA039950: " "unprognostic (2.41e-2)" "unprognostic (9.69e-2)" "potential prognostic favorable (3.69e-4)" "unprognostic (1.22e-1)" "unprognostic (2.12e-1)" "unprognostic (2.47e-1)" "unprognostic (2.10e-2)" "unprognostic (3.82e-2)" "unprognostic (4.54e-2)" "unprognostic (1.95e-1)" "unprognostic (1.32e-1)" "unprognostic (6.60e-2)" "unprognostic (2.18e-1)" "potential prognostic unfavorable (5.99e-4)" "unprognostic (2.04e-1)" "unprognostic (2.14e-1)" "unprognostic (4.17e-2)" "unprognostic (3.34e-1)" "unprognostic (4.56e-2)" "unprognostic (4.36e-3)" "unprognostic (6.23e-3)" "unprognostic (4.31e-2)" "potential prognostic unfavorable (2.30e-4)" "unprognostic (1.64e-2)" "unprognostic (4.00e-3)" "unprognostic (1.98e-1)" "unprognostic (2.06e-1)" "unprognostic (1.09e-1)" "unprognostic (1.26e-1)" "unprognostic (4.29e-3)" "unprognostic (3.67e-1)" ANKRD16 DKFZP434N1511 ENSG00000134461 "Ankyrin repeat domain 16" Q6P6B7 10 5861616-5889906 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 59.9;Retinal horizontal cells: 56.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037920, HPA037921" Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 21: Testis - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 7: Non-specific - Transcription" 2 "Endoplasmic reticulum" "HPA037920: , HPA037921: " "unprognostic (1.07e-1)" "unprognostic (5.71e-2)" "unprognostic (4.78e-2)" "unprognostic (1.71e-1)" "unprognostic (4.73e-3)" "unprognostic (4.74e-2)" "unprognostic (1.73e-1)" "potential prognostic favorable (6.32e-5)" "unprognostic (9.47e-3)" "unprognostic (4.90e-2)" "unprognostic (1.82e-1)" "unprognostic (3.53e-2)" "unprognostic (4.26e-2)" "unprognostic (1.60e-3)" "unprognostic (1.38e-2)" "unprognostic (4.55e-1)" "unprognostic (1.10e-2)" "unprognostic (2.01e-1)" "unprognostic (1.47e-2)" "unprognostic (1.40e-1)" "unprognostic (8.00e-2)" "unprognostic (1.12e-3)" "unprognostic (1.27e-1)" "unprognostic (3.37e-2)" "unprognostic (1.12e-1)" "unprognostic (3.44e-2)" "unprognostic (1.77e-1)" "unprognostic (4.27e-2)" "unprognostic (4.32e-2)" "unprognostic (2.32e-1)" "unprognostic (8.28e-2)" ANKRD17 "FLJ22206, GTAR, KIAA0697, MASK2, NY-BR-16" ENSG00000132466 "Ankyrin repeat domain 17" O75179 4 73073376-73258798 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Immunity, Innate immunity" RNA-binding "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045024, HPA063731" Approved Supported "Nucleoplasm,Nuclear membrane" No No "Cluster 30: Non-specific - DNA binding" "Cluster 61: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 17: Non-specific - RNA processing" 27 Nucleoplasm "Nuclear membrane" "HPA045024: , HPA063731: " "unprognostic (1.23e-1)" "unprognostic (5.19e-2)" "unprognostic (4.79e-1)" "unprognostic (1.73e-3)" "unprognostic (5.29e-2)" "unprognostic (1.89e-1)" "unprognostic (2.56e-2)" "unprognostic (8.83e-2)" "unprognostic (2.45e-1)" "potential prognostic unfavorable (1.69e-4)" "validated prognostic favorable (1.29e-5)" "validated prognostic favorable (8.03e-4)" "unprognostic (3.33e-1)" "unprognostic (2.51e-3)" "unprognostic (1.18e-1)" "unprognostic (4.24e-2)" "unprognostic (7.03e-2)" "unprognostic (5.14e-2)" "unprognostic (8.36e-2)" "unprognostic (1.10e-1)" "unprognostic (2.92e-1)" "unprognostic (2.01e-2)" "unprognostic (2.41e-2)" "unprognostic (8.49e-2)" "unprognostic (6.50e-2)" "unprognostic (2.22e-2)" "unprognostic (9.49e-2)" "unprognostic (1.34e-1)" "unprognostic (2.12e-1)" "unprognostic (1.98e-2)" "unprognostic (2.43e-1)" ANKRD18A "FLJ35740, KIAA2015" ENSG00000180071 "Ankyrin repeat domain 18A" Q8IVF6 9 38540567-38620596 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 17.6;testis: 7.2" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 79.0;Endometrial ciliated cells: 90.7;Epididymal efferent duct ciliated cells: 109.5;Gonadotrophs: 131.8;Neutrophil progenitors: 212.3;Rod photoreceptor cells: 95.8;Sertoli cells: 475.4" "Cell type enhanced" "Detected in many" "medium spiny neuron: 103.9;oligodendrocyte: 136.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Skin - Keratinocyte (other)" "HPA046346, HPA046695, HPA049923, HPA051288" Uncertain NA NA "Cluster 44: Bone marrow - Nuclear processes" "Cluster 30: White matter - Myelination" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 37: Neutrophil progenitors - Granulopoiesis" "HPA046346: , HPA046695: , HPA049923: , HPA051288: " "unprognostic (1.92e-1)" "unprognostic (2.40e-3)" "unprognostic (3.66e-3)" "unprognostic (5.41e-3)" "unprognostic (5.88e-3)" "unprognostic (7.30e-2)" "unprognostic (2.15e-3)" "unprognostic (8.37e-2)" "unprognostic (1.58e-2)" ANKRD18B bA255A11.3 ENSG00000230453 "Ankyrin repeat domain 18B" A2A2Z9 9 33524251-33608848 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 7.7;testis: 4.1" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 27.6;Early primary spermatocytes: 23.5;Early spermatids: 60.3;Endometrial ciliated cells: 25.4;Epididymal efferent duct ciliated cells: 81.8;Late primary spermatocytes: 23.7;Müller glia: 37.9;Prostatic hillock cells: 24.9;Retinal pigment epithelial cells: 25.6;Sertoli cells: 131.0;Urothelial cells: 24.3" "Cell type enhanced" "Detected in many" "lower rhombic lip: 58.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Pituitary gland - Gonadotropes, Skin - Keratinocyte (other)" "HPA046346, HPA046695, HPA049923, HPA051288" Uncertain NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 37: Neurons - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" "HPA046346: , HPA046695: , HPA049923: , HPA051288: " "unprognostic (1.02e-2)" "unprognostic (1.21e-2)" "unprognostic (3.84e-2)" "unprognostic (1.96e-2)" "unprognostic (4.33e-2)" "unprognostic (5.43e-2)" "unprognostic (1.00e-2)" "unprognostic (8.64e-3)" "unprognostic (9.25e-2)" "unprognostic (4.80e-2)" "unprognostic (2.28e-1)" "unprognostic (1.90e-1)" ANKRD2 ARPP ENSG00000165887 "Ankyrin repeat domain 2" Q9GZV1 10 97572499-97583884 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 44 "heart muscle: 495.5;skeletal muscle: 1141.9;tongue: 769.1" "Group enriched" "Detected in some" 10 "Cardiomyocytes: 62.4;Myonuclei: 248.4;Thymic myoid cells: 142.8" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Kidney Renal Papillary Cell Carcinoma (TCGA): 22.1;Testicular Germ Cell Tumor (TCGA): 9.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Uterine cancer: 16.6" "Heart muscle - Cardiomyocytes, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA040842, HPA040884" Enhanced Enhanced Vesicles NA NA 7100 "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 55: Myocytes - Oxidative muscle function" 6 Vesicles "HPA040842: , HPA040884: " "unprognostic (7.94e-2)" "unprognostic (1.31e-2)" "unprognostic (2.33e-3)" "unprognostic (3.78e-1)" "unprognostic (4.00e-2)" "unprognostic (3.96e-2)" "unprognostic (4.45e-2)" "unprognostic (4.18e-2)" "unprognostic (2.80e-1)" "unprognostic (1.38e-1)" "unprognostic (1.57e-1)" "unprognostic (5.54e-2)" ANKRD20A1 "ANKRD20A, DKFZp434A171" ENSG00000260691 "Ankyrin repeat domain 20 family member A1" Q5TYW2 9 67832765-67920552 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "testis: 3.9" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 13.8;Early primary spermatocytes: 24.6;Oligodendrocyte progenitor cells: 11.8;Undifferentiated spermatogonia: 62.4" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "HPA043239, HPA046346, HPA046695, HPA047112, HPA047167, HPA047766, HPA049923, HPA051288, HPA051753, HPA054389" Uncertain Approved Nucleoplasm NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 106: Spermatogonia - Spermatogonial differentiation" Nucleoplasm "HPA043239: , HPA046346: , HPA046695: , HPA047112: , HPA047167: , HPA047766: , HPA049923: , HPA051288: , HPA051753: , HPA054389: " ANKRD22 MGC22805 ENSG00000152766 "Ankyrin repeat domain 22" Q5VYY1 10 88819896-88851844 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 18.0;skin 1: 23.5;stomach 1: 28.4" "Cell type enhanced" "Detected in many" "Colonocytes: 98.3;Esophageal apical cells: 296.6;Esophageal suprabasal cells: 171.6;Foveolar cells: 83.0;Gastric chief cells: 193.3;Mucous neck cells: 234.4;Neutrophil progenitors: 137.0;Neutrophils: 155.1;Parietal cells: 171.5;Renal collecting duct intercalated cells: 69.7;Suprabasal keratinocytes: 196.8;Urothelial cells: 95.5" "Cell type enriched" "Detected in some" 4 "central nervous system macrophage: 6.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 6.4" "Group enriched" "Detected in many" 14 "granulocytes: 6.4;monocytes: 3.1" "Cancer enhanced" "Detected in many" "Bile duct cancer: 13.4;Gallbladder cancer: 14.7" "Skin - Keratinocyte (other)" "Not detected" "Not detected" "Not detected" "Not detected" HPA012922 Approved Approved Nucleoplasm NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 58: Skin - Keratinization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 85: Squamous epithelial cells - Keratinization" 5 Nucleoplasm "HPA012922: " "unprognostic (1.57e-1)" "unprognostic (4.22e-1)" "unprognostic (1.77e-1)" "unprognostic (1.23e-2)" "unprognostic (6.33e-2)" "unprognostic (2.54e-2)" "unprognostic (2.38e-1)" "unprognostic (5.29e-3)" "unprognostic (3.73e-2)" "unprognostic (7.68e-3)" "unprognostic (1.82e-2)" "unprognostic (5.32e-2)" "unprognostic (3.40e-2)" "unprognostic (1.44e-2)" "unprognostic (3.74e-2)" "unprognostic (1.05e-1)" "unprognostic (8.93e-2)" "unprognostic (1.01e-1)" "unprognostic (4.67e-2)" "unprognostic (5.76e-2)" "unprognostic (7.66e-3)" "unprognostic (1.47e-3)" "unprognostic (5.23e-2)" "unprognostic (4.40e-3)" "unprognostic (2.54e-2)" "unprognostic (2.27e-2)" "unprognostic (5.15e-1)" "unprognostic (8.52e-3)" "unprognostic (4.25e-2)" "unprognostic (1.44e-3)" "unprognostic (2.92e-3)" ANKRD23 "DARP, FLJ32449, MARP3" ENSG00000163126 "Ankyrin repeat domain 23" Q86SG2 2 96824526-96857934 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 38 "skeletal muscle: 1347.5;tongue: 418.8" "Group enriched" "Detected in many" 4 "Myonuclei: 472.9;Thymic myoid cells: 174.0" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in some" 4 "Head and Neck Squamous Cell Carcinoma (TCGA): 7.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Colon - Enteric glia cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA036201 Approved Approved "Nucleoplasm,Actin filaments,Cytosol" NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 6: Non-specific - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 18 "Nucleoplasm, Cytosol" "Actin filaments" "HPA036201: " "unprognostic (7.20e-3)" "unprognostic (6.17e-3)" "unprognostic (6.78e-2)" "unprognostic (4.47e-2)" "unprognostic (3.30e-1)" "unprognostic (2.33e-2)" "unprognostic (5.50e-2)" ANKRD24 KIAA1981 ENSG00000089847 "Ankyrin repeat domain 24" Q8TF21 19 4182689-4224814 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.9;testis: 13.7" "Cell type enhanced" "Detected in many" "Astrocytes: 17.5;Brain excitatory neurons: 19.6;Cone photoreceptor cells: 18.6;Extravillous trophoblasts: 33.7;Retinal ganglion cells: 42.5" "Cell type enhanced" "Detected in all" "upper-layer intratelencephalic: 79.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 5.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041534, HPA048498" Uncertain Uncertain Microtubules,Cytosol NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 35: Neurons - Synaptic function & neurogenesis" 1 "Microtubules, Cytosol" "HPA041534: , HPA048498: " "unprognostic (2.31e-1)" "unprognostic (1.24e-2)" "unprognostic (1.59e-1)" "unprognostic (1.26e-1)" "unprognostic (2.00e-2)" "unprognostic (7.79e-2)" "validated prognostic favorable (1.36e-5)" "validated prognostic favorable (4.64e-4)" "unprognostic (1.49e-1)" "unprognostic (2.39e-1)" "unprognostic (3.58e-3)" ANKRD26 "KIAA1074, THC2" ENSG00000107890 "Ankyrin repeat domain containing 26" Q9UPS8 10 26973793-27100494 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ependymal cells: 487.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "HPA040654, HPA041460" Approved Approved "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 34: Ciliated cells - Cilia assembly & function" 11 "Golgi apparatus" "Vesicles, Cytosol" "HPA040654: , HPA041460: " "unprognostic (5.34e-2)" "unprognostic (2.24e-1)" "unprognostic (2.49e-2)" "unprognostic (2.24e-2)" "unprognostic (1.36e-1)" "unprognostic (1.07e-1)" "unprognostic (4.86e-1)" "potential prognostic favorable (2.44e-5)" "unprognostic (2.31e-1)" "unprognostic (2.96e-3)" "unprognostic (3.55e-1)" "unprognostic (3.77e-2)" "unprognostic (6.47e-2)" "potential prognostic unfavorable (2.59e-6)" "unprognostic (1.71e-1)" "unprognostic (8.91e-2)" "unprognostic (1.59e-1)" "unprognostic (4.21e-2)" "unprognostic (8.94e-3)" "unprognostic (7.88e-2)" "potential prognostic unfavorable (9.73e-5)" "unprognostic (1.33e-2)" "unprognostic (1.18e-3)" "unprognostic (8.63e-2)" "unprognostic (1.98e-2)" "unprognostic (6.44e-2)" "unprognostic (1.61e-1)" "unprognostic (9.78e-2)" "unprognostic (2.59e-2)" "unprognostic (5.07e-2)" "unprognostic (7.26e-2)" ANKRD27 "DKFZp434L0718, FLJ00040, VARP" ENSG00000105186 "Ankyrin repeat domain 27" Q96NW4 19 32597006-32676597 "Predicted intracellular proteins" "Protein transport, Transport" "GTPase activation, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 167.6;Cone photoreceptor cells: 192.5;Megakaryocyte-Erythroid progenitors: 142.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042769 Approved Supported Vesicles,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 39: Testis - Nuclear processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 16 Vesicles Cytosol "HPA042769: " "unprognostic (4.92e-2)" "unprognostic (4.61e-2)" "unprognostic (4.20e-1)" "unprognostic (7.56e-2)" "unprognostic (1.90e-1)" "unprognostic (2.84e-1)" "unprognostic (1.53e-1)" "unprognostic (1.15e-2)" "unprognostic (1.09e-1)" "unprognostic (2.33e-1)" "potential prognostic favorable (1.50e-5)" "unprognostic (1.09e-1)" "unprognostic (4.40e-2)" "validated prognostic unfavorable (2.74e-5)" "validated prognostic unfavorable (8.10e-4)" "unprognostic (1.77e-1)" "unprognostic (1.77e-1)" "unprognostic (1.34e-1)" "unprognostic (4.78e-1)" "unprognostic (1.96e-3)" "unprognostic (1.14e-1)" "unprognostic (2.11e-2)" "potential prognostic unfavorable (2.97e-4)" "unprognostic (4.16e-2)" "potential prognostic favorable (9.70e-5)" "unprognostic (2.80e-1)" "unprognostic (2.10e-1)" "unprognostic (2.61e-1)" "unprognostic (6.31e-2)" "unprognostic (1.97e-1)" "unprognostic (2.82e-1)" ANKRD28 "CFAP79, FAP79, KIAA0379, PITK, PP6-ARS-A, PPP1R65" ENSG00000206560 "Ankyrin repeat domain 28" O15084 3 15667236-15859771 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hematopoietic stem cells: 1189.8;Innate lymphoid cells: 861.0;Mast cells: 1229.0;Plasma cells: 3063.7;Thymocytes: 903.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 26 "basophil: 17.1" "Lineage enriched" "Detected in single" 26 "granulocytes: 17.1" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 16000 "Cluster 46: Basophils - Proteolysis" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 78: Plasma cells - Antibody production & ER-stress response" 50 "unprognostic (1.63e-1)" "unprognostic (2.35e-1)" "unprognostic (1.03e-1)" "unprognostic (1.92e-1)" "unprognostic (1.89e-1)" "unprognostic (3.06e-2)" "unprognostic (5.10e-2)" "unprognostic (1.47e-1)" "unprognostic (7.44e-2)" "unprognostic (1.31e-2)" "unprognostic (1.65e-2)" "unprognostic (1.71e-1)" "unprognostic (5.12e-2)" "unprognostic (2.18e-1)" "unprognostic (2.05e-1)" "unprognostic (2.32e-1)" "unprognostic (2.71e-2)" "unprognostic (3.08e-1)" "unprognostic (3.21e-1)" "unprognostic (1.01e-1)" "unprognostic (5.46e-2)" "unprognostic (3.12e-3)" "unprognostic (1.53e-2)" "unprognostic (1.45e-1)" "unprognostic (3.10e-3)" "unprognostic (2.94e-3)" "unprognostic (1.29e-1)" "unprognostic (2.41e-1)" "unprognostic (1.45e-1)" "unprognostic (5.71e-3)" "unprognostic (3.55e-2)" ANKRD29 FLJ25053 ENSG00000154065 "Ankyrin repeat domain 29" Q8N6D5 18 23598926-23662911 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Alveolar cells type 1: 490.7" "Cell type enhanced" "Detected in all" "endothelial cell: 207.0" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 24.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Lung - Alveolar cells type 1, Skeletal muscle - Fibroblasts, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041272, HPA049419" Uncertain Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 7 "Nucleoplasm, Nuclear bodies" "HPA041272: , HPA049419: " "unprognostic (1.07e-1)" "unprognostic (2.50e-3)" "unprognostic (1.38e-1)" "unprognostic (9.41e-2)" "unprognostic (2.19e-1)" "unprognostic (1.33e-1)" "validated prognostic unfavorable (7.07e-4)" "validated prognostic unfavorable (6.78e-4)" "potential prognostic favorable (9.74e-5)" "unprognostic (2.26e-1)" "unprognostic (9.57e-2)" "unprognostic (1.79e-1)" "potential prognostic favorable (2.43e-4)" "unprognostic (1.25e-1)" "unprognostic (1.41e-1)" "potential prognostic favorable (9.88e-4)" "unprognostic (1.51e-2)" "unprognostic (2.78e-2)" "unprognostic (4.81e-2)" "unprognostic (1.59e-2)" "unprognostic (7.60e-2)" "unprognostic (1.06e-1)" "unprognostic (2.23e-2)" "unprognostic (3.34e-1)" "unprognostic (1.50e-1)" "unprognostic (6.00e-3)" "unprognostic (1.52e-1)" "unprognostic (1.16e-2)" "unprognostic (1.48e-1)" "unprognostic (2.15e-1)" ANKRD30A NY-BR-1 ENSG00000148513 "Ankyrin repeat domain 30A" Q9BXX3 10 37125598-37232567 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 36 "breast: 62.0" "Cell type enriched" "Detected in some" 8 "Breast hormone-responsive cells: 828.3" "Cell type enhanced" "Detected in some" "splatter: 3.9" "Cancer enriched" "Detected in single" 41 "Breast Invasive Carcinoma (TCGA): 24.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "breast cancer: 16.6;Myeloma: 8.9" "Breast - Breast glandular cells, Testis - Early spermatids, Testis - Spermatocytes" HPA071849 Uncertain Nucleoli NA NA "Cluster 55: Breast - Lactation" "Cluster 27: Breast cancer - Unknown function" "Cluster 38: Secretory epithelial cells - Exocrine secretion" Nucleoli "HPA071849: " "unprognostic (1.57e-1)" "unprognostic (2.49e-2)" ANKRD30B NY-BR-1.1 ENSG00000180777 "Ankyrin repeat domain 30B" Q9BXX2 18 14728272-14854667 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 8.3" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 35.7;Brain inhibitory neurons: 49.5;Breast hormone-responsive cells: 13.3;Early primary spermatocytes: 79.0;Epicardial cells: 15.9;Late primary spermatocytes: 30.3;Medullary thymic epithelial cells: 14.4;Mesothelial cells: 16.7;Other brain neurons: 38.4;Podocytes: 13.9;Undifferentiated spermatogonia: 14.9" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in some" 8 "Breast Invasive Carcinoma (TCGA): 3.7;Skin Cutaneous Melanoma (TCGA): 1.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "breast cancer: 3.9;Sarcoma: 5.0;skin cancer: 1.9;thyroid cancer: 1.4" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Stomach - Chief cells, Testis - Early spermatids" "HPA043287, HPA060455, HPA071849" Uncertain Approved Nucleoplasm,Nucleoli NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 53: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 109: Neurons - Neuronal signaling" Nucleoli Nucleoplasm "HPA043287: , HPA060455: , HPA071849: " "unprognostic (4.91e-2)" "unprognostic (4.79e-2)" "unprognostic (4.85e-2)" ANKRD30BL "ANKRD30BP3, NCRNA00164" ENSG00000163046 "Ankyrin repeat domain 30B like" A7E2S9 2 132147591-132257969 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 28 "testis: 7.4" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 313.9;Brain inhibitory neurons: 417.5;Choroid plexus epithelial cells: 526.0;Ependymal cells: 159.0;Oligodendrocyte progenitor cells: 101.5;Other brain neurons: 379.2;Pituicytes/FSCs: 85.5;Retinal amacrine cells: 158.4" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" HPA076167 Approved "Plasma membrane" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 109: Neurons - Neuronal signaling" "Plasma membrane" "HPA076167: " "unprognostic (2.91e-3)" ANKRD31 FLJ40191 ENSG00000145700 "Ankyrin repeat domain 31" Q8N7Z5 5 75068275-75236911 "Predicted intracellular proteins" "DNA recombination, Meiosis" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "testis: 4.6" "Cell type enriched" "Detected in many" 5 "Early primary spermatocytes: 244.2" "Cell type enhanced" "Detected in all" "ependymal cell: 38.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA038028, HPA057566" Enhanced Approved Nucleoplasm,Nucleoli,Vesicles,Centrosome NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 46: Brainstem - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 3: Early primary spermatocytes - Early meiosis" "Nucleoplasm, Centrosome" "Nucleoli, Vesicles" "HPA038028: , HPA057566: " ANKRD33 "C12orf7, DKFZp686O1689, PANKY" ENSG00000167612 "Ankyrin repeat domain 33" Q7Z3H0 12 51888009-51891727 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "retina: 17.0" "Group enriched" "Detected in some" 7 "Cone photoreceptor cells: 68.3;Rod photoreceptor cells: 89.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA058753 Enhanced NA NA "Cluster 42: Retina - Visual perception" "Cluster 1: Neuronal - Visual perception" "Cluster 79: Photoreceptor cells - Phototransduction" 1 "HPA058753: " ANKRD33B ENSG00000164236 "Ankyrin repeat domain 33B" A6NCL7 5 10564070-10657816 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "retina: 47.3" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 1165.5;Endometrial luminal cells: 351.1;Fallopian secretory cells: 194.7;Neutrophil progenitors: 200.8;Platelets: 241.6;Podocytes: 658.4;Rod photoreceptor cells: 379.9" "Cell type enhanced" "Detected in many" "hippocampal CA4: 292.6;hippocampal dentate gyrus: 247.4" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 13.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Fibroblasts, Kidney - Proximal tubular cells, Pancreas - Ductal cells" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 6 "amygdala: 11.2;basal ganglia: 23.1;cerebral cortex: 27.6;hippocampal formation: 22.9;olfactory bulb: 14.5" HPA056974 Uncertain Approved Mitochondria NA NA "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 51: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 82: Dendritic cells - Antigen presentation" 2 Mitochondria "HPA056974: " "unprognostic (2.29e-1)" "unprognostic (8.90e-2)" "unprognostic (3.15e-1)" "unprognostic (2.03e-1)" "unprognostic (1.53e-1)" "unprognostic (1.78e-1)" "potential prognostic favorable (3.65e-9)" "unprognostic (2.37e-2)" "unprognostic (2.01e-1)" "unprognostic (2.11e-3)" "unprognostic (2.96e-1)" "potential prognostic unfavorable (6.95e-4)" "unprognostic (5.97e-2)" "unprognostic (1.67e-2)" "unprognostic (9.17e-2)" "unprognostic (4.47e-2)" ANKRD34A ANKRD34 ENSG00000272031 "Ankyrin repeat domain 34A" Q69YU3 1 145959441-145964575 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.7" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 7.0;Brain inhibitory neurons: 5.5;Cardiomyocytes: 6.8;Other brain neurons: 5.1;Paneth cells: 3.9;Retinal bipolar cells: 7.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029642, HPA029643" Uncertain Enhanced Cytosol NA NA "Cluster 27: T-cells - Unknown function" "Cluster 27: Cerebellum - Synaptic function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 5: Rhabdoid - Unknown function" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 4 Cytosol "HPA029642: , HPA029643: " "unprognostic (2.14e-1)" "unprognostic (6.65e-3)" "unprognostic (2.67e-1)" "unprognostic (2.37e-2)" "unprognostic (1.51e-1)" "unprognostic (3.75e-1)" "unprognostic (2.44e-1)" ANKRD34B DP58 ENSG00000189127 "Ankyrin repeat domain 34B" A5PLL1 5 80556755-80570280 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 10.7" "Group enriched" "Detected in some" 4 "Brain inhibitory neurons: 40.7;Neutrophils: 80.7" "Cell type enriched" "Detected in many" 4 "medium spiny neuron: 110.1" "Cancer enhanced" "Detected in some" "Prostate Adenocarcinoma (TCGA): 4.5" "Group enriched" "Detected in many" 6 "basal ganglia: 32.8;hypothalamus: 82.8" "Immune cell enriched" "Detected in single" 5 "neutrophil: 3.8" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.8" "Group enriched" "Detected in some" 4 "ovarian cancer: 3.6;Uterine cancer: 5.7" "Adipose visceral - Neutrophils, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA043327 Uncertain Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 78: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 24: Neutrophils - Innate immunity signal integration" 1 "Nucleoplasm, Mitochondria" Cytosol "HPA043327: " "potential prognostic favorable (9.97e-5)" "unprognostic (1.92e-1)" "unprognostic (8.64e-2)" "unprognostic (3.97e-1)" "unprognostic (1.05e-2)" "potential prognostic unfavorable (1.25e-4)" ANKRD34C ENSG00000235711 "Ankyrin repeat domain 34C" P0C6C1 15 79282722-79298239 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 2.6" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 2.4;Brain inhibitory neurons: 1.8;Gonadotrophs: 2.0;Lactotrophs: 2.6;Oocytes: 4.6;Other brain neurons: 2.8;Pancreatic islet cells: 1.8;Retinal amacrine cells: 1.4;Somatotrophs: 2.1;Thyrotrophs: 8.7;Vascular smooth muscle cells: 1.1" "Cell type enhanced" "Detected in many" "mammillary body: 9.2;midbrain-derived inhibitory: 9.0;thalamic excitatory: 7.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Beta cells, Skeletal muscle - Smooth muscle cells, Testis - Early spermatids, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA045329 Approved Mitochondria NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 109: Neurons - Neuronal signaling" Mitochondria "HPA045329: " ANKRD35 FLJ25124 ENSG00000198483 "Ankyrin repeat domain 35" Q8N283 1 145866560-145885866 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 58.1" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 38.7;Endometrial ciliated cells: 91.9;Esophageal apical cells: 113.4;Esophageal suprabasal cells: 68.6;Fibroblasts: 36.9;Lacrimal acinar cells: 35.3;Müller glia: 33.9;Peritubular myoid cells: 40.6;Respiratory secretory cells: 40.5;Suprabasal keratinocytes: 44.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 2.1" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Leukemia: 1.3" "Adrenal gland - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatocytes, Pancreas - Fibroblasts, Skin - Keratinocyte (other), Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA035453 Enhanced Approved "Nucleoplasm,Vesicles,Plasma membrane,Primary cilium,Primary cilium transition zone,Basal body" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 58: Skin - Keratinization" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 108: Fibroblasts - ECM organization" 3 "Plasma membrane" "Nucleoplasm, Vesicles, Primary cilium, Primary cilium transition zone, Basal body" "HPA035453: " "unprognostic (1.72e-2)" "unprognostic (2.03e-2)" "potential prognostic favorable (5.60e-4)" "unprognostic (1.10e-2)" "unprognostic (3.11e-2)" "unprognostic (5.06e-2)" "unprognostic (6.53e-3)" "unprognostic (1.31e-1)" "unprognostic (3.46e-2)" "unprognostic (3.79e-1)" "unprognostic (2.81e-1)" "unprognostic (4.20e-2)" "unprognostic (1.12e-2)" "unprognostic (1.81e-1)" "unprognostic (1.15e-1)" "unprognostic (1.50e-1)" "unprognostic (1.01e-1)" "unprognostic (1.35e-2)" "unprognostic (2.37e-1)" "unprognostic (7.56e-2)" ANKRD36 UNQ2430 ENSG00000135976 "Ankyrin repeat domain 36" A6QL64 2 97113153-97264521 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 18.1" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 354.7;Brain inhibitory neurons: 393.7;Oligodendrocytes: 258.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "HPA051757, HPA057661" Approved Nucleoplasm,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 37: Neurons - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 6 "Nucleoplasm, Cytosol" "HPA051757: , HPA057661: " "unprognostic (3.16e-2)" "unprognostic (8.25e-2)" "unprognostic (2.11e-1)" "potential prognostic unfavorable (4.09e-5)" "unprognostic (9.27e-2)" "unprognostic (7.46e-2)" "unprognostic (2.74e-2)" "unprognostic (1.04e-2)" "unprognostic (1.95e-2)" "unprognostic (2.19e-1)" "unprognostic (2.80e-1)" "unprognostic (5.19e-2)" "unprognostic (9.65e-2)" "unprognostic (9.07e-3)" "unprognostic (3.08e-2)" "unprognostic (9.65e-2)" "unprognostic (2.00e-1)" "unprognostic (1.31e-1)" "unprognostic (8.75e-2)" "potential prognostic unfavorable (7.37e-4)" "unprognostic (8.86e-3)" "unprognostic (4.21e-3)" "unprognostic (4.13e-2)" "unprognostic (1.64e-1)" "unprognostic (9.99e-3)" ANKRD36B "FLJ21281, KIAA1641" ENSG00000196912 "Ankyrin repeat domain 36B" Q8N2N9 2 97492663-97589877 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Lactotrophs: 115.1;Sertoli cells: 198.2;Thyrotrophs: 128.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Skeletal muscle - Fibroblasts" "HPA051757, HPA057661" Approved Nucleoplasm,Cytosol NA NA "Cluster 40: Non-specific - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 56: Non-specific - Sensory perception" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 1 "Nucleoplasm, Cytosol" "HPA051757: , HPA057661: " "unprognostic (3.10e-2)" "unprognostic (4.84e-3)" "unprognostic (2.28e-1)" "unprognostic (3.72e-3)" "unprognostic (2.72e-1)" "unprognostic (3.50e-2)" "unprognostic (3.86e-1)" "unprognostic (1.57e-2)" "unprognostic (1.80e-2)" "potential prognostic unfavorable (4.43e-4)" "unprognostic (7.31e-2)" "unprognostic (3.82e-1)" "unprognostic (1.20e-1)" "unprognostic (9.58e-2)" "unprognostic (2.70e-1)" "unprognostic (4.20e-2)" "unprognostic (1.02e-1)" "unprognostic (1.40e-2)" "unprognostic (4.43e-2)" "unprognostic (1.14e-3)" "unprognostic (2.31e-1)" "unprognostic (3.47e-2)" "potential prognostic favorable (6.35e-5)" "unprognostic (1.30e-1)" "unprognostic (2.13e-2)" "unprognostic (7.67e-2)" "unprognostic (1.48e-1)" ANKRD36C DKFZp667P0924 ENSG00000174501 "Ankyrin repeat domain 36C" Q5JPF3 2 95836919-95991831 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 13.9;salivary gland: 14.6" "Cell type enhanced" "Detected in many" "Foveolar cells: 1110.4;Salivary acinar cells: 1052.2;Sertoli cells: 1194.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "HPA051757, HPA057661" Approved Nucleoplasm,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 40: Non-specific - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 38: Secretory epithelial cells - Exocrine secretion" "Nucleoplasm, Cytosol" "HPA051757: , HPA057661: " "unprognostic (1.37e-1)" "unprognostic (1.47e-2)" "unprognostic (2.10e-2)" "unprognostic (1.57e-1)" "unprognostic (1.18e-1)" "unprognostic (1.35e-2)" "potential prognostic favorable (5.31e-4)" "unprognostic (4.90e-2)" "unprognostic (3.73e-1)" "unprognostic (5.48e-2)" "unprognostic (2.43e-2)" "unprognostic (1.66e-1)" "unprognostic (3.62e-1)" "unprognostic (5.09e-2)" "unprognostic (5.18e-2)" "unprognostic (8.47e-3)" "unprognostic (1.08e-2)" "potential prognostic unfavorable (1.13e-4)" "unprognostic (2.58e-3)" "unprognostic (3.90e-3)" "unprognostic (1.19e-1)" "unprognostic (2.62e-1)" ANKRD37 Lrp2bp ENSG00000186352 "Ankyrin repeat domain 37" Q7Z713 4 185396021-185400628 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 9 "Esophageal apical cells: 4834.8;Pancreatic acinar cells: 1236.4" "Cell type enhanced" "Detected in all" "endothelial cell: 142.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Myeloma: 64.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036626, HPA058127" Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 3: Choroid plexus - Cilium" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 84: Apical squamous epithelium - Cornification" 2 "Nucleoplasm, Cytosol" "HPA036626: , HPA058127: " "unprognostic (2.13e-2)" "unprognostic (3.85e-2)" "unprognostic (1.55e-3)" "unprognostic (9.56e-3)" "unprognostic (5.61e-2)" "unprognostic (1.60e-2)" "unprognostic (7.20e-2)" "unprognostic (8.53e-2)" "unprognostic (1.17e-1)" "unprognostic (1.14e-1)" "unprognostic (2.10e-2)" "unprognostic (1.09e-2)" "unprognostic (1.63e-1)" "unprognostic (8.47e-2)" "unprognostic (1.14e-1)" "unprognostic (1.64e-2)" "unprognostic (9.53e-3)" "unprognostic (1.68e-1)" "unprognostic (4.21e-1)" "unprognostic (2.19e-2)" "unprognostic (1.78e-1)" "unprognostic (1.67e-2)" "unprognostic (2.09e-3)" "unprognostic (8.50e-2)" "unprognostic (7.88e-2)" "unprognostic (1.02e-1)" "unprognostic (1.98e-1)" "unprognostic (1.31e-1)" "unprognostic (1.19e-1)" "unprognostic (3.49e-3)" "unprognostic (3.98e-2)" ANKRD39 MGC41816 ENSG00000213337 "Ankyrin repeat domain 39" Q53RE8 2 96836611-96858016 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric chief cells: 13.1;Melanocytes: 8.7;Oocytes: 13.8" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042678 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 35: Non-specific - Mixed function" "Cluster 34: Non-specific - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 97: Non-specific - Cellular respiration" 16 Nucleoplasm Vesicles "HPA042678: " "unprognostic (4.11e-2)" "unprognostic (6.92e-3)" "unprognostic (1.10e-2)" "unprognostic (2.36e-1)" "unprognostic (1.24e-3)" "unprognostic (9.56e-2)" "potential prognostic unfavorable (4.81e-4)" "potential prognostic favorable (7.16e-4)" "unprognostic (1.08e-1)" "unprognostic (7.09e-3)" "unprognostic (4.62e-2)" "unprognostic (1.37e-1)" "unprognostic (7.03e-2)" "unprognostic (8.48e-3)" "potential prognostic unfavorable (7.86e-5)" "unprognostic (2.01e-1)" "unprognostic (4.29e-2)" "unprognostic (1.05e-1)" "unprognostic (1.84e-1)" "unprognostic (3.52e-2)" "unprognostic (8.40e-2)" "unprognostic (1.06e-2)" "unprognostic (2.11e-1)" "unprognostic (2.72e-1)" "unprognostic (1.64e-1)" "unprognostic (1.46e-2)" "unprognostic (7.05e-2)" "unprognostic (1.29e-2)" "unprognostic (3.77e-2)" "unprognostic (9.52e-2)" "unprognostic (1.80e-1)" ANKRD40 MGC15396 ENSG00000154945 "Ankyrin repeat domain 40" Q6AI12 17 50693198-50707914 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 196.0" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021668, HPA021759, HPA074884" Uncertain Approved "Nucleoli fibrillar center,Golgi apparatus,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 33 "Golgi apparatus" "Nucleoli fibrillar center, Cytosol" "HPA021668: , HPA021759: , HPA074884: " "unprognostic (1.38e-2)" "unprognostic (2.60e-1)" "unprognostic (7.65e-2)" "unprognostic (6.26e-3)" "unprognostic (3.53e-1)" "unprognostic (1.02e-2)" "unprognostic (3.13e-1)" "unprognostic (3.87e-3)" "unprognostic (2.03e-1)" "unprognostic (9.98e-3)" "potential prognostic favorable (6.42e-6)" "unprognostic (1.57e-3)" "unprognostic (1.05e-2)" "unprognostic (1.50e-3)" "potential prognostic unfavorable (5.39e-4)" "unprognostic (2.16e-1)" "unprognostic (6.15e-3)" "unprognostic (1.49e-2)" "unprognostic (3.56e-2)" "unprognostic (3.90e-1)" "unprognostic (5.49e-2)" "unprognostic (6.15e-2)" "unprognostic (1.03e-1)" "unprognostic (1.10e-1)" "unprognostic (1.71e-1)" "potential prognostic favorable (9.71e-4)" "unprognostic (1.37e-1)" "unprognostic (1.40e-2)" "unprognostic (2.96e-1)" "unprognostic (5.45e-2)" "unprognostic (6.92e-2)" ANKRD40CL "C17orf73, FLJ20694, LINC00483" ENSG00000167117 "ANKRD40 C-terminal like" Q53H64 17 50761029-50767557 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "intestine: 56.4" "Cell type enhanced" "Detected in some" "Colonocytes: 144.0;Enteric stem cells: 27.1;Enteric transient amplifying cells: 56.4;Enterocytes: 289.3;Gastric progenitor cells: 26.9;Goblet cells: 45.6;Neuroendocrine cells: 21.3;Paneth cells: 50.3;Tuft cells: 57.6" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Colon Adenocarcinoma (TCGA): 21.4;Pancreatic Adenocarcinoma (TCGA): 6.2;Rectum Adenocarcinoma (TCGA): 21.7;Stomach Adenocarcinoma (TCGA): 10.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.8" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.8" "Cancer enhanced" "Detected in many" "colorectal cancer: 11.9;Gastric cancer: 9.1" "Colon - Colon enterocytes, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 6: Non-specific - Immune response" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" "unprognostic (9.39e-2)" "unprognostic (2.50e-1)" "unprognostic (1.15e-2)" "unprognostic (2.92e-2)" "unprognostic (3.61e-1)" "unprognostic (5.09e-2)" "potential prognostic unfavorable (5.25e-4)" "unprognostic (2.38e-1)" "unprognostic (1.30e-1)" "unprognostic (1.27e-2)" "unprognostic (3.44e-2)" "unprognostic (2.30e-2)" "unprognostic (2.53e-1)" "unprognostic (1.01e-1)" "unprognostic (7.64e-2)" "unprognostic (2.88e-1)" "unprognostic (1.42e-2)" "unprognostic (1.12e-1)" "unprognostic (7.64e-3)" "unprognostic (1.49e-2)" ANKRD42 "FLJ37874, PPP1R79, SARP" ENSG00000137494 "Ankyrin repeat domain 42" Q8N9B4 11 83193712-83260694 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 34.8" "Cell type enhanced" "Detected in many" "Early spermatids: 164.9;Endometrial ciliated cells: 117.3;Ependymal cells: 95.5;Fallopian tube ciliated cells: 108.2;Late primary spermatocytes: 159.0;Respiratory ciliated cells: 107.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039917 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" No No "Cluster 32: Basophils - Transcription" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 29: Neutrophils - Innate immune cellular maintenance" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA039917: " "unprognostic (1.75e-1)" "unprognostic (1.30e-1)" "unprognostic (1.62e-1)" "unprognostic (9.54e-2)" "unprognostic (2.12e-1)" "unprognostic (2.48e-2)" "unprognostic (1.72e-1)" "potential prognostic unfavorable (3.25e-4)" "unprognostic (2.69e-1)" "unprognostic (1.29e-3)" "potential prognostic favorable (2.64e-4)" "unprognostic (4.88e-2)" "unprognostic (2.79e-3)" "unprognostic (6.40e-2)" "unprognostic (2.29e-3)" "unprognostic (1.76e-1)" "unprognostic (1.37e-3)" "unprognostic (5.21e-2)" "unprognostic (1.57e-1)" "unprognostic (1.40e-1)" "unprognostic (1.07e-1)" "unprognostic (1.53e-1)" "unprognostic (5.25e-2)" "unprognostic (1.52e-2)" "unprognostic (1.66e-2)" "unprognostic (9.39e-2)" "unprognostic (1.34e-2)" "unprognostic (6.35e-2)" "unprognostic (2.65e-1)" "unprognostic (1.26e-1)" "unprognostic (4.38e-2)" ANKRD44 PP6-ARS-B ENSG00000065413 "Ankyrin repeat domain 44" Q8N8A2 2 196967017-197311173 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 34.2" "Cell type enhanced" "Detected in all" "B-cells: 1469.9;cDC: 603.5;Mast cells: 580.9;Microglia: 1514.8;Neutrophil progenitors: 580.3;Neutrophils: 1924.8;NK-cells: 722.4;Podocytes: 727.1;T-cells: 778.9;Thymocytes: 893.5" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 1843.5;leukocyte: 1308.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "lymphoma: 28.7" "Adipose visceral - T-cells, Prostate - Fibroblasts, Spleen - B-cells (Spleen), Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030122, HPA056549" Approved Approved "Nuclear speckles,Mitochondria" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 22 Mitochondria "Nuclear speckles" "HPA030122: , HPA056549: " "unprognostic (9.88e-3)" "unprognostic (3.52e-1)" "unprognostic (2.00e-2)" "unprognostic (6.04e-2)" "unprognostic (2.39e-2)" "unprognostic (1.01e-1)" "unprognostic (1.78e-1)" "unprognostic (8.08e-3)" "potential prognostic favorable (3.19e-4)" "unprognostic (8.07e-2)" "unprognostic (3.90e-3)" "unprognostic (1.78e-1)" "unprognostic (2.06e-1)" "unprognostic (2.67e-2)" "unprognostic (8.54e-2)" "unprognostic (1.94e-3)" "unprognostic (2.41e-2)" "unprognostic (3.83e-1)" "unprognostic (4.78e-2)" "unprognostic (2.04e-1)" "unprognostic (9.28e-2)" "unprognostic (3.12e-2)" "unprognostic (2.44e-1)" "unprognostic (2.28e-1)" "unprognostic (1.74e-1)" "unprognostic (2.50e-2)" "unprognostic (3.64e-1)" "unprognostic (2.65e-2)" "unprognostic (3.26e-3)" "unprognostic (2.80e-1)" "unprognostic (4.11e-2)" ANKRD45 "CT117, FLJ45235" ENSG00000183831 "Ankyrin repeat domain 45" Q5TZF3 1 173608336-173669851 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 6.0;fallopian tube: 11.9;parathyroid gland: 8.7" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 2.4;Endometrial ciliated cells: 2.3;Fallopian tube ciliated cells: 2.2;Loop of henle epithelial cells: 4.8;Papillary tip epithelial cells: 2.4;Podocytes: 4.6;Proximal tubule cells: 3.2;Renal collecting duct intercalated cells: 1.5;Renal collecting duct principal cells: 12.9;Renal connecting tubule cells: 9.2" "Cell type enhanced" "Detected in single" "ependymal cell: 1.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 2.3" "Lung - Respiratory ciliated cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031655, HPA031656, HPA031657" Enhanced Supported "Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" Cytosol "Plasma membrane, Centrosome" "HPA031655: , HPA031656: , HPA031657: " "unprognostic (1.92e-1)" "unprognostic (1.81e-3)" "potential prognostic unfavorable (4.29e-4)" "unprognostic (3.22e-2)" "unprognostic (1.25e-1)" "unprognostic (2.76e-2)" "unprognostic (4.01e-2)" "unprognostic (7.79e-2)" "unprognostic (1.05e-1)" "unprognostic (1.88e-1)" "unprognostic (7.52e-2)" "unprognostic (8.89e-2)" ANKRD46 ENSG00000186106 "Ankyrin repeat domain 46" Q86W74 8 100509752-100559784 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013758 Approved Approved Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 40: Non-specific - Unknown function" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 20 Cytosol "HPA013758: " "unprognostic (5.01e-2)" "unprognostic (3.68e-3)" "potential prognostic unfavorable (4.15e-4)" "unprognostic (1.31e-3)" "unprognostic (2.49e-1)" "unprognostic (1.42e-1)" "unprognostic (5.13e-2)" "unprognostic (1.51e-2)" "unprognostic (1.91e-1)" "unprognostic (1.36e-1)" "validated prognostic favorable (2.46e-9)" "validated prognostic favorable (1.24e-4)" "unprognostic (1.89e-1)" "unprognostic (2.64e-1)" "unprognostic (1.83e-1)" "unprognostic (7.09e-2)" "unprognostic (2.44e-1)" "unprognostic (3.82e-1)" "unprognostic (2.40e-2)" "unprognostic (7.14e-2)" "unprognostic (2.78e-2)" "unprognostic (2.60e-1)" "unprognostic (4.03e-2)" "unprognostic (1.65e-1)" "unprognostic (3.37e-2)" "unprognostic (2.45e-2)" "unprognostic (1.12e-1)" "unprognostic (1.39e-1)" "unprognostic (2.43e-1)" "unprognostic (9.02e-3)" "unprognostic (1.22e-1)" ANKRD49 "FGIF, FLJ20189, GBIF" ENSG00000168876 "Ankyrin repeat domain 49" Q8WVL7 11 94493979-94499578 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040273, HPA048137" Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 15: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 32 "Nucleoplasm, Nucleoli" "Golgi apparatus" "HPA040273: , HPA048137: " "unprognostic (5.77e-2)" "potential prognostic unfavorable (1.21e-4)" "unprognostic (4.60e-2)" "unprognostic (1.99e-1)" "unprognostic (2.13e-2)" "unprognostic (8.53e-2)" "unprognostic (4.68e-2)" "unprognostic (2.28e-2)" "unprognostic (1.34e-1)" "unprognostic (5.55e-3)" "potential prognostic favorable (7.92e-4)" "unprognostic (5.56e-2)" "unprognostic (3.10e-2)" "potential prognostic unfavorable (4.39e-4)" "unprognostic (4.89e-2)" "unprognostic (3.16e-1)" "unprognostic (7.48e-2)" "unprognostic (1.05e-1)" "unprognostic (6.81e-2)" "unprognostic (1.90e-1)" "unprognostic (1.33e-1)" "unprognostic (1.28e-1)" "unprognostic (2.20e-3)" "unprognostic (1.03e-1)" "potential prognostic favorable (5.22e-4)" "unprognostic (7.20e-2)" "unprognostic (7.19e-3)" "unprognostic (5.28e-2)" "unprognostic (3.83e-1)" "unprognostic (9.76e-2)" "unprognostic (3.07e-1)" ANKRD50 KIAA1223 ENSG00000151458 "Ankyrin repeat domain containing 50" Q9ULJ7 4 124664048-124712732 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late spermatids: 91.7;Prostatic glandular cells: 83.0;Urothelial cells: 82.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "intermediate monocyte: 1.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044008 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 1: Neurons - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 69: Urothelial cells - Basic cellular functions" 7 "Nucleoplasm, Cytosol" "HPA044008: " "unprognostic (8.94e-3)" "unprognostic (1.34e-1)" "unprognostic (3.84e-1)" "unprognostic (3.91e-3)" "unprognostic (1.86e-1)" "unprognostic (2.86e-1)" "unprognostic (1.28e-1)" "unprognostic (3.94e-2)" "unprognostic (3.40e-1)" "unprognostic (1.88e-2)" "validated prognostic favorable (3.56e-5)" "validated prognostic favorable (3.84e-4)" "unprognostic (1.09e-1)" "unprognostic (2.19e-1)" "unprognostic (3.14e-1)" "unprognostic (2.28e-2)" "potential prognostic unfavorable (5.85e-5)" "unprognostic (1.42e-1)" "unprognostic (1.50e-1)" "unprognostic (7.03e-2)" "unprognostic (2.03e-3)" "potential prognostic unfavorable (2.52e-4)" "unprognostic (4.72e-2)" "unprognostic (6.90e-2)" "unprognostic (6.31e-2)" "unprognostic (4.17e-3)" "unprognostic (1.00e-1)" "unprognostic (2.64e-2)" "unprognostic (7.91e-2)" "unprognostic (1.63e-2)" "unprognostic (1.40e-1)" ANKRD52 "FLJ34236, PP6-ARS-C" ENSG00000139645 "Ankyrin repeat domain 52" Q8NB46 12 56237807-56258384 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 81.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043815 Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 24: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 25 "Nucleoplasm, Mitochondria" "HPA043815: " "unprognostic (2.25e-1)" "unprognostic (4.61e-3)" "unprognostic (1.92e-1)" "unprognostic (1.36e-2)" "unprognostic (4.19e-3)" "unprognostic (3.09e-2)" "unprognostic (1.35e-1)" "unprognostic (8.54e-2)" "unprognostic (1.96e-1)" "unprognostic (2.92e-3)" "unprognostic (7.21e-2)" "unprognostic (1.21e-1)" "unprognostic (1.94e-3)" "potential prognostic unfavorable (1.65e-4)" "unprognostic (1.67e-2)" "unprognostic (2.29e-2)" "unprognostic (3.90e-1)" "unprognostic (9.57e-2)" "unprognostic (1.55e-3)" "unprognostic (1.02e-1)" "unprognostic (1.22e-2)" "unprognostic (1.43e-2)" "unprognostic (1.36e-1)" "unprognostic (3.24e-1)" "unprognostic (2.42e-2)" "unprognostic (1.21e-1)" "unprognostic (6.15e-3)" "unprognostic (2.55e-2)" "unprognostic (1.10e-1)" "unprognostic (2.01e-2)" "unprognostic (2.72e-1)" ANKRD53 "FLJ12056, FLJ36160" ENSG00000144031 "Ankyrin repeat domain 53" Q8N9V6 2 70978380-70985499 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 25.3" "Cell type enriched" "Detected in many" 4 "Late spermatids: 814.5" "Cell type enriched" "Detected in many" 4 "ependymal cell: 18.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "plasmacytoid DC: 7.1" "Lineage enriched" "Detected in many" 5 "dendritic cells: 7.1" "Not detected" "Not detected" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA049574 Approved NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 47: Testis - Mixed function" "Cluster 2: Neurons - Nucleosome" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" "HPA049574: " "unprognostic (2.19e-2)" "unprognostic (2.08e-2)" "unprognostic (3.76e-2)" "unprognostic (2.27e-1)" "unprognostic (7.15e-2)" "unprognostic (1.13e-1)" "unprognostic (1.07e-1)" "unprognostic (2.90e-1)" "unprognostic (2.35e-1)" "unprognostic (9.53e-3)" "unprognostic (6.89e-2)" ANKRD54 LIAR ENSG00000100124 "Ankyrin repeat domain 54" Q6NXT1 22 37830855-37849327 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 75.3;Epididymal efferent duct ciliated cells: 95.7;Fallopian tube ciliated cells: 77.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071287 Approved Approved Nucleoplasm,Microtubules,Midbody Yes No "Cluster 25: Non-specific - Unknown function" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 107: Ciliated cells - Cilia assembly & function" 23 "Microtubules, Midbody" Nucleoplasm "HPA071287: " "unprognostic (3.14e-2)" "unprognostic (1.36e-1)" "unprognostic (9.37e-3)" "unprognostic (1.69e-1)" "unprognostic (2.19e-3)" "unprognostic (5.26e-2)" "unprognostic (1.19e-2)" "unprognostic (1.35e-1)" "unprognostic (4.15e-2)" "unprognostic (3.76e-2)" "unprognostic (3.35e-1)" "unprognostic (9.98e-3)" "unprognostic (7.29e-3)" "unprognostic (9.38e-3)" "unprognostic (7.63e-2)" "unprognostic (1.50e-1)" "unprognostic (2.48e-1)" "unprognostic (7.23e-2)" "unprognostic (7.36e-2)" "unprognostic (4.20e-2)" "unprognostic (3.26e-2)" "unprognostic (3.28e-2)" "unprognostic (1.18e-2)" "unprognostic (4.53e-2)" "unprognostic (1.66e-1)" "unprognostic (1.27e-1)" "unprognostic (2.97e-1)" "unprognostic (2.17e-1)" "unprognostic (1.56e-2)" "unprognostic (2.57e-2)" "unprognostic (1.15e-1)" ANKRD55 FLJ11795 ENSG00000164512 "Ankyrin repeat domain 55" Q3KP44 5 56099680-56233330 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.8;lymphoid tissue: 3.4;testis: 9.2" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 83.5;Early spermatids: 151.9;Endometrial glandular cells: 211.0;Epicardial cells: 138.7;Late primary spermatocytes: 178.6;Late spermatids: 40.1;Neutrophils: 50.6;Oligodendrocyte progenitor cells: 58.0;Other brain neurons: 78.6;Platelets: 80.7;Retinal amacrine cells: 62.1" "Group enriched" "Detected in all" 4 "CGE interneuron: 162.8;committed oligodendrocyte precursor: 47.1;eccentric medium spiny neuron: 105.6;LAMP5-LHX6 and Chandelier: 152.4;lower rhombic lip: 88.1;medium spiny neuron: 75.3;MGE interneuron: 132.2;midbrain-derived inhibitory: 94.6;oligodendrocyte precursor cell: 89.6;splatter: 84.2" "Cancer enriched" "Detected in single" 6 "Testicular Germ Cell Tumor (TCGA): 2.4" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "basophil: 23.1;eosinophil: 20.8;naive CD4 T-cell: 19.9" "Group enriched" "Detected in many" 74 "granulocytes: 23.1;T-cells: 19.9" "Cancer enhanced" "Detected in some" "Leukemia: 7.0;lymphoma: 3.6" "Liver - Sinusoid Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA051049, HPA061649" Uncertain Approved "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 39: Testis - Nuclear processes" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 50: Lymphoma - Unknown function" "Cluster 51: Secretory epithelial cells - Mixed function" 30 "Nucleoplasm, Nuclear speckles" Cytosol "HPA051049: , HPA061649: " "unprognostic (2.31e-2)" "unprognostic (2.45e-1)" ANKRD6 KIAA0957 ENSG00000135299 "Ankyrin repeat domain 6" Q9Y2G4 6 89433152-89633834 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 25.8" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 175.9;Medullary thymic epithelial cells: 187.2;Pituitary stem cells: 174.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Fibroblasts, Pituitary gland - Undifferentiated cells (Pituitary gland)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020693, HPA035694, HPA064642" Approved Enhanced Vesicles NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 27: Cerebellum - Synaptic function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 1 Vesicles "CAB020693: , HPA035694: , HPA064642: " "unprognostic (4.94e-3)" "unprognostic (1.84e-1)" "unprognostic (1.59e-1)" "unprognostic (1.11e-1)" "unprognostic (1.19e-1)" "unprognostic (1.23e-1)" "unprognostic (6.22e-2)" "unprognostic (4.65e-3)" "unprognostic (5.86e-2)" "potential prognostic favorable (8.82e-9)" "unprognostic (3.16e-3)" "unprognostic (2.45e-2)" "unprognostic (2.58e-2)" "unprognostic (3.24e-1)" "unprognostic (2.49e-2)" "unprognostic (1.85e-3)" "unprognostic (1.78e-1)" "unprognostic (8.07e-2)" "unprognostic (8.43e-2)" "unprognostic (6.23e-2)" "unprognostic (2.20e-1)" "unprognostic (7.19e-2)" "unprognostic (3.41e-2)" "unprognostic (4.03e-2)" "unprognostic (2.04e-1)" "unprognostic (4.12e-3)" "unprognostic (4.70e-1)" "unprognostic (1.00e-1)" "unprognostic (1.81e-1)" ANKRD60 "bA196N14.3, C20orf86" ENSG00000124227 "Ankyrin repeat domain 60" Q9BZ19 20 58216126-58228653 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 13 "testis: 3.5" "Cell type enhanced" "Detected in some" "Early spermatids: 5.4;Late primary spermatocytes: 3.2;Late spermatids: 13.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.1" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA060561 Uncertain NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 6: Non-specific - Immune response" "Cluster 7: Liver cancer - Metabolism" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" "HPA060561: " ANKRD61 ENSG00000157999 "Ankyrin repeat domain 61" A6NGH8 7 6031376-6036552 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "bone marrow: 5.7;testis: 5.6" "Group enriched" "Detected in some" 4 "Early spermatids: 65.7;Late primary spermatocytes: 41.9;Late spermatids: 34.2" "Low cell type specificity" "Detected in some" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA029511, HPA050732" Uncertain Enhanced Nucleoplasm NA NA "Cluster 44: Bone marrow - Nuclear processes" "Cluster 6: Non-specific - Immune response" "Cluster 56: Non-specific - Sensory perception" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" Nucleoplasm "HPA029511: , HPA050732: " "unprognostic (4.30e-2)" "unprognostic (2.98e-2)" "unprognostic (1.65e-2)" "unprognostic (2.30e-1)" "unprognostic (3.65e-1)" ANKRD62 DKFZp779B1634 ENSG00000181626 "Ankyrin repeat domain 62" A6NC57 18 12093843-12129764 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "testis: 1.3" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 18.5;Early primary spermatocytes: 105.0;Esophageal apical cells: 22.8;Late primary spermatocytes: 30.2;Pancreatic acinar cells: 38.5;Undifferentiated spermatogonia: 11.6" "Cell type enhanced" "Detected in many" "deep-layer corticothalamic and 6b: 25.9;hippocampal dentate gyrus: 20.8;thalamic excitatory: 22.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Spermatocytes" "Not detected" "Not detected" HPA059835 Enhanced Uncertain "Nucleoplasm,Nuclear bodies,Actin filaments" NA NA "Cluster 21: Testis - Mixed function" "Cluster 24: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 3: Early primary spermatocytes - Early meiosis" "Nucleoplasm, Nuclear bodies" "Actin filaments" "HPA059835: " "unprognostic (2.24e-2)" ANKRD63 ENSG00000230778 "Ankyrin repeat domain 63" C9JTQ0 15 40278372-40283064 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 24 "brain: 17.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in many" "basal ganglia: 34.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Bone cancer: 7.0" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Testis - Sertoli cells" "Region enhanced" "Detected in many" "basal ganglia: 56.7" "Region enhanced" "Detected in many" "basal ganglia: 44.0" HPA066743 Approved Mitochondria NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" Mitochondria "HPA066743: " ANKRD65 ENSG00000235098 "Ankyrin repeat domain 65" E5RJM6 1 1418420-1421769 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 38.7" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 83.5;Fallopian secretory cells: 43.4;Fallopian tube ciliated cells: 135.0;Prostatic hillock cells: 45.3;Respiratory ciliated cells: 60.2;Smooth muscle cells: 41.6" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Bladder Urothelial Carcinoma (TCGA): 89.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 16 "myeloid DC: 3.5;plasmacytoid DC: 7.9" "Lineage enriched" "Detected in single" 23 "dendritic cells: 7.9" "Cancer enhanced" "Detected in many" "Bladder cancer: 21.1;head and neck cancer: 18.1" "Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1" "Not detected" "Not detected" HPA065720 Enhanced Approved "Nucleoplasm,Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Primary cilium tip" Yes NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 38: Secretory epithelial cells - Exocrine secretion" "Nucleoplasm, Microtubules, Primary cilium" "Cytokinetic bridge, Mitotic spindle, Primary cilium tip" "HPA065720: " "unprognostic (3.48e-2)" "unprognostic (4.88e-2)" "unprognostic (4.82e-2)" "unprognostic (2.99e-2)" "unprognostic (3.66e-1)" "unprognostic (2.20e-1)" "unprognostic (3.55e-2)" "unprognostic (1.52e-2)" "potential prognostic favorable (3.05e-4)" "unprognostic (2.43e-2)" "unprognostic (5.48e-3)" "unprognostic (2.57e-2)" "unprognostic (1.85e-1)" "potential prognostic favorable (1.52e-5)" "unprognostic (1.90e-1)" "unprognostic (8.68e-2)" "unprognostic (1.96e-1)" "unprognostic (4.24e-2)" "unprognostic (1.55e-1)" "unprognostic (1.22e-1)" "unprognostic (8.13e-2)" "unprognostic (4.30e-2)" "unprognostic (2.63e-3)" "unprognostic (6.13e-2)" "unprognostic (1.91e-2)" "unprognostic (1.73e-2)" "unprognostic (2.49e-2)" "unprognostic (1.70e-1)" "unprognostic (9.57e-2)" ANKRD66 ENSG00000230062 "Ankyrin repeat domain 66" B4E2M5 6 46746933-46759506 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "fallopian tube: 38.3" "Group enriched" "Detected in some" 4 "Endometrial ciliated cells: 114.5;Epididymal efferent duct ciliated cells: 137.7;Fallopian tube ciliated cells: 243.0;Respiratory ciliated cells: 208.8" "Cell type enriched" "Detected in single" 124 "ependymal cell: 58.7" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 3.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 107: Ciliated cells - Cilia assembly & function" "potential prognostic favorable (2.84e-4)" "unprognostic (1.40e-1)" "unprognostic (4.18e-1)" ANKRD7 TSA806 ENSG00000106013 "Ankyrin repeat domain 7" Q92527 7 118214669-118496171 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 426 "testis: 803.6" "Group enriched" "Detected in many" 4 "Early spermatids: 2845.4;Late primary spermatocytes: 7264.6" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 3.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" "HPA043489, HPA052941" Enhanced Nucleoplasm NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 1: Neurons - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" Nucleoplasm "HPA043489: , HPA052941: " "unprognostic (5.43e-3)" "unprognostic (1.07e-3)" "unprognostic (8.20e-2)" "unprognostic (6.51e-2)" "unprognostic (9.29e-2)" ANKRD9 ENSG00000156381 "Ankyrin repeat domain 9" Q96BM1 14 102501767-102509799 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 104.9;skeletal muscle: 148.8" "Cell type enhanced" "Detected in many" "Colonocytes: 159.7;Early spermatids: 182.4;Enterocytes: 118.6;Esophageal apical cells: 116.1;Platelets: 240.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Stomach - Gastric mucous cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055985 Uncertain NA NA "Cluster 52: Non-specific - Cellular respiration" "Cluster 18: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 16 "HPA055985: " "unprognostic (9.39e-3)" "unprognostic (1.89e-1)" "unprognostic (3.54e-2)" "potential prognostic unfavorable (5.90e-4)" "unprognostic (1.48e-2)" "unprognostic (1.07e-1)" "unprognostic (1.63e-1)" "unprognostic (5.22e-2)" "unprognostic (6.02e-3)" "unprognostic (2.31e-1)" "unprognostic (2.73e-2)" "unprognostic (9.85e-2)" "unprognostic (1.29e-2)" "unprognostic (1.56e-2)" "unprognostic (1.12e-1)" "unprognostic (1.15e-2)" "unprognostic (6.74e-3)" "unprognostic (6.32e-2)" "unprognostic (5.88e-2)" "unprognostic (9.07e-2)" "unprognostic (2.97e-2)" "unprognostic (3.17e-1)" "unprognostic (2.27e-1)" "unprognostic (3.36e-2)" "unprognostic (4.43e-2)" "unprognostic (3.27e-2)" "unprognostic (3.60e-1)" "unprognostic (1.61e-1)" "unprognostic (1.84e-1)" "unprognostic (1.34e-3)" "unprognostic (6.19e-2)" ANKS1A "ANKS1, KIAA0229" ENSG00000064999 "Ankyrin repeat and sterile alpha motif domain containing 1A" Q92625 6 34889255-35091406 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 550.5;Neutrophils: 666.8;Sertoli cells: 841.0" "Cell type enhanced" "Detected in all" "endothelial cell: 713.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 4.4" "Group enriched" "Detected in many" 4 "dendritic cells: 4.4;granulocytes: 1.2;monocytes: 1.8" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036768, HPA036769" Approved Approved Nucleoplasm,Cytosol NA NA 6000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 69: Skin cancer - ECM organization" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 34 Nucleoplasm Cytosol "HPA036768: , HPA036769: " "unprognostic (8.43e-3)" "unprognostic (2.43e-2)" "unprognostic (2.25e-1)" "unprognostic (2.15e-1)" "unprognostic (2.60e-2)" "unprognostic (2.36e-1)" "unprognostic (2.31e-2)" "unprognostic (5.82e-3)" "potential prognostic favorable (6.34e-4)" "unprognostic (1.04e-1)" "potential prognostic favorable (3.11e-5)" "unprognostic (2.70e-3)" "unprognostic (9.45e-2)" "unprognostic (2.86e-3)" "unprognostic (1.47e-2)" "unprognostic (4.14e-2)" "unprognostic (2.00e-1)" "unprognostic (1.80e-1)" "unprognostic (2.22e-2)" "unprognostic (8.03e-2)" "unprognostic (2.18e-1)" "unprognostic (1.98e-1)" "unprognostic (4.17e-1)" "unprognostic (7.67e-2)" "potential prognostic favorable (6.22e-4)" "unprognostic (4.64e-2)" "unprognostic (2.89e-1)" "unprognostic (7.78e-2)" "unprognostic (1.71e-1)" "unprognostic (2.72e-2)" "unprognostic (3.31e-1)" ANKS1B "AIDA-1, ANKS2, cajalin-2, EB-1" ENSG00000185046 "Ankyrin repeat and sterile alpha motif domain containing 1B" Q7Z6G8 12 98726457-99984936 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 66.3" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 2344.8;Brain inhibitory neurons: 2616.6;Oligodendrocyte progenitor cells: 2402.2;Oligodendrocytes: 1226.4;Other brain neurons: 1284.1;Retinal amacrine cells: 1086.5;Retinal ganglion cells: 772.6" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 11.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Stomach - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078230 Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 78: Brain - Neuronal signaling" "Cluster 34: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 35: Neurons - Synaptic function & neurogenesis" 3 Nucleoplasm "Plasma membrane" "HPA078230: " "unprognostic (1.32e-1)" "unprognostic (1.55e-1)" "unprognostic (3.21e-1)" "potential prognostic favorable (8.31e-5)" "unprognostic (2.71e-1)" "unprognostic (3.50e-1)" "unprognostic (1.69e-3)" "unprognostic (2.37e-1)" "unprognostic (7.73e-2)" "unprognostic (2.23e-2)" "unprognostic (2.45e-1)" "unprognostic (1.26e-2)" "unprognostic (6.27e-2)" "unprognostic (6.00e-2)" "unprognostic (2.37e-1)" "unprognostic (2.42e-1)" "unprognostic (3.79e-3)" "unprognostic (6.92e-2)" "unprognostic (2.16e-2)" "unprognostic (4.24e-2)" "unprognostic (3.41e-2)" "unprognostic (8.46e-2)" "unprognostic (2.88e-3)" "unprognostic (8.31e-3)" "unprognostic (3.39e-1)" ANKS3 "FLJ32345, FLJ32767, KIAA1977" ENSG00000168096 "Ankyrin repeat and sterile alpha motif domain containing 3" Q6ZW76 16 4696510-4734378 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041409, HPA041482" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 64: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 79: Photoreceptor cells - Phototransduction" 9 Nucleoplasm Cytosol "HPA041409: , HPA041482: " "unprognostic (3.77e-2)" "unprognostic (3.89e-3)" "unprognostic (1.96e-1)" "unprognostic (1.31e-2)" "unprognostic (3.56e-2)" "unprognostic (1.36e-1)" "unprognostic (1.85e-1)" "potential prognostic favorable (8.63e-4)" "unprognostic (1.34e-3)" "unprognostic (2.18e-1)" "unprognostic (1.85e-2)" "unprognostic (1.27e-1)" "unprognostic (6.00e-2)" "potential prognostic unfavorable (4.45e-5)" "unprognostic (5.16e-2)" "unprognostic (2.74e-1)" "unprognostic (4.44e-1)" "unprognostic (2.76e-2)" "unprognostic (1.36e-1)" "unprognostic (2.12e-2)" "unprognostic (3.33e-2)" "unprognostic (3.80e-1)" "unprognostic (2.79e-2)" "unprognostic (3.02e-2)" "unprognostic (1.09e-1)" "unprognostic (8.03e-2)" "unprognostic (1.39e-1)" "unprognostic (2.70e-1)" "unprognostic (1.54e-1)" "unprognostic (8.34e-2)" "unprognostic (1.14e-1)" ANKS4B "FLJ38819, HARP" ENSG00000175311 "Ankyrin repeat and sterile alpha motif domain containing 4B" Q8N8V4 16 21233699-21253850 "Predicted intracellular proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "intestine: 11.9;kidney: 5.5;liver: 13.0" "Cell type enriched" "Detected in some" 9 "Proximal tubule cells: 40.7" "Cell type enhanced" "Detected in many" "deep-layer near-projecting: 6.5;medium spiny neuron: 6.2;upper rhombic lip: 8.5" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 8.3;Rectum Adenocarcinoma (TCGA): 8.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 4.6;Gastric cancer: 3.3" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Stomach - Gastric mucous cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA043523, HPA061125" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 77: Intestine - Digestion" "Cluster 15: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 88: Proximal tubular cells - Transmembrane transport" 2 "Nucleoplasm, Cytosol" "HPA043523: , HPA061125: " "unprognostic (1.26e-1)" "unprognostic (5.04e-2)" "validated prognostic favorable (1.83e-9)" "validated prognostic favorable (4.20e-5)" "unprognostic (3.35e-3)" "unprognostic (2.08e-1)" "unprognostic (3.76e-2)" "unprognostic (1.13e-1)" "unprognostic (1.95e-2)" "unprognostic (1.73e-3)" "unprognostic (5.06e-3)" "unprognostic (2.62e-1)" "unprognostic (1.38e-1)" ANKS6 "ANKRD14, FLJ36928, NPHP16, SAMD6" ENSG00000165138 "Ankyrin repeat and sterile alpha motif domain containing 6" Q68DC2 9 98731329-98796965 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant, Joubert syndrome, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 67.2;Brain excitatory neurons: 73.2;Oligodendrocytes: 65.6;Retinal ganglion cells: 69.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA008355 Approved Approved "Nucleoli fibrillar center,Primary cilium,Cytosol" NA NA "Cluster 64: Non-specific - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 33 "Nucleoli fibrillar center, Primary cilium" Cytosol "HPA008355: " "unprognostic (7.40e-2)" "unprognostic (1.11e-1)" "unprognostic (3.19e-2)" "unprognostic (7.84e-2)" "unprognostic (1.28e-1)" "unprognostic (1.98e-1)" "unprognostic (1.12e-1)" "unprognostic (5.82e-3)" "unprognostic (8.40e-2)" "unprognostic (4.53e-2)" "potential prognostic favorable (1.80e-6)" "unprognostic (1.04e-3)" "unprognostic (3.43e-1)" "unprognostic (5.21e-3)" "unprognostic (4.65e-2)" "unprognostic (7.47e-2)" "unprognostic (2.30e-1)" "unprognostic (2.99e-2)" "unprognostic (1.60e-2)" "unprognostic (2.06e-3)" "unprognostic (3.01e-1)" "unprognostic (3.82e-2)" "unprognostic (2.63e-1)" "unprognostic (4.99e-3)" "unprognostic (2.36e-1)" "unprognostic (2.19e-1)" "unprognostic (2.08e-1)" "unprognostic (3.45e-1)" "unprognostic (3.11e-1)" "unprognostic (2.27e-2)" "unprognostic (7.25e-2)" ANKUB1 C3orf16 ENSG00000206199 "Ankyrin repeat and ubiquitin domain containing 1" A6NFN9 3 149761100-149968385 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "choroid plexus: 3.1;fallopian tube: 5.6" "Cell type enhanced" "Detected in many" "Adipocytes: 367.0;Cardiomyocytes: 702.9;Early spermatids: 480.0;Endometrial ciliated cells: 425.5;Epicardial cells: 595.8;Fibro-adipogenic progenitors: 351.7;Myonuclei: 469.7;Respiratory ciliated cells: 450.4;Retinal ganglion cells: 305.2" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "neutrophil: 1.5" "Lineage enriched" "Detected in single" 13 "granulocytes: 1.5" "Cancer enhanced" "Detected in some" "Bile duct cancer: 1.6" "Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary gland ductal cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA053749 Uncertain NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "HPA053749: " "unprognostic (1.17e-1)" ANKZF1 "FLJ10415, Vms1, ZNF744" ENSG00000163516 "Ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1" Q9H8Y5 2 219229783-219236679 "Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035208 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 64: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 7: Non-specific - Transcription" 13 Nucleoplasm "Nuclear bodies, Cytosol" "HPA035208: " "unprognostic (5.26e-2)" "unprognostic (2.56e-2)" "unprognostic (1.20e-1)" "unprognostic (6.74e-3)" "unprognostic (6.72e-2)" "unprognostic (2.76e-1)" "unprognostic (1.06e-1)" "unprognostic (1.16e-2)" "unprognostic (7.88e-2)" "unprognostic (3.42e-2)" "unprognostic (3.47e-3)" "unprognostic (7.33e-2)" "unprognostic (4.79e-2)" "potential prognostic unfavorable (1.39e-4)" "unprognostic (4.16e-2)" "unprognostic (2.04e-2)" "unprognostic (7.32e-3)" "unprognostic (6.69e-3)" "unprognostic (1.17e-2)" "unprognostic (8.60e-3)" "unprognostic (6.28e-2)" "unprognostic (8.30e-2)" "unprognostic (1.52e-3)" "unprognostic (1.20e-3)" "unprognostic (1.12e-1)" "unprognostic (2.33e-1)" "unprognostic (1.35e-2)" "unprognostic (4.67e-3)" "unprognostic (7.95e-3)" "unprognostic (3.34e-1)" "unprognostic (4.76e-2)" ANLN "ANILLIN, scra, Scraps" ENSG00000011426 "Anillin, actin binding protein" Q9NQW6 7 36389821-36453791 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 163.3" "Cell type enhanced" "Detected in many" "Early spermatids: 185.0;Erythrocyte progenitors: 91.7;Gastric progenitor cells: 74.3;Late primary spermatocytes: 95.5;Monocyte progenitors: 259.4;Neutrophil progenitors: 134.9;Oligodendrocytes: 484.2" "Cell type enriched" "Detected in all" 6 "oligodendrocyte: 798.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005680, CAB033902, HPA050556, CAB062547, CAB068175" Enhanced Supported Nucleoplasm,Midbody Yes Yes "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 571 Nucleoplasm Midbody "CAB033902: , CAB062547: , CAB068175: , HPA005680: , HPA050556: " "unprognostic (1.17e-2)" "unprognostic (1.82e-2)" "unprognostic (2.26e-1)" "potential prognostic unfavorable (1.47e-4)" "unprognostic (1.98e-1)" "unprognostic (1.40e-2)" "unprognostic (1.39e-2)" "unprognostic (1.48e-1)" "unprognostic (1.06e-1)" "potential prognostic unfavorable (6.88e-4)" "validated prognostic unfavorable (1.38e-4)" "validated prognostic unfavorable (2.73e-6)" "potential prognostic unfavorable (2.05e-10)" "validated prognostic unfavorable (6.50e-6)" "validated prognostic unfavorable (8.72e-10)" "validated prognostic unfavorable (4.21e-7)" "validated prognostic unfavorable (1.34e-4)" "unprognostic (1.34e-1)" "unprognostic (8.27e-2)" "unprognostic (3.07e-1)" "unprognostic (2.48e-1)" "validated prognostic unfavorable (5.53e-6)" "validated prognostic unfavorable (1.76e-5)" "unprognostic (2.05e-2)" "unprognostic (2.00e-1)" "unprognostic (1.98e-2)" "unprognostic (3.06e-2)" "unprognostic (1.40e-2)" "unprognostic (2.71e-1)" "unprognostic (6.10e-2)" "unprognostic (4.69e-2)" ANO1 "DOG1, FLJ10261, ORAOV2, TAOS2, TMEM16A" ENSG00000131620 "Anoctamin 1" Q5XXA6 11 69985907-70189530 "Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Developmental protein, Ion channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 81.3;seminal vesicle: 83.9" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 243.7;Early spermatids: 195.2;Epididymal efferent duct absorptive cells: 362.8;Epididymal efferent duct ciliated cells: 101.6;Epididymal principal cells: 229.9;Foveolar cells: 164.3;Hepatocytes: 411.8;Lacrimal acinar cells: 175.7;Late spermatids: 197.4;Pericytes: 153.0;Salivary acinar cells: 215.1;Salivary myoepithelial cells: 102.4" "Cell type enhanced" "Detected in some" "LAMP5-LHX6 and Chandelier: 79.2;vascular associated smooth muscle cell: 45.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Esophageal cancer: 62.2;pancreatic cancer: 72.4" "Breast - Breast myoepithelial cells, Kidney - Fibroblasts, Liver - Hepatocytes, Lung - Fibroblasts_1, Pituitary gland - Fibroblasts, Testis - Late spermatids" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 8.8" "HPA032148, HPA057356" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 110: Mural cells - ECM organization" 5 "Plasma membrane" Nucleoplasm "HPA032148: , HPA057356: " "unprognostic (1.13e-1)" "unprognostic (2.70e-1)" "unprognostic (3.35e-1)" "unprognostic (5.07e-2)" "unprognostic (2.41e-2)" "unprognostic (4.50e-3)" "unprognostic (1.60e-1)" "unprognostic (3.32e-1)" "potential prognostic unfavorable (6.93e-5)" "unprognostic (9.17e-2)" "unprognostic (8.82e-2)" "potential prognostic favorable (2.19e-4)" "potential prognostic unfavorable (2.26e-5)" "unprognostic (2.09e-3)" "potential prognostic favorable (4.08e-6)" "unprognostic (3.70e-3)" "potential prognostic unfavorable (6.93e-4)" "unprognostic (2.07e-2)" "potential prognostic unfavorable (8.69e-5)" "unprognostic (9.53e-2)" "unprognostic (1.17e-2)" "potential prognostic unfavorable (6.07e-5)" "unprognostic (1.33e-2)" "unprognostic (1.43e-1)" "unprognostic (8.19e-2)" "unprognostic (1.35e-1)" "unprognostic (3.84e-2)" "unprognostic (1.73e-1)" "unprognostic (7.55e-2)" "unprognostic (1.46e-2)" "unprognostic (4.22e-2)" ANO10 "FLJ10375, MGC47890, SCAR10, TMEM16K" ENSG00000160746 "Anoctamin 10" Q9NW15 3 43354859-43691594 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 715.2;Neutrophils: 371.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Fibroblasts_1, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016624, HPA051569" Approved Supported "Vesicles,Plasma membrane,Primary cilium" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 77: Intestine - Digestion" "Cluster 25: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 1 "Plasma membrane" "Vesicles, Primary cilium" "HPA016624: , HPA051569: " "unprognostic (2.10e-3)" "unprognostic (2.67e-3)" "unprognostic (1.23e-1)" "unprognostic (1.83e-2)" "unprognostic (5.86e-3)" "unprognostic (2.63e-1)" "unprognostic (1.00e-1)" "unprognostic (3.09e-1)" "unprognostic (1.56e-1)" "unprognostic (5.56e-2)" "unprognostic (4.39e-3)" "unprognostic (5.60e-2)" "potential prognostic favorable (1.31e-4)" "potential prognostic unfavorable (1.88e-5)" "unprognostic (2.63e-1)" "unprognostic (2.51e-2)" "unprognostic (1.62e-2)" "unprognostic (7.20e-2)" "unprognostic (1.61e-1)" "unprognostic (6.24e-2)" "unprognostic (1.69e-2)" "unprognostic (8.38e-2)" "unprognostic (1.03e-1)" "unprognostic (2.13e-1)" "unprognostic (2.65e-1)" "unprognostic (1.60e-1)" "unprognostic (2.33e-2)" "unprognostic (4.87e-2)" "unprognostic (2.38e-1)" "unprognostic (1.26e-2)" "unprognostic (1.97e-2)" ANO2 "C12orf3, TMEM16B" ENSG00000047617 "Anoctamin 2" Q9NQ90 12 5531869-5946232 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 22 "retina: 190.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 1062.0;Late spermatids: 547.2;Rod photoreceptor cells: 2368.4;Vascular endothelial cells: 819.0" "Cell type enriched" "Detected in many" 4 "endothelial cell: 1260.0" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 8.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "basophil: 1.3" "Lineage enriched" "Detected in single" 13 "granulocytes: 1.3" "Cancer enhanced" "Detected in many" "cervical cancer: 7.6" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Minor Salivary Gland - Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells, Testis - Late spermatids" "Region enriched" "Detected in many" 4 "basal ganglia: 19.6" "HPA036276, HPA057499" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 42: Retina - Visual perception" "Cluster 47: Endothelial cells - Vasculature" "Cluster 1: Neuronal - Visual perception" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" "Plasma membrane" Nucleoplasm "HPA036276: , HPA057499: " "unprognostic (1.67e-1)" "unprognostic (4.05e-1)" "unprognostic (1.25e-1)" "unprognostic (1.85e-1)" "unprognostic (2.72e-2)" "potential prognostic favorable (3.64e-4)" "unprognostic (1.19e-1)" "unprognostic (2.84e-1)" "unprognostic (9.12e-2)" "unprognostic (2.36e-1)" "unprognostic (2.20e-1)" "unprognostic (1.73e-1)" ANO3 "C11orf25, DYT23, GENX-3947, TMEM16C" ENSG00000134343 "Anoctamin 3" Q9BYT9 11 26188842-26663289 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Disease variant, Dystonia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 20 "brain: 58.4;epididymis: 54.2" "Cell type enhanced" "Detected in many" "Adipocytes: 199.1;Brain excitatory neurons: 165.4;Brain inhibitory neurons: 405.4;Cone photoreceptor cells: 70.4;Epididymal principal cells: 202.3;Gonadotrophs: 61.3;Hepatic stellate cells: 284.0;Oligodendrocyte progenitor cells: 65.3;Pericytes: 96.4" "Cell type enhanced" "Detected in many" "medium spiny neuron: 1104.8" "Cancer enhanced" "Detected in single" "Kidney Renal Clear Cell Carcinoma (TCGA): 1.2" "Region enriched" "Detected in all" 5 "basal ganglia: 129.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 12 "Rhabdoid: 8.3" "Testis - Early spermatids" "Region enhanced" "Detected in all" "basal ganglia: 158.9" "Region enriched" "Detected in all" 7 "basal ganglia: 211.0" "HPA041629, CAB080586" Uncertain Supported "Microtubules,Mitotic spindle,Primary cilium,Basal body,Cytosol" Yes NA "Cluster 22: Epididymis - Mixed function" "Cluster 33: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" "Microtubules, Primary cilium, Cytosol" "Mitotic spindle, Basal body" "CAB080586: , HPA041629: " "unprognostic (3.04e-2)" "validated prognostic favorable (9.03e-8)" "validated prognostic favorable (4.02e-6)" ANO4 "FLJ34221, FLJ34272, FLJ35277, TMEM16D" ENSG00000151572 "Anoctamin 4" Q32M45 12 100717526-101128641 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 11.3;cervix: 7.2;seminal vesicle: 7.6" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 132.5;Adrenal medulla cells: 489.3;Brain excitatory neurons: 141.9;Brain inhibitory neurons: 289.2;Epididymal clear cells: 226.6;Oligodendrocyte progenitor cells: 452.7;Oligodendrocytes: 940.7;Other brain neurons: 222.0;Retinal ganglion cells: 251.1;Salivary ionocytes: 178.4;Somatotrophs: 172.7;Thyrotrophs: 204.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Kidney Chromophobe (TCGA): 7.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 4.8;testis cancer: 7.0" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary gland ductal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053412 Uncertain NA NA "Cluster 65: Brain - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 80: Oligodendrocytes - Myelination" 3 "HPA053412: " "unprognostic (2.31e-3)" "unprognostic (1.71e-1)" "unprognostic (1.67e-1)" "potential prognostic favorable (3.30e-4)" "unprognostic (2.40e-2)" "unprognostic (6.09e-2)" "unprognostic (5.52e-2)" ANO5 "GDD1, LGMD2L, TMEM16E" ENSG00000171714 "Anoctamin 5" Q75V66 11 21782659-22283567 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant, Limb-girdle muscular dystrophy, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "heart muscle: 22.7;parathyroid gland: 16.2;skeletal muscle: 61.5;tongue: 46.5" "Group enriched" "Detected in many" 4 "Cardiomyocytes: 469.5;Myonuclei: 1192.1" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in some" 5 "Kidney Chromophobe (TCGA): 7.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 4.4" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA058857 Uncertain NA NA "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 11: Neuronal - Sensory perception" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" "HPA058857: " "unprognostic (3.00e-2)" "unprognostic (6.37e-2)" "unprognostic (3.90e-2)" "unprognostic (2.00e-1)" "unprognostic (5.75e-2)" "unprognostic (9.31e-2)" "unprognostic (5.90e-2)" "unprognostic (5.13e-1)" "potential prognostic favorable (3.85e-4)" "unprognostic (4.83e-1)" "unprognostic (2.66e-2)" "unprognostic (1.19e-1)" "unprognostic (5.19e-3)" ANO6 "DKFZp313M0720, TMEM16F" ENSG00000177119 "Anoctamin 6" Q4KMQ2 12 45215987-45482280 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Host-virus interaction, Ion transport, Lipid transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 912.9;Myonuclei: 612.6;Platelets: 1145.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038958 Approved Approved "Plasma membrane,Cytosol" NA NA 41000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 75: Ovary - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 89: Adipocytes - Lipid metabolism" 16 "Plasma membrane, Cytosol" "HPA038958: " "unprognostic (1.31e-2)" "potential prognostic unfavorable (7.82e-5)" "unprognostic (3.28e-1)" "potential prognostic unfavorable (3.96e-4)" "unprognostic (1.77e-1)" "unprognostic (1.90e-2)" "unprognostic (4.44e-1)" "unprognostic (5.54e-2)" "unprognostic (2.50e-2)" "unprognostic (3.18e-1)" "potential prognostic favorable (2.41e-4)" "unprognostic (2.41e-2)" "unprognostic (1.37e-1)" "unprognostic (1.79e-2)" "unprognostic (1.48e-1)" "unprognostic (1.23e-2)" "unprognostic (2.44e-3)" "unprognostic (1.25e-3)" "potential prognostic unfavorable (5.93e-4)" "unprognostic (1.06e-3)" "unprognostic (3.96e-1)" "unprognostic (2.69e-3)" "unprognostic (1.90e-1)" "unprognostic (2.63e-1)" "unprognostic (8.28e-2)" "unprognostic (2.89e-1)" "unprognostic (1.15e-1)" "unprognostic (1.32e-2)" "unprognostic (6.46e-2)" "unprognostic (1.91e-1)" "potential prognostic unfavorable (7.54e-4)" ANO7 "IPCA-5, NGEP, PCANAP5, PCANAP5L, TMEM16G" ENSG00000146205 "Anoctamin 7" Q6IWH7 2 241188509-241225976 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "intestine: 18.0;prostate: 66.6;stomach 1: 26.9" "Cell type enhanced" "Detected in many" "Epicardial cells: 22.7;Epididymal principal cells: 27.8;Foveolar cells: 84.6;Goblet cells: 125.3;Oocytes: 32.2;Prostatic glandular cells: 145.0;Tuft cells: 69.2" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in many" 22 "Prostate Adenocarcinoma (TCGA): 65.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 6.6" "Colon - Colon enterocytes, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" HPA078464 Enhanced NA NA "Cluster 17: Intestine - Digestion" "Cluster 11: White matter - Signal transduction" "Cluster 24: Non-specific - Unknown function" "Cluster 70: Intestinal goblet cells - Mucin production" "HPA078464: " "unprognostic (7.13e-2)" "potential prognostic favorable (9.25e-4)" "unprognostic (3.81e-3)" "unprognostic (1.49e-2)" "unprognostic (3.96e-3)" "unprognostic (1.12e-1)" "unprognostic (1.55e-1)" "unprognostic (1.63e-1)" "unprognostic (6.57e-2)" "unprognostic (8.01e-2)" "unprognostic (4.29e-3)" "unprognostic (2.40e-3)" "unprognostic (3.97e-2)" "unprognostic (3.37e-3)" ANO8 "KIAA1623, TMEM16H" ENSG00000074855 "Anoctamin 8" Q9HCE9 19 17323223-17334855 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 26.8" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 29.9;Astrocytes: 111.1;Bergmann glia: 43.3;Breast lactating cells: 43.5;Ependymal cells: 24.8;Esophageal apical cells: 46.5" "Cell type enhanced" "Detected in all" "astrocyte: 118.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Prostate - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049206 Uncertain NA NA "Cluster 2: Non-specific - Mixed function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 23: Non-specific - Transcription" "Cluster 28: Astrocytes - Homeostasis & neuron support" "HPA049206: " "unprognostic (2.60e-2)" "unprognostic (8.56e-2)" "unprognostic (1.58e-2)" "unprognostic (2.03e-1)" "unprognostic (3.53e-2)" "unprognostic (1.50e-1)" "unprognostic (2.02e-1)" "unprognostic (2.90e-2)" "potential prognostic favorable (3.30e-4)" "unprognostic (7.20e-2)" "unprognostic (2.01e-1)" "unprognostic (1.36e-1)" "unprognostic (3.42e-2)" "unprognostic (1.92e-1)" "unprognostic (1.84e-2)" "unprognostic (7.76e-2)" "unprognostic (2.21e-1)" "unprognostic (1.71e-1)" "unprognostic (2.60e-3)" "unprognostic (2.16e-1)" "unprognostic (4.53e-2)" "unprognostic (2.13e-1)" "unprognostic (5.31e-3)" "unprognostic (1.21e-1)" "unprognostic (4.51e-2)" "unprognostic (1.59e-1)" "unprognostic (7.31e-2)" "unprognostic (4.45e-2)" "unprognostic (6.51e-2)" "unprognostic (6.14e-3)" "unprognostic (1.50e-1)" ANO9 "PIG5, TMEM16J, TP53I5" ENSG00000185101 "Anoctamin 9" A1A5B4 11 417933-442011 "Predicted membrane proteins, Transporters" "Lipid metabolism, Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 32.2;skin 1: 26.3" "Cell type enhanced" "Detected in many" "Colonocytes: 82.2;Enteric stem cells: 49.2;Enteric transient amplifying cells: 52.5;Enterocytes: 109.8;Epididymal principal cells: 34.6;Goblet cells: 77.1;Paneth cells: 65.7;Proximal tubule cells: 34.2" "Cell type enriched" "Detected in single" 19 "leukocyte: 19.2" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 26.2;Rectum Adenocarcinoma (TCGA): 25.4" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 48 "B-cells: 2.1;NK-cells: 4.1;T-cells: 8.3" "Cancer enhanced" "Detected in many" "colorectal cancer: 16.4" "Adipose subcutaneous - T-cells, Adrenal gland - T-cells, Liver - T-cells, Stomach - Gastric mucous cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA039948, HPA040112" Approved Uncertain "Golgi apparatus" NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 2 "Golgi apparatus" "HPA039948: , HPA040112: " "unprognostic (1.31e-3)" "unprognostic (3.25e-1)" "unprognostic (7.83e-2)" "unprognostic (5.61e-2)" "unprognostic (2.03e-1)" "unprognostic (1.05e-2)" "unprognostic (1.42e-1)" "unprognostic (3.71e-1)" "potential prognostic favorable (1.64e-4)" "unprognostic (2.75e-1)" "unprognostic (1.99e-1)" "unprognostic (1.19e-1)" "unprognostic (2.76e-2)" "unprognostic (3.35e-1)" "unprognostic (1.43e-1)" "unprognostic (2.33e-1)" "unprognostic (1.41e-3)" "unprognostic (1.40e-1)" "unprognostic (1.75e-2)" "unprognostic (2.16e-3)" "unprognostic (1.18e-1)" "unprognostic (2.46e-3)" "unprognostic (1.09e-1)" "unprognostic (1.66e-1)" "unprognostic (1.55e-2)" "unprognostic (9.72e-2)" "unprognostic (3.21e-2)" "unprognostic (1.85e-2)" ANOS1 "ADMLX, KAL, KAL1, KALIG-1, WFDC19" ENSG00000011201 "Anosmin 1" P23352 X 8528874-8732137 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Cell adhesion, Chemotaxis" "Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 40.7" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 95.7;Alveolar cells type 1: 339.9;Astrocytes: 154.5;Fibro-adipogenic progenitors: 105.8;Medullary thymic epithelial cells: 206.4;Microglia: 186.8;Prostatic glandular cells: 87.5;Respiratory basal cells: 288.2;Sertoli cells: 120.2" "Cell type enhanced" "Detected in many" "astrocyte: 259.9;central nervous system macrophage: 234.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 15.1" "Adipose visceral - Mesothelial cells, Colon - Enteric glia cells, Lung - Alveolar cells type 1, Prostate - Prostate glandular cells, Skin - Outer root sheath cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Secreted in brain" "Cell adhesion" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 22: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 5 "unprognostic (5.70e-2)" "unprognostic (4.00e-1)" "unprognostic (7.67e-2)" "unprognostic (9.46e-2)" "unprognostic (2.37e-1)" "unprognostic (1.08e-1)" "unprognostic (2.30e-2)" "unprognostic (6.79e-2)" "unprognostic (2.27e-1)" "potential prognostic favorable (7.12e-5)" "unprognostic (8.70e-3)" "unprognostic (4.29e-2)" "unprognostic (3.63e-3)" "unprognostic (6.45e-2)" "unprognostic (4.58e-2)" "unprognostic (2.31e-2)" "unprognostic (6.08e-2)" "unprognostic (8.25e-2)" "unprognostic (3.43e-2)" "unprognostic (7.14e-2)" "unprognostic (9.78e-2)" "unprognostic (1.21e-1)" "unprognostic (4.46e-2)" "unprognostic (2.78e-3)" "unprognostic (3.23e-3)" "unprognostic (1.37e-1)" "unprognostic (2.31e-2)" "unprognostic (2.20e-1)" ANP32A "C15orf1, I1PP2A, LANP, MAPM, mapmodulin, PHAPI, PP32" ENSG00000140350 "Acidic nuclear phosphoprotein 32 family member A" P39687 15 68778535-68820897 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 483.7;Neutrophils: 1468.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005231, HPA063133, HPA067561" Supported Supported Nucleoplasm,Centrosome,Cytosol NA NA 2300000 "Cluster 29: Non-specific - Unknown function" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 27 Nucleoplasm "Centrosome, Cytosol" "CAB005231: , HPA063133: , HPA067561: " "unprognostic (4.45e-3)" "unprognostic (1.38e-1)" "unprognostic (7.74e-2)" "unprognostic (1.74e-2)" "unprognostic (3.05e-2)" "unprognostic (1.83e-2)" "unprognostic (6.36e-2)" "unprognostic (5.91e-3)" "unprognostic (2.34e-2)" "unprognostic (7.67e-2)" "unprognostic (1.63e-3)" "unprognostic (7.49e-2)" "unprognostic (4.60e-2)" "unprognostic (1.77e-3)" "potential prognostic unfavorable (9.66e-5)" "unprognostic (8.28e-3)" "unprognostic (3.65e-3)" "unprognostic (1.63e-1)" "unprognostic (6.03e-2)" "unprognostic (1.39e-1)" "unprognostic (4.25e-1)" "unprognostic (4.03e-3)" "unprognostic (1.45e-1)" "unprognostic (2.00e-1)" "unprognostic (5.73e-3)" "unprognostic (1.39e-1)" "unprognostic (1.88e-1)" "unprognostic (7.59e-2)" "unprognostic (1.77e-1)" "unprognostic (2.77e-2)" "unprognostic (2.71e-1)" ANP32B "APRIL, PHAPI2, SSP29" ENSG00000136938 "Acidic nuclear phosphoprotein 32 family member B" Q92688 9 97983341-98015943 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythrocyte progenitors: 854.5;Megakaryocyte progenitors: 893.1;Megakaryocytes: 902.5;Monocyte progenitors: 700.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063133, HPA067561, HPA069657" Supported Supported Nucleoplasm,Centrosome,Cytosol NA NA 1800000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 6: Non-specific - Immune response" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Cell proliferation" 36 Nucleoplasm "Centrosome, Cytosol" "HPA063133: , HPA067561: , HPA069657: " "unprognostic (1.07e-2)" "unprognostic (1.85e-1)" "unprognostic (2.36e-1)" "unprognostic (5.56e-2)" "unprognostic (5.81e-2)" "unprognostic (5.29e-2)" "unprognostic (8.53e-2)" "unprognostic (5.01e-2)" "unprognostic (9.63e-3)" "unprognostic (1.15e-1)" "potential prognostic favorable (5.17e-4)" "unprognostic (6.58e-3)" "unprognostic (1.45e-2)" "validated prognostic unfavorable (7.14e-8)" "validated prognostic unfavorable (1.11e-6)" "potential prognostic unfavorable (1.34e-6)" "unprognostic (3.59e-3)" "unprognostic (6.89e-2)" "unprognostic (9.62e-2)" "unprognostic (3.38e-1)" "unprognostic (2.51e-1)" "unprognostic (8.20e-2)" "unprognostic (3.07e-2)" "unprognostic (3.85e-2)" "unprognostic (9.26e-2)" "unprognostic (5.81e-2)" "unprognostic (9.82e-2)" "unprognostic (3.53e-1)" "unprognostic (1.11e-1)" "unprognostic (2.27e-1)" "potential prognostic favorable (7.53e-5)" ANP32D PP32R2 ENSG00000139223 "Acidic nuclear phosphoprotein 32 family member D" O95626 12 48472559-48473622 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA063133, HPA067561" Uncertain Approved Nucleoplasm,Centrosome NA NA "Cluster 24: Neurons - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" Nucleoplasm Centrosome "HPA063133: , HPA067561: " ANP32E "LANP-L, LANPL, MGC5350" ENSG00000143401 "Acidic nuclear phosphoprotein 32 family member E" Q9BTT0 1 150218417-150236156 "Predicted intracellular proteins" "Chaperone, Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Megakaryocyte progenitors: 202.1;Monocyte progenitors: 396.8;Neutrophil progenitors: 219.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB021114, HPA063133, HPA067561" Supported Approved Nucleoplasm,Centrosome,Cytosol NA NA 270000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 25: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 27: Non-specific - Cell proliferation" 45 Nucleoplasm "Centrosome, Cytosol" "CAB021114: , HPA063133: , HPA067561: " "unprognostic (5.83e-2)" "unprognostic (1.12e-1)" "unprognostic (1.12e-1)" "unprognostic (4.31e-3)" "unprognostic (6.51e-2)" "unprognostic (1.67e-1)" "unprognostic (3.24e-2)" "unprognostic (1.55e-1)" "unprognostic (1.00e-1)" "unprognostic (4.83e-2)" "potential prognostic favorable (5.48e-4)" "unprognostic (3.31e-3)" "unprognostic (8.25e-2)" "potential prognostic unfavorable (5.01e-5)" "unprognostic (1.22e-2)" "unprognostic (1.29e-3)" "unprognostic (2.70e-2)" "unprognostic (1.34e-3)" "unprognostic (3.74e-2)" "unprognostic (1.04e-1)" "unprognostic (7.49e-2)" "unprognostic (1.50e-2)" "unprognostic (2.03e-1)" "unprognostic (1.29e-1)" "unprognostic (1.02e-1)" "unprognostic (1.53e-1)" "unprognostic (4.27e-2)" "unprognostic (1.50e-2)" "unprognostic (1.50e-1)" "unprognostic (1.81e-2)" "unprognostic (3.66e-2)" ANPEP "AP-N, CD13, gp150, hAPN, LAP1, p150, PEPN" ENSG00000166825 "Alanyl aminopeptidase, membrane" P15144 15 89784895-89815401 "CD markers, Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Differentiation, Host-virus interaction" "Aminopeptidase, Developmental protein, Host cell receptor for virus entry, Hydrolase, Metalloprotease, Protease, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 2245.0;pancreas: 643.6" "Cell type enriched" "Detected in many" 9 "Enterocytes: 6494.6" "Cell type enriched" "Detected in some" 4 "pericyte: 83.6" "Cancer enhanced" "Detected in all" "Kidney Renal Papillary Cell Carcinoma (TCGA): 311.1" "Group enriched" "Detected in many" 5 "cerebral cortex: 19.2;thalamus: 38.8" "Immune cell enriched" "Detected in many" 4 "neutrophil: 227.8" "Lineage enriched" "Detected in many" 4 "granulocytes: 227.8" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 455.0" "Adipose visceral - Macrophages, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Skeletal muscle - Macrophages, Spleen - Neutrophils_2, Stomach - Macrophages" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 5 "spinal cord: 19.5" "CAB002417, HPA004625" Enhanced Supported "Plasma membrane" NA NA 420000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 77: Intestine - Digestion" "Cluster 12: Non-specific - Vasculature" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 1: Enterocytes - Absorption and Digestion" 15 "Plasma membrane" "CAB002417: , HPA004625: " "unprognostic (9.29e-2)" "unprognostic (3.34e-2)" "unprognostic (1.53e-2)" "unprognostic (1.16e-2)" "unprognostic (2.46e-2)" "unprognostic (2.82e-1)" "unprognostic (7.64e-2)" "unprognostic (1.54e-2)" "unprognostic (4.31e-1)" "unprognostic (1.97e-2)" "potential prognostic favorable (5.54e-7)" "unprognostic (1.25e-2)" "unprognostic (3.78e-3)" "unprognostic (2.63e-2)" "unprognostic (1.56e-1)" "unprognostic (2.45e-1)" "potential prognostic unfavorable (4.98e-4)" "unprognostic (7.80e-3)" "unprognostic (4.92e-2)" "unprognostic (7.48e-2)" "unprognostic (3.83e-1)" "unprognostic (7.37e-3)" "unprognostic (7.63e-2)" "unprognostic (4.32e-1)" "unprognostic (1.49e-1)" "unprognostic (6.25e-2)" "unprognostic (1.35e-1)" "unprognostic (2.58e-2)" "unprognostic (1.08e-2)" "unprognostic (3.55e-2)" "unprognostic (6.63e-2)" ANTKMT "C16orf24, FAM173A, MGC2494" ENSG00000103254 "Adenine nucleotide translocase lysine methyltransferase" Q9BQD7 16 720581-722590 "Predicted intracellular proteins, Predicted membrane proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 217.3;Late primary spermatocytes: 423.5;Late spermatids: 785.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046262 Approved Approved Cytosol NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 10 Cytosol "HPA046262: " "unprognostic (2.68e-1)" "unprognostic (4.34e-1)" "unprognostic (2.31e-2)" "unprognostic (5.09e-2)" "unprognostic (2.17e-1)" "unprognostic (8.61e-2)" "unprognostic (1.03e-1)" "unprognostic (5.56e-2)" "unprognostic (1.64e-1)" "unprognostic (7.39e-2)" "unprognostic (8.22e-3)" "unprognostic (6.64e-3)" "unprognostic (8.91e-2)" "unprognostic (8.61e-3)" "unprognostic (1.46e-1)" "unprognostic (2.73e-2)" "unprognostic (3.01e-1)" "unprognostic (6.01e-2)" "unprognostic (8.98e-2)" "unprognostic (7.19e-2)" "unprognostic (2.25e-1)" "unprognostic (4.99e-2)" "unprognostic (2.79e-1)" "unprognostic (2.20e-1)" "unprognostic (3.02e-1)" "unprognostic (1.27e-1)" "unprognostic (2.62e-1)" "unprognostic (6.25e-2)" "unprognostic (1.93e-1)" ANTXR1 "ATR, FLJ10601, FLJ21776, TEM8" ENSG00000169604 "ANTXR cell adhesion molecule 1" Q9H6X2 2 69013176-69249327 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor Hypotrichosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 205.1" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 441.2;Bergmann glia: 338.2;Choroid plexus epithelial cells: 778.7;Endometrial stromal cells: 326.0;Ependymal cells: 335.1;Fibro-adipogenic progenitors: 276.6;Myosatellite cells: 391.5;Salivary myoepithelial cells: 409.9;Thymic myoid cells: 538.4;Thyrotrophs: 288.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 349.2" "Adrenal gland - Adrenal cortex cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Spleen - Fibroblasts_1, Testis - Peritubular cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054785 Uncertain Vesicles "Intracellular and membrane" Receptor NA NA 5400000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 29 Vesicles "HPA054785: " "unprognostic (1.71e-2)" "unprognostic (2.12e-1)" "unprognostic (9.37e-3)" "unprognostic (2.00e-3)" "unprognostic (3.27e-2)" "unprognostic (1.35e-1)" "unprognostic (1.45e-1)" "unprognostic (1.27e-2)" "unprognostic (4.96e-2)" "unprognostic (9.30e-2)" "unprognostic (1.44e-2)" "unprognostic (3.63e-3)" "unprognostic (6.07e-2)" "unprognostic (6.86e-2)" "unprognostic (1.79e-1)" "unprognostic (2.21e-1)" "unprognostic (4.66e-2)" "unprognostic (6.37e-2)" "unprognostic (2.05e-1)" "unprognostic (1.33e-3)" "potential prognostic unfavorable (1.07e-4)" "unprognostic (2.84e-2)" "unprognostic (1.29e-1)" "unprognostic (1.49e-1)" "unprognostic (2.53e-1)" "unprognostic (5.35e-3)" "unprognostic (2.76e-2)" "potential prognostic unfavorable (2.26e-4)" "unprognostic (7.66e-2)" "potential prognostic unfavorable (1.48e-4)" "unprognostic (7.33e-2)" ANTXR2 "CMG-2, CMG2, FLJ31074" ENSG00000163297 "ANTXR cell adhesion molecule 2" P58335 4 79901146-80125454 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 291.9;Fibro-adipogenic progenitors: 396.2;monocytes: 386.2;Neutrophil progenitors: 1005.4;Neutrophils: 1150.9;Prostatic glandular cells: 604.3" "Cell type enhanced" "Detected in many" "ependymal cell: 232.6;fibroblast: 431.8;leukocyte: 210.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Kidney - Fibroblasts, Minor Salivary Gland - Macrophages, Pituitary gland - Fibroblasts, Spleen - Fibroblasts_1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "Intracellular and membrane" Receptor NA NA 5600000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 75: Ovary - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 2 "unprognostic (2.44e-2)" "unprognostic (1.63e-1)" "unprognostic (9.07e-3)" "unprognostic (1.98e-2)" "unprognostic (1.54e-2)" "unprognostic (2.24e-1)" "unprognostic (9.73e-2)" "unprognostic (2.14e-2)" "unprognostic (8.81e-3)" "unprognostic (3.83e-2)" "validated prognostic favorable (1.28e-6)" "validated prognostic favorable (3.54e-4)" "unprognostic (2.37e-1)" "unprognostic (6.32e-2)" "unprognostic (5.86e-2)" "unprognostic (5.49e-3)" "unprognostic (1.42e-3)" "unprognostic (9.44e-3)" "unprognostic (2.15e-2)" "unprognostic (6.39e-3)" "unprognostic (1.38e-3)" "unprognostic (1.50e-3)" "unprognostic (3.16e-1)" "unprognostic (1.02e-1)" "unprognostic (2.35e-2)" "unprognostic (1.39e-1)" "unprognostic (8.38e-2)" "unprognostic (4.63e-3)" "unprognostic (1.51e-1)" "unprognostic (3.64e-2)" "unprognostic (2.47e-1)" ANTXRL ENSG00000274209 "ANTXR like" A6NF34 10 46286345-46330207 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 13 "testis: 12.0" "Group enriched" "Detected in some" 8 "Early spermatids: 70.6;Late primary spermatocytes: 41.2;Late spermatids: 50.1;Sertoli cells: 20.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "neutrophil: 1.1" "Lineage enriched" "Detected in single" 8 "granulocytes: 1.1" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 57: Testis - Spermatogenesis" "Cluster 70: DU4475 - Unknown function" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" ANXA1 "ANX1, LPC1" ENSG00000135046 "Annexin A1" P04083 9 73151865-73170393 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Adaptive immunity, Immunity, Inflammatory response, Innate immunity" "Phospholipase A2 inhibitor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 7699.2" "Cell type enriched" "Detected in many" 4 "Esophageal apical cells: 89658.7" "Group enriched" "Detected in many" 13 "endothelial cell: 140.6;ependymal cell: 259.6;fibroblast: 148.8;leukocyte: 226.5;vascular associated smooth muscle cell: 74.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 2824.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011271, HPA011272, CAB013023, CAB035987, CAB058693, CAB080415" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" Immunity NA Yes 17600000 24000000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 39: Astrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 35 "Plasma membrane, Cytosol" Nucleoplasm "CAB013023: , CAB035987: , CAB058693: , CAB080415: , HPA011271: , HPA011272: " "unprognostic (2.41e-3)" "unprognostic (9.20e-3)" "unprognostic (1.75e-1)" "unprognostic (1.32e-1)" "unprognostic (1.30e-1)" "unprognostic (6.39e-2)" "unprognostic (2.17e-2)" "unprognostic (5.11e-3)" "unprognostic (8.49e-2)" "unprognostic (4.02e-2)" "unprognostic (2.83e-2)" "unprognostic (2.00e-1)" "unprognostic (2.07e-1)" "unprognostic (2.02e-2)" "unprognostic (1.28e-1)" "unprognostic (1.11e-2)" "unprognostic (3.05e-2)" "unprognostic (1.69e-1)" "unprognostic (1.17e-1)" "unprognostic (4.63e-2)" "unprognostic (1.64e-1)" "unprognostic (1.86e-3)" "unprognostic (3.66e-3)" "unprognostic (3.30e-1)" "unprognostic (1.30e-1)" "unprognostic (4.76e-3)" "unprognostic (1.51e-1)" "unprognostic (3.59e-2)" "unprognostic (4.87e-2)" "potential prognostic favorable (8.16e-4)" "unprognostic (2.84e-2)" ANXA10 ANX14 ENSG00000109511 "Annexin A10" Q9UJ72 4 168092537-168187736 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "stomach 1: 459.0" "Cell type enhanced" "Detected in some" "Foveolar cells: 1700.9;Gastric chief cells: 354.9;Gastric progenitor cells: 297.3;Mucous neck cells: 587.8;Pancreatic acinar cells: 185.3;Parietal cells: 705.4;Urothelial cells: 252.5" "Low cell type specificity" "Detected in some" "Group enriched" "Detected in many" 5 "Pancreatic Adenocarcinoma (TCGA): 114.2;Stomach Adenocarcinoma (TCGA): 70.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 72.6;Gastric cancer: 50.4;pancreatic cancer: 55.5" "Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA005469, HPA074650" Enhanced Approved Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 60: Stomach - Digestion" "Cluster 66: Non-specific - Mitochondria" "Cluster 68: Foveolar cells - Mucosal defense" 5 "Nucleoplasm, Nucleoli" Vesicles "HPA005469: , HPA074650: " "unprognostic (7.80e-2)" "unprognostic (2.03e-1)" "unprognostic (3.14e-1)" "unprognostic (1.55e-2)" "unprognostic (7.64e-2)" "potential prognostic favorable (3.86e-7)" "potential prognostic unfavorable (4.00e-5)" "unprognostic (1.98e-1)" "unprognostic (3.05e-1)" "unprognostic (3.79e-1)" "unprognostic (5.87e-2)" "unprognostic (4.68e-2)" "unprognostic (4.95e-2)" "unprognostic (1.84e-1)" "unprognostic (3.74e-2)" ANXA11 ANX11 ENSG00000122359 "Annexin A11" P50995 10 80150889-80205572 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division" "Amyotrophic lateral sclerosis, Cancer-related genes, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 2349.5;Urothelial cells: 812.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 445.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004851, HPA027545" Supported Supported Nucleoplasm,Vesicles,Cytosol NA NA 210000 "Cluster 21: Neutrophils - Unknown function" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 84: Apical squamous epithelium - Cornification" 18 Nucleoplasm "Vesicles, Cytosol" "CAB004851: , HPA027545: " "unprognostic (8.12e-3)" "unprognostic (1.20e-1)" "unprognostic (3.11e-1)" "unprognostic (1.21e-1)" "unprognostic (2.99e-1)" "unprognostic (1.38e-1)" "unprognostic (3.96e-2)" "unprognostic (1.35e-1)" "unprognostic (1.85e-2)" "unprognostic (4.05e-1)" "potential prognostic favorable (3.92e-5)" "unprognostic (2.16e-1)" "potential prognostic favorable (1.99e-6)" "unprognostic (1.43e-3)" "unprognostic (1.48e-1)" "unprognostic (8.33e-2)" "potential prognostic unfavorable (2.16e-4)" "potential prognostic unfavorable (3.27e-4)" "unprognostic (3.50e-3)" "unprognostic (1.21e-1)" "unprognostic (1.75e-1)" "unprognostic (7.07e-3)" "unprognostic (5.01e-1)" "unprognostic (1.66e-1)" "unprognostic (1.27e-2)" "unprognostic (2.00e-1)" "unprognostic (1.84e-1)" "unprognostic (6.62e-3)" "unprognostic (1.60e-1)" "unprognostic (1.20e-1)" "unprognostic (1.72e-1)" ANXA13 ANX13 ENSG00000104537 "Annexin A13" P27216 8 123680794-123737402 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 135.6;intestine: 275.9" "Cell type enhanced" "Detected in many" "Cholangiocytes: 160.6;Enteric transient amplifying cells: 66.9;Enterocytes: 128.6;Epididymal efferent duct ciliated cells: 164.5;Fallopian tube ciliated cells: 183.5;Gastric progenitor cells: 53.8;Goblet cells: 173.1;Paneth cells: 65.7;Rod photoreceptor cells: 71.9;Tuft cells: 484.2" "Cell type enhanced" "Detected in some" "oligodendrocyte: 5.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 18.8;Gastric cancer: 33.6;Kidney cancer: 22.6" "Lung - Respiratory ciliated cells, Pancreas - Ductal cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA018535, HPA019569, HPA019650, CAB025135" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 30: White matter - Myelination" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 95: Tuft cells - Chemosensory signaling" 1 "Plasma membrane" Nucleoplasm "CAB025135: , HPA018535: , HPA019569: , HPA019650: " "unprognostic (3.08e-2)" "unprognostic (1.54e-1)" "unprognostic (9.49e-2)" "potential prognostic favorable (1.29e-4)" "unprognostic (6.23e-3)" "unprognostic (1.56e-1)" "unprognostic (5.56e-2)" "unprognostic (1.48e-1)" "unprognostic (1.03e-3)" "unprognostic (1.84e-1)" "unprognostic (8.90e-2)" "unprognostic (2.91e-1)" "unprognostic (2.48e-1)" "unprognostic (1.77e-2)" "unprognostic (2.06e-2)" "unprognostic (1.13e-1)" "unprognostic (2.58e-2)" "unprognostic (6.59e-2)" "unprognostic (2.04e-1)" ANXA2 "ANX2, ANX2L4, CAL1H, LIP2, LPC2D" ENSG00000182718 "Annexin A2" P07355 15 60347134-60402883 "Cancer-related genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Host-virus interaction" RNA-binding "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 1962.5" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 13656.2;Esophageal suprabasal cells: 5849.2;Extravillous trophoblasts: 3720.9;Migrating cytotrophoblasts: 2842.7;Ocular epithelial cells: 3816.8;Suprabasal keratinocytes: 2907.1" "Cell type enhanced" "Detected in many" "ependymal cell: 101.5;fibroblast: 169.0;vascular associated smooth muscle cell: 96.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 4446.3;classical monocyte: 2767.4;intermediate monocyte: 2404.9;myeloid DC: 4023.2;non-classical monocyte: 2699.3;T-reg: 1686.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 213.0" "CAB004311, HPA046964, HPA061798" Enhanced Approved "Plasma membrane,Cytosol" "Secreted to blood" Other NA NA 26700000000 25000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 12: Non-specific - Vasculature" "Cluster 72: Neuronal - Signal transduction" "Cluster 100: Stratified epithelial cells - Barrier functions" 57 "Plasma membrane" Cytosol "CAB004311: , HPA046964: , HPA061798: " "unprognostic (3.58e-3)" "unprognostic (1.72e-2)" "unprognostic (1.04e-1)" "unprognostic (1.96e-1)" "unprognostic (1.53e-1)" "unprognostic (3.13e-2)" "unprognostic (1.89e-3)" "potential prognostic unfavorable (1.89e-4)" "unprognostic (1.41e-3)" "unprognostic (1.44e-2)" "potential prognostic unfavorable (4.91e-4)" "unprognostic (3.19e-2)" "unprognostic (5.16e-2)" "validated prognostic unfavorable (7.78e-4)" "validated prognostic unfavorable (5.03e-4)" "potential prognostic unfavorable (1.13e-4)" "unprognostic (1.89e-2)" "unprognostic (2.44e-2)" "unprognostic (2.35e-3)" "unprognostic (1.67e-2)" "unprognostic (4.36e-2)" "potential prognostic unfavorable (1.38e-5)" "unprognostic (9.67e-3)" "unprognostic (5.95e-2)" "unprognostic (2.33e-1)" "unprognostic (5.63e-2)" "unprognostic (3.03e-1)" "unprognostic (1.14e-1)" "unprognostic (9.57e-2)" "unprognostic (2.86e-2)" "unprognostic (8.85e-3)" ANXA2R "AXIIR, C5orf39" ENSG00000177721 "Annexin A2 receptor" Q3ZCQ2 5 43039233-43043170 "Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 18.7;lymphoid tissue: 24.4" "Cell type enhanced" "Detected in some" "NK-cells: 1.0;Podocytes: 1.3;T-cells: 1.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "gdT-cell: 54.1;MAIT T-cell: 63.6;memory B-cell: 34.5;memory CD4 T-cell: 56.3;memory CD8 T-cell: 59.9;naive B-cell: 33.0;naive CD4 T-cell: 96.6;naive CD8 T-cell: 72.3;NK-cell: 24.9;T-reg: 66.7" "Group enriched" "Detected in all" 6 "B-cells: 34.5;NK-cells: 24.9;T-cells: 96.6" "Cancer enriched" "Detected in many" 4 "Leukemia: 25.9" "Colon - Endothelial cells, Liver - T-cells, Thyroid gland - T-cells" HPA051482 Uncertain Approved "Nucleoplasm,Cytosol,Cytoplasmic bodies" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 11: White matter - Signal transduction" "Cluster 35: RS4;11 - Unknown function" "Cluster 105: Non-specific - Mixed function" 1 Nucleoplasm "Cytosol, Cytoplasmic bodies" "HPA051482: " "unprognostic (1.44e-1)" "unprognostic (8.66e-3)" "unprognostic (1.57e-1)" "unprognostic (6.91e-2)" "potential prognostic unfavorable (1.74e-4)" "unprognostic (6.94e-3)" "unprognostic (1.77e-2)" "unprognostic (7.21e-3)" "unprognostic (5.25e-2)" "unprognostic (3.12e-2)" "unprognostic (1.48e-1)" "unprognostic (2.01e-2)" "unprognostic (5.74e-3)" "unprognostic (6.18e-2)" "unprognostic (4.32e-2)" "unprognostic (2.81e-1)" "unprognostic (7.35e-2)" "unprognostic (1.93e-1)" "unprognostic (1.46e-2)" "unprognostic (7.66e-2)" "unprognostic (6.19e-3)" "unprognostic (3.84e-1)" "unprognostic (7.74e-2)" "unprognostic (3.38e-2)" "unprognostic (9.21e-2)" "unprognostic (2.11e-1)" "unprognostic (4.75e-2)" "unprognostic (9.80e-2)" "unprognostic (2.13e-2)" ANXA3 ANX3 ENSG00000138772 "Annexin A3" P12429 4 78551747-78610451 "FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Phospholipase A2 inhibitor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 319.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 816.7;Breast myoepithelial cells: 341.9;Esophageal apical cells: 750.9;Megakaryocytes: 463.6;Migrating cytotrophoblasts: 329.8;Neutrophil progenitors: 1295.8;Neutrophils: 784.3;Pancreatic duct cells: 370.7;Salivary duct cells: 301.8" "Cell type enriched" "Detected in many" 5 "endothelial cell: 341.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 328 "neutrophil: 208.7" "Lineage enriched" "Detected in single" 328 "granulocytes: 208.7" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 1, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Ductal cells, Prostate - Prostate glandular cells, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "HPA013398, HPA013431" Enhanced Supported "Plasma membrane" NA NA 5000000 "Cluster 4: Neutrophils - Degranulation" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 37: Neutrophil progenitors - Granulopoiesis" "Plasma membrane" "HPA013398: , HPA013431: " "unprognostic (3.22e-1)" "unprognostic (4.15e-1)" "unprognostic (1.09e-1)" "unprognostic (1.71e-2)" "unprognostic (2.26e-3)" "unprognostic (1.44e-1)" "unprognostic (3.50e-1)" "unprognostic (7.04e-3)" "unprognostic (4.83e-3)" "unprognostic (7.43e-2)" "unprognostic (1.32e-3)" "unprognostic (2.68e-2)" "unprognostic (8.09e-2)" "unprognostic (1.59e-2)" "unprognostic (1.01e-3)" "unprognostic (2.32e-1)" "unprognostic (4.47e-1)" "unprognostic (3.11e-2)" "unprognostic (2.14e-3)" "unprognostic (5.09e-3)" "unprognostic (3.34e-1)" "potential prognostic unfavorable (2.29e-4)" "unprognostic (4.35e-2)" "unprognostic (2.65e-1)" "unprognostic (7.54e-3)" "unprognostic (5.99e-2)" "unprognostic (1.83e-1)" "unprognostic (2.88e-1)" "unprognostic (2.24e-1)" "unprognostic (6.40e-2)" "unprognostic (2.71e-2)" ANXA4 ANX4 ENSG00000196975 "Annexin A4" P09525 2 69644425-69827112 "Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "gallbladder: 535.2;pancreas: 336.5" "Cell type enhanced" "Detected in all" "Cholangiocytes: 3206.1;Pancreatic duct cells: 2703.9;Syncytiotrophoblasts: 824.0" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 396.1" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 8 "choroid plexus: 85.6" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005076, HPA007393, CAB017560" Enhanced Approved Cytosol NA NA 820000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 60: Stomach - Digestion" "Cluster 36: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." 9 Cytosol "CAB005076: , CAB017560: , HPA007393: " "unprognostic (2.56e-1)" "unprognostic (7.69e-3)" "unprognostic (1.54e-1)" "unprognostic (4.11e-2)" "unprognostic (2.55e-1)" "unprognostic (1.18e-1)" "unprognostic (1.04e-3)" "unprognostic (1.70e-3)" "unprognostic (3.40e-1)" "unprognostic (5.00e-1)" "potential prognostic favorable (5.50e-6)" "unprognostic (7.73e-2)" "unprognostic (4.33e-3)" "unprognostic (2.53e-1)" "unprognostic (1.32e-1)" "unprognostic (1.93e-1)" "unprognostic (2.91e-2)" "unprognostic (3.87e-1)" "unprognostic (1.08e-1)" "potential prognostic unfavorable (3.47e-4)" "unprognostic (1.99e-2)" "unprognostic (2.27e-3)" "unprognostic (1.76e-1)" "unprognostic (1.95e-1)" "unprognostic (9.00e-2)" "unprognostic (6.02e-2)" "unprognostic (1.10e-1)" "unprognostic (6.39e-2)" "unprognostic (9.97e-2)" "unprognostic (7.21e-2)" "unprognostic (1.39e-1)" ANXA5 "ANX5, CPB-I, ENX2, PAP-I, RPRGL3, VAC-alph" ENSG00000164111 "Annexin A5" P08758 4 121667946-121696995 "Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Transporters" "Blood coagulation, Hemostasis" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 1348.3;Extravillous trophoblasts: 1407.8;Migrating cytotrophoblasts: 1188.4;monocytes: 891.1;Pancreatic duct cells: 1031.2;Syncytiotrophoblasts: 1283.6" "Cell type enhanced" "Detected in many" "fibroblast: 163.7;pericyte: 160.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003677, HPA035330" Approved Approved "Nuclear membrane" NA NA 5400000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 21: Non-specific - Metabolism" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 19 "Nuclear membrane" "CAB003677: , HPA035330: " "unprognostic (2.14e-1)" "unprognostic (1.58e-1)" "unprognostic (5.57e-2)" "unprognostic (3.12e-2)" "unprognostic (1.76e-1)" "unprognostic (2.99e-2)" "unprognostic (1.65e-1)" "potential prognostic unfavorable (1.91e-5)" "potential prognostic unfavorable (6.74e-4)" "unprognostic (1.91e-3)" "potential prognostic favorable (6.92e-4)" "unprognostic (1.58e-1)" "unprognostic (2.75e-1)" "potential prognostic unfavorable (1.30e-5)" "unprognostic (8.95e-2)" "unprognostic (3.03e-2)" "potential prognostic unfavorable (6.23e-4)" "potential prognostic unfavorable (7.48e-4)" "unprognostic (1.10e-2)" "unprognostic (2.97e-1)" "unprognostic (6.88e-2)" "unprognostic (9.71e-3)" "unprognostic (1.55e-1)" "unprognostic (9.47e-2)" "unprognostic (1.09e-1)" "unprognostic (4.07e-2)" "unprognostic (1.67e-1)" "unprognostic (1.56e-3)" "unprognostic (1.29e-1)" "unprognostic (1.38e-1)" "unprognostic (1.26e-1)" ANXA6 ANX6 ENSG00000197043 "Annexin A6" P08133 5 151100706-151157815 "Plasma proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 233.1;Hepatic stellate cells: 309.8;Peritubular myoid cells: 216.4;Rod photoreceptor cells: 275.8;Syncytiotrophoblasts: 277.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002462, CAB005077, HPA009650, HPA009977" Enhanced Approved "Basal body,Cytosol" NA NA 1600000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 55: Lymphoma - Immune response" "Cluster 62: Smooth muscle cells - Muscle contraction" 7 Cytosol "Basal body" "CAB005077: , HPA002462: , HPA009650: , HPA009977: " "unprognostic (1.27e-1)" "unprognostic (3.35e-1)" "unprognostic (1.84e-2)" "unprognostic (6.13e-2)" "unprognostic (6.87e-2)" "unprognostic (5.30e-2)" "unprognostic (1.78e-1)" "unprognostic (1.10e-1)" "unprognostic (4.78e-2)" "unprognostic (1.46e-1)" "unprognostic (1.69e-2)" "unprognostic (2.61e-1)" "unprognostic (4.98e-3)" "unprognostic (1.42e-1)" "unprognostic (7.79e-3)" "unprognostic (5.10e-2)" "unprognostic (1.55e-1)" "unprognostic (1.04e-2)" "unprognostic (2.22e-1)" "unprognostic (3.70e-3)" "unprognostic (1.99e-2)" "potential prognostic favorable (8.80e-4)" "unprognostic (8.95e-2)" "unprognostic (3.09e-2)" "unprognostic (8.52e-2)" "unprognostic (2.04e-2)" "unprognostic (2.48e-1)" "unprognostic (6.69e-2)" "unprognostic (3.40e-1)" "unprognostic (1.59e-3)" "unprognostic (2.58e-2)" ANXA7 ANX7 ENSG00000138279 "Annexin A7" P20073 10 73375101-73414076 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 819.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB004312 Approved NA NA 700000 "Cluster 35: Neutrophils - Protein binding" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 14: Neurons - Synaptic function" "Cluster 52: Non-specific - Mitochondria" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 5 "CAB004312: " "unprognostic (1.93e-2)" "unprognostic (2.94e-2)" "unprognostic (5.22e-2)" "unprognostic (2.73e-1)" "unprognostic (1.08e-1)" "unprognostic (1.45e-1)" "unprognostic (2.74e-1)" "unprognostic (6.53e-3)" "unprognostic (2.31e-1)" "unprognostic (3.13e-1)" "potential prognostic favorable (4.47e-8)" "unprognostic (7.19e-2)" "unprognostic (2.09e-3)" "unprognostic (2.45e-1)" "unprognostic (7.47e-2)" "unprognostic (8.50e-2)" "unprognostic (2.12e-1)" "unprognostic (1.92e-1)" "unprognostic (1.76e-1)" "unprognostic (6.56e-2)" "unprognostic (2.62e-2)" "unprognostic (1.97e-1)" "unprognostic (3.80e-1)" "unprognostic (1.69e-1)" "unprognostic (2.41e-1)" "unprognostic (2.36e-1)" "unprognostic (7.08e-2)" "unprognostic (1.82e-1)" "unprognostic (9.93e-2)" "unprognostic (2.45e-2)" "unprognostic (5.53e-2)" ANXA8 ANX8 ENSG00000265190 "Annexin A8" P13928 10 47460162-47484158 "Predicted intracellular proteins" "Blood coagulation, Hemostasis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 174.6;skin 1: 252.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 21.1;Basal keratinocytes: 57.0;Endometrial secretory cells: 23.0;Epicardial cells: 63.7;Esophageal apical cells: 28.4;Esophageal basal cells: 35.3;Esophageal suprabasal cells: 67.6;Mesothelial cells: 51.3;Migrating cytotrophoblasts: 36.4;Ocular epithelial cells: 40.7;Prostatic hillock cells: 35.9;Suprabasal keratinocytes: 91.6;Urothelial cells: 33.0" "Cell type enhanced" "Detected in single" "astrocyte: 1.1" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 121.9;Head and Neck Squamous Cell Carcinoma (TCGA): 193.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.6" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "head and neck cancer: 250.8" "Adipose visceral - Mesothelial cells, Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Urothelial cells, Skin - Keratinocyte (other)" HPA046702 Approved Vesicles NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 29: Forebrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 26: Keratinocytes - Keratinization" 33 Vesicles "HPA046702: " "unprognostic (1.22e-1)" "unprognostic (1.05e-3)" "unprognostic (2.82e-2)" "unprognostic (4.31e-2)" "unprognostic (1.28e-1)" "unprognostic (8.30e-2)" "potential prognostic unfavorable (5.65e-5)" "unprognostic (1.19e-1)" "unprognostic (7.36e-2)" "unprognostic (1.24e-2)" "unprognostic (4.93e-2)" "unprognostic (8.23e-3)" "unprognostic (8.46e-2)" "potential prognostic unfavorable (1.72e-4)" "unprognostic (6.17e-2)" "potential prognostic unfavorable (9.96e-5)" "unprognostic (2.41e-1)" "unprognostic (1.94e-1)" "unprognostic (5.43e-3)" "unprognostic (4.69e-1)" "unprognostic (3.89e-2)" ANXA8L1 "ANXA8L2, bA145E20.2, bA301J7.3" ENSG00000264230 "Annexin A8 like 1" Q5VT79 10 46375627-46391784 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 174.7;skin 1: 307.2" "Cell type enriched" "Detected in some" 5 "Epicardial cells: 34.1" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Bladder Urothelial Carcinoma (TCGA): 76.6;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 93.7;Head and Neck Squamous Cell Carcinoma (TCGA): 157.2;Lung Squamous Cell Carcinoma (TCGA): 65.6" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.2;myeloid DC: 2.1" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "cervical cancer: 189.5;head and neck cancer: 224.9" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 1, Prostate - Urothelial cells, Skin - Keratinocyte (other)" HPA046702 Approved Vesicles NA NA "Cluster 58: Skin - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 3 Vesicles "HPA046702: " "unprognostic (1.16e-1)" "unprognostic (3.49e-3)" "unprognostic (7.75e-2)" "potential prognostic unfavorable (5.58e-4)" "unprognostic (3.68e-3)" "unprognostic (1.66e-1)" "unprognostic (3.01e-2)" "unprognostic (1.53e-1)" "unprognostic (2.84e-2)" "unprognostic (4.02e-2)" "potential prognostic unfavorable (2.15e-5)" "unprognostic (9.50e-3)" "potential prognostic unfavorable (3.03e-5)" "unprognostic (3.23e-2)" "unprognostic (1.48e-1)" "unprognostic (3.41e-2)" "unprognostic (2.98e-1)" ANXA9 ANX31 ENSG00000143412 "Annexin A9" O76027 1 150982249-150995634 "Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 5 "Esophageal apical cells: 392.9" "Cell type enhanced" "Detected in some" "endothelial cell: 3.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 1.6" "Group enriched" "Detected in many" 4 "dendritic cells: 1.6;granulocytes: 1.0;monocytes: 1.2" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Breast - Breast glandular cells, Liver - Hepatocytes, Skin - Keratinocyte (granular), Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA028404, HPA028698" Enhanced Approved "Nuclear speckles,Cytosol" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 76: Non-specific - Metabolism" "Cluster 30: White matter - Myelination" "Cluster 27: Breast cancer - Unknown function" "Cluster 84: Apical squamous epithelium - Cornification" 23 "Nuclear speckles, Cytosol" "HPA028404: , HPA028698: " "unprognostic (2.40e-1)" "unprognostic (1.85e-1)" "unprognostic (1.94e-1)" "unprognostic (1.62e-1)" "unprognostic (3.60e-2)" "unprognostic (7.85e-2)" "unprognostic (9.92e-3)" "unprognostic (8.50e-2)" "unprognostic (1.38e-1)" "validated prognostic favorable (1.11e-4)" "validated prognostic favorable (3.33e-4)" "unprognostic (2.41e-1)" "unprognostic (3.31e-2)" "unprognostic (3.33e-3)" "unprognostic (3.47e-2)" "unprognostic (5.16e-2)" "unprognostic (7.38e-2)" "unprognostic (1.23e-1)" "unprognostic (1.37e-1)" "unprognostic (1.92e-1)" "unprognostic (2.47e-2)" "unprognostic (1.88e-1)" "unprognostic (1.59e-1)" "unprognostic (1.18e-1)" "unprognostic (6.69e-3)" "unprognostic (2.15e-2)" "unprognostic (4.11e-2)" "unprognostic (2.24e-2)" "unprognostic (7.65e-2)" "unprognostic (3.06e-2)" AOAH ENSG00000136250 "Acyloxyacyl hydrolase" P28039 7 36512941-36724549 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 40.9;lymphoid tissue: 61.2" "Cell type enhanced" "Detected in many" "cDC: 579.4;Kupffer cells: 632.4;Macrophages: 488.7;Microglia: 880.0;Monocyte progenitors: 261.5;monocytes: 716.5;Neutrophil progenitors: 321.5;Neutrophils: 1296.5;NK-cells: 1697.6;T-cells: 864.3" "Group enriched" "Detected in all" 18 "central nervous system macrophage: 1165.5;leukocyte: 1282.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 298.8" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 9 "colorectal cancer: 4.5;Leukemia: 5.7;lymphoma: 5.7" "Adrenal gland - Macrophages, Breast - T-cells, Prostate - T-cells, Spleen - Macrophages, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA021666, HPA026716" Approved Approved "Endoplasmic reticulum,Vesicles" "Secreted to blood" Enzyme NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 1 Vesicles "Endoplasmic reticulum" "HPA021666: , HPA026716: " "unprognostic (1.45e-1)" "unprognostic (1.05e-1)" "unprognostic (4.19e-2)" "unprognostic (9.50e-3)" "unprognostic (2.77e-1)" "unprognostic (7.73e-2)" "unprognostic (3.90e-1)" "unprognostic (1.22e-2)" "unprognostic (7.04e-2)" "unprognostic (3.22e-1)" "potential prognostic favorable (4.23e-4)" "unprognostic (9.45e-2)" "unprognostic (1.11e-1)" "unprognostic (1.59e-1)" "unprognostic (1.95e-3)" "unprognostic (5.69e-2)" "unprognostic (1.02e-1)" "unprognostic (3.77e-3)" "unprognostic (1.10e-1)" "unprognostic (1.92e-1)" "unprognostic (4.07e-1)" "unprognostic (1.84e-1)" "unprognostic (1.06e-1)" "unprognostic (1.17e-1)" "unprognostic (4.96e-3)" "potential prognostic favorable (1.88e-7)" "unprognostic (1.27e-1)" "unprognostic (6.69e-2)" "unprognostic (2.34e-3)" "unprognostic (3.73e-1)" "unprognostic (8.12e-2)" AOC1 "ABP, ABP1, DAO" ENSG00000002726 "Amine oxidase copper containing 1" P19801 7 150824627-150861504 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Heparin-binding, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 16 "intestine: 214.1;kidney: 127.7;placenta: 466.7" "Cell type enhanced" "Detected in many" "Colonocytes: 367.0;Enteric transient amplifying cells: 94.8;Enterocytes: 939.7;Extravillous trophoblasts: 129.4;Foveolar cells: 80.3;Goblet cells: 119.5;Renal collecting duct principal cells: 100.3;Tuft cells: 172.9" "Group enriched" "Detected in some" 4 "ependymal cell: 3.5;midbrain-derived inhibitory: 2.6" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 170.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 12 "eosinophil: 31.3" "Lineage enriched" "Detected in many" 22 "granulocytes: 31.3" "Cancer enhanced" "Detected in many" "colorectal cancer: 48.4" "Colon - Colon enterocytes, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA031032, HPA031033" Approved "Secreted in other tissues" Enzyme NA NA 27000000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 46: Brainstem - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 8 "HPA031032: , HPA031033: " "unprognostic (2.72e-2)" "unprognostic (2.38e-2)" "unprognostic (5.78e-2)" "unprognostic (1.84e-2)" "unprognostic (1.86e-1)" "unprognostic (2.82e-2)" "unprognostic (6.01e-2)" "validated prognostic favorable (1.51e-6)" "validated prognostic favorable (5.42e-4)" "unprognostic (1.21e-2)" "unprognostic (6.02e-3)" "unprognostic (1.37e-1)" "unprognostic (2.23e-1)" "unprognostic (3.44e-3)" "unprognostic (1.00e-1)" "unprognostic (2.26e-1)" "unprognostic (2.15e-2)" "unprognostic (1.10e-1)" "unprognostic (4.03e-3)" "unprognostic (6.11e-3)" "unprognostic (3.95e-2)" "unprognostic (1.36e-2)" "unprognostic (8.16e-2)" "unprognostic (2.17e-2)" "unprognostic (1.83e-1)" "potential prognostic unfavorable (9.51e-4)" AOC2 "DAO2, RAO" ENSG00000131480 "Amine oxidase copper containing 2" O75106 17 42844580-42850707 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Catecholamine metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 4 "Early spermatids: 37.1" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 5.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "neutrophil: 1.1" "Lineage enriched" "Detected in single" 7 "granulocytes: 1.1" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Pituitary gland - Corticotropes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA057779 Uncertain NA NA 8800000 "Cluster 35: Neutrophils - Protein binding" "Cluster 67: Testis - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 2 "HPA057779: " "unprognostic (2.20e-1)" "unprognostic (5.36e-2)" "unprognostic (4.99e-2)" "unprognostic (1.95e-2)" "unprognostic (8.25e-2)" "unprognostic (5.57e-3)" "unprognostic (4.27e-2)" "unprognostic (2.69e-1)" "unprognostic (1.15e-1)" AOC3 "HPAO, VAP-1, VAP1" ENSG00000131471 "Amine oxidase copper containing 3" Q16853 17 42851184-42858130 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 397.0;blood vessel: 328.7" "Cell type enhanced" "Detected in some" "Adipocytes: 92.6;Decidual stromal cells: 33.5;Hepatic stellate cells: 77.5;Pericytes: 79.1;Peritubular myoid cells: 72.4;Smooth muscle cells: 117.4;Vascular smooth muscle cells: 150.4" "Cell type enriched" "Detected in some" 64 "vascular associated smooth muscle cell: 85.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Smooth muscle cells, Kidney - Fibroblasts, Lung - Fibroblasts_1, Prostate - Smooth muscle cells, Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA000980, CAB025797" Enhanced Approved "Golgi apparatus,Cytosol" NA NA 120000000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 10 Cytosol "Golgi apparatus" "CAB025797: , HPA000980: " "unprognostic (1.16e-3)" "unprognostic (2.57e-1)" "unprognostic (9.83e-3)" "unprognostic (3.80e-2)" "unprognostic (4.50e-3)" "unprognostic (1.12e-2)" "unprognostic (1.61e-1)" "unprognostic (3.55e-1)" "unprognostic (2.50e-1)" "unprognostic (2.16e-2)" "unprognostic (6.85e-3)" "unprognostic (3.38e-3)" "potential prognostic unfavorable (1.98e-4)" "unprognostic (1.44e-1)" "unprognostic (1.12e-2)" "unprognostic (7.73e-2)" "unprognostic (1.09e-1)" "unprognostic (1.36e-3)" "potential prognostic unfavorable (2.55e-5)" "unprognostic (2.84e-2)" "unprognostic (1.81e-1)" "unprognostic (1.46e-1)" "unprognostic (3.88e-3)" "unprognostic (9.44e-2)" "unprognostic (5.64e-3)" "unprognostic (4.11e-2)" "unprognostic (6.76e-2)" "unprognostic (4.27e-2)" "unprognostic (4.36e-1)" "unprognostic (1.66e-2)" "unprognostic (7.70e-3)" AOPEP "AP-O, APO, C90RF3, C9orf3, FLJ14675" ENSG00000148120 "Aminopeptidase O (putative)" Q8N6M6 9 94726699-95087159 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Disease variant, Dystonia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Myonuclei: 1086.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Breast - Breast myoepithelial cells, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004633, HPA072729" Approved Approved "Cell Junctions" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 58: Skin - Keratinization" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 62: Smooth muscle cells - Muscle contraction" "Cell Junctions" "HPA004633: , HPA072729: " "unprognostic (7.43e-2)" "unprognostic (7.10e-2)" "unprognostic (4.39e-2)" "unprognostic (2.69e-2)" "unprognostic (6.07e-2)" "unprognostic (1.39e-3)" "unprognostic (1.97e-2)" "unprognostic (1.24e-3)" "unprognostic (2.85e-1)" "validated prognostic favorable (2.94e-7)" "validated prognostic favorable (3.28e-5)" "unprognostic (1.08e-1)" "unprognostic (7.76e-2)" "unprognostic (4.06e-2)" "unprognostic (8.44e-2)" "unprognostic (8.74e-2)" "unprognostic (2.16e-2)" "unprognostic (3.48e-2)" "unprognostic (1.97e-1)" "unprognostic (1.41e-1)" "unprognostic (3.26e-2)" "unprognostic (2.11e-1)" "unprognostic (1.75e-1)" "unprognostic (1.35e-1)" "unprognostic (2.98e-2)" "unprognostic (2.52e-1)" "unprognostic (1.84e-1)" "unprognostic (1.07e-2)" "unprognostic (1.17e-1)" AOX1 "AO, AOH1" ENSG00000138356 "Aldehyde oxidase 1" Q06278 2 200586014-200677064 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "adrenal gland: 283.7;liver: 833.2" "Group enriched" "Detected in many" 4 "Adrenal cortex cells: 895.9;Hepatocytes: 1128.3;Mesothelial cells: 433.6" "Cell type enhanced" "Detected in many" "fibroblast: 27.9" "Cancer enriched" "Detected in many" 7 "Liver Hepatocellular Carcinoma (TCGA): 187.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Proximal tubular cells, Liver - Hepatocytes, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA040199, HPA040215" Enhanced Supported "Nuclear bodies,Microtubules,Cytokinetic bridge,Cytosol" Yes NA 5500000 "Cluster 76: Non-specific - Metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 18: Adrenal cortex cells - Steroidogensis" Cytosol "Nuclear bodies, Microtubules, Cytokinetic bridge" "HPA040199: , HPA040215: " "unprognostic (1.53e-1)" "unprognostic (1.73e-1)" "unprognostic (6.26e-3)" "unprognostic (1.47e-1)" "unprognostic (7.67e-2)" "unprognostic (1.69e-1)" "unprognostic (2.92e-3)" "unprognostic (3.64e-2)" "unprognostic (1.89e-2)" "unprognostic (8.40e-2)" "potential prognostic favorable (3.78e-8)" "unprognostic (1.63e-1)" "potential prognostic favorable (5.22e-4)" "unprognostic (1.90e-2)" "unprognostic (1.35e-2)" "unprognostic (2.30e-1)" "unprognostic (5.91e-3)" "unprognostic (1.24e-1)" "unprognostic (5.66e-2)" "unprognostic (6.18e-2)" "unprognostic (2.20e-1)" "unprognostic (2.41e-2)" "unprognostic (3.81e-3)" "unprognostic (3.19e-2)" "unprognostic (2.27e-1)" "unprognostic (2.57e-2)" "unprognostic (8.54e-3)" "unprognostic (6.41e-3)" "unprognostic (3.60e-2)" AP1AR "2C18, C4orf16, gamma-BAR, PRO0971" ENSG00000138660 "Adaptor related protein complex 1 associated regulatory protein" Q63HQ0 4 112231740-112273110 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 121.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035863, HPA058115" Approved Supported "Golgi apparatus" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 77: Intestine - Digestion" "Cluster 31: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 6 "Golgi apparatus" "HPA035863: , HPA058115: " "unprognostic (5.53e-2)" "unprognostic (2.48e-2)" "unprognostic (1.45e-1)" "unprognostic (2.48e-2)" "unprognostic (2.72e-1)" "unprognostic (4.72e-2)" "unprognostic (3.45e-1)" "unprognostic (1.79e-2)" "unprognostic (1.44e-1)" "unprognostic (4.24e-3)" "validated prognostic favorable (2.51e-10)" "validated prognostic favorable (2.31e-4)" "unprognostic (2.22e-2)" "unprognostic (7.85e-2)" "unprognostic (3.05e-2)" "potential prognostic unfavorable (2.52e-5)" "unprognostic (1.38e-2)" "unprognostic (6.78e-2)" "unprognostic (2.27e-1)" "unprognostic (6.75e-2)" "unprognostic (2.90e-3)" "unprognostic (9.97e-3)" "unprognostic (8.21e-3)" "unprognostic (1.78e-2)" "unprognostic (6.97e-3)" "unprognostic (6.37e-2)" "unprognostic (1.43e-1)" "unprognostic (3.41e-2)" "unprognostic (2.99e-1)" "potential prognostic unfavorable (2.70e-4)" "unprognostic (1.14e-1)" AP1B1 "ADTB1, AP105A, BAM22, CLAPB2" ENSG00000100280 "Adaptor related protein complex 1 subunit beta 1" Q10567 22 29327680-29388583 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Deafness, Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 304.7;Microglia: 264.6" "Cell type enriched" "Detected in all" 5 "central nervous system macrophage: 308.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Lung - Macrophages, Prostate - Prostate glandular cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065226, HPA068520" Approved Supported "Golgi apparatus,Vesicles,Cytosol" NA NA 580000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 41 "Golgi apparatus" "Vesicles, Cytosol" "HPA065226: , HPA068520: " "unprognostic (1.40e-2)" "unprognostic (3.18e-2)" "unprognostic (1.47e-1)" "unprognostic (1.08e-1)" "unprognostic (1.23e-1)" "unprognostic (2.90e-2)" "unprognostic (2.93e-1)" "unprognostic (2.11e-1)" "unprognostic (1.59e-1)" "unprognostic (4.97e-2)" "potential prognostic favorable (4.23e-6)" "unprognostic (3.45e-2)" "unprognostic (4.81e-3)" "potential prognostic unfavorable (7.57e-5)" "unprognostic (1.54e-2)" "unprognostic (1.98e-1)" "unprognostic (3.82e-3)" "unprognostic (6.99e-2)" "unprognostic (8.44e-3)" "unprognostic (3.61e-2)" "unprognostic (3.32e-1)" "unprognostic (1.05e-2)" "unprognostic (2.74e-2)" "unprognostic (1.18e-1)" "unprognostic (2.21e-1)" "unprognostic (6.14e-2)" "unprognostic (2.26e-1)" "unprognostic (9.69e-2)" "unprognostic (1.33e-1)" "unprognostic (2.70e-2)" "unprognostic (1.34e-1)" AP1G1 "ADTG, CLAPG1" ENSG00000166747 "Adaptor related protein complex 1 subunit gamma 1" O43747 16 71729000-71809201 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 726.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009049, HPA041224, HPA070312" Approved Enhanced "Golgi apparatus,Vesicles,Cytosol" NA NA 130000 "Cluster 28: Neutrophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 31 "Golgi apparatus, Vesicles" Cytosol "CAB009049: , HPA041224: , HPA070312: " "unprognostic (4.28e-1)" "unprognostic (8.46e-2)" "unprognostic (2.25e-1)" "unprognostic (3.67e-2)" "unprognostic (1.20e-1)" "unprognostic (1.23e-2)" "unprognostic (1.69e-1)" "unprognostic (8.89e-2)" "unprognostic (3.30e-1)" "unprognostic (1.91e-1)" "potential prognostic favorable (1.32e-8)" "unprognostic (1.20e-2)" "unprognostic (3.54e-3)" "unprognostic (3.19e-2)" "unprognostic (1.11e-1)" "unprognostic (2.43e-1)" "unprognostic (2.08e-2)" "unprognostic (1.65e-3)" "unprognostic (3.81e-2)" "unprognostic (5.62e-2)" "unprognostic (5.03e-2)" "unprognostic (3.01e-3)" "potential prognostic unfavorable (4.16e-5)" "unprognostic (5.39e-2)" "unprognostic (5.12e-3)" "unprognostic (1.76e-1)" "unprognostic (5.00e-2)" "unprognostic (2.78e-1)" "unprognostic (1.30e-1)" "unprognostic (1.52e-1)" "unprognostic (3.84e-1)" AP1G2 G2AD ENSG00000213983 "Adaptor related protein complex 1 subunit gamma 2" O75843 14 23559565-23568070 "Predicted intracellular proteins" "Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Tuft cells: 184.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA004106 Approved NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 35: Neurons - Synaptic function & neurogenesis" 27 "HPA004106: " "unprognostic (3.81e-1)" "unprognostic (4.03e-2)" "unprognostic (6.84e-2)" "unprognostic (2.29e-1)" "unprognostic (2.68e-2)" "unprognostic (4.29e-1)" "unprognostic (8.94e-3)" "unprognostic (3.07e-2)" "unprognostic (3.29e-2)" "unprognostic (2.42e-1)" "potential prognostic unfavorable (2.50e-4)" "unprognostic (1.67e-1)" "unprognostic (2.40e-1)" "unprognostic (1.50e-1)" "unprognostic (4.85e-2)" "unprognostic (4.62e-2)" "unprognostic (7.42e-2)" "unprognostic (1.27e-1)" "unprognostic (2.49e-1)" "unprognostic (1.09e-1)" "unprognostic (1.14e-1)" "unprognostic (3.84e-2)" "unprognostic (1.71e-1)" "unprognostic (3.25e-1)" "unprognostic (1.83e-1)" "unprognostic (8.58e-2)" "unprognostic (6.21e-2)" "unprognostic (5.30e-2)" "unprognostic (1.67e-1)" "unprognostic (9.27e-2)" "unprognostic (2.91e-1)" AP1M1 "AP47, CLAPM2, mu1A" ENSG00000072958 "Adaptor related protein complex 1 subunit mu 1" Q9BXS5 19 16197854-16245906 "Plasma proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 160.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045256, HPA077258" Uncertain Approved Vesicles,Cytosol NA NA 29000 "Cluster 25: Non-specific - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 14: Neurons - Synaptic function" "Cluster 23: Non-specific - Transcription" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 99 "Vesicles, Cytosol" "HPA045256: , HPA077258: " "unprognostic (3.02e-1)" "unprognostic (3.22e-1)" "unprognostic (1.51e-1)" "unprognostic (2.90e-1)" "unprognostic (6.12e-2)" "unprognostic (1.37e-1)" "unprognostic (2.33e-1)" "unprognostic (2.36e-2)" "unprognostic (1.94e-1)" "unprognostic (1.70e-2)" "unprognostic (2.69e-1)" "unprognostic (1.99e-2)" "unprognostic (2.83e-1)" "unprognostic (1.44e-2)" "potential prognostic unfavorable (9.66e-6)" "unprognostic (3.86e-1)" "unprognostic (1.43e-1)" "unprognostic (2.93e-2)" "unprognostic (1.00e-1)" "unprognostic (1.33e-1)" "unprognostic (1.77e-1)" "unprognostic (9.79e-2)" "unprognostic (1.95e-2)" "unprognostic (2.15e-1)" "unprognostic (1.30e-1)" "potential prognostic favorable (5.52e-4)" "unprognostic (1.63e-1)" "unprognostic (1.28e-2)" "unprognostic (2.98e-1)" "unprognostic (1.05e-1)" "unprognostic (1.29e-1)" AP1M2 "AP1-mu2, HSMU1B, mu2" ENSG00000129354 "Adaptor related protein complex 1 subunit mu 2" Q9Y6Q5 19 10572671-10587315 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast lactating cells: 125.5;Colonocytes: 140.4;Cytotrophoblasts: 141.6;Enteric transient amplifying cells: 137.9;Enterocytes: 148.3;Esophageal apical cells: 195.5;Migrating cytotrophoblasts: 179.0" "Cell type enhanced" "Detected in single" "miscellaneous: 1.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "basophil: 4.3;neutrophil: 7.7" "Lineage enriched" "Detected in many" 5 "granulocytes: 7.7" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Liver - Cholangiocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA054999, HPA077258" Supported Vesicles,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 60: Stomach - Digestion" "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 23 Vesicles Cytosol "HPA054999: , HPA077258: " "unprognostic (1.02e-1)" "unprognostic (6.96e-2)" "unprognostic (9.25e-3)" "unprognostic (2.58e-1)" "unprognostic (2.42e-2)" "unprognostic (2.64e-2)" "unprognostic (1.23e-1)" "unprognostic (3.66e-2)" "unprognostic (4.72e-2)" "unprognostic (1.99e-1)" "unprognostic (7.02e-2)" "validated prognostic unfavorable (4.41e-4)" "validated prognostic unfavorable (1.18e-4)" "unprognostic (1.17e-1)" "unprognostic (7.42e-2)" "unprognostic (1.02e-1)" "unprognostic (3.39e-1)" "unprognostic (7.19e-2)" "potential prognostic unfavorable (3.26e-4)" "unprognostic (1.99e-1)" "unprognostic (2.07e-2)" "unprognostic (1.48e-1)" "unprognostic (9.80e-2)" "unprognostic (5.06e-2)" "unprognostic (2.82e-1)" "unprognostic (2.37e-2)" "unprognostic (1.87e-1)" "unprognostic (5.16e-2)" "unprognostic (5.86e-2)" AP1S1 "AP19, CLAPS1, EKV3, SIGMA1A, WUGSC:H_DJ0747G18.2" ENSG00000106367 "Adaptor related protein complex 1 subunit sigma 1" P61966 7 101154456-101161596 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Deafness, Ichthyosis, Intellectual disability, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 116.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 196.6;Enterocytes: 208.9;Esophageal basal cells: 147.3;Migrating cytotrophoblasts: 205.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Pituitary gland - Lactotropes, Prostate - Prostate glandular cells, Skin - Keratinocyte (other), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060945 Supported Supported "Golgi apparatus,Vesicles" NA Yes "Cluster 13: Non-specific - Mitochondria" "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 18 "Golgi apparatus, Vesicles" "HPA060945: " "unprognostic (1.92e-2)" "unprognostic (1.53e-3)" "unprognostic (3.09e-1)" "potential prognostic unfavorable (1.58e-6)" "unprognostic (4.05e-1)" "unprognostic (7.64e-2)" "potential prognostic unfavorable (1.44e-4)" "unprognostic (3.74e-1)" "unprognostic (1.14e-2)" "unprognostic (5.77e-3)" "unprognostic (3.59e-3)" "unprognostic (2.14e-1)" "unprognostic (5.07e-3)" "potential prognostic unfavorable (2.69e-4)" "unprognostic (9.89e-3)" "unprognostic (1.59e-2)" "unprognostic (2.05e-2)" "unprognostic (4.17e-2)" "unprognostic (3.64e-1)" "unprognostic (1.43e-1)" "unprognostic (1.10e-2)" "unprognostic (1.43e-1)" "unprognostic (4.47e-1)" "unprognostic (3.74e-2)" "unprognostic (4.01e-2)" "unprognostic (1.15e-1)" "unprognostic (1.30e-1)" "unprognostic (8.61e-3)" "unprognostic (4.92e-1)" "potential prognostic unfavorable (4.89e-4)" "unprognostic (1.31e-3)" AP1S2 "MRX59, MRXS5, PGS, SIGMA1B" ENSG00000182287 "Adaptor related protein complex 1 subunit sigma 2" P56377 X 15825806-15854931 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "epididymis: 621.5" "Cell type enriched" "Detected in many" 4 "Epididymal principal cells: 1800.7" "Cell type enhanced" "Detected in all" "CGE interneuron: 286.9" "Group enriched" "Detected in all" 4 "Glioblastoma Multiforme (TCGA): 91.7;Skin Cutaneous Melanoma (TCGA): 188.9;Uterine Corpus Endometrial Carcinoma (TCGA): 47.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 326.1;intermediate monocyte: 324.4;myeloid DC: 220.8;non-classical monocyte: 175.6;plasmacytoid DC: 81.9" "Group enriched" "Detected in all" 5 "dendritic cells: 220.8;monocytes: 326.1" "Cancer enhanced" "Detected in all" "skin cancer: 184.4" "Breast - Endothelial cells, Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049894, HPA060945" Enhanced Supported "Golgi apparatus,Vesicles" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 22: Epididymis - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 14 "Golgi apparatus, Vesicles" "HPA049894: , HPA060945: " "unprognostic (4.92e-2)" "unprognostic (2.29e-2)" "unprognostic (6.55e-2)" "unprognostic (5.35e-2)" "unprognostic (4.54e-2)" "unprognostic (2.39e-1)" "unprognostic (1.44e-2)" "unprognostic (4.64e-2)" "unprognostic (2.84e-1)" "unprognostic (1.53e-2)" "potential prognostic favorable (6.64e-4)" "unprognostic (2.43e-2)" "unprognostic (7.05e-2)" "potential prognostic unfavorable (1.93e-4)" "unprognostic (8.40e-2)" "unprognostic (1.29e-2)" "unprognostic (1.41e-3)" "unprognostic (1.06e-1)" "unprognostic (9.02e-2)" "potential prognostic favorable (1.59e-4)" "unprognostic (1.65e-1)" "unprognostic (2.42e-2)" "unprognostic (1.65e-1)" "unprognostic (6.04e-2)" "unprognostic (7.13e-2)" "unprognostic (1.97e-2)" "unprognostic (4.49e-2)" "unprognostic (2.58e-2)" "unprognostic (1.86e-1)" "unprognostic (4.29e-1)" "unprognostic (1.67e-1)" AP1S3 sigma1C ENSG00000152056 "Adaptor related protein complex 1 subunit sigma 3" Q96PC3 2 223667680-223838027 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 45.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 77.3;Cone photoreceptor cells: 58.0;Cytotrophoblasts: 85.0;Epididymal principal cells: 105.9;Loop of henle epithelial cells: 150.1;Mast cells: 65.8;Papillary tip epithelial cells: 89.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 4.6;dendritic cells: 3.8;granulocytes: 5.6" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA066782 Approved Supported Vesicles NA NA "Cluster 32: Basophils - Transcription" "Cluster 22: Epididymis - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" 9 Vesicles "HPA066782: " "unprognostic (3.08e-3)" "unprognostic (6.42e-3)" "unprognostic (2.69e-1)" "unprognostic (3.33e-3)" "unprognostic (3.89e-1)" "unprognostic (1.65e-1)" "unprognostic (2.04e-1)" "potential prognostic unfavorable (2.31e-4)" "unprognostic (2.88e-1)" "unprognostic (1.38e-1)" "unprognostic (1.11e-2)" "unprognostic (2.37e-2)" "unprognostic (1.58e-2)" "potential prognostic unfavorable (1.81e-4)" "unprognostic (1.42e-3)" "potential prognostic unfavorable (2.89e-5)" "unprognostic (5.16e-3)" "unprognostic (1.58e-2)" "unprognostic (1.40e-1)" "unprognostic (2.00e-1)" "unprognostic (2.60e-1)" "potential prognostic unfavorable (4.91e-5)" "unprognostic (2.81e-3)" "unprognostic (2.15e-1)" "unprognostic (1.73e-1)" "unprognostic (2.27e-2)" "unprognostic (4.29e-2)" "unprognostic (2.00e-2)" "unprognostic (1.55e-1)" "unprognostic (8.04e-3)" "unprognostic (3.39e-2)" AP2A1 "ADTAA, CLAPA1" ENSG00000196961 "Adaptor related protein complex 2 subunit alpha 1" O95782 19 49767001-49807114 "Predicted intracellular proteins, Transporters" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 222.0;Syncytiotrophoblasts: 355.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 20.6" "Lineage enriched" "Detected in all" 4 "monocytes: 20.6" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB004306 Approved Approved Vesicles NA NA 79000 "Cluster 40: Monocytes - Innate immune response" "Cluster 67: Testis - Mixed function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 4: Non-specific - Transcription" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 51 Vesicles "CAB004306: " "unprognostic (3.63e-1)" "unprognostic (5.78e-3)" "unprognostic (2.79e-1)" "unprognostic (2.24e-1)" "unprognostic (1.37e-1)" "unprognostic (7.18e-2)" "unprognostic (4.03e-1)" "unprognostic (2.87e-1)" "unprognostic (1.04e-1)" "unprognostic (3.15e-2)" "unprognostic (2.40e-2)" "unprognostic (1.01e-1)" "unprognostic (8.65e-2)" "unprognostic (3.57e-3)" "unprognostic (2.46e-2)" "unprognostic (7.74e-3)" "unprognostic (6.81e-2)" "unprognostic (4.00e-2)" "unprognostic (2.03e-1)" "unprognostic (2.19e-3)" "unprognostic (1.10e-1)" "unprognostic (3.10e-1)" "unprognostic (1.47e-1)" "unprognostic (6.22e-2)" "unprognostic (2.07e-1)" "unprognostic (2.47e-2)" "unprognostic (2.01e-1)" "unprognostic (2.55e-1)" "unprognostic (4.57e-1)" "unprognostic (2.45e-2)" "unprognostic (3.16e-1)" AP2A2 "ADTAB, CLAPA2, DKFZP564D1864, HIP9, HYPJ, KIAA0899" ENSG00000183020 "Adaptor related protein complex 2 subunit alpha 2" O94973 11 924881-1012245 "Plasma proteins, Predicted intracellular proteins, Transporters" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 50.3" "Cell type enhanced" "Detected in all" "Distal convoluted tubule cells: 198.4;Loop of henle epithelial cells: 127.4;Proximal tubule cells: 209.0;Renal connecting tubule cells: 198.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017514, HPA043040" Supported Supported Nucleoplasm,Vesicles NA NA 26000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 64: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 28 Vesicles Nucleoplasm "CAB017514: , HPA043040: " "unprognostic (1.05e-1)" "unprognostic (1.85e-3)" "unprognostic (2.55e-2)" "unprognostic (9.67e-2)" "unprognostic (1.08e-1)" "unprognostic (2.73e-1)" "unprognostic (2.66e-2)" "unprognostic (9.44e-2)" "unprognostic (1.78e-1)" "unprognostic (2.51e-1)" "unprognostic (1.74e-2)" "unprognostic (2.15e-2)" "unprognostic (2.78e-2)" "unprognostic (1.33e-3)" "unprognostic (3.50e-2)" "unprognostic (2.00e-1)" "unprognostic (1.37e-2)" "unprognostic (2.73e-1)" "unprognostic (2.04e-2)" "unprognostic (8.56e-3)" "unprognostic (1.69e-1)" "unprognostic (1.39e-1)" "unprognostic (4.07e-2)" "unprognostic (1.72e-2)" "unprognostic (1.88e-1)" "unprognostic (2.97e-1)" "unprognostic (1.10e-1)" "unprognostic (3.36e-2)" "unprognostic (4.67e-2)" "unprognostic (1.76e-1)" "unprognostic (2.61e-1)" AP2B1 "ADTB2, CLAPB1" ENSG00000006125 "Adaptor related protein complex 2 subunit beta 1" P63010 17 35578046-35726413 "Cancer-related genes, Predicted intracellular proteins, Transporters" "Endocytosis, Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 613.2;Late spermatids: 1152.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017631, HPA056733, HPA067983" Approved Supported Vesicles NA NA 360000 "Cluster 33: Non-specific - ATP binding" "Cluster 73: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 111 Vesicles "CAB017631: , HPA056733: , HPA067983: " "unprognostic (4.94e-2)" "unprognostic (7.18e-2)" "unprognostic (1.03e-1)" "unprognostic (1.91e-3)" "unprognostic (1.11e-2)" "unprognostic (4.28e-2)" "unprognostic (1.48e-1)" "unprognostic (1.97e-1)" "unprognostic (2.44e-1)" "unprognostic (4.17e-2)" "potential prognostic favorable (3.98e-6)" "unprognostic (2.23e-2)" "unprognostic (1.23e-1)" "potential prognostic unfavorable (4.43e-4)" "unprognostic (5.23e-3)" "unprognostic (1.05e-2)" "unprognostic (1.14e-1)" "unprognostic (6.71e-2)" "unprognostic (1.57e-1)" "unprognostic (1.22e-2)" "unprognostic (5.49e-3)" "unprognostic (2.11e-2)" "unprognostic (4.13e-1)" "unprognostic (1.73e-1)" "unprognostic (9.54e-3)" "unprognostic (6.94e-2)" "unprognostic (2.06e-1)" "unprognostic (1.20e-1)" "unprognostic (1.06e-1)" "unprognostic (1.37e-1)" "unprognostic (1.72e-1)" AP2M1 "AP50, CLAPM1, mu2" ENSG00000161203 "Adaptor related protein complex 2 subunit mu 1" Q96CW1 3 184174689-184184214 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Endocytosis, Protein transport, Transport" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 497.5;Hofbauer cells: 948.1;Late spermatids: 539.6;Platelets: 520.9;Syncytiotrophoblasts: 600.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036849, HPA069870" Uncertain Supported "Plasma membrane" NA NA 6500 "Cluster 29: Non-specific - Unknown function" "Cluster 36: Brain & Liver - Signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 63: Non-specific - Protein processing" "Cluster 97: Non-specific - Cellular respiration" 132 "Plasma membrane" "HPA036849: , HPA069870: " "unprognostic (1.13e-1)" "unprognostic (3.39e-2)" "unprognostic (4.11e-2)" "unprognostic (1.00e-1)" "unprognostic (1.78e-1)" "unprognostic (3.99e-2)" "unprognostic (3.84e-1)" "potential prognostic favorable (7.49e-4)" "unprognostic (7.77e-3)" "unprognostic (2.51e-3)" "unprognostic (2.58e-2)" "potential prognostic unfavorable (4.34e-4)" "unprognostic (1.15e-1)" "validated prognostic unfavorable (2.84e-5)" "validated prognostic unfavorable (9.34e-5)" "potential prognostic unfavorable (5.10e-4)" "unprognostic (1.57e-3)" "unprognostic (1.45e-2)" "unprognostic (7.43e-3)" "unprognostic (1.58e-1)" "unprognostic (2.19e-1)" "unprognostic (7.93e-2)" "unprognostic (1.59e-1)" "unprognostic (4.12e-3)" "unprognostic (6.00e-2)" "unprognostic (3.64e-1)" "unprognostic (1.45e-1)" "unprognostic (1.21e-1)" "unprognostic (5.75e-2)" "unprognostic (5.78e-2)" "unprognostic (3.22e-2)" AP2S1 "CLAPS2, FBH3, FBHOk, HHC3" ENSG00000042753 "Adaptor related protein complex 2 subunit sigma 1" P53680 19 46838136-46850846 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Endocytosis, Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 1223.8;Esophageal basal cells: 602.3;Esophageal suprabasal cells: 1042.9;Hofbauer cells: 1390.2;Kupffer cells: 587.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 4: Non-specific - Transcription" "Cluster 85: Squamous epithelial cells - Keratinization" 53 "unprognostic (9.25e-2)" "unprognostic (1.19e-1)" "unprognostic (1.81e-1)" "unprognostic (1.07e-2)" "unprognostic (6.06e-2)" "unprognostic (1.78e-1)" "unprognostic (3.58e-3)" "unprognostic (1.75e-2)" "unprognostic (1.66e-2)" "unprognostic (5.96e-3)" "unprognostic (1.03e-2)" "unprognostic (4.33e-2)" "unprognostic (2.33e-2)" "validated prognostic unfavorable (2.53e-4)" "validated prognostic unfavorable (1.02e-5)" "potential prognostic unfavorable (3.34e-4)" "unprognostic (1.89e-2)" "unprognostic (5.62e-2)" "unprognostic (3.28e-1)" "unprognostic (2.98e-1)" "unprognostic (8.86e-2)" "unprognostic (2.40e-1)" "unprognostic (4.08e-2)" "unprognostic (2.88e-1)" "unprognostic (1.23e-1)" "unprognostic (1.61e-1)" "unprognostic (7.94e-3)" "unprognostic (1.15e-1)" "unprognostic (2.19e-1)" "unprognostic (8.56e-2)" "unprognostic (1.01e-1)" AP3B1 "ADTB3A, HPS2" ENSG00000132842 "Adaptor related protein complex 3 subunit beta 1" O00203 5 78000522-78294762 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Albinism, Disease variant, Hermansky-Pudlak syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Somatotrophs: 651.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Colon - Macrophages, Pituitary gland - Somatotropes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038347, HPA038737" Approved Approved "Nucleoplasm,Nuclear membrane,Vesicles,Cytosol" NA NA 3200 "Cluster 2: Dendritic cells - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 33 Vesicles "Nucleoplasm, Nuclear membrane, Cytosol" "HPA038347: , HPA038737: " "unprognostic (1.30e-3)" "unprognostic (4.78e-2)" "unprognostic (1.18e-1)" "unprognostic (1.03e-2)" "unprognostic (1.03e-2)" "unprognostic (9.81e-2)" "unprognostic (3.07e-2)" "unprognostic (5.28e-2)" "unprognostic (8.10e-3)" "unprognostic (2.16e-2)" "potential prognostic favorable (2.35e-4)" "unprognostic (1.22e-1)" "unprognostic (2.82e-2)" "potential prognostic unfavorable (2.79e-7)" "unprognostic (1.44e-2)" "potential prognostic unfavorable (1.52e-5)" "unprognostic (1.72e-2)" "unprognostic (1.04e-1)" "unprognostic (1.84e-1)" "unprognostic (2.25e-2)" "unprognostic (2.10e-2)" "unprognostic (1.56e-1)" "unprognostic (1.91e-2)" "unprognostic (1.60e-1)" "unprognostic (1.56e-1)" "unprognostic (1.73e-1)" "unprognostic (1.34e-1)" "unprognostic (2.16e-2)" "unprognostic (1.54e-1)" "unprognostic (2.01e-1)" "unprognostic (1.98e-1)" AP3B2 NAPTB ENSG00000103723 "Adaptor related protein complex 3 subunit beta 2" Q13367 15 82659281-82710112 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" Epilepsy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 46.0;parathyroid gland: 12.0;pituitary gland: 29.9;retina: 30.5" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 95.7;Brain excitatory neurons: 82.8;Brain inhibitory neurons: 71.8;Cone photoreceptor cells: 115.9;Corticotrophs: 100.7;Gonadotrophs: 156.0;Lactotrophs: 127.8;Neuroendocrine cells: 73.8;Other brain neurons: 70.4;Retinal bipolar cells: 104.3;Retinal horizontal cells: 68.1;Rod photoreceptor cells: 306.2;Somatotrophs: 103.5;Thyrotrophs: 106.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 10.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 23.2" "Colon - Colon enteroendocrine cells, Prostate - Prostate basal glandular cells, Spleen - Neutrophils_2, Stomach - Gastric enteroendocrine cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039467, HPA039818" Enhanced Supported Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 24: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 79: Photoreceptor cells - Phototransduction" 4 "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA039467: , HPA039818: " "unprognostic (8.54e-2)" "unprognostic (1.28e-1)" "unprognostic (9.30e-2)" "unprognostic (2.94e-1)" "unprognostic (9.52e-2)" "unprognostic (1.90e-2)" "unprognostic (3.24e-3)" "unprognostic (2.05e-1)" "unprognostic (4.03e-2)" "unprognostic (1.54e-1)" "unprognostic (1.63e-1)" "unprognostic (4.07e-1)" "unprognostic (1.07e-1)" "unprognostic (5.34e-2)" "unprognostic (2.13e-1)" "unprognostic (1.14e-1)" "unprognostic (1.83e-1)" "unprognostic (3.04e-3)" "unprognostic (6.63e-2)" "unprognostic (2.35e-1)" "unprognostic (4.17e-3)" "unprognostic (6.42e-2)" "unprognostic (4.34e-2)" "unprognostic (3.79e-2)" "unprognostic (7.26e-2)" "unprognostic (1.21e-3)" AP3D1 ADTD ENSG00000065000 "Adaptor related protein complex 3 subunit delta 1" O14617 19 2100988-2164468 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Albinism, Hermansky-Pudlak syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074408 Approved Cytosol No No 19000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 1: Neurons - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 8: Non-specific - Secretory pathway" 19 Cytosol "HPA074408: " "unprognostic (7.39e-2)" "unprognostic (6.02e-3)" "unprognostic (2.48e-2)" "unprognostic (1.03e-1)" "unprognostic (1.62e-2)" "unprognostic (1.59e-1)" "unprognostic (2.90e-1)" "unprognostic (2.49e-1)" "unprognostic (2.96e-1)" "potential prognostic unfavorable (1.78e-4)" "potential prognostic favorable (8.34e-5)" "unprognostic (2.90e-1)" "unprognostic (8.11e-3)" "potential prognostic unfavorable (5.45e-4)" "unprognostic (4.89e-3)" "unprognostic (1.83e-1)" "unprognostic (2.92e-3)" "unprognostic (5.04e-2)" "unprognostic (2.50e-1)" "unprognostic (5.38e-2)" "unprognostic (5.78e-2)" "unprognostic (1.42e-2)" "unprognostic (8.71e-2)" "unprognostic (1.03e-1)" "unprognostic (2.59e-1)" "unprognostic (3.06e-3)" "unprognostic (3.84e-2)" "unprognostic (4.20e-2)" "unprognostic (2.80e-2)" "unprognostic (8.44e-2)" "unprognostic (1.90e-3)" AP3M1 ENSG00000185009 "Adaptor related protein complex 3 subunit mu 1" Q9Y2T2 10 74120255-74150842 "Predicted intracellular proteins" "Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045591, HPA048380" Uncertain NA NA 4600 "Cluster 32: Basophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 65: Non-specific - Cell growth & division" 35 "HPA045591: , HPA048380: " "unprognostic (7.43e-2)" "unprognostic (2.79e-3)" "unprognostic (5.94e-1)" "unprognostic (1.10e-2)" "unprognostic (1.24e-1)" "unprognostic (1.62e-1)" "unprognostic (9.35e-2)" "potential prognostic favorable (3.27e-4)" "unprognostic (3.06e-1)" "unprognostic (3.17e-2)" "potential prognostic favorable (6.73e-5)" "unprognostic (1.85e-1)" "unprognostic (1.81e-1)" "unprognostic (4.26e-3)" "unprognostic (1.98e-2)" "unprognostic (2.97e-1)" "unprognostic (2.78e-2)" "unprognostic (3.88e-2)" "unprognostic (1.95e-1)" "unprognostic (2.85e-2)" "unprognostic (5.16e-3)" "unprognostic (9.58e-2)" "unprognostic (3.98e-2)" "unprognostic (2.58e-1)" "unprognostic (1.31e-1)" "unprognostic (2.46e-1)" "unprognostic (1.18e-1)" "unprognostic (1.83e-1)" "unprognostic (1.62e-1)" "unprognostic (5.67e-2)" "unprognostic (7.26e-2)" AP3M2 "AP47B, CLA20" ENSG00000070718 "Adaptor related protein complex 3 subunit mu 2" P53677 8 42152946-42171673 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 82.0;Late spermatids: 110.1;Melanocytes: 103.5;T-cells: 88.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB014876, HPA045591, HPA048380" Approved NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 40: Non-specific - Unknown function" "Cluster 9: T-cells - Adaptive immunity: Regulation" 4 "CAB014876: , HPA045591: , HPA048380: " "unprognostic (3.94e-2)" "unprognostic (1.16e-2)" "unprognostic (8.41e-3)" "unprognostic (1.02e-1)" "unprognostic (1.98e-2)" "unprognostic (1.11e-1)" "unprognostic (1.08e-1)" "unprognostic (1.67e-2)" "unprognostic (7.10e-2)" "potential prognostic unfavorable (9.77e-4)" "unprognostic (2.30e-3)" "potential prognostic favorable (8.54e-4)" "unprognostic (1.66e-1)" "unprognostic (1.91e-2)" "unprognostic (1.56e-1)" "unprognostic (2.34e-1)" "unprognostic (4.20e-2)" "unprognostic (4.15e-1)" "unprognostic (4.78e-3)" "unprognostic (7.90e-2)" "unprognostic (2.83e-2)" "unprognostic (1.03e-2)" "unprognostic (1.79e-2)" "unprognostic (5.16e-2)" "unprognostic (4.24e-2)" "unprognostic (1.88e-2)" "unprognostic (6.14e-2)" "unprognostic (4.23e-2)" "unprognostic (3.96e-1)" "unprognostic (1.22e-1)" "unprognostic (3.39e-1)" AP3S1 CLAPS3 ENSG00000177879 "Adaptor related protein complex 3 subunit sigma 1" Q92572 5 115841592-115914081 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 514.1;Extravillous trophoblasts: 404.4;Neutrophil progenitors: 338.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049270 Uncertain Approved Vesicles NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 24: Neurons - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 18 Vesicles "HPA049270: " "unprognostic (2.71e-2)" "potential prognostic unfavorable (1.85e-4)" "unprognostic (3.06e-1)" "unprognostic (9.05e-2)" "unprognostic (1.45e-1)" "unprognostic (1.19e-2)" "unprognostic (2.57e-3)" "unprognostic (1.78e-2)" "unprognostic (5.34e-3)" "unprognostic (2.59e-1)" "unprognostic (6.49e-2)" "unprognostic (9.24e-2)" "potential prognostic unfavorable (5.05e-5)" "potential prognostic unfavorable (3.74e-5)" "unprognostic (3.35e-3)" "validated prognostic unfavorable (9.76e-5)" "validated prognostic unfavorable (9.71e-4)" "unprognostic (1.44e-2)" "unprognostic (3.61e-3)" "unprognostic (1.47e-2)" "unprognostic (1.02e-2)" "validated prognostic unfavorable (3.06e-5)" "validated prognostic unfavorable (1.58e-4)" "unprognostic (3.85e-1)" "unprognostic (4.59e-3)" "unprognostic (8.59e-2)" "unprognostic (1.24e-1)" "unprognostic (2.50e-2)" "unprognostic (2.45e-1)" "unprognostic (2.31e-2)" "unprognostic (1.86e-1)" AP3S2 sigma3b ENSG00000157823 "Adaptor related protein complex 3 subunit sigma 2" P59780 15 89830599-89894638 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 53.3;Bergmann glia: 57.4;Brain excitatory neurons: 44.5;Brain inhibitory neurons: 47.3;Choroid plexus epithelial cells: 119.7;Ependymal cells: 54.0;Microglia: 77.8;Oligodendrocyte progenitor cells: 55.9;Oligodendrocytes: 67.6;Other brain neurons: 51.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049270 Uncertain Approved Vesicles NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 76: Non-specific - Metabolism" "Cluster 45: Non-specific - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 22: Non-specific - Basic cellular functions" 4 Vesicles "HPA049270: " "unprognostic (8.70e-2)" "unprognostic (6.65e-3)" "unprognostic (8.24e-2)" "unprognostic (8.64e-2)" "unprognostic (1.12e-1)" "unprognostic (3.02e-1)" "unprognostic (2.99e-1)" "unprognostic (7.89e-2)" "unprognostic (3.91e-2)" "unprognostic (9.27e-2)" "potential prognostic favorable (1.24e-7)" "unprognostic (1.73e-3)" "potential prognostic favorable (6.82e-7)" "unprognostic (1.70e-1)" "unprognostic (2.15e-2)" "unprognostic (6.23e-2)" "unprognostic (2.64e-1)" "unprognostic (2.65e-1)" "unprognostic (1.03e-1)" "unprognostic (1.40e-1)" "unprognostic (7.70e-2)" "unprognostic (1.38e-1)" "unprognostic (3.78e-3)" "unprognostic (1.43e-1)" "unprognostic (1.47e-2)" "unprognostic (2.91e-1)" "unprognostic (7.51e-3)" "unprognostic (8.44e-2)" "unprognostic (1.02e-1)" "unprognostic (2.68e-1)" "unprognostic (1.62e-1)" AP4B1 "BETA-4, SPG47" ENSG00000134262 "Adaptor related protein complex 4 subunit beta 1" Q9Y6B7 1 113894194-113905201 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 42.5;Esophageal apical cells: 39.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028162, HPA028652" Approved Approved Vesicles NA NA "Cluster 41: Basophils - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 84: Apical squamous epithelium - Cornification" 16 Vesicles "HPA028162: , HPA028652: " "unprognostic (3.13e-1)" "unprognostic (2.31e-1)" "unprognostic (8.12e-2)" "unprognostic (1.01e-1)" "unprognostic (1.93e-1)" "unprognostic (6.20e-2)" "unprognostic (1.42e-1)" "unprognostic (9.83e-3)" "unprognostic (3.15e-1)" "unprognostic (2.57e-1)" "unprognostic (1.01e-1)" "unprognostic (1.86e-1)" "unprognostic (9.11e-2)" "potential prognostic unfavorable (1.14e-7)" "unprognostic (1.80e-1)" "unprognostic (7.75e-2)" "unprognostic (2.09e-2)" "unprognostic (2.36e-1)" "unprognostic (7.22e-2)" "unprognostic (4.53e-2)" "unprognostic (2.76e-1)" "unprognostic (1.36e-1)" "unprognostic (3.51e-1)" "unprognostic (1.61e-1)" "unprognostic (6.29e-3)" "unprognostic (2.66e-1)" "unprognostic (5.10e-1)" "unprognostic (1.72e-2)" "unprognostic (2.74e-1)" "unprognostic (2.12e-1)" "unprognostic (6.22e-2)" AP4E1 "AP-4-EPSILON, SPG51" ENSG00000081014 "Adaptor related protein complex 4 subunit epsilon 1" Q9UPM8 15 50908672-51005895 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.7" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041749, HPA041891" Approved NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 58: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" 12 "HPA041749: , HPA041891: " "unprognostic (8.25e-2)" "unprognostic (6.11e-2)" "unprognostic (1.86e-1)" "unprognostic (1.05e-1)" "unprognostic (3.08e-1)" "unprognostic (2.16e-1)" "unprognostic (2.51e-1)" "unprognostic (1.18e-1)" "unprognostic (1.88e-1)" "potential prognostic unfavorable (6.08e-4)" "unprognostic (3.43e-2)" "unprognostic (1.79e-1)" "unprognostic (2.16e-1)" "unprognostic (2.10e-2)" "unprognostic (8.12e-2)" "unprognostic (3.80e-2)" "unprognostic (1.86e-1)" "unprognostic (1.22e-1)" "unprognostic (1.13e-1)" "unprognostic (5.91e-2)" "unprognostic (1.58e-2)" "unprognostic (9.87e-2)" "unprognostic (6.61e-3)" "unprognostic (9.72e-2)" "unprognostic (1.68e-1)" "unprognostic (2.72e-2)" "unprognostic (8.90e-3)" "unprognostic (1.43e-1)" "unprognostic (2.34e-1)" "unprognostic (6.30e-2)" "unprognostic (1.01e-1)" AP4M1 "MU-4, MU-ARP2, SPG50" ENSG00000221838 "Adaptor related protein complex 4 subunit mu 1" O00189 7 100101549-100110345 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 78.9;Late primary spermatocytes: 81.7;Late spermatids: 134.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066774 Approved NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 21: Testis - Mixed function" "Cluster 18: Non-specific - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 65: Non-specific - Cell growth & division" 13 "HPA066774: " "unprognostic (1.53e-1)" "unprognostic (8.05e-2)" "unprognostic (2.83e-1)" "unprognostic (1.14e-1)" "unprognostic (1.10e-1)" "unprognostic (6.34e-2)" "unprognostic (4.82e-3)" "unprognostic (4.05e-2)" "unprognostic (3.31e-2)" "unprognostic (3.91e-2)" "unprognostic (1.81e-1)" "potential prognostic unfavorable (8.30e-4)" "unprognostic (3.34e-3)" "potential prognostic unfavorable (2.65e-4)" "unprognostic (1.29e-3)" "unprognostic (2.37e-1)" "unprognostic (6.55e-3)" "unprognostic (3.46e-1)" "unprognostic (1.36e-1)" "unprognostic (3.46e-1)" "unprognostic (2.08e-1)" "unprognostic (8.94e-2)" "unprognostic (6.26e-3)" "unprognostic (5.39e-1)" "unprognostic (2.01e-1)" "unprognostic (4.86e-2)" "potential prognostic unfavorable (5.88e-4)" "unprognostic (1.51e-1)" "unprognostic (3.38e-1)" "unprognostic (3.34e-1)" "unprognostic (5.98e-2)" AP4S1 "AP47B, CLA20, SPG52" ENSG00000100478 "Adaptor related protein complex 4 subunit sigma 1" Q9Y587 14 31025106-31130996 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 448.9;Epicardial cells: 316.1;Myonuclei: 140.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039963 Approved Supported Vesicles NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 65: Brain - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 5 Vesicles "HPA039963: " "unprognostic (3.25e-1)" "unprognostic (6.34e-2)" "unprognostic (1.54e-1)" "unprognostic (2.71e-1)" "unprognostic (4.02e-2)" "unprognostic (9.42e-3)" "unprognostic (9.40e-2)" "unprognostic (8.34e-3)" "unprognostic (6.60e-3)" "unprognostic (4.96e-3)" "potential prognostic favorable (3.69e-5)" "unprognostic (5.36e-3)" "unprognostic (3.41e-2)" "unprognostic (2.85e-2)" "unprognostic (8.32e-2)" "unprognostic (6.96e-3)" "unprognostic (1.07e-1)" "unprognostic (2.71e-2)" "unprognostic (3.20e-1)" "unprognostic (3.02e-1)" "unprognostic (3.36e-2)" "unprognostic (1.31e-1)" "unprognostic (5.21e-2)" "unprognostic (7.55e-2)" "unprognostic (4.37e-1)" "unprognostic (4.70e-2)" "potential prognostic unfavorable (7.48e-4)" "unprognostic (1.23e-3)" "unprognostic (3.01e-2)" "unprognostic (2.01e-1)" "unprognostic (7.06e-2)" AP5B1 "AP-5, DKFZp761E198, PP1030" ENSG00000254470 "Adaptor related protein complex 5 subunit beta 1" Q2VPB7 11 65773898-65780976 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 41.5" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 57.7;Neutrophil progenitors: 82.5;Neutrophils: 188.6;Syncytiotrophoblasts: 49.1;Urothelial cells: 50.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 14 "neutrophil: 25.0" "Lineage enriched" "Detected in many" 14 "granulocytes: 25.0" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065739, HPA067880" Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 15: Bone marrow - Innate immune response" "Cluster 37: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 11 "Nucleoplasm, Vesicles" "Golgi apparatus" "HPA065739: , HPA067880: " "unprognostic (3.47e-3)" "unprognostic (1.33e-1)" "unprognostic (6.74e-2)" "unprognostic (2.05e-1)" "unprognostic (2.60e-1)" "unprognostic (1.32e-2)" "unprognostic (2.19e-1)" "unprognostic (2.52e-2)" "unprognostic (9.89e-2)" "potential prognostic favorable (9.95e-6)" "unprognostic (2.40e-1)" "unprognostic (1.22e-2)" "unprognostic (5.53e-3)" "unprognostic (1.35e-3)" "unprognostic (5.97e-2)" "unprognostic (1.33e-1)" "unprognostic (8.39e-3)" "unprognostic (7.49e-3)" "unprognostic (2.87e-2)" "unprognostic (1.85e-1)" "unprognostic (3.77e-2)" "unprognostic (1.64e-1)" "unprognostic (4.33e-2)" "unprognostic (1.38e-1)" "unprognostic (5.06e-1)" "unprognostic (8.26e-2)" "unprognostic (2.62e-2)" "unprognostic (3.68e-2)" "unprognostic (2.13e-1)" AP5M1 "C14orf108, FLJ10813, mu5, MuD, MUDENG" ENSG00000053770 "Adaptor related protein complex 5 subunit mu 1" Q9H0R1 14 57268924-57298742 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 195.7;Late spermatids: 142.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055768, HPA057098" Approved NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 76: Non-specific - Metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 97: Non-specific - Cellular respiration" 1 "HPA055768: , HPA057098: " "unprognostic (7.64e-2)" "unprognostic (2.97e-3)" "unprognostic (1.35e-2)" "unprognostic (2.49e-2)" "potential prognostic favorable (3.94e-4)" "unprognostic (6.57e-2)" "unprognostic (1.55e-1)" "unprognostic (4.06e-2)" "unprognostic (3.90e-2)" "potential prognostic favorable (2.36e-9)" "unprognostic (3.53e-3)" "unprognostic (9.78e-3)" "unprognostic (1.46e-1)" "unprognostic (1.99e-2)" "unprognostic (2.87e-2)" "unprognostic (9.95e-2)" "unprognostic (4.91e-2)" "unprognostic (2.74e-2)" "unprognostic (9.53e-3)" "unprognostic (3.37e-1)" "unprognostic (2.42e-1)" "unprognostic (1.09e-1)" "unprognostic (2.53e-3)" "potential prognostic unfavorable (8.29e-4)" "unprognostic (5.58e-2)" "unprognostic (8.76e-2)" "unprognostic (8.80e-2)" "unprognostic (6.62e-2)" "unprognostic (9.68e-2)" AP5S1 "C20orf29, FLJ11168" ENSG00000125843 "Adaptor related protein complex 5 subunit sigma 1" Q9NUS5 20 3820524-3828838 "Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 28.7;Platelets: 53.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034200, HPA043533, HPA048244" Uncertain Approved Nucleoplasm,Cytosol No No "Cluster 33: Non-specific - ATP binding" "Cluster 52: Non-specific - Cellular respiration" "Cluster 33: Neurons - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 47: Platelets - Hemostasis" 10 "Nucleoplasm, Cytosol" "CAB034200: , HPA043533: , HPA048244: " "unprognostic (1.22e-2)" "potential prognostic unfavorable (7.04e-4)" "unprognostic (4.64e-2)" "unprognostic (2.99e-2)" "unprognostic (1.50e-1)" "unprognostic (2.54e-2)" "unprognostic (3.27e-2)" "unprognostic (1.73e-1)" "unprognostic (4.06e-2)" "unprognostic (1.84e-3)" "unprognostic (7.96e-2)" "potential prognostic favorable (6.87e-4)" "unprognostic (1.13e-2)" "unprognostic (1.95e-1)" "unprognostic (5.94e-2)" "potential prognostic unfavorable (1.76e-5)" "unprognostic (3.21e-1)" "unprognostic (9.60e-3)" "unprognostic (2.38e-1)" "unprognostic (1.52e-2)" "unprognostic (1.11e-1)" "unprognostic (2.97e-2)" "unprognostic (1.08e-1)" "unprognostic (4.58e-2)" "unprognostic (3.55e-1)" "unprognostic (4.31e-1)" "unprognostic (2.57e-1)" "unprognostic (3.52e-2)" "unprognostic (8.72e-2)" AP5Z1 "KIAA0415, SPG48, zeta" ENSG00000242802 "Adaptor related protein complex 5 subunit zeta 1" O43299 7 4775615-4794397 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair, Protein transport, Transport" "Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hofbauer cells: 89.5;Neutrophils: 124.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035693 Supported Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 2: Non-specific - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 65: Non-specific - Cell growth & division" 1 "Nuclear speckles" Nucleoplasm "HPA035693: " "unprognostic (7.85e-2)" "unprognostic (1.68e-1)" "unprognostic (2.21e-2)" "unprognostic (1.26e-2)" "unprognostic (2.59e-1)" "unprognostic (4.59e-2)" "unprognostic (4.60e-2)" "unprognostic (1.82e-1)" "unprognostic (1.82e-1)" "potential prognostic unfavorable (3.61e-7)" "unprognostic (1.74e-1)" "unprognostic (9.75e-2)" "potential prognostic unfavorable (2.32e-4)" "unprognostic (2.91e-1)" "unprognostic (4.70e-2)" "unprognostic (3.13e-2)" "unprognostic (3.48e-2)" "unprognostic (6.43e-2)" "unprognostic (1.49e-1)" "potential prognostic favorable (3.19e-4)" "unprognostic (4.14e-2)" "unprognostic (3.47e-2)" "unprognostic (2.21e-1)" "unprognostic (1.87e-3)" "unprognostic (3.78e-1)" "unprognostic (2.58e-1)" "unprognostic (8.46e-2)" "unprognostic (5.03e-2)" "unprognostic (1.09e-1)" APAF1 "APAF-1, CED4" ENSG00000120868 "Apoptotic peptidase activating factor 1" O14727 12 98645290-98735433 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" Apoptosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 30.3" "Cell type enhanced" "Detected in many" "Microglia: 136.5;Monocyte progenitors: 161.0;monocytes: 112.5;Neutrophil progenitors: 499.2;Neutrophils: 353.5" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 180.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 71.4" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031373, CAB069399" Enhanced Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 34: Non-specific - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 16 "Nucleoplasm, Cytosol" "Golgi apparatus" "CAB069399: , HPA031373: " "unprognostic (1.39e-1)" "unprognostic (1.12e-1)" "unprognostic (5.35e-2)" "unprognostic (6.89e-3)" "unprognostic (2.20e-2)" "unprognostic (1.58e-1)" "unprognostic (3.27e-1)" "unprognostic (7.30e-3)" "unprognostic (1.82e-2)" "unprognostic (8.64e-2)" "unprognostic (5.79e-2)" "unprognostic (8.83e-2)" "unprognostic (2.43e-1)" "unprognostic (2.30e-3)" "potential prognostic unfavorable (8.94e-4)" "unprognostic (1.81e-1)" "unprognostic (2.62e-2)" "unprognostic (2.87e-1)" "unprognostic (1.48e-1)" "unprognostic (6.14e-3)" "unprognostic (5.30e-2)" "unprognostic (9.61e-2)" "unprognostic (9.04e-2)" "unprognostic (1.58e-1)" "potential prognostic favorable (8.58e-4)" "unprognostic (9.72e-2)" "unprognostic (7.46e-2)" "unprognostic (6.65e-2)" "unprognostic (2.95e-1)" "unprognostic (3.58e-2)" "unprognostic (4.75e-1)" APBA1 "D9S411E, MINT1, X11" ENSG00000107282 "Amyloid beta precursor protein binding family A member 1" Q02410 9 69427532-69672371 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.1" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 280.8;Brain inhibitory neurons: 234.7;Lactotrophs: 161.4;Microglia: 244.4;Oligodendrocyte progenitor cells: 203.2;Other brain neurons: 234.0;Podocytes: 203.9;Retinal amacrine cells: 182.8;Retinal ganglion cells: 216.3;Retinal horizontal cells: 280.5;Somatotrophs: 175.7;Thyrotrophs: 178.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal medulla cells, Liver - Hepatocytes, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061287 Supported "Golgi apparatus" NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 24: Neurons - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 109: Neurons - Neuronal signaling" 22 "Golgi apparatus" "HPA061287: " "unprognostic (1.11e-1)" "unprognostic (1.36e-1)" "unprognostic (2.55e-1)" "potential prognostic favorable (6.56e-4)" "potential prognostic favorable (9.18e-4)" "unprognostic (1.42e-1)" "unprognostic (1.61e-3)" "unprognostic (2.04e-1)" "unprognostic (1.35e-1)" "unprognostic (1.34e-1)" "unprognostic (1.20e-1)" "unprognostic (1.14e-2)" "unprognostic (9.53e-2)" APBA2 "D15S1518E, HsT16821, LIN-10, MGC:14091, MINT2, X11L" ENSG00000034053 "Amyloid beta precursor protein binding family A member 2" Q99767 15 28884483-29118315 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 76.5" "Cell type enhanced" "Detected in some" "Astrocytes: 145.8;Bergmann glia: 163.9;Brain excitatory neurons: 183.0;Brain inhibitory neurons: 104.9;Ependymal cells: 36.2;Microglia: 90.8;NK-cells: 65.1;Oligodendrocyte progenitor cells: 165.6;Oligodendrocytes: 107.1;Other brain neurons: 68.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 10.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 4.5;naive CD8 T-cell: 5.0" "Lineage enriched" "Detected in many" 5 "T-cells: 5.0" "Cancer enhanced" "Detected in many" "Neuroblastoma: 11.3" "Adipose visceral - T-cells, Pituitary gland - Corticotropes, Stomach - T-cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037065, HPA058796, HPA070376" Uncertain Enhanced "Golgi apparatus" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 27: Cerebellum - Synaptic function" "Cluster 15: Non-specific - Transcription" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 102: Non-specific - Mixed function" 13 "Golgi apparatus" "CAB037065: , HPA058796: , HPA070376: " "unprognostic (2.93e-1)" "unprognostic (3.43e-2)" "unprognostic (1.37e-1)" "unprognostic (2.67e-1)" "potential prognostic favorable (3.86e-4)" "unprognostic (6.55e-3)" "potential prognostic favorable (1.57e-4)" "unprognostic (2.11e-1)" "unprognostic (1.73e-1)" "unprognostic (8.14e-2)" "unprognostic (6.71e-2)" "unprognostic (2.82e-1)" "unprognostic (3.18e-1)" "potential prognostic favorable (9.13e-4)" "unprognostic (3.60e-1)" "unprognostic (2.17e-1)" "unprognostic (9.57e-2)" APBA3 "mint3, X11L2" ENSG00000011132 "Amyloid beta precursor protein binding family A member 3" O96018 19 3750772-3761692 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045577 Approved Approved Vesicles NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 24: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 23: Non-specific - Transcription" "Cluster 9: T-cells - Adaptive immunity: Regulation" 33 Vesicles "HPA045577: " "unprognostic (2.93e-1)" "unprognostic (3.42e-1)" "unprognostic (2.78e-2)" "unprognostic (3.24e-3)" "unprognostic (4.71e-2)" "unprognostic (4.77e-3)" "unprognostic (3.57e-2)" "unprognostic (6.38e-2)" "unprognostic (1.57e-3)" "unprognostic (1.88e-1)" "potential prognostic favorable (4.94e-4)" "unprognostic (9.33e-2)" "unprognostic (1.29e-1)" "unprognostic (7.49e-2)" "unprognostic (2.11e-1)" "unprognostic (3.13e-1)" "unprognostic (1.35e-1)" "unprognostic (8.62e-2)" "unprognostic (1.39e-1)" "unprognostic (7.27e-2)" "unprognostic (1.43e-1)" "potential prognostic favorable (2.70e-4)" "unprognostic (8.28e-2)" "unprognostic (2.62e-3)" "unprognostic (4.20e-1)" "unprognostic (3.24e-2)" "unprognostic (1.57e-2)" "unprognostic (1.99e-1)" "unprognostic (2.71e-2)" "unprognostic (4.25e-2)" "unprognostic (1.27e-2)" APBB1 "Fe65, RIR" ENSG00000166313 "Amyloid beta precursor protein binding family B member 1" O00213 11 6395125-6419414 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, DNA damage, Transcription, Transcription regulation" "Activator, Chromatin regulator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 192.4" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 75.7;Oligodendrocyte progenitor cells: 73.7;Oligodendrocytes: 151.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 85.7" "Lineage enriched" "Detected in all" 5 "T-cells: 85.7" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Prostate - Smooth muscle cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038521, HPA038522" Approved Supported "Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 27: Cerebellum - Synaptic function" "Cluster 30: White matter - Myelination" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 80: Oligodendrocytes - Myelination" 32 "Plasma membrane" "Endoplasmic reticulum" "HPA038521: , HPA038522: " "unprognostic (1.55e-1)" "unprognostic (1.95e-1)" "unprognostic (3.80e-2)" "unprognostic (1.15e-1)" "unprognostic (4.00e-3)" "unprognostic (1.65e-1)" "unprognostic (2.01e-1)" "unprognostic (4.07e-2)" "unprognostic (1.33e-1)" "unprognostic (4.69e-2)" "validated prognostic favorable (1.30e-8)" "validated prognostic favorable (5.58e-4)" "unprognostic (1.33e-3)" "unprognostic (2.23e-2)" "unprognostic (5.96e-2)" "unprognostic (3.78e-2)" "unprognostic (1.20e-1)" "unprognostic (6.69e-3)" "unprognostic (8.66e-3)" "unprognostic (2.57e-1)" "unprognostic (5.40e-2)" "potential prognostic favorable (5.98e-5)" "unprognostic (1.92e-1)" "unprognostic (3.38e-1)" "unprognostic (2.75e-1)" "unprognostic (3.64e-3)" "unprognostic (1.72e-2)" "unprognostic (1.67e-2)" "unprognostic (4.05e-2)" "unprognostic (2.62e-1)" "unprognostic (3.21e-1)" APBB1IP "INAG1, RIAM" ENSG00000077420 "Amyloid beta precursor protein binding family B member 1 interacting protein" Q7Z5R6 10 26438341-26567803 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 135.3" "Cell type enhanced" "Detected in many" "Adipocytes: 600.2;Kupffer cells: 435.6;Macrophages: 333.6;Microglia: 2215.0;Monocyte progenitors: 346.9;monocytes: 439.8;Neutrophil progenitors: 864.7;Neutrophils: 2909.8;NK-cells: 353.3;pDCs: 368.0;T-cells: 420.4" "Cell type enriched" "Detected in many" 4 "central nervous system macrophage: 2560.2" "Cancer enhanced" "Detected in all" "Kidney Renal Papillary Cell Carcinoma (TCGA): 42.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 183.4" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Kidney cancer: 43.1;Leukemia: 69.3;lymphoma: 96.1;Myeloma: 25.7" "Adrenal gland - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Minor Salivary Gland - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Spleen - Neutrophils_2, Testis - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA017009, HPA063903" Enhanced Enhanced "Plasma membrane,Cytosol" No NA "Cluster 35: Neutrophils - Protein binding" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 4 "Plasma membrane, Cytosol" "HPA017009: , HPA063903: " "unprognostic (3.10e-1)" "unprognostic (2.32e-2)" "unprognostic (1.06e-1)" "unprognostic (6.05e-2)" "unprognostic (5.30e-2)" "unprognostic (2.66e-1)" "unprognostic (2.73e-1)" "unprognostic (2.02e-1)" "unprognostic (2.92e-2)" "unprognostic (1.47e-1)" "potential prognostic favorable (1.72e-4)" "unprognostic (2.75e-1)" "potential prognostic favorable (9.92e-6)" "unprognostic (1.16e-2)" "unprognostic (1.46e-3)" "unprognostic (5.95e-2)" "unprognostic (3.45e-2)" "unprognostic (6.95e-2)" "unprognostic (3.60e-1)" "unprognostic (2.55e-1)" "unprognostic (5.32e-1)" "unprognostic (3.27e-2)" "unprognostic (6.56e-2)" "unprognostic (1.17e-1)" "unprognostic (2.96e-2)" "unprognostic (2.47e-1)" "unprognostic (7.70e-3)" "unprognostic (7.37e-3)" "unprognostic (7.36e-3)" "unprognostic (1.97e-1)" "unprognostic (2.40e-1)" APBB2 "FE65L, FE65L1, MGC35575" ENSG00000163697 "Amyloid beta precursor protein binding family B member 2" Q92870 4 40810027-41216714 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 752.3;Alveolar cells type 1: 926.5;Distal convoluted tubule cells: 1637.7;Oligodendrocyte progenitor cells: 971.6;Oligodendrocytes: 1046.9;Podocytes: 1784.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 16 "naive B-cell: 5.5" "Lineage enriched" "Detected in single" 24 "B-cells: 5.5" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023542 Approved Approved Mitochondria No No "Cluster 34: B-cells - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 57: Podocytes - Glomerular filtration" 10 Mitochondria "HPA023542: " "unprognostic (1.42e-1)" "unprognostic (2.24e-2)" "unprognostic (2.37e-1)" "potential prognostic unfavorable (1.92e-6)" "unprognostic (1.81e-1)" "unprognostic (1.01e-1)" "unprognostic (6.78e-2)" "unprognostic (1.43e-2)" "unprognostic (1.26e-1)" "unprognostic (2.37e-2)" "potential prognostic favorable (1.12e-4)" "unprognostic (2.32e-3)" "unprognostic (2.29e-1)" "unprognostic (1.99e-1)" "potential prognostic favorable (1.39e-4)" "unprognostic (9.99e-2)" "unprognostic (3.15e-2)" "unprognostic (1.17e-2)" "unprognostic (1.14e-1)" "validated prognostic unfavorable (4.46e-4)" "validated prognostic unfavorable (5.87e-5)" "unprognostic (7.16e-2)" "unprognostic (2.23e-3)" "unprognostic (1.31e-1)" "unprognostic (9.02e-3)" "unprognostic (1.01e-1)" "unprognostic (2.57e-1)" "unprognostic (2.73e-2)" "unprognostic (1.88e-1)" "unprognostic (1.31e-3)" "unprognostic (2.49e-2)" APBB3 FE65L2 ENSG00000113108 "Amyloid beta precursor protein binding family B member 3" O95704 5 140558268-140564781 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.6" "Cell type enhanced" "Detected in many" "Early spermatids: 68.1;Late spermatids: 61.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 5.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005571, HPA076196" Approved Supported "Nuclear bodies,Actin filaments,Cytosol" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 27: Cerebellum - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 17 "Nuclear bodies, Actin filaments" Cytosol "HPA005571: , HPA076196: " "unprognostic (2.46e-2)" "unprognostic (2.67e-2)" "unprognostic (1.07e-1)" "unprognostic (5.44e-2)" "unprognostic (4.82e-2)" "potential prognostic unfavorable (8.06e-7)" "unprognostic (2.23e-1)" "unprognostic (8.71e-2)" "unprognostic (1.84e-1)" "unprognostic (1.32e-3)" "unprognostic (9.39e-2)" "potential prognostic favorable (6.17e-4)" "unprognostic (1.43e-1)" "potential prognostic favorable (6.70e-5)" "unprognostic (2.00e-1)" "unprognostic (5.66e-2)" "unprognostic (2.69e-2)" "unprognostic (4.04e-2)" "potential prognostic favorable (5.10e-4)" "unprognostic (1.03e-3)" "unprognostic (4.04e-3)" "unprognostic (1.18e-1)" "unprognostic (3.67e-1)" "unprognostic (9.83e-2)" "unprognostic (2.34e-1)" "unprognostic (9.60e-3)" APC "DP2, DP2.5, DP3, PPP1R46" ENSG00000134982 "APC regulator of WNT signaling pathway" P25054 5 112707498-112846239 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Wnt signaling pathway" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 38.7" "Cell type enhanced" "Detected in all" "Astrocytes: 738.9;Bergmann glia: 719.6;Ependymal cells: 304.0;Neutrophils: 301.6;Retinal bipolar cells: 296.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pituitary gland - Undifferentiated cells (Pituitary gland), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013349, HPA013362" Supported Supported "Golgi apparatus,Plasma membrane" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 73: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 28: Astrocytes - Homeostasis & neuron support" 94 "Plasma membrane" "Golgi apparatus" "HPA013349: , HPA013362: " "unprognostic (9.53e-2)" "unprognostic (7.72e-2)" "unprognostic (2.61e-1)" "unprognostic (4.76e-2)" "unprognostic (1.47e-1)" "unprognostic (1.77e-1)" "unprognostic (1.33e-1)" "unprognostic (1.87e-1)" "unprognostic (1.13e-2)" "unprognostic (1.55e-2)" "potential prognostic favorable (2.40e-6)" "unprognostic (3.11e-3)" "unprognostic (1.78e-1)" "unprognostic (2.57e-1)" "unprognostic (4.04e-2)" "unprognostic (3.48e-2)" "unprognostic (2.78e-1)" "unprognostic (1.33e-1)" "unprognostic (1.23e-1)" "unprognostic (8.62e-3)" "potential prognostic unfavorable (2.79e-4)" "unprognostic (2.17e-1)" "unprognostic (1.87e-1)" "unprognostic (1.12e-1)" "unprognostic (7.56e-2)" "unprognostic (3.37e-3)" "unprognostic (4.45e-1)" "unprognostic (1.04e-1)" "unprognostic (3.20e-1)" "unprognostic (7.53e-3)" "unprognostic (2.04e-1)" APC2 APCL ENSG00000115266 "APC regulator of WNT signaling pathway 2" O95996 19 1446302-1473244 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Wnt signaling pathway" "Disease variant, Intellectual disability, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "brain: 48.0" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 85.1;Astrocytes: 176.9;Bergmann glia: 105.1;Brain excitatory neurons: 44.0;Brain inhibitory neurons: 47.8;Ependymal cells: 47.5;Müller glia: 57.7;Oligodendrocyte progenitor cells: 58.4;Oligodendrocytes: 40.9;Other brain neurons: 40.1;Retinal amacrine cells: 94.8;Retinal bipolar cells: 52.6;Retinal horizontal cells: 46.1" "Cell type enhanced" "Detected in all" "astrocyte: 210.8" "Cancer enriched" "Detected in some" 28 "Glioblastoma Multiforme (TCGA): 37.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "Neuroblastoma: 34.0;Rhabdoid: 10.6" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078002 Supported "Cytokinetic bridge,Midbody,Primary cilium,Cytosol" Yes No "Cluster 10: Brain - Synaptic signal transduction" "Cluster 19: Astrocytes - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 28: Astrocytes - Homeostasis & neuron support" 6 "Cytokinetic bridge" "Midbody, Primary cilium, Cytosol" "HPA078002: " "unprognostic (4.72e-1)" "unprognostic (1.14e-1)" "unprognostic (1.22e-2)" APCDD1 B7323 ENSG00000154856 "APC down-regulated 1" Q8J025 18 10454635-10489949 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Wnt signaling pathway" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 122.7" "Cell type enhanced" "Detected in many" "Adipocytes: 178.3;Astrocytes: 176.9;Bergmann glia: 133.5;Decidual stromal cells: 253.3;Endometrial stromal cells: 475.0;Fibroblasts: 137.1;Melanocytes: 101.4;Oligodendrocyte progenitor cells: 193.1;Oligodendrocytes: 102.7;Schwann cells: 99.4" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 317.5;endothelial cell: 277.3;fibroblast: 340.2;oligodendrocyte precursor cell: 217.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 113.5" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Kidney - Fibroblasts, Minor Salivary Gland - Minor salivary gland basal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 37: Skin - Keratinization" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 108: Fibroblasts - ECM organization" 2 "potential prognostic favorable (4.55e-5)" "unprognostic (1.45e-1)" "unprognostic (4.06e-1)" "unprognostic (1.17e-2)" "unprognostic (6.95e-2)" "potential prognostic favorable (9.86e-4)" "unprognostic (1.31e-3)" "unprognostic (5.63e-2)" "unprognostic (1.98e-2)" "unprognostic (9.19e-2)" "unprognostic (1.29e-2)" "unprognostic (3.25e-3)" "unprognostic (7.60e-3)" "unprognostic (8.50e-3)" "unprognostic (9.30e-2)" "unprognostic (1.20e-1)" "unprognostic (1.20e-2)" "unprognostic (1.58e-1)" "unprognostic (1.41e-1)" "unprognostic (1.82e-1)" "unprognostic (2.78e-2)" "unprognostic (1.02e-1)" "unprognostic (7.91e-2)" "unprognostic (7.68e-2)" "unprognostic (1.88e-1)" "unprognostic (1.93e-1)" "unprognostic (1.69e-2)" "unprognostic (1.35e-1)" "unprognostic (1.62e-1)" "unprognostic (1.56e-2)" "unprognostic (5.95e-2)" APCDD1L FLJ90166 ENSG00000198768 "APC down-regulated 1 like" Q8NCL9 20 58459101-58515399 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "blood vessel: 5.3;salivary gland: 18.1" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 21.3;Breast secretory cells: 34.2;Cardiomyocytes: 15.0;Corticotrophs: 44.7;Fibro-adipogenic progenitors: 20.6;Lacrimal acinar cells: 100.5;Pancreatic islet cells: 14.6;Renal collecting duct principal cells: 15.1;Renal connecting tubule cells: 72.5" "Cell type enhanced" "Detected in many" "Bergmann glia: 6.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "thyroid cancer: 44.8" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Smooth muscle cells, Stomach - Fibroblasts" "Not detected" "Not detected" HPA067015 Uncertain Uncertain Mitochondria No No "Cluster 82: Salivary gland - Secretion" "Cluster 25: Non-specific - Transcription" "Cluster 72: Neuronal - Signal transduction" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 3 Mitochondria "HPA067015: " "unprognostic (8.93e-2)" "unprognostic (1.66e-1)" "unprognostic (2.89e-1)" "unprognostic (1.30e-2)" "potential prognostic unfavorable (9.71e-5)" "unprognostic (1.88e-2)" "potential prognostic unfavorable (5.30e-6)" "unprognostic (7.15e-3)" "potential prognostic unfavorable (6.60e-4)" "unprognostic (2.97e-2)" "validated prognostic unfavorable (6.10e-4)" "validated prognostic unfavorable (8.07e-4)" "unprognostic (2.88e-2)" APCS "MGC88159, PTX2, SAP" ENSG00000132703 "Amyloid P component, serum" P02743 1 159587826-159588865 "Disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 76 "liver: 3389.4" "Cell type enriched" "Detected in some" 12 "Hepatocytes: 4780.8" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 21 "Liver Hepatocellular Carcinoma (TCGA): 1149.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 10 "liver cancer: 14.2" "Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB007817, HPA053294" Supported "Secreted to blood" "No annotated function" NA NA 27700000000 7600000000 "Cluster 53: Liver - Plasma proteins" "Cluster 7: Liver cancer - Metabolism" "Cluster 93: Hepatocytes - Bile production & excretion" 9 "CAB007817: , HPA053294: " "unprognostic (8.21e-2)" "unprognostic (9.15e-2)" "unprognostic (2.17e-2)" "unprognostic (1.45e-2)" "potential prognostic favorable (1.23e-6)" "unprognostic (2.42e-2)" "potential prognostic unfavorable (1.18e-5)" APEH "D3F15S2, D3S48E, DNF15S2" ENSG00000164062 "Acylaminoacyl-peptide hydrolase" P13798 3 49674014-49683971 "Enzymes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 99.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029700, HPA029701, HPA029702, HPA029703" Enhanced Enhanced Cytosol No No 7900000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 76: Non-specific - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 97: Non-specific - Cellular respiration" 6 Cytosol "HPA029700: , HPA029701: , HPA029702: , HPA029703: " "unprognostic (5.23e-3)" "unprognostic (2.04e-1)" "unprognostic (9.18e-2)" "unprognostic (5.55e-2)" "unprognostic (4.67e-2)" "unprognostic (7.22e-3)" "unprognostic (3.03e-1)" "unprognostic (8.32e-2)" "unprognostic (9.71e-2)" "potential prognostic unfavorable (6.21e-5)" "potential prognostic favorable (1.44e-6)" "unprognostic (1.44e-1)" "potential prognostic favorable (1.56e-4)" "unprognostic (1.67e-1)" "unprognostic (7.13e-2)" "unprognostic (4.32e-1)" "unprognostic (1.10e-2)" "unprognostic (5.32e-2)" "unprognostic (2.89e-2)" "unprognostic (1.41e-1)" "unprognostic (1.60e-2)" "unprognostic (6.60e-2)" "unprognostic (4.37e-2)" "unprognostic (1.03e-1)" "unprognostic (3.48e-2)" "unprognostic (3.25e-1)" "unprognostic (5.04e-2)" "unprognostic (2.27e-2)" "unprognostic (1.91e-1)" "unprognostic (6.50e-2)" "unprognostic (2.69e-2)" APELA "ELA, Ende, tdl" ENSG00000248329 "Apelin receptor early endogenous ligand" P0DMC3 4 164877178-164898965 "Predicted secreted proteins" "Angiogenesis, Differentiation, Gastrulation" "Developmental protein, Hormone" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 1.4;kidney: 2.0;prostate: 4.0" "Cell type enhanced" "Detected in some" "Breast hormone-responsive cells: 12.8;Cytotrophoblasts: 39.0;Migrating cytotrophoblasts: 25.5;Prostatic glandular cells: 9.4;Respiratory ionocytes: 10.2;Syncytiotrophoblasts: 40.6" "Group enriched" "Detected in some" 4 "deep-layer corticothalamic and 6b: 3.5;deep-layer near-projecting: 3.6" "Cancer enhanced" "Detected in some" "Prostate Adenocarcinoma (TCGA): 3.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 7.7;testis cancer: 23.1" "Kidney - Ascending Loop of Henle cells, Prostate - Prostate glandular cells" "Secreted in other tissues" Hormone NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 9: Non-specific - Receptor signaling" "Cluster 34: Testis cancer - Unknown function" "Cluster 63: Cytotrophoblasts - Basic cellular functions" "unprognostic (2.00e-1)" "unprognostic (1.68e-1)" "unprognostic (1.42e-1)" "unprognostic (2.29e-1)" "unprognostic (2.78e-1)" "unprognostic (3.61e-1)" APEX1 "APE, APE-1, APEN, APEX, APX, HAP1, REF-1, REF1" ENSG00000100823 "Apurinic/apyrimidinic endodeoxyribonuclease 1" P27695 14 20455191-20457772 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation" "Activator, DNA-binding, Endonuclease, Exonuclease, Hydrolase, Nuclease, Repressor, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000956, HPA002564, CAB004294, CAB047307" Supported Supported Nucleoplasm,Centrosome Yes No 220000 "Cluster 30: Non-specific - DNA binding" "Cluster 54: Non-specific - Ribosome" "Cluster 21: Non-specific - Metabolism" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 17: Non-specific - RNA processing" 78 Nucleoplasm Centrosome "CAB004294: , CAB047307: , HPA000956: , HPA002564: " "unprognostic (2.12e-1)" "unprognostic (3.10e-2)" "unprognostic (1.35e-2)" "unprognostic (1.48e-1)" "unprognostic (3.18e-2)" "unprognostic (1.79e-1)" "unprognostic (4.56e-2)" "unprognostic (7.15e-2)" "unprognostic (4.33e-3)" "unprognostic (2.10e-3)" "potential prognostic favorable (8.71e-6)" "unprognostic (4.93e-3)" "unprognostic (1.11e-1)" "validated prognostic unfavorable (1.41e-5)" "validated prognostic unfavorable (8.78e-6)" "unprognostic (2.20e-2)" "unprognostic (2.05e-3)" "unprognostic (1.03e-2)" "unprognostic (1.65e-1)" "unprognostic (5.89e-2)" "unprognostic (1.61e-1)" "unprognostic (4.33e-3)" "unprognostic (3.75e-1)" "unprognostic (2.13e-1)" "unprognostic (2.58e-2)" "unprognostic (1.74e-1)" "unprognostic (2.46e-2)" "unprognostic (5.83e-2)" "unprognostic (2.89e-2)" "unprognostic (3.35e-2)" "potential prognostic favorable (4.23e-4)" APEX2 "APE2, APEXL2, XTH2, ZGRF2" ENSG00000169188 "Apurinic/apyrimidinic endodeoxyribonuclease 2" Q9UBZ4 X 55000363-55009057 "Enzymes, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA recombination, DNA repair" "DNA-binding, Endonuclease, Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 58.0;Extravillous trophoblasts: 40.5;Migrating cytotrophoblasts: 59.5;Syncytiotrophoblasts: 53.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048577 Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles" NA Yes "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 6 "Nucleoplasm, Nucleoli fibrillar center" Vesicles "HPA048577: " "unprognostic (3.21e-1)" "unprognostic (4.73e-2)" "unprognostic (1.30e-1)" "unprognostic (6.27e-2)" "unprognostic (2.55e-1)" "unprognostic (1.13e-1)" "unprognostic (2.20e-1)" "unprognostic (1.86e-1)" "unprognostic (4.99e-1)" "unprognostic (1.03e-2)" "unprognostic (1.25e-2)" "unprognostic (1.62e-2)" "unprognostic (5.84e-2)" "potential prognostic unfavorable (5.05e-7)" "unprognostic (2.92e-3)" "unprognostic (8.06e-3)" "unprognostic (6.72e-3)" "unprognostic (3.93e-2)" "unprognostic (1.75e-2)" "unprognostic (5.02e-3)" "unprognostic (2.81e-2)" "unprognostic (2.46e-2)" "unprognostic (1.48e-2)" "unprognostic (1.11e-1)" "unprognostic (1.77e-1)" "unprognostic (3.62e-2)" "unprognostic (7.31e-2)" "unprognostic (1.17e-1)" "unprognostic (1.81e-1)" "unprognostic (3.34e-1)" "unprognostic (4.72e-2)" APH1A "APH-1A, CGI-78" ENSG00000117362 "Aph-1 homolog A, gamma-secretase subunit" Q96BI3 1 150265399-150269580 "Predicted membrane proteins, Transporters" "Notch signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 374.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB037272 Approved NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 58: Skin - Keratinization" "Cluster 19: Astrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 15: Non-specific - Protein processing" 32 "CAB037272: " "unprognostic (9.66e-2)" "unprognostic (1.09e-1)" "unprognostic (1.02e-1)" "unprognostic (4.54e-3)" "unprognostic (3.34e-2)" "unprognostic (7.79e-2)" "unprognostic (9.44e-2)" "unprognostic (9.28e-2)" "unprognostic (5.65e-2)" "unprognostic (2.17e-1)" "potential prognostic favorable (1.08e-4)" "unprognostic (9.41e-2)" "unprognostic (3.43e-1)" "potential prognostic unfavorable (9.35e-4)" "unprognostic (3.42e-2)" "unprognostic (1.80e-1)" "unprognostic (1.12e-2)" "unprognostic (1.90e-2)" "unprognostic (4.02e-2)" "unprognostic (3.54e-1)" "unprognostic (2.09e-1)" "unprognostic (1.10e-3)" "unprognostic (1.95e-2)" "unprognostic (7.19e-2)" "unprognostic (3.16e-2)" "unprognostic (1.13e-1)" "potential prognostic unfavorable (6.36e-4)" "unprognostic (2.41e-1)" "unprognostic (2.28e-1)" "unprognostic (7.07e-2)" "unprognostic (1.24e-1)" APH1B "APH-1B, DKFZp564D0372, PSFL" ENSG00000138613 "Aph-1 homolog B, gamma-secretase subunit" Q8WW43 15 63276018-63309126 "Predicted membrane proteins, Transporters" "Notch signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "testis: 111.2" "Group enriched" "Detected in many" 5 "Early spermatids: 1354.0;Late primary spermatocytes: 2367.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 108.2" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 47: Testis - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 2 "unprognostic (5.60e-2)" "unprognostic (2.71e-1)" "unprognostic (1.66e-1)" "unprognostic (1.11e-2)" "unprognostic (1.88e-1)" "unprognostic (1.26e-1)" "unprognostic (7.02e-2)" "unprognostic (3.48e-2)" "unprognostic (2.03e-1)" "unprognostic (1.40e-1)" "potential prognostic favorable (6.67e-8)" "unprognostic (1.03e-1)" "potential prognostic favorable (5.37e-4)" "unprognostic (5.51e-3)" "unprognostic (3.19e-3)" "unprognostic (7.34e-2)" "unprognostic (2.16e-2)" "unprognostic (5.71e-2)" "unprognostic (1.50e-1)" "unprognostic (2.48e-2)" "unprognostic (3.69e-3)" "unprognostic (3.36e-2)" "unprognostic (2.39e-2)" "unprognostic (8.26e-2)" "unprognostic (9.35e-2)" "unprognostic (3.10e-1)" "unprognostic (2.57e-1)" "unprognostic (2.47e-3)" "unprognostic (2.84e-1)" "unprognostic (2.52e-1)" "unprognostic (3.77e-1)" API5 "AAC-11, AAC11, API5L1" ENSG00000166181 "Apoptosis inhibitor 5" Q9BZZ5 11 43311963-43344529 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026598 Approved Enhanced "Nuclear speckles" NA NA 120000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 61: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 26 "Nuclear speckles" "HPA026598: " "unprognostic (1.41e-2)" "unprognostic (6.26e-3)" "unprognostic (3.06e-3)" "unprognostic (9.17e-3)" "unprognostic (2.19e-1)" "unprognostic (1.58e-1)" "unprognostic (9.00e-2)" "unprognostic (1.87e-1)" "unprognostic (1.62e-1)" "potential prognostic unfavorable (6.12e-6)" "potential prognostic favorable (5.79e-7)" "unprognostic (2.60e-3)" "unprognostic (1.52e-1)" "unprognostic (1.10e-3)" "unprognostic (2.86e-2)" "unprognostic (2.19e-1)" "unprognostic (4.03e-2)" "unprognostic (1.34e-1)" "unprognostic (2.42e-1)" "unprognostic (1.33e-1)" "unprognostic (1.81e-2)" "unprognostic (1.31e-2)" "unprognostic (1.79e-1)" "unprognostic (4.94e-2)" "potential prognostic favorable (4.60e-4)" "unprognostic (5.44e-2)" "unprognostic (9.99e-2)" "unprognostic (1.00e-1)" "unprognostic (3.57e-1)" "unprognostic (6.24e-2)" "unprognostic (1.52e-2)" APIP "APIP2, CGI-29, Mmrp19" ENSG00000149089 "APAF1 interacting protein" Q96GX9 11 34853094-34916379 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Amino-acid biosynthesis, Apoptosis, Methionine biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Breast lactating cells: 446.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021188, HPA024131" Approved Approved Nucleoplasm,Cytosol NA NA 54000 "Cluster 13: Non-specific - Mitochondria" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 4: Breast lactating luminal cells - Lactation" 29 Nucleoplasm Cytosol "HPA021188: , HPA024131: " "unprognostic (3.52e-2)" "unprognostic (7.76e-2)" "unprognostic (1.83e-1)" "unprognostic (3.03e-2)" "unprognostic (4.00e-2)" "unprognostic (1.13e-1)" "unprognostic (2.01e-3)" "unprognostic (5.13e-3)" "unprognostic (1.46e-1)" "unprognostic (3.13e-1)" "potential prognostic favorable (9.24e-7)" "unprognostic (3.99e-2)" "unprognostic (4.14e-2)" "unprognostic (3.57e-2)" "unprognostic (8.80e-3)" "unprognostic (2.90e-1)" "unprognostic (1.12e-1)" "unprognostic (9.71e-2)" "unprognostic (3.50e-1)" "unprognostic (1.05e-1)" "unprognostic (2.41e-1)" "unprognostic (5.21e-2)" "unprognostic (2.67e-1)" "unprognostic (2.49e-1)" "unprognostic (9.40e-2)" "unprognostic (1.40e-1)" "unprognostic (4.20e-1)" "unprognostic (2.62e-1)" "unprognostic (3.12e-1)" "unprognostic (3.06e-1)" "unprognostic (4.82e-2)" APLF "C2orf13, MGC47799, Xip1, ZCCHH1" ENSG00000169621 "Aprataxin and PNKP like factor" Q8IW19 2 68467572-68655862 "Predicted intracellular proteins" "DNA damage, DNA repair" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Early spermatids: 281.4;Late spermatids: 352.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 7.1" "Lineage enriched" "Detected in many" 5 "granulocytes: 7.1" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034642, HPA034643" Uncertain Supported Nucleoplasm NA NA "Cluster 58: Skin - Keratinization" "Cluster 51: Neurons - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 23 Nucleoplasm "HPA034642: , HPA034643: " "unprognostic (5.40e-2)" "unprognostic (5.55e-2)" "unprognostic (1.25e-1)" "unprognostic (3.10e-3)" "potential prognostic favorable (3.16e-4)" "unprognostic (5.59e-2)" "unprognostic (6.39e-2)" "unprognostic (6.16e-2)" "unprognostic (7.37e-2)" "unprognostic (1.03e-1)" "unprognostic (6.22e-3)" "unprognostic (1.22e-1)" "unprognostic (3.95e-1)" "unprognostic (2.95e-3)" APLN "apelin, XNPEP2" ENSG00000171388 Apelin Q9ULZ1 X 129645259-129654956 "Predicted secreted proteins" "Angiogenesis, Gastrulation, Host-virus interaction" "Developmental protein, Hormone" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 29.4;placenta: 50.8" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 21.3;Astrocytes: 7.7;Breast myoepithelial cells: 12.1;Oligodendrocytes: 4.6;Paneth cells: 3.9;Pituitary stem cells: 20.3;Podocytes: 17.6;Somatotrophs: 10.1;Vascular endothelial cells: 7.2" "Cell type enhanced" "Detected in some" "astrocyte: 12.8;endothelial cell: 6.6;oligodendrocyte: 6.6" "Group enriched" "Detected in all" 5 "Glioblastoma Multiforme (TCGA): 69.2;Kidney Renal Clear Cell Carcinoma (TCGA): 49.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Kidney cancer: 18.8;prostate cancer: 64.5" "Kidney - Podocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted in other tissues" Hormone NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 3 "unprognostic (8.25e-3)" "unprognostic (1.21e-1)" "unprognostic (3.77e-3)" "potential prognostic unfavorable (4.44e-4)" "unprognostic (9.60e-2)" "unprognostic (2.95e-1)" "unprognostic (7.68e-2)" "unprognostic (8.19e-3)" "unprognostic (2.25e-2)" "potential prognostic unfavorable (2.20e-5)" "potential prognostic favorable (8.63e-4)" "unprognostic (3.76e-1)" "unprognostic (1.74e-2)" "unprognostic (1.67e-3)" "unprognostic (8.97e-2)" "unprognostic (2.70e-3)" "unprognostic (2.69e-3)" "unprognostic (5.78e-3)" "unprognostic (3.37e-1)" "unprognostic (1.88e-1)" "unprognostic (2.45e-2)" "unprognostic (3.97e-1)" "unprognostic (2.37e-2)" "unprognostic (3.80e-2)" "unprognostic (2.03e-1)" "unprognostic (4.07e-2)" "unprognostic (7.09e-3)" "unprognostic (3.62e-2)" "unprognostic (1.87e-1)" "unprognostic (2.73e-1)" "unprognostic (1.36e-1)" APLNR "AGTRL1, APJ, APJR, FLJ90771" ENSG00000134817 "Apelin receptor" P35414 11 57233577-57237250 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Angiogenesis, Gastrulation, Host-virus interaction" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 77.5;lymphoid tissue: 101.5;placenta: 87.2" "Group enriched" "Detected in some" 8 "Astrocytes: 21.7;Lymphatic endothelial cells: 19.5;Vascular endothelial cells: 46.8" "Cell type enriched" "Detected in some" 9 "astrocyte: 62.1" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 78.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 8 "Rhabdoid: 24.1" "Skin - Fibroblasts_1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" CAB025842 Approved NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 39: Astrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 88 "CAB025842: " "unprognostic (3.65e-1)" "unprognostic (2.47e-1)" "unprognostic (1.70e-1)" "unprognostic (4.96e-2)" "unprognostic (1.71e-1)" "unprognostic (5.59e-2)" "unprognostic (1.60e-1)" "unprognostic (4.58e-3)" "unprognostic (2.07e-2)" "unprognostic (1.20e-2)" "validated prognostic favorable (2.78e-7)" "validated prognostic favorable (1.26e-4)" "potential prognostic unfavorable (1.57e-4)" "unprognostic (6.44e-3)" "unprognostic (2.11e-3)" "unprognostic (5.70e-2)" "unprognostic (8.93e-2)" "unprognostic (1.25e-1)" "unprognostic (2.44e-1)" "unprognostic (1.07e-1)" "unprognostic (3.71e-3)" "unprognostic (1.05e-1)" "unprognostic (1.05e-3)" "unprognostic (2.55e-1)" "unprognostic (7.12e-2)" "unprognostic (1.31e-1)" "unprognostic (3.22e-1)" "unprognostic (2.81e-2)" "unprognostic (7.17e-2)" "unprognostic (2.38e-1)" "unprognostic (5.88e-2)" APLP1 APLP ENSG00000105290 "Amyloid beta precursor like protein 1" P51693 19 35867899-35879792 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell adhesion, Endocytosis" Heparin-binding Neurodegeneration "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 1120.2" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 159.6;Brain excitatory neurons: 75.7;Brain inhibitory neurons: 90.6;Oligodendrocytes: 626.1;Other brain neurons: 98.5;Pancreatic islet cells: 175.9;Parietal cells: 68.9;Retinal bipolar cells: 110.8;Retinal horizontal cells: 70.1;Retinal pigment epithelial cells: 174.8" "Cell type enhanced" "Detected in all" "oligodendrocyte: 746.7" "Group enriched" "Detected in all" 4 "Glioblastoma Multiforme (TCGA): 169.5;Pancreatic Adenocarcinoma (TCGA): 55.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Rhabdoid: 146.5" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Kidney - Podocytes, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028970, HPA028971" Enhanced Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA 12000000 "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 80: Oligodendrocytes - Myelination" 16 "Golgi apparatus, Plasma membrane" Nucleoplasm "HPA028970: , HPA028971: " "unprognostic (2.39e-1)" "unprognostic (1.48e-2)" "unprognostic (6.70e-3)" "unprognostic (1.46e-1)" "unprognostic (2.66e-1)" "unprognostic (2.67e-1)" "unprognostic (1.53e-2)" "unprognostic (5.34e-2)" "unprognostic (3.61e-2)" "unprognostic (9.76e-3)" "validated prognostic unfavorable (6.21e-5)" "validated prognostic unfavorable (6.83e-5)" "potential prognostic unfavorable (3.17e-5)" "potential prognostic unfavorable (6.94e-4)" "unprognostic (1.04e-1)" "unprognostic (1.07e-1)" "unprognostic (1.68e-1)" "unprognostic (5.13e-2)" "unprognostic (2.96e-2)" "unprognostic (4.70e-2)" "unprognostic (1.07e-1)" "unprognostic (1.45e-2)" "unprognostic (1.24e-1)" "unprognostic (6.69e-2)" "unprognostic (1.03e-1)" "unprognostic (2.02e-1)" "unprognostic (1.05e-1)" "unprognostic (1.31e-2)" "unprognostic (3.10e-1)" "unprognostic (6.05e-3)" "unprognostic (7.83e-2)" APLP2 "APPH, APPL2" ENSG00000084234 "Amyloid beta precursor like protein 2" Q06481 11 130068147-130144811 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "DNA-binding, Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 1391.0;Retinal pigment epithelial cells: 1364.1;Syncytiotrophoblasts: 1146.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 249.2" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Lung - Alveolar cells type 1, Spleen - Fibroblasts_2, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039319 Approved Approved "Golgi apparatus,Vesicles" NA NA 3200000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 20 "Golgi apparatus, Vesicles" "HPA039319: " "unprognostic (4.54e-1)" "unprognostic (4.61e-3)" "unprognostic (3.01e-1)" "unprognostic (3.95e-3)" "unprognostic (9.95e-3)" "unprognostic (1.33e-2)" "unprognostic (5.12e-2)" "potential prognostic unfavorable (3.38e-4)" "unprognostic (1.03e-2)" "unprognostic (9.68e-3)" "potential prognostic favorable (9.06e-6)" "unprognostic (3.34e-2)" "potential prognostic favorable (8.17e-4)" "potential prognostic unfavorable (3.66e-4)" "unprognostic (3.66e-3)" "unprognostic (1.48e-1)" "unprognostic (5.02e-3)" "unprognostic (4.54e-3)" "unprognostic (2.34e-1)" "unprognostic (4.01e-1)" "unprognostic (1.50e-1)" "unprognostic (4.28e-3)" "unprognostic (2.39e-2)" "unprognostic (9.60e-2)" "unprognostic (3.86e-2)" "unprognostic (1.08e-1)" "unprognostic (2.04e-1)" "unprognostic (1.17e-2)" "unprognostic (6.51e-2)" "unprognostic (4.11e-3)" "unprognostic (6.80e-2)" APMAP "BSCv, C20orf3" ENSG00000101474 "Adipocyte plasma membrane associated protein" Q9HDC9 20 24962925-24992751 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 302.7" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 391.8;Hepatocytes: 276.4;Migrating cytotrophoblasts: 243.3;Neutrophil progenitors: 452.9;Neutrophils: 404.5;Syncytiotrophoblasts: 1001.3" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 206.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "granulocytes: 682.8;NK-cells: 344.4;T-cells: 368.6" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Lung - Neutrophils_2, Pituitary gland - Corticotropes, Skin - Sebaceous gland cells, Spleen - Neutrophils_2, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012863, HPA064700" Approved Approved "Plasma membrane" NA NA 110000000 "Cluster 35: Neutrophils - Protein binding" "Cluster 36: Brain & Liver - Signaling" "Cluster 25: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 13 "Plasma membrane" "HPA012863: , HPA064700: " "unprognostic (1.01e-1)" "unprognostic (1.80e-3)" "unprognostic (2.06e-2)" "unprognostic (1.48e-1)" "unprognostic (7.67e-2)" "unprognostic (1.43e-1)" "unprognostic (5.35e-2)" "unprognostic (8.99e-3)" "unprognostic (1.00e-1)" "unprognostic (2.57e-3)" "unprognostic (1.87e-3)" "unprognostic (2.52e-1)" "unprognostic (1.83e-2)" "unprognostic (5.03e-2)" "unprognostic (3.47e-3)" "unprognostic (1.52e-1)" "unprognostic (5.70e-2)" "unprognostic (3.92e-3)" "unprognostic (8.52e-2)" "unprognostic (7.68e-2)" "unprognostic (5.41e-1)" "unprognostic (3.39e-1)" "unprognostic (1.55e-1)" "unprognostic (1.65e-2)" "unprognostic (9.59e-2)" "unprognostic (1.94e-1)" "unprognostic (3.16e-1)" "unprognostic (2.97e-2)" "unprognostic (1.09e-1)" APOA1 ENSG00000118137 "Apolipoprotein A1" P02647 11 116835751-116837622 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" "Amyloidosis, Atherosclerosis, Cancer-related genes, Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 20151.0" "Group enriched" "Detected in many" 46 "Enterocytes: 17976.9;Hepatocytes: 33105.7" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in many" 41 "Liver Hepatocellular Carcinoma (TCGA): 9842.8" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.2" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 14 "Gastric cancer: 176.6;liver cancer: 494.9" "Liver - Hepatocytes, Testis - Sertoli cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB016778, HPA046715" Supported Approved Vesicles,Cytosol "Secreted to blood" Apolipoprotein NA NA 1450000000000 160000000000 "Cluster 53: Liver - Plasma proteins" "Cluster 34: Non-specific - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 93: Hepatocytes - Bile production & excretion" 47 Vesicles Cytosol "CAB016778: , HPA046715: " "unprognostic (2.84e-1)" "unprognostic (2.57e-1)" "unprognostic (3.86e-3)" "unprognostic (2.44e-3)" "unprognostic (1.18e-1)" "unprognostic (1.90e-3)" "unprognostic (1.21e-2)" "unprognostic (2.77e-2)" "unprognostic (1.51e-1)" "unprognostic (2.88e-2)" "unprognostic (1.23e-2)" "potential prognostic favorable (4.92e-4)" "unprognostic (1.34e-1)" "unprognostic (1.58e-2)" "unprognostic (1.65e-1)" "unprognostic (8.08e-3)" "unprognostic (1.30e-1)" "unprognostic (2.59e-2)" "unprognostic (3.68e-2)" APOA2 ENSG00000158874 "Apolipoprotein A2" P02652 1 161222292-161223631 "Cancer-related genes, Candidate cardiovascular disease genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Host-virus interaction, Lipid transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1359 "liver: 33506.8" "Cell type enriched" "Detected in some" 164 "Hepatocytes: 52172.4" "Cell type enriched" "Detected in single" 4 "hippocampal dentate gyrus: 1.3" "Cancer enriched" "Detected in many" 314 "Liver Hepatocellular Carcinoma (TCGA): 39828.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 9 "liver cancer: 2178.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025885, HPA072575" Supported "Secreted to blood" Apolipoprotein NA NA 115000000000 35000000000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 12: Non-specific - Vasculature" "Cluster 18: Liver cancer - Metabolism" "Cluster 93: Hepatocytes - Bile production & excretion" 27 "CAB025885: , HPA072575: " "unprognostic (1.47e-1)" "unprognostic (6.59e-2)" "unprognostic (4.00e-1)" "unprognostic (5.35e-2)" "unprognostic (6.78e-2)" "unprognostic (8.81e-2)" "unprognostic (1.74e-1)" "unprognostic (4.52e-2)" "unprognostic (2.91e-1)" "unprognostic (1.34e-1)" "unprognostic (1.72e-2)" "unprognostic (7.80e-1)" "unprognostic (1.82e-1)" "unprognostic (1.44e-1)" "unprognostic (1.19e-1)" "unprognostic (4.07e-3)" "unprognostic (2.31e-1)" "unprognostic (4.82e-2)" "unprognostic (6.03e-1)" APOA4 ENSG00000110244 "Apolipoprotein A4" P06727 11 116820700-116823304 "Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Lipid transport, Transport" "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "intestine: 2929.9" "Cell type enriched" "Detected in some" 65 "Enterocytes: 10360.3" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 24 "Liver Hepatocellular Carcinoma (TCGA): 368.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "liver cancer: 3.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001352, HPA002549, CAB068250, CAB068251, CAB068252" Enhanced Approved Vesicles "Secreted to blood" Apolipoprotein NA NA 61200000000 53000000000 "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 34: Testis cancer - Unknown function" "Cluster 1: Enterocytes - Absorption and Digestion" 7 Vesicles "CAB068250: , CAB068251: , CAB068252: , HPA001352: , HPA002549: " "unprognostic (1.32e-1)" "unprognostic (3.67e-1)" "unprognostic (1.59e-2)" "unprognostic (1.35e-3)" "unprognostic (1.17e-2)" "unprognostic (6.71e-2)" APOA5 "APOA-V, RAP3" ENSG00000110243 "Apolipoprotein A5" Q6Q788 11 116789367-116792420 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Lipid transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 227 "liver: 568.8" "Cell type enriched" "Detected in some" 387 "Hepatocytes: 1587.6" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 309 "Liver Hepatocellular Carcinoma (TCGA): 169.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 18 "liver cancer: 2.7" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" Apolipoprotein NA NA 114000000 16000000 "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 18: Liver cancer - Metabolism" "Cluster 93: Hepatocytes - Bile production & excretion" 12 "unprognostic (8.97e-3)" "potential prognostic favorable (9.05e-4)" APOB ENSG00000084674 "Apolipoprotein B" P04114 2 21001429-21044073 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" Heparin-binding "Atherosclerosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 143 "intestine: 286.7;liver: 1114.1" "Group enriched" "Detected in some" 7 "Enterocytes: 1716.3;Hepatocytes: 3326.2" "Cell type enriched" "Detected in some" 11 "fibroblast: 14.7" "Cancer enriched" "Detected in some" 80 "Liver Hepatocellular Carcinoma (TCGA): 362.3" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 13 "liver cancer: 178.6" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Prostate - Smooth muscle cells, Spleen - Fibroblasts_2" "Not detected" "Not detected" "Not detected" "Not detected" "CAB016070, HPA049793, CAB080297, CAB080298, CAB080299" Supported Supported Vesicles,Cytosol "Secreted to blood" Apolipoprotein NA NA 1490000000000 250000000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 39: Astrocytes - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 39 "Vesicles, Cytosol" "CAB016070: , CAB080297: , CAB080298: , CAB080299: , HPA049793: " "unprognostic (1.15e-1)" "unprognostic (9.11e-3)" "unprognostic (6.55e-2)" "unprognostic (1.24e-2)" "unprognostic (1.04e-1)" "unprognostic (3.64e-1)" "unprognostic (2.18e-1)" "unprognostic (1.05e-2)" "unprognostic (2.98e-1)" APOBEC1 "APOBEC-1, BEDP, CDAR1, HEPR" ENSG00000111701 "Apolipoprotein B mRNA editing enzyme catalytic subunit 1" P41238 12 7649400-7665908 "Enzymes, Predicted intracellular proteins" "mRNA processing" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 25 "intestine: 27.3" "Cell type enriched" "Detected in some" 7 "Enterocytes: 161.8" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Colon Adenocarcinoma (TCGA): 2.9;Pancreatic Adenocarcinoma (TCGA): 2.9;Rectum Adenocarcinoma (TCGA): 2.5;Stomach Adenocarcinoma (TCGA): 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "colorectal cancer: 1.4" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 1: Enterocytes - Absorption and Digestion" 10 "unprognostic (1.94e-1)" "unprognostic (1.43e-1)" "unprognostic (1.62e-3)" "unprognostic (7.42e-2)" "unprognostic (2.02e-2)" "unprognostic (1.56e-1)" "unprognostic (1.38e-1)" APOBEC2 "ARCD1, ARP1" ENSG00000124701 "Apolipoprotein B mRNA editing enzyme catalytic subunit 2" Q9Y235 6 41053202-41064891 "Enzymes, Predicted intracellular proteins" "mRNA processing" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 141.9;skeletal muscle: 799.8;tongue: 268.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 121.6;Extravillous trophoblasts: 29.5;Late primary spermatocytes: 34.4;Late spermatids: 32.5;Myonuclei: 107.7;Pancreatic duct cells: 35.1;Parietal cells: 166.2;Thymic myoid cells: 159.1" "Cell type enhanced" "Detected in many" "Bergmann glia: 10.4;choroid plexus epithelial cell: 10.3" "Cancer enhanced" "Detected in some" "Head and Neck Squamous Cell Carcinoma (TCGA): 4.1;Pancreatic Adenocarcinoma (TCGA): 5.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in single" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA014252, HPA017957" Enhanced Supported Nucleoplasm NA NA 9100 "Cluster 14: Non-specific - Unknown function" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 11: White matter - Signal transduction" "Cluster 1: Neuronal - Visual perception" "Cluster 46: Skeletal myocytes - Muscle structure & formation" Nucleoplasm "HPA014252: , HPA017957: " "unprognostic (2.26e-1)" "unprognostic (1.92e-2)" "unprognostic (1.48e-1)" "unprognostic (1.34e-1)" "unprognostic (1.19e-2)" "unprognostic (1.26e-1)" "unprognostic (1.47e-1)" "unprognostic (8.04e-2)" APOBEC3A "ARP3, PHRBN" ENSG00000128383 "Apolipoprotein B mRNA editing enzyme catalytic subunit 3A" P31941 22 38952741-38992778 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 88.5;lymphoid tissue: 47.9" "Cell type enriched" "Detected in some" 8 "Ocular epithelial cells: 3390.0" "Group enriched" "Detected in some" 4 "hippocampal CA4: 7.4;leukocyte: 9.8" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 33.3;Head and Neck Squamous Cell Carcinoma (TCGA): 49.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 1008.2" "Lineage enriched" "Detected in many" 8 "monocytes: 1008.2" "Cancer enriched" "Detected in single" 9 "head and neck cancer: 5.4" "Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophils_2, Pituitary gland - Neutrophils, Skeletal muscle - Neutrophils, Spleen - Neutrophils_2, Stomach - Neutrophils" "HPA043237, HPA056980, HPA066719" Approved Uncertain Nucleoplasm NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 4 Nucleoplasm "HPA043237: , HPA056980: , HPA066719: " "unprognostic (1.13e-1)" "unprognostic (9.01e-2)" "unprognostic (8.40e-2)" "unprognostic (1.28e-2)" "unprognostic (2.78e-1)" "unprognostic (1.38e-3)" "unprognostic (2.64e-2)" "unprognostic (4.41e-2)" "potential prognostic unfavorable (1.24e-4)" "unprognostic (2.88e-1)" "potential prognostic unfavorable (2.37e-4)" "unprognostic (3.56e-1)" "unprognostic (2.53e-1)" "unprognostic (1.95e-1)" "unprognostic (4.41e-2)" "unprognostic (3.01e-3)" "unprognostic (1.69e-2)" "unprognostic (9.53e-3)" "unprognostic (1.12e-2)" "unprognostic (3.40e-2)" "unprognostic (1.85e-1)" "unprognostic (1.22e-1)" "unprognostic (8.78e-2)" "unprognostic (3.85e-2)" "unprognostic (1.28e-1)" "potential prognostic unfavorable (3.75e-4)" APOBEC3B "FLJ21201, PHRBNL" ENSG00000179750 "Apolipoprotein B mRNA editing enzyme catalytic subunit 3B" Q9UH17 22 38982347-38992804 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" "Hydrolase, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 26.8;intestine: 11.3" "Cell type enhanced" "Detected in some" "Breast secretory cells: 2.8;Endometrial glandular cells: 2.3;Endometrial secretory cells: 8.4;Epididymal basal cells: 5.0;Epididymal efferent duct ciliated cells: 3.8;Erythrocyte progenitors: 5.9;Megakaryocyte progenitors: 4.6;Migrating cytotrophoblasts: 2.2;Monocyte progenitors: 4.7;Ocular epithelial cells: 4.9;Pancreatic duct cells: 2.9;Plasma cells: 4.9" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "memory B-cell: 7.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach)" "HPA056980, HPA066719" Supported Nucleoplasm NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 6 Nucleoplasm "HPA056980: , HPA066719: " "unprognostic (4.27e-2)" "unprognostic (4.94e-2)" "unprognostic (2.85e-1)" "potential prognostic favorable (5.56e-5)" "unprognostic (1.69e-1)" "unprognostic (1.03e-2)" "unprognostic (2.08e-1)" "unprognostic (2.64e-2)" "unprognostic (1.43e-1)" "unprognostic (4.51e-3)" "validated prognostic unfavorable (7.06e-4)" "validated prognostic unfavorable (7.16e-4)" "potential prognostic unfavorable (6.07e-4)" "unprognostic (7.76e-3)" "potential prognostic unfavorable (1.16e-5)" "unprognostic (3.15e-2)" "potential prognostic unfavorable (5.42e-5)" "unprognostic (5.19e-2)" "unprognostic (1.74e-1)" "unprognostic (5.01e-2)" "unprognostic (2.88e-1)" "unprognostic (1.31e-2)" "unprognostic (3.22e-1)" "unprognostic (3.18e-2)" "unprognostic (1.43e-1)" "unprognostic (1.11e-2)" "unprognostic (5.94e-2)" "unprognostic (1.45e-1)" "unprognostic (2.87e-1)" "unprognostic (1.40e-1)" "unprognostic (1.63e-2)" APOBEC3C "APOBEC1L, ARDC2, ARDC4, ARP5, bK150C2.3, PBI" ENSG00000244509 "Apolipoprotein B mRNA editing enzyme catalytic subunit 3C" Q9NRW3 22 39014257-39020352 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Erythrocyte progenitors: 6.5;Megakaryocyte progenitors: 3.8;Megakaryocyte-Erythroid progenitors: 4.7;Microglia: 9.3;NK-cells: 5.0;Oligodendrocyte progenitor cells: 3.9;Plasma cells: 3.3;Platelets: 5.7;T-cells: 3.2" "Cell type enriched" "Detected in some" 4 "leukocyte: 53.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells, Skeletal muscle - Fibroblasts, Testis - Sertoli cells" "CAB033048, HPA071523" Approved Approved "Intermediate filaments" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 102: Non-specific - Mixed function" 41 "Intermediate filaments" "CAB033048: , HPA071523: " "unprognostic (9.87e-2)" "unprognostic (4.66e-3)" "unprognostic (1.97e-1)" "unprognostic (4.13e-2)" "unprognostic (5.22e-2)" "unprognostic (9.52e-3)" "unprognostic (4.29e-2)" "potential prognostic unfavorable (1.31e-5)" "unprognostic (3.25e-1)" "unprognostic (6.01e-2)" "unprognostic (1.62e-3)" "unprognostic (9.79e-2)" "unprognostic (5.64e-2)" "unprognostic (1.26e-1)" "unprognostic (1.63e-1)" "unprognostic (1.99e-2)" "unprognostic (2.27e-3)" "unprognostic (4.36e-2)" "unprognostic (2.38e-1)" "unprognostic (1.19e-2)" "unprognostic (2.91e-1)" "unprognostic (3.74e-2)" "unprognostic (1.76e-2)" "unprognostic (7.86e-2)" "unprognostic (1.68e-1)" "unprognostic (5.31e-2)" "unprognostic (1.16e-1)" "unprognostic (1.21e-1)" "unprognostic (7.82e-2)" "unprognostic (9.77e-2)" "unprognostic (3.56e-1)" APOBEC3D "APOBEC3DE, APOBEC3E, ARP6" ENSG00000243811 "Apolipoprotein B mRNA editing enzyme catalytic subunit 3D" Q96AK3 22 39021113-39033277 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 14.3" "Cell type enhanced" "Detected in some" "B-cells: 1.9;Ependymal cells: 2.7;Epididymal basal cells: 1.4;Epididymal clear cells: 2.0;Gastric chief cells: 3.3;Microglia: 1.7;NK-cells: 1.7;Parietal cells: 5.3;Respiratory ionocytes: 2.5;Sertoli cells: 1.4;T-cells: 2.3" "Cell type enriched" "Detected in some" 4 "leukocyte: 28.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Myeloma: 13.1" "Breast - T-cells, Liver - T-cells, Minor Salivary Gland - T-cells, Thyroid gland - T-cells" HPA055116 Approved NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 25: Non-specific - Transcription" "Cluster 59: Leukemia - T-cell receptor" "Cluster 102: Non-specific - Mixed function" 77 "HPA055116: " "unprognostic (1.85e-1)" "potential prognostic favorable (4.90e-4)" "unprognostic (7.23e-2)" "unprognostic (2.68e-1)" "unprognostic (5.06e-2)" "unprognostic (3.59e-2)" "unprognostic (9.56e-3)" "potential prognostic unfavorable (6.03e-5)" "unprognostic (7.72e-2)" "unprognostic (6.82e-2)" "potential prognostic unfavorable (1.94e-4)" "unprognostic (1.01e-1)" "unprognostic (1.86e-2)" "unprognostic (1.28e-1)" "unprognostic (1.34e-1)" "unprognostic (4.88e-2)" "unprognostic (3.08e-1)" "unprognostic (3.80e-1)" "unprognostic (1.48e-1)" "unprognostic (5.64e-2)" "unprognostic (1.25e-2)" "unprognostic (3.30e-2)" "unprognostic (1.19e-1)" "unprognostic (1.65e-1)" "unprognostic (2.03e-1)" "unprognostic (1.04e-1)" "unprognostic (1.57e-1)" "unprognostic (2.27e-2)" "unprognostic (6.94e-2)" "unprognostic (3.67e-1)" "unprognostic (8.10e-3)" APOBEC3F "ARP8, BK150C2.4.MRNA, KA6" ENSG00000128394 "Apolipoprotein B mRNA editing enzyme catalytic subunit 3F" Q8IUX4 22 39040604-39055972 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 8.7;leukocyte: 18.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - T-cells" HPA073637 Uncertain Nucleoplasm,Cytosol NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 26 "Nucleoplasm, Cytosol" "HPA073637: " "unprognostic (1.05e-1)" "unprognostic (1.77e-2)" "unprognostic (4.31e-1)" "unprognostic (7.80e-2)" "unprognostic (1.46e-1)" "unprognostic (4.99e-2)" "unprognostic (1.01e-2)" "potential prognostic unfavorable (4.23e-7)" "unprognostic (1.22e-1)" "unprognostic (2.68e-3)" "potential prognostic unfavorable (8.12e-4)" "unprognostic (5.97e-2)" "unprognostic (6.91e-3)" "unprognostic (2.70e-2)" "unprognostic (1.07e-1)" "unprognostic (7.70e-3)" "unprognostic (1.80e-1)" "unprognostic (4.43e-2)" "unprognostic (4.79e-3)" "unprognostic (8.83e-2)" "unprognostic (3.65e-1)" "unprognostic (4.88e-2)" "unprognostic (5.93e-3)" "unprognostic (1.84e-1)" "unprognostic (1.87e-1)" "unprognostic (8.08e-2)" "unprognostic (5.87e-2)" "unprognostic (7.79e-2)" "unprognostic (4.62e-2)" "unprognostic (4.36e-2)" "unprognostic (1.35e-1)" APOBEC3G "bK150C2.7, CEM15, dJ494G10.1, FLJ12740, MDS019" ENSG00000239713 "Apolipoprotein B mRNA editing enzyme catalytic subunit 3G" Q9HC16 22 39077067-39087743 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 43.0" "Cell type enhanced" "Detected in many" "B-cells: 40.0;Early spermatids: 49.6;Hofbauer cells: 39.8;Innate lymphoid cells: 45.7;Megakaryocytes: 43.3;NK-cells: 166.4;Plasma cells: 81.9;Sertoli cells: 60.8;T-cells: 103.7" "Cell type enriched" "Detected in some" 4 "leukocyte: 72.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Bile duct cancer: 57.4" "Breast - T-cells, Lung - T-cells, Testis - Sertoli cells, Thyroid gland - T-cells" "HPA001812, HPA073637" Enhanced Uncertain Nucleoplasm,Cytosol NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 39: Astrocytes - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 6 "Nucleoplasm, Cytosol" "HPA001812: , HPA073637: " "unprognostic (1.82e-1)" "potential prognostic favorable (3.19e-4)" "unprognostic (1.84e-1)" "potential prognostic favorable (3.36e-4)" "unprognostic (6.11e-2)" "unprognostic (3.27e-1)" "unprognostic (1.33e-1)" "potential prognostic unfavorable (2.43e-4)" "unprognostic (1.35e-1)" "unprognostic (5.80e-2)" "unprognostic (1.59e-2)" "unprognostic (1.14e-1)" "unprognostic (6.49e-3)" "unprognostic (2.89e-1)" "unprognostic (1.03e-2)" "unprognostic (1.26e-1)" "unprognostic (2.62e-1)" "unprognostic (3.18e-1)" "unprognostic (1.10e-1)" "unprognostic (5.43e-2)" "unprognostic (1.82e-1)" "unprognostic (4.46e-3)" "potential prognostic unfavorable (1.89e-4)" "unprognostic (1.41e-1)" "unprognostic (6.50e-2)" "unprognostic (1.30e-1)" "unprognostic (4.95e-1)" "unprognostic (1.30e-1)" "unprognostic (1.22e-2)" "unprognostic (1.12e-1)" "unprognostic (4.12e-2)" APOBEC3H ARP10 ENSG00000100298 "Apolipoprotein B mRNA editing enzyme catalytic subunit 3H" Q6NTF7 22 39097224-39104067 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 7.9;Epididymal principal cells: 3.7;Hofbauer cells: 9.8;Migrating cytotrophoblasts: 6.5;NK-cells: 13.4;Plasma cells: 4.7;Retinal bipolar cells: 4.7;T-cells: 14.7;Thymocytes: 5.1" "Cell type enriched" "Detected in single" 7 "leukocyte: 6.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 9 "gdT-cell: 23.2;MAIT T-cell: 9.4;memory CD4 T-cell: 12.1;memory CD8 T-cell: 19.4;naive CD8 T-cell: 8.9;NK-cell: 19.8;T-reg: 12.0" "Group enriched" "Detected in many" 13 "NK-cells: 19.8;T-cells: 23.2" "Group enriched" "Detected in some" 4 "Leukemia: 6.5;lymphoma: 6.4;Myeloma: 5.6" "Adipose visceral - T-cells, Breast - T-cells, Liver - T-cells, Lung - T-cells, Minor Salivary Gland - T-cells, Prostate - T-cells, Testis - Sertoli cells, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA021492, HPA058565" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 1: T-cells - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 15: Non-specific - Transcription" "Cluster 55: Lymphoma - Immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" Nucleoplasm Cytosol "HPA021492: , HPA058565: " "unprognostic (3.55e-2)" "unprognostic (1.51e-3)" "unprognostic (5.27e-2)" "unprognostic (3.08e-3)" "unprognostic (4.05e-1)" "unprognostic (1.62e-2)" "potential prognostic unfavorable (7.72e-4)" "unprognostic (2.03e-1)" "unprognostic (9.47e-2)" "potential prognostic favorable (6.67e-5)" "unprognostic (3.44e-3)" "unprognostic (1.95e-2)" "unprognostic (3.98e-1)" "unprognostic (1.60e-1)" "unprognostic (4.81e-2)" "unprognostic (5.21e-2)" "unprognostic (8.93e-2)" "unprognostic (6.17e-2)" "unprognostic (9.01e-2)" "unprognostic (2.19e-2)" "unprognostic (1.59e-3)" "unprognostic (1.57e-1)" APOBEC4 "C1orf169, FLJ25691, MGC26594, RP1-127C7.4" ENSG00000173627 "Apolipoprotein B mRNA editing enzyme catalytic polypeptide like 4" Q8WW27 1 183646275-183653316 "Metabolic proteins, Predicted intracellular proteins" "mRNA processing" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "fallopian tube: 10.9;testis: 9.3" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 28.8;Early spermatids: 143.5;Endometrial ciliated cells: 30.7;Epididymal efferent duct ciliated cells: 31.1;Fallopian tube ciliated cells: 87.6;Late primary spermatocytes: 88.8;Late spermatids: 116.2;Respiratory ciliated cells: 65.2" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in single" "Uterine Corpus Endometrial Carcinoma (TCGA): 1.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 29: Forebrain - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 107: Ciliated cells - Cilia assembly & function" 2 "unprognostic (3.00e-1)" APOBR "APOB100R, APOB48R" ENSG00000184730 "Apolipoprotein B receptor" Q0VD83 16 28494643-28498964 "Predicted intracellular proteins" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" Receptor Atherosclerosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 32.7;intestine: 24.9;lung: 11.1;lymphoid tissue: 35.2" "Cell type enhanced" "Detected in some" "cDC: 32.5;Colonocytes: 111.2;Goblet cells: 55.4;Hofbauer cells: 33.9;Macrophages: 29.7;Monocyte progenitors: 44.6;monocytes: 54.3;Neutrophil progenitors: 54.6;Neutrophils: 261.5;NK-cells: 32.3;Tuft cells: 46.1" "Group enriched" "Detected in some" 24 "central nervous system macrophage: 10.5;leukocyte: 26.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in some" 7 "Leukemia: 27.3" "Adipose subcutaneous - Macrophages, Adrenal gland - Macrophages, Skin - Langerhans cells, Spleen - Neutrophils_2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA041667, HPA042093, HPA079642" Enhanced Supported "Plasma membrane,Centrosome" NA NA 270000 "Cluster 21: Neutrophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" "Plasma membrane" Centrosome "HPA041667: , HPA042093: , HPA079642: " "unprognostic (2.65e-2)" "unprognostic (3.50e-1)" "unprognostic (4.47e-2)" "unprognostic (4.42e-2)" "unprognostic (4.53e-3)" "unprognostic (1.28e-1)" "unprognostic (1.97e-3)" "unprognostic (9.85e-3)" "unprognostic (9.86e-2)" "unprognostic (2.51e-2)" "unprognostic (3.76e-1)" "unprognostic (3.87e-3)" "unprognostic (1.13e-1)" "unprognostic (2.09e-2)" "unprognostic (1.51e-2)" "unprognostic (4.92e-2)" "unprognostic (3.63e-1)" "unprognostic (8.86e-2)" "unprognostic (2.51e-2)" "unprognostic (1.71e-1)" "unprognostic (2.37e-2)" "unprognostic (2.59e-2)" "unprognostic (9.50e-2)" "unprognostic (3.34e-1)" "potential prognostic unfavorable (3.84e-4)" "unprognostic (3.05e-3)" "unprognostic (1.01e-1)" "unprognostic (6.64e-3)" "unprognostic (1.09e-1)" "unprognostic (1.01e-1)" APOC1 ENSG00000130208 "Apolipoprotein C1" P02654 19 44914247-44919349 "Cancer-related genes, Candidate cardiovascular disease genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Lipid transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "liver: 18659.9" "Cell type enriched" "Detected in many" 40 "Hepatocytes: 34885.9" "Group enriched" "Detected in many" 6 "astrocyte: 54.1;central nervous system macrophage: 105.4" "Cancer enriched" "Detected in all" 15 "Liver Hepatocellular Carcinoma (TCGA): 13713.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "myeloid DC: 5.9" "Lineage enriched" "Detected in single" 14 "dendritic cells: 5.9" "Cancer enhanced" "Detected in all" "Leukemia: 273.6;liver cancer: 289.3" "Liver - Hepatocytes, Lung - Macrophages, Minor Salivary Gland - Macrophages, Skin - Sebaceous gland cells, Spleen - Macrophages" "Low region specificity" "Detected in all" HPA051518 Supported "Secreted to blood" Apolipoprotein NA NA 20300000000 9900000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 53: Liver - Plasma proteins" "Cluster 21: Non-specific - Metabolism" "Cluster 47: Leukemia - Hemostasis" "Cluster 93: Hepatocytes - Bile production & excretion" 25 "HPA051518: " "unprognostic (3.27e-1)" "unprognostic (8.16e-2)" "unprognostic (2.91e-1)" "unprognostic (4.72e-3)" "unprognostic (2.51e-2)" "unprognostic (2.81e-2)" "unprognostic (2.14e-1)" "unprognostic (7.88e-2)" "unprognostic (2.89e-1)" "unprognostic (1.47e-2)" "unprognostic (7.54e-3)" "unprognostic (3.19e-2)" "unprognostic (1.61e-2)" "validated prognostic favorable (1.08e-7)" "validated prognostic favorable (1.01e-5)" "unprognostic (3.15e-2)" "unprognostic (1.97e-3)" "unprognostic (1.02e-1)" "unprognostic (6.52e-2)" "unprognostic (1.38e-1)" "unprognostic (2.50e-1)" "unprognostic (2.80e-2)" "unprognostic (1.69e-1)" "unprognostic (1.94e-1)" "unprognostic (5.92e-3)" "unprognostic (4.60e-2)" "unprognostic (1.51e-1)" "unprognostic (2.06e-3)" "unprognostic (9.45e-2)" "unprognostic (2.58e-3)" "unprognostic (1.49e-1)" APOC2 ENSG00000234906 "Apolipoprotein C2" P02655 19 44946035-44949565 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism, Lipid transport, Transport" "Disease variant, Hyperlipidemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 115 "liver: 8987.5" "Cell type enriched" "Detected in some" 41 "Microglia: 296.3" "Cell type enriched" "Detected in some" 47 "central nervous system macrophage: 326.4" "Cancer enriched" "Detected in all" 21 "Liver Hepatocellular Carcinoma (TCGA): 6709.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 29 "NK-cell: 3.2" "Lineage enriched" "Detected in single" 29 "NK-cells: 3.2" "Cancer enhanced" "Detected in many" "Brain cancer: 55.3;Leukemia: 80.3;liver cancer: 81.2" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Macrophages" "Not detected" "Not detected" "Not detected" "Not detected" HPA055877 Supported "Secreted to blood" Apolipoprotein NA NA 43000000000 8800000000 "Cluster 14: Non-specific - Unknown function" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 70: DU4475 - Unknown function" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 3 "HPA055877: " "unprognostic (1.18e-1)" "unprognostic (1.07e-1)" "unprognostic (1.47e-2)" "unprognostic (1.31e-1)" "unprognostic (8.80e-2)" "unprognostic (3.40e-2)" "unprognostic (1.20e-1)" "unprognostic (4.55e-1)" "unprognostic (1.53e-1)" "unprognostic (1.00e-1)" "potential prognostic unfavorable (3.53e-4)" "unprognostic (2.54e-2)" "unprognostic (1.20e-1)" "unprognostic (1.27e-2)" "potential prognostic favorable (7.01e-4)" "unprognostic (4.04e-2)" "unprognostic (1.33e-1)" "unprognostic (2.99e-1)" "unprognostic (5.23e-1)" "unprognostic (1.87e-1)" "unprognostic (1.96e-1)" "unprognostic (4.00e-1)" "unprognostic (3.70e-2)" "unprognostic (3.21e-2)" "unprognostic (7.96e-2)" "unprognostic (4.37e-2)" "unprognostic (1.05e-1)" "unprognostic (2.85e-2)" "unprognostic (1.60e-2)" APOC3 "Apo-C3, Apo-CIII, ApoC-3, ApoC-III, APOCIII" ENSG00000110245 "Apolipoprotein C3" P02656 11 116829706-116833072 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism, Lipid transport, Transport" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 25 "liver: 28690.9" "Cell type enriched" "Detected in some" 9 "Hepatocytes: 97065.8" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 453 "Liver Hepatocellular Carcinoma (TCGA): 11879.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "liver cancer: 40.4" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA065365, HPA073918" Supported Approved "Nucleoplasm,Nucleoli,Cell Junctions" "Secreted to blood" Apolipoprotein NA NA 106000000000 16000000000 "Cluster 53: Liver - Plasma proteins" "Cluster 18: Liver cancer - Metabolism" "Cluster 93: Hepatocytes - Bile production & excretion" 8 Nucleoplasm "Nucleoli, Cell Junctions" "HPA065365: , HPA073918: " "unprognostic (7.06e-1)" "unprognostic (7.88e-2)" "unprognostic (2.55e-3)" "unprognostic (3.22e-1)" "validated prognostic favorable (3.08e-4)" "validated prognostic favorable (2.30e-4)" "unprognostic (1.55e-1)" "unprognostic (1.11e-1)" "unprognostic (4.06e-1)" "unprognostic (2.96e-3)" "unprognostic (4.05e-2)" APOC4 ENSG00000267467 "Apolipoprotein C4" P55056 19 44942237-44945496 "Plasma proteins, Predicted secreted proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 506 "liver: 585.9" "Cell type enriched" "Detected in some" 7 "Hepatocytes: 22.4" "Cell type enhanced" "Detected in some" "astrocyte: 1.3;central nervous system macrophage: 3.8" "Cancer enriched" "Detected in some" 95 "Liver Hepatocellular Carcinoma (TCGA): 478.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA062671 Approved "Secreted to blood" Apolipoprotein NA NA 1000000000 600000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 53: Liver - Plasma proteins" "Cluster 34: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 93: Hepatocytes - Bile production & excretion" 22 "HPA062671: " "unprognostic (2.67e-3)" "validated prognostic favorable (6.00e-4)" "validated prognostic favorable (9.76e-6)" "unprognostic (6.76e-2)" "unprognostic (3.17e-2)" "unprognostic (1.41e-1)" APOC4-APOC2 ENSG00000224916 "APOC4-APOC2 readthrough (NMD candidate)" 19 44942238-44949565 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 611 "liver: 1303.5" "Cell type enriched" "Detected in some" 114 "Hepatocytes: 168.0" "Cancer enriched" "Detected in some" 93 "Liver Hepatocellular Carcinoma (TCGA): 147.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA055877 Supported NA NA "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 70: DU4475 - Unknown function" "Cluster 93: Hepatocytes - Bile production & excretion" "HPA055877: " "potential prognostic favorable (1.64e-6)" "unprognostic (2.69e-1)" "unprognostic (2.36e-1)" "unprognostic (6.31e-2)" APOD Apo-D ENSG00000189058 "Apolipoprotein D" P05090 3 195568705-195584033 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 4727.6;choroid plexus: 4195.6" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 4996.4;Fibroblasts: 3441.8;Leydig cells: 1537.4;Melanocytes: 1181.0;Oligodendrocyte progenitor cells: 456.6;Peritubular myoid cells: 1097.2" "Cell type enriched" "Detected in all" 4 "fibroblast: 2810.5" "Cancer enriched" "Detected in all" 4 "Skin Cutaneous Melanoma (TCGA): 4040.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 14 "memory B-cell: 5.0" "Lineage enriched" "Detected in single" 14 "B-cells: 5.0" "Group enriched" "Detected in many" 4 "breast cancer: 117.8;prostate cancer: 92.2;skin cancer: 170.8" "Pancreas - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040520 Enhanced Approved "Plasma membrane" "Secreted to blood" Apolipoprotein NA NA 98900000000 6300000000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 30: White matter - Myelination" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 66 "Plasma membrane" "HPA040520: " "unprognostic (1.90e-2)" "unprognostic (3.81e-3)" "unprognostic (2.22e-2)" "unprognostic (3.64e-2)" "unprognostic (4.88e-2)" "unprognostic (3.86e-2)" "unprognostic (9.74e-2)" "unprognostic (2.15e-2)" "unprognostic (1.86e-2)" "unprognostic (1.03e-1)" "unprognostic (9.01e-2)" "unprognostic (9.17e-2)" "unprognostic (1.20e-1)" "unprognostic (7.56e-2)" "unprognostic (5.10e-3)" "unprognostic (4.71e-2)" "unprognostic (1.58e-1)" "unprognostic (7.03e-3)" "unprognostic (2.40e-1)" "unprognostic (8.21e-2)" "unprognostic (1.17e-1)" "unprognostic (2.97e-1)" "unprognostic (4.09e-3)" "unprognostic (1.94e-1)" "unprognostic (1.52e-3)" "unprognostic (8.90e-2)" "unprognostic (8.40e-2)" "unprognostic (1.13e-3)" "unprognostic (2.31e-1)" "unprognostic (1.16e-3)" "unprognostic (3.86e-2)" APOE AD2 ENSG00000130203 "Apolipoprotein E" P02649 19 44905791-44909393 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Cholesterol metabolism, Host-virus interaction, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" Heparin-binding "Alzheimer disease, Amyloidosis, Cancer-related genes, Disease variant, Hyperlipidemia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 3391.3;brain: 2714.9;liver: 6533.9" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 1311.9;Hepatocytes: 9962.2;Leydig cells: 2556.3;Macrophages: 1733.0;Melanocytes: 3427.4;Müller glia: 6740.1;Peritubular myoid cells: 4351.8" "Cell type enhanced" "Detected in all" "astrocyte: 1133.9;Bergmann glia: 1030.8;central nervous system macrophage: 624.3;vascular associated smooth muscle cell: 882.6" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 8197.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "liver cancer: 501.2;Rhabdoid: 348.5" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Macrophages, Skeletal muscle - Fibroblasts, Skin - Outer root sheath cells, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008363, HPA065539, HPA068768, CAB069921" Enhanced Approved Vesicles "Secreted to blood" Apolipoprotein NA NA 51800000000 17000000000 "Cluster 36: Brain & Liver - Signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 52 Vesicles "CAB008363: , CAB069921: , HPA065539: , HPA068768: " "unprognostic (1.18e-1)" "unprognostic (8.48e-2)" "unprognostic (1.94e-1)" "unprognostic (9.03e-2)" "unprognostic (9.43e-3)" "unprognostic (2.49e-1)" "unprognostic (1.08e-1)" "unprognostic (1.17e-1)" "unprognostic (2.02e-1)" "unprognostic (3.14e-1)" "unprognostic (1.74e-1)" "unprognostic (1.68e-2)" "unprognostic (1.36e-1)" "unprognostic (3.79e-3)" "potential prognostic favorable (7.01e-5)" "unprognostic (5.36e-2)" "unprognostic (4.16e-2)" "unprognostic (1.12e-1)" "unprognostic (1.85e-1)" "unprognostic (1.12e-1)" "unprognostic (4.62e-1)" "unprognostic (8.98e-2)" "unprognostic (3.53e-1)" "unprognostic (2.03e-1)" "unprognostic (1.40e-2)" "unprognostic (4.84e-2)" "unprognostic (2.03e-1)" "unprognostic (7.03e-2)" "unprognostic (2.97e-1)" "unprognostic (1.26e-3)" "unprognostic (1.12e-1)" APOF ENSG00000175336 "Apolipoprotein F" Q13790 12 56360568-56362857 "Plasma proteins, Predicted secreted proteins" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 343 "liver: 389.4" "Cell type enriched" "Detected in some" 30 "Hepatocytes: 346.5" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Liver Hepatocellular Carcinoma (TCGA): 42.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "prostate cancer: 1.0" "Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Testis - Early spermatids" "Not detected" "Not detected" "Secreted to blood" Apolipoprotein NA NA 18000000000 610000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 48: Non-specific - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 2 "unprognostic (1.32e-1)" "unprognostic (1.81e-1)" "unprognostic (4.29e-3)" "unprognostic (7.25e-3)" "unprognostic (5.37e-2)" "unprognostic (6.30e-2)" "unprognostic (7.73e-2)" "unprognostic (1.84e-2)" APOH "B2G1, BG" ENSG00000091583 "Apolipoprotein H" P02749 17 66212033-66256525 "Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Heparin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 564 "liver: 16781.5" "Cell type enriched" "Detected in some" 55 "Hepatocytes: 9195.7" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 211 "Liver Hepatocellular Carcinoma (TCGA): 4417.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 46 "liver cancer: 154.3" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Alveolar cells type 2, Pancreas - Alpha cells, Stomach - Parietal cells" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA001654, HPA003732, CAB022214" Enhanced Supported "Golgi apparatus" "Secreted to blood" Apolipoprotein NA NA 247000000000 58000000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 53: Neurons - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 93: Hepatocytes - Bile production & excretion" 9 "Golgi apparatus" "CAB022214: , HPA001654: , HPA003732: " "unprognostic (5.73e-2)" "unprognostic (1.48e-2)" "unprognostic (1.61e-3)" "unprognostic (2.24e-3)" "unprognostic (2.95e-2)" "potential prognostic favorable (5.45e-7)" "unprognostic (5.16e-3)" "unprognostic (8.40e-2)" "unprognostic (1.83e-1)" "unprognostic (4.58e-3)" "unprognostic (7.44e-3)" "unprognostic (1.84e-2)" "unprognostic (1.17e-1)" "unprognostic (3.27e-1)" "unprognostic (1.06e-2)" "unprognostic (6.63e-3)" "unprognostic (4.33e-2)" "unprognostic (1.06e-1)" APOL1 APOL ENSG00000100342 "Apolipoprotein L1" O14791 22 36253071-36267530 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 168.3" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 108.3;Endometrial glandular cells: 240.0;Endometrial luminal cells: 296.6;Endometrial secretory cells: 105.7;Foveolar cells: 326.6;Hepatocytes: 139.2;Prostatic hillock cells: 153.4;Urothelial cells: 211.1" "Group enriched" "Detected in some" 4 "endothelial cell: 30.4;fibroblast: 19.2;leukocyte: 8.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Kidney cancer: 244.0" "Heart muscle - Endothelial cells, Skeletal muscle - Endothelial cells" "HPA018885, CAB056156" Supported "Secreted to blood" Apolipoprotein NA NA 1640000000 4100000000 "Cluster 35: Neutrophils - Protein binding" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 15: Kidney cancer - Membrane components" "Cluster 68: Foveolar cells - Mucosal defense" 1 "CAB056156: , HPA018885: " "unprognostic (1.11e-1)" "unprognostic (6.31e-2)" "unprognostic (1.32e-1)" "unprognostic (9.64e-3)" "unprognostic (7.55e-2)" "unprognostic (8.91e-2)" "unprognostic (6.21e-2)" "unprognostic (5.54e-2)" "unprognostic (1.31e-2)" "unprognostic (3.63e-2)" "unprognostic (7.17e-3)" "unprognostic (6.84e-2)" "unprognostic (1.95e-1)" "unprognostic (4.61e-2)" "unprognostic (1.21e-3)" "potential prognostic unfavorable (3.50e-6)" "unprognostic (2.41e-1)" "unprognostic (3.86e-1)" "unprognostic (7.32e-2)" "unprognostic (2.25e-1)" "unprognostic (1.57e-2)" "potential prognostic unfavorable (6.47e-4)" "unprognostic (9.80e-3)" "unprognostic (1.25e-1)" "unprognostic (4.45e-2)" "unprognostic (8.11e-3)" "unprognostic (8.50e-2)" "unprognostic (9.03e-2)" "unprognostic (9.10e-2)" "unprognostic (2.02e-2)" "unprognostic (1.95e-1)" APOL2 APOL-II ENSG00000128335 "Apolipoprotein L2" Q9BQE5 22 36226209-36239954 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 74.9;Endometrial luminal cells: 119.7;Foveolar cells: 158.7;Hepatocytes: 76.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA001078, CAB026695" Supported NA NA 3200000 "Cluster 28: Neutrophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 24: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 27 "CAB026695: , HPA001078: " "unprognostic (1.25e-2)" "unprognostic (6.50e-2)" "unprognostic (1.09e-2)" "unprognostic (1.14e-1)" "unprognostic (9.19e-2)" "unprognostic (1.99e-1)" "unprognostic (2.40e-1)" "unprognostic (1.07e-1)" "unprognostic (1.37e-1)" "unprognostic (1.30e-2)" "unprognostic (3.37e-3)" "unprognostic (1.39e-1)" "unprognostic (9.25e-2)" "unprognostic (3.54e-2)" "unprognostic (2.82e-2)" "potential prognostic unfavorable (1.58e-4)" "unprognostic (3.48e-2)" "unprognostic (9.67e-2)" "unprognostic (3.56e-1)" "unprognostic (1.33e-1)" "unprognostic (9.53e-3)" "unprognostic (7.43e-3)" "unprognostic (1.69e-2)" "unprognostic (1.60e-1)" "unprognostic (1.78e-3)" "unprognostic (1.75e-2)" "unprognostic (4.76e-1)" "unprognostic (9.69e-2)" "unprognostic (3.25e-2)" "unprognostic (2.35e-2)" "unprognostic (2.39e-1)" APOL3 "APOLIII, CG12-1" ENSG00000128284 "Apolipoprotein L3" O95236 22 36140329-36166177 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "cDC: 42.2;Fibro-adipogenic progenitors: 49.3;Fibroblasts: 39.1;Kupffer cells: 42.0;Lymphatic endothelial cells: 56.7;T-cells: 36.6;Vascular endothelial cells: 85.0" "Group enriched" "Detected in some" 4 "endothelial cell: 72.8;leukocyte: 46.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Colon - Endothelial cells, Heart muscle - Endothelial cells, Skeletal muscle - Endothelial cells, Testis - Endothelial cells" "Intracellular and membrane" Apolipoprotein NA NA 4000000 "Cluster 33: Non-specific - ATP binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "potential prognostic favorable (1.38e-6)" "unprognostic (4.23e-3)" "unprognostic (3.89e-2)" "unprognostic (7.45e-3)" "unprognostic (2.59e-1)" "unprognostic (2.83e-1)" "unprognostic (5.10e-2)" "unprognostic (3.35e-2)" "unprognostic (5.37e-2)" "unprognostic (3.21e-3)" "potential prognostic favorable (4.00e-4)" "unprognostic (6.35e-3)" "unprognostic (3.17e-2)" "unprognostic (6.73e-2)" "potential prognostic favorable (1.87e-4)" "unprognostic (2.66e-1)" "unprognostic (1.39e-1)" "unprognostic (2.45e-1)" "unprognostic (4.06e-1)" "unprognostic (7.77e-2)" "unprognostic (1.79e-2)" "unprognostic (4.42e-2)" "unprognostic (3.62e-1)" "unprognostic (2.56e-1)" "unprognostic (2.03e-1)" "unprognostic (1.99e-1)" "unprognostic (7.21e-2)" "unprognostic (2.05e-1)" "unprognostic (9.73e-2)" "unprognostic (1.37e-1)" "unprognostic (1.59e-1)" APOL4 APOLIV ENSG00000100336 "Apolipoprotein L4" Q9BPW4 22 36189124-36204840 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 18.3;Endometrial glandular cells: 26.8;Endometrial luminal cells: 104.2;Fallopian tube ciliated cells: 48.2;Prostatic club cells: 18.6;Prostatic glandular cells: 29.5;Prostatic hillock cells: 19.1;Somatotrophs: 21.9;Urothelial cells: 16.7" "Cell type enhanced" "Detected in some" "endothelial cell: 2.4;fibroblast: 5.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Leukemia: 15.5;lymphoma: 4.5" "Minor Salivary Gland - Macrophages, Testis - Endothelial cells" "HPA049797, HPA055435" Uncertain Supported Vesicles "Secreted to blood" Apolipoprotein NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 13: Lung - Secretion" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 47: Leukemia - Hemostasis" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" Vesicles "HPA049797: , HPA055435: " "unprognostic (1.01e-2)" "unprognostic (6.58e-2)" "unprognostic (1.06e-1)" "unprognostic (4.83e-2)" "unprognostic (6.26e-2)" "unprognostic (6.68e-3)" "unprognostic (1.09e-1)" "unprognostic (1.30e-1)" "unprognostic (2.13e-1)" "unprognostic (4.97e-2)" "unprognostic (6.53e-3)" "unprognostic (8.73e-2)" "unprognostic (8.86e-2)" "unprognostic (3.53e-1)" "unprognostic (2.61e-1)" "unprognostic (9.49e-2)" "unprognostic (3.13e-1)" "unprognostic (2.24e-1)" "unprognostic (1.96e-2)" "unprognostic (2.85e-2)" "unprognostic (8.87e-3)" "unprognostic (4.91e-2)" "unprognostic (1.17e-1)" "unprognostic (4.50e-2)" "unprognostic (2.90e-1)" "unprognostic (6.63e-2)" "unprognostic (4.70e-2)" "unprognostic (1.71e-1)" "unprognostic (6.86e-2)" "unprognostic (4.27e-1)" APOL5 APOLV ENSG00000128313 "Apolipoprotein L5" Q9BWW9 22 35717872-35729483 "Plasma proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "skeletal muscle: 1.3;tongue: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Testis - Late spermatids" NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" "unprognostic (1.45e-1)" APOL6 "APOL-VI, APOLVI" ENSG00000221963 "Apolipoprotein L6" Q9BWW8 22 35648446-35668404 "Predicted membrane proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 43.5" "Cell type enhanced" "Detected in many" "Adipocytes: 141.8;Hepatocytes: 155.3;NK-cells: 120.7" "Cell type enhanced" "Detected in many" "leukocyte: 102.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB028574, HPA029165, HPA029167" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 7 "Nucleoplasm, Nuclear bodies" Cytosol "CAB028574: , HPA029165: , HPA029167: " "unprognostic (8.97e-2)" "unprognostic (2.05e-2)" "unprognostic (4.86e-2)" "unprognostic (4.51e-1)" "unprognostic (4.21e-2)" "unprognostic (2.12e-1)" "unprognostic (1.01e-1)" "unprognostic (2.79e-1)" "unprognostic (2.71e-1)" "unprognostic (9.98e-3)" "unprognostic (1.00e-2)" "unprognostic (3.58e-2)" "unprognostic (2.31e-1)" "unprognostic (7.15e-3)" "potential prognostic favorable (5.64e-5)" "unprognostic (2.44e-1)" "unprognostic (7.76e-2)" "unprognostic (2.28e-2)" "unprognostic (2.32e-1)" "unprognostic (4.25e-2)" "unprognostic (9.48e-3)" "unprognostic (1.42e-3)" "unprognostic (4.22e-2)" "unprognostic (3.20e-1)" "unprognostic (2.73e-3)" "unprognostic (2.37e-2)" "unprognostic (1.30e-1)" "unprognostic (1.00e-1)" "unprognostic (1.59e-1)" "unprognostic (3.36e-2)" "unprognostic (1.14e-1)" APOLD1 "DKFZP434F0318, FLJ25138" ENSG00000178878 "Apolipoprotein L domain containing 1" Q96LR9 12 12725917-12829975 "Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 116.6" "Cell type enhanced" "Detected in many" "Bergmann glia: 117.8;Choroid plexus epithelial cells: 137.7;Lymphatic endothelial cells: 254.4;Monocyte progenitors: 171.7;Müller glia: 240.5;Pericytes: 300.8;Retinal pigment epithelial cells: 238.7;Vascular endothelial cells: 308.5;Vascular smooth muscle cells: 367.7" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 166.9;endothelial cell: 270.2" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 88.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in many" 9 "skin cancer: 43.6" "Breast - Endothelial cells, Prostate - Endothelial cells" "Group enriched" "Detected in all" 4 "basal ganglia: 5.7;olfactory bulb: 20.1" "Low region specificity" "Detected in all" "HPA052462, HPA058882" Approved Supported "Nucleoplasm,Plasma membrane" No No "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 103: Non-specific - Basic cellular processes" "Nucleoplasm, Plasma membrane" "HPA052462: , HPA058882: " "unprognostic (5.17e-3)" "unprognostic (3.19e-1)" "unprognostic (1.54e-2)" "unprognostic (2.03e-2)" "unprognostic (1.09e-1)" "unprognostic (2.31e-1)" "unprognostic (1.51e-1)" "unprognostic (2.09e-1)" "unprognostic (2.57e-2)" "unprognostic (1.65e-1)" "validated prognostic favorable (2.12e-11)" "validated prognostic favorable (2.52e-5)" "unprognostic (4.42e-3)" "unprognostic (2.43e-2)" "unprognostic (7.68e-3)" "unprognostic (7.85e-2)" "unprognostic (2.55e-2)" "unprognostic (1.25e-1)" "unprognostic (2.61e-1)" "unprognostic (6.55e-3)" "unprognostic (2.69e-3)" "unprognostic (5.51e-2)" "unprognostic (2.25e-1)" "unprognostic (4.48e-2)" "unprognostic (2.04e-2)" "unprognostic (1.41e-3)" "unprognostic (3.28e-1)" "unprognostic (6.88e-3)" "unprognostic (1.23e-1)" "unprognostic (2.18e-2)" "unprognostic (1.28e-2)" APOM "Apo-M, G3a, NG20" ENSG00000204444 "Apolipoprotein M" O95445 6 31652416-31658210 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 448.8" "Cell type enriched" "Detected in many" 7 "Hepatocytes: 693.8" "Low cell type specificity" "Detected in some" "Cancer enriched" "Detected in some" 9 "Liver Hepatocellular Carcinoma (TCGA): 83.1" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "basophil: 3.0" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "liver cancer: 6.4" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB034086, HPA051006" Approved Approved "Golgi apparatus" "Secreted to blood" Apolipoprotein NA NA 7400000000 2400000000 "Cluster 32: Basophils - Transcription" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 25: Non-specific - Transcription" "Cluster 18: Liver cancer - Metabolism" "Cluster 93: Hepatocytes - Bile production & excretion" 14 "Golgi apparatus" "CAB034086: , HPA051006: " "unprognostic (1.31e-1)" "unprognostic (1.78e-1)" "unprognostic (1.40e-1)" "validated prognostic favorable (2.61e-6)" "validated prognostic favorable (1.67e-6)" "unprognostic (4.65e-2)" "unprognostic (4.33e-1)" "unprognostic (1.71e-3)" "unprognostic (1.91e-1)" "unprognostic (1.35e-1)" "unprognostic (3.81e-1)" "unprognostic (1.09e-1)" APOO "FAM121B, MGC4825, Mic23, MIC26, MICOS26, My025" ENSG00000184831 "Apolipoprotein O" Q9BUR5 X 23833353-23907938 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 102.5" "Cell type enhanced" "Detected in all" "Papillary tip epithelial cells: 273.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003187 Supported Supported Mitochondria,Cytosol "Secreted to blood" Apolipoprotein NA NA 2210000000 "Cluster 13: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cellular respiration" "Cluster 23: Choroid plexus - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 15: Non-specific - Protein processing" 8 Mitochondria Cytosol "HPA003187: " "unprognostic (7.11e-2)" "potential prognostic unfavorable (5.70e-4)" "unprognostic (1.37e-1)" "potential prognostic favorable (8.54e-4)" "unprognostic (2.66e-2)" "unprognostic (3.31e-2)" "unprognostic (4.16e-2)" "unprognostic (2.42e-2)" "unprognostic (5.34e-2)" "unprognostic (1.11e-3)" "unprognostic (1.08e-1)" "unprognostic (5.38e-3)" "unprognostic (1.45e-2)" "unprognostic (2.41e-2)" "unprognostic (4.19e-2)" "unprognostic (6.53e-3)" "unprognostic (1.21e-1)" "unprognostic (6.85e-2)" "unprognostic (1.31e-1)" "unprognostic (1.79e-2)" "unprognostic (2.64e-1)" "unprognostic (1.33e-1)" "unprognostic (2.26e-1)" "unprognostic (2.17e-1)" "unprognostic (2.36e-1)" "unprognostic (3.14e-1)" "unprognostic (3.03e-1)" "unprognostic (1.42e-1)" "unprognostic (4.53e-2)" "unprognostic (2.52e-1)" "unprognostic (2.07e-1)" APOOL "AAIR8193, CXorf33, FAM121A, Mic27, MICOS27, UNQ8193" ENSG00000155008 "Apolipoprotein O like" Q6UXV4 X 85003877-85093315 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000612, HPA076210" Approved Enhanced Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 76: Non-specific - Metabolism" "Cluster 45: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 9 Mitochondria "HPA000612: , HPA076210: " "unprognostic (4.34e-2)" "potential prognostic unfavorable (6.52e-5)" "unprognostic (6.96e-2)" "unprognostic (4.95e-2)" "unprognostic (1.66e-1)" "unprognostic (1.10e-1)" "unprognostic (4.57e-2)" "unprognostic (1.31e-1)" "unprognostic (1.76e-1)" "unprognostic (6.14e-3)" "potential prognostic favorable (2.54e-9)" "unprognostic (3.68e-3)" "unprognostic (1.44e-2)" "unprognostic (2.36e-1)" "unprognostic (9.27e-2)" "unprognostic (1.52e-1)" "unprognostic (8.06e-2)" "unprognostic (1.68e-1)" "unprognostic (7.82e-2)" "unprognostic (5.29e-2)" "unprognostic (1.48e-2)" "unprognostic (3.86e-1)" "unprognostic (7.76e-2)" "unprognostic (1.27e-1)" "unprognostic (2.45e-1)" "unprognostic (2.16e-1)" "unprognostic (9.45e-2)" "unprognostic (5.49e-2)" "unprognostic (3.99e-2)" "unprognostic (3.25e-2)" "unprognostic (1.56e-1)" APP "AD1, alpha-sAPP" ENSG00000142192 "Amyloid beta precursor protein" P05067 21 25880535-26171128 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Apoptosis, Cell adhesion, Endocytosis, Notch signaling pathway" "Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Alzheimer disease, Amyloidosis, Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Lymphatic endothelial cells: 1230.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "plasmacytoid DC: 36.4" "Lineage enriched" "Detected in many" 5 "dendritic cells: 36.4" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000157, HPA001462" Enhanced Supported "Golgi apparatus,Vesicles" "Secreted to blood" "Cell adhesion" NA NA 86000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 36: Brain & Liver - Signaling" "Cluster 27: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 499 "Golgi apparatus" Vesicles "CAB000157: , HPA001462: " "unprognostic (5.14e-2)" "unprognostic (3.42e-1)" "unprognostic (2.22e-1)" "unprognostic (3.69e-3)" "unprognostic (1.00e-1)" "unprognostic (1.14e-1)" "unprognostic (2.60e-1)" "unprognostic (1.28e-1)" "unprognostic (4.67e-3)" "unprognostic (1.03e-1)" "validated prognostic favorable (8.44e-9)" "validated prognostic favorable (1.85e-5)" "unprognostic (1.82e-1)" "unprognostic (1.43e-1)" "unprognostic (9.93e-2)" "unprognostic (8.97e-3)" "unprognostic (3.91e-2)" "unprognostic (6.82e-3)" "unprognostic (9.35e-3)" "unprognostic (5.29e-2)" "unprognostic (6.25e-2)" "unprognostic (1.31e-2)" "unprognostic (4.34e-2)" "unprognostic (1.96e-2)" "unprognostic (2.28e-1)" "unprognostic (1.40e-1)" "unprognostic (2.43e-1)" "unprognostic (3.59e-1)" "unprognostic (4.49e-1)" "unprognostic (1.10e-1)" "unprognostic (2.46e-2)" APPBP2 "Hs.84084, KIAA0228, PAT1" ENSG00000062725 "Amyloid beta precursor protein binding protein 2" Q92624 17 60443158-60526242 "Cancer-related genes, Predicted intracellular proteins" "Protein transport, Transport, Ubl conjugation pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 503.5;Podocytes: 326.8;Sertoli cells: 327.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066852, HPA078370" Supported Supported Nucleoplasm NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 7: Non-specific - Transcription" 109 Nucleoplasm "HPA066852: , HPA078370: " "potential prognostic favorable (5.80e-4)" "unprognostic (1.20e-1)" "unprognostic (9.64e-2)" "unprognostic (4.04e-2)" "unprognostic (3.48e-2)" "unprognostic (1.30e-2)" "unprognostic (2.28e-1)" "unprognostic (7.81e-3)" "unprognostic (2.41e-1)" "potential prognostic unfavorable (1.30e-4)" "potential prognostic favorable (3.67e-5)" "unprognostic (3.84e-2)" "unprognostic (7.52e-2)" "potential prognostic unfavorable (3.92e-4)" "unprognostic (7.53e-3)" "unprognostic (1.33e-1)" "unprognostic (4.25e-1)" "unprognostic (2.32e-1)" "unprognostic (3.07e-2)" "unprognostic (1.84e-1)" "unprognostic (1.72e-2)" "unprognostic (1.21e-2)" "unprognostic (4.46e-1)" "unprognostic (2.38e-2)" "unprognostic (2.99e-2)" "unprognostic (1.26e-1)" "unprognostic (1.11e-1)" "unprognostic (9.62e-2)" "unprognostic (1.02e-1)" "unprognostic (7.47e-2)" "unprognostic (2.35e-1)" APPL1 APPL ENSG00000157500 "Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1" Q9UKG1 3 57227726-57278105 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "naive B-cell: 28.4" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011138 Approved Supported "Vesicles,Plasma membrane,Actin filaments,Cytosol" NA No 11000 "Cluster 34: B-cells - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 82: Dendritic cells - Antigen presentation" 108 "Vesicles, Plasma membrane" "Actin filaments, Cytosol" "HPA011138: " "unprognostic (6.26e-2)" "unprognostic (1.54e-1)" "unprognostic (2.65e-2)" "unprognostic (3.12e-2)" "unprognostic (1.57e-1)" "unprognostic (1.34e-1)" "unprognostic (5.21e-2)" "unprognostic (5.45e-2)" "unprognostic (6.61e-3)" "unprognostic (6.59e-3)" "potential prognostic favorable (4.28e-7)" "unprognostic (5.07e-3)" "unprognostic (3.45e-1)" "unprognostic (2.58e-3)" "unprognostic (7.58e-3)" "unprognostic (6.57e-2)" "unprognostic (2.33e-2)" "unprognostic (1.14e-1)" "unprognostic (7.84e-2)" "unprognostic (1.54e-1)" "unprognostic (1.06e-2)" "unprognostic (7.31e-3)" "unprognostic (1.49e-1)" "unprognostic (1.07e-2)" "unprognostic (1.46e-2)" "unprognostic (2.87e-1)" "unprognostic (1.65e-1)" "unprognostic (1.17e-1)" "unprognostic (2.89e-1)" "unprognostic (1.32e-3)" "unprognostic (6.53e-2)" APPL2 "DIP13B, FLJ10659" ENSG00000136044 "Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2" Q8NEU8 12 105173297-105236203 "Disease related genes, Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglia: 417.1;Sertoli cells: 321.5" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 531.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 21.2" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039688, HPA043925, HPA079223" Approved Approved Vesicles,Cytosol NA NA 45000 "Cluster 35: Neutrophils - Protein binding" "Cluster 77: Intestine - Digestion" "Cluster 25: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 38 Vesicles Cytosol "HPA039688: , HPA043925: , HPA079223: " "unprognostic (9.18e-2)" "unprognostic (1.42e-1)" "unprognostic (1.90e-2)" "unprognostic (8.49e-2)" "unprognostic (6.00e-2)" "unprognostic (1.27e-1)" "unprognostic (2.07e-1)" "unprognostic (1.47e-1)" "unprognostic (1.10e-2)" "potential prognostic unfavorable (7.39e-5)" "potential prognostic favorable (3.51e-4)" "unprognostic (5.83e-2)" "unprognostic (2.56e-2)" "unprognostic (7.46e-3)" "unprognostic (2.73e-2)" "unprognostic (1.17e-1)" "unprognostic (7.67e-2)" "unprognostic (3.62e-2)" "potential prognostic favorable (2.28e-4)" "unprognostic (1.82e-2)" "unprognostic (7.17e-2)" "unprognostic (6.79e-2)" "unprognostic (1.25e-1)" "unprognostic (9.37e-2)" "potential prognostic favorable (5.67e-4)" "unprognostic (4.23e-1)" "unprognostic (1.55e-1)" "unprognostic (1.46e-1)" "unprognostic (1.69e-1)" "unprognostic (1.45e-1)" "unprognostic (1.14e-1)" APRT ENSG00000198931 "Adenine phosphoribosyltransferase" P07741 16 88809339-88811937 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Purine salvage" "Glycosyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal basal cells: 848.3;Esophageal suprabasal cells: 1171.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026681 Approved Approved Nucleoplasm,Cytosol NA NA 1200000 "Cluster 13: Non-specific - Mitochondria" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 97: Non-specific - Cellular respiration" 6 "Nucleoplasm, Cytosol" "HPA026681: " "unprognostic (9.60e-2)" "unprognostic (3.06e-2)" "unprognostic (6.73e-2)" "unprognostic (3.13e-1)" "unprognostic (1.03e-2)" "unprognostic (1.08e-1)" "unprognostic (3.25e-1)" "unprognostic (4.23e-2)" "unprognostic (1.35e-2)" "unprognostic (6.07e-2)" "unprognostic (3.91e-3)" "unprognostic (1.62e-2)" "potential prognostic favorable (9.42e-4)" "validated prognostic unfavorable (6.93e-4)" "validated prognostic unfavorable (1.54e-4)" "unprognostic (2.82e-2)" "unprognostic (7.24e-3)" "unprognostic (9.80e-2)" "unprognostic (2.32e-1)" "unprognostic (3.04e-1)" "unprognostic (4.91e-1)" "unprognostic (9.14e-3)" "unprognostic (1.47e-1)" "unprognostic (4.82e-2)" "unprognostic (9.87e-2)" "unprognostic (1.83e-1)" "unprognostic (3.94e-1)" "unprognostic (2.49e-2)" "unprognostic (1.62e-1)" "unprognostic (2.46e-1)" "unprognostic (1.44e-2)" APTX "AOA, AOA1, AXA1, EAOH, EOAHA, FLJ20157" ENSG00000137074 Aprataxin Q7Z2E3 9 32886601-33025130 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Hydrolase" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064930 Supported Supported Nucleoplasm,Nucleoli No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 76: Non-specific - Metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 16 "Nucleoplasm, Nucleoli" "HPA064930: " "unprognostic (4.93e-2)" "unprognostic (1.88e-1)" "potential prognostic unfavorable (4.78e-4)" "unprognostic (1.60e-1)" "unprognostic (2.18e-1)" "unprognostic (3.10e-1)" "unprognostic (2.38e-1)" "unprognostic (9.85e-3)" "unprognostic (3.01e-2)" "unprognostic (5.43e-2)" "validated prognostic favorable (1.39e-7)" "validated prognostic favorable (9.97e-4)" "unprognostic (2.60e-3)" "unprognostic (5.81e-2)" "unprognostic (9.46e-2)" "unprognostic (1.35e-1)" "unprognostic (3.57e-2)" "unprognostic (2.10e-2)" "unprognostic (9.86e-3)" "unprognostic (3.74e-2)" "unprognostic (2.23e-1)" "unprognostic (9.74e-3)" "unprognostic (1.32e-2)" "unprognostic (3.19e-1)" "unprognostic (5.56e-2)" "unprognostic (2.92e-1)" "unprognostic (2.85e-2)" "unprognostic (9.03e-2)" "unprognostic (2.13e-1)" "unprognostic (1.50e-1)" "unprognostic (8.45e-3)" AQP1 "CHIP28, CO" ENSG00000240583 "Aquaporin 1 (Colton blood group)" P29972 7 30911853-30925517 "Blood group antigen proteins, Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 765.7;choroid plexus: 764.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 466.6;Alveolar cells type 2: 430.8;Cholangiocytes: 372.7;Mesothelial cells: 247.4;Pancreatic duct cells: 346.2;Smooth muscle cells: 141.5;Transitional alveolar cells: 126.2;Vascular endothelial cells: 740.7" "Group enriched" "Detected in many" 6 "astrocyte: 220.1;choroid plexus epithelial cell: 82.5" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 577.9;Kidney Renal Papillary Cell Carcinoma (TCGA): 736.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 50.3" "Breast - Endothelial cells, Minor Salivary Gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Testis - Endothelial cells" "Region enriched" "Detected in many" 5 "olfactory bulb: 46.6" "Region enriched" "Detected in many" 4 "spinal cord: 29.0" "CAB001707, HPA019206" Enhanced Supported "Plasma membrane" NA NA 1600000 "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 22: Non-specific - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 109 "Plasma membrane" "CAB001707: , HPA019206: " "unprognostic (2.23e-1)" "unprognostic (1.62e-1)" "unprognostic (1.17e-2)" "unprognostic (1.98e-1)" "unprognostic (3.33e-3)" "unprognostic (8.98e-2)" "unprognostic (1.40e-1)" "unprognostic (2.27e-2)" "potential prognostic favorable (1.63e-4)" "unprognostic (8.39e-2)" "validated prognostic favorable (6.00e-14)" "validated prognostic favorable (1.30e-6)" "potential prognostic favorable (3.21e-5)" "unprognostic (1.78e-2)" "unprognostic (2.19e-3)" "unprognostic (2.40e-2)" "unprognostic (9.25e-2)" "unprognostic (4.21e-3)" "unprognostic (2.90e-1)" "potential prognostic unfavorable (2.53e-4)" "unprognostic (1.47e-1)" "unprognostic (2.67e-1)" "unprognostic (3.40e-2)" "unprognostic (1.56e-2)" "unprognostic (2.01e-2)" "unprognostic (2.32e-2)" "unprognostic (1.53e-1)" "unprognostic (1.21e-1)" "unprognostic (3.42e-1)" "unprognostic (7.18e-2)" "unprognostic (2.61e-1)" AQP10 ENSG00000143595 "Aquaporin 10" Q96PS8 1 154321090-154325325 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "intestine: 64.5" "Cell type enriched" "Detected in some" 30 "Platelets: 565.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 1.5;Neuroblastoma: 1.1" "Testis - Sertoli cells" "Not detected" "Not detected" "HPA062621, HPA065947" Enhanced Supported "Vesicles,Plasma membrane" NA NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 47: Leukemia - Hemostasis" "Cluster 47: Platelets - Hemostasis" 17 "Plasma membrane" Vesicles "HPA062621: , HPA065947: " AQP11 AQPX1 ENSG00000178301 "Aquaporin 11" Q8NBQ7 11 77589391-77610356 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 14.1;intestine: 27.0;liver: 15.1" "Cell type enhanced" "Detected in many" "Enterocytes: 61.7;Hepatocytes: 50.0;Late primary spermatocytes: 86.0;Late spermatids: 104.7;Müller glia: 48.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077460 Supported "Vesicles,Plasma membrane" NA NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 1: Neurons - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "Plasma membrane" Vesicles "HPA077460: " "unprognostic (3.08e-1)" "unprognostic (2.52e-1)" "unprognostic (1.54e-2)" "unprognostic (7.07e-2)" "unprognostic (1.12e-1)" "unprognostic (1.10e-1)" "unprognostic (4.81e-2)" "unprognostic (4.41e-2)" "unprognostic (7.56e-2)" "unprognostic (2.07e-1)" "unprognostic (2.22e-1)" "unprognostic (2.36e-1)" "unprognostic (1.19e-1)" "unprognostic (2.39e-1)" "potential prognostic favorable (2.37e-4)" "unprognostic (6.81e-3)" "unprognostic (1.37e-1)" "unprognostic (1.83e-1)" "unprognostic (7.40e-3)" "unprognostic (1.58e-1)" "unprognostic (6.31e-2)" "unprognostic (6.58e-2)" "unprognostic (9.33e-2)" "unprognostic (1.63e-1)" "unprognostic (2.23e-1)" "unprognostic (3.04e-1)" AQP12A AQP12 ENSG00000184945 "Aquaporin 12A" Q8IXF9 2 240691866-240698483 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 328 "pancreas: 99.2" "Cell type enhanced" "Detected in some" "Colonocytes: 1.4;Enterocytes: 1.6" "Cancer enriched" "Detected in single" 4 "Pancreatic Adenocarcinoma (TCGA): 1.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA042216 Supported NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" "HPA042216: " "unprognostic (2.01e-1)" "unprognostic (4.34e-2)" AQP12B INSSA3 ENSG00000185176 "Aquaporin 12B" A6NM10 2 240676418-240682906 "Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 336 "pancreas: 201.3" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "Pancreatic Adenocarcinoma (TCGA): 2.8" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enteroendocrine cells" HPA042216 Supported NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 24: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" "HPA042216: " "unprognostic (1.13e-1)" "unprognostic (1.66e-1)" AQP2 ENSG00000167580 "Aquaporin 2" P41181 12 49950737-49958878 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Diabetes insipidus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 113 "kidney: 450.4;seminal vesicle: 200.5" "Cell type enriched" "Detected in some" 5 "Renal collecting duct principal cells: 1012.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney Renal Papillary Cell Carcinoma (TCGA): 7.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 1.1;Gastric cancer: 1.2" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells (progenitors), Minor Salivary Gland - Minor salivary glandular cells, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA046834 Enhanced NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 36 "HPA046834: " "unprognostic (1.05e-1)" "unprognostic (8.72e-2)" "unprognostic (1.51e-1)" "unprognostic (4.40e-2)" "unprognostic (1.48e-2)" "unprognostic (1.60e-1)" AQP3 GIL ENSG00000165272 "Aquaporin 3 (Gill blood group)" Q92482 9 33441156-33447596 "Blood group antigen proteins, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" Transport "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 1457.5;skin 1: 554.4;urinary bladder: 642.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 1612.8;Esophageal apical cells: 4827.1;Esophageal basal cells: 3864.2;Esophageal suprabasal cells: 7328.2;Ocular epithelial cells: 1729.1;Prostatic hillock cells: 1115.0;Respiratory basal cells: 1096.3;Respiratory secretory cells: 1045.1;Suprabasal keratinocytes: 2386.4;Urothelial cells: 1101.8" "Group enriched" "Detected in some" 4 "hippocampal dentate gyrus: 6.8;leukocyte: 21.1;lower rhombic lip: 16.7" "Group enriched" "Detected in all" 5 "Bladder Urothelial Carcinoma (TCGA): 524.5;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 859.9;Head and Neck Squamous Cell Carcinoma (TCGA): 631.6;Lung Adenocarcinoma (TCGA): 432.7;Lung Squamous Cell Carcinoma (TCGA): 216.3" "Region enhanced" "Detected in all" "pons: 47.2" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 182.0;T-reg: 205.9" "Lineage enriched" "Detected in many" 18 "T-cells: 205.9" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 403.6" "Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary gland basal cells, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA014924 Enhanced Supported "Plasma membrane" NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 23 "Plasma membrane" "HPA014924: " "unprognostic (1.80e-3)" "unprognostic (7.60e-2)" "unprognostic (5.02e-2)" "unprognostic (1.02e-3)" "unprognostic (4.94e-2)" "unprognostic (3.32e-2)" "unprognostic (5.08e-3)" "unprognostic (1.60e-1)" "unprognostic (1.49e-2)" "unprognostic (1.88e-1)" "unprognostic (4.49e-3)" "unprognostic (3.47e-3)" "unprognostic (1.28e-1)" "unprognostic (8.21e-2)" "unprognostic (2.75e-1)" "unprognostic (4.24e-3)" "unprognostic (2.18e-2)" "unprognostic (7.24e-3)" "unprognostic (2.74e-1)" "unprognostic (1.42e-1)" "unprognostic (3.46e-2)" "unprognostic (1.60e-2)" "unprognostic (1.59e-1)" "unprognostic (1.23e-1)" "unprognostic (7.32e-2)" "unprognostic (2.92e-3)" "unprognostic (2.70e-1)" "unprognostic (2.77e-2)" "unprognostic (2.59e-1)" "unprognostic (4.26e-2)" "unprognostic (7.73e-2)" AQP4 "AQP-4, hAQP4, MIWC" ENSG00000171885 "Aquaporin 4" P55087 18 26852043-26865771 "Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 354.4;lung: 108.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 568.4;Alveolar cells type 2: 318.0;Astrocytes: 742.9;Bergmann glia: 125.9;Ependymal cells: 261.0;Müller glia: 226.5;Parietal cells: 123.8;Transitional alveolar cells: 392.4" "Cell type enhanced" "Detected in many" "astrocyte: 951.4;Bergmann glia: 217.4;ependymal cell: 376.8" "Cancer enriched" "Detected in some" 16 "Glioblastoma Multiforme (TCGA): 397.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Brain cancer: 2.5;Rhabdoid: 1.7" "Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005079, HPA014784, CAB058689" Enhanced Supported Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 39: Astrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 28: Astrocytes - Homeostasis & neuron support" 4 "Plasma membrane" "Cell Junctions" "CAB005079: , CAB058689: , HPA014784: " "unprognostic (3.25e-1)" "unprognostic (6.75e-2)" "unprognostic (1.84e-1)" "potential prognostic favorable (3.94e-7)" "unprognostic (1.34e-3)" "unprognostic (7.21e-3)" "unprognostic (8.03e-2)" "unprognostic (4.87e-3)" "unprognostic (3.68e-1)" "unprognostic (9.85e-2)" AQP5 ENSG00000161798 "Aquaporin 5" P55064 12 49961872-49965682 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 586.3;testis: 211.1" "Cell type enriched" "Detected in many" 4 "Late spermatids: 6777.5" "Cell type enhanced" "Detected in some" "Bergmann glia: 3.0;oligodendrocyte precursor cell: 4.7" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 125.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 57.1;Gastric cancer: 24.2" "Breast - Breast glandular cells (progenitors), Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Skin - Eccrine sweat gland cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA065008 Enhanced Approved "Plasma membrane" NA NA "Cluster 21: Testis - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 7 "Plasma membrane" "HPA065008: " "unprognostic (2.20e-3)" "unprognostic (5.07e-3)" "potential prognostic favorable (1.05e-4)" "unprognostic (1.44e-1)" "unprognostic (2.37e-2)" "validated prognostic unfavorable (9.90e-4)" "validated prognostic unfavorable (1.22e-5)" "potential prognostic favorable (7.60e-5)" "unprognostic (7.38e-3)" "unprognostic (3.00e-1)" "unprognostic (1.98e-1)" "unprognostic (3.11e-1)" "unprognostic (1.95e-3)" "unprognostic (4.68e-2)" "unprognostic (3.20e-3)" "unprognostic (6.07e-2)" "unprognostic (2.10e-2)" "unprognostic (9.50e-2)" "unprognostic (3.19e-1)" "unprognostic (4.57e-1)" "unprognostic (2.56e-3)" "unprognostic (7.38e-3)" AQP6 AQP2L ENSG00000086159 "Aquaporin 6" Q13520 12 49967194-49977139 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "kidney: 47.5" "Group enriched" "Detected in some" 15 "Epididymal clear cells: 79.6;Renal collecting duct intercalated cells: 274.8" "Cell type enriched" "Detected in some" 4 "astrocyte: 17.8" "Cancer enriched" "Detected in many" 11 "Kidney Chromophobe (TCGA): 182.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Breast glandular cells (progenitors), Colon - Enteric glia cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Skin - Eccrine sweat gland cells" "Region enriched" "Detected in some" 7 "cerebellum: 21.0" "Not detected" "Not detected" HPA015278 Enhanced NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 264 "HPA015278: " "unprognostic (6.01e-3)" "unprognostic (8.71e-2)" "unprognostic (8.61e-2)" "unprognostic (2.03e-1)" "unprognostic (2.80e-1)" "unprognostic (3.80e-3)" "unprognostic (1.20e-1)" "unprognostic (2.30e-1)" "unprognostic (1.04e-2)" "unprognostic (1.47e-1)" "unprognostic (2.15e-1)" "unprognostic (6.32e-2)" AQP7 "AQP7L, AQP9, AQPap" ENSG00000165269 "Aquaporin 7" O14520 9 33383179-33402682 "Essential proteins, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 200.1;breast: 87.3;heart muscle: 90.1" "Cell type enhanced" "Detected in many" "Adipocytes: 764.6;Cardiomyocytes: 449.9;Early spermatids: 141.0;Enterocytes: 191.1;Late primary spermatocytes: 92.5;Myonuclei: 175.3" "Cell type enhanced" "Detected in some" "lower rhombic lip: 19.0;upper rhombic lip: 7.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Minor Salivary Gland - Adipocytes (Minor salivary gland), Testis - Early spermatids, Testis - Late spermatids" HPA048106 Uncertain "Nucleoplasm,Nuclear speckles,Vesicles" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 49: Hindbrain - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 89: Adipocytes - Lipid metabolism" 1 Vesicles "Nucleoplasm, Nuclear speckles" "HPA048106: " "unprognostic (1.79e-1)" "unprognostic (3.80e-2)" "unprognostic (1.41e-2)" "unprognostic (1.27e-2)" "unprognostic (9.01e-3)" "unprognostic (1.36e-2)" "unprognostic (1.78e-2)" "validated prognostic favorable (1.36e-4)" "validated prognostic favorable (2.07e-5)" "unprognostic (3.87e-2)" "unprognostic (1.54e-1)" "unprognostic (1.70e-1)" "unprognostic (4.58e-2)" "unprognostic (1.82e-3)" "potential prognostic favorable (5.57e-6)" "unprognostic (8.17e-2)" "unprognostic (1.50e-1)" "unprognostic (1.50e-1)" "unprognostic (3.70e-2)" "unprognostic (1.66e-1)" AQP7B ENSG00000259916 "Aquaporin 7B" 2 94587101-94612744 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 12 "adipose tissue: 29.7" "Cell type enriched" "Detected in some" 6 "Adipocytes: 205.1" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Gallbladder cancer: 1.2" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Minor Salivary Gland - Adipocytes (Minor salivary gland), Skin - Adipocytes (Skin)" HPA048106 Uncertain "Nucleoplasm,Nuclear speckles,Vesicles" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 89: Adipocytes - Lipid metabolism" Vesicles "Nucleoplasm, Nuclear speckles" "HPA048106: " AQP8 ENSG00000103375 "Aquaporin 8" O94778 16 25215731-25228932 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 460 "intestine: 309.2;pancreas: 1207.4" "Cell type enriched" "Detected in some" 8 "Colonocytes: 1686.5" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in some" "Colon Adenocarcinoma (TCGA): 11.6;Pancreatic Adenocarcinoma (TCGA): 20.7;Rectum Adenocarcinoma (TCGA): 10.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enterocytes, Pancreas - Exocrine glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA046259 Enhanced NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 15: Non-specific - Transcription" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 11 "HPA046259: " "unprognostic (4.13e-2)" "unprognostic (7.55e-2)" "unprognostic (1.01e-1)" "potential prognostic favorable (2.60e-4)" "unprognostic (1.27e-2)" "unprognostic (1.87e-2)" "unprognostic (1.38e-2)" "unprognostic (1.37e-1)" AQP9 "HsT17287, SSC1" ENSG00000103569 "Aquaporin 9" O43315 15 58138169-58185911 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "liver: 657.2" "Cell type enriched" "Detected in many" 9 "Neutrophils: 8994.7" "Cell type enriched" "Detected in many" 6 "hippocampal dentate gyrus: 78.6" "Cancer enriched" "Detected in many" 29 "Liver Hepatocellular Carcinoma (TCGA): 188.2" "Region enhanced" "Detected in many" "cerebral cortex: 28.1" "Immune cell enriched" "Detected in many" 20 "neutrophil: 1165.9" "Lineage enriched" "Detected in many" 20 "granulocytes: 1165.9" "Cancer enriched" "Detected in single" 9 "lymphoma: 9.0" "Colon - Neutrophils, Heart muscle - Neutrophils, Liver - Hepatocytes, Lung - Neutrophils_2, Pituitary gland - Neutrophils, Skeletal muscle - Neutrophils, Skin - Keratinocyte (granular), Spleen - Neutrophils_2, Stomach - Neutrophils, Thyroid gland - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA074762, CAB075684" Enhanced Approved "Mid piece" NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 12: Non-specific - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 19 "Mid piece" "CAB075684: , HPA074762: " "unprognostic (1.99e-1)" "unprognostic (1.83e-1)" "unprognostic (1.96e-1)" "unprognostic (1.35e-1)" "unprognostic (1.49e-1)" "unprognostic (9.30e-2)" "potential prognostic unfavorable (9.53e-4)" "unprognostic (6.72e-2)" "unprognostic (3.29e-2)" "unprognostic (4.09e-1)" "potential prognostic unfavorable (6.00e-5)" "unprognostic (2.84e-3)" "unprognostic (6.67e-3)" "unprognostic (1.02e-3)" "unprognostic (8.59e-3)" "unprognostic (1.11e-1)" "unprognostic (2.47e-2)" "unprognostic (2.73e-3)" "unprognostic (3.44e-1)" "unprognostic (3.90e-2)" "unprognostic (8.40e-2)" "unprognostic (4.13e-3)" "unprognostic (3.39e-2)" "potential prognostic unfavorable (6.45e-4)" "unprognostic (2.49e-1)" "unprognostic (5.53e-2)" "unprognostic (1.34e-1)" "unprognostic (8.59e-3)" "unprognostic (2.15e-1)" AQR "fSAP164, IBP160, KIAA0560" ENSG00000021776 "Aquarius intron-binding spliceosomal factor" O60306 15 34851782-34969742 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040624, HPA055647" Enhanced Nucleoplasm No No "Cluster 22: Eosinophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" 85 Nucleoplasm "HPA040624: , HPA055647: " "unprognostic (7.05e-2)" "unprognostic (6.74e-3)" "unprognostic (1.76e-1)" "unprognostic (2.19e-1)" "unprognostic (7.75e-2)" "unprognostic (5.35e-2)" "unprognostic (2.93e-2)" "unprognostic (1.45e-2)" "unprognostic (1.37e-1)" "unprognostic (2.52e-1)" "validated prognostic favorable (2.22e-7)" "validated prognostic favorable (1.82e-5)" "unprognostic (1.84e-2)" "unprognostic (2.78e-1)" "unprognostic (1.94e-1)" "unprognostic (1.09e-1)" "unprognostic (4.78e-1)" "unprognostic (3.22e-2)" "unprognostic (4.32e-2)" "unprognostic (4.16e-2)" "unprognostic (7.56e-2)" "unprognostic (2.52e-1)" "unprognostic (6.74e-3)" "unprognostic (7.31e-2)" "unprognostic (5.39e-2)" "unprognostic (3.67e-1)" "unprognostic (2.40e-1)" "unprognostic (3.44e-2)" "unprognostic (1.81e-1)" "unprognostic (6.68e-2)" "unprognostic (6.90e-2)" AR "AIS, DHTR, HUMARA, NR3C4, SBMA, SMAX1" ENSG00000169083 "Androgen receptor" P10275 X 67544021-67730619 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Cancer-related genes, Disease variant, FDA approved drug targets, Neurodegeneration, Pseudohermaphroditism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 35.8" "Cell type enhanced" "Detected in many" "Adipocytes: 241.0;Breast hormone-responsive cells: 234.0;Epididymal efferent duct absorptive cells: 211.6;Epididymal principal cells: 174.3;Fallopian secretory cells: 193.3;Hepatocytes: 420.6;Pituitary stem cells: 226.9;Prostatic glandular cells: 918.9;Sertoli cells: 284.0" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 24.7;Prostate Adenocarcinoma (TCGA): 21.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 11 "prostate cancer: 91.0" "Adipose subcutaneous - Adipocytes (Subcutaneous), Kidney - Fibroblasts, Liver - Hepatocytes, Liver - Hepatocytes, Pancreas - Fibroblasts, Pituitary gland - Undifferentiated cells (Pituitary gland), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB000001, HPA004733, CAB065764" Enhanced Supported Cytosol NA NA "Cluster 16: Liver & Kidney - Metabolism" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 60: Prostate cancer - Unknown function" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 330 Cytosol "CAB000001: , CAB065764: , HPA004733: " "unprognostic (1.28e-2)" "unprognostic (3.34e-2)" "unprognostic (1.75e-1)" "unprognostic (4.06e-3)" "unprognostic (1.63e-1)" "unprognostic (5.65e-3)" "unprognostic (2.56e-1)" "unprognostic (1.33e-1)" "validated prognostic favorable (2.78e-11)" "validated prognostic favorable (9.45e-4)" "unprognostic (2.04e-1)" "unprognostic (4.25e-3)" "unprognostic (9.70e-3)" "unprognostic (1.83e-1)" "unprognostic (1.21e-1)" "unprognostic (1.37e-1)" "unprognostic (7.16e-2)" "unprognostic (8.14e-2)" "unprognostic (3.44e-1)" "unprognostic (1.11e-2)" "unprognostic (1.04e-1)" "unprognostic (1.08e-1)" "unprognostic (2.04e-2)" "unprognostic (2.99e-1)" ARAF ARAF1 ENSG00000078061 "A-Raf proto-oncogene, serine/threonine kinase" P10398 X 47561205-47571908 "Enzymes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066326, CAB080050, CAB080051" Approved Supported "Plasma membrane" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 36: Non-specific - mRNA processing" "Cluster 15: Non-specific - Protein processing" 115 "Plasma membrane" "CAB080050: , CAB080051: , HPA066326: " "unprognostic (2.66e-1)" "unprognostic (3.40e-2)" "unprognostic (6.52e-2)" "unprognostic (5.01e-2)" "unprognostic (1.41e-1)" "unprognostic (1.81e-1)" "unprognostic (1.80e-1)" "unprognostic (8.95e-2)" "unprognostic (2.45e-1)" "unprognostic (5.24e-2)" "potential prognostic favorable (3.98e-5)" "unprognostic (4.88e-2)" "unprognostic (1.72e-1)" "unprognostic (2.08e-2)" "unprognostic (2.65e-1)" "unprognostic (9.02e-2)" "unprognostic (1.19e-1)" "unprognostic (2.13e-2)" "unprognostic (7.89e-2)" "unprognostic (1.16e-1)" "unprognostic (1.27e-1)" "unprognostic (3.83e-2)" "unprognostic (2.22e-1)" "unprognostic (7.05e-2)" "unprognostic (2.89e-2)" "unprognostic (4.77e-2)" "unprognostic (3.79e-1)" "unprognostic (1.43e-1)" "unprognostic (1.45e-1)" "unprognostic (2.93e-2)" "unprognostic (1.75e-1)" ARAP1 CENTD2 ENSG00000186635 "ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1" Q96P48 11 72685069-72793599 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 138.9;Neutrophils: 515.8" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 98.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020703, HPA070383" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA 57000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 36: Choroid plexus - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 11 "Nucleoplasm, Plasma membrane" "Vesicles, Cytosol" "CAB020703: , HPA070383: " "unprognostic (5.50e-3)" "unprognostic (7.40e-2)" "unprognostic (5.87e-2)" "unprognostic (1.35e-1)" "unprognostic (1.27e-1)" "unprognostic (1.79e-1)" "unprognostic (1.25e-1)" "unprognostic (1.94e-2)" "unprognostic (4.81e-2)" "unprognostic (1.46e-1)" "unprognostic (9.81e-3)" "unprognostic (3.62e-2)" "potential prognostic favorable (3.82e-4)" "potential prognostic unfavorable (6.69e-4)" "unprognostic (7.39e-2)" "unprognostic (2.72e-2)" "unprognostic (1.12e-1)" "unprognostic (5.70e-2)" "unprognostic (1.06e-1)" "unprognostic (1.37e-2)" "unprognostic (6.55e-2)" "potential prognostic favorable (1.06e-4)" "unprognostic (5.63e-3)" "unprognostic (6.09e-2)" "unprognostic (6.94e-2)" "unprognostic (1.13e-2)" "unprognostic (9.60e-2)" "unprognostic (1.88e-1)" "unprognostic (1.42e-2)" "unprognostic (1.19e-2)" "unprognostic (8.19e-2)" ARAP2 "CENTD1, PARX" ENSG00000047365 "ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2" Q8WZ64 4 35948221-36244514 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 37.5" "Cell type enhanced" "Detected in many" "Astrocytes: 501.3;Bergmann glia: 862.9;Oligodendrocytes: 986.5;Pituicytes/FSCs: 558.2;Sertoli cells: 494.4" "Cell type enhanced" "Detected in all" "oligodendrocyte: 1219.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - T-cells, Skeletal muscle - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035925 Approved Approved "Actin filaments,Focal adhesion sites" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 78: Brain - Neuronal signaling" "Cluster 11: White matter - Signal transduction" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 2 "Focal adhesion sites" "Actin filaments" "HPA035925: " "unprognostic (4.98e-2)" "unprognostic (3.52e-2)" "unprognostic (5.83e-2)" "unprognostic (7.54e-2)" "unprognostic (4.09e-2)" "unprognostic (2.98e-2)" "unprognostic (3.79e-1)" "unprognostic (5.22e-2)" "potential prognostic favorable (7.64e-4)" "unprognostic (2.52e-2)" "potential prognostic favorable (6.88e-6)" "unprognostic (5.35e-3)" "unprognostic (1.51e-1)" "unprognostic (3.54e-2)" "unprognostic (6.54e-2)" "unprognostic (3.18e-2)" "unprognostic (4.29e-2)" "unprognostic (1.95e-2)" "unprognostic (1.51e-1)" "unprognostic (1.17e-1)" "unprognostic (1.06e-1)" "unprognostic (4.95e-3)" "potential prognostic unfavorable (1.32e-6)" "unprognostic (1.02e-1)" "unprognostic (4.72e-3)" "unprognostic (5.54e-2)" "unprognostic (3.97e-1)" "unprognostic (5.76e-2)" "unprognostic (1.47e-1)" "unprognostic (2.14e-2)" "unprognostic (1.53e-2)" ARAP3 "CENTD3, DRAG1, FLJ21065" ENSG00000120318 "ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3" Q8WWN8 5 141653401-141682230 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Lymphatic endothelial cells: 63.4;Neutrophil progenitors: 27.7;Neutrophils: 133.0;Prostatic hillock cells: 30.0;Retinal horizontal cells: 128.2;Vascular endothelial cells: 88.5" "Group enriched" "Detected in many" 6 "cerebellar inhibitory: 33.6;endothelial cell: 96.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "eosinophil: 3.3;neutrophil: 2.1" "Lineage enriched" "Detected in single" 7 "granulocytes: 3.3" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Pancreas - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Thyroid gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042887 Uncertain NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 31 "HPA042887: " "unprognostic (3.60e-3)" "unprognostic (2.68e-2)" "unprognostic (3.56e-2)" "potential prognostic unfavorable (6.14e-4)" "unprognostic (6.48e-2)" "unprognostic (8.19e-2)" "unprognostic (1.93e-1)" "unprognostic (3.79e-3)" "unprognostic (8.66e-2)" "unprognostic (7.80e-2)" "validated prognostic favorable (1.59e-5)" "validated prognostic favorable (9.59e-4)" "unprognostic (2.24e-2)" "unprognostic (3.04e-1)" "potential prognostic favorable (4.72e-4)" "unprognostic (1.51e-1)" "unprognostic (2.36e-1)" "unprognostic (7.41e-3)" "unprognostic (1.73e-1)" "unprognostic (4.97e-2)" "unprognostic (6.14e-2)" "unprognostic (1.43e-1)" "unprognostic (2.01e-3)" "unprognostic (3.71e-1)" "unprognostic (3.65e-1)" "unprognostic (1.35e-1)" "unprognostic (7.24e-2)" "unprognostic (2.96e-2)" "unprognostic (8.32e-2)" "unprognostic (1.49e-2)" "unprognostic (2.29e-1)" ARC "Arg3.1, KIAA0278" ENSG00000198576 "Activity regulated cytoskeleton associated protein" Q7LC44 8 142611049-142614479 "Predicted intracellular proteins" "Endocytosis, Transport" "Developmental protein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.4;pituitary gland: 67.6" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 63.8;Breast lactating cells: 98.6;Breast myoepithelial cells: 88.7;Decidual stromal cells: 58.4;Epididymal basal cells: 287.7;Epididymal principal cells: 135.8;Neuroendocrine cells: 82.6;Pituicytes/FSCs: 301.6" "Cell type enhanced" "Detected in many" "hippocampal CA1-3: 21.2;hippocampal CA4: 25.4" "Cancer enriched" "Detected in many" 13 "Glioblastoma Multiforme (TCGA): 59.7" "Group enriched" "Detected in all" 6 "cerebral cortex: 241.8;hippocampal formation: 70.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "Bone cancer: 9.7;Neuroblastoma: 21.6" "Adrenal gland - Adrenal medulla cells" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "basal ganglia: 32.0;cerebral cortex: 113.4;hippocampal formation: 64.7;olfactory bulb: 35.5" "HPA056430, CAB079013" Supported Approved Vesicles,Microtubules NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 29: Forebrain - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 6 "Vesicles, Microtubules" "CAB079013: , HPA056430: " "unprognostic (6.68e-2)" "unprognostic (1.83e-3)" "unprognostic (3.18e-2)" "unprognostic (1.00e-1)" "unprognostic (2.38e-1)" "unprognostic (1.72e-1)" "potential prognostic favorable (2.44e-6)" "unprognostic (2.06e-2)" "unprognostic (9.52e-2)" "unprognostic (9.76e-3)" "unprognostic (2.95e-2)" "unprognostic (5.63e-3)" "unprognostic (1.12e-1)" "unprognostic (1.77e-1)" ARCN1 COPD ENSG00000095139 "Archain 1" P48444 11 118572390-118603033 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" Dwarfism "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037573, HPA044874" Approved Approved "Golgi apparatus,Vesicles,Cytosol" NA NA 220000 "Cluster 33: Non-specific - ATP binding" "Cluster 70: Non-specific - Protein processing" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 24: Non-specific - Unknown function" "Cluster 78: Plasma cells - Antibody production & ER-stress response" 45 Vesicles "Golgi apparatus, Cytosol" "HPA037573: , HPA044874: " "unprognostic (5.45e-2)" "unprognostic (2.59e-3)" "unprognostic (3.71e-1)" "unprognostic (2.93e-2)" "unprognostic (2.84e-1)" "potential prognostic unfavorable (9.44e-4)" "unprognostic (7.90e-2)" "unprognostic (1.08e-1)" "unprognostic (3.15e-3)" "unprognostic (1.14e-2)" "potential prognostic favorable (1.12e-4)" "unprognostic (3.63e-2)" "unprognostic (1.92e-1)" "potential prognostic unfavorable (5.79e-6)" "unprognostic (5.52e-2)" "potential prognostic unfavorable (5.31e-4)" "unprognostic (5.20e-3)" "unprognostic (1.41e-1)" "unprognostic (9.40e-2)" "unprognostic (1.19e-1)" "unprognostic (1.36e-2)" "unprognostic (3.34e-3)" "unprognostic (1.94e-1)" "unprognostic (2.90e-1)" "unprognostic (7.10e-2)" "unprognostic (7.93e-3)" "unprognostic (1.65e-2)" "unprognostic (1.50e-1)" "unprognostic (2.52e-1)" "unprognostic (3.22e-2)" "unprognostic (2.16e-1)" AREG "AR, AREGB, SDGF" ENSG00000109321 Amphiregulin P15514 4 74445136-74455005 "Cancer-related genes, Human disease related genes, Predicted membrane proteins" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 122.6;placenta: 308.9;urinary bladder: 135.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 3209.8;Breast hormone-responsive cells: 1337.5;cDC: 1501.6;Esophageal apical cells: 1903.7;Hematopoietic stem cells: 1321.3;Innate lymphoid cells: 3588.5;Mast cells: 5140.6;monocytes: 1830.5;NK-cells: 1412.3;Ocular epithelial cells: 2320.0;Thymocytes: 1815.0;Urothelial cells: 1489.4" "Cell type enriched" "Detected in some" 17 "leukocyte: 41.6" "Cancer enhanced" "Detected in many" "Rectum Adenocarcinoma (TCGA): 166.5" "Region enhanced" "Detected in some" "choroid plexus: 3.2" "Group enriched" "Detected in some" 11 "basophil: 11.0;eosinophil: 11.8;NK-cell: 3.8" "Group enriched" "Detected in many" 10 "granulocytes: 11.8;NK-cells: 3.8" "Cancer enhanced" "Detected in many" "Bile duct cancer: 543.3" "Colon - Neutrophils, Testis - Early spermatids" "Region enriched" "Detected in single" 4 "olfactory bulb: 1.2" "Low region specificity" "Detected in all" "HPA008720, CAB023519" Approved Approved Mitochondria NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 4 Mitochondria "CAB023519: , HPA008720: " "unprognostic (8.37e-2)" "unprognostic (3.90e-2)" "unprognostic (1.08e-1)" "unprognostic (1.13e-1)" "unprognostic (5.19e-2)" "unprognostic (1.94e-3)" "unprognostic (1.27e-3)" "potential prognostic unfavorable (6.34e-5)" "unprognostic (1.31e-3)" "unprognostic (3.98e-2)" "unprognostic (3.01e-3)" "unprognostic (2.72e-1)" "unprognostic (1.09e-2)" "potential prognostic unfavorable (8.51e-4)" "unprognostic (3.39e-2)" "potential prognostic unfavorable (8.29e-5)" "unprognostic (3.73e-3)" "unprognostic (5.12e-2)" "unprognostic (1.29e-1)" "validated prognostic unfavorable (6.75e-4)" "validated prognostic unfavorable (4.30e-4)" "unprognostic (3.09e-2)" "unprognostic (2.52e-1)" "potential prognostic favorable (2.36e-4)" "unprognostic (4.21e-1)" "unprognostic (6.66e-2)" "unprognostic (1.32e-1)" "unprognostic (1.06e-1)" AREL1 "FIEL1, KIAA0317" ENSG00000119682 "Apoptosis resistant E3 ubiquitin protein ligase 1" O15033 14 74653437-74713117 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophil progenitors: 145.2;Neutrophils: 438.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051306, CAB080652, CAB080653, CAB080656, CAB080657, CAB080658" Uncertain Approved Vesicles,Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 9 Vesicles Cytosol "CAB080652: , CAB080653: , CAB080656: , CAB080657: , CAB080658: , HPA051306: " "unprognostic (1.20e-2)" "unprognostic (6.11e-2)" "unprognostic (2.42e-2)" "unprognostic (1.58e-1)" "unprognostic (2.54e-1)" "unprognostic (1.12e-1)" "unprognostic (6.58e-3)" "unprognostic (6.85e-2)" "unprognostic (1.99e-1)" "potential prognostic favorable (2.68e-6)" "unprognostic (6.27e-2)" "unprognostic (1.89e-2)" "unprognostic (4.23e-2)" "unprognostic (1.87e-1)" "unprognostic (4.42e-1)" "unprognostic (1.54e-1)" "unprognostic (1.15e-1)" "unprognostic (6.74e-3)" "unprognostic (1.02e-1)" "unprognostic (1.42e-1)" "unprognostic (6.71e-2)" "unprognostic (1.48e-1)" "unprognostic (5.57e-3)" "unprognostic (5.15e-3)" "unprognostic (2.00e-1)" "unprognostic (5.98e-2)" "unprognostic (4.19e-1)" "unprognostic (2.84e-2)" "unprognostic (4.72e-2)" ARF1 ENSG00000143761 "ADP ribosylation factor 1" P84077 1 228082708-228099212 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1289.1;Platelets: 1412.8;Syncytiotrophoblasts: 897.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB007742 Uncertain Approved "Plasma membrane,Cytosol" NA NA 20000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 24: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 47: Platelets - Hemostasis" 35 Cytosol "Plasma membrane" "CAB007742: " "unprognostic (3.09e-1)" "unprognostic (3.57e-2)" "unprognostic (1.04e-1)" "unprognostic (1.24e-3)" "unprognostic (6.02e-2)" "unprognostic (4.63e-2)" "unprognostic (3.98e-2)" "unprognostic (6.94e-2)" "unprognostic (7.01e-3)" "unprognostic (2.51e-1)" "unprognostic (2.99e-2)" "unprognostic (3.00e-2)" "unprognostic (1.01e-1)" "unprognostic (5.06e-2)" "unprognostic (1.99e-2)" "unprognostic (3.87e-2)" "potential prognostic unfavorable (3.53e-4)" "unprognostic (1.26e-2)" "unprognostic (5.78e-1)" "unprognostic (5.58e-2)" "unprognostic (1.27e-1)" "unprognostic (8.12e-2)" "unprognostic (1.06e-1)" "unprognostic (2.06e-1)" "unprognostic (7.05e-3)" "unprognostic (2.14e-1)" "unprognostic (2.04e-1)" "unprognostic (2.33e-1)" "unprognostic (3.05e-1)" "unprognostic (3.48e-2)" "unprognostic (2.06e-1)" ARF3 ENSG00000134287 "ADP ribosylation factor 3" P61204 12 48935723-48957487 "Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 271.2" "Cell type enhanced" "Detected in many" "Late spermatids: 31.0;Megakaryocytes: 18.5;Platelets: 36.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Colon - Macrophages, Spleen - Macrophages, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 35: Neurons - Synaptic function & neurogenesis" 18 "unprognostic (3.14e-1)" "unprognostic (1.24e-2)" "unprognostic (2.68e-1)" "potential prognostic unfavorable (1.28e-4)" "unprognostic (5.78e-2)" "unprognostic (2.74e-2)" "unprognostic (4.29e-2)" "unprognostic (1.68e-1)" "unprognostic (1.64e-3)" "unprognostic (6.67e-3)" "potential prognostic favorable (3.07e-5)" "unprognostic (6.75e-2)" "unprognostic (7.05e-2)" "unprognostic (9.86e-3)" "unprognostic (5.35e-3)" "unprognostic (4.16e-3)" "unprognostic (3.65e-3)" "unprognostic (9.17e-2)" "unprognostic (1.11e-1)" "unprognostic (1.64e-1)" "unprognostic (1.31e-2)" "unprognostic (8.98e-2)" "unprognostic (3.60e-2)" "unprognostic (1.32e-1)" "unprognostic (1.85e-1)" "unprognostic (7.16e-3)" "unprognostic (1.64e-1)" "unprognostic (1.95e-1)" "unprognostic (8.34e-2)" "unprognostic (1.40e-1)" "unprognostic (9.82e-2)" ARF4 ARF2 ENSG00000168374 "ADP ribosylation factor 4" P18085 3 57571363-57598220 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1191.5;Syncytiotrophoblasts: 946.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 4200000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 22: Epididymis - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 41 "unprognostic (4.28e-2)" "unprognostic (3.51e-2)" "unprognostic (1.25e-2)" "unprognostic (2.85e-3)" "unprognostic (2.38e-1)" "unprognostic (7.43e-2)" "unprognostic (1.09e-1)" "unprognostic (2.43e-2)" "unprognostic (8.13e-2)" "unprognostic (1.74e-2)" "potential prognostic favorable (4.12e-4)" "unprognostic (7.39e-2)" "unprognostic (9.01e-2)" "validated prognostic unfavorable (3.71e-6)" "validated prognostic unfavorable (1.28e-4)" "unprognostic (7.05e-3)" "unprognostic (1.50e-3)" "unprognostic (4.85e-2)" "unprognostic (1.01e-1)" "unprognostic (8.05e-2)" "unprognostic (5.69e-2)" "unprognostic (1.54e-2)" "unprognostic (3.59e-2)" "unprognostic (2.45e-1)" "unprognostic (4.70e-2)" "unprognostic (2.28e-1)" "unprognostic (2.12e-1)" "unprognostic (1.96e-1)" "unprognostic (2.33e-1)" "potential prognostic unfavorable (1.56e-4)" "unprognostic (1.28e-1)" ARF5 ENSG00000004059 "ADP ribosylation factor 5" P84085 7 127588386-127591700 "Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 280.4;Oocytes: 262.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 5100000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 39: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 33 "unprognostic (8.50e-2)" "unprognostic (7.59e-2)" "unprognostic (1.24e-2)" "unprognostic (2.60e-1)" "unprognostic (1.17e-1)" "unprognostic (1.08e-1)" "unprognostic (5.19e-3)" "unprognostic (2.40e-1)" "unprognostic (7.15e-2)" "unprognostic (2.08e-3)" "unprognostic (3.65e-2)" "unprognostic (1.17e-2)" "unprognostic (4.72e-2)" "unprognostic (5.43e-3)" "potential prognostic unfavorable (2.01e-4)" "unprognostic (1.15e-1)" "unprognostic (6.83e-3)" "unprognostic (1.81e-2)" "unprognostic (1.84e-1)" "unprognostic (2.51e-2)" "unprognostic (1.23e-1)" "unprognostic (1.11e-1)" "unprognostic (4.46e-2)" "unprognostic (3.12e-1)" "unprognostic (2.76e-2)" "unprognostic (3.44e-1)" "unprognostic (3.96e-1)" "unprognostic (2.56e-1)" "unprognostic (4.59e-2)" "unprognostic (2.26e-1)" "unprognostic (6.88e-2)" ARF6 ENSG00000165527 "ADP ribosylation factor 6" P62330 14 49893079-49897054 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Cell cycle, Cell division, Differentiation, Neurogenesis, Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Esophageal apical cells: 2405.6" "Cell type enhanced" "Detected in all" "leukocyte: 69.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002778, CAB079914" Approved Supported Cytosol NA NA 280000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 84: Apical squamous epithelium - Cornification" 104 Cytosol "CAB002778: , CAB079914: " "unprognostic (1.20e-2)" "unprognostic (1.15e-1)" "unprognostic (2.57e-3)" "unprognostic (3.33e-1)" "unprognostic (4.25e-2)" "unprognostic (8.97e-2)" "unprognostic (3.04e-1)" "unprognostic (1.80e-1)" "unprognostic (2.73e-1)" "potential prognostic unfavorable (9.10e-4)" "potential prognostic favorable (7.64e-5)" "unprognostic (1.24e-1)" "unprognostic (2.73e-1)" "unprognostic (1.85e-3)" "unprognostic (2.69e-1)" "unprognostic (1.28e-2)" "unprognostic (5.14e-3)" "unprognostic (1.85e-1)" "unprognostic (9.40e-2)" "unprognostic (4.80e-3)" "unprognostic (3.57e-1)" "potential prognostic unfavorable (5.66e-5)" "unprognostic (7.84e-2)" "unprognostic (1.21e-1)" "unprognostic (3.01e-1)" "unprognostic (4.20e-2)" "unprognostic (3.80e-1)" "unprognostic (2.44e-2)" "unprognostic (8.46e-2)" "unprognostic (3.69e-1)" "unprognostic (1.07e-1)" ARFGAP1 "ARF1GAP, bA261N11.3, FLJ10767" ENSG00000101199 "ADP ribosylation factor GTPase activating protein 1" Q8N6T3 20 63272785-63289790 "Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Somatotrophs: 90.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051019, HPA056273" Approved Approved "Nuclear membrane,Golgi apparatus,Vesicles,Primary cilium,Cytosol" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 64: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 16 "Golgi apparatus" "Nuclear membrane, Vesicles, Primary cilium, Cytosol" "HPA051019: , HPA056273: " "unprognostic (5.44e-2)" "unprognostic (5.30e-3)" "unprognostic (1.03e-1)" "unprognostic (8.51e-3)" "unprognostic (3.62e-1)" "unprognostic (1.87e-1)" "unprognostic (3.91e-1)" "unprognostic (6.00e-3)" "unprognostic (1.73e-2)" "unprognostic (5.94e-2)" "potential prognostic unfavorable (1.96e-5)" "unprognostic (1.94e-3)" "unprognostic (1.17e-1)" "potential prognostic unfavorable (2.38e-6)" "unprognostic (3.49e-2)" "unprognostic (3.64e-1)" "unprognostic (1.05e-2)" "unprognostic (6.76e-2)" "unprognostic (1.50e-2)" "unprognostic (2.11e-1)" "unprognostic (3.74e-2)" "potential prognostic favorable (6.99e-4)" "potential prognostic unfavorable (5.73e-4)" "unprognostic (1.63e-2)" "unprognostic (1.49e-2)" "potential prognostic favorable (2.12e-4)" "unprognostic (1.34e-1)" "unprognostic (9.17e-2)" "unprognostic (1.67e-1)" "unprognostic (1.31e-2)" "unprognostic (1.33e-1)" ARFGAP2 "FLJ14576, IRZ, Zfp289, ZNF289" ENSG00000149182 "ADP ribosylation factor GTPase activating protein 2" Q8N6H7 11 47164299-47177125 "Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016649, HPA018152" Enhanced Supported "Golgi apparatus" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 24: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 24: Non-specific - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 13 "Golgi apparatus" "HPA016649: , HPA018152: " "unprognostic (1.23e-1)" "unprognostic (2.48e-1)" "unprognostic (4.82e-2)" "unprognostic (1.23e-1)" "unprognostic (4.01e-3)" "unprognostic (1.42e-2)" "unprognostic (1.10e-2)" "unprognostic (1.47e-2)" "unprognostic (4.36e-1)" "unprognostic (5.97e-3)" "potential prognostic favorable (1.19e-6)" "unprognostic (1.47e-3)" "potential prognostic favorable (3.83e-7)" "unprognostic (2.05e-2)" "unprognostic (5.55e-2)" "unprognostic (2.53e-1)" "unprognostic (8.92e-3)" "unprognostic (2.61e-1)" "unprognostic (1.09e-1)" "unprognostic (1.68e-1)" "unprognostic (8.42e-2)" "unprognostic (3.83e-1)" "unprognostic (8.87e-2)" "unprognostic (2.68e-1)" "unprognostic (1.62e-1)" "unprognostic (7.61e-2)" "unprognostic (1.94e-1)" "unprognostic (1.40e-1)" "unprognostic (1.91e-1)" "unprognostic (2.97e-1)" "unprognostic (1.15e-3)" ARFGAP3 ARFGAP1 ENSG00000242247 "ADP ribosylation factor GTPase activating protein 3" Q9NP61 22 42796502-42858106 "Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Prostate glandular cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000638 Approved Supported "Golgi apparatus,Cytosol" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 70: Non-specific - Protein processing" "Cluster 55: Non-specific - Transcription" "Cluster 66: Non-specific - Mitochondria" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 37 Cytosol "Golgi apparatus" "HPA000638: " "unprognostic (2.78e-2)" "unprognostic (3.98e-2)" "unprognostic (5.52e-2)" "unprognostic (1.93e-1)" "unprognostic (7.46e-2)" "unprognostic (1.88e-1)" "unprognostic (4.77e-2)" "unprognostic (1.88e-1)" "unprognostic (2.35e-2)" "unprognostic (2.42e-1)" "validated prognostic favorable (8.04e-6)" "validated prognostic favorable (5.50e-4)" "unprognostic (1.41e-2)" "unprognostic (8.93e-3)" "unprognostic (3.03e-3)" "unprognostic (1.76e-1)" "unprognostic (1.75e-1)" "unprognostic (1.22e-1)" "unprognostic (6.15e-2)" "unprognostic (7.80e-2)" "unprognostic (9.67e-2)" "unprognostic (1.07e-2)" "unprognostic (2.36e-2)" "unprognostic (5.98e-2)" "unprognostic (2.35e-1)" "unprognostic (1.21e-1)" "unprognostic (2.79e-1)" "unprognostic (8.53e-2)" "unprognostic (1.35e-1)" "unprognostic (1.51e-3)" "unprognostic (2.29e-2)" ARFGEF1 "ARFGEP1, BIG1, DKFZP434L057, p200" ENSG00000066777 "ADP ribosylation factor guanine nucleotide exchange factor 1" Q9Y6D6 8 67173511-67343781 "Disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Guanine-nucleotide releasing factor" "Autism spectrum disorder, Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 1700.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023399, HPA023822" Supported Supported Enhanced "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 42: Retina - Visual perception" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 40: Non-specific - Unknown function" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 48 "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA023399: , HPA023822: " "unprognostic (4.33e-2)" "unprognostic (1.07e-2)" "unprognostic (7.76e-2)" "unprognostic (1.09e-2)" "unprognostic (1.61e-1)" "unprognostic (3.55e-1)" "unprognostic (1.92e-1)" "unprognostic (7.63e-2)" "unprognostic (8.77e-2)" "potential prognostic unfavorable (2.55e-4)" "potential prognostic favorable (5.62e-7)" "unprognostic (5.01e-3)" "unprognostic (3.90e-2)" "unprognostic (1.40e-1)" "unprognostic (6.96e-2)" "unprognostic (1.11e-1)" "unprognostic (7.34e-2)" "unprognostic (9.42e-2)" "unprognostic (2.85e-1)" "unprognostic (2.50e-2)" "unprognostic (6.84e-3)" "unprognostic (1.98e-3)" "unprognostic (5.85e-3)" "unprognostic (1.43e-1)" "unprognostic (9.96e-3)" "unprognostic (2.26e-1)" "unprognostic (2.27e-2)" "unprognostic (3.03e-1)" "unprognostic (2.77e-1)" "unprognostic (7.51e-2)" "unprognostic (6.48e-2)" ARFGEF2 BIG2 ENSG00000124198 "ADP ribosylation factor guanine nucleotide exchange factor 2" Q9Y6D5 20 48921711-49036693 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Guanine-nucleotide releasing factor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 76.7" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 407.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026078, CAB026382" Supported Supported "Golgi apparatus" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 14: Neurons - Synaptic function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 43 "Golgi apparatus" "CAB026382: , HPA026078: " "unprognostic (7.24e-2)" "unprognostic (9.45e-2)" "unprognostic (7.96e-2)" "unprognostic (5.62e-2)" "unprognostic (1.41e-1)" "unprognostic (8.17e-2)" "unprognostic (1.93e-1)" "unprognostic (3.14e-2)" "unprognostic (1.23e-2)" "unprognostic (1.59e-2)" "potential prognostic favorable (1.12e-6)" "unprognostic (1.14e-2)" "unprognostic (5.80e-2)" "unprognostic (1.22e-1)" "unprognostic (1.97e-2)" "unprognostic (4.39e-1)" "unprognostic (2.71e-1)" "unprognostic (1.25e-1)" "unprognostic (5.72e-2)" "unprognostic (9.57e-3)" "potential prognostic unfavorable (9.45e-5)" "unprognostic (7.49e-3)" "unprognostic (4.19e-2)" "unprognostic (1.49e-1)" "potential prognostic favorable (3.99e-4)" "unprognostic (1.33e-2)" "unprognostic (2.37e-1)" "unprognostic (1.29e-1)" "unprognostic (5.36e-2)" "unprognostic (6.87e-2)" "unprognostic (2.29e-2)" ARFGEF3 "BIG3, C6orf92, dJ171N11.1, KIAA1244, PPP1R33" ENSG00000112379 "ARFGEF family member 3" Q5TH69 6 138161939-138344663 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.1;salivary gland: 17.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 481.5;Neuroendocrine cells: 391.9;Oligodendrocytes: 480.8;Pancreatic islet cells: 489.5;Prostatic club cells: 349.1;Prostatic glandular cells: 625.8;Salivary acinar cells: 547.5;Somatotrophs: 610.5;Thyrotrophs: 391.6;Transitional alveolar cells: 461.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 34.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "breast cancer: 13.8;prostate cancer: 45.9" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Breast - Breast glandular cells, Liver - Vascular endothelial cells, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036350 Uncertain NA NA "Cluster 70: Non-specific - Protein processing" "Cluster 34: Non-specific - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 3 "HPA036350: " "unprognostic (1.38e-2)" "potential prognostic unfavorable (2.11e-4)" "unprognostic (6.76e-2)" "unprognostic (3.94e-3)" "unprognostic (2.23e-2)" "unprognostic (4.08e-2)" "unprognostic (1.52e-3)" "unprognostic (5.96e-2)" "unprognostic (1.06e-1)" "unprognostic (3.99e-2)" "unprognostic (1.17e-3)" "unprognostic (1.48e-2)" "unprognostic (3.09e-1)" "unprognostic (1.79e-1)" "unprognostic (2.43e-2)" "unprognostic (1.31e-2)" "unprognostic (4.71e-2)" "unprognostic (1.88e-1)" "unprognostic (9.50e-2)" "unprognostic (2.63e-2)" "unprognostic (4.80e-2)" "unprognostic (1.51e-1)" "unprognostic (1.08e-1)" "unprognostic (7.98e-2)" ARFIP1 HSU52521 ENSG00000164144 "ADP ribosylation factor interacting protein 1" P53367 4 152779937-152918463 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005080, HPA037375, HPA063759" Enhanced Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 34 "Golgi apparatus, Vesicles" Nucleoplasm "CAB005080: , HPA037375: , HPA063759: " "unprognostic (7.40e-2)" "unprognostic (3.80e-2)" "unprognostic (1.31e-2)" "unprognostic (7.34e-2)" "potential prognostic favorable (4.61e-5)" "unprognostic (3.85e-3)" "unprognostic (2.44e-1)" "unprognostic (5.94e-2)" "unprognostic (2.83e-1)" "unprognostic (4.57e-2)" "validated prognostic favorable (7.21e-9)" "validated prognostic favorable (8.37e-4)" "unprognostic (2.61e-2)" "unprognostic (1.11e-2)" "unprognostic (1.41e-1)" "unprognostic (4.13e-2)" "unprognostic (1.52e-2)" "unprognostic (1.84e-2)" "unprognostic (8.87e-3)" "unprognostic (1.92e-2)" "unprognostic (3.10e-3)" "unprognostic (2.86e-2)" "unprognostic (2.04e-1)" "unprognostic (1.77e-2)" "unprognostic (6.06e-2)" "unprognostic (3.36e-1)" "unprognostic (1.44e-1)" "unprognostic (1.39e-1)" "unprognostic (1.36e-1)" "unprognostic (9.18e-2)" "unprognostic (6.92e-3)" ARFIP2 POR1 ENSG00000132254 "ADP ribosylation factor interacting protein 2" P53365 11 6474683-6481479 "Predicted intracellular proteins" Autophagy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 114.1;Goblet cells: 124.2;Syncytiotrophoblasts: 137.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032985, HPA038156, HPA038157" Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 70: Non-specific - Protein processing" "Cluster 23: Choroid plexus - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 70: Intestinal goblet cells - Mucin production" 64 "Nucleoplasm, Nucleoli, Golgi apparatus" "CAB032985: , HPA038156: , HPA038157: " "unprognostic (5.06e-2)" "unprognostic (2.13e-1)" "unprognostic (7.02e-2)" "unprognostic (5.02e-3)" "unprognostic (4.66e-2)" "unprognostic (6.21e-2)" "unprognostic (3.41e-2)" "unprognostic (2.73e-2)" "unprognostic (1.86e-1)" "unprognostic (4.28e-2)" "potential prognostic favorable (5.63e-5)" "unprognostic (5.54e-2)" "unprognostic (1.17e-1)" "potential prognostic unfavorable (1.53e-4)" "unprognostic (1.88e-3)" "unprognostic (4.24e-1)" "unprognostic (4.45e-2)" "unprognostic (4.98e-2)" "unprognostic (4.90e-1)" "unprognostic (4.83e-2)" "unprognostic (8.74e-2)" "unprognostic (5.15e-2)" "unprognostic (1.77e-2)" "unprognostic (1.60e-1)" "unprognostic (8.43e-3)" "unprognostic (6.89e-2)" "unprognostic (2.22e-1)" "unprognostic (3.30e-2)" "unprognostic (1.16e-1)" "unprognostic (2.59e-2)" "unprognostic (1.20e-1)" ARFRP1 "ARL18, ARP, Arp1" ENSG00000101246 "ADP ribosylation factor related protein 1" Q13795 20 63698642-63708025 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047028, HPA050634" Approved Supported "Golgi apparatus" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 97: Non-specific - Cellular respiration" 4 "Golgi apparatus" "HPA047028: , HPA050634: " "unprognostic (4.16e-2)" "unprognostic (1.85e-1)" "unprognostic (1.99e-2)" "unprognostic (1.92e-1)" "unprognostic (2.18e-1)" "unprognostic (1.10e-1)" "unprognostic (1.98e-3)" "unprognostic (6.60e-2)" "unprognostic (9.05e-2)" "unprognostic (8.08e-2)" "unprognostic (7.22e-3)" "unprognostic (5.43e-2)" "unprognostic (5.13e-2)" "potential prognostic unfavorable (7.31e-5)" "unprognostic (9.83e-2)" "unprognostic (1.66e-2)" "unprognostic (1.17e-1)" "unprognostic (1.71e-2)" "unprognostic (1.12e-1)" "unprognostic (1.34e-2)" "unprognostic (1.23e-1)" "unprognostic (2.84e-2)" "potential prognostic unfavorable (9.14e-4)" "unprognostic (2.50e-2)" "unprognostic (9.08e-2)" "unprognostic (5.78e-2)" "unprognostic (1.34e-1)" "unprognostic (2.27e-1)" "unprognostic (1.79e-1)" "unprognostic (1.66e-1)" "unprognostic (1.20e-1)" ARG1 ENSG00000118520 "Arginase 1" P05089 6 131470832-131584332 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Adaptive immunity, Arginine metabolism, Immunity, Innate immunity, Urea cycle" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "liver: 1124.7" "Group enriched" "Detected in many" 38 "Hepatocytes: 1282.8;Neutrophil progenitors: 1426.7;Neutrophils: 943.6" "Cell type enhanced" "Detected in many" "deep-layer corticothalamic and 6b: 14.6" "Cancer enriched" "Detected in some" 36 "Liver Hepatocellular Carcinoma (TCGA): 293.8" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 5 "neutrophil: 45.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 45.0" "Group enriched" "Detected in some" 6 "Leukemia: 1.6;liver cancer: 1.7" "Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Liver - Hepatocytes, Lung - Neutrophils_2, Pituitary gland - Neutrophils, Skeletal muscle - Neutrophils, Skin - Keratinocyte (granular), Spleen - Neutrophils_2, Thyroid gland - Neutrophils" "Region enhanced" "Detected in single" "cerebellum: 2.4" "Low region specificity" "Detected in some" "HPA003595, CAB009434, HPA024006, CAB056159, CAB080011" Enhanced NA NA 11000000 "Cluster 4: Neutrophils - Degranulation" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 2: Neurons - Nucleosome" "Cluster 47: Leukemia - Hemostasis" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 3 "CAB009434: , CAB056159: , CAB080011: , HPA003595: , HPA024006: " "unprognostic (1.01e-1)" "unprognostic (5.55e-2)" "unprognostic (2.00e-3)" "unprognostic (2.07e-2)" ARG2 ENSG00000081181 "Arginase 2" P78540 14 67619920-67651708 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Adaptive immunity, Arginine metabolism, Immunity, Innate immunity, Urea cycle" Hydrolase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 206.5;prostate: 101.8;thyroid gland: 97.9" "Cell type enhanced" "Detected in many" "Breast lactating cells: 357.4;Esophageal apical cells: 388.9;Oocytes: 432.9;Prostatic glandular cells: 355.5;Syncytiotrophoblasts: 901.3;Thymic myoid cells: 284.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 176.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA000663, CAB009435" Enhanced Supported Mitochondria NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 3 Mitochondria "CAB009435: , HPA000663: " "unprognostic (1.33e-1)" "unprognostic (4.96e-2)" "unprognostic (1.41e-1)" "unprognostic (1.31e-1)" "unprognostic (2.57e-1)" "unprognostic (6.44e-2)" "unprognostic (7.18e-2)" "unprognostic (5.29e-2)" "unprognostic (3.77e-2)" "unprognostic (3.66e-1)" "unprognostic (2.72e-2)" "potential prognostic favorable (3.17e-6)" "unprognostic (2.29e-1)" "unprognostic (9.47e-3)" "unprognostic (2.63e-1)" "unprognostic (1.06e-2)" "unprognostic (2.24e-1)" "unprognostic (3.42e-2)" "potential prognostic favorable (4.03e-4)" "unprognostic (9.00e-2)" "unprognostic (6.02e-2)" "unprognostic (1.13e-2)" "unprognostic (4.21e-2)" "unprognostic (2.27e-2)" "unprognostic (1.09e-2)" "unprognostic (5.34e-2)" "potential prognostic unfavorable (5.33e-4)" "unprognostic (1.28e-1)" "unprognostic (1.24e-1)" "unprognostic (3.18e-1)" "unprognostic (6.85e-2)" ARGFX ENSG00000186103 "Arginine-fifty homeobox" A6NJG6 3 121567949-121590622 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "bone marrow: 1.0" "Cell type enriched" "Detected in some" 4 "Cardiomyocytes: 49.3" "Cell type enhanced" "Detected in some" "upper-layer intratelencephalic: 2.7" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 2.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes" HPA043049 Uncertain NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 40: Non-specific - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" "HPA043049: " "unprognostic (6.53e-2)" "unprognostic (1.36e-2)" "unprognostic (6.74e-2)" "unprognostic (3.86e-2)" "unprognostic (1.22e-1)" ARGLU1 FLJ10154 ENSG00000134884 "Arginine and glutamate rich 1" Q9NWB6 13 106541673-106568137 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, Transcription, Transcription regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pancreas - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034962, HPA056792" Supported Enhanced Nucleoplasm,Mitochondria,Cytosol No No "Cluster 22: Eosinophils - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 35 Nucleoplasm "Mitochondria, Cytosol" "HPA034962: , HPA056792: " "unprognostic (3.12e-2)" "unprognostic (3.64e-1)" "unprognostic (2.40e-1)" "unprognostic (3.12e-3)" "unprognostic (1.55e-2)" "unprognostic (1.92e-1)" "unprognostic (1.26e-2)" "unprognostic (6.25e-3)" "unprognostic (2.36e-1)" "unprognostic (2.48e-1)" "unprognostic (7.72e-2)" "unprognostic (1.37e-2)" "unprognostic (2.49e-2)" "potential prognostic unfavorable (2.98e-4)" "unprognostic (3.20e-1)" "unprognostic (3.38e-1)" "unprognostic (2.92e-1)" "unprognostic (4.17e-3)" "unprognostic (3.97e-2)" "unprognostic (2.14e-1)" "unprognostic (3.55e-1)" "potential prognostic favorable (6.88e-4)" "unprognostic (5.45e-2)" "unprognostic (1.31e-1)" "unprognostic (3.22e-2)" "unprognostic (2.95e-2)" "unprognostic (4.00e-2)" "unprognostic (7.67e-2)" "unprognostic (3.81e-2)" "unprognostic (3.55e-2)" "unprognostic (6.50e-2)" ARHGAP1 "CDC42GAP, p50rhoGAP, RhoGAP" ENSG00000175220 "Rho GTPase activating protein 1" Q07960 11 46677080-46700619 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 147.2" "Cell type enhanced" "Detected in all" "oligodendrocyte: 147.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Prostate - Smooth muscle cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004689, HPA008285" Approved Approved Supported "Vesicles,Primary cilium,Cytosol" NA NA 3900000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 11: White matter - Signal transduction" "Cluster 24: Non-specific - Unknown function" "Cluster 110: Mural cells - ECM organization" 29 Cytosol "Vesicles, Primary cilium" "HPA004689: , HPA008285: " "unprognostic (8.69e-3)" "unprognostic (1.51e-1)" "unprognostic (1.59e-1)" "unprognostic (5.56e-2)" "unprognostic (1.35e-2)" "unprognostic (1.77e-3)" "unprognostic (6.97e-3)" "unprognostic (7.01e-2)" "unprognostic (1.93e-1)" "unprognostic (4.41e-2)" "unprognostic (3.28e-2)" "unprognostic (2.57e-1)" "unprognostic (9.01e-3)" "potential prognostic unfavorable (1.87e-4)" "unprognostic (1.10e-1)" "unprognostic (1.21e-2)" "potential prognostic unfavorable (5.47e-7)" "unprognostic (2.26e-2)" "unprognostic (5.06e-2)" "unprognostic (2.57e-2)" "unprognostic (7.64e-2)" "unprognostic (7.06e-2)" "unprognostic (4.33e-1)" "unprognostic (3.01e-1)" "unprognostic (5.99e-2)" "unprognostic (8.47e-2)" "unprognostic (2.18e-2)" "unprognostic (1.05e-2)" "unprognostic (3.01e-1)" "unprognostic (8.58e-2)" "unprognostic (7.68e-2)" ARHGAP10 "FLJ20896, FLJ41791, GRAF2" ENSG00000071205 "Rho GTPase activating protein 10" A1A4S6 4 147732063-148072776 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 859.9;Fibro-adipogenic progenitors: 522.1;Innate lymphoid cells: 632.1;Leydig cells: 859.0;Myonuclei: 546.5;Pericytes: 753.2;Peritubular myoid cells: 685.9;Rod photoreceptor cells: 576.4;Vascular smooth muscle cells: 565.4" "Group enriched" "Detected in all" 4 "fibroblast: 654.5;pericyte: 1098.7;vascular associated smooth muscle cell: 1433.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 16.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Kidney - Fibroblasts, Prostate - Smooth muscle cells, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebellum: 110.0" HPA039589 Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 110: Mural cells - ECM organization" 9 Nucleoplasm "Nuclear membrane, Cytosol" "HPA039589: " "unprognostic (3.68e-2)" "unprognostic (8.37e-2)" "unprognostic (1.03e-1)" "unprognostic (2.98e-1)" "unprognostic (4.63e-2)" "unprognostic (1.26e-1)" "unprognostic (2.89e-1)" "unprognostic (7.80e-2)" "unprognostic (3.94e-2)" "unprognostic (6.23e-2)" "potential prognostic favorable (6.42e-11)" "unprognostic (1.73e-3)" "unprognostic (8.73e-2)" "unprognostic (1.12e-1)" "unprognostic (1.04e-3)" "validated prognostic unfavorable (2.14e-4)" "validated prognostic unfavorable (8.08e-4)" "unprognostic (3.69e-2)" "unprognostic (2.13e-1)" "unprognostic (3.26e-1)" "unprognostic (7.28e-2)" "unprognostic (3.43e-1)" "unprognostic (3.39e-3)" "unprognostic (2.52e-2)" "unprognostic (1.47e-3)" "unprognostic (1.87e-2)" "unprognostic (1.27e-2)" "unprognostic (2.35e-3)" "unprognostic (8.77e-2)" "unprognostic (1.36e-1)" "unprognostic (3.05e-2)" ARHGAP11A KIAA0013 ENSG00000198826 "Rho GTPase activating protein 11A" Q6P4F7 15 32615144-32639941 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 22.5;lymphoid tissue: 24.2" "Cell type enhanced" "Detected in some" "Erythrocyte progenitors: 3.4;Megakaryocyte progenitors: 3.1;Microglia: 2.1;Monocyte progenitors: 4.7;Neutrophil progenitors: 1.9;Oligodendrocytes: 1.3;Papillary tip epithelial cells: 2.0;Renal collecting duct principal cells: 1.4;Renal connecting tubule cells: 1.0" "Cell type enhanced" "Detected in many" "leukocyte: 6.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Prostate - Macrophages, Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040830, HPA066481" Enhanced Approved Nucleoli,Cytosol No Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 30: White matter - Myelination" "Cluster 58: Non-specific - Nuclear processes" "Cluster 102: Non-specific - Mixed function" 9 Cytosol Nucleoli "HPA040830: , HPA066481: " "unprognostic (4.83e-2)" "unprognostic (1.48e-1)" "unprognostic (3.77e-2)" "unprognostic (4.01e-1)" "unprognostic (6.27e-2)" "unprognostic (4.11e-1)" "unprognostic (2.11e-1)" "unprognostic (1.56e-2)" "unprognostic (1.40e-1)" "unprognostic (4.43e-3)" "unprognostic (1.03e-2)" "potential prognostic unfavorable (2.28e-5)" "unprognostic (3.96e-3)" "potential prognostic unfavorable (1.58e-5)" "potential prognostic unfavorable (3.56e-5)" "unprognostic (1.98e-3)" "unprognostic (3.46e-2)" "unprognostic (1.03e-1)" "unprognostic (1.25e-1)" "unprognostic (7.12e-2)" "potential prognostic unfavorable (1.46e-4)" "unprognostic (4.73e-3)" "unprognostic (5.09e-2)" "unprognostic (8.58e-3)" "unprognostic (4.70e-2)" "unprognostic (1.68e-1)" "unprognostic (1.60e-1)" "unprognostic (6.13e-2)" "unprognostic (1.48e-2)" "unprognostic (1.57e-2)" ARHGAP11A-SCG5 ENSG00000288864 "ARHGAP11A-SCG5 readthrough" 15 32613860-32697095 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "HPA013136, HPA074618" Uncertain NA NA "Cluster 60: Stomach - Digestion" "Cluster 6: Non-specific - Immune response" "Cluster 72: Neuronal - Signal transduction" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "HPA013136: , HPA074618: " ARHGAP11B "B'-T, FAM7B1" ENSG00000285077 "Rho GTPase activating protein 11B" Q3KRB8 15 30624494-30649529 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.7" "Cell type enhanced" "Detected in some" "Enteric transient amplifying cells: 3.6;Extravillous trophoblasts: 1.5;Foveolar cells: 1.1;Gastric chief cells: 1.1;Kupffer cells: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Mitotic cells (Adrenal gland), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" HPA064479 Uncertain NA NA "Cluster 44: Bone marrow - Nuclear processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 58: Non-specific - Nuclear processes" "Cluster 27: Non-specific - Cell proliferation" "HPA064479: " "unprognostic (4.37e-2)" "unprognostic (2.28e-1)" "unprognostic (5.24e-2)" ARHGAP12 "FLJ10971, FLJ20737, FLJ21785" ENSG00000165322 "Rho GTPase activating protein 12" Q8IWW6 10 31805398-31928876 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Foveolar cells: 378.3;Microglia: 468.8" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 556.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000412 Enhanced NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 60: Stomach - Digestion" "Cluster 30: White matter - Myelination" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 11 "HPA000412: " "unprognostic (2.87e-2)" "unprognostic (1.11e-2)" "unprognostic (2.60e-1)" "unprognostic (1.78e-1)" "unprognostic (4.13e-2)" "unprognostic (1.01e-2)" "unprognostic (1.03e-2)" "potential prognostic favorable (6.08e-5)" "unprognostic (9.77e-2)" "potential prognostic unfavorable (5.34e-4)" "potential prognostic favorable (2.23e-7)" "unprognostic (1.39e-2)" "unprognostic (1.69e-2)" "unprognostic (6.62e-2)" "unprognostic (1.43e-1)" "unprognostic (6.51e-2)" "unprognostic (2.75e-1)" "unprognostic (8.65e-2)" "unprognostic (1.04e-1)" "unprognostic (1.05e-2)" "unprognostic (6.70e-3)" "potential prognostic unfavorable (5.12e-4)" "unprognostic (1.83e-1)" "unprognostic (1.54e-1)" "unprognostic (1.07e-2)" "unprognostic (7.68e-3)" "unprognostic (1.69e-1)" "unprognostic (2.07e-1)" "unprognostic (2.26e-1)" "unprognostic (1.65e-1)" "unprognostic (8.54e-2)" ARHGAP15 BM046 ENSG00000075884 "Rho GTPase activating protein 15" Q53QZ3 2 143091362-143768352 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "bone marrow: 75.1;lymphoid tissue: 70.0" "Group enriched" "Detected in many" 4 "Neutrophil progenitors: 5134.5;Neutrophils: 10528.3" "Group enriched" "Detected in all" 4 "central nervous system macrophage: 1510.9;leukocyte: 2114.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Leukemia: 69.1;lymphoma: 63.6" "Adipose visceral - T-cells, Breast - T-cells, Colon - Enteric glia cells, Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032126 Supported "Plasma membrane" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 24: Neutrophils - Innate immunity signal integration" 2 "Plasma membrane" "HPA032126: " "unprognostic (1.12e-1)" "unprognostic (1.29e-2)" "unprognostic (7.65e-3)" "potential prognostic favorable (4.24e-4)" "unprognostic (5.04e-2)" "unprognostic (6.96e-2)" "unprognostic (2.58e-2)" "unprognostic (2.05e-1)" "unprognostic (1.33e-2)" "unprognostic (1.40e-1)" "unprognostic (2.53e-2)" "unprognostic (8.00e-2)" "unprognostic (7.28e-2)" "unprognostic (1.08e-1)" "unprognostic (2.21e-2)" "potential prognostic favorable (2.69e-5)" "unprognostic (1.28e-1)" "unprognostic (1.06e-1)" "unprognostic (3.79e-1)" "unprognostic (7.77e-2)" "unprognostic (2.99e-1)" "unprognostic (1.62e-1)" "unprognostic (6.34e-2)" "unprognostic (1.81e-1)" "unprognostic (3.19e-1)" "unprognostic (8.43e-3)" "unprognostic (2.45e-1)" "unprognostic (3.26e-2)" "unprognostic (1.43e-2)" "unprognostic (1.65e-1)" "unprognostic (4.48e-3)" ARHGAP17 "FLJ10308, FLJ13219, NADRIN, RICH1, WBP15" ENSG00000140750 "Rho GTPase activating protein 17" Q68EM7 16 24919389-25015666 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 47.8;Bergmann glia: 47.4;Brain excitatory neurons: 45.9;Choroid plexus epithelial cells: 81.7;Distal convoluted tubule cells: 62.1;Loop of henle epithelial cells: 49.6;Microglia: 214.0;Oligodendrocyte progenitor cells: 68.7;Oligodendrocytes: 97.2;Podocytes: 74.3;Proximal tubule cells: 73.8;Renal collecting duct intercalated cells: 70.6;Renal collecting duct principal cells: 49.2;Renal connecting tubule cells: 94.5;Vascular smooth muscle cells: 55.3" "Cell type enhanced" "Detected in all" "vascular associated smooth muscle cell: 355.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Colon - Endothelial cells, Minor Salivary Gland - Endothelial cells, Prostate - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041703, HPA075891" Approved Supported "Plasma membrane,Cytosol" NA NA 5100 "Cluster 23: B-cells - Immunoglobulins" "Cluster 5: Spleen - Immune response" "Cluster 30: White matter - Myelination" "Cluster 55: Lymphoma - Immune response" "Cluster 102: Non-specific - Mixed function" 30 "Plasma membrane, Cytosol" "HPA041703: , HPA075891: " "unprognostic (1.46e-1)" "unprognostic (2.63e-2)" "potential prognostic favorable (1.38e-5)" "unprognostic (2.40e-1)" "unprognostic (1.58e-1)" "unprognostic (1.33e-1)" "unprognostic (1.25e-1)" "unprognostic (9.62e-2)" "unprognostic (8.53e-2)" "unprognostic (4.87e-1)" "unprognostic (3.39e-3)" "unprognostic (3.06e-3)" "unprognostic (1.29e-1)" "potential prognostic unfavorable (6.83e-6)" "unprognostic (8.69e-2)" "unprognostic (8.86e-2)" "unprognostic (3.26e-3)" "unprognostic (4.69e-2)" "unprognostic (3.40e-1)" "unprognostic (9.76e-2)" "unprognostic (5.59e-3)" "unprognostic (2.57e-2)" "potential prognostic unfavorable (5.66e-5)" "unprognostic (2.24e-1)" "unprognostic (1.99e-1)" "unprognostic (1.22e-1)" "unprognostic (1.56e-1)" "unprognostic (9.36e-2)" "unprognostic (3.48e-2)" "unprognostic (3.98e-2)" "unprognostic (9.04e-2)" ARHGAP18 "bA307O14.2, MacGAP" ENSG00000146376 "Rho GTPase activating protein 18" Q8N392 6 129576132-129710177 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 799.4;Fallopian tube ciliated cells: 525.2;Mast cells: 944.3;Megakaryocytes: 544.0;Platelets: 1275.8;Renal collecting duct intercalated cells: 1215.8;Respiratory ciliated cells: 546.5;Respiratory ionocytes: 769.6" "Cell type enhanced" "Detected in many" "eccentric medium spiny neuron: 297.7;ependymal cell: 314.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031595 Approved Supported "Nuclear speckles,Plasma membrane,Cytosol" NA NA 1300000 "Cluster 41: Basophils - Unknown function" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 49: HMC-1 - Innate immune response" "Cluster 58: Mast cells - Allergic inflammatory responses" 4 Cytosol "Nuclear speckles, Plasma membrane" "HPA031595: " "unprognostic (1.47e-1)" "unprognostic (6.93e-2)" "unprognostic (2.56e-1)" "unprognostic (2.73e-2)" "unprognostic (1.89e-1)" "unprognostic (9.40e-2)" "unprognostic (2.44e-1)" "unprognostic (7.12e-2)" "unprognostic (9.16e-2)" "unprognostic (4.51e-3)" "potential prognostic favorable (1.38e-7)" "unprognostic (9.80e-3)" "unprognostic (1.52e-1)" "potential prognostic unfavorable (7.49e-4)" "unprognostic (4.19e-1)" "unprognostic (6.58e-3)" "unprognostic (4.65e-3)" "unprognostic (1.79e-2)" "unprognostic (1.65e-3)" "unprognostic (6.94e-2)" "unprognostic (3.94e-3)" "validated prognostic unfavorable (3.69e-4)" "validated prognostic unfavorable (3.65e-4)" "unprognostic (2.33e-1)" "unprognostic (2.11e-3)" "unprognostic (9.15e-2)" "unprognostic (1.93e-1)" "unprognostic (1.93e-1)" "unprognostic (6.49e-2)" "unprognostic (5.94e-2)" "unprognostic (2.09e-2)" ARHGAP19 "FLJ00194, MGC14258" ENSG00000213390 "Rho GTPase activating protein 19" Q14CB8 10 97222173-97292673 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 19.9" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 1.4;Early primary spermatocytes: 2.1;Early spermatids: 3.0;Erythrocyte progenitors: 3.6;Erythrocytes: 3.0;Late primary spermatocytes: 1.3;Late spermatids: 2.8;Monocyte progenitors: 2.8;Neutrophil progenitors: 1.5;Oocytes: 4.6;Platelets: 1.4;Schwann cells: 1.7" "Cell type enhanced" "Detected in single" "upper rhombic lip: 1.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Colon - Enteric glia cells, Pancreas - Endothelial cells, Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035777, HPA043231" Uncertain Enhanced "Plasma membrane" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 10 "Plasma membrane" "HPA035777: , HPA043231: " "unprognostic (1.68e-2)" "unprognostic (4.45e-1)" "unprognostic (5.90e-2)" "unprognostic (1.85e-1)" "unprognostic (3.81e-1)" "unprognostic (3.41e-2)" "unprognostic (8.53e-2)" "unprognostic (1.69e-1)" "unprognostic (1.34e-2)" "potential prognostic favorable (1.60e-5)" "unprognostic (2.70e-3)" "unprognostic (1.40e-1)" "unprognostic (1.45e-1)" "unprognostic (2.40e-1)" "unprognostic (7.72e-3)" "unprognostic (3.08e-1)" "unprognostic (2.95e-2)" "unprognostic (2.24e-2)" "unprognostic (3.43e-2)" "unprognostic (2.50e-2)" "potential prognostic unfavorable (1.63e-4)" "unprognostic (2.43e-1)" "unprognostic (1.83e-2)" "unprognostic (1.32e-2)" "unprognostic (3.12e-1)" "unprognostic (7.96e-2)" "unprognostic (1.83e-1)" "unprognostic (1.69e-1)" "unprognostic (3.10e-2)" ARHGAP20 KIAA1391 ENSG00000137727 "Rho GTPase activating protein 20" Q9P2F6 11 110577042-110713189 "Disease related genes, Predicted intracellular proteins" "GTPase activation" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 279.2;Bergmann glia: 131.2;Brain excitatory neurons: 112.8;Brain inhibitory neurons: 162.1;Endometrial stromal cells: 211.5;Fibro-adipogenic progenitors: 192.1;Gonadotrophs: 116.0;Leydig cells: 204.4;Oligodendrocyte progenitor cells: 120.5;Peritubular myoid cells: 108.4;Retinal amacrine cells: 108.7;Sertoli cells: 233.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038458, HPA038459, HPA076303" Uncertain Approved Mitochondria NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" Mitochondria "HPA038458: , HPA038459: , HPA076303: " "unprognostic (5.38e-2)" "unprognostic (1.42e-1)" "unprognostic (1.78e-1)" "unprognostic (2.41e-1)" "unprognostic (3.15e-2)" "unprognostic (1.01e-1)" "unprognostic (8.19e-3)" "unprognostic (1.45e-1)" "unprognostic (1.49e-2)" "unprognostic (9.32e-2)" "unprognostic (2.86e-2)" "unprognostic (3.78e-2)" "potential prognostic unfavorable (7.14e-4)" ARHGAP21 "ARHGAP10, KIAA1424" ENSG00000107863 "Rho GTPase activating protein 21" Q5T5U3 10 24583609-24723887 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 74.7" "Cell type enhanced" "Detected in all" "Bergmann glia: 573.7;Oligodendrocytes: 1074.9;Platelets: 596.7" "Cell type enhanced" "Detected in all" "oligodendrocyte: 1542.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Spleen - Endothelial cells, Stomach - Gastric mucous cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036610, HPA057861" Approved Approved "Plasma membrane,Cell Junctions,Actin filaments" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 52: Non-specific - Mitochondria" "Cluster 80: Oligodendrocytes - Myelination" 24 "Plasma membrane, Cell Junctions" "Actin filaments" "HPA036610: , HPA057861: " "unprognostic (6.64e-2)" "unprognostic (4.08e-2)" "unprognostic (2.25e-1)" "unprognostic (1.02e-3)" "unprognostic (1.23e-1)" "unprognostic (3.94e-2)" "unprognostic (4.18e-1)" "potential prognostic favorable (2.73e-4)" "unprognostic (3.19e-2)" "unprognostic (1.65e-3)" "potential prognostic favorable (3.65e-7)" "unprognostic (1.98e-2)" "unprognostic (3.61e-1)" "unprognostic (1.28e-1)" "unprognostic (2.09e-1)" "unprognostic (2.14e-1)" "unprognostic (4.95e-2)" "unprognostic (5.02e-2)" "unprognostic (7.75e-2)" "unprognostic (4.01e-2)" "unprognostic (5.84e-2)" "potential prognostic unfavorable (2.68e-4)" "unprognostic (3.13e-2)" "unprognostic (1.49e-1)" "unprognostic (2.04e-2)" "unprognostic (7.50e-2)" "unprognostic (2.27e-1)" "unprognostic (1.33e-1)" "unprognostic (3.47e-1)" "unprognostic (1.62e-2)" "unprognostic (1.18e-1)" ARHGAP22 RhoGAP2 ENSG00000128805 "Rho GTPase activating protein 22" Q7Z5H3 10 48446036-48656265 "Predicted intracellular proteins" "Angiogenesis, Differentiation, Transcription, Transcription regulation" "Developmental protein, GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 36.7" "Cell type enriched" "Detected in many" 4 "Microglia: 1230.8" "Cell type enriched" "Detected in all" 4 "central nervous system macrophage: 1542.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "classical monocyte: 1.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Fibroblasts, Liver - Vascular endothelial cells, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020696, HPA040391, HPA064439" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 8 "Nucleoplasm, Cytosol" "Plasma membrane" "CAB020696: , HPA040391: , HPA064439: " "unprognostic (9.02e-2)" "unprognostic (1.42e-1)" "unprognostic (4.32e-2)" "unprognostic (4.50e-3)" "unprognostic (3.75e-2)" "unprognostic (2.30e-3)" "unprognostic (9.55e-2)" "potential prognostic favorable (6.69e-4)" "unprognostic (3.10e-2)" "unprognostic (2.35e-1)" "potential prognostic unfavorable (1.84e-4)" "unprognostic (3.00e-3)" "unprognostic (1.39e-1)" "unprognostic (2.55e-1)" "unprognostic (2.53e-1)" "unprognostic (1.24e-2)" "unprognostic (8.10e-2)" "unprognostic (9.17e-3)" "unprognostic (2.18e-1)" "unprognostic (2.12e-1)" "unprognostic (1.53e-1)" "unprognostic (1.02e-2)" "unprognostic (2.68e-1)" "unprognostic (3.16e-1)" "unprognostic (6.07e-3)" "unprognostic (4.01e-2)" "unprognostic (9.75e-2)" "unprognostic (3.21e-2)" "unprognostic (1.20e-1)" "unprognostic (4.16e-2)" ARHGAP23 KIAA1501 ENSG00000275832 "Rho GTPase activating protein 23" Q9P227 17 38419280-38512385 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 82.1" "Cell type enhanced" "Detected in some" "Astrocytes: 40.6;Bergmann glia: 26.0;Brain excitatory neurons: 19.0;Late spermatids: 18.7;Oligodendrocyte progenitor cells: 27.6;Oligodendrocytes: 171.6;Other brain neurons: 19.8;Papillary tip epithelial cells: 78.6;Podocytes: 87.5" "Cell type enhanced" "Detected in all" "oligodendrocyte: 218.7" "Cancer enhanced" "Detected in all" "Bladder Urothelial Carcinoma (TCGA): 61.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019818, HPA047291" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 68: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 80: Oligodendrocytes - Myelination" "Nucleoplasm, Plasma membrane" Cytosol "HPA019818: , HPA047291: " "unprognostic (2.20e-1)" "unprognostic (4.57e-1)" "unprognostic (2.32e-1)" "unprognostic (3.67e-1)" "unprognostic (8.19e-2)" "unprognostic (6.60e-2)" "unprognostic (5.06e-2)" "unprognostic (1.24e-1)" "unprognostic (4.14e-2)" "unprognostic (2.17e-2)" "unprognostic (4.45e-2)" "unprognostic (2.77e-2)" "unprognostic (1.17e-1)" "unprognostic (9.89e-3)" "unprognostic (2.64e-1)" "unprognostic (1.28e-1)" "unprognostic (8.36e-2)" "unprognostic (1.22e-1)" "potential prognostic unfavorable (6.70e-5)" "potential prognostic unfavorable (4.73e-5)" "unprognostic (1.10e-2)" "unprognostic (2.70e-1)" "unprognostic (6.82e-2)" "unprognostic (2.43e-1)" "unprognostic (3.52e-3)" "unprognostic (8.29e-2)" "unprognostic (1.79e-1)" "unprognostic (2.62e-2)" ARHGAP24 "DKFZP564B1162, FilGAP, FLJ33877" ENSG00000138639 "Rho GTPase activating protein 24" Q8N264 4 85475150-86002668 "Predicted intracellular proteins" "Angiogenesis, Differentiation" "Developmental protein, GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 93.2" "Cell type enhanced" "Detected in many" "B-cells: 1836.7;Fibro-adipogenic progenitors: 1120.1;Microglia: 4378.1;Neutrophil progenitors: 1961.1;Neutrophils: 1639.8;Syncytiotrophoblasts: 1428.6" "Cell type enriched" "Detected in all" 6 "central nervous system macrophage: 5568.0" "Cancer enhanced" "Detected in all" "Kidney Renal Papillary Cell Carcinoma (TCGA): 46.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 16.0;memory B-cell: 47.4;naive B-cell: 36.9;plasmacytoid DC: 12.7" "Group enriched" "Detected in many" 5 "B-cells: 47.4;dendritic cells: 12.7;monocytes: 16.0" "Low cancer specificity" "Detected in many" "Liver - Hepatic stellate cells, Prostate - Smooth muscle cells, Skeletal muscle - Fibroblasts, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014288 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 72: Kidney - Transmembrane transport" "Cluster 49: Hindbrain - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 13 "Plasma membrane, Cytosol" "HPA014288: " "unprognostic (2.25e-1)" "unprognostic (1.06e-1)" "unprognostic (1.48e-1)" "unprognostic (2.64e-2)" "unprognostic (3.96e-2)" "unprognostic (2.26e-1)" "unprognostic (1.24e-1)" "unprognostic (2.05e-2)" "unprognostic (1.71e-1)" "unprognostic (2.85e-1)" "validated prognostic favorable (2.79e-13)" "validated prognostic favorable (2.64e-4)" "potential prognostic favorable (8.25e-5)" "unprognostic (5.94e-3)" "unprognostic (3.82e-2)" "unprognostic (7.13e-2)" "unprognostic (2.08e-1)" "unprognostic (4.67e-2)" "unprognostic (8.25e-2)" "unprognostic (3.44e-2)" "unprognostic (2.44e-2)" "unprognostic (2.89e-1)" "unprognostic (1.05e-2)" "unprognostic (2.25e-1)" "unprognostic (1.81e-1)" "unprognostic (3.54e-2)" "unprognostic (2.68e-1)" "unprognostic (3.12e-2)" "unprognostic (4.52e-2)" "unprognostic (1.76e-2)" "unprognostic (2.04e-2)" ARHGAP25 KIAA0053 ENSG00000163219 "Rho GTPase activating protein 25" P42331 2 68679601-68826833 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 70.6" "Cell type enhanced" "Detected in many" "B-cells: 277.4;Hematopoietic stem cells: 180.0;Hofbauer cells: 190.1;Kupffer cells: 177.3;Macrophages: 147.6;Mast cells: 210.8;Microglia: 413.5;Neutrophil progenitors: 202.0;Neutrophils: 508.4;NK-cells: 143.0;T-cells: 178.7;Thymocytes: 303.2" "Group enriched" "Detected in many" 7 "central nervous system macrophage: 487.9;leukocyte: 290.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 659.6" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 25.5;lymphoma: 54.5" "Breast - T-cells, Prostate - T-cells, Spleen - B-cells (Spleen), Thyroid gland - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA035346, HPA061395" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 2 "Nucleoplasm, Vesicles" "HPA035346: , HPA061395: " "unprognostic (1.19e-1)" "unprognostic (4.46e-3)" "unprognostic (3.68e-2)" "unprognostic (6.71e-2)" "unprognostic (4.76e-2)" "unprognostic (2.49e-1)" "unprognostic (1.85e-1)" "unprognostic (1.82e-1)" "unprognostic (2.19e-2)" "unprognostic (6.10e-2)" "unprognostic (1.06e-2)" "unprognostic (3.24e-2)" "unprognostic (4.75e-2)" "unprognostic (2.00e-1)" "unprognostic (1.63e-2)" "potential prognostic favorable (2.96e-4)" "unprognostic (8.32e-2)" "unprognostic (6.33e-2)" "unprognostic (4.27e-1)" "unprognostic (1.26e-1)" "unprognostic (5.51e-2)" "unprognostic (1.65e-1)" "unprognostic (2.04e-2)" "unprognostic (1.62e-1)" "unprognostic (1.85e-1)" "unprognostic (2.90e-1)" "unprognostic (7.50e-2)" "unprognostic (3.16e-1)" "unprognostic (3.64e-2)" "unprognostic (1.53e-1)" "unprognostic (4.08e-1)" ARHGAP26 "GRAF, KIAA0621, OPHN1L, OPHN1L1" ENSG00000145819 "Rho GTPase activating protein 26" Q9UNA1 5 142770377-143229011 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Neutrophils: 7865.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "neutrophil: 24.8;NK-cell: 9.9" "Group enriched" "Detected in many" 4 "granulocytes: 24.8;NK-cells: 9.9" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Spleen - Neutrophils_2, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035106, HPA035107" Enhanced Approved Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 34: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 11 Cytosol "HPA035106: , HPA035107: " "unprognostic (8.23e-2)" "unprognostic (2.99e-2)" "unprognostic (1.06e-2)" "unprognostic (9.74e-3)" "unprognostic (1.22e-1)" "unprognostic (2.01e-1)" "unprognostic (1.35e-1)" "unprognostic (1.15e-2)" "unprognostic (1.84e-2)" "potential prognostic unfavorable (4.14e-4)" "validated prognostic favorable (4.39e-5)" "validated prognostic favorable (4.38e-5)" "unprognostic (1.76e-1)" "unprognostic (3.32e-3)" "unprognostic (1.57e-2)" "unprognostic (6.86e-3)" "unprognostic (5.09e-2)" "unprognostic (2.13e-1)" "unprognostic (8.41e-2)" "unprognostic (5.50e-2)" "unprognostic (2.72e-2)" "unprognostic (4.09e-3)" "unprognostic (2.77e-1)" "unprognostic (5.23e-2)" "unprognostic (4.42e-2)" "unprognostic (2.07e-2)" "unprognostic (1.11e-1)" "unprognostic (2.49e-1)" "unprognostic (1.83e-1)" "unprognostic (1.14e-2)" "unprognostic (4.85e-2)" ARHGAP27 "CAMGAP1, FLJ43547, SH3D20, SH3P20" ENSG00000159314 "Rho GTPase activating protein 27" Q6ZUM4 17 45393902-45434421 "Predicted intracellular proteins" Endocytosis "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 87.9" "Cell type enhanced" "Detected in some" "Brain inhibitory neurons: 13.2;Loop of henle epithelial cells: 14.2;Microglia: 77.8;Papillary tip epithelial cells: 37.8;Proximal tubule cells: 32.8;Renal collecting duct intercalated cells: 21.9;Renal collecting duct principal cells: 16.4;Renal connecting tubule cells: 15.8;Tuft cells: 11.5" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 94.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Minor salivary gland basal cells, Spleen - Neutrophils_2, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023919, HPA053053" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 102: Non-specific - Mixed function" 2 "Nucleoplasm, Cytosol" "HPA023919: , HPA053053: " "unprognostic (1.45e-1)" "unprognostic (2.21e-2)" "unprognostic (1.92e-3)" "unprognostic (2.01e-1)" "potential prognostic favorable (3.33e-4)" "unprognostic (1.25e-1)" "unprognostic (2.16e-2)" "unprognostic (9.22e-3)" "unprognostic (2.07e-1)" "unprognostic (3.61e-1)" "unprognostic (5.98e-2)" "unprognostic (3.01e-1)" "unprognostic (6.81e-2)" "unprognostic (1.71e-2)" "unprognostic (9.30e-2)" "unprognostic (3.47e-2)" "unprognostic (2.36e-2)" "unprognostic (2.91e-2)" "unprognostic (2.45e-1)" "unprognostic (1.70e-1)" "unprognostic (3.21e-1)" "unprognostic (1.29e-2)" "unprognostic (9.71e-2)" "unprognostic (4.23e-2)" "unprognostic (2.27e-1)" "unprognostic (1.58e-2)" "unprognostic (1.67e-2)" "unprognostic (1.07e-1)" "unprognostic (1.15e-1)" "unprognostic (9.22e-2)" "unprognostic (6.15e-2)" ARHGAP28 "FLJ10312, KIAA1314" ENSG00000088756 "Rho GTPase activating protein 28" Q9P2N2 18 6729716-6915716 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "placenta: 24.3;testis: 72.3" "Cell type enhanced" "Detected in many" "Early spermatids: 622.9;Late primary spermatocytes: 254.5;Late spermatids: 704.2;Mesothelial cells: 233.5;Myonuclei: 134.7;Podocytes: 1005.6;Prostatic glandular cells: 138.6" "Cell type enhanced" "Detected in many" "fibroblast: 117.6" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 14.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "neutrophil: 2.9" "Lineage enriched" "Detected in single" 12 "granulocytes: 2.9" "Cancer enhanced" "Detected in many" "Rhabdoid: 32.3;testis cancer: 20.8" "Kidney - Podocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA030413, HPA030414, HPA030415" Enhanced Approved "Nucleoplasm,Cell Junctions" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 9: Non-specific - Receptor signaling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 46: Skeletal myocytes - Muscle structure & formation" "Nucleoplasm, Cell Junctions" "HPA030413: , HPA030414: , HPA030415: " "unprognostic (3.25e-1)" "unprognostic (2.56e-1)" "unprognostic (1.69e-1)" "unprognostic (3.02e-2)" "unprognostic (5.15e-2)" "unprognostic (2.49e-1)" "unprognostic (2.47e-2)" "unprognostic (1.23e-1)" "potential prognostic unfavorable (9.57e-4)" "validated prognostic favorable (2.08e-7)" "validated prognostic favorable (2.16e-4)" "unprognostic (1.70e-1)" "unprognostic (2.96e-2)" "unprognostic (5.69e-2)" "unprognostic (1.54e-2)" "unprognostic (1.30e-1)" "unprognostic (9.12e-3)" "potential prognostic unfavorable (9.24e-4)" "unprognostic (5.04e-3)" "unprognostic (2.69e-1)" "unprognostic (3.21e-1)" "potential prognostic favorable (5.94e-4)" "unprognostic (5.38e-3)" "unprognostic (1.58e-3)" "unprognostic (5.79e-2)" "unprognostic (2.42e-2)" "unprognostic (2.88e-1)" ARHGAP29 PARG1 ENSG00000137962 "Rho GTPase activating protein 29" Q52LW3 1 94148988-94275068 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast secretory cells: 307.8;Loop of henle epithelial cells: 487.9;Lymphatic endothelial cells: 589.9;Podocytes: 400.6;Renal connecting tubule cells: 414.5;Vascular endothelial cells: 544.4" "Cell type enhanced" "Detected in many" "endothelial cell: 847.4;fibroblast: 1091.2;pericyte: 1467.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.1" "Lineage enriched" "Detected in single" 12 "monocytes: 1.1" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adrenal gland - Endothelial cells, Colon - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Spleen - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026534 Approved Approved "Nucleoplasm,Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 15: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 4 "Nucleoplasm, Centrosome" "Plasma membrane, Cytosol" "HPA026534: " "unprognostic (7.13e-2)" "unprognostic (7.40e-2)" "unprognostic (2.31e-1)" "unprognostic (1.74e-3)" "unprognostic (1.87e-1)" "unprognostic (6.49e-2)" "unprognostic (1.58e-2)" "unprognostic (9.07e-3)" "unprognostic (2.56e-2)" "unprognostic (4.56e-3)" "potential prognostic favorable (7.80e-5)" "unprognostic (6.95e-3)" "unprognostic (2.58e-2)" "unprognostic (5.51e-2)" "unprognostic (3.59e-2)" "unprognostic (2.51e-1)" "unprognostic (2.59e-2)" "unprognostic (1.15e-1)" "unprognostic (3.18e-1)" "unprognostic (6.73e-3)" "unprognostic (1.24e-1)" "unprognostic (2.65e-3)" "potential prognostic unfavorable (1.34e-4)" "unprognostic (3.74e-1)" "unprognostic (1.80e-1)" "unprognostic (4.16e-1)" "unprognostic (1.44e-1)" "unprognostic (8.58e-3)" "unprognostic (2.97e-1)" "unprognostic (1.45e-1)" "unprognostic (5.04e-3)" ARHGAP30 FLJ00267 ENSG00000186517 "Rho GTPase activating protein 30" Q7Z6I6 1 161046946-161069970 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 54.4;lymphoid tissue: 72.7" "Cell type enhanced" "Detected in many" "B-cells: 91.2;cDC: 99.2;Esophageal apical cells: 91.4;Macrophages: 80.7;Monocyte progenitors: 127.0;monocytes: 141.0;Neutrophil progenitors: 245.8;Neutrophils: 462.0;NK-cells: 129.5;Suprabasal keratinocytes: 81.1;T-cells: 103.9" "Group enriched" "Detected in some" 25 "central nervous system macrophage: 54.4;leukocyte: 136.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 32 "Leukemia: 75.1;lymphoma: 98.5;Myeloma: 129.5" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Liver - Kupffer cells, Prostate - T-cells, Skeletal muscle - Macrophages, Testis - Spermatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA036300 Uncertain Supported Vesicles NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 2 Vesicles "HPA036300: " "unprognostic (2.08e-2)" "unprognostic (1.84e-1)" "unprognostic (6.48e-3)" "unprognostic (3.22e-2)" "unprognostic (2.39e-1)" "unprognostic (2.19e-1)" "unprognostic (7.09e-2)" "unprognostic (1.40e-1)" "unprognostic (1.71e-3)" "unprognostic (8.52e-2)" "unprognostic (1.44e-1)" "unprognostic (1.28e-1)" "unprognostic (2.08e-1)" "unprognostic (4.40e-1)" "unprognostic (4.33e-2)" "potential prognostic favorable (3.61e-4)" "unprognostic (7.19e-3)" "unprognostic (3.04e-1)" "unprognostic (2.87e-1)" "unprognostic (1.01e-1)" "unprognostic (7.34e-2)" "unprognostic (1.13e-1)" "unprognostic (7.42e-2)" "unprognostic (2.31e-1)" "unprognostic (1.41e-2)" "unprognostic (2.65e-1)" "unprognostic (9.32e-3)" "unprognostic (1.87e-1)" "unprognostic (4.39e-2)" "unprognostic (4.79e-2)" "unprognostic (6.78e-2)" ARHGAP31 CDGAP ENSG00000031081 "Rho GTPase activating protein 31" Q2M1Z3 3 119294383-119420714 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 208.3;Bergmann glia: 585.0;Cardiomyocytes: 158.4;cDC: 283.3;Lymphatic endothelial cells: 190.9;Macrophages: 161.9;Microglia: 258.6;Oligodendrocyte progenitor cells: 296.1;Vascular endothelial cells: 397.9" "Cell type enhanced" "Detected in many" "Bergmann glia: 573.8;endothelial cell: 559.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 6.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adrenal gland - Endothelial cells, Breast - Endothelial cells, Minor Salivary Gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036380 Approved NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 19: Astrocytes - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 5 "HPA036380: " "unprognostic (4.67e-2)" "unprognostic (1.50e-1)" "unprognostic (3.33e-2)" "unprognostic (1.15e-1)" "unprognostic (1.21e-1)" "unprognostic (1.49e-1)" "unprognostic (6.13e-3)" "unprognostic (3.51e-1)" "unprognostic (3.58e-2)" "unprognostic (1.05e-1)" "validated prognostic favorable (1.17e-8)" "validated prognostic favorable (1.36e-4)" "unprognostic (3.03e-2)" "unprognostic (1.39e-2)" "unprognostic (4.82e-2)" "unprognostic (5.42e-2)" "unprognostic (6.26e-2)" "unprognostic (1.08e-1)" "unprognostic (1.50e-1)" "unprognostic (3.10e-3)" "unprognostic (4.67e-2)" "unprognostic (1.38e-1)" "unprognostic (2.26e-1)" "unprognostic (1.31e-1)" "unprognostic (1.30e-1)" "unprognostic (2.15e-1)" "unprognostic (1.24e-1)" "unprognostic (3.80e-2)" "unprognostic (1.06e-1)" "unprognostic (7.21e-2)" "unprognostic (5.66e-3)" ARHGAP32 "GC-GAP, GRIT, KIAA0712, MGC1892, RICS" ENSG00000134909 "Rho GTPase activating protein 32" A7KAX9 11 128965060-129279324 "Cancer-related genes, Predicted intracellular proteins" "GTPase activation" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Müller glia: 707.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038382, HPA038389, HPA061505" Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus,Cytosol" NA NA "Cluster 42: Retina - Visual perception" "Cluster 53: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" 51 "Golgi apparatus" "Nucleoplasm, Nucleoli fibrillar center, Cytosol" "HPA038382: , HPA038389: , HPA061505: " "unprognostic (1.04e-2)" "unprognostic (3.28e-2)" "unprognostic (1.08e-1)" "potential prognostic unfavorable (4.18e-4)" "unprognostic (3.69e-1)" "unprognostic (1.73e-1)" "unprognostic (4.01e-2)" "unprognostic (2.44e-3)" "unprognostic (6.08e-2)" "unprognostic (8.94e-2)" "potential prognostic favorable (5.22e-7)" "unprognostic (4.28e-3)" "unprognostic (1.26e-1)" "unprognostic (1.20e-1)" "unprognostic (7.69e-3)" "unprognostic (5.22e-2)" "unprognostic (1.58e-2)" "unprognostic (1.47e-1)" "unprognostic (3.70e-1)" "unprognostic (2.20e-1)" "unprognostic (1.31e-1)" "potential prognostic unfavorable (1.22e-4)" "unprognostic (6.60e-3)" "unprognostic (1.85e-1)" "unprognostic (2.43e-3)" "unprognostic (7.17e-2)" "unprognostic (4.59e-2)" "unprognostic (6.00e-2)" "unprognostic (2.75e-1)" "unprognostic (9.67e-3)" "unprognostic (2.17e-1)" ARHGAP33 "FLJ39019, SNX26, TCGAP" ENSG00000004777 "Rho GTPase activating protein 33" O14559 19 35774532-35788822 "Predicted intracellular proteins" "Protein transport, Transport" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 26.2;Early primary spermatocytes: 23.1;Oligodendrocyte progenitor cells: 28.4;Oligodendrocytes: 31.9;Other brain neurons: 24.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 28.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030117, HPA030118" Supported Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 67: Testis - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 27: Non-specific - Cell proliferation" 2 "Plasma membrane" "Actin filaments, Cytosol" "HPA030117: , HPA030118: " "unprognostic (2.03e-2)" "unprognostic (8.72e-3)" "unprognostic (8.40e-2)" "unprognostic (3.55e-1)" "unprognostic (3.88e-2)" "unprognostic (3.24e-1)" "unprognostic (2.52e-1)" "unprognostic (1.23e-1)" "unprognostic (3.07e-3)" "unprognostic (1.97e-2)" "potential prognostic unfavorable (5.41e-5)" "unprognostic (2.25e-1)" "unprognostic (2.64e-1)" "unprognostic (1.24e-3)" "unprognostic (3.35e-2)" "unprognostic (1.55e-1)" "unprognostic (1.89e-1)" "unprognostic (7.26e-2)" "unprognostic (2.80e-3)" "unprognostic (1.32e-2)" "unprognostic (3.02e-2)" "unprognostic (1.09e-3)" "unprognostic (6.10e-3)" "unprognostic (2.74e-2)" "unprognostic (1.79e-1)" "unprognostic (1.70e-1)" "unprognostic (1.02e-2)" "unprognostic (1.47e-1)" "unprognostic (3.24e-1)" "unprognostic (8.24e-2)" "unprognostic (1.78e-2)" ARHGAP35 "GRF-1, GRLF1, KIAA1722, P190A, p190ARhoGAP, p190RhoGAP" ENSG00000160007 "Rho GTPase activating protein 35" Q9NRY4 19 46860997-47005077 "Cancer-related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, GTPase activation, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Late spermatids: 1189.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037311, HPA055184, HPA056470" Approved Approved "Nuclear bodies,Microtubules,Aggresome" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 12 "Nuclear bodies" "Microtubules, Aggresome" "CAB037311: , HPA055184: , HPA056470: " "unprognostic (3.73e-2)" "unprognostic (1.63e-2)" "unprognostic (1.29e-3)" "unprognostic (1.69e-2)" "unprognostic (4.89e-2)" "unprognostic (5.11e-3)" "unprognostic (1.54e-1)" "unprognostic (3.90e-2)" "unprognostic (4.69e-1)" "validated prognostic favorable (8.75e-9)" "validated prognostic favorable (9.71e-4)" "unprognostic (3.04e-2)" "unprognostic (5.91e-3)" "unprognostic (1.97e-1)" "unprognostic (8.54e-2)" "unprognostic (2.53e-1)" "unprognostic (1.13e-1)" "unprognostic (2.93e-2)" "unprognostic (2.98e-2)" "unprognostic (3.29e-2)" "unprognostic (5.18e-2)" "unprognostic (3.09e-1)" "unprognostic (2.88e-1)" "unprognostic (1.36e-2)" "unprognostic (1.70e-1)" "unprognostic (1.13e-1)" "unprognostic (2.72e-1)" "unprognostic (2.21e-1)" "unprognostic (1.47e-1)" "unprognostic (1.47e-1)" ARHGAP36 FLJ30058 ENSG00000147256 "Rho GTPase activating protein 36" Q6ZRI8 X 131058346-131089885 "Predicted intracellular proteins" "GTPase activation" Hypotrichosis "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 18 "adrenal gland: 99.5;brain: 77.0;pituitary gland: 166.5" "Group enriched" "Detected in some" 18 "Adrenal medulla cells: 138.3;Lactotrophs: 150.5;Other brain neurons: 38.0;Somatotrophs: 41.7;Thymic myoid cells: 68.0;Thyrotrophs: 106.1" "Cell type enhanced" "Detected in some" "amygdala excitatory: 8.3;splatter: 9.9" "Cancer enriched" "Detected in some" 18 "Thyroid Carcinoma (TCGA): 113.7" "Region enhanced" "Detected in all" "hypothalamus: 284.2;pons: 310.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 12 "Neuroblastoma: 37.1" "Adrenal gland - Adrenal medulla cells, Pituitary gland - Lactotropes, Testis - Spermatogonia" "Region enhanced" "Detected in many" "hypothalamus: 89.4" "Low region specificity" "Detected in many" "HPA002064, HPA076209" Enhanced Approved "Nucleoplasm,Vesicles,Plasma membrane" Yes NA "Cluster 20: Pituitary gland - Hormone signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 3 Nucleoplasm "Vesicles, Plasma membrane" "HPA002064: , HPA076209: " "unprognostic (1.16e-2)" "unprognostic (1.76e-1)" "unprognostic (5.02e-2)" "potential prognostic favorable (5.40e-4)" "unprognostic (2.38e-1)" ARHGAP39 "CrGAP, KIAA1688, Vilse" ENSG00000147799 "Rho GTPase activating protein 39" Q9C0H5 8 144529179-144685846 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.1;testis: 20.3" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 130.6;Ependymal cells: 107.3;Epididymal efferent duct ciliated cells: 74.7;Fallopian tube ciliated cells: 85.7;Respiratory ciliated cells: 134.8;Schwann cells: 81.8;Thyrotrophs: 69.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Colon - Enteric glia cells, Lung - Respiratory ciliated cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024687 Approved Nucleoplasm NA NA "Cluster 67: Testis - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 34: Ciliated cells - Cilia assembly & function" 5 Nucleoplasm "HPA024687: " "unprognostic (3.61e-2)" "unprognostic (2.17e-2)" "unprognostic (1.18e-1)" "unprognostic (1.88e-2)" "unprognostic (2.81e-1)" "unprognostic (3.25e-1)" "unprognostic (3.43e-1)" "unprognostic (3.87e-2)" "unprognostic (4.05e-1)" "unprognostic (7.23e-3)" "unprognostic (4.89e-2)" "unprognostic (1.44e-1)" "unprognostic (1.05e-2)" "potential prognostic unfavorable (3.55e-8)" "unprognostic (2.80e-3)" "unprognostic (9.28e-2)" "unprognostic (1.48e-1)" "unprognostic (1.53e-2)" "unprognostic (1.03e-1)" "unprognostic (2.34e-1)" "unprognostic (4.55e-2)" "unprognostic (6.63e-3)" "unprognostic (4.89e-2)" "unprognostic (2.99e-1)" "unprognostic (5.42e-2)" "unprognostic (2.52e-2)" "unprognostic (3.28e-1)" "unprognostic (1.25e-1)" "unprognostic (2.98e-1)" "unprognostic (4.63e-2)" "unprognostic (1.22e-1)" ARHGAP4 "C1, KIAA0131, p115, RhoGAP4, SrGAP4" ENSG00000089820 "Rho GTPase activating protein 4" P98171 X 153907367-153934999 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 106.5;lymphoid tissue: 114.4" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 31.9;B-cells: 39.2;cDC: 28.7;Hematopoietic stem cells: 32.5;Hofbauer cells: 28.3;Kupffer cells: 27.7;Macrophages: 34.0;Microglia: 30.2;Monocyte progenitors: 28.6;Neutrophil progenitors: 54.3;Neutrophils: 60.7;NK-cells: 28.1;pDCs: 35.5;T-cells: 27.7;Thymocytes: 43.2;Tuft cells: 92.2" "Group enriched" "Detected in many" 5 "central nervous system macrophage: 38.5;choroid plexus epithelial cell: 20.8;leukocyte: 31.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 90.9;Myeloma: 97.2" "Skeletal muscle - Macrophages, Thyroid gland - T-cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA000301, HPA001012, HPA001083" Enhanced Supported Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 2 Cytosol "HPA000301: , HPA001012: , HPA001083: " "unprognostic (2.68e-1)" "unprognostic (1.88e-2)" "unprognostic (2.19e-1)" "unprognostic (7.73e-2)" "potential prognostic unfavorable (1.34e-4)" "unprognostic (3.85e-2)" "unprognostic (7.51e-2)" "unprognostic (3.90e-2)" "potential prognostic favorable (2.41e-5)" "unprognostic (4.98e-2)" "potential prognostic unfavorable (1.75e-4)" "unprognostic (2.79e-2)" "unprognostic (5.71e-3)" "potential prognostic unfavorable (4.35e-4)" "unprognostic (1.51e-1)" "unprognostic (4.32e-2)" "unprognostic (5.50e-2)" "unprognostic (2.74e-1)" "unprognostic (3.14e-1)" "unprognostic (2.30e-1)" "unprognostic (2.62e-1)" "unprognostic (2.05e-2)" "unprognostic (1.44e-2)" "unprognostic (2.88e-1)" "unprognostic (7.39e-2)" "unprognostic (1.27e-1)" "unprognostic (5.38e-2)" "unprognostic (2.74e-2)" "unprognostic (5.44e-2)" "unprognostic (1.35e-1)" "unprognostic (1.99e-1)" ARHGAP40 "C20orf95, dJ1100H13.4" ENSG00000124143 "Rho GTPase activating protein 40" Q5TG30 20 38601809-38651035 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 4 "breast: 28.5;epididymis: 33.6;esophagus: 25.1;skin 1: 42.4" "Cell type enhanced" "Detected in some" "Breast hormone-responsive cells: 38.0;Early spermatids: 20.9;Ependymal cells: 10.9;Epididymal principal cells: 15.7;Esophageal apical cells: 116.2;Late spermatids: 10.7;Papillary tip epithelial cells: 12.6;Prostatic glandular cells: 17.1;Urothelial cells: 16.7" "Cell type enhanced" "Detected in some" "ependymal cell: 11.7;medium spiny neuron: 3.6" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 14.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 11.8" "Breast - Breast glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "HPA042636, HPA042840" Uncertain Approved "Nucleoplasm,Plasma membrane,Centrosome,Cytosol" No NA "Cluster 58: Skin - Keratinization" "Cluster 33: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 84: Apical squamous epithelium - Cornification" "Plasma membrane, Cytosol" "Nucleoplasm, Centrosome" "HPA042636: , HPA042840: " "unprognostic (1.76e-1)" "unprognostic (2.19e-2)" "unprognostic (7.59e-2)" "unprognostic (2.14e-1)" "unprognostic (1.70e-1)" "unprognostic (1.18e-3)" "unprognostic (7.84e-2)" "unprognostic (3.05e-3)" "unprognostic (7.01e-2)" "unprognostic (1.18e-2)" "unprognostic (1.21e-2)" "unprognostic (1.14e-2)" "potential prognostic unfavorable (1.72e-6)" "unprognostic (6.05e-2)" "unprognostic (1.63e-1)" "unprognostic (1.23e-1)" "unprognostic (2.46e-1)" "unprognostic (1.01e-2)" ARHGAP42 "AD031, FLJ32810, GRAF3, TMEM133" ENSG00000165895 "Rho GTPase activating protein 42" A6NI28 11 100687288-100993941 "Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 29.2" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 384.1;Endometrial luminal cells: 365.4;Foveolar cells: 473.7;Pericytes: 450.1;Respiratory ciliated cells: 393.2;Rod photoreceptor cells: 583.2;Transitional alveolar cells: 447.6;Urothelial cells: 852.8" "Cell type enhanced" "Detected in many" "pericyte: 1081.0;vascular associated smooth muscle cell: 400.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adrenal gland - Fibroblasts, Spleen - Endothelial cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039924, HPA060528" Uncertain Approved "Nuclear speckles,Cytosol" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 42: Retina - Visual perception" "Cluster 39: Astrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 110: Mural cells - ECM organization" 1 "Nuclear speckles" Cytosol "HPA039924: , HPA060528: " "unprognostic (6.25e-2)" "unprognostic (1.47e-1)" "unprognostic (2.64e-1)" "unprognostic (1.52e-2)" "unprognostic (1.99e-1)" "unprognostic (4.14e-2)" "unprognostic (2.14e-2)" "unprognostic (4.18e-1)" "unprognostic (2.24e-1)" "unprognostic (4.20e-2)" "potential prognostic favorable (2.70e-5)" "unprognostic (3.62e-3)" "potential prognostic favorable (2.19e-5)" "unprognostic (3.63e-3)" "unprognostic (2.91e-1)" "unprognostic (1.13e-1)" "unprognostic (3.63e-3)" "unprognostic (1.51e-1)" "unprognostic (3.57e-1)" "unprognostic (3.65e-2)" "unprognostic (5.53e-2)" "potential prognostic unfavorable (1.20e-4)" "unprognostic (2.37e-2)" "unprognostic (2.18e-1)" "unprognostic (1.87e-2)" "unprognostic (5.94e-3)" "potential prognostic unfavorable (8.31e-4)" "unprognostic (1.45e-1)" "unprognostic (5.41e-1)" "unprognostic (1.71e-2)" "unprognostic (6.82e-3)" ARHGAP44 "KIAA0672, RICH-2, RICH2" ENSG00000006740 "Rho GTPase activating protein 44" Q17R89 17 12789498-12991643 "Predicted intracellular proteins" Exocytosis "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 278.7;Brain excitatory neurons: 322.9;Gonadotrophs: 286.1;Lactotrophs: 435.3;Mesothelial cells: 416.6;Other brain neurons: 273.6;Retinal amacrine cells: 441.7;Retinal horizontal cells: 1129.9;Somatotrophs: 273.5;Thyrotrophs: 553.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 11.2" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Adrenal gland - Fibroblasts, Lung - Alveolar cells type 1, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Lactotropes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038814 Approved NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 109: Neurons - Neuronal signaling" 15 "HPA038814: " "unprognostic (7.30e-2)" "unprognostic (1.61e-2)" "unprognostic (1.05e-1)" "unprognostic (1.75e-2)" "potential prognostic favorable (6.94e-5)" "unprognostic (1.95e-1)" "unprognostic (6.69e-2)" "unprognostic (1.31e-2)" "unprognostic (5.96e-2)" "unprognostic (2.12e-2)" "unprognostic (2.71e-1)" "unprognostic (1.62e-1)" "unprognostic (2.69e-3)" "unprognostic (2.01e-1)" "unprognostic (5.11e-3)" "unprognostic (5.52e-2)" "unprognostic (6.15e-2)" "unprognostic (3.90e-1)" "unprognostic (3.68e-2)" "unprognostic (1.56e-1)" "unprognostic (3.55e-2)" "unprognostic (1.77e-2)" "unprognostic (9.85e-2)" "unprognostic (1.58e-2)" "unprognostic (8.03e-2)" "unprognostic (1.28e-1)" "unprognostic (5.28e-2)" ARHGAP45 "HA-1, HMHA1, KIAA0223" ENSG00000180448 "Rho GTPase activating protein 45" Q92619 19 1065923-1086628 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 64.4;intestine: 49.3;lung: 37.7;lymphoid tissue: 100.9" "Cell type enhanced" "Detected in many" "B-cells: 85.9;Breast lactating cells: 83.3;Epicardial cells: 156.9;Extravillous trophoblasts: 81.0;Megakaryocytes: 105.1;Monocyte progenitors: 90.0;monocytes: 90.3;Neutrophils: 194.5;NK-cells: 93.1;Oocytes: 184.2;Platelets: 336.9;Syncytiotrophoblasts: 90.3;T-cells: 86.1" "Group enriched" "Detected in some" 65 "central nervous system macrophage: 70.6;leukocyte: 106.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Leukemia: 93.4;lymphoma: 73.9;Myeloma: 97.1" "Colon - T-cells, Heart muscle - Macrophages, Kidney - T-cells, Liver - T-cells, Prostate - T-cells, Skeletal muscle - Macrophages, Skin - T-cells, Thyroid gland - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA019816, HPA079252" Enhanced Supported "Plasma membrane,Cytosol" NA NA 610000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 8 "Plasma membrane, Cytosol" "HPA019816: , HPA079252: " "unprognostic (6.65e-3)" "unprognostic (1.81e-1)" "unprognostic (5.90e-2)" "unprognostic (1.63e-1)" "unprognostic (1.90e-2)" "unprognostic (1.10e-1)" "unprognostic (1.16e-1)" "potential prognostic favorable (3.35e-4)" "unprognostic (2.15e-1)" "unprognostic (6.89e-2)" "unprognostic (1.97e-1)" "unprognostic (8.88e-2)" "unprognostic (2.64e-2)" "unprognostic (4.99e-3)" "unprognostic (2.25e-1)" "unprognostic (2.36e-2)" "unprognostic (3.70e-1)" "unprognostic (3.15e-2)" "unprognostic (3.27e-2)" "unprognostic (2.25e-1)" "unprognostic (1.57e-2)" "unprognostic (2.56e-1)" "unprognostic (1.54e-1)" "unprognostic (2.64e-2)" "unprognostic (8.39e-2)" "unprognostic (3.97e-1)" "unprognostic (8.17e-3)" "unprognostic (9.92e-2)" "unprognostic (2.59e-1)" ARHGAP5 "GFI2, p190-B, p190BRhoGAP, RhoGAP5" ENSG00000100852 "Rho GTPase activating protein 5" Q13017 14 32076114-32159728 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 716.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Endothelial cells, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046993, HPA056507" Approved Supported "Endoplasmic reticulum,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 42: Retina - Visual perception" "Cluster 55: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 51: Secretory epithelial cells - Mixed function" 12 "Endoplasmic reticulum, Cytosol" "HPA046993: , HPA056507: " "unprognostic (3.20e-2)" "unprognostic (2.33e-1)" "unprognostic (2.11e-1)" "unprognostic (5.24e-2)" "unprognostic (1.81e-3)" "potential prognostic unfavorable (1.62e-4)" "unprognostic (2.32e-1)" "unprognostic (2.00e-1)" "unprognostic (1.05e-1)" "unprognostic (2.13e-1)" "validated prognostic favorable (5.73e-9)" "validated prognostic favorable (4.82e-4)" "unprognostic (5.67e-3)" "unprognostic (1.52e-3)" "unprognostic (1.38e-1)" "unprognostic (6.13e-2)" "unprognostic (4.93e-2)" "unprognostic (2.25e-2)" "unprognostic (1.80e-1)" "unprognostic (3.26e-3)" "potential prognostic unfavorable (1.77e-4)" "unprognostic (1.50e-2)" "unprognostic (1.31e-3)" "unprognostic (4.39e-2)" "unprognostic (1.07e-1)" "unprognostic (1.03e-1)" "unprognostic (2.38e-2)" "unprognostic (1.58e-2)" "unprognostic (2.15e-1)" "unprognostic (8.95e-2)" "unprognostic (1.21e-1)" ARHGAP6 rhoGAPX-1 ENSG00000047648 "Rho GTPase activating protein 6" O43182 X 11117651-11665920 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 2375.4;Loop of henle epithelial cells: 984.8;Mesothelial cells: 737.6;Pericytes: 544.2;Platelets: 543.3;Prostatic glandular cells: 1520.0;Proximal tubule cells: 789.2;Renal collecting duct intercalated cells: 519.9;Renal collecting duct principal cells: 571.2;Renal connecting tubule cells: 876.1" "Cell type enhanced" "Detected in all" "pericyte: 708.4;vascular associated smooth muscle cell: 592.5" "Group enriched" "Detected in many" 4 "Kidney Chromophobe (TCGA): 32.2;Prostate Adenocarcinoma (TCGA): 32.6;Thyroid Carcinoma (TCGA): 11.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "prostate cancer: 22.1" "Prostate - Prostate glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA001798, HPA002715, HPA036779, HPA064390" Enhanced Supported "Mitotic spindle,Cytosol" Yes NA 190000 "Cluster 75: Ovary - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 60: Prostate cancer - Unknown function" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" Cytosol "Mitotic spindle" "HPA001798: , HPA002715: , HPA036779: , HPA064390: " "unprognostic (5.69e-2)" "unprognostic (9.96e-2)" "unprognostic (1.59e-1)" "unprognostic (5.04e-2)" "unprognostic (6.14e-2)" "unprognostic (7.09e-3)" "unprognostic (2.37e-1)" "unprognostic (2.46e-1)" "validated prognostic favorable (7.27e-10)" "validated prognostic favorable (8.86e-4)" "unprognostic (1.03e-1)" "unprognostic (1.65e-2)" "unprognostic (6.74e-2)" "unprognostic (6.13e-2)" "unprognostic (6.22e-2)" "unprognostic (5.27e-3)" "unprognostic (1.95e-2)" "unprognostic (2.83e-1)" "unprognostic (1.62e-1)" "unprognostic (1.72e-1)" "unprognostic (4.73e-3)" "unprognostic (1.38e-2)" "unprognostic (9.74e-2)" "unprognostic (2.82e-2)" ARHGAP8 "BPGAP1, FLJ20185" ENSG00000241484 "Rho GTPase activating protein 8" P85298 22 44752558-44862788 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 23.2;salivary gland: 21.9" "Cell type enhanced" "Detected in many" "Astrocytes: 10.1;Bergmann glia: 12.7;Choroid plexus epithelial cells: 64.4;Enteric stem cells: 13.2;Enteric transient amplifying cells: 11.8;Epididymal efferent duct absorptive cells: 10.9;Epididymal principal cells: 9.8;Oocytes: 41.4;Paneth cells: 15.5" "Cell type enriched" "Detected in many" 6 "choroid plexus epithelial cell: 82.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Breast - Breast glandular cells, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA069694 Approved NA No "Cluster 60: Stomach - Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 1 "HPA069694: " "unprognostic (1.62e-2)" "unprognostic (1.20e-2)" "unprognostic (1.34e-2)" "unprognostic (8.14e-2)" "unprognostic (1.98e-1)" "unprognostic (3.30e-3)" "unprognostic (1.00e-3)" "unprognostic (4.43e-1)" "potential prognostic favorable (4.52e-8)" "unprognostic (3.19e-3)" "unprognostic (2.20e-1)" "unprognostic (2.40e-1)" "potential prognostic favorable (6.40e-5)" "unprognostic (1.73e-1)" "unprognostic (6.01e-1)" "unprognostic (2.23e-2)" "unprognostic (1.43e-2)" "unprognostic (2.67e-2)" "unprognostic (1.72e-1)" "potential prognostic unfavorable (5.00e-4)" "unprognostic (2.34e-2)" "unprognostic (1.06e-1)" "unprognostic (4.62e-3)" "unprognostic (5.98e-2)" "unprognostic (9.58e-2)" "unprognostic (8.39e-2)" "unprognostic (2.23e-1)" "unprognostic (5.81e-2)" "unprognostic (5.04e-1)" ARHGAP9 "10C, MGC1295" ENSG00000123329 "Rho GTPase activating protein 9" Q9BRR9 12 57472264-57488814 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 113.0;lymphoid tissue: 96.5" "Cell type enhanced" "Detected in many" "Early spermatids: 70.4;Hofbauer cells: 73.5;Innate lymphoid cells: 78.9;Late primary spermatocytes: 204.1;Late spermatids: 55.3;monocytes: 54.1;Neutrophil progenitors: 142.2;Neutrophils: 429.3;NK-cells: 147.3;pDCs: 107.1;T-cells: 76.9" "Group enriched" "Detected in many" 4 "central nervous system macrophage: 33.6;leukocyte: 57.5;lower rhombic lip: 15.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 392.7" "Lineage enriched" "Detected in all" 4 "granulocytes: 392.7" "Group enriched" "Detected in some" 7 "Leukemia: 36.2;lymphoma: 18.0;Myeloma: 13.8" "Adipose subcutaneous - Macrophages, Breast - T-cells, Kidney - T-cells, Lung - NK-cells (Lung), Pituitary gland - T-cells, Prostate - T-cells, Skin - T-cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - T-cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA078822 Approved "Plasma membrane,Cell Junctions" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 37: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 14 "Plasma membrane" "Cell Junctions" "HPA078822: " "unprognostic (8.17e-3)" "unprognostic (1.17e-2)" "unprognostic (8.05e-2)" "potential prognostic favorable (4.24e-4)" "unprognostic (1.76e-1)" "unprognostic (6.75e-2)" "unprognostic (6.77e-2)" "unprognostic (2.86e-1)" "potential prognostic favorable (4.36e-4)" "unprognostic (2.25e-1)" "unprognostic (5.60e-3)" "unprognostic (4.65e-1)" "unprognostic (2.59e-1)" "unprognostic (3.42e-1)" "unprognostic (2.53e-2)" "unprognostic (3.87e-3)" "unprognostic (1.97e-1)" "unprognostic (1.48e-1)" "unprognostic (1.13e-1)" "unprognostic (1.64e-1)" "unprognostic (5.32e-2)" "unprognostic (1.29e-1)" "unprognostic (5.24e-2)" "unprognostic (2.49e-1)" "unprognostic (1.92e-2)" "unprognostic (2.06e-1)" "unprognostic (1.66e-3)" "unprognostic (1.43e-1)" "unprognostic (3.56e-2)" "unprognostic (2.73e-2)" "unprognostic (2.28e-1)" ARHGDIA "GDIA1, RHOGDI" ENSG00000141522 "Rho GDP dissociation inhibitor alpha" P52565 17 81867721-81871378 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 363.9;Extravillous trophoblasts: 340.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010005, HPA021407" Approved Supported Cytosol NA NA 17000000 "Cluster 25: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 43 Cytosol "CAB010005: , HPA021407: " "unprognostic (1.61e-1)" "unprognostic (2.08e-1)" "unprognostic (8.14e-2)" "unprognostic (2.37e-3)" "unprognostic (4.13e-2)" "unprognostic (6.49e-2)" "unprognostic (6.78e-2)" "unprognostic (1.73e-1)" "unprognostic (1.09e-2)" "unprognostic (3.26e-3)" "unprognostic (8.44e-3)" "unprognostic (1.17e-1)" "unprognostic (3.59e-2)" "potential prognostic unfavorable (4.87e-4)" "unprognostic (2.55e-2)" "unprognostic (1.17e-2)" "unprognostic (5.38e-3)" "unprognostic (1.51e-2)" "unprognostic (1.35e-1)" "unprognostic (2.51e-1)" "unprognostic (3.75e-2)" "unprognostic (1.40e-1)" "unprognostic (5.84e-2)" "potential prognostic unfavorable (7.40e-4)" "unprognostic (1.50e-1)" "unprognostic (3.54e-1)" "unprognostic (2.38e-1)" "unprognostic (3.50e-1)" "unprognostic (1.91e-1)" "unprognostic (1.03e-1)" "unprognostic (3.03e-1)" ARHGDIB "GDIA2, GDID4, Ly-GDI, RAP1GN1, RhoGDI2" ENSG00000111348 "Rho GDP dissociation inhibitor beta" P52566 12 14942031-14961728 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "bone marrow: 1491.2;lymphoid tissue: 1001.9" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 1010.2;Hofbauer cells: 1168.4;Kupffer cells: 775.9;Mast cells: 850.9;Megakaryocyte progenitors: 604.4;Megakaryocytes: 1335.2;Monocyte progenitors: 708.7;monocytes: 625.7;Neutrophil progenitors: 912.1;Neutrophils: 1322.1;NK-cells: 536.7;Platelets: 1664.1;T-cells: 718.7" "Group enriched" "Detected in some" 5 "central nervous system macrophage: 129.1;leukocyte: 206.7;pericyte: 87.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 1348.1;lymphoma: 998.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018584, HPA051235" Enhanced Supported Cytosol NA NA 41000000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" 9 Cytosol "CAB018584: , HPA051235: " "unprognostic (4.53e-3)" "unprognostic (4.47e-3)" "unprognostic (1.72e-2)" "unprognostic (1.44e-1)" "unprognostic (7.78e-2)" "unprognostic (2.78e-1)" "unprognostic (1.15e-1)" "unprognostic (1.69e-1)" "unprognostic (5.83e-3)" "unprognostic (1.59e-1)" "unprognostic (5.56e-2)" "unprognostic (2.90e-2)" "unprognostic (4.93e-2)" "unprognostic (2.46e-1)" "unprognostic (1.36e-1)" "unprognostic (4.61e-2)" "unprognostic (3.92e-3)" "unprognostic (2.25e-1)" "unprognostic (1.11e-1)" "unprognostic (1.59e-1)" "unprognostic (6.15e-2)" "unprognostic (8.79e-3)" "unprognostic (7.40e-2)" "unprognostic (7.80e-2)" "unprognostic (1.69e-2)" "unprognostic (1.47e-1)" "unprognostic (2.47e-1)" "unprognostic (9.30e-2)" "unprognostic (3.31e-3)" "unprognostic (2.13e-1)" "unprognostic (3.85e-1)" ARHGDIG RHOGDI-3 ENSG00000242173 "Rho GDP dissociation inhibitor gamma" Q99819 16 280450-283010 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 245.6;pancreas: 105.9" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 48.9;Brain inhibitory neurons: 43.1;Enterocytes: 47.6;Gastric chief cells: 52.4;Mucous neck cells: 24.0;Other brain neurons: 92.0;Pancreatic acinar cells: 83.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 15.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 15.2" "Adrenal gland - Adrenal medulla cells, Breast - Adipocytes (Breast), Pituitary gland - Undifferentiated cells (Pituitary gland), Stomach - Chief cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078260 Approved "Plasma membrane,Cytosol" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 1: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 98: Neurons - Neurotransmission & signaling" 7 "Plasma membrane, Cytosol" "HPA078260: " "unprognostic (3.17e-3)" "unprognostic (1.88e-1)" "unprognostic (3.19e-2)" "unprognostic (2.14e-2)" "unprognostic (1.11e-1)" "unprognostic (6.06e-3)" "unprognostic (3.78e-3)" "unprognostic (4.03e-1)" "unprognostic (5.86e-2)" "unprognostic (3.87e-1)" "unprognostic (9.33e-2)" "unprognostic (3.89e-3)" "unprognostic (1.27e-2)" "unprognostic (3.10e-1)" "unprognostic (2.79e-1)" ARHGEF1 "LBCL2, P115-RHOGEF, SUB1.5" ENSG00000076928 "Rho guanine nucleotide exchange factor 1" Q92888 19 41883173-41930150 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 165.2" "Cell type enhanced" "Detected in many" "B-cells: 100.9;Neutrophils: 145.1;NK-cells: 165.3;T-cells: 141.9" "Cell type enhanced" "Detected in all" "leukocyte: 166.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - T-cells, Spleen - B-cells (Spleen), Testis - Endothelial cells, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009502, HPA012924, HPA060784" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 11: White matter - Signal transduction" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 13 "Plasma membrane, Cytosol" "CAB009502: , HPA012924: , HPA060784: " "unprognostic (1.07e-1)" "unprognostic (7.06e-3)" "unprognostic (1.08e-1)" "unprognostic (1.94e-1)" "unprognostic (9.82e-2)" "unprognostic (7.47e-3)" "unprognostic (1.26e-1)" "unprognostic (6.82e-2)" "unprognostic (3.19e-1)" "unprognostic (5.00e-2)" "unprognostic (6.02e-2)" "unprognostic (2.35e-1)" "unprognostic (9.76e-2)" "unprognostic (4.25e-2)" "unprognostic (3.79e-2)" "unprognostic (7.42e-2)" "unprognostic (9.91e-2)" "unprognostic (1.40e-1)" "unprognostic (9.47e-2)" "unprognostic (1.85e-2)" "unprognostic (2.08e-2)" "unprognostic (1.47e-1)" "unprognostic (1.43e-1)" "unprognostic (4.53e-2)" "unprognostic (3.08e-1)" "unprognostic (4.42e-3)" "unprognostic (2.10e-2)" "unprognostic (2.60e-1)" "unprognostic (1.76e-1)" "unprognostic (7.19e-2)" "unprognostic (4.24e-2)" ARHGEF10 "Gef10, KIAA0294" ENSG00000104728 "Rho guanine nucleotide exchange factor 10" O15013 8 1823926-1958641 "Disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 7 "Astrocytes: 147.7;Bergmann glia: 83.6;Choroid plexus epithelial cells: 138.0;Ependymal cells: 85.4;Oligodendrocyte progenitor cells: 106.1;Oligodendrocytes: 189.6" "Cell type enhanced" "Detected in all" "oligodendrocyte: 237.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024649 Approved Approved Nucleoplasm NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 104: Brain endothelial cells - Blood brain barrier" 7 Nucleoplasm "HPA024649: " "unprognostic (1.65e-2)" "unprognostic (2.97e-1)" "unprognostic (2.87e-2)" "unprognostic (2.04e-1)" "unprognostic (6.65e-2)" "unprognostic (3.36e-2)" "unprognostic (1.53e-1)" "unprognostic (1.29e-1)" "unprognostic (1.66e-1)" "unprognostic (1.14e-1)" "potential prognostic favorable (1.75e-4)" "unprognostic (1.07e-3)" "unprognostic (2.98e-1)" "unprognostic (1.36e-3)" "unprognostic (1.68e-1)" "unprognostic (3.84e-2)" "unprognostic (4.95e-3)" "unprognostic (1.72e-1)" "unprognostic (1.28e-1)" "unprognostic (9.27e-2)" "unprognostic (9.86e-2)" "unprognostic (1.78e-3)" "unprognostic (1.39e-1)" "unprognostic (7.71e-2)" "unprognostic (1.57e-2)" "unprognostic (5.83e-2)" "unprognostic (1.94e-2)" "unprognostic (4.27e-1)" "unprognostic (1.10e-1)" "unprognostic (7.53e-2)" ARHGEF10L "FLJ10521, KIAA1626" ENSG00000074964 "Rho guanine nucleotide exchange factor 10 like" Q9HCE6 1 17539698-17697874 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 434.4;Renal collecting duct principal cells: 236.6;Renal connecting tubule cells: 327.6;Tuft cells: 276.7" "Cell type enhanced" "Detected in all" "vascular associated smooth muscle cell: 270.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 41 "classical monocyte: 18.8;intermediate monocyte: 18.0;myeloid DC: 13.4;non-classical monocyte: 4.8" "Group enriched" "Detected in many" 48 "dendritic cells: 13.4;monocytes: 18.8" "Low cancer specificity" "Detected in many" "Prostate - Smooth muscle cells, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026426, HPA026440, HPA028115" Approved Approved "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 24: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 62: Smooth muscle cells - Muscle contraction" 1 "Golgi apparatus, Vesicles, Cytosol" "HPA026426: , HPA026440: , HPA028115: " "unprognostic (9.80e-2)" "unprognostic (7.98e-2)" "unprognostic (1.03e-1)" "unprognostic (6.67e-2)" "unprognostic (7.89e-2)" "unprognostic (3.67e-2)" "unprognostic (2.18e-2)" "potential prognostic favorable (1.70e-5)" "unprognostic (4.85e-3)" "unprognostic (3.04e-1)" "potential prognostic favorable (1.14e-7)" "unprognostic (2.00e-2)" "unprognostic (9.31e-3)" "unprognostic (6.20e-2)" "unprognostic (7.78e-3)" "unprognostic (1.04e-1)" "unprognostic (1.33e-1)" "unprognostic (1.58e-2)" "unprognostic (2.49e-1)" "unprognostic (5.06e-2)" "unprognostic (2.13e-1)" "unprognostic (3.68e-2)" "unprognostic (1.54e-1)" "unprognostic (1.34e-1)" "unprognostic (1.30e-1)" "unprognostic (2.97e-2)" "unprognostic (4.03e-2)" "unprognostic (3.52e-2)" "unprognostic (1.56e-1)" "unprognostic (4.36e-2)" "unprognostic (2.92e-1)" ARHGEF11 "GTRAP48, KIAA0380, PDZ-RHOGEF" ENSG00000132694 "Rho guanine nucleotide exchange factor 11" O15085 1 156934840-157045742 "Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 486.5;Tuft cells: 299.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011026, HPA012037, HPA014658" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 69: Skin cancer - ECM organization" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 16 "Plasma membrane" Nucleoplasm "HPA011026: , HPA012037: , HPA014658: " "unprognostic (1.28e-1)" "unprognostic (4.34e-2)" "unprognostic (8.45e-2)" "unprognostic (2.02e-2)" "unprognostic (1.51e-1)" "unprognostic (2.75e-2)" "unprognostic (7.87e-2)" "unprognostic (5.82e-3)" "unprognostic (1.96e-2)" "unprognostic (6.03e-2)" "potential prognostic favorable (3.67e-4)" "unprognostic (3.87e-2)" "unprognostic (2.25e-1)" "unprognostic (6.02e-2)" "unprognostic (2.18e-1)" "unprognostic (1.26e-1)" "unprognostic (6.19e-2)" "unprognostic (2.00e-2)" "unprognostic (6.34e-2)" "unprognostic (4.64e-2)" "unprognostic (2.23e-1)" "unprognostic (1.26e-1)" "unprognostic (3.55e-2)" "unprognostic (2.28e-1)" "unprognostic (2.73e-2)" "unprognostic (2.35e-1)" "unprognostic (2.69e-1)" "unprognostic (1.14e-1)" "unprognostic (1.94e-1)" "unprognostic (3.54e-2)" "unprognostic (2.33e-1)" ARHGEF12 "KIAA0382, LARG" ENSG00000196914 "Rho guanine nucleotide exchange factor 12" Q9NZN5 11 120336413-120489937 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Podocytes: 1102.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Lung - Endothelial cells, Spleen - Endothelial cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018911, CAB025581" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 63: Non-specific - Basic cellular processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 24: Non-specific - Unknown function" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 43 "Plasma membrane, Cytosol" Nucleoplasm "CAB025581: , HPA018911: " "unprognostic (5.66e-2)" "unprognostic (2.48e-2)" "unprognostic (5.30e-2)" "unprognostic (7.07e-2)" "unprognostic (2.82e-2)" "unprognostic (3.62e-3)" "unprognostic (7.14e-2)" "unprognostic (1.87e-2)" "unprognostic (7.50e-2)" "unprognostic (3.79e-2)" "validated prognostic favorable (6.51e-9)" "validated prognostic favorable (5.97e-5)" "unprognostic (6.87e-2)" "unprognostic (2.14e-1)" "unprognostic (1.43e-1)" "unprognostic (1.76e-1)" "unprognostic (3.92e-2)" "unprognostic (2.16e-1)" "unprognostic (1.91e-1)" "unprognostic (5.25e-2)" "unprognostic (8.71e-3)" "unprognostic (4.55e-3)" "unprognostic (5.80e-2)" "unprognostic (6.09e-2)" "unprognostic (2.68e-2)" "unprognostic (1.40e-1)" "unprognostic (1.87e-2)" "unprognostic (7.11e-2)" "unprognostic (5.04e-1)" "unprognostic (4.15e-1)" "unprognostic (7.87e-2)" ARHGEF15 "ARGEF15, FLJ13791, KIAA0915, MGC44868, Vsm-RhoGEF" ENSG00000198844 "Rho guanine nucleotide exchange factor 15" O94989 17 8310241-8322514 "Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 44.7;breast: 40.8" "Group enriched" "Detected in some" 4 "Lymphatic endothelial cells: 23.2;Vascular endothelial cells: 74.5" "Cell type enriched" "Detected in some" 8 "endothelial cell: 56.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "Sarcoma: 1.3" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044443, HPA063495" Supported "Plasma membrane" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 4 "Plasma membrane" "HPA044443: , HPA063495: " "unprognostic (1.44e-1)" "unprognostic (2.19e-1)" "unprognostic (3.16e-2)" "unprognostic (6.77e-3)" "unprognostic (6.74e-2)" "unprognostic (4.89e-2)" "unprognostic (2.01e-1)" "unprognostic (7.48e-2)" "unprognostic (3.18e-3)" "unprognostic (2.93e-2)" "validated prognostic favorable (3.14e-7)" "validated prognostic favorable (1.72e-4)" "unprognostic (9.51e-3)" "unprognostic (7.04e-2)" "potential prognostic favorable (1.13e-4)" "unprognostic (3.45e-2)" "unprognostic (6.21e-2)" "unprognostic (1.49e-2)" "unprognostic (1.45e-1)" "unprognostic (2.76e-1)" "unprognostic (1.20e-1)" "unprognostic (1.89e-2)" "unprognostic (4.36e-2)" "unprognostic (2.85e-2)" "unprognostic (1.97e-2)" "unprognostic (2.68e-1)" "unprognostic (2.50e-1)" "unprognostic (1.29e-2)" "unprognostic (1.72e-1)" "unprognostic (3.31e-1)" "unprognostic (5.76e-2)" ARHGEF16 "GEF16, NBR" ENSG00000130762 "Rho guanine nucleotide exchange factor 16" Q5VV41 1 3454665-3481113 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 41.4" "Cell type enhanced" "Detected in many" "Colonocytes: 79.2;Enterocytes: 76.1;Extravillous trophoblasts: 91.6;Foveolar cells: 63.1;Goblet cells: 69.0;Müller glia: 46.0;Salivary duct cells: 47.7;Tuft cells: 103.8" "Cell type enhanced" "Detected in many" "lower rhombic lip: 11.4;mammillary body: 17.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Breast - Breast glandular cells, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells" "Region enhanced" "Detected in many" "olfactory bulb: 4.7" "Low region specificity" "Detected in many" HPA010609 Approved NA NA "Cluster 77: Intestine - Digestion" "Cluster 49: Hindbrain - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 65: Non-specific - Cell growth & division" 22 "HPA010609: " "unprognostic (1.69e-1)" "unprognostic (2.36e-1)" "unprognostic (2.83e-2)" "unprognostic (2.04e-1)" "unprognostic (6.16e-3)" "unprognostic (2.09e-1)" "unprognostic (1.02e-1)" "unprognostic (3.71e-1)" "potential prognostic favorable (2.07e-7)" "unprognostic (2.95e-3)" "potential prognostic favorable (4.22e-5)" "potential prognostic unfavorable (5.29e-4)" "unprognostic (3.50e-1)" "unprognostic (4.22e-2)" "unprognostic (1.87e-1)" "unprognostic (2.12e-1)" "unprognostic (1.33e-1)" "unprognostic (4.49e-2)" "unprognostic (2.88e-2)" "unprognostic (1.01e-1)" "unprognostic (2.27e-1)" "unprognostic (8.40e-2)" "unprognostic (2.15e-2)" "unprognostic (2.44e-1)" "unprognostic (8.74e-3)" "unprognostic (1.22e-3)" "unprognostic (1.91e-1)" "unprognostic (1.88e-1)" "unprognostic (4.91e-2)" ARHGEF17 "KIAA0337, p164-RhoGEF, TEM4" ENSG00000110237 "Rho guanine nucleotide exchange factor 17" Q96PE2 11 73308276-73369388 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pericytes: 176.6;Podocytes: 79.8;Vascular smooth muscle cells: 133.7" "Cell type enhanced" "Detected in all" "pericyte: 233.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007991, HPA074658" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 110: Mural cells - ECM organization" 10 Cytosol "Plasma membrane" "HPA007991: , HPA074658: " "unprognostic (1.41e-2)" "unprognostic (1.42e-1)" "unprognostic (2.89e-2)" "unprognostic (1.49e-3)" "unprognostic (2.32e-3)" "unprognostic (7.96e-2)" "unprognostic (2.30e-1)" "unprognostic (6.41e-3)" "unprognostic (1.51e-2)" "unprognostic (1.09e-1)" "validated prognostic favorable (7.72e-4)" "validated prognostic favorable (9.90e-4)" "unprognostic (7.15e-2)" "unprognostic (1.01e-1)" "unprognostic (3.11e-2)" "unprognostic (2.28e-2)" "unprognostic (3.47e-2)" "unprognostic (9.04e-2)" "unprognostic (2.74e-1)" "potential prognostic unfavorable (2.06e-4)" "unprognostic (9.82e-2)" "unprognostic (9.29e-2)" "unprognostic (4.62e-2)" "unprognostic (2.28e-1)" "unprognostic (7.63e-2)" "unprognostic (7.13e-2)" "unprognostic (3.37e-1)" "unprognostic (2.02e-2)" "unprognostic (3.74e-2)" "unprognostic (7.00e-2)" "unprognostic (1.64e-1)" ARHGEF18 "KIAA0521, MGC15913, P114-RhoGEF, p114RhoGEF" ENSG00000104880 "Rho/Rac guanine nucleotide exchange factor 18" Q6ZSZ5 19 7348937-7472485 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 600.2;Esophageal apical cells: 269.8;Monocyte progenitors: 492.4;Neutrophil progenitors: 402.1;Neutrophils: 336.1;Thymocytes: 626.7" "Cell type enhanced" "Detected in all" "leukocyte: 135.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular), Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042689, HPA049151, HPA071867" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 11: White matter - Signal transduction" "Cluster 23: Non-specific - Transcription" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 3 Cytosol "Plasma membrane" "HPA042689: , HPA049151: , HPA071867: " "unprognostic (1.45e-3)" "unprognostic (2.40e-1)" "unprognostic (1.47e-1)" "unprognostic (1.49e-3)" "unprognostic (1.29e-1)" "unprognostic (3.49e-1)" "unprognostic (1.03e-1)" "unprognostic (6.81e-3)" "unprognostic (2.91e-3)" "unprognostic (4.11e-1)" "potential prognostic favorable (2.29e-5)" "unprognostic (1.64e-1)" "unprognostic (3.41e-2)" "unprognostic (4.26e-2)" "unprognostic (6.40e-2)" "unprognostic (7.46e-2)" "unprognostic (2.09e-1)" "unprognostic (1.17e-2)" "unprognostic (1.82e-1)" "unprognostic (1.62e-1)" "unprognostic (3.03e-1)" "unprognostic (1.27e-1)" "unprognostic (5.93e-2)" "unprognostic (1.05e-1)" "unprognostic (5.04e-2)" "unprognostic (5.62e-2)" "unprognostic (2.33e-3)" "unprognostic (3.79e-1)" "unprognostic (2.38e-1)" "unprognostic (1.08e-1)" "unprognostic (2.29e-2)" ARHGEF19 "FLJ33962, WGEF" ENSG00000142632 "Rho guanine nucleotide exchange factor 19" Q8IW93 1 16197854-16212652 "Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 26.8" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 23.4;Paneth cells: 27.1" "Cell type enhanced" "Detected in some" "endothelial cell: 7.2;leukocyte: 5.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA068108 Approved "Nuclear bodies" No No "Cluster 33: Non-specific - ATP binding" "Cluster 58: Skin - Keratinization" "Cluster 44: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 1 "Nuclear bodies" "HPA068108: " "unprognostic (2.70e-1)" "unprognostic (2.25e-1)" "unprognostic (1.19e-1)" "unprognostic (3.32e-1)" "unprognostic (5.17e-2)" "unprognostic (3.72e-1)" "unprognostic (1.84e-2)" "unprognostic (4.92e-2)" "unprognostic (2.98e-3)" "unprognostic (2.34e-3)" "unprognostic (2.70e-2)" "unprognostic (2.74e-2)" "unprognostic (9.07e-2)" "unprognostic (1.67e-2)" "unprognostic (5.27e-2)" "unprognostic (9.30e-2)" "unprognostic (3.62e-2)" "unprognostic (7.04e-2)" "unprognostic (1.70e-1)" "unprognostic (4.33e-2)" "unprognostic (3.09e-3)" "potential prognostic unfavorable (5.35e-4)" "unprognostic (1.53e-1)" "unprognostic (1.61e-1)" "unprognostic (9.80e-3)" "unprognostic (1.88e-1)" "unprognostic (5.49e-2)" "unprognostic (2.17e-1)" "unprognostic (7.04e-2)" "unprognostic (2.60e-3)" ARHGEF2 "GEF-H1, GEFH1, KIAA0651, Lfc, LFP40, P40" ENSG00000116584 "Rho/Rac guanine nucleotide exchange factor 2" Q92974 1 155946851-156007070 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Immunity, Innate immunity, Mitosis, Neurogenesis" "Developmental protein, Guanine-nucleotide releasing factor" "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 142.6;Neutrophils: 246.3;Oligodendrocytes: 139.9" "Cell type enhanced" "Detected in all" "oligodendrocyte: 175.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Skin - Endothelial cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043437 Approved NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 5: Spleen - Immune response" "Cluster 30: White matter - Myelination" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 62 "HPA043437: " "unprognostic (9.29e-2)" "unprognostic (1.79e-1)" "unprognostic (1.62e-1)" "potential prognostic unfavorable (9.66e-4)" "unprognostic (9.94e-2)" "unprognostic (3.10e-1)" "unprognostic (2.32e-2)" "unprognostic (3.43e-3)" "unprognostic (2.35e-1)" "unprognostic (1.82e-3)" "unprognostic (1.15e-1)" "unprognostic (1.09e-1)" "unprognostic (1.64e-1)" "potential prognostic unfavorable (1.33e-4)" "unprognostic (2.67e-2)" "unprognostic (1.40e-2)" "unprognostic (1.60e-1)" "unprognostic (1.19e-1)" "unprognostic (1.63e-1)" "unprognostic (5.16e-2)" "unprognostic (1.95e-1)" "unprognostic (2.39e-1)" "unprognostic (1.77e-1)" "unprognostic (5.29e-1)" "unprognostic (3.41e-2)" "unprognostic (2.00e-1)" "unprognostic (2.84e-2)" "unprognostic (1.33e-1)" "unprognostic (3.03e-1)" "unprognostic (2.46e-2)" "unprognostic (1.36e-1)" ARHGEF25 "GEFT, p63RhoGEF" ENSG00000240771 "Rho guanine nucleotide exchange factor 25" Q86VW2 12 57610180-57617245 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 1.7;Endometrial stromal cells: 3.3;Fibro-adipogenic progenitors: 3.3;Fibroblasts: 1.9;Mesothelial cells: 2.5;Pericytes: 5.4;Podocytes: 3.4;Retinal amacrine cells: 2.5;Salivary myoepithelial cells: 1.6;Smooth muscle cells: 5.1;Vascular smooth muscle cells: 7.8" "Cell type enhanced" "Detected in some" "vascular associated smooth muscle cell: 4.4" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 63.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Smooth muscle cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052016 Approved NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 62: Smooth muscle cells - Muscle contraction" 1 "HPA052016: " "potential prognostic favorable (3.46e-4)" "unprognostic (3.79e-1)" "unprognostic (4.13e-2)" "unprognostic (9.54e-3)" "unprognostic (1.42e-1)" "unprognostic (1.05e-1)" "unprognostic (2.10e-3)" "unprognostic (2.24e-2)" "potential prognostic unfavorable (9.84e-5)" "unprognostic (8.10e-3)" "unprognostic (9.40e-2)" "unprognostic (8.07e-2)" "unprognostic (2.63e-1)" "unprognostic (6.44e-3)" "unprognostic (1.58e-2)" "unprognostic (4.01e-3)" "unprognostic (2.12e-1)" "unprognostic (1.04e-1)" "unprognostic (1.82e-2)" "unprognostic (1.18e-1)" "unprognostic (2.30e-2)" "unprognostic (3.75e-1)" "unprognostic (1.04e-1)" "unprognostic (3.73e-2)" "unprognostic (7.60e-2)" "unprognostic (4.13e-2)" "unprognostic (1.19e-2)" "unprognostic (2.23e-1)" "unprognostic (5.38e-3)" "unprognostic (1.03e-2)" ARHGEF26 "DKFZP434D146, SGEF" ENSG00000114790 "Rho guanine nucleotide exchange factor 26" Q96DR7 3 154121003-154257827 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 6 "Astrocytes: 341.7;Bergmann glia: 389.7;Choroid plexus epithelial cells: 306.7;Ependymal cells: 260.7;Podocytes: 836.0" "Group enriched" "Detected in all" 4 "astrocyte: 375.8;Bergmann glia: 418.7;choroid plexus epithelial cell: 261.6;ependymal cell: 281.0" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 12.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Podocytes, Lung - Alveolar cells type 1, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017722, HPA049195" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 39: Astrocytes - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 28: Astrocytes - Homeostasis & neuron support" 5 "Plasma membrane" "Nucleoplasm, Cytosol" "HPA017722: , HPA049195: " "unprognostic (8.42e-3)" "unprognostic (1.27e-1)" "unprognostic (1.07e-1)" "unprognostic (8.44e-2)" "unprognostic (2.13e-1)" "unprognostic (9.65e-3)" "unprognostic (1.72e-2)" "unprognostic (1.95e-2)" "unprognostic (3.14e-3)" "unprognostic (1.33e-1)" "unprognostic (8.35e-2)" "unprognostic (1.41e-1)" "potential prognostic favorable (4.92e-4)" "unprognostic (1.79e-2)" "unprognostic (5.15e-3)" "unprognostic (3.88e-1)" "unprognostic (5.87e-2)" "unprognostic (1.07e-1)" "unprognostic (1.64e-1)" "unprognostic (5.91e-2)" "unprognostic (1.52e-2)" "unprognostic (2.30e-1)" "unprognostic (1.57e-1)" ARHGEF28 "p190RhoGEF, RGNEF, RIP2" ENSG00000214944 "Rho guanine nucleotide exchange factor 28" Q8N1W1 5 73626158-73941993 "Predicted intracellular proteins" Differentiation "Guanine-nucleotide releasing factor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 1081.8;Bergmann glia: 549.8;Lacrimal acinar cells: 446.6;Proximal tubule cells: 444.5;Renal collecting duct intercalated cells: 571.9;Salivary acinar cells: 433.4;Salivary ionocytes: 592.0" "Cell type enhanced" "Detected in all" "Bergmann glia: 563.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Breast - Breast myoepithelial cells, Pituitary gland - Somatotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037602 Enhanced Approved "Plasma membrane,Microtubules,Cytosol" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 14: Neurons - Synaptic function" "Cluster 72: Neuronal - Signal transduction" "Cluster 18: Adrenal cortex cells - Steroidogensis" 1 "Microtubules, Cytosol" "Plasma membrane" "HPA037602: " "unprognostic (1.50e-1)" "unprognostic (1.92e-1)" "unprognostic (3.69e-2)" "unprognostic (1.21e-1)" "unprognostic (2.80e-2)" "unprognostic (1.51e-3)" "unprognostic (1.36e-2)" "unprognostic (3.41e-2)" "unprognostic (2.71e-1)" "potential prognostic favorable (2.68e-11)" "unprognostic (3.47e-3)" "unprognostic (7.65e-2)" "unprognostic (1.05e-1)" "unprognostic (1.67e-1)" "unprognostic (1.32e-1)" "unprognostic (1.34e-1)" "unprognostic (2.57e-2)" "unprognostic (1.59e-1)" "unprognostic (1.30e-1)" "unprognostic (2.62e-1)" "unprognostic (7.57e-2)" "unprognostic (7.39e-2)" "unprognostic (1.22e-2)" "unprognostic (1.06e-1)" "unprognostic (2.06e-1)" "unprognostic (1.68e-1)" "unprognostic (4.74e-2)" "unprognostic (3.19e-2)" "unprognostic (2.21e-1)" ARHGEF3 "DKFZP434F2429, GEF3, STA3, XPLN" ENSG00000163947 "Rho guanine nucleotide exchange factor 3" Q9NR81 3 56727418-57079329 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 754.1;Distal convoluted tubule cells: 606.8;Podocytes: 1579.6;Sertoli cells: 857.3" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 646.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Pituitary gland - Undifferentiated cells (Pituitary gland)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034715, HPA064945" Uncertain Approved Cytosol NA NA "Cluster 27: T-cells - Unknown function" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 15 Cytosol "HPA034715: , HPA064945: " "unprognostic (3.03e-3)" "unprognostic (9.02e-2)" "unprognostic (2.03e-1)" "unprognostic (2.34e-1)" "unprognostic (2.39e-1)" "unprognostic (8.27e-2)" "unprognostic (1.99e-1)" "unprognostic (8.70e-2)" "unprognostic (3.07e-3)" "unprognostic (4.20e-2)" "potential prognostic favorable (3.16e-7)" "unprognostic (1.64e-2)" "unprognostic (4.78e-2)" "unprognostic (6.71e-2)" "unprognostic (9.81e-2)" "unprognostic (1.94e-2)" "unprognostic (2.58e-2)" "unprognostic (2.21e-2)" "unprognostic (2.93e-2)" "unprognostic (2.10e-1)" "unprognostic (8.02e-2)" "unprognostic (9.77e-2)" "unprognostic (1.55e-1)" "unprognostic (2.29e-2)" "potential prognostic favorable (9.02e-5)" "unprognostic (5.02e-2)" "unprognostic (2.54e-1)" "unprognostic (4.30e-2)" "unprognostic (9.10e-2)" "potential prognostic unfavorable (2.08e-4)" "unprognostic (7.46e-3)" ARHGEF33 ENSG00000214694 "Rho guanine nucleotide exchange factor 33" A8MVX0 2 38889875-38975454 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.5;testis: 10.4" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 28.6;Cardiomyocytes: 37.4;Choroid plexus epithelial cells: 26.6;Differentiating spermatogonia: 30.2;Early primary spermatocytes: 41.4;Early spermatids: 34.4;Ependymal cells: 70.7;Late primary spermatocytes: 51.4;Late spermatids: 32.1;Oocytes: 46.1;Respiratory ciliated cells: 27.0;Undifferentiated spermatogonia: 30.1" "Cell type enhanced" "Detected in many" "midbrain-derived inhibitory: 119.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 12 "eosinophil: 4.7" "Lineage enriched" "Detected in single" 12 "granulocytes: 4.7" "Cancer enhanced" "Detected in some" "cervical cancer: 3.7" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in many" 32 "cerebellum: 280.4" "Region enriched" "Detected in all" 8 "cerebellum: 51.8" "HPA034661, HPA041051" Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 71: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 4: Non-specific - Transcription" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" Vesicles "Nucleoplasm, Cytosol" "HPA034661: , HPA041051: " "unprognostic (1.15e-1)" "unprognostic (2.69e-3)" "unprognostic (1.44e-1)" "unprognostic (6.86e-2)" "unprognostic (2.00e-1)" "unprognostic (4.29e-2)" ARHGEF35 "ARHGEF5L, CTAGE4, FLJ43692" ENSG00000213214 "Rho guanine nucleotide exchange factor 35" A5YM69 7 144186083-144195879 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 5.7;Endometrial ciliated cells: 4.1;Endometrial luminal cells: 6.5;Epididymal basal cells: 3.6;Extravillous trophoblasts: 3.4;Foveolar cells: 3.6;Gastric chief cells: 4.4;Loop of henle epithelial cells: 3.8;Ocular epithelial cells: 3.4;Proximal tubule cells: 3.4;Suprabasal keratinocytes: 5.6" "Cell type enhanced" "Detected in single" "choroid plexus epithelial cell: 3.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells" "HPA044188, HPA045619, HPA045699" Supported NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 72: Kidney - Transmembrane transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 3 "HPA044188: , HPA045619: , HPA045699: " "unprognostic (1.55e-2)" "unprognostic (1.49e-1)" "unprognostic (1.76e-1)" "unprognostic (3.30e-1)" "unprognostic (5.74e-2)" "unprognostic (2.23e-1)" "unprognostic (2.67e-1)" "unprognostic (1.28e-1)" "unprognostic (1.63e-2)" "unprognostic (6.16e-2)" "unprognostic (3.10e-1)" "potential prognostic unfavorable (2.19e-4)" "unprognostic (1.24e-1)" "unprognostic (6.16e-3)" "unprognostic (5.43e-2)" "unprognostic (7.40e-2)" "unprognostic (9.25e-2)" "unprognostic (1.39e-2)" "unprognostic (3.88e-2)" "unprognostic (3.64e-1)" "unprognostic (7.94e-2)" "unprognostic (1.25e-1)" "unprognostic (1.01e-1)" "unprognostic (2.95e-2)" "unprognostic (9.10e-2)" "unprognostic (3.83e-1)" "unprognostic (5.05e-2)" "unprognostic (4.83e-2)" "unprognostic (3.47e-1)" ARHGEF37 FLJ41603 ENSG00000183111 "Rho guanine nucleotide exchange factor 37" A1IGU5 5 149551947-149634968 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 58.1" "Cell type enhanced" "Detected in many" "Lacrimal acinar cells: 94.2;Müller glia: 111.4;Podocytes: 118.5;Prostatic glandular cells: 120.2;Salivary acinar cells: 96.7" "Cell type enhanced" "Detected in all" "oligodendrocyte: 133.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "basophil: 9.3;neutrophil: 3.1" "Lineage enriched" "Detected in single" 12 "granulocytes: 9.3" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 22.3" "Adipose subcutaneous - Smooth muscle cells, Breast - Breast glandular cells, Prostate - Prostate glandular cells" "Region enhanced" "Detected in many" "cerebellum: 10.4" "Low region specificity" "Detected in all" "HPA043885, HPA053487" Uncertain Approved Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 1 Cytosol "HPA043885: , HPA053487: " "unprognostic (1.78e-1)" "unprognostic (3.69e-2)" "unprognostic (9.37e-2)" "unprognostic (3.73e-2)" "unprognostic (2.71e-1)" "unprognostic (2.30e-1)" "unprognostic (4.61e-2)" "unprognostic (9.11e-3)" "unprognostic (1.75e-2)" "unprognostic (7.05e-2)" "validated prognostic favorable (6.23e-7)" "validated prognostic favorable (6.28e-6)" "potential prognostic favorable (9.05e-5)" "unprognostic (1.04e-3)" "unprognostic (3.85e-1)" "unprognostic (1.28e-1)" "unprognostic (3.90e-2)" "unprognostic (2.10e-1)" "unprognostic (2.44e-1)" "unprognostic (3.85e-2)" "unprognostic (4.05e-2)" "unprognostic (4.92e-2)" "unprognostic (3.56e-2)" "unprognostic (4.58e-2)" "unprognostic (6.19e-2)" "unprognostic (4.11e-1)" "unprognostic (2.56e-1)" "unprognostic (7.04e-2)" "unprognostic (1.06e-1)" "unprognostic (4.54e-3)" "unprognostic (2.29e-1)" ARHGEF38 FLJ20184 ENSG00000236699 "Rho guanine nucleotide exchange factor 38" Q9NXL2 4 105552620-105708093 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 7.4;pancreas: 6.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 245.4;Goblet cells: 200.4;Loop of henle epithelial cells: 228.9;Paneth cells: 224.3;Prostatic glandular cells: 439.2;Renal connecting tubule cells: 220.9;Respiratory ciliated cells: 208.5;Salivary ionocytes: 193.2;Transitional alveolar cells: 207.9;Tuft cells: 507.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 13.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 3.9;prostate cancer: 4.3" "Breast - Breast glandular cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA036510, HPA045484" Uncertain Approved Nucleoplasm,Centrosome NA NA "Cluster 60: Stomach - Digestion" "Cluster 27: Breast cancer - Unknown function" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" Nucleoplasm Centrosome "HPA036510: , HPA045484: " "unprognostic (2.95e-1)" "unprognostic (7.35e-2)" "unprognostic (1.59e-1)" "unprognostic (1.92e-1)" "unprognostic (2.00e-1)" "unprognostic (1.46e-1)" "unprognostic (2.20e-3)" "unprognostic (5.08e-3)" "unprognostic (6.39e-2)" "unprognostic (3.31e-1)" "unprognostic (1.99e-1)" "unprognostic (1.67e-1)" "unprognostic (4.62e-3)" "unprognostic (8.27e-2)" "unprognostic (3.41e-1)" "unprognostic (2.17e-3)" "unprognostic (3.91e-3)" "unprognostic (1.79e-1)" ARHGEF39 "C9orf100, FLJ14642" ENSG00000137135 "Rho guanine nucleotide exchange factor 39" Q8N4T4 9 35658875-35675866 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 11.9" "Cell type enhanced" "Detected in many" "Adipocytes: 73.3;Cardiomyocytes: 125.2;Early spermatids: 133.2;Epicardial cells: 54.6;Extravillous trophoblasts: 21.8;Late primary spermatocytes: 23.5;Late spermatids: 50.8;Monocyte progenitors: 21.3;Vascular smooth muscle cells: 22.4" "Cell type enhanced" "Detected in some" "vascular associated smooth muscle cell: 4.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in single" 4 "basal ganglia: 2.7" "Low region specificity" "Detected in all" HPA061299 Uncertain NA Yes "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 15: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 4 "HPA061299: " "unprognostic (1.72e-1)" "unprognostic (2.25e-1)" "unprognostic (1.26e-1)" "unprognostic (2.79e-1)" "unprognostic (3.75e-2)" "unprognostic (2.07e-1)" "unprognostic (2.94e-2)" "unprognostic (2.32e-1)" "potential prognostic unfavorable (1.16e-8)" "unprognostic (1.12e-2)" "unprognostic (9.20e-2)" "potential prognostic unfavorable (5.17e-5)" "unprognostic (1.17e-3)" "potential prognostic unfavorable (3.12e-4)" "unprognostic (2.15e-1)" "unprognostic (6.48e-2)" "unprognostic (3.10e-3)" "unprognostic (1.79e-2)" "unprognostic (2.29e-1)" "unprognostic (1.80e-1)" "unprognostic (2.92e-1)" "unprognostic (3.69e-1)" "unprognostic (3.10e-1)" "unprognostic (4.52e-2)" "unprognostic (4.84e-3)" "unprognostic (3.30e-1)" "unprognostic (9.66e-2)" ARHGEF4 "ASEF, ASEF1, KIAA1112, STM6" ENSG00000136002 "Rho guanine nucleotide exchange factor 4" Q9NR80 2 130836914-131047263 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 96.3" "Cell type enhanced" "Detected in many" "Astrocytes: 541.1;Basal keratinocytes: 139.9;Bergmann glia: 205.4;Brain inhibitory neurons: 134.5;Choroid plexus epithelial cells: 290.5;Cone photoreceptor cells: 190.5;Corticotrophs: 212.5;Endometrial glandular cells: 151.7;Esophageal apical cells: 247.6;Esophageal suprabasal cells: 165.2;Ocular epithelial cells: 229.0;Oligodendrocyte progenitor cells: 257.0;Pituicytes/FSCs: 158.7;Suprabasal keratinocytes: 236.8" "Cell type enhanced" "Detected in all" "astrocyte: 766.9" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 22.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD8 T-cell: 1.4" "Group enriched" "Detected in many" 12 "dendritic cells: 1.0;T-cells: 1.4" "Cancer enhanced" "Detected in many" "Esophageal cancer: 18.6" "Adrenal gland - Adrenal medulla cells, Minor Salivary Gland - Minor salivary gland basal cells, Skeletal muscle - Skeletal myocytes, Stomach - Fibroblasts" HPA018267 Approved NA NA "Cluster 11: T-cells - Unknown function" "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 28: Astrocytes - Homeostasis & neuron support" 9 "HPA018267: " "unprognostic (5.03e-3)" "unprognostic (7.44e-3)" "unprognostic (8.97e-2)" "unprognostic (1.98e-2)" "unprognostic (1.42e-1)" "unprognostic (2.70e-1)" "unprognostic (1.06e-2)" "unprognostic (1.49e-3)" "potential prognostic unfavorable (3.01e-5)" "unprognostic (5.50e-2)" "unprognostic (4.00e-2)" "unprognostic (4.17e-3)" "unprognostic (4.29e-2)" "unprognostic (2.23e-1)" "unprognostic (1.71e-2)" "unprognostic (3.28e-3)" "unprognostic (1.42e-1)" "unprognostic (5.25e-3)" "unprognostic (2.49e-2)" "unprognostic (9.95e-3)" "potential prognostic favorable (1.43e-4)" "unprognostic (6.59e-3)" "unprognostic (6.30e-2)" ARHGEF40 "FLJ10357, solo" ENSG00000165801 "Rho guanine nucleotide exchange factor 40" Q8TER5 14 21070273-21090248 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 95.0;Adrenal cortex cells: 146.9;Neutrophils: 404.7" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 85.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 6.2" "Lineage enriched" "Detected in many" 6 "granulocytes: 6.2" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030745, HPA030746, HPA030757" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 24: Neutrophils - Innate immunity signal integration" 1 "Plasma membrane, Cytosol" "HPA030745: , HPA030746: , HPA030757: " "unprognostic (1.53e-1)" "unprognostic (5.21e-2)" "unprognostic (1.98e-1)" "unprognostic (4.23e-2)" "unprognostic (1.67e-1)" "unprognostic (2.46e-1)" "unprognostic (4.72e-2)" "unprognostic (9.47e-2)" "unprognostic (5.73e-2)" "potential prognostic favorable (1.05e-5)" "unprognostic (3.52e-3)" "unprognostic (3.32e-2)" "unprognostic (2.12e-1)" "unprognostic (1.18e-1)" "unprognostic (1.27e-1)" "unprognostic (3.63e-1)" "unprognostic (5.65e-2)" "unprognostic (3.70e-1)" "unprognostic (2.07e-1)" "unprognostic (2.31e-1)" "unprognostic (1.56e-2)" "unprognostic (1.59e-1)" "unprognostic (1.82e-1)" "unprognostic (3.72e-1)" "unprognostic (1.15e-1)" "unprognostic (4.19e-1)" "unprognostic (4.37e-2)" "unprognostic (1.71e-1)" "unprognostic (2.65e-1)" "unprognostic (1.30e-1)" ARHGEF5 "GEF5, P60, TIM, TIM1" ENSG00000050327 "Rho guanine nucleotide exchange factor 5" Q12774 7 144355288-144380632 "Essential proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 45.2" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 8.9;Foveolar cells: 8.0;Loop of henle epithelial cells: 15.5;Ocular epithelial cells: 13.7;Papillary tip epithelial cells: 8.8;Proximal tubule cells: 12.8;Renal collecting duct intercalated cells: 12.7;Renal collecting duct principal cells: 15.1;Renal connecting tubule cells: 12.9;Tuft cells: 11.5" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 4.3;fibroblast: 2.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.8" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Stomach - Gastric mucous cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA020980, HPA029504, HPA044188, HPA045619, HPA045699" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 58: Skin - Keratinization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 15: Kidney cancer - Membrane components" "Cluster 100: Stratified epithelial cells - Barrier functions" 30 "Plasma membrane, Cytosol" Nucleoplasm "HPA020980: , HPA029504: , HPA044188: , HPA045619: , HPA045699: " "unprognostic (5.02e-2)" "unprognostic (1.24e-1)" "unprognostic (2.84e-1)" "unprognostic (8.43e-3)" "unprognostic (2.15e-1)" "unprognostic (1.09e-1)" "unprognostic (4.82e-2)" "unprognostic (2.71e-2)" "unprognostic (2.52e-2)" "unprognostic (2.04e-1)" "unprognostic (1.84e-1)" "unprognostic (6.01e-2)" "unprognostic (2.73e-1)" "unprognostic (9.35e-3)" "unprognostic (1.44e-1)" "unprognostic (1.81e-1)" "unprognostic (1.27e-2)" "unprognostic (9.99e-2)" "potential prognostic unfavorable (9.53e-4)" "unprognostic (5.40e-2)" "unprognostic (1.33e-1)" "unprognostic (3.40e-1)" "unprognostic (1.87e-1)" "unprognostic (2.09e-1)" "unprognostic (5.69e-2)" "unprognostic (2.04e-2)" "unprognostic (1.15e-1)" "unprognostic (2.02e-1)" "unprognostic (4.64e-2)" ARHGEF6 "alpha-PIX, alphaPIX, Cool-2, Cool2, KIAA0006, MRX46" ENSG00000129675 "Rac/Cdc42 guanine nucleotide exchange factor 6" Q15052 X 136665547-136780932 "Cancer-related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 205.5;Astrocytes: 114.3;Hematopoietic stem cells: 148.0;Mast cells: 249.4;Microglia: 250.7;Monocyte progenitors: 115.7;Myonuclei: 183.8;Neutrophil progenitors: 197.2;Thymocytes: 112.6" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 311.9" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 52.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 97.4;lymphoma: 38.7" "Colon - Enteric glia cells, Prostate - Fibroblasts, Skeletal muscle - Skeletal myocytes, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003578, HPA071036" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 58: Mast cells - Allergic inflammatory responses" 38 "Plasma membrane, Cytosol" "HPA003578: , HPA071036: " "unprognostic (5.40e-3)" "unprognostic (1.02e-1)" "unprognostic (1.48e-1)" "unprognostic (3.61e-2)" "unprognostic (5.31e-2)" "unprognostic (4.80e-2)" "unprognostic (1.40e-2)" "unprognostic (8.73e-2)" "unprognostic (2.55e-3)" "unprognostic (6.01e-3)" "unprognostic (4.23e-2)" "unprognostic (2.37e-1)" "unprognostic (2.59e-2)" "unprognostic (1.36e-1)" "unprognostic (3.31e-2)" "potential prognostic favorable (5.10e-5)" "unprognostic (2.30e-2)" "unprognostic (1.31e-1)" "unprognostic (1.07e-1)" "unprognostic (1.32e-1)" "unprognostic (2.68e-1)" "unprognostic (1.94e-1)" "unprognostic (2.27e-1)" "unprognostic (1.65e-1)" "unprognostic (2.15e-1)" "unprognostic (3.82e-2)" "unprognostic (1.88e-1)" "unprognostic (3.23e-2)" "unprognostic (4.51e-3)" "unprognostic (2.38e-1)" "unprognostic (3.10e-2)" ARHGEF7 "BETA-PIX, COOL1, DKFZp686C12170, DKFZp761K1021, KIAA0142, Nbla10314, P50, P50BP, P85, P85COOL1, P85SPR, PAK3, PIXB" ENSG00000102606 "Rho guanine nucleotide exchange factor 7" Q14155 13 111114559-111305737 "Predicted intracellular proteins" Neurogenesis "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Vascular smooth muscle cells: 423.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004744 Approved NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 66 "HPA004744: " "potential prognostic favorable (1.54e-4)" "unprognostic (1.45e-1)" "unprognostic (2.87e-1)" "unprognostic (1.81e-2)" "unprognostic (1.52e-1)" "unprognostic (4.63e-2)" "unprognostic (1.54e-2)" "potential prognostic favorable (3.40e-4)" "unprognostic (2.68e-1)" "unprognostic (1.02e-1)" "potential prognostic favorable (2.71e-4)" "unprognostic (3.64e-3)" "unprognostic (2.77e-2)" "unprognostic (5.41e-3)" "unprognostic (2.17e-2)" "unprognostic (2.31e-1)" "unprognostic (9.61e-3)" "unprognostic (1.02e-1)" "unprognostic (3.65e-2)" "unprognostic (1.83e-3)" "unprognostic (2.28e-1)" "unprognostic (1.52e-1)" "unprognostic (1.43e-2)" "unprognostic (1.42e-1)" "unprognostic (7.33e-2)" "unprognostic (2.38e-1)" "unprognostic (4.11e-1)" "unprognostic (1.24e-1)" "unprognostic (2.19e-1)" "unprognostic (1.15e-2)" "unprognostic (7.53e-2)" ARHGEF9 "KIAA0424, PEM-2" ENSG00000131089 "Cdc42 guanine nucleotide exchange factor 9" O43307 X 63634967-63809274 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 68.4;retina: 81.7" "Cell type enhanced" "Detected in many" "Breast lactating cells: 233.3;Cone photoreceptor cells: 383.0;Corticotrophs: 252.6;Retinal bipolar cells: 218.6;Rod photoreceptor cells: 464.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035419, HPA055291" Approved Supported Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 36: Non-specific - mRNA processing" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 12 Cytosol "HPA035419: , HPA055291: " "unprognostic (1.17e-1)" "unprognostic (3.40e-1)" "unprognostic (8.13e-2)" "unprognostic (7.95e-2)" "unprognostic (9.45e-2)" "unprognostic (1.87e-1)" "unprognostic (1.66e-1)" "potential prognostic favorable (1.68e-4)" "unprognostic (2.91e-1)" "unprognostic (7.86e-2)" "potential prognostic favorable (6.64e-8)" "unprognostic (7.30e-3)" "unprognostic (5.21e-3)" "unprognostic (2.77e-1)" "unprognostic (1.95e-1)" "unprognostic (8.55e-2)" "unprognostic (6.89e-2)" "unprognostic (2.55e-1)" "unprognostic (7.34e-3)" "unprognostic (2.20e-2)" "unprognostic (1.12e-1)" "unprognostic (4.59e-3)" "unprognostic (3.83e-1)" "unprognostic (1.78e-2)" "unprognostic (1.67e-1)" "unprognostic (1.75e-1)" "unprognostic (1.26e-1)" "unprognostic (1.19e-1)" "unprognostic (2.13e-2)" "unprognostic (2.20e-2)" "unprognostic (3.74e-1)" ARID1A "B120, BAF250, BAF250a, C10rf4, C1orf4, P270, SMARCF1" ENSG00000117713 "AT-rich interaction domain 1A" O14497 1 26693236-26782104 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Neurogenesis, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Cancer-related genes, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005456, CAB016334" Supported Supported Nucleoplasm NA Yes "Cluster 7: Non-specific - Innate immune response" "Cluster 80: Thymus - Adaptive immune response" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 37: Non-specific - mRNA processing" "Cluster 7: Non-specific - Transcription" 89 Nucleoplasm "CAB016334: , HPA005456: " "unprognostic (9.14e-3)" "unprognostic (1.13e-1)" "unprognostic (4.03e-1)" "unprognostic (1.03e-1)" "unprognostic (8.94e-2)" "unprognostic (4.37e-3)" "unprognostic (3.27e-1)" "unprognostic (2.16e-1)" "unprognostic (4.63e-2)" "unprognostic (1.37e-2)" "potential prognostic favorable (1.00e-4)" "unprognostic (1.04e-2)" "unprognostic (1.76e-1)" "potential prognostic unfavorable (2.65e-4)" "unprognostic (1.07e-1)" "unprognostic (3.47e-1)" "unprognostic (4.26e-2)" "unprognostic (1.34e-1)" "unprognostic (1.93e-1)" "unprognostic (2.09e-2)" "unprognostic (4.54e-1)" "unprognostic (2.12e-1)" "unprognostic (2.62e-1)" "unprognostic (1.38e-1)" "unprognostic (3.10e-1)" "unprognostic (1.48e-1)" "unprognostic (4.60e-2)" "unprognostic (2.10e-1)" "unprognostic (2.63e-1)" "unprognostic (2.31e-1)" "unprognostic (2.08e-1)" ARID1B "6A3-5, BAF250b, DAN15, ELD/OSA1, KIAA1235, p250R, SMARCF2" ENSG00000049618 "AT-rich interaction domain 1B" Q8NFD5 6 156776020-157210779 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Neurogenesis, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Cancer-related genes, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016511, HPA075291" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 15: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" 65 Nucleoplasm "Plasma membrane, Cytosol" "HPA016511: , HPA075291: " "unprognostic (7.41e-3)" "potential prognostic unfavorable (1.01e-5)" "unprognostic (3.87e-3)" "unprognostic (5.63e-3)" "unprognostic (7.64e-2)" "unprognostic (1.66e-1)" "unprognostic (9.44e-2)" "unprognostic (4.95e-2)" "unprognostic (1.77e-2)" "unprognostic (6.03e-2)" "potential prognostic favorable (1.12e-4)" "unprognostic (1.41e-2)" "unprognostic (2.37e-2)" "potential prognostic unfavorable (2.90e-4)" "unprognostic (4.49e-1)" "unprognostic (9.38e-2)" "unprognostic (1.84e-1)" "unprognostic (1.45e-1)" "unprognostic (1.29e-1)" "unprognostic (1.03e-3)" "unprognostic (1.08e-1)" "unprognostic (2.08e-1)" "unprognostic (5.28e-2)" "unprognostic (1.63e-1)" "unprognostic (5.47e-3)" "unprognostic (4.10e-3)" "unprognostic (1.19e-1)" "unprognostic (2.90e-1)" "unprognostic (3.19e-1)" "unprognostic (3.10e-1)" "unprognostic (6.47e-2)" ARID2 "BAF200, DKFZp686G052, FLJ30619, KIAA1557, SMARCF3" ENSG00000189079 "AT-rich interaction domain 2" Q68CP9 12 45729706-45908040 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 699.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063044, HPA078115" Supported Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 39: Testis - Nuclear processes" "Cluster 25: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 34 Nucleoplasm "HPA063044: , HPA078115: " "unprognostic (6.30e-2)" "unprognostic (7.95e-2)" "unprognostic (1.28e-1)" "unprognostic (2.41e-2)" "unprognostic (4.98e-2)" "unprognostic (1.11e-2)" "unprognostic (9.40e-2)" "unprognostic (9.73e-2)" "unprognostic (1.04e-2)" "unprognostic (2.61e-1)" "unprognostic (6.25e-3)" "unprognostic (1.03e-2)" "unprognostic (2.40e-1)" "unprognostic (3.63e-3)" "unprognostic (8.10e-2)" "unprognostic (3.39e-1)" "unprognostic (3.36e-2)" "unprognostic (6.69e-3)" "unprognostic (1.48e-2)" "unprognostic (1.80e-1)" "unprognostic (1.60e-1)" "unprognostic (2.49e-1)" "unprognostic (1.08e-1)" "unprognostic (1.56e-1)" "unprognostic (2.27e-1)" "unprognostic (2.76e-1)" "unprognostic (2.58e-2)" "unprognostic (8.11e-2)" "unprognostic (9.52e-2)" "unprognostic (2.10e-1)" "unprognostic (1.72e-1)" ARID3A "BRIGHT, DRIL1" ENSG00000116017 "AT-rich interaction domain 3A" Q99856 19 925781-975939 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 22.0;testis: 16.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 291.4;Extravillous trophoblasts: 797.6;Hofbauer cells: 240.3;Migrating cytotrophoblasts: 352.7;Neutrophil progenitors: 180.2;Neutrophils: 326.1;pDCs: 246.7;Syncytiotrophoblasts: 783.4" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 133.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 6.3" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Pituitary gland - Somatotropes, Spleen - Mitotic cells (Spleen), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA004793, HPA076330" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 48: Non-specific - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 22 Nucleoplasm Cytosol "HPA004793: , HPA076330: " "unprognostic (3.07e-1)" "unprognostic (2.65e-2)" "unprognostic (4.90e-2)" "potential prognostic unfavorable (3.59e-6)" "unprognostic (3.38e-1)" "unprognostic (2.23e-3)" "unprognostic (1.72e-3)" "unprognostic (3.00e-1)" "unprognostic (1.99e-2)" "unprognostic (4.49e-3)" "unprognostic (2.73e-2)" "unprognostic (3.48e-1)" "unprognostic (2.12e-2)" "unprognostic (1.51e-2)" "unprognostic (2.53e-3)" "unprognostic (1.58e-1)" "unprognostic (1.69e-1)" "unprognostic (9.64e-2)" "unprognostic (1.04e-2)" "unprognostic (5.40e-2)" "unprognostic (1.39e-2)" "potential prognostic favorable (3.79e-4)" "potential prognostic unfavorable (8.53e-4)" "unprognostic (2.19e-2)" "unprognostic (9.79e-3)" "unprognostic (5.29e-2)" "unprognostic (1.62e-1)" "unprognostic (9.20e-2)" "unprognostic (5.04e-2)" "unprognostic (4.51e-2)" "unprognostic (1.95e-1)" ARID3B "BDP, DRIL2" ENSG00000179361 "AT-rich interaction domain 3B" Q8IVW6 15 74541206-74598131 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 23.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 140.8;Endometrial luminal cells: 125.9;Neutrophils: 168.3;pDCs: 114.1;Rod photoreceptor cells: 126.2;Syncytiotrophoblasts: 149.6" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 6 "Testicular Germ Cell Tumor (TCGA): 38.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "testis cancer: 87.9" "Stomach - Gastric mucous cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 7 "cerebellum: 41.4" HPA050320 Enhanced Supported Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 25: Non-specific - Transcription" "Cluster 34: Testis cancer - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 19 Nucleoplasm "HPA050320: " "unprognostic (1.97e-1)" "unprognostic (7.30e-2)" "unprognostic (3.34e-2)" "unprognostic (1.90e-1)" "unprognostic (2.37e-1)" "unprognostic (4.11e-2)" "unprognostic (6.24e-2)" "unprognostic (1.00e-1)" "unprognostic (3.43e-1)" "unprognostic (1.55e-1)" "unprognostic (6.10e-2)" "unprognostic (9.56e-2)" "unprognostic (1.46e-1)" "unprognostic (7.50e-3)" "potential prognostic unfavorable (1.54e-4)" "unprognostic (1.49e-1)" "unprognostic (1.98e-1)" "unprognostic (1.28e-1)" "potential prognostic favorable (1.66e-4)" "unprognostic (3.44e-2)" "unprognostic (8.85e-2)" "unprognostic (1.29e-2)" "unprognostic (1.37e-2)" "unprognostic (1.70e-1)" "unprognostic (4.19e-2)" "unprognostic (6.02e-3)" "unprognostic (4.71e-2)" "unprognostic (6.59e-2)" "unprognostic (1.54e-2)" "unprognostic (1.51e-3)" "unprognostic (1.13e-1)" ARID3C ENSG00000205143 "AT-rich interaction domain 3C" A6NKF2 9 34621049-34629066 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 27 "liver: 10.0" "Cell type enhanced" "Detected in some" "Gastric progenitor cells: 1.3;Hepatocytes: 4.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Liver Hepatocellular Carcinoma (TCGA): 2.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes, Skin - Inner root sheath cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 24: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 2 "unprognostic (3.09e-2)" "unprognostic (1.62e-2)" ARID4A "RBBP1, RBP-1, RBP1" ENSG00000032219 "AT-rich interaction domain 4A" P29374 14 58298504-58373887 "Predicted intracellular proteins, Transcription factors" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 421.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048899, HPA075572" Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 33 Nucleoplasm "Plasma membrane" "HPA048899: , HPA075572: " "unprognostic (3.24e-3)" "unprognostic (4.39e-1)" "unprognostic (5.49e-2)" "unprognostic (1.51e-1)" "unprognostic (2.01e-1)" "unprognostic (2.35e-1)" "unprognostic (6.92e-2)" "unprognostic (1.41e-3)" "potential prognostic favorable (8.06e-4)" "unprognostic (1.28e-2)" "validated prognostic favorable (1.24e-5)" "validated prognostic favorable (6.86e-5)" "unprognostic (1.00e-1)" "unprognostic (2.46e-1)" "unprognostic (1.71e-2)" "unprognostic (4.24e-2)" "unprognostic (6.71e-2)" "unprognostic (1.70e-1)" "unprognostic (2.11e-1)" "unprognostic (2.35e-1)" "potential prognostic unfavorable (1.22e-6)" "unprognostic (7.34e-2)" "unprognostic (5.98e-2)" "unprognostic (3.74e-2)" "unprognostic (1.07e-1)" "unprognostic (8.12e-2)" "unprognostic (1.26e-2)" "unprognostic (4.89e-1)" "unprognostic (2.91e-1)" "unprognostic (2.72e-2)" "unprognostic (9.98e-2)" ARID4B "BCAA, BRCAA1, RBP1L1, SAP180" ENSG00000054267 "AT-rich interaction domain 4B" Q4LE39 1 235131634-235328219 "Metabolic proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 2078.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027205, HPA027333" Approved Supported Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 61: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 47 "Mitochondria, Cytosol" Nucleoplasm "HPA027205: , HPA027333: " "unprognostic (1.52e-2)" "unprognostic (4.01e-3)" "unprognostic (5.46e-2)" "unprognostic (3.19e-2)" "unprognostic (2.91e-1)" "unprognostic (2.68e-1)" "unprognostic (3.83e-3)" "unprognostic (3.94e-2)" "unprognostic (7.36e-2)" "potential prognostic unfavorable (4.90e-4)" "potential prognostic favorable (2.44e-4)" "unprognostic (9.71e-3)" "unprognostic (1.68e-3)" "unprognostic (1.09e-1)" "unprognostic (3.83e-2)" "unprognostic (9.74e-2)" "unprognostic (6.72e-3)" "unprognostic (2.72e-1)" "unprognostic (1.57e-1)" "unprognostic (3.16e-1)" "unprognostic (1.57e-2)" "unprognostic (2.51e-2)" "unprognostic (2.66e-2)" "unprognostic (1.35e-1)" "unprognostic (3.58e-2)" "unprognostic (2.32e-1)" "unprognostic (1.59e-1)" "unprognostic (2.49e-2)" "unprognostic (2.81e-1)" "unprognostic (3.35e-2)" "unprognostic (1.22e-1)" ARID5A "MRF-1, RP11-363D14" ENSG00000196843 "AT-rich interaction domain 5A" Q03989 2 96536743-96552634 "Predicted intracellular proteins, Transcription factors" "Immunity, Innate immunity, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 78.7" "Cell type enhanced" "Detected in many" "Breast secretory cells: 208.7;Hofbauer cells: 114.5;Neutrophils: 220.3;Schwann cells: 128.1;Smooth muscle cells: 271.2;Vascular endothelial cells: 136.3;Vascular smooth muscle cells: 140.5" "Group enriched" "Detected in many" 6 "central nervous system macrophage: 43.9;endothelial cell: 94.1;leukocyte: 43.1;pericyte: 40.6;vascular associated smooth muscle cell: 93.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Leukemia: 22.6;lymphoma: 38.9;Myeloma: 47.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002860, HPA023879" Approved Supported Nucleoplasm,Nucleoli NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 103: Non-specific - Basic cellular processes" 100 Nucleoplasm Nucleoli "HPA002860: , HPA023879: " "unprognostic (2.04e-2)" "potential prognostic favorable (4.04e-4)" "unprognostic (3.42e-2)" "unprognostic (8.81e-2)" "unprognostic (9.63e-2)" "unprognostic (4.46e-2)" "unprognostic (3.12e-2)" "unprognostic (3.15e-1)" "unprognostic (2.52e-1)" "unprognostic (2.43e-1)" "unprognostic (3.15e-1)" "unprognostic (2.22e-2)" "unprognostic (3.32e-2)" "unprognostic (1.80e-1)" "unprognostic (2.80e-1)" "unprognostic (4.87e-2)" "unprognostic (2.14e-1)" "unprognostic (1.73e-2)" "unprognostic (8.14e-2)" "unprognostic (1.37e-1)" "unprognostic (4.77e-2)" "unprognostic (1.06e-2)" "unprognostic (5.14e-2)" "unprognostic (3.79e-2)" "unprognostic (4.44e-2)" "unprognostic (2.56e-2)" "unprognostic (1.32e-2)" "unprognostic (3.79e-2)" "unprognostic (3.98e-2)" "unprognostic (2.64e-2)" "unprognostic (1.30e-2)" ARID5B "FLJ21150, MRF2" ENSG00000150347 "AT-rich interaction domain 5B" Q14865 10 61901684-62096944 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 83.9" "Cell type enhanced" "Detected in many" "B-cells: 978.9;Basal keratinocytes: 1080.7;Endometrial glandular cells: 1191.1;Smooth muscle cells: 969.6;Syncytiotrophoblasts: 1516.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015037 Uncertain Approved "Nucleoplasm,Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 14 "Endoplasmic reticulum" "Nucleoplasm, Plasma membrane, Cytosol" "HPA015037: " "unprognostic (2.24e-3)" "unprognostic (2.23e-1)" "unprognostic (2.12e-2)" "unprognostic (9.26e-2)" "unprognostic (2.34e-1)" "unprognostic (2.36e-2)" "unprognostic (2.20e-1)" "unprognostic (6.97e-2)" "unprognostic (7.46e-3)" "unprognostic (3.59e-1)" "validated prognostic favorable (3.52e-9)" "validated prognostic favorable (7.96e-4)" "unprognostic (1.40e-1)" "unprognostic (7.02e-3)" "unprognostic (4.59e-2)" "unprognostic (2.76e-2)" "unprognostic (4.72e-2)" "unprognostic (4.38e-1)" "unprognostic (9.23e-2)" "unprognostic (1.87e-2)" "unprognostic (4.86e-3)" "unprognostic (1.82e-1)" "unprognostic (2.09e-1)" "unprognostic (2.56e-1)" "unprognostic (9.52e-2)" "unprognostic (3.20e-2)" "unprognostic (9.97e-2)" "unprognostic (1.80e-1)" "unprognostic (3.44e-2)" "unprognostic (9.16e-2)" "unprognostic (6.19e-2)" ARIH1 "ARI, HARI, HHARI, UBCH7BP" ENSG00000166233 "Ariadne RBR E3 ubiquitin protein ligase 1" Q9Y4X5 15 72474330-72602987 "Disease related genes, Enzymes, Essential proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 44.9;testis: 39.7" "Cell type enhanced" "Detected in all" "Neutrophils: 2015.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003295, HPA073245" Approved Supported Nucleoplasm NA NA "Cluster 32: Basophils - Transcription" "Cluster 47: Testis - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 61: BICR 18 - Protein kinases" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 54 Nucleoplasm "HPA003295: , HPA073245: " "unprognostic (2.53e-1)" "unprognostic (1.02e-1)" "unprognostic (5.51e-2)" "unprognostic (5.50e-2)" "unprognostic (4.04e-1)" "unprognostic (4.47e-3)" "unprognostic (1.31e-1)" "unprognostic (6.64e-3)" "unprognostic (3.47e-2)" "potential prognostic unfavorable (9.80e-4)" "validated prognostic favorable (1.26e-4)" "validated prognostic favorable (3.87e-4)" "unprognostic (1.06e-1)" "unprognostic (6.30e-2)" "unprognostic (1.06e-1)" "unprognostic (2.65e-1)" "unprognostic (2.88e-3)" "unprognostic (1.72e-1)" "unprognostic (7.71e-2)" "unprognostic (2.48e-3)" "unprognostic (5.07e-2)" "unprognostic (1.93e-2)" "unprognostic (6.40e-3)" "unprognostic (2.92e-3)" "unprognostic (8.94e-3)" "unprognostic (2.13e-1)" "unprognostic (2.34e-2)" "unprognostic (1.24e-1)" "unprognostic (2.33e-1)" "unprognostic (6.00e-2)" "unprognostic (2.02e-1)" ARIH2 TRIAD1 ENSG00000177479 "Ariadne RBR E3 ubiquitin protein ligase 2" O95376 3 48918821-48986382 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067381, HPA069715, HPA070963" Enhanced Nucleoplasm NA NA "Cluster 41: Basophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 55: Myocytes - Oxidative muscle function" 48 Nucleoplasm "HPA067381: , HPA069715: , HPA070963: " "unprognostic (1.11e-1)" "unprognostic (1.69e-1)" "unprognostic (3.36e-1)" "unprognostic (2.38e-3)" "unprognostic (2.35e-1)" "unprognostic (3.67e-2)" "unprognostic (7.44e-2)" "unprognostic (2.52e-2)" "unprognostic (2.07e-1)" "unprognostic (1.52e-3)" "unprognostic (5.30e-3)" "unprognostic (4.13e-2)" "unprognostic (8.60e-3)" "potential prognostic unfavorable (1.08e-4)" "unprognostic (7.25e-3)" "unprognostic (1.19e-1)" "unprognostic (5.25e-2)" "unprognostic (5.71e-2)" "unprognostic (3.94e-2)" "unprognostic (8.55e-2)" "unprognostic (4.91e-2)" "unprognostic (2.37e-2)" "unprognostic (8.36e-2)" "unprognostic (1.10e-1)" "unprognostic (8.90e-2)" "unprognostic (8.09e-2)" "unprognostic (6.59e-2)" "unprognostic (1.11e-1)" "unprognostic (5.66e-1)" "unprognostic (2.45e-2)" "unprognostic (3.03e-2)" ARL1 ARFL1 ENSG00000120805 "ADP ribosylation factor like GTPase 1" P40616 12 101393116-101407772 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 325.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Minor Salivary Gland - Minor salivary glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062656, HPA073012" Approved Supported "Golgi apparatus" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 38: Non-specific - Transcription" "Cluster 8: Non-specific - Secretory pathway" 25 "Golgi apparatus" "HPA062656: , HPA073012: " "unprognostic (1.79e-2)" "unprognostic (5.05e-2)" "unprognostic (9.62e-2)" "unprognostic (2.27e-1)" "unprognostic (4.75e-2)" "unprognostic (2.58e-2)" "unprognostic (5.37e-3)" "potential prognostic unfavorable (9.22e-6)" "unprognostic (4.89e-2)" "unprognostic (1.91e-3)" "potential prognostic favorable (7.81e-7)" "unprognostic (2.78e-1)" "unprognostic (5.39e-3)" "validated prognostic unfavorable (3.86e-4)" "validated prognostic unfavorable (8.16e-4)" "unprognostic (1.59e-1)" "unprognostic (1.67e-1)" "unprognostic (3.62e-1)" "unprognostic (4.25e-1)" "unprognostic (4.08e-1)" "unprognostic (7.60e-3)" "unprognostic (1.73e-1)" "unprognostic (3.26e-2)" "unprognostic (1.00e-1)" "unprognostic (1.79e-1)" "unprognostic (1.82e-3)" "unprognostic (1.28e-1)" "unprognostic (1.79e-1)" "unprognostic (1.08e-1)" "unprognostic (9.63e-2)" "unprognostic (1.85e-1)" ARL10 ARL10A ENSG00000175414 "ADP ribosylation factor like GTPase 10" Q8N8L6 5 176365487-176401865 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 142.8;Epicardial cells: 206.9" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 14.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047044 Approved NA NA "Cluster 34: B-cells - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 1 "HPA047044: " "unprognostic (1.15e-1)" "unprognostic (1.11e-1)" "unprognostic (9.46e-2)" "unprognostic (2.17e-2)" "unprognostic (3.05e-2)" "unprognostic (3.01e-2)" "unprognostic (5.43e-1)" "unprognostic (1.93e-1)" "unprognostic (1.09e-1)" "unprognostic (1.53e-2)" "unprognostic (2.57e-3)" "unprognostic (3.24e-2)" "potential prognostic favorable (5.46e-4)" "unprognostic (1.23e-2)" "unprognostic (2.46e-2)" "unprognostic (2.73e-1)" "unprognostic (1.50e-1)" "unprognostic (6.40e-2)" "potential prognostic unfavorable (6.26e-5)" "unprognostic (2.10e-2)" "unprognostic (8.93e-3)" "potential prognostic unfavorable (7.05e-5)" "unprognostic (2.17e-2)" "unprognostic (2.96e-2)" "unprognostic (4.72e-2)" "unprognostic (1.73e-1)" "unprognostic (1.46e-1)" "unprognostic (2.82e-3)" "unprognostic (1.12e-1)" ARL11 "ARLTS1, FLJ33930" ENSG00000152213 "ADP ribosylation factor like GTPase 11" Q969Q4 13 49628507-49633872 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 6.4" "Cell type enhanced" "Detected in many" "B-cells: 19.0;Hematopoietic stem cells: 17.5;Hofbauer cells: 45.4;Kupffer cells: 45.1;Macrophages: 22.2;Mast cells: 16.8;Microglia: 26.7;Monocyte progenitors: 26.0;monocytes: 26.0;Neutrophil progenitors: 40.2;Neutrophils: 123.6" "Cell type enriched" "Detected in some" 7 "central nervous system macrophage: 31.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 37.9" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 7 "Leukemia: 12.2;lymphoma: 8.8" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA040855, HPA040887" Uncertain Approved "Intermediate filaments,Cytosol" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 6: Leukemia - Signal transduction" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 5 "Intermediate filaments, Cytosol" "HPA040855: , HPA040887: " "unprognostic (9.32e-2)" "unprognostic (1.09e-2)" "unprognostic (1.39e-1)" "unprognostic (4.16e-2)" "unprognostic (3.65e-2)" "unprognostic (1.65e-2)" "unprognostic (7.63e-2)" "unprognostic (2.79e-1)" "unprognostic (1.04e-1)" "unprognostic (2.14e-1)" "unprognostic (3.83e-2)" "unprognostic (2.48e-1)" "unprognostic (9.59e-2)" "unprognostic (2.36e-2)" "unprognostic (7.53e-2)" "unprognostic (4.22e-2)" "unprognostic (2.06e-2)" "unprognostic (5.52e-2)" "unprognostic (1.94e-2)" "unprognostic (1.78e-1)" "unprognostic (2.13e-1)" "unprognostic (7.72e-3)" "unprognostic (2.15e-2)" "unprognostic (3.77e-1)" "unprognostic (4.19e-2)" ARL13A ARL13 ENSG00000174225 "ADP ribosylation factor like GTPase 13A" Q5H913 X 100969708-100990831 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "testis: 4.8" "Group enriched" "Detected in some" 7 "Early spermatids: 72.6;Late primary spermatocytes: 37.5;Late spermatids: 88.9" "Low cell type specificity" "Detected in some" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA037377, HPA037378" Uncertain Approved "Plasma membrane,Actin filaments,Cytosol,Acrosome,Connecting piece,Mid piece,Principal piece" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 36: Non-specific - mRNA processing" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" "Plasma membrane, Actin filaments, Connecting piece, Mid piece" "Cytosol, Acrosome, Principal piece" "HPA037377: , HPA037378: " "unprognostic (3.82e-1)" "unprognostic (5.50e-2)" ARL13B "ARL2L1, DKFZp761H079, JBTS8" ENSG00000169379 "ADP ribosylation factor like GTPase 13B" Q3SXY8 3 93980139-94055678 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant, Joubert syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 16.8" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 317.4;Cone photoreceptor cells: 240.1;Rod photoreceptor cells: 611.1" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 331.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048926 Approved Supported "Microtubules,Cytokinetic bridge,Primary cilium,Primary cilium transition zone,Basal body,Acrosome,Equatorial segment,Mid piece,Principal piece,End piece" Yes NA "Cluster 14: Non-specific - Unknown function" "Cluster 42: Retina - Visual perception" "Cluster 8: Immune cells - Immune response" "Cluster 3: Rhabdoid - Membrane components" "Cluster 79: Photoreceptor cells - Phototransduction" 127 "Microtubules, Primary cilium, Primary cilium transition zone" "Cytokinetic bridge, Basal body, Acrosome, Equatorial segment, Mid piece, Principal piece, End piece" "HPA048926: " "unprognostic (8.35e-2)" "unprognostic (1.37e-1)" "unprognostic (3.58e-1)" "unprognostic (1.37e-1)" "unprognostic (3.34e-1)" "unprognostic (3.48e-1)" "unprognostic (1.76e-1)" "unprognostic (1.16e-1)" "unprognostic (1.01e-1)" "potential prognostic unfavorable (6.28e-4)" "potential prognostic favorable (5.08e-5)" "unprognostic (2.21e-1)" "unprognostic (3.00e-2)" "unprognostic (5.47e-2)" "unprognostic (1.68e-1)" "unprognostic (1.82e-1)" "unprognostic (3.26e-1)" "unprognostic (4.20e-2)" "unprognostic (6.73e-2)" "unprognostic (8.04e-3)" "unprognostic (4.45e-3)" "unprognostic (3.90e-3)" "unprognostic (6.68e-2)" "unprognostic (3.49e-1)" "unprognostic (1.42e-2)" "unprognostic (1.35e-1)" "unprognostic (7.18e-2)" "unprognostic (1.01e-1)" "unprognostic (4.44e-2)" "unprognostic (4.58e-2)" ARL14 "ARF7, FLJ22595" ENSG00000179674 "ADP ribosylation factor like GTPase 14" Q8N4G2 3 160677160-160678448 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "gallbladder: 120.8;intestine: 48.2;stomach 1: 72.9" "Cell type enhanced" "Detected in some" "Colonocytes: 352.8;Enteric stem cells: 65.0;Enteric transient amplifying cells: 83.5;Enterocytes: 165.7;Foveolar cells: 261.5;Gastric progenitor cells: 55.1;Goblet cells: 147.3;Neuroendocrine cells: 55.6;Urothelial cells: 273.6" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Pancreatic Adenocarcinoma (TCGA): 40.7" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 15 "memory B-cell: 1.8" "Lineage enriched" "Detected in single" 18 "B-cells: 1.8" "Cancer enhanced" "Detected in many" "pancreatic cancer: 19.7" "Colon - Colon enterocytes, Prostate - Urothelial cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 17: Intestine - Digestion" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 3 "unprognostic (4.24e-2)" "unprognostic (4.27e-3)" "unprognostic (7.68e-2)" "unprognostic (4.79e-2)" "unprognostic (6.56e-2)" "unprognostic (9.97e-2)" "unprognostic (1.76e-1)" "unprognostic (5.63e-3)" "unprognostic (1.24e-3)" "unprognostic (2.93e-2)" "potential prognostic unfavorable (1.17e-7)" "unprognostic (6.98e-2)" "unprognostic (2.16e-3)" "unprognostic (1.01e-3)" "potential prognostic unfavorable (7.97e-4)" "unprognostic (6.82e-2)" "unprognostic (2.85e-3)" "unprognostic (1.55e-1)" "unprognostic (2.73e-1)" ARL14EP "ARF7EP, C11orf46, FLJ38968" ENSG00000152219 "ADP ribosylation factor like GTPase 14 effector protein" Q8N8R7 11 30323104-30338223 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 206.1;Oocytes: 128.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039634, HPA048127" Approved Approved "Nucleoplasm,Nucleoli,Vesicles,Plasma membrane,Focal adhesion sites,Cytosol" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 27 "Vesicles, Focal adhesion sites, Cytosol" "Nucleoplasm, Nucleoli, Plasma membrane" "HPA039634: , HPA048127: " "unprognostic (1.19e-1)" "unprognostic (2.89e-2)" "unprognostic (2.24e-1)" "unprognostic (1.01e-1)" "unprognostic (1.92e-1)" "unprognostic (1.87e-1)" "unprognostic (4.84e-2)" "unprognostic (1.77e-1)" "unprognostic (5.08e-2)" "validated prognostic favorable (3.30e-6)" "validated prognostic favorable (2.58e-4)" "unprognostic (8.31e-2)" "unprognostic (3.03e-3)" "unprognostic (6.31e-2)" "unprognostic (1.26e-1)" "unprognostic (6.49e-2)" "unprognostic (1.36e-1)" "unprognostic (1.01e-1)" "unprognostic (1.06e-2)" "unprognostic (2.90e-1)" "unprognostic (2.98e-2)" "unprognostic (1.07e-1)" "potential prognostic favorable (8.75e-4)" "unprognostic (4.95e-1)" "unprognostic (9.59e-2)" "unprognostic (1.47e-1)" "unprognostic (1.59e-1)" "unprognostic (9.40e-2)" "unprognostic (2.15e-2)" ARL14EPL ENSG00000268223 "ADP ribosylation factor like GTPase 14 effector protein like" P0DKL9 5 116032324-116060118 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "B-cells: 3.0;Cardiomyocytes: 4.4;Early spermatids: 5.5;Endometrial ciliated cells: 3.2;Gastric chief cells: 5.5;Mucous neck cells: 3.5;Papillary tip epithelial cells: 2.7;Parietal cells: 7.1;Renal collecting duct principal cells: 3.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 7.0;lymphoma: 6.6" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" ARL15 "ARFRP2, FLJ20051" ENSG00000185305 "ADP ribosylation factor like GTPase 15" Q9NXU5 5 53883942-54310582 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 1518.6;Renal collecting duct intercalated cells: 2219.9;Renal connecting tubule cells: 3279.9;Sertoli cells: 2305.2;Vascular endothelial cells: 1393.6" "Cell type enhanced" "Detected in all" "endothelial cell: 3123.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Prostate - Endothelial cells, Skin - Outer root sheath cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044604 Uncertain Approved "Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Basal body" Yes NA "Cluster 28: Neutrophils - Unknown function" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 51: Neurons - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 17 "Microtubules, Primary cilium" "Cytokinetic bridge, Mitotic spindle, Basal body" "HPA044604: " "unprognostic (6.37e-2)" "unprognostic (3.63e-1)" "unprognostic (1.80e-2)" "unprognostic (2.46e-3)" "unprognostic (1.84e-2)" "unprognostic (4.34e-2)" "unprognostic (3.02e-1)" "unprognostic (5.04e-2)" "unprognostic (1.09e-1)" "unprognostic (5.71e-2)" "potential prognostic favorable (2.64e-10)" "unprognostic (2.76e-3)" "unprognostic (3.15e-1)" "unprognostic (3.04e-2)" "unprognostic (9.33e-2)" "unprognostic (4.74e-1)" "unprognostic (5.52e-1)" "unprognostic (5.24e-2)" "unprognostic (1.24e-1)" "unprognostic (8.89e-2)" "potential prognostic unfavorable (1.36e-4)" "unprognostic (2.53e-3)" "unprognostic (2.54e-1)" "unprognostic (3.21e-1)" "unprognostic (1.05e-1)" "unprognostic (2.15e-1)" "unprognostic (5.48e-3)" "unprognostic (1.54e-1)" "unprognostic (2.18e-1)" "unprognostic (7.00e-3)" "unprognostic (5.09e-2)" ARL16 ENSG00000214087 "ADP ribosylation factor like GTPase 16" 17 81681187-81683797 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043711 Uncertain Approved "Primary cilium,Basal body" NA NA "Cluster 32: Basophils - Transcription" "Cluster 74: Non-specific - Signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 97: Non-specific - Cellular respiration" "Primary cilium, Basal body" "HPA043711: " "unprognostic (2.82e-2)" "unprognostic (1.02e-1)" "unprognostic (3.47e-1)" "unprognostic (1.12e-1)" "unprognostic (4.60e-1)" "unprognostic (4.67e-2)" "unprognostic (1.41e-1)" "unprognostic (8.40e-2)" "unprognostic (9.61e-2)" "unprognostic (1.50e-3)" "potential prognostic favorable (3.34e-4)" "unprognostic (5.72e-3)" "unprognostic (8.78e-3)" "unprognostic (1.80e-3)" "unprognostic (1.14e-1)" "unprognostic (2.35e-1)" "unprognostic (2.08e-1)" "unprognostic (3.95e-2)" "unprognostic (7.95e-2)" "unprognostic (1.39e-1)" "unprognostic (6.07e-3)" "unprognostic (1.75e-1)" "unprognostic (3.29e-3)" "unprognostic (9.67e-3)" "unprognostic (4.59e-1)" "unprognostic (1.56e-2)" "potential prognostic unfavorable (9.58e-6)" "unprognostic (9.86e-2)" "unprognostic (1.35e-1)" "unprognostic (1.90e-1)" "unprognostic (1.43e-1)" ARL17A "ARF1P2, ARL17P1" ENSG00000185829 "ADP ribosylation factor like GTPase 17A" Q8IVW1 17 46499780-46579695 "Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bergmann glia: 22.9;Brain excitatory neurons: 22.5;Choroid plexus epithelial cells: 22.3;Distal convoluted tubule cells: 52.0;Loop of henle epithelial cells: 38.2;Microglia: 31.9;Oligodendrocyte progenitor cells: 23.6;Oligodendrocytes: 24.4;Papillary tip epithelial cells: 35.6;Podocytes: 28.1;Proximal tubule cells: 29.0;Renal collecting duct intercalated cells: 41.8;Renal collecting duct principal cells: 38.5;Renal connecting tubule cells: 40.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA046814, HPA047080" Uncertain Supported Nucleoplasm NA NA "Cluster 32: Basophils - Transcription" "Cluster 22: Epididymis - Mixed function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 27: Breast cancer - Unknown function" "Cluster 102: Non-specific - Mixed function" Nucleoplasm "HPA046814: , HPA047080: " "unprognostic (4.60e-2)" "unprognostic (3.90e-2)" "unprognostic (4.17e-2)" "unprognostic (3.28e-2)" "unprognostic (4.07e-2)" "unprognostic (1.02e-1)" "unprognostic (1.39e-1)" "unprognostic (2.95e-1)" "unprognostic (9.99e-2)" "unprognostic (2.24e-2)" "unprognostic (4.23e-2)" "unprognostic (7.41e-3)" "unprognostic (3.94e-2)" "unprognostic (2.03e-2)" "unprognostic (4.79e-1)" "unprognostic (1.93e-1)" "unprognostic (2.08e-1)" "unprognostic (1.01e-1)" "unprognostic (1.23e-1)" "unprognostic (9.92e-2)" "unprognostic (2.19e-2)" "unprognostic (1.32e-2)" "unprognostic (2.70e-2)" "potential prognostic favorable (1.00e-4)" "unprognostic (8.68e-3)" "unprognostic (1.02e-1)" "unprognostic (1.20e-1)" "unprognostic (3.75e-1)" "unprognostic (1.81e-1)" "unprognostic (3.45e-2)" ARL17B ARL17 ENSG00000228696 "ADP ribosylation factor like GTPase 17B" Q8IVW1 17 46274784-46361766 "Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 169.8;Bergmann glia: 121.3;Brain excitatory neurons: 130.7;Brain inhibitory neurons: 145.5;Choroid plexus epithelial cells: 365.4;Distal convoluted tubule cells: 76.9;Ependymal cells: 223.8;Loop of henle epithelial cells: 131.4;Microglia: 155.1;Oligodendrocyte progenitor cells: 176.3;Oligodendrocytes: 213.2;Other brain neurons: 104.6;Papillary tip epithelial cells: 109.1;Renal collecting duct principal cells: 136.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" HPA046814 Uncertain Approved Nucleoplasm NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 49: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 102: Non-specific - Mixed function" Nucleoplasm "HPA046814: " "unprognostic (7.76e-2)" "unprognostic (2.52e-1)" "unprognostic (5.75e-2)" "unprognostic (2.84e-1)" "unprognostic (1.62e-2)" "unprognostic (1.28e-1)" "unprognostic (2.93e-1)" "unprognostic (8.53e-2)" "unprognostic (9.48e-2)" "unprognostic (2.99e-1)" "unprognostic (7.90e-2)" "unprognostic (3.61e-2)" "unprognostic (3.37e-1)" "unprognostic (3.37e-2)" "unprognostic (6.08e-2)" "unprognostic (7.27e-2)" "unprognostic (2.48e-2)" "unprognostic (6.64e-2)" "unprognostic (1.85e-2)" "unprognostic (1.15e-1)" "unprognostic (2.80e-1)" "unprognostic (2.01e-1)" "potential prognostic unfavorable (7.18e-4)" "unprognostic (1.86e-1)" "unprognostic (2.63e-2)" "unprognostic (5.33e-2)" "unprognostic (1.20e-1)" "unprognostic (2.05e-1)" "unprognostic (1.74e-1)" "unprognostic (1.07e-1)" "unprognostic (1.48e-1)" ARL2 ARFL2 ENSG00000213465 "ADP ribosylation factor like GTPase 2" P36404 11 65014160-65022184 "Disease related genes, Essential proteins, Predicted intracellular proteins" "Cell cycle" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 77.4;Late spermatids: 290.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044610 Supported Approved "Nucleoplasm,Nucleoli,Mitochondria,Basal body,Equatorial segment,Flagellar centriole,Mid piece" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" 35 "Nucleoplasm, Basal body, Flagellar centriole" "Nucleoli, Mitochondria, Equatorial segment, Mid piece" "HPA044610: " "unprognostic (6.74e-2)" "unprognostic (6.35e-2)" "unprognostic (1.70e-1)" "unprognostic (2.08e-1)" "unprognostic (1.25e-1)" "unprognostic (3.61e-1)" "unprognostic (2.14e-1)" "unprognostic (2.97e-1)" "unprognostic (3.08e-2)" "unprognostic (3.09e-1)" "unprognostic (3.77e-1)" "unprognostic (3.86e-1)" "unprognostic (1.10e-2)" "potential prognostic unfavorable (8.61e-4)" "unprognostic (1.10e-2)" "unprognostic (9.31e-2)" "unprognostic (9.42e-2)" "unprognostic (1.82e-1)" "unprognostic (1.55e-1)" "unprognostic (5.47e-2)" "unprognostic (1.18e-1)" "unprognostic (3.20e-2)" "unprognostic (2.70e-2)" "potential prognostic favorable (6.83e-4)" "unprognostic (2.66e-1)" "unprognostic (2.81e-1)" "unprognostic (9.61e-2)" "unprognostic (3.41e-1)" "unprognostic (2.75e-1)" "unprognostic (2.11e-1)" "unprognostic (5.57e-2)" ARL2BP "BART, BART1, RP66" ENSG00000102931 "ADP ribosylation factor like GTPase 2 binding protein" Q9Y2Y0 16 57245259-57253635 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 318.4;Esophageal apical cells: 216.1;Late spermatids: 811.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043066, HPA048440" Approved Supported "Nucleoplasm,Centrosome,Basal body,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 18 "Nucleoplasm, Cytosol" "Centrosome, Basal body" "HPA043066: , HPA048440: " "unprognostic (1.45e-2)" "unprognostic (1.29e-2)" "unprognostic (2.41e-1)" "unprognostic (1.25e-1)" "unprognostic (2.16e-1)" "unprognostic (7.67e-3)" "unprognostic (5.16e-2)" "unprognostic (1.83e-1)" "unprognostic (2.62e-3)" "unprognostic (2.09e-1)" "potential prognostic favorable (1.78e-5)" "unprognostic (1.41e-1)" "unprognostic (3.92e-1)" "unprognostic (1.38e-2)" "unprognostic (6.70e-2)" "unprognostic (2.62e-3)" "unprognostic (1.88e-2)" "unprognostic (2.05e-2)" "unprognostic (1.20e-1)" "unprognostic (3.18e-1)" "unprognostic (1.27e-2)" "unprognostic (3.94e-2)" "unprognostic (1.12e-1)" "unprognostic (5.36e-2)" "unprognostic (1.12e-1)" "unprognostic (2.75e-2)" "unprognostic (5.44e-2)" "unprognostic (4.55e-3)" "unprognostic (2.62e-1)" "unprognostic (7.61e-3)" "unprognostic (3.20e-1)" ARL3 ARFL3 ENSG00000138175 "ADP ribosylation factor like GTPase 3" P36405 10 102673731-102714397 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Protein transport, Transport" "Ciliopathy, Disease variant, Joubert syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 89.3" "Cell type enhanced" "Detected in many" "Epididymal efferent duct ciliated cells: 280.4;Fallopian tube ciliated cells: 402.8;Respiratory ciliated cells: 306.0;Rod photoreceptor cells: 382.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Fibroblasts_1, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036292, HPA063596" Approved Supported "Nucleoplasm,Primary cilium,Centrosome,Basal body" NA NA 14000 "Cluster 4: Neutrophils - Degranulation" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 52: Non-specific - Mitochondria" "Cluster 79: Photoreceptor cells - Phototransduction" 42 "Nucleoplasm, Centrosome, Basal body" "Primary cilium" "HPA036292: , HPA063596: " "unprognostic (2.20e-1)" "unprognostic (1.35e-1)" "unprognostic (1.36e-2)" "potential prognostic favorable (9.09e-4)" "unprognostic (6.81e-2)" "unprognostic (1.65e-1)" "unprognostic (1.15e-1)" "unprognostic (6.12e-3)" "unprognostic (3.86e-2)" "unprognostic (2.85e-1)" "potential prognostic favorable (3.95e-6)" "unprognostic (2.17e-2)" "unprognostic (1.18e-3)" "unprognostic (4.66e-3)" "unprognostic (2.31e-2)" "unprognostic (1.44e-1)" "unprognostic (1.27e-1)" "unprognostic (1.79e-2)" "unprognostic (4.90e-2)" "unprognostic (2.32e-1)" "unprognostic (1.14e-2)" "unprognostic (1.26e-1)" "unprognostic (5.20e-3)" "unprognostic (5.43e-2)" "unprognostic (1.77e-1)" "unprognostic (3.12e-2)" "unprognostic (1.21e-1)" "unprognostic (1.64e-2)" "unprognostic (1.34e-2)" "unprognostic (9.14e-2)" "unprognostic (4.12e-2)" ARL4A ARL4 ENSG00000122644 "ADP ribosylation factor like GTPase 4A" P40617 7 12686856-12690958 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 181.2" "Cell type enriched" "Detected in many" 4 "Late spermatids: 6441.7" "Cell type enhanced" "Detected in all" "cerebellar inhibitory: 86.7;endothelial cell: 148.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064513 Approved Nucleoplasm,Cytosol NA Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 39: Testis - Nuclear processes" "Cluster 53: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 9 "Nucleoplasm, Cytosol" "HPA064513: " "unprognostic (1.40e-2)" "unprognostic (2.63e-1)" "unprognostic (1.87e-2)" "unprognostic (1.10e-1)" "unprognostic (5.49e-2)" "unprognostic (7.79e-2)" "unprognostic (8.33e-2)" "unprognostic (1.53e-2)" "unprognostic (2.04e-1)" "unprognostic (1.18e-1)" "unprognostic (9.46e-3)" "unprognostic (2.54e-1)" "unprognostic (1.50e-2)" "unprognostic (4.43e-3)" "unprognostic (2.01e-2)" "unprognostic (3.43e-2)" "unprognostic (5.01e-3)" "unprognostic (1.61e-1)" "unprognostic (2.54e-1)" "unprognostic (2.87e-1)" "unprognostic (8.42e-2)" "unprognostic (8.81e-3)" "unprognostic (2.88e-3)" "unprognostic (1.79e-2)" "unprognostic (5.78e-2)" "unprognostic (1.51e-1)" "unprognostic (2.87e-1)" "unprognostic (1.14e-1)" "unprognostic (2.16e-1)" "unprognostic (1.14e-3)" "unprognostic (3.09e-1)" ARL4C "ARL7, LAK" ENSG00000188042 "ADP ribosylation factor like GTPase 4C" P56559 2 234493041-234497081 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 61.3;lymphoid tissue: 68.9" "Cell type enhanced" "Detected in many" "cDC: 308.9;Endometrial luminal cells: 266.3;Innate lymphoid cells: 186.0;Kupffer cells: 423.3;Macrophages: 271.9;Mast cells: 220.3;NK-cells: 439.9;pDCs: 322.8;T-cells: 323.8" "Cell type enhanced" "Detected in many" "CGE interneuron: 271.4;LAMP5-LHX6 and Chandelier: 266.9;leukocyte: 245.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney cancer: 169.9" "Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028927 Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 8 "Plasma membrane" Cytosol "HPA028927: " "unprognostic (2.68e-1)" "unprognostic (6.04e-2)" "unprognostic (8.23e-2)" "unprognostic (7.95e-2)" "unprognostic (9.99e-3)" "unprognostic (6.66e-2)" "unprognostic (1.26e-2)" "potential prognostic unfavorable (3.00e-4)" "unprognostic (9.28e-2)" "unprognostic (3.31e-2)" "potential prognostic unfavorable (6.03e-4)" "unprognostic (2.23e-3)" "unprognostic (1.13e-3)" "unprognostic (9.08e-2)" "unprognostic (9.89e-2)" "unprognostic (1.71e-2)" "unprognostic (1.95e-3)" "unprognostic (1.32e-1)" "unprognostic (9.03e-2)" "unprognostic (9.59e-3)" "unprognostic (1.98e-1)" "unprognostic (4.33e-3)" "unprognostic (9.73e-3)" "unprognostic (1.30e-1)" "unprognostic (1.33e-3)" "unprognostic (2.05e-2)" "unprognostic (4.24e-1)" "unprognostic (7.00e-2)" "unprognostic (6.47e-2)" "unprognostic (6.22e-2)" "unprognostic (1.00e-1)" ARL4D ARF4L ENSG00000175906 "ADP ribosylation factor like GTPase 4D" P49703 17 43398993-43401137 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 154.6;Decidual stromal cells: 153.8;Early spermatids: 263.4;Esophageal apical cells: 321.5;Esophageal basal cells: 198.1;Esophageal suprabasal cells: 411.6;Ocular epithelial cells: 483.2;Rod photoreceptor cells: 326.4;Suprabasal keratinocytes: 192.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 32.4;naive B-cell: 36.3" "Lineage enriched" "Detected in all" 4 "B-cells: 36.3" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Minor Salivary Gland - Minor salivary gland basal cells, Skin - Keratinocyte (other), Stomach - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basal ganglia: 11.4;cerebral cortex: 11.5;hippocampal formation: 7.5;olfactory bulb: 5.6;spinal cord: 7.1" HPA060379 Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 31: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 100: Stratified epithelial cells - Barrier functions" 21 Vesicles "Golgi apparatus" "HPA060379: " "potential prognostic unfavorable (1.52e-4)" "unprognostic (2.53e-2)" "unprognostic (4.04e-2)" "unprognostic (9.07e-2)" "unprognostic (1.88e-2)" "unprognostic (1.91e-1)" "unprognostic (6.23e-2)" "unprognostic (5.02e-2)" "unprognostic (1.99e-3)" "unprognostic (3.11e-1)" "unprognostic (1.24e-3)" "unprognostic (1.23e-2)" "unprognostic (1.82e-1)" "unprognostic (2.46e-1)" "unprognostic (4.56e-3)" "potential prognostic unfavorable (1.68e-4)" "unprognostic (2.53e-1)" "unprognostic (4.64e-2)" "unprognostic (9.65e-2)" "unprognostic (1.31e-1)" "unprognostic (4.40e-1)" "unprognostic (1.76e-2)" "unprognostic (6.07e-2)" "unprognostic (2.56e-1)" "unprognostic (5.74e-3)" "unprognostic (7.88e-2)" "unprognostic (8.30e-2)" "unprognostic (4.43e-2)" "unprognostic (5.63e-2)" "potential prognostic unfavorable (4.04e-4)" "unprognostic (2.08e-3)" ARL5A ARL5 ENSG00000162980 "ADP ribosylation factor like GTPase 5A" Q9Y689 2 151788984-151828492 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglia: 284.5" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 369.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 6 "basophil: 88.6" "Lineage enriched" "Detected in all" 6 "granulocytes: 88.6" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027002 Approved NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 21: Non-specific - Metabolism" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 2 "HPA027002: " "unprognostic (4.93e-1)" "unprognostic (2.65e-3)" "unprognostic (6.70e-2)" "unprognostic (4.92e-3)" "unprognostic (1.05e-1)" "unprognostic (1.89e-1)" "unprognostic (2.04e-1)" "unprognostic (2.12e-1)" "unprognostic (7.26e-2)" "unprognostic (2.70e-1)" "potential prognostic favorable (9.23e-10)" "unprognostic (4.84e-3)" "unprognostic (1.30e-1)" "unprognostic (9.82e-2)" "unprognostic (1.36e-1)" "unprognostic (1.05e-1)" "unprognostic (1.72e-1)" "unprognostic (9.60e-2)" "unprognostic (6.08e-2)" "unprognostic (1.35e-1)" "unprognostic (1.35e-3)" "unprognostic (1.18e-1)" "unprognostic (1.66e-1)" "unprognostic (2.72e-1)" "unprognostic (1.28e-1)" "unprognostic (1.42e-1)" "unprognostic (6.11e-2)" "unprognostic (1.45e-1)" "unprognostic (1.51e-1)" "unprognostic (3.80e-2)" "unprognostic (3.70e-2)" ARL5B ARL8 ENSG00000165997 "ADP ribosylation factor like GTPase 5B" Q96KC2 10 18659431-18681639 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 440.9;Endometrial luminal cells: 267.7;Epididymal basal cells: 304.9;monocytes: 260.2;Neutrophils: 389.5;Ocular epithelial cells: 375.4;Urothelial cells: 357.7" "Cell type enhanced" "Detected in all" "endothelial cell: 105.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027002 Approved NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 76: Non-specific - Metabolism" "Cluster 31: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 9 "HPA027002: " "unprognostic (5.19e-2)" "unprognostic (1.82e-1)" "unprognostic (7.07e-2)" "unprognostic (2.54e-1)" "unprognostic (2.82e-1)" "unprognostic (1.80e-1)" "unprognostic (9.82e-2)" "potential prognostic favorable (5.71e-4)" "unprognostic (3.67e-2)" "unprognostic (6.75e-3)" "potential prognostic favorable (8.96e-5)" "unprognostic (4.26e-3)" "unprognostic (7.01e-2)" "potential prognostic unfavorable (1.52e-4)" "unprognostic (2.04e-1)" "unprognostic (2.05e-2)" "unprognostic (5.76e-2)" "unprognostic (1.82e-1)" "unprognostic (8.52e-2)" "unprognostic (4.79e-1)" "unprognostic (1.66e-2)" "unprognostic (2.95e-2)" "unprognostic (3.37e-3)" "unprognostic (5.74e-2)" "unprognostic (6.95e-2)" "unprognostic (2.64e-2)" "unprognostic (4.55e-1)" "unprognostic (6.41e-2)" "unprognostic (1.64e-1)" "unprognostic (3.47e-3)" "unprognostic (2.21e-1)" ARL5C ARL12 ENSG00000141748 "ADP ribosylation factor like GTPase 5C" A6NH57 17 39156894-39167484 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 5 "lymphoid tissue: 3.2" "Group enriched" "Detected in some" 4 "Microglia: 17.0;pDCs: 22.2;Retinal bipolar cells: 44.6" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 19.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA069849 Uncertain NA NA "Cluster 80: Thymus - Adaptive immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "HPA069849: " ARL6 "BBS3, RP55" ENSG00000113966 "ADP ribosylation factor like GTPase 6" Q9H0F7 3 97764521-97801229 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Sensory transduction, Transport, Vision" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Intellectual disability, Obesity, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 35.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 134.6;Ependymal cells: 104.4;Respiratory ciliated cells: 136.1;Rod photoreceptor cells: 230.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 17.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019361 Approved Approved "Nucleoplasm,Microtubules,Primary cilium,Primary cilium tip,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 1: Neuronal - Visual perception" "Cluster 79: Photoreceptor cells - Phototransduction" 5 "Microtubules, Primary cilium" "Nucleoplasm, Primary cilium tip, Cytosol" "HPA019361: " "unprognostic (2.51e-1)" "unprognostic (8.75e-3)" "unprognostic (1.97e-2)" "unprognostic (2.82e-2)" "unprognostic (2.75e-1)" "unprognostic (7.61e-2)" "unprognostic (1.82e-1)" "unprognostic (1.36e-1)" "unprognostic (1.78e-1)" "unprognostic (1.20e-1)" "potential prognostic favorable (1.48e-7)" "unprognostic (3.69e-2)" "unprognostic (7.74e-3)" "unprognostic (9.35e-2)" "unprognostic (7.17e-2)" "unprognostic (1.28e-1)" "unprognostic (5.95e-2)" "unprognostic (2.61e-1)" "unprognostic (4.96e-2)" "unprognostic (2.46e-2)" "unprognostic (1.60e-1)" "unprognostic (2.72e-1)" "unprognostic (2.34e-1)" "unprognostic (1.82e-2)" "unprognostic (1.10e-1)" "unprognostic (1.76e-1)" "unprognostic (3.41e-2)" "unprognostic (1.73e-1)" "unprognostic (3.25e-2)" "unprognostic (5.04e-2)" ARL6IP1 "AIP1, ARL6IP, ARMER, KIAA0069, SPG61" ENSG00000170540 "ADP ribosylation factor like GTPase 6 interacting protein 1" Q15041 16 18791669-18801572 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enteric transient amplifying cells: 192.4;Epididymal basal cells: 354.3;Epididymal clear cells: 165.3;Epididymal efferent duct absorptive cells: 261.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Skeletal muscle - Endothelial cells, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" HPA045307 Uncertain Supported "Endoplasmic reticulum" NA Yes 39000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 14: Neurons - Synaptic function" "Cluster 54: Non-specific - Transcription" "Cluster 15: Non-specific - Protein processing" 97 "Endoplasmic reticulum" "HPA045307: " "unprognostic (2.48e-1)" "unprognostic (7.59e-2)" "unprognostic (6.06e-2)" "unprognostic (3.08e-1)" "unprognostic (7.95e-2)" "unprognostic (7.43e-2)" "unprognostic (4.75e-2)" "unprognostic (3.21e-1)" "unprognostic (1.61e-2)" "unprognostic (6.97e-3)" "potential prognostic favorable (2.93e-7)" "unprognostic (2.23e-1)" "unprognostic (3.64e-2)" "unprognostic (8.45e-2)" "unprognostic (3.15e-2)" "potential prognostic unfavorable (7.27e-4)" "unprognostic (2.06e-3)" "unprognostic (5.33e-2)" "unprognostic (3.34e-1)" "unprognostic (7.25e-2)" "unprognostic (2.93e-2)" "potential prognostic unfavorable (5.01e-4)" "unprognostic (9.54e-2)" "unprognostic (1.57e-1)" "unprognostic (5.26e-2)" "unprognostic (4.16e-2)" "unprognostic (3.13e-2)" "unprognostic (2.23e-1)" "unprognostic (2.56e-2)" "unprognostic (1.70e-2)" "unprognostic (2.56e-1)" ARL6IP4 "SFRS20, SR-25, SRp25, SRrp37" ENSG00000182196 "ADP ribosylation factor like GTPase 6 interacting protein 4" Q66PJ3 12 122980060-122982913 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 113.5;Enteric transient amplifying cells: 93.0;Enterocytes: 175.8;Epididymal efferent duct absorptive cells: 75.4;Epididymal principal cells: 72.2;Gastric chief cells: 76.4;Neuroendocrine cells: 75.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052098 Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 19: Astrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 15: Non-specific - Protein processing" 18 Nucleoplasm Mitochondria "HPA052098: " "unprognostic (4.38e-2)" "unprognostic (1.61e-2)" "unprognostic (3.48e-3)" "unprognostic (3.51e-1)" "unprognostic (4.74e-2)" "unprognostic (4.63e-1)" "unprognostic (1.51e-2)" "unprognostic (1.22e-3)" "unprognostic (3.67e-2)" "unprognostic (3.21e-3)" "potential prognostic favorable (8.26e-4)" "unprognostic (4.61e-2)" "unprognostic (9.93e-3)" "unprognostic (2.13e-3)" "potential prognostic unfavorable (8.19e-4)" "unprognostic (3.70e-1)" "unprognostic (2.07e-2)" "unprognostic (4.71e-2)" "unprognostic (8.87e-2)" "unprognostic (9.87e-2)" "unprognostic (1.13e-1)" "unprognostic (2.72e-2)" "unprognostic (1.91e-1)" "unprognostic (8.64e-2)" "unprognostic (3.26e-1)" "unprognostic (1.63e-2)" "unprognostic (1.52e-2)" "unprognostic (5.19e-2)" "unprognostic (1.73e-1)" "unprognostic (2.61e-1)" "unprognostic (4.68e-2)" ARL6IP5 "DERP11, GTRAP3-18, HSPC127, JWA, PRAF3, Yip6b" ENSG00000144746 "ADP ribosylation factor like GTPase 6 interacting protein 5" O75915 3 69084937-69106092 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Platelets: 1164.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Macrophages, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015540, CAB019321" Supported Approved "Endoplasmic reticulum" NA NA 780000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 108: Fibroblasts - ECM organization" 68 "Endoplasmic reticulum" "CAB019321: , HPA015540: " "unprognostic (3.97e-3)" "unprognostic (1.95e-2)" "unprognostic (2.53e-1)" "unprognostic (8.17e-2)" "unprognostic (4.54e-1)" "unprognostic (1.08e-1)" "unprognostic (2.21e-1)" "unprognostic (5.73e-3)" "unprognostic (2.31e-2)" "unprognostic (1.30e-2)" "unprognostic (1.07e-2)" "unprognostic (1.18e-2)" "potential prognostic favorable (4.25e-4)" "unprognostic (7.49e-2)" "unprognostic (8.36e-2)" "unprognostic (9.15e-2)" "unprognostic (5.49e-3)" "unprognostic (8.10e-2)" "unprognostic (1.46e-2)" "unprognostic (1.70e-2)" "unprognostic (1.88e-2)" "unprognostic (2.52e-2)" "unprognostic (1.57e-1)" "unprognostic (1.56e-1)" "unprognostic (6.16e-2)" "unprognostic (2.76e-1)" "unprognostic (2.20e-1)" "unprognostic (2.40e-1)" "unprognostic (8.41e-2)" "unprognostic (1.86e-1)" "unprognostic (1.45e-2)" ARL6IP6 MGC33864 ENSG00000177917 "ADP ribosylation factor like GTPase 6 interacting protein 6" Q8N6S5 2 152717647-152762396 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 53.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 220.3;Migrating cytotrophoblasts: 234.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 8 "basophil: 429.8;eosinophil: 302.0" "Lineage enriched" "Detected in all" 10 "granulocytes: 429.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014743 Approved Approved "Nuclear membrane,Cytosol" NA Yes "Cluster 41: Basophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 43 "Nuclear membrane" Cytosol "HPA014743: " "unprognostic (2.08e-1)" "unprognostic (2.17e-1)" "unprognostic (1.91e-1)" "unprognostic (1.06e-2)" "unprognostic (1.30e-2)" "unprognostic (8.15e-2)" "unprognostic (2.80e-1)" "unprognostic (1.15e-1)" "unprognostic (1.08e-1)" "unprognostic (5.07e-1)" "potential prognostic favorable (2.94e-4)" "unprognostic (1.01e-1)" "unprognostic (6.22e-3)" "unprognostic (1.28e-3)" "unprognostic (1.62e-3)" "unprognostic (2.80e-2)" "unprognostic (2.64e-2)" "unprognostic (3.80e-1)" "unprognostic (5.03e-2)" "unprognostic (1.45e-2)" "unprognostic (1.58e-1)" "unprognostic (1.48e-1)" "potential prognostic unfavorable (3.82e-4)" "unprognostic (2.31e-1)" "unprognostic (1.74e-3)" "unprognostic (2.09e-2)" "unprognostic (6.13e-2)" "unprognostic (1.23e-1)" "unprognostic (1.35e-1)" "unprognostic (4.62e-2)" "unprognostic (2.72e-1)" ARL8A "ARL10B, FLJ45195, Gie2" ENSG00000143862 "ADP ribosylation factor like GTPase 8A" Q96BM9 1 202133404-202144743 "Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 157.0" "Cell type enhanced" "Detected in many" "Neutrophils: 202.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038759, HPA040515, HPA045924" Approved NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 45: Non-specific - Nuclear processes" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 39 "HPA038759: , HPA040515: , HPA045924: " "unprognostic (1.92e-2)" "unprognostic (1.42e-1)" "unprognostic (2.04e-1)" "potential prognostic unfavorable (8.50e-5)" "unprognostic (7.10e-2)" "unprognostic (4.83e-3)" "unprognostic (7.99e-2)" "unprognostic (6.42e-2)" "unprognostic (2.27e-3)" "unprognostic (3.05e-1)" "potential prognostic favorable (1.86e-4)" "unprognostic (1.69e-2)" "unprognostic (5.09e-2)" "potential prognostic unfavorable (8.49e-4)" "unprognostic (9.14e-3)" "unprognostic (2.27e-1)" "unprognostic (7.10e-2)" "unprognostic (4.58e-2)" "unprognostic (9.41e-2)" "unprognostic (1.11e-1)" "unprognostic (1.37e-2)" "unprognostic (3.97e-2)" "unprognostic (1.27e-1)" "unprognostic (3.90e-1)" "unprognostic (9.74e-3)" "unprognostic (3.05e-1)" "unprognostic (1.25e-1)" "unprognostic (1.75e-2)" "unprognostic (5.15e-2)" "unprognostic (3.45e-3)" "unprognostic (1.39e-1)" ARL8B "ARL10C, FLJ10702, Gie1" ENSG00000134108 "ADP ribosylation factor like GTPase 8B" Q9NVJ2 3 5122249-5180911 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 607.1;monocytes: 502.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038759, HPA040515, HPA045924" Approved NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 66 "HPA038759: , HPA040515: , HPA045924: " "unprognostic (2.07e-2)" "unprognostic (1.21e-3)" "unprognostic (2.42e-1)" "unprognostic (2.29e-2)" "unprognostic (2.50e-1)" "unprognostic (9.48e-3)" "unprognostic (2.94e-1)" "potential prognostic unfavorable (1.57e-4)" "unprognostic (5.93e-2)" "unprognostic (3.20e-3)" "potential prognostic favorable (4.03e-6)" "unprognostic (3.63e-2)" "unprognostic (1.33e-2)" "validated prognostic unfavorable (9.53e-7)" "validated prognostic unfavorable (5.42e-4)" "unprognostic (3.23e-1)" "unprognostic (2.86e-1)" "unprognostic (1.59e-1)" "unprognostic (2.54e-1)" "unprognostic (4.56e-2)" "unprognostic (1.24e-2)" "unprognostic (1.75e-2)" "unprognostic (5.70e-2)" "unprognostic (9.69e-2)" "unprognostic (1.71e-1)" "unprognostic (2.53e-2)" "unprognostic (8.72e-2)" "unprognostic (5.36e-2)" "unprognostic (1.45e-1)" "unprognostic (2.49e-1)" "unprognostic (3.08e-1)" ARL9 ENSG00000196503 "ADP ribosylation factor like GTPase 9" Q6T311 4 56505209-56524959 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "choroid plexus: 11.0;testis: 8.3" "Cell type enhanced" "Detected in many" "Early spermatids: 113.2;Late primary spermatocytes: 97.7;Late spermatids: 442.5;Pituicytes/FSCs: 34.1;Retinal pigment epithelial cells: 59.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "thyroid cancer: 6.9" "Testis - Early spermatids, Testis - Late spermatids" "Region enhanced" "Detected in single" "cerebellum: 1.3" "Low region specificity" "Detected in all" "HPA058135, HPA072942" Enhanced Approved "Plasma membrane,Centriolar satellite,Cytosol" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" "Plasma membrane" "Centriolar satellite, Cytosol" "HPA058135: , HPA072942: " "unprognostic (3.70e-1)" "unprognostic (1.26e-1)" "unprognostic (2.06e-1)" "unprognostic (1.15e-1)" "unprognostic (1.36e-2)" "potential prognostic unfavorable (1.36e-5)" "unprognostic (1.34e-2)" "unprognostic (1.66e-2)" "potential prognostic unfavorable (4.59e-4)" "unprognostic (3.04e-2)" "unprognostic (1.81e-1)" "unprognostic (6.29e-2)" "unprognostic (6.76e-2)" "unprognostic (1.98e-2)" "unprognostic (8.18e-2)" "unprognostic (6.78e-2)" ARMC1 "Arcp, FLJ10511" ENSG00000104442 "Armadillo repeat containing 1" Q9NVT9 8 65602458-65634217 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 128.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026085 Approved Approved Mitochondria NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 62: Smooth muscle cells - Muscle contraction" 10 Mitochondria "HPA026085: " "unprognostic (8.30e-2)" "potential prognostic unfavorable (4.65e-4)" "unprognostic (1.48e-1)" "unprognostic (4.06e-2)" "unprognostic (1.97e-1)" "unprognostic (1.76e-1)" "unprognostic (1.95e-1)" "unprognostic (1.13e-2)" "unprognostic (2.69e-2)" "potential prognostic unfavorable (1.02e-6)" "potential prognostic favorable (7.02e-4)" "unprognostic (1.60e-1)" "unprognostic (5.72e-2)" "unprognostic (1.92e-3)" "unprognostic (1.01e-1)" "unprognostic (2.09e-2)" "unprognostic (6.06e-2)" "unprognostic (4.25e-2)" "unprognostic (4.39e-1)" "unprognostic (3.50e-1)" "unprognostic (3.83e-3)" "unprognostic (9.41e-3)" "unprognostic (1.39e-2)" "unprognostic (3.05e-1)" "unprognostic (3.15e-2)" "unprognostic (1.19e-1)" "unprognostic (5.87e-2)" "unprognostic (1.10e-1)" "unprognostic (2.64e-1)" "unprognostic (3.93e-2)" "unprognostic (1.22e-1)" ARMC10 "MGC3195, SVH" ENSG00000170632 "Armadillo repeat containing 10" Q8N2F6 7 103074881-103099759 "Predicted intracellular proteins, Predicted membrane proteins" "Growth regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 57.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011036, HPA011057" Enhanced Enhanced Mitochondria NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 27: Non-specific - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 98: Neurons - Neurotransmission & signaling" 1 Mitochondria "HPA011036: , HPA011057: " "unprognostic (8.68e-3)" "unprognostic (3.57e-1)" "unprognostic (7.72e-2)" "unprognostic (6.93e-2)" "unprognostic (2.56e-1)" "unprognostic (1.31e-2)" "unprognostic (2.09e-3)" "potential prognostic unfavorable (7.62e-4)" "unprognostic (1.04e-2)" "unprognostic (2.87e-1)" "potential prognostic favorable (4.45e-8)" "unprognostic (1.47e-1)" "unprognostic (6.10e-2)" "potential prognostic unfavorable (4.21e-5)" "unprognostic (4.40e-3)" "unprognostic (7.99e-2)" "unprognostic (1.63e-3)" "unprognostic (1.14e-1)" "unprognostic (1.67e-1)" "unprognostic (2.95e-1)" "unprognostic (1.77e-1)" "potential prognostic unfavorable (1.28e-4)" "unprognostic (1.44e-1)" "unprognostic (1.77e-1)" "unprognostic (5.16e-2)" "unprognostic (1.34e-1)" "unprognostic (1.89e-1)" "unprognostic (7.68e-2)" "unprognostic (4.25e-1)" "unprognostic (2.12e-1)" "unprognostic (1.90e-1)" ARMC12 "C6orf81, FLJ25390" ENSG00000157343 "Armadillo repeat containing 12" Q5T9G4 6 35737032-35749079 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 58.4" "Group enriched" "Detected in some" 4 "Early spermatids: 500.7;Late spermatids: 1622.6" "Cell type enhanced" "Detected in some" "astrocyte: 5.3;ependymal cell: 3.2" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 3.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA075457, HPA075777" Enhanced Supported Mitochondria NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 39: Astrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 3 Mitochondria "HPA075457: , HPA075777: " "unprognostic (3.84e-1)" "unprognostic (1.63e-1)" "unprognostic (2.07e-1)" ARMC2 "bA787I22.1, DKFZp434P0714" ENSG00000118690 "Armadillo repeat containing 2" Q8NEN0 6 108848416-108974476 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 31.2" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 640.4;Ependymal cells: 574.3;Fallopian tube ciliated cells: 256.8;Late spermatids: 223.0;Respiratory ciliated cells: 515.2" "Cell type enhanced" "Detected in all" "ependymal cell: 600.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025809, HPA053696" Enhanced Uncertain Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 34: Ciliated cells - Cilia assembly & function" Nucleoplasm "HPA025809: , HPA053696: " "unprognostic (1.45e-2)" "unprognostic (1.07e-3)" "unprognostic (1.44e-1)" "unprognostic (5.65e-3)" "unprognostic (2.17e-1)" "unprognostic (1.04e-1)" "unprognostic (1.18e-1)" "unprognostic (3.90e-2)" "unprognostic (2.11e-1)" "unprognostic (1.01e-3)" "unprognostic (6.29e-2)" "unprognostic (2.06e-1)" "unprognostic (1.18e-1)" "potential prognostic unfavorable (9.10e-6)" "unprognostic (1.09e-1)" "unprognostic (2.53e-3)" "unprognostic (8.13e-3)" "unprognostic (3.34e-1)" "unprognostic (8.46e-2)" "unprognostic (1.09e-1)" "unprognostic (1.80e-1)" "unprognostic (3.21e-3)" "unprognostic (2.87e-3)" "unprognostic (4.06e-2)" "unprognostic (2.62e-2)" "potential prognostic favorable (1.56e-6)" "unprognostic (6.95e-2)" "unprognostic (2.31e-1)" "unprognostic (7.14e-2)" "potential prognostic unfavorable (2.81e-4)" "unprognostic (9.87e-3)" ARMC3 "CT81, FLJ32827" ENSG00000165309 "Armadillo repeat containing 3" Q5W041 10 22928024-23038523 "Predicted intracellular proteins" "Autophagy, Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "choroid plexus: 48.7;fallopian tube: 41.9;testis: 31.4" "Group enriched" "Detected in many" 5 "Choroid plexus epithelial cells: 996.3;Early spermatids: 499.9;Endometrial ciliated cells: 641.1;Ependymal cells: 1543.9;Epididymal efferent duct ciliated cells: 605.6;Fallopian tube ciliated cells: 732.1;Late primary spermatocytes: 396.8;Respiratory ciliated cells: 862.0" "Group enriched" "Detected in many" 21 "choroid plexus epithelial cell: 742.3;ependymal cell: 1693.2" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 11.7" "Region enhanced" "Detected in all" "choroid plexus: 70.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 2.7" "Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA037823, HPA037824" Enhanced NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" "HPA037823: , HPA037824: " "unprognostic (1.73e-2)" "unprognostic (7.17e-2)" "unprognostic (1.58e-1)" "unprognostic (1.11e-1)" "unprognostic (3.82e-2)" "unprognostic (1.58e-2)" "unprognostic (2.15e-1)" "unprognostic (1.50e-2)" "unprognostic (8.15e-2)" "unprognostic (6.89e-3)" "unprognostic (1.27e-2)" "unprognostic (6.35e-2)" ARMC5 FLJ13063 ENSG00000140691 "Armadillo repeat containing 5" Q96C12 16 31458080-31467166 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Cushing syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 45.6;Hepatocytes: 34.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041524, HPA063706" Approved Approved "Nucleoplasm,Focal adhesion sites,Cytosol" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 24: Non-specific - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 13 "Nucleoplasm, Cytosol" "Focal adhesion sites" "HPA041524: , HPA063706: " "unprognostic (1.03e-1)" "unprognostic (2.21e-1)" "unprognostic (3.91e-1)" "unprognostic (7.17e-2)" "unprognostic (5.09e-2)" "unprognostic (1.58e-1)" "unprognostic (1.46e-2)" "unprognostic (7.17e-3)" "unprognostic (5.11e-2)" "unprognostic (3.78e-2)" "unprognostic (2.41e-1)" "unprognostic (2.65e-1)" "unprognostic (1.73e-1)" "unprognostic (8.43e-2)" "unprognostic (1.12e-2)" "unprognostic (3.19e-2)" "unprognostic (5.60e-2)" "unprognostic (1.13e-1)" "unprognostic (1.04e-2)" "unprognostic (2.80e-2)" "unprognostic (2.13e-2)" "potential prognostic favorable (5.63e-5)" "unprognostic (2.35e-1)" "unprognostic (7.57e-2)" "unprognostic (7.82e-2)" "unprognostic (1.25e-2)" "unprognostic (1.34e-1)" "unprognostic (8.46e-2)" "unprognostic (2.37e-1)" "unprognostic (1.20e-1)" "unprognostic (1.55e-1)" ARMC6 MGC19595 ENSG00000105676 "Armadillo repeat containing 6" Q6NXE6 19 19033575-19060311 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 111.9" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 55.7;Hepatocytes: 66.5;Late spermatids: 88.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041420, HPA041681" Supported Enhanced Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 1: Neurons - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 93: Hepatocytes - Bile production & excretion" 6 Cytosol "HPA041420: , HPA041681: " "unprognostic (5.63e-2)" "unprognostic (3.45e-2)" "unprognostic (3.73e-1)" "unprognostic (3.98e-1)" "unprognostic (2.97e-1)" "unprognostic (1.01e-1)" "unprognostic (3.04e-2)" "unprognostic (1.27e-1)" "unprognostic (1.97e-2)" "unprognostic (5.19e-2)" "unprognostic (2.69e-1)" "unprognostic (1.29e-1)" "unprognostic (1.76e-1)" "unprognostic (1.95e-2)" "unprognostic (2.38e-2)" "unprognostic (2.41e-1)" "unprognostic (1.18e-1)" "unprognostic (1.33e-1)" "unprognostic (9.40e-3)" "unprognostic (3.49e-1)" "unprognostic (2.94e-1)" "unprognostic (1.29e-2)" "unprognostic (3.62e-1)" "unprognostic (3.61e-1)" "unprognostic (5.64e-2)" "potential prognostic favorable (3.32e-4)" "unprognostic (6.71e-2)" "unprognostic (1.83e-1)" "unprognostic (8.87e-2)" "unprognostic (1.07e-1)" "unprognostic (6.60e-2)" ARMC7 FLJ22160 ENSG00000125449 "Armadillo repeat containing 7" Q9H6L4 17 75109952-75130272 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 50.7;Paneth cells: 65.7;Renal collecting duct intercalated cells: 60.5;Renal collecting duct principal cells: 56.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "HPA024229, HPA053076" Uncertain Supported Cytosol NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 72: Kidney - Transmembrane transport" "Cluster 35: Non-specific - DNA binding" "Cluster 27: Breast cancer - Unknown function" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 63 Cytosol "HPA024229: , HPA053076: " "unprognostic (1.70e-1)" "unprognostic (2.26e-1)" "unprognostic (3.46e-1)" "unprognostic (4.36e-3)" "unprognostic (4.04e-1)" "unprognostic (5.06e-2)" "unprognostic (5.99e-2)" "unprognostic (4.17e-2)" "unprognostic (3.95e-1)" "unprognostic (3.26e-2)" "unprognostic (1.57e-3)" "unprognostic (6.68e-2)" "potential prognostic favorable (2.27e-4)" "potential prognostic unfavorable (5.40e-6)" "unprognostic (7.42e-3)" "unprognostic (1.05e-1)" "unprognostic (2.05e-1)" "unprognostic (2.34e-1)" "potential prognostic favorable (1.09e-4)" "unprognostic (2.14e-2)" "unprognostic (7.20e-3)" "unprognostic (2.53e-2)" "unprognostic (2.80e-1)" "unprognostic (7.58e-2)" "unprognostic (2.45e-1)" "unprognostic (3.11e-1)" "unprognostic (2.19e-1)" "unprognostic (1.36e-2)" "unprognostic (7.79e-2)" "unprognostic (9.92e-3)" "unprognostic (2.27e-1)" ARMC8 "DKFZP434A043, GID5, HSPC056, VID28" ENSG00000114098 "Armadillo repeat containing 8" Q8IUR7 3 138187248-138298384 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 322.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036996, HPA044869" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - DNA binding" "Cluster 63: Non-specific - Protein processing" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 65 Nucleoplasm "Vesicles, Cytosol" "HPA036996: , HPA044869: " "unprognostic (1.38e-1)" "unprognostic (1.18e-2)" "unprognostic (2.83e-1)" "unprognostic (4.45e-2)" "unprognostic (3.95e-1)" "unprognostic (2.03e-2)" "unprognostic (1.35e-1)" "unprognostic (4.25e-3)" "unprognostic (3.21e-1)" "unprognostic (2.88e-3)" "potential prognostic favorable (1.60e-5)" "unprognostic (8.05e-2)" "unprognostic (9.35e-2)" "unprognostic (1.92e-2)" "unprognostic (1.23e-1)" "unprognostic (1.24e-1)" "unprognostic (2.70e-2)" "unprognostic (1.19e-1)" "unprognostic (3.40e-1)" "unprognostic (9.39e-2)" "unprognostic (1.80e-2)" "unprognostic (5.91e-2)" "unprognostic (1.15e-3)" "unprognostic (6.68e-2)" "unprognostic (3.99e-2)" "unprognostic (5.49e-2)" "unprognostic (1.13e-2)" "unprognostic (2.89e-1)" "unprognostic (1.66e-1)" "unprognostic (7.59e-2)" "unprognostic (3.09e-2)" ARMC9 "ARM, FLJ12584, KIAA1868, KU-MEL-1" ENSG00000135931 "Armadillo repeat containing 9" Q7Z3E5 2 231198546-231376848 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Joubert syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 40.6" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 376.4;Cone photoreceptor cells: 1453.2;Retinal pigment epithelial cells: 481.7;Rod photoreceptor cells: 1251.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 1.4" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in all" "Rhabdoid: 67.8" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Liver - Vascular endothelial cells, Lung - Alveolar cells type 2, Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019041, HPA026671" Approved Approved "Flagellar centriole,Mid piece,Annulus" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 5: Rhabdoid - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" 1 "Flagellar centriole" "Mid piece, Annulus" "HPA019041: , HPA026671: " "unprognostic (2.85e-2)" "unprognostic (5.58e-2)" "unprognostic (1.03e-1)" "unprognostic (3.20e-1)" "unprognostic (2.55e-2)" "unprognostic (3.04e-2)" "unprognostic (1.17e-1)" "unprognostic (1.24e-2)" "unprognostic (2.11e-2)" "unprognostic (8.28e-3)" "unprognostic (1.86e-1)" "unprognostic (1.65e-1)" "unprognostic (1.55e-1)" "unprognostic (3.83e-3)" "unprognostic (4.78e-3)" "unprognostic (7.09e-2)" "unprognostic (1.38e-3)" "potential prognostic unfavorable (2.06e-4)" "unprognostic (1.40e-1)" "unprognostic (3.88e-2)" "unprognostic (2.18e-2)" "unprognostic (1.76e-1)" "unprognostic (8.91e-3)" "unprognostic (1.75e-2)" "unprognostic (2.40e-1)" "unprognostic (5.88e-3)" "unprognostic (5.17e-1)" "unprognostic (7.85e-2)" "unprognostic (2.06e-1)" "unprognostic (1.52e-1)" "unprognostic (1.15e-1)" ARMCX1 "ALEX1, GASP7" ENSG00000126947 "Armadillo repeat containing X-linked 1" Q9P291 X 101550547-101554700 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 69.4;Melanocytes: 59.8;Ovarian stromal cells: 68.3;Schwann cells: 53.4;Smooth muscle cells: 78.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 7.7" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Sarcoma: 28.9" "Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000268, HPA005685, CAB020695" Supported Supported Nucleoplasm,Mitochondria,Cytosol No No "Cluster 2: Dendritic cells - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 14: Neurons - Synaptic function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 94: Gonadal somatic cells - Mixed function" 6 Mitochondria "Nucleoplasm, Cytosol" "CAB020695: , HPA000268: , HPA005685: " "unprognostic (2.20e-1)" "unprognostic (2.15e-1)" "unprognostic (1.21e-1)" "unprognostic (4.73e-3)" "unprognostic (9.96e-3)" "unprognostic (2.33e-2)" "unprognostic (1.92e-1)" "unprognostic (6.63e-3)" "unprognostic (1.59e-1)" "unprognostic (6.38e-2)" "potential prognostic favorable (2.43e-5)" "unprognostic (8.89e-2)" "unprognostic (1.39e-1)" "potential prognostic unfavorable (2.89e-4)" "unprognostic (4.59e-2)" "unprognostic (6.14e-2)" "unprognostic (4.19e-2)" "unprognostic (2.55e-1)" "unprognostic (7.34e-2)" "unprognostic (7.94e-2)" "unprognostic (2.06e-1)" "potential prognostic favorable (9.62e-4)" "unprognostic (1.19e-1)" "unprognostic (2.83e-1)" "unprognostic (9.39e-2)" "unprognostic (2.00e-3)" "unprognostic (2.37e-2)" "unprognostic (3.39e-3)" "unprognostic (1.39e-1)" "unprognostic (1.23e-1)" "unprognostic (2.26e-2)" ARMCX2 "ALEX2, GASP9, KIAA0512" ENSG00000184867 "Armadillo repeat containing X-linked 2" Q7L311 X 101655281-101659850 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 146.2" "Cell type enhanced" "Detected in many" "Epididymal basal cells: 65.1;Epididymal clear cells: 73.5;Epididymal efferent duct absorptive cells: 54.9;Epididymal principal cells: 144.6;Somatotrophs: 57.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Thyroid Carcinoma (TCGA): 93.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "testis cancer: 83.2" "Adrenal gland - Adrenal cortex cells, Liver - Vascular endothelial cells, Pituitary gland - Somatotropes, Skeletal muscle - Fibroblasts, Spleen - Endothelial cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005761 Enhanced Approved Nucleoplasm,Mitochondria Yes No "Cluster 34: B-cells - Unknown function" "Cluster 22: Epididymis - Mixed function" "Cluster 14: Neurons - Synaptic function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" Mitochondria Nucleoplasm "HPA005761: " "unprognostic (6.94e-3)" "unprognostic (9.30e-2)" "unprognostic (2.49e-1)" "unprognostic (3.47e-2)" "unprognostic (2.23e-2)" "unprognostic (2.81e-1)" "unprognostic (1.21e-1)" "unprognostic (1.20e-1)" "unprognostic (1.93e-1)" "unprognostic (1.10e-2)" "potential prognostic favorable (9.43e-4)" "unprognostic (4.09e-1)" "unprognostic (3.87e-3)" "unprognostic (2.38e-2)" "unprognostic (1.31e-2)" "unprognostic (1.24e-1)" "unprognostic (8.23e-3)" "unprognostic (4.68e-2)" "unprognostic (2.78e-1)" "unprognostic (3.49e-1)" "unprognostic (3.49e-1)" "potential prognostic favorable (5.97e-5)" "unprognostic (1.15e-1)" "unprognostic (3.74e-2)" "unprognostic (8.26e-2)" "unprognostic (2.24e-1)" "unprognostic (2.36e-2)" "potential prognostic unfavorable (2.67e-4)" "unprognostic (1.58e-2)" "unprognostic (1.22e-1)" "unprognostic (1.30e-1)" ARMCX3 "ALEX3, GASP6" ENSG00000102401 "Armadillo repeat containing X-linked 3" Q9UH62 X 101622797-101627843 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 328.3;Platelets: 283.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Thyroid Carcinoma (TCGA): 168.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skin - Endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000325, HPA000967, HPA001530" Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 58: Mast cells - Allergic inflammatory responses" 17 Nucleoplasm "Golgi apparatus, Cytosol" "HPA000325: , HPA000967: , HPA001530: " "potential prognostic favorable (2.03e-4)" "unprognostic (8.24e-2)" "unprognostic (1.35e-1)" "unprognostic (1.88e-1)" "unprognostic (2.44e-1)" "unprognostic (7.12e-3)" "unprognostic (5.27e-2)" "unprognostic (1.10e-1)" "unprognostic (5.63e-2)" "unprognostic (9.34e-2)" "potential prognostic favorable (1.82e-7)" "unprognostic (4.37e-3)" "unprognostic (2.31e-2)" "unprognostic (1.83e-2)" "unprognostic (1.68e-2)" "unprognostic (9.10e-3)" "unprognostic (6.62e-2)" "unprognostic (1.49e-1)" "unprognostic (4.99e-1)" "unprognostic (8.52e-2)" "unprognostic (9.05e-3)" "unprognostic (3.62e-2)" "unprognostic (1.65e-1)" "unprognostic (2.92e-2)" "unprognostic (2.49e-2)" "unprognostic (2.29e-1)" "unprognostic (2.24e-2)" "unprognostic (1.33e-2)" "unprognostic (2.37e-1)" "unprognostic (7.10e-3)" "unprognostic (1.28e-1)" ARMCX4 "CXorf35, GASP4, MGC40053" ENSG00000196440 "Armadillo repeat containing X-linked 4" Q5H9R4 X 101418287-101533459 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Sertoli cells: 237.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skeletal muscle - Fibroblasts, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000429, HPA051930" Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 75: Ovary - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 7: Non-specific - Transcription" Nucleoplasm Vesicles "HPA000429: , HPA051930: " "unprognostic (1.62e-3)" "unprognostic (2.90e-1)" "unprognostic (3.89e-2)" "unprognostic (2.32e-1)" "unprognostic (2.51e-2)" "potential prognostic favorable (1.65e-4)" "unprognostic (3.18e-2)" "validated prognostic favorable (6.36e-4)" "validated prognostic favorable (7.99e-4)" "unprognostic (5.02e-2)" "unprognostic (2.95e-3)" "unprognostic (4.79e-2)" "unprognostic (1.35e-1)" "unprognostic (3.04e-1)" "unprognostic (2.03e-2)" "potential prognostic favorable (7.89e-4)" "unprognostic (1.62e-2)" "unprognostic (1.09e-1)" "potential prognostic favorable (2.80e-4)" "unprognostic (8.29e-2)" "unprognostic (2.63e-1)" "unprognostic (4.99e-2)" ARMCX5 "FLJ12969, GASP5" ENSG00000125962 "Armadillo repeat containing X-linked 5" Q6P1M9 X 102599168-102604159 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Distal convoluted tubule cells: 6.5;Epicardial cells: 4.5;Loop of henle epithelial cells: 5.3;Papillary tip epithelial cells: 5.5;Podocytes: 3.6;Proximal tubule cells: 4.7;Renal collecting duct intercalated cells: 5.4;Renal collecting duct principal cells: 5.4;Renal connecting tubule cells: 4.7" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000996 Approved Approved "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 53: Neurons - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 105: Non-specific - Mixed function" 16 "Nuclear speckles, Cytosol" "Plasma membrane" "HPA000996: " "unprognostic (2.64e-3)" "unprognostic (9.06e-2)" "unprognostic (1.56e-1)" "unprognostic (1.97e-1)" "unprognostic (3.92e-1)" "unprognostic (1.63e-1)" "unprognostic (1.69e-1)" "unprognostic (3.22e-2)" "unprognostic (2.02e-2)" "unprognostic (5.48e-2)" "potential prognostic favorable (4.90e-6)" "unprognostic (7.31e-3)" "unprognostic (1.33e-1)" "unprognostic (4.05e-2)" "unprognostic (1.16e-1)" "unprognostic (1.42e-1)" "unprognostic (2.26e-3)" "unprognostic (6.41e-2)" "unprognostic (2.30e-1)" "unprognostic (1.77e-1)" "unprognostic (1.20e-1)" "unprognostic (1.33e-1)" "unprognostic (2.77e-1)" "unprognostic (2.48e-2)" "unprognostic (1.77e-2)" "unprognostic (5.12e-1)" "unprognostic (2.71e-1)" "unprognostic (1.07e-1)" "unprognostic (5.96e-2)" "unprognostic (1.39e-1)" "unprognostic (4.57e-1)" ARMCX5-GPRASP2 ENSG00000286237 "ARMCX5-GPRASP2 readthrough" X 102712495-102753530 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 9.2;Gonadotrophs: 3.1;Granulosa cells: 4.9;Lactotrophs: 4.3;Thyrotrophs: 4.2" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA000887 Uncertain Nucleoplasm,Cytosol NA NA "Cluster 65: Brain - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 4 Cytosol Nucleoplasm "HPA000887: " "unprognostic (2.80e-1)" ARMCX6 "FLJ20811, GASP10" ENSG00000198960 "Armadillo repeat containing X-linked 6" Q7L4S7 X 101615118-101618001 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Megakaryocytes: 18.5;Platelets: 12.6;Podocytes: 9.8;Renal collecting duct principal cells: 9.8" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 3.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043030, HPA048125" Approved Supported "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 36: Non-specific - mRNA processing" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 2 Cytosol "Nucleoplasm, Nuclear membrane" "HPA043030: , HPA048125: " "unprognostic (6.54e-2)" "unprognostic (2.68e-2)" "unprognostic (2.61e-2)" "unprognostic (2.56e-2)" "unprognostic (5.25e-2)" "unprognostic (9.58e-2)" "potential prognostic favorable (9.41e-4)" "unprognostic (3.57e-2)" "unprognostic (2.45e-2)" "unprognostic (2.10e-1)" "potential prognostic favorable (2.85e-5)" "unprognostic (2.91e-3)" "unprognostic (1.83e-1)" "unprognostic (3.01e-3)" "unprognostic (2.41e-2)" "unprognostic (1.90e-3)" "unprognostic (7.88e-2)" "unprognostic (2.19e-1)" "unprognostic (1.30e-1)" "unprognostic (1.89e-1)" "unprognostic (1.20e-1)" "unprognostic (3.21e-1)" "unprognostic (4.84e-1)" "unprognostic (1.41e-1)" "unprognostic (3.63e-3)" "unprognostic (4.99e-3)" "unprognostic (9.04e-2)" "unprognostic (1.70e-1)" "unprognostic (1.76e-1)" "unprognostic (1.76e-2)" "unprognostic (7.75e-2)" ARMH1 "C1orf228, MGC33556, NCRNA00082, p40" ENSG00000198520 "Armadillo like helical domain containing 1" Q6PIY5 1 44674692-44725591 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 7.7;testis: 10.9" "Cell type enhanced" "Detected in many" "Astrocytes: 121.3;Choroid plexus epithelial cells: 126.7;Ependymal cells: 225.8;Late spermatids: 90.6;Respiratory ciliated cells: 239.3;Thymocytes: 87.2" "Cell type enhanced" "Detected in all" "ependymal cell: 224.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 8.8" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Leukemia: 3.8" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA034769, HPA034770" Uncertain Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 34: Ciliated cells - Cilia assembly & function" "Plasma membrane, Cytosol" "HPA034769: , HPA034770: " "unprognostic (7.21e-2)" "unprognostic (1.76e-1)" "unprognostic (1.00e-1)" "unprognostic (1.73e-1)" "unprognostic (2.05e-2)" "unprognostic (1.15e-1)" "unprognostic (8.00e-3)" "unprognostic (1.70e-3)" "unprognostic (1.10e-1)" "unprognostic (2.86e-1)" "unprognostic (2.36e-2)" "unprognostic (2.62e-2)" ARMH2 C6orf229 ENSG00000260286 "Armadillo like helical domain containing 2" H3BNL8 6 24797335-24798917 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "testis: 12.5" "Group enriched" "Detected in some" 5 "Early spermatids: 19.6;Late primary spermatocytes: 49.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "neutrophil: 2.5" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Spleen - Neutrophils_2, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 47: Testis - Mixed function" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" ARMH3 "C10orf76, FLJ13114" ENSG00000120029 "Armadillo like helical domain containing 3" Q5T2E6 10 101845599-102056193 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Myonuclei: 356.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050913, HPA053580" Approved Approved Vesicles NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 7: Non-specific - Transcription" Vesicles "HPA050913: , HPA053580: " "unprognostic (5.50e-2)" "unprognostic (2.28e-2)" "unprognostic (1.41e-1)" "unprognostic (9.30e-2)" "unprognostic (1.67e-2)" "unprognostic (2.60e-1)" "unprognostic (3.32e-3)" "unprognostic (3.28e-2)" "unprognostic (1.57e-1)" "potential prognostic favorable (1.15e-5)" "unprognostic (1.67e-2)" "unprognostic (1.50e-1)" "unprognostic (1.07e-1)" "unprognostic (3.44e-2)" "unprognostic (1.50e-1)" "unprognostic (6.36e-2)" "unprognostic (2.66e-1)" "unprognostic (7.83e-3)" "unprognostic (7.18e-3)" "unprognostic (3.09e-3)" "unprognostic (1.72e-2)" "unprognostic (1.65e-1)" "unprognostic (8.77e-3)" "unprognostic (6.97e-2)" "unprognostic (2.10e-1)" "unprognostic (1.20e-1)" "unprognostic (1.40e-1)" "unprognostic (4.21e-2)" "unprognostic (2.00e-2)" ARMH4 "C14orf37, UT2" ENSG00000139971 "Armadillo like helical domain containing 4" Q86TY3 14 57999735-58298139 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 7.8" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 485.0;Epicardial cells: 277.4;Podocytes: 1276.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Kidney - Podocytes, Lung - Fibroblasts_2, Prostate - Fibroblasts, Spleen - Fibroblasts_1, Spleen - Fibroblasts_2, Testis - Sertoli cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001580, HPA001789" Enhanced Approved "Plasma membrane" NA NA 1300000 "Cluster 72: Kidney - Transmembrane transport" "Cluster 24: Neurons - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 57: Podocytes - Glomerular filtration" 1 "Plasma membrane" "HPA001580: , HPA001789: " "unprognostic (1.77e-1)" "unprognostic (1.21e-1)" "unprognostic (2.98e-2)" "unprognostic (3.02e-1)" "unprognostic (1.11e-3)" "unprognostic (1.45e-1)" "unprognostic (8.98e-2)" "unprognostic (9.05e-3)" "unprognostic (1.16e-1)" "unprognostic (5.21e-3)" "unprognostic (8.58e-2)" "unprognostic (1.88e-1)" "unprognostic (1.26e-2)" "unprognostic (4.00e-2)" "unprognostic (2.29e-1)" "unprognostic (8.28e-2)" "unprognostic (2.16e-1)" "unprognostic (2.77e-1)" "unprognostic (1.03e-1)" ARMS2 "ARMD8, LOC387715" ENSG00000254636 "Age-related maculopathy susceptibility 2" P0C7Q2 10 122454653-122457352 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Age-related macular degeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 1.3;testis: 2.7" "Cell type enriched" "Detected in some" 4 "Late spermatids: 103.3" "Cell type enhanced" "Detected in some" "LAMP5-LHX6 and Chandelier: 2.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells, Testis - Early spermatids, Testis - Late spermatids" HPA067225 Enhanced Approved "Principal piece,End piece" NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 1: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 2 "End piece" "Principal piece" "HPA067225: " ARMT1 "C6orf211, FLJ12910" ENSG00000146476 "Acidic residue methyltransferase 1" Q9H993 6 151452258-151470101 "Predicted intracellular proteins" "DNA damage" "Hydrolase, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 74.9" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Breast Invasive Carcinoma (TCGA): 87.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003004, HPA005819" Uncertain Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 310000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 76: Non-specific - Metabolism" "Cluster 1: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 9 "Nuclear bodies" "Nucleoplasm, Cytosol" "HPA003004: , HPA005819: " "unprognostic (3.33e-1)" "unprognostic (1.04e-3)" "unprognostic (6.12e-3)" "validated prognostic favorable (9.87e-4)" "validated prognostic favorable (8.84e-5)" "unprognostic (1.90e-1)" "unprognostic (2.33e-1)" "unprognostic (9.06e-2)" "unprognostic (3.69e-2)" "potential prognostic favorable (2.63e-7)" "unprognostic (9.09e-2)" "unprognostic (1.55e-1)" "unprognostic (6.01e-3)" "unprognostic (1.52e-3)" "unprognostic (3.01e-1)" "unprognostic (2.76e-1)" "unprognostic (9.26e-2)" "unprognostic (1.70e-1)" "unprognostic (3.59e-2)" "unprognostic (1.15e-1)" "unprognostic (4.42e-2)" "unprognostic (1.28e-1)" "unprognostic (1.11e-1)" "unprognostic (1.43e-1)" "unprognostic (2.64e-2)" "unprognostic (1.82e-1)" "unprognostic (1.07e-1)" "unprognostic (1.73e-1)" "unprognostic (2.68e-1)" ARNT "bHLHe2, HIF-1beta" ENSG00000143437 "Aryl hydrocarbon receptor nuclear translocator" P27540 1 150809713-150876708 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Lung - Fibroblasts_1, Prostate - Fibroblasts, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001759, CAB004318" Supported Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 75: Ovary - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 45: Non-specific - Nuclear processes" "Cluster 108: Fibroblasts - ECM organization" 44 "Nucleoplasm, Nuclear bodies" "CAB004318: , HPA001759: " "unprognostic (1.75e-2)" "unprognostic (1.02e-1)" "unprognostic (1.54e-1)" "unprognostic (2.66e-2)" "unprognostic (3.41e-1)" "unprognostic (7.97e-2)" "unprognostic (3.17e-1)" "unprognostic (2.22e-1)" "unprognostic (1.26e-1)" "unprognostic (8.62e-3)" "validated prognostic favorable (9.25e-5)" "validated prognostic favorable (3.47e-4)" "unprognostic (1.74e-1)" "unprognostic (3.02e-2)" "unprognostic (3.25e-2)" "unprognostic (1.12e-1)" "unprognostic (1.13e-1)" "unprognostic (3.21e-1)" "unprognostic (8.32e-2)" "unprognostic (6.49e-3)" "unprognostic (8.12e-3)" "unprognostic (2.27e-1)" "unprognostic (2.76e-1)" "unprognostic (1.63e-1)" "unprognostic (1.43e-2)" "unprognostic (2.17e-1)" "unprognostic (3.55e-1)" "unprognostic (1.79e-1)" "unprognostic (2.25e-1)" "unprognostic (2.15e-2)" "unprognostic (2.12e-1)" ARNT2 "bHLHe1, KIAA0307" ENSG00000172379 "Aryl hydrocarbon receptor nuclear translocator 2" Q9HBZ2 15 80404350-80597933 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 97.5" "Cell type enhanced" "Detected in many" "Astrocytes: 368.8;Bergmann glia: 254.0;Brain excitatory neurons: 186.8;Brain inhibitory neurons: 270.0;Choroid plexus epithelial cells: 221.7;Distal convoluted tubule cells: 271.9;Ependymal cells: 484.3;Oligodendrocyte progenitor cells: 377.8;Pituicytes/FSCs: 200.2;Renal collecting duct intercalated cells: 202.7;Sertoli cells: 188.5" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 52.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 26.1" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001056, CAB005081" Enhanced Supported Nucleoplasm NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 104: Brain endothelial cells - Blood brain barrier" 26 Nucleoplasm "CAB005081: , HPA001056: " "unprognostic (7.47e-3)" "unprognostic (7.19e-2)" "unprognostic (7.22e-2)" "unprognostic (3.20e-1)" "unprognostic (2.51e-2)" "unprognostic (1.01e-1)" "unprognostic (1.30e-1)" "unprognostic (3.17e-1)" "unprognostic (5.46e-2)" "unprognostic (5.80e-2)" "potential prognostic favorable (4.77e-4)" "unprognostic (3.61e-3)" "unprognostic (1.64e-1)" "unprognostic (4.84e-2)" "unprognostic (1.65e-1)" "unprognostic (1.94e-1)" "unprognostic (1.58e-1)" "unprognostic (1.45e-1)" "unprognostic (2.35e-1)" "unprognostic (2.90e-1)" "unprognostic (2.05e-1)" "potential prognostic favorable (2.75e-6)" "unprognostic (9.93e-2)" "unprognostic (6.67e-2)" "unprognostic (1.67e-2)" "unprognostic (9.88e-2)" "unprognostic (1.07e-1)" "unprognostic (2.74e-1)" "unprognostic (2.54e-1)" "unprognostic (1.49e-1)" "unprognostic (1.05e-1)" ARPC1A "Arc40, SOP2Hs, SOP2L" ENSG00000241685 "Actin related protein 2/3 complex subunit 1A" Q92747 7 99325898-99366262 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 65.9;Gastric chief cells: 86.3;Parietal cells: 99.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004334 Approved Approved "Cell Junctions,Cytosol" NA NA 200000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 74: Non-specific - Signal transduction" "Cluster 14: Neurons - Synaptic function" "Cluster 39: Non-specific - Transcription" "Cluster 98: Neurons - Neurotransmission & signaling" 67 "Cell Junctions" Cytosol "HPA004334: " "unprognostic (6.79e-2)" "unprognostic (6.84e-3)" "unprognostic (3.02e-2)" "unprognostic (3.31e-1)" "unprognostic (6.78e-2)" "unprognostic (1.78e-1)" "unprognostic (2.19e-3)" "potential prognostic unfavorable (6.99e-4)" "unprognostic (1.36e-2)" "potential prognostic unfavorable (5.99e-4)" "potential prognostic favorable (1.25e-4)" "unprognostic (9.24e-2)" "unprognostic (3.31e-2)" "unprognostic (1.19e-3)" "potential prognostic unfavorable (2.24e-6)" "potential prognostic unfavorable (6.03e-4)" "unprognostic (1.09e-3)" "unprognostic (3.90e-2)" "unprognostic (2.17e-1)" "unprognostic (1.44e-1)" "unprognostic (3.15e-1)" "unprognostic (8.99e-3)" "unprognostic (2.16e-2)" "unprognostic (5.92e-2)" "unprognostic (1.03e-1)" "unprognostic (1.11e-1)" "unprognostic (1.22e-1)" "unprognostic (1.45e-1)" "unprognostic (1.76e-1)" "unprognostic (6.15e-2)" "unprognostic (1.48e-1)" ARPC1B "ARC41, p40-ARC, p41-ARC" ENSG00000130429 "Actin related protein 2/3 complex subunit 1B" O15143 7 99374249-99394816 "Disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 288.1" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 824.2;Hofbauer cells: 687.0;Kupffer cells: 894.7;Megakaryocytes: 1755.6;monocytes: 470.4;Neutrophils: 501.0;Platelets: 2879.8" "Group enriched" "Detected in all" 5 "central nervous system macrophage: 164.0;endothelial cell: 88.0;leukocyte: 185.5;pericyte: 63.7;vascular associated smooth muscle cell: 98.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Macrophages, Breast - Macrophages, Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004832 Enhanced Supported Vesicles,Cytosol NA NA 11000000 "Cluster 29: Non-specific - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 39: Non-specific - Transcription" "Cluster 47: Platelets - Hemostasis" 60 "Vesicles, Cytosol" "HPA004832: " "unprognostic (5.10e-2)" "unprognostic (2.79e-1)" "unprognostic (2.88e-2)" "unprognostic (1.86e-2)" "unprognostic (2.34e-1)" "unprognostic (7.49e-3)" "unprognostic (1.71e-2)" "unprognostic (1.35e-2)" "unprognostic (1.84e-2)" "unprognostic (3.68e-2)" "unprognostic (2.53e-3)" "unprognostic (3.67e-3)" "unprognostic (2.22e-1)" "unprognostic (2.59e-3)" "unprognostic (3.99e-3)" "unprognostic (3.98e-3)" "unprognostic (1.28e-2)" "unprognostic (5.60e-2)" "unprognostic (3.46e-2)" "unprognostic (6.42e-3)" "unprognostic (5.18e-2)" "unprognostic (9.07e-2)" "unprognostic (1.60e-2)" "unprognostic (2.30e-1)" "unprognostic (7.35e-3)" "unprognostic (1.45e-1)" "unprognostic (2.09e-2)" "unprognostic (2.00e-1)" "unprognostic (7.61e-2)" "unprognostic (1.04e-1)" "unprognostic (1.75e-2)" ARPC2 "ARC34, p34-Arc" ENSG00000163466 "Actin related protein 2/3 complex subunit 2" O15144 2 218217141-218254356 "Essential proteins, Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 3043.0;Esophageal suprabasal cells: 2017.3;Extravillous trophoblasts: 2092.6;Neutrophils: 1912.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001994, HPA008352, HPA052703" Approved Supported Nucleoplasm NA NA 7600000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 29: Forebrain - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 81 Nucleoplasm "CAB001994: , HPA008352: , HPA052703: " "unprognostic (1.85e-1)" "potential prognostic unfavorable (5.24e-4)" "unprognostic (9.22e-2)" "unprognostic (4.53e-2)" "unprognostic (2.34e-1)" "unprognostic (2.80e-1)" "unprognostic (3.14e-2)" "unprognostic (3.68e-1)" "unprognostic (7.83e-2)" "unprognostic (1.19e-3)" "unprognostic (6.23e-3)" "unprognostic (3.16e-1)" "unprognostic (7.59e-3)" "potential prognostic unfavorable (1.42e-5)" "unprognostic (1.42e-2)" "unprognostic (3.67e-3)" "unprognostic (1.26e-2)" "unprognostic (5.56e-2)" "unprognostic (5.40e-2)" "unprognostic (2.52e-1)" "unprognostic (1.83e-1)" "unprognostic (3.57e-2)" "unprognostic (2.34e-2)" "unprognostic (1.30e-1)" "unprognostic (3.05e-1)" "unprognostic (1.82e-1)" "unprognostic (3.46e-3)" "unprognostic (1.73e-1)" "unprognostic (1.57e-1)" "unprognostic (7.93e-2)" "unprognostic (1.48e-1)" ARPC3 "ARC21, p21-Arc" ENSG00000111229 "Actin related protein 2/3 complex subunit 3" O15145 12 110434823-110450422 "Essential proteins, Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 692.8;Hofbauer cells: 571.9;Megakaryocytes: 574.9;Neutrophils: 514.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006550 Approved Uncertain Nucleoplasm NA NA 3100000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 38: Non-specific - Transcription" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 82 Nucleoplasm "HPA006550: " "unprognostic (1.25e-2)" "unprognostic (7.92e-2)" "unprognostic (2.97e-2)" "unprognostic (3.11e-2)" "unprognostic (7.45e-2)" "unprognostic (7.14e-2)" "unprognostic (4.94e-2)" "unprognostic (4.34e-1)" "unprognostic (5.32e-3)" "unprognostic (5.14e-3)" "validated prognostic unfavorable (4.88e-4)" "validated prognostic unfavorable (3.72e-5)" "unprognostic (2.31e-3)" "validated prognostic unfavorable (4.57e-4)" "validated prognostic unfavorable (5.07e-4)" "unprognostic (5.83e-3)" "unprognostic (1.01e-2)" "unprognostic (1.04e-1)" "unprognostic (1.85e-2)" "unprognostic (8.42e-2)" "unprognostic (1.24e-3)" "unprognostic (2.16e-3)" "unprognostic (4.72e-3)" "unprognostic (1.04e-1)" "unprognostic (2.43e-1)" "unprognostic (1.67e-1)" "unprognostic (6.96e-3)" "unprognostic (5.43e-2)" "unprognostic (1.81e-1)" "unprognostic (1.00e-1)" "unprognostic (3.34e-1)" ARPC4 "ARC20, p20-Arc" ENSG00000241553 "Actin related protein 2/3 complex subunit 4" P59998 3 9792495-9807101 "Essential proteins, Plasma proteins, Predicted intracellular proteins" Actin-binding "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 19.9;Brain inhibitory neurons: 17.6;Cardiomyocytes: 23.1;Megakaryocytes: 43.3;Microglia: 36.1;Oligodendrocytes: 20.9;Other brain neurons: 20.7;Platelets: 28.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 5100000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 22: Non-specific - Basic cellular functions" 46 "unprognostic (4.25e-3)" "unprognostic (6.49e-2)" "unprognostic (2.43e-2)" "unprognostic (4.68e-2)" "unprognostic (9.94e-2)" "unprognostic (5.49e-2)" "unprognostic (1.29e-1)" "unprognostic (1.71e-1)" "unprognostic (2.86e-1)" "unprognostic (1.55e-2)" "potential prognostic favorable (2.10e-5)" "unprognostic (2.82e-2)" "potential prognostic favorable (4.37e-7)" "validated prognostic unfavorable (7.16e-6)" "validated prognostic unfavorable (6.23e-7)" "unprognostic (3.76e-2)" "potential prognostic unfavorable (1.36e-4)" "unprognostic (1.34e-1)" "unprognostic (7.32e-2)" "unprognostic (7.05e-3)" "unprognostic (5.20e-2)" "unprognostic (3.04e-2)" "unprognostic (8.44e-2)" "unprognostic (2.32e-1)" "unprognostic (2.11e-1)" "unprognostic (2.16e-1)" "unprognostic (1.38e-1)" "unprognostic (2.79e-2)" "unprognostic (8.84e-2)" "unprognostic (8.39e-2)" "unprognostic (6.24e-2)" ARPC4-TTLL3 ENSG00000250151 "ARPC4-TTLL3 readthrough" 3 9793082-9835401 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Colonocytes: 22.6;Enteric stem cells: 15.5;Enteric transient amplifying cells: 17.2;Enterocytes: 13.6;Foveolar cells: 11.1;Goblet cells: 13.4;Megakaryocytes: 24.7;Neuroendocrine cells: 11.7;Neutrophil progenitors: 16.2;Neutrophils: 11.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 12: Non-specific - Vasculature" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 15: Non-specific - Protein processing" 3 "unprognostic (6.33e-2)" "unprognostic (1.53e-1)" "unprognostic (1.87e-3)" "unprognostic (9.99e-2)" "unprognostic (1.49e-1)" "unprognostic (1.29e-1)" "unprognostic (1.58e-1)" "unprognostic (4.01e-1)" "unprognostic (4.44e-2)" "potential prognostic favorable (6.81e-4)" "unprognostic (1.73e-2)" "unprognostic (7.94e-2)" "unprognostic (1.13e-1)" "unprognostic (8.09e-3)" "unprognostic (5.96e-2)" "unprognostic (1.83e-1)" "unprognostic (6.25e-2)" "unprognostic (2.82e-1)" "unprognostic (1.13e-1)" "potential prognostic unfavorable (1.59e-4)" "unprognostic (1.71e-2)" "unprognostic (1.85e-1)" "unprognostic (3.15e-1)" "unprognostic (7.35e-3)" "unprognostic (1.29e-1)" "unprognostic (3.15e-1)" "unprognostic (9.27e-2)" "unprognostic (2.83e-1)" ARPC5 "ARC16, dJ127C7.3, p16-Arc" ENSG00000162704 "Actin related protein 2/3 complex subunit 5" O15511 1 183620846-183635783 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 982.5;Extravillous trophoblasts: 967.1;Megakaryocytes: 2077.0;Neutrophil progenitors: 1259.2;Neutrophils: 1600.0;Platelets: 1465.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022013, HPA031972" Approved Approved "Vesicles,Plasma membrane,Cell Junctions,Cytosol" NA NA 1700000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 30: White matter - Myelination" "Cluster 55: Lymphoma - Immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 47 "Vesicles, Plasma membrane, Cell Junctions, Cytosol" "HPA022013: , HPA031972: " "unprognostic (9.11e-2)" "unprognostic (7.40e-2)" "unprognostic (2.74e-2)" "potential prognostic unfavorable (7.20e-4)" "unprognostic (9.97e-2)" "unprognostic (7.56e-2)" "unprognostic (1.09e-1)" "unprognostic (1.30e-1)" "unprognostic (2.03e-1)" "unprognostic (1.74e-2)" "potential prognostic favorable (1.33e-4)" "unprognostic (9.12e-2)" "unprognostic (1.48e-1)" "unprognostic (2.77e-2)" "unprognostic (8.04e-2)" "unprognostic (5.31e-3)" "unprognostic (2.45e-2)" "unprognostic (1.72e-2)" "unprognostic (1.17e-1)" "unprognostic (2.92e-2)" "unprognostic (1.26e-2)" "unprognostic (2.59e-2)" "unprognostic (2.18e-2)" "unprognostic (7.16e-2)" "unprognostic (1.12e-1)" "unprognostic (1.50e-2)" "unprognostic (6.26e-2)" "unprognostic (2.31e-1)" "unprognostic (3.07e-1)" "unprognostic (6.35e-2)" "unprognostic (1.39e-1)" ARPC5L "ARC16-2, MGC3038" ENSG00000136950 "Actin related protein 2/3 complex subunit 5 like" Q9BPX5 9 124862130-124877733 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 580.7;Esophageal apical cells: 792.4;Esophageal suprabasal cells: 457.8;Late primary spermatocytes: 496.5;Late spermatids: 1392.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022013 Approved NA NA 13000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 47 "HPA022013: " "unprognostic (5.02e-2)" "unprognostic (2.67e-2)" "unprognostic (1.63e-1)" "unprognostic (4.12e-1)" "unprognostic (1.11e-1)" "unprognostic (1.69e-3)" "unprognostic (4.02e-2)" "unprognostic (6.25e-3)" "unprognostic (1.85e-2)" "unprognostic (2.08e-1)" "unprognostic (1.76e-1)" "unprognostic (5.92e-2)" "unprognostic (4.63e-2)" "unprognostic (1.38e-3)" "potential prognostic unfavorable (3.47e-4)" "unprognostic (1.11e-3)" "unprognostic (7.00e-3)" "unprognostic (2.09e-1)" "unprognostic (1.06e-1)" "unprognostic (2.02e-1)" "unprognostic (1.91e-1)" "unprognostic (9.82e-2)" "unprognostic (2.34e-1)" "unprognostic (2.70e-1)" "unprognostic (1.35e-1)" "unprognostic (3.78e-1)" "unprognostic (4.34e-1)" "unprognostic (1.40e-1)" "unprognostic (1.30e-1)" "unprognostic (2.32e-2)" "unprognostic (2.97e-2)" ARPIN "C15orf38, MGC61550" ENSG00000242498 "Actin related protein 2/3 complex inhibitor" Q7Z6K5 15 89895006-89912952 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Late spermatids: 151.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 5.3;intermediate monocyte: 2.9;myeloid DC: 4.5" "Group enriched" "Detected in many" 7 "dendritic cells: 4.5;monocytes: 5.3" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040513, HPA047173, HPA052278" Uncertain NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 60: Stomach - Digestion" "Cluster 25: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 3 "HPA040513: , HPA047173: , HPA052278: " "unprognostic (2.53e-2)" "unprognostic (2.53e-1)" "unprognostic (9.18e-3)" "unprognostic (4.08e-1)" "unprognostic (2.45e-1)" "unprognostic (2.02e-2)" "potential prognostic unfavorable (2.63e-4)" "unprognostic (7.32e-2)" "unprognostic (1.28e-3)" "potential prognostic favorable (6.94e-6)" "unprognostic (1.04e-3)" "unprognostic (8.85e-3)" "unprognostic (3.66e-2)" "unprognostic (5.41e-2)" "unprognostic (1.27e-1)" "unprognostic (1.41e-1)" "unprognostic (1.13e-2)" "unprognostic (1.03e-2)" "unprognostic (4.09e-2)" "unprognostic (2.92e-2)" "unprognostic (3.04e-2)" "unprognostic (8.48e-2)" "unprognostic (1.21e-1)" "unprognostic (1.65e-1)" "unprognostic (3.44e-2)" "unprognostic (2.96e-2)" "unprognostic (9.32e-2)" "unprognostic (2.24e-1)" "unprognostic (1.84e-1)" ARPIN-AP3S2 C15orf38-AP3S2 ENSG00000250021 "ARPIN-AP3S2 readthrough" 15 89834308-89912882 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.7;Foveolar cells: 1.1;Myosatellite cells: 1.4;Respiratory deuterosomal cells: 2.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA040513, HPA047173, HPA049270, HPA052278" Uncertain Approved Vesicles NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 70: Non-specific - Protein processing" "Cluster 45: Non-specific - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" Vesicles "HPA040513: , HPA047173: , HPA049270: , HPA052278: " "unprognostic (3.30e-1)" "unprognostic (5.26e-2)" "unprognostic (5.58e-2)" "unprognostic (7.49e-2)" "unprognostic (7.00e-2)" "unprognostic (7.27e-2)" "unprognostic (1.55e-3)" "unprognostic (7.71e-2)" "unprognostic (8.37e-2)" "potential prognostic favorable (1.82e-5)" "unprognostic (3.93e-2)" "potential prognostic favorable (7.28e-4)" "unprognostic (1.42e-2)" "unprognostic (4.09e-2)" "unprognostic (5.73e-2)" "unprognostic (1.37e-1)" "unprognostic (2.78e-1)" "unprognostic (6.47e-3)" "unprognostic (3.97e-1)" "potential prognostic unfavorable (6.70e-4)" "unprognostic (3.36e-1)" "unprognostic (7.23e-2)" "unprognostic (5.82e-2)" "unprognostic (4.26e-1)" "unprognostic (1.07e-1)" "unprognostic (6.35e-2)" "unprognostic (2.56e-1)" "unprognostic (1.62e-1)" "unprognostic (8.69e-2)" ARPP19 "ARPP-16, ARPP-19, ARPP16, ENSAL" ENSG00000128989 "CAMP regulated phosphoprotein 19" P56211 15 52547045-52569883 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 481.4" "Cell type enriched" "Detected in all" 6 "Late spermatids: 5539.0" "Cell type enhanced" "Detected in all" "medium spiny neuron: 368.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056851 Approved Approved "Nucleoli,Vesicles,Basal body,Cytosol" NA NA 380000 "Cluster 45: Eosinophils - Unknown function" "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 3 "Vesicles, Basal body" "Nucleoli, Cytosol" "HPA056851: " "unprognostic (3.88e-2)" "unprognostic (1.09e-1)" "unprognostic (3.69e-1)" "unprognostic (8.37e-2)" "unprognostic (1.78e-1)" "unprognostic (4.93e-2)" "unprognostic (2.48e-1)" "unprognostic (1.45e-1)" "unprognostic (2.31e-1)" "unprognostic (6.41e-3)" "potential prognostic favorable (1.96e-8)" "unprognostic (2.32e-3)" "unprognostic (4.70e-1)" "unprognostic (7.41e-2)" "unprognostic (5.91e-3)" "unprognostic (5.49e-2)" "unprognostic (9.08e-2)" "unprognostic (2.92e-1)" "unprognostic (4.46e-2)" "unprognostic (9.76e-2)" "unprognostic (5.69e-2)" "unprognostic (7.72e-2)" "unprognostic (1.24e-1)" "unprognostic (2.89e-2)" "unprognostic (4.71e-2)" "unprognostic (6.29e-2)" "unprognostic (8.86e-2)" "unprognostic (1.77e-1)" "unprognostic (1.70e-1)" "unprognostic (2.04e-1)" "unprognostic (1.75e-2)" ARPP21 "ARPP-21, R3HDM3, TARPP" ENSG00000172995 "CAMP regulated phosphoprotein 21" Q9UBL0 3 35638945-35794496 "Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 746.4" "Cell type enhanced" "Detected in some" "Bergmann glia: 178.6;Brain excitatory neurons: 874.3;Brain inhibitory neurons: 608.3;Corticotrophs: 352.1;Myonuclei: 1018.6;Oligodendrocyte progenitor cells: 869.8;Oligodendrocytes: 217.4;Thymic myoid cells: 318.2;Thymocytes: 217.7" "Cell type enhanced" "Detected in all" "mammillary body: 2425.7" "Cancer enriched" "Detected in some" 7 "Glioblastoma Multiforme (TCGA): 9.9" "Region enhanced" "Detected in all" "basal ganglia: 619.4" "Immune cell enriched" "Detected in single" 30 "plasmacytoid DC: 9.9" "Lineage enriched" "Detected in single" 30 "dendritic cells: 9.9" "Cancer enriched" "Detected in some" 8 "Leukemia: 37.6" "Colon - Colon enteroendocrine cells, Pituitary gland - Corticotropes, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "basal ganglia: 1242.8" HPA017303 Enhanced Supported Approved Nucleoli,Cytosol NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" Nucleoli Cytosol "HPA017303: " "potential prognostic favorable (5.43e-4)" "unprognostic (1.33e-1)" "unprognostic (1.20e-3)" "unprognostic (1.39e-3)" "unprognostic (1.24e-3)" "unprognostic (1.69e-1)" ARR3 ARRX ENSG00000120500 "Arrestin 3" P36575 X 70268305-70281840 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 180 "retina: 357.5" "Cell type enriched" "Detected in some" 107 "Cone photoreceptor cells: 2322.7" "Low cell type specificity" "Detected in some" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Skin - Sebaceous gland cells" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA063129 Enhanced Approved "Golgi apparatus,Vesicles" NA NA "Cluster 42: Retina - Visual perception" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 1: Neuronal - Visual perception" "Cluster 79: Photoreceptor cells - Phototransduction" 13 "Golgi apparatus" Vesicles "HPA063129: " "unprognostic (1.98e-2)" "unprognostic (1.47e-2)" "unprognostic (7.13e-2)" ARRB1 ARR1 ENSG00000137486 "Arrestin beta 1" P49407 11 75260122-75351705 "Predicted intracellular proteins, Transporters" "Protein transport, Transcription, Transcription regulation, Transport" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 214.5;Kupffer cells: 177.3;Microglia: 162.0;Podocytes: 279.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 137.5" "Group enriched" "Detected in many" 5 "dendritic cells: 42.5;granulocytes: 49.7;monocytes: 137.5" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003763, HPA049318, HPA070249" Approved Supported Nucleoplasm NA NA 1900000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 73: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 120 Nucleoplasm "CAB003763: , HPA049318: , HPA070249: " "unprognostic (1.45e-1)" "unprognostic (8.91e-2)" "unprognostic (4.22e-1)" "unprognostic (2.98e-2)" "unprognostic (2.11e-1)" "unprognostic (1.24e-2)" "unprognostic (6.48e-2)" "unprognostic (1.20e-3)" "unprognostic (2.26e-3)" "unprognostic (9.58e-2)" "potential prognostic favorable (1.50e-7)" "unprognostic (1.12e-3)" "unprognostic (1.91e-1)" "unprognostic (3.43e-3)" "unprognostic (4.53e-2)" "potential prognostic favorable (3.34e-5)" "unprognostic (2.50e-1)" "unprognostic (2.10e-2)" "unprognostic (3.39e-1)" "unprognostic (1.89e-1)" "unprognostic (2.17e-1)" "unprognostic (3.83e-1)" "unprognostic (1.68e-1)" "unprognostic (2.53e-1)" "unprognostic (9.93e-2)" "unprognostic (3.10e-2)" "unprognostic (3.07e-1)" "unprognostic (4.07e-1)" "unprognostic (7.29e-2)" "unprognostic (1.46e-1)" "unprognostic (1.25e-1)" ARRB2 "ARR2, BARR2, DKFZp686L0365" ENSG00000141480 "Arrestin beta 2" P32121 17 4710596-4721499 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 249.0;lymphoid tissue: 157.8" "Cell type enhanced" "Detected in many" "cDC: 191.8;Hofbauer cells: 396.4;Kupffer cells: 251.1;Macrophages: 199.1;Microglia: 149.9;Monocyte progenitors: 134.9;monocytes: 334.4;Neutrophil progenitors: 241.3;Neutrophils: 933.6" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 188.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Heart muscle - Macrophages, Lung - Neutrophils_2, Minor Salivary Gland - Macrophages, Skeletal muscle - Macrophages, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075177 Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 114 "Plasma membrane, Cytosol" Nucleoplasm "HPA075177: " "unprognostic (9.10e-3)" "unprognostic (1.21e-1)" "unprognostic (1.18e-1)" "unprognostic (2.58e-2)" "unprognostic (3.11e-2)" "unprognostic (1.23e-1)" "unprognostic (1.03e-2)" "unprognostic (5.93e-2)" "unprognostic (4.29e-2)" "unprognostic (1.50e-2)" "unprognostic (4.34e-2)" "unprognostic (3.14e-1)" "unprognostic (1.39e-2)" "potential prognostic unfavorable (1.10e-4)" "unprognostic (2.71e-1)" "unprognostic (1.34e-3)" "unprognostic (1.66e-1)" "unprognostic (2.16e-2)" "unprognostic (2.76e-1)" "unprognostic (1.36e-1)" "unprognostic (9.51e-2)" "unprognostic (1.80e-2)" "unprognostic (7.87e-2)" "unprognostic (5.52e-3)" "unprognostic (4.48e-1)" "unprognostic (8.80e-2)" "unprognostic (7.63e-2)" "unprognostic (8.79e-2)" "unprognostic (6.41e-2)" "unprognostic (7.70e-2)" "unprognostic (7.19e-2)" ARRDC1 MGC40555 ENSG00000197070 "Arrestin domain containing 1" Q8N5I2 9 137605685-137615360 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 50.1;Esophageal apical cells: 51.3;Papillary tip epithelial cells: 57.1;Renal collecting duct principal cells: 59.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044345 Uncertain NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 23: Choroid plexus - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 22 "HPA044345: " "unprognostic (2.89e-1)" "unprognostic (8.32e-2)" "unprognostic (1.66e-1)" "unprognostic (1.20e-2)" "unprognostic (1.25e-2)" "unprognostic (6.78e-2)" "unprognostic (1.07e-3)" "unprognostic (2.09e-1)" "unprognostic (1.86e-1)" "unprognostic (1.76e-2)" "unprognostic (1.64e-1)" "unprognostic (1.79e-1)" "unprognostic (1.06e-3)" "unprognostic (1.25e-1)" "unprognostic (2.48e-1)" "unprognostic (1.99e-1)" "unprognostic (2.41e-1)" "unprognostic (1.50e-3)" "unprognostic (6.21e-2)" "unprognostic (6.54e-2)" "unprognostic (3.80e-2)" "unprognostic (1.48e-1)" "unprognostic (1.01e-1)" "unprognostic (4.82e-1)" "unprognostic (2.52e-1)" "unprognostic (3.11e-2)" "unprognostic (1.77e-1)" "unprognostic (2.92e-3)" "unprognostic (2.15e-1)" "unprognostic (1.29e-1)" "unprognostic (1.00e-1)" ARRDC2 "CLONE24945, PP2703" ENSG00000105643 "Arrestin domain containing 2" Q8TBH0 19 18001132-18014102 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 145.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 67.1;Conjunctival goblet cells: 98.1;Innate lymphoid cells: 61.4;Lymphatic endothelial cells: 58.0;Salivary duct cells: 107.3" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 42.2;leukocyte: 31.6;oligodendrocyte: 32.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053788, HPA074216" Uncertain Approved Nucleoplasm NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 6: Leukemia - Signal transduction" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 2 Nucleoplasm "HPA053788: , HPA074216: " "unprognostic (5.15e-3)" "unprognostic (7.32e-2)" "potential prognostic favorable (3.89e-5)" "unprognostic (3.51e-2)" "unprognostic (9.83e-2)" "unprognostic (1.63e-1)" "potential prognostic unfavorable (8.28e-4)" "unprognostic (7.93e-2)" "unprognostic (6.94e-3)" "unprognostic (3.47e-1)" "potential prognostic favorable (5.86e-4)" "unprognostic (1.21e-2)" "unprognostic (5.90e-3)" "unprognostic (8.00e-2)" "unprognostic (4.29e-2)" "unprognostic (3.54e-1)" "unprognostic (4.26e-2)" "unprognostic (2.76e-1)" "unprognostic (3.63e-1)" "potential prognostic unfavorable (2.44e-4)" "unprognostic (6.14e-3)" "unprognostic (2.29e-2)" "unprognostic (2.66e-2)" "unprognostic (1.92e-1)" "unprognostic (7.08e-2)" "unprognostic (1.07e-2)" "unprognostic (6.04e-3)" "unprognostic (7.82e-2)" "unprognostic (1.15e-1)" "unprognostic (2.60e-3)" "unprognostic (4.08e-1)" ARRDC3 "KIAA1376, TLIMP" ENSG00000113369 "Arrestin domain containing 3" Q96B67 5 91368631-91383317 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 500.8;Pancreatic acinar cells: 483.8;Syncytiotrophoblasts: 454.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 115.6" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA Yes "Cluster 4: Neutrophils - Degranulation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 53 "unprognostic (1.89e-2)" "unprognostic (9.77e-2)" "unprognostic (6.27e-2)" "unprognostic (7.94e-2)" "unprognostic (3.49e-2)" "unprognostic (9.01e-2)" "unprognostic (2.43e-2)" "unprognostic (1.95e-3)" "unprognostic (1.18e-1)" "unprognostic (6.59e-3)" "unprognostic (2.87e-1)" "unprognostic (1.07e-1)" "unprognostic (3.76e-2)" "unprognostic (2.21e-3)" "unprognostic (3.28e-1)" "unprognostic (2.13e-2)" "unprognostic (1.30e-2)" "unprognostic (1.15e-1)" "unprognostic (6.32e-3)" "unprognostic (3.17e-3)" "unprognostic (4.02e-2)" "unprognostic (8.61e-2)" "unprognostic (1.08e-2)" "unprognostic (1.29e-1)" "unprognostic (1.00e-3)" "unprognostic (1.44e-2)" "unprognostic (2.37e-1)" "unprognostic (1.10e-2)" "unprognostic (4.70e-2)" "unprognostic (1.27e-1)" "unprognostic (4.02e-1)" ARRDC4 FLJ36045 ENSG00000140450 "Arrestin domain containing 4" Q8NCT1 15 97960703-97973833 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 75.7" "Cell type enhanced" "Detected in many" "Colonocytes: 84.6;Epididymal principal cells: 122.5;Parietal cells: 132.6;Podocytes: 243.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 1.1;classical monocyte: 2.5;eosinophil: 1.5;intermediate monocyte: 1.7;myeloid DC: 1.1;neutrophil: 1.4" "Group enriched" "Detected in many" 8 "dendritic cells: 1.1;granulocytes: 1.5;monocytes: 2.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039934, HPA042109" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 22: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 4 "Plasma membrane" Vesicles "HPA039934: , HPA042109: " "unprognostic (3.64e-2)" "unprognostic (7.71e-2)" "unprognostic (2.82e-3)" "unprognostic (2.14e-3)" "unprognostic (2.81e-2)" "unprognostic (7.53e-2)" "unprognostic (1.98e-3)" "potential prognostic unfavorable (5.16e-4)" "unprognostic (9.77e-2)" "unprognostic (9.36e-2)" "unprognostic (5.45e-3)" "unprognostic (4.10e-1)" "unprognostic (7.71e-2)" "unprognostic (1.11e-2)" "potential prognostic favorable (5.98e-8)" "unprognostic (3.07e-1)" "unprognostic (1.45e-1)" "unprognostic (1.48e-1)" "unprognostic (1.40e-1)" "unprognostic (1.44e-1)" "unprognostic (1.14e-1)" "unprognostic (2.38e-2)" "unprognostic (2.67e-2)" "unprognostic (7.26e-3)" "unprognostic (1.55e-1)" "unprognostic (7.93e-2)" "unprognostic (8.56e-2)" "unprognostic (4.83e-2)" "unprognostic (8.51e-2)" "unprognostic (1.83e-2)" "unprognostic (4.53e-2)" ARRDC5 ENSG00000205784 "Arrestin domain containing 5" A6NEK1 19 4890437-4902896 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 16.1" "Cell type enhanced" "Detected in some" "Early spermatids: 291.3;Late primary spermatocytes: 167.2;Late spermatids: 64.6;Microglia: 23.4;Neutrophil progenitors: 46.1;pDCs: 27.7;Thymocytes: 30.5" "Group enriched" "Detected in some" 40 "central nervous system macrophage: 28.3;leukocyte: 23.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Prostate - T-cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 39: Testis - Nuclear processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 6: Leukemia - Signal transduction" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 1 "unprognostic (5.54e-2)" "unprognostic (5.94e-2)" "unprognostic (1.40e-2)" "unprognostic (5.93e-3)" ARSA ASA ENSG00000100299 "Arylsulfatase A" P15289 22 50622754-50628173 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" Hydrolase "Disease variant, Ichthyosis, Leukodystrophy, Metachromatic leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 85.3;Enterocytes: 90.4;Fallopian tube ciliated cells: 103.1;Late primary spermatocytes: 84.5;Late spermatids: 215.5;Plasma cells: 85.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005554, CAB025183" Enhanced Uncertain "Golgi apparatus,Cytosol,Mid piece" "Intracellular and membrane" Enzyme NA NA 2400000 "Cluster 7: Non-specific - Innate immune response" "Cluster 70: Non-specific - Protein processing" "Cluster 12: Non-specific - Vasculature" "Cluster 66: Non-specific - Mitochondria" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 37 "Golgi apparatus" "Cytosol, Mid piece" "CAB025183: , HPA005554: " "unprognostic (1.79e-1)" "unprognostic (1.99e-1)" "unprognostic (2.84e-1)" "unprognostic (1.00e-2)" "unprognostic (3.21e-1)" "unprognostic (2.60e-2)" "unprognostic (1.21e-1)" "unprognostic (5.38e-2)" "unprognostic (1.79e-1)" "unprognostic (3.28e-1)" "unprognostic (5.16e-2)" "unprognostic (1.72e-2)" "potential prognostic favorable (1.10e-4)" "unprognostic (1.24e-2)" "unprognostic (7.83e-3)" "unprognostic (7.24e-2)" "unprognostic (1.51e-1)" "unprognostic (9.12e-2)" "unprognostic (1.65e-1)" "unprognostic (8.82e-2)" "unprognostic (1.52e-1)" "unprognostic (5.25e-2)" "unprognostic (7.38e-2)" "unprognostic (2.05e-1)" "unprognostic (2.49e-2)" "unprognostic (8.02e-2)" "unprognostic (5.63e-2)" "unprognostic (2.66e-2)" "unprognostic (1.01e-1)" "unprognostic (1.27e-1)" "unprognostic (6.41e-3)" ARSB ASB ENSG00000113273 "Arylsulfatase B" P15848 5 78777209-78986087 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant, Ichthyosis, Leukodystrophy, Metachromatic leukodystrophy, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Kupffer cells: 134.3;Microglia: 145.3;Neutrophil progenitors: 138.6;Oligodendrocyte progenitor cells: 133.6;Proximal tubule cells: 232.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 25.5" "Group enriched" "Detected in many" 7 "dendritic cells: 7.8;granulocytes: 25.5;monocytes: 8.3" "Low cancer specificity" "Detected in all" "Adipose visceral - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037770, HPA037771" Approved Approved "Golgi apparatus" "Intracellular and membrane" Enzyme NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 72: Kidney - Transmembrane transport" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 88: Proximal tubular cells - Transmembrane transport" 3 "Golgi apparatus" "HPA037770: , HPA037771: " "unprognostic (2.08e-1)" "unprognostic (3.13e-1)" "unprognostic (3.28e-1)" "unprognostic (1.91e-2)" "unprognostic (1.05e-1)" "unprognostic (1.49e-1)" "unprognostic (9.88e-2)" "unprognostic (5.71e-2)" "unprognostic (3.62e-1)" "unprognostic (1.79e-2)" "potential prognostic favorable (1.40e-6)" "unprognostic (2.18e-2)" "unprognostic (1.90e-1)" "unprognostic (6.08e-2)" "unprognostic (1.11e-1)" "unprognostic (1.78e-2)" "potential prognostic unfavorable (9.20e-4)" "unprognostic (1.02e-2)" "unprognostic (8.13e-2)" "unprognostic (4.64e-2)" "unprognostic (4.70e-3)" "unprognostic (4.83e-2)" "unprognostic (1.05e-1)" "unprognostic (1.33e-1)" "unprognostic (1.10e-1)" "unprognostic (2.02e-2)" "unprognostic (9.85e-2)" "unprognostic (4.97e-3)" "unprognostic (1.87e-1)" "potential prognostic unfavorable (3.30e-4)" "unprognostic (4.22e-2)" ARSD ASD ENSG00000006756 "Arylsulfatase D" P51689 X 2903972-2929349 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 149.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Breast glandular cells, Breast - Breast glandular cells, Liver - Hepatocytes, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "HPA004694, HPA063835" Approved Approved "Vesicles,Lipid droplets" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 60: Stomach - Digestion" "Cluster 8: Immune cells - Immune response" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" "Vesicles, Lipid droplets" "HPA004694: , HPA063835: " "unprognostic (6.31e-2)" "unprognostic (4.99e-2)" "unprognostic (3.29e-1)" "unprognostic (8.10e-3)" "unprognostic (9.74e-2)" "unprognostic (7.19e-2)" "unprognostic (3.83e-3)" "potential prognostic unfavorable (5.56e-6)" "unprognostic (9.54e-2)" "unprognostic (2.55e-1)" "potential prognostic favorable (4.21e-6)" "unprognostic (1.41e-2)" "potential prognostic favorable (3.71e-5)" "unprognostic (7.47e-3)" "unprognostic (1.08e-2)" "unprognostic (1.53e-1)" "unprognostic (3.86e-1)" "unprognostic (6.37e-2)" "unprognostic (1.76e-1)" "unprognostic (6.05e-2)" "unprognostic (5.44e-2)" "unprognostic (3.80e-2)" "unprognostic (2.45e-2)" "unprognostic (4.34e-1)" "unprognostic (1.76e-1)" "unprognostic (2.61e-2)" "unprognostic (1.78e-1)" "unprognostic (1.17e-1)" "unprognostic (6.74e-2)" "unprognostic (1.19e-1)" "unprognostic (1.49e-2)" ARSF ASF ENSG00000062096 "Arylsulfatase F" P54793 X 3041471-3112727 "Enzymes, Predicted membrane proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.8;kidney: 7.1;skin 1: 5.3" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 42.5;Astrocytes: 21.1;Esophageal apical cells: 10.9;Esophageal suprabasal cells: 9.7;Oligodendrocyte progenitor cells: 5.2;Proximal tubule cells: 38.3" "Cell type enhanced" "Detected in many" "astrocyte: 26.6;CGE interneuron: 17.4" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 5.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adrenal gland - Adrenal medulla cells, Kidney - Proximal tubular cells" "Not detected" "Not detected" HPA000549 Approved Vesicles,Cytosol "Secreted in other tissues" Enzyme NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 88: Proximal tubular cells - Transmembrane transport" 2 "Vesicles, Cytosol" "HPA000549: " "unprognostic (2.32e-2)" "unprognostic (7.19e-3)" "unprognostic (1.26e-3)" "validated prognostic favorable (3.42e-6)" "validated prognostic favorable (3.88e-4)" "unprognostic (6.34e-3)" "unprognostic (2.85e-2)" "unprognostic (5.21e-3)" ARSG KIAA1001 ENSG00000141337 "Arylsulfatase G" Q96EG1 17 68259182-68422731 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Hydrolase "Deafness, Disease variant, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 28.6" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 174.5;Endometrial glandular cells: 92.5;Epididymal principal cells: 117.1;monocytes: 114.3;Neutrophils: 286.9;Retinal ganglion cells: 108.2;Rod photoreceptor cells: 161.3" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 194.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023245, HPA023285" Enhanced "Intracellular and membrane" Enzyme NA NA 230000 "Cluster 35: Neutrophils - Protein binding" "Cluster 22: Epididymis - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 24: Neutrophils - Innate immunity signal integration" 5 "HPA023245: , HPA023285: " "unprognostic (2.76e-3)" "unprognostic (1.56e-1)" "unprognostic (6.00e-2)" "unprognostic (9.58e-2)" "unprognostic (8.57e-2)" "unprognostic (1.44e-2)" "unprognostic (1.10e-1)" "unprognostic (2.11e-1)" "unprognostic (5.43e-2)" "unprognostic (2.73e-2)" "potential prognostic favorable (1.93e-5)" "unprognostic (1.43e-1)" "unprognostic (2.18e-3)" "unprognostic (2.15e-1)" "unprognostic (1.53e-2)" "unprognostic (6.55e-3)" "unprognostic (1.40e-1)" "unprognostic (1.91e-1)" "unprognostic (1.82e-2)" "unprognostic (2.58e-1)" "unprognostic (1.80e-1)" "potential prognostic favorable (8.75e-7)" "unprognostic (3.31e-2)" "unprognostic (1.29e-1)" "unprognostic (1.32e-1)" "unprognostic (1.83e-1)" "unprognostic (1.60e-1)" "unprognostic (6.85e-2)" "unprognostic (4.10e-1)" "unprognostic (8.46e-2)" "unprognostic (8.98e-2)" ARSH ENSG00000205667 "Arylsulfatase family member H" Q5FYA8 X 3006546-3034111 "Predicted membrane proteins" Hydrolase "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Breast hormone-responsive cells: 2.0;Breast secretory cells: 1.4;Epicardial cells: 2.3;Epididymal principal cells: 4.5;Esophageal apical cells: 5.6;Esophageal suprabasal cells: 2.9;Platelets: 2.8;Syncytiotrophoblasts: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Breast glandular cells, Breast - Breast glandular cells, Skin - Hair cortex cells, Skin - Inner root sheath cells" NA NA "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" "unprognostic (2.87e-1)" ARSI "FLJ16069, SPG66" ENSG00000183876 "Arylsulfatase family member I" Q5FYB1 5 150296343-150339307 "Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 17.5;Hepatic stellate cells: 25.8;Mast cells: 34.5;Melanocytes: 29.4;Oligodendrocytes: 17.5;pDCs: 25.1;Proximal tubule cells: 34.7;Suprabasal keratinocytes: 11.9" "Cell type enriched" "Detected in some" 5 "oligodendrocyte: 35.0" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 17.0;Skin Cutaneous Melanoma (TCGA): 17.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 33.8" "Colon - Enteric glia cells, Prostate - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" "HPA038386, HPA038398, HPA077833" Uncertain Approved "Golgi apparatus,Vesicles" "Secreted in other tissues" Enzyme NA NA "Cluster 68: Non-specific - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 108: Fibroblasts - ECM organization" 1 "Golgi apparatus" Vesicles "HPA038386: , HPA038398: , HPA077833: " "unprognostic (6.05e-2)" "unprognostic (9.70e-3)" "unprognostic (1.37e-1)" "unprognostic (3.97e-2)" "unprognostic (7.95e-3)" "unprognostic (2.32e-1)" "unprognostic (8.53e-3)" "potential prognostic unfavorable (7.84e-4)" "unprognostic (6.36e-3)" "unprognostic (2.21e-2)" "unprognostic (1.33e-3)" "unprognostic (4.01e-2)" "unprognostic (1.77e-2)" "unprognostic (1.78e-3)" "unprognostic (1.34e-3)" "unprognostic (9.05e-3)" "unprognostic (8.26e-3)" "unprognostic (1.79e-2)" "unprognostic (6.89e-2)" "unprognostic (1.69e-2)" "unprognostic (1.14e-1)" "unprognostic (3.86e-1)" ARSJ FLJ23548 ENSG00000180801 "Arylsulfatase family member J" Q5FYB0 4 113900284-113979727 "Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 110.2;Endometrial stromal cells: 85.3;Medullary thymic epithelial cells: 79.2;Renal collecting duct intercalated cells: 165.8;Renal collecting duct principal cells: 84.4;Renal connecting tubule cells: 101.2;Salivary ionocytes: 130.6" "Cell type enhanced" "Detected in many" "deep-layer corticothalamic and 6b: 107.0;upper rhombic lip: 139.7" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 16.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast myoepithelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA036481, HPA036482" Uncertain Enhanced "Actin filaments" "Secreted in other tissues" Enzyme NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 15: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" "Actin filaments" "HPA036481: , HPA036482: " "unprognostic (1.73e-3)" "unprognostic (1.25e-1)" "unprognostic (1.00e-1)" "potential prognostic unfavorable (1.16e-4)" "unprognostic (3.03e-1)" "unprognostic (1.28e-1)" "unprognostic (5.75e-2)" "potential prognostic unfavorable (1.15e-5)" "potential prognostic unfavorable (4.63e-4)" "unprognostic (1.14e-3)" "potential prognostic favorable (1.94e-4)" "unprognostic (8.37e-2)" "unprognostic (7.30e-2)" "unprognostic (2.69e-2)" "unprognostic (1.93e-1)" "unprognostic (1.01e-3)" "unprognostic (1.89e-1)" "unprognostic (1.67e-2)" "unprognostic (8.71e-2)" "potential prognostic unfavorable (2.99e-4)" "unprognostic (3.12e-2)" "unprognostic (1.24e-1)" "unprognostic (3.48e-1)" "unprognostic (2.09e-1)" "unprognostic (2.37e-1)" "unprognostic (5.07e-2)" "unprognostic (3.15e-1)" "unprognostic (1.80e-1)" ARSK "DKFZp313G1735, TSULF" ENSG00000164291 "Arylsulfatase family member K" Q6UWY0 5 95555101-95605102 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins" Hydrolase "Disease variant, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 18.0" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 88.1;Prostatic glandular cells: 48.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Macrophages, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042384 Approved Approved Nucleoplasm,Vesicles "Secreted in other tissues" Enzyme NA NA "Cluster 24: Non-specific - Transcription" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 69: Skin cancer - ECM organization" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 27 Vesicles Nucleoplasm "HPA042384: " "unprognostic (3.83e-1)" "unprognostic (3.56e-1)" "unprognostic (2.97e-1)" "unprognostic (3.05e-2)" "unprognostic (7.20e-3)" "unprognostic (2.74e-1)" "unprognostic (1.83e-2)" "unprognostic (6.49e-3)" "unprognostic (3.47e-1)" "potential prognostic unfavorable (9.77e-4)" "potential prognostic favorable (1.09e-4)" "unprognostic (1.75e-1)" "unprognostic (3.13e-1)" "potential prognostic unfavorable (3.62e-4)" "unprognostic (1.18e-1)" "unprognostic (3.10e-2)" "unprognostic (4.08e-2)" "unprognostic (2.25e-1)" "unprognostic (2.16e-2)" "unprognostic (8.59e-2)" "unprognostic (7.98e-3)" "unprognostic (8.15e-2)" "unprognostic (1.10e-3)" "unprognostic (2.85e-1)" "unprognostic (6.39e-2)" "unprognostic (4.20e-1)" "unprognostic (3.64e-1)" "unprognostic (1.70e-2)" "unprognostic (7.41e-2)" "unprognostic (2.87e-2)" "unprognostic (1.70e-1)" ARSL "ARSE, CDPX, CDPX1" ENSG00000157399 "Arylsulfatase L" P51690 X 2934045-2968475 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 34.2;liver: 85.2;pancreas: 99.1" "Cell type enhanced" "Detected in many" "Cholangiocytes: 35.1;Colonocytes: 51.3;Enteric stem cells: 105.8;Enteric transient amplifying cells: 79.8;Enterocytes: 48.9;Epididymal clear cells: 38.8;Epididymal efferent duct absorptive cells: 110.3;Hepatocytes: 108.6;Pancreatic acinar cells: 79.6;Pancreatic duct cells: 70.2;Paneth cells: 77.3;Schwann cells: 33.6" "Cell type enhanced" "Detected in many" "fibroblast: 22.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 30.8;liver cancer: 33.4" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Kidney - Proximal tubular cells, Lung - Alveolar cells type 2, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "HPA060518, HPA070651" Approved Supported "Golgi apparatus" NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 44: Non-specific - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" "Golgi apparatus" "HPA060518: , HPA070651: " "unprognostic (3.76e-2)" "unprognostic (2.15e-1)" "unprognostic (1.02e-1)" "unprognostic (4.75e-3)" "unprognostic (1.11e-2)" "unprognostic (1.42e-2)" "potential prognostic unfavorable (2.41e-5)" "unprognostic (1.10e-1)" "unprognostic (1.81e-1)" "potential prognostic favorable (1.56e-4)" "unprognostic (5.03e-2)" "unprognostic (2.25e-1)" "unprognostic (4.00e-1)" "unprognostic (7.45e-2)" "unprognostic (9.06e-2)" "unprognostic (2.46e-2)" "unprognostic (1.39e-1)" "unprognostic (1.74e-1)" "unprognostic (2.87e-1)" "unprognostic (1.42e-3)" "unprognostic (9.09e-2)" "unprognostic (7.56e-2)" "unprognostic (1.30e-2)" "unprognostic (8.45e-2)" "unprognostic (1.08e-1)" "unprognostic (5.85e-2)" ART1 "ART2, ARTC1, CD296" ENSG00000129744 "ADP-ribosyltransferase 1" P52961 11 3645128-3664416 "CD markers, Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 56 "skeletal muscle: 44.4;tongue: 34.3" "Group enriched" "Detected in some" 16 "Myonuclei: 90.4;Thymic myoid cells: 24.5" "Cell type enriched" "Detected in single" 21 "endothelial cell: 6.4" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA051148 Uncertain NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 15: Non-specific - Transcription" "Cluster 70: DU4475 - Unknown function" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" "HPA051148: " ART3 ARTC3 ENSG00000156219 "ADP-ribosyltransferase 3 (inactive)" Q13508 4 76011184-76114048 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "heart muscle: 63.7;skeletal muscle: 190.7;testis: 86.3;tongue: 70.8" "Group enriched" "Detected in many" 4 "Early primary spermatocytes: 266.6;Late primary spermatocytes: 182.9;Myonuclei: 527.5;Thymic myoid cells: 504.4" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 78.3;upper-layer intratelencephalic: 52.6" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 8.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "breast cancer: 6.9;skin cancer: 17.6" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA011268 Enhanced Approved "Principal piece,End piece" "Intracellular and membrane" Enzyme NA NA 16000000 "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 53: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" "Principal piece, End piece" "HPA011268: " "unprognostic (2.29e-1)" "unprognostic (1.77e-1)" "unprognostic (5.63e-2)" "unprognostic (2.45e-2)" "unprognostic (1.29e-1)" "unprognostic (3.76e-3)" "unprognostic (1.82e-1)" "unprognostic (1.48e-2)" "unprognostic (2.36e-1)" "unprognostic (2.33e-1)" "unprognostic (1.41e-1)" ART4 "ARTC4, CD297, DO, DOK1" ENSG00000111339 "ADP-ribosyltransferase 4 (inactive) (Dombrock blood group)" Q93070 12 14825569-14843526 "Blood group antigen proteins, CD markers, Enzymes, Metabolic proteins, Predicted membrane proteins, Predicted secreted proteins" "Blood group antigen, Glycosyltransferase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 49.7;lymphoid tissue: 17.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 26.5;Cholangiocytes: 23.6;Cone photoreceptor cells: 18.6;Erythrocyte progenitors: 41.2;Hepatic stellate cells: 77.5;Hepatocytes: 86.1;Lymphatic endothelial cells: 108.3;Rod photoreceptor cells: 28.6" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Liver Hepatocellular Carcinoma (TCGA): 8.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Rhabdoid: 11.7" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Fibroblasts, Liver - Hepatocytes, Thyroid gland - Fibroblasts" "Region enhanced" "Detected in single" "olfactory bulb: 1.8" "Low region specificity" "Detected in all" HPA075664 Approved "Rods & Rings" "Secreted to blood" Enzyme NA NA 2500000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "Rods & Rings" "HPA075664: " "unprognostic (1.20e-1)" "unprognostic (1.38e-1)" "potential prognostic favorable (1.48e-4)" "potential prognostic favorable (7.63e-4)" "unprognostic (3.78e-2)" "unprognostic (2.76e-1)" "unprognostic (1.08e-3)" "unprognostic (1.32e-2)" "unprognostic (5.38e-2)" "unprognostic (1.37e-1)" "unprognostic (1.26e-1)" "unprognostic (1.56e-1)" ART5 ARTC5 ENSG00000167311 "ADP-ribosyltransferase 5" Q96L15 11 3638512-3642316 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Glycosyltransferase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 11.1;skeletal muscle: 12.6;testis: 28.7" "Cell type enriched" "Detected in some" 4 "Late primary spermatocytes: 118.1" "Cell type enhanced" "Detected in single" "endothelial cell: 2.7" "Group enriched" "Detected in many" 4 "Kidney Chromophobe (TCGA): 9.7;Testicular Germ Cell Tumor (TCGA): 10.9" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "testis cancer: 12.7" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041637, HPA044099" Uncertain "Secreted in other tissues" Enzyme NA NA "Cluster 75: Ovary - Mixed function" "Cluster 44: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 1 "HPA041637: , HPA044099: " "unprognostic (1.39e-1)" "unprognostic (2.11e-1)" "unprognostic (3.06e-3)" "unprognostic (3.13e-1)" "unprognostic (1.01e-2)" "unprognostic (8.22e-2)" "unprognostic (1.64e-1)" "unprognostic (1.51e-1)" "unprognostic (4.49e-2)" "unprognostic (1.24e-1)" "unprognostic (2.75e-2)" "unprognostic (1.82e-2)" ARTN "ENOVIN, EVN, NBN" ENSG00000117407 Artemin Q5T4W7 1 43933320-43937240 "Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 10.6;Breast lactating cells: 15.2;Early spermatids: 6.7;Endometrial secretory cells: 6.8;Gonadotrophs: 6.3;Hematopoietic stem cells: 5.3;Late primary spermatocytes: 11.4;Ocular epithelial cells: 16.0;Prostatic hillock cells: 5.7;Salivary duct cells: 8.4;Schwann cells: 6.0;Vascular smooth muscle cells: 15.5" "Group enriched" "Detected in many" 5 "lower rhombic lip: 15.5;thalamic excitatory: 5.8" "Cancer enhanced" "Detected in many" "Lung Squamous Cell Carcinoma (TCGA): 31.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Esophageal cancer: 47.6;head and neck cancer: 57.7" "Adipose subcutaneous - Smooth muscle cells" "Region enriched" "Detected in single" 9 "olfactory bulb: 3.3" "Region enriched" "Detected in single" 5 "olfactory bulb: 3.5" "Secreted in other tissues" "Growth factor" NA NA "Cluster 20: Pituitary gland - Hormone signaling" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 1 "unprognostic (1.20e-1)" "unprognostic (8.91e-2)" "unprognostic (2.39e-1)" "unprognostic (2.73e-2)" "unprognostic (6.90e-2)" "unprognostic (1.76e-2)" "unprognostic (1.33e-1)" "unprognostic (1.52e-2)" "unprognostic (2.97e-1)" "potential prognostic unfavorable (1.81e-8)" "unprognostic (9.15e-3)" "unprognostic (2.63e-3)" "unprognostic (6.87e-2)" "unprognostic (2.21e-1)" "unprognostic (1.45e-1)" "unprognostic (6.79e-2)" "unprognostic (2.46e-3)" "unprognostic (1.24e-1)" "unprognostic (1.66e-1)" "unprognostic (1.71e-1)" "unprognostic (5.17e-2)" "unprognostic (5.25e-2)" "unprognostic (1.14e-1)" "unprognostic (1.91e-2)" "unprognostic (7.18e-2)" "unprognostic (1.55e-3)" "unprognostic (1.43e-2)" ARV1 ENSG00000173409 "ARV1 homolog, fatty acid homeostasis modulator" Q9H2C2 1 230978981-231000733 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 211.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035709 Approved Uncertain Vesicles NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 76: Non-specific - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 13 Vesicles "HPA035709: " "unprognostic (3.31e-3)" "unprognostic (4.62e-2)" "unprognostic (1.36e-1)" "unprognostic (2.46e-2)" "unprognostic (2.05e-3)" "unprognostic (5.07e-3)" "unprognostic (1.04e-1)" "unprognostic (3.48e-2)" "unprognostic (1.50e-1)" "unprognostic (2.56e-2)" "potential prognostic favorable (8.07e-8)" "unprognostic (4.40e-2)" "unprognostic (1.81e-1)" "unprognostic (3.71e-2)" "unprognostic (2.15e-2)" "unprognostic (1.39e-1)" "unprognostic (1.65e-2)" "potential prognostic favorable (1.36e-4)" "unprognostic (7.28e-2)" "unprognostic (2.36e-2)" "unprognostic (1.86e-1)" "unprognostic (4.58e-2)" "unprognostic (1.18e-1)" "unprognostic (1.21e-1)" "unprognostic (3.99e-2)" "unprognostic (2.16e-2)" "unprognostic (7.94e-2)" "unprognostic (3.43e-1)" "unprognostic (2.97e-2)" "unprognostic (2.92e-1)" "unprognostic (2.81e-1)" ARVCF ENSG00000099889 "ARVCF delta catenin family member" O00192 22 19969896-20016823 "Predicted intracellular proteins" "Cell adhesion, mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 52.5" "Cell type enhanced" "Detected in many" "Astrocytes: 36.6;Epididymal principal cells: 126.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 27.0" "Colon - Enteric glia cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016162, HPA055264, HPA063675" Enhanced Enhanced "Plasma membrane,Cell Junctions" NA NA "Cluster 64: Non-specific - Transcription" "Cluster 35: Non-specific - DNA binding" "Cluster 54: Non-specific - Transcription" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 4 "Plasma membrane, Cell Junctions" "CAB016162: , HPA055264: , HPA063675: " "unprognostic (8.66e-2)" "unprognostic (1.42e-1)" "unprognostic (1.91e-2)" "unprognostic (1.80e-2)" "unprognostic (7.27e-2)" "unprognostic (1.35e-3)" "unprognostic (2.61e-1)" "potential prognostic favorable (7.22e-4)" "unprognostic (7.34e-2)" "unprognostic (3.57e-2)" "potential prognostic favorable (1.91e-7)" "unprognostic (4.38e-3)" "potential prognostic favorable (8.97e-5)" "unprognostic (6.33e-2)" "unprognostic (7.63e-2)" "potential prognostic favorable (8.29e-4)" "unprognostic (1.41e-2)" "unprognostic (3.12e-2)" "unprognostic (7.35e-2)" "unprognostic (1.32e-3)" "unprognostic (2.74e-3)" "unprognostic (1.27e-1)" "potential prognostic favorable (5.17e-4)" "unprognostic (1.03e-3)" "unprognostic (2.53e-1)" "unprognostic (9.93e-3)" "unprognostic (3.44e-1)" "unprognostic (8.00e-2)" "unprognostic (4.72e-2)" ARX "CT121, EIEE1, ISSX, MRX29, MRX32, MRX33, MRX36, MRX38, MRX43, MRX54, MRX76, MRX87, MRXS1, PRTS" ENSG00000004848 "Aristaless related homeobox" Q96QS3 X 25003694-25016420 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant, Epilepsy, Intellectual disability, Lissencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "ovary: 77.7;skeletal muscle: 25.0" "Cell type enhanced" "Detected in some" "Brain inhibitory neurons: 25.9;Ependymal cells: 28.7;Leydig cells: 250.4;Myonuclei: 46.6;Neuroendocrine cells: 75.3;Oocytes: 27.6;Ovarian stromal cells: 84.6;Pancreatic islet cells: 64.2;Peritubular myoid cells: 109.1;Respiratory ciliated cells: 35.1" "Cell type enhanced" "Detected in some" "CGE interneuron: 50.4;LAMP5-LHX6 and Chandelier: 91.1;MGE interneuron: 113.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Bone cancer: 15.5" "Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 94: Gonadal somatic cells - Mixed function" 7 "unprognostic (2.57e-2)" "unprognostic (1.42e-1)" "unprognostic (1.14e-2)" "unprognostic (1.66e-1)" "unprognostic (1.88e-1)" "potential prognostic unfavorable (9.17e-4)" "unprognostic (1.35e-1)" "unprognostic (2.55e-1)" "unprognostic (4.01e-1)" "unprognostic (2.28e-3)" "unprognostic (1.24e-1)" "unprognostic (7.35e-3)" "unprognostic (2.45e-1)" "unprognostic (1.68e-1)" "unprognostic (6.86e-2)" "potential prognostic unfavorable (5.28e-4)" AS3MT CYT19 ENSG00000214435 "Arsenite methyltransferase" Q9HBK9 10 102869470-102901899 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "adrenal gland: 260.6" "Cell type enhanced" "Detected in some" "Astrocytes: 13.8;Bergmann glia: 6.8;Brain excitatory neurons: 14.0;Brain inhibitory neurons: 13.8;Choroid plexus epithelial cells: 22.7;Ependymal cells: 15.9;Microglia: 3.3;Oligodendrocyte progenitor cells: 8.6;Oligodendrocytes: 7.3;Other brain neurons: 12.7" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 43.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Minor Salivary Gland - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017856 Enhanced Approved Mitochondria NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 18: Liver cancer - Metabolism" "Cluster 98: Neurons - Neurotransmission & signaling" Mitochondria "HPA017856: " "unprognostic (3.82e-1)" "unprognostic (2.30e-1)" "unprognostic (8.96e-2)" "unprognostic (3.25e-1)" "unprognostic (3.53e-2)" "unprognostic (1.06e-1)" "unprognostic (3.25e-1)" "unprognostic (2.81e-1)" "unprognostic (9.63e-2)" "potential prognostic favorable (3.22e-4)" "unprognostic (3.89e-3)" "potential prognostic favorable (5.52e-5)" "unprognostic (3.07e-2)" "unprognostic (1.86e-1)" "unprognostic (1.55e-1)" "unprognostic (9.17e-2)" "unprognostic (1.88e-1)" "unprognostic (5.64e-2)" "unprognostic (2.42e-1)" "unprognostic (1.25e-1)" "unprognostic (5.16e-1)" "unprognostic (4.04e-3)" "unprognostic (1.67e-1)" "unprognostic (1.13e-1)" "unprognostic (1.70e-1)" "unprognostic (1.43e-1)" "unprognostic (3.23e-2)" "unprognostic (1.17e-1)" "unprognostic (2.10e-1)" "unprognostic (4.85e-3)" ASAH1 "AC, ACDase, ASAH, FLJ21558, PHP32" ENSG00000104763 "N-acylsphingosine amidohydrolase 1" Q13510 8 18055992-18084998 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 537.2" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 930.9;Hofbauer cells: 1315.6;Kupffer cells: 893.7;monocytes: 660.4;Neutrophils: 1696.5;Platelets: 1184.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "skin cancer: 270.7" "Adipose subcutaneous - Adipocytes (Subcutaneous), Heart muscle - Cardiomyocytes, Spleen - Macrophages, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005468 Supported "Intracellular and membrane" Enzyme NA NA 800000 "Cluster 40: Monocytes - Innate immune response" "Cluster 35: Non-specific - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 2 "HPA005468: " "potential prognostic favorable (1.66e-6)" "unprognostic (3.09e-1)" "unprognostic (7.91e-2)" "unprognostic (3.58e-1)" "unprognostic (5.64e-3)" "unprognostic (9.75e-2)" "unprognostic (5.04e-2)" "unprognostic (4.46e-2)" "unprognostic (1.40e-1)" "unprognostic (4.12e-3)" "validated prognostic favorable (9.71e-10)" "validated prognostic favorable (4.94e-5)" "unprognostic (6.01e-2)" "unprognostic (3.45e-3)" "unprognostic (1.38e-1)" "potential prognostic favorable (7.29e-4)" "unprognostic (8.94e-2)" "unprognostic (3.70e-2)" "unprognostic (7.93e-2)" "unprognostic (3.15e-1)" "potential prognostic unfavorable (6.11e-4)" "unprognostic (3.08e-1)" "unprognostic (2.67e-1)" "unprognostic (4.04e-2)" "unprognostic (2.69e-1)" "unprognostic (5.78e-2)" "unprognostic (5.35e-2)" "unprognostic (1.62e-1)" "unprognostic (1.62e-1)" "unprognostic (2.02e-1)" "unprognostic (8.39e-2)" ASAH2 ENSG00000188611 "N-acylsphingosine amidohydrolase 2" Q9NR71 10 50182778-50279720 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Lipid metabolism, Sphingolipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "intestine: 73.7" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 8.7;Early spermatids: 8.2;Enterocytes: 25.7;Epididymal clear cells: 8.2;Late spermatids: 22.0;Müller glia: 23.9;Parietal cells: 28.3" "Cell type enriched" "Detected in some" 5 "splatter: 14.0" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "cerebellum: 16.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061171 Supported Approved "Focal adhesion sites" "Intracellular and membrane" Enzyme NA NA 1100000 "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 45: Non-specific - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 109: Neurons - Neuronal signaling" "Focal adhesion sites" "HPA061171: " "unprognostic (1.51e-1)" "unprognostic (2.03e-1)" "unprognostic (2.90e-2)" "unprognostic (9.92e-2)" "unprognostic (3.23e-3)" "unprognostic (2.76e-1)" "unprognostic (4.38e-2)" "unprognostic (2.13e-1)" "unprognostic (2.49e-1)" "unprognostic (9.45e-3)" ASAH2B "ASAH2C, ASAH2L, bA449O16.3, bA98I6.3" ENSG00000204147 "N-acylsphingosine amidohydrolase 2B" P0C7U1 10 50739318-50816495 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 13.8" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 35.2;Lactotrophs: 25.7;Myonuclei: 24.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" HPA061171 Supported Approved "Focal adhesion sites" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 77: Intestine - Digestion" "Cluster 34: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "Focal adhesion sites" "HPA061171: " "unprognostic (1.11e-3)" "potential prognostic unfavorable (6.12e-4)" "unprognostic (4.11e-1)" "unprognostic (5.12e-2)" "unprognostic (5.44e-2)" "unprognostic (3.10e-1)" "unprognostic (1.08e-1)" "potential prognostic favorable (1.34e-4)" "unprognostic (7.79e-2)" "unprognostic (6.14e-2)" "potential prognostic favorable (9.32e-7)" "unprognostic (5.31e-2)" "unprognostic (1.59e-1)" "unprognostic (2.63e-2)" "unprognostic (2.20e-2)" "unprognostic (8.77e-2)" "unprognostic (7.14e-2)" "unprognostic (1.09e-1)" "unprognostic (1.60e-1)" "unprognostic (2.49e-1)" "unprognostic (4.57e-1)" "unprognostic (3.12e-1)" "unprognostic (1.18e-1)" "unprognostic (1.30e-1)" "unprognostic (2.55e-2)" "unprognostic (2.73e-2)" "unprognostic (6.98e-2)" "unprognostic (2.16e-1)" "unprognostic (1.64e-1)" "unprognostic (1.66e-1)" ASAP1 "CENTB4, DDEF1, KIAA1249, PAP, ZG14P" ENSG00000153317 "ArfGAP with SH3 domain, ankyrin repeat and PH domain 1" Q9ULH1 8 130052104-130443674 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 1451.2;Neutrophils: 2937.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 11.7" "Group enriched" "Detected in many" 5 "dendritic cells: 3.7;granulocytes: 11.7;monocytes: 6.7" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Liver - Vascular endothelial cells, Skeletal muscle - Endothelial cells, Spleen - Endothelial cells, Thyroid gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011136, CAB037292, HPA048565, CAB080440" Enhanced Approved "Golgi apparatus,Plasma membrane,Centriolar satellite" NA NA 25000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 30 "Golgi apparatus, Plasma membrane" "Centriolar satellite" "CAB037292: , CAB080440: , HPA011136: , HPA048565: " "unprognostic (9.08e-2)" "unprognostic (1.38e-2)" "unprognostic (2.48e-2)" "unprognostic (5.72e-3)" "unprognostic (5.39e-2)" "unprognostic (1.14e-1)" "unprognostic (1.96e-1)" "unprognostic (1.23e-1)" "unprognostic (5.55e-2)" "unprognostic (3.90e-3)" "potential prognostic favorable (4.71e-5)" "unprognostic (9.62e-2)" "potential prognostic unfavorable (3.50e-4)" "potential prognostic unfavorable (2.41e-6)" "unprognostic (2.08e-1)" "potential prognostic unfavorable (1.31e-5)" "unprognostic (5.62e-3)" "unprognostic (4.38e-2)" "unprognostic (1.89e-1)" "unprognostic (4.29e-3)" "unprognostic (3.10e-1)" "unprognostic (1.72e-2)" "potential prognostic unfavorable (9.20e-4)" "unprognostic (4.99e-1)" "unprognostic (2.03e-1)" "unprognostic (4.59e-2)" "unprognostic (2.49e-1)" "unprognostic (1.50e-2)" "unprognostic (2.06e-1)" "unprognostic (3.51e-2)" "unprognostic (5.08e-2)" ASAP2 "CENTB3, DDEF2, KIAA0400, PAP, SHAG1" ENSG00000151693 "ArfGAP with SH3 domain, ankyrin repeat and PH domain 2" O43150 2 9206765-9405683 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 43.7" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 463.9;Lactotrophs: 534.7;Megakaryocytes: 352.4;Platelets: 355.5;Renal connecting tubule cells: 617.6;Somatotrophs: 526.7;Thyrotrophs: 358.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "basophil: 2.7" "Lineage enriched" "Detected in single" 7 "granulocytes: 2.7" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Prostate - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018615, HPA068383" Approved Supported "Plasma membrane,Cytosol" NA NA 100000 "Cluster 41: Basophils - Unknown function" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 37: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 11 Cytosol "Plasma membrane" "CAB018615: , HPA068383: " "unprognostic (1.00e-1)" "unprognostic (7.36e-2)" "unprognostic (1.99e-1)" "unprognostic (1.94e-2)" "unprognostic (1.34e-1)" "unprognostic (5.13e-2)" "unprognostic (2.63e-1)" "unprognostic (7.39e-2)" "unprognostic (1.39e-2)" "unprognostic (1.73e-2)" "potential prognostic favorable (5.17e-7)" "unprognostic (1.01e-2)" "unprognostic (1.26e-1)" "unprognostic (2.26e-2)" "unprognostic (6.11e-2)" "unprognostic (1.22e-3)" "unprognostic (1.56e-2)" "unprognostic (1.72e-1)" "unprognostic (1.27e-1)" "unprognostic (1.24e-1)" "unprognostic (1.85e-2)" "validated prognostic unfavorable (9.24e-5)" "validated prognostic unfavorable (1.81e-5)" "unprognostic (1.39e-1)" "unprognostic (1.83e-2)" "unprognostic (2.16e-3)" "unprognostic (2.04e-1)" "unprognostic (1.28e-1)" "unprognostic (2.85e-1)" "unprognostic (6.50e-2)" "unprognostic (6.33e-2)" ASAP3 "CENTB6, DDEFL1, FLJ20199, UPLC1" ENSG00000088280 "ArfGAP with SH3 domain, ankyrin repeat and PH domain 3" Q8TDY4 1 23428563-23484568 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 62.2;Bergmann glia: 22.1;Choroid plexus epithelial cells: 60.6;Distal convoluted tubule cells: 63.4;Ependymal cells: 26.6;Loop of henle epithelial cells: 35.3;Oligodendrocyte progenitor cells: 27.5;Papillary tip epithelial cells: 34.3;Proximal tubule cells: 43.0;Renal collecting duct intercalated cells: 40.7;Renal collecting duct principal cells: 38.8;Renal connecting tubule cells: 51.1" "Cell type enhanced" "Detected in many" "astrocyte: 90.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020537, HPA020546" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 19: Astrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 28: Astrocytes - Homeostasis & neuron support" 7 Vesicles Nucleoplasm "HPA020537: , HPA020546: " "unprognostic (2.00e-2)" "unprognostic (1.14e-1)" "unprognostic (1.12e-2)" "unprognostic (4.17e-2)" "unprognostic (7.77e-2)" "unprognostic (1.14e-1)" "unprognostic (1.82e-1)" "potential prognostic favorable (4.83e-4)" "unprognostic (2.04e-2)" "unprognostic (2.72e-1)" "potential prognostic unfavorable (1.94e-4)" "unprognostic (3.29e-1)" "unprognostic (1.24e-2)" "unprognostic (2.45e-3)" "unprognostic (2.34e-1)" "unprognostic (6.52e-3)" "unprognostic (3.22e-2)" "unprognostic (1.42e-2)" "unprognostic (1.41e-1)" "unprognostic (2.57e-3)" "unprognostic (1.13e-1)" "unprognostic (2.91e-1)" "unprognostic (2.85e-1)" "unprognostic (2.78e-1)" "unprognostic (5.38e-2)" "unprognostic (2.32e-1)" "unprognostic (5.91e-2)" "unprognostic (1.20e-2)" "unprognostic (3.14e-2)" "unprognostic (2.26e-2)" "unprognostic (3.89e-2)" ASB1 ASB-1 ENSG00000065802 "Ankyrin repeat and SOCS box containing 1" Q9Y576 2 238426742-238452250 "Predicted intracellular proteins" "Ubl conjugation pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 52.8;Late primary spermatocytes: 62.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003508 Uncertain Approved Nucleoplasm NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 12 Nucleoplasm "HPA003508: " "unprognostic (1.69e-1)" "unprognostic (9.04e-3)" "unprognostic (3.33e-2)" "unprognostic (6.74e-2)" "unprognostic (1.37e-1)" "unprognostic (6.63e-2)" "unprognostic (2.83e-1)" "unprognostic (1.33e-1)" "unprognostic (1.29e-1)" "unprognostic (1.50e-1)" "unprognostic (2.82e-3)" "unprognostic (4.18e-2)" "unprognostic (1.03e-1)" "validated prognostic unfavorable (1.64e-6)" "validated prognostic unfavorable (7.04e-4)" "unprognostic (3.88e-2)" "unprognostic (1.27e-1)" "unprognostic (2.19e-2)" "unprognostic (5.47e-2)" "potential prognostic unfavorable (5.18e-4)" "unprognostic (1.91e-1)" "unprognostic (1.25e-2)" "unprognostic (1.75e-2)" "unprognostic (1.54e-1)" "unprognostic (1.16e-1)" "unprognostic (1.24e-1)" "unprognostic (6.80e-2)" "unprognostic (3.66e-1)" "unprognostic (1.76e-1)" "unprognostic (2.29e-2)" "unprognostic (7.15e-2)" ASB10 GLC1F ENSG00000146926 "Ankyrin repeat and SOCS box containing 10" Q8WXI3 7 151175698-151187832 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Disease variant, Glaucoma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 25.0;skeletal muscle: 73.0;tongue: 13.3" "Group enriched" "Detected in some" 7 "Cardiomyocytes: 92.1;Myonuclei: 131.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA079685 Enhanced NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 35: RS4;11 - Unknown function" "Cluster 55: Myocytes - Oxidative muscle function" 2 "HPA079685: " ASB11 DKFZp779E2460 ENSG00000165192 "Ankyrin repeat and SOCS box containing 11" Q8WXH4 X 15281697-15315640 "Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "heart muscle: 31.3;skeletal muscle: 107.3;tongue: 57.4" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 12.0;Cardiomyocytes: 91.8;Macrophages: 11.9;Melanocytes: 19.1;Myonuclei: 90.1;Parietal cells: 26.5;Thymic myoid cells: 12.2" "Cell type enhanced" "Detected in single" "pericyte: 1.7" "Group enriched" "Detected in some" 7 "Kidney Chromophobe (TCGA): 1.5;Skin Cutaneous Melanoma (TCGA): 3.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Stomach - Parietal cells" "Low region specificity" "Detected in many" "Not detected" "Not detected" NA NA "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 69: Skin cancer - ECM organization" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 4 "unprognostic (1.64e-2)" "unprognostic (7.42e-2)" ASB12 FLJ39577 ENSG00000198881 "Ankyrin repeat and SOCS box containing 12" Q8WXK4 X 64224194-64230607 "Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 20 "skeletal muscle: 84.8;tongue: 48.7" "Cell type enriched" "Detected in some" 5 "Late spermatids: 40.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Cardiomyocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA049542 Uncertain NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 4: Non-specific - Transcription" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" "HPA049542: " ASB13 "FLJ13134, MGC19879" ENSG00000196372 "Ankyrin repeat and SOCS box containing 13" Q8WXK3 10 5638867-5666595 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 101.0;Proximal tubule cells: 55.7;Retinal bipolar cells: 119.7;Retinal pigment epithelial cells: 174.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "dendritic cells: 13.6;monocytes: 12.9;T-cells: 4.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048293, HPA061742" Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 19 "Nucleoplasm, Golgi apparatus" "HPA048293: , HPA061742: " "unprognostic (2.02e-1)" "unprognostic (1.24e-1)" "unprognostic (1.04e-1)" "unprognostic (6.40e-3)" "unprognostic (1.48e-1)" "unprognostic (1.26e-1)" "unprognostic (1.80e-1)" "potential prognostic favorable (2.20e-5)" "unprognostic (2.48e-3)" "unprognostic (1.63e-1)" "potential prognostic favorable (9.69e-9)" "unprognostic (1.09e-2)" "unprognostic (1.29e-2)" "unprognostic (3.40e-2)" "unprognostic (4.58e-2)" "unprognostic (6.65e-2)" "unprognostic (8.02e-2)" "unprognostic (2.55e-2)" "unprognostic (2.22e-1)" "unprognostic (2.48e-1)" "unprognostic (7.29e-3)" "unprognostic (9.55e-2)" "unprognostic (4.75e-2)" "unprognostic (5.44e-1)" "potential prognostic favorable (6.49e-4)" "unprognostic (2.27e-1)" "unprognostic (9.05e-2)" "unprognostic (1.81e-2)" "unprognostic (1.30e-1)" "unprognostic (1.63e-2)" "unprognostic (1.71e-1)" ASB14 DKFZp313L0121 ENSG00000239388 "Ankyrin repeat and SOCS box containing 14" A6NK59 3 57268342-57292685 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "skeletal muscle: 26.3;tongue: 16.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 177.8;Ependymal cells: 67.3;Epicardial cells: 68.2;Myonuclei: 213.4;Respiratory ciliated cells: 116.5" "Cell type enriched" "Detected in all" 4 "ependymal cell: 71.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA029296 Approved Cytosol NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 56: Non-specific - Sensory perception" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" Cytosol "HPA029296: " "unprognostic (9.54e-3)" "unprognostic (3.15e-1)" "unprognostic (6.88e-3)" "unprognostic (2.87e-3)" ASB15 FLJ43370 ENSG00000146809 "Ankyrin repeat and SOCS box containing 15" Q8WXK1 7 123567010-123639481 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 25.5;skeletal muscle: 111.8;tongue: 78.5" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 412.8;Myonuclei: 440.0" "Cell type enhanced" "Detected in some" "ependymal cell: 2.3;upper rhombic lip: 3.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 55: Myocytes - Oxidative muscle function" 10 ASB16 FLJ30165 ENSG00000161664 "Ankyrin repeat and SOCS box containing 16" Q96NS5 17 44170447-44179084 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skeletal muscle: 63.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 25.9;Epicardial cells: 29.6;Megakaryocytes: 12.4;Myonuclei: 61.7;Retinal bipolar cells: 12.3;Retinal ganglion cells: 15.5;Retinal horizontal cells: 14.0;Thymic myoid cells: 19.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA066834 Approved Approved "Focal adhesion sites" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 25: Non-specific - Transcription" "Cluster 56: Non-specific - Sensory perception" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 1 "Focal adhesion sites" "HPA066834: " "unprognostic (4.61e-2)" "unprognostic (1.14e-1)" "unprognostic (8.76e-2)" "unprognostic (1.25e-1)" "unprognostic (3.18e-3)" "unprognostic (6.46e-2)" "unprognostic (5.96e-2)" "unprognostic (3.21e-3)" "unprognostic (1.50e-1)" "potential prognostic unfavorable (2.61e-4)" "unprognostic (2.27e-1)" "unprognostic (1.93e-1)" "unprognostic (6.04e-2)" "unprognostic (1.45e-1)" "unprognostic (7.45e-3)" "unprognostic (3.14e-1)" "unprognostic (2.76e-1)" "unprognostic (3.34e-3)" "unprognostic (7.04e-2)" "unprognostic (1.71e-3)" "unprognostic (8.32e-2)" "unprognostic (1.68e-3)" "unprognostic (1.54e-3)" "unprognostic (4.15e-2)" "unprognostic (4.49e-2)" "unprognostic (2.48e-2)" "unprognostic (5.97e-2)" "unprognostic (5.30e-3)" ASB17 ENSG00000154007 "Ankyrin repeat and SOCS box containing 17" Q8WXJ9 1 75918873-75932404 "Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 214 "testis: 46.6" "Group enriched" "Detected in some" 26 "Early spermatids: 1284.5;Late primary spermatocytes: 345.0;Late spermatids: 472.9" "Low cell type specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" ASB18 ENSG00000182177 "Ankyrin repeat and SOCS box containing 18" Q6ZVZ8 2 236193459-236264409 "Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 6 "heart muscle: 6.6;skeletal muscle: 11.0" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 93.1;Myonuclei: 277.0" "Cell type enhanced" "Detected in many" "Bergmann glia: 81.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA068447 Approved Nucleoli,Mitochondria NA NA "Cluster 41: Striated muscle - Muscle contraction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 55: Myocytes - Oxidative muscle function" Mitochondria Nucleoli "HPA068447: " ASB2 ASB-2 ENSG00000100628 "Ankyrin repeat and SOCS box containing 2" Q96Q27 14 93934166-93976739 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 494.8;tongue: 147.3" "Cell type enhanced" "Detected in some" "B-cells: 1.1;Brain excitatory neurons: 1.6;Cardiomyocytes: 11.3;Epicardial cells: 2.3;Microglia: 2.4;Myonuclei: 3.0;Smooth muscle cells: 1.6;Vascular smooth muscle cells: 3.4" "Group enriched" "Detected in some" 4 "upper-layer intratelencephalic: 11.4;vascular associated smooth muscle cell: 21.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 7 "eosinophil: 51.0" "Lineage enriched" "Detected in many" 7 "granulocytes: 51.0" "Group enriched" "Detected in some" 7 "lymphoma: 26.2;Myeloma: 13.8" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Adrenal gland - Smooth muscle cells, Heart muscle - Cardiomyocytes, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Skin - Smooth muscle cells, Stomach - Fibroblasts, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA001546 Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 53: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 7 "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "HPA001546: " "unprognostic (3.26e-2)" "unprognostic (3.59e-2)" "unprognostic (1.74e-3)" "unprognostic (1.32e-1)" "unprognostic (2.65e-1)" "unprognostic (5.88e-3)" "unprognostic (5.92e-2)" "unprognostic (1.88e-1)" "unprognostic (2.62e-1)" "unprognostic (9.53e-3)" "unprognostic (1.44e-3)" "unprognostic (2.55e-1)" "unprognostic (1.76e-1)" "unprognostic (4.40e-2)" "unprognostic (7.05e-2)" "unprognostic (3.59e-2)" "unprognostic (3.83e-1)" "unprognostic (2.18e-1)" "unprognostic (3.78e-2)" "unprognostic (1.48e-1)" "unprognostic (1.66e-1)" ASB3 ASB-3 ENSG00000115239 "Ankyrin repeat and SOCS box containing 3" Q9Y575 2 53532672-53860160 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 874.7;Oligodendrocyte progenitor cells: 497.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003940 Uncertain NA NA "Cluster 32: Basophils - Transcription" "Cluster 78: Brain - Neuronal signaling" "Cluster 9: Non-specific - Receptor signaling" "Cluster 59: Leukemia - T-cell receptor" "Cluster 28: Astrocytes - Homeostasis & neuron support" 10 "HPA003940: " "unprognostic (1.98e-1)" "unprognostic (1.00e-1)" "unprognostic (8.17e-2)" "unprognostic (2.13e-2)" "unprognostic (9.83e-2)" "unprognostic (1.39e-1)" "unprognostic (3.23e-2)" "potential prognostic favorable (8.95e-4)" "unprognostic (2.44e-1)" "potential prognostic unfavorable (7.80e-4)" "unprognostic (1.22e-1)" "unprognostic (1.35e-1)" "unprognostic (1.22e-1)" "unprognostic (1.21e-3)" "unprognostic (2.67e-2)" "unprognostic (6.16e-2)" "unprognostic (7.59e-3)" "unprognostic (4.54e-3)" "unprognostic (6.13e-2)" "unprognostic (8.01e-2)" "unprognostic (1.79e-1)" "unprognostic (4.14e-2)" "unprognostic (2.75e-3)" "unprognostic (6.35e-2)" "unprognostic (5.84e-2)" "unprognostic (1.23e-2)" "unprognostic (4.57e-2)" "unprognostic (2.77e-1)" "unprognostic (7.82e-3)" "unprognostic (3.67e-2)" "unprognostic (2.68e-1)" ASB4 ASB-4 ENSG00000005981 "Ankyrin repeat and SOCS box containing 4" Q9Y574 7 95478444-95540233 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 44.5;skeletal muscle: 32.0" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 190.5;Adrenal medulla cells: 42.5;Early spermatids: 37.3;Lactotrophs: 122.1;Late primary spermatocytes: 26.2;Late spermatids: 59.0;Myonuclei: 35.0;Somatotrophs: 50.9" "Cell type enhanced" "Detected in some" "astrocyte: 7.6" "Cancer enhanced" "Detected in some" "Stomach Adenocarcinoma (TCGA): 3.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 7.9;skin cancer: 9.4" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Pituitary gland - Lactotropes, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Testis - Late spermatids" "Group enriched" "Detected in many" 4 "basal ganglia: 9.5;hypothalamus: 31.7" "Region enriched" "Detected in single" 11 "midbrain: 6.6" HPA055240 Uncertain NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 18: Adrenal cortex cells - Steroidogensis" 7 "HPA055240: " "unprognostic (1.49e-2)" "unprognostic (5.35e-2)" "unprognostic (6.63e-2)" "unprognostic (4.79e-1)" "unprognostic (1.11e-1)" ASB5 ENSG00000164122 "Ankyrin repeat and SOCS box containing 5" Q8WWX0 4 176213673-176277571 "Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "skeletal muscle: 203.4;tongue: 62.7" "Cell type enhanced" "Detected in some" "Late spermatids: 527.3;Myonuclei: 1830.2;Myosatellite cells: 133.2;Smooth muscle cells: 106.9;Thymic myoid cells: 376.6" "Cell type enriched" "Detected in many" 5 "oligodendrocyte precursor cell: 17.4" "Cancer enhanced" "Detected in some" "Kidney Chromophobe (TCGA): 8.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Bile duct cancer: 16.0;Sarcoma: 23.3" "Heart muscle - Cardiomyocytes, Pituitary gland - Gonadotropes, Prostate - Smooth muscle cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA028870 Approved "Plasma membrane" NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 30: White matter - Myelination" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 55: Myocytes - Oxidative muscle function" "Plasma membrane" "HPA028870: " "unprognostic (2.42e-1)" "unprognostic (2.38e-1)" "potential prognostic unfavorable (1.16e-4)" "unprognostic (8.66e-2)" "unprognostic (2.88e-2)" "unprognostic (1.02e-1)" "unprognostic (2.99e-2)" ASB6 ENSG00000148331 "Ankyrin repeat and SOCS box containing 6" Q9NWX5 9 129634604-129642169 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 59.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004341 Approved NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 26: Keratinocytes - Keratinization" 63 "HPA004341: " "unprognostic (1.18e-1)" "unprognostic (1.47e-2)" "unprognostic (1.63e-1)" "unprognostic (2.48e-1)" "unprognostic (2.25e-3)" "unprognostic (6.82e-3)" "unprognostic (4.00e-1)" "unprognostic (4.47e-2)" "unprognostic (1.34e-1)" "unprognostic (1.83e-1)" "unprognostic (1.92e-2)" "unprognostic (3.91e-2)" "unprognostic (1.86e-1)" "potential prognostic unfavorable (3.96e-5)" "unprognostic (1.55e-2)" "unprognostic (2.53e-1)" "unprognostic (3.94e-2)" "unprognostic (5.36e-2)" "unprognostic (3.54e-3)" "unprognostic (9.08e-2)" "unprognostic (5.71e-2)" "unprognostic (1.67e-1)" "unprognostic (1.68e-1)" "unprognostic (3.38e-2)" "unprognostic (1.98e-1)" "unprognostic (1.96e-1)" "unprognostic (1.34e-1)" "unprognostic (2.38e-2)" "unprognostic (3.61e-1)" "unprognostic (1.43e-1)" "unprognostic (1.65e-2)" ASB7 ENSG00000183475 "Ankyrin repeat and SOCS box containing 7" Q9H672 15 100602589-100651701 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003300 Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 22 "Golgi apparatus, Vesicles" Nucleoplasm "HPA003300: " "unprognostic (6.45e-2)" "unprognostic (2.21e-1)" "unprognostic (1.01e-1)" "unprognostic (1.01e-1)" "unprognostic (4.35e-2)" "unprognostic (4.97e-2)" "unprognostic (2.43e-1)" "unprognostic (2.42e-1)" "unprognostic (1.88e-1)" "unprognostic (1.25e-2)" "validated prognostic favorable (9.05e-8)" "validated prognostic favorable (5.07e-4)" "unprognostic (3.30e-1)" "unprognostic (1.13e-1)" "unprognostic (8.03e-2)" "unprognostic (1.31e-1)" "unprognostic (1.95e-2)" "unprognostic (1.06e-1)" "unprognostic (1.12e-1)" "unprognostic (6.65e-2)" "unprognostic (1.03e-1)" "unprognostic (7.73e-2)" "unprognostic (1.13e-2)" "unprognostic (1.39e-1)" "unprognostic (5.07e-2)" "unprognostic (2.14e-1)" "unprognostic (1.16e-1)" "unprognostic (1.10e-1)" "unprognostic (5.39e-2)" "unprognostic (1.66e-1)" "unprognostic (1.04e-1)" ASB8 "FLJ21255, MGC5540" ENSG00000177981 "Ankyrin repeat and SOCS box containing 8" Q9H765 12 48147789-48181213 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 273.6;tongue: 172.5" "Cell type enhanced" "Detected in all" "Late spermatids: 133.9;Myonuclei: 144.3;Platelets: 201.7;Thymic myoid cells: 460.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Minor Salivary Gland - Endothelial cells" "Low region specificity" "Detected in all" HPA003299 Approved NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 15: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 17 "HPA003299: " "unprognostic (7.43e-2)" "unprognostic (8.08e-3)" "unprognostic (1.86e-2)" "unprognostic (1.32e-1)" "unprognostic (2.90e-1)" "unprognostic (2.53e-2)" "unprognostic (2.07e-2)" "unprognostic (9.96e-2)" "unprognostic (1.03e-1)" "unprognostic (3.44e-2)" "potential prognostic favorable (6.13e-6)" "unprognostic (8.23e-3)" "unprognostic (1.68e-1)" "unprognostic (1.14e-3)" "unprognostic (3.56e-1)" "unprognostic (1.03e-1)" "unprognostic (4.08e-2)" "unprognostic (2.39e-1)" "unprognostic (2.18e-1)" "unprognostic (7.50e-2)" "unprognostic (1.06e-2)" "unprognostic (4.05e-2)" "unprognostic (1.41e-1)" "unprognostic (5.12e-1)" "unprognostic (2.86e-1)" "unprognostic (8.12e-3)" "unprognostic (5.67e-2)" "unprognostic (5.46e-2)" "unprognostic (4.10e-2)" "unprognostic (1.53e-1)" "unprognostic (1.87e-1)" ASB9 "DKFZP564L0862, FLJ20636, MGC4954" ENSG00000102048 "Ankyrin repeat and SOCS box containing 9" Q96DX5 X 15235288-15270467 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 15.7;liver: 16.3;testis: 24.2" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 139.9;Melanocytes: 22.6;Parietal cells: 30.1;Renal collecting duct intercalated cells: 28.5;Sertoli cells: 41.3;Undifferentiated spermatogonia: 160.7" "Cell type enhanced" "Detected in some" "endothelial cell: 8.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 1.6" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "skin cancer: 19.9" "Liver - Hepatocytes, Pancreas - Beta cells, Thyroid gland - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA003014, HPA003060, CAB004997" Enhanced NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 57: Testis - Spermatogenesis" "Cluster 6: Non-specific - Immune response" "Cluster 69: Skin cancer - ECM organization" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 43 "CAB004997: , HPA003014: , HPA003060: " "unprognostic (2.24e-2)" "unprognostic (2.82e-3)" "unprognostic (2.64e-2)" "unprognostic (1.14e-1)" "unprognostic (1.48e-1)" "unprognostic (6.21e-2)" "unprognostic (1.95e-1)" "unprognostic (4.49e-2)" "unprognostic (1.37e-2)" "unprognostic (3.49e-1)" "unprognostic (1.18e-3)" "unprognostic (1.07e-2)" "unprognostic (2.84e-3)" "unprognostic (1.08e-1)" "unprognostic (1.14e-1)" "unprognostic (1.55e-1)" "unprognostic (1.40e-1)" "unprognostic (4.65e-2)" "unprognostic (9.84e-2)" "unprognostic (6.07e-2)" "unprognostic (5.85e-1)" "unprognostic (1.85e-1)" "unprognostic (7.80e-3)" "unprognostic (6.10e-3)" "unprognostic (1.50e-2)" "unprognostic (4.27e-2)" "unprognostic (5.95e-2)" "unprognostic (1.28e-2)" "unprognostic (1.23e-1)" "unprognostic (8.47e-2)" "unprognostic (1.76e-1)" ASCC1 "ASC1p50, CGI-18, Em:AC022392.3, p50" ENSG00000138303 "Activating signal cointegrator 1 complex subunit 1" Q8N9N2 10 72096032-72217134 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" Neurodegeneration "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Cardiomyocytes: 656.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038038, HPA057567" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 32: Basophils - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 16 Nucleoplasm Cytosol "HPA038038: , HPA057567: " "unprognostic (1.04e-1)" "unprognostic (6.13e-2)" "unprognostic (2.03e-1)" "potential prognostic unfavorable (1.49e-5)" "unprognostic (6.92e-2)" "unprognostic (3.70e-2)" "unprognostic (7.47e-2)" "potential prognostic favorable (2.73e-5)" "unprognostic (1.34e-2)" "unprognostic (5.93e-2)" "potential prognostic favorable (1.48e-6)" "unprognostic (2.82e-2)" "unprognostic (5.72e-2)" "unprognostic (1.69e-3)" "unprognostic (3.21e-2)" "unprognostic (2.16e-3)" "unprognostic (6.64e-2)" "unprognostic (2.01e-2)" "unprognostic (8.13e-2)" "unprognostic (2.25e-2)" "unprognostic (3.66e-2)" "potential prognostic unfavorable (5.19e-4)" "unprognostic (1.42e-2)" "unprognostic (2.06e-1)" "unprognostic (1.63e-1)" "unprognostic (3.74e-2)" "unprognostic (8.90e-2)" "unprognostic (3.21e-1)" "unprognostic (2.48e-1)" "unprognostic (2.86e-2)" "unprognostic (6.83e-2)" ASCC2 "ASC1p100, DKFZp586O0223, FLJ21588" ENSG00000100325 "Activating signal cointegrator 1 complex subunit 2" Q9H1I8 22 29788609-29838304 "Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 659.7;Late spermatids: 200.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001439, HPA052879" Approved Approved "Nucleoplasm,Focal adhesion sites,Cytosol" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 66: Non-specific - Mitochondria" "Cluster 84: Apical squamous epithelium - Cornification" 26 "Focal adhesion sites, Cytosol" Nucleoplasm "HPA001439: , HPA052879: " "unprognostic (1.95e-1)" "unprognostic (2.55e-2)" "unprognostic (2.16e-1)" "unprognostic (3.78e-2)" "unprognostic (1.33e-1)" "unprognostic (1.21e-1)" "unprognostic (7.40e-2)" "unprognostic (1.22e-1)" "unprognostic (7.79e-2)" "unprognostic (1.52e-2)" "unprognostic (2.43e-3)" "unprognostic (3.97e-2)" "unprognostic (2.02e-2)" "unprognostic (8.36e-2)" "unprognostic (2.52e-2)" "unprognostic (6.86e-2)" "unprognostic (4.12e-2)" "unprognostic (2.63e-1)" "unprognostic (6.12e-3)" "unprognostic (3.69e-1)" "unprognostic (1.29e-1)" "unprognostic (4.73e-2)" "unprognostic (3.92e-2)" "unprognostic (2.62e-1)" "unprognostic (4.11e-2)" "unprognostic (2.06e-2)" "unprognostic (1.80e-1)" "unprognostic (1.04e-1)" "unprognostic (1.52e-1)" "unprognostic (1.07e-1)" "unprognostic (1.55e-1)" ASCC3 "ASC1p200, dJ121G13.4, dJ467N11.1, HELIC1, RNAH" ENSG00000112249 "Activating signal cointegrator 1 complex subunit 3" Q8N3C0 6 100508194-100881372 "Enzymes, Essential proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Helicase, Hydrolase, Isomerase" "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031608, HPA031609, HPA031610" Enhanced Supported "Golgi apparatus,Cytosol" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 76: Non-specific - Metabolism" "Cluster 55: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" 52 Cytosol "Golgi apparatus" "HPA031608: , HPA031609: , HPA031610: " "unprognostic (1.17e-2)" "unprognostic (1.69e-2)" "unprognostic (1.65e-2)" "unprognostic (1.52e-2)" "unprognostic (4.29e-3)" "unprognostic (1.28e-1)" "unprognostic (9.27e-3)" "unprognostic (1.42e-1)" "unprognostic (1.57e-1)" "unprognostic (1.51e-2)" "potential prognostic favorable (5.33e-6)" "unprognostic (1.59e-2)" "unprognostic (6.73e-2)" "unprognostic (1.09e-1)" "unprognostic (2.36e-1)" "unprognostic (4.62e-2)" "potential prognostic unfavorable (2.18e-4)" "unprognostic (2.92e-1)" "unprognostic (3.17e-1)" "unprognostic (1.44e-1)" "unprognostic (1.03e-1)" "unprognostic (4.72e-3)" "unprognostic (2.11e-3)" "unprognostic (4.05e-1)" "unprognostic (2.60e-2)" "unprognostic (3.28e-3)" "unprognostic (4.18e-1)" "unprognostic (1.37e-1)" "unprognostic (2.00e-1)" "unprognostic (2.23e-1)" "unprognostic (1.09e-1)" ASCL1 "ASH1, bHLHa46, HASH1" ENSG00000139352 "Achaete-scute family bHLH transcription factor 1" P50553 12 102957674-102960513 "Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 15.5;liver: 10.4;pituitary gland: 28.2" "Cell type enhanced" "Detected in some" "Bergmann glia: 23.0;Corticotrophs: 260.2;Medullary thymic epithelial cells: 64.8;Neuroendocrine cells: 47.7;Oligodendrocyte progenitor cells: 86.0;Pancreatic islet cells: 24.8" "Cell type enhanced" "Detected in many" "Bergmann glia: 32.8;oligodendrocyte precursor cell: 113.2" "Group enriched" "Detected in many" 4 "Glioblastoma Multiforme (TCGA): 35.7;Lung Adenocarcinoma (TCGA): 22.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "lung cancer: 99.1;Neuroblastoma: 67.5;prostate cancer: 57.5" "Minor Salivary Gland - Plasma cells, Pituitary gland - Corticotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029217, HPA076307" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 12 Nucleoplasm Cytosol "HPA029217: , HPA076307: " "unprognostic (2.17e-2)" "unprognostic (8.07e-2)" "unprognostic (5.18e-1)" "unprognostic (8.23e-2)" "unprognostic (6.07e-3)" "unprognostic (1.90e-2)" "unprognostic (3.51e-2)" "unprognostic (7.43e-2)" "unprognostic (1.11e-2)" "unprognostic (3.28e-1)" "unprognostic (2.89e-1)" "unprognostic (1.06e-2)" "unprognostic (1.82e-1)" "unprognostic (3.74e-2)" ASCL2 "ASH2, bHLHa45, HASH2" ENSG00000183734 "Achaete-scute family bHLH transcription factor 2" Q99929 11 2268498-2270588 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 6.5;salivary gland: 7.6;skin 1: 8.0" "Cell type enriched" "Detected in many" 6 "Extravillous trophoblasts: 1529.3" "Group enriched" "Detected in some" 5 "central nervous system macrophage: 6.9;leukocyte: 9.8" "Group enriched" "Detected in many" 5 "Colon Adenocarcinoma (TCGA): 81.2;Rectum Adenocarcinoma (TCGA): 96.8;Stomach Adenocarcinoma (TCGA): 38.8" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 7.9" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 4 "colorectal cancer: 59.2;Gastric cancer: 17.0" "Breast - Breast glandular cells, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 27: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 2 "unprognostic (8.15e-2)" "unprognostic (9.51e-3)" "unprognostic (1.69e-1)" "unprognostic (4.25e-3)" "unprognostic (2.60e-1)" "unprognostic (1.79e-3)" "unprognostic (3.21e-1)" "unprognostic (1.10e-2)" "unprognostic (4.22e-3)" "unprognostic (3.41e-2)" "unprognostic (3.10e-2)" "unprognostic (5.23e-2)" "unprognostic (1.43e-2)" "unprognostic (1.40e-2)" "unprognostic (1.04e-1)" "potential prognostic favorable (5.00e-4)" "unprognostic (1.29e-1)" "unprognostic (3.32e-1)" "unprognostic (7.85e-2)" "unprognostic (2.73e-2)" "unprognostic (5.35e-3)" "unprognostic (8.88e-2)" "unprognostic (2.01e-2)" ASCL3 "bHLHa42, HASH3, Sgn1" ENSG00000176009 "Achaete-scute family bHLH transcription factor 3" Q9NQ33 11 8937578-8943016 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 19 "salivary gland: 9.5" "Group enriched" "Detected in some" 33 "Respiratory ionocytes: 817.9;Salivary ionocytes: 1560.8" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Bladder Urothelial Carcinoma (TCGA): 1.6;Kidney Chromophobe (TCGA): 2.7" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Minor Salivary Gland - Minor salivary gland ductal cells" "Not detected" "Not detected" HPA027032 Uncertain NA NA "Cluster 82: Salivary gland - Secretion" "Cluster 25: Non-specific - Transcription" "Cluster 6: Leukemia - Signal transduction" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 6 "HPA027032: " "unprognostic (3.93e-1)" ASCL4 "bHLHa44, HASH4" ENSG00000187855 "Achaete-scute family bHLH transcription factor 4" Q6XD76 12 107774704-107776644 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "cDC: 2.2;Epicardial cells: 2.3;Microglia: 9.9;Respiratory ionocytes: 5.1;Retinal ganglion cells: 3.9" "Cell type enriched" "Detected in single" 31 "central nervous system macrophage: 11.8" "Cancer enhanced" "Detected in single" "Kidney Chromophobe (TCGA): 2.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Inner root sheath cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA036116 Uncertain NA NA "Cluster 59: Leukemia - T-cell receptor" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 42 "HPA036116: " "unprognostic (4.30e-2)" "unprognostic (1.64e-2)" "unprognostic (1.51e-3)" ASCL5 "AmeloD, ASH-5, bHLHa47" ENSG00000232237 "Achaete-scute family bHLH transcription factor 5" 1 201113943-201127184 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "pancreas: 1.8" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 2.1;Enteric stem cells: 1.5;Myonuclei: 1.1;Oligodendrocyte progenitor cells: 1.2;Other brain neurons: 1.3;Pancreatic acinar cells: 1.7;Thymic myoid cells: 6.8" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 2.7;Rhabdoid: 2.2" "Group enriched" "Detected in some" 5 "amygdala: 2.8;cerebral cortex: 2.1;hippocampal formation: 1.6" "Not detected" "Not detected" NA NA "Cluster 70: Non-specific - Protein processing" "Cluster 14: Neurons - Synaptic function" "Cluster 70: DU4475 - Unknown function" "Cluster 46: Skeletal myocytes - Muscle structure & formation" "unprognostic (6.45e-3)" "unprognostic (1.93e-1)" "unprognostic (1.89e-2)" "unprognostic (5.08e-2)" "unprognostic (2.97e-1)" "unprognostic (1.23e-1)" ASDURF ENSG00000286053 "ASNSD1 upstream open reading frame" L0R819 2 189661452-189666437 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 58: Non-specific - Nuclear processes" 13 "unprognostic (3.16e-1)" "unprognostic (3.76e-2)" "unprognostic (5.26e-2)" "unprognostic (2.35e-1)" "unprognostic (1.51e-1)" "unprognostic (4.32e-2)" "unprognostic (2.03e-1)" "potential prognostic unfavorable (7.35e-6)" "unprognostic (4.21e-2)" "unprognostic (1.50e-2)" "unprognostic (1.97e-2)" "unprognostic (1.80e-2)" "unprognostic (3.86e-2)" "unprognostic (2.99e-1)" "unprognostic (9.50e-2)" "unprognostic (1.45e-1)" "unprognostic (1.64e-1)" "unprognostic (7.42e-2)" "unprognostic (2.10e-1)" "unprognostic (4.55e-2)" "unprognostic (1.46e-1)" "unprognostic (3.43e-1)" ASF1A "CIA, DKFZP547E2110" ENSG00000111875 "Anti-silencing function 1A histone chaperone" Q9Y294 6 118894152-118909171 "Predicted intracellular proteins" "DNA damage, Transcription, Transcription regulation" "Chaperone, Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Megakaryocytes: 92.7;Oocytes: 345.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030502, HPA071495" Enhanced Nucleoplasm No No "Cluster 39: T-cells - T-cell receptor" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 55: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 9: T-cells - Adaptive immunity: Regulation" 130 Nucleoplasm "HPA030502: , HPA071495: " "unprognostic (9.51e-3)" "unprognostic (1.67e-2)" "unprognostic (2.87e-2)" "unprognostic (1.27e-1)" "unprognostic (3.36e-1)" "unprognostic (2.46e-3)" "unprognostic (2.74e-3)" "unprognostic (1.24e-2)" "unprognostic (2.42e-1)" "potential prognostic unfavorable (1.99e-4)" "potential prognostic favorable (2.22e-5)" "unprognostic (1.02e-2)" "unprognostic (2.61e-3)" "potential prognostic unfavorable (8.64e-8)" "unprognostic (3.86e-1)" "unprognostic (1.89e-1)" "unprognostic (3.23e-2)" "unprognostic (1.04e-1)" "unprognostic (1.41e-2)" "unprognostic (1.32e-1)" "unprognostic (1.93e-2)" "unprognostic (1.69e-1)" "unprognostic (3.29e-1)" "unprognostic (2.35e-1)" "unprognostic (1.30e-2)" "unprognostic (1.58e-1)" "unprognostic (1.28e-1)" "unprognostic (2.10e-2)" "unprognostic (2.08e-1)" "unprognostic (2.23e-2)" "unprognostic (3.81e-1)" ASF1B FLJ10604 ENSG00000105011 "Anti-silencing function 1B histone chaperone" Q9NVP2 19 14119512-14136613 "Predicted intracellular proteins" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Chaperone, Chromatin regulator, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 21.6;testis: 36.2" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 1.5;Early primary spermatocytes: 1.4;Early spermatids: 7.0;Late primary spermatocytes: 1.8;Late spermatids: 2.9;Loop of henle epithelial cells: 1.3;Microglia: 1.6;Papillary tip epithelial cells: 2.0;Platelets: 1.4;Renal collecting duct intercalated cells: 1.3;Renal collecting duct principal cells: 2.6;Thymic myoid cells: 1.4" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 1.9;leukocyte: 2.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 7 "neutrophil: 60.3" "Lineage enriched" "Detected in all" 7 "granulocytes: 60.3" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Kidney - Macrophages, Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA054036, HPA069385" Enhanced Enhanced Nucleoplasm NA Yes "Cluster 28: Neutrophils - Unknown function" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 6: Non-specific - Immune response" "Cluster 23: Non-specific - Transcription" "Cluster 102: Non-specific - Mixed function" 118 Nucleoplasm "HPA054036: , HPA069385: " "unprognostic (2.67e-1)" "unprognostic (4.00e-2)" "unprognostic (2.06e-1)" "potential prognostic favorable (8.46e-4)" "unprognostic (1.06e-1)" "unprognostic (2.69e-1)" "unprognostic (4.01e-2)" "unprognostic (8.70e-2)" "unprognostic (6.04e-2)" "potential prognostic unfavorable (1.21e-6)" "validated prognostic unfavorable (1.59e-4)" "validated prognostic unfavorable (1.59e-6)" "potential prognostic unfavorable (3.25e-10)" "validated prognostic unfavorable (3.84e-4)" "validated prognostic unfavorable (3.06e-9)" "validated prognostic unfavorable (2.45e-4)" "validated prognostic unfavorable (3.22e-5)" "potential prognostic favorable (7.57e-4)" "unprognostic (5.45e-3)" "unprognostic (1.25e-1)" "unprognostic (2.96e-1)" "potential prognostic unfavorable (3.01e-6)" "unprognostic (1.83e-1)" "unprognostic (1.78e-2)" "unprognostic (6.20e-2)" "unprognostic (8.69e-2)" "unprognostic (2.80e-3)" "potential prognostic favorable (4.21e-4)" "unprognostic (1.38e-1)" "unprognostic (1.89e-2)" "unprognostic (6.48e-2)" ASGR1 CLEC4H1 ENSG00000141505 "Asialoglycoprotein receptor 1" P07306 17 7173431-7179564 "Predicted intracellular proteins, Predicted secreted proteins" "Endocytosis, Host-virus interaction" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 45 "liver: 1142.4" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 1286.5" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 37.7" "Cancer enriched" "Detected in all" 59 "Liver Hepatocellular Carcinoma (TCGA): 494.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 115.4;intermediate monocyte: 55.6;myeloid DC: 41.2" "Group enriched" "Detected in many" 8 "dendritic cells: 41.2;monocytes: 115.4" "Cancer enriched" "Detected in many" 11 "liver cancer: 80.4" "Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in all" 9 "cerebellum: 44.1" "Not detected" "Not detected" "HPA011954, HPA012852" Enhanced Supported "Vesicles,Cell Junctions" "Secreted to blood" Receptor NA NA 1710000 360000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 2: Neurons - Nucleosome" "Cluster 18: Liver cancer - Metabolism" "Cluster 93: Hepatocytes - Bile production & excretion" 31 Vesicles "Cell Junctions" "HPA011954: , HPA012852: " "unprognostic (7.90e-2)" "unprognostic (1.48e-3)" "unprognostic (2.37e-1)" "unprognostic (1.68e-1)" "unprognostic (1.47e-1)" "unprognostic (3.96e-2)" "unprognostic (7.16e-2)" "unprognostic (1.13e-3)" "unprognostic (2.67e-2)" "unprognostic (1.52e-2)" "potential prognostic unfavorable (1.08e-10)" "unprognostic (5.24e-2)" "unprognostic (2.27e-2)" "unprognostic (5.73e-3)" "potential prognostic favorable (2.86e-4)" "unprognostic (1.35e-2)" "unprognostic (8.29e-2)" "unprognostic (6.92e-2)" "unprognostic (1.23e-2)" "unprognostic (2.11e-1)" "unprognostic (1.31e-1)" "unprognostic (3.25e-3)" "unprognostic (1.53e-2)" "unprognostic (1.38e-1)" "unprognostic (1.74e-1)" "unprognostic (7.43e-2)" "unprognostic (8.28e-3)" "unprognostic (2.93e-1)" "unprognostic (8.05e-2)" "potential prognostic unfavorable (8.17e-4)" "unprognostic (4.86e-2)" ASGR2 CLEC4H2 ENSG00000161944 "Asialoglycoprotein receptor 2" P07307 17 7101322-7115700 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Endocytosis, Host-virus interaction" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 34 "liver: 559.0" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 951.2" "Cell type enriched" "Detected in some" 4 "hippocampal CA1-3: 10.3" "Cancer enriched" "Detected in many" 37 "Liver Hepatocellular Carcinoma (TCGA): 500.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 8 "classical monocyte: 110.6;myeloid DC: 64.9" "Group enriched" "Detected in many" 52 "dendritic cells: 64.9;monocytes: 110.6" "Cancer enriched" "Detected in some" 12 "liver cancer: 99.3" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Liver - Hepatocytes, Lung - Neutrophils_2, Skin - Keratinocyte (granular), Spleen - Neutrophils_2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA014899, HPA015998" Enhanced Supported "Endoplasmic reticulum,Plasma membrane" NA NA 23000000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 53: Liver - Plasma proteins" "Cluster 12: Non-specific - Vasculature" "Cluster 18: Liver cancer - Metabolism" "Cluster 93: Hepatocytes - Bile production & excretion" 8 "Endoplasmic reticulum, Plasma membrane" "HPA014899: , HPA015998: " "potential prognostic favorable (1.27e-4)" "unprognostic (1.53e-2)" "unprognostic (1.10e-1)" "unprognostic (9.40e-3)" "unprognostic (1.33e-1)" "potential prognostic favorable (6.90e-4)" "unprognostic (1.27e-3)" "unprognostic (1.03e-1)" "unprognostic (5.05e-2)" "unprognostic (7.20e-2)" "unprognostic (1.63e-3)" "unprognostic (4.88e-2)" ASH1L "ASH1, ASH1L1, huASH1, KMT2H" ENSG00000116539 "ASH1 like histone lysine methyltransferase" Q9NR48 1 155335268-155563162 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Methyltransferase, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004806 Approved Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 24: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" 8 "Nucleoplasm, Golgi apparatus" "Nuclear bodies" "HPA004806: " "unprognostic (1.15e-2)" "unprognostic (8.45e-2)" "unprognostic (3.41e-1)" "unprognostic (3.54e-3)" "unprognostic (6.52e-2)" "unprognostic (3.86e-2)" "unprognostic (3.99e-2)" "unprognostic (5.19e-2)" "unprognostic (3.25e-2)" "unprognostic (4.66e-2)" "validated prognostic favorable (2.61e-5)" "validated prognostic favorable (4.15e-4)" "unprognostic (3.31e-1)" "unprognostic (4.96e-2)" "unprognostic (3.11e-1)" "unprognostic (2.42e-1)" "unprognostic (7.87e-2)" "unprognostic (3.07e-2)" "unprognostic (5.85e-2)" "unprognostic (1.48e-1)" "unprognostic (1.22e-2)" "unprognostic (7.50e-2)" "unprognostic (1.37e-1)" "unprognostic (7.28e-2)" "unprognostic (1.18e-1)" "unprognostic (3.75e-1)" "unprognostic (1.88e-1)" "unprognostic (2.65e-1)" "unprognostic (2.92e-1)" "unprognostic (6.99e-2)" "unprognostic (1.50e-1)" ASH2L "ASH2, ASH2L1, ASH2L2, Bre2" ENSG00000129691 "ASH2 like, histone lysine methyltransferase complex subunit" Q9UBL3 8 38105493-38144076 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Sertoli cells: 143.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042289 Approved Supported "Nucleoplasm,Plasma membrane" Yes No "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 61: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 40: Non-specific - Unknown function" "Cluster 94: Gonadal somatic cells - Mixed function" 84 Nucleoplasm "Plasma membrane" "HPA042289: " "unprognostic (1.27e-3)" "unprognostic (4.22e-3)" "potential prognostic unfavorable (2.09e-4)" "unprognostic (3.78e-2)" "unprognostic (1.62e-3)" "unprognostic (8.52e-2)" "unprognostic (2.75e-1)" "unprognostic (1.27e-3)" "unprognostic (7.33e-2)" "unprognostic (2.62e-3)" "potential prognostic favorable (1.81e-6)" "unprognostic (3.74e-3)" "unprognostic (1.29e-1)" "unprognostic (6.55e-2)" "unprognostic (1.72e-1)" "unprognostic (6.16e-2)" "unprognostic (1.37e-1)" "unprognostic (2.17e-3)" "unprognostic (1.78e-1)" "unprognostic (5.65e-2)" "unprognostic (2.37e-2)" "unprognostic (8.61e-2)" "unprognostic (2.70e-1)" "unprognostic (3.22e-2)" "unprognostic (1.47e-1)" "unprognostic (9.42e-2)" "unprognostic (4.76e-2)" "unprognostic (1.96e-1)" "unprognostic (4.17e-2)" "unprognostic (1.61e-1)" "unprognostic (1.97e-1)" ASIC1 "ACCN2, BNaC2, hBNaC2" ENSG00000110881 "Acid sensing ion channel subunit 1" P78348 12 50057548-50083611 "Predicted membrane proteins" "Calcium transport, Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 30.0" "Cell type enhanced" "Detected in some" "Astrocytes: 43.4;Brain excitatory neurons: 11.9;Brain inhibitory neurons: 32.6;Choroid plexus epithelial cells: 21.7;Oligodendrocyte progenitor cells: 106.3;Oligodendrocytes: 30.2;Other brain neurons: 19.2;Tuft cells: 11.5" "Cell type enhanced" "Detected in all" "oligodendrocyte precursor cell: 114.0" "Cancer enriched" "Detected in many" 5 "Glioblastoma Multiforme (TCGA): 25.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058870 Supported "Golgi apparatus,Plasma membrane" NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 5 "Golgi apparatus, Plasma membrane" "HPA058870: " "unprognostic (1.04e-1)" "unprognostic (4.18e-2)" "unprognostic (1.09e-1)" "unprognostic (1.77e-2)" "unprognostic (5.50e-2)" "unprognostic (1.88e-1)" "unprognostic (4.87e-2)" "potential prognostic unfavorable (7.90e-4)" "unprognostic (2.86e-2)" "unprognostic (5.38e-2)" "unprognostic (1.97e-2)" "unprognostic (1.28e-2)" "unprognostic (1.80e-1)" "unprognostic (2.17e-1)" "unprognostic (1.13e-2)" "unprognostic (5.43e-3)" "unprognostic (2.01e-2)" "unprognostic (1.16e-1)" "unprognostic (1.20e-1)" "unprognostic (2.10e-1)" "unprognostic (6.29e-2)" ASIC2 "ACCN, ACCN1, ASIC2a, BNaC1, BNC1, hBNaC1, MDEG" ENSG00000108684 "Acid sensing ion channel subunit 2" Q16515 17 33013087-34174964 "Plasma proteins, Predicted membrane proteins" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 12.7;cervix: 5.5;endometrium 1: 3.2;retina: 4.2" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 86.2;Brain inhibitory neurons: 116.7;Early spermatids: 115.1;Late spermatids: 192.3;Oligodendrocyte progenitor cells: 290.2;Other brain neurons: 136.5;Respiratory ionocytes: 312.4;Retinal amacrine cells: 208.2;Retinal bipolar cells: 282.9" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 2.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bone cancer: 4.9;Neuroblastoma: 1.7" "Adipose visceral - Mesothelial cells, Skin - Fibroblasts_1, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052112 Enhanced NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 14: Neurons - Synaptic function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 1 "HPA052112: " "unprognostic (1.12e-1)" "unprognostic (5.86e-2)" "unprognostic (3.80e-2)" ASIC3 "ACCN3, DRASIC, TNaC1" ENSG00000213199 "Acid sensing ion channel subunit 3" Q9UHC3 7 151048292-151052756 "Predicted membrane proteins" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 45.0" "Cell type enriched" "Detected in many" 7 "Late spermatids: 111.1" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Glioblastoma Multiforme (TCGA): 6.4;Testicular Germ Cell Tumor (TCGA): 13.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA049155, HPA054805" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 3 "Nucleoplasm, Cytosol" "HPA049155: , HPA054805: " "unprognostic (2.09e-1)" "unprognostic (1.40e-2)" "unprognostic (2.04e-3)" "unprognostic (4.76e-2)" "unprognostic (7.24e-2)" "unprognostic (6.35e-3)" "unprognostic (1.03e-2)" "unprognostic (1.20e-2)" "unprognostic (1.90e-1)" "unprognostic (1.24e-1)" "unprognostic (3.14e-3)" "unprognostic (2.09e-2)" "unprognostic (1.30e-2)" "unprognostic (2.35e-1)" "unprognostic (1.73e-3)" "unprognostic (7.19e-2)" "unprognostic (2.59e-1)" "unprognostic (3.85e-2)" "unprognostic (4.06e-1)" "unprognostic (4.27e-2)" ASIC4 "ACCN4, BNAC4" ENSG00000072182 "Acid sensing ion channel subunit family member 4" Q96FT7 2 219514170-219538772 "Predicted membrane proteins" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 5.9;pituitary gland: 7.4;retina: 6.0" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 21.3;Brain inhibitory neurons: 20.7;Cone photoreceptor cells: 64.2;Corticotrophs: 57.0;Lactotrophs: 98.4;Oligodendrocyte progenitor cells: 72.5;Retinal amacrine cells: 22.5;Retinal bipolar cells: 171.7;Thyrotrophs: 32.5" "Group enriched" "Detected in many" 11 "CGE interneuron: 37.7;committed oligodendrocyte precursor: 53.3;midbrain-derived inhibitory: 93.5;oligodendrocyte precursor cell: 72.7" "Cancer enriched" "Detected in single" 58 "Glioblastoma Multiforme (TCGA): 22.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Leukemia: 2.4;Neuroblastoma: 4.7;Rhabdoid: 1.4" "Adrenal gland - Adrenal medulla cells, Pituitary gland - Lactotropes" "Region enhanced" "Detected in many" "basal ganglia: 73.3" "Low region specificity" "Detected in many" HPA036042 Approved "Golgi apparatus" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "Golgi apparatus" "HPA036042: " "unprognostic (2.37e-1)" "unprognostic (2.21e-3)" ASIC5 "ACCN5, HINAC, INAC" ENSG00000256394 "Acid sensing ion channel subunit family member 5" Q9NY37 4 155829729-155866277 "Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 22 "intestine: 2.2" "Cell type enriched" "Detected in some" 4 "Neuroendocrine cells: 5.6" "Cell type enhanced" "Detected in single" "hippocampal dentate gyrus: 2.0" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA014903, HPA029444" Approved NA NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 56: Non-specific - Sensory perception" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" "HPA014903: , HPA029444: " ASIP "AGTIL, ASP" ENSG00000101440 "Agouti signaling protein" P42127 20 34194569-34269344 "Predicted secreted proteins" Obesity "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "epididymis: 11.5;heart muscle: 23.2;ovary: 34.5" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 92.2;Endometrial stromal cells: 36.6;Epicardial cells: 45.5;Epididymal principal cells: 86.1;Granulosa cells: 38.1;Leydig cells: 40.1;Ovarian stromal cells: 138.5;pDCs: 52.9;Peritubular myoid cells: 40.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 340 "plasmacytoid DC: 125.9" "Lineage enriched" "Detected in single" 340 "dendritic cells: 125.9" "Cancer enhanced" "Detected in many" "Bone cancer: 4.5" "Heart muscle - Cardiomyocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA048636 Uncertain Approved "Vesicles,Flagellar centriole,Mid piece" "Secreted to blood" "No annotated function" NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 75: Ovary - Mixed function" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 94: Gonadal somatic cells - Mixed function" Vesicles "Flagellar centriole, Mid piece" "HPA048636: " "unprognostic (2.72e-3)" "unprognostic (2.10e-1)" "unprognostic (3.75e-1)" "unprognostic (2.50e-1)" "unprognostic (5.12e-1)" "validated prognostic unfavorable (6.10e-6)" "validated prognostic unfavorable (2.34e-4)" "unprognostic (4.80e-2)" "unprognostic (1.95e-1)" "unprognostic (1.31e-2)" "unprognostic (4.17e-3)" "unprognostic (7.98e-2)" "unprognostic (7.89e-2)" ASL ASAL ENSG00000126522 "Argininosuccinate lyase" P04424 7 66075800-66094697 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Arginine biosynthesis, Urea cycle" Lyase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "liver: 356.0" "Cell type enhanced" "Detected in many" "Colonocytes: 239.8;Enteric transient amplifying cells: 131.6;Enterocytes: 239.4;Hepatocytes: 343.9;Tuft cells: 126.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003696, HPA016646" Enhanced Approved Cytosol NA NA 15000000 "Cluster 25: Non-specific - Unknown function" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 44: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 65: Non-specific - Cell growth & division" 3 Cytosol "CAB003696: , HPA016646: " "unprognostic (3.80e-2)" "unprognostic (2.59e-2)" "unprognostic (1.34e-1)" "unprognostic (7.68e-3)" "unprognostic (1.55e-2)" "unprognostic (1.89e-2)" "unprognostic (6.36e-3)" "unprognostic (6.51e-2)" "unprognostic (6.77e-2)" "unprognostic (2.30e-1)" "potential prognostic favorable (2.48e-6)" "unprognostic (1.43e-1)" "unprognostic (1.09e-2)" "unprognostic (1.98e-1)" "unprognostic (1.79e-2)" "unprognostic (2.09e-1)" "unprognostic (7.44e-2)" "unprognostic (2.91e-3)" "unprognostic (2.37e-1)" "unprognostic (2.09e-3)" "unprognostic (2.61e-1)" "unprognostic (2.22e-2)" "unprognostic (1.75e-1)" "unprognostic (1.94e-1)" "unprognostic (2.53e-1)" "unprognostic (7.13e-2)" "unprognostic (3.09e-1)" "unprognostic (4.45e-1)" "unprognostic (2.85e-1)" "unprognostic (1.39e-1)" "unprognostic (3.99e-3)" ASMT "ASMTY, HIOMT, HIOMTY" ENSG00000196433 "Acetylserotonin O-methyltransferase" P46597 X 1615059-1643081 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Melatonin biosynthesis" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "choroid plexus: 7.2" "Cell type enhanced" "Detected in some" "Cholangiocytes: 2.0;Epicardial cells: 2.3;Epididymal clear cells: 4.1;Epididymal principal cells: 2.2;Extravillous trophoblasts: 2.7;Neutrophils: 2.0;Oocytes: 4.6;Retinal horizontal cells: 2.0;Thymocytes: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "naive B-cell: 2.1" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 8 "Brain cancer: 2.3;lymphoma: 2.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 29: Neutrophils - Innate immune cellular maintenance" "unprognostic (2.58e-1)" ASMTL ENSG00000169093 "Acetylserotonin O-methyltransferase like" O95671 X 1403139-1453762 "Enzymes, Predicted intracellular proteins" "Nucleotide metabolism" "Hydrolase, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epicardial cells: 145.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003630, HPA021865" Supported Enhanced Cytosol NA NA 8300 "Cluster 22: Eosinophils - Transcription" "Cluster 75: Ovary - Mixed function" "Cluster 44: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 82: Dendritic cells - Antigen presentation" 11 Cytosol "HPA003630: , HPA021865: " "unprognostic (2.51e-1)" "unprognostic (1.82e-1)" "unprognostic (1.20e-2)" "unprognostic (6.29e-3)" "unprognostic (3.64e-2)" "unprognostic (1.34e-2)" "unprognostic (1.11e-1)" "unprognostic (6.26e-2)" "unprognostic (4.50e-1)" "potential prognostic favorable (5.59e-6)" "unprognostic (3.90e-2)" "unprognostic (2.71e-1)" "unprognostic (1.60e-1)" "unprognostic (1.73e-1)" "unprognostic (7.25e-2)" "unprognostic (6.93e-2)" "unprognostic (1.97e-1)" "unprognostic (2.92e-1)" "unprognostic (4.50e-3)" "unprognostic (1.01e-2)" "unprognostic (1.48e-1)" "unprognostic (1.35e-2)" "unprognostic (5.09e-2)" "unprognostic (1.15e-1)" "unprognostic (9.06e-2)" "unprognostic (3.55e-2)" "unprognostic (1.80e-1)" "unprognostic (2.56e-1)" "unprognostic (1.86e-2)" ASNS ENSG00000070669 "Asparagine synthetase (glutamine-hydrolyzing)" P08243 7 97851677-97872542 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Asparagine biosynthesis" Ligase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 114.4" "Cell type enhanced" "Detected in some" "Astrocytes: 18.6;Bergmann glia: 16.0;Brain excitatory neurons: 59.7;Brain inhibitory neurons: 50.2;Choroid plexus epithelial cells: 13.1;Ependymal cells: 11.4;Loop of henle epithelial cells: 9.8;Microglia: 10.0;Oligodendrocyte progenitor cells: 31.0;Oligodendrocytes: 21.4;Other brain neurons: 46.1;Podocytes: 17.3;Renal connecting tubule cells: 11.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 6 "B-cells: 9.0;T-cells: 14.2" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004924, HPA029318, HPA064737" Approved Supported Cytosol No No 110000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 70: Non-specific - Protein processing" "Cluster 37: Neurons - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 98: Neurons - Neurotransmission & signaling" 14 Cytosol "HPA004924: , HPA029318: , HPA064737: " "unprognostic (3.74e-1)" "unprognostic (3.27e-2)" "unprognostic (3.57e-2)" "unprognostic (2.88e-1)" "unprognostic (4.12e-2)" "unprognostic (4.68e-3)" "unprognostic (1.67e-1)" "unprognostic (2.72e-1)" "potential prognostic unfavorable (9.03e-5)" "unprognostic (2.45e-3)" "potential prognostic unfavorable (9.15e-8)" "unprognostic (9.14e-3)" "unprognostic (9.02e-2)" "potential prognostic unfavorable (8.91e-6)" "unprognostic (5.99e-2)" "unprognostic (7.18e-2)" "unprognostic (3.74e-3)" "unprognostic (4.73e-2)" "unprognostic (1.61e-2)" "unprognostic (9.70e-2)" "unprognostic (2.97e-2)" "unprognostic (1.45e-2)" "unprognostic (1.29e-1)" "unprognostic (6.65e-3)" "unprognostic (1.16e-2)" "unprognostic (5.07e-1)" "unprognostic (9.91e-2)" "unprognostic (7.01e-2)" "unprognostic (3.91e-1)" "unprognostic (1.44e-2)" "unprognostic (1.33e-1)" ASNSD1 "FLJ20752, NBLA00058, NS3TP1" ENSG00000138381 "Asparagine synthetase domain containing 1" Q9NWL6 2 189661385-189670831 "Predicted intracellular proteins" "Amino-acid biosynthesis, Asparagine biosynthesis" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 113.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036132, HPA036133, HPA075042" Approved Approved Cytosol NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 16: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" Cytosol "HPA036132: , HPA036133: , HPA075042: " "unprognostic (7.84e-2)" "unprognostic (2.52e-3)" "unprognostic (3.12e-1)" "unprognostic (1.50e-1)" "unprognostic (2.17e-1)" "unprognostic (4.19e-1)" "unprognostic (1.21e-1)" "unprognostic (2.21e-1)" "unprognostic (3.53e-2)" "unprognostic (8.56e-3)" "validated prognostic favorable (1.82e-6)" "validated prognostic favorable (5.85e-4)" "unprognostic (1.49e-1)" "validated prognostic unfavorable (1.37e-4)" "validated prognostic unfavorable (5.56e-4)" "unprognostic (2.73e-1)" "unprognostic (3.69e-1)" "unprognostic (3.06e-1)" "unprognostic (3.08e-1)" "unprognostic (1.46e-1)" "unprognostic (9.63e-2)" "unprognostic (3.62e-1)" "unprognostic (2.39e-1)" "unprognostic (2.12e-3)" "unprognostic (1.65e-2)" "unprognostic (1.31e-1)" "unprognostic (8.89e-3)" "unprognostic (7.05e-2)" "unprognostic (4.03e-1)" "unprognostic (3.63e-2)" "unprognostic (2.83e-1)" ASPA "ACY2, ASP" ENSG00000108381 Aspartoacylase P45381 17 3472374-3503405 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.0;kidney: 35.6" "Cell type enhanced" "Detected in many" "Bergmann glia: 78.2;Enterocytes: 78.7;Fibro-adipogenic progenitors: 77.6;Leydig cells: 112.6;Melanocytes: 104.0;Myonuclei: 65.5;Oligodendrocytes: 338.6;Peritubular myoid cells: 85.0;Proximal tubule cells: 177.5;Renal collecting duct principal cells: 82.8;Schwann cells: 96.1" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 105.4;oligodendrocyte: 414.7" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 20.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in some" "Adrenal gland - Fibroblasts, Colon - Enteric glia cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Minor Salivary Gland - Fibroblasts, Prostate - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022142, HPA022145" Enhanced Supported Cytosol NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 80: Oligodendrocytes - Myelination" 8 Cytosol "HPA022142: , HPA022145: " "potential prognostic favorable (4.74e-4)" "unprognostic (1.86e-2)" "unprognostic (1.44e-1)" "unprognostic (7.68e-2)" "unprognostic (1.87e-2)" "unprognostic (1.43e-3)" "potential prognostic favorable (5.07e-4)" "potential prognostic favorable (3.01e-6)" "unprognostic (5.27e-3)" "unprognostic (1.81e-2)" "unprognostic (3.61e-2)" "unprognostic (4.02e-1)" "unprognostic (1.26e-1)" "unprognostic (3.72e-2)" "unprognostic (1.83e-3)" "unprognostic (1.82e-1)" "unprognostic (2.91e-2)" "unprognostic (6.66e-2)" ASPDH ENSG00000204653 "Aspartate dehydrogenase domain containing" A6ND91 19 50511600-50514690 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 40.3;kidney: 38.2;liver: 129.1" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 175.3" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in some" 11 "Liver Hepatocellular Carcinoma (TCGA): 49.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 8.3" "Adrenal gland - Adrenal medulla cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA042631, HPA042654" Approved Approved Nucleoplasm,Cytosol NA NA 150000 "Cluster 36: Brain & Liver - Signaling" "Cluster 37: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 93: Hepatocytes - Bile production & excretion" Nucleoplasm Cytosol "HPA042631: , HPA042654: " "unprognostic (8.57e-2)" "unprognostic (2.44e-1)" "unprognostic (6.43e-3)" "unprognostic (1.37e-1)" "potential prognostic favorable (5.77e-5)" "unprognostic (3.60e-2)" "unprognostic (2.62e-2)" "unprognostic (8.21e-3)" "potential prognostic favorable (1.01e-4)" "unprognostic (1.41e-2)" "unprognostic (7.16e-2)" "unprognostic (9.60e-3)" "unprognostic (6.21e-2)" ASPG "C14orf76, hASNase1, LysoLP" ENSG00000166183 Asparaginase Q86U10 14 104085686-104115582 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 97.9;liver: 142.8" "Cell type enriched" "Detected in many" 5 "Esophageal apical cells: 1153.4" "Cell type enhanced" "Detected in some" "deep-layer near-projecting: 6.2" "Group enriched" "Detected in many" 4 "Bladder Urothelial Carcinoma (TCGA): 7.2;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 13.2;Head and Neck Squamous Cell Carcinoma (TCGA): 11.9;Kidney Renal Clear Cell Carcinoma (TCGA): 17.2;Liver Hepatocellular Carcinoma (TCGA): 23.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 3.0" "Adipose visceral - Mesothelial cells, Kidney - Proximal tubular cells, Pituitary gland - Somatotropes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA069761 Enhanced NA NA "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 84: Apical squamous epithelium - Cornification" 12 "HPA069761: " "unprognostic (6.90e-2)" "unprognostic (2.48e-2)" "potential prognostic favorable (1.88e-4)" "unprognostic (2.52e-2)" "unprognostic (1.61e-1)" "validated prognostic favorable (1.96e-4)" "validated prognostic favorable (8.09e-4)" "unprognostic (1.94e-1)" "unprognostic (2.28e-2)" "unprognostic (4.53e-3)" "unprognostic (5.74e-2)" "unprognostic (5.58e-3)" "unprognostic (7.56e-3)" "unprognostic (1.04e-1)" "unprognostic (4.54e-2)" "unprognostic (2.41e-1)" "unprognostic (2.86e-2)" "unprognostic (1.10e-1)" "unprognostic (4.46e-2)" "unprognostic (1.78e-2)" ASPH "BAH, CASQ2BP1, HAAH, JCTN" ENSG00000198363 "Aspartate beta-hydroxylase" Q12797 8 61500556-61714640 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Dioxygenase, Oxidoreductase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 362.0" "Cell type enhanced" "Detected in all" "Adipocytes: 1583.1;Neutrophil progenitors: 899.7;Neutrophils: 2305.7;Ocular epithelial cells: 1020.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 34.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055161, HPA059303" Uncertain Enhanced "Endoplasmic reticulum" NA NA 850000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 7: Liver cancer - Metabolism" "Cluster 24: Neutrophils - Innate immunity signal integration" 77 "Endoplasmic reticulum" "HPA055161: , HPA059303: " "unprognostic (2.94e-2)" "unprognostic (1.80e-2)" "unprognostic (1.21e-1)" "potential prognostic unfavorable (9.40e-7)" "unprognostic (2.05e-1)" "unprognostic (2.56e-2)" "unprognostic (1.84e-1)" "unprognostic (4.53e-1)" "unprognostic (2.37e-2)" "unprognostic (5.99e-3)" "unprognostic (2.04e-2)" "unprognostic (1.50e-2)" "potential prognostic unfavorable (5.81e-6)" "unprognostic (2.33e-2)" "unprognostic (1.40e-3)" "potential prognostic unfavorable (3.07e-5)" "unprognostic (1.82e-1)" "unprognostic (7.08e-2)" "unprognostic (1.12e-1)" "unprognostic (9.13e-2)" "unprognostic (9.51e-3)" "potential prognostic unfavorable (4.57e-5)" "unprognostic (9.22e-3)" "unprognostic (1.67e-1)" "unprognostic (6.92e-2)" "unprognostic (3.04e-1)" "unprognostic (3.03e-2)" "unprognostic (3.03e-1)" "unprognostic (1.44e-1)" "unprognostic (1.14e-3)" "unprognostic (1.16e-1)" ASPHD1 ENSG00000174939 "Aspartate beta-hydroxylase domain containing 1" Q5U4P2 16 29900375-29919864 "Predicted intracellular proteins, Predicted membrane proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 189.4" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 58.0;Epicardial cells: 113.7;Mesothelial cells: 65.0;Neuroendocrine cells: 53.1;Pancreatic islet cells: 86.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Somatotropes, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045175 Uncertain NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 6: Non-specific - Immune response" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 1 "HPA045175: " "unprognostic (1.02e-1)" "unprognostic (9.77e-2)" "unprognostic (3.24e-1)" "unprognostic (5.27e-2)" "potential prognostic unfavorable (1.75e-4)" "unprognostic (2.60e-1)" "potential prognostic unfavorable (1.33e-4)" "unprognostic (6.80e-2)" "unprognostic (9.54e-2)" "unprognostic (2.81e-2)" "unprognostic (1.49e-1)" "unprognostic (2.76e-1)" "unprognostic (2.90e-2)" "unprognostic (3.04e-2)" "potential prognostic unfavorable (5.88e-4)" "unprognostic (3.53e-1)" "unprognostic (6.37e-3)" "unprognostic (2.54e-1)" "unprognostic (2.25e-3)" "unprognostic (3.90e-2)" "unprognostic (5.92e-2)" "unprognostic (2.49e-3)" "unprognostic (7.07e-2)" "unprognostic (7.27e-2)" "unprognostic (1.97e-1)" "unprognostic (1.98e-2)" "unprognostic (2.05e-2)" "unprognostic (6.37e-2)" "unprognostic (1.34e-1)" "unprognostic (2.83e-1)" "unprognostic (5.79e-3)" ASPHD2 FLJ39838 ENSG00000128203 "Aspartate beta-hydroxylase domain containing 2" Q6ICH7 22 26429260-26445015 "Predicted membrane proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.6;skin 1: 10.4" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 26.5;Brain inhibitory neurons: 29.1;cDC: 17.3;Early spermatids: 35.0;Epididymal principal cells: 22.6;Extravillous trophoblasts: 23.9;Foveolar cells: 36.9;Late spermatids: 34.6;Other brain neurons: 17.3;Retinal bipolar cells: 25.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 5.3" "Group enriched" "Detected in many" 4 "dendritic cells: 2.2;monocytes: 5.3" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (granular), Stomach - Gastric mucous cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000820 Uncertain NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 27: Cerebellum - Synaptic function" "Cluster 33: Neurons - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 35: Neurons - Synaptic function & neurogenesis" 3 "HPA000820: " "unprognostic (8.23e-2)" "unprognostic (2.64e-1)" "unprognostic (4.72e-2)" "unprognostic (1.60e-1)" "unprognostic (1.05e-2)" "unprognostic (3.90e-2)" "unprognostic (2.52e-1)" "unprognostic (3.94e-1)" "unprognostic (2.50e-2)" "unprognostic (1.36e-1)" "potential prognostic unfavorable (1.16e-4)" "unprognostic (1.81e-1)" "unprognostic (2.82e-3)" "unprognostic (1.27e-1)" "unprognostic (1.18e-1)" "unprognostic (2.82e-1)" "unprognostic (2.07e-1)" "unprognostic (5.84e-2)" "unprognostic (2.59e-2)" "unprognostic (1.58e-1)" "potential prognostic favorable (2.78e-4)" "unprognostic (1.57e-1)" "unprognostic (4.60e-2)" "unprognostic (3.59e-1)" "unprognostic (1.69e-1)" "unprognostic (1.12e-1)" "unprognostic (1.65e-1)" "unprognostic (3.49e-2)" "unprognostic (1.37e-1)" ASPM "ASP, Calmbp1, FLJ10517, FLJ10549, MCPH5" ENSG00000066279 "Assembly factor for spindle microtubules" Q8IZT6 1 197084121-197146694 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Calmodulin-binding "Cancer-related genes, Disease variant, Intellectual disability, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 9.5;lymphoid tissue: 15.8" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 82.1;Early primary spermatocytes: 51.0;Enteric transient amplifying cells: 59.5;Erythrocyte progenitors: 282.6;Megakaryocyte progenitors: 172.3;Monocyte progenitors: 382.4;Neutrophil progenitors: 111.0;Oocytes: 59.9" "Cell type enhanced" "Detected in many" "deep-layer near-projecting: 10.4;LAMP5-LHX6 and Chandelier: 15.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB017816 Approved "Plasma membrane,Cytosol" NA Yes "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 45: Non-specific - Nuclear processes" "Cluster 27: Non-specific - Cell proliferation" 14 "Plasma membrane, Cytosol" "CAB017816: " "unprognostic (3.99e-2)" "unprognostic (1.50e-1)" "unprognostic (1.12e-1)" "unprognostic (2.17e-2)" "unprognostic (4.80e-1)" "unprognostic (5.73e-2)" "unprognostic (1.50e-1)" "unprognostic (3.96e-2)" "unprognostic (8.32e-2)" "potential prognostic unfavorable (7.81e-6)" "unprognostic (1.09e-3)" "potential prognostic unfavorable (1.53e-5)" "potential prognostic unfavorable (6.44e-5)" "unprognostic (7.39e-3)" "unprognostic (3.95e-3)" "unprognostic (1.52e-1)" "unprognostic (6.88e-2)" "unprognostic (5.62e-2)" "potential prognostic unfavorable (2.70e-4)" "unprognostic (1.11e-3)" "unprognostic (2.10e-3)" "unprognostic (4.73e-2)" "unprognostic (7.54e-2)" "unprognostic (7.96e-2)" "unprognostic (2.62e-1)" "unprognostic (1.04e-1)" ASPN "FLJ20129, PLAP-1, SLRR1C" ENSG00000106819 Asporin Q9BXN1 9 92456205-92482506 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Biomineralization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 129.3;heart muscle: 89.2;smooth muscle: 103.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 67.5;Cardiomyocytes: 39.2;Epicardial cells: 127.4;Fibro-adipogenic progenitors: 86.8;Fibroblasts: 70.0;Hepatic stellate cells: 180.7;Myonuclei: 44.5;Pericytes: 79.5;Retinal ganglion cells: 57.9;Vascular smooth muscle cells: 45.9" "Group enriched" "Detected in all" 6 "fibroblast: 201.0;pericyte: 63.3" "Cancer enhanced" "Detected in all" "Breast Invasive Carcinoma (TCGA): 84.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "basophil: 1.8" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.8" "Cancer enhanced" "Detected in single" "Brain cancer: 1.0" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Fibroblasts, Colon - Enteric glia cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Minor Salivary Gland - Fibroblasts, Pituitary gland - Fibroblasts, Skeletal muscle - Fibroblasts, Spleen - Smooth muscle cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007894, HPA008435, HPA024230" Approved Uncertain Nucleoplasm,Cytosol "Secreted to extracellular matrix" Other NA NA 1100000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 25: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" Nucleoplasm Cytosol "HPA007894: , HPA008435: , HPA024230: " "potential prognostic favorable (5.89e-4)" "unprognostic (2.78e-1)" "unprognostic (1.88e-1)" "unprognostic (6.60e-2)" "unprognostic (2.02e-3)" "unprognostic (9.52e-2)" "unprognostic (6.09e-2)" "unprognostic (6.37e-3)" "unprognostic (2.01e-2)" "potential prognostic unfavorable (2.58e-4)" "unprognostic (1.01e-1)" "unprognostic (3.12e-2)" "potential prognostic unfavorable (2.46e-5)" "unprognostic (9.84e-3)" "unprognostic (1.55e-2)" "unprognostic (1.60e-1)" "unprognostic (2.02e-2)" "unprognostic (2.70e-1)" "unprognostic (3.87e-2)" "unprognostic (1.21e-1)" "potential prognostic unfavorable (1.24e-4)" "unprognostic (6.88e-2)" "unprognostic (1.92e-2)" "unprognostic (3.34e-2)" "unprognostic (3.69e-2)" "unprognostic (2.24e-2)" "unprognostic (1.18e-1)" "potential prognostic unfavorable (2.54e-4)" "unprognostic (5.01e-2)" "unprognostic (7.23e-3)" "unprognostic (9.37e-2)" ASPRV1 "FLJ25084, SASPase, Taps" ENSG00000244617 "Aspartic peptidase retroviral like 1" Q53RT3 2 69960089-69961631 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Aspartyl protease, Hydrolase, Protease" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 25 "skin 1: 614.8" "Cell type enhanced" "Detected in some" "Astrocytes: 2.8;Bergmann glia: 1.8;Brain excitatory neurons: 1.0;Brain inhibitory neurons: 1.5;Ependymal cells: 1.7;Foveolar cells: 1.2;Oligodendrocyte progenitor cells: 3.4;Oligodendrocytes: 4.4;Other brain neurons: 1.3;Podocytes: 1.8" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 7 "Head and Neck Squamous Cell Carcinoma (TCGA): 31.1;Skin Cutaneous Melanoma (TCGA): 53.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "neutrophil: 10.8" "Lineage enriched" "Detected in many" 10 "granulocytes: 10.8" "Cancer enhanced" "Detected in some" "head and neck cancer: 5.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" "HPA034809, HPA034810" Enhanced Approved Cytosol NA NA 720000 "Cluster 35: Neutrophils - Protein binding" "Cluster 37: Skin - Keratinization" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 80: Oligodendrocytes - Myelination" 4 Cytosol "HPA034809: , HPA034810: " "unprognostic (1.29e-2)" "unprognostic (9.56e-3)" "unprognostic (1.28e-2)" "unprognostic (8.04e-2)" "unprognostic (4.71e-1)" "unprognostic (1.51e-2)" "unprognostic (2.04e-2)" "potential prognostic favorable (2.31e-4)" "unprognostic (1.28e-1)" "unprognostic (6.59e-3)" "unprognostic (1.20e-1)" "unprognostic (1.60e-1)" "unprognostic (2.11e-2)" "unprognostic (8.10e-2)" "unprognostic (1.63e-1)" "unprognostic (7.54e-2)" ASPSCR1 "ASPL, ASPS, TUG, UBXD9, UBXN9" ENSG00000169696 "ASPSCR1 tether for SLC2A4, UBX domain containing" Q9BZE9 17 81976807-82017406 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 389.3;Late spermatids: 145.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026749 Approved Supported "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 6: Non-specific - Immune response" "Cluster 70: DU4475 - Unknown function" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 24 Nucleoplasm "Vesicles, Plasma membrane" "HPA026749: " "unprognostic (3.62e-1)" "unprognostic (1.87e-1)" "unprognostic (2.65e-1)" "unprognostic (4.23e-1)" "unprognostic (1.39e-1)" "unprognostic (4.66e-2)" "unprognostic (1.21e-1)" "unprognostic (2.10e-2)" "unprognostic (7.87e-3)" "potential prognostic unfavorable (4.31e-5)" "potential prognostic unfavorable (8.28e-8)" "unprognostic (2.02e-3)" "unprognostic (3.61e-1)" "unprognostic (2.93e-1)" "unprognostic (1.65e-1)" "unprognostic (6.44e-2)" "unprognostic (2.09e-2)" "unprognostic (1.35e-1)" "unprognostic (1.16e-1)" "unprognostic (3.36e-2)" "unprognostic (2.49e-2)" "potential prognostic favorable (5.97e-4)" "unprognostic (1.81e-1)" "unprognostic (1.16e-1)" "unprognostic (8.84e-2)" "unprognostic (5.58e-2)" "unprognostic (2.99e-1)" "unprognostic (9.20e-2)" "unprognostic (2.31e-1)" "unprognostic (3.27e-1)" "unprognostic (1.03e-1)" ASRGL1 "ALP, ALP1, FLJ22316" ENSG00000162174 "Asparaginase and isoaspartyl peptidase 1" Q7L266 11 62337448-62393412 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 123.8;cervix: 114.4;testis: 93.5" "Cell type enhanced" "Detected in many" "Early spermatids: 337.0;Endometrial ciliated cells: 384.2;Endometrial glandular cells: 452.0;Endometrial luminal cells: 518.2;Epididymal efferent duct absorptive cells: 668.0;Fallopian secretory cells: 324.9;Fallopian tube ciliated cells: 478.2;Late primary spermatocytes: 1172.3;Late spermatids: 893.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Uterine Corpus Endometrial Carcinoma (TCGA): 232.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 279.2;eosinophil: 270.3" "Lineage enriched" "Detected in all" 4 "granulocytes: 279.2" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029725, HPA055572, CAB070192" Enhanced Approved "Nucleoplasm,Microtubules,Cytokinetic bridge" Yes NA "Cluster 22: Eosinophils - Transcription" "Cluster 36: Brain & Liver - Signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" Microtubules "Nucleoplasm, Cytokinetic bridge" "CAB070192: , HPA029725: , HPA055572: " "unprognostic (1.43e-2)" "unprognostic (1.08e-1)" "unprognostic (3.39e-1)" "unprognostic (2.24e-2)" "unprognostic (1.82e-2)" "unprognostic (9.04e-2)" "unprognostic (1.65e-1)" "unprognostic (1.03e-3)" "unprognostic (5.53e-2)" "unprognostic (1.05e-1)" "potential prognostic favorable (2.11e-8)" "unprognostic (9.05e-3)" "potential prognostic favorable (4.71e-6)" "potential prognostic unfavorable (4.14e-4)" "unprognostic (1.00e-3)" "unprognostic (2.12e-2)" "unprognostic (3.39e-1)" "unprognostic (2.35e-1)" "unprognostic (1.86e-2)" "unprognostic (9.16e-2)" "unprognostic (1.75e-1)" "unprognostic (4.31e-1)" "unprognostic (8.29e-3)" "unprognostic (3.61e-1)" "unprognostic (1.09e-1)" "unprognostic (8.18e-3)" "unprognostic (1.81e-1)" "unprognostic (1.03e-1)" "unprognostic (2.25e-1)" "unprognostic (1.73e-1)" "unprognostic (1.78e-2)" ASS1 "ASS, CTLN1" ENSG00000130707 "Argininosuccinate synthase 1" P00966 9 130444961-130501274 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Arginine biosynthesis, Urea cycle" Ligase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "kidney: 1200.9;liver: 1907.1" "Cell type enhanced" "Detected in many" "Colonocytes: 290.0;Cytotrophoblasts: 239.4;Enterocytes: 617.9;Epididymal principal cells: 269.1;Hepatocytes: 1156.7;Prostatic club cells: 336.6;Prostatic hillock cells: 398.8;Proximal tubule cells: 453.0;Urothelial cells: 407.9" "Cell type enhanced" "Detected in many" "fibroblast: 42.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 15 "plasmacytoid DC: 1.5" "Lineage enriched" "Detected in single" 15 "dendritic cells: 1.5" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Macrophages, Kidney - Proximal tubular cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Urothelial cells, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020896, HPA020934" Enhanced Supported Nucleoplasm,Cytosol No No 5500000 "Cluster 16: Liver & Kidney - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 40 Cytosol Nucleoplasm "HPA020896: , HPA020934: " "unprognostic (4.68e-2)" "unprognostic (2.61e-2)" "unprognostic (1.52e-2)" "unprognostic (2.52e-2)" "unprognostic (9.73e-2)" "unprognostic (1.69e-1)" "unprognostic (1.73e-1)" "unprognostic (1.01e-2)" "unprognostic (4.27e-3)" "unprognostic (3.34e-1)" "unprognostic (1.35e-3)" "unprognostic (2.77e-1)" "unprognostic (1.94e-1)" "unprognostic (7.62e-3)" "unprognostic (2.32e-2)" "unprognostic (9.92e-3)" "unprognostic (1.63e-1)" "unprognostic (2.26e-1)" "unprognostic (1.90e-1)" "unprognostic (5.63e-3)" "unprognostic (1.41e-1)" "unprognostic (3.86e-2)" "unprognostic (3.39e-3)" "unprognostic (1.49e-1)" "unprognostic (7.40e-3)" "unprognostic (1.53e-1)" "unprognostic (5.30e-2)" "unprognostic (2.38e-2)" "unprognostic (3.27e-2)" "unprognostic (5.83e-2)" "unprognostic (3.85e-2)" ASTE1 HT001 ENSG00000034533 "Asteroid homolog 1" Q2TB18 3 131013875-131027649 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 53.5;Epicardial cells: 66.0;Late primary spermatocytes: 42.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037010, HPA037011" Supported Approved "Endoplasmic reticulum" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 1 "Endoplasmic reticulum" "HPA037010: , HPA037011: " "unprognostic (2.32e-1)" "unprognostic (4.13e-2)" "unprognostic (1.37e-1)" "unprognostic (6.62e-2)" "unprognostic (9.94e-3)" "unprognostic (5.77e-2)" "unprognostic (2.43e-1)" "unprognostic (9.77e-2)" "unprognostic (1.65e-2)" "unprognostic (2.75e-2)" "unprognostic (3.07e-3)" "unprognostic (1.47e-1)" "unprognostic (2.83e-1)" "potential prognostic unfavorable (7.50e-5)" "unprognostic (2.31e-2)" "unprognostic (2.90e-1)" "unprognostic (2.42e-1)" "unprognostic (5.56e-3)" "unprognostic (4.07e-2)" "unprognostic (1.95e-1)" "unprognostic (9.80e-2)" "unprognostic (1.33e-1)" "unprognostic (7.21e-2)" "unprognostic (9.33e-2)" "unprognostic (8.38e-3)" "unprognostic (1.79e-1)" "unprognostic (1.61e-3)" "unprognostic (2.11e-1)" "unprognostic (4.91e-1)" "unprognostic (1.72e-2)" "unprognostic (1.46e-1)" ASTL "ovastacin, SAS1B" ENSG00000188886 "Astacin like metalloendopeptidase" Q6HA08 2 96122818-96138502 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Fertilization "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 3.7" "Cell type enhanced" "Detected in many" "cDC: 56.3;Endometrial glandular cells: 52.5;Endometrial luminal cells: 72.1;Innate lymphoid cells: 56.9;Macrophages: 36.1;monocytes: 43.5;NK-cells: 55.2;pDCs: 40.7;Plasma cells: 39.5;Prostatic hillock cells: 27.0;T-cells: 42.5;Thymocytes: 28.8;Urothelial cells: 25.4" "Cell type enriched" "Detected in some" 8 "leukocyte: 12.7" "Cancer enhanced" "Detected in single" "Ovary Serous Cystadenocarcinoma (TCGA): 1.2" "Region enriched" "Detected in some" 5 "cerebral cortex: 7.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA015620 Uncertain "Intracellular and membrane" Enzyme NA NA "Cluster 15: Bone marrow - Innate immune response" "Cluster 53: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 3 "HPA015620: " "unprognostic (4.77e-2)" "unprognostic (9.25e-2)" ASTN1 ASTN ENSG00000152092 "Astrotactin 1" O14525 1 176857302-177164973 "Plasma proteins, Predicted membrane proteins, Transporters" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 14.1;brain: 37.4;retina: 13.0" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 168.2;Astrocytes: 301.6;Brain excitatory neurons: 280.5;Brain inhibitory neurons: 301.3;Corticotrophs: 479.1;Gonadotrophs: 272.5;Lactotrophs: 246.1;Oligodendrocyte progenitor cells: 456.6;Other brain neurons: 207.0;Pituicytes/FSCs: 182.6;Pituitary stem cells: 298.4;Retinal amacrine cells: 343.9;Retinal horizontal cells: 204.3;Rod photoreceptor cells: 145.1;Thyrotrophs: 185.0" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in some" 16 "Glioblastoma Multiforme (TCGA): 32.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 3.4;Neuroblastoma: 4.6" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074112 Approved "Golgi apparatus,Vesicles" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 35: Neurons - Synaptic function & neurogenesis" 1 "Golgi apparatus" Vesicles "HPA074112: " "unprognostic (3.40e-1)" "unprognostic (1.74e-1)" "unprognostic (1.41e-1)" "unprognostic (2.92e-1)" "unprognostic (1.46e-1)" ASTN2 KIAA0634 ENSG00000148219 "Astrotactin 2" O75129 9 116423112-117415070 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 670.1;Astrocytes: 734.8;Ependymal cells: 909.5;Oligodendrocyte progenitor cells: 1333.0;Pituicytes/FSCs: 2079.4;Prostatic glandular cells: 1015.0;Retinal ganglion cells: 1193.6;Sertoli cells: 977.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 56.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Kidney - Fibroblasts, Pituitary gland - Undifferentiated cells (Pituitary gland), Prostate - Prostate glandular cells, Stomach - Chief cells, Testis - Sertoli cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027035 Uncertain Approved Nucleoplasm,Cytosol No No "Cluster 39: T-cells - T-cell receptor" "Cluster 35: Non-specific - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" Cytosol Nucleoplasm "HPA027035: " "unprognostic (9.67e-2)" "unprognostic (1.11e-1)" "unprognostic (2.27e-1)" "unprognostic (2.38e-1)" "unprognostic (1.73e-2)" "unprognostic (4.90e-2)" "unprognostic (3.45e-1)" "unprognostic (3.86e-3)" "unprognostic (1.26e-2)" "unprognostic (3.94e-1)" "validated prognostic favorable (9.13e-7)" "validated prognostic favorable (3.47e-7)" "potential prognostic favorable (2.86e-5)" "unprognostic (1.31e-1)" "unprognostic (4.50e-3)" "unprognostic (4.91e-2)" "unprognostic (3.83e-1)" "unprognostic (8.37e-2)" "unprognostic (2.14e-1)" "unprognostic (1.42e-1)" "unprognostic (1.32e-1)" "unprognostic (1.30e-1)" "unprognostic (3.40e-2)" "unprognostic (1.09e-1)" "unprognostic (3.26e-2)" "unprognostic (7.66e-3)" "unprognostic (3.03e-2)" "unprognostic (2.40e-1)" "unprognostic (1.55e-1)" "unprognostic (1.92e-2)" "unprognostic (4.58e-2)" ASXL1 KIAA0978 ENSG00000171456 "ASXL transcriptional regulator 1" Q8IXJ9 20 32358330-32439319 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Chromatin regulator, Repressor" "Cancer-related genes, Craniosynostosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064156 Approved Nucleoplasm,Nucleoli NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 39: Testis - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 20: Non-specific - Transcription regulation" 55 "Nucleoplasm, Nucleoli" "HPA064156: " "unprognostic (5.85e-2)" "unprognostic (4.24e-1)" "unprognostic (7.68e-2)" "unprognostic (1.46e-1)" "unprognostic (3.23e-1)" "unprognostic (6.36e-2)" "unprognostic (2.79e-1)" "unprognostic (4.43e-3)" "unprognostic (1.66e-2)" "unprognostic (2.37e-2)" "unprognostic (4.98e-2)" "unprognostic (1.41e-2)" "unprognostic (1.36e-1)" "unprognostic (3.71e-3)" "unprognostic (1.28e-1)" "unprognostic (3.49e-1)" "unprognostic (1.10e-2)" "unprognostic (5.07e-2)" "unprognostic (1.85e-2)" "unprognostic (1.63e-1)" "unprognostic (1.69e-2)" "unprognostic (5.96e-2)" "potential prognostic unfavorable (4.45e-4)" "unprognostic (1.52e-1)" "unprognostic (7.35e-3)" "unprognostic (1.64e-2)" "unprognostic (6.75e-2)" "unprognostic (1.74e-1)" "unprognostic (2.17e-1)" "unprognostic (9.81e-2)" "unprognostic (5.60e-3)" ASXL2 "ASXH2, FLJ10898, KIAA1685" ENSG00000143970 "ASXL transcriptional regulator 2" Q76L83 2 25733753-25878487 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" Repressor "Cancer-related genes, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034646, HPA058040" Enhanced Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 9: T-cells - Adaptive immunity: Regulation" 13 Nucleoplasm "HPA034646: , HPA058040: " "unprognostic (2.21e-1)" "unprognostic (1.25e-2)" "unprognostic (2.34e-1)" "unprognostic (1.15e-2)" "unprognostic (1.35e-1)" "unprognostic (9.28e-2)" "unprognostic (4.04e-2)" "unprognostic (3.27e-1)" "unprognostic (4.63e-2)" "unprognostic (5.00e-3)" "validated prognostic favorable (1.25e-6)" "validated prognostic favorable (5.95e-4)" "unprognostic (5.93e-2)" "unprognostic (8.03e-2)" "unprognostic (2.44e-1)" "unprognostic (9.39e-2)" "unprognostic (1.64e-1)" "unprognostic (1.72e-2)" "unprognostic (2.39e-1)" "unprognostic (6.36e-3)" "unprognostic (1.68e-2)" "unprognostic (1.14e-2)" "unprognostic (1.37e-2)" "unprognostic (1.37e-1)" "unprognostic (9.75e-3)" "unprognostic (5.96e-2)" "unprognostic (3.98e-2)" "unprognostic (1.88e-1)" "unprognostic (3.00e-1)" "unprognostic (8.97e-2)" "unprognostic (6.09e-2)" ASXL3 KIAA1713 ENSG00000141431 "ASXL transcriptional regulator 3" Q9C0F0 18 33578219-33751195 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 101.0;Choroid plexus epithelial cells: 136.3;Corticotrophs: 206.8;Distal convoluted tubule cells: 127.4;Early spermatids: 136.6;Oligodendrocyte progenitor cells: 101.2;Other brain neurons: 109.2;Pituitary stem cells: 336.5;Renal collecting duct intercalated cells: 101.9;Renal connecting tubule cells: 147.9;Retinal amacrine cells: 195.5" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 1.5;Neuroblastoma: 1.1;Sarcoma: 1.5" "Adipose subcutaneous - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039539, HPA040034" Uncertain NA NA "Cluster 21: Testis - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 109: Neurons - Neuronal signaling" 4 "HPA039539: , HPA040034: " "unprognostic (2.87e-3)" "unprognostic (1.30e-1)" ASZ1 "ALP1, ANKL1, C7orf7, CT1.19, GASZ, Orf3" ENSG00000154438 "Ankyrin repeat, SAM and basic leucine zipper domain containing 1" Q8WWH4 7 117363222-117428123 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Meiosis, RNA-mediated gene silencing, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 100 "testis: 10.0" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 19.1;Early primary spermatocytes: 130.7;Late primary spermatocytes: 32.4;Oocytes: 9.2;Undifferentiated spermatogonia: 52.2" "Cell type enriched" "Detected in single" 4 "oligodendrocyte: 4.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Spermatocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA020558 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 11: White matter - Signal transduction" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 3: Early primary spermatocytes - Early meiosis" 10 Cytosol Nucleoplasm "HPA020558: " ATAD1 "FLJ14600, Msp1" ENSG00000138138 "ATPase family AAA domain containing 1" Q8NBU5 10 87751512-87841361 "Disease related genes, Human disease related genes, Predicted membrane proteins" Translocase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 1074.7;Late spermatids: 2786.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037569 Uncertain Approved "Nucleoli rim,Mitochondria" NA NA 6400 "Cluster 15: NK-cells - Unknown function" "Cluster 35: Non-specific - Mixed function" "Cluster 14: Neurons - Synaptic function" "Cluster 52: Non-specific - Mitochondria" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 5 "Nucleoli rim" Mitochondria "HPA037569: " "unprognostic (3.19e-1)" "unprognostic (4.13e-2)" "unprognostic (6.22e-2)" "unprognostic (1.70e-2)" "unprognostic (1.56e-1)" "unprognostic (4.57e-3)" "unprognostic (2.15e-2)" "unprognostic (3.40e-3)" "unprognostic (9.07e-3)" "unprognostic (1.14e-1)" "potential prognostic favorable (2.70e-6)" "unprognostic (7.63e-3)" "unprognostic (1.17e-1)" "unprognostic (2.25e-1)" "unprognostic (1.45e-1)" "unprognostic (2.30e-2)" "unprognostic (3.46e-1)" "unprognostic (1.85e-1)" "unprognostic (9.98e-2)" "unprognostic (1.73e-1)" "unprognostic (3.54e-2)" "unprognostic (1.04e-2)" "unprognostic (5.88e-2)" "unprognostic (4.05e-2)" "unprognostic (2.92e-1)" "unprognostic (8.14e-2)" "unprognostic (2.34e-1)" "unprognostic (1.14e-1)" "unprognostic (1.58e-1)" "unprognostic (4.49e-2)" "unprognostic (3.15e-2)" ATAD2 "ANCCA, CT137, DKFZp667N1320, MGC29843, MGC5254, PRO2000" ENSG00000156802 "ATPase family AAA domain containing 2" Q6PL18 8 123319850-123416350 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.0;lymphoid tissue: 26.3" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 168.5;Erythrocyte progenitors: 342.2;Megakaryocyte progenitors: 229.1;Monocyte progenitors: 345.9;Neutrophil progenitors: 319.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Testis - Spermatocytes" "Low region specificity" "Detected in all" "HPA029424, CAB056158" Enhanced Enhanced Nucleoplasm Yes Yes "Cluster 5: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 38: Sub-cortical - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 17 Nucleoplasm "CAB056158: , HPA029424: " "unprognostic (2.11e-1)" "unprognostic (1.51e-1)" "unprognostic (2.34e-1)" "unprognostic (1.49e-1)" "unprognostic (2.29e-1)" "unprognostic (1.20e-2)" "unprognostic (4.27e-1)" "unprognostic (1.37e-1)" "unprognostic (1.31e-1)" "potential prognostic unfavorable (1.83e-4)" "unprognostic (3.16e-2)" "unprognostic (6.17e-2)" "potential prognostic unfavorable (1.04e-9)" "unprognostic (2.72e-2)" "unprognostic (1.21e-3)" "potential prognostic unfavorable (1.57e-4)" "unprognostic (9.64e-3)" "unprognostic (6.30e-2)" "unprognostic (2.27e-1)" "unprognostic (2.03e-1)" "unprognostic (1.92e-2)" "unprognostic (2.99e-3)" "potential prognostic unfavorable (4.41e-4)" "unprognostic (1.53e-2)" "unprognostic (4.51e-2)" "unprognostic (1.45e-1)" "unprognostic (2.78e-2)" "unprognostic (6.43e-2)" "unprognostic (1.63e-1)" "unprognostic (8.91e-2)" "unprognostic (1.71e-2)" ATAD2B KIAA1240 ENSG00000119778 "ATPase family AAA domain containing 2B" Q9ULI0 2 23748664-23927123 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034555 Uncertain Supported Nucleoplasm NA NA "Cluster 41: Basophils - Unknown function" "Cluster 49: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 7: Non-specific - Transcription" 3 Nucleoplasm "HPA034555: " "unprognostic (1.64e-1)" "unprognostic (2.11e-1)" "unprognostic (8.94e-2)" "unprognostic (8.91e-2)" "unprognostic (1.79e-1)" "unprognostic (7.36e-2)" "unprognostic (1.64e-2)" "unprognostic (4.46e-2)" "unprognostic (1.04e-2)" "unprognostic (4.49e-2)" "unprognostic (4.59e-1)" "unprognostic (3.32e-2)" "unprognostic (6.73e-2)" "unprognostic (3.93e-3)" "unprognostic (1.65e-1)" "unprognostic (3.93e-1)" "unprognostic (1.54e-1)" "unprognostic (4.00e-2)" "unprognostic (4.57e-2)" "unprognostic (1.69e-1)" "unprognostic (1.44e-1)" "unprognostic (1.96e-1)" "unprognostic (1.69e-3)" "potential prognostic unfavorable (7.92e-4)" "unprognostic (7.84e-2)" "unprognostic (3.79e-1)" "unprognostic (2.20e-1)" "unprognostic (2.33e-1)" "unprognostic (3.27e-1)" "unprognostic (2.08e-1)" "unprognostic (2.55e-1)" ATAD3A FLJ10709 ENSG00000197785 "ATPase family AAA domain containing 3A" Q9NVI7 1 1512162-1534685 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 62.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058968, HPA064867, HPA065305" Approved Enhanced Mitochondria,Acrosome NA NA 23000 "Cluster 13: Non-specific - Mitochondria" "Cluster 24: Non-specific - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 37: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 37 Mitochondria Acrosome "HPA058968: , HPA064867: , HPA065305: " "unprognostic (2.60e-2)" "unprognostic (1.86e-1)" "unprognostic (5.86e-3)" "unprognostic (2.02e-1)" "unprognostic (1.37e-1)" "unprognostic (3.11e-1)" "unprognostic (1.74e-1)" "unprognostic (5.26e-2)" "unprognostic (3.81e-2)" "unprognostic (2.19e-1)" "unprognostic (3.77e-3)" "unprognostic (4.53e-2)" "unprognostic (5.16e-3)" "validated prognostic unfavorable (5.58e-4)" "validated prognostic unfavorable (3.92e-8)" "unprognostic (1.49e-1)" "unprognostic (5.91e-2)" "unprognostic (4.04e-2)" "unprognostic (2.04e-1)" "unprognostic (7.65e-2)" "unprognostic (2.80e-3)" "unprognostic (1.22e-1)" "unprognostic (3.94e-1)" "unprognostic (3.42e-2)" "unprognostic (7.54e-2)" "unprognostic (5.80e-2)" "unprognostic (1.70e-1)" "unprognostic (6.67e-2)" "unprognostic (1.97e-1)" "unprognostic (2.50e-2)" "unprognostic (8.33e-2)" ATAD3B "KIAA1273, TOB3" ENSG00000160072 "ATPase family AAA domain containing 3B" Q5T9A4 1 1471765-1497848 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 48.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "HPA058968, HPA064867, HPA065305" Approved Supported Mitochondria,Acrosome NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 64: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 24 Mitochondria Acrosome "HPA058968: , HPA064867: , HPA065305: " "unprognostic (2.78e-2)" "unprognostic (1.37e-1)" "unprognostic (2.83e-1)" "unprognostic (3.04e-1)" "unprognostic (9.76e-3)" "unprognostic (5.85e-3)" "unprognostic (2.13e-1)" "unprognostic (4.64e-2)" "unprognostic (4.99e-2)" "unprognostic (1.10e-2)" "potential prognostic unfavorable (5.64e-8)" "unprognostic (1.02e-3)" "unprognostic (2.38e-1)" "potential prognostic unfavorable (6.54e-5)" "unprognostic (3.95e-3)" "unprognostic (1.35e-3)" "unprognostic (1.74e-2)" "unprognostic (5.56e-2)" "potential prognostic favorable (6.30e-4)" "unprognostic (1.24e-1)" "unprognostic (2.31e-3)" "unprognostic (2.26e-2)" "unprognostic (1.24e-2)" "unprognostic (1.65e-1)" "unprognostic (8.42e-2)" "unprognostic (2.78e-2)" "unprognostic (2.98e-1)" "unprognostic (2.78e-2)" "unprognostic (5.02e-3)" ATAD3C FLJ34599 ENSG00000215915 "ATPase family AAA domain containing 3C" Q5T2N8 1 1449689-1470163 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 28.1;Alveolar cells type 2: 27.8;Epididymal clear cells: 22.5;Epididymal efferent duct absorptive cells: 32.7;Oocytes: 59.9;Pancreatic islet cells: 21.5;Plasma cells: 24.8" "Cell type enhanced" "Detected in many" "oligodendrocyte: 15.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in some" "Minor Salivary Gland - Minor salivary glandular cells" HPA065305 Approved Mitochondria NA NA "Cluster 70: Non-specific - Protein processing" "Cluster 11: White matter - Signal transduction" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 67: Plasma cells - Plasma cell differentiation" 3 Mitochondria "HPA065305: " "potential prognostic favorable (4.57e-4)" "unprognostic (1.05e-1)" "unprognostic (3.62e-1)" "unprognostic (1.31e-1)" "unprognostic (6.01e-2)" "unprognostic (5.00e-2)" "unprognostic (6.61e-3)" "unprognostic (5.02e-2)" "unprognostic (3.18e-2)" "unprognostic (8.39e-2)" "unprognostic (5.26e-2)" "unprognostic (2.03e-1)" "potential prognostic favorable (6.94e-4)" "unprognostic (2.01e-1)" "unprognostic (4.49e-2)" "unprognostic (7.72e-3)" "unprognostic (7.03e-2)" "unprognostic (5.72e-2)" "unprognostic (8.52e-2)" "unprognostic (9.67e-2)" "unprognostic (1.35e-1)" "unprognostic (1.82e-1)" "unprognostic (1.91e-3)" "unprognostic (3.14e-1)" "unprognostic (9.60e-2)" "unprognostic (2.41e-1)" "unprognostic (5.07e-2)" "unprognostic (3.22e-1)" "unprognostic (3.91e-2)" "unprognostic (1.43e-1)" "unprognostic (1.49e-1)" ATAD5 "C17orf41, ELG1, FLJ12735, FRAG1" ENSG00000176208 "ATPase family AAA domain containing 5" Q96QE3 17 30831966-30895869 "Essential proteins, Predicted intracellular proteins" "DNA damage" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 11.6" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 105.2;Epicardial cells: 129.6;Erythrocyte progenitors: 322.5;Megakaryocyte progenitors: 119.7;Monocyte progenitors: 155.8;Neutrophil progenitors: 97.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA066823 Approved "Nucleoplasm,Cytokinetic bridge,Centriolar satellite,Cytosol" Yes No "Cluster 14: Non-specific - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 15: Non-specific - Transcription" "Cluster 59: Leukemia - T-cell receptor" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 12 Nucleoplasm "Cytokinetic bridge, Centriolar satellite, Cytosol" "HPA066823: " "unprognostic (1.70e-1)" "unprognostic (6.65e-2)" "unprognostic (5.94e-2)" "unprognostic (1.76e-2)" "unprognostic (1.64e-1)" "unprognostic (2.43e-1)" "unprognostic (3.66e-1)" "unprognostic (6.58e-3)" "unprognostic (1.12e-2)" "unprognostic (8.28e-2)" "unprognostic (1.30e-3)" "unprognostic (1.25e-2)" "unprognostic (4.42e-3)" "unprognostic (2.24e-1)" "unprognostic (8.15e-3)" "unprognostic (1.05e-1)" "unprognostic (2.88e-1)" "potential prognostic unfavorable (5.38e-4)" "unprognostic (1.78e-3)" "unprognostic (1.58e-2)" "unprognostic (4.25e-3)" "unprognostic (2.10e-2)" "unprognostic (3.38e-1)" "unprognostic (7.33e-3)" ATAT1 "C6orf134, Em:AB023049.7, FLJ13158, MEC17" ENSG00000137343 "Alpha tubulin acetyltransferase 1" Q5SQI0 6 30626842-30646823 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 31.4" "Cell type enhanced" "Detected in many" "Astrocytes: 24.1;Bergmann glia: 22.2;Brain inhibitory neurons: 15.7;Choroid plexus epithelial cells: 16.0;Distal convoluted tubule cells: 16.7;Early spermatids: 48.1;Ependymal cells: 25.9;Late primary spermatocytes: 17.7;Late spermatids: 42.0;Loop of henle epithelial cells: 17.6;Oligodendrocyte progenitor cells: 28.3;Oligodendrocytes: 22.2;Other brain neurons: 17.8;Papillary tip epithelial cells: 15.1;Proximal tubule cells: 19.7;Renal collecting duct intercalated cells: 16.6;Renal collecting duct principal cells: 16.2;Renal connecting tubule cells: 20.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 7.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046816, HPA050999" Approved Supported "Golgi apparatus,Cytosol" "Intracellular and membrane" Enzyme No No "Cluster 10: Non-specific - Membrane trafficking" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 102: Non-specific - Mixed function" 4 Cytosol "Golgi apparatus" "HPA046816: , HPA050999: " "unprognostic (1.17e-1)" "unprognostic (6.37e-2)" "unprognostic (2.75e-1)" "unprognostic (5.12e-2)" "unprognostic (1.85e-1)" "unprognostic (1.82e-1)" "unprognostic (1.23e-1)" "unprognostic (1.35e-2)" "unprognostic (1.25e-2)" "unprognostic (3.19e-1)" "unprognostic (3.76e-2)" "unprognostic (2.11e-1)" "unprognostic (1.09e-2)" "unprognostic (3.89e-1)" "unprognostic (1.96e-1)" "unprognostic (2.43e-1)" "unprognostic (6.89e-3)" "unprognostic (1.15e-1)" "unprognostic (1.63e-1)" "unprognostic (1.06e-1)" ATCAY BNIP-H ENSG00000167654 "ATCAY kinesin light chain interacting caytaxin" Q86WG3 19 3879864-3928082 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Neurogenesis, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 78.9;pituitary gland: 24.7;retina: 16.3" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 127.6;Brain excitatory neurons: 81.2;Brain inhibitory neurons: 105.6;Corticotrophs: 60.3;Gonadotrophs: 51.4;Lactotrophs: 72.4;Oligodendrocyte progenitor cells: 174.6;Other brain neurons: 113.1;Retinal amacrine cells: 195.6;Retinal bipolar cells: 170.3;Retinal ganglion cells: 135.2;Retinal horizontal cells: 66.1;Somatotrophs: 56.5;Thyrotrophs: 84.8" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in some" 6 "Glioblastoma Multiforme (TCGA): 27.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "Neuroblastoma: 35.1" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Pancreas - Alpha cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017755 Enhanced NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 4 "HPA017755: " "unprognostic (3.52e-1)" "unprognostic (1.43e-1)" "potential prognostic favorable (1.18e-4)" "potential prognostic favorable (5.02e-4)" "unprognostic (2.17e-2)" "unprognostic (1.00e-1)" "unprognostic (2.39e-2)" "unprognostic (2.10e-1)" "unprognostic (6.24e-2)" ATE1 ENSG00000107669 "Arginyltransferase 1" O95260 10 121709393-121928801 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Choroid plexus epithelial cells: 604.2;Gastric progenitor cells: 725.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038444, HPA057549" Approved Supported Nucleoplasm NA NA 20000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 31: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 7 Nucleoplasm "HPA038444: , HPA057549: " "unprognostic (9.37e-2)" "unprognostic (5.90e-2)" "unprognostic (1.22e-1)" "unprognostic (2.59e-1)" "unprognostic (2.82e-2)" "unprognostic (5.42e-2)" "unprognostic (2.93e-2)" "potential prognostic favorable (8.97e-4)" "unprognostic (1.41e-2)" "unprognostic (1.44e-1)" "validated prognostic favorable (4.80e-8)" "validated prognostic favorable (7.67e-4)" "unprognostic (3.30e-1)" "unprognostic (1.63e-1)" "unprognostic (2.40e-1)" "unprognostic (2.62e-1)" "unprognostic (1.65e-2)" "unprognostic (1.10e-1)" "unprognostic (4.11e-1)" "unprognostic (2.04e-2)" "potential prognostic unfavorable (1.20e-5)" "unprognostic (1.08e-1)" "unprognostic (8.36e-2)" "unprognostic (3.09e-2)" "unprognostic (5.75e-2)" "unprognostic (4.90e-1)" "unprognostic (2.67e-1)" "unprognostic (1.72e-1)" "unprognostic (7.33e-2)" "unprognostic (1.63e-1)" "unprognostic (6.54e-2)" ATF1 TREB36 ENSG00000123268 "Activating transcription factor 1" P18846 12 50763710-50821162 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016222, HPA055069, HPA055406" Supported Enhanced Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - DNA binding" "Cluster 38: Non-specific - Transcription" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 9 Nucleoplasm "CAB016222: , HPA055069: , HPA055406: " "unprognostic (6.90e-2)" "unprognostic (1.03e-2)" "unprognostic (6.69e-2)" "unprognostic (6.90e-2)" "unprognostic (1.35e-1)" "unprognostic (1.33e-1)" "unprognostic (9.66e-2)" "unprognostic (2.98e-1)" "unprognostic (2.24e-1)" "unprognostic (7.07e-2)" "potential prognostic favorable (8.34e-6)" "unprognostic (4.04e-2)" "unprognostic (9.13e-2)" "potential prognostic unfavorable (1.84e-4)" "unprognostic (2.57e-2)" "unprognostic (4.58e-2)" "unprognostic (7.05e-2)" "unprognostic (3.20e-1)" "unprognostic (1.07e-1)" "unprognostic (1.76e-1)" "unprognostic (8.02e-2)" "unprognostic (2.20e-3)" "unprognostic (3.27e-2)" "unprognostic (1.31e-2)" "unprognostic (1.80e-2)" "unprognostic (9.65e-2)" "unprognostic (1.43e-1)" "unprognostic (6.41e-2)" "unprognostic (2.58e-1)" "unprognostic (9.35e-2)" "unprognostic (1.56e-1)" ATF2 "CRE-BP1, CREB2, HB16, TREB7" ENSG00000115966 "Activating transcription factor 2" P15336 2 175072250-175168382 "Predicted intracellular proteins, Transcription factors" "DNA damage, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003769, HPA022134" Supported Supported Supported Nucleoplasm NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 61: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 7: Non-specific - Transcription" 92 Nucleoplasm "CAB003769: , HPA022134: " "unprognostic (3.27e-2)" "unprognostic (8.93e-2)" "unprognostic (3.08e-1)" "unprognostic (1.26e-1)" "unprognostic (3.37e-1)" "unprognostic (5.13e-2)" "unprognostic (1.00e-1)" "unprognostic (9.65e-2)" "unprognostic (2.06e-1)" "potential prognostic unfavorable (3.80e-4)" "potential prognostic favorable (6.98e-6)" "unprognostic (4.39e-3)" "unprognostic (2.07e-3)" "potential prognostic unfavorable (1.37e-5)" "unprognostic (4.19e-2)" "unprognostic (2.00e-1)" "unprognostic (3.77e-1)" "unprognostic (2.41e-1)" "unprognostic (7.79e-2)" "unprognostic (5.12e-2)" "potential prognostic unfavorable (4.42e-4)" "unprognostic (2.02e-2)" "unprognostic (1.24e-3)" "unprognostic (5.19e-2)" "unprognostic (1.73e-1)" "unprognostic (4.84e-2)" "unprognostic (5.73e-2)" "unprognostic (1.13e-2)" "unprognostic (7.96e-2)" "unprognostic (1.71e-2)" "unprognostic (1.56e-1)" ATF3 ENSG00000162772 "Activating transcription factor 3" P18847 1 212565334-212620777 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast secretory cells: 1394.6;Endometrial glandular cells: 1349.7;Endometrial luminal cells: 1837.3;Epididymal basal cells: 1805.0;Epididymal efferent duct absorptive cells: 1270.5;Fallopian secretory cells: 1313.3;Smooth muscle cells: 1236.3" "Group enriched" "Detected in all" 6 "endothelial cell: 116.3;ependymal cell: 62.0;vascular associated smooth muscle cell: 213.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 6.5;non-classical monocyte: 6.4" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 13.2" HPA001562 Approved Supported "Nucleoplasm,Nucleoli,Vesicles,Centrosome,Basal body" Yes Yes "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 11: White matter - Signal transduction" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 52 "Nucleoplasm, Nucleoli, Basal body" "Vesicles, Centrosome" "HPA001562: " "unprognostic (6.77e-2)" "unprognostic (5.03e-2)" "unprognostic (3.92e-2)" "unprognostic (1.13e-1)" "unprognostic (2.61e-2)" "unprognostic (2.03e-1)" "unprognostic (9.19e-2)" "unprognostic (8.15e-2)" "unprognostic (9.02e-2)" "unprognostic (1.62e-1)" "unprognostic (1.26e-2)" "unprognostic (8.11e-3)" "unprognostic (2.23e-1)" "unprognostic (1.74e-1)" "unprognostic (5.19e-2)" "unprognostic (2.88e-1)" "unprognostic (1.37e-1)" "unprognostic (1.25e-1)" "unprognostic (1.76e-1)" "unprognostic (6.51e-3)" "unprognostic (1.31e-1)" "unprognostic (2.63e-2)" "unprognostic (1.88e-2)" "unprognostic (4.11e-1)" "unprognostic (1.23e-1)" "potential prognostic favorable (4.33e-5)" "unprognostic (2.30e-2)" "unprognostic (3.02e-2)" "unprognostic (1.65e-1)" "unprognostic (1.32e-2)" "unprognostic (2.80e-1)" ATF4 "CREB-2, TAXREB67, TXREB" ENSG00000128272 "Activating transcription factor 4" P18848 22 39519695-39522683 "Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epididymal basal cells: 615.2;Esophageal apical cells: 599.5;Platelets: 502.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011596, HPA062987" Approved Supported Nucleoplasm NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 24: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 15: Non-specific - Protein processing" 77 Nucleoplasm "CAB011596: , HPA062987: " "unprognostic (1.15e-1)" "unprognostic (6.21e-2)" "unprognostic (2.44e-1)" "unprognostic (3.28e-2)" "unprognostic (4.40e-2)" "unprognostic (2.32e-2)" "unprognostic (3.91e-2)" "unprognostic (1.24e-1)" "unprognostic (7.17e-3)" "unprognostic (4.35e-2)" "unprognostic (4.05e-2)" "unprognostic (9.74e-2)" "unprognostic (2.99e-2)" "potential prognostic unfavorable (1.83e-4)" "unprognostic (9.32e-3)" "unprognostic (2.30e-1)" "unprognostic (9.31e-2)" "unprognostic (1.64e-2)" "unprognostic (4.32e-2)" "unprognostic (2.01e-2)" "unprognostic (9.21e-2)" "unprognostic (3.05e-1)" "unprognostic (1.55e-1)" "unprognostic (2.53e-1)" "unprognostic (2.22e-2)" "unprognostic (3.01e-2)" "unprognostic (5.96e-2)" "unprognostic (5.87e-2)" "unprognostic (6.27e-2)" "unprognostic (6.06e-2)" "unprognostic (4.62e-1)" ATF5 ENSG00000169136 "Activating transcription factor 5" Q9Y2D1 19 49928702-49933935 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 21 "liver: 2375.4" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 1266.9" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 5 "Liver Hepatocellular Carcinoma (TCGA): 401.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 29.7" "Group enriched" "Detected in all" 7 "dendritic cells: 29.7;monocytes: 18.3" "Cancer enhanced" "Detected in all" "lymphoma: 577.1" "Adrenal gland - Adrenal cortex cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030187 Uncertain Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 55: Lymphoma - Immune response" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 13 Nucleoplasm "Vesicles, Cytosol" "HPA030187: " "unprognostic (1.12e-2)" "unprognostic (2.46e-2)" "unprognostic (3.36e-1)" "unprognostic (1.70e-1)" "unprognostic (2.44e-1)" "unprognostic (1.54e-2)" "unprognostic (4.89e-2)" "unprognostic (2.02e-3)" "unprognostic (1.20e-1)" "unprognostic (5.71e-3)" "potential prognostic unfavorable (9.91e-5)" "unprognostic (3.32e-3)" "unprognostic (7.52e-2)" "unprognostic (2.48e-1)" "unprognostic (5.12e-2)" "unprognostic (1.22e-1)" "unprognostic (1.20e-1)" "unprognostic (7.09e-2)" "unprognostic (1.30e-3)" "unprognostic (1.02e-1)" "unprognostic (1.23e-1)" "unprognostic (2.63e-1)" "unprognostic (2.40e-1)" "unprognostic (9.56e-3)" "unprognostic (1.72e-2)" "unprognostic (1.14e-1)" "unprognostic (2.32e-2)" "unprognostic (5.68e-2)" "unprognostic (8.85e-3)" "unprognostic (2.01e-1)" "unprognostic (1.72e-2)" ATF6 ATF6A ENSG00000118217 "Activating transcription factor 6" P18850 1 161766298-161977574 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation, Unfolded protein response" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 903.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005935, HPA071169" Approved Supported "Nucleoplasm,Nucleoli,Nucleoli fibrillar center,Endoplasmic reticulum,Golgi apparatus,Primary cilium,Primary cilium tip,Cytosol" NA NA 4800000 "Cluster 28: Neutrophils - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 45: Non-specific - Nuclear processes" "Cluster 24: Neutrophils - Innate immunity signal integration" 19 "Nucleoplasm, Golgi apparatus" "Nucleoli, Nucleoli fibrillar center, Endoplasmic reticulum, Primary cilium, Primary cilium tip, Cytosol" "HPA005935: , HPA071169: " "unprognostic (9.93e-2)" "unprognostic (1.18e-2)" "unprognostic (6.50e-3)" "unprognostic (1.27e-3)" "unprognostic (1.46e-1)" "unprognostic (9.01e-2)" "unprognostic (2.34e-2)" "unprognostic (2.72e-1)" "unprognostic (3.52e-3)" "unprognostic (6.34e-3)" "potential prognostic favorable (9.62e-5)" "unprognostic (2.07e-1)" "unprognostic (3.43e-2)" "unprognostic (1.07e-1)" "unprognostic (1.17e-1)" "unprognostic (3.62e-2)" "unprognostic (7.31e-3)" "unprognostic (7.07e-2)" "unprognostic (4.65e-1)" "unprognostic (1.34e-1)" "unprognostic (3.12e-3)" "unprognostic (3.36e-2)" "unprognostic (4.01e-1)" "unprognostic (1.09e-1)" "unprognostic (8.06e-2)" "unprognostic (9.14e-3)" "unprognostic (9.17e-2)" "unprognostic (1.43e-1)" "unprognostic (1.91e-1)" "unprognostic (3.92e-3)" "unprognostic (1.87e-1)" ATF6B "CREBL1, G13" ENSG00000213676 "Activating transcription factor 6 beta" Q99941 6 32115264-32128253 "Plasma proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation, Unfolded protein response" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 28.1;Bergmann glia: 36.8;Brain excitatory neurons: 26.0;Brain inhibitory neurons: 31.2;Choroid plexus epithelial cells: 17.7;Distal convoluted tubule cells: 31.1;Loop of henle epithelial cells: 27.4;Microglia: 21.6;Oligodendrocyte progenitor cells: 18.5;Oligodendrocytes: 17.9;Papillary tip epithelial cells: 29.7;Podocytes: 27.6;Proximal tubule cells: 28.2;Renal collecting duct intercalated cells: 21.3;Renal collecting duct principal cells: 34.2;Renal connecting tubule cells: 25.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046871 Uncertain Supported Nucleoplasm,Nucleoli NA NA 7300000 "Cluster 13: Non-specific - Mitochondria" "Cluster 64: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 28: Non-specific - Nuclear processes" "Cluster 98: Neurons - Neurotransmission & signaling" Nucleoplasm Nucleoli "HPA046871: " "unprognostic (4.14e-2)" "unprognostic (2.16e-1)" "unprognostic (5.05e-2)" "unprognostic (1.83e-3)" "unprognostic (2.49e-1)" "unprognostic (1.33e-1)" "unprognostic (5.35e-2)" "unprognostic (5.31e-2)" "unprognostic (3.66e-3)" "unprognostic (1.68e-1)" "unprognostic (5.07e-3)" "unprognostic (1.01e-1)" "unprognostic (1.12e-1)" "unprognostic (1.94e-2)" "unprognostic (1.02e-1)" "unprognostic (3.06e-2)" "unprognostic (4.95e-2)" "unprognostic (1.19e-1)" "unprognostic (4.56e-2)" "unprognostic (2.38e-1)" "unprognostic (1.80e-1)" "unprognostic (8.72e-3)" "unprognostic (8.07e-2)" "unprognostic (2.09e-1)" "unprognostic (1.01e-2)" "unprognostic (7.27e-2)" "unprognostic (2.42e-1)" "unprognostic (2.01e-2)" "unprognostic (1.46e-1)" "unprognostic (1.28e-2)" "unprognostic (2.42e-1)" ATF7 ATFA ENSG00000170653 "Activating transcription factor 7" P17544 12 53507856-53626410 "Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 148.1;Bergmann glia: 147.0;Brain excitatory neurons: 83.7;Brain inhibitory neurons: 38.6;Choroid plexus epithelial cells: 178.7;Ependymal cells: 106.4;Microglia: 103.1;Oligodendrocyte progenitor cells: 82.7;Oligodendrocytes: 205.6;Other brain neurons: 46.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003384 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 55: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 22: Non-specific - Basic cellular functions" 25 "Nucleoplasm, Cytosol" "HPA003384: " "unprognostic (2.41e-1)" "unprognostic (1.22e-2)" "unprognostic (1.33e-1)" "unprognostic (2.02e-2)" "unprognostic (1.80e-1)" "unprognostic (1.39e-2)" "unprognostic (3.44e-1)" "unprognostic (2.60e-1)" "unprognostic (1.67e-1)" "potential prognostic unfavorable (9.51e-5)" "validated prognostic favorable (2.80e-5)" "validated prognostic favorable (2.45e-4)" "unprognostic (1.11e-1)" "unprognostic (4.37e-2)" "unprognostic (2.44e-1)" "unprognostic (3.20e-1)" "unprognostic (3.74e-2)" "unprognostic (4.32e-2)" "unprognostic (2.92e-1)" "unprognostic (3.15e-1)" "unprognostic (2.11e-2)" "unprognostic (3.48e-3)" "unprognostic (8.66e-2)" "unprognostic (4.83e-2)" "unprognostic (5.08e-2)" "unprognostic (4.00e-2)" "unprognostic (1.12e-2)" "unprognostic (2.72e-3)" "unprognostic (2.72e-1)" "unprognostic (5.61e-2)" "unprognostic (1.17e-1)" ATF7-NPFF ENSG00000267281 "ATF7-NPFF readthrough" 12 53506691-53625979 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Epididymal principal cells: 3.6;Late spermatids: 2.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA003384 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 16: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" "Nucleoplasm, Cytosol" "HPA003384: " "unprognostic (9.30e-2)" ATF7IP "ATF7IP1, FLJ10688, p621" ENSG00000171681 "Activating transcription factor 7 interacting protein" Q6VMQ6 12 14365676-14502931 "Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Activator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "B-cells: 577.9;Neutrophil progenitors: 517.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016578, HPA023505" Supported Enhanced "Nucleoplasm,Nuclear bodies" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 17 "Nucleoplasm, Nuclear bodies" "HPA016578: , HPA023505: " "unprognostic (2.09e-2)" "unprognostic (1.20e-2)" "unprognostic (1.59e-1)" "unprognostic (2.12e-1)" "unprognostic (7.20e-2)" "unprognostic (6.87e-3)" "unprognostic (1.23e-2)" "potential prognostic favorable (1.01e-4)" "unprognostic (3.01e-2)" "unprognostic (5.71e-3)" "unprognostic (2.17e-3)" "unprognostic (1.11e-2)" "unprognostic (1.18e-1)" "unprognostic (8.46e-2)" "unprognostic (2.59e-2)" "unprognostic (1.41e-1)" "unprognostic (1.28e-2)" "unprognostic (1.82e-1)" "unprognostic (1.50e-1)" "unprognostic (3.10e-1)" "unprognostic (3.04e-2)" "unprognostic (7.58e-2)" "potential prognostic unfavorable (3.50e-4)" "unprognostic (3.05e-1)" "unprognostic (1.39e-1)" "unprognostic (1.67e-2)" "unprognostic (1.50e-1)" "unprognostic (4.53e-2)" "unprognostic (7.50e-2)" "unprognostic (1.55e-1)" "unprognostic (1.95e-1)" ATF7IP2 FLJ12668 ENSG00000166669 "Activating transcription factor 7 interacting protein 2" Q5U623 16 10326434-10483638 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 16.7" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 601.2;Parietal cells: 468.5;Sertoli cells: 1021.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Sertoli cells" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebral cortex: 4.4" "HPA041156, HPA041228" Enhanced NA NA "Cluster 27: T-cells - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 51: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 6 "HPA041156: , HPA041228: " "unprognostic (1.45e-1)" "unprognostic (6.21e-2)" "unprognostic (1.89e-1)" "unprognostic (1.43e-1)" "unprognostic (1.23e-1)" "unprognostic (3.16e-1)" "unprognostic (3.87e-1)" "unprognostic (8.95e-2)" "unprognostic (1.21e-2)" "unprognostic (4.32e-3)" "unprognostic (1.82e-1)" "unprognostic (2.39e-2)" "unprognostic (9.50e-2)" "unprognostic (9.24e-2)" "unprognostic (2.21e-3)" "unprognostic (2.10e-1)" "unprognostic (2.20e-3)" "unprognostic (2.32e-1)" "unprognostic (4.06e-2)" "unprognostic (1.34e-1)" "unprognostic (1.66e-1)" "unprognostic (3.76e-1)" "potential prognostic favorable (8.64e-5)" "unprognostic (1.04e-1)" "unprognostic (1.66e-2)" "unprognostic (9.42e-2)" "unprognostic (3.16e-1)" "unprognostic (5.03e-2)" "unprognostic (2.16e-1)" ATG10 "APG10L, DKFZP586I0418, FLJ13954" ENSG00000152348 "Autophagy related 10" Q9H0Y0 5 81972023-82276857 "Predicted intracellular proteins" "Autophagy, Protein transport, Transport, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Thymocytes: 431.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044163 Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 61: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 9: T-cells - Adaptive immunity: Regulation" 15 Nucleoli Nucleoplasm "HPA044163: " "unprognostic (2.56e-1)" "unprognostic (3.36e-1)" "unprognostic (3.70e-2)" "unprognostic (4.66e-1)" "unprognostic (3.17e-1)" "unprognostic (1.94e-2)" "unprognostic (1.76e-2)" "unprognostic (8.65e-2)" "unprognostic (2.79e-1)" "potential prognostic unfavorable (3.34e-5)" "unprognostic (3.44e-3)" "unprognostic (2.88e-2)" "unprognostic (1.35e-1)" "unprognostic (1.07e-3)" "potential prognostic unfavorable (8.12e-4)" "unprognostic (6.75e-3)" "unprognostic (3.03e-2)" "unprognostic (7.04e-2)" "unprognostic (6.02e-3)" "unprognostic (2.24e-2)" "unprognostic (2.30e-2)" "unprognostic (7.82e-2)" "unprognostic (5.51e-3)" "unprognostic (3.85e-1)" "unprognostic (4.40e-3)" "unprognostic (3.13e-1)" "unprognostic (5.48e-2)" "unprognostic (5.62e-2)" "unprognostic (2.12e-1)" "unprognostic (2.43e-1)" "unprognostic (8.93e-2)" ATG101 "C12orf44, FLJ11773" ENSG00000123395 "Autophagy related 101" Q9BSB4 12 52069246-52077495 "Predicted intracellular proteins, Transporters" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 198.2;Esophageal apical cells: 143.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "plasmacytoid DC: 261.9" "Lineage enriched" "Detected in all" 6 "dendritic cells: 261.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039904 Approved NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 12: Non-specific - Vasculature" "Cluster 38: Non-specific - Transcription" "Cluster 26: Keratinocytes - Keratinization" 39 "HPA039904: " "unprognostic (3.84e-2)" "unprognostic (1.10e-2)" "unprognostic (1.00e-1)" "unprognostic (6.53e-2)" "unprognostic (1.85e-2)" "unprognostic (9.29e-2)" "unprognostic (9.54e-3)" "unprognostic (2.22e-3)" "unprognostic (9.69e-2)" "unprognostic (3.21e-2)" "unprognostic (4.65e-2)" "unprognostic (2.15e-1)" "potential prognostic unfavorable (1.78e-7)" "unprognostic (2.56e-2)" "unprognostic (3.38e-2)" "unprognostic (5.22e-2)" "unprognostic (6.15e-2)" "unprognostic (1.33e-1)" "unprognostic (2.25e-1)" "unprognostic (2.42e-1)" "unprognostic (2.13e-1)" "unprognostic (9.83e-2)" "unprognostic (2.06e-1)" "unprognostic (1.25e-1)" "unprognostic (1.13e-1)" "unprognostic (1.72e-1)" "unprognostic (2.52e-1)" "unprognostic (1.06e-1)" "unprognostic (7.28e-2)" ATG12 "APG12, APG12L" ENSG00000145782 "Autophagy related 12" O94817 5 115828200-115841837 "Predicted intracellular proteins, Transporters" "Autophagy, Host-virus interaction, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013272, HPA068989" Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 24: Non-specific - Transcription" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 7: Non-specific - Transcription" 42 "Nucleoplasm, Vesicles" "CAB013272: , HPA068989: " "unprognostic (8.64e-2)" "unprognostic (2.23e-3)" "unprognostic (2.96e-1)" "unprognostic (1.61e-1)" "unprognostic (6.95e-2)" "unprognostic (1.86e-2)" "unprognostic (1.57e-1)" "unprognostic (6.40e-2)" "unprognostic (1.13e-2)" "potential prognostic unfavorable (7.17e-4)" "unprognostic (1.27e-2)" "unprognostic (3.16e-2)" "unprognostic (2.03e-2)" "potential prognostic unfavorable (1.56e-5)" "unprognostic (1.62e-1)" "unprognostic (4.59e-3)" "unprognostic (3.89e-2)" "unprognostic (5.19e-2)" "unprognostic (1.54e-1)" "unprognostic (9.32e-2)" "potential prognostic unfavorable (4.37e-4)" "unprognostic (7.56e-2)" "potential prognostic unfavorable (1.61e-4)" "unprognostic (1.29e-1)" "unprognostic (6.46e-2)" "unprognostic (8.43e-3)" "unprognostic (2.34e-2)" "unprognostic (1.86e-1)" "unprognostic (2.00e-1)" "potential prognostic unfavorable (1.81e-4)" "unprognostic (2.34e-1)" ATG13 KIAA0652 ENSG00000175224 "Autophagy related 13" O75143 11 46617527-46674818 "Cancer-related genes, Predicted intracellular proteins, Transporters" Autophagy "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial glandular cells: 186.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039350 Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 67: Testis - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 24: Non-specific - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 172 Cytosol "Nucleoplasm, Plasma membrane" "HPA039350: " "unprognostic (1.63e-1)" "unprognostic (1.10e-1)" "unprognostic (1.18e-2)" "unprognostic (3.41e-2)" "unprognostic (1.87e-1)" "unprognostic (7.52e-2)" "unprognostic (1.53e-2)" "unprognostic (2.30e-1)" "unprognostic (4.73e-2)" "unprognostic (1.44e-2)" "unprognostic (1.51e-1)" "unprognostic (1.08e-1)" "potential prognostic unfavorable (4.59e-6)" "unprognostic (1.32e-2)" "unprognostic (8.42e-2)" "unprognostic (2.39e-2)" "unprognostic (1.72e-1)" "unprognostic (9.61e-2)" "unprognostic (2.42e-2)" "unprognostic (1.73e-2)" "unprognostic (3.00e-1)" "unprognostic (9.33e-2)" "unprognostic (6.25e-2)" "unprognostic (1.41e-2)" "unprognostic (6.40e-2)" "unprognostic (1.71e-1)" "unprognostic (3.76e-1)" "unprognostic (2.22e-1)" "unprognostic (1.62e-1)" "unprognostic (1.46e-1)" ATG14 "ATG14L, KIAA0831" ENSG00000126775 "Autophagy related 14" Q6ZNE5 14 55366391-55411830 "Predicted intracellular proteins, Transporters" Autophagy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Myonuclei: 187.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037242, CAB080659" Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 49 "Vesicles, Plasma membrane" "CAB037242: , CAB080659: " "unprognostic (2.75e-2)" "unprognostic (5.11e-2)" "potential prognostic favorable (2.55e-4)" "unprognostic (4.49e-2)" "potential prognostic unfavorable (2.71e-4)" "unprognostic (4.24e-3)" "unprognostic (1.82e-2)" "unprognostic (5.80e-2)" "potential prognostic unfavorable (2.48e-4)" "validated prognostic favorable (1.70e-8)" "validated prognostic favorable (6.98e-4)" "unprognostic (1.25e-1)" "potential prognostic unfavorable (9.74e-4)" "unprognostic (3.00e-1)" "unprognostic (2.37e-2)" "unprognostic (1.48e-1)" "unprognostic (1.35e-1)" "unprognostic (4.23e-1)" "unprognostic (1.61e-1)" "potential prognostic unfavorable (6.35e-4)" "unprognostic (2.06e-2)" "unprognostic (1.83e-2)" "unprognostic (3.39e-2)" "unprognostic (1.67e-1)" "unprognostic (1.20e-1)" "unprognostic (1.06e-1)" "unprognostic (4.08e-1)" "unprognostic (5.17e-1)" "unprognostic (3.98e-2)" "unprognostic (1.06e-1)" ATG16L1 "APG16L, ATG16A, ATG16L, FLJ10035, WDR30" ENSG00000085978 "Autophagy related 16 like 1" Q676U5 2 233210051-233295674 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Autophagy, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Choroid plexus epithelial cells: 169.7" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 135.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells, Minor Salivary Gland - Smooth muscle cells, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012577, HPA063900" Supported Supported "Cytosol,Equatorial segment,Mid piece,Principal piece" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 106 Cytosol "Equatorial segment, Mid piece, Principal piece" "HPA012577: , HPA063900: " "unprognostic (3.71e-2)" "unprognostic (4.94e-2)" "unprognostic (4.18e-2)" "unprognostic (2.08e-3)" "unprognostic (2.90e-1)" "unprognostic (1.09e-1)" "unprognostic (2.55e-1)" "unprognostic (4.36e-2)" "unprognostic (2.09e-2)" "unprognostic (6.59e-2)" "unprognostic (3.08e-2)" "unprognostic (9.14e-2)" "unprognostic (5.62e-2)" "potential prognostic unfavorable (3.91e-4)" "unprognostic (2.81e-3)" "unprognostic (2.34e-3)" "unprognostic (6.25e-3)" "unprognostic (1.34e-1)" "unprognostic (4.51e-2)" "unprognostic (9.93e-3)" "unprognostic (2.94e-1)" "potential prognostic unfavorable (7.33e-4)" "unprognostic (3.44e-2)" "unprognostic (5.96e-2)" "unprognostic (3.86e-2)" "unprognostic (1.86e-1)" "unprognostic (3.41e-2)" "unprognostic (8.98e-2)" "unprognostic (1.54e-1)" "unprognostic (1.82e-1)" "unprognostic (2.23e-1)" ATG16L2 "ATG16B, FLJ00012, WDR80" ENSG00000168010 "Autophagy related 16 like 2" Q8NAA4 11 72814406-72843674 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 129.3;lymphoid tissue: 128.5" "Cell type enriched" "Detected in many" 4 "Neutrophils: 604.0" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 135.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 45.5;neutrophil: 59.8" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Leukemia: 45.9" "Breast - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045444, HPA050312" Approved Enhanced Nucleoplasm NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 5 Nucleoplasm "HPA045444: , HPA050312: " "unprognostic (4.34e-3)" "unprognostic (7.76e-3)" "unprognostic (1.76e-1)" "unprognostic (2.37e-1)" "unprognostic (2.67e-1)" "unprognostic (2.05e-2)" "unprognostic (5.45e-2)" "unprognostic (1.21e-2)" "unprognostic (3.05e-3)" "unprognostic (5.41e-2)" "potential prognostic unfavorable (7.45e-4)" "unprognostic (1.21e-1)" "unprognostic (2.85e-3)" "unprognostic (1.56e-1)" "unprognostic (2.40e-2)" "unprognostic (1.82e-2)" "unprognostic (3.20e-1)" "unprognostic (1.23e-1)" "unprognostic (1.29e-1)" "unprognostic (5.66e-2)" "potential prognostic favorable (1.90e-4)" "unprognostic (4.91e-3)" "unprognostic (6.16e-3)" "unprognostic (1.39e-1)" "unprognostic (1.40e-1)" "unprognostic (1.31e-2)" "unprognostic (2.65e-1)" "unprognostic (1.15e-1)" "unprognostic (4.46e-2)" "unprognostic (2.43e-1)" "unprognostic (1.27e-1)" ATG2A "BLTP4A, KIAA0404" ENSG00000110046 "Autophagy related 2A" Q2TAZ0 11 64894546-64917211 "Predicted intracellular proteins, Transporters" "Autophagy, Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 362.1;Syncytiotrophoblasts: 95.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 17.0" "Lineage enriched" "Detected in many" 7 "granulocytes: 17.0" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038715 Uncertain Uncertain Nucleoplasm,Vesicles NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 12: Non-specific - Vasculature" "Cluster 24: Non-specific - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 9 Vesicles Nucleoplasm "HPA038715: " "unprognostic (3.49e-1)" "unprognostic (1.78e-1)" "potential prognostic favorable (2.03e-4)" "unprognostic (4.81e-2)" "unprognostic (3.33e-2)" "unprognostic (5.82e-2)" "unprognostic (4.93e-2)" "unprognostic (2.44e-1)" "unprognostic (1.16e-1)" "unprognostic (4.73e-2)" "unprognostic (7.42e-2)" "unprognostic (2.64e-1)" "unprognostic (4.98e-2)" "unprognostic (9.28e-3)" "unprognostic (2.58e-1)" "unprognostic (7.26e-2)" "unprognostic (7.34e-2)" "unprognostic (2.86e-1)" "unprognostic (3.56e-2)" "unprognostic (6.06e-2)" "unprognostic (4.79e-1)" "unprognostic (5.63e-2)" "unprognostic (2.08e-1)" "unprognostic (8.65e-2)" "unprognostic (2.54e-2)" "potential prognostic favorable (3.03e-5)" "unprognostic (2.03e-1)" "unprognostic (4.81e-2)" "unprognostic (5.69e-2)" "unprognostic (2.00e-1)" "unprognostic (6.16e-2)" ATG2B "BLTP4B, C14orf103, FLJ10242" ENSG00000066739 "Autophagy related 2B" Q96BY7 14 96279195-96363341 "Predicted intracellular proteins, Transporters" "Autophagy, Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001427, HPA005734, HPA019665" Approved Supported "Endoplasmic reticulum,Vesicles" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 7: Non-specific - Transcription" 6 "Endoplasmic reticulum, Vesicles" "HPA001427: , HPA005734: , HPA019665: " "unprognostic (2.32e-1)" "unprognostic (6.39e-2)" "unprognostic (1.96e-1)" "unprognostic (3.29e-1)" "unprognostic (2.57e-1)" "unprognostic (4.22e-3)" "unprognostic (1.64e-1)" "unprognostic (2.88e-2)" "unprognostic (6.42e-2)" "unprognostic (2.35e-1)" "validated prognostic favorable (2.43e-4)" "validated prognostic favorable (6.91e-4)" "unprognostic (2.88e-2)" "unprognostic (4.03e-1)" "unprognostic (6.42e-3)" "unprognostic (3.68e-2)" "unprognostic (1.18e-1)" "unprognostic (2.83e-1)" "unprognostic (1.62e-1)" "unprognostic (3.56e-1)" "unprognostic (1.22e-2)" "unprognostic (5.92e-3)" "unprognostic (4.25e-2)" "unprognostic (1.31e-1)" "unprognostic (7.58e-2)" "unprognostic (3.35e-1)" "unprognostic (4.14e-2)" "unprognostic (9.78e-2)" "unprognostic (3.70e-1)" "unprognostic (4.35e-2)" "unprognostic (2.49e-1)" ATG3 "APG3L, DKFZp564M1178, FLJ22125, MGC15201, PC3-96" ENSG00000144848 "Autophagy related 3" Q9NT62 3 112532510-112562046 "Predicted intracellular proteins, Transporters" "Autophagy, Protein transport, Transport, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 767.9;Late primary spermatocytes: 649.2;Neutrophils: 385.0;Oocytes: 327.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037260, HPA040471" Enhanced Supported "Plasma membrane,Cytosol" NA NA 90000 "Cluster 40: Monocytes - Innate immune response" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 35 "Plasma membrane, Cytosol" "CAB037260: , HPA040471: " "unprognostic (3.04e-1)" "unprognostic (1.35e-2)" "unprognostic (1.20e-2)" "unprognostic (5.78e-2)" "unprognostic (7.37e-2)" "unprognostic (2.64e-1)" "unprognostic (3.64e-1)" "unprognostic (1.06e-1)" "unprognostic (1.45e-1)" "unprognostic (4.34e-2)" "potential prognostic favorable (7.50e-6)" "unprognostic (1.42e-1)" "unprognostic (4.73e-2)" "potential prognostic unfavorable (3.90e-8)" "unprognostic (7.38e-3)" "unprognostic (2.98e-2)" "unprognostic (7.74e-3)" "unprognostic (1.17e-1)" "unprognostic (1.85e-1)" "unprognostic (7.73e-2)" "unprognostic (2.32e-1)" "unprognostic (1.78e-3)" "unprognostic (1.41e-2)" "unprognostic (3.17e-2)" "unprognostic (3.65e-2)" "unprognostic (4.48e-2)" "unprognostic (1.56e-1)" "unprognostic (5.17e-2)" "unprognostic (1.11e-1)" "unprognostic (9.91e-2)" "unprognostic (2.05e-1)" ATG4A "APG4A, AUTL2" ENSG00000101844 "Autophagy related 4A cysteine peptidase" Q8WYN0 X 108091668-108154671 "Enzymes, Predicted intracellular proteins" "Autophagy, Lipid metabolism, Protein transport, Transport, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 71.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Chief cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036374, HPA064759" Uncertain Approved "Actin filaments,Microtubules" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 6 Microtubules "Actin filaments" "HPA036374: , HPA064759: " "unprognostic (8.23e-2)" "potential prognostic unfavorable (5.50e-6)" "unprognostic (3.43e-2)" "unprognostic (5.09e-2)" "unprognostic (1.74e-3)" "unprognostic (1.73e-1)" "unprognostic (2.42e-1)" "unprognostic (4.59e-1)" "unprognostic (1.53e-1)" "potential prognostic unfavorable (9.21e-4)" "validated prognostic favorable (9.32e-9)" "validated prognostic favorable (3.87e-4)" "unprognostic (1.24e-1)" "unprognostic (4.60e-1)" "unprognostic (2.32e-1)" "unprognostic (6.75e-2)" "unprognostic (5.05e-2)" "unprognostic (6.94e-2)" "unprognostic (8.31e-2)" "unprognostic (4.55e-1)" "unprognostic (8.38e-2)" "unprognostic (4.68e-2)" "unprognostic (3.52e-1)" "unprognostic (9.31e-2)" "unprognostic (2.44e-1)" "unprognostic (1.69e-3)" "unprognostic (2.42e-1)" "unprognostic (2.04e-1)" "unprognostic (1.71e-1)" "unprognostic (4.50e-3)" "potential prognostic unfavorable (7.00e-4)" ATG4B "APG4B, AUTL1, DKFZp586D1822, KIAA0943" ENSG00000168397 "Autophagy related 4B cysteine peptidase" Q9Y4P1 2 241637213-241673857 "Enzymes, Predicted intracellular proteins, Transporters" "Autophagy, Protein transport, Transport, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037195, HPA069803" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 64: Non-specific - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 77 "Nucleoplasm, Cytosol" "CAB037195: , HPA069803: " "unprognostic (1.77e-1)" "unprognostic (6.17e-2)" "unprognostic (6.24e-2)" "unprognostic (6.76e-2)" "unprognostic (1.24e-1)" "unprognostic (2.34e-3)" "unprognostic (1.07e-1)" "unprognostic (1.63e-1)" "unprognostic (3.19e-3)" "unprognostic (5.08e-2)" "unprognostic (1.26e-2)" "unprognostic (3.02e-1)" "unprognostic (6.00e-3)" "potential prognostic unfavorable (1.69e-6)" "unprognostic (1.53e-2)" "unprognostic (1.71e-1)" "unprognostic (2.78e-1)" "unprognostic (1.98e-1)" "unprognostic (2.65e-2)" "unprognostic (1.76e-1)" "unprognostic (4.47e-3)" "unprognostic (1.13e-3)" "potential prognostic unfavorable (2.45e-5)" "unprognostic (6.84e-3)" "unprognostic (1.80e-1)" "unprognostic (5.10e-3)" "unprognostic (7.89e-2)" "unprognostic (1.27e-2)" "unprognostic (1.16e-1)" "unprognostic (6.07e-2)" "unprognostic (1.09e-1)" ATG4C "APG4C, AUTL1, AUTL3, FLJ14867" ENSG00000125703 "Autophagy related 4C cysteine peptidase" Q96DT6 1 62784132-62865516 "Enzymes, Predicted intracellular proteins" "Autophagy, Protein transport, Transport, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglia: 176.6;Oligodendrocytes: 481.7;Retinal pigment epithelial cells: 302.7" "Cell type enhanced" "Detected in all" "oligodendrocyte: 630.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007049 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 32: Basophils - Transcription" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 5: Rhabdoid - Unknown function" "Cluster 80: Oligodendrocytes - Myelination" 1 "Nucleoplasm, Cytosol" "HPA007049: " "unprognostic (1.81e-1)" "unprognostic (3.71e-1)" "unprognostic (1.16e-1)" "unprognostic (4.01e-2)" "unprognostic (2.74e-2)" "unprognostic (1.82e-1)" "unprognostic (2.60e-1)" "unprognostic (2.20e-2)" "unprognostic (2.18e-1)" "unprognostic (1.67e-3)" "potential prognostic favorable (4.18e-7)" "unprognostic (4.47e-3)" "unprognostic (4.18e-2)" "unprognostic (1.26e-3)" "unprognostic (3.01e-1)" "unprognostic (3.98e-1)" "unprognostic (9.60e-2)" "unprognostic (2.46e-1)" "unprognostic (1.75e-2)" "unprognostic (1.48e-2)" "unprognostic (9.19e-3)" "unprognostic (1.20e-1)" "unprognostic (3.77e-2)" "unprognostic (9.57e-2)" "unprognostic (6.91e-2)" "unprognostic (1.05e-1)" "unprognostic (7.40e-3)" "unprognostic (1.29e-1)" "unprognostic (1.13e-2)" "unprognostic (8.45e-3)" "unprognostic (1.08e-1)" ATG4D "APG4-D, APG4D, AUTL4" ENSG00000130734 "Autophagy related 4D cysteine peptidase" Q86TL0 19 10543895-10553418 "Enzymes, Predicted intracellular proteins, Transporters" "Apoptosis, Autophagy, Protein transport, Transport, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 103.2;Enterocytes: 112.9;Esophageal apical cells: 90.4;Late primary spermatocytes: 211.4;Megakaryocytes: 136.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA067683 Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 15: Non-specific - Transcription" "Cluster 23: Non-specific - Transcription" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" "Nucleoplasm, Mitochondria" "HPA067683: " "unprognostic (5.23e-2)" "unprognostic (1.86e-1)" "unprognostic (3.54e-1)" "unprognostic (6.27e-2)" "unprognostic (6.46e-3)" "unprognostic (7.62e-3)" "unprognostic (1.79e-1)" "unprognostic (6.48e-2)" "unprognostic (3.81e-3)" "unprognostic (1.14e-2)" "unprognostic (6.45e-3)" "unprognostic (8.09e-2)" "unprognostic (3.06e-3)" "unprognostic (9.22e-3)" "unprognostic (4.55e-2)" "unprognostic (1.18e-2)" "unprognostic (4.41e-1)" "unprognostic (5.58e-2)" "unprognostic (8.26e-2)" "unprognostic (9.39e-2)" "unprognostic (6.66e-2)" "unprognostic (1.49e-2)" "unprognostic (1.94e-2)" "unprognostic (9.86e-2)" "unprognostic (1.65e-1)" "unprognostic (9.51e-2)" "unprognostic (1.30e-1)" "unprognostic (2.43e-3)" "unprognostic (1.41e-1)" "unprognostic (6.36e-2)" "unprognostic (8.89e-2)" ATG5 "APG5, APG5L, ASP, hAPG5" ENSG00000057663 "Autophagy related 5" Q9H1Y0 6 106045423-106325791 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Apoptosis, Autophagy, Host-virus interaction, Immunity" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 655.3;Plasma cells: 441.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034432, CAB037309, HPA042973" Approved Approved "Vesicles,Primary cilium transition zone,Centrosome,Basal body" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 23: Choroid plexus - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 67: Plasma cells - Plasma cell differentiation" 73 "Primary cilium transition zone, Centrosome, Basal body" Vesicles "CAB034432: , CAB037309: , HPA042973: " "unprognostic (2.84e-1)" "potential prognostic unfavorable (3.13e-4)" "unprognostic (1.52e-2)" "unprognostic (6.36e-2)" "unprognostic (2.78e-1)" "unprognostic (1.08e-2)" "unprognostic (8.42e-3)" "unprognostic (1.53e-1)" "potential prognostic unfavorable (4.26e-4)" "unprognostic (4.57e-2)" "unprognostic (3.04e-2)" "unprognostic (6.86e-2)" "unprognostic (2.86e-1)" "unprognostic (4.69e-2)" "unprognostic (1.93e-3)" "unprognostic (5.07e-2)" "unprognostic (2.66e-1)" "unprognostic (1.64e-1)" "unprognostic (2.25e-1)" "unprognostic (9.50e-2)" "unprognostic (1.20e-2)" "unprognostic (3.34e-2)" "unprognostic (2.72e-3)" "unprognostic (5.23e-2)" "unprognostic (1.44e-1)" "unprognostic (7.89e-2)" "unprognostic (2.53e-1)" "unprognostic (1.24e-1)" "unprognostic (2.81e-1)" "unprognostic (2.36e-1)" "unprognostic (2.68e-2)" ATG7 "APG7L, DKFZp434N0735, GSA7" ENSG00000197548 "Autophagy related 7" O95352 3 11272309-11557665 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Autophagy, Biological rhythms, Protein transport, Transport, Ubl conjugation pathway" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 1324.4;Neutrophils: 1938.6;Oocytes: 1418.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Macrophages, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007639, CAB018771" Supported Approved "Nucleoplasm,Plasma membrane,Cytosol,Connecting piece,Flagellar centriole,Mid piece" NA NA 42000 "Cluster 7: Non-specific - Innate immune response" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 36 Cytosol "Nucleoplasm, Plasma membrane, Connecting piece, Flagellar centriole, Mid piece" "CAB018771: , HPA007639: " "unprognostic (4.89e-2)" "unprognostic (5.58e-3)" "unprognostic (9.63e-2)" "unprognostic (1.79e-1)" "unprognostic (1.55e-1)" "unprognostic (8.73e-2)" "unprognostic (1.48e-1)" "unprognostic (1.25e-1)" "unprognostic (1.51e-1)" "potential prognostic unfavorable (5.02e-5)" "potential prognostic favorable (1.50e-5)" "unprognostic (2.27e-1)" "unprognostic (1.32e-2)" "potential prognostic unfavorable (1.53e-5)" "unprognostic (1.21e-2)" "unprognostic (5.41e-2)" "unprognostic (2.04e-2)" "unprognostic (2.36e-1)" "unprognostic (1.27e-1)" "potential prognostic unfavorable (2.14e-4)" "unprognostic (2.50e-3)" "unprognostic (1.89e-3)" "unprognostic (6.54e-2)" "unprognostic (1.02e-1)" "unprognostic (6.55e-3)" "unprognostic (2.47e-3)" "unprognostic (3.83e-1)" "unprognostic (1.02e-1)" "unprognostic (1.84e-1)" "unprognostic (8.85e-2)" "unprognostic (4.87e-2)" ATG9A "APG9L1, FLJ22169" ENSG00000198925 "Autophagy related 9A" Q7Z3C6 2 219219380-219229717 "Predicted membrane proteins, Transporters" "Autophagy, Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 136.4" "Cell type enhanced" "Detected in many" "Astrocytes: 16.3;Bergmann glia: 12.6;Brain excitatory neurons: 17.8;Brain inhibitory neurons: 18.0;Oligodendrocyte progenitor cells: 17.6;Oligodendrocytes: 18.4;Other brain neurons: 16.2;Tuft cells: 46.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059551 Uncertain Supported Vesicles NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 22: Non-specific - Basic cellular functions" 52 Vesicles "HPA059551: " "unprognostic (5.99e-2)" "unprognostic (5.77e-3)" "unprognostic (1.69e-1)" "unprognostic (4.22e-2)" "unprognostic (1.10e-1)" "unprognostic (2.41e-2)" "unprognostic (2.51e-1)" "unprognostic (4.59e-1)" "unprognostic (8.71e-2)" "unprognostic (1.39e-1)" "unprognostic (1.42e-3)" "unprognostic (3.99e-2)" "unprognostic (9.30e-2)" "potential prognostic unfavorable (9.22e-4)" "unprognostic (1.72e-3)" "unprognostic (3.71e-3)" "unprognostic (4.60e-3)" "unprognostic (1.57e-1)" "unprognostic (1.52e-1)" "unprognostic (1.17e-3)" "unprognostic (2.58e-1)" "unprognostic (2.61e-1)" "unprognostic (3.51e-1)" "unprognostic (3.09e-1)" "unprognostic (5.53e-2)" "unprognostic (4.97e-3)" "unprognostic (4.53e-1)" "unprognostic (2.62e-2)" "unprognostic (1.96e-2)" "unprognostic (2.72e-1)" "unprognostic (3.44e-1)" ATG9B "APG9L2, FLJ14885, NOS3AS, SONE" ENSG00000181652 "Autophagy related 9B" Q674R7 7 151012209-151024499 "Metabolic proteins, Predicted membrane proteins, Transporters" "Autophagy, Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 9.9;pituitary gland: 5.9;testis: 6.9" "Group enriched" "Detected in many" 4 "Esophageal apical cells: 312.4;Syncytiotrophoblasts: 393.3" "Cell type enhanced" "Detected in many" "ependymal cell: 32.8" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 6.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adrenal gland - Adrenal medulla cells, Liver - Vascular endothelial cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 3 "unprognostic (1.05e-1)" "unprognostic (6.16e-2)" "unprognostic (5.02e-2)" "unprognostic (3.42e-2)" "unprognostic (1.13e-3)" "unprognostic (2.11e-3)" "unprognostic (3.82e-2)" "unprognostic (1.76e-1)" "unprognostic (1.13e-2)" "potential prognostic favorable (1.01e-5)" "unprognostic (1.52e-1)" "unprognostic (1.06e-1)" ATIC "AICARFT, IMPCHASE, PURH" ENSG00000138363 "5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase" P31939 2 215311956-215349773 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Purine biosynthesis" "Hydrolase, Multifunctional enzyme, Transferase" "Cancer-related genes, Disease variant, Epilepsy, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 213.6;Extravillous trophoblasts: 198.7;Migrating cytotrophoblasts: 238.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013462, HPA021012" Supported Approved "Plasma membrane,Cytosol" NA NA 4900000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 8 Cytosol "Plasma membrane" "CAB013462: , HPA021012: " "unprognostic (1.03e-1)" "unprognostic (2.48e-3)" "unprognostic (1.03e-2)" "unprognostic (2.29e-1)" "unprognostic (1.05e-1)" "unprognostic (1.68e-1)" "unprognostic (1.25e-1)" "unprognostic (3.71e-2)" "unprognostic (2.21e-2)" "unprognostic (1.45e-1)" "unprognostic (7.94e-3)" "unprognostic (1.53e-1)" "unprognostic (1.48e-3)" "validated prognostic unfavorable (1.07e-8)" "validated prognostic unfavorable (1.55e-8)" "potential prognostic unfavorable (2.86e-4)" "unprognostic (2.74e-3)" "unprognostic (2.35e-1)" "unprognostic (3.67e-1)" "unprognostic (9.19e-2)" "unprognostic (7.04e-2)" "unprognostic (2.95e-3)" "unprognostic (1.32e-1)" "unprognostic (2.09e-3)" "unprognostic (6.19e-3)" "unprognostic (4.06e-2)" "unprognostic (2.84e-2)" "unprognostic (5.04e-2)" "unprognostic (3.82e-1)" "unprognostic (1.74e-2)" "unprognostic (2.80e-1)" ATL1 "AD-FSP, FSP1, SPG3, SPG3A" ENSG00000198513 "Atlastin GTPase 1" Q8WXF7 14 50532509-50634017 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Hydrolase "Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 56.1" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 159.9;Brain inhibitory neurons: 152.0;Breast lactating cells: 152.3;Oligodendrocyte progenitor cells: 133.2;Oligodendrocytes: 196.1;Other brain neurons: 171.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 12.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 12.9" "Cancer enhanced" "Detected in many" "Neuroblastoma: 12.6" "Kidney - Fibroblasts, Testis - Early spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027550 Enhanced NA NA 19000 "Cluster 46: Basophils - Proteolysis" "Cluster 73: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 28 "HPA027550: " "unprognostic (4.34e-2)" "unprognostic (3.12e-2)" "unprognostic (5.56e-1)" "unprognostic (6.40e-2)" "unprognostic (1.71e-1)" "unprognostic (1.65e-1)" "unprognostic (1.79e-1)" "potential prognostic favorable (7.50e-4)" "unprognostic (1.42e-1)" "unprognostic (7.83e-2)" "validated prognostic favorable (2.15e-7)" "validated prognostic favorable (2.96e-5)" "potential prognostic favorable (1.76e-4)" "unprognostic (8.30e-3)" "unprognostic (1.32e-1)" "unprognostic (7.80e-2)" "unprognostic (1.45e-1)" "unprognostic (1.49e-1)" "unprognostic (2.69e-2)" "unprognostic (2.36e-2)" "unprognostic (5.94e-2)" "unprognostic (3.26e-1)" "unprognostic (7.56e-2)" "unprognostic (8.04e-3)" "unprognostic (2.19e-1)" "unprognostic (1.12e-1)" "unprognostic (5.00e-2)" "unprognostic (1.25e-1)" "unprognostic (1.08e-1)" "unprognostic (7.47e-2)" ATL2 "ARL6IP2, atlastin2" ENSG00000119787 "Atlastin GTPase 2" Q8NHH9 2 38293954-38377285 "Essential proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Lacrimal acinar cells: 321.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029108, HPA075302" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" 25 "Endoplasmic reticulum" "HPA029108: , HPA075302: " "unprognostic (1.02e-1)" "unprognostic (5.91e-2)" "unprognostic (2.92e-1)" "unprognostic (6.25e-3)" "unprognostic (2.15e-2)" "unprognostic (7.11e-2)" "unprognostic (2.84e-1)" "unprognostic (1.34e-1)" "unprognostic (6.45e-2)" "unprognostic (4.18e-2)" "potential prognostic favorable (6.91e-5)" "unprognostic (1.82e-2)" "unprognostic (3.30e-2)" "unprognostic (3.71e-2)" "unprognostic (3.62e-3)" "unprognostic (6.10e-2)" "unprognostic (2.57e-2)" "unprognostic (3.00e-1)" "unprognostic (1.47e-1)" "unprognostic (2.41e-1)" "unprognostic (1.98e-1)" "potential prognostic unfavorable (2.61e-4)" "unprognostic (4.65e-2)" "unprognostic (7.46e-2)" "potential prognostic favorable (4.46e-4)" "unprognostic (8.28e-2)" "unprognostic (6.81e-2)" "unprognostic (1.52e-1)" "unprognostic (2.83e-1)" "unprognostic (8.48e-2)" "unprognostic (4.20e-1)" ATL3 DKFZP564J0863 ENSG00000184743 "Atlastin GTPase 3" Q6DD88 11 63624087-63671921 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Hydrolase "Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 318.9;Late spermatids: 1114.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Skeletal muscle - Endothelial cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065702, HPA076616" Enhanced "Endoplasmic reticulum" NA NA 61000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 30: White matter - Myelination" "Cluster 24: Non-specific - Unknown function" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 49 "Endoplasmic reticulum" "HPA065702: , HPA076616: " "unprognostic (6.87e-2)" "unprognostic (8.20e-3)" "unprognostic (4.37e-3)" "unprognostic (1.03e-2)" "unprognostic (3.88e-1)" "unprognostic (7.45e-3)" "unprognostic (1.37e-1)" "potential prognostic unfavorable (6.26e-4)" "unprognostic (5.62e-3)" "unprognostic (5.59e-3)" "potential prognostic favorable (8.78e-5)" "unprognostic (2.02e-1)" "unprognostic (2.80e-1)" "unprognostic (3.04e-3)" "unprognostic (7.09e-2)" "unprognostic (2.36e-3)" "unprognostic (1.31e-2)" "unprognostic (9.77e-2)" "unprognostic (1.55e-2)" "unprognostic (7.34e-2)" "unprognostic (1.26e-1)" "potential prognostic unfavorable (5.90e-5)" "unprognostic (1.78e-1)" "unprognostic (2.80e-1)" "unprognostic (1.98e-1)" "unprognostic (9.83e-2)" "unprognostic (1.45e-1)" "unprognostic (4.60e-2)" "unprognostic (3.77e-1)" "unprognostic (2.34e-1)" "unprognostic (9.99e-2)" ATM "ATA, ATC, ATD, ATDC, TEL1, TELO1" ENSG00000149311 "ATM serine/threonine kinase" Q13315 11 108223044-108369102 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA damage" "DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Neurodegeneration, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglia: 697.0;NK-cells: 485.7" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 888.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000102, HPA067142, CAB080442" Supported Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 24: Non-specific - Unknown function" "Cluster 9: T-cells - Adaptive immunity: Regulation" 135 "Nucleoplasm, Vesicles" "Golgi apparatus" "CAB000102: , CAB080442: , HPA067142: " "unprognostic (2.69e-1)" "unprognostic (6.32e-2)" "unprognostic (1.94e-2)" "unprognostic (9.50e-2)" "unprognostic (1.70e-2)" "unprognostic (2.85e-1)" "unprognostic (1.03e-1)" "unprognostic (1.12e-2)" "unprognostic (2.20e-2)" "potential prognostic unfavorable (1.16e-4)" "unprognostic (8.17e-2)" "unprognostic (1.58e-2)" "unprognostic (1.01e-1)" "unprognostic (1.09e-3)" "unprognostic (3.25e-1)" "unprognostic (1.53e-1)" "unprognostic (1.11e-2)" "unprognostic (1.86e-1)" "unprognostic (2.19e-1)" "unprognostic (2.65e-1)" "unprognostic (9.19e-2)" "unprognostic (1.70e-1)" "potential prognostic unfavorable (4.46e-4)" "unprognostic (2.44e-2)" "potential prognostic favorable (7.18e-4)" "unprognostic (3.20e-3)" "unprognostic (4.43e-2)" "unprognostic (2.30e-1)" "unprognostic (3.00e-1)" "unprognostic (1.18e-1)" "unprognostic (1.31e-1)" ATMIN "ASCIZ, KIAA0431, ZNF822" ENSG00000166454 "ATM interactor" O43313 16 81035842-81047350 "Predicted intracellular proteins" "DNA damage, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 225.0;Late spermatids: 438.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054967, HPA066900" Approved Supported "Nuclear bodies" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 1: Neurons - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 11 "Nuclear bodies" "HPA054967: , HPA066900: " "unprognostic (1.71e-2)" "unprognostic (5.63e-2)" "unprognostic (6.20e-2)" "unprognostic (9.87e-2)" "unprognostic (1.25e-1)" "unprognostic (1.27e-2)" "unprognostic (1.24e-1)" "unprognostic (1.27e-2)" "unprognostic (1.48e-2)" "unprognostic (2.43e-2)" "potential prognostic favorable (1.12e-5)" "unprognostic (5.95e-2)" "unprognostic (5.26e-2)" "unprognostic (1.66e-2)" "unprognostic (7.87e-2)" "unprognostic (6.49e-2)" "unprognostic (3.96e-3)" "unprognostic (1.11e-1)" "unprognostic (2.37e-1)" "unprognostic (4.29e-2)" "unprognostic (7.49e-3)" "unprognostic (1.88e-1)" "unprognostic (2.78e-2)" "unprognostic (5.57e-2)" "unprognostic (4.10e-2)" "unprognostic (2.89e-3)" "unprognostic (1.20e-1)" "unprognostic (2.18e-1)" "unprognostic (4.14e-1)" "unprognostic (3.16e-1)" "unprognostic (2.09e-2)" ATN1 "B37, D12S755E, DRPLA" ENSG00000111676 "Atrophin 1" P54259 12 6924463-6942321 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Disease variant, Epilepsy, Intellectual disability, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Pancreas - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023990, HPA031619" Enhanced Enhanced Nucleoplasm NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 38: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 33 Nucleoplasm "HPA023990: , HPA031619: " "unprognostic (3.98e-2)" "unprognostic (1.72e-1)" "unprognostic (1.88e-1)" "unprognostic (1.21e-2)" "unprognostic (3.34e-2)" "unprognostic (2.50e-1)" "unprognostic (3.90e-2)" "unprognostic (1.21e-1)" "unprognostic (1.52e-1)" "unprognostic (2.43e-1)" "unprognostic (3.32e-2)" "unprognostic (1.07e-2)" "unprognostic (3.15e-1)" "potential prognostic unfavorable (7.75e-4)" "unprognostic (2.78e-1)" "unprognostic (2.99e-1)" "unprognostic (5.80e-3)" "unprognostic (1.81e-1)" "unprognostic (2.41e-1)" "unprognostic (4.04e-2)" "unprognostic (2.98e-2)" "unprognostic (1.30e-1)" "unprognostic (2.87e-2)" "unprognostic (5.38e-2)" "unprognostic (1.32e-1)" "unprognostic (2.43e-2)" "unprognostic (8.32e-2)" "unprognostic (3.08e-2)" "unprognostic (1.43e-1)" "unprognostic (3.47e-2)" "unprognostic (1.81e-1)" ATOH1 "bHLHa14, HATH1, MATH-1, Math1" ENSG00000172238 "Atonal bHLH transcription factor 1" Q92858 4 93828753-93830964 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "intestine: 18.9" "Cell type enriched" "Detected in some" 18 "Goblet cells: 287.6" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Colon Adenocarcinoma (TCGA): 13.3;Rectum Adenocarcinoma (TCGA): 8.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "colorectal cancer: 3.7;Gastric cancer: 1.0;lung cancer: 3.7" "Colon - Colon enterocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA065568, HPA065775" Approved Nucleoplasm,Cytosol NA NA "Cluster 77: Intestine - Digestion" "Cluster 11: Neuronal - Sensory perception" "Cluster 70: Intestinal goblet cells - Mucin production" 3 Nucleoplasm Cytosol "HPA065568: , HPA065775: " "potential prognostic favorable (6.91e-4)" "unprognostic (1.08e-1)" "unprognostic (4.03e-1)" "unprognostic (6.77e-2)" "unprognostic (4.07e-1)" "unprognostic (3.03e-2)" "potential prognostic unfavorable (9.29e-6)" "unprognostic (1.29e-1)" ATOH7 "bHLHa13, Math5" ENSG00000179774 "Atonal bHLH transcription factor 7" Q8N100 10 68230595-68232113 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 3.0;kidney: 1.2;liver: 2.9" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 3.1;Brain inhibitory neurons: 1.2;Epididymal principal cells: 1.2;Granulosa cells: 1.6;Hepatocytes: 1.6;Other brain neurons: 1.2;Undifferentiated spermatogonia: 2.1" "Cell type enhanced" "Detected in many" "deep-layer near-projecting: 17.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lung cancer: 1.0" "Kidney - Proximal tubular cells" "Region enriched" "Detected in some" 9 "cerebellum: 28.7" "Low region specificity" "Detected in some" HPA027008 Uncertain Supported "Nucleoplasm,Cytosol,Flagellar centriole,Mid piece" NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 34: Non-specific - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 35: Neurons - Synaptic function & neurogenesis" "Nucleoplasm, Flagellar centriole" "Cytosol, Mid piece" "HPA027008: " ATOH8 "bHLHa21, FLJ14708, HATH6" ENSG00000168874 "Atonal bHLH transcription factor 8" Q96SQ7 2 85751344-85791383 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 16.2;skeletal muscle: 17.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 52.2;Endometrial glandular cells: 41.9;Hepatocytes: 54.9;Late spermatids: 48.6;Myosatellite cells: 74.1;Pituicytes/FSCs: 121.7;Podocytes: 66.6;Prostatic club cells: 38.0;Schwann cells: 44.4;Thymic myoid cells: 47.6;Vascular endothelial cells: 51.2" "Group enriched" "Detected in many" 4 "astrocyte: 18.2;Bergmann glia: 11.6;committed oligodendrocyte precursor: 24.7;endothelial cell: 35.5;fibroblast: 11.2;oligodendrocyte precursor cell: 34.0;vascular associated smooth muscle cell: 24.6" "Cancer enhanced" "Detected in some" "Thyroid Carcinoma (TCGA): 5.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Adipocytes (Breast), Skin - Macrophages, Spleen - Fibroblasts_2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA028406 Supported Nucleoplasm NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 65: Non-specific - Unknown function" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" Nucleoplasm "HPA028406: " "potential prognostic favorable (1.06e-4)" "unprognostic (4.71e-2)" "potential prognostic favorable (4.24e-5)" "potential prognostic favorable (1.30e-9)" "unprognostic (4.50e-3)" "unprognostic (3.91e-2)" "potential prognostic favorable (1.96e-4)" "unprognostic (2.41e-3)" "potential prognostic favorable (6.49e-5)" "unprognostic (1.50e-1)" "unprognostic (6.47e-2)" "unprognostic (1.01e-1)" "unprognostic (9.59e-2)" "unprognostic (4.40e-2)" ATOSA "FAM214A, FLJ10980, KIAA1370" ENSG00000047346 "Atos homolog A" Q32MH5 15 52581317-52709817 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 471.8;Endometrial glandular cells: 663.4;Esophageal apical cells: 518.0;Myonuclei: 723.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039369, HPA040180" Approved Approved Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 51: Secretory epithelial cells - Mixed function" 5 Nucleoplasm "HPA039369: , HPA040180: " "unprognostic (1.33e-1)" "unprognostic (1.36e-1)" "potential prognostic unfavorable (2.42e-4)" "unprognostic (4.59e-1)" "unprognostic (2.50e-1)" "unprognostic (1.11e-1)" "unprognostic (3.79e-3)" "unprognostic (9.39e-2)" "unprognostic (1.64e-2)" "potential prognostic favorable (1.66e-6)" "unprognostic (1.42e-3)" "unprognostic (8.76e-2)" "unprognostic (5.97e-2)" "unprognostic (4.14e-3)" "unprognostic (4.43e-2)" "unprognostic (5.09e-2)" "unprognostic (3.27e-1)" "unprognostic (2.56e-1)" "unprognostic (4.14e-1)" "unprognostic (1.14e-1)" "unprognostic (4.58e-3)" "unprognostic (1.42e-1)" "unprognostic (7.92e-2)" "unprognostic (1.05e-1)" "unprognostic (5.91e-2)" "unprognostic (2.84e-1)" "unprognostic (2.25e-1)" "unprognostic (1.58e-1)" "unprognostic (2.44e-1)" ATOSB "bA182N22.6, FAM214B, FLJ11560, KIAA1539" ENSG00000005238 "Atos homolog B" Q7L5A3 9 35104112-35116341 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 150.8;Late spermatids: 151.4;Megakaryocytes: 111.3;Neutrophils: 97.3;Platelets: 196.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 16.3" "Group enriched" "Detected in many" 5 "dendritic cells: 4.8;granulocytes: 16.3;monocytes: 10.3" "Low cancer specificity" "Detected in all" "Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048831, HPA055751" Approved Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 47: Platelets - Hemostasis" 53 "Nucleoplasm, Nucleoli fibrillar center" "HPA048831: , HPA055751: " "unprognostic (1.03e-1)" "unprognostic (8.65e-3)" "unprognostic (1.40e-1)" "unprognostic (1.63e-1)" "unprognostic (1.16e-1)" "unprognostic (2.16e-1)" "unprognostic (1.63e-1)" "unprognostic (3.09e-1)" "unprognostic (1.65e-2)" "unprognostic (1.37e-1)" "unprognostic (1.83e-1)" "unprognostic (1.97e-3)" "unprognostic (1.24e-3)" "unprognostic (3.20e-1)" "unprognostic (1.52e-2)" "unprognostic (9.45e-2)" "unprognostic (3.36e-1)" "unprognostic (1.81e-1)" "unprognostic (2.01e-2)" "unprognostic (5.22e-2)" "unprognostic (2.38e-3)" "unprognostic (2.45e-2)" "unprognostic (7.27e-2)" "unprognostic (2.25e-1)" "unprognostic (9.18e-2)" "unprognostic (1.72e-1)" "unprognostic (1.84e-1)" "potential prognostic unfavorable (5.85e-5)" "unprognostic (1.00e-1)" ATOX1 HAH1 ENSG00000177556 "Antioxidant 1 copper chaperone" O00244 5 151742316-151772532 "Predicted intracellular proteins" "Copper transport, Ion transport, Transport" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Enterocytes: 683.6;Esophageal apical cells: 617.2;Hepatocytes: 1056.5;Hofbauer cells: 985.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "skin cancer: 986.8" "Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" HPA055036 Approved "Nucleoplasm,Plasma membrane" NA NA 390000 "Cluster 29: Non-specific - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 27: Non-specific - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 93: Hepatocytes - Bile production & excretion" 10 Nucleoplasm "Plasma membrane" "HPA055036: " "unprognostic (3.85e-2)" "potential prognostic unfavorable (9.60e-4)" "unprognostic (1.37e-1)" "unprognostic (8.68e-2)" "unprognostic (1.56e-1)" "unprognostic (4.18e-3)" "unprognostic (1.33e-1)" "unprognostic (3.37e-1)" "unprognostic (5.73e-2)" "unprognostic (5.40e-2)" "unprognostic (1.17e-1)" "unprognostic (8.98e-3)" "unprognostic (7.70e-2)" "unprognostic (3.35e-1)" "unprognostic (1.27e-2)" "unprognostic (1.41e-2)" "unprognostic (8.27e-2)" "unprognostic (2.63e-1)" "unprognostic (1.54e-2)" "unprognostic (7.84e-2)" "unprognostic (1.66e-1)" "unprognostic (1.00e-2)" "unprognostic (2.03e-1)" "unprognostic (1.44e-1)" "unprognostic (4.86e-2)" "unprognostic (3.11e-3)" "unprognostic (2.68e-2)" "unprognostic (3.39e-2)" "unprognostic (3.97e-2)" "unprognostic (1.27e-1)" "unprognostic (9.63e-2)" ATP10A "ATP10C, ATPVA, ATPVC, KIAA0566" ENSG00000206190 "ATPase phospholipid transporting 10A (putative)" O60312 15 25677273-25865184 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 19.1" "Cell type enriched" "Detected in many" 5 "Podocytes: 2438.8" "Cell type enriched" "Detected in many" 6 "endothelial cell: 2806.9" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 11.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Pituitary gland - Endothelial cells, Skeletal muscle - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041496, HPA042509" Uncertain NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 104: Brain endothelial cells - Blood brain barrier" 1 "HPA041496: , HPA042509: " "unprognostic (6.18e-2)" "unprognostic (1.39e-1)" "unprognostic (6.74e-2)" "potential prognostic unfavorable (4.75e-4)" "unprognostic (4.64e-3)" "unprognostic (1.08e-1)" "unprognostic (1.30e-2)" "unprognostic (5.74e-2)" "unprognostic (1.39e-1)" "unprognostic (1.10e-1)" "unprognostic (1.24e-1)" "unprognostic (7.45e-2)" "unprognostic (1.43e-1)" "unprognostic (4.24e-3)" "unprognostic (1.19e-2)" "unprognostic (1.37e-1)" "unprognostic (1.13e-1)" "unprognostic (1.33e-2)" "unprognostic (7.30e-2)" "unprognostic (5.32e-1)" "unprognostic (8.96e-2)" "unprognostic (3.22e-1)" "unprognostic (4.28e-2)" "unprognostic (3.07e-1)" "unprognostic (1.64e-1)" "unprognostic (1.64e-2)" "unprognostic (2.17e-1)" "unprognostic (1.42e-3)" ATP10B "ATPVB, FLJ21477, KIAA0715" ENSG00000118322 "ATPase phospholipid transporting 10B (putative)" O94823 5 160563120-160852214 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 15.6;intestine: 42.9" "Cell type enhanced" "Detected in many" "Bergmann glia: 888.9;Colonocytes: 221.3;Esophageal apical cells: 276.0;Foveolar cells: 289.6;Oligodendrocyte progenitor cells: 331.4;Oligodendrocytes: 504.8;Retinal pigment epithelial cells: 2621.7" "Cell type enhanced" "Detected in all" "Bergmann glia: 948.7;oligodendrocyte: 772.5;oligodendrocyte precursor cell: 307.7" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 43.5;Rectum Adenocarcinoma (TCGA): 44.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 7.2;colorectal cancer: 14.8" "Colon - Colon enterocytes, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA034574 Uncertain NA NA "Cluster 17: Intestine - Digestion" "Cluster 30: White matter - Myelination" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" "HPA034574: " "unprognostic (5.25e-2)" "unprognostic (1.68e-1)" "unprognostic (1.67e-2)" "potential prognostic favorable (4.33e-4)" "unprognostic (4.43e-3)" "unprognostic (2.06e-1)" "unprognostic (1.61e-2)" "unprognostic (6.98e-2)" "unprognostic (2.41e-1)" "unprognostic (7.46e-2)" "unprognostic (1.80e-1)" "unprognostic (1.15e-1)" "unprognostic (3.03e-2)" "unprognostic (1.72e-2)" "potential prognostic favorable (1.43e-4)" "potential prognostic favorable (8.89e-4)" "unprognostic (7.37e-2)" "unprognostic (1.87e-1)" "unprognostic (1.11e-1)" "unprognostic (3.71e-1)" ATP10D "ATPVD, KIAA1487" ENSG00000145246 "ATPase phospholipid transporting 10D (putative)" Q9P241 4 47485275-47593486 "Enzymes, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 211.4;Leydig cells: 223.3;Pituicytes/FSCs: 206.0;Podocytes: 247.8;Syncytiotrophoblasts: 614.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 18.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 12 "basophil: 84.5" "Lineage enriched" "Detected in all" 12 "granulocytes: 84.5" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA050808 Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 32: Basophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 36: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" "Nucleoplasm, Plasma membrane" "HPA050808: " "unprognostic (1.53e-1)" "unprognostic (6.67e-2)" "unprognostic (7.05e-2)" "unprognostic (2.29e-1)" "unprognostic (5.43e-2)" "unprognostic (2.27e-1)" "unprognostic (1.82e-1)" "unprognostic (1.29e-1)" "unprognostic (1.51e-1)" "unprognostic (2.08e-2)" "validated prognostic favorable (1.32e-8)" "validated prognostic favorable (2.64e-4)" "unprognostic (3.30e-1)" "unprognostic (1.77e-1)" "unprognostic (9.13e-2)" "unprognostic (9.70e-3)" "unprognostic (1.12e-1)" "unprognostic (1.44e-1)" "unprognostic (1.46e-2)" "unprognostic (1.22e-1)" "unprognostic (1.13e-1)" "unprognostic (3.77e-2)" "unprognostic (1.34e-1)" "unprognostic (1.49e-1)" "unprognostic (2.37e-1)" "unprognostic (1.08e-2)" "unprognostic (9.00e-2)" "unprognostic (8.57e-2)" "potential prognostic unfavorable (6.07e-4)" "unprognostic (3.10e-3)" ATP11A "ATPIH, ATPIS, KIAA1021" ENSG00000068650 "ATPase phospholipid transporting 11A" P98196 13 112690038-112887168 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Deafness, Disease variant, Leukodystrophy, Neuropathy, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 870.3;Alveolar cells type 2: 1064.8;Cone photoreceptor cells: 573.4;Endometrial glandular cells: 1767.9;Endometrial luminal cells: 1206.9;Neutrophils: 682.4;Somatotrophs: 1156.7;Transitional alveolar cells: 712.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035583, HPA035584" Approved Supported "Golgi apparatus,Vesicles" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 35: Non-specific - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 7: Liver cancer - Metabolism" "Cluster 51: Secretory epithelial cells - Mixed function" 8 Vesicles "Golgi apparatus" "HPA035583: , HPA035584: " "unprognostic (4.62e-2)" "unprognostic (3.28e-1)" "unprognostic (5.24e-2)" "unprognostic (2.06e-3)" "unprognostic (9.70e-2)" "unprognostic (6.96e-3)" "unprognostic (8.90e-2)" "unprognostic (3.61e-2)" "unprognostic (7.27e-2)" "unprognostic (2.41e-1)" "validated prognostic favorable (1.81e-10)" "validated prognostic favorable (1.22e-4)" "unprognostic (5.19e-2)" "unprognostic (4.39e-3)" "unprognostic (4.81e-3)" "unprognostic (3.11e-2)" "unprognostic (3.26e-1)" "potential prognostic unfavorable (8.46e-6)" "unprognostic (3.67e-1)" "unprognostic (1.30e-3)" "unprognostic (1.62e-1)" "unprognostic (1.80e-2)" "unprognostic (3.40e-3)" "unprognostic (4.41e-1)" "unprognostic (3.25e-1)" "unprognostic (3.30e-2)" "unprognostic (7.57e-3)" "unprognostic (4.35e-2)" "unprognostic (1.93e-1)" "unprognostic (1.49e-1)" "unprognostic (1.24e-1)" ATP11B "ATPIF, ATPIR, KIAA0956" ENSG00000058063 "ATPase phospholipid transporting 11B (putative)" Q9Y2G3 3 182793503-182921629 "Enzymes, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Esophageal apical cells: 689.2;Neutrophil progenitors: 1086.3;Neutrophils: 2238.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036237, HPA036238" Uncertain Approved "Centriolar satellite,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 63: Non-specific - Protein processing" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 4 "Centriolar satellite, Cytosol" "HPA036237: , HPA036238: " "unprognostic (3.26e-1)" "unprognostic (6.07e-2)" "unprognostic (2.52e-1)" "unprognostic (5.93e-2)" "unprognostic (1.92e-1)" "unprognostic (5.98e-3)" "unprognostic (1.55e-1)" "unprognostic (2.81e-1)" "unprognostic (1.77e-1)" "potential prognostic unfavorable (2.90e-4)" "potential prognostic favorable (1.16e-4)" "unprognostic (1.41e-2)" "unprognostic (1.34e-1)" "unprognostic (5.02e-2)" "unprognostic (1.17e-1)" "unprognostic (2.37e-3)" "unprognostic (2.16e-2)" "unprognostic (3.64e-3)" "unprognostic (6.11e-3)" "unprognostic (4.37e-2)" "unprognostic (2.02e-2)" "potential prognostic unfavorable (8.52e-4)" "unprognostic (5.31e-3)" "unprognostic (3.39e-1)" "unprognostic (1.39e-2)" "unprognostic (7.94e-2)" "unprognostic (1.48e-2)" "unprognostic (2.24e-1)" "unprognostic (2.65e-1)" "unprognostic (1.37e-1)" "unprognostic (2.27e-1)" ATP11C "ATPIG, ATPIQ" ENSG00000101974 "ATPase phospholipid transporting 11C" Q8NB49 X 139726346-139945276 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 45.4" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 40.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Pituitary gland - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030830 Approved NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 44: Non-specific - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 13 "HPA030830: " "unprognostic (2.29e-1)" "unprognostic (2.97e-2)" "unprognostic (3.10e-2)" "unprognostic (1.51e-2)" "unprognostic (9.81e-2)" "unprognostic (1.25e-1)" "unprognostic (3.16e-1)" "unprognostic (2.49e-1)" "unprognostic (2.87e-1)" "unprognostic (3.73e-2)" "potential prognostic favorable (5.06e-5)" "unprognostic (2.84e-1)" "unprognostic (3.61e-2)" "unprognostic (1.98e-1)" "unprognostic (2.57e-2)" "unprognostic (3.94e-2)" "unprognostic (4.40e-3)" "unprognostic (3.39e-2)" "unprognostic (8.78e-2)" "unprognostic (3.09e-1)" "unprognostic (1.20e-1)" "unprognostic (2.12e-2)" "unprognostic (5.80e-2)" "unprognostic (8.73e-3)" "unprognostic (1.80e-2)" "unprognostic (3.81e-2)" "unprognostic (2.69e-2)" "unprognostic (6.13e-2)" "unprognostic (2.05e-1)" "unprognostic (1.17e-1)" "unprognostic (9.65e-2)" ATP12A "ATP1AL1, H-K-ATPase, HK" ENSG00000075673 "ATPase H+/K+ transporting non-gastric alpha2 subunit" P54707 13 24680408-24712472 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Potassium transport, Sodium transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "esophagus: 10.5;kidney: 5.0;lymphoid tissue: 13.9;placenta: 5.2;skin 1: 5.8" "Group enriched" "Detected in some" 5 "Respiratory deuterosomal cells: 145.1;Respiratory secretory cells: 184.7" "Cell type enhanced" "Detected in some" "ependymal cell: 1.8" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 18.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "testis cancer: 4.4" "Lung - Respiratory ciliated cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA039526 Approved Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 55: Lymphoma - Immune response" "Cluster 38: Secretory epithelial cells - Exocrine secretion" "Plasma membrane, Actin filaments" Cytosol "HPA039526: " "unprognostic (7.98e-2)" "unprognostic (9.28e-3)" "unprognostic (4.50e-2)" "unprognostic (3.30e-2)" "potential prognostic favorable (5.59e-4)" "unprognostic (1.98e-2)" "unprognostic (1.72e-1)" "unprognostic (3.59e-1)" "unprognostic (1.27e-1)" "unprognostic (2.41e-1)" "unprognostic (1.94e-1)" "unprognostic (4.48e-2)" ATP13A1 "ATP13A, CGI-152, FLJ31858, KIAA1825" ENSG00000105726 "ATPase 13A1" Q9HD20 19 19645198-19663676 "Plasma proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031798, HPA049717" Approved Approved Vesicles NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 49: Non-specific - Transcription" "Cluster 36: Choroid plexus - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 44: Plasma cells - Antibody production & secretion" 13 Vesicles "HPA031798: , HPA049717: " "unprognostic (6.48e-2)" "unprognostic (9.82e-2)" "unprognostic (3.06e-2)" "unprognostic (1.42e-1)" "unprognostic (4.91e-2)" "unprognostic (1.55e-1)" "unprognostic (2.62e-1)" "unprognostic (4.25e-1)" "unprognostic (2.55e-2)" "unprognostic (9.96e-2)" "unprognostic (6.39e-3)" "unprognostic (5.07e-2)" "unprognostic (2.02e-1)" "unprognostic (1.15e-2)" "unprognostic (3.89e-2)" "unprognostic (2.48e-1)" "unprognostic (8.47e-2)" "unprognostic (2.31e-1)" "unprognostic (6.56e-3)" "unprognostic (2.16e-1)" "unprognostic (3.78e-2)" "unprognostic (2.91e-2)" "unprognostic (1.17e-2)" "unprognostic (1.34e-1)" "unprognostic (1.23e-2)" "potential prognostic favorable (1.28e-5)" "unprognostic (3.46e-1)" "unprognostic (2.89e-2)" "unprognostic (1.32e-1)" "unprognostic (1.07e-1)" "unprognostic (2.02e-1)" ATP13A2 "CLN12, HSA9947, PARK9" ENSG00000159363 "ATPase cation transporting 13A2" Q9NQ11 1 16985958-17011928 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Translocase "Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Neuronal ceroid lipofuscinosis, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 98.1" "Cell type enhanced" "Detected in many" "Other brain neurons: 83.3;pDCs: 90.0;Retinal ganglion cells: 96.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "plasmacytoid DC: 20.7" "Lineage enriched" "Detected in many" 6 "dendritic cells: 20.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037038, CAB037111, HPA050910, HPA054717" Enhanced NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 36: Brain & Liver - Signaling" "Cluster 1: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 109: Neurons - Neuronal signaling" 21 "CAB037038: , CAB037111: , HPA050910: , HPA054717: " "unprognostic (1.42e-1)" "unprognostic (1.60e-1)" "unprognostic (9.78e-2)" "potential prognostic unfavorable (6.71e-4)" "potential prognostic favorable (9.61e-4)" "unprognostic (2.76e-1)" "unprognostic (1.41e-1)" "unprognostic (4.65e-1)" "unprognostic (1.69e-1)" "unprognostic (1.14e-1)" "potential prognostic favorable (4.23e-4)" "unprognostic (1.02e-1)" "unprognostic (2.01e-3)" "potential prognostic unfavorable (9.14e-5)" "unprognostic (1.48e-1)" "unprognostic (1.78e-1)" "unprognostic (6.41e-2)" "unprognostic (5.65e-3)" "unprognostic (6.55e-2)" "unprognostic (1.14e-1)" "unprognostic (1.93e-1)" "unprognostic (7.38e-2)" "unprognostic (1.04e-1)" "unprognostic (1.81e-1)" "unprognostic (1.60e-1)" "unprognostic (2.17e-1)" "unprognostic (2.78e-2)" "unprognostic (3.51e-2)" "unprognostic (1.33e-1)" "unprognostic (3.34e-2)" "unprognostic (7.11e-2)" ATP13A3 AFURS1 ENSG00000133657 "ATPase 13A3" Q9H7F0 3 194402672-194498364 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "cDC: 568.9;Endometrial glandular cells: 981.3;Endometrial luminal cells: 589.5;monocytes: 1057.1;Neutrophils: 2082.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029471 Approved Approved "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 12: Non-specific - Vasculature" "Cluster 63: Non-specific - Protein processing" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 38 Nucleoli "Plasma membrane, Cytosol" "HPA029471: " "unprognostic (3.83e-2)" "unprognostic (1.63e-2)" "unprognostic (7.17e-2)" "unprognostic (2.67e-2)" "unprognostic (2.20e-1)" "unprognostic (4.55e-2)" "unprognostic (8.62e-2)" "unprognostic (7.10e-2)" "unprognostic (3.45e-1)" "potential prognostic unfavorable (7.06e-5)" "unprognostic (1.11e-2)" "unprognostic (2.92e-2)" "unprognostic (5.50e-2)" "unprognostic (2.45e-1)" "unprognostic (1.19e-1)" "unprognostic (1.14e-2)" "unprognostic (1.36e-2)" "unprognostic (1.64e-1)" "unprognostic (2.25e-1)" "unprognostic (2.09e-1)" "unprognostic (1.38e-2)" "validated prognostic unfavorable (3.77e-4)" "validated prognostic unfavorable (9.25e-4)" "unprognostic (5.42e-3)" "unprognostic (1.82e-1)" "unprognostic (2.65e-1)" "unprognostic (2.44e-1)" "unprognostic (2.52e-1)" "unprognostic (2.85e-1)" "unprognostic (1.12e-1)" "unprognostic (3.25e-1)" ATP13A4 "DKFZp761I1011, FLJ37958" ENSG00000127249 "ATPase 13A4" Q4VNC1 3 193398967-193593111 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 61.0;parathyroid gland: 54.9;thyroid gland: 48.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 653.2;Alveolar cells type 2: 205.3;Astrocytes: 640.7;Bergmann glia: 319.3;Choroid plexus epithelial cells: 356.3;Esophageal apical cells: 355.2;Oligodendrocyte progenitor cells: 313.5;Pituicytes/FSCs: 542.5;Transitional alveolar cells: 404.9" "Group enriched" "Detected in all" 6 "astrocyte: 686.2;Bergmann glia: 342.5;choroid plexus epithelial cell: 353.9;oligodendrocyte precursor cell: 341.7" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 65.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 1.6;Gastric cancer: 1.4" "Minor Salivary Gland - Minor salivary gland basal cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" "unprognostic (4.51e-3)" "unprognostic (1.12e-2)" "unprognostic (2.70e-1)" "unprognostic (1.78e-1)" "unprognostic (2.14e-2)" "unprognostic (2.33e-2)" "unprognostic (1.20e-1)" "potential prognostic favorable (4.09e-4)" "unprognostic (3.13e-3)" "potential prognostic favorable (1.06e-4)" "unprognostic (2.06e-3)" "potential prognostic favorable (6.70e-4)" "unprognostic (2.90e-1)" "unprognostic (1.41e-1)" "unprognostic (1.95e-1)" "unprognostic (7.07e-2)" "unprognostic (1.36e-2)" "unprognostic (1.35e-1)" "unprognostic (1.11e-1)" "potential prognostic favorable (1.91e-4)" "unprognostic (3.00e-2)" ATP13A5 FLJ16025 ENSG00000187527 "ATPase 13A5" Q4VNC0 3 193274789-193378820 "Predicted membrane proteins" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "breast: 16.1;choroid plexus: 33.4;salivary gland: 11.0" "Cell type enriched" "Detected in many" 5 "Choroid plexus epithelial cells: 358.8" "Cell type enhanced" "Detected in many" "astrocyte: 70.7;choroid plexus epithelial cell: 225.2" "Cancer enhanced" "Detected in some" "Head and Neck Squamous Cell Carcinoma (TCGA): 4.8" "Region enriched" "Detected in all" 12 "choroid plexus: 81.5" "Immune cell enriched" "Detected in single" 6 "neutrophil: 1.0" "Lineage enriched" "Detected in single" 9 "granulocytes: 1.0" "Cancer enhanced" "Detected in some" "Brain cancer: 1.6;breast cancer: 3.3" "Breast - Breast glandular cells (progenitors), Pituitary gland - Undifferentiated cells (Pituitary gland), Skeletal muscle - Skeletal myocytes, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA031771, HPA031772, HPA031774" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 101: Choroid plexus epithelial cells - Ion transport" "Plasma membrane" Nucleoplasm "HPA031771: , HPA031772: , HPA031774: " "unprognostic (3.72e-2)" "unprognostic (1.17e-1)" "unprognostic (1.03e-3)" "unprognostic (2.41e-3)" "unprognostic (1.72e-3)" "unprognostic (2.56e-1)" "unprognostic (1.34e-1)" "potential prognostic favorable (1.56e-4)" "unprognostic (4.26e-2)" ATP1A1 ENSG00000163399 "ATPase Na+/K+ transporting subunit alpha 1" P05023 1 116372668-116410261 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" Translocase "Cancer-related genes, Charcot-Marie-Tooth disease, Epilepsy, FDA approved drug targets, Intellectual disability, Neurodegeneration, Neuropathy, Primary hypomagnesemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 1394.0" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 1174.7;Distal convoluted tubule cells: 1212.2;Enterocytes: 1869.7;Salivary duct cells: 1630.3;Salivary ionocytes: 1393.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Macrophages, Lung - Alveolar cells type 2, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018702, CAB069993" Enhanced Approved "Vesicles,Plasma membrane" NA NA 780000 "Cluster 33: Non-specific - ATP binding" "Cluster 76: Non-specific - Metabolism" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 70: DU4475 - Unknown function" "Cluster 1: Enterocytes - Absorption and Digestion" 68 "Vesicles, Plasma membrane" "CAB018702: , CAB069993: " "unprognostic (4.76e-1)" "unprognostic (3.62e-1)" "unprognostic (1.57e-1)" "unprognostic (8.64e-2)" "unprognostic (2.17e-2)" "unprognostic (1.14e-1)" "unprognostic (9.16e-2)" "unprognostic (1.72e-2)" "unprognostic (3.44e-1)" "unprognostic (2.06e-2)" "potential prognostic favorable (3.15e-6)" "unprognostic (3.56e-2)" "unprognostic (4.24e-3)" "potential prognostic unfavorable (2.62e-4)" "unprognostic (1.60e-3)" "unprognostic (1.17e-1)" "unprognostic (8.11e-2)" "unprognostic (9.61e-2)" "unprognostic (1.59e-1)" "unprognostic (4.77e-2)" "unprognostic (3.03e-1)" "unprognostic (1.81e-2)" "unprognostic (3.56e-1)" "unprognostic (3.42e-1)" "unprognostic (2.32e-1)" "unprognostic (1.23e-1)" "unprognostic (1.29e-2)" "unprognostic (8.88e-2)" "unprognostic (1.04e-1)" "unprognostic (1.51e-1)" "unprognostic (3.47e-2)" ATP1A2 "FHM2, MHP2" ENSG00000018625 "ATPase Na+/K+ transporting subunit alpha 2" P50993 1 160115759-160143591 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" Translocase "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 582.8;skeletal muscle: 825.7;tongue: 446.6" "Cell type enhanced" "Detected in some" "Adipocytes: 329.9;Astrocytes: 818.3;Bergmann glia: 895.8;Cardiomyocytes: 324.0;Myonuclei: 1204.8;Pericytes: 281.3;Pituicytes/FSCs: 463.0;Schwann cells: 199.7;Thymic myoid cells: 701.6" "Cell type enhanced" "Detected in many" "fibroblast: 1690.7;pericyte: 5546.4" "Cancer enriched" "Detected in many" 20 "Glioblastoma Multiforme (TCGA): 171.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Sarcoma: 2.5;testis cancer: 1.8;thyroid cancer: 1.8" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Pituitary gland - Undifferentiated cells (Pituitary gland), Prostate - Smooth muscle cells, Spleen - Fibroblasts_2, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022230 Enhanced NA NA 450000 "Cluster 25: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 22: Non-specific - Basic cellular functions" 11 "CAB022230: " "unprognostic (4.88e-2)" "unprognostic (1.56e-2)" "unprognostic (1.74e-1)" "unprognostic (1.24e-1)" "unprognostic (2.09e-1)" "unprognostic (8.22e-2)" "unprognostic (6.33e-2)" "unprognostic (8.58e-2)" "potential prognostic favorable (1.95e-4)" "unprognostic (3.33e-2)" "potential prognostic favorable (7.31e-4)" "unprognostic (7.94e-3)" "unprognostic (1.81e-1)" "unprognostic (2.62e-1)" "unprognostic (2.71e-3)" "unprognostic (1.10e-1)" "unprognostic (3.56e-3)" "unprognostic (1.09e-2)" "unprognostic (1.90e-2)" "unprognostic (1.76e-1)" "unprognostic (1.49e-1)" ATP1A3 DYT12 ENSG00000105409 "ATPase Na+/K+ transporting subunit alpha 3" P13637 19 41966582-41997497 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" Translocase "Deafness, Disease variant, Dystonia, Epilepsy, Intellectual disability, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 279.0;heart muscle: 147.7;retina: 271.7" "Group enriched" "Detected in some" 8 "Brain excitatory neurons: 115.6;Brain inhibitory neurons: 169.2;Other brain neurons: 180.2" "Cell type enhanced" "Detected in all" "cerebellar inhibitory: 460.3" "Group enriched" "Detected in many" 6 "Glioblastoma Multiforme (TCGA): 43.7;Kidney Chromophobe (TCGA): 24.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 70.2" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Pituitary gland - Gonadotropes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033630, HPA045367, HPA056446" Enhanced Approved NA NA 580000 "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 1: Neuronal - Visual perception" "Cluster 109: Neurons - Neuronal signaling" 120 "CAB033630: , HPA045367: , HPA056446: " "unprognostic (2.01e-1)" "unprognostic (4.71e-2)" "unprognostic (6.93e-2)" "unprognostic (1.72e-1)" "unprognostic (2.38e-1)" "potential prognostic favorable (2.73e-5)" "unprognostic (5.16e-2)" "unprognostic (3.31e-1)" "unprognostic (1.28e-2)" "unprognostic (2.07e-1)" "potential prognostic unfavorable (3.72e-5)" "unprognostic (3.00e-1)" "unprognostic (1.52e-3)" "unprognostic (1.97e-1)" "potential prognostic favorable (2.62e-4)" "unprognostic (1.91e-2)" "unprognostic (2.11e-1)" ATP1A4 ATP1AL2 ENSG00000132681 "ATPase Na+/K+ transporting subunit alpha 4" Q13733 1 160151586-160186980 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 5.9;testis: 15.4;urinary bladder: 4.8" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 36.5;Early spermatids: 106.3;Extravillous trophoblasts: 21.9;Late primary spermatocytes: 56.7;Mast cells: 20.2;Migrating cytotrophoblasts: 30.8;Myonuclei: 31.0;Syncytiotrophoblasts: 63.9;Urothelial cells: 57.5" "Cell type enhanced" "Detected in some" "astrocyte: 6.2;Bergmann glia: 16.4" "Group enriched" "Detected in some" 4 "Bladder Urothelial Carcinoma (TCGA): 2.4;Breast Invasive Carcinoma (TCGA): 1.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Bladder cancer: 2.5;lymphoma: 1.5;testis cancer: 1.6" "Pituitary gland - Undifferentiated cells (Pituitary gland), Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 69: Urothelial cells - Basic cellular functions" 4 "unprognostic (1.32e-1)" "unprognostic (2.11e-1)" "unprognostic (7.02e-2)" ATP1B1 ATP1B ENSG00000143153 "ATPase Na+/K+ transporting subunit beta 1" P05026 1 169105697-169310992 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Immunity, Innate immunity, Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 1376.9" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 2471.3;Parietal cells: 3521.7;Salivary duct cells: 2049.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 14.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary gland ductal cells, Skin - Eccrine sweat gland cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012911 Enhanced NA NA 710000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 72: Kidney - Transmembrane transport" "Cluster 45: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 97: Non-specific - Cellular respiration" 19 "HPA012911: " "unprognostic (2.46e-1)" "unprognostic (6.54e-2)" "unprognostic (1.87e-1)" "unprognostic (3.58e-2)" "unprognostic (2.20e-2)" "unprognostic (1.08e-1)" "unprognostic (1.68e-1)" "unprognostic (1.69e-2)" "unprognostic (4.46e-3)" "unprognostic (3.67e-2)" "potential prognostic favorable (2.23e-8)" "unprognostic (2.74e-3)" "unprognostic (1.19e-1)" "unprognostic (4.34e-1)" "unprognostic (5.21e-2)" "unprognostic (1.59e-1)" "unprognostic (2.05e-2)" "unprognostic (2.01e-1)" "unprognostic (2.97e-2)" "unprognostic (7.00e-2)" "unprognostic (2.48e-1)" "unprognostic (2.34e-2)" "unprognostic (3.58e-2)" "unprognostic (2.53e-1)" "unprognostic (2.74e-1)" "unprognostic (1.67e-1)" "unprognostic (2.76e-1)" "unprognostic (1.59e-1)" "unprognostic (3.02e-2)" "unprognostic (5.85e-2)" "unprognostic (1.43e-1)" ATP1B2 AMOG ENSG00000129244 "ATPase Na+/K+ transporting subunit beta 2" P14415 17 7646627-7657770 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 9 "brain: 290.0;retina: 570.1" "Group enriched" "Detected in many" 4 "Astrocytes: 353.1;Bergmann glia: 262.5;Cone photoreceptor cells: 202.9;Müller glia: 250.8;Oligodendrocyte progenitor cells: 93.4;Pituicytes/FSCs: 233.6;Retinal bipolar cells: 223.2;Retinal pigment epithelial cells: 213.1;Rod photoreceptor cells: 155.8" "Cell type enhanced" "Detected in all" "astrocyte: 398.8;Bergmann glia: 337.1" "Cancer enriched" "Detected in many" 15 "Glioblastoma Multiforme (TCGA): 303.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "testis cancer: 5.2" "Breast - T-cells, Colon - Enteric glia cells, Liver - Hepatic stellate cells, Minor Salivary Gland - Fibroblasts, Pituitary gland - Undifferentiated cells (Pituitary gland), Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010698 Supported NA NA 95000 "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 1 "HPA010698: " "unprognostic (4.15e-3)" "unprognostic (3.65e-1)" "unprognostic (2.27e-3)" "unprognostic (1.19e-3)" "unprognostic (1.69e-1)" "unprognostic (2.97e-2)" "potential prognostic unfavorable (2.49e-4)" "unprognostic (2.13e-1)" "validated prognostic favorable (5.02e-5)" "validated prognostic favorable (3.17e-4)" "unprognostic (8.48e-2)" "unprognostic (2.69e-1)" "unprognostic (1.42e-2)" "unprognostic (2.78e-3)" "unprognostic (5.98e-3)" "unprognostic (1.94e-1)" "unprognostic (1.01e-1)" "unprognostic (8.53e-2)" "potential prognostic favorable (3.30e-5)" "unprognostic (7.14e-2)" "unprognostic (3.55e-1)" "unprognostic (1.91e-2)" "unprognostic (2.96e-3)" "unprognostic (1.50e-1)" "unprognostic (2.46e-1)" "unprognostic (2.40e-1)" ATP1B3 "CD298, FLJ29027" ENSG00000069849 "ATPase Na+/K+ transporting subunit beta 3" P54709 3 141876124-141926549 "CD markers, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Lactotrophs: 1312.9;Late spermatids: 1625.2;monocytes: 1867.4;Somatotrophs: 3948.2;Vascular smooth muscle cells: 1251.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020697, HPA048963" Enhanced Supported "Plasma membrane" NA NA 52000 "Cluster 33: Non-specific - ATP binding" "Cluster 28: Liver & Adrenal gland - Secretion" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 103: Non-specific - Basic cellular processes" 39 "Plasma membrane" "CAB020697: , HPA048963: " "unprognostic (9.23e-2)" "unprognostic (4.56e-1)" "unprognostic (1.77e-2)" "unprognostic (1.47e-3)" "unprognostic (1.50e-1)" "unprognostic (1.56e-1)" "potential prognostic unfavorable (1.99e-4)" "unprognostic (3.59e-1)" "unprognostic (3.45e-2)" "unprognostic (1.09e-2)" "unprognostic (4.11e-2)" "unprognostic (1.32e-1)" "unprognostic (4.96e-3)" "validated prognostic unfavorable (6.92e-6)" "validated prognostic unfavorable (1.04e-6)" "unprognostic (3.01e-2)" "unprognostic (2.73e-3)" "unprognostic (2.03e-1)" "unprognostic (8.78e-2)" "unprognostic (3.55e-2)" "unprognostic (6.63e-2)" "unprognostic (5.87e-2)" "unprognostic (2.10e-1)" "unprognostic (2.27e-1)" "unprognostic (8.81e-2)" "unprognostic (2.39e-1)" "unprognostic (3.29e-3)" "unprognostic (3.63e-2)" "unprognostic (1.58e-1)" "unprognostic (1.05e-2)" "unprognostic (6.01e-2)" ATP1B4 ENSG00000101892 "ATPase Na+/K+ transporting family member beta 4" Q9UN42 X 120362085-120383249 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 28 "skeletal muscle: 52.1;tongue: 20.1" "Cell type enriched" "Detected in some" 7 "Myonuclei: 241.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 48: Non-specific - Mixed function" "Cluster 55: Myocytes - Oxidative muscle function" 7 ATP23 "KUB3, XRCC6BP1" ENSG00000166896 "ATP23 metallopeptidase and ATP synthase assembly factor homolog" Q9Y6H3 12 57906039-57959148 "Enzymes, Essential proteins, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 6.0" "Group enriched" "Detected in many" 4 "Early spermatids: 58.8;Late primary spermatocytes: 82.6" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in single" 4 "Stomach Adenocarcinoma (TCGA): 1.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "neutrophil: 1.6" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.6" "Low cancer specificity" "Detected in some" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035804, HPA043204" Uncertain Enhanced "Vesicles,Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 67: Testis - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 56: Non-specific - Sensory perception" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 24 "Vesicles, Plasma membrane" "Cell Junctions, Cytosol" "HPA035804: , HPA043204: " "unprognostic (1.03e-1)" "unprognostic (2.77e-1)" "unprognostic (3.40e-1)" "unprognostic (5.81e-2)" "unprognostic (2.30e-2)" "unprognostic (2.78e-2)" ATP2A1 "ATP2A, SERCA1" ENSG00000196296 "ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1" O14983 16 28878405-28904466 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" Translocase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 85 "skeletal muscle: 7723.9;tongue: 2988.7" "Group enriched" "Detected in many" 12 "Myonuclei: 441.7;Thymic myoid cells: 898.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 1.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skeletal muscle - Skeletal myocytes" "Region enriched" "Detected in some" 8 "thalamus: 13.1" "Group enriched" "Detected in some" 6 "basal ganglia: 1.8;cerebral cortex: 2.0;hippocampal formation: 1.7" "CAB002310, CAB032706, HPA066701" Enhanced Approved "Endoplasmic reticulum" NA NA 2500000 "Cluster 13: Non-specific - Mitochondria" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 6: Non-specific - Immune response" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 16 "Endoplasmic reticulum" "CAB002310: , CAB032706: , HPA066701: " "unprognostic (2.31e-3)" "unprognostic (3.01e-1)" "unprognostic (1.83e-1)" "unprognostic (2.26e-3)" "unprognostic (1.89e-3)" "unprognostic (4.78e-2)" "unprognostic (7.22e-2)" "unprognostic (2.21e-1)" "unprognostic (3.07e-1)" "validated prognostic unfavorable (1.40e-6)" "validated prognostic unfavorable (1.25e-4)" "unprognostic (9.87e-2)" "unprognostic (1.74e-2)" "unprognostic (5.98e-2)" "unprognostic (1.95e-1)" "unprognostic (9.97e-2)" "unprognostic (8.37e-3)" "unprognostic (1.17e-2)" "unprognostic (1.49e-1)" "potential prognostic favorable (7.68e-4)" "unprognostic (1.73e-1)" "unprognostic (1.04e-1)" "unprognostic (2.65e-1)" "unprognostic (1.13e-1)" "unprognostic (6.74e-2)" "unprognostic (1.47e-1)" "unprognostic (1.45e-1)" "unprognostic (1.66e-2)" "unprognostic (6.30e-2)" ATP2A2 "ATP2B, DAR, SERCA2" ENSG00000174437 "ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2" P16615 12 110280756-110351093 "Disease related genes, Enzymes, Essential proteins, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" Translocase "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 12 "heart muscle: 941.9;skeletal muscle: 2675.7;tongue: 2586.2" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1387.6;Endometrial ciliated cells: 881.0;Myonuclei: 3843.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062605 Enhanced Uncertain "Nucleoplasm,Plasma membrane,Primary cilium,Perinuclear theca,Mid piece,End piece" NA NA 2900000 "Cluster 33: Non-specific - ATP binding" "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 27: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 55: Myocytes - Oxidative muscle function" 48 "Nucleoplasm, Plasma membrane" "Primary cilium, Perinuclear theca, Mid piece, End piece" "HPA062605: " "unprognostic (2.11e-2)" "unprognostic (5.36e-2)" "unprognostic (4.68e-2)" "unprognostic (2.69e-3)" "unprognostic (2.12e-2)" "unprognostic (4.21e-1)" "unprognostic (4.64e-1)" "unprognostic (1.79e-1)" "unprognostic (4.40e-2)" "unprognostic (1.14e-1)" "potential prognostic favorable (3.94e-5)" "unprognostic (1.95e-3)" "unprognostic (1.64e-1)" "unprognostic (2.62e-1)" "unprognostic (1.26e-2)" "unprognostic (2.30e-1)" "unprognostic (8.97e-2)" "unprognostic (2.72e-2)" "unprognostic (2.24e-1)" "unprognostic (4.04e-2)" "unprognostic (6.81e-3)" "unprognostic (3.32e-3)" "unprognostic (1.92e-1)" "unprognostic (2.88e-1)" "unprognostic (1.16e-1)" "unprognostic (9.84e-3)" "unprognostic (1.27e-1)" "unprognostic (1.97e-1)" "unprognostic (7.70e-2)" "unprognostic (6.33e-2)" "unprognostic (1.96e-1)" ATP2A3 SERCA3 ENSG00000074370 "ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3" Q93084 17 3923870-3964464 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 174.6" "Cell type enhanced" "Detected in many" "B-cells: 146.9;Foveolar cells: 350.4;Goblet cells: 196.9;Megakaryocyte progenitors: 167.4;Neutrophil progenitors: 344.8;Neutrophils: 225.5;Platelets: 556.0;Salivary acinar cells: 153.0;Tuft cells: 726.3" "Cell type enhanced" "Detected in many" "leukocyte: 91.1;pericyte: 29.5;vascular associated smooth muscle cell: 27.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 134.5;lymphoma: 100.6" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - T-cells, Liver - T-cells, Minor Salivary Gland - Minor salivary glandular cells, Skin - Eccrine sweat gland cells, Spleen - B-cells (Spleen), Stomach - Gastric mucous cells" "Region enriched" "Detected in all" 15 "cerebellum: 67.2" "Low region specificity" "Detected in all" "HPA007180, CAB010882" Approved NA NA 6300000 "Cluster 22: Eosinophils - Transcription" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 38: Sub-cortical - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 95: Tuft cells - Chemosensory signaling" 14 "CAB010882: , HPA007180: " "unprognostic (7.27e-2)" "unprognostic (6.03e-2)" "unprognostic (6.76e-2)" "potential prognostic favorable (2.27e-4)" "unprognostic (3.05e-3)" "unprognostic (1.73e-1)" "unprognostic (1.13e-1)" "unprognostic (2.57e-2)" "potential prognostic favorable (4.19e-4)" "unprognostic (9.09e-3)" "potential prognostic favorable (8.67e-6)" "unprognostic (2.86e-3)" "unprognostic (1.89e-1)" "unprognostic (1.93e-2)" "unprognostic (6.61e-3)" "unprognostic (4.07e-2)" "unprognostic (9.54e-2)" "unprognostic (9.11e-3)" "unprognostic (2.58e-1)" "unprognostic (8.97e-3)" "unprognostic (1.16e-2)" "unprognostic (3.38e-3)" "unprognostic (1.82e-1)" "unprognostic (9.39e-2)" "unprognostic (2.61e-2)" "unprognostic (2.62e-3)" "unprognostic (6.42e-2)" "unprognostic (2.29e-1)" "unprognostic (4.65e-2)" "unprognostic (2.20e-1)" "unprognostic (4.04e-1)" ATP2B1 PMCA1 ENSG00000070961 "ATPase plasma membrane Ca2+ transporting 1" P20020 12 89588049-89709366 "Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calmodulin-binding, Translocase" "Disease variant, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 89.1" "Cell type enhanced" "Detected in all" "Brain inhibitory neurons: 761.9;cDC: 982.0;monocytes: 2191.5;Neutrophils: 2144.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005605, HPA011166, HPA012945" Enhanced Supported Supported "Plasma membrane" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 73: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 36 "Plasma membrane" "CAB005605: , HPA011166: , HPA012945: " "unprognostic (1.24e-1)" "unprognostic (4.71e-2)" "unprognostic (6.53e-2)" "unprognostic (2.85e-3)" "unprognostic (3.56e-2)" "unprognostic (7.93e-2)" "unprognostic (2.88e-1)" "unprognostic (1.30e-2)" "unprognostic (2.75e-2)" "unprognostic (6.47e-2)" "potential prognostic favorable (5.04e-4)" "unprognostic (7.25e-2)" "unprognostic (2.93e-1)" "unprognostic (1.01e-3)" "unprognostic (4.45e-3)" "unprognostic (3.47e-3)" "unprognostic (2.10e-3)" "unprognostic (2.62e-2)" "unprognostic (4.16e-3)" "unprognostic (7.60e-3)" "unprognostic (7.71e-3)" "unprognostic (1.85e-1)" "unprognostic (1.29e-2)" "unprognostic (2.85e-1)" "unprognostic (1.04e-1)" "unprognostic (5.50e-2)" "unprognostic (1.56e-2)" "unprognostic (2.65e-2)" "unprognostic (1.90e-1)" "unprognostic (1.16e-1)" "unprognostic (1.08e-2)" ATP2B2 PMCA2 ENSG00000157087 "ATPase plasma membrane Ca2+ transporting 2" Q01814 3 10324023-10708007 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calmodulin-binding, Translocase" "Deafness, Disease variant, FDA approved drug targets, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 88.0;choroid plexus: 61.0;salivary gland: 31.3;skeletal muscle: 35.1" "Cell type enriched" "Detected in many" 4 "Choroid plexus epithelial cells: 1350.6" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 13.5;Liver Hepatocellular Carcinoma (TCGA): 15.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 2.7;Neuroblastoma: 3.3" "Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Corticotropes, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005606 Enhanced NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 18: Liver cancer - Metabolism" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 1 "CAB005606: " "unprognostic (5.30e-2)" "unprognostic (3.02e-1)" "potential prognostic favorable (2.03e-5)" "unprognostic (2.99e-2)" "potential prognostic favorable (7.09e-5)" "unprognostic (9.99e-3)" "unprognostic (1.60e-3)" "unprognostic (1.48e-1)" "unprognostic (1.82e-2)" "unprognostic (1.73e-1)" "unprognostic (2.36e-1)" "unprognostic (2.15e-2)" ATP2B3 "CFAP39, CLA2, PMCA3, SCAX1" ENSG00000067842 "ATPase plasma membrane Ca2+ transporting 3" Q16720 X 153517642-153582939 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calmodulin-binding, Translocase" "Cancer-related genes, Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "choroid plexus: 106.2" "Cell type enriched" "Detected in some" 6 "Choroid plexus epithelial cells: 197.4" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 159.2" "Not detected" "Not detected" "Region enhanced" "Detected in all" "choroid plexus: 503.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 4.9;Neuroblastoma: 9.1" "Adrenal gland - Adrenal cortex cells, Colon - Colon enteroendocrine cells, Pituitary gland - Gonadotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001583, HPA064779" Enhanced Supported Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 3 "Nucleoplasm, Plasma membrane" "HPA001583: , HPA064779: " "unprognostic (1.63e-2)" ATP2B4 "ATP2B2, MXRA1, PMCA4" ENSG00000058668 "ATPase plasma membrane Ca2+ transporting 4" P23634 1 203626832-203744081 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calmodulin-binding, Translocase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "smooth muscle: 164.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 486.4;Basal keratinocytes: 496.5;Smooth muscle cells: 476.1;Suprabasal keratinocytes: 691.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in all" 4 "testis cancer: 204.8" "Prostate - Smooth muscle cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016118, HPA040431" Enhanced Supported "Plasma membrane,Primary cilium,Mitochondria,Basal body" NA NA 58000 "Cluster 33: Non-specific - ATP binding" "Cluster 75: Ovary - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 26: Keratinocytes - Keratinization" 19 "Plasma membrane, Primary cilium" "Mitochondria, Basal body" "CAB016118: , HPA040431: " "unprognostic (3.94e-2)" "unprognostic (2.47e-1)" "unprognostic (1.57e-1)" "unprognostic (2.30e-2)" "unprognostic (3.38e-1)" "unprognostic (1.10e-1)" "unprognostic (1.31e-1)" "unprognostic (2.92e-1)" "unprognostic (1.35e-2)" "unprognostic (1.92e-1)" "potential prognostic favorable (2.76e-5)" "unprognostic (3.87e-2)" "unprognostic (4.62e-2)" "unprognostic (5.16e-2)" "unprognostic (1.95e-1)" "unprognostic (2.91e-1)" "unprognostic (6.45e-2)" "unprognostic (2.55e-2)" "unprognostic (3.33e-1)" "unprognostic (4.89e-2)" "unprognostic (3.97e-2)" "unprognostic (3.61e-2)" "unprognostic (1.38e-1)" "unprognostic (1.01e-1)" "unprognostic (7.18e-2)" "unprognostic (1.78e-2)" "unprognostic (2.33e-1)" "unprognostic (1.47e-2)" "unprognostic (2.94e-1)" "unprognostic (4.82e-2)" "unprognostic (1.37e-1)" ATP2C1 "ATP2C1A, BCPM, KIAA1347, PMR1, SPCA1" ENSG00000017260 "ATPase secretory pathway Ca2+ transporting 1" P98194 3 130850595-131016712 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" Translocase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hematopoietic stem cells: 497.4;Microglia: 540.8;Prostatic glandular cells: 775.9;Sertoli cells: 505.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Prostate glandular cells, Skin - Mitotic cells (Skin), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010207, HPA035116, HPA069684" Supported Supported "Golgi apparatus" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 4 "Golgi apparatus" "CAB010207: , HPA035116: , HPA069684: " "unprognostic (1.66e-1)" "unprognostic (5.05e-2)" "unprognostic (4.18e-2)" "unprognostic (2.42e-2)" "unprognostic (5.00e-2)" "unprognostic (3.67e-2)" "unprognostic (3.53e-1)" "unprognostic (2.02e-2)" "unprognostic (6.72e-3)" "unprognostic (1.40e-1)" "potential prognostic favorable (2.61e-6)" "unprognostic (4.18e-2)" "unprognostic (8.12e-2)" "potential prognostic unfavorable (6.97e-4)" "unprognostic (2.74e-2)" "unprognostic (1.83e-2)" "unprognostic (1.41e-1)" "unprognostic (4.05e-1)" "unprognostic (1.25e-1)" "unprognostic (1.33e-2)" "unprognostic (3.32e-2)" "potential prognostic unfavorable (7.01e-4)" "unprognostic (4.51e-2)" "unprognostic (8.48e-2)" "unprognostic (2.48e-2)" "unprognostic (2.37e-1)" "unprognostic (1.31e-1)" "unprognostic (1.66e-1)" "unprognostic (2.11e-1)" "unprognostic (3.89e-2)" "unprognostic (1.68e-1)" ATP2C2 "KIAA0703, SPCA2" ENSG00000064270 "ATPase secretory pathway Ca2+ transporting 2" O75185 16 84368527-84464187 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" Translocase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 35.1;salivary gland: 19.1;skin 1: 24.5" "Cell type enhanced" "Detected in many" "Breast lactating cells: 411.4;Colonocytes: 152.0;Endometrial glandular cells: 248.4;Enteric stem cells: 211.5;Enteric transient amplifying cells: 193.8;Goblet cells: 228.0;Oligodendrocyte progenitor cells: 194.0;Paneth cells: 127.6;Prostatic glandular cells: 131.9;Respiratory basal cells: 157.9;Respiratory ciliated cells: 189.0;Respiratory deuterosomal cells: 213.5;Respiratory secretory cells: 209.7" "Cell type enhanced" "Detected in many" "deep-layer near-projecting: 170.4;oligodendrocyte precursor cell: 224.5" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 33.0;Rectum Adenocarcinoma (TCGA): 31.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 23.0" "Breast - Breast glandular cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Testis - Late spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA052262, HPA075812" Approved Approved "Plasma membrane,Focal adhesion sites" NA NA "Cluster 77: Intestine - Digestion" "Cluster 24: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 51: Secretory epithelial cells - Mixed function" 1 "Plasma membrane, Focal adhesion sites" "HPA052262: , HPA075812: " "unprognostic (5.22e-2)" "unprognostic (2.33e-2)" "unprognostic (1.94e-1)" "unprognostic (1.71e-1)" "unprognostic (1.76e-2)" "unprognostic (9.94e-2)" "unprognostic (2.13e-2)" "unprognostic (3.55e-1)" "unprognostic (3.05e-2)" "unprognostic (1.14e-1)" "unprognostic (2.47e-1)" "unprognostic (3.39e-3)" "unprognostic (4.37e-1)" "unprognostic (4.96e-2)" "unprognostic (5.58e-2)" "unprognostic (3.10e-2)" "unprognostic (6.33e-1)" "unprognostic (7.39e-2)" "unprognostic (2.44e-3)" "unprognostic (1.38e-3)" "unprognostic (1.61e-1)" "unprognostic (8.25e-3)" "unprognostic (4.20e-2)" ATP4A ATP6A ENSG00000105675 "ATPase H+/K+ transporting subunit alpha" P20648 19 35550031-35563658 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Potassium transport, Transport" Translocase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 81 "stomach 1: 780.3" "Cell type enriched" "Detected in some" 34 "Parietal cells: 4248.3" "Group enriched" "Detected in some" 8 "cerebellar inhibitory: 21.1;upper rhombic lip: 12.6" "Cancer enriched" "Detected in single" 16 "Stomach Adenocarcinoma (TCGA): 5.4" "Region enhanced" "Detected in some" "cerebellum: 2.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adrenal gland - Adrenal cortex cells, Stomach - Parietal cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA039154, HPA076684" Enhanced NA NA "Cluster 60: Stomach - Digestion" "Cluster 2: Neurons - Nucleosome" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 97: Non-specific - Cellular respiration" 10 "HPA039154: , HPA076684: " "unprognostic (9.93e-2)" ATP4B ATP6B ENSG00000186009 "ATPase H+/K+ transporting subunit beta" P51164 13 113648804-113658198 "FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Hydrogen ion transport, Ion transport, Potassium transport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 147 "stomach 1: 1001.8" "Cell type enriched" "Detected in some" 50 "Parietal cells: 7052.1" "Group enriched" "Detected in some" 60 "choroid plexus epithelial cell: 11.8;ependymal cell: 14.8" "Cancer enriched" "Detected in some" 5 "Stomach Adenocarcinoma (TCGA): 4.7" "Region enriched" "Detected in some" 6 "choroid plexus: 7.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Stomach - Parietal cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045400, HPA052649" Enhanced Approved "Plasma membrane" NA NA "Cluster 60: Stomach - Digestion" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 97: Non-specific - Cellular respiration" 3 "Plasma membrane" "HPA045400: , HPA052649: " "unprognostic (2.69e-2)" "unprognostic (2.94e-1)" ATP5F1A "ATP5A, ATP5A1, ATP5AL2, ATPM, hATP1, OMR, ORM" ENSG00000152234 "ATP synthase F1 subunit alpha" P25705 18 46080248-46104334 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" Translocase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 1644.4" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 909.5;Esophageal basal cells: 785.0;Esophageal suprabasal cells: 839.8;Migrating cytotrophoblasts: 803.6;Parietal cells: 912.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Stomach - Parietal cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013067, HPA040622, HPA044202" Enhanced Supported "Mitochondria,End piece" NA NA 10000000 "Cluster 13: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cellular respiration" "Cluster 23: Choroid plexus - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 97: Non-specific - Cellular respiration" 101 Mitochondria "End piece" "CAB013067: , HPA040622: , HPA044202: " "unprognostic (6.94e-2)" "unprognostic (1.33e-2)" "unprognostic (1.24e-1)" "potential prognostic favorable (6.03e-4)" "unprognostic (2.61e-1)" "unprognostic (3.51e-2)" "potential prognostic favorable (7.64e-4)" "unprognostic (2.37e-1)" "unprognostic (2.50e-2)" "potential prognostic favorable (1.15e-9)" "unprognostic (2.70e-3)" "potential prognostic favorable (9.27e-6)" "unprognostic (3.87e-2)" "unprognostic (1.82e-1)" "unprognostic (2.07e-3)" "unprognostic (1.18e-1)" "unprognostic (1.42e-2)" "unprognostic (1.43e-1)" "unprognostic (1.78e-1)" "unprognostic (1.26e-2)" "unprognostic (1.11e-1)" "unprognostic (5.44e-2)" "unprognostic (7.21e-2)" "unprognostic (5.20e-2)" "unprognostic (1.89e-1)" "unprognostic (5.19e-2)" "unprognostic (1.32e-1)" "unprognostic (1.07e-1)" "unprognostic (1.10e-1)" ATP5F1B "ATP5B, ATPSB" ENSG00000110955 "ATP synthase F1 subunit beta" P06576 12 56638175-56645984 "Enzymes, Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" Translocase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 2427.2;tongue: 2993.0" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 974.9;Esophageal basal cells: 1127.5;Esophageal suprabasal cells: 1098.0;Parietal cells: 1278.2;Syncytiotrophoblasts: 1350.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA001520, HPA001528, CAB017527" Enhanced Enhanced Mitochondria NA NA 22000000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 52: Non-specific - Cellular respiration" "Cluster 23: Choroid plexus - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 97: Non-specific - Cellular respiration" 116 Mitochondria "CAB017527: , HPA001520: , HPA001528: " "unprognostic (5.81e-3)" "potential prognostic unfavorable (2.93e-4)" "unprognostic (7.14e-2)" "unprognostic (2.12e-3)" "unprognostic (4.71e-2)" "unprognostic (3.79e-1)" "unprognostic (1.10e-1)" "unprognostic (3.00e-2)" "potential prognostic unfavorable (6.64e-4)" "potential prognostic favorable (6.35e-8)" "unprognostic (4.50e-2)" "unprognostic (5.93e-3)" "unprognostic (4.63e-3)" "potential prognostic unfavorable (3.63e-4)" "unprognostic (4.07e-3)" "unprognostic (1.82e-1)" "unprognostic (4.90e-1)" "unprognostic (2.95e-1)" "unprognostic (4.25e-2)" "unprognostic (5.38e-1)" "unprognostic (2.67e-2)" "unprognostic (3.85e-2)" "unprognostic (5.37e-2)" "unprognostic (4.05e-1)" "unprognostic (2.50e-2)" "unprognostic (1.09e-1)" "unprognostic (2.95e-1)" "unprognostic (7.78e-2)" "unprognostic (3.97e-2)" ATP5F1C "ATP5C, ATP5C1, ATP5CL1" ENSG00000165629 "ATP synthase F1 subunit gamma" P36542 10 7788147-7807815 "Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 834.5" "Cell type enhanced" "Detected in many" "Esophageal suprabasal cells: 717.4;Parietal cells: 1350.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060949 Approved NA NA 270000 "Cluster 33: Non-specific - ATP binding" "Cluster 52: Non-specific - Cellular respiration" "Cluster 25: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 97: Non-specific - Cellular respiration" 49 "HPA060949: " "unprognostic (1.18e-1)" "unprognostic (4.21e-3)" "unprognostic (4.65e-3)" "unprognostic (6.83e-2)" "unprognostic (7.65e-2)" "unprognostic (2.49e-2)" "unprognostic (3.10e-3)" "unprognostic (9.60e-2)" "unprognostic (1.81e-1)" "potential prognostic favorable (1.25e-5)" "unprognostic (4.81e-2)" "unprognostic (3.25e-1)" "unprognostic (5.47e-3)" "unprognostic (3.54e-3)" "unprognostic (7.84e-2)" "unprognostic (1.99e-2)" "unprognostic (6.32e-2)" "unprognostic (1.81e-2)" "unprognostic (6.06e-3)" "unprognostic (9.13e-2)" "unprognostic (3.28e-3)" "unprognostic (3.89e-1)" "unprognostic (1.38e-1)" "unprognostic (1.22e-1)" "unprognostic (3.21e-1)" "unprognostic (2.09e-1)" "unprognostic (2.09e-1)" "unprognostic (2.38e-1)" "unprognostic (3.32e-2)" ATP5F1D ATP5D ENSG00000099624 "ATP synthase F1 subunit delta" P30049 19 1241746-1244825 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 784.2" "Cell type enhanced" "Detected in all" "Colonocytes: 1787.9;Enterocytes: 1696.4;Esophageal basal cells: 1232.1;Esophageal suprabasal cells: 1468.0;Parietal cells: 1729.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002865 Approved Supported "Mitochondria,Connecting piece,Flagellar centriole,Principal piece" NA NA 260000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 30 "Mitochondria, Principal piece" "Connecting piece, Flagellar centriole" "HPA002865: " "unprognostic (1.71e-1)" "unprognostic (7.72e-2)" "unprognostic (4.46e-2)" "unprognostic (8.31e-3)" "unprognostic (1.03e-1)" "unprognostic (1.40e-1)" "unprognostic (5.72e-2)" "unprognostic (1.87e-1)" "unprognostic (1.19e-1)" "unprognostic (1.86e-2)" "unprognostic (1.52e-1)" "potential prognostic favorable (2.63e-4)" "unprognostic (2.70e-2)" "unprognostic (6.54e-3)" "unprognostic (2.12e-1)" "unprognostic (2.19e-1)" "unprognostic (1.92e-1)" "unprognostic (9.80e-2)" "unprognostic (1.04e-1)" "unprognostic (1.25e-2)" "unprognostic (1.58e-1)" "unprognostic (3.84e-1)" "unprognostic (3.90e-1)" "unprognostic (5.57e-2)" "unprognostic (6.66e-2)" "unprognostic (4.40e-1)" "unprognostic (2.50e-1)" "unprognostic (1.31e-1)" "unprognostic (2.84e-1)" ATP5F1E ATP5E ENSG00000124172 "ATP synthase F1 subunit epsilon" P56381 20 59025475-59032345 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" Hydrolase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 3722.0;Hofbauer cells: 3957.3;Megakaryocytes: 4753.7;Parietal cells: 7423.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 62: Non-specific - Plasma proteins" "Cluster 97: Non-specific - Cellular respiration" 6 "unprognostic (1.30e-2)" "unprognostic (2.26e-1)" "unprognostic (2.84e-2)" "unprognostic (9.67e-2)" "unprognostic (1.27e-1)" "unprognostic (9.01e-2)" "unprognostic (2.22e-1)" "unprognostic (1.66e-3)" "unprognostic (2.70e-3)" "unprognostic (1.81e-2)" "potential prognostic unfavorable (8.56e-4)" "unprognostic (2.87e-1)" "unprognostic (3.48e-3)" "unprognostic (2.27e-1)" "unprognostic (2.16e-2)" "unprognostic (7.07e-2)" "unprognostic (1.23e-1)" "unprognostic (6.87e-2)" "unprognostic (4.23e-2)" "unprognostic (5.74e-2)" "unprognostic (1.85e-3)" "unprognostic (4.81e-1)" "unprognostic (8.86e-2)" "unprognostic (4.28e-2)" "unprognostic (7.84e-2)" "unprognostic (7.71e-2)" "unprognostic (3.26e-1)" "unprognostic (8.34e-2)" "unprognostic (1.55e-1)" ATP5IF1 "ATPI, ATPIF1, ATPIP, IP, MGC1167, MGC8898" ENSG00000130770 "ATP synthase inhibitory factor subunit 1" Q9UII2 1 28236109-28246906 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 1499.2;Endometrial ciliated cells: 759.2;Granulosa cells: 715.3;Late primary spermatocytes: 2589.3;Parietal cells: 705.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027999 Supported Enhanced Mitochondria NA NA 74000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 14: Neurons - Synaptic function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 54 Mitochondria "HPA027999: " "unprognostic (1.38e-1)" "unprognostic (1.91e-2)" "unprognostic (3.37e-2)" "unprognostic (2.66e-1)" "unprognostic (1.08e-2)" "potential prognostic unfavorable (3.78e-5)" "unprognostic (7.99e-2)" "unprognostic (1.47e-1)" "unprognostic (2.45e-1)" "unprognostic (1.48e-2)" "unprognostic (7.12e-2)" "unprognostic (2.16e-3)" "unprognostic (9.38e-2)" "unprognostic (9.82e-2)" "unprognostic (1.16e-2)" "unprognostic (2.39e-2)" "unprognostic (3.32e-1)" "unprognostic (3.21e-2)" "unprognostic (2.10e-1)" "unprognostic (2.09e-2)" "unprognostic (1.11e-1)" "unprognostic (4.57e-1)" "unprognostic (6.21e-2)" "unprognostic (8.09e-2)" "unprognostic (6.57e-2)" "unprognostic (5.79e-2)" "unprognostic (3.21e-1)" "unprognostic (1.42e-1)" "unprognostic (5.06e-3)" ATP5MC1 "ATP5G, ATP5G1" ENSG00000159199 "ATP synthase membrane subunit c locus 1" P05496 17 48892765-48895871 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 1208.5" "Cell type enhanced" "Detected in many" "Enteric stem cells: 633.2;Enteric transient amplifying cells: 863.3;Esophageal basal cells: 819.5;Esophageal suprabasal cells: 797.2;Gastric progenitor cells: 699.8;Parietal cells: 1624.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cellular respiration" "Cluster 14: Neurons - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 11 "potential prognostic unfavorable (3.58e-4)" "unprognostic (1.48e-1)" "potential prognostic favorable (3.53e-5)" "unprognostic (3.35e-3)" "unprognostic (1.25e-1)" "unprognostic (6.05e-2)" "unprognostic (1.01e-1)" "unprognostic (5.02e-2)" "unprognostic (5.62e-2)" "unprognostic (1.41e-1)" "unprognostic (2.29e-3)" "unprognostic (6.22e-2)" "unprognostic (2.96e-2)" "unprognostic (5.27e-3)" "unprognostic (9.42e-2)" "unprognostic (6.47e-2)" "unprognostic (6.52e-3)" "unprognostic (8.66e-2)" "unprognostic (1.32e-1)" "unprognostic (9.27e-2)" "unprognostic (1.23e-2)" "unprognostic (7.08e-2)" "unprognostic (1.68e-1)" "unprognostic (2.09e-1)" "unprognostic (3.25e-1)" "unprognostic (9.31e-3)" "unprognostic (4.79e-1)" "unprognostic (1.72e-1)" "unprognostic (2.58e-1)" ATP5MC2 ATP5G2 ENSG00000135390 "ATP synthase membrane subunit c locus 2" Q06055 12 53632726-53677408 "Essential proteins, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Parietal cells: 1709.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051469 Approved NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 7: Non-specific - Ribosome" "Cluster 38: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" "HPA051469: " "potential prognostic unfavorable (5.95e-4)" "unprognostic (2.62e-1)" "unprognostic (1.85e-3)" "unprognostic (1.56e-1)" "unprognostic (3.72e-2)" "unprognostic (3.25e-1)" "unprognostic (5.52e-1)" "unprognostic (1.54e-2)" "unprognostic (3.71e-3)" "unprognostic (2.02e-2)" "unprognostic (1.43e-3)" "unprognostic (1.36e-2)" "potential prognostic unfavorable (3.95e-4)" "potential prognostic unfavorable (3.10e-4)" "unprognostic (4.19e-2)" "unprognostic (4.14e-2)" "unprognostic (2.34e-1)" "unprognostic (1.19e-2)" "unprognostic (2.54e-1)" "unprognostic (1.36e-1)" "unprognostic (2.55e-1)" "unprognostic (2.22e-1)" "unprognostic (6.78e-2)" "unprognostic (6.61e-2)" "unprognostic (5.27e-1)" "unprognostic (1.16e-1)" "unprognostic (3.12e-1)" "unprognostic (2.71e-1)" "unprognostic (6.40e-2)" ATP5MC3 ATP5G3 ENSG00000154518 "ATP synthase membrane subunit c locus 3" P48201 2 175176258-175181710 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Disease variant, Dystonia, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1149.4;tongue: 1014.6" "Cell type enhanced" "Detected in all" "Colonocytes: 1455.0;Enteric transient amplifying cells: 1479.1;Enterocytes: 1330.1;Esophageal basal cells: 1736.7;Esophageal suprabasal cells: 1722.4;Parietal cells: 3390.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cellular respiration" "Cluster 45: Non-specific - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 97: Non-specific - Cellular respiration" 1 "unprognostic (4.33e-2)" "unprognostic (3.38e-3)" "unprognostic (1.10e-1)" "unprognostic (1.85e-3)" "unprognostic (9.29e-3)" "unprognostic (1.22e-1)" "unprognostic (1.77e-2)" "unprognostic (3.79e-3)" "unprognostic (8.99e-3)" "unprognostic (3.60e-3)" "unprognostic (8.69e-2)" "potential prognostic favorable (8.58e-4)" "unprognostic (4.17e-3)" "unprognostic (2.73e-3)" "unprognostic (2.60e-1)" "unprognostic (1.49e-1)" "unprognostic (8.37e-2)" "unprognostic (2.14e-1)" "unprognostic (1.00e-1)" "unprognostic (3.63e-2)" "unprognostic (3.53e-1)" "unprognostic (2.68e-1)" "unprognostic (2.20e-1)" "unprognostic (2.28e-2)" "potential prognostic unfavorable (7.56e-4)" "unprognostic (2.16e-2)" "unprognostic (7.37e-2)" "unprognostic (2.12e-2)" "unprognostic (1.85e-1)" ATP5ME ATP5I ENSG00000169020 "ATP synthase membrane subunit e" P56385 4 672436-674330 "Metabolic proteins, Predicted intracellular proteins, Transporters" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 1506.0;Enterocytes: 2035.5;Hepatocytes: 3036.6;Parietal cells: 4661.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035010 Enhanced Supported Mitochondria NA NA 140000 "Cluster 29: Non-specific - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 97: Non-specific - Cellular respiration" 22 Mitochondria "HPA035010: " "unprognostic (4.36e-2)" "unprognostic (3.06e-1)" "potential prognostic favorable (3.66e-4)" "unprognostic (2.78e-2)" "potential prognostic favorable (1.93e-4)" "unprognostic (2.13e-2)" "unprognostic (2.20e-1)" "potential prognostic unfavorable (6.96e-5)" "unprognostic (3.86e-1)" "unprognostic (1.00e-1)" "unprognostic (1.38e-2)" "unprognostic (7.60e-3)" "unprognostic (1.08e-1)" "unprognostic (4.04e-2)" "unprognostic (7.15e-2)" "unprognostic (9.93e-2)" "unprognostic (3.68e-2)" "unprognostic (5.41e-3)" "unprognostic (2.05e-2)" "unprognostic (4.55e-2)" "unprognostic (1.86e-1)" "unprognostic (7.72e-2)" "unprognostic (7.17e-2)" "unprognostic (8.80e-3)" "unprognostic (4.36e-2)" "unprognostic (3.17e-2)" "unprognostic (2.66e-1)" "unprognostic (1.46e-1)" "unprognostic (2.68e-1)" ATP5MF "ATP5J2, ATP5JL" ENSG00000241468 "ATP synthase membrane subunit f" P56134 7 99448475-99466186 "Essential proteins, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 1019.7;Esophageal suprabasal cells: 844.4;Gastric progenitor cells: 1499.6;Hofbauer cells: 813.6;Megakaryocytes: 846.9;Parietal cells: 1083.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Prostate - Prostate glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067267, HPA070412" Approved Supported "Nuclear membrane,Mitochondria" NA NA 47000 "Cluster 29: Non-specific - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 23: Choroid plexus - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 3 Mitochondria "Nuclear membrane" "HPA067267: , HPA070412: " "unprognostic (3.22e-2)" "unprognostic (3.79e-2)" "unprognostic (1.03e-1)" "unprognostic (2.11e-1)" "unprognostic (2.86e-2)" "unprognostic (7.85e-3)" "unprognostic (4.37e-2)" "potential prognostic unfavorable (9.13e-7)" "potential prognostic unfavorable (1.77e-7)" "potential prognostic unfavorable (1.56e-4)" "unprognostic (6.33e-3)" "unprognostic (2.68e-2)" "unprognostic (8.38e-3)" "unprognostic (6.71e-3)" "unprognostic (8.74e-2)" "unprognostic (3.75e-3)" "unprognostic (1.48e-1)" "unprognostic (3.36e-2)" "unprognostic (3.58e-1)" "unprognostic (1.81e-1)" "unprognostic (9.86e-2)" "unprognostic (6.94e-2)" "unprognostic (3.34e-2)" "unprognostic (6.54e-2)" "unprognostic (6.81e-3)" "unprognostic (3.15e-1)" "unprognostic (3.26e-1)" "unprognostic (4.69e-1)" "unprognostic (2.20e-1)" ATP5MF-PTCD1 ATP5J2-PTCD1 ENSG00000248919 "ATP5MF-PTCD1 readthrough" 7 99419749-99466197 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in single" 4 "Oocytes: 4.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA020106, HPA047679" Uncertain Approved Mitochondria NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 39: Non-specific - Transcription" "Cluster 41: Oocytes - Oogenesis" 2 Mitochondria "HPA020106: , HPA047679: " "unprognostic (5.76e-2)" "unprognostic (6.82e-2)" "unprognostic (8.55e-2)" "unprognostic (4.45e-2)" "unprognostic (2.84e-1)" "unprognostic (1.82e-1)" "unprognostic (2.22e-1)" "unprognostic (1.02e-2)" "potential prognostic favorable (7.10e-5)" "unprognostic (4.14e-2)" "unprognostic (8.27e-2)" "unprognostic (1.26e-1)" "unprognostic (1.54e-2)" "unprognostic (6.52e-3)" "unprognostic (3.34e-3)" "unprognostic (4.72e-2)" "unprognostic (5.45e-3)" "unprognostic (6.84e-3)" "unprognostic (1.49e-1)" "unprognostic (5.95e-2)" "unprognostic (3.05e-1)" "unprognostic (2.66e-1)" "unprognostic (3.24e-1)" "unprognostic (7.21e-2)" "unprognostic (4.73e-2)" "unprognostic (2.93e-1)" "unprognostic (1.51e-1)" ATP5MG "ATP5JG, ATP5L" ENSG00000167283 "ATP synthase membrane subunit g" O75964 11 118401346-118433278 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Parietal cells: 2796.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Testis - Early spermatids" HPA044629 Approved Supported "Mitochondria,Principal piece" NA NA 130000 "Cluster 13: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cellular respiration" "Cluster 23: Choroid plexus - Mixed function" "Cluster 25: Non-specific - Ribosome" "Cluster 97: Non-specific - Cellular respiration" 25 Mitochondria "Principal piece" "HPA044629: " "unprognostic (2.45e-1)" "unprognostic (1.69e-1)" "unprognostic (1.63e-1)" "unprognostic (1.17e-1)" "unprognostic (5.26e-3)" "unprognostic (2.29e-1)" "unprognostic (2.17e-1)" "unprognostic (8.84e-2)" "unprognostic (2.33e-3)" "unprognostic (6.24e-3)" "unprognostic (1.84e-1)" "unprognostic (1.08e-3)" "potential prognostic unfavorable (4.83e-5)" "unprognostic (9.52e-3)" "unprognostic (2.25e-1)" "unprognostic (8.58e-2)" "unprognostic (1.47e-1)" "unprognostic (4.68e-2)" "unprognostic (1.42e-1)" "unprognostic (2.78e-1)" "unprognostic (5.59e-1)" "unprognostic (5.23e-2)" "unprognostic (2.09e-1)" "unprognostic (7.65e-2)" "unprognostic (2.16e-3)" "unprognostic (6.94e-2)" "unprognostic (1.78e-1)" "unprognostic (1.32e-1)" "unprognostic (5.63e-2)" ATP5MGL "ATP5K2, ATP5L2, dJ222E13.5" ENSG00000249222 "ATP synthase membrane subunit g like" Q7Z4Y8 22 42639803-42640601 "Metabolic proteins, Predicted membrane proteins" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "bone marrow: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA044629 Uncertain Approved "Mitochondria,Principal piece" NA NA "Cluster 40: Non-specific - Mixed function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 56: Non-specific - Sensory perception" Mitochondria "Principal piece" "HPA044629: " "unprognostic (2.04e-3)" "unprognostic (1.18e-2)" "unprognostic (2.19e-3)" "unprognostic (6.80e-3)" ATP5MJ "6.8PL, ATP5MPL, C14orf2, MLQ, MP68" ENSG00000156411 "ATP synthase membrane subunit j" P56378 14 103912288-103928269 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal suprabasal cells: 1177.6;Hofbauer cells: 1211.9;Parietal cells: 2367.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058978, HPA060520" Approved Supported "Nucleoli fibrillar center,Mitochondria" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 14: Neurons - Synaptic function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 97: Non-specific - Cellular respiration" 2 Mitochondria "Nucleoli fibrillar center" "HPA058978: , HPA060520: " "unprognostic (1.69e-3)" "unprognostic (1.83e-1)" "unprognostic (5.88e-3)" "unprognostic (1.10e-1)" "unprognostic (4.31e-1)" "unprognostic (1.28e-1)" "unprognostic (1.58e-2)" "unprognostic (6.31e-3)" "unprognostic (3.15e-2)" "unprognostic (1.82e-1)" "unprognostic (1.14e-1)" "unprognostic (2.92e-1)" "unprognostic (1.71e-3)" "unprognostic (6.16e-3)" "unprognostic (3.58e-1)" "unprognostic (9.72e-3)" "unprognostic (3.72e-1)" "unprognostic (8.84e-3)" "unprognostic (3.97e-2)" "unprognostic (8.26e-3)" "unprognostic (4.13e-2)" "unprognostic (1.51e-1)" "unprognostic (2.04e-1)" "unprognostic (3.23e-2)" "unprognostic (1.71e-2)" "unprognostic (5.29e-2)" "unprognostic (9.47e-2)" "unprognostic (3.27e-1)" "unprognostic (4.53e-2)" ATP5MK "AGP, ATP5MD, bA792D24.4, DAPIT, MGC14697, USMG5" ENSG00000173915 "ATP synthase membrane subunit k" Q96IX5 10 103389041-103396492 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Colonocytes: 1411.5;Esophageal apical cells: 1869.9;Esophageal suprabasal cells: 1633.0;Hepatocytes: 2167.6;Parietal cells: 6412.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044798 Supported Mitochondria NA NA 14000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 52: Non-specific - Cellular respiration" "Cluster 14: Neurons - Synaptic function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 97: Non-specific - Cellular respiration" 3 Mitochondria "HPA044798: " "unprognostic (1.34e-2)" "unprognostic (1.76e-3)" "unprognostic (1.32e-3)" "unprognostic (6.33e-2)" "unprognostic (5.09e-2)" "unprognostic (1.85e-1)" "unprognostic (3.30e-2)" "unprognostic (6.58e-3)" "unprognostic (1.27e-1)" "unprognostic (8.30e-2)" "unprognostic (2.14e-2)" "unprognostic (1.91e-1)" "unprognostic (7.25e-2)" "unprognostic (1.63e-3)" "unprognostic (4.01e-1)" "unprognostic (1.13e-1)" "unprognostic (1.77e-1)" "unprognostic (4.04e-2)" "unprognostic (1.13e-2)" "unprognostic (4.62e-2)" "unprognostic (1.74e-2)" "unprognostic (1.89e-1)" "unprognostic (4.59e-2)" "unprognostic (2.05e-1)" "unprognostic (6.59e-2)" "unprognostic (1.33e-1)" "unprognostic (4.95e-3)" "unprognostic (7.47e-2)" "unprognostic (5.04e-2)" ATP5PB ATP5F1 ENSG00000116459 "ATP synthase peripheral stalk-membrane subunit b" P24539 1 111448864-111462773 "Essential proteins, Metabolic proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 127.5;tongue: 122.9" "Cell type enhanced" "Detected in all" "Esophageal suprabasal cells: 586.0;Late primary spermatocytes: 583.9;Parietal cells: 899.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046067, HPA057347" Enhanced Supported Mitochondria NA NA 91000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 37: Non-specific - mRNA processing" "Cluster 97: Non-specific - Cellular respiration" 113 Mitochondria "HPA046067: , HPA057347: " "unprognostic (2.73e-1)" "unprognostic (5.29e-2)" "unprognostic (1.11e-2)" "unprognostic (3.19e-3)" "unprognostic (1.33e-1)" "unprognostic (1.74e-1)" "unprognostic (2.76e-1)" "unprognostic (5.02e-2)" "potential prognostic unfavorable (5.58e-4)" "validated prognostic favorable (3.65e-13)" "validated prognostic favorable (5.29e-5)" "unprognostic (2.22e-1)" "unprognostic (1.63e-1)" "unprognostic (1.22e-1)" "unprognostic (2.68e-2)" "unprognostic (3.69e-2)" "unprognostic (2.39e-1)" "unprognostic (1.69e-1)" "unprognostic (2.26e-1)" "unprognostic (5.62e-2)" "unprognostic (4.89e-1)" "unprognostic (6.19e-2)" "unprognostic (1.95e-3)" "unprognostic (1.05e-1)" "unprognostic (1.17e-2)" "unprognostic (8.96e-2)" "unprognostic (8.26e-2)" "unprognostic (2.66e-1)" "unprognostic (1.64e-1)" ATP5PD "ATP5H, ATP5JD, ATPQ" ENSG00000167863 "ATP synthase peripheral stalk subunit d" O75947 17 75038863-75046985 "Essential proteins, Metabolic proteins, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 936.0;Esophageal basal cells: 687.4;Esophageal suprabasal cells: 1018.9;Parietal cells: 937.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042777, HPA048459" Enhanced Supported Mitochondria NA NA 86000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 27: Breast cancer - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 39 Mitochondria "HPA042777: , HPA048459: " "unprognostic (7.76e-2)" "unprognostic (4.14e-1)" "unprognostic (1.08e-3)" "unprognostic (4.23e-3)" "unprognostic (3.13e-1)" "unprognostic (1.73e-2)" "unprognostic (8.97e-2)" "potential prognostic unfavorable (1.04e-4)" "unprognostic (4.12e-2)" "unprognostic (4.98e-2)" "unprognostic (9.78e-2)" "unprognostic (8.09e-2)" "potential prognostic unfavorable (2.95e-4)" "unprognostic (6.95e-3)" "unprognostic (4.09e-2)" "unprognostic (1.60e-1)" "unprognostic (1.73e-1)" "unprognostic (1.48e-2)" "unprognostic (5.71e-2)" "unprognostic (8.63e-2)" "unprognostic (1.32e-1)" "unprognostic (5.20e-2)" "unprognostic (5.23e-2)" "unprognostic (2.81e-1)" "unprognostic (2.11e-1)" "unprognostic (2.79e-1)" "unprognostic (1.99e-1)" "unprognostic (2.32e-1)" "unprognostic (1.57e-2)" ATP5PF "ATP5, ATP5A, ATP5J, ATPM, CF6" ENSG00000154723 "ATP synthase peripheral stalk subunit F6" P18859 21 25716503-25735673 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 1487.1" "Cell type enhanced" "Detected in many" "Esophageal suprabasal cells: 1306.6;Hepatocytes: 1869.1;Parietal cells: 2635.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031069 Supported Supported "Mitochondria,Flagellar centriole,End piece" NA NA 240000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 47: Leukemia - Hemostasis" "Cluster 97: Non-specific - Cellular respiration" 81 Mitochondria "Flagellar centriole, End piece" "HPA031069: " "unprognostic (1.31e-1)" "potential prognostic unfavorable (5.28e-4)" "unprognostic (6.96e-3)" "unprognostic (1.39e-1)" "unprognostic (2.18e-1)" "unprognostic (1.35e-1)" "unprognostic (3.70e-2)" "potential prognostic unfavorable (3.13e-4)" "unprognostic (2.41e-1)" "potential prognostic favorable (1.01e-6)" "unprognostic (1.43e-1)" "unprognostic (4.85e-2)" "unprognostic (2.40e-1)" "unprognostic (1.42e-3)" "unprognostic (8.45e-2)" "unprognostic (2.36e-1)" "unprognostic (1.09e-1)" "unprognostic (9.66e-2)" "unprognostic (3.75e-1)" "unprognostic (1.02e-1)" "unprognostic (2.46e-1)" "unprognostic (3.31e-1)" "unprognostic (3.18e-2)" "unprognostic (3.47e-2)" "unprognostic (1.51e-1)" "unprognostic (6.88e-2)" "unprognostic (1.77e-1)" "unprognostic (4.50e-1)" "unprognostic (2.04e-1)" ATP5PO "ATP5O, ATPO, OSCP" ENSG00000241837 "ATP synthase peripheral stalk subunit OSCP" P48047 21 33903453-33915814 "Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 1494.1" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 770.7;Esophageal basal cells: 774.3;Esophageal suprabasal cells: 989.4;Late primary spermatocytes: 769.1;Parietal cells: 1591.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016209, HPA041394" Enhanced Approved Mitochondria NA NA 110000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 47: Leukemia - Hemostasis" "Cluster 97: Non-specific - Cellular respiration" 72 Mitochondria "CAB016209: , HPA041394: " "unprognostic (1.43e-1)" "unprognostic (4.15e-3)" "unprognostic (1.67e-2)" "unprognostic (1.44e-1)" "unprognostic (5.03e-2)" "unprognostic (1.04e-1)" "unprognostic (2.16e-1)" "unprognostic (3.06e-2)" "unprognostic (4.36e-2)" "potential prognostic favorable (1.51e-4)" "unprognostic (4.84e-2)" "potential prognostic favorable (3.73e-4)" "unprognostic (7.51e-2)" "unprognostic (4.75e-2)" "unprognostic (1.04e-1)" "unprognostic (1.10e-1)" "unprognostic (3.56e-1)" "unprognostic (2.48e-1)" "unprognostic (4.67e-1)" "unprognostic (1.83e-1)" "unprognostic (8.47e-2)" "unprognostic (1.77e-1)" "unprognostic (9.20e-2)" "unprognostic (3.04e-2)" "unprognostic (5.03e-3)" "unprognostic (2.03e-2)" "unprognostic (9.92e-2)" "unprognostic (4.53e-2)" "unprognostic (2.14e-2)" ATP6AP1 "16A, Ac45, ATP6IP1, ATP6S1, CF2, ORF, VATPS1, XAP-3, XAP3" ENSG00000071553 "ATPase H+ transporting accessory protein 1" Q15904 X 154428633-154436516 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 334.3;Hofbauer cells: 310.1;Syncytiotrophoblasts: 230.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Breast - Breast glandular cells, Lung - Macrophages, Spleen - Macrophages, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB015218 Approved NA NA 520000 "Cluster 29: Non-specific - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 14: Neurons - Synaptic function" "Cluster 36: Non-specific - mRNA processing" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 49 "CAB015218: " "unprognostic (4.23e-2)" "potential prognostic unfavorable (4.41e-5)" "unprognostic (8.39e-2)" "unprognostic (2.14e-1)" "unprognostic (4.64e-2)" "unprognostic (1.55e-3)" "unprognostic (2.39e-2)" "unprognostic (3.78e-2)" "unprognostic (8.56e-3)" "unprognostic (6.51e-2)" "potential prognostic favorable (2.45e-7)" "unprognostic (1.86e-2)" "unprognostic (6.49e-2)" "unprognostic (1.02e-3)" "potential prognostic unfavorable (2.93e-4)" "unprognostic (3.76e-1)" "unprognostic (3.50e-1)" "unprognostic (1.98e-2)" "unprognostic (3.05e-1)" "unprognostic (3.30e-1)" "unprognostic (2.45e-1)" "unprognostic (1.10e-2)" "unprognostic (1.83e-1)" "unprognostic (7.28e-2)" "unprognostic (6.58e-3)" "unprognostic (1.11e-1)" "unprognostic (2.40e-1)" "unprognostic (1.18e-1)" "unprognostic (6.10e-2)" "unprognostic (3.61e-1)" "unprognostic (2.01e-1)" ATP6AP2 "APT6M8-9, ATP6IP2, ATP6M8-9, M8-9, PRR, RENR" ENSG00000182220 "ATPase H+ transporting accessory protein 2" O75787 X 40579372-40606848 "Disease related genes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Congenital disorder of glycosylation, Disease variant, Epilepsy, Intellectual disability, Neurodegeneration, Parkinsonism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "parathyroid gland: 719.4" "Cell type enhanced" "Detected in all" "Epididymal clear cells: 455.2;Hofbauer cells: 1184.9;Kupffer cells: 417.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 382.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003156 Approved NA NA 160000 "Cluster 29: Non-specific - Unknown function" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 14: Neurons - Synaptic function" "Cluster 36: Non-specific - mRNA processing" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 151 "HPA003156: " "unprognostic (1.88e-2)" "unprognostic (2.81e-1)" "unprognostic (1.72e-1)" "unprognostic (3.46e-2)" "unprognostic (2.50e-2)" "unprognostic (1.12e-2)" "unprognostic (1.83e-2)" "unprognostic (2.36e-3)" "unprognostic (1.22e-1)" "unprognostic (4.46e-2)" "potential prognostic favorable (3.99e-6)" "unprognostic (1.65e-1)" "unprognostic (7.01e-2)" "potential prognostic unfavorable (3.59e-4)" "unprognostic (1.14e-2)" "unprognostic (1.67e-1)" "unprognostic (1.25e-1)" "unprognostic (2.96e-1)" "unprognostic (1.16e-1)" "unprognostic (1.25e-1)" "unprognostic (6.54e-3)" "unprognostic (1.03e-1)" "unprognostic (3.31e-1)" "unprognostic (9.23e-2)" "unprognostic (1.52e-1)" "unprognostic (1.54e-3)" "potential prognostic unfavorable (2.77e-4)" "unprognostic (1.62e-1)" "unprognostic (1.02e-2)" "unprognostic (9.50e-2)" "unprognostic (1.41e-1)" ATP6V0A1 "a1, ATP6N1, ATP6N1A, Stv1, Vph1, VPP1" ENSG00000033627 "ATPase H+ transporting V0 subunit a1" Q93050 17 42458844-42522582 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 98.9" "Cell type enhanced" "Detected in all" "Rod photoreceptor cells: 409.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022144 Enhanced Approved "Nuclear speckles,Golgi apparatus,Vesicles,Cytosol" NA NA 6500 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 79: Photoreceptor cells - Phototransduction" 53 "Golgi apparatus, Vesicles" "Nuclear speckles, Cytosol" "HPA022144: " "unprognostic (1.06e-1)" "unprognostic (9.02e-3)" "unprognostic (2.36e-2)" "unprognostic (7.27e-3)" "unprognostic (5.14e-2)" "unprognostic (4.57e-2)" "unprognostic (1.52e-1)" "unprognostic (1.84e-2)" "unprognostic (8.46e-2)" "unprognostic (3.15e-2)" "potential prognostic favorable (9.79e-8)" "unprognostic (8.12e-3)" "unprognostic (1.91e-1)" "unprognostic (9.55e-2)" "unprognostic (1.80e-2)" "unprognostic (8.57e-2)" "unprognostic (8.14e-2)" "unprognostic (2.47e-2)" "unprognostic (1.08e-1)" "unprognostic (3.07e-2)" "unprognostic (6.82e-2)" "unprognostic (1.67e-3)" "unprognostic (5.98e-2)" "unprognostic (1.17e-1)" "unprognostic (3.52e-3)" "unprognostic (5.15e-3)" "unprognostic (3.08e-1)" "unprognostic (4.18e-1)" "unprognostic (2.04e-1)" "unprognostic (6.16e-2)" "unprognostic (8.55e-3)" ATP6V0A2 "a2, a2V, ATP6a2, ATP6N1D, J6B7, RTF, Stv1, TJ6, TJ6M, TJ6s, Vph1" ENSG00000185344 "ATPase H+ transporting V0 subunit a2" Q9Y487 12 123712353-123761755 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hematopoietic stem cells: 126.2;Mast cells: 178.8;Megakaryocyte progenitors: 168.3;Megakaryocyte-Erythroid progenitors: 174.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 13.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044279 Approved Supported "Vesicles,Plasma membrane,Focal adhesion sites,Connecting piece,Mid piece,Principal piece,End piece" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 49: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 58: Mast cells - Allergic inflammatory responses" 73 "Plasma membrane, Connecting piece, Mid piece" "Vesicles, Focal adhesion sites, Principal piece, End piece" "HPA044279: " "unprognostic (2.45e-1)" "unprognostic (3.01e-1)" "unprognostic (2.05e-1)" "unprognostic (2.74e-1)" "unprognostic (4.70e-2)" "unprognostic (3.28e-1)" "unprognostic (1.69e-1)" "unprognostic (2.48e-1)" "unprognostic (3.83e-2)" "unprognostic (1.76e-3)" "unprognostic (2.68e-1)" "unprognostic (8.66e-2)" "unprognostic (1.24e-1)" "potential prognostic unfavorable (2.75e-5)" "unprognostic (1.37e-2)" "unprognostic (7.01e-2)" "unprognostic (2.86e-1)" "unprognostic (3.35e-2)" "unprognostic (1.16e-1)" "unprognostic (1.72e-1)" "unprognostic (5.19e-2)" "unprognostic (4.66e-3)" "unprognostic (1.85e-1)" "unprognostic (2.14e-1)" "unprognostic (8.81e-3)" "unprognostic (1.18e-2)" "unprognostic (1.05e-3)" "unprognostic (2.22e-2)" "unprognostic (4.34e-2)" "unprognostic (6.28e-2)" "unprognostic (4.83e-2)" ATP6V0A4 "a4, ATP6N1B, ATP6N2, RDRTA2, RTA1C, RTADR, Stv1, Vph1, VPP2" ENSG00000105929 "ATPase H+ transporting V0 subunit a4" Q9HBG4 7 138706294-138799560 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "kidney: 59.4;salivary gland: 73.9" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 560.6;Epididymal clear cells: 277.6;Lacrimal acinar cells: 152.2;Loop of henle epithelial cells: 161.4;Renal collecting duct intercalated cells: 1092.1;Renal collecting duct principal cells: 182.8;Renal connecting tubule cells: 362.3;Respiratory ionocytes: 203.2;Salivary duct cells: 308.5;Salivary ionocytes: 224.0" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 10.8;oligodendrocyte precursor cell: 13.2" "Cancer enriched" "Detected in many" 28 "Kidney Chromophobe (TCGA): 468.3" "Region enriched" "Detected in some" 5 "choroid plexus: 7.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 10.7;Gastric cancer: 9.7;skin cancer: 8.2" "Breast - Breast glandular cells (progenitors), Kidney - Intercalated cells, Minor Salivary Gland - Minor salivary gland basal cells, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018029, HPA064555" Enhanced Uncertain Cytosol NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 22 Cytosol "HPA018029: , HPA064555: " "potential prognostic unfavorable (4.42e-4)" "unprognostic (1.10e-2)" "unprognostic (4.78e-2)" "unprognostic (4.35e-3)" "unprognostic (4.66e-2)" "unprognostic (1.18e-1)" "unprognostic (6.29e-3)" "unprognostic (9.58e-3)" "unprognostic (1.18e-1)" "unprognostic (3.42e-2)" "unprognostic (1.00e-1)" "unprognostic (1.63e-2)" "unprognostic (4.78e-2)" "unprognostic (7.62e-2)" "unprognostic (2.20e-1)" ATP6V0B "ATP6F, HATPL, VMA16" ENSG00000117410 "ATPase H+ transporting V0 subunit b" Q99437 1 43974487-43978295 "Essential proteins, Metabolic proteins, Predicted membrane proteins" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epididymal clear cells: 843.1;Hofbauer cells: 860.9;Neutrophils: 768.3;Respiratory ionocytes: 1325.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 2279.8" "Group enriched" "Detected in all" 4 "dendritic cells: 771.1;granulocytes: 2279.8;monocytes: 1048.7" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Breast - Breast glandular cells, Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044281 Approved Cytosol NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 27: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 20 Cytosol "HPA044281: " "unprognostic (4.57e-3)" "unprognostic (9.74e-2)" "unprognostic (1.39e-2)" "unprognostic (4.80e-2)" "unprognostic (5.79e-2)" "unprognostic (7.90e-2)" "unprognostic (3.84e-2)" "unprognostic (8.22e-2)" "unprognostic (1.67e-2)" "unprognostic (3.48e-1)" "potential prognostic favorable (9.16e-4)" "unprognostic (6.09e-2)" "potential prognostic favorable (3.86e-4)" "validated prognostic unfavorable (5.79e-5)" "validated prognostic unfavorable (1.39e-4)" "unprognostic (7.25e-2)" "unprognostic (1.43e-1)" "unprognostic (1.56e-1)" "unprognostic (3.04e-2)" "unprognostic (3.24e-2)" "unprognostic (1.06e-3)" "unprognostic (3.25e-3)" "unprognostic (1.95e-1)" "unprognostic (1.34e-1)" "unprognostic (1.08e-2)" "unprognostic (7.86e-2)" "unprognostic (7.84e-3)" "unprognostic (3.40e-2)" "unprognostic (1.29e-1)" "unprognostic (1.29e-1)" "unprognostic (1.56e-1)" ATP6V0C "ATP6C, ATP6L, ATPL, VATL, Vma3" ENSG00000185883 "ATPase H+ transporting V0 subunit c" P27449 16 2513952-2520218 "Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction, Hydrogen ion transport, Ion transport, Transport" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 56.4;Bergmann glia: 52.1;Brain excitatory neurons: 200.0;Brain inhibitory neurons: 238.8;Ependymal cells: 68.7;Microglia: 83.4;Oligodendrocyte progenitor cells: 80.9;Oligodendrocytes: 112.7;Other brain neurons: 308.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 1478.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Lung - Macrophages, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065100 Approved Vesicles NA NA 170000 "Cluster 25: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 54: Non-specific - Transcription" "Cluster 98: Neurons - Neurotransmission & signaling" 117 Vesicles "HPA065100: " "unprognostic (2.77e-1)" "unprognostic (2.24e-2)" "unprognostic (1.34e-1)" "unprognostic (6.20e-2)" "unprognostic (1.81e-1)" "unprognostic (1.60e-2)" "potential prognostic unfavorable (8.26e-5)" "unprognostic (3.18e-1)" "unprognostic (4.01e-2)" "unprognostic (8.99e-2)" "potential prognostic favorable (1.22e-4)" "unprognostic (7.27e-2)" "unprognostic (1.14e-1)" "unprognostic (1.57e-2)" "potential prognostic unfavorable (6.74e-4)" "unprognostic (2.68e-2)" "unprognostic (2.18e-2)" "unprognostic (9.58e-3)" "unprognostic (2.33e-1)" "unprognostic (2.28e-1)" "unprognostic (1.05e-1)" "unprognostic (1.59e-1)" "unprognostic (4.62e-2)" "unprognostic (5.46e-2)" "unprognostic (6.04e-3)" "unprognostic (3.09e-1)" "unprognostic (1.60e-2)" "unprognostic (2.76e-1)" "unprognostic (3.90e-3)" "unprognostic (1.14e-1)" "unprognostic (1.32e-1)" ATP6V0D1 "ATP6D, ATP6DV, P39, VATX, Vma6, VPATPD" ENSG00000159720 "ATPase H+ transporting V0 subunit d1" P61421 16 67438014-67481181 "Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Cilium biogenesis/degradation, Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 364.3;Neutrophils: 666.7;Syncytiotrophoblasts: 418.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016938 Uncertain NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 1: Neurons - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 72 "HPA016938: " "unprognostic (1.09e-1)" "potential prognostic unfavorable (5.28e-4)" "unprognostic (3.04e-1)" "unprognostic (6.73e-2)" "unprognostic (8.77e-2)" "unprognostic (8.32e-2)" "unprognostic (6.28e-2)" "unprognostic (1.23e-2)" "unprognostic (7.93e-2)" "unprognostic (2.52e-2)" "potential prognostic favorable (1.60e-5)" "unprognostic (6.92e-2)" "potential prognostic favorable (1.97e-4)" "potential prognostic unfavorable (5.63e-5)" "unprognostic (6.95e-2)" "unprognostic (1.78e-2)" "unprognostic (1.16e-1)" "unprognostic (7.75e-3)" "unprognostic (2.72e-2)" "unprognostic (1.93e-1)" "unprognostic (1.46e-1)" "unprognostic (2.12e-3)" "unprognostic (3.19e-1)" "unprognostic (2.15e-2)" "unprognostic (3.93e-2)" "unprognostic (1.31e-1)" "unprognostic (1.39e-1)" "unprognostic (9.60e-2)" "unprognostic (1.32e-1)" "unprognostic (2.28e-2)" "unprognostic (2.17e-2)" ATP6V0D2 "ATP6D2, FLJ38708, VMA6" ENSG00000147614 "ATPase H+ transporting V0 subunit d2" Q8N8Y2 8 85987323-86154225 "Metabolic proteins, Predicted intracellular proteins" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "kidney: 56.4" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 329.1;Distal convoluted tubule cells: 184.0;Epididymal clear cells: 792.0;Renal collecting duct intercalated cells: 1373.2;Respiratory ionocytes: 154.9;Rod photoreceptor cells: 299.3;Salivary ionocytes: 191.1" "Cell type enhanced" "Detected in some" "committed oligodendrocyte precursor: 5.3;oligodendrocyte: 13.4" "Cancer enriched" "Detected in many" 31 "Kidney Chromophobe (TCGA): 632.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "skin cancer: 5.3;testis cancer: 5.3" "Kidney - Intercalated cells, Minor Salivary Gland - Minor salivary gland ductal cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA055327, HPA058496" Enhanced Approved Vesicles NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 72: Kidney - Transmembrane transport" "Cluster 6: Non-specific - Immune response" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 41 Vesicles "HPA055327: , HPA058496: " "unprognostic (1.49e-1)" "unprognostic (5.70e-2)" "unprognostic (4.45e-1)" "unprognostic (2.74e-2)" "unprognostic (1.24e-1)" "unprognostic (2.78e-1)" "unprognostic (3.22e-2)" "unprognostic (6.70e-2)" "unprognostic (1.66e-1)" "unprognostic (2.93e-2)" "unprognostic (2.81e-2)" "unprognostic (3.14e-2)" "unprognostic (1.55e-2)" "unprognostic (2.14e-2)" "unprognostic (2.09e-2)" "unprognostic (8.72e-2)" "unprognostic (2.75e-1)" "unprognostic (2.80e-2)" "unprognostic (6.04e-2)" "unprognostic (1.26e-1)" "unprognostic (9.06e-2)" "unprognostic (8.72e-2)" "unprognostic (8.82e-2)" "unprognostic (6.63e-2)" "unprognostic (8.91e-2)" "unprognostic (9.77e-2)" "unprognostic (2.63e-1)" ATP6V0E1 "ATP6H, ATP6V0E, M9.2" ENSG00000113732 "ATPase H+ transporting V0 subunit e1" O15342 5 172983771-173035445 "Metabolic proteins, Predicted membrane proteins" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 1872.9;Neutrophils: 1158.7;Syncytiotrophoblasts: 1114.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Macrophages, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 22: Epididymis - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 13 "unprognostic (1.36e-1)" "unprognostic (1.99e-1)" "unprognostic (1.19e-1)" "unprognostic (1.58e-1)" "unprognostic (1.67e-1)" "unprognostic (2.46e-2)" "unprognostic (1.09e-2)" "unprognostic (4.19e-3)" "potential prognostic unfavorable (2.34e-6)" "unprognostic (4.77e-2)" "unprognostic (6.41e-2)" "unprognostic (5.50e-2)" "unprognostic (4.09e-2)" "potential prognostic unfavorable (2.68e-5)" "unprognostic (2.06e-2)" "unprognostic (1.10e-2)" "unprognostic (2.26e-1)" "unprognostic (1.84e-1)" "unprognostic (1.56e-3)" "unprognostic (1.84e-1)" "potential prognostic unfavorable (3.56e-4)" "unprognostic (1.25e-1)" "unprognostic (8.47e-2)" "unprognostic (1.50e-1)" "unprognostic (1.23e-1)" "unprognostic (2.85e-1)" "unprognostic (1.63e-1)" "unprognostic (1.47e-2)" "unprognostic (7.99e-2)" "unprognostic (1.29e-1)" "unprognostic (2.57e-1)" ATP6V0E2 "ATP6V0E2L, C7orf32" ENSG00000171130 "ATPase H+ transporting V0 subunit e2" Q8NHE4 7 149872968-149891204 "Predicted membrane proteins" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 373.7" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 120.0;Brain inhibitory neurons: 98.4;Müller glia: 116.5;Other brain neurons: 140.5;Retinal pigment epithelial cells: 187.6" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 323.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 27: Cerebellum - Synaptic function" "Cluster 1: Neurons - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" "unprognostic (2.53e-2)" "unprognostic (1.22e-1)" "unprognostic (3.63e-1)" "unprognostic (1.21e-1)" "unprognostic (1.82e-1)" "unprognostic (9.67e-2)" "unprognostic (1.23e-1)" "unprognostic (1.49e-1)" "unprognostic (2.12e-1)" "unprognostic (4.91e-2)" "unprognostic (1.53e-1)" "unprognostic (8.04e-2)" "unprognostic (3.87e-3)" "unprognostic (1.79e-1)" "unprognostic (6.28e-2)" "unprognostic (2.48e-2)" "unprognostic (2.82e-1)" "unprognostic (2.99e-1)" "unprognostic (1.51e-2)" "unprognostic (4.40e-2)" "unprognostic (7.29e-2)" "unprognostic (1.59e-2)" "unprognostic (1.51e-1)" "unprognostic (8.39e-2)" "unprognostic (1.27e-1)" "unprognostic (1.71e-2)" "unprognostic (8.82e-2)" "unprognostic (2.95e-1)" "unprognostic (8.87e-2)" "unprognostic (3.95e-2)" "unprognostic (5.51e-3)" ATP6V1A "ATP6A1, ATP6V1A1, VA68, Vma1, VPP2" ENSG00000114573 "ATPase H+ transporting V1 subunit A" P38606 3 113746770-113812056 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" Translocase "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 758.7;Epididymal clear cells: 516.5;Late spermatids: 1351.5;Neutrophils: 680.2;Renal collecting duct intercalated cells: 463.0;Respiratory ionocytes: 612.2;Salivary ionocytes: 487.5" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 5 "Kidney Chromophobe (TCGA): 228.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 78.5" "Group enriched" "Detected in all" 6 "dendritic cells: 36.2;granulocytes: 78.5;monocytes: 34.8" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Spleen - Macrophages, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006910, HPA035084" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA 1000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 36: Brain & Liver - Signaling" "Cluster 24: Neurons - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 62 "Vesicles, Cytosol" Nucleoplasm "CAB006910: , HPA035084: " "unprognostic (1.53e-1)" "unprognostic (8.63e-2)" "unprognostic (2.41e-3)" "unprognostic (2.31e-1)" "unprognostic (1.72e-2)" "unprognostic (1.49e-2)" "unprognostic (1.13e-1)" "unprognostic (2.26e-1)" "unprognostic (1.70e-1)" "unprognostic (2.43e-3)" "potential prognostic favorable (3.52e-10)" "unprognostic (1.26e-1)" "unprognostic (7.06e-2)" "unprognostic (3.94e-2)" "unprognostic (2.67e-2)" "unprognostic (2.32e-1)" "unprognostic (1.60e-1)" "unprognostic (3.77e-2)" "unprognostic (1.17e-1)" "unprognostic (1.59e-1)" "unprognostic (4.48e-3)" "unprognostic (8.21e-3)" "unprognostic (1.70e-1)" "unprognostic (3.54e-2)" "unprognostic (1.10e-1)" "unprognostic (2.77e-1)" "unprognostic (8.44e-2)" "unprognostic (3.35e-1)" "unprognostic (1.50e-1)" "unprognostic (2.70e-1)" "unprognostic (2.67e-1)" ATP6V1B1 "ATP6B1, RTA1B, VATB, Vma2, VPP3" ENSG00000116039 "ATPase H+ transporting V1 subunit B1" P15313 2 70935900-70965431 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "kidney: 128.7;salivary gland: 131.8" "Cell type enhanced" "Detected in some" "Conjunctival goblet cells: 65.0;Cytotrophoblasts: 42.2;Epididymal clear cells: 167.4;Fallopian secretory cells: 16.3;Migrating cytotrophoblasts: 24.1;Renal collecting duct intercalated cells: 28.1;Salivary basal cells: 19.1;Salivary duct cells: 87.7;Salivary ionocytes: 44.5" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 15 "Kidney Chromophobe (TCGA): 522.6;Ovary Serous Cystadenocarcinoma (TCGA): 171.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 14.7;ovarian cancer: 9.8" "Breast - Breast glandular cells (progenitors), Kidney - Intercalated cells, Minor Salivary Gland - Minor salivary gland ductal cells, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB009523, HPA031847" Enhanced Approved "Nucleoplasm,Nuclear membrane" No NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 37: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 43 "Nucleoplasm, Nuclear membrane" "CAB009523: , HPA031847: " "unprognostic (8.00e-2)" "unprognostic (5.16e-2)" "unprognostic (1.62e-1)" "unprognostic (1.55e-1)" "unprognostic (2.26e-1)" "unprognostic (1.02e-1)" "unprognostic (2.77e-2)" "unprognostic (8.48e-2)" "unprognostic (6.98e-2)" "unprognostic (3.67e-2)" "unprognostic (1.59e-1)" "unprognostic (2.00e-1)" "unprognostic (1.90e-2)" "unprognostic (2.03e-2)" "unprognostic (1.39e-1)" "unprognostic (3.78e-1)" "unprognostic (1.18e-1)" "unprognostic (7.56e-3)" "unprognostic (1.58e-2)" "unprognostic (2.07e-1)" "unprognostic (2.76e-2)" "unprognostic (2.76e-2)" "unprognostic (1.62e-1)" "unprognostic (2.94e-1)" ATP6V1B2 "ATP6B2, HO57, VATB, Vma2, VPP3" ENSG00000147416 "ATPase H+ transporting V1 subunit B2" P21281 8 20197381-20226819 "Disease related genes, Essential proteins, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Deafness, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Kupffer cells: 198.8;monocytes: 270.2;Neutrophils: 523.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1134.2" "Group enriched" "Detected in all" 10 "dendritic cells: 336.8;granulocytes: 1134.2;monocytes: 682.6" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Prostate - Macrophages, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008147 Enhanced Supported Vesicles NA NA 220000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 40: Non-specific - Unknown function" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 94 Vesicles "HPA008147: " "unprognostic (1.91e-3)" "unprognostic (1.04e-1)" "unprognostic (3.22e-3)" "unprognostic (8.28e-2)" "unprognostic (1.37e-2)" "unprognostic (6.69e-2)" "unprognostic (2.60e-3)" "unprognostic (1.55e-2)" "unprognostic (3.37e-2)" "unprognostic (3.54e-2)" "potential prognostic favorable (1.29e-7)" "unprognostic (1.56e-3)" "potential prognostic favorable (3.73e-4)" "potential prognostic unfavorable (5.23e-4)" "unprognostic (2.00e-1)" "unprognostic (2.39e-2)" "unprognostic (9.31e-3)" "unprognostic (1.66e-1)" "unprognostic (1.22e-1)" "unprognostic (1.33e-3)" "unprognostic (6.08e-3)" "unprognostic (4.85e-3)" "unprognostic (1.95e-1)" "unprognostic (8.60e-2)" "unprognostic (4.95e-2)" "unprognostic (5.84e-3)" "unprognostic (7.50e-2)" "unprognostic (1.50e-1)" "unprognostic (6.84e-2)" "unprognostic (1.01e-1)" "unprognostic (2.37e-1)" ATP6V1C1 "ATP6C, ATP6D, VATC, Vma5" ENSG00000155097 "ATPase H+ transporting V1 subunit C1" P21283 8 103021063-103073051 "Essential proteins, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 279.2;Neutrophils: 539.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023943, HPA057297" Approved Approved Nucleoplasm,Cytosol NA NA 13000 "Cluster 40: Monocytes - Innate immune response" "Cluster 36: Brain & Liver - Signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 40: Non-specific - Unknown function" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 42 Nucleoplasm Cytosol "HPA023943: , HPA057297: " "unprognostic (1.07e-1)" "unprognostic (1.70e-3)" "unprognostic (1.13e-1)" "unprognostic (4.59e-3)" "unprognostic (1.08e-1)" "unprognostic (3.19e-1)" "unprognostic (1.54e-2)" "unprognostic (1.06e-1)" "potential prognostic unfavorable (8.98e-4)" "potential prognostic unfavorable (3.07e-6)" "potential prognostic favorable (1.86e-7)" "unprognostic (1.28e-3)" "unprognostic (1.09e-1)" "potential prognostic unfavorable (1.07e-4)" "unprognostic (7.57e-3)" "unprognostic (2.36e-3)" "unprognostic (1.37e-1)" "unprognostic (1.02e-1)" "unprognostic (6.42e-3)" "unprognostic (3.98e-3)" "unprognostic (1.10e-2)" "unprognostic (1.58e-2)" "potential prognostic unfavorable (3.03e-5)" "unprognostic (6.75e-3)" "unprognostic (1.90e-1)" "unprognostic (1.43e-1)" "unprognostic (2.58e-1)" "unprognostic (1.57e-1)" "unprognostic (3.98e-1)" "unprognostic (1.75e-1)" "unprognostic (1.68e-1)" ATP6V1C2 "ATP6C2, VMA5" ENSG00000143882 "ATPase H+ transporting V1 subunit C2" Q8NEY4 2 10721100-10785110 "Metabolic proteins, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 75.8;salivary gland: 97.2;skin 1: 82.8" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 179.6;Cytotrophoblasts: 240.5;Endometrial glandular cells: 251.1;Epididymal clear cells: 251.1;Esophageal apical cells: 158.2;Migrating cytotrophoblasts: 157.6;Renal collecting duct intercalated cells: 593.9;Respiratory ionocytes: 261.6;Salivary basal cells: 144.8;Salivary duct cells: 744.6;Salivary ionocytes: 589.5;Syncytiotrophoblasts: 237.6" "Cell type enhanced" "Detected in many" "hippocampal CA1-3: 20.9;miscellaneous: 30.4" "Group enriched" "Detected in many" 10 "Kidney Chromophobe (TCGA): 53.9;Prostate Adenocarcinoma (TCGA): 61.9;Uterine Corpus Endometrial Carcinoma (TCGA): 115.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Kidney - Intercalated cells, Minor Salivary Gland - Minor salivary gland ductal cells, Pituitary gland - Corticotropes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA034734, HPA067305" Approved Uncertain Mitochondria NA NA "Cluster 58: Skin - Keratinization" "Cluster 34: Non-specific - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 25 Mitochondria "HPA034734: , HPA067305: " "unprognostic (1.48e-1)" "unprognostic (1.42e-1)" "unprognostic (1.25e-2)" "unprognostic (2.27e-1)" "unprognostic (6.55e-3)" "unprognostic (3.82e-3)" "unprognostic (4.85e-2)" "unprognostic (3.82e-2)" "unprognostic (5.89e-2)" "potential prognostic unfavorable (2.74e-10)" "unprognostic (6.82e-3)" "unprognostic (4.55e-3)" "potential prognostic unfavorable (5.40e-7)" "unprognostic (1.55e-1)" "unprognostic (1.80e-1)" "unprognostic (6.16e-2)" "unprognostic (5.96e-2)" "unprognostic (7.14e-2)" "unprognostic (2.87e-3)" "unprognostic (2.53e-2)" "unprognostic (2.76e-3)" "unprognostic (2.68e-1)" "unprognostic (7.26e-2)" "unprognostic (5.85e-2)" "unprognostic (3.08e-1)" "unprognostic (7.91e-2)" "unprognostic (5.56e-2)" "unprognostic (4.22e-2)" "unprognostic (3.16e-1)" ATP6V1D "ATP6M, VATD, VMA8" ENSG00000100554 "ATPase H+ transporting V1 subunit D" Q9Y5K8 14 67294371-67360265 "Essential proteins, Metabolic proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation, Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Esophageal apical cells: 1788.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031515, HPA057316" Enhanced Approved "Nucleoplasm,Plasma membrane" NA No 11000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 76: Non-specific - Metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 63 "Plasma membrane" Nucleoplasm "HPA031515: , HPA057316: " "unprognostic (1.28e-1)" "unprognostic (4.04e-2)" "unprognostic (7.77e-2)" "unprognostic (8.70e-3)" "unprognostic (2.21e-1)" "unprognostic (3.79e-2)" "unprognostic (2.11e-1)" "unprognostic (2.41e-1)" "unprognostic (8.49e-3)" "unprognostic (2.19e-3)" "potential prognostic favorable (5.58e-9)" "unprognostic (1.81e-3)" "potential prognostic favorable (2.39e-4)" "unprognostic (8.45e-3)" "unprognostic (1.45e-2)" "unprognostic (4.30e-3)" "unprognostic (1.04e-1)" "unprognostic (1.17e-1)" "unprognostic (4.59e-2)" "unprognostic (1.05e-1)" "unprognostic (3.39e-3)" "unprognostic (7.33e-2)" "potential prognostic unfavorable (7.58e-4)" "unprognostic (1.03e-1)" "unprognostic (1.95e-1)" "unprognostic (1.08e-1)" "unprognostic (1.83e-1)" "unprognostic (1.33e-1)" "unprognostic (5.14e-1)" "unprognostic (1.47e-1)" "unprognostic (2.25e-2)" ATP6V1E1 "ATP6E, ATP6E2, ATP6V1E, P31, Vma4" ENSG00000131100 "ATPase H+ transporting V1 subunit E1" P36543 22 17592136-17628749 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 595.4;Syncytiotrophoblasts: 637.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Not detected" "Not detected" "CAB009528, CAB018699, HPA029196" Enhanced NA NA 29000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 66: Non-specific - Mitochondria" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 54 "CAB009528: , CAB018699: , HPA029196: " "unprognostic (1.79e-2)" "potential prognostic unfavorable (2.94e-4)" "unprognostic (1.52e-2)" "unprognostic (2.47e-3)" "unprognostic (1.93e-1)" "unprognostic (1.49e-1)" "unprognostic (3.43e-1)" "unprognostic (3.45e-1)" "unprognostic (2.55e-3)" "unprognostic (3.01e-1)" "validated prognostic favorable (2.52e-8)" "validated prognostic favorable (7.40e-4)" "potential prognostic favorable (6.69e-5)" "potential prognostic unfavorable (4.86e-6)" "unprognostic (2.37e-3)" "unprognostic (7.07e-2)" "unprognostic (4.02e-1)" "unprognostic (1.81e-2)" "unprognostic (2.43e-1)" "unprognostic (1.64e-1)" "unprognostic (9.88e-2)" "unprognostic (5.17e-3)" "unprognostic (2.56e-2)" "unprognostic (5.83e-2)" "unprognostic (1.02e-1)" "unprognostic (2.16e-2)" "unprognostic (1.01e-1)" "unprognostic (5.80e-2)" "unprognostic (1.88e-1)" "unprognostic (4.63e-2)" "unprognostic (2.25e-2)" ATP6V1E2 "ATP6E1, ATP6EL2, ATP6V1EL2, MGC9341, VMA4" ENSG00000250565 "ATPase H+ transporting V1 subunit E2" Q96A05 2 46490750-46542577 "Metabolic proteins, Predicted intracellular proteins" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "testis: 27.0" "Group enriched" "Detected in many" 4 "Early spermatids: 448.6;Late primary spermatocytes: 324.6;Late spermatids: 344.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA075092 Enhanced NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 67: Testis - Mixed function" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 19 "HPA075092: " "unprognostic (1.20e-2)" "unprognostic (3.12e-1)" "unprognostic (8.11e-2)" "unprognostic (3.41e-1)" "unprognostic (2.09e-1)" "unprognostic (1.43e-1)" "unprognostic (1.72e-1)" "unprognostic (3.88e-2)" "unprognostic (5.72e-2)" "potential prognostic unfavorable (9.33e-4)" "unprognostic (1.91e-2)" "unprognostic (9.15e-2)" "unprognostic (6.30e-2)" "unprognostic (2.32e-3)" "unprognostic (1.24e-1)" "unprognostic (1.79e-2)" "unprognostic (2.66e-2)" "unprognostic (1.00e-1)" "unprognostic (7.91e-2)" "unprognostic (3.95e-2)" "unprognostic (2.69e-1)" "unprognostic (1.51e-1)" "unprognostic (1.12e-1)" "unprognostic (1.16e-1)" "unprognostic (1.19e-1)" "unprognostic (7.67e-2)" "unprognostic (4.42e-2)" "unprognostic (2.13e-1)" "unprognostic (2.46e-1)" "unprognostic (8.77e-3)" "unprognostic (1.11e-1)" ATP6V1F "ATP6S14, VATF, Vma7" ENSG00000128524 "ATPase H+ transporting V1 subunit F" Q16864 7 128862856-128865847 "Essential proteins, Metabolic proteins, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 1063.2;Esophageal suprabasal cells: 1029.7;Hofbauer cells: 1268.8;Late primary spermatocytes: 932.5;Late spermatids: 1415.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Lung - Macrophages, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009529, HPA048700, HPA062011" Supported NA NA 19000 "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 39: Non-specific - Transcription" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 64 "CAB009529: , HPA048700: , HPA062011: " "unprognostic (1.25e-1)" "unprognostic (1.98e-1)" "unprognostic (1.38e-2)" "unprognostic (3.05e-1)" "unprognostic (2.33e-2)" "unprognostic (2.80e-2)" "unprognostic (4.28e-3)" "unprognostic (7.97e-2)" "unprognostic (5.17e-3)" "unprognostic (2.75e-3)" "unprognostic (1.02e-2)" "unprognostic (1.82e-2)" "unprognostic (1.62e-3)" "validated prognostic unfavorable (7.52e-5)" "validated prognostic unfavorable (3.97e-4)" "unprognostic (9.06e-2)" "unprognostic (7.47e-2)" "unprognostic (3.13e-3)" "unprognostic (8.22e-2)" "unprognostic (1.28e-2)" "unprognostic (7.35e-2)" "unprognostic (3.15e-1)" "unprognostic (1.07e-1)" "unprognostic (1.26e-1)" "unprognostic (1.04e-2)" "unprognostic (5.88e-2)" "unprognostic (2.52e-2)" "unprognostic (1.66e-1)" "unprognostic (1.61e-1)" "unprognostic (2.45e-1)" "unprognostic (8.70e-2)" ATP6V1FNB ENSG00000272899 "ATP6V1F neighbor" A0A1B0GUX0 7 128866330-128872047 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 22.8;kidney: 12.3;skeletal muscle: 10.3" "Cell type enhanced" "Detected in some" "Early spermatids: 430.2;Late primary spermatocytes: 99.7;Late spermatids: 257.3" "Cell type enhanced" "Detected in many" "upper rhombic lip: 4.4" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 7.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 15: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" "unprognostic (7.14e-2)" "unprognostic (3.47e-2)" "potential prognostic favorable (1.73e-4)" "unprognostic (1.25e-1)" "potential prognostic favorable (1.07e-5)" "unprognostic (2.19e-1)" "potential prognostic unfavorable (1.24e-5)" "unprognostic (9.63e-2)" "unprognostic (2.80e-2)" "unprognostic (2.68e-2)" "unprognostic (2.57e-2)" "unprognostic (9.32e-2)" "unprognostic (4.00e-1)" "potential prognostic unfavorable (3.83e-4)" ATP6V1G1 "ATP6G, ATP6G1, ATP6GL, ATP6J, DKFZp547P234, Vma10" ENSG00000136888 "ATPase H+ transporting V1 subunit G1" O75348 9 114587706-114598915 "Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 2351.5;Gastric chief cells: 1089.9;Parietal cells: 1295.9;Syncytiotrophoblasts: 1074.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Prostate glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004615, HPA042898" Supported Approved Nucleoplasm,Nucleoli NA NA 100000 "Cluster 22: Eosinophils - Transcription" "Cluster 76: Non-specific - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 97: Non-specific - Cellular respiration" 61 Nucleoli Nucleoplasm "CAB004615: , HPA042898: " "unprognostic (1.09e-1)" "unprognostic (5.69e-2)" "unprognostic (8.97e-2)" "unprognostic (5.75e-2)" "unprognostic (1.75e-1)" "unprognostic (2.10e-2)" "unprognostic (2.95e-2)" "unprognostic (1.68e-1)" "unprognostic (1.39e-2)" "unprognostic (7.85e-2)" "potential prognostic favorable (6.20e-9)" "unprognostic (2.53e-2)" "unprognostic (8.46e-2)" "unprognostic (3.93e-2)" "unprognostic (3.77e-2)" "unprognostic (1.38e-1)" "unprognostic (1.72e-1)" "unprognostic (2.72e-1)" "unprognostic (7.14e-2)" "unprognostic (3.37e-1)" "unprognostic (1.34e-1)" "unprognostic (6.04e-2)" "unprognostic (9.14e-2)" "unprognostic (4.67e-2)" "unprognostic (1.97e-1)" "unprognostic (3.57e-1)" "unprognostic (3.43e-1)" "unprognostic (3.17e-1)" "unprognostic (2.78e-1)" "unprognostic (8.41e-2)" "unprognostic (1.20e-3)" ATP6V1G2 "ATP6G, ATP6G2, Em:AC004181.3, NG38, Vma10" ENSG00000213760 "ATPase H+ transporting V1 subunit G2" O95670 6 31544444-31548427 "Metabolic proteins, Predicted intracellular proteins" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 45 "brain: 578.2" "Cell type enhanced" "Detected in some" "Astrocytes: 9.3;Bergmann glia: 23.2;Brain excitatory neurons: 77.6;Brain inhibitory neurons: 36.0;Oligodendrocyte progenitor cells: 12.8;Oligodendrocytes: 11.2;Other brain neurons: 43.0" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in some" 4 "Glioblastoma Multiforme (TCGA): 12.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 5.2" "Adrenal gland - Adrenal medulla cells, Prostate - Fibroblasts, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004616, HPA068667" Enhanced NA NA "Cluster 24: Non-specific - Transcription" "Cluster 27: Cerebellum - Synaptic function" "Cluster 2: Neurons - Nucleosome" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 98: Neurons - Neurotransmission & signaling" 23 "CAB004616: , HPA068667: " "unprognostic (3.34e-1)" "unprognostic (4.44e-1)" "potential prognostic favorable (7.15e-4)" "unprognostic (6.88e-2)" "unprognostic (5.37e-2)" "unprognostic (1.99e-1)" ATP6V1G3 "ATP6G3, Vma10" ENSG00000151418 "ATPase H+ transporting V1 subunit G3" Q96LB4 1 198523222-198540945 "Metabolic proteins, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 33 "kidney: 65.6" "Cell type enhanced" "Detected in some" "Epididymal clear cells: 293.9;Renal collecting duct intercalated cells: 125.4;Respiratory ionocytes: 66.0" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 25 "Kidney Chromophobe (TCGA): 192.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Intercalated cells, Minor Salivary Gland - Minor salivary gland ductal cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA028701 Enhanced NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" "HPA028701: " "unprognostic (7.31e-2)" "unprognostic (5.29e-1)" ATP6V1H "CGI-11, SFD, SFDalpha, SFDbeta, VMA13" ENSG00000047249 "ATPase H+ transporting V1 subunit H" Q9UI12 8 53715543-53843558 "Essential proteins, Metabolic proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial glandular cells: 619.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Macrophages, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009532, HPA023421" Approved Supported "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 73: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 40: Non-specific - Unknown function" "Cluster 51: Secretory epithelial cells - Mixed function" 41 "Actin filaments, Cytosol" "Plasma membrane" "CAB009532: , HPA023421: " "unprognostic (1.66e-1)" "potential prognostic unfavorable (4.98e-5)" "unprognostic (1.29e-1)" "unprognostic (1.37e-1)" "unprognostic (3.61e-1)" "unprognostic (2.64e-2)" "unprognostic (6.97e-2)" "unprognostic (2.90e-2)" "unprognostic (5.49e-2)" "unprognostic (4.57e-2)" "potential prognostic favorable (6.52e-6)" "unprognostic (2.24e-1)" "unprognostic (6.67e-2)" "potential prognostic unfavorable (2.08e-4)" "unprognostic (2.78e-2)" "unprognostic (1.67e-1)" "unprognostic (2.87e-1)" "unprognostic (1.05e-1)" "unprognostic (5.68e-3)" "unprognostic (8.45e-2)" "unprognostic (1.45e-2)" "unprognostic (1.04e-1)" "unprognostic (6.94e-2)" "unprognostic (2.49e-1)" "unprognostic (2.96e-1)" "unprognostic (1.15e-1)" "unprognostic (1.92e-1)" "unprognostic (4.39e-2)" "unprognostic (4.00e-1)" "unprognostic (1.09e-1)" "unprognostic (2.28e-1)" ATP7A MNK ENSG00000165240 "ATPase copper transporting alpha" Q04656 X 77910690-78050395 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Copper transport, Ion transport, Transport" Translocase "Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Respiratory ionocytes: 20.3;Salivary ionocytes: 14.8" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 8.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Vascular endothelial cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012887, HPA048107" Approved Supported "Golgi apparatus" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 55: Breast - Lactation" "Cluster 11: White matter - Signal transduction" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 17: Non-specific - RNA processing" 9 "Golgi apparatus" "HPA012887: , HPA048107: " "unprognostic (4.34e-1)" "unprognostic (6.89e-2)" "unprognostic (3.61e-1)" "unprognostic (3.04e-1)" "unprognostic (2.23e-1)" "unprognostic (4.44e-3)" "unprognostic (1.83e-1)" "unprognostic (2.73e-1)" "unprognostic (9.52e-2)" "unprognostic (3.32e-2)" "potential prognostic favorable (8.04e-5)" "unprognostic (1.11e-3)" "unprognostic (7.54e-2)" "unprognostic (2.17e-3)" "unprognostic (1.71e-1)" "unprognostic (2.24e-1)" "unprognostic (2.82e-1)" "unprognostic (2.54e-2)" "unprognostic (2.99e-2)" "unprognostic (2.81e-1)" "potential prognostic unfavorable (1.26e-4)" "unprognostic (5.33e-3)" "unprognostic (1.05e-1)" "unprognostic (1.04e-1)" "unprognostic (8.74e-3)" "unprognostic (3.02e-3)" "unprognostic (3.85e-2)" "unprognostic (4.21e-1)" "unprognostic (1.55e-1)" "unprognostic (1.39e-1)" "unprognostic (7.38e-2)" ATP7B WND ENSG00000123191 "ATPase copper transporting beta" P35670 13 51930436-52012125 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Copper transport, Ion transport, Transport" Translocase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 10.0" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 64.2;Conjunctival goblet cells: 148.5;Early spermatids: 100.8;Late spermatids: 140.7;Mesothelial cells: 63.2;Salivary duct cells: 81.1;Salivary ionocytes: 82.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA009137, HPA013187" Supported Supported "Golgi apparatus" NA NA "Cluster 21: Testis - Mixed function" "Cluster 29: Forebrain - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 104: Brain endothelial cells - Blood brain barrier" 10 "Golgi apparatus" "HPA009137: , HPA013187: " "unprognostic (1.21e-2)" "unprognostic (1.21e-1)" "unprognostic (4.62e-2)" "unprognostic (5.74e-2)" "unprognostic (9.53e-2)" "unprognostic (2.97e-1)" "unprognostic (3.81e-2)" "unprognostic (1.76e-1)" "potential prognostic favorable (3.74e-10)" "unprognostic (1.62e-2)" "unprognostic (1.74e-1)" "unprognostic (3.16e-1)" "unprognostic (1.68e-2)" "unprognostic (2.26e-1)" "unprognostic (1.33e-3)" "unprognostic (8.77e-2)" "unprognostic (4.05e-2)" "unprognostic (1.20e-1)" "unprognostic (2.04e-1)" "unprognostic (3.13e-1)" "unprognostic (3.34e-1)" "unprognostic (2.00e-1)" "unprognostic (3.88e-2)" "unprognostic (4.34e-1)" "unprognostic (6.90e-2)" "unprognostic (4.67e-2)" "unprognostic (4.74e-1)" "unprognostic (2.09e-2)" ATP8A1 ATPIA ENSG00000124406 "ATPase phospholipid transporting 8A1" Q9Y2Q0 4 42408373-42657121 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 37.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 487.7;Brain inhibitory neurons: 488.4;Myonuclei: 700.5;Neutrophil progenitors: 709.7;Oligodendrocytes: 1233.4;Prostatic glandular cells: 484.1;Transitional alveolar cells: 621.5" "Cell type enhanced" "Detected in all" "oligodendrocyte: 1793.6" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 13.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "lymphoma: 17.2" "Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Skeletal muscle - Skeletal myocytes, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052935 Enhanced Approved Vesicles,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 5 Cytosol Vesicles "HPA052935: " "unprognostic (9.69e-2)" "unprognostic (5.09e-3)" "unprognostic (3.64e-2)" "unprognostic (1.65e-1)" "unprognostic (2.08e-1)" "unprognostic (2.42e-2)" "unprognostic (4.80e-2)" "potential prognostic favorable (1.17e-9)" "unprognostic (7.64e-3)" "unprognostic (1.44e-1)" "unprognostic (7.14e-2)" "potential prognostic favorable (1.65e-4)" "unprognostic (1.46e-1)" "unprognostic (2.74e-3)" "unprognostic (1.19e-1)" "unprognostic (4.06e-1)" "unprognostic (1.84e-1)" "unprognostic (6.05e-2)" "unprognostic (3.87e-2)" "potential prognostic favorable (1.11e-4)" "unprognostic (4.22e-1)" "unprognostic (1.08e-1)" "unprognostic (8.65e-2)" "unprognostic (4.21e-1)" "unprognostic (4.33e-2)" ATP8A2 "ATPIB, ML-1" ENSG00000132932 "ATPase phospholipid transporting 8A2" Q9NTI2 13 25371974-26025851 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Lipid transport, Transport" Translocase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 17.8;pituitary gland: 13.6;retina: 13.7" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 814.7;Brain inhibitory neurons: 644.7;Cone photoreceptor cells: 467.8;Corticotrophs: 656.6;Gonadotrophs: 1438.7;Lactotrophs: 936.6;Other brain neurons: 711.3;Retinal ganglion cells: 969.6;Rod photoreceptor cells: 961.6;Somatotrophs: 918.3;Thyrotrophs: 1198.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "prostate cancer: 5.2" "Colon - Colon enteroendocrine cells, Skin - Outer root sheath cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039926, HPA040033" Enhanced Supported "Nucleoplasm,Plasma membrane,Acrosome,Mid piece,Annulus" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 24: Non-specific - Unknown function" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 1 "Plasma membrane" "Nucleoplasm, Acrosome, Mid piece, Annulus" "HPA039926: , HPA040033: " "unprognostic (3.12e-2)" "unprognostic (1.99e-1)" "unprognostic (4.28e-2)" "unprognostic (2.34e-1)" "unprognostic (1.50e-1)" "unprognostic (1.37e-1)" ATP8B1 "ATPIC, BRIC, FIC1, PFIC, PFIC1" ENSG00000081923 "ATPase phospholipid transporting 8B1" O43520 18 57646426-57803315 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hearing, Lipid transport, Transport" Translocase "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 71.4" "Cell type enhanced" "Detected in many" "Foveolar cells: 566.4;Prostatic club cells: 660.3;Prostatic hillock cells: 589.2;Urothelial cells: 1235.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skeletal muscle - Fibroblasts, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA018673, HPA018674" Enhanced Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 17: Intestine - Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 2 "Plasma membrane, Cytosol" "Nucleoplasm, Nuclear bodies" "HPA018673: , HPA018674: " "unprognostic (1.79e-1)" "unprognostic (9.13e-2)" "unprognostic (7.27e-2)" "unprognostic (4.08e-2)" "potential prognostic favorable (8.40e-4)" "unprognostic (1.06e-3)" "unprognostic (1.20e-1)" "unprognostic (1.94e-3)" "unprognostic (2.70e-1)" "unprognostic (2.81e-1)" "validated prognostic favorable (4.75e-4)" "validated prognostic favorable (7.06e-6)" "unprognostic (1.41e-1)" "unprognostic (1.90e-1)" "unprognostic (3.14e-3)" "unprognostic (3.44e-2)" "unprognostic (7.25e-2)" "unprognostic (1.71e-1)" "unprognostic (9.68e-2)" "unprognostic (1.66e-1)" "unprognostic (7.26e-2)" "unprognostic (6.87e-3)" "unprognostic (3.91e-1)" "unprognostic (1.18e-1)" "unprognostic (1.36e-2)" "unprognostic (4.13e-3)" "unprognostic (1.60e-1)" "unprognostic (2.49e-1)" "unprognostic (3.57e-1)" "unprognostic (1.36e-1)" "unprognostic (8.64e-2)" ATP8B2 "ATPID, KIAA1137" ENSG00000143515 "ATPase phospholipid transporting 8B2" P98198 1 154325525-154351304 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 56.0;Plasma cells: 51.3;Sertoli cells: 113.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 4.9" "Group enriched" "Detected in many" 6 "granulocytes: 2.7;T-cells: 4.9" "Cancer enhanced" "Detected in all" "Myeloma: 105.7" "Adipose visceral - Adipose progenitor cells, Adrenal gland - Fibroblasts, Breast - Fibroblasts, Prostate - Smooth muscle cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046680, HPA061103" Approved Supported "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 9: T-cells - Adaptive immunity: Regulation" 3 "Plasma membrane" "Nucleoli, Cytosol" "HPA046680: , HPA061103: " "unprognostic (1.46e-1)" "unprognostic (1.30e-1)" "unprognostic (2.50e-1)" "unprognostic (2.09e-2)" "unprognostic (2.56e-2)" "unprognostic (7.23e-2)" "unprognostic (4.83e-1)" "potential prognostic favorable (8.02e-4)" "unprognostic (7.29e-2)" "unprognostic (3.84e-2)" "unprognostic (4.38e-2)" "unprognostic (8.30e-3)" "unprognostic (2.24e-3)" "unprognostic (1.08e-2)" "unprognostic (7.41e-2)" "unprognostic (1.81e-3)" "unprognostic (5.27e-2)" "unprognostic (1.00e-1)" "unprognostic (9.30e-2)" "unprognostic (6.64e-2)" "unprognostic (2.16e-1)" "unprognostic (2.99e-3)" "unprognostic (2.03e-1)" "unprognostic (1.91e-1)" "unprognostic (1.27e-1)" "unprognostic (4.62e-2)" "unprognostic (2.42e-1)" "unprognostic (5.68e-3)" "unprognostic (2.50e-1)" "unprognostic (4.05e-2)" "unprognostic (1.05e-1)" ATP8B3 ATPIK ENSG00000130270 "ATPase phospholipid transporting 8B3" O60423 19 1782075-1812276 "Enzymes, Predicted membrane proteins" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 5.5;testis: 20.6" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 14.8;Early spermatids: 10.2;Late primary spermatocytes: 31.9;Late spermatids: 21.9;Monocyte progenitors: 18.7;Neutrophil progenitors: 10.9" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 3.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 39: Testis - Nuclear processes" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 27: Non-specific - Cell proliferation" "unprognostic (1.96e-1)" "unprognostic (2.38e-3)" "unprognostic (7.29e-3)" "unprognostic (7.00e-2)" "unprognostic (8.89e-2)" "potential prognostic unfavorable (5.85e-5)" "unprognostic (6.50e-3)" "unprognostic (1.36e-2)" "unprognostic (7.24e-3)" "potential prognostic unfavorable (8.63e-4)" "unprognostic (5.75e-2)" "unprognostic (2.62e-1)" ATP8B4 "ATPIM, KIAA1939" ENSG00000104043 "ATPase phospholipid transporting 8B4 (putative)" Q8TF62 15 49858238-50182817 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "bone marrow: 73.7" "Cell type enhanced" "Detected in many" "Hematopoietic stem cells: 1510.5;Innate lymphoid cells: 435.5;Macrophages: 376.2;Mast cells: 418.8;Microglia: 1156.7;Monocyte progenitors: 788.5;Neutrophil progenitors: 3655.2;Neutrophils: 370.4;NK-cells: 386.7;Thymocytes: 525.1" "Cell type enriched" "Detected in many" 9 "central nervous system macrophage: 1465.9" "Cancer enhanced" "Detected in some" "Prostate Adenocarcinoma (TCGA): 2.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 15.3;NK-cell: 11.0" "Group enriched" "Detected in many" 5 "granulocytes: 15.3;NK-cells: 11.0" "Cancer enriched" "Detected in some" 6 "Leukemia: 14.8" "Adrenal gland - Macrophages, Skin - Endothelial cells, Spleen - Neutrophils_1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA040254 Approved Uncertain Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 41: Basophils - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 29: Forebrain - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 2 "Nucleoplasm, Vesicles" Cytosol "HPA040254: " "unprognostic (9.75e-2)" "unprognostic (3.17e-1)" "unprognostic (2.31e-2)" "unprognostic (1.98e-2)" "unprognostic (1.70e-3)" "unprognostic (5.36e-3)" "unprognostic (1.47e-2)" "unprognostic (3.09e-1)" "unprognostic (4.68e-2)" "unprognostic (3.98e-1)" "unprognostic (1.27e-3)" "unprognostic (1.42e-1)" ATP9A "ATPIIA, KIAA0611" ENSG00000054793 "ATPase phospholipid transporting 9A (putative)" O75110 20 51596514-51768390 "Enzymes, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 87.5" "Cell type enhanced" "Detected in many" "Urothelial cells: 286.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "basophil: 4.4" "Lineage enriched" "Detected in many" 4 "granulocytes: 4.4" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Pituitary gland - Lactotropes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020699, HPA035630" Enhanced NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 73: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 40: Non-specific - Unknown function" "Cluster 51: Secretory epithelial cells - Mixed function" 9 "CAB020699: , HPA035630: " "unprognostic (5.37e-3)" "unprognostic (1.08e-1)" "unprognostic (2.01e-1)" "unprognostic (3.10e-2)" "unprognostic (2.97e-1)" "unprognostic (1.68e-1)" "unprognostic (4.02e-1)" "unprognostic (4.36e-2)" "unprognostic (3.94e-1)" "unprognostic (1.31e-1)" "unprognostic (1.52e-3)" "unprognostic (3.88e-2)" "unprognostic (3.16e-1)" "unprognostic (3.06e-2)" "unprognostic (7.54e-3)" "unprognostic (4.24e-2)" "unprognostic (1.92e-2)" "unprognostic (1.43e-3)" "unprognostic (1.79e-2)" "unprognostic (8.54e-3)" "potential prognostic unfavorable (1.60e-4)" "unprognostic (1.63e-2)" "unprognostic (2.54e-1)" "unprognostic (2.49e-1)" "unprognostic (3.30e-3)" "unprognostic (1.20e-1)" "unprognostic (2.65e-2)" "unprognostic (4.66e-2)" "unprognostic (2.16e-1)" "unprognostic (7.77e-2)" "unprognostic (1.54e-2)" ATP9B ATPIIB ENSG00000166377 "ATPase phospholipid transporting 9B (putative)" O43861 18 79069285-79378287 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029364 Approved NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 40: Non-specific - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 56: Non-specific - Sensory perception" "Cluster 7: Non-specific - Transcription" "HPA029364: " "unprognostic (2.12e-1)" "unprognostic (8.90e-2)" "unprognostic (1.69e-1)" "unprognostic (3.39e-2)" "unprognostic (8.09e-3)" "unprognostic (6.95e-2)" "unprognostic (8.10e-2)" "unprognostic (6.17e-3)" "unprognostic (6.19e-2)" "unprognostic (3.29e-3)" "unprognostic (2.71e-2)" "potential prognostic favorable (9.74e-4)" "unprognostic (8.77e-2)" "unprognostic (1.29e-1)" "unprognostic (3.24e-2)" "unprognostic (3.95e-1)" "unprognostic (2.58e-1)" "unprognostic (2.34e-2)" "unprognostic (1.28e-1)" "unprognostic (2.71e-1)" "unprognostic (1.48e-1)" "unprognostic (2.65e-2)" "unprognostic (6.80e-3)" "unprognostic (1.99e-1)" "unprognostic (6.92e-2)" "unprognostic (8.39e-2)" "unprognostic (1.33e-1)" "unprognostic (2.77e-2)" "unprognostic (1.63e-1)" "unprognostic (9.16e-3)" "unprognostic (1.60e-2)" ATPAF1 "ATP11, Atp11p, FLJ22351" ENSG00000123472 "ATP synthase mitochondrial F1 complex assembly factor 1" Q5TC12 1 46632737-46673867 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 295.7" "Group enriched" "Detected in many" 4 "Early spermatids: 370.9;Late spermatids: 647.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028382, HPA044950" Approved Approved Mitochondria NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 37: Non-specific - mRNA processing" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 16 Mitochondria "HPA028382: , HPA044950: " "unprognostic (2.50e-1)" "unprognostic (2.76e-1)" "unprognostic (9.21e-2)" "unprognostic (1.67e-1)" "unprognostic (5.72e-3)" "unprognostic (4.19e-2)" "unprognostic (1.38e-1)" "unprognostic (2.27e-1)" "unprognostic (3.30e-1)" "unprognostic (6.14e-2)" "potential prognostic favorable (9.43e-6)" "unprognostic (7.50e-3)" "potential prognostic favorable (7.89e-4)" "unprognostic (2.75e-1)" "unprognostic (2.27e-1)" "unprognostic (4.90e-2)" "unprognostic (2.26e-1)" "unprognostic (2.16e-1)" "unprognostic (2.36e-1)" "unprognostic (1.66e-2)" "unprognostic (5.25e-1)" "unprognostic (1.69e-1)" "unprognostic (1.46e-1)" "unprognostic (2.16e-1)" "unprognostic (1.42e-2)" "unprognostic (2.40e-1)" "unprognostic (1.64e-2)" "unprognostic (2.73e-1)" "unprognostic (2.38e-1)" "unprognostic (2.54e-1)" "unprognostic (2.69e-2)" ATPAF2 "ATP12, Atp12p, LP3663, MGC29736" ENSG00000171953 "ATP synthase mitochondrial F1 complex assembly factor 2" Q8N5M1 17 17977409-18039209 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Chaperone "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 81.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "testis cancer: 96.0" "Heart muscle - Cardiomyocytes, Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023329, HPA059422" Supported Uncertain Cytosol No No "Cluster 10: Non-specific - Membrane trafficking" "Cluster 52: Non-specific - Cellular respiration" "Cluster 25: Non-specific - Transcription" "Cluster 42: Non-specific - Unknown function" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 78 Cytosol "HPA023329: , HPA059422: " "unprognostic (1.09e-1)" "unprognostic (2.49e-2)" "unprognostic (2.66e-1)" "unprognostic (2.60e-1)" "unprognostic (5.82e-2)" "unprognostic (9.80e-2)" "unprognostic (3.37e-1)" "potential prognostic favorable (3.02e-7)" "unprognostic (1.09e-1)" "unprognostic (6.15e-3)" "potential prognostic favorable (8.71e-7)" "unprognostic (1.84e-2)" "potential prognostic favorable (3.25e-4)" "unprognostic (6.33e-2)" "unprognostic (1.30e-1)" "unprognostic (1.44e-2)" "unprognostic (3.08e-2)" "unprognostic (2.68e-1)" "unprognostic (4.57e-1)" "unprognostic (2.17e-1)" "unprognostic (1.08e-1)" "unprognostic (4.83e-3)" "unprognostic (2.67e-3)" "unprognostic (5.75e-3)" "unprognostic (3.45e-2)" "unprognostic (1.95e-1)" "unprognostic (6.31e-2)" "unprognostic (2.58e-1)" "unprognostic (1.42e-1)" "unprognostic (1.24e-1)" "unprognostic (1.61e-1)" ATPSCKMT "FAM173B, JS-2" ENSG00000150756 "ATP synthase c subunit lysine N-methyltransferase" Q6P4H8 5 10225507-10249897 "Predicted intracellular proteins, Predicted membrane proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074513 Approved Nucleoplasm,Vesicles NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 73: Brain - Neuronal signaling" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 29: Non-specific - Unknown function" "Cluster 109: Neurons - Neuronal signaling" 3 "Nucleoplasm, Vesicles" "HPA074513: " "unprognostic (6.21e-2)" "potential prognostic unfavorable (1.37e-5)" "unprognostic (4.34e-2)" "unprognostic (1.35e-2)" "unprognostic (1.17e-2)" "unprognostic (1.67e-2)" "unprognostic (2.96e-1)" "unprognostic (5.05e-2)" "unprognostic (4.05e-1)" "potential prognostic favorable (6.34e-5)" "unprognostic (1.18e-1)" "unprognostic (2.34e-1)" "unprognostic (2.87e-2)" "unprognostic (2.22e-1)" "unprognostic (3.72e-2)" "unprognostic (2.51e-1)" "unprognostic (3.69e-2)" "unprognostic (9.47e-2)" "unprognostic (4.50e-2)" "unprognostic (7.76e-2)" "unprognostic (3.41e-1)" "unprognostic (4.60e-2)" "unprognostic (1.40e-3)" "unprognostic (1.15e-1)" "unprognostic (3.26e-2)" "unprognostic (2.21e-1)" "unprognostic (3.98e-1)" "unprognostic (2.42e-2)" "unprognostic (2.17e-1)" ATR "FRP1, MEC1, SCKL, SCKL1" ENSG00000175054 "ATR serine/threonine kinase" Q13535 3 142449007-142578733 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted membrane proteins" "DNA damage, DNA repair" "DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 373.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054320 Supported "Nucleoplasm,Golgi apparatus" No No "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 18: Adrenal cortex cells - Steroidogensis" 53 Nucleoplasm "Golgi apparatus" "HPA054320: " "unprognostic (8.65e-2)" "unprognostic (1.19e-1)" "unprognostic (1.73e-1)" "unprognostic (1.91e-2)" "unprognostic (1.87e-1)" "unprognostic (1.31e-1)" "unprognostic (1.43e-1)" "unprognostic (8.26e-2)" "unprognostic (1.96e-2)" "potential prognostic favorable (2.47e-5)" "unprognostic (6.13e-2)" "unprognostic (5.99e-2)" "unprognostic (3.09e-1)" "unprognostic (2.70e-1)" "unprognostic (1.98e-3)" "unprognostic (2.84e-1)" "unprognostic (3.14e-1)" "unprognostic (4.17e-2)" "potential prognostic unfavorable (4.00e-4)" "unprognostic (3.98e-2)" "unprognostic (3.02e-1)" "unprognostic (2.09e-2)" "unprognostic (1.10e-1)" "unprognostic (2.07e-1)" "unprognostic (1.24e-1)" "unprognostic (3.45e-1)" "unprognostic (1.24e-2)" "unprognostic (8.60e-2)" ATRAID "APR3, C2orf28, HSPC013, p18" ENSG00000138085 "All-trans retinoic acid induced differentiation factor" Q6UW56 2 27212041-27217178 "Predicted intracellular proteins, Predicted membrane proteins" Differentiation "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 412.8;Epididymal principal cells: 617.5;Extravillous trophoblasts: 439.8;Late primary spermatocytes: 463.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051353 Uncertain NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 22: Epididymis - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 8: Non-specific - Secretory pathway" 3 "HPA051353: " "unprognostic (4.98e-2)" "unprognostic (3.22e-1)" "unprognostic (5.07e-2)" "unprognostic (1.23e-1)" "unprognostic (1.94e-2)" "unprognostic (2.29e-2)" "unprognostic (8.55e-3)" "unprognostic (3.23e-2)" "unprognostic (3.62e-2)" "unprognostic (5.79e-2)" "unprognostic (3.75e-1)" "unprognostic (2.02e-2)" "unprognostic (1.20e-3)" "unprognostic (2.90e-1)" "unprognostic (1.39e-1)" "unprognostic (9.89e-2)" "unprognostic (1.98e-1)" "unprognostic (8.75e-3)" "unprognostic (1.61e-1)" "unprognostic (3.07e-1)" "unprognostic (4.18e-1)" "unprognostic (5.21e-2)" "unprognostic (2.10e-1)" "unprognostic (3.26e-1)" "unprognostic (2.79e-1)" "unprognostic (3.53e-3)" "unprognostic (2.15e-1)" "unprognostic (7.26e-2)" "unprognostic (5.32e-2)" ATRIP "FLJ12343, MGC20625, MGC21482, MGC26740" ENSG00000164053 "ATR interacting protein" Q8WXE1 3 48446710-48467645 "Essential proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 43.4;Late primary spermatocytes: 68.4;Late spermatids: 53.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033109, HPA047590" Approved Supported Nucleoplasm NA NA "Cluster 39: Testis - Nuclear processes" "Cluster 15: Non-specific - Transcription" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 65: Non-specific - Cell growth & division" 39 Nucleoplasm "CAB033109: , HPA047590: " "unprognostic (2.62e-1)" "unprognostic (2.48e-1)" "unprognostic (1.71e-1)" "unprognostic (1.21e-2)" "unprognostic (8.96e-2)" "unprognostic (2.38e-1)" "unprognostic (1.91e-1)" "unprognostic (2.56e-2)" "unprognostic (9.03e-3)" "unprognostic (8.10e-3)" "potential prognostic favorable (6.03e-5)" "unprognostic (1.20e-2)" "unprognostic (4.43e-2)" "potential prognostic unfavorable (7.15e-5)" "unprognostic (7.40e-2)" "unprognostic (4.37e-2)" "unprognostic (2.68e-1)" "unprognostic (4.07e-2)" "unprognostic (6.30e-2)" "unprognostic (2.74e-1)" "unprognostic (4.25e-3)" "unprognostic (1.76e-1)" "unprognostic (1.64e-2)" "unprognostic (1.08e-2)" "unprognostic (5.55e-2)" "unprognostic (2.02e-1)" "unprognostic (1.64e-1)" "unprognostic (3.70e-1)" "unprognostic (3.38e-3)" "unprognostic (8.46e-2)" ATRN "DPPT-L, MGCA" ENSG00000088812 Attractin O75882 20 3471018-3651118 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Inflammatory response" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 327.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008853 Approved Approved Cytosol "Secreted to blood" Receptor NA NA 6000000000 "Cluster 22: Eosinophils - Transcription" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 5 Cytosol "HPA008853: " "unprognostic (1.30e-1)" "unprognostic (6.80e-2)" "unprognostic (1.54e-1)" "unprognostic (6.98e-2)" "unprognostic (4.38e-2)" "unprognostic (2.42e-1)" "unprognostic (2.40e-1)" "unprognostic (2.35e-3)" "unprognostic (4.97e-2)" "unprognostic (1.85e-3)" "potential prognostic favorable (3.10e-6)" "unprognostic (2.14e-2)" "unprognostic (7.74e-2)" "unprognostic (2.43e-1)" "unprognostic (3.77e-1)" "unprognostic (1.78e-1)" "unprognostic (4.05e-1)" "unprognostic (5.11e-3)" "unprognostic (9.03e-2)" "unprognostic (2.66e-2)" "unprognostic (3.64e-3)" "unprognostic (2.91e-2)" "unprognostic (1.52e-1)" "unprognostic (4.91e-1)" "unprognostic (2.79e-1)" "unprognostic (1.33e-2)" "unprognostic (2.71e-1)" "unprognostic (4.83e-2)" "unprognostic (7.19e-2)" "unprognostic (1.62e-1)" "unprognostic (1.89e-1)" ATRNL1 "ALP, FLJ45344, KIAA0534" ENSG00000107518 "Attractin like 1" Q5VV63 10 115093365-115948999 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.2" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 1637.9;Brain excitatory neurons: 907.1;Brain inhibitory neurons: 810.0;Choroid plexus epithelial cells: 536.8;Granulosa cells: 403.1;Lactotrophs: 544.3;Oligodendrocyte progenitor cells: 1822.8;Retinal amacrine cells: 1202.8;Retinal bipolar cells: 907.9;Retinal ganglion cells: 733.9;Somatotrophs: 790.4;Thyrotrophs: 458.5" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 5.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Kidney - Fibroblasts, Prostate - Fibroblasts, Testis - Early spermatids, Testis - Spermatocytes, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038070 Approved Nucleoplasm,Mitochondria NA NA 13000000 "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" "Nucleoplasm, Mitochondria" "HPA038070: " "unprognostic (3.15e-2)" "unprognostic (2.83e-1)" "unprognostic (1.04e-1)" "potential prognostic favorable (1.56e-4)" "unprognostic (9.84e-2)" "unprognostic (4.14e-1)" "unprognostic (4.94e-2)" "unprognostic (2.37e-1)" "unprognostic (3.76e-2)" "unprognostic (1.37e-1)" "unprognostic (1.10e-1)" "unprognostic (8.80e-3)" ATRX "JMS, MRX52, RAD54, XH2, XNP" ENSG00000085224 "ATRX chromatin remodeler" P46100 X 77504880-77786233 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "DNA damage, DNA repair, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001906, CAB009372, HPA064684, CAB068176" Supported Supported "Nuclear bodies" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 36: Non-specific - mRNA processing" "Cluster 7: Non-specific - Transcription" 54 "Nuclear bodies" "CAB009372: , CAB068176: , HPA001906: , HPA064684: " "unprognostic (2.13e-3)" "unprognostic (4.60e-3)" "unprognostic (1.83e-1)" "unprognostic (1.56e-1)" "unprognostic (1.69e-1)" "unprognostic (3.84e-1)" "unprognostic (4.93e-1)" "unprognostic (8.79e-3)" "unprognostic (1.03e-1)" "unprognostic (8.01e-3)" "potential prognostic favorable (7.66e-5)" "unprognostic (8.07e-3)" "unprognostic (2.02e-1)" "unprognostic (4.63e-2)" "unprognostic (6.12e-2)" "unprognostic (1.61e-1)" "potential prognostic unfavorable (4.46e-4)" "unprognostic (8.86e-2)" "unprognostic (1.31e-2)" "unprognostic (2.08e-1)" "unprognostic (1.09e-2)" "unprognostic (1.35e-1)" "unprognostic (3.73e-3)" "unprognostic (6.48e-2)" "unprognostic (4.89e-2)" "unprognostic (3.67e-3)" "unprognostic (5.10e-2)" "unprognostic (3.19e-1)" "unprognostic (2.09e-1)" "unprognostic (1.77e-2)" "unprognostic (1.77e-1)" ATXN1 "ATX1, D6S504E, SCA1" ENSG00000124788 "Ataxin 1" P54253 6 16299112-16761491 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor, RNA-binding" "Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 1684.8;Neutrophils: 2569.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008335, HPA070756" Approved Supported Nucleoplasm,Nucleoli,Cytosol Yes No "Cluster 28: Neutrophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 72: Neuronal - Signal transduction" "Cluster 9: T-cells - Adaptive immunity: Regulation" 401 Nucleoplasm "Nucleoli, Cytosol" "HPA008335: , HPA070756: " "unprognostic (3.81e-2)" "unprognostic (1.71e-1)" "unprognostic (1.29e-1)" "unprognostic (2.55e-2)" "unprognostic (2.12e-1)" "unprognostic (1.05e-1)" "unprognostic (2.76e-1)" "unprognostic (4.57e-2)" "unprognostic (5.49e-2)" "unprognostic (4.63e-2)" "validated prognostic favorable (1.78e-5)" "validated prognostic favorable (1.01e-4)" "unprognostic (1.84e-1)" "unprognostic (6.41e-2)" "unprognostic (1.78e-1)" "unprognostic (7.92e-2)" "unprognostic (2.12e-2)" "unprognostic (5.53e-2)" "unprognostic (1.21e-1)" "unprognostic (3.45e-1)" "unprognostic (2.34e-1)" "unprognostic (9.54e-2)" "unprognostic (5.25e-2)" "unprognostic (1.15e-1)" "unprognostic (6.37e-2)" "unprognostic (3.34e-2)" "unprognostic (1.47e-1)" "unprognostic (9.65e-2)" "unprognostic (2.70e-1)" "unprognostic (1.25e-2)" "unprognostic (1.78e-1)" ATXN10 "ATX10, E46L, FLJ37990, SCA10" ENSG00000130638 "Ataxin 10" Q9UBB4 22 45671798-45845307 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" "Ciliopathy, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049531 Approved Approved "Plasma membrane,Primary cilium,Cytosol" NA NA 23000 "Cluster 33: Non-specific - ATP binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 66: Non-specific - Mitochondria" "Cluster 7: Non-specific - Transcription" 63 "Plasma membrane" "Primary cilium, Cytosol" "HPA049531: " "unprognostic (5.78e-2)" "unprognostic (5.73e-3)" "unprognostic (3.20e-2)" "unprognostic (1.64e-1)" "unprognostic (6.37e-3)" "unprognostic (6.43e-2)" "unprognostic (3.01e-2)" "unprognostic (2.31e-1)" "unprognostic (7.03e-2)" "unprognostic (5.32e-3)" "potential prognostic favorable (1.88e-7)" "unprognostic (8.63e-2)" "unprognostic (3.65e-1)" "potential prognostic unfavorable (4.99e-4)" "unprognostic (1.29e-2)" "unprognostic (9.51e-3)" "unprognostic (1.36e-1)" "unprognostic (4.10e-2)" "unprognostic (5.48e-3)" "unprognostic (1.43e-2)" "unprognostic (3.88e-1)" "unprognostic (2.40e-1)" "unprognostic (3.76e-3)" "unprognostic (5.18e-2)" "unprognostic (1.88e-1)" "unprognostic (6.61e-2)" "unprognostic (1.16e-2)" "unprognostic (2.22e-1)" "unprognostic (1.64e-1)" "unprognostic (2.57e-2)" "unprognostic (4.12e-2)" ATXN1L BOAT1 ENSG00000224470 "Ataxin 1 like" P0C7T5 16 71808439-71885268 "Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 61.5;Cardiomyocytes: 95.4;Cone photoreceptor cells: 93.2;Epicardial cells: 109.2;Sertoli cells: 97.1;Somatotrophs: 69.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062596, HPA062789" Supported Nucleoplasm,Nucleoli NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 19: Astrocytes - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 32 Nucleoplasm Nucleoli "HPA062596: , HPA062789: " "unprognostic (1.77e-1)" "unprognostic (2.16e-1)" "unprognostic (1.59e-1)" "unprognostic (4.19e-2)" "unprognostic (1.66e-1)" "unprognostic (1.03e-1)" "unprognostic (3.41e-2)" "unprognostic (1.38e-1)" "unprognostic (7.18e-2)" "unprognostic (4.65e-1)" "validated prognostic favorable (7.03e-9)" "validated prognostic favorable (1.89e-4)" "unprognostic (1.69e-2)" "unprognostic (6.52e-2)" "unprognostic (8.47e-2)" "unprognostic (1.35e-2)" "unprognostic (7.53e-2)" "unprognostic (1.94e-1)" "unprognostic (1.98e-2)" "unprognostic (4.55e-2)" "unprognostic (1.08e-2)" "unprognostic (1.64e-2)" "unprognostic (6.11e-3)" "unprognostic (1.84e-1)" "unprognostic (1.46e-2)" "unprognostic (3.42e-2)" "unprognostic (1.22e-1)" "unprognostic (2.10e-1)" "unprognostic (2.82e-1)" "unprognostic (2.32e-2)" "unprognostic (2.47e-1)" ATXN2 "ATX2, SCA2, TNRC13" ENSG00000204842 "Ataxin 2" Q99700 12 111443485-111599676 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Amyotrophic lateral sclerosis, Neurodegeneration, Parkinsonism, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018295, HPA020339, HPA021146" Enhanced Approved Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 74: Non-specific - Signal transduction" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 38: Non-specific - Transcription" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 88 Cytosol "HPA018295: , HPA020339: , HPA021146: " "unprognostic (3.37e-2)" "unprognostic (2.38e-2)" "unprognostic (4.18e-1)" "unprognostic (7.53e-2)" "unprognostic (1.30e-1)" "unprognostic (6.60e-2)" "unprognostic (2.89e-1)" "unprognostic (1.54e-1)" "unprognostic (6.43e-2)" "unprognostic (3.77e-2)" "unprognostic (3.11e-2)" "unprognostic (5.26e-1)" "unprognostic (1.17e-1)" "potential prognostic unfavorable (7.30e-7)" "unprognostic (1.61e-2)" "unprognostic (2.84e-3)" "unprognostic (4.28e-1)" "unprognostic (1.48e-1)" "unprognostic (5.18e-2)" "unprognostic (6.60e-2)" "unprognostic (1.03e-1)" "unprognostic (3.08e-1)" "potential prognostic unfavorable (6.42e-4)" "unprognostic (1.59e-1)" "unprognostic (2.09e-1)" "unprognostic (1.86e-1)" "unprognostic (7.41e-3)" "unprognostic (6.19e-2)" "unprognostic (6.69e-2)" "unprognostic (3.02e-1)" "unprognostic (2.71e-1)" ATXN2L "A2D, A2lp" ENSG00000168488 "Ataxin 2 like" Q8WWM7 16 28822999-28837237 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041506, HPA043391, HPA071955" Approved Enhanced Cytosol NA NA 72000 "Cluster 30: Non-specific - DNA binding" "Cluster 67: Testis - Mixed function" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 13: Non-specific - Mixed function" "Cluster 20: Non-specific - Transcription regulation" 37 Cytosol "HPA041506: , HPA043391: , HPA071955: " "unprognostic (1.23e-1)" "unprognostic (9.65e-3)" "unprognostic (2.29e-1)" "unprognostic (3.55e-2)" "unprognostic (1.07e-2)" "unprognostic (5.57e-2)" "unprognostic (2.95e-1)" "unprognostic (2.11e-1)" "unprognostic (2.00e-1)" "unprognostic (1.61e-1)" "validated prognostic unfavorable (1.51e-11)" "validated prognostic unfavorable (1.45e-4)" "unprognostic (2.88e-2)" "potential prognostic unfavorable (1.12e-4)" "unprognostic (1.14e-1)" "unprognostic (3.27e-3)" "unprognostic (4.16e-2)" "unprognostic (6.14e-2)" "unprognostic (8.97e-2)" "unprognostic (7.32e-2)" "unprognostic (1.50e-3)" "unprognostic (1.89e-1)" "potential prognostic unfavorable (3.80e-4)" "unprognostic (7.67e-2)" "unprognostic (2.07e-1)" "unprognostic (8.23e-3)" "unprognostic (1.31e-1)" "unprognostic (9.60e-2)" "unprognostic (5.01e-1)" "unprognostic (3.39e-1)" "unprognostic (1.15e-1)" ATXN3 "ATX3, JOS, MJD, SCA3" ENSG00000066427 "Ataxin 3" P54252 14 92044496-92106621 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB021976, HPA024123, HPA069338" Uncertain Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 58: Skin - Keratinization" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 142 "Nucleoplasm, Nucleoli" "Plasma membrane" "CAB021976: , HPA024123: , HPA069338: " "unprognostic (1.26e-1)" "unprognostic (3.28e-1)" "unprognostic (1.53e-1)" "unprognostic (1.39e-2)" "unprognostic (1.08e-1)" "unprognostic (1.72e-2)" "unprognostic (2.86e-1)" "unprognostic (3.15e-2)" "unprognostic (1.34e-2)" "unprognostic (4.86e-2)" "potential prognostic favorable (1.91e-4)" "unprognostic (1.15e-2)" "unprognostic (1.04e-1)" "unprognostic (1.04e-1)" "unprognostic (3.48e-3)" "unprognostic (1.21e-2)" "unprognostic (3.47e-2)" "unprognostic (2.91e-1)" "unprognostic (2.14e-1)" "unprognostic (7.43e-2)" "potential prognostic unfavorable (1.63e-4)" "unprognostic (1.07e-2)" "unprognostic (2.04e-2)" "unprognostic (5.45e-2)" "unprognostic (1.73e-1)" "unprognostic (1.07e-2)" "unprognostic (1.34e-1)" "unprognostic (2.91e-3)" "unprognostic (1.74e-1)" "unprognostic (8.46e-2)" "unprognostic (1.52e-2)" ATXN3L MJDL ENSG00000123594 "Ataxin 3 like" Q9H3M9 X 13318647-13320053 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 40 "testis: 4.4" "Cell type enriched" "Detected in some" 4 "Late spermatids: 363.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "thyroid cancer: 1.4" "Testis - Late spermatids" "HPA024123, HPA027539" Uncertain NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 3 "HPA024123: , HPA027539: " ATXN7 "ADCAII, OPCA3, SCA7, SGF73" ENSG00000163635 "Ataxin 7" O15265 3 63863155-64003462 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epicardial cells: 382.1;Neutrophils: 426.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 15.9" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034989 Supported Nucleoplasm,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 8: Pancreas - Proteolysis" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 103: Non-specific - Basic cellular processes" 49 "Nucleoplasm, Cytosol" "HPA034989: " "unprognostic (2.72e-2)" "unprognostic (1.76e-1)" "unprognostic (7.90e-2)" "unprognostic (1.38e-1)" "unprognostic (2.78e-1)" "unprognostic (1.80e-2)" "unprognostic (1.59e-1)" "unprognostic (1.40e-1)" "potential prognostic favorable (3.48e-4)" "unprognostic (3.77e-2)" "unprognostic (1.83e-3)" "unprognostic (7.45e-3)" "unprognostic (2.99e-1)" "unprognostic (4.38e-2)" "unprognostic (6.62e-3)" "unprognostic (2.09e-3)" "unprognostic (6.63e-3)" "unprognostic (1.41e-2)" "unprognostic (1.76e-1)" "unprognostic (8.10e-2)" "unprognostic (1.02e-1)" "unprognostic (2.46e-2)" "unprognostic (8.78e-3)" "unprognostic (1.39e-2)" "unprognostic (1.47e-3)" "unprognostic (2.21e-3)" "unprognostic (1.13e-1)" "unprognostic (1.46e-1)" "unprognostic (2.92e-1)" "unprognostic (2.66e-2)" "unprognostic (2.23e-2)" ATXN7L1 "ATXN7L4, KIAA1218, MGC33190" ENSG00000146776 "Ataxin 7 like 1" Q9ULK2 7 105604772-105876599 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubule cells: 372.2;Sertoli cells: 358.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021448 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 39: Testis - Nuclear processes" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 39: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 8 "Nucleoplasm, Cytosol" "HPA021448: " "unprognostic (4.66e-2)" "unprognostic (1.66e-1)" "unprognostic (3.51e-1)" "unprognostic (2.36e-1)" "unprognostic (3.72e-2)" "unprognostic (3.01e-2)" "unprognostic (3.61e-1)" "unprognostic (1.75e-1)" "unprognostic (1.02e-1)" "potential prognostic unfavorable (1.16e-4)" "validated prognostic favorable (1.05e-4)" "validated prognostic favorable (2.15e-4)" "unprognostic (9.74e-3)" "unprognostic (2.70e-2)" "unprognostic (2.16e-1)" "unprognostic (2.68e-2)" "unprognostic (2.56e-2)" "unprognostic (1.49e-2)" "unprognostic (2.53e-1)" "unprognostic (1.64e-2)" "unprognostic (3.38e-1)" "unprognostic (7.04e-3)" "unprognostic (1.23e-2)" "unprognostic (1.88e-1)" "unprognostic (4.83e-2)" "unprognostic (2.64e-1)" "unprognostic (1.26e-3)" "unprognostic (3.38e-1)" "unprognostic (9.70e-2)" "unprognostic (5.46e-2)" "unprognostic (1.50e-1)" ATXN7L2 "FLJ00381, MGC46534" ENSG00000162650 "Ataxin 7 like 2" Q5T6C5 1 109483479-109492804 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 10.6;Astrocytes: 8.5;Myonuclei: 21.5;Sertoli cells: 18.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Minor Salivary Gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029827, HPA054952" Uncertain Approved "Nucleoli rim,Vesicles,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 51: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 16 "Nucleoli rim" "Vesicles, Cytosol" "HPA029827: , HPA054952: " "unprognostic (2.27e-2)" "unprognostic (3.72e-1)" "unprognostic (3.19e-1)" "unprognostic (1.48e-1)" "unprognostic (2.04e-2)" "unprognostic (1.75e-1)" "unprognostic (6.02e-2)" "unprognostic (1.31e-3)" "unprognostic (2.25e-2)" "unprognostic (1.10e-1)" "unprognostic (9.39e-3)" "unprognostic (1.51e-1)" "unprognostic (2.12e-1)" "unprognostic (2.38e-1)" "unprognostic (1.15e-1)" "unprognostic (2.75e-2)" "unprognostic (2.24e-2)" "potential prognostic favorable (5.47e-4)" "unprognostic (6.13e-2)" "unprognostic (2.93e-1)" "unprognostic (2.05e-2)" "unprognostic (3.31e-1)" "unprognostic (9.27e-2)" "unprognostic (2.39e-3)" ATXN7L3 DKFZp761G2113 ENSG00000087152 "Ataxin 7 like 3" Q14CW9 17 44191805-44200113 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 58.5;Neutrophils: 59.3;Platelets: 54.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064316 Supported Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 17: Non-specific - RNA processing" 30 "Nuclear speckles" "Plasma membrane" "HPA064316: " "unprognostic (1.07e-1)" "unprognostic (3.89e-1)" "unprognostic (1.67e-1)" "unprognostic (3.49e-3)" "unprognostic (2.71e-1)" "unprognostic (1.04e-2)" "unprognostic (2.63e-2)" "unprognostic (7.40e-2)" "unprognostic (1.24e-1)" "unprognostic (2.36e-1)" "unprognostic (1.79e-1)" "unprognostic (3.23e-1)" "unprognostic (2.12e-1)" "potential prognostic unfavorable (7.48e-5)" "unprognostic (2.23e-2)" "unprognostic (1.33e-2)" "unprognostic (6.65e-3)" "unprognostic (2.11e-2)" "unprognostic (8.94e-3)" "unprognostic (2.89e-2)" "unprognostic (3.01e-1)" "unprognostic (3.52e-1)" "unprognostic (3.79e-2)" "unprognostic (2.55e-1)" "unprognostic (5.60e-2)" "unprognostic (1.03e-1)" "unprognostic (5.37e-2)" "unprognostic (6.16e-2)" "unprognostic (1.64e-1)" "unprognostic (3.21e-2)" "unprognostic (4.16e-2)" ATXN7L3B lnc-SCA7 ENSG00000253719 "Ataxin 7 like 3B" Q96GX2 12 74537835-74545430 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056612 Approved Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 14: Neurons - Synaptic function" "Cluster 38: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 4 Nucleoplasm "HPA056612: " "unprognostic (1.86e-1)" "unprognostic (6.87e-3)" "unprognostic (6.63e-2)" "unprognostic (1.94e-1)" "unprognostic (2.43e-2)" "unprognostic (3.41e-1)" "unprognostic (3.06e-1)" "unprognostic (1.92e-1)" "unprognostic (4.22e-2)" "unprognostic (1.28e-1)" "validated prognostic favorable (1.74e-9)" "validated prognostic favorable (3.65e-4)" "unprognostic (3.10e-1)" "unprognostic (2.58e-3)" "unprognostic (1.74e-3)" "unprognostic (7.99e-2)" "unprognostic (2.96e-2)" "unprognostic (5.15e-2)" "unprognostic (5.52e-2)" "unprognostic (6.09e-2)" "unprognostic (5.57e-2)" "unprognostic (9.34e-2)" "unprognostic (1.11e-2)" "unprognostic (1.45e-1)" "unprognostic (3.12e-1)" "unprognostic (1.16e-1)" "unprognostic (2.50e-2)" "unprognostic (1.96e-1)" "unprognostic (1.58e-1)" "unprognostic (6.07e-2)" "unprognostic (1.42e-1)" AUH ENSG00000148090 "AU RNA binding methylglutaconyl-CoA hydratase" Q13825 9 91213815-91361918 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Branched-chain amino acid catabolism" "Lyase, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Stomach - Parietal cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004171, HPA075060" Enhanced Approved Vesicles,Centrosome,Cytosol NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 76: Non-specific - Metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 9 Cytosol "Vesicles, Centrosome" "HPA004171: , HPA075060: " "unprognostic (5.29e-3)" "unprognostic (4.69e-3)" "unprognostic (8.85e-2)" "unprognostic (2.61e-1)" "unprognostic (3.42e-1)" "unprognostic (4.90e-1)" "unprognostic (6.99e-2)" "unprognostic (9.14e-3)" "unprognostic (7.71e-3)" "unprognostic (1.64e-1)" "validated prognostic favorable (7.22e-15)" "validated prognostic favorable (5.63e-5)" "potential prognostic favorable (1.12e-4)" "unprognostic (1.15e-1)" "unprognostic (1.37e-2)" "unprognostic (6.52e-2)" "unprognostic (6.72e-3)" "unprognostic (1.34e-3)" "unprognostic (1.28e-1)" "potential prognostic unfavorable (5.04e-4)" "unprognostic (7.71e-2)" "unprognostic (2.14e-1)" "unprognostic (2.69e-2)" "unprognostic (1.51e-1)" "unprognostic (1.01e-1)" "unprognostic (7.56e-2)" "unprognostic (1.84e-1)" "unprognostic (1.61e-2)" "unprognostic (3.91e-1)" "unprognostic (2.03e-1)" "unprognostic (2.90e-2)" AUNIP "AIBp, C1orf135, MGC2603" ENSG00000127423 "Aurora kinase A and ninein interacting protein" Q9H7T9 1 25831913-25859458 "Predicted intracellular proteins" "DNA damage, DNA repair" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 5.9;testis: 14.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 75.4;Differentiating spermatogonia: 38.8;Early primary spermatocytes: 81.1;Early spermatids: 66.5;Epicardial cells: 47.8;Late primary spermatocytes: 44.0;Late spermatids: 186.0;Oocytes: 78.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Inner root sheath cells, Skin - Outer root sheath cells, Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA028730 Uncertain Supported Centrosome NA NA "Cluster 41: Basophils - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 37: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 12 Centrosome "HPA028730: " "unprognostic (6.91e-2)" "unprognostic (6.76e-2)" "unprognostic (6.58e-2)" "unprognostic (3.90e-2)" "unprognostic (2.47e-1)" "unprognostic (1.08e-1)" "unprognostic (9.39e-3)" "unprognostic (1.15e-1)" "unprognostic (1.36e-3)" "unprognostic (1.64e-3)" "unprognostic (3.26e-2)" "potential prognostic favorable (7.58e-4)" "unprognostic (4.95e-3)" "unprognostic (3.11e-2)" "potential prognostic unfavorable (6.95e-4)" "unprognostic (2.84e-2)" "potential prognostic unfavorable (5.64e-4)" "unprognostic (1.13e-1)" "unprognostic (2.40e-2)" "unprognostic (6.73e-2)" "unprognostic (5.28e-2)" "unprognostic (1.67e-1)" "unprognostic (1.51e-2)" AUP1 ENSG00000115307 "AUP1 lipid droplet regulating VLDL assembly factor" Q9Y679 2 74526645-74529760 "Predicted membrane proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 263.8;Extravillous trophoblasts: 278.9;Syncytiotrophoblasts: 264.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA007674 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 27: Breast cancer - Unknown function" "Cluster 8: Non-specific - Secretory pathway" 36 "Nucleoplasm, Vesicles" "HPA007674: " "unprognostic (1.38e-2)" "unprognostic (3.29e-2)" "unprognostic (3.71e-1)" "unprognostic (1.76e-3)" "unprognostic (7.62e-2)" "unprognostic (9.76e-2)" "unprognostic (4.62e-1)" "unprognostic (2.80e-2)" "potential prognostic unfavorable (6.37e-6)" "unprognostic (6.40e-2)" "unprognostic (1.22e-2)" "unprognostic (8.07e-3)" "unprognostic (6.25e-2)" "validated prognostic unfavorable (1.91e-4)" "validated prognostic unfavorable (7.55e-5)" "potential prognostic unfavorable (2.37e-4)" "unprognostic (7.81e-2)" "unprognostic (7.52e-3)" "unprognostic (3.84e-2)" "unprognostic (4.22e-2)" "unprognostic (8.15e-2)" "unprognostic (3.08e-2)" "potential prognostic unfavorable (8.88e-4)" "unprognostic (9.14e-2)" "unprognostic (1.12e-1)" "unprognostic (2.03e-1)" "unprognostic (6.79e-2)" "unprognostic (9.34e-2)" "unprognostic (2.63e-1)" "unprognostic (2.13e-1)" "unprognostic (1.15e-1)" AURKA "AIK, ARK1, AurA, BTAK, PPP1R47, STK15, STK6, STK7" ENSG00000087586 "Aurora kinase A" O14965 20 56369389-56392337 "Cancer-related genes, Enzymes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Cilium biogenesis/degradation, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 20.6;testis: 28.8" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 49.5;Erythrocyte progenitors: 61.8;Extravillous trophoblasts: 77.4;Late primary spermatocytes: 269.3;Migrating cytotrophoblasts: 57.4;Monocyte progenitors: 90.0;Oocytes: 354.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001454, HPA002636" Enhanced Supported "Nucleoplasm,Mitotic spindle,Centrosome,Basal body,Cytosol" Yes Yes "Cluster 25: Non-specific - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 25: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 27: Non-specific - Cell proliferation" 147 "Mitotic spindle, Centrosome, Basal body" "Nucleoplasm, Cytosol" "CAB001454: , HPA002636: " "unprognostic (7.08e-3)" "unprognostic (2.22e-2)" "unprognostic (7.02e-2)" "unprognostic (1.67e-1)" "unprognostic (3.90e-2)" "unprognostic (1.16e-2)" "unprognostic (1.99e-1)" "unprognostic (3.96e-2)" "unprognostic (9.98e-2)" "potential prognostic unfavorable (9.06e-7)" "validated prognostic unfavorable (2.02e-7)" "validated prognostic unfavorable (6.11e-6)" "potential prognostic unfavorable (1.01e-5)" "validated prognostic unfavorable (4.15e-5)" "validated prognostic unfavorable (1.47e-9)" "potential prognostic unfavorable (6.92e-5)" "unprognostic (8.87e-3)" "unprognostic (2.32e-2)" "unprognostic (1.22e-1)" "unprognostic (9.22e-2)" "unprognostic (2.68e-1)" "potential prognostic unfavorable (2.32e-4)" "unprognostic (6.72e-3)" "unprognostic (4.75e-2)" "unprognostic (3.41e-2)" "unprognostic (6.65e-3)" "unprognostic (2.60e-2)" "unprognostic (1.23e-1)" "unprognostic (1.52e-1)" "unprognostic (5.78e-3)" "unprognostic (7.53e-2)" AURKAIP1 "AIP, AKIP, FLJ20608" ENSG00000175756 "Aurora kinase A interacting protein 1" Q9NWT8 1 1373730-1375207 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 1255.5;Late primary spermatocytes: 1444.9;Late spermatids: 5716.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031821 Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 37: Non-specific - mRNA processing" "Cluster 97: Non-specific - Cellular respiration" 84 "Nucleoplasm, Mitochondria" "HPA031821: " "unprognostic (2.82e-1)" "unprognostic (2.54e-1)" "unprognostic (8.79e-2)" "unprognostic (7.82e-2)" "unprognostic (3.80e-2)" "unprognostic (8.05e-3)" "unprognostic (1.19e-1)" "unprognostic (4.14e-1)" "unprognostic (5.03e-2)" "unprognostic (1.26e-1)" "unprognostic (5.19e-2)" "unprognostic (2.50e-1)" "potential prognostic favorable (2.52e-4)" "unprognostic (1.49e-1)" "potential prognostic unfavorable (1.94e-4)" "unprognostic (9.95e-2)" "unprognostic (6.52e-2)" "unprognostic (1.63e-1)" "unprognostic (3.75e-1)" "unprognostic (9.36e-2)" "unprognostic (1.07e-1)" "unprognostic (3.80e-2)" "unprognostic (2.25e-1)" "unprognostic (3.59e-1)" "unprognostic (1.47e-1)" "unprognostic (8.37e-2)" "unprognostic (2.41e-1)" "unprognostic (7.19e-2)" "unprognostic (1.82e-1)" "unprognostic (6.18e-2)" "unprognostic (7.41e-2)" AURKB "Aik2, AIM-1, ARK2, AurB, IPL1, PPP1R48, STK12, STK5" ENSG00000178999 "Aurora kinase B" Q96GD4 17 8204733-8210600 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 41.6;lymphoid tissue: 55.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 46.7;Enteric transient amplifying cells: 60.0;Erythrocyte progenitors: 49.5;Esophageal basal cells: 59.6;Extravillous trophoblasts: 102.8;Gastric progenitor cells: 28.2;Hofbauer cells: 48.5;Megakaryocyte progenitors: 41.1;Migrating cytotrophoblasts: 77.2;Monocyte progenitors: 80.5;Neutrophil progenitors: 29.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "T-reg: 7.9" "Group enriched" "Detected in many" 6 "B-cells: 2.5;T-cells: 7.9" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Thyroid gland - Mitotic cells (Thyroid)" "Group enriched" "Detected in some" 5 "basal ganglia: 1.3;white matter: 4.0" "Low region specificity" "Detected in all" "CAB005862, HPA037708" Enhanced Supported Nucleoplasm,Kinetochore,Midbody Yes Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 25: Non-specific - Transcription" "Cluster 42: Non-specific - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 151 Nucleoplasm "Kinetochore, Midbody" "CAB005862: , HPA037708: " "unprognostic (1.96e-2)" "unprognostic (5.09e-2)" "unprognostic (1.76e-1)" "unprognostic (1.23e-2)" "unprognostic (1.25e-1)" "unprognostic (5.70e-2)" "unprognostic (2.67e-1)" "unprognostic (8.70e-3)" "unprognostic (2.53e-1)" "potential prognostic unfavorable (3.78e-6)" "validated prognostic unfavorable (3.24e-10)" "validated prognostic unfavorable (5.06e-4)" "potential prognostic unfavorable (2.76e-9)" "validated prognostic unfavorable (3.33e-5)" "validated prognostic unfavorable (1.20e-8)" "potential prognostic unfavorable (1.08e-4)" "unprognostic (2.38e-3)" "unprognostic (2.47e-2)" "unprognostic (1.03e-1)" "unprognostic (1.45e-1)" "unprognostic (2.75e-2)" "unprognostic (2.95e-3)" "unprognostic (8.10e-3)" "unprognostic (1.37e-3)" "unprognostic (1.15e-1)" "unprognostic (1.10e-1)" "unprognostic (1.30e-2)" "unprognostic (7.08e-2)" "unprognostic (1.80e-1)" "unprognostic (3.32e-2)" "unprognostic (1.22e-1)" AURKC "ARK3, AurC, STK13" ENSG00000105146 "Aurora kinase C" Q9UQB9 19 57231009-57235548 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Meiosis, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "testis: 44.6" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 19.7;Early primary spermatocytes: 34.4;Early spermatids: 121.1;Late primary spermatocytes: 290.1;Late spermatids: 26.6;Oocytes: 64.5;Undifferentiated spermatogonia: 21.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA034859 Uncertain NA NA "Cluster 47: Testis - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 8 "HPA034859: " "unprognostic (8.13e-2)" "unprognostic (7.89e-2)" "unprognostic (8.35e-3)" "unprognostic (7.20e-2)" "unprognostic (6.38e-2)" "unprognostic (1.30e-1)" "unprognostic (1.42e-1)" "unprognostic (1.20e-3)" "potential prognostic unfavorable (3.55e-6)" "unprognostic (3.06e-2)" "unprognostic (4.17e-2)" "unprognostic (8.85e-2)" "unprognostic (7.55e-2)" "unprognostic (2.19e-2)" "unprognostic (2.14e-1)" "unprognostic (1.52e-1)" "unprognostic (9.81e-3)" "unprognostic (3.02e-1)" "unprognostic (4.86e-1)" "potential prognostic favorable (5.37e-4)" "unprognostic (4.27e-2)" "unprognostic (5.00e-2)" "unprognostic (9.45e-2)" "unprognostic (2.66e-1)" "unprognostic (1.54e-1)" "unprognostic (1.02e-2)" AUTS2 "FBRSL2, KIAA0442" ENSG00000158321 "Activator of transcription and developmental regulator AUTS2" Q8WXX7 7 69598296-70793506 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Autism, Autism spectrum disorder, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Corticotrophs: 2209.8;Lactotrophs: 2233.2;Retinal amacrine cells: 2094.1;Retinal horizontal cells: 3439.8;Somatotrophs: 1998.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 8.0;naive B-cell: 9.3" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000390 Approved Supported "Nucleoplasm,Plasma membrane,Cell Junctions,Cytosol" Yes No "Cluster 14: Non-specific - Unknown function" "Cluster 2: Non-specific - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" 21 Nucleoplasm "Plasma membrane, Cell Junctions, Cytosol" "HPA000390: " "unprognostic (1.48e-1)" "unprognostic (2.57e-1)" "unprognostic (3.87e-1)" "unprognostic (1.68e-1)" "unprognostic (1.51e-1)" "unprognostic (5.48e-2)" "unprognostic (7.86e-2)" "unprognostic (8.92e-2)" "unprognostic (3.53e-2)" "unprognostic (3.52e-2)" "validated prognostic favorable (9.09e-9)" "validated prognostic favorable (8.25e-5)" "unprognostic (6.50e-3)" "unprognostic (5.43e-2)" "potential prognostic favorable (5.50e-4)" "unprognostic (1.09e-1)" "unprognostic (5.82e-2)" "unprognostic (1.01e-1)" "unprognostic (8.43e-2)" "unprognostic (7.63e-2)" "unprognostic (8.71e-2)" "unprognostic (1.68e-1)" "unprognostic (1.03e-2)" "unprognostic (3.23e-1)" "unprognostic (1.33e-2)" "unprognostic (4.51e-3)" "unprognostic (2.55e-2)" "unprognostic (2.55e-2)" "unprognostic (1.74e-1)" "unprognostic (2.16e-1)" "unprognostic (1.69e-1)" AVEN PDCD12 ENSG00000169857 "Apoptosis and caspase activation inhibitor" Q9NQS1 15 33858782-34075155 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Oocytes: 428.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 2.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020863 Approved Approved "Plasma membrane,Actin filaments,Centrosome" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 44: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 7: Non-specific - Transcription" 7 "Plasma membrane, Actin filaments" Centrosome "HPA020863: " "unprognostic (1.17e-1)" "unprognostic (1.36e-2)" "unprognostic (1.20e-2)" "unprognostic (9.11e-2)" "unprognostic (1.74e-1)" "unprognostic (7.74e-2)" "unprognostic (2.97e-1)" "unprognostic (5.62e-3)" "unprognostic (1.22e-1)" "potential prognostic unfavorable (1.71e-6)" "unprognostic (3.25e-3)" "unprognostic (7.73e-3)" "unprognostic (2.90e-3)" "unprognostic (2.91e-1)" "potential prognostic unfavorable (3.45e-5)" "potential prognostic unfavorable (1.26e-7)" "unprognostic (1.81e-2)" "unprognostic (2.22e-1)" "unprognostic (1.48e-2)" "unprognostic (2.67e-1)" "unprognostic (1.89e-2)" "unprognostic (3.48e-3)" "unprognostic (1.37e-1)" "unprognostic (2.42e-1)" "unprognostic (7.31e-2)" "unprognostic (1.23e-2)" "unprognostic (1.21e-1)" "unprognostic (1.96e-2)" "unprognostic (4.41e-1)" "unprognostic (2.89e-1)" "unprognostic (3.12e-1)" AVIL "ADVIL, DOC6, FLJ12386, p92" ENSG00000135407 Advillin O75366 12 57797376-57818734 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 5 "Tuft cells: 611.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 6.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "neutrophil: 2.0" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.0" "Cancer enhanced" "Detected in some" "lung cancer: 6.6" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA058864 Approved NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 15: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 95: Tuft cells - Chemosensory signaling" 1 "HPA058864: " "unprognostic (9.53e-2)" "unprognostic (8.72e-3)" "unprognostic (4.01e-3)" "unprognostic (4.57e-3)" "unprognostic (1.03e-1)" "unprognostic (6.03e-2)" "unprognostic (3.65e-2)" "unprognostic (3.07e-3)" "unprognostic (3.19e-2)" "unprognostic (2.51e-1)" "unprognostic (3.29e-1)" "unprognostic (3.38e-1)" "unprognostic (1.19e-1)" "unprognostic (1.58e-1)" "unprognostic (2.78e-1)" "unprognostic (1.20e-1)" "unprognostic (2.22e-2)" "unprognostic (1.18e-1)" "unprognostic (1.77e-1)" "unprognostic (5.82e-2)" "unprognostic (3.56e-1)" "unprognostic (1.61e-1)" "unprognostic (1.09e-2)" AVL9 KIAA0241 ENSG00000105778 "AVL9 cell migration associated" Q8NBF6 7 32495426-32588726 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 383.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050957 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 42: Retina - Visual perception" "Cluster 14: Neurons - Synaptic function" "Cluster 67: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" "Endoplasmic reticulum" "HPA050957: " "unprognostic (1.71e-1)" "unprognostic (2.61e-2)" "unprognostic (5.18e-2)" "unprognostic (1.02e-3)" "unprognostic (3.09e-1)" "unprognostic (5.10e-2)" "unprognostic (9.18e-2)" "unprognostic (1.00e-1)" "unprognostic (2.11e-1)" "unprognostic (4.69e-3)" "unprognostic (8.90e-3)" "unprognostic (2.10e-1)" "unprognostic (1.31e-1)" "unprognostic (1.26e-2)" "unprognostic (1.55e-2)" "unprognostic (8.51e-3)" "unprognostic (7.36e-3)" "unprognostic (6.71e-2)" "unprognostic (1.55e-1)" "unprognostic (1.53e-1)" "unprognostic (9.84e-2)" "unprognostic (1.52e-2)" "unprognostic (2.13e-3)" "unprognostic (2.47e-1)" "unprognostic (4.36e-3)" "unprognostic (4.19e-1)" "unprognostic (1.27e-1)" "unprognostic (4.67e-2)" "unprognostic (3.41e-1)" "unprognostic (1.79e-2)" "unprognostic (3.83e-2)" AVP "ADH, ARVP" ENSG00000101200 "Arginine vasopressin" P01185 20 3082556-3084724 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Host-virus interaction" "Hormone, Vasoactive, Vasoconstrictor" "Diabetes insipidus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 747 "brain: 4348.0" "Group enriched" "Detected in some" 5 "Hematopoietic stem cells: 613.3;Other brain neurons: 757.0" "Cell type enriched" "Detected in many" 4 "splatter: 32.1" "Not detected" "Not detected" "Region enriched" "Detected in many" 76 "hypothalamus: 15977.0" "Immune cell enriched" "Detected in single" 6 "eosinophil: 2.8" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.8" "Cancer enriched" "Detected in single" 108 "Leukemia: 13.5" "Kidney - Proximal tubular cells, Testis - Late spermatids" "Region enriched" "Detected in many" 10 "hypothalamus: 232.8" "Group enriched" "Detected in many" 489 "basal ganglia: 2270.2;hypothalamus: 2082.9" "CAB025318, HPA071892" Enhanced Supported "Secreted to blood" Hormone NA NA 19300 140000 "Cluster 36: Brain & Liver - Signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 47: Leukemia - Hemostasis" "Cluster 109: Neurons - Neuronal signaling" 2 "CAB025318: , HPA071892: " AVPI1 "PP5395, VIP32, VIT32" ENSG00000119986 "Arginine vasopressin induced 1" Q5T686 10 97677424-97687241 "Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 104.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 194.9;Esophageal apical cells: 230.4;Late spermatids: 476.7;Syncytiotrophoblasts: 264.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 129.7" "Minor Salivary Gland - Minor salivary gland basal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037649 Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 30: White matter - Myelination" "Cluster 7: Liver cancer - Metabolism" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 33 "Nucleoplasm, Plasma membrane" "HPA037649: " "unprognostic (1.69e-2)" "unprognostic (1.19e-1)" "unprognostic (3.63e-1)" "unprognostic (1.86e-2)" "unprognostic (1.94e-1)" "unprognostic (2.83e-1)" "unprognostic (1.19e-2)" "unprognostic (3.71e-1)" "unprognostic (1.11e-1)" "unprognostic (4.00e-1)" "unprognostic (2.84e-3)" "unprognostic (2.52e-1)" "unprognostic (2.05e-1)" "unprognostic (8.84e-3)" "unprognostic (1.09e-2)" "potential prognostic unfavorable (5.75e-4)" "unprognostic (2.61e-2)" "unprognostic (1.00e-1)" "unprognostic (1.15e-1)" "unprognostic (2.46e-2)" "unprognostic (5.96e-2)" "unprognostic (1.19e-3)" "unprognostic (2.28e-1)" "unprognostic (8.33e-3)" "unprognostic (2.51e-1)" "unprognostic (1.11e-2)" "unprognostic (1.99e-3)" "unprognostic (2.23e-1)" "unprognostic (8.58e-2)" "unprognostic (1.81e-2)" "unprognostic (1.65e-1)" AVPR1A AVPR1 ENSG00000166148 "Arginine vasopressin receptor 1A" P37288 12 63142759-63151201 "FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 53.5;blood vessel: 29.9" "Cell type enhanced" "Detected in some" "Adrenal cortex cells: 75.0;Decidual stromal cells: 40.9;Epididymal clear cells: 71.4;Hepatocytes: 73.5;Pericytes: 111.4;Platelets: 53.8;Vascular smooth muscle cells: 208.4" "Group enriched" "Detected in some" 6 "CGE interneuron: 5.1;hippocampal CA4: 3.3;LAMP5-LHX6 and Chandelier: 3.1;pericyte: 7.6;vascular associated smooth muscle cell: 9.6" "Cancer enriched" "Detected in many" 10 "Kidney Chromophobe (TCGA): 45.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 2.8;Neuroblastoma: 1.1" "Adrenal gland - Adrenal cortex cells, Breast - Endothelial cells, Liver - Hepatocytes, Minor Salivary Gland - Endothelial cells" "Group enriched" "Detected in some" 5 "basal ganglia: 7.0;hypothalamus: 3.8" "Low region specificity" "Detected in all" NA NA "Cluster 76: Non-specific - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 103: Non-specific - Basic cellular processes" 1 "unprognostic (1.30e-2)" "unprognostic (6.19e-2)" "unprognostic (3.22e-1)" "unprognostic (2.16e-1)" "unprognostic (1.98e-1)" "unprognostic (1.20e-1)" "validated prognostic favorable (4.85e-5)" "validated prognostic favorable (8.06e-5)" "unprognostic (5.33e-2)" "unprognostic (5.23e-2)" "unprognostic (1.15e-1)" "unprognostic (7.64e-3)" "unprognostic (4.14e-2)" "unprognostic (1.23e-2)" "unprognostic (6.29e-2)" "potential prognostic unfavorable (4.02e-6)" "unprognostic (2.52e-3)" "unprognostic (2.99e-2)" "unprognostic (2.37e-2)" AVPR1B "AVPR3, V1bR, VPR3" ENSG00000198049 "Arginine vasopressin receptor 1B" P47901 1 206106936-206117699 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 29 "pituitary gland: 13.8" "Cell type enriched" "Detected in some" 4 "Corticotrophs: 56.8" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Kidney Renal Clear Cell Carcinoma (TCGA): 3.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enteroendocrine cells, Kidney - Macrophages, Pancreas - Alpha cells, Pituitary gland - Corticotropes" "Not detected" "Not detected" "Not detected" "Not detected" HPA075404 Enhanced NA NA "Cluster 20: Pituitary gland - Hormone signaling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 51: Secretory epithelial cells - Mixed function" "HPA075404: " "validated prognostic favorable (1.65e-6)" "validated prognostic favorable (1.88e-4)" AVPR2 "DIR, DIR3, V2R" ENSG00000126895 "Arginine vasopressin receptor 2" P30518 X 153902531-153907166 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Diabetes insipidus, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 9.6;kidney: 12.5" "Group enriched" "Detected in some" 4 "Lymphatic endothelial cells: 11.7;Renal collecting duct principal cells: 15.2;Vascular endothelial cells: 16.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 5 "cerebellum: 9.3" "Group enriched" "Detected in some" 28 "intermediate monocyte: 3.5;non-classical monocyte: 3.2" "Lineage enriched" "Detected in single" 30 "monocytes: 3.5" "Cancer enhanced" "Detected in some" "Adrenocortical cancer: 5.3" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Ascending Loop of Henle cells, Prostate - Endothelial cells, Testis - Endothelial cells" "Not detected" "Not detected" "Region enriched" "Detected in single" 29 "cerebellum: 10.5" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 35: Non-specific - DNA binding" "Cluster 70: DU4475 - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 4 "unprognostic (4.28e-3)" "unprognostic (7.94e-2)" "unprognostic (4.18e-2)" "potential prognostic favorable (1.32e-4)" "unprognostic (3.13e-3)" "unprognostic (2.36e-3)" "unprognostic (2.86e-3)" "unprognostic (1.73e-1)" "unprognostic (2.55e-1)" "unprognostic (1.28e-1)" AWAT1 DGAT2L3 ENSG00000204195 "Acyl-CoA wax alcohol acyltransferase 1" Q58HT5 X 70234655-70240659 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "skin 1: 1.9" "Cell type enhanced" "Detected in some" "Adipocytes: 4.0;Goblet cells: 6.0;Hepatic stellate cells: 19.4;Medullary thymic epithelial cells: 7.2;Müller glia: 2.3;Myonuclei: 2.7;Sertoli cells: 2.2" "Cell type enhanced" "Detected in some" "Bergmann glia: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Sebaceous gland cells" "Not detected" "Not detected" HPA063412 Enhanced NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 27: Breast cancer - Unknown function" "Cluster 70: Intestinal goblet cells - Mucin production" "HPA063412: " AWAT2 "DGAT2L4, MFAT" ENSG00000147160 "Acyl-CoA wax alcohol acyltransferase 2" Q6E213 X 70040542-70049938 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "skin 1: 10.7" "Group enriched" "Detected in some" 5 "Early primary spermatocytes: 9.1;Medullary thymic epithelial cells: 4.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Sebaceous gland cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA062748 Approved NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 27: Breast cancer - Unknown function" "Cluster 3: Early primary spermatocytes - Early meiosis" "HPA062748: " AXDND1 "C1orf125, FLJ32940" ENSG00000162779 "Axonemal dynein light chain domain containing 1" Q5T1B0 1 179365720-179554735 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 33 "testis: 14.7" "Cell type enhanced" "Detected in many" "Early spermatids: 242.0;Ependymal cells: 92.5;Foveolar cells: 62.4;Late primary spermatocytes: 246.0;Late spermatids: 425.1" "Cell type enriched" "Detected in many" 5 "ependymal cell: 90.1" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Podocytes, Lung - Respiratory ciliated cells, Skin - Sebaceous gland cells, Stomach - Gastric mucous cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA071114 Enhanced Approved "Primary cilium,Basal body,Cytosol" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 3: Choroid plexus - Cilium" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" "Primary cilium, Cytosol" "Basal body" "HPA071114: " "unprognostic (2.41e-1)" "unprognostic (1.00e-2)" AXIN1 PPP1R49 ENSG00000103126 "Axin 1" O15169 16 287440-352723 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Wnt signaling pathway" "Developmental protein" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cells: 91.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012987, HPA056522" Approved Approved "Nucleoplasm,Nucleoli,Vesicles,Primary cilium,Primary cilium tip,Primary cilium transition zone" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 54: Non-specific - Transcription" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 93 "Nucleoplasm, Vesicles, Primary cilium" "Nucleoli, Primary cilium tip, Primary cilium transition zone" "CAB012987: , HPA056522: " "unprognostic (1.84e-1)" "unprognostic (7.52e-2)" "unprognostic (8.55e-2)" "unprognostic (2.54e-2)" "unprognostic (3.18e-1)" "unprognostic (3.92e-1)" "unprognostic (1.73e-1)" "unprognostic (1.88e-3)" "unprognostic (1.03e-1)" "unprognostic (3.25e-1)" "unprognostic (3.96e-1)" "unprognostic (1.67e-1)" "unprognostic (1.85e-1)" "validated prognostic unfavorable (1.43e-6)" "validated prognostic unfavorable (4.18e-4)" "unprognostic (8.18e-2)" "unprognostic (3.17e-2)" "unprognostic (3.47e-1)" "unprognostic (2.38e-3)" "unprognostic (9.14e-2)" "unprognostic (4.17e-1)" "unprognostic (2.23e-2)" "unprognostic (1.28e-1)" "unprognostic (1.17e-2)" "potential prognostic favorable (4.32e-4)" "unprognostic (8.32e-2)" "unprognostic (1.49e-1)" "unprognostic (3.22e-2)" "unprognostic (2.55e-1)" "unprognostic (2.58e-2)" "unprognostic (6.50e-2)" AXIN2 "DKFZp781B0869, MGC126582" ENSG00000168646 "Axin 2" Q9Y2T1 17 65528563-65561648 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Wnt signaling pathway" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bergmann glia: 34.3;Early spermatids: 35.3;Enteric stem cells: 34.1;Extravillous trophoblasts: 144.3;Migrating cytotrophoblasts: 42.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Colon Adenocarcinoma (TCGA): 74.0;Rectum Adenocarcinoma (TCGA): 77.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.2" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "colorectal cancer: 121.4;Gastric cancer: 86.5" "Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012283, CAB017783" Approved Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 75: Ovary - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 32: Non-specific - Cell proliferation" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 49 "Nucleoplasm, Plasma membrane, Cytosol" "CAB012283: , CAB017783: " "unprognostic (4.89e-2)" "unprognostic (7.61e-2)" "unprognostic (5.79e-1)" "unprognostic (4.65e-2)" "unprognostic (2.53e-1)" "unprognostic (2.68e-3)" "unprognostic (4.35e-1)" "unprognostic (5.35e-3)" "unprognostic (6.49e-2)" "unprognostic (1.76e-1)" "unprognostic (2.99e-1)" "unprognostic (4.92e-2)" "unprognostic (2.62e-2)" "unprognostic (5.32e-2)" "unprognostic (9.67e-2)" "unprognostic (2.35e-2)" "unprognostic (1.79e-2)" "unprognostic (4.29e-2)" "unprognostic (9.10e-2)" "unprognostic (1.72e-2)" "unprognostic (1.27e-1)" "unprognostic (6.11e-3)" "unprognostic (5.16e-2)" "unprognostic (3.28e-1)" "potential prognostic favorable (1.89e-4)" "unprognostic (1.58e-1)" "unprognostic (2.95e-2)" "unprognostic (1.82e-2)" "unprognostic (3.57e-1)" "unprognostic (1.88e-1)" "unprognostic (1.27e-3)" AXL "ARK, JTK11, Tyro7, UFO" ENSG00000167601 "AXL receptor tyrosine kinase" P30530 19 41219223-41261766 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins" "Differentiation, Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "FDA approved drug targets, Oncogene, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 293.9;Epididymal basal cells: 195.9;Fibro-adipogenic progenitors: 206.2;Fibroblasts: 236.4;Granulosa cells: 223.8;Hepatic stellate cells: 245.3;Kupffer cells: 591.4;Macrophages: 201.4;Pericytes: 323.7;Sertoli cells: 177.0;Vascular smooth muscle cells: 391.5" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 193.4;pericyte: 261.6;vascular associated smooth muscle cell: 197.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 11.3;plasmacytoid DC: 25.8" "Group enriched" "Detected in many" 12 "dendritic cells: 25.8;NK-cells: 11.3" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 812.7" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032501, HPA037422, HPA037423, HPA075217" Uncertain Supported "Vesicles,Plasma membrane,Actin filaments" NA Yes 6700000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 19: Astrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 103: Non-specific - Basic cellular processes" 26 "Plasma membrane" "Vesicles, Actin filaments" "CAB032501: , HPA037422: , HPA037423: , HPA075217: " "unprognostic (1.99e-1)" "unprognostic (1.61e-1)" "unprognostic (2.47e-1)" "unprognostic (3.47e-2)" "unprognostic (9.12e-3)" "unprognostic (1.19e-2)" "unprognostic (4.30e-1)" "unprognostic (1.15e-1)" "unprognostic (8.92e-3)" "unprognostic (1.85e-1)" "unprognostic (9.14e-2)" "unprognostic (8.04e-2)" "unprognostic (6.26e-3)" "unprognostic (1.99e-1)" "unprognostic (8.38e-3)" "unprognostic (1.08e-1)" "unprognostic (9.13e-3)" "unprognostic (6.41e-2)" "unprognostic (6.31e-2)" "unprognostic (2.05e-2)" "potential prognostic unfavorable (1.07e-5)" "unprognostic (9.85e-3)" "unprognostic (1.20e-2)" "unprognostic (1.90e-1)" "unprognostic (1.83e-1)" "unprognostic (1.06e-3)" "unprognostic (3.69e-2)" "unprognostic (3.56e-3)" "unprognostic (3.87e-2)" "unprognostic (9.23e-3)" "unprognostic (3.06e-2)" AZGP1 "ZA2G, ZAG" ENSG00000160862 "Alpha-2-glycoprotein 1, zinc-binding" P25311 7 99966720-99976042 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 2621.1;salivary gland: 3617.4" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 2494.0;Hepatocytes: 5184.7;Lacrimal acinar cells: 7814.6;Prostatic club cells: 1114.4;Prostatic glandular cells: 4092.7;Salivary acinar cells: 4571.1;Salivary duct cells: 949.0;Salivary myoepithelial cells: 1409.4" "Group enriched" "Detected in some" 6 "Bergmann glia: 3.2;choroid plexus epithelial cell: 3.1;committed oligodendrocyte precursor: 5.1;oligodendrocyte: 11.4;oligodendrocyte precursor cell: 3.9" "Group enriched" "Detected in many" 10 "Breast Invasive Carcinoma (TCGA): 1562.4;Liver Hepatocellular Carcinoma (TCGA): 857.6;Prostate Adenocarcinoma (TCGA): 1716.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 226.3;prostate cancer: 78.4" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Breast glandular cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Stomach - Chief cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA012582, HPA012876, CAB016087, CAB032276" Enhanced Approved Nucleoplasm,Vesicles "Secreted to blood" "No annotated function" NA NA 55200000000 17000000000 "Cluster 70: Non-specific - Protein processing" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 31 Vesicles Nucleoplasm "CAB016087: , CAB032276: , HPA012582: , HPA012876: " "unprognostic (2.60e-3)" "unprognostic (1.70e-1)" "unprognostic (2.48e-1)" "unprognostic (1.49e-1)" "unprognostic (2.19e-1)" "unprognostic (1.01e-1)" "unprognostic (1.15e-2)" "unprognostic (3.67e-2)" "unprognostic (1.88e-2)" "unprognostic (2.28e-1)" "potential prognostic favorable (2.53e-4)" "unprognostic (3.62e-2)" "unprognostic (1.32e-2)" "unprognostic (1.39e-3)" "unprognostic (1.30e-2)" "unprognostic (4.84e-2)" "unprognostic (6.17e-3)" "unprognostic (7.89e-3)" "unprognostic (1.33e-1)" "unprognostic (1.85e-1)" "unprognostic (2.48e-1)" "unprognostic (2.78e-2)" "unprognostic (1.50e-1)" "unprognostic (2.71e-1)" "unprognostic (8.77e-2)" "unprognostic (1.79e-1)" "unprognostic (4.35e-2)" "unprognostic (2.14e-1)" "unprognostic (1.56e-1)" "unprognostic (6.31e-2)" AZI2 "AZ2, FLJ21939, NAP1" ENSG00000163512 "5-azacytidine induced 2" Q9H6S1 3 28315003-28349050 "Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 241.9;Neutrophils: 235.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035258 Approved NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 73: Brain - Neuronal signaling" "Cluster 21: Non-specific - Metabolism" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 15 "HPA035258: " "unprognostic (1.94e-2)" "unprognostic (3.09e-2)" "unprognostic (1.09e-2)" "unprognostic (4.45e-2)" "unprognostic (2.96e-1)" "unprognostic (1.64e-2)" "unprognostic (2.52e-1)" "potential prognostic unfavorable (4.10e-6)" "unprognostic (6.80e-2)" "unprognostic (2.04e-2)" "potential prognostic favorable (9.15e-5)" "unprognostic (1.42e-1)" "unprognostic (9.22e-2)" "potential prognostic unfavorable (4.81e-6)" "unprognostic (2.48e-2)" "unprognostic (2.57e-1)" "unprognostic (1.82e-2)" "unprognostic (1.20e-1)" "unprognostic (2.44e-1)" "unprognostic (2.75e-1)" "unprognostic (4.73e-2)" "unprognostic (1.31e-1)" "unprognostic (3.82e-3)" "unprognostic (1.19e-1)" "unprognostic (1.52e-2)" "unprognostic (3.55e-3)" "unprognostic (2.58e-1)" "unprognostic (1.20e-1)" "unprognostic (2.41e-1)" "unprognostic (5.90e-2)" "unprognostic (4.79e-2)" AZIN1 "OAZI, OAZIN, ODC1L" ENSG00000155096 "Antizyme inhibitor 1" O14977 8 102826111-102893864 "Predicted intracellular proteins" "Polyamine biosynthesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 990.2;Syncytiotrophoblasts: 448.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026102, HPA027948" Approved Approved "Nucleoli,Nucleoli rim" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 27: Non-specific - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 7 "Nucleoli, Nucleoli rim" "HPA026102: , HPA027948: " "unprognostic (1.13e-1)" "unprognostic (9.43e-3)" "unprognostic (3.44e-3)" "unprognostic (2.34e-3)" "unprognostic (3.00e-1)" "unprognostic (6.20e-3)" "unprognostic (2.47e-1)" "unprognostic (2.23e-1)" "unprognostic (4.20e-3)" "unprognostic (1.64e-2)" "potential prognostic favorable (7.53e-6)" "unprognostic (1.04e-1)" "potential prognostic unfavorable (2.82e-4)" "unprognostic (5.37e-2)" "unprognostic (5.38e-3)" "unprognostic (1.33e-2)" "unprognostic (1.23e-2)" "unprognostic (4.48e-2)" "unprognostic (1.18e-1)" "unprognostic (3.02e-2)" "unprognostic (9.12e-2)" "unprognostic (1.24e-3)" "potential prognostic unfavorable (2.28e-4)" "unprognostic (2.32e-3)" "unprognostic (1.51e-1)" "unprognostic (1.99e-1)" "unprognostic (1.50e-1)" "unprognostic (3.98e-1)" "unprognostic (3.52e-1)" "unprognostic (2.06e-2)" "unprognostic (1.48e-1)" AZIN2 "ADC, KIAA1945, ODC-p, ODC1L, ODCp" ENSG00000142920 "Antizyme inhibitor 2" Q96A70 1 33081104-33123492 "Metabolic proteins, Predicted intracellular proteins" "Polyamine biosynthesis, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 21.7;testis: 29.6" "Cell type enriched" "Detected in many" 4 "Late spermatids: 1545.9" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 225.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "basophil: 6.5;plasmacytoid DC: 18.9" "Group enriched" "Detected in many" 8 "dendritic cells: 18.9;granulocytes: 6.5" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Adipose progenitor cells, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028527 Approved Cytosol NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 61: BICR 18 - Protein kinases" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 3 Cytosol "HPA028527: " "unprognostic (1.04e-1)" "unprognostic (2.06e-1)" "unprognostic (9.91e-2)" "unprognostic (3.42e-2)" "unprognostic (1.22e-1)" "unprognostic (4.27e-1)" "unprognostic (1.25e-2)" "unprognostic (2.85e-1)" "unprognostic (1.57e-1)" "potential prognostic favorable (1.10e-8)" "unprognostic (1.25e-2)" "unprognostic (1.64e-1)" "unprognostic (1.83e-2)" "unprognostic (2.61e-1)" "unprognostic (2.65e-1)" "unprognostic (1.03e-1)" "unprognostic (6.51e-2)" "unprognostic (6.45e-2)" "unprognostic (4.49e-2)" "unprognostic (2.72e-1)" "unprognostic (5.02e-1)" "unprognostic (4.33e-2)" "unprognostic (2.70e-1)" "unprognostic (1.56e-2)" "unprognostic (1.95e-1)" "unprognostic (6.15e-2)" "unprognostic (1.49e-1)" AZU1 "AZAMP, AZU, CAP37, HBP, HUMAZUR, NAZC" ENSG00000172232 "Azurocidin 1" P20160 19 825097-832018 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Chemotaxis "Antibiotic, Antimicrobial, Heparin-binding, Serine protease homolog" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 46 "bone marrow: 1507.5" "Group enriched" "Detected in some" 65 "Monocyte progenitors: 423.6;Neutrophil progenitors: 473.3" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 1.6" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 9 "neutrophil: 3.3" "Lineage enriched" "Detected in single" 9 "granulocytes: 3.3" "Cancer enriched" "Detected in single" 40 "Leukemia: 39.1" "Breast - Breast glandular cells, Liver - Erythroid cells, Lung - Neutrophils_1, Spleen - Neutrophils_1" "Not detected" "Not detected" "HPA055851, HPA075964" Enhanced Enhanced Vesicles "Secreted to blood" Defense NA NA 13700000 7000000 "Cluster 4: Neutrophils - Degranulation" "Cluster 15: Bone marrow - Innate immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 7 Vesicles "HPA055851: , HPA075964: " "unprognostic (3.70e-2)" "unprognostic (4.95e-2)" "unprognostic (1.00e-1)" B2M ENSG00000166710 Beta-2-microglobulin P61769 15 44711358-44718851 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" Immunity "Amyloidosis, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "cDC: 3645.2;Decidual stromal cells: 4907.0;Enterocytes: 5902.7;Kupffer cells: 5841.0;Plasma cells: 3861.8;Platelets: 5107.2;Suprabasal keratinocytes: 3628.6;T-cells: 3310.0" "Cell type enhanced" "Detected in all" "endothelial cell: 2406.5;leukocyte: 2950.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002572, HPA006361" Enhanced Enhanced "Golgi apparatus,Plasma membrane,Cytosol" "Secreted to blood" Immunity NA NA 1790000000 1300000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 8: Immune cells - Immune response" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 67: Plasma cells - Plasma cell differentiation" 30 "Golgi apparatus, Plasma membrane" Cytosol "CAB002572: , HPA006361: " "unprognostic (6.33e-2)" "unprognostic (1.23e-1)" "unprognostic (1.58e-1)" "unprognostic (1.73e-1)" "unprognostic (7.87e-2)" "unprognostic (2.69e-2)" "unprognostic (3.85e-1)" "unprognostic (2.75e-1)" "unprognostic (2.00e-1)" "unprognostic (2.22e-1)" "potential prognostic favorable (2.28e-4)" "unprognostic (8.66e-2)" "unprognostic (1.10e-1)" "unprognostic (6.29e-2)" "unprognostic (2.34e-2)" "unprognostic (1.01e-1)" "unprognostic (1.29e-1)" "unprognostic (2.75e-1)" "unprognostic (2.34e-1)" "unprognostic (3.02e-1)" "unprognostic (1.35e-1)" "unprognostic (6.76e-3)" "unprognostic (7.86e-2)" "unprognostic (4.18e-2)" "unprognostic (4.20e-1)" "unprognostic (1.68e-1)" "unprognostic (6.18e-2)" "unprognostic (1.86e-1)" "unprognostic (3.40e-2)" "unprognostic (2.76e-2)" "unprognostic (1.13e-1)" B3GALNT1 "B3GALANT1, B3GALT3, beta3Gal-T3, galT3, GLOB" ENSG00000169255 "Beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)" O75752 3 161083883-161105411 "Blood group antigen proteins, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" "Blood group antigen, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 49.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 138.1;Other brain neurons: 50.9;Parietal cells: 60.1;Retinal bipolar cells: 60.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "basophil: 8.8;NK-cell: 22.1" "Group enriched" "Detected in many" 7 "granulocytes: 8.8;NK-cells: 22.1" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Pituitary gland - Undifferentiated cells (Pituitary gland), Spleen - Endothelial cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041204 Approved Vesicles NA NA 270000 "Cluster 32: Basophils - Transcription" "Cluster 35: Non-specific - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" Vesicles "HPA041204: " "potential prognostic favorable (3.73e-4)" "unprognostic (3.89e-2)" "unprognostic (2.62e-1)" "unprognostic (4.34e-2)" "unprognostic (2.10e-1)" "unprognostic (2.47e-2)" "unprognostic (1.06e-2)" "unprognostic (1.58e-1)" "unprognostic (5.56e-2)" "unprognostic (2.64e-1)" "validated prognostic favorable (5.12e-7)" "validated prognostic favorable (3.81e-4)" "unprognostic (1.43e-2)" "potential prognostic unfavorable (9.24e-5)" "unprognostic (4.05e-3)" "unprognostic (1.07e-2)" "unprognostic (1.29e-2)" "unprognostic (7.14e-2)" "unprognostic (2.79e-1)" "unprognostic (2.16e-1)" "unprognostic (1.40e-3)" "unprognostic (5.08e-2)" "unprognostic (1.60e-1)" "unprognostic (1.07e-1)" "unprognostic (3.33e-2)" "unprognostic (2.91e-2)" "unprognostic (2.76e-3)" "unprognostic (3.57e-2)" "unprognostic (8.94e-2)" "unprognostic (2.09e-2)" "unprognostic (1.92e-1)" B3GALNT2 MGC39558 ENSG00000162885 "Beta-1,3-N-acetylgalactosaminyltransferase 2" Q8NCR0 1 235447190-235504452 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 69.6;Bergmann glia: 61.6;Brain excitatory neurons: 54.0;Brain inhibitory neurons: 61.0;Choroid plexus epithelial cells: 110.1;Distal convoluted tubule cells: 67.9;Ependymal cells: 45.8;Loop of henle epithelial cells: 44.5;Microglia: 46.5;Oligodendrocyte progenitor cells: 47.5;Other brain neurons: 51.5;Proximal tubule cells: 37.4;Renal collecting duct intercalated cells: 52.1;Renal connecting tubule cells: 61.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007846, HPA050662" Approved Uncertain "Golgi apparatus" "Intracellular and membrane" Enzyme NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 24: Non-specific - Transcription" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 45: Non-specific - Nuclear processes" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" 2 "Golgi apparatus" "HPA007846: , HPA050662: " "unprognostic (1.05e-2)" "unprognostic (6.52e-2)" "unprognostic (9.76e-3)" "unprognostic (2.86e-2)" "unprognostic (6.60e-2)" "unprognostic (4.26e-2)" "unprognostic (6.44e-2)" "unprognostic (2.77e-2)" "unprognostic (8.16e-2)" "unprognostic (8.10e-2)" "unprognostic (2.56e-2)" "unprognostic (9.46e-2)" "unprognostic (1.52e-3)" "unprognostic (3.77e-2)" "unprognostic (1.13e-1)" "unprognostic (1.71e-1)" "unprognostic (9.68e-2)" "unprognostic (3.74e-2)" "unprognostic (1.03e-2)" "unprognostic (6.17e-2)" "unprognostic (7.63e-3)" "unprognostic (8.70e-2)" "unprognostic (1.48e-1)" "unprognostic (3.26e-1)" "unprognostic (2.71e-2)" "unprognostic (1.40e-1)" "unprognostic (2.84e-2)" "unprognostic (1.21e-1)" "unprognostic (1.65e-2)" "unprognostic (9.04e-3)" "unprognostic (9.44e-2)" B3GALT1 beta3Gal-T1 ENSG00000172318 "Beta-1,3-galactosyltransferase 1" Q9Y5Z6 2 167293001-167874045 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.3;skeletal muscle: 4.3;tongue: 14.8" "Cell type enriched" "Detected in many" 4 "Pituicytes/FSCs: 1520.3" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 3.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 3.0" "Adrenal gland - Adrenal medulla cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 51: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" "potential prognostic favorable (7.58e-4)" "unprognostic (1.11e-1)" "unprognostic (4.03e-2)" "unprognostic (9.59e-3)" "unprognostic (2.21e-1)" B3GALT2 beta3Gal-T2 ENSG00000162630 "Beta-1,3-galactosyltransferase 2" O43825 1 193178730-193186613 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 15.3;gallbladder: 14.1;heart muscle: 19.7" "Cell type enhanced" "Detected in many" "Adipocytes: 14.5;Brain excitatory neurons: 14.7;Brain inhibitory neurons: 19.8;Cardiomyocytes: 43.4;Epicardial cells: 50.0;Leydig cells: 33.6;Oligodendrocyte progenitor cells: 20.4;Other brain neurons: 20.3;Peritubular myoid cells: 19.4;Retinal amacrine cells: 13.2;Retinal bipolar cells: 34.1" "Cell type enhanced" "Detected in many" "deep-layer corticothalamic and 6b: 116.5;LAMP5-LHX6 and Chandelier: 114.7" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 3.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "MAIT T-cell: 8.4" "Lineage enriched" "Detected in single" 53 "T-cells: 8.4" "Cancer enhanced" "Detected in some" "pancreatic cancer: 3.5" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078659 Approved "Plasma membrane" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 35: Non-specific - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 1 "Plasma membrane" "HPA078659: " "unprognostic (3.37e-1)" "unprognostic (1.81e-1)" "unprognostic (3.07e-1)" "unprognostic (1.28e-2)" "unprognostic (2.69e-2)" "validated prognostic favorable (1.12e-4)" "validated prognostic favorable (8.30e-4)" "potential prognostic favorable (1.27e-4)" "unprognostic (2.38e-1)" "unprognostic (1.37e-2)" "unprognostic (7.60e-2)" B3GALT4 "beta3Gal-T4, GalT4" ENSG00000235863 "Beta-1,3-galactosyltransferase 4" O96024 6 33277123-33284832 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 26.4" "Cell type enhanced" "Detected in some" "Bergmann glia: 6.5;Brain excitatory neurons: 5.2;Brain inhibitory neurons: 3.3;Ependymal cells: 5.7;Loop of henle epithelial cells: 5.5;Microglia: 7.2;Oligodendrocyte progenitor cells: 3.6;Oligodendrocytes: 6.2;Other brain neurons: 5.5;Papillary tip epithelial cells: 14.6;Podocytes: 13.7;Renal collecting duct intercalated cells: 4.0;Renal collecting duct principal cells: 11.2;Renal connecting tubule cells: 3.8" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in some" 10 "Ovary Serous Cystadenocarcinoma (TCGA): 5.8;Stomach Adenocarcinoma (TCGA): 5.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043001 Approved NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 25: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 98: Neurons - Neurotransmission & signaling" 15 "HPA043001: " "unprognostic (3.62e-3)" "unprognostic (1.59e-1)" "unprognostic (2.05e-1)" "unprognostic (4.65e-2)" "unprognostic (2.57e-2)" "unprognostic (6.08e-3)" "unprognostic (4.69e-2)" "unprognostic (2.12e-1)" "unprognostic (6.85e-2)" "unprognostic (1.47e-1)" B3GALT5 "B3GalT-V, B3T5, beta3Gal-T5, GLCT5" ENSG00000183778 "Beta-1,3-galactosyltransferase 5" Q9Y2C3 21 39556442-39673137 "Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "intestine: 42.8" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 31.9;Brain inhibitory neurons: 37.5;Choroid plexus epithelial cells: 80.6;Ependymal cells: 50.7;Other brain neurons: 31.2;Papillary tip epithelial cells: 68.8;Pituitary stem cells: 74.7;Renal collecting duct principal cells: 42.3;Somatotrophs: 63.6;Thyrotrophs: 69.1" "Cell type enhanced" "Detected in many" "medium spiny neuron: 80.8" "Cancer enhanced" "Detected in many" "Pancreatic Adenocarcinoma (TCGA): 10.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 11.1;pancreatic cancer: 14.9" "Adrenal gland - Adrenal medulla cells, Breast - Breast glandular cells (progenitors), Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Prostate - Urothelial cells, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 11.4" "HPA054092, HPA054684" Approved "Intracellular and membrane" Enzyme NA NA "Cluster 77: Intestine - Digestion" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Neurons - Synaptic function & neurogenesis" 2 "HPA054092: , HPA054684: " "unprognostic (1.09e-1)" "unprognostic (6.85e-2)" "unprognostic (7.17e-2)" "unprognostic (2.23e-2)" "unprognostic (7.45e-2)" "unprognostic (2.64e-2)" "unprognostic (3.30e-2)" "unprognostic (8.87e-3)" "unprognostic (6.00e-2)" "unprognostic (1.88e-1)" "potential prognostic unfavorable (6.95e-4)" "unprognostic (7.72e-2)" "unprognostic (1.64e-1)" "unprognostic (8.85e-3)" "unprognostic (9.17e-2)" "unprognostic (4.46e-1)" "unprognostic (6.07e-2)" B3GALT6 beta3GalT6 ENSG00000176022 "Beta-1,3-galactosyltransferase 6" Q96L58 1 1232237-1235041 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Disease variant, Dwarfism, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 12000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 17: Non-specific - RNA processing" 5 "unprognostic (2.14e-1)" "unprognostic (2.53e-1)" "unprognostic (1.68e-2)" "unprognostic (3.44e-2)" "unprognostic (4.04e-2)" "unprognostic (1.44e-2)" "unprognostic (1.01e-1)" "unprognostic (1.74e-3)" "unprognostic (8.77e-2)" "unprognostic (2.17e-1)" "unprognostic (6.69e-2)" "unprognostic (1.31e-1)" "potential prognostic favorable (4.34e-5)" "validated prognostic unfavorable (4.55e-4)" "validated prognostic unfavorable (1.61e-4)" "unprognostic (1.48e-1)" "unprognostic (1.08e-1)" "unprognostic (4.56e-2)" "unprognostic (1.97e-1)" "unprognostic (8.07e-2)" "unprognostic (2.84e-1)" "unprognostic (1.08e-1)" "unprognostic (1.90e-1)" "unprognostic (1.82e-2)" "unprognostic (3.56e-2)" "unprognostic (2.09e-2)" "unprognostic (1.80e-1)" "unprognostic (3.17e-1)" "unprognostic (6.28e-2)" "unprognostic (2.55e-1)" "unprognostic (3.18e-1)" B3GALT9 B3GNT10 ENSG00000214654 "Beta-1,3-galactosyltransferase 9" A8MXE2 9 120792403-120801787 "Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 14.7;Cardiomyocytes: 60.7;Early spermatids: 18.1;Epicardial cells: 29.6;Late spermatids: 47.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 40: Non-specific - Mixed function" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "unprognostic (7.21e-2)" "unprognostic (7.27e-3)" "unprognostic (1.02e-1)" "unprognostic (1.49e-1)" "unprognostic (8.45e-2)" "unprognostic (2.08e-1)" "unprognostic (2.31e-1)" "unprognostic (2.48e-1)" "unprognostic (3.83e-3)" "validated prognostic favorable (3.59e-9)" "validated prognostic favorable (7.32e-5)" "unprognostic (2.60e-1)" "unprognostic (5.05e-2)" "unprognostic (2.21e-2)" "unprognostic (1.20e-2)" "unprognostic (9.16e-2)" "unprognostic (2.74e-1)" "unprognostic (5.77e-2)" "unprognostic (8.82e-2)" "unprognostic (4.47e-2)" "unprognostic (1.76e-1)" "potential prognostic favorable (7.26e-4)" "unprognostic (7.72e-2)" "unprognostic (2.75e-1)" "unprognostic (2.21e-2)" "unprognostic (8.38e-2)" "unprognostic (1.03e-1)" "unprognostic (1.19e-2)" B3GAT1 "CD57, GlcAT-P, HNK-1, LEU7, NK-1" ENSG00000109956 "Beta-1,3-glucuronyltransferase 1" Q9P2W7 11 134378504-134412242 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 191.4" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 42.5;Astrocytes: 42.1;Bergmann glia: 51.7;Brain excitatory neurons: 52.6;Brain inhibitory neurons: 37.2;Gastric chief cells: 45.9;Müller glia: 144.8;Oligodendrocyte progenitor cells: 73.7;Oligodendrocytes: 120.5;Retinal amacrine cells: 32.4;Retinal bipolar cells: 29.1" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" 8 "Glioblastoma Multiforme (TCGA): 52.3;Prostate Adenocarcinoma (TCGA): 14.0;Thyroid Carcinoma (TCGA): 16.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.1" "Lineage enriched" "Detected in single" 12 "T-cells: 1.1" "Cancer enhanced" "Detected in many" "Neuroblastoma: 8.1" "Adrenal gland - Adrenal medulla cells, Heart muscle - T-cells, Stomach - Chief cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002500, CAB010893, HPA069468, HPA074314" Enhanced Enhanced Vesicles "Secreted in brain" Enzyme NA NA "Cluster 24: Non-specific - Transcription" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 51: Neurons - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 35: Neurons - Synaptic function & neurogenesis" 2 Vesicles "CAB002500: , CAB010893: , HPA069468: , HPA074314: " "potential prognostic favorable (9.10e-4)" "unprognostic (6.80e-3)" "unprognostic (4.21e-1)" "unprognostic (7.22e-2)" "unprognostic (1.35e-1)" "unprognostic (2.33e-2)" "unprognostic (9.43e-3)" "unprognostic (1.08e-3)" "unprognostic (2.66e-2)" "unprognostic (2.36e-1)" "unprognostic (1.90e-1)" "unprognostic (1.30e-1)" "potential prognostic favorable (4.17e-4)" "unprognostic (2.32e-1)" "unprognostic (1.43e-1)" "unprognostic (9.80e-2)" "unprognostic (1.12e-1)" "unprognostic (5.13e-2)" "unprognostic (7.97e-2)" B3GAT2 GlcAT-S ENSG00000112309 "Beta-1,3-glucuronyltransferase 2" Q9NPZ5 6 70856679-70957060 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "brain: 15.0;retina: 17.0" "Cell type enhanced" "Detected in many" "Astrocytes: 70.4;Ependymal cells: 63.3;Oligodendrocyte progenitor cells: 100.0;Oocytes: 73.7;Retinal horizontal cells: 372.6" "Cell type enhanced" "Detected in all" "hippocampal CA4: 301.8" "Group enriched" "Detected in some" 19 "Glioblastoma Multiforme (TCGA): 12.7;Prostate Adenocarcinoma (TCGA): 7.8;Testicular Germ Cell Tumor (TCGA): 3.6;Uterine Corpus Endometrial Carcinoma (TCGA): 6.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 2.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012059 Uncertain NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 109: Neurons - Neuronal signaling" 9 "HPA012059: " "unprognostic (1.56e-1)" "unprognostic (2.36e-1)" "unprognostic (1.03e-1)" "unprognostic (3.62e-3)" "unprognostic (9.28e-2)" "unprognostic (5.25e-2)" "unprognostic (1.73e-2)" "unprognostic (1.03e-1)" B3GAT3 GlcAT-I ENSG00000149541 "Beta-1,3-glucuronyltransferase 3" O94766 11 62615296-62622154 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Transferase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051328 Approved NA NA 75000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 45: Non-specific - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 57 "HPA051328: " "unprognostic (8.68e-2)" "unprognostic (1.49e-1)" "unprognostic (8.67e-2)" "unprognostic (1.06e-1)" "unprognostic (2.30e-2)" "unprognostic (1.85e-1)" "potential prognostic unfavorable (9.13e-4)" "unprognostic (3.18e-1)" "unprognostic (2.64e-2)" "unprognostic (1.91e-1)" "potential prognostic unfavorable (1.51e-7)" "unprognostic (2.55e-2)" "unprognostic (7.29e-2)" "potential prognostic unfavorable (3.34e-7)" "unprognostic (4.24e-3)" "unprognostic (2.34e-1)" "unprognostic (3.86e-2)" "unprognostic (4.59e-2)" "unprognostic (3.93e-1)" "unprognostic (2.77e-2)" "unprognostic (7.11e-2)" "unprognostic (3.16e-3)" "unprognostic (1.83e-1)" "unprognostic (1.61e-1)" "unprognostic (9.94e-2)" "unprognostic (2.51e-1)" "unprognostic (2.76e-2)" "unprognostic (7.41e-3)" "unprognostic (5.71e-2)" "unprognostic (2.24e-1)" "unprognostic (9.14e-2)" B3GLCT "B3GALTL, B3Glc-T, B3GTL" ENSG00000187676 "Beta 3-glucosyltransferase" Q6Y288 13 31199975-31332276 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Fucose metabolism" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 129.3;Cardiomyocytes: 115.4;Choroid plexus epithelial cells: 115.7;Cone photoreceptor cells: 178.0;Ependymal cells: 214.6;Retinal ganglion cells: 123.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Heart muscle - Cardiomyocytes, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" Enzyme NA NA "Cluster 1: T-cells - Unknown function" "Cluster 35: Non-specific - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 35: Neurons - Synaptic function & neurogenesis" 1 "unprognostic (5.68e-3)" "unprognostic (2.60e-1)" "unprognostic (4.52e-2)" "unprognostic (9.73e-2)" "unprognostic (6.45e-2)" "unprognostic (2.15e-2)" "unprognostic (4.76e-1)" "unprognostic (1.94e-1)" "unprognostic (1.20e-2)" "potential prognostic favorable (9.59e-8)" "unprognostic (9.06e-3)" "unprognostic (1.93e-3)" "unprognostic (8.89e-2)" "unprognostic (2.12e-2)" "unprognostic (4.26e-1)" "unprognostic (2.10e-1)" "unprognostic (2.00e-1)" "unprognostic (3.35e-2)" "unprognostic (1.07e-2)" "unprognostic (2.93e-3)" "unprognostic (2.56e-2)" "unprognostic (6.14e-2)" "unprognostic (2.09e-1)" "unprognostic (3.42e-2)" "unprognostic (6.43e-2)" "unprognostic (3.55e-1)" "unprognostic (5.07e-2)" "unprognostic (1.33e-1)" "unprognostic (2.11e-1)" B3GNT2 "B3GN-T1, B3GN-T2, B3GNT-2, B3GNT1, BETA3GNT" ENSG00000170340 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2" Q9NY97 2 62196115-62224731 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial luminal cells: 153.6;Esophageal apical cells: 154.8;Respiratory ionocytes: 175.3;Salivary ionocytes: 158.1" "Cell type enhanced" "Detected in all" "pericyte: 90.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 1, Minor Salivary Gland - Minor salivary gland basal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005997 Approved Approved Vesicles NA NA 23000000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 33: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 103: Non-specific - Basic cellular processes" 15 Vesicles "HPA005997: " "unprognostic (3.76e-2)" "unprognostic (3.46e-2)" "unprognostic (4.02e-1)" "unprognostic (9.57e-2)" "unprognostic (5.43e-2)" "unprognostic (3.57e-1)" "unprognostic (2.86e-1)" "unprognostic (8.90e-2)" "unprognostic (1.83e-1)" "unprognostic (1.35e-1)" "potential prognostic favorable (4.98e-8)" "unprognostic (5.38e-3)" "unprognostic (1.07e-2)" "unprognostic (4.46e-2)" "unprognostic (6.72e-2)" "unprognostic (1.78e-1)" "unprognostic (1.04e-1)" "unprognostic (3.48e-2)" "unprognostic (4.86e-2)" "unprognostic (9.92e-2)" "unprognostic (7.16e-3)" "potential prognostic unfavorable (6.80e-5)" "unprognostic (1.73e-1)" "unprognostic (1.45e-1)" "unprognostic (1.93e-1)" "unprognostic (3.95e-1)" "unprognostic (1.84e-2)" "unprognostic (2.12e-1)" "unprognostic (1.83e-1)" "unprognostic (4.17e-2)" "unprognostic (3.59e-1)" B3GNT3 "B3GN-T3, B3GNT-3, beta3Gn-T3, HP10328, TMEM3" ENSG00000179913 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3" Q9Y2A9 19 17794828-17813576 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 41.3;salivary gland: 26.3;stomach 1: 40.7" "Cell type enhanced" "Detected in many" "Cholangiocytes: 62.9;Colonocytes: 122.5;Cytotrophoblasts: 114.9;Enterocytes: 96.9;Esophageal apical cells: 217.0;Foveolar cells: 110.1;Goblet cells: 72.1;Migrating cytotrophoblasts: 51.1;Papillary tip epithelial cells: 60.6;Prostatic club cells: 51.1;Prostatic hillock cells: 60.4;Syncytiotrophoblasts: 88.6;Urothelial cells: 70.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "pancreatic cancer: 64.9" "Breast - Breast glandular cells (progenitors), Colon - Colon enterocytes, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Urothelial cells, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA024298 Enhanced "Intracellular and membrane" Enzyme NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 17: Intestine - Digestion" "Cluster 35: Non-specific - DNA binding" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 84: Apical squamous epithelium - Cornification" 41 "HPA024298: " "unprognostic (4.52e-3)" "unprognostic (5.59e-2)" "unprognostic (1.19e-1)" "unprognostic (1.09e-1)" "unprognostic (2.84e-1)" "unprognostic (7.83e-2)" "unprognostic (7.52e-2)" "unprognostic (1.03e-3)" "unprognostic (3.40e-2)" "unprognostic (3.86e-2)" "unprognostic (6.45e-2)" "unprognostic (3.40e-3)" "potential prognostic unfavorable (2.11e-4)" "unprognostic (2.26e-1)" "unprognostic (1.04e-2)" "unprognostic (5.09e-2)" "unprognostic (2.87e-2)" "unprognostic (3.56e-2)" "potential prognostic unfavorable (4.33e-5)" "unprognostic (1.48e-1)" "unprognostic (1.38e-1)" "unprognostic (1.23e-2)" "unprognostic (3.00e-1)" "unprognostic (2.78e-1)" "unprognostic (7.04e-2)" "unprognostic (1.60e-1)" "unprognostic (7.52e-2)" "unprognostic (1.27e-1)" B3GNT4 "B3GN-T4, beta3Gn-T4" ENSG00000176383 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4" Q9C0J1 12 122203681-122208952 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.9;skin 1: 2.6" "Cell type enriched" "Detected in some" 10 "Oocytes: 165.8" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Prostate Adenocarcinoma (TCGA): 15.3;Uterine Corpus Endometrial Carcinoma (TCGA): 25.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Kidney - Proximal tubular cells, Pituitary gland - Corticotropes, Skin - Keratinocyte (other)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA055261 Uncertain Approved Nucleoli,Mitochondria NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 34: Non-specific - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 41: Oocytes - Oogenesis" Mitochondria Nucleoli "HPA055261: " "unprognostic (2.07e-2)" "unprognostic (2.30e-1)" "unprognostic (9.16e-2)" "unprognostic (1.71e-1)" "unprognostic (1.78e-2)" "unprognostic (1.30e-2)" "unprognostic (4.37e-3)" "unprognostic (3.73e-2)" "unprognostic (3.25e-2)" "unprognostic (2.74e-2)" "unprognostic (8.34e-2)" "unprognostic (1.22e-1)" "unprognostic (6.11e-3)" "unprognostic (1.87e-1)" "unprognostic (2.89e-1)" "unprognostic (5.17e-1)" "unprognostic (5.69e-2)" B3GNT5 "B3GN-T5, beta3Gn-T5" ENSG00000176597 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5" Q9BYG0 3 183253253-183298504 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Developmental protein, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 72.3" "Cell type enhanced" "Detected in many" "Colonocytes: 305.9;Esophageal apical cells: 652.4;Esophageal suprabasal cells: 342.1;Microglia: 316.1;Neutrophils: 584.1;Ocular epithelial cells: 442.4;Syncytiotrophoblasts: 320.7;Urothelial cells: 382.4" "Cell type enriched" "Detected in all" 4 "central nervous system macrophage: 360.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "neutrophil: 5.6" "Lineage enriched" "Detected in many" 6 "granulocytes: 5.6" "Low cancer specificity" "Detected in many" "Prostate - Urothelial cells, Stomach - Gastric mucous cells, Testis - Early spermatids" "Region enriched" "Detected in many" 4 "cerebellum: 14.7" "Low region specificity" "Detected in all" HPA017292 Uncertain Approved Nucleoli NA NA 13000 "Cluster 21: Neutrophils - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 2 Nucleoli "HPA017292: " "unprognostic (2.42e-1)" "unprognostic (2.68e-1)" "unprognostic (2.26e-1)" "unprognostic (2.52e-1)" "unprognostic (1.30e-2)" "potential prognostic favorable (3.32e-5)" "unprognostic (3.12e-1)" "potential prognostic unfavorable (6.82e-5)" "unprognostic (1.82e-2)" "unprognostic (8.69e-3)" "unprognostic (8.50e-2)" "unprognostic (3.29e-1)" "unprognostic (8.98e-3)" "unprognostic (3.74e-3)" "unprognostic (1.34e-1)" "validated prognostic unfavorable (1.18e-4)" "validated prognostic unfavorable (5.98e-5)" "unprognostic (4.79e-2)" "unprognostic (1.99e-2)" "unprognostic (2.42e-1)" "unprognostic (3.42e-1)" "validated prognostic unfavorable (4.15e-4)" "validated prognostic unfavorable (2.55e-4)" "unprognostic (2.90e-1)" "unprognostic (1.53e-1)" "unprognostic (2.60e-2)" "unprognostic (2.26e-1)" "unprognostic (5.37e-2)" "unprognostic (1.79e-1)" "unprognostic (2.85e-2)" "unprognostic (1.04e-3)" B3GNT6 B3Gn-T6 ENSG00000198488 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6" Q6ZMB0 11 77034398-77041973 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 20.4;salivary gland: 6.3;stomach 1: 23.5" "Cell type enriched" "Detected in some" 4 "Goblet cells: 92.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Lung Adenocarcinoma (TCGA): 10.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 1.3;lung cancer: 1.8" "Colon - Colon enterocytes, Minor Salivary Gland - Minor salivary glandular cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA039805 Enhanced "Intracellular and membrane" Enzyme NA NA "Cluster 17: Intestine - Digestion" "Cluster 34: Non-specific - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 70: Intestinal goblet cells - Mucin production" "HPA039805: " "unprognostic (1.86e-3)" "unprognostic (1.35e-1)" "unprognostic (9.93e-2)" "potential prognostic unfavorable (2.20e-4)" "unprognostic (8.83e-3)" "unprognostic (2.81e-1)" "unprognostic (1.45e-1)" "unprognostic (5.46e-2)" "potential prognostic unfavorable (2.13e-4)" "unprognostic (1.24e-1)" B3GNT7 beta3GnT7 ENSG00000156966 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7" Q8NFL0 2 231395710-231401164 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 66.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 81.7;Cholangiocytes: 74.4;Colonocytes: 393.6;Enteric stem cells: 194.8;Enteric transient amplifying cells: 185.7;Enterocytes: 82.2;Extravillous trophoblasts: 101.7;Foveolar cells: 116.9;Goblet cells: 88.9;Oligodendrocyte progenitor cells: 82.0" "Group enriched" "Detected in some" 14 "committed oligodendrocyte precursor: 60.9;oligodendrocyte precursor cell: 84.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 32.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA013881, HPA035625, HPA035626" Enhanced Approved "Golgi apparatus,Mitotic spindle,Cytosol" Yes NA 940000 "Cluster 14: Non-specific - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 69: Skin cancer - ECM organization" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 1 "Golgi apparatus" "Mitotic spindle, Cytosol" "HPA013881: , HPA035625: , HPA035626: " "unprognostic (6.14e-2)" "unprognostic (2.63e-2)" "unprognostic (1.28e-1)" "unprognostic (2.44e-1)" "potential prognostic favorable (6.70e-4)" "unprognostic (1.75e-1)" "unprognostic (4.72e-2)" "potential prognostic unfavorable (1.77e-4)" "unprognostic (1.79e-1)" "unprognostic (4.37e-2)" "unprognostic (1.12e-2)" "unprognostic (1.76e-1)" "unprognostic (6.43e-3)" "unprognostic (1.11e-1)" "unprognostic (2.55e-2)" "unprognostic (2.83e-2)" "unprognostic (4.57e-3)" "potential prognostic unfavorable (9.69e-5)" "unprognostic (3.04e-2)" "unprognostic (5.38e-2)" "unprognostic (1.77e-2)" "unprognostic (7.60e-3)" "unprognostic (1.39e-1)" "unprognostic (1.79e-1)" "unprognostic (3.02e-2)" "unprognostic (2.03e-2)" "unprognostic (1.32e-1)" "unprognostic (7.68e-2)" "unprognostic (1.18e-1)" "unprognostic (1.41e-2)" "unprognostic (1.98e-1)" B3GNT8 "B3GALT7, beta3Gn-T8, BGALT15" ENSG00000177191 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8" Q7Z7M8 19 41425359-41428730 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 11.8;intestine: 18.6" "Cell type enriched" "Detected in many" 6 "Esophageal apical cells: 659.0" "Cell type enhanced" "Detected in some" "fibroblast: 2.5;leukocyte: 1.2;pericyte: 1.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 117.8;eosinophil: 146.9;neutrophil: 198.3" "Lineage enriched" "Detected in many" 6 "granulocytes: 198.3" "Cancer enhanced" "Detected in many" "colorectal cancer: 5.3;Leukemia: 5.2" "Spleen - Neutrophils_2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA043669 Enhanced "Intracellular and membrane" Enzyme NA NA 9100000 "Cluster 21: Neutrophils - Unknown function" "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 6: Non-specific - Immune response" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 84: Apical squamous epithelium - Cornification" 1 "HPA043669: " "unprognostic (8.89e-3)" "unprognostic (1.37e-1)" "unprognostic (2.08e-1)" "unprognostic (3.43e-1)" "unprognostic (1.90e-2)" "unprognostic (8.47e-2)" "unprognostic (2.55e-2)" "unprognostic (3.97e-3)" "potential prognostic unfavorable (1.92e-4)" "unprognostic (5.59e-2)" "unprognostic (3.70e-2)" "unprognostic (2.32e-1)" "unprognostic (3.26e-3)" "unprognostic (1.82e-1)" "unprognostic (6.06e-2)" "unprognostic (2.94e-1)" "unprognostic (1.99e-3)" "unprognostic (7.19e-3)" "potential prognostic favorable (5.37e-6)" "unprognostic (2.55e-3)" "unprognostic (5.13e-3)" "unprognostic (3.51e-2)" "unprognostic (3.79e-3)" "unprognostic (1.33e-1)" "unprognostic (1.76e-1)" "unprognostic (6.18e-2)" "unprognostic (8.42e-2)" "unprognostic (1.09e-1)" B3GNT9 MGC4655 ENSG00000237172 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9" Q6UX72 16 67148104-67150998 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast lactating cells: 17.3;Peritubular myoid cells: 15.9" "Cell type enhanced" "Detected in many" "ependymal cell: 9.6;fibroblast: 8.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Adrenal gland - Fibroblasts, Breast - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblasts_2, Minor Salivary Gland - Minor salivary glandular cells, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052743, HPA062734" Approved Approved "Nucleoli fibrillar center,Golgi apparatus" "Intracellular and membrane" Enzyme NA NA "Cluster 75: Ovary - Mixed function" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 1 "Golgi apparatus" "Nucleoli fibrillar center" "HPA052743: , HPA062734: " "unprognostic (2.56e-2)" "unprognostic (7.38e-2)" "unprognostic (1.79e-1)" "unprognostic (5.91e-2)" "unprognostic (1.91e-2)" "unprognostic (3.38e-2)" "unprognostic (3.76e-2)" "unprognostic (1.07e-2)" "unprognostic (1.06e-1)" "unprognostic (2.00e-1)" "unprognostic (2.94e-3)" "unprognostic (2.05e-1)" "unprognostic (5.63e-2)" "unprognostic (5.68e-3)" "unprognostic (1.46e-1)" "unprognostic (2.55e-2)" "unprognostic (1.32e-1)" "unprognostic (4.46e-2)" "unprognostic (4.54e-2)" "unprognostic (3.05e-1)" "unprognostic (1.26e-1)" "unprognostic (5.43e-2)" "unprognostic (4.40e-2)" "unprognostic (9.71e-3)" "unprognostic (2.46e-2)" "unprognostic (1.22e-1)" "unprognostic (5.77e-2)" "unprognostic (6.88e-3)" "unprognostic (2.08e-1)" "unprognostic (2.44e-2)" "unprognostic (2.84e-1)" B3GNTL1 B3GNT8 ENSG00000175711 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase like 1" Q67FW5 17 82942149-83051809 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 5.8" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 30.4;Epididymal principal cells: 27.4;Late spermatids: 28.3;Neutrophils: 42.4;Oocytes: 27.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 6.2" "Lineage enriched" "Detected in many" 4 "granulocytes: 6.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023585, HPA024547" Supported Approved "Nucleoli,Nucleoli fibrillar center,Vesicles" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 15: Bone marrow - Innate immune response" "Cluster 23: Choroid plexus - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Neutrophils - Innate immune cellular maintenance" "Nucleoli, Nucleoli fibrillar center" Vesicles "HPA023585: , HPA024547: " "unprognostic (1.49e-1)" "unprognostic (7.61e-3)" "unprognostic (2.02e-2)" "unprognostic (5.51e-2)" "unprognostic (1.62e-1)" "unprognostic (3.21e-1)" "unprognostic (1.00e-1)" "unprognostic (1.64e-2)" "unprognostic (1.04e-2)" "unprognostic (2.36e-1)" "validated prognostic unfavorable (2.78e-7)" "validated prognostic unfavorable (3.63e-4)" "unprognostic (1.08e-1)" "potential prognostic unfavorable (1.13e-7)" "unprognostic (1.39e-3)" "unprognostic (5.34e-2)" "unprognostic (1.46e-1)" "unprognostic (2.84e-1)" "unprognostic (3.11e-2)" "unprognostic (1.53e-1)" "unprognostic (1.37e-2)" "unprognostic (2.62e-1)" "unprognostic (1.41e-1)" "unprognostic (7.00e-2)" "unprognostic (2.54e-1)" "unprognostic (1.64e-1)" "unprognostic (1.53e-1)" "unprognostic (2.37e-2)" "unprognostic (3.51e-1)" "unprognostic (7.38e-2)" "unprognostic (2.06e-1)" B4GALNT1 "beta1-4GalNAc-T, GALGT, SPG26" ENSG00000135454 "Beta-1,4-N-acetyl-galactosaminyltransferase 1" Q00973 12 57623409-57633239 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Sphingolipid metabolism" "Glycosyltransferase, Transferase" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 83.9" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 39.4;Brain inhibitory neurons: 33.2;Epicardial cells: 11.4;Innate lymphoid cells: 6.9;Other brain neurons: 32.4;Pericytes: 7.7;Retinal amacrine cells: 15.5;Retinal ganglion cells: 7.7;Schwann cells: 20.8;Vascular smooth muscle cells: 12.7" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in many" 4 "Glioblastoma Multiforme (TCGA): 49.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 96.0" "Adipose subcutaneous - Smooth muscle cells, Colon - Enteric glia cells, Kidney - Fibroblasts, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008968 Enhanced "Intracellular and membrane" Enzyme NA NA 37000 "Cluster 27: Cerebellum - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 38: Non-specific - Transcription" "Cluster 35: Neurons - Synaptic function & neurogenesis" 3 "HPA008968: " "unprognostic (6.09e-3)" "unprognostic (1.68e-1)" "unprognostic (4.26e-2)" "unprognostic (5.44e-2)" "unprognostic (1.18e-1)" "unprognostic (1.49e-1)" "potential prognostic favorable (2.48e-4)" "unprognostic (1.57e-3)" "unprognostic (3.96e-2)" "unprognostic (3.65e-3)" "unprognostic (9.93e-2)" "potential prognostic unfavorable (1.37e-7)" "potential prognostic unfavorable (3.54e-4)" "unprognostic (3.60e-3)" "potential prognostic unfavorable (6.17e-5)" "unprognostic (2.79e-3)" "unprognostic (1.16e-1)" "unprognostic (6.19e-3)" "unprognostic (1.95e-1)" "unprognostic (9.98e-2)" "unprognostic (6.09e-2)" "unprognostic (2.68e-1)" "unprognostic (2.43e-2)" "unprognostic (1.84e-1)" "unprognostic (2.14e-1)" "unprognostic (7.44e-3)" "unprognostic (5.93e-2)" "potential prognostic unfavorable (8.39e-4)" B4GALNT2 "Cad, GALGT2, Sda" ENSG00000167080 "Beta-1,4-N-acetyl-galactosaminyltransferase 2" Q8NHY0 17 49132460-49176840 "Disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 31.4" "Cell type enhanced" "Detected in some" "Colonocytes: 38.8;Enteric transient amplifying cells: 27.3;Enterocytes: 50.0;Gastric chief cells: 32.8;Goblet cells: 72.5;Mucous neck cells: 19.4;Renal collecting duct intercalated cells: 44.4;Renal collecting duct principal cells: 50.5;Salivary ionocytes: 109.7" "Cell type enhanced" "Detected in some" "fibroblast: 1.8" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 15.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells (progenitors), Colon - Colon enterocytes, Skin - Outer root sheath cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA015721 Approved NA NA "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 70: Intestinal goblet cells - Mucin production" 2 "HPA015721: " "unprognostic (3.77e-1)" "unprognostic (4.73e-2)" "unprognostic (2.38e-1)" "unprognostic (3.29e-2)" "unprognostic (9.34e-2)" "unprognostic (1.51e-1)" "unprognostic (9.00e-2)" "unprognostic (1.22e-2)" "unprognostic (6.48e-3)" "unprognostic (3.29e-1)" "unprognostic (8.38e-2)" "potential prognostic favorable (9.81e-4)" "unprognostic (1.47e-1)" "potential prognostic unfavorable (8.85e-5)" "unprognostic (1.86e-2)" "unprognostic (1.59e-1)" "unprognostic (2.20e-1)" "unprognostic (9.40e-2)" "unprognostic (5.74e-2)" "unprognostic (5.05e-2)" "unprognostic (1.09e-1)" "unprognostic (1.21e-1)" "unprognostic (1.61e-2)" "unprognostic (1.25e-1)" "unprognostic (5.06e-3)" "unprognostic (1.81e-3)" B4GALNT3 "B4GalNac-T3, FLJ16224, FLJ40362" ENSG00000139044 "Beta-1,4-N-acetyl-galactosaminyltransferase 3" Q6L9W6 12 459939-563509 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 22.4;stomach 1: 57.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 348.1;Colonocytes: 347.7;Endometrial glandular cells: 546.2;Foveolar cells: 977.2;Ocular epithelial cells: 562.0;Suprabasal keratinocytes: 493.8;Thyrotrophs: 349.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA011404 Enhanced Supported "Golgi apparatus,Vesicles" NA NA "Cluster 17: Intestine - Digestion" "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 1 "Golgi apparatus" Vesicles "HPA011404: " "unprognostic (7.42e-3)" "unprognostic (1.95e-1)" "unprognostic (6.25e-2)" "unprognostic (2.06e-1)" "unprognostic (1.22e-2)" "unprognostic (1.47e-1)" "unprognostic (1.34e-1)" "unprognostic (1.21e-1)" "unprognostic (3.47e-1)" "unprognostic (1.04e-1)" "unprognostic (9.39e-2)" "unprognostic (8.52e-2)" "unprognostic (1.67e-1)" "unprognostic (7.90e-3)" "potential prognostic unfavorable (6.55e-4)" "unprognostic (2.01e-1)" "unprognostic (1.05e-1)" "unprognostic (4.97e-1)" "unprognostic (3.29e-2)" "unprognostic (9.76e-2)" "unprognostic (9.87e-2)" "unprognostic (5.47e-2)" "unprognostic (1.02e-2)" "unprognostic (2.91e-1)" "unprognostic (3.08e-1)" "unprognostic (5.52e-2)" "unprognostic (3.03e-1)" "unprognostic (1.72e-1)" "unprognostic (2.28e-1)" B4GALNT4 "FLJ25045, NGalNAc-T1" ENSG00000182272 "Beta-1,4-N-acetyl-galactosaminyltransferase 4" Q76KP1 11 369499-382117 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 63.4;ovary: 23.8" "Cell type enhanced" "Detected in many" "Astrocytes: 180.2;Bergmann glia: 55.9;Brain excitatory neurons: 38.6;Brain inhibitory neurons: 45.3;Müller glia: 43.9;Oligodendrocyte progenitor cells: 38.6;Oligodendrocytes: 36.6;Other brain neurons: 40.0;Tuft cells: 196.0" "Cell type enhanced" "Detected in all" "astrocyte: 208.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Pituitary gland - Corticotropes, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043276, HPA053126" Uncertain Uncertain Nucleoplasm,Vesicles,Cytosol NA No "Cluster 27: Cerebellum - Synaptic function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 28: Astrocytes - Homeostasis & neuron support" "Nucleoplasm, Cytosol" Vesicles "HPA043276: , HPA053126: " "unprognostic (2.55e-2)" "unprognostic (2.71e-1)" "unprognostic (4.97e-2)" "unprognostic (1.55e-1)" "unprognostic (1.82e-1)" "unprognostic (4.83e-2)" "unprognostic (7.03e-2)" "unprognostic (3.25e-2)" "unprognostic (2.32e-1)" "potential prognostic unfavorable (2.77e-4)" "unprognostic (8.95e-2)" "unprognostic (5.07e-2)" "unprognostic (1.48e-1)" "unprognostic (2.91e-1)" "potential prognostic favorable (5.80e-4)" "unprognostic (2.14e-1)" "unprognostic (8.90e-3)" "unprognostic (1.98e-3)" "potential prognostic unfavorable (3.34e-4)" "unprognostic (5.47e-3)" "unprognostic (9.63e-2)" "unprognostic (1.94e-2)" "unprognostic (1.09e-1)" "unprognostic (1.58e-1)" "unprognostic (1.67e-1)" "unprognostic (7.03e-2)" B4GALT1 "beta4Gal-T1, GGTB2" ENSG00000086062 "Beta-1,4-galactosyltransferase 1" P15291 9 33104082-33167356 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Breast lactating cells: 1650.3;Neutrophils: 1062.1" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 195.8;endothelial cell: 198.7;leukocyte: 137.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 215.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010806, HPA010807" Enhanced Enhanced "Golgi apparatus" "Intracellular and membrane" Enzyme NA NA 22000000 "Cluster 30: Non-specific - DNA binding" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 7: Liver cancer - Metabolism" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 2 "Golgi apparatus" "HPA010806: , HPA010807: " "unprognostic (2.40e-2)" "unprognostic (7.50e-2)" "unprognostic (1.57e-1)" "unprognostic (3.79e-3)" "unprognostic (3.76e-2)" "potential prognostic unfavorable (7.32e-4)" "unprognostic (4.50e-3)" "unprognostic (1.32e-2)" "unprognostic (1.72e-1)" "unprognostic (2.04e-2)" "unprognostic (4.50e-3)" "unprognostic (1.89e-1)" "unprognostic (1.96e-1)" "unprognostic (3.97e-2)" "unprognostic (1.14e-1)" "potential prognostic unfavorable (1.01e-4)" "unprognostic (1.29e-2)" "unprognostic (8.04e-2)" "unprognostic (1.25e-1)" "unprognostic (3.43e-1)" "unprognostic (6.38e-2)" "potential prognostic unfavorable (6.63e-4)" "unprognostic (1.93e-2)" "unprognostic (3.88e-1)" "unprognostic (2.24e-1)" "unprognostic (1.06e-1)" "unprognostic (2.19e-1)" "unprognostic (5.10e-2)" "unprognostic (3.99e-2)" "unprognostic (4.30e-2)" "unprognostic (6.20e-2)" B4GALT2 beta4Gal-T2 ENSG00000117411 "Beta-1,4-galactosyltransferase 2" O60909 1 43978943-43991170 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Stomach - Fibroblasts, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007620, HPA047739" Supported Supported "Golgi apparatus,Vesicles" NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 51: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" "Golgi apparatus, Vesicles" "HPA007620: , HPA047739: " "unprognostic (2.48e-1)" "unprognostic (1.76e-2)" "unprognostic (3.18e-1)" "unprognostic (1.03e-3)" "unprognostic (2.09e-1)" "unprognostic (3.72e-1)" "unprognostic (1.30e-1)" "unprognostic (1.93e-1)" "unprognostic (2.07e-1)" "unprognostic (2.43e-2)" "unprognostic (6.41e-3)" "unprognostic (1.11e-2)" "unprognostic (1.61e-1)" "validated prognostic unfavorable (8.42e-9)" "validated prognostic unfavorable (7.07e-4)" "unprognostic (4.94e-2)" "unprognostic (1.98e-3)" "unprognostic (1.17e-1)" "unprognostic (2.48e-1)" "unprognostic (1.69e-1)" "unprognostic (1.09e-1)" "unprognostic (6.37e-3)" "unprognostic (1.72e-2)" "unprognostic (1.32e-1)" "unprognostic (5.22e-2)" "unprognostic (2.89e-1)" "unprognostic (1.73e-1)" "unprognostic (1.07e-1)" "unprognostic (9.71e-2)" "unprognostic (7.67e-3)" "unprognostic (1.13e-1)" B4GALT3 beta4Gal-T3 ENSG00000158850 "Beta-1,4-galactosyltransferase 3" O60512 1 161171310-161177968 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 91.8;Extravillous trophoblasts: 119.5;Migrating cytotrophoblasts: 67.7;Plasma cells: 76.1;Syncytiotrophoblasts: 144.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in all" 4 "Myeloma: 192.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010793 Approved Supported "Golgi apparatus,Cytosol" NA NA 14000 "Cluster 13: Non-specific - Mitochondria" "Cluster 70: Non-specific - Protein processing" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 67: Plasma cells - Plasma cell differentiation" 36 "Golgi apparatus" Cytosol "HPA010793: " "unprognostic (1.54e-1)" "unprognostic (2.68e-3)" "unprognostic (1.96e-1)" "unprognostic (1.17e-3)" "unprognostic (1.41e-1)" "unprognostic (2.02e-2)" "unprognostic (6.97e-2)" "unprognostic (1.87e-2)" "unprognostic (3.21e-3)" "unprognostic (1.33e-1)" "unprognostic (2.78e-2)" "unprognostic (1.53e-1)" "unprognostic (6.08e-3)" "potential prognostic unfavorable (7.97e-5)" "unprognostic (1.99e-3)" "unprognostic (3.33e-2)" "unprognostic (3.56e-3)" "unprognostic (9.09e-2)" "unprognostic (9.78e-2)" "unprognostic (2.40e-2)" "unprognostic (2.33e-1)" "unprognostic (2.38e-1)" "unprognostic (2.07e-1)" "unprognostic (4.06e-2)" "unprognostic (2.79e-2)" "unprognostic (1.98e-3)" "unprognostic (2.83e-1)" "unprognostic (5.12e-1)" "unprognostic (2.92e-1)" "unprognostic (5.12e-2)" "unprognostic (3.30e-1)" B4GALT4 beta4Gal-T4 ENSG00000121578 "Beta-1,4-galactosyltransferase 4" O60513 3 119211732-119240946 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 127.4;Extravillous trophoblasts: 188.7;Urothelial cells: 137.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046819, HPA063546" Approved Supported "Golgi apparatus" "Intracellular and membrane" Enzyme NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 22: Epididymis - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 51: Secretory epithelial cells - Mixed function" 16 "Golgi apparatus" "HPA046819: , HPA063546: " "unprognostic (6.80e-2)" "unprognostic (5.76e-3)" "unprognostic (1.02e-1)" "unprognostic (2.34e-1)" "unprognostic (5.67e-2)" "unprognostic (1.41e-1)" "unprognostic (2.04e-2)" "unprognostic (5.00e-3)" "unprognostic (8.41e-2)" "potential prognostic unfavorable (5.02e-4)" "unprognostic (3.35e-2)" "unprognostic (1.56e-1)" "unprognostic (5.60e-3)" "potential prognostic unfavorable (6.81e-5)" "unprognostic (1.21e-3)" "potential prognostic unfavorable (2.30e-4)" "unprognostic (4.14e-2)" "unprognostic (2.48e-2)" "unprognostic (2.91e-2)" "unprognostic (2.32e-1)" "unprognostic (1.20e-2)" "unprognostic (4.77e-3)" "unprognostic (4.87e-2)" "unprognostic (5.73e-2)" "unprognostic (2.36e-1)" "unprognostic (1.09e-2)" "unprognostic (1.23e-1)" "unprognostic (4.54e-2)" "unprognostic (1.63e-1)" "unprognostic (1.20e-1)" "unprognostic (5.54e-3)" B4GALT5 beta4GalT-V ENSG00000158470 "Beta-1,4-galactosyltransferase 5" O43286 20 49632945-49713878 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Sphingolipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Mast cells: 673.6;Neutrophil progenitors: 1670.6;Neutrophils: 1511.7;Ocular epithelial cells: 681.8;Urothelial cells: 733.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 6.6" "Lineage enriched" "Detected in many" 4 "granulocytes: 6.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077777 Approved Vesicles NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 1: Neurons - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 15 Vesicles "HPA077777: " "unprognostic (1.69e-2)" "unprognostic (8.62e-2)" "unprognostic (9.39e-2)" "unprognostic (3.05e-2)" "unprognostic (1.03e-1)" "unprognostic (3.08e-2)" "unprognostic (2.81e-1)" "unprognostic (1.21e-1)" "unprognostic (8.84e-2)" "unprognostic (3.94e-2)" "unprognostic (2.54e-3)" "unprognostic (1.09e-1)" "unprognostic (5.26e-2)" "potential prognostic unfavorable (1.25e-5)" "unprognostic (3.80e-3)" "unprognostic (9.96e-2)" "unprognostic (9.22e-3)" "unprognostic (1.83e-1)" "unprognostic (3.79e-1)" "unprognostic (1.53e-2)" "unprognostic (8.86e-3)" "potential prognostic unfavorable (1.30e-4)" "unprognostic (3.41e-3)" "unprognostic (1.67e-1)" "unprognostic (7.61e-3)" "unprognostic (2.34e-2)" "unprognostic (2.53e-1)" "unprognostic (3.59e-2)" "unprognostic (3.24e-1)" "unprognostic (1.01e-1)" "unprognostic (1.83e-1)" B4GALT6 beta4GalT-VI ENSG00000118276 "Beta-1,4-galactosyltransferase 6" Q9UBX8 18 31622246-31685836 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Sphingolipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 24.7" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 151.5;Brain inhibitory neurons: 129.7;Cone photoreceptor cells: 128.3;Lactotrophs: 136.2;Retinal amacrine cells: 152.0;Retinal bipolar cells: 560.2;Retinal ganglion cells: 154.5;Somatotrophs: 125.9;Thymocytes: 129.6;Thyrotrophs: 188.4" "Cell type enhanced" "Detected in all" "midbrain-derived inhibitory: 503.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "NK-cell: 1.4" "Lineage enriched" "Detected in single" 5 "NK-cells: 1.4" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Prostate - Fibroblasts, Testis - Spermatogonia, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020701, HPA058284" Approved NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 1 "CAB020701: , HPA058284: " "unprognostic (3.60e-2)" "unprognostic (2.36e-1)" "unprognostic (6.79e-2)" "unprognostic (4.52e-2)" "unprognostic (2.65e-3)" "unprognostic (5.87e-2)" "unprognostic (2.84e-1)" "unprognostic (1.89e-2)" "unprognostic (2.06e-1)" "potential prognostic unfavorable (8.11e-4)" "potential prognostic favorable (2.45e-6)" "unprognostic (7.77e-3)" "unprognostic (8.70e-2)" "unprognostic (1.49e-2)" "potential prognostic unfavorable (5.04e-4)" "unprognostic (2.41e-1)" "unprognostic (2.00e-1)" "unprognostic (3.69e-2)" "unprognostic (1.85e-1)" "unprognostic (1.05e-1)" "unprognostic (1.15e-1)" "unprognostic (1.10e-1)" "unprognostic (4.78e-1)" "unprognostic (2.70e-2)" "unprognostic (6.77e-2)" "unprognostic (1.80e-1)" "unprognostic (3.16e-1)" "unprognostic (2.25e-1)" "unprognostic (2.20e-1)" "unprognostic (1.07e-2)" B4GALT7 "beta4Gal-T7, XGALT-1" ENSG00000027847 "Beta-1,4-galactosyltransferase 7" Q9UBV7 5 177600132-177610330 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Disease variant, Dwarfism, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 186.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042330 Supported NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 8 "HPA042330: " "unprognostic (1.48e-1)" "unprognostic (8.42e-2)" "unprognostic (1.61e-1)" "unprognostic (1.02e-1)" "unprognostic (2.50e-1)" "unprognostic (1.48e-2)" "potential prognostic unfavorable (7.67e-4)" "unprognostic (1.78e-1)" "unprognostic (8.48e-2)" "unprognostic (2.12e-1)" "unprognostic (3.81e-3)" "potential prognostic unfavorable (4.95e-4)" "unprognostic (2.85e-1)" "potential prognostic unfavorable (2.89e-5)" "unprognostic (3.12e-3)" "unprognostic (6.93e-2)" "unprognostic (7.01e-2)" "unprognostic (3.48e-1)" "unprognostic (4.11e-1)" "unprognostic (7.59e-2)" "unprognostic (7.68e-2)" "unprognostic (2.05e-2)" "unprognostic (2.80e-1)" "unprognostic (9.01e-2)" "unprognostic (2.86e-2)" "unprognostic (1.42e-3)" "unprognostic (1.38e-1)" "unprognostic (5.66e-2)" "unprognostic (1.48e-1)" "unprognostic (2.74e-2)" "unprognostic (1.09e-1)" B4GAT1 "B3GN-T1, B3GNT1, B3GNT6, BETA3GNTI, iGAT, IGnT" ENSG00000174684 "Beta-1,4-glucuronyltransferase 1" O43505 11 66345374-66347629 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Lissencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 207.3" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 53.6;Cytotrophoblasts: 66.1;Granulosa cells: 56.0;Müller glia: 63.8;Other brain neurons: 121.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015484 Uncertain "Intracellular and membrane" Enzyme NA NA 25000000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 18: Liver cancer - Metabolism" "Cluster 98: Neurons - Neurotransmission & signaling" 45 "HPA015484: " "unprognostic (1.01e-2)" "unprognostic (8.35e-2)" "unprognostic (1.31e-1)" "unprognostic (1.77e-2)" "unprognostic (3.54e-1)" "unprognostic (9.61e-2)" "unprognostic (8.87e-2)" "unprognostic (6.23e-2)" "potential prognostic unfavorable (4.21e-5)" "potential prognostic favorable (1.06e-6)" "unprognostic (1.31e-2)" "unprognostic (8.32e-2)" "unprognostic (2.71e-2)" "unprognostic (2.48e-1)" "unprognostic (3.03e-2)" "unprognostic (2.41e-1)" "unprognostic (3.67e-2)" "unprognostic (4.28e-3)" "unprognostic (3.49e-2)" "potential prognostic favorable (4.35e-4)" "unprognostic (2.31e-3)" "unprognostic (4.74e-2)" "unprognostic (1.07e-1)" "unprognostic (1.05e-1)" "unprognostic (1.47e-1)" "unprognostic (1.16e-2)" "unprognostic (1.93e-1)" "unprognostic (1.08e-1)" "unprognostic (3.13e-1)" B9D1 "B9, EPPB9, MKS9, MKSR-1" ENSG00000108641 "B9 domain containing 1" Q9UPM9 17 19334308-19378193 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome, Meckel syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 212.9;Epicardial cells: 127.4;Epididymal efferent duct ciliated cells: 177.1;Epididymal principal cells: 132.8;Fallopian tube ciliated cells: 235.6;Late primary spermatocytes: 334.1;Late spermatids: 223.8;Respiratory ciliated cells: 256.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022957 Approved Uncertain "Nucleoplasm,Vesicles,Basal body,Cytosol,Acrosome,Equatorial segment,Mid piece,Principal piece,End piece" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 27: Breast cancer - Unknown function" "Cluster 107: Ciliated cells - Cilia assembly & function" 12 "Nucleoplasm, Acrosome, Equatorial segment, Mid piece" "Vesicles, Basal body, Cytosol, Principal piece, End piece" "HPA022957: " "unprognostic (8.06e-3)" "unprognostic (2.45e-1)" "unprognostic (5.70e-1)" "unprognostic (6.04e-3)" "unprognostic (2.35e-2)" "unprognostic (3.65e-1)" "unprognostic (8.88e-3)" "unprognostic (1.15e-1)" "unprognostic (2.23e-2)" "unprognostic (3.68e-2)" "unprognostic (2.01e-3)" "unprognostic (2.66e-1)" "potential prognostic favorable (2.13e-8)" "unprognostic (1.93e-3)" "unprognostic (7.68e-3)" "unprognostic (2.55e-1)" "unprognostic (2.72e-2)" "unprognostic (3.11e-1)" "unprognostic (1.03e-1)" "unprognostic (2.18e-1)" "unprognostic (5.95e-2)" "unprognostic (1.13e-2)" "unprognostic (7.75e-2)" "unprognostic (2.16e-1)" "unprognostic (3.65e-1)" "unprognostic (1.87e-1)" "unprognostic (2.64e-1)" "unprognostic (7.88e-2)" "unprognostic (9.89e-2)" "unprognostic (7.04e-2)" "unprognostic (6.16e-2)" B9D2 "MGC4093, MKS10, MKSR-2" ENSG00000123810 "B9 domain containing 2" Q9BPU9 19 41354417-41364165 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome, Meckel syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 64.0;Epididymal efferent duct ciliated cells: 52.5;Fallopian tube ciliated cells: 79.9;Late spermatids: 56.1;Respiratory ciliated cells: 95.9" "Cell type enhanced" "Detected in many" "ependymal cell: 9.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 128.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042229, HPA042618" Enhanced Uncertain "Nucleoli,Golgi apparatus,Vesicles,Centrosome,Basal body" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 4: Non-specific - Transcription" "Cluster 107: Ciliated cells - Cilia assembly & function" 27 "Nucleoli, Golgi apparatus" "Vesicles, Centrosome, Basal body" "HPA042229: , HPA042618: " "unprognostic (2.87e-1)" "unprognostic (1.96e-1)" "unprognostic (1.52e-2)" "potential prognostic favorable (1.95e-4)" "unprognostic (1.21e-1)" "unprognostic (5.46e-3)" "unprognostic (7.34e-2)" "unprognostic (1.08e-1)" "unprognostic (3.24e-3)" "unprognostic (4.29e-2)" "potential prognostic favorable (1.16e-5)" "unprognostic (1.45e-1)" "unprognostic (6.39e-2)" "unprognostic (5.47e-3)" "potential prognostic favorable (8.08e-4)" "unprognostic (2.55e-1)" "unprognostic (1.93e-1)" "unprognostic (2.18e-1)" "unprognostic (2.60e-1)" "unprognostic (1.75e-1)" "unprognostic (1.61e-2)" "unprognostic (2.78e-2)" "unprognostic (3.45e-2)" "unprognostic (3.33e-1)" "unprognostic (1.16e-1)" "unprognostic (4.24e-2)" "unprognostic (5.81e-3)" "unprognostic (1.08e-1)" "unprognostic (3.49e-1)" "unprognostic (1.44e-1)" "unprognostic (1.42e-1)" BAALC ENSG00000164929 "BAALC binder of MAP3K1 and KLF4" Q8WXS3 8 103140713-103230305 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "brain: 274.0" "Cell type enhanced" "Detected in many" "Astrocytes: 293.3;Bergmann glia: 407.4;Endometrial luminal cells: 93.8;Hematopoietic stem cells: 100.4;Lactotrophs: 117.3;Müller glia: 130.0;Oligodendrocyte progenitor cells: 234.4;Pituitary stem cells: 118.8;Somatotrophs: 86.0;Thymocytes: 227.0;Thyrotrophs: 92.6" "Cell type enhanced" "Detected in all" "Bergmann glia: 413.3" "Cancer enriched" "Detected in many" 8 "Glioblastoma Multiforme (TCGA): 339.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 28 "NK-cell: 3.7" "Lineage enriched" "Detected in single" 28 "NK-cells: 3.7" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Thyroid gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027132, HPA068307" Approved Supported Nucleoplasm,Cytosol No NA "Cluster 14: Non-specific - Unknown function" "Cluster 78: Brain - Neuronal signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 28: Astrocytes - Homeostasis & neuron support" 2 Cytosol Nucleoplasm "HPA027132: , HPA068307: " "unprognostic (2.68e-1)" "unprognostic (1.54e-1)" "unprognostic (2.28e-1)" "unprognostic (3.88e-3)" "unprognostic (3.40e-1)" "unprognostic (2.39e-2)" "unprognostic (1.50e-1)" "unprognostic (2.08e-1)" "unprognostic (2.38e-1)" "unprognostic (3.11e-2)" "unprognostic (1.89e-1)" "unprognostic (5.81e-1)" "unprognostic (1.10e-1)" "unprognostic (2.19e-2)" "unprognostic (8.23e-2)" "unprognostic (5.06e-2)" "unprognostic (2.56e-1)" "unprognostic (1.55e-1)" "unprognostic (1.68e-2)" "unprognostic (1.88e-2)" "unprognostic (7.21e-3)" "potential prognostic unfavorable (5.44e-4)" "unprognostic (1.02e-2)" "unprognostic (1.02e-1)" "potential prognostic unfavorable (1.10e-4)" "unprognostic (1.83e-1)" "unprognostic (2.90e-1)" "unprognostic (8.74e-2)" BAAT BAT ENSG00000136881 "Bile acid-CoA:amino acid N-acyltransferase" Q14032 9 101354182-101385400 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Hydrolase, Serine esterase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 41 "liver: 674.5" "Cell type enriched" "Detected in some" 13 "Hepatocytes: 674.5" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in some" 29 "Liver Hepatocellular Carcinoma (TCGA): 223.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 13.2" "Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA021251, HPA021330" Enhanced Supported Vesicles,Cytosol NA NA 320000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 7: Liver cancer - Metabolism" "Cluster 93: Hepatocytes - Bile production & excretion" 9 Vesicles Cytosol "HPA021251: , HPA021330: " "unprognostic (9.91e-2)" "unprognostic (2.09e-1)" "unprognostic (1.81e-1)" "unprognostic (1.10e-3)" "unprognostic (9.27e-3)" "potential prognostic favorable (4.67e-4)" "unprognostic (1.26e-1)" "unprognostic (2.27e-1)" "unprognostic (5.05e-2)" "unprognostic (1.90e-1)" "unprognostic (2.98e-1)" "unprognostic (3.48e-1)" BABAM1 "C19orf62, FLJ20571, HSPC142, MERIT40, NBA1" ENSG00000105393 "BRISC and BRCA1 A complex member 1" Q9NWV8 19 17267376-17281249 "Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Mitosis, Ubl conjugation pathway" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 14.9;Bergmann glia: 20.0;Brain excitatory neurons: 27.9;Brain inhibitory neurons: 23.8;Choroid plexus epithelial cells: 10.5;Microglia: 20.2;Oligodendrocyte progenitor cells: 20.2;Oligodendrocytes: 22.2;Other brain neurons: 28.0;Parietal cells: 10.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054386, HPA068786, HPA077609" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" No No "Cluster 29: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 23: Non-specific - Transcription" "Cluster 98: Neurons - Neurotransmission & signaling" 21 "Nuclear bodies" "Nucleoplasm, Cytosol" "HPA054386: , HPA068786: , HPA077609: " "unprognostic (4.91e-2)" "unprognostic (1.47e-1)" "unprognostic (2.28e-1)" "unprognostic (1.44e-1)" "unprognostic (7.90e-2)" "unprognostic (5.23e-2)" "unprognostic (7.64e-2)" "unprognostic (2.12e-1)" "unprognostic (2.33e-2)" "unprognostic (1.74e-3)" "unprognostic (1.39e-1)" "unprognostic (2.53e-2)" "unprognostic (3.04e-3)" "unprognostic (1.71e-3)" "unprognostic (2.09e-1)" "unprognostic (2.28e-1)" "unprognostic (1.69e-2)" "unprognostic (1.79e-2)" "unprognostic (2.25e-1)" "unprognostic (1.29e-1)" "unprognostic (1.40e-1)" "unprognostic (1.96e-1)" "unprognostic (6.39e-2)" "unprognostic (4.79e-2)" "unprognostic (1.74e-3)" "potential prognostic unfavorable (4.93e-4)" "unprognostic (1.50e-1)" "unprognostic (2.87e-1)" "unprognostic (3.22e-2)" "unprognostic (1.19e-1)" BABAM2 "BRCC4, BRCC45, BRE" ENSG00000158019 "BRISC and BRCA1 A complex member 2" Q9NXR7 2 27889941-28338901 "Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, DNA damage, DNA repair, Mitosis, Ubl conjugation pathway" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "adrenal gland: 356.9" "Cell type enhanced" "Detected in all" "Adrenal cortex cells: 2215.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017926, HPA048867" Enhanced Supported Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 18: Adrenal cortex cells - Steroidogensis" 31 Cytosol "HPA017926: , HPA048867: " "unprognostic (4.37e-1)" "unprognostic (3.42e-2)" "unprognostic (2.24e-3)" "unprognostic (1.04e-2)" "unprognostic (7.08e-2)" "unprognostic (1.05e-1)" "unprognostic (2.33e-2)" "unprognostic (1.70e-2)" "unprognostic (2.59e-1)" "unprognostic (2.39e-3)" "unprognostic (9.50e-2)" "unprognostic (5.57e-2)" "potential prognostic unfavorable (1.80e-4)" "unprognostic (7.39e-2)" "unprognostic (2.06e-1)" "unprognostic (2.23e-1)" "unprognostic (1.13e-1)" "unprognostic (1.62e-1)" "unprognostic (4.59e-1)" "unprognostic (1.45e-1)" "unprognostic (2.95e-3)" "unprognostic (6.67e-2)" "unprognostic (8.41e-2)" "unprognostic (1.10e-1)" "unprognostic (7.62e-2)" "unprognostic (2.96e-1)" "unprognostic (1.49e-1)" "unprognostic (3.60e-1)" "potential prognostic favorable (2.44e-4)" BACE1 BACE ENSG00000186318 "Beta-secretase 1" P56817 11 117285232-117316259 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "brain: 113.1;pancreas: 243.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 180.1;Early spermatids: 124.6;Late spermatids: 587.5;Oligodendrocytes: 148.0;Pancreatic acinar cells: 126.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Kidney - Fibroblasts, Pancreas - Exocrine glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB016358 Approved Supported "Plasma membrane" NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 30: White matter - Myelination" "Cluster 72: Neuronal - Signal transduction" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 22 "Plasma membrane" "CAB016358: " "unprognostic (1.33e-1)" "unprognostic (1.38e-3)" "unprognostic (2.66e-1)" "potential prognostic unfavorable (7.73e-5)" "unprognostic (1.97e-1)" "unprognostic (6.10e-2)" "unprognostic (2.92e-1)" "unprognostic (1.67e-1)" "unprognostic (2.84e-1)" "unprognostic (7.17e-3)" "potential prognostic favorable (2.18e-5)" "unprognostic (5.53e-2)" "unprognostic (1.59e-2)" "unprognostic (5.19e-1)" "unprognostic (7.21e-3)" "unprognostic (8.41e-2)" "unprognostic (7.63e-2)" "unprognostic (2.46e-1)" "unprognostic (4.56e-2)" "unprognostic (2.88e-1)" "unprognostic (5.67e-2)" "unprognostic (8.09e-2)" "unprognostic (2.96e-1)" "unprognostic (1.09e-1)" "unprognostic (1.44e-1)" "unprognostic (3.90e-2)" "unprognostic (3.72e-3)" "unprognostic (3.13e-2)" "unprognostic (1.83e-1)" "unprognostic (1.32e-1)" "unprognostic (1.78e-1)" BACE2 "AEPLC, ALP56, CEAP1, DRAP" ENSG00000182240 "Beta-secretase 2" Q9Y5Z0 21 41167801-41282530 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 21.6" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 693.6;Endometrial glandular cells: 655.1;Mast cells: 602.1;Melanocytes: 670.0;Pancreatic acinar cells: 1345.9;Prostatic club cells: 838.8;Salivary acinar cells: 589.0;Syncytiotrophoblasts: 1235.3" "Cell type enhanced" "Detected in many" "endothelial cell: 303.0;mammillary body: 188.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 2.9;eosinophil: 5.2" "Lineage enriched" "Detected in single" 8 "granulocytes: 5.2" "Cancer enhanced" "Detected in many" "skin cancer: 55.9" "Adipose visceral - Adipose progenitor cells, Lung - Fibroblasts_2, Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035416 Approved "Intracellular and membrane" Enzyme NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 60: Stomach - Digestion" "Cluster 27: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 16 "HPA035416: " "unprognostic (6.70e-2)" "unprognostic (4.87e-3)" "unprognostic (1.30e-3)" "potential prognostic unfavorable (1.63e-7)" "unprognostic (4.25e-2)" "unprognostic (5.03e-2)" "unprognostic (1.90e-3)" "unprognostic (1.70e-2)" "unprognostic (2.24e-2)" "unprognostic (2.59e-1)" "validated prognostic unfavorable (3.45e-5)" "validated prognostic unfavorable (8.43e-4)" "unprognostic (5.00e-2)" "unprognostic (1.33e-2)" "unprognostic (5.13e-2)" "unprognostic (5.88e-3)" "unprognostic (1.88e-1)" "unprognostic (2.39e-2)" "unprognostic (2.87e-2)" "unprognostic (1.27e-2)" "unprognostic (8.13e-2)" "unprognostic (7.93e-2)" "unprognostic (2.82e-2)" "unprognostic (1.10e-1)" "unprognostic (3.73e-1)" "unprognostic (8.54e-2)" "unprognostic (3.24e-1)" "unprognostic (1.34e-1)" "unprognostic (1.45e-1)" "unprognostic (4.71e-2)" "unprognostic (7.46e-2)" BACH1 "BACH-1, BTBD24" ENSG00000156273 "BTB domain and CNC homolog 1" O14867 21 29194071-29630751 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 84.3" "Cell type enhanced" "Detected in all" "Late spermatids: 651.8;monocytes: 779.7;Neutrophils: 948.0;Podocytes: 816.6" "Cell type enhanced" "Detected in all" "midbrain-derived inhibitory: 670.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 151.1" "Group enriched" "Detected in all" 4 "granulocytes: 151.1;monocytes: 51.3" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034949 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 69: Skin cancer - ECM organization" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 54 Nucleoplasm Cytosol "HPA034949: " "unprognostic (1.05e-1)" "unprognostic (2.41e-2)" "unprognostic (3.39e-1)" "unprognostic (1.84e-3)" "unprognostic (2.98e-1)" "unprognostic (1.73e-2)" "unprognostic (2.13e-1)" "unprognostic (2.22e-1)" "unprognostic (2.06e-1)" "unprognostic (4.87e-2)" "unprognostic (3.75e-2)" "unprognostic (3.12e-1)" "unprognostic (9.27e-3)" "unprognostic (2.26e-3)" "unprognostic (5.26e-3)" "unprognostic (3.91e-3)" "unprognostic (2.36e-3)" "unprognostic (1.80e-1)" "unprognostic (1.22e-1)" "unprognostic (6.18e-3)" "unprognostic (3.29e-2)" "potential prognostic unfavorable (7.45e-4)" "unprognostic (7.55e-3)" "unprognostic (6.35e-2)" "unprognostic (2.37e-1)" "unprognostic (1.03e-1)" "unprognostic (1.02e-1)" "unprognostic (5.60e-2)" "unprognostic (1.59e-1)" "unprognostic (7.53e-3)" "unprognostic (4.50e-2)" BACH2 BTBD25 ENSG00000112182 "BTB domain and CNC homolog 2" Q9BYV9 6 89926528-90296843 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 6.9;lymphoid tissue: 16.3" "Cell type enhanced" "Detected in many" "B-cells: 2052.5;Cone photoreceptor cells: 722.5;Epididymal basal cells: 765.8;Innate lymphoid cells: 908.4;T-cells: 574.9;Thymocytes: 669.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 4.8" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in many" 4 "lymphoma: 35.5" "Minor Salivary Gland - Minor salivary glandular cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051384, HPA058384" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 34: B-cells - Unknown function" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 11: White matter - Signal transduction" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 59 Nucleoplasm Cytosol "HPA051384: , HPA058384: " "unprognostic (1.23e-1)" "unprognostic (1.33e-1)" "unprognostic (2.13e-1)" "unprognostic (4.13e-2)" "unprognostic (7.32e-2)" "unprognostic (9.58e-2)" "unprognostic (3.09e-2)" "unprognostic (3.50e-2)" "unprognostic (2.21e-3)" "unprognostic (5.22e-2)" "unprognostic (3.15e-1)" BAD "BBC2, BCL2L8" ENSG00000002330 "BCL2 associated agonist of cell death" Q92934 11 64269830-64284704 "Cancer-related genes, Predicted intracellular proteins, RAS pathway related proteins" Apoptosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 357.1;Extravillous trophoblasts: 259.2;Syncytiotrophoblasts: 285.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004205, HPA028185, HPA062105" Approved Enhanced "Mitochondria,Principal piece,End piece" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." 44 Mitochondria "Principal piece, End piece" "CAB004205: , HPA028185: , HPA062105: " "unprognostic (1.47e-1)" "unprognostic (2.04e-1)" "unprognostic (9.12e-3)" "unprognostic (1.00e-1)" "unprognostic (7.81e-2)" "unprognostic (2.16e-1)" "unprognostic (1.03e-1)" "unprognostic (4.12e-2)" "unprognostic (7.32e-2)" "unprognostic (3.48e-3)" "unprognostic (1.11e-1)" "unprognostic (1.01e-2)" "unprognostic (3.14e-2)" "potential prognostic unfavorable (2.68e-4)" "unprognostic (2.32e-1)" "unprognostic (2.77e-2)" "unprognostic (5.59e-2)" "unprognostic (9.61e-2)" "unprognostic (4.46e-1)" "unprognostic (2.36e-1)" "unprognostic (5.29e-2)" "unprognostic (2.27e-1)" "unprognostic (1.91e-1)" "unprognostic (8.96e-2)" "unprognostic (2.72e-1)" "unprognostic (3.90e-1)" "unprognostic (1.15e-1)" "unprognostic (4.50e-1)" "unprognostic (1.04e-1)" "unprognostic (1.30e-1)" "unprognostic (2.40e-1)" BAG1 ENSG00000107262 "BAG cochaperone 1" Q99933 9 33247820-33264720 "Cancer-related genes, Predicted intracellular proteins" Apoptosis Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 1284.5;Late spermatids: 4335.2;Ocular epithelial cells: 786.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002486, HPA018121, HPA073236" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 47: Endothelial cells - Vasculature" "Cluster 7: Liver cancer - Metabolism" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 51 Nucleoplasm Cytosol "CAB002486: , HPA018121: , HPA073236: " "unprognostic (4.13e-3)" "unprognostic (2.18e-2)" "unprognostic (5.14e-2)" "unprognostic (3.52e-1)" "unprognostic (2.40e-1)" "unprognostic (1.16e-2)" "unprognostic (4.40e-1)" "unprognostic (1.59e-2)" "unprognostic (3.80e-3)" "unprognostic (1.70e-1)" "validated prognostic favorable (6.64e-12)" "validated prognostic favorable (4.44e-6)" "potential prognostic favorable (2.22e-8)" "unprognostic (3.36e-1)" "unprognostic (6.27e-3)" "unprognostic (1.23e-1)" "unprognostic (5.53e-2)" "unprognostic (1.88e-2)" "unprognostic (1.87e-1)" "unprognostic (8.85e-2)" "unprognostic (1.54e-1)" "unprognostic (1.64e-1)" "unprognostic (3.24e-1)" "unprognostic (2.52e-1)" "unprognostic (9.74e-2)" "potential prognostic unfavorable (8.01e-5)" "unprognostic (1.92e-1)" "unprognostic (9.52e-2)" "unprognostic (1.95e-1)" "unprognostic (3.83e-2)" "potential prognostic favorable (2.05e-4)" BAG2 ENSG00000112208 "BAG cochaperone 2" O95816 6 57172326-57189833 "Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 101.3;Decidual stromal cells: 154.4;Early spermatids: 129.0;Late primary spermatocytes: 276.1;Oocytes: 92.1;Smooth muscle cells: 203.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Colon - Smooth muscle cells, Minor Salivary Gland - Endothelial cells, Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018862, HPA019918" Enhanced Approved "Centrosome,Basal body,Cytosol,Mid piece,Principal piece" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 31: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 160 Cytosol "Centrosome, Basal body, Mid piece, Principal piece" "HPA018862: , HPA019918: " "unprognostic (5.39e-3)" "unprognostic (3.37e-1)" "unprognostic (1.48e-1)" "unprognostic (9.68e-2)" "unprognostic (2.48e-1)" "unprognostic (1.36e-1)" "unprognostic (9.44e-2)" "unprognostic (8.47e-2)" "unprognostic (2.79e-2)" "unprognostic (2.44e-2)" "unprognostic (1.13e-3)" "unprognostic (5.85e-2)" "unprognostic (6.68e-3)" "validated prognostic unfavorable (3.75e-7)" "validated prognostic unfavorable (5.22e-6)" "potential prognostic unfavorable (9.05e-4)" "unprognostic (5.35e-2)" "unprognostic (1.06e-1)" "unprognostic (1.19e-1)" "unprognostic (5.59e-3)" "unprognostic (5.53e-2)" "unprognostic (7.53e-2)" "unprognostic (8.48e-2)" "unprognostic (2.68e-2)" "unprognostic (8.89e-3)" "unprognostic (7.43e-2)" "potential prognostic unfavorable (1.48e-4)" "unprognostic (3.28e-3)" "unprognostic (2.80e-1)" "potential prognostic unfavorable (1.93e-5)" "unprognostic (6.98e-2)" BAG3 ENSG00000151929 "BAG cochaperone 3" O95817 10 119651380-119677819 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Apoptosis Chaperone "Cardiomyopathy, Charcot-Marie-Tooth disease, Disease variant, Myofibrillar myopathy, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 489.5" "Cell type enhanced" "Detected in many" "Epididymal efferent duct ciliated cells: 329.9;monocytes: 343.2;Pancreatic acinar cells: 323.9;Pancreatic duct cells: 591.8;Smooth muscle cells: 299.5;Thymic myoid cells: 316.8" "Cell type enhanced" "Detected in many" "astrocyte: 92.5;endothelial cell: 94.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 4.1" "Lineage enriched" "Detected in single" 6 "T-cells: 4.1" "Low cancer specificity" "Detected in all" "Kidney - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018493, HPA020586" Enhanced Supported "Nucleoplasm,Basal body,Cytosol" NA NA 200000 "Cluster 31: T-cells - T-cell receptor" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 75: Non-specific - Chaperones and protein folding" 216 Cytosol "Nucleoplasm, Basal body" "HPA018493: , HPA020586: " "unprognostic (6.29e-2)" "unprognostic (6.15e-2)" "unprognostic (7.41e-2)" "unprognostic (1.57e-1)" "unprognostic (9.56e-2)" "unprognostic (4.02e-2)" "unprognostic (5.04e-2)" "unprognostic (1.11e-1)" "unprognostic (1.22e-2)" "unprognostic (1.75e-1)" "potential prognostic favorable (6.13e-8)" "unprognostic (4.04e-2)" "unprognostic (2.02e-1)" "potential prognostic unfavorable (2.21e-4)" "unprognostic (4.63e-2)" "unprognostic (3.92e-3)" "potential prognostic unfavorable (5.92e-7)" "unprognostic (9.94e-2)" "unprognostic (8.98e-2)" "unprognostic (4.88e-3)" "unprognostic (5.68e-2)" "unprognostic (2.41e-3)" "unprognostic (6.78e-3)" "unprognostic (2.63e-1)" "unprognostic (2.60e-2)" "unprognostic (1.09e-1)" "unprognostic (7.91e-2)" "unprognostic (5.84e-2)" "unprognostic (5.15e-2)" "unprognostic (3.42e-2)" "unprognostic (3.09e-2)" BAG4 SODD ENSG00000156735 "BAG cochaperone 4" O95429 8 38176533-38213301 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophil progenitors: 117.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013716, HPA018951" Approved NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 40: Non-specific - Unknown function" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 101 "CAB013716: , HPA018951: " "unprognostic (3.84e-3)" "unprognostic (3.73e-2)" "unprognostic (1.47e-1)" "unprognostic (4.67e-2)" "unprognostic (8.16e-2)" "unprognostic (1.41e-2)" "unprognostic (4.00e-1)" "unprognostic (2.79e-1)" "unprognostic (3.26e-2)" "unprognostic (2.68e-2)" "unprognostic (1.64e-3)" "unprognostic (1.43e-2)" "unprognostic (3.84e-2)" "unprognostic (1.00e-1)" "unprognostic (4.20e-2)" "unprognostic (1.43e-1)" "unprognostic (1.18e-1)" "unprognostic (3.33e-3)" "unprognostic (5.58e-3)" "unprognostic (4.29e-1)" "unprognostic (1.07e-3)" "unprognostic (2.54e-3)" "unprognostic (4.10e-1)" "unprognostic (1.18e-1)" "unprognostic (2.68e-2)" "unprognostic (1.26e-2)" "unprognostic (3.34e-2)" "unprognostic (1.08e-1)" "unprognostic (1.30e-2)" "unprognostic (2.06e-3)" "unprognostic (2.21e-1)" BAG5 ENSG00000166170 "BAG cochaperone 5" Q9UL15 14 103556545-103562657 "Disease related genes, Predicted intracellular proteins" Chaperone "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "testis: 119.4" "Cell type enhanced" "Detected in many" "Early spermatids: 1914.6;Late primary spermatocytes: 638.5;Late spermatids: 2665.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Minor Salivary Gland - Minor salivary gland basal cells, Spleen - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016429 Enhanced Approved "Nucleoplasm,Vesicles,Plasma membrane,Primary cilium,Primary cilium tip,Centrosome,Basal body" NA NA 9000 "Cluster 35: Neutrophils - Protein binding" "Cluster 57: Testis - Spermatogenesis" "Cluster 31: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 54 Vesicles "Nucleoplasm, Plasma membrane, Primary cilium, Primary cilium tip, Centrosome, Basal body" "HPA016429: " "unprognostic (1.87e-1)" "unprognostic (7.98e-2)" "unprognostic (9.06e-2)" "unprognostic (4.83e-2)" "unprognostic (1.68e-2)" "unprognostic (1.14e-1)" "unprognostic (2.32e-1)" "unprognostic (3.20e-2)" "unprognostic (3.12e-2)" "unprognostic (1.62e-2)" "potential prognostic favorable (5.50e-5)" "unprognostic (3.06e-3)" "unprognostic (6.16e-3)" "potential prognostic unfavorable (8.55e-4)" "unprognostic (6.05e-2)" "unprognostic (3.55e-2)" "unprognostic (1.86e-1)" "unprognostic (2.49e-1)" "unprognostic (1.82e-2)" "unprognostic (3.41e-1)" "unprognostic (1.50e-2)" "unprognostic (5.83e-2)" "unprognostic (1.16e-1)" "unprognostic (1.78e-2)" "unprognostic (1.50e-2)" "unprognostic (6.79e-2)" "unprognostic (5.04e-2)" "unprognostic (8.06e-2)" "unprognostic (1.73e-1)" "unprognostic (1.22e-2)" "unprognostic (6.65e-2)" BAG6 "BAT3, D6S52E, G3, Scythe" ENSG00000204463 "BAG cochaperone 6" P46379 6 31639028-31652705 "Predicted intracellular proteins" "Apoptosis, Differentiation, Immunity, Spermatogenesis, Transport" "Chaperone, Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 218.9;Late primary spermatocytes: 250.0;Late spermatids: 612.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020704, HPA045116, HPA053291" Enhanced Supported Nucleoplasm,Vesicles,Cytosol "Intracellular and membrane" Transport NA NA 260000 "Cluster 25: Non-specific - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 28: Non-specific - Nuclear processes" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 94 Nucleoplasm "Vesicles, Cytosol" "CAB020704: , HPA045116: , HPA053291: " "unprognostic (3.77e-1)" "unprognostic (9.53e-2)" "unprognostic (2.59e-1)" "unprognostic (2.18e-1)" "unprognostic (1.68e-1)" "unprognostic (5.18e-3)" "unprognostic (2.91e-1)" "unprognostic (1.81e-1)" "unprognostic (1.21e-1)" "unprognostic (1.34e-3)" "unprognostic (1.20e-1)" "unprognostic (4.27e-2)" "unprognostic (1.09e-2)" "potential prognostic unfavorable (6.64e-4)" "unprognostic (5.71e-2)" "unprognostic (7.55e-2)" "unprognostic (6.51e-2)" "unprognostic (5.65e-2)" "unprognostic (1.05e-1)" "unprognostic (1.66e-1)" "unprognostic (7.65e-2)" "unprognostic (8.20e-3)" "unprognostic (1.28e-2)" "unprognostic (6.72e-2)" "unprognostic (2.19e-1)" "unprognostic (1.53e-1)" "unprognostic (3.41e-1)" "unprognostic (1.72e-1)" "unprognostic (1.26e-1)" "unprognostic (1.45e-1)" BAHCC1 "BAHD2, KIAA1447" ENSG00000266074 "BAH domain and coiled-coil containing 1" Q9P281 17 81395457-81466331 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.6" "Cell type enhanced" "Detected in many" "Retinal amacrine cells: 69.6;Retinal bipolar cells: 73.8;Thymocytes: 94.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Leukemia: 25.0" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023386, HPA076910" Approved Approved Nucleoli NA NA "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 6: Leukemia - Signal transduction" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 11 Nucleoli "HPA023386: , HPA076910: " "unprognostic (1.46e-1)" "unprognostic (2.68e-1)" "unprognostic (2.52e-1)" "unprognostic (1.02e-1)" "unprognostic (1.29e-1)" "unprognostic (9.17e-2)" "unprognostic (8.70e-2)" "unprognostic (2.57e-2)" "unprognostic (3.13e-2)" "unprognostic (1.89e-2)" "unprognostic (1.07e-2)" "unprognostic (7.78e-2)" "unprognostic (1.51e-2)" "unprognostic (6.80e-3)" "unprognostic (2.81e-3)" "unprognostic (9.43e-2)" "unprognostic (1.07e-2)" "unprognostic (1.40e-1)" "unprognostic (6.70e-2)" "potential prognostic favorable (1.55e-4)" "unprognostic (2.42e-1)" "unprognostic (1.16e-1)" "unprognostic (6.54e-2)" "unprognostic (2.47e-1)" "unprognostic (3.92e-1)" "unprognostic (3.39e-2)" "unprognostic (2.54e-2)" "unprognostic (9.24e-2)" BAHD1 KIAA0945 ENSG00000140320 "Bromo adjacent homology domain containing 1" Q8TBE0 15 40439721-40468236 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041196 Supported Nucleoplasm NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 21: Testis - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 81: Alveolar cells - Lung function" 65 Nucleoplasm "HPA041196: " "unprognostic (3.82e-3)" "unprognostic (9.40e-3)" "unprognostic (2.35e-1)" "unprognostic (2.14e-2)" "unprognostic (2.54e-1)" "unprognostic (8.76e-2)" "unprognostic (3.93e-2)" "potential prognostic favorable (7.61e-4)" "unprognostic (6.27e-2)" "unprognostic (4.47e-2)" "validated prognostic favorable (8.01e-9)" "validated prognostic favorable (6.36e-5)" "unprognostic (1.48e-2)" "unprognostic (1.16e-1)" "unprognostic (4.89e-3)" "unprognostic (2.24e-2)" "unprognostic (9.67e-2)" "unprognostic (1.23e-2)" "unprognostic (3.12e-3)" "unprognostic (3.49e-2)" "unprognostic (3.06e-1)" "unprognostic (1.21e-2)" "unprognostic (2.66e-2)" "unprognostic (5.06e-2)" "unprognostic (4.14e-2)" "unprognostic (1.12e-2)" "unprognostic (4.31e-1)" "unprognostic (3.20e-1)" "unprognostic (1.74e-1)" "unprognostic (5.18e-2)" "unprognostic (2.69e-2)" BAIAP2 "BAP2, IRSp53, WAML" ENSG00000175866 "BAR/IMD domain containing adaptor protein 2" Q9UQB8 17 81035122-81117434 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 274.0;Esophageal apical cells: 653.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 21.3" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Prostate glandular cells, Skin - Keratinocyte (other), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023310, HPA027421" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA 7900 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 2: Non-specific - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 108 "Plasma membrane, Cytosol" "HPA023310: , HPA027421: " "unprognostic (1.85e-1)" "unprognostic (1.96e-1)" "unprognostic (2.33e-1)" "unprognostic (1.01e-1)" "unprognostic (3.84e-2)" "unprognostic (1.88e-1)" "unprognostic (6.16e-2)" "unprognostic (2.97e-1)" "unprognostic (1.03e-1)" "unprognostic (7.19e-2)" "unprognostic (6.47e-3)" "unprognostic (1.15e-2)" "unprognostic (7.98e-2)" "unprognostic (6.45e-3)" "unprognostic (8.32e-3)" "unprognostic (1.42e-1)" "unprognostic (4.63e-1)" "unprognostic (6.49e-2)" "unprognostic (2.63e-1)" "unprognostic (1.56e-2)" "unprognostic (5.09e-2)" "unprognostic (1.79e-1)" "unprognostic (1.18e-2)" "unprognostic (3.75e-1)" "unprognostic (2.12e-1)" "unprognostic (4.13e-2)" "unprognostic (1.15e-1)" "unprognostic (9.83e-2)" "unprognostic (7.29e-2)" "unprognostic (2.01e-1)" "unprognostic (3.94e-2)" BAIAP2L1 IRTKS ENSG00000006453 "BAR/IMD domain containing adaptor protein 2 like 1" Q9UHR4 7 98291650-98401090 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 55.5" "Cell type enhanced" "Detected in many" "Foveolar cells: 734.9;Oocytes: 584.8;Pancreatic acinar cells: 541.4;Papillary tip epithelial cells: 425.5;Urothelial cells: 786.5" "Cell type enhanced" "Detected in all" "endothelial cell: 63.4;pericyte: 45.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA019484, HPA021257, HPA023874, HPA029503" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 17: Intestine - Digestion" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 39: Non-specific - Transcription" "Cluster 68: Foveolar cells - Mucosal defense" 30 "Plasma membrane" Cytosol "HPA019484: , HPA021257: , HPA023874: , HPA029503: " "unprognostic (1.67e-1)" "unprognostic (1.39e-1)" "unprognostic (7.53e-2)" "potential prognostic unfavorable (1.37e-4)" "unprognostic (9.02e-2)" "unprognostic (1.16e-1)" "unprognostic (1.38e-2)" "unprognostic (1.26e-2)" "validated prognostic unfavorable (1.69e-6)" "validated prognostic unfavorable (1.02e-4)" "unprognostic (8.24e-2)" "unprognostic (1.59e-2)" "unprognostic (9.20e-3)" "unprognostic (2.81e-2)" "unprognostic (1.25e-3)" "unprognostic (2.56e-1)" "unprognostic (6.78e-2)" "unprognostic (1.32e-1)" "unprognostic (2.24e-1)" "unprognostic (1.00e-3)" "unprognostic (2.37e-2)" "unprognostic (7.22e-2)" "unprognostic (1.63e-1)" "unprognostic (9.10e-2)" "unprognostic (1.43e-1)" "unprognostic (5.22e-2)" "unprognostic (3.16e-1)" "unprognostic (7.67e-2)" "unprognostic (3.35e-1)" BAIAP2L2 "FLJ22582, pinkbar" ENSG00000128298 "BAR/IMD domain containing adaptor protein 2 like 2" Q6UXY1 22 38084652-38111015 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 92.8;kidney: 36.3" "Cell type enhanced" "Detected in many" "Enterocytes: 211.1;Esophageal apical cells: 304.0;Leydig cells: 111.8;Peritubular myoid cells: 92.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 53.7" "Kidney - Proximal tubular cells, Prostate - Prostate glandular cells" "Region enhanced" "Detected in many" "olfactory bulb: 3.7" "Low region specificity" "Detected in many" HPA003043 Approved NA NA "Cluster 77: Intestine - Digestion" "Cluster 53: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 84: Apical squamous epithelium - Cornification" "HPA003043: " "unprognostic (1.32e-2)" "unprognostic (2.08e-1)" "unprognostic (5.29e-2)" "unprognostic (7.63e-2)" "unprognostic (7.50e-2)" "unprognostic (2.10e-1)" "unprognostic (1.70e-1)" "validated prognostic favorable (3.78e-4)" "validated prognostic favorable (3.74e-4)" "unprognostic (3.33e-2)" "unprognostic (2.65e-3)" "potential prognostic unfavorable (1.37e-4)" "potential prognostic unfavorable (1.78e-4)" "unprognostic (3.93e-2)" "unprognostic (1.81e-1)" "unprognostic (1.33e-1)" "unprognostic (6.58e-2)" "unprognostic (2.47e-1)" "unprognostic (9.83e-3)" "unprognostic (1.24e-1)" "unprognostic (1.03e-1)" "unprognostic (9.79e-3)" "unprognostic (1.82e-3)" "unprognostic (1.25e-1)" "unprognostic (7.70e-2)" BAIAP3 "BAP3, KIAA0734" ENSG00000007516 "BAI1 associated protein 3" O94812 16 1333638-1349441 "Predicted intracellular proteins" "Exocytosis, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "brain: 135.9;pituitary gland: 360.8" "Cell type enhanced" "Detected in many" "Corticotrophs: 140.9;Ependymal cells: 273.7;Epididymal efferent duct ciliated cells: 94.0;Fallopian tube ciliated cells: 95.9;Gonadotrophs: 75.4;Lactotrophs: 200.7;Other brain neurons: 113.7;Pituitary stem cells: 136.1;Respiratory ciliated cells: 58.7;Somatotrophs: 212.3;Thyrotrophs: 163.5" "Cell type enhanced" "Detected in all" "ependymal cell: 326.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.6" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal medulla cells, Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Pancreas - Beta cells, Prostate - Prostate basal glandular cells, Stomach - Gastric enteroendocrine cells, Thyroid gland - T-cells" "Region enhanced" "Detected in many" "hypothalamus: 123.4" "Region enhanced" "Detected in all" "hypothalamus: 90.3" "HPA015627, HPA015979" Uncertain Supported NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 20: Pituitary gland - Hormone signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 70: DU4475 - Unknown function" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 3 "HPA015627: , HPA015979: " "unprognostic (1.66e-1)" "unprognostic (7.63e-2)" "unprognostic (1.42e-1)" "unprognostic (4.68e-2)" "unprognostic (3.88e-2)" "unprognostic (5.77e-3)" "unprognostic (7.54e-2)" "unprognostic (1.73e-1)" "unprognostic (7.35e-2)" "unprognostic (2.83e-1)" "potential prognostic favorable (1.67e-5)" "unprognostic (3.13e-2)" "unprognostic (1.30e-1)" "unprognostic (1.66e-1)" "unprognostic (2.32e-1)" "unprognostic (1.52e-1)" "unprognostic (9.25e-2)" "unprognostic (1.83e-1)" "unprognostic (7.33e-3)" "unprognostic (2.58e-1)" "unprognostic (1.12e-1)" "unprognostic (1.12e-2)" "unprognostic (1.65e-1)" "unprognostic (2.43e-1)" "unprognostic (7.28e-2)" "unprognostic (6.00e-3)" "unprognostic (4.18e-1)" "unprognostic (3.71e-1)" "unprognostic (3.42e-3)" "unprognostic (2.53e-2)" BAK1 "BAK, BCL2L7, CDN1" ENSG00000030110 "BCL2 antagonist/killer 1" Q16611 6 33572547-33580293 "Predicted membrane proteins, Transporters" "Apoptosis, Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 43.8;Enterocytes: 55.4;Esophageal apical cells: 39.9;Esophageal basal cells: 41.3;Esophageal suprabasal cells: 40.3;Extravillous trophoblasts: 40.2;Megakaryocytes: 61.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005029 Enhanced NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 35 "CAB005029: " "unprognostic (3.49e-3)" "unprognostic (3.07e-1)" "unprognostic (3.02e-3)" "unprognostic (3.30e-2)" "unprognostic (1.11e-2)" "unprognostic (1.67e-1)" "unprognostic (7.27e-2)" "unprognostic (1.02e-1)" "unprognostic (3.92e-3)" "unprognostic (1.07e-2)" "unprognostic (5.08e-2)" "unprognostic (1.04e-2)" "unprognostic (2.08e-1)" "validated prognostic unfavorable (7.83e-5)" "validated prognostic unfavorable (1.68e-5)" "potential prognostic unfavorable (5.71e-5)" "unprognostic (6.94e-2)" "unprognostic (2.07e-1)" "unprognostic (3.64e-1)" "unprognostic (1.69e-1)" "unprognostic (3.14e-1)" "unprognostic (6.76e-3)" "unprognostic (4.20e-1)" "unprognostic (1.46e-1)" "unprognostic (2.06e-1)" "unprognostic (1.61e-1)" "unprognostic (1.30e-1)" "unprognostic (1.89e-1)" "unprognostic (3.74e-2)" "unprognostic (2.35e-2)" "unprognostic (9.01e-2)" BAMBI NMA ENSG00000095739 "BMP and activin membrane bound inhibitor" Q13145 10 28677510-28682932 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 290.5;Breast myoepithelial cells: 106.8;Breast secretory cells: 185.0;Epididymal basal cells: 93.9;Epididymal efferent duct absorptive cells: 107.9;Granulosa cells: 83.5;Müller glia: 96.4;Platelets: 100.5" "Group enriched" "Detected in many" 6 "astrocyte: 25.7;committed oligodendrocyte precursor: 82.3;endothelial cell: 76.5;ependymal cell: 46.4;oligodendrocyte: 25.7;oligodendrocyte precursor cell: 75.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 329.6" "Adrenal gland - Adrenal cortex cells, Lung - Fibroblasts_1, Pituitary gland - Fibroblasts, Skin - Hair cortex cells, Skin - Inner root sheath cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010819, HPA010866" Approved Approved "Nucleoli fibrillar center,Vesicles,Lipid droplets" NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 30: White matter - Myelination" "Cluster 32: Non-specific - Cell proliferation" "Cluster 108: Fibroblasts - ECM organization" 2 Vesicles "Nucleoli fibrillar center, Lipid droplets" "HPA010819: , HPA010866: " "unprognostic (2.92e-2)" "unprognostic (2.54e-3)" "unprognostic (2.82e-1)" "unprognostic (1.26e-1)" "unprognostic (2.94e-1)" "potential prognostic unfavorable (7.95e-4)" "unprognostic (1.61e-1)" "unprognostic (7.22e-3)" "unprognostic (2.90e-1)" "unprognostic (1.65e-1)" "unprognostic (1.48e-3)" "unprognostic (1.28e-3)" "potential prognostic favorable (1.50e-4)" "potential prognostic unfavorable (1.01e-5)" "unprognostic (8.07e-3)" "unprognostic (1.08e-2)" "unprognostic (1.29e-1)" "unprognostic (2.83e-1)" "unprognostic (3.22e-1)" "unprognostic (8.55e-2)" "unprognostic (2.53e-2)" "unprognostic (7.99e-3)" "unprognostic (1.61e-1)" "unprognostic (3.45e-2)" "unprognostic (5.25e-2)" "unprognostic (6.35e-2)" "unprognostic (5.03e-2)" "unprognostic (6.16e-2)" "unprognostic (3.45e-1)" "unprognostic (2.08e-2)" "unprognostic (8.20e-3)" BANF1 BAF ENSG00000175334 "BAF nuclear assembly factor 1" O75531 11 66002228-66004149 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" DNA-binding "Disease variant, Osteoporosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 294.2;Oocytes: 478.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB032896, HPA039242" Enhanced Supported Nucleoplasm,Cytosol NA NA 270000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 44 Nucleoplasm Cytosol "CAB032896: , HPA039242: " "unprognostic (5.52e-3)" "unprognostic (4.77e-2)" "unprognostic (1.57e-1)" "unprognostic (3.00e-2)" "unprognostic (5.41e-2)" "unprognostic (4.21e-2)" "unprognostic (3.44e-1)" "unprognostic (1.63e-1)" "unprognostic (1.45e-3)" "unprognostic (3.66e-1)" "validated prognostic unfavorable (6.39e-5)" "validated prognostic unfavorable (3.54e-4)" "unprognostic (7.33e-2)" "unprognostic (2.39e-3)" "unprognostic (1.01e-2)" "potential prognostic unfavorable (2.08e-5)" "unprognostic (5.37e-3)" "unprognostic (4.90e-3)" "unprognostic (2.48e-1)" "unprognostic (1.63e-1)" "unprognostic (4.78e-2)" "unprognostic (4.24e-3)" "unprognostic (1.49e-2)" "unprognostic (9.33e-2)" "unprognostic (3.20e-1)" "unprognostic (3.19e-1)" "unprognostic (5.16e-2)" "unprognostic (8.55e-2)" "unprognostic (4.15e-1)" "unprognostic (2.11e-2)" "unprognostic (1.24e-1)" BANF2 "BAF-L, BAF2, BAFL, C20orf179, dJ803K15.1" ENSG00000125888 "BANF family member 2" Q9H503 20 17693672-17735871 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 106.6" "Group enriched" "Detected in some" 17 "Early spermatids: 1121.0;Late spermatids: 4210.1" "Cell type enhanced" "Detected in single" "choroid plexus epithelial cell: 2.4" "Cancer enhanced" "Detected in single" "Liver Hepatocellular Carcinoma (TCGA): 1.0" "Region enhanced" "Detected in single" "choroid plexus: 2.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA042635 Approved NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 21: Non-specific - Metabolism" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 1 "HPA042635: " "unprognostic (2.50e-1)" BANK1 "BANK, FLJ20706" ENSG00000153064 "B cell scaffold protein with ankyrin repeats 1" Q8NDB2 4 101411286-102074812 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "B-cell activation" "Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 90.3" "Cell type enriched" "Detected in many" 8 "B-cells: 2483.0" "Cell type enhanced" "Detected in many" "leukocyte: 90.2" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 18.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 14 "memory B-cell: 311.4;naive B-cell: 254.2" "Lineage enriched" "Detected in many" 16 "B-cells: 311.4" "Cancer enhanced" "Detected in many" "Leukemia: 10.5;lymphoma: 18.1;Myeloma: 11.7" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Prostate - Prostate glandular cells, Skeletal muscle - Macrophages, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA037002 Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 35: Non-specific - DNA binding" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 6 "Plasma membrane, Cytosol" Nucleoplasm "HPA037002: " "unprognostic (1.58e-2)" "unprognostic (1.18e-2)" "unprognostic (1.18e-2)" "potential prognostic favorable (1.44e-5)" "unprognostic (1.90e-2)" "unprognostic (4.79e-2)" "unprognostic (1.13e-3)" "unprognostic (2.75e-2)" "potential prognostic unfavorable (5.82e-4)" "potential prognostic favorable (1.27e-6)" "unprognostic (1.92e-1)" "unprognostic (2.17e-1)" "unprognostic (1.68e-3)" "unprognostic (1.73e-1)" "unprognostic (3.93e-2)" "unprognostic (2.37e-2)" "unprognostic (3.28e-2)" "unprognostic (6.55e-2)" "unprognostic (4.96e-2)" "unprognostic (7.05e-3)" "unprognostic (8.99e-2)" "unprognostic (1.57e-1)" "unprognostic (8.52e-2)" "unprognostic (3.25e-1)" "unprognostic (3.93e-2)" "unprognostic (1.53e-2)" "unprognostic (1.24e-1)" BANP "BEND1, DKFZp761H172, FLJ10177, FLJ20538, SMAR1, SMARBP1" ENSG00000172530 "BTG3 associated nuclear protein" Q8N9N5 16 87949244-88077318 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation" "Chromatin regulator, Developmental protein, DNA-binding, Repressor, RNA-binding" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Somatotrophs: 259.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047164 Approved Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 49: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 103: Non-specific - Basic cellular processes" 83 Nucleoplasm "Nuclear bodies" "HPA047164: " "unprognostic (1.94e-1)" "unprognostic (9.39e-2)" "unprognostic (2.61e-1)" "unprognostic (1.04e-2)" "unprognostic (1.30e-2)" "unprognostic (2.26e-1)" "unprognostic (1.63e-1)" "potential prognostic favorable (1.02e-4)" "unprognostic (3.02e-2)" "unprognostic (1.38e-1)" "unprognostic (1.23e-2)" "unprognostic (3.41e-2)" "unprognostic (1.19e-1)" "validated prognostic unfavorable (9.42e-4)" "validated prognostic unfavorable (1.05e-5)" "unprognostic (2.08e-2)" "unprognostic (1.29e-1)" "unprognostic (1.20e-1)" "unprognostic (2.35e-1)" "unprognostic (1.26e-1)" "unprognostic (8.97e-2)" "unprognostic (7.67e-3)" "potential prognostic unfavorable (7.63e-4)" "unprognostic (1.61e-2)" "unprognostic (1.11e-2)" "unprognostic (2.19e-1)" "unprognostic (1.80e-2)" "unprognostic (6.30e-2)" "unprognostic (1.53e-2)" "potential prognostic unfavorable (5.52e-4)" "unprognostic (1.55e-1)" BAP1 "hucep-6, KIAA0272, UCHL2" ENSG00000163930 "BRCA1 associated protein 1" Q92560 3 52401008-52410008 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Differentiation, Ubl conjugation pathway" "Chromatin regulator, Developmental protein, Hydrolase, Protease, Thiol protease" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 108.8;Late primary spermatocytes: 65.9;Late spermatids: 61.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004322, HPA028814, HPA028815, HPA055560" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 67: Testis - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 139 Nucleoplasm Cytosol "CAB004322: , HPA028814: , HPA028815: , HPA055560: " "unprognostic (1.90e-1)" "unprognostic (3.72e-1)" "unprognostic (3.09e-1)" "unprognostic (1.54e-1)" "unprognostic (2.91e-2)" "unprognostic (1.32e-1)" "unprognostic (1.53e-1)" "unprognostic (1.66e-1)" "unprognostic (4.46e-2)" "unprognostic (7.10e-2)" "unprognostic (2.25e-2)" "unprognostic (2.01e-2)" "unprognostic (2.41e-3)" "unprognostic (2.26e-3)" "unprognostic (2.68e-2)" "unprognostic (2.30e-2)" "unprognostic (2.91e-2)" "unprognostic (1.29e-2)" "unprognostic (2.31e-3)" "unprognostic (5.17e-1)" "unprognostic (8.68e-2)" "unprognostic (7.46e-3)" "unprognostic (9.82e-2)" "unprognostic (3.93e-3)" "unprognostic (4.55e-2)" "unprognostic (3.19e-2)" "unprognostic (3.58e-2)" "unprognostic (1.41e-1)" "unprognostic (1.66e-1)" "unprognostic (5.86e-2)" "unprognostic (3.20e-2)" BARD1 ENSG00000138376 "BRCA1 associated RING domain 1" Q99728 2 214725646-214809683 "Cancer-related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 148.4;Monocyte progenitors: 166.3;Neutrophil progenitors: 168.1;Suprabasal keratinocytes: 140.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast myoepithelial cells, Testis - Spermatocytes, Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB034106, HPA035354, HPA044864" Enhanced Supported "Nucleoplasm,Nuclear speckles,Cytoplasmic bodies" No Yes "Cluster 5: Non-specific - Cell proliferation" "Cluster 49: Non-specific - Transcription" "Cluster 19: Astrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Non-specific - Cell proliferation" 102 "Nucleoplasm, Nuclear speckles" "Cytoplasmic bodies" "CAB034106: , HPA035354: , HPA044864: " "unprognostic (6.83e-3)" "unprognostic (2.35e-1)" "unprognostic (1.62e-1)" "unprognostic (2.37e-1)" "unprognostic (1.74e-2)" "unprognostic (4.37e-2)" "unprognostic (3.74e-2)" "unprognostic (9.99e-2)" "unprognostic (3.66e-3)" "unprognostic (3.26e-2)" "unprognostic (3.08e-1)" "potential prognostic unfavorable (5.35e-5)" "unprognostic (8.62e-2)" "unprognostic (1.93e-3)" "unprognostic (1.93e-3)" "potential prognostic favorable (9.55e-4)" "unprognostic (1.62e-1)" "unprognostic (9.38e-2)" "unprognostic (3.91e-1)" "unprognostic (1.09e-2)" "unprognostic (4.83e-2)" "unprognostic (3.60e-2)" "unprognostic (6.54e-2)" "unprognostic (3.86e-2)" "unprognostic (1.99e-2)" "unprognostic (2.22e-1)" "unprognostic (1.37e-1)" "unprognostic (2.63e-1)" "unprognostic (1.77e-2)" BARHL1 ENSG00000125492 "BarH like homeobox 1" Q9BZE3 9 132582606-132590252 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 328 "brain: 32.8" "Group enriched" "Detected in some" 5 "Brain excitatory neurons: 7.0;Mesothelial cells: 7.0" "Group enriched" "Detected in some" 19 "lower rhombic lip: 34.0;upper rhombic lip: 17.7" "Not detected" "Not detected" "Region enhanced" "Detected in many" "pons: 72.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "cerebellum: 3.2;midbrain: 2.4;pons and medulla: 1.1" "Region enhanced" "Detected in many" "cerebellum: 8.6" NA NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 49: Hindbrain - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 2: Cerebellar granular cells - Neuronal signaling" BARHL2 ENSG00000143032 "BarH like homeobox 2" Q9NY43 1 90711539-90717302 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "brain: 42.1" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 9.0;Differentiating spermatogonia: 3.7;Early primary spermatocytes: 5.1;Parietal cells: 3.5;Retinal amacrine cells: 25.2;Retinal ganglion cells: 3.9;Retinal horizontal cells: 40.1;Undifferentiated spermatogonia: 9.6" "Cell type enriched" "Detected in some" 8 "upper rhombic lip: 19.4" "Not detected" "Not detected" "Region enriched" "Detected in many" 13 "cerebellum: 56.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 29 "Bone cancer: 20.7" "Testis - Spermatogonia" "Region enriched" "Detected in many" 5 "cerebellum: 12.9" "Region enriched" "Detected in some" 20 "cerebellum: 36.9" NA NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 2 BARX1 ENSG00000131668 "BARX homeobox 1" Q9HBU1 9 93951627-93955355 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "stomach 1: 158.3" "Cell type enhanced" "Detected in some" "Early spermatids: 3.5;Fibroblasts: 11.8;Gastric chief cells: 2.2;Pericytes: 2.0;Salivary basal cells: 3.7;Salivary duct cells: 1.4;Salivary ionocytes: 2.2;Undifferentiated spermatogonia: 2.0;Vascular smooth muscle cells: 16.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Stomach Adenocarcinoma (TCGA): 35.1" "Region enriched" "Detected in single" 4 "amygdala: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA055858 Approved Nucleoplasm,Vesicles NA NA "Cluster 60: Stomach - Digestion" "Cluster 51: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 62: Smooth muscle cells - Muscle contraction" Nucleoplasm Vesicles "HPA055858: " "unprognostic (7.16e-2)" "unprognostic (2.86e-3)" "unprognostic (2.80e-1)" "unprognostic (2.43e-1)" "unprognostic (2.55e-3)" "potential prognostic unfavorable (2.09e-4)" "unprognostic (1.38e-2)" "unprognostic (4.92e-2)" "unprognostic (3.34e-2)" "unprognostic (3.03e-2)" "unprognostic (6.57e-2)" "unprognostic (1.22e-3)" "unprognostic (7.87e-2)" "unprognostic (7.69e-3)" "unprognostic (4.51e-2)" "unprognostic (1.34e-1)" "unprognostic (1.08e-1)" "potential prognostic unfavorable (5.12e-4)" BARX2 ENSG00000043039 "BARX homeobox 2" Q9UMQ3 11 129375848-129452279 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 142.8;salivary gland: 123.8;vagina: 66.3" "Cell type enhanced" "Detected in many" "Breast secretory cells: 222.5;Esophageal apical cells: 362.6;Esophageal basal cells: 193.1;Esophageal suprabasal cells: 515.9;Lacrimal acinar cells: 1026.3;Pancreatic duct cells: 306.1;Salivary acinar cells: 667.0;Salivary duct cells: 249.9;Salivary ionocytes: 296.4;Salivary myoepithelial cells: 201.6;Suprabasal keratinocytes: 284.4" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 94.6;deep-layer near-projecting: 32.2;ependymal cell: 63.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Skin - Outer root sheath cells, Stomach - Gastric mucous cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "cerebral cortex: 4.1;hippocampal formation: 2.4" "CAB033311, HPA064966, HPA068414" Enhanced Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 21: Non-specific - Metabolism" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 2 Nucleoplasm "Golgi apparatus, Cytosol" "CAB033311: , HPA064966: , HPA068414: " "unprognostic (2.54e-2)" "unprognostic (1.98e-1)" "unprognostic (2.14e-1)" "unprognostic (1.01e-1)" "unprognostic (1.40e-1)" "unprognostic (1.18e-2)" "unprognostic (1.98e-1)" "unprognostic (2.15e-1)" "validated prognostic favorable (1.45e-4)" "validated prognostic favorable (8.61e-4)" "unprognostic (3.85e-3)" "unprognostic (2.96e-1)" "unprognostic (3.18e-3)" "potential prognostic unfavorable (1.27e-4)" "unprognostic (2.57e-2)" "unprognostic (2.34e-2)" "unprognostic (3.77e-2)" "unprognostic (1.66e-1)" "unprognostic (4.98e-3)" "unprognostic (5.25e-2)" "unprognostic (1.40e-1)" "unprognostic (2.19e-1)" "unprognostic (2.99e-2)" "unprognostic (2.32e-1)" "unprognostic (3.43e-1)" "unprognostic (1.62e-1)" "unprognostic (3.58e-3)" BASP1 "CAP-23, CAP23, NAP-22, NAP22" ENSG00000176788 "Brain abundant membrane attached signal protein 1" P80723 5 17065598-17276843 "Plasma proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 379.7;epididymis: 286.2" "Cell type enriched" "Detected in many" 4 "Neutrophils: 6905.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "neutrophil: 128.9" "Lineage enriched" "Detected in many" 16 "granulocytes: 128.9" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 573.1" "Adipose subcutaneous - Adipose progenitor cells, Prostate - Prostate glandular cells, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045218, HPA050333" Enhanced Supported "Plasma membrane" NA NA 49000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 22: Epididymis - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 18 "Plasma membrane" "HPA045218: , HPA050333: " "unprognostic (2.73e-1)" "unprognostic (9.10e-3)" "unprognostic (1.81e-1)" "unprognostic (2.28e-2)" "unprognostic (2.97e-1)" "unprognostic (1.47e-1)" "unprognostic (1.31e-1)" "unprognostic (7.33e-3)" "unprognostic (1.16e-3)" "unprognostic (1.97e-1)" "potential prognostic unfavorable (2.38e-8)" "unprognostic (1.11e-2)" "unprognostic (2.36e-2)" "unprognostic (1.94e-1)" "unprognostic (1.51e-2)" "unprognostic (5.34e-2)" "unprognostic (3.61e-1)" "unprognostic (1.26e-2)" "unprognostic (1.55e-2)" "unprognostic (1.70e-1)" "unprognostic (2.11e-1)" "unprognostic (1.49e-1)" "unprognostic (7.98e-3)" "unprognostic (1.44e-1)" "unprognostic (3.12e-3)" "unprognostic (3.57e-1)" "unprognostic (4.97e-1)" "potential prognostic unfavorable (8.18e-4)" "unprognostic (1.25e-1)" "unprognostic (3.55e-2)" "unprognostic (3.47e-2)" BATF "B-ATF, BATF1, SFA-2" ENSG00000156127 "Basic leucine zipper ATF-like transcription factor" Q16520 14 75522455-75546993 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.5;lymphoid tissue: 28.7" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 344.2;Hofbauer cells: 120.4;Mast cells: 640.1;Neutrophils: 111.2;T-cells: 174.2;Urothelial cells: 151.1" "Cell type enriched" "Detected in some" 4 "leukocyte: 29.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Lineage enriched" "Detected in all" 5 "T-cells: 130.7" "Cancer enriched" "Detected in many" 4 "lymphoma: 111.4" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Breast glandular cells, Breast - Breast glandular cells, Prostate - Urothelial cells, Skeletal muscle - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA059588, HPA064962" Approved Enhanced Nucleoplasm NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 58: Mast cells - Allergic inflammatory responses" 23 Nucleoplasm "HPA059588: , HPA064962: " "unprognostic (8.64e-3)" "potential prognostic favorable (6.38e-4)" "unprognostic (7.39e-2)" "unprognostic (1.71e-3)" "unprognostic (1.36e-2)" "unprognostic (7.82e-3)" "unprognostic (1.46e-2)" "unprognostic (3.05e-1)" "potential prognostic favorable (1.03e-4)" "unprognostic (2.34e-1)" "unprognostic (1.62e-3)" "unprognostic (1.71e-1)" "unprognostic (4.76e-2)" "unprognostic (1.01e-2)" "unprognostic (3.08e-2)" "unprognostic (2.26e-2)" "unprognostic (2.12e-1)" "unprognostic (3.28e-1)" "unprognostic (1.67e-1)" "unprognostic (8.88e-2)" "unprognostic (8.53e-2)" "unprognostic (1.34e-1)" "unprognostic (2.99e-1)" "unprognostic (1.39e-1)" "unprognostic (5.87e-3)" "unprognostic (1.21e-1)" "unprognostic (3.88e-2)" "unprognostic (4.97e-2)" "unprognostic (1.77e-1)" "unprognostic (1.52e-1)" "unprognostic (1.53e-1)" BATF2 MGC20410 ENSG00000168062 "Basic leucine zipper ATF-like transcription factor 2" Q8N1L9 11 64987945-64997018 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast lactating cells: 12.9;Colonocytes: 20.6;Enteric stem cells: 12.0;Enteric transient amplifying cells: 8.2;Enterocytes: 17.5;Goblet cells: 17.2;Hofbauer cells: 9.0;Pancreatic acinar cells: 13.0" "Cell type enhanced" "Detected in some" "endothelial cell: 5.1;fibroblast: 4.9;pericyte: 6.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 2.1;intermediate monocyte: 5.3;neutrophil: 7.4;non-classical monocyte: 2.8" "Group enriched" "Detected in many" 6 "granulocytes: 7.4;monocytes: 5.3" "Cancer enriched" "Detected in many" 5 "Myeloma: 29.4" "Minor Salivary Gland - Minor salivary glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA062496 Approved Approved Nucleoli NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 60: Stomach - Digestion" "Cluster 43: Hindbrain - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 65: Non-specific - Cell growth & division" 12 Nucleoli "HPA062496: " "unprognostic (6.54e-2)" "unprognostic (1.54e-1)" "unprognostic (8.48e-3)" "unprognostic (1.34e-1)" "unprognostic (3.31e-1)" "unprognostic (9.61e-3)" "unprognostic (6.58e-2)" "unprognostic (3.91e-1)" "unprognostic (2.78e-2)" "unprognostic (1.13e-1)" "unprognostic (3.67e-2)" "unprognostic (9.22e-2)" "unprognostic (1.72e-1)" "unprognostic (1.97e-2)" "unprognostic (9.24e-2)" "unprognostic (3.37e-3)" "unprognostic (1.23e-2)" "unprognostic (1.06e-1)" "unprognostic (1.42e-1)" "unprognostic (1.17e-3)" "unprognostic (1.75e-2)" "potential prognostic unfavorable (3.71e-4)" "unprognostic (1.94e-1)" "unprognostic (2.87e-1)" "unprognostic (1.26e-1)" "unprognostic (5.83e-3)" "unprognostic (4.01e-1)" "unprognostic (4.97e-3)" "unprognostic (3.27e-2)" "unprognostic (4.87e-2)" "unprognostic (1.15e-1)" BATF3 "JDP1, JUNDM1, SNFT" ENSG00000123685 "Basic leucine zipper ATF-like transcription factor 3" Q9NR55 1 212686417-212699840 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 24.8" "Cell type enhanced" "Detected in many" "Breast lactating cells: 15.6;cDC: 73.8;Choroid plexus epithelial cells: 18.0;Extravillous trophoblasts: 58.0;Hepatic stellate cells: 12.9;Kupffer cells: 15.4;Macrophages: 19.3;Microglia: 25.5;Migrating cytotrophoblasts: 15.4;Pericytes: 25.1;Vascular smooth muscle cells: 18.7" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 31.1;choroid plexus epithelial cell: 23.1" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 16.6" "Region enhanced" "Detected in all" "choroid plexus: 16.9" "Group enriched" "Detected in many" 5 "intermediate monocyte: 65.9;myeloid DC: 55.3;non-classical monocyte: 99.6" "Group enriched" "Detected in many" 34 "dendritic cells: 55.3;monocytes: 99.6" "Group enriched" "Detected in all" 6 "Adrenocortical cancer: 24.8;lymphoma: 93.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA075858 Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 82: Dendritic cells - Antigen presentation" 37 Nucleoli "Nucleoplasm, Cytosol" "HPA075858: " "unprognostic (3.70e-2)" "unprognostic (2.90e-2)" "unprognostic (5.97e-3)" "unprognostic (2.79e-2)" "unprognostic (3.68e-1)" "unprognostic (2.26e-1)" "unprognostic (4.00e-2)" "unprognostic (1.77e-1)" "unprognostic (1.28e-1)" "unprognostic (1.03e-1)" "unprognostic (1.37e-1)" "unprognostic (1.79e-3)" "unprognostic (1.86e-2)" "unprognostic (1.96e-1)" "unprognostic (4.59e-2)" "unprognostic (1.06e-2)" "unprognostic (5.86e-2)" "unprognostic (2.58e-1)" "unprognostic (1.27e-1)" "unprognostic (4.61e-2)" "unprognostic (5.35e-2)" "unprognostic (1.55e-2)" "unprognostic (2.57e-1)" "unprognostic (2.19e-1)" "unprognostic (1.99e-1)" "unprognostic (4.67e-2)" "unprognostic (1.72e-1)" "unprognostic (8.27e-2)" "unprognostic (4.62e-1)" "unprognostic (3.07e-1)" BAX BCL2L4 ENSG00000087088 "BCL2 associated X, apoptosis regulator" Q07812 19 48954815-48961798 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transporters" "Apoptosis, Host-virus interaction" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 333.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004206, HPA027878, CAB080663, CAB080665" Approved Approved "Vesicles,Plasma membrane" NA NA 89000 "Cluster 25: Non-specific - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 44 Vesicles "Plasma membrane" "CAB004206: , CAB080663: , CAB080665: , HPA027878: " "unprognostic (6.41e-2)" "unprognostic (8.49e-2)" "unprognostic (3.49e-1)" "unprognostic (1.31e-1)" "unprognostic (2.10e-3)" "unprognostic (3.33e-2)" "unprognostic (9.10e-2)" "unprognostic (2.53e-2)" "unprognostic (1.00e-1)" "unprognostic (4.00e-1)" "unprognostic (1.15e-3)" "unprognostic (2.83e-1)" "unprognostic (9.74e-2)" "potential prognostic unfavorable (6.91e-5)" "unprognostic (8.53e-3)" "unprognostic (1.18e-1)" "unprognostic (3.81e-1)" "unprognostic (1.06e-1)" "unprognostic (2.49e-1)" "unprognostic (1.75e-1)" "unprognostic (1.08e-1)" "unprognostic (9.09e-2)" "unprognostic (6.66e-2)" "unprognostic (8.33e-2)" "unprognostic (3.62e-1)" "unprognostic (4.69e-2)" "unprognostic (2.68e-1)" "unprognostic (1.02e-1)" "unprognostic (2.41e-1)" "unprognostic (2.94e-2)" "unprognostic (2.08e-3)" BAZ1A "ACF1, hACF1, WALp1, WCRF180" ENSG00000198604 "Bromodomain adjacent to zinc finger domain 1A" Q9NRL2 14 34752731-34875647 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 70.4" "Cell type enhanced" "Detected in many" "Early spermatids: 760.9;Neutrophil progenitors: 1072.2;Neutrophils: 2072.2" "Cell type enhanced" "Detected in all" "leukocyte: 228.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 29.5" "Lineage enriched" "Detected in all" 4 "granulocytes: 29.5" "Low cancer specificity" "Detected in all" "Liver - Neutrophils, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA002730 Supported NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 11: White matter - Signal transduction" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 24: Neutrophils - Innate immunity signal integration" 39 "HPA002730: " "unprognostic (1.91e-1)" "unprognostic (2.69e-1)" "potential prognostic favorable (2.09e-4)" "unprognostic (5.34e-2)" "unprognostic (2.62e-2)" "unprognostic (1.39e-1)" "unprognostic (2.58e-1)" "potential prognostic favorable (7.63e-5)" "unprognostic (1.68e-1)" "potential prognostic unfavorable (6.95e-4)" "unprognostic (1.22e-1)" "unprognostic (2.42e-1)" "unprognostic (3.14e-2)" "potential prognostic unfavorable (9.10e-5)" "unprognostic (1.90e-1)" "unprognostic (1.87e-1)" "unprognostic (2.03e-3)" "unprognostic (7.31e-2)" "unprognostic (4.06e-2)" "unprognostic (1.30e-1)" "unprognostic (4.95e-2)" "potential prognostic unfavorable (1.46e-4)" "unprognostic (1.92e-3)" "unprognostic (2.75e-2)" "unprognostic (1.10e-1)" "unprognostic (6.20e-2)" "unprognostic (3.96e-2)" "unprognostic (1.24e-1)" "unprognostic (9.13e-2)" "unprognostic (2.36e-1)" "unprognostic (3.05e-1)" BAZ1B "WBSCR10, WBSCR9, WSTF" ENSG00000009954 "Bromodomain adjacent to zinc finger domain 1B" Q9UIG0 7 73440406-73522293 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, Transcription, Transcription regulation" "Kinase, Transferase, Tyrosine-protein kinase" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037081, CAB037158, HPA058068" Supported Supported Nucleoplasm NA NA 4000 "Cluster 30: Non-specific - DNA binding" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 39: Non-specific - Transcription" "Cluster 27: Non-specific - Cell proliferation" 56 Nucleoplasm "CAB037081: , CAB037158: , HPA058068: " "unprognostic (1.79e-2)" "unprognostic (8.09e-2)" "unprognostic (1.90e-1)" "unprognostic (1.10e-2)" "unprognostic (3.67e-1)" "unprognostic (1.03e-2)" "unprognostic (2.20e-1)" "unprognostic (1.67e-2)" "unprognostic (2.87e-1)" "potential prognostic unfavorable (3.06e-4)" "potential prognostic favorable (1.88e-4)" "unprognostic (1.01e-2)" "unprognostic (1.12e-1)" "unprognostic (2.23e-3)" "unprognostic (2.44e-3)" "unprognostic (1.58e-2)" "unprognostic (1.91e-1)" "unprognostic (2.48e-2)" "unprognostic (1.39e-1)" "unprognostic (7.14e-2)" "unprognostic (1.53e-1)" "unprognostic (5.78e-2)" "unprognostic (6.05e-3)" "unprognostic (1.28e-1)" "unprognostic (1.14e-1)" "unprognostic (1.54e-2)" "unprognostic (1.81e-1)" "unprognostic (1.41e-1)" "unprognostic (4.82e-2)" "unprognostic (6.49e-2)" "unprognostic (4.28e-1)" BAZ2A "KIAA0314, TIP5, WALp3" ENSG00000076108 "Bromodomain adjacent to zinc finger domain 2A" Q9UIF9 12 56595596-56636816 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005782, HPA063806" Enhanced "Nuclear speckles" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 6: Non-specific - Immune response" "Cluster 38: Non-specific - Transcription" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 10 "Nuclear speckles" "HPA005782: , HPA063806: " "unprognostic (7.99e-2)" "unprognostic (7.63e-2)" "unprognostic (5.33e-3)" "unprognostic (2.03e-3)" "unprognostic (2.65e-1)" "unprognostic (5.94e-2)" "unprognostic (2.42e-1)" "unprognostic (4.02e-1)" "unprognostic (1.48e-1)" "unprognostic (1.53e-2)" "unprognostic (1.26e-3)" "potential prognostic favorable (1.47e-4)" "unprognostic (4.03e-2)" "unprognostic (2.86e-3)" "unprognostic (3.65e-1)" "unprognostic (2.85e-1)" "unprognostic (7.40e-2)" "unprognostic (7.21e-2)" "unprognostic (2.32e-1)" "unprognostic (2.81e-2)" "unprognostic (2.36e-2)" "unprognostic (3.15e-2)" "potential prognostic unfavorable (1.63e-4)" "unprognostic (1.63e-1)" "unprognostic (9.57e-2)" "unprognostic (9.74e-2)" "unprognostic (7.40e-2)" "unprognostic (1.29e-1)" "unprognostic (1.56e-1)" "unprognostic (3.37e-2)" "unprognostic (6.96e-2)" BAZ2B WALp4 ENSG00000123636 "Bromodomain adjacent to zinc finger domain 2B" Q9UIF8 2 159318979-159616569 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 1302.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 101.9;neutrophil: 197.0" "Lineage enriched" "Detected in all" 8 "granulocytes: 197.0" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019819, HPA059292" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 61: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 12 Nucleoplasm Cytosol "HPA019819: , HPA059292: " "unprognostic (3.04e-2)" "unprognostic (8.53e-2)" "unprognostic (4.77e-2)" "unprognostic (2.40e-1)" "unprognostic (2.59e-1)" "unprognostic (1.99e-1)" "unprognostic (1.17e-1)" "unprognostic (5.50e-2)" "unprognostic (4.95e-2)" "unprognostic (2.49e-1)" "potential prognostic favorable (1.93e-4)" "unprognostic (1.80e-2)" "unprognostic (8.36e-2)" "unprognostic (2.40e-1)" "unprognostic (9.60e-3)" "unprognostic (3.33e-2)" "unprognostic (2.99e-1)" "unprognostic (7.01e-2)" "unprognostic (1.35e-1)" "unprognostic (1.78e-2)" "unprognostic (9.60e-2)" "unprognostic (1.00e-1)" "unprognostic (9.08e-3)" "unprognostic (6.30e-1)" "unprognostic (5.73e-2)" "unprognostic (1.37e-1)" "unprognostic (1.05e-1)" "unprognostic (2.15e-1)" "unprognostic (2.35e-1)" "unprognostic (7.93e-2)" "unprognostic (3.96e-1)" BBC3 "JFY1, PUMA" ENSG00000105327 "BCL2 binding component 3" "Q96PG8, Q9BXH1" 19 47220822-47232766 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 75.9;Breast secretory cells: 93.6;Endometrial secretory cells: 97.6;Epididymal basal cells: 259.1;Epididymal clear cells: 93.9;Fallopian secretory cells: 120.3;Pancreatic duct cells: 74.7;Platelets: 92.0;Suprabasal keratinocytes: 91.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 4.6;neutrophil: 3.4" "Lineage enriched" "Detected in single" 7 "granulocytes: 4.6" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB007752, HPA070403" Approved Approved Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 24: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 25: Non-specific - Ribosome" "Cluster 51: Secretory epithelial cells - Mixed function" 25 Cytosol "CAB007752: , HPA070403: " "potential prognostic favorable (2.95e-4)" "unprognostic (3.59e-2)" "unprognostic (2.31e-2)" "unprognostic (3.85e-2)" "unprognostic (1.28e-1)" "unprognostic (5.75e-2)" "unprognostic (2.07e-2)" "unprognostic (1.76e-2)" "unprognostic (1.88e-2)" "unprognostic (3.18e-2)" "unprognostic (1.87e-1)" "unprognostic (7.78e-2)" "unprognostic (2.22e-3)" "unprognostic (6.53e-2)" "unprognostic (1.10e-1)" "unprognostic (1.13e-1)" "unprognostic (3.74e-1)" "unprognostic (8.92e-2)" "unprognostic (4.07e-1)" "unprognostic (2.85e-2)" "unprognostic (6.84e-3)" "unprognostic (4.22e-2)" "unprognostic (3.28e-2)" "unprognostic (2.22e-1)" "unprognostic (1.65e-1)" "unprognostic (1.09e-2)" "unprognostic (3.20e-1)" "unprognostic (1.40e-3)" "unprognostic (1.73e-1)" "unprognostic (3.27e-1)" "unprognostic (4.06e-2)" BBIP1 "bA348N5.3, BBIP10, BBS18, NCRNA00081" ENSG00000214413 "BBSome interacting protein 1" A8MTZ0 10 110898730-110919201 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Transport" "Bardet-Biedl syndrome, Ciliopathy, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 95.9" "Cell type enhanced" "Detected in many" "Early spermatids: 531.4;Late primary spermatocytes: 1004.5;Late spermatids: 695.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055206, HPA075343" Approved Approved "Nucleoplasm,Vesicles,Centrosome,Basal body,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 67: Testis - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 2 "Nucleoplasm, Basal body, Cytosol" "Vesicles, Centrosome" "HPA055206: , HPA075343: " "unprognostic (1.07e-1)" "unprognostic (3.22e-3)" "unprognostic (3.47e-2)" "unprognostic (4.65e-2)" "unprognostic (2.42e-2)" "unprognostic (1.06e-1)" "unprognostic (3.18e-2)" "unprognostic (1.38e-3)" "unprognostic (1.23e-2)" "potential prognostic favorable (2.28e-6)" "unprognostic (2.63e-2)" "unprognostic (2.02e-1)" "unprognostic (7.87e-3)" "unprognostic (1.36e-1)" "unprognostic (1.14e-1)" "unprognostic (3.21e-1)" "unprognostic (1.10e-1)" "unprognostic (3.15e-1)" "unprognostic (2.32e-1)" "unprognostic (6.96e-2)" "unprognostic (2.15e-1)" "unprognostic (1.47e-2)" "unprognostic (3.99e-1)" "unprognostic (1.68e-1)" "unprognostic (2.06e-1)" "unprognostic (1.57e-1)" "unprognostic (8.57e-3)" "unprognostic (4.53e-2)" "unprognostic (1.27e-1)" "unprognostic (3.36e-2)" BBLN "C9orf16, EST00098, FLJ12823, MGC4639" ENSG00000171159 "Bublin coiled coil protein" Q9BUW7 9 128160265-128163924 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 619.0" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 947.6;Late spermatids: 1588.9;Megakaryocytes: 574.9;Platelets: 825.1;Prostatic hillock cells: 609.3;Urothelial cells: 658.9" "Cell type enhanced" "Detected in all" "hippocampal CA4: 346.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Urothelial cells" "Low region specificity" "Detected in all" HPA020725 Uncertain Approved Microtubules NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 51: Neurons - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 13 Microtubules "HPA020725: " "unprognostic (2.25e-1)" "unprognostic (1.55e-1)" "unprognostic (3.17e-1)" "unprognostic (1.00e-3)" "unprognostic (1.22e-2)" "unprognostic (7.37e-3)" "unprognostic (3.06e-1)" "unprognostic (1.43e-1)" "unprognostic (7.96e-2)" "unprognostic (1.62e-2)" "potential prognostic unfavorable (2.55e-4)" "unprognostic (1.93e-1)" "unprognostic (1.26e-2)" "potential prognostic unfavorable (3.44e-5)" "unprognostic (2.29e-1)" "unprognostic (4.76e-2)" "unprognostic (1.58e-1)" "unprognostic (1.06e-1)" "unprognostic (3.88e-1)" "unprognostic (7.87e-2)" "unprognostic (8.44e-2)" "unprognostic (4.56e-2)" "unprognostic (2.78e-2)" "unprognostic (1.61e-1)" "unprognostic (2.22e-3)" "unprognostic (4.97e-3)" "unprognostic (1.83e-1)" "unprognostic (4.61e-2)" "unprognostic (6.94e-2)" "unprognostic (1.61e-2)" "unprognostic (1.38e-1)" BBOF1 "C14orf45, CCDC176, FBB10" ENSG00000119636 "Basal body orientation factor 1" Q8ND07 14 74019349-74082863 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 36.1" "Cell type enhanced" "Detected in many" "Early spermatids: 231.6;Endometrial ciliated cells: 352.6;Ependymal cells: 264.8;Epididymal efferent duct ciliated cells: 324.0;Fallopian tube ciliated cells: 304.8;Late primary spermatocytes: 418.2;Respiratory ciliated cells: 421.4" "Cell type enhanced" "Detected in all" "ependymal cell: 282.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA003090, HPA003136, HPA075108" Approved Approved "Nucleoplasm,Plasma membrane,Centriolar satellite,Cytosol" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" 1 Nucleoplasm "Plasma membrane, Centriolar satellite, Cytosol" "HPA003090: , HPA003136: , HPA075108: " "unprognostic (7.78e-2)" "unprognostic (1.99e-1)" "unprognostic (3.12e-2)" "unprognostic (1.27e-1)" "unprognostic (9.78e-2)" "unprognostic (6.96e-2)" "unprognostic (4.61e-3)" "unprognostic (8.05e-2)" "unprognostic (7.32e-3)" "potential prognostic favorable (4.29e-6)" "unprognostic (1.38e-2)" "unprognostic (4.32e-3)" "unprognostic (1.18e-3)" "unprognostic (1.88e-1)" "unprognostic (4.21e-1)" "unprognostic (1.24e-1)" "unprognostic (1.01e-1)" "unprognostic (7.06e-2)" "unprognostic (4.40e-2)" "unprognostic (6.91e-2)" "unprognostic (1.83e-1)" "unprognostic (2.06e-1)" "unprognostic (3.02e-1)" "unprognostic (9.70e-2)" "unprognostic (1.38e-1)" "unprognostic (7.13e-2)" "unprognostic (2.55e-1)" "unprognostic (9.42e-2)" "unprognostic (2.18e-1)" BBOX1 "BBH, BBOX, G-BBH, gamma-BBH" ENSG00000129151 "Gamma-butyrobetaine hydroxylase 1" O75936 11 27040725-27127809 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carnitine biosynthesis" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "kidney: 436.5;liver: 123.3" "Cell type enhanced" "Detected in many" "Astrocytes: 122.3;Breast secretory cells: 72.8;Ependymal cells: 223.1;Epicardial cells: 122.8;Esophageal suprabasal cells: 79.3;Fallopian tube ciliated cells: 62.5;Loop of henle epithelial cells: 159.8;Proximal tubule cells: 350.2;Suprabasal keratinocytes: 61.8" "Group enriched" "Detected in many" 47 "astrocyte: 172.2;Bergmann glia: 66.5;ependymal cell: 264.9" "Group enriched" "Detected in many" 9 "Glioblastoma Multiforme (TCGA): 53.1;Kidney Renal Clear Cell Carcinoma (TCGA): 158.9;Kidney Renal Papillary Cell Carcinoma (TCGA): 124.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 10.2" "Breast - Breast glandular cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Pituitary gland - Corticotropes, Skin - Keratinocyte (other), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007600, HPA027823" Enhanced Approved Uncertain "Vesicles,Actin filaments" NA NA 23000 "Cluster 72: Kidney - Transmembrane transport" "Cluster 46: Brainstem - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 11 Vesicles "Actin filaments" "HPA007600: , HPA027823: " "unprognostic (4.94e-2)" "unprognostic (6.68e-3)" "unprognostic (7.83e-2)" "unprognostic (5.08e-3)" "unprognostic (4.84e-2)" "unprognostic (7.52e-2)" "unprognostic (2.38e-1)" "validated prognostic favorable (2.09e-11)" "validated prognostic favorable (1.28e-4)" "unprognostic (1.38e-3)" "unprognostic (9.94e-3)" "potential prognostic favorable (7.66e-4)" "unprognostic (2.20e-2)" "unprognostic (1.78e-1)" "unprognostic (3.80e-2)" "unprognostic (1.66e-1)" "unprognostic (2.87e-1)" "unprognostic (3.23e-2)" "potential prognostic unfavorable (4.52e-5)" "unprognostic (7.02e-2)" "unprognostic (1.93e-1)" "unprognostic (3.83e-1)" "unprognostic (4.16e-2)" BBS1 FLJ23590 ENSG00000174483 "Bardet-Biedl syndrome 1" Q8NFJ9 11 66510606-66533613 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Olfaction, Protein transport, Sensory transduction, Transport, Vision" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Intellectual disability, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 17 "Astrocytes: 35.8;Bergmann glia: 41.5;Brain excitatory neurons: 35.2;Brain inhibitory neurons: 37.7;Choroid plexus epithelial cells: 51.0;Ependymal cells: 65.3;Microglia: 20.7;Oligodendrocyte progenitor cells: 20.4;Oligodendrocytes: 18.4;Other brain neurons: 32.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058283 Uncertain Uncertain Midbody Yes NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 65: Brain - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 24: Non-specific - Unknown function" "Cluster 22: Non-specific - Basic cellular functions" 35 Midbody "HPA058283: " "unprognostic (9.17e-2)" "unprognostic (9.33e-2)" "unprognostic (4.09e-1)" "unprognostic (2.74e-1)" "unprognostic (2.39e-1)" "unprognostic (1.47e-1)" "unprognostic (9.38e-2)" "unprognostic (1.12e-1)" "unprognostic (7.85e-2)" "unprognostic (6.01e-2)" "potential prognostic favorable (7.01e-10)" "unprognostic (1.68e-3)" "potential prognostic favorable (7.69e-4)" "unprognostic (1.30e-1)" "unprognostic (3.50e-2)" "unprognostic (8.12e-2)" "unprognostic (3.86e-2)" "unprognostic (2.77e-2)" "unprognostic (1.60e-1)" "unprognostic (6.34e-2)" "unprognostic (1.81e-1)" "unprognostic (1.95e-1)" "unprognostic (5.10e-2)" "unprognostic (1.16e-1)" "unprognostic (8.54e-2)" "unprognostic (1.52e-1)" "unprognostic (3.25e-2)" "unprognostic (9.13e-2)" "unprognostic (2.05e-1)" "unprognostic (3.33e-1)" "unprognostic (7.71e-2)" BBS10 "C12orf58, FLJ23560" ENSG00000179941 "Bardet-Biedl syndrome 10" Q8TAM1 12 76344474-76348415 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" Chaperone "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Intellectual disability, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Thymic myoid cells: 25.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058743 Approved NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 17: Non-specific - RNA processing" 4 "HPA058743: " "unprognostic (7.78e-2)" "unprognostic (6.74e-2)" "potential prognostic unfavorable (9.03e-5)" "unprognostic (2.55e-1)" "unprognostic (2.61e-1)" "unprognostic (1.89e-2)" "unprognostic (3.65e-3)" "unprognostic (1.17e-1)" "unprognostic (6.79e-2)" "unprognostic (3.50e-3)" "potential prognostic favorable (5.12e-5)" "unprognostic (1.06e-1)" "unprognostic (2.33e-2)" "unprognostic (7.13e-3)" "unprognostic (3.38e-1)" "unprognostic (2.98e-1)" "unprognostic (3.07e-1)" "unprognostic (2.35e-2)" "unprognostic (2.32e-1)" "unprognostic (4.52e-2)" "unprognostic (1.56e-2)" "unprognostic (9.07e-2)" "unprognostic (1.13e-2)" "unprognostic (5.42e-2)" "unprognostic (7.76e-2)" "unprognostic (1.05e-1)" "unprognostic (4.79e-2)" "unprognostic (5.71e-2)" "unprognostic (1.28e-1)" "unprognostic (2.63e-1)" "unprognostic (2.52e-1)" BBS12 "C4orf24, FLJ35630, FLJ41559" ENSG00000181004 "Bardet-Biedl syndrome 12" Q6ZW61 4 122732702-122744942 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Intellectual disability, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 16.3" "Cell type enhanced" "Detected in many" "Early spermatids: 27.0;Late primary spermatocytes: 103.5;Respiratory ciliated cells: 24.4;Rod photoreceptor cells: 41.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061856 Approved NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 79: Photoreceptor cells - Phototransduction" 6 "HPA061856: " "unprognostic (5.73e-2)" "unprognostic (2.88e-1)" "unprognostic (1.67e-2)" "unprognostic (5.91e-2)" "unprognostic (2.01e-1)" "unprognostic (2.45e-2)" "unprognostic (1.26e-1)" "unprognostic (4.13e-2)" "unprognostic (2.47e-2)" "unprognostic (2.58e-1)" "validated prognostic favorable (7.00e-9)" "validated prognostic favorable (1.44e-5)" "potential prognostic favorable (8.46e-4)" "unprognostic (3.71e-2)" "unprognostic (3.37e-2)" "unprognostic (7.25e-2)" "unprognostic (6.74e-2)" "unprognostic (1.79e-2)" "unprognostic (7.50e-3)" "unprognostic (1.59e-1)" "unprognostic (1.73e-1)" "unprognostic (7.56e-2)" "unprognostic (7.63e-2)" "unprognostic (4.66e-2)" "unprognostic (1.78e-1)" "unprognostic (5.47e-2)" "unprognostic (1.00e-1)" "unprognostic (1.33e-1)" "unprognostic (1.12e-1)" BBS2 BBS ENSG00000125124 "Bardet-Biedl syndrome 2" Q9BXC9 16 56465640-56582667 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Sensory transduction, Transport, Vision" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Intellectual disability, Obesity, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 221.5;Bergmann glia: 288.9;Brain inhibitory neurons: 77.4;Ependymal cells: 110.0;Epicardial cells: 286.5;Oligodendrocyte progenitor cells: 137.7;Oligodendrocytes: 140.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040961, HPA041315, HPA059900" Approved Approved "Vesicles,Primary cilium transition zone" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 28: Astrocytes - Homeostasis & neuron support" 40 Vesicles "Primary cilium transition zone" "HPA040961: , HPA041315: , HPA059900: " "unprognostic (9.39e-2)" "unprognostic (1.54e-1)" "unprognostic (1.12e-1)" "unprognostic (1.04e-1)" "unprognostic (8.44e-2)" "unprognostic (1.09e-1)" "unprognostic (8.92e-2)" "unprognostic (9.99e-2)" "unprognostic (3.00e-2)" "unprognostic (1.23e-1)" "potential prognostic favorable (3.81e-5)" "unprognostic (3.86e-2)" "potential prognostic favorable (2.86e-5)" "unprognostic (2.42e-2)" "unprognostic (1.89e-1)" "unprognostic (1.17e-1)" "unprognostic (7.91e-2)" "unprognostic (1.68e-1)" "unprognostic (1.59e-1)" "unprognostic (1.71e-1)" "unprognostic (5.43e-3)" "unprognostic (8.43e-2)" "unprognostic (3.40e-1)" "unprognostic (4.84e-1)" "unprognostic (9.17e-2)" "unprognostic (8.49e-2)" "unprognostic (3.55e-1)" "unprognostic (2.22e-1)" "unprognostic (1.92e-1)" "unprognostic (1.33e-1)" "unprognostic (3.69e-2)" BBS4 ENSG00000140463 "Bardet-Biedl syndrome 4" Q96RK4 15 72686179-72738475 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Sensory transduction, Transport, Vision" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Intellectual disability, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 151.1;Early primary spermatocytes: 122.1;Rod photoreceptor cells: 142.5;Thyrotrophs: 130.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039418 Approved Approved "Cytosol,Acrosome,Perinuclear theca,Flagellar centriole,Principal piece,Annulus" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 44: Non-specific - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" 36 "Cytosol, Flagellar centriole, Principal piece" "Acrosome, Perinuclear theca, Annulus" "HPA039418: " "unprognostic (1.31e-1)" "unprognostic (1.12e-1)" "unprognostic (7.74e-2)" "unprognostic (4.93e-2)" "unprognostic (4.00e-1)" "unprognostic (1.92e-1)" "unprognostic (3.27e-1)" "unprognostic (1.28e-1)" "unprognostic (1.54e-1)" "unprognostic (1.76e-2)" "unprognostic (2.14e-1)" "unprognostic (4.82e-3)" "unprognostic (1.70e-3)" "unprognostic (8.80e-3)" "unprognostic (1.68e-1)" "unprognostic (9.82e-2)" "unprognostic (2.06e-1)" "unprognostic (1.77e-1)" "unprognostic (9.58e-3)" "unprognostic (3.84e-1)" "unprognostic (9.81e-2)" "unprognostic (2.00e-3)" "unprognostic (6.99e-3)" "unprognostic (1.27e-1)" "unprognostic (2.10e-1)" "unprognostic (3.97e-1)" "unprognostic (7.46e-2)" "unprognostic (1.90e-1)" "unprognostic (1.44e-1)" "unprognostic (7.05e-2)" "unprognostic (1.84e-2)" BBS5 DKFZp762I194 ENSG00000163093 "Bardet-Biedl syndrome 5" Q8N3I7 2 169479480-169506655 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Sensory transduction, Transport, Vision" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Intellectual disability, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 31.9;Bergmann glia: 34.7;Brain excitatory neurons: 41.2;Brain inhibitory neurons: 41.7;Choroid plexus epithelial cells: 60.1;Early spermatids: 172.8;Ependymal cells: 129.1;Late primary spermatocytes: 248.6;Late spermatids: 33.0;Oligodendrocyte progenitor cells: 25.3;Oligodendrocytes: 26.8;Other brain neurons: 38.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046125 Uncertain Supported "Primary cilium,Basal body,Cytosol,Acrosome,Perinuclear theca" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 26 "Basal body, Cytosol, Acrosome" "Primary cilium, Perinuclear theca" "HPA046125: " "unprognostic (2.45e-1)" "unprognostic (3.77e-3)" "unprognostic (2.56e-2)" "unprognostic (5.21e-2)" "unprognostic (8.30e-2)" "unprognostic (6.46e-3)" "unprognostic (4.50e-2)" "unprognostic (9.22e-2)" "unprognostic (2.73e-1)" "unprognostic (9.99e-2)" "unprognostic (1.75e-3)" "unprognostic (2.74e-2)" "unprognostic (1.22e-1)" "unprognostic (1.32e-1)" "potential prognostic favorable (1.71e-4)" "unprognostic (7.00e-2)" "unprognostic (2.95e-1)" "unprognostic (1.81e-1)" "unprognostic (1.20e-2)" "unprognostic (1.07e-1)" "unprognostic (1.55e-1)" "unprognostic (5.15e-3)" "unprognostic (7.54e-3)" "unprognostic (3.05e-1)" "unprognostic (5.90e-2)" "unprognostic (2.15e-3)" "unprognostic (1.77e-2)" "unprognostic (2.95e-1)" "unprognostic (2.21e-1)" "unprognostic (9.60e-2)" "unprognostic (6.11e-2)" BBS7 "BBS2L1, FLJ10715" ENSG00000138686 "Bardet-Biedl syndrome 7" Q8IWZ6 4 121824329-121870487 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Sensory transduction, Transport, Vision" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Intellectual disability, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 52.4" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 151.1;Rod photoreceptor cells: 219.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044592 Approved NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 37: Neurons - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 79: Photoreceptor cells - Phototransduction" 31 "HPA044592: " "unprognostic (3.67e-1)" "unprognostic (8.09e-2)" "unprognostic (3.97e-1)" "unprognostic (1.40e-1)" "unprognostic (8.56e-2)" "unprognostic (4.79e-2)" "unprognostic (8.53e-2)" "unprognostic (1.87e-1)" "unprognostic (1.36e-1)" "unprognostic (4.13e-2)" "validated prognostic favorable (1.37e-5)" "validated prognostic favorable (9.71e-4)" "unprognostic (1.60e-1)" "unprognostic (1.82e-3)" "unprognostic (6.43e-2)" "unprognostic (4.34e-2)" "unprognostic (4.23e-3)" "unprognostic (2.16e-1)" "unprognostic (2.57e-1)" "unprognostic (8.18e-3)" "unprognostic (8.28e-3)" "unprognostic (6.79e-2)" "unprognostic (8.71e-3)" "unprognostic (1.56e-2)" "potential prognostic favorable (9.56e-4)" "unprognostic (9.76e-3)" "unprognostic (3.15e-1)" "unprognostic (1.50e-1)" "unprognostic (1.61e-1)" "unprognostic (5.08e-2)" "unprognostic (1.69e-1)" BBS9 "B1, PTHB1" ENSG00000122507 "Bardet-Biedl syndrome 9" Q3SYG4 7 33109557-33877180 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Sensory transduction, Transport, Vision" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Intellectual disability, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Choroid plexus epithelial cells: 908.0;Ependymal cells: 962.2;Lactotrophs: 1852.4;Respiratory ciliated cells: 858.3;Rod photoreceptor cells: 1440.7;Somatotrophs: 1336.9;Thyrotrophs: 1421.0" "Cell type enhanced" "Detected in all" "endothelial cell: 1945.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021289 Uncertain Supported "Nucleoplasm,Vesicles,Primary cilium,Primary cilium tip,Primary cilium transition zone,Cytosol,Acrosome,Equatorial segment,Flagellar centriole,Mid piece,Principal piece" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 67: Non-specific - Unknown function" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 18 "Primary cilium, Primary cilium tip, Primary cilium transition zone, Flagellar centriole, Mid piece, Principal piece" "Nucleoplasm, Vesicles, Cytosol, Acrosome, Equatorial segment" "HPA021289: " "unprognostic (2.10e-1)" "unprognostic (9.91e-3)" "unprognostic (2.04e-3)" "unprognostic (2.80e-1)" "unprognostic (1.72e-1)" "unprognostic (4.98e-2)" "unprognostic (1.34e-1)" "unprognostic (1.04e-2)" "unprognostic (2.50e-2)" "potential prognostic unfavorable (8.80e-4)" "potential prognostic favorable (7.35e-5)" "unprognostic (2.63e-2)" "unprognostic (1.05e-2)" "unprognostic (2.71e-3)" "unprognostic (6.51e-2)" "unprognostic (7.25e-2)" "unprognostic (2.35e-2)" "unprognostic (1.59e-1)" "unprognostic (3.02e-1)" "unprognostic (1.51e-1)" "unprognostic (5.02e-2)" "unprognostic (2.09e-1)" "unprognostic (1.42e-2)" "unprognostic (2.50e-2)" "unprognostic (2.18e-2)" "unprognostic (9.03e-3)" "unprognostic (4.71e-1)" "unprognostic (7.77e-2)" "unprognostic (2.42e-1)" "unprognostic (3.29e-1)" "unprognostic (3.10e-2)" BBX "HBP2, HSPC339, MDS001" ENSG00000114439 "BBX high mobility group box domain containing" Q8WY36 3 107522936-107811339 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 1387.9;Sertoli cells: 1932.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006049, HPA050646" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 63: Non-specific - Protein processing" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 6 Nucleoplasm Cytosol "HPA006049: , HPA050646: " "unprognostic (5.87e-2)" "unprognostic (1.60e-2)" "unprognostic (1.34e-1)" "unprognostic (8.88e-3)" "unprognostic (1.90e-1)" "unprognostic (8.21e-3)" "unprognostic (1.12e-1)" "unprognostic (2.22e-1)" "unprognostic (2.50e-1)" "unprognostic (2.49e-2)" "potential prognostic favorable (2.16e-5)" "unprognostic (3.45e-2)" "unprognostic (8.08e-2)" "unprognostic (1.42e-2)" "unprognostic (1.28e-1)" "unprognostic (7.13e-3)" "unprognostic (1.44e-1)" "unprognostic (8.49e-2)" "unprognostic (4.18e-2)" "unprognostic (2.04e-2)" "unprognostic (1.56e-2)" "unprognostic (3.69e-2)" "unprognostic (1.80e-2)" "unprognostic (1.55e-1)" "unprognostic (4.24e-2)" "unprognostic (2.51e-1)" "unprognostic (1.11e-1)" "unprognostic (1.46e-1)" "unprognostic (1.69e-1)" "unprognostic (3.79e-2)" "unprognostic (2.07e-2)" BCAM "CD239, LU" ENSG00000187244 "Basal cell adhesion molecule (Lutheran blood group)" P50895 19 44809071-44821421 "Blood group antigen proteins, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Blood group antigen, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 346.2;kidney: 339.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 337.9;Breast myoepithelial cells: 471.9;Cytotrophoblasts: 899.4;Fallopian secretory cells: 491.6;Migrating cytotrophoblasts: 407.4;Podocytes: 387.4;Syncytiotrophoblasts: 485.3;Transitional alveolar cells: 227.1;Vascular smooth muscle cells: 539.3" "Group enriched" "Detected in many" 9 "endothelial cell: 121.2;pericyte: 138.1;vascular associated smooth muscle cell: 296.0" "Cancer enhanced" "Detected in all" "Ovary Serous Cystadenocarcinoma (TCGA): 1417.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 1, Prostate - Prostate glandular cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005654 Enhanced Approved "Nucleoli fibrillar center" NA NA 7800000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 10 "Nucleoli fibrillar center" "HPA005654: " "unprognostic (1.39e-3)" "unprognostic (2.17e-1)" "unprognostic (2.03e-1)" "unprognostic (5.44e-2)" "unprognostic (4.88e-2)" "unprognostic (9.68e-2)" "unprognostic (1.59e-1)" "unprognostic (6.32e-3)" "unprognostic (1.98e-3)" "unprognostic (7.15e-2)" "validated prognostic favorable (5.04e-6)" "validated prognostic favorable (8.13e-4)" "unprognostic (3.91e-1)" "unprognostic (4.04e-1)" "unprognostic (9.15e-2)" "unprognostic (7.98e-3)" "unprognostic (1.01e-1)" "unprognostic (3.75e-2)" "unprognostic (5.92e-2)" "unprognostic (3.76e-2)" "unprognostic (2.65e-1)" "potential prognostic favorable (9.20e-4)" "unprognostic (1.82e-2)" "unprognostic (4.75e-2)" "unprognostic (3.96e-2)" "unprognostic (3.05e-2)" "unprognostic (1.23e-1)" "unprognostic (1.55e-2)" "unprognostic (5.55e-2)" "unprognostic (1.05e-2)" "unprognostic (1.69e-2)" BCAN "BEHAB, CSPG7, MGC13038" ENSG00000132692 Brevican Q96GW7 1 156641390-156659532 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 16 "brain: 236.6" "Group enriched" "Detected in some" 8 "Astrocytes: 169.7;Melanocytes: 336.8;Oligodendrocyte progenitor cells: 494.4;Oligodendrocytes: 154.3" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 758.0;oligodendrocyte precursor cell: 517.8" "Cancer enriched" "Detected in many" 5 "Glioblastoma Multiforme (TCGA): 904.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 24 "basophil: 7.8" "Lineage enriched" "Detected in single" 24 "granulocytes: 7.8" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal medulla cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Skin - Melanocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007865, CAB025862" Enhanced Supported "Secreted in brain" "No annotated function" NA NA 120000 "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 10 "CAB025862: , HPA007865: " "unprognostic (4.04e-2)" "unprognostic (9.50e-2)" "unprognostic (2.12e-1)" "unprognostic (2.34e-3)" "unprognostic (9.15e-2)" "unprognostic (1.28e-1)" "unprognostic (1.89e-1)" "unprognostic (1.93e-3)" "unprognostic (7.19e-2)" "unprognostic (1.50e-1)" "unprognostic (2.93e-2)" "unprognostic (8.27e-2)" "unprognostic (8.97e-3)" "unprognostic (9.50e-3)" "unprognostic (4.08e-2)" "potential prognostic unfavorable (8.84e-6)" "unprognostic (1.74e-1)" "unprognostic (5.04e-2)" "unprognostic (1.01e-1)" "unprognostic (1.59e-1)" "unprognostic (1.46e-2)" "unprognostic (1.43e-1)" "unprognostic (1.75e-1)" "unprognostic (8.78e-2)" "unprognostic (1.23e-3)" "unprognostic (7.13e-3)" "unprognostic (1.35e-1)" "unprognostic (2.11e-2)" BCAP29 "BAP29, DKFZp686M2086" ENSG00000075790 "B cell receptor associated protein 29" Q9UHQ4 7 107580246-107629170 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 55.5;Bergmann glia: 60.7;Brain excitatory neurons: 84.4;Brain inhibitory neurons: 69.3;Choroid plexus epithelial cells: 35.5;Distal convoluted tubule cells: 36.5;Ependymal cells: 39.2;Microglia: 55.1;Oligodendrocyte progenitor cells: 65.4;Oligodendrocytes: 63.1;Other brain neurons: 58.5;Papillary tip epithelial cells: 43.8;Podocytes: 49.6;Renal collecting duct intercalated cells: 83.8;Renal collecting duct principal cells: 41.4;Renal connecting tubule cells: 35.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029215, HPA049694" Supported Approved Cytosol NA NA "Cluster 32: Basophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 39: Non-specific - Transcription" "Cluster 102: Non-specific - Mixed function" 11 Cytosol "HPA029215: , HPA049694: " "unprognostic (3.60e-2)" "unprognostic (2.51e-1)" "unprognostic (1.37e-1)" "unprognostic (1.06e-1)" "unprognostic (1.56e-1)" "unprognostic (1.22e-2)" "unprognostic (2.70e-2)" "potential prognostic unfavorable (1.44e-4)" "potential prognostic unfavorable (5.96e-7)" "unprognostic (7.29e-3)" "potential prognostic favorable (1.83e-5)" "unprognostic (3.27e-2)" "unprognostic (8.34e-2)" "unprognostic (1.37e-3)" "unprognostic (1.75e-3)" "unprognostic (2.32e-2)" "unprognostic (1.18e-1)" "unprognostic (9.62e-2)" "unprognostic (1.78e-2)" "unprognostic (2.47e-1)" "unprognostic (2.18e-1)" "unprognostic (1.14e-2)" "potential prognostic unfavorable (6.13e-4)" "unprognostic (2.88e-2)" "unprognostic (2.18e-1)" "unprognostic (1.45e-3)" "unprognostic (3.77e-2)" "unprognostic (1.16e-1)" "unprognostic (6.02e-2)" "unprognostic (2.09e-2)" "unprognostic (1.91e-3)" BCAP31 "6C6-Ag, BAP31, CDM, DXS1357E" ENSG00000185825 "B cell receptor associated protein 31" P51572 X 153700492-153724565 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Apoptosis, ER-Golgi transport, Host-virus interaction, Protein transport, Transport" "Deafness, Dystonia, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 513.3;Esophageal apical cells: 501.0;Extravillous trophoblasts: 575.1;Migrating cytotrophoblasts: 475.6;Syncytiotrophoblasts: 628.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003906, CAB015350, CAB015424" Supported Approved Enhanced "Endoplasmic reticulum" NA NA 75000 "Cluster 25: Non-specific - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 45: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 139 "Endoplasmic reticulum" "CAB015350: , CAB015424: , HPA003906: " "unprognostic (3.19e-2)" "potential prognostic unfavorable (2.96e-5)" "unprognostic (1.76e-1)" "unprognostic (1.65e-1)" "unprognostic (4.49e-2)" "unprognostic (2.69e-2)" "unprognostic (3.58e-3)" "unprognostic (4.97e-2)" "potential prognostic unfavorable (8.10e-5)" "unprognostic (2.23e-2)" "unprognostic (6.46e-3)" "unprognostic (9.18e-3)" "unprognostic (3.82e-3)" "unprognostic (3.21e-3)" "unprognostic (1.58e-3)" "unprognostic (1.31e-2)" "unprognostic (1.25e-2)" "unprognostic (3.28e-1)" "unprognostic (2.81e-1)" "unprognostic (9.59e-2)" "unprognostic (2.13e-2)" "unprognostic (4.36e-1)" "unprognostic (1.46e-1)" "unprognostic (2.22e-1)" "unprognostic (2.47e-1)" "unprognostic (7.96e-2)" "unprognostic (2.62e-2)" "unprognostic (3.11e-2)" "unprognostic (7.27e-2)" "unprognostic (1.15e-1)" "unprognostic (2.46e-1)" BCAR1 "CAS, CASS1, Crkas, P130Cas" ENSG00000050820 "BCAR1 scaffold protein, Cas family member" P56945 16 75228181-75268053 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 69.2;Distal convoluted tubule cells: 39.1;Loop of henle epithelial cells: 39.3;Oligodendrocyte progenitor cells: 30.7;Oligodendrocytes: 55.0;Papillary tip epithelial cells: 29.0;Podocytes: 48.3;Proximal tubule cells: 58.2;Renal collecting duct intercalated cells: 38.0;Renal collecting duct principal cells: 29.6;Renal connecting tubule cells: 41.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000443, HPA042282, HPA063796" Approved Approved Supported "Nucleoli,Nucleoli fibrillar center,Plasma membrane,Focal adhesion sites,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" 98 "Plasma membrane, Focal adhesion sites" "Nucleoli, Nucleoli fibrillar center, Cytosol" "CAB000443: , HPA042282: , HPA063796: " "unprognostic (5.29e-2)" "unprognostic (3.91e-2)" "unprognostic (1.23e-1)" "unprognostic (2.18e-2)" "unprognostic (1.22e-1)" "unprognostic (1.19e-2)" "unprognostic (3.34e-1)" "potential prognostic favorable (5.15e-4)" "unprognostic (7.46e-3)" "unprognostic (4.58e-2)" "potential prognostic favorable (1.36e-6)" "unprognostic (1.88e-1)" "unprognostic (2.21e-2)" "potential prognostic unfavorable (1.04e-4)" "unprognostic (4.69e-2)" "unprognostic (1.11e-3)" "unprognostic (1.26e-1)" "unprognostic (1.44e-3)" "unprognostic (2.61e-1)" "unprognostic (1.38e-2)" "unprognostic (3.77e-1)" "unprognostic (2.25e-2)" "unprognostic (4.67e-3)" "unprognostic (1.14e-1)" "unprognostic (1.51e-2)" "unprognostic (2.18e-2)" "unprognostic (4.54e-2)" "unprognostic (2.17e-1)" "unprognostic (1.22e-1)" "unprognostic (1.23e-1)" "unprognostic (8.31e-2)" BCAR3 "AND-34, MIG7, NSP2, SH2D3B" ENSG00000137936 "BCAR3 adaptor protein, NSP family member" O75815 1 93561741-93847150 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bergmann glia: 273.4;Endometrial secretory cells: 277.1;Podocytes: 337.6" "Cell type enhanced" "Detected in all" "astrocyte: 259.7;Bergmann glia: 285.0;central nervous system macrophage: 248.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.0;memory B-cell: 1.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014858 Approved Approved "Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 32: Basophils - Transcription" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 44: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 51: Secretory epithelial cells - Mixed function" 21 "Plasma membrane, Cytosol" Centrosome "HPA014858: " "unprognostic (2.16e-1)" "unprognostic (4.93e-1)" "unprognostic (1.21e-2)" "unprognostic (1.96e-2)" "unprognostic (3.65e-3)" "unprognostic (3.14e-1)" "unprognostic (8.60e-2)" "unprognostic (1.92e-1)" "potential prognostic unfavorable (9.42e-4)" "unprognostic (7.55e-2)" "potential prognostic favorable (8.81e-8)" "unprognostic (1.60e-3)" "unprognostic (1.86e-1)" "potential prognostic unfavorable (2.96e-4)" "unprognostic (4.50e-2)" "potential prognostic unfavorable (1.45e-5)" "unprognostic (1.03e-1)" "unprognostic (5.56e-3)" "unprognostic (1.76e-2)" "unprognostic (1.29e-1)" "unprognostic (1.89e-1)" "validated prognostic unfavorable (3.82e-4)" "validated prognostic unfavorable (7.04e-4)" "unprognostic (3.12e-2)" "unprognostic (1.22e-1)" "unprognostic (5.36e-2)" "unprognostic (1.41e-1)" "unprognostic (1.46e-1)" "unprognostic (4.51e-2)" "unprognostic (2.33e-2)" "unprognostic (1.15e-1)" BCAS1 "AIBC1, NABC1, PMES-2" ENSG00000064787 "Brain enriched myelin associated protein 1" O75363 20 53936777-54070594 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 201.8;choroid plexus: 83.2;stomach 1: 150.9" "Cell type enhanced" "Detected in many" "Foveolar cells: 1033.2;Goblet cells: 1262.8;Oligodendrocyte progenitor cells: 741.3;Oligodendrocytes: 1972.2;Prostatic club cells: 347.2;Prostatic glandular cells: 348.0;Prostatic hillock cells: 316.5;Urothelial cells: 324.9" "Cell type enriched" "Detected in many" 5 "committed oligodendrocyte precursor: 6115.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 2.7" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "breast cancer: 48.9" "Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033558, HPA051816, HPA054745" Enhanced Approved Vesicles NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 6: Non-specific - Immune response" "Cluster 27: Breast cancer - Unknown function" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 3 Vesicles "CAB033558: , HPA051816: , HPA054745: " "potential prognostic favorable (2.20e-4)" "unprognostic (3.83e-2)" "unprognostic (2.96e-2)" "unprognostic (1.98e-1)" "unprognostic (4.80e-2)" "unprognostic (1.93e-1)" "unprognostic (9.59e-2)" "unprognostic (5.42e-2)" "unprognostic (5.63e-2)" "unprognostic (4.18e-3)" "unprognostic (2.65e-2)" "unprognostic (5.64e-2)" "unprognostic (1.38e-1)" "unprognostic (3.06e-1)" "unprognostic (1.23e-1)" "unprognostic (1.30e-2)" "unprognostic (1.57e-1)" "unprognostic (7.18e-2)" "unprognostic (1.48e-2)" "unprognostic (3.13e-2)" "unprognostic (1.32e-1)" "unprognostic (1.05e-2)" "unprognostic (3.31e-1)" "unprognostic (2.49e-1)" "unprognostic (8.70e-2)" BCAS2 "DAM1, Snt309, SPF27" ENSG00000116752 "BCAS2 pre-mRNA processing factor" O75934 1 114567557-114581629 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 409.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067881 Supported Supported "Nuclear speckles,Centrosome" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 14: Neurons - Synaptic function" "Cluster 37: Non-specific - mRNA processing" "Cluster 67: Plasma cells - Plasma cell differentiation" 148 "Nuclear speckles, Centrosome" "HPA067881: " "unprognostic (2.83e-2)" "unprognostic (1.17e-1)" "unprognostic (1.46e-2)" "unprognostic (3.59e-2)" "unprognostic (3.53e-2)" "unprognostic (1.86e-2)" "unprognostic (1.97e-1)" "unprognostic (2.30e-1)" "unprognostic (5.93e-3)" "unprognostic (5.86e-3)" "potential prognostic favorable (2.48e-8)" "unprognostic (1.62e-3)" "unprognostic (4.85e-2)" "potential prognostic unfavorable (3.55e-6)" "unprognostic (3.95e-2)" "unprognostic (5.22e-3)" "unprognostic (9.52e-3)" "unprognostic (2.51e-3)" "unprognostic (8.73e-2)" "unprognostic (2.08e-3)" "unprognostic (1.59e-1)" "unprognostic (2.39e-2)" "unprognostic (6.82e-2)" "potential prognostic unfavorable (6.58e-4)" "unprognostic (6.94e-3)" "unprognostic (3.51e-1)" "unprognostic (1.13e-1)" "unprognostic (3.76e-2)" "unprognostic (1.90e-1)" "unprognostic (1.42e-2)" "unprognostic (2.43e-1)" BCAS3 "FLJ20128, PHAF2" ENSG00000141376 "BCAS3 microtubule associated cell migration factor" Q9H6U6 17 60677453-61392838 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Angiogenesis, Transcription, Transcription regulation" "Disease variant, Intellectual disability, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Respiratory ciliated cells: 1157.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052409, HPA057289" Approved Approved Nucleoli NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 7: Non-specific - Transcription" 13 Nucleoli "HPA052409: , HPA057289: " "unprognostic (2.27e-1)" "unprognostic (1.08e-2)" "unprognostic (1.63e-2)" "unprognostic (2.80e-2)" "unprognostic (1.54e-1)" "unprognostic (1.44e-1)" "unprognostic (1.34e-1)" "unprognostic (1.38e-2)" "unprognostic (1.50e-1)" "unprognostic (2.63e-1)" "potential prognostic favorable (2.73e-7)" "unprognostic (6.14e-2)" "unprognostic (5.48e-2)" "unprognostic (1.31e-1)" "unprognostic (2.97e-2)" "unprognostic (1.89e-1)" "unprognostic (3.85e-2)" "unprognostic (1.61e-1)" "unprognostic (1.55e-3)" "unprognostic (3.00e-1)" "unprognostic (1.56e-1)" "unprognostic (7.08e-3)" "unprognostic (3.01e-3)" "unprognostic (2.58e-1)" "unprognostic (1.82e-1)" "unprognostic (6.20e-2)" "unprognostic (9.18e-2)" "unprognostic (3.87e-2)" "unprognostic (1.50e-1)" "unprognostic (1.03e-2)" "unprognostic (4.35e-1)" BCAS4 "CNOL, FLJ20495" ENSG00000124243 "Breast carcinoma amplified sequence 4" Q8TDM0 20 50794894-50877177 "Disease related genes, Predicted intracellular proteins" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 39.1" "Cell type enhanced" "Detected in many" "B-cells: 109.8;Epididymal clear cells: 57.2;Oocytes: 55.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 109.4;naive B-cell: 106.4" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "lymphoma: 117.2" "Breast - Breast glandular cells, Spleen - B-cells (Spleen), Testis - Sertoli cells" "Low region specificity" "Detected in all" HPA038812 Uncertain Approved "Intermediate filaments,Cytosol" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 29: Forebrain - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" "Intermediate filaments, Cytosol" "HPA038812: " "unprognostic (3.38e-2)" "unprognostic (3.05e-1)" "unprognostic (3.15e-1)" "unprognostic (1.18e-1)" "unprognostic (2.64e-1)" "unprognostic (1.27e-2)" "unprognostic (2.04e-1)" "unprognostic (6.90e-3)" "unprognostic (4.54e-2)" "unprognostic (5.36e-2)" "unprognostic (8.97e-2)" "unprognostic (4.45e-2)" "unprognostic (2.46e-2)" "unprognostic (3.68e-3)" "unprognostic (2.97e-3)" "unprognostic (1.05e-2)" "unprognostic (1.40e-1)" "unprognostic (1.24e-2)" "unprognostic (4.11e-2)" "unprognostic (3.51e-2)" "unprognostic (5.73e-3)" "unprognostic (5.04e-2)" "unprognostic (3.49e-2)" "unprognostic (5.36e-2)" "unprognostic (7.97e-2)" "potential prognostic favorable (1.44e-7)" "unprognostic (3.66e-1)" "unprognostic (2.43e-2)" "unprognostic (7.67e-2)" "unprognostic (2.32e-2)" "unprognostic (5.39e-2)" BCAT1 "BCATc, BCT1" ENSG00000060982 "Branched chain amino acid transaminase 1" P54687 12 24810024-24949101 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Amino-acid biosynthesis, Branched-chain amino acid biosynthesis, Lipid metabolism" "Aminotransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 54.8" "Cell type enhanced" "Detected in many" "cDC: 346.3;Early spermatids: 219.5;Endometrial luminal cells: 202.8;Lactotrophs: 234.4;Late spermatids: 541.2;Macrophages: 267.6;monocytes: 242.3;Pancreatic acinar cells: 544.5;Retinal bipolar cells: 457.9;Retinal pigment epithelial cells: 328.2;Sertoli cells: 224.0;Somatotrophs: 219.9" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 61.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 17.3" "Group enriched" "Detected in many" 10 "dendritic cells: 5.8;monocytes: 17.3" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Pituitary gland - Somatotropes, Prostate - Fibroblasts, Skeletal muscle - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048592 Uncertain NA NA 150000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 8: Pancreas - Proteolysis" "Cluster 45: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" "HPA048592: " "unprognostic (2.20e-1)" "unprognostic (2.01e-2)" "unprognostic (3.02e-1)" "potential prognostic unfavorable (2.15e-4)" "unprognostic (3.26e-2)" "unprognostic (2.53e-1)" "unprognostic (4.90e-2)" "unprognostic (1.13e-3)" "potential prognostic unfavorable (5.00e-4)" "unprognostic (1.62e-3)" "unprognostic (9.86e-3)" "unprognostic (2.57e-1)" "unprognostic (1.53e-2)" "potential prognostic unfavorable (1.55e-5)" "unprognostic (1.51e-2)" "unprognostic (1.54e-1)" "unprognostic (5.29e-2)" "unprognostic (2.40e-2)" "unprognostic (3.88e-1)" "unprognostic (1.27e-2)" "unprognostic (5.80e-3)" "unprognostic (2.52e-3)" "unprognostic (1.58e-1)" "unprognostic (2.25e-1)" "unprognostic (4.87e-2)" "unprognostic (6.73e-3)" "unprognostic (1.37e-3)" "unprognostic (9.28e-2)" "unprognostic (2.58e-2)" "unprognostic (4.06e-2)" BCAT2 "BCAM, BCATm, BCT2" ENSG00000105552 "Branched chain amino acid transaminase 2" O15382 19 48795062-48811029 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Branched-chain amino acid biosynthesis, Lipid metabolism" "Aminotransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 200.2" "Cell type enhanced" "Detected in many" "Bergmann glia: 331.2" "Cell type enhanced" "Detected in all" "Bergmann glia: 379.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054091 Enhanced Approved Nucleoplasm,Mitochondria NA NA 20000 "Cluster 13: Non-specific - Mitochondria" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 4: Non-specific - Transcription" "Cluster 69: Urothelial cells - Basic cellular functions" 5 "Nucleoplasm, Mitochondria" "HPA054091: " "unprognostic (1.68e-1)" "unprognostic (3.80e-2)" "unprognostic (1.83e-1)" "unprognostic (1.83e-2)" "unprognostic (2.43e-1)" "unprognostic (1.86e-1)" "unprognostic (7.33e-2)" "unprognostic (3.22e-2)" "unprognostic (1.10e-2)" "unprognostic (1.33e-2)" "potential prognostic favorable (4.53e-4)" "unprognostic (8.72e-2)" "potential prognostic favorable (4.02e-4)" "unprognostic (3.48e-2)" "unprognostic (7.25e-2)" "unprognostic (2.52e-2)" "unprognostic (2.14e-1)" "unprognostic (1.38e-1)" "unprognostic (3.56e-1)" "unprognostic (4.81e-2)" "unprognostic (7.14e-2)" "unprognostic (1.67e-3)" "unprognostic (3.90e-1)" "unprognostic (9.04e-2)" "unprognostic (2.82e-1)" "unprognostic (1.17e-1)" "unprognostic (3.10e-1)" "unprognostic (9.59e-2)" "unprognostic (1.01e-1)" "unprognostic (9.14e-2)" "unprognostic (1.15e-2)" BCCIP "BCCIPalpha, TOK-1" ENSG00000107949 "BRCA2 and CDKN1A interacting protein" Q9P287 10 125823546-125853695 "Essential proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038011 Approved Nucleoplasm,Cytosol NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 17: Non-specific - RNA processing" 31 Nucleoplasm Cytosol "HPA038011: " "unprognostic (2.11e-2)" "unprognostic (1.76e-2)" "unprognostic (4.11e-2)" "unprognostic (3.34e-1)" "unprognostic (7.33e-3)" "unprognostic (1.84e-1)" "unprognostic (1.86e-1)" "unprognostic (1.59e-3)" "potential prognostic unfavorable (8.06e-4)" "potential prognostic unfavorable (5.07e-5)" "potential prognostic favorable (4.07e-4)" "unprognostic (1.99e-1)" "potential prognostic unfavorable (5.65e-4)" "potential prognostic unfavorable (4.24e-5)" "unprognostic (1.27e-3)" "potential prognostic unfavorable (4.66e-5)" "unprognostic (6.45e-2)" "unprognostic (2.94e-2)" "unprognostic (6.05e-2)" "unprognostic (5.19e-2)" "unprognostic (6.35e-3)" "unprognostic (8.63e-3)" "unprognostic (9.70e-3)" "unprognostic (2.03e-3)" "unprognostic (1.14e-1)" "unprognostic (1.13e-1)" "unprognostic (4.74e-2)" "unprognostic (1.00e-1)" "unprognostic (5.28e-2)" "unprognostic (3.63e-1)" "unprognostic (3.76e-2)" BCDIN3D ENSG00000186666 "BCDIN3 domain containing RNA methyltransferase" Q7Z5W3 12 49836043-49843106 "Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "skeletal muscle: 20.4" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039911, HPA075425" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 30: White matter - Myelination" "Cluster 38: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 1 Cytosol "Nucleoplasm, Plasma membrane" "HPA039911: , HPA075425: " "unprognostic (7.77e-3)" "unprognostic (2.00e-2)" "unprognostic (3.35e-2)" "unprognostic (1.34e-2)" "unprognostic (2.25e-2)" "unprognostic (2.42e-1)" "unprognostic (3.78e-1)" "unprognostic (2.99e-1)" "unprognostic (2.67e-2)" "unprognostic (4.97e-2)" "potential prognostic favorable (6.22e-5)" "unprognostic (7.59e-3)" "unprognostic (6.70e-3)" "unprognostic (7.15e-3)" "unprognostic (7.94e-3)" "unprognostic (1.55e-1)" "unprognostic (2.07e-1)" "unprognostic (1.04e-2)" "unprognostic (3.25e-2)" "unprognostic (7.26e-2)" "unprognostic (3.32e-2)" "potential prognostic favorable (9.72e-4)" "unprognostic (1.34e-1)" "unprognostic (1.44e-1)" "unprognostic (9.68e-2)" "unprognostic (3.32e-2)" "unprognostic (1.25e-3)" "unprognostic (1.36e-1)" "unprognostic (3.14e-2)" "unprognostic (4.15e-2)" "potential prognostic favorable (5.77e-4)" BCHE "CHE1, CHE2, E1" ENSG00000114200 Butyrylcholinesterase P06276 3 165772904-165837462 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Serine esterase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "liver: 490.0" "Cell type enhanced" "Detected in many" "Bergmann glia: 60.5;Corticotrophs: 90.0;Hepatocytes: 566.3;Mesothelial cells: 232.5;Oligodendrocyte progenitor cells: 244.6;Smooth muscle cells: 173.5" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 92.9;oligodendrocyte precursor cell: 269.3" "Group enriched" "Detected in many" 5 "Glioblastoma Multiforme (TCGA): 72.4;Kidney Renal Papillary Cell Carcinoma (TCGA): 18.8;Liver Hepatocellular Carcinoma (TCGA): 41.4;Skin Cutaneous Melanoma (TCGA): 40.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Fibroblasts, Liver - Hepatocytes, Minor Salivary Gland - Fibroblasts, Pituitary gland - Corticotropes, Prostate - Smooth muscle cells, Stomach - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" HPA001560 Approved "Secreted to blood" Enzyme NA NA 3820000000 1800000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 93: Hepatocytes - Bile production & excretion" 8 "HPA001560: " "unprognostic (1.09e-1)" "unprognostic (1.10e-1)" "unprognostic (3.03e-2)" "unprognostic (5.73e-2)" "unprognostic (3.78e-2)" "unprognostic (1.61e-1)" "potential prognostic unfavorable (3.23e-5)" "unprognostic (7.08e-2)" "unprognostic (1.70e-3)" "unprognostic (2.70e-1)" "unprognostic (1.72e-1)" "unprognostic (9.56e-3)" "unprognostic (1.28e-1)" "unprognostic (7.94e-2)" "unprognostic (1.37e-1)" "unprognostic (2.07e-1)" "unprognostic (1.15e-1)" "unprognostic (1.58e-2)" "unprognostic (5.06e-2)" "unprognostic (1.14e-1)" "unprognostic (1.09e-1)" "unprognostic (7.71e-2)" "unprognostic (2.82e-2)" "unprognostic (1.60e-3)" "unprognostic (1.01e-2)" "unprognostic (6.13e-2)" "unprognostic (1.71e-2)" BCKDHA "MSU, OVD1A" ENSG00000248098 "Branched chain keto acid dehydrogenase E1 subunit alpha" P12694 19 41397808-41425002 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant, Maple syrup urine disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 8.5;Bergmann glia: 10.9;Brain excitatory neurons: 7.8;Brain inhibitory neurons: 7.4;Esophageal apical cells: 12.2;Foveolar cells: 7.5;Microglia: 7.9;Oligodendrocyte progenitor cells: 9.6;Oligodendrocytes: 9.3;Other brain neurons: 8.8;Parietal cells: 10.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Stomach - Parietal cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036640 Supported NA NA 9700 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 70: Non-specific - Protein processing" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 15: Non-specific - Protein processing" 32 "HPA036640: " "unprognostic (4.14e-2)" "unprognostic (3.03e-2)" "unprognostic (1.91e-2)" "unprognostic (7.81e-3)" "unprognostic (1.88e-1)" "unprognostic (1.97e-1)" "unprognostic (8.60e-2)" "unprognostic (1.17e-1)" "unprognostic (2.49e-3)" "unprognostic (3.19e-1)" "potential prognostic favorable (1.65e-9)" "unprognostic (2.61e-1)" "potential prognostic favorable (8.94e-6)" "unprognostic (4.94e-2)" "unprognostic (3.57e-2)" "unprognostic (1.50e-1)" "unprognostic (1.78e-1)" "unprognostic (8.71e-2)" "unprognostic (1.74e-1)" "unprognostic (9.06e-2)" "unprognostic (3.44e-3)" "unprognostic (3.25e-2)" "unprognostic (1.27e-2)" "unprognostic (1.13e-1)" "unprognostic (1.46e-1)" "unprognostic (3.30e-1)" "unprognostic (1.62e-1)" "unprognostic (8.94e-2)" "unprognostic (6.00e-2)" "unprognostic (1.13e-1)" "unprognostic (4.17e-3)" BCKDHB ENSG00000083123 "Branched chain keto acid dehydrogenase E1 subunit beta" P21953 6 80106647-80346270 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Disease variant, Maple syrup urine disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 73.2" "Cell type enhanced" "Detected in all" "Bergmann glia: 486.7;Pituitary stem cells: 429.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031580, HPA031956" Approved Supported Nucleoplasm,Nucleoli,Mitochondria Yes No "Cluster 5: Non-specific - Cell proliferation" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 55: Non-specific - Transcription" "Cluster 3: Rhabdoid - Membrane components" "Cluster 28: Astrocytes - Homeostasis & neuron support" 5 Mitochondria "Nucleoplasm, Nucleoli" "HPA031580: , HPA031956: " "potential prognostic favorable (7.56e-4)" "unprognostic (2.45e-1)" "unprognostic (2.22e-3)" "unprognostic (8.04e-2)" "unprognostic (5.99e-2)" "unprognostic (1.89e-2)" "unprognostic (1.86e-1)" "unprognostic (4.43e-2)" "unprognostic (3.08e-2)" "potential prognostic unfavorable (6.12e-4)" "potential prognostic favorable (7.45e-8)" "unprognostic (7.74e-3)" "unprognostic (3.61e-2)" "unprognostic (1.43e-2)" "unprognostic (4.88e-2)" "unprognostic (7.29e-2)" "unprognostic (3.50e-2)" "unprognostic (2.30e-1)" "unprognostic (3.08e-2)" "unprognostic (3.14e-1)" "potential prognostic unfavorable (1.59e-4)" "unprognostic (2.45e-1)" "unprognostic (1.08e-1)" "unprognostic (1.02e-1)" "potential prognostic favorable (2.29e-4)" "unprognostic (9.35e-2)" "unprognostic (1.46e-1)" "unprognostic (2.53e-2)" "unprognostic (1.43e-1)" "unprognostic (9.71e-3)" "unprognostic (1.83e-1)" BCKDK ENSG00000103507 "Branched chain keto acid dehydrogenase kinase" O14874 16 31106107-31112791 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Autism, Autism spectrum disorder, Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 120.6;Esophageal apical cells: 115.3;Extravillous trophoblasts: 92.7;Hofbauer cells: 99.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 96.0;granulocytes: 90.1;monocytes: 115.1" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017995, HPA056067" Supported Supported Mitochondria NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 70: Non-specific - Protein processing" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 8: Non-specific - Secretory pathway" 43 Mitochondria "HPA017995: , HPA056067: " "unprognostic (6.40e-2)" "unprognostic (5.36e-2)" "unprognostic (1.46e-1)" "unprognostic (1.32e-1)" "unprognostic (1.16e-1)" "unprognostic (1.23e-2)" "unprognostic (1.68e-3)" "unprognostic (1.69e-1)" "unprognostic (7.20e-2)" "unprognostic (1.31e-1)" "unprognostic (3.76e-3)" "unprognostic (6.67e-3)" "unprognostic (2.51e-2)" "unprognostic (2.80e-1)" "unprognostic (2.09e-1)" "unprognostic (1.16e-1)" "unprognostic (5.20e-3)" "unprognostic (3.28e-1)" "unprognostic (2.51e-1)" "unprognostic (1.76e-1)" "unprognostic (8.72e-2)" "unprognostic (7.82e-2)" "unprognostic (1.07e-1)" "unprognostic (1.37e-1)" "unprognostic (1.84e-1)" "unprognostic (1.99e-2)" "unprognostic (5.58e-2)" "unprognostic (2.84e-2)" "unprognostic (1.42e-1)" "unprognostic (1.03e-1)" "unprognostic (4.79e-2)" BCL10 "c-E10, CARMEN, CIPER, CLAP, mE10" ENSG00000142867 "BCL10 immune signaling adaptor" O95999 1 85265776-85276632 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Adaptive immunity, Apoptosis, Immunity, Innate immunity" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 214.1;Endometrial glandular cells: 197.8;Endometrial secretory cells: 214.2;Esophageal apical cells: 405.7;Fallopian secretory cells: 215.5;Ocular epithelial cells: 249.0;Suprabasal keratinocytes: 190.1;Urothelial cells: 223.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001944, HPA017925, HPA018953" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 12: Non-specific - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 100: Stratified epithelial cells - Barrier functions" 38 Cytosol Nucleoplasm "CAB001944: , HPA017925: , HPA018953: " "unprognostic (3.29e-2)" "unprognostic (1.66e-1)" "unprognostic (3.96e-1)" "unprognostic (7.24e-3)" "potential prognostic favorable (4.80e-5)" "unprognostic (4.68e-3)" "unprognostic (3.84e-2)" "unprognostic (1.95e-2)" "unprognostic (2.27e-2)" "unprognostic (1.10e-2)" "validated prognostic favorable (1.52e-10)" "validated prognostic favorable (8.72e-4)" "unprognostic (6.24e-2)" "potential prognostic unfavorable (3.38e-5)" "unprognostic (2.86e-2)" "unprognostic (1.24e-1)" "unprognostic (1.12e-2)" "unprognostic (5.48e-2)" "unprognostic (2.43e-1)" "unprognostic (1.39e-1)" "unprognostic (2.78e-1)" "unprognostic (1.24e-2)" "unprognostic (3.18e-2)" "unprognostic (2.04e-1)" "unprognostic (4.64e-2)" "unprognostic (2.74e-1)" "unprognostic (7.99e-2)" "unprognostic (1.03e-1)" "unprognostic (1.87e-1)" "unprognostic (3.59e-2)" "unprognostic (4.23e-1)" BCL11A "BCL11A-L, BCL11A-S, BCL11A-XL, CTIP1, EVI9, HBFQTL5, SMARCM1, ZNF856" ENSG00000119866 "BAF chromatin remodeling complex subunit BCL11A" Q9H165 2 60450520-60554467 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 49.4;lymphoid tissue: 38.2;skin 1: 44.7" "Cell type enhanced" "Detected in many" "B-cells: 441.3;cDC: 181.3;Hematopoietic stem cells: 300.8;Medullary thymic epithelial cells: 187.2;pDCs: 879.4;Thymocytes: 210.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "memory B-cell: 313.9;naive B-cell: 417.5;plasmacytoid DC: 902.0" "Group enriched" "Detected in all" 15 "B-cells: 417.5;dendritic cells: 902.0" "Cancer enhanced" "Detected in many" "Leukemia: 31.3;lymphoma: 37.1" "Adipose visceral - T-cells, Heart muscle - Cardiomyocytes, Pituitary gland - Thyrotropes, Skin - Keratinocyte (other), Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basal ganglia: 60.5;cerebral cortex: 88.7;hippocampal formation: 77.9;olfactory bulb: 74.7" "CAB014891, HPA029003, HPA075941" Enhanced Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 30 Nucleoplasm "Nuclear bodies" "CAB014891: , HPA029003: , HPA075941: " "unprognostic (1.00e-1)" "unprognostic (4.11e-2)" "unprognostic (2.89e-2)" "unprognostic (3.38e-1)" "unprognostic (5.84e-2)" "unprognostic (1.91e-1)" "unprognostic (2.68e-1)" "unprognostic (2.17e-1)" "unprognostic (4.54e-3)" "unprognostic (5.53e-3)" "unprognostic (1.34e-1)" "unprognostic (2.10e-1)" "unprognostic (8.63e-3)" "unprognostic (1.81e-2)" "unprognostic (2.53e-2)" "unprognostic (5.80e-3)" "unprognostic (5.85e-2)" "unprognostic (1.39e-1)" "unprognostic (2.16e-2)" "unprognostic (1.75e-3)" "unprognostic (1.51e-3)" "unprognostic (2.57e-2)" "unprognostic (3.67e-1)" "unprognostic (3.41e-1)" "unprognostic (7.24e-2)" "unprognostic (7.00e-2)" "unprognostic (1.08e-1)" "unprognostic (9.66e-3)" "unprognostic (3.27e-2)" BCL11B "CTIP-2, CTIP2, hRIT1-alpha, SMARCM2, ZNF856B" ENSG00000127152 "BAF chromatin remodeling complex subunit BCL11B" Q9C0K0 14 99169287-99272197 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Repressor "Cancer-related genes, Disease variant, Intellectual disability, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 12.4;lymphoid tissue: 34.1;skin 1: 14.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 132.6;Brain excitatory neurons: 91.1;Brain inhibitory neurons: 200.9;NK-cells: 151.1;Suprabasal keratinocytes: 113.1;T-cells: 674.6;Thymocytes: 246.5" "Cell type enhanced" "Detected in many" "leukocyte: 662.6" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 5 "amygdala: 21.7;basal ganglia: 49.0;cerebral cortex: 40.1;hippocampal formation: 43.7;white matter: 13.2" "Group enriched" "Detected in many" 8 "gdT-cell: 2.0;MAIT T-cell: 1.8;memory CD4 T-cell: 2.8;memory CD8 T-cell: 2.4;naive CD4 T-cell: 4.6;naive CD8 T-cell: 3.1;T-reg: 2.1" "Lineage enriched" "Detected in single" 14 "T-cells: 4.6" "Group enriched" "Detected in many" 7 "Bone cancer: 16.7;Leukemia: 7.0" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Minor Salivary Gland - Minor salivary gland basal cells, Pancreas - T-cells, Prostate - T-cells, Skin - Keratinocyte (other), Spleen - T-cells, Stomach - T-cells, Testis - Spermatogonia, Thyroid gland - T-cells" "Region enhanced" "Detected in many" "basal ganglia: 64.4" "Region enhanced" "Detected in many" "basal ganglia: 41.9" HPA049117 Enhanced Supported Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 51: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" 25 Nucleoplasm "Nucleoli fibrillar center" "HPA049117: " "unprognostic (2.16e-2)" "potential prognostic favorable (7.66e-5)" "unprognostic (3.75e-2)" "unprognostic (7.73e-2)" "unprognostic (1.94e-1)" "unprognostic (1.67e-1)" "potential prognostic favorable (6.49e-4)" "unprognostic (7.15e-2)" "unprognostic (2.51e-1)" "unprognostic (1.36e-1)" "unprognostic (5.52e-3)" "unprognostic (2.41e-1)" "unprognostic (3.93e-2)" "unprognostic (6.60e-2)" "unprognostic (1.75e-1)" "unprognostic (3.47e-1)" "unprognostic (1.50e-1)" "unprognostic (5.38e-2)" "unprognostic (3.08e-1)" "unprognostic (1.79e-3)" "unprognostic (1.52e-1)" BCL2 "Bcl-2, PPP1R50" ENSG00000171791 "BCL2 apoptosis regulator" P10415 18 63123346-63320128 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Autophagy" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 1139.2;B-cells: 739.7;Epididymal clear cells: 841.0;Melanocytes: 1004.4;Pituitary stem cells: 1810.5;Respiratory ionocytes: 901.7;Salivary ionocytes: 900.0;Schwann cells: 869.7;T-cells: 738.2" "Cell type enhanced" "Detected in all" "leukocyte: 1345.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 18 "B-cells: 5.4;T-cells: 8.6" "Cancer enhanced" "Detected in all" "lymphoma: 53.5;Myeloma: 68.5" "Adipose subcutaneous - Adipocytes (Subcutaneous), Colon - Enteric glia cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Skeletal muscle - Skeletal myocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000003, CAB080071, CAB080083" Enhanced Enhanced Mitochondria NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 9: T-cells - Adaptive immunity: Regulation" 98 Mitochondria "CAB000003: , CAB080071: , CAB080083: " "unprognostic (1.23e-2)" "unprognostic (1.21e-2)" "unprognostic (1.62e-3)" "unprognostic (1.22e-2)" "unprognostic (1.34e-1)" "unprognostic (8.97e-2)" "unprognostic (2.00e-1)" "unprognostic (3.53e-1)" "unprognostic (2.88e-2)" "unprognostic (1.61e-1)" "validated prognostic favorable (1.60e-11)" "validated prognostic favorable (2.68e-4)" "unprognostic (1.34e-1)" "unprognostic (1.56e-2)" "potential prognostic favorable (1.56e-4)" "unprognostic (1.48e-1)" "unprognostic (2.68e-2)" "unprognostic (6.02e-3)" "unprognostic (4.98e-1)" "unprognostic (4.94e-2)" "unprognostic (9.81e-2)" "unprognostic (3.07e-1)" "unprognostic (2.03e-1)" "unprognostic (8.56e-2)" "unprognostic (1.72e-1)" "unprognostic (2.63e-1)" "unprognostic (2.25e-1)" "unprognostic (1.38e-2)" "unprognostic (4.60e-3)" "unprognostic (1.79e-1)" BCL2A1 "ACC-1, ACC-2, ACC1, ACC2, BCL2L5, BFL1, GRS, HBPA1" ENSG00000140379 "BCL2 related protein A1" Q16548 15 79960892-79971196 "Cancer-related genes, Predicted intracellular proteins" Apoptosis "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "bone marrow: 583.4" "Cell type enriched" "Detected in many" 4 "Neutrophils: 4588.1" "Cell type enriched" "Detected in some" 8 "leukocyte: 37.5" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 100.3" "Group enriched" "Detected in all" 5 "cerebral cortex: 71.9;pons: 19.9" "Group enriched" "Detected in all" 5 "eosinophil: 293.8;intermediate monocyte: 197.3;neutrophil: 565.4;non-classical monocyte: 384.0" "Group enriched" "Detected in all" 7 "granulocytes: 565.4;monocytes: 384.0" "Group enriched" "Detected in many" 6 "lymphoma: 128.4;skin cancer: 99.8" "Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Lung - Neutrophils_2, Skeletal muscle - Neutrophils, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 15: Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 55: Lymphoma - Immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 14 "unprognostic (1.41e-1)" "unprognostic (2.05e-2)" "unprognostic (1.54e-1)" "unprognostic (4.50e-1)" "unprognostic (2.68e-1)" "unprognostic (1.01e-1)" "potential prognostic unfavorable (4.20e-4)" "unprognostic (1.23e-1)" "unprognostic (1.17e-1)" "unprognostic (3.60e-1)" "unprognostic (2.60e-3)" "unprognostic (1.88e-1)" "unprognostic (1.74e-1)" "unprognostic (1.74e-1)" "unprognostic (3.00e-1)" "unprognostic (2.53e-1)" "unprognostic (2.93e-3)" "unprognostic (1.46e-1)" "unprognostic (2.23e-1)" "unprognostic (6.79e-2)" "unprognostic (1.93e-1)" "unprognostic (2.06e-2)" "unprognostic (4.48e-2)" "unprognostic (1.70e-1)" "unprognostic (2.09e-3)" "unprognostic (1.04e-1)" "unprognostic (3.89e-1)" "unprognostic (1.02e-1)" "unprognostic (5.09e-2)" "unprognostic (2.39e-1)" "unprognostic (3.12e-1)" BCL2L1 "Bcl-X, bcl-xL, bcl-xS, BCL2L, BCLX, PPP1R52" ENSG00000171552 "BCL2 like 1" Q07817 20 31664452-31723989 "Cancer-related genes, Essential proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Apoptosis, Endocytosis" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 389.3;Esophageal apical cells: 415.4;Platelets: 420.3" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 299.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035734, CAB072801" Approved Approved "Nucleoli fibrillar center,Mitochondria,Acrosome" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 51: Secretory epithelial cells - Mixed function" 83 Mitochondria "Nucleoli fibrillar center, Acrosome" "CAB072801: , HPA035734: " "unprognostic (1.35e-2)" "unprognostic (3.28e-1)" "unprognostic (2.94e-2)" "unprognostic (1.07e-2)" "unprognostic (2.66e-1)" "unprognostic (3.79e-2)" "unprognostic (1.60e-1)" "unprognostic (7.25e-3)" "unprognostic (1.85e-1)" "unprognostic (2.47e-1)" "potential prognostic favorable (4.09e-6)" "unprognostic (1.52e-2)" "unprognostic (2.58e-3)" "unprognostic (2.83e-2)" "unprognostic (6.21e-2)" "unprognostic (3.06e-3)" "unprognostic (4.37e-2)" "unprognostic (2.23e-2)" "unprognostic (9.20e-2)" "unprognostic (4.57e-2)" "unprognostic (2.34e-2)" "potential prognostic unfavorable (3.57e-4)" "unprognostic (6.21e-2)" "unprognostic (4.35e-2)" "unprognostic (6.13e-2)" "unprognostic (5.68e-3)" "unprognostic (1.38e-1)" "unprognostic (1.28e-1)" "unprognostic (1.58e-1)" "unprognostic (1.38e-2)" "unprognostic (2.29e-1)" BCL2L10 "BCL-B, Boo, Diva" ENSG00000137875 "BCL2 like 10" Q9HD36 15 52109263-52112775 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "liver: 9.2;skin 1: 6.5" "Cell type enriched" "Detected in some" 12 "Oocytes: 285.5" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 10.2" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 1.4" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in some" "Skin - Keratinocyte (other)" "Not detected" "Not detected" HPA042222 Enhanced NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 55: Lymphoma - Immune response" "Cluster 41: Oocytes - Oogenesis" 18 "HPA042222: " "unprognostic (4.93e-3)" "unprognostic (3.53e-2)" "unprognostic (2.38e-1)" "unprognostic (1.10e-1)" "unprognostic (2.52e-2)" "unprognostic (8.48e-2)" "unprognostic (4.57e-2)" "potential prognostic favorable (6.82e-4)" "unprognostic (2.06e-3)" "unprognostic (1.26e-2)" "unprognostic (1.17e-1)" "unprognostic (1.07e-2)" "potential prognostic unfavorable (4.56e-4)" "unprognostic (1.51e-1)" "unprognostic (5.33e-2)" "unprognostic (2.36e-1)" "unprognostic (2.69e-1)" "unprognostic (3.36e-1)" "unprognostic (3.96e-1)" "unprognostic (5.29e-2)" "unprognostic (1.93e-1)" "unprognostic (1.97e-1)" BCL2L11 "BIM, BimEL, BimL, BimS, BOD" ENSG00000153094 "BCL2 like 11" O43521 2 111119378-111168445 "Predicted intracellular proteins, Transporters" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 155.9;Plasma cells: 364.2" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 43.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026332, CAB079899" Approved Supported Mitochondria NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 11: White matter - Signal transduction" "Cluster 55: Lymphoma - Immune response" "Cluster 44: Plasma cells - Antibody production & secretion" 44 Mitochondria "CAB026332: , CAB079899: " "unprognostic (1.89e-1)" "unprognostic (8.36e-2)" "unprognostic (3.67e-1)" "unprognostic (1.71e-1)" "unprognostic (6.45e-2)" "unprognostic (2.54e-2)" "unprognostic (4.19e-2)" "unprognostic (1.14e-1)" "unprognostic (3.74e-3)" "unprognostic (2.26e-2)" "unprognostic (2.70e-3)" "unprognostic (4.03e-2)" "unprognostic (7.86e-3)" "unprognostic (1.66e-1)" "unprognostic (5.62e-2)" "unprognostic (6.18e-2)" "unprognostic (2.60e-1)" "unprognostic (3.98e-2)" "unprognostic (3.21e-1)" "unprognostic (1.97e-3)" "potential prognostic unfavorable (5.77e-4)" "unprognostic (3.85e-2)" "unprognostic (2.84e-2)" "unprognostic (1.24e-1)" "unprognostic (5.88e-2)" "unprognostic (1.80e-3)" "unprognostic (3.19e-2)" "unprognostic (1.82e-2)" "unprognostic (1.73e-1)" "unprognostic (2.98e-3)" "unprognostic (3.24e-1)" BCL2L12 ENSG00000126453 "BCL2 like 12" Q9HB09 19 49665142-49673916 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 66.8;Cytotrophoblasts: 84.6;Epicardial cells: 102.3;Extravillous trophoblasts: 153.5;Migrating cytotrophoblasts: 96.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" HPA020856 Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 4: Non-specific - Transcription" "Cluster 27: Non-specific - Cell proliferation" 15 Vesicles "Plasma membrane" "HPA020856: " "unprognostic (1.08e-1)" "unprognostic (9.36e-2)" "unprognostic (4.10e-1)" "unprognostic (8.17e-2)" "unprognostic (9.63e-2)" "unprognostic (1.81e-1)" "unprognostic (5.17e-2)" "unprognostic (1.06e-1)" "unprognostic (1.48e-1)" "unprognostic (2.06e-2)" "validated prognostic unfavorable (5.91e-8)" "validated prognostic unfavorable (1.71e-7)" "unprognostic (3.37e-3)" "potential prognostic unfavorable (2.65e-5)" "unprognostic (4.32e-3)" "unprognostic (2.21e-3)" "unprognostic (1.50e-2)" "unprognostic (9.21e-2)" "unprognostic (4.30e-2)" "unprognostic (2.08e-1)" "unprognostic (5.64e-2)" "unprognostic (2.71e-3)" "unprognostic (1.57e-1)" "unprognostic (7.00e-3)" "unprognostic (1.12e-1)" "unprognostic (7.12e-2)" "unprognostic (1.31e-2)" "unprognostic (7.83e-2)" "unprognostic (1.08e-1)" "unprognostic (1.21e-1)" "unprognostic (1.22e-1)" BCL2L13 "BCL-RAMBO, MIL1" ENSG00000099968 "BCL2 like 13" Q9BXK5 22 17628855-17730855 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Myonuclei: 305.3;Ocular epithelial cells: 471.4;Retinal bipolar cells: 330.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002052, HPA030994, HPA050377" Uncertain Enhanced Mitochondria NA NA 37000 "Cluster 33: Non-specific - ATP binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 66: Non-specific - Mitochondria" "Cluster 100: Stratified epithelial cells - Barrier functions" 51 Mitochondria "CAB002052: , HPA030994: , HPA050377: " "unprognostic (2.08e-1)" "unprognostic (7.49e-2)" "unprognostic (1.56e-2)" "unprognostic (3.09e-2)" "unprognostic (1.02e-2)" "unprognostic (1.30e-1)" "unprognostic (3.06e-2)" "unprognostic (8.68e-3)" "unprognostic (3.52e-1)" "unprognostic (1.74e-2)" "potential prognostic favorable (1.51e-6)" "unprognostic (1.35e-3)" "unprognostic (8.40e-2)" "unprognostic (8.35e-2)" "unprognostic (1.10e-1)" "unprognostic (6.74e-2)" "unprognostic (1.73e-1)" "unprognostic (1.01e-1)" "unprognostic (3.11e-1)" "unprognostic (2.02e-1)" "unprognostic (1.48e-1)" "unprognostic (1.98e-3)" "unprognostic (5.01e-2)" "unprognostic (2.85e-1)" "unprognostic (2.48e-2)" "unprognostic (2.89e-2)" "unprognostic (1.15e-1)" "unprognostic (3.24e-1)" "unprognostic (1.67e-1)" "unprognostic (3.13e-2)" "unprognostic (1.83e-1)" BCL2L14 "BCL-G, BCLG" ENSG00000121380 "BCL2 like 14" Q9BZR8 12 12049844-12211084 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 14.5;stomach 1: 8.8;testis: 29.6" "Cell type enhanced" "Detected in some" "Astrocytes: 38.5;Bergmann glia: 38.5;Brain excitatory neurons: 29.9;Brain inhibitory neurons: 26.4;Distal convoluted tubule cells: 33.3;Early spermatids: 85.7;Ependymal cells: 38.4;Late primary spermatocytes: 40.4;Late spermatids: 275.6;Loop of henle epithelial cells: 40.2;Oligodendrocyte progenitor cells: 44.2;Oligodendrocytes: 47.9;Other brain neurons: 31.7;Papillary tip epithelial cells: 37.0;Renal collecting duct intercalated cells: 26.9;Renal collecting duct principal cells: 27.3" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Colon Adenocarcinoma (TCGA): 10.6;Pancreatic Adenocarcinoma (TCGA): 4.0;Rectum Adenocarcinoma (TCGA): 10.4;Stomach Adenocarcinoma (TCGA): 7.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 18.8;colorectal cancer: 6.4" "Breast - Breast glandular cells (progenitors), Colon - Colon enterocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA040665, HPA059846" Enhanced Supported Vesicles,Cytosol NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 21: Testis - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 28: Astrocytes - Homeostasis & neuron support" 33 Cytosol Vesicles "HPA040665: , HPA059846: " "unprognostic (4.59e-3)" "potential prognostic favorable (4.93e-4)" "unprognostic (6.41e-3)" "potential prognostic favorable (3.99e-4)" "unprognostic (2.75e-1)" "unprognostic (4.15e-2)" "unprognostic (1.84e-2)" "unprognostic (1.87e-1)" "unprognostic (3.59e-3)" "unprognostic (2.32e-1)" "unprognostic (2.97e-2)" "potential prognostic favorable (3.22e-4)" "unprognostic (1.36e-3)" "unprognostic (7.13e-3)" "unprognostic (3.18e-2)" "unprognostic (4.56e-2)" "potential prognostic favorable (6.83e-6)" "unprognostic (1.77e-2)" "unprognostic (4.61e-2)" "unprognostic (9.08e-2)" BCL2L15 "Bfk, C1orf178, FLJ22588" ENSG00000188761 "BCL2 like 15" Q5TBC7 1 113876816-113887581 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 12.5;intestine: 40.7;stomach 1: 17.4" "Cell type enhanced" "Detected in many" "Colonocytes: 92.1;Conjunctival goblet cells: 47.6;Endometrial secretory cells: 61.3;Enteric stem cells: 38.5;Enteric transient amplifying cells: 66.6;Enterocytes: 144.5;Foveolar cells: 48.4;Gastric chief cells: 43.7;Gastric progenitor cells: 123.0;Goblet cells: 43.3;Neutrophil progenitors: 75.0" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 25.1;Pancreatic Adenocarcinoma (TCGA): 23.5;Rectum Adenocarcinoma (TCGA): 23.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Bile duct cancer: 13.6;colorectal cancer: 16.7;Gastric cancer: 6.7;pancreatic cancer: 4.8" "Colon - Colon enterocytes, Testis - Early spermatids" "Region enriched" "Detected in some" 32 "cerebellum: 32.9" "Low region specificity" "Detected in all" "HPA029732, HPA029733" Enhanced NA NA "Cluster 77: Intestine - Digestion" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 1: Enterocytes - Absorption and Digestion" 7 "HPA029732: , HPA029733: " "unprognostic (1.61e-1)" "unprognostic (3.77e-2)" "unprognostic (1.43e-3)" "unprognostic (5.77e-2)" "unprognostic (6.07e-2)" "unprognostic (1.16e-2)" "unprognostic (1.37e-3)" "unprognostic (1.20e-1)" "unprognostic (7.39e-2)" "unprognostic (4.41e-1)" "unprognostic (4.14e-2)" "unprognostic (2.04e-2)" "unprognostic (3.33e-3)" "unprognostic (1.26e-1)" "unprognostic (5.04e-2)" "unprognostic (2.48e-3)" "unprognostic (1.54e-2)" "unprognostic (1.62e-1)" BCL2L2 "BCL-W, KIAA0271, PPP1R51" ENSG00000129473 "BCL2 like 2" Q92843 14 23298790-23311751 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Apoptosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Cardiomyocytes: 354.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB040539, HPA048740" Approved Uncertain Nucleoplasm NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 64 Nucleoplasm "CAB040539: , HPA048740: " "unprognostic (4.47e-2)" "unprognostic (2.07e-2)" "unprognostic (2.50e-1)" "unprognostic (4.89e-2)" "unprognostic (1.12e-1)" "unprognostic (3.82e-1)" "unprognostic (3.63e-1)" "unprognostic (2.17e-1)" "unprognostic (2.79e-1)" "unprognostic (3.67e-2)" "potential prognostic favorable (4.48e-6)" "unprognostic (3.47e-3)" "unprognostic (6.29e-2)" "potential prognostic unfavorable (2.42e-4)" "unprognostic (7.22e-2)" "unprognostic (5.02e-2)" "unprognostic (3.10e-1)" "unprognostic (3.90e-1)" "unprognostic (1.51e-1)" "unprognostic (1.30e-3)" "unprognostic (3.37e-1)" "unprognostic (2.41e-3)" "unprognostic (1.53e-1)" "unprognostic (1.58e-1)" "unprognostic (1.54e-1)" "unprognostic (2.51e-2)" "unprognostic (4.07e-2)" "unprognostic (1.71e-1)" "unprognostic (2.50e-2)" "unprognostic (4.32e-2)" "unprognostic (1.64e-1)" BCL2L2-PABPN1 ENSG00000258643 "BCL2L2-PABPN1 readthrough" Q92843 14 23306833-23326175 "Cancer-related genes, Predicted intracellular proteins, Transporters" Apoptosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 44.5;Sertoli cells: 75.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.9" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "HPA000637, HPA048740" Approved Uncertain "Nucleoplasm,Nuclear speckles" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 14: Neurons - Synaptic function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 48 Nucleoplasm "Nuclear speckles" "HPA000637: , HPA048740: " "unprognostic (5.52e-3)" "unprognostic (2.02e-2)" "unprognostic (4.56e-2)" "unprognostic (1.37e-1)" "unprognostic (2.13e-1)" "unprognostic (3.06e-2)" "unprognostic (2.38e-2)" "unprognostic (1.74e-3)" "unprognostic (4.92e-2)" "unprognostic (5.26e-2)" "unprognostic (7.51e-2)" "unprognostic (2.11e-1)" "unprognostic (2.00e-3)" "unprognostic (8.23e-2)" "unprognostic (3.29e-1)" "unprognostic (1.22e-1)" "unprognostic (1.42e-1)" "unprognostic (1.33e-3)" "unprognostic (4.63e-2)" "unprognostic (3.46e-1)" "unprognostic (3.54e-2)" "unprognostic (1.32e-1)" "unprognostic (1.77e-2)" "unprognostic (1.35e-1)" "unprognostic (7.84e-2)" "unprognostic (3.27e-2)" "unprognostic (9.71e-2)" "unprognostic (9.84e-3)" "unprognostic (9.94e-2)" BCL3 "BCL4, D19S37" ENSG00000069399 "BCL3 transcription coactivator" P20749 19 44747705-44760044 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Activator "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 168.5" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 163.4;Breast secretory cells: 131.1;Neutrophils: 368.1" "Cell type enhanced" "Detected in many" "endothelial cell: 13.5;leukocyte: 9.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "eosinophil: 5.5;neutrophil: 19.8" "Lineage enriched" "Detected in all" 6 "granulocytes: 19.8" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002051, HPA047514" Approved Supported "Nucleoplasm,Vesicles,Midbody,Primary cilium,Basal body,Cytosol" Yes No "Cluster 21: Neutrophils - Unknown function" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 12: Non-specific - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 25 Nucleoplasm "Vesicles, Midbody, Primary cilium, Basal body, Cytosol" "CAB002051: , HPA047514: " "unprognostic (1.01e-1)" "unprognostic (2.29e-3)" "unprognostic (1.66e-2)" "unprognostic (2.81e-1)" "unprognostic (4.12e-3)" "unprognostic (1.85e-1)" "unprognostic (1.10e-3)" "potential prognostic unfavorable (2.47e-4)" "unprognostic (2.42e-2)" "unprognostic (3.71e-2)" "potential prognostic unfavorable (2.13e-6)" "unprognostic (2.65e-2)" "unprognostic (5.10e-2)" "unprognostic (1.67e-3)" "unprognostic (2.57e-2)" "unprognostic (6.02e-2)" "unprognostic (4.67e-3)" "unprognostic (7.25e-2)" "unprognostic (1.57e-1)" "unprognostic (1.34e-2)" "unprognostic (6.66e-2)" "unprognostic (9.51e-2)" "unprognostic (5.90e-2)" "unprognostic (3.97e-1)" "unprognostic (7.91e-2)" "unprognostic (6.02e-2)" "unprognostic (1.14e-1)" "unprognostic (9.89e-2)" "unprognostic (4.15e-2)" "unprognostic (5.28e-3)" "unprognostic (6.86e-2)" BCL6 "BCL5, BCL6A, LAZ3, ZBTB27, ZNF51" ENSG00000113916 "BCL6 transcription repressor" P41182 3 187721377-187745725 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Immunity, Inflammatory response, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 527.7" "Cell type enriched" "Detected in many" 5 "Neutrophils: 2731.6" "Cell type enhanced" "Detected in many" "astrocyte: 355.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "neutrophil: 270.1;non-classical monocyte: 77.1" "Group enriched" "Detected in all" 7 "granulocytes: 270.1;monocytes: 77.1" "Cancer enriched" "Detected in all" 4 "lymphoma: 119.0" "Colon - Neutrophils, Minor Salivary Gland - Minor salivary glandular cells, Spleen - Neutrophils_2, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000307, HPA004899, HPA050645" Enhanced Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 81 Nucleoplasm "Golgi apparatus" "CAB000307: , HPA004899: , HPA050645: " "unprognostic (1.80e-2)" "unprognostic (4.09e-3)" "unprognostic (2.47e-3)" "unprognostic (2.19e-1)" "unprognostic (1.31e-1)" "unprognostic (8.33e-2)" "unprognostic (3.49e-1)" "unprognostic (2.07e-2)" "unprognostic (3.50e-2)" "unprognostic (4.60e-3)" "unprognostic (1.01e-1)" "unprognostic (7.52e-2)" "unprognostic (2.72e-1)" "unprognostic (6.98e-2)" "unprognostic (1.38e-1)" "unprognostic (1.98e-1)" "unprognostic (2.20e-2)" "unprognostic (5.56e-2)" "unprognostic (5.12e-3)" "unprognostic (1.37e-2)" "unprognostic (3.27e-1)" "unprognostic (3.23e-3)" "unprognostic (3.87e-2)" "unprognostic (3.12e-1)" "unprognostic (1.48e-2)" "unprognostic (6.97e-2)" "unprognostic (1.26e-1)" "unprognostic (6.72e-2)" "unprognostic (7.44e-2)" "unprognostic (4.11e-2)" "unprognostic (3.03e-2)" BCL6B "BAZF, ZBTB28, ZNF62" ENSG00000161940 "BCL6B transcription repressor" Q8N143 17 7023050-7030290 "Predicted intracellular proteins, Transcription factors" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 12 "Lymphatic endothelial cells: 28.9;Vascular endothelial cells: 39.9" "Cell type enriched" "Detected in some" 23 "endothelial cell: 24.6" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 26.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 2.3;ovarian cancer: 3.2" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Prostate - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA059147, HPA075112" Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 2 Nucleoplasm "Vesicles, Plasma membrane" "HPA059147: , HPA075112: " "unprognostic (8.41e-2)" "unprognostic (1.63e-2)" "unprognostic (1.01e-2)" "unprognostic (6.91e-2)" "unprognostic (2.15e-3)" "unprognostic (1.12e-1)" "unprognostic (1.25e-1)" "unprognostic (5.68e-1)" "potential prognostic favorable (9.41e-4)" "unprognostic (2.82e-1)" "validated prognostic favorable (1.84e-5)" "validated prognostic favorable (3.36e-4)" "potential prognostic unfavorable (1.35e-4)" "unprognostic (4.08e-2)" "unprognostic (4.82e-3)" "unprognostic (1.56e-1)" "unprognostic (1.60e-2)" "unprognostic (4.56e-2)" "unprognostic (1.32e-1)" "unprognostic (2.26e-1)" "unprognostic (2.69e-1)" "unprognostic (6.78e-2)" "unprognostic (9.11e-2)" "unprognostic (1.22e-1)" "unprognostic (1.60e-2)" "unprognostic (4.58e-1)" "unprognostic (5.12e-3)" "unprognostic (2.55e-2)" "unprognostic (2.81e-1)" "unprognostic (1.37e-2)" "unprognostic (2.11e-1)" BCL7A "BCL7, SMARCJ1" ENSG00000110987 "BAF chromatin remodeling complex subunit BCL7A" Q4VC05 12 122019422-122062044 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 1.0;naive B-cell: 2.1;plasmacytoid DC: 2.8" "Group enriched" "Detected in many" 14 "B-cells: 2.1;dendritic cells: 2.8" "Cancer enhanced" "Detected in all" "lymphoma: 45.8" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019762 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 27: Cerebellum - Synaptic function" "Cluster 53: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 24 "Nucleoplasm, Vesicles" "HPA019762: " "unprognostic (6.64e-2)" "unprognostic (1.22e-1)" "unprognostic (4.05e-2)" "unprognostic (2.68e-1)" "unprognostic (1.12e-2)" "unprognostic (2.14e-2)" "unprognostic (1.16e-1)" "potential prognostic favorable (4.98e-4)" "unprognostic (1.25e-1)" "unprognostic (5.13e-2)" "potential prognostic favorable (8.90e-5)" "unprognostic (1.24e-1)" "unprognostic (1.87e-2)" "unprognostic (2.37e-3)" "unprognostic (1.63e-1)" "unprognostic (2.50e-1)" "unprognostic (1.67e-1)" "unprognostic (6.95e-2)" "unprognostic (1.78e-3)" "unprognostic (2.28e-2)" "potential prognostic unfavorable (2.29e-5)" "unprognostic (1.93e-1)" "unprognostic (3.08e-1)" "unprognostic (1.75e-1)" "unprognostic (2.82e-1)" "unprognostic (6.87e-2)" "unprognostic (1.28e-2)" "unprognostic (3.95e-2)" "unprognostic (3.38e-2)" "unprognostic (7.15e-2)" "unprognostic (1.30e-1)" BCL7B SMARCJ2 ENSG00000106635 "BAF chromatin remodeling complex subunit BCL7B" Q9BQE9 7 73536356-73557690 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Differentiation, Wnt signaling pathway" "Allergen, Williams-Beuren syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Megakaryocytes: 148.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049943, HPA058069" Approved Approved Nucleoplasm NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 38: Sub-cortical - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 41 Nucleoplasm "HPA049943: , HPA058069: " "unprognostic (2.00e-2)" "unprognostic (2.33e-2)" "unprognostic (1.02e-1)" "unprognostic (2.66e-2)" "unprognostic (5.70e-2)" "unprognostic (1.27e-1)" "unprognostic (2.46e-3)" "potential prognostic unfavorable (1.41e-5)" "unprognostic (3.71e-2)" "unprognostic (4.51e-2)" "potential prognostic favorable (1.02e-6)" "unprognostic (7.96e-2)" "unprognostic (1.50e-1)" "unprognostic (7.03e-3)" "unprognostic (1.50e-2)" "unprognostic (5.28e-2)" "unprognostic (2.03e-1)" "unprognostic (1.14e-2)" "unprognostic (1.09e-1)" "unprognostic (2.87e-1)" "unprognostic (3.02e-2)" "unprognostic (2.81e-1)" "unprognostic (2.77e-1)" "unprognostic (1.96e-1)" "unprognostic (9.25e-2)" "unprognostic (7.62e-2)" "unprognostic (2.30e-1)" "unprognostic (9.34e-2)" "unprognostic (1.78e-1)" "unprognostic (2.63e-1)" "unprognostic (7.93e-3)" BCL7C SMARCJ3 ENSG00000099385 "BAF chromatin remodeling complex subunit BCL7C" Q8WUZ0 16 30833626-30894302 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Colon - Enteric glia cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018676, HPA052654" Uncertain Approved Nucleoplasm NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 74: Non-specific - Signal transduction" "Cluster 46: Brainstem - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 37 Nucleoplasm "HPA018676: , HPA052654: " "unprognostic (7.51e-2)" "unprognostic (4.46e-2)" "unprognostic (9.17e-2)" "unprognostic (2.58e-1)" "unprognostic (1.20e-1)" "unprognostic (2.65e-3)" "unprognostic (1.36e-1)" "unprognostic (2.09e-1)" "unprognostic (3.01e-1)" "unprognostic (2.57e-1)" "unprognostic (1.21e-2)" "unprognostic (2.28e-1)" "unprognostic (1.77e-1)" "unprognostic (1.11e-3)" "potential prognostic unfavorable (9.61e-4)" "unprognostic (7.17e-2)" "unprognostic (2.08e-2)" "unprognostic (2.99e-2)" "unprognostic (4.27e-1)" "unprognostic (2.73e-2)" "unprognostic (1.18e-1)" "unprognostic (2.30e-1)" "unprognostic (1.78e-1)" "unprognostic (2.75e-2)" "unprognostic (1.43e-1)" "unprognostic (3.38e-2)" "unprognostic (9.32e-2)" "unprognostic (3.59e-1)" "unprognostic (1.71e-1)" "unprognostic (1.15e-1)" "unprognostic (1.74e-1)" BCL9 ENSG00000116128 "BCL9 transcription coactivator" O00512 1 147541501-147626216 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Wnt signaling pathway" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 90.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020274 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" No No "Cluster 43: Non-specific - Transcription & Translation" "Cluster 61: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 45: Non-specific - Nuclear processes" "Cluster 51: Secretory epithelial cells - Mixed function" 16 "Nucleoplasm, Nuclear bodies" Cytosol "HPA020274: " "unprognostic (1.90e-3)" "unprognostic (7.47e-2)" "unprognostic (2.83e-2)" "unprognostic (2.27e-3)" "unprognostic (2.30e-1)" "unprognostic (1.50e-1)" "unprognostic (2.61e-1)" "unprognostic (6.73e-2)" "unprognostic (2.36e-1)" "unprognostic (2.60e-1)" "potential prognostic favorable (3.61e-4)" "unprognostic (5.00e-2)" "unprognostic (6.70e-3)" "unprognostic (1.39e-3)" "unprognostic (1.36e-1)" "unprognostic (1.06e-2)" "unprognostic (3.60e-2)" "unprognostic (1.01e-1)" "unprognostic (4.82e-2)" "unprognostic (3.69e-2)" "unprognostic (4.94e-2)" "unprognostic (2.79e-2)" "unprognostic (8.41e-2)" "unprognostic (1.48e-1)" "unprognostic (1.76e-2)" "unprognostic (2.13e-1)" "unprognostic (2.75e-2)" "unprognostic (2.52e-1)" "unprognostic (1.17e-1)" "unprognostic (8.54e-2)" "unprognostic (5.32e-2)" BCL9L "B9L, Bcl9-2, DLNB11" ENSG00000186174 "BCL9 like" Q86UU0 11 118893875-118925926 "Cancer-related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 179.5;Endometrial glandular cells: 87.0;Endometrial secretory cells: 102.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049370, HPA053421" Uncertain Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 55: Breast - Lactation" "Cluster 15: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 9: T-cells - Adaptive immunity: Regulation" 3 Nucleoplasm "Nucleoli fibrillar center" "HPA049370: , HPA053421: " "unprognostic (1.05e-2)" "unprognostic (1.93e-2)" "unprognostic (4.75e-2)" "unprognostic (1.48e-3)" "unprognostic (3.03e-1)" "unprognostic (1.10e-1)" "unprognostic (2.31e-1)" "unprognostic (6.62e-2)" "unprognostic (1.49e-1)" "unprognostic (8.08e-2)" "unprognostic (1.15e-3)" "unprognostic (3.67e-2)" "unprognostic (1.72e-1)" "unprognostic (1.76e-2)" "unprognostic (7.14e-2)" "unprognostic (4.60e-3)" "unprognostic (5.20e-3)" "unprognostic (1.23e-2)" "unprognostic (2.75e-1)" "unprognostic (3.10e-2)" "unprognostic (4.94e-2)" "unprognostic (3.44e-3)" "potential prognostic unfavorable (8.34e-4)" "unprognostic (2.24e-1)" "unprognostic (5.58e-2)" "unprognostic (3.18e-2)" "unprognostic (2.65e-1)" "unprognostic (3.88e-2)" "unprognostic (1.07e-1)" "unprognostic (2.19e-2)" "unprognostic (8.52e-2)" BCLAF1 "BTF, KIAA0164" ENSG00000029363 "BCL2 associated transcription factor 1" Q9NYF8 6 136256627-136289851 "Cancer-related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 127.3" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006484, HPA006669, HPA027770" Enhanced Enhanced "Nuclear speckles" NA NA 13000 "Cluster 35: Neutrophils - Protein binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 62 "Nuclear speckles" "HPA006484: , HPA006669: , HPA027770: " "unprognostic (1.19e-1)" "potential prognostic unfavorable (2.68e-4)" "unprognostic (2.40e-1)" "unprognostic (1.18e-1)" "unprognostic (7.63e-3)" "unprognostic (7.05e-2)" "unprognostic (9.61e-3)" "unprognostic (1.33e-2)" "unprognostic (4.96e-2)" "unprognostic (1.56e-3)" "potential prognostic favorable (6.86e-6)" "unprognostic (9.23e-3)" "unprognostic (2.73e-1)" "unprognostic (9.71e-3)" "unprognostic (6.32e-2)" "unprognostic (3.84e-2)" "unprognostic (1.01e-2)" "unprognostic (1.28e-1)" "unprognostic (1.39e-1)" "unprognostic (4.88e-2)" "unprognostic (7.81e-2)" "potential prognostic unfavorable (5.97e-4)" "unprognostic (6.00e-3)" "unprognostic (1.54e-1)" "unprognostic (1.02e-1)" "unprognostic (4.21e-2)" "unprognostic (2.47e-1)" "unprognostic (2.73e-1)" "unprognostic (1.40e-1)" "unprognostic (3.30e-1)" "unprognostic (2.38e-1)" BCLAF3 CXorf23 ENSG00000173681 "BCLAF1 and THRAP3 family member 3" A2AJT9 X 19912860-19991061 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 141.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027215 Approved Approved Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 36: Non-specific - mRNA processing" "Cluster 7: Non-specific - Transcription" Nucleoplasm "HPA027215: " "unprognostic (8.99e-2)" "unprognostic (1.16e-1)" "unprognostic (1.13e-1)" "unprognostic (1.08e-1)" "unprognostic (1.14e-2)" "unprognostic (3.20e-2)" "unprognostic (3.61e-2)" "unprognostic (2.02e-2)" "unprognostic (2.07e-2)" "validated prognostic favorable (3.92e-6)" "validated prognostic favorable (1.53e-4)" "unprognostic (4.72e-2)" "unprognostic (4.62e-2)" "unprognostic (2.03e-2)" "unprognostic (5.53e-2)" "unprognostic (1.42e-1)" "unprognostic (1.08e-1)" "unprognostic (1.12e-1)" "unprognostic (2.32e-2)" "unprognostic (2.50e-1)" "unprognostic (1.02e-2)" "unprognostic (4.12e-1)" "unprognostic (4.40e-2)" "unprognostic (2.02e-1)" "unprognostic (9.41e-2)" "unprognostic (1.78e-1)" "unprognostic (2.92e-1)" "unprognostic (2.17e-2)" "unprognostic (1.08e-1)" BCO1 "BCDO, BCDO1, BCMO, BCMO1, FLJ10730" ENSG00000135697 "Beta-carotene oxygenase 1" Q9HAY6 16 81238689-81291142 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" "Dioxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 11.5;intestine: 13.7" "Cell type enriched" "Detected in many" 13 "Retinal pigment epithelial cells: 375.1" "Cell type enhanced" "Detected in many" "hippocampal CA4: 71.1" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 7.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 5.8" "Adipose visceral - Mesothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA043811 Approved "Actin filaments,Centriolar satellite" NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" "Actin filaments, Centriolar satellite" "HPA043811: " "potential prognostic favorable (7.49e-4)" "unprognostic (1.01e-1)" "unprognostic (6.79e-2)" "unprognostic (8.16e-3)" "unprognostic (1.06e-1)" "unprognostic (2.12e-3)" "unprognostic (2.17e-1)" "unprognostic (6.37e-2)" "unprognostic (5.28e-2)" "unprognostic (2.61e-1)" "unprognostic (3.06e-2)" "unprognostic (7.24e-2)" "unprognostic (1.86e-1)" "unprognostic (2.12e-1)" "unprognostic (9.06e-2)" "unprognostic (1.43e-2)" BCO2 "B-DIOX-II, BCDO2, FLJ34464" ENSG00000197580 "Beta-carotene oxygenase 2" Q9BYV7 11 112175510-112224699 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 44.0;liver: 48.9;retina: 51.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 142.9;Cone photoreceptor cells: 283.6;Ependymal cells: 172.2;Esophageal apical cells: 106.6;Hepatocytes: 185.4;Mesothelial cells: 141.2;Microglia: 134.1;Myonuclei: 147.3;Respiratory ciliated cells: 129.7;Retinal horizontal cells: 122.2;Rod photoreceptor cells: 283.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 7.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 3.8" "Adipose visceral - Mesothelial cells, Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061542 Supported NA NA "Cluster 76: Non-specific - Metabolism" "Cluster 3: Choroid plexus - Cilium" "Cluster 5: Rhabdoid - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" "HPA061542: " "unprognostic (1.31e-1)" "unprognostic (9.05e-3)" "unprognostic (1.44e-1)" "unprognostic (6.59e-2)" "unprognostic (1.98e-2)" "unprognostic (1.01e-1)" "unprognostic (9.91e-2)" "unprognostic (4.07e-2)" "potential prognostic favorable (6.24e-6)" "unprognostic (5.41e-3)" "unprognostic (4.07e-3)" "unprognostic (6.41e-2)" "potential prognostic unfavorable (8.66e-4)" "unprognostic (6.67e-2)" "unprognostic (1.56e-2)" "unprognostic (1.05e-2)" BCOR "FLJ20285, KIAA1575" ENSG00000183337 "BCL6 corepressor" Q6W2J9 X 40049815-40177329 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Cancer-related genes, Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 197.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056308, HPA073591" Enhanced Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 65: Non-specific - Unknown function" "Cluster 85: Squamous epithelial cells - Keratinization" 62 Nucleoplasm "HPA056308: , HPA073591: " "unprognostic (1.10e-1)" "unprognostic (7.21e-2)" "unprognostic (4.01e-1)" "unprognostic (1.16e-1)" "unprognostic (6.54e-2)" "unprognostic (6.40e-3)" "unprognostic (3.10e-1)" "unprognostic (5.11e-2)" "unprognostic (8.09e-3)" "unprognostic (3.26e-2)" "validated prognostic favorable (5.25e-6)" "validated prognostic favorable (4.91e-4)" "unprognostic (2.81e-1)" "potential prognostic unfavorable (2.95e-5)" "unprognostic (1.42e-1)" "unprognostic (1.49e-1)" "unprognostic (2.68e-1)" "unprognostic (9.84e-3)" "unprognostic (2.61e-2)" "unprognostic (6.12e-2)" "unprognostic (7.28e-2)" "unprognostic (2.58e-1)" "unprognostic (2.94e-1)" "unprognostic (3.49e-1)" "unprognostic (3.43e-2)" "unprognostic (1.85e-1)" "unprognostic (2.11e-1)" "unprognostic (4.12e-1)" "unprognostic (1.34e-1)" "unprognostic (1.91e-1)" "unprognostic (1.11e-1)" BCORL1 "CXorf10, FLJ11362" ENSG00000085185 "BCL6 corepressor like 1" Q5H9F3 X 129981107-130058071 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Autism spectrum disorder, Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Neutrophils: 64.5;Oocytes: 152.0;Syncytiotrophoblasts: 197.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031775, HPA031777, HPA068568" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 15: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 13 Nucleoplasm "Plasma membrane" "HPA031775: , HPA031777: , HPA068568: " "unprognostic (1.23e-1)" "unprognostic (9.96e-2)" "unprognostic (9.93e-2)" "unprognostic (4.89e-3)" "unprognostic (3.28e-1)" "unprognostic (1.56e-2)" "unprognostic (2.39e-1)" "unprognostic (1.85e-1)" "unprognostic (5.16e-3)" "unprognostic (1.11e-2)" "potential prognostic favorable (7.26e-5)" "unprognostic (1.51e-2)" "unprognostic (1.56e-1)" "unprognostic (2.54e-3)" "potential prognostic unfavorable (1.42e-5)" "unprognostic (1.51e-1)" "unprognostic (1.90e-2)" "unprognostic (2.65e-2)" "unprognostic (7.97e-3)" "unprognostic (1.38e-1)" "unprognostic (9.59e-2)" "unprognostic (1.68e-1)" "potential prognostic unfavorable (2.26e-5)" "unprognostic (2.82e-1)" "unprognostic (1.07e-1)" "unprognostic (1.67e-1)" "unprognostic (3.71e-1)" "unprognostic (8.09e-2)" "unprognostic (7.45e-2)" "unprognostic (1.23e-1)" "unprognostic (2.33e-1)" BCR "ALL, BCR1, CML, D22S11, D22S662, PHL" ENSG00000186716 "BCR activator of RhoGEF and GTPase" P11274 22 23179704-23318037 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hematopoietic stem cells: 261.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Pituitary gland - Corticotropes, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010421, CAB018545, HPA038337" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 52 "Plasma membrane, Cytosol" Nucleoplasm "CAB010421: , CAB018545: , HPA038337: " "unprognostic (2.63e-1)" "unprognostic (1.81e-2)" "unprognostic (3.54e-1)" "unprognostic (1.83e-1)" "unprognostic (1.52e-3)" "unprognostic (1.54e-1)" "unprognostic (4.45e-2)" "unprognostic (4.34e-3)" "unprognostic (2.67e-1)" "unprognostic (1.99e-2)" "validated prognostic favorable (5.86e-10)" "validated prognostic favorable (1.46e-4)" "unprognostic (2.28e-2)" "unprognostic (5.63e-2)" "unprognostic (1.62e-2)" "unprognostic (3.00e-1)" "unprognostic (2.55e-3)" "unprognostic (1.21e-1)" "unprognostic (3.05e-1)" "unprognostic (1.94e-2)" "unprognostic (2.02e-1)" "unprognostic (9.93e-3)" "unprognostic (7.16e-2)" "unprognostic (1.17e-1)" "unprognostic (7.89e-3)" "unprognostic (4.82e-2)" "unprognostic (3.17e-1)" "unprognostic (1.15e-1)" "unprognostic (1.66e-1)" "unprognostic (8.40e-2)" "unprognostic (2.17e-1)" BCS1L "BCS, BJS, h-BCS, Hs.6719" ENSG00000074582 "BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone" Q9Y276 2 218658764-218663443 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Chaperone, Hydrolase" "Deafness, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 48.0;Esophageal basal cells: 43.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037700, HPA037701" Supported Uncertain "Vesicles,Mid piece" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 70: Non-specific - Protein processing" "Cluster 49: Hindbrain - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 97: Non-specific - Cellular respiration" 12 Vesicles "Mid piece" "HPA037700: , HPA037701: " "unprognostic (2.86e-1)" "unprognostic (5.79e-2)" "unprognostic (2.54e-2)" "unprognostic (3.98e-1)" "unprognostic (4.75e-2)" "unprognostic (1.00e-1)" "unprognostic (1.48e-1)" "unprognostic (1.12e-3)" "unprognostic (2.35e-1)" "unprognostic (2.33e-1)" "unprognostic (1.02e-1)" "unprognostic (6.74e-2)" "unprognostic (1.08e-1)" "unprognostic (1.42e-3)" "unprognostic (5.72e-2)" "unprognostic (1.26e-3)" "unprognostic (4.11e-2)" "unprognostic (4.04e-1)" "unprognostic (2.76e-1)" "unprognostic (1.76e-1)" "unprognostic (1.41e-2)" "unprognostic (2.93e-2)" "unprognostic (6.83e-2)" "unprognostic (2.60e-2)" "unprognostic (3.03e-1)" "unprognostic (3.64e-3)" "unprognostic (9.30e-2)" "unprognostic (2.80e-2)" "unprognostic (2.02e-1)" "unprognostic (3.27e-1)" "unprognostic (3.73e-2)" BDH1 "BDH, SDR9C1" ENSG00000161267 "3-hydroxybutyrate dehydrogenase 1" Q02338 3 197509783-197573323 "Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Allosteric enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 302.0" "Cell type enhanced" "Detected in many" "Astrocytes: 47.1;Bergmann glia: 42.8;Brain excitatory neurons: 83.4;Brain inhibitory neurons: 81.1;Choroid plexus epithelial cells: 137.8;Distal convoluted tubule cells: 69.8;Ependymal cells: 41.8;Hepatocytes: 49.5;Loop of henle epithelial cells: 53.8;Oligodendrocyte progenitor cells: 62.4;Other brain neurons: 50.6;Papillary tip epithelial cells: 31.7;Proximal tubule cells: 32.4;Renal collecting duct intercalated cells: 35.4;Renal collecting duct principal cells: 30.9;Renal connecting tubule cells: 52.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 91.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Prostate - Prostate glandular cells, Skeletal muscle - Skeletal myocytes, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030947, HPA058709" Enhanced Approved Nucleoplasm,Mitochondria NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 53: Liver - Plasma proteins" "Cluster 23: Choroid plexus - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 102: Non-specific - Mixed function" 6 Mitochondria Nucleoplasm "HPA030947: , HPA058709: " "unprognostic (4.97e-1)" "unprognostic (5.25e-3)" "unprognostic (2.18e-1)" "unprognostic (1.02e-2)" "unprognostic (1.71e-1)" "unprognostic (7.36e-3)" "unprognostic (8.87e-2)" "potential prognostic unfavorable (5.80e-4)" "unprognostic (1.41e-1)" "unprognostic (1.67e-2)" "unprognostic (1.15e-1)" "unprognostic (2.05e-2)" "potential prognostic favorable (5.77e-4)" "potential prognostic favorable (1.77e-5)" "unprognostic (1.97e-3)" "unprognostic (2.17e-1)" "unprognostic (3.84e-1)" "unprognostic (2.07e-2)" "unprognostic (5.41e-2)" "unprognostic (3.97e-2)" "unprognostic (5.98e-2)" "unprognostic (1.97e-2)" "unprognostic (2.00e-2)" "unprognostic (7.07e-2)" "unprognostic (2.80e-2)" "potential prognostic unfavorable (2.77e-4)" "unprognostic (1.43e-1)" "unprognostic (1.09e-1)" "unprognostic (1.74e-1)" "unprognostic (5.70e-2)" "unprognostic (1.48e-1)" BDH2 "DHRS6, FLJ13261, PRO20933, SDR15C1, UCPA-OR, UNQ6308" ENSG00000164039 "3-hydroxybutyrate dehydrogenase 2" Q9BUT1 4 103077592-103099870 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 145.9" "Cell type enhanced" "Detected in many" "Enterocytes: 77.5;Epididymal efferent duct absorptive cells: 77.9;Retinal pigment epithelial cells: 68.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Liver - Hepatocytes, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036028, HPA036029" Enhanced Supported Cytosol NA NA 16000 "Cluster 24: Non-specific - Transcription" "Cluster 72: Kidney - Transmembrane transport" "Cluster 19: Astrocytes - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 108: Fibroblasts - ECM organization" 1 Cytosol "HPA036028: , HPA036029: " "unprognostic (1.38e-1)" "unprognostic (3.11e-1)" "unprognostic (4.34e-2)" "unprognostic (8.87e-2)" "unprognostic (1.10e-1)" "unprognostic (4.94e-2)" "unprognostic (2.07e-1)" "unprognostic (2.19e-1)" "unprognostic (2.21e-1)" "unprognostic (2.90e-3)" "validated prognostic favorable (2.02e-14)" "validated prognostic favorable (6.26e-6)" "potential prognostic favorable (1.66e-6)" "unprognostic (1.39e-1)" "potential prognostic favorable (1.24e-4)" "unprognostic (1.20e-2)" "unprognostic (3.12e-1)" "unprognostic (2.84e-1)" "unprognostic (2.08e-1)" "unprognostic (4.03e-1)" "unprognostic (3.04e-2)" "unprognostic (4.61e-2)" "unprognostic (2.11e-1)" "unprognostic (5.75e-2)" "unprognostic (4.03e-2)" "unprognostic (9.26e-2)" "unprognostic (4.22e-2)" "unprognostic (1.97e-2)" "unprognostic (2.78e-1)" "unprognostic (4.51e-3)" "unprognostic (5.91e-2)" BDKRB1 "B1BKR, BKR1, bradyb1" ENSG00000100739 "Bradykinin receptor B1" P46663 14 96256210-96268967 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 21.8" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 36.6;Decidual stromal cells: 12.2;Epicardial cells: 22.7;Epididymal basal cells: 13.6;Esophageal apical cells: 94.3;Esophageal basal cells: 19.3;Esophageal suprabasal cells: 24.8;Fibroblasts: 22.8;Suprabasal keratinocytes: 17.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" HPA002935 Approved NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 35: Non-specific - DNA binding" "Cluster 72: Neuronal - Signal transduction" "Cluster 17: Non-specific - RNA processing" "HPA002935: " "unprognostic (1.20e-1)" "unprognostic (1.82e-2)" "unprognostic (1.78e-1)" "unprognostic (4.14e-2)" "unprognostic (3.55e-1)" "unprognostic (2.70e-1)" "unprognostic (1.31e-2)" "unprognostic (7.27e-3)" "validated prognostic unfavorable (9.01e-4)" "validated prognostic unfavorable (7.15e-5)" "unprognostic (3.17e-2)" "unprognostic (3.80e-1)" "unprognostic (2.23e-2)" "unprognostic (8.52e-2)" "unprognostic (8.02e-3)" "potential prognostic unfavorable (5.94e-4)" "unprognostic (8.05e-3)" "unprognostic (7.93e-2)" "unprognostic (2.63e-1)" "unprognostic (9.03e-2)" "unprognostic (1.21e-1)" BDKRB2 BK-2 ENSG00000168398 "Bradykinin receptor B2" P30411 14 96204679-96244166 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 38.4" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 4.4;Choroid plexus epithelial cells: 2.2;Enterocytes: 1.0;Ependymal cells: 5.5;Esophageal apical cells: 1.6;Oligodendrocytes: 2.8" "Cell type enhanced" "Detected in many" "lower rhombic lip: 13.6;upper rhombic lip: 11.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 18.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA003551, HPA050841" Approved Supported "Vesicles,Plasma membrane,Cytokinetic bridge" Yes NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 2 "Plasma membrane" "Vesicles, Cytokinetic bridge" "HPA003551: , HPA050841: " "unprognostic (9.71e-2)" "unprognostic (1.28e-1)" "unprognostic (6.67e-2)" "unprognostic (1.82e-2)" "unprognostic (6.10e-2)" "unprognostic (1.38e-1)" "unprognostic (2.47e-3)" "unprognostic (5.08e-2)" "unprognostic (2.77e-2)" "potential prognostic favorable (3.26e-4)" "unprognostic (2.19e-1)" "unprognostic (6.58e-2)" "unprognostic (1.39e-2)" "unprognostic (2.44e-1)" "unprognostic (3.76e-2)" "unprognostic (2.33e-1)" "potential prognostic unfavorable (3.28e-4)" "unprognostic (6.00e-2)" "unprognostic (3.79e-2)" "unprognostic (6.90e-3)" "unprognostic (1.80e-1)" "unprognostic (1.99e-1)" "unprognostic (5.16e-2)" "unprognostic (2.84e-1)" "unprognostic (2.07e-1)" "unprognostic (9.48e-2)" "unprognostic (5.34e-2)" "unprognostic (1.04e-2)" "unprognostic (2.51e-1)" "unprognostic (4.02e-2)" "unprognostic (1.64e-1)" BDNF ENSG00000176697 "Brain derived neurotrophic factor" P23560 11 27654893-27722058 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 56.9;Brain excitatory neurons: 63.7;Cardiomyocytes: 78.4;Corticotrophs: 74.4;Epicardial cells: 59.1;Epididymal principal cells: 56.1;Granulosa cells: 27.6;Megakaryocytes: 37.1;Myonuclei: 29.4;Retinal bipolar cells: 30.3" "Cell type enhanced" "Detected in many" "hippocampal dentate gyrus: 336.0;mammillary body: 126.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 27.6" "Lung - Alveolar cells type 1, Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Smooth muscle cells, Skin - Outer root sheath cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" CAB009564 Enhanced "Secreted to blood" "Growth factor" NA Yes 16000000 12000 "Cluster 35: Non-specific - Mixed function" "Cluster 29: Forebrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 35: Neurons - Synaptic function & neurogenesis" 9 "CAB009564: " "unprognostic (2.25e-1)" "unprognostic (8.18e-2)" "unprognostic (1.78e-2)" "unprognostic (5.11e-2)" "potential prognostic favorable (5.82e-5)" "unprognostic (3.29e-3)" "unprognostic (4.80e-3)" "unprognostic (7.21e-2)" "unprognostic (4.42e-2)" "unprognostic (2.15e-2)" "unprognostic (1.71e-1)" "unprognostic (1.02e-1)" "unprognostic (1.06e-1)" BDP1 "HSA238520, KIAA1241, KIAA1689, TAF3B1, TFC5, TFIIIB150, TFIIIB90, TFNR" ENSG00000145734 "B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB" A6H8Y1 5 71455651-71567820 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Distal convoluted tubule cells: 197.3;Proximal tubule cells: 196.7;Renal collecting duct intercalated cells: 219.5;Renal connecting tubule cells: 184.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064166, HPA077984" Enhanced Nucleoplasm NA NA "Cluster 42: Retina - Visual perception" "Cluster 37: Neurons - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 102: Non-specific - Mixed function" 4 Nucleoplasm "HPA064166: , HPA077984: " "unprognostic (9.23e-3)" "unprognostic (8.08e-2)" "unprognostic (9.05e-2)" "unprognostic (1.58e-2)" "unprognostic (1.50e-1)" "unprognostic (3.58e-1)" "unprognostic (2.23e-2)" "unprognostic (1.85e-1)" "unprognostic (3.11e-1)" "unprognostic (3.85e-2)" "unprognostic (4.31e-1)" "unprognostic (1.50e-1)" "unprognostic (2.49e-3)" "unprognostic (1.06e-2)" "unprognostic (1.78e-1)" BEAN1 SCA31 ENSG00000166546 "Brain expressed associated with NEDD4 1" Q3B7T3 16 66427295-66493529 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.4" "Cell type enhanced" "Detected in many" "Adipocytes: 43.4;Early spermatids: 51.2;Epicardial cells: 40.9;Extravillous trophoblasts: 36.1;Retinal ganglion cells: 108.2;Retinal horizontal cells: 38.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 4.8" "Adipose visceral - Mesothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053851 Uncertain Uncertain Nucleoplasm,Centrosome NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 24: Neurons - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" Nucleoplasm Centrosome "HPA053851: " "unprognostic (5.37e-3)" "unprognostic (1.70e-1)" "unprognostic (1.02e-1)" "unprognostic (1.04e-1)" "unprognostic (1.20e-3)" "unprognostic (1.36e-1)" "unprognostic (5.48e-2)" "unprognostic (2.63e-2)" "unprognostic (2.04e-1)" "unprognostic (7.85e-3)" "unprognostic (2.14e-3)" "unprognostic (1.99e-1)" "unprognostic (2.34e-1)" "unprognostic (3.64e-2)" "unprognostic (8.58e-2)" BECN1 "ATG6, VPS30" ENSG00000126581 "Beclin 1" Q14457 17 42810134-42833350 "Predicted intracellular proteins, Transporters" "Antiviral defense, Apoptosis, Autophagy, Cell cycle, Cell division, Endocytosis, Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003949, CAB010143, HPA028949" Supported Supported "Nuclear bodies,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 27: Breast cancer - Unknown function" "Cluster 17: Non-specific - RNA processing" 130 Cytosol "Nuclear bodies" "CAB010143: , HPA003949: , HPA028949: " "unprognostic (2.90e-2)" "unprognostic (9.38e-2)" "unprognostic (1.70e-1)" "unprognostic (2.61e-1)" "unprognostic (2.87e-1)" "unprognostic (1.32e-2)" "unprognostic (1.89e-1)" "unprognostic (2.08e-1)" "unprognostic (2.01e-3)" "unprognostic (4.93e-3)" "potential prognostic favorable (5.20e-5)" "unprognostic (4.73e-2)" "unprognostic (1.72e-1)" "unprognostic (3.76e-2)" "unprognostic (4.01e-3)" "unprognostic (2.00e-1)" "unprognostic (3.30e-1)" "unprognostic (1.31e-1)" "unprognostic (2.09e-1)" "unprognostic (5.30e-2)" "potential prognostic unfavorable (5.45e-4)" "unprognostic (4.13e-1)" "unprognostic (7.26e-2)" "unprognostic (1.34e-1)" "unprognostic (1.01e-2)" "unprognostic (1.52e-1)" "unprognostic (4.97e-2)" "unprognostic (6.25e-2)" "unprognostic (1.54e-1)" "unprognostic (2.01e-1)" "unprognostic (2.10e-3)" BECN2 BECN1P1 ENSG00000196289 "Beclin 2" A8MW95 1 241957767-241959062 "Predicted intracellular proteins" Autophagy "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 16: Thyroid cancer - Neuronal signaling" 4 BEGAIN KIAA1446 ENSG00000183092 "Brain enriched guanylate kinase associated" Q9BUH8 14 100537147-100587417 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 53.7;pancreas: 22.6;pituitary gland: 18.8" "Cell type enriched" "Detected in many" 8 "Retinal horizontal cells: 318.5" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 5.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 2.8" "Lineage enriched" "Detected in single" 5 "granulocytes: 2.8" "Cancer enhanced" "Detected in many" "cervical cancer: 11.6;Neuroblastoma: 16.6" "Adrenal gland - Adrenal medulla cells, Minor Salivary Gland - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002899 Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 27: Cerebellum - Synaptic function" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 33 Nucleoplasm "Golgi apparatus, Cytosol" "HPA002899: " "potential prognostic favorable (1.57e-4)" "unprognostic (7.44e-2)" "unprognostic (9.28e-3)" "unprognostic (1.25e-1)" "unprognostic (3.40e-2)" "unprognostic (2.74e-1)" "unprognostic (5.64e-2)" "unprognostic (1.55e-2)" "unprognostic (1.25e-1)" "unprognostic (9.51e-2)" "unprognostic (6.31e-2)" "unprognostic (2.57e-2)" "unprognostic (4.13e-1)" "unprognostic (3.08e-1)" "unprognostic (1.42e-1)" BEND2 "CXorf20, MGC33653" ENSG00000177324 "BEN domain containing 2" Q8NDZ0 X 18162931-18220886 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 19 "testis: 5.0" "Group enriched" "Detected in some" 8 "Early primary spermatocytes: 124.5;Platelets: 313.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 2.5" "Lineage enriched" "Detected in single" 21 "granulocytes: 2.5" "Cancer enriched" "Detected in single" 10 "Rhabdoid: 1.0" "Pituitary gland - Corticotropes, Testis - Spermatocytes" "HPA009420, HPA013142" Enhanced NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 48: Non-specific - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 3: Early primary spermatocytes - Early meiosis" 3 "HPA009420: , HPA013142: " BEND3 KIAA1553 ENSG00000178409 "BEN domain containing 3" Q5T5X7 6 107065182-107115515 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Respiratory deuterosomal cells: 13.5;Respiratory ionocytes: 12.7" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 4 "Testicular Germ Cell Tumor (TCGA): 17.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Pituitary gland - Corticotropes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA017891, HPA062067" Uncertain Approved Nucleoplasm NA NA "Cluster 21: Testis - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 75: Non-specific - Chaperones and protein folding" 12 Nucleoplasm "HPA017891: , HPA062067: " "unprognostic (1.09e-1)" "unprognostic (1.08e-2)" "unprognostic (2.43e-2)" "unprognostic (1.19e-1)" "unprognostic (5.12e-3)" "unprognostic (3.86e-2)" "unprognostic (6.92e-2)" "potential prognostic favorable (7.08e-4)" "unprognostic (1.40e-1)" "unprognostic (2.11e-2)" "potential prognostic unfavorable (8.21e-4)" "unprognostic (2.53e-1)" "unprognostic (4.31e-2)" "unprognostic (1.96e-1)" "unprognostic (1.24e-2)" "unprognostic (2.05e-1)" "unprognostic (4.30e-3)" "unprognostic (8.26e-2)" "unprognostic (1.45e-1)" "unprognostic (9.27e-2)" "unprognostic (1.03e-2)" "unprognostic (2.12e-2)" "unprognostic (1.35e-1)" "unprognostic (2.78e-2)" "unprognostic (1.70e-1)" "unprognostic (7.10e-2)" "unprognostic (1.75e-2)" BEND4 "CCDC4, FLJ35632, FLJ43965" ENSG00000188848 "BEN domain containing 4" Q6ZU67 4 42110853-42152878 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "prostate: 2.9;testis: 8.8" "Cell type enhanced" "Detected in some" "B-cells: 17.0;Differentiating spermatogonia: 48.2;Hematopoietic stem cells: 18.9;Lactotrophs: 18.2;Megakaryocyte progenitors: 14.3;Megakaryocyte-Erythroid progenitors: 13.6;Müller glia: 32.3;Prostatic glandular cells: 24.0;Retinal horizontal cells: 12.0;Thymocytes: 10.2;Undifferentiated spermatogonia: 71.2" "Cell type enhanced" "Detected in many" "CGE interneuron: 14.2;midbrain-derived inhibitory: 15.4" "Group enriched" "Detected in some" 41 "Prostate Adenocarcinoma (TCGA): 8.8;Testicular Germ Cell Tumor (TCGA): 8.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Leukemia: 4.5;lymphoma: 8.7;Neuroblastoma: 7.0;prostate cancer: 5.7;testis cancer: 13.9" "Prostate - Prostate glandular cells, Spleen - B-cells (Spleen), Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA036850 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 39: Testis - Nuclear processes" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "HPA036850: " "unprognostic (1.33e-3)" "unprognostic (2.14e-1)" "unprognostic (1.57e-1)" BEND5 "C1orf165, FLJ11588" ENSG00000162373 "BEN domain containing 5" Q7L4P6 1 48727519-48776969 "Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 31.0;Conjunctival goblet cells: 20.4;Epididymal efferent duct absorptive cells: 24.6;Medullary thymic epithelial cells: 45.6;Peritubular myoid cells: 16.5;Respiratory basal cells: 27.7;Respiratory secretory cells: 44.1" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 4.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 6.5;naive B-cell: 8.1" "Lineage enriched" "Detected in many" 5 "B-cells: 8.1" "Cancer enhanced" "Detected in some" "Neuroblastoma: 3.8" "Liver - Hepatic stellate cells, Prostate - Fibroblasts, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA054347, HPA058007" Uncertain Approved "Nuclear speckles,Cytosol" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 65: Brain - Transcription" "Cluster 24: Neurons - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 19 "Nuclear speckles" Cytosol "HPA054347: , HPA058007: " "unprognostic (6.90e-2)" "unprognostic (1.38e-1)" "unprognostic (1.56e-3)" "potential prognostic favorable (8.82e-6)" "unprognostic (1.05e-3)" "unprognostic (3.65e-3)" "unprognostic (1.93e-1)" "unprognostic (1.63e-2)" "unprognostic (2.58e-1)" "unprognostic (2.07e-1)" "unprognostic (1.25e-1)" "unprognostic (2.04e-2)" "unprognostic (1.12e-1)" BEND6 "bA203B9.1, C6orf65, FLJ30162" ENSG00000151917 "BEN domain containing 6" Q5SZJ8 6 56955107-57027346 "Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 44.7" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 133.6;Brain inhibitory neurons: 105.8;Oligodendrocyte progenitor cells: 68.9;Other brain neurons: 77.8;Retinal amacrine cells: 80.1;Retinal bipolar cells: 156.7;Retinal ganglion cells: 73.4;Retinal horizontal cells: 58.1" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 6 "Glioblastoma Multiforme (TCGA): 14.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "plasmacytoid DC: 8.8" "Lineage enriched" "Detected in many" 6 "dendritic cells: 8.8" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031605, HPA052973" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 27: Cerebellum - Synaptic function" "Cluster 37: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "Nucleoplasm, Plasma membrane" "HPA031605: , HPA052973: " "unprognostic (1.77e-1)" "unprognostic (2.71e-1)" "unprognostic (2.30e-1)" "unprognostic (1.19e-1)" "unprognostic (4.02e-3)" "unprognostic (3.70e-1)" "unprognostic (3.60e-1)" "unprognostic (2.75e-1)" "unprognostic (1.11e-1)" "potential prognostic unfavorable (4.29e-5)" "unprognostic (2.65e-3)" "unprognostic (1.34e-1)" "validated prognostic unfavorable (7.60e-4)" "validated prognostic unfavorable (3.90e-4)" "unprognostic (9.23e-2)" "unprognostic (1.24e-1)" "unprognostic (1.41e-1)" "unprognostic (2.85e-2)" "unprognostic (1.61e-2)" "unprognostic (1.17e-1)" "unprognostic (3.75e-2)" "unprognostic (5.33e-2)" "unprognostic (2.91e-2)" "potential prognostic unfavorable (4.01e-4)" "unprognostic (9.60e-2)" "unprognostic (5.51e-2)" "unprognostic (3.38e-3)" BEND7 "C10orf30, FLJ40283" ENSG00000165626 "BEN domain containing 7" Q8N7W2 10 13438484-13529014 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 254.6;Epididymal efferent duct absorptive cells: 230.9;Late spermatids: 512.3;Pituitary stem cells: 229.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Minor salivary glandular cells, Spleen - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA037835 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center,Vesicles" Yes No "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 51: Secretory epithelial cells - Mixed function" 8 "Nucleoplasm, Nucleoli fibrillar center" Vesicles "HPA037835: " "unprognostic (8.85e-2)" "unprognostic (8.39e-2)" "unprognostic (1.09e-2)" "unprognostic (1.85e-1)" "unprognostic (2.76e-1)" "unprognostic (1.84e-1)" "unprognostic (5.40e-2)" "potential prognostic favorable (1.04e-5)" "potential prognostic unfavorable (2.18e-4)" "unprognostic (6.48e-2)" "potential prognostic favorable (1.13e-4)" "unprognostic (1.70e-2)" "unprognostic (1.18e-1)" "unprognostic (3.37e-3)" "unprognostic (3.10e-2)" "unprognostic (7.72e-2)" "unprognostic (9.44e-3)" "unprognostic (5.91e-3)" "unprognostic (1.15e-2)" "unprognostic (1.06e-1)" "unprognostic (2.07e-1)" "unprognostic (1.82e-1)" "unprognostic (4.93e-3)" "unprognostic (1.71e-1)" "potential prognostic favorable (3.94e-4)" "unprognostic (4.76e-2)" "unprognostic (6.68e-2)" "unprognostic (1.03e-1)" "unprognostic (1.90e-1)" "unprognostic (5.21e-2)" "unprognostic (2.44e-2)" BEST1 "BEST, BMD, RP50, VMD2" ENSG00000167995 "Bestrophin 1" O76090 11 61950063-61965515 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Transport, Vision" "Chloride channel, Ion channel" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 24.8;brain: 31.3" "Group enriched" "Detected in many" 5 "Epicardial cells: 998.3;Retinal pigment epithelial cells: 2067.5" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 69.2;oligodendrocyte: 70.7" "Group enriched" "Detected in many" 21 "Prostate Adenocarcinoma (TCGA): 186.9;Uterine Corpus Endometrial Carcinoma (TCGA): 667.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 37.8" "Lineage enriched" "Detected in many" 7 "granulocytes: 37.8" "Cancer enriched" "Detected in many" 4 "skin cancer: 18.3" "Adipose subcutaneous - Macrophages, Spleen - Neutrophils_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA057464 Enhanced NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" 2 "HPA057464: " "unprognostic (1.16e-2)" "unprognostic (7.38e-2)" "unprognostic (4.50e-2)" "potential prognostic favorable (2.75e-4)" "unprognostic (3.21e-2)" "unprognostic (2.46e-1)" "unprognostic (1.55e-2)" "unprognostic (3.56e-1)" "potential prognostic unfavorable (9.29e-7)" "validated prognostic unfavorable (3.35e-5)" "validated prognostic unfavorable (8.62e-4)" "unprognostic (1.52e-1)" "unprognostic (1.06e-2)" "unprognostic (9.35e-2)" "unprognostic (3.22e-2)" "unprognostic (7.11e-2)" "unprognostic (1.68e-1)" "unprognostic (7.95e-2)" "unprognostic (6.49e-2)" "unprognostic (3.06e-2)" "unprognostic (2.58e-1)" "unprognostic (1.51e-1)" "unprognostic (1.56e-1)" "unprognostic (2.68e-1)" "unprognostic (3.35e-3)" "unprognostic (1.54e-1)" "unprognostic (2.02e-1)" "unprognostic (1.15e-1)" BEST2 "FLJ20132, VMD2L1" ENSG00000039987 "Bestrophin 2" Q8NFU1 19 12751702-12758458 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "intestine: 42.7;skin 1: 16.9" "Cell type enriched" "Detected in some" 21 "Goblet cells: 145.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enterocytes, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 2.0" HPA046229 Approved Approved "Flagellar centriole,Principal piece,End piece" NA NA "Cluster 77: Intestine - Digestion" "Cluster 25: Non-specific - Transcription" "Cluster 56: Non-specific - Sensory perception" "Cluster 70: Intestinal goblet cells - Mucin production" 14 "Flagellar centriole, Principal piece, End piece" "HPA046229: " "unprognostic (2.46e-2)" "unprognostic (5.41e-3)" "unprognostic (1.27e-1)" "unprognostic (2.06e-3)" "unprognostic (1.23e-1)" "potential prognostic unfavorable (8.29e-4)" "unprognostic (5.58e-2)" BEST3 "MGC13168, MGC40411, VMD2L3" ENSG00000127325 "Bestrophin 3" Q8N1M1 12 69643360-69699476 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "skeletal muscle: 66.8;tongue: 52.0" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 123.1;Corticotrophs: 48.4;Myonuclei: 509.6;Myosatellite cells: 141.8;Oligodendrocyte progenitor cells: 86.0;Respiratory ionocytes: 66.0;Thymic myoid cells: 373.9" "Cell type enriched" "Detected in many" 4 "oligodendrocyte precursor cell: 109.9" "Cancer enriched" "Detected in some" 5 "Glioblastoma Multiforme (TCGA): 14.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "lymphoma: 34.8" "Pancreas - Beta cells, Pituitary gland - Corticotropes, Prostate - Prostate glandular cells, Skin - Inner root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA054582 Approved NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 46: Skeletal myocytes - Muscle structure & formation" "HPA054582: " "unprognostic (9.87e-3)" "unprognostic (1.33e-1)" "unprognostic (6.23e-2)" "unprognostic (8.37e-3)" "validated prognostic favorable (5.33e-4)" "validated prognostic favorable (4.85e-4)" "unprognostic (6.82e-3)" "unprognostic (2.23e-2)" "unprognostic (4.52e-2)" "unprognostic (6.44e-2)" "unprognostic (2.03e-1)" BEST4 VMD2L2 ENSG00000142959 "Bestrophin 4" Q8NFU0 1 44783585-44788170 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "choroid plexus: 13.8;fallopian tube: 7.5;intestine: 20.8" "Cell type enhanced" "Detected in some" "Colonocytes: 419.6;Endometrial ciliated cells: 55.4;Enterocytes: 115.8;Ependymal cells: 40.2;Epididymal efferent duct ciliated cells: 88.6;Fallopian tube ciliated cells: 31.6;Respiratory ciliated cells: 66.8" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 27.9;ependymal cell: 42.4" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in all" 4 "choroid plexus: 37.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" HPA058564 Approved NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" "HPA058564: " "unprognostic (7.72e-2)" "unprognostic (2.82e-2)" "unprognostic (2.83e-2)" "unprognostic (2.32e-2)" "potential prognostic unfavorable (1.66e-4)" "unprognostic (4.40e-2)" "unprognostic (2.29e-3)" "unprognostic (1.85e-1)" "unprognostic (1.41e-2)" "unprognostic (3.55e-2)" "unprognostic (1.41e-1)" "unprognostic (3.01e-1)" BET1 hbet1 ENSG00000105829 "Bet1 golgi vesicular membrane trafficking protein" O15155 7 93962762-94004382 "Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, Protein transport, Transport" "Congenital muscular dystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epididymal principal cells: 153.4;Extravillous trophoblasts: 261.2;Lactotrophs: 151.7;Syncytiotrophoblasts: 163.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pituitary gland - Lactotropes" "Low region specificity" "Detected in all" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 22: Epididymis - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 39: Non-specific - Transcription" "Cluster 8: Non-specific - Secretory pathway" 92 "unprognostic (1.19e-2)" "unprognostic (1.48e-1)" "unprognostic (2.71e-2)" "unprognostic (4.52e-2)" "unprognostic (6.84e-2)" "unprognostic (1.11e-1)" "potential prognostic unfavorable (6.59e-6)" "unprognostic (4.19e-3)" "unprognostic (1.03e-2)" "unprognostic (1.76e-1)" "unprognostic (1.80e-3)" "unprognostic (1.18e-2)" "unprognostic (3.07e-3)" "unprognostic (1.09e-2)" "unprognostic (3.33e-2)" "unprognostic (1.27e-1)" "unprognostic (2.48e-1)" "unprognostic (5.90e-2)" "unprognostic (8.69e-2)" "unprognostic (3.92e-2)" "unprognostic (9.24e-3)" "unprognostic (2.33e-2)" "potential prognostic unfavorable (6.60e-4)" "unprognostic (1.10e-1)" "unprognostic (3.88e-3)" "unprognostic (3.97e-3)" "unprognostic (2.33e-1)" "unprognostic (4.16e-2)" "unprognostic (3.45e-1)" "unprognostic (2.14e-1)" "unprognostic (1.01e-1)" BET1L "GOLIM3, GS15" ENSG00000177951 "Bet1 golgi vesicular membrane trafficking protein like" Q9NYM9 11 167784-207399 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 232.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039819 Approved Supported "Nucleoplasm,Golgi apparatus" No No "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 15: Bone marrow - Innate immune response" "Cluster 11: White matter - Signal transduction" "Cluster 63: Non-specific - Protein processing" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 18 "Golgi apparatus" Nucleoplasm "HPA039819: " "unprognostic (7.90e-3)" "unprognostic (3.81e-2)" "unprognostic (8.16e-3)" "unprognostic (2.29e-2)" "unprognostic (1.43e-1)" "unprognostic (1.38e-2)" "validated prognostic unfavorable (5.86e-4)" "validated prognostic unfavorable (1.77e-4)" "unprognostic (3.23e-1)" "unprognostic (2.06e-2)" "potential prognostic favorable (3.23e-5)" "unprognostic (6.31e-2)" "unprognostic (7.02e-2)" "potential prognostic unfavorable (1.35e-4)" "unprognostic (3.11e-2)" "unprognostic (1.46e-1)" "unprognostic (1.76e-2)" "unprognostic (6.57e-2)" "unprognostic (1.50e-1)" "unprognostic (5.04e-2)" "unprognostic (3.87e-3)" "unprognostic (8.31e-2)" "unprognostic (5.70e-2)" "unprognostic (2.18e-1)" "unprognostic (1.92e-1)" "unprognostic (6.25e-2)" "unprognostic (1.26e-1)" "unprognostic (1.71e-1)" "unprognostic (1.78e-1)" "unprognostic (9.65e-2)" "unprognostic (2.17e-1)" BEX1 ENSG00000133169 "Brain expressed X-linked 1" Q9HBH7 X 103062651-103064171 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 602.9;pituitary gland: 418.3" "Cell type enhanced" "Detected in many" "Epididymal efferent duct absorptive cells: 186.4;Granulosa cells: 733.1;Müller glia: 445.5;Neuroendocrine cells: 150.3;Other brain neurons: 257.0;Pancreatic duct cells: 198.9;Pancreatic islet cells: 533.2;Retinal bipolar cells: 183.0;Retinal horizontal cells: 240.4;Sertoli cells: 259.2" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 4 "Glioblastoma Multiforme (TCGA): 236.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 3.4" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Neuroblastoma: 312.9" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "HPA045384, HPA078630" Approved Approved Cytosol NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 14: Neurons - Synaptic function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 13 Cytosol "HPA045384: , HPA078630: " "unprognostic (2.51e-2)" "potential prognostic favorable (3.72e-4)" "unprognostic (3.47e-2)" "unprognostic (4.12e-1)" "unprognostic (1.73e-1)" "unprognostic (2.65e-3)" "unprognostic (1.45e-1)" "unprognostic (1.27e-1)" "potential prognostic favorable (2.16e-5)" "unprognostic (9.22e-2)" "unprognostic (1.33e-2)" "unprognostic (1.93e-1)" "unprognostic (3.36e-2)" "unprognostic (2.00e-1)" "unprognostic (5.18e-3)" "unprognostic (1.98e-1)" "unprognostic (1.64e-1)" "unprognostic (1.55e-2)" "unprognostic (4.31e-1)" "potential prognostic favorable (7.06e-4)" "unprognostic (6.50e-2)" "unprognostic (2.52e-1)" "unprognostic (1.49e-1)" "unprognostic (2.08e-3)" "unprognostic (1.07e-1)" "potential prognostic unfavorable (2.92e-4)" "unprognostic (3.81e-1)" BEX2 DJ79P11.1 ENSG00000133134 "Brain expressed X-linked 2" Q9BXY8 X 103309346-103311007 "Predicted intracellular proteins" "Apoptosis, Cell cycle" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 301.2;pituitary gland: 199.0" "Cell type enhanced" "Detected in many" "Epididymal basal cells: 417.5;Epididymal efferent duct absorptive cells: 320.2;Epididymal principal cells: 239.1;Müller glia: 203.2;Pancreatic islet cells: 220.9" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Thyroid Carcinoma (TCGA): 135.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 52.9;NK-cells: 62.2;T-cells: 68.8" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "HPA045384, HPA078630" Uncertain Uncertain Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 22: Epididymis - Mixed function" "Cluster 14: Neurons - Synaptic function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 98: Neurons - Neurotransmission & signaling" 73 Cytosol "HPA045384: , HPA078630: " "unprognostic (1.34e-2)" "unprognostic (4.35e-2)" "unprognostic (9.87e-3)" "unprognostic (2.86e-1)" "unprognostic (7.71e-3)" "unprognostic (6.24e-2)" "unprognostic (1.47e-1)" "unprognostic (2.71e-1)" "unprognostic (1.97e-1)" "unprognostic (1.26e-1)" "potential prognostic favorable (2.98e-7)" "unprognostic (1.10e-2)" "potential prognostic favorable (1.03e-7)" "unprognostic (1.85e-2)" "unprognostic (6.35e-2)" "unprognostic (4.21e-3)" "unprognostic (7.01e-2)" "unprognostic (2.22e-2)" "unprognostic (8.16e-2)" "unprognostic (1.11e-1)" "unprognostic (1.69e-1)" "unprognostic (7.12e-3)" "unprognostic (6.40e-3)" "unprognostic (7.00e-2)" "unprognostic (1.45e-1)" "unprognostic (3.83e-2)" "unprognostic (2.90e-2)" "unprognostic (1.02e-2)" "unprognostic (2.19e-2)" "unprognostic (2.74e-1)" "unprognostic (5.57e-2)" BEX3 "Bex, DXS6984E, HGR74, NADE, NGFRAP1" ENSG00000166681 "Brain expressed X-linked 3" Q00994 X 103376395-103378164 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 829.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1863.6;Decidual stromal cells: 845.0;Epididymal basal cells: 814.8;Epididymal principal cells: 2036.4;Granulosa cells: 886.4;Migrating cytotrophoblasts: 1467.4;Peritubular myoid cells: 973.2;Platelets: 1458.2;Syncytiotrophoblasts: 841.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 151.3;T-reg: 137.6" "Lineage enriched" "Detected in all" 5 "T-cells: 151.3" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018886 Approved Supported Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 65: Brain - Transcription" "Cluster 23: Choroid plexus - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 27 Cytosol "HPA018886: " "unprognostic (9.39e-2)" "unprognostic (1.90e-1)" "unprognostic (2.60e-2)" "unprognostic (1.08e-1)" "unprognostic (1.15e-1)" "unprognostic (3.78e-1)" "unprognostic (2.28e-2)" "unprognostic (1.60e-3)" "unprognostic (1.59e-1)" "potential prognostic favorable (4.08e-5)" "unprognostic (2.65e-2)" "unprognostic (2.83e-1)" "unprognostic (4.53e-2)" "unprognostic (7.15e-2)" "unprognostic (2.97e-2)" "unprognostic (6.31e-3)" "unprognostic (1.02e-1)" "unprognostic (4.09e-2)" "unprognostic (5.75e-2)" "unprognostic (6.31e-3)" "unprognostic (7.00e-2)" "unprognostic (3.75e-1)" "unprognostic (1.96e-1)" "unprognostic (1.37e-1)" "unprognostic (6.68e-2)" "potential prognostic unfavorable (7.65e-5)" "unprognostic (1.78e-1)" "unprognostic (1.87e-2)" "unprognostic (5.23e-3)" BEX4 "BEXL1, FLJ10097" ENSG00000102409 "Brain expressed X-linked 4" Q9NWD9 X 103215108-103217246 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 354.6;Epididymal basal cells: 348.7;Epididymal principal cells: 618.3;Esophageal apical cells: 610.6;Megakaryocytes: 426.5;Migrating cytotrophoblasts: 328.5;Syncytiotrophoblasts: 440.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "testis cancer: 85.7" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045105, HPA051935" Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 41: Basophils - Unknown function" "Cluster 22: Epididymis - Mixed function" "Cluster 14: Neurons - Synaptic function" "Cluster 47: Leukemia - Hemostasis" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 1 "Nucleoplasm, Cytosol" "HPA045105: , HPA051935: " "unprognostic (1.91e-1)" "unprognostic (1.29e-1)" "potential prognostic unfavorable (1.21e-4)" "unprognostic (6.55e-2)" "unprognostic (1.18e-1)" "unprognostic (2.19e-2)" "unprognostic (1.10e-1)" "potential prognostic favorable (7.71e-4)" "unprognostic (2.03e-1)" "potential prognostic favorable (9.53e-4)" "potential prognostic favorable (3.60e-7)" "unprognostic (2.26e-3)" "potential prognostic favorable (3.66e-5)" "unprognostic (8.01e-2)" "unprognostic (4.84e-2)" "potential prognostic favorable (2.34e-6)" "unprognostic (3.48e-1)" "unprognostic (1.46e-1)" "unprognostic (1.64e-1)" "unprognostic (2.01e-1)" "unprognostic (4.02e-2)" "unprognostic (1.12e-3)" "unprognostic (4.20e-3)" "unprognostic (1.53e-1)" "unprognostic (1.45e-3)" "unprognostic (3.46e-2)" "unprognostic (1.51e-1)" "unprognostic (3.71e-3)" "unprognostic (1.20e-2)" "unprognostic (5.75e-2)" "unprognostic (4.40e-1)" BEX5 NGFRAP1L1 ENSG00000184515 "Brain expressed X-linked 5" Q5H9J7 X 102153708-102155977 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 150.4;pituitary gland: 82.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 129.5;Epididymal efferent duct absorptive cells: 79.4;Epididymal principal cells: 71.1;Gastric chief cells: 133.2;Granulosa cells: 77.9;Neuroendocrine cells: 62.4;Pancreatic islet cells: 61.7;Parietal cells: 86.6;Plasma cells: 67.7" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Uterine Corpus Endometrial Carcinoma (TCGA): 97.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 6.2;MAIT T-cell: 15.5;memory CD4 T-cell: 11.6;memory CD8 T-cell: 8.1;naive CD4 T-cell: 16.5;naive CD8 T-cell: 10.1;NK-cell: 10.1;T-reg: 11.9" "Group enriched" "Detected in many" 6 "NK-cells: 10.1;T-cells: 16.5" "Cancer enhanced" "Detected in many" "Myeloma: 24.3" "Adrenal gland - Adrenal medulla cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" HPA059058 Enhanced NA NA "Cluster 11: T-cells - Unknown function" "Cluster 78: Brain - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 18 "HPA059058: " "unprognostic (9.23e-2)" "unprognostic (1.10e-1)" "unprognostic (1.46e-1)" "unprognostic (1.95e-2)" "unprognostic (7.87e-2)" "unprognostic (1.64e-2)" "unprognostic (4.41e-3)" "unprognostic (1.35e-2)" "unprognostic (9.77e-2)" "potential prognostic unfavorable (7.54e-4)" "validated prognostic favorable (2.48e-5)" "validated prognostic favorable (3.59e-4)" "unprognostic (1.51e-1)" "unprognostic (8.22e-2)" "unprognostic (6.31e-3)" "potential prognostic favorable (2.99e-4)" "unprognostic (2.77e-1)" "unprognostic (4.61e-2)" "unprognostic (3.15e-1)" "unprognostic (8.86e-2)" "unprognostic (2.36e-2)" "unprognostic (1.61e-3)" "unprognostic (1.18e-1)" "unprognostic (1.24e-2)" "unprognostic (7.21e-2)" "unprognostic (1.00e-2)" "unprognostic (6.76e-2)" "unprognostic (2.91e-1)" "unprognostic (1.97e-1)" "unprognostic (9.83e-3)" "unprognostic (5.35e-2)" BFAR "BAR, RNF47" ENSG00000103429 "Bifunctional apoptosis regulator" Q9NZS9 16 14632931-14669236 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 30.0;Microglia: 24.5;Oligodendrocytes: 22.1;Papillary tip epithelial cells: 23.7;Podocytes: 24.0;Proximal tubule cells: 49.8;Renal collecting duct intercalated cells: 30.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 24: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 54: Non-specific - Transcription" "Cluster 102: Non-specific - Mixed function" 13 "unprognostic (3.45e-2)" "unprognostic (6.81e-2)" "unprognostic (7.40e-2)" "unprognostic (2.68e-2)" "unprognostic (2.82e-1)" "unprognostic (1.83e-2)" "unprognostic (1.25e-1)" "unprognostic (8.87e-2)" "unprognostic (6.51e-3)" "unprognostic (7.72e-2)" "potential prognostic favorable (3.20e-8)" "unprognostic (1.35e-1)" "unprognostic (2.22e-2)" "unprognostic (1.43e-2)" "potential prognostic unfavorable (5.23e-4)" "unprognostic (4.08e-2)" "unprognostic (1.97e-1)" "unprognostic (6.40e-2)" "unprognostic (3.93e-1)" "unprognostic (1.86e-1)" "unprognostic (1.43e-3)" "potential prognostic unfavorable (3.52e-4)" "unprognostic (6.94e-2)" "unprognostic (8.66e-2)" "potential prognostic favorable (1.46e-4)" "unprognostic (1.72e-1)" "unprognostic (2.70e-1)" "unprognostic (1.82e-3)" "unprognostic (2.79e-1)" "unprognostic (1.17e-1)" "unprognostic (2.20e-1)" BFSP1 "CP115, CP94, filensin, LIFL-H" ENSG00000125864 "Beaded filament structural protein 1" Q12934 20 17493905-17569220 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Eye lens protein" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 21.1;Alveolar cells type 2: 16.8;Cardiomyocytes: 12.5;Transitional alveolar cells: 16.6;Undifferentiated spermatogonia: 29.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 2.5" "Lineage enhanced" "Detected in single" "T-cells: 2.5" "Low cancer specificity" "Detected in many" "Skeletal muscle - Fibroblasts, Skin - Outer root sheath cells, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "amygdala: 3.2;cerebral cortex: 4.0;hippocampal formation: 4.5" "HPA040748, HPA042038" Enhanced Supported "Plasma membrane,Cytosol" No No "Cluster 1: T-cells - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 33: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 81: Alveolar cells - Lung function" 7 "Plasma membrane, Cytosol" "HPA040748: , HPA042038: " "unprognostic (9.03e-3)" "potential prognostic unfavorable (9.99e-5)" "unprognostic (1.03e-1)" "unprognostic (8.38e-2)" "unprognostic (1.09e-1)" "unprognostic (4.68e-2)" "unprognostic (2.82e-1)" "unprognostic (8.15e-2)" "unprognostic (2.29e-1)" "unprognostic (1.71e-1)" "unprognostic (7.26e-2)" "unprognostic (1.71e-3)" "unprognostic (1.39e-1)" "unprognostic (4.74e-2)" "unprognostic (4.97e-2)" "unprognostic (2.26e-1)" "unprognostic (2.83e-1)" "unprognostic (3.16e-1)" "unprognostic (1.16e-1)" "unprognostic (1.42e-1)" "unprognostic (5.20e-3)" "unprognostic (2.58e-2)" "unprognostic (5.14e-2)" "unprognostic (5.44e-2)" "unprognostic (1.54e-2)" "unprognostic (3.81e-2)" BFSP2 "CP47, CP49, LIFL-L, phakinin" ENSG00000170819 "Beaded filament structural protein 2" Q13515 3 133400056-133475222 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Eye lens protein" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 5 "Plasma cells: 148.5" "Cell type enhanced" "Detected in many" "leukocyte: 5.4" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 8 "T-reg: 13.4" "Lineage enriched" "Detected in single" 43 "T-cells: 13.4" "Cancer enhanced" "Detected in single" "lymphoma: 1.2" "Minor Salivary Gland - Plasma cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA038464, HPA062959" Enhanced Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 78: Plasma cells - Antibody production & ER-stress response" 60 "Plasma membrane, Cytosol" "HPA038464: , HPA062959: " "unprognostic (2.08e-1)" BGLAP OCN ENSG00000242252 "Bone gamma-carboxyglutamate protein" P02818 1 156242184-156243317 "FDA approved drug targets, Predicted secreted proteins" Biomineralization Hormone "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 12.7;choroid plexus: 6.9;intestine: 17.8" "Cell type enhanced" "Detected in some" "Astrocytes: 2.6;Bergmann glia: 2.0;Brain excitatory neurons: 2.1;Brain inhibitory neurons: 2.1;Choroid plexus epithelial cells: 2.2;Ependymal cells: 1.6;Microglia: 1.5;Oligodendrocyte progenitor cells: 2.7;Oligodendrocytes: 2.9;Other brain neurons: 1.6;Plasma cells: 4.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 17 "NK-cell: 1.8;plasmacytoid DC: 1.6" "Group enriched" "Detected in many" 17 "dendritic cells: 1.6;NK-cells: 1.8" "Cancer enhanced" "Detected in some" "Leukemia: 5.8;Myeloma: 14.4" "Colon - Enteric glia cells" "Region enriched" "Detected in single" 7 "olfactory bulb: 5.3" "Low region specificity" "Detected in all" "Secreted to blood" Hormone NA NA 15500000 1500000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 67: Plasma cells - Plasma cell differentiation" "unprognostic (1.42e-1)" "unprognostic (1.33e-1)" "unprognostic (2.14e-1)" "unprognostic (7.82e-3)" "unprognostic (1.06e-1)" "unprognostic (1.09e-1)" "unprognostic (2.22e-3)" "unprognostic (9.32e-3)" "unprognostic (1.81e-1)" "unprognostic (1.27e-1)" "unprognostic (1.53e-1)" "unprognostic (1.07e-2)" "potential prognostic favorable (1.82e-4)" "unprognostic (4.13e-3)" "unprognostic (3.54e-1)" "unprognostic (1.68e-1)" "unprognostic (2.36e-1)" "unprognostic (1.48e-1)" "unprognostic (8.21e-2)" "unprognostic (3.51e-1)" "unprognostic (2.42e-1)" "unprognostic (7.64e-2)" BGN "DSPG1, SLRR1A" ENSG00000182492 Biglycan P21810 X 153494980-153509546 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Aortic aneurysm, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "blood vessel: 4110.9" "Cell type enhanced" "Detected in many" "Epididymal basal cells: 140.5;Fibroblasts: 213.7;Hepatic stellate cells: 1097.3;Leydig cells: 120.2;Pericytes: 529.2;Peritubular myoid cells: 761.2;Salivary myoepithelial cells: 181.6;Vascular smooth muscle cells: 530.8" "Group enriched" "Detected in some" 8 "fibroblast: 196.0;pericyte: 494.2;vascular associated smooth muscle cell: 261.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 147.9;thyroid cancer: 165.4" "Adipose visceral - Adipose progenitor cells, Adrenal gland - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Pituitary gland - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003157, CAB003678" Enhanced Approved "Endoplasmic reticulum,Golgi apparatus" "Secreted to extracellular matrix" "No annotated function" NA NA 22000000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 34: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 110: Mural cells - ECM organization" 5 "Golgi apparatus" "Endoplasmic reticulum" "CAB003678: , HPA003157: " "unprognostic (2.03e-2)" "unprognostic (3.04e-1)" "unprognostic (3.68e-1)" "unprognostic (2.17e-1)" "potential prognostic unfavorable (8.95e-4)" "unprognostic (1.79e-1)" "unprognostic (1.51e-2)" "potential prognostic unfavorable (8.97e-4)" "unprognostic (9.87e-3)" "unprognostic (6.12e-2)" "unprognostic (4.62e-2)" "unprognostic (1.45e-1)" "unprognostic (1.21e-3)" "unprognostic (1.32e-1)" "unprognostic (5.27e-2)" "unprognostic (1.57e-2)" "unprognostic (4.66e-2)" "unprognostic (2.19e-2)" "unprognostic (1.09e-1)" "unprognostic (3.39e-3)" "unprognostic (6.12e-3)" "unprognostic (9.74e-2)" "unprognostic (1.17e-1)" "unprognostic (1.58e-1)" "unprognostic (3.18e-2)" "unprognostic (1.62e-2)" "potential prognostic unfavorable (7.00e-6)" "unprognostic (7.32e-3)" "unprognostic (3.12e-2)" "unprognostic (2.98e-2)" "unprognostic (2.70e-2)" BHLHA15 "BHLHB8, MIST1" ENSG00000180535 "Basic helix-loop-helix family member a15" Q7RTS1 7 98211439-98215457 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "pancreas: 526.6;salivary gland: 137.4" "Cell type enhanced" "Detected in some" "Breast lactating cells: 43.7;Gastric chief cells: 32.8;Lacrimal acinar cells: 21.7;Pancreatic acinar cells: 150.6;Plasma cells: 51.6;Prostatic glandular cells: 15.4;Salivary acinar cells: 47.2" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Prostate Adenocarcinoma (TCGA): 44.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Myeloma: 56.4" "Kidney - Macrophages, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Stomach - Chief cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB034083, HPA047834" Enhanced Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 8: Pancreas - Proteolysis" "Cluster 29: Forebrain - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 5: Pancreatic acinar cells - Pancreatic exocrine secretion" 21 "Nucleoplasm, Golgi apparatus" "CAB034083: , HPA047834: " "unprognostic (3.36e-2)" "unprognostic (2.87e-2)" "unprognostic (3.14e-1)" "unprognostic (1.21e-2)" "unprognostic (3.19e-2)" "unprognostic (1.36e-1)" "unprognostic (4.80e-3)" "unprognostic (2.74e-1)" "unprognostic (9.86e-2)" "unprognostic (1.56e-2)" "unprognostic (1.11e-1)" "unprognostic (4.02e-2)" "unprognostic (2.41e-2)" "unprognostic (1.71e-1)" "unprognostic (2.41e-2)" "unprognostic (2.17e-1)" "unprognostic (1.25e-2)" "unprognostic (3.10e-1)" "unprognostic (1.18e-2)" "unprognostic (9.58e-2)" "unprognostic (3.40e-1)" "unprognostic (2.26e-1)" "unprognostic (3.15e-1)" "unprognostic (2.68e-1)" "unprognostic (2.93e-1)" "unprognostic (7.40e-2)" BHLHA9 BHLHF42 ENSG00000205899 "Basic helix-loop-helix family member a9" Q7RTU4 17 1270444-1271815 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "brain: 1.3" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 1.0;Other brain neurons: 1.5" "Cell type enhanced" "Detected in some" "lower rhombic lip: 5.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 24: Neurons - Mixed function" "Cluster 98: Neurons - Neurotransmission & signaling" 12 BHLHE22 "Beta3, BHLHB5, CAGL85, TNRC20" ENSG00000180828 "Basic helix-loop-helix family member e22" Q8NFJ8 8 64580365-64583627 "Predicted intracellular proteins, Transcription factors" "Neurogenesis, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 22.8" "Group enriched" "Detected in some" 5 "Retinal amacrine cells: 82.6;Retinal bipolar cells: 41.7" "Cell type enriched" "Detected in many" 7 "cerebellar inhibitory: 185.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Bone cancer: 27.3;Myeloma: 7.6" "Breast - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Spleen - Fibroblasts_1" "Group enriched" "Detected in all" 5 "amygdala: 30.7;cerebellum: 30.7;cerebral cortex: 22.7;hippocampal formation: 46.3;white matter: 13.1" "Group enriched" "Detected in all" 7 "amygdala: 34.9;cerebellum: 15.7;cerebral cortex: 22.4;hippocampal formation: 61.3" "HPA064128, HPA064872, HPA067500" Enhanced Approved "Nucleoplasm,Nuclear speckles,Centrosome,Cytosol" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 29: Forebrain - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "Nucleoplasm, Nuclear speckles" "Centrosome, Cytosol" "HPA064128: , HPA064872: , HPA067500: " "unprognostic (1.40e-3)" "unprognostic (1.40e-1)" "unprognostic (7.80e-3)" "unprognostic (2.77e-2)" "unprognostic (1.10e-1)" "unprognostic (3.18e-3)" "unprognostic (1.26e-1)" "unprognostic (1.69e-3)" "unprognostic (6.88e-2)" BHLHE23 "bA305P22.3, Beta4, BHLHB4" ENSG00000125533 "Basic helix-loop-helix family member e23" Q8NDY6 20 63005927-63007035 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "medulla oblongata: 2.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 13 "Leukemia: 2.1" "Skin - Hair cortex cells, Skin - Inner root sheath cells" "Not detected" "Not detected" "Region enhanced" "Detected in single" "midbrain: 2.3" HPA030575 Uncertain NA NA "Cluster 19: Astrocytes - Mixed function" "Cluster 59: Leukemia - T-cell receptor" 9 "HPA030575: " BHLHE40 "BHLHB2, Clast5, DEC1, SHARP2, STRA13" ENSG00000134107 "Basic helix-loop-helix family member e40" O14503 3 4979437-4985323 "Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial luminal cells: 593.9;Esophageal apical cells: 1200.9;Esophageal suprabasal cells: 739.4;Prostatic hillock cells: 484.0" "Cell type enhanced" "Detected in all" "astrocyte: 147.5;endothelial cell: 208.8;vascular associated smooth muscle cell: 147.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 101.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028922 Uncertain Supported "Nuclear bodies" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 62 "Nuclear bodies" "HPA028922: " "unprognostic (9.05e-2)" "unprognostic (1.22e-1)" "unprognostic (2.56e-1)" "potential prognostic unfavorable (6.37e-4)" "unprognostic (4.65e-2)" "unprognostic (2.31e-1)" "unprognostic (3.52e-3)" "potential prognostic unfavorable (4.93e-4)" "unprognostic (2.24e-1)" "unprognostic (7.00e-2)" "unprognostic (7.33e-2)" "unprognostic (3.52e-2)" "unprognostic (1.04e-1)" "unprognostic (1.64e-1)" "unprognostic (1.13e-2)" "unprognostic (3.18e-2)" "unprognostic (3.77e-3)" "unprognostic (5.57e-3)" "unprognostic (2.00e-1)" "unprognostic (4.07e-3)" "unprognostic (8.08e-2)" "potential prognostic unfavorable (5.16e-4)" "unprognostic (6.23e-2)" "unprognostic (9.03e-2)" "unprognostic (3.56e-1)" "unprognostic (1.34e-2)" "unprognostic (3.53e-1)" "unprognostic (7.40e-2)" "unprognostic (1.89e-1)" "unprognostic (8.75e-2)" "unprognostic (1.07e-1)" BHLHE41 "BHLHB3, DEC2, SHARP-1, SHARP1" ENSG00000123095 "Basic helix-loop-helix family member e41" Q9C0J9 12 26120030-26125037 "Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 113.5;skeletal muscle: 86.6" "Cell type enhanced" "Detected in many" "Epididymal efferent duct absorptive cells: 193.2;Epididymal efferent duct ciliated cells: 156.6;Fallopian secretory cells: 162.2;Hofbauer cells: 191.9;Microglia: 508.8;Müller glia: 295.4;Retinal bipolar cells: 315.9;Retinal horizontal cells: 178.3;Rod photoreceptor cells: 229.8" "Cell type enriched" "Detected in all" 6 "central nervous system macrophage: 556.3" "Cancer enhanced" "Detected in all" "Thyroid Carcinoma (TCGA): 119.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory B-cell: 2.0" "Lineage enriched" "Detected in single" 20 "B-cells: 2.0" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056035, HPA077617" Approved Nucleoplasm,Vesicles NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 15: Kidney cancer - Membrane components" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 3 Nucleoplasm Vesicles "HPA056035: , HPA077617: " "unprognostic (1.01e-3)" "unprognostic (2.78e-3)" "unprognostic (3.41e-1)" "unprognostic (1.96e-1)" "unprognostic (2.19e-2)" "unprognostic (1.07e-1)" "unprognostic (1.51e-1)" "unprognostic (1.74e-2)" "unprognostic (5.70e-2)" "unprognostic (1.15e-1)" "unprognostic (1.12e-2)" "unprognostic (4.95e-3)" "unprognostic (1.46e-1)" "unprognostic (3.80e-2)" "unprognostic (1.91e-1)" "unprognostic (9.08e-2)" "unprognostic (1.76e-1)" "unprognostic (1.56e-2)" "unprognostic (1.85e-2)" "unprognostic (4.80e-2)" "unprognostic (1.02e-1)" "unprognostic (4.64e-2)" "unprognostic (2.79e-1)" "unprognostic (3.45e-2)" "unprognostic (1.89e-1)" "unprognostic (3.75e-1)" "unprognostic (1.37e-1)" "unprognostic (3.28e-2)" "unprognostic (1.16e-1)" "unprognostic (7.29e-3)" "unprognostic (2.90e-1)" BHMT BHMT1 ENSG00000145692 "Betaine--homocysteine S-methyltransferase" Q93088 5 79111809-79132288 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 80 "kidney: 727.4;liver: 1067.7" "Cell type enhanced" "Detected in many" "Epididymal efferent duct absorptive cells: 77.5;Hepatocytes: 934.5;Proximal tubule cells: 420.8;Urothelial cells: 178.9" "Cell type enriched" "Detected in many" 19 "hippocampal CA4: 58.5" "Group enriched" "Detected in many" 5 "Kidney Renal Clear Cell Carcinoma (TCGA): 160.6;Kidney Renal Papillary Cell Carcinoma (TCGA): 44.7;Liver Hepatocellular Carcinoma (TCGA): 167.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 4.2;Kidney cancer: 1.9" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA038285, HPA058310" Enhanced Approved Cytosol No NA 15000000 "Cluster 16: Liver & Kidney - Metabolism" "Cluster 51: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 88: Proximal tubular cells - Transmembrane transport" Cytosol "HPA038285: , HPA058310: " "unprognostic (1.61e-1)" "unprognostic (2.06e-2)" "validated prognostic favorable (3.94e-8)" "validated prognostic favorable (2.11e-4)" "unprognostic (3.12e-2)" "potential prognostic favorable (8.19e-4)" "unprognostic (1.31e-3)" "unprognostic (9.17e-2)" "unprognostic (3.31e-1)" BHMT2 ENSG00000132840 "Betaine--homocysteine S-methyltransferase 2" Q9H2M3 5 79069767-79090069 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "kidney: 310.9;liver: 401.8" "Cell type enhanced" "Detected in many" "Adipocytes: 113.8;Epididymal efferent duct absorptive cells: 162.6;Hepatocytes: 569.6;Loop of henle epithelial cells: 86.1;Pituicytes/FSCs: 90.0;Proximal tubule cells: 315.7;Renal connecting tubule cells: 89.9;Retinal pigment epithelial cells: 144.9" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 54.3;fibroblast: 105.8" "Group enriched" "Detected in many" 11 "Kidney Renal Clear Cell Carcinoma (TCGA): 142.5;Kidney Renal Papillary Cell Carcinoma (TCGA): 92.0;Liver Hepatocellular Carcinoma (TCGA): 160.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 9 "Adrenocortical cancer: 94.2;Kidney cancer: 68.7;liver cancer: 44.2" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Smooth muscle cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA044573 Enhanced NA NA 4100000 "Cluster 16: Liver & Kidney - Metabolism" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 15: Kidney cancer - Membrane components" "Cluster 88: Proximal tubular cells - Transmembrane transport" 1 "HPA044573: " "unprognostic (1.24e-2)" "unprognostic (7.85e-2)" "unprognostic (5.10e-3)" "unprognostic (6.87e-2)" "unprognostic (9.36e-2)" "unprognostic (9.10e-3)" "unprognostic (3.85e-2)" "unprognostic (3.70e-2)" "potential prognostic favorable (4.10e-4)" "unprognostic (9.85e-3)" "unprognostic (5.44e-2)" "unprognostic (7.38e-3)" "unprognostic (2.30e-3)" "unprognostic (1.01e-1)" "unprognostic (2.46e-1)" "unprognostic (9.51e-2)" "unprognostic (6.39e-2)" "unprognostic (6.56e-3)" "unprognostic (2.06e-1)" "unprognostic (1.17e-2)" "unprognostic (3.51e-1)" "unprognostic (3.97e-2)" "unprognostic (6.03e-3)" "unprognostic (2.78e-1)" "unprognostic (2.66e-2)" "unprognostic (1.33e-1)" "unprognostic (1.67e-1)" "unprognostic (2.63e-2)" BICC1 ENSG00000122870 "BicC family RNA binding protein 1" Q9H694 10 58512872-58831435 "Disease related genes, Predicted intracellular proteins" "Developmental protein, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 26.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 1483.0;Distal convoluted tubule cells: 1678.4;Endometrial ciliated cells: 672.8;Fibro-adipogenic progenitors: 1299.2;Leydig cells: 770.2;Loop of henle epithelial cells: 1486.4;Mesothelial cells: 933.6;Myonuclei: 935.6;Pancreatic duct cells: 1492.1;Proximal tubule cells: 1981.2;Renal collecting duct principal cells: 1044.1;Renal connecting tubule cells: 2040.2" "Cell type enriched" "Detected in all" 5 "fibroblast: 1315.7" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 33.9;Kidney Renal Papillary Cell Carcinoma (TCGA): 64.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 10 "basophil: 6.2" "Lineage enriched" "Detected in single" 10 "granulocytes: 6.2" "Cancer enhanced" "Detected in many" "Kidney cancer: 68.3" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Lung - Fibroblasts_2, Prostate - Fibroblasts, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070797 Approved Centrosome,Cytosol NA NA "Cluster 41: Basophils - Unknown function" "Cluster 72: Kidney - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 88: Proximal tubular cells - Transmembrane transport" Cytosol Centrosome "HPA070797: " "unprognostic (8.93e-2)" "unprognostic (1.73e-1)" "unprognostic (2.58e-1)" "unprognostic (6.92e-3)" "unprognostic (1.05e-1)" "unprognostic (2.07e-1)" "unprognostic (3.73e-3)" "unprognostic (1.49e-2)" "unprognostic (7.07e-2)" "unprognostic (9.56e-2)" "potential prognostic favorable (4.08e-5)" "unprognostic (9.46e-2)" "unprognostic (1.74e-1)" "unprognostic (2.96e-3)" "unprognostic (1.47e-1)" "unprognostic (1.18e-2)" "unprognostic (1.39e-1)" "unprognostic (1.06e-1)" "unprognostic (2.88e-1)" "potential prognostic unfavorable (5.86e-4)" "unprognostic (5.94e-2)" "unprognostic (2.01e-3)" "unprognostic (5.20e-2)" "unprognostic (8.93e-2)" "unprognostic (1.45e-1)" "unprognostic (8.77e-3)" "unprognostic (2.10e-1)" "unprognostic (1.56e-3)" "unprognostic (2.64e-2)" "unprognostic (4.64e-2)" "unprognostic (7.55e-2)" BICD1 ENSG00000151746 "BICD cargo adaptor 1" Q96G01 12 32106835-32383633 "Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 521.2;Lactotrophs: 599.9;Podocytes: 499.2;Renal connecting tubule cells: 513.8;Somatotrophs: 525.7;Thyrotrophs: 520.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 80.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041309 Approved Uncertain Vesicles NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 65: Brain - Transcription" "Cluster 2: Neurons - Nucleosome" "Cluster 38: Non-specific - Transcription" "Cluster 55: Myocytes - Oxidative muscle function" 12 Vesicles "HPA041309: " "unprognostic (2.27e-1)" "unprognostic (6.99e-2)" "unprognostic (1.20e-3)" "unprognostic (3.63e-2)" "unprognostic (3.46e-2)" "unprognostic (3.46e-1)" "unprognostic (4.01e-1)" "unprognostic (5.30e-3)" "unprognostic (3.68e-2)" "unprognostic (3.02e-3)" "potential prognostic unfavorable (5.00e-4)" "unprognostic (5.00e-1)" "potential prognostic unfavorable (3.28e-5)" "potential prognostic unfavorable (5.57e-5)" "unprognostic (3.84e-2)" "unprognostic (1.36e-2)" "potential prognostic unfavorable (1.23e-4)" "unprognostic (2.28e-1)" "unprognostic (9.41e-2)" "unprognostic (2.98e-1)" "unprognostic (2.80e-1)" "unprognostic (2.90e-2)" "unprognostic (1.70e-2)" "unprognostic (4.61e-2)" "unprognostic (1.32e-1)" "unprognostic (1.75e-2)" "unprognostic (4.13e-1)" "unprognostic (4.51e-1)" "unprognostic (1.75e-1)" "unprognostic (1.81e-1)" "unprognostic (4.94e-2)" BICD2 KIAA0699 ENSG00000185963 "BICD cargo adaptor 2" Q8TD16 9 92711363-92764833 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "mRNA transport, Protein transport, Translocation, Transport" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 60.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 142.9;Esophageal apical cells: 124.8;Esophageal suprabasal cells: 113.7;Neutrophil progenitors: 105.7;Neutrophils: 167.5;Ocular epithelial cells: 109.4;Platelets: 177.8;Suprabasal keratinocytes: 181.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023013, HPA024452" Enhanced Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 58: Skin - Keratinization" "Cluster 30: White matter - Myelination" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 46 "Golgi apparatus, Plasma membrane, Cytosol" "HPA023013: , HPA024452: " "unprognostic (5.08e-2)" "unprognostic (5.98e-3)" "unprognostic (1.21e-1)" "unprognostic (2.35e-1)" "unprognostic (3.19e-2)" "unprognostic (1.99e-2)" "unprognostic (1.79e-1)" "potential prognostic favorable (6.09e-5)" "unprognostic (2.62e-1)" "unprognostic (1.78e-1)" "validated prognostic favorable (4.26e-5)" "validated prognostic favorable (2.43e-4)" "unprognostic (7.38e-2)" "unprognostic (2.69e-2)" "unprognostic (1.00e-2)" "unprognostic (1.43e-1)" "unprognostic (2.49e-1)" "unprognostic (7.97e-2)" "unprognostic (1.25e-1)" "unprognostic (1.80e-2)" "unprognostic (5.30e-2)" "unprognostic (1.37e-1)" "unprognostic (1.28e-3)" "unprognostic (1.93e-1)" "unprognostic (2.45e-1)" "unprognostic (3.80e-3)" "unprognostic (1.29e-1)" "unprognostic (5.87e-2)" "unprognostic (1.59e-1)" "unprognostic (1.22e-1)" "unprognostic (2.41e-2)" BICDL1 "BICDR-1, CCDC64, FLJ26450" ENSG00000135127 "BICD family like cargo adaptor 1" Q6ZP65 12 119989236-120094494 "Predicted intracellular proteins" "Neurogenesis, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 112.8;pituitary gland: 63.8" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 544.4;Distal convoluted tubule cells: 400.3;Epicardial cells: 307.0;Gonadotrophs: 238.8;Loop of henle epithelial cells: 563.6;Mesothelial cells: 242.8;Proximal tubule cells: 404.2;Retinal ganglion cells: 332.2;Rod photoreceptor cells: 531.6;Somatotrophs: 468.4;T-cells: 257.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Renal Papillary Cell Carcinoma (TCGA): 96.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - T-cells, Adipose visceral - Mesothelial cells, Pituitary gland - Somatotropes, Spleen - T-cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061116 Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 72: Kidney - Transmembrane transport" "Cluster 1: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 9: T-cells - Adaptive immunity: Regulation" "Nucleoplasm, Cytosol" Vesicles "HPA061116: " "unprognostic (1.67e-1)" "unprognostic (1.61e-1)" "unprognostic (4.88e-2)" "unprognostic (7.18e-3)" "unprognostic (9.83e-2)" "potential prognostic unfavorable (2.27e-4)" "unprognostic (5.05e-2)" "unprognostic (1.35e-3)" "unprognostic (3.30e-2)" "unprognostic (2.67e-3)" "unprognostic (3.81e-2)" "potential prognostic favorable (3.10e-4)" "unprognostic (8.05e-3)" "unprognostic (5.95e-2)" "unprognostic (3.39e-2)" "unprognostic (1.78e-1)" "unprognostic (2.96e-1)" "unprognostic (5.37e-2)" "unprognostic (2.36e-2)" "unprognostic (1.65e-3)" "unprognostic (2.51e-1)" "unprognostic (2.82e-1)" "unprognostic (1.24e-1)" "unprognostic (1.86e-1)" "unprognostic (9.68e-2)" "potential prognostic favorable (9.31e-5)" "unprognostic (2.03e-1)" "unprognostic (3.25e-1)" "unprognostic (5.59e-2)" BICDL2 CCDC64B ENSG00000162069 "BICD family like cargo adaptor 2" A1A5D9 16 3027682-3036944 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 101.5;pancreas: 123.7" "Cell type enriched" "Detected in many" 4 "Esophageal apical cells: 1246.7" "Cell type enhanced" "Detected in many" "lower rhombic lip: 16.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Colon - Colon enterocytes, Liver - Cholangiocytes, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Region enhanced" "Detected in some" "basal ganglia: 3.7" HPA043251 Approved Approved "Intermediate filaments,Actin filaments,Cytosol" No NA "Cluster 60: Stomach - Digestion" "Cluster 24: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 4 "Intermediate filaments, Actin filaments, Cytosol" "HPA043251: " "potential prognostic favorable (8.48e-4)" "unprognostic (1.30e-1)" "unprognostic (1.77e-1)" "unprognostic (1.13e-1)" "unprognostic (1.31e-1)" "unprognostic (1.59e-2)" "unprognostic (1.45e-3)" "unprognostic (2.99e-2)" "unprognostic (8.00e-2)" "unprognostic (9.92e-2)" "unprognostic (1.53e-1)" "unprognostic (5.92e-2)" "unprognostic (1.03e-1)" "unprognostic (3.40e-2)" "unprognostic (8.70e-2)" "unprognostic (1.20e-3)" "unprognostic (2.37e-1)" "unprognostic (1.90e-2)" "unprognostic (2.33e-1)" "unprognostic (1.36e-1)" "unprognostic (7.16e-2)" "unprognostic (1.55e-2)" "unprognostic (2.09e-1)" "unprognostic (2.85e-2)" "unprognostic (1.62e-1)" "unprognostic (1.25e-1)" "unprognostic (3.96e-2)" BICRA "GLTSCR1, SMARCK1" ENSG00000063169 "BRD4 interacting chromatin remodeling complex associated protein" Q9NZM4 19 47608196-47703277 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Hematopoietic stem cells: 1.9;Mesothelial cells: 1.1;Salivary ionocytes: 1.1" "Low cell type specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056211 Approved Approved Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 4: Non-specific - Transcription" "Cluster 9: T-cells - Adaptive immunity: Regulation" 21 Nucleoplasm "HPA056211: " "potential prognostic favorable (4.63e-4)" "unprognostic (1.68e-1)" "unprognostic (8.63e-3)" "unprognostic (2.06e-1)" "unprognostic (1.91e-1)" "unprognostic (1.76e-1)" "unprognostic (3.29e-1)" "unprognostic (2.78e-2)" "unprognostic (9.33e-2)" "unprognostic (1.41e-2)" "unprognostic (3.50e-1)" "unprognostic (1.03e-1)" "unprognostic (2.36e-1)" "unprognostic (1.43e-2)" "unprognostic (2.27e-1)" "unprognostic (1.61e-1)" "unprognostic (4.12e-2)" "unprognostic (1.08e-2)" "unprognostic (1.16e-1)" "unprognostic (2.81e-2)" "unprognostic (5.58e-2)" "unprognostic (5.18e-2)" "unprognostic (2.32e-1)" "potential prognostic favorable (3.38e-4)" "unprognostic (4.84e-2)" "unprognostic (8.81e-2)" "unprognostic (2.67e-1)" "unprognostic (2.37e-2)" "unprognostic (6.03e-2)" BICRAL "GLTSCR1L, KIAA0240, SMARCK2" ENSG00000112624 "BICRA like chromatin remodeling complex associated protein" Q6AI39 6 42746958-42868558 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Myonuclei: 359.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029390, HPA029391" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 61: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 24: Neutrophils - Innate immunity signal integration" 16 Nucleoplasm Cytosol "HPA029390: , HPA029391: " "unprognostic (1.27e-1)" "unprognostic (2.10e-1)" "unprognostic (1.03e-1)" "unprognostic (3.28e-1)" "unprognostic (7.85e-2)" "unprognostic (9.87e-2)" "unprognostic (4.69e-2)" "unprognostic (1.23e-3)" "unprognostic (4.23e-2)" "validated prognostic favorable (1.10e-6)" "validated prognostic favorable (5.97e-5)" "unprognostic (7.36e-2)" "unprognostic (9.84e-2)" "unprognostic (5.54e-2)" "unprognostic (1.37e-1)" "unprognostic (6.32e-2)" "unprognostic (7.10e-2)" "unprognostic (7.80e-2)" "unprognostic (3.83e-1)" "unprognostic (1.73e-1)" "unprognostic (8.81e-2)" "unprognostic (1.53e-1)" "unprognostic (2.04e-3)" "unprognostic (3.05e-1)" "unprognostic (1.53e-1)" "unprognostic (2.36e-1)" "unprognostic (6.47e-2)" "unprognostic (3.67e-2)" "unprognostic (1.68e-1)" BID ENSG00000015475 "BH3 interacting domain death agonist" P55957 22 17734138-17774770 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 97.6" "Cell type enhanced" "Detected in many" "cDC: 454.8;monocytes: 343.1;Neutrophil progenitors: 175.0;Neutrophils: 1074.0;pDCs: 260.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 6 "dendritic cells: 346.3;granulocytes: 930.7;monocytes: 990.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000722, CAB003771" Enhanced Supported Mitochondria,Cytosol NA NA 840000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 24: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 32 Cytosol Mitochondria "CAB003771: , HPA000722: " "unprognostic (2.48e-1)" "unprognostic (3.36e-2)" "unprognostic (1.93e-2)" "unprognostic (7.99e-3)" "unprognostic (4.10e-2)" "unprognostic (4.38e-2)" "unprognostic (1.42e-2)" "unprognostic (1.95e-2)" "unprognostic (2.04e-2)" "unprognostic (1.03e-1)" "potential prognostic unfavorable (3.51e-5)" "unprognostic (1.21e-2)" "potential prognostic unfavorable (2.82e-4)" "unprognostic (4.36e-3)" "unprognostic (1.29e-2)" "unprognostic (1.85e-3)" "unprognostic (6.44e-2)" "unprognostic (7.86e-2)" "unprognostic (6.07e-2)" "unprognostic (3.85e-1)" "unprognostic (1.59e-1)" "unprognostic (3.76e-3)" "unprognostic (2.00e-2)" "unprognostic (3.03e-1)" "unprognostic (1.93e-2)" "unprognostic (5.77e-2)" "unprognostic (4.52e-3)" "unprognostic (9.85e-3)" "unprognostic (9.69e-2)" "unprognostic (2.26e-2)" "unprognostic (8.66e-2)" BIK NBK ENSG00000100290 "BCL2 interacting killer" Q13323 22 43110750-43129712 "Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 16.9" "Cell type enhanced" "Detected in many" "Endometrial secretory cells: 123.5;Esophageal apical cells: 299.2;Gastric progenitor cells: 96.1;Oocytes: 478.9;Tuft cells: 472.7" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 2.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 73.0;plasmacytoid DC: 58.7" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Bile duct cancer: 57.5" "Breast - Breast glandular cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells" "Not detected" "Not detected" HPA051360 Approved NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 15: Non-specific - Transcription" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 95: Tuft cells - Chemosensory signaling" 91 "HPA051360: " "unprognostic (8.58e-3)" "potential prognostic unfavorable (6.00e-4)" "unprognostic (1.90e-2)" "unprognostic (2.39e-1)" "unprognostic (5.81e-2)" "unprognostic (1.87e-2)" "unprognostic (1.37e-3)" "unprognostic (2.30e-1)" "unprognostic (5.05e-2)" "unprognostic (1.89e-1)" "unprognostic (2.29e-2)" "unprognostic (2.76e-3)" "unprognostic (3.18e-2)" "unprognostic (6.37e-2)" "unprognostic (7.47e-2)" "unprognostic (1.36e-2)" "unprognostic (2.67e-1)" "unprognostic (2.63e-3)" "unprognostic (1.94e-1)" "unprognostic (7.71e-2)" "unprognostic (1.77e-1)" "unprognostic (1.32e-2)" "unprognostic (1.14e-1)" "unprognostic (4.10e-2)" "unprognostic (1.90e-1)" "unprognostic (1.19e-2)" "unprognostic (2.71e-1)" BIN1 "AMPH2, AMPHL, SH3P9" ENSG00000136717 "Bridging integrator 1" O00499 2 127048027-127107288 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Endocytosis, Host-virus interaction" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "skeletal muscle: 1986.0;tongue: 751.1" "Cell type enhanced" "Detected in many" "Hofbauer cells: 385.3;Microglia: 235.2;Myonuclei: 181.9;Oligodendrocytes: 299.9;Smooth muscle cells: 159.7;Thymic myoid cells: 988.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Renal Papillary Cell Carcinoma (TCGA): 183.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "gdT-cell: 187.0;MAIT T-cell: 164.2;memory B-cell: 166.4;memory CD4 T-cell: 192.6;memory CD8 T-cell: 187.4;naive B-cell: 181.9;naive CD4 T-cell: 177.5;naive CD8 T-cell: 171.5;NK-cell: 179.5;T-reg: 250.4" "Group enriched" "Detected in all" 9 "B-cells: 181.9;NK-cells: 179.5;T-cells: 250.4" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001945, HPA003894, HPA005437" Enhanced Supported Cytosol NA NA 810000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 11: White matter - Signal transduction" "Cluster 18: Liver cancer - Metabolism" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 46 Cytosol "CAB001945: , HPA003894: , HPA005437: " "unprognostic (1.71e-1)" "unprognostic (8.95e-2)" "unprognostic (2.00e-2)" "unprognostic (1.39e-1)" "unprognostic (1.66e-1)" "unprognostic (9.76e-3)" "unprognostic (5.90e-2)" "potential prognostic favorable (4.60e-4)" "unprognostic (4.63e-2)" "unprognostic (4.32e-2)" "unprognostic (1.22e-3)" "unprognostic (5.52e-1)" "potential prognostic favorable (3.60e-4)" "unprognostic (4.16e-3)" "potential prognostic unfavorable (4.11e-4)" "unprognostic (3.87e-2)" "unprognostic (1.19e-2)" "unprognostic (2.60e-1)" "unprognostic (7.09e-2)" "unprognostic (8.78e-2)" "unprognostic (3.37e-1)" "unprognostic (1.47e-2)" "unprognostic (4.00e-1)" "unprognostic (3.90e-1)" "unprognostic (2.28e-2)" "unprognostic (3.33e-2)" "unprognostic (2.34e-1)" "unprognostic (1.77e-2)" "unprognostic (2.90e-1)" "unprognostic (1.03e-3)" "unprognostic (9.28e-2)" BIN2 BRAP-1 ENSG00000110934 "Bridging integrator 2" Q9UBW5 12 51281038-51324668 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 95.7;lymphoid tissue: 48.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 153.0;Extravillous trophoblasts: 293.3;Megakaryocytes: 531.6;Microglia: 175.4;monocytes: 163.2;Neutrophil progenitors: 389.9;Neutrophils: 547.9;NK-cells: 339.3;Platelets: 1232.5;Syncytiotrophoblasts: 191.6;T-cells: 172.2" "Group enriched" "Detected in some" 98 "central nervous system macrophage: 205.0;leukocyte: 201.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Leukemia: 55.4;Myeloma: 48.7" "Adrenal gland - Macrophages, Lung - Neutrophils_2, Spleen - Neutrophils_2, Testis - Early spermatids, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038666, HPA038667" Enhanced Enhanced "Plasma membrane" NA NA 20000000 "Cluster 35: Neutrophils - Protein binding" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 4 "Plasma membrane" "HPA038666: , HPA038667: " "unprognostic (1.16e-1)" "unprognostic (2.38e-2)" "unprognostic (2.11e-3)" "unprognostic (1.29e-3)" "unprognostic (8.32e-2)" "unprognostic (3.12e-1)" "unprognostic (1.52e-1)" "unprognostic (6.28e-2)" "unprognostic (5.63e-3)" "unprognostic (2.83e-1)" "unprognostic (1.68e-1)" "unprognostic (1.63e-2)" "unprognostic (1.70e-2)" "unprognostic (1.33e-1)" "unprognostic (4.13e-2)" "unprognostic (4.92e-3)" "unprognostic (1.97e-1)" "unprognostic (2.23e-2)" "unprognostic (2.98e-1)" "unprognostic (1.87e-1)" "unprognostic (9.30e-2)" "unprognostic (8.16e-2)" "unprognostic (9.34e-2)" "unprognostic (1.34e-1)" "unprognostic (1.60e-2)" "unprognostic (1.63e-1)" "unprognostic (2.45e-2)" "unprognostic (3.18e-1)" "unprognostic (4.50e-2)" "unprognostic (3.65e-2)" "unprognostic (1.75e-1)" BIN3 ENSG00000147439 "Bridging integrator 3" Q9NQY0 8 22620418-22669148 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Septation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 198.1;Neutrophil progenitors: 186.4;Neutrophils: 362.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "skin cancer: 84.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023769 Approved NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 15: Bone marrow - Innate immune response" "Cluster 23: Choroid plexus - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 17 "HPA023769: " "unprognostic (3.49e-1)" "unprognostic (4.89e-2)" "potential prognostic favorable (5.13e-7)" "unprognostic (4.05e-2)" "unprognostic (2.14e-3)" "unprognostic (9.15e-2)" "potential prognostic unfavorable (2.82e-4)" "potential prognostic favorable (9.56e-4)" "unprognostic (2.80e-1)" "unprognostic (2.07e-2)" "potential prognostic unfavorable (9.07e-4)" "unprognostic (1.27e-1)" "unprognostic (2.51e-3)" "unprognostic (1.09e-2)" "unprognostic (8.16e-2)" "unprognostic (1.68e-1)" "unprognostic (1.47e-1)" "unprognostic (3.39e-3)" "unprognostic (1.88e-1)" "unprognostic (2.04e-1)" "unprognostic (3.27e-2)" "unprognostic (2.07e-2)" "unprognostic (1.70e-1)" "unprognostic (1.90e-1)" "unprognostic (1.74e-1)" "unprognostic (2.25e-1)" "unprognostic (9.61e-2)" "unprognostic (9.70e-3)" "unprognostic (1.66e-1)" "unprognostic (2.93e-1)" "unprognostic (3.15e-2)" BIRC2 "API1, c-IAP1, cIAP1, hiap-2, MIHB, RNF48" ENSG00000110330 "Baculoviral IAP repeat containing 2" Q13490 11 102347211-102378670 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 242.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in all" 4 "Adrenocortical cancer: 319.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005513, CAB020661" Supported Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 55: Non-specific - Transcription" "Cluster 72: Neuronal - Signal transduction" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 131 "Nucleoli fibrillar center, Cytosol" Nucleoplasm "CAB020661: , HPA005513: " "unprognostic (1.60e-1)" "unprognostic (7.44e-2)" "unprognostic (2.34e-1)" "unprognostic (1.43e-1)" "unprognostic (2.83e-1)" "unprognostic (5.18e-2)" "unprognostic (1.78e-1)" "unprognostic (1.96e-1)" "unprognostic (1.52e-1)" "unprognostic (4.57e-2)" "unprognostic (3.28e-3)" "unprognostic (9.14e-3)" "unprognostic (9.06e-2)" "unprognostic (6.81e-2)" "unprognostic (2.85e-1)" "potential prognostic unfavorable (3.78e-5)" "unprognostic (1.93e-2)" "unprognostic (3.50e-1)" "unprognostic (3.01e-2)" "unprognostic (4.83e-1)" "unprognostic (1.40e-1)" "unprognostic (1.79e-2)" "potential prognostic unfavorable (7.24e-5)" "unprognostic (2.91e-2)" "unprognostic (5.09e-3)" "unprognostic (2.93e-2)" "unprognostic (1.86e-2)" "unprognostic (8.57e-2)" "unprognostic (2.89e-1)" "unprognostic (3.09e-1)" "unprognostic (1.25e-2)" BIRC3 "API2, c-IAP2, cIAP2, hiap-1, MALT2, MIHC, RNF49" ENSG00000023445 "Baculoviral IAP repeat containing 3" Q13489 11 102317450-102339403 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 83.8;lymphoid tissue: 132.2" "Cell type enhanced" "Detected in many" "cDC: 836.4;Enterocytes: 1048.9;Fallopian secretory cells: 529.9;Mast cells: 868.5;Pancreatic duct cells: 446.2;Plasma cells: 500.4" "Cell type enhanced" "Detected in many" "endothelial cell: 44.7;leukocyte: 63.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "memory B-cell: 210.0;naive B-cell: 160.8" "Group enriched" "Detected in all" 13 "B-cells: 210.0;T-cells: 83.8" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 295.5" "Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002317 Enhanced Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 23: Choroid plexus - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 82: Dendritic cells - Antigen presentation" 83 "Nucleoplasm, Cytosol" "HPA002317: " "unprognostic (3.73e-2)" "unprognostic (2.19e-3)" "unprognostic (1.82e-2)" "unprognostic (2.64e-1)" "unprognostic (3.90e-1)" "unprognostic (1.36e-1)" "unprognostic (1.58e-3)" "potential prognostic unfavorable (8.96e-6)" "unprognostic (3.60e-2)" "unprognostic (9.88e-2)" "unprognostic (4.08e-2)" "unprognostic (3.09e-1)" "potential prognostic unfavorable (1.96e-4)" "unprognostic (2.53e-1)" "unprognostic (3.54e-2)" "potential prognostic unfavorable (1.05e-4)" "unprognostic (4.43e-2)" "unprognostic (3.26e-2)" "unprognostic (3.99e-1)" "unprognostic (1.75e-2)" "unprognostic (2.47e-2)" "unprognostic (3.55e-3)" "unprognostic (7.43e-3)" "unprognostic (4.57e-1)" "unprognostic (2.15e-3)" "unprognostic (2.78e-2)" "unprognostic (1.06e-1)" "unprognostic (7.63e-2)" "unprognostic (2.42e-3)" "unprognostic (1.74e-1)" "unprognostic (1.15e-1)" BIRC5 "API4, EPR-1, survivin" ENSG00000089685 "Baculoviral IAP repeat containing 5" O15392 17 78214186-78225636 "Cancer-related genes, Essential proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Chromosome partition, Host-virus interaction, Mitosis, Transcription, Transcription regulation" "Protease inhibitor, Repressor, Thiol protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 35.8;lymphoid tissue: 38.1;testis: 18.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 83.9;Differentiating spermatogonia: 100.9;Early primary spermatocytes: 111.0;Early spermatids: 75.5;Enteric transient amplifying cells: 105.2;Erythrocyte progenitors: 154.8;Esophageal basal cells: 169.3;Extravillous trophoblasts: 178.1;Gastric progenitor cells: 115.4;Hofbauer cells: 76.9;Late primary spermatocytes: 284.0;Late spermatids: 95.3;Megakaryocyte progenitors: 121.8;Megakaryocytes: 92.7;Migrating cytotrophoblasts: 140.7;Monocyte progenitors: 135.3;Oocytes: 124.3" "Cell type enhanced" "Detected in single" "upper rhombic lip: 1.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "T-reg: 14.1" "Lineage enriched" "Detected in many" 6 "T-cells: 14.1" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA002830, CAB004270" Enhanced Supported "Cytokinetic bridge" Yes Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 11: White matter - Signal transduction" "Cluster 27: Breast cancer - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 57 "Cytokinetic bridge" "CAB004270: , HPA002830: " "unprognostic (1.18e-2)" "unprognostic (3.64e-2)" "unprognostic (1.37e-1)" "unprognostic (2.55e-1)" "unprognostic (1.82e-2)" "unprognostic (7.15e-2)" "unprognostic (2.36e-1)" "unprognostic (1.03e-1)" "unprognostic (2.26e-2)" "potential prognostic unfavorable (2.00e-5)" "validated prognostic unfavorable (3.12e-10)" "validated prognostic unfavorable (1.21e-7)" "potential prognostic unfavorable (6.21e-12)" "validated prognostic unfavorable (8.71e-6)" "validated prognostic unfavorable (4.42e-10)" "validated prognostic unfavorable (4.12e-5)" "validated prognostic unfavorable (2.52e-4)" "unprognostic (1.10e-1)" "unprognostic (9.49e-3)" "unprognostic (5.22e-2)" "unprognostic (1.04e-3)" "unprognostic (3.02e-3)" "unprognostic (2.80e-2)" "unprognostic (6.62e-2)" "unprognostic (1.35e-1)" "unprognostic (3.72e-3)" "unprognostic (5.51e-2)" "unprognostic (1.57e-2)" "unprognostic (1.74e-1)" "unprognostic (2.61e-2)" "unprognostic (2.84e-1)" BIRC6 BRUCE ENSG00000115760 "Baculoviral IAP repeat containing 6" Q9NR09 2 32357023-32619571 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Protease inhibitor, Thiol protease inhibitor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 9.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 9.7" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA074409, HPA074738" Approved Supported "Golgi apparatus,Vesicles,Mitotic spindle" Yes No "Cluster 24: Non-specific - Transcription" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 7: Non-specific - Transcription" 45 "Golgi apparatus, Vesicles" "Mitotic spindle" "HPA074409: , HPA074738: " "unprognostic (1.98e-1)" "unprognostic (6.23e-2)" "unprognostic (1.14e-1)" "unprognostic (3.23e-2)" "unprognostic (6.53e-2)" "unprognostic (2.28e-1)" "unprognostic (1.16e-2)" "unprognostic (5.56e-3)" "unprognostic (4.31e-2)" "unprognostic (3.19e-3)" "potential prognostic favorable (1.98e-6)" "unprognostic (6.24e-3)" "unprognostic (1.69e-1)" "unprognostic (2.77e-1)" "unprognostic (1.47e-1)" "unprognostic (2.22e-1)" "unprognostic (8.68e-3)" "unprognostic (2.77e-2)" "unprognostic (3.61e-1)" "unprognostic (1.79e-2)" "unprognostic (5.70e-2)" "unprognostic (3.60e-2)" "potential prognostic unfavorable (6.11e-4)" "unprognostic (1.17e-1)" "unprognostic (7.54e-3)" "potential prognostic favorable (3.11e-4)" "unprognostic (1.55e-1)" "unprognostic (3.19e-1)" "unprognostic (3.08e-1)" "unprognostic (1.43e-2)" "unprognostic (1.03e-1)" BIRC7 "KIAP, ML-IAP, mliap, RNF50" ENSG00000101197 "Baculoviral IAP repeat containing 7" Q96CA5 20 63235883-63240495 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Protease inhibitor, Thiol protease inhibitor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 6.1" "Cell type enhanced" "Detected in some" "Epididymal efferent duct absorptive cells: 55.6;Extravillous trophoblasts: 23.8;Hofbauer cells: 172.5;Melanocytes: 36.9;Migrating cytotrophoblasts: 88.9;Müller glia: 53.0" "Cell type enhanced" "Detected in some" "astrocyte: 2.4;central nervous system macrophage: 1.2" "Cancer enriched" "Detected in many" 8 "Skin Cutaneous Melanoma (TCGA): 144.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "skin cancer: 79.9" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA047850, HPA061283" Enhanced Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 39: Astrocytes - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 11: Muller glia cells - Retinal homeostasis" 45 Nucleoplasm "Centrosome, Cytosol" "HPA047850: , HPA061283: " "unprognostic (7.51e-2)" "potential prognostic favorable (7.14e-4)" "unprognostic (1.85e-3)" "unprognostic (2.88e-1)" "unprognostic (2.47e-2)" "unprognostic (8.65e-2)" "unprognostic (5.29e-2)" "unprognostic (3.46e-3)" "unprognostic (1.15e-1)" "unprognostic (4.85e-2)" "unprognostic (5.77e-2)" "unprognostic (1.77e-1)" "unprognostic (3.01e-2)" "unprognostic (6.64e-3)" "unprognostic (2.10e-1)" "unprognostic (1.38e-2)" "unprognostic (8.53e-3)" "unprognostic (7.75e-2)" "unprognostic (2.49e-2)" "unprognostic (4.67e-3)" BIVM FLJ20159 ENSG00000134897 "Basic, immunoglobulin-like variable motif containing" Q86UB2 13 102799119-102841533 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 24 "Astrocytes: 50.6;Bergmann glia: 58.0;Brain excitatory neurons: 85.3;Brain inhibitory neurons: 95.9;Choroid plexus epithelial cells: 61.0;Ependymal cells: 32.7;Microglia: 24.9;Oligodendrocyte progenitor cells: 80.8;Oligodendrocytes: 69.4;Other brain neurons: 66.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 7.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050126 Approved Supported Nucleoplasm NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 15: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 22: Non-specific - Basic cellular functions" 8 Nucleoplasm "HPA050126: " "unprognostic (7.62e-2)" "unprognostic (1.13e-1)" "unprognostic (5.78e-2)" "unprognostic (1.01e-1)" "unprognostic (1.07e-1)" "unprognostic (2.46e-1)" "unprognostic (8.99e-2)" "unprognostic (6.46e-3)" "unprognostic (1.16e-2)" "unprognostic (1.16e-1)" "potential prognostic favorable (1.66e-4)" "unprognostic (9.39e-2)" "unprognostic (1.24e-3)" "unprognostic (1.76e-1)" "unprognostic (1.75e-1)" "unprognostic (2.55e-1)" "unprognostic (8.62e-2)" "unprognostic (4.27e-2)" "unprognostic (1.65e-1)" "unprognostic (5.49e-2)" "unprognostic (5.43e-2)" "unprognostic (1.86e-2)" "unprognostic (3.69e-2)" "unprognostic (6.41e-2)" "unprognostic (5.10e-2)" "unprognostic (6.22e-2)" "unprognostic (3.63e-2)" "unprognostic (8.39e-2)" "unprognostic (1.36e-1)" "unprognostic (1.99e-2)" "unprognostic (2.54e-1)" BIVM-ERCC5 ENSG00000270181 "BIVM-ERCC5 readthrough" 13 102799110-102875994 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Epicardial cells: 4.5;Mucous neck cells: 3.2;Myonuclei: 6.4;Paneth cells: 3.9;Parietal cells: 3.5;Retinal amacrine cells: 3.4;Retinal pigment epithelial cells: 4.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Kidney cancer: 1.0" "HPA045845, HPA050126, HPA050374" Uncertain Approved Nucleoplasm NA NA "Cluster 37: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 55: Myocytes - Oxidative muscle function" Nucleoplasm "HPA045845: , HPA050126: , HPA050374: " BLACAT1 "linc-UBC1, LINC00912, onco-lncRNA-30" ENSG00000281406 "BLACAT1 overlapping LEMD1 locus" 1 205434885-205457091 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 6.7;epididymis: 3.7" "Group enriched" "Detected in some" 5 "Retinal bipolar cells: 7.5;Retinal ganglion cells: 3.9" "Group enriched" "Detected in some" 5 "lower rhombic lip: 5.5;upper rhombic lip: 3.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Urothelial cells, Skin - Hair cortex cells, Skin - Outer root sheath cells, Testis - Sertoli cells" NA NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 49: Hindbrain - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "unprognostic (1.29e-1)" "unprognostic (1.08e-1)" "unprognostic (1.85e-1)" "unprognostic (8.85e-2)" "unprognostic (5.19e-3)" "unprognostic (9.25e-2)" "unprognostic (1.50e-1)" "unprognostic (8.33e-2)" "unprognostic (2.91e-1)" "unprognostic (6.26e-2)" "unprognostic (7.73e-3)" "unprognostic (9.45e-3)" "unprognostic (1.04e-1)" "unprognostic (1.93e-2)" "unprognostic (3.99e-1)" "unprognostic (2.66e-1)" "unprognostic (9.70e-2)" BLCAP BC10 ENSG00000166619 "BLCAP apoptosis inducing factor" P62952 20 37492472-37527931 "Predicted intracellular proteins" "Apoptosis, Cell cycle" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 452.1" "Cell type enhanced" "Detected in all" "Adipocytes: 308.6;Late spermatids: 311.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047390 Approved Nucleoli NA NA "Cluster 32: Basophils - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 14 Nucleoli "HPA047390: " "unprognostic (3.82e-2)" "unprognostic (3.78e-2)" "unprognostic (4.06e-1)" "unprognostic (2.68e-2)" "unprognostic (1.54e-3)" "unprognostic (6.50e-2)" "unprognostic (1.36e-1)" "unprognostic (3.48e-3)" "unprognostic (1.60e-3)" "unprognostic (2.08e-1)" "unprognostic (6.97e-3)" "unprognostic (1.31e-1)" "unprognostic (2.43e-2)" "unprognostic (3.59e-1)" "unprognostic (4.24e-1)" "unprognostic (8.13e-2)" "unprognostic (2.25e-1)" "unprognostic (1.48e-1)" "unprognostic (1.36e-1)" "unprognostic (4.21e-3)" "unprognostic (4.72e-2)" "unprognostic (4.40e-2)" "unprognostic (7.63e-2)" "unprognostic (1.62e-1)" "unprognostic (3.36e-2)" "unprognostic (2.53e-2)" "unprognostic (2.38e-1)" "unprognostic (5.92e-2)" "unprognostic (2.00e-1)" "unprognostic (5.60e-2)" "unprognostic (3.94e-2)" BLID BRCC2 ENSG00000259571 "BH3-like motif containing, cell death inducer" Q8IZY5 11 122115340-122116215 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 4 "Proximal tubule cells: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA054411 Approved Cytosol NA NA "Cluster 11: White matter - Signal transduction" "Cluster 72: Neuronal - Signal transduction" "Cluster 88: Proximal tubular cells - Transmembrane transport" 1 Cytosol "HPA054411: " "unprognostic (1.10e-1)" BLK MGC10442 ENSG00000136573 "BLK proto-oncogene, Src family tyrosine kinase" P51451 8 11486894-11564599 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 19 "intestine: 40.2;lymphoid tissue: 49.9" "Cell type enriched" "Detected in some" 15 "B-cells: 165.6" "Cell type enriched" "Detected in some" 26 "leukocyte: 32.4" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "memory B-cell: 167.9;naive B-cell: 118.0" "Lineage enriched" "Detected in many" 5 "B-cells: 167.9" "Cancer enriched" "Detected in some" 4 "lymphoma: 64.1" "Lung - B-cells (Lung), Minor Salivary Gland - Plasma cells, Spleen - B-cells (Spleen)" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB005093, HPA069571" Approved Uncertain Nucleoplasm NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 42 Nucleoplasm "CAB005093: , HPA069571: " "unprognostic (6.08e-3)" "unprognostic (3.42e-1)" "unprognostic (1.66e-3)" "unprognostic (8.21e-2)" "unprognostic (1.15e-1)" "unprognostic (2.65e-2)" "unprognostic (4.65e-2)" BLM "BS, RECQ2, RECQL3" ENSG00000197299 "BLM RecQ like helicase" P54132 15 90717346-90816166 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication" "DNA-binding, Helicase, Hydrolase, Isomerase" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.3;lymphoid tissue: 7.4;salivary gland: 7.4" "Cell type enhanced" "Detected in many" "Bergmann glia: 259.0;Cardiomyocytes: 65.9;Erythrocyte progenitors: 91.5;Megakaryocyte progenitors: 87.2;Monocyte progenitors: 130.4;Neutrophil progenitors: 80.9;Oligodendrocyte progenitor cells: 119.8;Salivary acinar cells: 290.9;Salivary myoepithelial cells: 83.7;Tuft cells: 80.7" "Group enriched" "Detected in many" 7 "Bergmann glia: 286.6;oligodendrocyte precursor cell: 138.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Heart muscle - Cardiomyocytes, Lung - Mitotic cells (Lung), Pancreas - Macrophages, Pituitary gland - Corticotropes, Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005689 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 25: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 102 Nucleoplasm Cytosol "HPA005689: " "unprognostic (5.38e-2)" "unprognostic (1.51e-1)" "unprognostic (1.16e-1)" "unprognostic (7.74e-2)" "unprognostic (9.21e-2)" "unprognostic (2.32e-1)" "unprognostic (9.77e-2)" "unprognostic (2.60e-2)" "unprognostic (1.60e-1)" "potential prognostic unfavorable (1.77e-4)" "potential prognostic unfavorable (1.19e-4)" "unprognostic (1.73e-3)" "unprognostic (1.58e-1)" "unprognostic (9.32e-2)" "unprognostic (1.56e-1)" "unprognostic (2.45e-2)" "unprognostic (1.18e-3)" "potential prognostic favorable (3.17e-5)" "unprognostic (6.77e-2)" "unprognostic (1.20e-2)" "unprognostic (9.94e-3)" "unprognostic (2.32e-1)" "unprognostic (8.94e-3)" BLMH BH ENSG00000108578 "Bleomycin hydrolase" Q13867 17 30248203-30292056 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 128.4" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039548, HPA064307" Enhanced Supported "Nucleoplasm,Nuclear bodies,Cytosol" No No 22000000 "Cluster 11: T-cells - Unknown function" "Cluster 9: Skin - Hair follicle development" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 1: Neuronal - Visual perception" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 29 "Nucleoplasm, Nuclear bodies, Cytosol" "HPA039548: , HPA064307: " "unprognostic (7.03e-2)" "unprognostic (1.09e-1)" "potential prognostic favorable (2.43e-4)" "unprognostic (1.54e-1)" "unprognostic (1.77e-3)" "unprognostic (3.58e-2)" "unprognostic (8.04e-2)" "unprognostic (1.88e-3)" "unprognostic (7.47e-2)" "unprognostic (3.98e-2)" "validated prognostic favorable (4.44e-6)" "validated prognostic favorable (2.28e-4)" "unprognostic (1.41e-1)" "validated prognostic unfavorable (7.17e-4)" "validated prognostic unfavorable (4.49e-4)" "unprognostic (3.73e-2)" "unprognostic (5.00e-1)" "unprognostic (3.00e-2)" "unprognostic (2.76e-3)" "unprognostic (1.48e-2)" "unprognostic (3.56e-1)" "unprognostic (4.19e-3)" "unprognostic (4.43e-2)" "unprognostic (1.42e-1)" "unprognostic (8.85e-2)" "unprognostic (3.22e-3)" "unprognostic (5.66e-3)" "potential prognostic unfavorable (2.72e-4)" "unprognostic (3.26e-1)" "unprognostic (1.12e-1)" "unprognostic (2.31e-1)" BLNK "BASH, bca, BLNK-s, Ly57, SLP-65, SLP65" ENSG00000095585 "B cell linker" Q8WV28 10 96189171-96271587 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "B-cell activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 52.9" "Cell type enhanced" "Detected in many" "B-cells: 211.3;Distal convoluted tubule cells: 301.5;Epididymal clear cells: 210.3;Esophageal apical cells: 670.8;Microglia: 703.1;Ocular epithelial cells: 249.0;pDCs: 330.4;Plasma cells: 208.7;Renal collecting duct intercalated cells: 180.9;Renal collecting duct principal cells: 215.1;Renal connecting tubule cells: 260.7" "Cell type enriched" "Detected in all" 14 "central nervous system macrophage: 868.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "memory B-cell: 111.3;naive B-cell: 94.9;plasmacytoid DC: 159.3" "Group enriched" "Detected in many" 83 "B-cells: 111.3;dendritic cells: 159.3" "Cancer enhanced" "Detected in many" "Leukemia: 18.6;lymphoma: 53.4" "Adrenal gland - Macrophages, Spleen - B-cells (Spleen), Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB009333, CAB016291, HPA038309, HPA038310" Enhanced Supported "Vesicles,Plasma membrane" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 20 "Plasma membrane" Vesicles "CAB009333: , CAB016291: , HPA038309: , HPA038310: " "unprognostic (1.04e-1)" "unprognostic (4.21e-2)" "unprognostic (2.09e-1)" "unprognostic (9.07e-2)" "unprognostic (7.83e-2)" "unprognostic (1.32e-1)" "unprognostic (3.05e-1)" "unprognostic (7.24e-2)" "unprognostic (4.68e-3)" "unprognostic (3.70e-2)" "potential prognostic favorable (4.34e-5)" "unprognostic (2.09e-1)" "unprognostic (4.28e-3)" "unprognostic (4.32e-2)" "potential prognostic favorable (4.44e-4)" "unprognostic (1.47e-2)" "unprognostic (1.05e-3)" "unprognostic (7.35e-2)" "unprognostic (2.54e-2)" "unprognostic (2.44e-1)" "unprognostic (1.07e-1)" "unprognostic (1.99e-1)" "unprognostic (7.07e-3)" "unprognostic (1.32e-1)" "unprognostic (3.89e-2)" "unprognostic (3.46e-1)" "unprognostic (2.77e-1)" "unprognostic (1.52e-1)" "unprognostic (1.11e-1)" "unprognostic (7.03e-3)" "unprognostic (2.74e-2)" BLOC1S1 "BLOS1, BORCS1, GCN5L1" ENSG00000135441 "Biogenesis of lysosomal organelles complex 1 subunit 1" P78537 12 55716038-55720087 "Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 711.0;Enterocytes: 898.2;Esophageal apical cells: 639.0;Hofbauer cells: 387.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021381 Approved NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 26 "HPA021381: " "unprognostic (4.83e-2)" "unprognostic (3.72e-1)" "unprognostic (3.18e-2)" "unprognostic (1.88e-3)" "unprognostic (1.10e-1)" "unprognostic (2.68e-1)" "unprognostic (1.29e-1)" "unprognostic (5.78e-2)" "unprognostic (2.47e-1)" "unprognostic (2.49e-3)" "unprognostic (1.51e-1)" "unprognostic (5.27e-1)" "unprognostic (1.40e-2)" "unprognostic (1.06e-1)" "unprognostic (2.85e-1)" "unprognostic (1.36e-1)" "unprognostic (1.67e-1)" "unprognostic (4.42e-2)" "unprognostic (1.11e-1)" "unprognostic (2.05e-3)" "unprognostic (1.96e-1)" "unprognostic (1.15e-2)" "unprognostic (1.21e-1)" "unprognostic (1.01e-1)" "unprognostic (1.10e-2)" "unprognostic (2.04e-1)" "unprognostic (2.64e-1)" "unprognostic (2.81e-2)" "unprognostic (1.47e-1)" "unprognostic (3.43e-2)" "unprognostic (9.91e-2)" BLOC1S2 "BLOS2, BORCS2, FLJ30135, MGC10120" ENSG00000196072 "Biogenesis of lysosomal organelles complex 1 subunit 2" Q6QNY1 10 100273280-100286680 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 215.9;Esophageal basal cells: 161.5;Esophageal suprabasal cells: 287.6;Kupffer cells: 192.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048088, HPA055010" Approved NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 85: Squamous epithelial cells - Keratinization" 59 "HPA048088: , HPA055010: " "unprognostic (1.92e-1)" "unprognostic (8.78e-3)" "unprognostic (2.04e-1)" "unprognostic (2.70e-1)" "unprognostic (9.11e-2)" "unprognostic (1.50e-2)" "unprognostic (1.93e-1)" "unprognostic (1.07e-1)" "unprognostic (5.13e-2)" "unprognostic (9.30e-2)" "potential prognostic favorable (2.31e-4)" "unprognostic (2.56e-1)" "unprognostic (3.71e-2)" "unprognostic (1.30e-2)" "unprognostic (2.38e-1)" "unprognostic (6.19e-2)" "unprognostic (2.19e-1)" "unprognostic (9.56e-2)" "unprognostic (2.08e-1)" "unprognostic (2.08e-2)" "potential prognostic unfavorable (2.10e-9)" "unprognostic (5.90e-2)" "unprognostic (5.63e-3)" "unprognostic (4.26e-2)" "unprognostic (6.06e-3)" "unprognostic (7.92e-2)" "unprognostic (8.18e-2)" "unprognostic (1.39e-1)" "unprognostic (1.80e-1)" "unprognostic (2.30e-1)" "unprognostic (3.73e-1)" BLOC1S3 "BLOS3, HPS8" ENSG00000189114 "Biogenesis of lysosomal organelles complex 1 subunit 3" Q6QNY0 19 45178784-45216933 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Albinism, Hermansky-Pudlak syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in some" 10 "Late spermatids: 96.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Sertoli cells" "Low region specificity" "Detected in all" "HPA050111, HPA070609" Approved Approved "Golgi apparatus" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 2: Non-specific - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 4: Non-specific - Transcription" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 14 "Golgi apparatus" "HPA050111: , HPA070609: " "unprognostic (1.46e-2)" "unprognostic (1.96e-2)" "unprognostic (2.09e-2)" "unprognostic (1.11e-1)" "unprognostic (3.76e-2)" "unprognostic (8.47e-3)" "unprognostic (1.77e-1)" "unprognostic (1.71e-2)" "unprognostic (9.76e-3)" "unprognostic (8.85e-3)" "unprognostic (3.11e-1)" "unprognostic (5.44e-2)" "unprognostic (1.65e-1)" "unprognostic (2.54e-3)" "unprognostic (9.16e-3)" "unprognostic (1.55e-2)" "unprognostic (1.24e-1)" "unprognostic (4.91e-3)" "unprognostic (8.89e-2)" "unprognostic (2.27e-2)" "unprognostic (7.40e-2)" "unprognostic (1.74e-2)" "unprognostic (7.13e-2)" "unprognostic (5.88e-2)" "unprognostic (2.96e-1)" "unprognostic (3.08e-1)" "unprognostic (1.26e-1)" "unprognostic (2.81e-1)" "unprognostic (1.48e-1)" "unprognostic (3.80e-2)" "unprognostic (1.64e-1)" BLOC1S4 "BCAS4L, CNO, FLJ11230" ENSG00000186222 "Biogenesis of lysosomal organelles complex 1 subunit 4" Q9NUP1 4 6716174-6717664 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 112.7;Extravillous trophoblasts: 114.0;Migrating cytotrophoblasts: 96.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043840 Approved Approved Vesicles,Cytosol NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 8 Vesicles Cytosol "HPA043840: " "unprognostic (1.09e-1)" "unprognostic (7.16e-2)" "unprognostic (3.23e-3)" "unprognostic (8.84e-2)" "unprognostic (2.44e-2)" "unprognostic (3.34e-3)" "unprognostic (5.02e-1)" "unprognostic (1.05e-1)" "unprognostic (2.51e-1)" "unprognostic (2.47e-3)" "unprognostic (8.78e-3)" "unprognostic (3.19e-1)" "potential prognostic unfavorable (1.70e-7)" "potential prognostic unfavorable (6.36e-4)" "unprognostic (1.43e-3)" "unprognostic (1.62e-2)" "unprognostic (2.21e-1)" "unprognostic (6.19e-2)" "unprognostic (1.48e-1)" "unprognostic (2.36e-2)" "unprognostic (1.22e-1)" "unprognostic (7.10e-2)" "unprognostic (9.92e-2)" "unprognostic (2.87e-1)" "unprognostic (4.38e-2)" "unprognostic (2.17e-1)" "unprognostic (1.01e-1)" "unprognostic (2.00e-1)" "unprognostic (5.11e-2)" BLOC1S5 "dJ303A1.3, MU, MUTED" ENSG00000188428 "Biogenesis of lysosomal organelles complex 1 subunit 5" Q8TDH9 6 8013567-8064396 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Albinism, Hermansky-Pudlak syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 3.1;Bergmann glia: 3.0;Brain excitatory neurons: 2.7;Brain inhibitory neurons: 2.7;Ependymal cells: 4.8;Late spermatids: 4.7;Megakaryocyte-Erythroid progenitors: 2.4;Microglia: 5.1;Oligodendrocyte progenitor cells: 3.6;Oligodendrocytes: 3.8;Other brain neurons: 3.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025613, HPA077525" Uncertain Supported Vesicles NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 72: Kidney - Transmembrane transport" "Cluster 27: Non-specific - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 22: Non-specific - Basic cellular functions" 31 Vesicles "CAB025613: , HPA077525: " "unprognostic (3.74e-2)" "unprognostic (6.30e-2)" "unprognostic (9.93e-2)" "unprognostic (2.21e-1)" "unprognostic (9.08e-3)" "unprognostic (1.57e-1)" "unprognostic (2.04e-1)" "unprognostic (1.54e-1)" "unprognostic (5.03e-2)" "potential prognostic favorable (7.01e-7)" "unprognostic (1.98e-3)" "unprognostic (2.52e-1)" "unprognostic (1.56e-3)" "unprognostic (5.15e-2)" "unprognostic (6.99e-2)" "unprognostic (1.89e-1)" "unprognostic (8.35e-3)" "unprognostic (1.35e-2)" "unprognostic (2.14e-2)" "unprognostic (3.23e-2)" "unprognostic (2.55e-1)" "unprognostic (2.64e-1)" "unprognostic (3.04e-3)" "unprognostic (2.33e-1)" "unprognostic (3.36e-2)" "unprognostic (7.71e-2)" "unprognostic (1.84e-1)" "unprognostic (9.83e-2)" "unprognostic (9.72e-2)" BLOC1S6 "HPS9, PA, PLDN" ENSG00000104164 "Biogenesis of lysosomal organelles complex 1 subunit 6" Q9UL45 15 45587214-45615945 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Albinism, Disease variant, Hermansky-Pudlak syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 41.1;Brain inhibitory neurons: 39.3;Late spermatids: 33.7;Microglia: 46.8;Oligodendrocyte progenitor cells: 38.3;Oligodendrocytes: 44.3;Other brain neurons: 49.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA039928 Approved NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 1: Neurons - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 22: Non-specific - Basic cellular functions" 61 "HPA039928: " "unprognostic (1.52e-2)" "unprognostic (4.26e-2)" "unprognostic (3.20e-2)" "unprognostic (2.08e-1)" "unprognostic (3.01e-1)" "unprognostic (1.86e-1)" "unprognostic (3.08e-2)" "unprognostic (3.48e-1)" "unprognostic (6.29e-2)" "potential prognostic favorable (8.58e-6)" "unprognostic (8.11e-3)" "unprognostic (2.01e-1)" "potential prognostic unfavorable (9.45e-4)" "unprognostic (3.67e-1)" "unprognostic (3.22e-2)" "unprognostic (1.78e-1)" "unprognostic (2.54e-2)" "unprognostic (9.07e-3)" "unprognostic (2.29e-1)" "unprognostic (6.28e-2)" "unprognostic (6.80e-3)" "unprognostic (3.62e-2)" "unprognostic (5.06e-2)" "unprognostic (4.53e-2)" "unprognostic (3.47e-2)" "unprognostic (9.05e-2)" "unprognostic (4.33e-2)" "unprognostic (1.40e-2)" "unprognostic (3.03e-1)" BLTP1 "FLJ21404, FSA, KIAA1109, KIAA1371, Tweek" ENSG00000138688 "Bridge-like lipid transfer protein family member 1" Q2LD37 4 122152331-122364167 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 837.6" "Cell type enhanced" "Detected in all" "pericyte: 1439.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 1.9" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038076 Approved Approved Nucleoplasm,Centrosome NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 2 "Nucleoplasm, Centrosome" "HPA038076: " "unprognostic (5.10e-3)" "unprognostic (3.63e-2)" "unprognostic (6.91e-2)" "unprognostic (7.03e-3)" "unprognostic (2.03e-1)" "unprognostic (2.80e-1)" "unprognostic (1.48e-1)" "unprognostic (2.39e-2)" "unprognostic (1.28e-2)" "unprognostic (4.40e-3)" "validated prognostic favorable (5.88e-7)" "validated prognostic favorable (2.32e-5)" "unprognostic (7.04e-3)" "unprognostic (2.34e-2)" "unprognostic (1.18e-2)" "unprognostic (1.37e-2)" "unprognostic (2.21e-1)" "unprognostic (5.90e-2)" "unprognostic (1.30e-1)" "unprognostic (3.17e-3)" "unprognostic (9.96e-2)" "unprognostic (1.53e-1)" "unprognostic (2.63e-2)" "unprognostic (5.49e-2)" "unprognostic (1.18e-3)" "potential prognostic favorable (8.32e-4)" "unprognostic (7.64e-2)" "unprognostic (1.71e-1)" "unprognostic (1.72e-1)" "unprognostic (2.71e-2)" "unprognostic (2.59e-1)" BLTP2 "BCOX, BCOX1, CT101, DKFZp686M0843, FMP27, Hob, KIAA0100, MGC111488" ENSG00000007202 "Bridge-like lipid transfer protein family member 2" Q14667 17 28614446-28645454 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042781 Uncertain Approved "Nuclear speckles,Cytosol" No No "Cluster 13: Non-specific - Mitochondria" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 4 "Nuclear speckles, Cytosol" "HPA042781: " "unprognostic (1.67e-1)" "unprognostic (1.61e-1)" "unprognostic (1.92e-1)" "unprognostic (3.01e-2)" "unprognostic (5.45e-2)" "unprognostic (1.71e-1)" "unprognostic (1.52e-1)" "unprognostic (1.81e-2)" "unprognostic (4.02e-2)" "unprognostic (1.57e-2)" "potential prognostic favorable (2.44e-4)" "unprognostic (1.30e-1)" "unprognostic (1.43e-3)" "potential prognostic unfavorable (1.65e-4)" "unprognostic (3.50e-3)" "unprognostic (1.31e-1)" "unprognostic (3.39e-1)" "unprognostic (2.11e-2)" "unprognostic (7.89e-2)" "unprognostic (1.10e-3)" "unprognostic (2.17e-1)" "unprognostic (1.67e-2)" "unprognostic (8.62e-2)" "unprognostic (2.33e-1)" "unprognostic (1.81e-3)" "unprognostic (1.34e-2)" "unprognostic (1.77e-1)" "unprognostic (1.83e-1)" "unprognostic (1.94e-1)" "unprognostic (7.91e-2)" "unprognostic (2.61e-1)" BLTP3A "C6orf107, dJ349A12.1, FLJ20302, UHRF1BP1" ENSG00000065060 "Bridge-like lipid transfer protein family member 3A" Q6BDS2 6 34792083-34877514 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 120.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.2" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032099, HPA032100" Uncertain Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 63: Non-specific - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 13: Non-specific - Mixed function" "Cluster 7: Non-specific - Transcription" 8 "Nucleoplasm, Nuclear membrane" Cytosol "HPA032099: , HPA032100: " "unprognostic (1.48e-1)" "unprognostic (2.66e-2)" "unprognostic (1.39e-1)" "unprognostic (1.08e-1)" "unprognostic (1.66e-2)" "unprognostic (6.57e-3)" "unprognostic (5.64e-2)" "unprognostic (2.56e-2)" "unprognostic (6.26e-2)" "unprognostic (2.35e-3)" "potential prognostic favorable (2.00e-4)" "unprognostic (1.32e-1)" "unprognostic (1.94e-1)" "unprognostic (1.07e-3)" "unprognostic (1.73e-2)" "unprognostic (2.11e-1)" "unprognostic (5.79e-2)" "unprognostic (4.75e-2)" "unprognostic (1.48e-1)" "unprognostic (1.28e-1)" "unprognostic (1.13e-1)" "unprognostic (3.03e-1)" "unprognostic (3.39e-2)" "unprognostic (7.23e-2)" "potential prognostic favorable (4.81e-4)" "unprognostic (2.53e-2)" "unprognostic (2.79e-3)" "unprognostic (4.73e-2)" "unprognostic (1.22e-1)" "unprognostic (1.62e-1)" "unprognostic (1.32e-1)" BLTP3B "KIAA0701, SHIP164, UHRF1BP1L" ENSG00000111647 "Bridge-like lipid transfer protein family member 3B" A0JNW5 12 100028455-100142874 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 481.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039671, HPA075150" Uncertain Uncertain Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 41: Basophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 32 Nucleoplasm "Vesicles, Cytosol" "HPA039671: , HPA075150: " "unprognostic (1.43e-1)" "unprognostic (3.90e-2)" "unprognostic (3.88e-1)" "unprognostic (7.69e-2)" "unprognostic (1.12e-1)" "unprognostic (1.08e-1)" "unprognostic (1.09e-1)" "unprognostic (1.70e-1)" "unprognostic (2.29e-1)" "potential prognostic unfavorable (6.12e-4)" "potential prognostic favorable (2.69e-6)" "unprognostic (2.51e-1)" "unprognostic (2.65e-1)" "unprognostic (1.25e-2)" "unprognostic (8.28e-2)" "unprognostic (6.69e-3)" "unprognostic (1.82e-2)" "unprognostic (7.34e-2)" "unprognostic (3.39e-1)" "unprognostic (3.16e-2)" "unprognostic (3.40e-3)" "unprognostic (7.64e-3)" "unprognostic (1.73e-2)" "unprognostic (1.19e-1)" "unprognostic (2.33e-1)" "unprognostic (3.19e-3)" "unprognostic (3.01e-1)" "unprognostic (8.63e-2)" "unprognostic (3.02e-1)" "unprognostic (7.64e-2)" "unprognostic (2.23e-1)" BLVRA BLVR ENSG00000106605 "Biliverdin reductase A" P53004 7 43758680-43807342 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 620.7;Esophageal apical cells: 375.6;Esophageal suprabasal cells: 155.8;Hofbauer cells: 481.3;Kupffer cells: 212.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Prostate - Smooth muscle cells, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019709, HPA042865, HPA054322" Approved Supported Cytosol NA NA 2600000 "Cluster 25: Non-specific - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 67: Non-specific - Unknown function" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 17 Cytosol "HPA019709: , HPA042865: , HPA054322: " "unprognostic (2.17e-2)" "unprognostic (9.78e-2)" "unprognostic (1.18e-1)" "unprognostic (7.06e-3)" "unprognostic (3.00e-1)" "unprognostic (3.35e-2)" "potential prognostic unfavorable (7.46e-5)" "unprognostic (1.11e-1)" "unprognostic (5.81e-2)" "unprognostic (6.54e-2)" "potential prognostic favorable (6.95e-5)" "unprognostic (1.97e-1)" "unprognostic (1.84e-3)" "unprognostic (1.24e-2)" "unprognostic (1.19e-2)" "unprognostic (3.43e-1)" "unprognostic (2.54e-1)" "unprognostic (4.42e-2)" "unprognostic (2.08e-1)" "unprognostic (4.95e-2)" "unprognostic (2.87e-1)" "unprognostic (1.39e-1)" "unprognostic (2.66e-2)" "unprognostic (1.95e-1)" "unprognostic (3.38e-2)" "unprognostic (3.19e-1)" "unprognostic (8.92e-2)" "unprognostic (1.43e-3)" "unprognostic (1.92e-1)" "unprognostic (5.96e-2)" "unprognostic (1.05e-1)" BLVRB "FLR, SDR43U1" ENSG00000090013 "Biliverdin reductase B" P30043 19 40447765-40465764 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Oxidoreductase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 588.8" "Cell type enhanced" "Detected in many" "Enterocytes: 925.2;Erythrocyte progenitors: 1710.2;Erythrocytes: 921.8;Esophageal apical cells: 3709.2;Hepatocytes: 861.7;Hofbauer cells: 2026.0;Kupffer cells: 873.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 466.2" "Group enriched" "Detected in all" 7 "dendritic cells: 343.8;monocytes: 466.2" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041698, HPA041937" Enhanced Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" No No 210000000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 15: Bone marrow - Innate immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 84: Apical squamous epithelium - Cornification" 9 Cytosol "Nucleoplasm, Vesicles, Plasma membrane" "HPA041698: , HPA041937: " "unprognostic (2.10e-2)" "unprognostic (6.71e-2)" "unprognostic (1.95e-1)" "potential prognostic favorable (3.06e-4)" "unprognostic (1.66e-1)" "unprognostic (2.95e-3)" "unprognostic (3.66e-3)" "unprognostic (1.81e-1)" "unprognostic (1.33e-1)" "unprognostic (2.59e-2)" "unprognostic (1.06e-3)" "unprognostic (5.50e-2)" "unprognostic (2.61e-2)" "unprognostic (2.36e-1)" "unprognostic (2.09e-2)" "potential prognostic unfavorable (2.26e-4)" "unprognostic (1.27e-1)" "unprognostic (3.31e-2)" "unprognostic (1.05e-1)" "unprognostic (5.15e-2)" "unprognostic (2.38e-1)" "potential prognostic unfavorable (7.61e-5)" "unprognostic (8.66e-2)" "unprognostic (2.79e-1)" "unprognostic (5.16e-1)" "unprognostic (2.11e-1)" "unprognostic (2.99e-1)" "unprognostic (1.67e-1)" "unprognostic (8.85e-3)" "unprognostic (9.67e-3)" "unprognostic (5.01e-2)" BLZF1 JEM-1 ENSG00000117475 "Basic leucine zipper nuclear factor 1" Q9H2G9 1 169367970-169396540 "Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epididymal basal cells: 180.1;Esophageal apical cells: 314.0;Late primary spermatocytes: 180.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 85.9" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025703, HPA027331, HPA067113" Supported Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 42: Retina - Visual perception" "Cluster 55: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 102 "Golgi apparatus" Nucleoplasm "HPA025703: , HPA027331: , HPA067113: " "unprognostic (1.93e-1)" "unprognostic (5.35e-3)" "unprognostic (2.87e-1)" "unprognostic (2.17e-2)" "unprognostic (1.35e-1)" "unprognostic (1.44e-1)" "unprognostic (2.06e-1)" "unprognostic (3.71e-1)" "unprognostic (1.90e-1)" "unprognostic (6.09e-3)" "potential prognostic favorable (3.56e-6)" "unprognostic (9.87e-3)" "unprognostic (3.02e-3)" "unprognostic (9.22e-3)" "unprognostic (2.29e-1)" "potential prognostic unfavorable (5.97e-4)" "unprognostic (2.63e-3)" "unprognostic (1.65e-1)" "unprognostic (2.05e-1)" "unprognostic (1.75e-1)" "potential prognostic unfavorable (5.03e-4)" "unprognostic (7.24e-3)" "unprognostic (4.65e-3)" "unprognostic (2.14e-3)" "unprognostic (1.12e-1)" "unprognostic (4.49e-2)" "unprognostic (1.35e-1)" "unprognostic (1.96e-1)" "unprognostic (4.95e-2)" "unprognostic (1.98e-2)" "unprognostic (1.23e-1)" BMAL1 "ARNTL, ARNTL1, bHLHe5, JAP3, MOP3, PASD3" ENSG00000133794 "Basic helix-loop-helix ARNT like 1" O00327 11 13276652-13387266 "Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 174.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Thyroid Carcinoma (TCGA): 19.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB045962, HPA050938" Supported Supported Nucleoplasm,Vesicles NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 20 Nucleoplasm Vesicles "CAB045962: , HPA050938: " "unprognostic (2.00e-1)" "unprognostic (1.19e-1)" "unprognostic (1.24e-1)" "unprognostic (1.79e-1)" "unprognostic (1.57e-1)" "unprognostic (6.58e-3)" "unprognostic (2.74e-1)" "unprognostic (2.64e-3)" "unprognostic (2.78e-1)" "unprognostic (3.34e-3)" "unprognostic (4.16e-3)" "unprognostic (2.35e-3)" "unprognostic (1.60e-1)" "unprognostic (3.32e-1)" "unprognostic (2.97e-1)" "unprognostic (1.17e-1)" "unprognostic (7.68e-3)" "unprognostic (1.99e-1)" "unprognostic (1.15e-1)" "unprognostic (1.40e-2)" "unprognostic (3.12e-1)" "unprognostic (3.15e-1)" "potential prognostic unfavorable (1.89e-5)" "unprognostic (1.49e-1)" "unprognostic (2.23e-1)" "unprognostic (9.75e-2)" "unprognostic (3.56e-1)" "unprognostic (3.80e-2)" "unprognostic (7.42e-2)" "unprognostic (3.03e-2)" "unprognostic (2.81e-2)" BMAL2 "ARNTL2, bHLHe6, CLIF, MOP9, PASD9" ENSG00000029153 "Basic helix-loop-helix ARNT like 2" Q8WYA1 12 27332836-27425289 "Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 26.1;lymphoid tissue: 20.5" "Cell type enhanced" "Detected in many" "Endometrial secretory cells: 195.1;Esophageal apical cells: 717.0;Respiratory basal cells: 233.1;Respiratory deuterosomal cells: 193.8;Respiratory secretory cells: 120.5;Salivary basal cells: 125.7;Suprabasal keratinocytes: 142.8;Urothelial cells: 396.1" "Cell type enhanced" "Detected in all" "deep-layer near-projecting: 205.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Liver - Neutrophils, Skeletal muscle - Endothelial cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA059074 Uncertain Supported Nucleoplasm,Nucleoli No No "Cluster 81: Squamous epithelium - Keratinization" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 72: Neuronal - Signal transduction" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 4 "Nucleoplasm, Nucleoli" "HPA059074: " "unprognostic (2.01e-1)" "unprognostic (1.86e-2)" "unprognostic (2.70e-1)" "unprognostic (2.31e-2)" "unprognostic (1.08e-1)" "unprognostic (3.71e-3)" "unprognostic (1.76e-1)" "unprognostic (9.19e-3)" "unprognostic (9.29e-2)" "unprognostic (6.98e-3)" "unprognostic (1.40e-3)" "unprognostic (1.04e-1)" "unprognostic (1.19e-1)" "unprognostic (1.20e-2)" "unprognostic (2.07e-2)" "validated prognostic unfavorable (2.55e-6)" "validated prognostic unfavorable (4.19e-4)" "unprognostic (6.22e-2)" "unprognostic (5.23e-2)" "unprognostic (1.42e-1)" "unprognostic (1.10e-2)" "validated prognostic unfavorable (7.29e-8)" "validated prognostic unfavorable (5.68e-6)" "unprognostic (1.82e-3)" "unprognostic (9.29e-2)" "unprognostic (1.79e-2)" "unprognostic (3.81e-2)" "unprognostic (2.68e-1)" "unprognostic (2.69e-1)" "unprognostic (1.17e-2)" BMERB1 "C16orf45, FLJ32618" ENSG00000166780 "BMERB domain containing 1" Q96MC5 16 15434475-15625028 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 190.4" "Cell type enhanced" "Detected in many" "Bergmann glia: 69.0;Brain excitatory neurons: 129.8;Brain inhibitory neurons: 116.3;Choroid plexus epithelial cells: 73.3;Distal convoluted tubule cells: 125.1;Early spermatids: 77.0;Late primary spermatocytes: 62.4;Late spermatids: 312.9;Oligodendrocyte progenitor cells: 156.3;Oligodendrocytes: 92.6;Other brain neurons: 126.5;Papillary tip epithelial cells: 72.6;Podocytes: 95.5;Renal connecting tubule cells: 66.9" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 94.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 8.8" "Group enriched" "Detected in many" 8 "B-cells: 2.2;T-cells: 8.8" "Cancer enhanced" "Detected in many" "Rhabdoid: 69.1" "Adipose visceral - Adipose progenitor cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041114, HPA063757" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 27: T-cells - Unknown function" "Cluster 73: Brain - Neuronal signaling" "Cluster 24: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 102: Non-specific - Mixed function" 5 Cytosol Nucleoplasm "HPA041114: , HPA063757: " "potential prognostic favorable (2.97e-4)" "unprognostic (7.56e-2)" "unprognostic (2.15e-1)" "unprognostic (1.97e-2)" "unprognostic (2.20e-1)" "unprognostic (3.60e-2)" "unprognostic (1.07e-2)" "unprognostic (8.86e-2)" "unprognostic (1.37e-1)" "validated prognostic favorable (4.98e-4)" "validated prognostic favorable (4.20e-6)" "potential prognostic favorable (5.84e-4)" "potential prognostic favorable (1.89e-5)" "unprognostic (2.13e-1)" "unprognostic (1.96e-1)" "unprognostic (9.05e-3)" "unprognostic (1.45e-1)" "unprognostic (3.77e-2)" "unprognostic (4.32e-3)" "unprognostic (5.71e-2)" "unprognostic (3.13e-1)" "unprognostic (6.94e-2)" "unprognostic (1.23e-2)" "unprognostic (6.30e-2)" "unprognostic (2.33e-2)" "unprognostic (4.66e-3)" "unprognostic (3.85e-2)" "unprognostic (2.66e-1)" "unprognostic (1.52e-1)" BMF FLJ00065 ENSG00000104081 "Bcl2 modifying factor" Q96LC9 15 40087890-40108892 "Essential proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 70.7" "Cell type enhanced" "Detected in many" "Kupffer cells: 46.1;Plasma cells: 34.0;Thymocytes: 20.3;Tuft cells: 34.6" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 13.1;fibroblast: 10.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010120, HPA010603" Approved Approved Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 80: Thymus - Adaptive immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 32 Cytosol "HPA010120: , HPA010603: " "unprognostic (5.42e-2)" "unprognostic (2.61e-2)" "unprognostic (2.40e-3)" "unprognostic (7.94e-2)" "unprognostic (2.62e-1)" "unprognostic (1.59e-2)" "unprognostic (8.41e-2)" "unprognostic (3.79e-2)" "unprognostic (5.02e-3)" "unprognostic (2.91e-1)" "unprognostic (6.31e-3)" "unprognostic (6.41e-2)" "unprognostic (1.23e-1)" "unprognostic (2.23e-3)" "unprognostic (2.03e-2)" "unprognostic (1.64e-2)" "unprognostic (1.38e-2)" "unprognostic (9.91e-2)" "unprognostic (1.99e-1)" "unprognostic (1.01e-1)" "unprognostic (3.64e-1)" "unprognostic (8.42e-2)" "potential prognostic unfavorable (5.33e-4)" "unprognostic (3.42e-1)" "unprognostic (3.31e-2)" "unprognostic (2.36e-2)" "unprognostic (9.88e-2)" "unprognostic (1.65e-2)" "unprognostic (2.50e-1)" "unprognostic (1.72e-1)" "unprognostic (1.99e-1)" BMI1 "PCGF4, RNF51" ENSG00000168283 "BMI1 proto-oncogene, polycomb ring finger" P35226 10 22321099-22331484 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 182.7;Late spermatids: 264.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011120, HPA030471, HPA030472" Supported Approved "Nucleoplasm,Nucleoli,Nuclear bodies,Cytosol" NA NA "Cluster 32: Basophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 67: Plasma cells - Plasma cell differentiation" 125 "Nucleoplasm, Nuclear bodies" "Nucleoli, Cytosol" "CAB011120: , HPA030471: , HPA030472: " "unprognostic (2.13e-2)" "unprognostic (3.25e-1)" "unprognostic (1.80e-1)" "unprognostic (4.35e-2)" "unprognostic (1.93e-1)" "potential prognostic unfavorable (4.61e-5)" "unprognostic (5.39e-2)" "unprognostic (1.37e-3)" "unprognostic (1.28e-1)" "unprognostic (2.86e-1)" "potential prognostic favorable (8.77e-8)" "unprognostic (1.93e-2)" "unprognostic (1.81e-1)" "potential prognostic unfavorable (2.04e-4)" "unprognostic (9.31e-2)" "unprognostic (4.10e-2)" "unprognostic (1.10e-1)" "unprognostic (1.03e-1)" "unprognostic (2.25e-1)" "unprognostic (2.92e-2)" "unprognostic (1.45e-2)" "unprognostic (3.55e-1)" "unprognostic (3.11e-2)" "unprognostic (2.00e-1)" "unprognostic (1.08e-3)" "unprognostic (2.16e-2)" "unprognostic (9.35e-2)" "unprognostic (1.35e-1)" "unprognostic (1.73e-2)" "unprognostic (2.56e-1)" "unprognostic (3.40e-1)" BMP1 "BMP-1, PCOLC" ENSG00000168487 "Bone morphogenetic protein 1" P13497 8 22165140-22212326 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor, Hydrolase, Metalloprotease, Protease" "Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Alveolar cells type 2: 331.9" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 37.7;fibroblast: 38.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014572 Enhanced "Secreted to extracellular matrix" Cytokine NA NA 8800000 "Cluster 33: Non-specific - ATP binding" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 54: Immune cells - T cell receptor" "Cluster 15: Kidney cancer - Membrane components" "Cluster 81: Alveolar cells - Lung function" 4 "HPA014572: " "unprognostic (2.47e-1)" "unprognostic (7.60e-2)" "unprognostic (2.24e-1)" "unprognostic (1.27e-2)" "unprognostic (1.03e-1)" "unprognostic (2.16e-1)" "unprognostic (2.50e-2)" "unprognostic (8.42e-2)" "unprognostic (3.31e-2)" "unprognostic (2.08e-1)" "unprognostic (5.37e-2)" "unprognostic (4.42e-2)" "unprognostic (3.20e-2)" "unprognostic (1.82e-1)" "unprognostic (5.31e-3)" "validated prognostic unfavorable (2.36e-4)" "validated prognostic unfavorable (1.14e-4)" "unprognostic (2.46e-2)" "unprognostic (8.14e-2)" "unprognostic (9.69e-3)" "unprognostic (3.54e-3)" "unprognostic (5.50e-3)" "unprognostic (3.99e-3)" "unprognostic (1.24e-1)" "unprognostic (1.41e-1)" "unprognostic (2.12e-2)" "unprognostic (4.11e-2)" "unprognostic (4.86e-2)" "unprognostic (4.84e-2)" "unprognostic (2.13e-1)" "unprognostic (2.20e-1)" BMP10 ENSG00000163217 "Bone morphogenetic protein 10" O95393 2 68860909-68871397 "Predicted secreted proteins" "Cell adhesion" "Cytokine, Developmental protein, Growth factor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 118 "heart muscle: 727.2" "Cell type enriched" "Detected in some" 6 "Hepatic stellate cells: 12.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 27 "Gastric cancer: 9.4;Rhabdoid: 2.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to blood" Cytokine NA NA 8140 380000 "Cluster 35: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 51 BMP15 GDF9B ENSG00000130385 "Bone morphogenetic protein 15" O95972 X 50910735-50916641 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Cytokine, Growth factor" "Disease variant, Premature ovarian failure" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" Cytokine NA NA "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 1 BMP2 BMP2A ENSG00000125845 "Bone morphogenetic protein 2" P12643 20 6767686-6780246 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 193.1;Alveolar cells type 2: 170.1;Basal keratinocytes: 141.7;Colonocytes: 91.0;Epicardial cells: 81.9;Epididymal basal cells: 116.3;Lymphatic endothelial cells: 67.7;Pancreatic duct cells: 92.0;Pericytes: 62.3;Suprabasal keratinocytes: 73.2;Urothelial cells: 171.0" "Cell type enhanced" "Detected in many" "fibroblast: 41.7;oligodendrocyte precursor cell: 19.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 30.7" "Pancreas - Ductal cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA049966, HPA058610, CAB078457" Approved "Nucleoplasm,Vesicles,Plasma membrane,Primary cilium,Primary cilium tip,Primary cilium transition zone,Basal body,Cytosol" "Secreted to blood" Cytokine NA NA 24400 10000 "Cluster 13: Lung - Secretion" "Cluster 49: Hindbrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 69: Urothelial cells - Basic cellular functions" 10 Vesicles "Nucleoplasm, Plasma membrane, Primary cilium, Primary cilium tip, Primary cilium transition zone, Basal body, Cytosol" "CAB078457: , HPA049966: , HPA058610: " "unprognostic (4.43e-2)" "unprognostic (1.33e-1)" "unprognostic (1.35e-1)" "unprognostic (1.22e-1)" "unprognostic (1.47e-1)" "unprognostic (3.70e-2)" "unprognostic (4.88e-2)" "potential prognostic favorable (1.73e-4)" "unprognostic (1.25e-1)" "unprognostic (4.45e-3)" "potential prognostic favorable (1.77e-6)" "unprognostic (1.42e-1)" "unprognostic (1.90e-1)" "unprognostic (2.27e-3)" "unprognostic (8.00e-2)" "unprognostic (3.97e-2)" "unprognostic (5.29e-3)" "unprognostic (1.40e-3)" "unprognostic (1.29e-1)" "unprognostic (5.40e-3)" "unprognostic (3.94e-1)" "potential prognostic unfavorable (9.36e-4)" "unprognostic (1.44e-2)" "unprognostic (7.84e-2)" "unprognostic (1.81e-1)" "unprognostic (5.56e-1)" "unprognostic (3.91e-3)" "unprognostic (7.07e-2)" BMP2K "BIKe, DKFZp434K0614" ENSG00000138756 "BMP2 inducible kinase" Q9NSY1 4 78776342-78916365 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 433.2;Erythrocyte progenitors: 387.5;Hofbauer cells: 630.6;Mast cells: 822.1;Megakaryocyte progenitors: 438.5;Megakaryocyte-Erythroid progenitors: 473.9;Microglia: 1141.1" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 1593.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026436, HPA026451, HPA026501" Approved Supported "Nuclear speckles" NA NA "Cluster 18: Lymphoid tissue - Immune response" "Cluster 39: Astrocytes - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 42 "Nuclear speckles" "HPA026436: , HPA026451: , HPA026501: " "unprognostic (1.86e-1)" "unprognostic (3.60e-1)" "unprognostic (2.15e-1)" "unprognostic (5.09e-2)" "unprognostic (1.55e-1)" "unprognostic (1.80e-1)" "unprognostic (3.41e-1)" "unprognostic (8.79e-2)" "unprognostic (1.43e-2)" "unprognostic (3.93e-3)" "potential prognostic favorable (6.29e-4)" "unprognostic (3.73e-1)" "unprognostic (6.90e-2)" "unprognostic (1.73e-3)" "unprognostic (1.42e-1)" "unprognostic (1.80e-1)" "potential prognostic unfavorable (4.20e-4)" "unprognostic (4.53e-1)" "unprognostic (3.85e-2)" "unprognostic (5.34e-2)" "unprognostic (1.47e-1)" "unprognostic (2.37e-1)" "unprognostic (1.73e-1)" "unprognostic (1.71e-2)" "unprognostic (8.94e-3)" "unprognostic (8.83e-2)" "unprognostic (1.04e-1)" "unprognostic (4.32e-2)" "unprognostic (2.73e-2)" "unprognostic (1.45e-2)" "unprognostic (5.59e-2)" BMP3 ENSG00000152785 "Bone morphogenetic protein 3" P12645 4 81030708-81057627 "Plasma proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 8.3;lung: 5.1;ovary: 5.1;urinary bladder: 8.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 26.9;Colonocytes: 55.1;Enteric transient amplifying cells: 21.4;Enterocytes: 28.1;Ependymal cells: 39.6;Lacrimal acinar cells: 20.8;Ocular epithelial cells: 21.8;Paneth cells: 23.2;Papillary tip epithelial cells: 42.9;Prostatic club cells: 24.6;Respiratory ciliated cells: 18.7;Respiratory secretory cells: 22.6;Salivary duct cells: 37.8;Transitional alveolar cells: 23.4;Urothelial cells: 40.7" "Cell type enhanced" "Detected in many" "ependymal cell: 44.1" "Cancer enhanced" "Detected in some" "Bladder Urothelial Carcinoma (TCGA): 9.9;Lung Adenocarcinoma (TCGA): 7.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 2.9;lymphoma: 6.6" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted in other tissues" Cytokine NA NA "Cluster 77: Intestine - Digestion" "Cluster 17: Choroid plexus - Cilium" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" "unprognostic (2.49e-3)" "potential prognostic favorable (3.35e-4)" "unprognostic (3.25e-1)" "unprognostic (9.76e-3)" "unprognostic (2.41e-1)" "unprognostic (3.49e-1)" "unprognostic (4.41e-2)" "unprognostic (4.98e-2)" "unprognostic (2.13e-1)" "unprognostic (6.87e-3)" "unprognostic (3.63e-2)" BMP4 BMP2B ENSG00000125378 "Bone morphogenetic protein 4" P12644 14 53949736-53958761 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Cancer-related genes, Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 74.6" "Cell type enriched" "Detected in many" 6 "Retinal pigment epithelial cells: 289.9" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 19.4;fibroblast: 26.8" "Cancer enhanced" "Detected in all" "Rectum Adenocarcinoma (TCGA): 83.8" "Region enriched" "Detected in all" 6 "choroid plexus: 65.3" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 1.9" "Group enriched" "Detected in many" 12 "monocytes: 1.9;T-cells: 1.3" "Cancer enhanced" "Detected in many" "colorectal cancer: 279.2" "Adrenal gland - Adrenal cortex cells, Breast - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006863, HPA066235" Uncertain "Secreted to blood" Cytokine NA NA 162000000 5800 "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" 35 "CAB006863: , HPA066235: " "unprognostic (1.22e-1)" "unprognostic (1.73e-1)" "unprognostic (8.28e-3)" "unprognostic (1.52e-1)" "unprognostic (2.86e-1)" "unprognostic (3.28e-1)" "unprognostic (3.98e-2)" "potential prognostic favorable (3.49e-5)" "unprognostic (2.25e-1)" "unprognostic (2.01e-2)" "potential prognostic favorable (3.70e-4)" "unprognostic (1.79e-3)" "unprognostic (1.41e-1)" "unprognostic (2.60e-2)" "unprognostic (2.21e-2)" "unprognostic (2.33e-1)" "unprognostic (1.14e-1)" "unprognostic (1.25e-1)" "unprognostic (3.12e-1)" "unprognostic (6.04e-2)" "unprognostic (1.13e-2)" "potential prognostic unfavorable (3.10e-4)" "unprognostic (3.03e-1)" "unprognostic (1.01e-1)" "unprognostic (5.51e-2)" "unprognostic (3.37e-1)" "unprognostic (3.56e-3)" "unprognostic (7.65e-3)" "unprognostic (1.49e-1)" "unprognostic (3.57e-1)" "unprognostic (3.06e-1)" BMP5 ENSG00000112175 "Bone morphogenetic protein 5" P22003 6 55753653-55875590 "Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "placenta: 66.9" "Cell type enhanced" "Detected in some" "Adipocytes: 54.1;Fibro-adipogenic progenitors: 283.1;Fibroblasts: 62.5;Hepatic stellate cells: 19.4;Pancreatic islet cells: 70.4;Pericytes: 88.4;Vascular smooth muscle cells: 56.7" "Cell type enriched" "Detected in some" 5 "fibroblast: 354.8" "Cancer enhanced" "Detected in some" "Lung Adenocarcinoma (TCGA): 5.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 15.3" "Liver - Hepatic stellate cells, Lung - Fibroblasts_1, Pituitary gland - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted - unknown location" Cytokine NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 49: Hindbrain - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 108: Fibroblasts - ECM organization" "unprognostic (4.04e-1)" "unprognostic (8.35e-3)" "unprognostic (1.32e-1)" "unprognostic (1.37e-1)" "potential prognostic favorable (4.67e-5)" "unprognostic (1.69e-1)" "potential prognostic unfavorable (8.96e-4)" "unprognostic (1.87e-1)" "unprognostic (2.46e-1)" "unprognostic (2.79e-1)" "unprognostic (3.02e-1)" "unprognostic (2.11e-1)" BMP6 "VGR, VGR1" ENSG00000153162 "Bone morphogenetic protein 6" P22004 6 7726099-7881728 "Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 19.2" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 96.0;Hematopoietic stem cells: 125.7;Loop of henle epithelial cells: 110.3;Neutrophils: 156.4;Oocytes: 170.4;Pituitary stem cells: 363.7;Plasma cells: 349.3;Platelets: 343.8;Undifferentiated spermatogonia: 81.3;Vascular endothelial cells: 163.6" "Group enriched" "Detected in many" 4 "endothelial cell: 361.6;fibroblast: 404.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Lineage enriched" "Detected in single" 11 "granulocytes: 1.1" "Cancer enhanced" "Detected in many" "Myeloma: 42.2;Rhabdoid: 30.5" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Minor Salivary Gland - Plasma cells, Skeletal muscle - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB002773, HPA062683" Approved Approved Mitochondria "Secreted to blood" Cytokine No No 4970000 57000 "Cluster 46: Basophils - Proteolysis" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 2 Mitochondria "CAB002773: , HPA062683: " "unprognostic (9.89e-2)" "unprognostic (1.75e-2)" "unprognostic (7.47e-2)" "unprognostic (1.67e-1)" "unprognostic (2.08e-1)" "unprognostic (2.40e-1)" "unprognostic (5.77e-3)" "unprognostic (1.07e-1)" "unprognostic (4.37e-1)" "potential prognostic favorable (7.51e-7)" "unprognostic (6.05e-3)" "unprognostic (1.45e-1)" "unprognostic (1.78e-2)" "unprognostic (1.17e-1)" "potential prognostic favorable (8.17e-5)" "unprognostic (5.47e-2)" "unprognostic (2.79e-1)" "unprognostic (4.42e-2)" "unprognostic (2.39e-2)" "unprognostic (4.83e-2)" "unprognostic (1.65e-1)" "unprognostic (2.57e-1)" "unprognostic (2.05e-1)" "unprognostic (2.23e-2)" "unprognostic (1.82e-2)" "unprognostic (6.07e-2)" "unprognostic (1.79e-1)" "unprognostic (1.89e-2)" BMP7 OP-1 ENSG00000101144 "Bone morphogenetic protein 7" P18075 20 57168753-57266641 "Predicted intracellular proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 34.2;thyroid gland: 43.0" "Cell type enhanced" "Detected in many" "Astrocytes: 112.8;Basal keratinocytes: 73.0;Bergmann glia: 73.9;Choroid plexus epithelial cells: 164.3;Cytotrophoblasts: 219.6;Ependymal cells: 150.0;Esophageal basal cells: 83.6;Migrating cytotrophoblasts: 122.7;Ocular epithelial cells: 82.7;Oligodendrocyte progenitor cells: 146.8;Podocytes: 103.2;Retinal pigment epithelial cells: 362.4" "Cell type enhanced" "Detected in many" "astrocyte: 132.9;choroid plexus epithelial cell: 133.8;ependymal cell: 162.4;oligodendrocyte precursor cell: 166.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Kidney - Podocytes, Minor Salivary Gland - Minor salivary gland basal cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061339 Approved Nucleoplasm,Vesicles "Secreted to blood" Cytokine NA NA 248000 "Cluster 33: Thyroid gland - Tissue development" "Cluster 39: Astrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 23 Vesicles Nucleoplasm "HPA061339: " "unprognostic (1.10e-1)" "unprognostic (1.98e-1)" "unprognostic (2.93e-3)" "unprognostic (4.09e-2)" "unprognostic (2.57e-1)" "unprognostic (8.51e-2)" "unprognostic (2.18e-1)" "unprognostic (1.21e-1)" "unprognostic (1.51e-1)" "unprognostic (3.27e-2)" "unprognostic (1.39e-1)" "unprognostic (4.37e-2)" "unprognostic (1.11e-1)" "unprognostic (7.38e-2)" "unprognostic (1.79e-2)" "unprognostic (7.92e-3)" "unprognostic (1.45e-1)" "unprognostic (7.08e-2)" "unprognostic (6.12e-2)" "unprognostic (3.78e-2)" "unprognostic (4.33e-1)" "unprognostic (3.13e-1)" "unprognostic (1.21e-1)" "unprognostic (1.74e-1)" "unprognostic (1.29e-1)" "unprognostic (9.72e-3)" "unprognostic (2.70e-1)" BMP8A OP-2 ENSG00000183682 "Bone morphogenetic protein 8a" Q7Z5Y6 1 39491636-39529869 "Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 7 "thyroid gland: 85.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 27.2;Early spermatids: 78.3;Epicardial cells: 93.2;Epididymal clear cells: 26.5;Late spermatids: 319.6" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 30.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 8.2;prostate cancer: 7.3" "Skin - Inner root sheath cells" HPA047254 Approved Vesicles "Secreted to blood" Cytokine NA NA "Cluster 33: Thyroid gland - Tissue development" "Cluster 30: White matter - Myelination" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 11 Vesicles "HPA047254: " "unprognostic (4.73e-2)" "unprognostic (1.47e-2)" "unprognostic (6.95e-2)" "unprognostic (1.08e-1)" "unprognostic (3.85e-2)" "unprognostic (4.40e-1)" "unprognostic (5.05e-1)" "unprognostic (4.38e-1)" "unprognostic (2.27e-1)" "potential prognostic unfavorable (9.44e-4)" "unprognostic (2.92e-2)" "unprognostic (3.01e-2)" "unprognostic (2.11e-2)" "unprognostic (7.17e-2)" "potential prognostic unfavorable (4.24e-4)" "unprognostic (9.55e-2)" "unprognostic (1.11e-2)" "unprognostic (5.32e-2)" "unprognostic (3.02e-2)" "unprognostic (2.37e-1)" "unprognostic (1.76e-1)" "unprognostic (3.73e-1)" "unprognostic (4.26e-2)" "unprognostic (2.28e-2)" "unprognostic (1.08e-2)" "unprognostic (1.67e-1)" "unprognostic (4.14e-3)" "unprognostic (3.65e-2)" BMP8B "BMP8, OP-2" ENSG00000116985 "Bone morphogenetic protein 8b" P34820 1 39757182-39788865 "Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Early spermatids: 139.5;Late spermatids: 170.1" "Group enriched" "Detected in many" 4 "committed oligodendrocyte precursor: 19.8;oligodendrocyte precursor cell: 14.7" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 13.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 38.6" "Adrenal gland - Adrenal medulla cells" HPA047254 Approved Vesicles "Secreted to blood" Cytokine NA NA "Cluster 60: Stomach - Digestion" "Cluster 11: White matter - Signal transduction" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 44: Plasma cells - Antibody production & secretion" 8 Vesicles "HPA047254: " "unprognostic (1.40e-1)" "unprognostic (2.12e-3)" "unprognostic (6.28e-1)" "unprognostic (6.11e-2)" "unprognostic (2.02e-2)" "unprognostic (1.80e-1)" "unprognostic (2.76e-1)" "unprognostic (1.25e-2)" "unprognostic (3.24e-2)" "unprognostic (1.38e-1)" "unprognostic (3.94e-1)" "unprognostic (5.02e-2)" "unprognostic (7.55e-2)" "unprognostic (1.28e-1)" "unprognostic (2.56e-1)" "unprognostic (1.06e-1)" "unprognostic (1.06e-2)" "unprognostic (9.61e-2)" "unprognostic (7.75e-2)" "unprognostic (3.12e-1)" "unprognostic (2.69e-2)" "potential prognostic unfavorable (2.20e-5)" "unprognostic (9.46e-2)" "unprognostic (3.15e-1)" "unprognostic (2.42e-1)" "unprognostic (2.02e-1)" "unprognostic (7.10e-3)" "unprognostic (1.95e-3)" BMPER "CRIM3, Cv2" ENSG00000164619 "BMP binding endothelial regulator" Q8N8U9 7 33904308-34156427 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 177.2;Adrenal medulla cells: 127.6;Brain excitatory neurons: 202.7;Fibro-adipogenic progenitors: 496.9;Gonadotrophs: 532.0;Oligodendrocyte progenitor cells: 130.3;Oligodendrocytes: 267.6;Somatotrophs: 210.9;Thyrotrophs: 313.5" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 1271.3" "Cancer enhanced" "Detected in single" "Glioblastoma Multiforme (TCGA): 3.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 11.5" "Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" "No annotated function" NA NA 6500 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 37: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" "unprognostic (1.03e-1)" "unprognostic (2.66e-1)" "unprognostic (3.58e-1)" "unprognostic (5.92e-2)" BMPR1A "ACVRLK3, ALK3, CD292" ENSG00000107779 "Bone morphogenetic protein receptor type 1A" P36894 10 86756601-86932825 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 587.2;Myonuclei: 857.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB019398 Approved Approved Cytosol NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" 47 Cytosol "CAB019398: " "unprognostic (4.53e-3)" "unprognostic (3.26e-2)" "unprognostic (8.39e-3)" "unprognostic (2.82e-1)" "unprognostic (3.15e-2)" "unprognostic (5.05e-2)" "unprognostic (1.64e-3)" "potential prognostic favorable (5.70e-5)" "unprognostic (2.37e-1)" "unprognostic (1.26e-3)" "unprognostic (2.56e-3)" "unprognostic (7.22e-2)" "unprognostic (5.16e-2)" "unprognostic (3.05e-3)" "unprognostic (1.88e-1)" "unprognostic (4.24e-1)" "unprognostic (2.76e-1)" "unprognostic (1.59e-1)" "unprognostic (5.14e-2)" "unprognostic (3.46e-2)" "unprognostic (5.84e-2)" "unprognostic (1.69e-1)" "unprognostic (3.22e-2)" "unprognostic (5.56e-2)" "unprognostic (1.60e-1)" "unprognostic (2.34e-3)" "unprognostic (2.51e-2)" "unprognostic (4.92e-2)" "unprognostic (2.09e-1)" "unprognostic (2.64e-3)" "unprognostic (2.74e-2)" BMPR1B "ALK6, CDw293" ENSG00000138696 "Bone morphogenetic protein receptor type 1B" O00238 4 94757955-95158448 "CD markers, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Chondrogenesis "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 23.2;prostate: 21.0" "Cell type enhanced" "Detected in many" "Astrocytes: 723.5;Bergmann glia: 1242.3;Ependymal cells: 504.6;Prostatic glandular cells: 2574.7;Renal collecting duct intercalated cells: 729.7;Renal collecting duct principal cells: 886.0;Renal connecting tubule cells: 669.5;Respiratory basal cells: 474.0;Respiratory deuterosomal cells: 611.6;Respiratory secretory cells: 688.0" "Group enriched" "Detected in all" 5 "astrocyte: 814.4;Bergmann glia: 1335.1;ependymal cell: 596.0" "Group enriched" "Detected in many" 5 "Breast Invasive Carcinoma (TCGA): 70.4;Kidney Chromophobe (TCGA): 41.1;Prostate Adenocarcinoma (TCGA): 39.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 14.0" "Adipose subcutaneous - Smooth muscle cells, Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Stomach - Parietal cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 65: Brain - Transcription" "Cluster 39: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 6 "unprognostic (2.56e-3)" "unprognostic (2.40e-1)" "unprognostic (2.75e-1)" "unprognostic (2.96e-2)" "unprognostic (4.05e-2)" "unprognostic (6.74e-2)" "unprognostic (1.52e-1)" "unprognostic (1.88e-1)" "unprognostic (9.63e-2)" "unprognostic (3.94e-3)" "unprognostic (1.36e-2)" "unprognostic (1.39e-2)" "unprognostic (2.06e-1)" "unprognostic (1.50e-1)" "unprognostic (1.79e-2)" "unprognostic (1.01e-1)" "unprognostic (1.95e-1)" "unprognostic (9.62e-2)" "unprognostic (2.94e-3)" "unprognostic (3.31e-1)" "unprognostic (1.07e-1)" "unprognostic (7.86e-2)" "unprognostic (7.69e-3)" "unprognostic (9.69e-2)" "unprognostic (1.77e-2)" BMPR2 "BMPR-II, BMPR3, BRK-3, PPH1, T-ALK" ENSG00000204217 "Bone morphogenetic protein receptor type 2" Q13873 2 202376327-202567751 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Vascular endothelial cells: 1029.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Lung - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells, Thyroid gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017385, HPA049014" Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 1: Neurons - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 14 "Nucleoplasm, Plasma membrane" "HPA017385: , HPA049014: " "unprognostic (3.74e-2)" "unprognostic (1.56e-1)" "unprognostic (2.13e-1)" "unprognostic (3.85e-2)" "unprognostic (2.23e-1)" "unprognostic (1.78e-2)" "unprognostic (2.74e-1)" "unprognostic (9.97e-2)" "unprognostic (2.05e-1)" "unprognostic (2.24e-2)" "validated prognostic favorable (4.24e-6)" "validated prognostic favorable (2.41e-4)" "unprognostic (7.09e-2)" "unprognostic (1.21e-2)" "unprognostic (3.84e-1)" "unprognostic (3.54e-1)" "unprognostic (6.34e-2)" "unprognostic (6.62e-2)" "unprognostic (3.82e-1)" "unprognostic (2.33e-2)" "unprognostic (2.15e-2)" "unprognostic (1.19e-3)" "unprognostic (2.72e-1)" "unprognostic (1.91e-1)" "unprognostic (2.25e-2)" "unprognostic (5.83e-2)" "unprognostic (2.50e-2)" "unprognostic (2.45e-2)" "unprognostic (4.96e-2)" "unprognostic (3.15e-2)" "unprognostic (4.13e-2)" BMS1 "BMS1L, KIAA0187" ENSG00000165733 "BMS1 ribosome biogenesis factor" Q14692 10 42782795-42834937 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Ribosome biogenesis" Hydrolase "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036589, HPA043081" Uncertain Enhanced "Nucleoplasm,Nucleoli,Mitotic chromosome" Yes No "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 5: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 17: Non-specific - RNA processing" 67 "Nucleoplasm, Nucleoli, Mitotic chromosome" "HPA036589: , HPA043081: " "unprognostic (2.76e-1)" "unprognostic (5.60e-3)" "unprognostic (8.31e-2)" "unprognostic (3.84e-1)" "unprognostic (2.22e-1)" "unprognostic (1.99e-1)" "unprognostic (4.44e-2)" "potential prognostic favorable (7.25e-6)" "unprognostic (2.32e-3)" "potential prognostic unfavorable (6.38e-5)" "unprognostic (1.12e-2)" "unprognostic (5.97e-3)" "unprognostic (7.59e-2)" "potential prognostic unfavorable (1.32e-6)" "unprognostic (8.81e-3)" "unprognostic (1.51e-2)" "potential prognostic unfavorable (7.50e-5)" "unprognostic (3.53e-2)" "unprognostic (1.84e-1)" "unprognostic (1.20e-1)" "unprognostic (3.92e-2)" "unprognostic (7.57e-3)" "unprognostic (2.15e-2)" "unprognostic (1.97e-2)" "unprognostic (1.87e-1)" "unprognostic (2.29e-1)" "unprognostic (6.97e-2)" "unprognostic (1.88e-1)" "unprognostic (2.85e-1)" "unprognostic (1.30e-1)" "unprognostic (7.82e-2)" BMT2 "C7orf60, DKFZp762M126, FLJ31818, SAMTOR" ENSG00000164603 "Base methyltransferase of 25S rRNA 2 homolog" Q1RMZ1 7 112819147-112939875 "Predicted intracellular proteins, Predicted membrane proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 202.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044405, HPA050733" Uncertain Approved Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 61: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 39: Non-specific - Transcription" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 2 Cytosol "HPA044405: , HPA050733: " "unprognostic (9.64e-3)" "unprognostic (1.97e-1)" "potential prognostic unfavorable (9.01e-4)" "unprognostic (1.05e-1)" "unprognostic (1.35e-1)" "unprognostic (1.27e-1)" "unprognostic (1.12e-1)" "unprognostic (1.11e-1)" "unprognostic (1.98e-3)" "potential prognostic favorable (2.47e-6)" "unprognostic (8.08e-2)" "unprognostic (3.86e-1)" "potential prognostic unfavorable (9.41e-6)" "unprognostic (4.36e-2)" "unprognostic (1.83e-1)" "unprognostic (2.54e-2)" "unprognostic (9.92e-2)" "unprognostic (1.39e-2)" "unprognostic (3.60e-3)" "unprognostic (1.24e-1)" "unprognostic (2.24e-1)" "unprognostic (1.79e-1)" "unprognostic (1.79e-2)" "unprognostic (1.40e-1)" "unprognostic (3.62e-2)" "unprognostic (8.64e-3)" "unprognostic (1.43e-1)" "unprognostic (3.88e-2)" "unprognostic (1.62e-1)" BMX "ETK, PSCTK3" ENSG00000102010 "BMX non-receptor tyrosine kinase" P51813 X 15464246-15556529 "Enzymes, Predicted intracellular proteins" "Apoptosis, Cell adhesion, Stress response" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "epididymis: 96.9" "Cell type enriched" "Detected in many" 4 "Tuft cells: 1037.5" "Cell type enriched" "Detected in many" 4 "endothelial cell: 41.4" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 5.2" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 16 "neutrophil: 7.6" "Lineage enriched" "Detected in single" 77 "granulocytes: 7.6" "Group enriched" "Detected in some" 6 "cervical cancer: 2.6;lung cancer: 4.6;prostate cancer: 2.0;skin cancer: 1.7" "Breast - Endothelial cells, Colon - Endothelial cells, Minor Salivary Gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Spleen - Neutrophils_2, Stomach - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001048, CAB032495" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 24: Non-specific - Unknown function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 14 "Plasma membrane" Nucleoplasm "CAB032495: , HPA001048: " "unprognostic (1.96e-2)" "unprognostic (5.64e-2)" "unprognostic (3.20e-1)" "potential prognostic favorable (4.88e-9)" "unprognostic (1.66e-3)" "unprognostic (1.07e-2)" "unprognostic (2.35e-1)" "unprognostic (1.92e-1)" "unprognostic (2.24e-1)" "unprognostic (9.69e-2)" "unprognostic (1.10e-1)" "unprognostic (1.69e-1)" "unprognostic (6.53e-2)" "unprognostic (2.23e-1)" "unprognostic (8.62e-2)" "unprognostic (1.75e-1)" BNC1 "BNC, HsT19447" ENSG00000169594 "Basonuclin 1" Q01954 15 83255884-83284664 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" DNA-binding "Disease variant, Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 14.2;esophagus: 12.0;testis: 23.6" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 118.7;Early spermatids: 42.0;Epicardial cells: 154.6;Epididymal basal cells: 54.3;Esophageal basal cells: 54.9;Late primary spermatocytes: 52.1;Late spermatids: 180.8;Mesothelial cells: 356.3;Ocular epithelial cells: 71.7;Suprabasal keratinocytes: 71.1" "Cell type enhanced" "Detected in some" "pericyte: 1.9" "Group enriched" "Detected in many" 4 "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 19.1;Head and Neck Squamous Cell Carcinoma (TCGA): 37.9;Lung Squamous Cell Carcinoma (TCGA): 13.0;Testicular Germ Cell Tumor (TCGA): 15.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 29.8" "Adipose visceral - Mesothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Minor salivary gland basal cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA063183, HPA077428" Enhanced Nucleoplasm NA NA "Cluster 39: Testis - Nuclear processes" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 26: Keratinocytes - Keratinization" 2 Nucleoplasm "HPA063183: , HPA077428: " "unprognostic (3.74e-2)" "unprognostic (2.65e-1)" "unprognostic (1.58e-1)" "unprognostic (7.72e-2)" "unprognostic (1.93e-2)" "unprognostic (2.45e-1)" "unprognostic (5.13e-2)" "potential prognostic unfavorable (4.10e-4)" "unprognostic (4.01e-2)" "unprognostic (2.45e-1)" "unprognostic (4.19e-3)" BNC2 "BSN2, FLJ20043" ENSG00000173068 "Basonuclin 2" Q6ZN30 9 16409503-16870843 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 28.7;ovary: 27.6;smooth muscle: 33.1" "Cell type enhanced" "Detected in many" "Adipocytes: 591.7;Epicardial cells: 1071.1;Fibro-adipogenic progenitors: 1047.9;Leydig cells: 1048.9;Mast cells: 528.0;Melanocytes: 526.7;Mesothelial cells: 1825.6;Microglia: 767.8;Myonuclei: 514.3;Ovarian stromal cells: 1039.3;Peritubular myoid cells: 578.5;Pituitary stem cells: 727.4;Proximal tubule cells: 1190.8" "Group enriched" "Detected in many" 4 "central nervous system macrophage: 1021.7;endothelial cell: 332.7;fibroblast: 990.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "gdT-cell: 2.5" "Lineage enriched" "Detected in single" 5 "T-cells: 2.5" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Fibroblasts, Breast - Fibroblasts, Heart muscle - Fibroblasts, Lung - Fibroblasts_2, Pancreas - Fibroblasts, Prostate - Smooth muscle cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA018525, HPA077461" Approved Supported "Nucleoli fibrillar center,Nuclear bodies" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 94: Gonadal somatic cells - Mixed function" 1 "Nucleoli fibrillar center" "Nuclear bodies" "HPA018525: , HPA077461: " "unprognostic (5.74e-2)" "unprognostic (1.30e-1)" "unprognostic (1.69e-1)" "unprognostic (1.39e-1)" "unprognostic (4.72e-2)" "unprognostic (2.22e-1)" "unprognostic (3.85e-2)" "unprognostic (3.37e-2)" "unprognostic (8.51e-2)" "unprognostic (1.67e-1)" "unprognostic (3.52e-3)" "unprognostic (2.21e-1)" "unprognostic (3.19e-1)" "unprognostic (2.01e-1)" "unprognostic (1.17e-2)" "unprognostic (2.31e-1)" "unprognostic (2.79e-1)" "unprognostic (2.16e-1)" "unprognostic (3.37e-1)" "unprognostic (1.03e-1)" "unprognostic (2.53e-1)" "unprognostic (6.70e-2)" "unprognostic (1.94e-2)" "unprognostic (1.48e-2)" "unprognostic (1.15e-2)" "unprognostic (4.88e-2)" "unprognostic (4.37e-2)" "unprognostic (4.98e-2)" BNIP1 "Nip1, SEC20" ENSG00000113734 "BCL2 interacting protein 1" Q12981 5 173144442-173164387 "Essential proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, ER-Golgi transport, Host-virus interaction, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 50.9;Oocytes: 78.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008009, HPA008149" Supported Supported "Endoplasmic reticulum" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 45: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 41: Oocytes - Oogenesis" 72 "Endoplasmic reticulum" "HPA008009: , HPA008149: " "unprognostic (5.42e-3)" "unprognostic (4.06e-2)" "unprognostic (2.30e-3)" "unprognostic (8.67e-3)" "unprognostic (1.59e-1)" "potential prognostic favorable (8.50e-4)" "unprognostic (3.17e-1)" "unprognostic (1.90e-1)" "unprognostic (1.62e-2)" "unprognostic (8.24e-3)" "unprognostic (2.06e-1)" "unprognostic (2.55e-1)" "unprognostic (2.55e-2)" "unprognostic (1.12e-3)" "unprognostic (3.89e-3)" "unprognostic (4.64e-2)" "unprognostic (2.33e-1)" "unprognostic (6.11e-2)" "unprognostic (2.53e-1)" "unprognostic (1.78e-1)" "unprognostic (1.71e-2)" "unprognostic (6.61e-2)" "unprognostic (1.61e-2)" "unprognostic (3.21e-1)" "unprognostic (1.73e-1)" "unprognostic (6.35e-2)" "unprognostic (8.90e-2)" "unprognostic (1.09e-1)" "unprognostic (1.64e-1)" "unprognostic (2.66e-2)" "unprognostic (1.32e-1)" BNIP2 "BNIP-2, Nip2" ENSG00000140299 "BCL2 interacting protein 2" Q12982 15 59659146-59689339 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 122.0" "Cell type enhanced" "Detected in many" "Neutrophil progenitors: 168.6;Neutrophils: 264.2;Platelets: 194.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026843 Approved Supported Nucleoli,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 44: Non-specific - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 41 Cytosol Nucleoli "HPA026843: " "unprognostic (9.68e-2)" "unprognostic (8.46e-2)" "unprognostic (3.24e-2)" "unprognostic (4.29e-2)" "unprognostic (9.21e-3)" "unprognostic (4.54e-2)" "unprognostic (3.19e-1)" "unprognostic (1.87e-1)" "unprognostic (1.22e-1)" "unprognostic (2.54e-1)" "potential prognostic favorable (1.64e-4)" "unprognostic (1.32e-2)" "unprognostic (1.08e-1)" "unprognostic (9.93e-2)" "unprognostic (1.15e-1)" "unprognostic (3.16e-1)" "unprognostic (3.18e-3)" "unprognostic (6.39e-2)" "unprognostic (2.31e-1)" "unprognostic (1.05e-2)" "unprognostic (5.79e-2)" "unprognostic (1.05e-2)" "potential prognostic unfavorable (8.63e-5)" "unprognostic (1.30e-2)" "unprognostic (7.61e-2)" "unprognostic (1.14e-2)" "unprognostic (5.16e-1)" "unprognostic (6.06e-3)" "unprognostic (2.12e-1)" "unprognostic (4.64e-2)" "unprognostic (4.16e-2)" BNIP3 "HABON, Nip3" ENSG00000176171 "BCL2 interacting protein 3" Q12983 10 131967684-131981967 "Cancer-related genes, Predicted membrane proteins, Transporters" "Apoptosis, Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 530.0;skeletal muscle: 333.5" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 1326.3;Extravillous trophoblasts: 673.2;Hepatocytes: 478.4;Pancreatic acinar cells: 920.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003015, CAB011676" Supported NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 70: Non-specific - Protein processing" "Cluster 27: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 65 "CAB011676: , HPA003015: " "potential prognostic unfavorable (1.23e-4)" "potential prognostic unfavorable (7.92e-4)" "unprognostic (2.81e-1)" "potential prognostic unfavorable (1.82e-4)" "unprognostic (7.25e-2)" "unprognostic (6.17e-2)" "unprognostic (2.09e-2)" "unprognostic (1.83e-1)" "potential prognostic unfavorable (5.47e-4)" "potential prognostic unfavorable (1.46e-4)" "potential prognostic favorable (8.69e-7)" "unprognostic (4.47e-2)" "unprognostic (2.67e-2)" "unprognostic (4.38e-2)" "unprognostic (1.22e-1)" "unprognostic (3.54e-2)" "unprognostic (7.29e-3)" "unprognostic (1.61e-1)" "unprognostic (1.75e-1)" "unprognostic (2.07e-1)" "unprognostic (8.06e-3)" "unprognostic (1.34e-1)" "unprognostic (1.60e-2)" "unprognostic (2.11e-2)" "unprognostic (1.14e-1)" "unprognostic (2.55e-3)" "unprognostic (1.20e-1)" "unprognostic (2.34e-2)" "unprognostic (1.03e-1)" "unprognostic (3.98e-2)" "unprognostic (1.12e-1)" BNIP3L "BNIP3a, Nix" ENSG00000104765 "BCL2 interacting protein 3 like" O60238 8 26383054-26505636 "Cancer-related genes, Predicted membrane proteins, Transporters" "Apoptosis, Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial glandular cells: 868.3;Erythrocytes: 671.1;Esophageal apical cells: 915.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015652, CAB025371" Enhanced Supported "Nuclear speckles,Mitochondria" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 40: Non-specific - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 51: Secretory epithelial cells - Mixed function" 28 Mitochondria "Nuclear speckles" "CAB025371: , HPA015652: " "unprognostic (8.45e-2)" "unprognostic (8.10e-2)" "unprognostic (2.10e-1)" "unprognostic (2.56e-1)" "unprognostic (1.71e-1)" "unprognostic (2.53e-2)" "unprognostic (9.13e-3)" "unprognostic (6.29e-2)" "unprognostic (1.21e-1)" "unprognostic (1.91e-3)" "potential prognostic favorable (8.46e-8)" "unprognostic (1.19e-3)" "unprognostic (1.24e-1)" "potential prognostic unfavorable (6.57e-4)" "unprognostic (3.73e-2)" "unprognostic (1.84e-2)" "unprognostic (4.41e-2)" "unprognostic (1.90e-1)" "unprognostic (2.55e-2)" "unprognostic (3.18e-1)" "potential prognostic unfavorable (5.90e-4)" "unprognostic (1.23e-2)" "unprognostic (2.08e-2)" "unprognostic (2.01e-1)" "unprognostic (3.58e-1)" "unprognostic (2.19e-1)" "unprognostic (1.49e-1)" "unprognostic (7.27e-3)" "unprognostic (4.09e-1)" "unprognostic (2.98e-3)" "unprognostic (1.50e-1)" BNIP5 "C6orf222, DKFZp779B1540" ENSG00000189325 "BCL2 interacting protein 5" P0C671 6 36315761-36336888 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "intestine: 23.2" "Cell type enhanced" "Detected in some" "Colonocytes: 422.2;Enteric stem cells: 93.0;Enterocytes: 851.4;Foveolar cells: 142.5;Goblet cells: 303.1;Neuroendocrine cells: 91.2;Paneth cells: 170.2;Tuft cells: 242.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Colon Adenocarcinoma (TCGA): 12.7;Pancreatic Adenocarcinoma (TCGA): 7.1;Rectum Adenocarcinoma (TCGA): 12.5;Stomach Adenocarcinoma (TCGA): 11.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 3.4" "Colon - Colon enterocytes, Pancreas - Ductal cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA038407, HPA058189" Uncertain Approved Cytosol NA NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 7 Cytosol "HPA038407: , HPA058189: " "unprognostic (1.67e-1)" "unprognostic (5.23e-2)" "unprognostic (2.81e-1)" "unprognostic (2.10e-2)" "unprognostic (9.50e-2)" "unprognostic (9.09e-2)" "unprognostic (1.70e-3)" "unprognostic (1.11e-2)" "unprognostic (6.40e-2)" BNIPL "BNIP-S, BNIP-Salpha, BNIP-Sbeta, BNIPl-1, BNIPL-2, PP753" ENSG00000163141 "BCL2 interacting protein like" Q7Z465 1 151036321-151047720 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "cervix: 50.4;esophagus: 118.3;skin 1: 170.9;vagina: 64.5" "Group enriched" "Detected in many" 5 "Esophageal apical cells: 1259.0;Esophageal suprabasal cells: 350.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Skin - Keratinocyte (other)" "Group enriched" "Detected in some" 9 "basal ganglia: 1.6;cerebellum: 2.4" "Low region specificity" "Detected in many" HPA019946 Uncertain Cytosol NA NA "Cluster 58: Skin - Keratinization" "Cluster 15: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 3 Cytosol "HPA019946: " "unprognostic (2.59e-1)" "unprognostic (1.07e-2)" "unprognostic (8.03e-2)" "unprognostic (2.56e-2)" "unprognostic (1.16e-1)" "unprognostic (2.41e-1)" "unprognostic (3.89e-2)" "unprognostic (2.94e-2)" "unprognostic (2.46e-2)" "unprognostic (2.32e-2)" "unprognostic (2.32e-1)" "unprognostic (1.67e-1)" "unprognostic (8.44e-2)" "unprognostic (1.88e-1)" "unprognostic (4.39e-2)" "unprognostic (1.68e-1)" "unprognostic (1.07e-1)" "unprognostic (7.58e-2)" "unprognostic (6.45e-2)" "unprognostic (1.14e-3)" "unprognostic (8.60e-2)" BOC "Boi, CDON2" ENSG00000144857 "BOC cell adhesion associated, oncogene regulated" Q9BWV1 3 113211003-113287459 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bergmann glia: 146.4;Choroid plexus epithelial cells: 125.3;Ependymal cells: 186.0;Fibro-adipogenic progenitors: 394.2;Leydig cells: 186.7;Mesothelial cells: 140.9;Pituicytes/FSCs: 645.9;Pituitary stem cells: 435.7;Retinal pigment epithelial cells: 225.9;Smooth muscle cells: 146.1" "Cell type enhanced" "Detected in many" "astrocyte: 186.4;Bergmann glia: 168.7;ependymal cell: 208.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Heart muscle - Fibroblasts, Lung - Fibroblasts_2, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025806 Uncertain Supported "Nucleoplasm,Nuclear bodies,Plasma membrane" "Intracellular and membrane" "Cell adhesion" NA No 1500000 "Cluster 75: Ovary - Mixed function" "Cluster 44: Non-specific - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 2 "Nuclear bodies, Plasma membrane" Nucleoplasm "CAB025806: " "unprognostic (2.79e-2)" "unprognostic (1.73e-2)" "unprognostic (2.37e-1)" "unprognostic (1.31e-2)" "unprognostic (2.67e-2)" "unprognostic (1.87e-2)" "unprognostic (1.71e-1)" "unprognostic (8.29e-2)" "potential prognostic favorable (9.96e-4)" "unprognostic (1.45e-1)" "potential prognostic favorable (3.45e-6)" "unprognostic (1.43e-3)" "unprognostic (3.14e-2)" "unprognostic (1.90e-2)" "unprognostic (1.78e-1)" "unprognostic (2.58e-1)" "unprognostic (7.69e-2)" "unprognostic (7.96e-2)" "unprognostic (1.42e-3)" "unprognostic (1.65e-1)" "unprognostic (6.64e-2)" "unprognostic (6.74e-2)" "unprognostic (5.88e-2)" "unprognostic (1.01e-2)" "unprognostic (3.51e-2)" "unprognostic (7.61e-2)" "unprognostic (1.23e-2)" "unprognostic (2.51e-1)" "unprognostic (1.49e-1)" "unprognostic (1.93e-1)" BOD1 FAM44B ENSG00000145919 "Biorientation of chromosomes in cell division 1" Q96IK1 5 173607145-173616659 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 160.2;Late spermatids: 212.2;Oocytes: 202.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA036293 Uncertain NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 15: Non-specific - Protein processing" 5 "HPA036293: " "unprognostic (3.17e-2)" "unprognostic (2.24e-1)" "unprognostic (2.38e-3)" "unprognostic (2.15e-2)" "unprognostic (2.28e-1)" "unprognostic (2.34e-2)" "unprognostic (4.65e-1)" "unprognostic (4.09e-1)" "unprognostic (3.19e-3)" "unprognostic (1.36e-2)" "potential prognostic favorable (1.47e-6)" "unprognostic (1.95e-2)" "unprognostic (2.01e-1)" "validated prognostic unfavorable (1.08e-5)" "validated prognostic unfavorable (4.09e-5)" "unprognostic (3.22e-1)" "unprognostic (5.01e-2)" "unprognostic (2.37e-1)" "unprognostic (2.10e-1)" "unprognostic (1.05e-1)" "unprognostic (7.67e-2)" "unprognostic (1.28e-1)" "potential prognostic unfavorable (1.68e-6)" "unprognostic (2.74e-1)" "potential prognostic favorable (2.82e-4)" "unprognostic (4.14e-1)" "unprognostic (3.38e-2)" "unprognostic (1.70e-1)" "unprognostic (7.66e-2)" "unprognostic (4.70e-2)" "unprognostic (1.22e-1)" BOD1L1 "BOD1L, FAM44A, FLJ33215, KIAA1327" ENSG00000038219 "Biorientation of chromosomes in cell division 1 like 1" Q8NFC6 4 13568738-13627725 "Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 912.9;Sertoli cells: 428.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 8.4" "Lineage enriched" "Detected in many" 5 "granulocytes: 8.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036943, HPA037362, HPA041290" Approved Approved Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 18 Nucleoplasm "HPA036943: , HPA037362: , HPA041290: " "unprognostic (4.35e-2)" "unprognostic (1.09e-1)" "unprognostic (4.96e-2)" "unprognostic (1.41e-1)" "unprognostic (7.66e-3)" "unprognostic (1.46e-1)" "unprognostic (3.24e-2)" "unprognostic (7.10e-2)" "unprognostic (3.93e-1)" "validated prognostic favorable (4.72e-5)" "validated prognostic favorable (3.51e-4)" "unprognostic (1.48e-1)" "unprognostic (3.52e-2)" "unprognostic (5.40e-3)" "unprognostic (2.70e-2)" "unprognostic (3.06e-1)" "unprognostic (2.92e-1)" "unprognostic (1.13e-1)" "unprognostic (3.14e-1)" "unprognostic (7.09e-2)" "unprognostic (1.90e-2)" "unprognostic (2.44e-2)" "unprognostic (2.98e-2)" "unprognostic (1.21e-2)" "unprognostic (1.25e-1)" "unprognostic (2.39e-1)" "unprognostic (1.78e-1)" "unprognostic (1.95e-2)" "unprognostic (3.89e-2)" BOD1L2 "BOD1P, FAM44C, MGC33608" ENSG00000228075 "Biorientation of chromosomes in cell division 1 like 2" Q8IYS8 18 57147087-57150410 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1044 "testis: 253.7" "Cell type enriched" "Detected in some" 4 "Late spermatids: 8773.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" HPA036293 Uncertain NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 4 "HPA036293: " BOK "BCL2L9, BOKL, MGC4631" ENSG00000176720 "BCL2 family apoptosis regulator BOK" Q9UMX3 2 241551424-241574131 "Plasma proteins, Predicted membrane proteins, Transporters" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 116.2;liver: 95.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 65.1;Epididymal principal cells: 45.9;Esophageal apical cells: 75.9;Esophageal suprabasal cells: 63.0;Hepatocytes: 122.1;Oligodendrocytes: 80.1" "Group enriched" "Detected in many" 5 "committed oligodendrocyte precursor: 41.9;oligodendrocyte: 99.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.3" "Lineage enhanced" "Detected in single" "T-cells: 2.3" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Spleen - Fibroblasts_1, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 72: Neuronal - Signal transduction" "Cluster 80: Oligodendrocytes - Myelination" 5 "unprognostic (4.96e-3)" "unprognostic (4.71e-2)" "unprognostic (3.29e-1)" "unprognostic (4.12e-3)" "unprognostic (4.85e-2)" "unprognostic (5.57e-2)" "unprognostic (2.50e-1)" "unprognostic (6.00e-2)" "unprognostic (6.27e-2)" "unprognostic (4.15e-2)" "potential prognostic favorable (2.55e-6)" "unprognostic (8.24e-3)" "potential prognostic favorable (9.08e-5)" "unprognostic (5.00e-3)" "potential prognostic favorable (2.31e-4)" "unprognostic (8.41e-2)" "unprognostic (2.46e-2)" "unprognostic (1.56e-2)" "unprognostic (8.04e-2)" "unprognostic (3.33e-1)" "unprognostic (5.90e-2)" "unprognostic (9.63e-2)" "unprognostic (1.49e-1)" "unprognostic (1.16e-1)" "unprognostic (1.65e-1)" "unprognostic (3.34e-2)" "unprognostic (2.83e-1)" "unprognostic (1.64e-1)" "unprognostic (1.55e-1)" "unprognostic (1.64e-1)" "unprognostic (1.76e-1)" BOLA1 CGI-143 ENSG00000178096 "BolA family member 1" Q9Y3E2 1 149887890-149900798 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007005 Approved NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 24: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 18 "HPA007005: " "unprognostic (3.91e-2)" "unprognostic (3.12e-2)" "unprognostic (3.99e-2)" "unprognostic (1.52e-1)" "unprognostic (1.75e-2)" "unprognostic (1.43e-2)" "unprognostic (9.62e-2)" "unprognostic (6.14e-2)" "unprognostic (7.96e-3)" "unprognostic (1.21e-1)" "potential prognostic favorable (2.52e-4)" "unprognostic (3.02e-2)" "unprognostic (3.13e-2)" "potential prognostic unfavorable (6.09e-4)" "unprognostic (2.00e-1)" "unprognostic (1.50e-2)" "unprognostic (2.49e-3)" "unprognostic (5.34e-3)" "unprognostic (2.14e-1)" "unprognostic (1.69e-1)" "unprognostic (2.52e-1)" "unprognostic (7.11e-3)" "unprognostic (4.81e-2)" "unprognostic (2.05e-1)" "unprognostic (4.25e-1)" "unprognostic (2.39e-3)" "unprognostic (6.01e-2)" "unprognostic (4.93e-2)" "unprognostic (1.34e-1)" "unprognostic (2.17e-1)" "unprognostic (1.80e-1)" BOLA2 "BOLA2A, My016" ENSG00000183336 "BolA family member 2" Q9H3K6 16 29453590-29454351 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA046696 Supported NA NA 480000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 54: Non-specific - Transcription" 4 "HPA046696: " "unprognostic (4.37e-3)" "unprognostic (1.34e-1)" "unprognostic (2.81e-1)" "unprognostic (1.53e-2)" "unprognostic (3.31e-2)" "unprognostic (1.10e-2)" "unprognostic (4.97e-2)" "unprognostic (2.76e-1)" "potential prognostic unfavorable (2.54e-8)" "unprognostic (3.65e-2)" "unprognostic (2.66e-3)" "unprognostic (2.27e-2)" "unprognostic (1.23e-1)" "unprognostic (7.31e-2)" "unprognostic (3.26e-3)" "unprognostic (2.09e-2)" "unprognostic (2.63e-1)" "unprognostic (9.88e-3)" "unprognostic (5.54e-2)" "unprognostic (7.14e-2)" "unprognostic (2.06e-1)" "unprognostic (1.43e-1)" "unprognostic (1.51e-1)" BOLA2-SMG1P6 ENSG00000261740 "BOLA2-SMG1P6 readthrough" 16 29443230-29454651 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Early spermatids: 5.7;Erythrocyte progenitors: 2.9;Megakaryocyte progenitors: 2.9;Megakaryocyte-Erythroid progenitors: 3.2;Megakaryocytes: 12.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 14: Neurons - Synaptic function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 17: Non-specific - RNA processing" "unprognostic (4.33e-2)" "potential prognostic unfavorable (1.60e-4)" "unprognostic (4.49e-3)" "unprognostic (7.36e-2)" "unprognostic (3.39e-3)" "unprognostic (1.62e-1)" "unprognostic (3.54e-3)" "unprognostic (5.93e-3)" "unprognostic (4.25e-2)" "unprognostic (1.89e-2)" "unprognostic (7.80e-2)" "unprognostic (8.84e-3)" "unprognostic (1.69e-3)" "unprognostic (1.18e-3)" "unprognostic (2.81e-1)" "unprognostic (5.79e-2)" "unprognostic (4.87e-1)" "unprognostic (2.56e-1)" "unprognostic (9.31e-2)" "unprognostic (1.05e-2)" "potential prognostic unfavorable (2.01e-4)" "unprognostic (2.09e-1)" "unprognostic (6.15e-2)" "unprognostic (9.89e-2)" "unprognostic (7.83e-2)" "unprognostic (1.57e-1)" "unprognostic (1.65e-1)" "unprognostic (1.73e-1)" "unprognostic (1.28e-1)" BOLA2B ENSG00000169627 "BolA family member 2B" Q9H3K6 16 30192932-30194306 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 4.3;Bergmann glia: 3.9;Brain excitatory neurons: 4.7;Brain inhibitory neurons: 4.5;Choroid plexus epithelial cells: 1.6;Ependymal cells: 2.5;Microglia: 4.3;Oligodendrocyte progenitor cells: 3.3;Oligodendrocytes: 11.5;Other brain neurons: 5.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA045380, HPA046696" Supported Uncertain Nucleoplasm NA NA 480000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 98: Neurons - Neurotransmission & signaling" 5 Nucleoplasm "HPA045380: , HPA046696: " "unprognostic (9.34e-3)" "unprognostic (4.35e-2)" "unprognostic (7.10e-3)" "unprognostic (2.52e-2)" "unprognostic (2.95e-1)" "unprognostic (8.13e-2)" "unprognostic (2.02e-2)" "unprognostic (2.10e-1)" "validated prognostic unfavorable (8.29e-8)" "validated prognostic unfavorable (3.51e-5)" "potential prognostic unfavorable (6.19e-8)" "unprognostic (1.82e-3)" "unprognostic (2.29e-3)" "unprognostic (7.80e-2)" "unprognostic (1.64e-2)" "unprognostic (3.24e-1)" "unprognostic (2.29e-2)" "unprognostic (2.70e-2)" "unprognostic (1.41e-1)" "unprognostic (6.93e-2)" "unprognostic (2.67e-1)" "unprognostic (3.83e-1)" "unprognostic (9.19e-2)" "unprognostic (7.32e-2)" "unprognostic (5.33e-2)" "unprognostic (5.64e-1)" "unprognostic (2.59e-1)" "unprognostic (8.27e-2)" BOLA3 ENSG00000163170 "BolA family member 3" Q53S33 2 74135400-74147912 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 162.0" "Cell type enhanced" "Detected in all" "Enteric transient amplifying cells: 189.5;Esophageal basal cells: 210.6;Extravillous trophoblasts: 221.5;Parietal cells: 475.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046393, HPA053162" Uncertain Supported "Nuclear bodies,Mitochondria,Cytosol" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 45: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 97: Non-specific - Cellular respiration" 11 "Nuclear bodies, Mitochondria" Cytosol "HPA046393: , HPA053162: " "unprognostic (2.93e-2)" "unprognostic (4.03e-2)" "unprognostic (1.12e-1)" "unprognostic (5.52e-2)" "unprognostic (8.27e-2)" "unprognostic (3.94e-2)" "unprognostic (1.83e-2)" "unprognostic (7.66e-3)" "unprognostic (6.58e-3)" "unprognostic (2.72e-3)" "potential prognostic unfavorable (9.14e-5)" "unprognostic (2.82e-3)" "unprognostic (4.88e-2)" "validated prognostic unfavorable (3.56e-4)" "validated prognostic unfavorable (5.94e-10)" "potential prognostic unfavorable (3.12e-4)" "unprognostic (4.27e-1)" "unprognostic (2.81e-2)" "unprognostic (6.29e-2)" "unprognostic (1.07e-2)" "unprognostic (1.55e-1)" "unprognostic (2.33e-2)" "unprognostic (2.24e-2)" "unprognostic (1.08e-1)" "unprognostic (3.37e-1)" "unprognostic (8.66e-2)" "unprognostic (1.63e-2)" "unprognostic (8.33e-2)" "unprognostic (3.89e-1)" "unprognostic (8.21e-2)" "unprognostic (1.82e-1)" BOLL BOULE ENSG00000152430 "Boule homolog, RNA binding protein" Q8N9W6 2 197726879-197786762 "Predicted intracellular proteins" "Differentiation, Spermatogenesis, Translation regulation" "Developmental protein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "testis: 45.7" "Group enriched" "Detected in some" 5 "Early primary spermatocytes: 217.2;Early spermatids: 137.4;Late primary spermatocytes: 508.0;Late spermatids: 184.6" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 10 "T-reg: 1.5" "Lineage enriched" "Detected in single" 10 "T-cells: 1.5" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA018678, HPA048813" Enhanced Approved "Mid piece,Principal piece,End piece,Annulus" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 56: Non-specific - Sensory perception" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 8 Annulus "Mid piece, Principal piece, End piece" "HPA018678: , HPA048813: " "unprognostic (3.79e-1)" BOP1 KIAA0124 ENSG00000261236 "BOP1 ribosomal biogenesis factor" Q14137 8 144262045-144291438 "Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 69.1" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 58.6;Esophageal basal cells: 71.9;Esophageal suprabasal cells: 51.9;Pancreatic acinar cells: 50.4;Undifferentiated spermatogonia: 58.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047869, HPA066764" Approved Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No 7100 "Cluster 25: Non-specific - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 39 "Nucleoli, Nucleoli rim" "Nucleoplasm, Mitotic chromosome" "HPA047869: , HPA066764: " "unprognostic (1.97e-2)" "unprognostic (1.35e-1)" "unprognostic (2.82e-1)" "potential prognostic unfavorable (1.98e-4)" "unprognostic (1.92e-1)" "unprognostic (4.00e-2)" "unprognostic (1.46e-1)" "unprognostic (1.16e-2)" "unprognostic (1.20e-2)" "potential prognostic unfavorable (4.96e-5)" "unprognostic (2.82e-2)" "unprognostic (8.17e-3)" "validated prognostic unfavorable (2.97e-5)" "validated prognostic unfavorable (1.06e-4)" "potential prognostic unfavorable (8.62e-4)" "unprognostic (4.65e-3)" "unprognostic (5.96e-2)" "unprognostic (4.13e-1)" "unprognostic (1.82e-2)" "unprognostic (3.14e-3)" "unprognostic (5.19e-2)" "unprognostic (4.22e-2)" "unprognostic (3.40e-2)" "unprognostic (1.97e-1)" "unprognostic (9.76e-2)" "unprognostic (3.23e-1)" "unprognostic (5.82e-2)" "unprognostic (6.10e-2)" BORA "C13orf34, FLJ22624" ENSG00000136122 "BORA aurora kinase A activator" Q6PGQ7 13 72727749-72756198 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 28.8;Epicardial cells: 36.4;Late primary spermatocytes: 35.1;Monocyte progenitors: 29.4;Sertoli cells: 30.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA040866 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA Yes "Cluster 5: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 19: Non-specific - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 17 "Nucleoplasm, Nucleoli fibrillar center" Cytosol "HPA040866: " "unprognostic (1.98e-1)" "unprognostic (1.48e-1)" "unprognostic (1.06e-1)" "unprognostic (2.96e-1)" "unprognostic (2.08e-1)" "unprognostic (3.15e-1)" "unprognostic (1.10e-1)" "unprognostic (6.52e-3)" "validated prognostic unfavorable (2.05e-5)" "validated prognostic unfavorable (1.80e-4)" "unprognostic (1.15e-1)" "potential prognostic unfavorable (2.56e-4)" "unprognostic (1.95e-3)" "unprognostic (1.21e-2)" "unprognostic (6.05e-2)" "unprognostic (8.36e-2)" "unprognostic (2.57e-1)" "unprognostic (7.50e-2)" "unprognostic (1.80e-2)" "unprognostic (9.71e-3)" "unprognostic (5.66e-3)" "unprognostic (2.10e-1)" "unprognostic (3.36e-1)" "unprognostic (1.26e-2)" "unprognostic (3.48e-3)" "unprognostic (1.89e-1)" "unprognostic (3.71e-1)" "unprognostic (3.23e-1)" BORCS5 "LOH12CR1, LOH1CR12" ENSG00000165714 "BLOC-1 related complex subunit 5" Q969J3 12 12357078-12471233 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 57.5;Bergmann glia: 51.0;Brain excitatory neurons: 59.6;Brain inhibitory neurons: 67.9;Choroid plexus epithelial cells: 74.7;Distal convoluted tubule cells: 55.6;Ependymal cells: 54.5;Loop of henle epithelial cells: 39.3;Microglia: 56.3;Oligodendrocyte progenitor cells: 38.2;Oligodendrocytes: 144.1;Other brain neurons: 71.3;Papillary tip epithelial cells: 34.1;Podocytes: 73.0;Proximal tubule cells: 33.8;Renal collecting duct intercalated cells: 40.0;Renal collecting duct principal cells: 43.2;Renal connecting tubule cells: 40.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039509, HPA043627" Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 102: Non-specific - Mixed function" 16 "Vesicles, Plasma membrane" "HPA039509: , HPA043627: " "unprognostic (2.06e-1)" "unprognostic (1.56e-1)" "unprognostic (2.05e-1)" "unprognostic (3.15e-2)" "unprognostic (8.18e-2)" "unprognostic (2.12e-1)" "unprognostic (2.11e-2)" "unprognostic (5.25e-2)" "unprognostic (3.35e-1)" "unprognostic (1.63e-3)" "unprognostic (2.21e-1)" "unprognostic (2.21e-1)" "unprognostic (7.31e-3)" "unprognostic (3.12e-3)" "unprognostic (8.98e-2)" "unprognostic (6.35e-2)" "unprognostic (1.20e-1)" "unprognostic (1.62e-1)" "unprognostic (2.18e-1)" "unprognostic (4.96e-2)" "unprognostic (1.70e-2)" "unprognostic (1.43e-1)" "unprognostic (2.06e-1)" "unprognostic (1.88e-2)" "unprognostic (9.50e-2)" "unprognostic (2.15e-1)" "unprognostic (2.84e-1)" "unprognostic (1.05e-2)" "unprognostic (2.23e-1)" BORCS6 "C17orf59, FLJ20014" ENSG00000196544 "BLOC-1 related complex subunit 6" Q96GS4 17 8188345-8190180 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 42.7;Platelets: 109.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045415, HPA060791" Uncertain Approved "Golgi apparatus,Vesicles" NA NA 5500 "Cluster 45: Eosinophils - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 18: Non-specific - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 47: Platelets - Hemostasis" 99 "Golgi apparatus, Vesicles" "HPA045415: , HPA060791: " "unprognostic (4.07e-1)" "unprognostic (3.75e-1)" "unprognostic (1.39e-1)" "unprognostic (3.46e-2)" "unprognostic (1.98e-1)" "unprognostic (1.88e-1)" "unprognostic (1.74e-2)" "unprognostic (6.28e-2)" "unprognostic (2.59e-1)" "unprognostic (1.85e-3)" "unprognostic (4.22e-3)" "potential prognostic favorable (1.66e-4)" "unprognostic (1.23e-2)" "unprognostic (4.09e-2)" "unprognostic (2.31e-1)" "unprognostic (1.43e-1)" "unprognostic (2.38e-1)" "unprognostic (1.12e-1)" "unprognostic (2.22e-1)" "potential prognostic favorable (7.54e-4)" "unprognostic (9.04e-2)" "unprognostic (2.50e-1)" "unprognostic (1.87e-1)" "unprognostic (3.44e-2)" "unprognostic (2.72e-2)" "unprognostic (8.07e-2)" "unprognostic (3.68e-2)" "unprognostic (2.78e-1)" "unprognostic (1.02e-1)" BORCS7 "C10orf32, FLJ40752" ENSG00000166275 "BLOC-1 related complex subunit 7" Q96B45 10 102854259-102864961 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 22.6;Bergmann glia: 26.5;Brain excitatory neurons: 26.6;Brain inhibitory neurons: 29.0;Choroid plexus epithelial cells: 21.1;Ependymal cells: 33.9;Late primary spermatocytes: 16.7;Microglia: 17.5;Oligodendrocyte progenitor cells: 19.1;Oligodendrocytes: 31.0;Other brain neurons: 29.5;Parietal cells: 19.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Endothelial cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037648, HPA077528" Approved Approved Vesicles,Cytosol NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 52: Non-specific - Mitochondria" "Cluster 98: Neurons - Neurotransmission & signaling" 16 "Vesicles, Cytosol" "HPA037648: , HPA077528: " "unprognostic (5.26e-2)" "unprognostic (1.10e-1)" "unprognostic (5.43e-2)" "unprognostic (2.76e-2)" "unprognostic (4.18e-3)" "unprognostic (8.93e-2)" "unprognostic (1.13e-1)" "unprognostic (9.76e-2)" "unprognostic (9.68e-2)" "validated prognostic favorable (3.18e-10)" "validated prognostic favorable (5.21e-5)" "unprognostic (1.73e-2)" "potential prognostic favorable (1.58e-4)" "unprognostic (8.42e-2)" "unprognostic (8.59e-2)" "unprognostic (2.81e-1)" "unprognostic (1.71e-1)" "unprognostic (1.35e-3)" "potential prognostic unfavorable (7.24e-4)" "unprognostic (1.81e-1)" "unprognostic (8.68e-2)" "unprognostic (1.44e-2)" "unprognostic (3.13e-2)" "unprognostic (3.82e-1)" "unprognostic (3.52e-2)" "unprognostic (2.31e-2)" "unprognostic (4.19e-2)" "unprognostic (9.13e-2)" "unprognostic (2.10e-3)" BORCS8 MEF2BNB ENSG00000254901 "BLOC-1 related complex subunit 8" Q96FH0 19 19176903-19192591 "Predicted intracellular proteins" "Disease variant, Intellectual disability, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 2.7;Cardiomyocytes: 1.9;Epicardial cells: 4.5;Fallopian tube ciliated cells: 1.9;Megakaryocytes: 6.2" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045700 Approved Approved Vesicles NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 23: Non-specific - Transcription" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 19 Vesicles "HPA045700: " "unprognostic (5.63e-2)" "unprognostic (1.41e-2)" "unprognostic (1.21e-1)" "unprognostic (5.42e-2)" "unprognostic (2.68e-1)" "unprognostic (2.56e-2)" "unprognostic (1.34e-1)" "unprognostic (7.59e-3)" "unprognostic (7.78e-2)" "potential prognostic favorable (6.73e-6)" "unprognostic (2.81e-2)" "unprognostic (1.75e-3)" "unprognostic (2.16e-3)" "unprognostic (1.47e-2)" "unprognostic (2.20e-1)" "unprognostic (1.45e-1)" "unprognostic (8.41e-2)" "unprognostic (6.06e-2)" "unprognostic (3.14e-1)" "potential prognostic favorable (8.65e-5)" "unprognostic (1.23e-1)" "unprognostic (4.78e-2)" "unprognostic (1.30e-1)" "potential prognostic favorable (9.06e-4)" "unprognostic (1.50e-2)" "unprognostic (2.16e-1)" "unprognostic (6.84e-2)" "unprognostic (4.93e-3)" "unprognostic (7.10e-2)" BORCS8-MEF2B MEF2BNB-MEF2B ENSG00000064489 "BORCS8-MEF2B readthrough" 19 19145569-19192158 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 14 "Distal convoluted tubule cells: 8.9;Loop of henle epithelial cells: 7.5;Papillary tip epithelial cells: 3.5;Podocytes: 8.0;Proximal tubule cells: 7.7;Renal collecting duct intercalated cells: 4.7;Renal collecting duct principal cells: 4.7;Renal connecting tubule cells: 7.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" HPA004734 Uncertain Approved "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 25: Non-specific - Ribosome" "Cluster 105: Non-specific - Mixed function" "Nucleoplasm, Cytosol" "Cell Junctions" "HPA004734: " "unprognostic (2.99e-1)" "unprognostic (2.01e-1)" BPGM ENSG00000172331 "Bisphosphoglycerate mutase" P07738 7 134646811-134679816 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis "Hydrolase, Isomerase" "Congenital erythrocytosis, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 82.2" "Group enriched" "Detected in many" 7 "Erythrocytes: 313.0;Oocytes: 483.5;Syncytiotrophoblasts: 559.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Erythrocytes, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016493, HPA028735" Enhanced Approved "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA 28000000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." 7 "Nucleoli, Nucleoli rim" Nucleoplasm "HPA016493: , HPA028735: " "unprognostic (1.32e-2)" "unprognostic (1.10e-1)" "unprognostic (2.39e-1)" "unprognostic (1.76e-1)" "unprognostic (1.17e-1)" "unprognostic (3.25e-2)" "unprognostic (1.99e-1)" "unprognostic (1.55e-1)" "unprognostic (4.53e-2)" "unprognostic (5.32e-2)" "potential prognostic favorable (4.32e-9)" "unprognostic (3.88e-2)" "unprognostic (7.55e-2)" "unprognostic (1.05e-3)" "unprognostic (1.69e-1)" "unprognostic (4.39e-2)" "unprognostic (1.57e-1)" "unprognostic (3.78e-1)" "unprognostic (2.16e-1)" "unprognostic (2.79e-1)" "unprognostic (4.22e-3)" "unprognostic (3.36e-2)" "unprognostic (2.00e-2)" "unprognostic (7.41e-2)" "unprognostic (1.74e-1)" "unprognostic (8.28e-2)" "unprognostic (1.28e-1)" "unprognostic (1.49e-1)" "unprognostic (3.32e-1)" "unprognostic (4.04e-1)" "unprognostic (1.30e-1)" BPHL "Bph-rp, MCNAA, VACVase" ENSG00000137274 "Biphenyl hydrolase like" Q86WA6 6 3118374-3153578 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 102.8;liver: 79.0" "Cell type enhanced" "Detected in many" "Adipocytes: 88.4;Enterocytes: 94.5;Hepatocytes: 96.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036752, HPA036753" Enhanced Approved Mitochondria NA NA 7000 "Cluster 18: Non-specific - Translation" "Cluster 76: Non-specific - Metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 89: Adipocytes - Lipid metabolism" Mitochondria "HPA036752: , HPA036753: " "unprognostic (1.37e-1)" "unprognostic (2.25e-2)" "unprognostic (4.82e-2)" "unprognostic (1.49e-1)" "unprognostic (1.19e-1)" "unprognostic (3.63e-2)" "unprognostic (2.54e-1)" "unprognostic (9.89e-3)" "unprognostic (1.33e-3)" "unprognostic (3.59e-1)" "validated prognostic favorable (5.10e-9)" "validated prognostic favorable (5.14e-4)" "potential prognostic favorable (2.43e-5)" "unprognostic (1.03e-1)" "unprognostic (3.92e-3)" "unprognostic (2.71e-1)" "unprognostic (2.42e-1)" "unprognostic (1.25e-1)" "unprognostic (1.02e-1)" "unprognostic (6.47e-3)" "unprognostic (1.35e-1)" "unprognostic (2.41e-1)" "unprognostic (1.34e-1)" "unprognostic (4.04e-2)" "unprognostic (8.57e-2)" "unprognostic (8.20e-2)" "unprognostic (3.87e-1)" "unprognostic (2.62e-2)" "unprognostic (5.22e-3)" "unprognostic (1.14e-2)" "unprognostic (1.85e-1)" BPI BPIFD1 ENSG00000101425 "Bactericidal permeability increasing protein" P17213 20 38304150-38337505 "Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Immunity, Innate immunity" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 87 "bone marrow: 1420.3" "Group enriched" "Detected in some" 4 "Early spermatids: 250.8;Late spermatids: 293.8;Neutrophil progenitors: 848.7" "Group enriched" "Detected in some" 9 "fibroblast: 3.8;pericyte: 1.5" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "classical monocyte: 14.5;neutrophil: 7.1" "Group enriched" "Detected in many" 17 "granulocytes: 7.1;monocytes: 14.5" "Cancer enriched" "Detected in some" 4 "Leukemia: 20.4" "Liver - Erythroid cells, Lung - Neutrophils_1, Prostate - Fibroblasts, Spleen - Neutrophils_1, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA061284 Enhanced "Secreted to blood" Immunity NA NA 7290000 45000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 15: Bone marrow - Innate immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 3 "HPA061284: " "potential prognostic favorable (7.63e-4)" "unprognostic (2.66e-2)" "unprognostic (6.75e-2)" BPIFA1 "bA49G10.5, LUNX, PLUNC, SPLUNC1" ENSG00000198183 "BPI fold containing family A member 1" Q9NP55 20 33235995-33243311 "Plasma proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 5.8;lung: 18.6;pituitary gland: 12.3" "Cell type enriched" "Detected in some" 14 "Conjunctival goblet cells: 23186.2" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 14 "Lung Adenocarcinoma (TCGA): 747.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 28 "pancreatic cancer: 28.5" "Lung - Respiratory ciliated cells, Testis - Late spermatids" "Region enriched" "Detected in single" 10 "cerebellum: 2.0" "Not detected" "Not detected" CAB025669 Supported "Secreted in other tissues" Immunity NA NA 650000 "Cluster 13: Lung - Secretion" "Cluster 7: Liver cancer - Metabolism" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 48 "CAB025669: " "unprognostic (1.27e-3)" "unprognostic (2.14e-1)" "unprognostic (2.11e-1)" "unprognostic (1.64e-1)" "unprognostic (3.39e-1)" "unprognostic (1.15e-1)" "unprognostic (3.43e-1)" "unprognostic (6.83e-2)" "unprognostic (3.85e-2)" "unprognostic (1.47e-1)" BPIFA2 "bA49G10.1, C20orf70, PSP, SPLUNC2" ENSG00000131050 "BPI fold containing family A member 2" Q96DR5 20 33161768-33181412 "Predicted secreted proteins" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 1613 "salivary gland: 6453.2" "Cell type enriched" "Detected in some" 4 "Salivary acinar cells: 3985.0" "Cell type enhanced" "Detected in single" "hippocampal CA4: 1.5" "Group enriched" "Detected in some" 5 "Kidney Chromophobe (TCGA): 5.3;Lung Adenocarcinoma (TCGA): 8.1;Pancreatic Adenocarcinoma (TCGA): 5.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 2.6;lung cancer: 2.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA044006 Enhanced "Secreted to digestive system" Defense NA NA "Cluster 82: Salivary gland - Secretion" "Cluster 7: Liver cancer - Metabolism" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 4 "HPA044006: " "unprognostic (1.68e-1)" "unprognostic (8.48e-2)" "unprognostic (1.87e-1)" "unprognostic (3.56e-2)" "unprognostic (2.56e-2)" BPIFA3 "bA49G10.4, C20orf71, SPLUNC3" ENSG00000131059 "BPI fold containing family A member 3" Q9BQP9 20 33217310-33227806 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 525 "testis: 52.4" "Cell type enriched" "Detected in some" 6 "Late spermatids: 5535.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA062708 Enhanced "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 1 "HPA062708: " BPIFB1 "bA49G10.6, C20orf114, dJ1187J4.1, LPLUNC1, MGC14597, VEMSGP" ENSG00000125999 "BPI fold containing family B member 1" Q8TDL5 20 33273480-33309871 "Plasma proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "cervix: 532.0;salivary gland: 255.4;stomach 1: 483.0" "Group enriched" "Detected in some" 8 "Conjunctival goblet cells: 13860.0;Respiratory deuterosomal cells: 7937.4;Respiratory secretory cells: 9172.4;Submucosal glandular cells: 5146.7" "Cell type enhanced" "Detected in some" "hippocampal dentate gyrus: 1.2;medium spiny neuron: 1.1" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 179.4;Stomach Adenocarcinoma (TCGA): 201.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 7 "breast cancer: 122.7" "Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in single" 6 "olfactory bulb: 4.8" "Low region specificity" "Detected in many" HPA024256 Enhanced "Secreted in other tissues" Immunity NA NA 5200000 "Cluster 60: Stomach - Digestion" "Cluster 51: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 9 "HPA024256: " "unprognostic (1.30e-1)" "unprognostic (1.64e-1)" "unprognostic (4.31e-2)" "unprognostic (1.49e-1)" "unprognostic (6.42e-3)" "unprognostic (3.01e-1)" "unprognostic (2.51e-1)" "unprognostic (1.37e-1)" "unprognostic (7.27e-2)" "unprognostic (2.06e-2)" "unprognostic (6.71e-2)" "unprognostic (1.96e-2)" "unprognostic (7.58e-2)" "unprognostic (1.83e-1)" "unprognostic (2.77e-1)" "unprognostic (1.45e-1)" "unprognostic (1.98e-2)" BPIFB2 "BPIL1, C20orf184, dJ726C3.2, LPLUNC2" ENSG00000078898 "BPI fold containing family B member 2" Q8N4F0 20 33007704-33023703 "Plasma proteins, Predicted secreted proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 26 "salivary gland: 2419.0" "Cell type enriched" "Detected in some" 7 "Submucosal glandular cells: 685.8" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 36.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "breast cancer: 13.5;liver cancer: 14.6" "Minor Salivary Gland - Minor salivary glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049491, HPA060121" Enhanced Approved Vesicles "Secreted in other tissues" "No annotated function" NA NA 51000 "Cluster 82: Salivary gland - Secretion" "Cluster 27: Breast cancer - Unknown function" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 2 Vesicles "HPA049491: , HPA060121: " "unprognostic (2.20e-1)" "unprognostic (4.97e-1)" "unprognostic (3.74e-2)" "unprognostic (1.19e-1)" "unprognostic (2.25e-3)" "unprognostic (1.15e-1)" "unprognostic (2.74e-1)" "unprognostic (2.10e-1)" "unprognostic (2.14e-2)" "unprognostic (3.03e-1)" "unprognostic (4.71e-2)" "unprognostic (3.46e-3)" BPIFB3 "C20orf185, dJ726C3.4, LPLUNC3, RYA3" ENSG00000186190 "BPI fold containing family B member 3" P59826 20 33053903-33073847 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Early spermatids: 2.9;Late spermatids: 8.8;Megakaryocyte progenitors: 1.6;Megakaryocytes: 6.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Ovary Serous Cystadenocarcinoma (TCGA): 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045741 Uncertain "Secreted in other tissues" "No annotated function" NA NA "Cluster 5: Rhabdoid - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 2 "HPA045741: " "unprognostic (9.20e-2)" BPIFB4 "C20orf186, dJ726C3.5, LPLUNC4" ENSG00000186191 "BPI fold containing family B member 4" P59827 20 33079643-33111751 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 13 "pituitary gland: 7.5" "Cell type enhanced" "Detected in some" "Epicardial cells: 2.3;Foveolar cells: 1.5;Gastric chief cells: 2.2;Mucous neck cells: 5.1;Oocytes: 9.2;Pituitary stem cells: 5.2;Platelets: 4.2;Undifferentiated spermatogonia: 2.4" "Cell type enhanced" "Detected in single" "choroid plexus epithelial cell: 1.0" "Not detected" "Not detected" "Region enhanced" "Detected in single" "choroid plexus: 1.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Kidney cancer: 2.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA047388 Approved "Actin filaments,Cytosol" "Secreted - unknown location" "No annotated function" NA NA "Cluster 20: Pituitary gland - Hormone signaling" "Cluster 36: Choroid plexus - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 68: Foveolar cells - Mucosal defense" "Actin filaments, Cytosol" "HPA047388: " "unprognostic (6.47e-2)" BPIFB6 "BPIL3, LPLUNC6" ENSG00000167104 "BPI fold containing family B member 6" Q8NFQ5 20 33031648-33044047 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 32 "salivary gland: 3.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Minor Salivary Gland - Minor salivary glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA043057 Uncertain "Secreted in other tissues" "No annotated function" NA NA "Cluster 82: Salivary gland - Secretion" "Cluster 27: Breast cancer - Unknown function" "Cluster 38: Secretory epithelial cells - Exocrine secretion" "HPA043057: " BPIFC "BPIL2, dJ149A16.7" ENSG00000184459 "BPI fold containing family C" Q8NFQ6 22 32413845-32464484 "Predicted secreted proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "skin 1: 42.9" "Group enriched" "Detected in some" 4 "Early spermatids: 24.0;Late primary spermatocytes: 17.7;Late spermatids: 12.7;Suprabasal keratinocytes: 10.4" "Low cell type specificity" "Detected in some" "Group enriched" "Detected in some" 10 "Head and Neck Squamous Cell Carcinoma (TCGA): 3.7;Skin Cutaneous Melanoma (TCGA): 4.2" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 16 "basophil: 1.5" "Lineage enriched" "Detected in single" 16 "granulocytes: 1.5" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Secreted in other tissues" Immunity NA NA "Cluster 37: Skin - Keratinization" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" "unprognostic (1.89e-1)" "unprognostic (1.08e-1)" BPNT1 ENSG00000162813 "3'(2'), 5'-bisphosphate nucleotidase 1" O95861 1 220057482-220090462 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 51.2;Enterocytes: 61.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048461 Approved Approved "Nuclear speckles" NA NA 300000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 77: Intestine - Digestion" "Cluster 30: White matter - Myelination" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 8 "Nuclear speckles" "HPA048461: " "unprognostic (9.37e-3)" "unprognostic (1.74e-2)" "unprognostic (8.32e-2)" "potential prognostic unfavorable (8.51e-4)" "unprognostic (1.04e-2)" "unprognostic (5.02e-3)" "unprognostic (3.71e-2)" "unprognostic (1.92e-1)" "unprognostic (1.12e-1)" "unprognostic (2.60e-2)" "potential prognostic favorable (1.33e-8)" "unprognostic (3.50e-2)" "unprognostic (4.31e-2)" "unprognostic (8.11e-3)" "unprognostic (2.32e-1)" "unprognostic (1.45e-1)" "unprognostic (7.98e-2)" "unprognostic (5.82e-3)" "unprognostic (3.17e-2)" "unprognostic (8.92e-2)" "unprognostic (1.97e-3)" "unprognostic (3.63e-2)" "unprognostic (1.56e-1)" "unprognostic (1.77e-1)" "unprognostic (8.55e-2)" "unprognostic (7.53e-2)" "unprognostic (1.15e-1)" "unprognostic (1.48e-1)" "unprognostic (1.57e-1)" "unprognostic (2.97e-2)" "unprognostic (3.10e-2)" BPNT2 "FLJ20421, gPAPP, IMPA3, IMPAD1" ENSG00000104331 "3'(2'), 5'-bisphosphate nucleotidase 2" Q9NX62 8 56957931-56993867 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009411 Supported Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 450000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 17: Non-specific - RNA processing" 3 "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA009411: " "unprognostic (8.69e-3)" "potential prognostic unfavorable (4.19e-4)" "unprognostic (2.93e-2)" "unprognostic (1.57e-1)" "unprognostic (2.15e-1)" "unprognostic (1.40e-1)" "unprognostic (4.74e-2)" "unprognostic (1.79e-1)" "potential prognostic unfavorable (8.63e-4)" "unprognostic (8.61e-3)" "unprognostic (6.41e-2)" "unprognostic (8.25e-2)" "unprognostic (1.08e-1)" "unprognostic (1.44e-3)" "unprognostic (1.40e-3)" "unprognostic (1.24e-1)" "unprognostic (1.25e-1)" "unprognostic (6.65e-2)" "unprognostic (8.01e-3)" "unprognostic (8.65e-3)" "unprognostic (2.03e-1)" "unprognostic (1.51e-1)" "unprognostic (3.72e-1)" "unprognostic (3.07e-1)" "unprognostic (2.85e-1)" "unprognostic (4.52e-3)" "unprognostic (1.76e-1)" "unprognostic (1.02e-1)" "unprognostic (1.07e-1)" BPTF "FAC1, FALZ, NURF301" ENSG00000171634 "Bromodomain PHD finger transcription factor" Q12830 17 67825503-67984378 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029069, HPA048289" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 64: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 7: Non-specific - Transcription" 31 Nucleoplasm Cytosol "HPA029069: , HPA048289: " "unprognostic (1.54e-1)" "unprognostic (9.24e-2)" "potential prognostic favorable (1.74e-4)" "unprognostic (4.45e-3)" "unprognostic (1.59e-1)" "unprognostic (1.48e-1)" "unprognostic (4.04e-2)" "unprognostic (1.32e-2)" "unprognostic (3.83e-1)" "unprognostic (1.42e-2)" "unprognostic (3.15e-3)" "unprognostic (6.40e-3)" "unprognostic (2.58e-1)" "unprognostic (2.96e-3)" "unprognostic (2.91e-1)" "unprognostic (1.07e-2)" "unprognostic (1.44e-3)" "unprognostic (8.16e-2)" "unprognostic (1.68e-2)" "unprognostic (3.40e-1)" "unprognostic (4.51e-2)" "unprognostic (5.80e-3)" "unprognostic (1.86e-2)" "unprognostic (2.41e-2)" "unprognostic (1.33e-2)" "unprognostic (3.94e-3)" "unprognostic (3.15e-1)" "unprognostic (3.78e-1)" "unprognostic (2.79e-1)" "unprognostic (1.02e-1)" "unprognostic (6.06e-2)" BPY2 "BPY2A, VCY2, VCY2A" ENSG00000183753 "Basic charge Y-linked 2" O14599 Y 22973819-23005465 "Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "testis: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 57: Testis - Spermatogenesis" 4 BPY2B VCY2B ENSG00000183795 "Basic charge Y-linked 2B" O14599 Y 24607560-24639207 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "testis: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 57: Testis - Spermatogenesis" 1 BPY2C VCY2C ENSG00000185894 "Basic charge Y-linked 2C" O14599 Y 25030901-25062548 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "testis: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 57: Testis - Spermatogenesis" 1 BRAF "BRAF-1, BRAF1" ENSG00000157764 "B-Raf proto-oncogene, serine/threonine kinase" P15056 7 140719327-140924929 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Transporters" "Allosteric enzyme, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Cardiomyopathy, Deafness, Disease variant, Ectodermal dysplasia, FDA approved drug targets, Intellectual disability, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 2034.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pancreas - Endothelial cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001328, CAB004552, HPA071048, CAB080447, CAB080451, CAB080452, CAB080531" Supported Supported "Vesicles,Plasma membrane,Primary cilium,Centriolar satellite,Basal body,Cytosol,Mid piece,Principal piece,End piece" No No "Cluster 20: Non-specific - DNA binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 39: Non-specific - Transcription" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 174 "Vesicles, Cytosol" "Plasma membrane, Primary cilium, Centriolar satellite, Basal body, Mid piece, Principal piece, End piece" "CAB004552: , CAB080447: , CAB080451: , CAB080452: , CAB080531: , HPA001328: , HPA071048: " "potential prognostic favorable (4.52e-4)" "unprognostic (8.04e-3)" "unprognostic (2.25e-1)" "unprognostic (1.00e-1)" "unprognostic (6.81e-2)" "unprognostic (1.39e-1)" "unprognostic (1.64e-1)" "unprognostic (1.79e-2)" "unprognostic (2.07e-2)" "unprognostic (4.01e-2)" "validated prognostic favorable (1.04e-4)" "validated prognostic favorable (2.24e-4)" "unprognostic (1.26e-1)" "unprognostic (3.93e-2)" "unprognostic (1.48e-1)" "unprognostic (7.31e-2)" "unprognostic (7.33e-3)" "unprognostic (1.95e-1)" "unprognostic (1.82e-1)" "unprognostic (7.86e-2)" "potential prognostic unfavorable (1.29e-4)" "unprognostic (2.08e-1)" "unprognostic (2.47e-2)" "unprognostic (1.21e-1)" "unprognostic (8.43e-2)" "unprognostic (2.20e-3)" "unprognostic (5.50e-2)" "unprognostic (2.47e-1)" "unprognostic (1.41e-1)" "unprognostic (1.77e-2)" "unprognostic (6.27e-2)" BRAP "BRAP2, IMP, RNF52" ENSG00000089234 "BRCA1 associated protein" Q7Z569 12 111642146-111685956 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 63.5" "Cell type enhanced" "Detected in many" "Early spermatids: 278.6;Late primary spermatocytes: 390.6;Late spermatids: 600.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040357, HPA058820" Approved Supported "Nuclear membrane,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 39: Testis - Nuclear processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 23 Cytosol "Nuclear membrane" "HPA040357: , HPA058820: " "unprognostic (5.63e-2)" "unprognostic (7.17e-2)" "unprognostic (5.13e-1)" "unprognostic (4.18e-2)" "unprognostic (1.51e-1)" "unprognostic (3.47e-2)" "unprognostic (2.03e-1)" "unprognostic (6.43e-2)" "unprognostic (8.91e-2)" "unprognostic (1.16e-2)" "validated prognostic favorable (9.17e-6)" "validated prognostic favorable (6.55e-4)" "unprognostic (2.03e-1)" "potential prognostic unfavorable (2.10e-7)" "unprognostic (7.10e-3)" "unprognostic (4.23e-2)" "unprognostic (2.22e-1)" "unprognostic (1.41e-1)" "unprognostic (4.64e-2)" "unprognostic (5.08e-2)" "unprognostic (7.82e-3)" "unprognostic (2.74e-1)" "unprognostic (5.03e-2)" "unprognostic (9.29e-2)" "unprognostic (1.63e-1)" "unprognostic (1.13e-2)" "unprognostic (3.16e-2)" "unprognostic (1.55e-1)" "unprognostic (2.45e-1)" "unprognostic (5.11e-2)" "unprognostic (7.31e-2)" BRAT1 "BAAT1, C7orf27, MGC22916" ENSG00000106009 "BRCA1 associated ATM activator 1" Q6PJG6 7 2537810-2555694 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029455, HPA076508" Approved Supported Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 70: Non-specific - Protein processing" "Cluster 27: Non-specific - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 65: Non-specific - Cell growth & division" 33 Nucleoplasm "HPA029455: , HPA076508: " "unprognostic (3.67e-2)" "unprognostic (1.58e-2)" "unprognostic (4.46e-2)" "unprognostic (1.43e-1)" "unprognostic (2.79e-1)" "unprognostic (1.08e-2)" "unprognostic (1.81e-1)" "unprognostic (1.20e-1)" "unprognostic (1.02e-2)" "unprognostic (5.98e-2)" "unprognostic (8.93e-2)" "unprognostic (9.40e-2)" "potential prognostic unfavorable (1.16e-4)" "unprognostic (1.27e-2)" "unprognostic (3.15e-2)" "unprognostic (9.96e-2)" "unprognostic (5.11e-2)" "unprognostic (2.92e-1)" "unprognostic (2.02e-1)" "unprognostic (1.26e-1)" "unprognostic (1.09e-3)" "unprognostic (1.91e-1)" "unprognostic (3.57e-1)" "unprognostic (4.29e-1)" "unprognostic (7.78e-3)" "unprognostic (1.47e-1)" "unprognostic (1.95e-2)" "unprognostic (5.88e-2)" "unprognostic (1.23e-1)" "unprognostic (6.16e-2)" BRCA1 "BRCC1, FANCS, PPP1R53, RNF53" ENSG00000012048 "BRCA1 DNA repair associated" P38398 17 43044295-43170245 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA recombination, DNA repair, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, DNA-binding, Transferase" "Cancer-related genes, Disease variant, Fanconi anemia, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 211.2;Erythrocyte progenitors: 157.1;Megakaryocyte progenitors: 147.3;Monocyte progenitors: 129.9;Neutrophil progenitors: 96.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 6.2;classical monocyte: 14.6;intermediate monocyte: 4.5;myeloid DC: 10.9;neutrophil: 10.9" "Group enriched" "Detected in all" 6 "dendritic cells: 10.9;granulocytes: 10.9;monocytes: 14.6" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB001946, HPA004840, HPA034966, HPA057371, CAB080453, CAB080454" Supported Supported "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 11: White matter - Signal transduction" "Cluster 27: Breast cancer - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 389 "Nuclear bodies" Nucleoplasm "CAB001946: , CAB080453: , CAB080454: , HPA004840: , HPA034966: , HPA057371: " "unprognostic (2.23e-1)" "unprognostic (3.89e-3)" "unprognostic (1.03e-1)" "unprognostic (3.41e-2)" "unprognostic (2.07e-1)" "unprognostic (1.19e-2)" "unprognostic (2.43e-1)" "unprognostic (4.62e-2)" "unprognostic (2.87e-2)" "unprognostic (1.62e-3)" "unprognostic (8.62e-2)" "unprognostic (5.91e-2)" "unprognostic (1.51e-2)" "validated prognostic unfavorable (7.06e-4)" "validated prognostic unfavorable (3.09e-5)" "validated prognostic unfavorable (4.90e-4)" "validated prognostic unfavorable (1.42e-4)" "unprognostic (1.11e-1)" "unprognostic (2.33e-2)" "unprognostic (6.23e-2)" "unprognostic (3.21e-1)" "unprognostic (4.69e-2)" "unprognostic (1.19e-2)" "unprognostic (9.07e-2)" "potential prognostic favorable (7.38e-5)" "unprognostic (1.02e-3)" "unprognostic (1.81e-3)" "unprognostic (2.93e-2)" "unprognostic (3.10e-1)" "unprognostic (3.62e-1)" "unprognostic (3.18e-2)" BRCA2 "BRCC2, FACD, FAD, FAD1, FANCD, FANCD1, XRCC11" ENSG00000139618 "BRCA2 DNA repair associated" P51587 13 32315086-32400268 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes, Disease variant, Fanconi anemia, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.2;lymphoid tissue: 4.2;testis: 2.9" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 107.6;Early primary spermatocytes: 183.5;Erythrocyte progenitors: 150.6;Megakaryocyte progenitors: 120.3;Monocyte progenitors: 186.9;Neutrophil progenitors: 106.8;pDCs: 94.2;Plasma cells: 68.6;Respiratory deuterosomal cells: 58.1;Undifferentiated spermatogonia: 59.1" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 19.2;choroid plexus epithelial cell: 9.4" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Macrophages, Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA026815 Uncertain Supported Nucleoplasm,Cytosol Yes No "Cluster 13: Non-specific - Mitochondria" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 19: Non-specific - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 83 Nucleoplasm Cytosol "HPA026815: " "unprognostic (1.80e-1)" "unprognostic (3.38e-1)" "unprognostic (2.26e-1)" "unprognostic (1.17e-1)" "unprognostic (3.07e-2)" "unprognostic (8.91e-2)" "unprognostic (1.16e-2)" "unprognostic (9.86e-3)" "unprognostic (3.43e-1)" "potential prognostic unfavorable (3.60e-6)" "unprognostic (1.88e-2)" "unprognostic (2.73e-3)" "unprognostic (2.73e-2)" BRCC3 "BRCC36, C6.1A, CXorf53" ENSG00000185515 "BRCA1/BRCA2-containing complex subunit 3" P46736 X 155071420-155123077 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Mitosis, Ubl conjugation pathway" "Chromatin regulator, Hydrolase, Metalloprotease, Protease" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Stomach - Mitotic cells (Stomach), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048737 Supported Nucleoplasm NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 17: Intestine - Digestion" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 36: Non-specific - mRNA processing" "Cluster 7: Non-specific - Transcription" 28 Nucleoplasm "HPA048737: " "unprognostic (2.46e-2)" "potential prognostic unfavorable (6.91e-4)" "unprognostic (1.41e-1)" "unprognostic (1.04e-1)" "unprognostic (7.64e-2)" "unprognostic (2.01e-1)" "unprognostic (2.41e-1)" "unprognostic (1.39e-1)" "unprognostic (3.80e-2)" "unprognostic (7.87e-3)" "unprognostic (2.69e-2)" "unprognostic (2.83e-2)" "unprognostic (1.34e-1)" "unprognostic (1.13e-2)" "unprognostic (4.02e-3)" "unprognostic (4.86e-2)" "unprognostic (2.92e-3)" "unprognostic (9.01e-2)" "unprognostic (6.16e-2)" "unprognostic (1.35e-1)" "unprognostic (1.40e-2)" "unprognostic (7.49e-3)" "unprognostic (1.42e-1)" "unprognostic (1.24e-1)" "potential prognostic favorable (1.34e-4)" "unprognostic (2.01e-1)" "unprognostic (3.70e-2)" "unprognostic (6.80e-2)" "unprognostic (7.00e-2)" "unprognostic (2.65e-1)" "unprognostic (4.92e-2)" BRD1 "BRL, BRPF2" ENSG00000100425 "Bromodomain containing 1" O95696 22 49773283-49827873 "Predicted intracellular proteins" "Erythrocyte maturation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Innate lymphoid cells: 204.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Pancreas - Endothelial cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000807, HPA001063" Enhanced Supported "Nuclear speckles" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 39: Testis - Nuclear processes" "Cluster 15: Non-specific - Transcription" "Cluster 66: Non-specific - Mitochondria" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 34 "Nuclear speckles" "HPA000807: , HPA001063: " "unprognostic (1.10e-1)" "unprognostic (9.09e-2)" "potential prognostic favorable (6.58e-4)" "unprognostic (2.79e-1)" "unprognostic (1.29e-2)" "unprognostic (1.25e-1)" "unprognostic (1.79e-1)" "potential prognostic favorable (6.65e-4)" "unprognostic (3.50e-2)" "unprognostic (2.25e-2)" "validated prognostic favorable (1.34e-5)" "validated prognostic favorable (6.40e-4)" "unprognostic (1.26e-1)" "unprognostic (4.72e-2)" "unprognostic (4.47e-2)" "unprognostic (2.09e-1)" "unprognostic (2.35e-1)" "unprognostic (1.70e-1)" "unprognostic (5.34e-3)" "unprognostic (2.04e-2)" "unprognostic (1.48e-1)" "unprognostic (3.41e-1)" "unprognostic (3.34e-2)" "unprognostic (1.77e-1)" "unprognostic (4.12e-2)" "unprognostic (4.52e-2)" "unprognostic (3.79e-3)" "unprognostic (1.60e-1)" "unprognostic (1.57e-1)" "unprognostic (5.54e-2)" "unprognostic (7.66e-2)" BRD2 "BRD2-IT1, D6S113E, FSRG1, KIAA9001, NAT, RING3" ENSG00000204256 "Bromodomain containing 2" P25440 6 32968594-32981505 "Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 154.0;Epididymal basal cells: 231.9;Epididymal principal cells: 268.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042816, HPA074612" Approved Enhanced "Nucleoplasm,Nuclear speckles" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 8: Pancreas - Proteolysis" "Cluster 55: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 20: Non-specific - Transcription regulation" 84 "Nucleoplasm, Nuclear speckles" "HPA042816: , HPA074612: " "unprognostic (4.68e-2)" "unprognostic (4.90e-2)" "unprognostic (3.43e-1)" "unprognostic (1.72e-2)" "unprognostic (1.79e-1)" "unprognostic (1.92e-2)" "unprognostic (1.11e-1)" "unprognostic (1.73e-1)" "unprognostic (1.36e-1)" "unprognostic (8.00e-2)" "potential prognostic favorable (1.83e-7)" "unprognostic (3.88e-3)" "unprognostic (1.26e-1)" "unprognostic (2.74e-1)" "unprognostic (4.09e-1)" "potential prognostic unfavorable (6.12e-4)" "unprognostic (4.00e-2)" "unprognostic (1.40e-2)" "unprognostic (2.12e-2)" "unprognostic (3.23e-1)" "unprognostic (4.22e-2)" "unprognostic (4.93e-2)" "unprognostic (1.05e-2)" "unprognostic (9.52e-2)" "unprognostic (8.31e-2)" "unprognostic (2.65e-1)" "unprognostic (1.53e-2)" "unprognostic (5.37e-2)" "unprognostic (1.22e-1)" "unprognostic (2.50e-2)" "unprognostic (2.67e-1)" BRD3 "KIAA0043, ORFX, RING3L" ENSG00000169925 "Bromodomain containing 3" Q15059 9 134030305-134068535 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Platelets: 238.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051830, HPA076873" Approved Supported Nucleoplasm NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 47: Platelets - Hemostasis" 86 Nucleoplasm "HPA051830: , HPA076873: " "unprognostic (4.17e-2)" "unprognostic (2.02e-2)" "unprognostic (2.73e-1)" "unprognostic (2.55e-1)" "unprognostic (2.43e-2)" "unprognostic (7.61e-3)" "unprognostic (4.32e-2)" "unprognostic (7.31e-2)" "unprognostic (2.42e-2)" "unprognostic (6.47e-2)" "potential prognostic favorable (2.53e-4)" "unprognostic (2.91e-3)" "unprognostic (2.43e-1)" "unprognostic (1.21e-2)" "unprognostic (8.94e-2)" "unprognostic (1.31e-1)" "unprognostic (5.82e-2)" "unprognostic (1.73e-1)" "unprognostic (5.73e-2)" "unprognostic (4.20e-2)" "unprognostic (1.32e-1)" "unprognostic (2.50e-1)" "unprognostic (2.88e-1)" "unprognostic (1.15e-1)" "unprognostic (2.78e-2)" "unprognostic (2.41e-2)" "unprognostic (3.99e-2)" "unprognostic (3.52e-2)" "unprognostic (1.92e-2)" "unprognostic (7.03e-2)" "unprognostic (1.45e-2)" BRD3OS "bA374P20.3, FLJ35348, LINC00094, NCRNA00094, SERLOC" ENSG00000235106 "BRD3 opposite strand" A0A1B0GUI7 9 134025481-134034666 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 49.1;Platelets: 83.3;Respiratory ciliated cells: 46.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen), Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" HPA045437 Approved Nucleoplasm,Nucleoli,Vesicles,Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 108: Fibroblasts - ECM organization" "Nucleoplasm, Nucleoli" "Vesicles, Cytosol" "HPA045437: " "unprognostic (3.75e-1)" "unprognostic (4.79e-3)" "unprognostic (2.94e-1)" "unprognostic (3.55e-1)" "unprognostic (6.07e-2)" "unprognostic (3.53e-1)" "unprognostic (7.40e-2)" "unprognostic (4.83e-2)" "unprognostic (3.48e-3)" "potential prognostic favorable (6.06e-9)" "unprognostic (5.11e-3)" "unprognostic (8.37e-2)" "unprognostic (9.65e-2)" "unprognostic (1.20e-1)" "unprognostic (3.52e-2)" "potential prognostic unfavorable (8.56e-4)" "unprognostic (1.24e-1)" "unprognostic (1.65e-1)" "unprognostic (2.99e-1)" "unprognostic (2.34e-2)" "unprognostic (4.14e-1)" "unprognostic (5.03e-2)" "unprognostic (6.42e-2)" "potential prognostic favorable (8.25e-4)" "unprognostic (1.20e-1)" "unprognostic (2.25e-1)" "unprognostic (1.32e-1)" "unprognostic (1.55e-1)" "unprognostic (2.06e-2)" BRD4 "CAP, HUNK1, HUNKI, MCAP" ENSG00000141867 "Bromodomain containing 4" O60885 19 15235519-15332545 "Cancer-related genes, Disease related genes, Essential proteins, Predicted intracellular proteins" "DNA damage, Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 663.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015055, HPA061646, CAB068177, CAB068178" Supported Enhanced "Nucleoplasm,Mitotic chromosome" Yes NA "Cluster 20: Non-specific - DNA binding" "Cluster 24: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 23: Non-specific - Transcription" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 502 Nucleoplasm "Mitotic chromosome" "CAB068177: , CAB068178: , HPA015055: , HPA061646: " "unprognostic (1.46e-2)" "unprognostic (8.65e-3)" "unprognostic (6.43e-2)" "unprognostic (1.10e-1)" "unprognostic (1.07e-1)" "unprognostic (4.89e-1)" "unprognostic (2.51e-1)" "unprognostic (5.47e-2)" "unprognostic (1.52e-1)" "unprognostic (5.03e-3)" "unprognostic (2.12e-1)" "unprognostic (9.62e-2)" "unprognostic (1.38e-1)" "unprognostic (8.96e-3)" "unprognostic (6.67e-2)" "unprognostic (3.04e-2)" "unprognostic (1.51e-2)" "unprognostic (1.75e-1)" "unprognostic (3.87e-3)" "unprognostic (1.02e-3)" "unprognostic (2.87e-1)" "unprognostic (1.70e-1)" "unprognostic (1.14e-3)" "unprognostic (1.01e-1)" "unprognostic (1.10e-1)" "unprognostic (1.48e-2)" "unprognostic (2.34e-2)" "unprognostic (6.86e-3)" "unprognostic (2.29e-1)" "unprognostic (3.64e-2)" "unprognostic (2.58e-1)" BRD7 "BP75, CELTIX1, SMARCI1" ENSG00000166164 "Bromodomain containing 7" Q9NPI1 16 50313487-50368988 "Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation, Wnt signaling pathway" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "HPA042389, CAB046458, HPA060171" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 41: Basophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 82 Nucleoplasm Cytosol "CAB046458: , HPA042389: , HPA060171: " "unprognostic (5.94e-2)" "unprognostic (1.02e-2)" "unprognostic (6.79e-2)" "unprognostic (1.26e-2)" "unprognostic (2.22e-1)" "unprognostic (1.12e-1)" "unprognostic (1.15e-1)" "potential prognostic favorable (1.67e-4)" "unprognostic (1.92e-1)" "unprognostic (1.99e-2)" "unprognostic (5.45e-2)" "unprognostic (6.99e-2)" "unprognostic (1.76e-2)" "potential prognostic unfavorable (7.78e-4)" "unprognostic (4.36e-3)" "unprognostic (1.42e-1)" "unprognostic (2.49e-2)" "unprognostic (2.98e-1)" "unprognostic (4.22e-2)" "unprognostic (2.23e-2)" "unprognostic (2.34e-2)" "unprognostic (1.71e-1)" "unprognostic (4.63e-2)" "unprognostic (2.25e-1)" "unprognostic (1.31e-1)" "unprognostic (2.23e-1)" "unprognostic (3.71e-2)" "unprognostic (1.59e-1)" "unprognostic (4.75e-2)" "unprognostic (1.91e-1)" "unprognostic (7.22e-2)" BRD8 "p120, SMAP" ENSG00000112983 "Bromodomain containing 8" Q9H0E9 5 138139770-138178953 "Essential proteins, Predicted intracellular proteins" "Growth regulation, Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 220.7;Late primary spermatocytes: 315.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001841 Supported Supported Nucleoplasm,Mitochondria NA Yes "Cluster 35: Neutrophils - Protein binding" "Cluster 21: Testis - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 3: Early primary spermatocytes - Early meiosis" 50 Nucleoplasm Mitochondria "HPA001841: " "unprognostic (2.23e-1)" "unprognostic (4.32e-2)" "unprognostic (8.07e-2)" "unprognostic (1.76e-1)" "unprognostic (9.61e-2)" "unprognostic (4.35e-3)" "unprognostic (3.48e-1)" "unprognostic (1.76e-1)" "unprognostic (1.36e-1)" "unprognostic (4.05e-3)" "validated prognostic favorable (8.06e-4)" "validated prognostic favorable (2.88e-4)" "unprognostic (2.91e-1)" "potential prognostic unfavorable (6.48e-6)" "unprognostic (3.00e-2)" "unprognostic (3.11e-1)" "unprognostic (1.71e-1)" "unprognostic (8.75e-2)" "unprognostic (2.43e-1)" "unprognostic (8.16e-2)" "unprognostic (8.99e-2)" "unprognostic (6.95e-2)" "unprognostic (7.61e-3)" "unprognostic (8.33e-2)" "potential prognostic favorable (2.57e-4)" "unprognostic (3.76e-2)" "unprognostic (1.01e-1)" "unprognostic (2.50e-1)" "unprognostic (2.25e-1)" "unprognostic (7.17e-2)" "unprognostic (1.83e-1)" BRD9 "FLJ13441, SMARCI2" ENSG00000028310 "Bromodomain containing 9" Q9H8M2 5 850291-892801 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 196.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021465, HPA023197" Uncertain Enhanced Nucleoplasm NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 29: Non-specific - Unknown function" "Cluster 9: T-cells - Adaptive immunity: Regulation" 28 Nucleoplasm "HPA021465: , HPA023197: " "potential prognostic unfavorable (2.44e-5)" "unprognostic (4.55e-2)" "unprognostic (1.43e-1)" "unprognostic (1.71e-1)" "unprognostic (1.40e-1)" "unprognostic (2.42e-1)" "unprognostic (6.30e-2)" "potential prognostic favorable (2.19e-4)" "unprognostic (1.92e-1)" "unprognostic (2.91e-2)" "unprognostic (1.10e-1)" "unprognostic (9.44e-2)" "unprognostic (1.65e-1)" "potential prognostic unfavorable (3.59e-7)" "unprognostic (4.98e-3)" "unprognostic (9.30e-2)" "unprognostic (5.98e-3)" "unprognostic (7.10e-2)" "unprognostic (3.77e-2)" "unprognostic (1.12e-1)" "unprognostic (2.54e-3)" "unprognostic (1.59e-1)" "unprognostic (1.26e-3)" "unprognostic (6.67e-2)" "unprognostic (1.83e-1)" "unprognostic (1.14e-1)" "unprognostic (7.14e-2)" "unprognostic (2.19e-1)" "unprognostic (1.45e-1)" "unprognostic (2.76e-1)" "unprognostic (2.71e-2)" BRDT "BRD6, CT9" ENSG00000137948 "Bromodomain testis associated" Q58F21 1 91949343-92014426 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Meiosis, mRNA processing, mRNA splicing, Spermatogenesis, Transcription, Transcription regulation" "Activator, Chromatin regulator" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 48 "testis: 122.8" "Group enriched" "Detected in some" 6 "Early spermatids: 1248.0;Late primary spermatocytes: 1641.7" "Low cell type specificity" "Detected in some" "Cancer enriched" "Detected in many" 4 "Testicular Germ Cell Tumor (TCGA): 22.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.4" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.4" "Cancer enhanced" "Detected in some" "Esophageal cancer: 9.1" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Not detected" "Not detected" CAB012237 Approved NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 9: Non-specific - Receptor signaling" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 2 "CAB012237: " "unprognostic (2.55e-2)" "unprognostic (2.29e-1)" "unprognostic (3.71e-1)" "unprognostic (2.30e-3)" "unprognostic (7.62e-2)" "unprognostic (1.17e-3)" "unprognostic (1.44e-3)" "unprognostic (2.05e-1)" "unprognostic (8.73e-2)" "unprognostic (1.32e-1)" "unprognostic (6.48e-3)" "unprognostic (7.05e-2)" "unprognostic (4.96e-2)" "unprognostic (7.22e-2)" "unprognostic (3.24e-1)" "unprognostic (1.48e-1)" BRF1 "BRF, GTF3B, hBRF, TAF3B2, TAF3C, TFIIIB90" ENSG00000185024 "BRF1 RNA polymerase III transcription initiation factor subunit" Q92994 14 105209286-105315589 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pituitary gland - Corticotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051918, HPA074990" Approved Approved "Nucleoplasm,Nuclear bodies" Yes No "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 19 "Nucleoplasm, Nuclear bodies" "HPA051918: , HPA074990: " "unprognostic (2.20e-1)" "unprognostic (3.53e-1)" "unprognostic (7.31e-2)" "unprognostic (7.59e-2)" "unprognostic (2.34e-1)" "unprognostic (2.51e-1)" "unprognostic (1.86e-1)" "unprognostic (2.35e-2)" "unprognostic (1.27e-1)" "unprognostic (1.34e-3)" "potential prognostic favorable (1.76e-6)" "unprognostic (4.99e-3)" "unprognostic (9.12e-2)" "potential prognostic unfavorable (4.55e-5)" "unprognostic (5.66e-2)" "unprognostic (5.02e-3)" "unprognostic (1.40e-1)" "unprognostic (4.25e-2)" "unprognostic (4.96e-2)" "unprognostic (1.80e-1)" "unprognostic (1.23e-1)" "potential prognostic favorable (1.98e-5)" "unprognostic (5.22e-2)" "unprognostic (5.06e-2)" "unprognostic (2.89e-2)" "unprognostic (1.19e-1)" "unprognostic (1.79e-1)" "unprognostic (7.33e-2)" "unprognostic (1.36e-1)" "unprognostic (2.18e-2)" "unprognostic (1.38e-1)" BRF2 "BRFU, FLJ11052, TFIIIB50" ENSG00000104221 "BRF2 RNA polymerase III transcription initiation factor subunit" Q9HAW0 8 37843268-37849861 "Essential proteins, Predicted intracellular proteins" "Stress response, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 29.6;Endometrial luminal cells: 51.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019269, HPA023378" Supported Supported Nucleoli NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 5 Nucleoli "CAB019269: , HPA023378: " "potential prognostic favorable (2.59e-4)" "unprognostic (2.33e-3)" "unprognostic (2.52e-2)" "unprognostic (5.27e-1)" "unprognostic (5.64e-2)" "unprognostic (3.28e-2)" "unprognostic (1.86e-1)" "unprognostic (3.34e-3)" "unprognostic (7.51e-3)" "unprognostic (1.01e-2)" "unprognostic (9.81e-3)" "potential prognostic favorable (3.89e-4)" "unprognostic (7.69e-2)" "unprognostic (2.29e-2)" "unprognostic (3.21e-1)" "unprognostic (2.28e-1)" "unprognostic (1.18e-1)" "unprognostic (1.11e-2)" "unprognostic (3.28e-3)" "unprognostic (1.78e-1)" "unprognostic (3.17e-2)" "unprognostic (3.31e-1)" "unprognostic (4.72e-1)" "unprognostic (2.36e-3)" "unprognostic (2.45e-2)" "unprognostic (1.03e-1)" "unprognostic (1.93e-2)" "unprognostic (1.48e-2)" "unprognostic (2.36e-1)" "unprognostic (5.00e-2)" "unprognostic (1.10e-1)" BRI3 ENSG00000164713 "Brain protein I3" O95415 7 98252379-98310441 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 685.8;Early spermatids: 687.5;Hofbauer cells: 909.0;Neutrophils: 1041.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 43.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042215 Uncertain NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 24: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 5 "HPA042215: " "unprognostic (2.01e-2)" "unprognostic (3.25e-1)" "unprognostic (1.37e-2)" "unprognostic (3.36e-2)" "unprognostic (6.39e-2)" "unprognostic (4.86e-2)" "potential prognostic unfavorable (7.49e-4)" "unprognostic (2.58e-2)" "potential prognostic unfavorable (1.73e-4)" "potential prognostic unfavorable (6.79e-5)" "potential prognostic favorable (7.27e-6)" "unprognostic (2.31e-1)" "unprognostic (2.05e-1)" "unprognostic (2.11e-3)" "potential prognostic unfavorable (5.84e-5)" "unprognostic (2.35e-1)" "unprognostic (3.36e-2)" "unprognostic (1.34e-1)" "unprognostic (2.61e-2)" "unprognostic (7.48e-2)" "unprognostic (8.87e-2)" "unprognostic (2.60e-2)" "unprognostic (1.91e-1)" "unprognostic (3.09e-1)" "unprognostic (5.18e-2)" "unprognostic (1.56e-1)" "unprognostic (1.37e-1)" "unprognostic (2.01e-1)" "unprognostic (5.55e-3)" "unprognostic (1.80e-1)" "unprognostic (1.62e-1)" BRI3BP "BNAS1, HCCR-2, HCCRBP-3, KG19" ENSG00000184992 "BRI3 binding protein" Q8WY22 12 124993645-125031231 "Predicted membrane proteins, Transporters" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 19.6" "Cell type enhanced" "Detected in many" "Late spermatids: 313.1;Monocyte progenitors: 129.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 13.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Sebaceous gland cells, Stomach - Mitotic cells (Stomach), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014957 Approved Approved Nucleoplasm,Mitochondria NA Yes "Cluster 22: Eosinophils - Transcription" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 38: Non-specific - Transcription" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 41 "Nucleoplasm, Mitochondria" "HPA014957: " "unprognostic (6.84e-2)" "unprognostic (2.72e-2)" "unprognostic (8.09e-2)" "unprognostic (2.38e-2)" "unprognostic (5.31e-3)" "unprognostic (2.66e-1)" "unprognostic (2.89e-2)" "unprognostic (1.79e-2)" "unprognostic (8.43e-2)" "unprognostic (3.61e-3)" "potential prognostic favorable (1.36e-5)" "unprognostic (2.19e-2)" "unprognostic (2.00e-1)" "validated prognostic unfavorable (1.17e-4)" "validated prognostic unfavorable (4.88e-5)" "unprognostic (1.48e-3)" "unprognostic (1.08e-2)" "unprognostic (4.63e-1)" "unprognostic (6.75e-2)" "unprognostic (2.21e-2)" "unprognostic (1.28e-1)" "unprognostic (2.74e-1)" "potential prognostic favorable (3.27e-5)" "unprognostic (7.85e-2)" "unprognostic (1.14e-1)" "unprognostic (1.02e-1)" "unprognostic (4.03e-2)" "potential prognostic favorable (6.04e-4)" "unprognostic (1.89e-1)" "unprognostic (4.25e-2)" "unprognostic (3.35e-1)" BRICD5 "C16orf79, MGC21830" ENSG00000182685 "BRICHOS domain containing 5" Q6PL45 16 2209253-2210905 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "brain: 119.3" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 10.4;Late spermatids: 14.8;Retinal amacrine cells: 8.8;Sertoli cells: 18.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "spinal cord: 4.0" HPA063522 Approved "Nucleoplasm,Actin filaments" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 71: Cerebellum - Nervous system development" "Cluster 15: Non-specific - Transcription" "Cluster 35: RS4;11 - Unknown function" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 3 "Actin filaments" Nucleoplasm "HPA063522: " "unprognostic (4.01e-2)" "unprognostic (5.30e-3)" "unprognostic (1.27e-1)" "unprognostic (1.10e-2)" "unprognostic (4.68e-2)" "unprognostic (1.95e-1)" "potential prognostic favorable (4.78e-4)" "unprognostic (1.06e-2)" "unprognostic (9.89e-2)" "potential prognostic unfavorable (5.42e-7)" "unprognostic (1.14e-1)" "unprognostic (6.20e-2)" "unprognostic (9.38e-2)" "unprognostic (6.18e-2)" "unprognostic (1.92e-1)" "unprognostic (2.22e-1)" "unprognostic (3.46e-2)" "unprognostic (7.93e-2)" "unprognostic (3.15e-2)" "unprognostic (3.44e-3)" "unprognostic (4.39e-2)" "unprognostic (2.87e-2)" "unprognostic (2.74e-1)" "unprognostic (4.99e-2)" "unprognostic (1.14e-3)" "unprognostic (2.27e-1)" "unprognostic (1.98e-1)" "unprognostic (2.79e-1)" "unprognostic (1.28e-1)" BRINP1 "DBC1, DBCCR1, FAM5A" ENSG00000078725 "BMP/retinoic acid inducible neural specific 1" O60477 9 119153458-119369435 "Predicted intracellular proteins, Transporters" "Cell cycle, Growth arrest, Neurogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 37.8" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 127.6;Astrocytes: 322.4;Brain excitatory neurons: 326.3;Brain inhibitory neurons: 218.1;Breast lactating cells: 654.7;Breast myoepithelial cells: 144.7;Cone photoreceptor cells: 184.2;Endometrial stromal cells: 118.6;Oligodendrocyte progenitor cells: 310.5;Oligodendrocytes: 140.3;Other brain neurons: 182.0;Retinal amacrine cells: 197.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 5.5" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pituitary gland - Somatotropes, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038828 Approved Uncertain Microtubules "Intracellular and membrane" Other NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 35: Neurons - Synaptic function & neurogenesis" 6 Microtubules "HPA038828: " "potential prognostic favorable (1.38e-4)" "unprognostic (1.32e-1)" "unprognostic (9.71e-2)" "unprognostic (1.17e-1)" "potential prognostic favorable (9.85e-4)" "unprognostic (2.46e-1)" "unprognostic (1.22e-1)" "unprognostic (2.10e-2)" "unprognostic (2.57e-2)" "unprognostic (2.15e-2)" "unprognostic (5.04e-2)" "unprognostic (1.27e-2)" "unprognostic (2.05e-1)" "unprognostic (2.01e-1)" BRINP2 "DBCCR1L2, FAM5B" ENSG00000198797 "BMP/retinoic acid inducible neural specific 2" Q9C0B6 1 177170958-177282422 "Predicted secreted proteins, Transporters" "Cell cycle, Growth arrest" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "adrenal gland: 8.5;brain: 27.2" "Cell type enhanced" "Detected in some" "Adrenal cortex cells: 53.7;Adrenal medulla cells: 74.5;Astrocytes: 175.9;Brain excitatory neurons: 112.7;Brain inhibitory neurons: 75.5;Epicardial cells: 38.7;Gonadotrophs: 60.8;Mesothelial cells: 34.4;Microglia: 34.1;Oligodendrocyte progenitor cells: 139.9;Oligodendrocytes: 37.9;Other brain neurons: 59.2;Pituitary stem cells: 116.9;Retinal amacrine cells: 43.4;Retinal horizontal cells: 34.1" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in some" 7 "Glioblastoma Multiforme (TCGA): 15.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050681 Uncertain "Secreted in other tissues" Other NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 109: Neurons - Neuronal signaling" "HPA050681: " "unprognostic (1.73e-1)" "unprognostic (2.69e-1)" "unprognostic (3.55e-2)" "unprognostic (2.65e-1)" BRINP3 "DBCCR1L, DBCCR1L1, FAM5C" ENSG00000162670 "BMP/retinoic acid inducible neural specific 3" Q76B58 1 190097658-190478404 "Predicted intracellular proteins, Predicted secreted proteins" "Cell cycle, Growth arrest" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.9;intestine: 16.8" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 202.1;Astrocytes: 374.6;Bergmann glia: 506.4;Brain excitatory neurons: 388.8;Brain inhibitory neurons: 238.4;Enterocytes: 258.5;Neuroendocrine cells: 175.8;Oligodendrocyte progenitor cells: 1626.1;Other brain neurons: 518.6;Paneth cells: 224.3;Prostatic glandular cells: 373.5" "Cell type enhanced" "Detected in all" "oligodendrocyte precursor cell: 1923.9" "Group enriched" "Detected in some" 9 "Breast Invasive Carcinoma (TCGA): 6.8;Glioblastoma Multiforme (TCGA): 21.1;Prostate Adenocarcinoma (TCGA): 7.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 11.2;Rhabdoid: 20.8" "Lung - Fibroblasts_2, Prostate - Prostate glandular cells, Testis - Early spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054693 Uncertain "Secreted in other tissues" Other NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 27: Breast cancer - Unknown function" "Cluster 109: Neurons - Neuronal signaling" "HPA054693: " "unprognostic (1.20e-1)" "unprognostic (1.57e-2)" "unprognostic (3.25e-1)" "unprognostic (8.67e-2)" "unprognostic (3.97e-1)" "unprognostic (7.77e-3)" "unprognostic (9.74e-2)" "unprognostic (1.96e-2)" "unprognostic (3.29e-1)" "unprognostic (2.67e-1)" BRIP1 "BACH1, FANCJ, OF" ENSG00000136492 "BRCA1 interacting helicase 1" Q9BX63 17 61679139-61863559 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "Helicase, Hydrolase, Isomerase" "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 2.6;lymphoid tissue: 3.4" "Cell type enhanced" "Detected in many" "Early spermatids: 194.4;Erythrocyte progenitors: 195.1;Late primary spermatocytes: 153.1;Late spermatids: 296.3;Megakaryocyte progenitors: 177.1;Megakaryocyte-Erythroid progenitors: 84.7;Monocyte progenitors: 174.6;Neutrophil progenitors: 194.5;Paneth cells: 73.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Heart muscle - Mitotic cells (Heart), Liver - Hepatocytes, Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA005474 Approved Supported "Nucleoplasm,Nuclear membrane" NA Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 9: Non-specific - Receptor signaling" "Cluster 27: Breast cancer - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 27 "Nucleoplasm, Nuclear membrane" "HPA005474: " "unprognostic (2.79e-1)" "unprognostic (1.47e-1)" "unprognostic (3.76e-1)" "unprognostic (4.34e-2)" "unprognostic (9.71e-2)" "unprognostic (9.69e-2)" "unprognostic (4.95e-1)" "unprognostic (6.35e-2)" "unprognostic (6.97e-3)" "unprognostic (1.63e-3)" "unprognostic (2.44e-2)" "unprognostic (4.09e-3)" "unprognostic (5.89e-3)" "unprognostic (3.20e-3)" "potential prognostic unfavorable (6.97e-4)" "unprognostic (4.11e-3)" "unprognostic (6.92e-2)" "unprognostic (2.82e-2)" "unprognostic (1.46e-1)" "unprognostic (1.32e-1)" "potential prognostic unfavorable (1.72e-4)" "unprognostic (1.05e-2)" "unprognostic (4.13e-3)" "unprognostic (2.58e-3)" "unprognostic (9.54e-3)" "unprognostic (2.49e-2)" "unprognostic (2.97e-1)" "unprognostic (2.12e-1)" BRIX1 "BRIX, BXDC2, FLJ11100" ENSG00000113460 "Biogenesis of ribosomes BRX1" Q8TDN6 5 34915677-34925996 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 156.7;Migrating cytotrophoblasts: 169.0;Oocytes: 543.4;Syncytiotrophoblasts: 164.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039614 Enhanced "Nucleoli,Mitotic chromosome" Yes No 11000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 29: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 90 "Nucleoli, Mitotic chromosome" "HPA039614: " "unprognostic (3.13e-1)" "potential prognostic unfavorable (6.98e-4)" "unprognostic (1.89e-3)" "unprognostic (1.52e-1)" "unprognostic (1.71e-1)" "unprognostic (6.15e-2)" "unprognostic (4.30e-1)" "unprognostic (3.53e-1)" "unprognostic (4.57e-2)" "unprognostic (7.37e-3)" "unprognostic (3.74e-2)" "unprognostic (1.29e-1)" "potential prognostic unfavorable (8.03e-6)" "validated prognostic unfavorable (4.30e-9)" "validated prognostic unfavorable (1.11e-4)" "unprognostic (2.45e-3)" "unprognostic (2.52e-3)" "unprognostic (3.38e-2)" "unprognostic (8.15e-2)" "unprognostic (5.32e-2)" "unprognostic (2.36e-2)" "potential prognostic unfavorable (1.72e-4)" "unprognostic (3.70e-3)" "unprognostic (3.37e-2)" "unprognostic (1.93e-1)" "unprognostic (1.85e-1)" "unprognostic (1.15e-2)" "unprognostic (7.51e-2)" "unprognostic (2.16e-1)" "unprognostic (2.43e-1)" "unprognostic (9.31e-3)" BRK1 "C3orf10, HSPC300, MDS027" ENSG00000254999 "BRICK1 subunit of SCAR/WAVE actin nucleating complex" Q8WUW1 3 10115675-10127190 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 1131.1;Esophageal apical cells: 1839.9;Esophageal suprabasal cells: 870.9;Late spermatids: 3909.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060391 Approved "Nuclear speckles,Cell Junctions" NA NA 88000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 14: Neurons - Synaptic function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 71 "Nuclear speckles" "Cell Junctions" "HPA060391: " "unprognostic (1.81e-3)" "unprognostic (2.76e-2)" "unprognostic (1.65e-1)" "unprognostic (4.76e-3)" "unprognostic (2.02e-1)" "unprognostic (8.02e-3)" "unprognostic (4.97e-2)" "unprognostic (6.30e-2)" "potential prognostic unfavorable (9.00e-6)" "potential prognostic favorable (8.81e-6)" "unprognostic (3.22e-3)" "unprognostic (2.75e-2)" "validated prognostic unfavorable (6.94e-7)" "validated prognostic unfavorable (4.59e-7)" "unprognostic (3.06e-1)" "unprognostic (1.60e-1)" "unprognostic (6.58e-2)" "unprognostic (8.45e-2)" "unprognostic (3.08e-2)" "unprognostic (1.00e-2)" "unprognostic (2.97e-1)" "unprognostic (2.61e-1)" "unprognostic (2.42e-2)" "unprognostic (1.45e-1)" "unprognostic (1.24e-1)" "unprognostic (2.92e-1)" "unprognostic (8.73e-2)" "unprognostic (3.03e-1)" "unprognostic (2.43e-1)" "unprognostic (1.30e-2)" BRME1 "C19orf57, MEIOK21, MGC11271" ENSG00000132016 "Break repair meiotic recombinase recruitment factor 1" Q0VDD7 19 13882348-13906452 "Predicted intracellular proteins" Meiosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 13.5" "Cell type enhanced" "Detected in some" "Astrocytes: 3.0;Bergmann glia: 3.9;Brain excitatory neurons: 3.0;Differentiating spermatogonia: 3.3;Early primary spermatocytes: 17.2;Oligodendrocyte progenitor cells: 2.9;Oligodendrocytes: 3.0;Tuft cells: 11.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044012, HPA054615" Enhanced Approved Nucleoplasm NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 67: Testis - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 3: Early primary spermatocytes - Early meiosis" 26 Nucleoplasm "HPA044012: , HPA054615: " "unprognostic (1.84e-3)" "unprognostic (3.77e-1)" "unprognostic (3.37e-2)" "unprognostic (1.41e-1)" "unprognostic (1.46e-1)" "unprognostic (2.75e-1)" "unprognostic (5.32e-2)" "potential prognostic favorable (1.39e-4)" "potential prognostic unfavorable (4.83e-4)" "unprognostic (2.35e-2)" "unprognostic (1.15e-2)" "unprognostic (6.72e-2)" "unprognostic (2.85e-3)" "unprognostic (8.05e-3)" "unprognostic (9.36e-2)" "unprognostic (7.12e-2)" "unprognostic (2.88e-1)" "unprognostic (7.87e-3)" "unprognostic (5.05e-2)" "unprognostic (2.68e-2)" "unprognostic (7.10e-2)" "unprognostic (2.16e-3)" "unprognostic (2.65e-2)" "unprognostic (2.07e-1)" BRMS1 DKFZP564A063 ENSG00000174744 "BRMS1 transcriptional repressor and anoikis regulator" Q9HCU9 11 66337333-66345125 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" Repressor "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 129.2;Oocytes: 124.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Macrophages, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010824, HPA019637" Approved Approved Centrosome NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 24: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 50 Centrosome "CAB010824: , HPA019637: " "unprognostic (6.10e-2)" "unprognostic (6.33e-2)" "unprognostic (6.09e-2)" "unprognostic (1.22e-1)" "unprognostic (1.17e-1)" "unprognostic (1.91e-1)" "unprognostic (1.56e-1)" "unprognostic (3.40e-1)" "unprognostic (1.13e-1)" "unprognostic (2.37e-3)" "unprognostic (2.44e-2)" "unprognostic (4.97e-2)" "unprognostic (3.31e-3)" "potential prognostic unfavorable (2.73e-4)" "unprognostic (2.49e-3)" "unprognostic (1.08e-3)" "potential prognostic unfavorable (6.86e-4)" "unprognostic (5.77e-2)" "unprognostic (4.02e-1)" "unprognostic (2.41e-1)" "unprognostic (2.27e-1)" "unprognostic (2.14e-1)" "unprognostic (1.85e-1)" "unprognostic (4.10e-1)" "unprognostic (5.28e-2)" "unprognostic (4.45e-2)" "unprognostic (1.95e-1)" "unprognostic (4.68e-3)" "unprognostic (2.09e-1)" "unprognostic (2.62e-2)" "unprognostic (8.33e-2)" BRMS1L "BRMS1, FLJ39177, MGC11296" ENSG00000100916 "BRMS1 like transcriptional repressor" Q5PSV4 14 35826338-35932325 "Predicted intracellular proteins" "Growth regulation, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046623 Uncertain Supported Nucleoplasm NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 20: Non-specific - Transcription regulation" 44 Nucleoplasm "HPA046623: " "unprognostic (1.37e-1)" "unprognostic (1.01e-3)" "unprognostic (2.04e-1)" "unprognostic (7.22e-2)" "unprognostic (3.93e-3)" "unprognostic (1.31e-2)" "unprognostic (4.06e-2)" "unprognostic (6.86e-3)" "unprognostic (1.61e-1)" "unprognostic (3.60e-1)" "potential prognostic favorable (7.30e-8)" "unprognostic (2.41e-3)" "unprognostic (2.35e-1)" "potential prognostic unfavorable (1.22e-4)" "unprognostic (1.02e-2)" "unprognostic (1.28e-1)" "unprognostic (9.87e-2)" "unprognostic (8.98e-2)" "unprognostic (2.34e-1)" "unprognostic (1.69e-1)" "unprognostic (3.27e-2)" "unprognostic (7.34e-2)" "unprognostic (4.20e-3)" "unprognostic (2.56e-2)" "unprognostic (3.32e-1)" "unprognostic (2.68e-2)" "unprognostic (1.24e-1)" "unprognostic (1.00e-3)" "unprognostic (2.67e-1)" "unprognostic (7.27e-2)" "unprognostic (1.05e-1)" BROX "C1orf58, FLJ32421" ENSG00000162819 "BRO1 domain and CAAX motif containing" Q5VW32 1 222712553-222735196 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 223.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031445 Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 150000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 3 "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA031445: " "unprognostic (1.06e-2)" "unprognostic (4.61e-2)" "unprognostic (1.75e-2)" "unprognostic (1.37e-1)" "unprognostic (2.13e-2)" "unprognostic (1.45e-1)" "unprognostic (1.39e-1)" "unprognostic (4.80e-2)" "potential prognostic unfavorable (4.84e-4)" "potential prognostic favorable (1.05e-6)" "unprognostic (1.44e-1)" "unprognostic (1.31e-2)" "unprognostic (7.37e-2)" "unprognostic (1.86e-1)" "unprognostic (1.29e-1)" "unprognostic (3.30e-1)" "unprognostic (3.80e-2)" "unprognostic (2.17e-1)" "unprognostic (1.40e-1)" "potential prognostic unfavorable (6.32e-5)" "unprognostic (3.88e-2)" "unprognostic (3.19e-1)" "unprognostic (1.55e-2)" "unprognostic (1.19e-1)" "unprognostic (7.20e-2)" "unprognostic (1.58e-1)" "unprognostic (2.02e-2)" "unprognostic (1.68e-1)" "unprognostic (7.00e-3)" "unprognostic (1.45e-1)" BRPF1 BR140 ENSG00000156983 "Bromodomain and PHD finger containing 1" P55201 3 9731729-9748019 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator, DNA-binding" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 22.3" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003359, CAB080429" Enhanced Supported Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 15: Non-specific - Transcription" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 33 Nucleoplasm "CAB080429: , HPA003359: " "unprognostic (1.74e-1)" "unprognostic (1.97e-2)" "unprognostic (1.99e-1)" "unprognostic (1.92e-1)" "unprognostic (6.75e-2)" "unprognostic (3.50e-3)" "unprognostic (2.73e-1)" "potential prognostic favorable (1.10e-4)" "unprognostic (3.93e-3)" "unprognostic (1.55e-2)" "potential prognostic favorable (1.35e-4)" "unprognostic (7.78e-2)" "unprognostic (4.11e-2)" "potential prognostic unfavorable (3.89e-5)" "unprognostic (1.24e-1)" "unprognostic (6.54e-2)" "unprognostic (8.81e-3)" "unprognostic (1.00e-1)" "unprognostic (2.95e-2)" "unprognostic (1.16e-2)" "unprognostic (6.32e-2)" "unprognostic (1.04e-1)" "unprognostic (1.06e-1)" "potential prognostic unfavorable (3.60e-4)" "unprognostic (1.01e-2)" "unprognostic (2.35e-1)" "unprognostic (2.55e-1)" "unprognostic (8.10e-2)" "unprognostic (1.36e-1)" "unprognostic (1.22e-1)" "unprognostic (1.12e-1)" BRPF3 KIAA1286 ENSG00000096070 "Bromodomain and PHD finger containing 3" Q9ULD4 6 36196744-36232790 "Plasma proteins, Predicted intracellular proteins" "Chromatin regulator" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022787 Uncertain Approved Nucleoplasm,Mitochondria No No "Cluster 42: Non-specific - Vesicular transport" "Cluster 61: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 16 Nucleoplasm Mitochondria "HPA022787: " "unprognostic (7.72e-2)" "unprognostic (5.65e-2)" "unprognostic (1.57e-1)" "unprognostic (1.29e-2)" "unprognostic (2.51e-1)" "unprognostic (4.16e-2)" "unprognostic (3.67e-1)" "unprognostic (4.50e-2)" "unprognostic (2.41e-2)" "unprognostic (2.82e-1)" "validated prognostic favorable (4.96e-7)" "validated prognostic favorable (6.19e-4)" "unprognostic (5.04e-2)" "unprognostic (1.63e-1)" "unprognostic (8.39e-2)" "unprognostic (1.49e-1)" "unprognostic (1.17e-2)" "unprognostic (8.21e-2)" "unprognostic (1.58e-1)" "unprognostic (4.84e-2)" "unprognostic (1.20e-1)" "unprognostic (2.90e-1)" "unprognostic (2.08e-2)" "unprognostic (1.76e-1)" "unprognostic (4.08e-2)" "unprognostic (9.46e-3)" "unprognostic (1.79e-2)" "unprognostic (2.45e-1)" "unprognostic (4.06e-1)" "unprognostic (1.48e-2)" "unprognostic (4.88e-2)" BRS3 "BB3, BB3R, BBR3" ENSG00000102239 "Bombesin receptor subtype 3" P32247 X 136487947-136493780 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "epididymis: 24.3" "Cell type enriched" "Detected in some" 9 "Epididymal principal cells: 134.3" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "hypothalamus: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Alpha cells, Skin - Hair cortex cells, Skin - Inner root sheath cells" "Region enriched" "Detected in some" 4 "hypothalamus: 6.1" "Region enhanced" "Detected in single" "basal ganglia: 2.4" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 40: Non-specific - Unknown function" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" BRSK1 "KIAA1811, SAD-B" ENSG00000160469 "BR serine/threonine kinase 1" Q8TDC3 19 55282072-55312562 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, DNA damage, Neurogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 191.3;pituitary gland: 49.5" "Cell type enhanced" "Detected in many" "Astrocytes: 24.8;Brain excitatory neurons: 43.8;Brain inhibitory neurons: 45.7;Lactotrophs: 28.8;Oligodendrocyte progenitor cells: 40.1;Oligodendrocytes: 62.2;Other brain neurons: 32.2;Plasma cells: 26.1;Retinal amacrine cells: 37.7;Retinal bipolar cells: 31.0;Retinal horizontal cells: 30.1;Somatotrophs: 23.6" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 37.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Neuroblastoma: 43.9" "Adipose subcutaneous - Smooth muscle cells, Colon - Enteric glia cells, Kidney - Fibroblasts, Lung - Smooth muscle cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021212, HPA061719" Enhanced Supported "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 2 Nucleoplasm "Vesicles, Plasma membrane" "HPA021212: , HPA061719: " "unprognostic (3.05e-2)" "unprognostic (4.00e-3)" "unprognostic (3.98e-1)" "unprognostic (1.33e-2)" "unprognostic (1.21e-1)" "unprognostic (3.99e-2)" "unprognostic (1.41e-1)" "unprognostic (2.36e-1)" "unprognostic (6.10e-2)" "potential prognostic unfavorable (1.85e-4)" "unprognostic (1.68e-3)" "unprognostic (2.06e-1)" "potential prognostic unfavorable (1.57e-6)" "unprognostic (2.21e-1)" "unprognostic (9.77e-2)" "unprognostic (1.14e-1)" "unprognostic (9.82e-2)" "unprognostic (1.95e-2)" "unprognostic (3.49e-1)" "unprognostic (1.21e-1)" "unprognostic (1.50e-3)" "unprognostic (6.81e-2)" "unprognostic (2.46e-1)" "unprognostic (2.00e-1)" "unprognostic (2.45e-1)" "unprognostic (5.33e-3)" "unprognostic (1.92e-1)" "unprognostic (2.89e-2)" "unprognostic (1.36e-1)" "unprognostic (1.79e-1)" BRSK2 "C11orf7, PEN11B, SAD-A, STK29" ENSG00000174672 "BR serine/threonine kinase 2" Q8IWQ3 11 1389899-1462689 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell cycle, Cell division, Exocytosis, Mitosis, Neurogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 96.9;pancreas: 97.0" "Cell type enhanced" "Detected in many" "Astrocytes: 30.1;Bergmann glia: 24.7;Brain excitatory neurons: 61.6;Brain inhibitory neurons: 46.8;Gonadotrophs: 35.9;Lactotrophs: 26.5;Müller glia: 23.7;Oligodendrocyte progenitor cells: 44.6;Oligodendrocytes: 34.2;Other brain neurons: 40.6;Pancreatic acinar cells: 47.1;Retinal amacrine cells: 45.5;Retinal bipolar cells: 67.9;Retinal horizontal cells: 42.1;Sertoli cells: 32.2;Thyrotrophs: 24.4;Vascular smooth muscle cells: 39.6" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 12.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 19.3" "Adrenal gland - Adrenal medulla cells, Spleen - Fibroblasts_2, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073690 Uncertain "Golgi apparatus" NA NA "Cluster 70: Non-specific - Protein processing" "Cluster 37: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 8 "Golgi apparatus" "HPA073690: " "unprognostic (1.97e-2)" "unprognostic (3.40e-2)" "unprognostic (3.91e-2)" "unprognostic (2.91e-1)" "unprognostic (2.17e-2)" "unprognostic (8.13e-2)" "unprognostic (3.97e-2)" "unprognostic (3.50e-1)" "unprognostic (3.07e-2)" "unprognostic (2.62e-2)" "unprognostic (1.58e-3)" "unprognostic (3.40e-1)" "unprognostic (9.89e-2)" "unprognostic (6.86e-2)" "unprognostic (3.24e-2)" "unprognostic (6.97e-3)" "unprognostic (1.13e-1)" "unprognostic (2.05e-1)" BRWD1 "C21orf107, DCAF19, FLJ11315, N143, WDR9" ENSG00000185658 "Bromodomain and WD repeat domain containing 1" Q9NSI6 21 39184176-39321559 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Ciliopathy, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027343, HPA030943, HPA030944, HPA030945, CAB034184" Approved Approved "Nucleoplasm,Nucleoli,Vesicles,Plasma membrane,Mitotic spindle,Cytosol" Yes NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 73: Brain - Neuronal signaling" "Cluster 31: Non-specific - Transcription" "Cluster 47: Leukemia - Hemostasis" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 8 "Nucleoplasm, Cytosol" "Nucleoli, Vesicles, Plasma membrane, Mitotic spindle" "CAB034184: , HPA027343: , HPA030943: , HPA030944: , HPA030945: " "unprognostic (1.69e-2)" "unprognostic (9.35e-2)" "unprognostic (5.01e-2)" "unprognostic (3.03e-2)" "unprognostic (6.37e-2)" "unprognostic (1.28e-1)" "unprognostic (2.20e-1)" "unprognostic (8.97e-3)" "unprognostic (1.20e-2)" "unprognostic (2.21e-1)" "unprognostic (1.27e-1)" "unprognostic (6.41e-2)" "unprognostic (1.11e-2)" "unprognostic (3.63e-3)" "unprognostic (6.07e-2)" "unprognostic (2.47e-1)" "unprognostic (5.58e-2)" "unprognostic (1.59e-1)" "unprognostic (1.05e-1)" "unprognostic (1.16e-1)" "unprognostic (6.06e-2)" "unprognostic (8.13e-2)" "unprognostic (2.36e-2)" "unprognostic (2.02e-1)" "unprognostic (7.24e-3)" "unprognostic (2.01e-1)" "unprognostic (3.94e-2)" "unprognostic (5.09e-2)" "unprognostic (7.05e-2)" "unprognostic (2.61e-2)" "unprognostic (2.21e-1)" BRWD3 "FLJ38568, MRX93" ENSG00000165288 "Bromodomain and WD repeat domain containing 3" Q6RI45 X 80669503-80809877 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Neutrophils: 372.7;Sertoli cells: 501.5" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 12.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012802 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 49: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 36: Non-specific - mRNA processing" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 6 Nucleoplasm Cytosol "HPA012802: " "unprognostic (2.45e-2)" "unprognostic (1.95e-2)" "unprognostic (3.59e-2)" "unprognostic (2.51e-1)" "unprognostic (5.31e-1)" "unprognostic (1.68e-1)" "unprognostic (4.32e-2)" "unprognostic (4.03e-3)" "unprognostic (7.96e-2)" "unprognostic (2.93e-1)" "potential prognostic favorable (6.33e-4)" "unprognostic (3.64e-2)" "unprognostic (6.88e-3)" "unprognostic (7.64e-2)" "unprognostic (1.93e-2)" "unprognostic (1.17e-1)" "unprognostic (7.07e-3)" "unprognostic (5.46e-2)" "unprognostic (5.77e-3)" "unprognostic (6.72e-2)" "unprognostic (4.26e-2)" "unprognostic (1.61e-1)" "unprognostic (5.14e-3)" "unprognostic (3.34e-2)" "unprognostic (4.78e-2)" "unprognostic (1.20e-1)" "unprognostic (9.44e-3)" "unprognostic (6.42e-2)" "unprognostic (2.83e-1)" "unprognostic (3.26e-2)" "unprognostic (1.33e-1)" BSCL2 "GNG3LG, seipin, SPG17" ENSG00000168000 "BSCL2 lipid droplet biogenesis associated, seipin" Q96G97 11 62689289-62709845 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid degradation, Lipid metabolism" "Congenital generalized lipodystrophy, Diabetes mellitus, Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 274.6;pituitary gland: 219.0" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 3.6;Early primary spermatocytes: 4.5;Early spermatids: 3.6;Epididymal principal cells: 4.3;Late primary spermatocytes: 7.0;Late spermatids: 13.8;Oocytes: 4.6;Parietal cells: 3.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Colon enteroendocrine cells, Kidney - Fibroblasts, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042394 Approved NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 22: Epididymis - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 29 "HPA042394: " "unprognostic (1.24e-2)" "unprognostic (2.32e-1)" "unprognostic (2.35e-2)" "unprognostic (2.07e-3)" "unprognostic (3.60e-2)" "unprognostic (1.26e-1)" "unprognostic (5.57e-3)" "unprognostic (1.07e-2)" "unprognostic (1.02e-1)" "unprognostic (7.29e-2)" "unprognostic (7.36e-3)" "unprognostic (3.89e-3)" "unprognostic (2.78e-3)" "unprognostic (3.92e-2)" "unprognostic (1.10e-2)" "unprognostic (3.42e-1)" "unprognostic (3.06e-2)" "unprognostic (1.54e-1)" "unprognostic (8.05e-3)" "unprognostic (1.62e-2)" "unprognostic (1.01e-1)" "unprognostic (5.01e-3)" "unprognostic (2.04e-2)" "unprognostic (2.97e-2)" "unprognostic (1.33e-3)" "unprognostic (7.80e-2)" "unprognostic (2.43e-1)" "unprognostic (1.04e-1)" "unprognostic (2.12e-1)" "unprognostic (3.18e-1)" "unprognostic (3.65e-2)" BSDC1 "FLJ10276, RP4-811H24.7" ENSG00000160058 "BSD domain containing 1" Q9NW68 1 32364633-32394731 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 37.4" "Lineage enriched" "Detected in all" 4 "granulocytes: 37.4" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031358, HPA031360" Approved Supported "Golgi apparatus,Plasma membrane" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 37: Non-specific - mRNA processing" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 3 "Golgi apparatus" "Plasma membrane" "HPA031358: , HPA031360: " "unprognostic (5.57e-2)" "unprognostic (8.32e-2)" "unprognostic (2.18e-1)" "unprognostic (9.87e-2)" "unprognostic (3.29e-1)" "unprognostic (2.74e-1)" "unprognostic (2.41e-1)" "potential prognostic favorable (6.08e-7)" "unprognostic (2.66e-3)" "potential prognostic unfavorable (2.83e-4)" "potential prognostic favorable (9.41e-4)" "unprognostic (1.80e-3)" "unprognostic (2.23e-1)" "unprognostic (2.30e-1)" "unprognostic (1.79e-1)" "unprognostic (5.57e-3)" "unprognostic (2.96e-1)" "unprognostic (1.05e-2)" "unprognostic (3.73e-1)" "unprognostic (1.82e-1)" "unprognostic (3.49e-1)" "unprognostic (1.58e-2)" "unprognostic (4.35e-1)" "unprognostic (7.64e-2)" "unprognostic (8.28e-2)" "unprognostic (6.99e-3)" "unprognostic (1.97e-1)" "unprognostic (4.26e-2)" "unprognostic (6.69e-2)" "unprognostic (1.18e-2)" "unprognostic (9.41e-2)" BSG "CD147, EMMPRIN, EMPRIN, OK" ENSG00000172270 "Basigin (Ok blood group)" P35613 19 571277-583494 "Blood group antigen proteins, CD markers, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Angiogenesis, Host-virus interaction" "Blood group antigen, Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1787.2" "Cell type enhanced" "Detected in many" "Colonocytes: 1506.8;Cytotrophoblasts: 1735.5;Decidual stromal cells: 1468.2;Extravillous trophoblasts: 1432.2;Migrating cytotrophoblasts: 1316.3;Syncytiotrophoblasts: 1877.9" "Cell type enhanced" "Detected in all" "endothelial cell: 700.9;pericyte: 477.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Heart muscle - Cardiomyocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002427, HPA036048, HPA074870" Enhanced Approved "Vesicles,Mid piece,Principal piece,End piece" NA NA 360000 "Cluster 7: Non-specific - Innate immune response" "Cluster 52: Non-specific - Cellular respiration" "Cluster 23: Choroid plexus - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 104 Vesicles "Mid piece, Principal piece, End piece" "CAB002427: , HPA036048: , HPA074870: " "unprognostic (2.38e-1)" "unprognostic (4.10e-2)" "unprognostic (2.74e-1)" "unprognostic (3.83e-1)" "unprognostic (3.85e-3)" "unprognostic (6.30e-2)" "unprognostic (1.27e-1)" "unprognostic (3.25e-1)" "unprognostic (1.57e-2)" "unprognostic (7.39e-2)" "potential prognostic favorable (6.16e-4)" "unprognostic (7.22e-2)" "potential prognostic favorable (3.62e-5)" "validated prognostic unfavorable (2.30e-6)" "validated prognostic unfavorable (8.85e-5)" "potential prognostic unfavorable (3.20e-4)" "unprognostic (1.58e-1)" "unprognostic (1.16e-1)" "unprognostic (2.49e-1)" "unprognostic (1.07e-1)" "unprognostic (1.88e-1)" "unprognostic (2.48e-2)" "unprognostic (2.75e-1)" "unprognostic (3.80e-2)" "unprognostic (5.99e-2)" "unprognostic (1.23e-1)" "unprognostic (3.87e-1)" "unprognostic (1.28e-1)" "unprognostic (1.98e-1)" "unprognostic (1.45e-1)" "unprognostic (4.42e-2)" BSN ZNF231 ENSG00000164061 "Bassoon presynaptic cytomatrix protein" Q9UPA5 3 49554477-49671549 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 29.1" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 42.5;Brain excitatory neurons: 100.7;Brain inhibitory neurons: 74.4;Corticotrophs: 52.3;Gonadotrophs: 46.7;Lactotrophs: 68.0;Other brain neurons: 57.0;Retinal amacrine cells: 71.9;Retinal bipolar cells: 39.0;Retinal horizontal cells: 58.1;Rod photoreceptor cells: 35.0;Somatotrophs: 56.1;Thyrotrophs: 67.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 2.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 6.7" "Colon - Colon enteroendocrine cells, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034757 Enhanced NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" 1 "HPA034757: " "unprognostic (1.09e-1)" "unprognostic (1.86e-1)" "unprognostic (8.36e-2)" "unprognostic (2.23e-1)" BSND "BART, DFNB73" ENSG00000162399 "Barttin CLCNK type accessory subunit beta" Q8WZ55 1 54998933-55017172 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Bartter syndrome, Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "kidney: 3.8;salivary gland: 1.4" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 10.2;Epicardial cells: 11.4;Epididymal clear cells: 38.8;Loop of henle epithelial cells: 14.6;Renal collecting duct intercalated cells: 20.7;Respiratory ionocytes: 111.8;Salivary ionocytes: 69.5" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 32 "Kidney Chromophobe (TCGA): 20.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Minor Salivary Gland - Minor salivary gland ductal cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA053836, HPA060617" Enhanced NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 44 "HPA053836: , HPA060617: " "unprognostic (1.46e-2)" BSPH1 "BSP1, ELSPBP2" ENSG00000188334 "Binder of sperm protein homolog 1" Q075Z2 19 47968046-47992170 "Predicted intracellular proteins, Predicted secreted proteins" Fertilization "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 52 "epididymis: 361.3" "Cell type enriched" "Detected in some" 16 "Epididymal principal cells: 272.6" "Cell type enriched" "Detected in some" 11 "cerebellar inhibitory: 13.0" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 1.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA048335 Enhanced "Secreted in male reproductive system" Other NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 2: Neurons - Nucleosome" "Cluster 38: Non-specific - Transcription" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" "HPA048335: " BSPRY FLJ20150 ENSG00000119411 "B-box and SPRY domain containing" Q5W0U4 9 113349541-113371233 "Predicted intracellular proteins" "Calcium transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "parathyroid gland: 420.6" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 85.7;Breast lactating cells: 174.4;Esophageal apical cells: 260.1;Esophageal suprabasal cells: 155.3;Salivary acinar cells: 152.1" "Cell type enhanced" "Detected in many" "eccentric medium spiny neuron: 16.4;medium spiny neuron: 29.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 21 "plasmacytoid DC: 4.4" "Lineage enriched" "Detected in single" 21 "dendritic cells: 4.4" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Mast cells, Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Breast - Breast glandular cells, Liver - Cholangiocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "Region enriched" "Detected in single" 6 "cerebellum: 4.8" "HPA042889, HPA077485" Approved Uncertain Nucleoplasm,Cytosol NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 33: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 4 Nucleoplasm Cytosol "HPA042889: , HPA077485: " "unprognostic (1.33e-2)" "unprognostic (2.44e-2)" "unprognostic (2.25e-1)" "unprognostic (7.79e-3)" "unprognostic (1.65e-1)" "unprognostic (5.71e-2)" "unprognostic (7.38e-3)" "unprognostic (1.43e-1)" "validated prognostic favorable (1.34e-9)" "validated prognostic favorable (1.55e-4)" "unprognostic (2.80e-2)" "unprognostic (1.22e-1)" "unprognostic (2.65e-1)" "unprognostic (3.17e-1)" "unprognostic (2.07e-1)" "potential prognostic unfavorable (9.45e-4)" "unprognostic (8.00e-2)" "unprognostic (2.29e-1)" "unprognostic (3.42e-1)" "unprognostic (2.07e-1)" "unprognostic (5.86e-2)" "unprognostic (9.18e-3)" "unprognostic (4.90e-2)" "unprognostic (2.50e-2)" "unprognostic (2.39e-1)" "unprognostic (7.59e-3)" "unprognostic (5.94e-1)" "unprognostic (1.29e-1)" "unprognostic (2.37e-2)" BST1 "BST-1, cADPR2, CD157" ENSG00000109743 "Bone marrow stromal cell antigen 1" Q10588 4 15703065-15738313 "CD markers, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 131.9;intestine: 45.7" "Cell type enhanced" "Detected in many" "Enterocytes: 75.9;Monocyte progenitors: 55.7;monocytes: 73.4;Neutrophil progenitors: 224.7;Neutrophils: 223.6" "Cell type enhanced" "Detected in some" "fibroblast: 14.5;pericyte: 19.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 258.3;neutrophil: 294.2" "Group enriched" "Detected in many" 94 "dendritic cells: 79.0;granulocytes: 294.2;monocytes: 258.3" "Low cancer specificity" "Detected in many" "Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Spleen - Neutrophils_2, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA050121 Uncertain "Intracellular and membrane" Enzyme NA NA 52000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 15: Bone marrow - Innate immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 48: Neutrophils - Phagocytosis & degranulation" "HPA050121: " "unprognostic (7.12e-2)" "unprognostic (2.33e-1)" "unprognostic (2.13e-1)" "unprognostic (1.19e-2)" "unprognostic (1.10e-1)" "unprognostic (8.33e-2)" "unprognostic (2.95e-2)" "unprognostic (1.43e-1)" "unprognostic (2.82e-1)" "unprognostic (3.55e-2)" "potential prognostic favorable (1.66e-5)" "unprognostic (4.49e-3)" "unprognostic (1.55e-1)" "unprognostic (3.83e-1)" "unprognostic (6.64e-2)" "unprognostic (3.46e-2)" "unprognostic (1.24e-1)" "unprognostic (5.35e-2)" "unprognostic (4.75e-1)" "unprognostic (2.09e-1)" "unprognostic (4.43e-1)" "unprognostic (6.22e-2)" "unprognostic (2.92e-1)" "unprognostic (7.84e-3)" "unprognostic (3.98e-2)" "unprognostic (2.54e-1)" "unprognostic (1.67e-2)" "potential prognostic unfavorable (2.62e-4)" "unprognostic (2.83e-1)" "unprognostic (4.08e-2)" "unprognostic (1.84e-2)" BST2 "BST-2, CD317, HM1.24, tetherin" ENSG00000130303 "Bone marrow stromal cell antigen 2" Q10589 19 17402939-17405630 "CD markers, Plasma proteins, Predicted membrane proteins, Transporters" "Antiviral defense, B-cell activation, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 500.9;ovary: 677.0" "Cell type enhanced" "Detected in many" "Breast lactating cells: 260.9;Endometrial secretory cells: 261.2;Granulosa cells: 403.1;Hematopoietic stem cells: 307.6;Hofbauer cells: 528.3;Mast cells: 277.2;Medullary thymic epithelial cells: 309.6;Ovarian stromal cells: 1148.5;Peritubular myoid cells: 349.1;Vascular endothelial cells: 337.4" "Cell type enhanced" "Detected in some" "endothelial cell: 258.9;fibroblast: 79.5;leukocyte: 71.9;pericyte: 71.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017060, HPA073472" Enhanced Supported "Golgi apparatus,Vesicles" NA NA 140000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 75: Ovary - Mixed function" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 94: Gonadal somatic cells - Mixed function" 4 "Golgi apparatus, Vesicles" "HPA017060: , HPA073472: " "unprognostic (1.71e-1)" "unprognostic (1.51e-3)" "unprognostic (8.32e-2)" "unprognostic (6.25e-2)" "unprognostic (2.09e-2)" "unprognostic (2.79e-1)" "unprognostic (7.90e-2)" "unprognostic (3.17e-2)" "unprognostic (4.55e-1)" "unprognostic (3.71e-2)" "unprognostic (3.13e-2)" "unprognostic (9.59e-3)" "unprognostic (1.37e-3)" "unprognostic (1.72e-1)" "unprognostic (8.03e-2)" "unprognostic (7.26e-2)" "unprognostic (6.94e-2)" "unprognostic (1.35e-1)" "unprognostic (2.25e-2)" "unprognostic (3.39e-1)" "unprognostic (4.31e-1)" "unprognostic (1.26e-3)" "unprognostic (4.09e-3)" "unprognostic (2.78e-1)" "unprognostic (1.72e-1)" "unprognostic (1.02e-1)" "unprognostic (4.34e-1)" "unprognostic (6.25e-2)" "potential prognostic unfavorable (6.45e-4)" "unprognostic (1.33e-1)" "unprognostic (2.94e-1)" BSX BSX1 ENSG00000188909 "Brain specific homeobox" Q3C1V8 11 122977570-122981834 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Foveolar cells: 1.0;Other brain neurons: 1.7;pDCs: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in some" 7 "hypothalamus: 24.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in single" 5 "hypothalamus: 4.5" "Region enriched" "Detected in single" 10 "hypothalamus: 4.4" HPA015654 Uncertain NA NA "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 98: Neurons - Neurotransmission & signaling" "HPA015654: " BTAF1 "MOT1, TAF-172, TAF(II)170, TAF172, TAFII170" ENSG00000095564 "B-TFIID TATA-box binding protein associated factor 1" O14981 10 91923770-92031437 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070682 Supported Nucleoplasm,Vesicles NA NA "Cluster 32: Basophils - Transcription" "Cluster 58: Skin - Keratinization" "Cluster 55: Non-specific - Transcription" "Cluster 56: Non-specific - Sensory perception" "Cluster 103: Non-specific - Basic cellular processes" 21 Nucleoplasm Vesicles "HPA070682: " "unprognostic (4.53e-2)" "unprognostic (8.44e-2)" "unprognostic (3.46e-1)" "unprognostic (2.01e-1)" "unprognostic (1.63e-1)" "unprognostic (1.44e-1)" "unprognostic (2.53e-1)" "potential prognostic favorable (1.41e-4)" "unprognostic (3.68e-2)" "unprognostic (9.29e-2)" "unprognostic (4.81e-2)" "unprognostic (1.16e-1)" "unprognostic (7.65e-2)" "unprognostic (1.34e-1)" "unprognostic (2.33e-1)" "unprognostic (3.22e-1)" "unprognostic (1.73e-1)" "unprognostic (2.56e-2)" "unprognostic (1.18e-2)" "unprognostic (2.43e-2)" "unprognostic (1.44e-1)" "unprognostic (1.31e-1)" "unprognostic (1.23e-3)" "unprognostic (7.36e-2)" "unprognostic (1.33e-3)" "unprognostic (2.13e-3)" "unprognostic (1.43e-1)" "unprognostic (1.35e-1)" "unprognostic (1.96e-1)" "unprognostic (4.76e-2)" "unprognostic (9.18e-2)" BTBD1 ENSG00000064726 "BTB domain containing 1" Q9H0C5 15 83016423-83067252 "Predicted intracellular proteins" "Differentiation, Myogenesis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 304.4;tongue: 215.5" "Cell type enhanced" "Detected in many" "Myonuclei: 221.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Endothelial cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024263, HPA067671" Enhanced Supported "Nucleoplasm,Cytosol,Cytoplasmic bodies" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 27: Non-specific - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 100: Stratified epithelial cells - Barrier functions" 59 "Cytoplasmic bodies" "Nucleoplasm, Cytosol" "HPA024263: , HPA067671: " "unprognostic (1.42e-2)" "unprognostic (3.54e-1)" "unprognostic (1.41e-1)" "unprognostic (1.02e-1)" "unprognostic (1.24e-1)" "unprognostic (6.75e-2)" "unprognostic (4.59e-2)" "unprognostic (2.33e-1)" "unprognostic (1.36e-2)" "potential prognostic unfavorable (8.86e-4)" "potential prognostic favorable (5.66e-7)" "unprognostic (6.14e-2)" "unprognostic (2.75e-1)" "unprognostic (2.47e-2)" "unprognostic (4.85e-3)" "unprognostic (1.13e-2)" "unprognostic (1.11e-2)" "unprognostic (1.07e-1)" "unprognostic (2.55e-1)" "unprognostic (4.94e-2)" "unprognostic (6.62e-2)" "unprognostic (3.08e-1)" "unprognostic (3.80e-1)" "unprognostic (1.16e-1)" "unprognostic (5.63e-2)" "unprognostic (9.87e-3)" "unprognostic (7.83e-2)" "unprognostic (3.05e-2)" "unprognostic (2.12e-1)" "unprognostic (2.33e-1)" "unprognostic (2.81e-1)" BTBD10 "GMRP-1, GMRP1, MGC13007" ENSG00000148925 "BTB domain containing 10" Q9BSF8 11 13388008-13463297 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046777 Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Plasma membrane" NA Yes "Cluster 42: Non-specific - Vesicular transport" "Cluster 73: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 24: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 5 "Nucleoli fibrillar center" "Nucleoplasm, Plasma membrane" "HPA046777: " "unprognostic (9.12e-2)" "unprognostic (7.28e-2)" "unprognostic (1.51e-1)" "unprognostic (1.46e-1)" "unprognostic (2.13e-1)" "unprognostic (2.26e-1)" "unprognostic (4.28e-2)" "unprognostic (3.79e-2)" "unprognostic (5.06e-2)" "unprognostic (2.53e-2)" "potential prognostic favorable (8.26e-6)" "unprognostic (8.97e-3)" "unprognostic (3.14e-1)" "potential prognostic unfavorable (5.43e-4)" "unprognostic (3.21e-1)" "unprognostic (7.85e-2)" "unprognostic (4.14e-2)" "unprognostic (1.44e-1)" "unprognostic (4.78e-2)" "unprognostic (1.13e-1)" "unprognostic (1.52e-3)" "unprognostic (2.29e-3)" "unprognostic (9.13e-3)" "unprognostic (1.93e-1)" "unprognostic (6.43e-2)" "unprognostic (1.61e-1)" "unprognostic (1.87e-1)" "unprognostic (2.25e-1)" "unprognostic (2.66e-1)" "unprognostic (2.42e-1)" "unprognostic (1.94e-1)" BTBD16 "C10orf87, Em:AC061711.1, FLJ25359" ENSG00000138152 "BTB domain containing 16" Q32M84 10 122271296-122338159 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skin 1: 7.9;testis: 7.3;urinary bladder: 18.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 54.9;Early spermatids: 118.9;Late primary spermatocytes: 87.8;Late spermatids: 86.3;Papillary tip epithelial cells: 29.4;Urothelial cells: 255.7" "Cell type enhanced" "Detected in many" "oligodendrocyte: 16.7" "Cancer enriched" "Detected in some" 8 "Bladder Urothelial Carcinoma (TCGA): 15.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 4.2;pancreatic cancer: 5.1" "Skin - Keratinocyte (granular), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA040529, HPA057638" Uncertain Uncertain Nucleoli,Cytosol Yes NA "Cluster 47: Testis - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 69: Urothelial cells - Basic cellular functions" Nucleoli Cytosol "HPA040529: , HPA057638: " "unprognostic (2.07e-1)" "unprognostic (4.37e-1)" "unprognostic (1.39e-1)" "unprognostic (3.35e-3)" "unprognostic (4.20e-1)" "unprognostic (1.33e-1)" "unprognostic (1.58e-2)" "unprognostic (1.13e-1)" "unprognostic (6.64e-2)" BTBD17 "BTBD17A, LGALS3BPL, TANGO10A" ENSG00000204347 "BTB domain containing 17" A6NE02 17 74356416-74361868 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 14 "brain: 7.1" "Cell type enhanced" "Detected in some" "Astrocytes: 9.6;Bergmann glia: 28.9;Ependymal cells: 5.4;Late spermatids: 6.4;Neuroendocrine cells: 6.1;Oligodendrocyte progenitor cells: 9.8;Pancreatic islet cells: 7.5;Retinal horizontal cells: 8.0;Sertoli cells: 5.9" "Cell type enhanced" "Detected in some" "astrocyte: 11.5;Bergmann glia: 30.9;oligodendrocyte precursor cell: 11.7" "Cancer enriched" "Detected in some" 5 "Glioblastoma Multiforme (TCGA): 15.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bone cancer: 10.9;lung cancer: 4.0" "Adrenal gland - Adrenal medulla cells, Pancreas - Alpha cells, Pituitary gland - Undifferentiated cells (Pituitary gland)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA025022, HPA063875" Approved Approved Cytosol "Secreted in brain" "No annotated function" NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" Cytosol "HPA025022: , HPA063875: " "unprognostic (9.20e-2)" "unprognostic (6.15e-2)" "unprognostic (3.07e-1)" BTBD18 ENSG00000233436 "BTB domain containing 18" B2RXH4 11 57743514-57752675 "Predicted intracellular proteins" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 8 "testis: 2.1" "Cell type enhanced" "Detected in many" "Adipocytes: 16.2;Cardiomyocytes: 46.6;Epicardial cells: 70.5;Medullary thymic epithelial cells: 12.0;Myonuclei: 17.5" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA049325 Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 47: Testis - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 1 "Nucleoplasm, Plasma membrane" Vesicles "HPA049325: " "unprognostic (7.90e-3)" "unprognostic (8.57e-2)" BTBD19 ENSG00000222009 "BTB domain containing 19" C9JJ37 1 44808523-44815585 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Neutrophils: 200.4" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 30.7;fibroblast: 19.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA042633, HPA076404" Uncertain Uncertain Cytosol NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 12: Non-specific - Vasculature" "Cluster 56: Non-specific - Sensory perception" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" Cytosol "HPA042633: , HPA076404: " "unprognostic (1.24e-2)" "unprognostic (3.78e-2)" "unprognostic (3.45e-2)" "unprognostic (2.35e-1)" "unprognostic (1.16e-2)" "unprognostic (4.50e-1)" "unprognostic (7.62e-2)" "unprognostic (5.30e-2)" "unprognostic (1.11e-1)" "unprognostic (1.27e-2)" "unprognostic (7.49e-3)" "unprognostic (6.48e-3)" BTBD2 ENSG00000133243 "BTB domain containing 2" Q9BX70 19 1985438-2034881 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 159.5" "Cell type enhanced" "Detected in many" "Epicardial cells: 125.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 18: Non-specific - Translation" "Cluster 78: Brain - Neuronal signaling" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 20: Non-specific - Transcription regulation" 35 "unprognostic (4.71e-1)" "unprognostic (7.07e-2)" "unprognostic (1.42e-2)" "unprognostic (4.48e-2)" "unprognostic (3.89e-2)" "unprognostic (1.98e-1)" "unprognostic (1.71e-1)" "unprognostic (2.78e-2)" "unprognostic (5.18e-2)" "unprognostic (4.10e-2)" "potential prognostic favorable (8.64e-6)" "unprognostic (2.67e-2)" "unprognostic (1.15e-1)" "validated prognostic unfavorable (7.48e-5)" "validated prognostic unfavorable (3.93e-4)" "unprognostic (2.62e-2)" "potential prognostic unfavorable (2.07e-4)" "unprognostic (1.25e-1)" "unprognostic (1.10e-1)" "unprognostic (1.15e-1)" "unprognostic (2.62e-2)" "unprognostic (4.52e-1)" "unprognostic (1.13e-1)" "unprognostic (3.39e-2)" "unprognostic (1.98e-3)" "unprognostic (6.44e-2)" "unprognostic (2.36e-1)" "unprognostic (2.53e-2)" "unprognostic (1.32e-1)" "unprognostic (3.83e-1)" "unprognostic (1.37e-1)" BTBD3 "dJ742J24.1, KIAA0952" ENSG00000132640 "BTB domain containing 3" Q9Y2F9 20 11890723-11926609 "Predicted intracellular proteins" Neurogenesis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 65.8" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 199.9;Endometrial stromal cells: 240.4;Oligodendrocytes: 243.9;Parietal cells: 256.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 3.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Liver - Vascular endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041424, HPA042048" Uncertain Supported Vesicles NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 27: Cerebellum - Synaptic function" "Cluster 34: Non-specific - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 51: Secretory epithelial cells - Mixed function" 9 Vesicles "HPA041424: , HPA042048: " "unprognostic (1.36e-3)" "unprognostic (3.61e-2)" "unprognostic (1.45e-1)" "unprognostic (4.24e-2)" "unprognostic (1.79e-1)" "potential prognostic unfavorable (9.61e-4)" "unprognostic (2.36e-2)" "unprognostic (3.51e-3)" "unprognostic (8.60e-2)" "unprognostic (4.50e-2)" "validated prognostic favorable (1.03e-6)" "validated prognostic favorable (3.34e-4)" "unprognostic (2.42e-1)" "potential prognostic unfavorable (6.94e-5)" "unprognostic (1.23e-2)" "unprognostic (3.18e-2)" "unprognostic (1.41e-3)" "unprognostic (3.43e-2)" "unprognostic (3.28e-1)" "unprognostic (1.34e-1)" "unprognostic (3.25e-2)" "unprognostic (4.82e-2)" "unprognostic (1.65e-1)" "unprognostic (2.23e-1)" "unprognostic (7.80e-2)" "unprognostic (2.04e-1)" "unprognostic (1.55e-1)" "unprognostic (1.07e-2)" "unprognostic (2.01e-1)" "unprognostic (9.68e-2)" "unprognostic (2.18e-1)" BTBD6 BDPL ENSG00000184887 "BTB domain containing 6" Q96KE9 14 105248533-105251093 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Megakaryocytes: 204.0;Platelets: 102.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031355 Approved Approved Nucleoplasm NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 51: Neurons - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 47: Platelets - Hemostasis" 5 Nucleoplasm "HPA031355: " "unprognostic (3.48e-3)" "unprognostic (1.01e-2)" "unprognostic (2.68e-2)" "unprognostic (8.47e-2)" "unprognostic (2.53e-1)" "unprognostic (8.66e-2)" "unprognostic (1.86e-1)" "unprognostic (1.84e-1)" "unprognostic (1.15e-1)" "unprognostic (3.73e-2)" "potential prognostic favorable (1.12e-4)" "unprognostic (6.80e-2)" "unprognostic (3.61e-3)" "unprognostic (3.72e-2)" "unprognostic (7.89e-2)" "unprognostic (2.08e-1)" "unprognostic (2.74e-1)" "unprognostic (2.56e-1)" "unprognostic (2.05e-1)" "unprognostic (2.49e-1)" "unprognostic (3.40e-2)" "potential prognostic favorable (5.06e-4)" "unprognostic (1.93e-1)" "unprognostic (1.30e-2)" "unprognostic (3.28e-1)" "unprognostic (2.94e-1)" "unprognostic (2.51e-1)" "unprognostic (8.33e-2)" "unprognostic (1.37e-1)" "unprognostic (2.73e-1)" "unprognostic (2.84e-1)" BTBD7 "FLJ10648, FUP1" ENSG00000011114 "BTB domain containing 7" Q9P203 14 93237550-93333092 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 142.5;Bergmann glia: 278.6;Brain excitatory neurons: 102.4;Brain inhibitory neurons: 115.0;Choroid plexus epithelial cells: 141.7;Distal convoluted tubule cells: 194.6;Loop of henle epithelial cells: 181.4;Microglia: 231.6;Oligodendrocyte progenitor cells: 121.3;Oligodendrocytes: 204.7;Other brain neurons: 105.5;Papillary tip epithelial cells: 134.8;Podocytes: 120.5;Proximal tubule cells: 211.6;Renal collecting duct intercalated cells: 160.0;Renal collecting duct principal cells: 172.7;Renal connecting tubule cells: 268.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049926, HPA053406" Uncertain Approved "Focal adhesion sites" NA NA "Cluster 32: Basophils - Transcription" "Cluster 47: Testis - Mixed function" "Cluster 25: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 102: Non-specific - Mixed function" 1 "Focal adhesion sites" "HPA049926: , HPA053406: " "unprognostic (4.52e-1)" "unprognostic (1.11e-1)" "unprognostic (8.60e-2)" "unprognostic (7.66e-3)" "unprognostic (6.67e-2)" "unprognostic (1.08e-1)" "unprognostic (4.02e-3)" "unprognostic (1.18e-1)" "unprognostic (4.61e-3)" "validated prognostic favorable (4.40e-7)" "validated prognostic favorable (1.18e-5)" "unprognostic (2.17e-1)" "unprognostic (2.41e-1)" "unprognostic (1.39e-1)" "unprognostic (4.11e-2)" "unprognostic (2.85e-2)" "unprognostic (1.72e-1)" "unprognostic (8.17e-2)" "unprognostic (1.26e-3)" "unprognostic (2.02e-3)" "unprognostic (3.06e-3)" "unprognostic (1.17e-2)" "unprognostic (7.87e-2)" "unprognostic (1.24e-1)" "unprognostic (9.41e-2)" "unprognostic (8.82e-2)" "unprognostic (3.30e-1)" "unprognostic (2.30e-2)" "unprognostic (2.33e-2)" BTBD8 "APache, KIAA1107" ENSG00000189195 "BTB domain containing 8" "Q5XKL5, Q9UPP5" 1 92080305-92184725 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 12.6;retina: 16.7;testis: 4.8" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 140.8;Retinal amacrine cells: 197.0;Retinal bipolar cells: 212.0;Somatotrophs: 119.8" "Cell type enhanced" "Detected in all" "LAMP5-LHX6 and Chandelier: 476.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 10 "Gallbladder cancer: 10.5" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024216, HPA035311" Enhanced Supported Nucleoplasm NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 1 Nucleoplasm "HPA024216: , HPA035311: " "unprognostic (2.85e-1)" "unprognostic (2.47e-1)" "unprognostic (2.33e-2)" "unprognostic (2.36e-1)" "potential prognostic favorable (2.42e-5)" "unprognostic (4.44e-2)" "unprognostic (1.28e-1)" "unprognostic (1.80e-1)" "unprognostic (2.49e-1)" "unprognostic (1.69e-1)" BTBD9 "dJ322I12.1, KIAA1880" ENSG00000183826 "BTB domain containing 9" Q96Q07 6 38168451-38640148 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Skin - Keratinocyte (granular), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041930 Uncertain Approved Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 35: Neurons - Synaptic function & neurogenesis" 8 Nucleoplasm "HPA041930: " "unprognostic (2.83e-2)" "unprognostic (5.80e-2)" "unprognostic (1.11e-1)" "unprognostic (5.40e-2)" "unprognostic (1.10e-3)" "unprognostic (2.20e-2)" "unprognostic (5.73e-2)" "unprognostic (4.56e-2)" "unprognostic (7.89e-3)" "unprognostic (1.98e-1)" "potential prognostic favorable (2.27e-5)" "unprognostic (6.16e-3)" "potential prognostic favorable (2.56e-4)" "unprognostic (1.57e-2)" "unprognostic (3.47e-2)" "potential prognostic favorable (8.13e-4)" "unprognostic (4.88e-1)" "unprognostic (3.42e-2)" "unprognostic (3.32e-2)" "unprognostic (4.35e-2)" "unprognostic (2.50e-2)" "unprognostic (9.90e-2)" "unprognostic (1.42e-1)" "unprognostic (2.62e-1)" "unprognostic (2.59e-3)" "unprognostic (1.10e-1)" "unprognostic (3.69e-1)" "unprognostic (1.49e-1)" "unprognostic (1.59e-1)" "unprognostic (1.43e-1)" "unprognostic (1.14e-1)" BTC ENSG00000174808 Betacellulin P35070 4 74744759-74794523 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Growth factor, Mitogen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 24.8" "Cell type enhanced" "Detected in many" "Ependymal cells: 39.7;Epididymal efferent duct ciliated cells: 46.2;Podocytes: 52.7;Respiratory ciliated cells: 50.8;Retinal pigment epithelial cells: 76.7" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 45.8;ependymal cell: 43.6" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "choroid plexus: 8.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 16.7" "Pituitary gland - Undifferentiated cells (Pituitary gland), Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to blood" "Growth factor" NA NA 314000 "Cluster 11: Esophagus - Basic cellular processes" "Cluster 17: Choroid plexus - Cilium" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" 7 "unprognostic (1.68e-1)" "unprognostic (3.49e-2)" "unprognostic (1.03e-1)" "unprognostic (1.86e-1)" "unprognostic (1.67e-2)" "unprognostic (3.70e-2)" "unprognostic (1.71e-2)" "unprognostic (1.12e-1)" "unprognostic (5.02e-2)" "unprognostic (6.19e-3)" "unprognostic (3.91e-1)" "unprognostic (2.64e-1)" "unprognostic (4.90e-2)" "unprognostic (9.39e-2)" "unprognostic (3.71e-2)" "unprognostic (7.17e-2)" "unprognostic (1.67e-2)" "unprognostic (2.14e-1)" "unprognostic (2.92e-2)" "unprognostic (1.27e-1)" "unprognostic (3.10e-1)" "unprognostic (1.39e-3)" "unprognostic (2.27e-1)" "unprognostic (2.48e-1)" "unprognostic (3.31e-1)" "unprognostic (1.68e-1)" BTD ENSG00000169814 Biotinidase P43251 3 15601341-15722311 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 93.6" "Cell type enhanced" "Detected in all" "Adipocytes: 336.2;Epicardial cells: 359.3;Mast cells: 306.1;Plasma cells: 558.0;Rod photoreceptor cells: 414.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052275 Uncertain "Secreted to blood" Enzyme NA NA 2300000000 "Cluster 41: Basophils - Unknown function" "Cluster 22: Epididymis - Mixed function" "Cluster 55: Non-specific - Transcription" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 78: Plasma cells - Antibody production & ER-stress response" 1 "HPA052275: " "unprognostic (1.17e-2)" "unprognostic (2.19e-1)" "unprognostic (3.26e-1)" "unprognostic (8.09e-2)" "unprognostic (9.44e-2)" "unprognostic (2.30e-2)" "unprognostic (1.73e-1)" "unprognostic (7.44e-2)" "unprognostic (1.95e-1)" "unprognostic (3.28e-2)" "potential prognostic favorable (9.91e-8)" "unprognostic (8.48e-2)" "unprognostic (1.96e-2)" "unprognostic (1.94e-2)" "unprognostic (1.82e-2)" "unprognostic (1.23e-1)" "unprognostic (1.88e-1)" "potential prognostic unfavorable (5.26e-4)" "unprognostic (9.67e-3)" "unprognostic (6.08e-2)" "potential prognostic unfavorable (5.79e-4)" "unprognostic (9.07e-2)" "unprognostic (2.18e-2)" "unprognostic (4.02e-1)" "unprognostic (2.86e-3)" "unprognostic (1.51e-3)" "unprognostic (3.10e-1)" "unprognostic (1.08e-2)" "unprognostic (1.61e-1)" "unprognostic (2.97e-3)" "unprognostic (1.61e-1)" BTF3 "BTF3a, BTF3b, NACB" ENSG00000145741 "Basic transcription factor 3" P20290 5 73498408-73505667 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transcription, Transcription regulation, Transport" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 2547.7;Esophageal apical cells: 3272.4;Esophageal basal cells: 2528.0;Esophageal suprabasal cells: 2694.2;Extravillous trophoblasts: 2367.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013007, HPA056420, HPA074056" Approved Supported Cytosol NA Yes 130000 "Cluster 33: Non-specific - ATP binding" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 68 Cytosol "CAB013007: , HPA056420: , HPA074056: " "unprognostic (7.09e-2)" "unprognostic (3.56e-2)" "unprognostic (4.57e-2)" "unprognostic (4.99e-2)" "unprognostic (3.01e-1)" "unprognostic (3.55e-2)" "unprognostic (1.03e-1)" "unprognostic (2.36e-2)" "unprognostic (8.39e-3)" "potential prognostic unfavorable (4.98e-4)" "potential prognostic favorable (1.25e-4)" "unprognostic (2.14e-2)" "unprognostic (2.18e-2)" "validated prognostic unfavorable (5.43e-6)" "validated prognostic unfavorable (2.60e-4)" "unprognostic (5.51e-3)" "unprognostic (5.36e-3)" "unprognostic (1.38e-1)" "unprognostic (2.96e-2)" "unprognostic (1.17e-1)" "unprognostic (4.54e-2)" "unprognostic (2.65e-3)" "unprognostic (6.15e-2)" "unprognostic (3.03e-3)" "unprognostic (1.22e-2)" "unprognostic (4.13e-2)" "unprognostic (1.19e-3)" "unprognostic (3.87e-2)" "unprognostic (2.50e-1)" "unprognostic (1.60e-1)" "unprognostic (3.62e-2)" BTF3L4 MGC23908 ENSG00000134717 "Basic transcription factor 3 like 4" Q96K17 1 52056199-52090716 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067026, HPA074056" Approved Approved Nucleoplasm,Cytosol NA NA 23000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 97: Non-specific - Cellular respiration" 34 "Nucleoplasm, Cytosol" "HPA067026: , HPA074056: " "unprognostic (4.98e-2)" "unprognostic (1.16e-2)" "unprognostic (2.38e-3)" "unprognostic (5.51e-2)" "unprognostic (9.93e-2)" "unprognostic (3.87e-3)" "unprognostic (1.75e-2)" "unprognostic (1.21e-2)" "unprognostic (5.72e-3)" "unprognostic (3.55e-3)" "potential prognostic favorable (2.44e-4)" "unprognostic (1.72e-1)" "unprognostic (2.84e-2)" "validated prognostic unfavorable (1.28e-7)" "validated prognostic unfavorable (9.44e-5)" "unprognostic (3.94e-2)" "unprognostic (6.42e-2)" "unprognostic (3.28e-2)" "unprognostic (1.00e-1)" "unprognostic (1.10e-1)" "unprognostic (1.62e-1)" "unprognostic (6.83e-2)" "unprognostic (4.09e-2)" "unprognostic (2.68e-1)" "unprognostic (1.04e-1)" "unprognostic (3.07e-1)" "unprognostic (3.09e-1)" "unprognostic (1.83e-1)" "unprognostic (2.33e-1)" "unprognostic (5.80e-2)" "unprognostic (7.24e-3)" BTG1 APRO2 ENSG00000133639 "BTG anti-proliferation factor 1" P62324 12 92140278-92145846 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 88.7" "Cell type enhanced" "Detected in all" "B-cells: 2093.5;Basal keratinocytes: 1805.7;Innate lymphoid cells: 1944.9;Neutrophils: 2082.1;NK-cells: 1735.7;Ocular epithelial cells: 1586.9;Suprabasal keratinocytes: 1627.4;Syncytiotrophoblasts: 1705.8;T-cells: 2533.4" "Cell type enhanced" "Detected in all" "leukocyte: 329.1;pericyte: 231.5;upper rhombic lip: 249.1" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 74.3" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005972 Approved Nucleoplasm,Cytosol NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 35: Non-specific - DNA binding" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 16 Nucleoplasm Cytosol "HPA005972: " "unprognostic (1.43e-1)" "unprognostic (1.56e-2)" "unprognostic (2.41e-1)" "unprognostic (5.63e-3)" "unprognostic (1.83e-1)" "unprognostic (1.99e-2)" "unprognostic (1.01e-2)" "unprognostic (3.20e-2)" "unprognostic (8.96e-3)" "unprognostic (5.03e-3)" "potential prognostic favorable (9.25e-6)" "unprognostic (1.18e-2)" "unprognostic (3.63e-3)" "unprognostic (2.82e-1)" "unprognostic (4.66e-3)" "unprognostic (1.79e-1)" "unprognostic (6.97e-3)" "unprognostic (5.61e-2)" "unprognostic (4.94e-1)" "unprognostic (3.80e-1)" "unprognostic (8.65e-2)" "unprognostic (2.43e-1)" "unprognostic (1.81e-2)" "unprognostic (1.31e-1)" "unprognostic (2.74e-1)" "unprognostic (1.73e-2)" "unprognostic (2.30e-1)" "unprognostic (1.82e-1)" "unprognostic (4.49e-2)" "unprognostic (2.37e-3)" "unprognostic (2.65e-1)" BTG2 "APRO1, MGC126063, MGC126064, PC3, TIS21" ENSG00000159388 "BTG anti-proliferation factor 2" P78543 1 203305491-203309602 "Cancer-related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal basal cells: 1166.1;Neutrophils: 1236.6;Pancreatic acinar cells: 1186.2;Smooth muscle cells: 1231.6;Thymic myoid cells: 1220.9;Urothelial cells: 1394.3" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 173.2;endothelial cell: 171.5;vascular associated smooth muscle cell: 242.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "lymphoma: 137.9;Myeloma: 243.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 62.1" HPA002355 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 8: Pancreas - Proteolysis" "Cluster 25: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 11 Vesicles Nucleoplasm "HPA002355: " "potential prognostic favorable (5.99e-6)" "unprognostic (7.34e-3)" "unprognostic (3.17e-2)" "unprognostic (4.31e-1)" "unprognostic (8.29e-3)" "unprognostic (2.77e-1)" "unprognostic (2.60e-1)" "unprognostic (1.35e-3)" "unprognostic (2.77e-1)" "unprognostic (1.36e-1)" "potential prognostic favorable (6.26e-5)" "unprognostic (2.59e-3)" "unprognostic (1.31e-1)" "unprognostic (1.44e-1)" "unprognostic (1.61e-1)" "potential prognostic favorable (1.41e-4)" "unprognostic (2.89e-3)" "unprognostic (5.55e-2)" "unprognostic (2.39e-1)" "unprognostic (2.77e-1)" "unprognostic (1.17e-1)" "unprognostic (2.19e-1)" "unprognostic (5.46e-2)" "unprognostic (1.22e-3)" "unprognostic (2.21e-1)" "unprognostic (5.67e-2)" "unprognostic (4.35e-1)" "unprognostic (7.82e-2)" "unprognostic (1.61e-1)" "unprognostic (1.66e-1)" "unprognostic (2.10e-2)" BTG3 "ANA, ANA/BTG3, APRO4, tob55" ENSG00000154640 "BTG anti-proliferation factor 3" Q14201 21 17593653-17612945 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Syncytiotrophoblasts: 2124.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 31.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pituitary gland - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018400 Approved NA Yes "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 22: Epididymis - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 4: Non-specific - Transcription" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 3 "HPA018400: " "unprognostic (7.39e-2)" "unprognostic (9.47e-2)" "unprognostic (2.05e-1)" "unprognostic (3.37e-2)" "unprognostic (6.63e-2)" "unprognostic (1.41e-1)" "unprognostic (2.15e-1)" "unprognostic (3.52e-1)" "potential prognostic favorable (7.68e-4)" "unprognostic (8.04e-2)" "potential prognostic unfavorable (2.90e-4)" "unprognostic (1.29e-2)" "unprognostic (1.28e-1)" "potential prognostic unfavorable (3.59e-6)" "unprognostic (3.30e-3)" "unprognostic (1.34e-1)" "unprognostic (7.91e-3)" "unprognostic (1.52e-2)" "unprognostic (1.58e-1)" "unprognostic (1.36e-1)" "unprognostic (2.34e-2)" "unprognostic (1.89e-1)" "unprognostic (8.83e-2)" "unprognostic (1.49e-1)" "unprognostic (6.36e-2)" "unprognostic (1.51e-2)" "unprognostic (2.19e-1)" "unprognostic (3.94e-2)" "unprognostic (2.75e-1)" "unprognostic (1.34e-1)" "unprognostic (3.65e-1)" BTG4 "APRO3, PC3B" ENSG00000137707 "BTG anti-proliferation factor 4" Q9NY30 11 111467526-111514367 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 21.2" "Cell type enhanced" "Detected in some" "Early primary spermatocytes: 33.5;Early spermatids: 115.4;Ependymal cells: 30.9;Late primary spermatocytes: 146.5;Late spermatids: 280.3;Respiratory ciliated cells: 54.9" "Group enriched" "Detected in some" 15 "choroid plexus epithelial cell: 17.4;ependymal cell: 38.4" "Not detected" "Not detected" "Region enriched" "Detected in some" 5 "choroid plexus: 10.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA057157 Approved "Endoplasmic reticulum,Golgi apparatus" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" 1 "Endoplasmic reticulum, Golgi apparatus" "HPA057157: " BTK "AGMX1, ATK, IMD1, PSCTK1, XLA" ENSG00000010671 "Bruton tyrosine kinase" Q06187 X 101349338-101390796 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Apoptosis, Immunity, Innate immunity, Transcription, Transcription regulation" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 24.2;lymphoid tissue: 62.7" "Cell type enhanced" "Detected in many" "B-cells: 81.0;cDC: 73.7;Hofbauer cells: 75.2;Kupffer cells: 64.6;Macrophages: 66.5;Mast cells: 158.0;Megakaryocyte progenitors: 89.9;Megakaryocyte-Erythroid progenitors: 61.8;Megakaryocytes: 309.1;Microglia: 60.1;monocytes: 73.9;Neutrophil progenitors: 54.0;Neutrophils: 77.9;pDCs: 79.8;Plasma cells: 60.7;Platelets: 272.5" "Cell type enriched" "Detected in some" 4 "central nervous system macrophage: 76.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 4 "basophil: 515.1" "Lineage enriched" "Detected in many" 4 "granulocytes: 515.1" "Group enriched" "Detected in some" 93 "Leukemia: 79.9;lymphoma: 84.3;Myeloma: 21.2" "Adipose subcutaneous - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Liver - Kupffer cells, Skeletal muscle - Macrophages, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA001198, HPA002028, CAB016689, CAB080300" Enhanced Supported "Plasma membrane,Cytosol" NA NA 1400000 "Cluster 32: Basophils - Transcription" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 58: Mast cells - Allergic inflammatory responses" 41 "Plasma membrane, Cytosol" "CAB016689: , CAB080300: , HPA001198: , HPA002028: " "unprognostic (2.58e-1)" "unprognostic (3.91e-2)" "unprognostic (2.72e-1)" "potential prognostic favorable (3.57e-4)" "unprognostic (9.42e-2)" "unprognostic (1.68e-1)" "unprognostic (2.52e-2)" "unprognostic (6.50e-2)" "unprognostic (1.15e-2)" "unprognostic (5.15e-2)" "unprognostic (8.47e-2)" "unprognostic (1.57e-1)" "unprognostic (1.07e-1)" "unprognostic (1.28e-1)" "unprognostic (1.20e-1)" "potential prognostic favorable (1.03e-5)" "unprognostic (3.35e-2)" "unprognostic (1.21e-1)" "unprognostic (2.83e-1)" "unprognostic (3.52e-1)" "unprognostic (4.26e-1)" "unprognostic (1.33e-1)" "unprognostic (2.66e-3)" "unprognostic (2.23e-1)" "unprognostic (2.12e-2)" "unprognostic (1.36e-1)" "unprognostic (3.19e-2)" "unprognostic (1.20e-1)" "unprognostic (4.51e-3)" "unprognostic (4.04e-2)" "unprognostic (9.55e-2)" BTLA "BTLA1, CD272" ENSG00000186265 "B and T lymphocyte associated" Q7Z6A9 3 112463966-112499472 "CD markers, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "lymphoid tissue: 26.8" "Cell type enhanced" "Detected in some" "B-cells: 121.1;cDC: 27.7;pDCs: 30.0;Plasma cells: 32.6;T-cells: 15.5;Thymocytes: 10.2" "Cell type enriched" "Detected in some" 13 "leukocyte: 16.7" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 2.8" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 5 "memory B-cell: 65.3;naive B-cell: 96.8;plasmacytoid DC: 24.9" "Group enriched" "Detected in many" 4 "B-cells: 96.8;dendritic cells: 24.9" "Cancer enhanced" "Detected in some" "lymphoma: 3.6;Myeloma: 13.3" "Breast - Plasma cells, Minor Salivary Gland - Plasma cells, Spleen - B-cells (Spleen)" "Not detected" "Not detected" "HPA047211, HPA062029, CAB080456" Enhanced "Secreted to blood" Receptor NA NA "Cluster 34: B-cells - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 37: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" "CAB080456: , HPA047211: , HPA062029: " "unprognostic (4.45e-2)" "unprognostic (5.62e-2)" "unprognostic (4.33e-2)" "potential prognostic favorable (4.16e-4)" "unprognostic (6.56e-2)" "unprognostic (1.96e-1)" "unprognostic (1.25e-1)" "unprognostic (1.69e-2)" "unprognostic (2.91e-2)" "unprognostic (4.08e-2)" BTN1A1 "BT, BTN, BTN1" ENSG00000124557 "Butyrophilin subfamily 1 member A1" Q13410 6 26500303-26510425 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 39 "breast: 29.8" "Cell type enriched" "Detected in some" 397 "Breast lactating cells: 1363.3" "Cell type enhanced" "Detected in single" "midbrain-derived inhibitory: 3.1" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "memory B-cell: 2.2;naive B-cell: 1.9" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Minor Salivary Gland - Plasma cells, Spleen - Mitotic cells (Spleen)" "Not detected" "Not detected" "Not detected" "Not detected" "HPA011126, CAB037340" Supported "Intracellular and membrane" "No annotated function" NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 55: Breast - Lactation" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 4: Breast lactating luminal cells - Lactation" 1 "CAB037340: , HPA011126: " BTN2A1 "BT2.1, BTF1, BTN2.1" ENSG00000112763 "Butyrophilin subfamily 2 member A1" Q7KYR7 6 26457904-26476621 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 86.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA019208 Approved Approved "Plasma membrane" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 2 "Plasma membrane" "HPA019208: " "unprognostic (8.98e-2)" "unprognostic (1.72e-2)" "unprognostic (7.77e-3)" "unprognostic (3.46e-2)" "unprognostic (1.73e-1)" "unprognostic (2.12e-2)" "unprognostic (7.85e-2)" "unprognostic (7.98e-2)" "unprognostic (6.86e-2)" "unprognostic (5.51e-2)" "potential prognostic favorable (2.97e-4)" "unprognostic (1.72e-3)" "unprognostic (1.46e-1)" "unprognostic (3.39e-3)" "unprognostic (1.94e-1)" "unprognostic (3.27e-2)" "unprognostic (2.18e-2)" "unprognostic (2.55e-1)" "unprognostic (3.21e-1)" "unprognostic (7.48e-2)" "unprognostic (5.28e-2)" "unprognostic (1.38e-1)" "unprognostic (6.24e-3)" "unprognostic (2.04e-1)" "unprognostic (2.34e-2)" "unprognostic (1.89e-1)" "unprognostic (4.66e-2)" "unprognostic (9.36e-2)" "unprognostic (2.18e-1)" "unprognostic (2.95e-2)" "unprognostic (7.10e-2)" BTN2A2 "BT2.2, BTF2, BTN2.2" ENSG00000124508 "Butyrophilin subfamily 2 member A2" Q8WVV5 6 26383096-26394874 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 32.6;cDC: 44.2;Mast cells: 58.4;Plasma cells: 44.0" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 20.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Myeloma: 76.2" "Prostate - T-cells, Spleen - B-cells (Spleen), Thyroid gland - T-cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA051504 Uncertain Approved Mitochondria NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 82: Dendritic cells - Antigen presentation" 34 Mitochondria "HPA051504: " "unprognostic (2.07e-2)" "unprognostic (1.10e-2)" "unprognostic (2.40e-2)" "unprognostic (1.67e-1)" "unprognostic (5.40e-2)" "unprognostic (1.11e-1)" "unprognostic (1.48e-1)" "unprognostic (1.02e-1)" "unprognostic (1.27e-1)" "unprognostic (3.82e-1)" "unprognostic (5.57e-3)" "unprognostic (1.28e-1)" "unprognostic (2.33e-1)" "unprognostic (1.84e-1)" "unprognostic (2.49e-3)" "potential prognostic favorable (4.40e-4)" "unprognostic (1.61e-1)" "unprognostic (2.64e-1)" "unprognostic (3.28e-3)" "unprognostic (7.51e-2)" "unprognostic (8.82e-2)" "unprognostic (5.38e-2)" "unprognostic (6.50e-3)" "unprognostic (3.68e-2)" "unprognostic (4.81e-3)" "unprognostic (1.10e-3)" "unprognostic (9.59e-2)" "unprognostic (2.01e-1)" "unprognostic (9.39e-2)" "unprognostic (7.57e-2)" "unprognostic (1.36e-2)" BTN3A1 "BT3.1, BTF5, BTN3.1, CD277" ENSG00000026950 "Butyrophilin subfamily 3 member A1" O00481 6 26402237-26415208 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cells: 96.5;Plasma cells: 57.4;T-cells: 78.2" "Cell type enriched" "Detected in many" 4 "leukocyte: 54.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - T-cells, Breast - T-cells, Skeletal muscle - Fibroblasts, Stomach - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" HPA012565 Approved Uncertain Vesicles NA NA "Cluster 1: T-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 10 Vesicles "HPA012565: " "unprognostic (2.38e-2)" "unprognostic (4.80e-2)" "unprognostic (2.24e-1)" "unprognostic (3.90e-2)" "unprognostic (7.58e-2)" "unprognostic (2.57e-1)" "unprognostic (8.94e-2)" "unprognostic (3.77e-2)" "unprognostic (1.61e-1)" "unprognostic (6.40e-2)" "unprognostic (4.75e-3)" "unprognostic (2.23e-2)" "unprognostic (3.61e-1)" "unprognostic (4.00e-2)" "potential prognostic favorable (1.71e-4)" "unprognostic (3.26e-2)" "unprognostic (9.18e-2)" "unprognostic (5.01e-2)" "unprognostic (2.68e-1)" "unprognostic (2.21e-2)" "unprognostic (2.93e-1)" "unprognostic (3.92e-2)" "unprognostic (4.22e-2)" "unprognostic (1.22e-1)" "unprognostic (3.49e-3)" "unprognostic (1.98e-1)" "unprognostic (3.56e-2)" "unprognostic (4.59e-1)" "unprognostic (2.49e-2)" "unprognostic (6.59e-2)" "unprognostic (2.98e-1)" BTN3A2 BTN3.2 ENSG00000186470 "Butyrophilin subfamily 3 member A2" P78410 6 26365159-26378320 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 83.3" "Cell type enhanced" "Detected in many" "Kupffer cells: 72.8;NK-cells: 124.4;Plasma cells: 101.9;Platelets: 115.4;T-cells: 105.5" "Cell type enhanced" "Detected in many" "leukocyte: 92.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - T-cells, Thyroid gland - T-cells" CAB019392 Uncertain NA NA "Cluster 1: T-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 11 "CAB019392: " "unprognostic (2.52e-2)" "unprognostic (1.27e-1)" "unprognostic (8.65e-3)" "unprognostic (7.46e-2)" "unprognostic (1.22e-1)" "unprognostic (4.37e-1)" "unprognostic (4.56e-2)" "unprognostic (2.62e-1)" "unprognostic (8.35e-2)" "unprognostic (1.93e-1)" "potential prognostic favorable (3.15e-4)" "unprognostic (2.94e-2)" "unprognostic (1.59e-1)" "unprognostic (7.85e-2)" "unprognostic (1.02e-2)" "unprognostic (3.56e-1)" "unprognostic (2.46e-1)" "unprognostic (1.87e-1)" "unprognostic (2.43e-1)" "unprognostic (4.98e-3)" "unprognostic (1.06e-1)" "unprognostic (3.97e-2)" "unprognostic (1.94e-1)" "unprognostic (3.13e-1)" "unprognostic (6.08e-3)" "unprognostic (1.56e-1)" "unprognostic (4.39e-2)" "unprognostic (1.11e-1)" "unprognostic (7.32e-3)" "unprognostic (3.70e-2)" "unprognostic (9.16e-2)" BTN3A3 "BTF3, BTN3.3" ENSG00000111801 "Butyrophilin subfamily 3 member A3" O00478 6 26440472-26453415 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Kupffer cells: 40.0;Late spermatids: 32.2;NK-cells: 28.0;T-cells: 24.1" "Cell type enhanced" "Detected in many" "leukocyte: 28.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Breast - T-cells" "HPA007110, HPA007904, HPA011871" Enhanced Approved "Nucleoplasm,Nuclear bodies,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 8: Immune cells - Immune response" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 10 "Nucleoplasm, Plasma membrane" "Nuclear bodies, Vesicles, Cytosol" "HPA007110: , HPA007904: , HPA011871: " "unprognostic (1.21e-3)" "unprognostic (8.61e-2)" "unprognostic (1.03e-1)" "unprognostic (1.89e-1)" "unprognostic (3.68e-2)" "unprognostic (3.60e-1)" "unprognostic (4.65e-2)" "unprognostic (8.72e-2)" "unprognostic (1.77e-1)" "unprognostic (1.43e-1)" "potential prognostic favorable (5.33e-4)" "unprognostic (1.25e-2)" "unprognostic (5.18e-2)" "validated prognostic favorable (9.24e-4)" "validated prognostic favorable (1.99e-4)" "unprognostic (6.35e-2)" "unprognostic (9.62e-2)" "unprognostic (2.33e-1)" "unprognostic (2.00e-1)" "unprognostic (2.34e-3)" "unprognostic (8.25e-2)" "unprognostic (4.13e-2)" "unprognostic (2.63e-1)" "unprognostic (1.80e-1)" "unprognostic (5.44e-3)" "unprognostic (3.65e-1)" "unprognostic (2.50e-1)" "unprognostic (2.14e-1)" "unprognostic (3.75e-2)" "unprognostic (5.95e-2)" "unprognostic (2.12e-1)" BTNL2 "BTL-II, BTN7, HSBLMHC1" ENSG00000204290 "Butyrophilin like 2" 6 32393339-32407181 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Other brain neurons: 1.1" "Cell type enhanced" "Detected in some" "hippocampal dentate gyrus: 2.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 14: Neurons - Synaptic function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 109: Neurons - Neuronal signaling" BTNL3 "BTN9.1, BTNLR" ENSG00000168903 "Butyrophilin like 3" Q6UXE8 5 180988846-181006727 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 65 "intestine: 108.6" "Cell type enhanced" "Detected in some" "Colonocytes: 135.1;Enteric stem cells: 28.3;Enteric transient amplifying cells: 51.6;Enterocytes: 264.1;Goblet cells: 96.3;Paneth cells: 42.5" "Cell type enriched" "Detected in single" 17 "endothelial cell: 3.7" "Cancer enhanced" "Detected in some" "Colon Adenocarcinoma (TCGA): 7.6;Rectum Adenocarcinoma (TCGA): 7.2" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 207 "neutrophil: 22.4" "Lineage enriched" "Detected in single" 207 "granulocytes: 22.4" "Group enriched" "Detected in some" 4 "colorectal cancer: 2.6;Gastric cancer: 1.0" "Colon - Colon enterocytes" NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" "unprognostic (1.15e-1)" "unprognostic (6.74e-2)" "unprognostic (1.81e-1)" "unprognostic (4.27e-2)" "unprognostic (2.10e-1)" "potential prognostic favorable (2.86e-4)" "unprognostic (4.96e-2)" "unprognostic (1.11e-2)" BTNL8 "BTN9.2, FLJ21458" ENSG00000113303 "Butyrophilin like 8" Q6UX41 5 180899077-180950906 "Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "intestine: 112.1" "Group enriched" "Detected in some" 4 "Colonocytes: 177.0;Enterocytes: 415.1;Foveolar cells: 163.2;Goblet cells: 150.0;Neutrophils: 345.0;Sertoli cells: 160.3" "Cell type enriched" "Detected in some" 7 "endothelial cell: 21.0" "Group enriched" "Detected in some" 12 "Colon Adenocarcinoma (TCGA): 8.6;Liver Hepatocellular Carcinoma (TCGA): 4.8;Pancreatic Adenocarcinoma (TCGA): 9.4;Rectum Adenocarcinoma (TCGA): 6.7;Stomach Adenocarcinoma (TCGA): 11.7" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 12 "neutrophil: 234.3" "Lineage enriched" "Detected in many" 221 "granulocytes: 234.3" "Group enriched" "Detected in some" 5 "colorectal cancer: 3.8;Esophageal cancer: 1.8;Gastric cancer: 3.5;pancreatic cancer: 2.0" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Kidney - Podocytes, Stomach - Gastric mucous cells" HPA039738 Enhanced NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 1 "HPA039738: " "unprognostic (3.12e-2)" "unprognostic (4.56e-2)" "unprognostic (1.13e-2)" "unprognostic (3.51e-2)" "unprognostic (1.71e-1)" "unprognostic (6.04e-3)" "unprognostic (6.27e-2)" "unprognostic (1.27e-1)" "unprognostic (1.52e-1)" BTNL9 "BTN8, FLJ32535" ENSG00000165810 "Butyrophilin like 9" Q6UXG8 5 181040225-181061521 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 235.9;breast: 196.9" "Cell type enriched" "Detected in many" 4 "Vascular endothelial cells: 361.4" "Cell type enhanced" "Detected in many" "endothelial cell: 549.0;lower rhombic lip: 143.4" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 24.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "lymphoma: 9.6" "Adipose visceral - Endothelial cells, Liver - Vascular endothelial cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA043429 Approved "Nuclear membrane,Vesicles" NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 49: Hindbrain - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" "Nuclear membrane" Vesicles "HPA043429: " "unprognostic (1.33e-2)" "unprognostic (1.14e-1)" "unprognostic (4.78e-3)" "unprognostic (6.66e-2)" "unprognostic (2.60e-2)" "unprognostic (3.51e-3)" "unprognostic (3.19e-1)" "unprognostic (2.34e-1)" "unprognostic (1.11e-1)" "unprognostic (2.12e-1)" "validated prognostic favorable (1.26e-6)" "validated prognostic favorable (1.93e-5)" "unprognostic (8.55e-2)" "validated prognostic favorable (4.61e-10)" "validated prognostic favorable (5.45e-6)" "potential prognostic favorable (6.50e-4)" "unprognostic (5.71e-3)" "unprognostic (1.80e-2)" "unprognostic (6.66e-2)" "unprognostic (1.77e-1)" "unprognostic (1.44e-1)" "unprognostic (1.30e-3)" "unprognostic (5.58e-2)" "unprognostic (3.80e-2)" "unprognostic (3.34e-3)" "unprognostic (9.10e-2)" "unprognostic (1.96e-1)" "unprognostic (4.60e-2)" "unprognostic (3.41e-1)" "unprognostic (2.54e-1)" "unprognostic (1.12e-1)" BTRC "beta-TrCP1, betaTrCP, bTrCP, bTrCP1, FBXW1A, Fwd1" ENSG00000166167 "Beta-transducin repeat containing E3 ubiquitin protein ligase" Q9Y297 10 101354033-101557321 "Predicted intracellular proteins" "Biological rhythms, Host-virus interaction, Ubl conjugation pathway, Wnt signaling pathway" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Sertoli cells: 395.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031156, CAB032986" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 52: Non-specific - Mitochondria" "Cluster 100: Stratified epithelial cells - Barrier functions" 248 Nucleoplasm "Plasma membrane, Cytosol" "CAB032986: , HPA031156: " "unprognostic (8.30e-2)" "unprognostic (3.54e-2)" "unprognostic (7.11e-2)" "unprognostic (9.83e-2)" "unprognostic (5.83e-2)" "unprognostic (3.18e-1)" "unprognostic (3.49e-1)" "potential prognostic favorable (9.97e-4)" "unprognostic (2.45e-1)" "unprognostic (5.04e-2)" "potential prognostic favorable (8.46e-6)" "unprognostic (1.83e-3)" "unprognostic (2.02e-1)" "unprognostic (2.75e-2)" "unprognostic (8.53e-2)" "unprognostic (2.68e-1)" "unprognostic (5.22e-2)" "unprognostic (1.65e-2)" "unprognostic (8.61e-2)" "validated prognostic unfavorable (4.78e-4)" "validated prognostic unfavorable (1.04e-4)" "unprognostic (3.31e-2)" "unprognostic (1.14e-2)" "unprognostic (4.26e-1)" "unprognostic (4.69e-2)" "unprognostic (2.38e-1)" "unprognostic (7.90e-2)" "unprognostic (2.37e-1)" "unprognostic (3.02e-2)" "unprognostic (2.53e-1)" "unprognostic (5.92e-2)" BUB1 "BUB1A, BUB1L, hBUB1" ENSG00000169679 "BUB1 mitotic checkpoint serine/threonine kinase" O43683 2 110637528-110678063 "Enzymes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Chromosome partition, Host-virus interaction, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Intellectual disability, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 11.2;lymphoid tissue: 25.6;testis: 28.3" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 43.6;Early primary spermatocytes: 119.8;Erythrocyte progenitors: 108.0;Granulosa cells: 39.7;Late primary spermatocytes: 75.2;Megakaryocyte progenitors: 67.6;Monocyte progenitors: 109.1;Neutrophil progenitors: 36.7;Oocytes: 50.7;Plasma cells: 44.6" "Cell type enhanced" "Detected in some" "leukocyte: 3.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Region enhanced" "Detected in single" "white matter: 1.7" "Not detected" "Not detected" HPA006123 Supported Nucleoplasm,Cytosol NA Yes "Cluster 5: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 11: White matter - Signal transduction" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Non-specific - Cell proliferation" 37 Nucleoplasm Cytosol "HPA006123: " "unprognostic (2.01e-1)" "unprognostic (1.82e-1)" "unprognostic (1.37e-1)" "unprognostic (2.83e-2)" "unprognostic (1.32e-2)" "unprognostic (1.66e-1)" "unprognostic (2.69e-1)" "unprognostic (3.96e-2)" "unprognostic (1.63e-1)" "potential prognostic unfavorable (8.26e-5)" "validated prognostic unfavorable (2.38e-5)" "validated prognostic unfavorable (3.02e-4)" "potential prognostic unfavorable (1.62e-6)" "validated prognostic unfavorable (2.73e-5)" "validated prognostic unfavorable (5.06e-7)" "potential prognostic unfavorable (4.27e-5)" "unprognostic (3.43e-3)" "unprognostic (1.18e-1)" "unprognostic (3.82e-2)" "unprognostic (6.74e-2)" "unprognostic (1.20e-1)" "potential prognostic unfavorable (5.63e-5)" "unprognostic (1.17e-2)" "unprognostic (6.59e-2)" "unprognostic (1.88e-2)" "unprognostic (1.63e-1)" "unprognostic (1.62e-2)" "unprognostic (1.56e-2)" "unprognostic (3.78e-1)" "unprognostic (6.01e-2)" "unprognostic (1.92e-1)" BUB1B "Bub1A, BUBR1, MAD3L, SSK1" ENSG00000156970 "BUB1 mitotic checkpoint serine/threonine kinase B" O60566 15 40161023-40221123 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 16.8;lymphoid tissue: 33.2;testis: 20.8" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 40.1;Differentiating spermatogonia: 23.8;Early primary spermatocytes: 64.0;Erythrocyte progenitors: 71.3;Megakaryocyte progenitors: 39.4;Monocyte progenitors: 80.1;Neutrophil progenitors: 43.7;Plasma cells: 18.4;Retinal ganglion cells: 23.2" "Cell type enriched" "Detected in many" 10 "choroid plexus epithelial cell: 43.2" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in single" 17 "choroid plexus: 17.0" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA008419 Supported "Basal body,Cytosol" Yes Yes "Cluster 14: Non-specific - Unknown function" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 36: Choroid plexus - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 27: Non-specific - Cell proliferation" 74 Cytosol "Basal body" "HPA008419: " "potential prognostic unfavorable (1.00e-3)" "unprognostic (6.05e-2)" "unprognostic (3.03e-1)" "unprognostic (4.67e-1)" "unprognostic (1.54e-1)" "unprognostic (4.05e-1)" "unprognostic (1.89e-1)" "unprognostic (7.91e-3)" "unprognostic (2.84e-2)" "potential prognostic unfavorable (3.70e-4)" "validated prognostic unfavorable (4.04e-8)" "validated prognostic unfavorable (1.26e-5)" "potential prognostic unfavorable (4.10e-11)" "validated prognostic unfavorable (6.64e-6)" "validated prognostic unfavorable (4.00e-8)" "validated prognostic unfavorable (1.88e-5)" "validated prognostic unfavorable (2.38e-4)" "unprognostic (7.44e-2)" "unprognostic (2.31e-2)" "unprognostic (9.29e-2)" "unprognostic (4.81e-2)" "potential prognostic unfavorable (5.41e-4)" "unprognostic (1.46e-2)" "unprognostic (6.03e-2)" "unprognostic (1.63e-2)" "unprognostic (8.86e-2)" "unprognostic (4.12e-2)" "unprognostic (6.13e-2)" "unprognostic (1.73e-1)" "unprognostic (2.33e-1)" "unprognostic (1.72e-2)" BUB3 BUB3L ENSG00000154473 "BUB3 mitotic checkpoint protein" O43684 10 123154402-123170467 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Meiosis, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 279.3;Late spermatids: 232.1;Oocytes: 391.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003601, CAB037075, HPA071982" Supported Enhanced Nucleoplasm NA Yes 16000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 49: Hindbrain - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 27: Non-specific - Cell proliferation" 43 Nucleoplasm "CAB037075: , HPA003601: , HPA071982: " "unprognostic (1.11e-2)" "unprognostic (4.56e-1)" "unprognostic (3.47e-2)" "unprognostic (8.80e-2)" "unprognostic (2.19e-1)" "unprognostic (9.55e-2)" "unprognostic (9.23e-2)" "potential prognostic favorable (1.82e-4)" "unprognostic (6.96e-2)" "potential prognostic unfavorable (5.67e-4)" "potential prognostic favorable (1.03e-5)" "unprognostic (2.62e-2)" "unprognostic (2.14e-2)" "potential prognostic unfavorable (2.19e-5)" "unprognostic (1.59e-2)" "validated prognostic unfavorable (6.14e-5)" "validated prognostic unfavorable (4.00e-4)" "unprognostic (1.25e-1)" "unprognostic (1.72e-1)" "unprognostic (2.10e-1)" "unprognostic (4.99e-2)" "unprognostic (1.95e-3)" "unprognostic (1.28e-2)" "unprognostic (2.33e-3)" "unprognostic (5.90e-3)" "unprognostic (1.15e-1)" "unprognostic (1.97e-1)" "unprognostic (7.32e-2)" "unprognostic (1.49e-1)" "unprognostic (3.88e-2)" "unprognostic (4.38e-2)" BUD13 "Cwc26, fSAP71, MGC13125" ENSG00000137656 "BUD13 homolog" Q9BRD0 11 116748170-116772987 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 62.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038340, HPA038341" Enhanced Enhanced Nucleoplasm NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 39: Testis - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 20: Non-specific - Transcription regulation" 13 Nucleoplasm "HPA038340: , HPA038341: " "unprognostic (2.91e-2)" "unprognostic (1.68e-2)" "unprognostic (7.53e-2)" "unprognostic (1.28e-2)" "unprognostic (1.90e-1)" "unprognostic (2.59e-2)" "unprognostic (5.59e-2)" "unprognostic (2.11e-3)" "unprognostic (1.43e-1)" "unprognostic (8.59e-3)" "potential prognostic favorable (1.11e-5)" "unprognostic (3.82e-3)" "unprognostic (2.34e-2)" "unprognostic (1.07e-3)" "unprognostic (2.87e-1)" "unprognostic (2.30e-1)" "unprognostic (9.94e-3)" "unprognostic (7.00e-2)" "unprognostic (2.00e-1)" "unprognostic (1.71e-1)" "unprognostic (3.15e-2)" "unprognostic (7.47e-2)" "unprognostic (4.13e-2)" "unprognostic (1.49e-1)" "unprognostic (1.47e-2)" "unprognostic (1.20e-1)" "potential prognostic unfavorable (2.88e-4)" "unprognostic (1.49e-1)" "unprognostic (1.85e-1)" "unprognostic (8.19e-2)" "unprognostic (2.03e-1)" BUD23 "MERM1, MGC19709, MGC2022, MGC5140, PP3381, WBMT, WBSCR22" ENSG00000071462 "BUD23 rRNA methyltransferase and ribosome maturation factor" O43709 7 73683597-73698212 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Transferase" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 619.6;Early primary spermatocytes: 723.4;Undifferentiated spermatogonia: 475.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052185 Approved Supported Nucleoplasm,Nucleoli Yes No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 21: Non-specific - Metabolism" "Cluster 39: Non-specific - Transcription" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 19 "Nucleoplasm, Nucleoli" "HPA052185: " "unprognostic (8.46e-2)" "unprognostic (2.25e-1)" "unprognostic (3.41e-2)" "unprognostic (1.89e-1)" "unprognostic (2.72e-1)" "potential prognostic unfavorable (4.11e-5)" "unprognostic (2.77e-2)" "unprognostic (1.06e-2)" "unprognostic (5.78e-3)" "unprognostic (3.87e-2)" "unprognostic (1.05e-3)" "unprognostic (5.15e-2)" "potential prognostic unfavorable (2.43e-5)" "unprognostic (1.02e-2)" "unprognostic (3.85e-1)" "unprognostic (1.31e-1)" "unprognostic (3.89e-1)" "unprognostic (1.79e-1)" "unprognostic (2.42e-2)" "unprognostic (1.68e-1)" "unprognostic (3.29e-1)" "unprognostic (6.51e-2)" "unprognostic (2.76e-2)" "unprognostic (9.99e-2)" "unprognostic (2.65e-1)" "unprognostic (3.59e-2)" "unprognostic (1.64e-1)" "unprognostic (5.59e-2)" "unprognostic (6.93e-2)" BUD31 "Cwc14, EDG-2, EDG2, fSAP17, G10, YCR063W" ENSG00000106245 "BUD31 homolog" P41223 7 99408641-99419616 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 511.8;Late primary spermatocytes: 485.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028943 Approved Supported Nucleoplasm,Microtubules,Centrosome NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 39: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 16 Nucleoplasm "Microtubules, Centrosome" "HPA028943: " "unprognostic (1.41e-2)" "unprognostic (2.52e-1)" "unprognostic (2.83e-2)" "unprognostic (3.07e-1)" "unprognostic (6.83e-3)" "unprognostic (4.84e-3)" "unprognostic (1.19e-2)" "unprognostic (4.42e-2)" "unprognostic (5.94e-3)" "potential prognostic unfavorable (9.73e-6)" "unprognostic (2.42e-3)" "unprognostic (3.79e-3)" "unprognostic (1.64e-1)" "validated prognostic unfavorable (1.00e-3)" "validated prognostic unfavorable (9.02e-4)" "unprognostic (4.62e-3)" "unprognostic (8.40e-3)" "unprognostic (1.32e-2)" "unprognostic (1.57e-1)" "unprognostic (4.51e-2)" "unprognostic (1.66e-1)" "unprognostic (1.55e-2)" "potential prognostic unfavorable (4.39e-5)" "unprognostic (3.51e-1)" "unprognostic (1.69e-1)" "unprognostic (1.80e-1)" "unprognostic (1.63e-1)" "unprognostic (2.56e-1)" "unprognostic (1.13e-1)" "unprognostic (2.19e-1)" "unprognostic (7.37e-2)" BVES "HBVES, POP1, POPDC1" ENSG00000112276 "Blood vessel epicardial substance" Q8NE79 6 105096822-105137157 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cell adhesion" "Developmental protein" "Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 26.0;skeletal muscle: 41.0;tongue: 27.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 46.0;Early spermatids: 30.7;Late primary spermatocytes: 57.0;Late spermatids: 93.9;Myonuclei: 119.5;Myosatellite cells: 22.1;Pituicytes/FSCs: 25.8;Smooth muscle cells: 23.9" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 25.0;oligodendrocyte: 23.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 16.5" "Adipose subcutaneous - Smooth muscle cells, Prostate - Smooth muscle cells, Stomach - Chief cells, Testis - Early spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA014788, HPA018176" Enhanced Supported "Plasma membrane,Cell Junctions" Yes NA "Cluster 41: Striated muscle - Muscle contraction" "Cluster 30: White matter - Myelination" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 2 "Plasma membrane, Cell Junctions" "HPA014788: , HPA018176: " "unprognostic (1.30e-1)" "unprognostic (2.02e-1)" "unprognostic (2.35e-1)" "unprognostic (3.16e-1)" "unprognostic (1.19e-1)" "unprognostic (1.16e-1)" "unprognostic (4.26e-1)" "unprognostic (7.36e-2)" "unprognostic (1.80e-2)" "unprognostic (2.41e-1)" "unprognostic (2.61e-2)" "unprognostic (7.33e-3)" "unprognostic (3.88e-2)" "unprognostic (2.78e-2)" "unprognostic (1.37e-1)" "unprognostic (7.02e-2)" "unprognostic (4.27e-2)" "unprognostic (2.56e-1)" "unprognostic (3.76e-2)" "unprognostic (3.04e-1)" "unprognostic (2.24e-2)" BYSL Enp1 ENSG00000112578 "Bystin like" Q13895 6 41921499-41933046 "Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 32.9;Epicardial cells: 36.4;Esophageal basal cells: 42.0;Oocytes: 59.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031217, HPA031219" Enhanced Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 288 "Nucleoli, Nucleoli rim, Mitotic chromosome" Nucleoplasm "HPA031217: , HPA031219: " "unprognostic (1.15e-2)" "unprognostic (2.50e-2)" "unprognostic (2.45e-1)" "unprognostic (1.39e-1)" "unprognostic (1.20e-1)" "unprognostic (1.51e-1)" "unprognostic (1.64e-2)" "unprognostic (4.14e-3)" "unprognostic (7.54e-3)" "unprognostic (7.11e-2)" "unprognostic (6.79e-2)" "unprognostic (3.52e-1)" "potential prognostic unfavorable (6.44e-4)" "validated prognostic unfavorable (6.91e-4)" "validated prognostic unfavorable (1.23e-6)" "unprognostic (3.31e-3)" "unprognostic (9.86e-3)" "unprognostic (2.90e-1)" "unprognostic (7.35e-3)" "unprognostic (9.05e-2)" "unprognostic (2.04e-2)" "unprognostic (5.31e-2)" "unprognostic (5.30e-1)" "unprognostic (1.04e-1)" "unprognostic (9.34e-3)" "unprognostic (1.40e-1)" "unprognostic (3.28e-1)" "unprognostic (8.12e-2)" "unprognostic (1.64e-1)" "potential prognostic unfavorable (1.68e-4)" "unprognostic (4.95e-2)" BZW1 "5MP2, BZAP45, KIAA0005" ENSG00000082153 "Basic leucine zipper and W2 domains 1" Q7L1Q6 2 200810594-200827338 "Predicted intracellular proteins" "Transcription, Transcription regulation, Translation regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Late spermatids: 2864.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047288, HPA053272" Uncertain Approved Vesicles NA NA 170000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 39: Testis - Nuclear processes" "Cluster 21: Non-specific - Metabolism" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 9 Vesicles "HPA047288: , HPA053272: " "unprognostic (1.46e-2)" "unprognostic (3.17e-3)" "unprognostic (4.36e-2)" "unprognostic (1.39e-2)" "unprognostic (5.01e-2)" "unprognostic (3.46e-2)" "unprognostic (2.45e-1)" "unprognostic (4.79e-3)" "unprognostic (2.55e-2)" "unprognostic (8.56e-3)" "potential prognostic favorable (1.90e-6)" "unprognostic (1.74e-1)" "unprognostic (4.53e-2)" "unprognostic (4.57e-3)" "unprognostic (1.99e-3)" "potential prognostic unfavorable (6.03e-4)" "unprognostic (1.00e-2)" "unprognostic (3.12e-2)" "unprognostic (1.42e-1)" "unprognostic (1.65e-1)" "unprognostic (1.24e-1)" "validated prognostic unfavorable (3.05e-4)" "validated prognostic unfavorable (5.18e-4)" "unprognostic (1.41e-2)" "unprognostic (3.45e-1)" "unprognostic (6.73e-2)" "unprognostic (1.78e-1)" "unprognostic (1.72e-1)" "unprognostic (2.96e-1)" "unprognostic (3.87e-2)" "unprognostic (2.00e-1)" BZW2 "5MP1, HSPC028, MST017, MSTP017" ENSG00000136261 "Basic leucine zipper and W2 domains 2" Q9Y6E2 7 16646131-16706523 "Predicted intracellular proteins" "Translation regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 248.4;skeletal muscle: 344.4;tongue: 241.7" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 1570.7;Migrating cytotrophoblasts: 495.6;Syncytiotrophoblasts: 1200.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022813, HPA026709" Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" NA NA 19000 "Cluster 13: Non-specific - Mitochondria" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 53: Neurons - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 14 "Plasma membrane, Actin filaments, Cytosol" "HPA022813: , HPA026709: " "unprognostic (5.69e-3)" "potential prognostic unfavorable (6.42e-4)" "unprognostic (2.97e-2)" "unprognostic (1.08e-2)" "unprognostic (3.29e-3)" "unprognostic (2.28e-1)" "unprognostic (2.84e-1)" "unprognostic (2.44e-1)" "potential prognostic unfavorable (6.90e-4)" "potential prognostic unfavorable (5.21e-4)" "unprognostic (2.97e-3)" "unprognostic (1.56e-3)" "unprognostic (5.39e-3)" "validated prognostic unfavorable (3.48e-7)" "validated prognostic unfavorable (4.52e-5)" "validated prognostic unfavorable (4.27e-4)" "validated prognostic unfavorable (7.04e-4)" "unprognostic (1.47e-2)" "unprognostic (7.69e-2)" "unprognostic (5.87e-2)" "unprognostic (5.66e-3)" "potential prognostic unfavorable (4.19e-4)" "unprognostic (1.29e-1)" "unprognostic (6.88e-3)" "unprognostic (8.81e-2)" "unprognostic (7.92e-2)" "unprognostic (4.69e-3)" "unprognostic (1.20e-1)" "unprognostic (6.80e-2)" "unprognostic (6.29e-3)" "unprognostic (2.18e-1)" C10orf105 FLJ00245 ENSG00000214688 "Chromosome 10 open reading frame 105" Q8TEF2 10 71711701-71737824 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 12.8" "Cell type enhanced" "Detected in some" "Adipocytes: 10.7;cDC: 9.9;Early spermatids: 11.0;Ependymal cells: 48.4;Erythrocyte progenitors: 12.5;Late spermatids: 7.4;Müller glia: 12.0;Neutrophils: 22.9" "Cell type enriched" "Detected in some" 11 "ependymal cell: 66.9" "Cancer enriched" "Detected in single" 7 "Glioblastoma Multiforme (TCGA): 2.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.8;non-classical monocyte: 2.1" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells, Spleen - Neutrophils_2, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 46: Brainstem - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" "unprognostic (1.95e-3)" "unprognostic (1.75e-1)" "unprognostic (8.40e-2)" C10orf120 bA318C4.1 ENSG00000183559 "Chromosome 10 open reading frame 120" Q5SQS8 10 122697709-122699846 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 161 "testis: 29.0" "Cell type enriched" "Detected in some" 5 "Early spermatids: 809.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" C10orf143 LINC00959 ENSG00000237489 "Chromosome 10 open reading frame 143" A0A1B0GUT2 10 130020025-130110830 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 24: Non-specific - Transcription" "Cluster 39: Astrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 7: Non-specific - Transcription" "unprognostic (8.16e-2)" "unprognostic (1.72e-1)" "unprognostic (1.20e-2)" "unprognostic (4.15e-1)" "unprognostic (2.10e-1)" "unprognostic (6.39e-2)" "unprognostic (1.43e-1)" "unprognostic (5.88e-3)" "unprognostic (1.90e-1)" "unprognostic (4.14e-2)" "unprognostic (2.55e-2)" "potential prognostic favorable (6.71e-8)" "potential prognostic favorable (5.84e-4)" "unprognostic (5.52e-3)" "unprognostic (2.33e-2)" "unprognostic (1.63e-1)" "unprognostic (1.24e-2)" "unprognostic (1.32e-1)" "unprognostic (4.49e-3)" "unprognostic (2.34e-1)" "unprognostic (1.77e-2)" "unprognostic (1.60e-1)" "unprognostic (7.41e-2)" "unprognostic (2.69e-1)" "unprognostic (1.09e-1)" "unprognostic (1.89e-2)" "unprognostic (6.34e-2)" C10orf53 Em:AC069546.1 ENSG00000178645 "Chromosome 10 open reading frame 53" Q8N6V4 10 49679651-49710261 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 29 "testis: 10.9" "Cell type enriched" "Detected in some" 5 "Late spermatids: 2419.4" "Cell type enriched" "Detected in single" 22 "ependymal cell: 13.5" "Cancer enhanced" "Detected in some" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 2.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA037951 Enhanced NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 48: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" "HPA037951: " "unprognostic (1.51e-2)" "unprognostic (1.35e-1)" "unprognostic (1.43e-1)" "unprognostic (1.99e-2)" "unprognostic (5.10e-2)" C10orf62 bA548K23.1 ENSG00000203942 "Chromosome 10 open reading frame 62" Q5T681 10 97589721-97590934 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 292 "testis: 263.0" "Cell type enriched" "Detected in some" 4 "Late spermatids: 292.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" HPA072947 Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 13 Cytosol "Nucleoplasm, Vesicles" "HPA072947: " C10orf67 "bA215C7.4, C10orf115, LINC01552, MGC46732" ENSG00000179133 "Chromosome 10 open reading frame 67" Q8IYJ2 10 23202696-23344845 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 5.4;fallopian tube: 4.6;testis: 11.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 59.4;Choroid plexus epithelial cells: 67.1;Early primary spermatocytes: 98.3;Endometrial ciliated cells: 50.0;Ependymal cells: 110.4;Epididymal efferent duct ciliated cells: 92.8;Fallopian tube ciliated cells: 93.2;Late primary spermatocytes: 123.5;Late spermatids: 79.1;Proximal tubule cells: 44.3;Respiratory ciliated cells: 166.1;Thyrotrophs: 38.3" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 54.8;ependymal cell: 122.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.2" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in some" "cervical cancer: 3.4" "Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA038131 Approved Approved Vesicles,Microtubules,Mitochondria NA No "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 3: Early primary spermatocytes - Early meiosis" 3 "Vesicles, Microtubules, Mitochondria" "HPA038131: " "unprognostic (4.45e-2)" "potential prognostic favorable (1.98e-4)" "unprognostic (3.76e-2)" "unprognostic (2.87e-2)" "unprognostic (2.72e-2)" "unprognostic (3.31e-1)" "unprognostic (2.16e-2)" C10orf71 "CEFIP, FLJ45913" ENSG00000177354 "Chromosome 10 open reading frame 71" Q711Q0 10 49299170-49327492 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "skeletal muscle: 262.5;tongue: 76.5" "Cell type enriched" "Detected in some" 7 "Myonuclei: 461.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Head and Neck Squamous Cell Carcinoma (TCGA): 1.2;Kidney Chromophobe (TCGA): 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Sarcoma: 1.5;thyroid cancer: 1.5" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA057556 Approved Nucleoplasm,Mitochondria NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 55: Myocytes - Oxidative muscle function" Nucleoplasm Mitochondria "HPA057556: " "unprognostic (1.96e-2)" "unprognostic (2.24e-3)" C10orf82 "Em:AC016825.4, MGC33547" ENSG00000165863 "Chromosome 10 open reading frame 82" Q8WW14 10 116663696-116670264 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "testis: 69.0" "Group enriched" "Detected in some" 8 "Early spermatids: 1246.2;Late spermatids: 2527.3" "Cell type enhanced" "Detected in many" "deep-layer near-projecting: 7.1" "Cancer enhanced" "Detected in some" "Breast Invasive Carcinoma (TCGA): 2.0;Testicular Germ Cell Tumor (TCGA): 2.0" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 103 "basophil: 10.2" "Lineage enriched" "Detected in single" 103 "granulocytes: 10.2" "Cancer enhanced" "Detected in some" "testis cancer: 2.3" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Colon - Enteric glia cells, Testis - Late spermatids" "Not detected" "Not detected" HPA043022 Uncertain Mitochondria Yes NA "Cluster 46: Basophils - Proteolysis" "Cluster 23: Testis - Spermatogenesis" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 27: Breast cancer - Unknown function" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" Mitochondria "HPA043022: " "unprognostic (1.61e-1)" "unprognostic (4.08e-2)" "unprognostic (1.54e-1)" "unprognostic (1.28e-1)" "unprognostic (7.18e-2)" C10orf88 "Em:AC073585.5, FLJ13490, PAAT" ENSG00000119965 "Chromosome 10 open reading frame 88" Q9H8K7 10 122930901-122954311 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 57.2;Early spermatids: 114.3;Late primary spermatocytes: 162.1;Late spermatids: 51.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039681, HPA040991" Approved NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" 64 "HPA039681: , HPA040991: " "unprognostic (9.89e-2)" "unprognostic (1.72e-1)" "unprognostic (1.32e-1)" "unprognostic (6.70e-2)" "unprognostic (2.17e-1)" "unprognostic (6.96e-2)" "unprognostic (3.45e-1)" "unprognostic (1.01e-3)" "unprognostic (6.21e-2)" "unprognostic (1.38e-1)" "unprognostic (1.20e-3)" "unprognostic (1.55e-1)" "unprognostic (1.81e-1)" "potential prognostic unfavorable (7.92e-4)" "unprognostic (8.81e-2)" "unprognostic (2.37e-1)" "unprognostic (7.71e-2)" "unprognostic (9.08e-2)" "unprognostic (1.01e-1)" "unprognostic (7.61e-2)" "potential prognostic unfavorable (5.16e-5)" "unprognostic (9.28e-3)" "unprognostic (2.23e-2)" "unprognostic (1.01e-1)" "unprognostic (3.06e-2)" "unprognostic (4.35e-2)" "unprognostic (1.07e-1)" "unprognostic (2.36e-1)" "unprognostic (2.52e-1)" "unprognostic (1.98e-2)" "unprognostic (3.35e-1)" C10orf90 "bA422P15.2, FATS, FLJ32938" ENSG00000154493 "Chromosome 10 open reading frame 90" Q96M02 10 126424997-126798708 "Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 18.7;salivary gland: 5.7;testis: 5.8" "Cell type enhanced" "Detected in many" "Early spermatids: 227.0;Late primary spermatocytes: 71.6;Late spermatids: 257.4;Melanocytes: 111.0;Oligodendrocyte progenitor cells: 330.0;Oligodendrocytes: 1102.3;Salivary acinar cells: 126.3" "Group enriched" "Detected in many" 4 "committed oligodendrocyte precursor: 613.9;oligodendrocyte: 1414.6;oligodendrocyte precursor cell: 364.8" "Cancer enriched" "Detected in some" 5 "Skin Cutaneous Melanoma (TCGA): 19.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 9 "skin cancer: 28.3" "Adipose visceral - Adipocytes (Visceral), Skin - Eccrine sweat gland cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038648, HPA075229" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 80: Oligodendrocytes - Myelination" 1 Cytosol Nucleoplasm "HPA038648: , HPA075229: " "unprognostic (3.97e-2)" "unprognostic (5.84e-2)" "unprognostic (6.55e-2)" C10orf95 FLJ14280 ENSG00000120055 "Chromosome 10 open reading frame 95" 10 102449837-102451543 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "fallopian tube: 9.1" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 33.7;Epididymal efferent duct ciliated cells: 53.7;Fallopian tube ciliated cells: 71.9;Oocytes: 46.1;Respiratory ciliated cells: 83.0;Syncytiotrophoblasts: 52.2;Tuft cells: 46.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in single" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 40: Non-specific - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" "unprognostic (1.71e-2)" "unprognostic (9.71e-2)" "unprognostic (2.05e-1)" "unprognostic (1.02e-1)" "unprognostic (1.07e-3)" "unprognostic (2.02e-1)" "unprognostic (1.15e-1)" "unprognostic (4.09e-2)" "unprognostic (1.16e-1)" "unprognostic (3.78e-3)" "unprognostic (6.68e-3)" "unprognostic (7.51e-3)" "unprognostic (7.28e-2)" "unprognostic (7.71e-2)" "unprognostic (1.33e-3)" "unprognostic (5.54e-2)" "unprognostic (1.13e-1)" "unprognostic (4.58e-3)" "unprognostic (1.96e-1)" "unprognostic (9.51e-2)" "unprognostic (2.33e-2)" "unprognostic (4.01e-1)" "unprognostic (5.36e-2)" "unprognostic (1.89e-2)" "unprognostic (2.74e-2)" "unprognostic (2.22e-1)" "unprognostic (2.19e-1)" "unprognostic (1.08e-1)" "unprognostic (1.89e-1)" C11orf1 FLJ23499 ENSG00000137720 "Chromosome 11 open reading frame 1" Q9H5F2 11 111878935-111885975 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Late spermatids: 1840.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Skeletal muscle - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038410, HPA057519" Uncertain Enhanced Nucleoplasm NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 72: Kidney - Transmembrane transport" "Cluster 21: Non-specific - Metabolism" "Cluster 24: Non-specific - Unknown function" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 32 Nucleoplasm "HPA038410: , HPA057519: " "unprognostic (2.30e-1)" "unprognostic (3.22e-2)" "unprognostic (2.19e-1)" "unprognostic (2.11e-1)" "unprognostic (5.18e-2)" "unprognostic (2.35e-2)" "unprognostic (2.18e-1)" "unprognostic (1.09e-1)" "unprognostic (3.92e-2)" "unprognostic (4.43e-1)" "validated prognostic favorable (2.01e-7)" "validated prognostic favorable (5.33e-5)" "unprognostic (2.70e-2)" "unprognostic (9.11e-2)" "unprognostic (6.89e-3)" "unprognostic (7.62e-2)" "unprognostic (1.99e-2)" "unprognostic (1.26e-1)" "unprognostic (9.63e-2)" "unprognostic (9.48e-2)" "unprognostic (1.44e-1)" "unprognostic (5.96e-3)" "unprognostic (9.10e-2)" "unprognostic (8.86e-2)" "unprognostic (1.39e-2)" "unprognostic (5.24e-2)" "unprognostic (8.47e-2)" "unprognostic (4.48e-1)" "unprognostic (1.96e-1)" "unprognostic (9.22e-2)" "unprognostic (3.00e-3)" C11orf16 ENSG00000176029 "Chromosome 11 open reading frame 16" Q9NQ32 11 8920076-8933006 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 13.3;fallopian tube: 12.1;lymphoid tissue: 5.8" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 42.8;Endometrial ciliated cells: 64.6;Ependymal cells: 65.5;Epididymal efferent duct ciliated cells: 60.4;Fallopian tube ciliated cells: 94.0;Respiratory ciliated cells: 240.4;Respiratory ionocytes: 236.2;Salivary ionocytes: 92.3" "Group enriched" "Detected in some" 54 "choroid plexus epithelial cell: 31.3;ependymal cell: 70.5" "Cancer enhanced" "Detected in some" "Lung Adenocarcinoma (TCGA): 1.6;Uterine Corpus Endometrial Carcinoma (TCGA): 2.9" "Region enhanced" "Detected in many" "choroid plexus: 13.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary gland ductal cells, Testis - Early spermatids" "Low region specificity" "Detected in some" HPA040644 Uncertain "Endoplasmic reticulum,Vesicles" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" "Endoplasmic reticulum" Vesicles "HPA040644: " "unprognostic (1.68e-1)" "potential prognostic favorable (4.39e-4)" "unprognostic (1.81e-2)" "unprognostic (4.30e-2)" C11orf21 ENSG00000110665 "Chromosome 11 open reading frame 21" Q9P2W6 11 2295628-2303049 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 6 "bone marrow: 47.6;heart muscle: 19.4;lymphoid tissue: 15.0" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 221.8;cDC: 18.4;Epicardial cells: 20.5;Megakaryocyte progenitors: 24.0;Megakaryocytes: 74.2;Monocyte progenitors: 24.8;Neutrophil progenitors: 53.1;Neutrophils: 21.7;NK-cells: 30.0;Platelets: 91.6" "Cell type enriched" "Detected in some" 14 "leukocyte: 27.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in some" 9 "Leukemia: 24.8" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Heart muscle - Cardiomyocytes, Kidney - T-cells, Minor Salivary Gland - T-cells, Prostate - T-cells, Thyroid gland - T-cells" HPA037607 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" Nucleoplasm Cytosol "HPA037607: " "unprognostic (2.26e-3)" "unprognostic (2.77e-2)" "unprognostic (9.27e-2)" "unprognostic (3.69e-2)" "unprognostic (1.41e-1)" "unprognostic (1.81e-3)" "unprognostic (1.03e-1)" "unprognostic (7.82e-2)" "unprognostic (1.47e-1)" "unprognostic (4.05e-2)" C11orf24 DM4E3 ENSG00000171067 "Chromosome 11 open reading frame 24" Q96F05 11 68261338-68272001 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 182.6;Goblet cells: 63.1;Hepatocytes: 140.7;Plasma cells: 74.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Skin - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012411, HPA012748" Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 77: Intestine - Digestion" "Cluster 30: White matter - Myelination" "Cluster 24: Non-specific - Unknown function" "Cluster 1: Enterocytes - Absorption and Digestion" 7 "Nucleoplasm, Golgi apparatus" Vesicles "HPA012411: , HPA012748: " "unprognostic (1.01e-1)" "potential prognostic unfavorable (7.04e-4)" "unprognostic (2.53e-1)" "unprognostic (3.12e-3)" "unprognostic (1.00e-1)" "unprognostic (4.00e-1)" "unprognostic (3.42e-2)" "unprognostic (8.92e-3)" "unprognostic (8.66e-3)" "unprognostic (5.59e-2)" "unprognostic (3.06e-2)" "potential prognostic unfavorable (2.43e-4)" "unprognostic (1.18e-2)" "unprognostic (9.01e-2)" "unprognostic (4.45e-2)" "potential prognostic unfavorable (2.60e-4)" "unprognostic (1.77e-3)" "unprognostic (4.57e-2)" "unprognostic (7.25e-2)" "unprognostic (2.18e-2)" "unprognostic (8.97e-3)" "unprognostic (2.72e-2)" "unprognostic (2.44e-1)" "unprognostic (8.02e-2)" "unprognostic (3.45e-1)" "unprognostic (1.42e-2)" "unprognostic (1.32e-1)" "unprognostic (1.89e-1)" "unprognostic (1.17e-1)" "unprognostic (2.04e-2)" "unprognostic (3.92e-2)" C11orf42 MGC34805 ENSG00000180878 "Chromosome 11 open reading frame 42" Q8N5U0 11 6205557-6211135 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "testis: 24.3" "Cell type enriched" "Detected in some" 6 "Late spermatids: 1337.0" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA063404 Enhanced Approved "Nuclear membrane,Vesicles,Plasma membrane" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 15: Non-specific - Transcription" "Cluster 19: Non-specific - Unknown function" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" "Plasma membrane" "Nuclear membrane, Vesicles" "HPA063404: " "unprognostic (1.22e-1)" "unprognostic (4.49e-1)" "unprognostic (6.51e-2)" C11orf52 "FLJ25219, MGC14839" ENSG00000149300 "Chromosome 11 open reading frame 52" Q96A22 11 111918032-111926871 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 1.5;Brain excitatory neurons: 1.8;Choroid plexus epithelial cells: 5.0;Ependymal cells: 1.7;Oligodendrocytes: 1.0" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 9.1;upper rhombic lip: 5.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Heart muscle - Macrophages, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038387, HPA038388" Uncertain Enhanced "Cell Junctions" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 25: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 1 "Cell Junctions" "HPA038387: , HPA038388: " "unprognostic (2.33e-1)" "unprognostic (1.72e-1)" "unprognostic (2.42e-1)" "unprognostic (4.69e-2)" "unprognostic (1.58e-2)" "unprognostic (2.99e-1)" "unprognostic (2.83e-1)" "unprognostic (5.96e-2)" "potential prognostic favorable (3.24e-12)" "unprognostic (1.82e-3)" "unprognostic (5.17e-3)" "unprognostic (5.67e-3)" "unprognostic (2.08e-1)" "unprognostic (6.72e-2)" "unprognostic (2.61e-1)" "unprognostic (9.06e-2)" "unprognostic (4.82e-1)" "unprognostic (5.82e-2)" "unprognostic (2.01e-1)" "unprognostic (2.66e-1)" "unprognostic (3.75e-1)" "unprognostic (2.62e-1)" "unprognostic (2.09e-1)" "unprognostic (1.85e-2)" "unprognostic (1.28e-1)" "unprognostic (4.06e-1)" "unprognostic (1.22e-3)" "unprognostic (4.86e-2)" C11orf54 PTD012 ENSG00000182919 "Chromosome 11 open reading frame 54" Q9H0W9 11 93741591-93764749 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "kidney: 530.1;liver: 241.6" "Cell type enhanced" "Detected in many" "Astrocytes: 49.5;Bergmann glia: 47.3;Brain inhibitory neurons: 38.2;Choroid plexus epithelial cells: 60.4;Ependymal cells: 39.7;Hepatocytes: 108.6;Oligodendrocyte progenitor cells: 53.5;Oligodendrocytes: 47.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 129.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040088, HPA040511" Approved Approved "Nucleoplasm,Nuclear bodies" NA NA 570000 "Cluster 21: Neutrophils - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 30: White matter - Myelination" "Cluster 24: Non-specific - Unknown function" "Cluster 22: Non-specific - Basic cellular functions" 7 "Nuclear bodies" Nucleoplasm "HPA040088: , HPA040511: " "unprognostic (2.01e-2)" "unprognostic (3.85e-2)" "unprognostic (2.13e-1)" "unprognostic (1.62e-2)" "unprognostic (4.49e-2)" "unprognostic (1.32e-1)" "unprognostic (7.57e-2)" "unprognostic (1.68e-1)" "unprognostic (1.13e-1)" "unprognostic (9.72e-2)" "validated prognostic favorable (1.45e-11)" "validated prognostic favorable (5.59e-4)" "unprognostic (1.70e-2)" "unprognostic (4.68e-2)" "unprognostic (3.05e-3)" "unprognostic (7.95e-2)" "unprognostic (3.24e-1)" "unprognostic (2.99e-2)" "unprognostic (1.05e-1)" "unprognostic (2.43e-1)" "unprognostic (1.02e-2)" "unprognostic (5.53e-3)" "unprognostic (1.88e-1)" "unprognostic (3.70e-1)" "potential prognostic favorable (9.51e-5)" "unprognostic (3.30e-1)" "unprognostic (8.00e-2)" "unprognostic (1.99e-1)" "unprognostic (2.33e-1)" "unprognostic (1.96e-1)" "unprognostic (2.45e-1)" C11orf58 SMAP ENSG00000110696 "Chromosome 11 open reading frame 58" O00193 11 16613132-16758340 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036591, HPA076406" Uncertain Approved "Nucleoplasm,Endoplasmic reticulum" NA NA 31000 "Cluster 41: Basophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 1 "Endoplasmic reticulum" Nucleoplasm "HPA036591: , HPA076406: " "unprognostic (6.34e-2)" "unprognostic (2.66e-1)" "unprognostic (5.83e-2)" "unprognostic (4.24e-2)" "unprognostic (2.37e-1)" "unprognostic (6.85e-2)" "unprognostic (1.99e-1)" "unprognostic (1.13e-1)" "unprognostic (1.83e-1)" "potential prognostic unfavorable (9.19e-4)" "validated prognostic favorable (4.07e-9)" "validated prognostic favorable (6.84e-5)" "unprognostic (1.49e-1)" "unprognostic (4.89e-2)" "unprognostic (5.22e-2)" "unprognostic (1.33e-1)" "unprognostic (1.77e-2)" "unprognostic (1.14e-2)" "unprognostic (4.29e-2)" "unprognostic (2.38e-1)" "unprognostic (1.43e-3)" "unprognostic (1.40e-2)" "potential prognostic unfavorable (5.56e-4)" "unprognostic (3.05e-1)" "unprognostic (1.04e-2)" "unprognostic (3.64e-1)" "unprognostic (1.43e-1)" "unprognostic (9.45e-2)" "unprognostic (2.74e-1)" "unprognostic (1.60e-1)" "unprognostic (1.05e-1)" C11orf65 "MFI, MGC33948" ENSG00000166323 "Chromosome 11 open reading frame 65" Q8NCR3 11 108308519-108467531 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "testis: 47.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 194.2;Early primary spermatocytes: 249.9;Early spermatids: 924.9;Epicardial cells: 227.4;Late primary spermatocytes: 678.6" "Cell type enhanced" "Detected in all" "ependymal cell: 119.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Breast - T-cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" NA NA "Cluster 32: Basophils - Transcription" "Cluster 57: Testis - Spermatogenesis" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 8 "unprognostic (5.19e-2)" "unprognostic (3.30e-1)" "unprognostic (7.30e-2)" "unprognostic (8.59e-2)" "potential prognostic favorable (2.81e-4)" "unprognostic (1.15e-2)" "unprognostic (6.11e-2)" "unprognostic (3.77e-1)" "unprognostic (3.36e-2)" "unprognostic (1.29e-2)" "unprognostic (1.41e-1)" "unprognostic (2.42e-1)" C11orf68 "BLES03, P5326" ENSG00000175573 "Chromosome 11 open reading frame 68" Q9H3H3 11 65916810-65919062 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045938 Uncertain Approved "Nucleoplasm,Nucleoli,Nucleoli rim" No Yes "Cluster 35: Neutrophils - Protein binding" "Cluster 24: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 4 "Nucleoplasm, Nucleoli" "Nucleoli rim" "HPA045938: " "unprognostic (1.20e-2)" "unprognostic (4.02e-2)" "unprognostic (4.95e-2)" "unprognostic (3.11e-2)" "unprognostic (3.56e-2)" "unprognostic (1.08e-1)" "unprognostic (1.49e-1)" "unprognostic (1.89e-1)" "unprognostic (2.06e-1)" "unprognostic (8.58e-2)" "potential prognostic favorable (1.95e-5)" "unprognostic (5.07e-2)" "unprognostic (1.13e-2)" "unprognostic (4.28e-3)" "unprognostic (1.98e-1)" "unprognostic (4.38e-2)" "potential prognostic unfavorable (9.93e-4)" "unprognostic (8.85e-2)" "unprognostic (2.10e-1)" "unprognostic (4.56e-2)" "unprognostic (3.82e-2)" "unprognostic (1.31e-1)" "unprognostic (1.49e-1)" "unprognostic (1.42e-3)" "unprognostic (4.24e-2)" "unprognostic (1.35e-1)" "unprognostic (1.14e-1)" "unprognostic (2.35e-1)" "unprognostic (1.38e-1)" "unprognostic (5.44e-2)" "unprognostic (1.28e-2)" C11orf71 FLJ20010 ENSG00000180425 "Chromosome 11 open reading frame 71" Q6IPW1 11 114391443-114400511 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "testis: 130.9" "Cell type enriched" "Detected in many" 5 "Late spermatids: 9403.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063943, HPA074787" Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 79: Testis - Spermatogenesis" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" Nucleoplasm "Nuclear bodies" "HPA063943: , HPA074787: " "unprognostic (1.40e-1)" "unprognostic (1.47e-1)" "unprognostic (3.91e-3)" "unprognostic (7.69e-2)" "unprognostic (1.27e-2)" "unprognostic (2.59e-1)" "unprognostic (3.00e-1)" "unprognostic (3.01e-3)" "unprognostic (6.12e-2)" "unprognostic (3.10e-1)" "potential prognostic favorable (1.11e-6)" "unprognostic (3.33e-3)" "potential prognostic favorable (8.38e-10)" "unprognostic (1.60e-1)" "unprognostic (2.85e-1)" "unprognostic (3.63e-2)" "unprognostic (2.73e-1)" "unprognostic (2.12e-2)" "potential prognostic favorable (9.90e-4)" "unprognostic (1.61e-3)" "unprognostic (1.62e-1)" "unprognostic (1.81e-2)" "unprognostic (1.19e-1)" "unprognostic (2.26e-1)" "unprognostic (2.90e-3)" "unprognostic (3.27e-1)" "unprognostic (6.03e-2)" "unprognostic (1.64e-2)" "unprognostic (1.87e-1)" "unprognostic (8.05e-2)" "unprognostic (3.24e-3)" C11orf80 "FLJ22531, TOPOVIBL" ENSG00000173715 "Chromosome 11 open reading frame 80" Q8N6T0 11 66744451-66843516 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Meiosis "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 260.8;Renal collecting duct intercalated cells: 434.7;Renal collecting duct principal cells: 583.8;Renal connecting tubule cells: 463.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA038932, HPA038933" Approved Approved Centrosome NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 2: Non-specific - Mixed function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 24: Non-specific - Unknown function" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" Centrosome "HPA038932: , HPA038933: " "unprognostic (1.24e-1)" "unprognostic (2.05e-1)" "unprognostic (2.64e-1)" "unprognostic (1.52e-1)" "unprognostic (1.95e-1)" "unprognostic (2.75e-1)" "unprognostic (3.11e-1)" "unprognostic (9.80e-2)" "unprognostic (3.47e-1)" "unprognostic (3.83e-2)" "unprognostic (3.08e-1)" "unprognostic (3.83e-3)" "unprognostic (2.18e-1)" "unprognostic (1.28e-2)" "unprognostic (4.24e-3)" "unprognostic (2.22e-3)" "potential prognostic unfavorable (6.02e-4)" "unprognostic (2.16e-1)" "unprognostic (4.85e-2)" "unprognostic (8.80e-2)" "unprognostic (1.23e-1)" "unprognostic (3.35e-2)" "potential prognostic unfavorable (3.52e-7)" "unprognostic (1.07e-2)" "unprognostic (4.00e-2)" "unprognostic (6.39e-2)" "unprognostic (5.55e-3)" "unprognostic (1.10e-1)" "unprognostic (9.82e-2)" "unprognostic (4.18e-2)" "unprognostic (1.81e-1)" C11orf86 FLJ22675 ENSG00000173237 "Chromosome 11 open reading frame 86" A6NJI1 11 66975277-66977009 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "intestine: 64.8" "Group enriched" "Detected in some" 8 "Colonocytes: 190.4;Enterocytes: 498.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Pancreatic Adenocarcinoma (TCGA): 5.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Adrenocortical cancer: 18.6;cervical cancer: 41.9;Rhabdoid: 12.4" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Colon - Colon enterocytes, Kidney - Proximal tubular cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA039348 Uncertain NA NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 7: Liver cancer - Metabolism" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" "HPA039348: " "unprognostic (5.41e-1)" "unprognostic (3.11e-2)" "unprognostic (1.18e-2)" "unprognostic (2.65e-2)" "unprognostic (9.40e-2)" "potential prognostic unfavorable (6.79e-4)" "potential prognostic unfavorable (1.30e-5)" "unprognostic (1.50e-1)" "unprognostic (7.95e-2)" "unprognostic (2.85e-2)" "unprognostic (1.44e-1)" C11orf87 "LOC399947, LOH11CR1A, NEURIM1" ENSG00000185742 "Chromosome 11 open reading frame 87" Q6NUJ2 11 109422190-109429167 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "brain: 18.0" "Group enriched" "Detected in some" 4 "Brain excitatory neurons: 46.7;Brain inhibitory neurons: 48.4;Other brain neurons: 17.5;Retinal amacrine cells: 20.7;Retinal horizontal cells: 14.0" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in single" "Glioblastoma Multiforme (TCGA): 1.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 23 "Rhabdoid: 14.5" "Pituitary gland - Gonadotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034656 Approved NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 5: Rhabdoid - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" 19 "HPA034656: " "unprognostic (6.05e-2)" "unprognostic (1.53e-1)" C11orf91 ENSG00000205177 "Chromosome 11 open reading frame 91" Q3C1V1 11 33698261-33700826 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 4.4;gallbladder: 4.3;testis: 9.0" "Group enriched" "Detected in some" 5 "Early spermatids: 10.2;Late primary spermatocytes: 25.9" "Cell type enhanced" "Detected in some" "endothelial cell: 2.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047064, HPA050487" Uncertain Supported Vesicles NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 15: Non-specific - Transcription" "Cluster 72: Neuronal - Signal transduction" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" Vesicles "HPA047064: , HPA050487: " "unprognostic (2.90e-2)" "unprognostic (2.29e-1)" "unprognostic (1.05e-1)" "unprognostic (4.51e-3)" "unprognostic (2.26e-2)" C11orf94 Frey ENSG00000234776 "Chromosome 11 open reading frame 94" C9JXX5 11 45906513-45907272 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 158 "testis: 54.9" "Group enriched" "Detected in some" 144 "Early spermatids: 436.4;Late primary spermatocytes: 197.9;Late spermatids: 264.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 56: Non-specific - Sensory perception" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" "potential prognostic favorable (3.22e-5)" C11orf96 AG2 ENSG00000187479 "Chromosome 11 open reading frame 96" 11 43942637-43943878 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "blood vessel: 1697.4" "Group enriched" "Detected in some" 4 "Pericytes: 15.2;Smooth muscle cells: 18.4;Vascular smooth muscle cells: 37.1" "Cell type enriched" "Detected in single" 16 "vascular associated smooth muscle cell: 10.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Neuroblastoma: 48.9" "Adipose subcutaneous - Smooth muscle cells, Breast - Endothelial cells, Colon - Neutrophils" "Low region specificity" "Detected in all" HPA038843 Uncertain Approved "Nucleoplasm,Focal adhesion sites,Cytosol" No NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 44: Non-specific - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 105: Non-specific - Mixed function" "Nucleoplasm, Cytosol" "Focal adhesion sites" "HPA038843: " "unprognostic (2.12e-1)" "unprognostic (2.00e-1)" "unprognostic (3.42e-2)" "unprognostic (3.44e-2)" "unprognostic (4.74e-2)" "unprognostic (4.61e-2)" "unprognostic (1.26e-2)" "unprognostic (2.35e-3)" "unprognostic (1.33e-1)" "unprognostic (2.10e-1)" "unprognostic (2.71e-3)" "unprognostic (5.78e-3)" "unprognostic (1.20e-2)" "potential prognostic favorable (6.20e-4)" "unprognostic (9.74e-2)" "unprognostic (1.10e-1)" "potential prognostic unfavorable (1.05e-4)" "unprognostic (2.86e-1)" "unprognostic (6.31e-2)" "unprognostic (1.83e-1)" "unprognostic (7.70e-2)" "unprognostic (2.66e-1)" "unprognostic (1.16e-2)" "unprognostic (6.81e-2)" "unprognostic (2.68e-3)" "unprognostic (1.58e-2)" "unprognostic (2.08e-2)" "unprognostic (1.07e-1)" "unprognostic (1.74e-3)" "unprognostic (4.32e-2)" C11orf97 LINC01171 ENSG00000257057 "Chromosome 11 open reading frame 97" A0A1B0GVM6 11 94512461-94532123 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "brain: 10.4;choroid plexus: 10.8;fallopian tube: 18.0;testis: 18.2" "Group enriched" "Detected in some" 9 "Early spermatids: 196.6;Endometrial ciliated cells: 255.6;Epididymal efferent duct ciliated cells: 322.3;Fallopian tube ciliated cells: 320.0;Late primary spermatocytes: 269.2;Respiratory ciliated cells: 381.0" "Cell type enhanced" "Detected in many" "ependymal cell: 30.1" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 3.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 18 "lymphoma: 1.7" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 107: Ciliated cells - Cilia assembly & function" "unprognostic (2.95e-3)" "unprognostic (2.13e-1)" "unprognostic (1.66e-1)" C11orf98 C11orf48 ENSG00000278615 "Chromosome 11 open reading frame 98" E9PRG8 11 62662817-62665210 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial secretory cells: 4.9;Hepatocytes: 9.8;Lacrimal acinar cells: 4.5;Megakaryocytes: 12.4;Oocytes: 4.6;Parietal cells: 8.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 3 "unprognostic (1.80e-1)" "unprognostic (2.88e-1)" "unprognostic (1.00e-1)" "unprognostic (4.52e-2)" "unprognostic (7.01e-2)" "unprognostic (2.00e-1)" "unprognostic (3.01e-2)" "unprognostic (2.70e-2)" "validated prognostic unfavorable (3.78e-5)" "validated prognostic unfavorable (2.72e-4)" "unprognostic (6.03e-2)" "potential prognostic unfavorable (3.63e-4)" "unprognostic (1.60e-2)" "unprognostic (7.97e-3)" "unprognostic (8.08e-2)" "unprognostic (1.56e-1)" "unprognostic (3.27e-2)" "potential prognostic unfavorable (4.25e-4)" "unprognostic (3.29e-1)" "unprognostic (4.16e-1)" "unprognostic (9.25e-2)" "unprognostic (1.14e-1)" "unprognostic (5.83e-3)" "unprognostic (1.12e-1)" "unprognostic (7.80e-2)" "unprognostic (2.53e-2)" C12orf29 DKFZp434N2030 ENSG00000133641 "Chromosome 12 open reading frame 29" Q8N999 12 88033846-88050160 "Predicted intracellular proteins" "RNA repair" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 459.9;Esophageal suprabasal cells: 119.5;Oocytes: 156.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039663 Uncertain Approved Vesicles NA NA "Cluster 24: Non-specific - Transcription" "Cluster 55: Breast - Lactation" "Cluster 34: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 84: Apical squamous epithelium - Cornification" Vesicles "HPA039663: " "unprognostic (1.20e-2)" "unprognostic (2.44e-2)" "unprognostic (3.00e-3)" "unprognostic (1.93e-3)" "unprognostic (2.17e-2)" "unprognostic (1.83e-1)" "unprognostic (4.86e-2)" "unprognostic (2.61e-1)" "unprognostic (2.09e-1)" "unprognostic (5.34e-3)" "potential prognostic favorable (2.24e-4)" "unprognostic (2.21e-1)" "unprognostic (1.88e-3)" "unprognostic (7.00e-3)" "unprognostic (4.99e-2)" "unprognostic (1.05e-3)" "unprognostic (3.53e-2)" "unprognostic (3.02e-2)" "unprognostic (1.67e-1)" "unprognostic (6.83e-2)" "potential prognostic unfavorable (5.46e-4)" "unprognostic (1.70e-1)" "unprognostic (3.26e-2)" "unprognostic (2.07e-2)" "unprognostic (1.91e-2)" "unprognostic (5.38e-2)" "unprognostic (3.92e-1)" "unprognostic (1.38e-1)" "unprognostic (2.33e-1)" "unprognostic (4.79e-2)" "unprognostic (3.54e-2)" C12orf4 ENSG00000047621 "Chromosome 12 open reading frame 4" Q9NQ89 12 4487735-4538508 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037871 Uncertain Approved "Nuclear bodies" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 9 "Nuclear bodies" "HPA037871: " "unprognostic (2.24e-2)" "unprognostic (7.33e-2)" "unprognostic (5.71e-3)" "unprognostic (1.96e-1)" "unprognostic (4.38e-2)" "unprognostic (1.55e-1)" "unprognostic (8.09e-2)" "unprognostic (3.58e-3)" "unprognostic (3.50e-2)" "potential prognostic unfavorable (4.87e-5)" "potential prognostic favorable (1.78e-4)" "unprognostic (1.79e-1)" "unprognostic (1.47e-1)" "potential prognostic unfavorable (2.26e-4)" "unprognostic (8.53e-2)" "unprognostic (2.10e-1)" "unprognostic (4.97e-2)" "unprognostic (2.11e-2)" "unprognostic (1.98e-2)" "unprognostic (3.65e-3)" "unprognostic (3.68e-2)" "unprognostic (1.07e-1)" "potential prognostic unfavorable (2.44e-4)" "unprognostic (3.06e-1)" "unprognostic (2.52e-2)" "unprognostic (1.44e-2)" "unprognostic (6.35e-2)" "unprognostic (4.72e-2)" "unprognostic (3.70e-1)" "unprognostic (3.29e-2)" "unprognostic (6.82e-2)" C12orf40 FLJ40126 ENSG00000180116 "Chromosome 12 open reading frame 40" Q86WS4 12 39626167-39908300 "Predicted intracellular proteins" Meiosis "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 31 "testis: 8.2" "Cell type enhanced" "Detected in many" "Adipocytes: 55.6;Cardiomyocytes: 205.2;Early primary spermatocytes: 73.1;Epicardial cells: 81.9;Fibro-adipogenic progenitors: 69.5;Late primary spermatocytes: 71.9;Other brain neurons: 53.6;Retinal ganglion cells: 77.3;Retinal horizontal cells: 118.2" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in single" 13 "Testicular Germ Cell Tumor (TCGA): 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Spermatocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA039032 Approved "Golgi apparatus,Cytosol" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 47: Leukemia - Hemostasis" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 4 "Golgi apparatus" Cytosol "HPA039032: " "unprognostic (3.55e-1)" C12orf42 FLJ25323 ENSG00000179088 "Chromosome 12 open reading frame 42" Q96LP6 12 103237591-103495978 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 13 "testis: 16.2" "Cell type enhanced" "Detected in many" "B-cells: 198.1;Breast lactating cells: 120.2;Early spermatids: 507.0;Late primary spermatocytes: 254.8;Late spermatids: 537.9;Microglia: 72.5" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 85.1" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "memory B-cell: 5.2;naive B-cell: 5.3" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Pituitary gland - Corticotropes, Spleen - B-cells (Spleen), Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - T-cells" "Not detected" "Not detected" NA NA "Cluster 18: Non-specific - Translation" "Cluster 39: Testis - Nuclear processes" "Cluster 51: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 87: B-cells - Adaptive immunity: Humoral response" C12orf43 "Custos, FLJ12448" ENSG00000157895 "Chromosome 12 open reading frame 43" Q96C57 12 121000486-121016502 "Predicted intracellular proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046148, HPA061739" Uncertain Supported "Nucleoli,Golgi apparatus" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 73: Brain - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 20: Non-specific - Transcription regulation" 11 Nucleoli "Golgi apparatus" "HPA046148: , HPA061739: " "unprognostic (1.54e-2)" "unprognostic (2.33e-1)" "potential prognostic unfavorable (2.19e-4)" "unprognostic (2.32e-1)" "unprognostic (4.50e-2)" "unprognostic (1.95e-1)" "unprognostic (1.50e-1)" "potential prognostic favorable (2.33e-4)" "unprognostic (8.58e-2)" "unprognostic (6.03e-2)" "validated prognostic favorable (3.00e-7)" "validated prognostic favorable (1.49e-4)" "unprognostic (4.42e-3)" "potential prognostic unfavorable (1.80e-4)" "unprognostic (5.14e-3)" "unprognostic (1.87e-2)" "unprognostic (1.83e-1)" "unprognostic (6.84e-2)" "unprognostic (9.65e-3)" "unprognostic (2.96e-1)" "unprognostic (9.22e-3)" "unprognostic (4.61e-1)" "unprognostic (4.30e-3)" "unprognostic (1.44e-1)" "unprognostic (1.89e-1)" "unprognostic (2.26e-1)" "unprognostic (1.66e-2)" "unprognostic (1.88e-1)" "unprognostic (1.01e-1)" "unprognostic (2.15e-1)" "potential prognostic favorable (7.41e-4)" C12orf50 FLJ35821 ENSG00000165805 "Chromosome 12 open reading frame 50" Q8NA57 12 87980035-88034037 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 473 "testis: 47.2" "Cell type enhanced" "Detected in some" "Early spermatids: 903.7;Late primary spermatocytes: 412.1;Late spermatids: 2082.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 2 "unprognostic (6.47e-3)" "unprognostic (7.40e-3)" C12orf54 MGC35033 ENSG00000177627 "Chromosome 12 open reading frame 54" Q6X4T0 12 48482498-48496524 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 79 "testis: 49.9" "Cell type enriched" "Detected in some" 6 "Late spermatids: 4342.9" "Low cell type specificity" "Detected in some" "Group enriched" "Detected in some" 5 "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 1.0;Head and Neck Squamous Cell Carcinoma (TCGA): 1.2;Lung Squamous Cell Carcinoma (TCGA): 1.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 2.2;Gallbladder cancer: 3.4;head and neck cancer: 1.9" "Testis - Late spermatids" "Not detected" "Not detected" "HPA039919, HPA073090" Supported "Intermediate filaments,Cytosol" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 24: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" "Intermediate filaments" Cytosol "HPA039919: , HPA073090: " "unprognostic (2.91e-1)" "unprognostic (1.38e-1)" "unprognostic (5.71e-2)" "unprognostic (1.37e-1)" C12orf56 ENSG00000185306 "Chromosome 12 open reading frame 56" Q8IXR9 12 64264762-64390758 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "choroid plexus: 2.3;testis: 7.0" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 170.2;Early spermatids: 64.2;Esophageal apical cells: 109.2;Late primary spermatocytes: 58.2;Late spermatids: 57.8;Müller glia: 83.7;Podocytes: 51.4" "Cell type enriched" "Detected in many" 7 "choroid plexus epithelial cell: 209.9" "Cancer enhanced" "Detected in some" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 1.5" "Region enhanced" "Detected in all" "choroid plexus: 15.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 1.3;thyroid cancer: 1.4" "Kidney - Podocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA056986 Enhanced NA NA "Cluster 39: Testis - Nuclear processes" "Cluster 36: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" "HPA056986: " "unprognostic (2.07e-1)" "potential prognostic favorable (6.66e-5)" "unprognostic (3.39e-3)" "unprognostic (8.55e-3)" "unprognostic (3.31e-2)" "unprognostic (6.20e-2)" "unprognostic (2.17e-2)" C12orf57 "C10, GRCC10" ENSG00000111678 "Chromosome 12 open reading frame 57" Q99622 12 6942978-6946003 "Disease related genes, Predicted intracellular proteins" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cell type enhanced" "Detected in all" "pericyte: 118.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046182, HPA059163, HPA066043" Approved Enhanced "Nuclear speckles" NA NA 6100 "Cluster 5: Non-specific - Cell proliferation" "Cluster 54: Non-specific - Ribosome" "Cluster 21: Non-specific - Metabolism" "Cluster 35: RS4;11 - Unknown function" "Cluster 62: Smooth muscle cells - Muscle contraction" 19 "Nuclear speckles" "HPA046182: , HPA059163: , HPA066043: " "unprognostic (8.94e-3)" "unprognostic (1.25e-1)" "unprognostic (3.14e-1)" "unprognostic (1.19e-3)" "unprognostic (7.57e-2)" "unprognostic (3.12e-2)" "unprognostic (6.20e-2)" "unprognostic (2.96e-1)" "unprognostic (3.43e-1)" "unprognostic (6.04e-2)" "unprognostic (3.93e-3)" "unprognostic (1.20e-1)" "unprognostic (7.43e-2)" "unprognostic (7.95e-3)" "unprognostic (4.47e-3)" "unprognostic (4.61e-2)" "unprognostic (1.93e-1)" "unprognostic (1.85e-1)" "unprognostic (2.57e-1)" "unprognostic (8.06e-2)" "unprognostic (7.35e-2)" "unprognostic (1.56e-3)" "unprognostic (7.70e-2)" "unprognostic (1.18e-2)" "unprognostic (9.05e-3)" "unprognostic (5.71e-2)" "unprognostic (9.94e-2)" "unprognostic (8.25e-2)" "unprognostic (3.25e-1)" "unprognostic (4.09e-2)" "unprognostic (3.27e-2)" C12orf60 MGC47869 ENSG00000182993 "Chromosome 12 open reading frame 60" Q5U649 12 14803666-14906586 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 14.5" "Cell type enhanced" "Detected in many" "Early spermatids: 577.0;Fibro-adipogenic progenitors: 101.1;Fibroblasts: 173.8;Late primary spermatocytes: 293.4;Late spermatids: 104.8;Vascular endothelial cells: 74.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA042461, HPA043911" Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 47: Testis - Mixed function" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 47: Leukemia - Hemostasis" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 1 Cytosol "Nucleoplasm, Vesicles, Plasma membrane" "HPA042461: , HPA043911: " "unprognostic (1.09e-1)" "unprognostic (3.12e-1)" "unprognostic (2.61e-3)" "unprognostic (1.96e-1)" "unprognostic (1.14e-1)" "unprognostic (2.43e-2)" "unprognostic (6.80e-3)" "unprognostic (2.10e-2)" "unprognostic (1.56e-1)" "unprognostic (2.07e-1)" "unprognostic (6.46e-3)" "unprognostic (2.90e-1)" "unprognostic (3.58e-2)" "unprognostic (2.74e-1)" "unprognostic (1.59e-1)" "unprognostic (7.37e-2)" "unprognostic (1.37e-1)" "unprognostic (6.29e-3)" "unprognostic (5.05e-2)" "unprognostic (1.11e-1)" "unprognostic (2.83e-1)" "unprognostic (1.82e-1)" C12orf71 LOC728858 ENSG00000214700 "Chromosome 12 open reading frame 71" A8MTZ7 12 27081057-27082578 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 1.3;testis: 2.9" "Group enriched" "Detected in some" 7 "Early spermatids: 10.6;Late primary spermatocytes: 27.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 10 "NK-cell: 1.0" "Lineage enriched" "Detected in single" 10 "NK-cells: 1.0" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "HPA038359, HPA058728" Uncertain Approved Cytosol NA NA "Cluster 47: Testis - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 56: Non-specific - Sensory perception" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" Cytosol "HPA038359: , HPA058728: " C12orf73 "BRAWNIN, DKFZp547P055, FLJ13975" ENSG00000204954 "Chromosome 12 open reading frame 73" Q69YU5 12 103940763-103965708 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 39.9" "Cell type enriched" "Detected in many" 6 "Epicardial cells: 734.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038883 Uncertain Approved "Plasma membrane,Centrosome,Mitochondria" "Intracellular and membrane" "No annotated function" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 31: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 3 "Centrosome, Mitochondria" "Plasma membrane" "HPA038883: " "unprognostic (6.62e-3)" "unprognostic (1.97e-2)" "unprognostic (7.40e-3)" "unprognostic (1.43e-1)" "unprognostic (3.15e-2)" "unprognostic (2.58e-1)" "unprognostic (3.45e-2)" "unprognostic (8.23e-3)" "unprognostic (4.51e-1)" "potential prognostic unfavorable (2.37e-5)" "unprognostic (1.55e-3)" "potential prognostic unfavorable (4.06e-4)" "unprognostic (7.54e-2)" "unprognostic (1.62e-3)" "potential prognostic unfavorable (1.51e-6)" "unprognostic (1.90e-2)" "unprognostic (4.42e-3)" "unprognostic (1.56e-2)" "unprognostic (6.32e-2)" "unprognostic (1.44e-1)" "unprognostic (2.00e-2)" "unprognostic (5.77e-3)" "unprognostic (6.86e-3)" "unprognostic (8.48e-2)" "unprognostic (3.98e-2)" "unprognostic (3.67e-1)" "unprognostic (1.75e-2)" "unprognostic (2.22e-1)" "unprognostic (1.20e-1)" "unprognostic (2.31e-2)" "unprognostic (8.60e-2)" C12orf75 "AGD3, OCC-1, OCC1" ENSG00000235162 "Chromosome 12 open reading frame 75" Q8TAD7 12 105235290-105396097 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 129.2;seminal vesicle: 102.9" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 692.7;Epididymal clear cells: 1102.3;Extravillous trophoblasts: 1968.3;Gastric progenitor cells: 557.5;Late spermatids: 518.5;Megakaryocytes: 1224.0;Parietal cells: 716.0;pDCs: 983.7;Respiratory ciliated cells: 536.5" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 213.7" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 229.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 664.5" "Group enriched" "Detected in all" 6 "dendritic cells: 664.5;T-cells: 170.1" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal cortex cells, Breast - Fibroblasts, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Spleen - Mitotic cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065311 Uncertain Approved Vesicles NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 3 Vesicles "HPA065311: " "unprognostic (1.32e-1)" "unprognostic (3.52e-2)" "unprognostic (9.40e-2)" "unprognostic (2.39e-1)" "unprognostic (3.52e-1)" "unprognostic (3.81e-2)" "unprognostic (8.61e-3)" "unprognostic (2.32e-1)" "unprognostic (1.58e-1)" "unprognostic (8.58e-2)" "potential prognostic favorable (1.83e-4)" "unprognostic (7.76e-3)" "unprognostic (5.05e-3)" "unprognostic (1.21e-3)" "unprognostic (4.60e-3)" "unprognostic (1.59e-1)" "unprognostic (6.83e-2)" "unprognostic (2.27e-2)" "unprognostic (1.66e-2)" "unprognostic (1.27e-1)" "unprognostic (4.81e-1)" "unprognostic (3.44e-1)" "unprognostic (2.04e-1)" "unprognostic (1.43e-1)" "unprognostic (6.45e-2)" "unprognostic (5.85e-3)" "unprognostic (4.58e-2)" "unprognostic (2.82e-3)" "unprognostic (1.18e-1)" "unprognostic (5.68e-2)" "unprognostic (2.06e-1)" C12orf76 FLJ40142 ENSG00000174456 "Chromosome 12 open reading frame 76" 12 110027028-110073636 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 39.2" "Cell type enriched" "Detected in many" 4 "Platelets: 415.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 46.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 47: Platelets - Hemostasis" "unprognostic (8.82e-2)" "unprognostic (1.58e-1)" "unprognostic (2.73e-1)" "unprognostic (2.33e-1)" "unprognostic (1.73e-3)" "unprognostic (1.05e-2)" "unprognostic (4.44e-2)" "unprognostic (5.93e-3)" "unprognostic (8.94e-2)" "unprognostic (2.63e-1)" "unprognostic (2.07e-1)" "unprognostic (3.54e-1)" "unprognostic (4.33e-2)" "potential prognostic unfavorable (8.30e-4)" "unprognostic (2.62e-3)" "potential prognostic favorable (3.30e-4)" "unprognostic (2.99e-1)" "unprognostic (1.02e-1)" "unprognostic (2.02e-2)" "unprognostic (1.07e-1)" "unprognostic (1.51e-2)" "unprognostic (5.87e-3)" "potential prognostic unfavorable (8.24e-4)" "unprognostic (1.49e-1)" "unprognostic (3.29e-2)" "unprognostic (3.91e-1)" "unprognostic (4.28e-2)" "unprognostic (5.15e-2)" "unprognostic (1.93e-1)" "unprognostic (1.66e-1)" "unprognostic (3.63e-2)" C13orf42 LINC00371 ENSG00000226792 "Chromosome 13 open reading frame 42" A0A1B0GVH6 13 51082119-51200252 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Early spermatids: 29.1;Late primary spermatocytes: 23.1;Late spermatids: 13.0;Oocytes: 9.2;Thymic myoid cells: 9.5;Undifferentiated spermatogonia: 15.6" "Cell type enhanced" "Detected in some" "hippocampal CA1-3: 4.4" "Cancer enriched" "Detected in single" 20 "Testicular Germ Cell Tumor (TCGA): 1.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 23 "testis cancer: 2.3" "Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 34: Testis cancer - Unknown function" "Cluster 46: Skeletal myocytes - Muscle structure & formation" "unprognostic (5.30e-2)" "unprognostic (8.59e-3)" C13orf46 ENSG00000283199 "Chromosome 13 open reading frame 46" A0A1B0GUA9 13 113953705-113974076 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "pancreas: 8.7;stomach 1: 6.1;testis: 11.8" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 3.0;Early spermatids: 11.0;Ependymal cells: 2.3;Late primary spermatocytes: 4.6;Late spermatids: 24.5;Microglia: 2.9" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 4.4;leukocyte: 4.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 21: Testis - Mixed function" "Cluster 8: Immune cells - Immune response" "Cluster 72: Neuronal - Signal transduction" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" C14orf119 FLJ20671 ENSG00000179933 "Chromosome 14 open reading frame 119" Q9NWQ9 14 23095505-23100456 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 189.0;Syncytiotrophoblasts: 190.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003638 Uncertain Supported Mitochondria,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 22: Epididymis - Mixed function" "Cluster 45: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 97: Non-specific - Cellular respiration" 48 Mitochondria Cytosol "HPA003638: " "unprognostic (2.66e-1)" "unprognostic (1.39e-1)" "unprognostic (8.36e-3)" "unprognostic (1.27e-1)" "unprognostic (2.12e-2)" "unprognostic (3.35e-2)" "unprognostic (1.08e-1)" "unprognostic (1.57e-1)" "unprognostic (1.25e-3)" "unprognostic (9.29e-2)" "potential prognostic favorable (1.36e-6)" "unprognostic (5.02e-2)" "unprognostic (1.88e-1)" "validated prognostic unfavorable (6.14e-7)" "validated prognostic unfavorable (3.89e-4)" "unprognostic (8.23e-2)" "unprognostic (3.40e-3)" "unprognostic (5.33e-3)" "unprognostic (1.53e-1)" "unprognostic (3.18e-1)" "unprognostic (2.71e-1)" "potential prognostic unfavorable (1.88e-4)" "unprognostic (8.32e-2)" "unprognostic (2.17e-1)" "unprognostic (1.07e-1)" "unprognostic (8.17e-2)" "unprognostic (2.40e-1)" "unprognostic (4.18e-2)" "unprognostic (1.05e-2)" "unprognostic (1.38e-2)" "unprognostic (3.92e-1)" C14orf132 C14orf88 ENSG00000227051 "Chromosome 14 open reading frame 132" Q9NPU4 14 96039362-96093971 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 107.7" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 74.5;Alveolar cells type 1: 117.6;Alveolar cells type 2: 60.8;Bergmann glia: 65.2;Brain excitatory neurons: 59.0;Endometrial ciliated cells: 66.7;Fallopian tube ciliated cells: 121.5;Lactotrophs: 108.9;Pancreatic islet cells: 72.1;Somatotrophs: 106.6;Thyrotrophs: 73.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 21.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Neuroblastoma: 64.1" "Adrenal gland - Adrenal medulla cells, Breast - Fibroblasts, Prostate - Fibroblasts, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 29: Forebrain - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" "unprognostic (1.48e-1)" "unprognostic (1.87e-1)" "unprognostic (3.84e-2)" "unprognostic (1.61e-1)" "unprognostic (3.08e-2)" "unprognostic (5.53e-2)" "unprognostic (2.19e-1)" "unprognostic (3.72e-2)" "unprognostic (1.02e-1)" "unprognostic (8.01e-2)" "unprognostic (8.61e-3)" "unprognostic (5.40e-2)" "potential prognostic unfavorable (5.66e-4)" "unprognostic (3.44e-3)" "unprognostic (7.61e-2)" "unprognostic (2.14e-2)" "unprognostic (1.94e-1)" "unprognostic (2.22e-1)" "unprognostic (7.10e-2)" "unprognostic (1.16e-1)" "unprognostic (1.15e-1)" "unprognostic (4.31e-3)" "unprognostic (2.92e-1)" "unprognostic (2.67e-2)" "unprognostic (1.04e-2)" "unprognostic (1.55e-2)" "unprognostic (1.18e-1)" "unprognostic (8.60e-3)" "unprognostic (9.18e-2)" "unprognostic (2.31e-1)" C14orf180 "C14orf77, NRAC" ENSG00000184601 "Chromosome 14 open reading frame 180" Q8N912 14 104579764-104590515 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 38.7;choroid plexus: 41.4;heart muscle: 103.1" "Cell type enhanced" "Detected in some" "Adipocytes: 2.9;Cardiomyocytes: 8.2;Choroid plexus epithelial cells: 42.9;Ependymal cells: 12.1;Gastric chief cells: 2.2" "Cell type enriched" "Detected in some" 5 "choroid plexus epithelial cell: 99.9" "Cancer enhanced" "Detected in single" "Kidney Renal Clear Cell Carcinoma (TCGA): 1.5" "Region enriched" "Detected in many" 8 "choroid plexus: 29.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Minor Salivary Gland - Adipocytes (Minor salivary gland), Pituitary gland - Corticotropes, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Skin - Adipocytes (Skin)" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 36: Choroid plexus - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 38 "potential prognostic favorable (1.47e-4)" "potential prognostic favorable (7.03e-5)" "unprognostic (4.13e-3)" C14orf28 "DRIP-1, DRIP1" ENSG00000179476 "Chromosome 14 open reading frame 28" Q4W4Y0 14 44897275-44907257 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Early spermatids: 179.1;Late primary spermatocytes: 86.2;Late spermatids: 175.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059635 Approved Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 57: Testis - Spermatogenesis" "Cluster 30: White matter - Myelination" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" Cytosol "HPA059635: " "unprognostic (4.35e-2)" "unprognostic (1.46e-1)" "unprognostic (5.63e-2)" "unprognostic (1.39e-2)" "unprognostic (4.29e-1)" "unprognostic (2.04e-1)" "unprognostic (3.87e-1)" "unprognostic (1.45e-1)" "unprognostic (1.73e-1)" "unprognostic (2.07e-1)" "potential prognostic favorable (2.38e-4)" "unprognostic (1.83e-2)" "unprognostic (8.22e-2)" "unprognostic (1.82e-1)" "unprognostic (1.18e-3)" "unprognostic (2.13e-1)" "unprognostic (5.77e-2)" "unprognostic (4.19e-1)" "unprognostic (7.80e-2)" "unprognostic (3.73e-1)" "unprognostic (9.49e-2)" "unprognostic (7.64e-2)" "unprognostic (1.76e-1)" "unprognostic (4.75e-2)" "unprognostic (3.16e-2)" "unprognostic (4.00e-2)" "unprognostic (1.47e-1)" "unprognostic (2.76e-2)" "unprognostic (1.82e-1)" "unprognostic (2.72e-1)" "unprognostic (5.86e-2)" C14orf39 SIX6OS1 ENSG00000179008 "Chromosome 14 open reading frame 39" Q8N1H7 14 60396469-60515543 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, DNA recombination, Meiosis, Spermatogenesis" "Developmental protein" "Disease variant, Premature ovarian failure" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "pituitary gland: 4.5;salivary gland: 4.4;testis: 10.1" "Cell type enhanced" "Detected in many" "Adipocytes: 69.4;Adrenal medulla cells: 63.8;Corticotrophs: 118.8;Early primary spermatocytes: 247.8;Gonadotrophs: 103.2;Lactotrophs: 216.5;Müller glia: 66.2;Myonuclei: 188.3;Pituitary stem cells: 171.9;Somatotrophs: 132.2;Thyrotrophs: 202.6" "Cell type enhanced" "Detected in many" "mammillary body: 46.6" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 1.1" "Group enriched" "Detected in some" 10 "choroid plexus: 1.9;hypothalamus: 6.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 6.0" "Adrenal gland - Adrenal medulla cells, Lung - Respiratory ciliated cells, Testis - Spermatocytes" "Low region specificity" "Detected in many" "Region enhanced" "Detected in single" "hypothalamus: 1.0" HPA059518 Uncertain Approved Nucleoplasm,Nucleoli Yes No "Cluster 47: Testis - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 59: Leukemia - T-cell receptor" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 3 "Nucleoplasm, Nucleoli" "HPA059518: " "unprognostic (1.05e-3)" "unprognostic (1.18e-1)" "unprognostic (3.77e-1)" C14orf93 "FLJ12154, RTFC" ENSG00000100802 "Chromosome 14 open reading frame 93" Q9H972 14 22985894-23010166 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002569 Approved Approved "Nucleoplasm,Plasma membrane" "Secreted to blood" "No annotated function" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 54: Non-specific - Ribosome" "Cluster 46: Brainstem - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" 4 "Nucleoplasm, Plasma membrane" "HPA002569: " "unprognostic (1.66e-1)" "unprognostic (2.40e-2)" "unprognostic (3.78e-1)" "unprognostic (2.01e-2)" "unprognostic (1.28e-1)" "unprognostic (1.15e-1)" "unprognostic (1.05e-3)" "potential prognostic favorable (6.02e-5)" "unprognostic (1.10e-1)" "unprognostic (1.23e-1)" "unprognostic (1.67e-3)" "potential prognostic favorable (2.91e-4)" "unprognostic (7.43e-3)" "unprognostic (4.71e-3)" "unprognostic (5.23e-2)" "unprognostic (1.47e-1)" "unprognostic (1.62e-2)" "unprognostic (3.02e-2)" "unprognostic (5.54e-2)" "unprognostic (1.03e-1)" "unprognostic (1.57e-1)" "unprognostic (7.93e-2)" "unprognostic (2.45e-1)" "unprognostic (1.18e-1)" "unprognostic (2.40e-2)" "unprognostic (7.84e-2)" "unprognostic (1.98e-2)" "unprognostic (2.18e-1)" "unprognostic (2.52e-1)" "unprognostic (4.84e-2)" "unprognostic (5.45e-2)" C15orf39 "DKFZP434H132, FLJ46337" ENSG00000167173 "Chromosome 15 open reading frame 39" Q6ZRI6 15 75195643-75212169 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 58.4;testis: 69.4" "Cell type enhanced" "Detected in many" "Early spermatids: 53.8;Esophageal apical cells: 49.8;Late primary spermatocytes: 87.7;Late spermatids: 144.8;Neutrophils: 118.7" "Cell type enhanced" "Detected in many" "leukocyte: 13.4;pericyte: 13.6;vascular associated smooth muscle cell: 14.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 5 "dendritic cells: 8.1;granulocytes: 23.6;monocytes: 16.3" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039961, HPA041907" Enhanced Enhanced Cytosol NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 46: Brainstem - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 2 Cytosol "HPA039961: , HPA041907: " "unprognostic (7.23e-3)" "unprognostic (1.88e-2)" "unprognostic (3.18e-1)" "unprognostic (7.59e-2)" "unprognostic (3.69e-1)" "unprognostic (7.85e-2)" "unprognostic (6.58e-2)" "unprognostic (2.02e-2)" "unprognostic (2.45e-1)" "unprognostic (4.53e-2)" "potential prognostic favorable (2.42e-4)" "unprognostic (4.50e-3)" "unprognostic (1.26e-1)" "unprognostic (5.35e-2)" "unprognostic (8.00e-3)" "unprognostic (5.53e-2)" "potential prognostic unfavorable (4.27e-4)" "unprognostic (3.04e-2)" "unprognostic (1.97e-2)" "unprognostic (1.57e-1)" "unprognostic (1.19e-1)" "unprognostic (1.14e-1)" "unprognostic (4.35e-2)" "unprognostic (4.06e-2)" "unprognostic (1.07e-1)" "unprognostic (1.37e-1)" "unprognostic (5.63e-3)" "unprognostic (7.06e-2)" "unprognostic (1.22e-1)" "unprognostic (6.04e-2)" "unprognostic (2.47e-1)" C15orf40 MGC29937 ENSG00000169609 "Chromosome 15 open reading frame 40" Q8WUR7 15 82988441-83011641 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041947, HPA042980" Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 48: Non-specific - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 97: Non-specific - Cellular respiration" "Nucleoplasm, Golgi apparatus" "HPA041947: , HPA042980: " "unprognostic (4.77e-2)" "unprognostic (1.00e-1)" "unprognostic (8.35e-2)" "unprognostic (3.04e-1)" "unprognostic (1.78e-1)" "unprognostic (4.06e-3)" "unprognostic (3.04e-1)" "unprognostic (1.29e-2)" "unprognostic (1.01e-1)" "unprognostic (9.89e-3)" "potential prognostic favorable (2.20e-5)" "unprognostic (3.51e-3)" "unprognostic (1.82e-2)" "unprognostic (1.15e-1)" "potential prognostic unfavorable (6.00e-4)" "unprognostic (2.74e-2)" "unprognostic (5.36e-2)" "unprognostic (7.85e-3)" "unprognostic (1.61e-2)" "unprognostic (2.80e-1)" "unprognostic (3.89e-2)" "unprognostic (1.44e-1)" "unprognostic (6.80e-2)" "unprognostic (4.33e-1)" "unprognostic (5.98e-2)" "unprognostic (3.35e-1)" "unprognostic (1.02e-1)" "unprognostic (2.61e-1)" "unprognostic (1.52e-1)" "unprognostic (2.30e-1)" "unprognostic (2.38e-1)" C15orf48 "COXFA4L3, MIR147BHG, MISTRAV, MOCCI, NMES1" ENSG00000166920 "Chromosome 15 open reading frame 48" Q9C002 15 45430579-45448761 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "intestine: 866.5" "Cell type enhanced" "Detected in many" "cDC: 769.7;Colonocytes: 3918.2;Enteric stem cells: 1312.7;Enteric transient amplifying cells: 2389.2;Enterocytes: 2603.8;Esophageal apical cells: 5880.7;Extravillous trophoblasts: 786.5;Goblet cells: 1329.8;Late primary spermatocytes: 1075.0;Pancreatic acinar cells: 1096.3" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "cerebral cortex: 6.3" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.3;intermediate monocyte: 1.6;myeloid DC: 1.3" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 606.0" "Colon - Colon enterocytes, Stomach - Gastric mucous cells, Testis - Early spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA012943 Enhanced NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 17: Intestine - Digestion" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 4 "HPA012943: " "unprognostic (1.86e-1)" "unprognostic (7.97e-3)" "unprognostic (4.28e-2)" "unprognostic (1.11e-1)" "unprognostic (2.29e-1)" "unprognostic (1.11e-2)" "unprognostic (8.26e-3)" "unprognostic (1.32e-1)" "unprognostic (2.37e-2)" "unprognostic (2.00e-1)" "unprognostic (5.20e-2)" "unprognostic (6.91e-3)" "unprognostic (2.02e-1)" "unprognostic (2.05e-3)" "unprognostic (5.89e-3)" "unprognostic (1.81e-3)" "unprognostic (2.40e-3)" "unprognostic (4.93e-2)" "unprognostic (3.13e-2)" "unprognostic (1.14e-1)" "unprognostic (1.87e-1)" "unprognostic (2.67e-3)" "unprognostic (7.08e-2)" "unprognostic (1.08e-2)" "unprognostic (1.57e-1)" "unprognostic (7.14e-3)" "unprognostic (9.66e-2)" "unprognostic (1.03e-1)" "unprognostic (5.02e-2)" "unprognostic (1.47e-1)" "unprognostic (1.95e-1)" C15orf61 LOC145853 ENSG00000189227 "Chromosome 15 open reading frame 61" A6NNL5 15 67521131-67530146 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 22.2" "Group enriched" "Detected in many" 4 "Early spermatids: 174.3;Late primary spermatocytes: 546.9;Oocytes: 414.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062820 Approved Nucleoli,Vesicles,Cytosol "Secreted - unknown location" "No annotated function" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 15: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" "Nucleoli, Vesicles" Cytosol "HPA062820: " "unprognostic (8.62e-3)" "unprognostic (4.12e-2)" "unprognostic (2.89e-2)" "unprognostic (3.21e-2)" "unprognostic (2.61e-1)" "unprognostic (3.15e-1)" "unprognostic (3.30e-1)" "unprognostic (2.35e-2)" "unprognostic (1.34e-1)" "unprognostic (1.09e-2)" "potential prognostic favorable (1.24e-4)" "unprognostic (1.89e-2)" "unprognostic (1.29e-1)" "unprognostic (1.32e-1)" "potential prognostic unfavorable (2.31e-4)" "unprognostic (5.88e-2)" "unprognostic (1.90e-1)" "unprognostic (2.26e-3)" "unprognostic (1.14e-2)" "unprognostic (4.86e-3)" "unprognostic (2.37e-1)" "unprognostic (1.00e-1)" "unprognostic (1.84e-1)" "unprognostic (3.64e-1)" "unprognostic (1.53e-1)" "unprognostic (6.17e-2)" "unprognostic (2.85e-1)" "unprognostic (2.93e-1)" "unprognostic (1.41e-1)" "unprognostic (1.75e-2)" "unprognostic (1.59e-1)" C15orf62 LOC643338 ENSG00000188277 "Chromosome 15 open reading frame 62" A8K5M9 15 40769980-40772449 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 25.4;skin 1: 16.6" "Cell type enriched" "Detected in some" 22 "Esophageal apical cells: 283.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Urothelial cells" "Region enriched" "Detected in single" 5 "olfactory bulb: 1.2" "Not detected" "Not detected" HPA044636 Approved NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 15: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 84: Apical squamous epithelium - Cornification" "HPA044636: " "unprognostic (7.23e-2)" "unprognostic (1.33e-2)" "unprognostic (5.81e-2)" "unprognostic (1.12e-1)" "unprognostic (1.24e-2)" "unprognostic (4.17e-2)" "unprognostic (1.22e-2)" "unprognostic (1.23e-1)" "unprognostic (1.04e-1)" "unprognostic (1.13e-1)" "unprognostic (1.42e-1)" "unprognostic (6.67e-2)" "unprognostic (1.14e-1)" "unprognostic (1.08e-1)" "unprognostic (5.05e-2)" "unprognostic (1.44e-1)" "unprognostic (1.08e-2)" "unprognostic (1.05e-2)" "unprognostic (7.70e-2)" "unprognostic (9.03e-2)" "unprognostic (1.05e-1)" "unprognostic (6.82e-2)" "unprognostic (2.03e-1)" "unprognostic (6.35e-3)" C16orf46 FLJ32702 ENSG00000166455 "Chromosome 16 open reading frame 46" Q6P387 16 81053497-81077267 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 5.5" "Cell type enhanced" "Detected in some" "Early spermatids: 13.1;Epididymal efferent duct ciliated cells: 2.1;Fallopian tube ciliated cells: 3.3;Late primary spermatocytes: 4.0;Late spermatids: 14.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Pituitary gland - Somatotropes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA041136, HPA041379" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" Nucleoplasm Cytosol "HPA041136: , HPA041379: " "unprognostic (3.41e-1)" "unprognostic (2.98e-2)" "unprognostic (6.01e-2)" "unprognostic (1.05e-1)" "unprognostic (2.14e-1)" "potential prognostic unfavorable (5.86e-5)" "unprognostic (1.16e-1)" "unprognostic (1.14e-2)" "unprognostic (2.26e-1)" C16orf54 FLJ35681 ENSG00000185905 "Chromosome 16 open reading frame 54" Q6UWD8 16 29742463-29745990 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 38.9;lymphoid tissue: 19.7" "Cell type enhanced" "Detected in some" "B-cells: 29.3;Innate lymphoid cells: 59.3;Mast cells: 33.8;Megakaryocyte progenitors: 19.6;Megakaryocyte-Erythroid progenitors: 23.1;Megakaryocytes: 30.9;Monocyte progenitors: 19.3;Neutrophil progenitors: 43.2;Neutrophils: 137.7;NK-cells: 50.5;pDCs: 19.5;Plasma cells: 63.3;T-cells: 45.0" "Cell type enriched" "Detected in some" 5 "leukocyte: 34.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Leukemia: 15.6;Myeloma: 7.3" "Pituitary gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060546 Uncertain NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 6: Non-specific - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 8 "HPA060546: " "unprognostic (2.92e-1)" "unprognostic (1.06e-2)" "unprognostic (1.45e-3)" "unprognostic (5.69e-3)" "unprognostic (2.92e-2)" "unprognostic (1.06e-1)" "unprognostic (8.23e-2)" "unprognostic (9.38e-2)" "unprognostic (7.53e-3)" "unprognostic (5.19e-2)" "unprognostic (1.84e-2)" "unprognostic (3.04e-1)" "unprognostic (2.15e-2)" "unprognostic (6.86e-3)" "unprognostic (1.27e-3)" "unprognostic (4.07e-3)" "unprognostic (1.49e-1)" "unprognostic (2.10e-1)" "unprognostic (7.47e-2)" "unprognostic (3.72e-1)" "unprognostic (3.50e-1)" "unprognostic (1.39e-2)" "unprognostic (2.07e-1)" "potential prognostic favorable (6.63e-4)" "unprognostic (2.24e-1)" "unprognostic (6.66e-2)" "unprognostic (1.77e-1)" "unprognostic (5.42e-2)" C16orf74 MGC17624 ENSG00000154102 "Chromosome 16 open reading frame 74" Q96GX8 16 85690084-85751129 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 25.7" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 300.2;Cytotrophoblasts: 99.9;Epididymal basal cells: 81.7;Oocytes: 216.4;Plasma cells: 118.2;Prostatic hillock cells: 137.3;Retinal bipolar cells: 230.9;Rod photoreceptor cells: 285.7;Syncytiotrophoblasts: 145.9;Urothelial cells: 99.8" "Cell type enhanced" "Detected in many" "hippocampal CA1-3: 17.5;hippocampal CA4: 31.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049367 Uncertain Approved "Plasma membrane,Centrosome" NA NA "Cluster 18: Non-specific - Translation" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 29: Forebrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 2 "Plasma membrane" Centrosome "HPA049367: " "unprognostic (1.40e-1)" "unprognostic (9.46e-2)" "unprognostic (1.10e-1)" "unprognostic (6.49e-2)" "unprognostic (1.55e-3)" "unprognostic (5.67e-3)" "unprognostic (1.35e-3)" "unprognostic (1.55e-2)" "potential prognostic unfavorable (3.55e-4)" "unprognostic (8.64e-2)" "potential prognostic unfavorable (7.62e-4)" "unprognostic (1.66e-2)" "potential prognostic favorable (2.67e-4)" "unprognostic (1.50e-3)" "unprognostic (8.05e-2)" "potential prognostic unfavorable (5.83e-7)" "unprognostic (4.31e-2)" "unprognostic (2.26e-2)" "unprognostic (1.84e-1)" "unprognostic (3.13e-2)" "unprognostic (3.45e-2)" "validated prognostic unfavorable (2.30e-4)" "validated prognostic unfavorable (8.36e-8)" "unprognostic (1.64e-1)" "unprognostic (2.30e-1)" "unprognostic (1.93e-2)" "potential prognostic unfavorable (4.78e-6)" "unprognostic (1.32e-1)" "unprognostic (1.52e-1)" "unprognostic (2.00e-2)" "unprognostic (1.08e-3)" C16orf78 MGC33367 ENSG00000166152 "Chromosome 16 open reading frame 78" Q8WTQ4 16 49373804-49399431 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 458 "testis: 45.8" "Cell type enriched" "Detected in some" 6 "Late spermatids: 3113.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA042150 Approved "Connecting piece,Mid piece,Principal piece,End piece" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" "Connecting piece, Mid piece, Principal piece, End piece" "HPA042150: " C16orf82 TNT ENSG00000234186 "Chromosome 16 open reading frame 82" 16 27066927-27069166 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 693 "testis: 265.4" "Cell type enriched" "Detected in some" 8 "Late spermatids: 9208.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" C16orf86 FLJ41802 ENSG00000159761 "Chromosome 16 open reading frame 86" Q6ZW13 16 67666814-67668757 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 10.2;testis: 37.9" "Group enriched" "Detected in many" 5 "Early spermatids: 111.3;Late primary spermatocytes: 249.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "lymphoma: 1.6;Myeloma: 1.7" "Prostate - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA073475 Enhanced NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 67: Testis - Mixed function" "Cluster 22: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" "HPA073475: " "unprognostic (2.93e-1)" "unprognostic (1.73e-1)" "unprognostic (1.55e-1)" "unprognostic (3.18e-2)" "unprognostic (3.26e-3)" "unprognostic (9.63e-2)" "potential prognostic favorable (1.51e-11)" "unprognostic (4.02e-3)" "potential prognostic favorable (8.10e-5)" "unprognostic (5.21e-2)" "potential prognostic favorable (1.22e-4)" "unprognostic (8.67e-2)" "unprognostic (2.05e-1)" "unprognostic (1.03e-2)" "unprognostic (1.81e-1)" "unprognostic (3.07e-2)" "unprognostic (2.51e-1)" "unprognostic (4.67e-2)" "unprognostic (1.42e-1)" C16orf87 ENSG00000155330 "Chromosome 16 open reading frame 87" Q6PH81 16 46796603-46831180 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 17.2" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 164.7;Late primary spermatocytes: 194.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041179 Uncertain Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 11 Nucleoplasm "Nuclear bodies" "HPA041179: " "unprognostic (5.71e-2)" "unprognostic (9.40e-2)" "unprognostic (2.71e-1)" "unprognostic (1.92e-2)" "unprognostic (2.30e-1)" "unprognostic (2.20e-1)" "unprognostic (2.56e-2)" "potential prognostic favorable (2.23e-5)" "potential prognostic unfavorable (9.44e-4)" "unprognostic (1.20e-1)" "potential prognostic favorable (6.18e-4)" "unprognostic (2.63e-1)" "unprognostic (2.30e-3)" "unprognostic (1.22e-1)" "unprognostic (1.26e-2)" "unprognostic (2.11e-2)" "unprognostic (1.89e-2)" "unprognostic (7.65e-2)" "unprognostic (2.16e-1)" "unprognostic (1.43e-1)" "unprognostic (2.36e-3)" "potential prognostic unfavorable (4.20e-5)" "unprognostic (2.96e-3)" "unprognostic (1.60e-1)" "unprognostic (1.37e-2)" "unprognostic (2.25e-1)" "unprognostic (8.26e-2)" "potential prognostic unfavorable (2.05e-4)" "unprognostic (2.72e-1)" "unprognostic (8.58e-2)" "unprognostic (7.87e-2)" C16orf89 MGC45438 ENSG00000153446 "Chromosome 16 open reading frame 89" Q6UX73 16 5044122-5066110 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 102.1;thyroid gland: 214.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 262.6;Conjunctival goblet cells: 59.2;Epididymal principal cells: 203.2;Gastric chief cells: 140.9;Mucous neck cells: 82.3;Parietal cells: 81.3;Respiratory deuterosomal cells: 49.8;Respiratory secretory cells: 98.8;Transitional alveolar cells: 239.7" "Group enriched" "Detected in many" 4 "astrocyte: 31.8;Bergmann glia: 24.1;fibroblast: 69.4;pericyte: 31.2" "Group enriched" "Detected in many" 13 "Kidney Chromophobe (TCGA): 85.4;Lung Adenocarcinoma (TCGA): 252.0;Thyroid Carcinoma (TCGA): 305.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 10 "thyroid cancer: 14.2" "Colon - Fibroblasts, Lung - Alveolar cells type 2, Prostate - Fibroblasts, Stomach - Chief cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA013613, HPA016934" Enhanced "Secreted to blood" "No annotated function" NA NA 3800000 "Cluster 33: Thyroid gland - Tissue development" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 81: Alveolar cells - Lung function" "HPA013613: , HPA016934: " "unprognostic (8.05e-2)" "unprognostic (3.28e-2)" "unprognostic (6.05e-2)" "unprognostic (2.31e-2)" "unprognostic (2.03e-1)" "unprognostic (2.93e-1)" "unprognostic (1.47e-3)" "unprognostic (4.37e-3)" "unprognostic (1.34e-1)" "unprognostic (1.61e-2)" "unprognostic (3.44e-1)" "potential prognostic unfavorable (5.99e-6)" "potential prognostic favorable (7.35e-4)" "unprognostic (5.43e-2)" "unprognostic (2.16e-2)" "unprognostic (3.50e-1)" "unprognostic (2.10e-1)" "unprognostic (3.72e-3)" "unprognostic (5.68e-2)" "unprognostic (1.70e-2)" "unprognostic (4.26e-2)" "unprognostic (7.13e-2)" "unprognostic (3.15e-2)" "unprognostic (8.39e-3)" "unprognostic (1.86e-1)" "unprognostic (4.20e-2)" "unprognostic (5.13e-2)" C16orf90 LOC646174 ENSG00000215131 "Chromosome 16 open reading frame 90" A8MZG2 16 3493484-3495489 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 419 "testis: 46.7" "Group enriched" "Detected in some" 34 "Early spermatids: 260.4;Late primary spermatocytes: 195.0;Late spermatids: 779.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 15: Non-specific - Transcription" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" C16orf91 "CCSMST1, gs103, URLC5" ENSG00000174109 "Chromosome 16 open reading frame 91" Q4G0I0 16 1419752-1420756 "Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 62.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 54: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" "unprognostic (1.82e-1)" "potential prognostic unfavorable (9.58e-4)" "unprognostic (2.19e-1)" "unprognostic (8.83e-2)" "unprognostic (1.15e-1)" "unprognostic (2.61e-1)" "unprognostic (7.47e-2)" "unprognostic (1.40e-1)" "unprognostic (4.18e-2)" "unprognostic (3.35e-2)" "unprognostic (7.21e-3)" "unprognostic (1.69e-1)" "unprognostic (4.35e-2)" "unprognostic (2.04e-3)" "unprognostic (5.85e-2)" "potential prognostic unfavorable (6.83e-4)" "unprognostic (9.03e-2)" "unprognostic (2.11e-1)" "unprognostic (1.62e-2)" "unprognostic (1.63e-1)" "unprognostic (2.27e-1)" "unprognostic (1.42e-3)" "unprognostic (2.12e-1)" "unprognostic (2.50e-2)" "unprognostic (7.77e-3)" "unprognostic (1.28e-1)" "unprognostic (6.97e-3)" "unprognostic (3.81e-2)" "unprognostic (3.43e-1)" "unprognostic (2.45e-1)" "unprognostic (2.89e-2)" C16orf92 "FIMP, FLJ25404" ENSG00000167194 "Chromosome 16 open reading frame 92" Q96LL3 16 30023198-30027736 "Predicted intracellular proteins, Predicted membrane proteins" Fertilization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "retina: 33.2;testis: 15.1" "Group enriched" "Detected in some" 5 "Early spermatids: 132.1;Late primary spermatocytes: 59.0;Late spermatids: 50.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Glioblastoma Multiforme (TCGA): 1.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Neuroblastoma: 8.3" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 42: Retina - Visual perception" "Cluster 35: Non-specific - DNA binding" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 10 "unprognostic (1.87e-1)" C16orf95 ENSG00000260456 "Chromosome 16 open reading frame 95" Q9H693 16 87083562-87317420 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 15 "testis: 98.4" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 42.7;Early primary spermatocytes: 83.2;Early spermatids: 112.2;Erythrocyte progenitors: 66.3;Late primary spermatocytes: 235.4;Late spermatids: 284.9;Megakaryocytes: 43.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA040850, HPA067924" Supported Approved "Endoplasmic reticulum" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 23: Testis - Spermatogenesis" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" "Endoplasmic reticulum" "HPA040850: , HPA067924: " "unprognostic (2.64e-2)" "unprognostic (3.41e-1)" "unprognostic (1.05e-2)" "unprognostic (1.70e-1)" "unprognostic (1.27e-1)" "unprognostic (4.40e-2)" "unprognostic (3.10e-3)" "unprognostic (6.88e-2)" "unprognostic (1.90e-1)" "unprognostic (4.30e-2)" "unprognostic (1.29e-2)" "unprognostic (1.46e-2)" "unprognostic (1.67e-1)" "unprognostic (2.43e-1)" "unprognostic (1.38e-2)" "unprognostic (6.50e-2)" "unprognostic (6.88e-2)" "unprognostic (2.29e-1)" "unprognostic (2.39e-2)" "unprognostic (3.77e-2)" "unprognostic (1.70e-1)" "unprognostic (6.42e-3)" "unprognostic (3.20e-1)" "unprognostic (9.73e-2)" "unprognostic (3.81e-2)" "unprognostic (1.58e-1)" "unprognostic (3.70e-3)" "unprognostic (1.88e-1)" C16orf96 ENSG00000205832 "Chromosome 16 open reading frame 96" A6NNT2 16 4556340-4600758 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 17 "testis: 9.7" "Cell type enhanced" "Detected in many" "Early spermatids: 17.2;Endometrial luminal cells: 17.6;Late primary spermatocytes: 29.5;Müller glia: 14.2;Retinal bipolar cells: 12.5;Retinal ganglion cells: 15.5" "Cell type enhanced" "Detected in many" "astrocyte: 8.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" HPA042009 Approved "Centriolar satellite" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 6: Non-specific - Immune response" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" "Centriolar satellite" "HPA042009: " "unprognostic (2.32e-1)" C17orf100 LOC388327 ENSG00000256806 "Chromosome 17 open reading frame 100" A8MU93 17 6651762-6693202 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 16.5;Epididymal principal cells: 22.5;Late primary spermatocytes: 13.7;Late spermatids: 23.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA046824 Approved "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes No "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 22: Epididymis - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" Nucleoplasm "Cytokinetic bridge, Cytosol" "HPA046824: " "unprognostic (1.45e-2)" "unprognostic (6.39e-2)" "unprognostic (7.90e-2)" "unprognostic (3.23e-1)" "unprognostic (8.29e-2)" "unprognostic (3.15e-2)" "unprognostic (1.59e-1)" "unprognostic (3.04e-2)" "unprognostic (3.93e-1)" "potential prognostic favorable (3.04e-5)" "unprognostic (2.20e-2)" "unprognostic (1.50e-2)" "unprognostic (4.71e-2)" "unprognostic (5.19e-2)" "unprognostic (2.62e-1)" "unprognostic (1.94e-1)" "unprognostic (2.35e-1)" "unprognostic (2.86e-3)" "unprognostic (5.25e-3)" "unprognostic (6.54e-2)" "unprognostic (2.44e-2)" "unprognostic (1.47e-1)" "unprognostic (4.82e-2)" "unprognostic (6.63e-2)" "unprognostic (9.83e-2)" "unprognostic (3.67e-1)" "unprognostic (2.37e-1)" "unprognostic (2.57e-1)" "unprognostic (2.60e-1)" "unprognostic (2.22e-1)" C17orf107 ENSG00000205710 "Chromosome 17 open reading frame 107" Q6ZR85 17 4899418-4902934 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 14.3;pituitary gland: 24.2" "Cell type enriched" "Detected in many" 6 "Late spermatids: 447.6" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "neutrophil: 2.9" "Lineage enriched" "Detected in single" 7 "granulocytes: 2.9" "Low cancer specificity" "Detected in some" "Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Corticotropes, Prostate - Prostate glandular cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA069713 Uncertain Approved Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 20: Pituitary gland - Hormone signaling" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 7: Liver cancer - Metabolism" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" Nucleoplasm "HPA069713: " "unprognostic (3.58e-1)" "unprognostic (1.50e-3)" "unprognostic (1.96e-1)" "unprognostic (1.26e-2)" "unprognostic (5.04e-2)" "unprognostic (1.79e-3)" "unprognostic (1.24e-1)" "potential prognostic favorable (2.06e-6)" "unprognostic (7.74e-2)" "potential prognostic favorable (7.64e-5)" "unprognostic (7.48e-2)" "unprognostic (4.59e-2)" "unprognostic (1.92e-2)" "unprognostic (1.32e-1)" "unprognostic (2.26e-1)" "unprognostic (3.48e-2)" "unprognostic (2.77e-1)" "unprognostic (1.19e-2)" "unprognostic (2.74e-3)" "unprognostic (4.00e-2)" "unprognostic (9.56e-2)" "unprognostic (1.67e-1)" "unprognostic (5.56e-2)" "unprognostic (1.04e-1)" "unprognostic (3.53e-1)" "unprognostic (4.57e-2)" "unprognostic (2.58e-1)" C17orf113 ENSG00000267221 "Chromosome 17 open reading frame 113" A0A1B0GUU1 17 42038232-42050601 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 21: Testis - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 55: Lymphoma - Immune response" "unprognostic (1.24e-1)" "unprognostic (2.85e-2)" "unprognostic (3.83e-1)" "unprognostic (9.35e-2)" "unprognostic (1.03e-1)" "unprognostic (3.16e-1)" "unprognostic (1.01e-2)" "unprognostic (9.36e-2)" "potential prognostic favorable (2.49e-4)" "unprognostic (2.36e-3)" "unprognostic (1.38e-2)" "unprognostic (1.96e-2)" "unprognostic (2.83e-1)" "unprognostic (4.40e-3)" "unprognostic (5.45e-2)" "unprognostic (8.57e-2)" "unprognostic (2.29e-1)" "unprognostic (4.48e-2)" "unprognostic (4.21e-2)" "unprognostic (2.84e-1)" "potential prognostic unfavorable (8.40e-4)" "unprognostic (6.34e-2)" C17orf114 ENSG00000262165 "Chromosome 17 open reading frame 114" A0A1B0GUV1 17 4801159-4807013 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 6.3" "Cell type enhanced" "Detected in many" "Cholangiocytes: 10.0;Esophageal apical cells: 24.4;Undifferentiated spermatogonia: 10.6" "Cell type enhanced" "Detected in many" "Bergmann glia: 11.9;ependymal cell: 13.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "basal ganglia: 2.9" "Not detected" "Not detected" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 39: Astrocytes - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" "unprognostic (1.15e-1)" "unprognostic (1.87e-1)" "potential prognostic favorable (3.45e-6)" "unprognostic (6.37e-2)" "unprognostic (1.58e-2)" "unprognostic (5.07e-2)" "unprognostic (5.70e-2)" "unprognostic (2.52e-1)" "unprognostic (2.56e-2)" "unprognostic (1.34e-1)" "unprognostic (5.56e-2)" "unprognostic (2.64e-2)" "unprognostic (5.32e-1)" C17orf49 "BAP18, HEPIS, MGC49942" ENSG00000258315 "Chromosome 17 open reading frame 49" Q8IXM2 17 7014495-7017525 "Essential proteins, Predicted intracellular proteins" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 10.4;Brain inhibitory neurons: 7.7;Enteric transient amplifying cells: 6.8;Ependymal cells: 9.2;Epididymal efferent duct absorptive cells: 6.5;Megakaryocytes: 6.2;Microglia: 6.9;Oligodendrocyte progenitor cells: 9.0;Oligodendrocytes: 13.0;Other brain neurons: 11.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022961, HPA024457" Supported Uncertain Nucleoplasm,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 27: Non-specific - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" 28 Nucleoplasm Cytosol "HPA022961: , HPA024457: " "unprognostic (1.44e-1)" "unprognostic (5.93e-3)" "unprognostic (1.50e-1)" "unprognostic (1.34e-3)" "unprognostic (8.83e-2)" "unprognostic (3.56e-2)" "unprognostic (3.56e-1)" "potential prognostic favorable (7.83e-5)" "unprognostic (6.35e-2)" "unprognostic (1.14e-1)" "unprognostic (1.35e-1)" "unprognostic (2.22e-1)" "unprognostic (9.34e-3)" "unprognostic (1.05e-2)" "unprognostic (2.32e-2)" "unprognostic (7.25e-2)" "unprognostic (5.51e-2)" "unprognostic (2.33e-1)" "unprognostic (3.02e-1)" "unprognostic (3.45e-2)" "unprognostic (2.38e-1)" "unprognostic (4.42e-2)" "unprognostic (3.90e-2)" "unprognostic (1.22e-1)" "unprognostic (1.21e-1)" "unprognostic (4.42e-2)" "unprognostic (1.42e-1)" "unprognostic (9.95e-2)" "unprognostic (2.38e-1)" "unprognostic (9.81e-3)" "unprognostic (4.27e-3)" C17orf50 ENSG00000270806 "Chromosome 17 open reading frame 50" Q8WW18 17 35760887-35765079 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 84 "testis: 94.2" "Group enriched" "Detected in some" 80 "Early spermatids: 695.3;Late primary spermatocytes: 596.1;Late spermatids: 2113.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in single" "Gallbladder cancer: 2.1" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "HPA043184, HPA063464" Supported Nucleoplasm Yes NA "Cluster 30: Non-specific - DNA binding" "Cluster 79: Testis - Spermatogenesis" "Cluster 33: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 6 Nucleoplasm "HPA043184: , HPA063464: " C17orf58 ENSG00000186665 "Chromosome 17 open reading frame 58" Q2M2W7 17 67991099-67996469 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 33.5" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 53.9;Decidual stromal cells: 68.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "cerebellum: 53.9" HPA023036 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 31: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 108: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "HPA023036: " "unprognostic (2.87e-1)" "unprognostic (8.56e-2)" "unprognostic (7.48e-2)" "unprognostic (4.36e-2)" "unprognostic (4.53e-2)" "unprognostic (9.63e-2)" "unprognostic (2.55e-1)" "unprognostic (1.22e-1)" "unprognostic (2.51e-3)" "unprognostic (2.14e-3)" "unprognostic (5.11e-3)" "unprognostic (6.39e-2)" "potential prognostic unfavorable (1.36e-4)" "unprognostic (3.25e-2)" "unprognostic (3.97e-2)" "unprognostic (1.00e-3)" "unprognostic (2.72e-2)" "unprognostic (7.06e-3)" "unprognostic (1.35e-1)" "unprognostic (4.84e-2)" "unprognostic (8.63e-2)" "unprognostic (8.10e-2)" "unprognostic (1.68e-1)" "unprognostic (1.08e-1)" "unprognostic (3.52e-1)" "unprognostic (2.84e-1)" "unprognostic (3.88e-1)" "unprognostic (5.37e-3)" "unprognostic (2.77e-1)" "unprognostic (2.70e-1)" "unprognostic (1.31e-1)" C17orf67 ENSG00000214226 "Chromosome 17 open reading frame 67" Q0P5P2 17 56791913-56838773 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Lymphatic endothelial cells: 47.5;Pancreatic duct cells: 64.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 5 "olfactory bulb: 3.1" "Region enhanced" "Detected in many" "spinal cord: 29.1" HPA043479 Approved "Secreted to blood" "No annotated function" NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 25: Non-specific - Transcription" "Cluster 6: Leukemia - Signal transduction" "Cluster 75: Non-specific - Chaperones and protein folding" 2 "HPA043479: " "unprognostic (2.27e-1)" "potential prognostic unfavorable (7.69e-4)" "unprognostic (4.71e-2)" "unprognostic (6.34e-2)" "unprognostic (2.07e-2)" "potential prognostic unfavorable (8.01e-4)" "unprognostic (8.01e-3)" "unprognostic (1.99e-1)" "unprognostic (4.66e-3)" "unprognostic (1.36e-2)" "unprognostic (1.49e-1)" "unprognostic (1.74e-1)" "unprognostic (2.93e-1)" "unprognostic (1.38e-1)" "unprognostic (3.94e-2)" "unprognostic (1.21e-1)" "unprognostic (1.57e-1)" "unprognostic (1.07e-3)" "unprognostic (2.11e-2)" "unprognostic (1.21e-2)" "unprognostic (5.60e-3)" "unprognostic (1.87e-1)" "unprognostic (1.77e-1)" "unprognostic (1.08e-1)" C17orf75 "NJMU-R1, SRI2" ENSG00000108666 "Chromosome 17 open reading frame 75" Q9HAS0 17 32324565-32350023 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 84.9;Late primary spermatocytes: 63.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004061, HPA075333" Approved Approved Approved "Golgi apparatus,Cytosol" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 3: Early primary spermatocytes - Early meiosis" 13 "Golgi apparatus, Cytosol" "HPA004061: , HPA075333: " "unprognostic (1.28e-1)" "unprognostic (1.45e-2)" "unprognostic (3.23e-1)" "unprognostic (1.64e-1)" "unprognostic (1.43e-1)" "unprognostic (1.58e-1)" "unprognostic (3.77e-1)" "unprognostic (6.50e-3)" "unprognostic (5.81e-2)" "potential prognostic unfavorable (4.38e-5)" "unprognostic (4.25e-3)" "unprognostic (2.73e-1)" "unprognostic (1.80e-1)" "potential prognostic unfavorable (1.70e-5)" "unprognostic (5.53e-3)" "unprognostic (3.34e-1)" "unprognostic (2.09e-2)" "unprognostic (9.94e-2)" "unprognostic (4.57e-2)" "unprognostic (1.87e-2)" "unprognostic (6.16e-3)" "unprognostic (3.72e-1)" "potential prognostic unfavorable (2.25e-4)" "unprognostic (2.31e-1)" "unprognostic (8.57e-3)" "unprognostic (2.31e-2)" "unprognostic (1.21e-2)" "unprognostic (1.48e-1)" "unprognostic (1.10e-1)" "unprognostic (1.30e-1)" "unprognostic (1.28e-1)" C17orf78 FLJ39647 ENSG00000278505 "Chromosome 17 open reading frame 78" Q8N4C9 17 37375985-37392708 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 95 "intestine: 120.0" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 3.3;Brain inhibitory neurons: 3.3;Cardiomyocytes: 1.9;Enterocytes: 16.3;Epicardial cells: 6.8;Loop of henle epithelial cells: 1.8;Medullary thymic epithelial cells: 2.4;Oligodendrocyte progenitor cells: 1.9;Other brain neurons: 4.4;Papillary tip epithelial cells: 1.6" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in single" "Stomach Adenocarcinoma (TCGA): 1.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 1: Enterocytes - Absorption and Digestion" 2 "unprognostic (2.59e-2)" C17orf80 "FLJ20721, HLC-8, MIG3, SPEP1" ENSG00000141219 "Chromosome 17 open reading frame 80" Q9BSJ5 17 73232233-73248959 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 159.5;Late primary spermatocytes: 191.9;Late spermatids: 149.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010974, HPA012896, HPA073479" Uncertain Approved Mitochondria,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 16 Mitochondria Cytosol "HPA010974: , HPA012896: , HPA073479: " "unprognostic (1.51e-1)" "unprognostic (3.29e-2)" "unprognostic (2.94e-1)" "unprognostic (2.81e-2)" "unprognostic (2.49e-2)" "unprognostic (2.69e-1)" "unprognostic (1.66e-2)" "unprognostic (1.09e-2)" "unprognostic (2.71e-1)" "potential prognostic unfavorable (1.33e-4)" "potential prognostic favorable (2.24e-5)" "unprognostic (3.93e-3)" "unprognostic (5.64e-2)" "potential prognostic unfavorable (3.27e-5)" "unprognostic (3.88e-2)" "unprognostic (3.74e-1)" "unprognostic (4.36e-2)" "unprognostic (1.97e-1)" "unprognostic (2.45e-3)" "unprognostic (1.30e-1)" "unprognostic (1.69e-1)" "unprognostic (3.14e-3)" "unprognostic (6.26e-3)" "unprognostic (8.25e-2)" "unprognostic (2.10e-3)" "unprognostic (2.28e-1)" "unprognostic (7.53e-3)" "unprognostic (1.97e-1)" "unprognostic (4.38e-1)" "unprognostic (3.12e-2)" "unprognostic (2.19e-1)" C17orf97 "LIAT1, LOC400566" ENSG00000187624 "Chromosome 17 open reading frame 97" Q6ZQX7 17 410325-431062 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "testis: 55.1" "Cell type enriched" "Detected in some" 8 "Late spermatids: 310.8" "Cell type enhanced" "Detected in many" "ependymal cell: 43.9" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 16.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA023583 Approved Approved Nucleoli,Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 67: Testis - Mixed function" "Cluster 17: Choroid plexus - Cilium" "Cluster 42: Non-specific - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" Nucleoli Cytosol "HPA023583: " "unprognostic (4.27e-2)" "unprognostic (3.06e-1)" "unprognostic (2.50e-1)" "unprognostic (1.24e-1)" "unprognostic (1.00e-1)" "unprognostic (1.01e-3)" "unprognostic (1.39e-2)" "potential prognostic unfavorable (4.54e-4)" "unprognostic (1.65e-1)" "unprognostic (3.10e-1)" "unprognostic (5.76e-3)" "unprognostic (9.38e-2)" "unprognostic (1.28e-2)" "unprognostic (6.00e-3)" "unprognostic (9.16e-3)" "unprognostic (7.05e-3)" "unprognostic (3.93e-1)" "unprognostic (9.85e-2)" "unprognostic (1.97e-1)" "unprognostic (1.06e-1)" "unprognostic (9.78e-2)" "unprognostic (1.07e-1)" "unprognostic (3.85e-2)" "unprognostic (1.02e-1)" "unprognostic (2.63e-1)" "unprognostic (9.11e-3)" "unprognostic (2.54e-1)" "unprognostic (7.45e-2)" "unprognostic (3.18e-2)" C17orf98 LOC388381 ENSG00000275489 "Chromosome 17 open reading frame 98" A8MV24 17 38835086-38841438 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 68 "testis: 18.8" "Group enriched" "Detected in some" 12 "Early spermatids: 228.2;Late primary spermatocytes: 168.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051696 Uncertain NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 35: RS4;11 - Unknown function" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" "HPA051696: " C17orf99 "GLPG464, UNQ464" ENSG00000187997 "Chromosome 17 open reading frame 99" Q6UX52 17 78146385-78166297 "Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "bone marrow: 8.2" "Cell type enriched" "Detected in some" 6 "Erythrocyte progenitors: 40.8" "Cell type enhanced" "Detected in some" "fibroblast: 2.9;pericyte: 1.7" "Cancer enhanced" "Detected in single" "Lung Squamous Cell Carcinoma (TCGA): 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Leukemia: 1.1;lymphoma: 2.6" "Not detected" "Not detected" HPA029655 Uncertain "Secreted to blood" Cytokine NA NA 2190000 "Cluster 15: Bone marrow - Innate immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" "HPA029655: " "unprognostic (1.45e-1)" "unprognostic (3.07e-2)" C18orf21 "HsT3108, PNAS-124, PNAS-131" ENSG00000141428 "Chromosome 18 open reading frame 21" Q32NC0 18 35972625-35979286 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 116.2;Late primary spermatocytes: 270.7;Late spermatids: 84.9;Oocytes: 59.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065505, HPA067322" Uncertain Approved "Nucleoli,Plasma membrane" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 2: Neurons - Nucleosome" "Cluster 13: Non-specific - Mixed function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 90 "Nucleoli, Plasma membrane" "HPA065505: , HPA067322: " "unprognostic (6.86e-2)" "unprognostic (4.90e-2)" "unprognostic (1.62e-1)" "unprognostic (2.71e-2)" "unprognostic (3.49e-2)" "unprognostic (3.25e-2)" "unprognostic (1.39e-1)" "unprognostic (3.11e-2)" "unprognostic (2.58e-2)" "unprognostic (1.72e-2)" "unprognostic (3.49e-2)" "unprognostic (1.87e-3)" "unprognostic (8.12e-2)" "validated prognostic unfavorable (2.49e-7)" "validated prognostic unfavorable (2.81e-4)" "unprognostic (2.09e-1)" "unprognostic (8.36e-2)" "unprognostic (4.01e-3)" "unprognostic (4.95e-3)" "unprognostic (4.58e-3)" "unprognostic (9.99e-2)" "unprognostic (3.54e-2)" "unprognostic (1.18e-2)" "unprognostic (1.72e-2)" "unprognostic (2.04e-1)" "unprognostic (4.66e-3)" "unprognostic (9.34e-3)" "unprognostic (1.58e-2)" "unprognostic (3.48e-2)" "unprognostic (4.12e-1)" "unprognostic (2.97e-1)" C18orf25 "Ark2N, ARKL1, MGC12909, RNF111L1" ENSG00000152242 "Chromosome 18 open reading frame 25" Q96B23 18 46173553-46266992 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial glandular cells: 250.0;Esophageal apical cells: 777.4;Neutrophil progenitors: 295.7;Neutrophils: 234.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051314, HPA051899" Approved Approved Nucleoplasm,Cytosol No No "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 84: Apical squamous epithelium - Cornification" 22 Nucleoplasm Cytosol "HPA051314: , HPA051899: " "unprognostic (1.55e-3)" "unprognostic (4.66e-2)" "unprognostic (3.51e-1)" "unprognostic (5.41e-3)" "unprognostic (4.45e-2)" "unprognostic (1.42e-1)" "unprognostic (3.05e-1)" "unprognostic (8.87e-2)" "unprognostic (6.83e-2)" "unprognostic (3.57e-2)" "unprognostic (1.18e-3)" "unprognostic (1.35e-3)" "unprognostic (1.34e-1)" "potential prognostic unfavorable (9.48e-4)" "unprognostic (1.55e-2)" "unprognostic (1.92e-1)" "unprognostic (9.69e-2)" "unprognostic (8.83e-2)" "unprognostic (1.70e-3)" "unprognostic (2.52e-1)" "unprognostic (3.45e-1)" "unprognostic (3.54e-2)" "unprognostic (2.98e-3)" "unprognostic (2.69e-2)" "unprognostic (1.01e-2)" "unprognostic (6.16e-2)" "unprognostic (9.02e-2)" "unprognostic (2.56e-2)" "unprognostic (1.35e-1)" "unprognostic (1.28e-1)" "unprognostic (1.80e-1)" C18orf32 FLJ23458 ENSG00000177576 "Chromosome 18 open reading frame 32" Q8TCD1 18 49477243-49487252 "Disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 258.2;Gastric chief cells: 139.8;Late spermatids: 250.6;Parietal cells: 312.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040921 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 15: Non-specific - Protein processing" 1 Vesicles Nucleoplasm "HPA040921: " "unprognostic (9.79e-2)" "unprognostic (2.02e-2)" "unprognostic (1.48e-1)" "unprognostic (1.34e-3)" "unprognostic (1.56e-2)" "unprognostic (1.55e-2)" "unprognostic (6.41e-2)" "unprognostic (2.04e-2)" "unprognostic (1.56e-1)" "unprognostic (1.09e-1)" "potential prognostic favorable (2.16e-4)" "unprognostic (6.29e-3)" "unprognostic (2.20e-1)" "unprognostic (1.42e-1)" "unprognostic (1.51e-1)" "unprognostic (7.90e-2)" "unprognostic (1.09e-2)" "unprognostic (1.11e-1)" "unprognostic (8.44e-2)" "unprognostic (1.05e-1)" "unprognostic (8.18e-3)" "unprognostic (1.86e-1)" "unprognostic (1.76e-1)" "unprognostic (1.66e-1)" "unprognostic (1.67e-1)" "potential prognostic unfavorable (3.38e-4)" "unprognostic (1.00e-2)" "unprognostic (1.78e-1)" "unprognostic (6.72e-2)" "unprognostic (2.08e-1)" "unprognostic (2.56e-1)" C18orf54 "LAS2, MGC33382" ENSG00000166845 "Chromosome 18 open reading frame 54" Q8IYD9 18 54357906-54385218 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 16.2" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 47.7;Early spermatids: 111.9;Extravillous trophoblasts: 35.6;Late primary spermatocytes: 92.0;Late spermatids: 39.2;Megakaryocyte progenitors: 22.8;Megakaryocytes: 24.7;Oligodendrocytes: 18.3" "Cell type enhanced" "Detected in many" "oligodendrocyte: 26.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.9" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077475 Approved Nucleoplasm,Vesicles,Cytosol "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 39: Testis - Nuclear processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 8 Cytosol "Nucleoplasm, Vesicles" "HPA077475: " "unprognostic (1.14e-1)" "unprognostic (2.53e-1)" "unprognostic (8.47e-2)" "unprognostic (3.06e-1)" "unprognostic (2.15e-1)" "unprognostic (1.04e-1)" "unprognostic (3.22e-1)" "unprognostic (6.08e-2)" "unprognostic (5.93e-2)" "unprognostic (9.08e-2)" "unprognostic (2.15e-1)" "unprognostic (2.80e-1)" "validated prognostic unfavorable (1.52e-5)" "validated prognostic unfavorable (2.69e-5)" "unprognostic (4.61e-2)" "unprognostic (2.49e-1)" "unprognostic (9.43e-2)" "unprognostic (7.40e-2)" "potential prognostic unfavorable (1.12e-4)" "unprognostic (2.69e-2)" "unprognostic (2.34e-1)" "unprognostic (7.94e-3)" "unprognostic (3.89e-1)" "unprognostic (2.30e-1)" "unprognostic (6.99e-3)" C18orf63 DKFZP781G0119 ENSG00000206043 "Chromosome 18 open reading frame 63" Q68DL7 18 74315839-74359189 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 43 "testis: 9.2" "Cell type enriched" "Detected in some" 5 "Early primary spermatocytes: 239.6" "Cell type enhanced" "Detected in some" "Bergmann glia: 2.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Spermatocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA042233 Approved Mitochondria NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 3: Early primary spermatocytes - Early meiosis" Mitochondria "HPA042233: " C19orf12 "DKFZP762D096, MGC10922, MPAN, NBIA4, SPG43" ENSG00000131943 "Chromosome 19 open reading frame 12" Q9NSK7 19 29698937-29715789 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 110.6;tongue: 98.1" "Cell type enhanced" "Detected in many" "Adipocytes: 133.0;Enterocytes: 160.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046930 Approved Supported Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 76: Non-specific - Metabolism" "Cluster 1: Neurons - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 89: Adipocytes - Lipid metabolism" Cytosol "HPA046930: " "unprognostic (7.11e-2)" "unprognostic (1.47e-1)" "unprognostic (5.13e-2)" "unprognostic (2.87e-3)" "unprognostic (1.80e-1)" "unprognostic (1.20e-1)" "unprognostic (1.90e-1)" "unprognostic (1.41e-1)" "unprognostic (6.08e-2)" "unprognostic (7.50e-3)" "unprognostic (1.87e-3)" "unprognostic (9.14e-2)" "unprognostic (3.39e-1)" "unprognostic (2.91e-2)" "potential prognostic favorable (3.34e-5)" "unprognostic (1.36e-1)" "unprognostic (3.00e-1)" "unprognostic (3.86e-2)" "unprognostic (3.23e-1)" "unprognostic (4.33e-3)" "unprognostic (2.30e-2)" "unprognostic (1.17e-1)" "unprognostic (1.40e-2)" "unprognostic (1.03e-1)" "unprognostic (4.88e-2)" "unprognostic (4.06e-2)" "unprognostic (2.81e-1)" "unprognostic (9.03e-2)" "unprognostic (6.21e-2)" "unprognostic (1.70e-2)" "unprognostic (5.57e-2)" C19orf18 MGC41906 ENSG00000177025 "Chromosome 19 open reading frame 18" Q8NEA5 19 57958437-57974534 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 15.2;testis: 11.9" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 65.6;Early spermatids: 134.9;Ependymal cells: 49.0;Late primary spermatocytes: 122.3;Myonuclei: 47.1;Sertoli cells: 41.9" "Cell type enhanced" "Detected in all" "astrocyte: 41.2;choroid plexus epithelial cell: 46.5;ependymal cell: 49.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "HPA014527, HPA079195" Approved Approved "Golgi apparatus" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 4: Non-specific - Transcription" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 3 "Golgi apparatus" "HPA014527: , HPA079195: " "unprognostic (9.53e-2)" "unprognostic (3.29e-1)" "unprognostic (4.60e-2)" "potential prognostic favorable (4.65e-4)" "unprognostic (1.72e-1)" "unprognostic (2.41e-1)" "unprognostic (1.74e-3)" "unprognostic (1.29e-1)" "unprognostic (1.76e-1)" "unprognostic (3.22e-2)" "unprognostic (1.31e-1)" "potential prognostic favorable (6.98e-5)" "unprognostic (3.38e-2)" "unprognostic (6.62e-3)" "unprognostic (9.75e-2)" "unprognostic (3.71e-2)" "unprognostic (1.76e-2)" C19orf25 FLJ36666 ENSG00000119559 "Chromosome 19 open reading frame 25" Q9UFG5 19 1461143-1479219 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050270, HPA067491" Approved Approved "Intermediate filaments" No No "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 65: Non-specific - Cell growth & division" 45 "Intermediate filaments" "HPA050270: , HPA067491: " "unprognostic (2.16e-2)" "unprognostic (1.04e-1)" "unprognostic (7.13e-2)" "unprognostic (1.74e-1)" "unprognostic (1.03e-1)" "unprognostic (3.82e-2)" "unprognostic (1.90e-1)" "unprognostic (6.94e-2)" "unprognostic (3.77e-3)" "unprognostic (1.54e-3)" "potential prognostic favorable (2.47e-6)" "unprognostic (2.15e-3)" "potential prognostic favorable (2.88e-4)" "unprognostic (1.60e-3)" "unprognostic (2.05e-1)" "unprognostic (3.45e-1)" "unprognostic (3.42e-2)" "unprognostic (1.52e-2)" "unprognostic (2.79e-1)" "unprognostic (4.61e-3)" "unprognostic (2.56e-1)" "unprognostic (2.47e-3)" "unprognostic (5.05e-2)" "unprognostic (2.85e-1)" "unprognostic (8.38e-2)" "unprognostic (7.36e-2)" "unprognostic (6.35e-2)" "unprognostic (1.02e-2)" "unprognostic (1.29e-1)" "unprognostic (4.39e-1)" "unprognostic (1.49e-2)" C19orf33 "H2RSP, IMUP, IMUP-1, IMUP-2" ENSG00000167644 "Chromosome 19 open reading frame 33" Q9GZP8 19 38304164-38305006 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 689.2;skin 1: 440.6" "Cell type enhanced" "Detected in many" "Colonocytes: 2467.9;Enteric transient amplifying cells: 531.9;Enterocytes: 1591.9;Esophageal apical cells: 2363.4;Esophageal suprabasal cells: 878.3;Fallopian secretory cells: 537.1;Foveolar cells: 752.4;Goblet cells: 851.2" "Group enriched" "Detected in some" 15 "endothelial cell: 5.5;fibroblast: 5.1;vascular associated smooth muscle cell: 2.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 10 "myeloid DC: 22.3" "Lineage enriched" "Detected in many" 10 "dendritic cells: 22.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "HPA054406, HPA059696" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" No No 170000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 47: Endothelial cells - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 1 Nucleoplasm "Plasma membrane, Cytosol" "HPA054406: , HPA059696: " "unprognostic (1.15e-1)" "unprognostic (1.85e-1)" "unprognostic (3.76e-3)" "unprognostic (9.97e-2)" "unprognostic (6.00e-2)" "unprognostic (5.79e-3)" "unprognostic (5.84e-3)" "unprognostic (1.58e-2)" "unprognostic (1.13e-2)" "unprognostic (2.60e-1)" "potential prognostic favorable (2.22e-5)" "unprognostic (1.84e-1)" "unprognostic (2.06e-2)" "potential prognostic unfavorable (1.19e-6)" "unprognostic (1.21e-1)" "unprognostic (2.69e-2)" "unprognostic (1.26e-3)" "unprognostic (9.77e-3)" "unprognostic (2.74e-2)" "potential prognostic unfavorable (2.92e-4)" "unprognostic (2.55e-1)" "unprognostic (4.49e-2)" "unprognostic (1.93e-1)" "unprognostic (5.02e-2)" "unprognostic (1.09e-1)" "unprognostic (1.19e-1)" "unprognostic (2.42e-1)" "unprognostic (3.27e-2)" "unprognostic (3.24e-2)" C19orf38 HIDE1 ENSG00000214212 "Chromosome 19 open reading frame 38" A8MVS5 19 10836575-10869790 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "bone marrow: 92.6" "Cell type enhanced" "Detected in many" "cDC: 36.0;Early primary spermatocytes: 38.0;Monocyte progenitors: 45.1;monocytes: 104.3;Neutrophil progenitors: 75.7;Neutrophils: 122.3" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 16.3;leukocyte: 7.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 20 "classical monocyte: 282.7;eosinophil: 169.8;intermediate monocyte: 312.8;myeloid DC: 162.4;neutrophil: 231.0;non-classical monocyte: 394.4" "Group enriched" "Detected in all" 20 "dendritic cells: 162.4;granulocytes: 231.0;monocytes: 394.4" "Group enriched" "Detected in some" 5 "Leukemia: 12.4;lymphoma: 6.1;Myeloma: 5.7" "Breast - Macrophages, Kidney - Macrophages, Lung - Neutrophils_2, Minor Salivary Gland - Macrophages, Spleen - Neutrophils_2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA012150, HPA055027" Uncertain "Golgi apparatus,Plasma membrane,Cytosol" No NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 15: Bone marrow - Innate immune response" "Cluster 30: White matter - Myelination" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 1 Cytosol "Golgi apparatus, Plasma membrane" "HPA012150: , HPA055027: " "unprognostic (1.82e-1)" "unprognostic (4.32e-2)" "unprognostic (4.24e-2)" "potential prognostic favorable (6.29e-7)" "unprognostic (6.33e-2)" "unprognostic (2.43e-1)" "unprognostic (3.60e-1)" "unprognostic (8.12e-2)" "unprognostic (1.84e-2)" "unprognostic (3.86e-2)" "potential prognostic unfavorable (3.97e-4)" "unprognostic (4.71e-2)" "unprognostic (7.28e-2)" "unprognostic (2.57e-1)" "unprognostic (8.90e-2)" "unprognostic (4.07e-2)" "unprognostic (1.74e-1)" "unprognostic (4.57e-2)" "unprognostic (3.77e-1)" "unprognostic (3.08e-1)" "unprognostic (1.97e-1)" "unprognostic (2.72e-1)" "unprognostic (8.93e-2)" "unprognostic (3.11e-1)" "unprognostic (5.47e-3)" "unprognostic (4.27e-1)" "unprognostic (3.58e-3)" "unprognostic (2.38e-1)" "unprognostic (5.92e-2)" "unprognostic (1.14e-2)" "unprognostic (4.31e-2)" C19orf44 FLJ21742 ENSG00000105072 "Chromosome 19 open reading frame 44" Q9H6X5 19 16496394-16521352 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 59.6;Epicardial cells: 31.8;Late spermatids: 127.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041683, HPA049414" Uncertain Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus,Primary cilium,Cytosol" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 21: Testis - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 23: Non-specific - Transcription" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 1 Nucleoplasm "Nuclear bodies, Golgi apparatus, Primary cilium, Cytosol" "HPA041683: , HPA049414: " "unprognostic (2.76e-1)" "unprognostic (1.03e-1)" "potential prognostic favorable (6.11e-5)" "unprognostic (1.80e-1)" "unprognostic (3.53e-2)" "unprognostic (2.13e-1)" "unprognostic (2.49e-1)" "unprognostic (2.32e-1)" "unprognostic (9.14e-2)" "unprognostic (6.39e-2)" "unprognostic (7.40e-3)" "unprognostic (1.79e-3)" "unprognostic (2.85e-1)" "unprognostic (3.37e-2)" "unprognostic (1.84e-1)" "unprognostic (4.50e-2)" "unprognostic (1.61e-1)" "unprognostic (1.35e-1)" "unprognostic (7.96e-3)" "unprognostic (2.50e-1)" "unprognostic (2.18e-1)" "unprognostic (2.67e-2)" "unprognostic (2.69e-2)" "unprognostic (2.49e-3)" "unprognostic (5.75e-2)" "unprognostic (1.52e-1)" "unprognostic (2.05e-2)" "unprognostic (1.04e-1)" "unprognostic (1.27e-1)" "unprognostic (1.23e-1)" "unprognostic (1.21e-2)" C19orf47 FLJ36888 ENSG00000160392 "Chromosome 19 open reading frame 47" Q8N9M1 19 40319536-40348527 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "heart muscle: 164.2;skeletal muscle: 335.4;tongue: 128.4" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 37.0;Late spermatids: 43.7;Thymic myoid cells: 116.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 29.3" "Lineage enriched" "Detected in all" 10 "granulocytes: 29.3" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041843, HPA046309" Uncertain Approved "Nucleoplasm,Nuclear speckles" "Intracellular and membrane" "No annotated function" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 6: Non-specific - Immune response" "Cluster 4: Non-specific - Transcription" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 6 Nucleoplasm "Nuclear speckles" "HPA041843: , HPA046309: " "unprognostic (1.13e-1)" "unprognostic (1.04e-2)" "unprognostic (5.13e-2)" "unprognostic (7.21e-2)" "unprognostic (1.62e-1)" "unprognostic (6.14e-3)" "unprognostic (1.25e-1)" "unprognostic (5.11e-2)" "unprognostic (1.34e-1)" "unprognostic (6.25e-2)" "unprognostic (1.80e-1)" "unprognostic (1.18e-1)" "unprognostic (4.29e-1)" "potential prognostic unfavorable (4.27e-5)" "unprognostic (5.41e-2)" "unprognostic (4.30e-2)" "unprognostic (3.47e-1)" "unprognostic (3.20e-2)" "unprognostic (1.80e-1)" "unprognostic (1.17e-1)" "unprognostic (1.17e-1)" "unprognostic (7.45e-2)" "unprognostic (1.15e-2)" "unprognostic (9.43e-2)" "unprognostic (3.21e-1)" "unprognostic (2.02e-2)" "unprognostic (1.98e-2)" "unprognostic (3.21e-1)" "unprognostic (2.03e-1)" "unprognostic (1.41e-1)" "unprognostic (5.69e-2)" C19orf53 "HSPC023, LYDG10" ENSG00000104979 "Chromosome 19 open reading frame 53" Q9UNZ5 19 13774456-13778773 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 681.5;Esophageal suprabasal cells: 652.1;Late spermatids: 1069.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059928, HPA061291" Approved Approved Nucleoplasm,Nucleoli No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" "Nucleoplasm, Nucleoli" "HPA059928: , HPA061291: " "unprognostic (2.88e-2)" "unprognostic (5.43e-2)" "unprognostic (3.41e-1)" "unprognostic (3.24e-3)" "unprognostic (2.15e-1)" "unprognostic (4.53e-2)" "unprognostic (8.57e-2)" "unprognostic (8.05e-2)" "unprognostic (1.07e-1)" "unprognostic (1.61e-1)" "potential prognostic unfavorable (3.30e-5)" "unprognostic (2.33e-3)" "unprognostic (3.51e-1)" "potential prognostic unfavorable (1.66e-4)" "unprognostic (5.96e-3)" "unprognostic (6.87e-3)" "unprognostic (2.50e-3)" "unprognostic (2.21e-3)" "unprognostic (6.26e-2)" "unprognostic (8.74e-2)" "unprognostic (2.03e-1)" "unprognostic (2.44e-1)" "unprognostic (2.80e-1)" "unprognostic (4.25e-2)" "unprognostic (3.99e-2)" "unprognostic (2.50e-1)" "unprognostic (2.59e-1)" "unprognostic (3.59e-1)" "unprognostic (9.66e-2)" "unprognostic (3.54e-2)" "unprognostic (1.86e-1)" C19orf54 FLJ41131 ENSG00000188493 "Chromosome 19 open reading frame 54" Q5BKX5 19 40740856-40751553 "Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 32.6;Cardiomyocytes: 80.4;Epicardial cells: 113.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059043, HPA059628" Approved Approved "Intermediate filaments,Centriolar satellite" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 49: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 54: Non-specific - Transcription" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "Intermediate filaments" "Centriolar satellite" "HPA059043: , HPA059628: " "unprognostic (1.42e-1)" "unprognostic (1.33e-1)" "unprognostic (3.24e-1)" "unprognostic (1.52e-1)" "unprognostic (1.20e-1)" "unprognostic (5.75e-2)" "unprognostic (3.03e-2)" "unprognostic (1.08e-1)" "unprognostic (1.07e-1)" "unprognostic (4.34e-2)" "unprognostic (1.57e-3)" "potential prognostic unfavorable (1.55e-5)" "unprognostic (1.27e-2)" "unprognostic (9.10e-3)" "unprognostic (1.80e-1)" "unprognostic (4.14e-3)" "unprognostic (3.77e-1)" "unprognostic (5.98e-2)" "unprognostic (4.83e-3)" "unprognostic (2.12e-1)" "unprognostic (8.28e-2)" "unprognostic (1.28e-1)" "unprognostic (4.43e-2)" "unprognostic (7.42e-2)" "unprognostic (2.28e-3)" "unprognostic (2.27e-1)" "unprognostic (1.02e-2)" "unprognostic (2.17e-1)" "unprognostic (2.88e-1)" "unprognostic (1.02e-3)" "unprognostic (2.41e-1)" C19orf67 ENSG00000188032 "Chromosome 19 open reading frame 67" A6NJJ6 19 14081624-14085875 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 28 "testis: 6.4" "Group enriched" "Detected in some" 30 "Early spermatids: 8.0;Late primary spermatocytes: 9.6;Late spermatids: 9.3;Oocytes: 4.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA046351 Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 15: Non-specific - Transcription" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" Cytosol "Nucleoplasm, Nucleoli" "HPA046351: " C19orf73 FLJ10490 ENSG00000221916 "Chromosome 19 open reading frame 73" Q9NVV2 19 49118402-49119143 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 7.1" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 22.7;Esophageal suprabasal cells: 8.7;Tuft cells: 11.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" HPA062719 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 70: Non-specific - Protein processing" "Cluster 37: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" 3 "Nucleoplasm, Cytosol" "HPA062719: " "unprognostic (5.11e-2)" "unprognostic (1.62e-1)" "unprognostic (1.28e-1)" "unprognostic (2.87e-3)" "unprognostic (3.22e-2)" "unprognostic (1.25e-1)" "unprognostic (2.44e-2)" "unprognostic (1.35e-1)" "unprognostic (2.37e-2)" "unprognostic (2.09e-1)" "unprognostic (6.32e-2)" "unprognostic (1.49e-2)" "unprognostic (1.50e-1)" "unprognostic (3.18e-1)" "unprognostic (3.28e-1)" "unprognostic (1.79e-2)" "unprognostic (2.25e-1)" "potential prognostic favorable (9.88e-4)" "unprognostic (1.60e-1)" "unprognostic (4.33e-2)" "unprognostic (1.30e-1)" "unprognostic (1.00e-1)" "unprognostic (1.38e-1)" "unprognostic (1.74e-1)" "unprognostic (2.79e-1)" "unprognostic (1.86e-1)" C19orf81 ENSG00000235034 "Chromosome 19 open reading frame 81" C9J6K1 19 50649445-50659310 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 11 "testis: 6.7" "Cell type enhanced" "Detected in many" "Early spermatids: 25.9;Epididymal clear cells: 28.6;Epididymal efferent duct absorptive cells: 72.9;Epididymal efferent duct ciliated cells: 35.3;Epididymal principal cells: 113.9;Fallopian secretory cells: 27.1;Late primary spermatocytes: 41.9;Müller glia: 30.1;Oocytes: 23.0" "Cell type enhanced" "Detected in many" "upper rhombic lip: 16.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Prostate - Prostate glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA060238 Enhanced Approved Vesicles,Aggresome NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 35: Non-specific - DNA binding" "Cluster 47: Leukemia - Hemostasis" "Cluster 11: Muller glia cells - Retinal homeostasis" "Vesicles, Aggresome" "HPA060238: " "unprognostic (1.43e-1)" "unprognostic (1.72e-1)" C19orf84 ENSG00000262874 "Chromosome 19 open reading frame 84" I3L1E1 19 51388289-51390591 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 31 "testis: 20.6" "Cell type enriched" "Detected in some" 12 "Undifferentiated spermatogonia: 53.4" "Cell type enriched" "Detected in single" 5 "leukocyte: 2.8" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 5.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA068082 Uncertain Approved Vesicles NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 23: Testis - Spermatogenesis" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 106: Spermatogonia - Spermatogonial differentiation" Vesicles "HPA068082: " "unprognostic (1.80e-1)" "unprognostic (1.64e-1)" "unprognostic (7.25e-2)" C19orf85 ENSG00000283567 "Chromosome 19 open reading frame 85" A0A1B0GUS0 19 55463001-55464751 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 100 "Testicular Germ Cell Tumor (TCGA): 63.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "testis cancer: 1.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" "unprognostic (2.17e-1)" C1D "LRP1, Rrp47, SUN-CoR, SUNCOR" ENSG00000197223 "C1D nuclear receptor corepressor" Q13901 2 68041130-68110948 "Predicted intracellular proteins" "Apoptosis, rRNA processing, Transcription, Transcription regulation" "DNA-binding, Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037413, HPA037588" Approved Supported Nucleoplasm,Nucleoli NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 37 "Nucleoplasm, Nucleoli" "HPA037413: , HPA037588: " "unprognostic (1.79e-1)" "unprognostic (5.18e-2)" "unprognostic (2.77e-2)" "unprognostic (5.40e-2)" "unprognostic (1.16e-1)" "unprognostic (1.82e-2)" "unprognostic (5.03e-2)" "unprognostic (1.92e-1)" "unprognostic (4.09e-3)" "unprognostic (2.98e-3)" "validated prognostic favorable (2.28e-6)" "validated prognostic favorable (5.98e-4)" "unprognostic (3.86e-1)" "potential prognostic unfavorable (2.57e-4)" "unprognostic (2.81e-3)" "unprognostic (3.49e-2)" "unprognostic (7.35e-2)" "unprognostic (4.97e-3)" "unprognostic (1.59e-1)" "unprognostic (2.35e-1)" "potential prognostic unfavorable (7.23e-4)" "unprognostic (4.12e-3)" "unprognostic (2.05e-3)" "unprognostic (7.40e-2)" "unprognostic (1.81e-1)" "unprognostic (1.61e-3)" "unprognostic (2.33e-1)" "unprognostic (5.29e-2)" "unprognostic (4.19e-1)" "unprognostic (1.13e-1)" "unprognostic (1.33e-1)" C1GALT1 "C1GALT, T-synthase" ENSG00000106392 "Core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1" Q9NS00 7 7156934-7248616 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Angiogenesis, Differentiation" "Developmental protein, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Choroid plexus epithelial cells: 293.8;Syncytiotrophoblasts: 329.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011294, HPA012819" Enhanced Approved "Nuclear bodies,Cytosol" NA NA 28000 "Cluster 32: Basophils - Transcription" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 67: Non-specific - Unknown function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 2 "Nuclear bodies, Cytosol" "HPA011294: , HPA012819: " "unprognostic (1.34e-1)" "unprognostic (2.46e-1)" "unprognostic (1.73e-1)" "unprognostic (1.51e-3)" "unprognostic (1.75e-1)" "unprognostic (3.63e-2)" "unprognostic (5.65e-3)" "unprognostic (1.95e-1)" "unprognostic (7.17e-3)" "unprognostic (4.03e-2)" "potential prognostic favorable (3.54e-5)" "unprognostic (3.41e-1)" "unprognostic (1.55e-1)" "potential prognostic unfavorable (6.23e-6)" "unprognostic (6.07e-3)" "potential prognostic unfavorable (9.33e-4)" "unprognostic (7.46e-2)" "unprognostic (5.58e-2)" "unprognostic (3.64e-2)" "unprognostic (4.04e-2)" "unprognostic (2.14e-3)" "unprognostic (5.63e-2)" "unprognostic (1.20e-1)" "unprognostic (1.23e-1)" "unprognostic (1.81e-1)" "unprognostic (1.89e-2)" "unprognostic (1.41e-2)" "unprognostic (2.84e-1)" "unprognostic (4.82e-1)" "unprognostic (1.22e-1)" "unprognostic (4.37e-2)" C1GALT1C1 "C1GALT2, COSMC" ENSG00000171155 "C1GALT1 specific chaperone 1" Q96EU7 X 120625674-120630054 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Chaperone "Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 5.6;Bergmann glia: 8.0;Brain excitatory neurons: 8.6;Brain inhibitory neurons: 8.2;Ependymal cells: 9.4;Loop of henle epithelial cells: 5.1;Microglia: 9.2;Oligodendrocyte progenitor cells: 9.6;Oligodendrocytes: 12.5;Other brain neurons: 13.0;Papillary tip epithelial cells: 7.7;Podocytes: 4.9;Renal collecting duct principal cells: 9.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010666, HPA015632" Approved Approved Vesicles NA NA 12000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 98: Neurons - Neurotransmission & signaling" 1 Vesicles "HPA010666: , HPA015632: " "unprognostic (1.51e-2)" "potential prognostic unfavorable (6.95e-4)" "unprognostic (3.03e-2)" "unprognostic (1.26e-1)" "unprognostic (3.81e-2)" "unprognostic (1.37e-1)" "unprognostic (4.68e-3)" "potential prognostic unfavorable (2.05e-4)" "unprognostic (1.41e-2)" "unprognostic (8.05e-3)" "potential prognostic favorable (1.04e-6)" "unprognostic (1.22e-1)" "unprognostic (4.34e-2)" "unprognostic (2.25e-2)" "unprognostic (2.34e-2)" "unprognostic (1.97e-1)" "unprognostic (1.73e-1)" "unprognostic (2.18e-1)" "unprognostic (1.96e-1)" "unprognostic (3.20e-1)" "unprognostic (3.31e-2)" "unprognostic (1.62e-2)" "unprognostic (2.48e-1)" "unprognostic (1.52e-1)" "unprognostic (2.94e-2)" "unprognostic (2.16e-1)" "unprognostic (6.25e-2)" "unprognostic (2.60e-2)" "unprognostic (1.83e-2)" "unprognostic (9.07e-2)" "unprognostic (2.49e-1)" C1GALT1C1L ENSG00000223658 "C1GALT1 specific chaperone 1 like" P0DN25 2 43675151-43676429 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Decidual stromal cells: 19.3;Early primary spermatocytes: 12.6;Endometrial stromal cells: 5.4;Epididymal principal cells: 6.0;Late primary spermatocytes: 17.2;Retinal pigment epithelial cells: 4.3" "Cell type enhanced" "Detected in some" "cerebellar inhibitory: 2.5;committed oligodendrocyte precursor: 2.4;oligodendrocyte: 2.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Pituitary gland - Undifferentiated cells (Pituitary gland), Testis - Early spermatids" NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" "unprognostic (2.13e-1)" "unprognostic (2.41e-1)" "unprognostic (1.25e-1)" "unprognostic (7.69e-3)" "unprognostic (9.34e-2)" "unprognostic (1.75e-1)" "unprognostic (4.61e-2)" "unprognostic (1.63e-2)" "unprognostic (1.53e-1)" "unprognostic (2.09e-2)" "unprognostic (4.37e-1)" "unprognostic (2.06e-1)" "unprognostic (5.23e-2)" "unprognostic (2.73e-1)" "unprognostic (2.15e-2)" C1orf100 ENSG00000173728 "Chromosome 1 open reading frame 100" Q5SVJ3 1 244352635-244389663 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 40 "testis: 21.1" "Group enriched" "Detected in many" 10 "Early spermatids: 1633.4;Late spermatids: 1199.8" "Cell type enriched" "Detected in many" 6 "ependymal cell: 13.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA031179, HPA031180" Approved "Nucleoplasm,Nuclear bodies,Cytosol,Calyx" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 47: Leukemia - Hemostasis" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" Nucleoplasm "Nuclear bodies, Cytosol, Calyx" "HPA031179: , HPA031180: " C1orf105 ENSG00000180999 "Chromosome 1 open reading frame 105" O95561 1 172420685-172468831 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "heart muscle: 16.8;testis: 24.6" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 87.0;Early spermatids: 151.3;Late primary spermatocytes: 269.2" "Cell type enhanced" "Detected in many" "oligodendrocyte precursor cell: 6.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Sarcoma: 11.6" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA079382 Approved Vesicles NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 35: Non-specific - Mixed function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" 6 Vesicles "HPA079382: " "unprognostic (5.74e-2)" "unprognostic (5.43e-2)" "unprognostic (2.56e-1)" C1orf109 FLJ20508 ENSG00000116922 "Chromosome 1 open reading frame 109" Q9NX04 1 37681570-37692249 "Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 41.1;Suprabasal keratinocytes: 44.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027110, HPA027127" Supported Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 26: Keratinocytes - Keratinization" 126 Cytosol "Nucleoplasm, Nucleoli" "HPA027110: , HPA027127: " "unprognostic (2.89e-1)" "unprognostic (4.86e-2)" "potential prognostic unfavorable (3.21e-4)" "unprognostic (8.33e-3)" "unprognostic (9.22e-2)" "unprognostic (2.15e-1)" "unprognostic (1.09e-1)" "unprognostic (5.29e-2)" "unprognostic (6.45e-2)" "unprognostic (2.21e-1)" "potential prognostic favorable (4.00e-6)" "unprognostic (1.47e-2)" "unprognostic (1.94e-1)" "validated prognostic unfavorable (1.71e-4)" "validated prognostic unfavorable (7.76e-5)" "unprognostic (2.03e-1)" "unprognostic (3.31e-2)" "unprognostic (2.61e-1)" "unprognostic (5.21e-3)" "unprognostic (1.21e-1)" "unprognostic (1.09e-2)" "unprognostic (1.49e-1)" "unprognostic (8.42e-2)" "unprognostic (8.18e-2)" "unprognostic (3.42e-2)" "unprognostic (2.51e-1)" "unprognostic (2.10e-2)" "unprognostic (1.75e-1)" "unprognostic (2.15e-1)" "unprognostic (2.49e-2)" "unprognostic (6.30e-2)" C1orf112 FLJ10706 ENSG00000000460 "Chromosome 1 open reading frame 112" Q9NSG2 1 169662007-169854080 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 12.7" "Cell type enhanced" "Detected in many" "Adipocytes: 62.6;Cardiomyocytes: 88.9;Early primary spermatocytes: 77.9;Microglia: 78.1;Thymocytes: 83.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA023778, HPA024451" Uncertain Supported Nucleoplasm,Nucleoli NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 16 Nucleoplasm Nucleoli "HPA023778: , HPA024451: " "unprognostic (3.95e-3)" "unprognostic (9.95e-2)" "unprognostic (3.03e-2)" "unprognostic (7.52e-2)" "unprognostic (3.88e-3)" "unprognostic (9.07e-2)" "unprognostic (1.70e-1)" "unprognostic (2.36e-2)" "unprognostic (3.37e-2)" "unprognostic (1.20e-3)" "unprognostic (1.94e-2)" "unprognostic (1.54e-3)" "unprognostic (1.64e-2)" "validated prognostic unfavorable (2.64e-4)" "validated prognostic unfavorable (1.09e-4)" "unprognostic (7.04e-2)" "unprognostic (2.06e-1)" "unprognostic (3.74e-1)" "unprognostic (2.54e-1)" "validated prognostic unfavorable (2.66e-5)" "validated prognostic unfavorable (1.65e-4)" "unprognostic (8.12e-2)" "unprognostic (2.31e-1)" "unprognostic (3.54e-2)" "unprognostic (1.50e-1)" "unprognostic (1.51e-1)" "unprognostic (1.59e-1)" "unprognostic (3.48e-1)" "unprognostic (6.47e-3)" C1orf115 "FLJ14146, RDD1" ENSG00000162817 "Chromosome 1 open reading frame 115" Q9H7X2 1 220690363-220699153 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 113.9" "Cell type enhanced" "Detected in many" "Colonocytes: 79.0;Cytotrophoblasts: 84.7;Enterocytes: 251.8;Epididymal clear cells: 63.3;Extravillous trophoblasts: 109.7;Hepatocytes: 136.4;Migrating cytotrophoblasts: 88.9;Parietal cells: 120.2;Syncytiotrophoblasts: 245.9" "Cell type enhanced" "Detected in many" "deep-layer near-projecting: 50.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Pituitary gland - Thyrotropes, Prostate - Prostate glandular cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 77: Intestine - Digestion" "Cluster 53: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" "unprognostic (9.99e-3)" "unprognostic (4.29e-2)" "unprognostic (1.07e-1)" "unprognostic (6.62e-3)" "unprognostic (4.39e-3)" "unprognostic (7.25e-2)" "unprognostic (9.65e-2)" "unprognostic (3.54e-1)" "unprognostic (7.28e-2)" "unprognostic (3.68e-3)" "validated prognostic favorable (1.24e-7)" "validated prognostic favorable (1.95e-5)" "unprognostic (3.78e-2)" "unprognostic (1.30e-1)" "unprognostic (3.13e-1)" "unprognostic (3.62e-2)" "unprognostic (2.67e-3)" "potential prognostic favorable (8.31e-4)" "unprognostic (1.72e-2)" "unprognostic (1.04e-2)" "unprognostic (8.72e-2)" "unprognostic (1.32e-1)" "unprognostic (1.85e-1)" "unprognostic (8.42e-2)" "unprognostic (2.29e-2)" "unprognostic (6.73e-3)" "unprognostic (6.25e-2)" "unprognostic (3.36e-1)" "unprognostic (1.94e-1)" "unprognostic (2.30e-2)" "unprognostic (1.61e-3)" C1orf116 "FLJ36507, MGC2742, MGC4309, SARG" ENSG00000182795 "Chromosome 1 open reading frame 116" Q9BW04 1 207018522-207032756 "Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 98.1;lung: 68.8;stomach 1: 55.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 244.4;Esophageal apical cells: 748.6;Esophageal suprabasal cells: 127.9;Foveolar cells: 126.2;Ocular epithelial cells: 379.8;Transitional alveolar cells: 137.1;Urothelial cells: 220.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 118.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 57.3" "Colon - Colon enterocytes, Liver - Cholangiocytes, Minor Salivary Gland - Minor salivary gland basal cells, Pituitary gland - Corticotropes, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA011888, HPA011889" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA 62000 "Cluster 11: Esophagus - Basic cellular processes" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 4 "Plasma membrane, Cytosol" "HPA011888: , HPA011889: " "unprognostic (1.58e-2)" "unprognostic (2.54e-2)" "unprognostic (4.46e-2)" "unprognostic (1.19e-2)" "unprognostic (2.66e-1)" "potential prognostic unfavorable (1.93e-4)" "unprognostic (1.12e-1)" "unprognostic (2.60e-2)" "unprognostic (2.41e-3)" "unprognostic (2.02e-1)" "unprognostic (3.03e-1)" "unprognostic (6.38e-2)" "unprognostic (8.80e-3)" "unprognostic (7.19e-2)" "unprognostic (4.28e-2)" "unprognostic (1.29e-1)" "unprognostic (2.92e-2)" "unprognostic (1.42e-2)" "potential prognostic unfavorable (4.11e-4)" "unprognostic (1.02e-1)" "unprognostic (1.36e-1)" "unprognostic (7.84e-2)" "unprognostic (1.14e-1)" "unprognostic (1.72e-2)" "unprognostic (2.10e-1)" "unprognostic (2.49e-1)" "unprognostic (6.52e-2)" "unprognostic (1.19e-1)" C1orf122 FLJ45459 ENSG00000197982 "Chromosome 1 open reading frame 122" Q6ZSJ8 1 37806979-37809454 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 170.8" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 351.5" "Cell type enhanced" "Detected in all" "oligodendrocyte: 178.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Sebaceous gland cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 27: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 97: Non-specific - Cellular respiration" 5 "unprognostic (7.20e-2)" "unprognostic (1.02e-2)" "unprognostic (9.96e-2)" "unprognostic (2.87e-2)" "unprognostic (4.69e-1)" "unprognostic (1.77e-1)" "unprognostic (1.26e-1)" "unprognostic (3.34e-1)" "unprognostic (9.30e-2)" "unprognostic (3.15e-2)" "validated prognostic unfavorable (1.46e-4)" "validated prognostic unfavorable (4.37e-4)" "unprognostic (9.68e-2)" "potential prognostic unfavorable (1.61e-5)" "unprognostic (1.56e-3)" "unprognostic (8.87e-2)" "unprognostic (6.23e-2)" "unprognostic (8.11e-2)" "unprognostic (2.36e-1)" "unprognostic (1.26e-1)" "unprognostic (3.05e-1)" "unprognostic (3.14e-3)" "unprognostic (1.01e-1)" "unprognostic (3.42e-1)" "unprognostic (9.98e-2)" "unprognostic (9.01e-2)" "unprognostic (1.06e-1)" "unprognostic (1.63e-1)" "unprognostic (3.11e-1)" "unprognostic (6.41e-2)" "unprognostic (1.17e-1)" C1orf127 FLJ37118 ENSG00000175262 "Chromosome 1 open reading frame 127" 1 10946471-10982076 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "pancreas: 4.2;skeletal muscle: 15.7" "Group enriched" "Detected in some" 4 "Myonuclei: 30.7;Neuroendocrine cells: 27.8;Pancreatic islet cells: 34.2" "Group enriched" "Detected in some" 9 "cerebellar inhibitory: 14.9;midbrain-derived inhibitory: 15.6" "Cancer enriched" "Detected in single" 8 "Pancreatic Adenocarcinoma (TCGA): 5.4" "Region enhanced" "Detected in some" "cerebellum: 2.4" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.3" "Lineage enhanced" "Detected in single" "dendritic cells: 1.3" "Cancer enriched" "Detected in some" 5 "Myeloma: 6.0" "Heart muscle - Cardiomyocytes, Pancreas - Beta cells, Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" HPA027654 Uncertain Approved "Nuclear speckles,Cytosol" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" "Nuclear speckles, Cytosol" "HPA027654: " "unprognostic (3.61e-1)" "unprognostic (2.90e-2)" C1orf131 DKFZp547B1713 ENSG00000143633 "Chromosome 1 open reading frame 131" Q8NDD1 1 231223763-231241187 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028452, HPA029920" Enhanced NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 77: Intestine - Digestion" "Cluster 25: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 97: Non-specific - Cellular respiration" 2 "HPA028452: , HPA029920: " "unprognostic (2.19e-1)" "unprognostic (1.25e-1)" "unprognostic (4.12e-1)" "unprognostic (2.51e-1)" "unprognostic (3.84e-2)" "unprognostic (1.82e-2)" "unprognostic (2.84e-1)" "unprognostic (7.98e-2)" "unprognostic (1.24e-1)" "unprognostic (1.09e-1)" "unprognostic (9.44e-2)" "unprognostic (5.43e-2)" "unprognostic (9.05e-2)" "unprognostic (1.97e-2)" "unprognostic (1.28e-1)" "unprognostic (2.82e-3)" "unprognostic (7.10e-2)" "unprognostic (6.95e-2)" "unprognostic (1.93e-1)" "unprognostic (1.26e-2)" "unprognostic (3.47e-2)" "unprognostic (1.05e-1)" "unprognostic (2.06e-1)" "unprognostic (2.73e-1)" "unprognostic (1.03e-1)" "unprognostic (3.43e-3)" "unprognostic (4.20e-2)" "unprognostic (2.78e-1)" "unprognostic (1.34e-1)" "unprognostic (7.94e-2)" "unprognostic (1.97e-1)" C1orf141 ENSG00000203963 "Chromosome 1 open reading frame 141" Q5JVX7 1 67092165-67231853 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "fallopian tube: 8.7;testis: 14.3" "Cell type enhanced" "Detected in many" "Early spermatids: 107.1;Ependymal cells: 51.4;Fallopian tube ciliated cells: 96.0;Granulosa cells: 87.6;Innate lymphoid cells: 32.6;Late primary spermatocytes: 110.6;Late spermatids: 134.7;Müller glia: 56.6;Respiratory ciliated cells: 85.1;Sertoli cells: 87.5" "Cell type enriched" "Detected in some" 8 "ependymal cell: 58.6" "Not detected" "Not detected" "Region enhanced" "Detected in some" "choroid plexus: 5.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA035316 Uncertain "Intermediate filaments" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" "Intermediate filaments" "HPA035316: " C1orf146 SPO16 ENSG00000203910 "Chromosome 1 open reading frame 146" Q5VVC0 1 92217915-92245813 "Predicted intracellular proteins" Meiosis "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 8 "retina: 1.9;testis: 7.0" "Group enriched" "Detected in some" 4 "Early primary spermatocytes: 111.3;Oocytes: 59.9" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Spermatocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA074051 Approved "Centriolar satellite" NA NA "Cluster 47: Testis - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 56: Non-specific - Sensory perception" "Cluster 3: Early primary spermatocytes - Early meiosis" "Centriolar satellite" "HPA074051: " C1orf159 FLJ20584 ENSG00000131591 "Chromosome 1 open reading frame 159" Q96HA4 1 1081818-1116361 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 22.4" "Cell type enhanced" "Detected in many" "Late spermatids: 228.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010019, HPA075399" Approved Approved "Nucleoli rim,Mitotic chromosome,Intermediate filaments" Yes No "Cluster 30: Non-specific - DNA binding" "Cluster 67: Testis - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" "Nucleoli rim, Mitotic chromosome" "Intermediate filaments" "HPA010019: , HPA075399: " "unprognostic (4.71e-2)" "unprognostic (4.50e-3)" "unprognostic (2.19e-1)" "unprognostic (7.83e-2)" "unprognostic (8.06e-2)" "unprognostic (5.25e-3)" "unprognostic (7.58e-2)" "unprognostic (2.98e-2)" "unprognostic (1.74e-2)" "potential prognostic unfavorable (5.74e-4)" "potential prognostic unfavorable (8.18e-5)" "unprognostic (1.01e-2)" "unprognostic (4.93e-1)" "potential prognostic unfavorable (1.59e-7)" "unprognostic (2.19e-2)" "unprognostic (2.78e-3)" "unprognostic (1.11e-1)" "unprognostic (5.97e-2)" "unprognostic (2.97e-1)" "unprognostic (6.72e-2)" "unprognostic (7.25e-3)" "unprognostic (6.42e-2)" "unprognostic (9.81e-3)" "unprognostic (1.06e-1)" "unprognostic (1.59e-1)" "unprognostic (3.74e-2)" "unprognostic (1.16e-1)" "unprognostic (2.97e-2)" "unprognostic (2.66e-2)" "unprognostic (5.85e-2)" "unprognostic (1.99e-1)" C1orf162 MGC24133 ENSG00000143110 "Chromosome 1 open reading frame 162" Q8NEQ5 1 111473792-111478512 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 108.7;lymphoid tissue: 151.3" "Cell type enhanced" "Detected in many" "cDC: 418.4;Kupffer cells: 867.1;Late spermatids: 138.2;Macrophages: 337.8;Mast cells: 195.8;Monocyte progenitors: 210.1;monocytes: 532.3;Neutrophil progenitors: 174.9;Neutrophils: 472.2" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 24.0;leukocyte: 30.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in some" 6 "Leukemia: 22.5" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Minor Salivary Gland - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Stomach - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA026988 Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" "Nucleoplasm, Golgi apparatus" "HPA026988: " "unprognostic (2.78e-1)" "unprognostic (1.38e-1)" "unprognostic (8.94e-3)" "unprognostic (5.00e-3)" "unprognostic (5.55e-2)" "unprognostic (1.23e-1)" "unprognostic (1.77e-2)" "unprognostic (7.04e-2)" "unprognostic (1.30e-1)" "unprognostic (2.88e-1)" "unprognostic (2.11e-2)" "unprognostic (3.00e-1)" "unprognostic (2.04e-1)" "unprognostic (1.10e-1)" "unprognostic (2.32e-2)" "unprognostic (9.21e-2)" "unprognostic (4.51e-2)" "unprognostic (6.44e-2)" "unprognostic (3.78e-1)" "unprognostic (1.31e-1)" "unprognostic (3.09e-1)" "unprognostic (1.22e-1)" "unprognostic (6.10e-2)" "unprognostic (2.20e-1)" "unprognostic (4.93e-2)" "unprognostic (1.26e-2)" "unprognostic (7.46e-2)" "unprognostic (4.24e-2)" "unprognostic (8.30e-3)" "unprognostic (5.38e-2)" "unprognostic (2.61e-1)" C1orf167 "DKFZp434E1410, RP11-56N19.2" ENSG00000215910 "Chromosome 1 open reading frame 167" Q5SNV9 1 11761787-11789585 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 24 "testis: 13.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 80.1;Alveolar cells type 2: 36.1;Breast lactating cells: 24.2;Cardiomyocytes: 99.9;Epicardial cells: 66.0;Esophageal apical cells: 28.8;Late primary spermatocytes: 39.2;Late spermatids: 30.9;Myosatellite cells: 28.3;Oocytes: 69.1;Thymic myoid cells: 31.3" "Cell type enhanced" "Detected in some" "pericyte: 4.2;vascular associated smooth muscle cell: 3.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "lymphoma: 1.3;Myeloma: 1.2" "Testis - Early spermatids" HPA039114 Enhanced NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 81: Alveolar cells - Lung function" "HPA039114: " "unprognostic (4.93e-1)" "unprognostic (1.19e-1)" C1orf174 RP13-531C17.2 ENSG00000198912 "Chromosome 1 open reading frame 174" Q8IYL3 1 3889125-3900293 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 68.3;Early spermatids: 162.5;Extravillous trophoblasts: 74.2;Migrating cytotrophoblasts: 74.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008270, HPA065778" Approved Enhanced Nucleoplasm NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 24: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 37: Non-specific - mRNA processing" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 25 Nucleoplasm "HPA008270: , HPA065778: " "unprognostic (3.79e-2)" "unprognostic (2.98e-1)" "unprognostic (1.63e-1)" "unprognostic (3.80e-3)" "unprognostic (4.88e-2)" "unprognostic (3.12e-1)" "unprognostic (2.29e-1)" "unprognostic (5.51e-2)" "unprognostic (3.38e-2)" "unprognostic (3.69e-3)" "unprognostic (9.31e-2)" "unprognostic (2.69e-2)" "unprognostic (6.57e-2)" "validated prognostic unfavorable (1.42e-5)" "validated prognostic unfavorable (7.85e-6)" "unprognostic (2.76e-1)" "potential prognostic unfavorable (7.31e-4)" "unprognostic (1.10e-1)" "unprognostic (1.67e-1)" "unprognostic (1.14e-1)" "unprognostic (4.86e-2)" "potential prognostic unfavorable (3.30e-4)" "unprognostic (8.53e-2)" "unprognostic (2.19e-1)" "unprognostic (2.12e-1)" "unprognostic (2.13e-2)" "unprognostic (2.32e-2)" "unprognostic (3.08e-2)" "unprognostic (2.83e-1)" "unprognostic (7.47e-2)" "unprognostic (2.86e-1)" C1orf185 FLJ27485 ENSG00000204006 "Chromosome 1 open reading frame 185" Q5T7R7 1 51102221-51148086 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 139 "testis: 23.7" "Group enriched" "Detected in some" 10 "Early spermatids: 674.1;Late primary spermatocytes: 419.9" "Cell type enhanced" "Detected in some" "Bergmann glia: 2.8;oligodendrocyte precursor cell: 8.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 38: Non-specific - Transcription" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" C1orf198 "DKFZp667D152, FLJ14525, FLJ16283, FLJ38847, MGC10710" ENSG00000119280 "Chromosome 1 open reading frame 198" Q9H425 1 230837119-230869589 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 144.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 143.4;Ependymal cells: 140.0;Hepatic stellate cells: 103.3;Melanocytes: 78.5;Oligodendrocytes: 86.6;Platelets: 167.9;Schwann cells: 112.2;Thymic myoid cells: 110.1" "Cell type enhanced" "Detected in many" "astrocyte: 109.8;ependymal cell: 167.3;oligodendrocyte: 120.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 13.1" "Lineage enriched" "Detected in all" 4 "granulocytes: 13.1" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Smooth muscle cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004798 Approved Supported Cytosol NA NA 39000 "Cluster 14: Non-specific - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 61: Schwann cells & Melanocytes - Mixed function" 4 Cytosol "HPA004798: " "unprognostic (3.66e-3)" "unprognostic (4.36e-2)" "unprognostic (1.46e-1)" "unprognostic (1.71e-1)" "unprognostic (1.98e-2)" "unprognostic (2.06e-1)" "unprognostic (2.14e-1)" "unprognostic (9.05e-3)" "unprognostic (1.52e-1)" "unprognostic (2.60e-2)" "potential prognostic favorable (6.73e-4)" "unprognostic (2.17e-2)" "potential prognostic unfavorable (3.04e-4)" "unprognostic (1.09e-1)" "unprognostic (1.98e-1)" "unprognostic (1.33e-1)" "unprognostic (2.48e-1)" "unprognostic (3.67e-3)" "unprognostic (1.31e-1)" "unprognostic (1.12e-1)" "unprognostic (2.91e-2)" "unprognostic (7.96e-2)" "unprognostic (1.14e-1)" "unprognostic (6.30e-2)" "unprognostic (1.39e-2)" "unprognostic (1.39e-1)" "unprognostic (2.72e-1)" "unprognostic (1.50e-1)" "unprognostic (1.08e-1)" "unprognostic (3.66e-2)" "unprognostic (1.09e-1)" C1orf21 PIG13 ENSG00000116667 "Chromosome 1 open reading frame 21" Q9H246 1 184387029-184629019 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 36.2" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 618.1;Myonuclei: 1766.3;Pituicytes/FSCs: 726.6;Syncytiotrophoblasts: 615.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "gdT-cell: 3.9;memory CD8 T-cell: 2.0;naive CD8 T-cell: 1.8;NK-cell: 2.6" "Group enriched" "Detected in many" 13 "NK-cells: 2.6;T-cells: 3.9" "Cancer enhanced" "Detected in many" "Neuroblastoma: 11.7" "Low region specificity" "Detected in all" HPA026831 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 24: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 55: Myocytes - Oxidative muscle function" 8 "Nucleoplasm, Cytosol" "HPA026831: " "unprognostic (1.17e-1)" "unprognostic (8.98e-2)" "unprognostic (1.56e-1)" "unprognostic (9.86e-2)" "unprognostic (8.32e-2)" "unprognostic (8.40e-2)" "unprognostic (3.90e-2)" "unprognostic (2.60e-2)" "unprognostic (3.93e-3)" "unprognostic (4.48e-2)" "unprognostic (3.07e-1)" "unprognostic (3.54e-2)" "unprognostic (2.06e-2)" "unprognostic (4.32e-3)" "unprognostic (5.10e-2)" "unprognostic (1.34e-1)" "unprognostic (2.14e-1)" "unprognostic (9.43e-2)" "unprognostic (4.22e-1)" "unprognostic (1.73e-2)" "unprognostic (6.59e-2)" "unprognostic (8.31e-2)" "unprognostic (1.08e-1)" "unprognostic (2.09e-2)" "unprognostic (3.88e-1)" "unprognostic (4.67e-2)" "unprognostic (2.20e-1)" C1orf210 "MGC52423, TEMP" ENSG00000253313 "Chromosome 1 open reading frame 210" Q8IVY1 1 43281877-43285617 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 41.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 43.9;Breast lactating cells: 92.1;Colonocytes: 107.2;Enteric transient amplifying cells: 47.3;Enterocytes: 121.2;Esophageal apical cells: 160.2;Esophageal suprabasal cells: 49.6;Foveolar cells: 46.1;Goblet cells: 42.8;Parietal cells: 56.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 14 "basophil: 2.2" "Lineage enriched" "Detected in single" 14 "granulocytes: 2.2" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Colon - Colon enterocytes, Liver - Hepatocytes, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA013788 Uncertain Uncertain "Nucleoli,Nucleoli rim" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 60: Stomach - Digestion" "Cluster 6: Non-specific - Immune response" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 13 "Nucleoli, Nucleoli rim" "HPA013788: " "unprognostic (7.35e-2)" "unprognostic (1.97e-1)" "unprognostic (6.86e-2)" "unprognostic (1.18e-1)" "unprognostic (2.11e-1)" "unprognostic (1.08e-1)" "unprognostic (8.59e-2)" "unprognostic (1.05e-2)" "validated prognostic favorable (1.22e-12)" "validated prognostic favorable (4.84e-4)" "potential prognostic favorable (5.48e-7)" "unprognostic (1.70e-1)" "unprognostic (1.33e-2)" "unprognostic (1.14e-2)" "unprognostic (2.32e-2)" "unprognostic (1.33e-1)" "unprognostic (2.15e-1)" "unprognostic (9.30e-2)" "unprognostic (7.29e-2)" "unprognostic (3.47e-1)" "unprognostic (1.02e-2)" "unprognostic (3.56e-2)" "unprognostic (2.66e-1)" "unprognostic (2.18e-2)" "unprognostic (1.90e-1)" "unprognostic (3.64e-2)" "unprognostic (1.45e-1)" "unprognostic (1.38e-1)" "unprognostic (3.96e-1)" C1orf216 FLJ38984 ENSG00000142686 "Chromosome 1 open reading frame 216" Q8TAB5 1 35713877-35718894 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 76.4" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 19.2;Hepatic stellate cells: 19.4;Late primary spermatocytes: 24.8;Other brain neurons: 19.8;Peritubular myoid cells: 18.4;Retinal amacrine cells: 19.1;Retinal horizontal cells: 22.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028299, HPA031343" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 35: Neurons - Synaptic function & neurogenesis" 71 "Nucleoplasm, Cytosol" "HPA028299: , HPA031343: " "unprognostic (6.55e-3)" "unprognostic (2.04e-1)" "unprognostic (1.14e-2)" "unprognostic (3.28e-1)" "unprognostic (1.51e-1)" "unprognostic (6.22e-2)" "unprognostic (2.40e-1)" "unprognostic (7.57e-2)" "unprognostic (1.35e-1)" "unprognostic (5.67e-3)" "unprognostic (9.41e-3)" "unprognostic (2.21e-1)" "unprognostic (2.38e-2)" "potential prognostic unfavorable (3.78e-4)" "unprognostic (2.38e-2)" "unprognostic (9.83e-3)" "unprognostic (1.98e-1)" "unprognostic (1.19e-1)" "unprognostic (6.09e-3)" "unprognostic (4.12e-2)" "unprognostic (2.50e-1)" "unprognostic (1.90e-2)" "unprognostic (9.39e-2)" "unprognostic (6.05e-2)" "unprognostic (2.68e-1)" "potential prognostic favorable (9.55e-4)" "unprognostic (1.26e-1)" "unprognostic (3.07e-1)" "unprognostic (2.84e-1)" "unprognostic (1.10e-1)" "unprognostic (2.04e-1)" C1orf226 FLJ13137 ENSG00000239887 "Chromosome 1 open reading frame 226" A1L170 1 162378841-162386812 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 20.8" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 31.9;Bergmann glia: 26.7;Early spermatids: 29.1;Hepatocytes: 32.1;Late spermatids: 62.1" "Cell type enhanced" "Detected in many" "Bergmann glia: 24.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "HPA052251, HPA074060" Approved Approved Nucleoplasm NA NA "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 4 Nucleoplasm "HPA052251: , HPA074060: " "unprognostic (1.37e-1)" "potential prognostic favorable (4.90e-4)" "unprognostic (3.82e-1)" "unprognostic (5.90e-2)" "unprognostic (7.60e-2)" "unprognostic (8.01e-3)" "unprognostic (1.13e-2)" "unprognostic (1.90e-1)" "unprognostic (6.24e-2)" "unprognostic (1.59e-2)" "potential prognostic favorable (2.00e-5)" "unprognostic (3.66e-3)" "unprognostic (1.34e-1)" "unprognostic (3.26e-1)" "unprognostic (1.05e-1)" "unprognostic (5.64e-2)" "unprognostic (1.79e-1)" "potential prognostic favorable (3.49e-4)" "unprognostic (1.42e-1)" "unprognostic (2.34e-1)" "unprognostic (2.67e-1)" "unprognostic (1.07e-2)" "unprognostic (8.06e-2)" "unprognostic (6.57e-3)" "unprognostic (3.85e-2)" "unprognostic (2.85e-2)" "unprognostic (2.17e-2)" "unprognostic (1.59e-1)" "unprognostic (2.02e-1)" "unprognostic (2.36e-1)" C1orf232 ENSG00000282872 "Chromosome 1 open reading frame 230" A0A0U1RR37 1 26164101-26168963 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Epididymal principal cells: 6.1;Late spermatids: 1.0;Müller glia: 3.5;Oocytes: 4.6;Retinal amacrine cells: 3.9;Retinal bipolar cells: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 4 "cerebellum: 1.6" "Not detected" "Not detected" NA NA "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 11: Neuronal - Sensory perception" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" C1orf35 "MGC4174, MMTAG2" ENSG00000143793 "Chromosome 1 open reading frame 35" Q9BU76 1 228100726-228105411 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046175 Approved Approved "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 54: Non-specific - Ribosome" "Cluster 37: Neurons - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 65: Non-specific - Cell growth & division" 52 "Nuclear speckles, Plasma membrane" Cytosol "HPA046175: " "unprognostic (2.96e-2)" "unprognostic (6.95e-2)" "unprognostic (2.37e-1)" "unprognostic (2.65e-1)" "unprognostic (2.08e-1)" "unprognostic (1.90e-2)" "unprognostic (5.87e-2)" "unprognostic (2.94e-3)" "unprognostic (1.35e-1)" "unprognostic (3.91e-1)" "unprognostic (4.86e-2)" "unprognostic (6.80e-2)" "unprognostic (8.97e-3)" "unprognostic (3.40e-3)" "unprognostic (2.70e-2)" "unprognostic (1.31e-1)" "unprognostic (4.67e-2)" "unprognostic (9.47e-2)" "unprognostic (2.25e-2)" "potential prognostic favorable (4.95e-4)" "unprognostic (4.75e-2)" "unprognostic (9.66e-2)" "potential prognostic unfavorable (5.43e-4)" "unprognostic (3.82e-2)" "unprognostic (8.70e-3)" "unprognostic (1.24e-1)" "unprognostic (2.81e-2)" "unprognostic (9.53e-2)" "unprognostic (2.36e-2)" "unprognostic (1.65e-1)" "unprognostic (2.00e-1)" C1orf43 "DKFZp586G1722, NICE-3" ENSG00000143612 "Chromosome 1 open reading frame 43" Q9BWL3 1 154206696-154220637 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010725 Approved Supported Mitochondria,Cytosol NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 97: Non-specific - Cellular respiration" 2 Mitochondria Cytosol "HPA010725: " "unprognostic (2.56e-1)" "unprognostic (1.64e-2)" "unprognostic (6.02e-2)" "unprognostic (3.64e-3)" "unprognostic (1.43e-1)" "unprognostic (1.66e-1)" "unprognostic (2.77e-1)" "unprognostic (1.38e-1)" "unprognostic (7.15e-3)" "unprognostic (2.08e-3)" "potential prognostic favorable (2.93e-7)" "unprognostic (4.48e-3)" "unprognostic (1.33e-2)" "unprognostic (1.42e-3)" "unprognostic (9.57e-2)" "unprognostic (6.35e-2)" "unprognostic (5.71e-2)" "unprognostic (9.70e-2)" "unprognostic (1.24e-1)" "unprognostic (4.16e-2)" "unprognostic (5.15e-2)" "unprognostic (6.00e-2)" "unprognostic (2.97e-1)" "unprognostic (9.85e-2)" "unprognostic (2.69e-2)" "unprognostic (9.61e-2)" "unprognostic (1.85e-1)" "unprognostic (1.29e-1)" "unprognostic (1.54e-1)" "unprognostic (2.75e-1)" "unprognostic (1.62e-1)" C1orf50 MGC955 ENSG00000164008 "Chromosome 1 open reading frame 50" Q9BV19 1 42767245-42779491 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in single" "Late spermatids: 1.7" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030236 Uncertain NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Ribosome" "Cluster 37: Non-specific - mRNA processing" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 14 "HPA030236: " "unprognostic (4.71e-3)" "unprognostic (2.78e-3)" "unprognostic (1.72e-3)" "unprognostic (2.15e-1)" "unprognostic (3.05e-1)" "unprognostic (1.53e-1)" "unprognostic (1.39e-1)" "unprognostic (3.77e-3)" "unprognostic (1.16e-2)" "unprognostic (9.81e-3)" "validated prognostic favorable (1.59e-6)" "validated prognostic favorable (1.18e-4)" "unprognostic (4.26e-2)" "unprognostic (6.97e-2)" "unprognostic (8.13e-2)" "unprognostic (1.80e-1)" "unprognostic (1.00e-1)" "unprognostic (9.35e-3)" "unprognostic (1.75e-1)" "unprognostic (2.05e-1)" "unprognostic (8.08e-3)" "unprognostic (4.07e-1)" "unprognostic (2.22e-1)" "unprognostic (4.63e-2)" "unprognostic (3.44e-2)" "unprognostic (3.93e-2)" "unprognostic (3.00e-2)" "unprognostic (3.48e-1)" "unprognostic (7.69e-2)" "unprognostic (2.04e-1)" C1orf52 "FLJ44982, gm117" ENSG00000162642 "Chromosome 1 open reading frame 52" Q8N6N3 1 85249953-85259672 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036072, HPA061790" Approved Enhanced Nucleoplasm NA NA "Cluster 32: Basophils - Transcription" "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 2 Nucleoplasm "HPA036072: , HPA061790: " "unprognostic (1.00e-1)" "unprognostic (1.60e-2)" "unprognostic (9.91e-2)" "unprognostic (8.68e-2)" "unprognostic (1.09e-3)" "unprognostic (1.54e-1)" "unprognostic (8.24e-3)" "unprognostic (6.16e-3)" "unprognostic (3.98e-2)" "unprognostic (1.06e-2)" "unprognostic (3.09e-3)" "unprognostic (4.64e-2)" "unprognostic (6.35e-2)" "potential prognostic unfavorable (1.94e-5)" "unprognostic (5.72e-3)" "unprognostic (1.23e-1)" "unprognostic (8.29e-2)" "unprognostic (2.65e-3)" "unprognostic (3.33e-2)" "unprognostic (9.06e-2)" "unprognostic (9.24e-2)" "unprognostic (2.72e-2)" "potential prognostic unfavorable (9.06e-7)" "unprognostic (5.10e-2)" "unprognostic (5.78e-2)" "unprognostic (2.06e-1)" "unprognostic (7.48e-2)" "unprognostic (3.33e-2)" "unprognostic (3.54e-2)" "unprognostic (1.61e-1)" "unprognostic (2.29e-1)" C1orf53 ENSG00000203724 "Chromosome 1 open reading frame 53" Q5VUE5 1 197902630-197907367 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 15.4" "Cell type enhanced" "Detected in many" "Epididymal clear cells: 32.7;Hepatocytes: 72.5;Oocytes: 64.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 9.0" "Lineage enriched" "Detected in many" 4 "monocytes: 9.0" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065352 Approved Vesicles,Aggresome NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 70: Non-specific - Protein processing" "Cluster 23: Choroid plexus - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 97: Non-specific - Cellular respiration" Vesicles Aggresome "HPA065352: " "unprognostic (1.63e-2)" "unprognostic (2.09e-3)" "unprognostic (1.86e-2)" "unprognostic (5.08e-2)" "unprognostic (4.20e-3)" "unprognostic (7.74e-2)" "unprognostic (2.23e-1)" "unprognostic (9.19e-2)" "unprognostic (1.07e-1)" "unprognostic (3.25e-1)" "validated prognostic unfavorable (2.36e-8)" "validated prognostic unfavorable (1.90e-6)" "unprognostic (7.02e-2)" "unprognostic (2.68e-2)" "unprognostic (4.40e-2)" "unprognostic (2.32e-2)" "unprognostic (8.86e-2)" "unprognostic (8.55e-2)" "unprognostic (1.56e-1)" "unprognostic (9.42e-2)" "unprognostic (2.09e-1)" "unprognostic (2.43e-1)" "unprognostic (7.15e-2)" "unprognostic (4.54e-1)" "unprognostic (1.84e-1)" "unprognostic (1.43e-2)" "unprognostic (2.73e-2)" "unprognostic (1.15e-1)" "unprognostic (1.45e-1)" "potential prognostic unfavorable (7.60e-4)" "unprognostic (1.76e-3)" C1orf54 FLJ23221 ENSG00000118292 "Chromosome 1 open reading frame 54" Q8WWF1 1 150268200-150280916 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "cDC: 211.2;Kupffer cells: 324.9;Leydig cells: 106.3;Peritubular myoid cells: 129.2" "Cell type enhanced" "Detected in all" "endothelial cell: 110.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "myeloid DC: 103.8" "Lineage enriched" "Detected in many" 5 "dendritic cells: 103.8" "Cancer enhanced" "Detected in all" "Rhabdoid: 36.3" "Minor Salivary Gland - Endothelial cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026518, HPA043874" Approved Approved "Plasma membrane" "Secreted to blood" "No annotated function" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 44: Non-specific - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 82: Dendritic cells - Antigen presentation" 37 "Plasma membrane" "HPA026518: , HPA043874: " "unprognostic (4.68e-2)" "unprognostic (1.93e-2)" "unprognostic (1.94e-1)" "unprognostic (1.13e-1)" "unprognostic (2.10e-3)" "unprognostic (5.45e-2)" "unprognostic (9.42e-2)" "unprognostic (7.56e-3)" "unprognostic (1.23e-1)" "unprognostic (1.38e-1)" "unprognostic (6.27e-2)" "unprognostic (2.10e-3)" "unprognostic (1.41e-1)" "unprognostic (1.24e-2)" "unprognostic (3.28e-1)" "unprognostic (1.92e-1)" "potential prognostic unfavorable (5.07e-4)" "unprognostic (1.11e-1)" "unprognostic (1.12e-1)" "unprognostic (1.64e-1)" "unprognostic (1.32e-1)" "unprognostic (1.31e-1)" "unprognostic (1.39e-1)" "unprognostic (2.03e-1)" "unprognostic (4.07e-2)" "unprognostic (3.02e-2)" "unprognostic (1.01e-1)" "unprognostic (8.08e-2)" "unprognostic (1.89e-1)" "unprognostic (1.03e-2)" "unprognostic (3.65e-2)" C1orf56 "FLJ20519, MENT" ENSG00000143443 "Chromosome 1 open reading frame 56" Q9BUN1 1 151047751-151051986 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "testis: 71.9" "Cell type enhanced" "Detected in many" "Early spermatids: 412.2;Late primary spermatocytes: 751.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA037429, HPA037430" Enhanced "Secreted to blood" "No annotated function" NA NA 8100000 "Cluster 32: Basophils - Transcription" "Cluster 79: Testis - Spermatogenesis" "Cluster 25: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 3 "HPA037429: , HPA037430: " "unprognostic (3.86e-1)" "unprognostic (1.62e-1)" "unprognostic (1.65e-1)" "unprognostic (3.87e-1)" "unprognostic (1.32e-1)" "unprognostic (2.30e-1)" "unprognostic (5.20e-2)" "unprognostic (1.02e-1)" "unprognostic (4.29e-2)" "unprognostic (2.98e-2)" "unprognostic (6.84e-2)" "unprognostic (6.75e-3)" "unprognostic (3.74e-3)" "unprognostic (1.38e-2)" "unprognostic (5.26e-2)" "unprognostic (1.72e-1)" "unprognostic (1.11e-1)" "unprognostic (1.38e-2)" "unprognostic (9.53e-2)" "unprognostic (2.24e-2)" "unprognostic (2.07e-1)" "unprognostic (6.41e-3)" "unprognostic (4.70e-2)" "unprognostic (8.93e-2)" "unprognostic (9.13e-2)" "unprognostic (6.01e-2)" "unprognostic (7.83e-2)" "unprognostic (1.62e-2)" "unprognostic (1.05e-1)" "unprognostic (1.66e-1)" "unprognostic (1.14e-1)" C1orf68 "LEP7, XP32" ENSG00000198854 "Chromosome 1 open reading frame 68" Q5T750 1 152719522-152720470 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "skin 1: 639.5" "Cell type enriched" "Detected in some" 25 "Suprabasal keratinocytes: 27.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 15 "Head and Neck Squamous Cell Carcinoma (TCGA): 3.7;Skin Cutaneous Melanoma (TCGA): 12.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Not detected" "Not detected" HPA057942 Approved "Plasma membrane,Cytosol" NA NA 190000 "Cluster 37: Skin - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 26: Keratinocytes - Keratinization" 1 "Plasma membrane" Cytosol "HPA057942: " "unprognostic (7.07e-2)" "unprognostic (4.75e-2)" C1orf74 "FLJ25078, URLC4" ENSG00000162757 "Chromosome 1 open reading frame 74" Q96LT6 1 209779208-209784559 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 6.4" "Cell type enhanced" "Detected in some" "Endometrial glandular cells: 4.4;Endometrial luminal cells: 9.8;Epididymal basal cells: 6.8;Epididymal clear cells: 4.1;Esophageal basal cells: 3.7;Esophageal suprabasal cells: 5.2;Oocytes: 4.6;Suprabasal keratinocytes: 3.7;Urothelial cells: 4.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028496 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 58: Skin - Keratinization" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 51: Secretory epithelial cells - Mixed function" 5 "Plasma membrane, Cytosol" "HPA028496: " "unprognostic (1.03e-1)" "unprognostic (1.59e-1)" "unprognostic (8.16e-2)" "potential prognostic unfavorable (9.77e-6)" "unprognostic (4.08e-2)" "unprognostic (1.38e-1)" "unprognostic (2.94e-1)" "unprognostic (1.31e-2)" "unprognostic (3.47e-1)" "potential prognostic favorable (6.17e-5)" "unprognostic (1.12e-3)" "unprognostic (5.44e-2)" "unprognostic (4.65e-2)" "unprognostic (3.52e-1)" "unprognostic (2.16e-1)" "unprognostic (1.31e-2)" "unprognostic (2.81e-1)" "unprognostic (1.43e-1)" "unprognostic (7.00e-2)" "unprognostic (3.57e-2)" "unprognostic (2.13e-1)" "unprognostic (2.86e-1)" "unprognostic (2.60e-1)" "unprognostic (1.09e-1)" "unprognostic (1.37e-1)" "unprognostic (9.69e-2)" "unprognostic (1.57e-1)" "unprognostic (1.48e-1)" "unprognostic (2.79e-2)" "unprognostic (1.71e-1)" C1orf87 "CREF, MGC34837" ENSG00000162598 "Chromosome 1 open reading frame 87" Q8N0U7 1 59987269-60073770 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "fallopian tube: 28.2" "Group enriched" "Detected in some" 5 "Early spermatids: 77.4;Endometrial ciliated cells: 115.8;Ependymal cells: 262.8;Epididymal efferent duct ciliated cells: 95.3;Fallopian tube ciliated cells: 184.8;Late primary spermatocytes: 135.1;Respiratory ciliated cells: 303.9" "Cell type enriched" "Detected in some" 9 "ependymal cell: 315.9" "Cancer enhanced" "Detected in some" "Lung Adenocarcinoma (TCGA): 1.2;Uterine Corpus Endometrial Carcinoma (TCGA): 1.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA031366, HPA031368" Enhanced NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" "HPA031366: , HPA031368: " "unprognostic (8.04e-2)" "unprognostic (2.99e-1)" "unprognostic (2.17e-1)" C1orf94 MGC15882 ENSG00000142698 "Chromosome 1 open reading frame 94" Q6P1W5 1 34166883-34219131 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 26 "testis: 18.3" "Group enriched" "Detected in some" 14 "Early spermatids: 84.6;Late primary spermatocytes: 107.8;Late spermatids: 44.6" "Low cell type specificity" "Detected in some" "Cancer enriched" "Detected in single" 9 "Glioblastoma Multiforme (TCGA): 3.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 1.8;lymphoma: 1.5" "Skin - Inner root sheath cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA045805 Approved Nucleoplasm,Cytosol NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 22: Non-specific - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 89 Cytosol Nucleoplasm "HPA045805: " "unprognostic (3.15e-1)" "unprognostic (4.16e-3)" C1QA ENSG00000173372 "Complement C1q A chain" P02745 1 22635077-22639678 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement pathway, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 604.1;lymphoid tissue: 1056.2" "Group enriched" "Detected in some" 8 "Kupffer cells: 45.1;Macrophages: 34.6;Microglia: 131.3" "Cell type enriched" "Detected in some" 24 "central nervous system macrophage: 167.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 38 "intermediate monocyte: 227.9;non-classical monocyte: 184.6" "Lineage enriched" "Detected in many" 59 "monocytes: 227.9" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Spleen - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002350, CAB009823" Supported "Secreted to blood" "Complement pathway" NA NA 4400000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 1: Neuronal - Visual perception" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 7 "CAB009823: , HPA002350: " "unprognostic (1.90e-1)" "unprognostic (1.06e-1)" "unprognostic (2.65e-1)" "unprognostic (1.23e-2)" "unprognostic (3.35e-2)" "unprognostic (6.59e-2)" "unprognostic (2.63e-2)" "unprognostic (2.40e-1)" "unprognostic (3.10e-1)" "unprognostic (1.06e-1)" "unprognostic (2.25e-3)" "unprognostic (1.90e-1)" "unprognostic (1.94e-1)" "unprognostic (1.95e-1)" "unprognostic (5.94e-2)" "unprognostic (3.15e-1)" "unprognostic (7.16e-2)" "unprognostic (8.79e-2)" "unprognostic (8.23e-2)" "unprognostic (7.50e-2)" "unprognostic (1.62e-1)" "unprognostic (6.03e-2)" "unprognostic (6.34e-2)" "unprognostic (1.33e-1)" "unprognostic (1.02e-1)" "unprognostic (5.51e-2)" "unprognostic (4.67e-2)" "unprognostic (1.74e-1)" "unprognostic (2.04e-3)" "unprognostic (7.68e-2)" "unprognostic (2.46e-1)" C1QB ENSG00000173369 "Complement C1q B chain" 1 22652762-22661637 "Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 1405.0" "Group enriched" "Detected in many" 9 "Hofbauer cells: 2336.0;Kupffer cells: 7919.5;Macrophages: 2524.3" "Cell type enriched" "Detected in many" 32 "central nervous system macrophage: 378.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 71 "intermediate monocyte: 142.5;non-classical monocyte: 103.0" "Lineage enriched" "Detected in many" 83 "monocytes: 142.5" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Spleen - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052116 Approved "Secreted to blood" "Complement pathway" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 1 "HPA052116: " "unprognostic (1.90e-1)" "unprognostic (1.30e-1)" "unprognostic (3.59e-1)" "unprognostic (4.65e-3)" "unprognostic (1.32e-1)" "unprognostic (4.99e-3)" "unprognostic (1.31e-2)" "unprognostic (3.58e-1)" "unprognostic (2.33e-1)" "unprognostic (3.27e-1)" "unprognostic (3.30e-3)" "unprognostic (2.12e-1)" "unprognostic (2.56e-1)" "unprognostic (8.72e-2)" "unprognostic (3.08e-2)" "unprognostic (3.42e-1)" "unprognostic (5.17e-2)" "unprognostic (6.79e-2)" "unprognostic (5.04e-2)" "unprognostic (5.14e-2)" "unprognostic (1.19e-1)" "unprognostic (3.45e-2)" "unprognostic (2.85e-2)" "unprognostic (1.43e-1)" "unprognostic (1.38e-1)" "unprognostic (1.68e-1)" "unprognostic (5.73e-2)" "unprognostic (2.51e-2)" "unprognostic (1.07e-2)" "unprognostic (1.53e-2)" "unprognostic (3.80e-1)" C1QBP "gC1Q-R, gC1qR, HABP1, p32, SF2p32" ENSG00000108561 "Complement C1q binding protein" Q07021 17 5432777-5448830 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Adaptive immunity, Apoptosis, Complement pathway, DNA damage, Host-virus interaction, Immunity, Innate immunity, mRNA processing, mRNA splicing, Ribosome biogenesis, Transcription, Transcription regulation" "Cancer-related genes, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 790.0;Esophageal suprabasal cells: 627.3;Extravillous trophoblasts: 453.8;Gastric progenitor cells: 552.4;Migrating cytotrophoblasts: 544.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026483 Supported Supported "Plasma membrane,Mitochondria" "Secreted to blood" "Complement pathway" NA NA 1500000 "Cluster 13: Non-specific - Mitochondria" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 42: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 179 "Plasma membrane" Mitochondria "HPA026483: " "unprognostic (1.74e-2)" "unprognostic (3.81e-2)" "unprognostic (2.67e-2)" "unprognostic (3.18e-1)" "unprognostic (8.18e-2)" "unprognostic (2.70e-2)" "unprognostic (1.31e-1)" "unprognostic (3.13e-1)" "unprognostic (4.46e-2)" "potential prognostic unfavorable (1.15e-4)" "unprognostic (5.19e-3)" "unprognostic (2.39e-1)" "unprognostic (3.65e-1)" "unprognostic (2.86e-3)" "unprognostic (2.88e-3)" "potential prognostic unfavorable (7.40e-4)" "unprognostic (7.88e-2)" "unprognostic (1.67e-1)" "unprognostic (2.17e-1)" "unprognostic (6.68e-2)" "unprognostic (3.27e-1)" "unprognostic (1.24e-1)" "unprognostic (6.43e-2)" "unprognostic (1.59e-2)" "unprognostic (4.79e-2)" "unprognostic (2.25e-1)" "potential prognostic unfavorable (9.85e-4)" "unprognostic (9.75e-2)" "unprognostic (1.02e-1)" "unprognostic (8.34e-2)" "potential prognostic favorable (2.66e-4)" C1QC C1QG ENSG00000159189 "Complement C1q C chain" P02747 1 22643014-22648110 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 893.4" "Group enriched" "Detected in many" 7 "Hofbauer cells: 2312.4;Kupffer cells: 3477.5;Macrophages: 1290.5" "Cell type enriched" "Detected in some" 63 "central nervous system macrophage: 409.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "intermediate monocyte: 56.5" "Lineage enriched" "Detected in single" 559 "monocytes: 56.5" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Spleen - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001471, CAB009828" Supported "Secreted to blood" "Complement pathway" NA NA 513000000 5900000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 7 "CAB009828: , HPA001471: " "unprognostic (3.82e-2)" "unprognostic (2.59e-1)" "unprognostic (1.09e-1)" "unprognostic (2.24e-1)" "unprognostic (1.92e-2)" "unprognostic (2.44e-2)" "unprognostic (1.97e-2)" "unprognostic (2.16e-1)" "unprognostic (1.37e-1)" "unprognostic (3.55e-1)" "unprognostic (8.78e-3)" "unprognostic (1.24e-1)" "unprognostic (2.16e-1)" "unprognostic (1.04e-1)" "unprognostic (8.68e-2)" "unprognostic (3.74e-1)" "unprognostic (1.44e-2)" "unprognostic (5.15e-2)" "unprognostic (7.04e-2)" "unprognostic (3.01e-2)" "unprognostic (3.21e-1)" "unprognostic (4.47e-2)" "unprognostic (9.15e-2)" "unprognostic (1.22e-1)" "unprognostic (1.07e-1)" "unprognostic (8.39e-2)" "unprognostic (4.43e-2)" "unprognostic (9.32e-2)" "unprognostic (4.86e-3)" "unprognostic (4.85e-2)" "unprognostic (1.59e-1)" C1QL1 "C1QRF, C1QTNF14, CRF, CTRP14" ENSG00000131094 "Complement C1q like 1" O75973 17 44959693-44968303 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 41.9;kidney: 17.1" "Cell type enhanced" "Detected in some" "Mesothelial cells: 38.4;Oligodendrocyte progenitor cells: 185.6;Pancreatic islet cells: 81.7;Podocytes: 74.3;Retinal amacrine cells: 110.5;Retinal horizontal cells: 434.7;Schwann cells: 34.3" "Group enriched" "Detected in many" 4 "committed oligodendrocyte precursor: 67.9;LAMP5-LHX6 and Chandelier: 156.3;oligodendrocyte precursor cell: 199.8" "Cancer enriched" "Detected in many" 5 "Glioblastoma Multiforme (TCGA): 167.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 91.1" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Kidney - Podocytes, Liver - Cholangiocytes, Pancreas - Alpha cells, Pancreas - Beta cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071349 Approved Vesicles,Cytosol "Secreted in brain" "Complement pathway" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 109: Neurons - Neuronal signaling" Vesicles Cytosol "HPA071349: " "unprognostic (6.34e-2)" "unprognostic (1.07e-1)" "unprognostic (1.38e-1)" "unprognostic (6.82e-3)" "unprognostic (2.45e-1)" "unprognostic (1.56e-2)" "potential prognostic favorable (1.17e-5)" "unprognostic (1.24e-1)" "unprognostic (8.44e-2)" "validated prognostic unfavorable (5.75e-4)" "validated prognostic unfavorable (8.66e-4)" "unprognostic (5.21e-3)" "unprognostic (1.61e-2)" "unprognostic (4.32e-2)" "unprognostic (8.28e-2)" "unprognostic (1.63e-3)" "unprognostic (3.52e-1)" "unprognostic (7.64e-3)" "unprognostic (1.17e-1)" "unprognostic (1.40e-1)" "unprognostic (9.60e-2)" "unprognostic (2.15e-2)" "unprognostic (5.59e-2)" "unprognostic (2.40e-2)" "unprognostic (3.85e-2)" C1QL2 "C1QTNF10, CTRP10" ENSG00000144119 "Complement C1q like 2" Q7Z5L3 2 119156243-119158751 "Predicted secreted proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "brain: 26.2" "Group enriched" "Detected in some" 15 "Oligodendrocyte progenitor cells: 51.9;Retinal amacrine cells: 151.0" "Cell type enhanced" "Detected in many" "hippocampal dentate gyrus: 21.9;LAMP5-LHX6 and Chandelier: 18.6;oligodendrocyte precursor cell: 49.9" "Cancer enhanced" "Detected in some" "Lung Adenocarcinoma (TCGA): 2.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "Bone cancer: 1.5" "Breast - T-cells" "Region enhanced" "Detected in many" "hippocampal formation: 22.7" "Low region specificity" "Detected in many" "HPA057934, HPA071349" Uncertain Approved Vesicles,Cytosol "Secreted in brain" "Complement pathway" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 29: Forebrain - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 109: Neurons - Neuronal signaling" Vesicles Cytosol "HPA057934: , HPA071349: " "unprognostic (3.87e-1)" "unprognostic (1.03e-1)" "potential prognostic favorable (9.44e-4)" "unprognostic (1.29e-1)" C1QL3 "C1ql, C1QTNF13, CTRP13, K100" ENSG00000165985 "Complement C1q like 3" Q5VWW1 10 16513734-16521879 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "brain: 26.1;retina: 6.9" "Cell type enhanced" "Detected in some" "Adipocytes: 6.5;Brain excitatory neurons: 13.3;Cardiomyocytes: 16.0;Epicardial cells: 9.1;Myonuclei: 7.5;Retinal ganglion cells: 7.7;Rod photoreceptor cells: 17.3" "Cell type enhanced" "Detected in many" "hippocampal dentate gyrus: 82.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Uterine cancer: 5.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "amygdala: 95.8;cerebral cortex: 76.5;hippocampal formation: 68.7" HPA071349 Approved Vesicles,Cytosol "Secreted in brain" "Complement pathway" NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 35: Neurons - Synaptic function & neurogenesis" 1 Vesicles Cytosol "HPA071349: " "unprognostic (2.10e-2)" "unprognostic (3.96e-1)" "unprognostic (2.14e-1)" "potential prognostic favorable (5.26e-5)" "unprognostic (3.97e-2)" "unprognostic (1.83e-1)" "unprognostic (1.22e-1)" "unprognostic (3.72e-1)" C1QL4 "C1QTNF11, CTRP11" ENSG00000186897 "Complement C1q like 4" Q86Z23 12 49332409-49337188 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 3.9" "Cell type enriched" "Detected in some" 4 "Late spermatids: 176.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 5 "pons: 16.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 19.0" "Adipose visceral - Mesothelial cells, Testis - Late spermatids" "Region enhanced" "Detected in some" "midbrain: 6.2" "Region enhanced" "Detected in many" "pons: 11.2" HPA071349 Approved Vesicles,Cytosol "Secreted in brain" "Complement pathway" NA NA "Cluster 67: Testis - Mixed function" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 3: Rhabdoid - Membrane components" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 33 Vesicles Cytosol "HPA071349: " "unprognostic (1.33e-1)" "unprognostic (3.33e-1)" "unprognostic (1.21e-3)" "unprognostic (3.87e-3)" "unprognostic (3.99e-1)" "unprognostic (6.25e-3)" "unprognostic (6.30e-2)" "unprognostic (9.27e-3)" "unprognostic (1.27e-1)" "unprognostic (3.88e-2)" "unprognostic (9.74e-2)" "unprognostic (4.49e-2)" C1QTNF1 "CTRP1, FLJ90694, GIP, ZSIG37" ENSG00000173918 "C1q and TNF related 1" Q9BXJ1 17 79022814-79049788 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 292.8;heart muscle: 270.6" "Cell type enhanced" "Detected in many" "Breast lactating cells: 114.8;Decidual stromal cells: 54.0;Epicardial cells: 104.6;Hepatic stellate cells: 154.9;Pericytes: 154.7;Syncytiotrophoblasts: 69.4;Vascular smooth muscle cells: 271.5" "Group enriched" "Detected in many" 6 "pericyte: 246.7;vascular associated smooth muscle cell: 120.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Adipocytes (Breast), Pituitary gland - Endothelial cells, Prostate - Fibroblasts, Testis - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB025429, HPA051101" Uncertain Approved Nucleoplasm,Cytosol "Secreted to blood" "Complement pathway" NA NA 314000000 35000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 110: Mural cells - ECM organization" 7 "Nucleoplasm, Cytosol" "CAB025429: , HPA051101: " "unprognostic (5.72e-3)" "unprognostic (3.30e-1)" "unprognostic (4.74e-2)" "unprognostic (1.79e-3)" "unprognostic (3.74e-2)" "potential prognostic unfavorable (5.97e-5)" "unprognostic (4.90e-2)" "unprognostic (7.00e-3)" "unprognostic (7.48e-2)" "unprognostic (2.51e-2)" "potential prognostic unfavorable (2.91e-5)" "unprognostic (3.03e-2)" "unprognostic (2.86e-1)" "unprognostic (2.10e-1)" "unprognostic (1.11e-2)" "unprognostic (7.02e-2)" "unprognostic (1.40e-1)" "unprognostic (1.47e-2)" "unprognostic (4.71e-1)" "unprognostic (5.84e-2)" "unprognostic (1.34e-1)" "unprognostic (1.25e-2)" "unprognostic (1.30e-1)" "unprognostic (5.38e-2)" "unprognostic (3.57e-1)" "unprognostic (2.64e-1)" "unprognostic (3.62e-2)" "unprognostic (1.42e-2)" "unprognostic (1.84e-1)" "unprognostic (3.65e-2)" "unprognostic (8.02e-2)" C1QTNF12 "ADIPOLIN, C1QDC2, CTRP12, FAM132A, MGC105127" ENSG00000184163 "C1q and TNF related 12" Q5T7M4 1 1242446-1246722 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 6.4;kidney: 3.5;skin 1: 6.2" "Group enriched" "Detected in some" 8 "Colonocytes: 123.5;Enterocytes: 210.0" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 10.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "head and neck cancer: 3.5" "Kidney - Proximal tubular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA024107 Uncertain Approved Vesicles "Secreted to blood" "Complement pathway" NA NA 38200000 "Cluster 77: Intestine - Digestion" "Cluster 6: Non-specific - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" Vesicles "HPA024107: " "unprognostic (1.38e-1)" "unprognostic (1.82e-2)" "unprognostic (3.44e-2)" "unprognostic (1.37e-1)" "potential prognostic favorable (8.56e-4)" "unprognostic (1.19e-2)" "unprognostic (1.32e-1)" "unprognostic (3.59e-2)" "unprognostic (1.44e-1)" "unprognostic (4.02e-3)" "unprognostic (3.55e-2)" "unprognostic (2.21e-2)" "unprognostic (7.33e-2)" "unprognostic (1.35e-2)" "unprognostic (1.07e-2)" "unprognostic (1.95e-1)" "unprognostic (3.56e-2)" "unprognostic (9.37e-2)" "unprognostic (2.57e-2)" C1QTNF2 CTRP2 ENSG00000145861 "C1q and TNF related 2" Q9BXJ5 5 160347754-160370641 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 13.2" "Cell type enhanced" "Detected in some" "Fibro-adipogenic progenitors: 15.5;Fibroblasts: 17.7;Hepatic stellate cells: 12.9;Leydig cells: 15.7;Myosatellite cells: 8.5;Pericytes: 14.0;Peritubular myoid cells: 28.5;Sertoli cells: 7.1;Smooth muscle cells: 16.0;Vascular smooth muscle cells: 38.6" "Cell type enhanced" "Detected in many" "pericyte: 19.3;vascular associated smooth muscle cell: 27.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "basophil: 1.2" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.2" "Cancer enhanced" "Detected in some" "Sarcoma: 7.0" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Testis - Sertoli cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061290 Uncertain Approved "Golgi apparatus,Centrosome" "Secreted to blood" "Complement pathway" NA NA 1080000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 108: Fibroblasts - ECM organization" 28 "Golgi apparatus, Centrosome" "HPA061290: " "unprognostic (4.66e-3)" "unprognostic (4.38e-2)" "unprognostic (3.85e-1)" "unprognostic (3.44e-2)" "unprognostic (2.54e-1)" "unprognostic (9.14e-3)" "unprognostic (1.19e-2)" "unprognostic (7.99e-2)" "unprognostic (3.49e-2)" "unprognostic (1.42e-1)" "unprognostic (8.53e-2)" "unprognostic (1.36e-1)" "unprognostic (1.10e-1)" "unprognostic (1.31e-2)" "potential prognostic unfavorable (9.85e-5)" "unprognostic (1.17e-1)" C1QTNF3 "2310005P21Rik, Corcs, Cors, Cors-26, CTRP3" ENSG00000082196 "C1q and TNF related 3" Q9BXJ4 5 34017858-34043213 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 31.2;salivary gland: 49.0" "Cell type enhanced" "Detected in some" "Astrocytes: 10.5;Bergmann glia: 39.6;Brain excitatory neurons: 5.3;Brain inhibitory neurons: 7.4;Choroid plexus epithelial cells: 12.4;Early spermatids: 7.8;Ependymal cells: 10.1;Microglia: 8.1;Oligodendrocyte progenitor cells: 19.8;Oligodendrocytes: 32.0;Other brain neurons: 8.1" "Cell type enhanced" "Detected in all" "Bergmann glia: 57.0" "Cancer enhanced" "Detected in all" "Kidney Renal Papillary Cell Carcinoma (TCGA): 44.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 23.9;skin cancer: 12.0" "Adipose subcutaneous - Adipose progenitor cells, Minor Salivary Gland - Minor salivary glandular cells, Spleen - B-cells (Spleen), Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA064996, HPA066011" Uncertain Approved "Golgi apparatus" "Secreted to blood" "Complement pathway" NA NA 44100000 13000000 "Cluster 42: Retina - Visual perception" "Cluster 25: Non-specific - Transcription" "Cluster 20: Myeloma - Immune response" "Cluster 80: Oligodendrocytes - Myelination" 2 "Golgi apparatus" "HPA064996: , HPA066011: " "unprognostic (2.14e-2)" "unprognostic (7.81e-2)" "unprognostic (5.21e-2)" "unprognostic (2.21e-2)" "unprognostic (8.17e-2)" "unprognostic (4.51e-1)" "unprognostic (8.74e-2)" "unprognostic (5.91e-3)" "unprognostic (1.77e-1)" "potential prognostic unfavorable (6.28e-6)" "potential prognostic favorable (1.38e-6)" "unprognostic (1.82e-2)" "unprognostic (3.74e-2)" "unprognostic (3.31e-2)" "unprognostic (1.52e-1)" "unprognostic (2.86e-2)" "unprognostic (9.61e-2)" "unprognostic (4.09e-2)" "unprognostic (2.42e-2)" "unprognostic (2.11e-3)" "potential prognostic unfavorable (7.62e-4)" "unprognostic (7.59e-2)" "unprognostic (3.36e-1)" "unprognostic (6.19e-2)" "unprognostic (2.19e-1)" "unprognostic (8.78e-3)" "unprognostic (2.58e-2)" "unprognostic (2.95e-3)" "unprognostic (3.06e-2)" "unprognostic (9.42e-3)" "unprognostic (1.18e-1)" C1QTNF4 "CTRP4, ZACRP4" ENSG00000172247 "C1q and TNF related 4" Q9BXJ3 11 47589667-47594411 "Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 129.5" "Cell type enhanced" "Detected in some" "Astrocytes: 48.0;Bergmann glia: 20.3;Brain excitatory neurons: 27.5;Brain inhibitory neurons: 47.0;Ependymal cells: 7.2;Oligodendrocyte progenitor cells: 7.4;Oligodendrocytes: 9.9;Other brain neurons: 31.4" "Cell type enhanced" "Detected in all" "cerebellar inhibitory: 172.5" "Group enriched" "Detected in some" 4 "Glioblastoma Multiforme (TCGA): 1.9;Ovary Serous Cystadenocarcinoma (TCGA): 2.1;Testicular Germ Cell Tumor (TCGA): 3.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Leukemia: 2.5" "Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041032 Approved Uncertain "Golgi apparatus,Vesicles" "Secreted in brain" Cytokine NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 98: Neurons - Neurotransmission & signaling" 3 "Golgi apparatus, Vesicles" "HPA041032: " "unprognostic (1.33e-1)" "potential prognostic unfavorable (8.48e-4)" "unprognostic (2.81e-1)" "unprognostic (5.02e-2)" C1QTNF5 "CTRP5, DKFZp586B0621, LORD" ENSG00000223953 "C1q and TNF related 5" Q9BXJ0 11 119338942-119340940 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "choroid plexus: 554.7" "Cell type enriched" "Detected in some" 7 "Choroid plexus epithelial cells: 235.2" "Cell type enriched" "Detected in many" 8 "choroid plexus epithelial cell: 372.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 6.7;Sarcoma: 4.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025607, HPA038604" Uncertain "Secreted to blood" "Complement pathway" NA NA 219000000 580000 "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 5 "CAB025607: , HPA038604: " "unprognostic (9.75e-3)" "unprognostic (1.35e-1)" "unprognostic (7.76e-2)" "potential prognostic unfavorable (7.56e-4)" "unprognostic (1.52e-1)" "unprognostic (3.03e-1)" "unprognostic (9.31e-2)" "unprognostic (1.82e-1)" "unprognostic (3.40e-3)" "unprognostic (1.08e-3)" "unprognostic (7.98e-2)" "unprognostic (3.29e-1)" "unprognostic (1.68e-1)" "unprognostic (2.77e-1)" "unprognostic (5.15e-3)" "unprognostic (2.43e-2)" "unprognostic (1.16e-1)" "unprognostic (1.37e-2)" "potential prognostic unfavorable (7.46e-4)" "unprognostic (6.18e-2)" "unprognostic (3.68e-2)" "unprognostic (3.59e-2)" "unprognostic (1.97e-2)" "unprognostic (9.86e-3)" "potential prognostic unfavorable (8.94e-5)" "unprognostic (3.54e-3)" "unprognostic (1.21e-1)" "unprognostic (1.07e-1)" "unprognostic (2.19e-1)" C1QTNF6 "CTRP6, ZACRP6" ENSG00000133466 "C1q and TNF related 6" Q9BXI9 22 37180166-37199385 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 29.8;placenta: 27.9" "Cell type enriched" "Detected in many" 10 "Extravillous trophoblasts: 598.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002042 Enhanced Approved Nucleoplasm "Secreted to blood" "Complement pathway" No No 354000000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 75: Ovary - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 3 Nucleoplasm "HPA002042: " "unprognostic (1.22e-1)" "unprognostic (8.88e-2)" "unprognostic (6.85e-2)" "potential prognostic unfavorable (1.73e-4)" "unprognostic (7.42e-2)" "unprognostic (9.07e-2)" "unprognostic (7.82e-3)" "unprognostic (2.93e-2)" "unprognostic (3.01e-2)" "unprognostic (8.33e-2)" "potential prognostic unfavorable (4.16e-8)" "unprognostic (1.45e-2)" "unprognostic (5.95e-2)" "unprognostic (1.37e-2)" "unprognostic (1.46e-1)" "potential prognostic unfavorable (2.55e-9)" "unprognostic (2.23e-3)" "unprognostic (1.43e-1)" "unprognostic (3.89e-2)" "unprognostic (6.92e-2)" "unprognostic (6.21e-2)" "unprognostic (7.33e-2)" "potential prognostic unfavorable (2.92e-4)" "unprognostic (7.85e-2)" "unprognostic (1.43e-1)" "unprognostic (6.87e-2)" "unprognostic (6.67e-3)" "unprognostic (8.24e-3)" "unprognostic (9.72e-2)" "unprognostic (6.66e-3)" "unprognostic (5.88e-3)" C1QTNF7 CTRP7 ENSG00000163145 "C1q and TNF related 7" Q9BXJ2 4 15339818-15446167 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 268.7;Epicardial cells: 50.0;Fibro-adipogenic progenitors: 103.7;Fibroblasts: 67.3;Leydig cells: 46.9;Ovarian stromal cells: 41.8;Peritubular myoid cells: 60.5;Retinal bipolar cells: 151.3;Vascular smooth muscle cells: 68.2" "Cell type enhanced" "Detected in all" "fibroblast: 55.0;pericyte: 53.1;vascular associated smooth muscle cell: 92.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adrenal gland - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Minor Salivary Gland - Fibroblasts, Pancreas - Fibroblasts, Pituitary gland - Fibroblasts, Prostate - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB007055, HPA051797, HPA055392" Uncertain Approved Vesicles "Secreted to blood" "Complement pathway" NA NA 238000000 "Cluster 75: Ovary - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 89: Adipocytes - Lipid metabolism" Vesicles "CAB007055: , HPA051797: , HPA055392: " "unprognostic (2.44e-3)" "unprognostic (5.93e-2)" "unprognostic (2.78e-1)" "unprognostic (1.14e-1)" "potential prognostic favorable (5.98e-4)" "unprognostic (3.50e-3)" "unprognostic (3.33e-1)" "unprognostic (1.35e-1)" "unprognostic (8.80e-2)" "unprognostic (9.02e-3)" "unprognostic (1.86e-1)" "unprognostic (7.15e-3)" "unprognostic (1.68e-1)" "unprognostic (6.68e-2)" "unprognostic (2.00e-2)" "unprognostic (2.30e-1)" "unprognostic (2.39e-1)" C1QTNF8 "CTRP8, UNQ5829" ENSG00000184471 "C1q and TNF related 8" P60827 16 1088226-1096244 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "blood vessel: 2.4;fallopian tube: 1.7;pituitary gland: 1.6" "Cell type enhanced" "Detected in some" "Astrocytes: 2.2;Cardiomyocytes: 4.7;Endometrial ciliated cells: 18.0;Ependymal cells: 13.7;Epicardial cells: 2.3;Epididymal efferent duct ciliated cells: 10.5;Fallopian tube ciliated cells: 5.0;Leydig cells: 3.2;Respiratory ciliated cells: 2.8" "Group enriched" "Detected in some" 5 "astrocyte: 4.8;ependymal cell: 15.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells" "Not detected" "Not detected" HPA056438 Uncertain "Secreted - unknown location" "Complement pathway" NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 46: Brainstem - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 34: Ciliated cells - Cilia assembly & function" "HPA056438: " C1QTNF9 "AQL1, C1QTNF9A, CTRP9, MGC48915" ENSG00000240654 "C1q and TNF related 9" P0C862 13 24307166-24322535 "Predicted secreted proteins, Transporters" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skeletal muscle: 7.9" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 1.2;Early spermatids: 2.3;Late primary spermatocytes: 1.4;Late spermatids: 1.3;pDCs: 1.3;Undifferentiated spermatogonia: 2.0;Vascular endothelial cells: 5.3" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 2.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA056632 Uncertain "Secreted to blood" "Complement pathway" NA NA 210000000 45000 "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 29: Forebrain - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 6 "HPA056632: " "unprognostic (1.98e-2)" "unprognostic (4.23e-1)" "unprognostic (3.60e-2)" C1QTNF9B CTRP9B ENSG00000205863 "C1q and TNF related 9B" B2RNN3 13 23891099-23897502 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.5;skin 1: 16.9;testis: 8.3" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 2.4;Cardiomyocytes: 3.3;Early spermatids: 1.9;Late spermatids: 3.2;Undifferentiated spermatogonia: 3.6" "Cell type enhanced" "Detected in some" "hippocampal dentate gyrus: 12.9" "Cancer enriched" "Detected in many" 12 "Prostate Adenocarcinoma (TCGA): 37.5" "Region enriched" "Detected in many" 4 "hippocampal formation: 17.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells" HPA056632 Uncertain "Secreted - unknown location" "Complement pathway" NA NA "Cluster 47: Testis - Mixed function" "Cluster 29: Forebrain - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" 19 "HPA056632: " "unprognostic (6.35e-2)" "unprognostic (1.92e-1)" "unprognostic (1.91e-2)" "unprognostic (1.95e-3)" "unprognostic (1.21e-2)" "unprognostic (6.35e-2)" "unprognostic (1.50e-1)" "unprognostic (7.28e-2)" "unprognostic (3.93e-1)" "potential prognostic favorable (3.66e-4)" "unprognostic (4.57e-2)" "unprognostic (4.42e-3)" "potential prognostic unfavorable (6.35e-4)" "potential prognostic favorable (4.82e-4)" "unprognostic (1.46e-1)" "unprognostic (2.45e-3)" "unprognostic (7.21e-2)" "unprognostic (3.32e-2)" "unprognostic (6.73e-2)" "unprognostic (1.22e-2)" "unprognostic (3.50e-2)" "unprognostic (2.85e-1)" "unprognostic (3.58e-2)" "unprognostic (7.82e-2)" "unprognostic (3.36e-2)" "unprognostic (1.28e-1)" C1R ENSG00000159403 "Complement C1r" 12 7080214-7092540 "Human disease related genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "liver: 1733.3" "Cell type enhanced" "Detected in some" "Astrocytes: 9.6;Decidual stromal cells: 8.9;Endometrial stromal cells: 13.5;Epicardial cells: 45.5;Fibroblasts: 37.5;Mesothelial cells: 22.5;Pericytes: 12.9;Podocytes: 35.1" "Cell type enriched" "Detected in many" 5 "fibroblast: 154.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 73.9" "Adipose visceral - Adipose progenitor cells, Liver - Hepatocytes, Lung - Fibroblasts_2, Spleen - Fibroblasts_1, Thyroid gland - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001251, HPA001551" Uncertain Uncertain Nucleoplasm,Cytosol NA NA "Cluster 11: T-cells - Unknown function" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 39: Astrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 1 "Nucleoplasm, Cytosol" "HPA001251: , HPA001551: " "unprognostic (1.09e-2)" "unprognostic (9.04e-3)" "unprognostic (1.48e-1)" "unprognostic (1.03e-2)" "unprognostic (5.40e-2)" "unprognostic (6.09e-2)" "unprognostic (2.18e-2)" "unprognostic (2.70e-3)" "unprognostic (1.22e-1)" "unprognostic (4.48e-2)" "potential prognostic unfavorable (3.06e-7)" "unprognostic (8.13e-3)" "unprognostic (1.10e-2)" "unprognostic (8.07e-2)" "potential prognostic favorable (5.25e-5)" "unprognostic (1.01e-1)" "unprognostic (1.16e-2)" "unprognostic (6.40e-2)" "unprognostic (5.89e-3)" "unprognostic (2.35e-2)" "unprognostic (2.31e-1)" "unprognostic (6.44e-2)" "unprognostic (1.71e-2)" "unprognostic (3.58e-2)" "unprognostic (7.88e-2)" "unprognostic (5.31e-3)" "unprognostic (1.03e-1)" "unprognostic (3.01e-3)" "unprognostic (4.56e-2)" "unprognostic (4.34e-2)" "unprognostic (2.07e-1)" C1RL "C1r-LP, C1RL1" ENSG00000139178 "Complement C1r subcomponent like" Q9NZP8 12 7089587-7109238 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 134.2" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 29.8;Distal convoluted tubule cells: 33.9;Loop of henle epithelial cells: 39.5;Microglia: 29.0;Papillary tip epithelial cells: 45.4;Podocytes: 34.6;Proximal tubule cells: 47.4;Renal collecting duct intercalated cells: 23.0;Renal collecting duct principal cells: 41.7;Renal connecting tubule cells: 32.8" "Cell type enhanced" "Detected in many" "fibroblast: 82.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 5.4" "Lineage enriched" "Detected in many" 4 "granulocytes: 5.4" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA011338, CAB026172" Supported "Secreted to blood" "Complement pathway" NA NA 5500000000 3600000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 39: Astrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 105: Non-specific - Mixed function" 2 "CAB026172: , HPA011338: " "unprognostic (7.56e-3)" "unprognostic (4.11e-2)" "unprognostic (2.54e-3)" "potential prognostic unfavorable (1.90e-4)" "unprognostic (1.19e-1)" "unprognostic (1.13e-1)" "validated prognostic unfavorable (7.48e-4)" "validated prognostic unfavorable (7.27e-5)" "unprognostic (5.73e-2)" "unprognostic (7.21e-2)" "potential prognostic unfavorable (1.00e-5)" "unprognostic (7.01e-3)" "unprognostic (8.93e-2)" "unprognostic (2.22e-2)" "potential prognostic favorable (9.60e-4)" "unprognostic (2.20e-2)" "potential prognostic unfavorable (1.37e-4)" "unprognostic (2.02e-1)" "unprognostic (4.97e-2)" "unprognostic (1.73e-1)" "unprognostic (5.38e-2)" "potential prognostic unfavorable (3.53e-4)" "unprognostic (9.27e-3)" "unprognostic (6.83e-2)" "unprognostic (1.32e-1)" "unprognostic (8.33e-3)" "unprognostic (1.25e-1)" "unprognostic (2.52e-3)" "unprognostic (2.60e-2)" "unprognostic (1.24e-1)" "unprognostic (2.67e-2)" C1S ENSG00000182326 "Complement C1s" P09871 12 6988259-7071032 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease variant, Ehlers-Danlos syndrome, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "liver: 2663.1" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 1563.7;Fibroblasts: 960.8;Hepatic stellate cells: 580.9;Hepatocytes: 3326.7;Leydig cells: 1065.9;Ovarian stromal cells: 427.5;Peritubular myoid cells: 642.6" "Cell type enriched" "Detected in all" 5 "fibroblast: 348.0" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 745.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Liver - Hepatocytes, Lung - Fibroblasts_2, Prostate - Fibroblasts, Spleen - Fibroblasts_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB016722, HPA018852" Supported Approved Nucleoplasm,Cytosol "Secreted to blood" "Complement pathway" NA NA 93000000000 27000000000 "Cluster 53: Liver - Plasma proteins" "Cluster 39: Astrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 4 Nucleoplasm Cytosol "CAB016722: , HPA018852: " "unprognostic (7.81e-3)" "unprognostic (6.27e-3)" "unprognostic (1.58e-1)" "unprognostic (6.27e-2)" "unprognostic (5.88e-2)" "unprognostic (1.86e-2)" "unprognostic (1.59e-2)" "unprognostic (2.55e-3)" "unprognostic (1.04e-1)" "unprognostic (9.25e-2)" "potential prognostic unfavorable (1.67e-5)" "unprognostic (1.49e-3)" "potential prognostic unfavorable (7.14e-5)" "validated prognostic favorable (5.46e-4)" "validated prognostic favorable (2.13e-5)" "unprognostic (1.20e-1)" "unprognostic (7.56e-2)" "unprognostic (9.06e-2)" "unprognostic (2.49e-2)" "unprognostic (1.31e-2)" "unprognostic (7.88e-2)" "unprognostic (1.39e-1)" "unprognostic (1.23e-1)" "unprognostic (4.93e-2)" "unprognostic (6.79e-2)" "unprognostic (7.09e-3)" "unprognostic (2.72e-1)" "unprognostic (5.77e-2)" "unprognostic (1.74e-3)" "unprognostic (1.27e-2)" "unprognostic (1.65e-3)" C2 ENSG00000166278 "Complement C2" P06681 6 31897785-31945673 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 454.7" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 11.6;Brain excitatory neurons: 9.4;Brain inhibitory neurons: 11.5;Choroid plexus epithelial cells: 9.6;Decidual stromal cells: 8.9;Distal convoluted tubule cells: 10.1;Hepatocytes: 8.1;Hofbauer cells: 16.3;Loop of henle epithelial cells: 8.5;Other brain neurons: 8.5;Podocytes: 11.6;Proximal tubule cells: 11.3;Renal collecting duct intercalated cells: 6.8;Renal collecting duct principal cells: 8.3;Renal connecting tubule cells: 10.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 250.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 20.7;non-classical monocyte: 26.1" "Lineage enriched" "Detected in single" 33 "monocytes: 26.1" "Group enriched" "Detected in many" 4 "liver cancer: 11.4;Myeloma: 14.9;thyroid cancer: 5.1" "Adipose subcutaneous - Macrophages, Adrenal gland - Macrophages, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Fibroblasts_2, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" CAB016775 Supported "Secreted to blood" "Complement pathway" NA NA 37800000000 14000000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 102: Non-specific - Mixed function" 7 "CAB016775: " "unprognostic (8.96e-2)" "unprognostic (1.11e-1)" "unprognostic (9.42e-3)" "unprognostic (1.03e-1)" "unprognostic (2.04e-1)" "unprognostic (1.32e-1)" "unprognostic (3.36e-3)" "unprognostic (2.02e-3)" "unprognostic (7.84e-2)" "unprognostic (4.05e-1)" "unprognostic (1.44e-1)" "unprognostic (5.22e-2)" "unprognostic (1.83e-1)" "unprognostic (2.99e-2)" "unprognostic (9.84e-2)" "unprognostic (2.71e-2)" "unprognostic (5.88e-2)" "unprognostic (5.09e-3)" "unprognostic (1.59e-1)" "unprognostic (3.14e-1)" "unprognostic (1.71e-1)" "unprognostic (1.47e-1)" "unprognostic (5.33e-2)" "unprognostic (8.48e-2)" "unprognostic (1.74e-2)" "unprognostic (1.02e-1)" "unprognostic (1.82e-1)" "unprognostic (1.69e-1)" "unprognostic (1.84e-2)" "unprognostic (1.05e-1)" "unprognostic (5.18e-2)" C20orf141 dJ860F19.4 ENSG00000258713 "Chromosome 20 open reading frame 141" Q9NUB4 20 2814987-2815833 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 81 "testis: 124.1" "Cell type enriched" "Detected in some" 4 "Late spermatids: 4880.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" HPA077873 Approved "Vesicles,Plasma membrane" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 4 "Plasma membrane" Vesicles "HPA077873: " "unprognostic (4.56e-2)" C20orf144 "bclt, dJ63M2.6" ENSG00000149609 "Chromosome 20 open reading frame 144" Q9BQM9 20 33662327-33665619 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1184 "testis: 175.0" "Group enriched" "Detected in some" 4 "Early spermatids: 2586.7;Late spermatids: 3595.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA019029 Enhanced NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" "HPA019029: " "unprognostic (2.57e-1)" C20orf173 dJ477O4.4 ENSG00000125975 "Chromosome 20 open reading frame 173" Q96LM9 20 35523186-35529652 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 170 "testis: 33.6" "Group enriched" "Detected in some" 8 "Early spermatids: 503.9;Late spermatids: 148.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA076859 Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 37: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 1 Nucleoplasm "Vesicles, Plasma membrane" "HPA076859: " C20orf202 ENSG00000215595 "Chromosome 20 open reading frame 202" A1L168 20 1203454-1209076 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 2.5" "Cell type enhanced" "Detected in some" "Breast lactating cells: 2.4;Early spermatids: 6.1;Enterocytes: 1.7;Innate lymphoid cells: 1.2;Late spermatids: 3.3;Ocular epithelial cells: 3.1;Pericytes: 2.7;Pituicytes/FSCs: 1.2;Salivary duct cells: 1.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 15 "cerebellum: 8.0;olfactory bulb: 2.6" "Low region specificity" "Detected in many" NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 110: Mural cells - ECM organization" 7 "unprognostic (2.30e-1)" "unprognostic (2.96e-2)" "unprognostic (1.20e-3)" "unprognostic (1.13e-3)" C20orf203 FLJ33706 ENSG00000198547 "Chromosome 20 open reading frame 203" Q8NBC4 20 32631625-32673941 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 1.7" "Cell type enhanced" "Detected in some" "Brain inhibitory neurons: 1.1;Retinal horizontal cells: 2.0" "Low cell type specificity" "Detected in some" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "basophil: 1.0" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.0" "Not detected" "Not detected" NA NA "Cluster 65: Brain - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 109: Neurons - Neuronal signaling" C20orf204 "DKFZp434G015, FLJ27267, LINC00176, NCRNA00176, PRR17" ENSG00000196421 "Chromosome 20 open reading frame 204" A0A1B0GTL2 20 64034344-64039962 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "brain: 10.6" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 5.3;Innate lymphoid cells: 19.0;Lymphatic endothelial cells: 8.6;Medullary thymic epithelial cells: 4.8;Thyrotrophs: 6.7;Tuft cells: 11.5;Vascular endothelial cells: 5.6" "Cell type enhanced" "Detected in many" "upper rhombic lip: 12.7" "Cancer enriched" "Detected in many" 5 "Ovary Serous Cystadenocarcinoma (TCGA): 32.9" "Region enriched" "Detected in some" 8 "cerebellum: 8.3" "Group enriched" "Detected in some" 4 "memory CD4 T-cell: 2.6;naive CD4 T-cell: 5.9;naive CD8 T-cell: 4.8;T-reg: 1.5" "Lineage enriched" "Detected in single" 9 "T-cells: 5.9" "Cancer enhanced" "Detected in some" "liver cancer: 4.0;lymphoma: 2.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 71: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 18: Liver cancer - Metabolism" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" "unprognostic (2.85e-1)" "unprognostic (1.06e-1)" "unprognostic (4.53e-3)" "potential prognostic favorable (7.00e-4)" "unprognostic (7.80e-2)" "unprognostic (5.74e-2)" "unprognostic (1.92e-2)" "unprognostic (2.23e-1)" "unprognostic (4.32e-2)" "unprognostic (1.86e-1)" "unprognostic (8.15e-2)" "unprognostic (2.21e-2)" C20orf27 FLJ20550 ENSG00000101220 "Chromosome 20 open reading frame 27" Q9GZN8 20 3753508-3767781 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 318.6" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 786.3;Endometrial stromal cells: 124.7;Hofbauer cells: 205.3;Monocyte progenitors: 151.0;Ovarian stromal cells: 128.5;Smooth muscle cells: 145.0" "Cell type enhanced" "Detected in all" "pericyte: 110.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 144.8;intermediate monocyte: 249.3;myeloid DC: 199.7;non-classical monocyte: 236.3" "Group enriched" "Detected in all" 5 "dendritic cells: 199.7;monocytes: 249.3" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Fibroblasts, Prostate - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047483 Approved Approved Nucleoplasm,Cytosol "Secreted in other tissues" "No annotated function" NA NA 78000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 94: Gonadal somatic cells - Mixed function" 6 "Nucleoplasm, Cytosol" "HPA047483: " "unprognostic (1.25e-1)" "unprognostic (9.91e-2)" "unprognostic (5.46e-2)" "unprognostic (6.92e-2)" "unprognostic (5.12e-2)" "unprognostic (5.43e-2)" "unprognostic (2.72e-1)" "unprognostic (2.54e-1)" "unprognostic (1.03e-1)" "unprognostic (4.57e-2)" "unprognostic (8.84e-2)" "unprognostic (2.63e-1)" "unprognostic (1.51e-2)" "validated prognostic unfavorable (2.03e-6)" "validated prognostic unfavorable (3.54e-7)" "unprognostic (1.42e-1)" "unprognostic (1.32e-2)" "unprognostic (1.60e-1)" "unprognostic (6.27e-2)" "unprognostic (1.82e-1)" "unprognostic (6.32e-2)" "unprognostic (8.16e-3)" "unprognostic (3.72e-2)" "unprognostic (1.30e-1)" "unprognostic (5.05e-2)" "unprognostic (1.01e-2)" "unprognostic (2.23e-1)" "unprognostic (6.74e-2)" "unprognostic (3.10e-1)" "unprognostic (2.73e-2)" "unprognostic (1.03e-1)" C20orf85 "bA196N14.1, LLC1" ENSG00000124237 "Chromosome 20 open reading frame 85" Q9H1P6 20 58150902-58161150 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "fallopian tube: 427.9" "Cell type enhanced" "Detected in some" "Early spermatids: 386.3;Endometrial ciliated cells: 1062.6;Epididymal efferent duct ciliated cells: 1097.9;Fallopian tube ciliated cells: 2555.3;Late primary spermatocytes: 369.1;Late spermatids: 589.3;Respiratory ciliated cells: 2028.9" "Cell type enriched" "Detected in some" 4 "ependymal cell: 27.4" "Cancer enriched" "Detected in many" 4 "Uterine Corpus Endometrial Carcinoma (TCGA): 79.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in single" 5 "basal ganglia: 1.6" "Region enhanced" "Detected in many" "midbrain: 26.6" "HPA058271, HPA065540" Enhanced Approved "Mid piece" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" 19 "Mid piece" "HPA058271: , HPA065540: " "unprognostic (9.01e-3)" "unprognostic (1.20e-1)" "unprognostic (5.76e-2)" "unprognostic (9.97e-2)" "unprognostic (2.04e-1)" "unprognostic (1.60e-1)" "unprognostic (1.08e-1)" "unprognostic (1.05e-2)" "unprognostic (2.50e-2)" "unprognostic (2.48e-1)" "unprognostic (3.13e-1)" "unprognostic (7.15e-2)" "unprognostic (3.94e-2)" C20orf96 dJ1103G7.2 ENSG00000196476 "Chromosome 20 open reading frame 96" Q9NUD7 20 270863-290778 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 102.4;Endometrial ciliated cells: 102.2;Ependymal cells: 110.6;Epididymal efferent duct ciliated cells: 122.6;Fallopian tube ciliated cells: 226.7;Late primary spermatocytes: 153.5;Respiratory ciliated cells: 198.7" "Cell type enhanced" "Detected in all" "ependymal cell: 129.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048649, HPA056227" Approved Approved "Centriolar satellite" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 21: Testis - Mixed function" "Cluster 3: Choroid plexus - Cilium" "Cluster 62: Non-specific - Plasma proteins" "Cluster 107: Ciliated cells - Cilia assembly & function" 7 "Centriolar satellite" "HPA048649: , HPA056227: " "unprognostic (5.74e-3)" "unprognostic (5.42e-2)" "unprognostic (1.62e-1)" "unprognostic (6.92e-2)" "unprognostic (6.15e-2)" "unprognostic (6.64e-2)" "unprognostic (1.18e-2)" "unprognostic (1.10e-2)" "unprognostic (1.16e-1)" "unprognostic (2.68e-2)" "unprognostic (3.89e-2)" "unprognostic (2.44e-2)" "potential prognostic favorable (5.87e-6)" "potential prognostic unfavorable (8.85e-6)" "unprognostic (3.31e-2)" "unprognostic (2.24e-2)" "unprognostic (2.64e-1)" "unprognostic (4.19e-2)" "unprognostic (1.73e-2)" "unprognostic (3.31e-1)" "unprognostic (3.74e-3)" "potential prognostic favorable (1.54e-4)" "unprognostic (5.04e-3)" "unprognostic (2.78e-3)" "unprognostic (1.81e-2)" "unprognostic (1.58e-1)" "unprognostic (3.31e-1)" "unprognostic (2.69e-1)" "unprognostic (1.83e-1)" "unprognostic (4.81e-2)" "unprognostic (2.53e-1)" C21orf140 FAM243A ENSG00000222018 "Chromosome 21 open reading frame 140" B9A014 21 34400112-34401072 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" HPA045123 Uncertain NA NA "Cluster 47: Testis - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 56: Non-specific - Sensory perception" "HPA045123: " "unprognostic (1.60e-2)" "unprognostic (7.46e-2)" "unprognostic (2.57e-1)" C21orf58 ENSG00000160298 "Chromosome 21 open reading frame 58" P58505 21 46300181-46323875 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 24.9;pituitary gland: 20.6" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 104.3;Endometrial ciliated cells: 157.9;Ependymal cells: 74.7;Epididymal efferent duct ciliated cells: 139.8;Erythrocyte progenitors: 115.2;Fallopian tube ciliated cells: 192.4;Platelets: 91.9;Respiratory ciliated cells: 231.0" "Cell type enriched" "Detected in all" 4 "ependymal cell: 75.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "basophil: 4.4" "Lineage enriched" "Detected in many" 4 "granulocytes: 4.4" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Not detected" "Not detected" "HPA035110, HPA035111" Uncertain Approved "Nucleoplasm,Nuclear bodies,Primary cilium transition zone" NA Yes "Cluster 46: Basophils - Proteolysis" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 46: Brainstem - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 107: Ciliated cells - Cilia assembly & function" Nucleoplasm "Nuclear bodies, Primary cilium transition zone" "HPA035110: , HPA035111: " "unprognostic (1.34e-1)" "unprognostic (2.04e-1)" "unprognostic (6.34e-2)" "unprognostic (2.17e-1)" "unprognostic (1.01e-2)" "unprognostic (4.48e-1)" "unprognostic (2.79e-2)" "unprognostic (3.45e-1)" "unprognostic (1.10e-3)" "unprognostic (1.02e-2)" "validated prognostic unfavorable (1.15e-6)" "validated prognostic unfavorable (4.32e-4)" "unprognostic (2.94e-1)" "unprognostic (5.54e-3)" "unprognostic (2.22e-3)" "unprognostic (1.34e-1)" "unprognostic (3.48e-2)" "unprognostic (1.63e-1)" "unprognostic (1.53e-2)" "unprognostic (2.24e-1)" "unprognostic (2.19e-2)" "unprognostic (2.21e-3)" "unprognostic (2.85e-1)" "unprognostic (1.36e-1)" "unprognostic (1.25e-1)" "unprognostic (1.21e-1)" "unprognostic (7.43e-2)" "unprognostic (1.94e-1)" "unprognostic (5.72e-2)" "unprognostic (1.82e-1)" "unprognostic (9.22e-2)" C21orf62 "B37, C21orf120, PRED81" ENSG00000205929 "Chromosome 21 open reading frame 62" Q9NYP8 21 32790673-32813743 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "choroid plexus: 22.0;epididymis: 7.9;ovary: 8.4" "Group enriched" "Detected in some" 5 "Choroid plexus epithelial cells: 118.9;Ependymal cells: 37.6;Loop of henle epithelial cells: 37.4" "Group enriched" "Detected in many" 4 "choroid plexus epithelial cell: 104.6;ependymal cell: 38.0" "Group enriched" "Detected in some" 6 "Glioblastoma Multiforme (TCGA): 24.2;Kidney Renal Papillary Cell Carcinoma (TCGA): 8.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016899 Enhanced "Secreted - unknown location" "No annotated function" NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 3: Choroid plexus - Cilium" "Cluster 72: Neuronal - Signal transduction" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 1 "HPA016899: " "unprognostic (3.53e-1)" "unprognostic (2.82e-1)" "potential prognostic unfavorable (7.71e-6)" "unprognostic (2.17e-3)" "unprognostic (4.40e-2)" "unprognostic (1.20e-1)" "unprognostic (2.29e-1)" "unprognostic (1.38e-2)" "unprognostic (2.03e-1)" "unprognostic (2.33e-1)" "unprognostic (1.63e-2)" C21orf91 "C21orf14, C21orf38, CSSG1, EURL, YG81" ENSG00000154642 "Chromosome 21 open reading frame 91" Q9NYK6 21 17788974-17819386 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Early spermatids: 491.5" "Cell type enhanced" "Detected in many" "oligodendrocyte: 165.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 111.2" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018288, HPA049030" Approved Approved "Microtubules,Cytokinetic bridge" Yes NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 1 Microtubules "Cytokinetic bridge" "HPA018288: , HPA049030: " "unprognostic (1.66e-1)" "unprognostic (2.10e-1)" "unprognostic (2.90e-2)" "unprognostic (4.90e-2)" "unprognostic (1.51e-1)" "unprognostic (8.89e-2)" "unprognostic (7.49e-2)" "unprognostic (2.17e-1)" "unprognostic (8.97e-3)" "unprognostic (4.62e-2)" "potential prognostic favorable (6.21e-5)" "unprognostic (1.89e-2)" "unprognostic (2.18e-1)" "unprognostic (3.17e-1)" "unprognostic (3.19e-1)" "unprognostic (1.49e-1)" "unprognostic (1.36e-2)" "unprognostic (2.25e-2)" "unprognostic (2.39e-2)" "unprognostic (1.74e-1)" "unprognostic (1.91e-1)" "unprognostic (7.67e-2)" "unprognostic (1.11e-2)" "unprognostic (3.47e-2)" "unprognostic (4.33e-2)" "unprognostic (9.55e-2)" "unprognostic (2.85e-1)" "unprognostic (9.28e-2)" "unprognostic (1.59e-1)" "unprognostic (8.44e-2)" "unprognostic (1.47e-1)" C22orf15 "FLJ36561, N27C7-3" ENSG00000169314 "Chromosome 22 open reading frame 15" Q8WYQ4 22 23762990-23765863 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "fallopian tube: 17.2" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 22.6;Ependymal cells: 35.7;Epididymal efferent duct ciliated cells: 30.2;Fallopian tube ciliated cells: 90.4;Late primary spermatocytes: 16.0;Respiratory ciliated cells: 114.2" "Cell type enriched" "Detected in single" 68 "ependymal cell: 42.5" "Cancer enhanced" "Detected in single" "Uterine Corpus Endometrial Carcinoma (TCGA): 2.2" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.0" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in single" "Bone cancer: 1.1" "Lung - Respiratory ciliated cells, Prostate - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA019494 Approved "Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 107: Ciliated cells - Cilia assembly & function" 2 "Endoplasmic reticulum, Plasma membrane" "HPA019494: " "unprognostic (5.00e-2)" "unprognostic (1.78e-1)" "unprognostic (2.44e-1)" C22orf23 "EVG1, FLJ32787, LOC84645" ENSG00000128346 "Chromosome 22 open reading frame 23" Q9BZE7 22 37943050-37953669 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "skin 1: 24.5;testis: 87.9" "Group enriched" "Detected in many" 6 "Early spermatids: 243.1;Late primary spermatocytes: 615.2;Late spermatids: 480.5" "Cell type enhanced" "Detected in many" "ependymal cell: 22.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Prostate - Smooth muscle cells, Stomach - Parietal cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000650 Approved Nucleoplasm NA NA "Cluster 47: Testis - Mixed function" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 6 Nucleoplasm "HPA000650: " "unprognostic (2.66e-2)" "unprognostic (1.01e-2)" "unprognostic (1.28e-1)" "unprognostic (1.02e-1)" "unprognostic (1.24e-1)" "unprognostic (3.81e-1)" "unprognostic (2.87e-1)" "unprognostic (1.56e-1)" "unprognostic (1.41e-1)" "unprognostic (5.33e-3)" "unprognostic (2.21e-2)" "unprognostic (2.48e-3)" "unprognostic (4.29e-2)" "unprognostic (1.22e-3)" "unprognostic (1.84e-1)" "unprognostic (2.05e-1)" "unprognostic (1.84e-1)" "unprognostic (1.72e-1)" "unprognostic (1.11e-1)" "unprognostic (2.33e-1)" "unprognostic (1.51e-1)" "unprognostic (1.91e-2)" "unprognostic (1.82e-1)" "unprognostic (6.17e-2)" "unprognostic (9.41e-3)" "unprognostic (3.30e-2)" "unprognostic (3.53e-1)" "unprognostic (1.41e-1)" "unprognostic (1.45e-1)" "unprognostic (3.70e-3)" "unprognostic (3.73e-3)" C22orf31 "bK747E2.1, HS747E2A" ENSG00000100249 "Chromosome 22 open reading frame 31" O95567 22 29058672-29061831 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 4 "brain: 2.6;parathyroid gland: 2.9;testis: 8.4" "Cell type enhanced" "Detected in some" "Early spermatids: 111.2;Granulosa cells: 11.4;Late primary spermatocytes: 23.7;Late spermatids: 59.7;Retinal pigment epithelial cells: 8.5" "Cell type enhanced" "Detected in some" "astrocyte: 1.6;Bergmann glia: 1.8;fibroblast: 1.9;medium spiny neuron: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "cervical cancer: 1.3" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "HPA000604, HPA068522" Uncertain Approved "Nuclear membrane,Cytosol" NA NA "Cluster 67: Testis - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 32: Non-specific - Cell proliferation" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" "Nuclear membrane" Cytosol "HPA000604: , HPA068522: " C22orf39 MGC74441 ENSG00000242259 "Chromosome 22 open reading frame 39" Q6P5X5 22 19351368-19447711 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 46.3;Megakaryocytes: 74.2;Parietal cells: 58.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073701 Approved "Endoplasmic reticulum" "Intracellular and membrane" "No annotated function" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 97: Non-specific - Cellular respiration" 36 "Endoplasmic reticulum" "HPA073701: " "unprognostic (4.54e-2)" "unprognostic (3.87e-2)" "unprognostic (3.51e-1)" "unprognostic (3.50e-2)" "unprognostic (2.84e-1)" "unprognostic (4.98e-2)" "unprognostic (1.60e-1)" "unprognostic (2.43e-2)" "unprognostic (2.77e-1)" "unprognostic (1.64e-2)" "unprognostic (3.98e-2)" "unprognostic (1.04e-3)" "potential prognostic favorable (9.62e-4)" "unprognostic (4.70e-2)" "unprognostic (2.04e-3)" "unprognostic (7.74e-2)" "unprognostic (1.52e-2)" "unprognostic (5.63e-2)" "unprognostic (3.71e-3)" "unprognostic (2.38e-1)" "unprognostic (3.54e-1)" "unprognostic (2.16e-3)" "unprognostic (1.42e-1)" "unprognostic (4.54e-3)" "unprognostic (3.56e-3)" "unprognostic (7.91e-2)" "unprognostic (4.06e-2)" "unprognostic (1.93e-1)" "unprognostic (1.15e-1)" "unprognostic (1.37e-1)" "unprognostic (6.59e-2)" C22orf42 ENSG00000205856 "Chromosome 22 open reading frame 42" Q6IC83 22 32149006-32159322 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 11 "brain: 9.4;testis: 10.0" "Group enriched" "Detected in some" 8 "Early spermatids: 126.5;Late primary spermatocytes: 41.7;Late spermatids: 46.8" "Cell type enhanced" "Detected in some" "amygdala excitatory: 1.7;splatter: 2.7;thalamic excitatory: 3.0" "Group enriched" "Detected in some" 7 "Pancreatic Adenocarcinoma (TCGA): 1.4;Prostate Adenocarcinoma (TCGA): 1.5" "Region enhanced" "Detected in many" "hypothalamus: 23.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adrenal gland - Adrenal medulla cells, Pancreas - Alpha cells, Pancreas - Beta cells, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" HPA019531 Enhanced NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" "HPA019531: " "unprognostic (1.21e-2)" "unprognostic (1.60e-2)" C2CD2 "C21orf25, C21orf258, DKFZP586F0422, TMEM24L" ENSG00000157617 "C2 calcium dependent domain containing 2" Q9Y426 21 41885112-41954018 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 123.8" "Cell type enriched" "Detected in many" 4 "Adrenal cortex cells: 999.5" "Cell type enhanced" "Detected in all" "pericyte: 432.8;vascular associated smooth muscle cell: 290.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Enteric glia cells, Skeletal muscle - Endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030922, HPA030924" Enhanced Approved Nucleoplasm NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 18: Adrenal cortex cells - Steroidogensis" 1 Nucleoplasm "HPA030922: , HPA030924: " "unprognostic (2.91e-3)" "potential prognostic unfavorable (2.64e-4)" "unprognostic (3.99e-2)" "unprognostic (2.63e-2)" "unprognostic (4.28e-2)" "unprognostic (1.19e-1)" "unprognostic (1.03e-2)" "unprognostic (3.56e-2)" "unprognostic (1.01e-1)" "unprognostic (1.93e-1)" "unprognostic (1.20e-1)" "unprognostic (9.15e-2)" "unprognostic (1.77e-1)" "unprognostic (2.52e-2)" "unprognostic (8.88e-2)" "unprognostic (2.81e-2)" "unprognostic (3.12e-3)" "unprognostic (7.53e-2)" "unprognostic (2.57e-1)" "unprognostic (6.56e-2)" "unprognostic (1.26e-1)" "unprognostic (1.59e-1)" "unprognostic (3.78e-2)" "unprognostic (3.08e-1)" "unprognostic (1.68e-2)" "unprognostic (1.81e-2)" "unprognostic (4.82e-3)" "unprognostic (4.91e-2)" "unprognostic (2.17e-1)" "potential prognostic unfavorable (9.68e-4)" "unprognostic (2.38e-2)" C2CD2L "KIAA0285, TMEM24" ENSG00000172375 "C2CD2 like" O14523 11 119102198-119118544 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 32.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011044, HPA075369" Approved Supported "Plasma membrane" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 33: Neurons - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 36 "Plasma membrane" "HPA011044: , HPA075369: " "unprognostic (2.78e-1)" "unprognostic (3.20e-3)" "unprognostic (4.86e-2)" "unprognostic (4.31e-1)" "unprognostic (1.20e-3)" "unprognostic (7.15e-2)" "unprognostic (1.42e-1)" "unprognostic (4.23e-3)" "unprognostic (4.28e-2)" "unprognostic (2.30e-2)" "unprognostic (5.44e-3)" "unprognostic (1.37e-1)" "potential prognostic favorable (7.99e-4)" "unprognostic (1.31e-3)" "unprognostic (3.22e-2)" "unprognostic (2.28e-2)" "unprognostic (1.48e-1)" "unprognostic (1.09e-1)" "unprognostic (1.97e-1)" "unprognostic (4.53e-1)" "unprognostic (4.15e-1)" "unprognostic (4.84e-2)" "unprognostic (2.84e-1)" "unprognostic (5.03e-3)" "unprognostic (1.73e-1)" "unprognostic (1.02e-1)" "unprognostic (1.09e-2)" "unprognostic (4.08e-2)" "unprognostic (1.85e-3)" "unprognostic (2.92e-1)" "unprognostic (7.99e-2)" C2CD3 DKFZP586P0123 ENSG00000168014 "C2 domain containing 3 centriole elongation regulator" Q4AC94 11 74012718-74171210 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 122.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 21.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038552, HPA038553, HPA040433" Approved Supported "Nucleoplasm,Centrosome,Basal body,Acrosome,Equatorial segment,Principal piece" NA NA "Cluster 32: Basophils - Transcription" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 48: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 3 "Nucleoplasm, Centrosome, Basal body" "Acrosome, Equatorial segment, Principal piece" "HPA038552: , HPA038553: , HPA040433: " "unprognostic (9.70e-2)" "unprognostic (2.13e-1)" "unprognostic (1.14e-2)" "unprognostic (9.10e-2)" "unprognostic (6.85e-3)" "unprognostic (1.53e-1)" "unprognostic (1.57e-1)" "unprognostic (6.85e-2)" "unprognostic (1.98e-1)" "potential prognostic unfavorable (3.75e-4)" "potential prognostic unfavorable (5.87e-6)" "unprognostic (2.28e-1)" "unprognostic (2.05e-1)" "unprognostic (3.81e-2)" "unprognostic (2.78e-2)" "unprognostic (2.43e-1)" "unprognostic (6.29e-2)" "unprognostic (3.04e-2)" "unprognostic (6.12e-3)" "unprognostic (1.55e-2)" "unprognostic (2.34e-1)" "unprognostic (9.36e-3)" "unprognostic (5.44e-3)" "unprognostic (1.25e-2)" "unprognostic (1.24e-2)" "unprognostic (2.73e-3)" "unprognostic (1.99e-1)" "unprognostic (3.88e-2)" "unprognostic (2.65e-1)" "unprognostic (8.97e-2)" "unprognostic (1.31e-1)" C2CD4A "FAM148A, NLF1" ENSG00000198535 "C2 calcium dependent domain containing 4A" Q8NCU7 15 62066977-62070917 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "pituitary gland: 12.7" "Group enriched" "Detected in many" 6 "Endometrial glandular cells: 193.6;Pancreatic islet cells: 242.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 3.5" "Minor Salivary Gland - Minor salivary glandular cells" HPA078864 Supported Nucleoplasm,Nucleoli NA NA "Cluster 70: Non-specific - Protein processing" "Cluster 1: Neurons - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 51: Secretory epithelial cells - Mixed function" Nucleoplasm Nucleoli "HPA078864: " "unprognostic (5.61e-3)" "unprognostic (9.08e-2)" "unprognostic (2.62e-2)" "unprognostic (6.23e-3)" "unprognostic (3.95e-3)" "unprognostic (6.23e-2)" "unprognostic (1.63e-2)" "unprognostic (8.47e-3)" "unprognostic (4.51e-1)" "potential prognostic unfavorable (5.21e-6)" "unprognostic (5.20e-1)" "unprognostic (5.69e-3)" "unprognostic (4.22e-3)" "unprognostic (1.13e-1)" "unprognostic (1.06e-1)" "unprognostic (3.45e-2)" "unprognostic (4.25e-1)" "unprognostic (3.29e-2)" "unprognostic (7.73e-2)" "unprognostic (1.55e-1)" "unprognostic (3.21e-1)" "unprognostic (1.90e-3)" "unprognostic (9.44e-2)" "unprognostic (1.42e-2)" "unprognostic (6.73e-2)" "unprognostic (6.83e-2)" C2CD4B "FAM148B, NLF2" ENSG00000205502 "C2 calcium dependent domain containing 4B" A6NLJ0 15 62163535-62165285 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 95.2" "Cell type enhanced" "Detected in many" "Breast lactating cells: 133.5;Endometrial glandular cells: 193.6;Endometrial luminal cells: 76.9;Fallopian tube ciliated cells: 161.7;Gastric chief cells: 78.6;Lymphatic endothelial cells: 108.9;Medullary thymic epithelial cells: 91.2;Mucous neck cells: 77.9;Neuroendocrine cells: 130.1;Pancreatic acinar cells: 100.9;Pancreatic islet cells: 295.6;Tuft cells: 57.6;Vascular endothelial cells: 227.1" "Cell type enriched" "Detected in some" 38 "endothelial cell: 44.2" "Cancer enhanced" "Detected in many" "Stomach Adenocarcinoma (TCGA): 14.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 1.1;lung cancer: 1.7;ovarian cancer: 1.0" HPA046880 Uncertain NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "HPA046880: " "unprognostic (7.22e-2)" "unprognostic (6.49e-2)" "unprognostic (2.84e-3)" "unprognostic (2.11e-2)" "unprognostic (8.63e-2)" "unprognostic (9.00e-2)" "unprognostic (2.04e-3)" "unprognostic (8.77e-3)" "unprognostic (3.55e-2)" "unprognostic (1.74e-2)" "unprognostic (8.90e-2)" "unprognostic (2.47e-1)" "unprognostic (1.17e-2)" "unprognostic (1.64e-1)" "unprognostic (1.54e-1)" "unprognostic (1.15e-1)" "unprognostic (5.24e-2)" "unprognostic (9.79e-2)" "unprognostic (1.05e-2)" "unprognostic (9.76e-2)" "unprognostic (1.65e-1)" "unprognostic (5.77e-2)" "unprognostic (3.52e-2)" C2CD4C "FAM148C, KIAA1957, NLF3" ENSG00000183186 "C2 calcium dependent domain containing 4C" Q8TF44 19 405445-409147 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 27.0" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 5.2;Brain inhibitory neurons: 3.7;Fallopian secretory cells: 2.6;Lymphatic endothelial cells: 5.7;Medullary thymic epithelial cells: 2.4;Neuroendocrine cells: 4.3;Oligodendrocyte progenitor cells: 8.6;Other brain neurons: 17.7;Pituicytes/FSCs: 2.7;Rod photoreceptor cells: 4.0;Undifferentiated spermatogonia: 2.8;Vascular endothelial cells: 3.7" "Cell type enhanced" "Detected in many" "upper-layer intratelencephalic: 19.8" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 11.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA055915 Uncertain Approved "Vesicles,Microtubules,Primary cilium,Primary cilium tip,Basal body" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 1 "Vesicles, Primary cilium" "Microtubules, Primary cilium tip, Basal body" "HPA055915: " "unprognostic (1.91e-1)" "unprognostic (1.41e-3)" "unprognostic (6.91e-3)" "unprognostic (8.52e-2)" "potential prognostic favorable (3.92e-5)" "unprognostic (1.24e-1)" "unprognostic (1.46e-1)" "unprognostic (1.23e-1)" "unprognostic (6.01e-2)" "unprognostic (5.87e-2)" C2CD4D FAM148D ENSG00000225556 "C2 calcium dependent domain containing 4D" B7Z1M9 1 151837818-151840557 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.7;salivary gland: 1.7;skin 1: 2.2" "Cell type enhanced" "Detected in many" "Breast lactating cells: 7.9;Fallopian tube ciliated cells: 7.2;Innate lymphoid cells: 8.8;Medullary thymic epithelial cells: 7.2;Submucosal glandular cells: 5.8;Syncytiotrophoblasts: 13.4;Tuft cells: 23.1" "Cell type enhanced" "Detected in some" "oligodendrocyte: 3.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Minor Salivary Gland - Minor salivary glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 68: Non-specific - Basic cellular processes" "Cluster 53: Neurons - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" "unprognostic (1.88e-2)" "unprognostic (4.09e-3)" "unprognostic (5.73e-2)" "unprognostic (6.85e-2)" "unprognostic (2.88e-2)" "unprognostic (5.43e-2)" "unprognostic (2.54e-2)" "unprognostic (7.66e-2)" "unprognostic (1.42e-1)" "unprognostic (1.80e-1)" "unprognostic (1.13e-1)" "unprognostic (9.46e-2)" "unprognostic (1.85e-1)" "unprognostic (2.57e-1)" "unprognostic (1.36e-2)" C2CD5 "CDP138, KIAA0528" ENSG00000111731 "C2 calcium dependent domain containing 5" Q86YS7 12 22448583-22544546 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Lactotrophs: 317.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 88.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046194 Approved Supported "Centriolar satellite,Cytosol" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 37: Neurons - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 6 Cytosol "Centriolar satellite" "HPA046194: " "unprognostic (4.04e-2)" "unprognostic (1.54e-1)" "unprognostic (2.92e-1)" "unprognostic (7.69e-2)" "unprognostic (4.58e-1)" "unprognostic (1.67e-1)" "unprognostic (1.16e-3)" "unprognostic (1.87e-2)" "unprognostic (1.74e-1)" "unprognostic (6.67e-3)" "unprognostic (8.83e-3)" "unprognostic (9.09e-2)" "unprognostic (2.81e-3)" "unprognostic (2.15e-1)" "unprognostic (8.17e-2)" "unprognostic (4.50e-2)" "unprognostic (3.50e-1)" "unprognostic (3.19e-2)" "unprognostic (3.95e-2)" "unprognostic (3.46e-2)" "unprognostic (5.63e-2)" "unprognostic (3.40e-2)" "unprognostic (1.44e-3)" "unprognostic (2.95e-1)" "unprognostic (9.28e-2)" "unprognostic (5.07e-2)" "unprognostic (2.99e-1)" "unprognostic (1.44e-1)" "unprognostic (1.17e-3)" C2CD6 "ALS2CR11, FLJ25351" ENSG00000155754 "C2 calcium dependent domain containing 6" Q53TS8 2 201487421-201619178 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 30 "testis: 37.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 104.2;Choroid plexus epithelial cells: 73.3;Early spermatids: 267.9;Late primary spermatocytes: 399.1;Late spermatids: 289.6;Rod photoreceptor cells: 78.2;Somatotrophs: 155.5;Thyrotrophs: 87.0" "Cell type enhanced" "Detected in all" "oligodendrocyte: 96.8" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 3.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Adrenocortical cancer: 7.8" "Skeletal muscle - Fibroblasts, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA045406 Approved "Acrosome,Equatorial segment,Principal piece" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 30: White matter - Myelination" "Cluster 69: Skin cancer - ECM organization" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 44 "Principal piece" "Acrosome, Equatorial segment" "HPA045406: " "unprognostic (4.59e-3)" "unprognostic (1.05e-1)" "unprognostic (1.67e-2)" "unprognostic (4.43e-2)" "unprognostic (3.75e-2)" C2orf15 MGC29762 ENSG00000273045 "Chromosome 2 open reading frame 15" Q8WU43 2 99141707-99151669 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Corticotrophs: 2.0;Epididymal efferent duct absorptive cells: 1.5;Epididymal efferent duct ciliated cells: 2.1;Epididymal principal cells: 1.5;Fallopian secretory cells: 1.3;Fallopian tube ciliated cells: 1.5;Mucous neck cells: 1.6;Paneth cells: 3.9;pDCs: 1.3;Prostatic club cells: 1.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Prostate - Prostate basal glandular cells, Spleen - B-cells (Spleen), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 22: Epididymis - Mixed function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 20: Non-specific - Transcription regulation" 5 "unprognostic (5.19e-2)" "unprognostic (8.75e-2)" "unprognostic (7.32e-2)" "unprognostic (1.29e-1)" "unprognostic (1.04e-1)" "unprognostic (1.75e-1)" "unprognostic (2.75e-1)" "unprognostic (4.25e-2)" "unprognostic (1.53e-1)" "unprognostic (3.74e-3)" "unprognostic (1.93e-1)" "unprognostic (4.29e-2)" "unprognostic (7.26e-2)" "unprognostic (9.02e-2)" "unprognostic (1.30e-1)" "unprognostic (1.87e-2)" "unprognostic (3.54e-2)" "unprognostic (1.80e-2)" "unprognostic (2.77e-2)" "unprognostic (1.89e-2)" "unprognostic (1.33e-1)" "potential prognostic favorable (7.75e-5)" "unprognostic (1.26e-1)" "unprognostic (3.45e-2)" "unprognostic (2.66e-1)" "unprognostic (3.59e-2)" "unprognostic (3.80e-2)" C2orf16 DKFZp434G118 ENSG00000221843 "Chromosome 2 open reading frame 16" 2 27537386-27582722 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 7 "testis: 10.1" "Cell type enriched" "Detected in some" 4 "Early spermatids: 476.0" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA052136, HPA056962" Uncertain Approved "Nucleoplasm,Nuclear bodies,Cytosol" No No "Cluster 79: Testis - Spermatogenesis" "Cluster 24: Neurons - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" "Nuclear bodies" "Nucleoplasm, Cytosol" "HPA052136: , HPA056962: " "unprognostic (9.42e-2)" "potential prognostic favorable (5.23e-4)" C2orf42 FLJ20558 ENSG00000115998 "Chromosome 2 open reading frame 42" Q9NWW7 2 70149885-70248615 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 55.2" "Cell type enhanced" "Detected in many" "Early spermatids: 263.4;Late primary spermatocytes: 216.7;Late spermatids: 141.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031840, HPA031841, HPA031842" Enhanced Enhanced Nucleoplasm NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 47: Testis - Mixed function" "Cluster 55: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 4 Nucleoplasm "HPA031840: , HPA031841: , HPA031842: " "unprognostic (2.75e-1)" "unprognostic (1.46e-3)" "unprognostic (3.19e-2)" "unprognostic (4.19e-2)" "unprognostic (6.63e-3)" "unprognostic (7.36e-2)" "unprognostic (3.55e-1)" "unprognostic (1.03e-3)" "unprognostic (1.29e-1)" "potential prognostic unfavorable (6.43e-4)" "potential prognostic favorable (3.67e-6)" "unprognostic (2.57e-2)" "unprognostic (7.66e-2)" "unprognostic (1.62e-1)" "unprognostic (1.22e-1)" "unprognostic (3.94e-2)" "unprognostic (1.12e-1)" "unprognostic (2.67e-2)" "unprognostic (6.46e-2)" "unprognostic (2.62e-2)" "unprognostic (2.19e-3)" "potential prognostic favorable (3.31e-4)" "unprognostic (2.91e-2)" "unprognostic (2.78e-1)" "unprognostic (6.67e-2)" "unprognostic (5.68e-2)" "unprognostic (6.72e-2)" "unprognostic (5.65e-2)" "unprognostic (2.80e-1)" "unprognostic (1.56e-1)" "unprognostic (2.07e-2)" C2orf49 "asw, MGC5509" ENSG00000135974 "Chromosome 2 open reading frame 49" Q9BVC5 2 105337532-105349211 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043846, HPA060814" Approved Supported Nucleoplasm NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 40: Non-specific - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 17: Non-specific - RNA processing" 23 Nucleoplasm "HPA043846: , HPA060814: " "unprognostic (1.21e-1)" "unprognostic (2.37e-2)" "unprognostic (4.72e-2)" "potential prognostic unfavorable (9.19e-4)" "unprognostic (6.22e-2)" "unprognostic (7.63e-2)" "unprognostic (3.15e-2)" "unprognostic (5.24e-2)" "unprognostic (1.49e-3)" "potential prognostic unfavorable (9.23e-4)" "potential prognostic favorable (5.04e-5)" "unprognostic (2.21e-2)" "unprognostic (4.01e-3)" "unprognostic (9.45e-3)" "unprognostic (2.12e-2)" "unprognostic (1.19e-1)" "unprognostic (3.19e-1)" "unprognostic (1.54e-2)" "unprognostic (8.31e-2)" "unprognostic (4.70e-2)" "unprognostic (1.60e-2)" "unprognostic (1.71e-2)" "potential prognostic unfavorable (1.91e-4)" "unprognostic (1.36e-1)" "unprognostic (2.04e-3)" "unprognostic (5.92e-2)" "unprognostic (5.04e-2)" "unprognostic (2.89e-2)" "unprognostic (1.43e-1)" "unprognostic (8.29e-2)" "unprognostic (1.17e-1)" C2orf50 FLJ25143 ENSG00000150873 "Chromosome 2 open reading frame 50" Q96LR7 2 11133128-11151317 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "choroid plexus: 6.0;fallopian tube: 7.0" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 31.7;Endometrial ciliated cells: 60.4;Ependymal cells: 64.4;Epididymal efferent duct ciliated cells: 56.7;Fallopian tube ciliated cells: 119.5;Respiratory ciliated cells: 138.0;Respiratory deuterosomal cells: 24.9;Rod photoreceptor cells: 20.4" "Cell type enhanced" "Detected in many" "ependymal cell: 72.7" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 5.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 1.7" "Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary gland ductal cells" "HPA062894, HPA067681" Enhanced Approved "Golgi apparatus,Cytosol" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 27: Breast cancer - Unknown function" "Cluster 107: Ciliated cells - Cilia assembly & function" 7 "Golgi apparatus" Cytosol "HPA062894: , HPA067681: " "unprognostic (1.38e-1)" "unprognostic (5.07e-2)" "unprognostic (4.40e-2)" "unprognostic (2.98e-1)" "unprognostic (4.65e-2)" "potential prognostic unfavorable (4.64e-4)" "unprognostic (1.01e-1)" "unprognostic (2.56e-1)" "unprognostic (6.75e-3)" "unprognostic (4.54e-2)" "unprognostic (5.56e-1)" "unprognostic (1.99e-1)" C2orf66 UNQ6411 ENSG00000187944 "Chromosome 2 open reading frame 66" 2 196804417-196809355 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "adrenal gland: 9.8;brain: 4.7;pituitary gland: 7.3" "Cell type enriched" "Detected in some" 6 "Early spermatids: 57.8" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in single" "Glioblastoma Multiforme (TCGA): 2.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA020869 Uncertain Uncertain Nucleoplasm,Cytosol "Secreted - unknown location" NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" Nucleoplasm Cytosol "HPA020869: " "unprognostic (2.51e-1)" "unprognostic (1.01e-1)" "unprognostic (7.66e-2)" C2orf68 ENSG00000168887 "Chromosome 2 open reading frame 68" Q2NKX9 2 85605254-85612066 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051143 Uncertain Approved "Nucleoplasm,Nuclear membrane,Nucleoli,Mitochondria" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 11 "Nucleoplasm, Nuclear membrane, Mitochondria" Nucleoli "HPA051143: " "unprognostic (1.40e-2)" "unprognostic (5.65e-2)" "unprognostic (9.18e-2)" "unprognostic (3.75e-1)" "unprognostic (2.31e-3)" "unprognostic (3.17e-1)" "unprognostic (2.34e-1)" "unprognostic (1.45e-3)" "unprognostic (1.28e-1)" "unprognostic (2.98e-1)" "unprognostic (1.45e-2)" "unprognostic (1.78e-1)" "unprognostic (3.60e-1)" "potential prognostic unfavorable (1.03e-5)" "unprognostic (2.01e-3)" "unprognostic (2.28e-1)" "unprognostic (2.74e-1)" "unprognostic (9.90e-3)" "unprognostic (1.70e-2)" "unprognostic (3.44e-2)" "unprognostic (1.88e-1)" "unprognostic (1.44e-2)" "unprognostic (1.85e-2)" "unprognostic (9.93e-2)" "unprognostic (6.72e-3)" "unprognostic (4.75e-2)" "unprognostic (6.22e-2)" "unprognostic (1.63e-1)" "unprognostic (1.20e-1)" "unprognostic (6.55e-2)" "unprognostic (1.81e-1)" C2orf69 FLJ38973 ENSG00000178074 "Chromosome 2 open reading frame 69" Q8N8R5 2 199911293-199955935 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 111.0;Early primary spermatocytes: 92.7;Early spermatids: 109.2;Late primary spermatocytes: 139.7;Late spermatids: 114.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045225 Approved "Intracellular and membrane" Transport NA Yes "Cluster 24: Non-specific - Transcription" "Cluster 73: Brain - Neuronal signaling" "Cluster 31: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "HPA045225: " "unprognostic (2.12e-3)" "unprognostic (3.75e-2)" "unprognostic (2.92e-1)" "unprognostic (5.37e-2)" "unprognostic (3.49e-2)" "unprognostic (3.52e-2)" "unprognostic (2.10e-1)" "unprognostic (2.24e-1)" "unprognostic (1.64e-1)" "unprognostic (1.07e-2)" "potential prognostic favorable (1.24e-4)" "unprognostic (6.39e-2)" "unprognostic (1.10e-2)" "unprognostic (1.64e-3)" "unprognostic (2.84e-2)" "unprognostic (8.63e-2)" "unprognostic (6.92e-2)" "unprognostic (1.37e-2)" "unprognostic (8.18e-2)" "unprognostic (3.75e-2)" "unprognostic (1.18e-1)" "unprognostic (8.31e-2)" "unprognostic (2.20e-2)" "unprognostic (2.19e-1)" "unprognostic (5.71e-2)" "unprognostic (1.70e-1)" "unprognostic (5.33e-2)" "unprognostic (3.22e-2)" "unprognostic (1.36e-1)" "unprognostic (3.86e-3)" "unprognostic (2.22e-1)" C2orf72 LOC257407 ENSG00000204128 "Chromosome 2 open reading frame 72" A6NCS6 2 231037523-231049719 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 5.9;liver: 18.9" "Cell type enhanced" "Detected in many" "Astrocytes: 233.5;Bergmann glia: 66.4;Brain excitatory neurons: 37.4;Cholangiocytes: 53.4;Colonocytes: 40.6;Hepatocytes: 171.3;Late spermatids: 66.8;Oligodendrocyte progenitor cells: 81.2" "Cell type enhanced" "Detected in all" "astrocyte: 269.8" "Group enriched" "Detected in some" 5 "Glioblastoma Multiforme (TCGA): 2.3;Liver Hepatocellular Carcinoma (TCGA): 3.7;Prostate Adenocarcinoma (TCGA): 1.9;Stomach Adenocarcinoma (TCGA): 7.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 3.2;liver cancer: 4.5" "Adrenal gland - Adrenal medulla cells, Breast - Breast glandular cells, Liver - Hepatocytes, Pituitary gland - Corticotropes, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044962 Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 28: Astrocytes - Homeostasis & neuron support" 3 "Nucleoplasm, Plasma membrane" "HPA044962: " "unprognostic (2.22e-2)" "unprognostic (2.32e-1)" "unprognostic (1.59e-1)" "unprognostic (1.95e-3)" "unprognostic (1.77e-1)" "unprognostic (1.13e-1)" "unprognostic (1.85e-1)" "unprognostic (7.49e-2)" "unprognostic (1.85e-2)" "unprognostic (1.29e-1)" "unprognostic (9.51e-3)" "unprognostic (4.02e-2)" C2orf73 FLJ40298 ENSG00000177994 "Chromosome 2 open reading frame 73" Q8N5S3 2 54330034-54383742 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 46.3" "Group enriched" "Detected in many" 4 "Early spermatids: 1278.6;Late primary spermatocytes: 534.4;Late spermatids: 738.4" "Group enriched" "Detected in many" 7 "choroid plexus epithelial cell: 149.0;ependymal cell: 224.4" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Enteric glia cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA055221, HPA059596" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 5: Rhabdoid - Unknown function" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" Nucleoplasm "Plasma membrane, Cytosol" "HPA055221: , HPA059596: " "unprognostic (5.18e-3)" "unprognostic (5.02e-2)" "unprognostic (2.99e-1)" C2orf74 LOC339804 ENSG00000237651 "Chromosome 2 open reading frame 74" A8MZ97 2 61145068-61164828 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 16.6;Bergmann glia: 16.5;Brain excitatory neurons: 20.8;Brain inhibitory neurons: 20.0;Early spermatids: 19.6;Ependymal cells: 16.5;Epididymal principal cells: 14.0;Loop of henle epithelial cells: 16.5;Microglia: 18.1;Oligodendrocytes: 19.7;Other brain neurons: 25.5;Papillary tip epithelial cells: 13.7;Podocytes: 13.4;Proximal tubule cells: 17.6;Renal collecting duct principal cells: 12.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA026826 Approved Approved Centrosome NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 36: Brain & Liver - Signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 98: Neurons - Neurotransmission & signaling" 1 Centrosome "HPA026826: " "unprognostic (6.53e-3)" "unprognostic (3.25e-2)" "unprognostic (1.45e-1)" "unprognostic (1.74e-1)" "unprognostic (2.77e-3)" "unprognostic (2.26e-1)" "unprognostic (7.62e-2)" "unprognostic (1.05e-1)" "unprognostic (2.85e-1)" "unprognostic (1.22e-2)" "unprognostic (5.33e-3)" "unprognostic (2.24e-1)" "unprognostic (3.00e-2)" "unprognostic (8.28e-2)" "unprognostic (5.19e-2)" "unprognostic (1.49e-1)" "unprognostic (5.97e-2)" "unprognostic (2.62e-1)" "unprognostic (1.80e-1)" "potential prognostic favorable (1.98e-4)" "unprognostic (1.48e-2)" "unprognostic (3.92e-1)" "unprognostic (2.22e-1)" "unprognostic (8.05e-2)" "unprognostic (1.24e-1)" "unprognostic (6.25e-3)" "unprognostic (3.56e-1)" "unprognostic (2.73e-2)" "unprognostic (3.08e-1)" "unprognostic (1.69e-1)" "unprognostic (2.09e-1)" C2orf76 "AIM29, LOC130355, MGC104437" ENSG00000186132 "Chromosome 2 open reading frame 76" Q3KRA6 2 119302225-119366834 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 175.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "HPA044977, HPA055362" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 22: Epididymis - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 97: Non-specific - Cellular respiration" "Endoplasmic reticulum" "HPA044977: , HPA055362: " "unprognostic (1.75e-2)" "unprognostic (1.31e-1)" "unprognostic (1.71e-2)" "unprognostic (1.82e-1)" "unprognostic (1.65e-2)" "unprognostic (5.97e-2)" "unprognostic (4.30e-2)" "unprognostic (2.16e-1)" "unprognostic (7.39e-3)" "unprognostic (2.95e-1)" "unprognostic (5.73e-2)" "unprognostic (2.22e-1)" "unprognostic (1.26e-1)" "unprognostic (1.34e-3)" "unprognostic (3.80e-3)" "unprognostic (6.80e-2)" "unprognostic (4.81e-1)" "unprognostic (7.96e-3)" "unprognostic (6.57e-2)" "unprognostic (7.40e-2)" "unprognostic (1.13e-1)" "unprognostic (1.96e-1)" "potential prognostic unfavorable (6.34e-5)" "unprognostic (6.02e-2)" "unprognostic (2.02e-1)" "unprognostic (2.30e-2)" "potential prognostic unfavorable (7.21e-4)" "unprognostic (6.13e-2)" "unprognostic (2.59e-2)" "unprognostic (4.08e-1)" "unprognostic (4.44e-1)" C2orf78 "COG5373, FLJ43987, hCG1989538" ENSG00000187833 "Chromosome 2 open reading frame 78" A6NCI8 2 73784183-73817148 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 119 "testis: 11.9" "Group enriched" "Detected in some" 6 "Early spermatids: 59.2;Late primary spermatocytes: 43.8" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 6 "cerebral cortex: 1.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA073368 Uncertain Nucleoplasm NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 53: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" Nucleoplasm "HPA073368: " C2orf80 "GONDA1, LOC389073" ENSG00000188674 "Chromosome 2 open reading frame 80" Q0P641 2 208165343-208190030 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 9 "brain: 39.6" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 28.8;Brain inhibitory neurons: 29.8;Breast lactating cells: 10.3;Oligodendrocyte progenitor cells: 44.7;Other brain neurons: 30.7" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in some" 22 "Glioblastoma Multiforme (TCGA): 27.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.2" "Lineage enriched" "Detected in single" 5 "granulocytes: 4.2" "Not detected" "Not detected" "Colon - Colon enteroendocrine cells, Pituitary gland - Thyrotropes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA042639 Approved "Golgi apparatus" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 78: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 56: Non-specific - Sensory perception" "Cluster 98: Neurons - Neurotransmission & signaling" "Golgi apparatus" "HPA042639: " "unprognostic (3.97e-2)" "unprognostic (4.85e-2)" "unprognostic (3.61e-1)" "unprognostic (1.05e-1)" "unprognostic (1.04e-1)" "unprognostic (1.00e-1)" C2orf81 "hCG40743, LOC388963" ENSG00000284308 "Chromosome 2 open reading frame 81" A6NN90 2 74414176-74421619 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 18.1;testis: 17.6" "Cell type enriched" "Detected in some" 4 "Ependymal cells: 96.7" "Cell type enriched" "Detected in many" 4 "ependymal cell: 114.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 13.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049564, HPA054835" Enhanced Approved "Nucleoplasm,Nucleoli,Nucleoli fibrillar center" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" "Nucleoplasm, Nucleoli, Nucleoli fibrillar center" "HPA049564: , HPA054835: " "unprognostic (4.28e-2)" "unprognostic (1.51e-1)" "unprognostic (1.97e-1)" "unprognostic (2.26e-1)" "unprognostic (8.64e-2)" "unprognostic (1.74e-1)" "unprognostic (1.42e-2)" "unprognostic (3.84e-2)" "unprognostic (1.14e-1)" "unprognostic (6.70e-2)" "unprognostic (3.68e-2)" "potential prognostic favorable (3.61e-4)" "unprognostic (1.57e-2)" "unprognostic (6.25e-2)" "unprognostic (2.93e-1)" "unprognostic (2.99e-1)" "unprognostic (2.64e-2)" "unprognostic (1.46e-3)" "unprognostic (1.17e-1)" "unprognostic (8.05e-2)" "unprognostic (3.34e-1)" "unprognostic (3.52e-3)" "unprognostic (4.15e-1)" "unprognostic (1.05e-1)" "unprognostic (2.13e-1)" "unprognostic (5.58e-3)" C2orf88 "MGC13057, smAKAP" ENSG00000187699 "Chromosome 2 open reading frame 88" Q9BSF0 2 189879609-190203484 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 68.6" "Cell type enhanced" "Detected in many" "Colonocytes: 361.4;Early spermatids: 1540.4;Endometrial luminal cells: 327.4;Enterocytes: 442.7;Epicardial cells: 382.1;Late spermatids: 1845.1;Megakaryocytes: 537.8;Platelets: 1847.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Ovary Serous Cystadenocarcinoma (TCGA): 35.5;Uterine Corpus Endometrial Carcinoma (TCGA): 47.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory B-cell: 2.7;naive B-cell: 2.9;neutrophil: 7.3;plasmacytoid DC: 3.0" "Group enriched" "Detected in many" 8 "B-cells: 2.9;dendritic cells: 3.0;granulocytes: 7.3" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Colon - Enteric glia cells, Liver - Sinusoid Endothelial cells, Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049549 Approved NA NA 62000 "Cluster 20: Non-specific - DNA binding" "Cluster 21: Testis - Mixed function" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 3 "HPA049549: " "unprognostic (2.39e-3)" "potential prognostic favorable (8.83e-6)" "unprognostic (6.13e-2)" "unprognostic (4.67e-1)" "unprognostic (4.71e-2)" "unprognostic (1.91e-2)" "unprognostic (1.41e-2)" "unprognostic (1.19e-1)" "unprognostic (9.28e-3)" "unprognostic (2.92e-1)" "potential prognostic favorable (3.07e-5)" "unprognostic (1.41e-2)" "unprognostic (3.28e-2)" "unprognostic (1.21e-1)" "unprognostic (6.49e-2)" "unprognostic (1.61e-1)" "unprognostic (6.61e-2)" "unprognostic (1.32e-1)" "unprognostic (3.37e-2)" "unprognostic (1.86e-2)" "unprognostic (7.36e-3)" "unprognostic (5.88e-2)" "potential prognostic favorable (1.95e-4)" "unprognostic (1.54e-1)" "unprognostic (1.47e-1)" "unprognostic (1.03e-2)" "potential prognostic unfavorable (1.86e-5)" "unprognostic (9.70e-3)" "unprognostic (7.17e-2)" "unprognostic (7.37e-2)" "unprognostic (1.15e-1)" C2orf92 LINC01125 ENSG00000228486 "Chromosome 2 open reading frame 92" A0A1B0GVN3 2 97664217-97703066 "Essential proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "choroid plexus: 13.3;testis: 11.2" "Cell type enhanced" "Detected in many" "Early spermatids: 247.1;Late primary spermatocytes: 171.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Breast glandular cells, Colon - Enteric glia cells, Skeletal muscle - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 11: White matter - Signal transduction" "Cluster 35: RS4;11 - Unknown function" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" "unprognostic (1.04e-1)" "unprognostic (7.88e-2)" "unprognostic (9.18e-2)" "unprognostic (1.83e-1)" C3 "ARMD9, C3a, C3b, CPAMD1" ENSG00000125730 "Complement C3" P01024 19 6677704-6730562 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement alternate pathway, Complement pathway, Fatty acid metabolism, Immunity, Inflammatory response, Innate immunity, Lipid metabolism" "Age-related macular degeneration, Disease variant, FDA approved drug targets, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "liver: 5062.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 600.4;Cholangiocytes: 820.3;Conjunctival goblet cells: 549.5;Decidual stromal cells: 714.5;Endometrial secretory cells: 578.5;Epicardial cells: 755.0;Fibroblasts: 641.5;Hepatocytes: 4896.9;Lacrimal acinar cells: 537.2;Mesothelial cells: 1368.4;Microglia: 649.7;Pancreatic duct cells: 642.3" "Cell type enriched" "Detected in many" 49 "central nervous system macrophage: 753.0" "Cancer enriched" "Detected in all" 4 "Liver Hepatocellular Carcinoma (TCGA): 2548.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "non-classical monocyte: 14.5" "Lineage enriched" "Detected in many" 5 "monocytes: 14.5" "Cancer enhanced" "Detected in many" "liver cancer: 255.0" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Lung - Fibroblasts_2, Stomach - Fibroblasts, Thyroid gland - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA003563, CAB004209, HPA020432" Enhanced "Secreted to blood" "Complement pathway" NA NA 1260000000000 370000000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 42 "CAB004209: , HPA003563: , HPA020432: " "potential prognostic favorable (1.46e-4)" "unprognostic (3.99e-3)" "unprognostic (2.04e-2)" "unprognostic (6.44e-2)" "unprognostic (6.78e-2)" "unprognostic (8.30e-2)" "unprognostic (2.71e-2)" "unprognostic (3.60e-1)" "unprognostic (8.21e-2)" "unprognostic (1.92e-1)" "unprognostic (4.25e-2)" "unprognostic (2.11e-1)" "unprognostic (2.98e-1)" "unprognostic (2.64e-3)" "potential prognostic favorable (2.99e-6)" "unprognostic (1.82e-1)" "unprognostic (3.09e-3)" "unprognostic (7.40e-3)" "unprognostic (6.78e-2)" "unprognostic (2.39e-1)" "unprognostic (3.19e-1)" "unprognostic (8.47e-3)" "unprognostic (3.71e-2)" "unprognostic (7.20e-2)" "unprognostic (1.04e-1)" "unprognostic (8.27e-3)" "unprognostic (1.93e-1)" "unprognostic (2.03e-2)" "unprognostic (1.65e-2)" "unprognostic (1.35e-2)" "unprognostic (5.99e-2)" C3AR1 "AZ3B, C3AR" ENSG00000171860 "Complement C3a receptor 1" Q16581 12 8056844-8066359 "G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 37.8" "Cell type enhanced" "Detected in some" "Hofbauer cells: 283.3;Kupffer cells: 222.4;Macrophages: 206.2;Mast cells: 71.2;Microglia: 79.2;monocytes: 217.9;Neutrophil progenitors: 196.5;Neutrophils: 371.4" "Cell type enriched" "Detected in some" 9 "central nervous system macrophage: 99.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 902.8;eosinophil: 452.5;intermediate monocyte: 274.2;non-classical monocyte: 373.1" "Group enriched" "Detected in many" 20 "granulocytes: 902.8;monocytes: 373.1" "Cancer enhanced" "Detected in some" "Leukemia: 5.8" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Lung - Macrophages, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in many" CAB009405 Enhanced NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" "CAB009405: " "unprognostic (1.10e-1)" "unprognostic (1.42e-2)" "unprognostic (2.58e-1)" "unprognostic (8.13e-2)" "unprognostic (1.71e-1)" "unprognostic (6.66e-2)" "unprognostic (4.59e-2)" "unprognostic (1.41e-1)" "unprognostic (9.20e-2)" "unprognostic (2.69e-1)" "unprognostic (3.47e-3)" "unprognostic (9.90e-2)" "potential prognostic favorable (3.17e-4)" "unprognostic (2.35e-2)" "unprognostic (7.29e-2)" "unprognostic (1.26e-2)" "unprognostic (8.67e-3)" "unprognostic (8.30e-2)" "unprognostic (6.55e-3)" "potential prognostic unfavorable (4.15e-4)" "unprognostic (2.01e-1)" "unprognostic (1.08e-1)" "unprognostic (1.00e-1)" "unprognostic (2.73e-2)" "unprognostic (3.16e-2)" "unprognostic (9.23e-3)" "unprognostic (1.75e-2)" "unprognostic (3.53e-2)" "unprognostic (6.40e-3)" "unprognostic (5.94e-2)" "unprognostic (1.21e-1)" C3orf14 HT021 ENSG00000114405 "Chromosome 3 open reading frame 14" Q9HBI5 3 62319015-62336213 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 59.2" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 122.0;Early primary spermatocytes: 158.5;Early spermatids: 129.8;Late primary spermatocytes: 196.3;Oocytes: 96.7;Pancreatic islet cells: 98.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 28.3" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Prostate - Prostate glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048286 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 73: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 8 "Plasma membrane" Cytosol "HPA048286: " "unprognostic (1.32e-2)" "unprognostic (4.03e-2)" "unprognostic (4.94e-2)" "unprognostic (1.12e-1)" "unprognostic (2.66e-1)" "unprognostic (5.97e-2)" "unprognostic (6.91e-3)" "unprognostic (3.83e-2)" "unprognostic (1.32e-1)" "unprognostic (3.47e-2)" "unprognostic (1.58e-2)" "unprognostic (3.09e-1)" "unprognostic (6.15e-2)" "potential prognostic unfavorable (6.70e-5)" "unprognostic (1.75e-2)" "unprognostic (2.48e-1)" "unprognostic (2.91e-3)" "unprognostic (3.43e-3)" "unprognostic (2.43e-1)" "unprognostic (9.33e-2)" "unprognostic (9.11e-2)" "unprognostic (3.64e-1)" "unprognostic (2.13e-1)" "unprognostic (2.64e-1)" "unprognostic (1.18e-1)" "unprognostic (1.88e-2)" "unprognostic (2.53e-1)" "unprognostic (1.94e-2)" "unprognostic (1.46e-1)" "unprognostic (4.51e-2)" "unprognostic (7.32e-2)" C3orf18 G20 ENSG00000088543 "Chromosome 3 open reading frame 18" Q9UK00 3 50558025-50571027 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 54.9" "Group enriched" "Detected in many" 4 "Cardiomyocytes: 53.3;Early spermatids: 65.3;Late spermatids: 105.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 35.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 2.2;NK-cells: 2.0;T-cells: 6.3" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Testis - Late spermatids" "Group enriched" "Detected in all" 4 "cerebellum: 28.2;olfactory bulb: 27.5" "Low region specificity" "Detected in all" HPA012105 Approved Approved Cytosol No No "Cluster 43: Non-specific - Transcription & Translation" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 2: Neurons - Nucleosome" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 11 Cytosol "HPA012105: " "unprognostic (3.86e-2)" "unprognostic (4.22e-2)" "potential prognostic favorable (7.46e-4)" "unprognostic (2.31e-2)" "unprognostic (1.50e-2)" "unprognostic (2.51e-2)" "unprognostic (5.68e-2)" "unprognostic (3.24e-2)" "unprognostic (3.83e-1)" "unprognostic (6.88e-2)" "unprognostic (2.41e-3)" "unprognostic (1.80e-1)" "potential prognostic favorable (3.59e-5)" "unprognostic (1.44e-1)" "unprognostic (3.79e-2)" "potential prognostic favorable (3.24e-4)" "unprognostic (1.64e-1)" "unprognostic (2.17e-3)" "unprognostic (1.18e-1)" "unprognostic (1.11e-1)" "unprognostic (2.80e-2)" "unprognostic (2.82e-3)" "unprognostic (3.74e-1)" "unprognostic (6.12e-2)" "unprognostic (3.48e-2)" "unprognostic (2.30e-1)" "unprognostic (6.38e-2)" "unprognostic (1.47e-2)" "unprognostic (3.35e-1)" "unprognostic (3.32e-1)" "unprognostic (6.05e-2)" C3orf20 DKFZP434N1817 ENSG00000131379 "Chromosome 3 open reading frame 20" Q8ND61 3 14675141-14773036 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 16 "testis: 6.2" "Cell type enhanced" "Detected in many" "Early spermatids: 28.1;Late primary spermatocytes: 22.9;Late spermatids: 64.6;Neutrophils: 30.1" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lymphoma: 1.7" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" HPA039584 Uncertain Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 37: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 1 "Plasma membrane, Cytosol" "HPA039584: " "unprognostic (1.70e-1)" C3orf22 MGC34728 ENSG00000180697 "Chromosome 3 open reading frame 22" Q8N5N4 3 126526999-126558965 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 481 "testis: 48.1" "Cell type enriched" "Detected in some" 7 "Late spermatids: 3096.0" "Low cell type specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA059199 Enhanced NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" "HPA059199: " C3orf33 "AC3-33, FLJ31139" ENSG00000174928 "Chromosome 3 open reading frame 33" Q6P1S2 3 155762617-155806278 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 17.9;Bergmann glia: 27.2;Brain excitatory neurons: 23.9;Brain inhibitory neurons: 22.0;Choroid plexus epithelial cells: 17.2;Ependymal cells: 25.9;Oligodendrocyte progenitor cells: 21.0;Oligodendrocytes: 16.8;Oocytes: 27.6;Other brain neurons: 24.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" HPA037663 Uncertain "Secreted in other tissues" "No annotated function" NA NA "Cluster 27: T-cells - Unknown function" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 98: Neurons - Neurotransmission & signaling" 4 "HPA037663: " "unprognostic (5.01e-2)" "unprognostic (2.93e-2)" "unprognostic (1.68e-1)" "unprognostic (4.37e-1)" "unprognostic (2.15e-3)" "unprognostic (2.22e-1)" "unprognostic (5.71e-2)" "unprognostic (9.93e-2)" "unprognostic (1.19e-1)" "unprognostic (8.10e-2)" "unprognostic (2.65e-2)" "unprognostic (1.06e-1)" "unprognostic (1.14e-2)" "unprognostic (1.23e-3)" "unprognostic (2.28e-3)" "unprognostic (1.32e-3)" "unprognostic (1.12e-1)" "unprognostic (5.58e-2)" "unprognostic (8.74e-3)" "unprognostic (7.10e-2)" "unprognostic (6.56e-2)" "unprognostic (4.98e-3)" "unprognostic (1.38e-1)" "unprognostic (3.49e-1)" "unprognostic (5.78e-2)" "unprognostic (2.10e-1)" "unprognostic (1.77e-1)" "unprognostic (8.42e-2)" "unprognostic (2.07e-1)" "unprognostic (3.85e-2)" "unprognostic (3.00e-1)" C3orf38 MGC26717 ENSG00000179021 "Chromosome 3 open reading frame 38" Q5JPI3 3 88149959-88168729 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 306.6;Late primary spermatocytes: 289.1;Late spermatids: 500.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034736, HPA034737" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 13: Non-specific - Mixed function" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 1 "Plasma membrane, Cytosol" Nucleoplasm "HPA034736: , HPA034737: " "unprognostic (9.60e-2)" "unprognostic (3.46e-1)" "unprognostic (1.16e-1)" "potential prognostic unfavorable (4.74e-4)" "unprognostic (4.40e-2)" "potential prognostic unfavorable (8.67e-4)" "unprognostic (4.64e-3)" "unprognostic (4.68e-2)" "unprognostic (1.54e-1)" "unprognostic (4.19e-3)" "potential prognostic favorable (2.87e-6)" "unprognostic (6.45e-2)" "unprognostic (2.67e-1)" "potential prognostic unfavorable (2.30e-6)" "unprognostic (4.85e-2)" "unprognostic (1.94e-1)" "unprognostic (2.05e-2)" "unprognostic (1.97e-1)" "unprognostic (8.78e-2)" "unprognostic (1.54e-2)" "unprognostic (7.10e-2)" "unprognostic (1.01e-2)" "unprognostic (7.19e-3)" "potential prognostic unfavorable (9.04e-4)" "unprognostic (3.43e-2)" "unprognostic (7.47e-2)" "unprognostic (1.97e-1)" "unprognostic (7.37e-2)" "unprognostic (5.89e-2)" "unprognostic (1.01e-1)" "unprognostic (2.04e-1)" C3orf49 ENSG00000163632 "Chromosome 3 open reading frame 49" Q96BT1 3 63819299-63848636 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Adipocytes: 23.5;Cardiomyocytes: 43.2;Early spermatids: 27.5;Epicardial cells: 15.9;Fibro-adipogenic progenitors: 16.1;Late spermatids: 50.1;Myonuclei: 32.6;Myosatellite cells: 16.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA053582 Uncertain Approved Vesicles,Centrosome,Cytosol NA NA "Cluster 40: Non-specific - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" Cytosol "Vesicles, Centrosome" "HPA053582: " "unprognostic (1.40e-1)" "unprognostic (6.10e-2)" "potential prognostic unfavorable (3.91e-4)" C3orf52 "FLJ23186, TTMP" ENSG00000114529 "Chromosome 3 open reading frame 52" Q5BVD1 3 112086335-112131004 "Predicted membrane proteins" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 17.1;skin 1: 25.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 149.2;Colonocytes: 183.6;Endometrial glandular cells: 153.0;Goblet cells: 213.1;Ocular epithelial cells: 225.6;Pancreatic acinar cells: 182.8;Renal collecting duct principal cells: 153.7;Urothelial cells: 416.3" "Cell type enhanced" "Detected in many" "deep-layer near-projecting: 25.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Liver - Cholangiocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA008119, HPA011968" Uncertain NA NA "Cluster 60: Stomach - Digestion" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 69: Urothelial cells - Basic cellular functions" 104 "HPA008119: , HPA011968: " "unprognostic (5.19e-2)" "unprognostic (3.23e-2)" "unprognostic (8.32e-2)" "unprognostic (2.34e-2)" "unprognostic (6.00e-3)" "unprognostic (9.26e-2)" "unprognostic (4.77e-2)" "potential prognostic unfavorable (4.87e-5)" "unprognostic (6.44e-2)" "unprognostic (2.63e-2)" "unprognostic (1.03e-1)" "unprognostic (1.80e-1)" "unprognostic (1.01e-2)" "unprognostic (2.26e-1)" "unprognostic (2.51e-2)" "unprognostic (5.80e-3)" "unprognostic (3.83e-1)" "potential prognostic unfavorable (4.27e-4)" "unprognostic (1.36e-2)" "unprognostic (2.10e-2)" "unprognostic (1.50e-1)" "unprognostic (2.88e-3)" "unprognostic (3.63e-1)" "unprognostic (1.06e-1)" "unprognostic (1.86e-1)" "unprognostic (2.96e-3)" "unprognostic (7.83e-2)" C3orf56 FLJ40141 ENSG00000214324 "Chromosome 3 open reading frame 56" Q8N813 3 127193131-127198185 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Undifferentiated spermatogonia: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Spermatogonia" HPA055395 Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 6: Leukemia - Signal transduction" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 1 Nucleoplasm "Centrosome, Cytosol" "HPA055395: " C3orf62 "FLJ43654, MAPS" ENSG00000188315 "Chromosome 3 open reading frame 62" Q6ZUJ4 3 49268596-49277232 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 48.2;Late primary spermatocytes: 97.1;Neutrophils: 141.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 8 "neutrophil: 40.1" "Lineage enriched" "Detected in many" 8 "granulocytes: 40.1" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA043328, CAB080594" Approved Approved "Nuclear speckles" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 67: Testis - Mixed function" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 24: Neutrophils - Innate immunity signal integration" 14 "Nuclear speckles" "CAB080594: , HPA043328: " "unprognostic (2.62e-2)" "unprognostic (6.35e-2)" "unprognostic (1.37e-1)" "unprognostic (3.33e-1)" "unprognostic (2.76e-2)" "unprognostic (6.17e-2)" "unprognostic (8.26e-2)" "unprognostic (4.42e-2)" "unprognostic (5.45e-3)" "unprognostic (9.15e-3)" "unprognostic (5.30e-2)" "unprognostic (2.02e-1)" "unprognostic (2.73e-1)" "unprognostic (2.37e-3)" "unprognostic (4.61e-2)" "unprognostic (7.20e-3)" "unprognostic (3.03e-1)" "unprognostic (7.50e-2)" "unprognostic (1.91e-2)" "unprognostic (9.14e-2)" "unprognostic (1.24e-1)" "potential prognostic favorable (7.27e-5)" "unprognostic (9.05e-2)" "unprognostic (1.13e-1)" "unprognostic (1.88e-2)" "unprognostic (1.89e-2)" "unprognostic (3.72e-1)" "unprognostic (7.40e-3)" "unprognostic (1.68e-1)" "unprognostic (1.52e-2)" "unprognostic (2.64e-2)" C3orf70 ENSG00000187068 "Chromosome 3 open reading frame 70" A6NLC5 3 185076838-185153060 "Cancer-related genes, Predicted intracellular proteins" Neurogenesis "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 13.8" "Cell type enhanced" "Detected in many" "Astrocytes: 82.4;Bergmann glia: 102.9;Melanocytes: 57.2;Oligodendrocyte progenitor cells: 205.6;Peritubular myoid cells: 58.1;Retinal amacrine cells: 71.3;Retinal bipolar cells: 147.9;Sertoli cells: 80.6;Smooth muscle cells: 143.3;Tuft cells: 69.2;Vascular smooth muscle cells: 49.4" "Cell type enhanced" "Detected in all" "oligodendrocyte precursor cell: 245.7" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 13.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 3.0" "Adipose subcutaneous - Smooth muscle cells, Colon - Smooth muscle cells, Lung - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041861 Uncertain Approved Cytosol NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 1 Cytosol "HPA041861: " "unprognostic (2.80e-3)" "unprognostic (1.65e-1)" "unprognostic (1.04e-1)" "unprognostic (5.46e-3)" "unprognostic (3.06e-2)" "unprognostic (2.30e-1)" "unprognostic (9.62e-2)" "unprognostic (2.27e-1)" "validated prognostic favorable (3.82e-6)" "validated prognostic favorable (7.84e-4)" "unprognostic (2.45e-3)" "unprognostic (6.54e-3)" "unprognostic (4.37e-2)" "unprognostic (3.61e-2)" "unprognostic (9.67e-2)" "unprognostic (1.31e-1)" "unprognostic (2.67e-2)" "unprognostic (2.86e-2)" "unprognostic (2.21e-1)" "unprognostic (7.38e-2)" C3orf80 ENSG00000180044 "Chromosome 3 open reading frame 80" F5H4A9 3 160225422-160228213 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 12.5;esophagus: 4.3;intestine: 7.2" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 8.6;Esophageal apical cells: 46.1;Hematopoietic stem cells: 29.6;Late primary spermatocytes: 9.5;Megakaryocyte progenitors: 9.3;Megakaryocyte-Erythroid progenitors: 8.2;Megakaryocytes: 30.9;Neuroendocrine cells: 7.4;Parietal cells: 8.8;Retinal horizontal cells: 6.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 8.6" "Kidney - Fibroblasts, Pituitary gland - Lactotropes, Prostate - Fibroblasts, Spleen - Fibroblasts_1, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA047439 Uncertain NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 84: Apical squamous epithelium - Cornification" "HPA047439: " "unprognostic (5.61e-2)" "unprognostic (2.24e-2)" "unprognostic (1.87e-2)" "unprognostic (7.20e-3)" "unprognostic (1.36e-1)" "unprognostic (4.85e-3)" "unprognostic (4.04e-3)" "unprognostic (2.09e-2)" "unprognostic (9.73e-2)" "unprognostic (5.51e-2)" "unprognostic (1.15e-1)" "unprognostic (3.45e-3)" "unprognostic (9.09e-2)" "unprognostic (1.10e-2)" "unprognostic (8.52e-2)" "unprognostic (2.15e-1)" "unprognostic (1.33e-1)" "unprognostic (3.15e-2)" "unprognostic (8.34e-3)" "unprognostic (8.27e-3)" "unprognostic (6.63e-3)" C3orf84 ENSG00000236980 "Chromosome 3 open reading frame 84" H3BNL1 3 49177634-49191858 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 69 "testis: 6.9" "Group enriched" "Detected in some" 14 "Early spermatids: 153.9;Late primary spermatocytes: 100.8;Late spermatids: 137.5" "Low cell type specificity" "Detected in single" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 48: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" C3orf85 FLJ22763 ENSG00000241224 "Chromosome 3 open reading frame 85" A0A1B0GTC6 3 109118252-109151401 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 66.4;kidney: 13.0;liver: 18.5" "Cell type enriched" "Detected in some" 7 "Enterocytes: 940.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Colon Adenocarcinoma (TCGA): 2.6;Rectum Adenocarcinoma (TCGA): 3.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "colorectal cancer: 1.6" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA 2700000 "Cluster 77: Intestine - Digestion" "Cluster 9: Non-specific - Receptor signaling" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 1: Enterocytes - Absorption and Digestion" "unprognostic (6.37e-2)" "unprognostic (5.60e-2)" "unprognostic (1.91e-1)" "unprognostic (3.37e-3)" "unprognostic (1.02e-2)" "unprognostic (9.47e-3)" "unprognostic (2.55e-1)" C4A "C4, C4A2, C4A3, C4A4, C4A6, C4B, C4S, CO4, CPAMD2, RG" ENSG00000244731 "Complement C4A (Rodgers blood group)" P0C0L4 6 31982057-32002681 "Blood group antigen proteins, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement pathway, Immunity, Inflammatory response, Innate immunity" "Blood group antigen" "Disease variant, FDA approved drug targets, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 117.5;liver: 341.8" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Breast Invasive Carcinoma (TCGA): 55.1;Kidney Renal Clear Cell Carcinoma (TCGA): 49.6;Kidney Renal Papillary Cell Carcinoma (TCGA): 32.8;Liver Hepatocellular Carcinoma (TCGA): 90.9;Thyroid Carcinoma (TCGA): 27.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 8.8;Myeloma: 6.7" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "CAB009811, CAB032603, HPA046356, HPA048287, HPA050103" Supported "Secreted to blood" "Complement pathway" NA NA 342000000 230000000000 "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 39: Astrocytes - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 13 "CAB009811: , CAB032603: , HPA046356: , HPA048287: , HPA050103: " "unprognostic (3.29e-2)" "unprognostic (5.40e-2)" "unprognostic (2.30e-1)" "unprognostic (1.09e-2)" "unprognostic (1.84e-1)" "unprognostic (1.03e-2)" "unprognostic (1.97e-2)" "unprognostic (2.58e-1)" "unprognostic (9.96e-2)" "unprognostic (8.69e-2)" "unprognostic (7.36e-2)" "unprognostic (4.31e-2)" "unprognostic (1.90e-1)" "unprognostic (1.61e-3)" "unprognostic (1.64e-3)" "unprognostic (2.16e-2)" "unprognostic (2.03e-1)" "unprognostic (8.15e-3)" "unprognostic (4.88e-2)" "unprognostic (2.63e-2)" "unprognostic (3.99e-2)" "unprognostic (7.66e-2)" "unprognostic (5.83e-2)" "unprognostic (1.88e-1)" "unprognostic (3.94e-1)" "unprognostic (9.91e-2)" "unprognostic (7.39e-2)" "unprognostic (6.37e-2)" "unprognostic (6.46e-2)" C4B "C4B1, C4B3, C4F, CH, CO4, CPAMD3" ENSG00000224389 "Complement C4B (Chido blood group)" P0C0L5 6 32014795-32035418 "Blood group antigen proteins, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement pathway, Immunity, Inflammatory response, Innate immunity" "Blood group antigen" "FDA approved drug targets, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "adrenal gland: 174.9;liver: 262.1" "Cell type enhanced" "Detected in single" "Epicardial cells: 2.3" "Cell type enhanced" "Detected in some" "astrocyte: 1.4;vascular associated smooth muscle cell: 1.0" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 238.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 6.7;Myeloma: 3.9" "Adipose visceral - Mesothelial cells, Heart muscle - Macrophages, Liver - Hepatocytes" "HPA046356, HPA048287, HPA050103" Approved "Secreted to blood" "Complement pathway" NA NA 447000000000 230000000000 "Cluster 76: Non-specific - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 2 "HPA046356: , HPA048287: , HPA050103: " "unprognostic (7.64e-2)" "unprognostic (2.28e-1)" "unprognostic (4.09e-2)" "unprognostic (3.50e-2)" "unprognostic (2.70e-3)" "unprognostic (2.73e-1)" "unprognostic (1.85e-1)" "unprognostic (1.57e-2)" "unprognostic (4.36e-2)" "unprognostic (5.15e-2)" "unprognostic (1.25e-1)" "unprognostic (1.34e-1)" "unprognostic (7.96e-2)" "unprognostic (1.61e-3)" "unprognostic (8.48e-2)" "unprognostic (1.16e-3)" "unprognostic (1.30e-1)" "potential prognostic unfavorable (7.93e-4)" "unprognostic (2.86e-1)" "unprognostic (2.41e-3)" "unprognostic (2.31e-2)" "unprognostic (3.75e-1)" "unprognostic (2.25e-1)" "unprognostic (2.00e-1)" "unprognostic (6.92e-3)" "unprognostic (4.65e-2)" "unprognostic (1.53e-1)" "unprognostic (1.71e-1)" "unprognostic (1.75e-2)" "unprognostic (1.29e-1)" C4BPA C4BP ENSG00000123838 "Complement component 4 binding protein alpha" P04003 1 207104233-207144972 "Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "liver: 1793.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 195.9;Alveolar cells type 2: 396.9;Endometrial glandular cells: 94.7;Hepatocytes: 1056.8;Transitional alveolar cells: 240.3" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 18 "Liver Hepatocellular Carcinoma (TCGA): 630.3;Lung Adenocarcinoma (TCGA): 177.5" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 137 "neutrophil: 29.6" "Lineage enriched" "Detected in single" 137 "granulocytes: 29.6" "Cancer enhanced" "Detected in some" "liver cancer: 7.4;lung cancer: 3.9" "Liver - Hepatocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells" "Not detected" "Not detected" "Region enhanced" "Detected in single" "midbrain: 1.6" "HPA000926, HPA001578" Enhanced "Secreted to blood" "Complement pathway" NA NA 30800000000 40000000000 "Cluster 4: Neutrophils - Degranulation" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 5 "HPA000926: , HPA001578: " "unprognostic (2.11e-3)" "unprognostic (1.78e-1)" "unprognostic (7.92e-2)" "unprognostic (4.28e-2)" "unprognostic (2.98e-1)" "potential prognostic unfavorable (3.90e-6)" "unprognostic (7.08e-2)" "potential prognostic favorable (3.54e-4)" "unprognostic (1.95e-2)" "potential prognostic favorable (2.16e-5)" "unprognostic (2.87e-1)" "potential prognostic unfavorable (9.90e-4)" "unprognostic (2.68e-1)" "unprognostic (2.27e-1)" "unprognostic (2.62e-2)" "unprognostic (1.91e-2)" "unprognostic (1.17e-1)" "unprognostic (2.86e-1)" "unprognostic (1.41e-1)" "unprognostic (1.10e-2)" C4BPB C4BP ENSG00000123843 "Complement component 4 binding protein beta" P20851 1 207088860-207099993 "Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "liver: 440.2" "Cell type enriched" "Detected in many" 9 "Hepatocytes: 685.8" "Low cell type specificity" "Detected in single" "Cancer enriched" "Detected in many" 21 "Liver Hepatocellular Carcinoma (TCGA): 320.4" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.1" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Bile duct cancer: 39.5" "Adipose subcutaneous - Macrophages, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "HPA000925, HPA051620" Approved Uncertain "Golgi apparatus" "Secreted to blood" "Complement pathway" NA NA 265000000000 1900000000 "Cluster 30: Non-specific - DNA binding" "Cluster 53: Liver - Plasma proteins" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 1 "Golgi apparatus" "HPA000925: , HPA051620: " "unprognostic (1.08e-1)" "unprognostic (1.36e-1)" "unprognostic (1.15e-1)" "unprognostic (1.85e-1)" "unprognostic (3.37e-1)" "unprognostic (1.48e-1)" "unprognostic (2.67e-3)" "unprognostic (1.32e-2)" "unprognostic (4.88e-3)" "unprognostic (7.85e-2)" "unprognostic (2.46e-2)" "unprognostic (2.60e-2)" "unprognostic (3.84e-2)" "unprognostic (2.96e-1)" "unprognostic (2.29e-2)" "unprognostic (2.92e-1)" "unprognostic (3.22e-1)" C4orf17 DKFZP434G072 ENSG00000138813 "Chromosome 4 open reading frame 17" Q53FE4 4 99511012-99542303 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 188 "testis: 18.7" "Group enriched" "Detected in some" 26 "Early spermatids: 158.7;Late primary spermatocytes: 246.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA060374, HPA060564" Uncertain Approved "Mid piece" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 5 "Mid piece" "HPA060374: , HPA060564: " C4orf19 FLJ11017 ENSG00000154274 "Chromosome 4 open reading frame 19" Q8IY42 4 37453925-37623495 "Predicted intracellular proteins" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 33.6" "Cell type enhanced" "Detected in many" "Cholangiocytes: 325.2;Distal convoluted tubule cells: 385.3;Epicardial cells: 523.1;Renal connecting tubule cells: 422.0" "Cell type enhanced" "Detected in many" "Bergmann glia: 169.8;central nervous system macrophage: 145.0;choroid plexus epithelial cell: 134.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 8.4" "Lineage enriched" "Detected in many" 5 "granulocytes: 8.4" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Colon - Colon enterocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Skin - Eccrine sweat gland cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043458, HPA052894" Enhanced Approved "Nucleoplasm,Cell Junctions" No No "Cluster 21: Neutrophils - Unknown function" "Cluster 60: Stomach - Digestion" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 27: Breast cancer - Unknown function" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 8 Nucleoplasm "Cell Junctions" "HPA043458: , HPA052894: " "unprognostic (4.40e-2)" "unprognostic (2.37e-1)" "unprognostic (3.52e-1)" "unprognostic (1.29e-1)" "potential prognostic favorable (5.21e-4)" "unprognostic (2.59e-2)" "unprognostic (1.04e-1)" "unprognostic (1.68e-2)" "unprognostic (1.81e-3)" "unprognostic (2.89e-2)" "potential prognostic favorable (2.37e-9)" "unprognostic (1.25e-3)" "unprognostic (1.92e-1)" "unprognostic (3.43e-2)" "unprognostic (7.83e-2)" "unprognostic (2.26e-1)" "unprognostic (2.77e-2)" "unprognostic (5.53e-2)" "unprognostic (1.04e-1)" "unprognostic (1.34e-1)" "unprognostic (4.16e-2)" "unprognostic (5.54e-2)" "unprognostic (5.70e-2)" "potential prognostic unfavorable (6.30e-4)" "unprognostic (2.45e-2)" "unprognostic (6.49e-3)" "unprognostic (3.47e-2)" "unprognostic (9.53e-2)" "unprognostic (1.14e-1)" "unprognostic (1.19e-3)" "unprognostic (9.11e-2)" C4orf3 "ALN, HCVFTP1" ENSG00000164096 "Chromosome 4 open reading frame 3" Q8WVX3 4 119296419-119304445 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 9 "Esophageal apical cells: 17730.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026907 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 47: Endothelial cells - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 84: Apical squamous epithelium - Cornification" 14 "Endoplasmic reticulum" "HPA026907: " "unprognostic (1.11e-1)" "unprognostic (7.53e-2)" "unprognostic (6.49e-2)" "unprognostic (2.24e-2)" "unprognostic (3.68e-1)" "unprognostic (1.28e-1)" "unprognostic (9.58e-2)" "unprognostic (4.26e-3)" "unprognostic (9.76e-3)" "unprognostic (4.23e-3)" "validated prognostic favorable (1.67e-9)" "validated prognostic favorable (9.32e-4)" "unprognostic (2.44e-3)" "unprognostic (3.76e-2)" "unprognostic (7.63e-2)" "unprognostic (1.10e-1)" "potential prognostic unfavorable (8.15e-4)" "unprognostic (1.18e-1)" "unprognostic (2.12e-1)" "unprognostic (1.61e-1)" "unprognostic (1.58e-2)" "unprognostic (9.42e-2)" "unprognostic (1.05e-1)" "unprognostic (2.16e-1)" "unprognostic (9.23e-2)" "unprognostic (3.06e-1)" "unprognostic (4.64e-2)" "unprognostic (9.19e-3)" "unprognostic (2.72e-1)" "unprognostic (8.91e-2)" "unprognostic (1.31e-3)" C4orf33 FLJ33703 ENSG00000151470 "Chromosome 4 open reading frame 33" Q8N1A6 4 129093317-129116640 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epicardial cells: 91.0;Megakaryocytes: 86.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061199 Uncertain Approved "Nuclear bodies,Golgi apparatus" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 25: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 103: Non-specific - Basic cellular processes" 6 "Golgi apparatus" "Nuclear bodies" "HPA061199: " "unprognostic (1.18e-2)" "unprognostic (2.12e-1)" "unprognostic (4.59e-1)" "unprognostic (5.15e-3)" "unprognostic (8.22e-2)" "unprognostic (9.40e-3)" "unprognostic (3.76e-1)" "unprognostic (3.96e-2)" "unprognostic (1.27e-2)" "unprognostic (9.23e-3)" "potential prognostic favorable (2.23e-7)" "unprognostic (1.10e-2)" "potential prognostic favorable (5.46e-4)" "unprognostic (2.24e-2)" "unprognostic (1.15e-1)" "unprognostic (1.14e-1)" "unprognostic (5.46e-2)" "unprognostic (2.35e-2)" "unprognostic (1.25e-1)" "unprognostic (3.81e-1)" "unprognostic (4.89e-2)" "unprognostic (1.13e-2)" "unprognostic (4.90e-2)" "unprognostic (8.03e-2)" "unprognostic (1.42e-3)" "unprognostic (5.93e-2)" "unprognostic (9.72e-3)" "unprognostic (1.64e-1)" "unprognostic (2.15e-1)" "unprognostic (2.07e-2)" "unprognostic (1.69e-1)" C4orf36 MGC26744 ENSG00000163633 "Chromosome 4 open reading frame 36" Q96KX1 4 86876205-86892422 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 7 "testis: 9.8" "Group enriched" "Detected in many" 17 "Early spermatids: 69.4;Late spermatids: 123.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 4.9" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA057434 Uncertain Approved "Vesicles,Focal adhesion sites,Cytosol" NA NA "Cluster 47: Testis - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" "Focal adhesion sites, Cytosol" Vesicles "HPA057434: " "unprognostic (1.62e-2)" "unprognostic (1.19e-2)" "unprognostic (2.16e-1)" "unprognostic (2.58e-1)" "unprognostic (9.54e-3)" C4orf45 FLJ25371 ENSG00000164123 "Chromosome 4 open reading frame 45" Q96LM5 4 158893134-159038760 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 18 "testis: 9.9" "Group enriched" "Detected in many" 5 "Cardiomyocytes: 257.9;Early spermatids: 424.0;Late primary spermatocytes: 349.5;Late spermatids: 124.7" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA077313 Approved "Mid piece,Principal piece" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 53: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 16 "Mid piece, Principal piece" "HPA077313: " C4orf46 "LOC201725, RCDG1" ENSG00000205208 "Chromosome 4 open reading frame 46" Q504U0 4 158666675-158672255 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 43.9;Late primary spermatocytes: 59.7;Melanocytes: 30.7;Rod photoreceptor cells: 34.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047287 Uncertain Supported Cytosol NA NA "Cluster 1: T-cells - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 14 Cytosol "HPA047287: " "unprognostic (3.19e-1)" "unprognostic (2.96e-1)" "unprognostic (7.97e-2)" "unprognostic (9.01e-2)" "unprognostic (4.86e-2)" "unprognostic (9.35e-2)" "unprognostic (7.80e-2)" "unprognostic (4.56e-1)" "unprognostic (2.71e-2)" "unprognostic (2.09e-2)" "potential prognostic favorable (3.18e-4)" "unprognostic (3.63e-1)" "unprognostic (1.10e-1)" "potential prognostic unfavorable (2.51e-5)" "unprognostic (2.16e-3)" "unprognostic (7.37e-2)" "potential prognostic unfavorable (4.72e-4)" "unprognostic (8.70e-2)" "unprognostic (1.56e-1)" "unprognostic (2.75e-2)" "unprognostic (1.02e-2)" "unprognostic (5.66e-2)" "unprognostic (1.65e-1)" "unprognostic (4.77e-2)" "unprognostic (2.13e-2)" "unprognostic (1.74e-2)" "unprognostic (1.48e-2)" "unprognostic (3.45e-2)" "unprognostic (1.61e-1)" "unprognostic (9.18e-3)" "unprognostic (3.61e-1)" C4orf47 LOC441054 ENSG00000205129 "Chromosome 4 open reading frame 47" A7E2U8 4 185426249-185449826 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "choroid plexus: 29.9;fallopian tube: 11.0;retina: 12.5;testis: 10.9" "Group enriched" "Detected in many" 4 "Choroid plexus epithelial cells: 309.7;Cone photoreceptor cells: 138.7;Early spermatids: 194.1;Endometrial ciliated cells: 227.3;Ependymal cells: 545.8;Epididymal efferent duct ciliated cells: 526.3;Fallopian tube ciliated cells: 417.8;Late primary spermatocytes: 261.3;Oocytes: 170.4;Respiratory ciliated cells: 511.9;Rod photoreceptor cells: 226.8" "Group enriched" "Detected in all" 5 "choroid plexus epithelial cell: 384.3;ependymal cell: 668.6" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 6.9" "Region enhanced" "Detected in all" "choroid plexus: 48.2" "Immune cell enhanced" "Detected in single" "neutrophil: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA063485 Enhanced Approved "Principal piece,End piece" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 15: Kidney cancer - Membrane components" "Cluster 34: Ciliated cells - Cilia assembly & function" 1 "Principal piece, End piece" "HPA063485: " "unprognostic (4.18e-2)" "unprognostic (1.64e-1)" "unprognostic (6.21e-2)" "unprognostic (1.49e-2)" "unprognostic (1.99e-2)" "unprognostic (5.42e-2)" "unprognostic (5.68e-2)" "unprognostic (4.52e-3)" "unprognostic (2.63e-1)" "unprognostic (4.08e-3)" "unprognostic (2.44e-1)" "unprognostic (2.48e-1)" "unprognostic (2.56e-1)" "unprognostic (1.01e-1)" "unprognostic (2.76e-1)" "potential prognostic unfavorable (7.12e-4)" "unprognostic (8.31e-2)" "unprognostic (1.96e-2)" "unprognostic (2.23e-1)" C4orf48 ENSG00000243449 "Chromosome 4 open reading frame 48" Q5BLP8 4 2041995-2043964 "Predicted secreted proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 149.7;pituitary gland: 72.7" "Cell type enhanced" "Detected in many" "Colonocytes: 379.4;Epididymal efferent duct ciliated cells: 599.8;Fallopian tube ciliated cells: 366.4;Granulosa cells: 630.1;Hofbauer cells: 358.6;Late spermatids: 575.9;Melanocytes: 483.2;Pancreatic islet cells: 404.3;Parietal cells: 553.4" "Cell type enhanced" "Detected in all" "oligodendrocyte: 278.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052447 Uncertain Approved Cytosol "Secreted to blood" Other NA NA 675000 110000 "Cluster 29: Non-specific - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 27: Non-specific - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" Cytosol "HPA052447: " "unprognostic (2.25e-1)" "unprognostic (8.33e-2)" "unprognostic (2.09e-1)" "unprognostic (1.81e-2)" "unprognostic (2.17e-1)" "unprognostic (3.55e-3)" "unprognostic (1.03e-1)" "unprognostic (2.53e-1)" "unprognostic (3.58e-2)" "unprognostic (3.59e-2)" "potential prognostic unfavorable (1.08e-6)" "unprognostic (7.56e-3)" "unprognostic (8.75e-2)" "unprognostic (1.14e-3)" "unprognostic (1.62e-1)" "unprognostic (3.12e-3)" "unprognostic (4.92e-2)" "unprognostic (3.47e-2)" "unprognostic (1.11e-1)" "unprognostic (1.44e-1)" "unprognostic (2.81e-2)" "unprognostic (2.06e-2)" "unprognostic (3.55e-2)" "unprognostic (2.64e-1)" "unprognostic (1.26e-1)" "unprognostic (7.14e-2)" "unprognostic (4.53e-3)" "unprognostic (1.24e-1)" "unprognostic (1.58e-1)" "unprognostic (9.77e-2)" C4orf50 FLJ46481 ENSG00000181215 "Chromosome 4 open reading frame 50" 4 5897373-6200555 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 21.3;Brain excitatory neurons: 43.1;Brain inhibitory neurons: 62.5;Müller glia: 19.2;Oocytes: 18.4;Other brain neurons: 36.3;Retinal ganglion cells: 46.4" "Cell type enhanced" "Detected in many" "medium spiny neuron: 155.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 33: Neurons - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" "unprognostic (2.72e-1)" C4orf51 ENSG00000237136 "Chromosome 4 open reading frame 51" C9J302 4 145680146-145771032 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 14 "testis: 5.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 71.4;Early spermatids: 109.1;Epicardial cells: 34.1;Late primary spermatocytes: 80.1" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in some" 5 "Kidney Chromophobe (TCGA): 1.3;Testicular Germ Cell Tumor (TCGA): 2.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 27: Breast cancer - Unknown function" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" "unprognostic (6.94e-2)" "unprognostic (2.22e-1)" C4orf54 "FOPV, LOC285556" ENSG00000248713 "Chromosome 4 open reading frame 54" D6RIA3 4 99636529-99657828 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "skeletal muscle: 65.7" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 7.5;Endometrial ciliated cells: 21.8;Epididymal efferent duct ciliated cells: 12.6;Fallopian tube ciliated cells: 4.9;Myonuclei: 53.6;Renal collecting duct principal cells: 7.9;Thymic myoid cells: 17.7" "Group enriched" "Detected in some" 4 "eccentric medium spiny neuron: 4.9;medium spiny neuron: 10.1" "Not detected" "Not detected" "Region enhanced" "Detected in some" "basal ganglia: 2.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lymphoma: 1.0" "Kidney - Ascending Loop of Henle cells, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" HPA079091 Approved "Nuclear bodies,Cytosol" NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 53: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 46: Skeletal myocytes - Muscle structure & formation" "Nuclear bodies" Cytosol "HPA079091: " C5 "C5a, C5b, CPAMD4" ENSG00000106804 "Complement C5" P01031 9 120932987-121075195 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement alternate pathway, Complement pathway, Cytolysis, Immunity, Inflammatory response, Innate immunity" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 30 "liver: 418.8" "Cell type enriched" "Detected in many" 13 "Hepatocytes: 861.1" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 9 "Liver Hepatocellular Carcinoma (TCGA): 102.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "liver cancer: 21.1" "Liver - Hepatocytes" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA029339 Supported "Secreted to blood" "Complement pathway" NA NA 113000000000 43000000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 46: Brainstem - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 22 "HPA029339: " "unprognostic (3.43e-1)" "unprognostic (1.10e-1)" "potential prognostic favorable (8.56e-4)" "unprognostic (9.85e-3)" "potential prognostic unfavorable (1.70e-4)" "unprognostic (1.01e-1)" "unprognostic (2.40e-1)" "unprognostic (9.54e-3)" "unprognostic (1.75e-1)" "unprognostic (7.55e-2)" "unprognostic (1.60e-3)" "unprognostic (5.49e-3)" "unprognostic (1.16e-3)" "unprognostic (2.48e-1)" "unprognostic (6.56e-2)" "unprognostic (2.76e-2)" "unprognostic (3.72e-1)" "unprognostic (1.08e-1)" "unprognostic (5.01e-2)" "unprognostic (2.04e-1)" "unprognostic (7.20e-2)" "unprognostic (1.99e-1)" "unprognostic (2.19e-1)" "unprognostic (5.09e-2)" "unprognostic (8.39e-2)" "unprognostic (2.29e-1)" "unprognostic (1.09e-1)" C5AR1 "C5A, C5AR, C5R1, CD88" ENSG00000197405 "Complement C5a receptor 1" P21730 19 47290023-47322066 "CD markers, FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 118.4;lymphoid tissue: 80.0" "Group enriched" "Detected in many" 4 "monocytes: 1285.2;Neutrophils: 2460.4" "Group enriched" "Detected in many" 5 "choroid plexus epithelial cell: 147.9;ependymal cell: 192.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 393.7" "Group enriched" "Detected in many" 42 "granulocytes: 393.7;monocytes: 116.2" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Neutrophils, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Neutrophils, Minor Salivary Gland - Macrophages" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB002720, HPA014520, HPA048012" Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 41 "Golgi apparatus" Vesicles "CAB002720: , HPA014520: , HPA048012: " "unprognostic (2.00e-2)" "unprognostic (7.55e-2)" "unprognostic (1.29e-1)" "unprognostic (2.13e-2)" "unprognostic (9.67e-2)" "unprognostic (1.62e-1)" "unprognostic (3.64e-2)" "unprognostic (2.08e-3)" "unprognostic (5.45e-2)" "unprognostic (7.28e-2)" "unprognostic (2.59e-1)" "unprognostic (2.23e-1)" "unprognostic (1.00e-1)" "unprognostic (8.75e-3)" "unprognostic (5.35e-2)" "unprognostic (7.23e-2)" "unprognostic (4.86e-2)" "unprognostic (3.15e-2)" "unprognostic (1.30e-1)" "potential prognostic unfavorable (3.62e-4)" "unprognostic (3.49e-2)" "unprognostic (2.80e-1)" "unprognostic (3.72e-2)" "unprognostic (9.68e-2)" "unprognostic (2.96e-2)" "unprognostic (1.05e-2)" "unprognostic (9.83e-3)" "unprognostic (6.92e-3)" "unprognostic (5.28e-2)" "unprognostic (5.03e-2)" "unprognostic (4.42e-2)" C5AR2 "C5L2, GPR77" ENSG00000134830 "Complement C5a receptor 2" Q9P296 19 47332175-47347329 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 13.2" "Cell type enhanced" "Detected in some" "cDC: 35.4;Kupffer cells: 149.6;Macrophages: 84.4;monocytes: 139.2;Neutrophil progenitors: 56.3;Neutrophils: 240.8" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 20.0;deep-layer corticothalamic and 6b: 13.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 17.8;eosinophil: 11.9;neutrophil: 33.1" "Lineage enriched" "Detected in many" 7 "granulocytes: 33.1" "Cancer enhanced" "Detected in some" "breast cancer: 5.6;Leukemia: 3.4" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Minor Salivary Gland - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA016629 Uncertain NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 1 "HPA016629: " "unprognostic (2.85e-1)" "unprognostic (1.47e-1)" "unprognostic (1.72e-1)" "unprognostic (1.47e-1)" "unprognostic (8.12e-2)" "unprognostic (2.79e-1)" "unprognostic (1.18e-2)" "unprognostic (1.18e-1)" "potential prognostic favorable (2.48e-4)" "unprognostic (2.57e-2)" "unprognostic (1.67e-2)" "unprognostic (2.38e-3)" "unprognostic (1.49e-2)" "unprognostic (1.18e-1)" "unprognostic (2.77e-2)" "unprognostic (1.31e-1)" "unprognostic (1.55e-2)" "potential prognostic unfavorable (3.24e-4)" "unprognostic (2.68e-3)" "unprognostic (4.82e-2)" "unprognostic (2.11e-1)" "unprognostic (2.75e-1)" "unprognostic (1.70e-2)" "unprognostic (2.30e-3)" C5orf15 "HTGN29, KCT2" ENSG00000113583 "Chromosome 5 open reading frame 15" Q8NC54 5 133955510-133968674 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fallopian tube ciliated cells: 149.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011951, HPA039165" Uncertain Approved "Golgi apparatus" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 108: Fibroblasts - ECM organization" 3 "Golgi apparatus" "HPA011951: , HPA039165: " "unprognostic (1.74e-2)" "unprognostic (2.19e-1)" "unprognostic (1.20e-2)" "unprognostic (2.25e-1)" "unprognostic (2.32e-2)" "unprognostic (5.24e-2)" "unprognostic (9.30e-2)" "potential prognostic unfavorable (1.43e-4)" "unprognostic (3.25e-3)" "unprognostic (2.76e-3)" "potential prognostic favorable (1.03e-4)" "unprognostic (1.59e-1)" "unprognostic (2.24e-2)" "unprognostic (5.76e-3)" "unprognostic (4.07e-1)" "unprognostic (4.71e-3)" "unprognostic (2.87e-2)" "unprognostic (1.53e-1)" "unprognostic (7.86e-3)" "unprognostic (1.97e-2)" "potential prognostic unfavorable (5.67e-4)" "unprognostic (3.23e-2)" "unprognostic (1.07e-3)" "unprognostic (3.65e-2)" "unprognostic (2.76e-1)" "unprognostic (3.04e-1)" "unprognostic (1.28e-2)" "unprognostic (4.14e-2)" "unprognostic (5.35e-2)" "unprognostic (8.84e-2)" "unprognostic (1.05e-1)" C5orf22 FLJ11193 ENSG00000082213 "Chromosome 5 open reading frame 22" Q49AR2 5 31532287-31555053 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Mast cells: 60.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 27.9" "Lineage enriched" "Detected in all" 5 "granulocytes: 27.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043062 Approved Approved "Nuclear membrane" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 29: Non-specific - Unknown function" "Cluster 58: Mast cells - Allergic inflammatory responses" 8 "Nuclear membrane" "HPA043062: " "unprognostic (6.80e-2)" "unprognostic (1.59e-2)" "unprognostic (2.69e-2)" "unprognostic (1.50e-2)" "unprognostic (7.86e-2)" "unprognostic (1.47e-1)" "unprognostic (2.86e-1)" "unprognostic (1.44e-1)" "unprognostic (1.22e-1)" "potential prognostic unfavorable (6.63e-4)" "potential prognostic favorable (1.58e-6)" "unprognostic (6.27e-2)" "unprognostic (1.33e-1)" "unprognostic (2.39e-2)" "unprognostic (2.58e-2)" "unprognostic (2.62e-1)" "unprognostic (4.09e-3)" "unprognostic (1.46e-1)" "unprognostic (3.06e-1)" "unprognostic (1.82e-1)" "unprognostic (2.00e-1)" "validated prognostic unfavorable (3.26e-4)" "validated prognostic unfavorable (3.44e-5)" "unprognostic (2.34e-1)" "unprognostic (3.10e-2)" "unprognostic (5.76e-2)" "unprognostic (8.11e-2)" "unprognostic (1.72e-1)" "unprognostic (5.19e-1)" "unprognostic (2.04e-3)" "unprognostic (9.59e-2)" C5orf24 FLJ37562 ENSG00000181904 "Chromosome 5 open reading frame 24" Q7Z6I8 5 134845680-134859735 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057749, HPA062502" Approved Supported Nucleoplasm NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 31: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 62: Smooth muscle cells - Muscle contraction" 5 Nucleoplasm "HPA057749: , HPA062502: " "unprognostic (3.48e-2)" "unprognostic (5.72e-2)" "unprognostic (2.00e-3)" "unprognostic (6.65e-2)" "unprognostic (2.54e-1)" "unprognostic (1.37e-1)" "unprognostic (8.23e-2)" "unprognostic (5.48e-2)" "unprognostic (1.76e-1)" "potential prognostic unfavorable (5.22e-4)" "potential prognostic favorable (2.75e-6)" "unprognostic (1.98e-2)" "unprognostic (9.68e-2)" "unprognostic (5.53e-2)" "unprognostic (3.31e-1)" "unprognostic (1.54e-1)" "unprognostic (1.81e-1)" "unprognostic (3.84e-1)" "unprognostic (8.51e-2)" "unprognostic (2.90e-1)" "potential prognostic unfavorable (6.50e-4)" "unprognostic (3.10e-2)" "unprognostic (4.89e-2)" "unprognostic (2.15e-2)" "unprognostic (5.53e-2)" "unprognostic (1.15e-2)" "unprognostic (7.76e-3)" "unprognostic (5.66e-2)" "unprognostic (1.52e-1)" "unprognostic (2.97e-2)" "unprognostic (1.40e-1)" C5orf34 FLJ32363 ENSG00000172244 "Chromosome 5 open reading frame 34" Q96MH7 5 43486709-43515148 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 35.0;Early primary spermatocytes: 32.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 2.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045386 Approved NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 53: Neurons - Mixed function" "Cluster 29: Non-specific - Unknown function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 3 "HPA045386: " "unprognostic (1.94e-2)" "unprognostic (1.01e-2)" "unprognostic (2.59e-1)" "unprognostic (9.09e-2)" "unprognostic (6.05e-2)" "unprognostic (1.43e-1)" "unprognostic (1.36e-1)" "unprognostic (1.19e-2)" "unprognostic (9.08e-3)" "unprognostic (1.34e-3)" "potential prognostic unfavorable (6.16e-4)" "unprognostic (3.84e-3)" "potential prognostic unfavorable (1.31e-4)" "unprognostic (3.24e-3)" "potential prognostic unfavorable (7.19e-4)" "unprognostic (2.58e-1)" "unprognostic (2.46e-2)" "unprognostic (1.91e-1)" "unprognostic (2.97e-1)" "unprognostic (4.82e-3)" "potential prognostic unfavorable (7.76e-4)" "unprognostic (3.83e-1)" "unprognostic (1.98e-1)" "unprognostic (6.44e-2)" "unprognostic (1.01e-1)" "unprognostic (1.48e-1)" "unprognostic (2.58e-3)" C5orf46 "AP-64, MGC23985, SSSP1" ENSG00000178776 "Chromosome 5 open reading frame 46" Q6UWT4 5 147880726-147906538 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "blood vessel: 85.7;salivary gland: 170.7;skin 1: 112.2" "Cell type enhanced" "Detected in some" "Breast secretory cells: 43.9;Cardiomyocytes: 43.9;Early spermatids: 428.5;Lacrimal acinar cells: 69.7;Late primary spermatocytes: 88.2;Late spermatids: 235.9;Salivary acinar cells: 332.9;Salivary myoepithelial cells: 174.8" "Group enriched" "Detected in some" 11 "choroid plexus epithelial cell: 5.4;upper rhombic lip: 4.5" "Cancer enriched" "Detected in many" 4 "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 216.0" "Group enriched" "Detected in some" 7 "cerebellum: 4.8;choroid plexus: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 61.6" "Heart muscle - Cardiomyocytes, Minor Salivary Gland - Minor salivary glandular cells, Skin - Keratinocyte (granular), Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA058999, HPA079692" Supported Approved "Nuclear speckles,Mitochondria" "Secreted in other tissues" "No annotated function" NA NA 180000 "Cluster 58: Skin - Keratinization" "Cluster 35: Non-specific - DNA binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 12 "Nuclear speckles" Mitochondria "HPA058999: , HPA079692: " "unprognostic (1.07e-1)" "unprognostic (1.89e-1)" "unprognostic (4.09e-3)" "unprognostic (2.25e-1)" "unprognostic (1.85e-3)" "unprognostic (5.08e-2)" "potential prognostic unfavorable (7.03e-4)" "unprognostic (2.44e-2)" "unprognostic (3.84e-3)" "unprognostic (3.00e-3)" "unprognostic (1.08e-1)" "unprognostic (8.06e-3)" "unprognostic (1.56e-1)" "unprognostic (1.85e-3)" "unprognostic (9.97e-2)" "unprognostic (4.43e-2)" "unprognostic (4.52e-3)" "unprognostic (8.08e-3)" "potential prognostic unfavorable (2.96e-4)" "potential prognostic unfavorable (2.50e-4)" "unprognostic (2.96e-2)" "unprognostic (1.00e-1)" "unprognostic (1.11e-1)" "unprognostic (1.27e-2)" "unprognostic (2.20e-1)" "unprognostic (1.05e-2)" "unprognostic (7.61e-2)" "unprognostic (7.28e-3)" C5orf47 LOC133491 ENSG00000185056 "Chromosome 5 open reading frame 47" Q569G3 5 173973779-174006140 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 98 "testis: 20.2" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 102.2;Early primary spermatocytes: 574.9;Early spermatids: 99.9;Late primary spermatocytes: 214.0;Undifferentiated spermatogonia: 37.2" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 70: DU4475 - Unknown function" "Cluster 3: Early primary spermatocytes - Early meiosis" C5orf49 LOC134121 ENSG00000215217 "Chromosome 5 open reading frame 49" A4QMS7 5 7830378-7851151 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 21.2;choroid plexus: 70.4;fallopian tube: 71.2;testis: 36.6" "Group enriched" "Detected in many" 4 "Early spermatids: 797.7;Endometrial ciliated cells: 373.2;Epididymal efferent duct ciliated cells: 515.0;Fallopian tube ciliated cells: 938.4;Late primary spermatocytes: 470.8;Late spermatids: 527.2;Respiratory ciliated cells: 770.6" "Cell type enriched" "Detected in many" 5 "ependymal cell: 214.0" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 21.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Bile duct cancer: 1.8" "Adrenal gland - Adrenal medulla cells, Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043759 Enhanced NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" 4 "HPA043759: " "unprognostic (1.69e-1)" "unprognostic (1.74e-1)" "unprognostic (5.27e-3)" "validated prognostic unfavorable (7.51e-5)" "validated prognostic unfavorable (3.80e-4)" "unprognostic (7.89e-2)" "unprognostic (2.33e-2)" "unprognostic (1.20e-1)" "potential prognostic favorable (4.74e-4)" "unprognostic (2.89e-1)" "unprognostic (6.61e-2)" "unprognostic (9.72e-2)" "unprognostic (4.52e-1)" "unprognostic (1.39e-1)" "unprognostic (1.56e-1)" "unprognostic (1.59e-1)" "unprognostic (1.53e-2)" "potential prognostic favorable (4.50e-4)" "unprognostic (1.49e-1)" "unprognostic (8.79e-2)" "unprognostic (1.26e-2)" "unprognostic (1.25e-2)" C5orf52 ENSG00000187658 "Chromosome 5 open reading frame 52" A6NGY3 5 157671533-157680158 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "testis: 35.6" "Cell type enriched" "Detected in some" 7 "Late spermatids: 3320.5" "Cell type enhanced" "Detected in single" "hippocampal CA4: 1.7" "Cancer enhanced" "Detected in some" "Colon Adenocarcinoma (TCGA): 2.4;Rectum Adenocarcinoma (TCGA): 2.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" "unprognostic (3.38e-2)" "potential prognostic favorable (4.63e-4)" "unprognostic (4.52e-2)" "unprognostic (2.64e-2)" C5orf58 ENSG00000234511 "Chromosome 5 open reading frame 58" C9J3I9 5 170229104-170252575 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 31 "testis: 201.0" "Group enriched" "Detected in some" 9 "Early primary spermatocytes: 1120.6;Late primary spermatocytes: 1046.9;Oocytes: 308.5" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 2.7;fibroblast: 2.7;leukocyte: 2.4" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 9.7" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Myeloma: 8.1" "Kidney - T-cells, Lung - NK-cells (Lung), Minor Salivary Gland - Macrophages, Stomach - Fibroblasts, Testis - Early spermatids, Thyroid gland - T-cells" "Low region specificity" "Detected in some" HPA052795 Approved "Cytokinetic bridge,Centriolar satellite,Cytosol" Yes NA "Cluster 24: Non-specific - Transcription" "Cluster 57: Testis - Spermatogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" "Centriolar satellite" "Cytokinetic bridge, Cytosol" "HPA052795: " "unprognostic (1.17e-2)" "unprognostic (7.51e-2)" "unprognostic (5.59e-2)" "unprognostic (1.22e-1)" "potential prognostic unfavorable (1.08e-5)" "unprognostic (1.68e-1)" "unprognostic (9.90e-2)" "unprognostic (8.43e-3)" "unprognostic (3.13e-2)" "unprognostic (1.14e-2)" "unprognostic (2.26e-3)" "unprognostic (1.40e-1)" "unprognostic (1.35e-1)" C5orf63 "FLJ44606, YDR286C" ENSG00000164241 "Chromosome 5 open reading frame 63" A6NC05 5 127045235-127073506 "Predicted intracellular proteins" "Electron transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 51.9;Late primary spermatocytes: 53.6;Sertoli cells: 58.0;Tuft cells: 69.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043240 Approved Approved Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 42: Retina - Visual perception" "Cluster 44: Non-specific - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 7: Non-specific - Transcription" Mitochondria "HPA043240: " "unprognostic (1.31e-1)" "unprognostic (1.46e-1)" "unprognostic (2.47e-2)" "unprognostic (3.96e-1)" "unprognostic (2.81e-2)" "unprognostic (2.13e-1)" "unprognostic (6.57e-2)" "unprognostic (4.23e-2)" "unprognostic (4.31e-2)" "unprognostic (7.30e-2)" "unprognostic (1.43e-1)" "potential prognostic favorable (5.07e-4)" "potential prognostic unfavorable (7.93e-4)" "unprognostic (4.73e-1)" "unprognostic (1.65e-1)" "unprognostic (1.04e-1)" "unprognostic (2.37e-1)" "unprognostic (2.48e-1)" "unprognostic (5.32e-2)" "unprognostic (1.07e-1)" "unprognostic (7.85e-3)" "unprognostic (1.47e-2)" "unprognostic (3.23e-1)" "unprognostic (6.32e-2)" "unprognostic (1.01e-1)" "unprognostic (1.64e-2)" "unprognostic (1.85e-2)" "unprognostic (1.21e-1)" "unprognostic (1.51e-2)" "unprognostic (2.42e-1)" C6 ENSG00000039537 "Complement C6" P13671 5 41142116-41261438 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" "Complement pathway, Cytolysis, Immunity, Innate immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "liver: 588.3" "Cell type enhanced" "Detected in many" "Adipocytes: 138.5;Cardiomyocytes: 76.3;Cholangiocytes: 334.6;Endometrial ciliated cells: 75.1;Epididymal efferent duct ciliated cells: 128.0;Fallopian tube ciliated cells: 335.2;Hepatocytes: 581.8;Late spermatids: 96.3;Leydig cells: 186.4;Pancreatic duct cells: 232.1;Respiratory ciliated cells: 205.7" "Cell type enhanced" "Detected in many" "ependymal cell: 19.6" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 78.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Bone cancer: 1.1" "Adrenal gland - Fibroblasts, Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Minor Salivary Gland - Adipocytes (Minor salivary gland), Pancreas - Macrophages, Spleen - Fibroblasts_2" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA043823, CAB069427" Enhanced "Secreted to blood" "Complement pathway" NA NA 45000000000 17000000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 3: Choroid plexus - Cilium" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 3 "CAB069427: , HPA043823: " "unprognostic (1.62e-2)" "unprognostic (1.18e-1)" "unprognostic (1.61e-3)" "unprognostic (3.95e-1)" "unprognostic (1.03e-1)" "unprognostic (3.82e-3)" "potential prognostic favorable (8.77e-6)" "unprognostic (5.59e-3)" "unprognostic (1.18e-2)" "unprognostic (1.68e-1)" "unprognostic (4.27e-3)" "potential prognostic unfavorable (6.61e-4)" "unprognostic (4.96e-1)" C6orf118 "bA85G2.1, MGC23884" ENSG00000112539 "Chromosome 6 open reading frame 118" Q5T5N4 6 165279664-165309605 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "choroid plexus: 9.4;fallopian tube: 15.4;testis: 6.6" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 130.9;Early spermatids: 120.2;Endometrial ciliated cells: 195.1;Ependymal cells: 333.5;Epididymal efferent duct ciliated cells: 237.1;Fallopian tube ciliated cells: 313.9;Late primary spermatocytes: 119.0;Late spermatids: 80.6;Respiratory ciliated cells: 333.0" "Group enriched" "Detected in many" 5 "choroid plexus epithelial cell: 135.4;ependymal cell: 360.2" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 3.5" "Region enhanced" "Detected in all" "choroid plexus: 62.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Pituitary gland - Somatotropes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "HPA029787, HPA029789" Approved Uncertain Mitochondria NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" Mitochondria "HPA029787: , HPA029789: " "unprognostic (7.76e-2)" "unprognostic (6.08e-2)" "unprognostic (2.15e-3)" "unprognostic (1.52e-2)" "unprognostic (1.70e-1)" C6orf120 bA160E12.4 ENSG00000185127 "Chromosome 6 open reading frame 120" Q7Z4R8 6 169702126-169706360 "Predicted secreted proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 123.6;Epicardial cells: 104.6;Late primary spermatocytes: 81.2;Late spermatids: 464.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039626 Uncertain "Secreted to blood" Other NA NA 960000 "Cluster 7: Non-specific - Innate immune response" "Cluster 76: Non-specific - Metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 4 "HPA039626: " "unprognostic (5.30e-2)" "unprognostic (7.08e-3)" "unprognostic (2.93e-1)" "unprognostic (3.18e-3)" "unprognostic (2.45e-1)" "potential prognostic favorable (9.64e-4)" "unprognostic (1.34e-1)" "unprognostic (2.98e-3)" "unprognostic (5.55e-3)" "unprognostic (6.22e-2)" "potential prognostic favorable (6.71e-5)" "unprognostic (5.09e-2)" "unprognostic (3.07e-1)" "potential prognostic unfavorable (9.20e-5)" "unprognostic (1.86e-3)" "unprognostic (9.61e-2)" "unprognostic (2.12e-1)" "unprognostic (8.43e-2)" "unprognostic (4.37e-3)" "unprognostic (1.05e-3)" "unprognostic (1.60e-1)" "unprognostic (1.19e-1)" "unprognostic (1.54e-1)" "unprognostic (2.99e-1)" "potential prognostic favorable (2.04e-4)" "unprognostic (1.98e-1)" "unprognostic (1.19e-1)" "unprognostic (3.65e-3)" "unprognostic (1.49e-1)" "unprognostic (1.26e-1)" "unprognostic (3.00e-1)" C6orf132 bA7K24.2 ENSG00000188112 "Chromosome 6 open reading frame 132" Q5T0Z8 6 42092233-42142620 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 142.8;skin 1: 65.5" "Cell type enriched" "Detected in many" 4 "Esophageal apical cells: 2336.8" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 95.2" "Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Liver - Cholangiocytes, Stomach - Gastric mucous cells, Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA044588 Enhanced Approved "Golgi apparatus,Cytosol" NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 51: Neurons - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 1 "Golgi apparatus, Cytosol" "HPA044588: " "unprognostic (3.48e-3)" "unprognostic (1.97e-1)" "unprognostic (1.66e-1)" "unprognostic (8.50e-2)" "unprognostic (3.14e-1)" "unprognostic (2.37e-2)" "unprognostic (1.85e-3)" "unprognostic (1.88e-1)" "unprognostic (4.96e-2)" "unprognostic (1.48e-1)" "unprognostic (1.61e-2)" "unprognostic (6.06e-2)" "unprognostic (1.94e-1)" "unprognostic (5.14e-2)" "unprognostic (5.80e-2)" "unprognostic (2.03e-2)" "unprognostic (2.81e-1)" "unprognostic (2.92e-2)" "unprognostic (5.77e-3)" "unprognostic (6.20e-2)" "unprognostic (6.57e-2)" "potential prognostic favorable (3.02e-4)" "unprognostic (1.50e-1)" "unprognostic (4.00e-2)" "unprognostic (1.71e-1)" "unprognostic (8.75e-2)" "unprognostic (6.16e-2)" "unprognostic (3.61e-2)" C6orf136 Em:AB023049.8 ENSG00000204564 "Chromosome 6 open reading frame 136" Q5SQH8 6 30647039-30653210 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 40.5;Enterocytes: 40.2;Oocytes: 59.9;Parietal cells: 30.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046804 Uncertain NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 98: Neurons - Neurotransmission & signaling" "HPA046804: " "unprognostic (1.22e-1)" "unprognostic (2.34e-1)" "unprognostic (4.06e-2)" "unprognostic (5.48e-3)" "unprognostic (1.05e-1)" "unprognostic (4.66e-2)" "unprognostic (3.21e-1)" "unprognostic (2.31e-1)" "unprognostic (5.66e-2)" "unprognostic (2.19e-3)" "unprognostic (4.43e-2)" "unprognostic (4.27e-1)" "unprognostic (1.05e-1)" "unprognostic (3.68e-2)" "unprognostic (1.74e-2)" "unprognostic (1.25e-1)" "unprognostic (2.58e-1)" "unprognostic (1.32e-1)" "unprognostic (1.01e-1)" "unprognostic (8.49e-3)" "unprognostic (3.53e-2)" "unprognostic (5.64e-3)" "unprognostic (1.78e-2)" "unprognostic (3.20e-1)" "unprognostic (1.54e-1)" "unprognostic (6.40e-2)" "unprognostic (2.95e-1)" "unprognostic (1.71e-2)" "unprognostic (1.53e-1)" "unprognostic (3.32e-1)" "unprognostic (2.49e-1)" C6orf141 MGC46457 ENSG00000197261 "Chromosome 6 open reading frame 141" Q5SZD1 6 49550666-49561907 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 8.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 48.4;Brain inhibitory neurons: 42.6;Endometrial ciliated cells: 37.3;Endometrial glandular cells: 57.7;Endometrial luminal cells: 51.3;Foveolar cells: 45.0;Lymphatic endothelial cells: 70.7;Medullary thymic epithelial cells: 36.0;Neuroendocrine cells: 101.6;Ocular epithelial cells: 42.0;Pancreatic duct cells: 88.3;Pituitary stem cells: 32.1;Sertoli cells: 83.8;Suprabasal keratinocytes: 36.3;Urothelial cells: 34.3" "Group enriched" "Detected in some" 4 "eccentric medium spiny neuron: 75.2;lower rhombic lip: 68.0;medium spiny neuron: 82.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "basal ganglia: 11.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Stomach - Gastric mucous cells, Testis - Sertoli cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA036199 Uncertain Approved "Nuclear membrane" NA NA "Cluster 2: Non-specific - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" 18 "Nuclear membrane" "HPA036199: " "potential prognostic favorable (2.26e-4)" "unprognostic (1.82e-1)" "unprognostic (7.74e-2)" "unprognostic (5.84e-2)" "unprognostic (4.43e-2)" "unprognostic (3.92e-2)" "potential prognostic unfavorable (5.59e-4)" "unprognostic (8.71e-3)" "unprognostic (8.87e-2)" "unprognostic (1.08e-1)" "unprognostic (4.87e-2)" "unprognostic (3.27e-1)" "unprognostic (1.57e-3)" "unprognostic (1.86e-1)" "unprognostic (1.02e-2)" "unprognostic (2.37e-2)" "unprognostic (1.99e-3)" "potential prognostic favorable (6.80e-4)" "unprognostic (2.96e-2)" C6orf15 STG ENSG00000204542 "Chromosome 6 open reading frame 15" Q6UXA7 6 31111223-31112575 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "cervix: 5.2;lymphoid tissue: 3.2;skin 1: 6.3" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 23.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 20.9;colorectal cancer: 26.9;Esophageal cancer: 22.8" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Not detected" "Not detected" HPA001436 Uncertain "Secreted to extracellular matrix" "No annotated function" NA NA "Cluster 58: Skin - Keratinization" "Cluster 32: Non-specific - Cell proliferation" 8 "HPA001436: " "unprognostic (5.77e-1)" "unprognostic (2.91e-2)" "unprognostic (8.69e-1)" "unprognostic (5.44e-2)" "unprognostic (8.10e-1)" "unprognostic (2.92e-1)" "potential prognostic unfavorable (5.24e-5)" "unprognostic (1.72e-1)" "unprognostic (1.98e-1)" "unprognostic (1.56e-1)" "unprognostic (3.65e-2)" "unprognostic (6.32e-2)" "unprognostic (9.89e-2)" "unprognostic (7.13e-2)" "unprognostic (1.55e-1)" "unprognostic (2.46e-1)" "unprognostic (3.16e-1)" C6orf163 ENSG00000203872 "Chromosome 6 open reading frame 163" Q5TEZ5 6 87344813-87365463 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 7.2" "Group enriched" "Detected in some" 13 "Early spermatids: 16.3;Late spermatids: 15.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Testicular Germ Cell Tumor (TCGA): 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in single" 4 "basal ganglia: 1.5" "Low region specificity" "Detected in many" "HPA044797, HPA052927" Uncertain Uncertain Nucleoplasm NA NA "Cluster 44: Bone marrow - Nuclear processes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" Nucleoplasm "HPA044797: , HPA052927: " "unprognostic (1.68e-1)" "unprognostic (2.67e-1)" "unprognostic (6.59e-2)" "unprognostic (5.57e-2)" "unprognostic (6.38e-2)" "unprognostic (3.83e-2)" C6orf226 LOC441150 ENSG00000221821 "Chromosome 6 open reading frame 226" Q5I0X4 6 42890265-42890821 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 69.2;Platelets: 84.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045350 Approved Approved "Nuclear speckles" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 28: Non-specific - Nuclear processes" "Cluster 97: Non-specific - Cellular respiration" 10 "Nuclear speckles" "HPA045350: " "unprognostic (1.45e-2)" "unprognostic (2.04e-3)" "unprognostic (1.75e-1)" "potential prognostic favorable (6.73e-4)" "unprognostic (1.06e-1)" "unprognostic (7.80e-2)" "unprognostic (2.09e-1)" "unprognostic (2.70e-1)" "unprognostic (4.20e-2)" "unprognostic (9.62e-2)" "unprognostic (7.84e-3)" "unprognostic (1.32e-1)" "potential prognostic favorable (7.04e-6)" "unprognostic (5.38e-2)" "unprognostic (1.69e-1)" "unprognostic (2.50e-3)" "unprognostic (1.44e-1)" "unprognostic (1.41e-2)" "unprognostic (8.89e-2)" "unprognostic (3.21e-3)" "unprognostic (8.00e-2)" "unprognostic (1.57e-3)" "unprognostic (1.18e-1)" "unprognostic (1.53e-2)" "unprognostic (3.49e-2)" "unprognostic (8.44e-2)" "unprognostic (1.62e-3)" "unprognostic (3.51e-1)" "unprognostic (2.71e-1)" "unprognostic (3.63e-2)" "unprognostic (1.28e-1)" C6orf47 "D6S53E, G4" ENSG00000204439 "Chromosome 6 open reading frame 47" O95873 6 31658298-31660778 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 4.4;Bergmann glia: 8.3;Brain excitatory neurons: 3.6;Brain inhibitory neurons: 4.2;Choroid plexus epithelial cells: 2.7;Distal convoluted tubule cells: 3.1;Ependymal cells: 3.0;Loop of henle epithelial cells: 4.1;Microglia: 7.4;Oligodendrocyte progenitor cells: 5.4;Oligodendrocytes: 7.7;Other brain neurons: 3.9;Papillary tip epithelial cells: 4.4;Podocytes: 3.6;Proximal tubule cells: 3.9;Renal collecting duct intercalated cells: 3.2;Renal collecting duct principal cells: 3.8;Renal connecting tubule cells: 2.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" HPA045281 Uncertain Approved Cytosol NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 2: Neurons - Nucleosome" "Cluster 28: Non-specific - Nuclear processes" "Cluster 98: Neurons - Neurotransmission & signaling" 4 Cytosol "HPA045281: " "unprognostic (4.30e-3)" "unprognostic (1.04e-1)" "unprognostic (7.49e-2)" "unprognostic (1.08e-1)" "unprognostic (5.70e-2)" "unprognostic (5.08e-2)" "unprognostic (2.10e-1)" "unprognostic (2.44e-2)" "unprognostic (4.82e-2)" "unprognostic (2.86e-2)" "unprognostic (2.05e-1)" "unprognostic (2.76e-1)" "unprognostic (3.03e-2)" "unprognostic (3.62e-1)" "unprognostic (6.96e-2)" "unprognostic (3.80e-2)" "unprognostic (9.71e-2)" "unprognostic (2.75e-2)" "unprognostic (7.60e-2)" "unprognostic (9.42e-2)" "unprognostic (2.72e-1)" "unprognostic (3.66e-1)" "unprognostic (2.67e-1)" "unprognostic (1.78e-1)" "unprognostic (3.23e-1)" C6orf52 ENSG00000137434 "Chromosome 6 open reading frame 52" Q5T4I8 6 10671418-10694797 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "testis: 13.1" "Cell type enriched" "Detected in many" 16 "Oocytes: 1243.4" "Cell type enhanced" "Detected in many" "ependymal cell: 23.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "eosinophil: 2.7;T-reg: 4.2" "Group enriched" "Detected in many" 5 "granulocytes: 2.7;T-cells: 4.2" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Testis - Early spermatids" "Not detected" "Not detected" HPA051142 Uncertain Approved "Nuclear speckles,Intermediate filaments" No No "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 67: Testis - Mixed function" "Cluster 3: Choroid plexus - Cilium" "Cluster 23: Non-specific - Transcription" "Cluster 41: Oocytes - Oogenesis" "Nuclear speckles" "Intermediate filaments" "HPA051142: " "unprognostic (6.18e-2)" "unprognostic (1.23e-2)" "unprognostic (4.60e-2)" "unprognostic (4.29e-3)" "unprognostic (2.08e-1)" "unprognostic (1.49e-1)" "unprognostic (1.73e-1)" "unprognostic (2.52e-2)" "unprognostic (9.55e-2)" "unprognostic (1.64e-1)" "unprognostic (1.66e-2)" "unprognostic (4.39e-2)" "unprognostic (8.22e-3)" "unprognostic (1.15e-1)" "unprognostic (1.26e-1)" "unprognostic (8.86e-3)" "unprognostic (5.87e-2)" "unprognostic (1.74e-1)" C6orf58 LEG1 ENSG00000184530 "Chromosome 6 open reading frame 58" Q6P5S2 6 127519455-127591820 "Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "salivary gland: 2318.7" "Cell type enhanced" "Detected in many" "Gastric chief cells: 83.0;Mucous neck cells: 425.5;Neuroendocrine cells: 24.5;Submucosal glandular cells: 159.0" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 12.0" "Group enriched" "Detected in some" 6 "Pancreatic Adenocarcinoma (TCGA): 40.6;Stomach Adenocarcinoma (TCGA): 27.2" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Kidney cancer: 2.3;lymphoma: 3.3" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA036263, HPA041449" Enhanced Approved Nucleoplasm,Vesicles,Cytosol "Secreted to digestive system" "Developmental protein" NA NA 33000 "Cluster 60: Stomach - Digestion" "Cluster 53: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 9 "Vesicles, Cytosol" Nucleoplasm "HPA036263: , HPA041449: " "unprognostic (9.34e-3)" "unprognostic (6.52e-3)" "unprognostic (1.89e-1)" "unprognostic (8.13e-2)" "unprognostic (1.21e-1)" "unprognostic (4.16e-2)" "unprognostic (4.36e-3)" "unprognostic (8.62e-2)" C6orf62 "DKFZP564G182, FLJ12619, XTP12" ENSG00000112308 "Chromosome 6 open reading frame 62" Q9GZU0 6 24704861-24719998 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Kupffer cells: 704.1;Neutrophils: 391.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030564, HPA030566" Supported Approved Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 39: Astrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 1 Cytosol "HPA030564: , HPA030566: " "unprognostic (1.65e-3)" "unprognostic (2.13e-2)" "unprognostic (5.95e-2)" "unprognostic (3.25e-1)" "unprognostic (2.51e-1)" "unprognostic (8.70e-2)" "unprognostic (3.18e-1)" "unprognostic (1.04e-1)" "unprognostic (1.52e-2)" "potential prognostic unfavorable (4.39e-4)" "potential prognostic favorable (2.85e-4)" "unprognostic (2.42e-2)" "unprognostic (1.74e-1)" "unprognostic (2.74e-3)" "unprognostic (1.44e-1)" "unprognostic (1.34e-1)" "unprognostic (8.62e-2)" "unprognostic (1.09e-1)" "unprognostic (2.27e-1)" "unprognostic (1.88e-2)" "unprognostic (8.69e-2)" "unprognostic (2.90e-2)" "unprognostic (2.60e-2)" "unprognostic (1.53e-2)" "unprognostic (3.85e-3)" "unprognostic (3.58e-1)" "unprognostic (1.19e-1)" "unprognostic (4.79e-2)" "unprognostic (3.07e-1)" "unprognostic (2.09e-1)" "unprognostic (1.80e-1)" C6orf89 "BRAP, FLJ25357" ENSG00000198663 "Chromosome 6 open reading frame 89" Q6UWU4 6 36871870-36928964 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 434.3;Late spermatids: 1013.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Fibroblasts, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012548 Uncertain NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 61: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" "HPA012548: " "unprognostic (3.65e-1)" "unprognostic (1.01e-1)" "unprognostic (2.27e-1)" "unprognostic (5.72e-2)" "unprognostic (5.68e-2)" "unprognostic (6.88e-3)" "unprognostic (4.64e-2)" "unprognostic (1.11e-1)" "unprognostic (3.75e-1)" "unprognostic (6.30e-2)" "validated prognostic favorable (4.44e-6)" "validated prognostic favorable (2.78e-4)" "unprognostic (2.62e-3)" "unprognostic (7.83e-2)" "unprognostic (4.86e-2)" "unprognostic (2.56e-1)" "unprognostic (2.90e-2)" "unprognostic (2.20e-1)" "unprognostic (3.37e-2)" "unprognostic (1.01e-1)" "unprognostic (2.51e-2)" "unprognostic (2.96e-1)" "unprognostic (4.62e-1)" "unprognostic (1.25e-1)" "unprognostic (1.03e-1)" "unprognostic (9.80e-2)" "unprognostic (1.39e-2)" "unprognostic (4.93e-2)" "unprognostic (2.44e-1)" "unprognostic (4.08e-2)" "unprognostic (2.84e-1)" C7 ENSG00000112936 "Complement C7" P10643 5 40909492-41020216 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement alternate pathway, Complement pathway, Cytolysis, Immunity, Innate immunity" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 861.4" "Cell type enhanced" "Detected in many" "Adipocytes: 276.1;Fibro-adipogenic progenitors: 413.7;Fibroblasts: 761.2;Hepatic stellate cells: 761.7;Leydig cells: 981.3;Lymphatic endothelial cells: 153.9;Ovarian stromal cells: 355.1;Pericytes: 163.0;Vascular endothelial cells: 175.9" "Cell type enriched" "Detected in some" 27 "fibroblast: 381.7" "Cancer enhanced" "Detected in many" "Pancreatic Adenocarcinoma (TCGA): 85.4" "Region enhanced" "Detected in many" "choroid plexus: 33.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 12 "Neuroblastoma: 50.9" "Adrenal gland - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblasts_2, Pancreas - Fibroblasts, Prostate - Fibroblasts, Spleen - Fibroblasts_2" "Not detected" "Not detected" "Region enhanced" "Detected in many" "spinal cord: 18.6" HPA001465 Approved "Secreted to blood" "Complement pathway" NA NA 18000000000 "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 8: Immune cells - Immune response" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 1 "HPA001465: " "unprognostic (9.33e-3)" "unprognostic (5.01e-2)" "unprognostic (5.94e-2)" "unprognostic (3.49e-2)" "unprognostic (7.43e-2)" "unprognostic (1.63e-2)" "unprognostic (1.16e-2)" "unprognostic (2.79e-1)" "unprognostic (1.04e-1)" "unprognostic (7.00e-2)" "unprognostic (9.53e-3)" "unprognostic (1.58e-3)" "potential prognostic favorable (2.61e-6)" "potential prognostic favorable (5.59e-5)" "unprognostic (1.16e-1)" "unprognostic (1.05e-2)" "unprognostic (1.96e-1)" "unprognostic (4.29e-2)" "unprognostic (7.59e-2)" "unprognostic (9.22e-2)" "unprognostic (1.15e-1)" "unprognostic (2.02e-3)" "potential prognostic favorable (4.64e-4)" "unprognostic (4.71e-2)" "unprognostic (2.43e-3)" "unprognostic (1.23e-1)" "unprognostic (1.12e-1)" C7orf25 MGC2821 ENSG00000136197 "Chromosome 7 open reading frame 25" Q9BPX7 7 42909273-42912305 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Astrocytes: 5.7;Bergmann glia: 7.7;Brain excitatory neurons: 6.6;Brain inhibitory neurons: 6.0;Choroid plexus epithelial cells: 4.0;Ependymal cells: 3.5;Megakaryocytes: 6.2;Microglia: 3.6;Oligodendrocyte progenitor cells: 7.4;Oligodendrocytes: 8.8;Other brain neurons: 8.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 37.9" "Lineage enriched" "Detected in all" 15 "granulocytes: 37.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020120, HPA049635" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 32: Basophils - Transcription" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 67: Non-specific - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" 3 Nucleoplasm Cytosol "HPA020120: , HPA049635: " "unprognostic (9.90e-3)" "unprognostic (3.01e-1)" "unprognostic (5.91e-2)" "unprognostic (2.20e-2)" "unprognostic (3.60e-2)" "unprognostic (1.17e-2)" "unprognostic (1.40e-2)" "unprognostic (8.91e-2)" "unprognostic (8.19e-2)" "unprognostic (1.03e-1)" "unprognostic (1.12e-2)" "unprognostic (7.53e-2)" "unprognostic (2.58e-1)" "unprognostic (3.16e-1)" "unprognostic (7.67e-2)" "unprognostic (8.78e-3)" "unprognostic (7.93e-2)" "unprognostic (2.54e-1)" "unprognostic (1.30e-2)" "unprognostic (3.05e-2)" "unprognostic (5.90e-2)" "unprognostic (7.29e-3)" "unprognostic (3.92e-2)" "unprognostic (3.38e-1)" "unprognostic (1.48e-2)" "unprognostic (3.05e-1)" "unprognostic (1.06e-1)" "unprognostic (1.52e-1)" "unprognostic (1.06e-1)" "unprognostic (2.49e-3)" "unprognostic (2.69e-1)" C7orf31 ENSG00000153790 "Chromosome 7 open reading frame 31" Q8N865 7 25134692-25180356 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "testis: 61.2" "Group enriched" "Detected in many" 7 "Early spermatids: 539.3;Late spermatids: 1448.0" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 25.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA020346 Uncertain Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 57: Testis - Spermatogenesis" "Cluster 54: Immune cells - T cell receptor" "Cluster 67: Non-specific - Unknown function" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 15 "Nucleoplasm, Mitochondria" Cytosol "HPA020346: " "unprognostic (5.89e-2)" "unprognostic (8.52e-2)" "unprognostic (2.37e-1)" "unprognostic (1.13e-1)" "unprognostic (6.33e-2)" "unprognostic (5.44e-2)" "unprognostic (1.15e-3)" "potential prognostic unfavorable (7.02e-5)" "unprognostic (3.54e-1)" "unprognostic (5.37e-3)" "validated prognostic favorable (9.17e-5)" "validated prognostic favorable (9.20e-4)" "potential prognostic favorable (7.45e-4)" "unprognostic (9.57e-3)" "unprognostic (6.18e-2)" "unprognostic (1.19e-2)" "unprognostic (3.84e-1)" "unprognostic (3.37e-2)" "unprognostic (1.66e-2)" "unprognostic (2.53e-1)" "unprognostic (2.38e-2)" "unprognostic (2.03e-2)" "unprognostic (2.52e-1)" "unprognostic (4.06e-2)" "unprognostic (2.63e-3)" "unprognostic (9.08e-3)" "unprognostic (6.73e-2)" "unprognostic (3.20e-2)" "unprognostic (2.86e-2)" "unprognostic (4.47e-2)" "unprognostic (6.84e-2)" C7orf33 ENSG00000170279 "Chromosome 7 open reading frame 33" Q8WU49 7 148590766-148615860 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 6 "retina: 1.3" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 49.7;Early spermatids: 7.5;Extravillous trophoblasts: 17.7;Late spermatids: 9.0;Migrating cytotrophoblasts: 6.1;Myonuclei: 3.7;Rod photoreceptor cells: 2.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "lymphoma: 1.1" HPA047587 Approved "Acrosome,Equatorial segment" NA NA "Cluster 42: Retina - Visual perception" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 79: Photoreceptor cells - Phototransduction" 1 "Acrosome, Equatorial segment" "HPA047587: " C7orf50 "MGC11257, YCR016W" ENSG00000146540 "Chromosome 7 open reading frame 50" Q9BRJ6 7 996986-1138260 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052281 Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 67: Non-specific - Unknown function" "Cluster 75: Non-specific - Chaperones and protein folding" 60 "Nucleoplasm, Nucleoli" "HPA052281: " "unprognostic (4.23e-2)" "unprognostic (2.56e-1)" "unprognostic (2.50e-1)" "unprognostic (1.44e-2)" "unprognostic (3.06e-2)" "unprognostic (1.76e-1)" "unprognostic (4.28e-3)" "unprognostic (2.60e-2)" "unprognostic (1.51e-3)" "unprognostic (7.65e-3)" "unprognostic (3.86e-2)" "unprognostic (2.15e-1)" "unprognostic (4.91e-3)" "validated prognostic unfavorable (5.40e-4)" "validated prognostic unfavorable (6.30e-4)" "unprognostic (2.57e-1)" "unprognostic (3.06e-2)" "unprognostic (2.25e-1)" "unprognostic (1.63e-1)" "unprognostic (6.47e-2)" "unprognostic (1.34e-1)" "potential prognostic favorable (4.96e-4)" "unprognostic (1.80e-2)" "unprognostic (8.94e-2)" "unprognostic (2.50e-1)" "unprognostic (7.44e-2)" "unprognostic (5.60e-2)" "unprognostic (1.99e-2)" "unprognostic (1.45e-1)" "unprognostic (2.24e-1)" "unprognostic (2.35e-2)" C7orf57 ENSG00000164746 "Chromosome 7 open reading frame 57" Q8NEG2 7 48035511-48061304 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 7.4;fallopian tube: 13.1" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 41.5;Endometrial ciliated cells: 80.2;Ependymal cells: 137.5;Epididymal efferent duct ciliated cells: 107.9;Esophageal apical cells: 30.2;Fallopian tube ciliated cells: 149.7;Late primary spermatocytes: 36.8;Respiratory ciliated cells: 225.2;Respiratory deuterosomal cells: 46.6" "Cell type enriched" "Detected in many" 4 "ependymal cell: 162.7" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 6.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA021286 Enhanced Approved "Primary cilium,Primary cilium transition zone,Basal body,Cytosol" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 72: Neuronal - Signal transduction" "Cluster 107: Ciliated cells - Cilia assembly & function" Cytosol "Primary cilium, Primary cilium transition zone, Basal body" "HPA021286: " "unprognostic (1.18e-1)" "potential prognostic favorable (8.81e-4)" "unprognostic (1.37e-2)" "unprognostic (7.95e-3)" "unprognostic (6.28e-2)" "unprognostic (7.52e-2)" "unprognostic (1.44e-1)" "unprognostic (1.20e-1)" "potential prognostic favorable (2.30e-4)" "unprognostic (7.60e-2)" "unprognostic (3.73e-2)" C8A ENSG00000157131 "Complement C8 alpha chain" P07357 1 56854768-56918223 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" "Complement alternate pathway, Complement pathway, Cytolysis, Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 277 "liver: 464.3" "Cell type enriched" "Detected in some" 33 "Hepatocytes: 385.0" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 123 "Liver Hepatocellular Carcinoma (TCGA): 105.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA077621 Supported "Plasma membrane" "Secreted to blood" "Complement pathway" NA NA 15000000000 "Cluster 53: Liver - Plasma proteins" "Cluster 18: Liver cancer - Metabolism" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 7 "Plasma membrane" "HPA077621: " "unprognostic (9.39e-3)" "potential prognostic favorable (1.71e-6)" C8B ENSG00000021852 "Complement C8 beta chain" P07358 1 56929207-56974383 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement alternate pathway, Complement pathway, Cytolysis, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 126 "liver: 607.6" "Cell type enriched" "Detected in some" 17 "Hepatocytes: 350.5" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 93 "Liver Hepatocellular Carcinoma (TCGA): 177.2" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 23 "basophil: 2.3" "Lineage enriched" "Detected in single" 23 "granulocytes: 2.3" "Cancer enriched" "Detected in single" 11 "liver cancer: 1.1" "Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA023694 Supported "Secreted to blood" "Complement pathway" NA NA 15000000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 18: Liver cancer - Metabolism" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 1 "HPA023694: " "validated prognostic favorable (2.99e-4)" "validated prognostic favorable (9.22e-8)" "unprognostic (2.41e-3)" "unprognostic (6.11e-2)" C8G ENSG00000176919 "Complement C8 gamma chain" P07360 9 136945185-136946975 "Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement alternate pathway, Complement pathway, Cytolysis, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "liver: 522.4" "Cell type enriched" "Detected in some" 9 "Hepatocytes: 1125.9" "Low cell type specificity" "Detected in some" "Cancer enriched" "Detected in some" 61 "Liver Hepatocellular Carcinoma (TCGA): 321.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Gastric cancer: 6.2;liver cancer: 2.1" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046269 Approved "Secreted to blood" "Complement pathway" NA NA 5500000000 "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 3 "HPA046269: " "unprognostic (2.28e-1)" "unprognostic (9.72e-2)" "unprognostic (1.36e-2)" "unprognostic (3.98e-3)" "unprognostic (2.23e-2)" "potential prognostic favorable (3.25e-4)" "unprognostic (1.30e-2)" "unprognostic (1.19e-1)" "unprognostic (2.46e-1)" "unprognostic (2.24e-1)" "unprognostic (2.28e-1)" C8orf33 FLJ20989 ENSG00000182307 "Chromosome 8 open reading frame 33" Q9H7E9 8 145052465-145066685 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024812, HPA026104" Approved Uncertain "Nucleoplasm,Plasma membrane" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 32 "Nucleoplasm, Plasma membrane" "HPA024812: , HPA026104: " "unprognostic (8.11e-2)" "potential prognostic unfavorable (2.07e-4)" "unprognostic (4.13e-2)" "unprognostic (6.86e-3)" "unprognostic (3.43e-2)" "unprognostic (2.32e-2)" "unprognostic (5.46e-2)" "unprognostic (4.49e-2)" "unprognostic (3.66e-3)" "unprognostic (3.02e-2)" "unprognostic (1.13e-2)" "unprognostic (2.77e-1)" "unprognostic (1.81e-2)" "potential prognostic unfavorable (4.61e-5)" "unprognostic (2.32e-3)" "unprognostic (1.34e-2)" "unprognostic (1.54e-1)" "unprognostic (3.44e-1)" "unprognostic (1.36e-1)" "unprognostic (3.86e-2)" "unprognostic (1.94e-1)" "unprognostic (2.37e-3)" "unprognostic (3.82e-2)" "unprognostic (3.15e-1)" "unprognostic (1.02e-1)" "unprognostic (3.43e-1)" "unprognostic (1.17e-1)" "unprognostic (1.96e-2)" "unprognostic (2.45e-1)" "unprognostic (6.80e-2)" "unprognostic (9.18e-2)" C8orf34 "vest-1, VEST1" ENSG00000165084 "Chromosome 8 open reading frame 34" Q49A92 8 68330955-68819023 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 8.6;parathyroid gland: 6.9" "Cell type enhanced" "Detected in many" "Adipocytes: 210.7;Alveolar cells type 2: 306.1;Brain excitatory neurons: 271.6;Brain inhibitory neurons: 234.6;Endometrial ciliated cells: 450.0;Ependymal cells: 2521.4;Fallopian tube ciliated cells: 446.6;Respiratory ciliated cells: 961.8;Thyrotrophs: 227.3;Transitional alveolar cells: 374.0" "Cell type enhanced" "Detected in all" "ependymal cell: 2549.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Kidney - Fibroblasts, Minor Salivary Gland - Fibroblasts, Pituitary gland - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044420, HPA053065" Uncertain Approved "Nucleoplasm,Nucleoli,Golgi apparatus" No NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 29: Forebrain - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 34: Ciliated cells - Cilia assembly & function" "Nucleoplasm, Nucleoli" "Golgi apparatus" "HPA044420: , HPA053065: " "unprognostic (3.66e-2)" "unprognostic (6.14e-2)" "unprognostic (2.44e-1)" "unprognostic (1.98e-1)" "unprognostic (1.72e-2)" "unprognostic (1.71e-1)" "unprognostic (1.63e-3)" "unprognostic (1.50e-1)" "unprognostic (9.46e-2)" "unprognostic (1.88e-2)" "unprognostic (3.91e-2)" "unprognostic (2.46e-2)" "unprognostic (1.73e-1)" "unprognostic (2.26e-1)" "unprognostic (1.48e-2)" C8orf44-SGK3 ENSG00000288602 "C8orf44-SGK3 readthrough" 8 66667596-66860472 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 31.0;Myonuclei: 42.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 31.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA006699, HPA027146" Approved Uncertain Nucleoplasm,Vesicles NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 22: Epididymis - Mixed function" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" Vesicles Nucleoplasm "HPA006699: , HPA027146: " "unprognostic (1.83e-1)" "unprognostic (1.13e-2)" "unprognostic (3.64e-2)" "unprognostic (5.00e-3)" "unprognostic (1.91e-1)" "unprognostic (2.81e-1)" "unprognostic (1.79e-1)" "potential prognostic unfavorable (6.85e-5)" "unprognostic (3.34e-3)" "unprognostic (7.69e-2)" "unprognostic (2.05e-1)" "unprognostic (2.89e-3)" "unprognostic (1.77e-1)" "unprognostic (2.08e-1)" "unprognostic (8.45e-2)" "unprognostic (3.85e-1)" "unprognostic (1.68e-1)" "unprognostic (5.44e-2)" "unprognostic (6.42e-3)" "unprognostic (9.10e-2)" "unprognostic (3.27e-1)" "unprognostic (1.77e-1)" "unprognostic (1.66e-1)" "unprognostic (2.86e-1)" "unprognostic (1.99e-1)" "unprognostic (1.42e-1)" C8orf48 FLJ25402 ENSG00000164743 "Chromosome 8 open reading frame 48" Q96LL4 8 13566869-13568288 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 6.5" "Group enriched" "Detected in some" 4 "Early spermatids: 29.3;Late primary spermatocytes: 47.5;Late spermatids: 88.8" "Cell type enriched" "Detected in some" 4 "Bergmann glia: 10.6" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 4.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Pituitary gland - Undifferentiated cells (Pituitary gland), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026107, HPA027440" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 30: White matter - Myelination" "Cluster 69: Skin cancer - ECM organization" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 17 Cytosol Nucleoplasm "HPA026107: , HPA027440: " "unprognostic (9.19e-2)" "unprognostic (1.63e-1)" "unprognostic (9.24e-3)" "unprognostic (1.59e-3)" "unprognostic (3.31e-2)" "unprognostic (3.98e-1)" "unprognostic (3.22e-1)" "unprognostic (4.28e-2)" "unprognostic (1.43e-1)" "unprognostic (1.14e-1)" "unprognostic (2.75e-1)" "unprognostic (1.44e-1)" "unprognostic (9.11e-3)" C8orf58 FLJ34715 ENSG00000241852 "Chromosome 8 open reading frame 58" Q8NAV2 8 22599599-22604150 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 16.4;Cytotrophoblasts: 28.3;Decidual stromal cells: 18.8;Extravillous trophoblasts: 41.1;Migrating cytotrophoblasts: 43.9;Podocytes: 25.6;Syncytiotrophoblasts: 62.3" "Cell type enhanced" "Detected in many" "pericyte: 9.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 1.2" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA024667, HPA028286" Uncertain Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 25: Non-specific - Transcription" "Cluster 3: Rhabdoid - Membrane components" "Cluster 63: Cytotrophoblasts - Basic cellular functions" "Nuclear bodies" Nucleoplasm "HPA024667: , HPA028286: " "unprognostic (6.95e-3)" "unprognostic (2.01e-2)" "potential prognostic favorable (8.72e-4)" "unprognostic (7.23e-2)" "unprognostic (1.47e-2)" "unprognostic (1.29e-1)" "unprognostic (1.71e-2)" "unprognostic (2.81e-1)" "unprognostic (3.26e-1)" "unprognostic (3.43e-1)" "unprognostic (5.37e-2)" "unprognostic (1.50e-1)" "unprognostic (1.28e-1)" "unprognostic (1.01e-1)" "unprognostic (4.03e-2)" "unprognostic (2.16e-1)" "unprognostic (1.13e-1)" "unprognostic (2.28e-1)" "unprognostic (4.00e-1)" "unprognostic (3.36e-2)" "unprognostic (6.01e-2)" "unprognostic (7.15e-2)" "unprognostic (4.88e-3)" "unprognostic (5.19e-2)" "unprognostic (1.19e-1)" "unprognostic (1.69e-1)" "unprognostic (2.57e-1)" "unprognostic (2.19e-1)" "unprognostic (1.62e-1)" "unprognostic (6.53e-2)" "unprognostic (2.36e-2)" C8orf74 ENSG00000171060 "Chromosome 8 open reading frame 74" Q6P047 8 10672628-10700590 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 162 "testis: 16.1" "Group enriched" "Detected in some" 4 "Early spermatids: 78.4;Late spermatids: 209.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pituitary gland - Corticotropes, Skin - Keratinocyte (granular), Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA027986 Uncertain Uncertain Nucleoplasm NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 10 Nucleoplasm "HPA027986: " C8orf76 FLJ14825 ENSG00000189376 "Chromosome 8 open reading frame 76" Q96K31 8 123219967-123241377 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 85.8;Retinal horizontal cells: 80.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023708 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 40: Non-specific - Unknown function" "Cluster 84: Apical squamous epithelium - Cornification" 2 Nucleoplasm Cytosol "HPA023708: " "unprognostic (1.94e-1)" "potential prognostic unfavorable (7.27e-6)" "unprognostic (2.79e-1)" "unprognostic (4.72e-2)" "unprognostic (2.17e-1)" "unprognostic (2.98e-1)" "unprognostic (1.76e-2)" "unprognostic (4.00e-2)" "unprognostic (1.57e-2)" "unprognostic (6.36e-3)" "validated prognostic unfavorable (1.89e-4)" "validated prognostic unfavorable (2.14e-4)" "potential prognostic unfavorable (9.58e-4)" "unprognostic (1.87e-3)" "unprognostic (1.08e-3)" "unprognostic (1.34e-3)" "unprognostic (2.93e-2)" "unprognostic (7.98e-2)" "unprognostic (1.62e-2)" "unprognostic (3.40e-1)" "unprognostic (9.83e-2)" "unprognostic (2.16e-1)" "potential prognostic unfavorable (5.64e-6)" "unprognostic (9.75e-2)" "unprognostic (5.59e-2)" "unprognostic (3.54e-2)" "unprognostic (3.37e-2)" "unprognostic (1.07e-1)" "unprognostic (1.34e-1)" "unprognostic (1.76e-1)" "unprognostic (4.32e-1)" C8orf82 MGC70857 ENSG00000213563 "Chromosome 8 open reading frame 82" Q6P1X6 8 144525733-144529132 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Parietal cells: 10.6;Prostatic club cells: 5.5" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB034331 Uncertain Approved Nucleoplasm NA NA "Cluster 70: Non-specific - Protein processing" "Cluster 6: Non-specific - Immune response" "Cluster 40: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 6 Nucleoplasm "CAB034331: " "unprognostic (6.48e-2)" "unprognostic (2.64e-1)" "unprognostic (1.92e-2)" "unprognostic (1.43e-1)" "unprognostic (1.34e-2)" "unprognostic (1.80e-1)" "unprognostic (7.71e-2)" "unprognostic (6.27e-3)" "unprognostic (5.96e-2)" "unprognostic (1.55e-2)" "unprognostic (3.23e-2)" "potential prognostic favorable (3.53e-4)" "unprognostic (3.21e-2)" "unprognostic (1.31e-1)" "unprognostic (2.28e-1)" "unprognostic (1.70e-1)" "unprognostic (1.31e-1)" "unprognostic (1.46e-1)" "unprognostic (1.16e-1)" "unprognostic (9.18e-2)" "unprognostic (1.60e-1)" "potential prognostic unfavorable (6.74e-4)" "unprognostic (7.51e-2)" "unprognostic (1.97e-1)" "unprognostic (3.09e-3)" "unprognostic (1.68e-2)" "unprognostic (5.86e-3)" "unprognostic (3.25e-1)" "unprognostic (1.01e-1)" "unprognostic (3.12e-2)" C8orf88 ENSG00000253250 "Chromosome 8 open reading frame 88" P0DMB2 8 90958471-90985238 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 85.6" "Group enriched" "Detected in many" 4 "Early spermatids: 686.7;Late primary spermatocytes: 704.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 3.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA078486 Enhanced Approved "Golgi apparatus,Cytosol" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 35: Non-specific - Mixed function" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 3: Rhabdoid - Membrane components" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" Cytosol "Golgi apparatus" "HPA078486: " "unprognostic (1.07e-1)" "unprognostic (1.01e-1)" "unprognostic (3.91e-1)" "unprognostic (2.40e-2)" "unprognostic (4.03e-2)" "unprognostic (1.48e-1)" "unprognostic (4.46e-2)" "unprognostic (6.75e-2)" "potential prognostic unfavorable (8.41e-4)" "unprognostic (4.00e-3)" "unprognostic (5.05e-2)" "unprognostic (6.94e-2)" "unprognostic (2.77e-1)" "unprognostic (1.53e-1)" "unprognostic (1.69e-2)" "unprognostic (2.36e-2)" "unprognostic (1.16e-2)" "unprognostic (2.81e-1)" "unprognostic (3.23e-1)" "unprognostic (5.52e-3)" "unprognostic (8.19e-2)" "unprognostic (2.68e-3)" "unprognostic (9.49e-2)" "unprognostic (1.38e-3)" "unprognostic (2.97e-2)" "unprognostic (4.37e-2)" "unprognostic (1.68e-3)" C8orf89 ENSG00000274443 "Chromosome 8 open reading frame 89" P0DMQ9 8 73241331-73259530 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 7 "testis: 7.1" "Cell type enriched" "Detected in some" 6 "Late primary spermatocytes: 62.3" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "memory B-cell: 2.7;naive B-cell: 4.8" "Lineage enriched" "Detected in single" 6 "B-cells: 4.8" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 57: Testis - Spermatogenesis" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" C8orf90 ENSG00000226490 "Chromosome 8 open reading frame 90" 8 141514638-141518737 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Tissue enriched" "Detected in some" 5 "testis: 12.9" "Group enriched" "Detected in some" 57 "Early spermatids: 184.7;Late primary spermatocytes: 223.5;Late spermatids: 72.0" "Cell type enhanced" "Detected in many" "lower rhombic lip: 6.2;mammillary body: 6.7;upper-layer intratelencephalic: 7.4" "Not detected" "Not detected" "Region enhanced" "Detected in many" "hypothalamus: 9.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Keratinocyte (granular), Testis - Late spermatids" "Not detected" "Not detected" NA NA "Cluster 67: Testis - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" C9 ENSG00000113600 "Complement C9" P02748 5 39284140-39371324 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement alternate pathway, Complement pathway, Cytolysis, Immunity, Innate immunity" "Age-related macular degeneration, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 263 "liver: 1222.6" "Cell type enriched" "Detected in some" 55 "Hepatocytes: 2516.7" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 7.2;fibroblast: 8.7" "Cancer enriched" "Detected in some" 72 "Liver Hepatocellular Carcinoma (TCGA): 113.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB002151, HPA029577" Uncertain "Secreted to blood" "Complement pathway" NA NA 69600000000 28000000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 59: Leukemia - T-cell receptor" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 6 "CAB002151: , HPA029577: " "unprognostic (1.09e-1)" "unprognostic (1.52e-1)" "unprognostic (2.45e-3)" C9orf131 MGC41945 ENSG00000174038 "Chromosome 9 open reading frame 131" Q5VYM1 9 35041095-35045986 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "testis: 33.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 30.2;Early spermatids: 128.6;Epicardial cells: 109.2;Late primary spermatocytes: 73.7;Late spermatids: 47.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 4.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 6.6" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA022029 Approved Mitochondria NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 57: Testis - Spermatogenesis" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" Mitochondria "HPA022029: " "unprognostic (2.85e-1)" "unprognostic (9.46e-2)" "unprognostic (2.39e-1)" "unprognostic (4.46e-1)" "unprognostic (5.99e-2)" "unprognostic (3.25e-2)" "unprognostic (2.65e-1)" "unprognostic (8.10e-2)" "unprognostic (6.62e-2)" C9orf152 bA470J20.2 ENSG00000188959 "Chromosome 9 open reading frame 152" Q5JTZ5 9 110190048-110208159 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 39.1;salivary gland: 23.9;stomach 1: 31.6" "Cell type enhanced" "Detected in many" "Colonocytes: 60.3;Enteric stem cells: 87.7;Enteric transient amplifying cells: 74.5;Gastric chief cells: 103.7;Gastric progenitor cells: 65.4;Goblet cells: 129.1;Mucous neck cells: 83.1;Paneth cells: 61.9;Parietal cells: 139.7;Respiratory ionocytes: 48.3;Respiratory secretory cells: 44.9" "Low cell type specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 42.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 21.0;Gastric cancer: 17.5;prostate cancer: 18.0" "Breast - Breast glandular cells, Colon - Colon enterocytes, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA050769 Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 17: Intestine - Digestion" "Cluster 6: Non-specific - Immune response" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 70: Intestinal goblet cells - Mucin production" 1 Nucleoplasm Nucleoli "HPA050769: " "unprognostic (1.73e-2)" "unprognostic (1.80e-2)" "unprognostic (3.68e-3)" "unprognostic (1.95e-1)" "unprognostic (1.94e-1)" "unprognostic (1.70e-2)" "unprognostic (1.25e-1)" "unprognostic (1.06e-1)" "unprognostic (1.43e-1)" "unprognostic (6.47e-2)" "unprognostic (1.32e-2)" "unprognostic (3.18e-1)" "unprognostic (9.73e-2)" "unprognostic (7.26e-2)" "unprognostic (1.11e-1)" "potential prognostic favorable (1.12e-4)" "unprognostic (1.09e-1)" "unprognostic (1.09e-1)" "unprognostic (3.52e-2)" "unprognostic (3.16e-1)" "potential prognostic favorable (1.91e-4)" C9orf153 bA507D14.1 ENSG00000187753 "Chromosome 9 open reading frame 153" Q5TBE3 9 86220265-86259657 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 19.2" "Group enriched" "Detected in many" 12 "Early spermatids: 679.5;Late primary spermatocytes: 261.2;Late spermatids: 503.1" "Cell type enhanced" "Detected in all" "pericyte: 40.5" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.6" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" HPA079466 Approved "Nucleoplasm,Nuclear bodies,Vesicles,Plasma membrane" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 57: Testis - Spermatogenesis" "Cluster 9: Non-specific - Receptor signaling" "Cluster 56: Non-specific - Sensory perception" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" "Nuclear bodies, Plasma membrane" "Nucleoplasm, Vesicles" "HPA079466: " "unprognostic (4.28e-2)" "unprognostic (3.79e-2)" "unprognostic (4.01e-2)" "unprognostic (5.98e-2)" C9orf24 "bA573M23.4, CBE1, MGC32921, MGC33614, NYD-SP22, SMRP1" ENSG00000164972 "Chromosome 9 open reading frame 24" Q8NCR6 9 34379019-34397828 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 60.7;choroid plexus: 226.2;fallopian tube: 102.1;testis: 73.9" "Cell type enhanced" "Detected in many" "Early spermatids: 860.7;Endometrial ciliated cells: 889.5;Epididymal efferent duct ciliated cells: 1288.1;Fallopian tube ciliated cells: 2177.7;Late spermatids: 4568.5;Respiratory ciliated cells: 1668.5" "Group enriched" "Detected in all" 6 "choroid plexus epithelial cell: 93.3;ependymal cell: 273.7" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 24.7;Uterine Corpus Endometrial Carcinoma (TCGA): 33.8" "Region enhanced" "Detected in all" "choroid plexus: 204.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA053008 Enhanced Supported "Nucleoplasm,Cytosol,Equatorial segment,Principal piece" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" 24 "Nucleoplasm, Principal piece" "Cytosol, Equatorial segment" "HPA053008: " "unprognostic (1.09e-1)" "unprognostic (1.10e-1)" "potential prognostic favorable (1.38e-4)" "unprognostic (1.72e-1)" "unprognostic (8.25e-2)" "unprognostic (1.25e-2)" "unprognostic (1.02e-1)" "unprognostic (3.45e-2)" "unprognostic (9.64e-2)" "unprognostic (3.20e-1)" "unprognostic (6.29e-2)" "unprognostic (7.34e-2)" "unprognostic (1.28e-1)" "unprognostic (5.82e-2)" "unprognostic (6.62e-2)" "unprognostic (2.73e-1)" "unprognostic (2.16e-3)" "potential prognostic favorable (2.50e-4)" "unprognostic (1.29e-1)" "unprognostic (1.31e-1)" "unprognostic (6.41e-2)" "unprognostic (5.71e-2)" "unprognostic (2.36e-2)" "unprognostic (7.41e-2)" C9orf40 FLJ10110 ENSG00000135045 "Chromosome 9 open reading frame 40" Q8IXQ3 9 74946583-74952912 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 31.6;Erythrocyte progenitors: 75.4;Late primary spermatocytes: 36.7;Migrating cytotrophoblasts: 29.5" "Cell type enhanced" "Detected in all" "endothelial cell: 33.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 2.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042167 Enhanced Approved Nucleoplasm,Centrosome,Cytosol NA NA 69000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" "Nucleoplasm, Cytosol" Centrosome "HPA042167: " "unprognostic (1.97e-1)" "unprognostic (6.78e-2)" "unprognostic (2.97e-1)" "unprognostic (1.38e-1)" "unprognostic (2.06e-1)" "unprognostic (6.28e-3)" "unprognostic (3.16e-2)" "unprognostic (2.25e-3)" "unprognostic (1.38e-1)" "unprognostic (1.91e-1)" "unprognostic (7.95e-3)" "unprognostic (2.35e-1)" "potential prognostic unfavorable (9.74e-4)" "validated prognostic unfavorable (1.41e-4)" "validated prognostic unfavorable (1.39e-5)" "potential prognostic unfavorable (3.30e-4)" "unprognostic (3.92e-2)" "unprognostic (5.79e-2)" "unprognostic (1.01e-1)" "unprognostic (1.44e-1)" "unprognostic (1.71e-3)" "unprognostic (1.13e-1)" "unprognostic (3.18e-1)" "unprognostic (6.04e-3)" "unprognostic (7.63e-3)" "unprognostic (7.50e-3)" "unprognostic (1.50e-2)" "unprognostic (5.30e-2)" "unprognostic (5.32e-2)" "unprognostic (7.16e-2)" "unprognostic (4.22e-1)" C9orf43 MGC17358 ENSG00000157653 "Chromosome 9 open reading frame 43" Q8TAL5 9 113410054-113429690 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 24 "testis: 44.0" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 61.8;Early spermatids: 101.2;Epicardial cells: 43.2;Late primary spermatocytes: 168.6;Late spermatids: 364.3" "Cell type enhanced" "Detected in many" "Bergmann glia: 10.7;ependymal cell: 14.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Not detected" "Not detected" HPA021310 Approved Cytosol NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 6: Testis - Spermatogenesis" "Cluster 46: Brainstem - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 1 Cytosol "HPA021310: " "unprognostic (3.10e-2)" "unprognostic (4.03e-2)" "unprognostic (4.26e-1)" "unprognostic (3.37e-1)" C9orf50 FLJ35803 ENSG00000179058 "Chromosome 9 open reading frame 50" Q5SZB4 9 129612225-129621101 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 7.5" "Cell type enriched" "Detected in some" 4 "Late spermatids: 390.4" "Group enriched" "Detected in some" 4 "astrocyte: 3.5;Bergmann glia: 5.0;ependymal cell: 7.4;oligodendrocyte precursor cell: 4.9" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 2.3;Kidney Renal Papillary Cell Carcinoma (TCGA): 2.1" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Enteric glia cells, Testis - Late spermatids" "Low region specificity" "Detected in some" HPA026743 Enhanced NA NA "Cluster 67: Testis - Mixed function" "Cluster 44: Non-specific - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" "HPA026743: " "unprognostic (2.30e-1)" "unprognostic (2.37e-3)" "unprognostic (3.24e-2)" "unprognostic (4.17e-3)" "unprognostic (4.79e-2)" "unprognostic (7.16e-2)" "unprognostic (1.36e-1)" "unprognostic (4.29e-1)" C9orf57 ENSG00000204669 "Chromosome 9 open reading frame 57" Q5W0N0 9 72051376-72072721 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 87 "testis: 11.3" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 6.9;Early primary spermatocytes: 7.6;Late primary spermatocytes: 39.1;Tuft cells: 11.5;Undifferentiated spermatogonia: 4.2" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 9: Non-specific - Receptor signaling" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" C9orf64 MGC10999 ENSG00000165118 "Chromosome 9 open reading frame 64" Q5T6V5 9 83938311-83956986 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Spleen - Macrophages, Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054903, HPA066190" Uncertain Approved "Golgi apparatus" NA NA 7300 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" "Golgi apparatus" "HPA054903: , HPA066190: " "unprognostic (2.67e-2)" "unprognostic (1.98e-1)" "unprognostic (2.81e-1)" "unprognostic (1.01e-1)" "unprognostic (1.60e-1)" "unprognostic (1.96e-2)" "unprognostic (6.57e-3)" "potential prognostic unfavorable (8.28e-5)" "unprognostic (8.75e-2)" "unprognostic (5.83e-2)" "validated prognostic favorable (4.03e-7)" "validated prognostic favorable (1.75e-4)" "unprognostic (5.31e-3)" "unprognostic (3.72e-3)" "potential prognostic unfavorable (8.87e-4)" "unprognostic (4.31e-2)" "unprognostic (2.42e-2)" "unprognostic (2.05e-1)" "unprognostic (1.57e-1)" "unprognostic (8.20e-2)" "unprognostic (1.76e-1)" "unprognostic (8.41e-3)" "unprognostic (8.22e-2)" "unprognostic (5.18e-1)" "unprognostic (9.24e-2)" "unprognostic (3.54e-2)" "unprognostic (2.26e-3)" "unprognostic (3.41e-2)" "unprognostic (1.32e-1)" "unprognostic (5.62e-2)" "unprognostic (4.49e-2)" C9orf72 "DENND9, DENNL72, MGC23980" ENSG00000147894 "C9orf72-SMCR8 complex subunit" Q96LT7 9 27535640-27573866 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Autophagy "Guanine-nucleotide releasing factor" "Amyotrophic lateral sclerosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "cDC: 333.9;Kupffer cells: 297.2;monocytes: 528.2;Neutrophils: 1758.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "basophil: 24.3;classical monocyte: 32.0;intermediate monocyte: 44.8;myeloid DC: 25.2;neutrophil: 34.5;non-classical monocyte: 37.0" "Group enriched" "Detected in all" 8 "dendritic cells: 25.2;granulocytes: 34.5;monocytes: 44.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023873 Uncertain Supported "Vesicles,Midbody ring,Cytosol" "Intracellular and membrane" Other Yes NA "Cluster 40: Monocytes - Innate immune response" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 25: Non-specific - Transcription" "Cluster 32: Non-specific - Cell proliferation" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 42 "Vesicles, Cytosol" "Midbody ring" "HPA023873: " "unprognostic (1.87e-1)" "unprognostic (3.61e-2)" "unprognostic (2.32e-1)" "unprognostic (3.03e-1)" "unprognostic (3.13e-1)" "unprognostic (2.74e-2)" "unprognostic (6.19e-3)" "unprognostic (2.99e-2)" "unprognostic (8.69e-3)" "unprognostic (1.25e-1)" "unprognostic (3.27e-2)" "unprognostic (2.93e-2)" "unprognostic (1.10e-2)" "unprognostic (3.05e-1)" "unprognostic (7.83e-2)" "unprognostic (4.96e-2)" "unprognostic (3.11e-2)" "unprognostic (1.43e-1)" "unprognostic (1.01e-1)" "unprognostic (2.63e-1)" "unprognostic (2.90e-1)" "unprognostic (2.45e-2)" "unprognostic (1.31e-2)" "unprognostic (2.20e-1)" "unprognostic (2.71e-2)" "unprognostic (3.15e-2)" "unprognostic (2.12e-1)" "unprognostic (3.23e-2)" "unprognostic (3.24e-1)" "unprognostic (2.06e-2)" "unprognostic (1.90e-1)" C9orf78 "CSU2, HCA59, HSPC220" ENSG00000136819 "Chromosome 9 open reading frame 78" Q9NZ63 9 129827290-129835863 "Predicted intracellular proteins" "Chromosome partition, mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epididymal clear cells: 338.9;Erythrocytes: 275.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021216, HPA021232, HPA021242" Enhanced Enhanced Nucleoplasm No No "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 9: T-cells - Adaptive immunity: Regulation" 21 Nucleoplasm "HPA021216: , HPA021232: , HPA021242: " "unprognostic (9.90e-2)" "unprognostic (1.14e-2)" "unprognostic (9.85e-2)" "unprognostic (1.29e-1)" "unprognostic (3.03e-2)" "potential prognostic unfavorable (5.97e-4)" "unprognostic (7.24e-2)" "unprognostic (4.79e-3)" "unprognostic (1.99e-1)" "unprognostic (9.04e-2)" "validated prognostic favorable (2.56e-4)" "validated prognostic favorable (9.57e-4)" "unprognostic (8.44e-3)" "unprognostic (6.78e-2)" "unprognostic (4.76e-2)" "unprognostic (9.34e-2)" "unprognostic (5.44e-2)" "unprognostic (1.41e-1)" "unprognostic (2.68e-2)" "unprognostic (2.16e-1)" "unprognostic (1.04e-1)" "unprognostic (1.52e-1)" "unprognostic (1.20e-1)" "unprognostic (1.43e-3)" "unprognostic (1.50e-1)" "unprognostic (3.29e-2)" "unprognostic (1.18e-1)" "unprognostic (5.61e-1)" "unprognostic (8.52e-3)" "unprognostic (1.51e-1)" "potential prognostic favorable (8.32e-4)" C9orf85 MGC61599 ENSG00000155621 "Chromosome 9 open reading frame 85" Q96MD7 9 71911510-71986054 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050767, HPA076627" Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus" No No "Cluster 3: Non-specific - Nuclear processes" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Transcription" "Golgi apparatus" "Nucleoplasm, Nucleoli" "HPA050767: , HPA076627: " "unprognostic (4.84e-2)" "unprognostic (3.31e-2)" "unprognostic (2.93e-3)" "unprognostic (4.30e-1)" "unprognostic (1.36e-1)" "unprognostic (1.25e-1)" "unprognostic (1.30e-1)" "potential prognostic favorable (5.72e-4)" "unprognostic (7.25e-2)" "unprognostic (4.49e-2)" "validated prognostic favorable (3.07e-4)" "validated prognostic favorable (4.95e-4)" "unprognostic (5.95e-2)" "potential prognostic unfavorable (1.75e-5)" "unprognostic (2.00e-2)" "unprognostic (1.77e-1)" "unprognostic (1.15e-1)" "unprognostic (8.31e-2)" "unprognostic (1.67e-1)" "unprognostic (2.57e-1)" "unprognostic (1.73e-1)" "unprognostic (3.76e-2)" "unprognostic (7.49e-2)" "unprognostic (2.42e-1)" "unprognostic (7.89e-3)" "unprognostic (1.55e-2)" "unprognostic (5.12e-2)" "unprognostic (8.54e-2)" "unprognostic (6.69e-2)" "unprognostic (2.46e-2)" "unprognostic (3.57e-1)" CA1 Car1 ENSG00000133742 "Carbonic anhydrase 1" P00915 8 85327608-85379014 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 63 "bone marrow: 1694.4;intestine: 1982.3" "Group enriched" "Detected in many" 7 "Colonocytes: 2197.3;Erythrocyte progenitors: 6551.1;Erythrocytes: 3490.6" "Cell type enhanced" "Detected in many" "LAMP5-LHX6 and Chandelier: 125.6" "Group enriched" "Detected in some" 5 "Colon Adenocarcinoma (TCGA): 15.1;Rectum Adenocarcinoma (TCGA): 38.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 32 "Leukemia: 111.9" "Colon - Colon enterocytes, Liver - Erythroid cells, Lung - Neutrophils_1, Pituitary gland - Neutrophils, Spleen - Erythrocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA006558, CAB025790" Enhanced NA NA 1600000000 "Cluster 11: Esophagus - Basic cellular processes" "Cluster 37: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 2 "CAB025790: , HPA006558: " "unprognostic (1.00e-1)" "unprognostic (1.18e-2)" "unprognostic (1.63e-1)" "unprognostic (2.50e-1)" "unprognostic (2.50e-1)" "unprognostic (8.67e-2)" "unprognostic (9.29e-2)" CA10 "CA-RPX, CARPX, HUCEP-15" ENSG00000154975 "Carbonic anhydrase 10" Q9NS85 17 51630313-52160017 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 120.4;retina: 41.2" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 744.3;Distal convoluted tubule cells: 406.8;Oligodendrocyte progenitor cells: 1923.7;Oocytes: 658.5;Pituitary stem cells: 301.7;Podocytes: 1028.5;Retinal bipolar cells: 3104.1" "Cell type enhanced" "Detected in all" "oligodendrocyte precursor cell: 2453.6;upper rhombic lip: 1773.4" "Group enriched" "Detected in some" 6 "Glioblastoma Multiforme (TCGA): 12.4;Kidney Chromophobe (TCGA): 10.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 2.3;thyroid cancer: 4.2" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Kidney - Podocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054825, HPA057837" Supported Approved Vesicles "Secreted in brain" "No annotated function" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 37: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 14 Vesicles "HPA054825: , HPA057837: " "unprognostic (1.53e-1)" "unprognostic (8.91e-3)" "unprognostic (1.54e-1)" "unprognostic (2.20e-2)" "unprognostic (6.74e-3)" "unprognostic (1.71e-1)" "unprognostic (3.52e-1)" CA11 "CARP2, CARPX1" ENSG00000063180 "Carbonic anhydrase 11" O75493 19 48637946-48646187 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 10 "brain: 517.6" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 85.8;Epididymal principal cells: 69.8;Hepatocytes: 58.2;Retinal amacrine cells: 49.9;Retinal bipolar cells: 57.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in many" 4 "Rhabdoid: 124.4" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041778 Approved Vesicles,Microtubules "Secreted in brain" "No annotated function" NA NA 75000 "Cluster 30: Non-specific - DNA binding" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 2 "Vesicles, Microtubules" "HPA041778: " "unprognostic (1.86e-1)" "unprognostic (2.41e-2)" "unprognostic (2.96e-1)" "unprognostic (2.93e-1)" "unprognostic (5.43e-3)" "unprognostic (8.85e-3)" "unprognostic (4.22e-2)" "unprognostic (1.58e-2)" "unprognostic (7.07e-2)" "unprognostic (1.29e-1)" "unprognostic (2.68e-1)" "unprognostic (7.71e-2)" "unprognostic (9.41e-2)" "unprognostic (1.79e-2)" "unprognostic (1.82e-1)" "unprognostic (1.71e-2)" "unprognostic (1.93e-1)" "unprognostic (8.51e-3)" "unprognostic (7.55e-3)" "unprognostic (5.16e-2)" "unprognostic (7.53e-2)" "potential prognostic favorable (1.14e-4)" "unprognostic (2.25e-1)" "unprognostic (2.88e-2)" "unprognostic (2.36e-2)" "unprognostic (2.42e-2)" "unprognostic (6.54e-3)" "unprognostic (1.74e-1)" "unprognostic (9.37e-2)" "unprognostic (2.28e-2)" "unprognostic (1.53e-1)" CA12 HsT18816 ENSG00000074410 "Carbonic anhydrase 12" O43570 15 63321378-63381846 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins" Lyase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 145.1;kidney: 271.0;skin 1: 134.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 429.0;Choroid plexus epithelial cells: 628.6;Colonocytes: 453.5;Conjunctival goblet cells: 405.8;Distal convoluted tubule cells: 1262.8;Epididymal efferent duct absorptive cells: 368.7;Esophageal basal cells: 377.9;Esophageal suprabasal cells: 378.5;Loop of henle epithelial cells: 441.2;Pancreatic acinar cells: 427.7;Pituicytes/FSCs: 455.8;Renal collecting duct intercalated cells: 2247.5;Renal connecting tubule cells: 749.4;Suprabasal keratinocytes: 504.6" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 419.9;medium spiny neuron: 120.1" "Cancer enriched" "Detected in all" 4 "Kidney Chromophobe (TCGA): 881.0" "Group enriched" "Detected in all" 5 "basal ganglia: 92.5;choroid plexus: 274.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 208.5" "Adipose subcutaneous - Adipose progenitor cells, Minor Salivary Gland - Minor salivary gland basal cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008773, CAB025181, CAB062549, CAB068179, HPA073203" Enhanced NA NA 24000 "Cluster 72: Kidney - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" "CAB025181: , CAB062549: , CAB068179: , HPA008773: , HPA073203: " "unprognostic (9.71e-2)" "unprognostic (1.10e-1)" "unprognostic (2.28e-1)" "unprognostic (3.60e-3)" "unprognostic (2.40e-2)" "unprognostic (2.81e-1)" "unprognostic (5.38e-2)" "unprognostic (1.41e-2)" "unprognostic (1.85e-2)" "unprognostic (3.92e-1)" "potential prognostic favorable (1.12e-4)" "unprognostic (1.65e-2)" "unprognostic (1.26e-1)" "unprognostic (7.88e-2)" "unprognostic (2.08e-3)" "unprognostic (3.29e-2)" "unprognostic (4.44e-2)" "unprognostic (9.61e-2)" "unprognostic (3.22e-2)" "unprognostic (2.03e-3)" "unprognostic (2.75e-1)" "potential prognostic unfavorable (1.26e-6)" "unprognostic (2.05e-1)" "unprognostic (2.37e-1)" "unprognostic (3.97e-1)" "potential prognostic unfavorable (3.36e-5)" "unprognostic (2.65e-1)" "unprognostic (1.51e-1)" "unprognostic (4.88e-2)" "unprognostic (1.27e-1)" "unprognostic (1.22e-1)" CA13 "CAXIII, FLJ37995, MGC59868" ENSG00000185015 "Carbonic anhydrase 13" Q8N1Q1 8 85220587-85284073 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 13.8" "Cell type enhanced" "Detected in many" "Enterocytes: 157.4" "Cell type enhanced" "Detected in all" "LAMP5-LHX6 and Chandelier: 129.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Urothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024689, CAB025567" Enhanced Approved Nucleoplasm,Nucleoli,Vesicles NA NA 170000 "Cluster 41: Basophils - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 1: Enterocytes - Absorption and Digestion" 1 Nucleoli "Nucleoplasm, Vesicles" "CAB025567: , HPA024689: " "unprognostic (1.40e-3)" "unprognostic (1.45e-2)" "unprognostic (5.14e-2)" "unprognostic (1.06e-2)" "unprognostic (7.52e-2)" "unprognostic (1.66e-3)" "unprognostic (6.00e-2)" "unprognostic (9.69e-2)" "unprognostic (6.65e-2)" "unprognostic (1.55e-2)" "unprognostic (6.77e-3)" "unprognostic (1.05e-1)" "unprognostic (1.70e-1)" "unprognostic (9.53e-2)" "unprognostic (1.18e-1)" "unprognostic (2.02e-2)" "unprognostic (6.94e-2)" "unprognostic (3.29e-1)" "unprognostic (7.01e-2)" "potential prognostic unfavorable (3.19e-4)" "unprognostic (1.06e-2)" "unprognostic (3.22e-1)" "unprognostic (2.53e-1)" "unprognostic (5.16e-2)" "unprognostic (7.39e-2)" "unprognostic (2.90e-1)" "unprognostic (8.08e-2)" "unprognostic (2.73e-2)" "unprognostic (1.36e-1)" "unprognostic (1.23e-1)" CA14 ENSG00000118298 "Carbonic anhydrase 14" Q9ULX7 1 150257251-150265078 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 43.3;choroid plexus: 112.9;retina: 36.5;tongue: 44.3" "Group enriched" "Detected in some" 6 "Melanocytes: 74.2;Müller glia: 170.1;Retinal pigment epithelial cells: 196.1" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 10.7;committed oligodendrocyte precursor: 11.3;oligodendrocyte: 27.6" "Cancer enriched" "Detected in many" 5 "Skin Cutaneous Melanoma (TCGA): 91.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 8 "Rhabdoid: 29.1;skin cancer: 20.9;testis cancer: 13.5" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Skin - Melanocytes, Testis - Peritubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008482 Approved Approved "Plasma membrane" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 11: Muller glia cells - Retinal homeostasis" 25 "Plasma membrane" "HPA008482: " "unprognostic (2.74e-2)" "unprognostic (2.78e-2)" "unprognostic (3.71e-2)" "unprognostic (3.62e-3)" "unprognostic (8.41e-3)" "unprognostic (3.79e-2)" "unprognostic (4.06e-3)" "unprognostic (9.38e-2)" "unprognostic (1.42e-1)" "unprognostic (1.70e-2)" "unprognostic (1.21e-1)" "unprognostic (4.29e-2)" "unprognostic (1.41e-1)" "unprognostic (2.03e-1)" "unprognostic (1.87e-1)" "unprognostic (6.40e-2)" "unprognostic (5.47e-2)" CA2 "CA-II, CAII, Car2" ENSG00000104267 "Carbonic anhydrase 2" P00918 8 85463968-85481493 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Lyase "Disease variant, FDA approved drug targets, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 944.3;intestine: 644.2;stomach 1: 1046.9" "Cell type enhanced" "Detected in many" "Colonocytes: 2144.8;Erythrocyte progenitors: 1624.1;Erythrocytes: 498.3;Extravillous trophoblasts: 681.2;Foveolar cells: 3491.7;Müller glia: 1234.5;Parietal cells: 809.7;Platelets: 722.8" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 468.9;oligodendrocyte: 412.5;pericyte: 293.5" "Cancer enriched" "Detected in all" 4 "Kidney Chromophobe (TCGA): 753.6" "Region enriched" "Detected in all" 5 "choroid plexus: 825.1" "Immune cell enhanced" "Detected in many" "basophil: 51.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Liver - Hepatocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Spleen - Erythrocytes, Stomach - Gastric mucous cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001550, CAB010102" Enhanced NA Yes 270000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 3 "CAB010102: , HPA001550: " "unprognostic (1.08e-3)" "unprognostic (1.04e-1)" "unprognostic (4.18e-2)" "unprognostic (9.23e-2)" "unprognostic (1.83e-2)" "unprognostic (1.13e-1)" "unprognostic (1.22e-1)" "unprognostic (9.13e-3)" "unprognostic (1.57e-1)" "unprognostic (1.58e-1)" "validated prognostic favorable (2.13e-8)" "validated prognostic favorable (4.11e-4)" "unprognostic (1.33e-3)" "unprognostic (1.88e-1)" "unprognostic (8.04e-3)" "unprognostic (1.07e-1)" "unprognostic (8.12e-2)" "unprognostic (1.53e-1)" "potential prognostic unfavorable (2.34e-4)" "unprognostic (1.62e-2)" "unprognostic (2.01e-1)" "unprognostic (1.49e-1)" "unprognostic (2.08e-3)" "unprognostic (1.25e-1)" "unprognostic (1.27e-1)" "unprognostic (8.48e-2)" "unprognostic (3.63e-1)" "unprognostic (2.63e-1)" "unprognostic (1.48e-1)" "unprognostic (1.09e-1)" "unprognostic (7.95e-2)" CA3 "CAIII, Car3" ENSG00000164879 "Carbonic anhydrase 3" P07451 8 85373436-85449040 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skeletal muscle: 4941.5" "Group enriched" "Detected in many" 5 "Myonuclei: 590.4;Thymic myoid cells: 908.2" "Cell type enhanced" "Detected in all" "LAMP5-LHX6 and Chandelier: 230.4" "Group enriched" "Detected in many" 7 "Glioblastoma Multiforme (TCGA): 53.6;Prostate Adenocarcinoma (TCGA): 17.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Kidney cancer: 6.7;Sarcoma: 6.5" "Prostate - Fibroblasts, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "medulla oblongata: 4.8" "CAB004967, HPA021775, HPA026700" Enhanced NA NA 30000000 "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 37: Neurons - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 2 "CAB004967: , HPA021775: , HPA026700: " "potential prognostic favorable (2.01e-4)" "unprognostic (1.41e-1)" "unprognostic (5.04e-2)" "unprognostic (1.81e-3)" "potential prognostic unfavorable (2.89e-4)" "unprognostic (2.15e-2)" "unprognostic (2.50e-3)" "unprognostic (1.11e-2)" "unprognostic (3.86e-2)" "unprognostic (5.45e-2)" "unprognostic (3.15e-2)" "unprognostic (3.91e-2)" "potential prognostic favorable (2.08e-4)" "unprognostic (1.07e-2)" "unprognostic (9.94e-2)" "unprognostic (2.98e-1)" "unprognostic (5.85e-2)" "unprognostic (3.04e-1)" "unprognostic (1.96e-1)" "unprognostic (6.09e-2)" "unprognostic (1.92e-1)" "unprognostic (6.27e-2)" "unprognostic (1.54e-1)" "unprognostic (1.12e-1)" "unprognostic (6.30e-2)" "unprognostic (1.42e-1)" "unprognostic (1.48e-1)" CA4 "CAIV, Car4, RP17" ENSG00000167434 "Carbonic anhydrase 4" P22748 17 60149942-60170899 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Lyase "Disease variant, FDA approved drug targets, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 247.2" "Cell type enriched" "Detected in many" 5 "Colonocytes: 1261.8" "Group enriched" "Detected in many" 4 "endothelial cell: 253.1;pericyte: 330.1;upper rhombic lip: 89.9" "Cancer enhanced" "Detected in many" "Rectum Adenocarcinoma (TCGA): 30.9" "Region enriched" "Detected in all" 5 "cerebellum: 173.8" "Immune cell enriched" "Detected in some" 7 "neutrophil: 100.0" "Lineage enriched" "Detected in single" 1000 "granulocytes: 100.0" "Cancer enhanced" "Detected in some" "Brain cancer: 4.3;liver cancer: 7.8;prostate cancer: 7.4" "Adipose visceral - Endothelial cells, Colon - Colon enterocytes, Spleen - Neutrophils_2" "Region enriched" "Detected in all" 5 "cerebellum: 300.3" "Low region specificity" "Detected in all" "HPA011089, HPA017258" Enhanced Uncertain Vesicles,Cytosol NA NA 210000 "Cluster 21: Neutrophils - Unknown function" "Cluster 17: Intestine - Digestion" "Cluster 35: Non-specific - DNA binding" "Cluster 1: Neuronal - Visual perception" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 4 Cytosol Vesicles "HPA011089: , HPA017258: " "unprognostic (4.04e-3)" "potential prognostic favorable (1.95e-4)" "unprognostic (3.16e-2)" "unprognostic (7.94e-2)" "unprognostic (2.74e-1)" "unprognostic (2.33e-1)" "unprognostic (5.41e-2)" "validated prognostic favorable (8.52e-7)" "validated prognostic favorable (2.35e-4)" "unprognostic (2.59e-1)" "unprognostic (5.35e-2)" "unprognostic (1.20e-3)" "unprognostic (1.00e-2)" "unprognostic (6.95e-2)" "unprognostic (2.71e-1)" "unprognostic (2.93e-2)" "unprognostic (2.16e-1)" "unprognostic (2.92e-2)" "unprognostic (1.00e-1)" "unprognostic (2.37e-1)" "unprognostic (3.67e-2)" "unprognostic (2.05e-1)" "unprognostic (2.45e-1)" "unprognostic (1.98e-2)" CA5A "CA5, CAV, CAVA" ENSG00000174990 "Carbonic anhydrase 5A" P35218 16 87881546-87936580 "Disease related genes, Enzymes, Essential proteins, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Lyase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 57 "liver: 30.1" "Group enriched" "Detected in some" 4 "Hepatocytes: 90.5;Oocytes: 27.6" "Cell type enriched" "Detected in many" 11 "endothelial cell: 19.7" "Cancer enriched" "Detected in single" 68 "Liver Hepatocellular Carcinoma (TCGA): 12.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 1.1;Gastric cancer: 1.6;liver cancer: 1.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 53: Liver - Plasma proteins" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 93: Hepatocytes - Bile production & excretion" "unprognostic (4.46e-3)" "unprognostic (2.03e-2)" CA5B ENSG00000169239 "Carbonic anhydrase 5B" Q9Y2D0 X 15688830-15788411 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Fibroblasts, Testis - Sertoli cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012618 Uncertain Supported Mitochondria NA NA "Cluster 1: T-cells - Unknown function" "Cluster 55: Breast - Lactation" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 27: Breast cancer - Unknown function" "Cluster 9: T-cells - Adaptive immunity: Regulation" 1 Mitochondria "HPA012618: " "unprognostic (7.42e-2)" "unprognostic (1.71e-3)" "unprognostic (2.74e-1)" "unprognostic (6.20e-2)" "unprognostic (2.88e-1)" "unprognostic (2.58e-2)" "unprognostic (4.81e-3)" "potential prognostic unfavorable (6.88e-4)" "unprognostic (9.42e-3)" "unprognostic (3.81e-2)" "potential prognostic favorable (1.60e-7)" "unprognostic (1.24e-3)" "unprognostic (3.75e-2)" "unprognostic (1.32e-1)" "unprognostic (2.21e-2)" "unprognostic (1.99e-3)" "unprognostic (2.17e-1)" "unprognostic (1.50e-1)" "unprognostic (2.94e-2)" "unprognostic (1.27e-2)" "unprognostic (1.74e-1)" "unprognostic (5.88e-2)" "unprognostic (3.04e-1)" "unprognostic (5.21e-1)" "unprognostic (1.81e-1)" "unprognostic (3.91e-3)" "unprognostic (4.05e-1)" "unprognostic (2.73e-1)" "unprognostic (1.84e-1)" "unprognostic (3.23e-2)" "unprognostic (4.28e-2)" CA6 ENSG00000131686 "Carbonic anhydrase 6" P23280 1 8945867-8975092 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted secreted proteins" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 290 "salivary gland: 8839.7" "Cell type enhanced" "Detected in some" "Breast lactating cells: 758.0;Neutrophils: 210.2;Salivary acinar cells: 4589.5;Salivary myoepithelial cells: 1427.8" "Cell type enriched" "Detected in single" 4 "leukocyte: 3.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "naive CD4 T-cell: 5.7;naive CD8 T-cell: 16.6" "Lineage enriched" "Detected in many" 12 "T-cells: 16.6" "Cancer enhanced" "Detected in some" "Gastric cancer: 4.3" "Breast - Breast glandular cells (progenitors)" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA028550, HPA028692" Enhanced "Secreted to digestive system" Enzyme NA NA 800000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 82: Salivary gland - Secretion" "Cluster 6: Non-specific - Immune response" "Cluster 70: DU4475 - Unknown function" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 35 "HPA028550: , HPA028692: " "unprognostic (8.10e-3)" "unprognostic (3.02e-1)" "unprognostic (1.87e-2)" "unprognostic (9.04e-2)" "unprognostic (4.33e-1)" "unprognostic (1.25e-1)" "unprognostic (1.47e-1)" "unprognostic (1.20e-1)" CA7 ENSG00000168748 "Carbonic anhydrase 7" P43166 16 66844414-66854153 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 53.4" "Cell type enhanced" "Detected in some" "Colonocytes: 504.1;Enteric transient amplifying cells: 40.2;Enterocytes: 103.6;Tuft cells: 311.3" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Rectum Adenocarcinoma (TCGA): 2.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enterocytes, Testis - Spermatogonia" "Region enhanced" "Detected in all" "cerebellum: 67.2" "Low region specificity" "Detected in many" HPA047237 Uncertain Approved "Golgi apparatus,Cytosol" NA NA "Cluster 17: Intestine - Digestion" "Cluster 51: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" Cytosol "Golgi apparatus" "HPA047237: " "unprognostic (1.00e-1)" "unprognostic (2.80e-2)" "unprognostic (2.16e-1)" "unprognostic (1.49e-2)" "unprognostic (1.06e-2)" CA8 "CALS, CARP" ENSG00000178538 "Carbonic anhydrase 8" P35219 8 60185412-60281400 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 13.9;parathyroid gland: 37.8" "Cell type enhanced" "Detected in many" "Corticotrophs: 432.3;Endometrial glandular cells: 175.0;Endometrial secretory cells: 224.0;Epididymal clear cells: 279.7;Oligodendrocyte progenitor cells: 215.0;Pituitary stem cells: 239.3;Renal collecting duct intercalated cells: 840.3;Sertoli cells: 501.2" "Cell type enhanced" "Detected in many" "LAMP5-LHX6 and Chandelier: 328.4;oligodendrocyte precursor cell: 227.0" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 8.9" "Region enhanced" "Detected in all" "cerebellum: 36.0" "Immune cell enriched" "Detected in some" 24 "basophil: 76.2" "Lineage enriched" "Detected in many" 24 "granulocytes: 76.2" "Cancer enhanced" "Detected in many" "skin cancer: 9.1" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Colon - Enteric glia cells, Heart muscle - Endothelial cells, Pituitary gland - Corticotropes, Prostate - Fibroblasts, Testis - Sertoli cells" "Region enriched" "Detected in all" 38 "cerebellum: 1260.6" "Region enriched" "Detected in all" 9 "cerebellum: 115.2" "HPA024748, CAB025545, CAB047309" Enhanced NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 35: Non-specific - DNA binding" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 12 "CAB025545: , CAB047309: , HPA024748: " "unprognostic (3.53e-1)" "unprognostic (3.95e-1)" "unprognostic (2.12e-2)" "unprognostic (1.26e-1)" "unprognostic (1.31e-1)" "unprognostic (1.80e-1)" "potential prognostic favorable (1.33e-4)" "unprognostic (4.24e-2)" "unprognostic (1.40e-1)" "unprognostic (2.35e-2)" "unprognostic (1.65e-1)" "unprognostic (1.03e-1)" "unprognostic (1.11e-1)" "unprognostic (2.35e-2)" "potential prognostic favorable (2.98e-5)" "unprognostic (1.61e-1)" "unprognostic (7.83e-3)" "unprognostic (1.72e-1)" "unprognostic (8.79e-3)" "unprognostic (8.76e-2)" "unprognostic (2.80e-1)" "unprognostic (2.42e-2)" CA9 "CAIX, MN" ENSG00000107159 "Carbonic anhydrase 9" Q16790 9 35673928-35681159 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "stomach 1: 293.9" "Cell type enhanced" "Detected in some" "Cholangiocytes: 54.5;Early spermatids: 334.7;Foveolar cells: 82.8;Gastric chief cells: 287.2;Late primary spermatocytes: 43.3;Mucous neck cells: 80.2;Pancreatic duct cells: 35.2;Parietal cells: 107.8" "Cell type enriched" "Detected in some" 11 "upper rhombic lip: 12.8" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 219.1" "Region enriched" "Detected in some" 9 "cerebellum: 11.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 114.9" "Adipose visceral - Mesothelial cells, Liver - Cholangiocytes, Prostate - Smooth muscle cells, Testis - Late spermatids" "Region enhanced" "Detected in many" "cerebellum: 12.3" "Low region specificity" "Detected in all" "CAB005100, CAB017107, HPA055207" Enhanced Supported "Plasma membrane" NA NA "Cluster 60: Stomach - Digestion" "Cluster 35: Non-specific - DNA binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 14 "Plasma membrane" "CAB005100: , CAB017107: , HPA055207: " "unprognostic (2.26e-2)" "unprognostic (3.73e-2)" "unprognostic (4.90e-1)" "potential prognostic unfavorable (9.05e-4)" "unprognostic (1.70e-1)" "unprognostic (1.22e-2)" "unprognostic (2.80e-3)" "unprognostic (2.67e-1)" "unprognostic (3.99e-2)" "potential prognostic favorable (5.22e-8)" "unprognostic (3.45e-2)" "unprognostic (1.28e-2)" "validated prognostic unfavorable (5.71e-6)" "validated prognostic unfavorable (7.41e-4)" "unprognostic (2.38e-3)" "potential prognostic unfavorable (4.33e-5)" "unprognostic (3.49e-1)" "unprognostic (1.64e-1)" "unprognostic (3.82e-1)" "unprognostic (2.79e-1)" "unprognostic (1.89e-3)" "unprognostic (5.25e-3)" "unprognostic (8.55e-2)" "unprognostic (1.34e-3)" "unprognostic (1.00e-1)" "unprognostic (6.38e-2)" "unprognostic (1.21e-1)" "unprognostic (1.29e-1)" CAAP1 "C9orf82, CAAP, FLJ13657" ENSG00000120159 "Caspase activity and apoptosis inhibitor 1" Q9H8G2 9 26840685-26892803 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Choroid plexus epithelial cells: 229.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020404, HPA024029, HPA024100" Uncertain Approved Vesicles NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 76: Non-specific - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 10 Vesicles "HPA020404: , HPA024029: , HPA024100: " "unprognostic (8.46e-3)" "unprognostic (2.62e-1)" "unprognostic (6.95e-2)" "unprognostic (7.55e-2)" "unprognostic (2.18e-1)" "unprognostic (7.73e-2)" "unprognostic (2.20e-1)" "unprognostic (2.90e-2)" "unprognostic (7.65e-2)" "potential prognostic favorable (2.93e-8)" "unprognostic (3.26e-3)" "unprognostic (1.11e-1)" "unprognostic (8.44e-2)" "unprognostic (1.04e-1)" "unprognostic (5.87e-2)" "unprognostic (3.84e-2)" "unprognostic (3.23e-1)" "unprognostic (4.09e-3)" "unprognostic (2.50e-1)" "unprognostic (1.53e-1)" "unprognostic (7.11e-2)" "unprognostic (1.17e-1)" "potential prognostic favorable (7.04e-4)" "unprognostic (6.09e-3)" "unprognostic (7.17e-3)" "unprognostic (9.46e-2)" "unprognostic (1.64e-1)" "unprognostic (5.18e-2)" "unprognostic (4.43e-2)" CAB39 "CGI-66, MO25" ENSG00000135932 "Calcium binding protein 39" Q9Y376 2 230712842-230821075 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 168.0" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 720.1;Neutrophils: 1324.0;Urothelial cells: 540.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037112, HPA076632" Approved Approved "Endoplasmic reticulum,Vesicles" NA NA 85000 "Cluster 35: Neutrophils - Protein binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 21 Vesicles "Endoplasmic reticulum" "CAB037112: , HPA076632: " "unprognostic (1.19e-1)" "unprognostic (1.59e-2)" "unprognostic (2.58e-1)" "unprognostic (6.43e-2)" "unprognostic (1.33e-1)" "unprognostic (8.20e-2)" "unprognostic (3.46e-1)" "unprognostic (4.12e-2)" "unprognostic (2.05e-1)" "unprognostic (2.92e-1)" "potential prognostic favorable (2.27e-6)" "unprognostic (5.89e-3)" "unprognostic (2.94e-1)" "unprognostic (4.28e-2)" "unprognostic (1.11e-2)" "unprognostic (1.02e-1)" "unprognostic (3.51e-2)" "unprognostic (2.05e-2)" "unprognostic (1.25e-1)" "unprognostic (1.86e-3)" "unprognostic (6.08e-3)" "potential prognostic unfavorable (1.18e-4)" "unprognostic (8.83e-2)" "unprognostic (2.28e-1)" "unprognostic (1.10e-1)" "unprognostic (3.76e-2)" "unprognostic (1.08e-1)" "unprognostic (1.08e-1)" "unprognostic (3.36e-2)" "unprognostic (2.09e-1)" "unprognostic (1.15e-1)" CAB39L "bA103J18.3, FLJ12577, MO2L" ENSG00000102547 "Calcium binding protein 39 like" Q9H9S4 13 49308650-49444064 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 88.0" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 585.3;Early spermatids: 299.3;Fibro-adipogenic progenitors: 206.5;Late primary spermatocytes: 211.1;Prostatic glandular cells: 296.6;Schwann cells: 297.4" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 466.9" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 60.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "prostate cancer: 33.2" "Lung - Fibroblasts_1, Prostate - Prostate glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003686, HPA045954, HPA076632" Approved Approved Vesicles NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 3: Choroid plexus - Cilium" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 6 Vesicles "CAB003686: , HPA045954: , HPA076632: " "unprognostic (6.60e-3)" "unprognostic (2.98e-3)" "unprognostic (2.53e-2)" "unprognostic (4.21e-2)" "unprognostic (1.89e-1)" "unprognostic (1.51e-2)" "unprognostic (9.02e-2)" "unprognostic (2.55e-1)" "unprognostic (7.71e-2)" "unprognostic (6.19e-2)" "potential prognostic favorable (4.76e-10)" "unprognostic (1.08e-3)" "unprognostic (3.08e-3)" "unprognostic (1.52e-1)" "unprognostic (1.31e-1)" "unprognostic (3.80e-2)" "unprognostic (7.97e-2)" "unprognostic (5.91e-2)" "unprognostic (5.09e-2)" "potential prognostic unfavorable (2.75e-4)" "unprognostic (3.09e-2)" "unprognostic (7.58e-2)" "unprognostic (4.78e-1)" "unprognostic (8.89e-3)" "unprognostic (1.10e-1)" "unprognostic (1.49e-1)" "unprognostic (6.22e-2)" "unprognostic (7.47e-2)" "unprognostic (1.33e-1)" "unprognostic (3.64e-2)" "unprognostic (7.45e-2)" CABCOCO1 "bA63A2.1, C10orf107, Em:AC022398.2, MGC44593" ENSG00000183346 "Ciliary associated calcium binding coiled-coil 1" Q8IVU9 10 61662929-61766766 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 13.6;fallopian tube: 25.1;testis: 14.4" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 118.6;Ependymal cells: 398.7;Epididymal efferent duct ciliated cells: 299.2;Fallopian tube ciliated cells: 322.3;Late primary spermatocytes: 159.4;Respiratory ciliated cells: 486.0;Thyrotrophs: 81.4" "Cell type enriched" "Detected in many" 6 "ependymal cell: 445.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA041398 Enhanced Approved "Nucleoplasm,Centrosome,Basal body,Cytosol" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 34: Ciliated cells - Cilia assembly & function" 20 "Centrosome, Basal body" "Nucleoplasm, Cytosol" "HPA041398: " "unprognostic (9.96e-3)" "unprognostic (4.72e-3)" "unprognostic (4.41e-3)" "unprognostic (1.79e-2)" "unprognostic (4.65e-2)" "unprognostic (2.36e-2)" "unprognostic (3.95e-2)" "unprognostic (3.35e-1)" "unprognostic (7.67e-2)" "unprognostic (3.57e-1)" "unprognostic (1.75e-1)" "unprognostic (2.29e-2)" "unprognostic (4.78e-2)" "unprognostic (4.79e-2)" CABIN1 "KIAA0330, PPP3IN" ENSG00000099991 "Calcineurin binding protein 1" Q9Y6J0 22 24011192-24178628 "Plasma proteins, Predicted intracellular proteins" "Chromatin regulator" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043296 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 7: Non-specific - Transcription" 24 "Nucleoplasm, Cytosol" "HPA043296: " "unprognostic (1.92e-1)" "unprognostic (1.14e-1)" "unprognostic (1.59e-2)" "unprognostic (3.15e-1)" "unprognostic (1.17e-2)" "unprognostic (1.22e-2)" "unprognostic (1.41e-1)" "unprognostic (1.96e-1)" "unprognostic (8.67e-2)" "unprognostic (1.70e-3)" "unprognostic (1.63e-2)" "unprognostic (3.50e-2)" "potential prognostic favorable (9.66e-4)" "unprognostic (5.84e-3)" "unprognostic (3.50e-1)" "unprognostic (1.01e-2)" "unprognostic (8.57e-2)" "unprognostic (1.03e-2)" "unprognostic (2.50e-3)" "unprognostic (2.80e-1)" "unprognostic (1.33e-1)" "potential prognostic favorable (8.64e-4)" "unprognostic (1.88e-2)" "unprognostic (1.67e-1)" "unprognostic (2.23e-1)" "potential prognostic favorable (6.71e-4)" "unprognostic (3.91e-2)" "unprognostic (1.64e-1)" "unprognostic (1.66e-1)" "unprognostic (2.95e-2)" "potential prognostic favorable (7.72e-4)" CABLES1 "FLJ35924, HsT2563" ENSG00000134508 "Cdk5 and Abl enzyme substrate 1" Q8TDN4 18 23134564-23260470 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" Cyclin "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 53.3" "Cell type enhanced" "Detected in many" "Astrocytes: 533.9;Bergmann glia: 481.9;Endometrial glandular cells: 1282.4;Endometrial luminal cells: 366.7;Hofbauer cells: 242.9;Melanocytes: 355.7" "Cell type enhanced" "Detected in all" "astrocyte: 528.5;Bergmann glia: 442.8" "Cancer enriched" "Detected in all" 5 "Skin Cutaneous Melanoma (TCGA): 99.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "NK-cell: 1.2" "Lineage enriched" "Detected in single" 8 "NK-cells: 1.2" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Prostate - Fibroblasts, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073649 Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 78: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 51: Secretory epithelial cells - Mixed function" 4 "Nucleoplasm, Nuclear bodies" "HPA073649: " "unprognostic (3.20e-1)" "unprognostic (8.73e-2)" "unprognostic (1.63e-1)" "unprognostic (2.57e-1)" "unprognostic (3.59e-2)" "potential prognostic unfavorable (5.86e-4)" "unprognostic (1.73e-1)" "potential prognostic favorable (1.37e-6)" "unprognostic (1.03e-3)" "unprognostic (3.59e-2)" "validated prognostic favorable (6.02e-11)" "validated prognostic favorable (3.72e-5)" "unprognostic (5.09e-3)" "unprognostic (1.93e-3)" "unprognostic (2.57e-2)" "unprognostic (1.01e-2)" "unprognostic (6.24e-3)" "unprognostic (1.14e-1)" "unprognostic (1.15e-1)" "unprognostic (6.39e-2)" "unprognostic (2.95e-1)" "unprognostic (4.02e-2)" "unprognostic (1.95e-1)" "unprognostic (1.82e-2)" "unprognostic (2.95e-1)" "unprognostic (4.78e-2)" "unprognostic (1.59e-1)" "unprognostic (1.92e-1)" "unprognostic (4.66e-2)" "unprognostic (7.82e-2)" "unprognostic (3.86e-2)" CABLES2 "C20orf150, dJ908M14.2, ik3-2" ENSG00000149679 "Cdk5 and Abl enzyme substrate 2" Q9BTV7 20 62388634-62407285 "Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division" Cyclin "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 29.4" "Cell type enhanced" "Detected in many" "Early spermatids: 32.7;Late primary spermatocytes: 59.1;Late spermatids: 38.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043597 Approved Nucleoli NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 67: Testis - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" 2 Nucleoli "HPA043597: " "unprognostic (4.16e-2)" "unprognostic (1.59e-2)" "unprognostic (5.29e-2)" "unprognostic (2.34e-1)" "unprognostic (1.80e-1)" "unprognostic (2.63e-1)" "unprognostic (3.32e-2)" "unprognostic (1.07e-2)" "unprognostic (2.79e-2)" "potential prognostic unfavorable (9.87e-5)" "unprognostic (4.86e-3)" "unprognostic (1.85e-2)" "unprognostic (9.26e-3)" "unprognostic (1.83e-2)" "potential prognostic unfavorable (3.46e-4)" "unprognostic (1.07e-1)" "unprognostic (4.57e-2)" "unprognostic (6.55e-2)" "unprognostic (3.89e-2)" "unprognostic (3.68e-1)" "unprognostic (1.98e-1)" "unprognostic (1.16e-2)" "potential prognostic unfavorable (2.63e-4)" "unprognostic (1.06e-1)" "unprognostic (1.08e-2)" "unprognostic (2.00e-1)" "unprognostic (1.20e-1)" "unprognostic (8.82e-3)" "unprognostic (1.18e-1)" "unprognostic (3.56e-2)" "unprognostic (6.79e-2)" CABP1 ENSG00000157782 "Calcium binding protein 1" Q9NZU7 12 120640626-120667324 "Predicted intracellular proteins, Transporters" "Sensory transduction, Vision" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 18 "brain: 419.6" "Group enriched" "Detected in many" 4 "Brain excitatory neurons: 156.1;Retinal amacrine cells: 258.6;Retinal bipolar cells: 148.5;Retinal ganglion cells: 197.0;Retinal horizontal cells: 522.9" "Cell type enhanced" "Detected in many" "hippocampal CA1-3: 399.7" "Group enriched" "Detected in many" 4 "Glioblastoma Multiforme (TCGA): 8.0;Kidney Renal Clear Cell Carcinoma (TCGA): 15.9;Kidney Renal Papillary Cell Carcinoma (TCGA): 18.6" "Region enhanced" "Detected in all" "cerebral cortex: 514.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 25 "Rhabdoid: 61.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 238.6" HPA051438 Uncertain NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" 5 "HPA051438: " "unprognostic (3.28e-3)" "unprognostic (1.83e-2)" "unprognostic (5.37e-3)" "unprognostic (5.60e-2)" "unprognostic (5.71e-3)" "unprognostic (5.52e-3)" "potential prognostic favorable (1.50e-4)" "unprognostic (1.25e-2)" "potential prognostic favorable (9.83e-8)" "unprognostic (3.84e-1)" "unprognostic (7.83e-3)" "unprognostic (1.69e-1)" "unprognostic (1.10e-1)" "unprognostic (2.84e-1)" "unprognostic (1.24e-1)" "unprognostic (2.14e-2)" CABP2 DFNB93 ENSG00000167791 "Calcium binding protein 2" Q9NPB3 11 67518912-67524517 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Hearing, Sensory transduction, Vision" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 9 "retina: 6.8" "Cell type enriched" "Detected in some" 36 "Retinal bipolar cells: 72.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 22 "cerebellum: 9.3" "Not detected" "Not detected" NA NA "Cluster 42: Retina - Visual perception" "Cluster 1: Neuronal - Visual perception" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 27 CABP4 CSNB2B ENSG00000175544 "Calcium binding protein 4" P57796 11 67452406-67461752 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "retina: 63.1" "Group enriched" "Detected in many" 4 "Cone photoreceptor cells: 147.0;Rod photoreceptor cells: 213.2" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 7.7;endothelial cell: 3.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "non-classical monocyte: 12.1" "Lineage enriched" "Detected in many" 6 "monocytes: 12.1" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 4.1" "Adipose subcutaneous - Macrophages, Breast - Breast glandular cells, Liver - Kupffer cells, Spleen - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in single" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 42: Retina - Visual perception" "Cluster 6: Non-specific - Immune response" "Cluster 70: DU4475 - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" "unprognostic (9.20e-3)" "unprognostic (1.60e-1)" "unprognostic (8.24e-2)" "unprognostic (9.56e-3)" "unprognostic (3.63e-1)" "unprognostic (9.97e-2)" "unprognostic (1.68e-2)" "unprognostic (4.81e-3)" "unprognostic (1.13e-2)" "unprognostic (1.50e-1)" "unprognostic (1.31e-1)" "unprognostic (5.74e-3)" "unprognostic (6.45e-2)" "unprognostic (2.21e-3)" "unprognostic (1.06e-3)" "unprognostic (2.96e-1)" "unprognostic (1.04e-1)" "unprognostic (5.76e-2)" "unprognostic (4.47e-2)" "unprognostic (5.75e-2)" CABP5 CABP3 ENSG00000105507 "Calcium binding protein 5" Q9NP86 19 48029383-48044079 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 917 "retina: 360.1" "Group enriched" "Detected in some" 10 "Retinal bipolar cells: 325.5;Rod photoreceptor cells: 654.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 1.5" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.5" "Cancer enhanced" "Detected in single" "Uterine cancer: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA043698 Enhanced NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 42: Retina - Visual perception" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 1: Neuronal - Visual perception" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 37 "HPA043698: " CABP7 MGC57793 ENSG00000100314 "Calcium binding protein 7" Q86V35 22 29720003-29731833 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "brain: 52.8" "Cell type enhanced" "Detected in some" "Adrenal cortex cells: 3.5;Brain excitatory neurons: 5.0;Cardiomyocytes: 7.4;Epicardial cells: 4.5;Epididymal efferent duct ciliated cells: 18.5;Oligodendrocyte progenitor cells: 2.8;Other brain neurons: 5.4;Pancreatic islet cells: 10.2;Paneth cells: 3.9;Schwann cells: 6.3" "Cell type enhanced" "Detected in many" "deep-layer corticothalamic and 6b: 15.9;hippocampal CA1-3: 15.4;lower rhombic lip: 14.7" "Cancer enhanced" "Detected in many" "Pancreatic Adenocarcinoma (TCGA): 5.5;Uterine Corpus Endometrial Carcinoma (TCGA): 4.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 5.8" "Adrenal gland - Adrenal cortex cells, Pancreas - Beta cells" "Group enriched" "Detected in all" 4 "cerebellum: 74.4;hippocampal formation: 205.0;midbrain: 60.3;pons and medulla: 110.0" "Region enhanced" "Detected in all" "hippocampal formation: 77.5" HPA016439 Uncertain NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 43: Hindbrain - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 1 "HPA016439: " "unprognostic (6.22e-2)" "unprognostic (1.49e-1)" "unprognostic (2.46e-1)" "unprognostic (6.80e-2)" "unprognostic (3.48e-2)" "unprognostic (3.35e-1)" "unprognostic (3.00e-2)" "unprognostic (2.70e-1)" "unprognostic (4.87e-2)" "unprognostic (1.72e-2)" "unprognostic (5.30e-2)" CABS1 "C4orf35, CLPH, FLJ32897, NYD-SP26" ENSG00000145309 "Calcium binding protein, spermatid associated 1" Q96KC9 4 70334981-70337116 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "testis: 101.9" "Cell type enriched" "Detected in some" 5 "Late spermatids: 8200.5" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "midbrain: 1.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA044016, HPA055352" Enhanced NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 46: Brainstem - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 3 "HPA044016: , HPA055352: " CABYR "CBP86, CT88, FSP-2" ENSG00000154040 "Calcium binding tyrosine phosphorylation regulated" O75952 18 24138987-24161600 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 23 "testis: 287.9" "Group enriched" "Detected in many" 4 "Early spermatids: 2840.6;Late spermatids: 5981.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 34.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 5.6;memory B-cell: 4.8;naive B-cell: 5.4;neutrophil: 2.0" "Group enriched" "Detected in many" 6 "B-cells: 5.4;granulocytes: 5.6" "Cancer enriched" "Detected in many" 5 "Gallbladder cancer: 102.6" "Skin - Outer root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA040703, HPA047801" Enhanced Supported "Nucleoplasm,Cytosol,Principal piece" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 6: Testis - Spermatogenesis" "Cluster 53: Neurons - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 2 "Nucleoplasm, Cytosol, Principal piece" "HPA040703: , HPA047801: " "unprognostic (4.12e-2)" "unprognostic (4.82e-3)" "unprognostic (1.66e-1)" "unprognostic (7.58e-3)" "unprognostic (1.82e-1)" "unprognostic (8.00e-3)" "unprognostic (4.24e-2)" "unprognostic (3.84e-2)" "unprognostic (4.15e-2)" "potential prognostic unfavorable (9.09e-4)" "potential prognostic unfavorable (1.86e-6)" "unprognostic (1.50e-2)" "unprognostic (4.18e-2)" "potential prognostic unfavorable (4.26e-4)" "unprognostic (6.12e-2)" "unprognostic (5.05e-2)" "unprognostic (1.76e-1)" "unprognostic (3.59e-1)" "unprognostic (1.20e-2)" "unprognostic (1.16e-2)" "unprognostic (5.30e-1)" "unprognostic (3.18e-2)" "unprognostic (1.14e-1)" "unprognostic (1.58e-1)" "unprognostic (2.78e-1)" "unprognostic (8.12e-2)" "unprognostic (2.53e-1)" "unprognostic (4.86e-2)" "unprognostic (1.54e-1)" "unprognostic (2.70e-1)" "unprognostic (2.15e-1)" CACFD1 "C9orf7, D9S2135, flower" ENSG00000160325 "Calcium channel flower domain containing 1" Q9UGQ2 9 133459965-133470848 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 56.6" "Cell type enhanced" "Detected in some" "Astrocytes: 7.9;Bergmann glia: 5.9;Brain excitatory neurons: 6.0;Brain inhibitory neurons: 5.9;Choroid plexus epithelial cells: 7.2;Distal convoluted tubule cells: 7.5;Ependymal cells: 7.8;Loop of henle epithelial cells: 8.6;Oligodendrocyte progenitor cells: 8.7;Oligodendrocytes: 7.4;Other brain neurons: 6.9;Papillary tip epithelial cells: 8.6;Podocytes: 7.7;Proximal tubule cells: 11.6;Renal collecting duct intercalated cells: 7.9;Renal collecting duct principal cells: 7.8;Renal connecting tubule cells: 9.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.8" "Group enriched" "Detected in many" 4 "B-cells: 2.0;granulocytes: 3.8" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015280 Approved Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 70: Non-specific - Protein processing" "Cluster 6: Non-specific - Immune response" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 98: Neurons - Neurotransmission & signaling" 7 Nucleoplasm "HPA015280: " "unprognostic (2.01e-2)" "unprognostic (1.25e-1)" "unprognostic (6.06e-2)" "unprognostic (6.15e-2)" "unprognostic (1.03e-1)" "unprognostic (3.74e-1)" "unprognostic (1.03e-2)" "unprognostic (1.05e-1)" "unprognostic (3.28e-2)" "validated prognostic favorable (9.02e-4)" "validated prognostic favorable (9.89e-4)" "unprognostic (1.91e-2)" "unprognostic (5.51e-3)" "unprognostic (8.49e-3)" "unprognostic (1.18e-1)" "unprognostic (1.65e-1)" "unprognostic (1.80e-1)" "unprognostic (1.53e-1)" "unprognostic (4.69e-2)" "unprognostic (3.11e-1)" "unprognostic (7.74e-2)" "unprognostic (6.00e-2)" "unprognostic (8.27e-2)" "unprognostic (4.29e-2)" "unprognostic (9.92e-2)" "unprognostic (2.73e-1)" "unprognostic (9.38e-3)" "unprognostic (4.97e-2)" "unprognostic (1.05e-1)" CACHD1 "KIAA1573, VWCD1" ENSG00000158966 "Cache domain containing 1" Q5VU97 1 64470129-64693058 "Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 436.6;Astrocytes: 546.1;Bergmann glia: 601.9;Choroid plexus epithelial cells: 602.9;Ependymal cells: 396.3;Medullary thymic epithelial cells: 350.4;Mesothelial cells: 336.2;Pituicytes/FSCs: 417.1" "Cell type enhanced" "Detected in all" "astrocyte: 655.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 32.6" "Pituitary gland - Undifferentiated cells (Pituitary gland)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017202 Uncertain Uncertain Nucleoplasm,Nucleoli NA NA 240000 "Cluster 65: Brain - Transcription" "Cluster 33: Neurons - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 6 "Nucleoplasm, Nucleoli" "HPA017202: " "unprognostic (9.25e-2)" "unprognostic (1.99e-2)" "unprognostic (1.83e-1)" "unprognostic (1.39e-1)" "unprognostic (5.37e-2)" "unprognostic (5.51e-3)" "unprognostic (3.79e-1)" "unprognostic (2.58e-2)" "unprognostic (1.67e-1)" "unprognostic (7.43e-2)" "potential prognostic favorable (1.49e-5)" "unprognostic (1.65e-2)" "unprognostic (1.49e-3)" "unprognostic (6.76e-2)" "unprognostic (2.64e-1)" "unprognostic (2.47e-2)" "unprognostic (4.19e-1)" "unprognostic (1.50e-1)" "unprognostic (1.90e-2)" "unprognostic (5.86e-2)" "unprognostic (1.25e-1)" "unprognostic (1.79e-1)" "unprognostic (9.81e-2)" "unprognostic (7.82e-2)" "unprognostic (1.17e-2)" "unprognostic (1.42e-1)" "unprognostic (3.51e-1)" "unprognostic (2.47e-2)" "unprognostic (2.03e-1)" "unprognostic (1.94e-1)" "unprognostic (1.43e-1)" CACNA1A "APCA, CACNL1A4, Cav2.1, EA2, FHM, HPCA, MHP, MHP1, SCA6" ENSG00000141837 "Calcium voltage-gated channel subunit alpha1 A" O00555 19 13206442-13633025 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 43 "brain: 286.3" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 457.4;Brain excitatory neurons: 662.9;Brain inhibitory neurons: 570.0;Neuroendocrine cells: 1660.7;Oligodendrocyte progenitor cells: 736.9;Other brain neurons: 289.5;Pancreatic islet cells: 858.9;Pituitary stem cells: 619.2;Retinal amacrine cells: 1020.0;Retinal ganglion cells: 544.7;Retinal horizontal cells: 1336.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 6.5" "Region enhanced" "Detected in all" "cerebellum: 218.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 5.2;lung cancer: 8.4;Rhabdoid: 8.2" "Adrenal gland - Adrenal medulla cells, Pancreas - Alpha cells, Skeletal muscle - Smooth muscle cells, Stomach - Gastric enteroendocrine cells, Testis - Early spermatids, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064258, HPA068138, HPA071902" Enhanced Supported Uncertain "Endoplasmic reticulum" NA NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 2: Neurons - Nucleosome" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" 41 "Endoplasmic reticulum" "HPA064258: , HPA068138: , HPA071902: " "unprognostic (6.25e-2)" "unprognostic (1.87e-2)" "unprognostic (8.10e-2)" "potential prognostic favorable (2.58e-4)" "unprognostic (1.10e-2)" "unprognostic (6.23e-2)" "potential prognostic favorable (8.21e-6)" "unprognostic (2.93e-2)" "unprognostic (1.60e-1)" "unprognostic (2.70e-1)" "unprognostic (2.50e-1)" "unprognostic (5.19e-2)" CACNA1B "CACNL1A5, CACNN, Cav2.2" ENSG00000148408 "Calcium voltage-gated channel subunit alpha1 B" Q00975 9 137877782-138124624 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 23.4;pituitary gland: 6.5" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 319.1;Brain excitatory neurons: 493.2;Brain inhibitory neurons: 541.2;Early primary spermatocytes: 154.5;Gonadotrophs: 248.0;Lactotrophs: 262.2;Other brain neurons: 515.8;Retinal amacrine cells: 584.2;Retinal ganglion cells: 641.2;Somatotrophs: 459.6;Thyrotrophs: 438.9" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 4.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 14.3" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044347 Uncertain Approved "Cytosol,Acrosome,Equatorial segment" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 53: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 3 "Cytosol, Acrosome, Equatorial segment" "HPA044347: " "unprognostic (4.29e-2)" "unprognostic (5.93e-3)" "unprognostic (1.08e-2)" "unprognostic (1.83e-2)" "unprognostic (1.50e-2)" "unprognostic (1.57e-1)" CACNA1C "CACH2, CACN2, CACNL1A1, Cav1.2, CCHL1A1, LQT8, TS" ENSG00000151067 "Calcium voltage-gated channel subunit alpha1 C" Q13936 12 1970772-2697950 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Host-virus interaction, Ion transport, Transport" "Calcium channel, Calmodulin-binding, Ion channel, Voltage-gated channel" "Autism, Autism spectrum disorder, Brugada syndrome, Disease variant, Epilepsy, FDA approved drug targets, Intellectual disability, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 25.0" "Cell type enhanced" "Detected in some" "Astrocytes: 180.2;Bergmann glia: 163.4;Brain excitatory neurons: 661.1;Brain inhibitory neurons: 711.5;Choroid plexus epithelial cells: 147.0;Oligodendrocyte progenitor cells: 284.3;Other brain neurons: 504.7;Pericytes: 220.8;Vascular smooth muscle cells: 464.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 3.9" "Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039796, CAB079031" Enhanced Approved Approved "Nucleoplasm,Plasma membrane,Primary cilium" NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 105: Non-specific - Mixed function" 27 "Nucleoplasm, Plasma membrane" "Primary cilium" "CAB079031: , HPA039796: " "unprognostic (3.73e-2)" "unprognostic (9.56e-2)" "unprognostic (7.20e-2)" "unprognostic (8.22e-2)" "unprognostic (1.22e-3)" "validated prognostic favorable (1.04e-4)" "validated prognostic favorable (4.50e-4)" "unprognostic (3.90e-1)" "unprognostic (2.10e-2)" "unprognostic (1.43e-2)" "unprognostic (2.39e-1)" "unprognostic (6.39e-2)" "unprognostic (8.77e-3)" "unprognostic (2.07e-2)" "unprognostic (1.10e-1)" CACNA1D "CACH3, CACN4, CACNL1A2, Cav1.3, CCHL1A2" ENSG00000157388 "Calcium voltage-gated channel subunit alpha1 D" Q01668 3 53328963-53813733 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Cancer-related genes, Deafness, Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 859.0;Adrenal medulla cells: 574.4;Brain inhibitory neurons: 485.7;Corticotrophs: 671.0;Distal convoluted tubule cells: 583.3;Lactotrophs: 420.6;Microglia: 398.6;Pancreatic islet cells: 487.9;Retinal amacrine cells: 727.2;Retinal pigment epithelial cells: 716.2;Somatotrophs: 602.0;Thyrotrophs: 1007.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "basophil: 3.7" "Lineage enriched" "Detected in single" 20 "granulocytes: 3.7" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Skeletal muscle - Fibroblasts, Testis - Peritubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020215 Uncertain Approved "Nuclear membrane" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 22: Epididymis - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 50: Lymphoma - Unknown function" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" "Nuclear membrane" "HPA020215: " "unprognostic (1.70e-1)" "unprognostic (1.15e-1)" "unprognostic (2.50e-2)" "unprognostic (3.32e-2)" "unprognostic (8.32e-2)" "unprognostic (7.08e-3)" "unprognostic (2.66e-1)" "potential prognostic favorable (1.69e-8)" "unprognostic (3.49e-3)" "unprognostic (1.34e-2)" "unprognostic (1.57e-1)" "unprognostic (2.53e-3)" "unprognostic (6.70e-2)" "unprognostic (7.68e-2)" "unprognostic (1.19e-1)" "unprognostic (2.15e-1)" "unprognostic (1.06e-2)" "unprognostic (1.29e-2)" "unprognostic (2.74e-1)" "unprognostic (5.70e-2)" CACNA1E "BII, CACH6, CACNL1A6, Cav2.3" ENSG00000198216 "Calcium voltage-gated channel subunit alpha1 E" Q15878 1 181317690-181813262 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "brain: 16.6" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 265.9;Bergmann glia: 261.9;Brain excitatory neurons: 434.0;Brain inhibitory neurons: 486.0;Neutrophils: 122.9;Oligodendrocyte progenitor cells: 119.5;Other brain neurons: 270.9;Proximal tubule cells: 248.2;Retinal amacrine cells: 202.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 2.4;lung cancer: 2.0" "Adipose visceral - Neutrophils, Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Kidney - Proximal tubular cells, Lung - Neutrophils_2, Spleen - Neutrophils_2, Stomach - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042515, CAB079032" Approved Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 35: Neurons - Synaptic function & neurogenesis" "Plasma membrane" "Actin filaments, Cytosol" "CAB079032: , HPA042515: " "unprognostic (3.10e-1)" "potential prognostic favorable (5.61e-5)" "unprognostic (1.36e-2)" "unprognostic (8.10e-3)" "unprognostic (8.88e-3)" "unprognostic (1.22e-1)" "unprognostic (3.72e-2)" "unprognostic (3.23e-2)" CACNA1F "AIED, Cav1.4, CORDX3, CSNB2, CSNB2A, CSNBX2, JM8, JMC8, OA2" ENSG00000102001 "Calcium voltage-gated channel subunit alpha1 F" O60840 X 49205063-49233371 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Sensory transduction, Transport, Vision" "Calcium channel, Ion channel, Voltage-gated channel" "Cone-rod dystrophy, Congenital stationary night blindness, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 61 "retina: 116.2" "Group enriched" "Detected in some" 6 "Cone photoreceptor cells: 130.4;Retinal bipolar cells: 175.8;Rod photoreceptor cells: 217.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in single" "Breast - Breast glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA068379 Enhanced NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 42: Retina - Visual perception" "Cluster 48: Non-specific - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "HPA068379: " "unprognostic (3.99e-2)" "unprognostic (8.06e-2)" "unprognostic (1.02e-2)" "unprognostic (3.60e-2)" "unprognostic (3.59e-1)" "unprognostic (2.01e-2)" "unprognostic (1.82e-1)" CACNA1G "Cav3.1, NBR13" ENSG00000006283 "Calcium voltage-gated channel subunit alpha1 G" O43497 17 50560715-50627474 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, FDA approved drug targets, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 19.3;cervix: 8.2;retina: 8.0" "Group enriched" "Detected in some" 4 "Retinal amacrine cells: 132.3;Retinal bipolar cells: 187.8" "Cell type enhanced" "Detected in many" "midbrain-derived inhibitory: 132.5;thalamic excitatory: 98.5" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 3.8;Testicular Germ Cell Tumor (TCGA): 3.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 6.8" "Lung - Fibroblasts_2, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004714 Uncertain Approved "Nucleoplasm,Nuclear bodies,Cytosol,Acrosome,Equatorial segment,Perinuclear theca" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "Nucleoplasm, Acrosome, Equatorial segment, Perinuclear theca" "Nuclear bodies, Cytosol" "HPA004714: " "unprognostic (2.08e-1)" "unprognostic (2.02e-1)" "unprognostic (3.20e-2)" "unprognostic (2.05e-1)" "unprognostic (5.70e-2)" "unprognostic (4.51e-2)" CACNA1H Cav3.2 ENSG00000196557 "Calcium voltage-gated channel subunit alpha1 H" O95180 16 1153106-1221771 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 103.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 33.1;Corticotrophs: 41.1;Gonadotrophs: 76.5;Lactotrophs: 59.3;Loop of henle epithelial cells: 35.1;Pericytes: 42.7;Peritubular myoid cells: 32.9;Retinal bipolar cells: 33.4;Smooth muscle cells: 33.0;Somatotrophs: 46.6;Thyrotrophs: 37.2;Vascular smooth muscle cells: 77.6" "Cell type enhanced" "Detected in many" "medium spiny neuron: 36.6;vascular associated smooth muscle cell: 48.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Adrenal gland - Adrenal cortex cells, Lung - Smooth muscle cells, Minor Salivary Gland - Endothelial cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA039125 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 33: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 110: Mural cells - ECM organization" 2 "Nucleoplasm, Vesicles" "HPA039125: " "unprognostic (3.35e-3)" "unprognostic (3.36e-3)" "unprognostic (2.29e-1)" "unprognostic (1.84e-2)" "unprognostic (3.52e-2)" "unprognostic (1.76e-1)" "unprognostic (4.50e-3)" "unprognostic (4.13e-2)" "unprognostic (8.95e-2)" "unprognostic (1.14e-1)" "unprognostic (2.82e-1)" "unprognostic (1.14e-2)" "potential prognostic unfavorable (9.56e-5)" "unprognostic (1.26e-1)" "unprognostic (8.61e-3)" "unprognostic (1.08e-1)" "unprognostic (2.76e-2)" "unprognostic (1.93e-3)" "unprognostic (8.97e-2)" "unprognostic (1.05e-2)" "potential prognostic favorable (2.72e-5)" "unprognostic (3.33e-1)" "unprognostic (1.01e-1)" "unprognostic (2.61e-1)" "unprognostic (3.36e-2)" "unprognostic (1.41e-1)" "unprognostic (1.64e-2)" "unprognostic (3.97e-2)" "unprognostic (1.51e-2)" "unprognostic (3.90e-1)" CACNA1I Cav3.3 ENSG00000100346 "Calcium voltage-gated channel subunit alpha1 I" Q9P0X4 22 39570753-39689735 "FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.7;thyroid gland: 5.1" "Cell type enhanced" "Detected in some" "Adrenal cortex cells: 8.0;Brain excitatory neurons: 26.4;Brain inhibitory neurons: 23.8;Other brain neurons: 11.4;Retinal amacrine cells: 107.2;Retinal bipolar cells: 33.3;Thymic myoid cells: 8.2" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in single" 5 "Thyroid Carcinoma (TCGA): 3.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 2.8;Rhabdoid: 1.3" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066992 Approved "Plasma membrane,Cell Junctions,Acrosome" NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 24: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" 2 "Plasma membrane" "Cell Junctions, Acrosome" "HPA066992: " "unprognostic (1.71e-1)" "unprognostic (1.64e-2)" CACNA1S "CACNL1A3, Cav1.1, HOKPP, hypoPP, MHS5" ENSG00000081248 "Calcium voltage-gated channel subunit alpha1 S" Q13698 1 201039512-201112451 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Calmodulin-binding, Ion channel, Voltage-gated channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 85 "skeletal muscle: 238.7;tongue: 180.4" "Cell type enriched" "Detected in some" 11 "Myonuclei: 437.2" "Cell type enhanced" "Detected in some" "vascular associated smooth muscle cell: 5.7" "Cancer enriched" "Detected in single" 5 "Head and Neck Squamous Cell Carcinoma (TCGA): 1.2" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "breast cancer: 1.1" "Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Testis - Late spermatids" "Region enhanced" "Detected in single" "olfactory bulb: 1.8" "Region enriched" "Detected in single" 5 "olfactory bulb: 3.8" "CAB009507, HPA048892, HPA056815" Enhanced Approved "Acrosome,Equatorial segment" NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 19: Astrocytes - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 4 "Acrosome, Equatorial segment" "CAB009507: , HPA048892: , HPA056815: " "unprognostic (1.22e-2)" CACNA2D1 "alpha2delta-1, CACNA2, CACNL2A, LINC01112, lncRNA-N3, MHS3" ENSG00000153956 "Calcium voltage-gated channel auxiliary subunit alpha2delta 1" P54289 7 81946444-82443956 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 72.5;tongue: 70.5" "Cell type enhanced" "Detected in many" "Adipocytes: 818.1;Adrenal cortex cells: 773.2;Brain excitatory neurons: 795.1;Corticotrophs: 2214.6;Lactotrophs: 786.9;Myonuclei: 3245.4;Pituicytes/FSCs: 726.6;Thyrotrophs: 1301.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 30.6" "Minor Salivary Gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008213, HPA008621" Enhanced "Intracellular and membrane" Transport NA NA 94000000 "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 14: Neurons - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 3 "HPA008213: , HPA008621: " "unprognostic (2.32e-1)" "unprognostic (6.73e-3)" "unprognostic (1.74e-1)" "unprognostic (9.95e-2)" "unprognostic (1.38e-2)" "unprognostic (1.59e-1)" "unprognostic (2.32e-1)" "unprognostic (6.85e-3)" "unprognostic (1.15e-1)" "unprognostic (2.15e-2)" "unprognostic (4.28e-3)" "unprognostic (1.06e-2)" "unprognostic (4.36e-3)" "unprognostic (1.91e-1)" "unprognostic (2.94e-1)" "unprognostic (2.04e-1)" "unprognostic (2.00e-1)" "unprognostic (1.57e-1)" "unprognostic (2.93e-1)" "unprognostic (1.38e-2)" "unprognostic (5.54e-2)" "unprognostic (8.16e-3)" "unprognostic (9.76e-3)" "unprognostic (6.98e-3)" "unprognostic (2.02e-1)" "unprognostic (3.22e-3)" "unprognostic (2.67e-1)" "unprognostic (5.60e-2)" CACNA2D2 "alpha2delta-2, KIAA0558" ENSG00000007402 "Calcium voltage-gated channel auxiliary subunit alpha2delta 2" Q9NY47 3 50362613-50504244 "Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 46.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 82.0;Alveolar cells type 2: 298.6;Brain inhibitory neurons: 51.6;Corticotrophs: 95.8;Oocytes: 110.5;Other brain neurons: 62.7;Pancreatic islet cells: 51.0;Retinal amacrine cells: 169.8;Transitional alveolar cells: 96.3;Tuft cells: 46.1" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 112.6" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 25.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Neuroblastoma: 26.8;thyroid cancer: 13.2" "Breast - Breast glandular cells, Colon - Colon enteroendocrine cells, Kidney - Macrophages, Lung - Alveolar cells type 2, Pancreas - Alpha cells, Pituitary gland - Corticotropes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034771 Enhanced Approved "Plasma membrane,Cytosol,Flagellar centriole,Mid piece" NA NA 1400000 "Cluster 11: T-cells - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 81: Alveolar cells - Lung function" 1 Cytosol "Plasma membrane, Flagellar centriole, Mid piece" "HPA034771: " "unprognostic (3.86e-1)" "unprognostic (1.61e-1)" "unprognostic (1.02e-2)" "unprognostic (2.63e-2)" "unprognostic (1.05e-1)" "unprognostic (3.13e-2)" "unprognostic (2.66e-2)" "potential prognostic favorable (1.21e-4)" "unprognostic (2.36e-3)" "unprognostic (6.71e-3)" "unprognostic (1.45e-1)" "unprognostic (2.14e-1)" "unprognostic (2.16e-1)" "potential prognostic favorable (2.42e-4)" "unprognostic (2.83e-1)" "unprognostic (2.50e-1)" "unprognostic (2.19e-2)" "unprognostic (2.67e-2)" "unprognostic (2.18e-1)" "unprognostic (5.44e-2)" "unprognostic (2.64e-1)" "unprognostic (5.68e-3)" CACNA2D3 "alpha2delta-3, HSA272268" ENSG00000157445 "Calcium voltage-gated channel auxiliary subunit alpha2delta 3" Q8IZS8 3 54122547-55074557 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 16.4;skeletal muscle: 9.3;tongue: 10.0" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 989.2;Brain excitatory neurons: 514.4;Brain inhibitory neurons: 1245.3;Corticotrophs: 724.3;Distal convoluted tubule cells: 1105.1;Epicardial cells: 502.6;Loop of henle epithelial cells: 1054.9;Myonuclei: 1035.9;Oligodendrocyte progenitor cells: 454.0;Pituicytes/FSCs: 808.5;Pituitary stem cells: 657.7;Retinal ganglion cells: 544.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030849 Uncertain "Nucleoplasm,Principal piece" NA NA 46000 "Cluster 78: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" "Nucleoplasm, Principal piece" "HPA030849: " "unprognostic (8.69e-2)" "unprognostic (2.46e-2)" "unprognostic (7.21e-2)" "unprognostic (7.72e-2)" "unprognostic (1.40e-1)" CACNA2D4 alpha2delta-4 ENSG00000151062 "Calcium voltage-gated channel auxiliary subunit alpha2delta 4" Q7Z3S7 12 1791963-1918666 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 39 "retina: 18.7" "Group enriched" "Detected in some" 7 "Early spermatids: 51.5;Late spermatids: 124.1" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 6.1;hippocampal dentate gyrus: 11.8" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 8 "dendritic cells: 2.9;monocytes: 4.4;T-cells: 4.2" "Group enriched" "Detected in some" 4 "Leukemia: 7.5;lymphoma: 3.1;Sarcoma: 2.9" "Adrenal gland - Macrophages, Kidney - Fibroblasts, Minor Salivary Gland - Macrophages" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA031952 Uncertain Approved "Mid piece,Principal piece" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 42: Retina - Visual perception" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" "Mid piece, Principal piece" "HPA031952: " "unprognostic (1.31e-1)" "unprognostic (2.12e-1)" "unprognostic (7.25e-2)" "unprognostic (1.48e-2)" "unprognostic (2.80e-1)" "unprognostic (1.19e-2)" CACNB1 CACNLB1 ENSG00000067191 "Calcium voltage-gated channel auxiliary subunit beta 1" Q02641 17 39173453-39197702 "FDA approved drug targets, Predicted intracellular proteins" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "skeletal muscle: 314.2;tongue: 206.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 23.3;Astrocytes: 30.7;Bergmann glia: 26.4;Myonuclei: 95.8;Thymic myoid cells: 134.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023343 Approved NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 51: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 5 "HPA023343: " "unprognostic (2.93e-2)" "unprognostic (3.05e-2)" "unprognostic (8.83e-2)" "unprognostic (1.23e-1)" "potential prognostic unfavorable (7.01e-4)" "unprognostic (1.54e-1)" "unprognostic (3.93e-2)" "unprognostic (1.60e-2)" "unprognostic (7.60e-3)" "potential prognostic unfavorable (3.79e-6)" "unprognostic (7.36e-3)" "unprognostic (4.72e-2)" "unprognostic (1.11e-2)" "potential prognostic favorable (2.23e-4)" "unprognostic (1.42e-1)" "unprognostic (3.47e-1)" "unprognostic (2.92e-2)" "potential prognostic unfavorable (8.20e-5)" "unprognostic (2.18e-1)" "unprognostic (1.47e-1)" "unprognostic (1.58e-2)" "unprognostic (7.52e-2)" "unprognostic (3.81e-1)" "unprognostic (2.40e-2)" "unprognostic (8.54e-2)" "unprognostic (5.71e-2)" "unprognostic (1.15e-1)" "unprognostic (1.79e-1)" "unprognostic (9.44e-2)" CACNB2 "CACNLB2, MYSB" ENSG00000165995 "Calcium voltage-gated channel auxiliary subunit beta 2" Q08289 10 18140424-18543557 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Brugada syndrome, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 19.5" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 1457.3;Bergmann glia: 1424.3;Cardiomyocytes: 1929.9;Choroid plexus epithelial cells: 1612.2;Cone photoreceptor cells: 1931.4;Corticotrophs: 1282.4;Gonadotrophs: 1643.6;Lactotrophs: 1636.8;Neuroendocrine cells: 1410.7;Pituicytes/FSCs: 1486.1;Pituitary stem cells: 1369.1;Retinal pigment epithelial cells: 2600.4;Rod photoreceptor cells: 2325.5;Somatotrophs: 1707.7;Thyrotrophs: 1607.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Cardiomyocytes, Kidney - Ascending Loop of Henle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035326 Enhanced NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 23: Choroid plexus - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" 3 "HPA035326: " "unprognostic (8.18e-3)" "unprognostic (5.37e-2)" "unprognostic (4.59e-2)" "unprognostic (2.23e-1)" "unprognostic (1.63e-1)" "unprognostic (1.23e-2)" "potential prognostic favorable (9.70e-4)" "unprognostic (4.28e-2)" "unprognostic (3.92e-2)" "potential prognostic favorable (7.28e-4)" "unprognostic (1.03e-2)" "unprognostic (2.91e-1)" "unprognostic (2.06e-3)" "unprognostic (3.05e-1)" "unprognostic (1.96e-2)" "unprognostic (1.32e-1)" "unprognostic (6.61e-3)" "unprognostic (1.10e-1)" "unprognostic (2.90e-1)" "unprognostic (2.14e-2)" "unprognostic (1.43e-1)" "unprognostic (1.81e-2)" "unprognostic (5.19e-2)" CACNB3 CACNLB3 ENSG00000167535 "Calcium voltage-gated channel auxiliary subunit beta 3" P54284 12 48813794-48828941 "Essential proteins, FDA approved drug targets, Predicted intracellular proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 74.6" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 32.3;Ovarian stromal cells: 29.3;Respiratory ionocytes: 38.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.8" "Lineage enriched" "Detected in single" 10 "T-cells: 1.8" "Low cancer specificity" "Detected in all" "Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059515 Approved "Golgi apparatus,Vesicles" NA NA "Cluster 65: Brain - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 94: Gonadal somatic cells - Mixed function" 15 "Golgi apparatus, Vesicles" "HPA059515: " "unprognostic (5.27e-3)" "unprognostic (1.99e-3)" "unprognostic (2.82e-2)" "unprognostic (2.00e-2)" "unprognostic (2.02e-1)" "unprognostic (5.10e-2)" "unprognostic (2.68e-3)" "unprognostic (9.55e-3)" "unprognostic (1.42e-1)" "unprognostic (4.83e-2)" "potential prognostic unfavorable (3.59e-4)" "unprognostic (2.20e-1)" "unprognostic (1.89e-1)" "unprognostic (2.20e-2)" "unprognostic (8.20e-2)" "unprognostic (9.77e-3)" "unprognostic (1.54e-1)" "unprognostic (8.73e-2)" "unprognostic (2.34e-1)" "unprognostic (6.68e-2)" "unprognostic (2.29e-1)" "unprognostic (1.37e-2)" "unprognostic (8.90e-3)" "unprognostic (1.04e-1)" "unprognostic (1.03e-1)" "unprognostic (9.61e-2)" "unprognostic (1.12e-1)" "unprognostic (8.44e-3)" "unprognostic (4.18e-2)" "unprognostic (9.33e-2)" "unprognostic (1.26e-1)" CACNB4 EJM4 ENSG00000182389 "Calcium voltage-gated channel auxiliary subunit beta 4" O00305 2 151832771-152099167 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 24.9;skin 1: 6.9" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 237.1;Choroid plexus epithelial cells: 436.1;Distal convoluted tubule cells: 623.7;Gonadotrophs: 237.6;Medullary thymic epithelial cells: 285.6;Renal connecting tubule cells: 267.3;Retinal amacrine cells: 201.4;Retinal pigment epithelial cells: 294.1;Sertoli cells: 867.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "neutrophil: 3.4" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.4" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Adipose progenitor cells, Lung - Alveolar cells type 2, Testis - Sertoli cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015601 Approved NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 27: Cerebellum - Synaptic function" "Cluster 15: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 3 "HPA015601: " "unprognostic (1.84e-1)" "unprognostic (1.59e-1)" "unprognostic (2.29e-1)" "unprognostic (1.93e-1)" "unprognostic (1.55e-2)" "unprognostic (1.83e-1)" "unprognostic (2.86e-2)" "unprognostic (1.82e-1)" "unprognostic (1.77e-1)" CACNG1 CACNLG ENSG00000108878 "Calcium voltage-gated channel auxiliary subunit gamma 1" Q06432 17 67044554-67056797 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 56 "skeletal muscle: 311.7;tongue: 113.6" "Group enriched" "Detected in some" 26 "Myonuclei: 127.4;Thymic myoid cells: 118.3" "Cell type enhanced" "Detected in some" "Bergmann glia: 1.6;oligodendrocyte precursor cell: 1.9" "Cancer enhanced" "Detected in some" "Breast Invasive Carcinoma (TCGA): 2.4;Head and Neck Squamous Cell Carcinoma (TCGA): 2.7" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Breast glandular cells" "Region enriched" "Detected in single" 6 "basal ganglia: 3.4" "Low region specificity" "Detected in many" NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 33: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 15 "unprognostic (5.34e-2)" "unprognostic (4.59e-1)" "unprognostic (1.47e-1)" "unprognostic (2.25e-3)" "unprognostic (1.18e-2)" CACNG2 "MGC138502, MGC138504, stargazin" ENSG00000166862 "Calcium voltage-gated channel auxiliary subunit gamma 2" Q9Y698 22 36560857-36703752 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 10.3;retina: 2.6" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 89.0;Brain inhibitory neurons: 109.8;Corticotrophs: 174.3;Oligodendrocyte progenitor cells: 70.8;Other brain neurons: 75.1;Retinal amacrine cells: 164.0;Retinal bipolar cells: 36.9;Retinal ganglion cells: 108.2;Retinal horizontal cells: 212.4" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 291.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Neuroblastoma: 1.1" "Adrenal gland - Adrenal medulla cells, Pituitary gland - Corticotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 6 "unprognostic (2.62e-2)" CACNG3 ENSG00000006116 "Calcium voltage-gated channel auxiliary subunit gamma 3" O60359 16 24256335-24362412 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 67.4" "Cell type enriched" "Detected in some" 4 "Retinal horizontal cells: 771.3" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in single" 12 "Glioblastoma Multiforme (TCGA): 1.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 36 "Bone cancer: 3.6" "Adrenal gland - Adrenal medulla cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077238 Enhanced NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" 5 "HPA077238: " "unprognostic (5.35e-2)" "unprognostic (2.06e-1)" CACNG4 "MGC11138, MGC24983" ENSG00000075461 "Calcium voltage-gated channel auxiliary subunit gamma 4" Q9UBN1 17 66964707-67033398 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 58.1" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 42.5;Alveolar cells type 1: 104.3;Bergmann glia: 88.6;Brain inhibitory neurons: 73.5;Breast hormone-responsive cells: 29.4;Oligodendrocyte progenitor cells: 284.4;Other brain neurons: 38.7;Respiratory ciliated cells: 39.4" "Cell type enhanced" "Detected in many" "medium spiny neuron: 165.2;oligodendrocyte precursor cell: 321.2" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 43.6;Glioblastoma Multiforme (TCGA): 56.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 65.6" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Breast - Breast glandular cells, Lung - Alveolar cells type 1, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Alpha cells, Prostate - Prostate glandular cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "basal ganglia: 155.8" "HPA005803, HPA065370" Enhanced Approved Vesicles NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 28 Vesicles "HPA005803: , HPA065370: " "unprognostic (5.77e-2)" "unprognostic (2.26e-1)" "unprognostic (4.77e-2)" "unprognostic (8.08e-2)" "unprognostic (4.22e-2)" "unprognostic (9.82e-2)" "unprognostic (7.57e-2)" "unprognostic (1.54e-2)" "unprognostic (2.54e-2)" "unprognostic (1.59e-1)" "unprognostic (2.71e-1)" "potential prognostic unfavorable (8.75e-4)" "unprognostic (2.02e-2)" "unprognostic (1.30e-1)" "unprognostic (6.93e-3)" "unprognostic (4.88e-2)" "unprognostic (1.02e-1)" "unprognostic (7.95e-3)" "unprognostic (6.77e-2)" "unprognostic (6.20e-3)" "unprognostic (1.25e-1)" "unprognostic (8.90e-2)" "unprognostic (1.91e-1)" "unprognostic (5.36e-3)" "unprognostic (1.31e-1)" "unprognostic (8.30e-2)" "unprognostic (6.46e-2)" CACNG5 ENSG00000075429 "Calcium voltage-gated channel auxiliary subunit gamma 5" Q9UF02 17 66835117-66894751 "FDA approved drug targets, Predicted membrane proteins" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "retina: 14.6" "Group enriched" "Detected in some" 5 "Oligodendrocyte progenitor cells: 53.8;Retinal amacrine cells: 140.2;Retinal ganglion cells: 104.3;Retinal horizontal cells: 170.3" "Cell type enhanced" "Detected in many" "eccentric medium spiny neuron: 58.5;oligodendrocyte precursor cell: 52.4;thalamic excitatory: 32.0" "Cancer enhanced" "Detected in single" "Glioblastoma Multiforme (TCGA): 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 1.0;breast cancer: 1.5;prostate cancer: 1.0" "Colon - Colon enteroendocrine cells, Pancreas - Beta cells" "Region enhanced" "Detected in all" "olfactory bulb: 124.3" "Low region specificity" "Detected in many" HPA050115 Uncertain NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 109: Neurons - Neuronal signaling" "HPA050115: " "unprognostic (6.07e-3)" "unprognostic (3.71e-2)" CACNG6 ENSG00000130433 "Calcium voltage-gated channel auxiliary subunit gamma 6" Q9BXT2 19 53991637-54012666 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "skeletal muscle: 84.9;tongue: 28.0" "Group enriched" "Detected in some" 4 "Myonuclei: 101.5;Respiratory ciliated cells: 46.3;Thymic myoid cells: 28.6" "Cell type enriched" "Detected in some" 11 "ependymal cell: 13.3" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 6.7" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 107 "basophil: 13.4;eosinophil: 8.0" "Lineage enriched" "Detected in single" 134 "granulocytes: 13.4" "Cancer enhanced" "Detected in many" "Myeloma: 11.9;pancreatic cancer: 12.2" "Lung - Respiratory ciliated cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA056615 Approved "Nucleoli fibrillar center,Cytosol" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 46: Brainstem - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" "Nucleoli fibrillar center" Cytosol "HPA056615: " "unprognostic (3.73e-1)" "unprognostic (4.22e-2)" "potential prognostic favorable (7.35e-4)" "unprognostic (1.12e-1)" "unprognostic (6.41e-2)" "unprognostic (7.26e-1)" "unprognostic (1.43e-1)" "unprognostic (3.19e-1)" "unprognostic (5.01e-2)" "unprognostic (1.84e-1)" "unprognostic (2.85e-1)" CACNG7 ENSG00000105605 "Calcium voltage-gated channel auxiliary subunit gamma 7" P62955 19 53909278-53943950 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 78.7" "Cell type enriched" "Detected in some" 6 "Retinal horizontal cells: 440.7" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in some" 16 "Glioblastoma Multiforme (TCGA): 52.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Bile duct cancer: 18.4;Neuroblastoma: 32.0;Rhabdoid: 31.4;thyroid cancer: 10.6" "Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 13 "unprognostic (2.57e-1)" "unprognostic (2.33e-1)" "unprognostic (7.02e-2)" CACNG8 ENSG00000142408 "Calcium voltage-gated channel auxiliary subunit gamma 8" Q8WXS5 19 53962937-53990215 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 41 "brain: 34.0" "Cell type enhanced" "Detected in many" "Bergmann glia: 43.5;Brain excitatory neurons: 76.2;Brain inhibitory neurons: 86.1;Early primary spermatocytes: 21.0;Oligodendrocyte progenitor cells: 43.2;Other brain neurons: 53.9;Retinal amacrine cells: 42.8;Retinal horizontal cells: 80.1" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in single" "Glioblastoma Multiforme (TCGA): 2.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "basophil: 5.4" "Lineage enriched" "Detected in single" 29 "granulocytes: 5.4" "Cancer enhanced" "Detected in many" "Rhabdoid: 12.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041351 Enhanced NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" "HPA041351: " "unprognostic (7.79e-2)" "unprognostic (1.19e-1)" "unprognostic (1.73e-2)" "unprognostic (2.25e-1)" CACTIN "C19orf29, fSAPc, NY-REN-24" ENSG00000105298 "Cactin, spliceosome C complex subunit" Q8WUQ7 19 3610645-3626815 "Essential proteins, Predicted intracellular proteins" "Immunity, Innate immunity, mRNA processing, mRNA splicing" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042504, HPA042548" Approved Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 20: Non-specific - Transcription regulation" 10 "Nucleoplasm, Nuclear speckles" Cytosol "HPA042504: , HPA042548: " "potential prognostic favorable (3.02e-4)" "unprognostic (9.26e-2)" "unprognostic (1.22e-2)" "unprognostic (3.44e-3)" "unprognostic (8.77e-2)" "unprognostic (2.05e-1)" "unprognostic (3.01e-3)" "unprognostic (2.09e-2)" "unprognostic (6.18e-2)" "unprognostic (2.48e-1)" "unprognostic (1.98e-1)" "unprognostic (2.18e-1)" "unprognostic (7.90e-3)" "unprognostic (1.53e-1)" "unprognostic (8.65e-2)" "unprognostic (4.44e-2)" "unprognostic (6.87e-2)" "unprognostic (2.21e-2)" "unprognostic (1.43e-1)" "unprognostic (1.31e-2)" "unprognostic (1.79e-1)" "unprognostic (2.01e-2)" "unprognostic (2.85e-1)" "unprognostic (6.09e-3)" "unprognostic (1.44e-2)" "unprognostic (1.53e-2)" "unprognostic (3.79e-2)" "unprognostic (2.19e-2)" "unprognostic (5.01e-3)" CACUL1 "C10orf46, CAC1, FLJ40409, MGC33215" ENSG00000151893 "CDK2 associated cullin domain 1" Q86Y37 10 118674167-118755249 "Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 525.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050611 Uncertain Nucleoplasm NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 52: Non-specific - Mitochondria" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 7 Nucleoplasm "HPA050611: " "unprognostic (6.08e-2)" "unprognostic (2.86e-2)" "unprognostic (1.11e-1)" "unprognostic (4.04e-1)" "unprognostic (2.16e-1)" "unprognostic (2.07e-1)" "unprognostic (3.38e-3)" "unprognostic (2.53e-1)" "unprognostic (4.71e-2)" "potential prognostic favorable (3.45e-4)" "unprognostic (4.93e-2)" "unprognostic (3.25e-2)" "potential prognostic unfavorable (3.70e-5)" "unprognostic (1.67e-1)" "unprognostic (6.98e-2)" "unprognostic (5.43e-2)" "unprognostic (1.01e-1)" "unprognostic (7.10e-2)" "potential prognostic unfavorable (3.21e-4)" "unprognostic (1.40e-2)" "unprognostic (8.31e-3)" "unprognostic (2.48e-2)" "unprognostic (2.61e-1)" "unprognostic (2.50e-1)" "unprognostic (1.77e-1)" "unprognostic (3.14e-1)" "unprognostic (4.88e-2)" "unprognostic (3.76e-2)" "unprognostic (8.37e-3)" CACYBP "S100A6BP, SIP" ENSG00000116161 "Calcyclin binding protein" Q9HB71 1 174999163-175012027 "Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Megakaryocytes: 321.4;Migrating cytotrophoblasts: 352.1;Oocytes: 548.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025753, HPA057038" Enhanced Enhanced Nucleoplasm,Cytosol NA NA 140000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 34: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 75: Non-specific - Chaperones and protein folding" 46 Cytosol Nucleoplasm "HPA025753: , HPA057038: " "unprognostic (1.16e-1)" "unprognostic (1.24e-3)" "unprognostic (1.67e-1)" "unprognostic (3.47e-1)" "unprognostic (2.95e-1)" "unprognostic (9.46e-3)" "unprognostic (2.05e-1)" "unprognostic (2.70e-2)" "unprognostic (1.06e-2)" "potential prognostic unfavorable (3.49e-4)" "potential prognostic favorable (8.22e-4)" "unprognostic (1.45e-1)" "potential prognostic unfavorable (1.17e-5)" "potential prognostic unfavorable (7.85e-6)" "unprognostic (6.09e-3)" "potential prognostic unfavorable (4.62e-4)" "unprognostic (2.23e-2)" "unprognostic (5.64e-2)" "unprognostic (1.08e-1)" "unprognostic (5.45e-2)" "unprognostic (1.02e-1)" "unprognostic (4.13e-1)" "unprognostic (3.98e-3)" "unprognostic (3.76e-2)" "unprognostic (2.13e-1)" "unprognostic (1.85e-1)" "unprognostic (4.95e-3)" "unprognostic (2.10e-1)" "unprognostic (3.87e-2)" "unprognostic (1.94e-1)" "unprognostic (1.55e-1)" CAD GATD4 ENSG00000084774 "Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase" P27708 2 27217369-27243943 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Pyrimidine biosynthesis" "Allosteric enzyme, Hydrolase, Ligase, Multifunctional enzyme, Transferase" "Cancer-related genes, Congenital disorder of glycosylation, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007781, HPA065158, HPA069341" Supported Supported Cytosol NA No 300000 "Cluster 33: Non-specific - ATP binding" "Cluster 64: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 17: Non-specific - RNA processing" 54 Cytosol "CAB007781: , HPA065158: , HPA069341: " "unprognostic (1.53e-1)" "unprognostic (2.23e-1)" "unprognostic (8.47e-3)" "unprognostic (3.03e-2)" "unprognostic (1.85e-2)" "unprognostic (2.53e-1)" "unprognostic (1.09e-1)" "unprognostic (3.80e-1)" "unprognostic (8.73e-2)" "unprognostic (3.91e-3)" "validated prognostic unfavorable (5.72e-9)" "validated prognostic unfavorable (3.48e-4)" "unprognostic (8.78e-2)" "validated prognostic unfavorable (1.51e-11)" "validated prognostic unfavorable (1.21e-4)" "unprognostic (6.04e-3)" "unprognostic (5.20e-3)" "unprognostic (3.38e-3)" "unprognostic (8.84e-2)" "unprognostic (7.33e-2)" "unprognostic (2.15e-3)" "unprognostic (2.64e-1)" "unprognostic (1.29e-1)" "unprognostic (1.21e-2)" "unprognostic (4.31e-1)" "unprognostic (2.14e-2)" "unprognostic (4.46e-1)" "unprognostic (2.53e-2)" "unprognostic (9.72e-2)" "unprognostic (1.32e-2)" "unprognostic (6.92e-2)" CADM1 "BL2, IGSF4, IGSF4A, Necl-2, NECL2, RA175, ST17, SYNCAM, SYNCAM1, TSLC1" ENSG00000182985 "Cell adhesion molecule 1" Q9BY67 11 115169218-115504957 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell adhesion, Differentiation, Host-virus interaction, Immunity, Spermatogenesis" "Developmental protein" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 266.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 1114.7;Astrocytes: 1468.7;Cone photoreceptor cells: 1409.7;Müller glia: 1212.3;Retinal bipolar cells: 2456.0;Rod photoreceptor cells: 4758.6;Sertoli cells: 2066.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 8.0;myeloid DC: 8.1" "Group enriched" "Detected in many" 5 "dendritic cells: 8.1;T-cells: 8.0" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Colon - Enteric glia cells, Lung - Alveolar cells type 1, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB037266 Enhanced Supported "Plasma membrane" NA NA 35000000 "Cluster 33: Non-specific - ATP binding" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 69: Skin cancer - ECM organization" "Cluster 79: Photoreceptor cells - Phototransduction" 5 "Plasma membrane" "CAB037266: " "unprognostic (6.41e-2)" "unprognostic (1.23e-1)" "unprognostic (1.21e-2)" "unprognostic (3.84e-1)" "unprognostic (1.35e-2)" "unprognostic (4.70e-1)" "unprognostic (4.29e-2)" "potential prognostic unfavorable (1.18e-4)" "unprognostic (1.39e-1)" "unprognostic (3.38e-1)" "unprognostic (8.91e-3)" "unprognostic (4.27e-2)" "unprognostic (1.13e-1)" "unprognostic (1.74e-2)" "potential prognostic favorable (8.77e-5)" "unprognostic (1.14e-3)" "unprognostic (6.86e-3)" "unprognostic (1.50e-1)" "unprognostic (5.52e-2)" "unprognostic (7.08e-2)" "unprognostic (3.89e-3)" "unprognostic (1.02e-2)" "unprognostic (1.30e-1)" "unprognostic (1.54e-1)" "unprognostic (1.68e-2)" "unprognostic (2.43e-2)" "unprognostic (9.40e-2)" "unprognostic (2.86e-2)" "unprognostic (3.04e-1)" "unprognostic (9.94e-2)" "unprognostic (3.11e-2)" CADM2 "IGSF4D, Necl-3, NECL3, SynCAM2" ENSG00000175161 "Cell adhesion molecule 2" Q8N3J6 3 84958989-86074429 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 15 "brain: 48.5;retina: 87.9" "Cell type enhanced" "Detected in many" "Astrocytes: 3145.8;Bergmann glia: 3799.8;Brain excitatory neurons: 4499.0;Brain inhibitory neurons: 2991.8;Cone photoreceptor cells: 5550.0;Corticotrophs: 4599.3;Lactotrophs: 2383.8;Myosatellite cells: 3326.0;Oligodendrocyte progenitor cells: 4761.1;Oligodendrocytes: 6102.9;Other brain neurons: 2714.0;Retinal amacrine cells: 1985.4;Retinal bipolar cells: 2361.6;Retinal ganglion cells: 1846.4;Rod photoreceptor cells: 8749.3;Schwann cells: 2169.8" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in some" 8 "Glioblastoma Multiforme (TCGA): 19.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "basophil: 6.0" "Lineage enriched" "Detected in many" 6 "granulocytes: 6.0" "Cancer enhanced" "Detected in some" "Rhabdoid: 11.1;Sarcoma: 8.5" "Adrenal gland - Adrenal medulla cells, Breast - Endothelial cells, Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010024 Enhanced NA NA 74000 "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 11: Neuronal - Sensory perception" "Cluster 35: Neurons - Synaptic function & neurogenesis" "HPA010024: " "unprognostic (9.11e-2)" "unprognostic (5.91e-3)" "unprognostic (3.55e-2)" "unprognostic (1.26e-2)" "unprognostic (2.23e-1)" CADM3 "BIgR, FLJ10698, IGSF4B, Necl-1, NECL1, SynCAM3, TSLL1" ENSG00000162706 "Cell adhesion molecule 3" Q8N126 1 159171609-159203313 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 323.0" "Cell type enhanced" "Detected in some" "Bergmann glia: 58.1;Brain excitatory neurons: 109.7;Brain inhibitory neurons: 83.4;Corticotrophs: 46.6;Ependymal cells: 61.4;Fibroblasts: 45.1;Gonadotrophs: 35.7;Lactotrophs: 45.7;Müller glia: 38.3;Oligodendrocyte progenitor cells: 46.0;Other brain neurons: 70.7;Retinal amacrine cells: 67.2;Retinal bipolar cells: 166.7;Retinal ganglion cells: 42.5;Schwann cells: 132.1;Somatotrophs: 37.7;Thyrotrophs: 43.7" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 62.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 55.7;skin cancer: 20.6" "Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Lung - Fibroblasts_2, Skin - Fibroblasts_2, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002981, CAB025746" Enhanced Supported "Intracellular and membrane" "Cell adhesion" NA NA 4000000 "Cluster 27: Cerebellum - Synaptic function" "Cluster 1: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 1 "CAB025746: , HPA002981: " "unprognostic (8.21e-2)" "unprognostic (1.43e-2)" "unprognostic (1.11e-2)" "unprognostic (2.05e-2)" "unprognostic (1.93e-1)" "unprognostic (6.01e-3)" "unprognostic (1.57e-2)" "unprognostic (3.85e-3)" "unprognostic (1.92e-1)" "unprognostic (6.70e-2)" "unprognostic (3.75e-3)" "unprognostic (3.08e-2)" "unprognostic (1.71e-2)" "unprognostic (4.03e-2)" "unprognostic (4.24e-2)" "unprognostic (4.53e-2)" "unprognostic (2.27e-2)" "unprognostic (3.63e-1)" "unprognostic (3.46e-2)" "unprognostic (1.86e-1)" "unprognostic (1.45e-1)" "unprognostic (5.74e-2)" "unprognostic (6.39e-2)" "unprognostic (3.01e-1)" "unprognostic (1.07e-2)" CADM4 "IGSF4C, Necl-4, SynCAM4, TSLL2" ENSG00000105767 "Cell adhesion molecule 4" Q8NFZ8 19 43622368-43639850 "Predicted membrane proteins" "Cell adhesion" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 203.4" "Cell type enhanced" "Detected in many" "Bergmann glia: 51.6;Late spermatids: 61.4;Oligodendrocyte progenitor cells: 85.9;Oligodendrocytes: 95.2;Schwann cells: 99.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 182.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "plasmacytoid DC: 1.5" "Lineage enriched" "Detected in single" 7 "dendritic cells: 1.5" "Cancer enhanced" "Detected in all" "skin cancer: 123.8" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal cortex cells, Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012612, HPA070705" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 390000 "Cluster 29: Non-specific - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 61: Schwann cells & Melanocytes - Mixed function" 10 "Plasma membrane" "Nucleoplasm, Cytosol" "HPA012612: , HPA070705: " "unprognostic (2.61e-3)" "unprognostic (1.07e-1)" "unprognostic (1.90e-1)" "unprognostic (2.09e-1)" "unprognostic (3.24e-1)" "unprognostic (1.13e-1)" "unprognostic (1.15e-1)" "unprognostic (9.19e-2)" "unprognostic (1.36e-2)" "unprognostic (5.15e-2)" "unprognostic (8.00e-3)" "unprognostic (6.30e-2)" "potential prognostic favorable (6.39e-4)" "unprognostic (6.56e-2)" "unprognostic (1.28e-1)" "unprognostic (9.12e-2)" "unprognostic (2.31e-1)" "unprognostic (5.19e-2)" "potential prognostic favorable (5.67e-4)" "unprognostic (1.46e-1)" "unprognostic (1.72e-1)" "unprognostic (8.09e-3)" "unprognostic (1.84e-1)" "unprognostic (2.82e-1)" "unprognostic (1.08e-1)" "unprognostic (8.36e-2)" "unprognostic (6.58e-2)" "unprognostic (2.72e-1)" "unprognostic (1.22e-2)" "unprognostic (5.91e-2)" "unprognostic (2.61e-1)" CADPS "CAPS, CAPS1, KIAA1121, UNC-31" ENSG00000163618 "Calcium dependent secretion activator" Q9ULU8 3 62398346-62875416 "Plasma proteins, Predicted intracellular proteins" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 77.2;retina: 170.8" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 1297.7;Brain excitatory neurons: 943.5;Brain inhibitory neurons: 1082.0;Cone photoreceptor cells: 1569.1;Gonadotrophs: 865.8;Lactotrophs: 1257.9;Other brain neurons: 1076.5;Pancreatic islet cells: 750.2;Retinal amacrine cells: 1489.5;Retinal bipolar cells: 3076.1;Somatotrophs: 3528.8;Thyrotrophs: 1525.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 21.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 11.1" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Lung - Mast cells, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Somatotropes, Prostate - Fibroblasts, Skin - Fibroblasts_2" HPA059328 Enhanced Supported Approved Vesicles NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 1: Neuronal - Visual perception" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 1 Vesicles "HPA059328: " "unprognostic (7.17e-2)" "unprognostic (1.99e-1)" "unprognostic (2.01e-3)" "unprognostic (8.41e-2)" "potential prognostic favorable (8.00e-4)" "unprognostic (1.81e-1)" "unprognostic (1.69e-2)" "unprognostic (1.11e-2)" "unprognostic (5.25e-2)" "unprognostic (1.64e-3)" "unprognostic (7.38e-2)" "unprognostic (1.88e-1)" "unprognostic (2.87e-1)" "unprognostic (1.42e-1)" "unprognostic (1.40e-1)" "unprognostic (1.91e-2)" "unprognostic (1.38e-1)" CADPS2 CAPS2 ENSG00000081803 "Calcium dependent secretion activator 2" Q86UW7 7 122318411-122886759 "Predicted intracellular proteins" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 160.8" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 1289.5;Lactotrophs: 723.5;Renal collecting duct principal cells: 946.8;Renal connecting tubule cells: 2383.0;Salivary acinar cells: 1009.2;Somatotrophs: 774.7" "Cell type enriched" "Detected in all" 4 "upper rhombic lip: 4043.5" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 206.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 215.4" HPA056398 Approved Nucleoplasm,Vesicles NA NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 2: Neurons - Nucleosome" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 1 "Nucleoplasm, Vesicles" "HPA056398: " "unprognostic (3.90e-3)" "unprognostic (1.62e-1)" "unprognostic (1.47e-1)" "unprognostic (3.12e-1)" "unprognostic (6.98e-2)" "unprognostic (1.11e-1)" "unprognostic (2.79e-2)" "unprognostic (1.69e-2)" "unprognostic (6.95e-2)" "unprognostic (2.29e-1)" "potential prognostic favorable (1.05e-6)" "unprognostic (6.44e-3)" "unprognostic (3.16e-2)" "unprognostic (2.38e-2)" "unprognostic (7.82e-2)" "unprognostic (6.37e-2)" "unprognostic (1.13e-1)" "unprognostic (1.48e-1)" "unprognostic (1.55e-1)" "unprognostic (1.67e-2)" "unprognostic (9.76e-2)" "unprognostic (9.83e-2)" "potential prognostic favorable (9.12e-6)" "unprognostic (5.17e-2)" "unprognostic (7.89e-2)" "unprognostic (1.63e-2)" "unprognostic (1.95e-1)" "unprognostic (1.50e-1)" "unprognostic (2.03e-1)" "unprognostic (3.43e-2)" "unprognostic (3.55e-1)" CAGE1 "bA69L16.7, CT95, CTAG3" ENSG00000164304 "Cancer antigen 1" Q8TC20 6 7326656-7389742 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 23 "testis: 4.7" "Cell type enhanced" "Detected in many" "Early spermatids: 141.7;Epicardial cells: 29.6;Late primary spermatocytes: 125.8;Late spermatids: 82.9;pDCs: 27.7" "Cell type enhanced" "Detected in many" "hippocampal CA4: 4.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA029832 Uncertain NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" 6 "HPA029832: " CALB1 CALB ENSG00000104327 "Calbindin 1" P05937 8 90058608-90095475 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 90.7;kidney: 300.4" "Cell type enhanced" "Detected in some" "Brain inhibitory neurons: 63.7;Cone photoreceptor cells: 80.7;Distal convoluted tubule cells: 244.1;Other brain neurons: 48.7;Renal connecting tubule cells: 442.0;Retinal horizontal cells: 88.1" "Group enriched" "Detected in many" 4 "Bergmann glia: 30.7;hippocampal dentate gyrus: 97.7;LAMP5-LHX6 and Chandelier: 95.1;medium spiny neuron: 115.5;MGE interneuron: 35.5;splatter: 53.3;thalamic excitatory: 58.7" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 156.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 7.0" "Group enriched" "Detected in many" 5 "granulocytes: 5.6;monocytes: 7.0" "Low cancer specificity" "Detected in all" "Colon - Colon enteroendocrine cells" "Region enhanced" "Detected in all" "cerebellum: 430.7" "Group enriched" "Detected in all" 4 "basal ganglia: 65.5;cerebellum: 159.4" "CAB002138, HPA023099, HPA056734" Enhanced Approved Vesicles NA NA 410000 "Cluster 7: Non-specific - Innate immune response" "Cluster 72: Kidney - Transmembrane transport" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" 5 Vesicles "CAB002138: , HPA023099: , HPA056734: " "unprognostic (5.24e-2)" "unprognostic (3.23e-1)" "unprognostic (1.40e-2)" "unprognostic (5.00e-3)" "unprognostic (7.24e-3)" "unprognostic (1.72e-1)" "unprognostic (4.49e-1)" "unprognostic (4.36e-2)" "unprognostic (6.20e-3)" "unprognostic (4.83e-2)" "unprognostic (1.33e-1)" "unprognostic (1.56e-1)" "unprognostic (1.81e-1)" "unprognostic (9.58e-2)" "unprognostic (1.26e-1)" "unprognostic (8.25e-2)" "unprognostic (1.73e-3)" "unprognostic (1.30e-2)" "unprognostic (4.66e-2)" "unprognostic (1.17e-1)" "unprognostic (1.96e-3)" "unprognostic (1.22e-1)" "unprognostic (1.11e-1)" "unprognostic (2.91e-2)" "unprognostic (7.43e-3)" "unprognostic (2.18e-1)" "unprognostic (7.14e-2)" "unprognostic (9.77e-2)" "unprognostic (6.16e-2)" "unprognostic (3.31e-3)" CALB2 CAL2 ENSG00000172137 "Calbindin 2" P22676 16 71358713-71390436 "Plasma proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 96.3;brain: 304.9" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 45.0;Brain inhibitory neurons: 42.8;Breast lactating cells: 24.2;Esophageal apical cells: 12.1;Mast cells: 51.3;Mesothelial cells: 54.5;Other brain neurons: 113.7;Pituicytes/FSCs: 19.9" "Cell type enhanced" "Detected in all" "CGE interneuron: 159.7;lower rhombic lip: 196.7;thalamic excitatory: 240.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 31.5;pancreatic cancer: 36.3" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Mesothelial cells, Breast - Adipocytes (Breast), Colon - Colon enteroendocrine cells, Lung - Mast cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Prostate - Fibroblasts, Stomach - Fibroblasts, Testis - Leydig cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "thalamus: 647.9" "CAB000106, HPA007305, HPA007306" Enhanced Supported Supported Cytosol NA NA 10000 "Cluster 27: Cerebellum - Synaptic function" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 98: Neurons - Neurotransmission & signaling" 2 Cytosol "CAB000106: , HPA007305: , HPA007306: " "unprognostic (1.75e-1)" "unprognostic (1.19e-1)" "unprognostic (6.35e-2)" "unprognostic (1.24e-1)" "unprognostic (1.79e-3)" "unprognostic (1.62e-1)" "unprognostic (2.84e-2)" "potential prognostic favorable (1.04e-4)" "unprognostic (9.52e-2)" "unprognostic (2.28e-3)" "unprognostic (1.51e-2)" "unprognostic (2.20e-1)" "unprognostic (1.61e-1)" "unprognostic (6.15e-2)" "unprognostic (9.20e-2)" "unprognostic (5.89e-3)" "unprognostic (1.08e-3)" "unprognostic (3.51e-2)" "unprognostic (7.23e-2)" "unprognostic (1.63e-3)" "unprognostic (3.67e-1)" "unprognostic (4.38e-3)" "unprognostic (1.70e-2)" "unprognostic (2.10e-3)" CALCA "CALC1, CGRP, CGRP-alpha" ENSG00000110680 "Calcitonin related polypeptide alpha" "P01258, P06881" 11 14966622-14972354 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins, Transporters" Hormone "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "parathyroid gland: 167.3;thyroid gland: 146.0" "Group enriched" "Detected in some" 5 "Pancreatic islet cells: 46.3;Renal collecting duct intercalated cells: 48.5;Vascular smooth muscle cells: 17.2" "Cell type enriched" "Detected in single" 13 "thalamic excitatory: 5.3" "Cancer enriched" "Detected in many" 4 "Lung Adenocarcinoma (TCGA): 436.5" "Region enhanced" "Detected in many" "pons: 79.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 13 "thyroid cancer: 2800.5" "Colon - Colon enteroendocrine cells, Thyroid gland - Parafollicular cells" "Region enriched" "Detected in all" 5 "pons and medulla: 58.0" "HPA059886, HPA064453" Enhanced Supported "Secreted to blood" Hormone NA NA 49600 470000 "Cluster 69: Parathyroid gland - Mixed function" "Cluster 43: Hindbrain - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 103: Non-specific - Basic cellular processes" 7 "HPA059886: , HPA064453: " "unprognostic (8.93e-2)" "unprognostic (1.74e-1)" "unprognostic (1.97e-1)" "unprognostic (1.03e-1)" "unprognostic (1.24e-1)" "unprognostic (2.90e-2)" "unprognostic (1.14e-2)" "unprognostic (4.91e-3)" "unprognostic (3.87e-1)" "unprognostic (6.91e-2)" "unprognostic (1.10e-1)" "unprognostic (1.91e-1)" "unprognostic (1.79e-1)" "unprognostic (9.27e-2)" "unprognostic (2.60e-1)" "unprognostic (6.63e-2)" "unprognostic (2.99e-3)" "unprognostic (1.55e-3)" CALCB "CALC2, CGRP-II, FLJ30166" ENSG00000175868 "Calcitonin related polypeptide beta" P10092 11 14904997-15082342 "FDA approved drug targets, Plasma proteins, Predicted secreted proteins" Hormone "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 8.7;thyroid gland: 19.3" "Cell type enhanced" "Detected in many" "Adipocytes: 23.2;Early primary spermatocytes: 24.2;Epicardial cells: 61.4;Lacrimal acinar cells: 25.4;Pancreatic acinar cells: 59.1;Pancreatic islet cells: 26.5;Proximal tubule cells: 54.3;Renal collecting duct intercalated cells: 68.3;Salivary acinar cells: 31.7;Sertoli cells: 23.0" "Cell type enhanced" "Detected in many" "thalamic excitatory: 31.5;upper rhombic lip: 50.4" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 13.3;Uterine Corpus Endometrial Carcinoma (TCGA): 31.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Bone cancer: 19.8;colorectal cancer: 60.6;thyroid cancer: 62.5" "Colon - Colon enteroendocrine cells, Skin - Inner root sheath cells, Thyroid gland - Parafollicular cells" "Region enriched" "Detected in some" 7 "pons and medulla: 9.6" "Group enriched" "Detected in all" 5 "amygdala: 42.9;basal ganglia: 101.5;hypothalamus: 69.1;midbrain: 47.2;pons: 56.7" HPA059886 Supported "Secreted to blood" Hormone NA NA 4500 "Cluster 33: Thyroid gland - Tissue development" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 9: T-cells - Adaptive immunity: Regulation" 5 "HPA059886: " "unprognostic (3.87e-2)" "unprognostic (5.16e-2)" "unprognostic (2.40e-1)" "unprognostic (3.60e-1)" "unprognostic (2.34e-1)" "unprognostic (1.12e-1)" "unprognostic (1.55e-1)" "unprognostic (1.69e-1)" "unprognostic (2.57e-2)" "unprognostic (1.87e-1)" "unprognostic (2.12e-1)" "unprognostic (4.38e-2)" CALCOCO1 "calphoglin, Cocoa, KIAA1536" ENSG00000012822 "Calcium binding and coiled-coil domain 1" Q9P1Z2 12 53708517-53727745 "Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038313, HPA038314" Approved Supported Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 24: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 7: Non-specific - Transcription" 33 Cytosol "HPA038313: , HPA038314: " "unprognostic (4.27e-3)" "unprognostic (2.35e-2)" "unprognostic (2.36e-1)" "unprognostic (6.18e-2)" "unprognostic (1.95e-3)" "unprognostic (1.62e-1)" "unprognostic (2.77e-1)" "unprognostic (5.18e-2)" "unprognostic (2.45e-1)" "unprognostic (3.98e-2)" "validated prognostic favorable (3.93e-6)" "validated prognostic favorable (8.43e-5)" "unprognostic (3.20e-3)" "unprognostic (1.71e-2)" "unprognostic (1.68e-1)" "unprognostic (3.28e-2)" "unprognostic (3.75e-2)" "unprognostic (7.86e-2)" "unprognostic (2.22e-1)" "unprognostic (9.33e-2)" "unprognostic (1.67e-3)" "unprognostic (1.50e-1)" "unprognostic (5.23e-2)" "unprognostic (3.77e-1)" "unprognostic (1.34e-1)" "unprognostic (7.51e-3)" "unprognostic (1.55e-2)" "unprognostic (1.46e-1)" "unprognostic (1.16e-1)" "unprognostic (1.18e-1)" "unprognostic (9.03e-2)" CALCOCO2 "MGC17318, NDP52" ENSG00000136436 "Calcium binding and coiled-coil domain 2" Q13137 17 48831018-48866522 "Predicted intracellular proteins" "Autophagy, Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 1460.7;Late primary spermatocytes: 546.1;Late spermatids: 410.2;Retinal pigment epithelial cells: 413.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA022989, HPA023019, HPA023195" Enhanced Supported Vesicles,Cytosol NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 8: Immune cells - Immune response" "Cluster 27: Breast cancer - Unknown function" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 203 Cytosol Vesicles "HPA022989: , HPA023019: , HPA023195: " "unprognostic (6.24e-3)" "unprognostic (1.46e-1)" "unprognostic (4.06e-1)" "unprognostic (1.21e-3)" "unprognostic (3.26e-2)" "unprognostic (5.09e-2)" "unprognostic (1.17e-1)" "unprognostic (1.03e-2)" "unprognostic (1.26e-1)" "unprognostic (1.74e-2)" "potential prognostic favorable (1.23e-7)" "unprognostic (1.40e-3)" "unprognostic (2.52e-1)" "unprognostic (1.30e-1)" "unprognostic (2.73e-1)" "unprognostic (7.12e-2)" "unprognostic (7.31e-2)" "unprognostic (1.56e-2)" "unprognostic (1.70e-1)" "unprognostic (5.22e-2)" "unprognostic (3.82e-2)" "unprognostic (1.30e-1)" "unprognostic (5.79e-2)" "unprognostic (5.28e-2)" "unprognostic (2.11e-2)" "unprognostic (3.59e-1)" "unprognostic (3.55e-1)" "unprognostic (3.23e-1)" "unprognostic (2.33e-1)" "unprognostic (1.10e-1)" "unprognostic (1.46e-2)" CALCR "CT-R, CTR" ENSG00000004948 "Calcitonin receptor" 7 93424486-93574730 "Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.0;kidney: 1.4" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 395.7;Loop of henle epithelial cells: 131.4;Myosatellite cells: 661.1;Renal collecting duct intercalated cells: 184.4" "Group enriched" "Detected in some" 4 "central nervous system macrophage: 45.3;medium spiny neuron: 22.3;splatter: 23.1" "Group enriched" "Detected in some" 5 "Kidney Chromophobe (TCGA): 1.3;Kidney Renal Clear Cell Carcinoma (TCGA): 2.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "testis cancer: 2.6;Uterine cancer: 2.9" "Testis - Early spermatids, Testis - Late spermatids" "Group enriched" "Detected in many" 5 "basal ganglia: 6.3;hypothalamus: 24.6" "Low region specificity" "Detected in all" "HPA028962, HPA061428" Enhanced Supported Approved "Vesicles,Cell Junctions,Centriolar satellite" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 2 "Cell Junctions" "Vesicles, Centriolar satellite" "HPA028962: , HPA061428: " "unprognostic (1.26e-1)" "unprognostic (2.98e-1)" "unprognostic (3.98e-2)" "unprognostic (4.48e-2)" CALCRL "CGRPR, CRLR" ENSG00000064989 "Calcitonin receptor like receptor" Q16602 2 187341964-187448460 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 66.3;lung: 72.4" "Cell type enhanced" "Detected in many" "Adipocytes: 379.9;Bergmann glia: 332.9;Endometrial stromal cells: 222.1;Fibro-adipogenic progenitors: 158.1;Lymphatic endothelial cells: 598.3;Oligodendrocyte progenitor cells: 378.2;Pituicytes/FSCs: 176.1;Vascular endothelial cells: 948.8" "Cell type enhanced" "Detected in many" "Bergmann glia: 365.9;endothelial cell: 403.4;oligodendrocyte precursor cell: 468.1" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 41.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "classical monocyte: 2.6;myeloid DC: 9.2;plasmacytoid DC: 2.6" "Group enriched" "Detected in many" 6 "dendritic cells: 9.2;monocytes: 2.6" "Cancer enhanced" "Detected in many" "Rhabdoid: 12.7;Sarcoma: 23.1" "Adrenal gland - Endothelial cells, Colon - Endothelial cells, Lung - Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008070, HPA046515" Uncertain Supported "Plasma membrane" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 13: Lung - Secretion" "Cluster 43: Hindbrain - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 5 "Plasma membrane" "HPA008070: , HPA046515: " "unprognostic (2.35e-1)" "unprognostic (4.28e-2)" "unprognostic (1.31e-1)" "unprognostic (3.87e-2)" "unprognostic (4.64e-2)" "unprognostic (1.07e-1)" "unprognostic (7.80e-3)" "potential prognostic favorable (6.86e-6)" "unprognostic (4.96e-2)" "unprognostic (2.21e-1)" "validated prognostic favorable (1.58e-10)" "validated prognostic favorable (8.04e-4)" "unprognostic (2.84e-3)" "unprognostic (2.66e-2)" "unprognostic (4.10e-3)" "unprognostic (1.44e-2)" "unprognostic (3.73e-1)" "unprognostic (1.86e-1)" "unprognostic (1.17e-1)" "unprognostic (1.41e-1)" "unprognostic (1.37e-3)" "unprognostic (5.78e-2)" "unprognostic (5.19e-2)" "unprognostic (2.41e-1)" "unprognostic (1.18e-1)" "unprognostic (4.34e-2)" "potential prognostic unfavorable (1.64e-4)" "unprognostic (1.54e-2)" "unprognostic (1.13e-1)" "unprognostic (6.09e-2)" "unprognostic (1.83e-1)" CALD1 "CDM, H-CAD, h-CD, L-CAD" ENSG00000122786 "Caldesmon 1" Q05682 7 134744252-134970729 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Muscle protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 2360.2;Decidual stromal cells: 2069.1;Extravillous trophoblasts: 1516.8;Hepatic stellate cells: 4298.9;Leydig cells: 2586.7;Ovarian stromal cells: 1689.0;Pericytes: 2893.8;Peritubular myoid cells: 2468.1;Salivary myoepithelial cells: 1486.3;Smooth muscle cells: 4434.5;Vascular smooth muscle cells: 3489.9" "Group enriched" "Detected in all" 5 "pericyte: 1943.5;vascular associated smooth muscle cell: 2377.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "neutrophil: 1.9" "Lineage enriched" "Detected in single" 8 "granulocytes: 1.9" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Fibroblasts, Kidney - Fibroblasts, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000006, HPA008066, HPA017330" Enhanced Enhanced "Plasma membrane,Actin filaments" Yes No 46000000 "Cluster 4: Neutrophils - Degranulation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 108 "Plasma membrane, Actin filaments" "CAB000006: , HPA008066: , HPA017330: " "unprognostic (3.34e-2)" "unprognostic (1.63e-1)" "unprognostic (1.72e-1)" "unprognostic (1.82e-2)" "unprognostic (2.38e-3)" "unprognostic (8.10e-2)" "unprognostic (1.33e-1)" "potential prognostic unfavorable (3.64e-4)" "unprognostic (1.29e-1)" "potential prognostic unfavorable (2.70e-4)" "potential prognostic favorable (1.21e-6)" "unprognostic (3.57e-2)" "unprognostic (4.66e-2)" "unprognostic (1.29e-1)" "unprognostic (1.33e-1)" "unprognostic (4.32e-2)" "unprognostic (5.50e-2)" "unprognostic (1.58e-2)" "unprognostic (4.28e-2)" "unprognostic (2.44e-2)" "potential prognostic unfavorable (1.30e-5)" "unprognostic (7.91e-2)" "unprognostic (2.62e-1)" "unprognostic (5.27e-2)" "unprognostic (3.23e-2)" "unprognostic (1.16e-2)" "unprognostic (2.50e-2)" "unprognostic (1.48e-3)" "unprognostic (1.33e-1)" "unprognostic (8.81e-2)" "unprognostic (5.10e-2)" CALHM1 FAM26C ENSG00000185933 "Calcium homeostasis modulator 1" Q8IU99 10 103453240-103458900 "Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Sensory transduction, Taste, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.9" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 1.6;Other brain neurons: 1.4" "Cell type enhanced" "Detected in some" "mammillary body: 4.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 3.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA061816 Enhanced NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 24: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 109: Neurons - Neuronal signaling" 1 "HPA061816: " "unprognostic (2.30e-2)" CALHM2 FAM26B ENSG00000138172 "Calcium homeostasis modulator family member 2" Q9HA72 10 103446786-103452402 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 106.1;Extravillous trophoblasts: 105.2;Fibroblasts: 37.8;Hofbauer cells: 66.9;Leydig cells: 24.7;Lymphatic endothelial cells: 29.5;Ovarian stromal cells: 36.8;Pericytes: 27.5;Vascular endothelial cells: 29.0;Vascular smooth muscle cells: 41.6" "Cell type enhanced" "Detected in many" "endothelial cell: 15.0;leukocyte: 15.2;vascular associated smooth muscle cell: 21.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Lung - Fibroblasts_2, Prostate - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014706 Approved Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 75: Ovary - Mixed function" "Cluster 12: Non-specific - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 3 "Nucleoplasm, Mitochondria" Cytosol "HPA014706: " "unprognostic (7.07e-2)" "unprognostic (5.18e-2)" "unprognostic (3.23e-2)" "unprognostic (1.26e-1)" "unprognostic (8.97e-2)" "unprognostic (1.95e-2)" "unprognostic (8.70e-3)" "unprognostic (2.47e-2)" "unprognostic (2.29e-1)" "unprognostic (1.12e-1)" "unprognostic (3.17e-3)" "unprognostic (2.39e-2)" "unprognostic (2.25e-3)" "unprognostic (1.70e-1)" "unprognostic (5.61e-2)" "unprognostic (5.69e-2)" "unprognostic (1.21e-1)" "unprognostic (4.57e-2)" "unprognostic (3.23e-1)" "unprognostic (8.39e-3)" "unprognostic (5.08e-1)" "unprognostic (8.49e-2)" "unprognostic (9.75e-2)" "unprognostic (2.30e-1)" "unprognostic (1.02e-1)" "unprognostic (1.06e-2)" "unprognostic (1.63e-1)" "unprognostic (6.30e-2)" "unprognostic (3.48e-1)" "unprognostic (5.30e-2)" "unprognostic (1.88e-1)" CALHM3 "bA225H22.7, FAM26A" ENSG00000183128 "Calcium homeostasis modulator 3" Q86XJ0 10 103472804-103479240 "Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Sensory transduction, Taste, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Early spermatids: 4.8;Extravillous trophoblasts: 10.9;Late spermatids: 5.3" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bladder Urothelial Carcinoma (TCGA): 3.4;Ovary Serous Cystadenocarcinoma (TCGA): 1.7;Pancreatic Adenocarcinoma (TCGA): 3.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "pancreatic cancer: 5.3" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA018205 Uncertain NA NA "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" "HPA018205: " "unprognostic (6.86e-2)" "unprognostic (1.04e-1)" "unprognostic (4.41e-2)" "unprognostic (8.05e-3)" "unprognostic (2.95e-1)" CALHM4 "C6orf78, FAM26D, FLJ32239" ENSG00000164451 "Calcium homeostasis modulator family member 4" Q5JW98 6 116529013-116561127 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "placenta: 21.9" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 37.1;Migrating cytotrophoblasts: 20.1;Podocytes: 9.5;Syncytiotrophoblasts: 104.4" "Cell type enhanced" "Detected in single" "choroid plexus epithelial cell: 1.6" "Not detected" "Not detected" "Region enriched" "Detected in single" 4 "choroid plexus: 2.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "testis cancer: 1.6" "Kidney - Podocytes, Skin - Hair cortex cells, Skin - Inner root sheath cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA048014 Approved "Plasma membrane" NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 36: Choroid plexus - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 8 "Plasma membrane" "HPA048014: " CALHM5 "C6orf188, dJ493F7.3, FAM26E, MGC45451" ENSG00000178033 "Calcium homeostasis modulator family member 5" Q8N5C1 6 116511639-116524788 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 7.5" "Cell type enhanced" "Detected in some" "Fibroblasts: 5.8;Hepatic stellate cells: 6.5;Kupffer cells: 6.1;Late primary spermatocytes: 4.9;Pericytes: 11.3;Platelets: 29.6;Podocytes: 23.0;Schwann cells: 5.9;Vascular endothelial cells: 5.8;Vascular smooth muscle cells: 7.3" "Group enriched" "Detected in some" 15 "endothelial cell: 10.7;fibroblast: 14.1;pericyte: 11.0;vascular associated smooth muscle cell: 10.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adrenal gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA034969, HPA034970" Uncertain Approved "Golgi apparatus" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 9: Non-specific - Receptor signaling" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 110: Mural cells - ECM organization" 2 "Golgi apparatus" "HPA034969: , HPA034970: " "unprognostic (1.17e-1)" "unprognostic (1.55e-2)" "unprognostic (6.55e-2)" "unprognostic (3.08e-1)" "potential prognostic favorable (8.78e-6)" "unprognostic (4.27e-3)" "unprognostic (4.48e-2)" "unprognostic (1.62e-2)" "unprognostic (5.26e-2)" "unprognostic (3.50e-2)" "unprognostic (3.20e-2)" "unprognostic (1.02e-2)" "unprognostic (1.37e-2)" CALHM6 "C6orf187, dJ93H18.5, FAM26F, INAM, OTTHUMP00000017061, OTTHUMP00000017062, RP1-93H18.5" ENSG00000188820 "Calcium homeostasis modulator family member 6" Q5R3K3 6 116461370-116463771 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 130.4" "Cell type enriched" "Detected in some" 4 "Kupffer cells: 369.0" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 10.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "intermediate monocyte: 725.9;non-classical monocyte: 866.3" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 16.4" "Adrenal gland - Macrophages, Minor Salivary Gland - Macrophages, Spleen - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in single" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 22: Non-specific - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 2 "unprognostic (3.68e-1)" "unprognostic (2.68e-2)" "unprognostic (1.49e-2)" "unprognostic (6.68e-2)" "unprognostic (2.55e-1)" "unprognostic (1.78e-3)" "unprognostic (2.51e-1)" "unprognostic (2.11e-2)" "unprognostic (3.23e-1)" "unprognostic (1.88e-2)" "unprognostic (1.61e-1)" "unprognostic (1.88e-1)" "unprognostic (3.27e-1)" "unprognostic (6.68e-2)" "unprognostic (7.48e-2)" "unprognostic (2.63e-2)" "unprognostic (6.55e-2)" "unprognostic (1.63e-1)" "unprognostic (8.42e-2)" "unprognostic (3.38e-1)" "unprognostic (1.29e-1)" "unprognostic (2.04e-1)" "unprognostic (1.75e-2)" "unprognostic (1.06e-3)" "unprognostic (4.98e-2)" "unprognostic (1.51e-1)" "unprognostic (1.02e-2)" "unprognostic (2.62e-3)" "unprognostic (1.37e-1)" CALM1 "CALML2, CAMI, DD132, PHKD, PHKD1" ENSG00000198668 "Calmodulin 1" P0DP23 14 90396502-90408268 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Host-virus interaction" "Disease variant, FDA approved drug targets, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 6884.7;Respiratory ciliated cells: 2827.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "CAB018558, HPA044999" Supported Supported Cytosol NA NA 67000000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 14: Neurons - Synaptic function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 20: Non-specific - Transcription regulation" 234 Cytosol "CAB018558: , HPA044999: " "unprognostic (1.09e-1)" "unprognostic (2.96e-3)" "unprognostic (9.90e-2)" "unprognostic (1.09e-1)" "unprognostic (6.66e-2)" "unprognostic (5.51e-2)" "unprognostic (2.47e-1)" "unprognostic (3.81e-3)" "unprognostic (1.17e-3)" "potential prognostic unfavorable (7.46e-4)" "potential prognostic favorable (1.03e-7)" "unprognostic (2.18e-3)" "unprognostic (2.72e-2)" "potential prognostic unfavorable (2.01e-4)" "unprognostic (7.46e-2)" "unprognostic (1.95e-1)" "unprognostic (2.13e-1)" "unprognostic (2.89e-1)" "unprognostic (9.64e-2)" "unprognostic (1.34e-2)" "unprognostic (4.95e-2)" "unprognostic (2.64e-1)" "unprognostic (2.30e-1)" "unprognostic (3.48e-1)" "unprognostic (3.10e-1)" "unprognostic (5.19e-3)" "unprognostic (3.89e-2)" "unprognostic (7.67e-2)" "unprognostic (1.06e-2)" "unprognostic (1.71e-2)" "unprognostic (8.05e-2)" CALM2 "CAMII, PHKD, PHKD2" ENSG00000143933 "Calmodulin 2" P0DP24 2 47160084-47176921 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Disease variant, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fallopian secretory cells: 267.1;Fallopian tube ciliated cells: 428.6;Late primary spermatocytes: 266.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007790, HPA044999" Approved NA Yes "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 34: Non-specific - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 17: Non-specific - RNA processing" 112 "CAB007790: , HPA044999: " "unprognostic (6.97e-2)" "potential prognostic unfavorable (8.50e-4)" "unprognostic (1.07e-1)" "unprognostic (9.58e-2)" "unprognostic (1.25e-1)" "unprognostic (3.54e-2)" "unprognostic (1.04e-1)" "unprognostic (1.32e-1)" "unprognostic (6.92e-3)" "unprognostic (2.75e-2)" "potential prognostic favorable (3.25e-5)" "unprognostic (6.14e-2)" "unprognostic (1.55e-1)" "potential prognostic unfavorable (7.72e-7)" "unprognostic (3.04e-3)" "unprognostic (2.65e-1)" "unprognostic (6.76e-3)" "unprognostic (2.30e-2)" "unprognostic (1.42e-1)" "unprognostic (1.33e-1)" "unprognostic (3.96e-3)" "potential prognostic unfavorable (5.73e-4)" "unprognostic (7.06e-2)" "unprognostic (1.15e-1)" "unprognostic (2.49e-1)" "unprognostic (2.37e-3)" "unprognostic (3.03e-2)" "unprognostic (4.99e-3)" "unprognostic (1.72e-1)" "unprognostic (1.26e-2)" "unprognostic (1.02e-1)" CALM3 "PHKD, PHKD3" ENSG00000160014 "Calmodulin 3" P0DP25 19 46601074-46610782 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Disease variant, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1443.6" "Cell type enhanced" "Detected in all" "Early spermatids: 1768.9;Hofbauer cells: 1222.1;Late primary spermatocytes: 2115.5;Late spermatids: 3493.7;Megakaryocytes: 809.8;Platelets: 2983.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Spleen - Fibroblasts_1, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044999 Approved NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 14: Neurons - Synaptic function" "Cluster 4: Non-specific - Transcription" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 205 "HPA044999: " "unprognostic (2.84e-2)" "unprognostic (3.25e-2)" "unprognostic (1.61e-1)" "unprognostic (2.01e-3)" "unprognostic (2.58e-2)" "unprognostic (1.22e-1)" "unprognostic (1.29e-1)" "unprognostic (2.84e-1)" "unprognostic (5.31e-2)" "unprognostic (1.83e-1)" "potential prognostic favorable (1.78e-6)" "unprognostic (1.01e-1)" "unprognostic (1.56e-1)" "unprognostic (3.38e-2)" "unprognostic (2.57e-2)" "potential prognostic unfavorable (3.73e-6)" "unprognostic (8.97e-2)" "unprognostic (2.12e-1)" "unprognostic (1.17e-1)" "unprognostic (4.32e-3)" "unprognostic (3.23e-1)" "unprognostic (8.53e-2)" "unprognostic (3.27e-1)" "unprognostic (3.40e-2)" "unprognostic (3.19e-1)" "unprognostic (3.47e-1)" "unprognostic (2.74e-3)" "unprognostic (1.51e-1)" "unprognostic (2.88e-1)" "unprognostic (2.32e-2)" "unprognostic (3.10e-1)" CALML3 CLP ENSG00000178363 "Calmodulin like 3" P27482 10 5524961-5526771 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 307.0;esophagus: 823.1;skin 1: 277.9;vagina: 317.6" "Group enriched" "Detected in some" 5 "Esophageal apical cells: 4924.1;Esophageal basal cells: 1688.8;Esophageal suprabasal cells: 5507.7" "Not detected" "Not detected" "Group enriched" "Detected in many" 24 "Bladder Urothelial Carcinoma (TCGA): 222.3;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 551.9;Head and Neck Squamous Cell Carcinoma (TCGA): 593.7;Lung Squamous Cell Carcinoma (TCGA): 362.2;Skin Cutaneous Melanoma (TCGA): 171.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 96.9;Esophageal cancer: 92.1;head and neck cancer: 56.5" "Kidney - Proximal tubular cells, Minor Salivary Gland - Minor salivary gland basal cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells" "Not detected" "Not detected" "CAB010070, HPA044999" Approved NA NA 2400000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 57 "CAB010070: , HPA044999: " "unprognostic (1.90e-1)" "unprognostic (1.52e-3)" "unprognostic (4.54e-2)" "unprognostic (8.00e-2)" "unprognostic (4.20e-2)" "unprognostic (6.11e-2)" "unprognostic (4.06e-2)" "unprognostic (1.25e-1)" "unprognostic (5.61e-2)" "unprognostic (5.11e-2)" "unprognostic (8.00e-3)" "unprognostic (1.82e-1)" "unprognostic (3.08e-1)" "unprognostic (1.43e-1)" "unprognostic (1.05e-1)" "unprognostic (1.76e-1)" "unprognostic (1.69e-1)" "unprognostic (2.62e-1)" "unprognostic (3.68e-2)" CALML4 "MGC4809, NY-BR-20" ENSG00000129007 "Calmodulin like 4" Q96GE6 15 68190705-68206079 "Predicted intracellular proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 27.3;intestine: 36.3" "Cell type enhanced" "Detected in some" "Cholangiocytes: 6.6;Choroid plexus epithelial cells: 16.2;Colonocytes: 21.0;Endometrial ciliated cells: 13.5;Enteric transient amplifying cells: 8.9;Enterocytes: 18.0;Epididymal efferent duct absorptive cells: 11.5;Epididymal efferent duct ciliated cells: 15.1;Fallopian tube ciliated cells: 18.4;Kupffer cells: 11.3;Microglia: 9.6" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 33.5" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 4 "choroid plexus: 13.7" "Group enriched" "Detected in some" 40 "classical monocyte: 30.8;intermediate monocyte: 56.6;myeloid DC: 18.4;neutrophil: 18.1;non-classical monocyte: 66.4" "Group enriched" "Detected in many" 59 "dendritic cells: 18.4;granulocytes: 18.1;monocytes: 66.4" "Cancer enhanced" "Detected in all" "Myeloma: 61.4" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051109 Enhanced Approved "Nucleoplasm,Golgi apparatus,Cytosol" Yes No "Cluster 40: Monocytes - Innate immune response" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA051109: " "unprognostic (1.13e-1)" "unprognostic (3.94e-2)" "unprognostic (4.38e-2)" "unprognostic (2.92e-1)" "unprognostic (3.11e-2)" "unprognostic (5.16e-2)" "unprognostic (3.84e-1)" "unprognostic (6.59e-3)" "unprognostic (7.17e-2)" "unprognostic (6.16e-2)" "potential prognostic favorable (5.96e-5)" "unprognostic (4.20e-2)" "unprognostic (4.44e-2)" "unprognostic (4.96e-2)" "unprognostic (2.05e-1)" "unprognostic (6.56e-2)" "unprognostic (1.77e-1)" "unprognostic (2.00e-2)" "unprognostic (1.07e-2)" "unprognostic (1.89e-1)" "unprognostic (1.28e-2)" "unprognostic (1.78e-2)" "unprognostic (3.20e-2)" "unprognostic (5.76e-3)" "unprognostic (1.26e-2)" "unprognostic (1.32e-2)" "unprognostic (2.66e-1)" "unprognostic (1.39e-3)" "unprognostic (2.00e-1)" "unprognostic (3.15e-1)" "unprognostic (1.29e-1)" CALML5 CLSP ENSG00000178372 "Calmodulin like 5" Q9NZT1 10 5498697-5499570 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "skin 1: 2986.9" "Cell type enhanced" "Detected in some" "Breast secretory cells: 204.4;Esophageal apical cells: 921.1;Esophageal suprabasal cells: 168.0;Lacrimal acinar cells: 123.2;Salivary acinar cells: 609.5;Salivary myoepithelial cells: 142.8;Suprabasal keratinocytes: 332.6" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 303.9;Head and Neck Squamous Cell Carcinoma (TCGA): 323.1;Skin Cutaneous Melanoma (TCGA): 342.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 184.2;Esophageal cancer: 54.5" "Breast - Breast glandular cells (progenitors), Skin - Keratinocyte (granular)" "Not detected" "Not detected" HPA040725 Enhanced Approved "Plasma membrane,Cytosol" NA NA 42000000 "Cluster 9: Skin - Hair follicle development" "Cluster 70: DU4475 - Unknown function" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 34 "Plasma membrane, Cytosol" "HPA040725: " "unprognostic (3.56e-1)" "unprognostic (9.82e-3)" "unprognostic (1.94e-1)" "unprognostic (1.62e-2)" "potential prognostic favorable (2.75e-5)" "unprognostic (3.06e-2)" "unprognostic (2.31e-1)" "unprognostic (7.66e-2)" "unprognostic (8.39e-2)" "unprognostic (3.48e-1)" "unprognostic (9.84e-2)" "unprognostic (1.29e-2)" "unprognostic (2.97e-1)" "unprognostic (1.10e-1)" "unprognostic (3.32e-1)" "unprognostic (2.26e-1)" "unprognostic (1.70e-1)" CALML6 CAGLP ENSG00000169885 "Calmodulin like 6" Q8TD86 1 1915108-1917296 "Predicted intracellular proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 19 "skeletal muscle: 144.8;tongue: 102.3" "Cell type enriched" "Detected in some" 15 "Thymic myoid cells: 29.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" HPA005912 Supported "Nucleoplasm,Nuclear speckles,Nuclear bodies,Vesicles,Centrosome,Cytosol" NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 6: Leukemia - Signal transduction" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 2 "Nuclear speckles" "Nucleoplasm, Nuclear bodies, Vesicles, Centrosome, Cytosol" "HPA005912: " "unprognostic (1.12e-1)" "unprognostic (1.61e-1)" CALN1 CABP8 ENSG00000183166 "Calneuron 1" Q9BXU9 7 71779491-72447151 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 52.6;lymphoid tissue: 23.0" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 353.0;Bergmann glia: 548.8;Brain excitatory neurons: 897.4;Brain inhibitory neurons: 453.1;Differentiating spermatogonia: 455.0;Hematopoietic stem cells: 1502.2;Other brain neurons: 259.2;Pituitary stem cells: 454.0;Retinal amacrine cells: 338.7;Thymocytes: 239.7;Undifferentiated spermatogonia: 644.1" "Cell type enhanced" "Detected in all" "upper rhombic lip: 1901.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bone cancer: 4.1;Leukemia: 2.4;Myeloma: 8.5;Neuroblastoma: 2.4" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "HPA036278, HPA036708" Approved Uncertain "Vesicles,Plasma membrane" No No "Cluster 27: Cerebellum - Synaptic function" "Cluster 37: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 8 Vesicles "Plasma membrane" "HPA036278: , HPA036708: " "unprognostic (7.14e-2)" "unprognostic (5.64e-2)" "unprognostic (9.06e-2)" "unprognostic (1.37e-2)" "unprognostic (3.11e-2)" "unprognostic (1.05e-1)" CALR "cC1qR, CRT, FLJ26680, RO, SSA" ENSG00000179218 Calreticulin P27797 19 12938578-12944489 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1119.4;Extravillous trophoblasts: 2366.5;Syncytiotrophoblasts: 1173.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001513, HPA002242, CAB019952, CAB079775, CAB080301" Enhanced Supported "Endoplasmic reticulum" "Intracellular and membrane" Other NA NA 120000000 "Cluster 13: Non-specific - Mitochondria" "Cluster 70: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 8: Non-specific - Secretory pathway" 125 "Endoplasmic reticulum" "CAB001513: , CAB019952: , CAB079775: , CAB080301: , HPA002242: " "unprognostic (3.27e-2)" "unprognostic (8.65e-2)" "unprognostic (2.61e-2)" "unprognostic (1.09e-3)" "unprognostic (7.72e-2)" "unprognostic (8.82e-2)" "unprognostic (5.21e-2)" "unprognostic (7.91e-3)" "unprognostic (4.19e-2)" "unprognostic (3.57e-3)" "potential prognostic unfavorable (1.06e-4)" "unprognostic (1.03e-3)" "unprognostic (2.59e-2)" "unprognostic (2.93e-2)" "unprognostic (1.72e-2)" "unprognostic (1.73e-1)" "unprognostic (8.85e-3)" "unprognostic (3.34e-1)" "unprognostic (8.56e-2)" "potential prognostic favorable (6.30e-4)" "unprognostic (2.09e-1)" "unprognostic (1.15e-2)" "unprognostic (1.10e-1)" "unprognostic (1.55e-1)" "unprognostic (5.32e-2)" "unprognostic (1.19e-1)" "unprognostic (1.81e-2)" "unprognostic (6.63e-2)" "unprognostic (1.97e-1)" "unprognostic (1.34e-1)" "unprognostic (3.07e-1)" CALR3 "CRT2, CT93, FLJ25355, MGC26577" ENSG00000269058 "Calreticulin 3" Q96L12 19 16479061-16496167 "Plasma proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis" Chaperone Cardiomyopathy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 72 "testis: 61.9" "Cell type enhanced" "Detected in some" "Early primary spermatocytes: 2.3;Early spermatids: 48.1;Late primary spermatocytes: 15.5;Late spermatids: 11.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB025749, HPA043355, HPA048460" Enhanced "Intracellular and membrane" Other NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 57 "CAB025749: , HPA043355: , HPA048460: " CALU ENSG00000128595 Calumenin O43852 7 128739292-128773400 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 897.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006018, HPA071040" Supported Enhanced "Endoplasmic reticulum" "Intracellular and membrane" "No annotated function" NA NA 16000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 35: Non-specific - Mixed function" "Cluster 12: Non-specific - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 8: Non-specific - Secretory pathway" 25 "Endoplasmic reticulum" "HPA006018: , HPA071040: " "unprognostic (3.89e-1)" "unprognostic (2.60e-2)" "unprognostic (4.09e-3)" "unprognostic (8.50e-3)" "unprognostic (3.26e-1)" "unprognostic (2.24e-2)" "unprognostic (2.10e-1)" "potential prognostic unfavorable (9.48e-4)" "unprognostic (4.55e-2)" "potential prognostic unfavorable (3.50e-4)" "potential prognostic favorable (3.91e-4)" "potential prognostic unfavorable (3.06e-4)" "unprognostic (1.06e-3)" "validated prognostic unfavorable (4.21e-4)" "validated prognostic unfavorable (9.52e-5)" "unprognostic (1.24e-3)" "potential prognostic unfavorable (5.37e-4)" "unprognostic (1.96e-3)" "unprognostic (7.63e-2)" "unprognostic (8.66e-2)" "unprognostic (2.62e-3)" "unprognostic (5.17e-3)" "unprognostic (8.55e-2)" "unprognostic (1.95e-1)" "unprognostic (3.47e-1)" "unprognostic (1.64e-1)" "unprognostic (1.57e-1)" "unprognostic (1.82e-2)" "unprognostic (4.36e-1)" "unprognostic (8.43e-2)" "unprognostic (2.61e-1)" CALY "CALCYON, DRD1IP, NSG3" ENSG00000130643 "Calcyon neuron specific vesicular protein" Q9NYX4 10 133324072-133336935 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" Endocytosis "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "brain: 304.6;pituitary gland: 155.6" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 148.9;Brain excitatory neurons: 205.6;Brain inhibitory neurons: 304.0;Corticotrophs: 165.1;Ependymal cells: 195.5;Gonadotrophs: 416.4;Lactotrophs: 153.5;Other brain neurons: 787.3;Pancreatic islet cells: 256.7;Retinal bipolar cells: 98.7" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in some" 4 "Pancreatic Adenocarcinoma (TCGA): 30.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 1.5;Rhabdoid: 2.4" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Thyroid gland - Parafollicular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042283 Enhanced NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 98: Neurons - Neurotransmission & signaling" 1 "HPA042283: " "unprognostic (2.03e-2)" "unprognostic (5.73e-2)" "unprognostic (1.72e-1)" "unprognostic (3.61e-1)" "potential prognostic favorable (2.31e-4)" "unprognostic (6.04e-2)" CAMK1 "CaMKI, CaMKI-alpha" ENSG00000134072 "Calcium/calmodulin dependent protein kinase I" Q14012 3 9757347-9769992 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Differentiation, Neurogenesis" "Allosteric enzyme, Calmodulin-binding, Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 99.5" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 105.6;Megakaryocytes: 333.8;Sertoli cells: 76.6" "Cell type enhanced" "Detected in all" "hippocampal dentate gyrus: 132.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "eosinophil: 281.1" "Lineage enriched" "Detected in many" 6 "granulocytes: 281.1" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Spleen - Fibroblasts_1, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB031904, HPA051409" Approved Approved Cytosol NA NA 180000 "Cluster 45: Eosinophils - Unknown function" "Cluster 36: Brain & Liver - Signaling" "Cluster 51: Neurons - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 47: Platelets - Hemostasis" 15 Cytosol "CAB031904: , HPA051409: " "unprognostic (1.77e-2)" "unprognostic (2.79e-2)" "unprognostic (4.93e-3)" "unprognostic (1.59e-1)" "unprognostic (2.18e-1)" "unprognostic (3.05e-1)" "unprognostic (9.94e-2)" "unprognostic (6.17e-2)" "unprognostic (8.82e-2)" "potential prognostic unfavorable (4.62e-6)" "unprognostic (2.14e-2)" "unprognostic (2.56e-1)" "unprognostic (4.10e-2)" "unprognostic (2.11e-3)" "potential prognostic unfavorable (2.20e-7)" "unprognostic (4.14e-3)" "unprognostic (1.44e-1)" "unprognostic (1.54e-1)" "unprognostic (4.04e-2)" "unprognostic (2.60e-1)" "unprognostic (6.75e-2)" "unprognostic (5.53e-3)" "unprognostic (1.00e-2)" "unprognostic (8.86e-2)" "unprognostic (1.49e-2)" "unprognostic (6.68e-2)" "unprognostic (6.97e-2)" "unprognostic (7.57e-2)" "unprognostic (4.30e-2)" "unprognostic (1.20e-1)" "unprognostic (3.60e-1)" CAMK1D CKLiK ENSG00000183049 "Calcium/calmodulin dependent protein kinase ID" Q8IU85 10 12349547-12835545 "Enzymes, Plasma proteins, Predicted membrane proteins" "Inflammatory response, Neurogenesis" "Allosteric enzyme, Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 39.2;retina: 53.6" "Group enriched" "Detected in all" 4 "Cone photoreceptor cells: 4045.0;Neutrophils: 6615.0;Rod photoreceptor cells: 2980.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 64.4" "Lineage enriched" "Detected in all" 5 "granulocytes: 64.4" "Low cancer specificity" "Detected in many" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007266 Approved Approved "Nucleoplasm,Basal body,Cytosol" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 5 "Nucleoplasm, Cytosol" "Basal body" "HPA007266: " "unprognostic (2.10e-3)" "unprognostic (5.51e-2)" "unprognostic (1.36e-1)" "unprognostic (1.33e-1)" "unprognostic (3.88e-1)" "unprognostic (1.15e-1)" "unprognostic (4.98e-1)" "potential prognostic favorable (2.86e-4)" "unprognostic (3.63e-2)" "unprognostic (2.48e-3)" "potential prognostic favorable (3.94e-4)" "unprognostic (6.16e-3)" "unprognostic (1.62e-2)" "unprognostic (1.45e-2)" "potential prognostic favorable (4.96e-4)" "potential prognostic favorable (8.61e-6)" "unprognostic (2.43e-1)" "unprognostic (2.88e-1)" "potential prognostic favorable (3.46e-4)" "unprognostic (1.31e-2)" "unprognostic (3.17e-1)" "unprognostic (1.27e-1)" "unprognostic (3.97e-2)" "unprognostic (2.23e-1)" "unprognostic (4.44e-2)" "unprognostic (4.68e-2)" "unprognostic (3.96e-2)" "unprognostic (4.18e-2)" "unprognostic (1.93e-1)" "unprognostic (2.21e-2)" "unprognostic (6.28e-2)" CAMK1G "CLICKIII, dJ272L16.1, VWS1" ENSG00000008118 "Calcium/calmodulin dependent protein kinase IG" Q96NX5 1 209583714-209613939 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Allosteric enzyme, Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 48.1;ovary: 25.7" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 13.6;Brain inhibitory neurons: 22.9;Endometrial glandular cells: 13.0;Endometrial luminal cells: 20.4;Endometrial secretory cells: 25.3;Epididymal basal cells: 14.2;Epididymal principal cells: 8.6;Other brain neurons: 14.4;Ovarian stromal cells: 12.6;Retinal ganglion cells: 7.7;Salivary basal cells: 39.1;Salivary myoepithelial cells: 7.8;Somatotrophs: 13.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Bone cancer: 8.2;Sarcoma: 2.3;thyroid cancer: 2.3" "Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077157 Approved "Nucleoplasm,Primary cilium,Basal body,Cytosol" NA NA "Cluster 65: Brain - Transcription" "Cluster 53: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" 4 "Nucleoplasm, Cytosol" "Primary cilium, Basal body" "HPA077157: " "unprognostic (1.26e-1)" "unprognostic (4.77e-2)" "unprognostic (1.56e-1)" "unprognostic (4.22e-2)" "unprognostic (5.13e-2)" "unprognostic (6.32e-2)" "unprognostic (4.39e-2)" "unprognostic (1.74e-2)" "unprognostic (4.76e-3)" "unprognostic (4.65e-2)" CAMK2A "CAMKA, CaMKIIalpha, CaMKIINalpha, KIAA0968" ENSG00000070808 "Calcium/calmodulin dependent protein kinase II alpha" Q9UQM7 5 150219491-150290093 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 486.6;skeletal muscle: 153.5" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 227.9;Brain inhibitory neurons: 103.0;Corticotrophs: 33.6;Myonuclei: 148.3;Other brain neurons: 80.0;Pituitary stem cells: 39.3;Retinal amacrine cells: 53.9;Thymic myoid cells: 65.3" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in single" 14 "Glioblastoma Multiforme (TCGA): 12.3" "Group enriched" "Detected in all" 5 "amygdala: 795.7;basal ganglia: 786.5;cerebral cortex: 1817.1;hippocampal formation: 1345.8;white matter: 633.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 1.3" "Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Prostate - Fibroblasts, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 1422.5" "CAB004330, HPA051783, HPA051785, HPA053973" Supported Uncertain "Plasma membrane,Cell Junctions,Primary cilium tip,Primary cilium transition zone,Perinuclear theca,Calyx,Connecting piece,Principal piece,End piece" NA NA 110000 "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 35: Neurons - Synaptic function & neurogenesis" 85 "Plasma membrane, Primary cilium tip, Primary cilium transition zone, Principal piece" "Cell Junctions, Perinuclear theca, Calyx, Connecting piece, End piece" "CAB004330: , HPA051783: , HPA051785: , HPA053973: " "unprognostic (1.54e-1)" "unprognostic (1.73e-2)" "unprognostic (4.11e-2)" CAMK2B "CAM2, CAMK2, CAMKB, CaMKIIbeta" ENSG00000058404 "Calcium/calmodulin dependent protein kinase II beta" Q13554 7 44210019-44334577 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Actin-binding, Calmodulin-binding, Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 104.5;heart muscle: 62.4;skeletal muscle: 112.2;tongue: 57.4" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 159.6;Astrocytes: 106.4;Brain excitatory neurons: 292.9;Brain inhibitory neurons: 268.4;Cardiomyocytes: 116.7;Corticotrophs: 278.3;Epididymal principal cells: 117.8;Gonadotrophs: 166.0;Myonuclei: 151.5;Other brain neurons: 173.8;Retinal amacrine cells: 159.6;Retinal bipolar cells: 624.9;Retinal ganglion cells: 108.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 21.9;Thyroid Carcinoma (TCGA): 18.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 10.1" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Pancreas - Alpha cells, Pancreas - Beta cells, Pituitary gland - Corticotropes, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006849, HPA026307, HPA051783, HPA051785, HPA053973" Enhanced Supported Approved "Plasma membrane,Cell Junctions,Primary cilium tip,Primary cilium transition zone,Perinuclear theca,Calyx,Connecting piece,Principal piece,End piece" NA NA 140000 "Cluster 25: Non-specific - Basic cellular processes" "Cluster 51: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 33 "Plasma membrane, Primary cilium tip, Primary cilium transition zone, Principal piece" "Cell Junctions, Perinuclear theca, Calyx, Connecting piece, End piece" "CAB006849: , HPA026307: , HPA051783: , HPA051785: , HPA053973: " "unprognostic (4.27e-3)" "unprognostic (5.73e-3)" "unprognostic (1.12e-1)" "unprognostic (1.06e-1)" "unprognostic (2.06e-1)" "unprognostic (1.82e-2)" "unprognostic (1.08e-2)" "unprognostic (1.88e-1)" "potential prognostic favorable (4.68e-5)" "unprognostic (8.62e-2)" "potential prognostic favorable (1.40e-4)" "unprognostic (7.54e-2)" "unprognostic (1.64e-1)" "unprognostic (1.22e-1)" "unprognostic (2.73e-1)" "unprognostic (5.01e-2)" "unprognostic (3.25e-1)" "unprognostic (1.21e-2)" "unprognostic (2.68e-3)" "unprognostic (5.40e-2)" "unprognostic (8.07e-2)" "unprognostic (2.02e-2)" "unprognostic (1.57e-1)" CAMK2D CAMKD ENSG00000145349 "Calcium/calmodulin dependent protein kinase II delta" Q13557 4 113418054-113761927 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 123.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 966.3;Cone photoreceptor cells: 852.9;Myonuclei: 1130.4;Sertoli cells: 1041.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "HPA026281, HPA051783, HPA051785, HPA053973" Approved Approved "Plasma membrane,Cell Junctions,Primary cilium tip,Primary cilium transition zone,Perinuclear theca,Calyx,Connecting piece,Principal piece,End piece" NA NA 110000 "Cluster 18: Non-specific - Translation" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 36 "Plasma membrane, Primary cilium tip, Primary cilium transition zone, Principal piece" "Cell Junctions, Perinuclear theca, Calyx, Connecting piece, End piece" "HPA026281: , HPA051783: , HPA051785: , HPA053973: " "unprognostic (2.30e-1)" "unprognostic (6.09e-2)" "unprognostic (3.46e-1)" "unprognostic (4.41e-2)" "unprognostic (2.29e-2)" "unprognostic (2.89e-3)" "unprognostic (3.86e-1)" "unprognostic (1.92e-2)" "unprognostic (3.63e-1)" "unprognostic (2.54e-2)" "validated prognostic favorable (1.20e-4)" "validated prognostic favorable (6.77e-5)" "unprognostic (2.02e-1)" "unprognostic (2.11e-2)" "unprognostic (7.48e-2)" "unprognostic (1.74e-1)" "unprognostic (7.68e-2)" "unprognostic (6.86e-2)" "unprognostic (2.58e-2)" "unprognostic (1.92e-1)" "unprognostic (8.45e-3)" "unprognostic (3.83e-2)" "unprognostic (5.05e-1)" "unprognostic (2.63e-2)" "unprognostic (1.68e-1)" "unprognostic (3.46e-2)" "unprognostic (1.08e-1)" "unprognostic (1.65e-1)" "unprognostic (1.83e-1)" "unprognostic (3.61e-1)" "unprognostic (2.57e-1)" CAMK2G CAMKG ENSG00000148660 "Calcium/calmodulin dependent protein kinase II gamma" Q13555 10 73812501-73874591 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Neurogenesis" "Calmodulin-binding, Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 637.6;Bergmann glia: 356.5;Cone photoreceptor cells: 306.4;Cytotrophoblasts: 361.1;Neutrophils: 292.0" "Cell type enhanced" "Detected in all" "astrocyte: 808.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 128.4" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051783, HPA051785, HPA053973" Approved Approved "Plasma membrane,Cell Junctions,Primary cilium tip,Primary cilium transition zone,Perinuclear theca,Calyx,Connecting piece,Principal piece,End piece" NA NA 170000 "Cluster 21: Neutrophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 28: Astrocytes - Homeostasis & neuron support" 22 "Plasma membrane, Primary cilium tip, Primary cilium transition zone, Principal piece" "Cell Junctions, Perinuclear theca, Calyx, Connecting piece, End piece" "HPA051783: , HPA051785: , HPA053973: " "unprognostic (1.60e-2)" "unprognostic (1.19e-3)" "unprognostic (7.78e-2)" "unprognostic (1.09e-2)" "unprognostic (2.59e-1)" "unprognostic (7.67e-2)" "unprognostic (1.71e-1)" "unprognostic (4.13e-3)" "unprognostic (8.34e-2)" "unprognostic (2.30e-2)" "unprognostic (4.23e-3)" "unprognostic (1.33e-1)" "unprognostic (1.56e-1)" "unprognostic (3.15e-2)" "unprognostic (2.42e-1)" "unprognostic (3.29e-2)" "unprognostic (1.04e-1)" "unprognostic (3.23e-3)" "unprognostic (1.71e-1)" "unprognostic (1.48e-2)" "unprognostic (3.12e-2)" "unprognostic (4.02e-2)" "unprognostic (1.96e-1)" "unprognostic (4.88e-2)" "unprognostic (1.06e-2)" "unprognostic (1.14e-2)" "unprognostic (4.99e-1)" "unprognostic (1.88e-1)" "unprognostic (2.27e-2)" "unprognostic (1.23e-2)" "unprognostic (7.61e-2)" CAMK2N1 CaMKIINalpha ENSG00000162545 "Calcium/calmodulin dependent protein kinase II inhibitor 1" Q7Z7J9 1 20482391-20486210 "Predicted intracellular proteins" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 582.0" "Cell type enhanced" "Detected in many" "Colonocytes: 495.7;Epididymal clear cells: 528.7;Epididymal efferent duct absorptive cells: 300.0;Esophageal apical cells: 360.7;Goblet cells: 465.2;Ocular epithelial cells: 298.1;Oligodendrocytes: 288.0;Salivary duct cells: 470.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 1.6;MAIT T-cell: 1.1" "Lineage enhanced" "Detected in single" "T-cells: 1.6" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts, Lung - Fibroblasts_1, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA074969, HPA075200" Approved Approved "Primary cilium,Cytosol" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 2 Cytosol "Primary cilium" "HPA074969: , HPA075200: " "potential prognostic favorable (1.42e-4)" "unprognostic (1.22e-1)" "unprognostic (1.34e-2)" "unprognostic (2.34e-3)" "unprognostic (1.16e-1)" "unprognostic (1.68e-1)" "unprognostic (1.41e-2)" "unprognostic (6.79e-2)" "potential prognostic unfavorable (5.68e-7)" "unprognostic (3.25e-1)" "validated prognostic favorable (2.92e-7)" "validated prognostic favorable (9.58e-6)" "unprognostic (6.53e-2)" "validated prognostic unfavorable (1.19e-4)" "validated prognostic unfavorable (6.25e-5)" "unprognostic (1.02e-3)" "unprognostic (1.15e-1)" "unprognostic (5.35e-3)" "unprognostic (3.55e-3)" "unprognostic (8.33e-2)" "unprognostic (4.69e-2)" "unprognostic (1.53e-2)" "unprognostic (2.52e-2)" "unprognostic (9.41e-2)" "unprognostic (1.98e-2)" "unprognostic (1.91e-1)" "unprognostic (3.43e-1)" "unprognostic (6.13e-2)" "unprognostic (1.63e-1)" "unprognostic (1.55e-2)" "unprognostic (1.02e-1)" CAMK2N2 CaM-KIIN ENSG00000163888 "Calcium/calmodulin dependent protein kinase II inhibitor 2" Q96S95 3 184259213-184261553 "Predicted intracellular proteins" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 89.1;pancreas: 32.5;pituitary gland: 36.1" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 31.9;Brain excitatory neurons: 49.6;Brain inhibitory neurons: 54.3;Corticotrophs: 17.3;Gonadotrophs: 25.0;Lactotrophs: 18.9;Other brain neurons: 96.2;Pancreatic acinar cells: 57.9;Pancreatic islet cells: 34.6;Retinal amacrine cells: 53.1;Retinal horizontal cells: 50.1;Somatotrophs: 49.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 22.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enteroendocrine cells, Minor Salivary Gland - Minor salivary glandular cells, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050835, HPA075200" Approved Approved "Nucleoplasm,Centrosome,Basal body" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 45: Non-specific - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 98: Neurons - Neurotransmission & signaling" Nucleoplasm "Centrosome, Basal body" "HPA050835: , HPA075200: " "unprognostic (3.72e-2)" "unprognostic (7.16e-2)" "unprognostic (2.18e-1)" "unprognostic (1.64e-3)" "unprognostic (5.41e-2)" "unprognostic (1.38e-1)" "unprognostic (9.03e-2)" "unprognostic (8.27e-3)" "unprognostic (3.45e-2)" "unprognostic (1.68e-2)" "potential prognostic unfavorable (1.95e-4)" "unprognostic (4.82e-3)" "unprognostic (2.25e-3)" "unprognostic (5.51e-2)" "unprognostic (8.68e-2)" "potential prognostic unfavorable (1.47e-4)" "unprognostic (9.61e-2)" "unprognostic (4.73e-2)" "unprognostic (1.23e-2)" "unprognostic (1.45e-2)" "unprognostic (3.41e-1)" "unprognostic (2.70e-1)" "unprognostic (2.62e-1)" "unprognostic (3.82e-2)" "unprognostic (5.36e-2)" CAMK4 "CaMK-GR, CaMKIV" ENSG00000152495 "Calcium/calmodulin dependent protein kinase IV" Q16566 5 111223653-111494886 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Inflammatory response" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 52.7;lymphoid tissue: 51.6" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 138.3;Bergmann glia: 274.6;Brain excitatory neurons: 599.5;Brain inhibitory neurons: 523.8;Corticotrophs: 187.5;Early spermatids: 303.9;Innate lymphoid cells: 160.3;Late primary spermatocytes: 261.5;Late spermatids: 158.6;Oligodendrocyte progenitor cells: 190.4;Other brain neurons: 158.5;Retinal bipolar cells: 309.3;T-cells: 687.4;Thymocytes: 175.3" "Cell type enhanced" "Detected in all" "medium spiny neuron: 1197.4;upper rhombic lip: 1533.2" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in all" "cerebellum: 174.1" "Group enriched" "Detected in many" 4 "MAIT T-cell: 24.3;memory CD4 T-cell: 17.4;memory CD8 T-cell: 13.4;naive CD4 T-cell: 33.2;naive CD8 T-cell: 18.5;T-reg: 21.3" "Lineage enriched" "Detected in many" 23 "T-cells: 33.2" "Cancer enhanced" "Detected in many" "lymphoma: 17.8;Neuroblastoma: 27.8" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - Adrenal medulla cells, Breast - T-cells, Liver - Hepatic stellate cells, Minor Salivary Gland - T-cells, Stomach - T-cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004347, HPA011753, HPA017206" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Endoplasmic reticulum" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 27: Cerebellum - Synaptic function" "Cluster 15: Non-specific - Transcription" "Cluster 55: Lymphoma - Immune response" "Cluster 9: T-cells - Adaptive immunity: Regulation" 4 "Nucleoplasm, Nucleoli fibrillar center" "Endoplasmic reticulum" "CAB004347: , HPA011753: , HPA017206: " "unprognostic (5.68e-3)" "unprognostic (7.09e-2)" "unprognostic (3.97e-3)" "unprognostic (3.68e-3)" "unprognostic (3.79e-1)" "unprognostic (2.72e-1)" "unprognostic (2.09e-1)" "unprognostic (1.49e-1)" "unprognostic (1.53e-1)" "unprognostic (3.61e-2)" "unprognostic (1.65e-1)" "unprognostic (1.50e-1)" "unprognostic (1.55e-2)" "unprognostic (3.38e-1)" CAMKK1 "CAMKKA, DKFZp761M0423, MGC34095" ENSG00000004660 "Calcium/calmodulin dependent protein kinase kinase 1" Q8N5S9 17 3860315-3894891 "Enzymes, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 70.2" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 53.2;Brain excitatory neurons: 64.6;Lactotrophs: 63.2;Neutrophils: 56.5;Retinal bipolar cells: 80.9;Retinal ganglion cells: 73.4;Sertoli cells: 91.0;Somatotrophs: 99.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Liver - Vascular endothelial cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009111, HPA028062" Approved Approved Cytosol No No "Cluster 7: Non-specific - Innate immune response" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 9 Cytosol "CAB009111: , HPA028062: " "unprognostic (1.33e-1)" "unprognostic (3.46e-3)" "unprognostic (6.88e-2)" "unprognostic (4.69e-1)" "unprognostic (9.12e-2)" "unprognostic (1.28e-2)" "unprognostic (3.25e-2)" "unprognostic (1.45e-1)" "unprognostic (6.64e-2)" "unprognostic (1.42e-1)" "unprognostic (6.31e-2)" "unprognostic (7.65e-2)" "unprognostic (1.34e-2)" "unprognostic (2.73e-3)" "potential prognostic favorable (5.83e-4)" "unprognostic (1.53e-1)" "unprognostic (2.18e-1)" "unprognostic (1.20e-1)" "unprognostic (4.43e-2)" "unprognostic (3.73e-2)" "potential prognostic favorable (2.26e-4)" "unprognostic (5.21e-2)" "unprognostic (7.40e-2)" "unprognostic (9.22e-3)" "unprognostic (1.07e-2)" "unprognostic (1.65e-1)" "unprognostic (9.18e-2)" "unprognostic (1.49e-1)" "unprognostic (1.36e-1)" "unprognostic (8.03e-2)" CAMKK2 "CAMKK, CAMKKB, KIAA0787, MGC15254" ENSG00000110931 "Calcium/calmodulin dependent protein kinase kinase 2" Q96RR4 12 121237675-121298308 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "brain: 324.0" "Cell type enhanced" "Detected in many" "Late spermatids: 160.6;monocytes: 114.3;Neutrophil progenitors: 249.8;Neutrophils: 716.0" "Cell type enhanced" "Detected in all" "upper rhombic lip: 220.7" "Cancer enriched" "Detected in all" 4 "Prostate Adenocarcinoma (TCGA): 120.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 32.8;eosinophil: 62.2;intermediate monocyte: 42.3;myeloid DC: 15.9;neutrophil: 39.4;non-classical monocyte: 39.7" "Group enriched" "Detected in all" 5 "dendritic cells: 15.9;granulocytes: 62.2;monocytes: 42.3" "Low cancer specificity" "Detected in all" "Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017389, HPA063713" Approved Supported Supported Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 27: Cerebellum - Synaptic function" "Cluster 15: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 14 Cytosol "HPA017389: , HPA063713: " "unprognostic (7.87e-2)" "unprognostic (1.65e-1)" "unprognostic (3.00e-1)" "unprognostic (4.47e-2)" "unprognostic (9.93e-3)" "unprognostic (8.32e-2)" "unprognostic (2.71e-1)" "unprognostic (1.20e-2)" "unprognostic (2.38e-2)" "unprognostic (7.47e-2)" "unprognostic (1.24e-1)" "unprognostic (7.47e-2)" "unprognostic (4.41e-2)" "potential prognostic unfavorable (6.19e-4)" "unprognostic (7.05e-2)" "unprognostic (1.38e-1)" "unprognostic (5.97e-2)" "unprognostic (8.15e-2)" "unprognostic (2.25e-1)" "unprognostic (1.67e-3)" "unprognostic (1.87e-2)" "unprognostic (1.87e-2)" "unprognostic (3.12e-3)" "unprognostic (7.12e-2)" "unprognostic (8.59e-2)" "unprognostic (4.20e-3)" "unprognostic (1.44e-1)" "unprognostic (2.16e-1)" "unprognostic (5.35e-2)" "unprognostic (2.38e-1)" "unprognostic (3.03e-1)" CAMKMT "C2orf34, CLNMT" ENSG00000143919 "Calmodulin-lysine N-methyltransferase" Q7Z624 2 44361947-44772592 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067912 Supported Nucleoplasm,Nucleoli NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 36: Brain & Liver - Signaling" "Cluster 25: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 37: Neutrophil progenitors - Granulopoiesis" Nucleoplasm Nucleoli "HPA067912: " "unprognostic (1.54e-1)" "unprognostic (2.35e-1)" "unprognostic (2.26e-2)" "unprognostic (2.23e-1)" "unprognostic (3.00e-2)" "unprognostic (1.13e-1)" "unprognostic (1.09e-1)" "unprognostic (1.20e-1)" "unprognostic (4.60e-2)" "unprognostic (3.03e-3)" "unprognostic (1.85e-2)" "unprognostic (2.16e-1)" "unprognostic (3.78e-3)" "potential prognostic unfavorable (1.83e-4)" "unprognostic (7.12e-2)" "unprognostic (4.96e-2)" "unprognostic (5.29e-3)" "unprognostic (3.03e-2)" "unprognostic (1.87e-1)" "unprognostic (1.17e-1)" "unprognostic (6.22e-2)" "unprognostic (3.95e-1)" "unprognostic (3.33e-2)" "unprognostic (5.11e-2)" "unprognostic (9.42e-2)" "unprognostic (2.05e-1)" "unprognostic (9.69e-2)" "unprognostic (1.11e-1)" "unprognostic (1.31e-1)" "unprognostic (1.53e-2)" CAMKV "MGC8407, VACAMKL" ENSG00000164076 "CaM kinase like vesicle associated" Q8NCB2 3 49857988-49869935 "Enzymes, Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 27 "brain: 220.1" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 45.8;Brain inhibitory neurons: 84.9;Early spermatids: 7.4;Late spermatids: 15.4;Oligodendrocytes: 7.7;Other brain neurons: 36.4;Retinal amacrine cells: 42.1" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in some" 10 "Glioblastoma Multiforme (TCGA): 7.4;Testicular Germ Cell Tumor (TCGA): 9.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Neuroblastoma: 23.5" "Adrenal gland - Adrenal medulla cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007656, CAB034931" Enhanced Supported Approved "Nucleoplasm,Cytokinetic bridge" Yes NA "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 35: Neurons - Synaptic function & neurogenesis" 43 Nucleoplasm "Cytokinetic bridge" "CAB034931: , HPA007656: " "unprognostic (3.31e-1)" "potential prognostic favorable (9.55e-5)" "unprognostic (9.60e-2)" CAMLG "CAML, GET2" ENSG00000164615 "Calcium modulating ligand" P49069 5 134738495-134752157 "Essential proteins, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "ER-Golgi transport, Host-virus interaction, Transport" "Congenital disorder of glycosylation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 836.8;Late primary spermatocytes: 668.9;Late spermatids: 2733.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052636, HPA056472" Approved Uncertain Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 14: Neurons - Synaptic function" "Cluster 25: Non-specific - Ribosome" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 38 Vesicles "Nucleoplasm, Nucleoli" "HPA052636: , HPA056472: " "unprognostic (6.16e-3)" "unprognostic (1.14e-1)" "unprognostic (6.72e-2)" "unprognostic (4.37e-2)" "unprognostic (7.98e-2)" "unprognostic (7.27e-2)" "unprognostic (7.28e-2)" "unprognostic (1.73e-1)" "unprognostic (4.10e-3)" "unprognostic (1.25e-2)" "potential prognostic favorable (5.43e-5)" "unprognostic (4.39e-2)" "unprognostic (2.71e-3)" "unprognostic (2.64e-2)" "unprognostic (1.95e-1)" "unprognostic (5.62e-2)" "unprognostic (1.65e-1)" "unprognostic (3.60e-2)" "unprognostic (1.55e-1)" "unprognostic (3.78e-2)" "unprognostic (1.52e-2)" "unprognostic (1.33e-3)" "unprognostic (1.66e-2)" "unprognostic (1.08e-2)" "unprognostic (3.84e-1)" "unprognostic (2.79e-2)" "unprognostic (3.05e-1)" "unprognostic (1.78e-2)" "unprognostic (1.17e-1)" "unprognostic (1.34e-1)" "unprognostic (1.03e-1)" CAMP "CAP18, FALL-39, FALL39, LL37" ENSG00000164047 "Cathelicidin antimicrobial peptide" P49913 3 48223347-48225491 "Plasma proteins, Predicted secreted proteins, Transporters" "Immunity, Innate immunity" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "bone marrow: 2752.0" "Group enriched" "Detected in some" 8 "Epididymal principal cells: 2706.7;Neutrophil progenitors: 1430.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 14.7" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "eosinophil: 84.7;neutrophil: 337.5" "Lineage enriched" "Detected in many" 12 "granulocytes: 337.5" "Cancer enhanced" "Detected in some" "breast cancer: 3.7;lymphoma: 11.9" "Minor Salivary Gland - Minor salivary glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB015949, CAB016522, HPA029874" Enhanced "Secreted to blood" Immunity NA NA 617000000 36000000 "Cluster 7: Non-specific - Innate immune response" "Cluster 15: Bone marrow - Innate immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" 2 "CAB015949: , CAB016522: , HPA029874: " "unprognostic (5.59e-2)" "unprognostic (7.66e-2)" "potential prognostic favorable (3.20e-4)" "unprognostic (2.57e-2)" "unprognostic (4.71e-2)" "potential prognostic favorable (1.08e-4)" "unprognostic (4.82e-2)" "unprognostic (3.35e-3)" "unprognostic (1.07e-1)" "unprognostic (3.34e-1)" "unprognostic (3.41e-1)" "unprognostic (7.47e-2)" "unprognostic (7.93e-2)" "unprognostic (9.66e-3)" "unprognostic (1.14e-2)" CAMSAP1 "DKFZp434F195, FLJ31228" ENSG00000130559 "Calmodulin regulated spectrin associated protein 1" Q5T5Y3 9 135808487-135907546 "Predicted intracellular proteins" "Disease variant, Intellectual disability, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 97.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 370.6;Epididymal basal cells: 183.9;Ocular epithelial cells: 230.7;Rod photoreceptor cells: 493.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020527, HPA024161" Approved Supported "Mitotic spindle,Cytosol" Yes No "Cluster 13: Non-specific - Mitochondria" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 79: Photoreceptor cells - Phototransduction" 9 "Mitotic spindle, Cytosol" "HPA020527: , HPA024161: " "unprognostic (2.01e-1)" "unprognostic (1.92e-3)" "unprognostic (2.14e-2)" "unprognostic (1.63e-1)" "unprognostic (2.04e-1)" "potential prognostic unfavorable (3.52e-4)" "unprognostic (3.95e-1)" "potential prognostic favorable (3.22e-4)" "unprognostic (4.17e-2)" "unprognostic (2.85e-2)" "potential prognostic favorable (5.10e-7)" "unprognostic (2.83e-3)" "unprognostic (1.06e-1)" "unprognostic (3.30e-3)" "unprognostic (1.82e-1)" "unprognostic (3.03e-1)" "unprognostic (5.65e-3)" "unprognostic (2.28e-1)" "unprognostic (8.46e-3)" "unprognostic (9.44e-2)" "unprognostic (4.82e-2)" "unprognostic (6.23e-2)" "unprognostic (5.18e-3)" "unprognostic (8.13e-2)" "unprognostic (3.17e-2)" "unprognostic (3.04e-3)" "unprognostic (3.12e-1)" "unprognostic (1.39e-1)" "unprognostic (5.75e-1)" "unprognostic (1.30e-2)" "unprognostic (2.11e-1)" CAMSAP2 "CAMSAP1L1, KIAA1078" ENSG00000118200 "Calmodulin regulated spectrin associated protein family member 2" Q08AD1 1 200738893-200860704 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026304, HPA026511, HPA027302" Enhanced Supported "Golgi apparatus,Microtubule ends,Primary cilium,Basal body,Cytosol" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 34: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 27 "Microtubule ends" "Golgi apparatus, Primary cilium, Basal body, Cytosol" "HPA026304: , HPA026511: , HPA027302: " "unprognostic (1.87e-1)" "unprognostic (7.06e-2)" "unprognostic (3.73e-3)" "unprognostic (1.37e-1)" "unprognostic (2.98e-2)" "unprognostic (1.77e-2)" "unprognostic (5.23e-2)" "unprognostic (1.03e-1)" "potential prognostic unfavorable (1.16e-4)" "unprognostic (1.10e-3)" "unprognostic (3.03e-2)" "unprognostic (1.19e-3)" "potential prognostic unfavorable (3.22e-4)" "potential prognostic unfavorable (7.94e-4)" "unprognostic (6.25e-3)" "unprognostic (3.64e-2)" "unprognostic (1.28e-1)" "unprognostic (1.46e-1)" "unprognostic (2.26e-3)" "unprognostic (1.88e-2)" "unprognostic (6.67e-2)" "unprognostic (3.62e-2)" "unprognostic (1.99e-1)" "unprognostic (2.49e-2)" "unprognostic (1.21e-1)" "unprognostic (8.12e-3)" "unprognostic (2.43e-1)" "unprognostic (2.38e-3)" "unprognostic (1.69e-1)" CAMSAP3 "KIAA1543, Nezha, PPP1R80" ENSG00000076826 "Calmodulin regulated spectrin associated protein family member 3" Q9P1Y5 19 7595863-7618304 "Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 59.9" "Cell type enhanced" "Detected in many" "Breast lactating cells: 84.0;Esophageal apical cells: 125.6;Foveolar cells: 54.0;Lacrimal acinar cells: 54.3;Sertoli cells: 55.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043830 Enhanced NA NA "Cluster 2: Non-specific - Mixed function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 31 "HPA043830: " "unprognostic (4.18e-2)" "unprognostic (8.24e-2)" "unprognostic (7.35e-2)" "unprognostic (1.45e-2)" "unprognostic (1.43e-1)" "unprognostic (1.90e-1)" "unprognostic (6.43e-2)" "unprognostic (3.32e-3)" "unprognostic (1.60e-2)" "potential prognostic favorable (9.05e-8)" "unprognostic (4.14e-2)" "potential prognostic favorable (4.79e-4)" "unprognostic (8.83e-3)" "unprognostic (3.84e-3)" "unprognostic (2.49e-1)" "unprognostic (1.05e-1)" "unprognostic (5.77e-2)" "unprognostic (1.60e-1)" "unprognostic (6.00e-2)" "unprognostic (3.11e-2)" "unprognostic (5.17e-2)" "unprognostic (6.66e-2)" "unprognostic (2.74e-2)" "unprognostic (2.30e-1)" "unprognostic (8.48e-2)" "unprognostic (1.77e-2)" "unprognostic (1.28e-1)" "unprognostic (9.70e-2)" "unprognostic (1.35e-3)" CAMTA1 KIAA0833 ENSG00000171735 "Calmodulin binding transcription activator 1" Q9Y6Y1 1 6785454-7769706 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Megakaryocytes: 1075.6;Retinal ganglion cells: 1035.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036342, HPA036343" Approved Approved "Nucleoli,Basal body,Cytosol" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 37: Non-specific - mRNA processing" "Cluster 109: Neurons - Neuronal signaling" Cytosol "Nucleoli, Basal body" "HPA036342: , HPA036343: " "unprognostic (1.71e-1)" "unprognostic (1.51e-1)" "unprognostic (1.00e-1)" "unprognostic (2.60e-2)" "unprognostic (5.97e-2)" "unprognostic (1.20e-1)" "unprognostic (1.39e-1)" "potential prognostic favorable (2.10e-4)" "unprognostic (4.97e-2)" "unprognostic (1.90e-1)" "unprognostic (1.83e-3)" "unprognostic (3.97e-2)" "unprognostic (7.22e-3)" "potential prognostic unfavorable (3.92e-4)" "unprognostic (2.87e-3)" "unprognostic (3.68e-3)" "unprognostic (3.95e-1)" "unprognostic (1.74e-1)" "unprognostic (3.79e-2)" "unprognostic (2.55e-2)" "unprognostic (1.19e-1)" "unprognostic (1.06e-1)" "unprognostic (4.16e-2)" "unprognostic (1.35e-1)" "unprognostic (2.00e-1)" "unprognostic (1.92e-1)" "unprognostic (1.79e-1)" "unprognostic (3.32e-1)" "unprognostic (1.36e-1)" "unprognostic (3.37e-1)" "unprognostic (4.59e-2)" CAMTA2 KIAA0909 ENSG00000108509 "Calmodulin binding transcription activator 2" O94983 17 4967992-4987675 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 84.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027835, HPA051147" Supported "Nucleoplasm,Vesicles,Actin filaments,Mitochondria,Cytosol" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 1 Nucleoplasm "Vesicles, Actin filaments, Mitochondria, Cytosol" "HPA027835: , HPA051147: " "unprognostic (9.47e-2)" "unprognostic (1.14e-1)" "unprognostic (1.22e-1)" "unprognostic (2.90e-2)" "unprognostic (2.23e-1)" "unprognostic (6.86e-2)" "unprognostic (1.22e-1)" "unprognostic (3.05e-1)" "unprognostic (7.70e-2)" "unprognostic (1.51e-2)" "validated prognostic favorable (1.10e-5)" "validated prognostic favorable (6.45e-5)" "potential prognostic favorable (1.28e-4)" "unprognostic (1.11e-1)" "unprognostic (4.98e-3)" "unprognostic (4.11e-2)" "unprognostic (5.45e-2)" "unprognostic (2.19e-2)" "unprognostic (2.73e-1)" "unprognostic (9.24e-2)" "unprognostic (8.08e-3)" "potential prognostic favorable (3.11e-4)" "unprognostic (1.61e-2)" "unprognostic (2.40e-1)" "unprognostic (7.01e-2)" "unprognostic (1.47e-1)" "unprognostic (1.12e-1)" "unprognostic (1.21e-1)" "unprognostic (1.41e-1)" "unprognostic (3.01e-2)" "unprognostic (3.98e-1)" CAND1 "DKFZp434M1414, KIAA0829, TIP120, TIP120A" ENSG00000111530 "Cullin associated and neddylation dissociated 1" Q86VP6 12 67269358-67319953 "Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells, Skeletal muscle - Endothelial cells, Skin - Mitotic cells (Skin)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055748, HPA062833, HPA069053" Approved Supported "Nucleoplasm,Golgi apparatus,Cytosol" No No 5200000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 98 "Golgi apparatus, Cytosol" Nucleoplasm "HPA055748: , HPA062833: , HPA069053: " "unprognostic (1.15e-1)" "unprognostic (1.83e-2)" "unprognostic (3.31e-2)" "unprognostic (5.34e-2)" "unprognostic (6.46e-3)" "unprognostic (2.58e-1)" "unprognostic (3.32e-1)" "unprognostic (4.87e-3)" "unprognostic (1.74e-1)" "unprognostic (3.36e-3)" "potential prognostic favorable (5.34e-7)" "unprognostic (3.41e-2)" "unprognostic (1.90e-2)" "potential prognostic unfavorable (1.45e-4)" "unprognostic (1.01e-2)" "potential prognostic unfavorable (5.54e-6)" "unprognostic (1.80e-2)" "unprognostic (3.65e-2)" "unprognostic (4.18e-1)" "unprognostic (2.19e-1)" "potential prognostic unfavorable (8.37e-4)" "unprognostic (2.45e-3)" "unprognostic (1.24e-1)" "unprognostic (6.10e-2)" "unprognostic (3.30e-2)" "unprognostic (2.74e-2)" "unprognostic (1.01e-1)" "unprognostic (2.11e-1)" "unprognostic (3.80e-1)" "unprognostic (2.25e-1)" "unprognostic (1.34e-1)" CAND2 "KIAA0667, TIP120B, Tp120b" ENSG00000144712 "Cullin associated and neddylation dissociated 2 (putative)" O75155 3 12796472-12834804 "Predicted intracellular proteins" "Transcription, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 125.9;tongue: 33.7" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 27.4;Cardiomyocytes: 61.5;Corticotrophs: 29.7;Myonuclei: 195.2;Other brain neurons: 25.3;Retinal amacrine cells: 27.6;Sertoli cells: 37.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Cardiomyocytes, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005777 Approved Approved "Nuclear bodies,Cytosol" NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 14: Neurons - Synaptic function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 12 "Nuclear bodies" Cytosol "HPA005777: " "unprognostic (3.37e-1)" "unprognostic (5.76e-2)" "unprognostic (8.02e-2)" "unprognostic (8.53e-3)" "unprognostic (1.94e-3)" "unprognostic (1.32e-1)" "unprognostic (2.59e-2)" "unprognostic (5.89e-2)" "unprognostic (1.68e-1)" "unprognostic (4.34e-2)" "unprognostic (2.13e-1)" "unprognostic (3.60e-1)" "unprognostic (2.17e-1)" "unprognostic (5.40e-2)" "unprognostic (9.38e-2)" "unprognostic (1.57e-2)" "unprognostic (2.48e-1)" "unprognostic (9.74e-3)" "unprognostic (1.12e-1)" "unprognostic (3.03e-1)" "unprognostic (1.68e-1)" "unprognostic (4.23e-2)" "unprognostic (1.07e-2)" "unprognostic (2.68e-1)" "unprognostic (8.35e-3)" "unprognostic (2.18e-1)" CANT1 "SCAN-1, SHAPY" ENSG00000171302 "Calcium activated nucleotidase 1" Q8WVQ1 17 78991716-79009867 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 248.7;Colonocytes: 134.8;Esophageal apical cells: 277.0;Goblet cells: 168.1;Neutrophils: 102.7;Prostatic glandular cells: 106.7;Syncytiotrophoblasts: 132.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019627, HPA019639, HPA022818" Enhanced Supported "Golgi apparatus" NA Yes 1200000 "Cluster 21: Neutrophils - Unknown function" "Cluster 17: Intestine - Digestion" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 27: Breast cancer - Unknown function" "Cluster 70: Intestinal goblet cells - Mucin production" 11 "Golgi apparatus" "HPA019627: , HPA019639: , HPA022818: " "unprognostic (3.26e-1)" "unprognostic (1.12e-2)" "unprognostic (2.58e-1)" "potential prognostic unfavorable (1.78e-4)" "unprognostic (3.42e-2)" "unprognostic (3.01e-1)" "unprognostic (2.28e-2)" "unprognostic (6.54e-2)" "unprognostic (1.90e-1)" "potential prognostic unfavorable (1.84e-5)" "unprognostic (3.05e-3)" "potential prognostic unfavorable (2.46e-4)" "unprognostic (3.22e-2)" "validated prognostic unfavorable (2.57e-4)" "validated prognostic unfavorable (1.53e-5)" "unprognostic (2.39e-3)" "unprognostic (2.55e-2)" "potential prognostic unfavorable (7.49e-5)" "unprognostic (1.49e-2)" "unprognostic (1.43e-1)" "unprognostic (9.61e-2)" "unprognostic (3.65e-2)" "unprognostic (5.39e-2)" "unprognostic (3.70e-1)" "unprognostic (5.73e-2)" "unprognostic (8.48e-3)" "unprognostic (1.76e-1)" "unprognostic (3.88e-2)" "unprognostic (1.37e-1)" "unprognostic (1.93e-1)" "unprognostic (5.74e-2)" CANX "CNX, IP90, P90" ENSG00000127022 Calnexin P27824 5 179678628-179731641 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 5 "Late spermatids: 1223.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004738, HPA009433, HPA009696" Enhanced Enhanced "Endoplasmic reticulum" NA NA 12000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 785 "Endoplasmic reticulum" "CAB004738: , HPA009433: , HPA009696: " "unprognostic (2.09e-1)" "unprognostic (1.68e-1)" "unprognostic (1.20e-1)" "unprognostic (1.19e-1)" "unprognostic (3.45e-2)" "unprognostic (1.09e-2)" "unprognostic (2.07e-1)" "potential prognostic unfavorable (1.58e-5)" "unprognostic (8.41e-2)" "unprognostic (1.32e-2)" "unprognostic (4.08e-3)" "unprognostic (1.36e-1)" "unprognostic (1.40e-3)" "unprognostic (1.95e-1)" "unprognostic (1.49e-2)" "unprognostic (2.85e-1)" "unprognostic (3.53e-2)" "unprognostic (3.97e-1)" "unprognostic (4.47e-2)" "unprognostic (1.50e-2)" "potential prognostic unfavorable (3.93e-4)" "unprognostic (3.76e-1)" "unprognostic (3.10e-2)" "unprognostic (1.82e-1)" "unprognostic (1.96e-1)" "unprognostic (2.79e-1)" "unprognostic (8.73e-2)" "unprognostic (3.47e-1)" "unprognostic (8.26e-2)" "unprognostic (3.46e-3)" "unprognostic (7.34e-2)" CAP1 CAP ENSG00000131236 "Cyclase associated actin cytoskeleton regulatory protein 1" Q01518 1 40040233-40072649 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 697.3;Late spermatids: 650.1;Megakaryocytes: 933.4;Neutrophil progenitors: 1261.9;Neutrophils: 1953.7;Platelets: 1016.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030124 Approved Approved Cytosol NA NA 77000000 "Cluster 25: Non-specific - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 27: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 26 Cytosol "HPA030124: " "unprognostic (2.97e-1)" "unprognostic (1.65e-1)" "unprognostic (3.83e-3)" "potential prognostic unfavorable (5.53e-5)" "unprognostic (2.81e-3)" "unprognostic (4.64e-1)" "unprognostic (1.06e-1)" "unprognostic (5.66e-1)" "unprognostic (5.03e-2)" "unprognostic (1.53e-3)" "potential prognostic favorable (3.69e-8)" "unprognostic (1.55e-2)" "unprognostic (1.36e-1)" "potential prognostic unfavorable (1.51e-7)" "unprognostic (2.16e-2)" "unprognostic (1.11e-1)" "potential prognostic unfavorable (2.97e-4)" "unprognostic (5.29e-3)" "potential prognostic unfavorable (2.94e-5)" "unprognostic (3.14e-2)" "unprognostic (9.86e-3)" "unprognostic (8.27e-3)" "unprognostic (1.57e-1)" "unprognostic (3.34e-2)" "unprognostic (5.80e-2)" "unprognostic (4.67e-1)" "unprognostic (2.43e-1)" "unprognostic (6.27e-2)" "unprognostic (4.05e-1)" "unprognostic (1.65e-1)" "unprognostic (3.78e-2)" CAP2 ENSG00000112186 "Cyclase associated actin cytoskeleton regulatory protein 2" P40123 6 17393595-17557780 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 539.5;tongue: 291.8" "Cell type enriched" "Detected in many" 5 "Myonuclei: 2274.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Testis - Peritubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050530, HPA054147" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 51: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 27 "Nucleoplasm, Cytosol" "Plasma membrane" "HPA050530: , HPA054147: " "unprognostic (4.55e-1)" "unprognostic (1.43e-1)" "unprognostic (7.89e-2)" "unprognostic (2.35e-3)" "unprognostic (5.25e-3)" "unprognostic (1.74e-1)" "unprognostic (3.76e-1)" "unprognostic (5.71e-2)" "unprognostic (1.30e-2)" "unprognostic (3.68e-1)" "potential prognostic favorable (7.39e-6)" "unprognostic (7.93e-2)" "unprognostic (4.81e-1)" "unprognostic (3.79e-2)" "unprognostic (2.97e-2)" "unprognostic (9.32e-3)" "unprognostic (2.52e-1)" "unprognostic (6.40e-2)" "unprognostic (2.03e-2)" "unprognostic (4.28e-1)" "unprognostic (2.92e-2)" "unprognostic (9.83e-2)" "unprognostic (9.72e-2)" "unprognostic (2.26e-1)" "unprognostic (2.42e-1)" "unprognostic (1.05e-1)" "unprognostic (4.89e-2)" "unprognostic (1.58e-3)" "unprognostic (1.15e-1)" "unprognostic (3.22e-1)" "unprognostic (2.97e-1)" CAPG "AFCP, MCP" ENSG00000042493 "Capping actin protein, gelsolin like" P40121 2 85394753-85418432 "Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 718.6;Esophageal basal cells: 355.0;Esophageal suprabasal cells: 617.5;Extravillous trophoblasts: 508.5;Hofbauer cells: 508.0;Mast cells: 521.0;Urothelial cells: 332.7" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 47.4;leukocyte: 19.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 1142.1;classical monocyte: 1141.1;eosinophil: 714.5;intermediate monocyte: 431.9;memory B-cell: 577.9;myeloid DC: 1364.5;naive B-cell: 520.3;NK-cell: 606.9;plasmacytoid DC: 961.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adrenal gland - Macrophages, Lung - Macrophages, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018843, HPA019080, HPA019092" Enhanced Supported "Nucleoplasm,Mitotic chromosome" Yes No 3400000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 5 Nucleoplasm "Mitotic chromosome" "HPA018843: , HPA019080: , HPA019092: " "unprognostic (2.32e-1)" "unprognostic (1.72e-1)" "unprognostic (1.28e-1)" "unprognostic (2.12e-1)" "unprognostic (1.15e-1)" "unprognostic (1.85e-2)" "unprognostic (1.18e-2)" "unprognostic (1.49e-2)" "unprognostic (7.79e-2)" "unprognostic (2.98e-3)" "unprognostic (6.77e-2)" "unprognostic (1.11e-2)" "unprognostic (1.76e-3)" "potential prognostic unfavorable (4.65e-5)" "unprognostic (4.60e-1)" "unprognostic (8.93e-2)" "unprognostic (4.04e-2)" "unprognostic (1.33e-1)" "unprognostic (1.20e-2)" "unprognostic (8.03e-2)" "unprognostic (1.58e-1)" "unprognostic (3.68e-3)" "unprognostic (2.21e-2)" "unprognostic (1.71e-1)" "unprognostic (5.20e-2)" "unprognostic (3.74e-1)" "unprognostic (4.02e-2)" "unprognostic (1.11e-1)" "unprognostic (5.05e-2)" "unprognostic (1.07e-2)" "unprognostic (2.65e-2)" CAPN1 "CANP, CANPL1, muCANP, muCL" ENSG00000014216 "Calpain 1" P07384 11 65180566-65212006 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 267.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 293.2;Esophageal apical cells: 893.0;Esophageal suprabasal cells: 470.9;Platelets: 663.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells, Skin - Keratinocyte (other), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005992 Enhanced Supported Cytosol NA NA 14000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 36 Cytosol "HPA005992: " "unprognostic (1.77e-1)" "unprognostic (4.11e-2)" "unprognostic (2.81e-1)" "unprognostic (5.88e-3)" "unprognostic (1.76e-1)" "unprognostic (1.02e-1)" "unprognostic (1.92e-1)" "unprognostic (1.75e-1)" "unprognostic (7.34e-2)" "unprognostic (3.16e-1)" "potential prognostic favorable (1.38e-8)" "unprognostic (2.44e-1)" "unprognostic (2.72e-2)" "unprognostic (4.24e-2)" "potential prognostic unfavorable (9.77e-4)" "unprognostic (2.59e-2)" "unprognostic (5.79e-3)" "unprognostic (8.47e-2)" "unprognostic (1.05e-1)" "unprognostic (5.36e-2)" "unprognostic (1.84e-1)" "unprognostic (2.44e-3)" "unprognostic (2.52e-2)" "unprognostic (2.44e-1)" "unprognostic (5.47e-2)" "unprognostic (3.23e-1)" "unprognostic (1.83e-1)" "unprognostic (7.40e-2)" "unprognostic (1.86e-1)" "unprognostic (1.58e-1)" "unprognostic (2.81e-1)" CAPN10 ENSG00000142330 "Calpain 10" Q9HC96 2 240586734-240617705 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Retinal horizontal cells: 44.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004170 Approved Approved Mitochondria,Cytosol NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 51: Secretory epithelial cells - Mixed function" 15 "Mitochondria, Cytosol" "HPA004170: " "unprognostic (2.25e-2)" "unprognostic (5.39e-2)" "unprognostic (2.55e-2)" "unprognostic (5.23e-2)" "unprognostic (8.99e-2)" "unprognostic (1.09e-2)" "unprognostic (4.91e-2)" "unprognostic (2.08e-1)" "unprognostic (1.40e-2)" "unprognostic (7.46e-2)" "potential prognostic unfavorable (9.32e-8)" "unprognostic (2.96e-1)" "unprognostic (3.41e-2)" "potential prognostic unfavorable (4.39e-5)" "unprognostic (6.36e-3)" "unprognostic (3.39e-1)" "unprognostic (1.94e-1)" "unprognostic (3.74e-2)" "unprognostic (6.86e-3)" "unprognostic (4.01e-2)" "potential prognostic favorable (7.63e-4)" "unprognostic (7.49e-3)" "unprognostic (2.41e-3)" "unprognostic (2.88e-1)" "unprognostic (3.50e-1)" "unprognostic (1.47e-1)" "unprognostic (1.59e-1)" "unprognostic (4.79e-2)" "unprognostic (3.45e-2)" "unprognostic (3.16e-3)" "unprognostic (1.81e-1)" CAPN11 ENSG00000137225 "Calpain 11" Q9UMQ6 6 44158811-44184401 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "testis: 28.4" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 31.0;Early primary spermatocytes: 10.7;Early spermatids: 21.6;Late primary spermatocytes: 117.4;Late spermatids: 11.3;Platelets: 9.8" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "Leukemia: 1.0;Rhabdoid: 4.0" "Adipose visceral - Endothelial cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "CAB018070, HPA030955" Enhanced Approved "Acrosome,Equatorial segment,Mid piece,Principal piece,End piece" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 48: Non-specific - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 1 "Mid piece, Principal piece, End piece" "Acrosome, Equatorial segment" "CAB018070: , HPA030955: " "unprognostic (2.80e-1)" CAPN12 ENSG00000182472 "Calpain 12" Q6ZSI9 19 38730187-38769904 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "gallbladder: 21.3;liver: 25.9" "Cell type enriched" "Detected in some" 10 "Proximal tubule cells: 133.8" "Cell type enhanced" "Detected in many" "leukocyte: 18.8" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 13.1" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 9 "basophil: 59.4;NK-cell: 25.6" "Group enriched" "Detected in many" 9 "granulocytes: 59.4;NK-cells: 25.6" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Lung - Alveolar cells type 2, Skin - Hair cortex cells, Skin - Inner root sheath cells" "Not detected" "Not detected" "Region enhanced" "Detected in some" "hippocampal formation: 4.3" HPA053322 Approved "Nucleoplasm,Focal adhesion sites" NA NA "Cluster 32: Basophils - Transcription" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 24: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 88: Proximal tubular cells - Transmembrane transport" "Focal adhesion sites" Nucleoplasm "HPA053322: " "unprognostic (6.00e-2)" "unprognostic (1.20e-1)" "unprognostic (4.08e-2)" "unprognostic (8.10e-2)" "unprognostic (3.38e-2)" "unprognostic (3.03e-2)" "unprognostic (2.00e-3)" "unprognostic (2.76e-2)" "unprognostic (9.60e-2)" "unprognostic (4.15e-1)" "unprognostic (5.62e-2)" "potential prognostic favorable (5.96e-5)" "unprognostic (2.00e-2)" "unprognostic (2.76e-1)" "unprognostic (2.46e-1)" "potential prognostic unfavorable (7.47e-4)" "unprognostic (1.41e-1)" "unprognostic (7.04e-2)" "unprognostic (1.32e-1)" "unprognostic (2.27e-1)" "unprognostic (1.41e-1)" "unprognostic (5.84e-3)" "unprognostic (1.09e-1)" "potential prognostic unfavorable (8.16e-4)" CAPN13 FLJ23523 ENSG00000162949 "Calpain 13" Q6MZZ7 2 30722771-30820542 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 27.5;stomach 1: 26.9" "Cell type enriched" "Detected in many" 4 "Conjunctival goblet cells: 782.5" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 12.2;midbrain-derived inhibitory: 20.9;oligodendrocyte: 16.9" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 25.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 7.3" "Breast - Breast glandular cells, Colon - Colon enterocytes, Minor Salivary Gland - Minor salivary glandular cells, Skin - Sebaceous gland cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA029496, HPA029497, HPA030034" Uncertain Approved Nucleoplasm NA NA "Cluster 77: Intestine - Digestion" "Cluster 11: White matter - Signal transduction" "Cluster 27: Breast cancer - Unknown function" "Cluster 38: Secretory epithelial cells - Exocrine secretion" Nucleoplasm "HPA029496: , HPA029497: , HPA030034: " "unprognostic (2.05e-1)" "unprognostic (8.20e-2)" "unprognostic (2.36e-1)" "unprognostic (2.57e-1)" "unprognostic (1.44e-1)" "unprognostic (5.17e-2)" "unprognostic (2.34e-1)" "unprognostic (8.17e-2)" "potential prognostic favorable (4.50e-4)" "unprognostic (1.47e-2)" "unprognostic (2.91e-3)" "unprognostic (2.39e-1)" "unprognostic (1.17e-1)" "unprognostic (8.30e-2)" "unprognostic (1.84e-1)" "unprognostic (4.60e-2)" "unprognostic (2.16e-1)" "unprognostic (1.82e-1)" "unprognostic (3.63e-2)" "potential prognostic favorable (8.22e-4)" "unprognostic (9.73e-3)" "unprognostic (3.05e-1)" "unprognostic (8.48e-2)" "unprognostic (2.27e-1)" CAPN14 ENSG00000214711 "Calpain 14" A8MX76 2 31173056-31233858 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "esophagus: 175.1" "Cell type enriched" "Detected in many" 10 "Esophageal apical cells: 2577.3" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 3.5;Head and Neck Squamous Cell Carcinoma (TCGA): 3.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "cervical cancer: 1.6" "Kidney - Endothelial cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Spleen - B-cells (Spleen)" "Not detected" "Not detected" NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 7: Liver cancer - Metabolism" "Cluster 84: Apical squamous epithelium - Cornification" "unprognostic (2.18e-1)" "unprognostic (1.96e-2)" "unprognostic (2.77e-1)" "unprognostic (4.10e-2)" "unprognostic (2.93e-1)" "unprognostic (9.30e-2)" CAPN15 SOLH ENSG00000103326 "Calpain 15" O75808 16 527712-554636 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Deafness, Microphthalmia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 4.7;neutrophil: 16.5" "Lineage enriched" "Detected in many" 7 "granulocytes: 16.5" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011960, HPA074218" Approved Approved Nucleoplasm NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 54: Non-specific - Transcription" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 10 Nucleoplasm "HPA011960: , HPA074218: " "unprognostic (3.32e-2)" "unprognostic (2.07e-1)" "potential prognostic unfavorable (4.09e-4)" "unprognostic (9.29e-2)" "unprognostic (4.76e-1)" "unprognostic (3.63e-1)" "unprognostic (1.42e-2)" "unprognostic (1.58e-2)" "unprognostic (2.29e-1)" "unprognostic (1.53e-2)" "unprognostic (2.11e-2)" "unprognostic (6.24e-2)" "unprognostic (6.14e-3)" "unprognostic (1.95e-2)" "unprognostic (2.61e-1)" "potential prognostic unfavorable (9.54e-4)" "unprognostic (2.60e-1)" "unprognostic (1.86e-1)" "unprognostic (9.24e-2)" "unprognostic (1.14e-1)" "unprognostic (3.10e-1)" "unprognostic (1.02e-1)" "unprognostic (7.75e-3)" "unprognostic (4.85e-2)" "unprognostic (6.54e-2)" "unprognostic (1.06e-2)" "unprognostic (1.92e-1)" "unprognostic (2.32e-2)" "unprognostic (2.32e-1)" CAPN2 "CANPL2, CANPml, mCANP" ENSG00000162909 "Calpain 2" P17655 1 223701593-223776018 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 677.4;Esophageal apical cells: 740.8" "Cell type enhanced" "Detected in all" "astrocyte: 177.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 1, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024470 Approved Approved Supported "Cytosol,Connecting piece,Mid piece,Principal piece" NA NA 2500000 "Cluster 33: Non-specific - ATP binding" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 22 "Cytosol, Connecting piece, Mid piece" "Principal piece" "HPA024470: " "unprognostic (1.38e-1)" "unprognostic (2.67e-3)" "unprognostic (2.64e-2)" "unprognostic (1.73e-3)" "unprognostic (1.63e-1)" "unprognostic (6.13e-2)" "unprognostic (1.44e-1)" "unprognostic (4.16e-1)" "unprognostic (4.76e-2)" "unprognostic (3.20e-1)" "potential prognostic favorable (4.24e-6)" "unprognostic (3.18e-1)" "unprognostic (2.91e-1)" "unprognostic (4.07e-2)" "unprognostic (7.63e-2)" "unprognostic (5.51e-2)" "unprognostic (7.82e-3)" "unprognostic (3.16e-3)" "potential prognostic unfavorable (3.70e-4)" "unprognostic (2.03e-1)" "unprognostic (1.33e-3)" "potential prognostic unfavorable (6.98e-4)" "unprognostic (5.95e-2)" "unprognostic (7.39e-2)" "unprognostic (3.44e-1)" "unprognostic (3.48e-2)" "unprognostic (1.36e-1)" "unprognostic (8.12e-2)" "unprognostic (1.92e-1)" "unprognostic (2.11e-1)" "unprognostic (6.34e-2)" CAPN3 "CANP3, LGMD2, LGMD2A, nCL-1, p94" ENSG00000092529 "Calpain 3" P20807 15 42359498-42412949 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 318.3;skeletal muscle: 848.7;tongue: 352.2" "Cell type enriched" "Detected in some" 17 "Oligodendrocytes: 301.4" "Cell type enriched" "Detected in all" 4 "oligodendrocyte: 415.1" "Cancer enriched" "Detected in all" 7 "Skin Cutaneous Melanoma (TCGA): 294.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in many" 37 "skin cancer: 228.7" "Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040052 Enhanced NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 80: Oligodendrocytes - Myelination" 5 "HPA040052: " "unprognostic (2.29e-2)" "unprognostic (2.91e-2)" "unprognostic (3.27e-3)" "unprognostic (3.03e-2)" "unprognostic (5.19e-3)" "unprognostic (4.03e-2)" "unprognostic (2.39e-1)" "unprognostic (3.14e-1)" "unprognostic (2.61e-1)" "unprognostic (2.37e-1)" "unprognostic (3.09e-3)" "unprognostic (6.89e-3)" "unprognostic (4.03e-3)" "unprognostic (2.72e-2)" "unprognostic (2.54e-2)" "unprognostic (1.06e-3)" "unprognostic (7.54e-2)" "unprognostic (3.16e-1)" "unprognostic (2.05e-1)" "unprognostic (1.74e-1)" "unprognostic (3.60e-2)" "potential prognostic favorable (1.93e-4)" "unprognostic (4.27e-2)" "unprognostic (2.69e-1)" "unprognostic (2.92e-1)" "unprognostic (6.60e-2)" "unprognostic (2.85e-1)" "unprognostic (2.60e-3)" "unprognostic (1.15e-1)" "unprognostic (2.56e-2)" "unprognostic (1.22e-1)" CAPN5 "ADNIV, HTRA3, nCL-3, VRNI" ENSG00000149260 "Calpain 5" O15484 11 77066961-77126155 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 57.2;liver: 50.7" "Cell type enhanced" "Detected in many" "Colonocytes: 158.4;Enteric transient amplifying cells: 64.8;Enterocytes: 89.6;Esophageal apical cells: 243.7;Foveolar cells: 155.5;Goblet cells: 144.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.3" "Lineage enriched" "Detected in single" 4 "T-cells: 1.3" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Heart muscle - Fibroblasts, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary gland basal cells, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Gastric mucous cells, Testis - Sertoli cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033237, HPA072319" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 11: T-cells - Unknown function" "Cluster 17: Intestine - Digestion" "Cluster 49: Hindbrain - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 70: Intestinal goblet cells - Mucin production" 1 Nucleoplasm Cytosol "CAB033237: , HPA072319: " "unprognostic (1.27e-1)" "unprognostic (3.68e-2)" "unprognostic (1.87e-1)" "unprognostic (2.96e-2)" "unprognostic (1.35e-1)" "unprognostic (3.79e-2)" "unprognostic (1.76e-2)" "unprognostic (7.17e-2)" "unprognostic (1.19e-1)" "unprognostic (1.14e-3)" "potential prognostic favorable (2.31e-5)" "unprognostic (4.32e-2)" "unprognostic (7.31e-3)" "unprognostic (2.49e-1)" "unprognostic (8.25e-2)" "unprognostic (2.06e-2)" "unprognostic (1.11e-1)" "unprognostic (1.40e-2)" "unprognostic (1.12e-2)" "unprognostic (5.82e-2)" "unprognostic (5.42e-2)" "unprognostic (6.84e-3)" "unprognostic (7.93e-2)" "unprognostic (2.65e-1)" "unprognostic (3.50e-2)" "unprognostic (1.41e-3)" "unprognostic (5.92e-2)" "unprognostic (4.45e-2)" "unprognostic (9.08e-2)" "unprognostic (3.01e-2)" "unprognostic (1.75e-3)" CAPN6 "CalpM, CANPX, CAPNX" ENSG00000077274 "Calpain 6" Q9Y6Q1 X 111245099-111270483 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "epididymis: 200.9;placenta: 78.2;seminal vesicle: 68.2" "Cell type enhanced" "Detected in some" "Endometrial glandular cells: 29.0;Endometrial luminal cells: 60.3;Extravillous trophoblasts: 253.4;Migrating cytotrophoblasts: 190.8;Syncytiotrophoblasts: 166.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 5.7;testis cancer: 13.2" "Liver - Cholangiocytes, Minor Salivary Gland - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA040259 Uncertain "Vesicles,Centriolar satellite" NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." 1 "Vesicles, Centriolar satellite" "HPA040259: " "unprognostic (2.31e-1)" "unprognostic (1.23e-3)" "unprognostic (8.50e-3)" "unprognostic (2.43e-1)" "unprognostic (4.96e-2)" "unprognostic (4.28e-2)" "unprognostic (2.56e-1)" "unprognostic (9.55e-2)" "unprognostic (2.36e-2)" "unprognostic (2.77e-1)" "unprognostic (1.96e-2)" "unprognostic (5.36e-3)" "unprognostic (8.68e-2)" "unprognostic (1.96e-1)" "unprognostic (9.43e-2)" "unprognostic (2.77e-1)" "unprognostic (6.43e-2)" "unprognostic (1.69e-2)" "unprognostic (8.08e-2)" "unprognostic (4.49e-1)" "unprognostic (2.99e-2)" "unprognostic (1.08e-1)" "unprognostic (9.67e-2)" "unprognostic (2.01e-1)" "unprognostic (5.00e-2)" "unprognostic (5.02e-3)" "unprognostic (2.32e-1)" "unprognostic (6.43e-2)" CAPN7 PalBH ENSG00000131375 "Calpain 7" Q9Y6W3 3 15206152-15252916 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004745, HPA046617" Uncertain Approved Centrosome,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 55: Non-specific - Transcription" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 79: Photoreceptor cells - Phototransduction" 12 Cytosol Centrosome "HPA004745: , HPA046617: " "unprognostic (2.16e-1)" "unprognostic (4.76e-2)" "unprognostic (6.85e-2)" "unprognostic (1.68e-1)" "potential prognostic favorable (3.97e-4)" "unprognostic (3.03e-1)" "unprognostic (1.29e-1)" "unprognostic (3.31e-2)" "unprognostic (3.90e-3)" "unprognostic (9.36e-2)" "potential prognostic favorable (7.12e-7)" "unprognostic (1.57e-3)" "unprognostic (1.11e-1)" "unprognostic (4.26e-2)" "unprognostic (1.57e-1)" "unprognostic (3.65e-1)" "unprognostic (2.35e-1)" "unprognostic (5.16e-2)" "unprognostic (3.32e-2)" "unprognostic (8.05e-2)" "unprognostic (1.48e-2)" "unprognostic (2.29e-1)" "unprognostic (1.71e-2)" "unprognostic (7.27e-2)" "unprognostic (1.10e-2)" "unprognostic (1.20e-3)" "unprognostic (2.19e-1)" "unprognostic (1.73e-1)" "unprognostic (1.99e-1)" "unprognostic (4.93e-2)" "unprognostic (1.48e-1)" CAPN8 nCL-2 ENSG00000203697 "Calpain 8" A6NHC0 1 223538007-223665723 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "stomach 1: 274.8" "Cell type enriched" "Detected in many" 5 "Foveolar cells: 1721.3" "Cell type enhanced" "Detected in many" "amygdala excitatory: 7.9;ependymal cell: 6.6" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 47.5;Pancreatic Adenocarcinoma (TCGA): 64.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 30.1;colorectal cancer: 26.4;Gastric cancer: 30.1" "Breast - Breast glandular cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Prostate - Urothelial cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA073939 Approved "Nucleoplasm,Nuclear membrane,Vesicles" No NA "Cluster 60: Stomach - Digestion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 68: Foveolar cells - Mucosal defense" "Nucleoplasm, Nuclear membrane, Vesicles" "HPA073939: " "unprognostic (9.41e-2)" "unprognostic (4.38e-2)" "unprognostic (1.19e-1)" "unprognostic (1.76e-2)" "unprognostic (2.15e-1)" "unprognostic (2.30e-1)" "unprognostic (2.23e-2)" "unprognostic (3.47e-1)" "unprognostic (1.51e-1)" "unprognostic (1.16e-1)" "unprognostic (3.00e-3)" "unprognostic (4.68e-1)" "unprognostic (7.28e-3)" "unprognostic (1.27e-1)" "unprognostic (1.24e-2)" "unprognostic (3.22e-2)" "unprognostic (3.03e-2)" "unprognostic (1.03e-1)" "unprognostic (1.32e-1)" "unprognostic (2.38e-1)" CAPN9 "GC36, nCL-4" ENSG00000135773 "Calpain 9" O14815 1 230747384-230802003 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 20.8;stomach 1: 56.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 53.8;Cone photoreceptor cells: 91.1;Foveolar cells: 239.3;Goblet cells: 243.3;Mucous neck cells: 42.1;Respiratory ciliated cells: 37.3;Rod photoreceptor cells: 208.3" "Group enriched" "Detected in some" 4 "astrocyte: 5.1;Bergmann glia: 4.3;committed oligodendrocyte precursor: 3.7;ependymal cell: 9.1;fibroblast: 2.9;oligodendrocyte: 11.5" "Cancer enhanced" "Detected in many" "Pancreatic Adenocarcinoma (TCGA): 11.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 4.2" "Colon - Colon enterocytes, Heart muscle - Cardiomyocytes, Minor Salivary Gland - Minor salivary glandular cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA020398, CAB033483, HPA062050" Enhanced Approved "Golgi apparatus,Vesicles" NA NA "Cluster 17: Intestine - Digestion" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 70: Intestinal goblet cells - Mucin production" Vesicles "Golgi apparatus" "CAB033483: , HPA020398: , HPA062050: " "unprognostic (1.12e-2)" "unprognostic (1.05e-1)" "unprognostic (2.64e-2)" "unprognostic (1.04e-3)" "unprognostic (5.27e-2)" "unprognostic (2.40e-1)" "unprognostic (6.12e-2)" "unprognostic (5.62e-2)" "unprognostic (2.70e-1)" "unprognostic (4.52e-2)" "unprognostic (2.41e-1)" "unprognostic (4.80e-2)" "unprognostic (2.26e-2)" "unprognostic (4.13e-1)" "unprognostic (8.77e-2)" "potential prognostic unfavorable (4.47e-4)" "unprognostic (1.84e-1)" "unprognostic (1.84e-1)" CAPNS1 "30K, CANP, CANPS, CAPN4, CDPS" ENSG00000126247 "Calpain small subunit 1" P04632 19 36139953-36150353 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 705.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006872 Approved Approved Nucleoplasm,Cytosol NA NA 5800000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 1: Neurons - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 16 "Nucleoplasm, Cytosol" "HPA006872: " "unprognostic (1.36e-1)" "unprognostic (2.21e-1)" "unprognostic (5.52e-2)" "unprognostic (1.42e-1)" "unprognostic (6.39e-2)" "unprognostic (1.08e-1)" "unprognostic (1.31e-1)" "unprognostic (1.47e-2)" "unprognostic (2.15e-1)" "unprognostic (4.19e-1)" "unprognostic (6.03e-2)" "unprognostic (2.11e-2)" "potential prognostic favorable (2.92e-6)" "potential prognostic unfavorable (6.79e-5)" "unprognostic (4.83e-3)" "potential prognostic unfavorable (7.32e-6)" "unprognostic (1.18e-2)" "unprognostic (7.37e-2)" "unprognostic (6.03e-3)" "unprognostic (1.95e-1)" "unprognostic (4.28e-2)" "unprognostic (1.36e-2)" "unprognostic (1.09e-1)" "unprognostic (4.86e-2)" "unprognostic (3.35e-2)" "unprognostic (1.18e-2)" "unprognostic (3.03e-1)" "unprognostic (3.34e-2)" "unprognostic (3.93e-2)" "unprognostic (2.26e-1)" "unprognostic (6.08e-2)" CAPNS2 "MGC12536, MGC14804" ENSG00000256812 "Calpain small subunit 2" Q96L46 16 55566684-55567687 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 82.6;skin 1: 99.0;vagina: 33.3" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Bladder Urothelial Carcinoma (TCGA): 29.3;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 32.9;Head and Neck Squamous Cell Carcinoma (TCGA): 40.7;Lung Squamous Cell Carcinoma (TCGA): 30.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "eosinophil: 3.8;intermediate monocyte: 1.0" "Group enriched" "Detected in many" 9 "granulocytes: 3.8;monocytes: 1.0" "Group enriched" "Detected in some" 5 "Bladder cancer: 6.3;Esophageal cancer: 18.9;Gallbladder cancer: 6.2;Gastric cancer: 4.9;head and neck cancer: 15.3" "Prostate - Urothelial cells" "Not detected" "Not detected" "HPA059749, HPA076768" Enhanced Approved Cytosol NA NA 66000 "Cluster 19: Eosinophils - Unknown function" "Cluster 58: Skin - Keratinization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" 18 Cytosol "HPA059749: , HPA076768: " "unprognostic (9.07e-2)" "unprognostic (2.68e-1)" "unprognostic (5.12e-3)" "unprognostic (5.02e-2)" "unprognostic (9.61e-2)" "unprognostic (5.19e-2)" "unprognostic (1.09e-2)" "potential prognostic unfavorable (2.88e-4)" "unprognostic (2.32e-1)" "unprognostic (1.86e-1)" "unprognostic (4.11e-2)" CAPRIN1 "caprin-1, GPIAP1, M11S1, RNG105" ENSG00000135387 "Cell cycle associated protein 1" Q14444 11 34051731-34102610 "Predicted intracellular proteins" Differentiation "Protein synthesis inhibitor, RNA-binding" "Autism, Autism spectrum disorder, Disease variant, Intellectual disability, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 504.5;Late primary spermatocytes: 511.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018126, HPA063617" Approved Supported "Centriolar satellite,Centrosome,Cytosol" NA NA 170000 "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 24: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 203 Cytosol "Centriolar satellite, Centrosome" "HPA018126: , HPA063617: " "unprognostic (4.86e-2)" "unprognostic (8.10e-2)" "unprognostic (5.30e-2)" "unprognostic (1.69e-2)" "unprognostic (1.71e-1)" "unprognostic (1.95e-1)" "unprognostic (1.10e-1)" "unprognostic (3.75e-2)" "unprognostic (1.31e-1)" "potential prognostic unfavorable (1.70e-5)" "potential prognostic favorable (1.20e-7)" "unprognostic (3.38e-3)" "unprognostic (2.79e-1)" "unprognostic (8.14e-2)" "unprognostic (5.56e-2)" "unprognostic (1.90e-1)" "potential prognostic unfavorable (7.28e-4)" "unprognostic (3.28e-2)" "unprognostic (1.43e-1)" "unprognostic (6.66e-2)" "unprognostic (5.41e-3)" "unprognostic (1.95e-3)" "unprognostic (2.87e-1)" "unprognostic (1.58e-1)" "unprognostic (1.91e-3)" "unprognostic (8.27e-2)" "unprognostic (3.52e-2)" "unprognostic (1.04e-1)" "unprognostic (1.26e-1)" "unprognostic (5.64e-2)" "unprognostic (1.33e-1)" CAPRIN2 "C1QDC1, caprin-2, EEG1, FLJ11391, FLJ22569, RNG140" ENSG00000110888 "Caprin family member 2" Q6IMN6 12 30709552-30823302 "Predicted intracellular proteins" "Differentiation, Growth regulation" "Protein synthesis inhibitor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Bergmann glia: 122.1;Other brain neurons: 162.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039746, HPA047794" Enhanced Supported Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 72: Neuronal - Signal transduction" "Cluster 109: Neurons - Neuronal signaling" 4 Cytosol "Nucleoplasm, Centrosome" "HPA039746: , HPA047794: " "unprognostic (2.31e-3)" "unprognostic (2.87e-1)" "unprognostic (1.39e-1)" "unprognostic (4.18e-2)" "unprognostic (1.12e-3)" "unprognostic (6.94e-2)" "unprognostic (3.20e-2)" "unprognostic (1.01e-1)" "unprognostic (1.40e-1)" "unprognostic (7.94e-2)" "potential prognostic unfavorable (2.38e-4)" "unprognostic (1.03e-2)" "unprognostic (6.00e-3)" "unprognostic (2.42e-1)" "unprognostic (2.37e-1)" "unprognostic (1.34e-1)" "unprognostic (3.59e-1)" "unprognostic (4.29e-2)" "unprognostic (2.28e-1)" "unprognostic (1.16e-1)" "unprognostic (3.48e-2)" "unprognostic (2.18e-1)" "potential prognostic unfavorable (1.11e-5)" "unprognostic (6.91e-2)" "unprognostic (4.24e-1)" "unprognostic (3.62e-2)" "unprognostic (1.11e-1)" "unprognostic (7.32e-2)" "unprognostic (1.33e-1)" "unprognostic (9.67e-2)" "unprognostic (8.75e-2)" CAPS "CAPS1, MGC126562" ENSG00000105519 Calcyphosine Q13938 19 5912339-5916211 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "fallopian tube: 314.9" "Group enriched" "Detected in many" 4 "Endometrial ciliated cells: 2807.6;Epididymal efferent duct ciliated cells: 3324.5;Fallopian tube ciliated cells: 4685.1;Respiratory ciliated cells: 3276.4" "Cell type enriched" "Detected in all" 23 "ependymal cell: 990.8" "Cancer enriched" "Detected in all" 5 "Uterine Corpus Endometrial Carcinoma (TCGA): 685.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "breast cancer: 76.6" "Colon - Enteric glia cells, Lung - Respiratory ciliated cells" "Low region specificity" "Detected in all" HPA043520 Enhanced Supported "Plasma membrane,Cytosol" NA NA 27000 "Cluster 33: Non-specific - ATP binding" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 107: Ciliated cells - Cilia assembly & function" 1 Cytosol "Plasma membrane" "HPA043520: " "unprognostic (7.18e-3)" "unprognostic (2.13e-1)" "unprognostic (3.36e-1)" "unprognostic (1.30e-1)" "unprognostic (2.91e-2)" "unprognostic (2.52e-1)" "unprognostic (9.61e-2)" "unprognostic (4.38e-2)" "unprognostic (3.52e-3)" "unprognostic (1.33e-1)" "potential prognostic unfavorable (1.41e-6)" "unprognostic (2.66e-2)" "unprognostic (3.92e-2)" "unprognostic (1.31e-1)" "unprognostic (1.57e-2)" "unprognostic (1.05e-3)" "unprognostic (9.57e-2)" "unprognostic (1.50e-1)" "unprognostic (3.32e-1)" "unprognostic (1.85e-1)" "unprognostic (1.90e-1)" "unprognostic (1.89e-1)" "unprognostic (3.28e-2)" "unprognostic (1.38e-1)" "unprognostic (7.09e-2)" "unprognostic (6.13e-3)" "unprognostic (2.06e-1)" "unprognostic (1.21e-1)" "unprognostic (1.19e-1)" "unprognostic (3.92e-2)" "unprognostic (3.54e-2)" CAPS2 ENSG00000180881 "Calcyphosine 2" Q9BXY5 12 75275979-75390928 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 9.4" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 257.0;Ependymal cells: 351.0;Gonadotrophs: 250.8;Lactotrophs: 264.8;Respiratory ciliated cells: 207.7" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Kidney Chromophobe (TCGA): 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA039542, HPA040004" Uncertain Approved Nucleoplasm,Nucleoli,Vesicles,Centrosome Yes No "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 5: Rhabdoid - Unknown function" "Cluster 109: Neurons - Neuronal signaling" Nucleoli "Nucleoplasm, Vesicles, Centrosome" "HPA039542: , HPA040004: " "unprognostic (1.05e-1)" "unprognostic (1.10e-1)" "unprognostic (1.63e-2)" "unprognostic (4.87e-2)" "unprognostic (2.40e-2)" "unprognostic (1.70e-2)" "unprognostic (7.26e-2)" "unprognostic (1.61e-1)" "unprognostic (1.35e-1)" "unprognostic (2.04e-2)" "unprognostic (2.15e-1)" "unprognostic (4.45e-2)" CAPSL MGC26610 ENSG00000152611 "Calcyphosine like" Q8WWF8 5 35904288-35938779 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "choroid plexus: 86.0;fallopian tube: 104.2" "Cell type enhanced" "Detected in some" "Early spermatids: 149.7;Endometrial ciliated cells: 409.4;Ependymal cells: 148.5;Epididymal efferent duct ciliated cells: 536.4;Fallopian tube ciliated cells: 852.2;Late primary spermatocytes: 121.1;Late spermatids: 207.7;Respiratory ciliated cells: 771.5" "Group enriched" "Detected in some" 9 "choroid plexus epithelial cell: 60.5;ependymal cell: 199.3" "Cancer enriched" "Detected in many" 5 "Uterine Corpus Endometrial Carcinoma (TCGA): 27.9" "Region enhanced" "Detected in all" "choroid plexus: 52.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Adrenocortical cancer: 2.9;Leukemia: 2.2" "Lung - Respiratory ciliated cells, Skin - Inner root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA046811, HPA058495" Enhanced Approved "Nucleoplasm,Plasma membrane,Microtubules,Cytokinetic bridge,Primary cilium" Yes No "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 35: RS4;11 - Unknown function" "Cluster 107: Ciliated cells - Cilia assembly & function" 2 "Nucleoplasm, Microtubules, Primary cilium" "Plasma membrane, Cytokinetic bridge" "HPA046811: , HPA058495: " "unprognostic (4.75e-2)" "unprognostic (2.34e-2)" "unprognostic (1.03e-1)" "unprognostic (2.81e-2)" "unprognostic (3.40e-3)" "unprognostic (1.94e-1)" "unprognostic (6.44e-2)" "unprognostic (3.66e-1)" "unprognostic (3.20e-1)" "unprognostic (5.03e-2)" "unprognostic (2.36e-2)" "unprognostic (8.26e-2)" "unprognostic (5.49e-3)" "unprognostic (1.72e-1)" "unprognostic (9.69e-3)" "unprognostic (2.27e-1)" CAPZA1 ENSG00000116489 "Capping actin protein of muscle Z-line subunit alpha 1" P52907 1 112619805-112671616 "Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 741.3;Kupffer cells: 618.0;Neutrophil progenitors: 709.1;Neutrophils: 1339.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB045963 Approved NA NA 12000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 37: Non-specific - mRNA processing" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 80 "CAB045963: " "unprognostic (1.63e-1)" "unprognostic (2.63e-2)" "unprognostic (7.55e-2)" "unprognostic (3.09e-1)" "potential prognostic favorable (1.71e-4)" "unprognostic (3.39e-2)" "unprognostic (1.07e-1)" "unprognostic (2.53e-1)" "unprognostic (9.14e-2)" "unprognostic (1.69e-2)" "potential prognostic unfavorable (5.25e-5)" "unprognostic (1.26e-1)" "unprognostic (8.58e-3)" "potential prognostic unfavorable (8.71e-6)" "unprognostic (1.68e-3)" "validated prognostic unfavorable (1.20e-4)" "validated prognostic unfavorable (9.36e-4)" "unprognostic (2.02e-1)" "unprognostic (1.20e-1)" "unprognostic (5.49e-2)" "unprognostic (2.84e-2)" "unprognostic (4.35e-3)" "unprognostic (2.19e-3)" "unprognostic (2.03e-1)" "unprognostic (2.49e-2)" "unprognostic (3.04e-1)" "unprognostic (4.74e-3)" "unprognostic (3.49e-2)" "unprognostic (2.35e-1)" "unprognostic (1.28e-1)" "unprognostic (2.95e-2)" CAPZA2 "CAPPA2, CAPZ" ENSG00000198898 "Capping actin protein of muscle Z-line subunit alpha 2" P47755 7 116811070-116922049 "Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial glandular cells: 770.6;Neutrophils: 960.4;Platelets: 872.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Smooth muscle cells, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007470, HPA007643" Uncertain Approved Cytosol No No 5700000 "Cluster 28: Neutrophils - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 35: Non-specific - DNA binding" "Cluster 61: BICR 18 - Protein kinases" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 128 Cytosol "HPA007470: , HPA007643: " "unprognostic (5.24e-2)" "unprognostic (1.48e-1)" "unprognostic (8.72e-3)" "potential prognostic unfavorable (7.17e-4)" "unprognostic (2.21e-1)" "unprognostic (1.50e-3)" "unprognostic (1.09e-2)" "unprognostic (2.31e-2)" "unprognostic (4.35e-2)" "potential prognostic unfavorable (3.00e-4)" "unprognostic (5.37e-3)" "unprognostic (4.96e-2)" "unprognostic (1.10e-2)" "potential prognostic unfavorable (5.72e-5)" "unprognostic (1.56e-3)" "unprognostic (1.16e-1)" "unprognostic (7.98e-2)" "unprognostic (4.84e-2)" "unprognostic (1.46e-1)" "unprognostic (4.09e-2)" "potential prognostic unfavorable (1.73e-4)" "unprognostic (1.12e-2)" "unprognostic (1.08e-2)" "unprognostic (4.07e-1)" "unprognostic (2.54e-1)" "unprognostic (5.41e-2)" "unprognostic (3.95e-2)" "unprognostic (9.68e-3)" "unprognostic (1.09e-1)" "unprognostic (1.55e-2)" "unprognostic (4.45e-2)" CAPZA3 "CAPPA3, Gsg3" ENSG00000177938 "Capping actin protein of muscle Z-line subunit alpha 3" Q96KX2 12 18738119-18739188 "Predicted intracellular proteins" "Actin capping, Actin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 86 "testis: 175.7" "Group enriched" "Detected in some" 10 "Early spermatids: 2841.2;Late spermatids: 10438.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA038688 Enhanced Approved Calyx NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 5: Rhabdoid - Unknown function" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" Calyx "HPA038688: " "unprognostic (2.57e-1)" CAPZB ENSG00000077549 "Capping actin protein of muscle Z-line subunit beta" P47756 1 19338775-19485539 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 1378.0;Esophageal apical cells: 1195.9;Hofbauer cells: 1600.0;Late spermatids: 6076.1" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 696.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031531 Approved Approved Nucleoplasm,Vesicles,Cytosol No No 8500000 "Cluster 25: Non-specific - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 27: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 905 "Nucleoplasm, Cytosol" Vesicles "HPA031531: " "unprognostic (7.13e-2)" "unprognostic (3.37e-1)" "unprognostic (2.42e-2)" "unprognostic (6.29e-2)" "unprognostic (1.97e-1)" "unprognostic (6.07e-2)" "unprognostic (1.00e-2)" "unprognostic (1.86e-2)" "unprognostic (1.08e-1)" "unprognostic (2.15e-2)" "unprognostic (3.68e-3)" "unprognostic (5.48e-2)" "unprognostic (6.65e-3)" "validated prognostic unfavorable (4.39e-5)" "validated prognostic unfavorable (6.46e-5)" "validated prognostic unfavorable (8.03e-4)" "validated prognostic unfavorable (4.17e-4)" "unprognostic (4.26e-2)" "unprognostic (1.66e-2)" "unprognostic (1.17e-2)" "unprognostic (2.03e-1)" "unprognostic (8.64e-3)" "unprognostic (2.49e-1)" "unprognostic (3.07e-1)" "unprognostic (1.12e-2)" "unprognostic (3.64e-2)" "unprognostic (1.34e-1)" "unprognostic (1.19e-1)" "unprognostic (2.23e-1)" "unprognostic (1.30e-1)" "unprognostic (8.85e-2)" CARD10 "BIMP1, CARMA3" ENSG00000100065 "Caspase recruitment domain family member 10" Q9BWT7 22 37490362-37519542 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 33.8" "Cell type enhanced" "Detected in many" "Colonocytes: 25.8;Enterocytes: 41.9;Goblet cells: 35.1;Lymphatic endothelial cells: 49.4;Pancreatic duct cells: 29.5;Paneth cells: 27.1;Proximal tubule cells: 23.5;Sertoli cells: 45.2;Tuft cells: 34.6;Vascular endothelial cells: 29.4" "Cell type enriched" "Detected in some" 4 "endothelial cell: 30.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Testis - Sertoli cells, Thyroid gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA029359, HPA074912" Approved Approved Cytosol NA No "Cluster 77: Intestine - Digestion" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 94 Cytosol "HPA029359: , HPA074912: " "unprognostic (1.70e-1)" "unprognostic (1.21e-1)" "unprognostic (6.20e-2)" "unprognostic (6.99e-2)" "unprognostic (1.73e-1)" "unprognostic (5.47e-2)" "unprognostic (1.14e-1)" "unprognostic (2.74e-1)" "unprognostic (2.81e-2)" "unprognostic (4.53e-3)" "potential prognostic favorable (3.84e-6)" "unprognostic (3.37e-3)" "unprognostic (1.27e-2)" "potential prognostic unfavorable (1.32e-4)" "unprognostic (6.76e-3)" "unprognostic (9.84e-2)" "unprognostic (8.92e-2)" "unprognostic (8.83e-3)" "unprognostic (3.10e-1)" "unprognostic (1.89e-1)" "unprognostic (3.21e-1)" "unprognostic (1.33e-2)" "unprognostic (1.61e-1)" "unprognostic (2.18e-2)" "unprognostic (1.64e-2)" "unprognostic (2.49e-1)" "unprognostic (6.96e-2)" "unprognostic (2.45e-2)" "unprognostic (1.57e-1)" "unprognostic (1.86e-1)" "unprognostic (2.82e-2)" CARD11 "BIMP3, CARMA1" ENSG00000198286 "Caspase recruitment domain family member 11" Q9BXL7 7 2906142-3044228 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" Immunity "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 17.3;lymphoid tissue: 37.8" "Cell type enhanced" "Detected in many" "B-cells: 429.6;Innate lymphoid cells: 203.5;Microglia: 205.8;NK-cells: 601.4;Papillary tip epithelial cells: 153.6;pDCs: 503.7;T-cells: 303.4;Thymocytes: 194.8;Urothelial cells: 341.7" "Group enriched" "Detected in many" 6 "central nervous system macrophage: 272.0;leukocyte: 498.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 20.8" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "lymphoma: 62.6;pancreatic cancer: 43.3" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Prostate - T-cells, Skin - T-cells, Spleen - B-cells (Spleen), Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA052984 Approved NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 38: Sub-cortical - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 20 "HPA052984: " "unprognostic (2.29e-2)" "unprognostic (5.99e-2)" "unprognostic (4.50e-3)" "unprognostic (1.60e-1)" "unprognostic (1.13e-2)" "unprognostic (7.96e-2)" "unprognostic (2.02e-1)" "unprognostic (2.90e-1)" "unprognostic (4.36e-2)" "unprognostic (9.17e-3)" "potential prognostic unfavorable (8.76e-4)" "unprognostic (3.91e-2)" "unprognostic (8.00e-2)" "unprognostic (1.64e-1)" "unprognostic (1.61e-2)" "unprognostic (2.33e-2)" "unprognostic (4.05e-2)" "unprognostic (7.11e-2)" "unprognostic (6.71e-2)" "unprognostic (2.52e-2)" "unprognostic (1.42e-1)" "unprognostic (4.01e-2)" "unprognostic (1.45e-2)" "unprognostic (1.83e-1)" "unprognostic (5.94e-2)" "unprognostic (1.12e-2)" "unprognostic (7.97e-2)" "unprognostic (3.23e-2)" "unprognostic (7.05e-2)" "unprognostic (9.71e-2)" "unprognostic (1.75e-2)" CARD14 "BIMP2, CARMA2, PSORS2" ENSG00000141527 "Caspase recruitment domain family member 14" Q9BXL6 17 80169992-80216073 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Apoptosis "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 9.0;skin 1: 9.9;vagina: 4.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 30.1;Epicardial cells: 34.1;Esophageal apical cells: 91.6;Esophageal suprabasal cells: 48.9;Kupffer cells: 31.8;Suprabasal keratinocytes: 27.9" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 11.6;oligodendrocyte: 14.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Prostate - Prostate basal glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA023388 Supported Cytosol NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 6: Non-specific - Immune response" "Cluster 7: Liver cancer - Metabolism" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 4 Cytosol "HPA023388: " "unprognostic (2.19e-1)" "unprognostic (3.05e-3)" "unprognostic (8.20e-2)" "unprognostic (1.60e-2)" "unprognostic (8.85e-2)" "unprognostic (1.32e-1)" "unprognostic (9.76e-2)" "unprognostic (4.76e-2)" "unprognostic (2.05e-2)" "unprognostic (8.34e-3)" "unprognostic (5.42e-2)" "unprognostic (8.07e-2)" "unprognostic (9.64e-2)" "unprognostic (1.41e-3)" "unprognostic (1.44e-1)" "unprognostic (4.28e-3)" "unprognostic (5.97e-2)" "unprognostic (1.78e-2)" "unprognostic (9.73e-2)" "unprognostic (1.80e-1)" "unprognostic (3.87e-2)" CARD16 "COP, COP1, LLID-114769, PSEUDO-ICE" ENSG00000204397 "Caspase recruitment domain family member 16" Q5EG05 11 105041326-105101431 "Predicted intracellular proteins" "Protease inhibitor, Thiol protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "cDC: 206.7;Enterocytes: 95.7;Hepatic stellate cells: 103.3;Kupffer cells: 182.4;Macrophages: 90.0;monocytes: 187.2;Neutrophils: 322.9;Platelets: 133.7" "Group enriched" "Detected in some" 4 "endothelial cell: 15.1;leukocyte: 23.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Rhabdoid: 70.6" "Breast - T-cells" "HPA053981, HPA062805" Uncertain Approved Mitochondria NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 1 Mitochondria "HPA053981: , HPA062805: " CARD18 "ICEBERG, pseudo-ICE, UNQ5804" ENSG00000255501 "Caspase recruitment domain family member 18" P57730 11 105137714-105531697 "Predicted intracellular proteins" "Protease inhibitor, Thiol protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "skin 1: 40.1" "Cell type enhanced" "Detected in many" "Bergmann glia: 96.0;Cytotrophoblasts: 141.8;Differentiating spermatogonia: 63.6;Early primary spermatocytes: 114.9;Early spermatids: 63.3;Extravillous trophoblasts: 86.3;Gastric progenitor cells: 107.7;Hofbauer cells: 78.9;Late primary spermatocytes: 66.5;Migrating cytotrophoblasts: 73.4;Müller glia: 113.5;Syncytiotrophoblasts: 72.6" "Cell type enhanced" "Detected in many" "Bergmann glia: 97.7;cerebellar inhibitory: 45.6" "Cancer enhanced" "Detected in some" "Head and Neck Squamous Cell Carcinoma (TCGA): 8.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 4.7" "Skin - Sebaceous gland cells, Testis - Early spermatids, Testis - Late spermatids" HPA038582 Approved NA NA "Cluster 37: Skin - Keratinization" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 1 "HPA038582: " "unprognostic (3.04e-1)" "unprognostic (3.93e-2)" "unprognostic (1.86e-1)" "unprognostic (3.11e-2)" "unprognostic (4.71e-2)" "unprognostic (4.81e-1)" "unprognostic (8.82e-2)" CARD19 "bA370F5.1, BinCARD, C9orf89, MGC11115" ENSG00000165233 "Caspase recruitment domain family member 19" Q96LW7 9 93096217-93113283 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 173.4;Megakaryocytes: 315.3;Platelets: 1064.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipose progenitor cells, Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010921, HPA010990, HPA038297" Approved Supported Mitochondria NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 45: Non-specific - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 47: Platelets - Hemostasis" 3 Mitochondria "HPA010921: , HPA010990: , HPA038297: " "unprognostic (2.84e-3)" "unprognostic (2.72e-1)" "unprognostic (2.08e-1)" "unprognostic (2.86e-2)" "unprognostic (2.12e-1)" "unprognostic (1.17e-3)" "potential prognostic unfavorable (2.91e-4)" "unprognostic (2.03e-2)" "unprognostic (2.80e-1)" "unprognostic (1.35e-1)" "unprognostic (6.29e-3)" "unprognostic (4.66e-2)" "unprognostic (1.94e-3)" "unprognostic (1.34e-2)" "unprognostic (7.42e-3)" "unprognostic (2.16e-2)" "unprognostic (1.69e-1)" "unprognostic (1.18e-2)" "unprognostic (3.28e-1)" "unprognostic (4.02e-2)" "unprognostic (7.05e-2)" "unprognostic (4.62e-1)" "unprognostic (7.03e-2)" "unprognostic (3.48e-1)" "unprognostic (2.75e-3)" "unprognostic (1.27e-2)" "unprognostic (4.01e-2)" "unprognostic (8.79e-2)" "unprognostic (6.73e-2)" CARD6 CINCIN1 ENSG00000132357 "Caspase recruitment domain family member 6" Q9BX69 5 40841308-40860175 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 51.6;Esophageal suprabasal cells: 34.4;Kupffer cells: 32.8;Lymphatic endothelial cells: 44.6;Neutrophil progenitors: 35.4;Neutrophils: 89.2" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 17.0;endothelial cell: 27.0;fibroblast: 16.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 27.4" "Group enriched" "Detected in all" 5 "dendritic cells: 7.7;granulocytes: 27.4;monocytes: 13.9" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Pituitary gland - Endothelial cells" "Low region specificity" "Detected in many" HPA041933 Approved NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 48: Neutrophils - Phagocytosis & degranulation" "HPA041933: " "unprognostic (1.27e-1)" "unprognostic (6.31e-2)" "unprognostic (2.47e-1)" "unprognostic (1.75e-2)" "unprognostic (2.74e-3)" "unprognostic (1.60e-1)" "unprognostic (8.76e-2)" "unprognostic (2.01e-3)" "unprognostic (1.73e-1)" "unprognostic (4.94e-2)" "potential prognostic favorable (5.46e-4)" "unprognostic (2.80e-2)" "unprognostic (1.99e-1)" "unprognostic (2.53e-3)" "unprognostic (1.11e-1)" "unprognostic (4.04e-1)" "unprognostic (4.61e-2)" "unprognostic (1.82e-2)" "unprognostic (2.49e-2)" "unprognostic (7.82e-2)" "unprognostic (3.35e-2)" "unprognostic (1.46e-2)" "unprognostic (3.16e-2)" "unprognostic (2.62e-1)" "unprognostic (5.02e-2)" "unprognostic (1.61e-1)" "unprognostic (1.35e-2)" "unprognostic (7.93e-2)" "unprognostic (8.18e-2)" "unprognostic (8.51e-2)" "unprognostic (3.40e-2)" CARD8 "CARDINAL, Dakar, KIAA0955, NDPP, TUCAN" ENSG00000105483 "Caspase recruitment domain family member 8" Q9Y2G2 19 48180770-48255946 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction, Immunity, Inflammatory response, Innate immunity, Necrosis" "Hydrolase, Protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglia: 149.2;Neutrophil progenitors: 157.4;Neutrophils: 385.4;Platelets: 132.4;Vascular endothelial cells: 135.9" "Group enriched" "Detected in all" 4 "central nervous system macrophage: 195.4;endothelial cell: 164.3;leukocyte: 155.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA042071, HPA043513" Supported Supported Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 1 Nucleoplasm "HPA042071: , HPA043513: " "unprognostic (4.14e-2)" "unprognostic (1.74e-1)" "unprognostic (9.40e-2)" "unprognostic (6.09e-2)" "unprognostic (6.91e-2)" "unprognostic (1.13e-1)" "unprognostic (2.37e-1)" "unprognostic (1.65e-1)" "unprognostic (1.66e-1)" "unprognostic (3.06e-1)" "unprognostic (2.47e-3)" "unprognostic (1.28e-2)" "unprognostic (6.70e-2)" "unprognostic (4.97e-2)" "unprognostic (8.07e-2)" "unprognostic (7.64e-2)" "unprognostic (1.49e-1)" "unprognostic (2.09e-1)" "unprognostic (9.86e-2)" "unprognostic (1.58e-1)" "unprognostic (3.05e-1)" "unprognostic (1.20e-1)" "unprognostic (5.56e-2)" "unprognostic (6.78e-2)" "unprognostic (1.93e-1)" "unprognostic (7.39e-2)" "unprognostic (8.84e-3)" "unprognostic (4.57e-2)" "unprognostic (1.58e-1)" "unprognostic (2.97e-1)" "unprognostic (1.75e-1)" CARD9 ENSG00000187796 "Caspase recruitment domain family member 9" Q9H257 9 136363956-136373681 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.8;lymphoid tissue: 8.1" "Cell type enriched" "Detected in some" 4 "Microglia: 22.7" "Cell type enriched" "Detected in many" 8 "central nervous system macrophage: 27.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 56.3;non-classical monocyte: 48.7" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in some" 6 "Leukemia: 13.1" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Heart muscle - Macrophages, Prostate - T-cells, Skeletal muscle - Macrophages, Skin - Langerhans cells, Stomach - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA059502 Enhanced NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 63 "HPA059502: " "unprognostic (5.64e-2)" "unprognostic (9.93e-2)" "unprognostic (6.36e-3)" "unprognostic (6.58e-3)" "unprognostic (1.78e-1)" "unprognostic (1.56e-1)" "unprognostic (3.99e-2)" "unprognostic (4.70e-2)" "unprognostic (7.05e-2)" "unprognostic (1.01e-1)" "unprognostic (4.61e-2)" "unprognostic (2.45e-3)" "unprognostic (8.26e-2)" "unprognostic (1.78e-2)" "unprognostic (1.92e-1)" "unprognostic (1.06e-1)" "unprognostic (2.52e-3)" "unprognostic (7.63e-2)" "unprognostic (8.44e-3)" "unprognostic (1.14e-1)" CARF "ALS2CR8, FLJ21579, NYD-SP24" ENSG00000138380 "Calcium responsive transcription factor" Q8N187 2 202912214-202988263 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Myonuclei: 109.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034557, HPA043191" Approved Approved "Nucleoli fibrillar center,Vesicles,Cytosol" NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 7: Non-specific - Transcription" 5 Vesicles "Nucleoli fibrillar center, Cytosol" "HPA034557: , HPA043191: " "unprognostic (9.71e-2)" "unprognostic (3.64e-1)" "unprognostic (5.52e-3)" "unprognostic (5.66e-2)" "unprognostic (2.71e-2)" "unprognostic (1.73e-1)" "unprognostic (1.28e-1)" "unprognostic (2.83e-3)" "unprognostic (4.02e-1)" "unprognostic (4.10e-3)" "unprognostic (1.44e-3)" "potential prognostic favorable (9.77e-4)" "unprognostic (1.77e-1)" "unprognostic (3.10e-2)" "unprognostic (8.50e-2)" "unprognostic (5.48e-2)" "unprognostic (7.64e-2)" "unprognostic (2.99e-1)" "unprognostic (8.36e-2)" "unprognostic (8.66e-2)" "unprognostic (5.40e-3)" "unprognostic (2.03e-1)" "unprognostic (1.24e-2)" "unprognostic (2.02e-2)" "unprognostic (6.29e-2)" "unprognostic (2.25e-1)" "unprognostic (1.37e-1)" "unprognostic (3.36e-2)" "unprognostic (3.53e-1)" CARHSP1 "CRHSP-24, CSDC1" ENSG00000153048 "Calcium regulated heat stable protein 1" Q9Y2V2 16 8852942-8869012 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 403.7" "Cell type enhanced" "Detected in all" "Early spermatids: 2192.7;Esophageal apical cells: 4461.7;Late primary spermatocytes: 878.5;Late spermatids: 12214.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051911 Enhanced NA Yes 150000 "Cluster 28: Neutrophils - Unknown function" "Cluster 67: Testis - Mixed function" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 13 "HPA051911: " "unprognostic (6.02e-2)" "unprognostic (4.42e-2)" "unprognostic (6.74e-2)" "unprognostic (1.11e-1)" "unprognostic (1.54e-1)" "unprognostic (1.99e-1)" "unprognostic (1.70e-2)" "unprognostic (3.38e-1)" "unprognostic (1.82e-2)" "unprognostic (6.50e-3)" "unprognostic (1.01e-3)" "unprognostic (3.60e-2)" "unprognostic (1.45e-1)" "unprognostic (7.55e-3)" "unprognostic (1.82e-2)" "validated prognostic unfavorable (8.73e-5)" "validated prognostic unfavorable (1.25e-4)" "unprognostic (8.37e-2)" "unprognostic (3.01e-1)" "unprognostic (7.39e-3)" "unprognostic (2.37e-1)" "unprognostic (2.01e-3)" "unprognostic (1.03e-2)" "unprognostic (6.22e-2)" "unprognostic (1.38e-1)" "unprognostic (1.74e-1)" "unprognostic (1.70e-1)" "unprognostic (1.56e-1)" "unprognostic (3.57e-2)" "unprognostic (7.75e-2)" "unprognostic (1.04e-1)" CARM1 PRMT4 ENSG00000142453 "Coactivator associated arginine methyltransferase 1" Q86X55 19 10871553-10923075 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 103.6" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032961, HPA043561, HPA048073, HPA069313" Supported Enhanced Nucleoplasm NA NA 29000 "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 51: Neurons - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 63 Nucleoplasm "CAB032961: , HPA043561: , HPA048073: , HPA069313: " "unprognostic (1.34e-1)" "unprognostic (3.74e-2)" "unprognostic (9.16e-3)" "unprognostic (3.09e-1)" "unprognostic (6.22e-2)" "unprognostic (1.26e-1)" "unprognostic (2.05e-2)" "unprognostic (1.95e-1)" "unprognostic (1.44e-1)" "unprognostic (3.74e-1)" "unprognostic (1.92e-2)" "unprognostic (1.34e-1)" "unprognostic (1.30e-2)" "unprognostic (4.35e-3)" "unprognostic (8.28e-3)" "unprognostic (5.99e-3)" "potential prognostic unfavorable (4.70e-4)" "unprognostic (1.83e-1)" "unprognostic (6.40e-2)" "unprognostic (1.01e-1)" "unprognostic (1.42e-1)" "unprognostic (7.28e-2)" "unprognostic (2.41e-1)" "unprognostic (8.58e-2)" "unprognostic (2.75e-2)" "unprognostic (1.26e-1)" "unprognostic (1.19e-1)" "unprognostic (5.73e-2)" "unprognostic (4.11e-2)" "unprognostic (1.90e-1)" "unprognostic (8.71e-2)" CARMIL1 "CARMIL, dJ501N12.1, FLJ20048, LRRC16, LRRC16A" ENSG00000079691 "Capping protein regulator and myosin 1 linker 1" Q5VZK9 6 25279078-25620530 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 948.4;Bergmann glia: 1307.7;Sertoli cells: 1755.7;Tuft cells: 645.6" "Cell type enhanced" "Detected in all" "astrocyte: 914.3;Bergmann glia: 1405.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029038, HPA029039" Enhanced Supported "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 7 "Plasma membrane, Cytosol" "Nuclear speckles" "HPA029038: , HPA029039: " "unprognostic (1.71e-1)" "unprognostic (1.09e-2)" "unprognostic (2.44e-1)" "unprognostic (2.07e-2)" "unprognostic (2.47e-2)" "unprognostic (2.31e-1)" "unprognostic (1.79e-3)" "unprognostic (1.08e-1)" "unprognostic (3.39e-3)" "potential prognostic favorable (2.03e-6)" "unprognostic (6.39e-2)" "unprognostic (3.56e-1)" "unprognostic (6.99e-3)" "unprognostic (2.03e-1)" "unprognostic (4.20e-1)" "unprognostic (2.41e-1)" "unprognostic (9.50e-2)" "unprognostic (1.17e-1)" "unprognostic (2.50e-1)" "unprognostic (3.48e-3)" "unprognostic (2.28e-2)" "unprognostic (2.17e-1)" "unprognostic (2.68e-2)" "unprognostic (2.82e-2)" "unprognostic (8.78e-2)" "unprognostic (1.20e-1)" "unprognostic (2.64e-1)" "unprognostic (2.54e-3)" "unprognostic (2.70e-2)" CARMIL2 "LRRC16C, RLTPR" ENSG00000159753 "Capping protein regulator and myosin 1 linker 2" Q6F5E8 16 67644988-67657569 "Disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 15.2;intestine: 12.7;lymphoid tissue: 22.3" "Cell type enhanced" "Detected in some" "B-cells: 11.0;Brain excitatory neurons: 27.0;Brain inhibitory neurons: 20.6;Hematopoietic stem cells: 8.7;Lactotrophs: 8.3;Other brain neurons: 21.2;Pancreatic islet cells: 8.2;pDCs: 8.8;Retinal amacrine cells: 9.4;Retinal horizontal cells: 22.0;Somatotrophs: 11.5;T-cells: 10.3;Thymocytes: 8.5" "Cell type enhanced" "Detected in all" "hippocampal CA4: 73.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Leukemia: 28.3;lymphoma: 35.9" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Liver - T-cells, Prostate - T-cells, Skin - T-cells, Spleen - B-cells (Spleen), Stomach - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA041402 Approved NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 35: Neurons - Synaptic function & neurogenesis" 7 "HPA041402: " "unprognostic (9.76e-3)" "unprognostic (8.56e-3)" "potential prognostic favorable (3.45e-4)" "unprognostic (3.46e-3)" "unprognostic (7.94e-2)" "unprognostic (4.49e-2)" "unprognostic (6.18e-2)" "unprognostic (3.58e-1)" "unprognostic (1.42e-2)" "unprognostic (3.03e-1)" "unprognostic (3.00e-1)" "potential prognostic favorable (1.90e-4)" "potential prognostic favorable (1.60e-4)" "unprognostic (2.92e-3)" "unprognostic (2.48e-1)" "unprognostic (1.08e-1)" CARMIL3 "BC008134, C14orf121, crml-1, LRRC16B" ENSG00000186648 "Capping protein regulator and myosin 1 linker 3" Q8ND23 14 24052009-24069729 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 22.1;pituitary gland: 7.7" "Group enriched" "Detected in some" 5 "Astrocytes: 9.4;Bergmann glia: 4.7;Brain excitatory neurons: 12.1;Brain inhibitory neurons: 14.2;Oligodendrocyte progenitor cells: 7.1;Other brain neurons: 11.9" "Cell type enhanced" "Detected in many" "midbrain-derived inhibitory: 43.9" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 3.4" "Adrenal gland - Adrenal medulla cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030596 Uncertain NA NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" "HPA030596: " "unprognostic (2.33e-2)" "potential prognostic favorable (2.01e-4)" "unprognostic (1.21e-1)" CARNMT1 "C9orf41, FLJ25795" ENSG00000156017 "Carnosine N-methyltransferase 1" Q8N4J0 9 74980790-75028423 "Enzymes, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 348.1;Late primary spermatocytes: 213.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026756 Uncertain NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 76: Non-specific - Metabolism" "Cluster 15: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 23 "HPA026756: " "unprognostic (5.76e-3)" "unprognostic (1.31e-1)" "unprognostic (2.40e-2)" "unprognostic (1.26e-1)" "unprognostic (1.42e-1)" "unprognostic (8.85e-2)" "unprognostic (1.59e-1)" "unprognostic (3.87e-1)" "unprognostic (6.53e-2)" "potential prognostic favorable (1.62e-5)" "unprognostic (1.60e-3)" "unprognostic (1.03e-1)" "unprognostic (2.90e-2)" "unprognostic (1.19e-2)" "unprognostic (7.10e-2)" "unprognostic (1.76e-1)" "unprognostic (3.37e-1)" "unprognostic (3.46e-2)" "unprognostic (2.54e-2)" "unprognostic (1.49e-2)" "unprognostic (8.69e-2)" "unprognostic (8.70e-2)" "unprognostic (4.65e-2)" "unprognostic (1.56e-1)" "unprognostic (4.56e-1)" "unprognostic (1.61e-1)" "unprognostic (4.89e-1)" "unprognostic (2.40e-1)" "unprognostic (3.52e-1)" CARNS1 "ATPGD1, KIAA1394" ENSG00000172508 "Carnosine synthase 1" A5YM72 11 67414968-67425607 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 165.8;skeletal muscle: 70.1" "Cell type enriched" "Detected in some" 8 "Oligodendrocytes: 418.2" "Group enriched" "Detected in many" 16 "committed oligodendrocyte precursor: 142.3;oligodendrocyte: 551.4" "Group enriched" "Detected in some" 8 "Glioblastoma Multiforme (TCGA): 7.5;Thyroid Carcinoma (TCGA): 17.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Pituitary gland - Undifferentiated cells (Pituitary gland), Spleen - B-cells (Spleen), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA038569 Enhanced Uncertain Mitochondria NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 72: Neuronal - Signal transduction" "Cluster 80: Oligodendrocytes - Myelination" 1 Mitochondria "HPA038569: " "unprognostic (2.45e-2)" "unprognostic (4.31e-2)" "unprognostic (4.19e-1)" "potential prognostic favorable (1.42e-4)" "unprognostic (1.71e-2)" "unprognostic (1.60e-1)" "unprognostic (7.26e-2)" "unprognostic (3.61e-1)" "unprognostic (3.59e-2)" "unprognostic (2.27e-3)" CARS1 CARS ENSG00000110619 "Cysteinyl-tRNA synthetase 1" P49589 11 3000922-3057613 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Cancer-related genes, Disease variant, Dwarfism, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 91.6;Late primary spermatocytes: 101.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002383, HPA002384, CAB075734, CAB075735, CAB075736, CAB075737" Enhanced Enhanced Cytosol NA NA 140000 "Cluster 33: Non-specific - ATP binding" "Cluster 24: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 102: Non-specific - Mixed function" 4 Cytosol "CAB075734: , CAB075735: , CAB075736: , CAB075737: , HPA002383: , HPA002384: " "unprognostic (2.78e-1)" "unprognostic (2.65e-2)" "unprognostic (9.26e-2)" "unprognostic (3.36e-1)" "unprognostic (1.11e-1)" "unprognostic (2.16e-3)" "unprognostic (4.88e-3)" "unprognostic (4.56e-2)" "potential prognostic unfavorable (9.81e-4)" "unprognostic (1.58e-1)" "unprognostic (1.62e-2)" "unprognostic (3.52e-2)" "unprognostic (5.10e-3)" "unprognostic (3.84e-3)" "unprognostic (1.29e-2)" "unprognostic (7.08e-2)" "unprognostic (1.26e-1)" "unprognostic (7.04e-2)" "unprognostic (1.03e-1)" "unprognostic (1.22e-2)" "unprognostic (2.31e-2)" "unprognostic (1.20e-1)" "unprognostic (8.11e-2)" "unprognostic (2.78e-1)" "unprognostic (6.48e-2)" "unprognostic (1.29e-1)" "unprognostic (2.04e-1)" "potential prognostic unfavorable (5.43e-5)" "unprognostic (1.94e-1)" CARS2 FLJ12118 ENSG00000134905 "Cysteinyl-tRNA synthetase 2, mitochondrial" Q9HA77 13 110641412-110713603 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 440.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041776 Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - DNA binding" "Cluster 19: Non-specific - Unknown function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 8 "Nucleoplasm, Mitochondria" "HPA041776: " "unprognostic (4.13e-2)" "unprognostic (1.04e-1)" "unprognostic (2.46e-1)" "unprognostic (2.83e-2)" "unprognostic (1.23e-1)" "unprognostic (1.50e-1)" "unprognostic (9.70e-2)" "unprognostic (4.49e-2)" "potential prognostic unfavorable (1.01e-4)" "unprognostic (8.65e-2)" "potential prognostic favorable (3.39e-6)" "unprognostic (1.76e-1)" "unprognostic (1.39e-1)" "potential prognostic unfavorable (4.13e-5)" "unprognostic (1.37e-2)" "unprognostic (1.66e-3)" "unprognostic (6.65e-3)" "unprognostic (9.47e-2)" "unprognostic (2.08e-1)" "unprognostic (2.77e-1)" "unprognostic (1.90e-1)" "unprognostic (5.42e-2)" "unprognostic (1.33e-1)" "unprognostic (5.98e-2)" "unprognostic (3.74e-3)" "unprognostic (1.48e-1)" "unprognostic (7.24e-2)" "unprognostic (3.58e-2)" "unprognostic (1.30e-1)" "unprognostic (2.36e-1)" "unprognostic (4.83e-2)" CARTPT CART ENSG00000164326 "CART prepropeptide" Q16568 5 71719275-71721048 "FDA approved drug targets, Human disease related genes, Predicted secreted proteins" "Neuropeptide, Neurotransmitter" "FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 599.0" "Group enriched" "Detected in some" 7 "Adrenal medulla cells: 148.9;Late primary spermatocytes: 93.9;Other brain neurons: 100.6;Retinal amacrine cells: 224.1" "Group enriched" "Detected in many" 7 "hippocampal CA4: 269.3;thalamic excitatory: 361.5" "Cancer enriched" "Detected in many" 11 "Breast Invasive Carcinoma (TCGA): 355.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 10 "Neuroblastoma: 24.8" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "hippocampal formation: 307.9" "CAB025515, HPA046278, CAB079776" Enhanced Supported "Secreted to blood" Neuropeptide NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 98: Neurons - Neurotransmission & signaling" 6 "CAB025515: , CAB079776: , HPA046278: " "unprognostic (1.34e-1)" "unprognostic (2.62e-1)" "unprognostic (4.46e-2)" "unprognostic (3.86e-1)" "unprognostic (2.07e-2)" "unprognostic (1.02e-1)" "unprognostic (5.76e-2)" "unprognostic (2.91e-1)" "unprognostic (4.36e-2)" "potential prognostic unfavorable (3.21e-4)" "unprognostic (9.82e-2)" CASC3 "BTZ, MLN51" ENSG00000108349 "CASC3 exon junction complex subunit" O15234 17 40140318-40172171 "Cancer-related genes, Predicted intracellular proteins, Transporters" "mRNA processing, mRNA splicing, mRNA transport, Nonsense-mediated mRNA decay, Stress response, Translation regulation, Transport" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 229.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Prostate - Smooth muscle cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024592, HPA050262" Approved Supported "Nuclear membrane" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 50 "Nuclear membrane" "HPA024592: , HPA050262: " "unprognostic (1.84e-1)" "unprognostic (2.43e-2)" "unprognostic (7.94e-2)" "unprognostic (1.38e-3)" "unprognostic (2.12e-1)" "unprognostic (2.08e-2)" "unprognostic (2.16e-1)" "unprognostic (1.32e-2)" "unprognostic (2.62e-2)" "potential prognostic unfavorable (3.46e-4)" "potential prognostic favorable (9.27e-5)" "unprognostic (3.02e-3)" "unprognostic (3.12e-1)" "unprognostic (4.72e-2)" "potential prognostic unfavorable (2.99e-4)" "unprognostic (4.63e-2)" "unprognostic (2.52e-3)" "unprognostic (2.50e-1)" "potential prognostic favorable (2.14e-4)" "unprognostic (3.64e-2)" "unprognostic (1.82e-2)" "unprognostic (1.82e-1)" "unprognostic (1.49e-3)" "unprognostic (2.53e-1)" "unprognostic (1.35e-3)" "unprognostic (5.99e-3)" "unprognostic (2.04e-1)" "unprognostic (5.38e-2)" "unprognostic (1.41e-1)" "unprognostic (7.19e-2)" "unprognostic (6.53e-2)" CASD1 "C7orf12, FLJ21213, FLJ21879" ENSG00000127995 "CAS1 domain containing 1" Q96PB1 7 94509219-94557019 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Corticotrophs: 252.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044404, HPA052908" Approved Approved Nucleoplasm Yes No "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 39: Non-specific - Transcription" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" Nucleoplasm "HPA044404: , HPA052908: " "unprognostic (1.48e-1)" "unprognostic (1.80e-1)" "unprognostic (1.58e-1)" "unprognostic (2.72e-2)" "unprognostic (2.10e-1)" "unprognostic (2.63e-1)" "unprognostic (1.34e-1)" "unprognostic (2.28e-3)" "unprognostic (3.12e-1)" "unprognostic (2.69e-3)" "potential prognostic favorable (1.66e-5)" "unprognostic (1.78e-1)" "unprognostic (1.06e-1)" "unprognostic (6.89e-2)" "unprognostic (7.55e-3)" "unprognostic (3.75e-2)" "unprognostic (5.40e-2)" "unprognostic (3.06e-1)" "unprognostic (2.47e-1)" "unprognostic (3.83e-2)" "unprognostic (2.13e-2)" "unprognostic (6.99e-2)" "unprognostic (2.24e-2)" "unprognostic (1.83e-1)" "unprognostic (1.47e-1)" "unprognostic (2.61e-2)" "unprognostic (6.26e-2)" "unprognostic (1.56e-2)" "unprognostic (2.16e-1)" "unprognostic (1.22e-1)" "unprognostic (8.15e-2)" CASK "CAGH39, FGS4, LIN2, TNRC8" ENSG00000147044 "Calcium/calmodulin dependent serine protein kinase" O14936 X 41514934-41923554 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte progenitor cells: 686.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 46.8" "Lineage enriched" "Detected in many" 10 "granulocytes: 46.8" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skin - Outer root sheath cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001949, HPA023857" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 77: Intestine - Digestion" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 36: Non-specific - mRNA processing" "Cluster 9: T-cells - Adaptive immunity: Regulation" 53 Nucleoplasm Cytosol "CAB001949: , HPA023857: " "unprognostic (1.03e-1)" "unprognostic (1.11e-1)" "unprognostic (6.70e-2)" "unprognostic (3.24e-2)" "unprognostic (6.41e-2)" "unprognostic (2.48e-1)" "unprognostic (2.55e-1)" "unprognostic (2.14e-3)" "unprognostic (2.47e-1)" "unprognostic (2.54e-3)" "unprognostic (1.28e-3)" "unprognostic (2.04e-1)" "potential prognostic unfavorable (2.57e-4)" "unprognostic (1.38e-3)" "unprognostic (9.92e-2)" "unprognostic (8.23e-2)" "unprognostic (2.82e-2)" "unprognostic (9.07e-2)" "unprognostic (3.13e-1)" "unprognostic (4.67e-2)" "unprognostic (2.12e-2)" "potential prognostic unfavorable (8.53e-4)" "unprognostic (2.96e-2)" "unprognostic (1.62e-1)" "unprognostic (3.15e-2)" "unprognostic (4.76e-2)" "unprognostic (1.21e-1)" "unprognostic (8.68e-2)" "unprognostic (2.64e-2)" "unprognostic (4.54e-2)" "unprognostic (1.32e-1)" CASKIN1 "ANKS5A, KIAA1306" ENSG00000167971 "CASK interacting protein 1" Q8WXD9 16 2177180-2196605 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "brain: 57.3" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 21.3;Astrocytes: 68.7;Bergmann glia: 46.2;Brain excitatory neurons: 34.1;Brain inhibitory neurons: 44.7;Epicardial cells: 34.1;Müller glia: 57.4;Oligodendrocyte progenitor cells: 43.7;Other brain neurons: 35.2;Retinal amacrine cells: 58.5;Retinal bipolar cells: 27.5;Retinal ganglion cells: 65.7;Retinal horizontal cells: 52.1" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Glioblastoma Multiforme (TCGA): 3.7;Prostate Adenocarcinoma (TCGA): 6.3;Uterine Corpus Endometrial Carcinoma (TCGA): 11.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 5.0" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055990, HPA076882, CAB079050" Enhanced Supported Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 109: Neurons - Neuronal signaling" 2 Nucleoplasm "Nuclear bodies, Cytosol" "CAB079050: , HPA055990: , HPA076882: " "unprognostic (2.24e-1)" "unprognostic (2.00e-1)" "unprognostic (4.78e-2)" "unprognostic (1.53e-1)" "unprognostic (2.28e-1)" "unprognostic (5.11e-3)" "unprognostic (7.46e-2)" "unprognostic (3.09e-1)" "unprognostic (1.92e-1)" CASKIN2 "ANKS5B, FLJ21609, KIAA1139" ENSG00000177303 "CASK interacting protein 2" Q8WXE0 17 75500261-75515537 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Lymphatic endothelial cells: 43.3;Müller glia: 26.2;Oligodendrocyte progenitor cells: 29.7;Vascular endothelial cells: 75.1" "Cell type enhanced" "Detected in many" "endothelial cell: 43.8;oligodendrocyte precursor cell: 28.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Lung - Endothelial cells, Minor Salivary Gland - Endothelial cells, Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA071906, HPA075184" Enhanced Supported "Plasma membrane" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "Plasma membrane" "HPA071906: , HPA075184: " "unprognostic (7.46e-3)" "unprognostic (1.71e-1)" "unprognostic (2.58e-2)" "unprognostic (9.24e-2)" "unprognostic (3.91e-2)" "unprognostic (2.28e-1)" "unprognostic (4.91e-2)" "unprognostic (7.71e-3)" "unprognostic (1.10e-1)" "unprognostic (3.65e-1)" "validated prognostic favorable (2.84e-8)" "validated prognostic favorable (4.96e-5)" "unprognostic (7.71e-3)" "unprognostic (7.42e-2)" "unprognostic (1.53e-2)" "unprognostic (2.44e-2)" "unprognostic (1.76e-1)" "unprognostic (8.96e-2)" "unprognostic (1.25e-2)" "unprognostic (2.15e-1)" "unprognostic (1.66e-1)" "potential prognostic favorable (6.55e-5)" "unprognostic (9.90e-2)" "unprognostic (5.95e-2)" "unprognostic (3.12e-1)" "unprognostic (3.15e-2)" "unprognostic (1.03e-1)" "unprognostic (1.92e-1)" "unprognostic (2.95e-1)" "unprognostic (1.53e-1)" "unprognostic (2.88e-1)" CASP1 "ICE, IL1BC" ENSG00000137752 "Caspase 1" P29466 11 105025397-105035250 "Cancer-related genes, Enzymes, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 122.0;lymphoid tissue: 87.0" "Cell type enhanced" "Detected in many" "cDC: 113.2;Enteric transient amplifying cells: 83.5;Enterocytes: 94.8;Esophageal basal cells: 56.1;Hofbauer cells: 134.6;Kupffer cells: 117.9;Macrophages: 76.0;Monocyte progenitors: 67.1;monocytes: 165.4;Neutrophils: 134.4" "Group enriched" "Detected in some" 5 "central nervous system macrophage: 38.9;endothelial cell: 12.0;leukocyte: 43.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Thyroid gland - T-cells" "Region enhanced" "Detected in all" "olfactory bulb: 18.4" "Low region specificity" "Detected in all" "CAB002685, HPA003056" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 5: Spleen - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 25 Cytosol Nucleoplasm "CAB002685: , HPA003056: " "unprognostic (1.29e-1)" "unprognostic (3.38e-3)" "unprognostic (3.10e-1)" "unprognostic (2.51e-1)" "unprognostic (1.37e-1)" "unprognostic (1.03e-2)" "unprognostic (3.66e-2)" "unprognostic (1.35e-1)" "unprognostic (7.01e-2)" "unprognostic (7.03e-2)" "unprognostic (1.01e-1)" "unprognostic (2.00e-1)" "unprognostic (2.36e-1)" "unprognostic (5.67e-3)" "unprognostic (1.01e-1)" "unprognostic (2.16e-2)" "unprognostic (2.54e-1)" "unprognostic (8.38e-3)" "unprognostic (1.91e-1)" "unprognostic (1.48e-1)" "unprognostic (2.87e-1)" "unprognostic (1.16e-2)" "unprognostic (6.29e-2)" "unprognostic (1.33e-1)" "unprognostic (3.04e-2)" "unprognostic (1.47e-2)" "unprognostic (2.46e-1)" "unprognostic (1.25e-1)" "unprognostic (5.25e-3)" "unprognostic (4.59e-1)" "unprognostic (2.75e-2)" CASP10 "FLICE-2, MCH4" ENSG00000003400 "Caspase 10" Q92851 2 201182872-201229428 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 66.8;Esophageal apical cells: 73.8;Neutrophil progenitors: 125.5;Neutrophils: 65.4;Ocular epithelial cells: 63.0;Plasma cells: 137.8;Urothelial cells: 63.4" "Group enriched" "Detected in many" 10 "central nervous system macrophage: 77.3;endothelial cell: 170.8;leukocyte: 55.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Myeloma: 31.0" "Breast - Endothelial cells, Skeletal muscle - Endothelial cells, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "CAB003780, HPA017059" Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 21 "Golgi apparatus" Vesicles "CAB003780: , HPA017059: " "unprognostic (5.76e-3)" "unprognostic (3.90e-2)" "unprognostic (3.52e-3)" "unprognostic (2.36e-1)" "unprognostic (5.63e-2)" "unprognostic (3.68e-2)" "unprognostic (1.82e-1)" "unprognostic (3.41e-1)" "unprognostic (1.29e-1)" "unprognostic (7.60e-2)" "unprognostic (9.56e-3)" "unprognostic (9.08e-3)" "unprognostic (7.65e-2)" "potential prognostic unfavorable (2.75e-4)" "unprognostic (6.01e-2)" "unprognostic (2.00e-2)" "unprognostic (1.11e-1)" "unprognostic (2.63e-1)" "unprognostic (2.38e-1)" "unprognostic (3.69e-2)" "unprognostic (2.91e-1)" "unprognostic (1.02e-1)" "unprognostic (2.06e-1)" "unprognostic (4.75e-1)" "unprognostic (7.22e-3)" "unprognostic (2.09e-1)" "unprognostic (1.03e-3)" "unprognostic (4.67e-2)" "unprognostic (1.12e-1)" "unprognostic (1.38e-1)" "unprognostic (1.43e-2)" CASP12 CASP12P1 ENSG00000204403 "Caspase 12 (gene/pseudogene)" 11 104885718-104898670 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "ovary: 7.4" "Cell type enhanced" "Detected in some" "Adipocytes: 4.0;Cardiomyocytes: 18.0;Fibro-adipogenic progenitors: 4.3;Fibroblasts: 3.3;Lymphatic endothelial cells: 21.9;Ovarian stromal cells: 4.8;Vascular endothelial cells: 8.4" "Cell type enhanced" "Detected in some" "endothelial cell: 25.8;fibroblast: 12.0;pericyte: 16.0" "Region enriched" "Detected in many" 6 "cerebellum: 11.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Fibroblasts_1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 35: Non-specific - DNA binding" "Cluster 61: BICR 18 - Protein kinases" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" CASP14 "MGC119078, MGC119079, MICE" ENSG00000105141 "Caspase 14" P31944 19 15049480-15058293 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Differentiation "Hydrolase, Protease, Thiol protease" Ichthyosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "skin 1: 458.8" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 11.2;Extravillous trophoblasts: 5.6;Late spermatids: 6.2;Ocular epithelial cells: 23.8;Suprabasal keratinocytes: 64.8" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Bladder Urothelial Carcinoma (TCGA): 104.3;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 122.4;Head and Neck Squamous Cell Carcinoma (TCGA): 37.6;Skin Cutaneous Melanoma (TCGA): 82.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "breast cancer: 18.2" "Skin - Keratinocyte (other), Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "CAB010059, HPA027062" Enhanced Supported Nucleoplasm,Mitochondria,Cytosol NA NA 18000000 "Cluster 37: Skin - Keratinization" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 26: Keratinocytes - Keratinization" 25 "Nucleoplasm, Cytosol" Mitochondria "CAB010059: , HPA027062: " "unprognostic (1.62e-1)" "unprognostic (1.40e-3)" "unprognostic (1.19e-1)" "unprognostic (4.15e-2)" "unprognostic (3.34e-1)" "potential prognostic unfavorable (2.55e-4)" "unprognostic (4.51e-2)" "unprognostic (1.42e-2)" "unprognostic (4.50e-2)" "unprognostic (2.79e-2)" "validated prognostic unfavorable (6.14e-4)" "validated prognostic unfavorable (6.41e-4)" "unprognostic (5.98e-2)" "unprognostic (1.09e-1)" "unprognostic (3.00e-1)" "unprognostic (1.76e-2)" CASP2 "ICH1, MGC2181, NEDD2, PPP1R57" ENSG00000106144 "Caspase 2" P42575 7 143288215-143307696 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes, Disease variant, Intellectual disability, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 78.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006938, CAB012175, HPA050678" Approved Supported Mitochondria NA Yes "Cluster 5: Non-specific - Cell proliferation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 11: White matter - Signal transduction" "Cluster 39: Non-specific - Transcription" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 16 Mitochondria "CAB012175: , HPA006938: , HPA050678: " "unprognostic (3.63e-2)" "unprognostic (9.04e-2)" "unprognostic (5.02e-2)" "unprognostic (1.27e-1)" "unprognostic (1.04e-2)" "unprognostic (9.51e-3)" "unprognostic (1.03e-1)" "unprognostic (1.38e-1)" "unprognostic (7.10e-3)" "unprognostic (3.35e-3)" "unprognostic (4.11e-2)" "unprognostic (1.50e-2)" "unprognostic (1.52e-1)" "potential prognostic unfavorable (1.14e-4)" "unprognostic (3.68e-3)" "unprognostic (2.39e-3)" "unprognostic (8.94e-3)" "unprognostic (1.29e-1)" "unprognostic (2.09e-1)" "unprognostic (5.41e-3)" "unprognostic (1.28e-1)" "unprognostic (5.43e-3)" "unprognostic (1.87e-2)" "unprognostic (7.18e-2)" "unprognostic (6.61e-2)" "unprognostic (2.64e-1)" "unprognostic (6.43e-3)" "unprognostic (1.83e-2)" "unprognostic (1.78e-1)" "unprognostic (3.75e-2)" "unprognostic (1.74e-1)" CASP3 "apopain, CPP32, CPP32B, Yama" ENSG00000164305 "Caspase 3" P42574 4 184627696-184650062 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Innate lymphoid cells: 164.7;Megakaryocyte-Erythroid progenitors: 163.5;Plasma cells: 151.3;Platelets: 224.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "basophil: 491.1;eosinophil: 332.6" "Lineage enriched" "Detected in all" 8 "granulocytes: 491.1" "Low cancer specificity" "Detected in all" "Spleen - Mitotic cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000091, HPA002643, CAB008381" Enhanced Approved Nucleoplasm,Mitochondria NA NA 300000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 25: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 44: Plasma cells - Antibody production & secretion" 55 Mitochondria Nucleoplasm "CAB000091: , CAB008381: , HPA002643: " "potential prognostic favorable (8.17e-4)" "unprognostic (1.10e-1)" "unprognostic (3.65e-1)" "unprognostic (2.43e-1)" "unprognostic (1.73e-3)" "unprognostic (9.91e-3)" "unprognostic (8.15e-3)" "unprognostic (2.62e-2)" "unprognostic (5.42e-2)" "unprognostic (3.87e-1)" "unprognostic (2.58e-2)" "unprognostic (2.85e-1)" "unprognostic (1.38e-1)" "potential prognostic unfavorable (4.54e-4)" "unprognostic (1.75e-2)" "unprognostic (4.68e-3)" "unprognostic (2.82e-2)" "unprognostic (8.66e-3)" "unprognostic (1.92e-1)" "unprognostic (1.49e-1)" "unprognostic (1.03e-2)" "unprognostic (2.74e-3)" "unprognostic (2.11e-1)" "unprognostic (2.13e-1)" "unprognostic (3.72e-2)" "unprognostic (2.14e-1)" "unprognostic (9.97e-2)" "unprognostic (5.75e-2)" "unprognostic (1.12e-1)" "unprognostic (3.27e-1)" "unprognostic (3.41e-1)" CASP4 "ICE(rel)II, ICH-2, TX" ENSG00000196954 "Caspase 4" P49662 11 104942866-104969366 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Immunity, Inflammatory response, Innate immunity, Necrosis" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 510.1;Neutrophils: 661.7;Platelets: 229.8" "Group enriched" "Detected in some" 5 "Bergmann glia: 22.1;central nervous system macrophage: 44.2;endothelial cell: 78.1;fibroblast: 44.4;leukocyte: 77.8;pericyte: 22.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Colon - Endothelial cells, Skeletal muscle - Endothelial cells" "HPA027588, CAB037167" Approved Approved "Plasma membrane,Cytosol" "Intracellular and membrane" Immunity NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 24: Neutrophils - Innate immunity signal integration" 3 Cytosol "Plasma membrane" "CAB037167: , HPA027588: " "unprognostic (3.14e-2)" "unprognostic (2.63e-2)" "unprognostic (3.66e-2)" "unprognostic (2.22e-1)" "unprognostic (2.59e-1)" "unprognostic (2.24e-2)" "potential prognostic unfavorable (2.46e-4)" "unprognostic (1.13e-3)" "unprognostic (3.06e-2)" "unprognostic (1.76e-2)" "potential prognostic unfavorable (9.03e-4)" "unprognostic (2.40e-1)" "unprognostic (1.37e-1)" "unprognostic (3.18e-3)" "unprognostic (2.22e-1)" "unprognostic (5.71e-2)" "unprognostic (2.52e-2)" "unprognostic (8.18e-3)" "unprognostic (2.14e-2)" "unprognostic (2.24e-1)" "unprognostic (2.30e-1)" "potential prognostic unfavorable (5.95e-5)" "unprognostic (6.68e-3)" "unprognostic (5.45e-2)" "unprognostic (1.98e-1)" "unprognostic (9.34e-2)" "unprognostic (1.20e-1)" "unprognostic (1.60e-1)" "unprognostic (4.50e-2)" "unprognostic (2.85e-2)" "unprognostic (1.34e-1)" CASP5 ICE(rel)III ENSG00000137757 "Caspase 5" P51878 11 104994235-105023168 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "intestine: 15.8;lymphoid tissue: 13.8" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 34.3;Colonocytes: 30.4;Enteric transient amplifying cells: 9.9;Enterocytes: 21.4;Goblet cells: 8.5;monocytes: 10.9;Neutrophils: 80.5;Paneth cells: 19.3" "Group enriched" "Detected in some" 6 "central nervous system macrophage: 3.5;leukocyte: 5.2" "Group enriched" "Detected in some" 6 "Colon Adenocarcinoma (TCGA): 7.3;Rectum Adenocarcinoma (TCGA): 6.7;Stomach Adenocarcinoma (TCGA): 2.2" "Group enriched" "Detected in some" 5 "cerebral cortex: 9.1;pons: 2.3" "Group enriched" "Detected in some" 13 "intermediate monocyte: 18.1;neutrophil: 13.0;non-classical monocyte: 41.4" "Group enriched" "Detected in many" 15 "granulocytes: 13.0;monocytes: 41.4" "Cancer enriched" "Detected in single" 5 "colorectal cancer: 2.4" "Adipose visceral - Neutrophils" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 77: Intestine - Digestion" "Cluster 12: Non-specific - Vasculature" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 24: Neutrophils - Innate immunity signal integration" "unprognostic (2.93e-1)" "unprognostic (3.13e-2)" "unprognostic (1.27e-2)" "unprognostic (5.16e-1)" "unprognostic (2.42e-2)" "unprognostic (3.17e-2)" "unprognostic (6.56e-2)" "unprognostic (1.32e-3)" "unprognostic (1.31e-1)" "unprognostic (1.73e-3)" "unprognostic (2.74e-2)" CASP6 MCH2 ENSG00000138794 "Caspase 6" P55212 4 109688622-109703583 "Cancer-related genes, Enzymes, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 38.1" "Cell type enhanced" "Detected in many" "Enteric stem cells: 101.4;Enteric transient amplifying cells: 95.5;Megakaryocytes: 111.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003775, HPA011337, HPA024303" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA 4500 "Cluster 6: T-cells - T-cell receptor" "Cluster 77: Intestine - Digestion" "Cluster 34: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 130 Cytosol "Nucleoplasm, Nucleoli fibrillar center" "CAB003775: , HPA011337: , HPA024303: " "unprognostic (8.62e-2)" "unprognostic (2.27e-1)" "unprognostic (4.11e-2)" "unprognostic (5.89e-2)" "unprognostic (5.29e-3)" "unprognostic (1.26e-3)" "unprognostic (5.39e-2)" "unprognostic (3.26e-3)" "unprognostic (1.69e-1)" "unprognostic (1.76e-3)" "unprognostic (1.77e-1)" "unprognostic (6.35e-2)" "unprognostic (2.94e-1)" "unprognostic (9.09e-3)" "unprognostic (1.82e-2)" "unprognostic (1.19e-2)" "unprognostic (2.35e-2)" "unprognostic (3.25e-1)" "unprognostic (1.38e-1)" "unprognostic (2.47e-2)" "unprognostic (2.52e-1)" "unprognostic (2.43e-2)" "unprognostic (4.47e-2)" "unprognostic (8.33e-2)" "potential prognostic favorable (4.80e-4)" "unprognostic (6.54e-2)" "unprognostic (1.17e-1)" "unprognostic (3.24e-2)" "unprognostic (1.70e-1)" "unprognostic (3.54e-2)" "unprognostic (4.83e-2)" CASP7 "CMH-1, ICE-LAP3, MCH3" ENSG00000165806 "Caspase 7" P55210 10 113679162-113730907 "Cancer-related genes, Enzymes, Predicted intracellular proteins" Apoptosis "Allosteric enzyme, Hydrolase, Protease, RNA-binding, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 160.8;Enterocytes: 103.4;Foveolar cells: 134.8" "Group enriched" "Detected in many" 6 "astrocyte: 25.6;Bergmann glia: 31.7;central nervous system macrophage: 13.1;choroid plexus epithelial cell: 15.4;endothelial cell: 25.6;ependymal cell: 25.0;fibroblast: 19.2;leukocyte: 28.8;pericyte: 19.5;vascular associated smooth muscle cell: 19.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025563, HPA069167" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Plasma membrane" "Intracellular and membrane" Enzyme NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 77: Intestine - Digestion" "Cluster 39: Astrocytes - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 31 "Nucleoplasm, Nucleoli fibrillar center" "Plasma membrane" "CAB025563: , HPA069167: " "unprognostic (1.45e-1)" "unprognostic (3.86e-3)" "unprognostic (1.31e-1)" "unprognostic (2.28e-1)" "unprognostic (6.86e-3)" "unprognostic (1.22e-1)" "unprognostic (3.47e-1)" "unprognostic (1.82e-2)" "unprognostic (2.77e-1)" "unprognostic (2.03e-2)" "potential prognostic favorable (3.20e-6)" "unprognostic (1.70e-2)" "unprognostic (2.02e-2)" "potential prognostic unfavorable (8.33e-4)" "unprognostic (1.29e-2)" "unprognostic (6.09e-2)" "unprognostic (3.59e-1)" "unprognostic (1.79e-1)" "unprognostic (1.22e-1)" "unprognostic (2.67e-1)" "unprognostic (4.43e-2)" "unprognostic (4.61e-2)" "unprognostic (3.47e-1)" "unprognostic (1.85e-2)" "unprognostic (1.65e-1)" "unprognostic (1.33e-2)" "unprognostic (1.59e-1)" "unprognostic (5.39e-3)" "unprognostic (7.36e-2)" "unprognostic (2.24e-1)" "unprognostic (1.45e-1)" CASP8 "Casp-8, FLICE, MACH, MCH5" ENSG00000064012 "Caspase 8" Q14790 2 201233443-201361836 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Host-virus interaction" "Hydrolase, Protease, Thiol protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 44.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 381.6;Innate lymphoid cells: 190.3;Neutrophils: 238.4;NK-cells: 214.4;T-cells: 224.6;Thymocytes: 205.0" "Group enriched" "Detected in all" 4 "central nervous system macrophage: 49.1;leukocyte: 145.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001302, CAB002047, HPA005688" Approved Uncertain "Centriolar satellite,Mitochondria,Cytosol,Connecting piece,Mid piece,Principal piece" NA No "Cluster 35: Neutrophils - Protein binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 9: T-cells - Adaptive immunity: Regulation" 83 "Mitochondria, Cytosol" "Centriolar satellite, Connecting piece, Mid piece, Principal piece" "CAB002047: , HPA001302: , HPA005688: " "potential prognostic favorable (5.84e-5)" "unprognostic (2.35e-1)" "unprognostic (7.58e-2)" "potential prognostic unfavorable (5.48e-4)" "unprognostic (4.38e-2)" "unprognostic (3.82e-2)" "unprognostic (1.98e-1)" "unprognostic (4.35e-3)" "unprognostic (2.69e-2)" "unprognostic (5.33e-3)" "unprognostic (5.07e-2)" "unprognostic (2.88e-1)" "unprognostic (3.81e-2)" "unprognostic (1.72e-3)" "unprognostic (1.47e-1)" "unprognostic (3.44e-2)" "unprognostic (4.89e-3)" "unprognostic (3.88e-1)" "unprognostic (1.79e-1)" "unprognostic (1.26e-1)" "unprognostic (3.28e-1)" "unprognostic (4.43e-2)" "unprognostic (2.07e-2)" "unprognostic (2.71e-2)" "unprognostic (3.74e-2)" "unprognostic (2.13e-2)" "unprognostic (6.33e-3)" "unprognostic (1.04e-1)" "unprognostic (4.11e-1)" "unprognostic (4.44e-2)" "unprognostic (2.03e-1)" CASP8AP2 "CED-4, FLASH, FLJ11208, KIAA1315, RIP25" ENSG00000118412 "Caspase 8 associated protein 2" 6 89829894-89874436 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "Astrocytes: 34.6;Bergmann glia: 40.6;Brain excitatory neurons: 40.4;Brain inhibitory neurons: 39.1;Choroid plexus epithelial cells: 44.0;Distal convoluted tubule cells: 48.2;Ependymal cells: 30.8;Loop of henle epithelial cells: 48.1;Microglia: 49.8;Oligodendrocyte progenitor cells: 38.1;Oligodendrocytes: 45.8;Other brain neurons: 31.0;Papillary tip epithelial cells: 35.9;Podocytes: 49.0;Proximal tubule cells: 44.6;Renal collecting duct intercalated cells: 43.9;Renal collecting duct principal cells: 38.8;Renal connecting tubule cells: 41.7" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053573 Approved "Nucleoli,Nuclear bodies" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 16: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 102: Non-specific - Mixed function" 6 "Nucleoli, Nuclear bodies" "HPA053573: " "potential prognostic unfavorable (7.14e-4)" "unprognostic (7.76e-2)" "unprognostic (3.05e-2)" "unprognostic (1.80e-1)" "unprognostic (2.46e-2)" "potential prognostic unfavorable (9.21e-4)" "unprognostic (7.95e-2)" CASP9 "APAF-3, ICE-LAP6, MCH6, PPP1R56" ENSG00000132906 "Caspase 9" P55211 1 15490832-15526534 "Cancer-related genes, Enzymes, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 88.1;Somatotrophs: 91.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001473, CAB004348, HPA046488" Approved Approved Mitochondria NA NA "Cluster 41: Basophils - Unknown function" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 103: Non-specific - Basic cellular processes" 29 Mitochondria "CAB004348: , HPA001473: , HPA046488: " "unprognostic (4.01e-2)" "unprognostic (3.61e-2)" "unprognostic (2.38e-1)" "unprognostic (1.57e-1)" "unprognostic (1.50e-3)" "unprognostic (2.58e-1)" "unprognostic (1.66e-2)" "potential prognostic favorable (1.28e-4)" "unprognostic (2.84e-3)" "unprognostic (3.74e-2)" "unprognostic (1.37e-1)" "unprognostic (1.52e-3)" "unprognostic (7.67e-3)" "unprognostic (1.04e-3)" "unprognostic (3.83e-2)" "unprognostic (1.60e-1)" "unprognostic (1.52e-1)" "unprognostic (1.07e-1)" "unprognostic (1.06e-1)" "unprognostic (4.00e-1)" "unprognostic (2.74e-1)" "unprognostic (7.73e-2)" "unprognostic (3.45e-1)" "unprognostic (1.94e-1)" "unprognostic (4.39e-1)" "unprognostic (1.37e-1)" "unprognostic (9.24e-2)" "unprognostic (3.34e-2)" "unprognostic (1.50e-1)" "unprognostic (4.30e-2)" "unprognostic (3.02e-3)" CASQ1 "CASQ, PDIB1" ENSG00000143318 "Calsequestrin 1" P31415 1 160190575-160201886 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Muscle protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 64 "skeletal muscle: 4161.9;tongue: 1767.3" "Group enriched" "Detected in some" 4 "Myonuclei: 182.0;Thymic myoid cells: 47.6" "Cell type enhanced" "Detected in many" "Bergmann glia: 4.2" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 9.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 2.8;testis cancer: 3.1" "Heart muscle - Cardiomyocytes, Pituitary gland - Undifferentiated cells (Pituitary gland), Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA007845, CAB015170, HPA026823" Enhanced Approved Nucleoplasm,Mitochondria "Intracellular and membrane" Other NA NA 7800 "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 51: Neurons - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 1 "Nucleoplasm, Mitochondria" "CAB015170: , HPA007845: , HPA026823: " "unprognostic (6.38e-2)" "unprognostic (4.00e-2)" "unprognostic (2.96e-1)" "unprognostic (1.43e-1)" "unprognostic (7.78e-3)" "unprognostic (7.96e-2)" "unprognostic (1.82e-2)" "unprognostic (2.39e-2)" "unprognostic (9.26e-2)" "unprognostic (9.00e-2)" CASQ2 PDIB2 ENSG00000118729 "Calsequestrin 2" O14958 1 115700021-115768714 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Muscle protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "heart muscle: 989.2" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 300.7;Early spermatids: 51.3;Myonuclei: 277.7;Smooth muscle cells: 134.7;Thymic myoid cells: 779.1;Vascular smooth muscle cells: 219.6" "Group enriched" "Detected in some" 21 "thalamic excitatory: 59.6;vascular associated smooth muscle cell: 223.7" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 8.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Sarcoma: 2.6" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Adrenal gland - Smooth muscle cells, Breast - Endothelial cells, Colon - Smooth muscle cells, Heart muscle - Cardiomyocytes, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Skin - Smooth muscle cells, Spleen - Smooth muscle cells, Thyroid gland - Smooth muscle cells" "Region enriched" "Detected in all" 6 "cerebellum: 43.1" "Low region specificity" "Detected in many" "HPA027285, HPA055298" Enhanced "Intracellular and membrane" Other NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 11 "HPA027285: , HPA055298: " "unprognostic (3.47e-3)" "unprognostic (9.38e-2)" "unprognostic (1.07e-1)" "unprognostic (5.88e-3)" "unprognostic (6.36e-2)" "unprognostic (1.57e-2)" "potential prognostic unfavorable (4.68e-4)" "validated prognostic favorable (3.87e-6)" "validated prognostic favorable (3.14e-7)" "unprognostic (2.23e-2)" "unprognostic (1.39e-1)" "unprognostic (1.59e-1)" "unprognostic (1.80e-1)" "unprognostic (1.23e-2)" "unprognostic (6.89e-2)" "unprognostic (5.16e-2)" "unprognostic (8.35e-2)" "unprognostic (8.09e-3)" "unprognostic (2.39e-1)" "unprognostic (3.48e-1)" CASR "FHH, GPRC2A, HHC, HHC1, NSHPT" ENSG00000036828 "Calcium sensing receptor" P41180 3 122183668-122291629 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Plasma proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 29 "parathyroid gland: 615.6" "Group enriched" "Detected in some" 4 "Distal convoluted tubule cells: 579.9;Loop of henle epithelial cells: 537.7" "Cell type enriched" "Detected in some" 16 "midbrain-derived inhibitory: 136.0" "Cancer enhanced" "Detected in some" "Kidney Chromophobe (TCGA): 3.9;Pancreatic Adenocarcinoma (TCGA): 8.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "thyroid cancer: 7.0" "Kidney - Ascending Loop of Henle cells, Pancreas - Beta cells, Stomach - Gastric enteroendocrine cells, Thyroid gland - Parafollicular cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA039686, HPA050335" Enhanced NA NA "Cluster 69: Parathyroid gland - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 9 "HPA039686: , HPA050335: " "unprognostic (2.25e-3)" "unprognostic (1.41e-1)" "unprognostic (8.25e-3)" "unprognostic (2.81e-1)" "unprognostic (1.61e-1)" "unprognostic (1.26e-1)" "unprognostic (1.86e-2)" CASS4 "C20orf32, HEFL, HEPL" ENSG00000087589 "Cas scaffold protein family member 4" Q9NQ75 20 56412112-56460387 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lung: 11.1;lymphoid tissue: 9.1" "Cell type enriched" "Detected in many" 4 "Neutrophils: 390.3" "Group enriched" "Detected in many" 13 "central nervous system macrophage: 91.6;endothelial cell: 82.4;leukocyte: 31.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "eosinophil: 23.1;neutrophil: 69.1" "Lineage enriched" "Detected in many" 10 "granulocytes: 69.1" "Group enriched" "Detected in some" 7 "Leukemia: 4.6;Sarcoma: 2.2" "Adrenal gland - Macrophages, Kidney - Fibroblasts, Minor Salivary Gland - Macrophages, Skin - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB034217 Approved NA NA 290000 "Cluster 21: Neutrophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 44: Non-specific - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" "CAB034217: " "unprognostic (1.91e-2)" "unprognostic (1.19e-1)" "unprognostic (1.61e-1)" "unprognostic (1.90e-1)" "unprognostic (1.68e-1)" "unprognostic (3.18e-1)" "unprognostic (1.75e-2)" "unprognostic (6.17e-2)" "unprognostic (2.05e-1)" "potential prognostic favorable (1.64e-4)" "unprognostic (1.02e-1)" "unprognostic (1.43e-2)" "unprognostic (2.34e-1)" "unprognostic (1.08e-1)" "unprognostic (1.33e-1)" "unprognostic (1.08e-1)" "unprognostic (5.34e-2)" "unprognostic (2.59e-2)" "unprognostic (6.40e-2)" CAST ENSG00000153113 Calpastatin P20810 5 96525267-96779595 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Thiol protease inhibitor" "Cancer-related genes, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 3885.9;Ocular epithelial cells: 2239.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009491, HPA036881, HPA036882, HPA075906" Enhanced Enhanced "Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA 7900000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 5 "Endoplasmic reticulum, Cytosol" "Plasma membrane" "CAB009491: , HPA036881: , HPA036882: , HPA075906: " "unprognostic (1.94e-1)" "unprognostic (1.81e-1)" "unprognostic (2.15e-1)" "unprognostic (1.25e-2)" "unprognostic (1.73e-2)" "unprognostic (1.21e-1)" "unprognostic (1.11e-1)" "potential prognostic unfavorable (8.12e-5)" "unprognostic (1.86e-1)" "unprognostic (1.85e-2)" "potential prognostic favorable (3.50e-6)" "unprognostic (1.63e-1)" "unprognostic (8.21e-2)" "unprognostic (2.26e-1)" "unprognostic (5.14e-2)" "unprognostic (3.16e-3)" "unprognostic (3.28e-3)" "unprognostic (1.59e-2)" "unprognostic (1.14e-2)" "unprognostic (5.36e-3)" "unprognostic (4.24e-3)" "potential prognostic unfavorable (3.07e-5)" "unprognostic (5.23e-2)" "unprognostic (3.97e-2)" "unprognostic (1.81e-2)" "unprognostic (1.38e-2)" "unprognostic (9.78e-3)" "unprognostic (1.34e-2)" "unprognostic (7.65e-2)" "unprognostic (4.52e-1)" "unprognostic (4.42e-1)" CASTOR1 GATSL3 ENSG00000239282 "Cytosolic arginine sensor for mTORC1 subunit 1" Q8WTX7 22 30285117-30289622 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 50.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 88.4;Esophageal apical cells: 88.0;Esophageal suprabasal cells: 68.4;Extravillous trophoblasts: 78.4;Migrating cytotrophoblasts: 47.0;Pituicytes/FSCs: 23.6;Syncytiotrophoblasts: 35.8" "Cell type enhanced" "Detected in many" "astrocyte: 21.5;Bergmann glia: 24.4;endothelial cell: 15.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073183 Approved NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 19: Astrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 16 "HPA073183: " "potential prognostic unfavorable (7.27e-4)" "unprognostic (1.11e-1)" "unprognostic (6.78e-3)" "unprognostic (4.44e-2)" "unprognostic (6.47e-2)" "unprognostic (2.80e-2)" "unprognostic (7.28e-3)" "unprognostic (8.35e-2)" "unprognostic (5.38e-2)" "unprognostic (1.49e-1)" "unprognostic (3.76e-3)" "unprognostic (3.50e-1)" "unprognostic (5.86e-2)" "unprognostic (2.62e-1)" "unprognostic (3.22e-1)" "unprognostic (3.77e-2)" "unprognostic (1.38e-1)" "unprognostic (3.75e-1)" "unprognostic (1.27e-2)" "unprognostic (3.56e-2)" "unprognostic (5.93e-2)" "unprognostic (1.59e-2)" "unprognostic (3.46e-1)" "unprognostic (6.37e-2)" "unprognostic (3.72e-2)" "unprognostic (1.31e-1)" "unprognostic (3.06e-2)" "unprognostic (4.37e-2)" "unprognostic (1.65e-2)" CASTOR2 "GATSL1, GATSL2" ENSG00000274070 "Cytosolic arginine sensor for mTORC1 subunit 2" A6NHX0 7 74964705-75031528 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 61.7" "Cell type enhanced" "Detected in many" "Myonuclei: 108.5;Retinal horizontal cells: 106.2;Syncytiotrophoblasts: 103.2;Thymic myoid cells: 106.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 33.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057229 Approved NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 5 "HPA057229: " "unprognostic (2.01e-1)" "unprognostic (3.79e-2)" "unprognostic (3.17e-2)" "unprognostic (1.72e-3)" "unprognostic (1.22e-1)" "unprognostic (4.23e-2)" "unprognostic (7.25e-2)" "unprognostic (1.49e-2)" "unprognostic (1.91e-1)" "unprognostic (1.89e-3)" "unprognostic (1.39e-2)" "unprognostic (1.16e-3)" "unprognostic (9.64e-2)" "unprognostic (3.64e-1)" "unprognostic (9.88e-3)" "unprognostic (2.15e-3)" "unprognostic (1.08e-2)" "potential prognostic favorable (8.27e-5)" "unprognostic (1.60e-2)" "unprognostic (8.12e-2)" "unprognostic (1.82e-1)" "unprognostic (9.12e-2)" "unprognostic (2.46e-1)" "unprognostic (9.39e-2)" "unprognostic (1.13e-1)" "unprognostic (3.79e-1)" CASZ1 "castor, cst, FLJ20321, SRG, ZNF693" ENSG00000130940 "Castor zinc finger 1" Q86V15 1 10636604-10796650 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 46.8" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 892.2;Myonuclei: 333.0;Podocytes: 297.6;Prostatic glandular cells: 332.3;Rod photoreceptor cells: 1091.4" "Cell type enhanced" "Detected in many" "eccentric medium spiny neuron: 51.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Breast - Breast glandular cells, Stomach - Gastric mucous cells, Testis - Spermatogonia" "Low region specificity" "Detected in some" "HPA028222, HPA029927" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 49: Non-specific - Transcription" "Cluster 36: Choroid plexus - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 79: Photoreceptor cells - Phototransduction" 4 Nucleoplasm "Vesicles, Cytosol" "HPA028222: , HPA029927: " "unprognostic (9.95e-3)" "unprognostic (1.05e-1)" "unprognostic (2.96e-1)" "unprognostic (2.22e-1)" "unprognostic (2.49e-2)" "unprognostic (4.89e-1)" "unprognostic (1.02e-1)" "unprognostic (4.60e-2)" "unprognostic (8.07e-2)" "unprognostic (1.68e-1)" "unprognostic (4.06e-2)" "unprognostic (1.22e-2)" "unprognostic (4.93e-2)" "potential prognostic unfavorable (1.47e-5)" "unprognostic (6.78e-2)" "potential prognostic favorable (8.08e-4)" "unprognostic (1.39e-1)" "unprognostic (2.24e-1)" "unprognostic (7.92e-2)" "unprognostic (4.05e-2)" "unprognostic (1.25e-2)" "unprognostic (2.15e-1)" "unprognostic (1.33e-1)" "unprognostic (1.85e-1)" "unprognostic (1.24e-1)" "unprognostic (3.14e-1)" "unprognostic (8.41e-2)" "unprognostic (7.53e-2)" "unprognostic (9.95e-2)" "unprognostic (8.81e-3)" "unprognostic (2.27e-1)" CAT ENSG00000121691 Catalase P04040 11 34438934-34472060 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrogen peroxide" "Mitogen, Oxidoreductase, Peroxidase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1138.3" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 463.3;Hepatocytes: 581.5;Megakaryocyte-Erythroid progenitors: 305.0;Neutrophil progenitors: 333.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 13 "eosinophil: 4747.5" "Lineage enriched" "Detected in all" 13 "granulocytes: 4747.5" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Liver - Hepatocytes, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001515, HPA051282, HPA055838" Enhanced Enhanced Vesicles NA NA 320000000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 21 Vesicles "CAB001515: , HPA051282: , HPA055838: " "unprognostic (1.07e-1)" "unprognostic (1.37e-1)" "unprognostic (1.44e-2)" "unprognostic (3.05e-1)" "unprognostic (8.02e-3)" "unprognostic (2.12e-1)" "unprognostic (1.91e-2)" "unprognostic (1.51e-1)" "unprognostic (3.41e-2)" "unprognostic (1.82e-1)" "potential prognostic favorable (9.28e-10)" "unprognostic (4.37e-3)" "unprognostic (1.62e-1)" "unprognostic (1.44e-3)" "potential prognostic favorable (1.21e-4)" "unprognostic (1.35e-3)" "unprognostic (2.42e-1)" "unprognostic (2.14e-2)" "unprognostic (9.91e-2)" "unprognostic (3.93e-3)" "unprognostic (1.45e-2)" "unprognostic (1.08e-2)" "unprognostic (1.72e-2)" "unprognostic (1.93e-1)" "unprognostic (3.47e-3)" "unprognostic (2.91e-2)" "unprognostic (2.74e-1)" "unprognostic (4.75e-2)" "unprognostic (7.36e-2)" "unprognostic (8.88e-2)" "unprognostic (1.65e-1)" CATIP "C2orf62, MGC50811" ENSG00000158428 "Ciliogenesis associated TTC17 interacting protein" Q7Z7H3 2 218356857-218368099 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 15.4;fallopian tube: 18.9" "Group enriched" "Detected in many" 4 "Choroid plexus epithelial cells: 29.9;Endometrial ciliated cells: 42.0;Ependymal cells: 74.6;Epididymal efferent duct ciliated cells: 78.1;Fallopian tube ciliated cells: 111.4;Late primary spermatocytes: 37.1;Late spermatids: 31.4;Respiratory ciliated cells: 113.4" "Group enriched" "Detected in many" 12 "choroid plexus epithelial cell: 25.4;ependymal cell: 80.3" "Cancer enhanced" "Detected in some" "Kidney Renal Papillary Cell Carcinoma (TCGA): 8.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Bile duct cancer: 1.4" "Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Spleen - Neutrophils_2, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA044818 Supported Approved "Connecting piece,Mid piece" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 34: Testis cancer - Unknown function" "Cluster 107: Ciliated cells - Cilia assembly & function" 14 "Connecting piece" "Mid piece" "HPA044818: " "validated prognostic favorable (3.97e-5)" "validated prognostic favorable (7.01e-5)" "potential prognostic favorable (5.74e-5)" "unprognostic (3.35e-2)" "unprognostic (3.37e-2)" "unprognostic (3.98e-2)" "unprognostic (1.80e-1)" "unprognostic (1.93e-1)" "unprognostic (5.71e-2)" CATSPER1 CATSPER ENSG00000175294 "Cation channel sperm associated 1" Q8NEC5 11 66016752-66026479 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Calcium transport, Differentiation, Ion transport, Spermatogenesis, Transport" "Calcium channel, Developmental protein, Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 33 "testis: 16.5" "Cell type enhanced" "Detected in some" "Early spermatids: 42.9;Extravillous trophoblasts: 9.8;Late primary spermatocytes: 36.9;Mast cells: 47.1;Megakaryocytes: 12.4;monocytes: 18.2;NK-cells: 12.1;Platelets: 36.6" "Cell type enhanced" "Detected in some" "leukocyte: 1.1;vascular associated smooth muscle cell: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "basophil: 16.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Macrophages, Minor Salivary Gland - Macrophages, Spleen - Neutrophils_2, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA044528 Supported "Principal piece" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 23: Testis - Spermatogenesis" "Cluster 72: Neuronal - Signal transduction" "Cluster 58: Mast cells - Allergic inflammatory responses" 97 "Principal piece" "HPA044528: " "unprognostic (3.46e-1)" "potential prognostic unfavorable (6.38e-5)" CATSPER2 ENSG00000166762 "Cation channel sperm associated 2" Q96P56 15 43628503-43668118 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Differentiation, Ion transport, Spermatogenesis, Transport" "Calcium channel, Developmental protein, Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 21.4;testis: 14.9" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 154.4;Cone photoreceptor cells: 196.7;Corticotrophs: 142.5;Rod photoreceptor cells: 306.3;Sertoli cells: 144.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA042709 Uncertain "Vesicles,Plasma membrane,Primary cilium,Principal piece,End piece" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 2: Neurons - Nucleosome" "Cluster 56: Non-specific - Sensory perception" "Cluster 79: Photoreceptor cells - Phototransduction" 1 "End piece" "Vesicles, Plasma membrane, Primary cilium, Principal piece" "HPA042709: " "unprognostic (2.19e-2)" "unprognostic (4.12e-1)" "unprognostic (2.24e-2)" "unprognostic (2.48e-1)" "unprognostic (3.81e-2)" "unprognostic (2.28e-2)" "unprognostic (3.36e-2)" "unprognostic (2.20e-2)" "unprognostic (4.00e-2)" "unprognostic (3.28e-1)" "unprognostic (4.31e-2)" "unprognostic (3.56e-1)" "unprognostic (2.25e-2)" "unprognostic (1.05e-1)" "unprognostic (1.13e-1)" "unprognostic (2.24e-1)" "unprognostic (2.77e-1)" "unprognostic (3.08e-2)" "unprognostic (5.95e-3)" "unprognostic (3.89e-2)" "unprognostic (6.50e-3)" "unprognostic (5.75e-2)" "unprognostic (2.30e-3)" "unprognostic (5.09e-2)" "unprognostic (1.71e-1)" "unprognostic (1.05e-1)" "unprognostic (1.58e-2)" "unprognostic (2.30e-1)" CATSPER3 CACRC ENSG00000152705 "Cation channel sperm associated 3" Q86XQ3 5 134967907-135011696 "Predicted membrane proteins, Transporters" "Calcium transport, Differentiation, Ion transport, Spermatogenesis, Transport" "Calcium channel, Developmental protein, Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "testis: 28.0" "Group enriched" "Detected in some" 36 "Early spermatids: 201.6;Late primary spermatocytes: 145.1;Late spermatids: 79.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "naive B-cell: 1.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in single" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA049004, HPA067379" Enhanced "Mid piece,Principal piece" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 56: Non-specific - Sensory perception" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" "Mid piece, Principal piece" "HPA049004: , HPA067379: " "unprognostic (2.22e-1)" "unprognostic (1.74e-1)" "unprognostic (2.76e-2)" "unprognostic (3.32e-2)" "unprognostic (9.28e-2)" "unprognostic (9.98e-3)" "unprognostic (1.27e-3)" "unprognostic (1.35e-1)" CATSPER4 ENSG00000188782 "Cation channel sperm associated 4" Q7RTX7 1 26190561-26202968 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Differentiation, Ion transport, Spermatogenesis, Transport" "Calcium channel, Developmental protein, Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 55 "testis: 11.0" "Group enriched" "Detected in some" 4 "Early spermatids: 54.5;Late primary spermatocytes: 66.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA045257 Enhanced NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" 1 "HPA045257: " CATSPERB "C14orf161, FLJ14298" ENSG00000133962 "Cation channel sperm associated auxiliary subunit beta" Q9H7T0 14 91580696-91780707 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "pancreas: 10.3" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 19.1;Early spermatids: 19.9;Ependymal cells: 13.2;Loop of henle epithelial cells: 29.6;Lymphatic endothelial cells: 19.9;Pancreatic acinar cells: 14.8;Papillary tip epithelial cells: 103.2;Proximal tubule cells: 19.6;Renal collecting duct intercalated cells: 27.3;Renal collecting duct principal cells: 88.4;Renal connecting tubule cells: 32.3" "Group enriched" "Detected in many" 4 "deep-layer corticothalamic and 6b: 20.4;ependymal cell: 26.1;leukocyte: 79.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA035134 Approved "Mid piece" NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 34: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 105: Non-specific - Mixed function" "Mid piece" "HPA035134: " "unprognostic (2.22e-1)" "unprognostic (3.09e-2)" "unprognostic (1.11e-1)" "unprognostic (1.66e-1)" "unprognostic (2.35e-1)" "unprognostic (8.27e-2)" "unprognostic (2.49e-2)" "unprognostic (2.29e-1)" "unprognostic (2.57e-2)" "unprognostic (2.63e-1)" "unprognostic (1.88e-1)" "unprognostic (1.37e-1)" "unprognostic (2.75e-2)" "unprognostic (3.63e-2)" "unprognostic (1.32e-2)" "unprognostic (1.97e-2)" CATSPERD "MGC39581, TMEM146" ENSG00000174898 "Cation channel sperm associated auxiliary subunit delta" Q86XM0 19 5720637-5778734 "Predicted membrane proteins, Transporters" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 82 "testis: 8.1" "Cell type enhanced" "Detected in many" "Early spermatids: 166.5;Endometrial ciliated cells: 91.2;Ependymal cells: 66.4;Epididymal efferent duct ciliated cells: 174.2;Fallopian tube ciliated cells: 250.7;Late primary spermatocytes: 52.8;Late spermatids: 219.1;Oocytes: 46.1;Respiratory ciliated cells: 249.1" "Cell type enriched" "Detected in many" 21 "ependymal cell: 95.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA024056 Enhanced Approved "Mid piece" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 47: Leukemia - Hemostasis" "Cluster 107: Ciliated cells - Cilia assembly & function" 5 "Mid piece" "HPA024056: " CATSPERE "C1orf101, MGC33370" ENSG00000179397 "Catsper channel auxiliary subunit epsilon" Q5SY80 1 244454377-244641177 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 20.1" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 120.6;Neutrophil progenitors: 119.1" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA077676 Supported "Mid piece,Principal piece,End piece,Annulus" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 37: Neutrophil progenitors - Granulopoiesis" "Mid piece, Principal piece, End piece" Annulus "HPA077676: " "unprognostic (1.76e-1)" CATSPERG "C19orf15, DKFZp434A1022, FLJ46353" ENSG00000099338 "Cation channel sperm associated auxiliary subunit gamma" Q6ZRH7 19 38335775-38370943 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "testis: 30.6" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 72.8;Enterocytes: 68.1;Late primary spermatocytes: 65.0;Late spermatids: 95.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "neutrophil: 1.5" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA052777 Approved "Mid piece,Principal piece" "Secreted in male reproductive system" "Developmental protein" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 67: Testis - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 65: Non-specific - Cell growth & division" "Mid piece" "Principal piece" "HPA052777: " "unprognostic (6.20e-1)" "unprognostic (1.06e-1)" "unprognostic (4.06e-3)" "unprognostic (1.29e-1)" "unprognostic (2.59e-1)" "unprognostic (5.36e-2)" CATSPERZ "C11orf20, DKFZP566E164, TEX40" ENSG00000219435 "Catsper channel auxiliary subunit zeta" Q9NTU4 11 64300358-64304770 "Predicted intracellular proteins, Transporters" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 152 "testis: 544.5" "Cell type enhanced" "Detected in some" "Early spermatids: 15.6;Late primary spermatocytes: 22.1;Late spermatids: 73.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA052822 Approved "Primary cilium tip,Cytosol,Mid piece,Principal piece" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 15: Non-specific - Transcription" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" "Primary cilium tip, Mid piece" "Cytosol, Principal piece" "HPA052822: " "unprognostic (5.44e-3)" "unprognostic (3.03e-1)" "unprognostic (6.84e-3)" "unprognostic (8.82e-2)" "unprognostic (1.46e-1)" "unprognostic (8.43e-2)" "unprognostic (9.27e-2)" "unprognostic (4.96e-2)" "unprognostic (2.39e-1)" CAV1 CAV ENSG00000105974 "Caveolin 1" Q03135 7 116524994-116561179 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" "Cancer-related genes, Congenital generalized lipodystrophy, Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 1960.5;Basal keratinocytes: 1117.4;Breast myoepithelial cells: 641.5;Extravillous trophoblasts: 572.4;Hepatic stellate cells: 555.1;Lymphatic endothelial cells: 762.4;Melanocytes: 538.0;Pericytes: 555.3;Peritubular myoid cells: 495.1;Smooth muscle cells: 1110.3;Transitional alveolar cells: 880.9;Vascular endothelial cells: 942.6;Vascular smooth muscle cells: 827.9" "Group enriched" "Detected in many" 12 "endothelial cell: 113.1;pericyte: 112.7;vascular associated smooth muscle cell: 329.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "basophil: 14.6;memory B-cell: 5.1" "Group enriched" "Detected in many" 57 "B-cells: 5.1;granulocytes: 14.6" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Alveolar cells type 1, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 169.0" "CAB003791, HPA049326, HPA059079" Enhanced Supported "Golgi apparatus,Perinuclear theca,Connecting piece,Principal piece" NA NA 4800 "Cluster 17: B-cells - Immunoglobulins" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 39: Non-specific - Transcription" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 126 "Golgi apparatus" "Perinuclear theca, Connecting piece, Principal piece" "CAB003791: , HPA049326: , HPA059079: " "unprognostic (8.95e-2)" "unprognostic (1.21e-1)" "unprognostic (1.41e-2)" "unprognostic (2.39e-3)" "unprognostic (1.47e-1)" "unprognostic (2.33e-1)" "unprognostic (3.53e-3)" "unprognostic (1.78e-2)" "unprognostic (2.08e-3)" "unprognostic (1.12e-1)" "unprognostic (5.46e-2)" "unprognostic (8.86e-3)" "unprognostic (4.64e-3)" "unprognostic (4.55e-2)" "unprognostic (2.41e-1)" "unprognostic (3.79e-2)" "unprognostic (3.35e-1)" "potential prognostic unfavorable (6.31e-4)" "unprognostic (1.73e-3)" "unprognostic (1.62e-1)" "unprognostic (2.52e-1)" "potential prognostic unfavorable (4.20e-4)" "unprognostic (1.05e-2)" "unprognostic (6.78e-2)" "unprognostic (2.11e-1)" "unprognostic (3.02e-2)" "unprognostic (2.65e-1)" "potential prognostic unfavorable (4.86e-4)" "unprognostic (2.34e-1)" "unprognostic (9.18e-2)" "unprognostic (3.14e-1)" CAV2 CAV ENSG00000105971 "Caveolin 2" P51636 7 116287380-116508541 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 213.4" "Cell type enhanced" "Detected in many" "Adipocytes: 1030.7;Alveolar cells type 1: 797.6;Basal keratinocytes: 417.3;Cardiomyocytes: 1401.7;Vascular smooth muscle cells: 371.0" "Group enriched" "Detected in many" 5 "endothelial cell: 88.1;pericyte: 93.5;vascular associated smooth muscle cell: 263.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 114 "basophil: 97.0" "Lineage enriched" "Detected in single" 433 "granulocytes: 97.0" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013488, HPA044810" Enhanced Approved Vesicles NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 27: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 89: Adipocytes - Lipid metabolism" 37 Vesicles "CAB013488: , HPA044810: " "unprognostic (9.28e-2)" "unprognostic (5.52e-2)" "unprognostic (1.54e-1)" "potential prognostic unfavorable (6.78e-4)" "unprognostic (5.26e-2)" "unprognostic (1.79e-2)" "unprognostic (1.02e-2)" "potential prognostic unfavorable (3.81e-4)" "potential prognostic unfavorable (9.06e-5)" "unprognostic (8.11e-2)" "unprognostic (1.66e-2)" "unprognostic (8.22e-2)" "unprognostic (6.11e-2)" "unprognostic (2.39e-2)" "unprognostic (4.63e-2)" "unprognostic (3.83e-2)" "unprognostic (3.14e-1)" "unprognostic (1.35e-1)" "unprognostic (4.32e-2)" "unprognostic (5.75e-2)" "unprognostic (1.85e-1)" "potential prognostic unfavorable (9.59e-6)" "unprognostic (1.65e-2)" "unprognostic (5.63e-2)" "unprognostic (1.60e-1)" "unprognostic (1.12e-1)" "unprognostic (7.84e-2)" "unprognostic (1.65e-2)" "unprognostic (2.24e-1)" "unprognostic (2.63e-1)" "unprognostic (7.19e-2)" CAV3 "LGMD1C, LQT9, VIP-21, VIP21" ENSG00000182533 "Caveolin 3" P56539 3 8733802-8841808 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cardiomyopathy, Disease variant, Limb-girdle muscular dystrophy, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "skeletal muscle: 171.2;tongue: 68.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 40.8;Early spermatids: 24.9;Epicardial cells: 40.9;Myonuclei: 77.4;Myosatellite cells: 19.0;Platelets: 19.8;Retinal ganglion cells: 34.8;Thymic myoid cells: 116.9" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in single" 4 "Head and Neck Squamous Cell Carcinoma (TCGA): 1.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 81 "Sarcoma: 13.9" "Adipose visceral - Smooth muscle cells, Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "CAB017518, CAB018557, HPA054488, HPA072988" Enhanced Approved "Vesicles,Plasma membrane" NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 7 "Plasma membrane" Vesicles "CAB017518: , CAB018557: , HPA054488: , HPA072988: " "unprognostic (1.69e-2)" CAVIN1 "cavin-1, CGL4, PTRF" ENSG00000177469 "Caveolae associated protein 1" Q6NZI2 17 42402449-42423256 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Transcription termination" "RNA-binding, rRNA-binding" "Congenital generalized lipodystrophy, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 483.2;Breast myoepithelial cells: 378.9;Hepatic stellate cells: 568.0;Leydig cells: 266.7;Lymphatic endothelial cells: 341.5;Pericytes: 311.9;Peritubular myoid cells: 412.9;Smooth muscle cells: 433.8;Vascular endothelial cells: 368.8;Vascular smooth muscle cells: 569.0" "Group enriched" "Detected in some" 5 "endothelial cell: 141.4;vascular associated smooth muscle cell: 266.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Colon - Smooth muscle cells, Minor Salivary Gland - Endothelial cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049838, HPA074213" Supported Supported "Vesicles,Plasma membrane" NA NA 300000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 30: White matter - Myelination" "Cluster 72: Neuronal - Signal transduction" "Cluster 62: Smooth muscle cells - Muscle contraction" 45 "Plasma membrane" Vesicles "HPA049838: , HPA074213: " "unprognostic (1.38e-1)" "unprognostic (1.48e-1)" "unprognostic (4.13e-2)" "unprognostic (3.56e-3)" "unprognostic (4.72e-2)" "unprognostic (1.08e-2)" "potential prognostic unfavorable (3.04e-5)" "unprognostic (1.11e-3)" "unprognostic (3.61e-2)" "unprognostic (1.31e-3)" "unprognostic (1.07e-3)" "unprognostic (7.67e-3)" "unprognostic (2.59e-2)" "unprognostic (5.45e-2)" "unprognostic (1.94e-2)" "unprognostic (4.72e-2)" "unprognostic (3.26e-1)" "unprognostic (2.05e-3)" "unprognostic (1.23e-2)" "unprognostic (3.66e-2)" "unprognostic (2.15e-1)" "unprognostic (1.24e-1)" "unprognostic (9.15e-2)" "unprognostic (5.06e-3)" "unprognostic (4.33e-2)" "unprognostic (2.86e-3)" "unprognostic (1.09e-1)" "unprognostic (2.39e-2)" "unprognostic (1.70e-1)" CAVIN2 "cavin-2, PS-p68, SDPR, SDR" ENSG00000168497 "Caveolae associated protein 2" O95810 2 191834310-191847088 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 154.8" "Group enriched" "Detected in many" 4 "Megakaryocytes: 1873.0;Platelets: 5719.2" "Group enriched" "Detected in some" 4 "endothelial cell: 237.5;fibroblast: 64.5" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 48.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 12 "basophil: 48.8;neutrophil: 24.3" "Lineage enriched" "Detected in many" 15 "granulocytes: 48.8" "Cancer enhanced" "Detected in many" "cervical cancer: 65.0" "Adrenal gland - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells, Liver - Sinusoid Endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039325, HPA062122" Enhanced Enhanced "Plasma membrane,Cytosol" Yes No 110000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 47: Platelets - Hemostasis" 9 "Plasma membrane" Cytosol "HPA039325: , HPA062122: " "unprognostic (2.07e-2)" "unprognostic (8.24e-3)" "unprognostic (1.25e-1)" "unprognostic (1.66e-1)" "unprognostic (5.34e-2)" "unprognostic (9.46e-2)" "unprognostic (1.45e-1)" "unprognostic (5.41e-2)" "unprognostic (7.79e-3)" "potential prognostic favorable (4.16e-11)" "unprognostic (1.10e-3)" "unprognostic (1.09e-1)" "unprognostic (5.63e-2)" "unprognostic (7.23e-3)" "unprognostic (1.28e-1)" "unprognostic (9.33e-2)" "unprognostic (4.55e-2)" "unprognostic (1.30e-1)" "unprognostic (1.62e-1)" "unprognostic (4.76e-2)" "unprognostic (3.06e-1)" "unprognostic (2.36e-1)" "unprognostic (2.51e-1)" "unprognostic (7.86e-3)" "unprognostic (9.38e-3)" "unprognostic (6.55e-3)" "unprognostic (8.69e-2)" "unprognostic (2.14e-1)" "unprognostic (6.66e-2)" CAVIN3 "cavin-3, HSRBC, MGC20400, PRKCDBP, SRBC" ENSG00000170955 "Caveolae associated protein 3" Q969G5 11 6318946-6320532 "Predicted intracellular proteins" "Biological rhythms" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 292.4" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 296.0;Fibroblasts: 148.6;Hepatic stellate cells: 290.5;Late primary spermatocytes: 813.1;Late spermatids: 291.9;Melanocytes: 212.0;Pericytes: 192.0;Schwann cells: 200.2;Smooth muscle cells: 243.1;Vascular smooth muscle cells: 430.7" "Group enriched" "Detected in many" 4 "pericyte: 113.3;vascular associated smooth muscle cell: 154.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 16.2;myeloid DC: 42.9" "Group enriched" "Detected in many" 5 "dendritic cells: 42.9;monocytes: 16.2" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Endothelial cells, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055136, HPA073327" Supported Approved "Plasma membrane" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 69: Skin cancer - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 32 "Plasma membrane" "HPA055136: , HPA073327: " "unprognostic (2.30e-1)" "unprognostic (6.03e-2)" "potential prognostic unfavorable (2.65e-4)" "unprognostic (4.80e-2)" "unprognostic (2.37e-2)" "unprognostic (6.53e-2)" "unprognostic (2.18e-2)" "unprognostic (2.52e-1)" "unprognostic (1.31e-1)" "unprognostic (1.08e-2)" "unprognostic (1.61e-3)" "potential prognostic favorable (4.87e-4)" "unprognostic (9.48e-3)" "potential prognostic unfavorable (7.11e-4)" "unprognostic (5.80e-2)" "unprognostic (1.88e-3)" "unprognostic (4.24e-2)" "unprognostic (1.27e-1)" "unprognostic (9.14e-2)" "unprognostic (6.61e-2)" "unprognostic (9.53e-2)" "unprognostic (1.13e-1)" "unprognostic (5.11e-2)" "unprognostic (5.13e-2)" "unprognostic (1.84e-2)" "unprognostic (2.08e-2)" "unprognostic (1.84e-1)" "unprognostic (1.09e-1)" "unprognostic (7.18e-2)" CAVIN4 "cavin-4, MURC" ENSG00000170681 "Caveolae associated protein 4" Q5BKX8 9 100578079-100588389 "Predicted intracellular proteins" "Differentiation, Myogenesis, Transcription, Transcription regulation" "Activator, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "skeletal muscle: 258.4;tongue: 86.3" "Group enriched" "Detected in many" 4 "Myonuclei: 172.6;Thymic myoid cells: 488.1" "Cell type enhanced" "Detected in many" "oligodendrocyte: 45.7" "Cancer enhanced" "Detected in some" "Head and Neck Squamous Cell Carcinoma (TCGA): 3.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 6.6" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA020973, HPA020987, HPA021021" Enhanced Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 6: Non-specific - Immune response" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 2 "Golgi apparatus, Plasma membrane" Nucleoplasm "HPA020973: , HPA020987: , HPA021021: " "potential prognostic favorable (5.15e-4)" "unprognostic (8.67e-3)" "unprognostic (1.78e-1)" CBARP "BARP, C19orf26, DOS, MGC40084" ENSG00000099625 "CACN subunit beta associated regulatory protein" Q8N350 19 1228287-1238027 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 16.7;pituitary gland: 19.8" "Cell type enhanced" "Detected in many" "Astrocytes: 24.4;Brain inhibitory neurons: 26.2;Early spermatids: 42.2;Lactotrophs: 83.4;Late primary spermatocytes: 147.6;Late spermatids: 132.4;Pituicytes/FSCs: 25.8;Somatotrophs: 75.9" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 6.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012777 Approved Nucleoplasm NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 12 Nucleoplasm "HPA012777: " "unprognostic (1.16e-1)" "unprognostic (3.22e-1)" "unprognostic (8.17e-2)" "unprognostic (9.11e-3)" "unprognostic (8.98e-3)" "unprognostic (2.37e-1)" "unprognostic (2.96e-2)" "unprognostic (5.93e-3)" CBFA2T2 "MTGR1, ZMYND3" ENSG00000078699 "CBFA2/RUNX1 partner transcriptional co-repressor 2" O43439 20 33490075-33650036 "Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060523, HPA072433" Supported Approved "Nuclear speckles" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 70: Intestinal goblet cells - Mucin production" 14 "Nuclear speckles" "HPA060523: , HPA072433: " "unprognostic (1.44e-2)" "unprognostic (6.92e-2)" "unprognostic (7.31e-2)" "unprognostic (3.32e-2)" "unprognostic (5.82e-2)" "unprognostic (2.47e-1)" "unprognostic (1.05e-1)" "unprognostic (1.55e-1)" "unprognostic (1.73e-3)" "unprognostic (1.17e-3)" "unprognostic (1.52e-1)" "unprognostic (6.63e-2)" "unprognostic (8.19e-3)" "unprognostic (2.46e-3)" "unprognostic (1.55e-1)" "unprognostic (1.02e-2)" "unprognostic (3.13e-1)" "unprognostic (2.00e-1)" "unprognostic (6.27e-2)" "unprognostic (4.37e-2)" "unprognostic (5.94e-2)" "unprognostic (1.32e-3)" "unprognostic (6.31e-2)" "unprognostic (3.65e-1)" "potential prognostic favorable (7.59e-5)" "unprognostic (5.33e-2)" "unprognostic (8.05e-2)" "unprognostic (2.52e-1)" "unprognostic (2.94e-1)" "unprognostic (8.27e-3)" "unprognostic (1.98e-1)" CBFA2T3 "ETO2, MTG16, MTGR2, RUNX1T3, ZMYND4" ENSG00000129993 "CBFA2/RUNX1 partner transcriptional co-repressor 3" O75081 16 88874858-88977207 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Differentiation, Transcription, Transcription regulation" Repressor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.7;lymphoid tissue: 27.4;pancreas: 25.8" "Cell type enhanced" "Detected in many" "B-cells: 49.1;cDC: 99.6;Erythrocyte progenitors: 56.7;Hematopoietic stem cells: 100.4;Megakaryocyte progenitors: 136.8;Megakaryocyte-Erythroid progenitors: 205.3;Megakaryocytes: 61.8;pDCs: 166.0;Platelets: 55.2;Thymocytes: 73.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 10.6" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Leukemia: 54.3;lymphoma: 29.3;Myeloma: 21.4" "Adipose visceral - Endothelial cells, Liver - Hepatocytes, Spleen - B-cells (Spleen), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059931, HPA062423, HPA065890" Approved Enhanced Nucleoplasm NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 47: Leukemia - Hemostasis" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 21 Nucleoplasm "HPA059931: , HPA062423: , HPA065890: " "unprognostic (7.22e-2)" "unprognostic (4.33e-1)" "unprognostic (1.71e-2)" "unprognostic (3.19e-3)" "unprognostic (3.71e-2)" "unprognostic (1.96e-1)" "unprognostic (2.12e-1)" "potential prognostic favorable (2.29e-4)" "unprognostic (5.77e-2)" "unprognostic (3.23e-3)" "potential prognostic favorable (3.40e-5)" "potential prognostic favorable (9.92e-5)" "unprognostic (2.10e-2)" "unprognostic (2.56e-2)" "unprognostic (8.81e-2)" "unprognostic (3.08e-2)" "unprognostic (4.55e-3)" "unprognostic (8.49e-2)" "unprognostic (8.98e-2)" "unprognostic (5.03e-2)" "unprognostic (1.22e-1)" "unprognostic (3.17e-2)" "unprognostic (3.02e-1)" "unprognostic (4.22e-1)" "unprognostic (1.22e-2)" CBFB PEBP2B ENSG00000067955 "Core-binding factor subunit beta" Q13951 16 67028984-67101058 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Dwarfism, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038852, HPA058730" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 32: Basophils - Transcription" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 11: White matter - Signal transduction" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 58: Mast cells - Allergic inflammatory responses" 20 "Nucleoplasm, Cytosol" "HPA038852: , HPA058730: " "unprognostic (5.42e-2)" "unprognostic (1.07e-1)" "unprognostic (7.11e-2)" "unprognostic (3.98e-3)" "unprognostic (7.33e-2)" "unprognostic (1.77e-3)" "unprognostic (9.05e-2)" "unprognostic (9.13e-2)" "unprognostic (4.32e-1)" "unprognostic (4.17e-2)" "potential prognostic favorable (5.81e-5)" "unprognostic (3.91e-2)" "unprognostic (1.53e-2)" "potential prognostic unfavorable (1.63e-4)" "unprognostic (1.75e-2)" "unprognostic (1.51e-1)" "unprognostic (5.98e-2)" "unprognostic (7.20e-3)" "unprognostic (1.72e-1)" "unprognostic (8.35e-2)" "unprognostic (2.72e-3)" "unprognostic (8.86e-3)" "unprognostic (1.01e-1)" "unprognostic (7.32e-2)" "unprognostic (4.73e-2)" "unprognostic (1.76e-1)" "unprognostic (1.30e-1)" "unprognostic (1.12e-1)" "unprognostic (1.17e-1)" "unprognostic (8.86e-2)" "unprognostic (2.16e-1)" CBL "c-Cbl, CBL2, RNF55" ENSG00000110395 "Cbl proto-oncogene" P22681 11 119206298-119313926 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophil progenitors: 368.6;Neutrophils: 711.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 8.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004350, HPA027956" Enhanced Supported "Mitotic spindle,Cytosol,End piece" Yes NA 160000 "Cluster 7: Non-specific - Innate immune response" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 19: Astrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" 201 Cytosol "Mitotic spindle, End piece" "CAB004350: , HPA027956: " "unprognostic (2.86e-2)" "unprognostic (9.42e-2)" "unprognostic (4.42e-1)" "unprognostic (4.47e-3)" "unprognostic (3.79e-1)" "unprognostic (3.63e-2)" "unprognostic (2.88e-2)" "unprognostic (1.18e-1)" "unprognostic (1.83e-1)" "potential prognostic unfavorable (5.63e-4)" "validated prognostic favorable (3.43e-4)" "validated prognostic favorable (7.67e-4)" "unprognostic (2.75e-2)" "unprognostic (2.08e-3)" "unprognostic (2.43e-1)" "unprognostic (1.49e-1)" "unprognostic (1.84e-3)" "unprognostic (1.35e-1)" "unprognostic (1.68e-1)" "unprognostic (1.96e-2)" "unprognostic (1.45e-3)" "unprognostic (2.46e-2)" "unprognostic (5.99e-3)" "unprognostic (5.03e-2)" "unprognostic (6.24e-2)" "unprognostic (5.49e-2)" "unprognostic (3.35e-2)" "unprognostic (8.38e-2)" "unprognostic (1.53e-1)" "unprognostic (8.97e-2)" "unprognostic (1.35e-1)" CBLB "Cbl-b, RNF56" ENSG00000114423 "Cbl proto-oncogene B" Q13191 3 105655461-105869552 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1315.0;Extravillous trophoblasts: 962.4;Fibro-adipogenic progenitors: 902.5;NK-cells: 1303.7;Podocytes: 2392.1;T-cells: 1313.7;Thymic myoid cells: 1195.1" "Cell type enhanced" "Detected in all" "leukocyte: 1170.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018327, HPA019880" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 57 Cytosol Nucleoplasm "HPA018327: , HPA019880: " "unprognostic (2.45e-1)" "unprognostic (1.03e-1)" "unprognostic (2.68e-2)" "unprognostic (7.01e-3)" "unprognostic (3.02e-1)" "unprognostic (3.21e-2)" "unprognostic (3.31e-2)" "unprognostic (2.66e-2)" "unprognostic (4.34e-2)" "unprognostic (4.03e-3)" "unprognostic (4.16e-2)" "unprognostic (1.78e-2)" "unprognostic (9.55e-2)" "unprognostic (7.42e-2)" "unprognostic (3.97e-2)" "unprognostic (7.15e-2)" "unprognostic (2.89e-3)" "unprognostic (1.31e-1)" "unprognostic (5.22e-2)" "unprognostic (1.32e-1)" "unprognostic (2.53e-1)" "unprognostic (3.74e-1)" "unprognostic (1.45e-2)" "unprognostic (4.36e-2)" "unprognostic (5.93e-2)" "unprognostic (2.52e-1)" "unprognostic (1.15e-1)" "unprognostic (1.88e-1)" "unprognostic (1.64e-1)" "unprognostic (3.15e-2)" "unprognostic (2.11e-1)" CBLC "CBL-3, CBL-SL, RNF57" ENSG00000142273 "Cbl proto-oncogene C" Q9ULV8 19 44777869-44800652 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 38.2;intestine: 47.9;skin 1: 40.7" "Cell type enhanced" "Detected in many" "Colonocytes: 160.4;Enteric stem cells: 82.7;Enteric transient amplifying cells: 103.4;Enterocytes: 208.1;Esophageal apical cells: 157.6;Esophageal basal cells: 84.4;Esophageal suprabasal cells: 152.3;Foveolar cells: 84.1;Ocular epithelial cells: 101.7;Paneth cells: 85.1;Prostatic hillock cells: 78.3;Suprabasal keratinocytes: 91.2;Urothelial cells: 140.4" "Cell type enhanced" "Detected in some" "CGE interneuron: 3.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" "CAB008087, HPA035266" Approved Approved Nucleoplasm,Aggresome NA NA "Cluster 77: Intestine - Digestion" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 69: Urothelial cells - Basic cellular functions" 20 Nucleoplasm Aggresome "CAB008087: , HPA035266: " "unprognostic (1.82e-1)" "unprognostic (2.60e-1)" "unprognostic (9.43e-2)" "unprognostic (1.43e-1)" "unprognostic (4.14e-2)" "unprognostic (1.40e-1)" "unprognostic (2.01e-2)" "unprognostic (2.45e-1)" "unprognostic (2.71e-1)" "unprognostic (2.87e-1)" "potential prognostic favorable (9.22e-4)" "unprognostic (1.90e-1)" "unprognostic (5.61e-2)" "unprognostic (1.91e-3)" "unprognostic (2.68e-1)" "unprognostic (2.91e-2)" "unprognostic (1.05e-1)" "unprognostic (5.41e-2)" "unprognostic (1.45e-2)" "unprognostic (9.98e-3)" "unprognostic (2.04e-1)" "unprognostic (1.90e-1)" "unprognostic (1.39e-1)" "unprognostic (1.45e-2)" "unprognostic (1.14e-1)" "unprognostic (3.53e-1)" "unprognostic (3.31e-2)" "unprognostic (2.29e-1)" CBLIF "GIF, IF, IFMH, INF, TCN3" ENSG00000134812 "Cobalamin binding intrinsic factor" P27352 11 59829273-59845499 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted secreted proteins" "Cobalt transport, Ion transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 2568 "stomach 1: 1485.0" "Cell type enriched" "Detected in some" 23 "Parietal cells: 6426.3" "Cell type enhanced" "Detected in some" "midbrain-derived inhibitory: 5.4" "Cancer enriched" "Detected in some" 9 "Stomach Adenocarcinoma (TCGA): 17.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "ovarian cancer: 1.0" "Stomach - Parietal cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA039908, HPA040774" Enhanced "Secreted to digestive system" Transport NA NA "Cluster 60: Stomach - Digestion" "Cluster 66: Non-specific - Mitochondria" "Cluster 97: Non-specific - Cellular respiration" 5 "HPA039908: , HPA040774: " "unprognostic (2.23e-3)" "unprognostic (2.21e-3)" "unprognostic (2.80e-2)" "unprognostic (2.72e-2)" "unprognostic (3.32e-1)" CBLL1 "FLJ23109, HAKAI, RNF188" ENSG00000105879 "Cbl proto-oncogene like 1" Q75N03 7 107743073-107761667 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Developmental protein, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021773, HPA026699" Enhanced Supported "Nuclear speckles" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 39: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 10 "Nuclear speckles" "HPA021773: , HPA026699: " "unprognostic (1.26e-2)" "unprognostic (1.41e-1)" "unprognostic (5.42e-2)" "unprognostic (3.16e-3)" "unprognostic (1.58e-1)" "unprognostic (4.24e-2)" "unprognostic (1.18e-1)" "unprognostic (3.18e-1)" "unprognostic (2.64e-2)" "unprognostic (1.37e-3)" "potential prognostic favorable (3.79e-7)" "unprognostic (9.88e-3)" "unprognostic (4.61e-1)" "unprognostic (2.96e-3)" "unprognostic (1.20e-2)" "unprognostic (8.23e-3)" "unprognostic (1.68e-2)" "unprognostic (5.48e-2)" "unprognostic (7.23e-2)" "potential prognostic unfavorable (3.95e-4)" "unprognostic (1.74e-3)" "unprognostic (1.30e-1)" "unprognostic (3.58e-2)" "unprognostic (1.57e-1)" "unprognostic (2.72e-2)" "unprognostic (1.45e-1)" "unprognostic (1.95e-2)" "unprognostic (1.70e-1)" "unprognostic (3.09e-1)" "unprognostic (1.16e-1)" "unprognostic (5.16e-2)" CBLL2 "CT138, FLJ25735, HAKAIL, ZNF645" ENSG00000175809 "Cbl proto-oncogene like 2" Q8N7E2 X 22272913-22274461 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 79 "testis: 7.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 28: Astrocytes - Homeostasis & neuron support" 14 CBLN1 ENSG00000102924 "Cerebellin 1 precursor" P23435 16 49277917-49281838 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "brain: 425.4" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 64.0;Early spermatids: 86.4;Late primary spermatocytes: 153.3;Late spermatids: 522.6" "Cell type enriched" "Detected in many" 12 "upper rhombic lip: 168.6" "Group enriched" "Detected in many" 4 "Testicular Germ Cell Tumor (TCGA): 8.0;Thyroid Carcinoma (TCGA): 15.5" "Region enriched" "Detected in all" 4 "cerebellum: 239.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 12.2;Neuroblastoma: 18.5" "Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in all" 9 "cerebellum: 613.4" "Region enriched" "Detected in all" 13 "cerebellum: 493.5" HPA056335 Approved "Cytosol,Perinuclear theca,Calyx,Flagellar centriole,Mid piece,Principal piece" "Secreted in brain" "No annotated function" NA NA 2100000 "Cluster 71: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 1: Neuronal - Visual perception" "Cluster 2: Cerebellar granular cells - Neuronal signaling" "Cytosol, Flagellar centriole, Mid piece, Principal piece" "Perinuclear theca, Calyx" "HPA056335: " "unprognostic (1.30e-1)" "unprognostic (6.76e-3)" "unprognostic (1.01e-1)" "unprognostic (1.14e-1)" "unprognostic (1.05e-1)" "potential prognostic favorable (2.69e-6)" "unprognostic (2.48e-2)" "unprognostic (1.94e-1)" "unprognostic (1.06e-1)" "unprognostic (3.37e-1)" "unprognostic (3.50e-1)" "unprognostic (7.33e-3)" "unprognostic (1.01e-2)" "unprognostic (1.91e-3)" "unprognostic (4.64e-1)" CBLN2 ENSG00000141668 "Cerebellin 2 precursor" Q8IUK8 18 72536680-72638521 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "brain: 38.4" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 120.5;Brain inhibitory neurons: 7.4;Epicardial cells: 22.7;Mesothelial cells: 35.1;Neuroendocrine cells: 13.8;Other brain neurons: 7.8;Retinal amacrine cells: 18.0;Somatotrophs: 9.0" "Cell type enhanced" "Detected in many" "deep-layer intratelencephalic: 310.4;hippocampal CA1-3: 530.6;upper-layer intratelencephalic: 623.5" "Cancer enriched" "Detected in many" 7 "Breast Invasive Carcinoma (TCGA): 10.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 36.9;Sarcoma: 13.5" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA056335 Approved "Cytosol,Perinuclear theca,Calyx,Flagellar centriole,Mid piece,Principal piece" "Secreted in brain" "No annotated function" NA NA 1200000 "Cluster 73: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" "Cytosol, Flagellar centriole, Mid piece, Principal piece" "Perinuclear theca, Calyx" "HPA056335: " "unprognostic (3.35e-2)" "unprognostic (6.84e-2)" "unprognostic (1.74e-1)" "unprognostic (1.98e-3)" "unprognostic (3.50e-3)" "unprognostic (9.90e-2)" "unprognostic (5.34e-1)" "unprognostic (9.51e-2)" "unprognostic (5.29e-2)" "potential prognostic unfavorable (6.45e-4)" CBLN3 ENSG00000139899 "Cerebellin 3 precursor" Q6UW01 14 24426545-24430954 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 23 "brain: 365.9" "Cell type enriched" "Detected in some" 7 "Brain excitatory neurons: 80.9" "Cell type enriched" "Detected in many" 18 "upper rhombic lip: 190.6" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 12 "cerebellum: 199.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 11.5" "Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Region enriched" "Detected in many" 25 "cerebellum: 429.9" "Region enriched" "Detected in many" 43 "cerebellum: 596.8" HPA041266 Enhanced Supported Approved Nucleoplasm "Secreted in brain" "No annotated function" NA NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 55: Lymphoma - Immune response" "Cluster 2: Cerebellar granular cells - Neuronal signaling" Nucleoplasm "HPA041266: " "unprognostic (6.43e-2)" "unprognostic (1.57e-1)" "unprognostic (2.66e-1)" "unprognostic (7.56e-2)" "unprognostic (5.37e-2)" "unprognostic (4.31e-1)" "unprognostic (3.63e-3)" "unprognostic (1.04e-3)" "unprognostic (1.56e-2)" "unprognostic (4.25e-3)" "unprognostic (8.44e-2)" "unprognostic (2.64e-2)" "unprognostic (1.46e-1)" "unprognostic (3.46e-2)" "unprognostic (1.33e-3)" "unprognostic (1.86e-2)" "unprognostic (4.41e-2)" "unprognostic (1.27e-1)" "unprognostic (1.47e-1)" "unprognostic (2.72e-1)" "unprognostic (2.90e-3)" "unprognostic (4.77e-2)" "unprognostic (1.05e-1)" "unprognostic (2.17e-1)" "unprognostic (1.80e-1)" "unprognostic (2.71e-2)" "unprognostic (5.23e-2)" "unprognostic (2.43e-2)" "unprognostic (9.78e-2)" "unprognostic (2.89e-2)" "unprognostic (7.16e-2)" CBLN4 "CBLNL1, dJ885A10.1" ENSG00000054803 "Cerebellin 4 precursor" Q9NTU7 20 55997357-56005519 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 16.8;brain: 15.6;epididymis: 8.3" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 15.5;Brain inhibitory neurons: 21.8;Epididymal basal cells: 20.9;Fibro-adipogenic progenitors: 7.4;Leydig cells: 4.8;Other brain neurons: 29.2;Peritubular myoid cells: 44.4" "Cell type enhanced" "Detected in many" "CGE interneuron: 72.3;midbrain-derived inhibitory: 49.9" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 2.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adrenal gland - Fibroblasts, Pituitary gland - Fibroblasts, Testis - Peritubular cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA056335, HPA074497" Supported Approved "Cytosol,Perinuclear theca,Calyx,Flagellar centriole,Mid piece,Principal piece" "Secreted in brain" "No annotated function" NA NA 9200000 "Cluster 36: Brain & Liver - Signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 11: Neuronal - Sensory perception" "Cluster 98: Neurons - Neurotransmission & signaling" 60 "Cytosol, Flagellar centriole, Mid piece, Principal piece" "Perinuclear theca, Calyx" "HPA056335: , HPA074497: " "unprognostic (1.10e-1)" "unprognostic (1.41e-1)" "unprognostic (2.89e-2)" "unprognostic (9.06e-2)" "unprognostic (2.32e-2)" "unprognostic (7.39e-3)" "unprognostic (4.23e-1)" "unprognostic (4.60e-2)" CBR1 "CBR, SDR21C1" ENSG00000159228 "Carbonyl reductase 1" P16152 21 36069941-36073166 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 378.9;intestine: 549.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 321.9;Enterocytes: 1118.0;Esophageal basal cells: 683.6;Esophageal suprabasal cells: 458.4;Hepatocytes: 321.1;Suprabasal keratinocytes: 355.7" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 154.6;oligodendrocyte: 207.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 422.3" "Liver - Hepatocytes, Minor Salivary Gland - Minor salivary gland basal cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018433, CAB034291" Enhanced Approved Nucleoplasm,Cytosol NA NA 4700000 "Cluster 25: Non-specific - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 11: White matter - Signal transduction" "Cluster 7: Liver cancer - Metabolism" "Cluster 1: Enterocytes - Absorption and Digestion" 24 Nucleoplasm Cytosol "CAB034291: , HPA018433: " "unprognostic (8.97e-3)" "unprognostic (3.18e-3)" "unprognostic (5.17e-2)" "unprognostic (9.15e-2)" "unprognostic (2.07e-1)" "unprognostic (4.26e-2)" "unprognostic (1.08e-2)" "potential prognostic unfavorable (8.91e-7)" "unprognostic (9.10e-2)" "unprognostic (2.70e-1)" "unprognostic (6.13e-3)" "unprognostic (1.17e-1)" "unprognostic (4.08e-1)" "unprognostic (1.34e-1)" "unprognostic (1.03e-3)" "unprognostic (1.63e-1)" "unprognostic (1.81e-1)" "unprognostic (8.55e-3)" "unprognostic (4.95e-2)" "unprognostic (2.08e-1)" "unprognostic (9.39e-2)" "unprognostic (6.98e-2)" "unprognostic (4.67e-3)" "unprognostic (2.18e-1)" "unprognostic (5.63e-3)" "unprognostic (3.68e-1)" "unprognostic (1.12e-1)" "unprognostic (1.68e-1)" "unprognostic (1.50e-1)" "unprognostic (2.71e-2)" "unprognostic (1.10e-1)" CBR3 SDR21C2 ENSG00000159231 "Carbonyl reductase 3" O75828 21 36135079-36146562 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 64.8;salivary gland: 46.3" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 150.5;Esophageal apical cells: 285.6;Esophageal basal cells: 205.5;Esophageal suprabasal cells: 375.5;Salivary acinar cells: 153.6;Salivary ionocytes: 178.0;Submucosal glandular cells: 130.5;Suprabasal keratinocytes: 227.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 9 "B-cells: 24.1;NK-cells: 11.5;T-cells: 33.8" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 105.4" "Spleen - Fibroblasts_1" "Region enhanced" "Detected in all" "basal ganglia: 48.6" "Low region specificity" "Detected in many" HPA018434 Uncertain Supported Nucleoplasm,Cytosol Yes NA 1200000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 15: Non-specific - Transcription" "Cluster 7: Liver cancer - Metabolism" "Cluster 85: Squamous epithelial cells - Keratinization" 11 "Nucleoplasm, Cytosol" "HPA018434: " "unprognostic (6.27e-3)" "unprognostic (2.83e-3)" "unprognostic (1.12e-1)" "unprognostic (2.96e-2)" "unprognostic (4.66e-2)" "unprognostic (8.75e-2)" "unprognostic (1.92e-1)" "unprognostic (2.64e-1)" "unprognostic (4.65e-3)" "unprognostic (6.20e-2)" "unprognostic (2.87e-3)" "unprognostic (2.47e-1)" "unprognostic (7.26e-2)" "unprognostic (6.73e-2)" "unprognostic (2.34e-1)" "unprognostic (6.24e-2)" "unprognostic (3.54e-3)" "unprognostic (2.43e-2)" "unprognostic (2.24e-1)" "unprognostic (2.10e-1)" "unprognostic (3.28e-2)" "unprognostic (1.75e-1)" "unprognostic (7.00e-3)" "unprognostic (2.73e-1)" "unprognostic (1.59e-1)" "unprognostic (9.44e-2)" "unprognostic (9.93e-2)" "unprognostic (1.29e-1)" "unprognostic (1.54e-1)" "unprognostic (2.37e-2)" "unprognostic (3.14e-2)" CBR4 "FLJ14431, SDR45C1" ENSG00000145439 "Carbonyl reductase 4" Q8N4T8 4 168863770-169010275 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 17 "Cardiomyocytes: 5958.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037499 Supported NA NA 200000 "Cluster 45: Eosinophils - Unknown function" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 21 "HPA037499: " "unprognostic (6.90e-3)" "unprognostic (1.25e-1)" "unprognostic (1.15e-1)" "unprognostic (1.52e-1)" "unprognostic (9.10e-2)" "unprognostic (2.79e-1)" "unprognostic (1.81e-1)" "unprognostic (6.79e-2)" "unprognostic (8.85e-3)" "unprognostic (3.04e-3)" "validated prognostic favorable (8.87e-7)" "validated prognostic favorable (1.15e-4)" "potential prognostic favorable (1.15e-7)" "unprognostic (8.80e-3)" "potential prognostic favorable (2.10e-6)" "unprognostic (1.22e-1)" "unprognostic (2.70e-1)" "unprognostic (1.12e-1)" "unprognostic (1.67e-2)" "unprognostic (2.10e-1)" "unprognostic (1.44e-1)" "unprognostic (4.36e-2)" "unprognostic (1.05e-1)" "unprognostic (6.72e-2)" "potential prognostic favorable (9.89e-4)" "unprognostic (9.79e-3)" "unprognostic (1.38e-1)" "unprognostic (3.53e-2)" "unprognostic (9.91e-3)" "unprognostic (3.73e-2)" "unprognostic (1.75e-1)" CBS HIP4 ENSG00000160200 "Cystathionine beta-synthase" P35520 21 43053191-43076943 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Cysteine biosynthesis" "Allosteric enzyme, Lyase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 177.4;pancreas: 128.1" "Group enriched" "Detected in some" 5 "Astrocytes: 4.3;Bergmann glia: 15.8;Breast lactating cells: 4.3;Enterocytes: 5.3;Epicardial cells: 4.5" "Group enriched" "Detected in some" 5 "astrocyte: 4.8;Bergmann glia: 13.7" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 76.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 65 "neutrophil: 6.5" "Lineage enriched" "Detected in single" 65 "granulocytes: 6.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001223 Enhanced Approved Nucleoli,Vesicles NA NA 810000 "Cluster 4: Neutrophils - Degranulation" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 25: Non-specific - Transcription" "Cluster 13: Non-specific - Mixed function" "Cluster 28: Astrocytes - Homeostasis & neuron support" 22 Vesicles Nucleoli "HPA001223: " "unprognostic (8.00e-2)" "unprognostic (1.06e-1)" "unprognostic (2.50e-2)" "unprognostic (5.48e-3)" "potential prognostic unfavorable (9.77e-4)" "unprognostic (1.03e-1)" "unprognostic (2.56e-1)" "unprognostic (4.57e-2)" "unprognostic (4.11e-1)" "unprognostic (1.49e-1)" "unprognostic (7.57e-2)" "unprognostic (1.99e-1)" "unprognostic (3.13e-2)" "potential prognostic favorable (6.10e-5)" "unprognostic (5.61e-3)" "unprognostic (1.00e-1)" "potential prognostic unfavorable (1.31e-5)" "unprognostic (3.00e-1)" "unprognostic (4.32e-2)" "unprognostic (3.27e-2)" "unprognostic (2.80e-1)" "unprognostic (2.37e-2)" "potential prognostic unfavorable (1.03e-5)" "unprognostic (8.93e-2)" "unprognostic (1.03e-2)" "unprognostic (2.69e-1)" "unprognostic (1.17e-1)" "unprognostic (5.64e-2)" "unprognostic (2.15e-1)" "unprognostic (8.59e-3)" "unprognostic (2.30e-3)" CBX1 "CBX, HP1-BETA, HP1Hs-beta, M31, MOD1" ENSG00000108468 "Chromobox 1" P83916 17 48070052-48101478 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 245.3;Early primary spermatocytes: 463.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012265, HPA071387" Supported Supported "Nucleoplasm,Nuclear bodies" NA NA 45000 "Cluster 7: Non-specific - Innate immune response" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 22: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 94: Gonadal somatic cells - Mixed function" 199 "Nucleoplasm, Nuclear bodies" "CAB012265: , HPA071387: " "unprognostic (8.38e-2)" "unprognostic (1.97e-2)" "unprognostic (3.73e-1)" "unprognostic (2.08e-1)" "unprognostic (3.81e-1)" "unprognostic (2.06e-2)" "unprognostic (3.95e-1)" "unprognostic (2.92e-3)" "unprognostic (2.76e-1)" "unprognostic (4.07e-2)" "potential prognostic favorable (5.75e-4)" "unprognostic (4.68e-3)" "potential prognostic unfavorable (5.86e-4)" "validated prognostic unfavorable (1.61e-5)" "validated prognostic unfavorable (2.03e-4)" "validated prognostic unfavorable (5.16e-4)" "validated prognostic unfavorable (1.55e-4)" "unprognostic (5.47e-2)" "potential prognostic favorable (2.75e-4)" "unprognostic (4.19e-1)" "potential prognostic unfavorable (5.70e-4)" "unprognostic (1.90e-1)" "unprognostic (1.89e-2)" "unprognostic (1.37e-2)" "unprognostic (4.70e-2)" "unprognostic (2.32e-2)" "unprognostic (4.63e-2)" "unprognostic (6.69e-2)" "unprognostic (2.86e-1)" "unprognostic (7.66e-2)" "unprognostic (6.36e-2)" CBX2 "CDCA6, M33, MGC10561" ENSG00000173894 "Chromobox 2" Q14781 17 79778148-79787983 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Sexual differentiation, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 6.8;testis: 12.3" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 20.2;Early spermatids: 37.4;Epididymal principal cells: 8.7;Hematopoietic stem cells: 19.9;Late primary spermatocytes: 10.0;Late spermatids: 67.4;Oocytes: 9.2;Thymocytes: 9.3;Undifferentiated spermatogonia: 14.2" "Cell type enhanced" "Detected in some" "endothelial cell: 2.7" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 39.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Neuroblastoma: 76.7" "Colon - Endothelial cells, Liver - Vascular endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA023083 Approved Supported Nucleoplasm NA NA "Cluster 39: Testis - Nuclear processes" "Cluster 47: Endothelial cells - Vasculature" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 42 Nucleoplasm "HPA023083: " "unprognostic (8.22e-2)" "unprognostic (2.84e-3)" "unprognostic (7.98e-2)" "unprognostic (1.49e-1)" "unprognostic (2.76e-1)" "unprognostic (9.32e-2)" "unprognostic (5.60e-2)" "unprognostic (2.49e-2)" "unprognostic (6.94e-2)" "unprognostic (8.34e-2)" "validated prognostic unfavorable (9.98e-13)" "validated prognostic unfavorable (1.05e-5)" "unprognostic (7.21e-3)" "unprognostic (1.54e-1)" "unprognostic (1.61e-1)" "unprognostic (2.79e-3)" "unprognostic (1.33e-2)" "unprognostic (4.85e-2)" "unprognostic (1.53e-2)" "unprognostic (4.11e-2)" "unprognostic (7.13e-2)" "unprognostic (2.18e-1)" "unprognostic (1.68e-1)" "unprognostic (3.39e-2)" "unprognostic (1.24e-1)" "unprognostic (1.59e-1)" "unprognostic (3.92e-2)" "unprognostic (7.54e-2)" CBX3 HP1Hs-gamma ENSG00000122565 "Chromobox 3" Q13185 7 26201162-26213607 "Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001973, HPA004902" Supported Supported "Nucleoplasm,Nuclear bodies" NA Yes 220000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 175 Nucleoplasm "Nuclear bodies" "CAB001973: , HPA004902: " "unprognostic (4.42e-1)" "unprognostic (5.67e-3)" "unprognostic (3.55e-2)" "potential prognostic unfavorable (2.74e-4)" "unprognostic (4.88e-2)" "unprognostic (2.99e-2)" "unprognostic (3.22e-2)" "unprognostic (2.87e-1)" "unprognostic (1.24e-2)" "potential prognostic unfavorable (7.36e-4)" "unprognostic (8.49e-3)" "unprognostic (8.87e-3)" "unprognostic (1.00e-1)" "validated prognostic unfavorable (2.41e-9)" "validated prognostic unfavorable (1.05e-6)" "potential prognostic unfavorable (6.15e-5)" "unprognostic (7.10e-3)" "unprognostic (1.34e-1)" "unprognostic (1.80e-1)" "unprognostic (6.72e-2)" "unprognostic (6.25e-2)" "potential prognostic unfavorable (1.77e-4)" "unprognostic (1.25e-3)" "unprognostic (4.04e-2)" "unprognostic (6.83e-2)" "unprognostic (3.54e-1)" "unprognostic (1.50e-2)" "unprognostic (2.54e-1)" "unprognostic (4.56e-2)" "unprognostic (1.26e-1)" "unprognostic (2.80e-1)" CBX4 "hPC2, NBP16, PC2" ENSG00000141582 "Chromobox 4" O00257 17 79833156-79839440 "Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Chromatin regulator, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "bone marrow: 123.0" "Cell type enhanced" "Detected in many" "Breast lactating cells: 232.5;Neutrophils: 181.8;pDCs: 136.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008228, HPA012021" Approved Enhanced "Nucleoplasm,Nuclear bodies" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 11: White matter - Signal transduction" "Cluster 13: Non-specific - Mixed function" "Cluster 20: Non-specific - Transcription regulation" 69 Nucleoplasm "Nuclear bodies" "HPA008228: , HPA012021: " "unprognostic (4.75e-2)" "unprognostic (3.49e-1)" "unprognostic (4.45e-2)" "unprognostic (4.87e-2)" "unprognostic (1.79e-1)" "unprognostic (6.14e-3)" "unprognostic (2.85e-1)" "unprognostic (5.06e-2)" "unprognostic (6.02e-2)" "unprognostic (6.93e-3)" "unprognostic (2.81e-3)" "unprognostic (1.79e-1)" "unprognostic (1.83e-2)" "unprognostic (1.43e-2)" "unprognostic (5.26e-2)" "unprognostic (9.01e-2)" "unprognostic (3.06e-1)" "unprognostic (6.22e-2)" "unprognostic (1.67e-2)" "unprognostic (5.67e-1)" "unprognostic (2.33e-2)" "unprognostic (1.55e-1)" "unprognostic (4.26e-2)" "unprognostic (3.30e-2)" "unprognostic (6.08e-2)" "unprognostic (5.60e-3)" "unprognostic (2.32e-1)" "unprognostic (1.14e-1)" "unprognostic (6.09e-2)" "unprognostic (1.20e-1)" "unprognostic (3.47e-1)" CBX5 "HP1, HP1-ALPHA, HP1Hs-alpha" ENSG00000094916 "Chromobox 5" P45973 12 54230942-54280133 "Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 112.0" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 510.8;Late primary spermatocytes: 311.6" "Cell type enriched" "Detected in all" 5 "choroid plexus epithelial cell: 557.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016699, CAB017548" Enhanced Enhanced Nucleoplasm NA NA 21000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 209 Nucleoplasm "CAB017548: , HPA016699: " "unprognostic (1.12e-1)" "unprognostic (4.94e-3)" "unprognostic (2.93e-2)" "unprognostic (2.64e-1)" "unprognostic (1.61e-2)" "unprognostic (3.67e-1)" "unprognostic (2.01e-1)" "unprognostic (2.33e-2)" "unprognostic (1.51e-2)" "potential prognostic unfavorable (2.75e-5)" "potential prognostic favorable (1.58e-4)" "unprognostic (1.54e-2)" "unprognostic (4.16e-1)" "unprognostic (2.65e-3)" "unprognostic (1.89e-3)" "potential prognostic unfavorable (3.76e-7)" "unprognostic (2.25e-2)" "unprognostic (9.55e-2)" "unprognostic (1.11e-1)" "unprognostic (6.09e-2)" "unprognostic (2.58e-1)" "unprognostic (2.26e-1)" "unprognostic (1.10e-2)" "unprognostic (9.08e-2)" "unprognostic (3.23e-1)" "unprognostic (7.77e-2)" "unprognostic (5.21e-2)" "unprognostic (5.89e-2)" "unprognostic (1.91e-1)" "unprognostic (1.07e-1)" "unprognostic (2.64e-1)" CBX6 ENSG00000183741 "Chromobox 6" O95503 22 38861422-38872249 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 81.0" "Cell type enhanced" "Detected in many" "Smooth muscle cells: 152.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048653, HPA075344" Uncertain Supported "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 62: Smooth muscle cells - Muscle contraction" 117 Nucleoplasm "Nuclear bodies" "HPA048653: , HPA075344: " "unprognostic (1.48e-1)" "unprognostic (4.52e-2)" "unprognostic (2.71e-1)" "unprognostic (1.06e-1)" "unprognostic (2.44e-1)" "unprognostic (3.58e-3)" "unprognostic (1.55e-1)" "unprognostic (4.66e-3)" "unprognostic (2.37e-1)" "unprognostic (3.24e-1)" "potential prognostic favorable (3.27e-4)" "unprognostic (2.65e-3)" "unprognostic (1.31e-2)" "unprognostic (1.08e-3)" "unprognostic (4.38e-3)" "unprognostic (1.51e-1)" "unprognostic (3.19e-1)" "unprognostic (5.88e-2)" "unprognostic (3.95e-2)" "unprognostic (4.15e-2)" "unprognostic (9.97e-2)" "potential prognostic favorable (1.26e-5)" "unprognostic (1.19e-1)" "unprognostic (1.98e-1)" "unprognostic (3.36e-2)" "unprognostic (1.27e-1)" "unprognostic (1.59e-1)" "unprognostic (7.93e-2)" "unprognostic (7.35e-2)" "unprognostic (2.98e-1)" "unprognostic (3.26e-2)" CBX7 ENSG00000100307 "Chromobox 7" O95931 22 39120167-39152680 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 85.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011574, HPA048677, HPA056480" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 62: Smooth muscle cells - Muscle contraction" 43 Nucleoplasm Cytosol "CAB011574: , HPA048677: , HPA056480: " "potential prognostic favorable (2.16e-5)" "unprognostic (5.13e-3)" "unprognostic (1.47e-1)" "unprognostic (1.38e-1)" "unprognostic (2.70e-2)" "unprognostic (2.81e-1)" "unprognostic (1.77e-1)" "unprognostic (1.40e-2)" "potential prognostic favorable (6.29e-4)" "unprognostic (3.14e-1)" "validated prognostic favorable (1.80e-7)" "validated prognostic favorable (2.01e-6)" "potential prognostic favorable (9.74e-6)" "unprognostic (1.92e-2)" "unprognostic (2.24e-2)" "unprognostic (2.47e-3)" "unprognostic (2.01e-2)" "unprognostic (4.64e-2)" "unprognostic (3.26e-1)" "unprognostic (4.34e-3)" "unprognostic (1.39e-1)" "potential prognostic favorable (5.23e-4)" "unprognostic (1.35e-1)" "unprognostic (8.97e-3)" "unprognostic (6.35e-2)" "unprognostic (7.98e-2)" "unprognostic (4.11e-2)" "unprognostic (3.22e-2)" "unprognostic (5.98e-2)" "unprognostic (3.46e-1)" "unprognostic (2.28e-1)" CBX8 "HPC3, PC3, RC1" ENSG00000141570 "Chromobox 8" Q9HC52 17 79792132-79801683 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 17.2;Endometrial ciliated cells: 16.0;Epididymal principal cells: 16.4;Fallopian tube ciliated cells: 19.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pituitary gland - Corticotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031462 Approved Enhanced Nucleoplasm NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 22: Epididymis - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 5: Rhabdoid - Unknown function" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 146 Nucleoplasm "HPA031462: " "unprognostic (8.46e-2)" "unprognostic (1.31e-1)" "potential prognostic favorable (4.35e-7)" "unprognostic (3.25e-3)" "unprognostic (2.65e-1)" "unprognostic (1.44e-2)" "unprognostic (6.41e-2)" "potential prognostic favorable (1.98e-5)" "unprognostic (1.62e-1)" "potential prognostic unfavorable (7.04e-4)" "potential prognostic unfavorable (6.24e-5)" "unprognostic (1.93e-2)" "unprognostic (1.74e-1)" "potential prognostic unfavorable (2.13e-8)" "unprognostic (2.73e-1)" "unprognostic (1.73e-1)" "unprognostic (2.83e-3)" "unprognostic (1.80e-1)" "unprognostic (1.20e-2)" "unprognostic (2.93e-1)" "unprognostic (3.91e-2)" "unprognostic (3.62e-3)" "unprognostic (1.20e-1)" "unprognostic (2.65e-1)" "unprognostic (1.30e-3)" "unprognostic (2.60e-2)" "unprognostic (1.23e-1)" "unprognostic (1.86e-2)" "unprognostic (9.28e-2)" "unprognostic (1.93e-1)" "unprognostic (1.02e-1)" CBY1 "C22orf2, Cby, Chibby, Chibby1, PGEA1, PIGEA-14, PIGEA14" ENSG00000100211 "Chibby family member 1, beta catenin antagonist" Q9Y3M2 22 38656636-38673854 "Predicted intracellular proteins" "Cilium biogenesis/degradation, Differentiation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fallopian tube ciliated cells: 131.9;Respiratory ciliated cells: 116.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020360 Supported Nucleoplasm,Nucleoli,Centrosome NA NA "Cluster 24: Non-specific - Transcription" "Cluster 75: Ovary - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 107: Ciliated cells - Cilia assembly & function" 42 Centrosome "Nucleoplasm, Nucleoli" "HPA020360: " "unprognostic (5.72e-2)" "unprognostic (2.44e-1)" "unprognostic (4.69e-2)" "unprognostic (5.07e-2)" "unprognostic (3.43e-1)" "unprognostic (9.91e-3)" "unprognostic (1.65e-1)" "unprognostic (2.38e-1)" "unprognostic (1.78e-1)" "unprognostic (4.84e-2)" "unprognostic (1.23e-1)" "unprognostic (2.36e-3)" "unprognostic (2.39e-2)" "unprognostic (1.09e-2)" "potential prognostic unfavorable (2.93e-4)" "unprognostic (2.25e-1)" "unprognostic (1.14e-1)" "unprognostic (3.48e-2)" "unprognostic (1.38e-2)" "unprognostic (2.63e-2)" "unprognostic (1.41e-1)" "unprognostic (3.11e-1)" "unprognostic (7.00e-2)" "unprognostic (3.81e-1)" "unprognostic (2.18e-1)" "unprognostic (1.15e-1)" "unprognostic (4.96e-2)" "unprognostic (7.93e-2)" "unprognostic (7.09e-2)" "unprognostic (5.83e-2)" "unprognostic (1.15e-2)" CBY2 "NURIT, SPERT" ENSG00000174015 "Chibby family member 2" Q8NA61 13 45702320-45714559 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 435 "testis: 93.0" "Group enriched" "Detected in some" 11 "Early spermatids: 983.4;Late spermatids: 2164.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder Urothelial Carcinoma (TCGA): 2.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Esophageal cancer: 1.1;head and neck cancer: 1.1" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA039359, HPA040046" Enhanced Approved "Calyx,Connecting piece,Mid piece,Principal piece,End piece,Annulus" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 59 "Calyx, Connecting piece, Mid piece, Principal piece, End piece, Annulus" "HPA039359: , HPA040046: " "unprognostic (9.25e-2)" "unprognostic (3.38e-1)" CBY3 ENSG00000204659 "Chibby family member 3" A6NI87 5 179678560-179681034 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 14 "testis: 12.3" "Cell type enhanced" "Detected in some" "Astrocytes: 1.9;Bergmann glia: 2.4;Brain excitatory neurons: 2.8;Brain inhibitory neurons: 3.0;Distal convoluted tubule cells: 1.2;Ependymal cells: 1.6;Loop of henle epithelial cells: 2.0;Microglia: 1.6;Oligodendrocyte progenitor cells: 1.9;Oligodendrocytes: 2.1;Other brain neurons: 2.8;Papillary tip epithelial cells: 3.1;Renal collecting duct intercalated cells: 1.1;Renal collecting duct principal cells: 3.1" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA069037 Uncertain Approved Nucleoplasm NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 6: Non-specific - Immune response" "Cluster 4: Non-specific - Transcription" "Cluster 98: Neurons - Neurotransmission & signaling" Nucleoplasm "HPA069037: " CC2D1A "Aki-1, FLJ20241, Freud-1, Lgd2, MRT3, TAPE" ENSG00000132024 "Coiled-coil and C2 domain containing 1A" Q6P1N0 19 13906201-13930879 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 46.1;Bergmann glia: 35.9;Brain excitatory neurons: 57.4;Brain inhibitory neurons: 51.5;Choroid plexus epithelial cells: 35.2;Distal convoluted tubule cells: 21.0;Ependymal cells: 30.2;Loop of henle epithelial cells: 26.2;Oligodendrocyte progenitor cells: 46.5;Oligodendrocytes: 36.4;Other brain neurons: 53.0;Papillary tip epithelial cells: 24.3;Proximal tubule cells: 21.6;Renal collecting duct intercalated cells: 25.6;Renal collecting duct principal cells: 26.1;Renal connecting tubule cells: 28.6;Tuft cells: 57.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005436, CAB015220" Supported Supported "Nucleoli fibrillar center,Plasma membrane,Basal body,Cytosol" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 102: Non-specific - Mixed function" 10 Cytosol "Nucleoli fibrillar center, Plasma membrane, Basal body" "CAB015220: , HPA005436: " "unprognostic (1.24e-1)" "unprognostic (3.01e-1)" "unprognostic (2.94e-1)" "unprognostic (1.14e-1)" "unprognostic (3.22e-1)" "unprognostic (2.04e-2)" "unprognostic (1.92e-1)" "unprognostic (1.35e-1)" "unprognostic (9.69e-3)" "unprognostic (1.19e-2)" "unprognostic (1.43e-1)" "unprognostic (5.94e-2)" "unprognostic (9.55e-2)" "unprognostic (2.66e-1)" "unprognostic (1.03e-1)" "unprognostic (3.34e-2)" "unprognostic (9.05e-2)" "unprognostic (7.32e-2)" "unprognostic (3.63e-1)" "unprognostic (4.83e-3)" "unprognostic (3.65e-1)" "unprognostic (2.51e-2)" "unprognostic (5.67e-2)" "unprognostic (1.53e-1)" "unprognostic (4.73e-2)" "unprognostic (1.75e-1)" "unprognostic (1.39e-1)" "unprognostic (4.93e-2)" "unprognostic (3.50e-1)" "unprognostic (5.61e-2)" "unprognostic (1.66e-1)" CC2D1B "Freud-2, KIAA1836, Lgd1" ENSG00000154222 "Coiled-coil and C2 domain containing 1B" Q5T0F9 1 52345723-52366205 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 10.3" "Lineage enriched" "Detected in all" 4 "granulocytes: 10.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027500, HPA031426" Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 37: Non-specific - mRNA processing" "Cluster 9: T-cells - Adaptive immunity: Regulation" 4 Nucleoplasm Vesicles "HPA027500: , HPA031426: " "unprognostic (2.30e-2)" "unprognostic (2.23e-1)" "unprognostic (1.60e-2)" "unprognostic (1.74e-2)" "potential prognostic favorable (5.75e-5)" "unprognostic (9.99e-2)" "unprognostic (9.04e-2)" "unprognostic (2.17e-1)" "unprognostic (1.84e-1)" "unprognostic (7.82e-3)" "unprognostic (1.15e-1)" "unprognostic (1.96e-1)" "unprognostic (1.69e-2)" "potential prognostic unfavorable (5.78e-7)" "unprognostic (4.45e-3)" "unprognostic (1.46e-1)" "unprognostic (4.39e-1)" "unprognostic (8.79e-2)" "unprognostic (1.30e-1)" "unprognostic (6.36e-2)" "unprognostic (2.51e-2)" "unprognostic (1.19e-1)" "unprognostic (3.06e-2)" "unprognostic (3.17e-1)" "unprognostic (1.64e-2)" "unprognostic (2.69e-1)" "unprognostic (1.94e-1)" "unprognostic (1.41e-1)" "unprognostic (1.16e-1)" "unprognostic (8.97e-2)" "unprognostic (3.54e-1)" CC2D2A "JBTS9, KIAA1345, MKS6" ENSG00000048342 "Coiled-coil and C2 domain containing 2A" Q9P2K1 4 15469865-15601552 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome, Meckel syndrome, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 78.4" "Cell type enhanced" "Detected in many" "Adipocytes: 228.5;Cone photoreceptor cells: 1678.9;Ependymal cells: 273.3;Epicardial cells: 268.3;Fallopian tube ciliated cells: 239.1;Respiratory ciliated cells: 344.1;Retinal bipolar cells: 221.8;Rod photoreceptor cells: 522.4" "Cell type enhanced" "Detected in all" "ependymal cell: 300.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Smooth muscle cells, Lung - Respiratory ciliated cells, Skeletal muscle - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044124 Approved Approved "Perinuclear theca,Connecting piece,Mid piece,Principal piece" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 79: Photoreceptor cells - Phototransduction" 9 "Connecting piece, Mid piece" "Perinuclear theca, Principal piece" "HPA044124: " "unprognostic (1.57e-2)" "unprognostic (5.70e-1)" "unprognostic (9.60e-2)" "unprognostic (5.50e-2)" "unprognostic (1.29e-1)" "unprognostic (3.87e-2)" "unprognostic (2.40e-1)" "unprognostic (5.57e-3)" "unprognostic (2.77e-2)" "unprognostic (1.84e-3)" "validated prognostic favorable (2.88e-6)" "validated prognostic favorable (1.32e-6)" "potential prognostic favorable (3.99e-9)" "unprognostic (1.68e-2)" "unprognostic (1.95e-1)" "unprognostic (2.76e-3)" "unprognostic (2.95e-1)" "unprognostic (6.99e-2)" "unprognostic (2.87e-2)" "unprognostic (2.24e-2)" "unprognostic (2.87e-1)" "unprognostic (2.70e-2)" "unprognostic (6.66e-2)" "unprognostic (9.81e-2)" "unprognostic (3.06e-1)" "unprognostic (1.13e-2)" "unprognostic (7.59e-2)" "potential prognostic unfavorable (3.78e-4)" "unprognostic (1.82e-1)" "unprognostic (6.81e-2)" "unprognostic (2.96e-3)" CC2D2B "bA248J23.4, bA690P14.3, C10orf130, C10orf131" ENSG00000188649 "Coiled-coil and C2 domain containing 2B" Q6DHV5 10 95907603-96033745 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 8.1" "Cell type enhanced" "Detected in many" "Adipocytes: 127.9;Astrocytes: 83.7;Cardiomyocytes: 261.9;Epicardial cells: 127.4;Late primary spermatocytes: 92.0;Microglia: 83.2;Myonuclei: 75.0;Neutrophil progenitors: 67.3;Neutrophils: 92.7" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 102.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA044091 Enhanced Approved "Nucleoplasm,Vesicles,Basal body,Cytosol" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 40: Non-specific - Mixed function" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 37: Neutrophil progenitors - Granulopoiesis" Nucleoplasm "Vesicles, Basal body, Cytosol" "HPA044091: " "unprognostic (1.20e-1)" "unprognostic (8.97e-3)" "unprognostic (3.43e-3)" "unprognostic (4.50e-2)" "unprognostic (2.30e-1)" "unprognostic (4.17e-2)" "unprognostic (1.86e-1)" "potential prognostic favorable (4.71e-5)" "unprognostic (3.56e-3)" "unprognostic (1.18e-1)" "unprognostic (1.66e-1)" "unprognostic (1.59e-1)" "unprognostic (6.08e-2)" "unprognostic (1.02e-1)" "unprognostic (2.71e-2)" "unprognostic (3.40e-1)" "unprognostic (6.69e-2)" "unprognostic (1.87e-1)" "unprognostic (3.07e-2)" "unprognostic (1.06e-1)" "unprognostic (2.05e-1)" "unprognostic (5.53e-2)" "unprognostic (3.47e-2)" CCAR1 "CARP-1, CARP1, FLJ10590" ENSG00000060339 "Cell division cycle and apoptosis regulator 1" Q8IX12 10 68721012-68792377 "Cancer-related genes, Essential proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, Transcription, Transcription regulation" "Activator, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007856, HPA048513" Supported Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 49: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 52: Non-specific - Mitochondria" "Cluster 17: Non-specific - RNA processing" 44 Nucleoplasm "Golgi apparatus" "HPA007856: , HPA048513: " "unprognostic (7.48e-2)" "unprognostic (2.57e-2)" "unprognostic (3.10e-1)" "unprognostic (8.06e-2)" "unprognostic (3.44e-2)" "unprognostic (1.08e-1)" "unprognostic (2.20e-2)" "potential prognostic favorable (4.12e-4)" "unprognostic (1.65e-1)" "unprognostic (2.64e-3)" "unprognostic (1.31e-1)" "unprognostic (1.43e-1)" "unprognostic (1.06e-1)" "potential prognostic unfavorable (3.87e-6)" "unprognostic (4.58e-2)" "unprognostic (8.35e-3)" "unprognostic (6.79e-2)" "unprognostic (1.63e-1)" "unprognostic (9.97e-2)" "unprognostic (1.11e-1)" "unprognostic (1.56e-1)" "unprognostic (3.00e-2)" "potential prognostic unfavorable (3.95e-4)" "potential prognostic unfavorable (3.86e-4)" "unprognostic (1.68e-1)" "unprognostic (5.61e-1)" "unprognostic (6.43e-2)" "unprognostic (3.97e-1)" "unprognostic (1.79e-1)" "unprognostic (1.66e-1)" "unprognostic (2.46e-2)" CCAR2 "DBC-1, DBC1, KIAA1967, NET35" ENSG00000158941 "Cell cycle and apoptosis regulator 2" Q8N163 8 22604757-22620964 "Predicted intracellular proteins" "Apoptosis, Biological rhythms, Cell cycle, DNA damage, mRNA processing, mRNA splicing, Transcription, Transcription regulation, Wnt signaling pathway" "Activator, Metalloenzyme inhibitor, Repressor" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epicardial cells: 77.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019907, HPA019943, CAB072827, CAB072828" Enhanced Enhanced "Nucleoplasm,Nuclear bodies" NA NA 17000 "Cluster 33: Non-specific - ATP binding" "Cluster 15: Bone marrow - Innate immune response" "Cluster 53: Neurons - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 51: Secretory epithelial cells - Mixed function" 57 "Nucleoplasm, Nuclear bodies" "CAB072827: , CAB072828: , HPA019907: , HPA019943: " "unprognostic (1.80e-2)" "unprognostic (8.45e-2)" "unprognostic (4.39e-2)" "unprognostic (3.47e-3)" "unprognostic (6.67e-2)" "unprognostic (2.23e-1)" "unprognostic (3.93e-3)" "unprognostic (1.17e-2)" "potential prognostic unfavorable (2.12e-4)" "potential prognostic favorable (6.80e-7)" "unprognostic (3.29e-3)" "unprognostic (1.53e-1)" "unprognostic (1.40e-2)" "unprognostic (2.88e-1)" "unprognostic (3.76e-2)" "unprognostic (2.26e-1)" "unprognostic (1.15e-2)" "unprognostic (6.56e-2)" "unprognostic (5.78e-2)" "unprognostic (1.79e-1)" "unprognostic (4.15e-2)" "unprognostic (3.95e-1)" "unprognostic (1.29e-2)" "unprognostic (6.19e-3)" "unprognostic (2.23e-1)" "unprognostic (4.46e-2)" "unprognostic (1.67e-1)" "unprognostic (1.17e-1)" "unprognostic (3.75e-2)" CCBE1 "FLJ30681, KIAA1983" ENSG00000183287 "Collagen and calcium binding EGF domains 1" Q6UXH8 18 59430939-59697662 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" Angiogenesis "Developmental protein" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 25.6" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 959.8;Epididymal efferent duct ciliated cells: 154.0;Fallopian tube ciliated cells: 218.1;Fibro-adipogenic progenitors: 151.3;Granulosa cells: 206.0;Hepatic stellate cells: 245.3;Mesothelial cells: 412.7;Ovarian stromal cells: 322.3;Podocytes: 1052.3;Renal collecting duct intercalated cells: 165.7" "Cell type enhanced" "Detected in many" "hippocampal CA1-3: 458.6" "Cancer enriched" "Detected in many" 5 "Kidney Chromophobe (TCGA): 12.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "basophil: 8.9" "Lineage enriched" "Detected in single" 19 "granulocytes: 8.9" "Group enriched" "Detected in many" 4 "Adrenocortical cancer: 56.8;thyroid cancer: 19.4" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal cortex cells, Liver - Hepatic stellate cells, Lung - Fibroblasts_1, Prostate - Smooth muscle cells, Skin - Fibroblasts_2, Stomach - Parietal cells" "Group enriched" "Detected in many" 5 "cerebral cortex: 2.7;hippocampal formation: 8.7" "Low region specificity" "Detected in all" "HPA041361, HPA041374" Uncertain Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 75: Ovary - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 18: Adrenal cortex cells - Steroidogensis" 3 "Plasma membrane, Cytosol" "HPA041361: , HPA041374: " "unprognostic (4.22e-1)" "unprognostic (5.26e-2)" "unprognostic (1.87e-2)" "unprognostic (2.44e-1)" "potential prognostic unfavorable (2.27e-4)" "unprognostic (4.90e-2)" "potential prognostic unfavorable (2.17e-4)" "unprognostic (6.44e-3)" "unprognostic (5.58e-2)" "unprognostic (1.88e-1)" "unprognostic (1.90e-1)" "unprognostic (1.30e-2)" "unprognostic (2.75e-1)" "unprognostic (2.28e-2)" "unprognostic (2.62e-1)" "unprognostic (1.05e-2)" "unprognostic (3.94e-3)" "unprognostic (1.12e-1)" "unprognostic (1.27e-1)" CCDC102A MGC10992 ENSG00000135736 "Coiled-coil domain containing 102A" Q96A19 16 57512181-57536571 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 25.8;Peritubular myoid cells: 32.6;Respiratory ciliated cells: 25.1;Smooth muscle cells: 27.2" "Cell type enhanced" "Detected in some" "ependymal cell: 9.0;leukocyte: 8.8;pericyte: 8.8;vascular associated smooth muscle cell: 11.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA040598, HPA040958" Supported Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 62: Smooth muscle cells - Muscle contraction" 2 Nucleoplasm "Nuclear bodies" "HPA040598: , HPA040958: " "unprognostic (1.61e-1)" "unprognostic (5.18e-2)" "unprognostic (2.65e-1)" "unprognostic (2.23e-2)" "unprognostic (5.58e-2)" "unprognostic (3.92e-2)" "unprognostic (1.56e-1)" "unprognostic (1.72e-1)" "unprognostic (3.20e-1)" "potential prognostic favorable (8.21e-4)" "unprognostic (1.44e-2)" "unprognostic (2.68e-1)" "unprognostic (4.00e-3)" "unprognostic (3.87e-1)" "unprognostic (1.25e-1)" "unprognostic (6.32e-2)" "unprognostic (2.23e-1)" "unprognostic (1.82e-3)" "unprognostic (3.49e-3)" "unprognostic (4.50e-2)" "unprognostic (2.24e-1)" "unprognostic (1.43e-1)" "unprognostic (7.59e-2)" "unprognostic (2.72e-2)" "unprognostic (6.17e-2)" "unprognostic (2.15e-2)" "unprognostic (2.12e-1)" "unprognostic (2.41e-1)" "unprognostic (1.70e-1)" "unprognostic (9.59e-2)" "unprognostic (3.06e-2)" CCDC102B "ACY1L, AN, C18orf14, FLJ23594, HsT1731" ENSG00000150636 "Coiled-coil domain containing 102B" Q68D86 18 68715209-69055189 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 26.6" "Cell type enhanced" "Detected in many" "Early spermatids: 131.8;Fibro-adipogenic progenitors: 191.9;Fibroblasts: 101.1;Late spermatids: 102.6;Leydig cells: 97.7;Lymphatic endothelial cells: 127.3;Pericytes: 446.1" "Cell type enhanced" "Detected in all" "pericyte: 370.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "plasmacytoid DC: 9.1" "Lineage enriched" "Detected in many" 5 "dendritic cells: 9.1" "Cancer enhanced" "Detected in many" "Rhabdoid: 12.8" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Stomach - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Fibroblasts" "HPA040623, HPA048194" Approved NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 9: Non-specific - Receptor signaling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 110: Mural cells - ECM organization" 93 "HPA040623: , HPA048194: " "unprognostic (1.90e-1)" "unprognostic (3.38e-3)" "unprognostic (4.30e-2)" "unprognostic (5.06e-2)" "unprognostic (1.86e-2)" "unprognostic (2.69e-1)" "unprognostic (1.10e-1)" "unprognostic (1.49e-1)" "unprognostic (2.97e-1)" "unprognostic (1.99e-1)" "unprognostic (5.40e-3)" "unprognostic (1.50e-3)" "unprognostic (1.13e-2)" "unprognostic (1.03e-2)" "unprognostic (2.06e-1)" "unprognostic (4.46e-2)" "unprognostic (7.43e-3)" "unprognostic (5.42e-3)" "unprognostic (1.57e-3)" "unprognostic (5.10e-3)" "unprognostic (2.75e-3)" "unprognostic (2.37e-1)" "potential prognostic unfavorable (1.48e-4)" "unprognostic (1.17e-1)" "unprognostic (3.40e-2)" "unprognostic (2.09e-1)" "unprognostic (3.67e-3)" "unprognostic (2.00e-1)" "unprognostic (9.64e-2)" CCDC103 "CILD17, FLJ13094, FLJ34211, PR46b" ENSG00000167131 "Coiled-coil domain containing 103" Q8IW40 17 44899142-44905390 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "fallopian tube: 23.1;testis: 38.9" "Cell type enhanced" "Detected in some" "Adipocytes: 2.5;Cardiomyocytes: 7.4;Choroid plexus epithelial cells: 3.1;Ependymal cells: 16.4;Epicardial cells: 18.2;Late primary spermatocytes: 2.3;Late spermatids: 4.2;Other brain neurons: 2.3" "Cell type enriched" "Detected in many" 6 "ependymal cell: 27.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" HPA043131 Approved "Cytosol,Connecting piece,Mid piece" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" 19 "Cytosol, Connecting piece, Mid piece" "HPA043131: " "unprognostic (5.99e-3)" "unprognostic (5.17e-2)" "unprognostic (1.49e-1)" "unprognostic (5.66e-2)" "unprognostic (1.90e-1)" "unprognostic (7.70e-2)" "unprognostic (3.18e-2)" "potential prognostic favorable (1.09e-6)" "unprognostic (3.02e-2)" "unprognostic (1.78e-1)" "unprognostic (4.04e-1)" "unprognostic (2.22e-2)" "unprognostic (3.67e-2)" "unprognostic (1.75e-1)" "unprognostic (3.47e-1)" "unprognostic (2.67e-1)" "potential prognostic unfavorable (9.42e-4)" "unprognostic (1.35e-1)" "unprognostic (4.37e-3)" "unprognostic (2.85e-2)" "unprognostic (3.64e-1)" "unprognostic (1.91e-1)" "unprognostic (1.94e-1)" "unprognostic (5.02e-2)" CCDC105 FLJ40365 ENSG00000160994 "Coiled-coil domain containing 105" Q8IYK2 19 15010726-15023276 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 69 "testis: 14.3" "Group enriched" "Detected in some" 5 "Early spermatids: 184.6;Late primary spermatocytes: 158.8" "Cell type enhanced" "Detected in some" "hippocampal CA4: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA058585 Approved NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 47: Leukemia - Hemostasis" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 2 "HPA058585: " CCDC106 HSU79303 ENSG00000173581 "Coiled-coil domain containing 106" Q9BWC9 19 55641062-55653161 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 68.7" "Cell type enhanced" "Detected in many" "Oocytes: 50.7;Undifferentiated spermatogonia: 44.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 9.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Spleen - B-cells (Spleen), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041925, HPA043219" Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 23 Nucleoplasm Cytosol "HPA041925: , HPA043219: " "unprognostic (3.71e-2)" "unprognostic (1.10e-2)" "unprognostic (3.63e-1)" "unprognostic (3.83e-2)" "unprognostic (2.38e-1)" "unprognostic (3.10e-2)" "unprognostic (4.05e-2)" "unprognostic (2.28e-3)" "unprognostic (1.64e-1)" "unprognostic (1.27e-1)" "potential prognostic favorable (8.84e-9)" "unprognostic (7.90e-2)" "potential prognostic favorable (2.62e-5)" "unprognostic (1.01e-1)" "unprognostic (1.15e-1)" "unprognostic (1.22e-1)" "unprognostic (2.36e-1)" "unprognostic (3.64e-2)" "unprognostic (3.57e-2)" "unprognostic (1.85e-1)" "unprognostic (7.34e-2)" "potential prognostic favorable (1.08e-4)" "unprognostic (1.15e-1)" "unprognostic (1.96e-1)" "unprognostic (5.50e-2)" "unprognostic (1.61e-2)" "unprognostic (9.24e-2)" "unprognostic (1.84e-1)" "unprognostic (3.62e-2)" "unprognostic (3.64e-2)" "unprognostic (8.38e-2)" CCDC107 MGC31967 ENSG00000159884 "Coiled-coil domain containing 107" Q8WV48 9 35658290-35661511 "Essential proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Smooth muscle cells: 261.1;Vascular smooth muscle cells: 311.4" "Cell type enhanced" "Detected in all" "vascular associated smooth muscle cell: 129.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Minor Salivary Gland - Minor salivary glandular cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016857, HPA050442" Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 25: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 62: Smooth muscle cells - Muscle contraction" 30 "Plasma membrane, Cell Junctions" Nucleoplasm "HPA016857: , HPA050442: " "unprognostic (1.21e-2)" "unprognostic (3.50e-2)" "unprognostic (2.79e-1)" "unprognostic (3.79e-1)" "unprognostic (5.09e-2)" "unprognostic (1.71e-3)" "unprognostic (7.36e-2)" "unprognostic (2.22e-1)" "unprognostic (5.26e-2)" "unprognostic (7.23e-2)" "unprognostic (2.57e-1)" "unprognostic (1.06e-1)" "unprognostic (3.47e-2)" "unprognostic (1.10e-1)" "unprognostic (1.83e-1)" "unprognostic (1.40e-1)" "unprognostic (1.75e-2)" "unprognostic (1.15e-2)" "unprognostic (1.26e-1)" "unprognostic (9.07e-2)" "unprognostic (2.74e-2)" "unprognostic (9.45e-3)" "unprognostic (2.87e-2)" "unprognostic (4.75e-2)" "potential prognostic unfavorable (8.83e-4)" "unprognostic (3.38e-2)" "unprognostic (1.99e-1)" "unprognostic (4.51e-1)" "unprognostic (1.80e-1)" "unprognostic (1.65e-1)" "unprognostic (2.69e-2)" CCDC110 "CT52, KM-HN-1, MGC33607" ENSG00000168491 "Coiled-coil domain containing 110" Q8TBZ0 4 185445182-185471752 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "pancreas: 29.0;testis: 93.5" "Group enriched" "Detected in many" 6 "Early spermatids: 584.9;Late primary spermatocytes: 1619.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 11.9" "Adipose subcutaneous - Smooth muscle cells, Minor Salivary Gland - Minor salivary glandular cells, Stomach - Chief cells, Testis - Early spermatids" HPA071931 Supported Nucleoplasm,Cytosol NA NA "Cluster 21: Testis - Mixed function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 1 Nucleoplasm Cytosol "HPA071931: " "unprognostic (1.62e-1)" "unprognostic (8.97e-2)" "unprognostic (2.66e-1)" "unprognostic (9.29e-3)" "unprognostic (1.61e-1)" "potential prognostic favorable (3.79e-7)" "unprognostic (3.38e-2)" "unprognostic (2.29e-3)" "unprognostic (5.38e-2)" "unprognostic (1.45e-1)" "unprognostic (1.74e-1)" "unprognostic (1.32e-1)" "unprognostic (9.66e-2)" "unprognostic (1.51e-1)" "unprognostic (2.40e-1)" "unprognostic (7.07e-2)" "unprognostic (1.50e-1)" "unprognostic (2.07e-3)" CCDC112 MGC39633 ENSG00000164221 "Coiled-coil domain containing 112" Q8NEF3 5 115267190-115296693 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 38.0" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 140.7;Late primary spermatocytes: 324.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045120, HPA050621" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" "No annotated function" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 57: Testis - Spermatogenesis" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 11 "Plasma membrane, Cytosol" Nucleoplasm "HPA045120: , HPA050621: " "unprognostic (2.29e-1)" "unprognostic (2.24e-3)" "unprognostic (9.27e-3)" "unprognostic (1.46e-1)" "unprognostic (2.56e-1)" "unprognostic (1.25e-1)" "unprognostic (1.69e-1)" "unprognostic (2.79e-1)" "unprognostic (2.30e-1)" "unprognostic (6.87e-2)" "potential prognostic favorable (5.21e-4)" "unprognostic (2.33e-1)" "unprognostic (6.96e-3)" "potential prognostic unfavorable (1.76e-5)" "unprognostic (3.72e-1)" "unprognostic (3.71e-1)" "unprognostic (1.24e-1)" "unprognostic (7.39e-2)" "unprognostic (1.40e-1)" "unprognostic (1.71e-1)" "unprognostic (4.59e-3)" "unprognostic (6.42e-2)" "unprognostic (1.71e-2)" "unprognostic (3.17e-1)" "unprognostic (1.58e-2)" "unprognostic (5.36e-2)" "unprognostic (1.85e-1)" "unprognostic (2.53e-1)" "unprognostic (1.36e-1)" "unprognostic (2.03e-3)" "unprognostic (3.25e-1)" CCDC113 "DKFZp434N1418, HSPC065" ENSG00000103021 "Coiled-coil domain containing 113" Q9H0I3 16 58231157-58283836 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 29.4" "Group enriched" "Detected in many" 6 "Early spermatids: 222.0;Endometrial ciliated cells: 172.8;Ependymal cells: 103.7;Epididymal efferent duct ciliated cells: 127.6;Fallopian tube ciliated cells: 334.7;Late primary spermatocytes: 123.7;Late spermatids: 229.6;Respiratory ciliated cells: 373.7" "Cell type enriched" "Detected in many" 4 "ependymal cell: 133.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 10 "basophil: 6.5" "Lineage enriched" "Detected in single" 37 "granulocytes: 6.5" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA040759, HPA040869" Uncertain NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 107: Ciliated cells - Cilia assembly & function" 2 "HPA040759: , HPA040869: " "unprognostic (2.09e-2)" "unprognostic (1.77e-2)" "unprognostic (8.63e-2)" "unprognostic (6.10e-2)" "unprognostic (2.44e-3)" "unprognostic (1.39e-2)" "unprognostic (3.77e-1)" "unprognostic (4.35e-2)" "potential prognostic unfavorable (3.05e-4)" "unprognostic (3.97e-2)" "unprognostic (4.87e-3)" "unprognostic (7.12e-2)" "unprognostic (2.44e-1)" "unprognostic (1.55e-1)" "unprognostic (1.80e-2)" "potential prognostic unfavorable (9.94e-5)" "unprognostic (1.37e-1)" "unprognostic (1.16e-1)" "unprognostic (3.38e-1)" "unprognostic (1.36e-1)" "unprognostic (1.84e-1)" "unprognostic (9.64e-2)" "potential prognostic favorable (5.88e-5)" "unprognostic (7.53e-2)" "unprognostic (7.13e-2)" "unprognostic (2.21e-2)" "unprognostic (1.40e-1)" "unprognostic (1.43e-3)" "unprognostic (3.32e-2)" CCDC115 "ccp1, FLJ30131, MGC12981" ENSG00000136710 "Coiled-coil domain containing 115" Q96NT0 2 130337933-130342699 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 239.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034598 Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 15: Non-specific - Protein processing" 19 "Plasma membrane" Vesicles "HPA034598: " "unprognostic (1.47e-2)" "unprognostic (8.39e-2)" "unprognostic (2.39e-2)" "unprognostic (1.45e-1)" "unprognostic (2.20e-2)" "unprognostic (7.67e-2)" "unprognostic (4.66e-1)" "unprognostic (1.18e-1)" "unprognostic (7.55e-2)" "unprognostic (3.36e-2)" "potential prognostic favorable (5.60e-8)" "unprognostic (1.01e-2)" "unprognostic (6.54e-2)" "unprognostic (7.12e-2)" "unprognostic (2.71e-2)" "unprognostic (1.47e-1)" "unprognostic (8.60e-2)" "unprognostic (1.31e-2)" "unprognostic (2.83e-1)" "unprognostic (8.29e-2)" "unprognostic (1.56e-1)" "unprognostic (1.52e-1)" "unprognostic (2.49e-1)" "unprognostic (4.82e-1)" "unprognostic (1.18e-1)" "unprognostic (6.76e-2)" "unprognostic (1.22e-1)" "unprognostic (4.20e-2)" "unprognostic (1.34e-1)" "unprognostic (2.51e-1)" "unprognostic (4.59e-2)" CCDC116 FLJ36046 ENSG00000161180 "Coiled-coil domain containing 116" Q8IYX3 22 21632716-21637329 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 22 "testis: 28.5" "Group enriched" "Detected in some" 76 "Early spermatids: 257.1;Late primary spermatocytes: 116.7;Late spermatids: 269.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 47: Leukemia - Hemostasis" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 24 "unprognostic (1.58e-1)" CCDC117 FLJ33814 ENSG00000159873 "Coiled-coil domain containing 117" Q8IWD4 22 28772674-28789301 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 84.8;Late primary spermatocytes: 86.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000826 Uncertain Approved Nucleoplasm,Microtubules,Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 66: Non-specific - Mitochondria" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" 14 Nucleoplasm "Microtubules, Cytosol" "HPA000826: " "unprognostic (1.37e-1)" "unprognostic (7.05e-2)" "unprognostic (1.80e-1)" "unprognostic (1.01e-1)" "unprognostic (1.80e-1)" "unprognostic (1.37e-3)" "unprognostic (2.22e-1)" "unprognostic (1.43e-1)" "unprognostic (2.19e-1)" "unprognostic (1.50e-1)" "unprognostic (2.63e-3)" "unprognostic (2.78e-2)" "unprognostic (1.57e-2)" "unprognostic (1.29e-1)" "unprognostic (5.46e-2)" "unprognostic (4.48e-3)" "unprognostic (9.18e-2)" "unprognostic (2.57e-2)" "potential prognostic favorable (5.04e-4)" "unprognostic (2.53e-2)" "unprognostic (3.48e-3)" "unprognostic (1.85e-1)" "unprognostic (9.01e-2)" "unprognostic (1.56e-1)" "unprognostic (2.13e-3)" "unprognostic (1.02e-1)" "unprognostic (2.45e-2)" "unprognostic (1.84e-1)" "unprognostic (3.08e-1)" "potential prognostic unfavorable (1.49e-4)" "unprognostic (2.40e-1)" CCDC12 MGC23918 ENSG00000160799 "Coiled-coil domain containing 12" Q8WUD4 3 46921726-46982010 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 480.7;Esophageal suprabasal cells: 427.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056814, HPA060530" Approved Supported Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 35: RS4;11 - Unknown function" "Cluster 65: Non-specific - Cell growth & division" 57 Nucleoplasm "HPA056814: , HPA060530: " "unprognostic (2.06e-1)" "unprognostic (2.21e-3)" "unprognostic (7.31e-2)" "unprognostic (5.22e-2)" "unprognostic (2.25e-1)" "unprognostic (1.96e-2)" "unprognostic (2.35e-2)" "unprognostic (1.01e-2)" "unprognostic (4.91e-2)" "unprognostic (5.33e-3)" "unprognostic (2.35e-1)" "unprognostic (2.43e-1)" "potential prognostic favorable (3.12e-6)" "unprognostic (4.07e-2)" "unprognostic (2.12e-2)" "unprognostic (9.59e-2)" "unprognostic (8.37e-2)" "unprognostic (1.04e-1)" "unprognostic (1.36e-1)" "unprognostic (2.41e-1)" "unprognostic (2.52e-1)" "unprognostic (5.25e-2)" "unprognostic (2.02e-1)" "unprognostic (7.66e-2)" "unprognostic (1.77e-1)" "unprognostic (1.88e-1)" "unprognostic (6.39e-2)" "unprognostic (3.23e-1)" "unprognostic (3.31e-2)" "unprognostic (1.53e-1)" "unprognostic (6.02e-2)" CCDC120 JM11 ENSG00000147144 "Coiled-coil domain containing 120" Q96HB5 X 49053572-49069857 "Cancer-related genes, Predicted intracellular proteins" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 34.6;skin 1: 28.0" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 114.9;Esophageal suprabasal cells: 53.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Skin - Keratinocyte (granular), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000561 Uncertain Mitochondria NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 15: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 119 Mitochondria "HPA000561: " "unprognostic (6.80e-3)" "unprognostic (9.84e-3)" "unprognostic (1.56e-1)" "unprognostic (7.19e-3)" "unprognostic (1.38e-1)" "unprognostic (1.36e-1)" "unprognostic (1.68e-3)" "unprognostic (2.93e-3)" "unprognostic (1.16e-2)" "unprognostic (2.56e-1)" "unprognostic (2.22e-2)" "unprognostic (3.14e-1)" "unprognostic (7.88e-2)" "unprognostic (2.77e-3)" "unprognostic (7.57e-3)" "unprognostic (1.98e-1)" "unprognostic (3.21e-1)" "unprognostic (2.98e-1)" "unprognostic (1.13e-2)" "unprognostic (2.03e-1)" "unprognostic (2.18e-1)" "unprognostic (1.08e-1)" "unprognostic (6.02e-2)" "unprognostic (1.54e-1)" "unprognostic (1.17e-1)" "unprognostic (6.38e-3)" "unprognostic (2.45e-2)" "unprognostic (2.96e-2)" "unprognostic (1.60e-1)" "unprognostic (6.93e-2)" "unprognostic (2.41e-2)" CCDC121 "FLJ13646, FLJ43364" ENSG00000176714 "Coiled-coil domain containing 121" Q6ZUS5 2 27625638-27629012 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 23.7" "Cell type enhanced" "Detected in many" "Early spermatids: 245.5;Fallopian tube ciliated cells: 28.3;Late primary spermatocytes: 92.9;Late spermatids: 45.6;Respiratory ciliated cells: 27.4" "Cell type enhanced" "Detected in many" "ependymal cell: 18.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 10.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" HPA051791 Uncertain Approved "Actin filaments,Cytosol" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 4 "Actin filaments, Cytosol" "HPA051791: " "unprognostic (3.99e-2)" "unprognostic (1.86e-2)" "unprognostic (1.20e-1)" "unprognostic (7.28e-2)" "unprognostic (2.05e-1)" "unprognostic (1.46e-2)" "unprognostic (2.41e-1)" "unprognostic (1.17e-1)" "unprognostic (4.78e-2)" "unprognostic (1.65e-1)" "potential prognostic favorable (1.60e-10)" "unprognostic (4.22e-3)" "unprognostic (2.00e-1)" "unprognostic (7.48e-3)" "unprognostic (3.79e-2)" "unprognostic (1.37e-1)" "unprognostic (1.98e-1)" "unprognostic (2.09e-2)" "unprognostic (5.47e-2)" "unprognostic (1.26e-1)" "unprognostic (2.92e-1)" "unprognostic (2.04e-2)" "unprognostic (3.10e-2)" "unprognostic (7.48e-2)" "unprognostic (7.95e-3)" "unprognostic (3.99e-1)" "unprognostic (7.33e-2)" "unprognostic (7.39e-2)" "unprognostic (2.35e-1)" "unprognostic (1.38e-1)" "unprognostic (2.24e-1)" CCDC122 FLJ31846 ENSG00000151773 "Coiled-coil domain containing 122" Q5T0U0 13 43823909-43879740 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 129.1;Sertoli cells: 114.0" "Cell type enhanced" "Detected in many" "oligodendrocyte: 168.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034233, HPA054995, HPA061456" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 32: Basophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 19: Non-specific - Unknown function" "Cluster 80: Oligodendrocytes - Myelination" Vesicles Nucleoplasm "CAB034233: , HPA054995: , HPA061456: " "unprognostic (1.09e-1)" "unprognostic (1.60e-1)" "unprognostic (5.81e-2)" "unprognostic (2.94e-2)" "unprognostic (1.98e-1)" "unprognostic (4.06e-2)" "unprognostic (3.84e-3)" "unprognostic (5.47e-3)" "unprognostic (1.80e-2)" "unprognostic (7.14e-2)" "unprognostic (8.90e-3)" "unprognostic (1.25e-1)" "potential prognostic favorable (8.55e-6)" "unprognostic (2.28e-1)" "unprognostic (1.08e-1)" "unprognostic (2.08e-1)" "unprognostic (1.35e-2)" "unprognostic (1.20e-1)" "unprognostic (7.64e-2)" "unprognostic (1.97e-3)" "unprognostic (8.72e-3)" "unprognostic (2.38e-3)" "unprognostic (1.98e-2)" "unprognostic (6.26e-2)" "unprognostic (1.30e-1)" "unprognostic (2.95e-3)" "unprognostic (1.45e-2)" "unprognostic (5.90e-2)" "unprognostic (1.08e-1)" "unprognostic (1.59e-1)" "unprognostic (1.83e-1)" CCDC124 "Lso2, oxs1" ENSG00000007080 "Coiled-coil domain containing 124" Q96CT7 19 17933015-17943991 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 298.9;Esophageal suprabasal cells: 181.9;Late spermatids: 181.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041708, HPA046765" Supported Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 23: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 35 "Plasma membrane, Cytosol" "HPA041708: , HPA046765: " "unprognostic (1.86e-1)" "unprognostic (1.03e-1)" "unprognostic (2.71e-1)" "unprognostic (4.33e-1)" "unprognostic (2.93e-2)" "unprognostic (4.95e-2)" "unprognostic (3.55e-1)" "unprognostic (1.67e-1)" "unprognostic (1.12e-1)" "unprognostic (1.31e-2)" "unprognostic (3.43e-1)" "unprognostic (3.93e-1)" "unprognostic (1.93e-1)" "potential prognostic unfavorable (3.84e-6)" "unprognostic (1.40e-3)" "unprognostic (3.89e-2)" "unprognostic (1.55e-1)" "unprognostic (2.20e-3)" "unprognostic (1.11e-1)" "unprognostic (2.59e-1)" "unprognostic (1.10e-1)" "unprognostic (4.25e-2)" "unprognostic (1.79e-2)" "unprognostic (9.26e-3)" "unprognostic (7.81e-2)" "unprognostic (5.86e-3)" "unprognostic (3.21e-1)" "unprognostic (2.63e-1)" "unprognostic (5.70e-2)" "unprognostic (1.71e-1)" "unprognostic (5.61e-2)" CCDC125 KENAE ENSG00000183323 "Coiled-coil domain containing 125" Q86Z20 5 69280175-69332809 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 60.8;Distal convoluted tubule cells: 66.8;Ependymal cells: 54.6;Loop of henle epithelial cells: 56.3;Microglia: 63.0;Neutrophil progenitors: 73.5;Papillary tip epithelial cells: 58.0;Proximal tubule cells: 54.4;Renal collecting duct principal cells: 50.7;Renal connecting tubule cells: 59.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 15.0;neutrophil: 11.3" "Lineage enriched" "Detected in all" 5 "granulocytes: 15.0" "Low cancer specificity" "Detected in many" "Prostate - Prostate glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA041878 Approved Uncertain "Nucleoplasm,Nuclear membrane,Intermediate filaments" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 53 "Nuclear membrane, Intermediate filaments" Nucleoplasm "HPA041878: " "unprognostic (2.96e-3)" "unprognostic (1.53e-2)" "unprognostic (2.54e-1)" "unprognostic (2.58e-2)" "unprognostic (2.21e-3)" "unprognostic (8.30e-2)" "unprognostic (5.49e-3)" "unprognostic (3.23e-2)" "unprognostic (9.07e-2)" "unprognostic (1.04e-3)" "unprognostic (3.36e-2)" "unprognostic (3.99e-2)" "unprognostic (9.51e-3)" "unprognostic (3.43e-1)" "unprognostic (8.31e-3)" "unprognostic (7.53e-2)" "unprognostic (3.52e-2)" "unprognostic (1.71e-2)" "unprognostic (2.59e-1)" "unprognostic (1.53e-1)" "unprognostic (2.68e-1)" "unprognostic (3.20e-3)" "unprognostic (1.14e-1)" "unprognostic (4.77e-3)" "unprognostic (3.12e-3)" "unprognostic (8.24e-2)" "unprognostic (1.19e-1)" "unprognostic (4.21e-2)" "unprognostic (2.54e-1)" "unprognostic (7.19e-3)" "unprognostic (1.65e-2)" CCDC126 FLJ23031 ENSG00000169193 "Coiled-coil domain containing 126" Q96EE4 7 23597382-23644708 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 32.5" "Group enriched" "Detected in many" 4 "Early spermatids: 783.0;Late primary spermatocytes: 254.4;Late spermatids: 762.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 6 "basophil: 480.6" "Lineage enriched" "Detected in all" 23 "granulocytes: 480.6" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010969, HPA026883" Uncertain Approved "Golgi apparatus" "Secreted to blood" "No annotated function" NA NA 10000000 "Cluster 46: Basophils - Proteolysis" "Cluster 6: Testis - Spermatogenesis" "Cluster 25: Non-specific - Transcription" "Cluster 67: Non-specific - Unknown function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 1 "Golgi apparatus" "HPA010969: , HPA026883: " "unprognostic (1.09e-2)" "unprognostic (6.74e-2)" "unprognostic (1.80e-1)" "unprognostic (1.32e-1)" "unprognostic (5.53e-2)" "unprognostic (1.92e-2)" "unprognostic (3.37e-2)" "unprognostic (6.88e-2)" "unprognostic (7.34e-2)" "unprognostic (6.97e-2)" "potential prognostic favorable (3.57e-5)" "unprognostic (3.10e-3)" "unprognostic (7.30e-2)" "unprognostic (9.22e-2)" "unprognostic (3.43e-2)" "unprognostic (3.29e-1)" "unprognostic (7.42e-2)" "unprognostic (1.07e-1)" "unprognostic (1.71e-1)" "unprognostic (3.59e-2)" "potential prognostic unfavorable (3.25e-4)" "unprognostic (5.08e-2)" "unprognostic (2.72e-1)" "unprognostic (2.91e-1)" "unprognostic (1.13e-1)" "unprognostic (3.50e-2)" "unprognostic (1.48e-1)" "unprognostic (1.34e-1)" "unprognostic (1.14e-1)" "unprognostic (3.55e-2)" "unprognostic (4.32e-1)" CCDC127 FLJ25701 ENSG00000164366 "Coiled-coil domain containing 127" Q96BQ5 5 196868-218153 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 93.7;Late primary spermatocytes: 54.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045052 Approved Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 24: Neurons - Mixed function" "Cluster 29: Non-specific - Unknown function" "Cluster 84: Apical squamous epithelium - Cornification" 5 "Nucleoplasm, Nucleoli fibrillar center" "HPA045052: " "unprognostic (3.12e-1)" "unprognostic (2.48e-3)" "unprognostic (3.55e-1)" "unprognostic (3.95e-2)" "unprognostic (4.52e-2)" "unprognostic (1.86e-1)" "unprognostic (4.13e-2)" "unprognostic (4.72e-3)" "unprognostic (7.19e-2)" "unprognostic (3.68e-3)" "unprognostic (7.35e-3)" "unprognostic (3.15e-2)" "unprognostic (2.12e-1)" "potential prognostic unfavorable (3.62e-4)" "unprognostic (1.74e-2)" "unprognostic (3.33e-2)" "unprognostic (2.48e-1)" "unprognostic (1.15e-1)" "unprognostic (2.20e-2)" "unprognostic (6.86e-2)" "unprognostic (2.18e-2)" "unprognostic (1.97e-2)" "unprognostic (1.28e-2)" "unprognostic (1.20e-1)" "unprognostic (9.75e-3)" "unprognostic (2.95e-3)" "unprognostic (1.96e-1)" "unprognostic (1.27e-1)" "unprognostic (1.92e-1)" "unprognostic (2.89e-3)" "unprognostic (1.96e-1)" CCDC13 FLJ25467 ENSG00000244607 "Coiled-coil domain containing 13" Q8IYE1 3 42705756-42773253 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 2.7;retina: 4.0;testis: 2.9" "Cell type enhanced" "Detected in some" "Astrocytes: 5.9;Choroid plexus epithelial cells: 19.6;Distal convoluted tubule cells: 6.6;Endometrial ciliated cells: 7.7;Ependymal cells: 69.4;Epididymal efferent duct ciliated cells: 13.4;Fallopian tube ciliated cells: 7.9;Loop of henle epithelial cells: 7.5;Podocytes: 6.7;Proximal tubule cells: 5.7;Renal collecting duct intercalated cells: 7.1;Renal collecting duct principal cells: 7.0;Renal connecting tubule cells: 6.3" "Group enriched" "Detected in many" 5 "choroid plexus epithelial cell: 19.4;ependymal cell: 71.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA047429 Approved "Nucleoplasm,Centriolar satellite,Basal body,Cytosol" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 34: Ciliated cells - Cilia assembly & function" 37 "Centriolar satellite, Basal body" "Nucleoplasm, Cytosol" "HPA047429: " "unprognostic (4.70e-2)" "unprognostic (2.75e-2)" "unprognostic (6.76e-2)" CCDC134 FLJ22349 ENSG00000100147 "Coiled-coil domain containing 134" Q9H6E4 22 41800679-41832164 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 66.8;Cone photoreceptor cells: 64.2" "Cell type enhanced" "Detected in all" "cerebellar inhibitory: 43.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003936, HPA075348" Approved Supported Vesicles,Cytosol "Secreted to blood" "No annotated function" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 40: Non-specific - Mixed function" "Cluster 25: Non-specific - Transcription" "Cluster 66: Non-specific - Mitochondria" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 3 Cytosol Vesicles "HPA003936: , HPA075348: " "unprognostic (1.18e-1)" "unprognostic (2.97e-2)" "unprognostic (1.84e-3)" "unprognostic (2.47e-1)" "unprognostic (2.53e-2)" "unprognostic (1.40e-1)" "unprognostic (2.88e-1)" "unprognostic (7.16e-2)" "unprognostic (7.01e-2)" "unprognostic (6.09e-3)" "potential prognostic favorable (3.77e-6)" "unprognostic (1.47e-3)" "unprognostic (1.67e-2)" "potential prognostic unfavorable (2.97e-6)" "unprognostic (9.72e-2)" "unprognostic (1.21e-1)" "unprognostic (2.18e-2)" "unprognostic (4.28e-2)" "potential prognostic favorable (3.95e-5)" "unprognostic (4.61e-2)" "unprognostic (1.23e-1)" "unprognostic (1.03e-1)" "unprognostic (2.10e-1)" "unprognostic (8.83e-2)" "unprognostic (5.35e-3)" "unprognostic (1.37e-1)" "unprognostic (2.62e-1)" "unprognostic (7.59e-2)" "unprognostic (2.10e-1)" "unprognostic (3.20e-2)" "unprognostic (1.61e-2)" CCDC136 "DKFZP434G156, KIAA1793, NAG6" ENSG00000128596 "Coiled-coil domain containing 136" Q96JN2 7 128790757-128822132 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Fertilization, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 82.4;retina: 48.7;testis: 175.1" "Cell type enhanced" "Detected in many" "Early spermatids: 787.0;Late primary spermatocytes: 1028.7;Late spermatids: 3444.6;Retinal bipolar cells: 333.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 15.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 25.2" "Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010646, HPA071015" Enhanced Approved Approved "Golgi apparatus,Vesicles,Plasma membrane,Mid piece" NA NA "Cluster 67: Testis - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 9 "Plasma membrane" "Golgi apparatus, Vesicles, Mid piece" "HPA010646: , HPA071015: " "unprognostic (3.44e-1)" "unprognostic (1.44e-1)" "unprognostic (9.71e-2)" "unprognostic (7.73e-2)" "unprognostic (1.23e-2)" "unprognostic (1.62e-2)" "unprognostic (2.98e-1)" "unprognostic (1.26e-2)" "unprognostic (3.28e-1)" "unprognostic (1.15e-1)" "unprognostic (2.49e-1)" "unprognostic (5.46e-3)" "unprognostic (6.28e-2)" "unprognostic (7.94e-3)" "unprognostic (2.62e-1)" "unprognostic (2.84e-1)" "unprognostic (1.35e-1)" "unprognostic (6.90e-3)" "unprognostic (3.47e-3)" "unprognostic (4.36e-3)" "unprognostic (7.51e-3)" CCDC137 MGC16597 ENSG00000185298 "Coiled-coil domain containing 137" Q6PK04 17 81666737-81673904 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 107.6;Esophageal basal cells: 92.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053914, HPA072411" Uncertain Supported "Nucleoplasm,Nucleoli,Mitotic chromosome" Yes No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 17: Non-specific - RNA processing" 68 Nucleoli "Nucleoplasm, Mitotic chromosome" "HPA053914: , HPA072411: " "unprognostic (7.29e-2)" "unprognostic (1.20e-2)" "unprognostic (1.01e-1)" "unprognostic (2.89e-1)" "unprognostic (2.60e-1)" "unprognostic (7.72e-2)" "unprognostic (1.47e-1)" "unprognostic (4.69e-1)" "unprognostic (2.08e-1)" "unprognostic (5.18e-2)" "validated prognostic unfavorable (2.80e-7)" "validated prognostic unfavorable (3.32e-4)" "unprognostic (1.95e-1)" "validated prognostic unfavorable (1.90e-9)" "validated prognostic unfavorable (4.55e-4)" "validated prognostic unfavorable (2.98e-4)" "validated prognostic unfavorable (1.79e-4)" "unprognostic (1.17e-1)" "unprognostic (1.45e-2)" "unprognostic (8.01e-2)" "unprognostic (6.56e-3)" "unprognostic (1.58e-1)" "unprognostic (6.69e-3)" "unprognostic (3.52e-2)" "unprognostic (6.19e-2)" "unprognostic (1.51e-1)" "unprognostic (5.56e-3)" "unprognostic (7.88e-2)" "unprognostic (2.85e-1)" "unprognostic (9.16e-2)" "unprognostic (1.88e-2)" CCDC138 FLJ32745 ENSG00000163006 "Coiled-coil domain containing 138" Q96M89 2 108786757-108885477 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 10.2" "Cell type enhanced" "Detected in many" "Early spermatids: 205.3;Endometrial ciliated cells: 232.5;Ependymal cells: 200.0;Late primary spermatocytes: 211.8;pDCs: 306.1;Respiratory ciliated cells: 259.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049899, HPA054223" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 2: Neurons - Nucleosome" "Cluster 59: Leukemia - T-cell receptor" "Cluster 20: Non-specific - Transcription regulation" 18 Nucleoplasm Cytosol "HPA049899: , HPA054223: " "unprognostic (4.43e-2)" "unprognostic (1.28e-1)" "unprognostic (1.02e-2)" "unprognostic (1.12e-1)" "unprognostic (1.65e-1)" "unprognostic (4.09e-3)" "unprognostic (4.93e-2)" "unprognostic (2.34e-1)" "unprognostic (1.78e-1)" "unprognostic (5.79e-3)" "unprognostic (1.54e-1)" "unprognostic (1.50e-2)" "potential prognostic unfavorable (1.25e-4)" "unprognostic (1.15e-2)" "unprognostic (2.39e-3)" "unprognostic (1.49e-1)" "unprognostic (3.24e-3)" "unprognostic (1.18e-2)" "unprognostic (2.71e-1)" "unprognostic (7.73e-2)" "unprognostic (4.30e-3)" "unprognostic (1.87e-3)" "unprognostic (4.08e-2)" "unprognostic (2.90e-2)" "unprognostic (3.57e-2)" "unprognostic (2.43e-3)" "unprognostic (2.53e-1)" "unprognostic (7.82e-3)" "unprognostic (1.33e-2)" CCDC14 "DKFZp434L1050, FLJ12892" ENSG00000175455 "Coiled-coil domain containing 14" Q49A88 3 123897305-123961408 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Tuft cells: 403.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA035278, HPA035279" Uncertain Enhanced "Microtubules,Primary cilium,Centriolar satellite,Basal body" NA Yes "Cluster 5: Non-specific - Cell proliferation" "Cluster 40: Non-specific - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 28: Astrocytes - Homeostasis & neuron support" 36 "Centriolar satellite" "Microtubules, Primary cilium, Basal body" "HPA035278: , HPA035279: " "unprognostic (5.08e-1)" "unprognostic (1.47e-1)" "unprognostic (1.36e-1)" "unprognostic (1.80e-2)" "unprognostic (1.10e-1)" "unprognostic (5.24e-2)" "unprognostic (8.13e-2)" "unprognostic (5.64e-2)" "unprognostic (1.95e-3)" "unprognostic (7.81e-3)" "potential prognostic unfavorable (2.70e-5)" "unprognostic (2.80e-2)" "unprognostic (2.39e-1)" "unprognostic (1.07e-3)" "unprognostic (1.24e-1)" "unprognostic (1.55e-1)" "unprognostic (3.64e-1)" "unprognostic (1.75e-1)" "unprognostic (1.15e-1)" "unprognostic (1.26e-1)" "unprognostic (1.31e-1)" "unprognostic (4.84e-2)" "unprognostic (2.15e-3)" "unprognostic (2.33e-3)" "potential prognostic favorable (3.62e-4)" "unprognostic (5.60e-2)" "unprognostic (4.20e-2)" "unprognostic (1.32e-2)" "unprognostic (3.09e-1)" "unprognostic (2.54e-1)" "unprognostic (3.26e-2)" CCDC141 "CAMDI, FLJ39502" ENSG00000163492 "Coiled-coil domain containing 141" Q6ZP82 2 178829757-179050137 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "heart muscle: 69.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 439.3;Cardiomyocytes: 586.3;Cholangiocytes: 147.1;Early spermatids: 82.5;Lymphatic endothelial cells: 89.7;Macrophages: 92.5;Mast cells: 121.5;Myonuclei: 79.2;Pancreatic duct cells: 113.8;Retinal bipolar cells: 97.6;Sertoli cells: 94.8;Thymocytes: 74.5" "Group enriched" "Detected in many" 4 "astrocyte: 39.0;endothelial cell: 115.1;pericyte: 125.9" "Cancer enhanced" "Detected in single" "Testicular Germ Cell Tumor (TCGA): 1.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 14.4" "Group enriched" "Detected in many" 9 "B-cells: 7.9;T-cells: 14.4" "Cancer enhanced" "Detected in some" "lymphoma: 3.0;Sarcoma: 2.3" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012718 Approved Nucleoplasm NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 35: Non-specific - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" Nucleoplasm "HPA012718: " "unprognostic (2.26e-2)" "unprognostic (1.81e-1)" "unprognostic (8.19e-2)" "unprognostic (2.06e-1)" "unprognostic (2.08e-1)" "unprognostic (1.40e-3)" "unprognostic (8.62e-2)" CCDC142 FLJ14397 ENSG00000135637 "Coiled-coil domain containing 142" Q17RM4 2 74471986-74483408 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA056946 Approved NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 67: Plasma cells - Plasma cell differentiation" "HPA056946: " "unprognostic (2.99e-1)" "unprognostic (1.08e-1)" "unprognostic (5.32e-3)" "unprognostic (3.06e-3)" "unprognostic (7.51e-3)" "unprognostic (2.07e-1)" "unprognostic (9.37e-2)" "potential prognostic favorable (3.02e-4)" "unprognostic (6.78e-3)" "unprognostic (2.52e-3)" "unprognostic (4.05e-3)" "unprognostic (2.83e-1)" "unprognostic (5.77e-2)" "potential prognostic unfavorable (8.88e-6)" "unprognostic (9.61e-2)" "unprognostic (2.14e-1)" "unprognostic (2.44e-3)" "unprognostic (7.76e-2)" "unprognostic (4.16e-3)" "unprognostic (1.47e-2)" "unprognostic (2.97e-1)" "unprognostic (5.16e-2)" "unprognostic (1.96e-3)" "unprognostic (4.16e-2)" "unprognostic (6.35e-3)" "unprognostic (1.30e-1)" "unprognostic (3.01e-2)" "unprognostic (2.11e-1)" "unprognostic (1.45e-1)" "unprognostic (5.11e-2)" "unprognostic (1.52e-2)" CCDC144A "FLJ43983, KIAA0565" ENSG00000170160 "Coiled-coil domain containing 144A" A2RUR9 17 16689537-16777881 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 11.9" "Cell type enhanced" "Detected in some" "Astrocytes: 56.6;Bergmann glia: 43.8;Brain excitatory neurons: 76.3;Brain inhibitory neurons: 49.3;Ependymal cells: 13.3;Microglia: 24.9;Oligodendrocyte progenitor cells: 62.6;Oligodendrocytes: 59.6;Other brain neurons: 22.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "HPA022996, HPA023009, HPA047851, HPA066260" Enhanced Approved "Cell Junctions,Cytosol" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 9: Non-specific - Receptor signaling" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 35: Neurons - Synaptic function & neurogenesis" 1 Cytosol "Cell Junctions" "HPA022996: , HPA023009: , HPA047851: , HPA066260: " "unprognostic (2.63e-2)" "unprognostic (1.40e-1)" "unprognostic (1.30e-1)" "unprognostic (1.64e-1)" "unprognostic (1.04e-2)" "unprognostic (1.78e-2)" "unprognostic (1.57e-1)" "unprognostic (1.37e-1)" CCDC146 "KIAA1505, MBO2" ENSG00000135205 "Coiled-coil domain containing 146" Q8IYE0 7 77122434-77329533 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "fallopian tube: 32.0;testis: 20.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 400.8;Endometrial ciliated cells: 702.1;Ependymal cells: 730.8;Epididymal efferent duct absorptive cells: 594.5;Epididymal efferent duct ciliated cells: 952.7;Fallopian tube ciliated cells: 806.4;Late primary spermatocytes: 563.2;Respiratory ciliated cells: 1054.6" "Cell type enhanced" "Detected in all" "ependymal cell: 801.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 14.4;neutrophil: 15.5" "Group enriched" "Detected in many" 4 "granulocytes: 15.5;NK-cells: 5.4;T-cells: 4.4" "Low cancer specificity" "Detected in many" "Liver - Hepatic stellate cells, Lung - Respiratory ciliated cells, Prostate - Urothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA020082, HPA020105" Uncertain NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 24: Non-specific - Unknown function" "Cluster 107: Ciliated cells - Cilia assembly & function" 46 "HPA020082: , HPA020105: " "unprognostic (1.67e-1)" "unprognostic (2.08e-1)" "unprognostic (3.37e-2)" "unprognostic (4.21e-1)" "unprognostic (5.37e-2)" "unprognostic (1.70e-1)" "unprognostic (8.87e-2)" "unprognostic (4.09e-3)" "potential prognostic favorable (9.54e-4)" "unprognostic (6.43e-2)" "unprognostic (6.73e-3)" "unprognostic (2.18e-3)" "unprognostic (5.60e-2)" "unprognostic (7.04e-2)" "unprognostic (7.44e-2)" "unprognostic (6.69e-2)" "unprognostic (7.82e-2)" "unprognostic (8.10e-3)" "unprognostic (6.80e-2)" "unprognostic (1.07e-1)" "unprognostic (5.12e-2)" "unprognostic (1.11e-2)" "unprognostic (1.99e-1)" "potential prognostic favorable (7.59e-4)" "potential prognostic unfavorable (2.03e-4)" "unprognostic (3.34e-1)" CCDC148 MGC125588 ENSG00000153237 "Coiled-coil domain containing 148" Q8NFR7 2 158171073-158456753 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 4.6" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 255.4;Distal convoluted tubule cells: 501.4;Ependymal cells: 255.7;Loop of henle epithelial cells: 388.9;Pituicytes/FSCs: 178.7;Pituitary stem cells: 168.5;Podocytes: 294.2;Respiratory ciliated cells: 281.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Kidney Renal Papillary Cell Carcinoma (TCGA): 1.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" HPA042626 Uncertain Uncertain "Nucleoplasm,Nucleoli,Nucleoli rim" No No "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 44: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 5 "Nucleoplasm, Nucleoli, Nucleoli rim" "HPA042626: " "unprognostic (1.14e-1)" "unprognostic (9.22e-3)" "potential prognostic favorable (4.74e-4)" "unprognostic (6.51e-2)" "unprognostic (5.62e-2)" "unprognostic (1.93e-1)" "unprognostic (3.45e-1)" "unprognostic (2.09e-2)" CCDC149 DKFZp761B107 ENSG00000181982 "Coiled-coil domain containing 149" Q6ZUS6 4 24803514-24980204 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "classical monocyte: 1.5" "Lineage enriched" "Detected in single" 5 "monocytes: 1.5" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Spleen - Endothelial cells, Stomach - Chief cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044158, HPA047913" Uncertain Approved Nucleoli NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 70: Non-specific - Protein processing" "Cluster 53: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" Nucleoli "HPA044158: , HPA047913: " "unprognostic (1.53e-2)" "unprognostic (1.07e-1)" "unprognostic (2.89e-2)" "unprognostic (1.13e-1)" "potential prognostic favorable (6.69e-4)" "unprognostic (1.55e-1)" "unprognostic (1.31e-1)" "unprognostic (2.69e-2)" "unprognostic (8.38e-3)" "unprognostic (1.01e-1)" "validated prognostic favorable (3.59e-7)" "validated prognostic favorable (4.44e-4)" "unprognostic (2.26e-2)" "potential prognostic unfavorable (1.45e-6)" "unprognostic (5.87e-2)" "unprognostic (5.10e-2)" "unprognostic (2.91e-2)" "unprognostic (4.17e-2)" "unprognostic (7.96e-2)" "unprognostic (1.40e-1)" "unprognostic (1.87e-1)" "unprognostic (7.28e-2)" "unprognostic (4.46e-1)" "unprognostic (1.39e-1)" "unprognostic (2.07e-1)" "unprognostic (2.39e-2)" "unprognostic (5.84e-2)" "unprognostic (1.23e-1)" "unprognostic (1.40e-1)" "unprognostic (1.07e-2)" "unprognostic (5.70e-3)" CCDC15 FLJ13215 ENSG00000149548 "Coiled-coil domain containing 15" Q0P6D6 11 124954121-125041489 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 9.8" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 120.4;Early spermatids: 64.7;Erythrocyte progenitors: 70.0;Late primary spermatocytes: 74.1;Late spermatids: 62.4;Megakaryocyte progenitors: 38.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Spermatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA040450, HPA041738" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 57: Testis - Spermatogenesis" "Cluster 11: White matter - Signal transduction" "Cluster 24: Non-specific - Unknown function" "Cluster 3: Early primary spermatocytes - Early meiosis" "Plasma membrane" Cytosol "HPA040450: , HPA041738: " "unprognostic (2.28e-1)" "unprognostic (5.71e-2)" "unprognostic (1.15e-1)" "unprognostic (2.50e-1)" "unprognostic (1.44e-1)" "unprognostic (2.50e-1)" "unprognostic (2.86e-3)" "potential prognostic favorable (4.56e-4)" "unprognostic (1.24e-2)" "unprognostic (4.67e-1)" "unprognostic (3.57e-3)" "unprognostic (5.06e-2)" "unprognostic (1.34e-1)" "unprognostic (8.46e-2)" "unprognostic (1.95e-2)" "potential prognostic unfavorable (1.71e-4)" "unprognostic (1.47e-2)" "unprognostic (4.69e-3)" "unprognostic (2.42e-2)" "unprognostic (3.54e-2)" "unprognostic (4.09e-2)" "unprognostic (2.54e-1)" CCDC150 FLJ39660 ENSG00000144395 "Coiled-coil domain containing 150" Q8NCX0 2 196639554-196763490 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 2.4;testis: 4.6" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 29.7;Early primary spermatocytes: 43.3;Early spermatids: 36.6;Erythrocyte progenitors: 25.2;Late primary spermatocytes: 83.2;Late spermatids: 22.1;Monocyte progenitors: 29.8;Oligodendrocytes: 21.9;Oocytes: 32.2;Undifferentiated spermatogonia: 37.8" "Cell type enhanced" "Detected in all" "oligodendrocyte: 32.0" "Cancer enhanced" "Detected in some" "Kidney Renal Clear Cell Carcinoma (TCGA): 2.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA048104 Uncertain Approved Nucleoplasm NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" 3 Nucleoplasm "HPA048104: " "unprognostic (1.57e-1)" "unprognostic (3.62e-1)" "potential prognostic favorable (1.84e-7)" "unprognostic (8.71e-3)" "unprognostic (4.87e-1)" "unprognostic (1.37e-1)" "unprognostic (7.44e-2)" "potential prognostic unfavorable (1.88e-4)" "unprognostic (3.48e-1)" CCDC152 LOC100129792 ENSG00000198865 "Coiled-coil domain containing 152" Q4G0S7 5 42756818-42802439 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "liver: 125.8" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 38.2;Early primary spermatocytes: 164.3;Pituicytes/FSCs: 48.0;Retinal horizontal cells: 38.1" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in all" 7 "Liver Hepatocellular Carcinoma (TCGA): 40.5;Prostate Adenocarcinoma (TCGA): 108.1;Uterine Corpus Endometrial Carcinoma (TCGA): 40.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Bile duct cancer: 8.7" "Adrenal gland - Macrophages, Liver - Hepatocytes, Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA036240 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 1: T-cells - Unknown function" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 20: Myeloma - Immune response" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 4 Nucleoplasm Cytosol "HPA036240: " "unprognostic (2.24e-3)" "unprognostic (1.49e-1)" "unprognostic (2.14e-1)" "unprognostic (9.07e-3)" "unprognostic (1.51e-1)" "unprognostic (3.64e-1)" "unprognostic (2.18e-3)" "potential prognostic unfavorable (3.23e-4)" "unprognostic (5.14e-2)" "unprognostic (1.33e-1)" "unprognostic (1.07e-2)" "unprognostic (2.98e-3)" "unprognostic (5.36e-2)" "unprognostic (1.05e-1)" "potential prognostic favorable (5.65e-4)" "unprognostic (1.82e-2)" "unprognostic (5.62e-2)" "unprognostic (1.05e-2)" "unprognostic (4.37e-2)" "unprognostic (8.86e-3)" "unprognostic (1.04e-3)" "potential prognostic favorable (7.11e-4)" "unprognostic (2.09e-2)" "unprognostic (8.32e-2)" "unprognostic (3.13e-1)" "unprognostic (1.87e-1)" "unprognostic (4.86e-2)" "unprognostic (4.06e-3)" "unprognostic (6.02e-2)" "unprognostic (1.26e-1)" "unprognostic (2.96e-1)" CCDC153 LOC283152 ENSG00000248712 "Coiled-coil domain containing 153" Q494R4 11 119190250-119196769 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 23.3;fallopian tube: 22.8" "Group enriched" "Detected in many" 4 "Endometrial ciliated cells: 112.4;Epididymal efferent duct ciliated cells: 242.6;Fallopian tube ciliated cells: 256.8;Respiratory ciliated cells: 256.8" "Cell type enriched" "Detected in some" 6 "ependymal cell: 59.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 24.3" "Lineage enriched" "Detected in many" 9 "granulocytes: 24.3" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA041497 Uncertain Approved Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 48: Non-specific - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" 6 Cytosol "HPA041497: " "unprognostic (1.29e-2)" "unprognostic (6.93e-2)" "unprognostic (3.06e-2)" "unprognostic (1.65e-1)" "unprognostic (2.45e-1)" "unprognostic (1.64e-1)" "unprognostic (7.01e-2)" "unprognostic (1.02e-1)" "unprognostic (1.51e-1)" "unprognostic (3.16e-1)" "unprognostic (1.16e-1)" "unprognostic (5.15e-2)" "unprognostic (2.67e-1)" "unprognostic (2.61e-1)" "potential prognostic favorable (9.77e-4)" "unprognostic (3.82e-1)" "unprognostic (2.01e-1)" "unprognostic (1.21e-2)" "unprognostic (1.99e-1)" "unprognostic (2.28e-1)" "unprognostic (3.52e-2)" "unprognostic (2.78e-1)" "unprognostic (2.54e-1)" "unprognostic (5.97e-2)" "unprognostic (1.63e-1)" "unprognostic (3.95e-1)" "unprognostic (1.49e-1)" "unprognostic (1.48e-1)" CCDC154 "C16orf29, LOC645811" ENSG00000197599 "Coiled-coil domain containing 154" A6NI56 16 1434383-1444556 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 11.9" "Cell type enhanced" "Detected in many" "Early spermatids: 49.6;Late primary spermatocytes: 49.0;Late spermatids: 14.1;Melanocytes: 11.7;Retinal amacrine cells: 12.8;Retinal horizontal cells: 14.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Prostate Adenocarcinoma (TCGA): 9.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "thyroid cancer: 15.4" "Colon - Enteric glia cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "cerebellum: 3.6" "HPA041158, HPA043535, HPA048237" Uncertain Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 67: Testis - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" "Plasma membrane" "Golgi apparatus" "HPA041158: , HPA043535: , HPA048237: " "unprognostic (6.79e-2)" "unprognostic (1.11e-1)" "unprognostic (1.47e-3)" "unprognostic (5.04e-2)" "potential prognostic favorable (2.27e-4)" "unprognostic (9.80e-2)" "unprognostic (2.06e-1)" "unprognostic (1.29e-1)" "unprognostic (1.19e-1)" "unprognostic (1.78e-2)" CCDC157 ENSG00000187860 "Coiled-coil domain containing 157" Q569K6 22 30356635-30378673 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "testis: 30.0" "Cell type enhanced" "Detected in many" "Early spermatids: 115.7;Endometrial ciliated cells: 55.6;Ependymal cells: 46.7;Epididymal efferent duct ciliated cells: 68.4;Fallopian tube ciliated cells: 71.2;Late primary spermatocytes: 135.0;Late spermatids: 236.6;Respiratory ciliated cells: 84.5;Rod photoreceptor cells: 47.8" "Cell type enhanced" "Detected in all" "ependymal cell: 55.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" HPA042943 Uncertain NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 1 "HPA042943: " "unprognostic (9.74e-3)" "unprognostic (2.78e-2)" "unprognostic (2.00e-2)" "unprognostic (8.32e-2)" "unprognostic (7.50e-2)" "unprognostic (3.17e-2)" "unprognostic (1.28e-1)" "unprognostic (2.51e-1)" "unprognostic (7.09e-3)" "unprognostic (1.46e-1)" "unprognostic (3.09e-1)" "unprognostic (2.22e-1)" "unprognostic (1.08e-2)" "unprognostic (4.24e-1)" "unprognostic (1.13e-2)" "unprognostic (2.00e-1)" "unprognostic (2.62e-2)" "unprognostic (3.39e-2)" "unprognostic (5.52e-2)" "unprognostic (2.87e-1)" "unprognostic (1.31e-3)" "unprognostic (2.28e-2)" "unprognostic (1.48e-1)" "unprognostic (6.84e-3)" "unprognostic (1.27e-2)" "unprognostic (2.05e-1)" "unprognostic (6.80e-2)" "unprognostic (2.92e-1)" "unprognostic (1.30e-1)" "unprognostic (1.97e-2)" CCDC158 FLJ25770 ENSG00000163749 "Coiled-coil domain containing 158" Q5M9N0 4 76312997-76421868 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "testis: 32.0" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 58.1;Early spermatids: 71.1;Gonadotrophs: 74.3;Late primary spermatocytes: 170.1;Late spermatids: 144.1;Pituicytes/FSCs: 29.8" "Cell type enhanced" "Detected in many" "mammillary body: 42.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Adipocytes (Visceral), Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 53: Neurons - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 3 "unprognostic (8.05e-2)" "unprognostic (9.01e-3)" CCDC159 ENSG00000183401 "Coiled-coil domain containing 159" P0C7I6 19 11344684-11354944 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Cardiomyocytes: 199.1;Early spermatids: 369.6;Late spermatids: 378.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047126, HPA054655" Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 6: Non-specific - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" "Nucleoplasm, Nuclear bodies" Cytosol "HPA047126: , HPA054655: " "unprognostic (2.95e-1)" "unprognostic (1.20e-1)" "unprognostic (2.26e-3)" "unprognostic (4.82e-3)" "unprognostic (1.68e-1)" "unprognostic (1.14e-1)" "unprognostic (1.27e-2)" "unprognostic (1.78e-1)" "unprognostic (1.53e-3)" "unprognostic (4.25e-1)" "unprognostic (1.40e-3)" "unprognostic (1.91e-1)" "potential prognostic favorable (1.43e-7)" "unprognostic (6.65e-2)" "unprognostic (1.33e-2)" "unprognostic (1.29e-2)" "unprognostic (2.11e-1)" "unprognostic (2.56e-1)" "unprognostic (3.28e-2)" "unprognostic (2.14e-3)" "unprognostic (9.88e-2)" "potential prognostic favorable (1.78e-4)" "unprognostic (2.16e-2)" "unprognostic (1.90e-1)" "unprognostic (9.49e-3)" "unprognostic (2.38e-1)" "unprognostic (1.98e-1)" "unprognostic (2.78e-1)" "unprognostic (2.80e-2)" "unprognostic (5.51e-3)" "unprognostic (5.12e-3)" CCDC160 ENSG00000203952 "Coiled-coil domain containing 160" A6NGH7 X 134237047-134246842 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "salivary gland: 12.3" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 21.4;Endometrial ciliated cells: 32.0;Epididymal efferent duct ciliated cells: 40.7;Fallopian tube ciliated cells: 38.6;Lacrimal acinar cells: 37.1;Oocytes: 46.1;Respiratory ciliated cells: 47.2;Respiratory deuterosomal cells: 21.8;Salivary acinar cells: 31.0;Salivary duct cells: 21.7" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 16.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 2.5" "Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 21: Non-specific - Metabolism" "Cluster 5: Rhabdoid - Unknown function" "Cluster 38: Secretory epithelial cells - Exocrine secretion" "unprognostic (3.00e-2)" "unprognostic (8.33e-2)" "unprognostic (3.92e-3)" "unprognostic (1.44e-1)" "unprognostic (4.14e-2)" "unprognostic (2.44e-1)" "unprognostic (2.91e-2)" "unprognostic (4.24e-3)" "potential prognostic favorable (1.68e-6)" "unprognostic (1.01e-1)" "unprognostic (3.24e-1)" "potential prognostic favorable (1.77e-5)" "unprognostic (1.29e-1)" "unprognostic (1.30e-1)" "unprognostic (4.57e-2)" "unprognostic (6.33e-2)" CCDC163 "C1orf231, CCDC163P, LOC126661" ENSG00000280670 "CCDC163 homolog" A0A0D9SF12 1 45493866-45500079 "Essential proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in single" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 7.1;Astrocytes: 17.8;Bergmann glia: 9.5;Breast lactating cells: 9.0;Breast myoepithelial cells: 8.6;Plasma cells: 8.3" "Cell type enhanced" "Detected in all" "astrocyte: 23.7;Bergmann glia: 14.6" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 3.3" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" HPA053619 Approved Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 70: Non-specific - Protein processing" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 28: Astrocytes - Homeostasis & neuron support" Cytosol "HPA053619: " "unprognostic (2.60e-3)" "unprognostic (7.85e-3)" "unprognostic (1.58e-1)" "unprognostic (1.17e-1)" "unprognostic (7.79e-2)" CCDC166 ENSG00000255181 "Coiled-coil domain containing 166" P0CW27 8 143706694-143708109 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 32 "testis: 3.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" HPA025058 Uncertain NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 98: Neurons - Neurotransmission & signaling" "HPA025058: " CCDC167 "C6orf129, dJ153P14.2" ENSG00000198937 "Coiled-coil domain containing 167" Q9P0B6 6 37482938-37499893 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 124.6;Esophageal apical cells: 184.6;Esophageal suprabasal cells: 131.4;Extravillous trophoblasts: 130.2;Hepatocytes: 159.4;Late primary spermatocytes: 143.8;Late spermatids: 463.2;Oocytes: 211.8;Plasma cells: 167.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "B-cells: 145.9;granulocytes: 140.8;T-cells: 424.9" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045215 Uncertain Approved Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 8: Non-specific - Secretory pathway" 34 Cytosol "HPA045215: " "unprognostic (1.37e-1)" "unprognostic (1.97e-2)" "unprognostic (5.18e-2)" "unprognostic (9.15e-2)" "unprognostic (2.80e-1)" "unprognostic (1.58e-1)" "unprognostic (1.54e-2)" "unprognostic (5.96e-2)" "unprognostic (5.66e-2)" "potential prognostic unfavorable (2.18e-4)" "unprognostic (7.08e-3)" "potential prognostic unfavorable (5.86e-4)" "validated prognostic unfavorable (3.31e-6)" "validated prognostic unfavorable (6.01e-5)" "unprognostic (4.12e-2)" "unprognostic (1.88e-1)" "unprognostic (1.28e-1)" "unprognostic (3.61e-1)" "unprognostic (7.51e-3)" "unprognostic (1.43e-1)" "unprognostic (6.60e-2)" "unprognostic (1.07e-1)" "unprognostic (1.68e-1)" "unprognostic (2.01e-1)" "unprognostic (2.05e-1)" "unprognostic (1.04e-1)" "unprognostic (2.33e-1)" "unprognostic (6.17e-2)" "unprognostic (7.12e-2)" "unprognostic (1.03e-1)" CCDC168 "C13orf40, FLJ40176" ENSG00000175820 "Coiled-coil domain containing 168" Q8NDH2 13 102729367-102759072 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 54 "testis: 8.4" "Cell type enriched" "Detected in some" 25 "Early spermatids: 1551.4" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 4.9" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "HPA048184, HPA058793" Uncertain Approved "Plasma membrane" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 53: Neurons - Mixed function" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" "Plasma membrane" "HPA048184: , HPA058793: " CCDC169 "C13orf38, LOC728591, RP11-251J8.1" ENSG00000242715 "Coiled-coil domain containing 169" A6NNP5 13 36222008-36297840 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "testis: 55.6" "Group enriched" "Detected in some" 5 "Early spermatids: 700.4;Late spermatids: 2736.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA040527 Approved "Nucleoplasm,Nuclear speckles,Vesicles" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 9: Non-specific - Receptor signaling" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" Nucleoplasm "Nuclear speckles, Vesicles" "HPA040527: " "unprognostic (1.86e-1)" "unprognostic (3.64e-2)" "unprognostic (5.56e-2)" "unprognostic (2.30e-1)" "unprognostic (1.85e-1)" "unprognostic (1.95e-1)" "unprognostic (2.12e-1)" "unprognostic (2.83e-2)" "unprognostic (1.25e-1)" "unprognostic (1.69e-2)" "unprognostic (1.13e-1)" "unprognostic (1.41e-1)" CCDC169-SOHLH2 C13orf38-SOHLH2 ENSG00000250709 "CCDC169-SOHLH2 readthrough" 13 36168794-36297842 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 22 "testis: 9.6" "Group enriched" "Detected in some" 4 "Early spermatids: 11.3;Late primary spermatocytes: 7.6;Late spermatids: 22.7;Oocytes: 18.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA029182 Approved Vesicles NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" Vesicles "HPA029182: " CCDC17 FLJ33084 ENSG00000159588 "Coiled-coil domain containing 17" Q96LX7 1 45620044-45624057 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "fallopian tube: 33.9" "Group enriched" "Detected in many" 9 "Endometrial ciliated cells: 96.5;Epididymal efferent duct ciliated cells: 128.8;Fallopian tube ciliated cells: 205.7;Respiratory ciliated cells: 202.3" "Cell type enriched" "Detected in some" 10 "ependymal cell: 22.0" "Group enriched" "Detected in some" 4 "Lung Adenocarcinoma (TCGA): 1.4;Uterine Corpus Endometrial Carcinoma (TCGA): 4.4" "Region enhanced" "Detected in some" "midbrain: 1.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells" "Not detected" "Not detected" HPA028338 Enhanced NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 107: Ciliated cells - Cilia assembly & function" 3 "HPA028338: " "unprognostic (1.26e-1)" "unprognostic (1.23e-3)" "unprognostic (2.62e-1)" "unprognostic (1.31e-1)" "unprognostic (3.84e-3)" "unprognostic (4.65e-1)" CCDC170 "bA282P11.1, C6orf97, FLJ23305" ENSG00000120262 "Coiled-coil domain containing 170" Q8IYT3 6 151494017-151621193 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 11.0;fallopian tube: 31.4" "Group enriched" "Detected in many" 4 "Choroid plexus epithelial cells: 228.3;Endometrial ciliated cells: 332.8;Ependymal cells: 428.0;Epididymal efferent duct ciliated cells: 570.0;Fallopian tube ciliated cells: 671.9;Respiratory ciliated cells: 814.6" "Group enriched" "Detected in all" 9 "choroid plexus epithelial cell: 159.3;ependymal cell: 486.2" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 7.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 6.2" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "breast cancer: 2.1;colorectal cancer: 1.1" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Kidney - Fibroblasts, Lung - Respiratory ciliated cells, Prostate - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA027114, HPA027185" Enhanced Supported "Golgi apparatus,Cell Junctions" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 27: Breast cancer - Unknown function" "Cluster 107: Ciliated cells - Cilia assembly & function" 2 "Golgi apparatus" "Cell Junctions" "HPA027114: , HPA027185: " "unprognostic (1.39e-1)" "unprognostic (4.92e-2)" "potential prognostic favorable (4.97e-4)" "unprognostic (1.42e-1)" "unprognostic (5.81e-2)" "unprognostic (1.84e-1)" "unprognostic (5.03e-3)" "unprognostic (1.87e-2)" "unprognostic (5.21e-2)" "unprognostic (2.37e-1)" "unprognostic (4.20e-1)" "unprognostic (4.69e-1)" "unprognostic (1.51e-1)" "unprognostic (1.08e-1)" "unprognostic (1.29e-1)" "unprognostic (9.02e-2)" "unprognostic (5.80e-2)" "unprognostic (1.52e-1)" "unprognostic (7.54e-2)" CCDC171 "bA536D16.1, bA778P13.1, C9orf93, Em:AL513423.1, FLJ39267, FLJ46740" ENSG00000164989 "Coiled-coil domain containing 171" Q6TFL3 9 15553043-16061663 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 10.5" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 233.6;Hematopoietic stem cells: 329.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.4" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Bone cancer: 8.2" "Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA019803, HPA019806, HPA024133" Uncertain Approved Nucleoplasm,Nucleoli Yes No "Cluster 61: Non-specific - Transcription" "Cluster 9: Non-specific - Receptor signaling" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" Nucleoplasm Nucleoli "HPA019803: , HPA019806: , HPA024133: " "unprognostic (7.02e-3)" "unprognostic (1.75e-2)" "unprognostic (1.39e-2)" "unprognostic (1.96e-1)" "unprognostic (2.12e-1)" "potential prognostic favorable (1.87e-4)" "unprognostic (1.78e-1)" "unprognostic (4.70e-2)" "unprognostic (4.30e-2)" "unprognostic (3.09e-1)" "unprognostic (1.17e-1)" "unprognostic (3.82e-2)" "unprognostic (1.35e-2)" "unprognostic (6.98e-2)" "unprognostic (1.31e-1)" "unprognostic (2.28e-2)" "unprognostic (1.54e-1)" CCDC172 "C10orf96, MGC35062" ENSG00000182645 "Coiled-coil domain containing 172" P0C7W6 10 116324448-116380029 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "retina: 2.9;testis: 11.4" "Cell type enhanced" "Detected in some" "Early primary spermatocytes: 129.8;Early spermatids: 19.1;Late primary spermatocytes: 55.9;Rod photoreceptor cells: 30.2;Undifferentiated spermatogonia: 28.8" "Low cell type specificity" "Detected in some" "Cancer enriched" "Detected in single" 6 "Testicular Germ Cell Tumor (TCGA): 1.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 8 "testis cancer: 1.3" "Adrenal gland - Adrenal medulla cells, Skin - Sebaceous gland cells, Testis - Spermatocytes" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 47: Testis - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 34: Testis cancer - Unknown function" "Cluster 3: Early primary spermatocytes - Early meiosis" 18 "unprognostic (2.40e-2)" CCDC174 "C3orf19, ctr1, FLJ33839" ENSG00000154781 "Coiled-coil domain containing 174" Q6PII3 3 14651762-14672659 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 156.5;Late primary spermatocytes: 158.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043468, HPA060129" Approved Enhanced Nucleoplasm NA NA "Cluster 41: Basophils - Unknown function" "Cluster 54: Non-specific - Ribosome" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 94: Gonadal somatic cells - Mixed function" 7 Nucleoplasm "HPA043468: , HPA060129: " "unprognostic (1.40e-2)" "unprognostic (3.27e-1)" "unprognostic (3.50e-1)" "unprognostic (1.52e-2)" "unprognostic (1.81e-2)" "unprognostic (9.87e-2)" "unprognostic (2.84e-2)" "unprognostic (6.07e-2)" "unprognostic (4.16e-3)" "unprognostic (4.99e-2)" "unprognostic (5.01e-3)" "unprognostic (2.17e-2)" "unprognostic (5.82e-3)" "unprognostic (1.87e-1)" "unprognostic (7.67e-2)" "unprognostic (8.85e-2)" "unprognostic (2.22e-2)" "unprognostic (9.30e-2)" "unprognostic (4.04e-2)" "unprognostic (2.03e-1)" "unprognostic (3.09e-2)" "unprognostic (8.83e-3)" "unprognostic (1.33e-2)" "unprognostic (7.90e-2)" "unprognostic (2.90e-1)" "unprognostic (1.04e-1)" "unprognostic (3.07e-1)" "unprognostic (9.82e-2)" "unprognostic (7.55e-2)" CCDC175 C14orf38 ENSG00000151838 "Coiled-coil domain containing 175" P0C221 14 59504539-59576812 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.1;choroid plexus: 2.6;testis: 2.0" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 90.4;Choroid plexus epithelial cells: 88.0;Early primary spermatocytes: 70.2;Ependymal cells: 187.7;Gonadotrophs: 43.1;Hematopoietic stem cells: 89.3;Megakaryocyte progenitors: 182.9;Pituicytes/FSCs: 42.8;Respiratory ciliated cells: 56.8;Sertoli cells: 76.2" "Group enriched" "Detected in many" 7 "choroid plexus epithelial cell: 71.2;ependymal cell: 184.9;upper rhombic lip: 260.7" "Not detected" "Not detected" "Region enriched" "Detected in all" 5 "cerebellum: 39.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA004200 Uncertain Uncertain Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 2: Cerebellar granular cells - Neuronal signaling" Nucleoplasm "Nucleoli, Cytosol" "HPA004200: " "unprognostic (4.90e-2)" "unprognostic (2.12e-1)" "unprognostic (4.44e-3)" CCDC177 "C14orf162, PLPL" ENSG00000267909 "Coiled-coil domain containing 177" Q9NQR7 14 69569799-69574871 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 4.3;retina: 4.1" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 2.7;Brain inhibitory neurons: 1.3;Cone photoreceptor cells: 4.1;Differentiating spermatogonia: 1.4;Ependymal cells: 3.5;Epididymal principal cells: 1.9;Retinal bipolar cells: 11.4;Retinal horizontal cells: 2.0;Retinal pigment epithelial cells: 4.3;Rod photoreceptor cells: 4.4" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Neuroblastoma: 2.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA077909 Approved Cytosol NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 37: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" Cytosol "HPA077909: " CCDC178 "C18orf34, FLJ44050" ENSG00000166960 "Coiled-coil domain containing 178" Q5BJE1 18 32937402-33441101 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 10.3;ovary: 9.4;testis: 14.5" "Cell type enhanced" "Detected in many" "Corticotrophs: 84.9;Distal convoluted tubule cells: 231.1;Early primary spermatocytes: 70.5;Early spermatids: 79.4;Late primary spermatocytes: 129.4;Late spermatids: 120.4;Loop of henle epithelial cells: 144.1;Renal connecting tubule cells: 466.0;Somatotrophs: 65.9;Undifferentiated spermatogonia: 59.1;Vascular endothelial cells: 65.3" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 49.5;ependymal cell: 41.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Sarcoma: 2.5" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 23: Choroid plexus - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" "unprognostic (4.19e-2)" "potential prognostic favorable (6.89e-5)" "unprognostic (4.23e-2)" "potential prognostic favorable (3.18e-6)" "unprognostic (1.09e-2)" "unprognostic (1.67e-1)" "unprognostic (1.12e-1)" CCDC179 ENSG00000255359 "Coiled-coil domain containing 179" H3BU77 11 22846922-22860474 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 262 "testis: 26.1" "Group enriched" "Detected in some" 43 "Early spermatids: 1464.6;Late spermatids: 2727.6" "Low cell type specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Low region specificity" "Detected in many" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 2 CCDC18 NY-SAR-41 ENSG00000122483 "Coiled-coil domain containing 18" Q5T9S5 1 93179919-93278730 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.0;lymphoid tissue: 5.3;testis: 7.6" "Cell type enhanced" "Detected in many" "Adipocytes: 195.5;Cardiomyocytes: 319.2;Early primary spermatocytes: 225.0;Epicardial cells: 434.4;Monocyte progenitors: 164.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Macrophages, Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA028035 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 54: Immune cells - T cell receptor" "Cluster 37: Non-specific - mRNA processing" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 4 Nucleoplasm Cytosol "HPA028035: " "unprognostic (7.74e-2)" "unprognostic (2.91e-1)" "unprognostic (1.71e-1)" "unprognostic (1.76e-1)" "unprognostic (2.91e-2)" "unprognostic (4.10e-1)" "unprognostic (1.18e-1)" "unprognostic (1.07e-2)" "unprognostic (2.34e-3)" "unprognostic (2.67e-3)" "unprognostic (2.93e-2)" "unprognostic (3.00e-1)" "unprognostic (7.14e-3)" "unprognostic (1.17e-2)" "unprognostic (2.16e-2)" "unprognostic (5.09e-2)" "unprognostic (1.71e-1)" "unprognostic (1.70e-2)" "unprognostic (2.27e-3)" "unprognostic (1.85e-2)" "unprognostic (7.59e-2)" "unprognostic (1.96e-2)" "unprognostic (2.19e-1)" "unprognostic (9.62e-2)" "unprognostic (1.35e-2)" "unprognostic (8.90e-2)" "unprognostic (2.32e-3)" CCDC180 "BDAG1, C9orf174, CFAP76, DKFZp434I2420, FAP76, KIAA1529" ENSG00000197816 "Coiled-coil domain containing 180" 9 97307304-97378751 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 4 "brain: 3.7;choroid plexus: 13.3;fallopian tube: 6.0;retina: 6.0;testis: 12.3" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 21.7;Early spermatids: 5.4;Epididymal efferent duct ciliated cells: 5.9;Loop of henle epithelial cells: 12.6;Podocytes: 26.1;Proximal tubule cells: 17.4;Renal collecting duct intercalated cells: 21.1;Renal collecting duct principal cells: 8.3;Renal connecting tubule cells: 14.2;Respiratory ciliated cells: 5.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Adipose progenitor cells, Lung - Respiratory ciliated cells, Skeletal muscle - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 20: Myeloma - Immune response" "Cluster 105: Non-specific - Mixed function" "unprognostic (1.32e-1)" "unprognostic (5.89e-3)" "unprognostic (1.87e-1)" "unprognostic (2.62e-3)" "unprognostic (5.93e-2)" "unprognostic (5.99e-2)" "unprognostic (2.08e-3)" "unprognostic (2.85e-2)" "potential prognostic unfavorable (1.96e-4)" "unprognostic (5.19e-2)" CCDC181 "C1orf114, FLJ25846" ENSG00000117477 "Coiled-coil domain containing 181" Q5TID7 1 169394870-169460669 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 30.6;retina: 37.0;testis: 24.6" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 121.8;Early spermatids: 264.1;Epididymal efferent duct ciliated cells: 121.3;Fallopian tube ciliated cells: 165.7;Late primary spermatocytes: 379.6;Respiratory ciliated cells: 173.0;Rod photoreceptor cells: 116.5" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 6.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "basophil: 1.0" "Lineage enriched" "Detected in single" 10 "granulocytes: 1.0" "Cancer enhanced" "Detected in many" "Neuroblastoma: 6.8" "Adrenal gland - Adrenal medulla cells, Lung - Respiratory ciliated cells, Prostate - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027189, HPA027275, HPA027281, HPA027312" Enhanced Approved "Nuclear speckles,Acrosome,Mid piece,Principal piece" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 40: Non-specific - Unknown function" "Cluster 107: Ciliated cells - Cilia assembly & function" "Nuclear speckles, Acrosome, Mid piece" "Principal piece" "HPA027189: , HPA027275: , HPA027281: , HPA027312: " "unprognostic (3.22e-2)" "unprognostic (8.22e-2)" "unprognostic (2.83e-2)" "unprognostic (1.17e-1)" "unprognostic (1.75e-3)" "unprognostic (4.97e-2)" "unprognostic (5.64e-2)" "unprognostic (1.39e-1)" "unprognostic (2.65e-1)" "unprognostic (7.06e-2)" "unprognostic (2.10e-1)" "unprognostic (8.16e-2)" "unprognostic (2.72e-2)" "unprognostic (3.04e-2)" "unprognostic (2.84e-2)" CCDC182 ENSG00000166329 "Coiled-coil domain containing 182" A6NF36 17 57744495-57745299 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 202 "testis: 26.7" "Group enriched" "Detected in some" 96 "Early spermatids: 258.3;Late primary spermatocytes: 158.0;Late spermatids: 233.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA023446 Uncertain NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 55: Lymphoma - Immune response" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" "HPA023446: " CCDC183 "bA216L13.7, KIAA1984, MGC15438" ENSG00000213213 "Coiled-coil domain containing 183" Q5T5S1 9 136796338-136807741 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "testis: 23.3" "Group enriched" "Detected in some" 13 "Early spermatids: 189.2;Late primary spermatocytes: 84.5;Late spermatids: 165.9" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "plasmacytoid DC: 1.4" "Lineage enriched" "Detected in single" 5 "dendritic cells: 1.4" "Low cancer specificity" "Detected in some" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" HPA043812 Uncertain Approved "Nucleoplasm,Primary cilium tip,Cytosol,Mid piece" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 6: Non-specific - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" "Nucleoplasm, Cytosol" "Primary cilium tip, Mid piece" "HPA043812: " "unprognostic (7.82e-3)" "unprognostic (2.18e-1)" "unprognostic (3.01e-3)" "unprognostic (1.02e-1)" "unprognostic (1.47e-1)" "unprognostic (8.04e-3)" "unprognostic (2.72e-1)" "unprognostic (2.26e-3)" CCDC184 "C12orf68, LOC387856" ENSG00000177875 "Coiled-coil domain containing 184" Q52MB2 12 48183644-48185926 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.4" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 12.1;Decidual stromal cells: 52.0;Early spermatids: 69.6;Granulosa cells: 41.4;Late primary spermatocytes: 37.6;Late spermatids: 16.8;Other brain neurons: 13.6;Pancreatic islet cells: 15.3;Respiratory ciliated cells: 18.0" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 11.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bone cancer: 2.4;Neuroblastoma: 6.4;Rhabdoid: 8.0;Sarcoma: 2.3" "Colon - Colon enteroendocrine cells, Liver - Vascular endothelial cells, Spleen - Fibroblasts_2, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039947, HPA041715" Uncertain Approved Mitochondria,Cytosol No No "Cluster 10: Brain - Synaptic signal transduction" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 108: Fibroblasts - ECM organization" 9 "Mitochondria, Cytosol" "HPA039947: , HPA041715: " "unprognostic (2.11e-1)" "unprognostic (1.88e-3)" "unprognostic (2.01e-2)" "unprognostic (1.88e-3)" "unprognostic (2.02e-3)" "unprognostic (1.16e-2)" "unprognostic (1.57e-1)" "unprognostic (1.01e-1)" "unprognostic (8.00e-3)" "unprognostic (3.88e-1)" "unprognostic (1.50e-3)" "unprognostic (6.51e-2)" "unprognostic (2.53e-1)" CCDC185 "C1orf65, FLJ35728" ENSG00000178395 "Coiled-coil domain containing 185" Q8N715 1 223393415-223395465 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 338 "testis: 33.7" "Cell type enriched" "Detected in some" 10 "Early spermatids: 705.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 7: Liver cancer - Metabolism" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 36 CCDC186 "C10orf118, CCCP-1, FLJ10188, FLJ35301, golgin104" ENSG00000165813 "Coiled-coil domain containing 186" Q7Z3E2 10 114120862-114174232 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 410.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 49.4" "Group enriched" "Detected in all" 4 "dendritic cells: 49.4;granulocytes: 26.6" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014569, HPA018019" Approved Approved "Golgi apparatus" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 8: Pancreas - Proteolysis" "Cluster 5: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 29: Neutrophils - Innate immune cellular maintenance" "Golgi apparatus" "HPA014569: , HPA018019: " "unprognostic (2.54e-1)" "unprognostic (1.76e-2)" "unprognostic (1.78e-2)" "unprognostic (4.33e-1)" "unprognostic (1.13e-1)" "unprognostic (1.04e-1)" "unprognostic (1.08e-1)" "unprognostic (1.46e-3)" "unprognostic (8.44e-2)" "potential prognostic favorable (1.11e-7)" "unprognostic (1.09e-3)" "unprognostic (5.52e-2)" "unprognostic (2.01e-1)" "unprognostic (3.82e-3)" "unprognostic (2.84e-1)" "unprognostic (3.58e-2)" "unprognostic (3.41e-1)" "unprognostic (6.50e-2)" "potential prognostic unfavorable (2.60e-4)" "unprognostic (6.60e-2)" "unprognostic (4.68e-3)" "unprognostic (2.97e-1)" "unprognostic (2.86e-1)" "unprognostic (1.25e-1)" "unprognostic (1.94e-1)" "unprognostic (4.18e-2)" "unprognostic (3.00e-1)" "unprognostic (8.53e-2)" "unprognostic (2.80e-2)" CCDC187 MGC50722 ENSG00000260220 "Coiled-coil domain containing 187" A0A096LP49 9 136249973-136306901 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 7.1;pituitary gland: 6.7;testis: 28.3" "Cell type enriched" "Detected in some" 5 "Late spermatids: 913.2" "Group enriched" "Detected in some" 4 "central nervous system macrophage: 3.1;choroid plexus epithelial cell: 6.2;ependymal cell: 3.0" "Cancer enhanced" "Detected in some" "Thyroid Carcinoma (TCGA): 5.0" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 5.7" "Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "midbrain: 4.2" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" "unprognostic (1.08e-2)" "unprognostic (1.86e-1)" "unprognostic (4.97e-3)" CCDC188 ENSG00000234409 "Coiled-coil domain containing 188" H7C350 22 20148416-20151055 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "testis: 39.4" "Group enriched" "Detected in some" 30 "Early spermatids: 420.4;Late spermatids: 1494.0" "Cell type enhanced" "Detected in some" "ependymal cell: 1.6;mammillary body: 2.2;thalamic excitatory: 3.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 15 "plasmacytoid DC: 1.5" "Lineage enriched" "Detected in single" 15 "dendritic cells: 1.5" "Cancer enhanced" "Detected in some" "Neuroblastoma: 8.4" "Prostate - Endothelial cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA049901 Approved "Nucleoplasm,Nuclear bodies,Flagellar centriole" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" "Nuclear bodies" "Nucleoplasm, Flagellar centriole" "HPA049901: " "unprognostic (2.29e-1)" "unprognostic (3.64e-3)" "unprognostic (2.07e-2)" CCDC190 "C1orf110, MGC48998" ENSG00000185860 "Coiled-coil domain containing 190" Q86UF4 1 162824458-162868761 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "blood vessel: 2.6;esophagus: 2.5;lung: 1.5" "Cell type enriched" "Detected in some" 10 "Respiratory ciliated cells: 381.3" "Group enriched" "Detected in some" 5 "astrocyte: 30.8;ependymal cell: 41.6" "Cancer enhanced" "Detected in many" "Lung Squamous Cell Carcinoma (TCGA): 10.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Smooth muscle cells, Lung - Respiratory ciliated cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028579, HPA028584, HPA028592" Uncertain Approved "Actin filaments,Cytosol" NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 46: Brainstem - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" "Actin filaments, Cytosol" "HPA028579: , HPA028584: , HPA028592: " "unprognostic (4.72e-1)" "unprognostic (6.07e-2)" "unprognostic (1.96e-2)" "unprognostic (2.39e-2)" "unprognostic (1.46e-2)" "unprognostic (7.02e-3)" "unprognostic (5.40e-2)" "unprognostic (5.25e-2)" "unprognostic (1.22e-1)" "unprognostic (1.51e-1)" "unprognostic (2.06e-1)" "unprognostic (5.14e-1)" CCDC191 KIAA1407 ENSG00000163617 "Coiled-coil domain containing 191" Q8NCU4 3 113964137-114056594 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 173.3;Endometrial ciliated cells: 134.5;Ependymal cells: 268.5;Fallopian tube ciliated cells: 222.5;Respiratory ciliated cells: 264.4" "Cell type enhanced" "Detected in all" "ependymal cell: 289.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047833 Approved Approved Mitochondria NA NA "Cluster 34: B-cells - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 55: Lymphoma - Immune response" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 2 Mitochondria "HPA047833: " "unprognostic (2.90e-1)" "unprognostic (3.54e-1)" "unprognostic (6.45e-2)" "unprognostic (1.62e-2)" "unprognostic (9.58e-2)" "unprognostic (3.45e-1)" "unprognostic (3.11e-1)" "unprognostic (3.46e-2)" "unprognostic (3.24e-2)" "unprognostic (1.13e-1)" "potential prognostic favorable (1.34e-4)" "unprognostic (4.78e-2)" "unprognostic (2.54e-1)" "unprognostic (3.49e-2)" "unprognostic (2.77e-3)" "unprognostic (2.99e-1)" "unprognostic (8.40e-2)" "unprognostic (5.25e-2)" "unprognostic (3.19e-3)" "unprognostic (1.62e-1)" "potential prognostic favorable (5.24e-4)" "unprognostic (8.37e-2)" "unprognostic (2.03e-1)" "unprognostic (4.81e-2)" "unprognostic (1.17e-1)" "unprognostic (8.29e-2)" "unprognostic (6.10e-2)" CCDC192 LINC01183 ENSG00000230561 "Coiled-coil domain containing 192" P0DO97 5 127703361-127941507 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 14.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 93.7;Early spermatids: 310.9;Epicardial cells: 52.3;Late primary spermatocytes: 259.6;Late spermatids: 140.2;Leydig cells: 84.6;Undifferentiated spermatogonia: 51.8" "Cell type enhanced" "Detected in all" "fibroblast: 76.0" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Gallbladder cancer: 1.6" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 38: Sub-cortical - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" CCDC194 ENSG00000269720 "Coiled-coil domain containing 194" A0A1B0GVG4 19 17387196-17394196 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "ovary: 2.1" "Cell type enhanced" "Detected in some" "Adrenal cortex cells: 8.1;Adrenal medulla cells: 10.6;Granulosa cells: 10.5;Hematopoietic stem cells: 6.8;Late primary spermatocytes: 12.7;Leydig cells: 9.2;Medullary thymic epithelial cells: 12.0;Ovarian stromal cells: 23.6;Peritubular myoid cells: 7.7;Thymic myoid cells: 29.9" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 1.5;fibroblast: 1.0" "Cancer enriched" "Detected in single" 6 "Ovary Serous Cystadenocarcinoma (TCGA): 1.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.0" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 75: Ovary - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 94: Gonadal somatic cells - Mixed function" "unprognostic (1.04e-1)" "unprognostic (1.96e-1)" CCDC195 ENSG00000283428 "Coiled-coil domain containing 195" A0A1B0GUA6 2 224703764-224716365 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Colonocytes: 1.6;Early primary spermatocytes: 1.7;Endometrial glandular cells: 1.5;Endometrial stromal cells: 1.1;Enteric transient amplifying cells: 1.8;Enterocytes: 1.0;Foveolar cells: 1.0;Gonadotrophs: 3.0;Myosatellite cells: 2.6;Undifferentiated spermatogonia: 3.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Leukemia: 1.0;lymphoma: 3.9;Sarcoma: 3.9" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 11: Neuronal - Sensory perception" "Cluster 51: Secretory epithelial cells - Mixed function" "unprognostic (3.70e-2)" CCDC196 "C14orf53, LINC00238, NCRNA00238" ENSG00000196553 "Coiled-coil domain containing 196" A0A1B0GTZ2 14 66411704-66498677 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 21 "testis: 3.7" "Group enriched" "Detected in many" 15 "Early spermatids: 1450.2;Late spermatids: 5552.8" "Cell type enhanced" "Detected in all" "eccentric medium spiny neuron: 56.7" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" CCDC197 "C14orf48, LINC00521" ENSG00000175699 "Coiled-coil domain containing 197" 14 93987225-94008863 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 7 "testis: 7.8" "Cell type enriched" "Detected in some" 5 "Late spermatids: 568.9" "Cell type enriched" "Detected in single" 4 "lower rhombic lip: 2.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Gallbladder cancer: 1.2" "Heart muscle - Cardiomyocytes, Testis - Late spermatids" "Not detected" "Not detected" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 49: Hindbrain - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" CCDC198 "C14orf105, FLJ10650" ENSG00000100557 "Coiled-coil domain containing 198" Q9NVL8 14 57469300-57493867 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 25.8;kidney: 86.0;liver: 35.6;pancreas: 31.9" "Cell type enhanced" "Detected in some" "Cholangiocytes: 122.1;Distal convoluted tubule cells: 236.7;Epididymal efferent duct absorptive cells: 136.9;Epididymal efferent duct ciliated cells: 363.0;Fallopian tube ciliated cells: 173.9;Loop of henle epithelial cells: 229.7;Pancreatic duct cells: 145.9;Proximal tubule cells: 451.0;Renal collecting duct intercalated cells: 188.6;Renal collecting duct principal cells: 194.5;Renal connecting tubule cells: 319.1" "Cell type enhanced" "Detected in some" "astrocyte: 10.0;Bergmann glia: 6.2" "Group enriched" "Detected in many" 4 "Kidney Chromophobe (TCGA): 20.8;Kidney Renal Clear Cell Carcinoma (TCGA): 39.9;Kidney Renal Papillary Cell Carcinoma (TCGA): 82.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Bile duct cancer: 9.6;Kidney cancer: 17.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA029202 Uncertain Nucleoplasm,Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 72: Kidney - Transmembrane transport" "Cluster 6: Non-specific - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 88: Proximal tubular cells - Transmembrane transport" 16 Cytosol Nucleoplasm "HPA029202: " "unprognostic (2.09e-1)" "unprognostic (2.57e-1)" "unprognostic (4.20e-2)" "unprognostic (3.16e-2)" "potential prognostic favorable (1.77e-5)" "unprognostic (1.90e-3)" "unprognostic (1.59e-3)" "unprognostic (1.58e-3)" "unprognostic (1.35e-2)" "unprognostic (1.23e-1)" "unprognostic (1.25e-1)" "unprognostic (1.28e-1)" "unprognostic (1.40e-1)" "unprognostic (1.36e-1)" "unprognostic (8.36e-3)" CCDC200 "LINC00854, TMEM106A-AS1" ENSG00000236383 "Coiled-coil domain containing 200" A0A1B0GVQ3 17 43216941-43305397 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "testis: 42.1" "Cell type enriched" "Detected in many" 7 "Late spermatids: 3420.5" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 61.1;ependymal cell: 21.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 8.3;NK-cell: 7.2" "Group enriched" "Detected in many" 5 "granulocytes: 8.3;NK-cells: 7.2" "Low cancer specificity" "Detected in many" "Adrenal gland - Macrophages, Testis - Late spermatids" "Not detected" "Not detected" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 79: Testis - Spermatogenesis" "Cluster 25: Non-specific - Transcription" "Cluster 56: Non-specific - Sensory perception" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" "unprognostic (6.54e-3)" "unprognostic (1.90e-2)" "unprognostic (2.07e-2)" "unprognostic (4.17e-3)" "unprognostic (3.40e-3)" "unprognostic (1.35e-3)" "unprognostic (3.29e-2)" "unprognostic (2.11e-2)" "potential prognostic unfavorable (2.66e-5)" "unprognostic (2.21e-1)" "unprognostic (1.99e-1)" "unprognostic (1.85e-1)" "unprognostic (6.99e-2)" "unprognostic (3.20e-2)" "unprognostic (5.32e-3)" "unprognostic (1.89e-1)" "unprognostic (9.10e-3)" "unprognostic (8.45e-2)" "unprognostic (1.32e-1)" "unprognostic (7.51e-2)" "unprognostic (4.47e-2)" "unprognostic (1.40e-1)" "unprognostic (9.90e-2)" "unprognostic (2.12e-1)" "unprognostic (9.31e-2)" CCDC201 ENSG00000283247 "Coiled-coil domain containing 201" A0A1B0GTI1 7 45859994-45873082 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 8 "Oocytes: 41.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" NA NA "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 3: Rhabdoid - Membrane components" "Cluster 41: Oocytes - Oogenesis" CCDC22 "CXorf37, JM1" ENSG00000101997 "Coiled-coil domain containing 22" O60826 X 49235470-49250520 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport, Ubl conjugation pathway" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 46.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000229, HPA000888, HPA075980" Uncertain Approved Approved "Endoplasmic reticulum,Vesicles" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 36: Non-specific - mRNA processing" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 109 "Endoplasmic reticulum" Vesicles "HPA000229: , HPA000888: , HPA075980: " "unprognostic (2.47e-1)" "unprognostic (3.85e-3)" "unprognostic (8.62e-2)" "unprognostic (4.78e-2)" "unprognostic (2.24e-1)" "unprognostic (2.17e-1)" "unprognostic (2.29e-1)" "unprognostic (2.53e-2)" "unprognostic (6.17e-2)" "unprognostic (1.53e-1)" "unprognostic (3.95e-3)" "unprognostic (1.12e-1)" "unprognostic (1.83e-1)" "potential prognostic unfavorable (1.20e-5)" "unprognostic (4.53e-3)" "unprognostic (8.07e-3)" "unprognostic (1.01e-1)" "unprognostic (2.75e-1)" "unprognostic (5.32e-2)" "unprognostic (2.40e-1)" "unprognostic (3.98e-2)" "unprognostic (3.79e-2)" "unprognostic (3.17e-1)" "unprognostic (2.74e-2)" "unprognostic (5.39e-2)" "unprognostic (8.77e-2)" "unprognostic (4.19e-1)" "unprognostic (6.77e-2)" "unprognostic (1.77e-1)" "unprognostic (9.77e-2)" "unprognostic (7.96e-3)" CCDC24 MGC45441 ENSG00000159214 "Coiled-coil domain containing 24" Q8N4L8 1 43991359-43996528 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fallopian tube ciliated cells: 84.3;Late primary spermatocytes: 78.7;Respiratory ciliated cells: 96.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "eosinophil: 1.0;intermediate monocyte: 2.2;memory B-cell: 3.5;naive B-cell: 2.3;non-classical monocyte: 1.8" "Group enriched" "Detected in many" 5 "B-cells: 3.5;granulocytes: 1.0;monocytes: 2.2" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Skin - Eccrine sweat gland cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA035424, HPA061710" Uncertain Approved "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" 30 "Plasma membrane" "Nucleoli, Cytosol" "HPA035424: , HPA061710: " "unprognostic (1.10e-1)" "potential prognostic favorable (9.32e-4)" "unprognostic (1.87e-1)" "unprognostic (4.40e-2)" "unprognostic (1.87e-1)" "unprognostic (1.02e-2)" "unprognostic (1.51e-3)" "unprognostic (6.96e-2)" "unprognostic (1.04e-1)" "unprognostic (1.57e-1)" "unprognostic (3.02e-2)" "unprognostic (3.28e-2)" "unprognostic (1.09e-3)" "potential prognostic unfavorable (9.03e-4)" "unprognostic (2.22e-1)" "unprognostic (4.40e-2)" "unprognostic (1.53e-1)" "unprognostic (4.55e-2)" "unprognostic (3.01e-1)" "unprognostic (2.50e-1)" "unprognostic (5.77e-2)" "unprognostic (1.18e-2)" "unprognostic (1.92e-1)" "unprognostic (2.09e-1)" "unprognostic (2.05e-2)" "unprognostic (4.87e-2)" "unprognostic (2.30e-1)" "unprognostic (3.34e-2)" "unprognostic (2.41e-1)" "unprognostic (5.58e-2)" "unprognostic (1.34e-1)" CCDC25 FLJ10853 ENSG00000147419 "Coiled-coil domain containing 25" Q86WR0 8 27733316-27772653 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 233.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023256 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 76: Non-specific - Metabolism" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 40: Non-specific - Unknown function" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 4 "Nucleoplasm, Golgi apparatus" Cytosol "HPA023256: " "unprognostic (2.79e-2)" "unprognostic (1.57e-1)" "unprognostic (2.52e-1)" "unprognostic (1.17e-1)" "unprognostic (9.92e-3)" "unprognostic (4.05e-2)" "unprognostic (8.83e-2)" "unprognostic (1.61e-1)" "unprognostic (6.30e-2)" "unprognostic (7.87e-2)" "potential prognostic favorable (1.89e-7)" "unprognostic (2.14e-3)" "unprognostic (5.18e-2)" "unprognostic (2.67e-1)" "unprognostic (1.00e-1)" "unprognostic (2.47e-1)" "unprognostic (1.30e-1)" "unprognostic (4.94e-2)" "unprognostic (1.21e-1)" "unprognostic (2.95e-2)" "unprognostic (5.87e-3)" "unprognostic (1.45e-1)" "unprognostic (2.22e-1)" "unprognostic (5.40e-2)" "unprognostic (1.45e-2)" "unprognostic (1.69e-1)" "unprognostic (2.37e-1)" "unprognostic (1.55e-2)" "unprognostic (3.16e-1)" "unprognostic (2.91e-1)" "unprognostic (2.87e-1)" CCDC27 FLJ32825 ENSG00000162592 "Coiled-coil domain containing 27" Q2M243 1 3746460-3771645 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 44 "testis: 16.2" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 27.1;Early spermatids: 342.7;Late primary spermatocytes: 114.8;Late spermatids: 54.8;Oocytes: 92.1" "Cell type enhanced" "Detected in single" "choroid plexus epithelial cell: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Region enriched" "Detected in single" 12 "basal ganglia: 1.7" HPA044395 Approved Nucleoplasm,Cytosol NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 47: Leukemia - Hemostasis" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 1 Cytosol Nucleoplasm "HPA044395: " CCDC28A "C6orf80, CCRL1AP, DKFZp586D0623" ENSG00000024862 "Coiled-coil domain containing 28A" 6 138773769-138793319 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 185.7;Syncytiotrophoblasts: 138.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055125 Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 29: Neutrophils - Innate immune cellular maintenance" "Plasma membrane" Nucleoplasm "HPA055125: " "unprognostic (5.02e-2)" "unprognostic (1.79e-2)" "unprognostic (1.99e-1)" "unprognostic (5.23e-2)" "unprognostic (2.90e-1)" "unprognostic (1.04e-1)" "unprognostic (2.08e-2)" "unprognostic (8.13e-2)" "unprognostic (3.55e-2)" "unprognostic (1.20e-1)" "potential prognostic favorable (1.75e-7)" "unprognostic (3.19e-2)" "potential prognostic favorable (7.19e-4)" "unprognostic (1.87e-1)" "unprognostic (1.80e-1)" "unprognostic (1.99e-3)" "unprognostic (6.38e-2)" "unprognostic (4.09e-2)" "unprognostic (7.26e-2)" "unprognostic (6.40e-3)" "unprognostic (3.73e-2)" "potential prognostic favorable (6.81e-4)" "unprognostic (3.58e-1)" "unprognostic (9.68e-2)" "unprognostic (5.16e-3)" "unprognostic (7.77e-3)" "unprognostic (4.04e-1)" "unprognostic (3.91e-1)" "unprognostic (1.51e-1)" "unprognostic (1.62e-2)" "unprognostic (2.55e-1)" CCDC28B "MGC1203, RP4-622L5.5" ENSG00000160050 "Coiled-coil domain containing 28B" Q9BUN5 1 32200595-32205453 "Disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Bardet-Biedl syndrome, Ciliopathy, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "skeletal muscle: 211.2;tongue: 69.8" "Cell type enhanced" "Detected in many" "Late spermatids: 55.3;Megakaryocyte progenitors: 54.8;Megakaryocytes: 309.1;Tuft cells: 103.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 83.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "lymphoma: 69.5" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Testis - Sertoli cells" "Region enriched" "Detected in all" 4 "cerebellum: 124.9" "Low region specificity" "Detected in all" HPA028589 Uncertain NA NA "Cluster 24: Non-specific - Transcription" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 55: Lymphoma - Immune response" "Cluster 47: Platelets - Hemostasis" 9 "HPA028589: " "unprognostic (7.74e-2)" "potential prognostic favorable (9.05e-4)" "unprognostic (1.49e-1)" "unprognostic (5.98e-2)" "unprognostic (3.71e-1)" "unprognostic (7.08e-3)" "unprognostic (3.19e-3)" "unprognostic (2.54e-3)" "unprognostic (1.17e-1)" "unprognostic (3.30e-1)" "potential prognostic unfavorable (4.71e-4)" "unprognostic (4.87e-2)" "unprognostic (1.59e-2)" "unprognostic (4.00e-3)" "unprognostic (5.33e-2)" "unprognostic (1.74e-1)" "unprognostic (1.11e-2)" "unprognostic (1.80e-1)" "unprognostic (2.48e-1)" "unprognostic (2.20e-2)" "unprognostic (1.32e-2)" "potential prognostic favorable (2.32e-4)" "unprognostic (1.77e-1)" "unprognostic (6.44e-2)" "unprognostic (6.17e-2)" "unprognostic (6.38e-2)" "unprognostic (6.06e-2)" "unprognostic (9.39e-3)" "unprognostic (1.51e-1)" "unprognostic (2.31e-2)" "unprognostic (1.50e-1)" CCDC3 DKFZp761F241 ENSG00000151468 "Coiled-coil domain containing 3" Q9BQI4 10 12896625-13099652 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 309.8" "Cell type enhanced" "Detected in many" "Adipocytes: 282.3;Brain excitatory neurons: 109.0;Brain inhibitory neurons: 99.7;Medullary thymic epithelial cells: 367.2;Oocytes: 105.9;Pericytes: 135.4;Vascular endothelial cells: 96.7;Vascular smooth muscle cells: 331.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 21.9" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Smooth muscle cells, Breast - Endothelial cells, Liver - Hepatic stellate cells, Lung - Smooth muscle cells, Minor Salivary Gland - Endothelial cells, Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 27.4" HPA062425 Uncertain Nucleoplasm,Cytosol "Secreted to blood" "No annotated function" NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 51: Neurons - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 62: Smooth muscle cells - Muscle contraction" 2 Cytosol Nucleoplasm "HPA062425: " "unprognostic (1.16e-1)" "unprognostic (1.67e-1)" "unprognostic (2.65e-1)" "unprognostic (1.75e-1)" "unprognostic (5.23e-2)" "unprognostic (3.24e-1)" "unprognostic (1.02e-1)" "unprognostic (2.84e-1)" "unprognostic (1.71e-1)" "unprognostic (7.19e-2)" "unprognostic (4.86e-2)" "potential prognostic favorable (9.32e-4)" "unprognostic (1.50e-3)" "unprognostic (8.89e-2)" "unprognostic (2.12e-2)" "unprognostic (8.09e-2)" "unprognostic (1.55e-1)" "unprognostic (5.37e-2)" "unprognostic (1.51e-1)" "unprognostic (2.09e-2)" "unprognostic (1.05e-2)" "unprognostic (1.29e-3)" "unprognostic (4.29e-3)" "unprognostic (1.86e-2)" "unprognostic (1.63e-1)" "unprognostic (5.01e-3)" "unprognostic (5.17e-2)" "unprognostic (6.78e-3)" "unprognostic (2.77e-2)" "unprognostic (2.12e-1)" "unprognostic (3.62e-1)" CCDC30 "FLJ20972, LOC728621, PFD6L" ENSG00000186409 "Coiled-coil domain containing 30" Q5VVM6 1 42463221-42657190 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 9.6" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 773.6;Endometrial ciliated cells: 314.6;Ependymal cells: 1267.3;Fallopian tube ciliated cells: 341.2;Lactotrophs: 301.4;Proximal tubule cells: 298.1;Respiratory ciliated cells: 702.0;Somatotrophs: 296.5;Thyrotrophs: 257.8" "Group enriched" "Detected in all" 4 "choroid plexus epithelial cell: 555.3;ependymal cell: 1297.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036344, HPA036345" Approved NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" "HPA036344: , HPA036345: " "unprognostic (1.67e-1)" "unprognostic (1.74e-1)" "unprognostic (2.90e-1)" "unprognostic (1.06e-1)" "unprognostic (1.04e-1)" "unprognostic (3.27e-1)" "unprognostic (7.32e-2)" "unprognostic (5.82e-2)" "unprognostic (2.32e-2)" "unprognostic (3.01e-3)" "unprognostic (2.95e-3)" "unprognostic (6.07e-3)" "unprognostic (3.31e-1)" "unprognostic (1.89e-1)" "unprognostic (2.64e-1)" "unprognostic (1.51e-1)" "unprognostic (1.14e-1)" "unprognostic (2.57e-3)" "unprognostic (8.69e-3)" "unprognostic (1.11e-1)" "unprognostic (1.64e-2)" "unprognostic (1.18e-2)" "unprognostic (2.53e-2)" "unprognostic (3.12e-1)" "unprognostic (1.29e-2)" "unprognostic (3.93e-2)" CCDC32 "C15orf57, MGC20481" ENSG00000128891 "Coiled-coil domain containing 32" Q9BV29 15 40528683-40565054 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" Ciliopathy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041360, HPA041688" Uncertain Approved "Plasma membrane,Microtubules,Primary cilium,Centrosome,Basal body" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 6 "Plasma membrane" "Microtubules, Primary cilium, Centrosome, Basal body" "HPA041360: , HPA041688: " "unprognostic (5.68e-3)" "unprognostic (2.12e-2)" "unprognostic (9.72e-2)" "unprognostic (6.67e-2)" "unprognostic (9.87e-2)" "unprognostic (1.56e-2)" "unprognostic (5.48e-2)" "potential prognostic unfavorable (1.80e-4)" "unprognostic (2.59e-1)" "validated prognostic favorable (3.26e-4)" "validated prognostic favorable (1.15e-4)" "unprognostic (7.80e-2)" "unprognostic (2.64e-2)" "unprognostic (1.52e-2)" "unprognostic (2.96e-3)" "unprognostic (1.96e-1)" "unprognostic (1.23e-1)" "unprognostic (6.71e-2)" "unprognostic (9.84e-2)" "unprognostic (1.78e-2)" "unprognostic (6.64e-3)" "unprognostic (2.17e-2)" "unprognostic (2.31e-2)" "unprognostic (1.95e-1)" "unprognostic (6.14e-2)" "unprognostic (6.61e-2)" "unprognostic (1.91e-1)" "unprognostic (2.72e-1)" "unprognostic (2.93e-2)" CCDC33 "CT61, FLJ32855" ENSG00000140481 "Coiled-coil domain containing 33" Q8N5R6 15 74202705-74336472 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "fallopian tube: 17.9;testis: 19.3" "Cell type enhanced" "Detected in some" "Early spermatids: 38.6;Endometrial ciliated cells: 28.4;Ependymal cells: 50.0;Epididymal efferent duct ciliated cells: 13.9;Fallopian tube ciliated cells: 50.3;Late primary spermatocytes: 11.5;Late spermatids: 56.1;Papillary tip epithelial cells: 13.5;Respiratory ciliated cells: 42.4;Retinal pigment epithelial cells: 51.2" "Cell type enriched" "Detected in some" 34 "ependymal cell: 62.5" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 3.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Neuroblastoma: 2.0" "Adrenal gland - Adrenal cortex cells, Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" "Region enhanced" "Detected in many" "midbrain: 9.6" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" 20 "unprognostic (4.88e-2)" "unprognostic (1.76e-1)" "unprognostic (1.47e-1)" "unprognostic (8.21e-2)" CCDC34 "L15, NY-REN-41, RAMA3" ENSG00000109881 "Coiled-coil domain containing 34" Q96HJ3 11 27330827-27363234 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 48.3" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 271.9;Early primary spermatocytes: 211.5;Early spermatids: 324.2;Endometrial ciliated cells: 150.8;Epididymal efferent duct ciliated cells: 168.7;Late primary spermatocytes: 606.6;Oocytes: 152.0;Undifferentiated spermatogonia: 156.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Outer root sheath cells, Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037574 Uncertain Approved "Nuclear membrane,Nucleoli fibrillar center,Calyx,Connecting piece,Mid piece,Principal piece,End piece" NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 24: Neurons - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 27: Non-specific - Cell proliferation" "Nuclear membrane, Nucleoli fibrillar center, Calyx, Mid piece" "Connecting piece, Principal piece, End piece" "HPA037574: " "unprognostic (2.41e-2)" "unprognostic (7.12e-2)" "unprognostic (2.69e-1)" "unprognostic (2.74e-2)" "unprognostic (2.19e-1)" "unprognostic (4.75e-2)" "unprognostic (9.60e-3)" "unprognostic (3.40e-1)" "unprognostic (1.50e-1)" "unprognostic (1.06e-2)" "potential prognostic unfavorable (6.53e-4)" "unprognostic (3.52e-2)" "potential prognostic unfavorable (1.66e-4)" "validated prognostic unfavorable (2.31e-8)" "validated prognostic unfavorable (1.34e-5)" "potential prognostic unfavorable (2.83e-5)" "unprognostic (8.76e-3)" "unprognostic (7.03e-3)" "unprognostic (5.22e-2)" "unprognostic (5.62e-3)" "unprognostic (8.55e-2)" "unprognostic (1.71e-2)" "unprognostic (6.92e-3)" "unprognostic (8.39e-2)" "unprognostic (1.79e-2)" "unprognostic (1.27e-1)" "unprognostic (2.29e-2)" "unprognostic (1.03e-1)" "unprognostic (3.49e-1)" "unprognostic (3.42e-3)" "unprognostic (7.02e-2)" CCDC38 FLJ40089 ENSG00000165972 "Coiled-coil domain containing 38" Q502W7 12 95867048-95942635 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 15.7" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 36.5;Early spermatids: 86.2;Late primary spermatocytes: 253.3;Late spermatids: 46.1" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 56: Non-specific - Sensory perception" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" "unprognostic (7.01e-3)" CCDC39 "CFAP59, CILD14, DKFZp434A128, FAP59" ENSG00000284862 "Coiled-coil domain containing 39" Q9UFE4 3 180602858-180684942 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 20.2;retina: 20.2;skin 1: 19.1" "Group enriched" "Detected in many" 4 "Adipocytes: 113.6;Cardiomyocytes: 282.7;Epicardial cells: 222.9" "Cell type enhanced" "Detected in all" "ependymal cell: 50.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035363, HPA035364" Enhanced Uncertain "Nucleoplasm,Centrosome,Basal body,Acrosome" NA NA "Cluster 40: Non-specific - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 56: Non-specific - Sensory perception" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 2 "Nucleoplasm, Centrosome, Basal body, Acrosome" "HPA035363: , HPA035364: " "unprognostic (8.67e-3)" "unprognostic (2.06e-1)" "unprognostic (7.96e-2)" "unprognostic (4.98e-2)" "unprognostic (8.61e-2)" "unprognostic (1.08e-1)" "unprognostic (9.77e-2)" "potential prognostic favorable (3.46e-4)" "unprognostic (3.03e-2)" "unprognostic (4.77e-2)" "unprognostic (2.41e-1)" "unprognostic (6.26e-2)" "unprognostic (1.72e-1)" "unprognostic (9.37e-2)" "unprognostic (2.51e-1)" "potential prognostic favorable (6.68e-6)" "unprognostic (1.29e-1)" "unprognostic (2.65e-1)" "unprognostic (5.45e-3)" "unprognostic (2.84e-3)" "unprognostic (1.10e-1)" "unprognostic (9.70e-2)" "unprognostic (9.97e-2)" "unprognostic (3.18e-1)" "unprognostic (7.43e-3)" "unprognostic (1.24e-1)" CCDC40 "CFAP172, CILD15, FAP172, FLJ20753, FLJ32021, KIAA1640" ENSG00000141519 "Coiled-coil domain containing 40" Q4G0X9 17 80036632-80100613 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 13.7;fallopian tube: 14.0" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 238.4;Endometrial ciliated cells: 190.4;Ependymal cells: 298.7;Epididymal efferent duct ciliated cells: 153.2;Fallopian tube ciliated cells: 212.5;Respiratory ciliated cells: 301.7" "Group enriched" "Detected in many" 5 "choroid plexus epithelial cell: 181.2;ependymal cell: 301.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA022974 Enhanced Approved "Microtubules,Cytokinetic bridge,Primary cilium,Cytosol,Mid piece" Yes NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" 4 "Microtubules, Primary cilium, Cytosol" "Cytokinetic bridge, Mid piece" "HPA022974: " "unprognostic (7.37e-3)" "unprognostic (2.60e-2)" "unprognostic (4.52e-2)" "unprognostic (5.11e-3)" "unprognostic (6.03e-2)" "unprognostic (1.48e-1)" "unprognostic (9.98e-3)" "potential prognostic unfavorable (4.93e-4)" "unprognostic (1.62e-2)" "unprognostic (2.48e-3)" "unprognostic (2.39e-1)" "unprognostic (1.56e-2)" "unprognostic (3.11e-3)" "unprognostic (4.76e-2)" "unprognostic (1.92e-2)" "unprognostic (1.85e-1)" "unprognostic (5.00e-3)" "unprognostic (1.26e-1)" "unprognostic (4.18e-2)" "potential prognostic favorable (5.33e-4)" "potential prognostic favorable (9.62e-4)" "unprognostic (6.14e-3)" "unprognostic (2.17e-2)" "unprognostic (2.24e-2)" "unprognostic (9.84e-2)" "unprognostic (2.16e-1)" "unprognostic (5.81e-2)" "unprognostic (1.11e-1)" "unprognostic (1.34e-3)" "unprognostic (1.36e-2)" CCDC42 "CCDC42A, FLJ32734" ENSG00000161973 "Coiled-coil domain containing 42" Q96M95 17 8729935-8745219 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 64 "testis: 90.2" "Cell type enriched" "Detected in some" 11 "Late primary spermatocytes: 623.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 6: Leukemia - Signal transduction" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 3 CCDC43 FLJ31795 ENSG00000180329 "Coiled-coil domain containing 43" Q96MW1 17 44673069-44689779 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 68.8" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023078, HPA023391" Enhanced Approved Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 34: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 17: Non-specific - RNA processing" 17 Cytosol "HPA023078: , HPA023391: " "unprognostic (5.37e-2)" "unprognostic (9.41e-3)" "unprognostic (1.62e-1)" "unprognostic (4.19e-2)" "unprognostic (6.73e-2)" "unprognostic (1.57e-1)" "unprognostic (8.13e-2)" "unprognostic (1.50e-2)" "unprognostic (1.22e-3)" "potential prognostic unfavorable (6.09e-5)" "potential prognostic favorable (1.20e-5)" "unprognostic (2.71e-2)" "unprognostic (1.60e-1)" "potential prognostic unfavorable (2.82e-4)" "unprognostic (1.20e-3)" "unprognostic (1.60e-2)" "unprognostic (8.65e-3)" "unprognostic (1.48e-1)" "unprognostic (3.97e-2)" "unprognostic (1.18e-1)" "unprognostic (9.29e-2)" "potential prognostic unfavorable (3.44e-4)" "unprognostic (7.15e-3)" "unprognostic (3.33e-1)" "unprognostic (2.12e-2)" "unprognostic (3.98e-2)" "unprognostic (3.23e-3)" "unprognostic (2.22e-1)" "unprognostic (2.52e-1)" "unprognostic (2.35e-1)" "unprognostic (2.03e-2)" CCDC47 GK001 ENSG00000108588 "Coiled-coil domain containing 47" Q96A33 17 63745255-63776351 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Chaperone "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029674, HPA072573, HPA075958" Approved Enhanced "Endoplasmic reticulum" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 76: Non-specific - Metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 27: Breast cancer - Unknown function" "Cluster 17: Non-specific - RNA processing" 127 "Endoplasmic reticulum" "HPA029674: , HPA072573: , HPA075958: " "unprognostic (4.50e-1)" "unprognostic (7.38e-3)" "unprognostic (5.67e-2)" "unprognostic (1.12e-2)" "unprognostic (1.61e-3)" "unprognostic (7.76e-2)" "unprognostic (1.89e-1)" "unprognostic (9.62e-3)" "unprognostic (2.19e-2)" "potential prognostic unfavorable (4.17e-6)" "potential prognostic favorable (2.03e-5)" "unprognostic (1.17e-1)" "unprognostic (8.63e-2)" "validated prognostic unfavorable (7.81e-4)" "validated prognostic unfavorable (4.41e-4)" "unprognostic (8.86e-2)" "unprognostic (4.76e-3)" "unprognostic (1.43e-1)" "unprognostic (3.39e-2)" "unprognostic (1.58e-1)" "unprognostic (7.00e-2)" "unprognostic (3.68e-2)" "unprognostic (1.47e-1)" "unprognostic (1.65e-1)" "unprognostic (5.67e-2)" "unprognostic (5.60e-2)" "unprognostic (3.52e-1)" "unprognostic (2.36e-1)" "unprognostic (1.55e-1)" "unprognostic (1.33e-1)" "unprognostic (3.03e-1)" CCDC50 "C3orf6, DFNA44, Ymer" ENSG00000152492 "Coiled-coil domain containing 50" Q8IVM0 3 191329085-191398659 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte progenitor cells: 419.9;pDCs: 1021.9" "Cell type enhanced" "Detected in all" "oligodendrocyte precursor cell: 498.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "plasmacytoid DC: 631.6" "Lineage enriched" "Detected in all" 5 "dendritic cells: 631.6" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001336 Approved Supported "Basal body,Cytosol" NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 55: Lymphoma - Immune response" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 19 Cytosol "Basal body" "HPA001336: " "unprognostic (5.87e-3)" "unprognostic (1.94e-1)" "unprognostic (3.91e-1)" "unprognostic (1.76e-2)" "unprognostic (2.07e-1)" "unprognostic (1.51e-1)" "unprognostic (1.11e-1)" "unprognostic (1.97e-2)" "unprognostic (1.47e-1)" "unprognostic (9.14e-2)" "potential prognostic favorable (2.12e-5)" "unprognostic (9.31e-2)" "unprognostic (1.33e-1)" "potential prognostic unfavorable (7.18e-8)" "unprognostic (1.07e-1)" "potential prognostic unfavorable (4.28e-4)" "unprognostic (1.46e-1)" "unprognostic (1.34e-1)" "unprognostic (1.63e-1)" "unprognostic (2.65e-1)" "potential prognostic unfavorable (4.37e-4)" "potential prognostic unfavorable (2.31e-4)" "unprognostic (1.49e-2)" "unprognostic (1.36e-1)" "unprognostic (2.58e-1)" "unprognostic (3.54e-2)" "unprognostic (2.63e-2)" "unprognostic (4.36e-2)" "unprognostic (2.39e-1)" "unprognostic (1.51e-1)" "unprognostic (4.17e-1)" CCDC51 FLJ12436 ENSG00000164051 "Coiled-coil domain containing 51" Q96ER9 3 48432164-48440456 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "choroid plexus: 60.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 46.8;Migrating cytotrophoblasts: 54.2;Retinal pigment epithelial cells: 81.0" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 18.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010980, HPA011408" Supported Supported Nucleoplasm,Centrosome,Mitochondria NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 97: Non-specific - Cellular respiration" 6 "Nucleoplasm, Mitochondria" Centrosome "HPA010980: , HPA011408: " "unprognostic (1.41e-1)" "unprognostic (1.88e-1)" "unprognostic (5.95e-2)" "unprognostic (2.09e-1)" "unprognostic (8.45e-2)" "unprognostic (1.60e-1)" "unprognostic (1.89e-1)" "unprognostic (1.41e-1)" "unprognostic (1.50e-1)" "unprognostic (1.96e-2)" "unprognostic (2.57e-2)" "unprognostic (5.30e-1)" "unprognostic (1.19e-3)" "unprognostic (1.56e-3)" "unprognostic (3.83e-3)" "unprognostic (3.49e-3)" "potential prognostic unfavorable (3.22e-4)" "potential prognostic favorable (4.31e-4)" "unprognostic (3.90e-2)" "unprognostic (1.15e-1)" "unprognostic (2.46e-1)" "unprognostic (2.23e-2)" "unprognostic (8.61e-2)" "unprognostic (1.14e-2)" "unprognostic (4.23e-2)" "unprognostic (2.67e-3)" "unprognostic (1.26e-1)" "unprognostic (8.06e-3)" "unprognostic (1.95e-1)" "unprognostic (3.23e-2)" "unprognostic (4.06e-2)" CCDC54 "FLJ25362, NYD-SP17, SP17" ENSG00000138483 "Coiled-coil domain containing 54" Q8NEL0 3 107377439-107378635 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 127 "testis: 116.0" "Group enriched" "Detected in some" 5 "Early spermatids: 1586.0;Late spermatids: 5192.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 11: White matter - Signal transduction" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" CCDC57 "FLJ00130, FLJ23754" ENSG00000176155 "Coiled-coil domain containing 57" Q2TAC2 17 82101460-82212878 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in all" 5 "Late spermatids: 1233.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "naive CD4 T-cell: 3.0;naive CD8 T-cell: 7.1" "Lineage enriched" "Detected in many" 6 "T-cells: 7.1" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA023315, HPA023326, HPA023342, HPA023344" Approved Approved "Microtubules,Centriolar satellite,Cytosol" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 64: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 56: Non-specific - Sensory perception" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 35 Microtubules "Centriolar satellite, Cytosol" "HPA023315: , HPA023326: , HPA023342: , HPA023344: " "unprognostic (1.64e-1)" "unprognostic (2.47e-3)" "unprognostic (1.03e-1)" "unprognostic (1.30e-2)" "unprognostic (1.77e-1)" "unprognostic (9.65e-3)" "unprognostic (7.33e-2)" "unprognostic (1.87e-1)" "unprognostic (1.59e-3)" "unprognostic (5.68e-3)" "potential prognostic unfavorable (5.86e-6)" "unprognostic (2.44e-2)" "unprognostic (1.09e-2)" "unprognostic (4.14e-2)" "unprognostic (4.24e-2)" "unprognostic (3.13e-1)" "unprognostic (1.50e-1)" "unprognostic (7.56e-2)" "unprognostic (2.33e-3)" "unprognostic (4.28e-2)" "unprognostic (3.97e-2)" "potential prognostic favorable (3.80e-4)" "unprognostic (6.09e-3)" "unprognostic (5.19e-2)" "unprognostic (5.05e-2)" "potential prognostic favorable (1.44e-7)" "unprognostic (3.63e-2)" "unprognostic (2.16e-1)" "unprognostic (7.00e-2)" "unprognostic (1.31e-1)" "unprognostic (2.30e-1)" CCDC59 "BR22, HSPC128, TAP26" ENSG00000133773 "Coiled-coil domain containing 59" Q9P031 12 82223681-82358805 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 309.7;Oocytes: 331.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038555 Approved Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Plasma membrane" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 15: Non-specific - Protein processing" 23 "Nucleoli, Nucleoli rim" "Nucleoplasm, Plasma membrane" "HPA038555: " "unprognostic (4.01e-2)" "unprognostic (1.44e-1)" "unprognostic (1.55e-1)" "unprognostic (8.28e-2)" "unprognostic (2.32e-1)" "unprognostic (1.43e-1)" "unprognostic (1.40e-1)" "unprognostic (3.82e-2)" "unprognostic (1.66e-3)" "unprognostic (9.29e-2)" "unprognostic (1.40e-3)" "unprognostic (6.27e-2)" "potential prognostic unfavorable (9.95e-4)" "validated prognostic unfavorable (8.99e-4)" "validated prognostic unfavorable (6.09e-4)" "unprognostic (1.47e-3)" "unprognostic (6.17e-2)" "unprognostic (1.93e-1)" "unprognostic (2.23e-1)" "unprognostic (1.67e-1)" "unprognostic (8.50e-3)" "unprognostic (1.86e-1)" "unprognostic (1.14e-3)" "unprognostic (1.23e-2)" "unprognostic (1.67e-2)" "unprognostic (1.01e-1)" "unprognostic (1.12e-1)" "unprognostic (2.24e-1)" "unprognostic (2.14e-1)" "unprognostic (1.93e-1)" "unprognostic (8.05e-2)" CCDC6 "D10S170, H4, PTC, TPC, TST1" ENSG00000108091 "Coiled-coil domain containing 6" Q16204 10 59788747-59906556 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 376.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019049, HPA019051" Enhanced Supported Cytosol No No 6200 "Cluster 23: B-cells - Immunoglobulins" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 52: Non-specific - Mitochondria" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 71 Cytosol "HPA019049: , HPA019051: " "unprognostic (5.88e-2)" "unprognostic (1.95e-2)" "unprognostic (1.16e-1)" "unprognostic (1.46e-1)" "unprognostic (1.54e-1)" "unprognostic (2.88e-2)" "unprognostic (3.56e-2)" "unprognostic (3.45e-3)" "unprognostic (1.36e-2)" "unprognostic (2.95e-2)" "potential prognostic favorable (3.51e-6)" "unprognostic (2.87e-1)" "unprognostic (1.39e-1)" "potential prognostic unfavorable (9.10e-4)" "unprognostic (2.72e-3)" "unprognostic (4.24e-2)" "unprognostic (4.39e-2)" "unprognostic (3.31e-2)" "unprognostic (1.03e-1)" "unprognostic (1.03e-1)" "unprognostic (9.13e-3)" "potential prognostic unfavorable (3.32e-4)" "unprognostic (2.84e-1)" "unprognostic (5.78e-2)" "unprognostic (9.75e-2)" "unprognostic (4.65e-1)" "unprognostic (1.58e-1)" "unprognostic (3.81e-1)" "unprognostic (4.37e-1)" "unprognostic (4.74e-2)" "unprognostic (7.20e-2)" CCDC60 MGC39827 ENSG00000183273 "Coiled-coil domain containing 60" Q8IWA6 12 119334712-119541040 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 30.9;fallopian tube: 17.2;testis: 11.0" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 96.5;Choroid plexus epithelial cells: 296.6;Cone photoreceptor cells: 178.0;Early spermatids: 201.4;Endometrial ciliated cells: 116.8;Ependymal cells: 474.1;Epididymal efferent duct ciliated cells: 138.9;Fallopian tube ciliated cells: 203.0;Late primary spermatocytes: 126.0;Late spermatids: 100.0;Prostatic hillock cells: 93.2;Respiratory ciliated cells: 317.2;Retinal pigment epithelial cells: 140.7" "Group enriched" "Detected in many" 21 "choroid plexus epithelial cell: 215.4;ependymal cell: 472.8" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 7.4" "Region enriched" "Detected in all" 4 "choroid plexus: 50.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "testis cancer: 1.4" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 1: Neuronal - Visual perception" "Cluster 34: Ciliated cells - Cilia assembly & function" 1 "unprognostic (1.53e-1)" "unprognostic (3.44e-3)" "unprognostic (1.07e-2)" "unprognostic (6.54e-2)" "unprognostic (3.86e-2)" "unprognostic (9.62e-2)" "unprognostic (2.48e-2)" "unprognostic (9.40e-2)" "unprognostic (2.10e-1)" "unprognostic (2.68e-2)" "unprognostic (2.20e-1)" "unprognostic (5.21e-2)" "unprognostic (4.09e-1)" CCDC61 "hVFL3, VFL3" ENSG00000104983 "Coiled-coil domain containing 61" Q9Y6R9 19 45995461-46021318 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "basophil: 6.5" "Lineage enriched" "Detected in many" 5 "granulocytes: 6.5" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040325, HPA061548" Uncertain Approved Nucleoplasm NA NA "Cluster 11: T-cells - Unknown function" "Cluster 21: Testis - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 3 Nucleoplasm "HPA040325: , HPA061548: " "unprognostic (1.44e-1)" "unprognostic (1.95e-2)" "unprognostic (1.29e-2)" "unprognostic (9.82e-2)" "unprognostic (1.20e-1)" "unprognostic (3.87e-1)" "unprognostic (1.10e-1)" "unprognostic (1.44e-1)" "unprognostic (2.96e-3)" "unprognostic (3.42e-1)" "unprognostic (2.10e-1)" "unprognostic (2.93e-3)" "potential prognostic favorable (8.67e-4)" "unprognostic (1.15e-2)" "unprognostic (4.06e-1)" "unprognostic (1.66e-1)" "unprognostic (1.26e-1)" "unprognostic (3.12e-1)" "unprognostic (6.66e-2)" "unprognostic (4.83e-2)" "unprognostic (9.80e-2)" "unprognostic (1.99e-1)" "unprognostic (1.03e-1)" "unprognostic (3.06e-1)" "unprognostic (3.39e-2)" "unprognostic (1.71e-1)" "unprognostic (2.04e-1)" "unprognostic (1.58e-1)" "unprognostic (2.02e-1)" "unprognostic (1.47e-1)" "unprognostic (1.98e-2)" CCDC62 "CT109, ERAP75, FLJ40344, TSP-NY" ENSG00000130783 "Coiled-coil domain containing 62" Q6P9F0 12 122774526-122827528 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 48 "testis: 65.5" "Group enriched" "Detected in many" 4 "Early spermatids: 203.0;Late primary spermatocytes: 609.9" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA039021, HPA058741" Approved Uncertain "Nucleoplasm,Plasma membrane" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 34: Non-specific - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 1 "Plasma membrane" Nucleoplasm "HPA039021: , HPA058741: " "unprognostic (1.52e-3)" CCDC63 "FLJ35843, ODA5" ENSG00000173093 "Coiled-coil domain containing 63" Q8NA47 12 110846769-110907535 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "testis: 16.6" "Group enriched" "Detected in some" 12 "Early spermatids: 395.4;Late primary spermatocytes: 227.1;Late spermatids: 389.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" HPA043927 Approved "Nucleoplasm,Cell Junctions,Principal piece" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 27: Breast cancer - Unknown function" "Cluster 46: Skeletal myocytes - Muscle structure & formation" "Nucleoplasm, Principal piece" "Cell Junctions" "HPA043927: " CCDC65 "CFAP250, CILD27, DRC2, FAP250, FLJ35732, NYD-SP28" ENSG00000139537 "Coiled-coil domain containing 65" Q8IXS2 12 48904110-48931840 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 18.3;fallopian tube: 25.0;testis: 34.8" "Cell type enhanced" "Detected in many" "Early spermatids: 111.3;Endometrial ciliated cells: 144.8;Epicardial cells: 272.9;Fallopian tube ciliated cells: 184.7;Late primary spermatocytes: 291.5;Respiratory ciliated cells: 189.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "gdT-cell: 8.8;MAIT T-cell: 9.1;memory CD4 T-cell: 7.5;memory CD8 T-cell: 7.3;naive CD4 T-cell: 4.6;naive CD8 T-cell: 6.2;T-reg: 4.9" "Lineage enriched" "Detected in single" 11 "T-cells: 9.1" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038520, HPA057573" Uncertain Approved "Vesicles,Primary cilium transition zone,Centriolar satellite,Mid piece,Principal piece,Annulus" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 56: Non-specific - Sensory perception" "Cluster 107: Ciliated cells - Cilia assembly & function" 2 "Vesicles, Primary cilium transition zone, Centriolar satellite" "Mid piece, Principal piece, Annulus" "HPA038520: , HPA057573: " "unprognostic (1.78e-1)" "unprognostic (2.03e-1)" "unprognostic (2.30e-2)" "unprognostic (2.05e-3)" "potential prognostic unfavorable (7.78e-5)" "unprognostic (9.55e-2)" "unprognostic (1.03e-1)" "potential prognostic favorable (1.00e-4)" "unprognostic (1.54e-2)" "unprognostic (2.70e-2)" "unprognostic (2.60e-1)" "unprognostic (2.63e-1)" "unprognostic (6.92e-2)" "unprognostic (1.78e-1)" "unprognostic (1.91e-1)" "unprognostic (1.40e-2)" "unprognostic (1.02e-1)" "unprognostic (1.37e-1)" "unprognostic (2.59e-1)" "unprognostic (8.87e-2)" "unprognostic (1.45e-3)" "unprognostic (6.07e-2)" CCDC66 DKFZp686C0433 ENSG00000180376 "Coiled-coil domain containing 66" A2RUB6 3 56557161-56621837 "Predicted intracellular proteins" "Cell cycle, Cell division, Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044185, HPA051937" Approved Supported "Vesicles,Plasma membrane,Cell Junctions,Midbody ring,Primary cilium,Centriolar satellite,Cytosol,Perinuclear theca,End piece" Yes No "Cluster 5: Non-specific - Cell proliferation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 9: T-cells - Adaptive immunity: Regulation" 4 "Primary cilium, Centriolar satellite, Perinuclear theca" "Vesicles, Plasma membrane, Cell Junctions, Midbody ring, Cytosol, End piece" "HPA044185: , HPA051937: " "unprognostic (4.04e-1)" "unprognostic (2.43e-1)" "unprognostic (2.82e-2)" "unprognostic (2.12e-2)" "unprognostic (1.10e-1)" "unprognostic (1.16e-1)" "unprognostic (3.46e-1)" "unprognostic (1.10e-1)" "unprognostic (3.44e-2)" "unprognostic (3.78e-2)" "unprognostic (8.34e-3)" "unprognostic (1.82e-2)" "unprognostic (3.26e-2)" "unprognostic (4.65e-2)" "unprognostic (1.97e-1)" "unprognostic (6.77e-2)" "unprognostic (1.60e-1)" "unprognostic (4.37e-2)" "unprognostic (4.70e-2)" "unprognostic (2.23e-1)" "unprognostic (1.92e-1)" "unprognostic (2.72e-1)" "unprognostic (3.49e-2)" "unprognostic (6.65e-2)" "unprognostic (1.47e-2)" "unprognostic (6.35e-3)" "unprognostic (1.07e-1)" "unprognostic (1.84e-1)" "unprognostic (1.43e-1)" "unprognostic (4.96e-2)" "unprognostic (1.08e-1)" CCDC68 SE57-1 ENSG00000166510 "Coiled-coil domain containing 68" Q9H2F9 18 54901509-54959461 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 23.3;placenta: 30.5" "Cell type enhanced" "Detected in many" "Colonocytes: 116.1;Early spermatids: 97.4;Enterocytes: 114.2;Epididymal clear cells: 81.7;Foveolar cells: 95.4;Goblet cells: 73.0;Prostatic glandular cells: 81.6;Salivary ionocytes: 118.3;Sertoli cells: 163.0;Somatotrophs: 166.9;Vascular endothelial cells: 95.1" "Group enriched" "Detected in many" 5 "endothelial cell: 136.6;mammillary body: 42.7" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 12.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Pituitary gland - Somatotropes, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA040865, HPA048197" Supported Approved "Golgi apparatus,Cytosol" No NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 5 "Golgi apparatus" Cytosol "HPA040865: , HPA048197: " "unprognostic (1.22e-1)" "unprognostic (3.74e-2)" "unprognostic (1.32e-1)" "unprognostic (2.48e-3)" "unprognostic (5.59e-3)" "unprognostic (1.71e-1)" "unprognostic (7.90e-2)" "unprognostic (3.52e-1)" "unprognostic (1.60e-2)" "potential prognostic favorable (1.91e-4)" "unprognostic (9.70e-2)" "unprognostic (2.60e-2)" "unprognostic (1.73e-2)" "unprognostic (1.61e-1)" "unprognostic (2.18e-2)" "unprognostic (1.67e-1)" "potential prognostic unfavorable (6.83e-4)" "unprognostic (2.01e-2)" "unprognostic (1.74e-3)" "unprognostic (3.25e-2)" "unprognostic (2.87e-1)" "unprognostic (1.78e-2)" "unprognostic (9.47e-2)" "unprognostic (9.81e-3)" "unprognostic (4.88e-1)" "unprognostic (3.22e-1)" CCDC69 "DKFZP434C171, FLJ13705" ENSG00000198624 "Coiled-coil domain containing 69" A6NI79 5 151181052-151224093 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 330.8" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 136.9;Fallopian tube ciliated cells: 112.3;Monocyte progenitors: 118.0;monocytes: 155.3;Neutrophils: 348.3;NK-cells: 120.7;pDCs: 200.1;Plasma cells: 146.8;Respiratory ciliated cells: 106.6;Thymocytes: 122.0" "Cell type enhanced" "Detected in many" "endothelial cell: 44.3;ependymal cell: 46.9;leukocyte: 97.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 9 "Leukemia: 41.0;lymphoma: 129.6;Myeloma: 60.0" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Pituitary gland - Gonadotropes, Prostate - Smooth muscle cells" "Region enhanced" "Detected in some" "cerebellum: 4.8" "Low region specificity" "Detected in all" "HPA043648, HPA052896" Uncertain Approved "Golgi apparatus,Plasma membrane,Actin filaments" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" "Plasma membrane" "Golgi apparatus, Actin filaments" "HPA043648: , HPA052896: " "unprognostic (1.93e-1)" "unprognostic (1.13e-2)" "unprognostic (1.30e-1)" "unprognostic (4.51e-2)" "unprognostic (1.92e-2)" "unprognostic (8.60e-2)" "unprognostic (6.99e-2)" "unprognostic (2.74e-1)" "unprognostic (5.11e-2)" "unprognostic (2.55e-1)" "potential prognostic favorable (8.50e-6)" "unprognostic (1.41e-2)" "unprognostic (1.60e-1)" "unprognostic (8.86e-2)" "unprognostic (3.06e-3)" "unprognostic (5.87e-3)" "unprognostic (1.95e-2)" "potential prognostic unfavorable (7.51e-5)" "unprognostic (3.42e-1)" "unprognostic (7.65e-2)" "unprognostic (4.08e-1)" "unprognostic (4.62e-2)" "unprognostic (4.31e-2)" "unprognostic (3.12e-2)" "unprognostic (8.63e-2)" "unprognostic (1.24e-2)" "unprognostic (3.60e-2)" "unprognostic (3.72e-2)" "unprognostic (4.57e-2)" "unprognostic (1.59e-1)" "unprognostic (1.19e-2)" CCDC7 "BIOT2, C10orf68, FLJ13031, FLJ32762" ENSG00000216937 "Coiled-coil domain containing 7" Q96M83 10 32446140-32882874 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 29 "testis: 74.0" "Cell type enhanced" "Detected in many" "Early spermatids: 690.7;Late primary spermatocytes: 696.6;Late spermatids: 2169.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in single" HPA075536 Approved "Nucleoli,Mitotic spindle,Cytosol" Yes No "Cluster 1: T-cells - Unknown function" "Cluster 57: Testis - Spermatogenesis" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 1 Nucleoli "Mitotic spindle, Cytosol" "HPA075536: " "unprognostic (2.70e-1)" "unprognostic (2.05e-1)" "unprognostic (3.30e-2)" "unprognostic (1.27e-3)" "unprognostic (2.55e-1)" "unprognostic (5.66e-2)" "unprognostic (2.56e-1)" "unprognostic (3.51e-3)" "unprognostic (3.12e-3)" "unprognostic (8.41e-2)" CCDC70 "DKFZP434K1172, FLJ25853" ENSG00000123171 "Coiled-coil domain containing 70" Q6NSX1 13 51861969-51866232 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1186 "testis: 126.8" "Cell type enriched" "Detected in some" 4 "Late spermatids: 4602.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA079644 Enhanced NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 29: Forebrain - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 13 "HPA079644: " CCDC71 FLJ12800 ENSG00000177352 "Coiled-coil domain containing 71" Q8IV32 3 49162535-49166331 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 28.9;Epididymal principal cells: 32.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 4.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047547 Uncertain Approved "Nuclear membrane" No No "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 75: Ovary - Mixed function" "Cluster 46: Brainstem - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 4 "Nuclear membrane" "HPA047547: " "unprognostic (5.66e-2)" "unprognostic (8.61e-2)" "unprognostic (9.47e-2)" "unprognostic (6.68e-3)" "unprognostic (8.42e-3)" "unprognostic (6.71e-3)" "unprognostic (9.85e-2)" "unprognostic (1.73e-2)" "unprognostic (1.08e-1)" "unprognostic (2.83e-2)" "potential prognostic favorable (1.05e-4)" "unprognostic (2.93e-2)" "potential prognostic favorable (9.90e-4)" "unprognostic (1.68e-3)" "unprognostic (1.33e-1)" "unprognostic (7.30e-3)" "unprognostic (1.91e-2)" "unprognostic (3.37e-1)" "unprognostic (2.52e-1)" "unprognostic (1.36e-1)" "unprognostic (1.59e-1)" "unprognostic (4.86e-2)" "unprognostic (2.13e-1)" "unprognostic (2.28e-1)" "unprognostic (6.04e-3)" "unprognostic (4.09e-1)" "unprognostic (3.74e-1)" "unprognostic (2.58e-1)" "unprognostic (1.33e-1)" "unprognostic (2.78e-1)" "unprognostic (9.30e-3)" CCDC71L "C7orf74, FLJ36031" ENSG00000253276 "Coiled-coil domain containing 71 like" Q8N9Z2 7 106654360-106661158 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 1.3;Fibroblasts: 1.1;Loop of henle epithelial cells: 8.6;Papillary tip epithelial cells: 4.6;Podocytes: 5.2;Proximal tubule cells: 2.1;Renal collecting duct intercalated cells: 2.1;Renal collecting duct principal cells: 4.3;Renal connecting tubule cells: 1.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067925 Approved Approved "Golgi apparatus,Actin filaments,Cytosol" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 105: Non-specific - Mixed function" 3 "Golgi apparatus, Actin filaments" Cytosol "HPA067925: " "unprognostic (1.42e-1)" "unprognostic (9.72e-2)" "potential prognostic unfavorable (1.07e-4)" "unprognostic (2.35e-1)" "unprognostic (8.87e-2)" "unprognostic (1.83e-2)" "unprognostic (2.01e-2)" "potential prognostic unfavorable (5.83e-4)" "unprognostic (8.40e-3)" "unprognostic (1.04e-2)" "potential prognostic unfavorable (5.78e-4)" "unprognostic (1.03e-1)" "unprognostic (4.94e-1)" "unprognostic (4.21e-2)" "unprognostic (1.16e-2)" "unprognostic (8.35e-2)" "unprognostic (2.31e-1)" "unprognostic (3.95e-2)" "unprognostic (2.53e-1)" "unprognostic (8.98e-3)" "unprognostic (1.04e-1)" "unprognostic (1.97e-1)" "unprognostic (7.26e-2)" "unprognostic (2.61e-2)" "unprognostic (1.68e-1)" "unprognostic (8.17e-2)" "unprognostic (3.17e-2)" "unprognostic (5.51e-2)" "unprognostic (2.93e-2)" CCDC73 NY-SAR-79 ENSG00000186714 "Coiled-coil domain containing 73" Q6ZRK6 11 32602721-32794662 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "testis: 3.5" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 134.3;Early primary spermatocytes: 440.2;Endometrial ciliated cells: 54.3;Oocytes: 55.3;Undifferentiated spermatogonia: 76.3" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Prostate Adenocarcinoma (TCGA): 2.2;Uterine Corpus Endometrial Carcinoma (TCGA): 5.4" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "Myeloma: 2.2" "Liver - Hepatocytes, Testis - Spermatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038668, HPA038669" Uncertain NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 37: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 3: Early primary spermatocytes - Early meiosis" "HPA038668: , HPA038669: " "unprognostic (2.12e-2)" "potential prognostic unfavorable (2.49e-4)" "unprognostic (1.77e-2)" "unprognostic (2.86e-1)" "unprognostic (1.20e-1)" CCDC74A FLJ40345 ENSG00000163040 "Coiled-coil domain containing 74A" Q96AQ1 2 131527675-131533666 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 62.7;testis: 70.6" "Cell type enhanced" "Detected in many" "Early spermatids: 407.2;Endometrial ciliated cells: 83.4;Epididymal efferent duct ciliated cells: 203.1;Fallopian tube ciliated cells: 175.7;Late primary spermatocytes: 396.8;Late spermatids: 413.8;Respiratory ciliated cells: 202.0" "Cell type enhanced" "Detected in many" "ependymal cell: 45.4" "Cancer enhanced" "Detected in all" "Breast Invasive Carcinoma (TCGA): 59.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Stomach - Fibroblasts, Testis - Early spermatids, Thyroid gland - Fibroblasts" HPA046284 Approved "Nucleoplasm,Centrosome,Basal body,Cytosol" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 11: Neuronal - Sensory perception" "Cluster 107: Ciliated cells - Cilia assembly & function" 2 "Centrosome, Basal body" "Nucleoplasm, Cytosol" "HPA046284: " "unprognostic (2.26e-1)" "unprognostic (5.38e-3)" "unprognostic (3.04e-2)" "unprognostic (2.02e-3)" "unprognostic (1.16e-2)" "unprognostic (1.09e-2)" "potential prognostic unfavorable (4.20e-4)" "unprognostic (5.04e-2)" "unprognostic (2.96e-1)" "potential prognostic unfavorable (4.18e-4)" "potential prognostic unfavorable (6.41e-6)" "unprognostic (2.41e-2)" "unprognostic (9.88e-3)" "unprognostic (5.40e-3)" "unprognostic (9.34e-2)" "unprognostic (7.29e-3)" "unprognostic (1.05e-2)" "unprognostic (1.71e-2)" "unprognostic (2.07e-1)" "unprognostic (4.99e-2)" "unprognostic (7.55e-2)" "unprognostic (1.42e-1)" "unprognostic (5.54e-2)" "unprognostic (1.51e-1)" "unprognostic (1.25e-1)" "unprognostic (5.42e-3)" "unprognostic (5.80e-2)" "unprognostic (9.00e-3)" "unprognostic (1.15e-3)" "unprognostic (6.22e-2)" "unprognostic (3.01e-1)" CCDC74B DKFZp434E2321 ENSG00000152076 "Coiled-coil domain containing 74B" Q96LY2 2 130139287-130145134 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 51.4" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 49.0;Early primary spermatocytes: 60.8;Early spermatids: 304.3;Epididymal efferent duct ciliated cells: 114.2;Fallopian tube ciliated cells: 115.2;Late primary spermatocytes: 351.0;Late spermatids: 177.2;Respiratory ciliated cells: 121.5" "Cell type enriched" "Detected in many" 7 "ependymal cell: 51.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 19.8" "Lung - Respiratory ciliated cells, Testis - Early spermatids" HPA046284 Approved "Nucleoplasm,Centrosome,Basal body,Cytosol" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 107: Ciliated cells - Cilia assembly & function" 1 "Centrosome, Basal body" "Nucleoplasm, Cytosol" "HPA046284: " "unprognostic (1.65e-3)" "unprognostic (3.53e-3)" "unprognostic (2.39e-1)" "unprognostic (1.10e-2)" "unprognostic (1.45e-1)" "unprognostic (4.13e-2)" "unprognostic (8.37e-2)" "unprognostic (3.25e-3)" "unprognostic (1.54e-1)" "unprognostic (2.48e-1)" "unprognostic (4.82e-2)" "unprognostic (2.86e-1)" "unprognostic (5.61e-2)" "unprognostic (7.40e-2)" "unprognostic (6.97e-3)" "unprognostic (7.64e-3)" "unprognostic (3.84e-1)" "unprognostic (5.94e-2)" "potential prognostic unfavorable (8.02e-4)" "unprognostic (9.16e-2)" CCDC77 MGC13183 ENSG00000120647 "Coiled-coil domain containing 77" Q9BR77 12 389273-442642 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 94.9" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 28.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038854 Approved Approved "Nuclear membrane" NA Yes "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 39: Testis - Nuclear processes" "Cluster 11: White matter - Signal transduction" "Cluster 38: Non-specific - Transcription" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 4 "Nuclear membrane" "HPA038854: " "unprognostic (7.37e-3)" "unprognostic (2.65e-1)" "unprognostic (3.67e-1)" "unprognostic (2.21e-1)" "unprognostic (1.09e-2)" "unprognostic (1.57e-1)" "unprognostic (5.92e-2)" "unprognostic (3.89e-2)" "unprognostic (1.33e-1)" "unprognostic (1.44e-1)" "unprognostic (3.16e-2)" "unprognostic (1.88e-2)" "unprognostic (2.59e-1)" "potential prognostic unfavorable (1.46e-7)" "unprognostic (3.06e-3)" "unprognostic (2.19e-2)" "unprognostic (8.47e-2)" "unprognostic (6.83e-3)" "unprognostic (2.90e-1)" "unprognostic (1.06e-1)" "unprognostic (3.49e-1)" "unprognostic (1.07e-1)" "potential prognostic unfavorable (4.38e-4)" "unprognostic (2.74e-1)" "unprognostic (3.35e-3)" "unprognostic (3.21e-2)" "unprognostic (3.20e-3)" "unprognostic (1.95e-1)" "unprognostic (1.83e-1)" "unprognostic (4.71e-2)" "unprognostic (6.38e-2)" CCDC78 "C16orf25, FLJ34512" ENSG00000162004 "Coiled-coil domain containing 78" A2IDD5 16 722582-726954 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.1;fallopian tube: 28.2" "Group enriched" "Detected in some" 29 "Endometrial ciliated cells: 210.5;Ependymal cells: 131.7;Epididymal efferent duct ciliated cells: 338.3;Fallopian tube ciliated cells: 318.6;Respiratory ciliated cells: 426.0" "Cell type enriched" "Detected in many" 7 "ependymal cell: 140.4" "Cancer enriched" "Detected in many" 4 "Uterine Corpus Endometrial Carcinoma (TCGA): 17.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal medulla cells, Lung - Respiratory ciliated cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 107: Ciliated cells - Cilia assembly & function" "unprognostic (2.13e-2)" "unprognostic (1.13e-1)" "unprognostic (5.88e-2)" "unprognostic (1.86e-3)" "unprognostic (3.12e-2)" "unprognostic (2.20e-1)" "unprognostic (1.60e-1)" "unprognostic (3.33e-2)" "unprognostic (1.28e-2)" "unprognostic (5.16e-2)" "unprognostic (1.64e-1)" "unprognostic (3.10e-2)" "unprognostic (7.16e-2)" "unprognostic (2.51e-1)" "unprognostic (1.08e-1)" "unprognostic (1.05e-1)" "unprognostic (9.11e-2)" "unprognostic (9.03e-3)" "unprognostic (5.65e-2)" "unprognostic (1.34e-1)" "unprognostic (1.60e-2)" "unprognostic (4.31e-2)" "unprognostic (1.38e-2)" CCDC8 "3M3, DKFZp564K0322, PPP1R20" ENSG00000169515 "Coiled-coil domain containing 8" Q9H0W5 19 46410329-46413564 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Dwarfism "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 35.3" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 48.2;Decidual stromal cells: 40.4;Ependymal cells: 28.4;Epididymal efferent duct ciliated cells: 39.0;Fallopian tube ciliated cells: 40.4;Granulosa cells: 28.4;Leydig cells: 54.4;Medullary thymic epithelial cells: 33.6;Ovarian stromal cells: 34.8;Peritubular myoid cells: 56.8;Thymic myoid cells: 40.8" "Cell type enhanced" "Detected in some" "ependymal cell: 33.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 43.0" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041993 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 46: Brainstem - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 94: Gonadal somatic cells - Mixed function" 40 "Plasma membrane, Cytosol" Nucleoplasm "HPA041993: " "unprognostic (1.07e-1)" "unprognostic (1.01e-2)" "unprognostic (2.29e-1)" "unprognostic (3.15e-1)" "unprognostic (6.79e-3)" "unprognostic (1.79e-1)" "validated prognostic unfavorable (8.50e-4)" "validated prognostic unfavorable (1.99e-7)" "unprognostic (2.71e-1)" "unprognostic (6.18e-2)" "potential prognostic favorable (7.54e-4)" "unprognostic (4.19e-3)" "unprognostic (3.44e-1)" "unprognostic (1.07e-1)" "unprognostic (1.98e-1)" "unprognostic (1.85e-2)" "unprognostic (4.07e-1)" "unprognostic (1.37e-1)" "unprognostic (3.24e-1)" "unprognostic (5.36e-2)" "unprognostic (1.79e-1)" "unprognostic (3.09e-2)" "unprognostic (1.44e-1)" "unprognostic (2.87e-2)" "unprognostic (1.88e-2)" "unprognostic (8.10e-3)" "unprognostic (3.52e-1)" "unprognostic (6.51e-2)" "unprognostic (5.87e-3)" CCDC80 "CL2, DRO1, LINC01279, SSG1, TCONS_00006930, URB" ENSG00000091986 "Coiled-coil domain containing 80" Q76M96 3 112596797-112649530 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 626.9;Epididymal basal cells: 216.1;Fibro-adipogenic progenitors: 370.1;Fibroblasts: 1048.8;Late spermatids: 544.8;Mesothelial cells: 636.4" "Cell type enhanced" "Detected in many" "astrocyte: 50.5;Bergmann glia: 101.1;deep-layer near-projecting: 53.2;fibroblast: 52.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Adrenal gland - Fibroblasts, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblasts_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblasts_1, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Testis - Late spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002266 Approved "Secreted to extracellular matrix" "No annotated function" NA NA 590000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 21: Non-specific - Metabolism" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" "HPA002266: " "unprognostic (3.94e-2)" "unprognostic (6.99e-2)" "unprognostic (1.10e-1)" "unprognostic (3.02e-1)" "unprognostic (1.39e-2)" "unprognostic (1.41e-1)" "unprognostic (5.29e-2)" "unprognostic (2.40e-1)" "unprognostic (2.13e-1)" "unprognostic (2.52e-1)" "unprognostic (1.61e-3)" "unprognostic (1.14e-2)" "potential prognostic unfavorable (1.28e-4)" "unprognostic (1.62e-1)" "unprognostic (8.33e-3)" "unprognostic (3.63e-1)" "unprognostic (7.37e-2)" "unprognostic (8.29e-2)" "unprognostic (2.75e-1)" "potential prognostic unfavorable (9.11e-4)" "unprognostic (2.14e-2)" "unprognostic (1.47e-1)" "unprognostic (7.79e-2)" "unprognostic (9.66e-2)" "unprognostic (2.96e-2)" "unprognostic (3.82e-2)" "unprognostic (4.16e-3)" "unprognostic (9.39e-3)" "unprognostic (2.41e-1)" "unprognostic (3.18e-1)" "unprognostic (3.54e-1)" CCDC81 "FLJ16339, FLJ23514" ENSG00000149201 "Coiled-coil domain containing 81" Q6ZN84 11 86374736-86423109 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 15.8;fallopian tube: 25.8" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 51.6;Endometrial ciliated cells: 115.8;Ependymal cells: 198.4;Epididymal efferent duct ciliated cells: 42.4;Extravillous trophoblasts: 40.8;Fallopian tube ciliated cells: 139.0;Late primary spermatocytes: 55.3;Migrating cytotrophoblasts: 46.2;Pituitary stem cells: 113.0;Respiratory ciliated cells: 123.7" "Cell type enriched" "Detected in all" 4 "ependymal cell: 223.7" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 2.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "testis cancer: 1.9" "Adipose subcutaneous - Smooth muscle cells, Lung - Respiratory ciliated cells, Skeletal muscle - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA040745 Approved "Plasma membrane,Basal body" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 34: Ciliated cells - Cilia assembly & function" 1 "Plasma membrane, Basal body" "HPA040745: " "unprognostic (1.64e-2)" "unprognostic (3.57e-1)" "unprognostic (1.46e-1)" "potential prognostic favorable (1.95e-4)" "unprognostic (1.35e-2)" "unprognostic (4.98e-1)" CCDC82 FLJ23518 ENSG00000149231 "Coiled-coil domain containing 82" Q8N4S0 11 96349241-96389956 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 500.4;Late primary spermatocytes: 484.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038704, HPA070631" Uncertain Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 24: Non-specific - Unknown function" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 6 Nucleoplasm "Nuclear bodies, Cytosol" "HPA038704: , HPA070631: " "unprognostic (1.11e-1)" "unprognostic (3.44e-1)" "unprognostic (7.76e-2)" "unprognostic (3.83e-2)" "unprognostic (5.71e-2)" "unprognostic (1.37e-1)" "unprognostic (8.87e-2)" "unprognostic (1.86e-1)" "unprognostic (8.95e-2)" "potential prognostic unfavorable (3.19e-4)" "unprognostic (7.67e-3)" "potential prognostic favorable (8.48e-4)" "unprognostic (2.50e-2)" "unprognostic (1.14e-2)" "unprognostic (3.38e-1)" "unprognostic (2.59e-1)" "unprognostic (1.33e-3)" "unprognostic (2.69e-1)" "unprognostic (8.28e-2)" "unprognostic (3.82e-2)" "unprognostic (1.98e-1)" "unprognostic (4.95e-3)" "potential prognostic unfavorable (4.26e-4)" "unprognostic (1.32e-1)" "unprognostic (1.11e-1)" "unprognostic (3.64e-2)" "unprognostic (1.61e-2)" "unprognostic (6.24e-2)" "unprognostic (4.00e-1)" "unprognostic (1.49e-1)" "unprognostic (1.73e-1)" CCDC83 "CT148, FLJ42119, KP-CoT-23, MGC34732" ENSG00000150676 "Coiled-coil domain containing 83" Q8IWF9 11 85855101-85920021 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 333 "testis: 33.2" "Group enriched" "Detected in many" 16 "Early spermatids: 180.4;Late primary spermatocytes: 449.4;Late spermatids: 316.2" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA039882, HPA075087" Approved Nucleoplasm,Vesicles NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 27: Breast cancer - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 1 Nucleoplasm Vesicles "HPA039882: , HPA075087: " CCDC85A KIAA1912 ENSG00000055813 "Coiled-coil domain containing 85A" Q96PX6 2 56183990-56386172 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 11.8;brain: 11.9" "Cell type enhanced" "Detected in some" "Astrocytes: 69.9;Brain excitatory neurons: 236.0;Brain inhibitory neurons: 191.8;Choroid plexus epithelial cells: 102.6;Oligodendrocyte progenitor cells: 48.3;Other brain neurons: 181.8;Vascular endothelial cells: 28.9" "Cell type enhanced" "Detected in all" "hippocampal dentate gyrus: 937.3" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 4.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Heart muscle - Endothelial cells, Lung - Alveolar cells type 1, Minor Salivary Gland - Endothelial cells, Prostate - Fibroblasts, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043106, HPA057020" Uncertain NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 109: Neurons - Neuronal signaling" 4 "HPA043106: , HPA057020: " "unprognostic (3.47e-2)" "unprognostic (1.49e-1)" "unprognostic (1.36e-1)" "potential prognostic favorable (2.50e-4)" "unprognostic (2.53e-1)" "validated prognostic favorable (1.66e-6)" "validated prognostic favorable (4.02e-4)" "unprognostic (2.86e-2)" "unprognostic (1.74e-1)" "unprognostic (8.83e-3)" "unprognostic (2.90e-1)" "unprognostic (9.34e-2)" "unprognostic (1.21e-1)" "unprognostic (2.44e-2)" CCDC85B DIPA ENSG00000175602 "Coiled-coil domain containing 85B" Q15834 11 65890673-65891635 "Predicted intracellular proteins" "Differentiation, Growth regulation, Host-virus interaction, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 367.2" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 417.3;Megakaryocytes: 358.5;Platelets: 542.2;Vascular endothelial cells: 332.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054415 Uncertain NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 31 "HPA054415: " "unprognostic (2.70e-2)" "unprognostic (1.15e-2)" "unprognostic (3.39e-2)" "unprognostic (3.24e-3)" "unprognostic (5.11e-2)" "unprognostic (7.94e-2)" "unprognostic (2.71e-1)" "unprognostic (2.95e-1)" "unprognostic (3.00e-2)" "unprognostic (2.97e-1)" "unprognostic (2.55e-2)" "unprognostic (1.89e-1)" "unprognostic (6.72e-3)" "unprognostic (1.78e-2)" "unprognostic (1.04e-2)" "unprognostic (2.41e-3)" "unprognostic (2.70e-2)" "unprognostic (1.43e-1)" "unprognostic (5.13e-2)" "unprognostic (8.63e-2)" "unprognostic (4.84e-2)" "unprognostic (5.98e-2)" "unprognostic (3.44e-1)" "unprognostic (1.42e-1)" "unprognostic (1.97e-1)" "unprognostic (2.68e-2)" "unprognostic (9.37e-3)" "unprognostic (1.23e-1)" "unprognostic (7.88e-2)" "unprognostic (8.49e-2)" "unprognostic (3.68e-1)" CCDC85C ENSG00000205476 "Coiled-coil domain containing 85C" A6NKD9 14 99500190-99604207 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 73.0" "Cell type enhanced" "Detected in many" "Epicardial cells: 163.7;Esophageal apical cells: 101.3;Podocytes: 127.0;Rod photoreceptor cells: 94.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058346 Uncertain Approved "Nuclear speckles,Cell Junctions" NA No "Cluster 27: Cerebellum - Synaptic function" "Cluster 15: Non-specific - Transcription" "Cluster 72: Neuronal - Signal transduction" "Cluster 51: Secretory epithelial cells - Mixed function" 13 "Nuclear speckles, Cell Junctions" "HPA058346: " "unprognostic (1.94e-1)" "unprognostic (2.27e-2)" "unprognostic (3.55e-2)" "unprognostic (1.24e-2)" "unprognostic (6.66e-2)" "unprognostic (1.24e-1)" "unprognostic (7.00e-2)" "unprognostic (3.94e-2)" "unprognostic (1.87e-1)" "unprognostic (1.56e-1)" "potential prognostic favorable (2.42e-6)" "unprognostic (4.99e-3)" "unprognostic (2.62e-1)" "unprognostic (1.12e-3)" "unprognostic (5.62e-2)" "potential prognostic unfavorable (3.28e-4)" "unprognostic (3.02e-1)" "unprognostic (2.90e-1)" "unprognostic (1.19e-1)" "unprognostic (2.69e-2)" "unprognostic (1.46e-1)" "unprognostic (1.81e-1)" "unprognostic (7.56e-2)" "potential prognostic unfavorable (7.22e-4)" "unprognostic (3.11e-2)" "unprognostic (8.08e-3)" "unprognostic (1.18e-2)" "unprognostic (5.86e-2)" "unprognostic (2.56e-1)" "unprognostic (2.20e-2)" "unprognostic (2.55e-1)" CCDC86 "cyclon, MGC2574" ENSG00000110104 "Coiled-coil domain containing 86" Q9H6F5 11 60842113-60851081 "Essential proteins, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 8 "parathyroid gland: 355.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 30.9;Esophageal basal cells: 40.9;Late primary spermatocytes: 127.5;Oocytes: 41.4" "Cell type enhanced" "Detected in many" "fibroblast: 13.2;pericyte: 13.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041117, HPA041540" Enhanced Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 13: Non-specific - Mitochondria" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 27: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 22 "Nucleoli, Nucleoli rim, Mitotic chromosome" Nucleoplasm "HPA041117: , HPA041540: " "unprognostic (1.75e-1)" "unprognostic (1.86e-1)" "unprognostic (1.31e-1)" "unprognostic (1.42e-1)" "unprognostic (1.42e-2)" "unprognostic (1.32e-1)" "unprognostic (2.19e-1)" "unprognostic (4.30e-2)" "potential prognostic unfavorable (9.36e-6)" "unprognostic (1.79e-3)" "unprognostic (6.41e-2)" "unprognostic (1.56e-1)" "unprognostic (4.95e-2)" "validated prognostic unfavorable (1.44e-6)" "validated prognostic unfavorable (1.00e-5)" "validated prognostic unfavorable (9.37e-4)" "validated prognostic unfavorable (3.61e-4)" "unprognostic (4.08e-1)" "unprognostic (2.03e-2)" "unprognostic (5.46e-3)" "unprognostic (8.42e-2)" "unprognostic (2.37e-2)" "unprognostic (3.58e-2)" "unprognostic (1.23e-1)" "unprognostic (4.66e-2)" "unprognostic (2.42e-1)" "unprognostic (2.43e-1)" "unprognostic (1.49e-2)" "unprognostic (4.95e-1)" "unprognostic (4.37e-2)" "unprognostic (5.76e-2)" CCDC87 FLJ10786 ENSG00000182791 "Coiled-coil domain containing 87" Q9NVE4 11 66590176-66593063 "Predicted intracellular proteins" "Differentiation, Fertilization, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 13.3" "Group enriched" "Detected in some" 4 "Early spermatids: 25.6;Late primary spermatocytes: 44.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA079508 Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 7 "Nucleoli, Cytosol" Nucleoplasm "HPA079508: " "unprognostic (6.21e-2)" "unprognostic (1.98e-1)" "unprognostic (1.90e-1)" CCDC88A "APE, FLJ10392, GIV, GRDN, HkRP1, KIAA1212" ENSG00000115355 "Coiled-coil domain containing 88A" Q3V6T2 2 55287842-55419895 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Neurogenesis" "Guanine-nucleotide releasing factor" "Epilepsy, Intellectual disability, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 65.7" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 518.3;Early spermatids: 952.9;Late primary spermatocytes: 485.1;Late spermatids: 1269.6;Monocyte progenitors: 528.8;Oligodendrocytes: 952.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 6.1;classical monocyte: 7.1;intermediate monocyte: 7.0;myeloid DC: 11.3;non-classical monocyte: 6.8;plasmacytoid DC: 23.7" "Group enriched" "Detected in all" 6 "dendritic cells: 23.7;granulocytes: 6.1;monocytes: 7.1" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038101, HPA038102" Enhanced Supported "Nucleoplasm,Plasma membrane,Centrosome,Basal body" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 80: Oligodendrocytes - Myelination" 21 "Nucleoplasm, Centrosome, Basal body" "Plasma membrane" "HPA038101: , HPA038102: " "unprognostic (2.43e-2)" "unprognostic (9.29e-2)" "unprognostic (2.49e-2)" "unprognostic (6.88e-2)" "unprognostic (1.91e-1)" "unprognostic (5.13e-3)" "unprognostic (1.89e-2)" "unprognostic (2.09e-3)" "unprognostic (1.43e-1)" "unprognostic (1.63e-2)" "unprognostic (1.41e-2)" "unprognostic (1.80e-1)" "unprognostic (6.73e-3)" "validated prognostic unfavorable (1.60e-5)" "validated prognostic unfavorable (4.05e-4)" "unprognostic (6.99e-3)" "unprognostic (7.66e-2)" "unprognostic (7.26e-2)" "unprognostic (1.39e-1)" "unprognostic (3.59e-1)" "unprognostic (3.41e-1)" "unprognostic (5.54e-2)" "potential prognostic unfavorable (3.26e-4)" "unprognostic (1.14e-1)" "unprognostic (7.66e-2)" "unprognostic (2.92e-2)" "unprognostic (2.97e-1)" "unprognostic (2.67e-2)" "unprognostic (1.54e-1)" "unprognostic (3.16e-2)" "unprognostic (1.75e-2)" CCDC88B "BRLZ, CCDC88, FLJ00354, FLJ37970, GIPIE, HkRP3" ENSG00000168071 "Coiled-coil domain containing 88B" A6NC98 11 64340204-64357534 "Predicted intracellular proteins" "Stress response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 85.3;lymphoid tissue: 84.4" "Cell type enhanced" "Detected in many" "Foveolar cells: 79.0;Neutrophil progenitors: 172.9;Neutrophils: 177.0;Tuft cells: 103.8" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 54.9;leukocyte: 52.7;upper rhombic lip: 35.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 5 "head and neck cancer: 5.7;Leukemia: 22.5;lymphoma: 20.2;Myeloma: 15.4" "Adipose visceral - T-cells, Colon - T-cells, Prostate - T-cells, Skeletal muscle - Macrophages, Thyroid gland - T-cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA026652 Approved Supported Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 35: RS4;11 - Unknown function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 32 "Centrosome, Cytosol" Nucleoplasm "HPA026652: " "unprognostic (2.06e-2)" "unprognostic (3.71e-2)" "unprognostic (4.15e-3)" "unprognostic (4.56e-3)" "unprognostic (3.06e-1)" "unprognostic (3.18e-1)" "unprognostic (5.47e-2)" "unprognostic (6.24e-2)" "potential prognostic favorable (6.20e-4)" "unprognostic (3.04e-1)" "potential prognostic unfavorable (1.23e-6)" "unprognostic (2.78e-3)" "unprognostic (1.25e-1)" "unprognostic (4.44e-2)" "unprognostic (4.56e-2)" "unprognostic (4.63e-2)" "unprognostic (2.65e-1)" "unprognostic (3.42e-2)" "unprognostic (1.57e-1)" "unprognostic (5.86e-2)" "unprognostic (1.02e-1)" "unprognostic (1.56e-1)" "unprognostic (2.77e-1)" "unprognostic (1.19e-1)" "unprognostic (9.64e-2)" "unprognostic (7.94e-2)" "unprognostic (7.92e-3)" "unprognostic (6.97e-3)" "unprognostic (7.70e-2)" "unprognostic (1.36e-1)" "unprognostic (9.05e-2)" CCDC88C "DAPLE, HkRP2, KIAA1509, SCA40" ENSG00000015133 "Coiled-coil domain containing 88C" Q9P219 14 91271323-91417844 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Wnt signaling pathway" "Guanine-nucleotide releasing factor" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 37.7" "Cell type enhanced" "Detected in many" "B-cells: 176.3;Endometrial ciliated cells: 152.2;NK-cells: 249.0;Pituitary stem cells: 169.2;Plasma cells: 246.1;Respiratory ciliated cells: 246.3;Respiratory deuterosomal cells: 160.7;T-cells: 219.9" "Cell type enhanced" "Detected in many" "ependymal cell: 138.9;leukocyte: 315.7;medium spiny neuron: 222.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "basal ganglia: 47.2" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Myeloma: 50.1" "Colon - T-cells, Spleen - B-cells (Spleen), Testis - Spermatogonia, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "basal ganglia: 42.5" "HPA002726, HPA005832, HPA064745" Approved Enhanced "Cell Junctions" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 33: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 5 "Cell Junctions" "HPA002726: , HPA005832: , HPA064745: " "unprognostic (1.46e-2)" "unprognostic (1.27e-1)" "unprognostic (1.23e-1)" "unprognostic (7.03e-3)" "unprognostic (1.52e-1)" "unprognostic (2.76e-1)" "unprognostic (5.31e-2)" "unprognostic (3.61e-3)" "unprognostic (1.06e-3)" "unprognostic (1.15e-1)" "unprognostic (2.33e-1)" "unprognostic (1.67e-1)" "unprognostic (3.81e-2)" "unprognostic (3.19e-2)" "unprognostic (1.45e-1)" "unprognostic (1.53e-3)" "unprognostic (2.64e-1)" "unprognostic (6.92e-2)" "unprognostic (1.88e-1)" "unprognostic (3.31e-1)" "unprognostic (4.63e-2)" "unprognostic (1.78e-2)" "unprognostic (1.55e-2)" "unprognostic (3.00e-1)" "unprognostic (3.32e-1)" "unprognostic (1.41e-1)" "unprognostic (8.09e-2)" "unprognostic (1.53e-1)" "unprognostic (2.38e-1)" "unprognostic (2.75e-2)" "unprognostic (3.38e-2)" CCDC89 FLJ38159 ENSG00000179071 "Coiled-coil domain containing 89" Q8N998 11 85683848-85686195 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 7.3;testis: 24.3" "Group enriched" "Detected in some" 8 "Early spermatids: 432.6;Late primary spermatocytes: 363.9" "Cell type enriched" "Detected in many" 4 "ependymal cell: 17.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 3.0" "Lung - Respiratory ciliated cells, Spleen - Fibroblasts_1, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA040628 Enhanced Approved Nucleoplasm NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 5: Rhabdoid - Unknown function" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 4 Nucleoplasm "HPA040628: " "unprognostic (1.26e-1)" "unprognostic (1.04e-1)" "potential prognostic unfavorable (5.72e-4)" "potential prognostic favorable (3.35e-8)" "unprognostic (3.30e-3)" "unprognostic (2.31e-1)" "unprognostic (8.07e-2)" "unprognostic (2.76e-1)" "unprognostic (2.14e-3)" CCDC9 DKFZP586M1019 ENSG00000105321 "Coiled-coil domain containing 9" Q9Y3X0 19 47255980-47273701 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Late spermatids: 722.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045624, HPA072007" Enhanced Approved Cytosol NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 23: Choroid plexus - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 19 Cytosol "HPA045624: , HPA072007: " "unprognostic (2.02e-3)" "unprognostic (9.30e-2)" "unprognostic (1.55e-1)" "unprognostic (1.62e-3)" "unprognostic (3.48e-2)" "potential prognostic unfavorable (9.85e-5)" "unprognostic (1.97e-1)" "unprognostic (9.91e-3)" "unprognostic (3.14e-3)" "unprognostic (3.58e-2)" "unprognostic (1.29e-1)" "unprognostic (4.61e-2)" "unprognostic (7.97e-2)" "unprognostic (1.45e-2)" "unprognostic (4.13e-2)" "unprognostic (2.08e-2)" "unprognostic (2.90e-2)" "unprognostic (2.04e-1)" "unprognostic (2.38e-2)" "unprognostic (1.06e-1)" "unprognostic (2.46e-1)" "unprognostic (6.15e-2)" "unprognostic (7.86e-3)" "unprognostic (3.14e-1)" "unprognostic (5.28e-1)" "unprognostic (9.12e-2)" "unprognostic (8.52e-2)" "unprognostic (1.22e-1)" "unprognostic (4.64e-2)" "unprognostic (8.97e-3)" "unprognostic (2.52e-1)" CCDC90B "MDS011, MDS025" ENSG00000137500 "Coiled-coil domain containing 90B" Q9GZT6 11 83259081-83286390 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early primary spermatocytes: 244.7;Early spermatids: 452.8;Esophageal apical cells: 266.2;Late primary spermatocytes: 510.1;Late spermatids: 306.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011130, HPA011931" Supported Enhanced Mitochondria NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 36: Brain & Liver - Signaling" "Cluster 21: Non-specific - Metabolism" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 15 Mitochondria "HPA011130: , HPA011931: " "unprognostic (3.51e-2)" "unprognostic (2.59e-1)" "unprognostic (2.18e-1)" "unprognostic (6.67e-3)" "unprognostic (4.28e-2)" "potential prognostic unfavorable (1.09e-4)" "unprognostic (1.15e-1)" "unprognostic (1.15e-2)" "unprognostic (5.02e-2)" "unprognostic (1.73e-1)" "potential prognostic favorable (1.30e-7)" "unprognostic (1.47e-2)" "unprognostic (2.15e-1)" "unprognostic (5.41e-2)" "unprognostic (1.83e-1)" "potential prognostic unfavorable (6.85e-5)" "unprognostic (3.59e-2)" "unprognostic (2.29e-1)" "unprognostic (3.89e-2)" "unprognostic (3.67e-1)" "unprognostic (9.37e-2)" "unprognostic (3.52e-3)" "unprognostic (1.16e-2)" "unprognostic (2.79e-1)" "unprognostic (1.17e-1)" "unprognostic (2.42e-1)" "unprognostic (3.39e-2)" "unprognostic (1.87e-1)" "unprognostic (1.63e-1)" "unprognostic (3.68e-1)" "unprognostic (2.42e-1)" CCDC91 "DKFZp779L1558, FLJ11088, p56" ENSG00000123106 "Coiled-coil domain containing 91" Q7Z6B0 12 28133249-28581511 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Late spermatids: 14270.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038169 Approved Approved "Nucleoplasm,Golgi apparatus,Acrosome,Equatorial segment,Flagellar centriole" NA NA "Cluster 32: Basophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 1 "Nucleoplasm, Golgi apparatus, Acrosome" "Equatorial segment, Flagellar centriole" "HPA038169: " "unprognostic (2.53e-1)" "unprognostic (4.56e-3)" "unprognostic (1.82e-1)" "potential prognostic unfavorable (1.98e-4)" "unprognostic (1.43e-3)" "unprognostic (6.31e-2)" "unprognostic (4.78e-2)" "unprognostic (1.00e-2)" "unprognostic (1.15e-2)" "potential prognostic unfavorable (4.13e-5)" "unprognostic (1.33e-3)" "unprognostic (2.51e-3)" "unprognostic (1.16e-1)" "potential prognostic unfavorable (3.59e-5)" "unprognostic (5.81e-2)" "unprognostic (1.71e-2)" "unprognostic (1.56e-1)" "unprognostic (1.26e-1)" "unprognostic (3.04e-1)" "unprognostic (1.06e-1)" "unprognostic (1.01e-2)" "unprognostic (1.29e-2)" "potential prognostic unfavorable (4.50e-5)" "unprognostic (2.11e-1)" "unprognostic (6.16e-2)" "potential prognostic favorable (2.55e-4)" "unprognostic (7.74e-3)" "unprognostic (7.36e-2)" "unprognostic (4.91e-2)" "unprognostic (2.46e-1)" "unprognostic (1.87e-1)" CCDC92 FLJ22471 ENSG00000119242 "Coiled-coil domain containing 92" Q53HC0 12 123918660-123972831 "Predicted intracellular proteins" "Host-virus interaction, Immunity, Innate immunity" "Antiviral protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 138.0" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 131.6;Brain inhibitory neurons: 126.0;Other brain neurons: 109.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038560, HPA057580" Approved Approved Nucleoplasm,Vesicles,Centrosome NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 109: Neurons - Neuronal signaling" 12 "Nucleoplasm, Centrosome" Vesicles "HPA038560: , HPA057580: " "unprognostic (1.07e-2)" "unprognostic (1.41e-1)" "unprognostic (2.37e-1)" "unprognostic (6.89e-2)" "unprognostic (9.41e-2)" "unprognostic (7.28e-2)" "unprognostic (1.55e-1)" "unprognostic (2.56e-1)" "unprognostic (1.16e-1)" "unprognostic (1.58e-3)" "potential prognostic favorable (1.84e-4)" "unprognostic (7.58e-2)" "unprognostic (3.81e-2)" "unprognostic (6.32e-2)" "unprognostic (2.51e-2)" "unprognostic (3.86e-2)" "unprognostic (2.81e-1)" "unprognostic (5.44e-3)" "unprognostic (2.61e-1)" "unprognostic (2.63e-1)" "unprognostic (1.47e-1)" "unprognostic (2.03e-3)" "unprognostic (3.87e-2)" "unprognostic (2.41e-1)" "unprognostic (4.27e-1)" "unprognostic (5.54e-3)" "unprognostic (1.64e-1)" "unprognostic (4.58e-2)" "unprognostic (1.32e-1)" "unprognostic (1.07e-1)" "unprognostic (1.12e-1)" CCDC92B ENSG00000277200 "Coiled-coil domain containing 92B" 17 2720801-2749652 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "brain: 4.6;retina: 3.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 12.4;Differentiating spermatogonia: 18.1;Gonadotrophs: 15.5;Lactotrophs: 14.4;Pancreatic islet cells: 14.1;Retinal amacrine cells: 19.6;Retinal bipolar cells: 21.6;Retinal ganglion cells: 15.5;Retinal horizontal cells: 24.0;Rod photoreceptor cells: 22.2;Somatotrophs: 17.1;Thyrotrophs: 13.2;Undifferentiated spermatogonia: 26.4" "Low cell type specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 5.6" "Adrenal gland - Adrenal medulla cells, Pancreas - Alpha cells, Pancreas - Beta cells, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" CCDC93 FLJ10996 ENSG00000125633 "Coiled-coil domain containing 93" Q567U6 2 117915478-118014133 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 217.5;Neutrophils: 258.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Vascular endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054183 Approved Enhanced "Vesicles,Plasma membrane" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 74 Vesicles "Plasma membrane" "HPA054183: " "unprognostic (7.47e-3)" "unprognostic (1.66e-1)" "unprognostic (5.06e-3)" "unprognostic (3.12e-2)" "unprognostic (1.75e-1)" "unprognostic (1.86e-2)" "unprognostic (5.54e-2)" "unprognostic (2.64e-2)" "unprognostic (7.38e-3)" "potential prognostic unfavorable (1.02e-4)" "unprognostic (5.74e-3)" "unprognostic (2.13e-2)" "unprognostic (2.63e-1)" "potential prognostic unfavorable (8.35e-6)" "unprognostic (3.04e-3)" "unprognostic (2.11e-1)" "unprognostic (1.02e-1)" "unprognostic (3.04e-1)" "unprognostic (1.50e-1)" "unprognostic (8.81e-2)" "unprognostic (5.12e-2)" "unprognostic (1.58e-2)" "potential prognostic unfavorable (4.46e-4)" "unprognostic (1.30e-1)" "unprognostic (2.54e-3)" "unprognostic (1.09e-1)" "unprognostic (7.63e-3)" "unprognostic (9.13e-2)" "unprognostic (3.24e-1)" "unprognostic (4.35e-3)" "unprognostic (1.90e-2)" CCDC96 FLJ90575 ENSG00000173013 "Coiled-coil domain containing 96" Q2M329 4 7040849-7043001 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 61.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.2" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 6.4" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" HPA047546 Enhanced NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" 4 "HPA047546: " "unprognostic (1.55e-1)" "unprognostic (2.08e-2)" "unprognostic (1.42e-1)" "unprognostic (6.37e-2)" "unprognostic (1.37e-2)" "unprognostic (1.14e-3)" "unprognostic (4.41e-3)" "unprognostic (1.08e-1)" "unprognostic (4.62e-3)" "unprognostic (4.06e-3)" "unprognostic (2.01e-3)" "unprognostic (1.37e-1)" "unprognostic (2.64e-1)" "unprognostic (2.71e-2)" "unprognostic (9.31e-2)" "unprognostic (2.42e-2)" "potential prognostic favorable (5.80e-4)" "unprognostic (2.84e-1)" "unprognostic (1.58e-1)" "unprognostic (1.83e-2)" "unprognostic (9.09e-2)" "unprognostic (5.15e-2)" CCDC97 "FLJ40267, MGC20255" ENSG00000142039 "Coiled-coil domain containing 97" Q96F63 19 41310172-41324873 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Innate lymphoid cells: 82.2;NK-cells: 78.8;pDCs: 97.4;T-cells: 84.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043320, HPA043572" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 20: Non-specific - Transcription regulation" 43 Nucleoplasm "Plasma membrane, Cytosol" "HPA043320: , HPA043572: " "unprognostic (1.05e-3)" "unprognostic (7.62e-2)" "unprognostic (2.36e-1)" "unprognostic (1.59e-2)" "unprognostic (2.02e-1)" "unprognostic (1.90e-1)" "unprognostic (3.05e-1)" "unprognostic (3.29e-1)" "unprognostic (5.87e-3)" "unprognostic (1.68e-1)" "unprognostic (3.32e-3)" "unprognostic (1.31e-2)" "unprognostic (4.07e-2)" "potential prognostic unfavorable (3.85e-5)" "unprognostic (7.42e-3)" "unprognostic (5.23e-2)" "unprognostic (1.05e-1)" "unprognostic (3.46e-3)" "unprognostic (1.71e-2)" "unprognostic (5.59e-2)" "unprognostic (1.44e-1)" "unprognostic (3.91e-3)" "unprognostic (7.90e-2)" "unprognostic (2.56e-1)" "unprognostic (1.19e-1)" "unprognostic (1.93e-1)" "unprognostic (1.30e-3)" "unprognostic (2.75e-1)" "unprognostic (1.30e-1)" "unprognostic (7.04e-2)" "unprognostic (9.55e-2)" CCDC9B "C15orf52, FLJ43339" ENSG00000188549 "Coiled-coil domain containing 9B" Q6ZUT6 15 40331452-40340939 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 57.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 24.2;Cardiomyocytes: 43.0;Esophageal apical cells: 52.0;Megakaryocytes: 37.1;Myonuclei: 45.3" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 16.4;fibroblast: 19.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Ductal cells, Prostate - Smooth muscle cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040484, HPA041834" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 55: Myocytes - Oxidative muscle function" 1 "Nucleoplasm, Cytosol" "HPA040484: , HPA041834: " "potential prognostic favorable (7.60e-4)" "unprognostic (1.60e-2)" "unprognostic (6.27e-2)" "unprognostic (3.08e-2)" "unprognostic (3.66e-1)" "unprognostic (3.00e-2)" "unprognostic (1.19e-1)" "unprognostic (1.95e-1)" "unprognostic (2.95e-2)" "unprognostic (6.22e-2)" "unprognostic (1.15e-2)" "unprognostic (1.14e-2)" "unprognostic (1.56e-2)" "unprognostic (1.04e-1)" "unprognostic (2.28e-1)" "unprognostic (1.06e-1)" "unprognostic (2.93e-2)" "unprognostic (3.65e-3)" "unprognostic (5.01e-2)" "unprognostic (6.39e-3)" "unprognostic (9.01e-3)" "unprognostic (1.19e-1)" "unprognostic (2.56e-1)" "unprognostic (2.09e-2)" "unprognostic (2.42e-1)" "unprognostic (1.04e-1)" "unprognostic (9.54e-2)" "unprognostic (3.69e-3)" "unprognostic (1.56e-1)" CCER1 "C12orf12, MGC26598" ENSG00000197651 "Coiled-coil glutamate rich protein 1" Q8TC90 12 90905622-90955176 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 363 "testis: 36.2" "Group enriched" "Detected in some" 116 "Early spermatids: 455.3;Late primary spermatocytes: 395.5;Late spermatids: 131.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "amygdala: 1.3;basal ganglia: 1.4;cerebral cortex: 1.4;hippocampal formation: 1.4" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 11 CCER2 ENSG00000262484 "Coiled-coil glutamate rich protein 2" I3L3R5 19 38908980-38912186 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 4.7;testis: 4.7" "Cell type enriched" "Detected in some" 7 "Basal keratinocytes: 38.8" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in some" 5 "Bladder Urothelial Carcinoma (TCGA): 10.1;Glioblastoma Multiforme (TCGA): 4.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 7.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA069716 Uncertain "Secreted - unknown location" "No annotated function" NA NA 9100 "Cluster 68: Non-specific - Basic cellular processes" "Cluster 9: Non-specific - Receptor signaling" "Cluster 11: Neuronal - Sensory perception" "Cluster 26: Keratinocytes - Keratinization" "HPA069716: " "unprognostic (2.59e-2)" "unprognostic (1.07e-1)" "unprognostic (7.76e-2)" "unprognostic (2.30e-1)" "unprognostic (9.45e-2)" "unprognostic (1.71e-2)" CCHCR1 "C6orf18, HCR" ENSG00000204536 "Coiled-coil alpha-helical rod protein 1" Q8TD31 6 31142439-31158238 "Predicted intracellular proteins" Differentiation "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "testis: 129.4" "Cell type enhanced" "Detected in many" "Early spermatids: 56.6;Late primary spermatocytes: 96.4;Late spermatids: 174.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA054167 Supported Cytosol NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 17: Choroid plexus - Cilium" "Cluster 28: Non-specific - Nuclear processes" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 40 Cytosol "HPA054167: " "unprognostic (2.01e-1)" "unprognostic (6.59e-2)" "unprognostic (2.25e-1)" "unprognostic (2.83e-1)" "unprognostic (1.50e-1)" "unprognostic (2.08e-1)" "unprognostic (2.20e-1)" "unprognostic (5.86e-2)" "unprognostic (3.99e-2)" "unprognostic (1.40e-1)" "unprognostic (9.72e-3)" "unprognostic (7.57e-3)" "unprognostic (6.99e-2)" "unprognostic (5.72e-2)" "potential prognostic unfavorable (4.97e-5)" "unprognostic (2.50e-1)" "unprognostic (1.73e-2)" "unprognostic (1.80e-1)" "unprognostic (8.66e-3)" "unprognostic (2.17e-1)" "unprognostic (3.44e-2)" "unprognostic (5.29e-2)" "unprognostic (3.26e-2)" "unprognostic (7.67e-2)" "unprognostic (7.21e-2)" "unprognostic (1.19e-1)" "unprognostic (1.03e-1)" "unprognostic (2.25e-1)" "unprognostic (8.13e-2)" "unprognostic (5.05e-2)" "unprognostic (7.97e-2)" CCIN "BTBD20, KBTBD14" ENSG00000185972 Calicin Q13939 9 36169388-36171334 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 39 "testis: 70.2" "Cell type enhanced" "Detected in some" "Early spermatids: 1121.2;Late primary spermatocytes: 230.1;Late spermatids: 304.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Adipose progenitor cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA019611, HPA058717" Supported "Nucleoplasm,Perinuclear theca,Calyx" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 51: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 4 Calyx "Nucleoplasm, Perinuclear theca" "HPA019611: , HPA058717: " "unprognostic (1.51e-1)" "unprognostic (3.22e-2)" CCK ENSG00000187094 Cholecystokinin P06307 3 42257825-42266185 "Plasma proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "brain: 431.5;intestine: 108.7" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 93.5;Brain inhibitory neurons: 202.4;Conjunctival goblet cells: 27.2;Corticotrophs: 90.0;Gastric progenitor cells: 32.0;Müller glia: 27.3;Neuroendocrine cells: 171.7;Other brain neurons: 42.7" "Cell type enhanced" "Detected in many" "CGE interneuron: 1498.4;LAMP5-LHX6 and Chandelier: 889.3" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 19.0;Prostate Adenocarcinoma (TCGA): 16.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "Bone cancer: 82.2;Gastric cancer: 52.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 107.8" "HPA045039, HPA069515" Enhanced Supported "Secreted to blood" Hormone NA NA 43700000 11000 "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" 33 "HPA045039: , HPA069515: " "unprognostic (1.20e-1)" "unprognostic (2.74e-1)" "unprognostic (1.57e-1)" "unprognostic (9.85e-2)" "unprognostic (1.31e-1)" "unprognostic (2.15e-1)" "unprognostic (3.98e-1)" "unprognostic (3.01e-1)" "unprognostic (1.64e-1)" "unprognostic (2.39e-1)" "unprognostic (2.13e-1)" CCKAR ENSG00000163394 "Cholecystokinin A receptor" P32238 4 26481396-26490484 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "gallbladder: 27.3;stomach 1: 15.6" "Group enriched" "Detected in some" 5 "Gastric chief cells: 31.7;Mucous neck cells: 25.4" "Cell type enhanced" "Detected in some" "hippocampal CA1-3: 2.1;mammillary body: 3.8;oligodendrocyte precursor cell: 2.2" "Cancer enriched" "Detected in single" 5 "Kidney Chromophobe (TCGA): 4.0" "Group enriched" "Detected in many" 5 "hypothalamus: 11.0;midbrain: 14.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Bone cancer: 4.3;liver cancer: 2.0;Neuroblastoma: 7.5" "Stomach - Chief cells, Testis - Late spermatids" "Region enhanced" "Detected in many" "hypothalamus: 7.2" "Region enhanced" "Detected in many" "midbrain: 16.5" HPA073900 Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 60: Stomach - Digestion" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 97: Non-specific - Cellular respiration" "Plasma membrane, Cytosol" Nucleoplasm "HPA073900: " "unprognostic (3.21e-3)" "unprognostic (2.28e-1)" "unprognostic (5.11e-2)" CCKBR ENSG00000110148 "Cholecystokinin B receptor" P32239 11 6259806-6272127 "Cancer-related genes, FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 33 "brain: 21.1;pancreas: 25.5;stomach 1: 41.3" "Group enriched" "Detected in some" 4 "Gastric chief cells: 53.5;Granulosa cells: 72.2;Mucous neck cells: 45.8;Neuroendocrine cells: 32.3;Parietal cells: 83.1" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in some" 9 "Testicular Germ Cell Tumor (TCGA): 26.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Rhabdoid: 2.5;testis cancer: 9.7" "Adipose visceral - Mesothelial cells, Stomach - Parietal cells" "Low region specificity" "Detected in many" HPA079548 Uncertain "Vesicles,Plasma membrane" NA NA "Cluster 70: Non-specific - Protein processing" "Cluster 53: Neurons - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 7 Vesicles "Plasma membrane" "HPA079548: " "unprognostic (2.47e-1)" "unprognostic (3.00e-2)" "unprognostic (1.56e-1)" "unprognostic (2.61e-2)" "unprognostic (5.48e-1)" "unprognostic (3.19e-2)" CCL1 "I-309, P500, SCYA1, SISe, TCA3" ENSG00000108702 "C-C motif chemokine ligand 1" P22362 17 34360328-34363233 "Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 2.1;lymphoid tissue: 1.1" "Group enriched" "Detected in some" 7 "Early spermatids: 3.2;Late spermatids: 2.5;T-cells: 2.6;Thymocytes: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Leukemia: 7.9;lymphoma: 28.6" "Testis - Late spermatids" HPA049861 Uncertain "Secreted to blood" Chemokine NA NA 84400 "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 53: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" 1 "HPA049861: " "unprognostic (2.30e-1)" CCL11 "eotaxin, MGC22554, SCYA11" ENSG00000172156 "C-C motif chemokine ligand 11" P51671 17 34285742-34288334 "Cancer-related genes, Human disease related genes, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 42.9;lymphoid tissue: 29.6;stomach 1: 33.1;urinary bladder: 38.2" "Cell type enriched" "Detected in some" 13 "Fibroblasts: 42.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Stomach Adenocarcinoma (TCGA): 20.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted to blood" Chemokine NA NA 88500 "Cluster 17: Intestine - Digestion" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 4 "unprognostic (3.16e-2)" "unprognostic (1.75e-1)" "unprognostic (7.34e-2)" "unprognostic (3.84e-2)" "unprognostic (1.47e-1)" "unprognostic (4.11e-2)" "potential prognostic favorable (4.29e-4)" "unprognostic (7.90e-2)" "unprognostic (1.34e-1)" "unprognostic (4.28e-2)" "unprognostic (5.85e-2)" "unprognostic (4.84e-2)" "unprognostic (1.56e-2)" "unprognostic (5.17e-2)" "unprognostic (1.04e-2)" "unprognostic (8.82e-2)" "unprognostic (5.83e-2)" "unprognostic (6.32e-2)" "unprognostic (3.09e-2)" "unprognostic (2.53e-1)" "unprognostic (4.18e-2)" "unprognostic (2.30e-3)" CCL13 "CKb10, MCP-4, MGC17134, NCC-1, SCYA13, SCYL1" ENSG00000181374 "C-C motif chemokine ligand 13" Q99616 17 34356480-34358610 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 30.8;urinary bladder: 28.3" "Cell type enhanced" "Detected in some" "cDC: 20.6;Hofbauer cells: 109.2;Macrophages: 40.7;Pericytes: 8.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 28.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Macrophages" "Secreted to blood" Chemokine NA NA 336000 "Cluster 77: Intestine - Digestion" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 82: Dendritic cells - Antigen presentation" 3 "unprognostic (1.05e-1)" "unprognostic (3.69e-2)" "unprognostic (2.65e-2)" "unprognostic (8.08e-2)" "unprognostic (7.35e-2)" "unprognostic (3.82e-1)" "unprognostic (2.28e-3)" "potential prognostic unfavorable (1.09e-4)" "unprognostic (1.72e-1)" "potential prognostic unfavorable (5.04e-4)" "unprognostic (4.82e-1)" "unprognostic (7.93e-2)" "unprognostic (7.44e-3)" "unprognostic (1.67e-1)" "unprognostic (7.50e-2)" "unprognostic (1.13e-1)" "unprognostic (1.24e-1)" "unprognostic (1.41e-2)" "unprognostic (2.68e-2)" "unprognostic (3.65e-3)" "unprognostic (1.06e-2)" "unprognostic (2.87e-2)" "unprognostic (3.28e-1)" "unprognostic (3.25e-1)" "unprognostic (1.97e-1)" "unprognostic (2.03e-1)" "unprognostic (3.51e-1)" CCL14 "CKb1, HCC-1, HCC-3, MCIF, NCC-2, SCYA14, SCYL2" ENSG00000276409 "C-C motif chemokine ligand 14" Q16627 17 35983288-35987004 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 696.1" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 17 "endothelial cell: 11.9" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in single" 6 "choroid plexus: 5.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Endothelial cells, Colon - Endothelial cells, Liver - Sinusoid Endothelial cells, Minor Salivary Gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "CAB004423, HPA030268" Uncertain "Secreted to blood" Chemokine NA NA 5200000 26000000 "Cluster 5: Spleen - Immune response" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "CAB004423: , HPA030268: " "unprognostic (3.45e-1)" "unprognostic (3.44e-2)" "potential prognostic favorable (1.58e-4)" "unprognostic (6.23e-3)" "unprognostic (3.20e-2)" "unprognostic (1.41e-2)" "unprognostic (7.86e-2)" "unprognostic (1.17e-1)" "unprognostic (7.05e-3)" "unprognostic (2.20e-1)" "unprognostic (3.12e-3)" "unprognostic (1.77e-1)" "validated prognostic favorable (1.44e-4)" "validated prognostic favorable (3.06e-5)" "unprognostic (1.33e-3)" "unprognostic (2.00e-1)" "unprognostic (2.13e-2)" "unprognostic (1.42e-1)" "unprognostic (3.75e-2)" "unprognostic (3.26e-2)" "unprognostic (9.15e-3)" "unprognostic (1.47e-2)" "unprognostic (8.16e-2)" "unprognostic (2.83e-1)" "potential prognostic unfavorable (1.26e-4)" "unprognostic (2.23e-1)" "unprognostic (8.64e-2)" "unprognostic (9.52e-3)" CCL15 "HCC-2, HMRP-2B, Lkn-1, MIP-1d, MIP-5, NCC-3, SCYA15, SCYL3" ENSG00000275718 "C-C motif chemokine ligand 15" Q16663 17 35996440-36001553 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Chemotaxis "Cytokine, Heparin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "intestine: 77.7;liver: 40.2" "Cell type enhanced" "Detected in some" "Colonocytes: 7.8;Enteric stem cells: 3.9;Enteric transient amplifying cells: 5.9;Enterocytes: 19.2;Fallopian tube ciliated cells: 1.9;Goblet cells: 7.8;Neuroendocrine cells: 2.6;Paneth cells: 3.9" "Cell type enhanced" "Detected in single" "ependymal cell: 2.4" "Group enriched" "Detected in many" 4 "Colon Adenocarcinoma (TCGA): 45.7;Liver Hepatocellular Carcinoma (TCGA): 63.8;Rectum Adenocarcinoma (TCGA): 44.4;Stomach Adenocarcinoma (TCGA): 21.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "colorectal cancer: 24.6;Gastric cancer: 10.9;liver cancer: 14.1" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Pancreas - Ductal cells" "HPA046429, HPA058608" Approved "Golgi apparatus,Vesicles" "Secreted to blood" Chemokine NA NA 3270000 2700000 "Cluster 77: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 1: Enterocytes - Absorption and Digestion" "Golgi apparatus" Vesicles "HPA046429: , HPA058608: " "unprognostic (4.66e-2)" "potential prognostic favorable (3.43e-4)" "unprognostic (1.80e-2)" "unprognostic (1.89e-1)" "unprognostic (1.55e-1)" "unprognostic (1.40e-1)" "unprognostic (1.97e-1)" "unprognostic (1.76e-2)" "unprognostic (3.64e-2)" "unprognostic (2.77e-1)" "unprognostic (1.80e-1)" "unprognostic (2.27e-1)" "unprognostic (1.06e-1)" "unprognostic (2.77e-2)" "unprognostic (6.08e-2)" "unprognostic (6.21e-2)" "unprognostic (3.14e-1)" CCL16 "CKb12, HCC-4, LCC-1, LEC, LMC, Mtn-1, NCC-4, SCYA16, SCYL4" ENSG00000275152 "C-C motif chemokine ligand 16" O15467 17 35976493-35981497 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 44 "liver: 112.4" "Cell type enriched" "Detected in single" 139 "Hepatocytes: 72.4" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 130 "Liver Hepatocellular Carcinoma (TCGA): 51.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes, Skin - Endothelial cells" "Low region specificity" "Detected in many" "Secreted to blood" Chemokine NA NA 2780000 2000000 "Cluster 53: Liver - Plasma proteins" "Cluster 18: Liver cancer - Metabolism" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 2 "unprognostic (2.31e-2)" "unprognostic (1.08e-2)" CCL17 "ABCD-2, SCYA17, TARC" ENSG00000102970 "C-C motif chemokine ligand 17" Q92583 16 57404767-57416063 "Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 19.6" "Cell type enriched" "Detected in some" 4 "cDC: 124.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 39 "lymphoma: 215.8" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "basal ganglia: 5.7" CAB002583 Uncertain "Secreted to blood" Chemokine NA NA 248000 "Cluster 80: Thymus - Adaptive immune response" "Cluster 53: Neurons - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 82: Dendritic cells - Antigen presentation" 7 "CAB002583: " "unprognostic (2.92e-1)" "unprognostic (1.47e-2)" "unprognostic (1.10e-1)" "unprognostic (5.07e-3)" "unprognostic (1.49e-2)" "unprognostic (1.76e-2)" "unprognostic (1.92e-2)" "unprognostic (2.67e-1)" "unprognostic (3.44e-3)" "unprognostic (3.04e-1)" "unprognostic (9.48e-2)" "unprognostic (1.85e-2)" "unprognostic (1.94e-1)" "unprognostic (1.56e-1)" "unprognostic (2.37e-1)" "unprognostic (4.39e-2)" "unprognostic (3.71e-1)" "unprognostic (1.23e-1)" "unprognostic (3.22e-2)" "unprognostic (1.38e-1)" "unprognostic (1.74e-1)" "unprognostic (8.22e-3)" "unprognostic (2.50e-1)" "unprognostic (9.01e-3)" "unprognostic (3.40e-3)" "unprognostic (1.63e-1)" CCL18 "AMAC-1, CKb7, DC-CK1, DCCK1, MIP-4, PARC, SCYA18" ENSG00000275385 "C-C motif chemokine ligand 18" P55774 17 36064272-36072032 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lung: 46.6" "Group enriched" "Detected in some" 9 "Early spermatids: 9.4;Late spermatids: 4.7;Macrophages: 4.0" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Heart muscle - Macrophages, Lung - Macrophages, Minor Salivary Gland - Macrophages, Spleen - Macrophages, Testis - Early spermatids, Testis - Late spermatids" "Secreted to blood" Chemokine NA NA 55500000 2000000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 1 "unprognostic (1.63e-1)" "unprognostic (3.76e-1)" "unprognostic (2.13e-1)" "unprognostic (5.68e-2)" "unprognostic (1.59e-1)" "unprognostic (7.20e-2)" "unprognostic (2.63e-1)" "unprognostic (5.78e-3)" "unprognostic (2.50e-2)" "unprognostic (1.01e-1)" "unprognostic (1.92e-1)" "unprognostic (6.19e-2)" "unprognostic (2.54e-1)" "unprognostic (1.27e-2)" "unprognostic (2.18e-1)" "unprognostic (1.35e-1)" "unprognostic (3.38e-1)" "unprognostic (3.22e-2)" "unprognostic (5.39e-2)" "unprognostic (8.80e-3)" CCL19 "CKb11, ELC, exodus-3, MIP-3b, SCYA19" ENSG00000172724 "C-C motif chemokine ligand 19" Q99731 9 34689570-34691276 "Cancer-related genes, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 591.4" "Cell type enhanced" "Detected in some" "Fibroblasts: 48.1;Medullary thymic epithelial cells: 79.2;Pericytes: 218.7;Vascular smooth muscle cells: 34.0" "Cell type enriched" "Detected in some" 27 "vascular associated smooth muscle cell: 165.0" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 217.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 25 "breast cancer: 9.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA067758 Enhanced "Secreted to blood" Chemokine NA NA 195000 "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 27: Breast cancer - Unknown function" "Cluster 110: Mural cells - ECM organization" "HPA067758: " "unprognostic (8.71e-2)" "potential prognostic favorable (1.50e-4)" "unprognostic (7.37e-3)" "potential prognostic favorable (1.44e-7)" "unprognostic (3.78e-2)" "unprognostic (3.98e-1)" "unprognostic (3.71e-1)" "unprognostic (3.08e-1)" "unprognostic (9.37e-3)" "unprognostic (3.32e-1)" "unprognostic (5.15e-3)" "unprognostic (9.24e-2)" "potential prognostic unfavorable (5.71e-5)" "unprognostic (8.48e-3)" "unprognostic (5.48e-3)" "unprognostic (3.29e-2)" "unprognostic (2.32e-1)" "unprognostic (1.27e-1)" "unprognostic (4.65e-2)" "unprognostic (3.06e-2)" "unprognostic (1.06e-1)" "unprognostic (8.50e-2)" "unprognostic (8.59e-2)" "unprognostic (1.01e-1)" "unprognostic (9.38e-2)" "unprognostic (1.33e-1)" "unprognostic (3.83e-2)" "unprognostic (4.53e-2)" "unprognostic (2.34e-3)" "unprognostic (1.63e-1)" "unprognostic (2.64e-1)" CCL2 "GDCF-2, HC11, MCAF, MCP-1, MCP1, MGC9434, SCYA2, SMC-CF" ENSG00000108691 "C-C motif chemokine ligand 2" P13500 17 34255274-34257208 "Cancer-related genes, Candidate cardiovascular disease genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "urinary bladder: 701.0" "Cell type enhanced" "Detected in many" "Epididymal basal cells: 1001.1;Epididymal efferent duct absorptive cells: 1702.4;Epididymal efferent duct ciliated cells: 1814.0;Fallopian secretory cells: 1595.7;Hepatic stellate cells: 503.5;Hofbauer cells: 587.4;Pancreatic duct cells: 2177.0;Pericytes: 1395.1;Schwann cells: 722.6;Smooth muscle cells: 926.1;Vascular smooth muscle cells: 1093.5" "Cell type enhanced" "Detected in some" "fibroblast: 54.4;vascular associated smooth muscle cell: 21.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 7.6;eosinophil: 3.1" "Group enriched" "Detected in many" 6 "granulocytes: 3.1;monocytes: 7.6" "Low cancer specificity" "Detected in many" "Pancreas - Ductal cells" "Low region specificity" "Detected in some" "Group enriched" "Detected in all" 4 "midbrain: 13.1;spinal cord: 52.4" "CAB013676, HPA019163" Approved Approved "Golgi apparatus,Vesicles" "Secreted to blood" Chemokine NA NA 323000 46000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 12: Non-specific - Vasculature" "Cluster 49: HMC-1 - Innate immune response" "Cluster 103: Non-specific - Basic cellular processes" 4 "Golgi apparatus" Vesicles "CAB013676: , HPA019163: " "unprognostic (3.16e-1)" "unprognostic (2.08e-1)" "unprognostic (2.74e-2)" "unprognostic (4.05e-2)" "unprognostic (1.30e-1)" "unprognostic (3.15e-1)" "potential prognostic unfavorable (5.74e-5)" "unprognostic (1.33e-3)" "unprognostic (3.92e-2)" "unprognostic (1.49e-1)" "unprognostic (1.94e-1)" "unprognostic (1.41e-1)" "unprognostic (2.71e-2)" "unprognostic (1.13e-1)" "unprognostic (6.68e-2)" "unprognostic (1.01e-1)" "unprognostic (1.72e-2)" "unprognostic (3.04e-3)" "unprognostic (3.80e-2)" "unprognostic (3.41e-1)" "unprognostic (1.67e-2)" "unprognostic (7.09e-2)" "unprognostic (8.04e-2)" "unprognostic (1.38e-1)" "unprognostic (9.59e-2)" "unprognostic (3.58e-2)" "unprognostic (1.37e-1)" "unprognostic (4.77e-2)" "unprognostic (1.22e-2)" "unprognostic (1.01e-1)" "unprognostic (1.69e-1)" CCL20 "CKb4, exodus-1, LARC, MIP-3a, SCYA20, ST38" ENSG00000115009 "C-C motif chemokine ligand 20" P78556 2 227805739-227817564 "Predicted secreted proteins" "Chemotaxis, Inflammatory response" "Antibiotic, Antimicrobial, Cytokine" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "gallbladder: 153.1;lymphoid tissue: 155.0;urinary bladder: 179.3" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 784.1;Enterocytes: 349.9;Esophageal apical cells: 721.8;Esophageal basal cells: 329.4;Esophageal suprabasal cells: 647.9;Fallopian secretory cells: 263.2;Gastric progenitor cells: 472.9;monocytes: 883.6;Neutrophils: 593.0;Pancreatic duct cells: 227.0" "Group enriched" "Detected in some" 34 "central nervous system macrophage: 4.8;leukocyte: 3.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 2.7" "Lineage enriched" "Detected in single" 9 "T-cells: 2.7" "Low cancer specificity" "Detected in many" "Pancreas - Ductal cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" Chemokine NA NA 28000 "Cluster 1: T-cells - Unknown function" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 34: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 4 "unprognostic (3.07e-2)" "unprognostic (8.84e-2)" "unprognostic (4.38e-1)" "unprognostic (1.01e-1)" "unprognostic (9.53e-2)" "potential prognostic favorable (1.46e-4)" "unprognostic (5.79e-2)" "potential prognostic unfavorable (7.78e-4)" "unprognostic (3.39e-3)" "unprognostic (4.57e-2)" "unprognostic (2.59e-1)" "unprognostic (4.29e-3)" "potential prognostic unfavorable (8.25e-5)" "potential prognostic unfavorable (5.48e-4)" "unprognostic (1.23e-3)" "unprognostic (1.32e-3)" "unprognostic (4.52e-2)" "unprognostic (1.98e-1)" "unprognostic (1.01e-2)" "unprognostic (3.29e-2)" "unprognostic (1.86e-1)" "unprognostic (1.02e-3)" "unprognostic (6.41e-3)" "unprognostic (1.38e-1)" "unprognostic (7.30e-2)" "unprognostic (1.26e-1)" "unprognostic (2.92e-1)" "unprognostic (8.29e-2)" "unprognostic (1.41e-1)" "unprognostic (8.12e-2)" "unprognostic (3.67e-2)" CCL21 "6Ckine, CKb9, ECL, exodus-2, SCYA21, SLC, TCA4" ENSG00000137077 "C-C motif chemokine ligand 21" O00585 9 34709005-34710136 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 2551.0" "Cell type enriched" "Detected in some" 43 "Lymphatic endothelial cells: 6468.6" "Cell type enriched" "Detected in single" 10 "vascular associated smooth muscle cell: 1.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skeletal muscle - Smooth muscle cells, Stomach - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA051210 Enhanced "Secreted to blood" Chemokine NA NA 198000 8500000 "Cluster 18: Lymphoid tissue - Immune response" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 8 "HPA051210: " "unprognostic (1.78e-3)" "unprognostic (3.14e-3)" "unprognostic (1.66e-2)" "unprognostic (7.19e-3)" "unprognostic (1.16e-1)" "unprognostic (7.73e-2)" "unprognostic (1.09e-2)" "unprognostic (2.67e-1)" "unprognostic (5.83e-2)" "unprognostic (1.55e-1)" "potential prognostic unfavorable (7.27e-4)" "unprognostic (1.65e-2)" "unprognostic (1.66e-3)" "unprognostic (7.06e-2)" "unprognostic (5.58e-2)" "unprognostic (1.84e-2)" "unprognostic (1.59e-1)" "unprognostic (4.37e-2)" "unprognostic (4.45e-2)" "unprognostic (5.16e-2)" "unprognostic (2.16e-1)" "unprognostic (3.61e-1)" "unprognostic (8.72e-2)" "unprognostic (1.45e-3)" "unprognostic (9.69e-3)" "unprognostic (8.44e-3)" "unprognostic (2.02e-1)" "unprognostic (2.03e-2)" "unprognostic (1.51e-2)" CCL22 "A-152E5.1, ABCD-1, DC/B-CK, MDC, MGC34554, SCYA22, STCP-1" ENSG00000102962 "C-C motif chemokine ligand 22" O00626 16 57358783-57366189 "Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 13.8;skin 1: 6.2" "Cell type enriched" "Detected in some" 10 "cDC: 159.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in some" 4 "lymphoma: 51.4" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" Chemokine NA NA 617000 "Cluster 20: Non-specific - DNA binding" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 6: Non-specific - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 82: Dendritic cells - Antigen presentation" 1 "unprognostic (2.60e-2)" "unprognostic (5.19e-2)" "unprognostic (2.81e-2)" "unprognostic (2.01e-1)" "unprognostic (1.20e-2)" "unprognostic (1.10e-2)" "potential prognostic favorable (2.41e-4)" "unprognostic (5.79e-3)" "unprognostic (1.84e-1)" "unprognostic (7.00e-2)" "unprognostic (2.12e-1)" "unprognostic (4.74e-1)" "unprognostic (3.14e-2)" "unprognostic (5.54e-3)" "unprognostic (1.23e-2)" "unprognostic (1.34e-1)" "unprognostic (9.31e-2)" "unprognostic (1.11e-2)" "unprognostic (2.12e-2)" "unprognostic (7.23e-2)" "unprognostic (1.09e-2)" "unprognostic (4.60e-2)" "unprognostic (2.57e-2)" CCL23 "Ckb-8, CKb8, MIP-3, MPIF-1, SCYA23" ENSG00000274736 "C-C motif chemokine ligand 23" P55773 17 36013056-36017972 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" "Cytokine, Heparin-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 4 "Vascular endothelial cells: 68.7" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 163 "eosinophil: 184.4" "Lineage enriched" "Detected in many" 163 "granulocytes: 184.4" "Cancer enriched" "Detected in single" 50 "Leukemia: 4.9" "Heart muscle - Macrophages" HPA042015 Uncertain "Secreted to blood" Chemokine NA NA 937000 "Cluster 19: Eosinophils - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 1 "HPA042015: " "unprognostic (1.52e-1)" "unprognostic (1.52e-1)" "unprognostic (2.07e-1)" "unprognostic (4.04e-2)" "unprognostic (1.87e-1)" "unprognostic (1.04e-1)" "unprognostic (2.73e-2)" "unprognostic (9.14e-2)" "unprognostic (7.25e-2)" "unprognostic (2.56e-1)" CCL24 "Ckb-6, eotaxin-2, MPIF-2, MPIF2, SCYA24" ENSG00000106178 "C-C motif chemokine ligand 24" O00175 7 75810825-75823356 "Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 66.6;lymphoid tissue: 76.9" "Cell type enhanced" "Detected in some" "cDC: 28.5;Early spermatids: 18.2;Goblet cells: 47.7;Kupffer cells: 109.7;Macrophages: 70.9;Paneth cells: 154.7" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Colon Adenocarcinoma (TCGA): 106.4;Pancreatic Adenocarcinoma (TCGA): 28.8;Rectum Adenocarcinoma (TCGA): 110.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 9 "colorectal cancer: 26.1" "Spleen - Macrophages, Testis - Late spermatids" "Low region specificity" "Detected in single" "Region enriched" "Detected in many" 4 "spinal cord: 13.6" "Secreted to blood" Chemokine NA NA 276000 "Cluster 5: Spleen - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 1 "unprognostic (9.81e-2)" "unprognostic (7.80e-2)" "unprognostic (1.31e-1)" "unprognostic (1.67e-1)" "unprognostic (9.16e-2)" "unprognostic (1.50e-2)" "unprognostic (4.53e-2)" "unprognostic (3.80e-1)" "unprognostic (1.31e-2)" "unprognostic (1.08e-1)" "unprognostic (9.84e-2)" "unprognostic (1.18e-1)" "unprognostic (2.75e-1)" "unprognostic (1.45e-1)" "unprognostic (2.49e-3)" "unprognostic (1.75e-1)" "unprognostic (2.62e-2)" "unprognostic (1.52e-2)" "unprognostic (1.45e-2)" "unprognostic (5.04e-2)" "unprognostic (6.85e-2)" "unprognostic (3.62e-3)" CCL25 "Ckb15, SCYA25, TECK" ENSG00000131142 "C-C motif chemokine ligand 25" O15444 19 8052318-8062660 "Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 997 "intestine: 547.3;lymphoid tissue: 718.3" "Group enriched" "Detected in some" 11 "Enteric stem cells: 329.0;Enteric transient amplifying cells: 387.9;Enterocytes: 660.7;Paneth cells: 874.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 32.6;Stomach Adenocarcinoma (TCGA): 50.8" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 5 "NK-cell: 3.5" "Lineage enriched" "Detected in single" 5 "NK-cells: 3.5" "Cancer enhanced" "Detected in single" "breast cancer: 2.7" "Low region specificity" "Detected in all" HPA055883 Approved "Secreted to blood" Chemokine NA NA 183000000 "Cluster 24: Non-specific - Transcription" "Cluster 80: Thymus - Adaptive immune response" "Cluster 70: DU4475 - Unknown function" "Cluster 1: Enterocytes - Absorption and Digestion" 4 "HPA055883: " "unprognostic (2.38e-1)" "unprognostic (3.21e-1)" "unprognostic (1.25e-2)" "unprognostic (3.67e-2)" "unprognostic (2.19e-2)" "potential prognostic favorable (8.27e-4)" "unprognostic (3.58e-1)" "unprognostic (2.48e-1)" "unprognostic (7.97e-2)" "unprognostic (2.98e-2)" "unprognostic (1.06e-1)" CCL26 "eotaxin-3, IMAC, MIP-4a, MIP-4alpha, SCYA26, TSC-1" ENSG00000006606 "C-C motif chemokine ligand 26" Q9Y258 7 75769533-75789896 "Human disease related genes, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "choroid plexus: 45.8;ovary: 22.0;pituitary gland: 18.2" "Cell type enhanced" "Detected in some" "Esophageal suprabasal cells: 7.4;Fibroblasts: 11.7;Gastric progenitor cells: 15.4;Goblet cells: 6.4;Hepatic stellate cells: 12.9;Kupffer cells: 9.2;Leydig cells: 10.8;Ovarian stromal cells: 25.9;Pericytes: 37.6;Peritubular myoid cells: 6.5;Rod photoreceptor cells: 7.0" "Group enriched" "Detected in some" 16 "fibroblast: 6.7;pericyte: 4.0;vascular associated smooth muscle cell: 5.2" "Group enriched" "Detected in many" 4 "Head and Neck Squamous Cell Carcinoma (TCGA): 13.4;Lung Squamous Cell Carcinoma (TCGA): 11.2;Pancreatic Adenocarcinoma (TCGA): 9.8;Stomach Adenocarcinoma (TCGA): 9.8;Testicular Germ Cell Tumor (TCGA): 30.5" "Region enriched" "Detected in some" 18 "choroid plexus: 18.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "ovarian cancer: 77.0" "Kidney - Fibroblasts" "Region enriched" "Detected in single" 16 "spinal cord: 3.1" "Secreted to blood" Chemokine NA NA 117000 "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 110: Mural cells - ECM organization" 6 "unprognostic (3.63e-3)" "unprognostic (1.34e-1)" "unprognostic (8.81e-2)" "unprognostic (9.04e-2)" "unprognostic (7.64e-2)" "unprognostic (2.12e-1)" "unprognostic (9.20e-2)" "unprognostic (2.84e-2)" "unprognostic (1.86e-3)" "potential prognostic unfavorable (5.34e-4)" "unprognostic (5.91e-3)" "unprognostic (1.36e-1)" "unprognostic (3.32e-2)" "unprognostic (5.11e-2)" "unprognostic (1.84e-1)" "unprognostic (1.33e-1)" "unprognostic (2.71e-1)" "unprognostic (1.49e-1)" "unprognostic (1.71e-1)" "unprognostic (2.34e-1)" "unprognostic (1.45e-1)" "unprognostic (6.17e-2)" "unprognostic (9.21e-2)" "unprognostic (2.44e-1)" "unprognostic (3.52e-1)" CCL27 "ALP, CTACK, CTAK, ESkine, ILC, PESKY, SCYA27, skinkine" ENSG00000213927 "C-C motif chemokine ligand 27" Q9Y4X3 9 34661880-34664048 "Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "skin 1: 456.6" "Group enriched" "Detected in some" 4 "Basal keratinocytes: 4.8;Suprabasal keratinocytes: 2.9" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in some" "Skin Cutaneous Melanoma (TCGA): 3.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" HPA073848 Enhanced "Secreted to blood" Chemokine NA NA 436000 "Cluster 37: Skin - Keratinization" "Cluster 15: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 26: Keratinocytes - Keratinization" "HPA073848: " "unprognostic (6.23e-3)" "unprognostic (7.90e-3)" "unprognostic (1.51e-2)" "unprognostic (2.60e-2)" "unprognostic (6.28e-2)" CCL28 "CCK1, MEC, SCYA28" ENSG00000151882 "C-C motif chemokine ligand 28" Q9NRJ3 5 43376645-43412391 "Predicted intracellular proteins, Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "salivary gland: 283.0" "Cell type enhanced" "Detected in many" "Breast lactating cells: 566.7;Breast secretory cells: 533.6;Colonocytes: 205.3;Lacrimal acinar cells: 1366.0;Salivary acinar cells: 1223.3;Salivary basal cells: 235.8;Salivary duct cells: 319.8;Salivary ionocytes: 266.0;Salivary myoepithelial cells: 323.7;Submucosal glandular cells: 307.3" "Cell type enhanced" "Detected in many" "endothelial cell: 19.1;leukocyte: 13.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Minor salivary glandular cells, Spleen - Endothelial cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA077434 Supported "Secreted to blood" Chemokine NA NA 700000000 10000000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 82: Salivary gland - Secretion" "Cluster 30: White matter - Myelination" "Cluster 15: Kidney cancer - Membrane components" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 8 "HPA077434: " "unprognostic (4.62e-2)" "unprognostic (4.55e-2)" "unprognostic (2.00e-1)" "unprognostic (6.62e-2)" "potential prognostic favorable (9.38e-4)" "unprognostic (5.42e-2)" "unprognostic (2.28e-2)" "unprognostic (3.42e-1)" "potential prognostic favorable (7.15e-5)" "unprognostic (3.34e-2)" "unprognostic (2.87e-3)" "unprognostic (2.79e-3)" "unprognostic (4.05e-1)" "unprognostic (8.74e-2)" "unprognostic (1.14e-1)" "unprognostic (4.11e-2)" "unprognostic (8.84e-2)" "unprognostic (1.80e-2)" "unprognostic (2.26e-2)" "potential prognostic unfavorable (2.28e-4)" "unprognostic (2.62e-2)" "unprognostic (1.90e-1)" "unprognostic (2.91e-2)" "unprognostic (8.69e-3)" "unprognostic (1.42e-3)" "unprognostic (1.80e-1)" "unprognostic (7.66e-2)" "unprognostic (8.20e-2)" "unprognostic (2.14e-2)" CCL3 "G0S19-1, LD78ALPHA, MIP-1-alpha, SCYA3" ENSG00000277632 "C-C motif chemokine ligand 3" P10147 17 36088256-36090169 "Cancer-related genes, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 72.7;lung: 35.3;lymphoid tissue: 48.7" "Cell type enhanced" "Detected in some" "cDC: 17.2;Hofbauer cells: 94.3;Kupffer cells: 45.1;Macrophages: 48.4;Microglia: 35.0;monocytes: 30.9;NK-cells: 62.7" "Group enriched" "Detected in some" 82 "central nervous system macrophage: 29.7;leukocyte: 43.7" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 19 "basal ganglia: 1.5;cerebral cortex: 2.7;medulla oblongata: 1.4;thalamus: 1.0;white matter: 2.7" "Immune cell enhanced" "Detected in many" "gdT-cell: 23.7" "Group enriched" "Detected in many" 4 "B-cells: 10.4;granulocytes: 10.8;T-cells: 23.7" "Cancer enriched" "Detected in some" 5 "Myeloma: 218.9" "Thyroid gland - T-cells" "Secreted to blood" Chemokine NA NA 138000 "Cluster 14: Non-specific - Unknown function" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 34: Non-specific - Mixed function" "Cluster 20: Myeloma - Immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 3 "unprognostic (2.25e-1)" "unprognostic (1.31e-1)" "unprognostic (1.98e-1)" "unprognostic (1.86e-1)" "unprognostic (6.44e-2)" "unprognostic (2.38e-1)" "unprognostic (2.29e-1)" "unprognostic (3.56e-2)" "unprognostic (5.43e-3)" "unprognostic (1.79e-1)" "unprognostic (2.20e-2)" "unprognostic (7.25e-2)" "unprognostic (6.98e-2)" "unprognostic (4.66e-2)" "unprognostic (6.84e-2)" "potential prognostic favorable (4.21e-4)" "unprognostic (1.98e-1)" CCL3L1 "CCL3L3, D17S1718, G0S19-2, LD78BETA, MGC12815, SCYA3L, SCYA3L1" ENSG00000276085 "C-C motif chemokine ligand 3 like 1" P16619 17 36194869-36196758 "Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 10.5;lung: 5.1" "Group enriched" "Detected in some" 5 "cDC: 3.8;Hofbauer cells: 2.5;Macrophages: 8.8;Microglia: 10.0;monocytes: 6.7;Neutrophils: 5.3;NK-cells: 3.9;pDCs: 2.6" "Cell type enriched" "Detected in some" 4 "central nervous system macrophage: 8.1" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "eosinophil: 4.2;neutrophil: 1.2" "Lineage enriched" "Detected in single" 9 "granulocytes: 4.2" "Group enriched" "Detected in some" 11 "lymphoma: 2.3;Myeloma: 9.1" "Secreted to blood" Chemokine NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 20: Myeloma - Immune response" "Cluster 82: Dendritic cells - Antigen presentation" 5 "unprognostic (7.63e-3)" "unprognostic (4.70e-2)" "unprognostic (1.02e-1)" "unprognostic (4.51e-2)" CCL4 "Act-2, AT744.1, LAG1, MIP-1-beta, SCYA4" ENSG00000275302 "C-C motif chemokine ligand 4" P13236 17 36103827-36105621 "Cancer-related genes, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 181.9" "Cell type enhanced" "Detected in some" "cDC: 59.5;Hofbauer cells: 85.3;Kupffer cells: 45.1;Late spermatids: 47.3;Macrophages: 100.9;Mast cells: 39.2;monocytes: 87.3;Neutrophils: 62.0;NK-cells: 414.0;T-cells: 186.1" "Cell type enriched" "Detected in some" 14 "leukocyte: 286.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "gdT-cell: 416.0" "Group enriched" "Detected in all" 6 "granulocytes: 135.5;T-cells: 416.0" "Cancer enriched" "Detected in some" 4 "lymphoma: 51.1" "Adipose subcutaneous - T-cells, Breast - T-cells, Heart muscle - T-cells, Kidney - T-cells, Prostate - T-cells, Testis - Late spermatids, Thyroid gland - T-cells" "Low region specificity" "Detected in single" CAB007805 Approved "Secreted to blood" Chemokine NA NA 144000 "Cluster 24: Non-specific - Transcription" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 8: Immune cells - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 16 "CAB007805: " "unprognostic (1.41e-2)" "unprognostic (1.57e-1)" "potential prognostic favorable (5.29e-4)" "unprognostic (1.76e-2)" "unprognostic (7.68e-3)" "unprognostic (1.27e-1)" "unprognostic (1.40e-1)" "unprognostic (1.62e-1)" "unprognostic (1.08e-1)" "unprognostic (2.85e-2)" "unprognostic (8.96e-2)" "unprognostic (1.56e-1)" "unprognostic (3.05e-1)" "unprognostic (1.82e-2)" "unprognostic (2.94e-1)" "unprognostic (2.64e-2)" "unprognostic (2.69e-1)" "unprognostic (1.22e-1)" "unprognostic (3.77e-2)" "unprognostic (1.75e-1)" "unprognostic (2.34e-1)" "unprognostic (1.06e-1)" "unprognostic (4.10e-2)" "potential prognostic favorable (1.19e-5)" "unprognostic (6.96e-2)" "unprognostic (2.90e-2)" "unprognostic (3.54e-1)" "unprognostic (1.68e-1)" CCL4L2 ENSG00000276070 "C-C motif chemokine ligand 4 like 2" Q8NHW4 17 36210924-36212878 "Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 30.3;lymphoid tissue: 19.3" "Cell type enhanced" "Detected in some" "cDC: 13.2;Hofbauer cells: 22.2;Kupffer cells: 8.2;Macrophages: 30.9;Mast cells: 9.7;Microglia: 12.3;monocytes: 16.0;Neutrophils: 23.0;NK-cells: 38.8;T-cells: 25.4" "Group enriched" "Detected in some" 6 "central nervous system macrophage: 11.5;leukocyte: 28.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 7 "eosinophil: 122.3" "Lineage enriched" "Detected in many" 8 "granulocytes: 122.3" "Cancer enriched" "Detected in some" 8 "lymphoma: 13.4" "Breast - T-cells, Thyroid gland - T-cells" "Secreted to blood" Chemokine NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 31 "unprognostic (3.29e-2)" "unprognostic (4.14e-1)" "unprognostic (8.37e-2)" "potential prognostic favorable (6.45e-4)" "unprognostic (1.25e-1)" "unprognostic (1.21e-1)" "unprognostic (2.86e-2)" "unprognostic (2.04e-2)" "unprognostic (9.86e-2)" "unprognostic (3.46e-2)" "unprognostic (1.84e-1)" "unprognostic (5.52e-2)" "unprognostic (2.00e-1)" "unprognostic (2.71e-2)" "unprognostic (5.42e-2)" "unprognostic (2.28e-1)" "unprognostic (1.02e-1)" "unprognostic (6.14e-2)" "unprognostic (3.61e-1)" "unprognostic (2.42e-1)" "unprognostic (6.94e-2)" "unprognostic (1.25e-1)" "unprognostic (2.07e-1)" "unprognostic (7.20e-2)" "unprognostic (7.83e-2)" "unprognostic (1.26e-1)" CCL5 "D17S136E, MGC17164, RANTES, SCYA5, SISd, TCP228" ENSG00000271503 "C-C motif chemokine ligand 5" P13501 17 35871491-35880793 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 114.7;lymphoid tissue: 126.6" "Group enriched" "Detected in some" 14 "NK-cells: 175.0;Platelets: 118.1;T-cells: 127.1" "Cell type enriched" "Detected in many" 182 "leukocyte: 573.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "gdT-cell: 6781.0;memory CD8 T-cell: 7136.0" "Group enriched" "Detected in all" 7 "NK-cells: 2043.0;T-cells: 7136.0" "Cancer enhanced" "Detected in many" "Leukemia: 57.4" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Minor Salivary Gland - T-cells, Pancreas - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Skeletal muscle - Fibroblasts, Skin - T-cells, Spleen - T-cells, Stomach - T-cells, Thyroid gland - T-cells" CAB078447 Enhanced "Secreted to blood" Chemokine NA NA 20100000 12000000 "Cluster 1: T-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 30 "CAB078447: " "unprognostic (6.82e-2)" "unprognostic (4.22e-3)" "unprognostic (6.61e-2)" "unprognostic (6.76e-3)" "unprognostic (7.39e-2)" "unprognostic (1.98e-1)" "unprognostic (1.07e-3)" "unprognostic (8.71e-3)" "unprognostic (5.26e-1)" "unprognostic (7.33e-3)" "unprognostic (1.13e-1)" "potential prognostic unfavorable (5.88e-4)" "unprognostic (1.31e-1)" "unprognostic (8.21e-3)" "unprognostic (6.52e-2)" "unprognostic (1.35e-1)" "unprognostic (1.46e-1)" "unprognostic (7.24e-2)" "unprognostic (2.52e-2)" "unprognostic (1.51e-2)" "unprognostic (7.46e-2)" "unprognostic (1.24e-1)" "unprognostic (3.22e-1)" "potential prognostic favorable (3.10e-4)" "unprognostic (4.71e-2)" "unprognostic (5.67e-2)" "unprognostic (3.02e-3)" "unprognostic (1.51e-1)" CCL7 "FIC, MARC, MCP-3, MCP3, NC28, SCYA6, SCYA7" ENSG00000108688 "C-C motif chemokine ligand 7" P80098 17 34270221-34272242 "Cancer-related genes, Predicted membrane proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" "Cytokine, Heparin-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "bone marrow: 24.4" "Group enriched" "Detected in some" 4 "Epididymal basal cells: 6.3;Epididymal efferent duct ciliated cells: 8.8;Fallopian secretory cells: 16.7;Mesothelial cells: 8.2;monocytes: 7.1;Pancreatic duct cells: 15.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 6 "thalamus: 5.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" Chemokine NA NA 29700 "Cluster 15: Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 3 "unprognostic (3.25e-2)" "unprognostic (9.93e-2)" "unprognostic (2.74e-1)" "unprognostic (5.93e-2)" "unprognostic (2.64e-3)" "unprognostic (4.00e-2)" "unprognostic (1.35e-1)" "unprognostic (2.27e-2)" "potential prognostic unfavorable (4.86e-4)" "unprognostic (1.14e-1)" "unprognostic (9.94e-2)" "unprognostic (3.24e-2)" "unprognostic (1.79e-2)" "unprognostic (8.89e-2)" "unprognostic (2.80e-1)" "unprognostic (1.01e-1)" CCL8 "HC14, MCP-2, SCYA8" ENSG00000108700 "C-C motif chemokine ligand 8" P80075 17 34319435-34321402 "Cancer-related genes, Predicted secreted proteins" "Chemotaxis, Inflammatory response" "Cytokine, Heparin-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 5 "Macrophages: 48.7;Pericytes: 112.6;Vascular smooth muscle cells: 105.9" "Cell type enriched" "Detected in single" 9 "central nervous system macrophage: 2.8" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 4 "spinal cord: 2.9;thalamus: 1.6" "Immune cell enriched" "Detected in single" 6 "classical monocyte: 3.4" "Lineage enriched" "Detected in single" 6 "monocytes: 3.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to blood" Chemokine NA NA 32000 "Cluster 77: Intestine - Digestion" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 103: Non-specific - Basic cellular processes" "unprognostic (1.73e-2)" "unprognostic (5.30e-2)" "unprognostic (1.19e-1)" "unprognostic (2.62e-2)" "unprognostic (1.32e-1)" "unprognostic (4.59e-2)" "unprognostic (2.71e-3)" "unprognostic (1.28e-1)" "unprognostic (2.01e-2)" "unprognostic (2.40e-1)" "unprognostic (1.66e-3)" "unprognostic (1.24e-1)" "unprognostic (1.38e-1)" "unprognostic (1.93e-1)" "unprognostic (2.56e-1)" "unprognostic (3.71e-2)" "unprognostic (2.44e-2)" "unprognostic (2.72e-1)" "unprognostic (1.38e-1)" "unprognostic (9.87e-3)" "unprognostic (4.94e-2)" "unprognostic (1.04e-1)" "unprognostic (1.61e-2)" "unprognostic (6.74e-2)" "unprognostic (3.77e-2)" "unprognostic (4.10e-1)" "unprognostic (1.32e-1)" "unprognostic (5.91e-3)" "unprognostic (8.96e-2)" "unprognostic (1.83e-1)" CCM2 "C7orf22, MGC4607, OSM" ENSG00000136280 "CCM2 scaffold protein" Q9BSQ5 7 44999475-45076469 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 135.4" "Cell type enhanced" "Detected in all" "Neutrophils: 277.7" "Cell type enhanced" "Detected in all" "leukocyte: 303.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020273, HPA021669, HPA065815" Supported Enhanced Mitochondria NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 78: Brain - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 21 Mitochondria "HPA020273: , HPA021669: , HPA065815: " "unprognostic (1.47e-1)" "unprognostic (5.82e-2)" "unprognostic (3.11e-2)" "unprognostic (4.88e-2)" "unprognostic (1.01e-1)" "unprognostic (1.01e-2)" "potential prognostic unfavorable (5.00e-5)" "unprognostic (2.65e-2)" "unprognostic (1.12e-1)" "unprognostic (5.89e-2)" "unprognostic (5.62e-3)" "unprognostic (2.19e-2)" "unprognostic (5.97e-2)" "unprognostic (5.58e-2)" "unprognostic (4.25e-1)" "validated prognostic unfavorable (4.63e-4)" "validated prognostic unfavorable (8.37e-4)" "unprognostic (2.68e-2)" "unprognostic (1.51e-1)" "unprognostic (9.83e-2)" "unprognostic (7.17e-2)" "unprognostic (4.29e-3)" "unprognostic (1.37e-2)" "unprognostic (3.59e-2)" "unprognostic (1.72e-1)" "unprognostic (1.92e-1)" "unprognostic (2.39e-1)" "unprognostic (1.04e-1)" "unprognostic (1.47e-1)" "unprognostic (3.64e-2)" "unprognostic (1.99e-1)" CCM2L "C20orf160, dJ310O13.5" ENSG00000101331 "CCM2 like scaffold protein" Q9NUG4 20 32010438-32032180 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "lymphoid tissue: 98.9" "Group enriched" "Detected in some" 5 "Lymphatic endothelial cells: 56.4;Tuft cells: 34.6;Vascular endothelial cells: 56.0" "Group enriched" "Detected in many" 5 "endothelial cell: 102.2;pericyte: 81.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Prostate - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008434, HPA071063" Uncertain Approved Nucleoplasm NA NA "Cluster 5: Spleen - Immune response" "Cluster 37: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 3 Nucleoplasm "HPA008434: , HPA071063: " "unprognostic (1.41e-1)" "unprognostic (2.26e-1)" "unprognostic (1.93e-2)" "unprognostic (5.31e-2)" "unprognostic (4.34e-2)" "unprognostic (1.30e-1)" "unprognostic (1.73e-1)" "unprognostic (4.22e-1)" "potential prognostic favorable (2.13e-7)" "unprognostic (9.29e-3)" "potential prognostic unfavorable (3.72e-4)" "unprognostic (1.56e-3)" "unprognostic (1.53e-1)" "unprognostic (1.85e-1)" "unprognostic (5.79e-3)" "unprognostic (3.02e-1)" "unprognostic (8.79e-2)" "unprognostic (2.89e-1)" "potential prognostic favorable (5.63e-4)" "unprognostic (3.82e-2)" "unprognostic (1.47e-2)" "unprognostic (9.12e-2)" "unprognostic (1.61e-1)" "unprognostic (1.73e-1)" "unprognostic (2.70e-2)" "unprognostic (1.91e-1)" "unprognostic (2.00e-1)" "unprognostic (5.90e-3)" CCN1 "CYR61, GIG1, IGFBP10" ENSG00000142871 "Cellular communication network factor 1" O00622 1 85580761-85584589 "Predicted secreted proteins" "Cell adhesion, Chemotaxis" "Growth factor binding, Heparin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 471.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 614.0;Basal keratinocytes: 603.1;Breast secretory cells: 713.4;Decidual stromal cells: 1900.1;Endometrial glandular cells: 639.9;Endometrial luminal cells: 715.2;Endometrial secretory cells: 762.0;Epididymal basal cells: 1411.8;Epididymal efferent duct absorptive cells: 882.6;Extravillous trophoblasts: 747.1;Fibroblasts: 577.9;Hepatic stellate cells: 1362.0;Migrating cytotrophoblasts: 878.5;Pancreatic duct cells: 773.5;Smooth muscle cells: 678.9" "Cell type enhanced" "Detected in many" "endothelial cell: 104.7;ependymal cell: 265.2;vascular associated smooth muscle cell: 190.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Minor Salivary Gland - Minor salivary glandular cells, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029853 Uncertain "Secreted to extracellular matrix" "Cell adhesion" NA NA 500000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 108: Fibroblasts - ECM organization" 6 "HPA029853: " "unprognostic (4.03e-2)" "unprognostic (2.77e-2)" "potential prognostic unfavorable (1.14e-4)" "unprognostic (4.11e-1)" "unprognostic (7.58e-2)" "unprognostic (1.60e-1)" "unprognostic (2.74e-2)" "unprognostic (1.82e-1)" "unprognostic (1.41e-1)" "potential prognostic favorable (5.59e-5)" "unprognostic (1.00e-1)" "unprognostic (5.63e-2)" "unprognostic (9.34e-2)" "unprognostic (5.76e-3)" "unprognostic (1.44e-1)" "unprognostic (2.06e-3)" "unprognostic (1.27e-1)" "unprognostic (1.14e-2)" "unprognostic (3.61e-1)" "unprognostic (6.16e-2)" "unprognostic (1.63e-2)" "unprognostic (1.97e-1)" "unprognostic (1.32e-1)" "potential prognostic favorable (7.90e-5)" "unprognostic (1.68e-1)" "unprognostic (6.39e-3)" "unprognostic (7.59e-2)" "unprognostic (1.33e-2)" "unprognostic (1.25e-1)" CCN2 "CTGF, IGFBP8" ENSG00000118523 "Cellular communication network factor 2" P29279 6 131948176-131951372 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion, DNA synthesis" Heparin-binding "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 1230.3" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 522.7;Endometrial glandular cells: 311.1;Endometrial luminal cells: 368.6;Epididymal efferent duct ciliated cells: 383.6;Fallopian tube ciliated cells: 322.5;Fibroblasts: 340.1;Hepatic stellate cells: 2033.3;Pancreatic duct cells: 628.1;Peritubular myoid cells: 439.4;Podocytes: 979.7;Respiratory ciliated cells: 317.4;Salivary myoepithelial cells: 361.8;Smooth muscle cells: 350.2;Vascular endothelial cells: 413.1" "Cell type enhanced" "Detected in many" "deep-layer corticothalamic and 6b: 109.0;endothelial cell: 185.1;vascular associated smooth muscle cell: 99.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "naive B-cell: 8.1" "Lineage enriched" "Detected in single" 81 "B-cells: 8.1" "Low cancer specificity" "Detected in all" "Liver - Hepatic stellate cells, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002976, CAB005123, HPA031074, HPA031075" Approved Approved "Golgi apparatus,Vesicles" "Secreted in other tissues" "Cell adhesion" No No 8300000 "Cluster 34: B-cells - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 6 "Golgi apparatus" Vesicles "CAB005123: , HPA002976: , HPA031074: , HPA031075: " "unprognostic (5.29e-2)" "unprognostic (1.96e-1)" "unprognostic (1.28e-1)" "unprognostic (9.13e-2)" "unprognostic (4.17e-2)" "unprognostic (9.66e-2)" "potential prognostic unfavorable (4.21e-4)" "unprognostic (3.32e-2)" "unprognostic (9.15e-2)" "unprognostic (1.18e-1)" "unprognostic (3.41e-2)" "unprognostic (3.04e-2)" "unprognostic (2.96e-1)" "unprognostic (1.45e-1)" "unprognostic (2.01e-1)" "unprognostic (1.24e-2)" "unprognostic (2.18e-1)" "unprognostic (1.13e-2)" "unprognostic (8.41e-2)" "unprognostic (2.64e-1)" "unprognostic (1.16e-1)" "unprognostic (2.55e-1)" "unprognostic (1.42e-1)" "potential prognostic favorable (2.99e-5)" "unprognostic (6.45e-2)" "potential prognostic unfavorable (4.39e-4)" "unprognostic (1.70e-1)" "unprognostic (1.40e-2)" "unprognostic (5.95e-2)" CCN3 "IGFBP9, NOV" ENSG00000136999 "Cellular communication network factor 3" P48745 8 119416446-119424434 "Plasma proteins, Predicted secreted proteins, Transporters" "Growth factor, Hormone" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 33 "adrenal gland: 1044.7;blood vessel: 548.1" "Cell type enriched" "Detected in many" 4 "Adrenal cortex cells: 556.8" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in all" 4 "Skin Cutaneous Melanoma (TCGA): 111.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 116 "eosinophil: 64.9;neutrophil: 30.9" "Lineage enriched" "Detected in single" 157 "granulocytes: 64.9" "Cancer enhanced" "Detected in many" "lung cancer: 42.6;skin cancer: 67.9" "Adipose visceral - Smooth muscle cells, Adrenal gland - Adrenal cortex cells, Kidney - Fibroblasts, Lung - Smooth muscle cells, Skeletal muscle - Fibroblasts, Thyroid gland - Fibroblasts" "Group enriched" "Detected in all" 6 "amygdala: 129.2;basal ganglia: 51.5;cerebral cortex: 99.5;hippocampal formation: 152.5;white matter: 85.1" "Region enriched" "Detected in all" 6 "spinal cord: 161.3" "HPA019684, CAB034423, HPA072879" Enhanced Enhanced Vesicles,Cytosol "Secreted to blood" Hormone NA NA 269000000 1700000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 51: Neurons - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 62: Smooth muscle cells - Muscle contraction" 16 Vesicles Cytosol "CAB034423: , HPA019684: , HPA072879: " "unprognostic (5.82e-2)" "unprognostic (8.71e-3)" "unprognostic (9.19e-2)" "unprognostic (3.81e-2)" "unprognostic (1.63e-2)" "potential prognostic unfavorable (5.59e-4)" "unprognostic (3.05e-1)" "unprognostic (3.96e-1)" "unprognostic (6.21e-3)" "unprognostic (1.70e-3)" "unprognostic (2.06e-2)" "unprognostic (2.76e-2)" "unprognostic (9.26e-2)" "unprognostic (4.00e-3)" "unprognostic (4.71e-3)" "unprognostic (8.05e-2)" "unprognostic (2.10e-1)" "unprognostic (2.00e-1)" "unprognostic (5.79e-2)" "unprognostic (1.36e-1)" "unprognostic (4.10e-2)" "unprognostic (1.02e-1)" "unprognostic (3.31e-2)" "unprognostic (3.66e-1)" "unprognostic (5.78e-2)" "unprognostic (2.57e-3)" "unprognostic (2.27e-1)" "unprognostic (3.83e-2)" "unprognostic (1.85e-1)" CCN4 "WISP-1, WISP1, WISP1-OT1, WISP1-UT1" ENSG00000104415 "Cellular communication network factor 4" O95388 8 133191039-133231690 "Cancer-related genes, Predicted secreted proteins" "Cell adhesion, Wnt signaling pathway" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 18.8" "Cell type enhanced" "Detected in many" "Endometrial luminal cells: 10.1;Epicardial cells: 18.2;Fibroblasts: 36.0;Gonadotrophs: 10.5;Hepatic stellate cells: 38.7;Mesothelial cells: 14.7;Ovarian stromal cells: 11.3;Pericytes: 23.1;Vascular smooth muscle cells: 12.9" "Cell type enhanced" "Detected in some" "deep-layer intratelencephalic: 40.7;fibroblast: 65.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Brain cancer: 22.9;thyroid cancer: 12.5" "Testis - Peritubular cells" "Region enriched" "Detected in some" 6 "olfactory bulb: 9.8" "Region enhanced" "Detected in some" "spinal cord: 6.2" "HPA007121, CAB012205" Uncertain Approved Cytosol "Secreted to extracellular matrix" "Cell adhesion" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 105: Non-specific - Mixed function" 1 Cytosol "CAB012205: , HPA007121: " "unprognostic (1.45e-2)" "unprognostic (3.91e-1)" "unprognostic (1.14e-1)" "unprognostic (1.38e-1)" "unprognostic (2.77e-1)" "unprognostic (3.35e-2)" "potential prognostic unfavorable (6.35e-4)" "unprognostic (8.21e-2)" "potential prognostic unfavorable (1.23e-4)" "unprognostic (1.82e-1)" "unprognostic (1.16e-1)" "potential prognostic unfavorable (6.06e-5)" "unprognostic (3.67e-2)" "unprognostic (3.74e-3)" "unprognostic (4.15e-3)" "unprognostic (2.48e-1)" "unprognostic (1.37e-3)" "potential prognostic unfavorable (5.32e-5)" "unprognostic (1.05e-2)" "unprognostic (2.19e-1)" "unprognostic (1.83e-2)" "unprognostic (9.92e-2)" "unprognostic (1.55e-2)" "unprognostic (1.39e-2)" "unprognostic (1.62e-3)" "unprognostic (4.35e-3)" "unprognostic (7.54e-2)" "unprognostic (2.19e-2)" CCN5 "CT58, CTGF-L, WISP-2, WISP2" ENSG00000064205 "Cellular communication network factor 5" O76076 20 44714844-44728509 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 422.9;blood vessel: 904.2;cervix: 365.6" "Cell type enhanced" "Detected in many" "Fibro-adipogenic progenitors: 158.8;Fibroblasts: 291.8;Hepatic stellate cells: 187.2;Leydig cells: 312.9;Myosatellite cells: 58.4;Ovarian stromal cells: 169.2;Schwann cells: 202.0;Thymic myoid cells: 58.5;Vascular smooth muscle cells: 188.0" "Cell type enhanced" "Detected in many" "vascular associated smooth muscle cell: 11.4" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 50.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Adrenocortical cancer: 64.4;cervical cancer: 37.8;Kidney cancer: 22.6;liver cancer: 46.7;Sarcoma: 34.3" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells, Pancreas - Fibroblasts, Prostate - Smooth muscle cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in single" "Not detected" "Not detected" "CAB019273, HPA072121" Approved Approved "Plasma membrane" "Secreted to extracellular matrix" "Cell adhesion" NA NA 630000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 51: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 108: Fibroblasts - ECM organization" 1 "Plasma membrane" "CAB019273: , HPA072121: " "unprognostic (2.63e-2)" "unprognostic (3.35e-1)" "unprognostic (1.36e-1)" "unprognostic (7.99e-2)" "unprognostic (1.07e-1)" "unprognostic (2.24e-1)" "unprognostic (4.24e-1)" "unprognostic (2.53e-3)" "unprognostic (4.33e-2)" "potential prognostic unfavorable (9.56e-5)" "unprognostic (1.11e-1)" "unprognostic (9.30e-2)" "unprognostic (7.95e-2)" "unprognostic (6.26e-2)" "unprognostic (2.90e-2)" "unprognostic (9.19e-2)" "unprognostic (2.61e-2)" "unprognostic (2.21e-1)" "unprognostic (2.43e-1)" "unprognostic (4.41e-3)" "unprognostic (1.46e-1)" "unprognostic (2.06e-1)" "unprognostic (1.51e-1)" "unprognostic (1.16e-3)" "unprognostic (1.27e-1)" "unprognostic (4.64e-2)" "unprognostic (7.68e-2)" CCN6 "WISP-3, WISP3" ENSG00000112761 "Cellular communication network factor 6" O95389 6 112054075-112069686 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Growth factor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 9.6;skin 1: 2.8" "Group enriched" "Detected in some" 5 "Early spermatids: 119.7;Epididymal principal cells: 46.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 4.9" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA064196 Supported Mitochondria "Secreted to extracellular matrix" "Growth factor" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 3 Mitochondria "HPA064196: " "unprognostic (3.61e-1)" "unprognostic (4.68e-1)" "unprognostic (4.29e-2)" "unprognostic (1.16e-1)" "unprognostic (3.26e-3)" "unprognostic (9.65e-2)" "unprognostic (3.27e-3)" "unprognostic (1.60e-1)" "unprognostic (4.82e-1)" "unprognostic (1.91e-1)" "unprognostic (4.26e-1)" "unprognostic (1.12e-2)" "unprognostic (3.14e-1)" "unprognostic (3.54e-1)" "unprognostic (4.77e-1)" "unprognostic (2.40e-2)" "unprognostic (4.82e-1)" "unprognostic (1.14e-2)" "unprognostic (4.49e-1)" CCNA1 CT146 ENSG00000133101 "Cyclin A1" P78396 13 36431520-36442870 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 20.9;testis: 76.0" "Cell type enriched" "Detected in some" 4 "Late primary spermatocytes: 554.8" "Cell type enhanced" "Detected in many" "ependymal cell: 25.9" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 32.4;Uterine Corpus Endometrial Carcinoma (TCGA): 31.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 104 "basophil: 49.6" "Lineage enriched" "Detected in single" 301 "granulocytes: 49.6" "Cancer enhanced" "Detected in many" "Rhabdoid: 66.7" "Colon - Colon enteroendocrine cells, Lung - Respiratory ciliated cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Spleen - Neutrophils_2, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA060646, HPA077614" Enhanced Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 49: HMC-1 - Innate immune response" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 29 "Nucleoplasm, Nuclear bodies" "HPA060646: , HPA077614: " "potential prognostic unfavorable (8.90e-4)" "unprognostic (1.37e-2)" "unprognostic (3.10e-1)" "unprognostic (3.20e-1)" "unprognostic (3.65e-2)" "unprognostic (1.69e-1)" "potential prognostic unfavorable (2.07e-4)" "unprognostic (3.23e-1)" "unprognostic (3.71e-2)" "unprognostic (4.30e-2)" "unprognostic (4.53e-1)" "unprognostic (1.60e-3)" "unprognostic (2.31e-1)" "unprognostic (2.44e-1)" "unprognostic (9.52e-2)" "unprognostic (1.00e-1)" CCNA2 "CCN1, CCNA" ENSG00000145386 "Cyclin A2" P20248 4 121816444-121823883 "Cancer-related genes, Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Host-virus interaction, Mitosis" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 36.4;lymphoid tissue: 43.6;retina: 29.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 53.1;Differentiating spermatogonia: 37.5;Enteric transient amplifying cells: 60.2;Erythrocyte progenitors: 122.6;Esophageal basal cells: 51.3;Extravillous trophoblasts: 96.8;Hofbauer cells: 35.8;Megakaryocyte progenitors: 65.0;Megakaryocytes: 37.1;Migrating cytotrophoblasts: 91.5;Monocyte progenitors: 143.7;Neutrophil progenitors: 52.6;Oocytes: 46.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 3.2" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Group enriched" "Detected in many" 4 "basal ganglia: 3.4;white matter: 7.6" "Low region specificity" "Detected in all" "CAB000114, HPA020626" Enhanced Enhanced Nucleoplasm,Cytosol Yes Yes "Cluster 9: T-regs - Cell cycle regulation" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Non-specific - Cell proliferation" 98 "Nucleoplasm, Cytosol" "CAB000114: , HPA020626: " "unprognostic (2.72e-2)" "unprognostic (9.35e-2)" "unprognostic (1.35e-1)" "unprognostic (1.04e-2)" "unprognostic (9.85e-3)" "unprognostic (1.94e-1)" "unprognostic (1.33e-1)" "unprognostic (5.83e-3)" "unprognostic (6.38e-2)" "potential prognostic unfavorable (3.24e-4)" "validated prognostic unfavorable (6.09e-7)" "validated prognostic unfavorable (4.21e-4)" "potential prognostic unfavorable (1.51e-5)" "validated prognostic unfavorable (1.55e-5)" "validated prognostic unfavorable (1.34e-6)" "validated prognostic unfavorable (5.17e-6)" "validated prognostic unfavorable (4.74e-4)" "unprognostic (2.62e-2)" "unprognostic (1.25e-1)" "unprognostic (1.05e-1)" "unprognostic (2.83e-2)" "potential prognostic unfavorable (3.55e-5)" "unprognostic (2.65e-3)" "unprognostic (1.70e-3)" "unprognostic (3.15e-2)" "unprognostic (7.15e-2)" "unprognostic (2.34e-2)" "unprognostic (1.39e-1)" "unprognostic (2.11e-1)" "unprognostic (1.14e-2)" "unprognostic (1.18e-1)" CCNB1 CCNB ENSG00000134057 "Cyclin B1" P14635 5 69167135-69178245 "Cancer-related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 49.9;lymphoid tissue: 70.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 117.2;Enteric transient amplifying cells: 101.6;Erythrocyte progenitors: 121.3;Esophageal basal cells: 151.1;Extravillous trophoblasts: 893.1;Gastric progenitor cells: 108.9;Late primary spermatocytes: 147.9;Migrating cytotrophoblasts: 300.4;Monocyte progenitors: 105.5;Oocytes: 294.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Group enriched" "Detected in many" 5 "basal ganglia: 3.0;white matter: 8.3" "Not detected" "Not detected" "CAB000115, CAB003804, HPA030741, HPA061448" Enhanced Enhanced Cytosol Yes Yes "Cluster 14: Non-specific - Unknown function" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 100 Cytosol "CAB000115: , CAB003804: , HPA030741: , HPA061448: " "unprognostic (7.73e-3)" "unprognostic (1.97e-2)" "unprognostic (2.55e-2)" "unprognostic (2.62e-1)" "unprognostic (1.24e-2)" "unprognostic (9.57e-2)" "unprognostic (2.52e-1)" "unprognostic (1.64e-1)" "unprognostic (8.55e-2)" "potential prognostic unfavorable (5.21e-4)" "validated prognostic unfavorable (6.02e-4)" "validated prognostic unfavorable (2.79e-5)" "potential prognostic unfavorable (8.00e-10)" "validated prognostic unfavorable (1.01e-8)" "validated prognostic unfavorable (9.80e-9)" "validated prognostic unfavorable (4.62e-7)" "validated prognostic unfavorable (4.74e-4)" "unprognostic (2.29e-2)" "unprognostic (2.11e-1)" "unprognostic (1.89e-1)" "unprognostic (1.06e-1)" "unprognostic (1.85e-3)" "unprognostic (5.56e-3)" "unprognostic (1.42e-1)" "unprognostic (8.98e-2)" "unprognostic (5.97e-2)" "unprognostic (4.61e-3)" "unprognostic (1.73e-1)" "unprognostic (1.59e-1)" "unprognostic (2.28e-1)" "unprognostic (3.89e-1)" CCNB1IP1 "C14orf18, HEI10" ENSG00000100814 "Cyclin B1 interacting protein 1" Q9NPC3 14 20311368-20333312 "Cancer-related genes, Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" "Meiosis, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 453.3;Late spermatids: 169.1;Oocytes: 262.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 18: Non-specific - Translation" "Cluster 75: Ovary - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 25: Non-specific - Ribosome" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 16 "unprognostic (2.60e-1)" "unprognostic (1.75e-2)" "unprognostic (2.84e-1)" "unprognostic (1.69e-1)" "unprognostic (8.35e-2)" "unprognostic (2.74e-1)" "unprognostic (7.98e-3)" "unprognostic (3.20e-2)" "unprognostic (1.44e-2)" "unprognostic (1.46e-1)" "potential prognostic favorable (2.75e-4)" "unprognostic (4.09e-3)" "unprognostic (9.41e-3)" "unprognostic (9.20e-2)" "unprognostic (1.96e-2)" "unprognostic (3.35e-1)" "unprognostic (4.38e-3)" "unprognostic (4.69e-2)" "unprognostic (6.80e-2)" "unprognostic (1.17e-1)" "unprognostic (4.03e-1)" "unprognostic (2.56e-1)" "unprognostic (1.29e-2)" "unprognostic (1.20e-1)" "unprognostic (4.18e-2)" "unprognostic (9.73e-2)" "unprognostic (1.24e-1)" "unprognostic (4.55e-1)" "unprognostic (4.52e-2)" "unprognostic (2.12e-1)" "unprognostic (5.14e-2)" CCNB2 HsT17299 ENSG00000157456 "Cyclin B2" O95067 15 59105126-59125045 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 70.4;lymphoid tissue: 68.1;testis: 64.9" "Group enriched" "Detected in many" 4 "Late primary spermatocytes: 552.5;Oocytes: 336.2" "Cell type enhanced" "Detected in some" "vascular associated smooth muscle cell: 3.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "T-reg: 22.7" "Lineage enriched" "Detected in many" 6 "T-cells: 22.7" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA008873, CAB009575" Enhanced Enhanced "Golgi apparatus,Cytosol" Yes Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 11: White matter - Signal transduction" "Cluster 58: Non-specific - Nuclear processes" "Cluster 27: Non-specific - Cell proliferation" 27 Cytosol "Golgi apparatus" "CAB009575: , HPA008873: " "unprognostic (1.35e-2)" "unprognostic (1.98e-2)" "unprognostic (5.48e-2)" "unprognostic (1.84e-1)" "unprognostic (1.77e-1)" "unprognostic (3.14e-1)" "unprognostic (6.72e-2)" "unprognostic (3.96e-2)" "unprognostic (5.58e-2)" "potential prognostic unfavorable (1.33e-5)" "validated prognostic unfavorable (2.37e-9)" "validated prognostic unfavorable (4.98e-5)" "potential prognostic unfavorable (4.74e-13)" "validated prognostic unfavorable (7.26e-5)" "validated prognostic unfavorable (1.08e-7)" "validated prognostic unfavorable (4.65e-6)" "validated prognostic unfavorable (1.99e-4)" "unprognostic (2.66e-2)" "unprognostic (2.08e-1)" "unprognostic (1.85e-1)" "unprognostic (1.03e-1)" "potential prognostic unfavorable (3.54e-5)" "unprognostic (2.97e-3)" "unprognostic (9.01e-2)" "unprognostic (6.29e-3)" "unprognostic (9.09e-2)" "unprognostic (1.29e-3)" "unprognostic (2.90e-1)" "unprognostic (3.78e-1)" "unprognostic (1.77e-1)" "unprognostic (2.53e-1)" CCNB3 CYCB3 ENSG00000147082 "Cyclin B3" Q8WWL7 X 50202713-50351914 "Predicted intracellular proteins" "Cell cycle, Cell division, Meiosis" Cyclin "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 2.6;epididymis: 4.5;testis: 5.8" "Cell type enriched" "Detected in many" 7 "Early primary spermatocytes: 89.4" "Cell type enhanced" "Detected in many" "oligodendrocyte: 17.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Pituitary gland - Somatotropes, Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA000496, HPA001507" Enhanced Supported Nucleoplasm NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 30: White matter - Myelination" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 3: Early primary spermatocytes - Early meiosis" 2 Nucleoplasm "HPA000496: , HPA001507: " "unprognostic (9.12e-2)" "unprognostic (7.35e-3)" CCNC CycC ENSG00000112237 "Cyclin C" P24863 6 99542387-99568825 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Cyclin, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 361.1;Esophageal apical cells: 410.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010499 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 28: Non-specific - Nuclear processes" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 152 Nucleoplasm Cytosol "CAB010499: " "unprognostic (2.12e-1)" "unprognostic (7.82e-3)" "unprognostic (5.10e-2)" "unprognostic (1.05e-2)" "unprognostic (2.17e-2)" "unprognostic (4.42e-3)" "unprognostic (9.48e-2)" "unprognostic (4.66e-3)" "unprognostic (1.79e-3)" "unprognostic (1.13e-2)" "potential prognostic favorable (1.12e-5)" "unprognostic (1.61e-2)" "unprognostic (1.93e-1)" "unprognostic (2.67e-1)" "unprognostic (6.09e-2)" "unprognostic (2.50e-1)" "unprognostic (2.34e-1)" "unprognostic (1.15e-1)" "unprognostic (1.02e-1)" "unprognostic (6.97e-2)" "unprognostic (1.10e-2)" "unprognostic (1.80e-1)" "unprognostic (1.33e-3)" "unprognostic (1.28e-1)" "potential prognostic favorable (8.68e-4)" "unprognostic (5.88e-2)" "unprognostic (5.91e-2)" "unprognostic (3.43e-1)" "unprognostic (2.63e-1)" "unprognostic (7.61e-2)" "unprognostic (9.90e-2)" CCND1 "BCL1, D11S287E, PRAD1, U21B31" ENSG00000110092 "Cyclin D1" P24385 11 69641156-69654474 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, DNA damage, Transcription, Transcription regulation" "Cyclin, Repressor" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 611.9;Epididymal efferent duct absorptive cells: 585.6;Esophageal suprabasal cells: 337.2;Fallopian secretory cells: 396.1;Ocular epithelial cells: 336.9;Pancreatic duct cells: 537.7;Respiratory secretory cells: 328.7;Suprabasal keratinocytes: 314.7" "Group enriched" "Detected in many" 4 "central nervous system macrophage: 60.4;choroid plexus epithelial cell: 24.6;endothelial cell: 33.0;fibroblast: 34.7;oligodendrocyte precursor cell: 91.2;pericyte: 40.5;vascular associated smooth muscle cell: 58.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary gland basal cells, Skeletal muscle - Fibroblasts, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027802, CAB080462" Supported Supported Nucleoplasm Yes No "Cluster 32: Basophils - Transcription" "Cluster 58: Skin - Keratinization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 100: Stratified epithelial cells - Barrier functions" 98 Nucleoplasm "CAB080462: , HPA027802: " "unprognostic (1.44e-1)" "unprognostic (1.60e-1)" "unprognostic (8.16e-3)" "unprognostic (5.12e-2)" "unprognostic (2.39e-1)" "unprognostic (3.44e-2)" "unprognostic (3.66e-1)" "unprognostic (1.85e-2)" "potential prognostic unfavorable (5.23e-4)" "unprognostic (2.57e-2)" "validated prognostic favorable (3.18e-6)" "validated prognostic favorable (5.97e-4)" "unprognostic (2.46e-1)" "unprognostic (5.48e-2)" "unprognostic (4.00e-2)" "unprognostic (9.58e-3)" "unprognostic (2.02e-1)" "unprognostic (2.46e-2)" "unprognostic (4.68e-2)" "unprognostic (1.90e-2)" "unprognostic (6.38e-2)" "potential prognostic unfavorable (2.24e-4)" "unprognostic (1.60e-2)" "unprognostic (4.06e-2)" "unprognostic (3.82e-2)" "unprognostic (9.59e-2)" "unprognostic (2.35e-1)" "unprognostic (8.60e-2)" "unprognostic (7.20e-2)" "unprognostic (7.88e-3)" "unprognostic (2.16e-2)" CCND2 ENSG00000118971 "Cyclin D2" P30279 12 4269771-4305353 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" Cyclin "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 27.8" "Cell type enhanced" "Detected in many" "Epididymal basal cells: 39.6;Megakaryocyte progenitors: 31.1;Megakaryocyte-Erythroid progenitors: 41.9;Müller glia: 47.7;Plasma cells: 53.2;Smooth muscle cells: 40.1" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 76.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Myeloma: 91.6;testis cancer: 82.4" "Heart muscle - Cardiomyocytes, Spleen - Mitotic cells (Spleen), Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049138, HPA054196" Approved Enhanced Nucleoplasm Yes Yes "Cluster 3: Non-specific - Nuclear processes" "Cluster 35: Non-specific - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 44: Plasma cells - Antibody production & secretion" 36 Nucleoplasm "HPA049138: , HPA054196: " "unprognostic (3.15e-1)" "unprognostic (2.77e-2)" "potential prognostic favorable (7.56e-4)" "unprognostic (4.55e-2)" "unprognostic (4.39e-2)" "unprognostic (1.20e-1)" "unprognostic (8.68e-2)" "unprognostic (6.00e-2)" "unprognostic (1.01e-2)" "unprognostic (2.03e-2)" "unprognostic (8.88e-3)" "unprognostic (4.42e-2)" "unprognostic (1.21e-2)" "unprognostic (1.42e-2)" "unprognostic (1.12e-2)" "unprognostic (3.29e-1)" "unprognostic (3.15e-3)" "unprognostic (2.48e-2)" "unprognostic (2.33e-1)" "unprognostic (3.27e-1)" "potential prognostic favorable (9.80e-4)" "unprognostic (2.10e-1)" "unprognostic (1.15e-1)" "unprognostic (9.57e-3)" "unprognostic (1.88e-2)" "unprognostic (3.18e-1)" "unprognostic (1.29e-1)" "unprognostic (2.85e-1)" "unprognostic (6.51e-2)" "unprognostic (2.44e-1)" CCND3 ENSG00000112576 "Cyclin D3" P30281 6 41934934-42050357 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Transcription, Transcription regulation" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 239.0" "Cell type enhanced" "Detected in all" "B-cells: 851.5;Hematopoietic stem cells: 628.8;Innate lymphoid cells: 723.2;Megakaryocytes: 1038.5;Neutrophils: 1913.2;NK-cells: 865.4;Platelets: 1550.3;T-cells: 774.2;Thymocytes: 790.2" "Cell type enhanced" "Detected in all" "endothelial cell: 332.2;leukocyte: 757.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Leukemia: 398.7" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000116, HPA042871" Approved Supported Nucleoplasm,Cytosol NA Yes "Cluster 41: Basophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 6: Leukemia - Signal transduction" "Cluster 9: T-cells - Adaptive immunity: Regulation" 55 Nucleoplasm Cytosol "CAB000116: , HPA042871: " "unprognostic (1.55e-1)" "unprognostic (1.77e-1)" "unprognostic (1.61e-1)" "unprognostic (1.55e-1)" "unprognostic (2.12e-1)" "unprognostic (1.01e-2)" "unprognostic (2.04e-1)" "unprognostic (1.52e-1)" "unprognostic (2.70e-1)" "unprognostic (4.95e-3)" "unprognostic (3.61e-2)" "unprognostic (6.89e-2)" "unprognostic (3.43e-1)" "unprognostic (1.70e-2)" "unprognostic (1.68e-1)" "unprognostic (7.32e-2)" "unprognostic (1.58e-1)" "unprognostic (4.92e-2)" "unprognostic (4.03e-3)" "unprognostic (1.15e-1)" "unprognostic (1.84e-2)" "unprognostic (3.02e-1)" "unprognostic (8.72e-2)" "unprognostic (1.64e-1)" "unprognostic (2.31e-1)" "unprognostic (1.57e-1)" "unprognostic (3.43e-1)" "unprognostic (1.42e-1)" "unprognostic (1.93e-1)" "potential prognostic favorable (2.95e-4)" "unprognostic (1.66e-1)" CCNDBP1 "DIP1, GCIP, HHM" ENSG00000166946 "Cyclin D1 binding protein 1" O95273 15 43185118-43197177 "Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 18.9" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 414.8;Esophageal apical cells: 535.5;Migrating cytotrophoblasts: 304.9;Neutrophils: 269.8;Syncytiotrophoblasts: 1449.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020664, HPA041065" Supported Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 15: Bone marrow - Innate immune response" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 47: Leukemia - Hemostasis" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 104 Nucleoplasm "Nuclear bodies" "CAB020664: , HPA041065: " "unprognostic (9.03e-3)" "unprognostic (3.06e-1)" "unprognostic (9.80e-2)" "unprognostic (8.64e-3)" "unprognostic (1.91e-2)" "unprognostic (3.87e-1)" "unprognostic (5.75e-2)" "unprognostic (4.16e-2)" "unprognostic (8.58e-3)" "potential prognostic favorable (7.95e-4)" "unprognostic (3.08e-3)" "unprognostic (6.46e-3)" "unprognostic (1.63e-2)" "unprognostic (5.73e-2)" "unprognostic (5.40e-2)" "unprognostic (6.90e-2)" "unprognostic (2.22e-3)" "unprognostic (2.54e-1)" "unprognostic (4.05e-1)" "unprognostic (4.27e-2)" "unprognostic (1.19e-1)" "unprognostic (1.23e-1)" "unprognostic (2.40e-1)" "unprognostic (2.25e-1)" "unprognostic (2.13e-1)" CCNE1 CCNE ENSG00000105173 "Cyclin E1" P24864 19 29811991-29824312 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 33.7;placenta: 29.0" "Cell type enriched" "Detected in many" 6 "Extravillous trophoblasts: 2489.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Lung - Mitotic cells (Lung), Prostate - Smooth muscle cells, Spleen - Mitotic cells (Spleen), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000308, CAB016682, HPA018169" Approved Enhanced Nucleoplasm,Cytosol Yes Yes "Cluster 40: Monocytes - Innate immune response" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 1: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 54 Nucleoplasm Cytosol "CAB000308: , CAB016682: , HPA018169: " "unprognostic (7.01e-2)" "unprognostic (6.39e-3)" "unprognostic (1.88e-1)" "unprognostic (4.93e-2)" "unprognostic (1.35e-2)" "unprognostic (1.55e-2)" "unprognostic (8.46e-2)" "unprognostic (1.34e-1)" "unprognostic (8.82e-2)" "potential prognostic unfavorable (2.39e-4)" "validated prognostic unfavorable (4.68e-5)" "validated prognostic unfavorable (1.84e-6)" "potential prognostic unfavorable (4.27e-4)" "validated prognostic unfavorable (1.34e-4)" "validated prognostic unfavorable (2.76e-4)" "potential prognostic unfavorable (8.63e-5)" "unprognostic (7.06e-3)" "unprognostic (2.16e-1)" "unprognostic (1.09e-1)" "unprognostic (2.13e-3)" "unprognostic (2.13e-1)" "potential prognostic unfavorable (2.08e-4)" "unprognostic (4.51e-2)" "unprognostic (1.76e-1)" "unprognostic (6.87e-3)" "unprognostic (3.15e-1)" "unprognostic (8.56e-3)" "unprognostic (1.21e-1)" "unprognostic (2.77e-1)" "unprognostic (8.54e-2)" "unprognostic (2.36e-2)" CCNE2 CYCE2 ENSG00000175305 "Cyclin E2" O96020 8 94879770-94896678 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 34.9;brain: 17.4" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 37.0;Colonocytes: 35.8;Early primary spermatocytes: 90.0;Erythrocyte progenitors: 44.7;Late primary spermatocytes: 42.8;Megakaryocyte progenitors: 39.9;Monocyte progenitors: 43.5;Neutrophil progenitors: 38.5;Oligodendrocytes: 35.3" "Cell type enhanced" "Detected in all" "oligodendrocyte: 49.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 5.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007825, CAB019374" Enhanced NA Yes "Cluster 9: T-regs - Cell cycle regulation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 30: White matter - Myelination" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 65: Non-specific - Cell growth & division" 23 "CAB007825: , CAB019374: " "unprognostic (3.92e-2)" "unprognostic (8.92e-3)" "unprognostic (1.25e-1)" "unprognostic (1.02e-1)" "unprognostic (3.96e-1)" "unprognostic (4.75e-2)" "unprognostic (4.16e-1)" "unprognostic (6.89e-3)" "unprognostic (2.91e-3)" "unprognostic (1.98e-1)" "unprognostic (2.27e-1)" "unprognostic (6.25e-3)" "validated prognostic unfavorable (4.07e-4)" "validated prognostic unfavorable (6.11e-6)" "unprognostic (3.69e-3)" "unprognostic (1.70e-3)" "unprognostic (4.04e-2)" "unprognostic (2.86e-1)" "unprognostic (1.40e-1)" "unprognostic (8.62e-2)" "unprognostic (7.10e-2)" "potential prognostic unfavorable (5.46e-4)" "unprognostic (2.31e-2)" "unprognostic (3.92e-2)" "unprognostic (3.91e-1)" "unprognostic (2.34e-2)" "unprognostic (2.19e-2)" "unprognostic (3.92e-1)" "unprognostic (3.56e-2)" "potential prognostic unfavorable (4.17e-4)" CCNF "FBX1, FBXO1" ENSG00000162063 "Cyclin F" P41002 16 2429394-2458854 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" Cyclin "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 14.1" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 44.7;Megakaryocyte progenitors: 30.1;Monocyte progenitors: 66.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Lung - Mitotic cells (Lung), Prostate - Prostate basal glandular cells, Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA070495, HPA071600" Enhanced Supported Nucleoplasm,Centrosome,Cytosol NA Yes "Cluster 33: Non-specific - ATP binding" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 38: Sub-cortical - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 27: Non-specific - Cell proliferation" 633 Nucleoplasm "Centrosome, Cytosol" "HPA070495: , HPA071600: " "unprognostic (1.90e-2)" "unprognostic (2.09e-3)" "unprognostic (5.51e-2)" "unprognostic (8.90e-3)" "unprognostic (9.49e-3)" "unprognostic (1.41e-1)" "unprognostic (1.67e-1)" "unprognostic (8.59e-2)" "unprognostic (1.11e-1)" "validated prognostic unfavorable (2.95e-9)" "validated prognostic unfavorable (1.71e-4)" "potential prognostic unfavorable (3.45e-4)" "validated prognostic unfavorable (9.57e-7)" "validated prognostic unfavorable (4.82e-5)" "unprognostic (5.43e-3)" "potential prognostic unfavorable (4.23e-4)" "unprognostic (1.14e-1)" "unprognostic (6.84e-3)" "unprognostic (1.44e-1)" "unprognostic (6.43e-2)" "unprognostic (1.38e-3)" "unprognostic (4.57e-3)" "unprognostic (3.87e-2)" "unprognostic (2.91e-2)" "unprognostic (3.83e-1)" "unprognostic (9.64e-2)" "unprognostic (9.84e-2)" "unprognostic (3.35e-2)" "unprognostic (2.48e-2)" "unprognostic (5.50e-3)" CCNG1 CCNG ENSG00000113328 "Cyclin G1" P51959 5 163437569-163446151 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Enterocytes: 235.9;Platelets: 566.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB000350 Supported Supported Nucleoplasm NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 76: Non-specific - Metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 25: Non-specific - Ribosome" "Cluster 47: Platelets - Hemostasis" 22 Nucleoplasm "CAB000350: " "unprognostic (6.07e-3)" "unprognostic (1.57e-1)" "unprognostic (1.84e-1)" "unprognostic (3.37e-2)" "potential prognostic favorable (1.76e-4)" "unprognostic (3.18e-2)" "unprognostic (3.15e-1)" "unprognostic (8.33e-2)" "unprognostic (1.16e-1)" "unprognostic (7.00e-2)" "potential prognostic favorable (4.32e-13)" "unprognostic (1.61e-2)" "unprognostic (9.75e-2)" "unprognostic (1.78e-1)" "unprognostic (4.73e-2)" "unprognostic (5.49e-2)" "unprognostic (9.09e-2)" "unprognostic (3.50e-2)" "unprognostic (1.36e-1)" "unprognostic (2.34e-1)" "unprognostic (6.46e-3)" "unprognostic (1.92e-2)" "unprognostic (2.06e-2)" "unprognostic (1.34e-1)" "unprognostic (9.14e-3)" "unprognostic (1.52e-2)" "unprognostic (3.56e-2)" "unprognostic (1.10e-2)" "unprognostic (3.07e-1)" "unprognostic (1.57e-1)" "unprognostic (8.83e-2)" CCNG2 ENSG00000138764 "Cyclin G2" Q16589 4 77157207-77433388 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Esophageal apical cells: 1325.9" "Cell type enhanced" "Detected in many" "upper rhombic lip: 121.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 21.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 74.9" HPA034684 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 15: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 84: Apical squamous epithelium - Cornification" 2 "Nucleoplasm, Cytosol" "HPA034684: " "unprognostic (3.27e-2)" "unprognostic (3.81e-1)" "unprognostic (7.93e-2)" "unprognostic (6.92e-3)" "unprognostic (5.42e-2)" "unprognostic (1.93e-2)" "unprognostic (1.30e-1)" "unprognostic (2.07e-1)" "unprognostic (3.17e-3)" "unprognostic (5.08e-2)" "validated prognostic favorable (2.80e-10)" "validated prognostic favorable (7.27e-6)" "unprognostic (3.20e-1)" "unprognostic (4.40e-2)" "unprognostic (3.67e-2)" "unprognostic (2.80e-2)" "unprognostic (4.11e-3)" "unprognostic (2.38e-1)" "unprognostic (2.04e-1)" "unprognostic (5.91e-2)" "unprognostic (1.93e-2)" "potential prognostic unfavorable (5.96e-4)" "unprognostic (1.32e-3)" "unprognostic (1.28e-1)" "potential prognostic favorable (2.57e-5)" "unprognostic (9.56e-2)" "unprognostic (8.29e-2)" "unprognostic (2.95e-1)" "unprognostic (1.80e-1)" "unprognostic (7.79e-2)" "unprognostic (4.94e-2)" CCNH "CycH, p34, p37" ENSG00000134480 "Cyclin H" P51946 5 87318416-87412930 "Cancer-related genes, Essential proteins, Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 1358.8;Vascular smooth muscle cells: 887.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019416, HPA044138" Approved Supported Nucleoplasm NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 57: Testis - Spermatogenesis" "Cluster 31: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 103: Non-specific - Basic cellular processes" 80 Nucleoplasm "CAB019416: , HPA044138: " "unprognostic (1.95e-1)" "unprognostic (7.93e-3)" "unprognostic (1.88e-3)" "unprognostic (5.83e-2)" "unprognostic (3.32e-2)" "unprognostic (2.97e-1)" "unprognostic (2.55e-1)" "unprognostic (5.06e-3)" "unprognostic (3.06e-2)" "unprognostic (1.49e-1)" "potential prognostic favorable (5.97e-5)" "unprognostic (3.50e-1)" "unprognostic (7.84e-2)" "unprognostic (2.62e-1)" "unprognostic (2.70e-2)" "unprognostic (5.09e-2)" "unprognostic (6.24e-2)" "unprognostic (9.19e-2)" "unprognostic (2.58e-1)" "potential prognostic unfavorable (8.18e-4)" "unprognostic (2.86e-3)" "unprognostic (2.49e-1)" "potential prognostic unfavorable (7.26e-4)" "unprognostic (8.21e-2)" "unprognostic (1.10e-2)" "unprognostic (1.19e-1)" "unprognostic (3.05e-1)" "unprognostic (2.55e-2)" "unprognostic (7.70e-2)" "unprognostic (2.93e-1)" "unprognostic (1.90e-1)" CCNI CCNI1 ENSG00000118816 "Cyclin I" Q14094 4 77047155-77076309 "Predicted intracellular proteins" Cyclin "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 2300.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Lung - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010206, HPA039853, HPA061470" Uncertain Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 15: Non-specific - Protein processing" 7 "Golgi apparatus" "Nucleoplasm, Nuclear bodies" "CAB010206: , HPA039853: , HPA061470: " "unprognostic (1.44e-3)" "unprognostic (1.17e-1)" "unprognostic (1.94e-1)" "unprognostic (4.14e-2)" "unprognostic (3.69e-2)" "unprognostic (2.27e-1)" "unprognostic (1.70e-1)" "unprognostic (8.54e-3)" "unprognostic (7.03e-2)" "unprognostic (2.65e-3)" "validated prognostic favorable (2.57e-8)" "validated prognostic favorable (1.21e-6)" "unprognostic (1.33e-1)" "unprognostic (2.16e-2)" "unprognostic (5.69e-2)" "unprognostic (2.72e-1)" "unprognostic (2.40e-3)" "unprognostic (1.41e-2)" "unprognostic (3.10e-1)" "unprognostic (6.95e-2)" "unprognostic (2.84e-1)" "unprognostic (1.66e-1)" "unprognostic (4.66e-2)" "unprognostic (2.07e-1)" "unprognostic (5.51e-2)" "unprognostic (1.88e-1)" "unprognostic (1.92e-1)" "unprognostic (4.38e-2)" "unprognostic (1.94e-1)" "unprognostic (1.20e-2)" "unprognostic (1.07e-1)" CCNI2 FLJ16793 ENSG00000205089 "Cyclin I family member 2" Q6ZMN8 5 132747426-132754403 "Predicted intracellular proteins" Cyclin "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.6;intestine: 3.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 10.9;Colonocytes: 9.6;Epididymal clear cells: 44.9;Müller glia: 8.2;Oocytes: 69.1;Plasma cells: 13.1;Renal collecting duct intercalated cells: 20.9" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 8.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 6.7" "Minor Salivary Gland - Minor salivary gland ductal cells, Prostate - Prostate basal glandular cells, Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" HPA056288 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" Yes NA "Cluster 27: T-cells - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 78: Plasma cells - Antibody production & ER-stress response" "Nucleoplasm, Cytosol" "Golgi apparatus" "HPA056288: " "unprognostic (4.92e-2)" "unprognostic (1.66e-1)" "unprognostic (1.52e-2)" "unprognostic (2.03e-1)" "unprognostic (3.10e-3)" "unprognostic (1.58e-1)" "unprognostic (9.48e-2)" "unprognostic (1.08e-1)" "unprognostic (2.14e-1)" "unprognostic (2.87e-1)" "unprognostic (9.49e-3)" "unprognostic (8.97e-2)" "unprognostic (1.39e-2)" "unprognostic (5.90e-2)" "unprognostic (3.79e-1)" "unprognostic (2.92e-1)" CCNJ "bA690P14.1, FLJ10895" ENSG00000107443 "Cyclin J" Q5T5M9 10 96043394-96060870 "Predicted intracellular proteins" Cyclin "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 79.1;Epicardial cells: 34.1;Megakaryocytes: 43.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036531 Approved Approved Cytosol NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 25: Non-specific - Transcription" "Cluster 6: Leukemia - Signal transduction" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 1 Cytosol "HPA036531: " "unprognostic (8.13e-2)" "unprognostic (9.33e-3)" "unprognostic (1.07e-2)" "unprognostic (4.90e-1)" "unprognostic (1.82e-1)" "unprognostic (2.93e-1)" "unprognostic (8.46e-2)" "unprognostic (9.49e-3)" "unprognostic (2.02e-1)" "unprognostic (3.51e-2)" "unprognostic (2.86e-1)" "unprognostic (2.57e-1)" "unprognostic (3.24e-2)" "unprognostic (1.11e-3)" "unprognostic (2.13e-1)" "unprognostic (4.11e-1)" "unprognostic (1.51e-3)" "unprognostic (3.89e-2)" "unprognostic (3.54e-2)" "unprognostic (2.58e-1)" "unprognostic (5.19e-2)" "unprognostic (2.75e-2)" "unprognostic (1.39e-1)" "unprognostic (4.59e-2)" "unprognostic (2.59e-2)" "unprognostic (1.52e-1)" "unprognostic (3.25e-1)" "unprognostic (2.21e-1)" "unprognostic (5.99e-1)" "unprognostic (1.68e-1)" "unprognostic (7.59e-2)" CCNJL FLJ14166 ENSG00000135083 "Cyclin J like" Q8IV13 5 160249083-160345396 "Predicted intracellular proteins" Cyclin "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 85.8;Gonadotrophs: 61.0;Neutrophils: 374.8;Parietal cells: 111.4;Renal collecting duct intercalated cells: 102.0;Sertoli cells: 78.0;Transitional alveolar cells: 71.0" "Cell type enhanced" "Detected in many" "upper rhombic lip: 104.9" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 4 "cerebellum: 38.9" "Group enriched" "Detected in some" 17 "neutrophil: 12.5;NK-cell: 4.0" "Group enriched" "Detected in many" 83 "granulocytes: 12.5;NK-cells: 4.0" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2, Skeletal muscle - Fibroblasts, Stomach - Parietal cells, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA049970 Approved Approved "Nuclear speckles" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 71: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 24: Neutrophils - Innate immunity signal integration" 13 "Nuclear speckles" "HPA049970: " "unprognostic (4.51e-2)" "unprognostic (2.57e-2)" "unprognostic (3.79e-2)" "unprognostic (3.55e-3)" "unprognostic (1.64e-2)" "unprognostic (5.91e-2)" "unprognostic (6.51e-2)" "unprognostic (1.46e-1)" "unprognostic (2.90e-2)" "unprognostic (9.21e-2)" "unprognostic (2.66e-1)" "unprognostic (1.33e-1)" "potential prognostic unfavorable (2.16e-4)" "unprognostic (4.21e-2)" "unprognostic (6.00e-2)" "unprognostic (5.93e-3)" "unprognostic (4.76e-3)" "unprognostic (9.86e-2)" "unprognostic (1.84e-1)" "unprognostic (1.50e-1)" "potential prognostic unfavorable (1.48e-4)" "unprognostic (2.76e-2)" "unprognostic (1.17e-3)" "unprognostic (4.61e-2)" "unprognostic (1.19e-3)" "unprognostic (3.99e-1)" "unprognostic (1.95e-1)" "unprognostic (7.06e-2)" CCNK CPR4 ENSG00000090061 "Cyclin K" O75909 14 99481169-99535044 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Host-virus interaction, Mitosis, Transcription, Transcription regulation" Cyclin "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 96.4" "Cell type enhanced" "Detected in all" "Epicardial cells: 432.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000645, HPA077073" Supported Enhanced Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 24 Nucleoplasm "HPA000645: , HPA077073: " "unprognostic (8.23e-3)" "unprognostic (1.09e-1)" "unprognostic (3.26e-2)" "unprognostic (1.07e-2)" "unprognostic (1.85e-1)" "unprognostic (4.72e-2)" "unprognostic (1.05e-1)" "unprognostic (2.93e-1)" "unprognostic (3.92e-2)" "unprognostic (1.42e-2)" "potential prognostic favorable (4.98e-5)" "unprognostic (1.57e-1)" "unprognostic (1.92e-1)" "potential prognostic unfavorable (3.52e-4)" "unprognostic (4.68e-2)" "unprognostic (1.08e-2)" "unprognostic (1.74e-2)" "unprognostic (1.17e-1)" "unprognostic (6.60e-2)" "unprognostic (2.39e-1)" "unprognostic (5.53e-3)" "unprognostic (9.00e-3)" "unprognostic (1.34e-2)" "unprognostic (2.02e-3)" "unprognostic (1.10e-1)" "potential prognostic unfavorable (6.50e-4)" "unprognostic (1.68e-1)" "unprognostic (1.36e-1)" "unprognostic (3.69e-1)" "unprognostic (8.53e-2)" "unprognostic (1.62e-1)" CCNL1 ania-6a ENSG00000163660 "Cyclin L1" Q9UK58 3 157146508-157160760 "Essential proteins, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" Cyclin Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 874.2;Neutrophils: 1427.1" "Cell type enhanced" "Detected in all" "endothelial cell: 254.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057911 Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 42 "Nucleoplasm, Nuclear bodies" "HPA057911: " "unprognostic (9.28e-2)" "unprognostic (2.29e-1)" "unprognostic (2.00e-2)" "unprognostic (1.19e-1)" "unprognostic (2.53e-1)" "unprognostic (1.63e-1)" "unprognostic (1.08e-1)" "unprognostic (2.26e-1)" "unprognostic (1.52e-1)" "unprognostic (3.28e-1)" "unprognostic (1.06e-1)" "unprognostic (1.79e-1)" "unprognostic (3.00e-1)" "potential prognostic unfavorable (4.93e-5)" "unprognostic (5.01e-2)" "unprognostic (2.09e-1)" "unprognostic (8.42e-2)" "unprognostic (1.28e-2)" "unprognostic (1.14e-1)" "unprognostic (6.85e-2)" "unprognostic (1.41e-2)" "unprognostic (3.92e-2)" "unprognostic (1.15e-2)" "unprognostic (1.81e-1)" "unprognostic (2.66e-2)" "unprognostic (6.93e-2)" "unprognostic (1.52e-1)" "unprognostic (1.46e-1)" "unprognostic (1.81e-1)" "unprognostic (1.08e-1)" "unprognostic (8.72e-2)" CCNL2 "ania-6b, CCNM, CCNS, HLA-ISO, PCEE, SB138" ENSG00000221978 "Cyclin L2" Q96S94 1 1385711-1399335 "Predicted intracellular proteins" "Transcription, Transcription regulation" Cyclin "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053137 Supported Supported "Nucleoplasm,Vesicles,Basal body,Cytosol" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 56: Non-specific - Sensory perception" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 8 Nucleoplasm "Vesicles, Basal body, Cytosol" "HPA053137: " "unprognostic (1.14e-1)" "unprognostic (1.59e-1)" "unprognostic (1.03e-1)" "unprognostic (1.05e-3)" "unprognostic (5.46e-2)" "unprognostic (2.15e-2)" "unprognostic (3.62e-2)" "unprognostic (7.09e-3)" "potential prognostic favorable (6.52e-4)" "unprognostic (5.01e-2)" "unprognostic (7.17e-3)" "unprognostic (8.09e-2)" "unprognostic (7.65e-3)" "unprognostic (3.76e-1)" "unprognostic (1.42e-1)" "unprognostic (1.78e-2)" "unprognostic (1.87e-1)" "unprognostic (1.78e-1)" "unprognostic (1.49e-1)" "unprognostic (1.55e-2)" "unprognostic (1.01e-2)" "unprognostic (1.84e-1)" "unprognostic (1.56e-3)" "potential prognostic unfavorable (5.44e-4)" "unprognostic (1.50e-2)" "potential prognostic favorable (5.50e-4)" "unprognostic (3.73e-2)" "unprognostic (2.06e-1)" "unprognostic (3.10e-1)" "unprognostic (8.41e-2)" "unprognostic (5.63e-2)" CCNO "CCNU, FLJ22422, UDG2, UNG2" ENSG00000152669 "Cyclin O" P22674 5 55231152-55233608 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Cilium biogenesis/degradation" Cyclin "Ciliopathy, Disease variant, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 10.2;pancreas: 11.3;testis: 12.5" "Cell type enriched" "Detected in many" 6 "Respiratory deuterosomal cells: 995.2" "Group enriched" "Detected in many" 6 "choroid plexus epithelial cell: 66.5;ependymal cell: 20.3" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 25.0" "Region enriched" "Detected in all" 5 "choroid plexus: 25.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Pituitary gland - Lactotropes, Testis - Early spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA050090, HPA076641" Uncertain Approved "Nucleoplasm,Nucleoli,Centriolar satellite" NA NA "Cluster 21: Testis - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 4 "Nucleoplasm, Nucleoli" "Centriolar satellite" "HPA050090: , HPA076641: " "unprognostic (4.88e-2)" "unprognostic (1.54e-2)" "unprognostic (1.51e-1)" "unprognostic (4.13e-2)" "unprognostic (1.90e-2)" "unprognostic (1.18e-1)" "unprognostic (7.34e-2)" "unprognostic (1.86e-1)" "unprognostic (1.22e-1)" "unprognostic (7.12e-2)" "unprognostic (2.62e-1)" "unprognostic (8.59e-2)" "unprognostic (1.74e-1)" "unprognostic (5.48e-2)" "unprognostic (2.22e-1)" "unprognostic (3.60e-2)" "unprognostic (1.27e-1)" "unprognostic (4.69e-2)" "unprognostic (5.30e-3)" "unprognostic (1.64e-1)" "potential prognostic favorable (5.52e-4)" "unprognostic (2.33e-1)" "unprognostic (2.45e-1)" "unprognostic (9.41e-3)" CCNP "CNTD2, FLJ13265" ENSG00000105219 "Cyclin P" Q9H8S5 19 40222208-40226697 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "brain: 5.9;kidney: 5.7;liver: 3.0;pituitary gland: 1.5" "Cell type enhanced" "Detected in many" "Early spermatids: 11.6;Fallopian tube ciliated cells: 15.3;Gonadotrophs: 8.6;Loop of henle epithelial cells: 37.1;Oocytes: 32.2;Syncytiotrophoblasts: 13.8;Tuft cells: 23.1" "Cell type enhanced" "Detected in many" "oligodendrocyte precursor cell: 8.0;upper rhombic lip: 10.1" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 7.4" "Immune cell enriched" "Detected in single" 46 "basophil: 4.5" "Lineage enriched" "Detected in single" 46 "granulocytes: 4.5" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 6.0" "Not detected" "Not detected" HPA045615 Uncertain NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 64: Non-specific - Transcription" "Cluster 35: Non-specific - DNA binding" "Cluster 7: Liver cancer - Metabolism" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" "HPA045615: " "unprognostic (3.64e-2)" "unprognostic (4.90e-2)" "unprognostic (2.16e-1)" "unprognostic (3.44e-2)" "unprognostic (8.48e-2)" "unprognostic (6.49e-2)" "unprognostic (1.81e-2)" "unprognostic (2.09e-1)" "unprognostic (2.93e-1)" "unprognostic (2.02e-1)" "unprognostic (7.47e-3)" "unprognostic (2.30e-1)" "unprognostic (6.34e-2)" "unprognostic (1.97e-1)" "unprognostic (1.89e-1)" "unprognostic (3.81e-2)" "unprognostic (1.70e-1)" CCNQ "CycM, FAM58A" ENSG00000262919 "Cyclin Q" Q8N1B3 X 153587925-153600045 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" Cyclin "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 127.6;Syncytiotrophoblasts: 128.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050137, HPA059843" Uncertain Approved Nucleoplasm,Cytosol Yes No "Cluster 22: Eosinophils - Transcription" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" "Nucleoplasm, Cytosol" "HPA050137: , HPA059843: " "unprognostic (1.69e-3)" "unprognostic (4.39e-2)" "unprognostic (4.27e-1)" "unprognostic (3.56e-2)" "unprognostic (1.27e-1)" "unprognostic (3.56e-2)" "unprognostic (3.59e-3)" "unprognostic (2.35e-1)" "unprognostic (9.24e-2)" "potential prognostic unfavorable (6.28e-4)" "unprognostic (7.37e-2)" "potential prognostic unfavorable (8.47e-6)" "unprognostic (2.23e-1)" "unprognostic (3.42e-2)" "unprognostic (3.70e-2)" "unprognostic (2.41e-2)" "unprognostic (1.69e-1)" "unprognostic (6.15e-3)" "unprognostic (1.28e-2)" "unprognostic (3.18e-1)" "unprognostic (1.59e-2)" "unprognostic (1.52e-1)" "unprognostic (6.84e-2)" "unprognostic (7.70e-2)" "unprognostic (4.47e-2)" "unprognostic (9.69e-2)" CCNT1 "CCNT, CYCT1, HIVE1" ENSG00000129315 "Cyclin T1" O60563 12 48688458-48716998 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Host-virus interaction, Transcription, Transcription regulation" Cyclin "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 171.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004892, CAB009016, HPA072012" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 103: Non-specific - Basic cellular processes" 54 Nucleoplasm Cytosol "CAB009016: , HPA004892: , HPA072012: " "unprognostic (1.15e-1)" "unprognostic (3.04e-3)" "unprognostic (9.59e-2)" "unprognostic (2.34e-2)" "unprognostic (1.86e-1)" "unprognostic (3.58e-2)" "unprognostic (5.08e-1)" "unprognostic (6.30e-1)" "unprognostic (1.39e-1)" "unprognostic (1.84e-2)" "potential prognostic favorable (5.59e-5)" "unprognostic (2.75e-3)" "unprognostic (6.97e-2)" "unprognostic (1.75e-3)" "unprognostic (3.34e-1)" "unprognostic (8.64e-2)" "unprognostic (6.68e-2)" "unprognostic (1.99e-2)" "unprognostic (2.32e-1)" "unprognostic (4.54e-2)" "unprognostic (5.74e-2)" "unprognostic (6.91e-2)" "unprognostic (3.01e-3)" "unprognostic (8.42e-2)" "unprognostic (1.14e-1)" "unprognostic (1.01e-1)" "unprognostic (4.46e-2)" "unprognostic (2.60e-1)" "unprognostic (6.02e-2)" "unprognostic (3.42e-2)" "unprognostic (4.23e-2)" CCNT2 ENSG00000082258 "Cyclin T2" O60583 2 134918235-134959342 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Host-virus interaction, Transcription, Transcription regulation" Cyclin "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005559 Supported Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 56: Non-specific - Sensory perception" "Cluster 7: Non-specific - Transcription" 14 "Nucleoplasm, Cytosol" "Plasma membrane" "HPA005559: " "potential prognostic favorable (6.44e-4)" "unprognostic (2.03e-1)" "unprognostic (1.10e-2)" "unprognostic (7.38e-2)" "unprognostic (1.07e-2)" "unprognostic (2.54e-1)" "unprognostic (1.12e-1)" "unprognostic (4.38e-2)" "unprognostic (3.27e-2)" "unprognostic (1.44e-2)" "unprognostic (1.25e-1)" "unprognostic (3.35e-2)" "unprognostic (2.47e-1)" "unprognostic (1.16e-2)" "unprognostic (1.12e-1)" "unprognostic (2.53e-1)" "unprognostic (6.32e-2)" "unprognostic (5.35e-2)" "unprognostic (3.87e-2)" "unprognostic (3.54e-1)" "unprognostic (2.96e-1)" "unprognostic (1.94e-1)" "unprognostic (1.45e-2)" "unprognostic (7.26e-3)" "unprognostic (1.46e-1)" "unprognostic (7.76e-2)" "unprognostic (2.51e-2)" "unprognostic (4.79e-1)" "unprognostic (4.15e-2)" "unprognostic (2.56e-1)" "unprognostic (1.47e-1)" CCNY "C10orf9, CBCP1, CFP1" ENSG00000108100 "Cyclin Y" Q8ND76 10 35247025-35572669 "Predicted intracellular proteins" "Cell cycle, Cell division, Wnt signaling pathway" Cyclin "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 5 "Late spermatids: 6771.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 26.4" "Group enriched" "Detected in all" 5 "dendritic cells: 7.8;granulocytes: 26.4;monocytes: 23.4" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036290, HPA061652" Approved Supported Nucleoplasm,Nucleoli NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 67: Testis - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 14 Nucleoplasm Nucleoli "HPA036290: , HPA061652: " "unprognostic (5.20e-2)" "unprognostic (1.07e-3)" "unprognostic (1.18e-1)" "unprognostic (3.30e-1)" "unprognostic (3.34e-2)" "unprognostic (1.73e-2)" "unprognostic (2.43e-1)" "potential prognostic favorable (3.26e-5)" "unprognostic (1.51e-1)" "unprognostic (3.68e-2)" "potential prognostic favorable (1.01e-4)" "unprognostic (3.89e-2)" "unprognostic (8.71e-2)" "potential prognostic unfavorable (1.94e-5)" "unprognostic (3.89e-2)" "unprognostic (3.10e-1)" "potential prognostic unfavorable (3.07e-4)" "unprognostic (1.95e-1)" "unprognostic (5.48e-1)" "unprognostic (2.37e-1)" "unprognostic (7.62e-3)" "unprognostic (1.56e-1)" "unprognostic (1.15e-1)" "unprognostic (8.16e-2)" "unprognostic (8.73e-2)" "unprognostic (1.01e-1)" "unprognostic (7.73e-2)" "unprognostic (2.34e-2)" "unprognostic (1.50e-1)" "unprognostic (1.57e-1)" "unprognostic (7.80e-2)" CCNYL1 FLJ40432 ENSG00000163249 "Cyclin Y like 1" Q8N7R7 2 207711540-207761839 "Predicted intracellular proteins" "Differentiation, Neurogenesis, Spermatogenesis" Cyclin "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 189.2;Epicardial cells: 200.1;Esophageal apical cells: 170.9;Mesothelial cells: 265.2;Ocular epithelial cells: 181.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast), Lung - Alveolar cells type 2, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046825 Approved Supported "Plasma membrane" Yes No "Cluster 20: Non-specific - DNA binding" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 53: Neurons - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 20: Non-specific - Transcription regulation" 6 "Plasma membrane" "HPA046825: " "unprognostic (1.60e-1)" "unprognostic (2.87e-2)" "unprognostic (1.60e-1)" "unprognostic (9.31e-2)" "unprognostic (2.33e-2)" "unprognostic (2.77e-2)" "unprognostic (2.25e-1)" "unprognostic (2.74e-3)" "unprognostic (3.86e-1)" "unprognostic (1.74e-2)" "potential prognostic favorable (6.09e-7)" "unprognostic (9.30e-2)" "unprognostic (4.65e-2)" "unprognostic (1.49e-3)" "potential prognostic unfavorable (9.65e-4)" "unprognostic (1.53e-1)" "unprognostic (6.12e-3)" "unprognostic (1.25e-2)" "unprognostic (3.65e-2)" "unprognostic (3.85e-2)" "unprognostic (3.32e-1)" "unprognostic (1.95e-2)" "potential prognostic unfavorable (2.85e-5)" "unprognostic (1.04e-1)" "unprognostic (4.90e-2)" "unprognostic (2.24e-1)" "unprognostic (2.72e-1)" "unprognostic (2.64e-2)" "unprognostic (2.49e-2)" "unprognostic (1.26e-1)" "unprognostic (2.88e-3)" CCP110 "CP110, KIAA0419" ENSG00000103540 "Centriolar coiled-coil protein 110" O43303 16 19523811-19553408 "Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 33.2" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 181.7;Fallopian tube ciliated cells: 129.1;Oligodendrocytes: 289.5;Respiratory ciliated cells: 171.3" "Cell type enhanced" "Detected in all" "oligodendrocyte: 318.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pancreas - Endothelial cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039402 Approved Supported "Centriolar satellite" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 80: Oligodendrocytes - Myelination" 57 "Centriolar satellite" "HPA039402: " "unprognostic (4.36e-2)" "unprognostic (3.69e-2)" "unprognostic (1.85e-1)" "unprognostic (3.24e-1)" "unprognostic (3.04e-1)" "unprognostic (3.14e-1)" "unprognostic (7.56e-3)" "unprognostic (3.27e-1)" "potential prognostic unfavorable (6.13e-4)" "validated prognostic favorable (4.33e-5)" "validated prognostic favorable (3.81e-4)" "unprognostic (2.36e-2)" "unprognostic (3.73e-2)" "unprognostic (1.70e-1)" "unprognostic (2.61e-2)" "unprognostic (2.41e-1)" "unprognostic (1.05e-1)" "unprognostic (1.34e-1)" "unprognostic (1.10e-1)" "unprognostic (3.16e-2)" "unprognostic (1.98e-2)" "unprognostic (1.02e-2)" "unprognostic (7.88e-3)" "unprognostic (4.94e-3)" "unprognostic (5.20e-2)" "unprognostic (7.18e-2)" "unprognostic (2.54e-1)" "unprognostic (1.72e-1)" "unprognostic (3.01e-2)" "unprognostic (2.09e-1)" CCPG1 "CPR8, KIAA1254" ENSG00000260916 "Cell cycle progression 1" Q9ULG6 15 55340032-55408510 "Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 258.9;Brain inhibitory neurons: 260.9;Choroid plexus epithelial cells: 113.3;Ependymal cells: 119.6;Loop of henle epithelial cells: 107.7;Neutrophil progenitors: 139.8;Neutrophils: 125.7;Other brain neurons: 220.8;Podocytes: 101.7;Renal collecting duct intercalated cells: 168.4;Renal collecting duct principal cells: 141.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 280.3;neutrophil: 298.2" "Group enriched" "Detected in all" 7 "granulocytes: 298.2;monocytes: 84.8" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Skin - Endothelial cells, Stomach - Chief cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009432, HPA026861" Approved Approved "Endoplasmic reticulum,Golgi apparatus" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 35: Neurons - Synaptic function & neurogenesis" 5 "Golgi apparatus" "Endoplasmic reticulum" "HPA009432: , HPA026861: " "unprognostic (7.88e-2)" "unprognostic (2.40e-2)" "unprognostic (2.49e-1)" "unprognostic (1.77e-2)" "unprognostic (7.22e-2)" "unprognostic (8.68e-3)" "unprognostic (3.30e-1)" "unprognostic (4.27e-3)" "unprognostic (3.82e-1)" "unprognostic (2.27e-3)" "potential prognostic favorable (1.35e-6)" "unprognostic (4.70e-3)" "unprognostic (2.65e-1)" "unprognostic (8.53e-2)" "unprognostic (9.20e-2)" "unprognostic (1.64e-2)" "unprognostic (3.43e-1)" "unprognostic (3.82e-2)" "unprognostic (2.30e-1)" "unprognostic (6.98e-2)" "unprognostic (6.94e-3)" "unprognostic (1.53e-2)" "unprognostic (4.35e-1)" "unprognostic (2.15e-1)" "unprognostic (8.26e-3)" "unprognostic (2.22e-1)" "unprognostic (2.55e-1)" "unprognostic (1.66e-2)" "unprognostic (1.77e-1)" "unprognostic (6.06e-3)" "unprognostic (3.02e-2)" CCR1 "CD191, CKR-1, CMKBR1, MIP1aR, SCYAR1" ENSG00000163823 "C-C motif chemokine receptor 1" P32246 3 46201711-46208313 "CD markers, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 40.1" "Cell type enhanced" "Detected in some" "cDC: 32.3;Extravillous trophoblasts: 126.8;Hofbauer cells: 202.2;Kupffer cells: 282.9;Macrophages: 93.2;Microglia: 38.8;Monocyte progenitors: 36.5;monocytes: 140.5;Neutrophils: 62.8" "Cell type enriched" "Detected in some" 5 "central nervous system macrophage: 44.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in some" 7 "Myeloma: 57.7" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Liver - Kupffer cells, Minor Salivary Gland - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Spleen - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid gland - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 235 "unprognostic (3.66e-1)" "unprognostic (3.92e-1)" "unprognostic (6.55e-2)" "unprognostic (2.60e-1)" "unprognostic (2.10e-1)" "unprognostic (1.97e-1)" "unprognostic (2.92e-2)" "unprognostic (1.64e-1)" "unprognostic (1.59e-1)" "unprognostic (4.80e-2)" "unprognostic (2.53e-1)" "unprognostic (8.00e-2)" "unprognostic (1.80e-1)" "unprognostic (7.18e-2)" "unprognostic (4.61e-2)" "unprognostic (2.09e-1)" "unprognostic (4.04e-3)" "unprognostic (3.75e-2)" "unprognostic (3.87e-1)" "unprognostic (5.96e-2)" "unprognostic (1.89e-1)" "unprognostic (1.11e-1)" "unprognostic (1.17e-1)" "unprognostic (2.26e-1)" "unprognostic (2.04e-2)" "unprognostic (1.52e-1)" "unprognostic (3.77e-3)" "unprognostic (2.31e-1)" "unprognostic (1.97e-2)" "unprognostic (1.31e-1)" "unprognostic (5.78e-2)" CCR10 GPR2 ENSG00000184451 "C-C motif chemokine receptor 10" P46092 17 42678889-42683917 "Cancer-related genes, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 19.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 80.9;Epicardial cells: 61.4;Epididymal principal cells: 30.0;Pericytes: 36.9;Plasma cells: 106.5;Vascular smooth muscle cells: 16.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "plasmacytoid DC: 24.7;T-reg: 72.6" "Group enriched" "Detected in many" 8 "dendritic cells: 24.7;T-cells: 72.6" "Cancer enriched" "Detected in many" 4 "Myeloma: 42.2" "Adrenal gland - Adrenal medulla cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB011684, HPA048007, HPA069188" Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 64: Non-specific - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 67: Plasma cells - Plasma cell differentiation" 2 "Endoplasmic reticulum" "CAB011684: , HPA048007: , HPA069188: " "unprognostic (2.10e-2)" "unprognostic (3.94e-2)" "unprognostic (7.74e-2)" "unprognostic (2.82e-2)" "unprognostic (2.41e-2)" "unprognostic (6.10e-2)" "potential prognostic unfavorable (2.30e-4)" "unprognostic (3.70e-1)" "unprognostic (9.45e-3)" "unprognostic (3.24e-1)" "unprognostic (3.60e-1)" "unprognostic (1.83e-3)" "unprognostic (1.29e-1)" "unprognostic (2.16e-1)" "unprognostic (8.48e-2)" "unprognostic (2.10e-1)" "unprognostic (1.23e-1)" "unprognostic (2.58e-2)" CCR2 "CC-CKR-2, CD192, CKR2, CMKBR2, FLJ78302, MCP-1-R" ENSG00000121807 "C-C motif chemokine receptor 2" P41597 3 46353864-46360940 "CD markers, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "Host-virus interaction, Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 23.1" "Group enriched" "Detected in some" 4 "cDC: 22.8;Monocyte progenitors: 87.5;monocytes: 65.3;pDCs: 73.3;Plasma cells: 32.2" "Cell type enriched" "Detected in single" 60 "leukocyte: 30.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "basophil: 557.4" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in some" 4 "Myeloma: 29.9" "Breast - Plasma cells, Minor Salivary Gland - Plasma cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB003793, HPA063255" Approved Supported "Nucleoli fibrillar center,Plasma membrane" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 20: Myeloma - Immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 1 "Plasma membrane" "Nucleoli fibrillar center" "CAB003793: , HPA063255: " "unprognostic (1.86e-1)" "unprognostic (1.05e-2)" "unprognostic (7.54e-2)" "unprognostic (2.92e-3)" "unprognostic (1.45e-1)" "unprognostic (2.66e-2)" "unprognostic (6.41e-3)" "unprognostic (1.23e-1)" "unprognostic (2.21e-2)" "unprognostic (8.66e-3)" "potential prognostic favorable (5.21e-6)" "unprognostic (1.77e-1)" "unprognostic (8.59e-2)" "unprognostic (1.19e-1)" "unprognostic (4.11e-1)" "unprognostic (1.97e-1)" "unprognostic (3.18e-1)" "unprognostic (7.17e-2)" "unprognostic (1.09e-2)" "unprognostic (4.69e-2)" "unprognostic (2.57e-2)" "unprognostic (1.22e-1)" CCR3 "CC-CKR-3, CD193, CKR3, CMKBR3" ENSG00000183625 "C-C motif chemokine receptor 3" P51677 3 46130890-46266706 "CD markers, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 2.4;lymphoid tissue: 1.5;skeletal muscle: 1.6" "Group enriched" "Detected in some" 6 "Myonuclei: 197.4;Neutrophils: 178.3" "Cell type enhanced" "Detected in single" "central nervous system macrophage: 2.2" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 25 "basophil: 3400.3;eosinophil: 2516.4" "Lineage enriched" "Detected in many" 109 "granulocytes: 3400.3" "Cancer enriched" "Detected in single" 4 "Myeloma: 3.2" "Adipose visceral - Neutrophils, Spleen - Neutrophils_2" "Not detected" "Not detected" "CAB003795, HPA069514" Uncertain Approved "Plasma membrane" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 55: Myocytes - Oxidative muscle function" 3 "Plasma membrane" "CAB003795: , HPA069514: " "unprognostic (1.24e-1)" "unprognostic (1.73e-1)" "unprognostic (2.05e-2)" "unprognostic (4.53e-2)" CCR4 "CC-CKR-4, CD194, ChemR13, CKR4, CMKBR4, k5-5" ENSG00000183813 "C-C motif chemokine receptor 4" P51679 3 32951644-32956349 "CD markers, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 12.1;urinary bladder: 5.1" "Group enriched" "Detected in some" 7 "Innate lymphoid cells: 13.6;Platelets: 32.5;T-cells: 17.6" "Cell type enriched" "Detected in single" 5 "leukocyte: 2.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "T-reg: 60.8" "Lineage enriched" "Detected in many" 41 "T-cells: 60.8" "Cancer enriched" "Detected in some" 4 "lymphoma: 18.7" "Adipose subcutaneous - T-cells, Skin - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA031613 Approved Supported "Plasma membrane" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" 1 "Plasma membrane" "HPA031613: " "unprognostic (4.81e-3)" "unprognostic (5.27e-3)" "unprognostic (3.82e-3)" "unprognostic (2.33e-2)" "unprognostic (2.76e-1)" "unprognostic (1.34e-1)" "potential prognostic favorable (7.29e-7)" "unprognostic (6.70e-3)" "unprognostic (6.17e-2)" "potential prognostic favorable (7.41e-4)" "unprognostic (4.98e-1)" "unprognostic (1.61e-2)" "unprognostic (4.97e-2)" "unprognostic (1.63e-1)" "unprognostic (7.34e-3)" "unprognostic (9.45e-2)" "unprognostic (2.11e-2)" "unprognostic (1.23e-1)" "unprognostic (4.17e-3)" "unprognostic (1.13e-2)" CCR5 "CC-CKR-5, CD195, CKR-5, CKR5, CMKBR5, IDDM22" ENSG00000160791 "C-C motif chemokine receptor 5" P51681 3 46370946-46376206 "CD markers, Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "Host-virus interaction" "G-protein coupled receptor, Host cell receptor for virus entry, Receptor, Transducer" "Diabetes mellitus, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 14.5" "Group enriched" "Detected in some" 4 "cDC: 21.5;Macrophages: 13.5;monocytes: 15.2;pDCs: 15.8;T-cells: 19.4" "Cell type enriched" "Detected in some" 5 "leukocyte: 26.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 40.8" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "lymphoma: 1.5;Myeloma: 1.2" "Lung - T-cells, Prostate - T-cells, Skin - T-cells, Spleen - T-cells, Stomach - T-cells" "Low region specificity" "Detected in all" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 10 "unprognostic (5.40e-2)" "unprognostic (6.68e-3)" "unprognostic (7.59e-2)" "unprognostic (2.58e-2)" "unprognostic (1.57e-1)" "unprognostic (3.78e-1)" "unprognostic (7.60e-2)" "unprognostic (6.10e-2)" "potential prognostic favorable (3.32e-4)" "unprognostic (7.23e-2)" "unprognostic (1.24e-1)" "unprognostic (3.65e-2)" "unprognostic (1.19e-1)" "unprognostic (5.08e-3)" "unprognostic (1.48e-2)" "unprognostic (1.81e-2)" "unprognostic (1.51e-1)" "unprognostic (2.02e-1)" "unprognostic (8.48e-2)" "unprognostic (2.02e-1)" "unprognostic (2.26e-1)" "unprognostic (1.94e-1)" "unprognostic (2.02e-2)" "unprognostic (1.78e-1)" "unprognostic (1.32e-2)" "unprognostic (1.53e-1)" "unprognostic (1.17e-1)" "unprognostic (2.03e-1)" "unprognostic (1.79e-2)" "unprognostic (2.14e-2)" "unprognostic (7.07e-2)" CCR6 "BN-1, CD196, CKR-L3, CMKBR6, DCR2, DRY-6, GPR-CY4, GPR29, STRL22" ENSG00000112486 "C-C motif chemokine receptor 6" P51684 6 167111807-167139141 "CD markers, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 31.7" "Cell type enhanced" "Detected in some" "Astrocytes: 1.2;B-cells: 5.8;Brain excitatory neurons: 2.1;Brain inhibitory neurons: 2.3;Distal convoluted tubule cells: 2.2;Ependymal cells: 6.6;Foveolar cells: 1.8;Innate lymphoid cells: 1.8;Loop of henle epithelial cells: 2.0;Other brain neurons: 2.1;Papillary tip epithelial cells: 1.5;Podocytes: 1.8;Proximal tubule cells: 2.6;Renal collecting duct intercalated cells: 1.5;Renal collecting duct principal cells: 2.4;Renal connecting tubule cells: 1.2;T-cells: 3.0" "Cell type enhanced" "Detected in many" "leukocyte: 26.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "MAIT T-cell: 70.3;memory B-cell: 64.1;memory CD4 T-cell: 27.4;naive B-cell: 73.4;T-reg: 52.1" "Group enriched" "Detected in many" 5 "B-cells: 73.4;T-cells: 70.3" "Cancer enhanced" "Detected in some" "liver cancer: 5.2" "Adipose subcutaneous - T-cells, Lung - T-cells, Prostate - T-cells, Spleen - B-cells (Spleen), Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in single" 7 "basal ganglia: 1.8" "Not detected" "Not detected" "CAB006820, HPA014488" Approved NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 18: Liver cancer - Metabolism" "Cluster 102: Non-specific - Mixed function" 8 "CAB006820: , HPA014488: " "unprognostic (1.26e-1)" "unprognostic (1.45e-1)" "potential prognostic favorable (3.30e-4)" "unprognostic (3.92e-2)" "unprognostic (2.71e-2)" "potential prognostic favorable (1.07e-4)" "unprognostic (7.47e-2)" "unprognostic (3.29e-1)" "unprognostic (4.17e-1)" "unprognostic (3.10e-1)" "potential prognostic favorable (7.48e-4)" "unprognostic (1.92e-1)" "unprognostic (3.69e-2)" "unprognostic (7.23e-2)" "unprognostic (1.32e-1)" "unprognostic (1.07e-1)" "unprognostic (9.65e-3)" "unprognostic (1.18e-1)" "unprognostic (1.05e-1)" "unprognostic (2.32e-2)" "unprognostic (6.21e-2)" CCR7 "BLR2, CD197, CDw197, CMKBR7, EBI1" ENSG00000126353 "C-C motif chemokine receptor 7" P32248 17 40553769-40565472 "Cancer-related genes, CD markers, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 19.7;lymphoid tissue: 78.7" "Cell type enhanced" "Detected in some" "B-cells: 116.3;cDC: 228.4;Cytotrophoblasts: 164.5;Migrating cytotrophoblasts: 143.2;Syncytiotrophoblasts: 575.9;T-cells: 47.1" "Cell type enriched" "Detected in single" 27 "leukocyte: 12.9" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 18.1" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "naive CD4 T-cell: 4611.8" "Lineage enriched" "Detected in all" 4 "T-cells: 4611.8" "Cancer enriched" "Detected in some" 7 "lymphoma: 140.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB003796, HPA031383, HPA074467" Enhanced Enhanced Mitochondria NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 11: White matter - Signal transduction" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 82: Dendritic cells - Antigen presentation" Mitochondria "CAB003796: , HPA031383: , HPA074467: " "unprognostic (1.99e-2)" "unprognostic (2.21e-3)" "unprognostic (2.26e-3)" "potential prognostic favorable (1.71e-5)" "unprognostic (1.70e-1)" "unprognostic (1.42e-1)" "unprognostic (2.03e-2)" "potential prognostic favorable (3.90e-6)" "unprognostic (8.97e-2)" "unprognostic (1.46e-1)" "unprognostic (7.06e-2)" "validated prognostic favorable (5.23e-4)" "validated prognostic favorable (7.77e-4)" "potential prognostic favorable (5.37e-4)" "unprognostic (7.34e-2)" "unprognostic (3.96e-1)" "unprognostic (1.15e-1)" "unprognostic (3.02e-3)" "unprognostic (4.25e-3)" "unprognostic (7.77e-2)" "unprognostic (1.61e-1)" "unprognostic (3.62e-2)" "unprognostic (5.29e-2)" "unprognostic (5.01e-2)" "unprognostic (3.80e-1)" "unprognostic (3.71e-3)" "unprognostic (1.49e-1)" "unprognostic (1.57e-1)" CCR8 "CDw198, CKR-L1, CMKBR8, CMKBRL2, CY6, GPR-CY6, TER1" ENSG00000179934 "C-C motif chemokine receptor 8" P51685 3 39329709-39333680 "CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "lymphoid tissue: 7.2" "Group enriched" "Detected in some" 5 "Cone photoreceptor cells: 4.1;Epicardial cells: 2.3;T-cells: 3.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 6 "T-reg: 25.8" "Lineage enriched" "Detected in single" 32 "T-cells: 25.8" "Group enriched" "Detected in some" 8 "Leukemia: 2.9;lymphoma: 4.4;testis cancer: 2.7" "Skin - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA042383 Enhanced NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 80: Thymus - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" "HPA042383: " "unprognostic (2.09e-1)" "unprognostic (1.38e-1)" "unprognostic (3.80e-1)" "unprognostic (1.10e-3)" "unprognostic (1.01e-1)" "unprognostic (6.27e-2)" "unprognostic (5.04e-2)" "unprognostic (4.96e-3)" "unprognostic (1.99e-2)" CCR9 "CDw199, GPR-9-6, GPR28" ENSG00000173585 "C-C motif chemokine receptor 9" P51686 3 45884425-45903174 "CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "lymphoid tissue: 120.8" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 17.7;Epicardial cells: 9.1;Innate lymphoid cells: 8.3;Myonuclei: 8.8;NK-cells: 16.5;Retinal horizontal cells: 4.0;Rod photoreceptor cells: 4.2;T-cells: 4.6;Thymocytes: 31.3" "Cell type enriched" "Detected in single" 15 "fibroblast: 8.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 6 "memory B-cell: 24.3;naive B-cell: 15.7;T-reg: 8.2" "Group enriched" "Detected in many" 43 "B-cells: 24.3;T-cells: 8.2" "Cancer enriched" "Detected in single" 8 "Leukemia: 6.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB006839, HPA066879" Uncertain Approved "Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 80: Thymus - Adaptive immune response" "Cluster 30: White matter - Myelination" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" 1 "Plasma membrane" "Endoplasmic reticulum" "CAB006839: , HPA066879: " CCRL2 "ACKR5, CKRX, CRAM-A, CRAM-B, HCR" ENSG00000121797 "C-C motif chemokine receptor like 2" O00421 3 46407166-46412997 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "cDC: 22.4;Enterocytes: 16.0;Goblet cells: 19.8;Hofbauer cells: 38.6;Kupffer cells: 18.4;Macrophages: 36.3;monocytes: 116.2;Neutrophils: 65.8;Paneth cells: 15.5;Platelets: 19.8" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 2.4;endothelial cell: 7.7;vascular associated smooth muscle cell: 3.1" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 25.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA043238 Approved Supported "Plasma membrane,Primary cilium,Primary cilium tip" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" "Plasma membrane" "Primary cilium, Primary cilium tip" "HPA043238: " "unprognostic (8.87e-2)" "unprognostic (3.06e-1)" "unprognostic (3.77e-2)" "unprognostic (1.76e-1)" "unprognostic (1.41e-2)" "unprognostic (4.57e-2)" "unprognostic (3.34e-1)" "unprognostic (1.56e-1)" "unprognostic (1.14e-1)" "unprognostic (1.02e-1)" "unprognostic (3.90e-3)" "unprognostic (1.09e-2)" "unprognostic (7.25e-2)" "unprognostic (8.77e-2)" "unprognostic (1.57e-1)" "unprognostic (2.92e-1)" "unprognostic (2.89e-2)" "unprognostic (5.84e-2)" "unprognostic (1.57e-1)" "unprognostic (3.40e-2)" "unprognostic (2.23e-1)" "unprognostic (9.76e-2)" "unprognostic (1.40e-2)" "unprognostic (5.83e-2)" "unprognostic (1.34e-2)" "unprognostic (1.07e-1)" "potential prognostic favorable (3.87e-4)" "unprognostic (7.30e-2)" "unprognostic (9.46e-2)" "unprognostic (4.12e-1)" "unprognostic (2.91e-1)" CCS ENSG00000173992 "Copper chaperone for superoxide dismutase" O14618 11 66593153-66606019 "Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Bergmann glia: 170.0;Hepatocytes: 194.0;Platelets: 287.6" "Cell type enhanced" "Detected in all" "Bergmann glia: 206.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008672, HPA040026, HPA044090" Approved NA NA 660000 "Cluster 29: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 55: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 47: Platelets - Hemostasis" 8 "CAB008672: , HPA040026: , HPA044090: " "unprognostic (1.55e-1)" "unprognostic (1.65e-1)" "unprognostic (3.04e-2)" "unprognostic (2.04e-1)" "unprognostic (9.90e-3)" "unprognostic (4.12e-1)" "unprognostic (1.66e-1)" "unprognostic (1.30e-1)" "unprognostic (1.71e-2)" "unprognostic (2.27e-1)" "potential prognostic favorable (3.24e-5)" "unprognostic (2.75e-2)" "potential prognostic favorable (2.28e-6)" "unprognostic (3.30e-2)" "potential prognostic favorable (2.08e-4)" "unprognostic (2.59e-1)" "unprognostic (1.75e-2)" "unprognostic (4.39e-2)" "unprognostic (9.93e-2)" "unprognostic (2.01e-1)" "unprognostic (9.80e-2)" "unprognostic (2.24e-2)" "unprognostic (2.86e-1)" "unprognostic (3.56e-1)" "unprognostic (5.37e-2)" "unprognostic (2.41e-1)" "unprognostic (1.59e-1)" "unprognostic (2.43e-1)" "unprognostic (1.48e-1)" "unprognostic (2.20e-1)" "unprognostic (2.04e-1)" CCSAP "C1orf96, CSAP, FLJ41471" ENSG00000154429 "Centriole, cilia and spindle associated protein" Q6IQ19 1 229321011-229343294 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 30.8;retina: 23.9" "Cell type enhanced" "Detected in many" "Retinal bipolar cells: 88.6;Syncytiotrophoblasts: 151.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028402, HPA043443" Enhanced Supported NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 45: Non-specific - Nuclear processes" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." "HPA028402: , HPA043443: " "unprognostic (1.25e-1)" "unprognostic (9.70e-2)" "unprognostic (2.96e-1)" "unprognostic (7.60e-2)" "unprognostic (1.31e-2)" "unprognostic (1.31e-1)" "unprognostic (3.86e-2)" "unprognostic (5.46e-2)" "potential prognostic unfavorable (3.41e-4)" "unprognostic (3.75e-3)" "unprognostic (6.92e-2)" "unprognostic (7.76e-3)" "potential prognostic unfavorable (6.33e-4)" "unprognostic (6.89e-2)" "unprognostic (2.04e-3)" "unprognostic (4.33e-2)" "unprognostic (3.25e-1)" "unprognostic (4.10e-1)" "unprognostic (2.70e-1)" "unprognostic (1.06e-1)" "unprognostic (5.20e-3)" "unprognostic (2.64e-1)" "unprognostic (1.24e-1)" "unprognostic (1.38e-1)" "unprognostic (1.18e-1)" "unprognostic (1.07e-1)" "unprognostic (4.05e-1)" "unprognostic (4.15e-2)" "unprognostic (1.07e-1)" CCSER1 "FAM190A, KIAA1680" ENSG00000184305 "Coiled-coil serine rich protein 1" Q9C0I3 4 90127394-91605295 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "retina: 3.1;testis: 2.4" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 4297.3;Cone photoreceptor cells: 3833.9;Distal convoluted tubule cells: 3461.7;Loop of henle epithelial cells: 1920.5;Renal connecting tubule cells: 2913.9;Sertoli cells: 4099.4;Somatotrophs: 2711.8;Tuft cells: 4438.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Gallbladder cancer: 1.6" "Adipose subcutaneous - Endothelial cells, Adrenal gland - Adrenal medulla cells, Heart muscle - Cardiomyocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041880, HPA054709" Uncertain NA NA "Cluster 42: Retina - Visual perception" "Cluster 37: Neurons - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 6 "HPA041880: , HPA054709: " "unprognostic (1.63e-2)" "unprognostic (5.65e-3)" "unprognostic (1.81e-2)" "unprognostic (1.28e-1)" "unprognostic (1.60e-1)" "unprognostic (2.48e-2)" "unprognostic (1.20e-1)" CCSER2 "FAM190B, KIAA1128" ENSG00000107771 "Coiled-coil serine rich protein 2" Q9H7U1 10 84328586-84518521 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 13 "Early spermatids: 2729.8;Late spermatids: 8992.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037481, HPA037482" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 1: T-cells - Unknown function" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 45: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 14 "Nucleoplasm, Cytosol" "HPA037481: , HPA037482: " "unprognostic (1.35e-3)" "unprognostic (1.17e-3)" "unprognostic (3.84e-2)" "unprognostic (1.78e-2)" "unprognostic (2.66e-1)" "unprognostic (2.21e-2)" "potential prognostic favorable (5.71e-5)" "unprognostic (4.61e-2)" "unprognostic (1.25e-2)" "potential prognostic favorable (1.93e-8)" "unprognostic (2.22e-3)" "unprognostic (1.78e-1)" "unprognostic (1.04e-1)" "unprognostic (6.32e-2)" "unprognostic (2.28e-1)" "unprognostic (2.35e-3)" "unprognostic (5.10e-2)" "unprognostic (5.31e-3)" "potential prognostic unfavorable (5.20e-4)" "unprognostic (3.47e-2)" "unprognostic (2.95e-2)" "unprognostic (1.59e-1)" "unprognostic (5.46e-3)" "unprognostic (8.41e-2)" "unprognostic (3.75e-1)" "unprognostic (5.44e-2)" "unprognostic (1.57e-1)" "unprognostic (6.41e-2)" "unprognostic (1.55e-1)" CCT2 Cctb ENSG00000166226 "Chaperonin containing TCP1 subunit 2" P78371 12 69585426-69601570 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Chaperone, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 1560.5;Late primary spermatocytes: 1325.4;Late spermatids: 576.2;Oocytes: 598.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003197, HPA003198" Enhanced Supported "Cytosol,Connecting piece,Mid piece,Principal piece" NA NA 3400000 "Cluster 13: Non-specific - Mitochondria" "Cluster 39: Testis - Nuclear processes" "Cluster 21: Non-specific - Metabolism" "Cluster 38: Non-specific - Transcription" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 326 Cytosol "Connecting piece, Mid piece, Principal piece" "HPA003197: , HPA003198: " "unprognostic (4.26e-3)" "unprognostic (1.04e-2)" "unprognostic (5.76e-2)" "unprognostic (1.64e-1)" "unprognostic (9.90e-3)" "unprognostic (9.90e-3)" "unprognostic (6.64e-2)" "unprognostic (1.57e-1)" "unprognostic (1.37e-3)" "unprognostic (4.03e-2)" "potential prognostic favorable (6.49e-6)" "unprognostic (3.26e-2)" "unprognostic (7.82e-2)" "validated prognostic unfavorable (4.42e-10)" "validated prognostic unfavorable (6.95e-6)" "potential prognostic unfavorable (1.40e-4)" "unprognostic (3.14e-3)" "unprognostic (1.71e-1)" "unprognostic (2.60e-1)" "unprognostic (8.83e-2)" "unprognostic (2.69e-1)" "unprognostic (2.85e-2)" "unprognostic (1.96e-2)" "unprognostic (1.83e-3)" "unprognostic (2.45e-2)" "unprognostic (6.46e-2)" "unprognostic (2.11e-1)" "unprognostic (1.91e-1)" "unprognostic (2.15e-1)" "unprognostic (1.80e-1)" "unprognostic (2.23e-1)" CCT3 "Cctg, TRIC5" ENSG00000163468 "Chaperonin containing TCP1 subunit 3" P49368 1 156308968-156367873 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Chaperone, Hydrolase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006543, HPA074177" Approved Approved "Vesicles,Plasma membrane,Cytosol" NA NA 2100000 "Cluster 13: Non-specific - Mitochondria" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 215 Cytosol "Vesicles, Plasma membrane" "HPA006543: , HPA074177: " "unprognostic (3.50e-3)" "unprognostic (6.39e-2)" "unprognostic (9.43e-2)" "unprognostic (4.69e-3)" "unprognostic (1.83e-2)" "unprognostic (2.00e-1)" "unprognostic (8.50e-3)" "potential prognostic favorable (5.55e-4)" "unprognostic (1.40e-3)" "unprognostic (2.22e-3)" "unprognostic (1.26e-1)" "unprognostic (5.84e-2)" "potential prognostic unfavorable (1.40e-8)" "validated prognostic unfavorable (6.64e-7)" "validated prognostic unfavorable (3.09e-4)" "potential prognostic unfavorable (4.66e-4)" "unprognostic (8.79e-3)" "unprognostic (9.89e-2)" "unprognostic (2.18e-1)" "unprognostic (1.41e-1)" "unprognostic (1.14e-1)" "unprognostic (1.68e-1)" "unprognostic (2.50e-1)" "unprognostic (3.65e-2)" "unprognostic (2.82e-1)" "unprognostic (4.81e-2)" "unprognostic (2.08e-1)" "unprognostic (3.22e-1)" "unprognostic (8.44e-2)" "unprognostic (3.77e-1)" "unprognostic (3.43e-1)" CCT4 Cctd ENSG00000115484 "Chaperonin containing TCP1 subunit 4" P50991 2 61868085-61888671 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Chaperone, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 573.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029349 Supported Supported Nucleoplasm,Cytosol NA NA 2100000 "Cluster 33: Non-specific - ATP binding" "Cluster 54: Non-specific - Ribosome" "Cluster 55: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 75: Non-specific - Chaperones and protein folding" 167 Cytosol Nucleoplasm "HPA029349: " "unprognostic (2.94e-2)" "unprognostic (1.81e-3)" "unprognostic (2.00e-2)" "unprognostic (2.41e-2)" "unprognostic (3.03e-1)" "unprognostic (1.46e-1)" "unprognostic (1.80e-1)" "unprognostic (5.29e-2)" "unprognostic (4.00e-3)" "unprognostic (4.81e-3)" "potential prognostic favorable (1.33e-6)" "unprognostic (5.48e-2)" "potential prognostic unfavorable (2.54e-4)" "validated prognostic unfavorable (9.30e-13)" "validated prognostic unfavorable (6.67e-6)" "potential prognostic unfavorable (5.57e-5)" "unprognostic (1.91e-3)" "unprognostic (6.64e-2)" "unprognostic (3.98e-1)" "unprognostic (2.42e-2)" "unprognostic (1.04e-2)" "unprognostic (2.19e-2)" "unprognostic (1.20e-2)" "unprognostic (6.90e-2)" "unprognostic (4.73e-2)" "unprognostic (1.59e-1)" "unprognostic (2.15e-1)" "unprognostic (2.45e-1)" "unprognostic (2.54e-1)" "unprognostic (3.63e-2)" "unprognostic (2.31e-1)" CCT5 KIAA0098 ENSG00000150753 "Chaperonin containing TCP1 subunit 5" P48643 5 10249929-10266389 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Chaperone, Hydrolase" "Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 421.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Macrophages, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002238, HPA005958, CAB006271" Enhanced Approved "Mid piece,Principal piece,Annulus" NA NA 1600000 "Cluster 40: Monocytes - Innate immune response" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 29: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 209 "Mid piece" "Principal piece, Annulus" "CAB006271: , HPA002238: , HPA005958: " "potential prognostic unfavorable (2.23e-4)" "unprognostic (1.52e-3)" "unprognostic (1.55e-2)" "unprognostic (2.42e-1)" "unprognostic (3.20e-1)" "unprognostic (3.14e-1)" "unprognostic (2.42e-1)" "unprognostic (3.37e-2)" "unprognostic (2.11e-2)" "unprognostic (4.88e-2)" "unprognostic (1.16e-3)" "unprognostic (2.15e-2)" "potential prognostic unfavorable (3.29e-7)" "validated prognostic unfavorable (2.22e-10)" "validated prognostic unfavorable (6.74e-6)" "validated prognostic unfavorable (2.76e-4)" "validated prognostic unfavorable (1.92e-4)" "unprognostic (1.04e-1)" "unprognostic (2.22e-1)" "unprognostic (1.49e-2)" "unprognostic (9.72e-2)" "potential prognostic unfavorable (1.36e-4)" "unprognostic (1.45e-2)" "unprognostic (1.44e-3)" "unprognostic (9.83e-3)" "unprognostic (1.27e-1)" "unprognostic (1.03e-1)" "unprognostic (1.04e-1)" "unprognostic (4.64e-1)" "unprognostic (2.32e-1)" "unprognostic (2.01e-2)" CCT6A "CCT6, Cctz, HTR3, TCP20, TCPZ, TTCP20" ENSG00000146731 "Chaperonin containing TCP1 subunit 6A" P40227 7 56051685-56063989 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Chaperone, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA042996, HPA045576, HPA049949" Supported Approved Cytosol NA NA 4200000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 67: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 212 Cytosol "HPA042996: , HPA045576: , HPA049949: " "potential prognostic unfavorable (5.17e-4)" "unprognostic (9.25e-3)" "unprognostic (1.14e-1)" "unprognostic (2.02e-2)" "unprognostic (1.19e-1)" "unprognostic (2.12e-1)" "unprognostic (2.11e-1)" "unprognostic (2.25e-1)" "unprognostic (5.60e-3)" "unprognostic (3.35e-3)" "potential prognostic favorable (1.52e-6)" "unprognostic (1.52e-1)" "potential prognostic unfavorable (2.45e-4)" "validated prognostic unfavorable (1.55e-5)" "validated prognostic unfavorable (1.40e-8)" "potential prognostic unfavorable (1.61e-6)" "unprognostic (4.08e-3)" "unprognostic (1.54e-2)" "unprognostic (1.42e-1)" "unprognostic (1.13e-1)" "unprognostic (3.69e-1)" "unprognostic (5.16e-2)" "unprognostic (1.46e-2)" "unprognostic (9.45e-2)" "unprognostic (3.74e-2)" "unprognostic (2.06e-1)" "unprognostic (1.49e-1)" "unprognostic (7.95e-2)" "unprognostic (2.25e-1)" "unprognostic (5.27e-2)" "unprognostic (3.24e-2)" CCT6B "Cctz2, TSA303" ENSG00000132141 "Chaperonin containing TCP1 subunit 6B" Q92526 17 34927859-34981078 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 23 "testis: 117.9" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 148.0;Early spermatids: 332.7;Epicardial cells: 134.2;Late primary spermatocytes: 1211.8;Late spermatids: 225.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA042996, HPA045576, HPA049949" Uncertain Approved Cytosol NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 57: Testis - Spermatogenesis" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 82 Cytosol "HPA042996: , HPA045576: , HPA049949: " "unprognostic (3.98e-2)" "unprognostic (1.42e-1)" "unprognostic (1.57e-1)" "unprognostic (3.51e-3)" "unprognostic (2.24e-1)" "unprognostic (1.08e-1)" "unprognostic (8.71e-2)" "unprognostic (1.64e-1)" "unprognostic (2.25e-1)" "unprognostic (1.08e-1)" "potential prognostic favorable (3.37e-8)" "unprognostic (6.33e-3)" "potential prognostic favorable (3.47e-4)" "unprognostic (1.21e-3)" "unprognostic (8.45e-3)" "unprognostic (3.06e-1)" "unprognostic (2.50e-1)" "unprognostic (2.98e-1)" "unprognostic (1.35e-1)" "unprognostic (2.04e-2)" "unprognostic (4.00e-2)" "unprognostic (8.84e-3)" "unprognostic (1.78e-1)" "unprognostic (2.36e-2)" "unprognostic (1.02e-2)" "unprognostic (4.05e-2)" "unprognostic (1.14e-1)" "unprognostic (5.40e-2)" "unprognostic (1.13e-1)" "unprognostic (1.45e-3)" "unprognostic (4.69e-2)" CCT7 "Ccth, Nip7-1" ENSG00000135624 "Chaperonin containing TCP1 subunit 7" Q99832 2 73233420-73253021 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Chaperone, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 360.1;Late primary spermatocytes: 740.1;Late spermatids: 360.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008425 Approved Approved Cytosol NA NA 4100000 "Cluster 13: Non-specific - Mitochondria" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 17: Non-specific - RNA processing" 220 Cytosol "HPA008425: " "unprognostic (1.53e-2)" "unprognostic (1.90e-3)" "unprognostic (1.23e-1)" "unprognostic (7.49e-2)" "unprognostic (3.40e-1)" "unprognostic (4.35e-1)" "unprognostic (1.72e-1)" "unprognostic (7.67e-2)" "unprognostic (9.37e-3)" "unprognostic (2.50e-2)" "unprognostic (2.47e-3)" "unprognostic (1.38e-1)" "unprognostic (1.02e-2)" "validated prognostic unfavorable (4.95e-8)" "validated prognostic unfavorable (2.96e-9)" "potential prognostic unfavorable (5.01e-5)" "unprognostic (1.81e-2)" "unprognostic (2.09e-2)" "unprognostic (3.20e-2)" "unprognostic (1.19e-1)" "unprognostic (1.54e-1)" "unprognostic (1.73e-1)" "unprognostic (3.46e-1)" "unprognostic (4.45e-1)" "unprognostic (2.12e-1)" "unprognostic (2.48e-1)" "unprognostic (1.90e-1)" "unprognostic (1.08e-1)" "unprognostic (4.52e-1)" "unprognostic (1.41e-1)" "unprognostic (6.05e-2)" CCT8 "C21orf112, Cctq, PRED71" ENSG00000156261 "Chaperonin containing TCP1 subunit 8" P50990 21 29055805-29073797 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Chaperone, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 497.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018520, HPA021051, HPA029426" Enhanced Uncertain "Nucleoplasm,Cytosol,Connecting piece,Mid piece,Principal piece,End piece" NA No 3500000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 17: Non-specific - RNA processing" 143 "Nucleoplasm, Connecting piece, End piece" "Cytosol, Mid piece, Principal piece" "HPA018520: , HPA021051: , HPA029426: " "unprognostic (2.60e-2)" "unprognostic (1.15e-3)" "unprognostic (9.16e-2)" "unprognostic (1.39e-2)" "unprognostic (2.66e-2)" "unprognostic (1.68e-2)" "unprognostic (2.05e-1)" "unprognostic (1.19e-1)" "potential prognostic unfavorable (1.33e-4)" "unprognostic (5.65e-2)" "potential prognostic favorable (3.08e-4)" "unprognostic (1.74e-1)" "unprognostic (4.60e-3)" "validated prognostic unfavorable (3.02e-7)" "validated prognostic unfavorable (5.27e-5)" "validated prognostic unfavorable (1.00e-4)" "validated prognostic unfavorable (2.79e-4)" "unprognostic (1.57e-1)" "unprognostic (4.10e-1)" "unprognostic (3.21e-2)" "unprognostic (3.84e-1)" "unprognostic (1.45e-2)" "unprognostic (1.51e-1)" "unprognostic (2.32e-1)" "unprognostic (1.03e-2)" "unprognostic (1.96e-1)" "unprognostic (4.70e-1)" "unprognostic (2.43e-1)" "unprognostic (1.12e-1)" "unprognostic (3.59e-1)" "unprognostic (2.47e-1)" CCT8L2 CESK1 ENSG00000198445 "Chaperonin containing TCP1 subunit 8 like 2" Q96SF2 22 16590751-16592810 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 202 "testis: 20.2" "Group enriched" "Detected in some" 57 "Early spermatids: 214.6;Late primary spermatocytes: 71.1;Late spermatids: 105.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" CCZ1 "C7orf28A, CCZ1A, CGI-43" ENSG00000122674 "CCZ1 homolog, vacuolar protein trafficking and biogenesis associated" P86791 7 5898725-5926550 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "HPA045114, HPA050006" Uncertain Enhanced Vesicles NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 67: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 7 Vesicles "HPA045114: , HPA050006: " "unprognostic (1.54e-2)" "unprognostic (1.05e-2)" "unprognostic (8.71e-3)" "unprognostic (3.58e-1)" "unprognostic (5.92e-2)" "unprognostic (3.51e-1)" "unprognostic (7.80e-2)" "unprognostic (5.56e-2)" "unprognostic (6.59e-2)" "unprognostic (2.15e-2)" "unprognostic (1.06e-2)" "unprognostic (1.89e-1)" "unprognostic (8.46e-3)" "potential prognostic unfavorable (3.24e-4)" "unprognostic (1.56e-1)" "unprognostic (8.28e-3)" "unprognostic (4.78e-1)" "unprognostic (1.96e-1)" "unprognostic (5.47e-1)" "unprognostic (1.94e-3)" "unprognostic (9.34e-2)" "unprognostic (2.73e-2)" "unprognostic (1.57e-1)" "unprognostic (3.20e-3)" "unprognostic (1.82e-1)" "unprognostic (1.58e-1)" "unprognostic (1.88e-1)" "unprognostic (1.51e-1)" "unprognostic (1.16e-1)" "unprognostic (2.84e-2)" CCZ1B "C7orf28B, DKFZP586I1023, H_NH0577018.2, MGC19819" ENSG00000146574 "CCZ1 homolog B, vacuolar protein trafficking and biogenesis associated" P86790 7 6794134-6826770 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA045114, HPA050006" Uncertain Enhanced Vesicles NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 67: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 28 Vesicles "HPA045114: , HPA050006: " "unprognostic (7.78e-3)" "potential prognostic unfavorable (3.34e-4)" "unprognostic (3.70e-2)" "unprognostic (2.35e-1)" "unprognostic (1.75e-2)" "unprognostic (1.40e-2)" "potential prognostic unfavorable (5.37e-5)" "unprognostic (1.50e-2)" "unprognostic (1.69e-1)" "unprognostic (6.20e-3)" "unprognostic (4.40e-2)" "unprognostic (9.40e-2)" "potential prognostic unfavorable (2.23e-5)" "unprognostic (7.15e-3)" "unprognostic (1.05e-1)" "unprognostic (7.65e-2)" "unprognostic (2.91e-1)" "unprognostic (1.45e-1)" "unprognostic (5.21e-2)" "unprognostic (6.53e-2)" "unprognostic (3.11e-3)" "unprognostic (2.43e-1)" "unprognostic (2.81e-1)" "unprognostic (9.00e-2)" "unprognostic (1.67e-1)" "unprognostic (3.73e-1)" "unprognostic (1.24e-1)" "unprognostic (3.37e-2)" "potential prognostic unfavorable (4.44e-4)" CD101 "IGSF2, V7" ENSG00000134256 "CD101 molecule" Q93033 1 117001750-117036552 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.4;intestine: 5.9;lung: 6.3" "Cell type enhanced" "Detected in many" "Breast lactating cells: 14.3;cDC: 8.3;Epicardial cells: 9.1;Kupffer cells: 12.3;Mesothelial cells: 8.9;monocytes: 12.0;Neutrophil progenitors: 25.3;Salivary basal cells: 16.9;Salivary myoepithelial cells: 13.2;T-cells: 14.8" "Cell type enhanced" "Detected in many" "leukocyte: 18.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "eosinophil: 97.1" "Group enriched" "Detected in many" 18 "dendritic cells: 33.8;granulocytes: 97.1;monocytes: 53.4" "Low cancer specificity" "Detected in some" "Stomach - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA049527, HPA057763" Approved Uncertain Mitochondria NA NA 5000000 "Cluster 25: Non-specific - Unknown function" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 53: Neurons - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 1 Mitochondria "HPA049527: , HPA057763: " "unprognostic (1.58e-1)" "unprognostic (3.42e-2)" "unprognostic (8.00e-2)" "unprognostic (2.93e-1)" "unprognostic (2.36e-1)" "unprognostic (2.94e-3)" "unprognostic (1.58e-1)" "unprognostic (2.50e-1)" "unprognostic (2.79e-3)" "unprognostic (2.06e-2)" "unprognostic (1.44e-1)" "unprognostic (2.28e-1)" "unprognostic (2.90e-1)" "unprognostic (1.68e-1)" "unprognostic (2.09e-2)" "unprognostic (3.23e-1)" "unprognostic (3.42e-1)" CD109 "CPAMD7, DKFZp762L1111, FLJ38569" ENSG00000156535 "CD109 molecule" Q6YHK3 6 73695785-73828316 "CD markers, Plasma proteins, Predicted membrane proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 17 "parathyroid gland: 310.7" "Cell type enhanced" "Detected in many" "Ependymal cells: 127.3;Hematopoietic stem cells: 391.1;Hofbauer cells: 172.0;Macrophages: 103.5;Megakaryocyte progenitors: 118.2;Megakaryocyte-Erythroid progenitors: 200.6;monocytes: 122.3;Ocular epithelial cells: 192.0;Platelets: 136.9;Thymic myoid cells: 140.0;Thymocytes: 139.7;Vascular endothelial cells: 115.5" "Group enriched" "Detected in many" 6 "astrocyte: 107.9;endothelial cell: 116.4;ependymal cell: 153.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Endothelial cells, Liver - Hepatic stellate cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008992, HPA015723" Enhanced Supported "Plasma membrane,Cytosol" NA NA 130000000 "Cluster 69: Parathyroid gland - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 5 "Plasma membrane" Cytosol "HPA008992: , HPA015723: " "unprognostic (1.68e-3)" "unprognostic (1.66e-1)" "unprognostic (2.46e-1)" "unprognostic (1.58e-1)" "unprognostic (3.81e-2)" "unprognostic (6.52e-3)" "unprognostic (1.34e-2)" "potential prognostic unfavorable (3.99e-4)" "unprognostic (2.36e-1)" "unprognostic (2.64e-1)" "unprognostic (9.11e-3)" "unprognostic (1.08e-1)" "unprognostic (1.20e-1)" "unprognostic (2.29e-3)" "unprognostic (2.23e-2)" "potential prognostic unfavorable (1.21e-6)" "unprognostic (6.69e-3)" "unprognostic (7.59e-2)" "unprognostic (1.43e-1)" "unprognostic (3.05e-1)" "unprognostic (2.11e-2)" "potential prognostic unfavorable (8.91e-4)" "unprognostic (1.52e-3)" "unprognostic (7.55e-2)" "unprognostic (2.45e-2)" "unprognostic (3.70e-3)" "unprognostic (1.88e-1)" "potential prognostic unfavorable (2.81e-4)" "unprognostic (1.86e-1)" "unprognostic (1.31e-1)" "unprognostic (6.75e-2)" CD14 ENSG00000170458 "CD14 molecule" P08571 5 140631728-140633700 "Cancer-related genes, CD markers, Human disease related genes, Plasma proteins, Predicted secreted proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 425.8" "Cell type enriched" "Detected in many" 4 "Hofbauer cells: 6153.6" "Cell type enriched" "Detected in many" 12 "central nervous system macrophage: 162.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 3500.8" "Group enriched" "Detected in all" 6 "granulocytes: 935.1;monocytes: 3500.8" "Cancer enhanced" "Detected in many" "breast cancer: 11.9;head and neck cancer: 9.9" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Hepatocytes, Pancreas - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Spleen - Macrophages, Stomach - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001887, HPA002127, CAB033631, CAB072865, CAB072866" Enhanced Approved Vesicles "Secreted to blood" Immunity NA NA 2750000000 2300000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 76: Non-specific - Metabolism" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 27: Breast cancer - Unknown function" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 7 Vesicles "CAB033631: , CAB072865: , CAB072866: , HPA001887: , HPA002127: " "unprognostic (1.54e-1)" "unprognostic (2.46e-1)" "unprognostic (4.70e-1)" "unprognostic (2.39e-1)" "unprognostic (6.55e-2)" "unprognostic (3.82e-2)" "unprognostic (1.46e-2)" "unprognostic (5.41e-2)" "unprognostic (2.31e-1)" "unprognostic (1.17e-1)" "unprognostic (3.04e-3)" "unprognostic (4.92e-1)" "unprognostic (1.09e-2)" "unprognostic (2.78e-3)" "potential prognostic favorable (5.22e-5)" "unprognostic (1.08e-1)" "unprognostic (3.00e-2)" "potential prognostic unfavorable (5.06e-4)" "unprognostic (6.18e-2)" "unprognostic (4.14e-3)" "unprognostic (2.80e-1)" "unprognostic (4.39e-2)" "unprognostic (5.05e-2)" "unprognostic (1.14e-1)" "unprognostic (4.35e-2)" "unprognostic (4.57e-2)" "unprognostic (1.54e-1)" "unprognostic (2.37e-2)" "unprognostic (2.77e-3)" "unprognostic (7.17e-2)" "unprognostic (8.64e-2)" CD151 "PETA-3, RAPH, SFA-1, TSPAN24" ENSG00000177697 "CD151 molecule (Raph blood group)" P48509 11 832887-839831 "Blood group antigen proteins, CD markers, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Host-virus interaction" "Blood group antigen" "Deafness, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 806.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 611.9;Breast myoepithelial cells: 466.7;Decidual stromal cells: 669.6;Extravillous trophoblasts: 570.3;Platelets: 593.9" "Group enriched" "Detected in all" 4 "endothelial cell: 72.8;pericyte: 165.3;vascular associated smooth muscle cell: 190.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Minor Salivary Gland - Minor salivary glandular cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002428, HPA011906" Supported NA NA 18000 "Cluster 25: Non-specific - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 12: Non-specific - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 62: Smooth muscle cells - Muscle contraction" 38 "CAB002428: , HPA011906: " "unprognostic (2.89e-1)" "unprognostic (1.93e-1)" "unprognostic (1.06e-2)" "unprognostic (3.13e-1)" "unprognostic (1.61e-1)" "unprognostic (1.08e-1)" "unprognostic (9.24e-3)" "potential prognostic unfavorable (9.68e-5)" "unprognostic (1.95e-2)" "unprognostic (5.89e-2)" "unprognostic (5.69e-3)" "unprognostic (1.67e-2)" "unprognostic (1.33e-1)" "potential prognostic unfavorable (2.34e-4)" "unprognostic (1.76e-2)" "unprognostic (7.63e-2)" "unprognostic (3.47e-2)" "potential prognostic unfavorable (1.51e-5)" "unprognostic (3.53e-2)" "unprognostic (7.28e-2)" "unprognostic (1.25e-1)" "unprognostic (1.09e-3)" "unprognostic (3.12e-1)" "unprognostic (2.39e-1)" "unprognostic (5.69e-2)" "unprognostic (4.82e-2)" "unprognostic (2.46e-2)" "unprognostic (1.57e-2)" "unprognostic (1.08e-1)" "unprognostic (3.02e-2)" "unprognostic (1.50e-1)" CD160 "BY55, NK1, NK28" ENSG00000117281 "CD160 molecule" O95971 1 145719471-145739288 "CD markers, Predicted secreted proteins" "Adaptive immunity, Angiogenesis, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 4.8;brain: 15.2;intestine: 4.4;liver: 4.7;lymphoid tissue: 12.7" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 27.5;Epicardial cells: 29.6;Late spermatids: 19.3;NK-cells: 111.5;T-cells: 36.7" "Cell type enriched" "Detected in many" 9 "leukocyte: 30.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "gdT-cell: 108.0;MAIT T-cell: 44.6;memory CD8 T-cell: 73.0;naive CD8 T-cell: 83.2;NK-cell: 86.1" "Group enriched" "Detected in all" 8 "NK-cells: 86.1;T-cells: 108.0" "Low cancer specificity" "Detected in many" "Liver - NK-cells (Liver)" "Not detected" "Not detected" "Secreted to blood" Receptor NA NA 3130000 "Cluster 15: NK-cells - Unknown function" "Cluster 27: Cerebellum - Synaptic function" "Cluster 15: Non-specific - Transcription" "Cluster 59: Leukemia - T-cell receptor" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 8 "unprognostic (7.98e-2)" "unprognostic (1.61e-1)" "unprognostic (5.65e-2)" "unprognostic (5.74e-2)" "unprognostic (4.54e-2)" "unprognostic (2.34e-1)" "unprognostic (1.03e-1)" "unprognostic (4.90e-2)" "unprognostic (1.36e-1)" "unprognostic (1.62e-2)" "unprognostic (3.73e-2)" "unprognostic (5.94e-2)" CD163 "M130, MM130, SCARI1" ENSG00000177575 "CD163 molecule" Q86VB7 12 7470811-7503893 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Acute phase, Inflammatory response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 224.8" "Cell type enhanced" "Detected in many" "Hofbauer cells: 359.6;Kupffer cells: 2041.6;Macrophages: 893.3;Monocyte progenitors: 188.9;monocytes: 738.4;Neutrophils: 539.2" "Cell type enriched" "Detected in some" 6 "central nervous system macrophage: 33.5" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 100.8" "Region enhanced" "Detected in all" "thalamus: 112.0" "Group enriched" "Detected in many" 11 "classical monocyte: 76.1;myeloid DC: 65.3" "Group enriched" "Detected in many" 40 "dendritic cells: 65.3;monocytes: 76.1" "Cancer enriched" "Detected in single" 9 "lymphoma: 6.1" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Lung - Macrophages, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Spleen - Macrophages, Stomach - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB002432, HPA046404, HPA051974" Enhanced Supported "Plasma membrane" "Secreted to blood" "Acute phase" NA NA 903000000 340000000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 2 "Plasma membrane" "CAB002432: , HPA046404: , HPA051974: " "unprognostic (3.36e-1)" "unprognostic (3.58e-1)" "unprognostic (2.24e-1)" "unprognostic (7.01e-2)" "unprognostic (2.11e-1)" "unprognostic (4.46e-2)" "unprognostic (2.02e-3)" "unprognostic (3.39e-2)" "unprognostic (1.37e-1)" "unprognostic (2.19e-1)" "unprognostic (2.67e-2)" "unprognostic (2.50e-1)" "unprognostic (5.02e-1)" "unprognostic (1.84e-1)" "unprognostic (3.71e-2)" "unprognostic (8.19e-2)" "potential prognostic unfavorable (7.35e-5)" "unprognostic (2.18e-2)" "unprognostic (1.23e-1)" "unprognostic (5.10e-2)" "unprognostic (3.43e-1)" "unprognostic (8.41e-2)" "unprognostic (1.31e-1)" "unprognostic (3.06e-2)" "unprognostic (5.84e-3)" "unprognostic (1.95e-2)" "unprognostic (9.01e-2)" "unprognostic (2.05e-1)" "unprognostic (1.07e-2)" "unprognostic (1.40e-1)" "unprognostic (2.67e-2)" CD163L1 "CD163B, M160, SCARI2, WC1" ENSG00000177675 "CD163 molecule like 1" Q9NR16 12 7346685-7479897 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 20.6;lymphoid tissue: 30.0" "Cell type enhanced" "Detected in many" "Breast lactating cells: 83.3;Hofbauer cells: 136.1;Kupffer cells: 152.7;Macrophages: 218.0;monocytes: 34.8;Neutrophils: 163.8;Retinal ganglion cells: 69.5" "Cell type enhanced" "Detected in many" "lower rhombic lip: 50.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Macrophages, Minor Salivary Gland - Macrophages, Spleen - Macrophages, Testis - Early spermatids" HPA015663 Enhanced Approved Nucleoplasm,Centrosome,Cytosol "Intracellular and membrane" "No annotated function" NA NA 170000 "Cluster 66: Lymphoid tissue - Immune response" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 72: Neuronal - Signal transduction" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" "Centrosome, Cytosol" Nucleoplasm "HPA015663: " "unprognostic (1.51e-1)" "potential prognostic unfavorable (1.07e-4)" "unprognostic (2.40e-1)" "unprognostic (1.47e-2)" "unprognostic (1.49e-1)" "unprognostic (1.22e-1)" "unprognostic (4.18e-2)" "unprognostic (5.16e-3)" "unprognostic (1.93e-1)" "unprognostic (1.60e-1)" "unprognostic (4.27e-1)" "unprognostic (2.20e-2)" "unprognostic (2.55e-1)" "unprognostic (2.34e-2)" "unprognostic (2.53e-1)" "unprognostic (1.64e-2)" "unprognostic (3.12e-1)" "unprognostic (1.86e-1)" "unprognostic (4.37e-2)" "unprognostic (1.59e-2)" "unprognostic (2.29e-1)" "unprognostic (3.62e-2)" "unprognostic (3.60e-2)" "unprognostic (5.89e-2)" "unprognostic (2.20e-1)" "unprognostic (5.96e-3)" CD164 "DFNA66, MGC-24, MUC-24" ENSG00000135535 "CD164 molecule" Q04900 6 109366514-109382467 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Myogenesis" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Parietal cells: 731.9;Syncytiotrophoblasts: 886.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010636 Approved "Intracellular and membrane" "Cell adhesion" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 77: Intestine - Digestion" "Cluster 21: Non-specific - Metabolism" "Cluster 28: Non-specific - Nuclear processes" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." 3 "HPA010636: " "unprognostic (1.70e-2)" "potential prognostic unfavorable (9.91e-4)" "unprognostic (2.61e-3)" "unprognostic (3.17e-2)" "unprognostic (8.70e-2)" "unprognostic (3.42e-3)" "unprognostic (9.90e-2)" "potential prognostic unfavorable (2.60e-4)" "unprognostic (1.52e-2)" "unprognostic (5.28e-3)" "potential prognostic favorable (1.09e-7)" "unprognostic (1.05e-2)" "unprognostic (1.10e-1)" "potential prognostic unfavorable (7.57e-4)" "unprognostic (6.16e-3)" "unprognostic (2.44e-1)" "unprognostic (2.66e-1)" "unprognostic (1.63e-1)" "unprognostic (3.82e-2)" "unprognostic (1.80e-1)" "unprognostic (1.95e-2)" "unprognostic (8.61e-2)" "unprognostic (1.99e-1)" "unprognostic (3.84e-2)" "unprognostic (1.46e-1)" "unprognostic (2.83e-2)" "unprognostic (1.60e-1)" "unprognostic (4.96e-2)" "unprognostic (6.51e-2)" "unprognostic (2.69e-1)" "unprognostic (1.60e-1)" CD164L2 ENSG00000174950 "CD164 molecule like 2" Q6UWJ8 1 27379176-27383333 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 19.3;fallopian tube: 28.3;salivary gland: 12.7" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 61.6;Epididymal efferent duct ciliated cells: 112.1;Esophageal apical cells: 55.2;Esophageal basal cells: 27.0;Esophageal suprabasal cells: 46.9;Fallopian tube ciliated cells: 197.3;Respiratory ciliated cells: 153.8" "Cell type enhanced" "Detected in some" "deep-layer near-projecting: 4.7;ependymal cell: 16.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in some" "thalamus: 2.6" HPA062915 Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 17: Choroid plexus - Cilium" "Cluster 27: Breast cancer - Unknown function" "Cluster 107: Ciliated cells - Cilia assembly & function" Cytosol "Plasma membrane" "HPA062915: " "unprognostic (7.78e-2)" "unprognostic (8.26e-2)" "unprognostic (9.25e-2)" "unprognostic (1.45e-2)" "potential prognostic favorable (4.13e-4)" "unprognostic (7.51e-2)" "potential prognostic favorable (1.61e-4)" "unprognostic (7.96e-2)" "unprognostic (6.09e-2)" "unprognostic (2.96e-2)" "unprognostic (1.14e-1)" "unprognostic (2.26e-1)" "unprognostic (2.11e-2)" "unprognostic (2.44e-1)" "unprognostic (3.39e-1)" "unprognostic (1.19e-1)" "unprognostic (4.81e-2)" CD177 "HNA2A, NB1, PRV1" ENSG00000204936 "CD177 molecule" 19 43353686-43363172 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 270.4;intestine: 154.8" "Group enriched" "Detected in some" 5 "Colonocytes: 379.3;Neutrophil progenitors: 425.3;Neutrophils: 751.5" "Cell type enriched" "Detected in single" 46 "fibroblast: 22.8" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 52.2" "Region enhanced" "Detected in many" "cerebral cortex: 17.6" "Immune cell enriched" "Detected in some" 7 "neutrophil: 8.8" "Lineage enriched" "Detected in many" 7 "granulocytes: 8.8" "Cancer enriched" "Detected in many" 20 "Rhabdoid: 55.5" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophils_2, Prostate - Prostate glandular cells, Skeletal muscle - Neutrophils, Spleen - Neutrophils_2, Stomach - Neutrophils, Thyroid gland - Neutrophils" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041820, HPA046601, HPA077640" Enhanced "Intracellular and membrane" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 15: Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 5: Rhabdoid - Unknown function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" "HPA041820: , HPA046601: , HPA077640: " "unprognostic (9.70e-2)" "unprognostic (5.60e-2)" "unprognostic (2.55e-1)" "unprognostic (1.19e-3)" "unprognostic (3.79e-3)" "unprognostic (1.59e-2)" "unprognostic (7.13e-2)" "unprognostic (2.32e-2)" "unprognostic (4.19e-1)" "unprognostic (3.52e-1)" "unprognostic (3.29e-1)" "unprognostic (8.16e-2)" "unprognostic (9.35e-2)" "unprognostic (1.31e-1)" "unprognostic (9.96e-2)" "unprognostic (1.30e-1)" "unprognostic (3.79e-2)" "unprognostic (9.05e-2)" "unprognostic (7.19e-2)" "unprognostic (2.46e-1)" "unprognostic (2.56e-1)" "unprognostic (2.41e-1)" "unprognostic (1.98e-2)" CD180 "LY64, Ly78, RP105" ENSG00000134061 "CD180 molecule" Q99467 5 67179613-67196799 "CD markers, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 21.8" "Cell type enhanced" "Detected in some" "B-cells: 47.7;Breast lactating cells: 57.6;cDC: 17.7;Epicardial cells: 22.7;Hofbauer cells: 150.3;Kupffer cells: 34.8;Macrophages: 26.6;Monocyte progenitors: 33.2;monocytes: 19.0;pDCs: 28.9;Plasma cells: 50.2" "Group enriched" "Detected in some" 5 "central nervous system macrophage: 17.2;leukocyte: 5.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 77.2;naive B-cell: 79.2" "Group enriched" "Detected in many" 25 "B-cells: 79.2;dendritic cells: 23.5;monocytes: 34.7" "Group enriched" "Detected in some" 4 "lymphoma: 19.2;Myeloma: 11.7" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Plasma cells, Colon - Macrophages, Heart muscle - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Skeletal muscle - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA003740 Enhanced Approved "Nucleoplasm,Nucleoli,Plasma membrane,Mitotic spindle" Yes NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 3 "Plasma membrane" "Nucleoplasm, Nucleoli, Mitotic spindle" "HPA003740: " "unprognostic (1.08e-1)" "unprognostic (4.66e-2)" "unprognostic (1.85e-1)" "unprognostic (3.27e-2)" "unprognostic (3.61e-1)" "unprognostic (2.06e-2)" "unprognostic (1.15e-1)" "unprognostic (6.05e-3)" "unprognostic (1.29e-1)" "unprognostic (1.91e-1)" "unprognostic (3.30e-1)" "unprognostic (1.16e-2)" "unprognostic (4.80e-2)" "unprognostic (3.87e-2)" "unprognostic (9.02e-2)" "unprognostic (1.06e-1)" "unprognostic (3.29e-1)" "unprognostic (2.07e-1)" "unprognostic (5.95e-2)" "unprognostic (2.19e-2)" "unprognostic (1.21e-1)" "unprognostic (2.83e-2)" "unprognostic (3.22e-1)" CD19 ENSG00000177455 "CD19 molecule" P15391 16 28931965-28939342 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" "Adaptive immunity, Immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "intestine: 31.2;lymphoid tissue: 70.8" "Cell type enhanced" "Detected in some" "B-cells: 83.9;Early primary spermatocytes: 7.7;Early spermatids: 21.4;Epicardial cells: 6.8;Epididymal efferent duct ciliated cells: 10.1;Late primary spermatocytes: 39.0;Late spermatids: 9.4;Plasma cells: 19.5" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 1.0;endothelial cell: 1.2;leukocyte: 1.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 81 "memory B-cell: 138.6;naive B-cell: 172.5" "Lineage enriched" "Detected in many" 90 "B-cells: 172.5" "Group enriched" "Detected in some" 13 "Leukemia: 37.8;lymphoma: 71.1" "Lung - B-cells (Lung), Spleen - B-cells (Spleen), Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB016110 Enhanced NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 6: Leukemia - Signal transduction" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 7 "CAB016110: " "unprognostic (3.23e-1)" "potential prognostic favorable (7.75e-5)" "unprognostic (3.31e-2)" "unprognostic (1.01e-1)" "potential prognostic favorable (1.36e-5)" "unprognostic (3.05e-1)" "potential prognostic favorable (1.29e-4)" "unprognostic (4.37e-2)" "unprognostic (3.62e-1)" "unprognostic (3.03e-1)" "unprognostic (1.93e-1)" "unprognostic (2.59e-2)" "unprognostic (2.18e-1)" "unprognostic (2.38e-1)" CD1A CD1 ENSG00000158477 "CD1a molecule" P06126 1 158254424-158258269 "CD markers, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "lymphoid tissue: 296.0" "Cell type enriched" "Detected in some" 4 "cDC: 57.6" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 8.5" "Not detected" "Not detected" "Group enriched" "Detected in some" 25 "classical monocyte: 6.4;intermediate monocyte: 4.2;memory B-cell: 10.2;myeloid DC: 11.4;naive B-cell: 5.3" "Group enriched" "Detected in many" 37 "B-cells: 10.2;dendritic cells: 11.4;monocytes: 6.4" "Cancer enriched" "Detected in single" 16 "Leukemia: 13.5" "Not detected" "Not detected" "CAB000009, HPA010734" Enhanced NA NA 21000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 80: Thymus - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 82: Dendritic cells - Antigen presentation" 1 "CAB000009: , HPA010734: " "unprognostic (1.19e-1)" "potential prognostic favorable (6.98e-5)" "unprognostic (2.53e-2)" "unprognostic (1.02e-3)" "unprognostic (1.40e-2)" "unprognostic (2.09e-2)" "unprognostic (2.40e-1)" "unprognostic (1.16e-1)" "unprognostic (1.20e-1)" "unprognostic (5.10e-2)" "unprognostic (2.35e-2)" "unprognostic (2.55e-2)" "unprognostic (1.36e-1)" "unprognostic (2.40e-1)" CD1B CD1 ENSG00000158485 "CD1b molecule" P29016 1 158327951-158331531 "CD markers, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 155 "lymphoid tissue: 492.2" "Cell type enriched" "Detected in some" 17 "cDC: 82.7" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 6 "myeloid DC: 19.2" "Lineage enriched" "Detected in many" 6 "dendritic cells: 19.2" "Cancer enriched" "Detected in single" 487 "Leukemia: 48.7" "Low region specificity" "Detected in all" HPA021824 Approved Approved "Golgi apparatus,Vesicles,Cytosol" NA NA 30000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 80: Thymus - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 82: Dendritic cells - Antigen presentation" 21 "Golgi apparatus, Vesicles" Cytosol "HPA021824: " "unprognostic (2.65e-3)" "unprognostic (3.00e-3)" "unprognostic (3.68e-2)" "unprognostic (9.40e-2)" "unprognostic (2.78e-1)" CD1C CD1 ENSG00000158481 "CD1c molecule" P29017 1 158289923-158294774 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "lymphoid tissue: 121.2" "Cell type enriched" "Detected in some" 15 "cDC: 625.6" "Cell type enriched" "Detected in single" 20 "leukocyte: 2.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "memory B-cell: 84.5;myeloid DC: 325.4" "Group enriched" "Detected in many" 8 "B-cells: 84.5;dendritic cells: 325.4" "Group enriched" "Detected in some" 46 "Leukemia: 5.3;lymphoma: 7.2" "Prostate - T-cells, Spleen - B-cells (Spleen), Thyroid gland - T-cells" HPA068359 Approved "Endoplasmic reticulum,Golgi apparatus,Vesicles" NA NA 73000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 80: Thymus - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 82: Dendritic cells - Antigen presentation" 2 "Golgi apparatus, Vesicles" "Endoplasmic reticulum" "HPA068359: " "unprognostic (9.36e-3)" "unprognostic (2.16e-3)" "unprognostic (1.12e-3)" "unprognostic (6.73e-3)" "unprognostic (1.02e-2)" "unprognostic (1.73e-1)" "unprognostic (3.13e-2)" "potential prognostic favorable (9.51e-5)" "unprognostic (3.24e-2)" "unprognostic (2.33e-1)" "unprognostic (5.38e-2)" "unprognostic (5.15e-2)" "unprognostic (1.35e-3)" "unprognostic (3.40e-2)" "unprognostic (9.56e-2)" "unprognostic (2.10e-1)" "unprognostic (8.10e-2)" "unprognostic (4.92e-2)" "unprognostic (3.67e-1)" "unprognostic (6.64e-2)" "unprognostic (2.01e-2)" "unprognostic (3.33e-1)" "unprognostic (8.25e-2)" "unprognostic (3.31e-1)" "unprognostic (1.34e-1)" "unprognostic (8.04e-2)" CD1D ENSG00000158473 "CD1d molecule" P15813 1 158178030-158186427 "Cancer-related genes, CD markers, Predicted membrane proteins" "Immunity, Innate immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 9.6;liver: 8.5;lymphoid tissue: 13.2" "Cell type enhanced" "Detected in some" "B-cells: 13.1;cDC: 52.9;Kupffer cells: 47.1;Macrophages: 20.2;Monocyte progenitors: 50.8;monocytes: 53.8;Neutrophils: 11.6" "Group enriched" "Detected in some" 6 "central nervous system macrophage: 2.0;leukocyte: 4.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 6 "classical monocyte: 139.1;intermediate monocyte: 63.8;myeloid DC: 139.4" "Group enriched" "Detected in many" 8 "dendritic cells: 139.4;monocytes: 139.1" "Cancer enhanced" "Detected in some" "Leukemia: 3.3;lymphoma: 2.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB016107, HPA072662" Enhanced Supported "Endoplasmic reticulum" NA NA 240000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 8: Immune cells - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" "Endoplasmic reticulum" "CAB016107: , HPA072662: " "unprognostic (1.37e-3)" "unprognostic (1.42e-1)" "unprognostic (4.25e-2)" "unprognostic (4.24e-2)" "unprognostic (1.82e-2)" "unprognostic (3.93e-2)" "unprognostic (7.10e-2)" "unprognostic (3.40e-1)" "unprognostic (3.09e-3)" "potential prognostic favorable (9.72e-5)" "unprognostic (3.34e-1)" "unprognostic (4.01e-2)" "unprognostic (2.09e-2)" "unprognostic (2.57e-2)" "unprognostic (1.97e-1)" "unprognostic (8.45e-2)" "unprognostic (1.97e-2)" CD1E ENSG00000158488 "CD1e molecule" P15812 1 158353696-158357553 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 68 "lymphoid tissue: 895.4" "Cell type enriched" "Detected in some" 9 "cDC: 352.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 14 "myeloid DC: 62.6" "Lineage enriched" "Detected in many" 14 "dendritic cells: 62.6" "Cancer enriched" "Detected in single" 433 "Leukemia: 66.8" "Skin - Langerhans cells" "Not detected" "Not detected" "HPA057769, HPA070634" Uncertain Supported "Nucleoli,Golgi apparatus" "Intracellular and membrane" Immunity NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 80: Thymus - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 82: Dendritic cells - Antigen presentation" "Golgi apparatus" Nucleoli "HPA057769: , HPA070634: " "unprognostic (3.02e-1)" "unprognostic (5.66e-3)" "unprognostic (1.69e-3)" "potential prognostic favorable (9.58e-5)" "unprognostic (9.36e-2)" "unprognostic (2.47e-2)" "potential prognostic favorable (1.69e-5)" "unprognostic (7.09e-3)" "unprognostic (7.12e-2)" "unprognostic (1.12e-1)" "unprognostic (1.36e-3)" "unprognostic (3.02e-1)" "unprognostic (8.28e-2)" "unprognostic (2.16e-1)" "unprognostic (2.84e-1)" "unprognostic (1.56e-1)" "unprognostic (1.24e-1)" "unprognostic (3.09e-2)" "unprognostic (2.42e-1)" "unprognostic (3.01e-1)" "unprognostic (2.05e-2)" "unprognostic (4.71e-2)" "unprognostic (5.37e-1)" "unprognostic (9.43e-2)" "unprognostic (1.56e-1)" CD2 SRBC ENSG00000116824 "CD2 molecule" P06729 1 116754430-116769229 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "lymphoid tissue: 232.5" "Group enriched" "Detected in some" 6 "Innate lymphoid cells: 131.5;NK-cells: 142.3;T-cells: 525.2" "Cell type enriched" "Detected in some" 242 "leukocyte: 345.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 6 "gdT-cell: 422.7;MAIT T-cell: 403.9;memory CD4 T-cell: 611.9;memory CD8 T-cell: 713.9;naive CD4 T-cell: 317.2;naive CD8 T-cell: 487.5;NK-cell: 1110.8;T-reg: 656.9" "Group enriched" "Detected in all" 10 "NK-cells: 1110.8;T-cells: 713.9" "Group enriched" "Detected in some" 66 "Leukemia: 11.8;lymphoma: 12.5" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Minor Salivary Gland - T-cells, Pancreas - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Skin - T-cells, Spleen - T-cells, Stomach - T-cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB002430, HPA003883" Enhanced Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" 15 "Plasma membrane" "Nucleoplasm, Golgi apparatus" "CAB002430: , HPA003883: " "unprognostic (7.62e-3)" "unprognostic (1.57e-3)" "unprognostic (3.33e-2)" "unprognostic (3.23e-3)" "unprognostic (8.33e-2)" "unprognostic (9.51e-2)" "unprognostic (3.03e-2)" "unprognostic (9.52e-2)" "potential prognostic favorable (3.95e-4)" "unprognostic (3.29e-1)" "unprognostic (1.17e-1)" "unprognostic (1.18e-1)" "unprognostic (3.54e-2)" "unprognostic (8.61e-3)" "unprognostic (4.64e-3)" "unprognostic (3.01e-3)" "unprognostic (6.71e-2)" "unprognostic (3.71e-1)" "unprognostic (1.95e-1)" "unprognostic (1.74e-2)" "unprognostic (4.93e-2)" "unprognostic (4.31e-2)" "unprognostic (1.94e-1)" "unprognostic (3.87e-1)" "unprognostic (1.35e-2)" "unprognostic (1.49e-1)" "potential prognostic favorable (1.87e-4)" "unprognostic (1.35e-1)" "unprognostic (5.64e-2)" "unprognostic (1.52e-1)" "unprognostic (1.15e-1)" CD200 "MOX1, MOX2, MRC, OX-2" ENSG00000091972 "CD200 molecule" P41217 3 112332347-112362812 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 63.9" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 85.7;Endometrial glandular cells: 103.0;Epicardial cells: 261.5;Epididymal basal cells: 214.7;Lymphatic endothelial cells: 96.8;Mesothelial cells: 145.7;Other brain neurons: 101.6;Syncytiotrophoblasts: 92.2;Vascular endothelial cells: 96.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "memory B-cell: 30.8;naive B-cell: 83.8" "Lineage enriched" "Detected in many" 23 "B-cells: 83.8" "Cancer enhanced" "Detected in many" "Neuroblastoma: 21.0;skin cancer: 31.2" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Breast - Breast myoepithelial cells, Kidney - Endothelial cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031149 Approved NA NA "Cluster 34: B-cells - Unknown function" "Cluster 65: Brain - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 69: Skin cancer - ECM organization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 1 "HPA031149: " "unprognostic (8.08e-2)" "unprognostic (3.72e-1)" "unprognostic (9.64e-2)" "unprognostic (1.38e-1)" "unprognostic (1.97e-1)" "unprognostic (9.31e-2)" "unprognostic (5.98e-2)" "unprognostic (2.69e-2)" "unprognostic (1.08e-1)" "unprognostic (1.26e-1)" "potential prognostic favorable (1.29e-4)" "unprognostic (3.00e-2)" "unprognostic (1.93e-2)" "unprognostic (7.66e-2)" "unprognostic (4.69e-2)" "unprognostic (6.45e-2)" "unprognostic (9.30e-2)" "unprognostic (7.03e-2)" "unprognostic (4.07e-2)" "unprognostic (8.57e-2)" "unprognostic (4.54e-2)" "unprognostic (1.34e-2)" "unprognostic (4.49e-1)" "unprognostic (7.27e-2)" "unprognostic (1.50e-1)" "unprognostic (2.80e-1)" "unprognostic (5.61e-2)" "unprognostic (3.87e-3)" "unprognostic (2.23e-1)" "unprognostic (2.00e-1)" "unprognostic (3.51e-2)" CD200R1 "CD200R, HCRTR2, MOX2R, OX2R" ENSG00000163606 "CD200 receptor 1" Q8TD46 3 112921205-112975103 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 7.5" "Cell type enhanced" "Detected in many" "cDC: 66.7;Conjunctival goblet cells: 19.4;Hofbauer cells: 83.7;Innate lymphoid cells: 30.5;Kupffer cells: 16.4;Macrophages: 34.1;Mast cells: 35.2;Neutrophil progenitors: 78.8;Platelets: 42.5;T-cells: 29.6" "Cell type enhanced" "Detected in many" "leukocyte: 35.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 4 "basophil: 235.9" "Lineage enriched" "Detected in all" 10 "granulocytes: 235.9" "Cancer enhanced" "Detected in some" "cervical cancer: 10.0" "Adrenal gland - Macrophages" HPA068512 Supported "Plasma membrane" "Intracellular and membrane" Receptor NA NA 110000 "Cluster 46: Basophils - Proteolysis" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 23: Choroid plexus - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 1 "Plasma membrane" "HPA068512: " "unprognostic (1.20e-1)" "unprognostic (5.98e-3)" "unprognostic (2.48e-1)" "unprognostic (1.57e-1)" "unprognostic (1.14e-1)" "unprognostic (4.85e-2)" "unprognostic (4.43e-2)" "potential prognostic favorable (6.71e-7)" "unprognostic (1.79e-1)" "unprognostic (2.56e-1)" "unprognostic (2.79e-1)" "unprognostic (8.54e-3)" "unprognostic (9.44e-3)" "unprognostic (3.76e-1)" CD200R1L "CD200R2, CD200RLa" ENSG00000206531 "CD200 receptor 1 like" Q6Q8B3 3 112815709-112846864 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 26 "testis: 2.6" "Cell type enhanced" "Detected in some" "Early spermatids: 19.9;Late primary spermatocytes: 29.3;Late spermatids: 86.1" "Cell type enriched" "Detected in single" 42 "deep-layer near-projecting: 32.2" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 386 "basophil: 85.4" "Lineage enriched" "Detected in single" 459 "granulocytes: 85.4" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 57: Testis - Spermatogenesis" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 1 CD207 "CLEC4K, Langerin" ENSG00000116031 "CD207 molecule" Q9UJ71 2 70830211-70835816 "CD markers, Disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 82.8" "Group enriched" "Detected in some" 4 "cDC: 6.8;Macrophages: 16.2;Retinal pigment epithelial cells: 4.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 10.7" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 12 "myeloid DC: 1.1" "Lineage enriched" "Detected in single" 12 "dendritic cells: 1.1" "Cancer enhanced" "Detected in some" "Bone cancer: 1.3" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002222, HPA011216" Enhanced Uncertain Cytosol No NA "Cluster 37: Skin - Keratinization" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 82: Dendritic cells - Antigen presentation" 8 Cytosol "CAB002222: , HPA011216: " "unprognostic (3.24e-1)" "unprognostic (1.29e-2)" "unprognostic (1.97e-1)" "unprognostic (7.47e-2)" "unprognostic (2.17e-3)" "unprognostic (1.76e-1)" "potential prognostic favorable (9.63e-7)" "unprognostic (3.17e-3)" "unprognostic (2.39e-2)" "unprognostic (1.39e-3)" "unprognostic (2.60e-1)" "unprognostic (9.94e-2)" "unprognostic (2.63e-1)" "unprognostic (6.87e-2)" "unprognostic (9.69e-3)" "unprognostic (2.28e-1)" "unprognostic (1.18e-1)" "unprognostic (1.21e-1)" "unprognostic (4.94e-2)" "unprognostic (4.60e-1)" "unprognostic (2.99e-1)" "unprognostic (1.31e-1)" CD209 "CDSIGN, CLEC4L, DC-SIGN, DC-SIGN1, hDC-SIGN" ENSG00000090659 "CD209 molecule" Q9NNX6 19 7739993-7747564 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Cell adhesion, Endocytosis, Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 32.0;placenta: 21.4" "Cell type enhanced" "Detected in some" "Kupffer cells: 1.0;Macrophages: 2.7" "Cell type enhanced" "Detected in single" "central nervous system macrophage: 1.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 1.4;intermediate monocyte: 1.4;myeloid DC: 1.2" "Group enriched" "Detected in many" 5 "dendritic cells: 1.2;monocytes: 1.4" "Cancer enhanced" "Detected in single" "thyroid cancer: 1.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Minor Salivary Gland - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid gland - Macrophages" "CAB032436, CAB033831" Supported "Intracellular and membrane" Receptor NA NA 4400000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 6 "CAB032436: , CAB033831: " "unprognostic (2.52e-1)" "unprognostic (1.41e-1)" "unprognostic (2.46e-3)" "unprognostic (1.64e-2)" "unprognostic (5.23e-2)" "unprognostic (2.39e-1)" "unprognostic (3.58e-2)" "unprognostic (1.46e-1)" "unprognostic (1.78e-1)" "unprognostic (1.90e-1)" "unprognostic (1.68e-1)" "unprognostic (3.23e-1)" "unprognostic (3.52e-2)" "unprognostic (3.12e-2)" "unprognostic (2.70e-1)" "unprognostic (9.00e-3)" "unprognostic (1.63e-1)" "unprognostic (2.21e-2)" "unprognostic (2.23e-1)" "unprognostic (2.55e-2)" "unprognostic (1.13e-1)" "unprognostic (3.25e-3)" "unprognostic (7.59e-2)" "unprognostic (1.59e-1)" "unprognostic (2.99e-2)" "unprognostic (1.65e-1)" "unprognostic (3.12e-2)" "unprognostic (1.26e-1)" CD22 "SIGLEC-2, SIGLEC2" ENSG00000012124 "CD22 molecule" P20273 19 35319261-35347361 "CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 215.0;ovary: 124.5" "Cell type enhanced" "Detected in many" "B-cells: 284.8;Epididymal efferent duct absorptive cells: 99.6;Fallopian secretory cells: 47.4;Granulosa cells: 71.4;Mast cells: 129.2;Oligodendrocytes: 239.5;Ovarian stromal cells: 77.5" "Group enriched" "Detected in many" 30 "committed oligodendrocyte precursor: 159.9;oligodendrocyte: 290.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 24 "memory B-cell: 97.9;naive B-cell: 120.7" "Lineage enriched" "Detected in many" 26 "B-cells: 120.7" "Group enriched" "Detected in many" 9 "Leukemia: 48.4;lymphoma: 193.5" "Adipose visceral - T-cells, Colon - Mast cells, Prostate - Fibroblasts, Spleen - B-cells (Spleen)" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB002418, HPA024353, HPA066523" Enhanced NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 11: White matter - Signal transduction" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 9 "CAB002418: , HPA024353: , HPA066523: " "unprognostic (6.63e-2)" "unprognostic (2.17e-2)" "unprognostic (1.28e-1)" "unprognostic (1.65e-2)" "unprognostic (9.99e-2)" "unprognostic (5.34e-2)" "unprognostic (1.27e-1)" "unprognostic (6.33e-2)" "unprognostic (8.98e-3)" "unprognostic (5.14e-2)" "unprognostic (4.21e-2)" "unprognostic (6.39e-2)" "unprognostic (7.23e-2)" "unprognostic (3.04e-1)" "unprognostic (8.42e-2)" "unprognostic (2.48e-3)" "unprognostic (1.40e-1)" "unprognostic (1.50e-1)" "unprognostic (1.79e-1)" "unprognostic (2.38e-1)" "unprognostic (2.32e-1)" "unprognostic (6.57e-2)" "unprognostic (8.29e-3)" "potential prognostic favorable (9.77e-4)" "unprognostic (1.09e-3)" "unprognostic (1.52e-2)" "unprognostic (1.88e-1)" "unprognostic (8.74e-2)" "unprognostic (2.76e-2)" "unprognostic (1.56e-2)" "unprognostic (2.93e-2)" CD226 "DNAM-1, DNAM1, PTA1, TLiSA1" ENSG00000150637 "CD226 molecule" Q15762 18 69831158-69961803 "CD markers, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "lymphoid tissue: 19.0;parathyroid gland: 58.7" "Cell type enriched" "Detected in many" 6 "Platelets: 1418.7" "Cell type enhanced" "Detected in all" "leukocyte: 317.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "gdT-cell: 36.7;MAIT T-cell: 13.4;memory CD4 T-cell: 28.9;memory CD8 T-cell: 22.5;naive CD4 T-cell: 15.8;naive CD8 T-cell: 17.4;NK-cell: 29.7;T-reg: 11.3" "Group enriched" "Detected in many" 11 "NK-cells: 29.7;T-cells: 36.7" "Group enriched" "Detected in some" 6 "Leukemia: 8.2;lymphoma: 10.3" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Colon - T-cells, Lung - T-cells, Minor Salivary Gland - T-cells, Prostate - T-cells, Skeletal muscle - Fibroblasts, Stomach - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA015715, HPA015865" Supported Supported "Nucleoplasm,Plasma membrane,Centriolar satellite" NA No 830000 "Cluster 15: NK-cells - Unknown function" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 47: Platelets - Hemostasis" 2 "Plasma membrane" "Nucleoplasm, Centriolar satellite" "HPA015715: , HPA015865: " "unprognostic (1.93e-3)" "unprognostic (2.18e-1)" "unprognostic (5.26e-2)" "unprognostic (1.02e-1)" "unprognostic (2.67e-1)" "unprognostic (1.15e-1)" "potential prognostic favorable (1.08e-4)" "unprognostic (1.85e-1)" "unprognostic (2.08e-3)" "unprognostic (2.37e-1)" "unprognostic (1.83e-2)" "unprognostic (1.06e-1)" "unprognostic (3.96e-2)" "unprognostic (8.63e-2)" "unprognostic (2.82e-1)" "unprognostic (4.43e-2)" CD24 CD24A ENSG00000272398 "CD24 molecule" P25063 6 106969831-106975627 "Cancer-related genes, CD markers, Disease related genes, Essential proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 1527.8" "Cell type enhanced" "Detected in many" "Breast lactating cells: 3586.9;Esophageal apical cells: 14637.2;Esophageal suprabasal cells: 3732.4;Pancreatic acinar cells: 2829.5;Parietal cells: 1942.9;Salivary duct cells: 1892.2" "Cell type enriched" "Detected in many" 4 "ependymal cell: 145.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 29 "eosinophil: 86.4;memory B-cell: 61.3;naive B-cell: 39.9" "Group enriched" "Detected in many" 240 "B-cells: 61.3;granulocytes: 86.4" "Cancer enhanced" "Detected in all" "breast cancer: 1239.9" "Adrenal gland - Adrenal medulla cells, Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 159.0" "HPA045879, CAB078471" Approved Approved Vesicles "Intracellular and membrane" "No annotated function" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 60: Stomach - Digestion" "Cluster 29: Forebrain - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 85: Squamous epithelial cells - Keratinization" 2 Vesicles "CAB078471: , HPA045879: " "unprognostic (1.35e-1)" "potential prognostic unfavorable (2.01e-7)" "unprognostic (3.01e-1)" "unprognostic (1.79e-3)" "unprognostic (7.39e-2)" "unprognostic (1.88e-3)" "unprognostic (2.76e-2)" "unprognostic (6.97e-2)" "unprognostic (1.65e-1)" "unprognostic (1.94e-2)" "unprognostic (9.58e-2)" "unprognostic (9.50e-2)" "potential prognostic unfavorable (8.15e-5)" "unprognostic (2.69e-2)" "unprognostic (1.89e-1)" "unprognostic (4.25e-2)" "unprognostic (4.44e-1)" "unprognostic (7.10e-2)" "unprognostic (2.64e-1)" "unprognostic (2.25e-2)" "unprognostic (9.01e-2)" "potential prognostic favorable (8.25e-4)" "unprognostic (1.33e-1)" "unprognostic (2.36e-1)" "unprognostic (2.94e-1)" "unprognostic (1.27e-1)" "unprognostic (1.31e-1)" "unprognostic (3.06e-1)" CD244 "2B4, NAIL, NKR2B4, Nmrk, SLAMF4" ENSG00000122223 "CD244 molecule" Q9BZW8 1 160830160-160862887 "CD markers, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 9.4;lymphoid tissue: 15.9" "Cell type enhanced" "Detected in some" "B-cells: 16.4;cDC: 11.2;Hematopoietic stem cells: 34.0;Kupffer cells: 33.8;Mesothelial cells: 15.0;monocytes: 18.5;NK-cells: 76.1;T-cells: 22.8;Thymocytes: 27.1" "Cell type enriched" "Detected in some" 8 "leukocyte: 62.6" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 4 "basophil: 473.6" "Lineage enriched" "Detected in many" 6 "granulocytes: 473.6" "Cancer enriched" "Detected in single" 17 "Leukemia: 15.3" "Adipose subcutaneous - T-cells, Adipose visceral - Mesothelial cells, Adrenal gland - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Lung - NK-cells (Lung), Minor Salivary Gland - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Stomach - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 9 "unprognostic (4.31e-2)" "unprognostic (1.14e-1)" "unprognostic (2.98e-2)" "unprognostic (1.01e-1)" "unprognostic (9.44e-2)" "unprognostic (7.28e-3)" "unprognostic (1.70e-1)" "unprognostic (2.16e-2)" "unprognostic (7.87e-3)" "unprognostic (3.34e-1)" "unprognostic (9.95e-2)" "unprognostic (2.00e-1)" "unprognostic (1.95e-1)" CD247 "CD3-ZETA, CD3H, CD3Q, CD3Z, CD3ZETA, TCRZ" ENSG00000198821 "CD247 molecule" P20963 1 167425027-167518640 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Adaptive immunity, Host-virus interaction, Immunity" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "bone marrow: 38.0;lymphoid tissue: 150.1" "Group enriched" "Detected in many" 7 "NK-cells: 2151.4;T-cells: 626.7" "Cell type enriched" "Detected in many" 41 "leukocyte: 1073.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 20 "gdT-cell: 336.7;MAIT T-cell: 189.2;memory CD4 T-cell: 181.3;memory CD8 T-cell: 205.8;naive CD4 T-cell: 227.8;naive CD8 T-cell: 184.5;NK-cell: 213.0;T-reg: 242.5" "Group enriched" "Detected in all" 25 "NK-cells: 213.0;T-cells: 336.7" "Group enriched" "Detected in some" 11 "Leukemia: 23.4;lymphoma: 21.4;Myeloma: 16.1" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Minor Salivary Gland - T-cells, Pancreas - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Skin - T-cells, Stomach - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB004651, HPA008750" Enhanced NA NA "Cluster 27: T-cells - Unknown function" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 19 "CAB004651: , HPA008750: " "unprognostic (4.54e-2)" "potential prognostic favorable (3.28e-4)" "unprognostic (2.84e-2)" "unprognostic (2.63e-3)" "unprognostic (4.65e-2)" "unprognostic (1.41e-1)" "unprognostic (5.15e-3)" "unprognostic (5.40e-2)" "potential prognostic favorable (4.82e-4)" "unprognostic (1.22e-1)" "unprognostic (2.09e-1)" "unprognostic (9.98e-2)" "unprognostic (2.79e-2)" "unprognostic (9.49e-3)" "unprognostic (4.73e-3)" "unprognostic (6.01e-3)" "unprognostic (9.34e-2)" "unprognostic (1.98e-1)" "unprognostic (1.40e-1)" "unprognostic (4.62e-2)" "unprognostic (1.84e-1)" "unprognostic (2.07e-2)" "unprognostic (1.40e-1)" "unprognostic (1.92e-1)" "unprognostic (1.38e-2)" "unprognostic (1.35e-1)" "unprognostic (2.68e-3)" "unprognostic (3.61e-1)" "unprognostic (2.19e-2)" "unprognostic (1.88e-2)" "unprognostic (2.05e-1)" CD248 "CD164L1, TEM1" ENSG00000174807 "CD248 molecule" Q9HCU0 11 66314494-66317044 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 219.6;breast: 146.3" "Cell type enhanced" "Detected in some" "Decidual stromal cells: 442.9;Endometrial stromal cells: 119.5;Fibroblasts: 145.8;Hepatic stellate cells: 38.7;Leydig cells: 84.5;Pericytes: 56.8" "Group enriched" "Detected in some" 6 "fibroblast: 42.7;pericyte: 51.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "naive CD8 T-cell: 21.9" "Lineage enriched" "Detected in single" 145 "T-cells: 21.9" "Group enriched" "Detected in many" 6 "Bone cancer: 137.0;Neuroblastoma: 39.8;Sarcoma: 67.1" "Adrenal gland - Fibroblasts, Breast - Adipocytes (Breast), Colon - Fibroblasts, Liver - Hepatic stellate cells, Minor Salivary Gland - Fibroblasts, Pituitary gland - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblasts_1, Skin - Fibroblasts_2, Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051856 Enhanced Approved "Plasma membrane" NA NA 12000000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 4 "Plasma membrane" "HPA051856: " "unprognostic (2.03e-2)" "unprognostic (2.07e-1)" "unprognostic (6.90e-2)" "unprognostic (3.33e-2)" "unprognostic (2.04e-2)" "unprognostic (2.42e-1)" "unprognostic (5.25e-2)" "unprognostic (9.31e-3)" "unprognostic (3.84e-1)" "unprognostic (9.96e-2)" "unprognostic (5.53e-2)" "unprognostic (1.69e-3)" "unprognostic (1.08e-3)" "unprognostic (7.18e-3)" "unprognostic (3.33e-1)" "unprognostic (2.46e-2)" "unprognostic (6.04e-2)" "unprognostic (2.16e-2)" "unprognostic (1.86e-1)" "unprognostic (6.67e-2)" "unprognostic (1.77e-1)" "unprognostic (3.86e-2)" "unprognostic (1.74e-1)" "unprognostic (5.25e-2)" "unprognostic (5.28e-2)" "unprognostic (2.49e-1)" "unprognostic (8.49e-2)" "unprognostic (4.82e-2)" "unprognostic (5.92e-2)" "unprognostic (3.99e-2)" "unprognostic (1.59e-1)" CD27 "S152, TNFRSF7, Tp55" ENSG00000139193 "CD27 molecule" P26842 12 6444955-6451718 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" Apoptosis Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 36.5;lymphoid tissue: 138.4" "Cell type enriched" "Detected in some" 5 "Plasma cells: 471.6" "Cell type enriched" "Detected in some" 19 "leukocyte: 37.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "T-reg: 642.1" "Group enriched" "Detected in all" 7 "B-cells: 294.3;T-cells: 642.1" "Cancer enriched" "Detected in some" 7 "lymphoma: 88.8" "Adipose subcutaneous - T-cells, Breast - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Prostate - T-cells, Spleen - B-cells (Spleen), Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB002420, HPA038936, HPA069501, CAB080304" Enhanced Approved Vesicles NA NA 190000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 11: White matter - Signal transduction" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 78: Plasma cells - Antibody production & ER-stress response" 42 Vesicles "CAB002420: , CAB080304: , HPA038936: , HPA069501: " "unprognostic (1.29e-2)" "unprognostic (4.14e-3)" "unprognostic (4.96e-3)" "unprognostic (2.73e-3)" "unprognostic (9.54e-2)" "unprognostic (2.25e-1)" "unprognostic (1.19e-2)" "potential prognostic favorable (4.01e-6)" "unprognostic (1.26e-1)" "unprognostic (1.61e-1)" "unprognostic (2.19e-3)" "unprognostic (4.65e-2)" "unprognostic (1.83e-1)" "unprognostic (2.66e-2)" "unprognostic (7.30e-2)" "unprognostic (1.51e-1)" "unprognostic (3.14e-1)" "unprognostic (1.99e-2)" "unprognostic (7.52e-3)" "unprognostic (7.49e-2)" "unprognostic (4.54e-2)" "unprognostic (1.80e-1)" "potential prognostic favorable (7.76e-4)" "unprognostic (6.41e-2)" "potential prognostic favorable (7.12e-5)" "unprognostic (4.50e-1)" "unprognostic (4.84e-2)" "unprognostic (9.72e-2)" "unprognostic (3.19e-1)" CD274 "B7-H, B7-H1, B7H1, PD-L1, PDCD1LG1, PDL1" ENSG00000120217 "CD274 molecule" Q9NZQ7 9 5450503-5470566 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Adaptive immunity, Immunity" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 16.1" "Cell type enhanced" "Detected in many" "cDC: 33.1;Epididymal basal cells: 27.1;Extravillous trophoblasts: 48.3;Mast cells: 61.3;Megakaryocyte progenitors: 55.8;Microglia: 30.2;Neutrophils: 34.0;Syncytiotrophoblasts: 72.9" "Cell type enriched" "Detected in many" 5 "central nervous system macrophage: 36.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 6.7" "Lineage enriched" "Detected in many" 5 "granulocytes: 6.7" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA003528, CAB076385, CAB080537" Enhanced Supported "Nucleoplasm,Nuclear speckles,Plasma membrane" "Secreted - unknown location" Receptor NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 82: Dendritic cells - Antigen presentation" 60 "Nucleoplasm, Nuclear speckles, Plasma membrane" "CAB076385: , CAB080537: , HPA003528: " "unprognostic (1.57e-1)" "unprognostic (6.40e-2)" "unprognostic (9.65e-3)" "unprognostic (1.01e-1)" "unprognostic (1.98e-2)" "unprognostic (4.77e-2)" "unprognostic (9.07e-2)" "unprognostic (8.18e-2)" "unprognostic (4.37e-2)" "unprognostic (1.06e-1)" "potential prognostic favorable (5.33e-4)" "unprognostic (9.06e-2)" "unprognostic (1.18e-1)" "unprognostic (3.02e-3)" "unprognostic (1.32e-1)" "unprognostic (3.70e-3)" "unprognostic (3.49e-1)" "unprognostic (1.55e-1)" "unprognostic (4.51e-3)" "unprognostic (3.35e-3)" "unprognostic (9.49e-3)" "unprognostic (3.27e-3)" "unprognostic (3.46e-2)" "unprognostic (3.48e-2)" "unprognostic (5.88e-2)" "unprognostic (6.88e-2)" "unprognostic (2.16e-2)" "unprognostic (2.49e-1)" CD276 "B7-H3, B7H3, B7RP-2" ENSG00000103855 "CD276 molecule" Q5ZPR3 15 73683966-73714514 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 320.9;Hofbauer cells: 132.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Skin - Fibroblasts_2, Spleen - Fibroblasts_1, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009285, HPA017139, CAB017826" Enhanced Approved Vesicles NA NA 3700000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 23: Choroid plexus - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 2 Vesicles "CAB017826: , HPA009285: , HPA017139: " "unprognostic (7.52e-3)" "unprognostic (1.75e-1)" "unprognostic (1.14e-1)" "unprognostic (1.68e-1)" "unprognostic (1.60e-1)" "unprognostic (7.74e-3)" "unprognostic (8.31e-2)" "unprognostic (1.10e-1)" "unprognostic (4.15e-2)" "unprognostic (5.03e-2)" "unprognostic (4.14e-3)" "unprognostic (1.25e-1)" "unprognostic (3.64e-2)" "unprognostic (1.68e-2)" "potential prognostic unfavorable (2.76e-4)" "unprognostic (7.89e-3)" "potential prognostic unfavorable (4.79e-4)" "unprognostic (7.82e-3)" "unprognostic (8.01e-2)" "unprognostic (2.03e-2)" "unprognostic (9.72e-2)" "unprognostic (1.15e-2)" "potential prognostic unfavorable (2.02e-4)" "unprognostic (3.07e-1)" "unprognostic (2.02e-1)" "unprognostic (4.24e-2)" "unprognostic (1.42e-1)" "unprognostic (2.52e-1)" "unprognostic (3.25e-1)" "unprognostic (4.25e-2)" "unprognostic (1.39e-1)" CD28 ENSG00000178562 "CD28 molecule" P10747 2 203706475-203738912 "CD markers, Predicted membrane proteins" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "lymphoid tissue: 28.7;placenta: 13.9" "Group enriched" "Detected in some" 6 "Hofbauer cells: 112.8;T-cells: 147.1;Thymocytes: 50.8" "Cell type enriched" "Detected in some" 19 "leukocyte: 55.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "T-reg: 102.2" "Lineage enriched" "Detected in many" 7 "T-cells: 102.2" "Cancer enriched" "Detected in some" 13 "Myeloma: 98.6" "Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Thyroid gland - T-cells" "Region enhanced" "Detected in single" "olfactory bulb: 1.0" "Low region specificity" "Detected in all" "HPA041233, HPA070003" Enhanced Supported "Plasma membrane" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 20: Myeloma - Immune response" "Cluster 9: T-cells - Adaptive immunity: Regulation" 5 "Plasma membrane" "HPA041233: , HPA070003: " "unprognostic (2.55e-1)" "unprognostic (1.55e-1)" "unprognostic (6.70e-2)" "unprognostic (3.29e-1)" "unprognostic (4.51e-2)" "potential prognostic favorable (6.76e-4)" "unprognostic (2.28e-1)" "unprognostic (2.26e-1)" "unprognostic (5.95e-2)" "unprognostic (9.28e-3)" "unprognostic (5.33e-3)" "unprognostic (1.67e-1)" "unprognostic (7.67e-2)" "unprognostic (1.38e-1)" "unprognostic (1.10e-1)" "unprognostic (4.10e-3)" "unprognostic (4.00e-2)" "unprognostic (9.82e-2)" "unprognostic (1.11e-1)" "unprognostic (1.46e-2)" CD2AP CMS ENSG00000198087 "CD2 associated protein" Q9Y5K6 6 47477789-47627263 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Host-virus interaction, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Enterocytes: 647.5;pDCs: 811.4" "Cell type enhanced" "Detected in all" "endothelial cell: 336.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 9.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003267, HPA003326, CAB004352" Enhanced Supported "Plasma membrane,Centriolar satellite" NA NA 21000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 51: Secretory epithelial cells - Mixed function" 62 "Plasma membrane" "Centriolar satellite" "CAB004352: , HPA003267: , HPA003326: " "potential prognostic favorable (9.26e-6)" "unprognostic (7.09e-3)" "unprognostic (2.46e-1)" "unprognostic (2.58e-2)" "unprognostic (1.39e-1)" "unprognostic (1.53e-2)" "unprognostic (2.61e-1)" "unprognostic (1.21e-1)" "unprognostic (8.05e-2)" "unprognostic (4.11e-2)" "potential prognostic favorable (5.79e-7)" "unprognostic (1.57e-2)" "unprognostic (1.91e-2)" "unprognostic (1.91e-3)" "unprognostic (2.08e-2)" "potential prognostic unfavorable (7.96e-4)" "unprognostic (6.08e-2)" "unprognostic (3.37e-1)" "unprognostic (4.69e-2)" "unprognostic (2.86e-1)" "unprognostic (1.43e-1)" "potential prognostic unfavorable (2.28e-4)" "unprognostic (1.06e-2)" "unprognostic (1.90e-1)" "unprognostic (1.72e-2)" "unprognostic (2.08e-2)" "unprognostic (2.99e-2)" "unprognostic (4.33e-2)" "unprognostic (3.24e-1)" "unprognostic (7.58e-2)" "unprognostic (2.16e-1)" CD2BP2 "LIN1, PPP1R59, Snu40, U5-52K" ENSG00000169217 "CD2 cytoplasmic tail binding protein 2" O95400 16 30350773-30355308 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 124.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041508, HPA061309" Enhanced Enhanced "Nuclear speckles,Cytosol" Yes No "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 64: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 159 "Nuclear speckles" Cytosol "HPA041508: , HPA061309: " "unprognostic (1.36e-1)" "unprognostic (4.16e-2)" "unprognostic (1.51e-1)" "unprognostic (7.75e-2)" "unprognostic (1.16e-1)" "unprognostic (1.59e-1)" "unprognostic (5.69e-2)" "potential prognostic favorable (3.07e-5)" "unprognostic (1.05e-1)" "unprognostic (4.57e-2)" "potential prognostic favorable (1.32e-6)" "unprognostic (9.43e-2)" "unprognostic (5.06e-3)" "potential prognostic unfavorable (3.22e-5)" "unprognostic (3.81e-3)" "unprognostic (1.57e-1)" "unprognostic (2.60e-2)" "unprognostic (1.19e-1)" "unprognostic (9.83e-2)" "unprognostic (9.48e-2)" "unprognostic (1.41e-1)" "unprognostic (4.89e-2)" "unprognostic (7.32e-2)" "unprognostic (2.04e-1)" "unprognostic (5.32e-2)" "unprognostic (5.33e-2)" "unprognostic (6.89e-2)" "unprognostic (1.40e-1)" "unprognostic (8.96e-2)" "unprognostic (3.40e-1)" "unprognostic (4.62e-3)" CD300A "CMRF-35-H9, CMRF35H, IGSF12, IRC1, IRC2, Irp60" ENSG00000167851 "CD300a molecule" Q9UGN4 17 74466399-74484794 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 94.5" "Cell type enhanced" "Detected in some" "cDC: 60.8;Hofbauer cells: 149.0;Kupffer cells: 113.8;Macrophages: 93.2;Mast cells: 48.8;Microglia: 53.2;monocytes: 84.7;Neutrophils: 125.4;NK-cells: 100.4;pDCs: 89.7;Thymocytes: 33.9" "Group enriched" "Detected in some" 42 "central nervous system macrophage: 63.4;leukocyte: 75.1" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 59.6" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Leukemia: 40.9;Myeloma: 12.0" "Adipose subcutaneous - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Liver - Kupffer cells, Pituitary gland - Macrophages, Spleen - Macrophages, Stomach - Macrophages, Thyroid gland - T-cells" "HPA010971, HPA011645" Approved Approved "Vesicles,Plasma membrane,Cytosol" "Intracellular and membrane" Receptor NA NA 320000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 59: Leukemia - T-cell receptor" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 6 "Plasma membrane" "Vesicles, Cytosol" "HPA010971: , HPA011645: " "unprognostic (1.86e-1)" "unprognostic (2.92e-1)" "unprognostic (3.38e-1)" "unprognostic (9.06e-2)" "unprognostic (4.15e-2)" "unprognostic (2.14e-1)" "unprognostic (8.23e-2)" "unprognostic (5.51e-2)" "unprognostic (1.62e-1)" "unprognostic (1.87e-1)" "unprognostic (4.54e-2)" "unprognostic (4.71e-1)" "unprognostic (1.41e-1)" "unprognostic (1.15e-2)" "unprognostic (3.63e-2)" "unprognostic (2.50e-2)" "potential prognostic unfavorable (7.08e-4)" "unprognostic (1.21e-1)" "unprognostic (1.86e-2)" "unprognostic (1.95e-3)" "unprognostic (1.86e-1)" "unprognostic (2.34e-2)" "unprognostic (5.97e-3)" "unprognostic (9.09e-2)" "unprognostic (8.92e-2)" "unprognostic (3.60e-2)" "unprognostic (6.56e-2)" "unprognostic (4.72e-2)" "unprognostic (3.76e-3)" "unprognostic (1.15e-1)" "unprognostic (2.20e-1)" CD300C "CMRF-35A, CMRF35, CMRF35A, IGSF16, LIR" ENSG00000167850 "CD300c molecule" Q08708 17 74541073-74546115 "CD markers, Predicted membrane proteins" Immunity Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 9.2;lung: 7.9;lymphoid tissue: 6.9" "Cell type enhanced" "Detected in some" "cDC: 14.2;Hofbauer cells: 36.8;Kupffer cells: 30.7;Macrophages: 17.2;Mast cells: 7.3;Monocyte progenitors: 11.3;monocytes: 31.8" "Group enriched" "Detected in some" 8 "central nervous system macrophage: 4.9;leukocyte: 3.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 228.5;non-classical monocyte: 243.7" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Leukemia: 5.2;lymphoma: 5.0;thyroid cancer: 1.5" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Lung - Macrophages, Minor Salivary Gland - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Spleen - Macrophages, Stomach - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA014523, HPA060349" Approved Uncertain "Golgi apparatus,Vesicles,Mitochondria" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 10 "Golgi apparatus" "Vesicles, Mitochondria" "HPA014523: , HPA060349: " "unprognostic (2.04e-1)" "unprognostic (5.85e-2)" "unprognostic (3.60e-2)" "unprognostic (1.10e-1)" "unprognostic (3.72e-1)" "unprognostic (1.45e-1)" "unprognostic (1.22e-1)" "unprognostic (3.51e-1)" "unprognostic (3.42e-2)" "unprognostic (3.49e-3)" "unprognostic (2.16e-1)" "unprognostic (1.19e-1)" "unprognostic (6.48e-2)" "unprognostic (9.39e-2)" "unprognostic (6.85e-2)" "unprognostic (1.30e-1)" "unprognostic (9.67e-2)" "unprognostic (1.66e-2)" "unprognostic (3.79e-1)" "unprognostic (9.02e-2)" "unprognostic (1.73e-1)" "unprognostic (5.91e-2)" "unprognostic (7.46e-3)" "unprognostic (7.99e-3)" "unprognostic (7.86e-2)" "unprognostic (4.96e-3)" "potential prognostic unfavorable (2.96e-4)" CD300E "CD300LE, CLM2, IREM2" ENSG00000186407 "CD300e molecule" Q496F6 17 74609885-74623738 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" Immunity Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 45.3;lymphoid tissue: 35.3" "Cell type enriched" "Detected in some" 9 "monocytes: 332.3" "Cell type enriched" "Detected in some" 13 "leukocyte: 20.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 87.9;intermediate monocyte: 135.0;non-classical monocyte: 149.1" "Lineage enriched" "Detected in many" 7 "monocytes: 149.1" "Not detected" "Not detected" "Colon - Neutrophils, Kidney - Macrophages, Thyroid gland - Neutrophils" "Not detected" "Not detected" HPA015570 Uncertain NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 5 "HPA015570: " "unprognostic (1.22e-1)" "unprognostic (1.27e-1)" "unprognostic (2.89e-2)" "unprognostic (8.03e-2)" "unprognostic (1.94e-1)" "unprognostic (1.97e-1)" "unprognostic (3.78e-3)" "unprognostic (1.13e-1)" "unprognostic (1.09e-2)" "unprognostic (7.86e-2)" "unprognostic (1.05e-1)" "unprognostic (2.07e-2)" "potential prognostic unfavorable (5.43e-4)" "unprognostic (1.14e-2)" "unprognostic (7.27e-2)" "unprognostic (2.57e-2)" "unprognostic (1.78e-3)" "unprognostic (1.39e-1)" "unprognostic (8.57e-2)" "unprognostic (2.00e-2)" "potential prognostic unfavorable (3.54e-4)" "potential prognostic unfavorable (9.81e-4)" CD300H ENSG00000284690 "CD300H molecule (gene/pseudogene)" A0A0K2S4Q6 17 74560701-74567343 "Essential proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 3.4;lymphoid tissue: 7.3" "Group enriched" "Detected in some" 29 "cDC: 3.7;Macrophages: 1.2;monocytes: 4.5;Neutrophils: 2.3" "Cell type enriched" "Detected in single" 27 "leukocyte: 2.8" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 9 "intermediate monocyte: 655.3;non-classical monocyte: 1135.8" "Lineage enriched" "Detected in all" 12 "monocytes: 1135.8" "Cancer enriched" "Detected in single" 7 "lymphoma: 2.1" "Kidney - Macrophages" "Low region specificity" "Detected in all" "Secreted to blood" "No annotated function" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" CD300LB "CLM7, TREM5" ENSG00000178789 "CD300 molecule like family member b" A8K4G0 17 74521174-74531475 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" Immunity Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 7.3;lymphoid tissue: 7.7" "Group enriched" "Detected in some" 4 "cDC: 49.5;Macrophages: 29.9;monocytes: 54.3;Neutrophils: 14.6" "Cell type enriched" "Detected in some" 4 "leukocyte: 6.1" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in some" 5 "cerebral cortex: 34.0" "Immune cell enhanced" "Detected in many" "eosinophil: 76.1" "Group enriched" "Detected in many" 53 "dendritic cells: 25.1;granulocytes: 76.1;monocytes: 31.7" "Cancer enriched" "Detected in single" 5 "Leukemia: 1.8" "Lung - NK-cells (Lung), Thyroid gland - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA060449 Approved "Plasma membrane" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 5 "Plasma membrane" "HPA060449: " "unprognostic (4.72e-2)" "unprognostic (6.30e-2)" "unprognostic (9.70e-2)" "unprognostic (1.46e-1)" "unprognostic (3.56e-2)" "unprognostic (2.32e-2)" "unprognostic (1.04e-2)" "unprognostic (1.66e-1)" "unprognostic (9.63e-2)" "unprognostic (1.98e-3)" CD300LD "CD300D, CMRF35A4" ENSG00000204345 "CD300 molecule like family member d" Q6UXZ3 17 74579365-74592283 "CD markers, Predicted membrane proteins" Immunity Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Breast lactating cells: 2.6;Epicardial cells: 2.3;monocytes: 3.6;Neutrophils: 2.1;Salivary acinar cells: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "neutrophil: 5.1" "Lineage enriched" "Detected in single" 6 "granulocytes: 5.1" "Not detected" "Not detected" "Testis - Late spermatids" HPA027756 Uncertain NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 48: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 2 "HPA027756: " "unprognostic (1.18e-1)" "unprognostic (1.76e-1)" CD300LF "CD300f, CLM1, IGSF13, IREM1, NKIR" ENSG00000186074 "CD300 molecule like family member f" Q8TDQ1 17 74694311-74712978 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" Immunity Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 25.5;lung: 16.6;lymphoid tissue: 28.5" "Cell type enhanced" "Detected in some" "Innate lymphoid cells: 22.9;Kupffer cells: 29.7;Macrophages: 29.0;Microglia: 20.1;Monocyte progenitors: 42.7;monocytes: 49.3;Neutrophil progenitors: 35.5;Neutrophils: 94.6;Tuft cells: 172.9" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 24.1;lower rhombic lip: 20.3;upper rhombic lip: 24.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 234.8" "Group enriched" "Detected in many" 43 "dendritic cells: 63.8;granulocytes: 234.8;monocytes: 193.8" "Cancer enriched" "Detected in single" 78 "Leukemia: 19.2" "Adrenal gland - Macrophages, Lung - Macrophages" HPA013712 Supported NA NA 38000 "Cluster 25: Non-specific - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 25: Non-specific - Transcription" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 1 "HPA013712: " "unprognostic (1.03e-1)" "unprognostic (1.61e-1)" "unprognostic (1.57e-1)" "unprognostic (9.42e-3)" "unprognostic (1.96e-1)" "unprognostic (2.12e-1)" "unprognostic (3.52e-2)" "unprognostic (1.40e-1)" "unprognostic (9.36e-2)" "unprognostic (3.45e-1)" "unprognostic (4.19e-2)" "unprognostic (1.14e-1)" "unprognostic (1.66e-3)" "unprognostic (1.92e-1)" "unprognostic (8.41e-2)" "potential prognostic favorable (7.85e-4)" "unprognostic (6.87e-2)" "unprognostic (2.00e-1)" "unprognostic (2.92e-1)" "unprognostic (3.21e-1)" "unprognostic (2.05e-1)" "unprognostic (3.67e-2)" "unprognostic (4.38e-2)" "unprognostic (2.27e-1)" "unprognostic (6.23e-2)" "unprognostic (2.17e-2)" "unprognostic (1.61e-2)" "unprognostic (7.28e-2)" "unprognostic (3.98e-2)" "unprognostic (6.69e-2)" "unprognostic (1.62e-1)" CD300LG "CLM9, Trem4" ENSG00000161649 "CD300 molecule like family member g" Q6UXG3 17 43847148-43863639 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" Immunity Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 123.7;breast: 107.6;placenta: 55.4" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 21.6;Epididymal principal cells: 8.8;Leydig cells: 12.8;Pericytes: 7.0;Peritubular myoid cells: 29.2;Sertoli cells: 17.8;Vascular endothelial cells: 68.1" "Cell type enhanced" "Detected in single" "endothelial cell: 1.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Sertoli cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA004131 Approved Calyx NA NA 1700000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 19: Astrocytes - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 6 Calyx "HPA004131: " "unprognostic (8.68e-3)" "unprognostic (5.65e-2)" "unprognostic (1.83e-2)" "potential prognostic favorable (4.39e-7)" "unprognostic (1.76e-1)" "unprognostic (1.62e-1)" CD302 "BIMLEC, CLEC13A, DCL-1, KIAA0022" ENSG00000241399 "CD302 molecule" Q8IX05 2 159768628-159798255 "CD markers, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 181.2" "Cell type enhanced" "Detected in many" "cDC: 108.1;Hepatocytes: 242.7;Kupffer cells: 431.5;Macrophages: 144.6;Microglia: 118.4;Monocyte progenitors: 187.0;monocytes: 223.9;Neutrophil progenitors: 105.0;Neutrophils: 150.7" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 154.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 215 "dendritic cells: 24.5;granulocytes: 32.3;monocytes: 33.0" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatocytes, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 95000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 21: Non-specific - Metabolism" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 9 "unprognostic (6.14e-2)" "unprognostic (1.75e-2)" "unprognostic (9.19e-2)" "unprognostic (5.94e-2)" "unprognostic (1.16e-1)" "unprognostic (1.94e-1)" "unprognostic (1.17e-1)" "potential prognostic unfavorable (5.12e-4)" "unprognostic (2.10e-2)" "unprognostic (2.83e-2)" "potential prognostic favorable (2.78e-5)" "unprognostic (1.43e-2)" "unprognostic (1.30e-2)" "unprognostic (5.39e-3)" "potential prognostic favorable (9.76e-4)" "potential prognostic favorable (3.69e-4)" "unprognostic (1.93e-1)" "unprognostic (1.50e-2)" "unprognostic (4.43e-2)" "unprognostic (1.33e-2)" "unprognostic (8.30e-2)" "unprognostic (5.24e-2)" "unprognostic (5.33e-2)" "unprognostic (2.33e-1)" "unprognostic (2.19e-1)" "unprognostic (1.59e-1)" "unprognostic (1.96e-1)" "unprognostic (3.53e-3)" "unprognostic (2.09e-1)" "unprognostic (2.27e-2)" "unprognostic (5.26e-2)" CD320 "8D6, 8D6A, TCblR" ENSG00000167775 "CD320 molecule" Q9NPF0 19 8302127-8308358 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" "Growth factor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 582.4;Late primary spermatocytes: 194.9;Vascular endothelial cells: 188.3" "Cell type enriched" "Detected in all" 11 "endothelial cell: 323.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014500, HPA014522" Approved Uncertain Vesicles NA NA 95000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 5: Spleen - Immune response" "Cluster 45: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 2 Vesicles "HPA014500: , HPA014522: " "unprognostic (1.39e-1)" "unprognostic (4.77e-2)" "unprognostic (1.33e-1)" "unprognostic (5.48e-3)" "unprognostic (2.73e-1)" "unprognostic (7.93e-2)" "unprognostic (3.22e-1)" "unprognostic (3.31e-1)" "unprognostic (3.72e-2)" "unprognostic (5.37e-3)" "unprognostic (3.36e-3)" "unprognostic (3.13e-3)" "unprognostic (1.93e-1)" "validated prognostic unfavorable (1.47e-4)" "validated prognostic unfavorable (2.73e-5)" "unprognostic (3.33e-1)" "unprognostic (9.66e-2)" "unprognostic (4.87e-2)" "unprognostic (7.12e-2)" "unprognostic (4.41e-3)" "unprognostic (2.02e-2)" "unprognostic (2.74e-2)" "unprognostic (2.52e-1)" "unprognostic (1.71e-1)" "unprognostic (1.51e-1)" "unprognostic (7.72e-2)" "unprognostic (2.84e-1)" "unprognostic (4.66e-2)" "unprognostic (2.62e-1)" "unprognostic (2.52e-1)" "unprognostic (1.67e-1)" CD33 "FLJ00391, p67, SIGLEC-3, SIGLEC3" ENSG00000105383 "CD33 molecule" P20138 19 51225064-51243860 "CD markers, FDA approved drug targets, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 30.6;lymphoid tissue: 22.6" "Cell type enhanced" "Detected in some" "cDC: 68.5;Hofbauer cells: 120.5;Kupffer cells: 195.8;Macrophages: 53.1;Mast cells: 46.8;Microglia: 25.2;Monocyte progenitors: 54.4;monocytes: 78.6" "Cell type enriched" "Detected in some" 7 "central nervous system macrophage: 37.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 166.7;intermediate monocyte: 122.1;myeloid DC: 213.7;non-classical monocyte: 58.0" "Group enriched" "Detected in many" 9 "dendritic cells: 213.7;monocytes: 166.7" "Cancer enriched" "Detected in many" 8 "Leukemia: 53.6" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Spleen - Macrophages, Stomach - Macrophages, Thyroid gland - Macrophages" "CAB011442, HPA035832, CAB079996, CAB080305" Enhanced Supported "Plasma membrane,Cytosol" NA NA 730000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 24 "Plasma membrane" Cytosol "CAB011442: , CAB079996: , CAB080305: , HPA035832: " "unprognostic (1.63e-1)" "unprognostic (1.82e-2)" "unprognostic (5.32e-2)" "unprognostic (2.66e-1)" "unprognostic (5.81e-2)" "unprognostic (1.90e-1)" "unprognostic (1.16e-1)" "unprognostic (1.50e-2)" "unprognostic (1.57e-1)" "unprognostic (1.52e-1)" "unprognostic (5.05e-3)" "unprognostic (3.40e-1)" "unprognostic (1.40e-1)" "unprognostic (8.17e-2)" "unprognostic (7.35e-3)" "unprognostic (1.02e-2)" "unprognostic (9.04e-3)" "unprognostic (8.70e-2)" "unprognostic (1.20e-1)" "unprognostic (2.96e-2)" "unprognostic (1.18e-1)" "unprognostic (1.58e-1)" "unprognostic (3.68e-2)" "unprognostic (6.54e-2)" "unprognostic (2.02e-2)" "unprognostic (5.50e-2)" "unprognostic (4.78e-2)" "unprognostic (2.20e-1)" "unprognostic (1.19e-3)" "unprognostic (6.67e-2)" "unprognostic (1.37e-1)" CD34 ENSG00000174059 "CD34 molecule" P28906 1 207880972-207911402 "CD markers, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibro-adipogenic progenitors: 167.6;Fibroblasts: 133.0;Hematopoietic stem cells: 99.0;Leydig cells: 165.4;Lymphatic endothelial cells: 40.9;Mesothelial cells: 114.0;Peritubular myoid cells: 136.7;Vascular endothelial cells: 311.4" "Cell type enriched" "Detected in some" 14 "endothelial cell: 241.9" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 124.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "Leukemia: 63.7;Rhabdoid: 115.9;Sarcoma: 87.6" "Pancreas - Endothelial cells, Prostate - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000018, HPA036722, HPA036723" Enhanced Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA 1300000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 2 "Plasma membrane, Cell Junctions" Nucleoplasm "CAB000018: , HPA036722: , HPA036723: " "unprognostic (2.23e-1)" "unprognostic (8.14e-2)" "unprognostic (5.82e-2)" "unprognostic (1.86e-1)" "unprognostic (3.89e-2)" "unprognostic (2.91e-1)" "unprognostic (1.19e-1)" "unprognostic (1.37e-2)" "unprognostic (1.10e-3)" "unprognostic (2.42e-1)" "validated prognostic favorable (1.17e-7)" "validated prognostic favorable (3.94e-4)" "potential prognostic unfavorable (1.29e-4)" "unprognostic (9.78e-3)" "unprognostic (3.33e-3)" "unprognostic (7.61e-2)" "unprognostic (3.53e-1)" "unprognostic (8.50e-2)" "unprognostic (2.28e-1)" "unprognostic (2.88e-1)" "unprognostic (3.65e-2)" "unprognostic (2.59e-2)" "unprognostic (1.94e-1)" "unprognostic (2.57e-2)" "unprognostic (2.95e-2)" "unprognostic (2.30e-1)" "unprognostic (3.13e-2)" "unprognostic (1.44e-2)" "unprognostic (2.28e-1)" "unprognostic (8.34e-2)" "unprognostic (6.05e-2)" CD36 "FAT, GP3B, GP4, GPIV, SCARB3" ENSG00000135218 "CD36 molecule" P16671 7 80369575-80679277 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Lipid transport, Transport" Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 1439.4;breast: 534.4" "Cell type enhanced" "Detected in many" "Adipocytes: 2202.8;Breast lactating cells: 2901.1;Cardiomyocytes: 1067.0;Erythrocyte progenitors: 1495.3;Hofbauer cells: 3461.3;Lymphatic endothelial cells: 1005.7;Myonuclei: 2064.8;Pericytes: 773.1;Platelets: 531.9;Vascular endothelial cells: 611.6" "Group enriched" "Detected in all" 8 "deep-layer near-projecting: 201.4;ependymal cell: 542.2" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 87.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 965.2;intermediate monocyte: 271.3;myeloid DC: 507.9" "Group enriched" "Detected in all" 46 "dendritic cells: 507.9;monocytes: 965.2" "Cancer enhanced" "Detected in many" "thyroid cancer: 57.4" "Adipose visceral - Endothelial cells, Colon - Endothelial cells, Heart muscle - Cardiomyocytes, Liver - Sinusoid Endothelial cells" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 13.2" "HPA002018, CAB025866, HPA071026" Enhanced Enhanced "Golgi apparatus" NA NA 7200000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 46: Brainstem - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 4 "Golgi apparatus" "CAB025866: , HPA002018: , HPA071026: " "unprognostic (4.57e-2)" "unprognostic (2.13e-2)" "potential prognostic favorable (7.86e-4)" "unprognostic (7.58e-3)" "unprognostic (2.12e-1)" "unprognostic (1.72e-2)" "unprognostic (2.26e-1)" "unprognostic (1.74e-1)" "unprognostic (1.71e-1)" "unprognostic (1.27e-1)" "potential prognostic favorable (3.23e-5)" "unprognostic (8.57e-3)" "unprognostic (2.91e-3)" "unprognostic (2.92e-1)" "unprognostic (2.07e-1)" "unprognostic (1.18e-2)" "unprognostic (1.92e-1)" "unprognostic (1.05e-2)" "unprognostic (3.66e-2)" "unprognostic (2.65e-1)" "unprognostic (2.77e-3)" "potential prognostic favorable (6.58e-4)" "unprognostic (4.28e-3)" "unprognostic (9.80e-2)" "unprognostic (2.19e-1)" "unprognostic (8.32e-2)" "unprognostic (6.56e-3)" "potential prognostic unfavorable (8.64e-4)" "unprognostic (8.82e-2)" "unprognostic (4.51e-2)" "unprognostic (2.15e-1)" CD37 TSPAN26 ENSG00000104894 "CD37 molecule" P11049 19 49335171-49343335 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 146.8;intestine: 112.2;lymphoid tissue: 233.1" "Cell type enhanced" "Detected in many" "B-cells: 991.1;cDC: 299.3;Hematopoietic stem cells: 199.9;Hofbauer cells: 451.9;Innate lymphoid cells: 186.7;Late spermatids: 351.2;Macrophages: 174.2;Mast cells: 396.0;monocytes: 301.1;Neutrophils: 356.7;NK-cells: 184.1;pDCs: 358.0;T-cells: 247.8" "Group enriched" "Detected in some" 34 "central nervous system macrophage: 120.8;leukocyte: 131.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Leukemia: 77.0;lymphoma: 248.0" "Adrenal gland - Macrophages, Breast - T-cells, Prostate - T-cells, Skeletal muscle - Macrophages, Spleen - B-cells (Spleen), Testis - Late spermatids, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB002492, HPA032120, HPA032121" Enhanced Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 8 "Golgi apparatus" "Plasma membrane" "CAB002492: , HPA032120: , HPA032121: " "unprognostic (1.12e-1)" "unprognostic (9.68e-3)" "unprognostic (1.49e-2)" "unprognostic (3.07e-2)" "unprognostic (3.44e-2)" "unprognostic (1.78e-1)" "unprognostic (1.59e-2)" "unprognostic (4.12e-1)" "unprognostic (1.89e-2)" "unprognostic (3.70e-1)" "unprognostic (2.72e-1)" "unprognostic (2.88e-1)" "unprognostic (1.13e-1)" "unprognostic (8.87e-2)" "unprognostic (2.39e-2)" "unprognostic (5.78e-3)" "unprognostic (1.00e-1)" "unprognostic (4.04e-2)" "unprognostic (1.51e-1)" "unprognostic (1.26e-1)" "unprognostic (2.27e-1)" "unprognostic (6.54e-2)" "unprognostic (8.70e-2)" "unprognostic (1.54e-1)" "unprognostic (7.16e-2)" "unprognostic (7.67e-2)" "unprognostic (2.45e-3)" "unprognostic (9.56e-2)" "unprognostic (9.96e-3)" "unprognostic (2.33e-2)" "unprognostic (4.47e-2)" CD38 cADPR1 ENSG00000004468 "CD38 molecule" P28907 4 15778275-15853232 "Cancer-related genes, CD markers, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Receptor, Transferase" "Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 58.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 162.3;Astrocytes: 200.6;Hematopoietic stem cells: 196.5;Kupffer cells: 137.3;Megakaryocyte progenitors: 177.9;Megakaryocyte-Erythroid progenitors: 278.9;Monocyte progenitors: 135.3;Myonuclei: 93.6;NK-cells: 154.0;Plasma cells: 469.1;Respiratory ciliated cells: 168.1;Respiratory deuterosomal cells: 95.4;Thymocytes: 143.1" "Group enriched" "Detected in many" 4 "astrocyte: 240.4;leukocyte: 63.7;pericyte: 120.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 18.3" "Group enriched" "Detected in all" 5 "B-cells: 9.9;dendritic cells: 5.8;NK-cells: 18.3" "Group enriched" "Detected in some" 15 "Leukemia: 25.9;lymphoma: 43.3;Myeloma: 35.3" "Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Stomach - Plasma cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002493, HPA022132, CAB025255, HPA052381" Enhanced Supported "Plasma membrane" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 46: Brainstem - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 44: Plasma cells - Antibody production & secretion" 3 "Plasma membrane" "CAB002493: , CAB025255: , HPA022132: , HPA052381: " "unprognostic (1.95e-1)" "unprognostic (1.10e-2)" "unprognostic (2.37e-1)" "unprognostic (1.11e-2)" "unprognostic (2.57e-2)" "unprognostic (1.85e-1)" "unprognostic (1.00e-1)" "unprognostic (2.40e-2)" "potential prognostic favorable (1.51e-4)" "unprognostic (1.18e-3)" "unprognostic (1.31e-1)" "unprognostic (6.14e-3)" "unprognostic (1.00e-1)" "unprognostic (8.73e-2)" "unprognostic (4.05e-2)" "unprognostic (5.33e-3)" "unprognostic (4.45e-1)" "unprognostic (2.37e-1)" "potential prognostic favorable (3.86e-5)" "unprognostic (1.97e-2)" "unprognostic (3.98e-1)" "unprognostic (3.16e-2)" "unprognostic (3.03e-1)" "unprognostic (6.26e-3)" "unprognostic (2.70e-2)" "unprognostic (2.34e-1)" "unprognostic (1.37e-1)" "unprognostic (5.92e-2)" "unprognostic (1.06e-1)" "unprognostic (2.28e-1)" CD3D "CD3-DELTA, CD3DELTA, T3D" ENSG00000167286 "CD3 delta subunit of T-cell receptor complex" P04234 11 118339075-118342705 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "FDA approved drug targets, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 24 "lymphoid tissue: 809.4" "Cell type enriched" "Detected in some" 10 "T-cells: 566.9" "Cell type enriched" "Detected in single" 427 "leukocyte: 121.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in all" 53 "gdT-cell: 1434.7;MAIT T-cell: 971.2;memory CD4 T-cell: 1184.7;memory CD8 T-cell: 1338.7;naive CD4 T-cell: 1071.7;naive CD8 T-cell: 1320.2;T-reg: 1629.7" "Lineage enriched" "Detected in all" 68 "T-cells: 1629.7" "Cancer enriched" "Detected in some" 8 "Leukemia: 223.2" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Minor Salivary Gland - T-cells, Pancreas - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Skin - T-cells, Spleen - T-cells, Stomach - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB013055, HPA071778" Enhanced Uncertain "Endoplasmic reticulum,Vesicles" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 80: Thymus - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" 12 "Endoplasmic reticulum, Vesicles" "CAB013055: , HPA071778: " "unprognostic (2.77e-3)" "potential prognostic favorable (3.36e-4)" "unprognostic (7.81e-2)" "unprognostic (7.80e-3)" "unprognostic (1.81e-1)" "unprognostic (5.22e-2)" "unprognostic (2.93e-3)" "unprognostic (3.59e-2)" "potential prognostic favorable (1.09e-4)" "unprognostic (4.86e-1)" "unprognostic (7.80e-2)" "unprognostic (3.65e-2)" "unprognostic (8.36e-2)" "unprognostic (3.98e-1)" "unprognostic (4.81e-2)" "unprognostic (3.94e-2)" "unprognostic (3.27e-1)" "unprognostic (3.02e-1)" "unprognostic (4.00e-2)" "unprognostic (1.63e-2)" "unprognostic (4.30e-2)" "unprognostic (9.42e-2)" "unprognostic (1.50e-1)" "unprognostic (3.32e-1)" "unprognostic (3.32e-2)" "unprognostic (2.08e-1)" "unprognostic (1.26e-3)" "unprognostic (1.91e-1)" "unprognostic (9.92e-2)" "unprognostic (2.65e-2)" "unprognostic (4.68e-2)" CD3E "CD3-epsilon, CD3epsilon" ENSG00000198851 "CD3 epsilon subunit of T-cell receptor complex" P07766 11 118304730-118316175 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Adaptive immunity, Immunity" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 16 "lymphoid tissue: 596.2" "Cell type enhanced" "Detected in some" "Innate lymphoid cells: 58.7;NK-cells: 137.0;T-cells: 424.7;Thymocytes: 83.8" "Cell type enriched" "Detected in some" 179 "leukocyte: 199.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 26 "gdT-cell: 491.6;MAIT T-cell: 421.5;memory CD4 T-cell: 415.6;memory CD8 T-cell: 463.4;naive CD4 T-cell: 493.3;naive CD8 T-cell: 502.8;NK-cell: 203.3;T-reg: 427.4" "Group enriched" "Detected in all" 21 "NK-cells: 203.3;T-cells: 502.8" "Cancer enriched" "Detected in some" 8 "Leukemia: 125.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Minor Salivary Gland - T-cells, Pancreas - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Skin - T-cells, Spleen - T-cells, Stomach - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000010, HPA040957, HPA043955, CAB072863, CAB072864" Enhanced Supported "Endoplasmic reticulum,Golgi apparatus,Plasma membrane" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 80: Thymus - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" 38 "Endoplasmic reticulum, Plasma membrane" "Golgi apparatus" "CAB000010: , CAB072863: , CAB072864: , HPA040957: , HPA043955: " "unprognostic (2.34e-2)" "potential prognostic favorable (1.61e-4)" "unprognostic (2.89e-2)" "potential prognostic favorable (2.43e-4)" "unprognostic (1.49e-1)" "unprognostic (1.11e-1)" "unprognostic (3.05e-3)" "unprognostic (8.41e-2)" "potential prognostic favorable (3.77e-4)" "unprognostic (2.18e-1)" "unprognostic (1.70e-1)" "unprognostic (2.67e-2)" "unprognostic (4.50e-2)" "unprognostic (1.28e-2)" "unprognostic (3.27e-2)" "unprognostic (2.30e-2)" "unprognostic (2.25e-1)" "unprognostic (5.00e-1)" "unprognostic (1.44e-1)" "unprognostic (8.79e-2)" "unprognostic (7.73e-2)" "unprognostic (1.22e-1)" "unprognostic (1.47e-1)" "unprognostic (1.82e-1)" "unprognostic (2.31e-2)" "unprognostic (2.26e-1)" "unprognostic (8.54e-3)" "unprognostic (1.20e-1)" "unprognostic (6.85e-2)" "unprognostic (1.29e-1)" "unprognostic (3.39e-2)" CD3G "CD3-GAMMA, CD3GAMMA" ENSG00000160654 "CD3 gamma subunit of T-cell receptor complex" P09693 11 118344344-118355161 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "lymphoid tissue: 88.1" "Cell type enriched" "Detected in some" 8 "T-cells: 299.5" "Cell type enriched" "Detected in single" 470 "leukocyte: 168.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 21 "gdT-cell: 228.7;MAIT T-cell: 135.3;memory CD4 T-cell: 187.4;memory CD8 T-cell: 196.4;naive CD4 T-cell: 192.7;naive CD8 T-cell: 241.8;T-reg: 200.1" "Lineage enriched" "Detected in many" 26 "T-cells: 241.8" "Cancer enriched" "Detected in some" 6 "Leukemia: 19.9" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Minor Salivary Gland - T-cells, Pancreas - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Skin - T-cells, Spleen - T-cells, Stomach - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB017520, HPA038494" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 80: Thymus - Adaptive immune response" "Cluster 6: Non-specific - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" 10 "Plasma membrane, Cytosol" "CAB017520: , HPA038494: " "unprognostic (3.30e-2)" "unprognostic (1.87e-2)" "unprognostic (4.46e-1)" "unprognostic (3.75e-3)" "unprognostic (1.58e-1)" "unprognostic (1.84e-1)" "unprognostic (4.89e-2)" "unprognostic (2.41e-3)" "unprognostic (3.93e-2)" "unprognostic (9.65e-2)" "unprognostic (1.55e-2)" "unprognostic (4.77e-3)" "unprognostic (9.31e-2)" "unprognostic (1.88e-1)" "unprognostic (1.98e-1)" "unprognostic (5.39e-2)" "unprognostic (5.38e-3)" "unprognostic (7.48e-2)" "unprognostic (2.21e-2)" "unprognostic (1.41e-1)" "unprognostic (4.90e-2)" "unprognostic (2.59e-1)" "unprognostic (5.30e-2)" "unprognostic (8.32e-2)" "unprognostic (2.46e-2)" "unprognostic (1.07e-2)" "unprognostic (8.94e-2)" CD4 ENSG00000010610 "CD4 molecule" P01730 12 6786858-6820799 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Adaptive immunity, Host-virus interaction, Immunity" "Host cell receptor for virus entry, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 143.1;lymphoid tissue: 204.2;parathyroid gland: 163.6" "Cell type enhanced" "Detected in many" "cDC: 136.3;Hofbauer cells: 224.0;Kupffer cells: 558.6;Macrophages: 175.1;Microglia: 130.8;monocytes: 112.5;pDCs: 315.1" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 162.0;fibroblast: 71.2;pericyte: 48.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 18 "classical monocyte: 247.4;intermediate monocyte: 241.4;memory CD4 T-cell: 153.8;myeloid DC: 166.4;naive CD4 T-cell: 128.5;non-classical monocyte: 205.2;plasmacytoid DC: 264.3;T-reg: 154.9" "Group enriched" "Detected in many" 20 "dendritic cells: 264.3;monocytes: 247.4;T-cells: 154.9" "Group enriched" "Detected in some" 35 "Leukemia: 40.6;lymphoma: 27.6;Myeloma: 23.9" "Adrenal gland - Macrophages, Minor Salivary Gland - Macrophages, Skeletal muscle - Macrophages, Spleen - Macrophages, Stomach - Macrophages" "Region enriched" "Detected in many" 14 "basal ganglia: 46.2" "Low region specificity" "Detected in many" "CAB000011, HPA004252, HPA004472, CAB068180" Enhanced Supported "Plasma membrane" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 10 "Plasma membrane" "CAB000011: , CAB068180: , HPA004252: , HPA004472: " "unprognostic (2.67e-3)" "unprognostic (8.77e-3)" "unprognostic (1.16e-1)" "unprognostic (6.22e-2)" "unprognostic (1.11e-1)" "unprognostic (7.78e-2)" "unprognostic (4.32e-2)" "unprognostic (2.37e-1)" "unprognostic (1.82e-2)" "unprognostic (2.86e-1)" "unprognostic (1.01e-1)" "unprognostic (2.56e-1)" "unprognostic (1.24e-1)" "unprognostic (7.83e-2)" "unprognostic (5.34e-2)" "unprognostic (1.44e-2)" "unprognostic (1.29e-2)" "unprognostic (1.98e-2)" "unprognostic (3.00e-2)" "unprognostic (2.27e-1)" "unprognostic (2.71e-1)" "unprognostic (2.49e-1)" "unprognostic (5.33e-2)" "unprognostic (4.32e-1)" "unprognostic (1.50e-1)" "unprognostic (1.59e-2)" "unprognostic (5.76e-2)" "unprognostic (1.17e-1)" "unprognostic (5.52e-3)" "unprognostic (5.86e-2)" "unprognostic (3.27e-1)" CD40 "Bp50, p50, TNFRSF5" ENSG00000101017 "CD40 molecule" P25942 20 46118271-46129863 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Immunity Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 52.9" "Cell type enhanced" "Detected in many" "B-cells: 100.5;cDC: 102.8;Epididymal basal cells: 152.2;Vascular endothelial cells: 61.7" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 29.2;pericyte: 32.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 108.3;naive B-cell: 123.7" "Group enriched" "Detected in all" 6 "B-cells: 123.7;monocytes: 34.9" "Cancer enhanced" "Detected in many" "lymphoma: 97.7" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002495, HPA031567, HPA031568, CAB072868, CAB080468" Enhanced Approved "Vesicles,Plasma membrane" "Secreted to blood" Receptor NA NA 705000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 55: Lymphoma - Immune response" "Cluster 82: Dendritic cells - Antigen presentation" 76 Vesicles "Plasma membrane" "CAB002495: , CAB072868: , CAB080468: , HPA031567: , HPA031568: " "unprognostic (3.20e-2)" "unprognostic (1.68e-2)" "unprognostic (1.28e-1)" "unprognostic (1.24e-1)" "unprognostic (3.59e-2)" "unprognostic (5.71e-2)" "potential prognostic unfavorable (6.62e-4)" "unprognostic (7.05e-2)" "unprognostic (1.50e-1)" "unprognostic (2.11e-2)" "unprognostic (2.74e-2)" "unprognostic (1.71e-1)" "unprognostic (6.55e-2)" "unprognostic (8.70e-3)" "unprognostic (3.46e-1)" "unprognostic (2.31e-2)" "unprognostic (3.07e-2)" "unprognostic (1.57e-1)" "unprognostic (2.17e-2)" "unprognostic (1.51e-1)" "unprognostic (2.00e-1)" "unprognostic (9.95e-3)" "unprognostic (3.31e-2)" "unprognostic (1.12e-1)" "unprognostic (3.58e-2)" "unprognostic (1.59e-3)" "unprognostic (5.10e-2)" "unprognostic (3.74e-2)" "unprognostic (5.05e-2)" "unprognostic (6.57e-2)" "unprognostic (4.03e-2)" CD40LG "CD154, CD40-L, CD40L, gp39, hCD40L, HIGM1, IMD3, T-BAM, TNFSF5, TRAP" ENSG00000102245 "CD40 ligand" P29965 X 136648158-136660390 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Cytokine "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 14.1" "Cell type enhanced" "Detected in some" "Innate lymphoid cells: 20.5;Late spermatids: 10.9;Megakaryocyte-Erythroid progenitors: 9.7;Platelets: 35.3;Respiratory ionocytes: 5.1;T-cells: 61.2" "Cell type enriched" "Detected in single" 20 "leukocyte: 19.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 5 "gdT-cell: 26.4;MAIT T-cell: 64.4;memory CD4 T-cell: 80.5;naive CD4 T-cell: 76.3" "Lineage enriched" "Detected in many" 34 "T-cells: 80.5" "Cancer enriched" "Detected in single" 7 "Leukemia: 2.6" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Colon - T-cells, Lung - T-cells, Minor Salivary Gland - T-cells, Prostate - T-cells, Skin - T-cells, Spleen - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045827, HPA072480" Enhanced Approved "Golgi apparatus,Plasma membrane" "Secreted to blood" Cytokine NA NA 776000 14000 "Cluster 11: T-cells - Unknown function" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 6: Non-specific - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" 1 "Golgi apparatus, Plasma membrane" "HPA045827: , HPA072480: " "potential prognostic favorable (2.15e-4)" "unprognostic (7.50e-3)" "unprognostic (2.87e-1)" "unprognostic (2.42e-1)" "unprognostic (2.12e-1)" "unprognostic (4.01e-3)" "unprognostic (1.10e-3)" "unprognostic (1.70e-2)" "unprognostic (2.76e-1)" "unprognostic (1.26e-1)" "unprognostic (1.73e-1)" "unprognostic (6.40e-2)" "unprognostic (2.64e-2)" CD44 "CD44R, CSPG8, HCELL, IN, MC56, MDU2, MDU3, MIC4, Pgp1" ENSG00000026508 "CD44 molecule (Indian blood group)" P16070 11 35138882-35232402 "Blood group antigen proteins, Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cell adhesion" "Blood group antigen, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 469.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 1692.5;cDC: 1408.4;Mast cells: 1993.4;monocytes: 2581.0;Neutrophils: 1651.0;Ocular epithelial cells: 1190.5;Pancreatic acinar cells: 2586.0;Pancreatic duct cells: 1846.1;Suprabasal keratinocytes: 1644.0" "Cell type enhanced" "Detected in many" "astrocyte: 403.2;leukocyte: 474.2;vascular associated smooth muscle cell: 152.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 1400.7" "Adipose subcutaneous - Adipose progenitor cells, Prostate - Urothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000112, CAB000316, HPA005785" Enhanced Supported "Golgi apparatus,Plasma membrane" "Secreted to blood" Receptor NA NA 260000000 200000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 58: Skin - Keratinization" "Cluster 39: Astrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 27 "Plasma membrane" "Golgi apparatus" "CAB000112: , CAB000316: , HPA005785: " "unprognostic (1.93e-3)" "unprognostic (1.85e-1)" "unprognostic (3.84e-1)" "unprognostic (7.75e-2)" "unprognostic (1.18e-1)" "unprognostic (1.07e-1)" "unprognostic (1.02e-3)" "unprognostic (1.90e-2)" "unprognostic (3.00e-2)" "unprognostic (3.19e-1)" "potential prognostic unfavorable (1.71e-4)" "unprognostic (1.76e-2)" "unprognostic (1.32e-3)" "unprognostic (3.08e-3)" "unprognostic (1.73e-1)" "unprognostic (5.04e-2)" "unprognostic (1.25e-2)" "unprognostic (2.49e-1)" "unprognostic (1.76e-1)" "unprognostic (1.03e-1)" "unprognostic (1.27e-1)" "unprognostic (1.77e-3)" "unprognostic (1.44e-2)" "unprognostic (8.40e-2)" "unprognostic (1.58e-2)" "unprognostic (5.89e-3)" "unprognostic (8.97e-2)" "unprognostic (7.15e-2)" "unprognostic (1.25e-1)" "unprognostic (6.97e-2)" "unprognostic (8.74e-2)" CD46 "MCP, MGC26544, MIC10, TLX, TRA2.10" ENSG00000117335 "CD46 molecule" P15529 1 207752037-207795513 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Complement pathway, Fertilization, Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Receptor" "Cancer-related genes, Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 974.8;Salivary acinar cells: 736.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 301.2;eosinophil: 387.4;neutrophil: 404.1" "Lineage enriched" "Detected in all" 5 "granulocytes: 404.1" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in single" "CAB010401, HPA016903" Enhanced Approved "Plasma membrane" NA NA 1900000 "Cluster 35: Neutrophils - Protein binding" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 36: Choroid plexus - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 4 "Plasma membrane" "CAB010401: , HPA016903: " "unprognostic (8.50e-2)" "unprognostic (3.35e-3)" "unprognostic (5.19e-2)" "potential prognostic unfavorable (1.33e-4)" "unprognostic (3.68e-1)" "unprognostic (3.78e-2)" "unprognostic (6.00e-2)" "unprognostic (1.84e-1)" "unprognostic (2.78e-2)" "unprognostic (2.26e-1)" "potential prognostic favorable (1.32e-6)" "unprognostic (9.93e-3)" "unprognostic (4.11e-2)" "unprognostic (4.21e-2)" "unprognostic (3.94e-2)" "unprognostic (2.33e-1)" "unprognostic (6.83e-2)" "unprognostic (1.66e-2)" "unprognostic (1.45e-1)" "unprognostic (1.32e-1)" "unprognostic (2.57e-3)" "unprognostic (1.19e-1)" "unprognostic (7.92e-2)" "unprognostic (1.71e-1)" "unprognostic (2.56e-1)" "unprognostic (2.20e-2)" "unprognostic (2.46e-1)" "unprognostic (8.72e-3)" "unprognostic (1.07e-1)" "unprognostic (1.23e-1)" "unprognostic (4.51e-1)" CD47 "IAP, MER6, OA3" ENSG00000196776 "CD47 molecule" Q08722 3 108043091-108091862 "CD markers, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Angiogenesis, Apoptosis, Cell adhesion, Inflammatory response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 618.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016055, HPA044659" Approved Supported "Vesicles,Plasma membrane" NA NA 210000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 34: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 51: Secretory epithelial cells - Mixed function" 6 "Plasma membrane" Vesicles "CAB016055: , HPA044659: " "unprognostic (2.73e-2)" "unprognostic (5.32e-2)" "unprognostic (1.84e-1)" "unprognostic (1.19e-1)" "unprognostic (6.14e-2)" "unprognostic (9.01e-2)" "unprognostic (2.18e-2)" "unprognostic (4.95e-2)" "unprognostic (1.14e-1)" "unprognostic (3.25e-2)" "unprognostic (8.57e-3)" "unprognostic (4.16e-1)" "unprognostic (2.95e-2)" "potential prognostic unfavorable (1.03e-5)" "unprognostic (1.09e-1)" "unprognostic (5.42e-2)" "unprognostic (1.44e-1)" "potential prognostic unfavorable (9.98e-5)" "unprognostic (1.61e-1)" "unprognostic (1.36e-1)" "unprognostic (2.95e-2)" "unprognostic (2.77e-3)" "unprognostic (1.51e-1)" "unprognostic (2.04e-1)" "unprognostic (1.41e-1)" "unprognostic (1.16e-1)" "unprognostic (3.32e-2)" "unprognostic (6.42e-2)" "unprognostic (2.16e-1)" "potential prognostic favorable (4.20e-4)" "unprognostic (2.13e-2)" CD48 "BCM1, BLAST, hCD48, mCD48, SLAMF2" ENSG00000117091 "CD48 molecule" P09326 1 160678746-160711831 "CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 140.1;lymphoid tissue: 265.6" "Cell type enhanced" "Detected in some" "B-cells: 302.7;cDC: 190.7;Innate lymphoid cells: 122.2;Kupffer cells: 115.8;Macrophages: 82.6;Mast cells: 186.6;Monocyte progenitors: 76.8;monocytes: 316.6;Neutrophils: 294.5;NK-cells: 216.7;Plasma cells: 189.4;T-cells: 310.8" "Cell type enriched" "Detected in some" 144 "leukocyte: 159.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "lymphoma: 243.2;Myeloma: 458.6" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Testis - Early spermatids, Thyroid gland - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002497, HPA055146" Enhanced Approved "Nucleoli fibrillar center,Plasma membrane,Cytosol" "Secreted to blood" "No annotated function" NA NA 1770000 1000000 "Cluster 33: Non-specific - ATP binding" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 55: Lymphoma - Immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 1 "Plasma membrane" "Nucleoli fibrillar center, Cytosol" "CAB002497: , HPA055146: " "unprognostic (5.07e-2)" "potential prognostic favorable (5.81e-4)" "unprognostic (4.94e-2)" "unprognostic (1.10e-2)" "unprognostic (6.75e-2)" "unprognostic (1.60e-1)" "unprognostic (1.83e-2)" "unprognostic (2.21e-1)" "unprognostic (1.36e-2)" "unprognostic (2.51e-1)" "unprognostic (1.27e-2)" "unprognostic (9.56e-2)" "unprognostic (2.17e-1)" "unprognostic (3.53e-2)" "unprognostic (1.77e-2)" "potential prognostic favorable (3.12e-4)" "unprognostic (1.06e-1)" "unprognostic (2.30e-1)" "unprognostic (3.35e-1)" "unprognostic (3.75e-2)" "unprognostic (2.69e-1)" "unprognostic (1.28e-1)" "unprognostic (1.10e-1)" "unprognostic (3.85e-1)" "unprognostic (4.10e-2)" "unprognostic (3.73e-1)" "unprognostic (2.63e-1)" "unprognostic (1.61e-1)" "unprognostic (4.79e-2)" "unprognostic (1.23e-1)" "unprognostic (8.82e-2)" CD5 "LEU1, T1" ENSG00000110448 "CD5 molecule" P06127 11 61102489-61127852 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 43.3" "Cell type enhanced" "Detected in some" "cDC: 10.9;Lacrimal acinar cells: 16.3;Müller glia: 10.9;Retinal bipolar cells: 12.9;Retinal horizontal cells: 16.0;Rod photoreceptor cells: 33.8;T-cells: 65.7" "Cell type enriched" "Detected in some" 19 "leukocyte: 34.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 138.6" "Lineage enriched" "Detected in many" 33 "T-cells: 138.6" "Group enriched" "Detected in some" 7 "Leukemia: 17.3;lymphoma: 23.1" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Prostate - T-cells, Spleen - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB015392, CAB020308, HPA043416, HPA060839" Enhanced NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" 1 "CAB015392: , CAB020308: , HPA043416: , HPA060839: " "unprognostic (4.36e-2)" "unprognostic (1.50e-3)" "unprognostic (7.81e-2)" "unprognostic (6.85e-3)" "unprognostic (3.24e-1)" "unprognostic (1.07e-1)" "potential prognostic favorable (6.45e-6)" "unprognostic (4.58e-1)" "unprognostic (1.89e-1)" "unprognostic (8.29e-2)" "unprognostic (4.34e-3)" "unprognostic (9.24e-3)" "potential prognostic favorable (9.43e-4)" "unprognostic (7.11e-2)" "unprognostic (3.92e-1)" "unprognostic (1.34e-1)" "unprognostic (8.27e-2)" "unprognostic (1.20e-1)" "unprognostic (1.18e-1)" "unprognostic (1.06e-1)" "unprognostic (2.68e-1)" "unprognostic (1.08e-1)" "unprognostic (2.92e-3)" "unprognostic (1.60e-1)" "unprognostic (1.81e-2)" "unprognostic (1.86e-1)" "unprognostic (9.52e-2)" CD52 "CDW52, EDDM5, HE5" ENSG00000169442 "CD52 molecule" P31358 1 26317958-26320523 "Cancer-related genes, CD markers, FDA approved drug targets, Predicted membrane proteins" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 29 "epididymis: 34113.9" "Cell type enriched" "Detected in many" 28 "Epididymal principal cells: 28427.8" "Cell type enriched" "Detected in some" 20 "leukocyte: 85.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 7 "Leukemia: 303.1;lymphoma: 667.3" "Adipose visceral - T-cells, Breast - T-cells, Lung - Macrophages, Prostate - T-cells, Spleen - B-cells (Spleen), Stomach - T-cells, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" "unprognostic (1.36e-1)" "potential prognostic favorable (4.16e-4)" "unprognostic (4.91e-2)" "unprognostic (4.84e-3)" "unprognostic (1.57e-2)" "unprognostic (1.21e-1)" "unprognostic (1.04e-2)" "unprognostic (3.66e-3)" "unprognostic (1.74e-3)" "unprognostic (2.55e-1)" "unprognostic (1.47e-1)" "unprognostic (1.00e-1)" "unprognostic (2.77e-1)" "unprognostic (7.12e-2)" "unprognostic (2.55e-2)" "unprognostic (3.85e-3)" "unprognostic (1.03e-2)" "unprognostic (2.55e-1)" "unprognostic (1.43e-1)" "unprognostic (2.43e-1)" "unprognostic (8.21e-2)" "unprognostic (2.11e-1)" "unprognostic (7.92e-2)" "unprognostic (1.74e-1)" "unprognostic (1.55e-2)" "unprognostic (4.57e-2)" "potential prognostic favorable (9.61e-4)" "unprognostic (3.11e-1)" "unprognostic (5.36e-2)" "unprognostic (1.34e-1)" "unprognostic (2.41e-1)" CD53 "MOX44, TSPAN25" ENSG00000143119 "CD53 molecule" P19397 1 110871188-110899922 "CD markers, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 419.9" "Cell type enhanced" "Detected in many" "B-cells: 453.6;cDC: 277.3;Hematopoietic stem cells: 246.0;Hofbauer cells: 502.9;Innate lymphoid cells: 310.7;Kupffer cells: 416.1;Macrophages: 328.4;Microglia: 368.9;Monocyte progenitors: 347.5;monocytes: 537.5;Neutrophil progenitors: 371.9;Neutrophils: 2135.3;NK-cells: 455.4;pDCs: 229.6;T-cells: 420.2;Thymocytes: 326.9" "Group enriched" "Detected in many" 36 "central nervous system macrophage: 423.9;leukocyte: 382.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 49 "Leukemia: 176.0;lymphoma: 278.2;Myeloma: 139.8" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Pituitary gland - Macrophages, Skeletal muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047216 Enhanced NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 57 "HPA047216: " "unprognostic (1.96e-1)" "unprognostic (2.30e-2)" "unprognostic (3.33e-2)" "unprognostic (2.55e-2)" "unprognostic (5.67e-2)" "unprognostic (1.79e-1)" "unprognostic (4.61e-2)" "unprognostic (7.63e-2)" "unprognostic (5.55e-2)" "unprognostic (4.64e-2)" "unprognostic (1.07e-2)" "unprognostic (3.83e-1)" "unprognostic (2.69e-1)" "unprognostic (1.21e-1)" "unprognostic (1.15e-1)" "unprognostic (1.42e-2)" "unprognostic (9.66e-2)" "unprognostic (1.34e-1)" "unprognostic (4.37e-1)" "unprognostic (7.09e-2)" "unprognostic (1.73e-1)" "unprognostic (1.10e-1)" "unprognostic (1.39e-2)" "unprognostic (2.24e-1)" "unprognostic (4.66e-2)" "unprognostic (8.60e-2)" "unprognostic (1.79e-2)" "unprognostic (1.77e-1)" "unprognostic (2.13e-2)" "unprognostic (3.19e-1)" "unprognostic (2.36e-1)" CD55 "CR, CROM, DAF, TC" ENSG00000196352 "CD55 molecule (Cromer blood group)" P08174 1 207321519-207386804 "Blood group antigen proteins, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Complement pathway, Host-virus interaction, Immunity, Innate immunity" "Blood group antigen, Host cell receptor for virus entry, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 2487.6;Epicardial cells: 1903.5;Esophageal apical cells: 1430.3;Neutrophils: 7705.1;Ocular epithelial cells: 1980.0" "Cell type enhanced" "Detected in all" "leukocyte: 199.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 653.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 1, Spleen - Neutrophils_2, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "HPA002190, CAB010454, HPA024386" Enhanced "Secreted to blood" "Complement pathway" NA No 32300000 16000000 "Cluster 35: Neutrophils - Protein binding" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 1 "CAB010454: , HPA002190: , HPA024386: " "unprognostic (4.12e-1)" "unprognostic (7.61e-2)" "unprognostic (9.07e-2)" "unprognostic (3.32e-1)" "unprognostic (6.26e-2)" "unprognostic (2.24e-2)" "unprognostic (2.62e-2)" "unprognostic (4.30e-2)" "unprognostic (5.27e-2)" "unprognostic (1.33e-1)" "unprognostic (1.07e-1)" "unprognostic (1.19e-2)" "potential prognostic unfavorable (3.47e-6)" "unprognostic (3.46e-2)" "unprognostic (4.78e-2)" "unprognostic (1.07e-2)" "unprognostic (2.37e-1)" "unprognostic (5.31e-3)" "unprognostic (4.16e-1)" "unprognostic (3.13e-2)" "potential prognostic unfavorable (6.72e-5)" "unprognostic (4.58e-2)" "unprognostic (4.57e-2)" "unprognostic (1.67e-1)" "unprognostic (4.25e-2)" "unprognostic (1.00e-1)" "unprognostic (1.82e-1)" "unprognostic (1.69e-1)" "unprognostic (1.89e-1)" "unprognostic (4.43e-2)" "unprognostic (6.70e-2)" CD58 LFA3 ENSG00000116815 "CD58 molecule" P19256 1 116514534-116571039 "CD markers, Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "cDC: 403.1;Macrophages: 219.4;monocytes: 328.1;Neutrophils: 768.2;Ocular epithelial cells: 220.7" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 123.4;endothelial cell: 93.1;leukocyte: 127.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 3300000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 1 "unprognostic (2.75e-1)" "unprognostic (7.47e-2)" "unprognostic (1.08e-1)" "unprognostic (2.02e-1)" "unprognostic (9.52e-3)" "unprognostic (1.22e-1)" "unprognostic (2.20e-2)" "potential prognostic unfavorable (2.29e-6)" "unprognostic (3.82e-1)" "unprognostic (1.57e-1)" "unprognostic (1.65e-3)" "unprognostic (3.20e-1)" "unprognostic (1.42e-1)" "potential prognostic unfavorable (8.97e-7)" "unprognostic (2.87e-1)" "unprognostic (1.09e-1)" "unprognostic (3.59e-3)" "unprognostic (2.65e-1)" "unprognostic (2.13e-1)" "unprognostic (1.79e-1)" "unprognostic (1.44e-1)" "validated prognostic unfavorable (7.68e-5)" "validated prognostic unfavorable (3.32e-4)" "unprognostic (1.67e-1)" "unprognostic (3.84e-1)" "unprognostic (1.23e-1)" "unprognostic (1.70e-1)" "unprognostic (2.50e-1)" "unprognostic (1.20e-1)" "unprognostic (2.74e-1)" "unprognostic (1.39e-1)" CD59 "16.3A5, EJ16, EJ30, EL32, G344, MIC11, MIN1, MIN2, MIN3, MSK21, p18-20" ENSG00000085063 "CD59 molecule (CD59 blood group)" P13987 11 33703010-33736479 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bergmann glia: 83.2;Choroid plexus epithelial cells: 92.4;Other brain neurons: 82.9" "Cell type enhanced" "Detected in all" "endothelial cell: 276.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "CAB001448, HPA026494" Supported Uncertain "Golgi apparatus,Vesicles" "Intracellular and membrane" "No annotated function" NA NA 33000000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 44: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 104: Brain endothelial cells - Blood brain barrier" 10 "Golgi apparatus, Vesicles" "CAB001448: , HPA026494: " "unprognostic (1.58e-1)" "unprognostic (2.10e-2)" "unprognostic (1.83e-2)" "unprognostic (4.96e-3)" "unprognostic (6.20e-2)" "unprognostic (8.60e-3)" "unprognostic (5.49e-3)" "unprognostic (2.50e-2)" "potential prognostic unfavorable (9.32e-4)" "unprognostic (1.11e-2)" "potential prognostic favorable (1.47e-8)" "unprognostic (1.86e-3)" "unprognostic (3.68e-3)" "unprognostic (1.11e-1)" "unprognostic (1.18e-2)" "unprognostic (1.29e-1)" "unprognostic (3.74e-3)" "unprognostic (5.73e-3)" "unprognostic (3.97e-3)" "unprognostic (1.01e-1)" "unprognostic (2.37e-2)" "unprognostic (1.70e-3)" "unprognostic (2.67e-2)" "unprognostic (7.11e-2)" "unprognostic (3.60e-2)" "unprognostic (9.50e-2)" "unprognostic (1.49e-1)" "potential prognostic unfavorable (6.25e-5)" "unprognostic (1.71e-1)" "unprognostic (9.44e-2)" "unprognostic (2.18e-1)" CD5L "API6, Spalpha" ENSG00000073754 "CD5 molecule like" O43866 1 157830911-157898256 "Plasma proteins, Predicted secreted proteins" "Apoptosis, Immunity, Inflammatory response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "lymphoid tissue: 540.1" "Group enriched" "Detected in some" 7 "Hofbauer cells: 633.8;Kupffer cells: 1539.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Liver Hepatocellular Carcinoma (TCGA): 6.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Kupffer cells, Spleen - Macrophages" "Not detected" "Not detected" "Not detected" "Not detected" "HPA065686, HPA068384" Enhanced "Secreted to blood" Immunity NA NA 4030000000 3800000000 "Cluster 66: Lymphoid tissue - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" "HPA065686: , HPA068384: " "unprognostic (3.38e-3)" "unprognostic (3.12e-2)" "potential prognostic favorable (3.92e-5)" "unprognostic (2.69e-2)" "unprognostic (1.53e-1)" CD6 Tp120 ENSG00000013725 "CD6 molecule" P30203 11 60971680-61020377 "CD markers, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Cell adhesion, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 12.6;lymphoid tissue: 40.4" "Cell type enriched" "Detected in many" 7 "T-cells: 196.7" "Cell type enriched" "Detected in many" 29 "leukocyte: 129.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 33 "gdT-cell: 27.8;MAIT T-cell: 24.7;memory CD4 T-cell: 51.5;memory CD8 T-cell: 48.4;naive CD4 T-cell: 34.5;naive CD8 T-cell: 25.2;T-reg: 25.5" "Lineage enriched" "Detected in many" 50 "T-cells: 51.5" "Group enriched" "Detected in some" 10 "Leukemia: 10.8;lymphoma: 11.0" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Minor Salivary Gland - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Spleen - T-cells, Stomach - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB002489, CAB016252" Enhanced "Secreted to blood" Immunity NA NA 5270000 21000 "Cluster 11: T-cells - Unknown function" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" 7 "CAB002489: , CAB016252: " "unprognostic (9.32e-2)" "potential prognostic favorable (2.12e-4)" "unprognostic (1.43e-2)" "potential prognostic favorable (7.70e-5)" "unprognostic (2.21e-1)" "unprognostic (2.29e-1)" "potential prognostic favorable (1.42e-5)" "unprognostic (8.82e-2)" "unprognostic (2.61e-1)" "unprognostic (6.07e-3)" "unprognostic (8.79e-3)" "potential prognostic favorable (6.48e-4)" "unprognostic (1.22e-2)" "unprognostic (9.83e-2)" "unprognostic (2.17e-1)" "unprognostic (3.22e-1)" "unprognostic (4.07e-3)" "unprognostic (1.96e-2)" "unprognostic (4.06e-1)" "unprognostic (3.28e-2)" "unprognostic (1.73e-1)" "unprognostic (5.57e-2)" "unprognostic (2.98e-1)" "potential prognostic favorable (6.31e-4)" "unprognostic (7.20e-2)" "unprognostic (3.69e-2)" "unprognostic (1.09e-1)" "unprognostic (1.14e-1)" CD63 "ME491, MLA1, TSPAN30" ENSG00000135404 "CD63 molecule" P08962 12 55725323-55729707 "CD markers, Plasma proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 3664.9;Esophageal apical cells: 2986.2;Extravillous trophoblasts: 3956.6;Hofbauer cells: 3923.7;Syncytiotrophoblasts: 3670.6" "Cell type enhanced" "Detected in all" "pericyte: 302.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 1861.6" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010088, CAB026356, HPA073506" Supported Supported Vesicles "Intracellular and membrane" Transport NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 12: Non-specific - Vasculature" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 36 Vesicles "CAB026356: , HPA010088: , HPA073506: " "unprognostic (8.38e-2)" "unprognostic (1.82e-2)" "unprognostic (2.59e-1)" "unprognostic (8.10e-2)" "unprognostic (1.59e-1)" "unprognostic (3.29e-2)" "unprognostic (9.37e-3)" "potential prognostic unfavorable (7.36e-4)" "unprognostic (4.40e-3)" "unprognostic (4.85e-2)" "unprognostic (8.60e-3)" "unprognostic (6.06e-2)" "unprognostic (1.62e-1)" "potential prognostic unfavorable (6.81e-6)" "unprognostic (1.54e-3)" "unprognostic (1.40e-1)" "unprognostic (7.14e-2)" "unprognostic (8.02e-2)" "unprognostic (1.02e-2)" "unprognostic (1.64e-1)" "unprognostic (5.59e-2)" "unprognostic (9.76e-2)" "unprognostic (4.30e-2)" "unprognostic (1.73e-1)" "potential prognostic unfavorable (1.36e-4)" "unprognostic (9.64e-2)" "unprognostic (8.15e-2)" "unprognostic (3.18e-2)" "unprognostic (1.50e-1)" "unprognostic (2.87e-3)" "unprognostic (3.90e-2)" CD68 "DKFZp686M18236, GP110, LAMP4, SCARD1" ENSG00000129226 "CD68 molecule" P34810 17 7579491-7582111 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 337.0;lymphoid tissue: 349.0" "Cell type enhanced" "Detected in many" "cDC: 36.0;Enterocytes: 171.4;Esophageal apical cells: 68.8;Hofbauer cells: 246.3;Kupffer cells: 280.8;Macrophages: 65.9;Microglia: 72.0;monocytes: 61.2;Platelets: 35.1" "Cell type enriched" "Detected in some" 5 "central nervous system macrophage: 88.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 3264.9;intermediate monocyte: 3664.2;non-classical monocyte: 3764.8" "Group enriched" "Detected in all" 11 "dendritic cells: 1382.0;monocytes: 3764.8" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Lung - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Spleen - Macrophages, Testis - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in all" "CAB000051, CAB000066, HPA048982, CAB072861, CAB072862" Enhanced Supported "Golgi apparatus,Vesicles" NA NA 23000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 11 "Golgi apparatus, Vesicles" "CAB000051: , CAB000066: , CAB072861: , CAB072862: , HPA048982: " "unprognostic (9.25e-2)" "unprognostic (1.97e-1)" "unprognostic (5.80e-2)" "unprognostic (3.41e-2)" "unprognostic (1.47e-1)" "unprognostic (3.15e-1)" "unprognostic (1.53e-2)" "unprognostic (1.00e-2)" "unprognostic (8.87e-2)" "unprognostic (6.68e-2)" "unprognostic (2.00e-2)" "unprognostic (1.48e-1)" "unprognostic (2.48e-1)" "unprognostic (1.53e-3)" "unprognostic (2.68e-1)" "unprognostic (5.75e-2)" "unprognostic (9.00e-3)" "unprognostic (1.58e-2)" "unprognostic (3.51e-2)" "unprognostic (1.26e-2)" "unprognostic (2.58e-1)" "unprognostic (2.69e-3)" "unprognostic (1.10e-1)" "unprognostic (1.82e-1)" "unprognostic (1.24e-1)" "unprognostic (2.09e-1)" "unprognostic (8.14e-2)" "unprognostic (1.82e-1)" "unprognostic (9.50e-3)" "unprognostic (2.51e-1)" "unprognostic (2.14e-1)" CD69 CLEC2C ENSG00000110848 "CD69 molecule" Q07108 12 9752486-9760901 "CD markers, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 159.6;lymphoid tissue: 88.3" "Group enriched" "Detected in many" 5 "B-cells: 1058.2;Hematopoietic stem cells: 1802.1;Innate lymphoid cells: 1663.3;Mast cells: 3282.2;Megakaryocyte progenitors: 1010.7;Megakaryocyte-Erythroid progenitors: 1084.5;NK-cells: 1210.9;T-cells: 1522.4" "Group enriched" "Detected in some" 168 "central nervous system macrophage: 124.4;leukocyte: 405.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "NK-cells: 26.8;T-cells: 30.8" "Group enriched" "Detected in some" 6 "Leukemia: 45.9;lymphoma: 25.6" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Kidney - T-cells, Minor Salivary Gland - T-cells, Stomach - Fibroblasts, Thyroid gland - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB002503, HPA050525" Enhanced NA NA "Cluster 24: Non-specific - Transcription" "Cluster 15: Bone marrow - Innate immune response" "Cluster 8: Immune cells - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 58: Mast cells - Allergic inflammatory responses" 13 "CAB002503: , HPA050525: " "unprognostic (7.30e-2)" "potential prognostic favorable (3.45e-4)" "unprognostic (1.36e-2)" "unprognostic (8.81e-3)" "unprognostic (8.19e-2)" "unprognostic (2.21e-1)" "unprognostic (3.45e-2)" "unprognostic (5.57e-2)" "unprognostic (7.13e-3)" "unprognostic (4.90e-3)" "unprognostic (3.02e-1)" "unprognostic (4.20e-2)" "unprognostic (2.12e-1)" "unprognostic (9.56e-3)" "unprognostic (1.19e-2)" "unprognostic (2.81e-3)" "unprognostic (3.79e-1)" "unprognostic (3.39e-1)" "unprognostic (2.21e-1)" "unprognostic (1.41e-1)" "unprognostic (2.15e-1)" "unprognostic (1.15e-2)" "unprognostic (1.06e-1)" "unprognostic (1.14e-1)" "unprognostic (4.50e-2)" "potential prognostic favorable (1.90e-4)" "unprognostic (4.77e-3)" "unprognostic (3.72e-2)" "unprognostic (2.54e-2)" "unprognostic (4.89e-2)" "unprognostic (1.03e-1)" CD7 "GP40, LEU-9, Tp40, TP41" ENSG00000173762 "CD7 molecule" P09564 17 82314868-82317608 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 26.9;lymphoid tissue: 51.1" "Group enriched" "Detected in many" 17 "Innate lymphoid cells: 332.7;NK-cells: 774.1;T-cells: 306.7;Thymocytes: 372.7" "Cell type enriched" "Detected in some" 21 "leukocyte: 196.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "NK-cell: 232.4" "Group enriched" "Detected in many" 22 "NK-cells: 232.4;T-cells: 71.8" "Group enriched" "Detected in some" 6 "Leukemia: 50.4;liver cancer: 16.7;Myeloma: 21.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Heart muscle - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Pancreas - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Thyroid gland - T-cells" "Region enhanced" "Detected in some" "cerebral cortex: 3.2" "Not detected" "Not detected" "CAB002594, HPA039079" Enhanced NA NA "Cluster 1: T-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 44: Non-specific - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 17 "CAB002594: , HPA039079: " "unprognostic (1.80e-3)" "unprognostic (5.84e-3)" "unprognostic (9.08e-2)" "unprognostic (1.69e-3)" "unprognostic (1.89e-1)" "unprognostic (1.51e-1)" "unprognostic (1.19e-3)" "unprognostic (1.07e-3)" "unprognostic (8.01e-2)" "potential prognostic unfavorable (3.32e-4)" "unprognostic (2.61e-1)" "unprognostic (2.02e-3)" "unprognostic (4.51e-2)" "unprognostic (1.66e-1)" "unprognostic (2.96e-1)" "unprognostic (2.57e-1)" "unprognostic (1.79e-1)" "unprognostic (2.24e-1)" "unprognostic (7.95e-3)" "unprognostic (1.87e-2)" "unprognostic (1.86e-1)" "unprognostic (2.72e-2)" "unprognostic (3.12e-1)" "unprognostic (5.43e-2)" "unprognostic (8.98e-2)" "potential prognostic favorable (9.26e-6)" "unprognostic (1.03e-1)" "unprognostic (3.44e-2)" "unprognostic (1.39e-1)" "unprognostic (5.28e-3)" CD70 "CD27L, CD27LG, TNFSF7" ENSG00000125726 "CD70 molecule" P32970 19 6583183-6604103 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 3.2" "Cell type enhanced" "Detected in some" "B-cells: 75.9;cDC: 8.8;Epididymal basal cells: 25.8;Epididymal efferent duct ciliated cells: 17.6;Fibro-adipogenic progenitors: 11.7;Fibroblasts: 13.6;Plasma cells: 36.1;T-cells: 32.5" "Cell type enriched" "Detected in some" 8 "leukocyte: 11.6" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 97.1" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "T-reg: 44.3" "Group enriched" "Detected in many" 35 "B-cells: 24.3;T-cells: 44.3" "Cancer enhanced" "Detected in many" "Kidney cancer: 386.8" "Thyroid gland - T-cells" "Region enriched" "Detected in single" 25 "cerebellum: 11.3" "Low region specificity" "Detected in many" HPA046582 Uncertain Nucleoplasm NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 25: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 84 Nucleoplasm "HPA046582: " "unprognostic (1.40e-1)" "unprognostic (1.92e-1)" "unprognostic (4.64e-1)" "unprognostic (1.02e-1)" "unprognostic (1.35e-1)" "unprognostic (1.19e-1)" "unprognostic (7.02e-3)" "unprognostic (1.22e-1)" "unprognostic (9.36e-2)" "unprognostic (6.66e-2)" "unprognostic (2.34e-1)" "unprognostic (1.95e-3)" "unprognostic (1.81e-1)" "unprognostic (9.92e-3)" "unprognostic (1.79e-2)" "unprognostic (2.69e-2)" "unprognostic (4.14e-1)" "unprognostic (2.85e-1)" "unprognostic (7.29e-2)" "potential prognostic unfavorable (3.56e-4)" "unprognostic (1.26e-1)" "unprognostic (1.21e-2)" "unprognostic (6.05e-3)" "unprognostic (3.00e-2)" "unprognostic (1.81e-1)" "unprognostic (2.71e-1)" "unprognostic (3.29e-1)" CD72 "CD72b, LYB2" ENSG00000137101 "CD72 molecule" P21854 9 35609982-35646810 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "lymphoid tissue: 60.4" "Cell type enhanced" "Detected in many" "B-cells: 89.0;cDC: 55.1;Kupffer cells: 65.6;Macrophages: 46.3;monocytes: 29.7;NK-cells: 42.4;Thymocytes: 29.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "memory B-cell: 233.6;naive B-cell: 413.2" "Lineage enriched" "Detected in all" 20 "B-cells: 413.2" "Group enriched" "Detected in some" 32 "Leukemia: 20.9;lymphoma: 39.1" "Prostate - T-cells" "Region enriched" "Detected in single" 7 "basal ganglia: 4.1" "Low region specificity" "Detected in some" "CAB002505, HPA044658" Enhanced Uncertain Nucleoplasm,Mitochondria NA NA "Cluster 34: B-cells - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 35: RS4;11 - Unknown function" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 16 "Nucleoplasm, Mitochondria" "CAB002505: , HPA044658: " "unprognostic (7.25e-2)" "unprognostic (3.59e-1)" "unprognostic (3.32e-2)" "unprognostic (4.26e-2)" "unprognostic (3.40e-3)" "unprognostic (2.03e-2)" "unprognostic (1.48e-2)" "unprognostic (1.74e-1)" "unprognostic (2.45e-1)" "unprognostic (1.77e-1)" "unprognostic (2.78e-3)" "unprognostic (1.06e-1)" "unprognostic (5.58e-2)" "unprognostic (2.31e-2)" "unprognostic (4.94e-2)" "unprognostic (2.70e-1)" "unprognostic (2.75e-2)" "unprognostic (1.21e-1)" "unprognostic (3.97e-1)" "unprognostic (9.33e-2)" "unprognostic (1.19e-1)" "unprognostic (6.16e-2)" "unprognostic (7.46e-3)" "unprognostic (2.20e-1)" "unprognostic (2.37e-2)" "unprognostic (4.71e-2)" "unprognostic (1.17e-2)" "unprognostic (2.22e-1)" "unprognostic (1.80e-2)" "unprognostic (3.93e-1)" "unprognostic (5.06e-2)" CD74 "CLIP, DHLAG" ENSG00000019582 "CD74 molecule" P04233 5 150401637-150412969 "Cancer-related genes, CD markers, Disease related genes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Adaptive immunity, Immunity" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 4925.3" "Cell type enhanced" "Detected in many" "B-cells: 3923.1;cDC: 14449.7;Endometrial secretory cells: 1799.7;Enterocytes: 4957.0;Kupffer cells: 5170.7;Macrophages: 5932.6;monocytes: 2326.9;pDCs: 4090.1" "Cell type enriched" "Detected in many" 5 "central nervous system macrophage: 1596.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 11129.6;intermediate monocyte: 16174.8;memory B-cell: 27121.2;myeloid DC: 23965.9;naive B-cell: 28192.5;non-classical monocyte: 8146.1;plasmacytoid DC: 17015.9" "Group enriched" "Detected in all" 6 "B-cells: 28192.5;dendritic cells: 23965.9;monocytes: 16174.8" "Group enriched" "Detected in many" 7 "Leukemia: 998.7;lymphoma: 3214.7;Myeloma: 1807.4;skin cancer: 961.7" "Adipose visceral - T-cells, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002506, HPA010592, CAB079994" Enhanced Supported "Golgi apparatus" "Secreted to blood" Immunity NA NA 120000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 82: Dendritic cells - Antigen presentation" 19 "Golgi apparatus" "CAB002506: , CAB079994: , HPA010592: " "unprognostic (1.93e-3)" "potential prognostic favorable (9.48e-5)" "unprognostic (7.99e-2)" "unprognostic (1.92e-2)" "unprognostic (2.67e-1)" "unprognostic (3.10e-1)" "unprognostic (6.11e-2)" "unprognostic (1.82e-1)" "unprognostic (2.78e-2)" "unprognostic (2.35e-1)" "unprognostic (3.17e-1)" "unprognostic (4.14e-1)" "unprognostic (3.94e-2)" "unprognostic (3.54e-1)" "unprognostic (2.84e-2)" "unprognostic (1.12e-3)" "unprognostic (9.15e-2)" "unprognostic (9.54e-2)" "unprognostic (1.95e-1)" "unprognostic (2.52e-1)" "unprognostic (1.51e-2)" "unprognostic (2.89e-2)" "unprognostic (1.21e-1)" "unprognostic (2.11e-1)" "unprognostic (1.13e-1)" "unprognostic (2.34e-2)" "unprognostic (2.56e-2)" "unprognostic (1.05e-1)" "unprognostic (5.36e-2)" "unprognostic (2.53e-1)" "unprognostic (2.47e-3)" CD79A "Ig-alpha, IGA, IGAlpha, MB-1, MB1" ENSG00000105369 "CD79a molecule" P11912 19 41877279-41881372 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 157.7;lymphoid tissue: 510.4" "Group enriched" "Detected in some" 13 "B-cells: 683.6;Plasma cells: 686.7" "Cell type enriched" "Detected in single" 39 "leukocyte: 9.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 38 "memory B-cell: 1278.3;naive B-cell: 1462.8" "Lineage enriched" "Detected in all" 40 "B-cells: 1462.8" "Cancer enriched" "Detected in many" 4 "lymphoma: 867.0" "Breast - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Skin - Plasma cells, Spleen - B-cells (Spleen), Stomach - Plasma cells, Thyroid gland - Plasma cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB000019, HPA056444" Enhanced NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 67: Plasma cells - Plasma cell differentiation" 166 "CAB000019: , HPA056444: " "unprognostic (6.14e-2)" "potential prognostic favorable (4.61e-6)" "unprognostic (1.62e-1)" "unprognostic (3.28e-2)" "unprognostic (1.86e-1)" "unprognostic (2.17e-1)" "potential prognostic favorable (3.21e-5)" "unprognostic (8.87e-2)" "unprognostic (5.96e-3)" "unprognostic (1.59e-1)" "unprognostic (1.47e-3)" "unprognostic (2.47e-2)" "unprognostic (6.52e-2)" "unprognostic (1.28e-3)" "unprognostic (1.98e-2)" "unprognostic (4.28e-1)" "unprognostic (6.97e-2)" "unprognostic (4.94e-3)" "unprognostic (6.71e-2)" "unprognostic (3.39e-1)" "unprognostic (2.12e-1)" "unprognostic (1.06e-1)" "unprognostic (3.62e-3)" "unprognostic (1.20e-1)" "unprognostic (6.73e-3)" "unprognostic (2.59e-2)" "unprognostic (1.98e-1)" "unprognostic (1.26e-1)" "unprognostic (2.99e-1)" CD79B "B29, Ig-beta, IGB, Igbeta" ENSG00000007312 "CD79b molecule" P40259 17 63928738-63932336 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 247.5" "Cell type enriched" "Detected in some" 7 "B-cells: 18.6" "Group enriched" "Detected in some" 5 "fibroblast: 8.8;leukocyte: 18.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in all" 4 "memory B-cell: 1119.4;naive B-cell: 1488.8" "Lineage enriched" "Detected in all" 5 "B-cells: 1488.8" "Cancer enriched" "Detected in some" 6 "lymphoma: 657.0" "Pituitary gland - Somatotropes, Spleen - B-cells (Spleen)" "Not detected" "Not detected" "Not detected" "Not detected" "HPA009178, CAB009751, HPA044107" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 102: Non-specific - Mixed function" 4 "Plasma membrane" "Nucleoplasm, Cytosol" "CAB009751: , HPA009178: , HPA044107: " "unprognostic (1.46e-1)" "unprognostic (1.55e-2)" "potential prognostic favorable (2.92e-5)" "potential prognostic favorable (3.09e-4)" "unprognostic (1.18e-1)" "unprognostic (1.67e-1)" "potential prognostic unfavorable (4.18e-4)" "unprognostic (1.78e-1)" "potential prognostic favorable (4.85e-4)" "unprognostic (1.39e-1)" "potential prognostic favorable (2.74e-4)" "unprognostic (1.70e-2)" "potential prognostic unfavorable (3.33e-4)" "unprognostic (1.82e-1)" "unprognostic (2.64e-2)" "potential prognostic favorable (2.91e-4)" "unprognostic (1.02e-1)" "unprognostic (7.09e-2)" "unprognostic (8.64e-2)" "unprognostic (1.95e-3)" "unprognostic (1.56e-1)" "unprognostic (1.37e-1)" "unprognostic (2.07e-1)" "unprognostic (3.06e-2)" "unprognostic (5.15e-2)" "unprognostic (5.97e-2)" "unprognostic (4.42e-3)" "unprognostic (1.85e-1)" "unprognostic (7.89e-2)" "unprognostic (1.05e-1)" "unprognostic (2.47e-1)" CD80 "B7-1, B7.1, CD28LG, CD28LG1" ENSG00000121594 "CD80 molecule" P33681 3 119524293-119559614 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lung: 2.8;lymphoid tissue: 6.4" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 5.1;B-cells: 22.4;cDC: 30.8;Kupffer cells: 18.4;Macrophages: 23.2;Megakaryocytes: 6.2;monocytes: 7.9;Retinal horizontal cells: 6.0" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 4.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.4;T-reg: 1.3" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in some" 5 "lymphoma: 19.6" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB025368, HPA050092" Enhanced "Intracellular and membrane" Receptor NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 8: Immune cells - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 82: Dendritic cells - Antigen presentation" 6 "CAB025368: , HPA050092: " "unprognostic (2.18e-1)" "unprognostic (7.63e-2)" "unprognostic (4.98e-2)" "unprognostic (1.46e-1)" "unprognostic (9.23e-2)" "unprognostic (1.86e-1)" "unprognostic (1.93e-1)" "unprognostic (2.59e-3)" "unprognostic (2.58e-2)" "unprognostic (8.67e-2)" "unprognostic (1.04e-1)" "unprognostic (1.83e-2)" "potential prognostic unfavorable (9.01e-5)" "unprognostic (1.87e-2)" "unprognostic (3.67e-1)" "unprognostic (1.25e-2)" CD81 "TAPA-1, TAPA1, TSPAN28" ENSG00000110651 "CD81 molecule" P60033 11 2376177-2397802 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Adaptive immunity, Host-virus interaction, Immunity" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Breast lactating cells: 1123.5;Smooth muscle cells: 1084.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 149.3;naive B-cell: 137.6" "Lineage enriched" "Detected in all" 4 "B-cells: 149.3" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002507, HPA007234" Supported Approved "Plasma membrane,Cytosol" NA NA 1300000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 74: Non-specific - Signal transduction" "Cluster 19: Astrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 50 "Plasma membrane" Cytosol "CAB002507: , HPA007234: " "unprognostic (2.98e-1)" "unprognostic (8.15e-2)" "unprognostic (1.47e-2)" "unprognostic (5.43e-2)" "unprognostic (1.92e-2)" "unprognostic (1.74e-1)" "potential prognostic unfavorable (3.91e-4)" "unprognostic (1.41e-2)" "unprognostic (3.55e-2)" "unprognostic (1.09e-1)" "potential prognostic favorable (4.91e-5)" "unprognostic (2.80e-2)" "unprognostic (2.37e-1)" "unprognostic (1.13e-1)" "unprognostic (1.03e-3)" "unprognostic (2.04e-2)" "unprognostic (1.78e-1)" "unprognostic (4.62e-3)" "unprognostic (1.74e-1)" "unprognostic (1.59e-1)" "unprognostic (1.76e-1)" "unprognostic (7.15e-3)" "unprognostic (1.89e-1)" "unprognostic (5.10e-2)" "unprognostic (2.19e-2)" "unprognostic (2.37e-2)" "unprognostic (2.19e-1)" "unprognostic (1.87e-2)" "unprognostic (1.22e-1)" "unprognostic (1.03e-1)" "unprognostic (4.62e-2)" CD82 "IA4, KAI1, R2, ST6, TSPAN27" ENSG00000085117 "CD82 molecule" P27701 11 44564427-44620358 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 223.6;Esophageal apical cells: 253.9;Esophageal basal cells: 268.7;Esophageal suprabasal cells: 393.4;Mast cells: 244.1;Neutrophils: 552.1;Prostatic club cells: 229.7" "Cell type enhanced" "Detected in many" "oligodendrocyte: 61.3;oligodendrocyte precursor cell: 171.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 537.1" "Group enriched" "Detected in all" 6 "B-cells: 308.8;granulocytes: 537.1;T-cells: 172.7" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Spleen - Macrophages" "Region enhanced" "Detected in all" "white matter: 210.9" "Low region specificity" "Detected in all" "CAB002508, HPA028900, HPA061418" Supported Uncertain Vesicles NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 9 Vesicles "CAB002508: , HPA028900: , HPA061418: " "unprognostic (2.21e-1)" "unprognostic (1.71e-1)" "unprognostic (2.53e-2)" "unprognostic (2.22e-2)" "unprognostic (1.40e-1)" "unprognostic (1.15e-1)" "unprognostic (2.98e-1)" "unprognostic (7.51e-2)" "unprognostic (4.26e-2)" "unprognostic (1.43e-1)" "potential prognostic unfavorable (1.22e-6)" "unprognostic (1.37e-2)" "unprognostic (1.53e-1)" "unprognostic (6.09e-2)" "unprognostic (7.51e-2)" "unprognostic (8.03e-2)" "unprognostic (3.65e-2)" "unprognostic (2.86e-2)" "unprognostic (7.81e-3)" "unprognostic (2.53e-1)" "unprognostic (9.93e-2)" "unprognostic (4.21e-2)" "unprognostic (4.15e-2)" "unprognostic (5.63e-2)" "unprognostic (9.51e-2)" "unprognostic (8.69e-3)" "unprognostic (1.89e-1)" "unprognostic (1.13e-2)" "unprognostic (6.01e-2)" "unprognostic (8.35e-2)" "unprognostic (2.53e-1)" CD83 "BL11, HB15" ENSG00000112149 "CD83 molecule" Q01151 6 14117256-14136918 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 197.9" "Cell type enhanced" "Detected in many" "B-cells: 1196.9;cDC: 2003.3;Hofbauer cells: 406.0;Innate lymphoid cells: 423.2;Kupffer cells: 379.2;Macrophages: 1090.5;Mast cells: 579.1;monocytes: 1088.1;Neutrophils: 633.3;Pancreatic duct cells: 412.5;pDCs: 724.4" "Group enriched" "Detected in all" 5 "central nervous system macrophage: 261.1;leukocyte: 73.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in all" 5 "lymphoma: 133.1" "Adrenal gland - Adrenal cortex cells, Breast - T-cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002509, HPA041454, HPA064421" Enhanced Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Plasma membrane" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 44: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 82: Dendritic cells - Antigen presentation" 12 "Nucleoplasm, Plasma membrane" "Nucleoli, Golgi apparatus" "CAB002509: , HPA041454: , HPA064421: " "unprognostic (1.03e-1)" "unprognostic (1.61e-2)" "unprognostic (4.92e-2)" "unprognostic (2.91e-2)" "unprognostic (3.91e-2)" "unprognostic (8.31e-3)" "unprognostic (3.70e-2)" "unprognostic (1.04e-1)" "unprognostic (2.47e-2)" "unprognostic (3.43e-1)" "potential prognostic favorable (6.59e-5)" "unprognostic (5.49e-2)" "potential prognostic favorable (6.34e-4)" "unprognostic (3.38e-3)" "unprognostic (5.33e-2)" "unprognostic (3.09e-3)" "unprognostic (1.15e-2)" "unprognostic (7.46e-2)" "unprognostic (4.68e-2)" "unprognostic (5.19e-2)" "unprognostic (1.47e-1)" "unprognostic (2.86e-1)" "unprognostic (5.48e-2)" "unprognostic (4.99e-2)" "unprognostic (2.82e-1)" "unprognostic (6.48e-3)" "unprognostic (1.72e-1)" "unprognostic (8.72e-2)" "unprognostic (1.35e-1)" "unprognostic (1.49e-1)" "unprognostic (8.07e-2)" CD84 "hCD84, mCD84, SLAMF5" ENSG00000066294 "CD84 molecule" Q9UIB8 1 160541095-160579516 "CD markers, Predicted membrane proteins" "Adaptive immunity, Autophagy, Cell adhesion, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 22.6" "Cell type enhanced" "Detected in some" "cDC: 74.1;Hofbauer cells: 91.4;Kupffer cells: 361.8;Macrophages: 165.7;Mast cells: 209.6;Megakaryocyte progenitors: 135.3;Megakaryocyte-Erythroid progenitors: 95.8;Megakaryocytes: 55.6;Microglia: 180.1;Monocyte progenitors: 74.3;monocytes: 68.6;Platelets: 178.7;T-cells: 72.3" "Group enriched" "Detected in some" 45 "central nervous system macrophage: 226.4;leukocyte: 62.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 61 "Leukemia: 11.4;lymphoma: 8.2" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Liver - Kupffer cells, Minor Salivary Gland - Macrophages, Skeletal muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063316, HPA068020, HPA070502" Enhanced Enhanced "Vesicles,Plasma membrane" NA NA 3400000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 1 "Plasma membrane" Vesicles "HPA063316: , HPA068020: , HPA070502: " "unprognostic (4.21e-2)" "unprognostic (2.15e-2)" "unprognostic (4.87e-1)" "unprognostic (2.31e-1)" "unprognostic (1.94e-1)" "unprognostic (2.85e-1)" "unprognostic (1.48e-1)" "unprognostic (8.10e-2)" "unprognostic (2.40e-2)" "unprognostic (9.86e-2)" "unprognostic (2.09e-2)" "unprognostic (1.97e-1)" "unprognostic (1.23e-1)" "unprognostic (6.70e-2)" "unprognostic (2.64e-3)" "unprognostic (1.61e-2)" "unprognostic (9.69e-2)" "unprognostic (7.25e-2)" "unprognostic (7.67e-2)" "unprognostic (3.15e-1)" "unprognostic (6.20e-2)" "unprognostic (4.36e-2)" "unprognostic (2.79e-1)" "unprognostic (5.92e-2)" "unprognostic (4.61e-2)" "unprognostic (2.80e-1)" "unprognostic (1.35e-1)" "unprognostic (1.93e-2)" "unprognostic (1.90e-1)" "unprognostic (2.24e-1)" CD86 "B7-2, B7.2, CD28LG2" ENSG00000114013 "CD86 molecule" P42081 3 122055362-122121139 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity" "Host cell receptor for virus entry, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 32.5" "Group enriched" "Detected in some" 4 "cDC: 462.0;Hofbauer cells: 272.7;Kupffer cells: 260.3;Macrophages: 338.1;Microglia: 365.5;monocytes: 296.9" "Cell type enriched" "Detected in some" 8 "central nervous system macrophage: 472.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "classical monocyte: 80.1;intermediate monocyte: 79.2;memory B-cell: 41.1;myeloid DC: 79.0;naive B-cell: 28.7;non-classical monocyte: 85.6" "Group enriched" "Detected in many" 18 "B-cells: 41.1;dendritic cells: 79.0;monocytes: 85.6" "Cancer enriched" "Detected in some" 6 "lymphoma: 54.5" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Spleen - Macrophages, Stomach - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004319, HPA026802" Approved Supported "Plasma membrane,Centriolar satellite" NA NA 130000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 82: Dendritic cells - Antigen presentation" 3 "Plasma membrane" "Centriolar satellite" "CAB004319: , HPA026802: " "unprognostic (1.96e-1)" "unprognostic (1.97e-1)" "unprognostic (3.93e-1)" "unprognostic (6.14e-2)" "unprognostic (2.12e-1)" "unprognostic (1.99e-1)" "unprognostic (1.55e-1)" "unprognostic (2.78e-1)" "unprognostic (2.07e-1)" "unprognostic (1.57e-1)" "unprognostic (5.50e-2)" "unprognostic (3.54e-1)" "unprognostic (1.10e-1)" "unprognostic (1.49e-2)" "unprognostic (2.22e-1)" "unprognostic (2.98e-2)" "unprognostic (4.94e-3)" "unprognostic (1.01e-1)" "unprognostic (1.75e-1)" "unprognostic (8.71e-2)" "unprognostic (3.25e-1)" "unprognostic (8.71e-2)" "unprognostic (1.02e-3)" "unprognostic (3.57e-1)" "unprognostic (7.46e-2)" "unprognostic (4.25e-2)" "unprognostic (1.27e-3)" "unprognostic (1.59e-1)" "unprognostic (1.03e-2)" "unprognostic (7.84e-2)" "unprognostic (2.94e-1)" CD8A CD8 ENSG00000153563 "CD8a molecule" P01732 2 86784610-86808396 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "lymphoid tissue: 216.0" "Cell type enriched" "Detected in many" 6 "T-cells: 249.0" "Cell type enriched" "Detected in many" 9 "leukocyte: 170.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 14 "MAIT T-cell: 227.9;memory CD8 T-cell: 509.4;naive CD8 T-cell: 461.5" "Lineage enriched" "Detected in many" 19 "T-cells: 509.4" "Group enriched" "Detected in some" 9 "Leukemia: 4.0;lymphoma: 5.1" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Minor Salivary Gland - T-cells, Pancreas - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Skin - T-cells, Stomach - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB000012, HPA037756, CAB075722" Enhanced Supported "Plasma membrane" "Intracellular and membrane" Immunity NA NA 72000 "Cluster 11: T-cells - Unknown function" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 6 "Plasma membrane" "CAB000012: , CAB075722: , HPA037756: " "unprognostic (5.62e-2)" "unprognostic (2.24e-3)" "unprognostic (8.45e-2)" "unprognostic (1.66e-2)" "unprognostic (1.05e-1)" "unprognostic (6.79e-2)" "unprognostic (2.99e-2)" "unprognostic (2.63e-1)" "unprognostic (1.42e-3)" "unprognostic (2.91e-1)" "unprognostic (5.56e-2)" "unprognostic (1.13e-1)" "unprognostic (1.28e-3)" "unprognostic (1.73e-3)" "unprognostic (3.28e-3)" "unprognostic (9.10e-3)" "unprognostic (2.97e-1)" "unprognostic (1.39e-1)" "unprognostic (2.16e-1)" "unprognostic (4.58e-2)" "unprognostic (8.39e-2)" "unprognostic (1.74e-2)" "unprognostic (2.48e-1)" "unprognostic (2.87e-1)" "unprognostic (1.09e-2)" "unprognostic (1.50e-1)" "unprognostic (7.09e-3)" "unprognostic (1.32e-1)" "unprognostic (4.00e-2)" "unprognostic (4.95e-2)" "unprognostic (2.65e-1)" CD8B CD8B1 ENSG00000172116 "CD8b molecule" P10966 2 86815339-86861924 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "lymphoid tissue: 427.3" "Group enriched" "Detected in some" 9 "Endometrial secretory cells: 46.3;T-cells: 153.6" "Cell type enriched" "Detected in some" 14 "leukocyte: 126.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 10 "memory CD8 T-cell: 602.5;naive CD8 T-cell: 1058.1" "Lineage enriched" "Detected in all" 25 "T-cells: 1058.1" "Group enriched" "Detected in some" 9 "Leukemia: 8.7;Myeloma: 33.2" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Minor Salivary Gland - T-cells, Pancreas - T-cells, Pituitary gland - Corticotropes, Prostate - T-cells, Skin - T-cells, Spleen - T-cells, Stomach - T-cells, Thyroid gland - T-cells" "CAB004353, HPA029164" Enhanced Supported "Plasma membrane" "Intracellular and membrane" Immunity NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 80: Thymus - Adaptive immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" "Plasma membrane" "CAB004353: , HPA029164: " "unprognostic (5.53e-3)" "unprognostic (1.52e-3)" "unprognostic (6.39e-2)" "unprognostic (1.32e-3)" "unprognostic (1.51e-1)" "unprognostic (1.76e-1)" "potential prognostic unfavorable (2.85e-4)" "unprognostic (1.16e-1)" "unprognostic (1.03e-3)" "unprognostic (4.71e-2)" "unprognostic (1.78e-1)" "unprognostic (1.27e-2)" "unprognostic (4.54e-3)" "unprognostic (9.97e-2)" "unprognostic (1.79e-2)" "unprognostic (5.63e-2)" "unprognostic (2.43e-1)" "unprognostic (2.09e-1)" "unprognostic (1.31e-1)" "unprognostic (1.21e-1)" "unprognostic (7.60e-2)" "unprognostic (7.58e-2)" "unprognostic (4.21e-1)" "unprognostic (1.43e-2)" "unprognostic (1.27e-2)" "unprognostic (6.30e-3)" "unprognostic (1.21e-1)" "unprognostic (2.80e-2)" "unprognostic (6.73e-2)" "unprognostic (2.73e-1)" CD8B2 CD8BP ENSG00000254126 "CD8b2 molecule" A6NJW9 2 106487364-106544297 "Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 6.9" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 2.7;Epididymal clear cells: 2.0;Gastric chief cells: 1.1;Gonadotrophs: 6.4;Mesothelial cells: 1.6;Pancreatic islet cells: 1.2;Pituitary stem cells: 1.1;Retinal ganglion cells: 3.9;Submucosal glandular cells: 1.6" "Group enriched" "Detected in some" 6 "endothelial cell: 23.5;vascular associated smooth muscle cell: 6.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 9 "memory CD8 T-cell: 18.8;naive CD8 T-cell: 30.8" "Lineage enriched" "Detected in many" 14 "T-cells: 30.8" "Group enriched" "Detected in some" 12 "breast cancer: 7.7;Myeloma: 18.9" "Pituitary gland - Gonadotropes" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 104: Brain endothelial cells - Blood brain barrier" "unprognostic (1.02e-2)" "unprognostic (3.89e-2)" "unprognostic (5.44e-3)" "potential prognostic favorable (6.24e-4)" "unprognostic (4.07e-3)" "unprognostic (7.20e-2)" "unprognostic (3.42e-1)" "unprognostic (1.23e-1)" "unprognostic (2.20e-1)" "unprognostic (4.37e-1)" CD9 "BA2, MIC3, MRP-1, P24, TSPAN29" ENSG00000010278 "CD9 molecule" P21926 12 6199715-6238271 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Fertilization" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 6751.8;Esophageal basal cells: 1957.6;Esophageal suprabasal cells: 3292.3;Respiratory ionocytes: 2532.4;Respiratory secretory cells: 1893.0" "Cell type enhanced" "Detected in many" "oligodendrocyte: 263.5;pericyte: 336.9;vascular associated smooth muscle cell: 199.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 26 "basophil: 1961.8;eosinophil: 1159.2" "Lineage enriched" "Detected in all" 32 "granulocytes: 1961.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB002490 Supported Supported "Plasma membrane" "Intracellular and membrane" "Cell adhesion" NA NA 4200000 "Cluster 41: Basophils - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 20 "Plasma membrane" "CAB002490: " "unprognostic (2.47e-1)" "unprognostic (1.03e-1)" "unprognostic (5.66e-2)" "unprognostic (7.09e-2)" "unprognostic (1.31e-3)" "unprognostic (1.39e-1)" "unprognostic (2.40e-1)" "potential prognostic unfavorable (4.96e-4)" "unprognostic (5.92e-2)" "unprognostic (1.15e-1)" "validated prognostic favorable (1.87e-6)" "validated prognostic favorable (3.24e-5)" "unprognostic (1.34e-1)" "unprognostic (7.21e-2)" "unprognostic (3.13e-2)" "unprognostic (8.25e-2)" "unprognostic (3.86e-2)" "potential prognostic favorable (5.09e-4)" "unprognostic (4.27e-1)" "unprognostic (2.59e-2)" "unprognostic (3.02e-2)" "potential prognostic unfavorable (1.07e-4)" "unprognostic (4.92e-2)" "unprognostic (1.09e-1)" "unprognostic (1.36e-1)" "unprognostic (2.43e-1)" "unprognostic (1.93e-1)" "unprognostic (3.40e-2)" "unprognostic (2.18e-1)" "unprognostic (5.90e-3)" "unprognostic (1.05e-1)" CD93 "C1qR(P), C1QR1, C1qRP, CDw93, dJ737E23.1, ECSM3, MXRA4" ENSG00000125810 "CD93 molecule" Q9NPY3 20 23079360-23086324 "CD markers, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 129.3" "Cell type enhanced" "Detected in some" "cDC: 53.2;Kupffer cells: 153.7;Macrophages: 99.3;Monocyte progenitors: 44.1;monocytes: 260.9;Neutrophil progenitors: 132.5;Neutrophils: 207.5;Vascular endothelial cells: 307.0" "Group enriched" "Detected in some" 21 "central nervous system macrophage: 10.9;endothelial cell: 34.4;leukocyte: 9.8;vascular associated smooth muscle cell: 15.1" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 65.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 15 "classical monocyte: 25.8;intermediate monocyte: 16.8;myeloid DC: 9.1;neutrophil: 27.8;non-classical monocyte: 7.5" "Group enriched" "Detected in many" 41 "dendritic cells: 9.1;granulocytes: 27.8;monocytes: 25.8" "Cancer enhanced" "Detected in some" "Leukemia: 17.2;lymphoma: 6.8" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Lung - Endothelial cells, Minor Salivary Gland - Endothelial cells, Pituitary gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009300, HPA012368" Enhanced Approved "Vesicles,Plasma membrane" NA NA 100000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 12: Non-specific - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 9 "Vesicles, Plasma membrane" "HPA009300: , HPA012368: " "unprognostic (7.45e-2)" "unprognostic (2.24e-1)" "unprognostic (5.33e-2)" "unprognostic (1.01e-1)" "unprognostic (1.02e-1)" "unprognostic (4.14e-2)" "unprognostic (1.31e-1)" "unprognostic (1.54e-1)" "unprognostic (8.87e-2)" "unprognostic (4.81e-2)" "potential prognostic favorable (3.00e-6)" "unprognostic (1.42e-3)" "unprognostic (5.89e-3)" "unprognostic (8.97e-2)" "unprognostic (1.79e-1)" "unprognostic (7.47e-2)" "unprognostic (2.51e-2)" "unprognostic (1.19e-2)" "unprognostic (2.64e-2)" "unprognostic (2.62e-2)" "unprognostic (6.68e-3)" "unprognostic (2.25e-1)" "unprognostic (1.00e-1)" "unprognostic (1.09e-1)" "unprognostic (4.47e-2)" "unprognostic (8.62e-2)" "unprognostic (7.62e-2)" "unprognostic (1.30e-3)" "unprognostic (1.83e-1)" "unprognostic (1.68e-2)" "unprognostic (4.21e-1)" CD96 TACTILE ENSG00000153283 "CD96 molecule" P40200 3 111292719-111665750 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 57.5" "Cell type enhanced" "Detected in many" "Adipocytes: 232.4;B-cells: 159.3;Innate lymphoid cells: 734.9;NK-cells: 656.5;Papillary tip epithelial cells: 176.2;Retinal pigment epithelial cells: 127.9;T-cells: 830.2;Thymocytes: 582.7;Urothelial cells: 299.4" "Cell type enriched" "Detected in many" 25 "leukocyte: 573.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 74.0;MAIT T-cell: 117.3;memory CD4 T-cell: 67.1;memory CD8 T-cell: 85.2;naive CD4 T-cell: 68.8;naive CD8 T-cell: 81.9;NK-cell: 79.7;T-reg: 47.4" "Group enriched" "Detected in many" 5 "NK-cells: 79.7;T-cells: 117.3" "Cancer enhanced" "Detected in many" "Leukemia: 31.3;skin cancer: 14.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Minor Salivary Gland - T-cells, Pancreas - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Skin - T-cells, Stomach - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA066754 Enhanced NA NA 55000 "Cluster 24: Non-specific - Transcription" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 6: Non-specific - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" "HPA066754: " "unprognostic (4.56e-2)" "unprognostic (2.31e-3)" "unprognostic (5.10e-3)" "potential prognostic favorable (7.56e-4)" "unprognostic (1.36e-1)" "unprognostic (2.38e-1)" "unprognostic (2.95e-1)" "unprognostic (1.12e-2)" "unprognostic (1.10e-1)" "unprognostic (1.30e-1)" "unprognostic (8.63e-2)" "unprognostic (1.84e-1)" "unprognostic (1.12e-2)" "unprognostic (1.54e-2)" "unprognostic (2.56e-1)" "unprognostic (2.65e-1)" "unprognostic (5.44e-2)" "unprognostic (3.57e-2)" "unprognostic (4.46e-2)" "unprognostic (2.33e-2)" "unprognostic (1.36e-1)" "unprognostic (2.22e-1)" "unprognostic (2.05e-2)" "unprognostic (1.03e-1)" "unprognostic (2.13e-1)" "unprognostic (7.71e-2)" "unprognostic (5.32e-2)" "unprognostic (5.98e-2)" "unprognostic (1.73e-1)" CD99 MIC2 ENSG00000002586 "CD99 molecule (Xg blood group)" P14209 X 2691187-2741309 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 1032.0;Esophageal apical cells: 1322.4;Hofbauer cells: 1447.9;Melanocytes: 777.5;Pancreatic islet cells: 1384.3;Platelets: 1729.8;Thymocytes: 874.0" "Cell type enhanced" "Detected in some" "ependymal cell: 6.5;leukocyte: 5.7;pericyte: 7.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Fibroblasts_1, Skin - Fibroblasts_2" "Low region specificity" "Detected in all" "CAB000020, HPA035304" Supported Approved "Golgi apparatus" NA NA 64000000 "Cluster 13: Non-specific - Mitochondria" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 108: Fibroblasts - ECM organization" 3 "Golgi apparatus" "CAB000020: , HPA035304: " "unprognostic (3.10e-1)" "unprognostic (1.84e-2)" "unprognostic (3.37e-2)" "unprognostic (1.36e-1)" "unprognostic (3.61e-2)" "unprognostic (5.06e-2)" "unprognostic (5.03e-2)" "unprognostic (4.27e-2)" "unprognostic (4.04e-2)" "unprognostic (9.21e-2)" "unprognostic (1.94e-1)" "unprognostic (4.79e-2)" "unprognostic (1.76e-3)" "validated prognostic unfavorable (2.05e-4)" "validated prognostic unfavorable (3.63e-4)" "unprognostic (1.25e-1)" "unprognostic (3.44e-2)" "unprognostic (4.17e-1)" "unprognostic (3.57e-1)" "unprognostic (3.74e-2)" "unprognostic (1.74e-2)" "unprognostic (1.61e-1)" "unprognostic (2.67e-1)" "unprognostic (4.33e-2)" "unprognostic (4.23e-2)" "unprognostic (5.65e-3)" "unprognostic (8.43e-2)" "unprognostic (2.07e-2)" "unprognostic (1.60e-1)" CD99L2 "CD99B, MIC2L1" ENSG00000102181 "CD99 molecule like 2" Q8TCZ2 X 150766336-150898816 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 170.4" "Cell type enhanced" "Detected in many" "Myonuclei: 144.9;Thymic myoid cells: 126.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Minor Salivary Gland - Endothelial cells, Skin - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038782, HPA038783, HPA061400" Enhanced Approved "Plasma membrane" "Secreted in other tissues" "Cell adhesion" NA NA 1000000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 11 "Plasma membrane" "HPA038782: , HPA038783: , HPA061400: " "unprognostic (4.02e-2)" "potential prognostic unfavorable (8.55e-4)" "unprognostic (2.62e-2)" "unprognostic (1.23e-1)" "unprognostic (6.84e-2)" "unprognostic (1.01e-1)" "unprognostic (3.26e-1)" "unprognostic (3.98e-2)" "unprognostic (1.08e-1)" "unprognostic (2.04e-1)" "potential prognostic favorable (2.38e-4)" "unprognostic (2.38e-1)" "unprognostic (1.68e-1)" "unprognostic (4.87e-2)" "unprognostic (1.88e-1)" "unprognostic (2.93e-3)" "unprognostic (1.45e-1)" "unprognostic (1.97e-1)" "unprognostic (3.67e-1)" "unprognostic (2.98e-1)" "unprognostic (9.69e-2)" "potential prognostic favorable (6.65e-5)" "unprognostic (2.68e-2)" "unprognostic (3.63e-2)" "unprognostic (8.17e-3)" "unprognostic (9.92e-2)" "unprognostic (1.57e-1)" "unprognostic (9.78e-2)" "unprognostic (4.83e-2)" "unprognostic (1.00e-1)" "unprognostic (1.57e-1)" CDA CDD ENSG00000158825 "Cytidine deaminase" P32320 1 20589086-20618903 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 182.8;esophagus: 107.9;liver: 80.9" "Cell type enhanced" "Detected in many" "Colonocytes: 321.5;Enterocytes: 158.7;Esophageal apical cells: 1689.0;Esophageal suprabasal cells: 458.2;Hepatocytes: 182.3;Neutrophil progenitors: 635.5;Neutrophils: 882.5" "Cell type enriched" "Detected in some" 8 "endothelial cell: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 1240.3" "Lineage enriched" "Detected in many" 6 "granulocytes: 1240.3" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 157.8" "Lung - Neutrophils_2, Spleen - Neutrophils_2, Testis - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA064202 Enhanced Approved Nucleoplasm NA NA 1400000 "Cluster 21: Neutrophils - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 47: Endothelial cells - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 19 Nucleoplasm "HPA064202: " "unprognostic (9.46e-3)" "unprognostic (7.62e-2)" "unprognostic (8.85e-2)" "potential prognostic unfavorable (6.44e-4)" "unprognostic (9.88e-2)" "unprognostic (1.80e-1)" "unprognostic (2.23e-2)" "unprognostic (1.66e-2)" "unprognostic (5.37e-3)" "unprognostic (5.73e-2)" "unprognostic (1.84e-2)" "unprognostic (1.17e-2)" "unprognostic (5.27e-2)" "unprognostic (5.80e-2)" "unprognostic (2.15e-2)" "unprognostic (5.62e-3)" "unprognostic (9.21e-3)" "unprognostic (1.67e-2)" "unprognostic (3.14e-2)" "unprognostic (2.62e-2)" "unprognostic (2.66e-1)" "validated prognostic unfavorable (1.19e-5)" "validated prognostic unfavorable (5.36e-4)" "unprognostic (5.33e-2)" "unprognostic (1.47e-1)" "unprognostic (9.35e-3)" "unprognostic (3.12e-1)" "unprognostic (2.52e-3)" "unprognostic (8.82e-2)" "unprognostic (2.01e-1)" "unprognostic (3.13e-2)" CDADC1 NYD-SP15 ENSG00000102543 "Cytidine and dCMP deaminase domain containing 1" Q9BWV3 13 49247925-49293485 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 232.3;Hematopoietic stem cells: 208.6;Neutrophil progenitors: 483.9;Neutrophils: 450.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 9.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 9.9" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047615, HPA058314" Uncertain Approved Nucleoplasm No No "Cluster 42: Non-specific - Vesicular transport" "Cluster 76: Non-specific - Metabolism" "Cluster 38: Sub-cortical - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" Nucleoplasm "HPA047615: , HPA058314: " "unprognostic (2.72e-1)" "unprognostic (1.07e-1)" "unprognostic (4.07e-2)" "unprognostic (5.42e-2)" "unprognostic (3.01e-1)" "unprognostic (1.82e-1)" "unprognostic (1.26e-1)" "unprognostic (1.52e-1)" "unprognostic (1.50e-1)" "unprognostic (2.28e-1)" "potential prognostic favorable (1.27e-9)" "unprognostic (1.46e-3)" "potential prognostic favorable (2.04e-4)" "unprognostic (9.82e-3)" "unprognostic (2.57e-1)" "potential prognostic favorable (5.02e-4)" "unprognostic (9.64e-2)" "unprognostic (1.18e-1)" "unprognostic (3.12e-2)" "unprognostic (1.61e-2)" "unprognostic (5.94e-3)" "unprognostic (1.87e-2)" "unprognostic (9.06e-3)" "unprognostic (1.30e-1)" "unprognostic (6.64e-2)" "unprognostic (1.54e-1)" "unprognostic (8.81e-3)" "unprognostic (1.11e-2)" "unprognostic (1.83e-1)" "unprognostic (3.49e-3)" "unprognostic (3.65e-2)" CDAN1 "CDA-I, CDAI" ENSG00000140326 "Codanin 1" Q8IWY9 15 42723544-42737128 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Congenital dyserythropoietic anemia, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039404, HPA040787" Supported Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 75: Ovary - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 8 Cytosol "Plasma membrane" "HPA039404: , HPA040787: " "unprognostic (1.39e-3)" "unprognostic (1.93e-2)" "unprognostic (2.75e-1)" "unprognostic (8.41e-2)" "unprognostic (1.08e-1)" "unprognostic (6.95e-2)" "unprognostic (8.69e-2)" "unprognostic (2.88e-3)" "unprognostic (1.26e-1)" "unprognostic (1.67e-2)" "unprognostic (3.17e-3)" "unprognostic (2.31e-2)" "unprognostic (5.11e-1)" "potential prognostic unfavorable (2.11e-4)" "unprognostic (2.56e-2)" "unprognostic (8.26e-2)" "unprognostic (5.60e-3)" "unprognostic (1.41e-1)" "unprognostic (1.86e-2)" "unprognostic (5.80e-2)" "unprognostic (1.37e-1)" "unprognostic (1.17e-1)" "unprognostic (1.78e-2)" "unprognostic (4.58e-1)" "unprognostic (7.47e-3)" "unprognostic (5.88e-2)" "unprognostic (1.20e-1)" "unprognostic (1.51e-1)" "unprognostic (3.58e-1)" "unprognostic (2.75e-1)" "unprognostic (2.46e-1)" CDC123 "C10orf7, D123" ENSG00000151465 "Cell division cycle 123" O75794 10 12195965-12250589 "Essential proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 605.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037830, HPA057540" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 14: Neurons - Synaptic function" "Cluster 52: Non-specific - Mitochondria" "Cluster 24: Neutrophils - Innate immunity signal integration" 17 "Nucleoplasm, Golgi apparatus" Cytosol "HPA037830: , HPA057540: " "unprognostic (9.54e-2)" "unprognostic (2.71e-3)" "unprognostic (3.76e-1)" "unprognostic (3.74e-2)" "unprognostic (1.59e-1)" "unprognostic (2.72e-2)" "unprognostic (8.04e-2)" "potential prognostic favorable (1.59e-6)" "unprognostic (3.77e-2)" "unprognostic (4.40e-3)" "unprognostic (5.04e-3)" "unprognostic (2.22e-1)" "unprognostic (3.32e-3)" "validated prognostic unfavorable (1.24e-6)" "validated prognostic unfavorable (1.94e-4)" "unprognostic (9.87e-3)" "unprognostic (6.31e-2)" "unprognostic (4.39e-2)" "unprognostic (1.56e-1)" "unprognostic (4.23e-1)" "unprognostic (6.37e-2)" "unprognostic (8.18e-2)" "unprognostic (1.06e-2)" "unprognostic (1.40e-1)" "unprognostic (1.64e-1)" "unprognostic (3.39e-1)" "unprognostic (2.26e-1)" "unprognostic (1.82e-2)" "unprognostic (2.63e-1)" "unprognostic (1.75e-1)" "unprognostic (2.57e-2)" CDC14A "cdc14, Cdc14A1, Cdc14A2, DFNB105, DFNB32" ENSG00000079335 "Cell division cycle 14A" Q9UNH5 1 100345001-100520277 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Hearing" "Hydrolase, Protein phosphatase" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 24.8" "Cell type enhanced" "Detected in many" "Innate lymphoid cells: 730.7;Podocytes: 1893.4;T-cells: 544.4" "Cell type enhanced" "Detected in many" "astrocyte: 217.9;endothelial cell: 254.0;leukocyte: 300.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 18.9" "Kidney - Podocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023783 Approved Approved "Nucleoplasm,Endoplasmic reticulum,Cytosol" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 9: T-cells - Adaptive immunity: Regulation" 12 "Nucleoplasm, Endoplasmic reticulum" Cytosol "HPA023783: " "unprognostic (2.68e-1)" "unprognostic (9.54e-2)" "unprognostic (4.80e-1)" "unprognostic (1.61e-1)" "unprognostic (4.57e-2)" "unprognostic (4.39e-3)" "unprognostic (2.78e-2)" "unprognostic (1.79e-1)" "unprognostic (1.02e-1)" "unprognostic (4.64e-3)" "validated prognostic favorable (1.36e-6)" "validated prognostic favorable (3.75e-4)" "unprognostic (3.53e-2)" "unprognostic (4.13e-1)" "unprognostic (4.25e-2)" "unprognostic (4.58e-2)" "unprognostic (8.32e-2)" "unprognostic (2.72e-2)" "unprognostic (3.79e-1)" "unprognostic (1.90e-2)" "unprognostic (1.56e-1)" "unprognostic (1.58e-2)" "unprognostic (2.75e-1)" "unprognostic (3.93e-3)" "unprognostic (2.57e-2)" "unprognostic (2.33e-1)" "unprognostic (9.33e-2)" "unprognostic (1.87e-1)" "unprognostic (5.86e-2)" "unprognostic (1.46e-1)" CDC14B "Cdc14B1, Cdc14B2, CDC14B3, hCDC14B" ENSG00000081377 "Cell division cycle 14B" O60729 9 96490241-96619843 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 402.2;Pituicytes/FSCs: 332.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 10.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 10.9" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" HPA064747 Supported "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 61: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 12 Nucleoplasm "Cell Junctions, Cytosol" "HPA064747: " "unprognostic (5.37e-2)" "unprognostic (6.83e-2)" "unprognostic (2.31e-1)" "unprognostic (7.83e-2)" "unprognostic (3.07e-1)" "unprognostic (3.07e-2)" "validated prognostic favorable (1.92e-9)" "validated prognostic favorable (1.80e-4)" "unprognostic (1.56e-1)" "unprognostic (1.16e-2)" "unprognostic (4.86e-2)" "unprognostic (1.82e-1)" "unprognostic (5.05e-3)" "unprognostic (5.72e-2)" "unprognostic (2.14e-1)" "unprognostic (1.00e-1)" "unprognostic (1.96e-2)" "unprognostic (3.95e-2)" CDC14C "CDC14B2, CDC14Bretro, CDC14CP, MGC26484" ENSG00000218305 "Cell division cycle 14C" A4D256 7 48924547-48927454 "Enzymes, Essential proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "retina: 4.1;testis: 7.0" "Cell type enriched" "Detected in some" 4 "Late primary spermatocytes: 46.7" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" NA NA "Cluster 47: Testis - Mixed function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 56: Non-specific - Sensory perception" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" "unprognostic (5.57e-3)" "unprognostic (3.33e-3)" "unprognostic (2.24e-2)" CDC16 "ANAPC6, APC6, CUT9" ENSG00000130177 "Cell division cycle 16" Q13042 13 114234887-114272723 "Cancer-related genes, Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042826 Approved NA NA 6400 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 21: Non-specific - Metabolism" "Cluster 19: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 83 "HPA042826: " "unprognostic (3.22e-2)" "unprognostic (1.02e-1)" "unprognostic (4.70e-1)" "unprognostic (1.79e-2)" "unprognostic (1.95e-1)" "unprognostic (7.85e-2)" "unprognostic (6.48e-2)" "unprognostic (1.77e-1)" "unprognostic (2.77e-2)" "unprognostic (6.46e-2)" "unprognostic (5.98e-2)" "unprognostic (1.39e-2)" "potential prognostic favorable (1.88e-4)" "potential prognostic unfavorable (4.48e-4)" "unprognostic (4.29e-2)" "unprognostic (2.86e-2)" "unprognostic (2.25e-2)" "unprognostic (8.19e-2)" "unprognostic (1.11e-1)" "unprognostic (1.57e-1)" "unprognostic (2.07e-1)" "unprognostic (1.18e-1)" "unprognostic (2.81e-3)" "unprognostic (4.06e-1)" "unprognostic (1.08e-1)" "unprognostic (1.09e-1)" "unprognostic (1.57e-1)" "unprognostic (9.58e-2)" "unprognostic (1.09e-1)" "unprognostic (5.48e-2)" "unprognostic (2.87e-1)" CDC20 "CDC20A, p55CDC" ENSG00000117399 "Cell division cycle 20" Q12834 1 43358981-43363203 "Cancer-related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Differentiation, Mitosis, Neurogenesis, Ubl conjugation pathway" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 50.8;lymphoid tissue: 49.0;testis: 46.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 77.1;Early spermatids: 120.5;Enteric transient amplifying cells: 103.3;Erythrocyte progenitors: 117.1;Esophageal basal cells: 131.2;Extravillous trophoblasts: 148.4;Gastric progenitor cells: 56.4;Hofbauer cells: 51.6;Late primary spermatocytes: 259.0;Megakaryocyte progenitors: 62.4;Migrating cytotrophoblasts: 119.5;Monocyte progenitors: 79.5" "Cell type enhanced" "Detected in single" "oligodendrocyte: 2.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 7 "memory B-cell: 4.2;memory CD4 T-cell: 3.2;memory CD8 T-cell: 3.5;NK-cell: 9.6;T-reg: 11.6" "Group enriched" "Detected in many" 9 "B-cells: 4.2;NK-cells: 9.6;T-cells: 11.6" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB004525, HPA045842, HPA055288" Enhanced Approved Nucleoplasm,Cytosol Yes Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 11: White matter - Signal transduction" "Cluster 37: Non-specific - mRNA processing" "Cluster 27: Non-specific - Cell proliferation" 123 "Nucleoplasm, Cytosol" "CAB004525: , HPA045842: , HPA055288: " "unprognostic (1.23e-3)" "unprognostic (9.83e-3)" "unprognostic (1.12e-1)" "unprognostic (2.93e-2)" "unprognostic (5.30e-3)" "unprognostic (7.61e-2)" "unprognostic (2.61e-1)" "unprognostic (8.32e-2)" "unprognostic (1.65e-1)" "potential prognostic unfavorable (3.74e-4)" "validated prognostic unfavorable (7.80e-14)" "validated prognostic unfavorable (2.16e-6)" "potential prognostic unfavorable (7.85e-11)" "validated prognostic unfavorable (1.66e-8)" "validated prognostic unfavorable (9.25e-9)" "validated prognostic unfavorable (2.76e-4)" "validated prognostic unfavorable (5.85e-5)" "unprognostic (2.32e-1)" "unprognostic (2.54e-1)" "unprognostic (1.24e-1)" "potential prognostic favorable (8.10e-4)" "potential prognostic unfavorable (7.75e-5)" "unprognostic (1.01e-1)" "unprognostic (1.24e-1)" "unprognostic (7.63e-2)" "unprognostic (2.38e-1)" "unprognostic (3.21e-3)" "unprognostic (3.77e-2)" "unprognostic (3.51e-1)" "unprognostic (1.36e-1)" "unprognostic (7.95e-2)" CDC20B FLJ37927 ENSG00000164287 "Cell division cycle 20B" Q86Y33 5 55112971-55173177 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 1.9;kidney: 1.0;testis: 2.4" "Cell type enriched" "Detected in many" 55 "Respiratory deuterosomal cells: 3831.4" "Group enriched" "Detected in some" 13 "choroid plexus epithelial cell: 7.3;ependymal cell: 4.3;fibroblast: 6.5" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 8.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Esophageal cancer: 1.1" "Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA053900 Uncertain NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 59: Leukemia - T-cell receptor" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 11 "HPA053900: " "unprognostic (1.95e-2)" "unprognostic (2.35e-1)" "unprognostic (1.98e-2)" "unprognostic (1.69e-1)" "unprognostic (4.95e-2)" "unprognostic (1.29e-3)" "unprognostic (1.37e-1)" "unprognostic (1.07e-1)" "unprognostic (1.57e-1)" CDC23 "ANAPC8, APC8, CUT23" ENSG00000094880 "Cell division cycle 23" Q9UJX2 5 138187650-138213343 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 82.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039593 Approved NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 152 "HPA039593: " "unprognostic (3.21e-1)" "unprognostic (9.73e-3)" "unprognostic (4.21e-2)" "unprognostic (2.16e-1)" "unprognostic (5.73e-2)" "unprognostic (3.69e-2)" "unprognostic (3.59e-1)" "unprognostic (4.83e-1)" "unprognostic (2.90e-1)" "unprognostic (1.49e-1)" "potential prognostic favorable (6.24e-8)" "unprognostic (6.58e-2)" "unprognostic (1.42e-1)" "potential prognostic unfavorable (6.99e-4)" "unprognostic (3.85e-2)" "unprognostic (1.04e-3)" "unprognostic (3.31e-1)" "unprognostic (1.78e-1)" "unprognostic (1.90e-1)" "unprognostic (2.16e-2)" "unprognostic (7.76e-3)" "unprognostic (1.87e-1)" "unprognostic (1.11e-2)" "unprognostic (1.35e-1)" "unprognostic (1.46e-2)" "unprognostic (1.56e-1)" "unprognostic (2.83e-1)" "unprognostic (1.68e-1)" "unprognostic (1.90e-1)" "unprognostic (2.24e-1)" "unprognostic (1.54e-1)" CDC25A ENSG00000164045 "Cell division cycle 25A" P30304 3 48157146-48188417 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 14.4;lymphoid tissue: 8.2;testis: 12.4" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 20.8;Early primary spermatocytes: 16.4;Early spermatids: 19.5;Erythrocyte progenitors: 32.1;Late primary spermatocytes: 14.5;Late spermatids: 48.1;Megakaryocyte progenitors: 20.4;Monocyte progenitors: 16.0;Neutrophil progenitors: 11.2;Oocytes: 13.8;Undifferentiated spermatogonia: 12.0" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 31.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Lung - Mitotic cells (Lung), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005855, HPA008803" Approved "Nucleoplasm,Golgi apparatus" NA Yes "Cluster 44: Bone marrow - Nuclear processes" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 44 Nucleoplasm "Golgi apparatus" "HPA005855: , HPA008803: " "unprognostic (3.43e-2)" "unprognostic (1.21e-1)" "unprognostic (2.31e-1)" "unprognostic (8.30e-2)" "unprognostic (4.14e-2)" "unprognostic (5.32e-1)" "unprognostic (2.97e-1)" "unprognostic (2.18e-2)" "unprognostic (1.28e-1)" "potential prognostic unfavorable (2.57e-5)" "unprognostic (3.48e-2)" "validated prognostic unfavorable (4.35e-7)" "validated prognostic unfavorable (6.53e-7)" "potential prognostic unfavorable (7.74e-4)" "unprognostic (8.13e-3)" "unprognostic (9.67e-3)" "unprognostic (2.42e-2)" "unprognostic (9.18e-2)" "unprognostic (1.64e-1)" "unprognostic (6.47e-2)" "unprognostic (1.17e-1)" "unprognostic (2.19e-1)" "unprognostic (1.17e-1)" "unprognostic (2.46e-1)" "potential prognostic unfavorable (7.71e-4)" "unprognostic (2.84e-2)" "unprognostic (1.93e-1)" "unprognostic (2.25e-1)" "unprognostic (1.56e-1)" CDC25B ENSG00000101224 "Cell division cycle 25B" P30305 20 3786772-3806121 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 60.6;Brain inhibitory neurons: 63.4;Corticotrophs: 62.1;Retinal ganglion cells: 65.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 4 "B-cells: 7.2;NK-cells: 18.1;T-cells: 28.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038892, HPA038893, HPA075215" Enhanced Uncertain "Vesicles,Mitotic spindle" Yes Yes "Cluster 5: Non-specific - Cell proliferation" "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 27: Non-specific - Cell proliferation" 34 Vesicles "Mitotic spindle" "HPA038892: , HPA038893: , HPA075215: " "unprognostic (4.43e-2)" "unprognostic (4.64e-2)" "unprognostic (2.25e-2)" "unprognostic (1.03e-1)" "unprognostic (9.74e-2)" "unprognostic (1.36e-2)" "unprognostic (1.46e-1)" "unprognostic (9.25e-3)" "unprognostic (1.64e-1)" "unprognostic (1.74e-3)" "potential prognostic unfavorable (3.01e-6)" "unprognostic (4.12e-3)" "unprognostic (6.94e-2)" "validated prognostic unfavorable (1.42e-4)" "validated prognostic unfavorable (4.00e-4)" "unprognostic (3.92e-2)" "unprognostic (7.36e-2)" "potential prognostic unfavorable (4.21e-4)" "unprognostic (5.41e-2)" "unprognostic (2.89e-1)" "unprognostic (1.62e-2)" "unprognostic (9.75e-2)" "unprognostic (2.49e-2)" "unprognostic (6.67e-2)" "unprognostic (1.80e-1)" "unprognostic (6.85e-2)" "unprognostic (7.07e-2)" "unprognostic (7.47e-2)" "unprognostic (3.27e-1)" "unprognostic (3.03e-1)" "unprognostic (9.01e-2)" CDC25C "CDC25, PPP1R60" ENSG00000158402 "Cell division cycle 25C" P30307 5 138285269-138338355 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Host-virus interaction, Mitosis" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.4;lymphoid tissue: 8.3;testis: 16.9" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 72.2;Early spermatids: 91.4;Enteric transient amplifying cells: 37.3;Erythrocyte progenitors: 45.8;Late primary spermatocytes: 92.1;Late spermatids: 63.1;Megakaryocyte progenitors: 34.3;Monocyte progenitors: 58.8;Neutrophil progenitors: 35.7;Oocytes: 50.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB003800, HPA066991" Approved Supported "Nuclear speckles" No Yes "Cluster 39: Testis - Nuclear processes" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Non-specific - Cell proliferation" 55 "Nuclear speckles" "CAB003800: , HPA066991: " "unprognostic (2.46e-2)" "unprognostic (4.14e-2)" "unprognostic (3.47e-1)" "unprognostic (4.24e-3)" "unprognostic (3.25e-3)" "unprognostic (9.47e-2)" "unprognostic (9.35e-2)" "unprognostic (3.82e-2)" "unprognostic (1.09e-1)" "validated prognostic unfavorable (2.57e-8)" "validated prognostic unfavorable (5.09e-6)" "validated prognostic unfavorable (2.26e-7)" "validated prognostic unfavorable (6.28e-8)" "potential prognostic unfavorable (2.38e-5)" "unprognostic (1.91e-3)" "unprognostic (2.64e-3)" "unprognostic (7.14e-2)" "unprognostic (1.42e-1)" "unprognostic (1.31e-1)" "potential prognostic unfavorable (1.95e-4)" "unprognostic (2.88e-3)" "unprognostic (9.00e-2)" "unprognostic (4.01e-2)" "unprognostic (8.14e-2)" "unprognostic (1.10e-1)" "unprognostic (2.33e-2)" "unprognostic (1.93e-1)" "unprognostic (8.08e-3)" CDC26 "ANAPC12, APC12, C9orf17" ENSG00000176386 "Cell division cycle 26" Q8NHZ8 9 113255835-113275572 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 59.4;Neutrophils: 30.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044130 Approved Approved Nucleoplasm NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 76: Non-specific - Metabolism" "Cluster 8: Immune cells - Immune response" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 66 Nucleoplasm "HPA044130: " "unprognostic (9.42e-3)" "unprognostic (9.23e-2)" "unprognostic (3.12e-1)" "unprognostic (2.33e-2)" "unprognostic (1.27e-2)" "unprognostic (3.49e-2)" "unprognostic (2.09e-2)" "unprognostic (3.59e-1)" "unprognostic (3.56e-3)" "unprognostic (5.78e-2)" "potential prognostic favorable (7.57e-6)" "unprognostic (1.04e-2)" "unprognostic (6.01e-2)" "unprognostic (2.40e-3)" "potential prognostic unfavorable (7.96e-4)" "unprognostic (1.61e-2)" "unprognostic (9.83e-2)" "unprognostic (9.40e-2)" "unprognostic (1.42e-1)" "unprognostic (3.61e-2)" "unprognostic (1.26e-1)" "unprognostic (5.75e-2)" "unprognostic (3.23e-1)" "unprognostic (1.51e-1)" "unprognostic (2.25e-2)" "unprognostic (1.01e-1)" "unprognostic (9.55e-2)" "unprognostic (1.38e-1)" "unprognostic (1.23e-1)" "unprognostic (3.53e-1)" "unprognostic (4.90e-2)" CDC27 "ANAPC3, APC3, D0S1430E, D17S978E, NUC2" ENSG00000004897 "Cell division cycle 27" P30260 17 47117703-47189422 "Cancer-related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythrocyte progenitors: 358.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016315, HPA028129, HPA052399, HPA065835" Supported Enhanced Nucleoplasm NA Yes "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 103: Non-specific - Basic cellular processes" 114 Nucleoplasm "CAB016315: , HPA028129: , HPA052399: , HPA065835: " "unprognostic (3.38e-2)" "unprognostic (6.77e-3)" "unprognostic (2.50e-2)" "unprognostic (1.19e-2)" "unprognostic (1.81e-2)" "unprognostic (1.86e-2)" "unprognostic (1.12e-1)" "unprognostic (3.98e-2)" "unprognostic (3.22e-2)" "unprognostic (2.06e-3)" "potential prognostic favorable (3.08e-5)" "unprognostic (3.19e-2)" "unprognostic (6.82e-3)" "potential prognostic unfavorable (1.02e-4)" "unprognostic (2.10e-3)" "unprognostic (1.26e-3)" "unprognostic (6.72e-3)" "unprognostic (6.89e-2)" "unprognostic (2.92e-2)" "unprognostic (7.19e-2)" "potential prognostic unfavorable (1.04e-4)" "validated prognostic unfavorable (8.21e-5)" "validated prognostic unfavorable (4.12e-5)" "unprognostic (8.32e-2)" "unprognostic (1.57e-2)" "unprognostic (2.98e-1)" "unprognostic (1.16e-1)" "unprognostic (1.15e-1)" "unprognostic (1.68e-1)" "unprognostic (1.23e-1)" "unprognostic (4.93e-2)" CDC34 "E2-CDC34, UBC3, UBE2R1" ENSG00000099804 "Cell division cycle 34, ubiqiutin conjugating enzyme" P49427 19 531760-542092 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocytes: 109.2;Late spermatids: 384.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Skin - Keratinocyte (granular), Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002382, CAB005109, CAB047311, HPA074334" Approved Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 24: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 35 "Nucleoplasm, Nuclear speckles" Cytosol "CAB005109: , CAB047311: , HPA002382: , HPA074334: " "unprognostic (3.09e-1)" "unprognostic (4.16e-2)" "unprognostic (2.54e-2)" "unprognostic (2.22e-1)" "unprognostic (5.41e-2)" "unprognostic (3.80e-1)" "unprognostic (2.93e-1)" "unprognostic (1.72e-1)" "unprognostic (2.27e-2)" "unprognostic (3.41e-2)" "unprognostic (6.77e-3)" "unprognostic (6.83e-2)" "unprognostic (1.35e-1)" "potential prognostic unfavorable (1.33e-4)" "unprognostic (5.03e-2)" "unprognostic (5.99e-3)" "unprognostic (7.03e-2)" "unprognostic (1.84e-1)" "unprognostic (1.10e-1)" "unprognostic (1.07e-1)" "unprognostic (1.32e-1)" "unprognostic (6.33e-2)" "unprognostic (7.85e-2)" "unprognostic (1.09e-1)" "unprognostic (1.37e-1)" "unprognostic (2.87e-1)" "unprognostic (2.89e-1)" "unprognostic (1.12e-2)" "unprognostic (5.15e-2)" "unprognostic (1.50e-2)" "unprognostic (1.47e-1)" CDC37 P50CDC37 ENSG00000105401 "Cell division cycle 37, HSP90 cochaperone" Q16543 19 10391133-10420121 "Cancer-related genes, Essential proteins, Predicted intracellular proteins, Transporters" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 623.2;Late spermatids: 404.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003928, CAB004214" Supported Supported Cytosol NA NA 1600000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 24: Non-specific - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 23: Non-specific - Transcription" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 411 Cytosol "CAB004214: , HPA003928: " "unprognostic (4.13e-2)" "unprognostic (2.36e-1)" "unprognostic (7.95e-2)" "unprognostic (3.64e-2)" "unprognostic (2.84e-1)" "unprognostic (6.10e-1)" "unprognostic (9.38e-2)" "unprognostic (1.49e-1)" "unprognostic (2.65e-2)" "unprognostic (2.48e-1)" "potential prognostic favorable (9.84e-5)" "unprognostic (9.97e-3)" "unprognostic (9.30e-2)" "unprognostic (1.42e-1)" "unprognostic (2.79e-1)" "unprognostic (1.10e-3)" "unprognostic (1.10e-2)" "unprognostic (2.36e-1)" "unprognostic (6.81e-2)" "unprognostic (1.14e-2)" "unprognostic (1.14e-1)" "unprognostic (1.07e-1)" "unprognostic (1.23e-1)" "unprognostic (5.90e-2)" "unprognostic (1.04e-1)" "unprognostic (4.11e-1)" "unprognostic (1.72e-1)" "unprognostic (1.11e-3)" "unprognostic (6.17e-2)" "unprognostic (1.02e-1)" "unprognostic (2.27e-2)" CDC37L1 "CDC37B, FLJ20639, HARC" ENSG00000106993 "Cell division cycle 37 like 1, HSP90 cochaperone" Q7L3B6 9 4679559-4708399 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 80.0" "Cell type enhanced" "Detected in all" "Hepatocytes: 183.7;Thymic myoid cells: 262.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021175 Approved Supported Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 14: Neurons - Synaptic function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 27 Cytosol "HPA021175: " "unprognostic (3.70e-2)" "unprognostic (1.80e-2)" "unprognostic (9.85e-2)" "unprognostic (1.72e-2)" "unprognostic (2.64e-2)" "unprognostic (1.23e-2)" "unprognostic (1.17e-1)" "unprognostic (1.53e-1)" "unprognostic (9.40e-2)" "unprognostic (6.27e-2)" "validated prognostic favorable (1.19e-8)" "validated prognostic favorable (5.71e-4)" "unprognostic (3.54e-3)" "unprognostic (7.26e-3)" "potential prognostic favorable (7.38e-4)" "unprognostic (2.94e-2)" "unprognostic (1.77e-2)" "unprognostic (1.06e-1)" "unprognostic (1.67e-1)" "unprognostic (1.69e-1)" "unprognostic (1.80e-1)" "unprognostic (1.36e-1)" "unprognostic (5.65e-2)" "unprognostic (1.90e-2)" "unprognostic (1.04e-1)" "unprognostic (4.91e-1)" "unprognostic (3.70e-1)" "unprognostic (1.87e-1)" "unprognostic (3.24e-1)" "unprognostic (1.56e-1)" "unprognostic (8.10e-2)" CDC40 "EHB3, FLJ10564, PRP17, PRPF17" ENSG00000168438 "Cell division cycle 40" O60508 6 110180141-110254275 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 315.9;Early spermatids: 368.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046620 Supported Nucleoplasm NA NA "Cluster 32: Basophils - Transcription" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 34: Non-specific - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 59 Nucleoplasm "HPA046620: " "unprognostic (1.84e-1)" "potential prognostic unfavorable (1.59e-4)" "unprognostic (3.52e-3)" "unprognostic (9.65e-2)" "unprognostic (9.85e-2)" "unprognostic (1.09e-2)" "unprognostic (1.22e-2)" "unprognostic (8.01e-3)" "unprognostic (1.38e-1)" "unprognostic (2.77e-3)" "potential prognostic favorable (1.73e-6)" "unprognostic (2.74e-3)" "unprognostic (1.84e-1)" "potential prognostic unfavorable (5.63e-4)" "unprognostic (3.58e-1)" "unprognostic (6.57e-2)" "unprognostic (2.91e-1)" "unprognostic (2.25e-1)" "unprognostic (2.04e-2)" "unprognostic (3.14e-2)" "unprognostic (7.81e-3)" "unprognostic (5.36e-2)" "unprognostic (2.93e-2)" "unprognostic (2.00e-1)" "unprognostic (1.45e-3)" "unprognostic (9.71e-2)" "unprognostic (2.79e-1)" "unprognostic (3.15e-1)" "unprognostic (1.26e-1)" "unprognostic (2.47e-1)" "unprognostic (1.03e-1)" CDC42 "CDC42Hs, G25K" ENSG00000070831 "Cell division cycle 42" P60953 1 22052627-22101360 "Disease related genes, Enzymes, Essential proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Differentiation, Neurogenesis" Hydrolase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 90.8;Microglia: 123.1;Oligodendrocytes: 97.3;Other brain neurons: 129.6;Papillary tip epithelial cells: 153.4;Renal collecting duct intercalated cells: 91.4;Renal collecting duct principal cells: 107.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004360, HPA069590" Approved Supported "Microtubules,Cytokinetic bridge" Yes No 2900000 "Cluster 28: Neutrophils - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 98: Neurons - Neurotransmission & signaling" 239 Microtubules "Cytokinetic bridge" "CAB004360: , HPA069590: " "potential prognostic unfavorable (9.26e-4)" "unprognostic (7.91e-2)" "unprognostic (3.60e-2)" "unprognostic (1.05e-2)" "potential prognostic favorable (6.82e-4)" "unprognostic (3.44e-1)" "unprognostic (9.37e-2)" "unprognostic (3.17e-1)" "unprognostic (6.27e-2)" "unprognostic (4.52e-2)" "potential prognostic favorable (1.93e-8)" "unprognostic (1.66e-2)" "unprognostic (3.84e-1)" "validated prognostic unfavorable (1.23e-5)" "validated prognostic unfavorable (3.25e-4)" "unprognostic (1.28e-1)" "unprognostic (1.41e-1)" "unprognostic (1.12e-1)" "unprognostic (2.27e-1)" "unprognostic (2.12e-1)" "unprognostic (2.31e-2)" "unprognostic (9.55e-3)" "unprognostic (9.15e-2)" "unprognostic (3.85e-2)" "unprognostic (2.80e-1)" "unprognostic (6.31e-2)" "unprognostic (4.86e-2)" "unprognostic (1.56e-1)" "unprognostic (1.10e-1)" "unprognostic (1.74e-2)" "unprognostic (9.71e-2)" CDC42BPA "FLJ23347, KIAA0451, MRCK, MRCKA, PK428" ENSG00000143776 "CDC42 binding protein kinase alpha" Q5VT25 1 226989865-227318492 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Prostate - Smooth muscle cells, Skin - Endothelial cells, Spleen - Endothelial cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB070414, HPA071252" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 34: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 22 "Plasma membrane, Cytosol" "CAB070414: , HPA071252: " "unprognostic (2.40e-3)" "unprognostic (8.32e-3)" "unprognostic (4.26e-1)" "unprognostic (2.39e-2)" "unprognostic (1.07e-1)" "unprognostic (7.91e-3)" "unprognostic (2.15e-1)" "unprognostic (4.55e-1)" "unprognostic (1.75e-2)" "unprognostic (2.38e-1)" "validated prognostic favorable (1.24e-6)" "validated prognostic favorable (2.06e-4)" "unprognostic (1.42e-1)" "unprognostic (1.51e-2)" "unprognostic (7.60e-2)" "unprognostic (1.01e-2)" "unprognostic (7.39e-3)" "unprognostic (3.85e-1)" "unprognostic (1.52e-1)" "unprognostic (3.15e-1)" "unprognostic (1.76e-2)" "unprognostic (3.02e-2)" "unprognostic (9.03e-2)" "unprognostic (9.52e-2)" "unprognostic (5.96e-2)" "unprognostic (5.99e-2)" "unprognostic (2.47e-1)" "unprognostic (1.33e-2)" "unprognostic (2.92e-1)" "unprognostic (6.14e-2)" "unprognostic (1.23e-2)" CDC42BPB "KIAA1124, MRCKB" ENSG00000198752 "CDC42 binding protein kinase beta" Q9Y5S2 14 102932380-103057549 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022821 Approved NA NA 21000 "Cluster 74: Non-specific - Signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 25 "HPA022821: " "unprognostic (3.19e-1)" "unprognostic (2.68e-2)" "unprognostic (1.04e-1)" "unprognostic (1.29e-2)" "unprognostic (1.90e-2)" "unprognostic (2.96e-1)" "unprognostic (2.94e-2)" "unprognostic (6.51e-2)" "unprognostic (2.38e-1)" "unprognostic (4.07e-3)" "potential prognostic favorable (2.39e-6)" "unprognostic (1.15e-3)" "unprognostic (3.60e-2)" "unprognostic (2.18e-2)" "unprognostic (2.19e-1)" "unprognostic (1.32e-3)" "unprognostic (2.12e-1)" "potential prognostic unfavorable (1.98e-4)" "unprognostic (2.14e-1)" "unprognostic (6.06e-2)" "unprognostic (2.34e-2)" "unprognostic (7.95e-2)" "unprognostic (7.75e-2)" "unprognostic (2.00e-1)" "unprognostic (6.18e-2)" "unprognostic (1.97e-2)" "unprognostic (4.26e-1)" "unprognostic (1.26e-1)" "unprognostic (1.92e-1)" "unprognostic (4.04e-2)" "unprognostic (1.91e-1)" CDC42BPG "DMPK2, HSMDPKIN, kappa-200, MRCKgamma" ENSG00000171219 "CDC42 binding protein kinase gamma" Q6DT37 11 64823052-64844653 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.8;skin 1: 31.5" "Cell type enhanced" "Detected in many" "Colonocytes: 33.7;Esophageal apical cells: 34.2;Foveolar cells: 37.5" "Group enriched" "Detected in some" 6 "choroid plexus epithelial cell: 5.5;ependymal cell: 4.5;leukocyte: 2.7;upper rhombic lip: 9.8" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in all" 5 "cerebellum: 20.7;choroid plexus: 11.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Lung - Alveolar cells type 1, Prostate - Prostate basal glandular cells, Stomach - Gastric mucous cells" "Region enriched" "Detected in all" 4 "cerebellum: 10.5" "Low region specificity" "Detected in some" "HPA027382, HPA061836" Enhanced Supported Cytosol NA NA "Cluster 2: Non-specific - Mixed function" "Cluster 35: Non-specific - DNA binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 20: Non-specific - Transcription regulation" 16 Cytosol "HPA027382: , HPA061836: " "unprognostic (9.69e-2)" "unprognostic (8.31e-2)" "unprognostic (1.91e-2)" "unprognostic (1.25e-2)" "unprognostic (4.43e-1)" "unprognostic (2.66e-2)" "unprognostic (1.58e-1)" "unprognostic (2.00e-1)" "validated prognostic favorable (8.05e-7)" "validated prognostic favorable (5.43e-4)" "potential prognostic favorable (1.29e-5)" "unprognostic (2.28e-1)" "unprognostic (6.88e-2)" "unprognostic (2.64e-2)" "unprognostic (2.89e-2)" "unprognostic (3.96e-1)" "unprognostic (7.42e-2)" "unprognostic (5.77e-2)" "unprognostic (2.65e-2)" "unprognostic (3.18e-1)" "unprognostic (4.91e-3)" "unprognostic (5.96e-2)" "unprognostic (2.10e-1)" "unprognostic (7.71e-2)" "unprognostic (1.01e-2)" "unprognostic (3.07e-2)" "unprognostic (1.49e-1)" "unprognostic (7.68e-2)" "unprognostic (7.15e-2)" CDC42EP1 "Borg5, CEP1, MSE55" ENSG00000128283 "CDC42 effector protein 1" Q00587 22 37560480-37569405 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast secretory cells: 143.2;Cholangiocytes: 147.6;Esophageal apical cells: 379.4;Esophageal basal cells: 129.7;Esophageal suprabasal cells: 126.6;Extravillous trophoblasts: 157.1;Fallopian secretory cells: 173.8;Gastric chief cells: 132.1;Mucous neck cells: 157.9;Pancreatic duct cells: 195.7;Parietal cells: 139.7" "Cell type enhanced" "Detected in many" "oligodendrocyte: 72.2;pericyte: 38.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "classical monocyte: 7.3;intermediate monocyte: 1.9;myeloid DC: 2.4" "Group enriched" "Detected in many" 10 "dendritic cells: 2.4;monocytes: 7.3" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006379, HPA076536" Approved Supported "Nucleoplasm,Plasma membrane,Actin filaments" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 70: Non-specific - Protein processing" "Cluster 11: White matter - Signal transduction" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 20 "Plasma membrane" "Nucleoplasm, Actin filaments" "HPA006379: , HPA076536: " "unprognostic (1.84e-2)" "unprognostic (1.18e-1)" "unprognostic (2.93e-1)" "unprognostic (2.50e-2)" "unprognostic (2.51e-1)" "unprognostic (4.29e-1)" "unprognostic (1.77e-1)" "unprognostic (2.56e-1)" "unprognostic (2.47e-1)" "unprognostic (1.06e-1)" "unprognostic (9.23e-2)" "unprognostic (1.74e-2)" "unprognostic (1.31e-1)" "unprognostic (4.14e-2)" "unprognostic (3.54e-2)" "unprognostic (6.89e-2)" "unprognostic (1.02e-2)" "unprognostic (2.65e-2)" "unprognostic (1.91e-1)" "unprognostic (1.19e-1)" "unprognostic (1.20e-1)" "unprognostic (2.52e-2)" "unprognostic (6.24e-2)" "unprognostic (1.35e-1)" "unprognostic (1.78e-1)" "unprognostic (4.62e-2)" "unprognostic (3.87e-2)" "unprognostic (2.22e-2)" "unprognostic (1.20e-1)" "unprognostic (5.75e-2)" "unprognostic (1.19e-1)" CDC42EP2 "BORG1, CEP2" ENSG00000149798 "CDC42 effector protein 2" O14613 11 65314866-65322417 "Predicted intracellular proteins" "Cell shape" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 5 "Oligodendrocytes: 17.4;Papillary tip epithelial cells: 5.7;Podocytes: 18.1;Renal collecting duct principal cells: 6.8" "Cell type enhanced" "Detected in many" "endothelial cell: 15.9;fibroblast: 15.7;oligodendrocyte: 24.6;pericyte: 14.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "classical monocyte: 50.8;intermediate monocyte: 120.0;neutrophil: 172.5;non-classical monocyte: 90.7" "Group enriched" "Detected in many" 13 "granulocytes: 172.5;monocytes: 120.0" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038562 Approved Approved Vesicles,Microtubules,Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 11: White matter - Signal transduction" "Cluster 72: Neuronal - Signal transduction" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 8 "Microtubules, Cytosol" Vesicles "HPA038562: " "unprognostic (3.96e-2)" "unprognostic (5.17e-1)" "unprognostic (1.28e-1)" "unprognostic (1.81e-3)" "unprognostic (1.33e-1)" "unprognostic (2.46e-1)" "unprognostic (2.60e-2)" "unprognostic (1.07e-2)" "unprognostic (3.05e-2)" "unprognostic (1.16e-1)" "unprognostic (6.48e-3)" "unprognostic (5.41e-3)" "unprognostic (7.21e-2)" "validated prognostic unfavorable (3.27e-5)" "validated prognostic unfavorable (4.74e-5)" "potential prognostic unfavorable (5.66e-5)" "unprognostic (6.91e-2)" "unprognostic (2.01e-1)" "unprognostic (2.33e-1)" "unprognostic (4.96e-3)" "unprognostic (9.10e-3)" "unprognostic (2.86e-3)" "unprognostic (1.26e-1)" "unprognostic (2.31e-1)" "unprognostic (1.47e-1)" "unprognostic (1.41e-1)" "unprognostic (1.77e-1)" "unprognostic (6.26e-2)" "unprognostic (7.42e-2)" "unprognostic (8.61e-2)" "unprognostic (8.00e-2)" CDC42EP3 "BORG2, CEP3, UB1" ENSG00000163171 "CDC42 effector protein 3" Q9UKI2 2 37641882-37738468 "Predicted intracellular proteins" "Cell shape" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Mast cells: 314.0;Melanocytes: 563.7;Neutrophils: 1010.4;Podocytes: 296.3;Thymic myoid cells: 315.4" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 100.7;leukocyte: 104.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034986, HPA061792" Approved Supported "Plasma membrane,Actin filaments" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 4 "Plasma membrane, Actin filaments" "HPA034986: , HPA061792: " "unprognostic (9.31e-3)" "unprognostic (1.01e-1)" "unprognostic (2.95e-2)" "unprognostic (1.07e-2)" "unprognostic (9.34e-3)" "unprognostic (6.23e-2)" "unprognostic (1.52e-2)" "unprognostic (1.84e-2)" "unprognostic (2.51e-3)" "unprognostic (4.12e-2)" "potential prognostic favorable (4.20e-5)" "unprognostic (1.61e-3)" "unprognostic (9.67e-2)" "unprognostic (1.16e-1)" "unprognostic (2.37e-2)" "unprognostic (4.04e-2)" "unprognostic (2.11e-2)" "unprognostic (2.13e-1)" "unprognostic (8.02e-2)" "unprognostic (7.77e-2)" "unprognostic (1.69e-2)" "unprognostic (2.05e-2)" "unprognostic (1.22e-1)" "unprognostic (3.10e-1)" "unprognostic (1.29e-1)" "unprognostic (3.99e-1)" "unprognostic (2.56e-1)" "unprognostic (1.20e-2)" "unprognostic (1.81e-1)" "unprognostic (6.41e-2)" "unprognostic (3.37e-2)" CDC42EP4 "BORG4, CEP4, KAIA1777, MGC17125, MGC3740" ENSG00000179604 "CDC42 effector protein 4" Q9H3Q1 17 73283624-73312005 "Predicted intracellular proteins" "Cell shape" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bergmann glia: 303.6;Müller glia: 789.5;Pituicytes/FSCs: 263.2;Respiratory basal cells: 263.7;Retinal horizontal cells: 486.8" "Cell type enhanced" "Detected in many" "astrocyte: 157.1;Bergmann glia: 319.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 20.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023335, HPA024797" Approved Supported Supported "Plasma membrane,Actin filaments,Microtubules" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 70: Non-specific - Protein processing" "Cluster 44: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 11: Muller glia cells - Retinal homeostasis" 20 "Actin filaments, Microtubules" "Plasma membrane" "HPA023335: , HPA024797: " "unprognostic (2.58e-2)" "unprognostic (6.64e-2)" "unprognostic (1.23e-1)" "unprognostic (5.28e-2)" "unprognostic (9.37e-3)" "unprognostic (2.20e-2)" "unprognostic (3.87e-2)" "unprognostic (2.25e-2)" "unprognostic (7.14e-3)" "unprognostic (1.66e-1)" "potential prognostic favorable (9.34e-4)" "unprognostic (6.61e-3)" "unprognostic (1.13e-1)" "unprognostic (2.35e-3)" "unprognostic (2.53e-3)" "unprognostic (1.30e-1)" "unprognostic (2.27e-1)" "unprognostic (1.57e-1)" "unprognostic (1.01e-1)" "unprognostic (9.84e-2)" "unprognostic (9.10e-2)" "unprognostic (2.05e-1)" "unprognostic (3.77e-2)" "unprognostic (1.70e-1)" "unprognostic (4.26e-2)" "unprognostic (1.82e-1)" "unprognostic (1.29e-1)" "unprognostic (1.36e-1)" "unprognostic (4.06e-1)" "unprognostic (3.21e-1)" "unprognostic (4.18e-2)" CDC42EP5 "Borg3, CEP5" ENSG00000167617 "CDC42 effector protein 5" Q6NZY7 19 54465026-54473296 "Predicted intracellular proteins" "Cell shape" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 79.6" "Cell type enhanced" "Detected in some" "Colonocytes: 5.2;Endometrial secretory cells: 12.0;Enterocytes: 5.5;Goblet cells: 8.2;Lymphatic endothelial cells: 5.2;Papillary tip epithelial cells: 34.5;Prostatic club cells: 19.1;Prostatic glandular cells: 5.2;Prostatic hillock cells: 12.4;Renal collecting duct principal cells: 7.3;Urothelial cells: 10.1" "Cell type enhanced" "Detected in many" "endothelial cell: 20.2;fibroblast: 32.6;pericyte: 13.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Fibroblasts, Prostate - Prostate glandular cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043449 Approved Approved "Nucleoplasm,Primary cilium,Cytosol" NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 47: Endothelial cells - Vasculature" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 105: Non-specific - Mixed function" 1 "Primary cilium" "Nucleoplasm, Cytosol" "HPA043449: " "unprognostic (1.69e-1)" "unprognostic (1.09e-1)" "unprognostic (1.03e-1)" "unprognostic (3.65e-2)" "unprognostic (7.85e-2)" "unprognostic (3.77e-3)" "unprognostic (8.22e-2)" "unprognostic (5.87e-2)" "unprognostic (2.08e-2)" "unprognostic (1.62e-2)" "unprognostic (3.65e-2)" "unprognostic (5.69e-2)" "unprognostic (6.81e-2)" "unprognostic (2.39e-2)" "unprognostic (1.42e-1)" "unprognostic (3.48e-2)" "potential prognostic unfavorable (2.96e-4)" "unprognostic (1.99e-1)" "unprognostic (6.98e-2)" "unprognostic (1.80e-1)" "unprognostic (1.31e-1)" "unprognostic (4.13e-2)" "unprognostic (1.14e-1)" "unprognostic (1.84e-2)" "unprognostic (2.25e-1)" "unprognostic (2.49e-2)" "unprognostic (3.13e-2)" CDC42SE1 "SCIP1, SPEC1" ENSG00000197622 "CDC42 small effector 1" Q9NRR8 1 151050971-151070325 "Predicted intracellular proteins" "Cell shape, Phagocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 585.5;Neutrophils: 679.9;NK-cells: 268.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027634 Approved Supported "Cell Junctions" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 45: Non-specific - Nuclear processes" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 3 "Cell Junctions" "HPA027634: " "unprognostic (5.57e-2)" "unprognostic (3.05e-2)" "unprognostic (2.20e-2)" "unprognostic (1.95e-1)" "unprognostic (1.67e-1)" "unprognostic (1.64e-1)" "unprognostic (2.36e-1)" "unprognostic (4.53e-3)" "unprognostic (3.30e-1)" "unprognostic (7.30e-2)" "unprognostic (2.53e-1)" "unprognostic (1.71e-1)" "unprognostic (4.53e-3)" "unprognostic (7.95e-3)" "unprognostic (1.61e-1)" "unprognostic (4.21e-2)" "unprognostic (5.87e-2)" "unprognostic (1.60e-1)" "unprognostic (3.47e-1)" "unprognostic (2.30e-1)" "unprognostic (1.33e-2)" "unprognostic (4.80e-2)" "unprognostic (6.09e-2)" "unprognostic (2.47e-1)" "unprognostic (4.78e-2)" "unprognostic (1.93e-1)" "unprognostic (9.27e-2)" "unprognostic (2.23e-1)" "unprognostic (1.44e-1)" "unprognostic (1.64e-1)" "unprognostic (2.14e-1)" CDC42SE2 "FLJ21967, SPEC2" ENSG00000158985 "CDC42 small effector 2" Q9NRR3 5 131245493-131398447 "Predicted intracellular proteins" "Cell shape, Phagocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "B-cells: 877.1;Neutrophil progenitors: 791.0;Neutrophils: 955.4;NK-cells: 926.7;T-cells: 1260.2" "Cell type enhanced" "Detected in all" "leukocyte: 937.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - T-cells, Kidney - Endothelial cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038624 Enhanced NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 14: Neurons - Synaptic function" "Cluster 55: Lymphoma - Immune response" "Cluster 9: T-cells - Adaptive immunity: Regulation" 5 "HPA038624: " "potential prognostic favorable (1.12e-4)" "unprognostic (3.02e-2)" "unprognostic (1.85e-1)" "unprognostic (2.85e-1)" "unprognostic (6.72e-3)" "unprognostic (4.20e-3)" "unprognostic (1.54e-1)" "unprognostic (1.33e-1)" "unprognostic (3.44e-2)" "unprognostic (2.11e-2)" "potential prognostic favorable (5.50e-8)" "unprognostic (3.39e-3)" "unprognostic (2.36e-1)" "unprognostic (8.63e-3)" "unprognostic (2.32e-2)" "unprognostic (5.60e-2)" "unprognostic (1.18e-1)" "unprognostic (6.31e-2)" "unprognostic (1.33e-1)" "unprognostic (4.09e-1)" "unprognostic (1.84e-1)" "unprognostic (2.41e-1)" "unprognostic (3.86e-1)" "unprognostic (2.75e-1)" "unprognostic (1.21e-2)" "unprognostic (4.18e-2)" "unprognostic (1.92e-1)" "unprognostic (4.74e-2)" "unprognostic (1.85e-1)" "unprognostic (1.17e-1)" "unprognostic (2.20e-1)" CDC45 "CDC45L, CDC45L2" ENSG00000093009 "Cell division cycle 45" O75419 22 19479457-19520612 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA replication" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 24.0;lymphoid tissue: 19.0;testis: 26.6" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 56.9;Early primary spermatocytes: 116.0;Early spermatids: 132.2;Erythrocyte progenitors: 67.5;Extravillous trophoblasts: 27.8;Late primary spermatocytes: 109.2;Megakaryocyte progenitors: 40.1;Monocyte progenitors: 27.9;Oocytes: 50.7" "Cell type enriched" "Detected in single" 7 "endothelial cell: 4.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000614, CAB009459" Enhanced Supported Nucleoplasm,Centrosome,Cytosol NA Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 47: Endothelial cells - Vasculature" "Cluster 66: Non-specific - Mitochondria" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 58 Nucleoplasm "Centrosome, Cytosol" "CAB009459: , HPA000614: " "unprognostic (1.18e-1)" "unprognostic (2.17e-2)" "unprognostic (1.50e-1)" "unprognostic (1.56e-2)" "unprognostic (2.40e-2)" "unprognostic (4.04e-1)" "unprognostic (3.02e-1)" "unprognostic (5.83e-3)" "unprognostic (2.37e-1)" "validated prognostic unfavorable (1.84e-10)" "validated prognostic unfavorable (1.81e-4)" "potential prognostic unfavorable (5.82e-5)" "validated prognostic unfavorable (2.90e-7)" "validated prognostic unfavorable (4.14e-8)" "potential prognostic unfavorable (3.62e-5)" "unprognostic (2.17e-3)" "unprognostic (4.64e-2)" "unprognostic (3.53e-2)" "unprognostic (2.16e-2)" "unprognostic (6.05e-3)" "potential prognostic unfavorable (4.08e-4)" "unprognostic (6.70e-3)" "unprognostic (8.00e-2)" "unprognostic (2.07e-2)" "unprognostic (4.99e-2)" "unprognostic (1.56e-2)" "unprognostic (2.18e-2)" "unprognostic (6.13e-2)" "unprognostic (7.46e-2)" "unprognostic (1.24e-1)" CDC5L "CDC5, CEF1, hCDC5, PCDC5RP" ENSG00000096401 "Cell division cycle 5 like" Q99459 6 44387706-44450425 "Disease related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Cell cycle, DNA damage, DNA repair, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Activator, DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 380.7;Late spermatids: 413.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006302, HPA011361, CAB012275" Supported Supported Nucleoplasm NA NA 4500 "Cluster 25: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 267 Nucleoplasm "CAB012275: , HPA006302: , HPA011361: " "unprognostic (2.14e-1)" "unprognostic (1.15e-1)" "unprognostic (7.79e-2)" "unprognostic (1.04e-1)" "unprognostic (1.78e-2)" "unprognostic (3.67e-1)" "unprognostic (1.76e-2)" "unprognostic (7.74e-3)" "unprognostic (2.85e-1)" "potential prognostic unfavorable (4.26e-4)" "potential prognostic favorable (3.75e-6)" "unprognostic (4.95e-3)" "unprognostic (2.17e-1)" "unprognostic (1.90e-1)" "unprognostic (9.50e-2)" "unprognostic (1.91e-1)" "unprognostic (7.01e-2)" "unprognostic (1.39e-1)" "unprognostic (8.96e-2)" "unprognostic (1.28e-1)" "unprognostic (6.66e-2)" "unprognostic (5.52e-2)" "unprognostic (1.95e-1)" "unprognostic (2.52e-1)" "unprognostic (3.47e-2)" "unprognostic (1.23e-1)" "unprognostic (3.29e-3)" "unprognostic (8.64e-3)" "unprognostic (3.56e-1)" "unprognostic (7.13e-2)" "unprognostic (2.44e-1)" CDC6 CDC18L ENSG00000094804 "Cell division cycle 6" Q99741 17 40287879-40304657 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA replication, Mitosis" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.7;lymphoid tissue: 16.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 27.3;Differentiating spermatogonia: 30.2;Early primary spermatocytes: 120.0;Erythrocyte progenitors: 69.4;Esophageal basal cells: 24.6;Extravillous trophoblasts: 39.5;Gastric progenitor cells: 25.6;Megakaryocyte progenitors: 39.2;Migrating cytotrophoblasts: 36.0;Monocyte progenitors: 25.4;Oocytes: 59.9" "Cell type enhanced" "Detected in many" "upper-layer intratelencephalic: 5.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 3.6" "Group enriched" "Detected in many" 6 "dendritic cells: 3.6;NK-cells: 1.5;T-cells: 2.4" "Low cancer specificity" "Detected in all" "Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" "HPA050114, HPA065070" Approved Approved "Nucleoplasm,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes Yes "Cluster 13: Non-specific - Mitochondria" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 53: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 3: Early primary spermatocytes - Early meiosis" 29 "Nucleoplasm, Cytosol" "Cytokinetic bridge, Mitotic spindle" "HPA050114: , HPA065070: " "unprognostic (3.46e-2)" "unprognostic (2.31e-1)" "unprognostic (2.34e-2)" "unprognostic (1.32e-1)" "unprognostic (9.50e-2)" "unprognostic (5.76e-3)" "unprognostic (2.13e-1)" "unprognostic (1.50e-3)" "unprognostic (5.34e-2)" "unprognostic (1.81e-3)" "validated prognostic unfavorable (6.41e-4)" "validated prognostic unfavorable (3.11e-4)" "potential prognostic unfavorable (2.73e-9)" "validated prognostic unfavorable (4.45e-6)" "validated prognostic unfavorable (6.25e-9)" "potential prognostic unfavorable (6.58e-5)" "unprognostic (5.42e-3)" "unprognostic (5.84e-2)" "unprognostic (4.95e-2)" "unprognostic (8.63e-2)" "unprognostic (3.14e-2)" "validated prognostic unfavorable (5.64e-4)" "validated prognostic unfavorable (2.90e-4)" "unprognostic (5.14e-2)" "unprognostic (2.19e-3)" "unprognostic (3.29e-3)" "unprognostic (5.42e-3)" "unprognostic (6.04e-3)" "unprognostic (2.56e-1)" "unprognostic (6.25e-2)" "unprognostic (1.58e-2)" CDC7 "CDC7L1, HsCdc7, Hsk1, huCdc7" ENSG00000097046 "Cell division cycle 7" O00311 1 91500851-91525764 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 15.8" "Cell type enriched" "Detected in many" 4 "Breast lactating cells: 298.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in all" 7 "Gallbladder cancer: 199.8" "Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002669, HPA035831" Enhanced Supported "Nucleoplasm,Cytokinetic bridge,Mitotic spindle" Yes No "Cluster 30: Non-specific - DNA binding" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 2: Neurons - Nucleosome" "Cluster 37: Non-specific - mRNA processing" "Cluster 4: Breast lactating luminal cells - Lactation" 55 Nucleoplasm "Cytokinetic bridge, Mitotic spindle" "CAB002669: , HPA035831: " "unprognostic (1.02e-1)" "unprognostic (1.07e-1)" "unprognostic (5.79e-3)" "unprognostic (3.87e-1)" "unprognostic (9.50e-2)" "unprognostic (1.64e-1)" "unprognostic (2.05e-1)" "unprognostic (7.05e-3)" "unprognostic (5.37e-3)" "potential prognostic unfavorable (1.00e-4)" "potential prognostic unfavorable (3.45e-6)" "unprognostic (1.08e-1)" "unprognostic (3.27e-2)" "potential prognostic unfavorable (3.09e-6)" "unprognostic (4.20e-3)" "unprognostic (4.27e-3)" "unprognostic (6.50e-3)" "unprognostic (4.97e-3)" "potential prognostic favorable (4.14e-4)" "unprognostic (1.61e-2)" "unprognostic (1.54e-2)" "unprognostic (1.12e-1)" "unprognostic (1.69e-2)" "unprognostic (3.11e-2)" "unprognostic (7.12e-3)" "unprognostic (1.83e-2)" "unprognostic (2.60e-2)" "unprognostic (6.34e-2)" "unprognostic (1.80e-1)" "unprognostic (8.98e-2)" "unprognostic (5.90e-2)" CDC73 "C1orf28, FIHP, HRPT1, HRPT2, parafibromin" ENSG00000134371 "Cell division cycle 73" Q6P1J9 1 193121983-193254815 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation, Wnt signaling pathway" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002326, CAB016359, HPA069324" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" 105 Nucleoplasm Cytosol "CAB016359: , HPA002326: , HPA069324: " "unprognostic (2.13e-1)" "unprognostic (1.85e-2)" "unprognostic (3.50e-2)" "unprognostic (2.34e-1)" "unprognostic (2.53e-1)" "unprognostic (1.30e-1)" "unprognostic (7.06e-3)" "unprognostic (1.52e-1)" "unprognostic (5.71e-2)" "unprognostic (3.68e-3)" "potential prognostic favorable (2.69e-6)" "unprognostic (4.97e-2)" "unprognostic (1.26e-3)" "unprognostic (3.85e-3)" "unprognostic (8.97e-2)" "unprognostic (1.10e-2)" "unprognostic (4.59e-1)" "unprognostic (1.12e-1)" "unprognostic (4.48e-2)" "unprognostic (1.01e-1)" "unprognostic (1.26e-3)" "unprognostic (1.42e-2)" "unprognostic (7.60e-3)" "unprognostic (1.36e-1)" "unprognostic (2.07e-1)" "unprognostic (8.77e-2)" "unprognostic (2.92e-1)" "unprognostic (9.61e-2)" "unprognostic (2.47e-1)" "unprognostic (8.47e-3)" "unprognostic (3.63e-1)" CDCA2 "PPP1R81, Repo-Man" ENSG00000184661 "Cell division cycle associated 2" Q69YH5 8 25459199-25507911 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 6.1;lymphoid tissue: 10.6;testis: 18.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 37.3;Differentiating spermatogonia: 52.2;Early primary spermatocytes: 53.5;Early spermatids: 39.2;Erythrocyte progenitors: 64.4;Extravillous trophoblasts: 29.8;Late primary spermatocytes: 108.7;Late spermatids: 32.5;Megakaryocyte progenitors: 40.2;Monocyte progenitors: 73.7;Neutrophil progenitors: 31.3;Undifferentiated spermatogonia: 40.4" "Cell type enhanced" "Detected in some" "lower rhombic lip: 3.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA026293, HPA030049" Enhanced Supported Nucleoplasm,Cytosol Yes Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 40: Non-specific - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 13 Nucleoplasm Cytosol "HPA026293: , HPA030049: " "unprognostic (1.07e-3)" "unprognostic (2.77e-1)" "unprognostic (1.59e-1)" "unprognostic (7.25e-3)" "unprognostic (3.90e-3)" "unprognostic (1.38e-2)" "unprognostic (9.81e-2)" "unprognostic (3.96e-2)" "unprognostic (6.26e-3)" "unprognostic (2.68e-2)" "potential prognostic unfavorable (1.19e-5)" "potential prognostic unfavorable (9.85e-6)" "unprognostic (1.56e-2)" "unprognostic (3.23e-2)" "unprognostic (2.63e-1)" "unprognostic (3.51e-1)" "unprognostic (9.93e-2)" "potential prognostic unfavorable (8.97e-4)" "unprognostic (1.42e-3)" "unprognostic (3.93e-2)" "unprognostic (1.54e-1)" "unprognostic (2.47e-2)" "unprognostic (1.25e-1)" "unprognostic (9.60e-2)" CDCA3 "GRCC8, TOME-1" ENSG00000111665 "Cell division cycle associated 3" Q99618 12 6844793-6851292 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 28.4;retina: 61.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 68.4;Cytotrophoblasts: 32.5;Early primary spermatocytes: 42.2;Enteric transient amplifying cells: 49.1;Enterocytes: 60.2;Erythrocyte progenitors: 31.5;Esophageal basal cells: 36.8;Extravillous trophoblasts: 84.3;Gastric progenitor cells: 28.2;Hofbauer cells: 29.8;Late primary spermatocytes: 92.6;Megakaryocyte progenitors: 30.1;Migrating cytotrophoblasts: 52.2;Monocyte progenitors: 39.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "T-reg: 4.3" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA026587 Approved Cytosol NA Yes "Cluster 14: Non-specific - Unknown function" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 37: Neurons - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 27: Non-specific - Cell proliferation" 29 Cytosol "HPA026587: " "unprognostic (1.67e-2)" "unprognostic (6.64e-2)" "unprognostic (1.52e-1)" "unprognostic (2.56e-1)" "unprognostic (5.04e-2)" "unprognostic (6.76e-2)" "unprognostic (1.49e-1)" "unprognostic (5.83e-3)" "unprognostic (1.70e-2)" "potential prognostic unfavorable (4.03e-4)" "validated prognostic unfavorable (5.06e-10)" "validated prognostic unfavorable (2.75e-7)" "potential prognostic unfavorable (1.46e-7)" "validated prognostic unfavorable (2.09e-6)" "validated prognostic unfavorable (1.08e-10)" "potential prognostic unfavorable (3.67e-6)" "unprognostic (7.59e-3)" "unprognostic (1.45e-2)" "unprognostic (4.19e-1)" "unprognostic (1.41e-1)" "unprognostic (2.61e-2)" "validated prognostic unfavorable (2.43e-4)" "validated prognostic unfavorable (1.76e-4)" "unprognostic (5.40e-2)" "unprognostic (1.62e-1)" "unprognostic (8.08e-3)" "unprognostic (1.51e-1)" "unprognostic (3.24e-2)" "unprognostic (1.01e-1)" "unprognostic (1.37e-1)" "unprognostic (7.25e-2)" CDCA4 "FLJ20764, Hepp" ENSG00000170779 "Cell division cycle associated 4" Q9BXL8 14 105009573-105021083 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 52.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 58.5;Cytotrophoblasts: 95.5;Differentiating spermatogonia: 90.0;Early primary spermatocytes: 66.2;Erythrocyte progenitors: 94.7;Esophageal basal cells: 93.8;Extravillous trophoblasts: 192.0;Migrating cytotrophoblasts: 138.6;Oocytes: 73.7;Suprabasal keratinocytes: 55.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064971 Supported "Nucleoplasm,Plasma membrane,Cytosol" NA Yes "Cluster 3: Non-specific - Nuclear processes" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 25: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 27: Non-specific - Cell proliferation" 49 Nucleoplasm "Plasma membrane, Cytosol" "HPA064971: " "potential prognostic unfavorable (6.12e-4)" "unprognostic (1.62e-2)" "unprognostic (9.24e-3)" "unprognostic (2.34e-1)" "unprognostic (1.02e-1)" "unprognostic (3.68e-2)" "unprognostic (1.65e-1)" "unprognostic (1.20e-1)" "unprognostic (4.74e-2)" "unprognostic (1.60e-2)" "unprognostic (7.30e-2)" "unprognostic (1.39e-1)" "potential prognostic unfavorable (9.76e-4)" "validated prognostic unfavorable (6.72e-4)" "validated prognostic unfavorable (5.71e-5)" "validated prognostic unfavorable (1.33e-4)" "validated prognostic unfavorable (8.93e-4)" "unprognostic (2.58e-2)" "unprognostic (1.28e-1)" "unprognostic (2.76e-1)" "unprognostic (3.46e-1)" "unprognostic (1.10e-3)" "unprognostic (1.45e-3)" "unprognostic (1.23e-2)" "unprognostic (2.51e-1)" "unprognostic (2.68e-1)" "unprognostic (3.81e-2)" "unprognostic (1.79e-1)" "unprognostic (3.57e-1)" "unprognostic (1.20e-1)" "unprognostic (2.38e-1)" CDCA5 ENSG00000146670 "Cell division cycle associated 5" Q96FF9 11 65066300-65084164 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 50.4;lymphoid tissue: 25.7;testis: 37.1" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 48.2;Early primary spermatocytes: 36.3;Early spermatids: 49.1;Erythrocyte progenitors: 47.5;Esophageal basal cells: 31.1;Extravillous trophoblasts: 46.9;Late primary spermatocytes: 103.7;Late spermatids: 208.1;Megakaryocyte progenitors: 38.3;Migrating cytotrophoblasts: 45.4;Monocyte progenitors: 59.4;Neutrophil progenitors: 28.2;Oocytes: 32.2" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "NK-cell: 2.8;T-reg: 2.0" "Group enriched" "Detected in many" 5 "NK-cells: 2.8;T-cells: 2.0" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Thyroid gland - Mitotic cells (Thyroid)" "Region enhanced" "Detected in single" "white matter: 1.4" "Low region specificity" "Detected in all" "HPA023691, HPA076007" Enhanced Enhanced Nucleoplasm Yes Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 24: Non-specific - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 32 Nucleoplasm "HPA023691: , HPA076007: " "unprognostic (3.18e-2)" "unprognostic (2.32e-2)" "unprognostic (8.37e-2)" "unprognostic (1.80e-1)" "unprognostic (3.79e-1)" "unprognostic (2.71e-1)" "unprognostic (1.84e-1)" "unprognostic (7.87e-3)" "unprognostic (2.94e-1)" "potential prognostic unfavorable (3.44e-4)" "validated prognostic unfavorable (1.23e-7)" "validated prognostic unfavorable (4.34e-5)" "potential prognostic unfavorable (1.44e-7)" "validated prognostic unfavorable (5.12e-6)" "validated prognostic unfavorable (5.37e-9)" "validated prognostic unfavorable (3.12e-5)" "validated prognostic unfavorable (5.36e-5)" "unprognostic (3.20e-1)" "unprognostic (1.48e-2)" "unprognostic (1.33e-1)" "unprognostic (2.95e-1)" "potential prognostic unfavorable (6.41e-6)" "unprognostic (3.56e-3)" "unprognostic (1.72e-2)" "unprognostic (6.61e-2)" "unprognostic (1.99e-2)" "unprognostic (5.59e-3)" "unprognostic (3.41e-3)" "unprognostic (2.56e-1)" "unprognostic (7.72e-2)" "unprognostic (5.52e-2)" CDCA7 "FLJ14736, JPO1" ENSG00000144354 "Cell division cycle associated 7" Q9BWT1 2 173354820-173368997 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 26.5;lymphoid tissue: 41.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 56.6;Decidual stromal cells: 63.0;Enteric stem cells: 206.7;Enteric transient amplifying cells: 109.7;Esophageal basal cells: 48.7;Gastric progenitor cells: 103.8;Leydig cells: 92.6;Megakaryocyte progenitors: 52.7;Migrating cytotrophoblasts: 52.0;Monocyte progenitors: 57.6;Mucous neck cells: 60.0;Paneth cells: 170.2" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 35.7;LAMP5-LHX6 and Chandelier: 37.4" "Cancer enhanced" "Detected in all" "Rectum Adenocarcinoma (TCGA): 92.1" "Region enriched" "Detected in many" 6 "choroid plexus: 12.2" "Immune cell enhanced" "Detected in many" "T-reg: 8.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA005565 Supported Nucleoplasm,Cytosol No Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 36: Choroid plexus - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 27: Non-specific - Cell proliferation" 2 "Nucleoplasm, Cytosol" "HPA005565: " "unprognostic (2.03e-1)" "unprognostic (1.56e-3)" "unprognostic (1.25e-1)" "unprognostic (5.77e-2)" "unprognostic (1.25e-1)" "unprognostic (8.67e-2)" "unprognostic (1.42e-1)" "unprognostic (3.42e-1)" "unprognostic (7.38e-2)" "unprognostic (1.32e-2)" "potential prognostic unfavorable (1.16e-7)" "unprognostic (2.06e-3)" "potential prognostic unfavorable (7.85e-6)" "unprognostic (2.66e-3)" "unprognostic (3.32e-3)" "unprognostic (8.00e-2)" "unprognostic (2.87e-2)" "unprognostic (2.72e-2)" "unprognostic (4.35e-2)" "unprognostic (1.62e-1)" "unprognostic (1.04e-2)" "unprognostic (3.64e-1)" "unprognostic (2.02e-2)" "unprognostic (4.08e-2)" "unprognostic (1.97e-2)" "unprognostic (1.35e-1)" "unprognostic (1.60e-3)" "unprognostic (2.21e-3)" "unprognostic (2.53e-1)" "unprognostic (1.24e-1)" "unprognostic (2.06e-1)" CDCA7L "JPO2, R1, RAM2" ENSG00000164649 "Cell division cycle associated 7 like" Q96GN5 7 21900899-21945903 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 48.8" "Cell type enhanced" "Detected in many" "Neutrophil progenitors: 180.9;Oocytes: 262.5;Undifferentiated spermatogonia: 81.9" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 32.3;endothelial cell: 22.8;ependymal cell: 35.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 101.4;naive B-cell: 125.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Kidney - Fibroblasts, Lung - Alveolar cells type 2, Prostate - Prostate basal glandular cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 4 "olfactory bulb: 12.4" "HPA027169, HPA074623" Approved Supported "Nucleoplasm,Nucleoli,Nucleoli fibrillar center,Cytosol" No Yes "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 67: Non-specific - Unknown function" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 64 "Nucleoplasm, Nucleoli" "Nucleoli fibrillar center, Cytosol" "HPA027169: , HPA074623: " "unprognostic (2.95e-1)" "unprognostic (4.66e-3)" "unprognostic (3.38e-2)" "unprognostic (1.19e-1)" "unprognostic (2.10e-1)" "unprognostic (2.01e-2)" "unprognostic (3.62e-1)" "unprognostic (7.51e-3)" "unprognostic (3.59e-1)" "unprognostic (3.65e-2)" "unprognostic (1.61e-3)" "unprognostic (2.42e-2)" "unprognostic (1.71e-1)" "potential prognostic unfavorable (6.12e-5)" "unprognostic (6.32e-2)" "unprognostic (5.65e-2)" "unprognostic (3.80e-2)" "unprognostic (3.66e-2)" "unprognostic (2.17e-2)" "unprognostic (2.34e-1)" "unprognostic (1.20e-1)" "unprognostic (1.50e-2)" "unprognostic (2.58e-1)" "unprognostic (2.18e-1)" "unprognostic (6.45e-3)" "unprognostic (9.76e-2)" "unprognostic (4.03e-1)" "unprognostic (1.19e-1)" "unprognostic (2.35e-1)" "unprognostic (2.47e-1)" "unprognostic (1.63e-1)" CDCA8 "BOR, DasraB, FLJ12042, MESRGP" ENSG00000134690 "Cell division cycle associated 8" Q53HL2 1 37692481-37709719 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 31.6;lymphoid tissue: 36.1;testis: 21.6" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 56.0;Early primary spermatocytes: 98.7;Enteric transient amplifying cells: 45.0;Erythrocyte progenitors: 69.1;Esophageal basal cells: 31.2;Extravillous trophoblasts: 35.0;Gastric progenitor cells: 39.7;Late primary spermatocytes: 45.6;Megakaryocyte progenitors: 42.5;Migrating cytotrophoblasts: 29.9;Monocyte progenitors: 84.0;Neutrophil progenitors: 45.3;Oocytes: 96.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" "HPA028120, HPA028258, HPA028783, CAB040294" Enhanced Supported "Nucleoplasm,Nucleoli,Cytokinetic bridge" Yes Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 33: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 27: Non-specific - Cell proliferation" 31 Nucleoli "Nucleoplasm, Cytokinetic bridge" "CAB040294: , HPA028120: , HPA028258: , HPA028783: " "unprognostic (2.11e-1)" "unprognostic (8.72e-2)" "unprognostic (2.31e-2)" "unprognostic (4.01e-1)" "unprognostic (3.28e-2)" "unprognostic (5.59e-2)" "unprognostic (1.34e-1)" "unprognostic (8.25e-2)" "unprognostic (1.39e-1)" "potential prognostic unfavorable (3.91e-4)" "validated prognostic unfavorable (5.31e-11)" "validated prognostic unfavorable (1.84e-4)" "potential prognostic unfavorable (2.78e-7)" "validated prognostic unfavorable (4.71e-11)" "validated prognostic unfavorable (1.90e-8)" "potential prognostic unfavorable (1.63e-4)" "unprognostic (2.46e-3)" "unprognostic (2.04e-2)" "unprognostic (1.56e-2)" "unprognostic (3.19e-1)" "unprognostic (2.18e-2)" "potential prognostic unfavorable (8.18e-4)" "unprognostic (1.74e-1)" "unprognostic (4.80e-2)" "unprognostic (1.61e-1)" "unprognostic (1.66e-1)" "unprognostic (5.18e-3)" "unprognostic (2.71e-2)" "unprognostic (2.71e-1)" "unprognostic (1.46e-1)" "unprognostic (1.03e-1)" CDCP1 "CD318, SIMA135" ENSG00000163814 "CUB domain containing protein 1" Q9H5V8 3 45082277-45146422 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 35.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 311.3;Esophageal apical cells: 310.2;Esophageal basal cells: 179.2;Esophageal suprabasal cells: 213.1;Foveolar cells: 153.3;Ocular epithelial cells: 445.0;Suprabasal keratinocytes: 267.2" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 31.6;choroid plexus epithelial cell: 41.8;deep-layer near-projecting: 64.2" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "choroid plexus: 26.9" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.3;NK-cell: 4.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adipose visceral - Mesothelial cells, Adrenal gland - Macrophages, Heart muscle - Macrophages, Skin - Keratinocyte (other), Spleen - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA010978, HPA010979, HPA011405, CAB025637" Enhanced Approved "Nucleoplasm,Nuclear bodies,Vesicles" "Intracellular and membrane" "No annotated function" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 5 "Nucleoplasm, Vesicles" "Nuclear bodies" "CAB025637: , HPA010978: , HPA010979: , HPA011405: " "unprognostic (1.26e-1)" "unprognostic (3.79e-2)" "unprognostic (4.37e-2)" "unprognostic (4.21e-3)" "unprognostic (6.03e-3)" "unprognostic (9.82e-2)" "unprognostic (9.81e-3)" "unprognostic (2.46e-2)" "unprognostic (5.93e-3)" "unprognostic (2.62e-2)" "validated prognostic unfavorable (6.19e-4)" "validated prognostic unfavorable (3.32e-4)" "unprognostic (1.09e-1)" "unprognostic (2.49e-2)" "unprognostic (2.41e-2)" "potential prognostic unfavorable (3.27e-5)" "unprognostic (1.76e-3)" "unprognostic (1.64e-2)" "unprognostic (6.45e-3)" "unprognostic (6.19e-3)" "unprognostic (3.65e-1)" "potential prognostic unfavorable (1.83e-4)" "unprognostic (2.02e-2)" "unprognostic (5.67e-2)" "unprognostic (1.46e-1)" "unprognostic (1.72e-1)" "unprognostic (6.66e-2)" "unprognostic (7.81e-2)" "unprognostic (2.06e-1)" "unprognostic (1.17e-1)" "unprognostic (1.89e-1)" CDCP2 ENSG00000157211 "CUB domain containing protein 2" Q5VXM1 1 54132687-54153770 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA031143 Uncertain "Secreted - unknown location" "No annotated function" NA NA "Cluster 11: Neuronal - Sensory perception" "Cluster 98: Neurons - Neurotransmission & signaling" "HPA031143: " CDH1 "CD324, UVO, uvomorulin" ENSG00000039068 "Cadherin 1" P12830 16 68737292-68835537 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Cell adhesion" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 186.0" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 1175.0;Endometrial luminal cells: 763.8;Ocular epithelial cells: 1009.0;Pancreatic acinar cells: 821.7;Urothelial cells: 1358.8" "Group enriched" "Detected in many" 8 "choroid plexus epithelial cell: 52.1;committed oligodendrocyte precursor: 41.5;fibroblast: 17.4;oligodendrocyte: 53.1" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 7 "choroid plexus: 43.1" "Group enriched" "Detected in some" 13 "myeloid DC: 1.7;plasmacytoid DC: 4.7" "Lineage enriched" "Detected in single" 19 "dendritic cells: 4.7" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Liver - Hepatocytes, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB000087, HPA004812, CAB028364, CAB072855, CAB072856, CAB072857" Enhanced Supported "Golgi apparatus,Plasma membrane,Cell Junctions" NA NA 130000000 "Cluster 13: Non-specific - Mitochondria" "Cluster 17: Intestine - Digestion" "Cluster 36: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 110 "Plasma membrane, Cell Junctions" "Golgi apparatus" "CAB000087: , CAB028364: , CAB072855: , CAB072856: , CAB072857: , HPA004812: " "unprognostic (2.74e-1)" "unprognostic (3.08e-2)" "unprognostic (8.05e-3)" "unprognostic (6.64e-2)" "unprognostic (1.28e-1)" "unprognostic (3.43e-1)" "unprognostic (2.77e-1)" "unprognostic (9.33e-2)" "unprognostic (2.21e-1)" "unprognostic (9.84e-2)" "potential prognostic favorable (3.08e-8)" "unprognostic (2.11e-3)" "unprognostic (1.17e-2)" "unprognostic (2.04e-2)" "unprognostic (9.35e-2)" "unprognostic (1.57e-1)" "unprognostic (1.61e-2)" "unprognostic (5.62e-2)" "unprognostic (3.69e-3)" "unprognostic (9.81e-2)" "unprognostic (4.14e-1)" "unprognostic (1.66e-2)" "unprognostic (9.66e-3)" "unprognostic (1.57e-1)" "unprognostic (8.58e-3)" "unprognostic (7.03e-2)" "unprognostic (1.23e-1)" "unprognostic (1.87e-1)" "unprognostic (3.60e-1)" "unprognostic (1.22e-1)" "unprognostic (8.51e-2)" CDH10 ENSG00000040731 "Cadherin 10" Q9Y6N8 5 24487100-24644978 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 18.5" "Cell type enhanced" "Detected in some" "Astrocytes: 230.6;Bergmann glia: 829.3;Brain excitatory neurons: 361.2;Brain inhibitory neurons: 224.1;Oligodendrocyte progenitor cells: 618.8;Other brain neurons: 126.5;Pancreatic islet cells: 96.9;Retinal amacrine cells: 157.4;Retinal ganglion cells: 96.6" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in some" 6 "Glioblastoma Multiforme (TCGA): 7.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 7.1;testis cancer: 10.8" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010651, HPA012085" Approved Approved "Nucleoplasm,Cell Junctions" NA NA 510000 "Cluster 10: Brain - Synaptic signal transduction" "Cluster 2: Neurons - Nucleosome" "Cluster 5: Rhabdoid - Unknown function" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 1 "Cell Junctions" Nucleoplasm "HPA010651: , HPA012085: " "unprognostic (2.97e-1)" "unprognostic (2.26e-3)" "unprognostic (1.54e-2)" "unprognostic (9.54e-2)" CDH11 "CAD11, OB" ENSG00000140937 "Cadherin 11" P55287 16 64943753-65126112 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes, Deafness, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 178.8;placenta: 114.8" "Cell type enhanced" "Detected in many" "Astrocytes: 145.3;Brain excitatory neurons: 165.7;Brain inhibitory neurons: 223.2;Decidual stromal cells: 179.5;Endometrial stromal cells: 370.7;Ependymal cells: 181.8;Epicardial cells: 218.3;Fibro-adipogenic progenitors: 200.3;Fibroblasts: 275.8;Müller glia: 217.5;Oligodendrocyte progenitor cells: 238.6;Ovarian stromal cells: 250.4;Peritubular myoid cells: 166.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 102.5" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Adrenal gland - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblasts_1, Skeletal muscle - Fibroblasts, Spleen - Endothelial cells, Stomach - Fibroblasts, Testis - Peritubular cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB013072 Enhanced NA Yes 6800000 "Cluster 75: Ovary - Mixed function" "Cluster 33: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 3 "CAB013072: " "unprognostic (3.27e-3)" "unprognostic (1.31e-1)" "unprognostic (6.29e-2)" "unprognostic (3.40e-2)" "unprognostic (3.95e-2)" "unprognostic (5.19e-2)" "unprognostic (4.42e-2)" "unprognostic (4.73e-2)" "unprognostic (2.02e-1)" "potential prognostic unfavorable (9.36e-4)" "unprognostic (1.47e-2)" "unprognostic (4.12e-2)" "potential prognostic unfavorable (3.40e-6)" "unprognostic (2.63e-2)" "unprognostic (1.91e-1)" "unprognostic (3.32e-1)" "unprognostic (3.03e-3)" "unprognostic (2.37e-1)" "unprognostic (4.41e-1)" "unprognostic (7.82e-3)" "potential prognostic unfavorable (1.36e-4)" "unprognostic (5.88e-2)" "unprognostic (1.33e-2)" "unprognostic (4.07e-1)" "unprognostic (2.00e-1)" "unprognostic (5.69e-3)" "unprognostic (5.86e-2)" "potential prognostic unfavorable (3.10e-4)" "unprognostic (9.66e-3)" "unprognostic (1.31e-1)" "unprognostic (1.42e-1)" CDH12 "Br-cadherin, CDHB" ENSG00000154162 "Cadherin 12" P55289 5 21750673-22853344 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "retina: 10.8" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 564.5;Brain inhibitory neurons: 808.6;Choroid plexus epithelial cells: 968.9;Corticotrophs: 466.2;Gonadotrophs: 2384.7;Other brain neurons: 701.2;Retinal amacrine cells: 890.6;Retinal bipolar cells: 1681.4;Retinal ganglion cells: 378.6;Rod photoreceptor cells: 996.3;Thyrotrophs: 1658.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Kidney Chromophobe (TCGA): 2.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 3.2;thyroid cancer: 2.6" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Thyrotropes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029325 Uncertain Uncertain Vesicles NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 1 Vesicles "HPA029325: " "unprognostic (9.95e-2)" "unprognostic (1.73e-2)" "unprognostic (1.26e-1)" "unprognostic (2.22e-2)" "unprognostic (1.70e-2)" "unprognostic (6.37e-2)" CDH13 CDHH ENSG00000140945 "Cadherin 13" P55290 16 82626965-83800640 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 140.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 363.9;Brain inhibitory neurons: 343.2;Cardiomyocytes: 1834.5;Myonuclei: 2264.9;Myosatellite cells: 612.5;Oligodendrocyte progenitor cells: 596.9;Salivary myoepithelial cells: 366.3;Thymic myoid cells: 1325.6;Vascular endothelial cells: 361.9" "Cell type enhanced" "Detected in all" "midbrain-derived inhibitory: 1191.2" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 35.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 4.3" "Group enriched" "Detected in many" 5 "granulocytes: 1.4;monocytes: 4.3" "Cancer enhanced" "Detected in many" "Brain cancer: 66.5;testis cancer: 95.3" "Adipose visceral - Endothelial cells, Lung - Fibroblasts_1, Pituitary gland - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001380, CAB025863" Enhanced Supported "Plasma membrane" "Intracellular and membrane" "Cell adhesion" NA NA 160000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 14: Neurons - Synaptic function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 3 "Plasma membrane" "CAB025863: , HPA001380: " "unprognostic (1.26e-1)" "potential prognostic unfavorable (9.77e-4)" "unprognostic (2.46e-1)" "unprognostic (2.64e-2)" "unprognostic (4.60e-1)" "unprognostic (9.07e-2)" "unprognostic (1.70e-1)" "unprognostic (1.50e-2)" "unprognostic (6.47e-3)" "unprognostic (2.93e-2)" "validated prognostic favorable (1.93e-9)" "validated prognostic favorable (6.97e-5)" "unprognostic (6.80e-3)" "unprognostic (1.34e-1)" "unprognostic (8.41e-3)" "unprognostic (1.43e-1)" "unprognostic (3.30e-2)" "unprognostic (4.46e-2)" "unprognostic (1.19e-1)" "unprognostic (1.04e-1)" "unprognostic (2.13e-3)" "unprognostic (7.78e-2)" "unprognostic (6.16e-2)" "unprognostic (5.57e-1)" "unprognostic (4.24e-1)" "unprognostic (1.50e-3)" "unprognostic (1.15e-2)" "unprognostic (8.98e-3)" "unprognostic (9.13e-2)" "unprognostic (8.74e-2)" "unprognostic (2.69e-2)" CDH15 "CDH14, CDH3" ENSG00000129910 "Cadherin 15" P55291 16 89171748-89195492 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "brain: 79.7;skeletal muscle: 54.1" "Group enriched" "Detected in some" 7 "Brain excitatory neurons: 23.2;Myonuclei: 90.1;Myosatellite cells: 82.8;Thymic myoid cells: 85.7" "Cell type enriched" "Detected in some" 34 "upper rhombic lip: 63.9" "Cancer enhanced" "Detected in some" "Lung Adenocarcinoma (TCGA): 2.4" "Region enriched" "Detected in many" 14 "cerebellum: 51.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 18 "Sarcoma: 32.4" "Region enriched" "Detected in many" 7 "cerebellum: 15.7" "Region enriched" "Detected in some" 19 "cerebellum: 24.8" "HPA009139, HPA070961" Enhanced Supported Supported "Golgi apparatus,Plasma membrane" NA NA 370000 "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 35: Non-specific - DNA binding" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 5 "Golgi apparatus, Plasma membrane" "HPA009139: , HPA070961: " "unprognostic (5.62e-2)" "unprognostic (2.29e-2)" "unprognostic (1.52e-3)" "unprognostic (1.71e-2)" "unprognostic (5.17e-3)" "unprognostic (3.83e-3)" CDH16 ENSG00000166589 "Cadherin 16" O75309 16 66908122-66918917 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "kidney: 252.2" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 169.5;Endometrial luminal cells: 91.2;Epididymal efferent duct ciliated cells: 45.7;Esophageal suprabasal cells: 54.0;Loop of henle epithelial cells: 114.8;Papillary tip epithelial cells: 38.5;Proximal tubule cells: 88.7;Renal collecting duct intercalated cells: 111.6;Renal collecting duct principal cells: 177.7;Renal connecting tubule cells: 200.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 500.3;Kidney Renal Papillary Cell Carcinoma (TCGA): 226.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 15.9;Kidney cancer: 17.5;Uterine cancer: 9.2" "Testis - Late spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB013526, HPA036260" Enhanced NA NA 170000 "Cluster 72: Kidney - Transmembrane transport" "Cluster 15: Kidney cancer - Membrane components" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 2 "CAB013526: , HPA036260: " "unprognostic (5.11e-1)" "unprognostic (1.75e-1)" "potential prognostic favorable (1.72e-5)" "potential prognostic favorable (8.63e-11)" "unprognostic (2.23e-3)" "unprognostic (1.80e-1)" "unprognostic (8.81e-3)" "unprognostic (1.62e-1)" "unprognostic (5.15e-1)" "unprognostic (1.18e-1)" "unprognostic (2.41e-2)" "unprognostic (7.39e-2)" "unprognostic (2.57e-3)" "unprognostic (1.59e-1)" CDH17 "cadherin, HPT-1" ENSG00000079112 "Cadherin 17" Q12864 8 94127162-94217303 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "intestine: 295.7" "Cell type enhanced" "Detected in some" "Colonocytes: 702.7;Enteric stem cells: 219.3;Enteric transient amplifying cells: 327.1;Enterocytes: 556.2;Gastric progenitor cells: 184.6;Goblet cells: 268.8;Neuroendocrine cells: 293.0;Paneth cells: 139.2;Tuft cells: 219.0" "Low cell type specificity" "Detected in some" "Group enriched" "Detected in many" 7 "Colon Adenocarcinoma (TCGA): 241.8;Rectum Adenocarcinoma (TCGA): 243.5;Stomach Adenocarcinoma (TCGA): 83.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "neutrophil: 14.8" "Lineage enriched" "Detected in single" 18 "granulocytes: 14.8" "Group enriched" "Detected in many" 5 "Bile duct cancer: 61.7;colorectal cancer: 158.4;Gastric cancer: 75.7;pancreatic cancer: 48.9" "Colon - Colon enterocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA023614, HPA023616, CAB025143, HPA026556" Enhanced Supported "Nucleoplasm,Cell Junctions" NA NA 4700000 "Cluster 35: Neutrophils - Protein binding" "Cluster 77: Intestine - Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 1 "Cell Junctions" Nucleoplasm "CAB025143: , HPA023614: , HPA023616: , HPA026556: " "unprognostic (1.59e-1)" "unprognostic (3.13e-2)" "unprognostic (3.89e-2)" "unprognostic (1.53e-1)" "potential prognostic unfavorable (9.37e-4)" "unprognostic (9.73e-2)" "unprognostic (2.67e-3)" "unprognostic (1.02e-1)" "unprognostic (1.31e-2)" "unprognostic (1.68e-3)" "unprognostic (1.25e-1)" "unprognostic (1.62e-1)" "unprognostic (1.19e-1)" "unprognostic (2.35e-1)" "unprognostic (6.41e-2)" "unprognostic (1.25e-1)" "unprognostic (4.46e-2)" "unprognostic (2.59e-1)" "unprognostic (1.01e-1)" "unprognostic (3.89e-2)" CDH18 "CDH14, EY-CADHERIN" ENSG00000145526 "Cadherin 18" Q13634 5 19471296-20575873 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 4.4;brain: 16.4;pituitary gland: 3.9" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 425.5;Brain excitatory neurons: 2128.3;Brain inhibitory neurons: 592.9;Lactotrophs: 675.7;Oligodendrocyte progenitor cells: 324.6;Other brain neurons: 900.2;Retinal amacrine cells: 415.0;Retinal ganglion cells: 668.3;Somatotrophs: 387.9;Thyrotrophs: 559.2" "Cell type enhanced" "Detected in all" "upper rhombic lip: 4848.5" "Cancer enhanced" "Detected in some" "Ovary Serous Cystadenocarcinoma (TCGA): 1.4;Uterine Corpus Endometrial Carcinoma (TCGA): 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal medulla cells, Pituitary gland - Lactotropes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014416 Uncertain "Intracellular and membrane" "Cell adhesion" NA Yes "Cluster 27: Cerebellum - Synaptic function" "Cluster 2: Neurons - Nucleosome" "Cluster 15: Kidney cancer - Membrane components" "Cluster 2: Cerebellar granular cells - Neuronal signaling" "HPA014416: " "unprognostic (6.86e-2)" "unprognostic (3.29e-3)" "unprognostic (1.81e-1)" "unprognostic (5.20e-3)" "unprognostic (3.71e-2)" "potential prognostic unfavorable (3.09e-4)" CDH19 CDH7 ENSG00000071991 "Cadherin 19" Q9H159 18 66501083-66604138 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "blood vessel: 14.1;heart muscle: 35.4;intestine: 18.6" "Cell type enriched" "Detected in some" 8 "Schwann cells: 3711.8" "Group enriched" "Detected in many" 4 "committed oligodendrocyte precursor: 161.2;oligodendrocyte: 250.5" "Cancer enriched" "Detected in some" 22 "Skin Cutaneous Melanoma (TCGA): 30.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Sarcoma: 4.8;skin cancer: 12.4" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056332 Uncertain NA NA 470000 "Cluster 35: Non-specific - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 61: Schwann cells & Melanocytes - Mixed function" "HPA056332: " "unprognostic (3.38e-2)" "unprognostic (1.92e-2)" "unprognostic (1.89e-1)" "unprognostic (1.14e-1)" "unprognostic (1.21e-1)" "unprognostic (2.45e-1)" "unprognostic (1.11e-1)" "unprognostic (2.84e-1)" CDH2 "CD325, CDHN, NCAD" ENSG00000170558 "Cadherin 2" P19022 18 27932879-28177946 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cardiomyopathy, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 183.5" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 850.4;Astrocytes: 308.9;Brain excitatory neurons: 291.5;Cardiomyocytes: 1145.4;Cone photoreceptor cells: 714.2;Ependymal cells: 382.0;Müller glia: 385.2;Oligodendrocyte progenitor cells: 309.6;Pituicytes/FSCs: 475.1;Pituitary stem cells: 548.3;Rod photoreceptor cells: 510.7;Sertoli cells: 734.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 82.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 1.7;neutrophil: 1.3" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.7" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Prostate - Smooth muscle cells, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000141, CAB018580, HPA058574, CAB078686, CAB080169" Enhanced Supported "Plasma membrane,Cell Junctions" NA NA 71000000 "Cluster 35: Neutrophils - Protein binding" "Cluster 35: Non-specific - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 30 "Plasma membrane" "Cell Junctions" "CAB000141: , CAB018580: , CAB078686: , CAB080169: , HPA058574: " "unprognostic (2.90e-1)" "unprognostic (1.34e-1)" "unprognostic (7.28e-2)" "unprognostic (2.13e-2)" "unprognostic (1.19e-2)" "unprognostic (2.48e-1)" "unprognostic (2.32e-1)" "unprognostic (2.66e-2)" "unprognostic (7.64e-2)" "potential prognostic favorable (7.16e-5)" "unprognostic (2.92e-3)" "unprognostic (5.18e-2)" "unprognostic (4.40e-2)" "unprognostic (1.11e-2)" "unprognostic (2.64e-2)" "unprognostic (7.69e-2)" "unprognostic (2.48e-2)" "unprognostic (7.27e-2)" "unprognostic (4.31e-2)" "unprognostic (1.22e-1)" "unprognostic (2.90e-2)" "unprognostic (3.81e-2)" "unprognostic (7.90e-2)" "unprognostic (1.71e-1)" "unprognostic (1.08e-3)" "unprognostic (5.44e-3)" "unprognostic (9.80e-2)" "unprognostic (1.48e-1)" "unprognostic (4.22e-2)" CDH20 "Cdh7, CDH7L3" ENSG00000101542 "Cadherin 20" Q9HBT6 18 61333430-61555779 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 17.3;retina: 10.2;tongue: 22.4" "Cell type enhanced" "Detected in many" "Astrocytes: 2068.4;Bergmann glia: 2109.9;Corticotrophs: 394.8;Müller glia: 308.7;Oligodendrocyte progenitor cells: 1063.5;Oligodendrocytes: 1120.2;Retinal bipolar cells: 1298.5;Thymic myoid cells: 1651.9" "Cell type enhanced" "Detected in all" "astrocyte: 2335.3;Bergmann glia: 2215.0;oligodendrocyte: 1518.0" "Cancer enriched" "Detected in single" 15 "Glioblastoma Multiforme (TCGA): 10.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 23 "basophil: 2.3" "Lineage enriched" "Detected in single" 24 "granulocytes: 2.3" "Not detected" "Not detected" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Pituitary gland - Corticotropes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 21000 "Cluster 3: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "unprognostic (2.50e-1)" "potential prognostic favorable (4.44e-5)" CDH22 "C20orf25, dJ998H6.1" ENSG00000149654 "Cadherin 22" Q9UJ99 20 46173739-46308498 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "brain: 44.9" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 28.6;Brain excitatory neurons: 97.7;Brain inhibitory neurons: 36.3;Cone photoreceptor cells: 37.3;Corticotrophs: 55.5;Early spermatids: 91.6;Late primary spermatocytes: 30.7;Late spermatids: 54.8;Pancreatic islet cells: 29.3;Respiratory ionocytes: 45.7;Retinal amacrine cells: 48.8;Retinal bipolar cells: 26.0;Salivary ionocytes: 77.1;Thymic myoid cells: 54.4" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 197.5;upper rhombic lip: 203.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lung cancer: 1.1" "Adrenal gland - Adrenal medulla cells, Heart muscle - Cardiomyocytes, Pancreas - Beta cells, Pituitary gland - Corticotropes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012164, HPA012715" Uncertain Supported NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 2: Neurons - Nucleosome" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 2: Cerebellar granular cells - Neuronal signaling" "HPA012164: , HPA012715: " "unprognostic (7.74e-2)" "unprognostic (4.65e-2)" "unprognostic (5.35e-2)" "unprognostic (2.11e-3)" "unprognostic (7.43e-2)" "potential prognostic unfavorable (4.74e-4)" "unprognostic (5.53e-3)" "unprognostic (1.26e-1)" "unprognostic (6.50e-2)" CDH23 "CDHR23, DFNB12, USH1D" ENSG00000107736 "Cadherin related 23" Q9H251 10 71396920-71815947 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Hearing, Sensory transduction, Vision" "Deafness, Disease variant, Non-syndromic deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 34.8" "Cell type enhanced" "Detected in many" "Adipocytes: 172.1;Cardiomyocytes: 255.9;cDC: 140.0;Early spermatids: 99.6;Epicardial cells: 229.7;Late spermatids: 100.4;Müller glia: 443.6;Neutrophils: 107.8;Sertoli cells: 119.2" "Cell type enhanced" "Detected in all" "endothelial cell: 195.7;fibroblast: 113.8;lower rhombic lip: 147.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 26.8;non-classical monocyte: 38.2" "Lineage enriched" "Detected in many" 4 "monocytes: 38.2" "Cancer enhanced" "Detected in many" "Bone cancer: 9.7" "Adipose subcutaneous - Adipocytes (Subcutaneous), Testis - Sertoli cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA017232 Approved NA NA 1200000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 64: Non-specific - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 1 "HPA017232: " "potential prognostic favorable (1.95e-4)" "unprognostic (1.70e-1)" "unprognostic (6.99e-2)" "potential prognostic favorable (5.49e-4)" "unprognostic (1.17e-1)" "unprognostic (6.75e-2)" "unprognostic (1.88e-2)" "unprognostic (1.17e-1)" "unprognostic (3.68e-2)" "unprognostic (6.75e-3)" "unprognostic (7.44e-2)" "unprognostic (1.19e-3)" "unprognostic (1.65e-2)" "unprognostic (1.06e-1)" "unprognostic (3.75e-2)" "unprognostic (2.14e-1)" "unprognostic (9.74e-3)" "unprognostic (6.39e-2)" "unprognostic (2.80e-1)" "unprognostic (3.85e-2)" "unprognostic (2.24e-3)" "unprognostic (1.42e-2)" "unprognostic (1.26e-1)" "unprognostic (3.93e-3)" CDH24 CDH11L ENSG00000139880 "Cadherin 24" Q86UP0 14 23047062-23057538 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 10.6;Astrocytes: 14.4;Bergmann glia: 12.7;Oligodendrocyte progenitor cells: 7.7;Retinal amacrine cells: 47.6;Tuft cells: 11.5;Vascular endothelial cells: 11.6" "Cell type enhanced" "Detected in many" "deep-layer corticothalamic and 6b: 19.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074551 Approved Vesicles,Cytosol NA NA "Cluster 64: Non-specific - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" Cytosol Vesicles "HPA074551: " "unprognostic (1.31e-1)" "unprognostic (2.39e-1)" "unprognostic (8.49e-2)" "unprognostic (1.37e-1)" "unprognostic (6.89e-2)" "unprognostic (4.72e-2)" "unprognostic (2.18e-1)" "unprognostic (5.32e-3)" "unprognostic (1.05e-1)" "unprognostic (1.24e-2)" "potential prognostic favorable (7.39e-4)" "unprognostic (2.28e-2)" "unprognostic (4.23e-3)" "unprognostic (1.18e-1)" "potential prognostic unfavorable (7.07e-4)" "unprognostic (4.50e-3)" "unprognostic (9.44e-3)" "unprognostic (1.05e-2)" "unprognostic (1.68e-1)" "unprognostic (3.56e-3)" "unprognostic (6.79e-2)" "unprognostic (3.81e-2)" "unprognostic (4.22e-2)" "unprognostic (8.04e-2)" "unprognostic (2.93e-1)" "unprognostic (2.06e-2)" "unprognostic (2.31e-2)" "unprognostic (8.77e-2)" "unprognostic (2.28e-1)" "unprognostic (5.04e-1)" CDH26 VR20 ENSG00000124215 "Cadherin 26" Q8IXH8 20 59958423-60034011 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "prostate: 7.5" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 59.0;Prostatic glandular cells: 72.3;Prostatic hillock cells: 72.7;Respiratory basal cells: 209.8;Respiratory ciliated cells: 75.3;Respiratory deuterosomal cells: 188.7;Respiratory secretory cells: 205.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 8.9" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in some" "HPA015722, HPA047578" Uncertain Supported "Plasma membrane,Microtubules" NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 66: Non-specific - Mitochondria" "Cluster 38: Secretory epithelial cells - Exocrine secretion" "Plasma membrane" Microtubules "HPA015722: , HPA047578: " "unprognostic (2.66e-1)" "unprognostic (4.07e-2)" "unprognostic (1.79e-3)" "unprognostic (3.88e-2)" "unprognostic (2.11e-3)" "potential prognostic favorable (3.80e-5)" "unprognostic (3.86e-2)" "unprognostic (1.88e-1)" "unprognostic (2.81e-1)" "unprognostic (5.63e-3)" "unprognostic (1.51e-2)" "unprognostic (2.39e-2)" CDH3 "CDHP, PCAD" ENSG00000062038 "Cadherin 3" P22223 16 68636189-68727468 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Sensory transduction, Vision" "Disease variant, Ectodermal dysplasia, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 51.8;ovary: 32.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 297.9;Choroid plexus epithelial cells: 127.2;Esophageal basal cells: 202.2;Granulosa cells: 350.3;Melanocytes: 242.5;Ocular epithelial cells: 148.7;Respiratory basal cells: 361.2;Retinal pigment epithelial cells: 264.3;Salivary basal cells: 274.7;Salivary myoepithelial cells: 319.8;Suprabasal keratinocytes: 142.2" "Cell type enriched" "Detected in many" 4 "choroid plexus epithelial cell: 123.0" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 12 "choroid plexus: 100.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 157.4" "Adipose visceral - Mesothelial cells, Spleen - Fibroblasts_1" "Region enhanced" "Detected in single" "olfactory bulb: 1.7" "Low region specificity" "Detected in all" "HPA001767, CAB002487, HPA002974" Enhanced Supported "Plasma membrane,Cell Junctions" NA NA 1800000 "Cluster 44: Bone marrow - Nuclear processes" "Cluster 36: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 26: Keratinocytes - Keratinization" 5 "Plasma membrane, Cell Junctions" "CAB002487: , HPA001767: , HPA002974: " "unprognostic (6.93e-3)" "unprognostic (2.18e-1)" "unprognostic (3.26e-1)" "unprognostic (1.03e-2)" "unprognostic (6.62e-2)" "unprognostic (1.27e-2)" "unprognostic (1.04e-1)" "unprognostic (3.91e-2)" "unprognostic (1.17e-2)" "unprognostic (2.08e-2)" "unprognostic (6.92e-3)" "potential prognostic unfavorable (7.77e-4)" "unprognostic (1.41e-1)" "unprognostic (2.75e-2)" "unprognostic (8.83e-2)" "unprognostic (1.11e-2)" "unprognostic (4.34e-2)" "unprognostic (1.62e-2)" "unprognostic (6.46e-2)" "unprognostic (1.63e-3)" "unprognostic (1.01e-2)" "unprognostic (3.13e-2)" "unprognostic (2.88e-1)" "unprognostic (9.37e-2)" "unprognostic (1.31e-1)" "unprognostic (1.49e-1)" "unprognostic (4.73e-1)" "unprognostic (3.62e-3)" "unprognostic (1.46e-2)" CDH4 R-CAD ENSG00000179242 "Cadherin 4" P55283 20 61252261-61940617 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 12.7;lymphoid tissue: 3.4;ovary: 5.9;skeletal muscle: 3.5" "Cell type enhanced" "Detected in many" "Astrocytes: 217.7;Bergmann glia: 322.4;Brain excitatory neurons: 97.3;Brain inhibitory neurons: 166.8;Ependymal cells: 107.7;Müller glia: 180.8;Myosatellite cells: 569.7;Oligodendrocyte progenitor cells: 181.5;Other brain neurons: 168.5;Retinal amacrine cells: 196.5;Retinal ganglion cells: 92.7;Retinal horizontal cells: 174.3" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Glioblastoma Multiforme (TCGA): 6.1;Kidney Renal Clear Cell Carcinoma (TCGA): 3.8;Kidney Renal Papillary Cell Carcinoma (TCGA): 1.9;Thyroid Carcinoma (TCGA): 1.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 9.6" "Minor Salivary Gland - Smooth muscle cells, Skin - Keratinocyte (granular), Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015613 Supported "Plasma membrane" NA NA 59000 "Cluster 78: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 72: Neuronal - Signal transduction" "Cluster 35: Neurons - Synaptic function & neurogenesis" 2 "Plasma membrane" "HPA015613: " "unprognostic (1.80e-2)" "unprognostic (3.71e-2)" "potential prognostic favorable (1.64e-4)" "unprognostic (2.26e-2)" "unprognostic (3.77e-3)" "unprognostic (2.17e-1)" CDH5 "7B4, CD144" ENSG00000179776 "Cadherin 5" P33151 16 66366622-66404784 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 221.7" "Cell type enhanced" "Detected in some" "Early spermatids: 49.3;Extravillous trophoblasts: 69.0;Kupffer cells: 101.5;Late spermatids: 143.2;Lymphatic endothelial cells: 168.1;Migrating cytotrophoblasts: 47.0;Syncytiotrophoblasts: 126.4;Vascular endothelial cells: 243.7" "Cell type enriched" "Detected in some" 4 "endothelial cell: 186.4" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 64.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "ovarian cancer: 12.0;pancreatic cancer: 9.6;Rhabdoid: 12.8" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Lung - Endothelial cells, Minor Salivary Gland - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Stomach - Endothelial cells, Thyroid gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB028366, HPA075875" Approved Supported "Nucleoplasm,Nuclear membrane,Plasma membrane" NA NA 960000000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 19 "Plasma membrane" "Nucleoplasm, Nuclear membrane" "CAB028366: , HPA075875: " "unprognostic (9.32e-2)" "unprognostic (1.51e-1)" "unprognostic (1.01e-1)" "unprognostic (1.68e-2)" "unprognostic (8.62e-2)" "unprognostic (3.66e-1)" "unprognostic (9.58e-2)" "unprognostic (5.26e-2)" "unprognostic (6.52e-3)" "unprognostic (1.55e-1)" "validated prognostic favorable (1.37e-7)" "validated prognostic favorable (9.91e-4)" "potential prognostic unfavorable (9.22e-5)" "unprognostic (1.37e-1)" "unprognostic (8.39e-3)" "unprognostic (1.59e-1)" "unprognostic (2.09e-1)" "unprognostic (2.55e-2)" "unprognostic (1.95e-1)" "unprognostic (8.25e-2)" "unprognostic (5.76e-2)" "unprognostic (4.29e-2)" "unprognostic (1.25e-1)" "unprognostic (1.07e-1)" "unprognostic (2.05e-2)" "unprognostic (1.19e-1)" "unprognostic (2.12e-1)" "unprognostic (6.53e-3)" "unprognostic (9.63e-2)" "unprognostic (1.07e-1)" "unprognostic (1.16e-2)" CDH6 ENSG00000113361 "Cadherin 6" P55285 5 31193686-31329146 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 12.2;kidney: 13.8" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 71.3;Cholangiocytes: 101.7;Epididymal efferent duct absorptive cells: 102.8;Erythrocyte progenitors: 159.5;Megakaryocyte progenitors: 112.3;Oligodendrocyte progenitor cells: 66.6;Pericytes: 213.6;Pituicytes/FSCs: 113.4;Proximal tubule cells: 418.8;Schwann cells: 76.1;Vascular smooth muscle cells: 221.5" "Cell type enhanced" "Detected in many" "pericyte: 1000.4;vascular associated smooth muscle cell: 631.5" "Group enriched" "Detected in many" 7 "Kidney Renal Clear Cell Carcinoma (TCGA): 63.9;Kidney Renal Papillary Cell Carcinoma (TCGA): 79.9;Ovary Serous Cystadenocarcinoma (TCGA): 33.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 53.6;ovarian cancer: 81.5;Uterine cancer: 44.9" "Breast - Endothelial cells, Prostate - Endothelial cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA007047, HPA007403, HPA007456, CAB025274" Enhanced Supported "Plasma membrane,Cell Junctions" NA NA 16000000 "Cluster 72: Kidney - Transmembrane transport" "Cluster 38: Sub-cortical - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 88: Proximal tubular cells - Transmembrane transport" 1 "Plasma membrane, Cell Junctions" "CAB025274: , HPA007047: , HPA007403: , HPA007456: " "unprognostic (1.07e-1)" "unprognostic (3.08e-2)" "unprognostic (4.47e-1)" "unprognostic (1.56e-2)" "unprognostic (9.49e-2)" "unprognostic (4.81e-2)" "unprognostic (2.68e-2)" "unprognostic (2.09e-3)" "unprognostic (2.12e-2)" "unprognostic (2.57e-1)" "potential prognostic favorable (2.60e-5)" "unprognostic (6.26e-3)" "unprognostic (1.05e-3)" "unprognostic (2.02e-1)" "unprognostic (1.99e-1)" "unprognostic (6.91e-2)" "unprognostic (9.86e-2)" "unprognostic (1.52e-2)" "unprognostic (3.62e-2)" "unprognostic (3.50e-1)" "unprognostic (1.28e-1)" "unprognostic (1.56e-1)" "unprognostic (6.71e-2)" "unprognostic (1.44e-1)" "unprognostic (3.97e-1)" "potential prognostic unfavorable (8.87e-5)" "unprognostic (7.69e-2)" "unprognostic (2.04e-1)" "unprognostic (7.48e-2)" CDH7 ENSG00000081138 "Cadherin 7" Q9ULB5 18 65750252-65890337 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 4.1;retina: 3.4" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 114.5;Brain inhibitory neurons: 112.3;Corticotrophs: 210.8;Hematopoietic stem cells: 109.7;Müller glia: 63.3;Other brain neurons: 69.1;Retinal amacrine cells: 116.1;Retinal ganglion cells: 135.2" "Cell type enhanced" "Detected in many" "lower rhombic lip: 689.0" "Cancer enhanced" "Detected in single" "Prostate Adenocarcinoma (TCGA): 1.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 3.3;Sarcoma: 3.3" "Pituitary gland - Corticotropes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061419 Supported NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 49: Hindbrain - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 109: Neurons - Neuronal signaling" 1 "HPA061419: " "unprognostic (1.28e-1)" "unprognostic (1.20e-1)" "unprognostic (3.63e-1)" CDH8 ENSG00000150394 "Cadherin 8" P55286 16 61647242-62037035 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 16.0;seminal vesicle: 4.7" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 362.9;Brain inhibitory neurons: 479.3;Gonadotrophs: 83.8;Oligodendrocyte progenitor cells: 64.2;Oligodendrocytes: 163.7;Other brain neurons: 326.1;Retinal amacrine cells: 83.7;Retinal bipolar cells: 71.5" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 3.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 9.8;Rhabdoid: 14.1" "Pituitary gland - Gonadotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014908, HPA076441" Approved Approved "Plasma membrane" NA NA 110000 "Cluster 73: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 35: Neurons - Synaptic function & neurogenesis" 5 "Plasma membrane" "HPA014908: , HPA076441: " "unprognostic (8.22e-2)" "unprognostic (3.82e-2)" "unprognostic (4.84e-2)" "potential prognostic favorable (4.36e-6)" "unprognostic (3.59e-2)" "unprognostic (9.92e-2)" "unprognostic (1.52e-1)" "unprognostic (2.84e-2)" "unprognostic (1.63e-1)" CDH9 ENSG00000113100 "Cadherin 9" Q9ULB4 5 26880597-27121150 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.5;kidney: 5.4" "Group enriched" "Detected in some" 6 "Brain excitatory neurons: 278.0;Brain inhibitory neurons: 343.0;Other brain neurons: 206.3;Proximal tubule cells: 357.4" "Cell type enhanced" "Detected in all" "hippocampal dentate gyrus: 1333.8;MGE interneuron: 1041.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 5.0" "Group enriched" "Detected in many" 5 "B-cells: 2.6;granulocytes: 5.0" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA007167 Approved Approved "Golgi apparatus" NA NA 560000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 35: Neurons - Synaptic function & neurogenesis" 1 "Golgi apparatus" "HPA007167: " "unprognostic (2.97e-1)" "unprognostic (2.99e-2)" "unprognostic (1.08e-2)" "unprognostic (1.07e-2)" "unprognostic (1.01e-2)" "unprognostic (2.90e-1)" "unprognostic (1.30e-1)" "unprognostic (2.73e-1)" CDHR1 "CORD15, KIAA1775, PCDH21, RP65" ENSG00000148600 "Cadherin related family member 1" Q96JP9 10 84194537-84219621 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" Receptor "Cone-rod dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "retina: 291.2;skin 1: 202.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 66.7;Colonocytes: 65.7;Cone photoreceptor cells: 358.1;Enteric stem cells: 84.7;Enteric transient amplifying cells: 47.2;Goblet cells: 53.2;Paneth cells: 54.1;Retinal pigment epithelial cells: 42.6;Rod photoreceptor cells: 301.3;Suprabasal keratinocytes: 59.7" "Cell type enhanced" "Detected in many" "deep-layer near-projecting: 33.6" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 20.4;Rectum Adenocarcinoma (TCGA): 24.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 12 "NK-cell: 7.5" "Lineage enriched" "Detected in single" 12 "NK-cells: 7.5" "Cancer enhanced" "Detected in many" "colorectal cancer: 17.9" "Adipose visceral - T-cells, Breast - T-cells, Colon - Colon enterocytes, Liver - NK-cells (Liver), Minor Salivary Gland - Minor salivary gland basal cells, Pituitary gland - Corticotropes, Skin - Keratinocyte (other), Thyroid gland - T-cells" "Region enriched" "Detected in many" 21 "olfactory bulb: 333.1" "Low region specificity" "Detected in all" "HPA010795, HPA036819" Enhanced Approved "Golgi apparatus" "Intracellular and membrane" Receptor NA NA 190000 "Cluster 15: NK-cells - Unknown function" "Cluster 42: Retina - Visual perception" "Cluster 23: Choroid plexus - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 79: Photoreceptor cells - Phototransduction" 1 "Golgi apparatus" "HPA010795: , HPA036819: " "unprognostic (2.58e-2)" "unprognostic (1.06e-2)" "unprognostic (4.03e-1)" "unprognostic (9.84e-3)" "unprognostic (1.10e-1)" "potential prognostic favorable (2.04e-5)" "unprognostic (4.04e-2)" "unprognostic (9.02e-2)" "unprognostic (1.29e-1)" "unprognostic (3.80e-2)" "unprognostic (2.00e-1)" "unprognostic (2.58e-1)" "unprognostic (3.46e-1)" "unprognostic (1.04e-1)" "potential prognostic favorable (6.03e-5)" "unprognostic (2.86e-2)" "unprognostic (1.19e-1)" "unprognostic (2.32e-1)" "unprognostic (1.91e-1)" "unprognostic (6.89e-2)" CDHR2 "FLJ20124, FLJ20383, PC-LKC, PCDH24, PCLKC" ENSG00000074276 "Cadherin related family member 2" Q9BYE9 5 176542511-176595974 "Plasma proteins, Predicted membrane proteins" "Cell adhesion, Differentiation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "intestine: 253.8" "Group enriched" "Detected in many" 4 "Enterocytes: 1082.5;Late spermatids: 1182.2" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 27.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "colorectal cancer: 4.1;Gastric cancer: 5.9;liver cancer: 3.9;pancreatic cancer: 9.6" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells, Testis - Late spermatids" "Region enriched" "Detected in single" 6 "hypothalamus: 2.2" "Low region specificity" "Detected in all" "HPA012569, HPA017053" Enhanced NA NA 24000000 "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 1: Enterocytes - Absorption and Digestion" 4 "HPA012569: , HPA017053: " "unprognostic (5.76e-2)" "unprognostic (9.42e-2)" "validated prognostic favorable (2.11e-4)" "validated prognostic favorable (1.23e-4)" "unprognostic (2.05e-2)" "unprognostic (7.19e-2)" "unprognostic (1.48e-2)" "unprognostic (7.23e-2)" "unprognostic (2.64e-3)" "unprognostic (7.32e-3)" "unprognostic (1.01e-1)" "unprognostic (7.60e-2)" "unprognostic (1.53e-1)" CDHR3 "CDH28, FLJ23834, FLJ44366" ENSG00000128536 "Cadherin related family member 3" Q6ZTQ4 7 105876796-106036432 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" Asthma "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "choroid plexus: 34.2;fallopian tube: 102.3" "Cell type enhanced" "Detected in many" "Astrocytes: 359.4;Choroid plexus epithelial cells: 412.0;Endometrial ciliated cells: 818.8;Ependymal cells: 489.5;Epididymal efferent duct ciliated cells: 337.0;Fallopian tube ciliated cells: 1065.9;Neuroendocrine cells: 619.2;Proximal tubule cells: 357.0;Respiratory ciliated cells: 2226.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 8.9" "Region enhanced" "Detected in all" "choroid plexus: 100.8" "Immune cell enhanced" "Detected in some" "memory B-cell: 2.0;naive B-cell: 2.9" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in some" "lymphoma: 4.9" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Skeletal muscle - Fibroblasts, Testis - Late spermatids" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "midbrain: 16.1" HPA011218 Supported NA NA "Cluster 34: B-cells - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" 6 "HPA011218: " "unprognostic (1.05e-3)" "unprognostic (8.94e-2)" "unprognostic (6.04e-2)" "unprognostic (5.35e-1)" "unprognostic (2.29e-1)" "unprognostic (1.50e-1)" "unprognostic (2.52e-2)" "unprognostic (5.99e-3)" "unprognostic (1.12e-1)" "unprognostic (1.32e-3)" "unprognostic (2.94e-2)" "unprognostic (7.92e-2)" "unprognostic (1.70e-1)" "unprognostic (9.46e-2)" "unprognostic (8.82e-2)" "unprognostic (2.98e-2)" "unprognostic (5.97e-2)" "unprognostic (6.09e-2)" "unprognostic (4.20e-2)" "unprognostic (2.28e-1)" "unprognostic (9.02e-2)" "unprognostic (8.50e-2)" CDHR4 "CDH29, VLLR9392" ENSG00000187492 "Cadherin related family member 4" A6H8M9 3 49790732-49799873 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "fallopian tube: 55.8" "Group enriched" "Detected in some" 4 "Endometrial ciliated cells: 160.0;Epididymal efferent duct ciliated cells: 197.3;Fallopian tube ciliated cells: 180.1;Respiratory ciliated cells: 253.0" "Cell type enriched" "Detected in single" 101 "ependymal cell: 40.1" "Cancer enriched" "Detected in many" 5 "Uterine Corpus Endometrial Carcinoma (TCGA): 17.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 2.0" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Adipose subcutaneous - Adipose progenitor cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - Fibroblasts, Skeletal muscle - Fibroblasts, Testis - Early spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA076277 Enhanced "Intracellular and membrane" "Cell adhesion" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 107: Ciliated cells - Cilia assembly & function" "HPA076277: " "unprognostic (2.68e-3)" "unprognostic (2.58e-1)" "unprognostic (1.23e-2)" "unprognostic (2.40e-1)" "unprognostic (1.84e-1)" "unprognostic (1.64e-1)" "unprognostic (2.95e-1)" "unprognostic (1.91e-1)" "unprognostic (5.33e-2)" "unprognostic (5.92e-2)" "unprognostic (1.22e-1)" "unprognostic (1.94e-2)" "unprognostic (3.01e-2)" CDHR5 "FLJ20219, MU-PCDH, MUCDHL, MUPCDH" ENSG00000099834 "Cadherin related family member 5" Q9HBB8 11 616577-626078 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 296.9;liver: 129.1" "Group enriched" "Detected in some" 4 "Colonocytes: 119.8;Enterocytes: 47.0;Proximal tubule cells: 92.0;Tuft cells: 34.6" "Cell type enriched" "Detected in single" 12 "choroid plexus epithelial cell: 9.3" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 23.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 3.7" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Stomach - Gastric mucous cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA009081, HPA009173, CAB025004" Enhanced NA NA 16000000 "Cluster 77: Intestine - Digestion" "Cluster 6: Non-specific - Immune response" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" "CAB025004: , HPA009081: , HPA009173: " "unprognostic (4.70e-2)" "unprognostic (5.93e-2)" "validated prognostic favorable (1.59e-5)" "validated prognostic favorable (3.35e-5)" "potential prognostic favorable (9.70e-4)" "unprognostic (1.93e-1)" "unprognostic (2.32e-3)" "unprognostic (7.53e-3)" "unprognostic (1.47e-1)" "unprognostic (3.14e-1)" "unprognostic (5.98e-2)" "unprognostic (1.74e-1)" "unprognostic (1.77e-2)" CDIN1 "C15orf41, FLJ22851, HH114, MGC11326" ENSG00000186073 "CDAN1 interacting nuclease 1" Q9Y2V0 15 36579626-36810248 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Congenital dyserythropoietic anemia, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "heart muscle: 73.6;tongue: 32.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 1644.5;Myonuclei: 292.3;Thymic myoid cells: 422.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061023 Uncertain Approved Nucleoplasm NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 35: Non-specific - Mixed function" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 5 Nucleoplasm "HPA061023: " "unprognostic (1.20e-1)" "unprognostic (1.16e-1)" "unprognostic (2.32e-1)" "unprognostic (1.43e-1)" "unprognostic (4.53e-2)" "unprognostic (5.03e-2)" "unprognostic (3.77e-2)" "unprognostic (6.41e-2)" "unprognostic (2.04e-2)" "unprognostic (3.51e-3)" "unprognostic (6.02e-2)" "unprognostic (6.41e-3)" "unprognostic (2.10e-2)" "potential prognostic unfavorable (6.97e-5)" "unprognostic (4.05e-2)" "unprognostic (3.48e-2)" "unprognostic (7.41e-2)" "unprognostic (4.70e-1)" "unprognostic (2.38e-1)" "potential prognostic unfavorable (5.10e-4)" "unprognostic (2.16e-1)" "unprognostic (1.14e-1)" "unprognostic (9.89e-2)" "unprognostic (4.28e-2)" "unprognostic (5.84e-2)" "unprognostic (1.78e-1)" "unprognostic (1.22e-1)" "potential prognostic unfavorable (4.78e-5)" "unprognostic (1.14e-1)" CDIP1 "C16orf5, CDIP, LITAFL" ENSG00000089486 "Cell death inducing p53 target 1" Q9H305 16 4510669-4538828 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 159.5" "Cell type enhanced" "Detected in many" "Astrocytes: 48.2;Bergmann glia: 33.5;Brain excitatory neurons: 38.0;Brain inhibitory neurons: 38.0;Choroid plexus epithelial cells: 33.7;Other brain neurons: 45.3;Proximal tubule cells: 31.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Minor Salivary Gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049352 Approved Supported Nucleoplasm,Centrosome NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 78: Brain - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 102: Non-specific - Mixed function" 10 Centrosome Nucleoplasm "HPA049352: " "unprognostic (1.18e-1)" "unprognostic (1.85e-1)" "unprognostic (9.73e-2)" "unprognostic (2.37e-2)" "unprognostic (1.48e-1)" "unprognostic (4.70e-2)" "unprognostic (8.02e-2)" "unprognostic (5.34e-2)" "unprognostic (9.55e-2)" "potential prognostic favorable (2.61e-5)" "unprognostic (2.99e-3)" "unprognostic (6.74e-2)" "unprognostic (1.95e-1)" "unprognostic (2.65e-2)" "unprognostic (2.65e-1)" "unprognostic (4.75e-3)" "unprognostic (2.65e-1)" "unprognostic (1.65e-2)" "unprognostic (1.11e-1)" "potential prognostic favorable (5.40e-5)" "unprognostic (1.57e-2)" "unprognostic (2.46e-2)" "unprognostic (4.45e-1)" "unprognostic (1.87e-2)" "unprognostic (3.58e-1)" "potential prognostic unfavorable (4.85e-4)" "unprognostic (3.40e-2)" "unprognostic (1.17e-1)" "unprognostic (1.09e-1)" CDIPT "PIS, PIS1" ENSG00000103502 "CDP-diacylglycerol--inositol 3-phosphatidyltransferase" O14735 16 29858357-29863414 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 146.5;Extravillous trophoblasts: 167.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056597 Enhanced Approved "Nucleoplasm,Nuclear membrane,Plasma membrane" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 64: Non-specific - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 52 "Nucleoplasm, Nuclear membrane, Plasma membrane" "HPA056597: " "unprognostic (6.10e-2)" "unprognostic (2.39e-2)" "unprognostic (7.23e-2)" "unprognostic (3.83e-2)" "unprognostic (1.35e-2)" "unprognostic (3.10e-2)" "unprognostic (3.41e-2)" "unprognostic (2.32e-2)" "unprognostic (1.97e-2)" "unprognostic (4.90e-2)" "unprognostic (3.98e-3)" "unprognostic (8.29e-2)" "unprognostic (3.72e-2)" "unprognostic (8.59e-2)" "unprognostic (3.25e-3)" "unprognostic (1.12e-1)" "unprognostic (9.91e-2)" "unprognostic (1.94e-1)" "unprognostic (2.44e-1)" "unprognostic (3.07e-2)" "unprognostic (3.21e-1)" "unprognostic (7.26e-2)" "unprognostic (6.69e-2)" "unprognostic (2.89e-1)" "unprognostic (1.61e-1)" "unprognostic (5.28e-2)" "unprognostic (8.41e-2)" "unprognostic (1.56e-2)" "unprognostic (1.81e-1)" "unprognostic (1.91e-1)" "unprognostic (9.69e-2)" CDK1 "CDC2, CDC28A" ENSG00000170312 "Cyclin dependent kinase 1" P06493 10 60778331-60794852 "Cancer-related genes, Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Apoptosis, Biological rhythms, Cell cycle, Cell division, Host-virus interaction, Mitosis" "Host cell receptor for virus entry, Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 50.2;lymphoid tissue: 68.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 83.8;Differentiating spermatogonia: 65.2;Early primary spermatocytes: 67.7;Enteric transient amplifying cells: 76.4;Erythrocyte progenitors: 125.8;Esophageal basal cells: 88.1;Extravillous trophoblasts: 161.3;Gastric progenitor cells: 144.8;Hofbauer cells: 97.9;Late primary spermatocytes: 189.7;Megakaryocyte progenitors: 97.8;Migrating cytotrophoblasts: 143.4;Monocyte progenitors: 159.0;Oocytes: 138.2;Respiratory deuterosomal cells: 70.5" "Group enriched" "Detected in some" 4 "endothelial cell: 4.4;leukocyte: 1.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "NK-cell: 3.3;T-reg: 3.4" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Pituitary gland - Somatotropes, Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003387, CAB003799, CAB079974" Enhanced Supported "Nucleoplasm,Cytosol,Acrosome,Perinuclear theca,Connecting piece,Flagellar centriole" NA Yes 44000 "Cluster 16: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 12: Non-specific - Vasculature" "Cluster 52: Non-specific - Mitochondria" "Cluster 27: Non-specific - Cell proliferation" 168 "Nucleoplasm, Cytosol" "Acrosome, Perinuclear theca, Connecting piece, Flagellar centriole" "CAB003799: , CAB079974: , HPA003387: " "unprognostic (1.34e-2)" "unprognostic (4.52e-2)" "unprognostic (1.93e-1)" "unprognostic (3.95e-2)" "unprognostic (1.94e-1)" "unprognostic (4.15e-2)" "unprognostic (2.29e-1)" "unprognostic (3.41e-2)" "unprognostic (6.71e-2)" "potential prognostic unfavorable (5.73e-5)" "validated prognostic unfavorable (1.67e-4)" "validated prognostic unfavorable (1.04e-5)" "potential prognostic unfavorable (4.02e-13)" "validated prognostic unfavorable (2.85e-7)" "validated prognostic unfavorable (4.81e-7)" "potential prognostic unfavorable (3.19e-6)" "unprognostic (1.72e-3)" "unprognostic (6.79e-2)" "unprognostic (3.36e-2)" "unprognostic (4.50e-1)" "unprognostic (6.05e-2)" "validated prognostic unfavorable (2.06e-6)" "validated prognostic unfavorable (2.44e-4)" "unprognostic (8.87e-2)" "unprognostic (9.32e-2)" "unprognostic (6.75e-2)" "unprognostic (5.51e-3)" "unprognostic (1.17e-1)" "unprognostic (3.69e-1)" "unprognostic (1.47e-1)" "unprognostic (2.15e-1)" CDK10 PISSLRE ENSG00000185324 "Cyclin dependent kinase 10" Q15131 16 89680737-89696354 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubule cells: 102.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007451 Uncertain NA Yes "Cluster 33: Non-specific - ATP binding" "Cluster 70: Non-specific - Protein processing" "Cluster 48: Non-specific - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 9 "HPA007451: " "unprognostic (3.51e-1)" "unprognostic (1.14e-1)" "unprognostic (4.21e-2)" "unprognostic (1.63e-1)" "potential prognostic unfavorable (9.92e-4)" "unprognostic (1.59e-1)" "unprognostic (1.58e-1)" "unprognostic (2.78e-3)" "unprognostic (4.89e-2)" "unprognostic (2.38e-2)" "potential prognostic favorable (8.98e-6)" "unprognostic (1.73e-2)" "potential prognostic favorable (2.08e-7)" "unprognostic (5.25e-3)" "unprognostic (1.11e-1)" "unprognostic (7.51e-2)" "unprognostic (1.38e-1)" "potential prognostic unfavorable (9.42e-4)" "unprognostic (2.40e-3)" "unprognostic (9.08e-2)" "potential prognostic favorable (9.96e-4)" "unprognostic (8.45e-3)" "unprognostic (2.22e-1)" "unprognostic (9.94e-2)" "unprognostic (3.19e-1)" "unprognostic (9.63e-2)" "unprognostic (3.23e-1)" "unprognostic (1.70e-1)" "unprognostic (3.06e-1)" "unprognostic (1.64e-1)" "unprognostic (9.79e-2)" CDK11A "CDC2L2, CDC2L3, CDK11-p110, CDK11-p46, CDK11-p58, p58GTA, PITSLRE" ENSG00000008128 "Cyclin dependent kinase 11A" Q9UQ88 1 1702379-1724357 "Enzymes, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 48.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 85.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "CAB010467, HPA025061, HPA073626" Supported Supported "Nuclear speckles,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 47: Leukemia - Hemostasis" "Cluster 102: Non-specific - Mixed function" 22 "Nuclear speckles" Cytosol "CAB010467: , HPA025061: , HPA073626: " "unprognostic (1.74e-2)" "unprognostic (1.61e-1)" "unprognostic (9.94e-2)" "unprognostic (3.04e-2)" "unprognostic (3.05e-1)" "unprognostic (2.52e-2)" "unprognostic (1.54e-1)" "unprognostic (1.05e-1)" "unprognostic (2.80e-1)" "unprognostic (7.37e-2)" "unprognostic (4.61e-2)" "unprognostic (3.29e-1)" "unprognostic (1.87e-1)" "potential prognostic unfavorable (8.73e-5)" "unprognostic (3.42e-2)" "unprognostic (1.43e-1)" "unprognostic (1.45e-1)" "unprognostic (2.06e-2)" "unprognostic (6.91e-2)" "unprognostic (1.89e-2)" "unprognostic (5.15e-3)" "unprognostic (2.02e-1)" "unprognostic (3.49e-2)" "unprognostic (2.74e-1)" "unprognostic (8.32e-2)" "unprognostic (1.24e-1)" "unprognostic (7.32e-3)" "unprognostic (1.04e-1)" "unprognostic (6.64e-2)" "unprognostic (6.58e-2)" "unprognostic (1.19e-1)" CDK11B "CDC2L1, CDK11-p110, CDK11-p46, CDK11-p58" ENSG00000248333 "Cyclin dependent kinase 11B" P21127 1 1635225-1659012 "Enzymes, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 216.0;Early primary spermatocytes: 162.1;Neutrophils: 170.7;Oocytes: 156.6;Undifferentiated spermatogonia: 160.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA025061, HPA073626" Approved Approved "Nuclear speckles" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 24: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 37: Non-specific - mRNA processing" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 30 "Nuclear speckles" "HPA025061: , HPA073626: " "potential prognostic unfavorable (5.98e-4)" "unprognostic (1.01e-2)" "unprognostic (2.50e-1)" "unprognostic (1.25e-2)" "unprognostic (7.15e-2)" "unprognostic (4.18e-1)" "unprognostic (9.76e-3)" "unprognostic (3.39e-1)" "unprognostic (4.88e-3)" "unprognostic (3.12e-1)" "unprognostic (1.56e-2)" "unprognostic (7.68e-2)" "unprognostic (1.14e-1)" "potential prognostic unfavorable (4.39e-5)" "unprognostic (1.80e-3)" "unprognostic (7.18e-2)" "unprognostic (4.01e-2)" "unprognostic (2.56e-1)" "unprognostic (9.80e-2)" "unprognostic (2.01e-1)" "unprognostic (6.60e-2)" "unprognostic (1.46e-1)" "unprognostic (5.22e-2)" "unprognostic (1.08e-1)" "unprognostic (3.13e-2)" "unprognostic (1.58e-3)" "unprognostic (1.10e-1)" "unprognostic (8.99e-2)" "unprognostic (1.21e-1)" "unprognostic (3.66e-1)" "unprognostic (1.59e-2)" CDK12 "CRK7, CRKR, CRKRS, KIAA0904" ENSG00000167258 "Cyclin dependent kinase 12" Q9NYV4 17 39461486-39564907 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008038, HPA073305" Supported Enhanced "Nucleoplasm,Nuclear speckles" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Breast cancer - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 17 "Nucleoplasm, Nuclear speckles" "HPA008038: , HPA073305: " "unprognostic (3.19e-2)" "unprognostic (1.27e-1)" "unprognostic (4.94e-1)" "unprognostic (1.90e-2)" "unprognostic (1.75e-1)" "unprognostic (2.87e-1)" "unprognostic (1.21e-1)" "unprognostic (3.46e-2)" "unprognostic (2.57e-1)" "unprognostic (1.02e-3)" "potential prognostic favorable (2.96e-4)" "unprognostic (2.64e-3)" "unprognostic (6.41e-2)" "unprognostic (5.91e-3)" "unprognostic (1.01e-1)" "unprognostic (1.17e-1)" "unprognostic (5.63e-3)" "unprognostic (1.16e-1)" "unprognostic (8.27e-3)" "unprognostic (4.09e-3)" "unprognostic (1.11e-1)" "unprognostic (2.82e-3)" "unprognostic (1.19e-3)" "unprognostic (2.13e-1)" "unprognostic (4.45e-3)" "potential prognostic favorable (5.45e-5)" "unprognostic (2.94e-2)" "unprognostic (1.36e-1)" "unprognostic (2.85e-1)" "unprognostic (1.03e-2)" "unprognostic (1.64e-1)" CDK13 "CDC2L, CDC2L5, CHED, KIAA1791" ENSG00000065883 "Cyclin dependent kinase 13" Q14004 7 39950121-40099580 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059241 Uncertain Supported "Nuclear speckles,Golgi apparatus,Cytosol" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 61: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 67: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 20 "Nuclear speckles" "Golgi apparatus, Cytosol" "HPA059241: " "unprognostic (8.41e-2)" "unprognostic (1.07e-1)" "unprognostic (8.20e-2)" "unprognostic (8.58e-3)" "unprognostic (2.38e-1)" "unprognostic (1.75e-1)" "unprognostic (9.50e-2)" "unprognostic (7.99e-2)" "unprognostic (6.00e-2)" "unprognostic (2.45e-3)" "unprognostic (3.47e-3)" "unprognostic (5.61e-3)" "unprognostic (1.85e-1)" "unprognostic (4.41e-3)" "unprognostic (2.22e-1)" "unprognostic (1.19e-1)" "unprognostic (2.27e-2)" "unprognostic (2.71e-1)" "unprognostic (3.54e-1)" "unprognostic (1.14e-2)" "unprognostic (1.56e-1)" "unprognostic (1.47e-1)" "unprognostic (1.35e-2)" "unprognostic (8.81e-2)" "unprognostic (5.73e-2)" "unprognostic (9.83e-2)" "unprognostic (1.85e-1)" "unprognostic (1.66e-1)" "unprognostic (1.98e-1)" "unprognostic (6.03e-3)" "unprognostic (5.52e-2)" CDK14 "PFTAIRE1, PFTK1" ENSG00000058091 "Cyclin dependent kinase 14" O94921 7 90466424-91210590 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 796.5;Mesothelial cells: 719.4;Neutrophil progenitors: 725.7;Neutrophils: 1014.8;Plasma cells: 738.2;Retinal horizontal cells: 1302.2;Somatotrophs: 713.1;Transitional alveolar cells: 785.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "basophil: 9.1;memory B-cell: 8.5;naive B-cell: 4.8;neutrophil: 4.8" "Group enriched" "Detected in many" 10 "B-cells: 8.5;granulocytes: 9.1" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015267 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 27: Cerebellum - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 27 Nucleoplasm Cytosol "HPA015267: " "unprognostic (1.23e-3)" "unprognostic (2.18e-3)" "unprognostic (1.18e-1)" "unprognostic (1.52e-1)" "unprognostic (2.16e-2)" "unprognostic (2.22e-1)" "unprognostic (1.53e-1)" "unprognostic (1.97e-2)" "unprognostic (2.55e-1)" "unprognostic (1.39e-2)" "potential prognostic favorable (1.99e-6)" "unprognostic (5.10e-2)" "unprognostic (1.08e-1)" "unprognostic (8.19e-2)" "potential prognostic unfavorable (3.89e-6)" "unprognostic (7.87e-2)" "unprognostic (8.95e-2)" "unprognostic (2.49e-1)" "unprognostic (4.65e-2)" "unprognostic (2.45e-2)" "unprognostic (2.14e-2)" "unprognostic (4.47e-3)" "unprognostic (4.13e-3)" "unprognostic (9.46e-2)" "unprognostic (1.44e-2)" "unprognostic (3.41e-1)" "unprognostic (1.33e-1)" "potential prognostic unfavorable (7.32e-4)" "unprognostic (2.47e-1)" "unprognostic (1.21e-1)" "unprognostic (3.69e-1)" CDK15 "ALS2CR7, PFTAIRE2, PFTK2" ENSG00000138395 "Cyclin dependent kinase 15" Q96Q40 2 201790461-201895550 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "epididymis: 14.4;ovary: 4.7" "Cell type enriched" "Detected in some" 5 "Mast cells: 392.4" "Cell type enhanced" "Detected in many" "vascular associated smooth muscle cell: 26.0" "Cancer enhanced" "Detected in single" "Skin Cutaneous Melanoma (TCGA): 1.1" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 28 "basophil: 1.9;eosinophil: 3.7" "Lineage enriched" "Detected in single" 37 "granulocytes: 3.7" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 9.3;Kidney cancer: 8.5" "Adipose subcutaneous - Mast cells, Adrenal gland - Fibroblasts, Breast - Fibroblasts, Colon - Mast cells, Kidney - Fibroblasts, Lung - Mast cells, Minor Salivary Gland - Mast cells, Pituitary gland - Fibroblasts, Prostate - Fibroblasts, Skin - Mast cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA015786 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 22: Epididymis - Mixed function" "Cluster 35: Non-specific - DNA binding" "Cluster 49: HMC-1 - Innate immune response" "Cluster 58: Mast cells - Allergic inflammatory responses" 7 "Nucleoplasm, Golgi apparatus" "HPA015786: " "unprognostic (2.33e-3)" "unprognostic (3.33e-2)" CDK16 "FLJ16665, PCTAIRE, PCTAIRE1, PCTGAIRE, PCTK1" ENSG00000102225 "Cyclin dependent kinase 16" Q00536 X 47217860-47229997 "Enzymes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 157.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000974, HPA001366, CAB016535" Approved Supported "Plasma membrane,Microtubules,Cytosol" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 65: Non-specific - Cell growth & division" 35 "Microtubules, Cytosol" "Plasma membrane" "CAB016535: , HPA000974: , HPA001366: " "unprognostic (2.67e-2)" "unprognostic (1.72e-3)" "unprognostic (1.95e-1)" "unprognostic (1.05e-1)" "unprognostic (1.42e-1)" "unprognostic (4.29e-3)" "unprognostic (1.84e-2)" "unprognostic (7.22e-2)" "unprognostic (4.82e-3)" "unprognostic (3.71e-2)" "unprognostic (2.00e-1)" "unprognostic (2.71e-2)" "unprognostic (1.39e-1)" "potential prognostic unfavorable (4.41e-6)" "unprognostic (1.71e-3)" "unprognostic (5.28e-3)" "potential prognostic unfavorable (2.79e-5)" "unprognostic (2.48e-1)" "unprognostic (9.15e-3)" "unprognostic (2.60e-2)" "unprognostic (1.18e-1)" "unprognostic (1.88e-2)" "unprognostic (2.74e-1)" "unprognostic (9.14e-2)" "unprognostic (1.22e-1)" "unprognostic (2.08e-1)" "unprognostic (2.02e-1)" "unprognostic (7.47e-2)" "unprognostic (1.74e-1)" "unprognostic (6.09e-2)" "unprognostic (4.52e-2)" CDK17 "PCTAIRE2, PCTK2" ENSG00000059758 "Cyclin dependent kinase 17" Q00537 12 96278261-96400480 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Mast cells: 390.7;Neutrophil progenitors: 380.4;Neutrophils: 393.8;NK-cells: 522.5;T-cells: 381.5;Vascular endothelial cells: 383.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Skeletal muscle - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015325 Approved Approved Nucleoplasm,Cytosol Yes No "Cluster 5: Non-specific - Cell proliferation" "Cluster 73: Brain - Neuronal signaling" "Cluster 34: Non-specific - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 19 "Nucleoplasm, Cytosol" "HPA015325: " "unprognostic (5.48e-2)" "unprognostic (3.24e-1)" "unprognostic (4.93e-1)" "unprognostic (2.13e-1)" "unprognostic (1.47e-1)" "unprognostic (1.04e-1)" "unprognostic (2.84e-1)" "unprognostic (4.05e-1)" "unprognostic (5.46e-3)" "unprognostic (4.93e-2)" "unprognostic (1.14e-3)" "unprognostic (3.20e-3)" "unprognostic (2.30e-2)" "unprognostic (2.13e-2)" "unprognostic (2.04e-1)" "unprognostic (4.57e-2)" "unprognostic (2.30e-2)" "unprognostic (1.01e-2)" "unprognostic (7.66e-2)" "unprognostic (8.43e-3)" "unprognostic (1.54e-2)" "unprognostic (2.97e-1)" "unprognostic (4.58e-3)" "unprognostic (2.19e-1)" "unprognostic (1.82e-1)" "unprognostic (2.43e-2)" "unprognostic (2.79e-2)" "unprognostic (1.21e-2)" "unprognostic (3.98e-1)" "unprognostic (5.08e-3)" "unprognostic (1.65e-2)" CDK18 "PCTAIRE3, PCTK3" ENSG00000117266 "Cyclin dependent kinase 18" Q07002 1 205504596-205532793 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "brain: 367.7;heart muscle: 116.7" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 552.9" "Group enriched" "Detected in all" 8 "committed oligodendrocyte precursor: 407.0;oligodendrocyte: 755.9" "Cancer enriched" "Detected in all" 5 "Kidney Renal Clear Cell Carcinoma (TCGA): 145.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045429 Approved Approved "Actin filaments,Mitotic spindle,Primary cilium,Basal body,Cytosol" Yes No "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 15: Kidney cancer - Membrane components" "Cluster 80: Oligodendrocytes - Myelination" 58 "Actin filaments, Cytosol" "Mitotic spindle, Primary cilium, Basal body" "HPA045429: " "unprognostic (2.00e-1)" "unprognostic (1.20e-1)" "unprognostic (1.28e-1)" "unprognostic (4.01e-2)" "unprognostic (1.57e-1)" "unprognostic (2.57e-1)" "unprognostic (2.40e-3)" "unprognostic (9.00e-2)" "unprognostic (1.57e-1)" "unprognostic (4.90e-2)" "potential prognostic favorable (1.27e-6)" "unprognostic (1.54e-3)" "unprognostic (2.33e-2)" "unprognostic (6.24e-3)" "unprognostic (1.05e-1)" "unprognostic (9.30e-2)" "unprognostic (3.92e-1)" "unprognostic (8.37e-3)" "unprognostic (9.64e-2)" "unprognostic (2.00e-2)" "unprognostic (1.21e-2)" "unprognostic (4.53e-2)" "unprognostic (1.13e-1)" "unprognostic (2.06e-1)" "unprognostic (7.85e-2)" "unprognostic (3.34e-1)" "unprognostic (3.70e-1)" "unprognostic (2.42e-2)" "unprognostic (2.13e-1)" "unprognostic (4.02e-2)" "unprognostic (1.80e-1)" CDK19 "bA346C16.3, CDC2L6, CDK11, KIAA1028" ENSG00000155111 "Cyclin dependent kinase 19" Q9BWU1 6 110609978-110815958 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 473.1;Neutrophils: 820.7;Oligodendrocytes: 726.4;Prostatic glandular cells: 598.1" "Cell type enhanced" "Detected in all" "oligodendrocyte: 951.2" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 39.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007053, HPA007062" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 60: Prostate cancer - Unknown function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 108 Cytosol Nucleoplasm "HPA007053: , HPA007062: " "unprognostic (6.85e-2)" "unprognostic (9.77e-3)" "unprognostic (2.62e-2)" "unprognostic (1.19e-2)" "unprognostic (1.99e-1)" "unprognostic (3.26e-2)" "unprognostic (1.50e-1)" "unprognostic (1.22e-2)" "unprognostic (1.35e-2)" "potential prognostic unfavorable (4.76e-5)" "validated prognostic favorable (3.40e-7)" "validated prognostic favorable (3.52e-5)" "unprognostic (2.19e-1)" "potential prognostic unfavorable (1.49e-4)" "unprognostic (1.34e-1)" "unprognostic (1.47e-1)" "unprognostic (1.01e-3)" "unprognostic (2.65e-2)" "unprognostic (7.93e-2)" "potential prognostic unfavorable (1.55e-4)" "unprognostic (7.94e-3)" "unprognostic (1.33e-1)" "unprognostic (1.01e-1)" "unprognostic (3.21e-1)" "unprognostic (1.24e-2)" "unprognostic (2.89e-1)" "unprognostic (1.25e-1)" "unprognostic (4.26e-1)" "unprognostic (1.89e-1)" "unprognostic (4.39e-2)" "unprognostic (2.79e-1)" CDK2 ENSG00000123374 "Cyclin dependent kinase 2" P24941 12 55966781-55972789 "Cancer-related genes, Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Meiosis, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 120.3;Extravillous trophoblasts: 99.4;Melanocytes: 141.9;Migrating cytotrophoblasts: 145.1;Syncytiotrophoblasts: 245.2" "Cell type enhanced" "Detected in some" "endothelial cell: 13.0;vascular associated smooth muscle cell: 8.0" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 224.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "skin cancer: 288.4" "Heart muscle - Endothelial cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013115, HPA066915" Enhanced Approved "Nucleoplasm,Plasma membrane,Centrosome,Basal body,Calyx" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 49: Non-specific - Transcription" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 230 Nucleoplasm "Plasma membrane, Centrosome, Basal body, Calyx" "CAB013115: , HPA066915: " "unprognostic (1.96e-1)" "unprognostic (4.53e-2)" "unprognostic (8.14e-2)" "unprognostic (5.12e-2)" "unprognostic (3.46e-1)" "unprognostic (3.45e-1)" "unprognostic (2.06e-1)" "unprognostic (3.78e-2)" "unprognostic (2.17e-2)" "potential prognostic unfavorable (1.54e-4)" "unprognostic (3.60e-2)" "unprognostic (6.12e-3)" "unprognostic (3.97e-2)" "validated prognostic unfavorable (6.18e-5)" "validated prognostic unfavorable (6.43e-4)" "potential prognostic unfavorable (3.58e-4)" "unprognostic (2.39e-3)" "unprognostic (1.53e-1)" "unprognostic (1.47e-1)" "unprognostic (2.68e-1)" "unprognostic (9.39e-2)" "unprognostic (1.01e-3)" "unprognostic (5.62e-2)" "potential prognostic unfavorable (8.81e-5)" "unprognostic (9.58e-2)" "unprognostic (3.17e-2)" "unprognostic (2.91e-1)" "unprognostic (8.60e-2)" "unprognostic (2.80e-1)" "unprognostic (1.43e-1)" "unprognostic (1.23e-1)" CDK20 "CCRK, p42, PNQALRE" ENSG00000156345 "Cyclin dependent kinase 20" Q8IZL9 9 87966441-87974753 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 19.0;Fallopian tube ciliated cells: 23.5;Late primary spermatocytes: 45.5;Oocytes: 18.4;Respiratory ciliated cells: 18.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 3.6" "Group enriched" "Detected in many" 8 "NK-cells: 3.6;T-cells: 2.3" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA007666, HPA027379, HPA027401" Enhanced Supported "Nucleoplasm,Golgi apparatus,Connecting piece,Mid piece,Principal piece,End piece" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" 13 Nucleoplasm "Golgi apparatus, Connecting piece, Mid piece, Principal piece, End piece" "HPA007666: , HPA027379: , HPA027401: " "unprognostic (2.17e-2)" "unprognostic (1.97e-1)" "unprognostic (1.71e-1)" "unprognostic (3.29e-1)" "unprognostic (2.47e-1)" "unprognostic (4.86e-2)" "unprognostic (6.68e-2)" "unprognostic (1.73e-2)" "unprognostic (7.55e-3)" "unprognostic (3.53e-2)" "validated prognostic favorable (8.86e-11)" "validated prognostic favorable (9.86e-4)" "potential prognostic favorable (1.91e-4)" "unprognostic (1.65e-3)" "unprognostic (8.71e-2)" "unprognostic (3.89e-2)" "unprognostic (7.04e-2)" "unprognostic (2.84e-3)" "unprognostic (2.17e-1)" "unprognostic (3.30e-1)" "unprognostic (7.59e-3)" "unprognostic (5.01e-2)" "unprognostic (1.94e-1)" "unprognostic (8.52e-2)" "unprognostic (2.88e-2)" "unprognostic (1.42e-1)" "unprognostic (3.08e-1)" "unprognostic (1.22e-2)" "unprognostic (1.22e-1)" "unprognostic (7.37e-2)" "unprognostic (1.16e-2)" CDK2AP1 "doc-1, DOC1, DORC1, p12DOC-1, ST19" ENSG00000111328 "Cyclin dependent kinase 2 associated protein 1" O14519 12 123250112-123272334 "Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 431.1" "Cell type enhanced" "Detected in many" "Late spermatids: 264.1;Megakaryocytes: 568.7;Platelets: 307.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 44.5;intermediate monocyte: 153.2;myeloid DC: 52.6;non-classical monocyte: 176.5" "Group enriched" "Detected in many" 5 "dendritic cells: 52.6;monocytes: 176.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019377, HPA057648, HPA068833" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 47: Platelets - Hemostasis" 49 Nucleoplasm Cytosol "CAB019377: , HPA057648: , HPA068833: " "unprognostic (8.31e-2)" "unprognostic (9.40e-2)" "unprognostic (3.86e-2)" "unprognostic (1.41e-1)" "unprognostic (2.17e-1)" "unprognostic (2.94e-3)" "unprognostic (8.71e-2)" "unprognostic (2.20e-1)" "unprognostic (2.42e-1)" "potential prognostic unfavorable (5.85e-4)" "unprognostic (5.95e-3)" "unprognostic (1.78e-2)" "unprognostic (1.97e-3)" "unprognostic (6.99e-3)" "potential prognostic unfavorable (4.68e-4)" "unprognostic (4.05e-3)" "unprognostic (3.57e-2)" "unprognostic (1.14e-2)" "unprognostic (2.21e-1)" "unprognostic (9.55e-2)" "unprognostic (7.39e-2)" "unprognostic (5.92e-3)" "unprognostic (1.53e-1)" "unprognostic (4.30e-1)" "unprognostic (1.11e-2)" "unprognostic (5.32e-2)" "unprognostic (2.27e-1)" "unprognostic (3.95e-2)" "unprognostic (5.98e-2)" "unprognostic (2.84e-1)" "unprognostic (1.60e-1)" CDK2AP2 "DOC-1R, p14" ENSG00000167797 "Cyclin dependent kinase 2 associated protein 2" O75956 11 67506497-67508649 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal efferent duct absorptive cells: 256.3;Epididymal principal cells: 903.5;Extravillous trophoblasts: 242.3;Megakaryocytes: 278.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038872, HPA047599" Uncertain Approved Nucleoplasm NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 19: Astrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" 6 Nucleoplasm "HPA038872: , HPA047599: " "unprognostic (1.95e-1)" "unprognostic (5.95e-2)" "unprognostic (1.09e-1)" "unprognostic (3.58e-1)" "unprognostic (7.50e-2)" "unprognostic (8.49e-3)" "unprognostic (4.07e-3)" "unprognostic (6.72e-2)" "unprognostic (6.24e-3)" "unprognostic (5.06e-2)" "unprognostic (1.71e-2)" "unprognostic (2.34e-2)" "unprognostic (1.46e-1)" "potential prognostic unfavorable (2.45e-4)" "unprognostic (1.64e-1)" "unprognostic (2.38e-1)" "unprognostic (1.49e-1)" "unprognostic (7.68e-2)" "unprognostic (1.32e-1)" "unprognostic (5.91e-3)" "unprognostic (1.26e-1)" "unprognostic (7.23e-3)" "unprognostic (6.71e-2)" "unprognostic (3.29e-1)" "unprognostic (1.79e-2)" "unprognostic (4.16e-2)" "unprognostic (3.09e-1)" "unprognostic (4.38e-2)" "unprognostic (1.63e-1)" "unprognostic (1.04e-1)" "unprognostic (8.19e-2)" CDK3 ENSG00000250506 "Cyclin dependent kinase 3" Q00526 17 76000855-76005999 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 7.0;Bergmann glia: 5.9;Choroid plexus epithelial cells: 3.6;Distal convoluted tubule cells: 7.5;Loop of henle epithelial cells: 6.2;Microglia: 5.5;Oligodendrocyte progenitor cells: 4.8;Oligodendrocytes: 6.1;Other brain neurons: 3.1;Papillary tip epithelial cells: 6.7;Podocytes: 9.8;Proximal tubule cells: 12.4;Renal collecting duct intercalated cells: 6.7;Renal collecting duct principal cells: 4.0;Renal connecting tubule cells: 8.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA007420 Uncertain Approved Cytosol NA NA "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 11: White matter - Signal transduction" "Cluster 56: Non-specific - Sensory perception" "Cluster 102: Non-specific - Mixed function" 40 Cytosol "HPA007420: " "unprognostic (1.68e-2)" "unprognostic (1.17e-1)" "unprognostic (1.71e-1)" "unprognostic (1.85e-1)" "unprognostic (1.21e-1)" "unprognostic (7.43e-2)" "unprognostic (1.06e-2)" "unprognostic (1.26e-2)" "unprognostic (1.60e-3)" "unprognostic (4.79e-3)" "potential prognostic unfavorable (2.58e-6)" "unprognostic (3.58e-2)" "unprognostic (4.54e-2)" "unprognostic (3.40e-2)" "unprognostic (2.37e-2)" "unprognostic (7.80e-2)" "unprognostic (5.20e-2)" "unprognostic (2.06e-1)" "unprognostic (1.20e-3)" "unprognostic (7.45e-2)" "potential prognostic favorable (2.29e-5)" "potential prognostic favorable (5.20e-5)" "unprognostic (3.21e-3)" "unprognostic (1.08e-2)" "unprognostic (3.90e-2)" "unprognostic (5.78e-3)" "unprognostic (1.26e-2)" "unprognostic (1.49e-1)" "unprognostic (4.30e-1)" "unprognostic (1.33e-1)" "unprognostic (1.95e-2)" CDK4 PSK-J3 ENSG00000135446 "Cyclin dependent kinase 4" P11802 12 57747727-57756013 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Decidual stromal cells: 194.8;Esophageal basal cells: 181.0;Hofbauer cells: 196.8" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 5 "Glioblastoma Multiforme (TCGA): 998.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006024, CAB013116, CAB069405" Supported Supported "Nucleoplasm,Nuclear membrane,Nucleoli,Cytosol" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 54: Non-specific - Ribosome" "Cluster 25: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 115 "Nucleoplasm, Cytosol" "Nuclear membrane, Nucleoli" "CAB013116: , CAB069405: , HPA006024: " "unprognostic (1.44e-1)" "unprognostic (5.22e-3)" "unprognostic (1.61e-1)" "unprognostic (5.07e-2)" "unprognostic (1.60e-1)" "unprognostic (1.27e-1)" "unprognostic (2.47e-1)" "unprognostic (1.72e-2)" "unprognostic (1.68e-1)" "potential prognostic unfavorable (8.12e-6)" "potential prognostic favorable (8.58e-4)" "unprognostic (2.61e-3)" "potential prognostic unfavorable (5.35e-4)" "validated prognostic unfavorable (3.43e-6)" "validated prognostic unfavorable (2.85e-8)" "unprognostic (2.24e-2)" "potential prognostic unfavorable (3.19e-4)" "unprognostic (9.36e-3)" "unprognostic (1.85e-2)" "unprognostic (5.25e-3)" "unprognostic (1.42e-1)" "unprognostic (1.85e-1)" "unprognostic (3.44e-1)" "unprognostic (3.14e-1)" "unprognostic (1.86e-1)" "unprognostic (1.10e-2)" "unprognostic (2.36e-3)" "unprognostic (2.24e-1)" "unprognostic (1.07e-1)" "unprognostic (2.11e-2)" "unprognostic (6.45e-3)" CDK5 PSSALRE ENSG00000164885 "Cyclin dependent kinase 5" Q00535 7 151053815-151057897 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Biological rhythms, Cell cycle, Cell division, Neurogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Lissencephaly, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 75.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 31.6;Decidual stromal cells: 44.1;Hofbauer cells: 45.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Macrophages" "Low region specificity" "Detected in all" "CAB008909, HPA064535" Enhanced Supported "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 78: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 39: Non-specific - Transcription" "Cluster 98: Neurons - Neurotransmission & signaling" 91 "Nucleoplasm, Plasma membrane" "Cell Junctions" "CAB008909: , HPA064535: " "unprognostic (1.69e-1)" "unprognostic (2.79e-2)" "unprognostic (1.61e-1)" "unprognostic (2.53e-2)" "unprognostic (3.80e-2)" "unprognostic (2.17e-1)" "potential prognostic unfavorable (4.08e-5)" "unprognostic (2.33e-1)" "unprognostic (1.96e-1)" "potential prognostic unfavorable (7.70e-5)" "unprognostic (2.92e-3)" "potential prognostic unfavorable (5.91e-4)" "unprognostic (5.38e-2)" "potential prognostic unfavorable (7.49e-5)" "unprognostic (5.36e-3)" "unprognostic (1.78e-1)" "unprognostic (1.57e-2)" "unprognostic (7.11e-3)" "unprognostic (2.30e-1)" "unprognostic (1.88e-3)" "unprognostic (1.72e-1)" "unprognostic (6.34e-2)" "unprognostic (3.30e-1)" "unprognostic (5.34e-2)" "unprognostic (1.63e-1)" "unprognostic (9.40e-2)" "unprognostic (2.67e-1)" "unprognostic (9.98e-3)" "unprognostic (2.83e-1)" "unprognostic (3.74e-2)" "unprognostic (2.54e-2)" CDK5R1 "Nck5a, p35, p35nck5a" ENSG00000176749 "Cyclin dependent kinase 5 regulatory subunit 1" Q15078 17 32486993-32491253 "Predicted intracellular proteins" "Biological rhythms" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 71.3" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 42.5;Brain inhibitory neurons: 42.9;Cone photoreceptor cells: 16.6;Early spermatids: 21.4;Esophageal apical cells: 27.0;Late spermatids: 26.2;Müller glia: 15.7;Other brain neurons: 42.1;Retinal amacrine cells: 34.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 23.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Colon enteroendocrine cells, Skin - Keratinocyte (granular), Spleen - B-cells (Spleen), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000252 Supported Nucleoplasm,Vesicles NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 109: Neurons - Neuronal signaling" 32 Nucleoplasm Vesicles "HPA000252: " "unprognostic (1.95e-1)" "unprognostic (5.22e-2)" "unprognostic (3.94e-1)" "unprognostic (1.34e-1)" "unprognostic (3.34e-2)" "unprognostic (4.17e-2)" "unprognostic (1.14e-1)" "potential prognostic favorable (5.66e-4)" "unprognostic (3.44e-2)" "unprognostic (1.76e-1)" "unprognostic (1.65e-1)" "unprognostic (5.79e-2)" "unprognostic (1.33e-1)" "unprognostic (3.75e-3)" "potential prognostic unfavorable (5.39e-4)" "unprognostic (4.07e-2)" "unprognostic (4.51e-2)" "unprognostic (4.93e-2)" "unprognostic (4.05e-2)" "unprognostic (2.09e-3)" "unprognostic (1.44e-1)" "unprognostic (2.09e-1)" "unprognostic (1.42e-2)" "unprognostic (2.90e-1)" "unprognostic (2.33e-1)" "unprognostic (3.38e-2)" "unprognostic (6.47e-2)" CDK5R2 "NCK5AI, P39, p39nck5ai" ENSG00000171450 "Cyclin dependent kinase 5 regulatory subunit 2" Q13319 2 218959666-218962155 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "brain: 57.4;pituitary gland: 33.2;retina: 24.4" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 21.3;Brain excitatory neurons: 22.4;Brain inhibitory neurons: 23.4;Cone photoreceptor cells: 20.7;Corticotrophs: 19.8;Lactotrophs: 24.8;Neuroendocrine cells: 25.9;Other brain neurons: 28.6;Pancreatic islet cells: 62.5;Retinal amacrine cells: 16.9;Retinal bipolar cells: 50.1;Retinal ganglion cells: 11.6;Rod photoreceptor cells: 31.9;Somatotrophs: 20.7;Thyrotrophs: 15.4" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 6.5;Pancreatic Adenocarcinoma (TCGA): 3.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "lung cancer: 8.3;Neuroblastoma: 17.4" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Stomach - Gastric enteroendocrine cells, Thyroid gland - Parafollicular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 2 "unprognostic (5.40e-2)" "unprognostic (1.03e-1)" "unprognostic (1.21e-2)" "unprognostic (1.35e-3)" "unprognostic (1.09e-1)" "unprognostic (2.87e-2)" CDK5RAP1 "C20orf34, C42, CGI-05, HSPC167" ENSG00000101391 "CDK5 regulatory subunit associated protein 1" Q96SZ6 20 33358839-33401561 "Enzymes, Predicted intracellular proteins" "tRNA processing" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 109.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051329, HPA055429" Supported Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 79: Photoreceptor cells - Phototransduction" 3 Mitochondria "Nucleoplasm, Cytosol" "HPA051329: , HPA055429: " "unprognostic (9.43e-2)" "unprognostic (2.51e-2)" "unprognostic (1.61e-2)" "unprognostic (9.23e-2)" "unprognostic (3.50e-1)" "unprognostic (2.10e-1)" "unprognostic (3.75e-1)" "unprognostic (6.55e-3)" "unprognostic (8.46e-2)" "unprognostic (6.80e-3)" "unprognostic (1.36e-3)" "unprognostic (1.71e-1)" "unprognostic (2.07e-2)" "potential prognostic unfavorable (1.97e-4)" "unprognostic (2.22e-2)" "unprognostic (2.01e-1)" "unprognostic (6.85e-3)" "unprognostic (5.02e-2)" "unprognostic (2.38e-2)" "unprognostic (9.94e-2)" "unprognostic (4.36e-1)" "unprognostic (3.53e-1)" "potential prognostic unfavorable (7.99e-5)" "unprognostic (2.05e-2)" "unprognostic (1.77e-3)" "unprognostic (9.16e-3)" "unprognostic (1.18e-1)" "unprognostic (1.70e-1)" "unprognostic (7.78e-2)" "unprognostic (6.27e-2)" "unprognostic (7.26e-2)" CDK5RAP2 "C48, CEP215, FLJ10867, MCPH3" ENSG00000136861 "CDK5 regulatory subunit associated protein 2" Q96SN8 9 120388875-120580170 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Calmodulin-binding "Intellectual disability, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 345.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035820, HPA035821, HPA046529, CAB079753" Approved Supported "Cell Junctions,Centrosome,Basal body,Cytosol,Equatorial segment,Mid piece,Principal piece" NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 24: Neutrophils - Innate immunity signal integration" 35 "Centrosome, Basal body" "Cell Junctions, Cytosol, Equatorial segment, Mid piece, Principal piece" "CAB079753: , HPA035820: , HPA035821: , HPA046529: " "unprognostic (1.66e-2)" "unprognostic (3.89e-1)" "unprognostic (2.84e-1)" "unprognostic (4.28e-2)" "unprognostic (2.15e-2)" "unprognostic (1.13e-3)" "unprognostic (2.68e-2)" "unprognostic (2.62e-2)" "unprognostic (1.60e-1)" "unprognostic (2.17e-1)" "potential prognostic favorable (1.56e-4)" "unprognostic (5.64e-3)" "unprognostic (1.62e-1)" "unprognostic (3.98e-3)" "unprognostic (1.54e-1)" "unprognostic (4.55e-2)" "unprognostic (2.99e-3)" "unprognostic (9.58e-2)" "unprognostic (1.75e-2)" "unprognostic (4.62e-2)" "unprognostic (6.49e-2)" "unprognostic (1.69e-1)" "unprognostic (1.65e-2)" "unprognostic (1.01e-1)" "unprognostic (2.48e-1)" "unprognostic (8.99e-2)" "unprognostic (1.48e-1)" "unprognostic (1.51e-1)" "unprognostic (2.35e-1)" "unprognostic (4.05e-2)" "unprognostic (5.61e-2)" CDK5RAP3 "C53, FLJ13660, HSF-27, IC53, LZAP, MST016, OK/SW-cl.114" ENSG00000108465 "CDK5 regulatory subunit associated protein 3" Q96JB5 17 47967810-47981781 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 69.6;Bergmann glia: 65.0;Foveolar cells: 74.6;Gastric chief cells: 47.0;Oligodendrocytes: 48.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022141, HPA022882, HPA027883" Supported Supported Nucleoli,Vesicles,Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 36: Choroid plexus - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 15: Non-specific - Protein processing" 38 Cytosol "Nucleoli, Vesicles" "HPA022141: , HPA022882: , HPA027883: " "unprognostic (2.91e-1)" "unprognostic (3.86e-1)" "unprognostic (1.99e-1)" "unprognostic (1.59e-2)" "unprognostic (8.82e-2)" "unprognostic (3.47e-2)" "unprognostic (2.28e-1)" "unprognostic (1.70e-2)" "unprognostic (1.73e-1)" "unprognostic (1.26e-1)" "unprognostic (2.75e-2)" "unprognostic (2.92e-1)" "unprognostic (3.08e-3)" "unprognostic (1.54e-1)" "unprognostic (5.97e-2)" "unprognostic (1.45e-1)" "unprognostic (2.60e-2)" "unprognostic (3.03e-1)" "unprognostic (1.33e-1)" "unprognostic (1.23e-1)" "unprognostic (1.76e-1)" "unprognostic (1.79e-2)" "unprognostic (1.08e-1)" "unprognostic (9.87e-2)" "unprognostic (8.12e-3)" "unprognostic (1.34e-2)" "unprognostic (1.20e-1)" "unprognostic (1.06e-2)" "unprognostic (9.73e-2)" "unprognostic (1.14e-1)" "unprognostic (1.20e-1)" CDK6 PLSTIRE ENSG00000105810 "Cyclin dependent kinase 6" Q00534 7 92604921-92836573 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 38.3" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 660.2;Hematopoietic stem cells: 1044.2;Megakaryocyte progenitors: 1154.0;Megakaryocyte-Erythroid progenitors: 1460.4;Thymocytes: 1313.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts, Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA002637, CAB004363" Enhanced Supported Nucleoplasm,Cytosol NA NA 8900 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 80: Thymus - Adaptive immune response" "Cluster 11: White matter - Signal transduction" "Cluster 59: Leukemia - T-cell receptor" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 76 Nucleoplasm Cytosol "CAB004363: , HPA002637: " "unprognostic (4.45e-1)" "unprognostic (6.82e-2)" "unprognostic (1.29e-1)" "unprognostic (8.53e-3)" "unprognostic (1.73e-1)" "unprognostic (6.26e-3)" "unprognostic (2.31e-1)" "unprognostic (1.46e-1)" "unprognostic (1.20e-2)" "unprognostic (1.43e-2)" "unprognostic (1.21e-2)" "unprognostic (7.40e-2)" "unprognostic (1.20e-1)" "unprognostic (2.02e-1)" "unprognostic (6.84e-2)" "potential prognostic unfavorable (1.29e-4)" "unprognostic (1.28e-1)" "unprognostic (1.63e-1)" "unprognostic (2.92e-1)" "unprognostic (7.31e-3)" "unprognostic (1.65e-1)" "validated prognostic unfavorable (7.99e-6)" "validated prognostic unfavorable (5.59e-6)" "unprognostic (2.17e-2)" "unprognostic (2.09e-1)" "unprognostic (8.82e-2)" "unprognostic (6.95e-2)" "unprognostic (1.67e-1)" "unprognostic (1.56e-1)" "unprognostic (7.86e-2)" "unprognostic (9.71e-3)" CDK7 "CAK, CAK1, CDKN7, MO15, STK1" ENSG00000134058 "Cyclin dependent kinase 7" P50613 5 69234795-69277430 "Cancer-related genes, Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 108.7;Esophageal apical cells: 142.4;Extravillous trophoblasts: 381.0;Late primary spermatocytes: 101.0;Migrating cytotrophoblasts: 171.8;Oocytes: 175.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004364, HPA007932, HPA008453, CAB079975" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Plasma membrane,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 24: Non-specific - Transcription" "Cluster 23: Choroid plexus - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 96 Nucleoplasm "Nucleoli fibrillar center, Plasma membrane, Cytosol" "CAB004364: , CAB079975: , HPA007932: , HPA008453: " "unprognostic (2.11e-2)" "unprognostic (2.98e-2)" "unprognostic (2.14e-1)" "unprognostic (1.14e-1)" "unprognostic (1.11e-1)" "unprognostic (3.55e-2)" "unprognostic (9.17e-3)" "unprognostic (3.17e-1)" "unprognostic (3.72e-2)" "unprognostic (7.59e-2)" "unprognostic (8.70e-2)" "unprognostic (3.25e-1)" "unprognostic (1.06e-1)" "potential prognostic unfavorable (2.61e-5)" "unprognostic (2.08e-2)" "unprognostic (5.93e-2)" "unprognostic (6.15e-2)" "unprognostic (2.41e-1)" "unprognostic (1.89e-1)" "unprognostic (2.78e-1)" "potential prognostic unfavorable (2.64e-5)" "unprognostic (1.22e-1)" "unprognostic (1.12e-3)" "unprognostic (1.82e-1)" "unprognostic (7.20e-2)" "unprognostic (3.19e-1)" "unprognostic (2.28e-2)" "unprognostic (2.99e-1)" "unprognostic (1.39e-1)" "unprognostic (1.04e-1)" "unprognostic (2.82e-2)" CDK8 K35 ENSG00000132964 "Cyclin dependent kinase 8" P49336 13 26254104-26420982 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Kinase, Repressor, Serine/threonine-protein kinase, Transferase" "Autism spectrum disorder, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Myonuclei: 427.0;Myosatellite cells: 477.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044721 Approved Nucleoplasm NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 17: Intestine - Digestion" "Cluster 35: Non-specific - DNA binding" "Cluster 19: Non-specific - Unknown function" "Cluster 55: Myocytes - Oxidative muscle function" 84 Nucleoplasm "HPA044721: " "unprognostic (3.66e-2)" "unprognostic (2.62e-2)" "unprognostic (2.03e-1)" "unprognostic (1.52e-3)" "unprognostic (6.41e-2)" "unprognostic (3.01e-2)" "unprognostic (1.64e-3)" "unprognostic (9.81e-3)" "unprognostic (2.76e-1)" "unprognostic (2.67e-2)" "validated prognostic favorable (2.53e-6)" "validated prognostic favorable (3.86e-4)" "unprognostic (4.38e-2)" "unprognostic (4.18e-2)" "unprognostic (2.53e-2)" "unprognostic (7.72e-2)" "unprognostic (1.11e-2)" "unprognostic (6.89e-2)" "unprognostic (1.36e-1)" "unprognostic (1.07e-3)" "unprognostic (1.44e-2)" "unprognostic (1.42e-2)" "unprognostic (1.31e-2)" "unprognostic (1.39e-3)" "unprognostic (4.62e-3)" "unprognostic (1.91e-1)" "unprognostic (3.67e-1)" "unprognostic (7.04e-2)" "unprognostic (1.55e-1)" "unprognostic (1.65e-2)" "unprognostic (1.09e-1)" CDK9 "C-2k, CDC2L4, PITALRE, TAK" ENSG00000136807 "Cyclin dependent kinase 9" P50750 9 127785679-127790792 "Disease related genes, Enzymes, Essential proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004216, HPA006738" Supported Approved "Nucleoplasm,Cytoplasmic bodies" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 64: Non-specific - Transcription" "Cluster 29: Forebrain - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 35: Neurons - Synaptic function & neurogenesis" 175 Nucleoplasm "Cytoplasmic bodies" "CAB004216: , HPA006738: " "unprognostic (4.27e-2)" "unprognostic (2.62e-1)" "unprognostic (4.55e-1)" "unprognostic (4.37e-2)" "unprognostic (5.29e-2)" "unprognostic (1.47e-3)" "unprognostic (2.20e-1)" "unprognostic (7.65e-3)" "unprognostic (1.71e-2)" "unprognostic (4.95e-1)" "potential prognostic unfavorable (8.52e-4)" "unprognostic (1.06e-1)" "unprognostic (4.04e-2)" "unprognostic (1.33e-1)" "unprognostic (9.62e-2)" "unprognostic (1.83e-1)" "unprognostic (2.87e-1)" "unprognostic (5.35e-2)" "unprognostic (2.53e-2)" "unprognostic (1.99e-1)" "unprognostic (1.71e-1)" "unprognostic (1.02e-2)" "unprognostic (3.37e-1)" "unprognostic (3.27e-2)" "unprognostic (2.04e-1)" "unprognostic (2.28e-2)" "unprognostic (5.35e-2)" "unprognostic (1.56e-1)" "unprognostic (2.30e-1)" "unprognostic (1.13e-1)" "unprognostic (6.11e-3)" CDKAL1 FLJ20342 ENSG00000145996 "CDK5 regulatory subunit associated protein 1 like 1" Q5VV42 6 20534457-21232404 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "tRNA processing" Transferase "Diabetes mellitus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 65: Non-specific - Unknown function" "Cluster 51: Secretory epithelial cells - Mixed function" 18 "unprognostic (1.29e-1)" "unprognostic (2.27e-1)" "unprognostic (1.99e-3)" "unprognostic (1.27e-1)" "unprognostic (5.52e-1)" "unprognostic (2.82e-1)" "unprognostic (3.57e-1)" "unprognostic (1.56e-3)" "unprognostic (3.31e-2)" "potential prognostic unfavorable (4.87e-4)" "potential prognostic favorable (2.01e-5)" "unprognostic (1.93e-3)" "unprognostic (9.90e-3)" "unprognostic (1.83e-2)" "unprognostic (4.02e-3)" "unprognostic (1.87e-2)" "unprognostic (2.22e-1)" "unprognostic (1.47e-1)" "unprognostic (2.99e-2)" "unprognostic (1.98e-3)" "unprognostic (5.55e-3)" "unprognostic (3.30e-1)" "unprognostic (2.22e-2)" "unprognostic (1.22e-1)" "unprognostic (2.49e-2)" "unprognostic (2.00e-3)" "unprognostic (4.25e-3)" "unprognostic (1.82e-1)" "unprognostic (6.56e-2)" "unprognostic (4.54e-2)" "unprognostic (6.31e-2)" CDKL1 KKIALRE ENSG00000100490 "Cyclin dependent kinase like 1" Q00532 14 50326265-50416461 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fallopian tube ciliated cells: 298.9;Loop of henle epithelial cells: 237.4;Platelets: 179.5;Proximal tubule cells: 165.2;Renal collecting duct intercalated cells: 170.0;Renal collecting duct principal cells: 234.7;Renal connecting tubule cells: 165.8;Respiratory ciliated cells: 295.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059605, HPA065919" Uncertain Enhanced "Nucleoplasm,Vesicles,Flagellar centriole,Mid piece" NA NA "Cluster 32: Basophils - Transcription" "Cluster 75: Ovary - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 6 "Nucleoplasm, Vesicles" "Flagellar centriole, Mid piece" "HPA059605: , HPA065919: " "unprognostic (1.60e-1)" "unprognostic (1.97e-1)" "unprognostic (3.70e-2)" "unprognostic (6.53e-2)" "unprognostic (2.12e-1)" "unprognostic (2.55e-1)" "unprognostic (8.21e-2)" "unprognostic (8.07e-3)" "unprognostic (9.05e-3)" "unprognostic (2.07e-2)" "validated prognostic favorable (5.70e-6)" "validated prognostic favorable (7.05e-5)" "unprognostic (1.37e-1)" "unprognostic (7.08e-2)" "unprognostic (1.78e-1)" "unprognostic (9.81e-3)" "unprognostic (4.66e-2)" "unprognostic (2.23e-1)" "unprognostic (1.06e-1)" "unprognostic (2.12e-1)" "unprognostic (2.71e-1)" "unprognostic (1.09e-1)" "unprognostic (1.24e-1)" "unprognostic (1.59e-1)" "unprognostic (9.45e-2)" "unprognostic (4.31e-2)" "unprognostic (3.88e-2)" "unprognostic (8.85e-2)" "unprognostic (1.84e-1)" "unprognostic (3.43e-2)" "unprognostic (2.64e-1)" CDKL2 "KKIAMRE, P56" ENSG00000138769 "Cyclin dependent kinase like 2" Q92772 4 75576496-75630716 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "retina: 8.9;testis: 10.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 102.6;Choroid plexus epithelial cells: 87.1;Ependymal cells: 58.5;Epididymal efferent duct ciliated cells: 61.7;Late primary spermatocytes: 182.3;Loop of henle epithelial cells: 73.1;Other brain neurons: 60.2;Retinal ganglion cells: 81.1" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Kidney Chromophobe (TCGA): 3.8;Kidney Renal Clear Cell Carcinoma (TCGA): 2.4;Kidney Renal Papillary Cell Carcinoma (TCGA): 4.9;Lung Adenocarcinoma (TCGA): 5.1;Thyroid Carcinoma (TCGA): 3.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Skin - Sebaceous gland cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040672 Approved Nucleoplasm,Centrosome NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 9: Non-specific - Receptor signaling" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 34: Ciliated cells - Cilia assembly & function" "Nucleoplasm, Centrosome" "HPA040672: " "unprognostic (1.49e-1)" "unprognostic (1.99e-2)" "unprognostic (5.14e-1)" "validated prognostic favorable (9.27e-11)" "validated prognostic favorable (1.76e-4)" "unprognostic (3.05e-3)" "potential prognostic favorable (1.29e-4)" "unprognostic (1.88e-1)" "unprognostic (9.34e-2)" "unprognostic (2.03e-1)" CDKL3 NKIAMRE ENSG00000006837 "Cyclin dependent kinase like 3" Q8IVW4 5 134286350-134371047 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 13.7" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 33.6;Early spermatids: 105.1;Late primary spermatocytes: 53.6;Late spermatids: 170.0;Loop of henle epithelial cells: 47.2;Papillary tip epithelial cells: 27.2;Podocytes: 57.0;Proximal tubule cells: 37.4;Renal collecting duct intercalated cells: 18.2;Renal collecting duct principal cells: 32.3;Renal connecting tubule cells: 35.4" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA027751 Uncertain Nucleoplasm,Vesicles NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 67: Testis - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 105: Non-specific - Mixed function" 23 "Nucleoplasm, Vesicles" "HPA027751: " "unprognostic (3.38e-2)" "unprognostic (1.44e-2)" "unprognostic (8.45e-2)" "potential prognostic unfavorable (1.27e-5)" "unprognostic (5.90e-2)" "unprognostic (1.30e-1)" "unprognostic (1.45e-2)" "unprognostic (6.13e-2)" "unprognostic (2.83e-1)" "unprognostic (4.48e-2)" "unprognostic (1.79e-1)" "unprognostic (3.36e-2)" "unprognostic (4.39e-3)" "unprognostic (1.97e-1)" "unprognostic (9.48e-3)" "unprognostic (1.79e-2)" "unprognostic (1.62e-1)" "unprognostic (2.11e-1)" "unprognostic (1.77e-1)" "unprognostic (5.09e-3)" "unprognostic (7.41e-2)" CDKL4 ENSG00000205111 "Cyclin dependent kinase like 4" Q5MAI5 2 39168045-39243983 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "testis: 1.8" "Cell type enhanced" "Detected in many" "Early spermatids: 26.0;Endometrial glandular cells: 72.7;Endometrial luminal cells: 25.4;Epididymal clear cells: 55.1;Late primary spermatocytes: 26.8" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067895 Uncertain NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 51: Secretory epithelial cells - Mixed function" 1 "HPA067895: " "unprognostic (1.80e-1)" "potential prognostic unfavorable (8.52e-4)" CDKL5 "CFAP247, EIEE2, STK9" ENSG00000008086 "Cyclin dependent kinase like 5" O76039 X 18425583-18653629 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 12.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 229.4;Cone photoreceptor cells: 223.6;Neutrophils: 228.0;Retinal horizontal cells: 220.4;Urothelial cells: 329.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 5.7" "Lineage enriched" "Detected in single" 11 "granulocytes: 5.7" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002847, CAB011577" Approved Supported Nucleoplasm NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 1: Neuronal - Visual perception" "Cluster 69: Urothelial cells - Basic cellular functions" 6 Nucleoplasm "CAB011577: , HPA002847: " "unprognostic (2.51e-1)" "unprognostic (2.35e-2)" "unprognostic (2.38e-1)" "unprognostic (1.28e-1)" "unprognostic (4.05e-2)" "unprognostic (2.60e-1)" "unprognostic (1.92e-1)" "unprognostic (1.63e-1)" "unprognostic (9.89e-2)" "unprognostic (1.08e-2)" "potential prognostic favorable (2.18e-6)" "unprognostic (5.49e-2)" "unprognostic (5.73e-2)" "unprognostic (1.96e-1)" "unprognostic (3.55e-2)" "unprognostic (3.70e-1)" "unprognostic (1.54e-2)" "unprognostic (5.37e-2)" "unprognostic (1.30e-2)" "unprognostic (2.32e-1)" "unprognostic (3.07e-1)" "unprognostic (1.11e-1)" "unprognostic (9.51e-2)" "unprognostic (1.81e-1)" "unprognostic (6.56e-3)" "unprognostic (2.21e-1)" "unprognostic (1.77e-2)" "unprognostic (1.03e-1)" CDKN1A "CAP20, CDKN1, CIP1, P21, p21CIP1, p21Cip1/Waf1, SDI1, WAF1" ENSG00000124762 "Cyclin dependent kinase inhibitor 1A" P38936 6 36676460-36687337 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle" "Protein kinase inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal basal cells: 860.9;Esophageal apical cells: 585.4;Esophageal suprabasal cells: 571.5;Ocular epithelial cells: 838.6;Platelets: 535.9;Smooth muscle cells: 568.5;Suprabasal keratinocytes: 559.3;Thymic myoid cells: 533.0;Urothelial cells: 765.4;Vascular smooth muscle cells: 707.4" "Group enriched" "Detected in many" 4 "central nervous system macrophage: 45.6;choroid plexus epithelial cell: 57.6;endothelial cell: 56.7;ependymal cell: 24.7;vascular associated smooth muscle cell: 46.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 74.9" "Group enriched" "Detected in many" 9 "B-cells: 20.8;dendritic cells: 21.5;monocytes: 74.9" "Low cancer specificity" "Detected in all" "Adipose visceral - Neutrophils, Colon - Neutrophils" "Region enhanced" "Detected in all" "olfactory bulb: 76.0" "Low region specificity" "Detected in all" "CAB000064, HPA005946, CAB069401" Supported Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 8: Immune cells - Immune response" "Cluster 40: Non-specific - Unknown function" "Cluster 103: Non-specific - Basic cellular processes" 191 "Nucleoplasm, Nuclear bodies" "CAB000064: , CAB069401: , HPA005946: " "unprognostic (6.40e-2)" "unprognostic (1.16e-2)" "unprognostic (7.94e-3)" "unprognostic (4.53e-2)" "unprognostic (7.99e-3)" "unprognostic (1.48e-1)" "unprognostic (1.03e-2)" "unprognostic (1.85e-3)" "unprognostic (4.01e-2)" "unprognostic (4.78e-2)" "potential prognostic favorable (1.39e-5)" "unprognostic (1.57e-3)" "potential prognostic favorable (8.47e-5)" "unprognostic (3.20e-2)" "potential prognostic favorable (2.11e-6)" "unprognostic (2.70e-2)" "unprognostic (2.15e-1)" "unprognostic (1.22e-2)" "unprognostic (2.07e-3)" "unprognostic (4.48e-2)" "unprognostic (1.94e-1)" "unprognostic (5.62e-3)" "unprognostic (2.81e-2)" "unprognostic (2.98e-2)" "unprognostic (2.66e-1)" "unprognostic (2.01e-1)" "unprognostic (2.93e-2)" "unprognostic (4.43e-2)" "unprognostic (4.34e-2)" "unprognostic (1.34e-1)" "unprognostic (6.25e-2)" CDKN1B "KIP1, P27KIP1" ENSG00000111276 "Cyclin dependent kinase inhibitor 1B" P46527 12 12685498-12722369 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle" "Protein kinase inhibitor" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Müller glia: 187.9;Neutrophils: 254.4;T-cells: 184.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003691, CAB021888, HPA064413" Approved Supported "Nucleoplasm,Primary cilium,Primary cilium transition zone,Centrosome,Basal body,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 65: Brain - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 9: T-cells - Adaptive immunity: Regulation" 134 "Nucleoplasm, Centrosome" "Primary cilium, Primary cilium transition zone, Basal body, Cytosol" "CAB003691: , CAB021888: , HPA064413: " "potential prognostic favorable (6.08e-4)" "unprognostic (3.16e-2)" "unprognostic (1.42e-1)" "unprognostic (2.69e-1)" "unprognostic (1.42e-2)" "unprognostic (2.32e-1)" "unprognostic (1.47e-1)" "unprognostic (2.26e-2)" "unprognostic (2.92e-2)" "unprognostic (4.69e-3)" "potential prognostic favorable (1.19e-5)" "unprognostic (3.15e-3)" "unprognostic (9.23e-2)" "unprognostic (1.52e-2)" "unprognostic (4.28e-3)" "unprognostic (7.66e-2)" "unprognostic (1.15e-1)" "unprognostic (8.87e-3)" "unprognostic (5.64e-2)" "unprognostic (1.11e-2)" "unprognostic (8.48e-2)" "unprognostic (5.31e-2)" "unprognostic (1.50e-2)" "unprognostic (4.41e-1)" "unprognostic (3.37e-2)" "unprognostic (1.71e-2)" "unprognostic (3.84e-2)" "unprognostic (2.43e-1)" "unprognostic (1.51e-1)" "unprognostic (2.39e-2)" "unprognostic (4.25e-1)" CDKN1C "BWCR, BWS, KIP2, P57" ENSG00000129757 "Cyclin dependent kinase inhibitor 1C" P49918 11 2883213-2885775 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle" "Protein kinase inhibitor" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 191.6;ovary: 188.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 146.7;Early spermatids: 147.6;Extravillous trophoblasts: 505.8;Late spermatids: 233.8;Migrating cytotrophoblasts: 133.7;Podocytes: 512.8;Syncytiotrophoblasts: 618.2" "Cell type enhanced" "Detected in many" "oligodendrocyte: 154.7;pericyte: 77.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "intermediate monocyte: 118.2;non-classical monocyte: 288.3" "Lineage enriched" "Detected in many" 13 "monocytes: 288.3" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Kidney - Podocytes, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002924 Enhanced Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 74: Non-specific - Signal transduction" "Cluster 30: White matter - Myelination" "Cluster 70: DU4475 - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 19 "Nucleoplasm, Nuclear bodies" Cytosol "HPA002924: " "unprognostic (1.66e-2)" "unprognostic (2.14e-2)" "unprognostic (7.45e-2)" "unprognostic (1.86e-2)" "unprognostic (3.19e-1)" "unprognostic (3.27e-1)" "unprognostic (2.50e-1)" "unprognostic (3.17e-2)" "unprognostic (1.39e-1)" "unprognostic (3.12e-1)" "unprognostic (4.71e-2)" "potential prognostic favorable (7.92e-5)" "unprognostic (3.95e-2)" "unprognostic (4.72e-2)" "unprognostic (6.36e-2)" "unprognostic (1.90e-1)" "unprognostic (4.64e-2)" "unprognostic (2.69e-1)" "unprognostic (9.56e-2)" "unprognostic (3.60e-1)" "unprognostic (9.78e-2)" "unprognostic (1.09e-1)" "unprognostic (2.86e-1)" "unprognostic (5.66e-2)" "unprognostic (3.52e-1)" "unprognostic (1.27e-1)" "unprognostic (1.65e-1)" "unprognostic (2.27e-2)" "unprognostic (1.47e-1)" CDKN2A "ARF, CDK4I, CDKN2, CMM2, INK4, INK4a, MLM, MTS1, p14, p14ARF, p16, P16-INK4A, p16INK4a, p19, p19Arf" ENSG00000147889 "Cyclin dependent kinase inhibitor 2A" "P42771, Q8N726" 9 21967752-21995301 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, rRNA processing, Transcription, Transcription regulation, Ubl conjugation pathway" DNA-binding "Cancer-related genes, Disease variant, Li-Fraumeni syndrome, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 42.5;pituitary gland: 35.7" "Cell type enhanced" "Detected in many" "Early spermatids: 202.4;Endometrial ciliated cells: 94.1;Gastric progenitor cells: 511.4;Late primary spermatocytes: 158.1;Late spermatids: 681.3;Somatotrophs: 86.7" "Group enriched" "Detected in many" 5 "central nervous system macrophage: 28.1;choroid plexus epithelial cell: 63.1;leukocyte: 20.2" "Cancer enhanced" "Detected in all" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 355.6;Ovary Serous Cystadenocarcinoma (TCGA): 419.0" "Region enriched" "Detected in all" 5 "choroid plexus: 57.4" "Immune cell enhanced" "Detected in many" "T-reg: 37.5" "Group enriched" "Detected in many" 6 "B-cells: 15.7;T-cells: 37.5" "Cancer enhanced" "Detected in many" "cervical cancer: 497.2" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "CAB000093, CAB000445, CAB018232, HPA073143" Enhanced Supported "Nucleoplasm,Primary cilium,Primary cilium tip,Primary cilium transition zone,Cytosol" NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 8: Immune cells - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" 125 Nucleoplasm "Primary cilium, Primary cilium tip, Primary cilium transition zone, Cytosol" "CAB000093: , CAB000445: , CAB018232: , HPA073143: " "unprognostic (3.08e-1)" "unprognostic (7.60e-2)" "unprognostic (1.33e-1)" "unprognostic (1.91e-2)" "unprognostic (5.10e-3)" "potential prognostic unfavorable (8.69e-4)" "unprognostic (1.36e-1)" "potential prognostic favorable (7.53e-5)" "potential prognostic favorable (6.09e-5)" "unprognostic (2.67e-3)" "unprognostic (9.17e-3)" "unprognostic (5.78e-2)" "unprognostic (1.35e-1)" "validated prognostic unfavorable (2.16e-5)" "validated prognostic unfavorable (9.98e-6)" "potential prognostic unfavorable (2.97e-4)" "unprognostic (9.24e-3)" "unprognostic (7.82e-2)" "unprognostic (2.93e-1)" "unprognostic (8.81e-2)" "unprognostic (5.88e-3)" "unprognostic (9.23e-2)" "unprognostic (1.42e-1)" "unprognostic (8.61e-3)" "unprognostic (2.17e-1)" "unprognostic (2.30e-2)" "unprognostic (2.84e-2)" "unprognostic (1.43e-1)" "unprognostic (3.26e-2)" "unprognostic (3.09e-2)" "unprognostic (4.05e-3)" CDKN2AIP "CARF, FLJ20036" ENSG00000168564 "CDKN2A interacting protein" Q9NXV6 4 183444635-183449064 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 185.5;Endometrial ciliated cells: 174.1;Endometrial glandular cells: 301.0;Endometrial luminal cells: 409.9;Esophageal apical cells: 166.8;Ocular epithelial cells: 160.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041397, HPA062142" Approved Enhanced Nucleoplasm NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 23 Nucleoplasm "HPA041397: , HPA062142: " "unprognostic (3.40e-3)" "unprognostic (2.15e-1)" "unprognostic (1.75e-2)" "unprognostic (1.14e-1)" "unprognostic (6.71e-2)" "unprognostic (1.95e-2)" "unprognostic (4.88e-2)" "unprognostic (4.66e-2)" "unprognostic (2.73e-1)" "unprognostic (2.86e-1)" "validated prognostic favorable (3.17e-7)" "validated prognostic favorable (1.58e-4)" "unprognostic (1.59e-2)" "unprognostic (8.23e-2)" "unprognostic (2.12e-1)" "unprognostic (2.38e-1)" "unprognostic (2.61e-1)" "unprognostic (6.09e-3)" "unprognostic (1.54e-2)" "unprognostic (2.00e-1)" "unprognostic (1.20e-1)" "unprognostic (1.28e-1)" "unprognostic (2.63e-2)" "unprognostic (7.96e-2)" "unprognostic (2.59e-1)" "unprognostic (7.63e-3)" "unprognostic (3.38e-2)" "unprognostic (1.30e-1)" "unprognostic (2.91e-1)" "unprognostic (2.12e-3)" "unprognostic (4.36e-1)" CDKN2AIPNL "C2AIL, MGC13017" ENSG00000237190 "CDKN2A interacting protein N-terminal like" Q96HQ2 5 134402065-134411881 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 76.3" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043966 Approved NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 1: Neurons - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 97: Non-specific - Cellular respiration" 9 "HPA043966: " "unprognostic (1.36e-2)" "unprognostic (2.09e-2)" "unprognostic (1.20e-3)" "unprognostic (9.65e-2)" "unprognostic (7.91e-2)" "unprognostic (1.77e-2)" "unprognostic (3.90e-1)" "unprognostic (2.01e-1)" "unprognostic (3.60e-3)" "unprognostic (8.64e-3)" "unprognostic (1.63e-2)" "unprognostic (1.97e-2)" "unprognostic (4.56e-2)" "validated prognostic unfavorable (3.11e-4)" "validated prognostic unfavorable (2.82e-5)" "unprognostic (2.97e-3)" "unprognostic (2.58e-1)" "unprognostic (4.63e-2)" "unprognostic (2.54e-1)" "unprognostic (8.84e-2)" "unprognostic (2.26e-2)" "unprognostic (1.14e-3)" "unprognostic (2.86e-1)" "unprognostic (7.61e-2)" "unprognostic (4.96e-2)" "unprognostic (1.67e-1)" "unprognostic (3.43e-2)" "unprognostic (7.88e-2)" "unprognostic (2.36e-1)" "unprognostic (4.92e-2)" "unprognostic (4.33e-3)" CDKN2B "CDK4I, INK4B, MTS2, P15, p15INK4b, TP15" ENSG00000147883 "Cyclin dependent kinase inhibitor 2B" P42772 9 22002903-22009305 "Human disease related genes, Predicted intracellular proteins" "Cell cycle" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 37.2;intestine: 29.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 107.3;Colonocytes: 232.6;Enterocytes: 201.6;Esophageal apical cells: 558.1;Esophageal suprabasal cells: 283.8;Ocular epithelial cells: 270.2;Suprabasal keratinocytes: 125.7;Urothelial cells: 185.0" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 11.5;endothelial cell: 5.4" "Cancer enhanced" "Detected in all" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 46.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "classical monocyte: 3.3;intermediate monocyte: 3.3;non-classical monocyte: 9.0" "Lineage enriched" "Detected in single" 17 "monocytes: 9.0" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Skin - Outer root sheath cells, Testis - Early spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB000349, HPA052838, HPA063327, HPA073143" Uncertain Approved "Nucleoplasm,Primary cilium,Primary cilium tip,Primary cilium transition zone,Cytosol" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 8: Immune cells - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 26 "Nucleoplasm, Primary cilium transition zone" "Primary cilium, Primary cilium tip, Cytosol" "CAB000349: , HPA052838: , HPA063327: , HPA073143: " "unprognostic (2.07e-2)" "unprognostic (1.11e-1)" "unprognostic (6.57e-2)" "unprognostic (7.39e-2)" "unprognostic (6.69e-2)" "unprognostic (1.52e-2)" "unprognostic (3.55e-1)" "potential prognostic favorable (1.61e-6)" "unprognostic (1.22e-1)" "unprognostic (5.47e-2)" "validated prognostic favorable (9.92e-7)" "validated prognostic favorable (2.84e-4)" "unprognostic (2.53e-3)" "potential prognostic unfavorable (1.57e-4)" "unprognostic (8.70e-2)" "unprognostic (1.36e-1)" "unprognostic (9.08e-3)" "unprognostic (1.58e-1)" "unprognostic (2.14e-1)" "unprognostic (2.63e-1)" "unprognostic (4.20e-2)" "unprognostic (1.44e-1)" "unprognostic (1.33e-3)" "unprognostic (4.35e-2)" "unprognostic (4.54e-2)" "unprognostic (2.00e-2)" "unprognostic (5.65e-2)" "unprognostic (1.75e-2)" "unprognostic (9.07e-2)" "unprognostic (2.35e-1)" "unprognostic (3.02e-3)" CDKN2C "INK4C, p18" ENSG00000123080 "Cyclin dependent kinase inhibitor 2C" P42773 1 50960745-50974634 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 92.4;lymphoid tissue: 89.5" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 72.3;Decidual stromal cells: 52.1;Epididymal efferent duct absorptive cells: 138.0;Hofbauer cells: 55.5;Megakaryocytes: 49.5;Monocyte progenitors: 57.6" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 9.7;oligodendrocyte precursor cell: 7.7" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 129.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005303, CAB018398, HPA019057, HPA019764" Approved Approved Nucleoplasm,Cytosol NA Yes "Cluster 3: Non-specific - Nuclear processes" "Cluster 61: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 27: Non-specific - Cell proliferation" 34 "Nucleoplasm, Cytosol" "CAB005303: , CAB018398: , HPA019057: , HPA019764: " "unprognostic (4.60e-2)" "unprognostic (1.77e-2)" "unprognostic (2.20e-1)" "unprognostic (3.74e-3)" "unprognostic (6.02e-2)" "unprognostic (8.36e-3)" "unprognostic (3.99e-2)" "unprognostic (2.36e-2)" "unprognostic (1.06e-2)" "potential prognostic unfavorable (8.30e-10)" "unprognostic (1.26e-2)" "unprognostic (4.39e-2)" "unprognostic (2.20e-3)" "potential prognostic unfavorable (3.70e-5)" "unprognostic (5.78e-3)" "unprognostic (9.04e-2)" "unprognostic (1.91e-1)" "unprognostic (4.31e-3)" "unprognostic (1.62e-1)" "unprognostic (1.86e-1)" "unprognostic (9.79e-3)" "unprognostic (5.37e-2)" "unprognostic (4.74e-2)" "unprognostic (2.50e-1)" "unprognostic (2.33e-2)" "unprognostic (3.10e-2)" "unprognostic (2.91e-2)" "unprognostic (1.60e-1)" "unprognostic (1.14e-1)" "unprognostic (5.01e-2)" "unprognostic (9.27e-3)" CDKN2D "INK4D, p19" ENSG00000129355 "Cyclin dependent kinase inhibitor 2D" P55273 19 10566460-10569059 "Predicted intracellular proteins" "Cell cycle" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 267.8;brain: 127.7;lymphoid tissue: 72.6" "Cell type enhanced" "Detected in many" "Megakaryocytes: 2262.5;Neutrophil progenitors: 222.0;Neutrophils: 560.8;Platelets: 1542.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Neutrophils, Heart muscle - Macrophages, Liver - Neutrophils, Spleen - Neutrophils_2, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011201, HPA043546" Enhanced Supported Nucleoplasm,Cytosol NA Yes "Cluster 22: Eosinophils - Transcription" "Cluster 78: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 47: Platelets - Hemostasis" 49 Nucleoplasm Cytosol "CAB011201: , HPA043546: " "unprognostic (4.49e-2)" "unprognostic (1.47e-1)" "unprognostic (1.05e-1)" "unprognostic (2.90e-3)" "unprognostic (1.45e-1)" "unprognostic (3.81e-2)" "unprognostic (1.95e-2)" "unprognostic (1.89e-2)" "unprognostic (2.88e-2)" "potential prognostic unfavorable (9.04e-4)" "unprognostic (1.82e-1)" "unprognostic (5.58e-2)" "unprognostic (1.00e-1)" "potential prognostic unfavorable (5.48e-4)" "unprognostic (4.58e-3)" "unprognostic (8.12e-2)" "unprognostic (4.63e-2)" "unprognostic (3.01e-2)" "unprognostic (2.40e-2)" "unprognostic (4.22e-1)" "unprognostic (8.44e-2)" "unprognostic (4.53e-2)" "unprognostic (5.14e-2)" "unprognostic (2.53e-1)" "unprognostic (1.84e-2)" "unprognostic (3.70e-3)" "unprognostic (9.83e-2)" "unprognostic (6.11e-2)" "unprognostic (2.85e-1)" "unprognostic (1.98e-2)" "unprognostic (2.38e-2)" CDKN3 "CDI1, KAP" ENSG00000100526 "Cyclin dependent kinase inhibitor 3" Q16667 14 54396849-54420218 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Hydrolase, Protein phosphatase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 192.4" "Group enriched" "Detected in many" 16 "Early spermatids: 2828.2;Late primary spermatocytes: 2256.0;Late spermatids: 791.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 19.3" "Group enriched" "Detected in all" 6 "NK-cells: 6.2;T-cells: 19.3" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB005285, HPA039311, HPA058874" Enhanced Cytosol NA Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 39: Testis - Nuclear processes" "Cluster 2: Neurons - Nucleosome" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 12 Cytosol "CAB005285: , HPA039311: , HPA058874: " "unprognostic (1.96e-2)" "unprognostic (5.61e-2)" "unprognostic (1.05e-1)" "unprognostic (4.79e-2)" "unprognostic (5.70e-2)" "unprognostic (4.22e-2)" "unprognostic (1.34e-2)" "unprognostic (4.34e-2)" "unprognostic (5.14e-2)" "potential prognostic unfavorable (6.33e-7)" "validated prognostic unfavorable (8.95e-7)" "validated prognostic unfavorable (1.62e-6)" "potential prognostic unfavorable (3.07e-9)" "validated prognostic unfavorable (7.73e-4)" "validated prognostic unfavorable (2.42e-9)" "potential prognostic unfavorable (8.01e-6)" "unprognostic (6.84e-3)" "potential prognostic favorable (8.62e-4)" "unprognostic (2.87e-1)" "unprognostic (3.06e-2)" "unprognostic (8.42e-3)" "potential prognostic unfavorable (4.65e-4)" "unprognostic (5.51e-3)" "unprognostic (2.16e-2)" "unprognostic (2.78e-1)" "unprognostic (2.18e-1)" "unprognostic (2.87e-2)" "unprognostic (4.12e-1)" "unprognostic (3.03e-1)" "unprognostic (8.87e-2)" "unprognostic (9.78e-2)" CDNF ARMETL1 ENSG00000185267 "Cerebral dopamine neurotrophic factor" Q49AH0 10 14819245-14838575 "Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 24.2;tongue: 19.0" "Cell type enriched" "Detected in many" 4 "Late spermatids: 476.1" "Cell type enhanced" "Detected in all" "ependymal cell: 17.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA044587 Uncertain "Secreted in other tissues" "Growth factor" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 46: Brainstem - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 1 "HPA044587: " "unprognostic (6.24e-3)" "unprognostic (3.00e-1)" "unprognostic (6.59e-2)" "unprognostic (4.43e-3)" "potential prognostic favorable (5.32e-4)" "unprognostic (4.89e-3)" "unprognostic (8.34e-2)" "unprognostic (1.47e-2)" "unprognostic (4.76e-3)" "unprognostic (1.61e-1)" "unprognostic (4.56e-2)" "unprognostic (3.94e-1)" "unprognostic (1.98e-1)" "unprognostic (6.62e-2)" "unprognostic (3.89e-1)" "unprognostic (5.06e-2)" "unprognostic (2.10e-2)" "unprognostic (1.09e-1)" "unprognostic (1.33e-2)" CDO1 ENSG00000129596 "Cysteine dioxygenase type 1" Q16878 5 115804733-115816659 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 318.9;liver: 473.7" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 439.1;Epididymal principal cells: 228.0;Hepatocytes: 226.3;Migrating cytotrophoblasts: 262.5;Retinal pigment epithelial cells: 200.4;Syncytiotrophoblasts: 715.7" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Glioblastoma Multiforme (TCGA): 77.7;Liver Hepatocellular Carcinoma (TCGA): 132.9" "Region enriched" "Detected in all" 6 "choroid plexus: 200.4" "Immune cell enhanced" "Detected in single" "memory CD4 T-cell: 1.5" "Lineage enriched" "Detected in single" 15 "T-cells: 1.5" "Cancer enhanced" "Detected in many" "Neuroblastoma: 6.9" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Fibroblasts, Liver - Hepatocytes, Liver - Hepatocytes, Lung - Fibroblasts_1, Prostate - Fibroblasts, Skeletal muscle - Macrophages, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036573, HPA057503" Enhanced Uncertain Nucleoplasm,Cytosol NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 23: Choroid plexus - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 63: Cytotrophoblasts - Basic cellular functions" Nucleoplasm Cytosol "HPA036573: , HPA057503: " "unprognostic (2.97e-1)" "unprognostic (3.21e-2)" "unprognostic (6.82e-3)" "unprognostic (1.38e-1)" "unprognostic (4.40e-1)" "unprognostic (1.91e-1)" "unprognostic (3.67e-2)" "unprognostic (3.72e-2)" "validated prognostic favorable (6.21e-5)" "validated prognostic favorable (2.81e-5)" "unprognostic (3.89e-3)" "unprognostic (1.18e-2)" "unprognostic (2.36e-2)" "unprognostic (9.93e-2)" "unprognostic (1.62e-1)" "unprognostic (2.64e-2)" "unprognostic (7.76e-3)" "unprognostic (1.54e-1)" "unprognostic (1.13e-1)" "potential prognostic unfavorable (2.56e-4)" "unprognostic (3.73e-2)" "unprognostic (4.36e-1)" "unprognostic (3.96e-2)" CDON "CDO, CDON1, Ihog, ORCAM" ENSG00000064309 "Cell adhesion associated, oncogene regulated" Q4KMG0 11 125955796-126063335 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Holoprosencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 13.5" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 125.4;Epicardial cells: 129.6;Fibro-adipogenic progenitors: 258.9;Lactotrophs: 137.8;Mesothelial cells: 536.9;Müller glia: 191.7;Retinal amacrine cells: 114.8;Thyrotrophs: 145.0" "Cell type enhanced" "Detected in all" "upper rhombic lip: 266.1" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 6 "cerebellum: 23.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 14.9" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Mesothelial cells, Adrenal gland - Fibroblasts, Minor Salivary Gland - Fibroblasts, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012422, HPA017377" Uncertain NA NA 3200000 "Cluster 75: Ovary - Mixed function" "Cluster 35: Non-specific - DNA binding" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 108: Fibroblasts - ECM organization" 2 "CAB012422: , HPA017377: " "unprognostic (1.36e-2)" "unprognostic (2.33e-1)" "unprognostic (5.07e-2)" "unprognostic (8.16e-2)" "unprognostic (1.59e-1)" "unprognostic (1.72e-1)" "unprognostic (4.69e-3)" "unprognostic (1.98e-2)" "unprognostic (3.76e-2)" "unprognostic (6.18e-2)" "unprognostic (7.22e-3)" "unprognostic (2.38e-2)" "unprognostic (4.84e-1)" "unprognostic (4.11e-3)" "unprognostic (5.07e-2)" "unprognostic (9.10e-2)" "unprognostic (2.47e-1)" "unprognostic (3.08e-3)" "unprognostic (3.42e-1)" "unprognostic (1.52e-2)" "unprognostic (1.04e-1)" "unprognostic (6.41e-2)" "unprognostic (2.07e-1)" "unprognostic (1.17e-2)" "unprognostic (4.28e-2)" CDPF1 "C22orf40, LOC150383" ENSG00000205643 "Cysteine rich DPF motif domain containing 1" Q6NVV7 22 46244011-46250311 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 15.3;Cytotrophoblasts: 14.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018823 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 66: Non-specific - Mitochondria" "Cluster 94: Gonadal somatic cells - Mixed function" 13 Cytosol Nucleoplasm "HPA018823: " "unprognostic (1.88e-2)" "unprognostic (2.76e-1)" "unprognostic (5.57e-3)" "unprognostic (4.05e-2)" "unprognostic (2.34e-1)" "unprognostic (2.28e-1)" "unprognostic (1.74e-1)" "unprognostic (6.61e-2)" "unprognostic (6.85e-2)" "unprognostic (1.01e-2)" "unprognostic (1.03e-1)" "unprognostic (1.39e-2)" "unprognostic (1.35e-3)" "unprognostic (1.13e-1)" "unprognostic (6.39e-2)" "unprognostic (1.11e-2)" "unprognostic (8.10e-2)" "unprognostic (1.60e-2)" "unprognostic (1.25e-1)" "unprognostic (7.42e-3)" "unprognostic (8.50e-2)" "unprognostic (3.72e-3)" "unprognostic (3.32e-1)" "unprognostic (6.53e-2)" "unprognostic (7.52e-2)" "unprognostic (4.40e-2)" "unprognostic (8.00e-3)" "unprognostic (2.34e-1)" "unprognostic (9.59e-3)" CDR2 "CDR62, Yo" ENSG00000140743 "Cerebellar degeneration related protein 2" Q01850 16 22345936-22437165 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 88.3;Brain inhibitory neurons: 153.6;Choroid plexus epithelial cells: 281.1;Distal convoluted tubule cells: 153.9;Loop of henle epithelial cells: 296.1;Papillary tip epithelial cells: 190.2;Podocytes: 124.4;Proximal tubule cells: 279.7;Renal collecting duct intercalated cells: 161.4;Renal collecting duct principal cells: 217.3;Renal connecting tubule cells: 177.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 6 "granulocytes: 9.4;NK-cells: 4.3;T-cells: 6.7" "Low cancer specificity" "Detected in all" "Heart muscle - Fibroblasts, Minor Salivary Gland - Smooth muscle cells, Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018151, HPA023870" Uncertain Approved Nucleoplasm NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 95 Nucleoplasm "HPA018151: , HPA023870: " "unprognostic (5.22e-2)" "unprognostic (1.69e-2)" "unprognostic (2.86e-1)" "unprognostic (6.67e-3)" "unprognostic (7.42e-2)" "unprognostic (3.70e-1)" "unprognostic (3.32e-2)" "unprognostic (2.42e-2)" "unprognostic (1.66e-1)" "unprognostic (4.46e-2)" "unprognostic (1.40e-1)" "unprognostic (1.22e-2)" "unprognostic (1.12e-1)" "unprognostic (3.61e-2)" "unprognostic (4.15e-1)" "unprognostic (1.08e-1)" "unprognostic (1.98e-2)" "unprognostic (2.85e-1)" "unprognostic (9.69e-2)" "unprognostic (1.52e-1)" "unprognostic (3.56e-2)" "unprognostic (4.98e-2)" "unprognostic (2.07e-1)" "unprognostic (1.89e-1)" "unprognostic (3.40e-2)" "unprognostic (7.64e-2)" "unprognostic (1.94e-1)" "unprognostic (1.20e-3)" "unprognostic (1.76e-1)" "unprognostic (1.47e-2)" "unprognostic (8.26e-2)" CDR2L HUMPPA ENSG00000109089 "Cerebellar degeneration related protein 2 like" Q86X02 17 74987632-75005800 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 58.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 58.0;Endometrial glandular cells: 30.6;Endometrial luminal cells: 49.6;Endometrial secretory cells: 34.7;Late spermatids: 111.1" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 33.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022015 Enhanced Approved Cytosol NA NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 80 Cytosol "HPA022015: " "unprognostic (1.77e-2)" "unprognostic (3.37e-2)" "unprognostic (2.08e-1)" "unprognostic (2.67e-2)" "unprognostic (3.88e-2)" "unprognostic (2.31e-3)" "unprognostic (1.41e-1)" "unprognostic (1.01e-1)" "unprognostic (1.06e-2)" "unprognostic (2.35e-1)" "unprognostic (1.41e-2)" "unprognostic (1.24e-1)" "unprognostic (2.37e-1)" "unprognostic (6.66e-2)" "unprognostic (2.86e-2)" "unprognostic (1.16e-3)" "unprognostic (3.11e-2)" "unprognostic (4.44e-2)" "unprognostic (7.03e-2)" "unprognostic (5.32e-2)" "unprognostic (1.44e-1)" "unprognostic (2.59e-2)" "unprognostic (1.38e-1)" "unprognostic (1.49e-1)" "unprognostic (1.35e-1)" "unprognostic (4.00e-1)" "unprognostic (4.40e-2)" "unprognostic (1.02e-1)" "unprognostic (4.32e-2)" "unprognostic (1.90e-2)" "unprognostic (1.76e-1)" CDRT15 ENSG00000223510 "CMT1A duplicated region transcript 15" Q96T59 17 14235673-14236862 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 20.0" "Group enriched" "Detected in some" 44 "Early spermatids: 46.7;Late primary spermatocytes: 112.8;Late spermatids: 77.0" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Late spermatids" HPA055952 Uncertain Approved "Plasma membrane" NA NA "Cluster 47: Testis - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" "Plasma membrane" "HPA055952: " "unprognostic (3.05e-1)" "unprognostic (1.41e-2)" "unprognostic (3.80e-2)" "unprognostic (3.07e-1)" "unprognostic (4.48e-2)" "unprognostic (1.62e-1)" "unprognostic (8.72e-2)" CDRT15L2 ENSG00000214819 "CMT1A duplicated region transcript 15 like 2" A8MXV6 17 20579724-20580911 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "testis: 14.9" "Group enriched" "Detected in some" 25 "Early spermatids: 35.2;Late primary spermatocytes: 85.9" "Cell type enhanced" "Detected in single" "hippocampal CA4: 1.2" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "cerebral cortex: 1.4;hippocampal formation: 3.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 29: Forebrain - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" CDRT4 FLJ36674 ENSG00000239704 "CMT1A duplicated region transcript 4" Q8N9R6 17 15436015-15475728 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 30.8" "Cell type enhanced" "Detected in some" "Astrocytes: 55.1;Bergmann glia: 44.2;Brain excitatory neurons: 54.2;Brain inhibitory neurons: 61.0;Choroid plexus epithelial cells: 133.2;Early spermatids: 57.0;Ependymal cells: 110.7;Late spermatids: 197.4;Microglia: 50.3;Oligodendrocyte progenitor cells: 74.8;Oligodendrocytes: 60.9;Other brain neurons: 62.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA021590 Uncertain Approved Mitochondria NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 20: Pituitary gland - Hormone signaling" "Cluster 1: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 22: Non-specific - Basic cellular functions" 3 Mitochondria "HPA021590: " "unprognostic (1.20e-1)" "potential prognostic favorable (4.96e-4)" "unprognostic (1.28e-2)" "unprognostic (1.33e-1)" "unprognostic (1.31e-1)" "unprognostic (1.75e-2)" "unprognostic (5.51e-2)" "unprognostic (1.99e-2)" "unprognostic (7.43e-3)" "unprognostic (5.59e-2)" "potential prognostic unfavorable (2.44e-7)" "unprognostic (2.30e-1)" "unprognostic (1.33e-1)" "unprognostic (6.06e-2)" "unprognostic (2.07e-1)" "unprognostic (4.40e-2)" "unprognostic (5.79e-2)" "unprognostic (1.65e-1)" "unprognostic (4.06e-1)" "unprognostic (9.07e-2)" "unprognostic (8.04e-2)" "potential prognostic favorable (1.63e-4)" "unprognostic (5.49e-3)" "unprognostic (1.07e-1)" "unprognostic (2.97e-1)" "unprognostic (1.41e-2)" "unprognostic (3.94e-2)" "unprognostic (5.64e-2)" "unprognostic (2.66e-1)" "unprognostic (2.74e-1)" "unprognostic (2.17e-2)" CDS1 ENSG00000163624 "CDP-diacylglycerol synthase 1" Q92903 4 84583127-84651334 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 401.8;Epididymal efferent duct ciliated cells: 287.5;Esophageal apical cells: 372.4;Fallopian tube ciliated cells: 292.6;Podocytes: 226.4;Respiratory ciliated cells: 428.1" "Cell type enhanced" "Detected in all" "ependymal cell: 204.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal cortex cells, Lung - Alveolar cells type 2, Spleen - Macrophages, Stomach - Gastric mucous cells, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036187, HPA064546" Enhanced NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 107: Ciliated cells - Cilia assembly & function" 21 "HPA036187: , HPA064546: " "unprognostic (4.48e-1)" "unprognostic (3.78e-2)" "unprognostic (2.15e-1)" "unprognostic (3.60e-2)" "potential prognostic favorable (5.11e-4)" "unprognostic (6.63e-2)" "unprognostic (2.68e-2)" "unprognostic (4.13e-2)" "unprognostic (3.09e-1)" "unprognostic (7.12e-2)" "validated prognostic favorable (2.39e-12)" "validated prognostic favorable (9.62e-4)" "unprognostic (4.10e-3)" "unprognostic (4.06e-3)" "unprognostic (5.09e-2)" "unprognostic (3.55e-2)" "unprognostic (1.91e-1)" "unprognostic (4.29e-2)" "unprognostic (3.28e-1)" "unprognostic (4.12e-1)" "unprognostic (2.17e-1)" "unprognostic (3.06e-2)" "unprognostic (1.50e-1)" "unprognostic (9.18e-2)" "unprognostic (2.58e-2)" "unprognostic (9.66e-3)" "unprognostic (7.94e-2)" "unprognostic (1.35e-1)" "unprognostic (1.56e-1)" "unprognostic (3.02e-1)" "unprognostic (1.11e-1)" CDS2 ENSG00000101290 "CDP-diacylglycerol synthase 2" O95674 20 5126879-5197887 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 209.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Smooth muscle cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019698 Approved Approved "Endoplasmic reticulum" No No "Cluster 35: Neutrophils - Protein binding" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 24: Neutrophils - Innate immunity signal integration" 68 "Endoplasmic reticulum" "HPA019698: " "unprognostic (1.36e-2)" "unprognostic (8.54e-2)" "unprognostic (4.03e-2)" "unprognostic (3.37e-2)" "unprognostic (1.57e-1)" "unprognostic (4.20e-2)" "unprognostic (9.96e-2)" "unprognostic (1.74e-2)" "unprognostic (2.00e-1)" "unprognostic (2.23e-2)" "validated prognostic favorable (1.47e-7)" "validated prognostic favorable (3.17e-4)" "unprognostic (6.38e-3)" "unprognostic (4.43e-2)" "unprognostic (9.08e-2)" "unprognostic (1.55e-1)" "unprognostic (1.65e-1)" "potential prognostic unfavorable (2.80e-4)" "unprognostic (4.46e-1)" "unprognostic (2.47e-2)" "unprognostic (8.10e-2)" "unprognostic (2.18e-3)" "unprognostic (2.33e-1)" "unprognostic (1.73e-1)" "unprognostic (1.42e-1)" "unprognostic (5.32e-2)" "unprognostic (2.53e-1)" "unprognostic (3.59e-2)" "unprognostic (2.76e-1)" "unprognostic (1.79e-1)" "unprognostic (7.63e-2)" CDSN D6S586E ENSG00000204539 Corneodesmosin 6 31115087-31120446 "Human disease related genes, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 88 "skin 1: 663.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 2.9;Endometrial glandular cells: 1.2;Endometrial luminal cells: 2.7;Epicardial cells: 2.3;Renal collecting duct principal cells: 1.3" "Group enriched" "Detected in some" 4 "fibroblast: 4.3;oligodendrocyte: 1.6" "Cancer enriched" "Detected in some" 4 "Skin Cutaneous Melanoma (TCGA): 42.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "breast cancer: 2.0;head and neck cancer: 1.4" "Skin - Keratinocyte (granular)" "Region enhanced" "Detected in some" "cerebral cortex: 1.5" "Not detected" "Not detected" "HPA044730, HPA054184" Enhanced "Secreted in other tissues" NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 27: Breast cancer - Unknown function" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" "HPA044730: , HPA054184: " "unprognostic (1.06e-3)" "unprognostic (1.01e-1)" "unprognostic (4.86e-1)" "unprognostic (2.67e-2)" "unprognostic (4.22e-1)" "unprognostic (1.10e-1)" CDT1 "DUP, RIS2" ENSG00000167513 "Chromatin licensing and DNA replication factor 1" Q9H211 16 88803789-88809258 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, DNA replication, Mitosis" "Disease variant, Dwarfism, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "bone marrow: 36.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 57.8;Differentiating spermatogonia: 63.0;Enteric stem cells: 38.1;Enteric transient amplifying cells: 58.5;Erythrocyte progenitors: 84.3;Esophageal basal cells: 53.5;Extravillous trophoblasts: 101.6;Megakaryocyte progenitors: 49.1;Megakaryocytes: 30.9;Migrating cytotrophoblasts: 82.8;Monocyte progenitors: 38.7;Oocytes: 36.8;Paneth cells: 50.3;Respiratory deuterosomal cells: 50.8" "Cell type enhanced" "Detected in some" "lower rhombic lip: 2.1;mammillary body: 2.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Pituitary gland - Gonadotropes, Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA017224 Approved Supported "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 22: Eosinophils - Transcription" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 27: Non-specific - Cell proliferation" 43 Nucleoplasm "Nuclear bodies" "HPA017224: " "unprognostic (2.31e-1)" "unprognostic (2.11e-1)" "unprognostic (4.89e-1)" "unprognostic (5.33e-2)" "unprognostic (1.52e-1)" "unprognostic (1.79e-1)" "unprognostic (2.69e-1)" "unprognostic (6.85e-2)" "unprognostic (3.18e-1)" "unprognostic (1.12e-3)" "unprognostic (3.14e-3)" "unprognostic (1.20e-3)" "unprognostic (1.26e-3)" "validated prognostic unfavorable (7.13e-7)" "validated prognostic unfavorable (2.15e-10)" "potential prognostic unfavorable (1.97e-5)" "unprognostic (2.09e-3)" "unprognostic (2.28e-2)" "unprognostic (1.58e-1)" "unprognostic (7.91e-2)" "unprognostic (9.35e-3)" "unprognostic (4.34e-2)" "potential prognostic unfavorable (3.66e-4)" "unprognostic (1.01e-1)" "unprognostic (3.79e-2)" "unprognostic (1.07e-1)" "potential prognostic unfavorable (1.72e-4)" "unprognostic (5.78e-2)" "unprognostic (1.49e-1)" "unprognostic (7.14e-2)" "unprognostic (9.05e-2)" CDV3 H41 ENSG00000091527 "CDV3 homolog" Q9UKY7 3 133573686-133590261 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 394.3;Late spermatids: 959.4;Plasma cells: 377.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029761, HPA029762, HPA029763" Enhanced Approved "Nucleoli,Plasma membrane,Cytosol" NA NA 870000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 78: Plasma cells - Antibody production & ER-stress response" 2 Cytosol "Nucleoli, Plasma membrane" "HPA029761: , HPA029762: , HPA029763: " "unprognostic (5.87e-3)" "unprognostic (1.66e-1)" "unprognostic (1.04e-1)" "unprognostic (1.33e-3)" "unprognostic (5.97e-2)" "unprognostic (1.12e-1)" "unprognostic (5.42e-2)" "unprognostic (5.33e-2)" "unprognostic (1.86e-1)" "unprognostic (3.20e-2)" "potential prognostic favorable (5.56e-4)" "unprognostic (2.28e-1)" "unprognostic (1.07e-1)" "potential prognostic unfavorable (2.08e-4)" "unprognostic (1.39e-3)" "unprognostic (3.04e-2)" "unprognostic (5.13e-2)" "unprognostic (4.52e-1)" "unprognostic (2.79e-1)" "unprognostic (1.64e-1)" "potential prognostic unfavorable (7.12e-5)" "unprognostic (3.86e-3)" "unprognostic (1.00e-2)" "unprognostic (2.48e-2)" "unprognostic (7.72e-2)" "unprognostic (2.06e-1)" "unprognostic (3.79e-2)" "unprognostic (6.09e-2)" "unprognostic (2.27e-1)" "unprognostic (1.01e-2)" "unprognostic (1.40e-1)" CDX1 ENSG00000113722 "Caudal type homeobox 1" P47902 5 150166778-150184558 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "intestine: 93.3" "Cell type enhanced" "Detected in some" "Colonocytes: 351.9;Enteric stem cells: 263.6;Enteric transient amplifying cells: 284.3;Enterocytes: 175.8;Goblet cells: 156.1;Neuroendocrine cells: 64.5;Paneth cells: 166.3;Tuft cells: 138.3" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Colon Adenocarcinoma (TCGA): 205.1;Rectum Adenocarcinoma (TCGA): 203.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Bile duct cancer: 25.3;colorectal cancer: 80.2" "Adipose subcutaneous - Adipose progenitor cells, Colon - Colon enterocytes" "Not detected" "Not detected" "Region enhanced" "Detected in some" "thalamus: 2.1" HPA055196 Enhanced NA NA "Cluster 77: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 4 "HPA055196: " "unprognostic (1.23e-1)" "unprognostic (1.27e-3)" "unprognostic (9.01e-2)" "unprognostic (5.94e-2)" "unprognostic (2.94e-3)" "unprognostic (3.74e-1)" "unprognostic (4.64e-2)" "unprognostic (4.65e-2)" "unprognostic (2.15e-2)" "unprognostic (7.86e-3)" "unprognostic (8.39e-3)" "unprognostic (2.16e-1)" "unprognostic (3.86e-1)" CDX2 CDX3 ENSG00000165556 "Caudal type homeobox 2" Q99626 13 27960918-27969315 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "intestine: 45.1" "Cell type enhanced" "Detected in some" "Colonocytes: 284.5;Enteric stem cells: 219.3;Enteric transient amplifying cells: 192.9;Enterocytes: 216.6;Goblet cells: 193.7;Neuroendocrine cells: 52.6;Paneth cells: 150.8;Tuft cells: 46.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Colon Adenocarcinoma (TCGA): 84.0;Rectum Adenocarcinoma (TCGA): 90.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "colorectal cancer: 73.2" "Colon - Colon enterocytes" "Not detected" "Not detected" "Not detected" "Not detected" "CAB002221, HPA045669, HPA072152" Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 77: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 8 Nucleoplasm "Vesicles, Cytosol" "CAB002221: , HPA045669: , HPA072152: " "unprognostic (1.84e-1)" "unprognostic (4.16e-1)" "unprognostic (5.62e-2)" "unprognostic (1.00e-1)" "unprognostic (1.16e-1)" "unprognostic (3.44e-3)" "unprognostic (1.14e-1)" "unprognostic (8.97e-3)" "unprognostic (1.18e-1)" CDX4 ENSG00000131264 "Caudal type homeobox 4" O14627 X 73447053-73455171 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 9 "skin 1: 1.0" "Cell type enhanced" "Detected in single" "Undifferentiated spermatogonia: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Keratinocyte (other)" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA043714, HPA056528" Uncertain Approved "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 37: Skin - Keratinization" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 8 "Nucleoplasm, Nuclear speckles" Cytosol "HPA043714: , HPA056528: " CDY1 CDY1A ENSG00000172288 "Chromodomain Y-linked 1" Q9Y6F8 Y 25622117-25624902 "Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 13 "testis: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA066682 Supported NA NA "Cluster 57: Testis - Spermatogenesis" "HPA066682: " CDY1B ENSG00000172352 "Chromodomain Y-linked 1B" Q9Y6F8 Y 24045229-24048019 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 18 "testis: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA066682 Supported NA NA "Cluster 6: Testis - Spermatogenesis" "HPA066682: " CDY2A CDY2 ENSG00000182415 "Chromodomain Y-linked 2A" Q9Y6F7 Y 18025787-18027746 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "epididymis: 1.0;testis: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA066682 Supported NA NA "Cluster 22: Epididymis - Mixed function" "HPA066682: " CDY2B CDY ENSG00000129873 "Chromodomain Y-linked 2B" Q9Y6F7 Y 17878260-17880220 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA066682 Supported NA NA "HPA066682: " CDYL "CDYL1, DKFZP586C1622" ENSG00000153046 "Chromodomain Y like" Q9Y232 6 4706159-4955551 "Predicted intracellular proteins" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Lyase, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial glandular cells: 489.8;pDCs: 447.1;Syncytiotrophoblasts: 434.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 6.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035578 Enhanced Supported "Nuclear speckles" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 51: Secretory epithelial cells - Mixed function" 25 "Nuclear speckles" "HPA035578: " "unprognostic (2.41e-2)" "unprognostic (1.24e-1)" "unprognostic (5.60e-2)" "unprognostic (3.12e-2)" "unprognostic (2.05e-1)" "unprognostic (1.02e-1)" "unprognostic (2.86e-2)" "potential prognostic favorable (5.68e-4)" "unprognostic (2.66e-1)" "potential prognostic unfavorable (6.99e-4)" "potential prognostic favorable (2.27e-6)" "unprognostic (5.23e-3)" "unprognostic (2.63e-1)" "potential prognostic unfavorable (9.59e-4)" "unprognostic (4.60e-2)" "unprognostic (9.66e-2)" "unprognostic (3.80e-1)" "unprognostic (4.80e-3)" "unprognostic (2.73e-2)" "unprognostic (2.07e-1)" "unprognostic (1.71e-2)" "unprognostic (2.46e-2)" "unprognostic (1.89e-2)" "unprognostic (1.31e-1)" "unprognostic (9.13e-3)" "unprognostic (3.00e-1)" "potential prognostic unfavorable (7.29e-5)" "unprognostic (1.83e-2)" "unprognostic (5.95e-2)" "unprognostic (1.88e-2)" "unprognostic (5.82e-2)" CDYL2 FLJ38866 ENSG00000166446 "Chromodomain Y like 2" Q8N8U2 16 80597907-80804598 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 13.2" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 409.3;Neutrophil progenitors: 120.6;Prostatic glandular cells: 362.8;Renal collecting duct intercalated cells: 157.0;Sertoli cells: 216.2" "Cell type enhanced" "Detected in all" "endothelial cell: 339.9" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 13.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "intermediate monocyte: 1.0;non-classical monocyte: 4.0" "Lineage enriched" "Detected in single" 8 "monocytes: 4.0" "Cancer enhanced" "Detected in many" "prostate cancer: 16.4" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041016 Approved NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 27: Cerebellum - Synaptic function" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 60: Prostate cancer - Unknown function" "Cluster 51: Secretory epithelial cells - Mixed function" 10 "HPA041016: " "unprognostic (2.93e-3)" "unprognostic (1.13e-1)" "unprognostic (2.02e-1)" "unprognostic (1.23e-1)" "unprognostic (3.26e-1)" "unprognostic (2.21e-1)" "unprognostic (2.91e-1)" "unprognostic (4.18e-2)" "unprognostic (5.47e-2)" "unprognostic (2.60e-3)" "potential prognostic favorable (1.16e-5)" "unprognostic (3.60e-2)" "unprognostic (2.40e-1)" "unprognostic (5.61e-2)" "unprognostic (2.20e-2)" "potential prognostic unfavorable (7.42e-4)" "unprognostic (1.84e-2)" "unprognostic (5.76e-3)" "unprognostic (1.58e-1)" "unprognostic (1.29e-1)" "unprognostic (2.80e-3)" "unprognostic (1.79e-1)" "unprognostic (3.06e-2)" "unprognostic (5.49e-2)" "unprognostic (1.25e-2)" "unprognostic (2.31e-1)" "unprognostic (1.16e-1)" "unprognostic (1.57e-1)" CEACAM1 "BGP, BGP1, CD66a" ENSG00000079385 "CEA cell adhesion molecule 1" P13688 19 42507304-42561234 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 230.9" "Cell type enhanced" "Detected in many" "Adipocytes: 257.2;Colonocytes: 898.9;Esophageal apical cells: 1270.5;Esophageal suprabasal cells: 197.5;Neutrophil progenitors: 472.9;Ocular epithelial cells: 194.0;Tuft cells: 265.1" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Colon Adenocarcinoma (TCGA): 122.5;Rectum Adenocarcinoma (TCGA): 128.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "eosinophil: 44.1;neutrophil: 26.9" "Lineage enriched" "Detected in many" 13 "granulocytes: 44.1" "Low cancer specificity" "Detected in many" "Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Colon - Colon enterocytes, Kidney - Endothelial cells, Skin - Eccrine sweat gland cells" "CAB002146, HPA011041" Enhanced "Intracellular and membrane" "No annotated function" NA NA 7200000 "Cluster 21: Neutrophils - Unknown function" "Cluster 17: Intestine - Digestion" "Cluster 15: Non-specific - Transcription" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 6 "CAB002146: , HPA011041: " "unprognostic (1.35e-1)" "unprognostic (8.56e-3)" "unprognostic (7.91e-3)" "unprognostic (1.27e-1)" "unprognostic (2.38e-1)" "unprognostic (2.37e-2)" "unprognostic (6.50e-2)" "unprognostic (1.47e-2)" "unprognostic (1.06e-1)" "potential prognostic favorable (6.68e-7)" "unprognostic (3.29e-3)" "unprognostic (1.63e-2)" "unprognostic (7.77e-2)" "unprognostic (1.13e-2)" "unprognostic (6.77e-2)" "unprognostic (1.24e-1)" "unprognostic (1.46e-1)" "unprognostic (2.90e-1)" "unprognostic (6.95e-2)" "unprognostic (1.44e-1)" "unprognostic (2.31e-2)" "unprognostic (2.22e-2)" "unprognostic (2.54e-1)" "unprognostic (1.41e-1)" "unprognostic (9.31e-2)" "unprognostic (1.58e-1)" "unprognostic (8.73e-2)" "unprognostic (1.04e-1)" "unprognostic (4.74e-2)" "unprognostic (3.37e-1)" CEACAM16 DFNA4B ENSG00000213892 "CEA cell adhesion molecule 16, tectorial membrane component" Q2WEN9 19 44699151-44710718 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "pancreas: 1.9" "Cell type enhanced" "Detected in some" "Adrenal cortex cells: 2.2;Colonocytes: 3.3;Enteric stem cells: 2.1;Epididymal basal cells: 1.5;Epididymal clear cells: 2.0;Esophageal apical cells: 5.0;Goblet cells: 2.9;Lactotrophs: 1.5;Paneth cells: 3.9;Retinal bipolar cells: 7.7;Thyrotrophs: 3.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA045075 Uncertain "Secreted in other tissues" "No annotated function" NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "HPA045075: " CEACAM18 ENSG00000213822 "CEA cell adhesion molecule 18" A8MTB9 19 51478539-51491301 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 39 "intestine: 21.4" "Cell type enriched" "Detected in some" 6 "Enterocytes: 41.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Pancreatic Adenocarcinoma (TCGA): 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 1.0;Gastric cancer: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA059487 Uncertain Approved Midbody Yes NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 1: Enterocytes - Absorption and Digestion" Midbody "HPA059487: " "unprognostic (5.85e-2)" CEACAM19 CEAL1 ENSG00000186567 "CEA cell adhesion molecule 19" Q7Z692 19 44662278-44684359 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 37.0;Podocytes: 147.9;Tuft cells: 57.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells" "Not detected" "Not detected" "Region enhanced" "Detected in single" "hippocampal formation: 1.5" "HPA014462, HPA052865" Uncertain Approved Nucleoplasm,Nucleoli,Mitochondria NA NA "Cluster 24: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 15: Kidney cancer - Membrane components" "Cluster 57: Podocytes - Glomerular filtration" "Nucleoli, Mitochondria" Nucleoplasm "HPA014462: , HPA052865: " "unprognostic (7.80e-3)" "unprognostic (6.54e-2)" "unprognostic (1.85e-1)" "unprognostic (3.12e-2)" "unprognostic (1.51e-1)" "unprognostic (8.05e-2)" "unprognostic (1.80e-1)" "unprognostic (6.52e-2)" "unprognostic (2.52e-1)" "unprognostic (1.16e-1)" "unprognostic (4.77e-3)" "unprognostic (4.61e-2)" "potential prognostic unfavorable (1.45e-4)" "unprognostic (6.93e-2)" "unprognostic (1.54e-2)" "unprognostic (2.81e-3)" "unprognostic (5.04e-1)" "unprognostic (7.52e-2)" "unprognostic (1.33e-1)" "unprognostic (2.28e-2)" "unprognostic (4.34e-2)" "unprognostic (1.30e-2)" "unprognostic (2.88e-3)" "unprognostic (2.90e-2)" "unprognostic (3.52e-2)" "unprognostic (1.42e-1)" "unprognostic (2.06e-2)" "unprognostic (6.99e-3)" "unprognostic (1.78e-2)" "unprognostic (5.87e-2)" "unprognostic (1.21e-1)" CEACAM20 UNQ9366 ENSG00000273777 "CEA cell adhesion molecule 20" Q6UY09 19 44501677-44529788 "Predicted membrane proteins" Immunity "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "intestine: 35.6" "Group enriched" "Detected in some" 8 "Enterocytes: 110.4;Neuroendocrine cells: 32.1" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Prostate Adenocarcinoma (TCGA): 8.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "prostate cancer: 21.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 60: Prostate cancer - Unknown function" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" "unprognostic (2.39e-2)" "unprognostic (2.06e-1)" "unprognostic (5.89e-2)" CEACAM21 "FLJ13540, R29124_1" ENSG00000007129 "CEA cell adhesion molecule 21" Q3KPI0 19 41549518-41586844 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 16.5;lymphoid tissue: 9.9" "Cell type enhanced" "Detected in some" "B-cells: 2.9;Hepatic stellate cells: 6.5;Macrophages: 3.3;Megakaryocytes: 12.4;Microglia: 35.5;Neutrophil progenitors: 4.1;Neutrophils: 3.8;NK-cells: 6.7;Other brain neurons: 5.3;T-cells: 5.1" "Group enriched" "Detected in some" 8 "central nervous system macrophage: 43.6;leukocyte: 66.0" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 5.2" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 8 "Leukemia: 3.0;lymphoma: 1.5;Myeloma: 5.8" "Prostate - T-cells, Testis - Late spermatids, Thyroid gland - T-cells" HPA043411 Uncertain NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 35: RS4;11 - Unknown function" "Cluster 102: Non-specific - Mixed function" "HPA043411: " "unprognostic (7.73e-3)" "unprognostic (1.49e-1)" "unprognostic (1.52e-2)" "unprognostic (1.20e-1)" "unprognostic (2.84e-1)" "potential prognostic unfavorable (9.85e-4)" "unprognostic (1.66e-1)" "unprognostic (8.39e-3)" "potential prognostic favorable (8.29e-4)" "unprognostic (9.44e-2)" "unprognostic (2.76e-2)" "unprognostic (1.04e-1)" "unprognostic (5.23e-2)" "unprognostic (1.38e-1)" "unprognostic (7.16e-2)" "unprognostic (5.72e-2)" CEACAM3 "CD66d, CGM1" ENSG00000170956 "CEA cell adhesion molecule 3" P40198 19 41796587-41811554 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "bone marrow: 41.8" "Group enriched" "Detected in some" 13 "Neutrophil progenitors: 138.1;Neutrophils: 225.8" "Cell type enriched" "Detected in single" 15 "leukocyte: 1.6" "Cancer enhanced" "Detected in single" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 1.2" "Region enhanced" "Detected in single" "cerebral cortex: 1.9" "Immune cell enriched" "Detected in many" 6 "neutrophil: 290.5" "Lineage enriched" "Detected in many" 6 "granulocytes: 290.5" "Not detected" "Not detected" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Lung - NK-cells (Lung), Pituitary gland - Neutrophils, Stomach - Neutrophils, Thyroid gland - Neutrophils" HPA011041 Approved NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 15: Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 4 "HPA011041: " "potential prognostic favorable (9.44e-4)" "unprognostic (1.35e-1)" CEACAM4 CGM7 ENSG00000105352 "CEA cell adhesion molecule 4" O75871 19 41619015-41627074 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 33.1" "Cell type enhanced" "Detected in some" "cDC: 2.4;Hematopoietic stem cells: 10.7;Kupffer cells: 5.1;Macrophages: 3.1;Microglia: 2.7;Monocyte progenitors: 5.7;monocytes: 5.8;Neutrophil progenitors: 4.5;Neutrophils: 17.7;Platelets: 2.8" "Cell type enhanced" "Detected in single" "central nervous system macrophage: 3.7" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "neutrophil: 241.0" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Adipose visceral - Neutrophils, Kidney - Macrophages, Liver - Neutrophils, Lung - Neutrophils_2, Prostate - Macrophages, Skin - Macrophages, Spleen - Neutrophils_2, Thyroid gland - Macrophages" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" "unprognostic (5.73e-3)" "unprognostic (8.81e-2)" "unprognostic (1.09e-1)" "unprognostic (1.27e-2)" "unprognostic (2.35e-2)" CEACAM5 "CD66e, CEA" ENSG00000105388 "CEA cell adhesion molecule 5" P06731 19 41708585-41730433 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell adhesion" "Cancer-related genes, Oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "intestine: 920.3" "Group enriched" "Detected in some" 4 "Colonocytes: 184.2;Esophageal apical cells: 143.5;Foveolar cells: 51.2;Goblet cells: 86.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 1966.2;Rectum Adenocarcinoma (TCGA): 2245.2" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 196.8;Gallbladder cancer: 484.8" "Colon - Colon enterocytes, Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Urothelial cells, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells, Thyroid gland - Parafollicular cells" "CAB000021, CAB000022, HPA011041, HPA019758" Enhanced Supported "Plasma membrane" NA NA 400000 "Cluster 17: Intestine - Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 1 "Plasma membrane" "CAB000021: , CAB000022: , HPA011041: , HPA019758: " "unprognostic (1.28e-1)" "unprognostic (1.24e-2)" "unprognostic (3.30e-1)" "unprognostic (1.37e-1)" "unprognostic (1.59e-2)" "unprognostic (8.80e-3)" "unprognostic (4.29e-3)" "potential prognostic unfavorable (2.31e-4)" "unprognostic (2.01e-1)" "unprognostic (4.91e-1)" "unprognostic (8.67e-2)" "unprognostic (1.84e-1)" "unprognostic (1.11e-1)" "unprognostic (4.32e-2)" "unprognostic (2.67e-2)" "unprognostic (1.37e-2)" "unprognostic (3.76e-1)" "unprognostic (8.05e-2)" "unprognostic (2.00e-2)" "unprognostic (2.82e-1)" "unprognostic (4.32e-1)" "unprognostic (1.44e-1)" "unprognostic (1.31e-1)" CEACAM6 "CD66c, NCA" ENSG00000086548 "CEA cell adhesion molecule 6" P40199 19 41750977-41772211 "Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell adhesion" "Cancer-related genes, Oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 171.4;esophagus: 194.9;intestine: 206.9;lung: 270.1;salivary gland: 177.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 1945.0;Colonocytes: 473.1;Esophageal apical cells: 2065.5;Gastric progenitor cells: 302.5;Neutrophil progenitors: 244.6;Respiratory deuterosomal cells: 465.4;Respiratory secretory cells: 449.1;Salivary duct cells: 293.3;Transitional alveolar cells: 847.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 1045.8;Rectum Adenocarcinoma (TCGA): 1052.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.1" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "pancreatic cancer: 386.8" "Colon - Colon enterocytes, Lung - Alveolar cells type 1, Prostate - Urothelial cells, Skin - Eccrine sweat gland cells, Spleen - Neutrophils_1" "CAB008370, HPA011041" Enhanced NA NA 1700000 "Cluster 11: Esophagus - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 28 "CAB008370: , HPA011041: " "unprognostic (1.08e-1)" "unprognostic (1.24e-3)" "unprognostic (1.77e-1)" "unprognostic (1.69e-1)" "unprognostic (2.11e-1)" "unprognostic (7.57e-3)" "unprognostic (1.17e-2)" "unprognostic (3.50e-1)" "unprognostic (1.95e-2)" "unprognostic (2.39e-1)" "unprognostic (3.73e-1)" "unprognostic (5.63e-2)" "unprognostic (1.28e-2)" "unprognostic (7.58e-2)" "unprognostic (3.99e-2)" "unprognostic (3.06e-1)" "unprognostic (5.32e-3)" "unprognostic (2.77e-1)" "unprognostic (2.44e-1)" "unprognostic (5.33e-3)" "unprognostic (3.08e-2)" "unprognostic (1.83e-1)" "unprognostic (3.68e-1)" "unprognostic (3.65e-2)" "unprognostic (2.84e-1)" "unprognostic (3.93e-2)" CEACAM7 "CEA, CGM2" ENSG00000007306 "CEA cell adhesion molecule 7" Q14002 19 41673303-41706976 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "intestine: 612.7" "Group enriched" "Detected in some" 10 "Colonocytes: 169.1;Esophageal apical cells: 98.7" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 77.2;Rectum Adenocarcinoma (TCGA): 105.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 2.3;colorectal cancer: 3.4;ovarian cancer: 3.2" "Colon - Colon enterocytes" "HPA069621, HPA073910" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 17: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 1 "Plasma membrane" Cytosol "HPA069621: , HPA073910: " "unprognostic (1.56e-1)" "unprognostic (4.49e-2)" "unprognostic (1.62e-1)" "unprognostic (9.68e-2)" "unprognostic (1.47e-2)" "unprognostic (2.14e-2)" "unprognostic (7.51e-2)" "unprognostic (1.54e-3)" "unprognostic (1.48e-1)" "unprognostic (2.18e-1)" "unprognostic (1.79e-1)" "unprognostic (1.83e-2)" "unprognostic (2.37e-1)" "unprognostic (2.01e-2)" "unprognostic (1.21e-1)" "unprognostic (1.49e-1)" "unprognostic (6.80e-2)" CEACAM8 "CD66b, CGM6" ENSG00000124469 "CEA cell adhesion molecule 8" P31997 19 42580243-42595055 "CD markers, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 36 "bone marrow: 204.8" "Cell type enriched" "Detected in some" 13 "Neutrophil progenitors: 1216.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "neutrophil: 1.6;non-classical monocyte: 1.1" "Group enriched" "Detected in many" 6 "granulocytes: 1.6;monocytes: 1.1" "Not detected" "Not detected" "Liver - Erythroid cells, Lung - Neutrophils_1, Pituitary gland - Neutrophils, Spleen - Neutrophils_1" "CAB033676, CAB080307" Enhanced "Intracellular and membrane" "Cell adhesion" NA NA 540000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 15: Bone marrow - Innate immune response" "Cluster 34: Non-specific - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 6 "CAB033676: , CAB080307: " "unprognostic (1.38e-3)" "unprognostic (5.34e-2)" "unprognostic (1.22e-1)" "unprognostic (9.43e-2)" CEBPA "C/EBP-alpha, CEBP" ENSG00000245848 "CCAAT enhancer binding protein alpha" P49715 19 33299934-33302534 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "adipose tissue: 92.7;breast: 67.7;liver: 198.2;skin 1: 115.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 83.8;Cholangiocytes: 70.1;Colonocytes: 75.8;Hepatocytes: 110.7;Hofbauer cells: 113.5;Microglia: 87.3;Monocyte progenitors: 69.5;Suprabasal keratinocytes: 129.4;Syncytiotrophoblasts: 278.4" "Cell type enriched" "Detected in many" 5 "central nervous system macrophage: 104.2" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 171.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 16.1;classical monocyte: 7.1;intermediate monocyte: 12.3;myeloid DC: 5.1;non-classical monocyte: 15.8" "Group enriched" "Detected in many" 15 "dendritic cells: 5.1;granulocytes: 16.1;monocytes: 15.8" "Cancer enhanced" "Detected in many" "Leukemia: 73.6;liver cancer: 63.7" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Stomach - Chief cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052734, HPA065037, HPA067937" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 138 Nucleoplasm Vesicles "HPA052734: , HPA065037: , HPA067937: " "unprognostic (1.12e-1)" "unprognostic (2.78e-1)" "unprognostic (4.93e-2)" "unprognostic (1.21e-2)" "unprognostic (5.06e-3)" "unprognostic (5.81e-2)" "unprognostic (1.32e-1)" "unprognostic (1.97e-2)" "unprognostic (8.48e-2)" "unprognostic (7.15e-2)" "unprognostic (7.66e-2)" "unprognostic (2.14e-1)" "unprognostic (2.33e-3)" "unprognostic (1.97e-1)" "unprognostic (7.83e-2)" "potential prognostic favorable (2.96e-4)" "unprognostic (1.52e-1)" "unprognostic (6.32e-2)" "unprognostic (6.36e-3)" "unprognostic (7.45e-2)" "unprognostic (7.56e-3)" "unprognostic (1.76e-1)" "unprognostic (7.65e-2)" "unprognostic (1.54e-1)" "unprognostic (1.99e-3)" "unprognostic (3.66e-1)" "unprognostic (1.08e-1)" "unprognostic (1.76e-1)" "unprognostic (3.74e-1)" "unprognostic (6.66e-2)" "unprognostic (3.87e-2)" CEBPB "C/EBP-beta, CRP2, IL6DBP, LAP, NFIL6, TCF5" ENSG00000172216 "CCAAT enhancer binding protein beta" P17676 20 50190830-50192668 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 983.3;monocytes: 936.4;Neutrophils: 2591.5;Syncytiotrophoblasts: 1822.8" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 136.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 16.8" "Group enriched" "Detected in many" 8 "granulocytes: 16.8;monocytes: 7.7" "Low cancer specificity" "Detected in all" "Colon - Neutrophils, Spleen - Neutrophils_2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB004213, HPA061355, HPA062267" Supported Enhanced Nucleoplasm Yes No "Cluster 45: Eosinophils - Unknown function" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 39: Astrocytes - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 82 Nucleoplasm "CAB004213: , HPA061355: , HPA062267: " "unprognostic (7.51e-2)" "unprognostic (4.17e-2)" "unprognostic (1.38e-2)" "unprognostic (3.49e-2)" "unprognostic (1.66e-2)" "unprognostic (3.69e-2)" "unprognostic (1.29e-2)" "unprognostic (1.80e-3)" "unprognostic (1.12e-2)" "unprognostic (1.43e-1)" "potential prognostic unfavorable (1.63e-6)" "unprognostic (3.46e-2)" "unprognostic (3.29e-3)" "unprognostic (1.95e-1)" "unprognostic (1.75e-1)" "unprognostic (6.39e-3)" "unprognostic (6.95e-2)" "unprognostic (2.33e-3)" "unprognostic (6.25e-3)" "unprognostic (7.59e-3)" "unprognostic (1.15e-1)" "unprognostic (1.79e-3)" "unprognostic (2.08e-3)" "unprognostic (6.58e-2)" "unprognostic (3.83e-1)" "unprognostic (1.20e-2)" "unprognostic (2.73e-2)" "unprognostic (1.30e-2)" "unprognostic (1.14e-1)" "unprognostic (9.91e-3)" "unprognostic (2.55e-1)" CEBPD "C/EBP-delta, CELF, CRP3, NF-IL6-beta" ENSG00000221869 "CCAAT enhancer binding protein delta" P49716 8 47736913-47738164 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal basal cells: 1717.2;Fallopian secretory cells: 1552.6;Neutrophils: 1639.8;Pericytes: 1319.6;Smooth muscle cells: 1324.7" "Cell type enhanced" "Detected in many" "endothelial cell: 186.9;vascular associated smooth muscle cell: 230.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 55.1" "Group enriched" "Detected in many" 5 "granulocytes: 55.1;monocytes: 19.9" "Low cancer specificity" "Detected in all" "Colon - Neutrophils, Testis - Endothelial cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA067581 Approved Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 39: Astrocytes - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 103: Non-specific - Basic cellular processes" 13 Nucleoplasm "HPA067581: " "potential prognostic favorable (1.87e-4)" "potential prognostic favorable (3.33e-4)" "unprognostic (2.75e-3)" "unprognostic (3.87e-2)" "unprognostic (2.20e-1)" "unprognostic (1.22e-2)" "unprognostic (6.68e-3)" "potential prognostic unfavorable (9.94e-4)" "unprognostic (1.62e-2)" "potential prognostic favorable (9.19e-4)" "unprognostic (7.23e-3)" "unprognostic (2.20e-1)" "unprognostic (2.42e-2)" "unprognostic (4.05e-2)" "unprognostic (7.58e-2)" "unprognostic (7.16e-2)" "unprognostic (1.81e-2)" "unprognostic (1.45e-1)" "unprognostic (1.97e-1)" "unprognostic (1.12e-2)" "unprognostic (2.22e-1)" "unprognostic (1.01e-1)" "unprognostic (2.17e-1)" "unprognostic (3.52e-1)" "unprognostic (1.04e-1)" "potential prognostic favorable (5.54e-5)" "unprognostic (1.62e-1)" "unprognostic (1.47e-2)" "unprognostic (8.26e-2)" "unprognostic (2.14e-1)" "unprognostic (7.94e-2)" CEBPE CRP1 ENSG00000092067 "CCAAT enhancer binding protein epsilon" Q15744 14 23117036-23120256 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "bone marrow: 43.6" "Cell type enriched" "Detected in some" 8 "Neutrophil progenitors: 94.0" "Cell type enriched" "Detected in single" 20 "central nervous system macrophage: 2.9" "Cancer enhanced" "Detected in single" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 1.0" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 271 "eosinophil: 504.5" "Lineage enriched" "Detected in many" 341 "granulocytes: 504.5" "Group enriched" "Detected in some" 16 "Leukemia: 17.5;lymphoma: 5.5" "Lung - Neutrophils_1, Spleen - Neutrophils_1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA002928, CAB005113" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 15 Nucleoplasm "Plasma membrane, Cytosol" "CAB005113: , HPA002928: " "unprognostic (3.25e-1)" "unprognostic (7.33e-3)" CEBPG "GPE1BP, IG/EBP-1" ENSG00000153879 "CCAAT enhancer binding protein gamma" P53567 19 33373685-33382686 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 177.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012024 Enhanced Supported Nucleoplasm NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 31 Nucleoplasm "HPA012024: " "unprognostic (9.79e-3)" "unprognostic (1.75e-2)" "unprognostic (1.25e-1)" "unprognostic (2.06e-1)" "unprognostic (3.94e-2)" "unprognostic (6.26e-2)" "unprognostic (3.96e-2)" "unprognostic (3.11e-2)" "unprognostic (2.90e-1)" "unprognostic (8.55e-2)" "potential prognostic favorable (2.93e-4)" "unprognostic (1.08e-1)" "unprognostic (2.60e-2)" "unprognostic (1.19e-1)" "unprognostic (3.48e-1)" "unprognostic (5.04e-2)" "unprognostic (1.05e-1)" "unprognostic (2.53e-2)" "unprognostic (1.14e-3)" "unprognostic (2.57e-1)" "unprognostic (1.59e-1)" "unprognostic (3.65e-2)" "unprognostic (6.70e-2)" "unprognostic (5.17e-2)" "unprognostic (4.65e-3)" "unprognostic (5.96e-2)" "unprognostic (1.61e-1)" "unprognostic (3.61e-2)" "unprognostic (1.15e-1)" "unprognostic (1.05e-2)" "unprognostic (2.36e-3)" CEBPZ "CBF2, CTF2" ENSG00000115816 "CCAAT enhancer binding protein zeta" Q03701 2 37201612-37231596 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 501.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052065 Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 17: Non-specific - RNA processing" 57 Nucleoplasm Vesicles "HPA052065: " "unprognostic (2.28e-1)" "unprognostic (1.38e-2)" "unprognostic (3.72e-1)" "unprognostic (6.69e-3)" "unprognostic (6.50e-2)" "unprognostic (2.88e-1)" "unprognostic (4.15e-1)" "unprognostic (6.45e-2)" "unprognostic (5.39e-2)" "unprognostic (1.16e-3)" "potential prognostic favorable (1.61e-7)" "unprognostic (5.25e-3)" "unprognostic (2.78e-2)" "validated prognostic unfavorable (9.55e-4)" "validated prognostic unfavorable (3.26e-4)" "unprognostic (9.39e-2)" "unprognostic (2.89e-2)" "unprognostic (9.82e-3)" "unprognostic (1.30e-1)" "unprognostic (1.44e-1)" "unprognostic (3.60e-2)" "unprognostic (1.40e-2)" "potential prognostic unfavorable (4.28e-5)" "unprognostic (1.27e-2)" "potential prognostic favorable (2.48e-4)" "unprognostic (1.43e-2)" "unprognostic (6.40e-3)" "unprognostic (6.23e-2)" "unprognostic (1.81e-1)" "unprognostic (7.19e-2)" "unprognostic (1.52e-1)" CEBPZOS CEBPZ-AS1 ENSG00000218739 "CEBPZ opposite strand" A8MTT3 2 37196488-37216193 "Essential proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053866 Uncertain Approved Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 48: Neutrophils - Phagocytosis & degranulation" Nucleoplasm "HPA053866: " "unprognostic (1.22e-2)" "unprognostic (2.75e-3)" "unprognostic (7.86e-3)" "unprognostic (1.53e-1)" "unprognostic (7.92e-2)" "unprognostic (2.80e-2)" "unprognostic (2.37e-3)" "unprognostic (4.71e-3)" "unprognostic (2.49e-3)" "unprognostic (6.91e-2)" "unprognostic (7.93e-2)" "unprognostic (1.38e-1)" "potential prognostic unfavorable (1.67e-7)" "unprognostic (5.71e-2)" "unprognostic (1.43e-1)" "potential prognostic favorable (9.34e-5)" "unprognostic (1.83e-2)" "unprognostic (4.58e-1)" "unprognostic (4.68e-3)" "unprognostic (1.09e-2)" "unprognostic (3.62e-3)" "unprognostic (1.51e-1)" "unprognostic (1.62e-1)" "unprognostic (3.92e-2)" "unprognostic (1.19e-2)" "unprognostic (3.66e-2)" "unprognostic (2.73e-1)" "unprognostic (4.15e-2)" "unprognostic (1.06e-2)" CECR2 KIAA1740 ENSG00000099954 "CECR2 histone acetyl-lysine reader" Q9BXF3 22 17359949-17558151 "Essential proteins, Predicted intracellular proteins" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.1;retina: 11.8;skeletal muscle: 18.3" "Cell type enhanced" "Detected in many" "Bergmann glia: 245.5;Cone photoreceptor cells: 705.9;Myonuclei: 799.8;Pituicytes/FSCs: 275.9;Pituitary stem cells: 508.5;Podocytes: 251.9;Rod photoreceptor cells: 365.8;Somatotrophs: 254.0;Syncytiotrophoblasts: 287.9;Thymic myoid cells: 299.1" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 6 "Testicular Germ Cell Tumor (TCGA): 16.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 6.8" "Colon - Enteric glia cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA002943 Approved Approved Nucleoplasm,Vesicles No No "Cluster 25: Non-specific - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 9 Nucleoplasm Vesicles "HPA002943: " "unprognostic (3.03e-1)" "unprognostic (2.03e-2)" "unprognostic (4.95e-2)" "unprognostic (2.47e-1)" "unprognostic (1.75e-2)" "unprognostic (2.24e-3)" "unprognostic (2.26e-1)" "unprognostic (6.38e-3)" "unprognostic (1.57e-1)" "unprognostic (1.62e-1)" "unprognostic (1.17e-1)" "unprognostic (7.14e-2)" "unprognostic (1.96e-1)" "unprognostic (2.33e-1)" "unprognostic (2.36e-1)" CEL "BSSL, MODY8" ENSG00000170835 "Carboxyl ester lipase" P19835 9 133061981-133071861 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Serine esterase" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 550 "pancreas: 104264.8" "Cell type enriched" "Detected in many" 4 "Pancreatic acinar cells: 18122.0" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in many" 22 "Pancreatic Adenocarcinoma (TCGA): 1018.6" "Region enriched" "Detected in all" 4 "choroid plexus: 24.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 16.1" "Pancreas - Exocrine glandular cells, Pituitary gland - Corticotropes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA008023, HPA052701" Enhanced "Secreted to digestive system" Enzyme NA NA 180000 "Cluster 8: Pancreas - Proteolysis" "Cluster 23: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 5: Pancreatic acinar cells - Pancreatic exocrine secretion" "HPA008023: , HPA052701: " "unprognostic (4.51e-2)" "potential prognostic unfavorable (6.68e-4)" "unprognostic (5.27e-2)" "unprognostic (2.83e-2)" "unprognostic (6.07e-2)" "unprognostic (7.04e-3)" "unprognostic (2.93e-1)" "unprognostic (1.46e-3)" "unprognostic (2.32e-1)" "unprognostic (1.99e-1)" "potential prognostic unfavorable (3.08e-6)" "unprognostic (1.17e-2)" "unprognostic (7.90e-2)" "unprognostic (5.46e-3)" "unprognostic (1.21e-1)" "unprognostic (5.78e-1)" "unprognostic (6.33e-2)" "unprognostic (4.57e-2)" "unprognostic (4.81e-2)" "unprognostic (2.11e-1)" "potential prognostic unfavorable (1.23e-4)" "unprognostic (5.04e-2)" "unprognostic (2.92e-1)" "unprognostic (1.02e-1)" "unprognostic (7.82e-2)" "unprognostic (3.27e-1)" "unprognostic (1.52e-1)" CELA1 ELA1 ENSG00000139610 "Chymotrypsin like elastase 1" Q9UNI1 12 51328442-51346679 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "adrenal gland: 2.2;pancreas: 6.2" "Cell type enhanced" "Detected in some" "Extravillous trophoblasts: 5.7;Kupffer cells: 12.3;Macrophages: 1.7;Monocyte progenitors: 2.2;monocytes: 2.7;Neutrophils: 1.6;Platelets: 4.2;Thymocytes: 1.7;Undifferentiated spermatogonia: 3.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "basophil: 12.6;naive CD4 T-cell: 12.3" "Group enriched" "Detected in many" 8 "granulocytes: 12.6;T-cells: 12.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Secreted - unknown location" Enzyme NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 8: Pancreas - Proteolysis" "Cluster 34: Testis cancer - Unknown function" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" CELA2A ELA2A ENSG00000142615 "Chymotrypsin like elastase 2A" P08217 1 15456728-15472091 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Diabetes mellitus, Disease variant, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5457 "pancreas: 153459.5" "Cell type enriched" "Detected in some" 130 "Pancreatic acinar cells: 1882.2" "Cell type enhanced" "Detected in single" "upper rhombic lip: 1.4" "Cancer enriched" "Detected in single" 6560 "Pancreatic Adenocarcinoma (TCGA): 1689.9" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Exocrine glandular cells" "Secreted to digestive system" Enzyme NA NA 7900000 "Cluster 8: Pancreas - Proteolysis" "Cluster 37: Neurons - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 5: Pancreatic acinar cells - Pancreatic exocrine secretion" 3 "unprognostic (3.71e-2)" "unprognostic (4.13e-2)" CELA2B "ELA2B, RP11-265F14.2" ENSG00000215704 "Chymotrypsin like elastase 2B" P08218 1 15465909-15491395 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 3915 "pancreas: 19273.2" "Cell type enriched" "Detected in many" 22 "Pancreatic acinar cells: 2208.9" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in single" 316 "Pancreatic Adenocarcinoma (TCGA): 222.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Exocrine glandular cells" "Secreted to digestive system" Enzyme NA NA 9300000 "Cluster 46: Basophils - Proteolysis" "Cluster 8: Pancreas - Proteolysis" "Cluster 37: Neurons - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 5: Pancreatic acinar cells - Pancreatic exocrine secretion" 14 "unprognostic (1.36e-1)" "unprognostic (7.03e-2)" CELA3A "ELA3, ELA3A" ENSG00000142789 "Chymotrypsin like elastase 3A" P09093 1 22001657-22012542 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5205 "pancreas: 247619.6" "Cell type enriched" "Detected in some" 177 "Pancreatic acinar cells: 13936.7" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 2565 "Pancreatic Adenocarcinoma (TCGA): 3639.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Exocrine glandular cells" "HPA028086, HPA045650" Supported Approved Cytosol "Secreted to digestive system" Enzyme NA NA 770000 "Cluster 8: Pancreas - Proteolysis" "Cluster 15: Kidney cancer - Membrane components" "Cluster 5: Pancreatic acinar cells - Pancreatic exocrine secretion" 14 Cytosol "HPA028086: , HPA045650: " "unprognostic (2.20e-3)" "unprognostic (5.95e-2)" "unprognostic (1.84e-3)" "unprognostic (2.49e-2)" CELA3B "CBPP, ELA3B" ENSG00000219073 "Chymotrypsin like elastase 3B" P08861 1 21977022-21998642 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 2938 "pancreas: 46793.9" "Cell type enriched" "Detected in some" 29 "Pancreatic acinar cells: 1221.4" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 1419 "Pancreatic Adenocarcinoma (TCGA): 1120.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Exocrine glandular cells, Stomach - Chief cells, Testis - Late spermatids" "HPA028086, HPA045650" Supported Approved Cytosol "Secreted to digestive system" Enzyme NA NA 720000 "Cluster 8: Pancreas - Proteolysis" "Cluster 5: Rhabdoid - Unknown function" "Cluster 5: Pancreatic acinar cells - Pancreatic exocrine secretion" 3 Cytosol "HPA028086: , HPA045650: " "unprognostic (5.30e-2)" "unprognostic (1.23e-2)" CELF1 "BRUNOL2, CUG-BP, CUGBP, CUGBP1, EDEN-BP, hNab50, NAB50, NAPOR" ENSG00000149187 "CUGBP Elav-like family member 1" Q92879 11 47465933-47565569 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Activator, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 636.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016114, HPA044597, CAB069989" Supported Enhanced Nucleoplasm NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 15: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 14 Nucleoplasm "CAB016114: , CAB069989: , HPA044597: " "unprognostic (3.03e-2)" "unprognostic (4.62e-2)" "unprognostic (3.08e-1)" "unprognostic (1.16e-2)" "unprognostic (6.98e-2)" "unprognostic (1.30e-1)" "unprognostic (1.90e-1)" "unprognostic (4.07e-3)" "unprognostic (1.68e-2)" "unprognostic (1.53e-3)" "potential prognostic favorable (6.75e-4)" "unprognostic (6.08e-3)" "unprognostic (2.13e-1)" "potential prognostic unfavorable (5.16e-4)" "unprognostic (1.49e-1)" "unprognostic (3.21e-1)" "unprognostic (5.41e-3)" "unprognostic (2.64e-1)" "unprognostic (1.59e-1)" "unprognostic (2.43e-1)" "unprognostic (1.24e-3)" "unprognostic (1.58e-1)" "unprognostic (7.95e-3)" "unprognostic (1.67e-2)" "unprognostic (8.05e-2)" "unprognostic (1.38e-2)" "unprognostic (7.63e-2)" "unprognostic (1.99e-1)" "unprognostic (3.30e-1)" "unprognostic (1.73e-1)" "unprognostic (4.01e-2)" CELF2 "BRUNOL3, CUGBP2, Etr-3, NAPOR-2" ENSG00000048740 "CUGBP Elav-like family member 2" O95319 10 10798397-11336675 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "mRNA processing" "Repressor, RNA-binding" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 73.5" "Cell type enhanced" "Detected in many" "Adipocytes: 1537.5;Brain excitatory neurons: 2017.3;Brain inhibitory neurons: 1668.3;Neutrophil progenitors: 2527.5;Neutrophils: 3802.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 73.4;Myeloma: 50.4" "Minor Salivary Gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016395, HPA035813" Enhanced Supported "Nucleoplasm,Vesicles,Midbody ring" Yes No "Cluster 35: Neutrophils - Protein binding" "Cluster 61: Non-specific - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 2 Nucleoplasm "Vesicles, Midbody ring" "CAB016395: , HPA035813: " "unprognostic (5.92e-3)" "unprognostic (6.94e-2)" "unprognostic (2.26e-2)" "unprognostic (3.34e-2)" "unprognostic (2.41e-2)" "unprognostic (1.24e-1)" "unprognostic (9.21e-2)" "unprognostic (4.02e-3)" "unprognostic (1.66e-3)" "unprognostic (5.22e-2)" "potential prognostic favorable (6.10e-4)" "unprognostic (3.02e-1)" "unprognostic (1.61e-1)" "unprognostic (7.82e-2)" "unprognostic (4.63e-2)" "unprognostic (1.20e-2)" "unprognostic (3.97e-2)" "unprognostic (1.20e-1)" "unprognostic (2.06e-1)" "unprognostic (4.29e-2)" "unprognostic (6.72e-2)" "unprognostic (7.14e-2)" "unprognostic (3.72e-2)" "unprognostic (1.59e-1)" "unprognostic (1.13e-1)" "unprognostic (7.03e-2)" "unprognostic (2.31e-1)" "unprognostic (1.49e-1)" "unprognostic (1.94e-1)" "unprognostic (2.07e-2)" "unprognostic (4.08e-1)" CELF3 "BRUNOL1, CAGH4, ERDA4, MGC57297, TNRC4" ENSG00000159409 "CUGBP Elav-like family member 3" Q5SZQ8 1 151700058-151716803 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Activator, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 99.3;pituitary gland: 104.6" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 74.5;Brain excitatory neurons: 31.4;Brain inhibitory neurons: 37.5;Cone photoreceptor cells: 43.5;Corticotrophs: 23.7;Gonadotrophs: 22.1;Lactotrophs: 86.0;Neuroendocrine cells: 54.6;Other brain neurons: 37.2;Pancreatic islet cells: 36.4;Retinal amacrine cells: 22.4;Retinal bipolar cells: 101.3;Somatotrophs: 39.2;Thyrotrophs: 53.2" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Glioblastoma Multiforme (TCGA): 11.2;Pancreatic Adenocarcinoma (TCGA): 9.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "Neuroblastoma: 66.0" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Pituitary gland - Lactotropes, Stomach - Gastric enteroendocrine cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Parafollicular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006292 Uncertain Approved Nucleoplasm NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" Nucleoplasm "HPA006292: " "unprognostic (1.15e-1)" "unprognostic (9.36e-2)" "unprognostic (1.95e-2)" "unprognostic (7.75e-2)" "unprognostic (4.24e-3)" "unprognostic (8.25e-2)" "unprognostic (1.94e-2)" "unprognostic (1.64e-3)" "unprognostic (1.76e-1)" "unprognostic (4.81e-2)" "unprognostic (1.17e-1)" "unprognostic (1.86e-1)" "unprognostic (1.20e-1)" CELF4 BRUNOL4 ENSG00000101489 "CUGBP Elav-like family member 4" Q9BZC1 18 37243040-37565827 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Activator, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 94.3;pituitary gland: 26.9" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 265.9;Brain excitatory neurons: 341.9;Brain inhibitory neurons: 367.3;Corticotrophs: 186.3;Lactotrophs: 271.7;Other brain neurons: 372.4;Retinal amacrine cells: 865.3;Retinal ganglion cells: 177.7;Retinal horizontal cells: 412.7;Somatotrophs: 367.0;Thyrotrophs: 279.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "lung cancer: 7.9;Neuroblastoma: 14.3" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013322, HPA037986" Enhanced Supported Nucleoplasm NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 1: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 109: Neurons - Neuronal signaling" Nucleoplasm "HPA013322: , HPA037986: " "unprognostic (2.19e-1)" "unprognostic (1.19e-1)" "unprognostic (2.52e-1)" "unprognostic (2.00e-3)" "unprognostic (3.48e-2)" "unprognostic (9.35e-3)" "unprognostic (3.73e-1)" "unprognostic (8.27e-3)" "unprognostic (3.25e-3)" "unprognostic (2.01e-1)" "unprognostic (2.22e-1)" "unprognostic (2.14e-1)" "unprognostic (1.23e-1)" "unprognostic (1.04e-2)" "unprognostic (3.24e-2)" "unprognostic (5.46e-3)" "unprognostic (2.59e-2)" "unprognostic (5.27e-2)" "unprognostic (2.99e-1)" "unprognostic (4.26e-1)" "potential prognostic unfavorable (1.68e-5)" CELF5 BRUNOL5 ENSG00000161082 "CUGBP Elav-like family member 5" Q8N6W0 19 3224661-3297076 "Predicted intracellular proteins" "mRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 23.2" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 147.9;Brain inhibitory neurons: 191.0;Oligodendrocyte progenitor cells: 43.5;Other brain neurons: 145.5;Retinal amacrine cells: 185.2;Retinal bipolar cells: 141.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 3.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 5.7" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042012, HPA060336" Enhanced Supported NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" 20 "HPA042012: , HPA060336: " "unprognostic (1.60e-1)" "unprognostic (2.74e-1)" "unprognostic (1.30e-3)" "unprognostic (2.94e-1)" "unprognostic (5.80e-2)" "unprognostic (1.40e-1)" CELF6 BRUNOL6 ENSG00000140488 "CUGBP Elav-like family member 6" Q96J87 15 72284727-72320157 "Predicted intracellular proteins" "mRNA processing" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.6" "Cell type enhanced" "Detected in some" "Astrocytes: 1.1;Brain excitatory neurons: 1.0;Other brain neurons: 3.0" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 2.4" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046985, HPA053526" Uncertain NA NA "Cluster 64: Non-specific - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 98: Neurons - Neurotransmission & signaling" 1 "HPA046985: , HPA053526: " "unprognostic (3.68e-2)" "potential prognostic unfavorable (4.37e-4)" "potential prognostic unfavorable (2.00e-4)" "unprognostic (9.44e-3)" "unprognostic (7.54e-2)" "unprognostic (6.45e-2)" "unprognostic (8.12e-2)" "unprognostic (5.05e-2)" "unprognostic (1.03e-2)" "unprognostic (3.58e-2)" "unprognostic (2.98e-2)" "potential prognostic favorable (4.57e-4)" "unprognostic (8.24e-3)" "unprognostic (1.24e-1)" "unprognostic (1.92e-2)" "unprognostic (1.65e-1)" "unprognostic (1.75e-1)" "unprognostic (9.31e-2)" CELSR1 "ADGRC1, CDHF9, FMI2, HFMI2, ME2" ENSG00000075275 "Cadherin EGF LAG seven-pass G-type receptor 1" Q9NYQ6 22 46360834-46537620 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 32.9" "Cell type enhanced" "Detected in many" "Endometrial luminal cells: 130.5;Esophageal apical cells: 133.4;Ocular epithelial cells: 169.8;Proximal tubule cells: 159.4;Respiratory basal cells: 211.2;Respiratory ciliated cells: 255.3;Respiratory deuterosomal cells: 218.7;Respiratory secretory cells: 211.3;Transitional alveolar cells: 126.7" "Cell type enriched" "Detected in many" 14 "ependymal cell: 110.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "memory B-cell: 2.2;naive B-cell: 1.9" "Lineage enriched" "Detected in single" 6 "B-cells: 2.2" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary gland basal cells, Pituitary gland - Corticotropes, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA052976, HPA060521" Enhanced "Nucleoplasm,Plasma membrane" "Intracellular and membrane" Receptor NA NA 260000 "Cluster 34: B-cells - Unknown function" "Cluster 58: Skin - Keratinization" "Cluster 46: Brainstem - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 100: Stratified epithelial cells - Barrier functions" 1 "Plasma membrane" Nucleoplasm "HPA052976: , HPA060521: " "unprognostic (5.85e-2)" "unprognostic (1.46e-1)" "unprognostic (1.31e-1)" "unprognostic (1.68e-1)" "unprognostic (6.21e-2)" "unprognostic (6.04e-2)" "unprognostic (4.44e-1)" "unprognostic (3.76e-2)" "unprognostic (5.35e-2)" "unprognostic (5.78e-2)" "unprognostic (4.08e-3)" "unprognostic (2.97e-2)" "unprognostic (1.39e-3)" "unprognostic (3.28e-1)" "potential prognostic favorable (9.21e-5)" "unprognostic (5.96e-2)" "unprognostic (2.11e-2)" "unprognostic (1.36e-1)" "unprognostic (2.38e-1)" "unprognostic (7.38e-3)" "unprognostic (6.76e-2)" "unprognostic (1.98e-2)" "potential prognostic unfavorable (1.28e-5)" "unprognostic (3.41e-2)" "unprognostic (2.91e-1)" "unprognostic (2.15e-1)" "unprognostic (3.22e-1)" "unprognostic (3.13e-2)" "unprognostic (1.75e-1)" "unprognostic (8.27e-2)" "unprognostic (4.10e-3)" CELSR2 "ADGRC2, CDHF10, EGFL2, Flamingo1, KIAA0279, MEGF3" ENSG00000143126 "Cadherin EGF LAG seven-pass G-type receptor 2" Q9HCU4 1 109249539-109275751 "Essential proteins, G-protein coupled receptors, Predicted membrane proteins" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.4;skin 1: 23.4" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 71.8;Fallopian secretory cells: 43.0;Oligodendrocytes: 49.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013952 Uncertain Uncertain Vesicles,Cytosol NA NA 8200000 "Cluster 2: Non-specific - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 35: Neurons - Synaptic function & neurogenesis" 30 Cytosol Vesicles "HPA013952: " "unprognostic (3.94e-1)" "unprognostic (2.48e-2)" "unprognostic (5.12e-1)" "unprognostic (2.47e-1)" "unprognostic (2.08e-2)" "unprognostic (1.54e-1)" "unprognostic (9.66e-2)" "unprognostic (1.61e-1)" "unprognostic (1.21e-1)" "unprognostic (6.03e-2)" "potential prognostic favorable (7.34e-7)" "unprognostic (3.41e-2)" "unprognostic (2.21e-1)" "unprognostic (1.38e-1)" "unprognostic (1.67e-1)" "unprognostic (2.46e-2)" "unprognostic (3.68e-1)" "unprognostic (2.43e-2)" "unprognostic (1.53e-2)" "unprognostic (9.35e-2)" "unprognostic (3.36e-2)" "unprognostic (4.60e-2)" "unprognostic (3.15e-1)" "unprognostic (1.52e-2)" "unprognostic (1.05e-1)" "unprognostic (1.91e-1)" "unprognostic (8.14e-2)" "unprognostic (2.10e-1)" "unprognostic (3.10e-2)" "unprognostic (2.57e-1)" CELSR3 "ADGRC3, CDHF11, EGFL1, FMI1, HFMI1, MEGF2" ENSG00000008300 "Cadherin EGF LAG seven-pass G-type receptor 3" Q9NYQ7 3 48636463-48662886 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 15.4;pituitary gland: 6.8" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 10.6;Brain excitatory neurons: 12.4;Brain inhibitory neurons: 13.2;Cone photoreceptor cells: 14.5;Corticotrophs: 11.3;Gonadotrophs: 14.5;Lactotrophs: 13.3;Other brain neurons: 11.2;Pancreatic islet cells: 12.5;Retinal amacrine cells: 13.2;Retinal bipolar cells: 10.6;Retinal horizontal cells: 18.0;Somatotrophs: 14.0;Thyrotrophs: 12.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal medulla cells, Pancreas - Alpha cells, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062866 Approved NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 15: Non-specific - Transcription" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 2 "HPA062866: " "unprognostic (1.47e-2)" "unprognostic (4.92e-2)" "unprognostic (3.13e-1)" "unprognostic (2.57e-2)" "unprognostic (1.37e-1)" "unprognostic (5.64e-2)" "unprognostic (1.75e-1)" "potential prognostic favorable (3.61e-4)" "unprognostic (3.97e-3)" "unprognostic (7.55e-2)" "unprognostic (8.95e-3)" "unprognostic (3.67e-2)" "unprognostic (3.85e-2)" "unprognostic (1.91e-1)" "unprognostic (2.11e-3)" "unprognostic (1.30e-1)" "unprognostic (2.40e-1)" "unprognostic (5.05e-1)" CEMIP "HYBID, IR2155535, KIAA1199, TMEM2L" ENSG00000103888 "Cell migration inducing hyaluronidase 1" Q8WUJ3 15 80779343-80951776 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 30.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 164.0;Choroid plexus epithelial cells: 220.5;Epicardial cells: 275.2;Esophageal apical cells: 257.4;Fibro-adipogenic progenitors: 124.7;Fibroblasts: 275.4;Mesothelial cells: 128.1;Ocular epithelial cells: 231.0;Respiratory basal cells: 221.0" "Cell type enriched" "Detected in all" 18 "fibroblast: 5459.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Gastric cancer: 60.2" "Pituitary gland - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA079449 Supported "Nuclear membrane,Nucleoli fibrillar center,Endoplasmic reticulum" "Secreted in other tissues" Enzyme NA NA 1900000 "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 22: Non-specific - Basic cellular functions" 4 "Nucleoli fibrillar center" "Nuclear membrane, Endoplasmic reticulum" "HPA079449: " "unprognostic (2.04e-1)" "unprognostic (5.73e-3)" "unprognostic (5.14e-2)" "unprognostic (1.59e-1)" "unprognostic (2.20e-2)" "unprognostic (1.96e-3)" "unprognostic (1.64e-3)" "unprognostic (5.13e-2)" "unprognostic (6.19e-3)" "potential prognostic unfavorable (1.18e-4)" "unprognostic (1.04e-1)" "potential prognostic unfavorable (4.98e-4)" "unprognostic (1.45e-1)" "unprognostic (1.03e-3)" "unprognostic (3.43e-2)" "unprognostic (1.14e-2)" "unprognostic (7.95e-3)" "unprognostic (1.48e-1)" "unprognostic (6.43e-2)" "unprognostic (3.18e-2)" "unprognostic (8.46e-2)" "unprognostic (3.16e-2)" "unprognostic (2.59e-1)" "unprognostic (4.08e-1)" "unprognostic (1.14e-1)" "unprognostic (3.88e-2)" "unprognostic (4.66e-2)" "unprognostic (4.25e-2)" "unprognostic (2.02e-2)" CEMIP2 TMEM2 ENSG00000135048 "Cell migration inducing hyaluronidase 2" Q9UHN6 9 71683366-71816690 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Developmental protein, Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 87.0;placenta: 74.8" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 761.6;NK-cells: 1572.1;T-cells: 945.5" "Cell type enhanced" "Detected in all" "endothelial cell: 778.3;leukocyte: 411.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017080, HPA044889" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA 130000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 29: Forebrain - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 7 "Plasma membrane" "Vesicles, Cytosol" "HPA017080: , HPA044889: " "unprognostic (1.28e-1)" "unprognostic (2.31e-1)" "unprognostic (3.43e-2)" "unprognostic (1.42e-1)" "unprognostic (8.38e-2)" "unprognostic (8.69e-2)" "unprognostic (1.65e-2)" "unprognostic (6.40e-2)" "unprognostic (1.13e-1)" "potential prognostic favorable (5.78e-7)" "unprognostic (7.72e-3)" "unprognostic (1.22e-2)" "unprognostic (5.45e-2)" "unprognostic (2.94e-1)" "unprognostic (3.07e-2)" "unprognostic (6.16e-2)" "unprognostic (2.60e-1)" "unprognostic (5.22e-2)" "unprognostic (2.24e-2)" "potential prognostic unfavorable (6.07e-4)" "unprognostic (1.01e-1)" "unprognostic (6.48e-2)" "unprognostic (7.24e-2)" "unprognostic (1.01e-1)" "unprognostic (3.08e-1)" "unprognostic (1.03e-1)" "unprognostic (1.84e-1)" "unprognostic (7.57e-3)" "unprognostic (1.03e-1)" CEMP1 CP-23 ENSG00000205923 "Cementum protein 1" Q6PRD7 16 2530035-2531417 "Metabolic proteins, Predicted intracellular proteins" Differentiation "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 9.1;Early spermatids: 4.1;Epicardial cells: 20.5;Late spermatids: 13.9;Macrophages: 3.9" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 7 "basophil: 1.9" "Lineage enriched" "Detected in single" 7 "granulocytes: 1.9" "Cancer enhanced" "Detected in single" "Bile duct cancer: 2.6" "HPA057658, HPA075926" Approved Approved Nucleoplasm NA NA "Cluster 68: Non-specific - Basic cellular processes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 1 Nucleoplasm "HPA057658: , HPA075926: " "unprognostic (2.30e-1)" "unprognostic (1.26e-1)" "unprognostic (2.76e-2)" "unprognostic (3.45e-2)" "unprognostic (2.13e-1)" "unprognostic (8.08e-2)" "unprognostic (2.47e-1)" "potential prognostic unfavorable (1.09e-5)" "unprognostic (8.53e-3)" "unprognostic (1.84e-1)" "unprognostic (7.71e-2)" "unprognostic (7.80e-3)" "unprognostic (1.57e-1)" "unprognostic (1.66e-1)" "unprognostic (5.91e-3)" "unprognostic (1.61e-2)" "unprognostic (2.19e-2)" "unprognostic (6.44e-2)" "unprognostic (2.66e-1)" "unprognostic (4.26e-2)" "unprognostic (6.42e-3)" "unprognostic (3.71e-1)" "unprognostic (1.33e-1)" CENATAC "CCDC84, DLNB14" ENSG00000186166 "Centrosomal AT-AC splicing factor" Q86UT8 11 118998138-119015793 "Essential proteins, Human disease related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 63.8;Brain excitatory neurons: 65.9;Brain inhibitory neurons: 69.8;Choroid plexus epithelial cells: 203.0;Distal convoluted tubule cells: 91.6;Loop of henle epithelial cells: 66.7;Oligodendrocytes: 63.6;Podocytes: 70.7;Proximal tubule cells: 67.9;Renal collecting duct intercalated cells: 58.5;Renal connecting tubule cells: 85.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039906, HPA071715" Uncertain Approved Nucleoplasm No No "Cluster 30: Non-specific - DNA binding" "Cluster 64: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 24: Non-specific - Unknown function" "Cluster 102: Non-specific - Mixed function" 14 Nucleoplasm "HPA039906: , HPA071715: " "unprognostic (3.50e-2)" "unprognostic (4.29e-1)" "unprognostic (1.46e-1)" "unprognostic (1.99e-2)" "unprognostic (2.38e-1)" "unprognostic (5.99e-2)" "unprognostic (2.05e-3)" "unprognostic (1.06e-1)" "unprognostic (1.38e-3)" "potential prognostic unfavorable (8.77e-11)" "unprognostic (1.28e-1)" "unprognostic (9.11e-2)" "unprognostic (1.43e-2)" "unprognostic (4.89e-2)" "unprognostic (1.98e-1)" "unprognostic (2.27e-2)" "unprognostic (1.99e-1)" "unprognostic (1.62e-2)" "unprognostic (8.01e-3)" "unprognostic (3.88e-2)" "unprognostic (1.52e-3)" "unprognostic (4.70e-2)" "unprognostic (4.11e-2)" "unprognostic (5.57e-2)" "unprognostic (7.30e-3)" "unprognostic (1.32e-1)" "unprognostic (1.88e-1)" "unprognostic (7.60e-2)" "unprognostic (1.26e-1)" CEND1 "BM88, FLJ90066" ENSG00000184524 "Cell cycle exit and neuronal differentiation 1" Q8N111 11 787115-790113 "Predicted membrane proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 277.6" "Cell type enhanced" "Detected in some" "Astrocytes: 16.3;Brain excitatory neurons: 69.5;Brain inhibitory neurons: 53.3;Choroid plexus epithelial cells: 18.3;Corticotrophs: 20.9;Ependymal cells: 21.8;Gonadotrophs: 23.2;Oligodendrocyte progenitor cells: 28.5;Other brain neurons: 58.2;Retinal amacrine cells: 52.2;Retinal bipolar cells: 50.9;Retinal horizontal cells: 42.1" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" 9 "Glioblastoma Multiforme (TCGA): 41.7;Kidney Chromophobe (TCGA): 33.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 24.3;Rhabdoid: 27.0" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Kidney - Ascending Loop of Henle cells, Prostate - Smooth muscle cells, Spleen - Mitotic cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042527 Enhanced Supported Approved Mitochondria NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 72: Neuronal - Signal transduction" "Cluster 98: Neurons - Neurotransmission & signaling" 4 Mitochondria "HPA042527: " "unprognostic (8.68e-2)" "potential prognostic unfavorable (2.38e-5)" "unprognostic (1.72e-1)" "unprognostic (2.86e-1)" "unprognostic (1.89e-1)" "unprognostic (4.20e-2)" "potential prognostic favorable (3.27e-4)" "unprognostic (1.11e-3)" "unprognostic (1.72e-1)" "unprognostic (9.19e-3)" "unprognostic (1.96e-1)" CENPA "CenH3, CENP-A" ENSG00000115163 "Centromere protein A" P49450 2 26764289-26801067 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Host-virus interaction, Mitosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 12.4" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 50.3;Enteric transient amplifying cells: 43.9;Esophageal basal cells: 43.2;Extravillous trophoblasts: 36.8;Gastric progenitor cells: 67.9;Hofbauer cells: 35.7;Megakaryocyte progenitors: 36.3;Migrating cytotrophoblasts: 39.5;Monocyte progenitors: 68.5" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 32.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB008371, HPA073086" Enhanced Supported Nucleoplasm NA Yes "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Non-specific - Cell proliferation" 50 Nucleoplasm "CAB008371: , HPA073086: " "unprognostic (6.73e-3)" "unprognostic (7.88e-2)" "unprognostic (4.69e-1)" "unprognostic (1.07e-1)" "unprognostic (9.66e-3)" "unprognostic (5.94e-2)" "unprognostic (6.10e-2)" "unprognostic (1.18e-1)" "unprognostic (3.31e-2)" "potential prognostic unfavorable (2.66e-7)" "validated prognostic unfavorable (1.96e-10)" "validated prognostic unfavorable (1.70e-9)" "potential prognostic unfavorable (2.27e-5)" "unprognostic (4.46e-3)" "unprognostic (1.57e-2)" "unprognostic (7.30e-2)" "unprognostic (1.60e-1)" "unprognostic (1.58e-2)" "potential prognostic unfavorable (1.12e-5)" "unprognostic (2.59e-2)" "unprognostic (7.08e-2)" "unprognostic (7.52e-2)" "unprognostic (1.24e-2)" "unprognostic (2.91e-2)" "unprognostic (8.18e-2)" "unprognostic (3.73e-3)" CENPB ENSG00000125817 "Centromere protein B" P07199 20 3783851-3786740 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 169.8" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011626, HPA053507, HPA054405" Approved Enhanced "Nucleoplasm,Nuclear bodies" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 17: Non-specific - RNA processing" 9 "Nuclear bodies" Nucleoplasm "CAB011626: , HPA053507: , HPA054405: " "unprognostic (8.81e-2)" "unprognostic (1.96e-2)" "unprognostic (6.04e-2)" "unprognostic (7.69e-2)" "unprognostic (3.50e-2)" "unprognostic (1.82e-3)" "unprognostic (2.94e-1)" "unprognostic (2.46e-1)" "unprognostic (2.46e-1)" "unprognostic (1.20e-1)" "potential prognostic favorable (4.21e-4)" "unprognostic (2.82e-2)" "unprognostic (2.55e-1)" "validated prognostic unfavorable (5.19e-4)" "validated prognostic unfavorable (4.80e-4)" "unprognostic (8.45e-2)" "unprognostic (3.59e-2)" "unprognostic (3.82e-2)" "unprognostic (6.30e-2)" "unprognostic (2.11e-2)" "unprognostic (3.37e-1)" "unprognostic (8.93e-3)" "unprognostic (4.07e-2)" "unprognostic (6.61e-2)" "unprognostic (2.58e-1)" "potential prognostic favorable (5.61e-4)" "unprognostic (3.23e-1)" "unprognostic (4.05e-1)" "unprognostic (9.06e-2)" "unprognostic (4.03e-1)" "unprognostic (8.46e-2)" CENPC "CENP-C, CENPC1, hcp-4, MIF2" ENSG00000145241 "Centromere protein C" Q03188 4 67468762-67545503 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049740, HPA058252" Supported "Nucleoplasm,Nuclear bodies,Kinetochore,Midbody" Yes Yes "Cluster 24: Non-specific - Transcription" "Cluster 75: Ovary - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 16 "Nuclear bodies, Kinetochore" "Nucleoplasm, Midbody" "HPA049740: , HPA058252: " "unprognostic (5.84e-2)" "unprognostic (1.22e-2)" "unprognostic (2.09e-2)" "unprognostic (2.89e-1)" "unprognostic (4.61e-2)" "unprognostic (1.75e-1)" "unprognostic (3.94e-2)" "unprognostic (2.75e-1)" "validated prognostic favorable (2.62e-5)" "validated prognostic favorable (8.88e-5)" "unprognostic (1.18e-3)" "unprognostic (1.69e-3)" "unprognostic (2.14e-1)" "unprognostic (1.39e-1)" "unprognostic (5.27e-2)" "unprognostic (3.30e-1)" "unprognostic (6.49e-2)" "unprognostic (4.34e-2)" "unprognostic (6.74e-2)" "unprognostic (1.45e-1)" "unprognostic (9.51e-3)" "unprognostic (5.06e-3)" "unprognostic (2.21e-1)" "unprognostic (1.10e-1)" "unprognostic (9.42e-2)" "unprognostic (1.36e-1)" "unprognostic (2.47e-1)" CENPE "KIF10, PPP1R61" ENSG00000138778 "Centromere protein E" Q02224 4 103105349-103198445 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Developmental protein, Motor protein" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 9.4;lymphoid tissue: 8.6" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 79.6;Early primary spermatocytes: 95.1;Erythrocyte progenitors: 238.4;Extravillous trophoblasts: 62.8;Megakaryocyte progenitors: 159.6;Monocyte progenitors: 280.9;Neutrophil progenitors: 108.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "basophil: 2.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Pancreas - Macrophages, Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Not detected" "Not detected" "Not detected" "Not detected" "HPA011110, HPA042294" Enhanced Supported "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes Yes "Cluster 41: Basophils - Unknown function" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 45: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Non-specific - Cell proliferation" 23 Microtubules "Cytokinetic bridge, Mitotic spindle" "HPA011110: , HPA042294: " "unprognostic (4.19e-2)" "unprognostic (6.93e-2)" "unprognostic (3.89e-1)" "unprognostic (7.24e-2)" "unprognostic (1.16e-2)" "unprognostic (8.05e-2)" "unprognostic (4.53e-1)" "unprognostic (1.34e-1)" "unprognostic (6.73e-2)" "unprognostic (3.24e-3)" "potential prognostic unfavorable (4.10e-5)" "potential prognostic unfavorable (2.70e-5)" "unprognostic (1.33e-3)" "unprognostic (3.21e-1)" "unprognostic (2.42e-1)" "unprognostic (2.55e-1)" "unprognostic (4.41e-1)" "potential prognostic unfavorable (3.81e-5)" "unprognostic (1.67e-3)" "unprognostic (7.09e-2)" "unprognostic (1.95e-2)" "unprognostic (5.53e-3)" "unprognostic (1.97e-2)" "unprognostic (1.50e-1)" "unprognostic (1.56e-2)" CENPF hcp-1 ENSG00000117724 "Centromere protein F" P49454 1 214603185-214664574 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, DNA synthesis, Mitosis, Myogenesis" "Developmental protein" "Cancer-related genes, Ciliopathy, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 19.8;lymphoid tissue: 23.7;testis: 7.3" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 189.9;Enteric transient amplifying cells: 105.0;Erythrocyte progenitors: 597.7;Esophageal basal cells: 104.6;Late primary spermatocytes: 243.5;Megakaryocyte progenitors: 387.8;Monocyte progenitors: 507.8;Neutrophil progenitors: 166.0" "Cell type enhanced" "Detected in many" "ependymal cell: 9.8;leukocyte: 6.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" "HPA052382, HPA064308, CAB070134" Enhanced Supported Nucleoplasm Yes Yes 5000 "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 17: Choroid plexus - Cilium" "Cluster 45: Non-specific - Nuclear processes" "Cluster 27: Non-specific - Cell proliferation" 13 Nucleoplasm "CAB070134: , HPA052382: , HPA064308: " "unprognostic (1.86e-1)" "unprognostic (1.68e-1)" "unprognostic (1.46e-1)" "unprognostic (7.58e-2)" "unprognostic (5.23e-2)" "unprognostic (7.69e-2)" "unprognostic (1.46e-1)" "unprognostic (3.82e-2)" "unprognostic (5.29e-2)" "potential prognostic unfavorable (1.17e-5)" "validated prognostic unfavorable (5.29e-6)" "validated prognostic unfavorable (2.58e-7)" "potential prognostic unfavorable (3.29e-8)" "validated prognostic unfavorable (3.46e-5)" "validated prognostic unfavorable (1.26e-5)" "potential prognostic unfavorable (4.12e-5)" "unprognostic (6.11e-3)" "unprognostic (1.79e-2)" "unprognostic (4.77e-2)" "unprognostic (1.62e-1)" "unprognostic (5.51e-2)" "potential prognostic unfavorable (4.13e-4)" "unprognostic (2.16e-3)" "unprognostic (9.68e-3)" "unprognostic (6.37e-2)" "unprognostic (1.99e-2)" "unprognostic (6.04e-2)" "unprognostic (1.77e-2)" "unprognostic (6.12e-2)" "unprognostic (4.44e-2)" "unprognostic (8.05e-3)" CENPH ENSG00000153044 "Centromere protein H" Q9H3R5 5 69189574-69210357 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 31.8;testis: 27.8" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 222.3;Early primary spermatocytes: 307.5;Erythrocyte progenitors: 123.0;Extravillous trophoblasts: 61.1;Megakaryocyte progenitors: 60.5;Migrating cytotrophoblasts: 61.3;Oocytes: 290.1;Undifferentiated spermatogonia: 74.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA036494 Approved Supported "Nucleoplasm,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 43: Non-specific - Transcription & Translation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 11: White matter - Signal transduction" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 3: Early primary spermatocytes - Early meiosis" 50 "Nucleoplasm, Nucleoli rim" "Mitotic chromosome" "HPA036494: " "unprognostic (5.26e-2)" "unprognostic (8.26e-2)" "unprognostic (4.49e-3)" "unprognostic (1.09e-2)" "unprognostic (9.24e-2)" "unprognostic (4.35e-2)" "unprognostic (2.07e-1)" "unprognostic (2.85e-2)" "unprognostic (5.52e-2)" "potential prognostic unfavorable (6.68e-5)" "unprognostic (4.72e-3)" "unprognostic (3.64e-3)" "unprognostic (1.29e-3)" "validated prognostic unfavorable (4.44e-5)" "validated prognostic unfavorable (1.19e-5)" "potential prognostic unfavorable (7.26e-6)" "unprognostic (5.38e-3)" "unprognostic (4.86e-3)" "unprognostic (1.62e-1)" "unprognostic (6.95e-3)" "unprognostic (2.62e-2)" "unprognostic (2.04e-2)" "unprognostic (4.01e-3)" "unprognostic (8.53e-2)" "unprognostic (3.31e-2)" "unprognostic (4.03e-2)" "unprognostic (4.43e-2)" "unprognostic (2.19e-1)" "unprognostic (5.17e-1)" "unprognostic (1.64e-1)" "unprognostic (7.75e-3)" CENPI "CENP-I, FSHPRH1, LRPR1, Mis6" ENSG00000102384 "Centromere protein I" Q92674 X 101098188-101166126 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 5.2;lymphoid tissue: 4.9" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 47.8;Megakaryocyte progenitors: 31.9;Monocyte progenitors: 62.3;Neutrophil progenitors: 34.1;Respiratory deuterosomal cells: 27.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach)" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA068902, HPA071514" Supported "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 7: Non-specific - Innate immune response" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 6: Non-specific - Immune response" "Cluster 36: Non-specific - mRNA processing" "Cluster 27: Non-specific - Cell proliferation" 15 "Nuclear bodies" Nucleoplasm "HPA068902: , HPA071514: " "unprognostic (2.01e-2)" "unprognostic (4.54e-2)" "unprognostic (1.20e-1)" "unprognostic (1.84e-1)" "unprognostic (3.24e-2)" "unprognostic (1.76e-1)" "unprognostic (1.27e-1)" "unprognostic (9.36e-2)" "unprognostic (3.51e-2)" "unprognostic (1.44e-3)" "unprognostic (1.16e-3)" "potential prognostic unfavorable (1.95e-5)" "potential prognostic unfavorable (1.01e-4)" "validated prognostic unfavorable (8.43e-6)" "validated prognostic unfavorable (7.44e-6)" "unprognostic (4.43e-3)" "potential prognostic unfavorable (1.14e-4)" "unprognostic (1.07e-1)" "unprognostic (2.86e-1)" "unprognostic (1.06e-1)" "unprognostic (4.34e-1)" "unprognostic (1.20e-3)" "unprognostic (3.21e-3)" "unprognostic (9.52e-3)" "unprognostic (7.10e-3)" "unprognostic (1.22e-2)" "unprognostic (3.53e-2)" "unprognostic (2.79e-3)" "unprognostic (5.13e-2)" "unprognostic (2.19e-1)" CENPJ "BM032, CPAP, LAP, LIP1, MCPH6, Sas-4, SASS4, SCKL4" ENSG00000151849 "Centromere protein J" Q9HC77 13 24882279-24922889 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Dwarfism, Intellectual disability, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 15.7" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 80.1;Early spermatids: 230.2;Late primary spermatocytes: 59.7;Megakaryocyte progenitors: 134.0;Monocyte progenitors: 66.0;Oligodendrocytes: 62.8" "Cell type enriched" "Detected in all" 7 "committed oligodendrocyte precursor: 237.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076638 Supported Centrosome,Acrosome NA NA "Cluster 67: Testis - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 60 Centrosome Acrosome "HPA076638: " "unprognostic (1.73e-1)" "unprognostic (9.10e-2)" "unprognostic (7.08e-2)" "unprognostic (9.65e-2)" "unprognostic (1.26e-2)" "unprognostic (1.26e-1)" "unprognostic (1.59e-1)" "potential prognostic favorable (3.24e-4)" "unprognostic (3.90e-2)" "unprognostic (2.06e-2)" "unprognostic (1.23e-1)" "unprognostic (1.29e-2)" "potential prognostic unfavorable (9.24e-5)" "unprognostic (1.84e-2)" "unprognostic (8.08e-3)" "unprognostic (1.27e-1)" "unprognostic (3.24e-2)" "unprognostic (4.62e-2)" "unprognostic (4.77e-1)" "unprognostic (9.07e-2)" "unprognostic (2.65e-3)" "unprognostic (6.76e-2)" "unprognostic (2.70e-2)" "unprognostic (2.27e-1)" "unprognostic (8.23e-2)" "unprognostic (1.02e-1)" "unprognostic (5.75e-2)" "unprognostic (1.05e-1)" "unprognostic (1.62e-1)" CENPK "CENP-K, FKSG14, SOLT" ENSG00000123219 "Centromere protein K" Q9BS16 5 65517766-65563168 "Disease related genes, Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 23.5;lymphoid tissue: 20.7" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 110.5;Early primary spermatocytes: 165.0;Early spermatids: 67.2;Erythrocyte progenitors: 172.6;Extravillous trophoblasts: 65.7;Megakaryocyte progenitors: 163.0;Megakaryocyte-Erythroid progenitors: 81.4;Monocyte progenitors: 135.6;Neutrophil progenitors: 116.2;Oocytes: 82.9" "Cell type enhanced" "Detected in many" "leukocyte: 40.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA Yes "Cluster 5: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 6: Non-specific - Immune response" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Non-specific - Cell proliferation" 22 "unprognostic (6.11e-2)" "unprognostic (1.10e-1)" "unprognostic (9.71e-2)" "unprognostic (6.44e-2)" "unprognostic (1.74e-1)" "unprognostic (7.89e-2)" "unprognostic (1.60e-1)" "unprognostic (3.82e-2)" "unprognostic (8.15e-3)" "potential prognostic unfavorable (4.87e-4)" "potential prognostic unfavorable (2.27e-4)" "unprognostic (2.29e-2)" "unprognostic (7.27e-3)" "validated prognostic unfavorable (3.07e-4)" "validated prognostic unfavorable (1.32e-4)" "validated prognostic unfavorable (5.49e-5)" "validated prognostic unfavorable (1.14e-5)" "unprognostic (3.71e-2)" "unprognostic (2.84e-1)" "unprognostic (3.31e-1)" "unprognostic (1.87e-1)" "unprognostic (6.49e-3)" "potential prognostic unfavorable (1.67e-4)" "unprognostic (1.27e-1)" "unprognostic (1.81e-2)" "unprognostic (1.51e-1)" "unprognostic (5.44e-2)" "unprognostic (9.24e-2)" "unprognostic (2.36e-1)" "unprognostic (3.55e-2)" "unprognostic (8.86e-2)" CENPL "C1orf155, dJ383J4.3, FLJ31044" ENSG00000120334 "Centromere protein L" Q8N0S6 1 173799550-173824883 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 8.9;testis: 9.1" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 45.8;Erythrocyte progenitors: 30.9;Monocyte progenitors: 33.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044520 Uncertain NA Yes "Cluster 5: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 55: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 27: Non-specific - Cell proliferation" 4 "HPA044520: " "unprognostic (9.42e-3)" "unprognostic (3.24e-3)" "unprognostic (6.82e-2)" "unprognostic (2.31e-1)" "unprognostic (2.67e-1)" "unprognostic (1.79e-1)" "unprognostic (1.65e-1)" "unprognostic (1.77e-1)" "unprognostic (1.14e-2)" "unprognostic (2.04e-1)" "unprognostic (1.77e-3)" "unprognostic (1.07e-3)" "unprognostic (2.32e-2)" "validated prognostic unfavorable (2.55e-5)" "validated prognostic unfavorable (4.95e-6)" "unprognostic (4.59e-3)" "unprognostic (9.31e-3)" "unprognostic (1.13e-1)" "unprognostic (5.08e-1)" "unprognostic (9.45e-2)" "unprognostic (2.36e-1)" "unprognostic (1.07e-2)" "unprognostic (3.58e-3)" "unprognostic (8.77e-2)" "unprognostic (2.41e-1)" "unprognostic (1.99e-1)" "unprognostic (8.86e-3)" "unprognostic (6.04e-2)" "unprognostic (3.21e-2)" "unprognostic (2.35e-2)" "unprognostic (2.73e-1)" CENPM "C22orf18, CENP-M, MGC861, Pane1" ENSG00000100162 "Centromere protein M" Q9NSP4 22 41938737-41947152 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 27.4;lymphoid tissue: 23.4" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 118.5;Enteric transient amplifying cells: 86.6;Epididymal efferent duct ciliated cells: 157.4;Erythrocyte progenitors: 84.8;Esophageal basal cells: 72.7;Fallopian tube ciliated cells: 115.3;Hofbauer cells: 72.5;Megakaryocyte progenitors: 56.8;Migrating cytotrophoblasts: 56.2;Monocyte progenitors: 60.9;Respiratory ciliated cells: 87.3" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "T-reg: 51.0" "Group enriched" "Detected in many" 6 "B-cells: 38.8;T-cells: 51.0" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042404 Enhanced NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 15: Non-specific - Transcription" "Cluster 35: RS4;11 - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 15 "HPA042404: " "unprognostic (5.20e-2)" "unprognostic (1.72e-2)" "unprognostic (2.03e-1)" "potential prognostic favorable (9.68e-6)" "unprognostic (7.55e-2)" "unprognostic (3.51e-2)" "unprognostic (2.23e-2)" "potential prognostic favorable (8.03e-4)" "unprognostic (3.91e-1)" "potential prognostic unfavorable (9.18e-4)" "validated prognostic unfavorable (2.08e-7)" "validated prognostic unfavorable (6.97e-4)" "potential prognostic unfavorable (8.56e-7)" "validated prognostic unfavorable (3.48e-6)" "validated prognostic unfavorable (6.01e-8)" "potential prognostic unfavorable (2.00e-5)" "unprognostic (2.38e-3)" "unprognostic (2.41e-2)" "unprognostic (1.61e-1)" "unprognostic (1.60e-1)" "unprognostic (2.67e-2)" "unprognostic (2.09e-2)" "unprognostic (1.00e-1)" "unprognostic (1.37e-1)" "unprognostic (1.12e-1)" "unprognostic (1.11e-2)" "unprognostic (4.15e-1)" "unprognostic (7.12e-3)" "unprognostic (3.61e-1)" "unprognostic (9.29e-2)" "unprognostic (1.21e-2)" CENPN "BM039, C16orf60, FLJ13607, FLJ22660" ENSG00000166451 "Centromere protein N" Q96H22 16 81006552-81033114 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 35.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 58.6;Cytotrophoblasts: 57.4;Early primary spermatocytes: 66.5;Enteric transient amplifying cells: 57.3;Esophageal basal cells: 78.6;Extravillous trophoblasts: 111.0;Gastric progenitor cells: 91.0;Late primary spermatocytes: 55.0;Migrating cytotrophoblasts: 90.2;Prostatic glandular cells: 78.2" "Cell type enhanced" "Detected in many" "oligodendrocyte: 9.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Prostate glandular cells, Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA052870 Supported Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 11: White matter - Signal transduction" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 27: Non-specific - Cell proliferation" 9 Nucleoplasm "HPA052870: " "unprognostic (3.91e-3)" "unprognostic (7.49e-3)" "unprognostic (1.62e-1)" "unprognostic (1.28e-1)" "unprognostic (1.20e-1)" "unprognostic (6.11e-2)" "unprognostic (3.73e-2)" "unprognostic (3.82e-2)" "unprognostic (8.27e-3)" "unprognostic (2.06e-2)" "unprognostic (1.16e-3)" "unprognostic (3.74e-2)" "potential prognostic unfavorable (8.40e-11)" "validated prognostic unfavorable (6.23e-4)" "validated prognostic unfavorable (6.07e-4)" "potential prognostic unfavorable (6.54e-4)" "unprognostic (1.79e-3)" "unprognostic (1.16e-1)" "unprognostic (1.23e-2)" "unprognostic (1.39e-2)" "unprognostic (4.77e-1)" "potential prognostic unfavorable (1.38e-4)" "unprognostic (1.62e-2)" "unprognostic (8.66e-2)" "unprognostic (1.46e-2)" "unprognostic (2.15e-1)" "unprognostic (6.08e-2)" "unprognostic (9.54e-2)" "unprognostic (6.69e-2)" "unprognostic (5.43e-2)" "unprognostic (5.11e-2)" CENPO "CENP-O, MGC11266" ENSG00000138092 "Centromere protein O" Q9BU64 2 24793136-24822376 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 30.3;Epicardial cells: 38.7;Erythrocyte progenitors: 37.5;Extravillous trophoblasts: 28.8;Monocyte progenitors: 30.9;Pericytes: 34.3;Vascular smooth muscle cells: 27.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA046189 Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 27: Breast cancer - Unknown function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 17 Nucleoplasm "Nuclear bodies" "HPA046189: " "unprognostic (9.26e-2)" "unprognostic (5.22e-3)" "unprognostic (1.32e-1)" "unprognostic (7.71e-2)" "unprognostic (2.56e-1)" "unprognostic (4.54e-1)" "unprognostic (4.73e-1)" "unprognostic (8.26e-2)" "unprognostic (9.26e-2)" "potential prognostic unfavorable (4.52e-4)" "validated prognostic unfavorable (1.68e-5)" "validated prognostic unfavorable (4.08e-4)" "unprognostic (1.70e-1)" "potential prognostic unfavorable (2.25e-6)" "unprognostic (1.70e-3)" "potential prognostic unfavorable (9.62e-4)" "unprognostic (2.76e-2)" "unprognostic (1.78e-3)" "unprognostic (2.48e-3)" "unprognostic (2.03e-1)" "unprognostic (1.20e-1)" "unprognostic (5.07e-2)" "potential prognostic unfavorable (5.64e-4)" "unprognostic (3.37e-2)" "unprognostic (1.03e-3)" "unprognostic (2.25e-1)" "unprognostic (3.83e-2)" "unprognostic (8.57e-2)" "unprognostic (2.20e-1)" "unprognostic (3.15e-1)" "unprognostic (3.82e-1)" CENPP "CENP-P, RP11-19J3.3" ENSG00000188312 "Centromere protein P" Q6IPU0 9 92325953-92620529 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 20.3" "Cell type enhanced" "Detected in all" "Early primary spermatocytes: 400.2;Erythrocyte progenitors: 622.7;Monocyte progenitors: 527.2;Neutrophil progenitors: 404.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021787, HPA058945" Uncertain Supported Nucleoplasm,Nucleoli NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 37: Skin - Keratinization" "Cluster 35: Non-specific - DNA binding" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 31 Nucleoplasm Nucleoli "HPA021787: , HPA058945: " "unprognostic (1.10e-3)" "unprognostic (6.50e-2)" "unprognostic (2.78e-1)" "potential prognostic favorable (3.05e-5)" "unprognostic (3.41e-1)" "unprognostic (1.11e-1)" "potential prognostic unfavorable (8.79e-4)" "unprognostic (5.80e-3)" "potential prognostic favorable (1.19e-4)" "unprognostic (5.17e-3)" "unprognostic (1.12e-1)" "unprognostic (2.66e-3)" "unprognostic (4.74e-2)" "potential prognostic unfavorable (4.27e-5)" "unprognostic (3.29e-1)" "unprognostic (1.16e-2)" "unprognostic (2.89e-3)" "unprognostic (3.99e-2)" "unprognostic (3.73e-1)" "unprognostic (5.06e-2)" "unprognostic (2.17e-2)" "unprognostic (5.05e-2)" "unprognostic (2.69e-1)" "unprognostic (1.40e-1)" "unprognostic (1.61e-2)" "unprognostic (3.09e-3)" "potential prognostic unfavorable (6.70e-4)" "unprognostic (1.74e-1)" "unprognostic (8.23e-2)" "unprognostic (8.09e-2)" "unprognostic (1.67e-1)" CENPQ "C6orf139, CENP-Q, FLJ10545" ENSG00000031691 "Centromere protein Q" Q7L2Z9 6 49463370-49493107 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 58.1;Extravillous trophoblasts: 44.8;Oocytes: 55.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029043, HPA046634, HPA054965" Approved Supported Nucleoplasm NA Yes "Cluster 5: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 27: Non-specific - Cell proliferation" 34 Nucleoplasm "HPA029043: , HPA046634: , HPA054965: " "unprognostic (1.02e-1)" "unprognostic (7.96e-2)" "potential prognostic unfavorable (2.60e-4)" "unprognostic (1.16e-3)" "unprognostic (2.70e-1)" "unprognostic (1.76e-1)" "unprognostic (4.37e-2)" "unprognostic (1.76e-1)" "unprognostic (1.70e-1)" "unprognostic (3.09e-3)" "potential prognostic favorable (4.14e-5)" "unprognostic (9.88e-2)" "unprognostic (1.20e-1)" "validated prognostic unfavorable (1.21e-5)" "validated prognostic unfavorable (6.25e-5)" "unprognostic (2.54e-2)" "unprognostic (1.80e-2)" "unprognostic (4.37e-3)" "unprognostic (1.34e-1)" "unprognostic (5.95e-3)" "unprognostic (2.87e-2)" "unprognostic (1.54e-1)" "unprognostic (2.93e-2)" "unprognostic (6.20e-2)" "unprognostic (1.50e-2)" "unprognostic (1.35e-2)" "unprognostic (1.96e-2)" "unprognostic (9.53e-2)" "unprognostic (9.43e-2)" "unprognostic (2.56e-1)" "unprognostic (1.93e-2)" CENPS "APITD1, CENP-S, FAAP16, MHF1" ENSG00000175279 "Centromere protein S" Q8N2Z9 1 10430433-10442808 "Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Mitosis" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 46.4" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 8.1;Choroid plexus epithelial cells: 9.9;Early primary spermatocytes: 13.0;Early spermatids: 11.3;Ependymal cells: 15.3;Epididymal efferent duct ciliated cells: 9.7;Late primary spermatocytes: 29.6;Late spermatids: 24.6;Other brain neurons: 8.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 72: Kidney - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 34: Ciliated cells - Cilia assembly & function" 29 "unprognostic (5.56e-2)" "unprognostic (1.40e-1)" "potential prognostic favorable (3.94e-4)" "unprognostic (3.07e-3)" "unprognostic (3.07e-2)" "unprognostic (1.52e-1)" "unprognostic (6.82e-2)" "unprognostic (1.42e-1)" "unprognostic (3.18e-2)" "potential prognostic favorable (8.62e-7)" "unprognostic (3.99e-2)" "potential prognostic favorable (4.89e-4)" "potential prognostic unfavorable (9.62e-4)" "unprognostic (3.73e-1)" "unprognostic (2.56e-1)" "unprognostic (1.57e-1)" "unprognostic (1.19e-1)" "unprognostic (1.31e-1)" "unprognostic (4.76e-1)" "unprognostic (1.02e-1)" "unprognostic (1.15e-1)" "unprognostic (1.53e-1)" "unprognostic (1.94e-1)" "unprognostic (2.20e-1)" "potential prognostic unfavorable (8.41e-4)" "unprognostic (2.28e-1)" "unprognostic (8.43e-2)" "unprognostic (1.95e-1)" "unprognostic (1.62e-1)" CENPS-CORT APITD1-CORT ENSG00000251503 "CENPS-CORT readthrough" 1 10430102-10452153 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 4 "testis: 33.3" "Group enriched" "Detected in many" 4 "Early spermatids: 54.8;Late primary spermatocytes: 67.4;Late spermatids: 162.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 67: Testis - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 37: Non-specific - mRNA processing" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" "unprognostic (2.49e-1)" "unprognostic (3.84e-1)" "unprognostic (7.24e-2)" "unprognostic (8.87e-2)" "unprognostic (1.50e-1)" "unprognostic (2.63e-1)" "unprognostic (1.78e-1)" "unprognostic (2.32e-3)" "unprognostic (2.76e-1)" "unprognostic (2.09e-1)" "unprognostic (2.09e-3)" "unprognostic (1.51e-2)" "unprognostic (1.28e-1)" "unprognostic (2.46e-1)" "unprognostic (2.47e-1)" "unprognostic (7.58e-3)" "unprognostic (6.34e-2)" "unprognostic (1.78e-3)" "unprognostic (1.34e-1)" "unprognostic (2.49e-1)" "unprognostic (9.26e-2)" "unprognostic (2.36e-3)" "unprognostic (8.25e-2)" "unprognostic (8.10e-2)" "unprognostic (2.35e-1)" "unprognostic (3.86e-2)" "unprognostic (1.77e-1)" CENPT "C16orf56, CENP-T, FLJ13111" ENSG00000102901 "Centromere protein T" Q96BT3 16 67828157-67847811 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" DNA-binding Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 97.3;Platelets: 142.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041220, HPA058036" Approved Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 47: Testis - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 47: Platelets - Hemostasis" 10 "Nuclear bodies" Nucleoplasm "HPA041220: , HPA058036: " "potential prognostic unfavorable (3.63e-4)" "unprognostic (1.24e-2)" "unprognostic (9.71e-2)" "unprognostic (8.60e-2)" "unprognostic (1.12e-1)" "unprognostic (8.57e-2)" "unprognostic (8.57e-2)" "potential prognostic favorable (2.54e-4)" "unprognostic (1.44e-2)" "unprognostic (1.25e-3)" "potential prognostic favorable (1.48e-5)" "unprognostic (1.91e-1)" "unprognostic (2.07e-1)" "unprognostic (2.76e-2)" "unprognostic (2.01e-1)" "unprognostic (2.13e-3)" "unprognostic (3.54e-2)" "unprognostic (1.40e-1)" "unprognostic (5.94e-1)" "unprognostic (8.33e-2)" "unprognostic (1.05e-2)" "unprognostic (5.11e-3)" "unprognostic (2.55e-3)" "unprognostic (1.32e-1)" "unprognostic (1.37e-1)" "unprognostic (4.25e-3)" "unprognostic (1.37e-1)" "unprognostic (2.48e-1)" "unprognostic (4.21e-1)" "unprognostic (6.56e-2)" "unprognostic (6.77e-2)" CENPU "CENP-50, CENP-U, KLIP1, MLF1IP, PBIP1" ENSG00000151725 "Centromere protein U" Q71F23 4 184694085-184734130 "Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 59.0;testis: 27.6" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 173.2;Early primary spermatocytes: 469.1;Early spermatids: 417.1;Erythrocyte progenitors: 230.2;Late primary spermatocytes: 809.4;Late spermatids: 1614.1;Neutrophils: 188.5;Oocytes: 239.5" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 6.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "basophil: 20.7;eosinophil: 14.3" "Lineage enriched" "Detected in all" 6 "granulocytes: 20.7" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Lung - Mitotic cells (Lung), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA022048 Supported "Nucleoplasm,Centriolar satellite" NA Yes "Cluster 42: Non-specific - Vesicular transport" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 25: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 27 "Nucleoplasm, Centriolar satellite" "HPA022048: " "unprognostic (1.09e-1)" "unprognostic (1.57e-1)" "potential prognostic favorable (7.51e-4)" "unprognostic (3.68e-2)" "unprognostic (2.58e-1)" "unprognostic (3.63e-2)" "unprognostic (3.77e-2)" "unprognostic (1.34e-1)" "unprognostic (1.08e-1)" "unprognostic (3.31e-3)" "unprognostic (1.57e-2)" "potential prognostic unfavorable (4.25e-4)" "unprognostic (3.87e-3)" "potential prognostic unfavorable (1.35e-5)" "unprognostic (5.98e-3)" "unprognostic (2.04e-2)" "unprognostic (1.85e-1)" "unprognostic (1.63e-1)" "unprognostic (1.33e-1)" "unprognostic (1.70e-3)" "unprognostic (2.71e-3)" "unprognostic (2.12e-2)" "unprognostic (2.49e-1)" "unprognostic (2.04e-1)" "unprognostic (1.59e-3)" "unprognostic (1.29e-2)" "unprognostic (1.15e-1)" "unprognostic (1.86e-2)" "unprognostic (2.37e-1)" CENPV "CENP-V, p30, PRR6" ENSG00000166582 "Centromere protein V" Q7Z7K6 17 16342534-16353656 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 123.5;Early primary spermatocytes: 130.1;Enteric stem cells: 96.2;Enteric transient amplifying cells: 98.9;Enterocytes: 93.1;Gastric progenitor cells: 133.3;Megakaryocytes: 86.5;Paneth cells: 92.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 1.3;memory B-cell: 1.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen), Testis - Sertoli cells" "Low region specificity" "Detected in all" "HPA042529, HPA042616" Enhanced Supported "Nucleoplasm,Nuclear membrane,Nucleoli,Cytokinetic bridge,Midbody,Cytosol" Yes No "Cluster 22: Eosinophils - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 25 Nucleoplasm "Nuclear membrane, Nucleoli, Cytokinetic bridge, Midbody, Cytosol" "HPA042529: , HPA042616: " "unprognostic (2.63e-2)" "unprognostic (8.90e-2)" "unprognostic (4.12e-1)" "unprognostic (1.34e-2)" "unprognostic (5.58e-2)" "unprognostic (1.53e-1)" "unprognostic (4.51e-2)" "unprognostic (4.71e-2)" "unprognostic (1.64e-1)" "potential prognostic favorable (2.13e-7)" "unprognostic (1.05e-2)" "unprognostic (1.34e-1)" "unprognostic (2.21e-1)" "unprognostic (4.88e-2)" "unprognostic (4.47e-2)" "unprognostic (1.19e-2)" "unprognostic (1.06e-1)" "unprognostic (1.74e-3)" "unprognostic (7.18e-2)" "unprognostic (1.15e-1)" "unprognostic (4.17e-2)" "unprognostic (2.76e-1)" "unprognostic (1.57e-1)" "unprognostic (7.00e-3)" "unprognostic (4.08e-1)" "unprognostic (4.84e-2)" "unprognostic (1.67e-1)" "unprognostic (1.09e-1)" "unprognostic (6.03e-3)" "unprognostic (2.00e-1)" CENPVL1 "CENPVP1, PRR6L1" ENSG00000223591 "Centromere protein V like 1" A0A0U1RR11 X 51710512-51712131 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 5 "brain: 3.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 12: Bone cancer - Neuronal signaling" CENPVL2 CENPVP2 ENSG00000283093 "Centromere protein V like 2" P0DPI3 X 51681212-51682831 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 9 "brain: 4.0" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 12: Bone cancer - Neuronal signaling" CENPVL3 CENPVP3 ENSG00000224109 "Centromere protein V like 3" A0A0U1RRI6 X 51617020-51618912 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 5.0;testis: 3.5" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 1.5;Brain inhibitory neurons: 2.3;Granulosa cells: 1.6;Hematopoietic stem cells: 1.5;Late primary spermatocytes: 1.1;Late spermatids: 1.6;Megakaryocyte-Erythroid progenitors: 2.6;Migrating cytotrophoblasts: 1.1;Oligodendrocyte progenitor cells: 1.6;Other brain neurons: 7.6;Sertoli cells: 9.5;Undifferentiated spermatogonia: 1.9" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in single" "Prostate Adenocarcinoma (TCGA): 1.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Bone cancer: 8.9" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Testis - Sertoli cells" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 98: Neurons - Neurotransmission & signaling" "unprognostic (2.00e-1)" CENPW "C6orf173, CUG2" ENSG00000203760 "Centromere protein W" Q5EE01 6 126340115-126348875 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 47.7" "Cell type enhanced" "Detected in many" "Early spermatids: 242.6;Endometrial secretory cells: 106.0;Enteric transient amplifying cells: 119.5;Esophageal basal cells: 259.1;Extravillous trophoblasts: 183.2;Gastric progenitor cells: 276.8;Late primary spermatocytes: 499.4;Megakaryocytes: 111.3;Oocytes: 119.7;Submucosal glandular cells: 122.0" "Cell type enhanced" "Detected in many" "hippocampal dentate gyrus: 17.0" "Cancer enhanced" "Detected in all" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 175.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA067285 Supported Nucleoplasm NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 29: Forebrain - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 27: Non-specific - Cell proliferation" 6 Nucleoplasm "HPA067285: " "unprognostic (1.28e-2)" "potential prognostic unfavorable (1.26e-4)" "unprognostic (5.58e-2)" "potential prognostic favorable (7.79e-4)" "unprognostic (1.91e-1)" "unprognostic (2.07e-1)" "unprognostic (2.08e-1)" "unprognostic (2.54e-3)" "unprognostic (5.98e-2)" "potential prognostic unfavorable (5.01e-8)" "validated prognostic unfavorable (7.49e-10)" "validated prognostic unfavorable (2.84e-4)" "potential prognostic unfavorable (1.01e-8)" "validated prognostic unfavorable (7.27e-7)" "validated prognostic unfavorable (5.32e-8)" "potential prognostic unfavorable (8.01e-4)" "unprognostic (1.64e-3)" "unprognostic (2.45e-2)" "unprognostic (1.99e-1)" "unprognostic (2.04e-1)" "unprognostic (3.30e-2)" "unprognostic (4.83e-3)" "unprognostic (1.40e-2)" "unprognostic (1.60e-1)" "unprognostic (1.20e-1)" "unprognostic (3.19e-2)" "unprognostic (1.70e-1)" "unprognostic (4.98e-2)" "unprognostic (9.32e-2)" "unprognostic (1.62e-2)" "unprognostic (6.52e-2)" CENPX "CENP-X, FAAP10, MGC14480, MHF2, STRA13" ENSG00000169689 "Centromere protein X" A8MT69 17 82018702-82024107 "Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Mitosis" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 283.8;Enteric transient amplifying cells: 283.1;Esophageal basal cells: 428.8;Esophageal suprabasal cells: 275.9;Extravillous trophoblasts: 638.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Prostate - Prostate glandular cells, Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 64: Non-specific - Transcription" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 21 "unprognostic (1.36e-1)" "unprognostic (1.80e-1)" "unprognostic (8.91e-2)" "unprognostic (2.30e-2)" "unprognostic (1.80e-2)" "unprognostic (1.09e-1)" "unprognostic (1.16e-2)" "unprognostic (2.22e-1)" "unprognostic (4.16e-3)" "unprognostic (1.79e-1)" "unprognostic (1.09e-1)" "unprognostic (1.15e-1)" "unprognostic (3.19e-3)" "unprognostic (1.55e-2)" "unprognostic (3.07e-1)" "unprognostic (1.65e-1)" "unprognostic (4.55e-2)" "unprognostic (2.68e-3)" "unprognostic (1.19e-3)" "unprognostic (9.72e-2)" "unprognostic (1.47e-1)" "unprognostic (6.76e-2)" "unprognostic (1.34e-1)" "unprognostic (8.02e-2)" "unprognostic (7.99e-2)" "unprognostic (7.62e-2)" "unprognostic (4.99e-1)" "unprognostic (2.93e-1)" "unprognostic (4.44e-2)" CEP104 "CFAP256, GlyBP, JBTS25, KIAA0562, ROC22, RP1-286D6.4" ENSG00000116198 "Centrosomal protein 104" O60308 1 3812086-3857396 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Ciliopathy, Disease variant, Intellectual disability, Joubert syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 552.7;Late spermatids: 153.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010126 Approved NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 37: Non-specific - mRNA processing" "Cluster 79: Photoreceptor cells - Phototransduction" 1 "HPA010126: " "unprognostic (1.36e-1)" "unprognostic (3.68e-2)" "unprognostic (2.08e-2)" "unprognostic (5.16e-3)" "unprognostic (1.85e-2)" "unprognostic (1.15e-1)" "unprognostic (1.09e-1)" "unprognostic (4.57e-1)" "unprognostic (7.10e-2)" "validated prognostic favorable (1.91e-6)" "validated prognostic favorable (7.86e-4)" "unprognostic (1.59e-2)" "potential prognostic unfavorable (6.34e-4)" "unprognostic (1.75e-3)" "unprognostic (1.19e-1)" "unprognostic (3.44e-2)" "unprognostic (3.98e-2)" "unprognostic (3.58e-1)" "unprognostic (1.88e-1)" "unprognostic (3.51e-1)" "unprognostic (1.31e-1)" "unprognostic (9.55e-2)" "unprognostic (9.69e-2)" "unprognostic (1.98e-1)" "unprognostic (1.86e-3)" "unprognostic (1.88e-1)" "unprognostic (4.00e-2)" "unprognostic (2.23e-1)" "unprognostic (1.07e-1)" "unprognostic (3.20e-1)" CEP112 "CCDC46, MGC33887" ENSG00000154240 "Centrosomal protein 112" Q8N8E3 17 65635537-66192133 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 43.8" "Cell type enhanced" "Detected in many" "Early spermatids: 1527.4;Ependymal cells: 518.4;Lactotrophs: 504.6;Late spermatids: 2282.5;Rod photoreceptor cells: 1137.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 22.7" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Minor Salivary Gland - Endothelial cells, Prostate - Fibroblasts, Skin - Endothelial cells, Spleen - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069724 Approved "Nucleoplasm,Midbody ring,Centrosome,Cytosol" Yes NA "Cluster 22: Eosinophils - Transcription" "Cluster 47: Testis - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 5: Rhabdoid - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" 15 "Nucleoplasm, Centrosome" "Midbody ring, Cytosol" "HPA069724: " "unprognostic (1.63e-1)" "unprognostic (3.07e-1)" "unprognostic (8.75e-2)" "unprognostic (4.25e-1)" "unprognostic (6.19e-2)" "unprognostic (7.05e-3)" "potential prognostic unfavorable (7.65e-6)" "unprognostic (4.53e-2)" "unprognostic (4.17e-3)" "unprognostic (7.31e-3)" "unprognostic (2.01e-3)" "unprognostic (7.57e-2)" "unprognostic (6.38e-2)" "unprognostic (5.44e-2)" "unprognostic (4.53e-2)" "unprognostic (9.80e-3)" "unprognostic (1.14e-3)" "unprognostic (2.33e-2)" "unprognostic (1.49e-1)" "unprognostic (1.88e-1)" "unprognostic (1.39e-2)" "unprognostic (5.49e-3)" "unprognostic (3.89e-2)" "unprognostic (3.56e-1)" "unprognostic (3.21e-3)" "unprognostic (4.56e-2)" "unprognostic (2.69e-2)" "unprognostic (2.87e-1)" "unprognostic (1.83e-2)" "unprognostic (4.87e-2)" CEP120 "CCDC100, FLJ36090" ENSG00000168944 "Centrosomal protein 120" Q8N960 5 123344890-123423592 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant, Joubert syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 138.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028823, HPA051556" Uncertain Uncertain "Microtubules,Mitotic spindle,Cytosol,Perinuclear theca,Flagellar centriole,Mid piece,Annulus" Yes NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 61: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 9: T-cells - Adaptive immunity: Regulation" 12 "Microtubules, Flagellar centriole, Annulus" "Mitotic spindle, Cytosol, Perinuclear theca, Mid piece" "HPA028823: , HPA051556: " "unprognostic (1.36e-1)" "unprognostic (1.28e-1)" "unprognostic (3.92e-1)" "unprognostic (1.33e-1)" "unprognostic (8.95e-2)" "unprognostic (2.06e-1)" "unprognostic (1.51e-1)" "unprognostic (1.17e-1)" "unprognostic (7.48e-2)" "potential prognostic unfavorable (2.63e-4)" "validated prognostic favorable (1.09e-10)" "validated prognostic favorable (5.98e-5)" "unprognostic (4.27e-2)" "unprognostic (2.67e-1)" "unprognostic (1.52e-3)" "unprognostic (4.48e-2)" "unprognostic (2.87e-1)" "unprognostic (7.73e-2)" "unprognostic (1.29e-1)" "unprognostic (3.30e-2)" "unprognostic (6.69e-3)" "unprognostic (3.26e-1)" "unprognostic (2.42e-1)" "unprognostic (1.13e-1)" "unprognostic (5.35e-2)" "unprognostic (1.37e-1)" "unprognostic (1.84e-1)" "unprognostic (1.71e-1)" "unprognostic (1.85e-1)" "unprognostic (4.18e-2)" "unprognostic (1.31e-1)" CEP126 KIAA1377 ENSG00000110318 "Centrosomal protein 126" Q9P2H0 11 101915010-102001062 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 39.4" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 397.0;Endometrial ciliated cells: 324.1;Ependymal cells: 836.5;Epididymal efferent duct ciliated cells: 385.7;Fallopian tube ciliated cells: 602.7;Lactotrophs: 308.8;Respiratory ciliated cells: 802.5;Somatotrophs: 690.5;Thyrotrophs: 684.9" "Cell type enhanced" "Detected in all" "ependymal cell: 902.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Prostate - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 11: Neuronal - Sensory perception" "Cluster 34: Ciliated cells - Cilia assembly & function" 17 "unprognostic (3.88e-1)" "unprognostic (5.51e-2)" "unprognostic (3.16e-1)" "unprognostic (1.81e-1)" "unprognostic (2.68e-1)" "unprognostic (3.84e-2)" "unprognostic (3.33e-1)" "unprognostic (3.44e-2)" "potential prognostic unfavorable (3.39e-4)" "unprognostic (6.68e-3)" "unprognostic (2.79e-1)" "unprognostic (2.51e-3)" "unprognostic (4.86e-2)" "unprognostic (2.49e-2)" "unprognostic (1.18e-2)" "unprognostic (1.39e-1)" "unprognostic (5.77e-2)" "unprognostic (4.61e-3)" "unprognostic (2.15e-3)" "unprognostic (1.18e-1)" "unprognostic (1.55e-1)" "unprognostic (1.55e-1)" "unprognostic (3.88e-2)" "unprognostic (1.35e-1)" "unprognostic (2.34e-1)" "unprognostic (6.47e-2)" CEP128 "C14orf145, C14orf61" ENSG00000100629 "Centrosomal protein 128" Q6ZU80 14 80476983-80959517 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 23.1" "Cell type enhanced" "Detected in many" "Ependymal cells: 208.7;Monocyte progenitors: 314.1;Myonuclei: 419.8;Neutrophil progenitors: 245.1;Plasma cells: 461.2;Respiratory ciliated cells: 222.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 7.9" "Group enriched" "Detected in many" 4 "dendritic cells: 6.9;T-cells: 7.9" "Cancer enhanced" "Detected in all" "Myeloma: 52.0" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001116, HPA005846, HPA018498" Uncertain Supported Centrosome NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 80: Thymus - Adaptive immune response" "Cluster 54: Immune cells - T cell receptor" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 44: Plasma cells - Antibody production & secretion" 14 Centrosome "HPA001116: , HPA005846: , HPA018498: " "unprognostic (1.57e-1)" "unprognostic (1.50e-1)" "unprognostic (3.86e-2)" "unprognostic (6.47e-2)" "unprognostic (2.13e-2)" "unprognostic (1.94e-1)" "unprognostic (9.90e-2)" "unprognostic (2.46e-2)" "unprognostic (1.10e-1)" "unprognostic (3.46e-1)" "unprognostic (3.84e-1)" "unprognostic (5.34e-2)" "unprognostic (8.84e-2)" "unprognostic (5.58e-2)" "unprognostic (3.07e-1)" "unprognostic (1.14e-1)" "unprognostic (7.69e-2)" "unprognostic (1.25e-1)" "potential prognostic unfavorable (8.89e-4)" "unprognostic (2.92e-2)" "unprognostic (6.27e-2)" "potential prognostic favorable (7.74e-4)" "unprognostic (1.92e-1)" "unprognostic (7.14e-2)" "unprognostic (6.14e-2)" "unprognostic (2.36e-1)" "unprognostic (4.83e-2)" CEP131 "AZ1, AZI1, KIAA1118" ENSG00000141577 "Centrosomal protein 131" Q9UPN4 17 81189593-81222999 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cilium biogenesis/degradation, Differentiation, Spermatogenesis, Transport" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 26.0;Late spermatids: 28.7;Undifferentiated spermatogonia: 34.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024019 Approved Supported "Microtubules,Cytokinetic bridge,Primary cilium,Centriolar satellite,Basal body,Flagellar centriole" Yes No "Cluster 32: Basophils - Transcription" "Cluster 67: Testis - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 46 "Centriolar satellite, Basal body, Flagellar centriole" "Microtubules, Cytokinetic bridge, Primary cilium" "HPA024019: " "unprognostic (1.99e-1)" "unprognostic (2.27e-2)" "unprognostic (2.12e-1)" "unprognostic (5.33e-2)" "unprognostic (1.12e-1)" "unprognostic (3.39e-1)" "unprognostic (3.58e-2)" "unprognostic (8.83e-2)" "potential prognostic unfavorable (8.99e-4)" "potential prognostic unfavorable (2.58e-4)" "unprognostic (3.86e-2)" "unprognostic (5.96e-2)" "potential prognostic unfavorable (1.02e-5)" "unprognostic (2.51e-1)" "unprognostic (2.58e-2)" "unprognostic (2.02e-1)" "unprognostic (2.45e-2)" "unprognostic (1.02e-1)" "potential prognostic favorable (3.71e-5)" "unprognostic (3.08e-3)" "potential prognostic unfavorable (4.96e-4)" "unprognostic (1.68e-2)" "unprognostic (2.23e-1)" "unprognostic (5.10e-3)" "unprognostic (7.60e-2)" "unprognostic (2.80e-2)" "unprognostic (7.98e-2)" "unprognostic (2.20e-1)" "unprognostic (2.14e-1)" CEP135 "CEP4, FLJ13621, KIAA0635" ENSG00000174799 "Centrosomal protein 135" Q66GS9 4 55948871-56033361 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Intellectual disability, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 129.2;Late primary spermatocytes: 105.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041539 Approved "Acrosome,Mid piece,Principal piece,Annulus" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 116 "Mid piece, Principal piece" "Acrosome, Annulus" "HPA041539: " "unprognostic (2.70e-2)" "unprognostic (3.99e-2)" "unprognostic (7.31e-2)" "unprognostic (1.55e-2)" "unprognostic (9.31e-2)" "unprognostic (5.68e-2)" "unprognostic (3.71e-1)" "unprognostic (4.64e-1)" "unprognostic (2.98e-2)" "unprognostic (2.62e-3)" "unprognostic (8.97e-3)" "unprognostic (9.38e-2)" "unprognostic (9.70e-3)" "potential prognostic unfavorable (1.07e-4)" "unprognostic (4.29e-3)" "unprognostic (9.03e-2)" "unprognostic (1.72e-1)" "unprognostic (1.17e-1)" "unprognostic (7.97e-2)" "unprognostic (1.95e-1)" "unprognostic (4.53e-3)" "unprognostic (1.40e-1)" "unprognostic (2.64e-2)" "unprognostic (3.40e-2)" "unprognostic (8.78e-3)" "unprognostic (9.39e-2)" "unprognostic (1.64e-1)" "unprognostic (1.59e-2)" "unprognostic (1.19e-1)" CEP152 "KIAA0912, MCPH9, SCKL5" ENSG00000103995 "Centrosomal protein 152" O94986 15 48712928-48811146 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Disease variant, Dwarfism, Intellectual disability, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 15.5" "Cell type enhanced" "Detected in many" "Early spermatids: 311.5;Erythrocyte progenitors: 132.0;Late primary spermatocytes: 91.7;Monocyte progenitors: 116.1;Renal collecting duct intercalated cells: 104.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA039408 Approved Supported "Nucleoplasm,Centrosome,Basal body" NA Yes "Cluster 24: Non-specific - Transcription" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 37: Neurons - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 27 "Centrosome, Basal body" Nucleoplasm "HPA039408: " "unprognostic (7.85e-2)" "unprognostic (1.03e-1)" "unprognostic (4.79e-2)" "unprognostic (2.76e-1)" "unprognostic (1.82e-1)" "unprognostic (3.57e-2)" "unprognostic (2.25e-1)" "unprognostic (2.43e-2)" "unprognostic (1.17e-2)" "unprognostic (5.27e-2)" "unprognostic (4.68e-2)" "unprognostic (6.32e-2)" "unprognostic (3.17e-2)" "unprognostic (1.68e-1)" "validated prognostic unfavorable (4.62e-4)" "validated prognostic unfavorable (1.25e-4)" "unprognostic (2.52e-2)" "unprognostic (1.49e-2)" "unprognostic (1.08e-3)" "unprognostic (2.48e-1)" "unprognostic (4.58e-3)" "unprognostic (1.43e-3)" "unprognostic (1.12e-2)" "unprognostic (3.41e-2)" "unprognostic (2.94e-2)" "unprognostic (4.57e-2)" "unprognostic (3.31e-1)" "unprognostic (2.79e-3)" "unprognostic (1.17e-1)" CEP162 "C6orf84, KIAA1009, QN1" ENSG00000135315 "Centrosomal protein 162" Q5TB80 6 84124241-84227643 "Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Early spermatids: 192.7;Ependymal cells: 172.6;Late primary spermatocytes: 187.7;Respiratory ciliated cells: 154.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030170, HPA030171, HPA030172, HPA030173" Supported Approved "Nucleoplasm,Centriolar satellite,Basal body,Cytosol,Connecting piece,Mid piece,Principal piece" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 46: Brainstem - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 35 "Nucleoplasm, Cytosol" "Centriolar satellite, Basal body, Connecting piece, Mid piece, Principal piece" "HPA030170: , HPA030171: , HPA030172: , HPA030173: " "unprognostic (1.15e-2)" "unprognostic (3.25e-2)" "unprognostic (5.71e-2)" "unprognostic (1.87e-2)" "unprognostic (1.35e-1)" "unprognostic (3.34e-1)" "unprognostic (2.84e-3)" "potential prognostic favorable (1.62e-5)" "unprognostic (3.00e-3)" "unprognostic (2.62e-1)" "unprognostic (2.94e-1)" "unprognostic (2.59e-1)" "unprognostic (2.37e-2)" "unprognostic (9.57e-2)" "unprognostic (2.53e-2)" "unprognostic (1.62e-1)" "unprognostic (1.98e-3)" "unprognostic (4.78e-3)" "unprognostic (8.55e-2)" "unprognostic (1.15e-1)" "unprognostic (3.28e-1)" "unprognostic (3.65e-2)" "unprognostic (1.40e-1)" CEP164 "KIAA1052, NPHP15" ENSG00000110274 "Centrosomal protein 164" Q9UPV0 11 117314557-117413266 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Cilium biogenesis/degradation, DNA damage, DNA repair, Mitosis" "Ciliopathy, Disease variant, Nephronophthisis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 623.1;Early spermatids: 342.9;Late spermatids: 441.4;Rod photoreceptor cells: 372.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037605, HPA037606, HPA061504" Uncertain Approved "Nucleoplasm,Vesicles,Primary cilium transition zone,Centrosome,Equatorial segment,Principal piece" NA NA "Cluster 32: Basophils - Transcription" "Cluster 8: Pancreas - Proteolysis" "Cluster 6: Non-specific - Immune response" "Cluster 24: Non-specific - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" 17 "Primary cilium transition zone, Centrosome, Principal piece" "Nucleoplasm, Vesicles, Equatorial segment" "HPA037605: , HPA037606: , HPA061504: " "unprognostic (1.72e-2)" "unprognostic (2.71e-2)" "unprognostic (2.67e-3)" "unprognostic (6.67e-3)" "unprognostic (2.95e-1)" "unprognostic (4.09e-1)" "unprognostic (1.70e-1)" "unprognostic (1.53e-2)" "unprognostic (3.72e-2)" "unprognostic (3.46e-2)" "unprognostic (2.99e-3)" "unprognostic (7.89e-2)" "unprognostic (6.65e-2)" "potential prognostic unfavorable (2.70e-4)" "unprognostic (1.16e-1)" "unprognostic (5.10e-2)" "unprognostic (1.41e-2)" "unprognostic (2.14e-1)" "unprognostic (3.52e-1)" "unprognostic (1.43e-1)" "unprognostic (1.71e-1)" "unprognostic (3.20e-1)" "potential prognostic unfavorable (7.98e-4)" "unprognostic (3.29e-1)" "unprognostic (2.11e-3)" "unprognostic (3.91e-3)" "unprognostic (6.33e-2)" "unprognostic (8.45e-2)" "unprognostic (1.23e-1)" "unprognostic (6.32e-2)" "unprognostic (3.58e-2)" CEP170 "FAM68A, KAB, KIAA0470" ENSG00000143702 "Centrosomal protein 170" Q5SW79 1 243124428-243255348 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "bone marrow: 49.6;brain: 22.8;testis: 85.1" "Cell type enhanced" "Detected in many" "Astrocytes: 117.7;Bergmann glia: 122.6;Brain excitatory neurons: 153.9;Brain inhibitory neurons: 147.0;Early spermatids: 211.3;Late spermatids: 1375.9;Microglia: 465.0;Oligodendrocyte progenitor cells: 157.7;Oligodendrocytes: 314.7;Other brain neurons: 137.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042151, HPA045597, HPA045787" Uncertain Supported "Centrosome,Basal body,Cytosol" NA No 12000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 39: Testis - Nuclear processes" "Cluster 30: White matter - Myelination" "Cluster 72: Neuronal - Signal transduction" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 76 "Centrosome, Basal body" Cytosol "HPA042151: , HPA045597: , HPA045787: " "unprognostic (1.13e-1)" "unprognostic (3.08e-1)" "unprognostic (3.18e-3)" "unprognostic (1.81e-2)" "unprognostic (7.89e-2)" "unprognostic (1.35e-1)" "unprognostic (2.22e-1)" "unprognostic (1.10e-3)" "unprognostic (5.20e-2)" "unprognostic (1.97e-1)" "potential prognostic favorable (3.75e-4)" "unprognostic (1.56e-1)" "unprognostic (4.99e-2)" "unprognostic (3.84e-2)" "unprognostic (2.35e-2)" "unprognostic (1.10e-1)" "unprognostic (5.38e-3)" "unprognostic (3.23e-3)" "unprognostic (1.53e-1)" "unprognostic (5.30e-2)" "potential prognostic unfavorable (6.50e-4)" "unprognostic (1.61e-2)" "potential prognostic unfavorable (7.93e-5)" "unprognostic (4.19e-2)" "unprognostic (2.78e-2)" "unprognostic (1.88e-3)" "unprognostic (9.95e-2)" "unprognostic (1.21e-1)" "unprognostic (3.26e-1)" "unprognostic (7.14e-3)" "unprognostic (2.00e-1)" CEP170B "Cep170R, FAM68C, KIAA0284" ENSG00000099814 "Centrosomal protein 170B" Q9Y4F5 14 104865268-104896747 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Colonocytes: 56.7;Cone photoreceptor cells: 113.9;Rod photoreceptor cells: 54.0;Tuft cells: 57.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000871, HPA001773, HPA059017" Enhanced Approved "Microtubule ends,Centrosome,Cytosol" NA NA "Cluster 64: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 79: Photoreceptor cells - Phototransduction" 19 "Microtubule ends" "Centrosome, Cytosol" "HPA000871: , HPA001773: , HPA059017: " "unprognostic (1.65e-1)" "unprognostic (1.69e-1)" "potential prognostic unfavorable (5.80e-4)" "unprognostic (7.59e-2)" "unprognostic (4.96e-2)" "unprognostic (7.27e-2)" "unprognostic (1.03e-1)" "unprognostic (3.14e-1)" "unprognostic (2.03e-1)" "unprognostic (2.26e-2)" "unprognostic (3.89e-2)" "unprognostic (8.82e-2)" "potential prognostic unfavorable (2.86e-4)" "unprognostic (2.56e-1)" "unprognostic (2.85e-1)" "unprognostic (1.61e-1)" "unprognostic (2.95e-1)" "unprognostic (1.06e-2)" "unprognostic (1.81e-1)" "unprognostic (1.56e-1)" "unprognostic (7.38e-2)" "unprognostic (1.01e-3)" "unprognostic (2.54e-1)" "unprognostic (1.23e-1)" "unprognostic (1.40e-1)" "unprognostic (1.08e-1)" "unprognostic (1.64e-1)" "unprognostic (5.48e-2)" "unprognostic (1.98e-1)" CEP19 "C3orf34, MGC14126" ENSG00000174007 "Centrosomal protein 19" Q96LK0 3 196706277-196712250 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" Obesity "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 50.7;Early primary spermatocytes: 43.4;Fallopian tube ciliated cells: 30.3;Late primary spermatocytes: 112.8;Neutrophils: 86.5;Respiratory ciliated cells: 38.2;Undifferentiated spermatogonia: 33.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 8 "basophil: 50.9;eosinophil: 58.8;neutrophil: 143.9" "Lineage enriched" "Detected in all" 13 "granulocytes: 143.9" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047614, HPA071138" Enhanced Supported "Nucleoplasm,Centrosome,Basal body,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 78: Brain - Neuronal signaling" "Cluster 17: Choroid plexus - Cilium" "Cluster 63: Non-specific - Protein processing" "Cluster 24: Neutrophils - Innate immunity signal integration" 64 "Centrosome, Basal body" "Nucleoplasm, Cytosol" "HPA047614: , HPA071138: " "unprognostic (1.11e-1)" "unprognostic (7.32e-2)" "unprognostic (1.81e-1)" "unprognostic (3.36e-2)" "unprognostic (2.17e-1)" "unprognostic (6.89e-3)" "unprognostic (7.93e-2)" "unprognostic (5.13e-2)" "unprognostic (1.80e-2)" "unprognostic (1.59e-1)" "unprognostic (2.66e-1)" "unprognostic (2.26e-1)" "unprognostic (2.98e-3)" "unprognostic (1.74e-1)" "unprognostic (1.56e-2)" "unprognostic (4.36e-3)" "potential prognostic favorable (4.16e-4)" "unprognostic (4.13e-1)" "unprognostic (1.90e-1)" "unprognostic (1.22e-1)" "unprognostic (2.96e-2)" "unprognostic (1.39e-1)" "unprognostic (1.92e-1)" "unprognostic (1.10e-1)" "unprognostic (5.76e-2)" "unprognostic (1.80e-1)" "unprognostic (1.62e-1)" "unprognostic (1.07e-1)" "unprognostic (1.77e-1)" CEP192 "FLJ10352, KIAA1569, PPP1R62" ENSG00000101639 "Centrosomal protein 192" Q8TEP8 18 12991362-13125052 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Sertoli cells: 291.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039392, HPA040503" Uncertain Uncertain "Centrosome,Basal body,Cytosol" Yes No "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 27: Non-specific - Cell proliferation" 36 Cytosol "Centrosome, Basal body" "HPA039392: , HPA040503: " "unprognostic (1.97e-1)" "unprognostic (8.73e-2)" "unprognostic (1.47e-1)" "unprognostic (9.92e-3)" "unprognostic (5.22e-2)" "unprognostic (3.86e-1)" "unprognostic (3.37e-2)" "potential prognostic favorable (3.27e-4)" "unprognostic (7.39e-2)" "potential prognostic unfavorable (7.33e-4)" "unprognostic (1.13e-3)" "unprognostic (6.20e-3)" "unprognostic (3.23e-2)" "unprognostic (7.40e-2)" "unprognostic (2.41e-1)" "unprognostic (1.77e-1)" "unprognostic (4.86e-2)" "unprognostic (1.45e-1)" "unprognostic (6.31e-2)" "unprognostic (2.86e-2)" "unprognostic (1.97e-2)" "unprognostic (1.27e-3)" "unprognostic (1.00e-1)" "unprognostic (1.84e-3)" "unprognostic (1.52e-1)" "unprognostic (2.23e-1)" "unprognostic (2.87e-1)" "unprognostic (2.43e-1)" "unprognostic (3.80e-3)" "unprognostic (1.73e-1)" CEP20 "C16orf63, DKFZp686N1651, FLJ31153, FOPNL, FOR20, PHSECRG2" ENSG00000133393 "Centrosomal protein 20" Q96NB1 16 15865719-15888625 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 304.8;Late primary spermatocytes: 155.9;Late spermatids: 736.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040599 Supported Supported "Nucleoplasm,Centriolar satellite,Centrosome,Basal body" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 24: Non-specific - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 5 "Centriolar satellite, Centrosome, Basal body" Nucleoplasm "HPA040599: " "unprognostic (7.04e-2)" "unprognostic (2.16e-1)" "unprognostic (3.57e-2)" "unprognostic (4.16e-3)" "unprognostic (8.39e-2)" "unprognostic (8.52e-2)" "unprognostic (5.58e-3)" "unprognostic (1.28e-1)" "potential prognostic unfavorable (2.31e-4)" "unprognostic (1.48e-3)" "unprognostic (2.20e-1)" "potential prognostic favorable (4.82e-4)" "unprognostic (1.41e-1)" "unprognostic (7.68e-2)" "unprognostic (1.77e-1)" "unprognostic (1.12e-1)" "unprognostic (5.06e-2)" "unprognostic (1.11e-1)" "unprognostic (2.10e-2)" "unprognostic (6.33e-3)" "unprognostic (4.86e-2)" "unprognostic (8.41e-2)" "unprognostic (1.59e-2)" "unprognostic (1.98e-1)" "unprognostic (2.72e-1)" "unprognostic (4.69e-2)" "unprognostic (2.79e-1)" "unprognostic (2.44e-2)" "unprognostic (2.28e-2)" CEP250 "C-NAP1, CEP2" ENSG00000126001 "Centrosomal protein 250" Q9BV73 20 35455164-35519280 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cilium biogenesis/degradation" "Cone-rod dystrophy, Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064875, HPA069380" Enhanced "Centrosome,Basal body" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 64: Non-specific - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 72: Neuronal - Signal transduction" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 18 Centrosome "Basal body" "HPA064875: , HPA069380: " "unprognostic (5.10e-2)" "unprognostic (2.13e-1)" "unprognostic (4.94e-3)" "unprognostic (1.65e-2)" "unprognostic (2.60e-1)" "unprognostic (2.08e-1)" "unprognostic (1.82e-1)" "unprognostic (4.10e-2)" "unprognostic (1.63e-1)" "unprognostic (2.08e-3)" "unprognostic (6.60e-2)" "unprognostic (5.42e-2)" "unprognostic (7.30e-2)" "potential prognostic unfavorable (1.12e-6)" "unprognostic (2.40e-2)" "unprognostic (4.96e-2)" "unprognostic (1.46e-3)" "unprognostic (1.80e-1)" "unprognostic (7.09e-3)" "unprognostic (9.73e-2)" "unprognostic (8.12e-2)" "potential prognostic favorable (8.74e-5)" "potential prognostic unfavorable (1.33e-4)" "unprognostic (1.60e-1)" "unprognostic (4.29e-2)" "unprognostic (1.89e-3)" "unprognostic (1.93e-1)" "unprognostic (1.75e-1)" "unprognostic (1.70e-1)" "potential prognostic unfavorable (7.76e-4)" "unprognostic (8.70e-2)" CEP290 "3H11Ag, BBS14, CT87, FLJ13615, JBTS5, KIAA0373, LCA10, MKS4, NPHP6, POC3, rd16, SLSN6" ENSG00000198707 "Centrosomal protein 290" O15078 12 88049016-88142099 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Transport" Activator "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Intellectual disability, Joubert syndrome, Leber congenital amaurosis, Meckel syndrome, Nephronophthisis, Obesity, Senior-Loken syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB029995, HPA043918, HPA064397" Approved Approved "Primary cilium,Centrosome,Basal body,Mid piece,Principal piece" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 9: Non-specific - Receptor signaling" "Cluster 38: Non-specific - Transcription" "Cluster 34: Ciliated cells - Cilia assembly & function" 44 "Centrosome, Basal body, Mid piece" "Primary cilium, Principal piece" "CAB029995: , HPA043918: , HPA064397: " "unprognostic (1.40e-1)" "unprognostic (2.92e-1)" "unprognostic (1.55e-2)" "unprognostic (8.61e-3)" "unprognostic (5.20e-2)" "unprognostic (1.60e-2)" "unprognostic (2.02e-1)" "unprognostic (3.15e-2)" "unprognostic (1.44e-1)" "unprognostic (2.87e-1)" "unprognostic (7.74e-2)" "unprognostic (9.68e-2)" "unprognostic (2.39e-1)" "unprognostic (9.30e-2)" "unprognostic (7.93e-2)" "unprognostic (4.19e-2)" "unprognostic (2.56e-1)" "unprognostic (4.92e-2)" "unprognostic (1.34e-1)" "unprognostic (6.40e-3)" "unprognostic (1.75e-1)" "unprognostic (3.46e-3)" "unprognostic (6.24e-2)" "unprognostic (2.30e-3)" "unprognostic (1.48e-2)" "unprognostic (8.33e-2)" "unprognostic (2.35e-1)" "unprognostic (1.67e-1)" "unprognostic (2.16e-3)" "unprognostic (1.29e-1)" CEP295 KIAA1731 ENSG00000166004 "Centrosomal protein 295" Q9C0D2 11 93661682-93730358 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 119.9;Oocytes: 156.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038595, HPA038596, HPA038597" Approved NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 24: Non-specific - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 6 "HPA038595: , HPA038596: , HPA038597: " "unprognostic (5.68e-3)" "unprognostic (2.64e-3)" "unprognostic (1.46e-2)" "unprognostic (2.38e-1)" "unprognostic (4.52e-2)" "unprognostic (6.11e-2)" "unprognostic (1.43e-2)" "unprognostic (7.15e-2)" "potential prognostic unfavorable (8.99e-5)" "unprognostic (2.57e-3)" "unprognostic (1.30e-1)" "unprognostic (7.47e-2)" "unprognostic (1.11e-3)" "unprognostic (5.16e-2)" "unprognostic (5.57e-2)" "unprognostic (1.52e-1)" "unprognostic (1.96e-1)" "unprognostic (2.10e-1)" "unprognostic (1.43e-1)" "unprognostic (6.08e-2)" "unprognostic (1.20e-3)" "unprognostic (1.25e-1)" "unprognostic (3.74e-3)" "unprognostic (5.37e-2)" "unprognostic (3.13e-3)" "unprognostic (1.31e-1)" "unprognostic (1.12e-1)" "unprognostic (1.50e-1)" "unprognostic (7.78e-2)" CEP295NL "DDC8, KIAA1731NL" ENSG00000178404 "CEP295 N-terminal like" Q96MC4 17 78890579-78903217 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "testis: 26.1" "Group enriched" "Detected in some" 8 "Early spermatids: 2.0;Late spermatids: 3.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "memory B-cell: 5.5;naive B-cell: 4.4" "Lineage enriched" "Detected in many" 5 "B-cells: 5.5" "Cancer enhanced" "Detected in some" "Myeloma: 4.4" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "HPA023609, HPA024619, HPA025717" Uncertain Approved Vesicles NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 57: Testis - Spermatogenesis" "Cluster 11: White matter - Signal transduction" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" Vesicles "HPA023609: , HPA024619: , HPA025717: " "unprognostic (2.91e-1)" "unprognostic (1.96e-2)" "potential prognostic unfavorable (5.86e-5)" "unprognostic (2.77e-3)" CEP350 "CAP350, KIAA0480" ENSG00000135837 "Centrosomal protein 350" Q5VT06 1 179954674-180114880 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 1017.4;Late spermatids: 1168.8;Neutrophil progenitors: 721.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028355, HPA028357, HPA030845, CAB079754" Enhanced Supported "Nucleoplasm,Centrosome,Basal body,End piece" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 67: Testis - Mixed function" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 41 "Nucleoplasm, Centrosome" "Basal body, End piece" "CAB079754: , HPA028355: , HPA028357: , HPA030845: " "unprognostic (1.88e-1)" "unprognostic (6.80e-2)" "unprognostic (2.42e-1)" "unprognostic (7.58e-2)" "unprognostic (1.95e-1)" "unprognostic (1.39e-1)" "unprognostic (1.20e-1)" "unprognostic (4.91e-2)" "unprognostic (2.09e-2)" "unprognostic (7.08e-3)" "potential prognostic favorable (1.54e-4)" "unprognostic (1.72e-2)" "unprognostic (3.02e-2)" "unprognostic (8.51e-2)" "unprognostic (1.95e-1)" "unprognostic (7.91e-2)" "unprognostic (4.82e-2)" "unprognostic (6.76e-2)" "unprognostic (6.58e-2)" "unprognostic (9.98e-2)" "unprognostic (7.90e-3)" "unprognostic (5.92e-2)" "unprognostic (5.99e-2)" "unprognostic (5.18e-2)" "unprognostic (4.88e-2)" "unprognostic (8.64e-2)" "unprognostic (3.73e-2)" "unprognostic (1.16e-1)" "unprognostic (3.15e-1)" "unprognostic (1.41e-2)" "unprognostic (1.38e-1)" CEP41 "DKFZp762H1311, FLJ22445, JBTS15, TSGA14" ENSG00000106477 "Centrosomal protein 41" Q9BYV8 7 130393771-130442433 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Transport" "Autism, Autism spectrum disorder, Ciliopathy, Joubert syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 47.3" "Group enriched" "Detected in many" 4 "Early spermatids: 562.2;Late primary spermatocytes: 451.1;Late spermatids: 205.5" "Cell type enhanced" "Detected in all" "ependymal cell: 105.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024090, HPA062216" Uncertain Supported "Primary cilium,Basal body" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 39: Non-specific - Transcription" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 1 "Primary cilium" "Basal body" "HPA024090: , HPA062216: " "unprognostic (7.96e-2)" "unprognostic (3.17e-2)" "unprognostic (9.52e-3)" "unprognostic (2.37e-3)" "unprognostic (5.47e-2)" "unprognostic (1.54e-1)" "unprognostic (1.50e-1)" "unprognostic (1.45e-1)" "potential prognostic unfavorable (7.46e-5)" "unprognostic (3.21e-2)" "unprognostic (2.27e-1)" "unprognostic (2.58e-2)" "potential prognostic unfavorable (1.32e-4)" "unprognostic (1.35e-2)" "unprognostic (3.06e-2)" "unprognostic (2.36e-1)" "unprognostic (1.28e-1)" "unprognostic (1.91e-1)" "unprognostic (2.05e-1)" "unprognostic (2.18e-2)" "unprognostic (1.57e-2)" "unprognostic (4.06e-1)" "potential prognostic favorable (6.64e-4)" "unprognostic (1.43e-1)" "unprognostic (1.73e-1)" "unprognostic (4.15e-2)" "unprognostic (6.91e-3)" "unprognostic (6.92e-2)" "unprognostic (7.18e-2)" CEP43 "FGFR1OP, FOP" ENSG00000213066 "Centrosomal protein 43" O95684 6 166999174-167052718 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 43.6" "Cell type enhanced" "Detected in many" "Astrocytes: 56.5;Brain excitatory neurons: 84.5;Brain inhibitory neurons: 88.5;Choroid plexus epithelial cells: 102.6;Distal convoluted tubule cells: 78.0;Early spermatids: 168.8;Ependymal cells: 247.4;Late primary spermatocytes: 64.6;Late spermatids: 173.0;Loop of henle epithelial cells: 73.8;Other brain neurons: 65.4;Podocytes: 67.1;Proximal tubule cells: 110.0;Renal collecting duct intercalated cells: 79.5;Renal collecting duct principal cells: 70.9;Renal connecting tubule cells: 59.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 30.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071876 Supported Supported "Centriolar satellite,Centrosome,Basal body" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 47: Testis - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 28: Non-specific - Nuclear processes" "Cluster 34: Ciliated cells - Cilia assembly & function" 28 "Centrosome, Basal body" "Centriolar satellite" "HPA071876: " "unprognostic (2.11e-2)" "unprognostic (2.44e-2)" "unprognostic (2.79e-2)" "unprognostic (1.34e-2)" "unprognostic (2.96e-3)" "unprognostic (1.21e-1)" "unprognostic (1.29e-1)" "unprognostic (2.34e-2)" "potential prognostic unfavorable (4.28e-4)" "unprognostic (3.95e-3)" "unprognostic (1.15e-2)" "unprognostic (3.13e-2)" "potential prognostic unfavorable (6.62e-4)" "unprognostic (3.77e-2)" "unprognostic (4.22e-2)" "unprognostic (2.13e-1)" "unprognostic (5.17e-2)" "unprognostic (7.72e-2)" "unprognostic (3.43e-1)" "unprognostic (2.41e-1)" "unprognostic (6.33e-3)" "unprognostic (1.23e-1)" "unprognostic (1.15e-3)" "unprognostic (9.50e-2)" "unprognostic (1.65e-1)" "unprognostic (3.63e-3)" "unprognostic (2.92e-1)" "unprognostic (2.41e-1)" "unprognostic (1.88e-1)" CEP44 KIAA1712 ENSG00000164118 "Centrosomal protein 44" Q9C0F1 4 174283730-174333380 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in all" 5 "Neuroblastoma: 125.8" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041515, HPA041835" Approved Approved "Basal body,Cytosol" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 40: Non-specific - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 58 "Basal body, Cytosol" "HPA041515: , HPA041835: " "unprognostic (1.04e-2)" "unprognostic (4.20e-2)" "unprognostic (4.53e-2)" "unprognostic (4.55e-2)" "unprognostic (1.66e-1)" "unprognostic (2.07e-1)" "unprognostic (2.03e-1)" "unprognostic (1.79e-1)" "unprognostic (6.53e-2)" "unprognostic (7.67e-3)" "unprognostic (6.73e-3)" "unprognostic (2.05e-1)" "potential prognostic unfavorable (2.16e-4)" "unprognostic (1.85e-1)" "unprognostic (1.72e-1)" "unprognostic (1.14e-1)" "unprognostic (1.20e-1)" "unprognostic (1.36e-1)" "unprognostic (2.15e-1)" "unprognostic (8.42e-2)" "unprognostic (3.82e-2)" "potential prognostic unfavorable (8.06e-5)" "unprognostic (1.99e-3)" "potential prognostic favorable (2.38e-4)" "unprognostic (1.49e-1)" "unprognostic (2.03e-2)" "unprognostic (1.91e-1)" "unprognostic (2.58e-1)" "unprognostic (3.56e-3)" "unprognostic (2.78e-2)" CEP55 "C10orf3, CT111, FLJ10540" ENSG00000138180 "Centrosomal protein 55" Q53EZ4 10 93496612-93529092 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 25.5;testis: 20.3" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 22.6;Early primary spermatocytes: 39.4;Early spermatids: 21.1;Enteric transient amplifying cells: 25.7;Esophageal basal cells: 26.9;Extravillous trophoblasts: 21.7;Gastric progenitor cells: 34.6;Hofbauer cells: 20.8;Late primary spermatocytes: 100.9;Megakaryocyte progenitors: 31.1;Monocyte progenitors: 149.7;Neutrophil progenitors: 26.7" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 8 "T-reg: 1.3" "Lineage enriched" "Detected in single" 14 "T-cells: 1.3" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Pituitary gland - Corticotropes, Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" HPA023430 Approved Uncertain "Plasma membrane,Midbody,Primary cilium,Centriolar satellite,Cytosol,Connecting piece,Principal piece" Yes Yes "Cluster 9: T-regs - Cell cycle regulation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 12: Non-specific - Vasculature" "Cluster 52: Non-specific - Mitochondria" "Cluster 27: Non-specific - Cell proliferation" 107 "Plasma membrane, Centriolar satellite" "Midbody, Primary cilium, Cytosol, Connecting piece, Principal piece" "HPA023430: " "unprognostic (1.91e-2)" "unprognostic (2.18e-1)" "unprognostic (1.13e-1)" "unprognostic (1.42e-1)" "unprognostic (7.07e-2)" "unprognostic (4.81e-2)" "unprognostic (8.32e-2)" "unprognostic (1.06e-1)" "unprognostic (9.69e-2)" "potential prognostic unfavorable (1.27e-5)" "validated prognostic unfavorable (1.09e-9)" "validated prognostic unfavorable (1.50e-7)" "potential prognostic unfavorable (1.22e-15)" "validated prognostic unfavorable (7.31e-9)" "validated prognostic unfavorable (4.22e-5)" "potential prognostic unfavorable (5.67e-5)" "unprognostic (1.15e-3)" "unprognostic (1.06e-2)" "unprognostic (3.68e-1)" "unprognostic (6.33e-2)" "unprognostic (2.29e-1)" "potential prognostic unfavorable (1.53e-5)" "unprognostic (1.33e-3)" "unprognostic (4.31e-2)" "unprognostic (2.25e-1)" "unprognostic (8.32e-2)" "unprognostic (5.79e-2)" "unprognostic (5.35e-3)" "unprognostic (7.12e-2)" "unprognostic (9.72e-2)" "unprognostic (2.75e-1)" CEP57 "KIAA0092, Translokin, TSP57" ENSG00000166037 "Centrosomal protein 57" Q86XR8 11 95789965-95832693 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 556.4;Late spermatids: 552.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018315, HPA066403" Approved Supported "Centriolar satellite,Centrosome,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 31: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 16 Centrosome "Centriolar satellite, Cytosol" "HPA018315: , HPA066403: " "potential prognostic favorable (8.14e-7)" "unprognostic (9.39e-2)" "unprognostic (9.44e-2)" "unprognostic (9.92e-2)" "unprognostic (2.20e-1)" "unprognostic (6.88e-2)" "unprognostic (1.44e-2)" "unprognostic (5.71e-3)" "unprognostic (3.22e-1)" "unprognostic (2.51e-1)" "potential prognostic favorable (2.03e-6)" "unprognostic (5.45e-3)" "unprognostic (6.48e-2)" "unprognostic (2.01e-2)" "unprognostic (7.56e-2)" "unprognostic (9.01e-2)" "unprognostic (2.16e-2)" "unprognostic (7.26e-2)" "unprognostic (2.09e-2)" "unprognostic (4.13e-1)" "unprognostic (2.40e-1)" "unprognostic (8.84e-3)" "unprognostic (6.49e-2)" "unprognostic (2.19e-2)" "potential prognostic favorable (2.69e-4)" "unprognostic (1.03e-2)" "unprognostic (4.14e-2)" "unprognostic (4.52e-2)" "unprognostic (3.01e-1)" "unprognostic (2.67e-3)" "unprognostic (3.46e-1)" CEP57L1 "bA487F23.2, C6orf182, MGC21731" ENSG00000183137 "Centrosomal protein 57 like 1" Q8IYX8 6 109095110-109174418 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Testis - Early spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040378 Approved NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 53: Neurons - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 28 "HPA040378: " "unprognostic (8.88e-3)" "unprognostic (2.08e-2)" "unprognostic (3.51e-2)" "unprognostic (3.02e-1)" "unprognostic (1.03e-1)" "unprognostic (9.56e-2)" "unprognostic (1.29e-1)" "unprognostic (2.21e-2)" "potential prognostic unfavorable (1.97e-4)" "unprognostic (5.47e-2)" "unprognostic (1.58e-2)" "unprognostic (2.81e-1)" "unprognostic (5.73e-3)" "unprognostic (2.95e-2)" "unprognostic (9.76e-3)" "unprognostic (8.00e-2)" "unprognostic (2.48e-1)" "unprognostic (5.55e-2)" "unprognostic (2.14e-2)" "unprognostic (1.26e-3)" "unprognostic (9.03e-2)" "potential prognostic unfavorable (1.97e-5)" "unprognostic (2.13e-1)" "unprognostic (1.21e-1)" "unprognostic (6.57e-2)" "unprognostic (3.20e-2)" "unprognostic (6.87e-2)" "unprognostic (2.66e-2)" "unprognostic (7.89e-3)" "unprognostic (1.18e-1)" CEP63 FLJ13386 ENSG00000182923 "Centrosomal protein 63" Q96MT8 3 134485699-134587789 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, Host-virus interaction, Mitosis" "Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 55.9;Bergmann glia: 65.5;Brain excitatory neurons: 62.9;Brain inhibitory neurons: 53.6;Choroid plexus epithelial cells: 48.9;Distal convoluted tubule cells: 49.0;Ependymal cells: 61.9;Loop of henle epithelial cells: 54.9;Microglia: 99.8;Oligodendrocyte progenitor cells: 79.7;Oligodendrocytes: 89.5;Other brain neurons: 46.9;Papillary tip epithelial cells: 44.9;Podocytes: 39.7;Proximal tubule cells: 42.6;Renal collecting duct intercalated cells: 39.1;Renal collecting duct principal cells: 44.0;Renal connecting tubule cells: 42.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 123.0" "Lineage enriched" "Detected in all" 6 "granulocytes: 123.0" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036264, HPA058154" Approved Supported "Nucleoplasm,Centrosome,Basal body,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 102: Non-specific - Mixed function" 68 "Centrosome, Basal body" "Nucleoplasm, Cytosol" "HPA036264: , HPA058154: " "unprognostic (6.77e-2)" "unprognostic (1.23e-1)" "unprognostic (3.14e-1)" "unprognostic (2.03e-2)" "unprognostic (2.29e-1)" "unprognostic (1.15e-1)" "unprognostic (1.20e-1)" "unprognostic (1.04e-1)" "unprognostic (2.73e-1)" "potential prognostic unfavorable (9.27e-4)" "potential prognostic favorable (1.02e-4)" "unprognostic (1.37e-2)" "unprognostic (4.34e-3)" "potential prognostic unfavorable (3.84e-4)" "unprognostic (3.36e-2)" "unprognostic (2.82e-1)" "unprognostic (9.11e-2)" "unprognostic (1.64e-1)" "unprognostic (1.03e-1)" "unprognostic (3.61e-1)" "unprognostic (4.44e-3)" "unprognostic (2.02e-1)" "potential prognostic unfavorable (6.24e-4)" "unprognostic (1.54e-1)" "unprognostic (9.07e-2)" "unprognostic (3.72e-1)" "unprognostic (4.72e-2)" "unprognostic (1.40e-1)" "unprognostic (2.08e-1)" "unprognostic (3.20e-1)" "unprognostic (1.43e-1)" CEP68 KIAA0582 ENSG00000011523 "Centrosomal protein 68" Q76N32 2 65056354-65087004 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epicardial cells: 177.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040493, HPA040620" Enhanced Approved "Nucleoplasm,Cell Junctions,Centriolar satellite,Basal body,Cytosol" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 8 "Nucleoplasm, Centriolar satellite" "Cell Junctions, Basal body, Cytosol" "HPA040493: , HPA040620: " "unprognostic (1.35e-1)" "unprognostic (1.09e-1)" "unprognostic (3.47e-1)" "unprognostic (4.22e-1)" "unprognostic (3.60e-1)" "unprognostic (1.62e-2)" "unprognostic (3.17e-2)" "potential prognostic favorable (4.29e-4)" "unprognostic (8.88e-3)" "unprognostic (1.86e-2)" "validated prognostic favorable (1.05e-8)" "validated prognostic favorable (2.28e-4)" "unprognostic (2.80e-1)" "unprognostic (5.06e-3)" "unprognostic (1.81e-1)" "unprognostic (2.10e-2)" "unprognostic (2.44e-1)" "unprognostic (6.63e-2)" "unprognostic (2.66e-2)" "unprognostic (3.65e-2)" "unprognostic (4.11e-2)" "unprognostic (3.21e-1)" "unprognostic (3.83e-1)" "unprognostic (1.73e-1)" "unprognostic (1.83e-2)" "unprognostic (6.45e-2)" "unprognostic (6.09e-2)" "unprognostic (1.85e-1)" "unprognostic (4.40e-1)" "unprognostic (3.47e-2)" "unprognostic (8.37e-2)" CEP70 "BITE, FLJ13036" ENSG00000114107 "Centrosomal protein 70" Q8NHQ1 3 138494344-138594538 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 260.8;Fallopian tube ciliated cells: 259.6;Late primary spermatocytes: 406.1;Late spermatids: 450.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "gdT-cell: 2.7;MAIT T-cell: 3.3;memory B-cell: 1.7;memory CD4 T-cell: 2.1;memory CD8 T-cell: 2.3;naive B-cell: 1.4;naive CD4 T-cell: 4.0;naive CD8 T-cell: 4.0;NK-cell: 2.2;T-reg: 1.3" "Group enriched" "Detected in many" 10 "B-cells: 1.7;NK-cells: 2.2;T-cells: 4.0" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells, Lung - Alveolar cells type 2, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036941, HPA036942" Enhanced Approved "Nucleoplasm,Primary cilium,Centrosome,Basal body,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 21: Testis - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 59: Leukemia - T-cell receptor" "Cluster 81: Alveolar cells - Lung function" 232 "Nucleoplasm, Primary cilium, Cytosol" "Centrosome, Basal body" "HPA036941: , HPA036942: " "unprognostic (6.92e-3)" "unprognostic (4.31e-2)" "unprognostic (2.47e-1)" "unprognostic (1.23e-2)" "unprognostic (5.04e-2)" "unprognostic (3.20e-1)" "unprognostic (8.63e-2)" "unprognostic (1.91e-2)" "unprognostic (1.20e-1)" "potential prognostic unfavorable (8.65e-4)" "unprognostic (1.91e-2)" "unprognostic (1.28e-1)" "unprognostic (4.87e-2)" "unprognostic (1.37e-1)" "unprognostic (4.08e-1)" "unprognostic (2.28e-2)" "unprognostic (4.64e-1)" "unprognostic (1.54e-1)" "unprognostic (1.30e-1)" "unprognostic (1.11e-1)" "unprognostic (1.37e-1)" "unprognostic (9.97e-3)" "unprognostic (1.25e-1)" "potential prognostic unfavorable (7.80e-4)" "unprognostic (2.69e-2)" "unprognostic (2.90e-2)" "unprognostic (2.34e-2)" "unprognostic (6.40e-2)" "unprognostic (3.10e-1)" "unprognostic (5.64e-3)" "unprognostic (1.72e-1)" CEP72 "FLJ10565, KIAA1519" ENSG00000112877 "Centrosomal protein 72" Q9P209 5 612340-667168 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 7.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 71.5;Early primary spermatocytes: 31.6;Epicardial cells: 40.9;Melanocytes: 181.5;Oocytes: 23.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 4.5" "Group enriched" "Detected in many" 4 "B-cells: 1.6;NK-cells: 4.5;T-cells: 1.7" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Region enriched" "Detected in many" 8 "cerebellum: 14.1" "Not detected" "Not detected" "HPA058235, HPA074879" Approved Supported "Centriolar satellite,Centrosome,Basal body" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 67: Testis - Mixed function" "Cluster 34: Non-specific - Mixed function" "Cluster 29: Non-specific - Unknown function" "Cluster 61: Schwann cells & Melanocytes - Mixed function" 33 "Centriolar satellite, Centrosome" "Basal body" "HPA058235: , HPA074879: " "unprognostic (2.88e-2)" "unprognostic (1.47e-1)" "unprognostic (2.54e-1)" "unprognostic (2.52e-1)" "unprognostic (6.03e-2)" "unprognostic (1.18e-1)" "unprognostic (1.78e-1)" "unprognostic (9.64e-2)" "unprognostic (6.19e-2)" "potential prognostic unfavorable (2.03e-5)" "unprognostic (3.38e-2)" "unprognostic (2.69e-1)" "unprognostic (3.76e-1)" "unprognostic (5.14e-3)" "unprognostic (1.93e-2)" "unprognostic (7.49e-2)" "unprognostic (1.03e-2)" "unprognostic (7.86e-2)" "unprognostic (1.67e-2)" "unprognostic (9.59e-2)" "unprognostic (5.85e-2)" "unprognostic (5.00e-2)" "unprognostic (8.24e-3)" "unprognostic (2.83e-2)" "unprognostic (2.25e-3)" "unprognostic (5.85e-2)" "unprognostic (3.48e-2)" "unprognostic (3.01e-2)" "unprognostic (1.59e-1)" "unprognostic (3.72e-2)" "unprognostic (6.48e-2)" CEP76 "C18orf9, FLJ12542, HsT1705" ENSG00000101624 "Centrosomal protein 76" Q8TAP6 18 12661833-12702777 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 293.0;Late primary spermatocytes: 76.3;Late spermatids: 72.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in all" 9 "cerebellum: 55.0" "Low region specificity" "Detected in all" HPA039395 Approved Uncertain "Nucleoplasm,Plasma membrane,Microtubules,Mitotic spindle,Primary cilium,Cytosol,Perinuclear theca,Flagellar centriole" Yes NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 35: Non-specific - DNA binding" "Cluster 13: Non-specific - Mixed function" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" 98 "Microtubules, Mitotic spindle, Primary cilium, Perinuclear theca, Flagellar centriole" "Nucleoplasm, Plasma membrane, Cytosol" "HPA039395: " "unprognostic (1.54e-1)" "unprognostic (1.82e-1)" "unprognostic (2.22e-1)" "unprognostic (5.18e-2)" "unprognostic (2.41e-1)" "unprognostic (3.36e-1)" "unprognostic (2.69e-1)" "unprognostic (2.78e-3)" "unprognostic (1.83e-1)" "potential prognostic unfavorable (9.48e-5)" "unprognostic (3.21e-3)" "unprognostic (2.97e-2)" "unprognostic (1.11e-1)" "unprognostic (5.31e-3)" "unprognostic (1.04e-3)" "unprognostic (2.07e-1)" "unprognostic (8.06e-2)" "unprognostic (1.96e-2)" "unprognostic (1.17e-3)" "unprognostic (1.32e-2)" "unprognostic (2.74e-1)" "unprognostic (2.53e-1)" "unprognostic (2.18e-2)" "unprognostic (3.89e-2)" "unprognostic (6.12e-2)" "unprognostic (9.98e-2)" "unprognostic (1.13e-2)" "unprognostic (3.33e-2)" "unprognostic (3.17e-1)" "unprognostic (1.63e-1)" "unprognostic (1.32e-1)" CEP78 "C9orf81, FLJ12643" ENSG00000148019 "Centrosomal protein 78" Q5JTW2 9 78236062-78279690 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Cone-rod dystrophy, Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 180.1;Early primary spermatocytes: 110.7;NK-cells: 164.1;Respiratory deuterosomal cells: 121.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 39.2" "Group enriched" "Detected in many" 5 "NK-cells: 39.2;T-cells: 18.4" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - NK-cells (Spleen), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048846 Approved NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 55: Non-specific - Transcription" "Cluster 3: Rhabdoid - Membrane components" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 14 "HPA048846: " "unprognostic (9.80e-3)" "unprognostic (2.73e-1)" "unprognostic (2.13e-1)" "unprognostic (1.15e-2)" "unprognostic (1.63e-1)" "unprognostic (1.52e-1)" "unprognostic (3.07e-1)" "unprognostic (1.08e-2)" "unprognostic (8.60e-2)" "unprognostic (2.45e-1)" "potential prognostic favorable (1.37e-4)" "unprognostic (1.15e-1)" "unprognostic (2.27e-1)" "potential prognostic unfavorable (1.00e-4)" "unprognostic (2.11e-2)" "unprognostic (3.83e-2)" "unprognostic (4.77e-2)" "unprognostic (6.26e-2)" "unprognostic (4.83e-2)" "unprognostic (1.94e-1)" "unprognostic (6.70e-2)" "unprognostic (7.01e-2)" "unprognostic (5.28e-2)" "unprognostic (9.11e-2)" "unprognostic (2.99e-2)" "unprognostic (1.17e-2)" "unprognostic (5.20e-2)" "unprognostic (1.21e-1)" "unprognostic (1.78e-1)" "unprognostic (8.47e-2)" "unprognostic (3.25e-1)" CEP83 "CCDC41, NPHP18, NY-REN-58" ENSG00000173588 "Centrosomal protein 83" Q9Y592 12 94306449-94459988 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Nephronophthisis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 640.9;Ependymal cells: 461.7;Fallopian tube ciliated cells: 261.4;Respiratory ciliated cells: 360.2" "Cell type enhanced" "Detected in all" "ependymal cell: 474.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038161 Approved Uncertain "Golgi apparatus,Vesicles,Primary cilium,Primary cilium transition zone" NA NA "Cluster 18: Non-specific - Translation" "Cluster 35: Non-specific - Mixed function" "Cluster 46: Brainstem - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 34: Ciliated cells - Cilia assembly & function" "Golgi apparatus, Vesicles, Primary cilium, Primary cilium transition zone" "HPA038161: " "unprognostic (3.04e-1)" "unprognostic (4.34e-2)" "unprognostic (8.18e-2)" "unprognostic (1.16e-1)" "unprognostic (2.80e-1)" "unprognostic (1.01e-1)" "unprognostic (2.85e-2)" "unprognostic (6.50e-2)" "unprognostic (3.44e-3)" "potential prognostic unfavorable (8.43e-5)" "unprognostic (6.76e-3)" "unprognostic (2.31e-1)" "unprognostic (9.93e-3)" "unprognostic (4.71e-2)" "unprognostic (4.57e-2)" "unprognostic (2.93e-2)" "unprognostic (2.22e-2)" "unprognostic (2.98e-2)" "unprognostic (7.21e-2)" "unprognostic (2.22e-2)" "unprognostic (1.45e-1)" "unprognostic (2.06e-2)" "unprognostic (2.45e-2)" "unprognostic (1.57e-1)" "unprognostic (1.97e-2)" "unprognostic (2.16e-1)" "unprognostic (1.16e-1)" "unprognostic (1.41e-1)" "unprognostic (7.47e-2)" CEP85 "CCDC21, DKFZP434L0117" ENSG00000130695 "Centrosomal protein 85" Q6P2H3 1 26234200-26278808 "Predicted intracellular proteins" "Chromosome partition" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 124.5;tongue: 61.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 147.7;Early primary spermatocytes: 85.6;Myonuclei: 320.5;Renal collecting duct intercalated cells: 81.7;Syncytiotrophoblasts: 94.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 19.2" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Kidney - Macrophages, Skeletal muscle - Skeletal myocytes, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028252 Approved Approved "Nucleoli,Golgi apparatus,Vesicles,Centrosome,Cytosol" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 16 "Nucleoli, Golgi apparatus" "Vesicles, Centrosome, Cytosol" "HPA028252: " "unprognostic (4.28e-1)" "unprognostic (2.61e-2)" "unprognostic (9.59e-2)" "unprognostic (4.81e-2)" "unprognostic (1.29e-2)" "unprognostic (2.15e-1)" "unprognostic (8.30e-3)" "unprognostic (2.23e-1)" "unprognostic (6.62e-2)" "unprognostic (4.05e-3)" "unprognostic (9.51e-2)" "unprognostic (8.81e-2)" "validated prognostic unfavorable (8.50e-9)" "validated prognostic unfavorable (3.84e-4)" "unprognostic (4.09e-1)" "unprognostic (7.64e-2)" "unprognostic (6.17e-2)" "potential prognostic favorable (1.45e-5)" "unprognostic (6.49e-2)" "unprognostic (1.31e-1)" "unprognostic (5.78e-3)" "unprognostic (1.54e-1)" "unprognostic (1.49e-1)" "unprognostic (1.85e-1)" "unprognostic (6.00e-2)" "unprognostic (1.20e-1)" "unprognostic (1.02e-2)" "unprognostic (2.01e-1)" "unprognostic (1.12e-2)" "unprognostic (3.88e-1)" CEP85L "bA57K17.2, C6orf204, NY-BR-15" ENSG00000111860 "Centrosomal protein 85 like" Q5SZL2 6 118460772-118710075 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 28.0" "Cell type enhanced" "Detected in many" "Bergmann glia: 619.2;Cardiomyocytes: 4033.8;Early spermatids: 619.8;Late spermatids: 1278.8;Myonuclei: 731.7" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 6.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029137, HPA029138, HPA029139" Uncertain NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 39: Testis - Nuclear processes" "Cluster 25: Non-specific - Transcription" "Cluster 59: Leukemia - T-cell receptor" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 12 "HPA029137: , HPA029138: , HPA029139: " "unprognostic (1.79e-2)" "unprognostic (1.41e-1)" "unprognostic (4.37e-2)" "unprognostic (3.73e-2)" "unprognostic (3.98e-2)" "unprognostic (1.80e-1)" "unprognostic (1.48e-2)" "unprognostic (1.13e-1)" "unprognostic (2.42e-1)" "unprognostic (7.34e-3)" "unprognostic (2.02e-1)" "unprognostic (1.76e-1)" "unprognostic (1.86e-2)" "unprognostic (2.81e-3)" "unprognostic (1.37e-2)" "unprognostic (2.83e-1)" "unprognostic (4.07e-2)" "unprognostic (4.40e-1)" "unprognostic (1.21e-2)" "unprognostic (3.80e-1)" "unprognostic (6.91e-2)" "unprognostic (1.09e-1)" CEP89 "CCDC123, FLJ14640" ENSG00000121289 "Centrosomal protein 89" Q96ST8 19 32875925-32971991 "Disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Liver - Vascular endothelial cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039382 Supported "Primary cilium,Centrosome,Basal body,Cytosol" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 17 Cytosol "Primary cilium, Centrosome, Basal body" "HPA039382: " "unprognostic (2.71e-2)" "unprognostic (3.82e-1)" "unprognostic (1.19e-2)" "unprognostic (2.96e-1)" "unprognostic (1.54e-1)" "unprognostic (1.38e-1)" "unprognostic (9.70e-2)" "unprognostic (4.06e-1)" "unprognostic (3.00e-2)" "unprognostic (4.35e-2)" "unprognostic (1.03e-1)" "unprognostic (5.48e-3)" "unprognostic (1.57e-3)" "unprognostic (7.12e-2)" "unprognostic (2.98e-1)" "unprognostic (2.04e-2)" "unprognostic (1.61e-2)" "unprognostic (1.29e-2)" "unprognostic (3.95e-2)" "unprognostic (1.40e-1)" "unprognostic (4.30e-2)" "potential prognostic unfavorable (1.49e-4)" "unprognostic (8.94e-2)" "unprognostic (1.05e-3)" "potential prognostic favorable (5.27e-4)" "unprognostic (1.23e-1)" "unprognostic (1.71e-1)" "unprognostic (3.00e-1)" "unprognostic (1.79e-1)" "unprognostic (2.93e-2)" CEP95 "CCDC45, DKFZp667E1824" ENSG00000258890 "Centrosomal protein 95" Q96GE4 17 64506865-64542461 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052426, HPA052428, HPA061371" Approved Approved "Centriolar satellite,Cytosol" NA No "Cluster 43: Non-specific - Transcription & Translation" "Cluster 40: Non-specific - Mixed function" "Cluster 46: Brainstem - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 31 "Centriolar satellite" Cytosol "HPA052426: , HPA052428: , HPA061371: " "unprognostic (1.50e-3)" "unprognostic (3.99e-2)" "unprognostic (1.53e-1)" "unprognostic (1.67e-1)" "unprognostic (1.15e-1)" "unprognostic (2.98e-1)" "unprognostic (4.45e-2)" "potential prognostic favorable (6.82e-4)" "unprognostic (7.53e-2)" "unprognostic (1.04e-1)" "unprognostic (1.52e-2)" "unprognostic (3.22e-2)" "unprognostic (1.44e-3)" "unprognostic (1.93e-1)" "unprognostic (2.25e-1)" "unprognostic (4.50e-2)" "unprognostic (1.86e-1)" "unprognostic (1.18e-2)" "unprognostic (6.27e-2)" "unprognostic (1.60e-2)" "unprognostic (1.26e-1)" "unprognostic (4.32e-3)" "unprognostic (5.84e-2)" "potential prognostic favorable (7.32e-5)" "unprognostic (1.69e-3)" "unprognostic (7.70e-2)" "unprognostic (8.08e-2)" "unprognostic (4.31e-1)" "unprognostic (1.40e-2)" "unprognostic (3.61e-2)" CEP97 "FLJ23047, LRRIQ2" ENSG00000182504 "Centrosomal protein 97" Q8IW35 3 101724534-101770562 "Essential proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation" Calmodulin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ependymal cells: 84.6;Oligodendrocyte progenitor cells: 75.9;Oligodendrocytes: 123.2;Respiratory ciliated cells: 92.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002980 Uncertain Approved "Centriolar satellite,Centrosome,Basal body,Cytosol" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 31 "Centriolar satellite, Centrosome, Cytosol" "Basal body" "HPA002980: " "unprognostic (5.71e-2)" "unprognostic (1.55e-2)" "unprognostic (2.06e-1)" "unprognostic (1.48e-1)" "unprognostic (7.96e-2)" "unprognostic (1.88e-1)" "unprognostic (1.32e-1)" "unprognostic (9.57e-3)" "unprognostic (1.36e-2)" "potential prognostic unfavorable (5.92e-5)" "unprognostic (7.32e-3)" "unprognostic (1.27e-1)" "unprognostic (1.68e-1)" "unprognostic (4.96e-1)" "unprognostic (1.84e-1)" "unprognostic (1.10e-1)" "unprognostic (8.91e-2)" "unprognostic (1.71e-2)" "unprognostic (2.96e-1)" "potential prognostic unfavorable (2.98e-4)" "unprognostic (5.04e-2)" "unprognostic (2.46e-2)" "unprognostic (1.37e-1)" "unprognostic (4.92e-3)" "unprognostic (1.35e-1)" "unprognostic (2.57e-1)" "unprognostic (4.87e-2)" "unprognostic (7.55e-2)" "unprognostic (1.44e-1)" "unprognostic (8.55e-2)" CEPT1 ENSG00000134255 "Choline/ethanolamine phosphotransferase 1" Q9Y6K0 1 111139479-111185104 "Enzymes, Essential proteins, Metabolic proteins, Predicted membrane proteins, Transporters" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 194.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 55: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 8 "unprognostic (6.13e-2)" "unprognostic (1.51e-1)" "unprognostic (7.37e-2)" "unprognostic (4.71e-2)" "unprognostic (1.73e-1)" "unprognostic (2.76e-1)" "unprognostic (1.68e-2)" "unprognostic (7.00e-2)" "unprognostic (1.70e-1)" "unprognostic (3.42e-1)" "potential prognostic favorable (2.96e-7)" "unprognostic (2.94e-2)" "unprognostic (1.60e-1)" "unprognostic (1.38e-2)" "unprognostic (1.53e-1)" "unprognostic (4.50e-2)" "unprognostic (1.50e-3)" "unprognostic (8.98e-3)" "unprognostic (6.01e-2)" "unprognostic (3.04e-1)" "unprognostic (2.15e-1)" "unprognostic (1.73e-2)" "unprognostic (3.74e-2)" "unprognostic (1.30e-1)" "unprognostic (1.30e-2)" "unprognostic (2.78e-1)" "unprognostic (3.52e-2)" "unprognostic (2.23e-2)" "unprognostic (7.69e-2)" "unprognostic (3.54e-1)" "unprognostic (2.30e-3)" CER1 DAND4 ENSG00000147869 "Cerberus 1, DAN family BMP antagonist" O95813 9 14719724-14722733 "Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "epididymis: 1.0" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "CGE interneuron: 1.1;lower rhombic lip: 1.1;splatter: 1.7" "Cancer enriched" "Detected in single" 77 "Testicular Germ Cell Tumor (TCGA): 25.8" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Bone cancer: 5.6;liver cancer: 5.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA019917 Uncertain "Secreted - unknown location" Cytokine NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 109: Neurons - Neuronal signaling" 4 "HPA019917: " "unprognostic (1.34e-2)" "unprognostic (6.18e-2)" CERCAM "CEECAM1, GLT25D3" ENSG00000167123 "Cerebral endothelial cell adhesion molecule" Q5T4B2 9 128411751-128437351 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 436.8;pituitary gland: 115.4" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 72.6;Extravillous trophoblasts: 94.5;Hepatic stellate cells: 148.5;Lactotrophs: 109.4;Oligodendrocytes: 679.2;Somatotrophs: 246.6;Thyrotrophs: 226.1" "Group enriched" "Detected in all" 13 "committed oligodendrocyte precursor: 350.6;oligodendrocyte: 743.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Adrenal gland - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblasts_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021657, HPA051595" Uncertain Approved "Nucleoplasm,Nucleoli,Cell Junctions" "Intracellular and membrane" "Cell adhesion" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 80: Oligodendrocytes - Myelination" 65 "Nucleoplasm, Nucleoli" "Cell Junctions" "HPA021657: , HPA051595: " "unprognostic (4.30e-1)" "unprognostic (4.55e-2)" "unprognostic (3.86e-2)" "potential prognostic unfavorable (3.63e-5)" "unprognostic (2.43e-3)" "unprognostic (9.38e-2)" "potential prognostic unfavorable (2.23e-4)" "unprognostic (1.71e-2)" "unprognostic (1.11e-2)" "unprognostic (8.86e-2)" "validated prognostic unfavorable (4.43e-11)" "validated prognostic unfavorable (9.12e-4)" "potential prognostic unfavorable (2.71e-4)" "unprognostic (1.04e-3)" "unprognostic (3.41e-1)" "unprognostic (8.38e-2)" "unprognostic (1.88e-3)" "unprognostic (1.02e-1)" "unprognostic (3.35e-1)" "validated prognostic unfavorable (6.94e-4)" "validated prognostic unfavorable (9.32e-4)" "unprognostic (1.40e-1)" "unprognostic (1.21e-1)" "unprognostic (1.13e-1)" "unprognostic (1.64e-2)" "unprognostic (2.69e-2)" "unprognostic (1.99e-1)" "unprognostic (1.81e-2)" "unprognostic (1.60e-1)" "potential prognostic unfavorable (7.67e-4)" "unprognostic (6.48e-2)" CERK "dA59H18.2, dA59H18.3, DKFZp434E0211, FLJ21430, FLJ23239, hCERK, KIAA1646, LK4" ENSG00000100422 "Ceramide kinase" Q8TCT0 22 46684410-46738252 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Innate lymphoid cells: 110.4;Lactotrophs: 143.6;Neutrophils: 122.0;Somatotrophs: 168.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pituitary gland - Lactotropes, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064699 Approved Vesicles NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 64: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 9: T-cells - Adaptive immunity: Regulation" 22 Vesicles "HPA064699: " "unprognostic (3.42e-1)" "unprognostic (1.55e-2)" "unprognostic (3.51e-2)" "unprognostic (6.00e-2)" "unprognostic (4.30e-2)" "unprognostic (8.19e-2)" "unprognostic (5.95e-2)" "unprognostic (1.36e-2)" "unprognostic (2.19e-3)" "unprognostic (5.41e-3)" "unprognostic (2.57e-3)" "potential prognostic favorable (8.78e-4)" "unprognostic (3.67e-1)" "unprognostic (2.41e-1)" "unprognostic (1.71e-1)" "unprognostic (8.58e-2)" "unprognostic (1.20e-1)" "unprognostic (2.54e-1)" "unprognostic (3.15e-2)" "unprognostic (2.21e-3)" "unprognostic (7.95e-2)" "potential prognostic favorable (1.82e-4)" "unprognostic (8.12e-2)" "unprognostic (9.87e-2)" "unprognostic (1.16e-1)" "unprognostic (2.94e-1)" "unprognostic (2.86e-1)" "unprognostic (1.82e-1)" "unprognostic (1.43e-1)" "unprognostic (1.06e-1)" "potential prognostic favorable (4.23e-4)" CERKL RP26 ENSG00000188452 "Ceramide kinase like" Q49MI3 2 181535041-181680665 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 7.7;kidney: 8.1;retina: 19.5" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 39.9;Choroid plexus epithelial cells: 67.0;Cone photoreceptor cells: 84.9;Endometrial ciliated cells: 145.7;Ependymal cells: 153.6;Epididymal efferent duct ciliated cells: 73.4;Fallopian tube ciliated cells: 98.0;Gonadotrophs: 46.3;Pancreatic islet cells: 39.1;Respiratory ciliated cells: 168.4;Rod photoreceptor cells: 131.1;Thymocytes: 69.4" "Group enriched" "Detected in many" 6 "choroid plexus epithelial cell: 59.6;ependymal cell: 169.1;upper rhombic lip: 126.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "cerebellum: 28.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 5.2" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Testis - Early spermatids, Thyroid gland - T-cells" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebellum: 18.5" "HPA035443, HPA035444, HPA043203" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 35: Non-specific - DNA binding" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 79: Photoreceptor cells - Phototransduction" 2 "Nucleoplasm, Cytosol" "HPA035443: , HPA035444: , HPA043203: " "unprognostic (5.23e-2)" "unprognostic (1.43e-1)" "unprognostic (9.61e-2)" "unprognostic (2.04e-1)" "potential prognostic favorable (3.65e-5)" "unprognostic (1.16e-3)" "unprognostic (7.84e-2)" "unprognostic (6.49e-2)" "unprognostic (4.67e-3)" "unprognostic (3.97e-1)" "unprognostic (4.47e-2)" "unprognostic (2.64e-2)" "unprognostic (3.14e-2)" "unprognostic (1.69e-1)" "unprognostic (9.74e-2)" "unprognostic (1.60e-1)" CERS1 "LAG1, LASS1, UOG1" ENSG00000223802 "Ceramide synthase 1" P27544 19 18868545-18896727 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Transferase "Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 163.8" "Cell type enhanced" "Detected in some" "Astrocytes: 377.9;Bergmann glia: 206.4;Brain excitatory neurons: 46.2;Brain inhibitory neurons: 49.8;Ependymal cells: 185.1;Late spermatids: 124.5;Oligodendrocyte progenitor cells: 68.0;Oligodendrocytes: 91.1;Other brain neurons: 46.8" "Cell type enhanced" "Detected in all" "astrocyte: 492.2" "Cancer enriched" "Detected in many" 6 "Glioblastoma Multiforme (TCGA): 238.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Pancreas - Alpha cells, Pituitary gland - Gonadotropes, Testis - Sertoli cells" "Low region specificity" "Detected in all" HPA045724 Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 28: Astrocytes - Homeostasis & neuron support" 1 "Endoplasmic reticulum" "HPA045724: " "unprognostic (6.97e-2)" "unprognostic (1.82e-2)" "potential prognostic favorable (3.31e-4)" "unprognostic (1.35e-1)" "unprognostic (5.18e-3)" "unprognostic (7.51e-2)" "unprognostic (9.66e-2)" "unprognostic (1.70e-2)" "unprognostic (1.11e-2)" "unprognostic (6.60e-2)" "unprognostic (1.84e-3)" "unprognostic (4.59e-2)" "unprognostic (1.65e-1)" "unprognostic (3.28e-3)" "unprognostic (2.26e-1)" "unprognostic (3.88e-1)" "unprognostic (8.92e-3)" "unprognostic (2.44e-3)" "unprognostic (5.93e-2)" "unprognostic (5.77e-2)" CERS2 "FLJ10243, LASS2, SP260" ENSG00000143418 "Ceramide synthase 2" Q96G23 1 150960583-150975003 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 683.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 219.8;Parietal cells: 153.8;Platelets: 400.4" "Cell type enhanced" "Detected in all" "oligodendrocyte: 90.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Macrophages, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027262, HPA078737" Approved Supported "Nuclear membrane,Endoplasmic reticulum" NA NA 27000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 76: Non-specific - Metabolism" "Cluster 30: White matter - Myelination" "Cluster 45: Non-specific - Nuclear processes" "Cluster 47: Platelets - Hemostasis" 49 "Nuclear membrane, Endoplasmic reticulum" "HPA027262: , HPA078737: " "unprognostic (1.57e-1)" "unprognostic (1.15e-1)" "unprognostic (6.42e-3)" "unprognostic (2.72e-1)" "unprognostic (4.61e-2)" "unprognostic (1.04e-1)" "unprognostic (1.61e-2)" "unprognostic (3.20e-3)" "unprognostic (3.80e-2)" "unprognostic (1.93e-2)" "unprognostic (7.77e-2)" "unprognostic (1.39e-1)" "unprognostic (2.65e-2)" "unprognostic (6.18e-2)" "unprognostic (9.47e-2)" "unprognostic (1.67e-1)" "unprognostic (3.51e-1)" "unprognostic (2.98e-2)" "unprognostic (2.12e-1)" "unprognostic (8.21e-2)" "unprognostic (5.10e-2)" "unprognostic (2.06e-1)" "unprognostic (1.98e-2)" "unprognostic (2.08e-1)" "unprognostic (1.81e-1)" "unprognostic (2.35e-1)" "unprognostic (2.57e-2)" "unprognostic (1.70e-1)" "unprognostic (1.07e-1)" CERS3 "LASS3, MGC27091" ENSG00000154227 "Ceramide synthase 3" Q8IU89 15 100400395-100544995 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Transferase Ichthyosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 53.1;skin 1: 61.6;vagina: 29.4" "Group enriched" "Detected in many" 4 "Esophageal apical cells: 819.2;Esophageal suprabasal cells: 357.9;Suprabasal keratinocytes: 241.9" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 19.2;Head and Neck Squamous Cell Carcinoma (TCGA): 43.0" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Esophageal cancer: 2.9;head and neck cancer: 10.6" "Minor Salivary Gland - Minor salivary gland basal cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA006092, HPA024356" Approved Supported Nucleoplasm NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 15: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 36 Nucleoplasm "HPA006092: , HPA024356: " "unprognostic (6.28e-2)" "unprognostic (4.28e-2)" "unprognostic (2.04e-1)" "unprognostic (1.86e-1)" "unprognostic (2.56e-1)" "unprognostic (9.77e-2)" "unprognostic (4.96e-2)" CERS4 "FLJ12089, LASS4, Trh1" ENSG00000090661 "Ceramide synthase 4" Q9HA82 19 8206736-8262421 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 283.2;Esophageal suprabasal cells: 194.9;Müller glia: 253.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Spleen - B-cells (Spleen), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033734, HPA054729" Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 11: White matter - Signal transduction" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 45 "Nucleoplasm, Vesicles" "CAB033734: , HPA054729: " "unprognostic (1.49e-3)" "potential prognostic unfavorable (9.34e-4)" "unprognostic (1.79e-2)" "unprognostic (1.50e-1)" "unprognostic (1.21e-2)" "unprognostic (3.05e-1)" "unprognostic (2.53e-1)" "potential prognostic favorable (6.31e-4)" "unprognostic (1.10e-1)" "potential prognostic favorable (9.06e-7)" "unprognostic (8.16e-2)" "unprognostic (2.70e-3)" "unprognostic (2.32e-1)" "potential prognostic favorable (2.15e-7)" "unprognostic (6.08e-2)" "unprognostic (1.93e-1)" "unprognostic (5.04e-2)" "unprognostic (2.74e-1)" "unprognostic (8.66e-2)" "potential prognostic favorable (1.30e-4)" "unprognostic (3.07e-2)" "unprognostic (7.40e-2)" "unprognostic (1.95e-1)" "unprognostic (1.67e-1)" "unprognostic (2.01e-2)" "unprognostic (2.20e-3)" "unprognostic (3.79e-1)" "unprognostic (2.26e-1)" "unprognostic (4.25e-2)" CERS5 "FLJ25304, LASS5, MGC45411, Trh4" ENSG00000139624 "Ceramide synthase 5" Q8N5B7 12 50129289-50167533 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Sphingolipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 187.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006780, HPA026589" Approved Approved "Nuclear membrane,Endoplasmic reticulum,Primary cilium" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 64: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 35: RS4;11 - Unknown function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 2 "Nuclear membrane" "Endoplasmic reticulum, Primary cilium" "HPA006780: , HPA026589: " "unprognostic (1.00e-1)" "unprognostic (8.66e-3)" "unprognostic (1.29e-2)" "unprognostic (2.89e-2)" "unprognostic (2.67e-3)" "unprognostic (5.18e-2)" "unprognostic (3.01e-1)" "unprognostic (1.22e-2)" "unprognostic (2.85e-2)" "potential prognostic unfavorable (1.77e-5)" "unprognostic (4.62e-3)" "unprognostic (5.32e-2)" "unprognostic (5.74e-3)" "unprognostic (5.26e-3)" "unprognostic (8.46e-2)" "potential prognostic favorable (7.64e-5)" "unprognostic (3.72e-1)" "unprognostic (7.77e-2)" "unprognostic (2.76e-1)" "unprognostic (1.58e-2)" "potential prognostic unfavorable (5.47e-4)" "unprognostic (4.17e-1)" "unprognostic (1.78e-2)" "unprognostic (2.15e-1)" "unprognostic (6.45e-2)" "unprognostic (1.52e-1)" "unprognostic (6.27e-2)" "unprognostic (9.76e-2)" "unprognostic (2.68e-2)" CERS6 LASS6 ENSG00000172292 "Ceramide synthase 6" Q6ZMG9 2 168456249-168775134 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Inflammatory response, Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Enteric stem cells: 774.5;Paneth cells: 823.8;Podocytes: 1192.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "plasmacytoid DC: 5.4" "Lineage enriched" "Detected in many" 5 "dendritic cells: 5.4" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044683 Approved NA No "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 14: Neurons - Synaptic function" "Cluster 24: Non-specific - Unknown function" "Cluster 82: Dendritic cells - Antigen presentation" 21 "HPA044683: " "unprognostic (7.59e-2)" "unprognostic (6.36e-2)" "unprognostic (1.10e-1)" "unprognostic (1.33e-1)" "unprognostic (2.40e-1)" "unprognostic (2.94e-1)" "unprognostic (1.54e-3)" "unprognostic (5.46e-2)" "unprognostic (9.00e-2)" "unprognostic (2.18e-3)" "unprognostic (9.96e-3)" "unprognostic (1.22e-2)" "potential prognostic unfavorable (3.34e-5)" "unprognostic (8.82e-3)" "unprognostic (3.57e-3)" "unprognostic (3.14e-2)" "unprognostic (7.31e-2)" "unprognostic (7.22e-2)" "unprognostic (1.96e-2)" "unprognostic (3.90e-2)" "unprognostic (1.27e-2)" "unprognostic (5.04e-2)" "unprognostic (7.95e-2)" "unprognostic (2.67e-2)" "unprognostic (5.05e-2)" "unprognostic (1.13e-1)" "unprognostic (3.02e-2)" "unprognostic (2.43e-1)" "unprognostic (9.18e-3)" CERT1 "CERT, COL4A3BP, GPBP, STARD11" ENSG00000113163 "Ceramide transporter 1" Q9Y5P4 5 75356345-75512138 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 573.4;Neutrophils: 715.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035645, HPA042608" Enhanced Enhanced "Nucleoplasm,Golgi apparatus" NA NA 37000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 69: Skin cancer - ECM organization" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 19 "Golgi apparatus" Nucleoplasm "HPA035645: , HPA042608: " "unprognostic (4.82e-3)" "unprognostic (1.38e-1)" "unprognostic (7.35e-2)" "unprognostic (8.70e-2)" "unprognostic (1.48e-1)" "unprognostic (8.20e-2)" "unprognostic (2.31e-1)" "unprognostic (7.10e-2)" "unprognostic (1.20e-2)" "potential prognostic favorable (4.56e-9)" "unprognostic (5.84e-3)" "unprognostic (5.51e-2)" "unprognostic (2.19e-1)" "unprognostic (1.52e-1)" "unprognostic (1.16e-1)" "unprognostic (3.21e-3)" "unprognostic (1.95e-1)" "unprognostic (1.02e-1)" "unprognostic (2.40e-2)" "unprognostic (9.43e-2)" "unprognostic (9.16e-2)" "unprognostic (1.24e-1)" "unprognostic (1.75e-1)" "unprognostic (2.23e-1)" "unprognostic (2.74e-1)" "unprognostic (7.73e-2)" "unprognostic (1.62e-1)" "unprognostic (1.90e-1)" "unprognostic (1.59e-1)" CES1 "CEH, CES1A1, CES1A2, CES2, HMSE, HMSE1, SES1" ENSG00000198848 "Carboxylesterase 1" P23141 16 55802851-55833337 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "liver: 2354.1" "Cell type enhanced" "Detected in some" "Conjunctival goblet cells: 14.6;Early spermatids: 5.7;Fallopian tube ciliated cells: 7.0;Fibroblasts: 6.5;Hepatic stellate cells: 6.5;Hepatocytes: 26.9;Monocyte progenitors: 15.8;monocytes: 6.6;Respiratory ciliated cells: 20.2;Smooth muscle cells: 9.5" "Cell type enhanced" "Detected in single" "fibroblast: 1.5" "Group enriched" "Detected in all" 8 "Liver Hepatocellular Carcinoma (TCGA): 1511.8;Lung Squamous Cell Carcinoma (TCGA): 489.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 16 "classical monocyte: 109.7;myeloid DC: 114.5" "Group enriched" "Detected in many" 22 "dendritic cells: 114.5;monocytes: 109.7" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 389.4;liver cancer: 290.7" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Fibroblasts, Liver - Hepatocytes, Skin - Fibroblasts_2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA012023, HPA046717" Enhanced Supported "Endoplasmic reticulum" "Intracellular and membrane" Enzyme No NA 35000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 8: Immune cells - Immune response" "Cluster 7: Liver cancer - Metabolism" "Cluster 108: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA012023: , HPA046717: " "unprognostic (8.95e-2)" "unprognostic (2.78e-2)" "unprognostic (1.30e-1)" "unprognostic (1.47e-2)" "unprognostic (1.97e-1)" "unprognostic (5.51e-2)" "unprognostic (4.36e-3)" "unprognostic (1.42e-2)" "unprognostic (2.84e-3)" "unprognostic (6.10e-3)" "unprognostic (1.21e-2)" "unprognostic (1.94e-3)" "unprognostic (4.40e-2)" "unprognostic (7.56e-2)" "unprognostic (5.12e-2)" "unprognostic (2.29e-1)" "unprognostic (4.06e-3)" "unprognostic (2.79e-1)" "unprognostic (1.51e-1)" "unprognostic (3.17e-2)" "unprognostic (1.84e-2)" "unprognostic (2.32e-1)" "unprognostic (1.66e-1)" "unprognostic (1.66e-1)" "unprognostic (2.05e-1)" "unprognostic (7.43e-2)" "unprognostic (8.09e-2)" "unprognostic (7.62e-2)" "unprognostic (1.74e-1)" "unprognostic (1.20e-2)" "unprognostic (1.81e-1)" CES2 "CE-2, CES2A1, iCE" ENSG00000172831 "Carboxylesterase 2" O00748 16 66934444-66945096 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 661.6;liver: 323.2" "Cell type enriched" "Detected in many" 4 "Enterocytes: 571.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 266.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "HPA018897, HPA074629" Enhanced Approved "Endoplasmic reticulum,Golgi apparatus,Cytosol" "Intracellular and membrane" Enzyme NA NA 3800000 "Cluster 33: Non-specific - ATP binding" "Cluster 77: Intestine - Digestion" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 1: Enterocytes - Absorption and Digestion" 6 "Golgi apparatus" "Endoplasmic reticulum, Cytosol" "HPA018897: , HPA074629: " "unprognostic (7.75e-2)" "unprognostic (3.77e-2)" "unprognostic (1.72e-1)" "unprognostic (1.66e-1)" "unprognostic (2.99e-1)" "unprognostic (1.72e-2)" "unprognostic (1.23e-1)" "unprognostic (1.92e-1)" "unprognostic (1.65e-1)" "unprognostic (7.83e-3)" "potential prognostic favorable (1.53e-7)" "unprognostic (8.63e-3)" "unprognostic (9.89e-3)" "unprognostic (8.53e-2)" "potential prognostic favorable (4.66e-5)" "unprognostic (4.99e-2)" "unprognostic (2.40e-2)" "unprognostic (1.27e-2)" "unprognostic (6.48e-2)" "unprognostic (1.69e-1)" "unprognostic (2.07e-2)" "unprognostic (3.75e-3)" "unprognostic (3.72e-2)" "unprognostic (1.64e-1)" "unprognostic (1.53e-1)" "unprognostic (6.93e-2)" "unprognostic (1.30e-1)" "unprognostic (8.30e-2)" "unprognostic (1.05e-1)" "unprognostic (1.90e-2)" "unprognostic (3.68e-3)" CES3 "ES31, FLJ21736" ENSG00000172828 "Carboxylesterase 3" Q6UWW8 16 66961245-66975149 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 35.5;liver: 51.1;skeletal muscle: 23.6" "Cell type enhanced" "Detected in many" "Breast lactating cells: 86.6;Colonocytes: 102.7;Enteric stem cells: 34.2;Enteric transient amplifying cells: 42.2;Enterocytes: 64.1;Goblet cells: 31.7;Hepatocytes: 63.7;Myonuclei: 40.0;Neuroendocrine cells: 24.9;Paneth cells: 27.1;Proximal tubule cells: 55.4;Tuft cells: 23.1" "Cell type enhanced" "Detected in many" "deep-layer near-projecting: 17.3" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 26.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Macrophages, Breast - Breast glandular cells (progenitors), Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA041008, HPA041307" Approved Approved "Nuclear membrane,Endoplasmic reticulum" "Intracellular and membrane" Enzyme NA NA 720000 "Cluster 19: Eosinophils - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 37: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" "Nuclear membrane, Endoplasmic reticulum" "HPA041008: , HPA041307: " "unprognostic (1.58e-1)" "unprognostic (1.24e-3)" "unprognostic (2.06e-1)" "unprognostic (2.16e-2)" "unprognostic (2.66e-2)" "unprognostic (4.92e-2)" "unprognostic (4.46e-2)" "unprognostic (3.33e-1)" "unprognostic (1.00e-2)" "unprognostic (7.34e-3)" "validated prognostic favorable (9.58e-7)" "validated prognostic favorable (1.75e-4)" "unprognostic (7.97e-2)" "potential prognostic favorable (9.48e-5)" "unprognostic (1.53e-3)" "unprognostic (5.56e-2)" "unprognostic (2.90e-2)" "unprognostic (4.63e-3)" "unprognostic (5.99e-3)" "unprognostic (2.28e-1)" "unprognostic (1.14e-1)" "unprognostic (9.68e-2)" "unprognostic (9.38e-2)" "unprognostic (5.27e-3)" "unprognostic (2.02e-1)" "unprognostic (4.82e-3)" "unprognostic (5.43e-1)" "unprognostic (2.49e-3)" "unprognostic (2.96e-1)" "unprognostic (4.74e-3)" CES4A "CES8, FLJ37464" ENSG00000172824 "Carboxylesterase 4A" Q5XG92 16 66988589-67010417 "Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 16.9" "Cell type enhanced" "Detected in many" "Breast lactating cells: 617.2;Epididymal efferent duct ciliated cells: 184.3;Fallopian tube ciliated cells: 138.1;Respiratory ciliated cells: 94.7;Thymic myoid cells: 210.7" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 9.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 3.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells, Pituitary gland - Somatotropes, Skin - Keratinocyte (granular)" "Not detected" "Not detected" HPA035701 Approved Approved Cytosol "Secreted - unknown location" Enzyme NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 2: Non-specific - Mixed function" "Cluster 34: Non-specific - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 4: Breast lactating luminal cells - Lactation" Cytosol "HPA035701: " "unprognostic (3.34e-2)" "unprognostic (1.45e-1)" "unprognostic (4.71e-2)" "unprognostic (4.90e-2)" "unprognostic (1.44e-1)" "unprognostic (6.50e-2)" "unprognostic (3.71e-3)" "unprognostic (4.09e-2)" "unprognostic (6.88e-3)" "unprognostic (1.19e-2)" "unprognostic (4.37e-2)" "unprognostic (1.93e-2)" "unprognostic (9.20e-2)" "unprognostic (2.75e-2)" "unprognostic (3.84e-2)" "unprognostic (2.30e-2)" CES5A "CAUXIN, CES4C1, CES5, CES7, FLJ31547" ENSG00000159398 "Carboxylesterase 5A" Q6NT32 16 55846154-55956031 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "epididymis: 63.7" "Cell type enriched" "Detected in some" 6 "Epididymal principal cells: 30.2" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adrenal gland - Adrenal medulla cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Thyrotropes" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "Secreted in male reproductive system" Enzyme NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 30: White matter - Myelination" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" "potential prognostic favorable (1.38e-4)" CETN1 "CEN1, CETN" ENSG00000177143 "Centrin 1" Q12798 18 580380-582114 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1230 "testis: 128.4" "Cell type enhanced" "Detected in some" "Early spermatids: 771.1;Late primary spermatocytes: 2025.8;Late spermatids: 494.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA028956, CAB037244, HPA069157" Enhanced Supported "Nucleoplasm,Flagellar centriole,Mid piece,Principal piece" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 5: Rhabdoid - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 23 "Nucleoplasm, Flagellar centriole" "Mid piece, Principal piece" "CAB037244: , HPA028956: , HPA069157: " CETN2 "CALT, CEN2" ENSG00000147400 "Centrin 2" P41208 X 152826994-152830757 "Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Mitosis, mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 233.9;fallopian tube: 229.2" "Group enriched" "Detected in many" 4 "Endometrial ciliated cells: 661.4;Epididymal efferent duct ciliated cells: 1013.6;Fallopian tube ciliated cells: 1356.9;Respiratory ciliated cells: 1032.0" "Cell type enriched" "Detected in all" 5 "ependymal cell: 192.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Smooth muscle cells, Lung - Respiratory ciliated cells, Spleen - Fibroblasts_1, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028956, HPA059330" Approved Supported "Nucleoplasm,Centrosome,Flagellar centriole,Mid piece,Principal piece" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 107: Ciliated cells - Cilia assembly & function" 58 "Nucleoplasm, Flagellar centriole" "Centrosome, Mid piece, Principal piece" "HPA028956: , HPA059330: " "unprognostic (1.16e-1)" "unprognostic (1.06e-1)" "unprognostic (2.57e-1)" "potential prognostic favorable (6.63e-4)" "unprognostic (1.26e-1)" "unprognostic (1.05e-1)" "unprognostic (1.30e-1)" "unprognostic (1.64e-2)" "unprognostic (1.05e-2)" "unprognostic (1.61e-2)" "unprognostic (4.88e-2)" "unprognostic (8.53e-2)" "unprognostic (1.32e-1)" "unprognostic (3.32e-3)" "unprognostic (1.17e-3)" "unprognostic (3.54e-1)" "unprognostic (3.23e-2)" "unprognostic (4.04e-2)" "unprognostic (1.38e-1)" "unprognostic (9.76e-3)" "unprognostic (4.04e-2)" "unprognostic (6.85e-2)" "unprognostic (2.93e-1)" "unprognostic (1.47e-1)" "unprognostic (5.39e-2)" "unprognostic (8.33e-2)" "unprognostic (6.47e-3)" "unprognostic (7.72e-3)" "unprognostic (1.15e-2)" "unprognostic (2.01e-1)" "unprognostic (1.79e-1)" CETN3 CEN3 ENSG00000153140 "Centrin 3" O15182 5 90392257-90409766 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 121.8" "Group enriched" "Detected in many" 7 "Early primary spermatocytes: 321.5;Late primary spermatocytes: 969.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035608, HPA063704" Enhanced Supported "Centrosome,Basal body" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 38 Centrosome "Basal body" "HPA035608: , HPA063704: " "unprognostic (1.04e-1)" "unprognostic (1.16e-1)" "unprognostic (5.32e-2)" "unprognostic (5.33e-2)" "unprognostic (6.12e-2)" "unprognostic (4.20e-3)" "unprognostic (1.78e-1)" "unprognostic (1.18e-1)" "unprognostic (1.98e-3)" "potential prognostic unfavorable (9.89e-5)" "potential prognostic favorable (3.07e-6)" "unprognostic (1.72e-1)" "unprognostic (2.75e-1)" "unprognostic (1.15e-3)" "potential prognostic unfavorable (5.41e-5)" "unprognostic (2.58e-1)" "unprognostic (3.49e-1)" "unprognostic (9.80e-2)" "unprognostic (2.49e-1)" "unprognostic (1.36e-1)" "unprognostic (4.01e-3)" "unprognostic (2.63e-2)" "unprognostic (1.37e-2)" "unprognostic (6.01e-2)" "unprognostic (9.42e-3)" "unprognostic (1.03e-2)" "unprognostic (9.04e-2)" "unprognostic (2.77e-1)" "unprognostic (1.72e-1)" "unprognostic (3.02e-1)" "unprognostic (1.18e-1)" CETP BPIFF ENSG00000087237 "Cholesteryl ester transfer protein" P11597 16 56961923-56983845 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" "Atherosclerosis, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "adipose tissue: 31.4;liver: 40.2;lymphoid tissue: 56.2;placenta: 34.0" "Cell type enriched" "Detected in some" 4 "Kupffer cells: 429.4" "Cell type enriched" "Detected in single" 9 "endothelial cell: 9.8" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 9.9" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.3;plasmacytoid DC: 3.2" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Leukemia: 1.4" "Secreted to blood" Transport NA NA 2470000000 140000000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" "unprognostic (1.32e-1)" "unprognostic (3.28e-2)" "unprognostic (1.34e-1)" "unprognostic (1.86e-2)" "unprognostic (1.36e-1)" "unprognostic (9.48e-2)" "potential prognostic favorable (1.15e-5)" "unprognostic (1.10e-3)" "unprognostic (2.53e-2)" "unprognostic (6.24e-2)" "unprognostic (1.95e-3)" "unprognostic (9.22e-2)" "unprognostic (6.42e-3)" "unprognostic (1.50e-2)" "unprognostic (2.20e-1)" "unprognostic (1.03e-2)" "unprognostic (1.04e-1)" "unprognostic (7.23e-3)" "unprognostic (2.90e-2)" "unprognostic (3.46e-2)" "unprognostic (7.70e-2)" "unprognostic (4.64e-3)" CFAP100 "CCDC37, FLJ40083, MIA1" ENSG00000163885 "Cilia and flagella associated protein 100" Q494V2 3 126394909-126436556 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 12.6;fallopian tube: 25.5;testis: 30.5" "Cell type enhanced" "Detected in many" "Early spermatids: 421.0;Endometrial ciliated cells: 157.0;Ependymal cells: 313.9;Fallopian tube ciliated cells: 142.8;Late primary spermatocytes: 102.0;Late spermatids: 1113.7;Respiratory ciliated cells: 280.2" "Cell type enriched" "Detected in all" 4 "ependymal cell: 306.8" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 4.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046354 Enhanced Approved "Mid piece,Principal piece" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 70: DU4475 - Unknown function" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" "Mid piece, Principal piece" "HPA046354: " "unprognostic (9.41e-2)" "unprognostic (2.67e-2)" "unprognostic (1.58e-2)" "unprognostic (6.40e-2)" "unprognostic (1.70e-1)" "unprognostic (3.54e-1)" "unprognostic (9.67e-3)" "unprognostic (1.91e-1)" CFAP107 "C1orf158, MGC35194" ENSG00000157330 "Cilia and flagella associated protein 107" Q8N1D5 1 12746200-12763699 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "choroid plexus: 44.0;fallopian tube: 25.1;testis: 46.3" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 127.7;Early spermatids: 172.2;Endometrial ciliated cells: 68.8;Ependymal cells: 137.1;Epididymal efferent duct ciliated cells: 53.7;Fallopian tube ciliated cells: 140.5;Late primary spermatocytes: 278.7;Late spermatids: 114.8;Respiratory ciliated cells: 145.7" "Group enriched" "Detected in some" 28 "choroid plexus epithelial cell: 90.7;ependymal cell: 141.6" "Group enriched" "Detected in some" 5 "Glioblastoma Multiforme (TCGA): 4.0;Ovary Serous Cystadenocarcinoma (TCGA): 2.4;Uterine Corpus Endometrial Carcinoma (TCGA): 9.4" "Region enhanced" "Detected in all" "choroid plexus: 39.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Skin - Sebaceous gland cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA028396 Uncertain Cytosol NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 34: Testis cancer - Unknown function" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" Cytosol "HPA028396: " "unprognostic (3.59e-1)" "unprognostic (1.47e-1)" "unprognostic (1.66e-1)" "unprognostic (1.29e-3)" "unprognostic (1.07e-2)" "unprognostic (3.59e-1)" "unprognostic (8.79e-3)" "unprognostic (3.62e-2)" "unprognostic (7.31e-2)" CFAP119 "C16orf93, CCDC189, MGC104706" ENSG00000196118 "Cilia and flagella associated protein 119" A1A4V9 16 30757423-30762221 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 36.5;testis: 22.1" "Cell type enhanced" "Detected in many" "Early spermatids: 182.1;Endometrial ciliated cells: 52.7;Epididymal efferent duct ciliated cells: 78.5;Fallopian tube ciliated cells: 79.5;Late primary spermatocytes: 156.9;Late spermatids: 465.7;Respiratory ciliated cells: 96.4" "Cell type enhanced" "Detected in many" "ependymal cell: 45.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 12.3" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041806, HPA046289, HPA075094" Approved Approved "Cytosol,Mid piece,Principal piece,End piece" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 1 "Cytosol, Mid piece, Principal piece, End piece" "HPA041806: , HPA046289: , HPA075094: " "unprognostic (5.37e-2)" "unprognostic (2.41e-1)" "unprognostic (2.28e-3)" "unprognostic (1.14e-1)" "unprognostic (8.78e-2)" "unprognostic (5.94e-3)" "unprognostic (8.93e-2)" "unprognostic (1.67e-2)" "unprognostic (4.33e-2)" "unprognostic (3.30e-3)" "unprognostic (8.06e-2)" "unprognostic (2.23e-1)" "unprognostic (1.12e-1)" "unprognostic (2.39e-2)" "unprognostic (2.45e-1)" "unprognostic (6.95e-2)" "unprognostic (1.78e-2)" "unprognostic (1.83e-2)" "unprognostic (7.62e-3)" "unprognostic (2.38e-1)" "unprognostic (2.81e-1)" "unprognostic (7.90e-2)" "unprognostic (3.91e-1)" "unprognostic (5.56e-2)" "unprognostic (1.45e-2)" "unprognostic (2.41e-1)" "unprognostic (5.50e-2)" "unprognostic (1.78e-1)" CFAP126 "C1orf192, Flattop, Fltp" ENSG00000188931 "Cilia and flagella associated protein 126" Q5VTH2 1 161364733-161367876 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 202.0;fallopian tube: 142.6" "Group enriched" "Detected in some" 5 "Endometrial ciliated cells: 238.8;Epididymal efferent duct ciliated cells: 477.2;Fallopian tube ciliated cells: 544.0;Late primary spermatocytes: 161.5;Respiratory ciliated cells: 388.2" "Group enriched" "Detected in some" 15 "choroid plexus epithelial cell: 22.4;ependymal cell: 64.5" "Cancer enhanced" "Detected in all" "Uterine Corpus Endometrial Carcinoma (TCGA): 57.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045904 Enhanced Approved "Vesicles,Plasma membrane,Primary cilium,Cytosol,Mid piece,Principal piece" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 45: Non-specific - Nuclear processes" "Cluster 107: Ciliated cells - Cilia assembly & function" "Plasma membrane, Primary cilium, Mid piece" "Vesicles, Cytosol, Principal piece" "HPA045904: " "unprognostic (1.47e-1)" "unprognostic (1.43e-2)" "unprognostic (8.82e-2)" "unprognostic (2.53e-1)" "unprognostic (1.95e-1)" "unprognostic (1.90e-1)" "unprognostic (1.07e-2)" "unprognostic (2.76e-2)" "potential prognostic unfavorable (1.71e-5)" "potential prognostic favorable (2.17e-6)" "unprognostic (1.56e-3)" "unprognostic (1.61e-1)" "unprognostic (2.04e-1)" "unprognostic (1.21e-1)" "unprognostic (1.52e-1)" "unprognostic (1.13e-1)" "unprognostic (3.84e-2)" "unprognostic (2.09e-1)" "unprognostic (1.37e-2)" "unprognostic (2.98e-1)" "potential prognostic unfavorable (1.68e-4)" "unprognostic (5.43e-2)" "unprognostic (6.45e-3)" "unprognostic (3.02e-2)" "unprognostic (8.17e-2)" "unprognostic (1.75e-1)" "unprognostic (2.20e-1)" "potential prognostic unfavorable (3.89e-4)" "unprognostic (4.44e-1)" CFAP141 C1orf189 ENSG00000163263 "Cilia and flagella associated protein 141" Q5VU69 1 154199085-154206333 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 12 "fallopian tube: 28.7;testis: 24.4" "Group enriched" "Detected in some" 4 "Early spermatids: 165.8;Endometrial ciliated cells: 89.3;Epididymal efferent duct ciliated cells: 180.9;Fallopian tube ciliated cells: 135.7;Late primary spermatocytes: 207.1;Respiratory ciliated cells: 157.3" "Cell type enriched" "Detected in some" 5 "ependymal cell: 12.8" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 6.3" "Region enhanced" "Detected in many" "midbrain: 6.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 107: Ciliated cells - Cilia assembly & function" 4 "unprognostic (6.77e-1)" "potential prognostic unfavorable (4.78e-4)" "unprognostic (4.41e-2)" "unprognostic (8.07e-2)" "unprognostic (1.69e-1)" "unprognostic (5.19e-2)" "unprognostic (4.26e-1)" CFAP157 C9orf117 ENSG00000160401 "Cilia and flagella associated protein 157" Q5JU67 9 127706988-127716002 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 36.8;fallopian tube: 48.1" "Group enriched" "Detected in many" 4 "Endometrial ciliated cells: 487.2;Ependymal cells: 675.9;Epididymal efferent duct ciliated cells: 604.4;Fallopian tube ciliated cells: 807.0;Respiratory ciliated cells: 900.6" "Cell type enriched" "Detected in many" 5 "ependymal cell: 694.6" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 6.7" "Region enhanced" "Detected in all" "choroid plexus: 76.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA021474, HPA021786" Enhanced Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 34: Ciliated cells - Cilia assembly & function" 1 "Plasma membrane, Cytosol" "HPA021474: , HPA021786: " "unprognostic (2.88e-1)" "unprognostic (2.38e-1)" "unprognostic (1.48e-1)" "unprognostic (1.15e-1)" "unprognostic (1.37e-1)" "unprognostic (5.08e-3)" "unprognostic (3.25e-2)" "unprognostic (4.33e-1)" "unprognostic (1.95e-1)" "unprognostic (1.04e-1)" "unprognostic (7.68e-2)" "potential prognostic favorable (3.77e-4)" "unprognostic (2.19e-2)" "unprognostic (9.45e-3)" "unprognostic (8.29e-2)" "unprognostic (1.98e-1)" CFAP161 "C15orf26, FLJ38615" ENSG00000156206 "Cilia and flagella associated protein 161" Q6P656 15 81007033-81149179 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "choroid plexus: 20.3;fallopian tube: 14.9;testis: 6.0" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 523.3;Endometrial secretory cells: 110.8;Retinal amacrine cells: 73.0;Retinal pigment epithelial cells: 191.8" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 388.7" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 3.2" "Region enriched" "Detected in all" 6 "choroid plexus: 80.5" "Immune cell enhanced" "Detected in single" "neutrophil: 1.1" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in single" 17 "Leukemia: 10.4" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA076975 Supported NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 103: Non-specific - Basic cellular processes" 12 "HPA076975: " "unprognostic (1.17e-1)" "unprognostic (1.23e-3)" "unprognostic (6.07e-2)" "unprognostic (6.68e-2)" "unprognostic (2.51e-1)" "unprognostic (3.06e-2)" "unprognostic (1.29e-1)" CFAP20 "C16orf80, fSAP23, GTL3" ENSG00000070761 "Cilia and flagella associated protein 20" Q9Y6A4 16 58113592-58129381 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 402.7;Late primary spermatocytes: 163.3;Late spermatids: 162.2" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 91.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018195 Uncertain Supported "Nucleoplasm,Equatorial segment,Principal piece" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 35: Non-specific - Mixed function" "Cluster 14: Neurons - Synaptic function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 37 "Nucleoplasm, Principal piece" "Equatorial segment" "HPA018195: " "unprognostic (5.18e-3)" "unprognostic (2.97e-3)" "unprognostic (2.97e-1)" "unprognostic (1.83e-1)" "unprognostic (6.38e-2)" "unprognostic (7.07e-2)" "unprognostic (7.71e-2)" "unprognostic (2.68e-3)" "unprognostic (1.23e-1)" "unprognostic (2.08e-3)" "unprognostic (2.37e-2)" "unprognostic (1.03e-1)" "unprognostic (1.50e-1)" "unprognostic (2.89e-1)" "unprognostic (8.16e-2)" "unprognostic (2.64e-1)" "unprognostic (1.24e-1)" "unprognostic (7.57e-2)" "unprognostic (1.79e-1)" "unprognostic (3.58e-2)" "unprognostic (4.60e-2)" "unprognostic (2.95e-1)" "unprognostic (2.28e-1)" "unprognostic (1.54e-1)" "unprognostic (5.65e-2)" "unprognostic (1.88e-1)" "unprognostic (2.27e-1)" "unprognostic (1.28e-1)" "unprognostic (3.85e-1)" CFAP206 "C6orf165, dJ382I10.1, FLJ25974" ENSG00000272514 "Cilia and flagella associated protein 206" Q8IYR0 6 87407972-87464465 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "fallopian tube: 21.0;testis: 55.2" "Group enriched" "Detected in some" 12 "Choroid plexus epithelial cells: 29.3;Ependymal cells: 105.6" "Cell type enriched" "Detected in many" 4 "ependymal cell: 116.5" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 4.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA044891 Approved NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 11: Neuronal - Sensory perception" "Cluster 34: Ciliated cells - Cilia assembly & function" 46 "HPA044891: " "unprognostic (1.14e-1)" "unprognostic (1.64e-2)" "unprognostic (3.70e-2)" "unprognostic (5.76e-2)" "unprognostic (1.24e-1)" "unprognostic (1.91e-1)" "unprognostic (2.34e-3)" "unprognostic (1.54e-1)" CFAP20DC "C3orf67, FLJ42117, FLJ42930" ENSG00000163689 "CFAP20 domain containing" Q6ZVT6 3 58717365-59050084 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "esophagus: 8.1;testis: 20.9" "Cell type enhanced" "Detected in many" "Early spermatids: 170.7;Ependymal cells: 97.3;Esophageal apical cells: 523.8;Esophageal suprabasal cells: 109.3;Gonadotrophs: 111.3;Late primary spermatocytes: 131.1;Late spermatids: 176.3;Ocular epithelial cells: 83.5;Respiratory ciliated cells: 126.1" "Cell type enhanced" "Detected in many" "ependymal cell: 113.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069696 Approved "Golgi apparatus" NA NA "Cluster 39: Testis - Nuclear processes" "Cluster 33: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 84: Apical squamous epithelium - Cornification" "Golgi apparatus" "HPA069696: " "unprognostic (1.27e-2)" "unprognostic (1.80e-1)" "unprognostic (8.51e-2)" "unprognostic (5.76e-3)" "unprognostic (2.60e-2)" "unprognostic (6.80e-2)" "unprognostic (3.35e-2)" "unprognostic (1.47e-2)" "unprognostic (7.40e-2)" "potential prognostic favorable (2.64e-4)" "potential prognostic unfavorable (8.20e-4)" "unprognostic (2.46e-2)" "potential prognostic unfavorable (9.65e-6)" "unprognostic (4.31e-2)" "unprognostic (3.24e-2)" "unprognostic (1.11e-2)" "unprognostic (2.87e-1)" "unprognostic (3.81e-2)" "potential prognostic unfavorable (4.47e-4)" "unprognostic (3.95e-1)" "unprognostic (1.30e-1)" "unprognostic (1.76e-1)" "unprognostic (6.20e-2)" "unprognostic (1.53e-1)" "unprognostic (5.71e-3)" CFAP210 "C2orf77, CCDC173, LOC129881" ENSG00000154479 "Cilia and flagella associated protein 210" Q0VFZ6 2 169645425-169694405 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "choroid plexus: 44.5;testis: 74.9" "Group enriched" "Detected in many" 4 "Early spermatids: 855.4;Endometrial ciliated cells: 438.3;Ependymal cells: 436.4;Epididymal efferent duct ciliated cells: 433.1;Fallopian tube ciliated cells: 575.3;Late primary spermatocytes: 1594.4;Respiratory ciliated cells: 679.8" "Group enriched" "Detected in many" 9 "choroid plexus epithelial cell: 151.9;ependymal cell: 472.0" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 4.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042995, HPA048454" Approved NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 107: Ciliated cells - Cilia assembly & function" "HPA042995: , HPA048454: " "unprognostic (3.34e-2)" "unprognostic (1.90e-1)" "unprognostic (9.12e-2)" "unprognostic (4.51e-2)" "unprognostic (2.48e-1)" "unprognostic (4.08e-2)" "unprognostic (1.27e-1)" "unprognostic (3.11e-2)" "unprognostic (5.01e-2)" "unprognostic (2.64e-2)" "unprognostic (4.53e-2)" CFAP221 "FAP221, PCDP1" ENSG00000163075 "Cilia and flagella associated protein 221" Q4G0U5 2 119544432-119662251 "Predicted intracellular proteins" "Cilium biogenesis/degradation" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 27.8;testis: 23.7" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 165.9;Distal convoluted tubule cells: 178.8;Early spermatids: 171.6;Endometrial ciliated cells: 265.2;Ependymal cells: 688.0;Epididymal efferent duct ciliated cells: 332.8;Fallopian tube ciliated cells: 448.4;Late primary spermatocytes: 203.2;Late spermatids: 489.2;Loop of henle epithelial cells: 209.4;Respiratory ciliated cells: 574.8" "Cell type enriched" "Detected in all" 4 "ependymal cell: 756.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney cancer: 3.3" "Adrenal gland - Adrenal cortex cells, Stomach - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA042501, HPA054164" Supported "Primary cilium,Primary cilium tip,Connecting piece,Flagellar centriole" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 15: Kidney cancer - Membrane components" "Cluster 34: Ciliated cells - Cilia assembly & function" "Primary cilium, Primary cilium tip, Connecting piece, Flagellar centriole" "HPA042501: , HPA054164: " "unprognostic (1.09e-1)" "unprognostic (6.35e-2)" "unprognostic (1.93e-1)" "unprognostic (4.34e-3)" "unprognostic (8.04e-2)" "potential prognostic unfavorable (6.89e-5)" "unprognostic (1.43e-3)" "unprognostic (8.40e-3)" "potential prognostic favorable (8.92e-4)" "unprognostic (7.61e-2)" "unprognostic (7.31e-2)" "unprognostic (3.34e-1)" "unprognostic (2.59e-1)" "unprognostic (2.20e-1)" "unprognostic (1.14e-1)" "unprognostic (1.17e-1)" "unprognostic (1.64e-1)" "unprognostic (9.23e-3)" "unprognostic (6.64e-2)" "unprognostic (1.10e-1)" CFAP251 "CaM-IP4, MGC33630, WDR66" ENSG00000158023 "Cilia and flagella associated protein 251" Q8TBY9 12 121918592-122003927 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 19.0;fallopian tube: 20.9;testis: 18.6" "Group enriched" "Detected in many" 4 "Choroid plexus epithelial cells: 151.3;Endometrial ciliated cells: 207.5;Ependymal cells: 363.9;Epididymal efferent duct ciliated cells: 169.1;Fallopian tube ciliated cells: 185.0;Respiratory ciliated cells: 444.3" "Cell type enhanced" "Detected in all" "ependymal cell: 379.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "plasmacytoid DC: 1.6" "Lineage enriched" "Detected in single" 8 "dendritic cells: 1.6" "Cancer enhanced" "Detected in many" "cervical cancer: 19.0" "Lung - Respiratory ciliated cells, Skin - Outer root sheath cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "HPA039902, HPA040005" Supported Supported "Mid piece,End piece" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 34: Ciliated cells - Cilia assembly & function" "Mid piece, End piece" "HPA039902: , HPA040005: " "potential prognostic unfavorable (2.38e-4)" "unprognostic (2.49e-2)" "unprognostic (3.75e-2)" "unprognostic (8.01e-2)" "unprognostic (2.16e-3)" "unprognostic (9.73e-2)" "unprognostic (4.15e-3)" "unprognostic (1.16e-1)" "unprognostic (2.66e-1)" "unprognostic (2.12e-3)" "unprognostic (2.23e-1)" "potential prognostic unfavorable (3.19e-4)" "unprognostic (2.87e-2)" "unprognostic (1.79e-1)" "unprognostic (3.00e-1)" "unprognostic (2.18e-1)" "unprognostic (1.84e-1)" "potential prognostic unfavorable (7.43e-5)" "unprognostic (1.48e-2)" "potential prognostic favorable (9.85e-6)" "unprognostic (1.52e-1)" "unprognostic (1.78e-1)" "unprognostic (1.83e-1)" "unprognostic (2.53e-2)" CFAP276 C1orf194 ENSG00000179902 "Cilia and flagella associated protein 276" Q5T5A4 1 109105951-109113857 "Disease related genes, Predicted intracellular proteins" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 28 "choroid plexus: 121.7;fallopian tube: 100.1;testis: 139.6" "Cell type enhanced" "Detected in many" "Early spermatids: 2229.4;Endometrial ciliated cells: 941.2;Epididymal efferent duct ciliated cells: 1878.2;Fallopian tube ciliated cells: 1665.5;Late primary spermatocytes: 1784.3;Late spermatids: 5594.8;Respiratory ciliated cells: 1019.7" "Group enriched" "Detected in many" 17 "choroid plexus epithelial cell: 48.8;ependymal cell: 156.9" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 19.2" "Region enriched" "Detected in all" 5 "choroid plexus: 27.7" "Immune cell enriched" "Detected in single" 6 "eosinophil: 2.1" "Lineage enriched" "Detected in single" 16 "granulocytes: 2.1" "Cancer enhanced" "Detected in single" "Bile duct cancer: 1.7" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA049684 Enhanced Approved "Mid piece,Principal piece,End piece" NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" "Mid piece, Principal piece, End piece" "HPA049684: " "unprognostic (7.26e-2)" "unprognostic (1.29e-1)" "unprognostic (2.18e-3)" "unprognostic (6.58e-2)" "unprognostic (2.51e-2)" "unprognostic (5.34e-3)" "unprognostic (2.92e-2)" "unprognostic (7.58e-2)" "unprognostic (3.65e-1)" "unprognostic (1.61e-1)" "unprognostic (8.10e-3)" "unprognostic (9.86e-2)" "unprognostic (3.23e-1)" "unprognostic (2.26e-1)" CFAP298 "C21orf48, C21orf59, CILD26, DNAAF16, FBB18, FLJ20467, Kur" ENSG00000159079 "Cilia and flagella associated protein 298" P57076 21 32592079-32612603 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 99.2;Endometrial ciliated cells: 101.2;Epididymal efferent duct ciliated cells: 128.0;Fallopian tube ciliated cells: 170.8;Late primary spermatocytes: 308.8;Respiratory ciliated cells: 134.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018453, HPA019055, HPA028849, CAB034170" Enhanced Supported "Nucleoplasm,Microtubules,Primary cilium transition zone,Centrosome,Basal body,Cytosol,Principal piece" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 47: Leukemia - Hemostasis" "Cluster 107: Ciliated cells - Cilia assembly & function" 11 "Basal body, Cytosol, Principal piece" "Nucleoplasm, Microtubules, Primary cilium transition zone, Centrosome" "CAB034170: , HPA018453: , HPA019055: , HPA028849: " "unprognostic (8.69e-2)" "unprognostic (7.76e-2)" "unprognostic (1.83e-1)" "unprognostic (5.60e-2)" "unprognostic (1.05e-1)" "unprognostic (2.91e-2)" "unprognostic (2.15e-1)" "unprognostic (3.51e-1)" "unprognostic (7.20e-2)" "unprognostic (8.54e-3)" "unprognostic (8.47e-2)" "unprognostic (1.07e-1)" "potential prognostic unfavorable (3.95e-4)" "unprognostic (8.86e-2)" "unprognostic (1.72e-1)" "unprognostic (4.40e-2)" "unprognostic (3.34e-2)" "unprognostic (1.22e-2)" "unprognostic (4.53e-2)" "unprognostic (2.71e-1)" "unprognostic (6.98e-3)" "unprognostic (1.77e-1)" "unprognostic (2.80e-1)" "unprognostic (3.60e-2)" "unprognostic (9.77e-2)" "unprognostic (1.96e-1)" "unprognostic (8.94e-3)" "unprognostic (2.69e-1)" "unprognostic (1.46e-1)" CFAP298-TCP10L "C21orf77, FLJ10932, LINC00846" ENSG00000265590 "CFAP298-TCP10L readthrough" 21 32402511-32612865 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 8 "Epicardial cells: 2829.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA019055, HPA028849" Approved Approved Microtubules,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 31: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" Cytosol Microtubules "HPA019055: , HPA028849: " "unprognostic (2.02e-1)" "unprognostic (2.19e-2)" "unprognostic (4.27e-1)" "unprognostic (1.72e-1)" "unprognostic (1.33e-1)" "unprognostic (3.46e-1)" "potential prognostic favorable (8.15e-5)" "unprognostic (4.51e-3)" "unprognostic (5.34e-2)" "unprognostic (1.63e-1)" "unprognostic (4.24e-3)" "unprognostic (1.09e-1)" "unprognostic (2.50e-3)" "unprognostic (1.80e-1)" "unprognostic (1.71e-1)" "unprognostic (8.55e-2)" "unprognostic (1.58e-2)" "unprognostic (6.44e-2)" "unprognostic (4.24e-1)" "unprognostic (1.78e-1)" "unprognostic (9.11e-3)" "unprognostic (2.21e-1)" "unprognostic (3.55e-1)" "unprognostic (4.32e-1)" "unprognostic (2.57e-2)" "unprognostic (2.89e-1)" "unprognostic (8.18e-2)" "unprognostic (5.40e-2)" "unprognostic (8.77e-2)" CFAP299 C4orf22 ENSG00000197826 "Cilia and flagella associated protein 299" Q6V702 4 80335730-80963750 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "fallopian tube: 18.6;testis: 25.6" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 388.6;Endometrial ciliated cells: 1250.7;Ependymal cells: 5123.3;Epididymal efferent duct ciliated cells: 1020.3;Fallopian tube ciliated cells: 1252.2;Respiratory ciliated cells: 3061.6;Respiratory deuterosomal cells: 401.2" "Cell type enriched" "Detected in all" 9 "ependymal cell: 5547.0" "Cancer enhanced" "Detected in single" "Uterine Corpus Endometrial Carcinoma (TCGA): 1.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 2.3" "Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA043383 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 34: Ciliated cells - Cilia assembly & function" 3 "Plasma membrane, Cytosol" "HPA043383: " "unprognostic (5.21e-1)" CFAP300 "C11orf70, DNAAF17, FBB5, MGC13040" ENSG00000137691 "Cilia and flagella associated protein 300" Q9BRQ4 11 102047437-102084554 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 23.0;fallopian tube: 27.4;testis: 28.2" "Group enriched" "Detected in many" 4 "Early primary spermatocytes: 171.6;Early spermatids: 317.0;Endometrial ciliated cells: 157.0;Ependymal cells: 145.6;Epididymal efferent duct ciliated cells: 147.3;Fallopian tube ciliated cells: 228.0;Late primary spermatocytes: 553.9;Respiratory ciliated cells: 339.7" "Group enriched" "Detected in many" 4 "choroid plexus epithelial cell: 64.8;ependymal cell: 170.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038585 Enhanced Approved "Primary cilium,Centrosome" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 107: Ciliated cells - Cilia assembly & function" "Primary cilium, Centrosome" "HPA038585: " "unprognostic (2.67e-2)" "unprognostic (5.31e-2)" "unprognostic (1.58e-1)" "unprognostic (3.00e-1)" "unprognostic (5.53e-3)" "unprognostic (1.13e-1)" "unprognostic (1.02e-2)" "unprognostic (1.66e-1)" "unprognostic (9.81e-2)" "potential prognostic unfavorable (1.43e-5)" "unprognostic (1.44e-1)" "unprognostic (3.10e-2)" "unprognostic (8.70e-2)" "unprognostic (1.06e-1)" "unprognostic (2.11e-1)" "unprognostic (2.26e-2)" "unprognostic (1.52e-2)" "unprognostic (3.34e-1)" "unprognostic (7.62e-2)" "unprognostic (4.16e-2)" "unprognostic (6.62e-2)" "unprognostic (8.22e-2)" "unprognostic (2.28e-1)" "unprognostic (8.91e-3)" "unprognostic (4.40e-2)" "unprognostic (6.30e-2)" "unprognostic (4.70e-2)" CFAP36 "BARTL1, CCDC104, MGC15407" ENSG00000163001 "Cilia and flagella associated protein 36" Q96G28 2 55519604-55545079 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 1353.3;Late primary spermatocytes: 1182.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Skin - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008994, HPA017061" Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Nuclear bodies,Primary cilium,Cytosol" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 6 Nucleoplasm "Nucleoli fibrillar center, Nuclear bodies, Primary cilium, Cytosol" "HPA008994: , HPA017061: " "unprognostic (9.47e-2)" "unprognostic (6.63e-2)" "unprognostic (1.93e-2)" "unprognostic (1.62e-1)" "unprognostic (1.56e-1)" "unprognostic (2.42e-2)" "unprognostic (4.82e-3)" "unprognostic (6.25e-2)" "unprognostic (1.99e-3)" "potential prognostic favorable (2.19e-4)" "unprognostic (4.74e-2)" "unprognostic (2.17e-3)" "unprognostic (5.57e-3)" "unprognostic (1.89e-1)" "unprognostic (3.63e-2)" "unprognostic (1.83e-1)" "unprognostic (1.88e-1)" "unprognostic (1.25e-1)" "unprognostic (1.38e-2)" "unprognostic (9.17e-2)" "unprognostic (7.38e-3)" "unprognostic (8.55e-2)" "unprognostic (2.01e-1)" "unprognostic (2.28e-1)" "unprognostic (1.81e-2)" "unprognostic (9.32e-2)" "unprognostic (2.10e-2)" "unprognostic (9.71e-2)" "unprognostic (4.05e-2)" CFAP410 "A2, C21orf2, LRRC76, YF5" ENSG00000160226 "Cilia and flagella associated protein 410" O43822 21 44328944-44339402 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, DNA damage" "Ciliopathy, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 60.0;Late primary spermatocytes: 93.0;Late spermatids: 320.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030284, CAB034126, CAB034128" Supported Supported "Golgi apparatus,Primary cilium transition zone,Basal body,Cytosol" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 23 "Golgi apparatus, Primary cilium transition zone, Cytosol" "Basal body" "CAB034126: , CAB034128: , HPA030284: " "unprognostic (4.49e-2)" "unprognostic (1.38e-1)" "unprognostic (1.52e-1)" "unprognostic (1.42e-1)" "unprognostic (1.98e-1)" "unprognostic (2.15e-2)" "unprognostic (2.86e-1)" "unprognostic (4.68e-2)" "unprognostic (5.30e-2)" "unprognostic (6.31e-3)" "unprognostic (2.87e-2)" "potential prognostic favorable (6.95e-5)" "unprognostic (1.73e-1)" "unprognostic (4.31e-2)" "unprognostic (1.77e-1)" "unprognostic (5.70e-2)" "unprognostic (1.78e-2)" "unprognostic (1.51e-1)" "unprognostic (1.95e-1)" "potential prognostic favorable (2.74e-5)" "unprognostic (1.29e-3)" "unprognostic (5.20e-2)" "unprognostic (1.87e-1)" "unprognostic (5.04e-3)" "unprognostic (2.62e-2)" "unprognostic (3.72e-1)" "unprognostic (1.52e-1)" "unprognostic (5.91e-2)" "unprognostic (2.77e-2)" CFAP418 "BBS21, C8orf37, CORD16, FAP418, FLJ30600, MOT25, RP64" ENSG00000156172 "Cilia and flagella associated protein 418" Q96NL8 8 95244913-95269201 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Bardet-Biedl syndrome, Ciliopathy, Cone-rod dystrophy, Disease variant, Obesity, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 31.9;Ependymal cells: 44.9;Respiratory ciliated cells: 25.8" "Cell type enhanced" "Detected in all" "ependymal cell: 56.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024198 Approved Approved "Vesicles,Plasma membrane,Cell Junctions,Primary cilium,Centrosome" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 65: Brain - Transcription" "Cluster 46: Brainstem - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 34: Ciliated cells - Cilia assembly & function" 3 "Plasma membrane, Primary cilium" "Vesicles, Cell Junctions, Centrosome" "HPA024198: " "unprognostic (4.46e-1)" "unprognostic (1.41e-1)" "unprognostic (2.57e-1)" "unprognostic (9.73e-2)" "unprognostic (6.11e-2)" "unprognostic (4.35e-2)" "unprognostic (1.87e-3)" "unprognostic (4.84e-1)" "unprognostic (2.43e-2)" "unprognostic (1.18e-1)" "potential prognostic favorable (1.54e-4)" "unprognostic (1.15e-1)" "unprognostic (1.97e-2)" "unprognostic (2.88e-1)" "unprognostic (7.83e-3)" "unprognostic (2.39e-1)" "unprognostic (2.65e-1)" "unprognostic (3.11e-1)" "unprognostic (2.39e-1)" "unprognostic (3.72e-1)" "unprognostic (1.02e-2)" "unprognostic (3.60e-3)" "unprognostic (1.06e-1)" "unprognostic (2.31e-2)" "unprognostic (6.22e-2)" "unprognostic (6.28e-2)" "unprognostic (5.52e-2)" "unprognostic (1.93e-1)" "unprognostic (5.91e-2)" "unprognostic (2.05e-1)" CFAP43 "bA373N18.2, C10orf79, FLJ22944, FLJ36006, WDR96" ENSG00000197748 "Cilia and flagella associated protein 43" Q8NDM7 10 104129888-104232364 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "choroid plexus: 94.1;fallopian tube: 46.0;testis: 53.6" "Group enriched" "Detected in many" 6 "Choroid plexus epithelial cells: 932.0;Endometrial ciliated cells: 655.2;Ependymal cells: 1937.6;Epididymal efferent duct ciliated cells: 648.4;Fallopian tube ciliated cells: 811.8;Respiratory ciliated cells: 1174.3" "Group enriched" "Detected in all" 17 "choroid plexus epithelial cell: 805.7;ependymal cell: 2100.9" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 10.1" "Region enhanced" "Detected in all" "choroid plexus: 166.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose visceral - Mesothelial cells, Colon - Enteric glia cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "midbrain: 7.6" HPA038127 Approved "Nucleoplasm,Nuclear membrane,Cytosol,Flagellar centriole,Mid piece,Principal piece" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" "Nucleoplasm, Flagellar centriole" "Nuclear membrane, Cytosol, Mid piece, Principal piece" "HPA038127: " "unprognostic (1.40e-1)" "unprognostic (3.05e-3)" "unprognostic (2.63e-1)" "unprognostic (7.87e-2)" "unprognostic (1.58e-1)" "unprognostic (2.42e-2)" "unprognostic (2.25e-3)" "unprognostic (3.52e-2)" "unprognostic (1.37e-1)" "unprognostic (1.57e-1)" "unprognostic (2.54e-1)" "unprognostic (3.59e-2)" "unprognostic (3.07e-1)" "unprognostic (6.81e-2)" "unprognostic (1.30e-3)" "unprognostic (3.52e-3)" "unprognostic (2.18e-1)" "unprognostic (4.75e-2)" "unprognostic (5.15e-2)" "unprognostic (4.00e-3)" "unprognostic (6.94e-3)" CFAP44 "FLJ11142, WDR52" ENSG00000206530 "Cilia and flagella associated protein 44" Q96MT7 3 113286930-113441610 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Choroid plexus epithelial cells: 609.4;Ependymal cells: 1353.3" "Group enriched" "Detected in all" 7 "choroid plexus epithelial cell: 526.2;ependymal cell: 1447.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "midbrain: 18.5" HPA067258 Uncertain NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 56: Non-specific - Sensory perception" "Cluster 34: Ciliated cells - Cilia assembly & function" 1 "HPA067258: " "unprognostic (1.55e-1)" "unprognostic (5.27e-2)" "unprognostic (1.27e-1)" "unprognostic (1.54e-1)" "unprognostic (1.10e-2)" "unprognostic (5.51e-2)" "unprognostic (5.30e-2)" "unprognostic (4.13e-2)" "unprognostic (1.18e-2)" "unprognostic (4.32e-2)" "unprognostic (1.24e-2)" "unprognostic (1.23e-1)" "unprognostic (4.11e-2)" CFAP45 "CCDC19, NESG1" ENSG00000213085 "Cilia and flagella associated protein 45" Q9UL16 1 159872364-159900165 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant, Heterotaxy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "choroid plexus: 35.2;fallopian tube: 42.1;testis: 26.7" "Cell type enhanced" "Detected in many" "Early spermatids: 254.8;Endometrial ciliated cells: 136.9;Ependymal cells: 144.2;Epididymal efferent duct ciliated cells: 180.9;Fallopian tube ciliated cells: 310.3;Late primary spermatocytes: 211.1;Late spermatids: 61.4;Respiratory ciliated cells: 343.8" "Cell type enriched" "Detected in some" 5 "ependymal cell: 158.8" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 19.4" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 8 "eosinophil: 3.0;neutrophil: 2.4" "Lineage enriched" "Detected in single" 9 "granulocytes: 3.0" "Cancer enhanced" "Detected in many" "Bile duct cancer: 7.3" "Kidney - Podocytes, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA042204, HPA043618" Enhanced Uncertain "Nucleoplasm,Basal body,Cytosol,Mid piece,Principal piece,End piece" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" 1 "Nucleoplasm, Mid piece, Principal piece, End piece" "Basal body, Cytosol" "HPA042204: , HPA043618: " "unprognostic (3.02e-2)" "unprognostic (4.19e-2)" "potential prognostic favorable (2.24e-4)" "unprognostic (3.01e-2)" "potential prognostic unfavorable (6.49e-5)" "unprognostic (2.53e-1)" "unprognostic (2.31e-1)" "unprognostic (9.39e-2)" "unprognostic (1.55e-1)" "unprognostic (2.30e-1)" "unprognostic (2.47e-3)" "unprognostic (7.85e-2)" "unprognostic (7.80e-3)" "unprognostic (1.22e-1)" "unprognostic (1.77e-1)" "unprognostic (3.87e-2)" CFAP46 "bA288G11.4, bA288G11.5, bB137A17.2, bB137A17.3, C10orf123, C10orf124, C10orf92, C10orf93, DKFZp434A1721, FLJ25954, TTC40" ENSG00000171811 "Cilia and flagella associated protein 46" Q8IYW2 10 132808392-132942823 "Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 29.3;testis: 39.9" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 181.4;Cone photoreceptor cells: 111.8;Endometrial ciliated cells: 290.2;Ependymal cells: 592.2;Epididymal efferent duct ciliated cells: 261.9;Fallopian tube ciliated cells: 249.6;Respiratory ciliated cells: 430.3" "Cell type enriched" "Detected in many" 4 "ependymal cell: 519.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA037786, HPA038034, HPA038867, HPA038868" Uncertain Approved "Mid piece,Principal piece,Annulus" NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 17: Choroid plexus - Cilium" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 34: Ciliated cells - Cilia assembly & function" "Mid piece, Principal piece, Annulus" "HPA037786: , HPA038034: , HPA038867: , HPA038868: " "unprognostic (7.61e-2)" "unprognostic (1.25e-2)" "unprognostic (2.17e-2)" "unprognostic (3.97e-3)" "unprognostic (1.67e-1)" "unprognostic (4.76e-2)" "unprognostic (1.56e-2)" "unprognostic (3.79e-3)" "unprognostic (2.92e-1)" CFAP47 "CHDC2, CXorf22, CXorf30, CXorf59, FLJ36601, MGC34831, RP13-11B7.1" ENSG00000165164 "Cilia and flagella associated protein 47" Q6ZTR5 X 35919734-36385317 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 4.4;pituitary gland: 1.7;retina: 1.4" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 336.3;Endometrial ciliated cells: 854.0;Ependymal cells: 1694.7;Epididymal efferent duct ciliated cells: 322.3;Fallopian tube ciliated cells: 667.0;Gonadotrophs: 204.0;Lactotrophs: 294.8;Respiratory ciliated cells: 917.7;Somatotrophs: 685.9;Thyrotrophs: 273.2" "Cell type enriched" "Detected in many" 5 "ependymal cell: 1823.8" "Cancer enhanced" "Detected in single" "Uterine Corpus Endometrial Carcinoma (TCGA): 1.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Skin - Outer root sheath cells, Testis - Early spermatids" "HPA044633, HPA054859" Uncertain NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 15: Kidney cancer - Membrane components" "Cluster 34: Ciliated cells - Cilia assembly & function" 1 "HPA044633: , HPA054859: " "unprognostic (2.39e-1)" "unprognostic (1.17e-2)" CFAP52 "FLJ37528, WDR16, WDRPUH" ENSG00000166596 "Cilia and flagella associated protein 52" Q8N1V2 17 9576627-9643447 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Heterotaxy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 37.4;fallopian tube: 54.4" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 118.5;Endometrial ciliated cells: 225.8;Ependymal cells: 555.1;Epididymal efferent duct ciliated cells: 250.1;Fallopian tube ciliated cells: 370.3;Late primary spermatocytes: 88.6;Respiratory ciliated cells: 504.6" "Cell type enriched" "Detected in many" 5 "ependymal cell: 591.8" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 4.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA023247 Enhanced Approved "Microtubules,Primary cilium,Centriolar satellite,Basal body" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 5: Rhabdoid - Unknown function" "Cluster 34: Ciliated cells - Cilia assembly & function" Microtubules "Primary cilium, Centriolar satellite, Basal body" "HPA023247: " "unprognostic (2.24e-2)" "unprognostic (2.72e-1)" "unprognostic (4.26e-2)" "unprognostic (1.84e-2)" "unprognostic (2.50e-2)" "unprognostic (2.76e-1)" "unprognostic (2.19e-1)" "unprognostic (3.21e-1)" "unprognostic (1.47e-1)" "unprognostic (2.21e-3)" "unprognostic (3.19e-1)" "unprognostic (4.86e-2)" "unprognostic (1.49e-2)" CFAP53 "CCDC11, FLJ32743" ENSG00000172361 "Cilia and flagella associated protein 53" Q96M91 18 50227193-50266495 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Differentiation, Spermatogenesis" "Developmental protein" "Ciliopathy, Disease variant, Heterotaxy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "choroid plexus: 19.4;fallopian tube: 26.8;testis: 76.5" "Group enriched" "Detected in many" 4 "Early spermatids: 699.4;Endometrial ciliated cells: 414.7;Epididymal efferent duct ciliated cells: 409.2;Fallopian tube ciliated cells: 446.2;Late primary spermatocytes: 1365.9;Late spermatids: 741.6;Respiratory ciliated cells: 538.9" "Group enriched" "Detected in all" 7 "choroid plexus epithelial cell: 50.0;ependymal cell: 181.9" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 8.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Testis - Early spermatids" HPA066142 Enhanced Approved "Nucleoplasm,Nuclear membrane,Basal body,Cytosol" NA No "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 107: Ciliated cells - Cilia assembly & function" 23 "Basal body, Cytosol" "Nucleoplasm, Nuclear membrane" "HPA066142: " "unprognostic (1.31e-1)" "unprognostic (1.31e-1)" "unprognostic (2.98e-1)" "unprognostic (2.83e-2)" "unprognostic (1.32e-1)" "unprognostic (3.85e-2)" "unprognostic (1.07e-2)" "potential prognostic favorable (3.22e-4)" "potential prognostic favorable (2.33e-6)" "unprognostic (7.68e-2)" "unprognostic (3.47e-1)" "unprognostic (3.54e-2)" "unprognostic (4.56e-3)" "unprognostic (3.43e-2)" "unprognostic (1.02e-1)" "unprognostic (8.08e-2)" "unprognostic (1.01e-1)" "unprognostic (4.72e-2)" "unprognostic (2.97e-2)" "unprognostic (3.23e-2)" CFAP54 "C12orf55, C12orf63, FLJ31514, FLJ44112" ENSG00000188596 "Cilia and flagella associated protein 54" Q96N23 12 96489571-96875555 "Essential proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation, Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 6.5;retina: 5.6" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 1724.1;Endometrial ciliated cells: 604.5;Ependymal cells: 3174.7;Epididymal efferent duct ciliated cells: 438.2;Fallopian tube ciliated cells: 695.9;Respiratory ciliated cells: 1426.3" "Group enriched" "Detected in all" 13 "choroid plexus epithelial cell: 1391.7;ependymal cell: 3403.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Minor Salivary Gland - Plasma cells, Stomach - Plasma cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA039897 Enhanced Approved "Microtubules,Cytokinetic bridge,Primary cilium,Basal body,Cytosol" Yes NA "Cluster 20: Non-specific - DNA binding" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 56: Non-specific - Sensory perception" "Cluster 34: Ciliated cells - Cilia assembly & function" "Microtubules, Cytokinetic bridge, Primary cilium" "Basal body, Cytosol" "HPA039897: " "unprognostic (1.80e-1)" "unprognostic (3.02e-2)" "unprognostic (1.77e-1)" "unprognostic (2.89e-3)" "unprognostic (5.42e-3)" "unprognostic (2.04e-1)" "unprognostic (1.75e-1)" "unprognostic (4.62e-2)" "potential prognostic unfavorable (3.95e-4)" "unprognostic (1.72e-2)" "unprognostic (3.51e-3)" "unprognostic (1.45e-1)" "unprognostic (2.70e-2)" "unprognostic (5.23e-2)" "unprognostic (1.74e-1)" "unprognostic (3.59e-2)" "unprognostic (4.53e-3)" "unprognostic (2.64e-1)" "unprognostic (6.34e-3)" "unprognostic (4.84e-2)" "unprognostic (6.42e-3)" "unprognostic (3.95e-2)" "unprognostic (7.91e-2)" "unprognostic (3.29e-3)" "unprognostic (2.51e-2)" "unprognostic (1.89e-1)" "unprognostic (3.66e-1)" "unprognostic (4.30e-2)" "unprognostic (2.32e-1)" CFAP57 "FLJ32000, WDR65" ENSG00000243710 "Cilia and flagella associated protein 57" Q96MR6 1 43172330-43254358 "Predicted intracellular proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "choroid plexus: 13.2;fallopian tube: 22.0;testis: 14.8" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 47.6;Endometrial ciliated cells: 118.3;Ependymal cells: 114.6;Epididymal efferent duct ciliated cells: 86.9;Fallopian tube ciliated cells: 188.0;Late primary spermatocytes: 75.3;Late spermatids: 40.6;Respiratory ciliated cells: 232.8" "Group enriched" "Detected in many" 6 "choroid plexus epithelial cell: 42.1;ependymal cell: 126.2" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 3.9" "Region enhanced" "Detected in all" "choroid plexus: 23.2" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.2" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in some" "Adrenocortical cancer: 4.1;lymphoma: 3.7" "Liver - Hepatocytes, Lung - Respiratory ciliated cells, Skin - Inner root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA002736, HPA028623, HPA028629" Enhanced Supported "Primary cilium,Cytosol" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 59: Leukemia - T-cell receptor" "Cluster 107: Ciliated cells - Cilia assembly & function" "Primary cilium, Cytosol" "HPA002736: , HPA028623: , HPA028629: " "unprognostic (4.05e-2)" "unprognostic (5.44e-2)" "unprognostic (1.67e-2)" "unprognostic (6.75e-3)" "unprognostic (2.22e-3)" "unprognostic (5.19e-2)" "unprognostic (5.22e-2)" "unprognostic (2.14e-1)" "unprognostic (1.91e-1)" "unprognostic (1.01e-2)" "unprognostic (5.67e-3)" CFAP58 "bA554P13.1, C10orf80, CCDC147, FLJ35908" ENSG00000120051 "Cilia and flagella associated protein 58" Q5T655 10 104353833-104455102 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 7.9;testis: 12.8" "Cell type enhanced" "Detected in many" "Early spermatids: 46.5;Endometrial ciliated cells: 52.2;Ependymal cells: 207.0;Epididymal efferent duct ciliated cells: 60.9;Fallopian tube ciliated cells: 132.2;Late primary spermatocytes: 107.6;Late spermatids: 77.6;Myonuclei: 35.8;Neutrophils: 50.5;Respiratory ciliated cells: 171.4" "Cell type enriched" "Detected in many" 15 "ependymal cell: 221.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 6 "neutrophil: 2.1" "Lineage enriched" "Detected in single" 21 "granulocytes: 2.1" "Low cancer specificity" "Detected in some" "Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Region enhanced" "Detected in single" "midbrain: 2.6" "HPA036555, HPA071938" Approved Supported "Calyx,Principal piece" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 34: Ciliated cells - Cilia assembly & function" 5 "Principal piece" Calyx "HPA036555: , HPA071938: " "unprognostic (2.38e-1)" CFAP61 "C20orf26, CaM-IP3, dJ1002M8.3, DKFZP434K156" ENSG00000089101 "Cilia and flagella associated protein 61" Q8NHU2 20 20052514-20360703 "Predicted intracellular proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 11.4;heart muscle: 11.6;skeletal muscle: 26.0;testis: 14.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 286.5;Choroid plexus epithelial cells: 315.0;Early spermatids: 143.2;Endometrial ciliated cells: 199.6;Ependymal cells: 600.0;Epididymal efferent duct ciliated cells: 149.4;Fallopian tube ciliated cells: 198.1;Late spermatids: 215.1;Myonuclei: 226.9;Respiratory ciliated cells: 476.7;Somatotrophs: 242.4;Thymic myoid cells: 477.2;Thyrotrophs: 207.4" "Group enriched" "Detected in all" 4 "choroid plexus epithelial cell: 246.0;ependymal cell: 616.6" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 3.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 2.8;skin cancer: 5.0" "Adrenal gland - Adrenal medulla cells, Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA009079 Approved Approved "Nucleoplasm,Cytosol,Principal piece" NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 17: Choroid plexus - Cilium" "Cluster 11: Neuronal - Sensory perception" "Cluster 34: Ciliated cells - Cilia assembly & function" "Cytosol, Principal piece" Nucleoplasm "HPA009079: " "unprognostic (7.26e-2)" "unprognostic (3.92e-2)" "unprognostic (1.85e-1)" "unprognostic (9.05e-2)" "unprognostic (3.07e-1)" "unprognostic (4.55e-1)" "unprognostic (6.90e-2)" "unprognostic (1.45e-1)" CFAP65 "CCDC108, DKFZp434O0527, MGC35338" ENSG00000181378 "Cilia and flagella associated protein 65" Q6ZU64 2 219002846-219041527 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 8.9;fallopian tube: 24.2;retina: 8.5;testis: 8.8" "Cell type enhanced" "Detected in many" "Early spermatids: 270.4;Endometrial ciliated cells: 76.0;Ependymal cells: 201.5;Epididymal efferent duct ciliated cells: 88.6;Fallopian tube ciliated cells: 128.4;Late primary spermatocytes: 167.1;Late spermatids: 308.7;Neuroendocrine cells: 54.8;Respiratory ciliated cells: 182.4" "Cell type enriched" "Detected in many" 7 "ependymal cell: 230.1" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 2.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "midbrain: 10.4" HPA055156 Uncertain "Intracellular and membrane" Other NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" "HPA055156: " "unprognostic (7.65e-3)" "unprognostic (1.32e-2)" "unprognostic (2.57e-3)" "unprognostic (1.71e-1)" CFAP69 "C7orf63, FAP69, FLJ21062" ENSG00000105792 "Cilia and flagella associated protein 69" A5D8W1 7 90245174-90311063 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Olfaction, Sensory transduction, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 50.5" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 287.0;Endometrial ciliated cells: 369.8;Ependymal cells: 506.6;Epididymal efferent duct ciliated cells: 288.3;Fallopian tube ciliated cells: 338.3;Prostatic glandular cells: 537.7;Respiratory ciliated cells: 394.9" "Group enriched" "Detected in all" 5 "choroid plexus epithelial cell: 286.4;ependymal cell: 559.0" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 22.6" "Region enhanced" "Detected in all" "choroid plexus: 41.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 13.0" "Prostate - Prostate glandular cells, Spleen - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062883 Uncertain NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 60: Prostate cancer - Unknown function" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" "HPA062883: " "unprognostic (2.24e-1)" "unprognostic (1.37e-2)" "unprognostic (1.80e-2)" "unprognostic (1.38e-1)" "unprognostic (5.68e-2)" "unprognostic (4.50e-2)" "unprognostic (1.29e-1)" "unprognostic (1.48e-2)" "unprognostic (8.18e-3)" "unprognostic (6.15e-2)" "unprognostic (4.65e-3)" "unprognostic (4.92e-2)" "unprognostic (2.18e-2)" "unprognostic (1.12e-1)" "unprognostic (1.01e-2)" "unprognostic (3.67e-1)" "unprognostic (2.08e-1)" "unprognostic (5.85e-2)" "unprognostic (5.74e-3)" "unprognostic (5.23e-2)" "unprognostic (1.38e-1)" "unprognostic (1.00e-2)" "unprognostic (5.00e-2)" "unprognostic (3.20e-2)" "unprognostic (2.81e-2)" "unprognostic (1.30e-2)" "unprognostic (1.14e-2)" "unprognostic (1.16e-1)" CFAP70 "FLJ25765, TTC18" ENSG00000156042 "Cilia and flagella associated protein 70" 10 73253762-73358864 "Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 56.9" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 484.7;Endometrial ciliated cells: 408.0;Ependymal cells: 1125.6;Epididymal efferent duct ciliated cells: 248.0;Fallopian tube ciliated cells: 359.7;Respiratory ciliated cells: 673.2" "Group enriched" "Detected in all" 4 "choroid plexus epithelial cell: 423.7;ependymal cell: 1161.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 3.6" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA037582, HPA070304" Enhanced Approved "Centrosome,Basal body,Cytosol,Mid piece,Principal piece,End piece" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" 1 "Centrosome, Basal body, Cytosol" "Mid piece, Principal piece, End piece" "HPA037582: , HPA070304: " "unprognostic (9.47e-3)" "unprognostic (1.51e-1)" "unprognostic (2.64e-2)" "unprognostic (1.94e-1)" "unprognostic (2.09e-1)" "unprognostic (1.52e-1)" "unprognostic (8.70e-3)" "unprognostic (1.20e-3)" "unprognostic (2.81e-2)" "unprognostic (2.61e-1)" "unprognostic (2.18e-1)" "unprognostic (3.85e-1)" "unprognostic (1.46e-2)" "unprognostic (2.07e-2)" "unprognostic (7.95e-3)" "unprognostic (5.88e-3)" "unprognostic (2.46e-3)" "unprognostic (1.36e-1)" "unprognostic (2.91e-2)" "unprognostic (1.10e-1)" CFAP73 "CCDC42B, MIA2" ENSG00000186710 "Cilia and flagella associated protein 73" A6NFT4 12 113149724-113159276 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 29.6;fallopian tube: 33.5" "Group enriched" "Detected in some" 6 "Endometrial ciliated cells: 208.2;Ependymal cells: 503.3;Epididymal efferent duct ciliated cells: 369.8;Fallopian tube ciliated cells: 477.0;Respiratory ciliated cells: 555.9" "Cell type enriched" "Detected in many" 8 "ependymal cell: 549.1" "Cancer enriched" "Detected in many" 5 "Uterine Corpus Endometrial Carcinoma (TCGA): 20.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 4.1" "Breast - Breast glandular cells (progenitors), Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA048539 Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Vesicles" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 6: Leukemia - Signal transduction" "Cluster 34: Ciliated cells - Cilia assembly & function" "Nucleoli fibrillar center" "Nucleoplasm, Vesicles" "HPA048539: " "potential prognostic favorable (7.65e-5)" "unprognostic (1.06e-1)" "unprognostic (2.32e-2)" "unprognostic (4.40e-3)" "unprognostic (2.19e-1)" "unprognostic (1.86e-1)" "unprognostic (2.26e-2)" "unprognostic (1.09e-1)" "unprognostic (7.71e-3)" "unprognostic (8.96e-2)" "unprognostic (1.57e-2)" "unprognostic (2.73e-2)" "unprognostic (1.86e-1)" "potential prognostic favorable (3.29e-5)" "unprognostic (5.27e-2)" "unprognostic (4.65e-2)" CFAP74 "C1orf222, FLJ45476, KIAA1751" ENSG00000142609 "Cilia and flagella associated protein 74" Q9C0B2 1 1921951-2003837 "Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 3.6;fallopian tube: 6.5;testis: 4.8" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 72.6;Differentiating spermatogonia: 26.5;Endometrial ciliated cells: 75.5;Ependymal cells: 112.0;Epididymal efferent duct ciliated cells: 59.6;Fallopian tube ciliated cells: 94.4;Late primary spermatocytes: 26.9;Late spermatids: 35.0;Microglia: 35.7;Respiratory ciliated cells: 185.6" "Cell type enhanced" "Detected in many" "ependymal cell: 106.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA028521, HPA029274, HPA030240" Enhanced NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 56: Non-specific - Sensory perception" "Cluster 107: Ciliated cells - Cilia assembly & function" 1 "HPA028521: , HPA029274: , HPA030240: " "unprognostic (3.23e-1)" "unprognostic (1.16e-1)" "unprognostic (8.97e-3)" "potential prognostic favorable (5.17e-4)" "unprognostic (2.39e-2)" "unprognostic (6.01e-2)" "unprognostic (4.46e-2)" "unprognostic (3.23e-1)" CFAP77 "C9orf171, FLJ46082" ENSG00000188523 "Cilia and flagella associated protein 77" Q6ZQR2 9 132410043-132573319 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "choroid plexus: 21.6;fallopian tube: 27.9;testis: 17.7" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 124.1;Early spermatids: 126.6;Endometrial ciliated cells: 202.6;Ependymal cells: 210.7;Epididymal efferent duct ciliated cells: 155.7;Erythrocyte progenitors: 67.0;Fallopian tube ciliated cells: 222.1;Late primary spermatocytes: 156.3;Late spermatids: 94.6;Oocytes: 198.0;Respiratory ciliated cells: 350.7" "Group enriched" "Detected in many" 9 "choroid plexus epithelial cell: 96.7;ependymal cell: 233.6" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 8.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "midbrain: 23.3" "HPA021329, HPA061069" Enhanced NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" 2 "HPA021329: , HPA061069: " "unprognostic (4.72e-2)" "unprognostic (2.54e-3)" "unprognostic (4.97e-2)" "unprognostic (2.15e-1)" "unprognostic (2.94e-2)" "unprognostic (2.26e-2)" "unprognostic (3.22e-2)" CFAP91 "AAT-1, AAT1, AAT1alpha, C3orf15, CaM-IP2, MAATS1, SPATA26" ENSG00000183833 "Cilia and flagella associated protein 91" Q7Z4T9 3 119703022-119767102 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 15.4;fallopian tube: 13.3" "Group enriched" "Detected in some" 5 "Early spermatids: 324.2;Late primary spermatocytes: 243.8" "Group enriched" "Detected in some" 5 "choroid plexus epithelial cell: 2.3;ependymal cell: 4.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose visceral - Mesothelial cells, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA074084 Supported NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 3 "HPA074084: " "unprognostic (3.42e-2)" "unprognostic (1.93e-1)" "unprognostic (3.83e-3)" "potential prognostic favorable (3.37e-8)" "unprognostic (8.40e-2)" "unprognostic (1.50e-1)" "unprognostic (3.53e-2)" "unprognostic (9.95e-2)" "unprognostic (1.76e-1)" "unprognostic (1.75e-2)" "unprognostic (3.07e-2)" "unprognostic (6.91e-2)" "unprognostic (1.73e-2)" "unprognostic (2.01e-2)" "unprognostic (1.48e-2)" CFAP92 "FAP92, FLJ43738, KIAA1257" ENSG00000114656 "Cilia and flagella associated protein 92 (putative)" Q9ULG3 3 128909866-129002690 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 23.9" "Cell type enhanced" "Detected in many" "Early spermatids: 209.0;Ependymal cells: 147.7;Epicardial cells: 145.5;Late primary spermatocytes: 204.5;Late spermatids: 320.6;Oocytes: 87.5;Respiratory ciliated cells: 90.2" "Cell type enhanced" "Detected in all" "ependymal cell: 164.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 12 "neutrophil: 34.1" "Lineage enriched" "Detected in single" 46 "granulocytes: 34.1" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA042811, HPA048445" Uncertain NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 32: Non-specific - Cell proliferation" "Cluster 34: Ciliated cells - Cilia assembly & function" "HPA042811: , HPA048445: " "unprognostic (1.17e-1)" "unprognostic (5.43e-2)" "unprognostic (1.06e-1)" "unprognostic (1.26e-1)" "potential prognostic unfavorable (1.50e-4)" "unprognostic (2.77e-2)" "unprognostic (2.60e-2)" "unprognostic (2.32e-1)" "unprognostic (6.12e-2)" "unprognostic (1.49e-2)" "unprognostic (1.26e-2)" "unprognostic (6.29e-2)" "unprognostic (1.20e-2)" "unprognostic (1.61e-1)" "unprognostic (1.13e-1)" "unprognostic (2.92e-1)" "unprognostic (1.01e-2)" "unprognostic (1.36e-1)" "unprognostic (1.70e-2)" "unprognostic (2.20e-1)" "unprognostic (1.73e-1)" "unprognostic (3.49e-2)" "unprognostic (1.50e-1)" CFAP95 C9orf135 ENSG00000204711 "Cilia and flagella associated protein 95" Q5VTT2 9 69820817-69906227 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 27.5;fallopian tube: 34.6;testis: 15.3" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 98.3;Cone photoreceptor cells: 72.5;Early spermatids: 137.3;Endometrial ciliated cells: 268.0;Epididymal efferent duct ciliated cells: 251.0;Fallopian tube ciliated cells: 535.1;Lactotrophs: 106.4;Late primary spermatocytes: 236.3;Respiratory ciliated cells: 505.2;Thyrotrophs: 89.0" "Group enriched" "Detected in many" 5 "choroid plexus epithelial cell: 97.8;ependymal cell: 80.7" "Cancer enhanced" "Detected in some" "Lung Adenocarcinoma (TCGA): 3.4;Testicular Germ Cell Tumor (TCGA): 8.1" "Region enhanced" "Detected in many" "choroid plexus: 13.8" "Group enriched" "Detected in some" 5 "naive CD4 T-cell: 1.2;naive CD8 T-cell: 1.7;T-reg: 1.5" "Lineage enriched" "Detected in single" 17 "T-cells: 1.7" "Cancer enriched" "Detected in some" 4 "testis cancer: 4.1" "Lung - Respiratory ciliated cells, Pituitary gland - Lactotropes, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021261, HPA021325" Uncertain Approved "Mid piece,Principal piece" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 15: Kidney cancer - Membrane components" "Cluster 107: Ciliated cells - Cilia assembly & function" "Mid piece, Principal piece" "HPA021261: , HPA021325: " "unprognostic (5.29e-2)" "unprognostic (2.63e-2)" "unprognostic (3.89e-1)" "unprognostic (7.01e-2)" "unprognostic (1.63e-2)" "unprognostic (3.61e-1)" "unprognostic (3.81e-1)" CFAP97 "DKFZp434F1728, hmw, KIAA1430" ENSG00000164323 "Cilia and flagella associated protein 97" Q9P2B7 4 185159665-185209504 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 244.4;Late primary spermatocytes: 462.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049446, HPA053335" Uncertain Approved "Nucleoli fibrillar center,Primary cilium,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 17: Non-specific - RNA processing" 10 "Nucleoli fibrillar center" "Primary cilium, Cytosol" "HPA049446: , HPA053335: " "unprognostic (3.91e-2)" "unprognostic (2.08e-1)" "unprognostic (6.80e-3)" "unprognostic (2.65e-2)" "unprognostic (2.35e-1)" "unprognostic (3.13e-1)" "unprognostic (6.69e-2)" "unprognostic (4.46e-2)" "potential prognostic unfavorable (6.76e-4)" "validated prognostic favorable (2.60e-7)" "validated prognostic favorable (4.13e-4)" "unprognostic (2.07e-1)" "unprognostic (3.63e-3)" "unprognostic (3.06e-2)" "unprognostic (3.36e-2)" "unprognostic (1.21e-1)" "unprognostic (1.90e-1)" "unprognostic (1.99e-2)" "unprognostic (2.24e-2)" "unprognostic (1.84e-2)" "unprognostic (5.28e-2)" "unprognostic (3.81e-1)" "unprognostic (3.32e-2)" "unprognostic (9.39e-2)" "unprognostic (5.07e-2)" "unprognostic (4.32e-2)" "unprognostic (4.14e-1)" "unprognostic (2.67e-2)" "unprognostic (2.04e-2)" CFAP97D1 C17orf105 ENSG00000231256 "CFAP97 domain containing 1" B2RV13 17 43780435-43787620 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 25 "testis: 12.4" "Group enriched" "Detected in some" 7 "Early spermatids: 1825.3;Late spermatids: 2392.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA023071, HPA053028" Approved Approved "Plasma membrane" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 48: Non-specific - Mixed function" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 1 "Plasma membrane" "HPA023071: , HPA053028: " "unprognostic (3.28e-1)" "unprognostic (6.20e-2)" "unprognostic (1.64e-1)" CFAP97D2 ENSG00000283361 "CFAP97 domain containing 2" A0A1B0GU71 13 114154691-114223085 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "choroid plexus: 7.1;fallopian tube: 18.4;pancreas: 6.0" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 33.9;Early primary spermatocytes: 79.8;Endometrial ciliated cells: 38.8;Ependymal cells: 205.4;Epididymal efferent duct ciliated cells: 37.4;Fallopian tube ciliated cells: 138.0;Pancreatic acinar cells: 44.2;Respiratory ciliated cells: 96.6" "Cell type enriched" "Detected in many" 8 "ependymal cell: 205.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 13 "naive CD8 T-cell: 4.0" "Lineage enriched" "Detected in single" 40 "T-cells: 4.0" "Not detected" "Not detected" "Lung - Respiratory ciliated cells" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 59: Leukemia - T-cell receptor" "Cluster 34: Ciliated cells - Cilia assembly & function" CFAP99 ENSG00000206113 "Cilia and flagella associated protein 99" D6REC4 4 2418974-2462942 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "testis: 15.0" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 24.3;Cone photoreceptor cells: 16.6;Endometrial ciliated cells: 33.3;Ependymal cells: 53.8;Epididymal efferent duct ciliated cells: 25.2;Fallopian tube ciliated cells: 33.7;Late primary spermatocytes: 45.7;Late spermatids: 27.7;Respiratory ciliated cells: 67.4;Rod photoreceptor cells: 16.8" "Group enriched" "Detected in many" 8 "choroid plexus epithelial cell: 18.0;ependymal cell: 56.9" "Cancer enhanced" "Detected in single" "Uterine Corpus Endometrial Carcinoma (TCGA): 1.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA071642 Approved "Microtubules,Cytokinetic bridge,Mitotic spindle,Mid piece,Principal piece,End piece" Yes NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 34: Ciliated cells - Cilia assembly & function" "Microtubules, Mid piece, Principal piece, End piece" "Cytokinetic bridge, Mitotic spindle" "HPA071642: " "unprognostic (2.45e-1)" CFB "BF, BFD, H2-Bf" ENSG00000243649 "Complement factor B" P00751 6 31945650-31952086 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Complement alternate pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 19 "liver: 2370.8" "Cell type enhanced" "Detected in some" "Cholangiocytes: 3.3;Endometrial secretory cells: 9.1;Epicardial cells: 34.1;Mesothelial cells: 9.3;Prostatic club cells: 5.2;Renal collecting duct principal cells: 3.5" "Cell type enhanced" "Detected in some" "endothelial cell: 5.7;vascular associated smooth muscle cell: 1.7" "Cancer enriched" "Detected in all" 7 "Liver Hepatocellular Carcinoma (TCGA): 1490.2" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "head and neck cancer: 34.6" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Mesothelial cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Spleen - Fibroblasts_1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA000951, HPA001817, HPA001832, CAB016381" Supported Approved "Endoplasmic reticulum,Vesicles,Cell Junctions" "Secreted to blood" Immunity NA NA 879000000 89000000000 "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 5 "Endoplasmic reticulum, Vesicles" "Cell Junctions" "CAB016381: , HPA000951: , HPA001817: , HPA001832: " "unprognostic (4.10e-2)" "unprognostic (4.75e-3)" "unprognostic (3.23e-1)" "unprognostic (5.06e-2)" "unprognostic (3.92e-1)" "unprognostic (2.87e-1)" "unprognostic (3.73e-2)" "unprognostic (1.40e-2)" "unprognostic (1.02e-1)" "unprognostic (1.24e-1)" "potential prognostic unfavorable (2.40e-5)" "unprognostic (8.00e-2)" "unprognostic (4.95e-3)" "unprognostic (9.65e-3)" "potential prognostic favorable (1.37e-7)" "unprognostic (2.35e-1)" "unprognostic (1.46e-1)" "unprognostic (1.25e-1)" "unprognostic (1.13e-2)" "unprognostic (2.42e-1)" "unprognostic (1.34e-1)" "unprognostic (1.35e-2)" "unprognostic (2.63e-2)" "unprognostic (1.34e-1)" "unprognostic (3.57e-2)" "unprognostic (7.08e-2)" "unprognostic (2.72e-1)" "unprognostic (1.87e-1)" "unprognostic (1.17e-2)" "unprognostic (2.91e-3)" "unprognostic (2.76e-2)" CFC1 "CRYPTIC, HTX2" ENSG00000136698 "Cripto, FRL-1, cryptic family 1" P0CG37 2 130592165-130599575 "Disease related genes, Human disease related genes, Predicted secreted proteins" Gastrulation "Developmental protein" "Disease variant, Heterotaxy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 22.6;pancreas: 17.8;pituitary gland: 35.5" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 6.7;Brain inhibitory neurons: 5.6;Corticotrophs: 11.4;Neuroendocrine cells: 33.0;Other brain neurons: 30.8;Pancreatic islet cells: 55.6;Retinal bipolar cells: 10.8;Somatotrophs: 12.9" "Cell type enhanced" "Detected in many" "lower rhombic lip: 14.9;mammillary body: 18.8" "Cancer enriched" "Detected in some" 6 "Pancreatic Adenocarcinoma (TCGA): 49.6" "Region enhanced" "Detected in many" "hypothalamus: 55.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "prostate cancer: 13.7;testis cancer: 3.6" "Adipose visceral - Mesothelial cells, Pancreas - Alpha cells, Pancreas - Beta cells, Prostate - Prostate glandular cells, Stomach - Gastric enteroendocrine cells" HPA041773 Uncertain "Secreted - unknown location" "Developmental protein" NA NA "Cluster 70: Non-specific - Protein processing" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 79 "HPA041773: " "unprognostic (1.64e-1)" "unprognostic (2.76e-3)" "unprognostic (7.52e-2)" "unprognostic (2.11e-3)" "unprognostic (5.11e-1)" CFC1B ENSG00000152093 "Cripto, FRL-1, cryptic family 1B" P0CG36 2 130521197-130528604 "Predicted secreted proteins" Gastrulation "Developmental protein" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "pituitary gland: 1.2" "Cell type enhanced" "Detected in single" "Retinal bipolar cells: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA041773 Approved "Secreted - unknown location" "Developmental protein" NA NA "Cluster 70: Non-specific - Protein processing" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "HPA041773: " CFD "ADN, DF, PFD" ENSG00000197766 "Complement factor D" P00746 19 859453-867884 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Complement alternate pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 1421.6" "Group enriched" "Detected in many" 7 "Decidual stromal cells: 2523.6;Fibroblasts: 2406.7;Leydig cells: 1762.2" "Group enriched" "Detected in many" 4 "central nervous system macrophage: 24.1;leukocyte: 12.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 1712.8" "Lineage enriched" "Detected in all" 6 "granulocytes: 1712.8" "Cancer enhanced" "Detected in all" "Leukemia: 84.8" "Adipose subcutaneous - Mast cells, Colon - Fibroblasts, Kidney - Fibroblasts, Minor Salivary Gland - Fibroblasts, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblasts_2, Stomach - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted to blood" Immunity NA NA 732000000 1500000000 "Cluster 35: Neutrophils - Protein binding" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 48: Non-specific - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 108: Fibroblasts - ECM organization" "unprognostic (5.02e-2)" "unprognostic (7.59e-2)" "unprognostic (7.88e-2)" "unprognostic (9.80e-2)" "unprognostic (1.33e-1)" "unprognostic (1.88e-2)" "unprognostic (1.14e-2)" "unprognostic (2.02e-2)" "unprognostic (1.71e-1)" "unprognostic (2.64e-2)" "unprognostic (1.62e-2)" "unprognostic (1.80e-1)" "unprognostic (1.05e-2)" "unprognostic (8.82e-3)" "unprognostic (1.47e-2)" "unprognostic (2.77e-1)" "unprognostic (5.79e-2)" "unprognostic (9.28e-3)" "unprognostic (6.55e-2)" "unprognostic (7.42e-2)" "unprognostic (5.86e-2)" "unprognostic (1.61e-2)" "unprognostic (2.32e-1)" "unprognostic (2.33e-1)" "unprognostic (1.47e-1)" "unprognostic (1.67e-1)" "unprognostic (1.16e-2)" "unprognostic (1.32e-1)" "unprognostic (9.75e-3)" "unprognostic (1.02e-2)" "unprognostic (2.71e-1)" CFDP1 "BCNT, CENP-29, CP27, p97, SWC5, Yeti" ENSG00000153774 "Craniofacial development protein 1" Q9UEE9 16 75293698-75433503 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Enterocytes: 597.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041316, HPA048242" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 65: Brain - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 18 Nucleoplasm Vesicles "HPA041316: , HPA048242: " "unprognostic (3.28e-1)" "unprognostic (3.80e-2)" "unprognostic (2.21e-2)" "unprognostic (4.74e-2)" "unprognostic (7.85e-2)" "unprognostic (1.08e-1)" "unprognostic (6.86e-2)" "unprognostic (9.03e-3)" "potential prognostic unfavorable (6.60e-5)" "unprognostic (3.35e-2)" "potential prognostic favorable (1.71e-5)" "unprognostic (1.75e-2)" "unprognostic (1.05e-1)" "unprognostic (1.43e-2)" "unprognostic (1.61e-3)" "unprognostic (2.75e-1)" "unprognostic (1.70e-2)" "unprognostic (7.32e-2)" "unprognostic (1.52e-1)" "unprognostic (2.78e-1)" "unprognostic (2.48e-2)" "unprognostic (1.14e-1)" "potential prognostic unfavorable (2.63e-7)" "unprognostic (4.36e-2)" "unprognostic (1.57e-2)" "unprognostic (4.05e-2)" "unprognostic (2.16e-2)" "unprognostic (5.99e-3)" "unprognostic (1.74e-1)" "unprognostic (7.71e-2)" "unprognostic (4.10e-2)" CFH "ARMD4, ARMS1, FHL1, HF, HF1, HF2, HUS" ENSG00000000971 "Complement factor H" P08603 1 196651754-196752476 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement alternate pathway, Host-virus interaction, Immunity, Innate immunity" "Age-related macular degeneration, Cancer-related genes, Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 1585.8" "Cell type enhanced" "Detected in many" "Fibroblasts: 82.4;Hepatic stellate cells: 51.6;Hepatocytes: 124.0;Leydig cells: 57.2;Ovarian stromal cells: 74.8;Papillary tip epithelial cells: 99.0;Pericytes: 36.5;Peritubular myoid cells: 42.9;Podocytes: 64.8" "Group enriched" "Detected in many" 7 "endothelial cell: 317.6;fibroblast: 269.5;pericyte: 401.5;vascular associated smooth muscle cell: 148.7" "Cancer enriched" "Detected in all" 8 "Liver Hepatocellular Carcinoma (TCGA): 549.3" "Region enhanced" "Detected in all" "choroid plexus: 43.6" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 17.6" "Lineage enriched" "Detected in single" 56 "T-cells: 17.6" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 59.2" "Adrenal gland - Fibroblasts, Heart muscle - Fibroblasts, Liver - Hepatocytes, Lung - Fibroblasts_2" "CAB016385, CAB016769, HPA038922, HPA049176, HPA053326" Supported Approved Vesicles "Secreted to blood" Immunity NA NA 396000000000 130000000000 "Cluster 1: T-cells - Unknown function" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 104: Brain endothelial cells - Blood brain barrier" 9 Vesicles "CAB016385: , CAB016769: , HPA038922: , HPA049176: , HPA053326: " "unprognostic (2.82e-1)" "unprognostic (2.43e-1)" "unprognostic (4.00e-1)" "unprognostic (1.02e-1)" "unprognostic (2.68e-1)" "unprognostic (1.49e-1)" "unprognostic (2.50e-3)" "potential prognostic unfavorable (4.94e-4)" "unprognostic (2.72e-1)" "unprognostic (2.64e-2)" "unprognostic (4.37e-3)" "unprognostic (2.61e-2)" "unprognostic (1.77e-1)" "unprognostic (9.04e-3)" "unprognostic (2.71e-3)" "unprognostic (1.75e-1)" "unprognostic (3.36e-2)" "unprognostic (2.15e-1)" "unprognostic (2.68e-2)" "unprognostic (5.99e-2)" "unprognostic (2.67e-2)" "unprognostic (4.27e-2)" "unprognostic (4.35e-1)" "unprognostic (1.78e-1)" "unprognostic (4.27e-2)" "unprognostic (1.16e-1)" "unprognostic (1.27e-2)" "unprognostic (1.50e-2)" "unprognostic (8.50e-3)" "unprognostic (2.08e-1)" "unprognostic (3.29e-2)" CFHR1 "CFHL, CFHL1, CFHL1P, CFHR1P, FHR1, H36-1, H36-2, HFL1, HFL2" ENSG00000244414 "Complement factor H related 1" Q03591 1 196819731-196837159 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 225 "liver: 1937.3" "Group enriched" "Detected in some" 5 "Granulosa cells: 50.3;Hepatocytes: 131.2" "Cell type enhanced" "Detected in single" "MGE interneuron: 1.2" "Cancer enriched" "Detected in some" 601 "Liver Hepatocellular Carcinoma (TCGA): 918.7" "Region enhanced" "Detected in single" "midbrain: 1.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Sarcoma: 3.3;thyroid cancer: 7.0" "Liver - Hepatocytes" "Not detected" "Not detected" "HPA038915, HPA038922, HPA040726" Supported Approved Vesicles "Secreted to blood" "Complement pathway" NA NA 75000000000 16000000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 7 Vesicles "HPA038915: , HPA038922: , HPA040726: " "unprognostic (8.31e-2)" "validated prognostic unfavorable (5.54e-4)" "validated prognostic unfavorable (9.07e-4)" "validated prognostic favorable (2.26e-5)" "validated prognostic favorable (1.68e-7)" "unprognostic (9.22e-2)" CFHR2 "CFHL2, FHR2, HFL3" ENSG00000080910 "Complement factor H related 2" P36980 1 196943738-196959622 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 2834 "liver: 1262.2" "Cell type enriched" "Detected in some" 144 "Hepatocytes: 1476.1" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 660 "Liver Hepatocellular Carcinoma (TCGA): 612.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes" "HPA038915, HPA040726, HPA049813" Supported "Secreted to blood" "Complement pathway" NA NA 40000000000 4300000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 7: Liver cancer - Metabolism" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 1 "HPA038915: , HPA040726: , HPA049813: " "unprognostic (1.01e-3)" "potential prognostic favorable (1.46e-4)" CFHR3 "CFHL3, DOWN16, FHR-3, FHR3, HLF4" ENSG00000116785 "Complement factor H related 3" Q02985 1 196774813-196795407 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 743 "liver: 366.8" "Cell type enhanced" "Detected in single" "Hepatocytes: 1.1" "Cell type enhanced" "Detected in some" "endothelial cell: 1.3;pericyte: 2.5" "Cancer enriched" "Detected in some" 52 "Liver Hepatocellular Carcinoma (TCGA): 74.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 2.6;thyroid cancer: 2.8" HPA077529 Approved Vesicles "Secreted to blood" "Complement pathway" NA NA 582000000 2600000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 9: Non-specific - Receptor signaling" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 2 Vesicles "HPA077529: " "unprognostic (1.63e-2)" "unprognostic (2.96e-1)" "unprognostic (2.90e-1)" "validated prognostic favorable (1.54e-5)" "validated prognostic favorable (1.25e-8)" "unprognostic (2.54e-1)" "unprognostic (8.16e-2)" "unprognostic (6.19e-2)" "unprognostic (1.93e-2)" CFHR4 "CFHL4, FHR-4, FHR4" ENSG00000134365 "Complement factor H related 4" Q92496 1 196888014-196918795 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 536 "liver: 95.0" "Cell type enriched" "Detected in some" 25 "Hepatocytes: 62.8" "Cell type enhanced" "Detected in some" "deep-layer near-projecting: 2.4;MGE interneuron: 1.9" "Cancer enriched" "Detected in single" 157 "Liver Hepatocellular Carcinoma (TCGA): 30.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes" "Secreted to blood" "Complement pathway" NA NA 28000000000 320000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" "validated prognostic favorable (3.05e-7)" "validated prognostic favorable (1.26e-5)" CFHR5 "CFHL5, FHR-5, FHR5" ENSG00000134389 "Complement factor H related 5" Q9BXR6 1 196975010-197009678 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1562 "liver: 156.2" "Cell type enriched" "Detected in some" 30 "Hepatocytes: 125.4" "Cell type enriched" "Detected in single" 4 "deep-layer near-projecting: 1.2" "Cancer enriched" "Detected in single" 283 "Liver Hepatocellular Carcinoma (TCGA): 71.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes" "HPA038915, HPA040726" Supported "Secreted to blood" "Complement pathway" NA NA 2550000000 1100000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 18: Liver cancer - Metabolism" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 15 "HPA038915: , HPA040726: " "unprognostic (9.73e-3)" "potential prognostic favorable (2.33e-5)" CFI "C3b-INA, FI, IF, KAF" ENSG00000205403 "Complement factor I" P05156 4 109731008-109802150 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Complement pathway, Host-virus interaction, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 917.6" "Cell type enhanced" "Detected in many" "Cholangiocytes: 15.7;Endometrial secretory cells: 20.7;Endometrial stromal cells: 15.7;Epididymal efferent duct absorptive cells: 12.7;Fallopian secretory cells: 12.7;Granulosa cells: 13.8;Hepatocytes: 50.1;Lymphatic endothelial cells: 12.7;Mesothelial cells: 20.5;Salivary duct cells: 13.3;Vascular endothelial cells: 11.4" "Cell type enriched" "Detected in some" 6 "endothelial cell: 68.4" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 220.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Colon - Endothelial cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Spleen - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA001143, CAB016777, HPA024061" Supported "Secreted to blood" "Complement pathway" NA NA 30300000000 19000000000 "Cluster 16: Liver & Kidney - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 104: Brain endothelial cells - Blood brain barrier" 6 "CAB016777: , HPA001143: , HPA024061: " "unprognostic (1.80e-1)" "unprognostic (7.81e-2)" "unprognostic (1.36e-1)" "unprognostic (2.08e-2)" "unprognostic (2.09e-1)" "unprognostic (2.13e-1)" "unprognostic (9.86e-3)" "unprognostic (1.34e-1)" "unprognostic (1.25e-1)" "unprognostic (2.25e-2)" "unprognostic (3.60e-3)" "potential prognostic favorable (1.43e-4)" "unprognostic (3.38e-1)" "unprognostic (1.31e-1)" "potential prognostic favorable (4.43e-5)" "unprognostic (4.34e-1)" "unprognostic (2.29e-1)" "unprognostic (6.92e-2)" "unprognostic (3.92e-2)" "unprognostic (4.57e-2)" "unprognostic (8.65e-2)" "unprognostic (1.35e-1)" "unprognostic (2.95e-1)" "unprognostic (3.13e-1)" "unprognostic (5.53e-2)" "unprognostic (4.21e-1)" "unprognostic (6.35e-3)" "unprognostic (4.84e-2)" "unprognostic (1.76e-1)" "unprognostic (1.24e-1)" "unprognostic (6.07e-2)" CFL1 CFL ENSG00000172757 "Cofilin 1" P23528 11 65823022-65862026 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Colonocytes: 2419.1;Esophageal apical cells: 2705.8;Extravillous trophoblasts: 3158.3;Hofbauer cells: 3412.1;Megakaryocytes: 2825.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033687, CAB037077, HPA053761, HPA077782" Approved Approved "Plasma membrane" NA NA 280000000 "Cluster 29: Non-specific - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 14: Neurons - Synaptic function" "Cluster 24: Non-specific - Unknown function" "Cluster 47: Platelets - Hemostasis" 75 "Plasma membrane" "CAB033687: , CAB037077: , HPA053761: , HPA077782: " "unprognostic (1.22e-2)" "unprognostic (1.38e-1)" "unprognostic (1.39e-1)" "potential prognostic unfavorable (9.34e-5)" "unprognostic (1.02e-1)" "unprognostic (3.63e-1)" "unprognostic (7.82e-2)" "unprognostic (4.24e-2)" "unprognostic (2.43e-3)" "unprognostic (5.65e-3)" "potential prognostic favorable (9.65e-4)" "unprognostic (1.96e-1)" "unprognostic (1.46e-1)" "potential prognostic unfavorable (4.83e-7)" "unprognostic (1.37e-3)" "validated prognostic unfavorable (3.55e-4)" "validated prognostic unfavorable (9.50e-8)" "unprognostic (1.95e-2)" "unprognostic (4.60e-2)" "unprognostic (1.68e-1)" "unprognostic (1.02e-1)" "unprognostic (1.53e-3)" "unprognostic (2.25e-1)" "unprognostic (1.56e-1)" "unprognostic (2.94e-1)" "unprognostic (2.16e-1)" "unprognostic (1.63e-1)" "unprognostic (8.43e-2)" "unprognostic (5.95e-2)" "unprognostic (3.98e-2)" "unprognostic (6.35e-2)" CFL2 NEM7 ENSG00000165410 "Cofilin 2" Q9Y281 14 34709113-34714823 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Disease variant, Nemaline myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "heart muscle: 348.8;skeletal muscle: 674.8;tongue: 640.8" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 194.5;Epididymal clear cells: 175.6;Smooth muscle cells: 373.7;Thymic myoid cells: 274.6" "Cell type enhanced" "Detected in all" "oligodendrocyte: 126.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal cortex cells, Colon - Smooth muscle cells, Liver - Hepatocytes, Minor Salivary Gland - Endothelial cells, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037078, HPA045599, HPA077782" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 39000000 "Cluster 24: Non-specific - Transcription" "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 62: Smooth muscle cells - Muscle contraction" 29 "Plasma membrane" "Nucleoplasm, Cytosol" "CAB037078: , HPA045599: , HPA077782: " "unprognostic (4.12e-2)" "unprognostic (1.04e-1)" "unprognostic (1.23e-1)" "unprognostic (2.55e-2)" "unprognostic (2.36e-1)" "unprognostic (4.16e-2)" "unprognostic (7.10e-3)" "unprognostic (2.27e-1)" "unprognostic (4.52e-3)" "potential prognostic unfavorable (1.03e-5)" "potential prognostic favorable (9.97e-6)" "unprognostic (5.05e-2)" "unprognostic (3.76e-1)" "unprognostic (1.54e-1)" "unprognostic (5.94e-2)" "unprognostic (9.00e-2)" "unprognostic (7.80e-2)" "unprognostic (4.16e-2)" "unprognostic (3.89e-3)" "unprognostic (1.70e-1)" "unprognostic (6.99e-2)" "unprognostic (4.22e-2)" "unprognostic (4.88e-2)" "unprognostic (8.14e-2)" "unprognostic (4.20e-2)" "unprognostic (3.74e-2)" "unprognostic (6.70e-2)" "potential prognostic unfavorable (5.12e-5)" "unprognostic (1.50e-1)" "unprognostic (2.63e-3)" "unprognostic (3.54e-2)" CFLAR "c-FLIP, CASH, CASP8AP1, Casper, cFLIP, CLARP, FLAME, FLIP, I-FLICE, MRIT" ENSG00000003402 "CASP8 and FADD like apoptosis regulator" O15519 2 201116154-201176687 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Apoptosis, Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 787.2;Myonuclei: 754.3;Neutrophil progenitors: 823.9;Neutrophils: 2588.8;Platelets: 789.2" "Cell type enhanced" "Detected in all" "endothelial cell: 507.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "neutrophil: 394.0" "Lineage enriched" "Detected in all" 6 "granulocytes: 394.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019044, CAB022157, CAB025216" Uncertain Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA Yes "Cluster 35: Neutrophils - Protein binding" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 25: Non-specific - Transcription" "Cluster 55: Lymphoma - Immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 34 "Nucleoplasm, Plasma membrane, Cytosol" "Nuclear bodies" "CAB022157: , CAB025216: , HPA019044: " "unprognostic (7.43e-2)" "unprognostic (3.75e-1)" "potential prognostic favorable (2.39e-4)" "unprognostic (2.25e-2)" "unprognostic (2.73e-1)" "unprognostic (7.45e-2)" "unprognostic (5.78e-2)" "unprognostic (9.01e-2)" "unprognostic (2.44e-2)" "unprognostic (8.71e-3)" "potential prognostic favorable (9.32e-4)" "unprognostic (1.47e-3)" "unprognostic (2.71e-1)" "unprognostic (2.21e-2)" "unprognostic (1.70e-1)" "unprognostic (9.02e-2)" "unprognostic (1.12e-2)" "unprognostic (2.94e-3)" "unprognostic (1.70e-1)" "unprognostic (1.62e-1)" "unprognostic (7.84e-2)" "unprognostic (3.92e-2)" "unprognostic (1.38e-3)" "unprognostic (6.65e-2)" "unprognostic (6.20e-3)" "unprognostic (1.26e-2)" "unprognostic (2.10e-1)" "unprognostic (2.53e-1)" "unprognostic (1.45e-1)" "unprognostic (1.69e-1)" "unprognostic (8.77e-2)" CFP PFC ENSG00000126759 "Complement factor properdin" P27918 X 47623172-47630305 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement alternate pathway, Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 79.3;lymphoid tissue: 50.0" "Cell type enhanced" "Detected in some" "Astrocytes: 2.5;Bergmann glia: 1.7;Brain excitatory neurons: 2.1;Brain inhibitory neurons: 2.3;cDC: 2.6;Kupffer cells: 1.0;Macrophages: 1.0;monocytes: 8.5;Neutrophils: 1.9;Oligodendrocyte progenitor cells: 1.1;Other brain neurons: 1.6;Podocytes: 1.0" "Cell type enriched" "Detected in many" 4 "leukocyte: 16.4" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 6.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 8 "classical monocyte: 1169.0;intermediate monocyte: 1275.0;myeloid DC: 995.2;neutrophil: 733.0;non-classical monocyte: 872.6" "Group enriched" "Detected in all" 46 "dendritic cells: 995.2;granulocytes: 733.0;monocytes: 1275.0" "Cancer enriched" "Detected in some" 9 "Leukemia: 12.2" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Colon - Macrophages, Kidney - Macrophages, Lung - Neutrophils_2, Minor Salivary Gland - Macrophages, Skeletal muscle - Macrophages, Spleen - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA072644 Approved Vesicles "Secreted to blood" Immunity NA NA 18400000000 2400000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 15: Non-specific - Transcription" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 102: Non-specific - Mixed function" 23 Vesicles "HPA072644: " "unprognostic (3.34e-1)" "unprognostic (1.84e-3)" "unprognostic (3.61e-2)" "unprognostic (8.29e-2)" "unprognostic (1.36e-3)" "potential prognostic favorable (1.40e-6)" "unprognostic (7.87e-2)" "unprognostic (2.21e-1)" "unprognostic (8.88e-3)" "unprognostic (1.16e-3)" "potential prognostic favorable (7.15e-4)" "unprognostic (1.02e-1)" "unprognostic (2.71e-1)" "unprognostic (1.53e-3)" "unprognostic (3.44e-2)" "unprognostic (1.41e-3)" "unprognostic (1.50e-1)" "unprognostic (3.08e-2)" "unprognostic (1.68e-1)" "unprognostic (2.58e-1)" "unprognostic (2.94e-2)" "unprognostic (3.15e-1)" CFTR "ABC35, ABCC7, CF, CFTR/MRP, dJ760C5.1, MRP7, TNR-CFTR" ENSG00000001626 "CF transmembrane conductance regulator" P13569 7 117287120-117715971 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Isomerase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 47.0;intestine: 42.2;pancreas: 187.0" "Cell type enhanced" "Detected in many" "Enteric stem cells: 290.2;Pancreatic duct cells: 3336.0;Respiratory ionocytes: 767.1;Salivary acinar cells: 332.1;Salivary ionocytes: 1519.9" "Cell type enhanced" "Detected in many" "oligodendrocyte: 247.2" "Group enriched" "Detected in many" 4 "Colon Adenocarcinoma (TCGA): 42.5;Kidney Chromophobe (TCGA): 86.1;Pancreatic Adenocarcinoma (TCGA): 43.4;Rectum Adenocarcinoma (TCGA): 43.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 24.2;Gastric cancer: 9.6" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Skin - Eccrine sweat gland cells, Testis - Early spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB001951, HPA021939, HPA079652" Enhanced NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 11: White matter - Signal transduction" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 373 "CAB001951: , HPA021939: , HPA079652: " "unprognostic (3.74e-2)" "unprognostic (2.21e-1)" "unprognostic (1.75e-2)" "potential prognostic favorable (1.43e-4)" "unprognostic (5.50e-3)" "unprognostic (8.10e-3)" "unprognostic (6.36e-2)" "unprognostic (5.71e-2)" "unprognostic (4.70e-2)" "potential prognostic favorable (3.02e-4)" "unprognostic (3.66e-1)" "unprognostic (3.11e-2)" "unprognostic (1.73e-1)" "unprognostic (1.97e-1)" "unprognostic (1.77e-2)" "unprognostic (2.58e-2)" "unprognostic (2.22e-1)" "unprognostic (6.31e-2)" "unprognostic (5.19e-3)" "unprognostic (2.64e-1)" "unprognostic (1.39e-1)" "unprognostic (2.58e-1)" "unprognostic (1.64e-3)" CGA "FSHA, GPA1, GPHa, GPHA1, HCG, LHA, TSHA" ENSG00000135346 "Glycoprotein hormones, alpha polypeptide" P01215 6 87085498-87095106 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Hormone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "pituitary gland: 6387.3" "Cell type enriched" "Detected in some" 17 "Syncytiotrophoblasts: 124496.5" "Cell type enriched" "Detected in single" 5 "ependymal cell: 4.7" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 69.0;Testicular Germ Cell Tumor (TCGA): 61.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 14 "cervical cancer: 417.4;testis cancer: 1324.5" "Pituitary gland - Gonadotropes, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells" "Region enriched" "Detected in many" 6 "hypothalamus: 22.2" "Region enriched" "Detected in all" 18 "hypothalamus: 110.4" "CAB023350, HPA029698" Enhanced "Secreted to blood" Hormone NA NA "Cluster 20: Pituitary gland - Hormone signaling" "Cluster 46: Brainstem - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 4 "CAB023350: , HPA029698: " "unprognostic (7.10e-2)" "unprognostic (2.31e-1)" "unprognostic (1.03e-3)" "unprognostic (1.87e-1)" "unprognostic (6.53e-2)" "unprognostic (4.02e-2)" "unprognostic (1.03e-2)" "unprognostic (9.55e-3)" "unprognostic (2.78e-1)" "unprognostic (3.05e-2)" "unprognostic (2.04e-1)" "unprognostic (2.36e-1)" "unprognostic (1.34e-1)" "unprognostic (1.25e-1)" "unprognostic (4.45e-2)" "unprognostic (1.39e-1)" "unprognostic (7.05e-2)" CGAS "C6orf150, h-cGAS, MB21D1" ENSG00000164430 "Cyclic GMP-AMP synthase" Q8N884 6 73413515-73452297 "Enzymes, Predicted intracellular proteins" "Antiviral defense, DNA damage, DNA repair, Host-virus interaction, Immunity, Innate immunity" "DNA-binding, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 13.2" "Cell type enhanced" "Detected in many" "Macrophages: 51.1;Monocyte progenitors: 109.8;monocytes: 84.5;Neutrophil progenitors: 103.5;Neutrophils: 109.3;pDCs: 47.7;Plasma cells: 66.4;T-cells: 46.7" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 51.0;leukocyte: 57.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Skeletal muscle - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA031700, HPA031701, HPA031702" Enhanced Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 75: Non-specific - Chaperones and protein folding" 17 Nucleoplasm "Nuclear bodies, Cytosol" "HPA031700: , HPA031701: , HPA031702: " "unprognostic (1.02e-1)" "unprognostic (1.76e-1)" "unprognostic (1.42e-3)" "unprognostic (1.99e-2)" "unprognostic (1.62e-3)" "unprognostic (9.97e-3)" "unprognostic (3.30e-2)" "unprognostic (1.09e-1)" "unprognostic (5.78e-2)" "unprognostic (7.70e-2)" "unprognostic (2.30e-2)" "unprognostic (3.58e-2)" "unprognostic (7.61e-3)" "unprognostic (4.11e-2)" "unprognostic (1.69e-2)" "unprognostic (1.68e-1)" "unprognostic (7.42e-3)" "unprognostic (8.08e-2)" "potential prognostic unfavorable (9.80e-4)" "unprognostic (1.84e-1)" "unprognostic (2.96e-1)" "unprognostic (6.18e-3)" "unprognostic (1.21e-2)" "unprognostic (3.03e-2)" "unprognostic (1.35e-1)" "unprognostic (1.64e-1)" "unprognostic (8.72e-2)" CGB1 ENSG00000267631 "Chorionic gonadotropin subunit beta 1" A6NKQ9 19 49035569-49036895 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 7 "pancreas: 2.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "HPA038925, HPA038934, CAB080127" Supported "Secreted to blood" Hormone NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 49: HMC-1 - Innate immune response" "CAB080127: , HPA038925: , HPA038934: " CGB2 ENSG00000104818 "Chorionic gonadotropin subunit beta 2" Q6NT52 19 49031890-49033238 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "testis: 1.4" "Cell type enriched" "Detected in some" 4 "Syncytiotrophoblasts: 9.3" "Cancer enhanced" "Detected in some" "Ovary Serous Cystadenocarcinoma (TCGA): 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "HPA038925, HPA038934" Supported "Secreted in other tissues" Hormone NA NA "Cluster 67: Testis - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." "HPA038925: , HPA038934: " "unprognostic (1.93e-1)" "unprognostic (4.00e-1)" "unprognostic (2.24e-1)" "unprognostic (3.19e-1)" CGB3 CGB ENSG00000104827 "Chorionic gonadotropin subunit beta 3" P0DN86 19 49022869-49024333 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "pancreas: 2.2;pituitary gland: 2.5;placenta: 9.3" "Cell type enriched" "Detected in some" 6 "Syncytiotrophoblasts: 952.9" "Group enriched" "Detected in many" 5 "Pancreatic Adenocarcinoma (TCGA): 16.5;Testicular Germ Cell Tumor (TCGA): 21.4" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 4.0" "Pituitary gland - Gonadotropes" "CAB000042, CAB010884, HPA038925, HPA038934" Enhanced "Secreted to blood" Hormone NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 25: Non-specific - Transcription" "Cluster 34: Testis cancer - Unknown function" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." 2 "CAB000042: , CAB010884: , HPA038925: , HPA038934: " "potential prognostic unfavorable (1.81e-4)" "unprognostic (4.90e-3)" "unprognostic (2.65e-1)" "unprognostic (2.81e-3)" "unprognostic (3.32e-2)" "unprognostic (6.76e-2)" "unprognostic (4.12e-2)" "unprognostic (2.81e-1)" CGB5 HCG ENSG00000189052 "Chorionic gonadotropin subunit beta 5" P0DN86 19 49043848-49045311 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "pituitary gland: 6.6;placenta: 24.2" "Cell type enriched" "Detected in some" 5 "Syncytiotrophoblasts: 19.5" "Cancer enhanced" "Detected in many" "Pancreatic Adenocarcinoma (TCGA): 78.4;Testicular Germ Cell Tumor (TCGA): 39.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Pituitary gland - Gonadotropes" "HPA038925, HPA038934" Supported "Secreted to blood" Hormone NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 72: Neuronal - Signal transduction" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." 2 "HPA038925: , HPA038934: " "unprognostic (3.71e-3)" "unprognostic (2.98e-2)" "unprognostic (1.41e-1)" "unprognostic (3.75e-1)" "unprognostic (1.18e-3)" "potential prognostic unfavorable (7.09e-4)" "unprognostic (9.63e-3)" "potential prognostic unfavorable (4.90e-5)" "unprognostic (1.93e-1)" CGB7 CG-beta-a ENSG00000196337 "Chorionic gonadotropin subunit beta 7" P0DN87 19 49054274-49058860 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "pancreas: 2.8;skeletal muscle: 2.4;skin 1: 2.7" "Cell type enriched" "Detected in some" 8 "Syncytiotrophoblasts: 85.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Pancreatic Adenocarcinoma (TCGA): 1.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Pituitary gland - Gonadotropes" "HPA038925, HPA038934" Supported "Secreted in other tissues" "No annotated function" NA NA "Cluster 54: Non-specific - Ribosome" "Cluster 46: Brainstem - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." "HPA038925: , HPA038934: " "unprognostic (1.20e-2)" "unprognostic (2.90e-1)" "unprognostic (3.39e-2)" "unprognostic (1.23e-1)" "unprognostic (1.08e-1)" "potential prognostic unfavorable (3.19e-4)" "unprognostic (1.03e-2)" "unprognostic (3.19e-1)" CGB8 ENSG00000213030 "Chorionic gonadotropin subunit beta 8" P0DN86 19 49047638-49049111 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 62 "pituitary gland: 4.6;placenta: 17.6" "Cell type enriched" "Detected in some" 7 "Syncytiotrophoblasts: 41.4" "Group enriched" "Detected in some" 7 "Pancreatic Adenocarcinoma (TCGA): 11.4;Testicular Germ Cell Tumor (TCGA): 37.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 25.3" "Pituitary gland - Gonadotropes" "HPA038925, HPA038934" Supported "Secreted to blood" Hormone NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 72: Neuronal - Signal transduction" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." 2 "HPA038925: , HPA038934: " "unprognostic (2.04e-2)" "unprognostic (2.60e-1)" "unprognostic (7.38e-2)" "unprognostic (2.03e-3)" "unprognostic (5.52e-2)" "potential prognostic unfavorable (5.42e-4)" "unprognostic (2.80e-1)" CGGBP1 "CGGBP, p20-CGGBP" ENSG00000163320 "CGG triplet repeat binding protein 1" Q9UFW8 3 88051944-88149885 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 490.2;Epicardial cells: 482.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035568, HPA037017" Supported Enhanced Nucleoplasm NA NA "Cluster 32: Basophils - Transcription" "Cluster 80: Thymus - Adaptive immune response" "Cluster 55: Non-specific - Transcription" "Cluster 13: Non-specific - Mixed function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 18 Nucleoplasm "HPA035568: , HPA037017: " "unprognostic (9.46e-3)" "unprognostic (1.77e-1)" "unprognostic (7.28e-2)" "unprognostic (9.06e-2)" "unprognostic (4.68e-1)" "unprognostic (1.68e-2)" "unprognostic (5.25e-2)" "unprognostic (4.06e-1)" "unprognostic (4.57e-3)" "unprognostic (3.43e-2)" "potential prognostic favorable (3.34e-6)" "unprognostic (1.50e-2)" "unprognostic (2.71e-1)" "unprognostic (3.22e-3)" "unprognostic (7.97e-2)" "unprognostic (1.95e-2)" "unprognostic (2.74e-1)" "unprognostic (1.35e-1)" "unprognostic (4.31e-2)" "unprognostic (2.70e-1)" "unprognostic (2.12e-2)" "unprognostic (3.65e-2)" "unprognostic (4.21e-3)" "unprognostic (4.64e-2)" "unprognostic (2.42e-2)" "unprognostic (1.22e-1)" "unprognostic (1.05e-1)" "unprognostic (1.46e-2)" "unprognostic (1.14e-2)" "unprognostic (1.16e-1)" "unprognostic (2.27e-1)" CGN KIAA1319 ENSG00000143375 Cingulin Q9P2M7 1 151510510-151538692 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 53.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 272.4;Alveolar cells type 2: 85.1;Colonocytes: 143.1;Enterocytes: 167.0;Foveolar cells: 94.2;Mesothelial cells: 88.7;Respiratory ciliated cells: 98.5;Transitional alveolar cells: 108.4;Urothelial cells: 88.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Kidney - Macrophages, Minor Salivary Gland - Minor salivary glandular cells, Skin - Keratinocyte (granular), Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "CAB017193, HPA027586, HPA027587, HPA027657" Enhanced Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 77: Intestine - Digestion" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 28 "Plasma membrane, Cell Junctions" "CAB017193: , HPA027586: , HPA027587: , HPA027657: " "unprognostic (2.51e-1)" "unprognostic (7.18e-2)" "potential prognostic favorable (2.84e-4)" "unprognostic (6.86e-2)" "unprognostic (9.41e-3)" "unprognostic (2.16e-2)" "unprognostic (1.80e-1)" "unprognostic (1.85e-2)" "unprognostic (2.74e-1)" "unprognostic (1.99e-1)" "potential prognostic favorable (2.92e-11)" "unprognostic (3.91e-3)" "unprognostic (1.19e-1)" "unprognostic (1.30e-1)" "unprognostic (7.25e-2)" "unprognostic (5.76e-2)" "unprognostic (3.59e-3)" "unprognostic (1.44e-1)" "unprognostic (1.10e-1)" "unprognostic (6.34e-3)" "unprognostic (1.32e-1)" "potential prognostic unfavorable (7.10e-4)" "unprognostic (4.72e-2)" "unprognostic (2.21e-1)" "unprognostic (8.25e-2)" "unprognostic (1.13e-1)" "unprognostic (3.58e-1)" "unprognostic (2.18e-1)" "unprognostic (1.83e-1)" "unprognostic (1.91e-1)" "unprognostic (1.72e-1)" CGNL1 "FLJ14957, JACOP, KIAA1749, PCING" ENSG00000128849 "Cingulin like 1" Q0VF96 15 57375967-57550717 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 63.8" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 973.6;Esophageal apical cells: 381.8;Loop of henle epithelial cells: 963.8;Podocytes: 590.0;Prostatic glandular cells: 345.2;Proximal tubule cells: 512.0;Renal collecting duct intercalated cells: 655.1;Renal connecting tubule cells: 312.0;Salivary acinar cells: 282.0" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 208.3;endothelial cell: 760.9" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 88.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 34.7" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 1, Minor Salivary Gland - Minor salivary glandular cells, Stomach - Chief cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013500, HPA056911, HPA069214" Enhanced Supported "Nuclear bodies,Cell Junctions" No No "Cluster 76: Non-specific - Metabolism" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 15: Kidney cancer - Membrane components" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 10 "Cell Junctions" "Nuclear bodies" "CAB013500: , HPA056911: , HPA069214: " "unprognostic (3.53e-3)" "unprognostic (2.39e-2)" "unprognostic (1.67e-2)" "unprognostic (2.34e-1)" "unprognostic (4.13e-2)" "unprognostic (1.73e-1)" "unprognostic (1.98e-1)" "potential prognostic unfavorable (6.97e-7)" "unprognostic (1.79e-3)" "unprognostic (4.67e-1)" "potential prognostic favorable (2.83e-6)" "unprognostic (1.43e-2)" "unprognostic (5.21e-2)" "unprognostic (1.46e-3)" "unprognostic (3.37e-3)" "unprognostic (9.15e-3)" "unprognostic (2.72e-1)" "unprognostic (2.27e-1)" "unprognostic (2.37e-1)" "unprognostic (3.73e-2)" "unprognostic (1.19e-1)" "unprognostic (4.53e-2)" "unprognostic (1.44e-1)" "unprognostic (5.77e-2)" "unprognostic (1.21e-2)" "unprognostic (2.16e-1)" "unprognostic (2.25e-1)" "unprognostic (1.51e-2)" "unprognostic (3.79e-1)" "unprognostic (6.20e-3)" "unprognostic (4.13e-2)" CGREF1 CGR11 ENSG00000138028 "Cell growth regulator with EF-hand domain 1" Q99674 2 27098889-27119128 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Cell cycle, Growth arrest" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 44.6;salivary gland: 24.5" "Cell type enriched" "Detected in many" 7 "Oocytes: 280.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Fibroblasts_2, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Spleen - Smooth muscle cells, Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008241, HPA071103" Uncertain Approved "Golgi apparatus" "Secreted in brain" "Cell adhesion" NA NA 1900000 "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" 16 "Golgi apparatus" "HPA008241: , HPA071103: " "unprognostic (2.01e-1)" "unprognostic (5.61e-2)" "unprognostic (1.90e-1)" "potential prognostic unfavorable (9.77e-4)" "unprognostic (1.45e-1)" "unprognostic (2.18e-1)" "unprognostic (9.59e-2)" "unprognostic (3.78e-2)" "unprognostic (3.76e-2)" "unprognostic (5.34e-2)" "unprognostic (3.51e-2)" "unprognostic (4.04e-1)" "potential prognostic unfavorable (8.09e-4)" "unprognostic (4.25e-2)" "unprognostic (1.96e-1)" "unprognostic (2.35e-1)" "unprognostic (1.50e-2)" "unprognostic (5.41e-2)" "unprognostic (1.10e-1)" "unprognostic (4.37e-1)" "unprognostic (1.01e-1)" "unprognostic (1.27e-2)" "unprognostic (5.22e-2)" "unprognostic (2.37e-1)" "unprognostic (1.05e-1)" "unprognostic (4.12e-1)" "unprognostic (1.97e-1)" "unprognostic (2.83e-2)" "unprognostic (4.38e-2)" CGRRF1 "CGR19, RNF197" ENSG00000100532 "Cell growth regulator with ring finger domain 1" Q99675 14 54509812-54539292 "Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Growth arrest" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 127.4;Late primary spermatocytes: 221.8;Platelets: 221.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002930 Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 32: Basophils - Transcription" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 55: Non-specific - Transcription" "Cluster 3: Rhabdoid - Membrane components" "Cluster 47: Platelets - Hemostasis" 33 Nucleoplasm Vesicles "HPA002930: " "unprognostic (1.14e-1)" "unprognostic (2.84e-1)" "unprognostic (1.44e-2)" "unprognostic (2.20e-2)" "unprognostic (7.13e-2)" "unprognostic (2.36e-1)" "unprognostic (1.14e-1)" "unprognostic (2.75e-1)" "unprognostic (2.01e-1)" "unprognostic (1.71e-2)" "potential prognostic favorable (2.99e-7)" "unprognostic (1.39e-3)" "unprognostic (1.06e-2)" "potential prognostic unfavorable (1.47e-4)" "unprognostic (2.34e-2)" "unprognostic (2.97e-1)" "unprognostic (1.49e-1)" "unprognostic (4.72e-2)" "unprognostic (2.58e-1)" "unprognostic (1.01e-1)" "unprognostic (5.65e-2)" "unprognostic (4.45e-2)" "unprognostic (1.30e-1)" "unprognostic (1.67e-1)" "unprognostic (3.56e-1)" "unprognostic (1.68e-1)" "unprognostic (3.25e-1)" "unprognostic (4.99e-2)" "unprognostic (2.12e-1)" "unprognostic (2.42e-1)" "unprognostic (3.69e-2)" CH25H ENSG00000138135 "Cholesterol 25-hydroxylase" O95992 10 89205629-89207317 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 33.0" "Cell type enhanced" "Detected in many" "Breast lactating cells: 97.3;Epididymal principal cells: 80.5;Esophageal basal cells: 40.3;Fibroblasts: 47.8;Macrophages: 34.7;Microglia: 100.6;Ocular epithelial cells: 41.1;Pericytes: 150.2;Smooth muscle cells: 40.2;Vascular smooth muscle cells: 214.2" "Cell type enriched" "Detected in many" 7 "central nervous system macrophage: 95.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Brain cancer: 2.7;thyroid cancer: 1.0;Uterine cancer: 4.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 44: Bone marrow - Nuclear processes" "Cluster 44: Non-specific - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 103: Non-specific - Basic cellular processes" 2 "unprognostic (1.04e-3)" "unprognostic (8.04e-3)" "unprognostic (2.16e-3)" "unprognostic (2.33e-3)" "unprognostic (1.71e-1)" "unprognostic (1.89e-3)" "unprognostic (1.79e-2)" "unprognostic (2.57e-1)" "unprognostic (1.73e-1)" "unprognostic (2.82e-3)" "unprognostic (2.96e-2)" "unprognostic (6.21e-2)" "potential prognostic favorable (1.16e-4)" "unprognostic (1.18e-3)" "unprognostic (2.62e-2)" "potential prognostic unfavorable (9.73e-4)" "unprognostic (7.61e-2)" "potential prognostic unfavorable (7.31e-4)" "unprognostic (1.12e-1)" "unprognostic (3.11e-1)" "unprognostic (3.48e-2)" "unprognostic (1.27e-1)" "unprognostic (4.60e-2)" "unprognostic (4.82e-1)" "unprognostic (2.73e-2)" "unprognostic (1.71e-2)" "unprognostic (3.27e-2)" CHAC1 MGC4504 ENSG00000128965 "ChaC glutathione specific gamma-glutamylcyclotransferase 1" Q9BUX1 15 40952962-40956512 "Enzymes, Predicted intracellular proteins" "Apoptosis, Neurogenesis, Notch signaling pathway, Unfolded protein response" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 64.7;skeletal muscle: 108.2" "Cell type enhanced" "Detected in many" "Epicardial cells: 125.1;Epididymal efferent duct ciliated cells: 17.6;Epididymal principal cells: 18.7;Esophageal apical cells: 68.9;Fallopian tube ciliated cells: 17.4;Foveolar cells: 23.4;Gastric chief cells: 24.0;Mesothelial cells: 31.0;Pancreatic acinar cells: 15.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Skin - Hair cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042708, HPA043505" Approved Approved Mitochondria NA NA "Cluster 24: Non-specific - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 4 Mitochondria "HPA042708: , HPA043505: " "unprognostic (3.50e-1)" "unprognostic (2.47e-2)" "unprognostic (7.78e-2)" "unprognostic (1.18e-1)" "unprognostic (1.56e-1)" "unprognostic (3.59e-2)" "unprognostic (3.14e-3)" "potential prognostic unfavorable (1.34e-4)" "unprognostic (2.57e-2)" "unprognostic (3.43e-1)" "potential prognostic unfavorable (7.58e-7)" "unprognostic (6.60e-3)" "potential prognostic unfavorable (1.06e-4)" "unprognostic (1.15e-2)" "unprognostic (1.55e-1)" "unprognostic (2.29e-3)" "unprognostic (4.17e-1)" "unprognostic (7.60e-2)" "potential prognostic favorable (9.70e-4)" "unprognostic (1.08e-1)" "unprognostic (3.26e-1)" "unprognostic (4.66e-1)" "unprognostic (8.26e-2)" "unprognostic (1.53e-1)" "unprognostic (1.62e-1)" "unprognostic (6.23e-2)" "unprognostic (8.22e-2)" "unprognostic (1.69e-2)" "unprognostic (1.41e-1)" "unprognostic (1.19e-2)" "unprognostic (4.39e-2)" CHAC2 GCG1 ENSG00000143942 "ChaC glutathione specific gamma-glutamylcyclotransferase 2" Q8WUX2 2 53767804-53775196 "Enzymes, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 34.7;Late primary spermatocytes: 65.4;Plasma cells: 35.8;Respiratory ionocytes: 30.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast), Spleen - Mitotic cells (Spleen), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049235 Approved Approved Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 1: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 44: Plasma cells - Antibody production & secretion" 7 Cytosol "HPA049235: " "unprognostic (9.15e-3)" "unprognostic (1.38e-1)" "unprognostic (5.25e-2)" "unprognostic (8.41e-2)" "unprognostic (4.66e-2)" "unprognostic (5.11e-2)" "unprognostic (2.58e-2)" "unprognostic (1.35e-1)" "unprognostic (1.07e-3)" "unprognostic (2.24e-2)" "unprognostic (1.65e-2)" "unprognostic (1.53e-2)" "unprognostic (4.67e-2)" "potential prognostic unfavorable (1.81e-6)" "unprognostic (3.10e-3)" "unprognostic (1.13e-2)" "unprognostic (2.04e-1)" "unprognostic (5.72e-3)" "unprognostic (9.49e-2)" "unprognostic (4.37e-2)" "unprognostic (2.05e-2)" "unprognostic (2.76e-2)" "unprognostic (2.00e-1)" "unprognostic (4.70e-3)" "unprognostic (9.20e-3)" "potential prognostic unfavorable (3.25e-4)" "unprognostic (1.04e-3)" "unprognostic (1.74e-1)" "unprognostic (6.35e-2)" "unprognostic (1.49e-1)" "unprognostic (1.04e-3)" CHAD SLRR4A ENSG00000136457 Chondroadherin O15335 17 50464496-50468906 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 34.2;liver: 36.8;pancreas: 30.3" "Cell type enhanced" "Detected in many" "Adipocytes: 8.6;Breast hormone-responsive cells: 9.8;Goblet cells: 13.4;Mesothelial cells: 7.1;Myonuclei: 16.3;Oligodendrocyte progenitor cells: 14.8;Papillary tip epithelial cells: 16.2;Proximal tubule cells: 9.4;Salivary duct cells: 15.3" "Cell type enhanced" "Detected in some" "oligodendrocyte precursor cell: 16.5;upper rhombic lip: 10.0" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 43.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 53 "memory B-cell: 21.6;naive B-cell: 8.1" "Lineage enriched" "Detected in single" 76 "B-cells: 21.6" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA018241 Enhanced "Secreted to extracellular matrix" "No annotated function" NA NA 8400000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 1 "HPA018241: " "unprognostic (4.71e-2)" "unprognostic (5.07e-3)" "unprognostic (2.13e-1)" "unprognostic (1.09e-1)" "unprognostic (3.45e-1)" "unprognostic (1.78e-1)" "unprognostic (1.30e-1)" "unprognostic (3.09e-2)" "unprognostic (2.62e-1)" "potential prognostic favorable (4.37e-4)" "unprognostic (7.60e-3)" "unprognostic (3.77e-3)" "unprognostic (9.37e-2)" "unprognostic (6.00e-2)" "unprognostic (5.48e-3)" "unprognostic (1.27e-1)" "unprognostic (1.41e-2)" "unprognostic (8.47e-2)" "unprognostic (2.34e-2)" "unprognostic (2.78e-1)" "unprognostic (1.04e-1)" "unprognostic (3.13e-3)" CHADL SLRR4B ENSG00000100399 "Chondroadherin like" Q6NUI6 22 41229510-41240931 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 109.8" "Cell type enhanced" "Detected in many" "Breast lactating cells: 40.5;Early spermatids: 36.2;Megakaryocytes: 30.9;Melanocytes: 45.7;Müller glia: 39.8;Oligodendrocytes: 102.9;Retinal pigment epithelial cells: 46.9;Schwann cells: 70.9" "Group enriched" "Detected in all" 4 "committed oligodendrocyte precursor: 96.2;oligodendrocyte: 139.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.2" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in some" "Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Pituitary gland - Undifferentiated cells (Pituitary gland), Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA005696, HPA024654" Uncertain "Secreted to extracellular matrix" "No annotated function" NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 69: Skin cancer - ECM organization" "Cluster 61: Schwann cells & Melanocytes - Mixed function" "HPA005696: , HPA024654: " "unprognostic (5.01e-2)" "unprognostic (1.81e-1)" "unprognostic (2.28e-1)" "unprognostic (5.07e-2)" "unprognostic (1.94e-1)" "unprognostic (6.36e-2)" "unprognostic (2.96e-1)" "unprognostic (1.45e-1)" "unprognostic (8.87e-3)" "unprognostic (6.73e-2)" "validated prognostic favorable (2.83e-4)" "validated prognostic favorable (2.38e-4)" "potential prognostic favorable (4.22e-7)" "unprognostic (2.37e-2)" "unprognostic (4.93e-2)" "unprognostic (2.49e-3)" "unprognostic (1.48e-1)" "unprognostic (1.46e-1)" "unprognostic (9.29e-2)" "unprognostic (1.52e-2)" "unprognostic (1.79e-1)" "unprognostic (4.32e-3)" "unprognostic (9.81e-3)" "unprognostic (2.20e-2)" "unprognostic (3.28e-1)" "unprognostic (2.93e-2)" "unprognostic (2.00e-1)" "unprognostic (1.21e-1)" "unprognostic (2.22e-2)" CHAF1A "CAF-1, CAF1, CAF1B, CAF1P150, MGC71229, P150" ENSG00000167670 "Chromatin assembly factor 1 subunit A" Q13111 19 4402640-4445018 "Essential proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair, DNA replication" "Chaperone, Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 29.6" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 135.0;Early primary spermatocytes: 156.0;Erythrocyte progenitors: 132.0;Megakaryocyte progenitors: 90.1;Monocyte progenitors: 67.8;pDCs: 164.9;Respiratory deuterosomal cells: 67.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 15.7" "Group enriched" "Detected in many" 4 "dendritic cells: 15.7;granulocytes: 4.7" "Low cancer specificity" "Detected in all" "Pituitary gland - Corticotropes, Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB015186 Enhanced Supported Nucleoplasm,Cytosol NA Yes "Cluster 29: Non-specific - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 37: Neurons - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 97 Nucleoplasm Cytosol "CAB015186: " "unprognostic (1.20e-1)" "unprognostic (3.90e-2)" "unprognostic (1.60e-1)" "unprognostic (2.09e-1)" "unprognostic (1.50e-1)" "unprognostic (9.28e-2)" "unprognostic (2.07e-1)" "unprognostic (1.12e-2)" "unprognostic (1.89e-3)" "potential prognostic unfavorable (7.16e-4)" "unprognostic (1.76e-3)" "unprognostic (2.51e-1)" "unprognostic (8.47e-2)" "unprognostic (6.67e-3)" "potential prognostic unfavorable (4.73e-5)" "unprognostic (2.76e-3)" "unprognostic (1.42e-2)" "unprognostic (2.72e-2)" "unprognostic (1.14e-2)" "unprognostic (2.36e-1)" "unprognostic (1.54e-1)" "unprognostic (1.35e-2)" "unprognostic (1.54e-2)" "unprognostic (2.18e-2)" "unprognostic (2.97e-2)" "unprognostic (7.47e-3)" "unprognostic (2.18e-2)" "potential prognostic favorable (6.18e-5)" "unprognostic (4.42e-1)" "unprognostic (2.58e-2)" "unprognostic (4.21e-2)" CHAF1B "CAF-1, CAF1, CAF1A, CAF1P60, MPHOSPH7, MPP7" ENSG00000159259 "Chromatin assembly factor 1 subunit B" Q13112 21 36385392-36419015 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair, DNA replication" "Chaperone, Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 14.6" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 29.8;Erythrocyte progenitors: 28.0;Respiratory deuterosomal cells: 40.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Minor Salivary Gland - Minor salivary glandular cells, Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA021679, CAB033604" Enhanced Supported Nucleoplasm NA Yes "Cluster 3: Non-specific - Nuclear processes" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 48: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 27: Non-specific - Cell proliferation" 57 Nucleoplasm "CAB033604: , HPA021679: " "unprognostic (3.20e-2)" "unprognostic (1.09e-2)" "unprognostic (5.28e-1)" "unprognostic (1.24e-1)" "unprognostic (3.80e-2)" "unprognostic (1.36e-1)" "unprognostic (5.19e-3)" "unprognostic (3.53e-2)" "unprognostic (3.27e-2)" "unprognostic (1.20e-2)" "validated prognostic unfavorable (1.14e-6)" "validated prognostic unfavorable (8.14e-5)" "potential prognostic unfavorable (2.29e-4)" "validated prognostic unfavorable (1.56e-5)" "validated prognostic unfavorable (1.58e-4)" "validated prognostic unfavorable (3.25e-4)" "validated prognostic unfavorable (1.30e-5)" "unprognostic (6.81e-2)" "unprognostic (2.07e-2)" "unprognostic (7.64e-2)" "unprognostic (3.60e-3)" "unprognostic (2.61e-2)" "unprognostic (6.79e-3)" "unprognostic (1.31e-2)" "unprognostic (2.43e-3)" "unprognostic (5.57e-2)" "unprognostic (3.05e-2)" "unprognostic (5.05e-2)" "unprognostic (5.21e-2)" "unprognostic (3.99e-1)" "unprognostic (4.19e-1)" CHAMP1 "C13orf8, CAMP, CHAMP, ZNF828" ENSG00000198824 "Chromosome alignment maintaining phosphoprotein 1" Q96JM3 13 114314482-114337626 "Human disease related genes, Predicted intracellular proteins" "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "HPA006623, HPA008900" Enhanced Enhanced "Nucleoplasm,Nuclear bodies" NA No "Cluster 5: Non-specific - Cell proliferation" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 16: Non-specific - Transcription" "Cluster 19: Non-specific - Unknown function" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 26 Nucleoplasm "Nuclear bodies" "HPA006623: , HPA008900: " "potential prognostic favorable (6.31e-4)" "unprognostic (4.45e-2)" "unprognostic (5.94e-2)" "unprognostic (8.59e-2)" "unprognostic (1.08e-1)" "unprognostic (6.69e-2)" "unprognostic (2.74e-1)" "unprognostic (1.57e-1)" "unprognostic (4.96e-2)" "potential prognostic favorable (2.55e-6)" "unprognostic (7.13e-3)" "unprognostic (1.38e-1)" "unprognostic (2.27e-2)" "unprognostic (2.83e-2)" "unprognostic (1.05e-2)" "unprognostic (2.94e-2)" "unprognostic (1.34e-2)" "unprognostic (6.85e-2)" "unprognostic (3.42e-1)" "unprognostic (5.90e-2)" "unprognostic (2.81e-2)" "unprognostic (5.51e-2)" "unprognostic (6.77e-2)" "unprognostic (2.70e-1)" "unprognostic (3.07e-1)" "unprognostic (7.70e-2)" "unprognostic (2.04e-1)" "unprognostic (4.10e-2)" "unprognostic (3.53e-2)" CHAT ENSG00000070748 "Choline O-acetyltransferase" P28329 10 49609095-49667942 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Neurotransmitter biosynthesis" "Acyltransferase, Transferase" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 3.7;placenta: 5.1" "Cell type enriched" "Detected in some" 14 "Tuft cells: 403.5" "Cell type enhanced" "Detected in some" "cerebellar inhibitory: 3.2;splatter: 3.0" "Not detected" "Not detected" "Region enhanced" "Detected in all" "cerebral cortex: 39.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Bone cancer: 3.8;Neuroblastoma: 4.8" "Colon - Colon enteroendocrine cells" "Region enhanced" "Detected in many" "basal ganglia: 20.6" "Group enriched" "Detected in some" 7 "basal ganglia: 8.5;pons: 9.1;spinal cord: 15.8" "CAB002313, HPA048547, CAB079053" Supported Supported NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 43: Hindbrain - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 95: Tuft cells - Chemosensory signaling" 3 "CAB002313: , CAB079053: , HPA048547: " "unprognostic (3.76e-3)" CHCHD1 "C10orf34, FLJ25854" ENSG00000172586 "Coiled-coil-helix-coiled-coil-helix domain containing 1" Q96BP2 10 73782047-73783652 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 311.7;Esophageal suprabasal cells: 234.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039046 Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Mitochondria,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 52: Non-specific - Mitochondria" "Cluster 97: Non-specific - Cellular respiration" 4 "Nucleoplasm, Mitochondria" "Nucleoli fibrillar center, Cytosol" "HPA039046: " "unprognostic (1.79e-1)" "unprognostic (9.49e-2)" "unprognostic (5.57e-2)" "unprognostic (2.86e-3)" "unprognostic (2.39e-1)" "unprognostic (1.61e-2)" "unprognostic (1.01e-1)" "potential prognostic favorable (6.03e-5)" "unprognostic (6.61e-2)" "unprognostic (9.88e-2)" "unprognostic (5.02e-2)" "unprognostic (2.25e-3)" "unprognostic (5.57e-2)" "potential prognostic unfavorable (2.19e-5)" "unprognostic (2.32e-2)" "unprognostic (9.81e-3)" "unprognostic (7.25e-2)" "unprognostic (3.16e-1)" "unprognostic (3.30e-1)" "unprognostic (4.59e-3)" "unprognostic (1.92e-1)" "unprognostic (9.43e-2)" "unprognostic (5.29e-2)" "unprognostic (3.46e-2)" "unprognostic (6.50e-2)" "unprognostic (3.47e-2)" "unprognostic (1.90e-1)" "unprognostic (3.32e-2)" "unprognostic (1.74e-1)" "unprognostic (1.51e-1)" "unprognostic (2.53e-1)" CHCHD10 "C22orf16, MIX17A, N27C7-4" ENSG00000250479 "Coiled-coil-helix-coiled-coil-helix domain containing 10" Q8WYQ3 22 23765834-23767972 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1596.3;skeletal muscle: 1222.7" "Cell type enhanced" "Detected in many" "Colonocytes: 1429.4;Enteric stem cells: 699.9;Enteric transient amplifying cells: 909.6;Enterocytes: 1161.4;Epididymal clear cells: 959.4;Goblet cells: 637.8;Hepatocytes: 1706.7;Hofbauer cells: 744.7;Parietal cells: 915.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 618.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003440 Enhanced Supported Mitochondria NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 23: Choroid plexus - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 97: Non-specific - Cellular respiration" 7 Mitochondria "HPA003440: " "unprognostic (1.71e-1)" "unprognostic (2.44e-1)" "unprognostic (5.02e-2)" "potential prognostic favorable (1.78e-4)" "unprognostic (1.94e-1)" "unprognostic (3.93e-2)" "unprognostic (5.78e-2)" "potential prognostic unfavorable (8.12e-5)" "unprognostic (7.26e-3)" "unprognostic (2.33e-1)" "potential prognostic favorable (9.80e-5)" "unprognostic (1.57e-1)" "potential prognostic favorable (2.01e-6)" "unprognostic (3.63e-1)" "unprognostic (2.74e-1)" "unprognostic (4.41e-2)" "unprognostic (1.58e-1)" "unprognostic (1.61e-1)" "unprognostic (1.05e-1)" "unprognostic (1.19e-1)" "unprognostic (1.49e-1)" "unprognostic (3.80e-1)" "unprognostic (2.17e-1)" "unprognostic (9.18e-2)" "unprognostic (1.63e-1)" "unprognostic (3.73e-2)" "unprognostic (2.46e-2)" "unprognostic (2.64e-2)" "unprognostic (1.21e-1)" "unprognostic (1.45e-3)" "unprognostic (1.88e-2)" CHCHD2 "C7orf17, MIX17B, MNRR1" ENSG00000106153 "Coiled-coil-helix-coiled-coil-helix domain containing 2" Q9Y6H1 7 56101573-56106476 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" Transcription Activator "Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1808.4;Esophageal suprabasal cells: 1814.9;Gastric progenitor cells: 1941.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027407, HPA052510" Approved Supported Mitochondria NA NA 11000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 67: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 66 Mitochondria "HPA027407: , HPA052510: " "unprognostic (8.20e-2)" "unprognostic (2.63e-3)" "unprognostic (1.75e-2)" "potential prognostic unfavorable (5.65e-4)" "unprognostic (2.24e-1)" "unprognostic (8.37e-2)" "unprognostic (1.17e-1)" "unprognostic (2.20e-2)" "potential prognostic unfavorable (2.04e-4)" "unprognostic (2.11e-2)" "potential prognostic favorable (2.25e-5)" "unprognostic (7.37e-3)" "unprognostic (9.98e-2)" "validated prognostic unfavorable (1.68e-4)" "validated prognostic unfavorable (1.92e-9)" "potential prognostic unfavorable (1.86e-4)" "unprognostic (2.19e-2)" "unprognostic (1.07e-1)" "unprognostic (2.20e-1)" "unprognostic (3.25e-2)" "unprognostic (9.51e-2)" "unprognostic (3.71e-1)" "unprognostic (2.32e-1)" "unprognostic (1.63e-1)" "unprognostic (1.68e-2)" "unprognostic (3.55e-2)" "unprognostic (1.93e-2)" "unprognostic (2.06e-1)" "unprognostic (1.43e-1)" "unprognostic (2.44e-1)" "unprognostic (1.22e-1)" CHCHD3 "FLJ20420, Mic19, MICOS19, MINOS3, PPP1R22" ENSG00000106554 "Coiled-coil-helix-coiled-coil-helix domain containing 3" Q9NX63 7 132784870-133082090 "Essential proteins, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 329.6;tongue: 227.3" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Minor Salivary Gland - Endothelial cells, Prostate - Smooth muscle cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042935 Enhanced Supported Mitochondria NA NA 10000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 23: Choroid plexus - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 55: Myocytes - Oxidative muscle function" 84 Mitochondria "HPA042935: " "unprognostic (4.44e-2)" "unprognostic (1.95e-1)" "unprognostic (1.27e-3)" "unprognostic (6.62e-2)" "unprognostic (2.35e-1)" "unprognostic (2.62e-1)" "unprognostic (8.90e-2)" "unprognostic (2.49e-1)" "unprognostic (1.52e-2)" "unprognostic (4.87e-3)" "potential prognostic favorable (8.47e-7)" "unprognostic (3.06e-2)" "unprognostic (1.02e-1)" "validated prognostic unfavorable (5.36e-4)" "validated prognostic unfavorable (1.83e-5)" "potential prognostic unfavorable (5.83e-4)" "unprognostic (4.02e-3)" "unprognostic (3.50e-1)" "unprognostic (2.21e-1)" "unprognostic (9.39e-2)" "unprognostic (2.19e-2)" "unprognostic (6.04e-2)" "unprognostic (2.14e-1)" "unprognostic (3.32e-1)" "unprognostic (8.99e-2)" "unprognostic (1.93e-2)" "unprognostic (1.52e-1)" "unprognostic (1.99e-1)" "unprognostic (1.49e-1)" "unprognostic (8.55e-2)" "unprognostic (2.84e-1)" CHCHD4 "FLJ31709, MIA40, TIMM40" ENSG00000163528 "Coiled-coil-helix-coiled-coil-helix domain containing 4" Q8N4Q1 3 14112077-14124870 "Essential proteins, Predicted intracellular proteins" "Protein transport, Translocation, Transport" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 46.5;Esophageal basal cells: 42.4;Parietal cells: 53.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034688, HPA063727" Uncertain Supported Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 14: Neurons - Synaptic function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 97: Non-specific - Cellular respiration" 7 Mitochondria "HPA034688: , HPA063727: " "unprognostic (2.42e-1)" "potential prognostic unfavorable (8.93e-4)" "unprognostic (2.37e-2)" "unprognostic (7.10e-2)" "unprognostic (3.72e-1)" "unprognostic (3.45e-1)" "unprognostic (8.02e-2)" "unprognostic (3.01e-1)" "unprognostic (2.45e-1)" "unprognostic (4.49e-2)" "potential prognostic favorable (4.80e-6)" "unprognostic (8.68e-3)" "unprognostic (5.79e-2)" "unprognostic (8.79e-3)" "potential prognostic unfavorable (3.07e-6)" "potential prognostic unfavorable (1.32e-4)" "unprognostic (1.56e-1)" "unprognostic (1.33e-1)" "unprognostic (2.19e-1)" "unprognostic (7.05e-2)" "unprognostic (1.66e-1)" "unprognostic (1.52e-2)" "unprognostic (1.95e-1)" "unprognostic (1.09e-1)" "unprognostic (3.16e-2)" "unprognostic (2.31e-1)" "unprognostic (3.15e-1)" "unprognostic (1.86e-1)" "unprognostic (2.24e-1)" "unprognostic (2.57e-1)" "unprognostic (3.90e-2)" CHCHD5 "C2orf9, MGC11104, MIC14, MIX14" ENSG00000125611 "Coiled-coil-helix-coiled-coil-helix domain containing 5" Q9BSY4 2 112584240-112589275 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 330.1;Late spermatids: 379.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038263 Approved Approved Mitochondria NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 70: Non-specific - Protein processing" "Cluster 39: Astrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 97: Non-specific - Cellular respiration" 3 Mitochondria "HPA038263: " "unprognostic (9.32e-3)" "unprognostic (1.06e-1)" "unprognostic (4.89e-2)" "unprognostic (1.61e-2)" "unprognostic (3.43e-1)" "unprognostic (1.82e-1)" "unprognostic (2.35e-1)" "unprognostic (2.68e-2)" "unprognostic (8.31e-2)" "unprognostic (7.67e-2)" "unprognostic (6.27e-2)" "unprognostic (7.42e-2)" "unprognostic (2.81e-1)" "unprognostic (5.36e-2)" "unprognostic (5.49e-2)" "unprognostic (1.12e-2)" "unprognostic (3.30e-1)" "unprognostic (1.30e-1)" "unprognostic (1.82e-1)" "unprognostic (9.08e-3)" "unprognostic (8.76e-2)" "unprognostic (4.69e-2)" "unprognostic (4.23e-1)" "unprognostic (1.52e-1)" "unprognostic (4.44e-1)" "unprognostic (2.05e-1)" "unprognostic (1.82e-1)" "unprognostic (1.14e-1)" "unprognostic (1.72e-1)" "unprognostic (4.04e-2)" "unprognostic (4.50e-2)" CHCHD6 "CHCM1, MGC13016, Mic25, MICOS25, PPP1R23" ENSG00000159685 "Coiled-coil-helix-coiled-coil-helix domain containing 6" Q9BRQ6 3 126704240-126960420 "Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 62.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 387.6;Late primary spermatocytes: 255.6;Melanocytes: 455.3;Oocytes: 225.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047673, HPA051975" Approved Supported Mitochondria,Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 78: Brain - Neuronal signaling" "Cluster 29: Forebrain - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 61: Schwann cells & Melanocytes - Mixed function" 30 Mitochondria Cytosol "HPA047673: , HPA051975: " "unprognostic (6.88e-2)" "unprognostic (2.99e-2)" "unprognostic (2.28e-3)" "unprognostic (2.64e-2)" "unprognostic (1.04e-1)" "unprognostic (2.52e-1)" "unprognostic (1.19e-1)" "unprognostic (1.62e-2)" "unprognostic (1.58e-1)" "unprognostic (2.72e-3)" "unprognostic (5.99e-2)" "potential prognostic unfavorable (7.47e-4)" "unprognostic (8.82e-3)" "potential prognostic unfavorable (6.92e-4)" "unprognostic (2.30e-2)" "unprognostic (6.61e-2)" "unprognostic (7.86e-2)" "unprognostic (3.70e-1)" "unprognostic (2.79e-1)" "unprognostic (9.63e-2)" "unprognostic (1.44e-3)" "unprognostic (2.00e-1)" "unprognostic (2.39e-3)" "unprognostic (1.46e-1)" "unprognostic (8.57e-3)" "unprognostic (1.91e-2)" "unprognostic (1.87e-1)" "unprognostic (2.65e-2)" "unprognostic (1.48e-1)" "unprognostic (1.55e-1)" "unprognostic (8.44e-2)" CHCHD7 "COX23, MGC2217" ENSG00000170791 "Coiled-coil-helix-coiled-coil-helix domain containing 7" Q9BUK0 8 56211686-56218809 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 313.6;Megakaryocytes: 160.7" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 46.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" HPA050783 Approved Approved "Cell Junctions,Aggresome" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 7: Non-specific - Ribosome" "Cluster 40: Non-specific - Unknown function" "Cluster 65: Non-specific - Cell growth & division" "Cell Junctions" Aggresome "HPA050783: " "unprognostic (2.51e-2)" "potential prognostic unfavorable (7.63e-4)" "unprognostic (4.53e-2)" "unprognostic (1.61e-1)" "unprognostic (2.24e-2)" "unprognostic (2.68e-2)" "unprognostic (5.51e-3)" "unprognostic (8.39e-2)" "unprognostic (4.35e-2)" "unprognostic (3.66e-2)" "unprognostic (1.26e-2)" "unprognostic (4.17e-1)" "unprognostic (2.76e-1)" "unprognostic (4.80e-2)" "unprognostic (1.20e-2)" "unprognostic (5.86e-2)" "unprognostic (3.23e-1)" "unprognostic (3.65e-2)" "unprognostic (1.34e-1)" "unprognostic (1.58e-1)" "unprognostic (1.12e-2)" "unprognostic (1.34e-2)" "potential prognostic unfavorable (1.76e-4)" "unprognostic (7.31e-2)" "unprognostic (9.53e-2)" "unprognostic (2.56e-1)" "unprognostic (1.72e-1)" "unprognostic (5.92e-2)" "unprognostic (3.60e-1)" "unprognostic (2.15e-1)" "unprognostic (3.02e-2)" CHCT1 C17orf64 ENSG00000141371 "CHD1 helical C-terminal domain containing 1" Q86WR6 17 60392429-60431426 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 219 "testis: 125.7" "Group enriched" "Detected in some" 8 "Early spermatids: 1117.4;Late primary spermatocytes: 1033.5;Late spermatids: 690.9" "Cell type enriched" "Detected in some" 6 "central nervous system macrophage: 7.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 2.5" "Group enriched" "Detected in many" 4 "dendritic cells: 2.5;granulocytes: 1.0" "Cancer enhanced" "Detected in single" "Leukemia: 1.0" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA044415 Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 6: Testis - Spermatogenesis" "Cluster 6: Non-specific - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" Nucleoplasm Vesicles "HPA044415: " CHD1 ENSG00000153922 "Chromodomain helicase DNA binding protein 1" O14646 5 98853985-98929007 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Hydrolase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 612.3;Neutrophils: 1764.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022236 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Vesicles" NA NA 3100 "Cluster 21: Neutrophils - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 25: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 15 Nucleoplasm "Nucleoli fibrillar center, Vesicles" "HPA022236: " "unprognostic (3.03e-1)" "unprognostic (1.24e-1)" "unprognostic (1.11e-2)" "unprognostic (4.97e-3)" "unprognostic (4.68e-2)" "unprognostic (5.65e-3)" "unprognostic (8.50e-2)" "unprognostic (3.85e-1)" "unprognostic (1.33e-1)" "unprognostic (3.95e-2)" "validated prognostic favorable (5.34e-5)" "validated prognostic favorable (7.21e-4)" "unprognostic (1.18e-2)" "unprognostic (1.36e-1)" "unprognostic (1.78e-1)" "unprognostic (1.43e-1)" "unprognostic (6.61e-3)" "unprognostic (1.63e-2)" "unprognostic (2.89e-1)" "unprognostic (9.03e-2)" "unprognostic (1.48e-1)" "unprognostic (1.92e-2)" "unprognostic (1.56e-2)" "unprognostic (2.36e-1)" "unprognostic (3.95e-2)" "unprognostic (5.38e-2)" "unprognostic (3.38e-1)" "unprognostic (6.13e-2)" "unprognostic (2.79e-1)" "unprognostic (5.42e-2)" "unprognostic (3.00e-1)" CHD1L ALC1 ENSG00000131778 "Chromodomain helicase DNA binding protein 1 like" Q86WJ1 1 147242654-147295765 "Predicted intracellular proteins" "DNA damage, DNA repair" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 62.1;Bergmann glia: 71.1;Brain excitatory neurons: 50.7;Brain inhibitory neurons: 48.5;Choroid plexus epithelial cells: 41.1;Distal convoluted tubule cells: 42.3;Ependymal cells: 58.1;Loop of henle epithelial cells: 32.8;Microglia: 82.4;Oligodendrocyte progenitor cells: 85.5;Oligodendrocytes: 99.3;Other brain neurons: 34.1;Podocytes: 35.9;Proximal tubule cells: 37.9;Renal collecting duct intercalated cells: 54.4;Renal collecting duct principal cells: 43.6;Renal connecting tubule cells: 40.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027789, HPA027790, HPA028670" Enhanced Enhanced Nucleoplasm NA NA "Cluster 41: Basophils - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 102: Non-specific - Mixed function" 21 Nucleoplasm "HPA027789: , HPA027790: , HPA028670: " "unprognostic (8.62e-3)" "unprognostic (2.86e-1)" "potential prognostic favorable (1.35e-5)" "unprognostic (1.19e-1)" "unprognostic (1.44e-3)" "unprognostic (1.98e-1)" "unprognostic (4.50e-2)" "unprognostic (2.42e-2)" "unprognostic (1.40e-3)" "unprognostic (2.00e-2)" "unprognostic (2.39e-3)" "unprognostic (4.52e-2)" "unprognostic (7.47e-3)" "potential prognostic unfavorable (3.65e-5)" "unprognostic (1.57e-2)" "unprognostic (1.74e-2)" "unprognostic (1.56e-2)" "unprognostic (1.63e-1)" "unprognostic (1.35e-2)" "unprognostic (5.01e-2)" "unprognostic (5.94e-2)" "unprognostic (4.92e-2)" "unprognostic (3.14e-1)" "unprognostic (1.75e-1)" "unprognostic (2.14e-2)" "unprognostic (9.72e-2)" "unprognostic (5.15e-2)" "unprognostic (1.48e-1)" "unprognostic (3.83e-1)" "unprognostic (2.95e-2)" "unprognostic (2.05e-1)" CHD2 "DKFZp547I1315, DKFZp686E01200, DKFZp781D1727, FLJ38614" ENSG00000173575 "Chromodomain helicase DNA binding protein 2" O14647 15 92886203-93027996 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Myogenesis, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Hydrolase" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial glandular cells: 1126.6;Neutrophils: 1760.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060744, HPA060960" Enhanced Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Vesicles" NA NA 24000 "Cluster 20: Non-specific - DNA binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 16: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 6 Nucleoplasm "Nucleoli, Golgi apparatus, Vesicles" "HPA060744: , HPA060960: " "unprognostic (7.71e-2)" "unprognostic (3.79e-1)" "unprognostic (2.75e-3)" "unprognostic (4.72e-2)" "unprognostic (7.66e-2)" "unprognostic (2.15e-2)" "unprognostic (2.52e-1)" "unprognostic (4.78e-2)" "unprognostic (2.70e-1)" "unprognostic (2.34e-3)" "potential prognostic favorable (8.65e-4)" "unprognostic (1.06e-3)" "unprognostic (8.80e-3)" "unprognostic (6.43e-3)" "unprognostic (1.33e-1)" "unprognostic (1.99e-2)" "unprognostic (1.05e-2)" "unprognostic (1.33e-1)" "unprognostic (1.91e-2)" "unprognostic (1.31e-1)" "unprognostic (2.88e-1)" "unprognostic (2.13e-2)" "potential prognostic unfavorable (8.06e-5)" "unprognostic (4.66e-2)" "unprognostic (9.60e-3)" "unprognostic (5.47e-2)" "unprognostic (4.70e-2)" "unprognostic (8.24e-2)" "unprognostic (4.66e-1)" "unprognostic (6.80e-2)" "unprognostic (9.80e-2)" CHD3 "Mi-2a, Mi2-ALPHA, ZFH" ENSG00000170004 "Chromodomain helicase DNA binding protein 3" Q12873 17 7884796-7912760 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Hydrolase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Prostatic glandular cells: 185.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Heart muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043368, HPA076524" Supported Supported "Nucleoplasm,Nucleoli,Centriolar satellite" No No "Cluster 30: Non-specific - DNA binding" "Cluster 75: Ovary - Mixed function" "Cluster 29: Forebrain - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 149 "Nucleoplasm, Nucleoli" "Centriolar satellite" "HPA043368: , HPA076524: " "unprognostic (2.60e-3)" "unprognostic (4.59e-3)" "unprognostic (5.38e-2)" "unprognostic (3.10e-2)" "unprognostic (6.08e-2)" "unprognostic (9.33e-2)" "unprognostic (5.41e-1)" "unprognostic (2.82e-3)" "unprognostic (4.93e-3)" "unprognostic (7.87e-2)" "unprognostic (5.94e-2)" "unprognostic (3.29e-2)" "unprognostic (1.99e-1)" "unprognostic (1.14e-1)" "unprognostic (2.67e-1)" "unprognostic (2.07e-2)" "unprognostic (1.38e-1)" "unprognostic (6.84e-2)" "unprognostic (1.75e-1)" "unprognostic (8.16e-3)" "unprognostic (1.58e-3)" "unprognostic (2.92e-3)" "unprognostic (1.59e-2)" "unprognostic (2.62e-1)" "unprognostic (2.63e-1)" "unprognostic (3.55e-1)" "unprognostic (3.55e-3)" "unprognostic (1.26e-2)" "unprognostic (3.32e-1)" "unprognostic (8.36e-3)" "unprognostic (1.21e-2)" CHD4 "Mi-2b, Mi2-BETA" ENSG00000111642 "Chromodomain helicase DNA binding protein 4" Q14839 12 6570082-6614524 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Hydrolase" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 83.4;Bergmann glia: 74.8;Choroid plexus epithelial cells: 64.4;Ependymal cells: 70.0;Microglia: 63.1;Oligodendrocytes: 77.9;Other brain neurons: 56.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012008 Supported Enhanced "Nucleoplasm,Mitotic spindle,Cytosol" Yes NA 32000 "Cluster 30: Non-specific - DNA binding" "Cluster 80: Thymus - Adaptive immune response" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 22: Non-specific - Basic cellular functions" 221 Nucleoplasm "Mitotic spindle, Cytosol" "HPA012008: " "unprognostic (2.29e-1)" "unprognostic (3.56e-2)" "unprognostic (4.35e-1)" "unprognostic (6.08e-2)" "unprognostic (2.05e-1)" "unprognostic (2.70e-1)" "unprognostic (3.03e-2)" "potential prognostic favorable (5.12e-5)" "unprognostic (1.15e-2)" "unprognostic (5.62e-3)" "potential prognostic favorable (1.43e-4)" "unprognostic (5.72e-3)" "unprognostic (3.57e-1)" "unprognostic (4.12e-3)" "unprognostic (1.81e-1)" "unprognostic (1.64e-1)" "unprognostic (8.98e-2)" "unprognostic (4.69e-2)" "unprognostic (1.85e-1)" "unprognostic (8.56e-3)" "unprognostic (4.44e-1)" "unprognostic (3.23e-1)" "unprognostic (4.83e-3)" "unprognostic (1.16e-2)" "unprognostic (3.49e-1)" "unprognostic (9.90e-2)" "unprognostic (3.44e-2)" "unprognostic (1.71e-1)" "unprognostic (9.60e-2)" "unprognostic (1.39e-1)" "unprognostic (4.23e-2)" CHD5 ENSG00000116254 "Chromodomain helicase DNA binding protein 5" Q8TDI0 1 6101787-6180321 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Differentiation, Neurogenesis, Spermatogenesis, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Hydrolase" "Disease variant, Epilepsy, Intellectual disability, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 80.2;pituitary gland: 53.4;testis: 30.9" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 78.7;Brain inhibitory neurons: 62.9;Early spermatids: 245.1;Lactotrophs: 169.5;Late primary spermatocytes: 63.7;Late spermatids: 134.3;Other brain neurons: 73.2;Retinal amacrine cells: 111.3;Retinal ganglion cells: 50.2;Retinal horizontal cells: 122.2;Somatotrophs: 229.4;Thyrotrophs: 210.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 1.7;Kidney Chromophobe (TCGA): 1.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 5.9" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Lung - Smooth muscle cells, Pancreas - Alpha cells, Prostate - Smooth muscle cells, Skin - Smooth muscle cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015809 Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 18 "Nucleoplasm, Nuclear speckles" Cytosol "HPA015809: " "unprognostic (6.35e-2)" "potential prognostic favorable (1.05e-4)" "unprognostic (9.20e-3)" CHD6 "CHD5, dJ620E11.1, FLJ22369, KIAA1335, RIGB" ENSG00000124177 "Chromodomain helicase DNA binding protein 6" Q8TD26 20 41402083-41618384 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 7 "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 99.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015543 Supported Nucleoplasm NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 61: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 7: Non-specific - Transcription" 1 Nucleoplasm "HPA015543: " "unprognostic (7.91e-2)" "unprognostic (1.20e-2)" "unprognostic (1.13e-1)" "unprognostic (1.42e-1)" "unprognostic (2.00e-1)" "unprognostic (1.21e-1)" "unprognostic (8.64e-2)" "unprognostic (5.85e-3)" "unprognostic (1.34e-1)" "unprognostic (7.72e-2)" "validated prognostic favorable (2.08e-5)" "validated prognostic favorable (3.78e-5)" "unprognostic (3.02e-1)" "unprognostic (7.41e-3)" "unprognostic (2.53e-2)" "unprognostic (5.04e-3)" "unprognostic (1.06e-1)" "unprognostic (6.45e-2)" "unprognostic (7.10e-2)" "unprognostic (1.57e-1)" "unprognostic (9.78e-2)" "unprognostic (2.01e-1)" "unprognostic (4.54e-2)" "unprognostic (1.24e-1)" "unprognostic (2.71e-3)" "unprognostic (2.34e-2)" "unprognostic (1.78e-1)" "unprognostic (5.31e-2)" "unprognostic (1.70e-1)" "unprognostic (6.18e-2)" "unprognostic (1.55e-1)" CHD7 "CRG, FLJ20357, FLJ20361, KIAA1416" ENSG00000171316 "Chromodomain helicase DNA binding protein 7" Q9P2D1 8 60678740-60868028 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "rRNA processing, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Hydrolase" "Cancer-related genes, Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.5" "Cell type enhanced" "Detected in many" "Corticotrophs: 373.1;Microglia: 384.4;Neutrophil progenitors: 458.2;Neutrophils: 491.3;Oligodendrocyte progenitor cells: 483.9;Oligodendrocytes: 392.4" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 470.6;oligodendrocyte precursor cell: 573.4;upper rhombic lip: 607.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 15 "B-cells: 14.1;granulocytes: 15.2;T-cells: 5.5" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells, Spleen - B-cells (Spleen), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 119.9" HPA053075 Supported Nucleoplasm,Nucleoli NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 27: Cerebellum - Synaptic function" "Cluster 25: Non-specific - Transcription" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 19 Nucleoplasm Nucleoli "HPA053075: " "unprognostic (3.94e-2)" "unprognostic (1.41e-2)" "unprognostic (1.44e-2)" "potential prognostic unfavorable (9.55e-4)" "unprognostic (2.85e-1)" "unprognostic (1.64e-1)" "unprognostic (5.46e-2)" "potential prognostic favorable (1.93e-4)" "unprognostic (2.71e-2)" "unprognostic (9.10e-2)" "unprognostic (1.42e-1)" "unprognostic (1.09e-1)" "unprognostic (2.37e-1)" "potential prognostic unfavorable (3.47e-4)" "unprognostic (1.19e-1)" "unprognostic (1.40e-1)" "unprognostic (2.22e-1)" "unprognostic (3.25e-1)" "unprognostic (2.56e-1)" "unprognostic (2.82e-1)" "unprognostic (2.46e-1)" "unprognostic (1.91e-1)" "unprognostic (3.97e-2)" "unprognostic (1.11e-1)" "unprognostic (2.96e-2)" "unprognostic (1.76e-1)" "unprognostic (3.29e-1)" "unprognostic (5.55e-2)" "unprognostic (1.55e-1)" "unprognostic (7.11e-2)" "unprognostic (3.85e-2)" CHD8 "DUPLIN, HELSNF1, KIAA1564" ENSG00000100888 "Chromodomain helicase DNA binding protein 8" Q9HCK8 14 21385194-21456126 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, Chromatin regulator, DNA-binding, Hydrolase, Repressor" "Autism, Autism spectrum disorder, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052186, HPA076133" Supported "Nucleoplasm,Plasma membrane,Primary cilium,Primary cilium tip" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 49: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 7: Non-specific - Transcription" 62 Nucleoplasm "Plasma membrane, Primary cilium, Primary cilium tip" "HPA052186: , HPA076133: " "unprognostic (1.04e-2)" "unprognostic (2.93e-1)" "unprognostic (1.11e-1)" "unprognostic (2.17e-2)" "unprognostic (7.20e-2)" "unprognostic (5.77e-2)" "unprognostic (1.44e-1)" "unprognostic (1.16e-3)" "unprognostic (1.49e-1)" "unprognostic (3.97e-3)" "potential prognostic favorable (6.04e-5)" "unprognostic (6.48e-3)" "unprognostic (7.25e-2)" "potential prognostic unfavorable (3.74e-4)" "unprognostic (4.45e-2)" "unprognostic (1.73e-1)" "unprognostic (5.13e-2)" "unprognostic (1.29e-1)" "unprognostic (4.27e-2)" "unprognostic (1.97e-2)" "unprognostic (2.63e-3)" "unprognostic (3.90e-1)" "unprognostic (9.02e-2)" "unprognostic (4.09e-1)" "unprognostic (1.85e-1)" "unprognostic (3.74e-1)" "unprognostic (7.86e-2)" "unprognostic (1.30e-1)" "unprognostic (4.34e-2)" "unprognostic (1.39e-1)" "unprognostic (1.37e-2)" CHD9 "BC022889, FLJ12178, KIAA0308" ENSG00000177200 "Chromodomain helicase DNA binding protein 9" Q3L8U1 16 53054991-53329150 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042053, HPA049420, HPA066155" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 25: Non-specific - Transcription" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Transcription" 3 Nucleoplasm Cytosol "HPA042053: , HPA049420: , HPA066155: " "unprognostic (1.96e-2)" "unprognostic (9.59e-2)" "unprognostic (2.65e-1)" "potential prognostic unfavorable (5.39e-4)" "unprognostic (3.38e-1)" "unprognostic (6.57e-2)" "unprognostic (7.46e-2)" "unprognostic (2.33e-2)" "unprognostic (8.37e-2)" "unprognostic (4.07e-3)" "potential prognostic favorable (7.80e-7)" "unprognostic (4.79e-3)" "unprognostic (1.86e-1)" "unprognostic (3.38e-1)" "unprognostic (1.49e-3)" "unprognostic (5.07e-2)" "unprognostic (2.52e-1)" "unprognostic (1.17e-1)" "unprognostic (3.75e-1)" "unprognostic (1.40e-1)" "unprognostic (1.64e-2)" "unprognostic (8.83e-2)" "unprognostic (2.46e-2)" "unprognostic (2.39e-1)" "unprognostic (1.08e-2)" "unprognostic (5.58e-2)" "unprognostic (2.81e-2)" "unprognostic (4.06e-2)" "unprognostic (3.77e-1)" "unprognostic (1.12e-2)" "unprognostic (3.75e-1)" CHDH ENSG00000016391 "Choline dehydrogenase" Q8NE62 3 53812335-53846419 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 35.1;liver: 33.2" "Cell type enhanced" "Detected in many" "Bergmann glia: 64.1;Enteric stem cells: 69.7;Enterocytes: 66.8;Hepatocytes: 68.2;Late spermatids: 76.2;Paneth cells: 65.7;Proximal tubule cells: 132.8;Tuft cells: 138.3" "Cell type enhanced" "Detected in many" "Bergmann glia: 80.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 14 "basophil: 3.0;T-reg: 1.3" "Group enriched" "Detected in many" 18 "granulocytes: 3.0;T-cells: 1.3" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Minor Salivary Gland - Smooth muscle cells, Skin - Eccrine sweat gland cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA036632, HPA036633, HPA058130" Enhanced Approved Nucleoli,Mitochondria NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 72: Kidney - Transmembrane transport" "Cluster 19: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 95: Tuft cells - Chemosensory signaling" 4 Mitochondria Nucleoli "HPA036632: , HPA036633: , HPA058130: " "unprognostic (1.02e-3)" "unprognostic (6.63e-2)" "unprognostic (3.54e-2)" "unprognostic (8.42e-2)" "unprognostic (8.17e-3)" "unprognostic (6.09e-2)" "unprognostic (2.77e-1)" "unprognostic (4.02e-2)" "unprognostic (3.49e-1)" "validated prognostic favorable (2.64e-8)" "validated prognostic favorable (2.91e-4)" "potential prognostic favorable (1.39e-4)" "unprognostic (1.64e-1)" "unprognostic (1.68e-2)" "unprognostic (1.12e-2)" "unprognostic (2.10e-2)" "unprognostic (2.06e-1)" "unprognostic (3.36e-1)" "unprognostic (2.62e-2)" "unprognostic (2.94e-1)" "unprognostic (4.47e-2)" "unprognostic (6.92e-2)" "unprognostic (5.64e-2)" "unprognostic (1.50e-2)" "unprognostic (1.20e-1)" "unprognostic (8.82e-3)" "unprognostic (1.59e-1)" "unprognostic (2.31e-1)" "unprognostic (9.11e-2)" CHEK1 CHK1 ENSG00000149554 "Checkpoint kinase 1" O14757 11 125625163-125676255 "Cancer-related genes, Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 24.9;lymphoid tissue: 19.5;seminal vesicle: 28.7" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 65.4;Early primary spermatocytes: 87.2;Epididymal basal cells: 91.9;Erythrocyte progenitors: 99.8;Extravillous trophoblasts: 47.2;Megakaryocyte progenitors: 87.2;Megakaryocyte-Erythroid progenitors: 47.2;Monocyte progenitors: 74.3;Oocytes: 142.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 6.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" HPA044364 Supported Nucleoplasm,Vesicles NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 31: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 77 Nucleoplasm Vesicles "HPA044364: " "unprognostic (6.33e-2)" "unprognostic (2.09e-2)" "unprognostic (1.01e-1)" "unprognostic (6.87e-2)" "unprognostic (3.77e-2)" "unprognostic (8.50e-2)" "unprognostic (2.46e-1)" "unprognostic (2.58e-2)" "unprognostic (2.66e-1)" "unprognostic (2.92e-3)" "validated prognostic unfavorable (4.40e-4)" "validated prognostic unfavorable (3.61e-5)" "unprognostic (9.23e-3)" "validated prognostic unfavorable (7.24e-8)" "validated prognostic unfavorable (6.72e-4)" "potential prognostic unfavorable (5.92e-5)" "unprognostic (1.79e-3)" "unprognostic (9.48e-3)" "unprognostic (6.49e-2)" "unprognostic (1.24e-1)" "unprognostic (1.14e-1)" "potential prognostic unfavorable (2.38e-7)" "unprognostic (6.41e-3)" "unprognostic (1.88e-2)" "unprognostic (2.64e-3)" "unprognostic (1.95e-1)" "unprognostic (1.55e-3)" "unprognostic (2.15e-2)" "unprognostic (1.90e-2)" "unprognostic (2.57e-1)" "unprognostic (1.28e-1)" CHEK2 "bA444G7, CDS1, CHK2, HuCds1, PP1425, RAD53" ENSG00000183765 "Checkpoint kinase 2" O96017 22 28687743-28742422 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell cycle, Cell division, DNA damage, DNA repair, Host-virus interaction, Mitosis, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Li-Fraumeni syndrome, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 68.3;Megakaryocyte progenitors: 46.7;Monocyte progenitors: 42.4" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 36.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001878, CAB002030" Enhanced Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 66: Non-specific - Mitochondria" "Cluster 27: Non-specific - Cell proliferation" 85 Nucleoplasm "Golgi apparatus" "CAB002030: , HPA001878: " "unprognostic (6.83e-2)" "unprognostic (7.92e-2)" "unprognostic (9.93e-2)" "unprognostic (1.74e-1)" "unprognostic (1.81e-1)" "unprognostic (1.67e-1)" "unprognostic (6.07e-2)" "unprognostic (1.13e-1)" "unprognostic (1.43e-1)" "potential prognostic unfavorable (4.24e-4)" "validated prognostic unfavorable (1.01e-7)" "validated prognostic unfavorable (6.88e-4)" "unprognostic (7.43e-2)" "potential prognostic unfavorable (7.64e-4)" "unprognostic (3.98e-2)" "unprognostic (4.82e-2)" "unprognostic (2.77e-2)" "potential prognostic favorable (3.68e-7)" "unprognostic (8.94e-3)" "unprognostic (5.36e-2)" "unprognostic (3.79e-1)" "unprognostic (3.00e-2)" "unprognostic (1.61e-3)" "unprognostic (3.48e-2)" "unprognostic (1.23e-3)" "unprognostic (1.34e-1)" "unprognostic (4.72e-2)" "unprognostic (4.41e-2)" "unprognostic (1.17e-1)" "unprognostic (1.28e-1)" "unprognostic (6.94e-2)" CHERP "DAN16, ERPROT213-21" ENSG00000085872 "Calcium homeostasis endoplasmic reticulum protein" Q8IWX8 19 16517894-16542437 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 2.6;Cardiomyocytes: 3.0;Epicardial cells: 6.8;Erythrocyte progenitors: 1.7;Lacrimal acinar cells: 2.7;Respiratory deuterosomal cells: 2.1;Retinal horizontal cells: 2.0" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 24: Non-specific - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 89 "unprognostic (8.75e-2)" "unprognostic (1.47e-1)" "unprognostic (2.67e-1)" "unprognostic (3.21e-1)" "unprognostic (1.52e-1)" "unprognostic (8.62e-2)" "unprognostic (3.27e-1)" "unprognostic (8.99e-2)" "unprognostic (4.95e-2)" "unprognostic (2.27e-2)" "unprognostic (1.55e-2)" "unprognostic (7.33e-2)" "unprognostic (6.11e-2)" "unprognostic (1.49e-2)" "unprognostic (2.46e-1)" "unprognostic (4.79e-2)" "unprognostic (1.74e-1)" "unprognostic (1.72e-1)" "unprognostic (2.15e-2)" "unprognostic (2.39e-1)" "unprognostic (6.18e-2)" "unprognostic (4.38e-2)" "unprognostic (3.69e-3)" "unprognostic (4.44e-3)" "unprognostic (7.27e-3)" "unprognostic (3.80e-3)" "unprognostic (5.26e-2)" "unprognostic (2.82e-2)" "unprognostic (4.59e-2)" "unprognostic (7.01e-2)" "unprognostic (2.66e-2)" CHFR "FLJ10796, RNF196" ENSG00000072609 "Checkpoint with forkhead and ring finger domains" Q96EP1 12 132822187-132956304 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 191.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045768, HPA073826" Approved Uncertain "Nuclear bodies,Microtubules" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 29 "Nuclear bodies, Microtubules" "HPA045768: , HPA073826: " "unprognostic (2.55e-3)" "unprognostic (6.23e-2)" "unprognostic (4.06e-2)" "unprognostic (1.20e-1)" "unprognostic (8.24e-2)" "unprognostic (6.61e-3)" "unprognostic (1.61e-1)" "unprognostic (4.31e-3)" "unprognostic (5.56e-3)" "unprognostic (1.36e-1)" "unprognostic (1.20e-2)" "unprognostic (1.89e-3)" "unprognostic (6.23e-2)" "potential prognostic unfavorable (3.37e-4)" "unprognostic (2.52e-1)" "unprognostic (1.67e-2)" "unprognostic (3.75e-2)" "unprognostic (4.28e-2)" "unprognostic (2.78e-1)" "unprognostic (1.99e-1)" "unprognostic (2.34e-1)" "unprognostic (2.75e-1)" "unprognostic (1.65e-3)" "unprognostic (9.33e-2)" "unprognostic (6.14e-2)" "unprognostic (1.65e-1)" "unprognostic (2.93e-2)" "unprognostic (1.33e-1)" "unprognostic (1.46e-1)" "unprognostic (1.05e-1)" "unprognostic (3.06e-2)" CHGA "PHE5, PHES" ENSG00000100604 "Chromogranin A" P10645 14 92923150-92935285 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins" "Antibiotic, Antimicrobial, Fungicide" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "parathyroid gland: 6179.1" "Cell type enriched" "Detected in some" 5 "Neuroendocrine cells: 599.2" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Pancreatic Adenocarcinoma (TCGA): 231.4;Uterine Corpus Endometrial Carcinoma (TCGA): 183.2" "Group enriched" "Detected in all" 6 "cerebral cortex: 857.5;white matter: 400.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "Neuroblastoma: 570.3" "Adrenal gland - Adrenal medulla cells, Pancreas - Alpha cells, Pituitary gland - Thyrotropes, Stomach - Gastric enteroendocrine cells, Testis - Sertoli cells, Thyroid gland - Parafollicular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000023, HPA017369, CAB040544, CAB055506, CAB058688" Enhanced Approved Vesicles "Intracellular and membrane" Defense NA NA 64000000 "Cluster 69: Parathyroid gland - Mixed function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" Vesicles "CAB000023: , CAB040544: , CAB055506: , CAB058688: , HPA017369: " "potential prognostic unfavorable (1.37e-4)" "unprognostic (1.49e-3)" "unprognostic (1.69e-1)" "unprognostic (8.75e-2)" "unprognostic (6.98e-2)" "unprognostic (2.03e-1)" "unprognostic (1.52e-2)" "unprognostic (1.34e-2)" "unprognostic (1.15e-1)" "potential prognostic unfavorable (1.05e-6)" "potential prognostic unfavorable (1.71e-4)" "unprognostic (5.86e-2)" "unprognostic (8.32e-2)" "unprognostic (2.37e-1)" "unprognostic (4.33e-1)" "unprognostic (8.75e-2)" "unprognostic (1.20e-2)" "potential prognostic favorable (4.35e-4)" "unprognostic (3.88e-1)" "unprognostic (1.33e-1)" "unprognostic (1.14e-1)" "unprognostic (3.00e-2)" "unprognostic (4.69e-3)" "unprognostic (1.74e-1)" "unprognostic (1.07e-2)" CHGB "SCG1, SgI" ENSG00000089199 "Chromogranin B" P05060 20 5911510-5925353 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 3273.4;brain: 663.8;pituitary gland: 1393.2" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 2903.9;Gonadotrophs: 4712.6;Lactotrophs: 956.9;Neuroendocrine cells: 1086.9;Pancreatic islet cells: 3423.3;Somatotrophs: 936.5" "Cell type enhanced" "Detected in all" "upper rhombic lip: 434.7" "Cancer enriched" "Detected in many" 5 "Pancreatic Adenocarcinoma (TCGA): 398.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Gastric cancer: 77.4;lung cancer: 63.1;Neuroblastoma: 230.8;thyroid cancer: 195.7" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Kidney - Ascending Loop of Henle cells, Pancreas - Alpha cells, Stomach - Gastric enteroendocrine cells, Testis - Spermatocytes, Thyroid gland - Parafollicular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008759, CAB009403, HPA012602" Enhanced Supported Enhanced Vesicles "Intracellular and membrane" "No annotated function" NA NA 9600000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 4 Vesicles "CAB009403: , HPA008759: , HPA012602: " "unprognostic (4.53e-2)" "unprognostic (8.06e-3)" "unprognostic (1.51e-1)" "unprognostic (2.41e-1)" "unprognostic (3.43e-1)" "unprognostic (1.80e-1)" "unprognostic (4.75e-2)" "unprognostic (1.62e-2)" "potential prognostic unfavorable (1.92e-4)" "unprognostic (2.09e-1)" "unprognostic (1.24e-1)" "unprognostic (2.82e-2)" "unprognostic (2.37e-2)" "unprognostic (2.44e-1)" "unprognostic (1.87e-1)" "unprognostic (9.46e-2)" "unprognostic (3.01e-1)" "unprognostic (1.28e-1)" "unprognostic (1.12e-1)" "potential prognostic favorable (3.94e-4)" "unprognostic (1.58e-2)" "unprognostic (3.64e-2)" "unprognostic (3.91e-1)" "unprognostic (4.19e-2)" "unprognostic (1.04e-2)" "unprognostic (9.21e-2)" "unprognostic (2.37e-2)" "unprognostic (2.77e-1)" "unprognostic (1.04e-2)" CHI3L1 "GP39, YK-40, YKL40" ENSG00000133048 "Chitinase 3 like 1" P36222 1 203178931-203186704 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Inflammatory response" Antimicrobial "Asthma, Cancer-related genes, Schizophrenia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 347.9;liver: 423.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 106.2;Breast secretory cells: 127.5;Decidual stromal cells: 95.7;Endometrial secretory cells: 202.9;Fallopian secretory cells: 79.8;Mesothelial cells: 83.1;Müller glia: 47.2;Neutrophil progenitors: 161.2;Pituicytes/FSCs: 75.4;Podocytes: 152.5;Salivary myoepithelial cells: 80.1" "Cell type enhanced" "Detected in some" "astrocyte: 49.0;central nervous system macrophage: 13.5" "Cancer enriched" "Detected in all" 10 "Glioblastoma Multiforme (TCGA): 4051.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 494 "neutrophil: 472.1" "Lineage enriched" "Detected in single" 494 "granulocytes: 472.1" "Group enriched" "Detected in many" 4 "Bile duct cancer: 271.9;Brain cancer: 202.6" "Kidney - Podocytes, Minor Salivary Gland - Minor salivary glandular cells, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 6 "olfactory bulb: 28.3" HPA077365 Approved "Golgi apparatus,Vesicles" "Secreted to blood" Defense NA NA 25100000 48000000 "Cluster 4: Neutrophils - Degranulation" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 12: Non-specific - Vasculature" "Cluster 72: Neuronal - Signal transduction" "Cluster 108: Fibroblasts - ECM organization" 7 "Golgi apparatus" Vesicles "HPA077365: " "unprognostic (2.87e-2)" "unprognostic (2.59e-3)" "unprognostic (6.10e-2)" "unprognostic (7.78e-2)" "unprognostic (1.20e-1)" "unprognostic (3.83e-1)" "unprognostic (8.12e-3)" "unprognostic (1.51e-3)" "unprognostic (1.46e-1)" "unprognostic (1.49e-2)" "unprognostic (1.02e-1)" "unprognostic (1.88e-2)" "unprognostic (1.40e-1)" "unprognostic (2.86e-1)" "unprognostic (5.08e-2)" "unprognostic (3.77e-2)" "unprognostic (2.48e-1)" "unprognostic (8.72e-3)" "unprognostic (1.43e-1)" "unprognostic (2.29e-1)" "unprognostic (2.37e-1)" "unprognostic (5.74e-2)" "unprognostic (1.62e-3)" "unprognostic (8.24e-2)" "unprognostic (2.82e-1)" "unprognostic (8.47e-2)" "unprognostic (1.01e-3)" "unprognostic (2.15e-2)" "unprognostic (3.75e-2)" "unprognostic (1.29e-2)" "unprognostic (6.09e-2)" CHI3L2 "YKL-39, YKL39" ENSG00000064886 "Chitinase 3 like 2" Q15782 1 111200771-111243440 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 186.8;salivary gland: 133.9" "Group enriched" "Detected in many" 6 "Lacrimal acinar cells: 596.9;Salivary acinar cells: 571.1" "Group enriched" "Detected in some" 4 "astrocyte: 3.0;central nervous system macrophage: 1.6;leukocyte: 5.1" "Cancer enriched" "Detected in many" 8 "Glioblastoma Multiforme (TCGA): 399.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 91.9" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Leukemia: 153.8;lymphoma: 103.9" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" HPA005443 Approved "Secreted to blood" Enzyme NA NA 540000 "Cluster 24: Non-specific - Transcription" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 59: Leukemia - T-cell receptor" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 3 "HPA005443: " "unprognostic (8.29e-2)" "unprognostic (1.42e-2)" "unprognostic (1.30e-1)" "unprognostic (9.38e-3)" "unprognostic (2.65e-1)" "unprognostic (2.39e-1)" "potential prognostic unfavorable (6.99e-4)" "unprognostic (2.50e-2)" "unprognostic (3.20e-3)" "potential prognostic unfavorable (1.38e-5)" "unprognostic (3.00e-2)" "unprognostic (2.68e-1)" "unprognostic (3.53e-1)" "unprognostic (1.44e-2)" "unprognostic (2.46e-1)" "unprognostic (4.37e-3)" "unprognostic (1.08e-2)" "unprognostic (3.40e-1)" "unprognostic (8.52e-2)" "unprognostic (1.74e-2)" "unprognostic (7.87e-3)" "unprognostic (2.53e-2)" "unprognostic (9.55e-2)" "unprognostic (3.33e-1)" "potential prognostic unfavorable (4.50e-5)" "unprognostic (2.73e-2)" "unprognostic (2.89e-2)" "unprognostic (1.86e-2)" "unprognostic (1.13e-1)" CHIA "AMCase, CHIT2, TSA1902" ENSG00000134216 "Chitinase acidic" Q9BZP6 1 111290851-111320566 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Carbohydrate metabolism, Chitin degradation, Immunity, Inflammatory response, Polysaccharide degradation" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 34 "stomach 1: 339.8" "Group enriched" "Detected in some" 33 "Gastric chief cells: 740.4;Parietal cells: 551.6" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Lung Adenocarcinoma (TCGA): 18.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Alveolar cells type 2, Pituitary gland - Corticotropes, Stomach - Chief cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA059193 Approved "Intracellular and membrane" Immunity NA NA "Cluster 60: Stomach - Digestion" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 97: Non-specific - Cellular respiration" 3 "HPA059193: " "unprognostic (3.77e-1)" "potential prognostic favorable (3.35e-4)" "unprognostic (2.21e-2)" "unprognostic (1.39e-2)" "unprognostic (4.17e-1)" "unprognostic (1.03e-1)" "unprognostic (3.17e-2)" "unprognostic (2.10e-2)" CHIC1 BRX ENSG00000204116 "Cysteine rich hydrophobic domain 1" Q5VXU3 X 73563197-73687111 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Lactotrophs: 134.4;Somatotrophs: 146.1;Thyrotrophs: 142.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026782, HPA052062" Uncertain Approved "Nuclear speckles,Vesicles,Cytosol" NA NA "Cluster 65: Brain - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" "Nuclear speckles, Vesicles" Cytosol "HPA026782: , HPA052062: " "unprognostic (1.89e-2)" "unprognostic (2.01e-2)" "unprognostic (7.99e-2)" "unprognostic (1.27e-1)" "unprognostic (1.88e-1)" "unprognostic (3.04e-2)" "unprognostic (1.62e-1)" "unprognostic (2.38e-1)" "unprognostic (1.12e-1)" "unprognostic (3.15e-2)" "potential prognostic favorable (3.10e-6)" "unprognostic (1.85e-2)" "unprognostic (1.35e-1)" "unprognostic (1.34e-2)" "unprognostic (4.23e-1)" "unprognostic (3.76e-2)" "unprognostic (3.86e-2)" "unprognostic (1.77e-1)" "unprognostic (6.86e-2)" "unprognostic (3.38e-2)" "unprognostic (2.03e-3)" "unprognostic (3.86e-2)" "unprognostic (2.60e-1)" "unprognostic (1.30e-1)" "unprognostic (2.43e-3)" "unprognostic (1.91e-1)" "unprognostic (4.56e-3)" "unprognostic (3.70e-1)" "unprognostic (3.82e-1)" "unprognostic (2.25e-3)" CHIC2 BTL ENSG00000109220 "Cysteine rich hydrophobic domain 2" Q9UKJ5 4 54009789-54064605 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 393.5;Neutrophils: 630.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Lineage enriched" "Detected in all" 4 "granulocytes: 366.4" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026782, HPA026784, HPA076603" Uncertain Enhanced "Vesicles,Plasma membrane" NA Yes "Cluster 35: Neutrophils - Protein binding" "Cluster 39: Testis - Nuclear processes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 53 "Vesicles, Plasma membrane" "HPA026782: , HPA026784: , HPA076603: " "unprognostic (3.50e-1)" "unprognostic (1.62e-1)" "unprognostic (1.95e-2)" "unprognostic (1.34e-2)" "unprognostic (9.48e-2)" "unprognostic (3.30e-2)" "unprognostic (1.87e-1)" "unprognostic (1.37e-2)" "unprognostic (7.23e-3)" "unprognostic (1.25e-2)" "unprognostic (1.53e-3)" "potential prognostic favorable (3.34e-4)" "unprognostic (5.18e-2)" "unprognostic (2.72e-3)" "unprognostic (5.89e-2)" "unprognostic (1.39e-1)" "unprognostic (7.08e-2)" "unprognostic (3.18e-1)" "unprognostic (7.55e-2)" "unprognostic (1.45e-1)" "unprognostic (9.37e-2)" "unprognostic (5.60e-3)" "unprognostic (1.09e-2)" "unprognostic (2.25e-1)" "unprognostic (1.38e-2)" "unprognostic (3.10e-1)" "unprognostic (4.67e-2)" "unprognostic (1.67e-2)" "unprognostic (2.15e-1)" "unprognostic (8.61e-2)" "unprognostic (2.56e-1)" CHID1 "FLJ42707, MGC3234, SI-CLP" ENSG00000177830 "Chitinase domain containing 1" Q9BWS9 11 867859-915058 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early primary spermatocytes: 251.8;Epididymal principal cells: 254.9;Late spermatids: 722.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adrenal gland - Adrenal cortex cells, Kidney - Fibroblasts, Minor Salivary Gland - Minor salivary glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039374 Uncertain Uncertain "Nucleoplasm,Intermediate filaments" "Intracellular and membrane" Immunity No No 660000 "Cluster 13: Non-specific - Mitochondria" "Cluster 70: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 1 "Nucleoplasm, Intermediate filaments" "HPA039374: " "unprognostic (8.10e-2)" "unprognostic (1.41e-1)" "unprognostic (1.91e-1)" "unprognostic (7.20e-2)" "unprognostic (9.59e-2)" "unprognostic (1.18e-1)" "potential prognostic unfavorable (7.24e-4)" "unprognostic (1.17e-2)" "unprognostic (1.22e-1)" "unprognostic (1.15e-2)" "unprognostic (1.28e-3)" "unprognostic (1.08e-2)" "unprognostic (2.80e-3)" "unprognostic (8.73e-2)" "unprognostic (6.00e-2)" "unprognostic (7.06e-2)" "unprognostic (5.10e-2)" "unprognostic (1.95e-3)" "unprognostic (1.96e-1)" "unprognostic (2.04e-1)" "unprognostic (5.11e-2)" "potential prognostic favorable (6.71e-4)" "unprognostic (2.81e-1)" "unprognostic (2.60e-2)" "unprognostic (1.67e-1)" "unprognostic (5.70e-2)" "unprognostic (9.21e-2)" "unprognostic (4.35e-2)" "unprognostic (1.12e-1)" "unprognostic (6.35e-2)" "unprognostic (2.77e-1)" CHIT1 "CHI3, CHIT" ENSG00000133063 "Chitinase 1" Q13231 1 203212827-203273641 "Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Carbohydrate metabolism, Chitin degradation, Polysaccharide degradation" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 47.0;lung: 34.3;lymphoid tissue: 20.4" "Group enriched" "Detected in some" 9 "Macrophages: 146.0;Neutrophil progenitors: 257.0;Neutrophils: 65.7" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 132.8" "Region enhanced" "Detected in some" "white matter: 4.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA010575, HPA074844" Enhanced "Secreted to blood" Enzyme NA NA 26400000 10000000 "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 30: White matter - Myelination" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 1 "HPA010575: , HPA074844: " "unprognostic (5.40e-2)" "unprognostic (4.40e-2)" "unprognostic (2.14e-1)" "unprognostic (3.80e-3)" "unprognostic (4.68e-2)" "unprognostic (9.90e-2)" "unprognostic (1.44e-2)" "unprognostic (1.01e-1)" "unprognostic (1.15e-2)" "unprognostic (5.80e-2)" "unprognostic (2.96e-2)" "unprognostic (1.81e-1)" "potential prognostic favorable (9.81e-5)" "unprognostic (7.17e-2)" "unprognostic (2.00e-1)" "unprognostic (2.46e-3)" "unprognostic (2.76e-2)" "unprognostic (1.59e-1)" "unprognostic (2.03e-2)" "unprognostic (1.69e-2)" "unprognostic (6.32e-2)" "unprognostic (1.31e-1)" "unprognostic (2.01e-1)" "unprognostic (4.83e-2)" "unprognostic (2.56e-2)" "unprognostic (2.51e-1)" "unprognostic (1.49e-1)" "unprognostic (1.28e-1)" "unprognostic (6.83e-2)" "unprognostic (4.77e-2)" CHKA "CHK, CKI" ENSG00000110721 "Choline kinase alpha" P35790 11 68052859-68121444 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Kinase, Transferase, Tyrosine-protein kinase" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 6.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024153, CAB072803" Approved Approved "Endoplasmic reticulum" NA Yes "Cluster 45: Eosinophils - Unknown function" "Cluster 21: Testis - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 2 "Endoplasmic reticulum" "CAB072803: , HPA024153: " "unprognostic (9.80e-2)" "unprognostic (1.08e-2)" "unprognostic (8.94e-2)" "unprognostic (1.57e-1)" "unprognostic (6.22e-2)" "unprognostic (2.44e-1)" "unprognostic (3.04e-1)" "unprognostic (2.54e-2)" "unprognostic (7.69e-2)" "unprognostic (4.98e-2)" "unprognostic (1.28e-2)" "unprognostic (5.46e-2)" "unprognostic (1.11e-1)" "potential prognostic unfavorable (6.58e-5)" "unprognostic (7.95e-3)" "unprognostic (3.00e-2)" "unprognostic (1.61e-1)" "unprognostic (1.72e-1)" "unprognostic (9.90e-3)" "unprognostic (1.28e-2)" "unprognostic (6.78e-2)" "unprognostic (2.02e-1)" "unprognostic (6.52e-2)" "unprognostic (2.23e-1)" "unprognostic (2.42e-1)" "unprognostic (5.74e-2)" "unprognostic (3.16e-2)" "unprognostic (9.37e-2)" "unprognostic (1.49e-1)" "unprognostic (1.48e-1)" "unprognostic (2.23e-1)" CHKB "CHETK, CHKL" ENSG00000100288 "Choline kinase beta" Q9Y259 22 50578959-50601455 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Kinase, Transferase" "Congenital muscular dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 37.0;Bergmann glia: 48.0;Brain excitatory neurons: 39.1;Brain inhibitory neurons: 36.6;Cardiomyocytes: 41.4;Choroid plexus epithelial cells: 20.6;Ependymal cells: 23.3;Epicardial cells: 15.9;Microglia: 40.8;Oligodendrocyte progenitor cells: 31.1;Oligodendrocytes: 26.1;Other brain neurons: 39.8;Retinal ganglion cells: 15.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018797 Approved Approved Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 21: Testis - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 24: Non-specific - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" Cytosol "HPA018797: " "unprognostic (2.35e-1)" "unprognostic (4.97e-2)" "unprognostic (4.94e-2)" "unprognostic (3.68e-3)" "unprognostic (2.66e-1)" "unprognostic (4.75e-2)" "unprognostic (4.58e-1)" "potential prognostic favorable (4.40e-4)" "unprognostic (1.63e-1)" "potential prognostic favorable (8.44e-4)" "potential prognostic favorable (6.02e-8)" "unprognostic (2.41e-2)" "unprognostic (2.27e-1)" "unprognostic (1.58e-1)" "unprognostic (2.61e-1)" "unprognostic (6.72e-2)" "unprognostic (6.45e-2)" "unprognostic (5.28e-2)" "unprognostic (2.33e-1)" "unprognostic (1.71e-2)" "unprognostic (6.25e-2)" "unprognostic (1.13e-1)" "potential prognostic unfavorable (6.30e-5)" "unprognostic (9.02e-2)" "unprognostic (3.66e-1)" "unprognostic (8.85e-2)" "unprognostic (7.96e-2)" "unprognostic (2.57e-2)" "unprognostic (2.72e-1)" "unprognostic (3.45e-2)" "unprognostic (1.22e-1)" CHL1 "CALL, FLJ44930, L1CAM2, MGC132578" ENSG00000134121 "Cell adhesion molecule L1 like" O00533 3 196763-409417 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 62.8;ovary: 31.9" "Cell type enhanced" "Detected in many" "Astrocytes: 381.5;Bergmann glia: 1191.4;Brain excitatory neurons: 356.9;Brain inhibitory neurons: 350.9;Conjunctival goblet cells: 282.5;Oligodendrocyte progenitor cells: 992.9;Other brain neurons: 553.0;Pituicytes/FSCs: 356.5;Renal collecting duct intercalated cells: 257.3;Respiratory secretory cells: 327.2;Schwann cells: 767.9" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 40.5;Kidney Renal Papillary Cell Carcinoma (TCGA): 36.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 33 "memory B-cell: 2.8;naive B-cell: 3.8" "Lineage enriched" "Detected in single" 38 "B-cells: 3.8" "Group enriched" "Detected in many" 7 "Rhabdoid: 38.6;skin cancer: 30.5" "Colon - Enteric glia cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003345, CAB026120" Enhanced "Secreted in brain" "Developmental protein" NA NA 530000000 "Cluster 34: B-cells - Unknown function" "Cluster 73: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 109: Neurons - Neuronal signaling" "CAB026120: , HPA003345: " "unprognostic (9.76e-2)" "unprognostic (5.72e-2)" "unprognostic (3.50e-1)" "unprognostic (7.81e-2)" "unprognostic (7.47e-2)" "unprognostic (2.23e-3)" "unprognostic (9.77e-3)" "unprognostic (1.02e-1)" "unprognostic (1.28e-1)" "unprognostic (6.39e-3)" "unprognostic (2.53e-1)" "potential prognostic favorable (3.30e-5)" "unprognostic (6.44e-2)" "unprognostic (1.51e-1)" "unprognostic (3.19e-1)" "unprognostic (3.45e-1)" "unprognostic (2.19e-1)" "unprognostic (8.01e-2)" "unprognostic (2.54e-3)" "unprognostic (1.65e-1)" "unprognostic (3.76e-1)" "unprognostic (1.12e-1)" "unprognostic (1.40e-1)" "unprognostic (3.12e-1)" "unprognostic (6.47e-2)" "unprognostic (5.08e-3)" "unprognostic (8.84e-2)" CHM "DXS540, REP-1, TCD" ENSG00000188419 "CHM Rab escort protein" P24386 X 85861180-86047561 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "GTPase activation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003231, CAB016171" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 36: Non-specific - mRNA processing" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 49 Nucleoplasm Cytosol "CAB016171: , HPA003231: " "unprognostic (1.25e-1)" "unprognostic (1.18e-2)" "unprognostic (1.67e-1)" "unprognostic (4.49e-3)" "unprognostic (2.47e-1)" "unprognostic (1.01e-1)" "unprognostic (4.47e-1)" "unprognostic (2.45e-1)" "unprognostic (2.55e-1)" "unprognostic (5.86e-3)" "potential prognostic favorable (2.91e-7)" "unprognostic (2.24e-3)" "unprognostic (1.74e-1)" "unprognostic (1.57e-2)" "unprognostic (1.22e-1)" "unprognostic (6.97e-2)" "potential prognostic unfavorable (9.83e-4)" "unprognostic (2.79e-2)" "unprognostic (2.52e-1)" "unprognostic (1.25e-1)" "unprognostic (2.20e-2)" "unprognostic (4.07e-2)" "unprognostic (2.85e-2)" "unprognostic (1.02e-1)" "unprognostic (3.36e-2)" "unprognostic (2.31e-1)" "unprognostic (2.09e-2)" "unprognostic (1.87e-1)" "unprognostic (2.09e-1)" "unprognostic (5.88e-2)" "unprognostic (4.62e-2)" CHML REP-2 ENSG00000203668 "CHM like Rab escort protein" P26374 1 241628851-241640369 "Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 10.0;Extravillous trophoblasts: 8.4;Late spermatids: 15.2;Megakaryocyte progenitors: 9.0;Megakaryocyte-Erythroid progenitors: 8.2;Megakaryocytes: 12.4" "Cell type enhanced" "Detected in some" "vascular associated smooth muscle cell: 2.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Pituitary gland - Somatotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029627, HPA029628, HPA062967" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 61: Non-specific - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 45: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 48 "Nucleoplasm, Cytosol" "HPA029627: , HPA029628: , HPA062967: " "unprognostic (1.92e-1)" "unprognostic (3.69e-2)" "unprognostic (1.28e-1)" "unprognostic (3.72e-2)" "unprognostic (4.34e-2)" "unprognostic (3.50e-1)" "unprognostic (2.49e-1)" "unprognostic (7.71e-2)" "unprognostic (6.64e-2)" "unprognostic (3.38e-3)" "unprognostic (1.05e-3)" "unprognostic (4.18e-2)" "unprognostic (2.89e-3)" "potential prognostic unfavorable (4.65e-5)" "unprognostic (4.80e-2)" "unprognostic (2.17e-3)" "unprognostic (4.33e-2)" "unprognostic (2.61e-1)" "potential prognostic favorable (8.45e-4)" "unprognostic (4.64e-2)" "unprognostic (4.20e-1)" "unprognostic (1.38e-3)" "unprognostic (2.41e-3)" "unprognostic (2.89e-2)" "unprognostic (1.43e-1)" "unprognostic (4.95e-2)" "unprognostic (3.95e-2)" "unprognostic (1.95e-2)" "unprognostic (2.69e-1)" "unprognostic (8.11e-3)" "unprognostic (2.29e-1)" CHMP1A "CHMP1, KIAA0047, PCOLN3, PRSM1, Vps46A" ENSG00000131165 "Charged multivesicular body protein 1A" Q9HD42 16 89640816-89657738 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Protein transport, Transcription, Transcription regulation, Transport" Repressor Neurodegeneration "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 271.3;Esophageal suprabasal cells: 145.9;Late spermatids: 208.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006776 Supported Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 51: Neurons - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 54 "Nucleoplasm, Centrosome, Cytosol" "HPA006776: " "unprognostic (4.08e-1)" "unprognostic (3.47e-2)" "unprognostic (1.44e-1)" "unprognostic (2.77e-1)" "unprognostic (9.40e-2)" "unprognostic (1.66e-1)" "unprognostic (2.77e-2)" "unprognostic (3.43e-2)" "unprognostic (9.81e-3)" "unprognostic (4.29e-2)" "unprognostic (2.68e-3)" "unprognostic (4.85e-3)" "unprognostic (1.03e-2)" "potential prognostic unfavorable (6.51e-4)" "unprognostic (3.19e-2)" "unprognostic (2.60e-2)" "unprognostic (8.15e-2)" "unprognostic (3.41e-2)" "unprognostic (3.01e-1)" "unprognostic (1.01e-1)" "unprognostic (1.65e-1)" "unprognostic (1.09e-1)" "unprognostic (3.46e-2)" "unprognostic (2.00e-1)" "unprognostic (6.07e-2)" "unprognostic (1.81e-1)" "unprognostic (1.43e-1)" "unprognostic (2.24e-1)" "unprognostic (1.44e-1)" "unprognostic (2.05e-1)" "unprognostic (2.49e-3)" CHMP1B "C18orf2, CHMP1.5, Vps46B" ENSG00000255112 "Charged multivesicular body protein 1B" Q7LBR1 18 11851413-11854444 "Predicted intracellular proteins" "Cell cycle, Cell division, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "skeletal muscle: 344.7" "Cell type enhanced" "Detected in some" "cDC: 2.8;Conjunctival goblet cells: 2.9;Endometrial secretory cells: 2.3;Enterocytes: 2.7;Epididymal efferent duct absorptive cells: 2.5;Melanocytes: 2.3;Ocular epithelial cells: 2.7;Parietal cells: 3.5;Suprabasal keratinocytes: 3.9" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA061997, HPA062896" Supported Approved Nucleoplasm,Midbody Yes No "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 23: Choroid plexus - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 82: Dendritic cells - Antigen presentation" 25 "Nucleoplasm, Midbody" "HPA061997: , HPA062896: " "unprognostic (1.50e-2)" "unprognostic (3.32e-1)" "unprognostic (9.47e-2)" "unprognostic (2.97e-1)" "unprognostic (1.79e-2)" "unprognostic (1.61e-1)" "unprognostic (3.82e-1)" "unprognostic (4.26e-3)" "unprognostic (3.33e-3)" "unprognostic (2.74e-1)" "validated prognostic favorable (1.24e-8)" "validated prognostic favorable (7.60e-4)" "unprognostic (3.22e-2)" "unprognostic (9.79e-2)" "unprognostic (1.06e-1)" "unprognostic (3.29e-2)" "unprognostic (6.01e-3)" "unprognostic (2.27e-1)" "unprognostic (1.82e-1)" "unprognostic (1.95e-1)" "unprognostic (1.58e-2)" "unprognostic (7.96e-3)" "unprognostic (5.40e-2)" "unprognostic (1.53e-1)" "unprognostic (9.93e-2)" "unprognostic (4.12e-2)" "unprognostic (2.48e-1)" "unprognostic (1.76e-2)" "unprognostic (4.28e-1)" "unprognostic (1.90e-3)" "unprognostic (2.77e-1)" CHMP2A "BC-2, CHMP2, VPS2, VPS2A" ENSG00000130724 "Charged multivesicular body protein 2A" O43633 19 58551452-58555105 "Essential proteins, Predicted intracellular proteins" "Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 550.3;Esophageal apical cells: 1198.5;Esophageal suprabasal cells: 602.4;Syncytiotrophoblasts: 612.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041153, HPA042031" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 68000 "Cluster 21: Neutrophils - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 38 Cytosol "Nucleoplasm, Plasma membrane" "HPA041153: , HPA042031: " "unprognostic (2.44e-1)" "unprognostic (8.76e-2)" "unprognostic (8.44e-2)" "unprognostic (1.25e-1)" "unprognostic (4.42e-2)" "unprognostic (2.93e-2)" "unprognostic (2.05e-2)" "unprognostic (1.19e-2)" "unprognostic (9.99e-2)" "unprognostic (2.21e-1)" "unprognostic (5.50e-2)" "unprognostic (1.79e-1)" "unprognostic (3.70e-3)" "unprognostic (2.80e-1)" "unprognostic (4.33e-2)" "unprognostic (2.10e-2)" "unprognostic (4.74e-2)" "unprognostic (8.39e-2)" "unprognostic (5.57e-2)" "unprognostic (8.59e-3)" "unprognostic (1.73e-2)" "unprognostic (9.32e-2)" "unprognostic (9.22e-2)" "unprognostic (3.00e-1)" "unprognostic (2.94e-3)" "unprognostic (5.68e-2)" "unprognostic (1.20e-1)" "unprognostic (1.38e-1)" "unprognostic (3.48e-2)" "unprognostic (6.32e-2)" "unprognostic (5.32e-3)" CHMP2B "CHMP2.5, DKFZP564O123, VPS2B" ENSG00000083937 "Charged multivesicular body protein 2B" Q9UQN3 3 87227271-87255556 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 648.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035069, HPA052754" Uncertain Approved Cytosol NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 13 Cytosol "HPA035069: , HPA052754: " "unprognostic (1.68e-2)" "unprognostic (6.26e-3)" "unprognostic (1.97e-2)" "unprognostic (9.40e-3)" "unprognostic (7.70e-3)" "unprognostic (1.10e-2)" "unprognostic (4.16e-2)" "unprognostic (2.37e-3)" "unprognostic (2.42e-1)" "unprognostic (8.54e-2)" "potential prognostic favorable (2.14e-7)" "unprognostic (1.95e-3)" "unprognostic (7.27e-2)" "unprognostic (1.95e-2)" "potential prognostic unfavorable (5.10e-4)" "unprognostic (8.45e-2)" "unprognostic (1.30e-1)" "unprognostic (5.48e-3)" "unprognostic (3.24e-1)" "unprognostic (1.20e-1)" "unprognostic (7.12e-2)" "potential prognostic unfavorable (1.32e-4)" "unprognostic (4.36e-3)" "unprognostic (3.77e-2)" "unprognostic (1.84e-2)" "unprognostic (1.33e-2)" "unprognostic (1.57e-1)" "unprognostic (9.32e-2)" "unprognostic (3.04e-1)" "unprognostic (1.37e-2)" "unprognostic (1.08e-1)" CHMP3 "CGI-149, NEDF, VPS24" ENSG00000115561 "Charged multivesicular body protein 3" Q9Y3E7 2 86503430-86563479 "Essential proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 443.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015673, HPA073383" Supported NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 14: Neurons - Synaptic function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 15: Non-specific - Protein processing" 19 "HPA015673: , HPA073383: " "unprognostic (9.92e-2)" "unprognostic (1.84e-2)" "unprognostic (2.37e-1)" "unprognostic (5.75e-2)" "unprognostic (3.03e-1)" "unprognostic (2.15e-1)" "unprognostic (7.90e-2)" "unprognostic (2.68e-1)" "unprognostic (7.59e-2)" "potential prognostic favorable (2.71e-9)" "unprognostic (4.14e-2)" "unprognostic (1.41e-1)" "potential prognostic unfavorable (2.82e-6)" "unprognostic (2.79e-2)" "unprognostic (3.07e-1)" "unprognostic (2.43e-1)" "unprognostic (2.79e-1)" "unprognostic (3.91e-3)" "potential prognostic unfavorable (2.50e-5)" "potential prognostic unfavorable (3.77e-4)" "unprognostic (3.14e-1)" "unprognostic (1.02e-1)" "unprognostic (2.66e-1)" "unprognostic (2.30e-2)" "unprognostic (7.64e-2)" "unprognostic (8.06e-2)" "unprognostic (4.69e-2)" "unprognostic (2.79e-1)" "unprognostic (4.16e-2)" CHMP4A "C14orf123, HSPC134, VPS32A" ENSG00000254505 "Charged multivesicular body protein 4A" Q9BY43 14 24209615-24213830 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Astrocytes: 11.9;Bergmann glia: 11.3;Brain excitatory neurons: 11.5;Brain inhibitory neurons: 10.5;Choroid plexus epithelial cells: 5.6;Ependymal cells: 9.7;Microglia: 19.8;Oligodendrocyte progenitor cells: 9.8;Oligodendrocytes: 16.5;Other brain neurons: 11.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068473 Approved NA NA 360000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 47: Endothelial cells - Vasculature" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 22: Non-specific - Basic cellular functions" 16 "HPA068473: " "unprognostic (2.19e-2)" "unprognostic (3.14e-3)" "unprognostic (2.23e-1)" "unprognostic (3.18e-2)" "unprognostic (5.45e-3)" "unprognostic (2.86e-1)" "unprognostic (8.99e-2)" "unprognostic (1.51e-3)" "unprognostic (2.77e-3)" "potential prognostic unfavorable (7.64e-4)" "potential prognostic favorable (3.04e-4)" "unprognostic (4.84e-3)" "unprognostic (4.16e-2)" "potential prognostic unfavorable (1.51e-6)" "unprognostic (5.68e-2)" "unprognostic (1.10e-2)" "unprognostic (1.86e-3)" "unprognostic (5.02e-2)" "unprognostic (4.47e-2)" "unprognostic (3.12e-1)" "unprognostic (1.82e-1)" "potential prognostic unfavorable (7.60e-4)" "unprognostic (3.19e-2)" "unprognostic (1.46e-1)" "unprognostic (7.36e-2)" "unprognostic (2.51e-1)" "unprognostic (2.40e-1)" "unprognostic (7.52e-2)" "unprognostic (7.36e-2)" "unprognostic (6.71e-2)" "unprognostic (8.84e-2)" CHMP4B "C20orf178, dJ553F4.4, Shax1, SNF7-2, VPS32B" ENSG00000101421 "Charged multivesicular body protein 4B" Q9H444 20 33811348-33854366 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction, Protein transport, Transport" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Colonocytes: 483.2;Enterocytes: 564.6;Esophageal apical cells: 776.2;Esophageal suprabasal cells: 592.3;Syncytiotrophoblasts: 602.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Inner root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041401, HPA051751" Enhanced NA NA 60000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 74 "HPA041401: , HPA051751: " "unprognostic (2.91e-3)" "unprognostic (4.06e-1)" "unprognostic (2.75e-1)" "unprognostic (3.23e-2)" "unprognostic (2.69e-2)" "unprognostic (1.46e-1)" "unprognostic (1.14e-1)" "unprognostic (2.02e-1)" "unprognostic (8.41e-2)" "unprognostic (1.10e-2)" "unprognostic (2.60e-3)" "unprognostic (1.73e-1)" "unprognostic (3.16e-1)" "potential prognostic unfavorable (2.34e-4)" "unprognostic (1.63e-3)" "unprognostic (7.03e-2)" "unprognostic (5.22e-3)" "unprognostic (5.04e-2)" "unprognostic (7.06e-2)" "unprognostic (1.83e-1)" "unprognostic (3.32e-1)" "unprognostic (6.34e-3)" "unprognostic (8.13e-2)" "unprognostic (3.50e-1)" "unprognostic (2.24e-1)" "unprognostic (2.83e-2)" "unprognostic (2.96e-1)" "unprognostic (3.67e-1)" "unprognostic (7.41e-2)" "unprognostic (2.75e-1)" "unprognostic (1.52e-2)" CHMP4C "MGC22825, Shax3, VPS32C" ENSG00000164695 "Charged multivesicular body protein 4C" Q96CF2 8 81732448-81759515 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 39.4" "Cell type enhanced" "Detected in many" "Enterocytes: 86.4;Esophageal apical cells: 308.8" "Group enriched" "Detected in some" 11 "choroid plexus epithelial cell: 4.3;endothelial cell: 6.8;vascular associated smooth muscle cell: 7.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "NK-cell: 1.9" "Lineage enriched" "Detected in single" 5 "NK-cells: 1.9" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Pituitary gland - Somatotropes, Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA023763, HPA023799" Enhanced Approved "Microtubules,Cytokinetic bridge" Yes NA "Cluster 14: Non-specific - Unknown function" "Cluster 60: Stomach - Digestion" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 40: Non-specific - Unknown function" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 18 "Microtubules, Cytokinetic bridge" "HPA023763: , HPA023799: " "unprognostic (2.26e-1)" "unprognostic (3.93e-2)" "unprognostic (4.02e-2)" "potential prognostic unfavorable (4.58e-6)" "unprognostic (4.50e-2)" "unprognostic (1.40e-2)" "unprognostic (9.45e-2)" "potential prognostic unfavorable (3.90e-4)" "potential prognostic favorable (2.20e-6)" "unprognostic (2.20e-3)" "unprognostic (7.87e-3)" "unprognostic (3.48e-2)" "unprognostic (1.11e-3)" "unprognostic (2.66e-3)" "unprognostic (1.20e-1)" "potential prognostic unfavorable (9.22e-4)" "unprognostic (4.16e-2)" "unprognostic (2.07e-2)" "unprognostic (1.67e-2)" "potential prognostic unfavorable (1.85e-4)" "unprognostic (1.05e-2)" "unprognostic (7.51e-3)" "unprognostic (4.59e-2)" "unprognostic (5.61e-2)" "unprognostic (1.35e-1)" "unprognostic (2.73e-3)" "unprognostic (2.18e-1)" "unprognostic (3.61e-1)" "unprognostic (4.70e-1)" CHMP5 "C9orf83, CGI-34, HSPC177, SNF7DC2, Vps60" ENSG00000086065 "Charged multivesicular body protein 5" Q9NZZ3 9 33264879-33282070 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 371.8;Esophageal apical cells: 1078.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033874, HPA042883, HPA056437" Enhanced Supported Microtubules,Midbody,Cytosol Yes No "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 72: Kidney - Transmembrane transport" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 29 "Microtubules, Cytosol" Midbody "CAB033874: , HPA042883: , HPA056437: " "unprognostic (4.39e-2)" "unprognostic (6.50e-2)" "unprognostic (6.22e-3)" "unprognostic (2.66e-1)" "unprognostic (2.25e-1)" "unprognostic (3.13e-2)" "unprognostic (2.76e-1)" "unprognostic (2.73e-1)" "unprognostic (9.04e-2)" "unprognostic (1.97e-1)" "potential prognostic favorable (2.58e-9)" "unprognostic (3.04e-2)" "unprognostic (8.51e-3)" "unprognostic (1.22e-2)" "unprognostic (3.40e-2)" "unprognostic (1.82e-2)" "unprognostic (3.29e-2)" "unprognostic (6.35e-2)" "unprognostic (7.55e-2)" "unprognostic (9.26e-2)" "unprognostic (1.18e-3)" "unprognostic (4.99e-2)" "unprognostic (4.04e-2)" "unprognostic (4.71e-2)" "unprognostic (3.08e-1)" "unprognostic (1.42e-1)" "unprognostic (1.65e-1)" "unprognostic (6.65e-2)" "unprognostic (5.53e-1)" "unprognostic (3.68e-1)" "unprognostic (4.84e-1)" CHMP6 "FLJ11749, VPS20" ENSG00000176108 "Charged multivesicular body protein 6" Q96FZ7 17 80991598-81009517 "Essential proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Platelets: 236.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023001, HPA024460" Approved NA NA 10000 "Cluster 25: Non-specific - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 27: Breast cancer - Unknown function" "Cluster 47: Platelets - Hemostasis" 19 "HPA023001: , HPA024460: " "unprognostic (1.24e-1)" "unprognostic (2.55e-2)" "unprognostic (2.66e-1)" "unprognostic (2.16e-1)" "unprognostic (2.28e-3)" "unprognostic (3.09e-1)" "unprognostic (4.54e-2)" "unprognostic (1.26e-1)" "unprognostic (1.58e-1)" "unprognostic (2.13e-2)" "validated prognostic favorable (5.97e-5)" "validated prognostic favorable (8.45e-4)" "unprognostic (2.09e-3)" "unprognostic (1.93e-2)" "potential prognostic unfavorable (3.17e-4)" "unprognostic (8.98e-2)" "unprognostic (1.18e-2)" "unprognostic (1.03e-1)" "unprognostic (6.01e-3)" "unprognostic (6.78e-2)" "unprognostic (8.30e-2)" "unprognostic (6.09e-2)" "unprognostic (3.86e-2)" "unprognostic (5.74e-2)" "unprognostic (6.07e-2)" "unprognostic (9.65e-2)" "unprognostic (1.15e-1)" "unprognostic (1.41e-1)" "unprognostic (1.93e-1)" "unprognostic (1.07e-1)" "unprognostic (2.53e-1)" CHMP7 MGC29816 ENSG00000147457 "Charged multivesicular body protein 7" Q8WUX9 8 23243637-23262000 "Essential proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 30.5" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 10 "B-cells: 35.7;T-cells: 76.5" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036119 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 6: Non-specific - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 17 Nucleoplasm Cytosol "HPA036119: " "unprognostic (1.10e-2)" "unprognostic (1.29e-1)" "unprognostic (4.22e-3)" "unprognostic (2.09e-1)" "unprognostic (3.30e-2)" "unprognostic (1.65e-1)" "unprognostic (1.60e-2)" "potential prognostic favorable (8.88e-4)" "unprognostic (5.49e-3)" "unprognostic (4.05e-1)" "unprognostic (1.87e-2)" "unprognostic (7.94e-2)" "unprognostic (3.73e-3)" "unprognostic (1.00e-1)" "unprognostic (1.36e-1)" "unprognostic (1.77e-2)" "unprognostic (1.73e-1)" "unprognostic (1.39e-1)" "unprognostic (1.26e-1)" "unprognostic (7.18e-2)" "unprognostic (7.03e-3)" "unprognostic (2.08e-1)" "unprognostic (5.25e-2)" "unprognostic (8.53e-2)" "unprognostic (5.13e-2)" "unprognostic (1.62e-2)" "unprognostic (1.49e-1)" "potential prognostic favorable (9.55e-4)" "unprognostic (2.93e-3)" "unprognostic (4.40e-2)" "unprognostic (1.62e-1)" CHN1 "ARHGAP2, CHN, DURS2, n-chimerin, RhoGAP2" ENSG00000128656 "Chimerin 1" P15882 2 174798809-175005381 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Neurogenesis "GTPase activation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 19 "brain: 842.8" "Cell type enhanced" "Detected in many" "Astrocytes: 209.3;Brain excitatory neurons: 403.6;Brain inhibitory neurons: 260.3;Cone photoreceptor cells: 236.0;Corticotrophs: 213.1;Gonadotrophs: 204.0;Lactotrophs: 384.5;Myosatellite cells: 314.7;Pituicytes/FSCs: 439.2;Pituitary stem cells: 303.4;Somatotrophs: 243.1;Thyrotrophs: 433.5" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 84.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory CD4 T-cell: 6.8;memory CD8 T-cell: 2.2;T-reg: 8.5" "Lineage enriched" "Detected in single" 19 "T-cells: 8.5" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Adrenal gland - Adrenal cortex cells, Colon - Enteric glia cells, Minor Salivary Gland - Endothelial cells, Prostate - Fibroblasts, Skeletal muscle - Endothelial cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036111 Approved Cytosol NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 78: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 35: Neurons - Synaptic function & neurogenesis" 6 Cytosol "HPA036111: " "unprognostic (1.39e-1)" "unprognostic (4.06e-3)" "unprognostic (3.44e-1)" "unprognostic (2.41e-2)" "unprognostic (1.14e-1)" "unprognostic (5.32e-1)" "unprognostic (7.19e-2)" "unprognostic (6.60e-3)" "unprognostic (3.04e-2)" "unprognostic (3.53e-2)" "potential prognostic unfavorable (7.59e-4)" "unprognostic (2.67e-2)" "unprognostic (6.60e-2)" "unprognostic (2.94e-1)" "unprognostic (2.85e-2)" "unprognostic (1.94e-1)" "unprognostic (5.29e-2)" "unprognostic (1.04e-1)" "unprognostic (6.41e-2)" "unprognostic (3.38e-2)" "unprognostic (2.74e-2)" "unprognostic (4.77e-2)" "unprognostic (7.12e-2)" "unprognostic (5.44e-2)" "unprognostic (9.27e-2)" "unprognostic (8.39e-3)" "unprognostic (5.85e-2)" "unprognostic (1.61e-3)" "unprognostic (8.90e-2)" "unprognostic (8.12e-2)" "unprognostic (4.24e-1)" CHN2 "ARHGAP3, RhoGAP3" ENSG00000106069 "Chimerin 2" P52757 7 29146547-29514328 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 170.8;intestine: 72.2" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 737.9;Cardiomyocytes: 701.2;cDC: 513.6;Choroid plexus epithelial cells: 680.0;Hepatocytes: 484.3;Mast cells: 1230.1;Microglia: 461.3;Oligodendrocytes: 498.4;Pancreatic acinar cells: 631.7;Retinal bipolar cells: 468.1;Tuft cells: 1302.7" "Cell type enhanced" "Detected in all" "upper rhombic lip: 2324.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Liver - Hepatocytes, Prostate - Smooth muscle cells" "Region enriched" "Detected in all" 4 "cerebellum: 413.0" "Low region specificity" "Detected in all" "HPA018989, HPA019026" Approved Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 27: Cerebellum - Synaptic function" "Cluster 25: Non-specific - Transcription" "Cluster 1: Neuronal - Visual perception" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 9 Nucleoplasm "Nuclear bodies" "HPA018989: , HPA019026: " "unprognostic (7.11e-3)" "unprognostic (6.03e-2)" "unprognostic (1.62e-1)" "unprognostic (8.61e-2)" "unprognostic (3.80e-1)" "unprognostic (5.39e-2)" "unprognostic (2.52e-1)" "unprognostic (1.39e-2)" "unprognostic (4.12e-2)" "unprognostic (1.12e-1)" "unprognostic (3.27e-2)" "unprognostic (2.90e-3)" "unprognostic (9.61e-2)" "unprognostic (1.44e-1)" "unprognostic (2.70e-1)" "unprognostic (1.17e-1)" "unprognostic (1.82e-1)" "unprognostic (4.59e-2)" "unprognostic (2.78e-3)" "unprognostic (2.08e-1)" "potential prognostic unfavorable (9.44e-6)" "unprognostic (1.78e-1)" "potential prognostic favorable (5.16e-4)" "unprognostic (1.15e-1)" "unprognostic (3.60e-3)" "unprognostic (2.63e-2)" "unprognostic (2.41e-1)" "unprognostic (2.35e-2)" "unprognostic (3.01e-2)" "unprognostic (3.57e-2)" "unprognostic (1.43e-1)" CHODL "C21orf68, FLJ12627, MT75, PRED12" ENSG00000154645 Chondrolectin Q9H9P2 21 17901263-18267373 "Predicted intracellular proteins, Predicted membrane proteins" Neurogenesis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 13.3;testis: 29.0" "Cell type enhanced" "Detected in many" "Breast lactating cells: 72.8;Gonadotrophs: 132.7;Leydig cells: 103.7;Oocytes: 69.1;Pituitary stem cells: 78.7;Plasma cells: 82.2;Sertoli cells: 278.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 11.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "MAIT T-cell: 1.5" "Lineage enriched" "Detected in single" 7 "T-cells: 1.5" "Cancer enhanced" "Detected in some" "Neuroblastoma: 7.3;Rhabdoid: 4.8" "Colon - Enteric glia cells, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Testis - Sertoli cells, Thyroid gland - Fibroblasts" "Group enriched" "Detected in many" 4 "basal ganglia: 3.9;hypothalamus: 12.3;pons and medulla: 10.9" "Group enriched" "Detected in all" 4 "olfactory bulb: 99.3;spinal cord: 66.1" "HPA017282, HPA057559" Enhanced Approved Centrosome,Cytosol NA NA "Cluster 1: T-cells - Unknown function" "Cluster 47: Testis - Mixed function" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 1: Neuronal - Visual perception" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 11 Cytosol Centrosome "HPA017282: , HPA057559: " "unprognostic (4.66e-2)" "unprognostic (1.96e-1)" "potential prognostic unfavorable (4.81e-4)" "unprognostic (6.53e-3)" "unprognostic (2.39e-3)" "unprognostic (7.88e-2)" "unprognostic (5.00e-2)" "unprognostic (8.31e-2)" "potential prognostic favorable (3.84e-4)" "unprognostic (1.22e-2)" "unprognostic (7.89e-2)" "unprognostic (1.83e-1)" "unprognostic (2.10e-2)" "unprognostic (2.11e-3)" "unprognostic (8.59e-3)" "unprognostic (8.69e-2)" "unprognostic (1.59e-1)" "unprognostic (6.54e-2)" "unprognostic (2.95e-1)" "unprognostic (1.13e-1)" "unprognostic (1.79e-1)" "potential prognostic unfavorable (5.12e-4)" CHORDC1 "CHP-1, CHP1" ENSG00000110172 "Cysteine and histidine rich domain containing 1" Q9UHD1 11 90200429-90223077 "Essential proteins, Predicted intracellular proteins" "Stress response" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 82.1;Ependymal cells: 117.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041040 Approved Approved Cytosol NA NA 77000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 102: Non-specific - Mixed function" 21 Cytosol "HPA041040: " "unprognostic (1.34e-2)" "unprognostic (1.49e-3)" "unprognostic (2.30e-2)" "unprognostic (7.59e-2)" "unprognostic (1.24e-1)" "unprognostic (8.26e-2)" "unprognostic (1.62e-1)" "unprognostic (1.27e-1)" "unprognostic (1.97e-2)" "unprognostic (1.99e-1)" "unprognostic (2.04e-1)" "unprognostic (1.60e-1)" "potential prognostic unfavorable (2.37e-5)" "potential prognostic unfavorable (3.81e-8)" "unprognostic (4.40e-2)" "validated prognostic unfavorable (1.15e-5)" "validated prognostic unfavorable (5.26e-5)" "unprognostic (1.77e-2)" "unprognostic (4.55e-2)" "unprognostic (1.43e-1)" "unprognostic (5.47e-2)" "unprognostic (1.77e-1)" "potential prognostic unfavorable (3.00e-9)" "unprognostic (3.18e-2)" "unprognostic (2.92e-3)" "unprognostic (2.11e-1)" "unprognostic (1.57e-1)" "unprognostic (2.26e-1)" "unprognostic (2.39e-2)" "unprognostic (3.38e-1)" "unprognostic (5.53e-3)" CHP1 "CHP, p22, p24, Sid470p, SLC9A1BP" ENSG00000187446 "Calcineurin like EF-hand protein 1" Q99653 15 41230839-41281887 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Protein kinase inhibitor" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 442.6;Enterocytes: 493.5;Esophageal apical cells: 923.3;Hepatocytes: 417.9;Parietal cells: 823.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006616 Approved Approved Vesicles NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 76: Non-specific - Metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 26 Vesicles "HPA006616: " "unprognostic (5.21e-2)" "unprognostic (2.89e-2)" "unprognostic (9.17e-2)" "unprognostic (2.66e-1)" "unprognostic (1.06e-1)" "unprognostic (3.82e-2)" "unprognostic (4.01e-3)" "unprognostic (1.16e-1)" "unprognostic (2.07e-2)" "potential prognostic favorable (1.48e-7)" "unprognostic (1.36e-2)" "unprognostic (6.57e-2)" "potential prognostic favorable (2.98e-4)" "unprognostic (7.13e-2)" "unprognostic (3.90e-1)" "unprognostic (2.98e-1)" "unprognostic (1.61e-1)" "unprognostic (2.50e-2)" "unprognostic (1.09e-1)" "potential prognostic unfavorable (7.08e-4)" "unprognostic (1.40e-1)" "unprognostic (3.58e-1)" "unprognostic (9.37e-2)" "unprognostic (9.87e-3)" "unprognostic (1.30e-1)" "unprognostic (3.17e-1)" "unprognostic (5.17e-1)" "unprognostic (1.27e-2)" "unprognostic (7.77e-2)" CHP2 ENSG00000166869 "Calcineurin like EF-hand protein 2" O43745 16 23755026-23758935 "Cancer-related genes, Predicted intracellular proteins" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 16 "intestine: 286.9;skin 1: 141.2" "Cell type enhanced" "Detected in some" "Colonocytes: 320.5;Enteric stem cells: 136.1;Enteric transient amplifying cells: 234.6;Enterocytes: 581.6;Goblet cells: 53.5;Paneth cells: 92.8;Respiratory secretory cells: 72.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rectum Adenocarcinoma (TCGA): 20.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 8.6;Bladder cancer: 6.8" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Minor Salivary Gland - Minor salivary gland basal cells, Skin - Keratinocyte (other), Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA055198, CAB072806" Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 9: Non-specific - Receptor signaling" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 1: Enterocytes - Absorption and Digestion" 7 Nucleoplasm "Nucleoli, Cytosol" "CAB072806: , HPA055198: " "unprognostic (2.47e-1)" "unprognostic (9.90e-2)" "unprognostic (1.47e-2)" "unprognostic (7.13e-2)" "unprognostic (5.80e-2)" "unprognostic (8.53e-2)" "unprognostic (2.54e-1)" "unprognostic (2.34e-1)" "unprognostic (3.56e-2)" "unprognostic (3.32e-1)" "unprognostic (5.09e-1)" "unprognostic (1.39e-2)" "unprognostic (1.36e-2)" "unprognostic (4.33e-2)" "unprognostic (3.06e-3)" "potential prognostic unfavorable (6.00e-5)" "unprognostic (4.23e-2)" "unprognostic (1.71e-2)" "unprognostic (6.54e-3)" CHPF "CHSY2, CSS2" ENSG00000123989 "Chondroitin polymerizing factor" Q8IZ52 2 219538954-219543809 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 189.1;Extravillous trophoblasts: 257.7;Migrating cytotrophoblasts: 161.6;Plasma cells: 116.0;Syncytiotrophoblasts: 376.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 6.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - Plasma cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035123 Approved Supported Vesicles,Centrosome,Cytosol NA NA 13000 "Cluster 22: Eosinophils - Transcription" "Cluster 70: Non-specific - Protein processing" "Cluster 44: Non-specific - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." 5 Cytosol "Vesicles, Centrosome" "HPA035123: " "unprognostic (2.93e-1)" "unprognostic (2.70e-3)" "unprognostic (1.34e-1)" "potential prognostic unfavorable (3.07e-5)" "unprognostic (2.15e-1)" "unprognostic (2.44e-1)" "unprognostic (5.94e-3)" "unprognostic (5.67e-2)" "potential prognostic unfavorable (4.48e-4)" "unprognostic (9.56e-2)" "unprognostic (4.18e-1)" "unprognostic (1.46e-1)" "unprognostic (2.92e-1)" "unprognostic (2.03e-1)" "unprognostic (1.81e-1)" "unprognostic (4.84e-3)" "unprognostic (4.78e-2)" "unprognostic (7.61e-2)" "unprognostic (2.32e-1)" "unprognostic (1.28e-2)" "unprognostic (4.79e-2)" "unprognostic (1.35e-1)" "unprognostic (1.42e-1)" "unprognostic (5.94e-2)" "unprognostic (1.34e-1)" "unprognostic (1.24e-1)" "unprognostic (3.31e-1)" "unprognostic (1.38e-1)" "unprognostic (3.53e-1)" "unprognostic (2.98e-2)" "unprognostic (2.00e-2)" CHPF2 "ChSy-3, CSGlcA-T, KIAA1402" ENSG00000033100 "Chondroitin polymerizing factor 2" Q9P2E5 7 151232483-151240979 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 128.9;Epicardial cells: 72.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020992 Approved Approved Nucleoplasm,Cytosol "Intracellular and membrane" Enzyme NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 1 "Nucleoplasm, Cytosol" "HPA020992: " "unprognostic (2.79e-1)" "unprognostic (9.03e-2)" "unprognostic (1.56e-2)" "potential prognostic unfavorable (3.41e-5)" "unprognostic (1.67e-1)" "unprognostic (7.37e-3)" "unprognostic (2.96e-3)" "unprognostic (3.95e-1)" "unprognostic (1.21e-2)" "unprognostic (2.19e-2)" "validated prognostic unfavorable (2.53e-4)" "validated prognostic unfavorable (8.80e-4)" "unprognostic (2.72e-1)" "potential prognostic unfavorable (6.63e-4)" "unprognostic (7.36e-2)" "unprognostic (1.75e-1)" "unprognostic (1.15e-2)" "unprognostic (1.09e-1)" "unprognostic (1.70e-2)" "unprognostic (1.29e-2)" "unprognostic (1.73e-1)" "potential prognostic favorable (7.67e-4)" "unprognostic (2.12e-1)" "unprognostic (2.88e-1)" "unprognostic (1.01e-1)" "unprognostic (1.66e-1)" "unprognostic (3.60e-2)" "unprognostic (1.94e-1)" "unprognostic (2.33e-1)" "unprognostic (9.88e-2)" "unprognostic (6.45e-2)" CHPT1 CPT1 ENSG00000111666 "Choline phosphotransferase 1" Q8WUD6 12 101696947-101744140 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 1239.4;Salivary acinar cells: 703.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 36.8;eosinophil: 14.7" "Lineage enriched" "Detected in all" 8 "granulocytes: 36.8" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067643 Approved Supported Vesicles NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 76: Non-specific - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 6 Vesicles "HPA067643: " "unprognostic (7.33e-2)" "unprognostic (6.08e-3)" "unprognostic (2.48e-1)" "unprognostic (2.07e-2)" "unprognostic (8.59e-2)" "unprognostic (7.27e-2)" "unprognostic (2.52e-1)" "potential prognostic unfavorable (8.63e-4)" "unprognostic (1.08e-1)" "unprognostic (6.46e-3)" "potential prognostic favorable (3.28e-4)" "unprognostic (3.15e-2)" "unprognostic (1.77e-1)" "unprognostic (4.29e-2)" "unprognostic (5.88e-3)" "unprognostic (2.34e-2)" "unprognostic (1.23e-1)" "unprognostic (9.48e-2)" "unprognostic (3.68e-1)" "unprognostic (2.99e-1)" "unprognostic (1.70e-1)" "unprognostic (1.56e-2)" "unprognostic (1.62e-2)" "unprognostic (3.21e-2)" "unprognostic (2.08e-1)" "unprognostic (1.69e-1)" "unprognostic (1.10e-1)" "unprognostic (3.37e-1)" "unprognostic (2.24e-1)" "unprognostic (8.71e-3)" "unprognostic (9.02e-2)" CHRAC1 "CHRAC15, YCL1" ENSG00000104472 "Chromatin accessibility complex subunit 1" Q9NRG0 8 140511311-140517154 "Predicted intracellular proteins" "DNA-binding, DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cell type enhanced" "Detected in all" "oligodendrocyte: 28.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059008 Approved Nucleoplasm NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 40: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 21 Nucleoplasm "HPA059008: " "unprognostic (1.05e-2)" "unprognostic (2.50e-1)" "unprognostic (7.75e-2)" "unprognostic (1.53e-2)" "unprognostic (3.15e-2)" "unprognostic (4.54e-2)" "unprognostic (4.69e-2)" "unprognostic (3.96e-2)" "unprognostic (3.75e-2)" "unprognostic (1.18e-2)" "unprognostic (2.91e-3)" "unprognostic (3.76e-2)" "unprognostic (1.43e-1)" "validated prognostic unfavorable (9.86e-6)" "validated prognostic unfavorable (8.03e-4)" "potential prognostic unfavorable (3.60e-5)" "unprognostic (7.03e-2)" "unprognostic (1.44e-1)" "unprognostic (1.33e-3)" "unprognostic (1.82e-2)" "unprognostic (2.36e-1)" "unprognostic (1.45e-2)" "unprognostic (2.24e-3)" "unprognostic (1.39e-1)" "unprognostic (2.34e-1)" "unprognostic (2.44e-1)" "unprognostic (1.88e-1)" "unprognostic (2.72e-2)" "unprognostic (1.78e-1)" "unprognostic (3.89e-2)" "unprognostic (8.94e-2)" CHRD ENSG00000090539 Chordin Q9H2X0 3 184380054-184390736 "Plasma proteins, Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 71.0;liver: 124.3" "Cell type enhanced" "Detected in some" "Astrocytes: 12.7;Bergmann glia: 12.4;Brain excitatory neurons: 38.6;Brain inhibitory neurons: 11.8;Decidual stromal cells: 25.8;Endometrial stromal cells: 30.9;Fibroblasts: 18.5;Granulosa cells: 12.2;Hepatocytes: 43.4;Oligodendrocyte progenitor cells: 11.9;Pericytes: 25.7;Retinal amacrine cells: 19.0;Vascular smooth muscle cells: 18.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Macrophages, Minor Salivary Gland - Endothelial cells, Prostate - Fibroblasts, Spleen - Fibroblasts_1, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "hippocampal formation: 7.6" HPA035827 Approved "Secreted in other tissues" "Developmental protein" NA NA 270000 "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 34: Non-specific - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 45 "HPA035827: " "unprognostic (1.10e-1)" "unprognostic (1.77e-1)" "unprognostic (4.40e-2)" "unprognostic (1.52e-2)" "unprognostic (3.11e-2)" "unprognostic (2.57e-2)" "unprognostic (2.18e-1)" "unprognostic (5.91e-2)" "unprognostic (1.64e-1)" "unprognostic (3.43e-2)" "unprognostic (6.53e-3)" "unprognostic (2.14e-2)" "unprognostic (3.09e-1)" "unprognostic (2.29e-1)" "unprognostic (1.38e-1)" "unprognostic (1.57e-1)" "unprognostic (1.77e-2)" "unprognostic (1.52e-2)" "unprognostic (1.48e-1)" "unprognostic (1.73e-2)" "unprognostic (3.23e-2)" "unprognostic (2.27e-1)" "unprognostic (1.48e-1)" "unprognostic (3.05e-2)" "unprognostic (6.67e-3)" "unprognostic (3.71e-1)" "unprognostic (1.19e-2)" "unprognostic (1.67e-1)" "unprognostic (6.23e-2)" "unprognostic (3.96e-1)" CHRDL1 "CHL, MGC1, NRLN1" ENSG00000101938 "Chordin like 1" Q9BU40 X 110673856-110795819 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Differentiation, Neurogenesis, Osteogenesis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 176.6;seminal vesicle: 211.4" "Cell type enhanced" "Detected in many" "Adipocytes: 89.7;Astrocytes: 55.9;Bergmann glia: 54.2;Decidual stromal cells: 48.5;Fibro-adipogenic progenitors: 59.9;Fibroblasts: 79.0;Lymphatic endothelial cells: 109.5;Mesothelial cells: 53.9;Müller glia: 115.3;Pituitary stem cells: 77.6" "Cell type enhanced" "Detected in many" "Bergmann glia: 62.1;LAMP5-LHX6 and Chandelier: 123.8" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 24.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "thyroid cancer: 59.3" "Adrenal gland - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblasts_1, Pancreas - Fibroblasts, Prostate - Smooth muscle cells, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_2, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000226, HPA000250" Approved "Secreted in other tissues" "Developmental protein" NA NA 280000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 53: Neurons - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" "HPA000226: , HPA000250: " "unprognostic (1.20e-1)" "unprognostic (8.45e-2)" "unprognostic (7.49e-3)" "unprognostic (1.25e-2)" "unprognostic (7.14e-2)" "unprognostic (4.59e-2)" "unprognostic (1.36e-2)" "unprognostic (1.40e-2)" "unprognostic (1.28e-2)" "unprognostic (2.75e-3)" "unprognostic (7.73e-3)" "unprognostic (3.65e-1)" "unprognostic (2.89e-1)" "potential prognostic favorable (3.09e-4)" "unprognostic (1.76e-2)" "unprognostic (1.35e-3)" "unprognostic (2.08e-1)" "unprognostic (6.09e-2)" "unprognostic (2.72e-1)" "unprognostic (2.91e-2)" "unprognostic (5.88e-2)" "unprognostic (1.68e-1)" "unprognostic (3.30e-2)" "unprognostic (4.36e-2)" "unprognostic (6.23e-2)" "unprognostic (2.40e-3)" "unprognostic (1.30e-1)" "unprognostic (1.03e-1)" "unprognostic (5.89e-2)" CHRDL2 BNF1 ENSG00000054938 "Chordin like 2" Q6WN34 11 74696429-74731426 "Predicted intracellular proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 118.1;gallbladder: 99.4;lymphoid tissue: 109.3;smooth muscle: 114.0" "Cell type enriched" "Detected in some" 21 "Breast lactating cells: 2089.6" "Cell type enhanced" "Detected in some" "deep-layer corticothalamic and 6b: 1.3;splatter: 1.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 5.1;lung cancer: 3.1" "Prostate - Smooth muscle cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Stomach - Fibroblasts, Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA021771, HPA076522" Uncertain Approved Vesicles "Secreted to extracellular matrix" "Developmental protein" NA NA 1200000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 43: Hindbrain - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 4: Breast lactating luminal cells - Lactation" Vesicles "HPA021771: , HPA076522: " "unprognostic (1.47e-2)" "unprognostic (1.22e-2)" "unprognostic (3.59e-1)" "unprognostic (5.20e-3)" "unprognostic (1.51e-1)" "unprognostic (3.28e-2)" "unprognostic (2.39e-2)" "unprognostic (1.98e-1)" "potential prognostic unfavorable (7.64e-4)" "validated prognostic unfavorable (4.14e-4)" "validated prognostic unfavorable (9.06e-4)" "potential prognostic unfavorable (9.61e-4)" "unprognostic (7.17e-2)" "unprognostic (2.50e-2)" "unprognostic (1.33e-2)" "unprognostic (1.39e-2)" "potential prognostic unfavorable (7.18e-4)" "unprognostic (1.02e-1)" "unprognostic (3.16e-1)" "unprognostic (3.64e-2)" "unprognostic (9.15e-2)" "unprognostic (4.78e-2)" "unprognostic (5.06e-2)" "unprognostic (9.38e-3)" "unprognostic (2.27e-1)" "unprognostic (1.07e-1)" "unprognostic (1.83e-1)" "unprognostic (1.26e-2)" CHRFAM7A "CHRNA7-DR1, D-10" ENSG00000166664 "CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion" Q494W8 15 30360566-30393849 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.1;parathyroid gland: 5.3" "Group enriched" "Detected in some" 8 "Distal convoluted tubule cells: 5.4;Loop of henle epithelial cells: 4.1;Papillary tip epithelial cells: 3.5;Podocytes: 5.9;Proximal tubule cells: 2.0;Renal collecting duct intercalated cells: 4.1;Renal collecting duct principal cells: 4.6;Renal connecting tubule cells: 5.3;Retinal horizontal cells: 6.0" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "eosinophil: 2.9" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Adrenocortical cancer: 3.6;Leukemia: 2.6" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 35: Non-specific - Mixed function" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 105: Non-specific - Mixed function" "unprognostic (1.46e-3)" "unprognostic (1.84e-1)" CHRM1 ENSG00000168539 "Cholinergic receptor muscarinic 1" P11229 11 62908679-62921807 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "brain: 48.4;prostate: 27.8;salivary gland: 27.1" "Cell type enriched" "Detected in some" 5 "Prostatic glandular cells: 52.2" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in some" 11 "Kidney Chromophobe (TCGA): 20.6;Prostate Adenocarcinoma (TCGA): 50.4" "Group enriched" "Detected in many" 5 "amygdala: 42.4;basal ganglia: 59.5;cerebral cortex: 69.7;hippocampal formation: 63.2;white matter: 36.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "breast cancer: 3.4;Neuroblastoma: 8.7;prostate cancer: 2.5" "Adrenal gland - Adrenal medulla cells, Breast - Breast glandular cells (progenitors), Colon - Colon enteroendocrine cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Testis - Late spermatids" "Low region specificity" "Detected in many" HPA014101 Enhanced Supported NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" "HPA014101: " "unprognostic (5.10e-3)" "unprognostic (4.49e-2)" "unprognostic (3.23e-2)" "unprognostic (9.83e-2)" "unprognostic (1.02e-2)" "unprognostic (4.48e-2)" "unprognostic (1.07e-1)" "potential prognostic unfavorable (9.82e-5)" "unprognostic (1.81e-2)" CHRM2 ENSG00000181072 "Cholinergic receptor muscarinic 2" P08172 7 136868652-137020255 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 33.8;intestine: 19.4" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 56.0;Brain inhibitory neurons: 218.2;Cardiomyocytes: 545.5;Other brain neurons: 206.1;Retinal amacrine cells: 155.7;Smooth muscle cells: 101.1" "Cell type enhanced" "Detected in all" "midbrain-derived inhibitory: 1544.5" "Cancer enhanced" "Detected in single" "Stomach Adenocarcinoma (TCGA): 1.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Neuroblastoma: 11.0" "Heart muscle - Cardiomyocytes, Liver - Hepatic stellate cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB022338, HPA029795" Approved NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 109: Neurons - Neuronal signaling" "CAB022338: , HPA029795: " "unprognostic (3.61e-1)" "unprognostic (5.88e-2)" "unprognostic (6.31e-3)" "unprognostic (1.78e-2)" CHRM3 ENSG00000133019 "Cholinergic receptor muscarinic 3" P20309 1 239386565-239915452 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 16.5" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 469.0;Brain inhibitory neurons: 475.5;Gastric chief cells: 458.7;Granulosa cells: 429.8;Hematopoietic stem cells: 698.7;Lacrimal acinar cells: 585.2;Mucous neck cells: 597.4;Pancreatic acinar cells: 983.9;Salivary acinar cells: 2061.3;Salivary myoepithelial cells: 1305.7;Smooth muscle cells: 548.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 8.4" "Heart muscle - Smooth muscle cells, Minor Salivary Gland - Minor salivary glandular cells, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA024106, HPA048036" Approved Supported "Nucleoli,Vesicles,Plasma membrane,Primary cilium tip" NA NA "Cluster 82: Salivary gland - Secretion" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 56: Non-specific - Sensory perception" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 4 "Plasma membrane" "Nucleoli, Vesicles, Primary cilium tip" "HPA024106: , HPA048036: " "unprognostic (2.47e-1)" "unprognostic (7.72e-2)" "unprognostic (2.81e-1)" "unprognostic (9.58e-2)" "unprognostic (3.20e-1)" "unprognostic (1.46e-2)" "unprognostic (8.47e-2)" "unprognostic (3.94e-2)" "validated prognostic favorable (2.76e-8)" "validated prognostic favorable (8.41e-4)" "unprognostic (4.06e-1)" "unprognostic (6.82e-2)" "unprognostic (1.99e-2)" "unprognostic (9.97e-2)" "unprognostic (9.67e-2)" "unprognostic (6.00e-2)" "unprognostic (3.09e-1)" "unprognostic (2.29e-1)" "unprognostic (5.62e-2)" "unprognostic (2.44e-1)" "unprognostic (3.08e-2)" "unprognostic (1.16e-3)" CHRM4 ENSG00000180720 "Cholinergic receptor muscarinic 4" P08173 11 46383789-46391776 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.6;intestine: 5.8;lymphoid tissue: 14.4" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 6.2;Early spermatids: 2.5;Goblet cells: 14.8;Late primary spermatocytes: 8.0;Late spermatids: 10.0;Neuroendocrine cells: 3.5;Pancreatic islet cells: 5.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Region enhanced" "Detected in many" "basal ganglia: 44.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Skin - Keratinocyte (granular), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "basal ganglia: 22.1" "CAB022444, HPA072083" Enhanced Uncertain "Nucleoplasm,Golgi apparatus,Plasma membrane,Primary cilium,Primary cilium tip" NA NA "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 33: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 70: Intestinal goblet cells - Mucin production" 2 "Golgi apparatus" "Nucleoplasm, Plasma membrane, Primary cilium, Primary cilium tip" "CAB022444: , HPA072083: " "unprognostic (2.48e-1)" "unprognostic (4.43e-2)" "unprognostic (1.10e-2)" CHRM5 ENSG00000184984 "Cholinergic receptor muscarinic 5" P08912 15 33968497-34067458 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 7.1" "Cell type enhanced" "Detected in many" "Adipocytes: 60.6;Cardiomyocytes: 78.1;Epicardial cells: 204.7;Extravillous trophoblasts: 41.1;Oligodendrocytes: 88.9;Other brain neurons: 44.0;Retinal bipolar cells: 68.5;Retinal ganglion cells: 42.5" "Cell type enhanced" "Detected in all" "eccentric medium spiny neuron: 130.6;oligodendrocyte: 137.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Testis - Early spermatids, Testis - Late spermatids" "Region enhanced" "Detected in many" "hypothalamus: 13.2" "Low region specificity" "Detected in many" HPA013172 Uncertain NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 2 "HPA013172: " "unprognostic (5.59e-3)" "unprognostic (2.69e-2)" "potential prognostic favorable (2.33e-5)" CHRNA1 CHRNA ENSG00000138435 "Cholinergic receptor nicotinic alpha 1 subunit" P02708 2 174747592-174787935 "Disease related genes, Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skeletal muscle: 160.2" "Group enriched" "Detected in some" 6 "Myonuclei: 62.1;Myosatellite cells: 166.5;Thymic myoid cells: 55.7" "Cell type enriched" "Detected in some" 5 "hippocampal dentate gyrus: 60.0" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 11.1" "Group enriched" "Detected in some" 15 "cerebral cortex: 27.1;hippocampal formation: 11.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 16 "Sarcoma: 107.0" "Pituitary gland - Gonadotropes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA071554 Enhanced Supported "Plasma membrane" NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 29: Forebrain - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 1 "Plasma membrane" "HPA071554: " "unprognostic (1.62e-1)" "unprognostic (2.58e-1)" "unprognostic (3.15e-3)" "unprognostic (1.30e-1)" "unprognostic (3.48e-3)" "unprognostic (1.88e-1)" "unprognostic (2.58e-3)" "unprognostic (1.40e-2)" "unprognostic (3.38e-1)" "unprognostic (6.42e-3)" "unprognostic (1.07e-3)" "unprognostic (8.13e-2)" "unprognostic (7.43e-2)" "unprognostic (2.49e-1)" "unprognostic (8.10e-2)" "unprognostic (2.41e-2)" "unprognostic (2.14e-1)" "unprognostic (9.49e-2)" "unprognostic (6.80e-2)" CHRNA10 ENSG00000129749 "Cholinergic receptor nicotinic alpha 10 subunit" Q9GZZ6 11 3665587-3671384 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "skeletal muscle: 44.8" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 5.3;Neutrophils: 9.5;Paneth cells: 3.9;Thymic myoid cells: 4.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Region enriched" "Detected in some" 6 "olfactory bulb: 7.2" "Not detected" "Not detected" NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 15: Non-specific - Transcription" "Cluster 70: DU4475 - Unknown function" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" "unprognostic (6.79e-2)" "unprognostic (1.48e-2)" "unprognostic (6.88e-3)" "unprognostic (1.63e-1)" CHRNA2 ENSG00000120903 "Cholinergic receptor nicotinic alpha 2 subunit" Q15822 8 27459756-27479883 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "prostate: 27.3" "Group enriched" "Detected in some" 6 "Epicardial cells: 22.7;Epididymal efferent duct absorptive cells: 19.6;Platelets: 38.0;Prostatic glandular cells: 34.5;Retinal amacrine cells: 52.8" "Cell type enhanced" "Detected in some" "cerebellar inhibitory: 18.9;CGE interneuron: 27.8;thalamic excitatory: 26.3" "Cancer enriched" "Detected in single" 200 "Prostate Adenocarcinoma (TCGA): 51.0" "Region enhanced" "Detected in all" "thalamus: 157.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 36 "prostate cancer: 26.6" "Pituitary gland - Corticotropes, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in some" "Region enhanced" "Detected in many" "thalamus: 4.9" HPA048348 Supported "Nucleoplasm,Plasma membrane,Cytokinetic bridge" Yes NA "Cluster 38: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" "Plasma membrane" "Nucleoplasm, Cytokinetic bridge" "HPA048348: " "unprognostic (2.40e-1)" "unprognostic (1.76e-1)" "unprognostic (1.39e-2)" CHRNA3 ENSG00000080644 "Cholinergic receptor nicotinic alpha 3 subunit" P32297 15 78593052-78621295 "Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "adrenal gland: 37.1;lymphoid tissue: 61.2;retina: 49.6" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 117.0;Cone photoreceptor cells: 159.4;Oocytes: 32.2;Retinal pigment epithelial cells: 503.0" "Group enriched" "Detected in some" 8 "cerebellar inhibitory: 55.5;midbrain-derived inhibitory: 49.0" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 3.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 20 "Neuroblastoma: 170.3" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA029430 Enhanced Approved "Nuclear speckles,Plasma membrane,Primary cilium tip,Primary cilium transition zone,Basal body,Cytosol" NA NA "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" 1 "Nuclear speckles, Plasma membrane" "Primary cilium tip, Primary cilium transition zone, Basal body, Cytosol" "HPA029430: " "unprognostic (2.28e-1)" "unprognostic (4.23e-2)" "unprognostic (2.44e-1)" "unprognostic (3.19e-2)" "unprognostic (2.23e-1)" "unprognostic (2.20e-1)" "unprognostic (1.65e-2)" "unprognostic (2.25e-1)" "unprognostic (2.63e-3)" "unprognostic (3.56e-1)" CHRNA4 "BFNC, EBN, EBN1" ENSG00000101204 "Cholinergic receptor nicotinic alpha 4 subunit" P43681 20 63343223-63378401 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 82.6" "Cell type enhanced" "Detected in some" "Epididymal efferent duct absorptive cells: 24.5;Epididymal efferent duct ciliated cells: 12.2;Gonadotrophs: 26.3;Hepatocytes: 68.6;Oligodendrocyte progenitor cells: 15.8;Proximal tubule cells: 24.7;Retinal amacrine cells: 16.3;Retinal bipolar cells: 12.4;Retinal horizontal cells: 110.2" "Cell type enhanced" "Detected in many" "CGE interneuron: 31.8;thalamic excitatory: 33.8" "Cancer enhanced" "Detected in some" "Liver Hepatocellular Carcinoma (TCGA): 3.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Bone cancer: 1.0" "Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Pituitary gland - Gonadotropes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "midbrain: 36.5;pons: 34.3;thalamus: 57.0" "CAB034064, HPA046054" Uncertain Approved Vesicles NA NA "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 38: Sub-cortical - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 5 Vesicles "CAB034064: , HPA046054: " "unprognostic (1.73e-1)" "unprognostic (2.82e-1)" "potential prognostic favorable (8.99e-5)" CHRNA5 ENSG00000169684 "Cholinergic receptor nicotinic alpha 5 subunit" P30532 15 78565520-78595269 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 60.0;Differentiating spermatogonia: 64.6;Early primary spermatocytes: 37.2;Oocytes: 175.0;Retinal horizontal cells: 52.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Prostate - Prostate glandular cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA054381 Approved Approved "Plasma membrane,Focal adhesion sites" NA NA "Cluster 21: Testis - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 41: Oocytes - Oogenesis" 26 "Focal adhesion sites" "Plasma membrane" "HPA054381: " "unprognostic (4.42e-2)" "unprognostic (1.93e-1)" "unprognostic (1.91e-1)" "unprognostic (1.13e-1)" "unprognostic (4.33e-2)" "unprognostic (1.89e-1)" "unprognostic (1.78e-1)" "unprognostic (3.36e-1)" "unprognostic (2.08e-3)" "potential prognostic unfavorable (1.36e-4)" "unprognostic (1.82e-1)" "potential prognostic unfavorable (1.49e-6)" "potential prognostic unfavorable (9.12e-5)" "unprognostic (7.28e-3)" "unprognostic (1.24e-1)" "unprognostic (4.34e-2)" "unprognostic (6.47e-2)" "unprognostic (2.67e-2)" "unprognostic (4.42e-2)" "unprognostic (2.05e-1)" "unprognostic (1.58e-2)" "unprognostic (8.42e-2)" "unprognostic (9.05e-2)" "unprognostic (1.18e-2)" "unprognostic (2.35e-1)" "unprognostic (3.17e-1)" "unprognostic (9.68e-3)" CHRNA6 ENSG00000147434 "Cholinergic receptor nicotinic alpha 6 subunit" Q15825 8 42752620-42796392 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "retina: 3.0" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 10.6;Brain excitatory neurons: 3.8;Breast lactating cells: 5.4;Retinal amacrine cells: 30.1;Retinal ganglion cells: 23.2" "Cell type enhanced" "Detected in some" "CGE interneuron: 10.7;upper rhombic lip: 13.3" "Cancer enhanced" "Detected in some" "Lung Squamous Cell Carcinoma (TCGA): 2.7" "Region enhanced" "Detected in many" "cerebellum: 20.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lymphoma: 4.4" "Group enriched" "Detected in many" 7 "midbrain: 20.2;thalamus: 6.3" "Region enriched" "Detected in all" 6 "midbrain: 99.4" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 25: Non-specific - Transcription" "Cluster 50: Lymphoma - Unknown function" "Cluster 109: Neurons - Neuronal signaling" 1 "unprognostic (3.27e-1)" "unprognostic (4.79e-3)" "unprognostic (1.75e-1)" "unprognostic (7.47e-2)" CHRNA7 ENSG00000175344 "Cholinergic receptor nicotinic alpha 7 subunit" P36544 15 31923438-32173018 "FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 7.3;intestine: 9.1" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 53.2;Brain excitatory neurons: 19.5;Brain inhibitory neurons: 37.9;Choroid plexus epithelial cells: 67.4;Enterocytes: 15.3;Epididymal basal cells: 36.5;Foveolar cells: 14.4;Goblet cells: 23.8;Other brain neurons: 46.2;Papillary tip epithelial cells: 16.0" "Cell type enhanced" "Detected in many" "CGE interneuron: 144.7;mammillary body: 168.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 7 "Neuroblastoma: 16.8" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pituitary gland - Thyrotropes, Stomach - Parietal cells" "HPA029422, CAB033624" Enhanced NA NA "Cluster 77: Intestine - Digestion" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 9 "CAB033624: , HPA029422: " "unprognostic (5.56e-2)" "unprognostic (2.72e-1)" "unprognostic (1.72e-1)" "unprognostic (4.13e-2)" "unprognostic (1.92e-1)" "unprognostic (9.08e-2)" "unprognostic (6.56e-2)" "unprognostic (1.83e-1)" "unprognostic (1.41e-3)" "unprognostic (1.97e-1)" "unprognostic (1.31e-2)" "unprognostic (1.85e-1)" "unprognostic (8.26e-3)" CHRNA9 NACHRA9 ENSG00000174343 "Cholinergic receptor nicotinic alpha 9 subunit" Q9UGM1 4 40335333-40355217 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 1.3;Endometrial glandular cells: 1.3;Fallopian tube ciliated cells: 1.1;Kupffer cells: 1.0;Melanocytes: 2.0;pDCs: 1.3;Respiratory ciliated cells: 1.2" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Breast Invasive Carcinoma (TCGA): 4.6;Glioblastoma Multiforme (TCGA): 6.2;Lung Adenocarcinoma (TCGA): 2.4" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Rhabdoid: 16.0" "Lung - Respiratory ciliated cells" "Region enriched" "Detected in single" 6 "basal ganglia: 1.0" "Low region specificity" "Detected in some" NA NA "Cluster 43: Hindbrain - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" "unprognostic (3.85e-2)" "unprognostic (3.28e-1)" "unprognostic (8.02e-2)" "unprognostic (1.03e-1)" "unprognostic (3.80e-1)" CHRNB1 CHRNB ENSG00000170175 "Cholinergic receptor nicotinic beta 1 subunit" P11230 17 7445061-7457710 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 150.5;tongue: 53.8" "Cell type enhanced" "Detected in some" "Astrocytes: 6.8;Bergmann glia: 7.5;Brain excitatory neurons: 2.1;Brain inhibitory neurons: 2.1;Choroid plexus epithelial cells: 2.7;Distal convoluted tubule cells: 2.3;Ependymal cells: 2.0;Loop of henle epithelial cells: 3.4;Microglia: 3.2;Myosatellite cells: 2.6;Oligodendrocyte progenitor cells: 3.0;Oligodendrocytes: 5.4;Other brain neurons: 3.0;Papillary tip epithelial cells: 3.6;Podocytes: 2.8;Proximal tubule cells: 2.0;Renal collecting duct principal cells: 3.2;Renal connecting tubule cells: 2.6;Thymic myoid cells: 2.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Endothelial cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA005822, CAB011200" Approved NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 8: Immune cells - Immune response" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 98: Neurons - Neurotransmission & signaling" 1 "CAB011200: , HPA005822: " "unprognostic (2.15e-1)" "unprognostic (1.36e-1)" "unprognostic (1.44e-1)" "unprognostic (1.16e-2)" "unprognostic (8.70e-3)" "unprognostic (1.24e-1)" "unprognostic (7.45e-3)" "unprognostic (2.16e-1)" "unprognostic (6.97e-2)" "unprognostic (1.09e-2)" "unprognostic (1.56e-1)" "unprognostic (2.49e-1)" "unprognostic (2.89e-2)" "unprognostic (5.67e-2)" "unprognostic (4.44e-2)" "unprognostic (4.36e-1)" "unprognostic (9.28e-2)" "unprognostic (7.21e-2)" "unprognostic (1.98e-2)" "unprognostic (2.82e-1)" "unprognostic (2.23e-2)" "unprognostic (2.74e-1)" "potential prognostic unfavorable (2.06e-4)" "unprognostic (2.25e-1)" "unprognostic (1.78e-1)" "unprognostic (2.11e-1)" "unprognostic (1.99e-2)" "unprognostic (8.93e-2)" "unprognostic (4.87e-1)" "unprognostic (1.21e-1)" "unprognostic (3.27e-2)" CHRNB2 ENSG00000160716 "Cholinergic receptor nicotinic beta 2 subunit" P17787 1 154567778-154580013 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 13.7;pituitary gland: 3.4;retina: 7.7" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 10.6;Brain excitatory neurons: 6.7;Brain inhibitory neurons: 9.6;Cone photoreceptor cells: 12.4;Corticotrophs: 4.6;Late primary spermatocytes: 6.2;Late spermatids: 22.6;Neuroendocrine cells: 4.3;Other brain neurons: 8.6;Pancreatic islet cells: 8.3;Retinal amacrine cells: 9.7;Retinal bipolar cells: 8.6;Retinal horizontal cells: 14.0" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 3.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 18.9" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Pituitary gland - Corticotropes, Stomach - Gastric enteroendocrine cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 2 "unprognostic (1.98e-1)" "unprognostic (3.23e-1)" "unprognostic (5.52e-3)" "unprognostic (8.35e-3)" "unprognostic (1.77e-1)" CHRNB3 ENSG00000147432 "Cholinergic receptor nicotinic beta 3 subunit" Q05901 8 42697366-42737407 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Group enriched" "Detected in some" 7 "brain: 2.5;pancreas: 1.7;retina: 3.5;testis: 1.2" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 7.7;Epicardial cells: 13.6;Other brain neurons: 5.4;Retinal amacrine cells: 30.0;Retinal ganglion cells: 69.5" "Cell type enhanced" "Detected in many" "mammillary body: 27.8;upper rhombic lip: 32.9" "Cancer enriched" "Detected in single" 4 "Testicular Germ Cell Tumor (TCGA): 1.3" "Group enriched" "Detected in many" 4 "cerebellum: 25.9;midbrain: 22.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 8 "Rhabdoid: 2.2" "Testis - Early spermatids" "Region enhanced" "Detected in many" "midbrain: 6.9" "Low region specificity" "Detected in all" HPA045555 Enhanced NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 2: Neurons - Nucleosome" "Cluster 5: Rhabdoid - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" 3 "HPA045555: " "unprognostic (1.23e-1)" CHRNB4 ENSG00000117971 "Cholinergic receptor nicotinic beta 4 subunit" P30926 15 78624111-78727754 "FDA approved drug targets, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 2.3;lymphoid tissue: 2.7;retina: 2.6;testis: 5.6" "Group enriched" "Detected in some" 4 "Early spermatids: 177.4;Late spermatids: 135.3;Oocytes: 152.0" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 6.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 35 "Neuroblastoma: 34.5" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Group enriched" "Detected in some" 5 "olfactory bulb: 5.3;pons and medulla: 1.4;thalamus: 4.2" HPA059484 Approved "Endoplasmic reticulum,Cell Junctions" NA NA "Cluster 39: Testis - Nuclear processes" "Cluster 46: Brainstem - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" "Endoplasmic reticulum" "Cell Junctions" "HPA059484: " "unprognostic (1.45e-1)" "unprognostic (2.40e-2)" "unprognostic (2.24e-1)" "unprognostic (2.03e-2)" "unprognostic (1.67e-1)" CHRND ACHRD ENSG00000135902 "Cholinergic receptor nicotinic delta subunit" Q07001 2 232525993-232536667 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "skeletal muscle: 75.2" "Group enriched" "Detected in some" 6 "Müller glia: 21.7;Myonuclei: 14.7;Myosatellite cells: 5.6;Thymic myoid cells: 21.8" "Cell type enhanced" "Detected in single" "lower rhombic lip: 1.9" "Cancer enriched" "Detected in single" 5 "Head and Neck Squamous Cell Carcinoma (TCGA): 2.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 27 "Sarcoma: 23.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA065404 Supported "Plasma membrane" NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 7 "Plasma membrane" "HPA065404: " "unprognostic (3.31e-3)" CHRNE ACHRE ENSG00000108556 "Cholinergic receptor nicotinic epsilon subunit" Q04844 17 4897771-4934438 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "heart muscle: 57.6;pituitary gland: 27.7" "Cell type enhanced" "Detected in many" "Corticotrophs: 65.4;Epicardial cells: 88.7;Late spermatids: 301.1;Neutrophils: 59.0;Oocytes: 64.5;Rod photoreceptor cells: 64.4" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.5" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in single" "prostate cancer: 1.3" "Pituitary gland - Corticotropes, Skin - Keratinocyte (granular), Testis - Late spermatids" "Not detected" "Not detected" "Region enriched" "Detected in single" 14 "basal ganglia: 8.3" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 35: Non-specific - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 49: HMC-1 - Innate immune response" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" "unprognostic (1.35e-1)" "unprognostic (2.74e-1)" "unprognostic (1.93e-1)" CHRNG ACHRG ENSG00000196811 "Cholinergic receptor nicotinic gamma subunit" P07510 2 232539692-232548115 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 24 "skeletal muscle: 31.5" "Group enriched" "Detected in some" 12 "Myonuclei: 78.7;Thymic myoid cells: 23.1" "Cell type enhanced" "Detected in single" "hippocampal dentate gyrus: 1.2" "Cancer enhanced" "Detected in single" "Uterine Corpus Endometrial Carcinoma (TCGA): 1.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 21 "Sarcoma: 7.1" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 15: Non-specific - Transcription" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 16 "unprognostic (4.47e-2)" "unprognostic (5.68e-3)" "unprognostic (7.38e-2)" CHST1 "C6ST, KSGal6ST" ENSG00000175264 "Carbohydrate sulfotransferase 1" O43916 11 45647689-45665622 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Inflammatory response" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 41.3" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 42.5;Astrocytes: 61.0;Bergmann glia: 22.7;Brain excitatory neurons: 25.7;Early spermatids: 66.0;Lacrimal acinar cells: 67.0;Late primary spermatocytes: 211.1;Other brain neurons: 24.4;Podocytes: 24.8;Salivary acinar cells: 22.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Spleen - Fibroblasts_1, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060313, HPA072592" Approved Nucleoli,Mitochondria "Intracellular and membrane" Enzyme NA NA 17000 "Cluster 78: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 2 Mitochondria Nucleoli "HPA060313: , HPA072592: " "unprognostic (1.96e-1)" "unprognostic (2.05e-3)" "unprognostic (2.27e-1)" "unprognostic (8.65e-2)" "unprognostic (2.50e-3)" "unprognostic (9.90e-2)" "unprognostic (4.39e-2)" "unprognostic (2.20e-1)" "unprognostic (3.20e-1)" "unprognostic (8.70e-2)" "unprognostic (5.50e-2)" "unprognostic (4.43e-1)" "potential prognostic unfavorable (1.62e-4)" "unprognostic (1.43e-1)" "unprognostic (2.88e-1)" "potential prognostic unfavorable (6.39e-5)" "unprognostic (6.55e-2)" "unprognostic (1.35e-1)" "unprognostic (9.77e-2)" "unprognostic (2.85e-1)" "unprognostic (1.02e-1)" "unprognostic (1.62e-1)" "unprognostic (1.94e-2)" "unprognostic (2.12e-1)" "unprognostic (2.37e-1)" "unprognostic (7.86e-3)" "unprognostic (2.71e-1)" "unprognostic (1.46e-1)" "unprognostic (1.41e-1)" CHST10 HNK-1ST ENSG00000115526 "Carbohydrate sulfotransferase 10" O43529 2 100391860-100417668 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism, Lipid metabolism, Steroid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 29.2;Bergmann glia: 18.9;Pituicytes/FSCs: 24.9" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 39.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012884, HPA051545" Approved Approved Cytosol NA NA 600000 "Cluster 24: Non-specific - Transcription" "Cluster 65: Brain - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 5: Rhabdoid - Unknown function" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 6 Cytosol "HPA012884: , HPA051545: " "unprognostic (1.63e-2)" "unprognostic (3.44e-2)" "unprognostic (2.19e-1)" "unprognostic (5.21e-2)" "unprognostic (8.11e-3)" "unprognostic (1.46e-1)" "unprognostic (2.55e-1)" "unprognostic (7.07e-3)" "unprognostic (1.16e-1)" "unprognostic (1.45e-1)" "unprognostic (1.17e-1)" "unprognostic (1.65e-1)" "unprognostic (1.86e-2)" "unprognostic (3.52e-2)" "unprognostic (2.26e-1)" "unprognostic (3.11e-1)" "unprognostic (1.93e-1)" "unprognostic (1.58e-1)" "potential prognostic favorable (7.50e-4)" "unprognostic (6.70e-2)" "unprognostic (2.74e-1)" "potential prognostic favorable (2.23e-4)" "unprognostic (6.64e-2)" "unprognostic (9.50e-2)" "unprognostic (4.58e-1)" "unprognostic (1.17e-1)" "unprognostic (8.06e-2)" "unprognostic (1.49e-2)" "unprognostic (1.35e-1)" "unprognostic (5.21e-2)" "unprognostic (5.23e-2)" CHST11 "C4ST, C4St-1, C4ST1, HSA269537" ENSG00000171310 "Carbohydrate sulfotransferase 11" Q9NPF2 12 104455295-104762014 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism" Transferase "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 36.7;choroid plexus: 32.8" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 1057.9;Hematopoietic stem cells: 1239.3;Macrophages: 746.0;Megakaryocyte-Erythroid progenitors: 746.2;Microglia: 1430.3;Monocyte progenitors: 820.0;monocytes: 700.9;Neutrophils: 1587.5;NK-cells: 831.1;Oligodendrocyte progenitor cells: 1558.4;Pituicytes/FSCs: 1040.0;T-cells: 729.0;Thymocytes: 858.8" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 1872.3;oligodendrocyte precursor cell: 1638.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 12.8;eosinophil: 11.3;neutrophil: 15.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 15.7" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052828 Approved Approved "Golgi apparatus" NA NA 15000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" "Golgi apparatus" "HPA052828: " "unprognostic (5.12e-2)" "unprognostic (1.15e-1)" "unprognostic (2.83e-1)" "unprognostic (4.46e-3)" "unprognostic (1.65e-1)" "unprognostic (2.33e-1)" "unprognostic (2.57e-1)" "unprognostic (8.39e-2)" "unprognostic (8.23e-2)" "unprognostic (3.24e-2)" "unprognostic (2.56e-3)" "unprognostic (1.35e-1)" "unprognostic (5.06e-3)" "potential prognostic unfavorable (9.98e-4)" "unprognostic (1.70e-1)" "unprognostic (2.75e-2)" "unprognostic (7.58e-3)" "unprognostic (4.69e-2)" "unprognostic (4.80e-3)" "unprognostic (4.13e-2)" "unprognostic (1.17e-2)" "unprognostic (8.85e-3)" "unprognostic (1.39e-3)" "unprognostic (9.79e-2)" "unprognostic (6.97e-3)" "unprognostic (2.23e-1)" "unprognostic (6.56e-2)" "unprognostic (6.64e-2)" "unprognostic (1.38e-1)" "unprognostic (2.11e-2)" "unprognostic (1.11e-1)" CHST12 "C4S-2, C4ST2" ENSG00000136213 "Carbohydrate sulfotransferase 12" Q9NRB3 7 2403588-2448484 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Carbohydrate metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 134.4;NK-cells: 148.4;Syncytiotrophoblasts: 157.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041680 Approved Approved "Golgi apparatus" NA NA 750000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 5: Spleen - Immune response" "Cluster 19: Astrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 24 "Golgi apparatus" "HPA041680: " "unprognostic (3.04e-1)" "unprognostic (3.69e-1)" "unprognostic (2.68e-1)" "unprognostic (7.76e-3)" "unprognostic (1.75e-2)" "unprognostic (1.77e-1)" "unprognostic (1.47e-2)" "unprognostic (5.25e-3)" "unprognostic (5.29e-2)" "unprognostic (8.82e-2)" "unprognostic (1.07e-2)" "unprognostic (8.01e-2)" "unprognostic (1.63e-2)" "unprognostic (4.79e-3)" "unprognostic (5.43e-2)" "unprognostic (7.16e-2)" "unprognostic (1.87e-1)" "unprognostic (9.37e-3)" "unprognostic (1.81e-1)" "unprognostic (6.56e-3)" "unprognostic (8.69e-2)" "unprognostic (5.91e-3)" "unprognostic (6.16e-2)" "unprognostic (8.88e-2)" "unprognostic (3.20e-1)" "unprognostic (1.38e-1)" "unprognostic (1.17e-1)" "unprognostic (6.31e-2)" "unprognostic (3.59e-1)" "unprognostic (5.92e-2)" "unprognostic (3.56e-1)" CHST13 C4ST3 ENSG00000180767 "Carbohydrate sulfotransferase 13" Q8NET6 3 126524155-126543291 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "liver: 54.8;testis: 16.1" "Group enriched" "Detected in some" 4 "Early spermatids: 77.7;Late primary spermatocytes: 290.9" "Cell type enhanced" "Detected in some" "deep-layer intratelencephalic: 1.2;hippocampal CA4: 1.5;hippocampal dentate gyrus: 1.4" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 29.0" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 5 "eosinophil: 155.5" "Lineage enriched" "Detected in many" 5 "granulocytes: 155.5" "Cancer enhanced" "Detected in some" "liver cancer: 14.2" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Minor Salivary Gland - Macrophages, Spleen - Macrophages, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA067960 Approved "Golgi apparatus" "Intracellular and membrane" Enzyme NA NA 9300 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 29: Forebrain - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 1 "Golgi apparatus" "HPA067960: " "unprognostic (6.73e-3)" "unprognostic (7.54e-3)" "unprognostic (1.25e-1)" "unprognostic (1.69e-2)" "unprognostic (4.20e-1)" "unprognostic (2.91e-2)" "unprognostic (5.17e-2)" "unprognostic (3.08e-3)" "unprognostic (6.89e-3)" "unprognostic (1.68e-1)" "unprognostic (1.61e-1)" "unprognostic (3.60e-2)" "unprognostic (1.71e-1)" "unprognostic (8.08e-3)" CHST14 "D4ST-1, D4ST1, HD4ST" ENSG00000169105 "Carbohydrate sulfotransferase 14" Q8NCH0 15 40470984-40473158 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Carbohydrate metabolism" Transferase "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 55.3;Extravillous trophoblasts: 35.9;Migrating cytotrophoblasts: 44.0" "Group enriched" "Detected in some" 4 "astrocyte: 2.9;central nervous system macrophage: 4.2;committed oligodendrocyte precursor: 3.5;endothelial cell: 6.5;ependymal cell: 4.7;fibroblast: 6.9;leukocyte: 3.9;oligodendrocyte precursor cell: 4.7;pericyte: 8.0;vascular associated smooth muscle cell: 7.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 7.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Adrenal gland - Fibroblasts, Breast - Fibroblasts, Prostate - Fibroblasts, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057697, HPA071601" Enhanced Approved "Golgi apparatus" NA NA 13000 "Cluster 45: Eosinophils - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 44: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 25 "Golgi apparatus" "HPA057697: , HPA071601: " "unprognostic (5.09e-2)" "unprognostic (1.41e-1)" "unprognostic (2.34e-1)" "unprognostic (9.30e-2)" "unprognostic (4.70e-2)" "unprognostic (1.89e-1)" "unprognostic (9.74e-2)" "unprognostic (1.20e-2)" "unprognostic (5.67e-2)" "unprognostic (1.66e-1)" "unprognostic (2.91e-2)" "unprognostic (7.67e-2)" "unprognostic (3.94e-2)" "unprognostic (1.54e-1)" "unprognostic (4.53e-3)" "unprognostic (3.09e-2)" "unprognostic (1.57e-2)" "unprognostic (3.85e-1)" "unprognostic (8.26e-3)" "unprognostic (2.25e-2)" "unprognostic (4.06e-1)" "unprognostic (2.82e-1)" "unprognostic (1.87e-1)" "unprognostic (6.23e-2)" "unprognostic (5.73e-3)" "unprognostic (6.01e-2)" "unprognostic (1.24e-1)" "unprognostic (2.24e-3)" "unprognostic (1.66e-1)" "unprognostic (8.58e-3)" "unprognostic (1.55e-1)" CHST15 "BRAG, GALNAC4S-6ST, KIAA0598" ENSG00000182022 "Carbohydrate sulfotransferase 15" Q7LFX5 10 124007668-124093598 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 185.1;Lymphatic endothelial cells: 201.1;monocytes: 350.4;Neutrophils: 1082.6;Plasma cells: 150.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 69.2" "Group enriched" "Detected in many" 11 "granulocytes: 69.2;monocytes: 38.9" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Pituitary gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017584 Approved Approved Centrosome,Cytosol NA NA 400000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 23: Choroid plexus - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 3 Cytosol Centrosome "HPA017584: " "unprognostic (1.44e-1)" "unprognostic (1.13e-1)" "unprognostic (4.72e-1)" "unprognostic (5.87e-3)" "unprognostic (4.69e-1)" "unprognostic (3.67e-1)" "unprognostic (5.66e-2)" "unprognostic (1.49e-1)" "unprognostic (3.62e-2)" "unprognostic (4.65e-3)" "unprognostic (3.71e-1)" "unprognostic (2.08e-1)" "unprognostic (9.22e-3)" "unprognostic (1.25e-1)" "unprognostic (7.26e-2)" "unprognostic (7.26e-2)" "unprognostic (1.03e-2)" "unprognostic (1.14e-2)" "unprognostic (4.78e-3)" "unprognostic (1.40e-2)" "potential prognostic unfavorable (1.53e-4)" "unprognostic (3.29e-2)" "unprognostic (8.65e-3)" "unprognostic (3.38e-2)" "unprognostic (7.45e-2)" "unprognostic (9.72e-2)" "unprognostic (4.25e-2)" "unprognostic (5.28e-2)" "unprognostic (1.21e-1)" "unprognostic (5.08e-2)" "unprognostic (5.41e-2)" CHST2 C6ST ENSG00000175040 "Carbohydrate sulfotransferase 2" Q9Y4C5 3 143119771-143124014 "Metabolic proteins, Predicted membrane proteins" "Carbohydrate metabolism, Inflammatory response" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 49.8" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 67.0;Epididymal clear cells: 59.2;Müller glia: 96.4;NK-cells: 39.8;Pericytes: 32.0;Pituicytes/FSCs: 24.6;Plasma cells: 65.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 4.3;NK-cell: 4.9;non-classical monocyte: 11.4" "Group enriched" "Detected in many" 5 "monocytes: 11.4;NK-cells: 4.9" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013620 Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 27: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 44: Plasma cells - Antibody production & secretion" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA013620: " "unprognostic (3.22e-1)" "unprognostic (3.40e-2)" "unprognostic (9.34e-2)" "unprognostic (3.89e-1)" "unprognostic (7.60e-2)" "unprognostic (2.23e-1)" "unprognostic (2.82e-2)" "potential prognostic unfavorable (1.18e-4)" "unprognostic (2.56e-1)" "unprognostic (4.04e-1)" "unprognostic (6.54e-2)" "unprognostic (1.05e-1)" "unprognostic (1.11e-2)" "unprognostic (3.82e-2)" "unprognostic (1.44e-1)" "unprognostic (5.07e-2)" "unprognostic (5.26e-2)" "unprognostic (4.66e-2)" "unprognostic (5.88e-2)" "unprognostic (3.10e-2)" "unprognostic (2.43e-1)" "unprognostic (3.17e-3)" "unprognostic (2.08e-1)" "unprognostic (7.58e-2)" "unprognostic (1.72e-1)" "unprognostic (5.38e-2)" "unprognostic (2.66e-1)" "unprognostic (9.26e-2)" "unprognostic (1.27e-1)" "unprognostic (1.86e-2)" "unprognostic (1.59e-1)" CHST3 "C6ST, C6ST1" ENSG00000122863 "Carbohydrate sulfotransferase 3" Q7LGC8 10 71964395-72013558 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Carbohydrate metabolism" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 50.1;Ependymal cells: 49.3;Oligodendrocytes: 55.0;Schwann cells: 64.9;Sertoli cells: 53.0" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 74.7;ependymal cell: 51.9;oligodendrocyte: 63.5;oligodendrocyte precursor cell: 54.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Macrophages, Pituitary gland - Endothelial cells, Spleen - Fibroblasts_1, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA047523, HPA055704" Enhanced Approved "Golgi apparatus,Cytosol" NA NA 950000 "Cluster 21: Testis - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 61: Schwann cells & Melanocytes - Mixed function" 1 "Golgi apparatus, Cytosol" "HPA047523: , HPA055704: " "unprognostic (1.07e-1)" "unprognostic (3.82e-2)" "unprognostic (4.56e-1)" "unprognostic (1.32e-2)" "unprognostic (1.06e-2)" "unprognostic (4.17e-3)" "unprognostic (4.12e-2)" "unprognostic (1.15e-3)" "unprognostic (8.68e-2)" "unprognostic (1.01e-1)" "unprognostic (5.36e-2)" "unprognostic (1.61e-1)" "unprognostic (1.32e-1)" "unprognostic (3.90e-2)" "unprognostic (2.32e-1)" "unprognostic (1.10e-1)" "unprognostic (2.21e-2)" "unprognostic (1.07e-1)" "unprognostic (3.46e-1)" "unprognostic (4.29e-2)" "unprognostic (2.07e-2)" "unprognostic (1.71e-2)" "unprognostic (1.08e-2)" "unprognostic (6.20e-2)" "unprognostic (1.11e-1)" "unprognostic (3.99e-2)" "unprognostic (7.38e-2)" "unprognostic (7.61e-3)" "unprognostic (7.79e-2)" "unprognostic (4.17e-3)" "unprognostic (2.12e-2)" CHST4 "HEC-GLCNAC-6-ST, LSST" ENSG00000140835 "Carbohydrate sulfotransferase 4" Q8NCG5 16 71525233-71538748 "Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Inflammatory response" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "gallbladder: 65.2" "Cell type enriched" "Detected in some" 9 "Cholangiocytes: 268.5" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 5.6;ependymal cell: 10.1" "Cancer enriched" "Detected in many" 7 "Pancreatic Adenocarcinoma (TCGA): 17.8" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 13.1;pancreatic cancer: 6.4" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal cortex cells, Liver - Cholangiocytes, Prostate - Prostate basal glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA021955 Enhanced NA NA "Cluster 13: Lung - Secretion" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 38: Secretory epithelial cells - Exocrine secretion" "HPA021955: " "unprognostic (1.00e-2)" "unprognostic (1.71e-1)" "unprognostic (1.77e-1)" "unprognostic (1.66e-2)" "unprognostic (4.48e-3)" "unprognostic (1.19e-1)" "unprognostic (1.28e-2)" "unprognostic (2.06e-1)" "unprognostic (8.21e-2)" "unprognostic (6.57e-3)" "unprognostic (2.03e-1)" "unprognostic (2.42e-1)" "unprognostic (2.60e-2)" "unprognostic (1.99e-2)" "unprognostic (6.21e-2)" "unprognostic (8.80e-2)" CHST5 "FLJ22167, I-GLCNAC-6-ST" ENSG00000135702 "Carbohydrate sulfotransferase 5" Q9GZS9 16 75528530-75536108 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "intestine: 82.2" "Cell type enhanced" "Detected in some" "Colonocytes: 27.3;Enteric stem cells: 8.2;Enteric transient amplifying cells: 10.9;Enterocytes: 26.8;Ependymal cells: 13.8;Foveolar cells: 6.3;Goblet cells: 25.4;Neuroendocrine cells: 8.5" "Cell type enhanced" "Detected in many" "ependymal cell: 16.5" "Group enriched" "Detected in some" 6 "Colon Adenocarcinoma (TCGA): 14.6;Rectum Adenocarcinoma (TCGA): 14.9;Stomach Adenocarcinoma (TCGA): 13.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 2.4" "Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells" "HPA043804, HPA068029" Enhanced NA NA "Cluster 77: Intestine - Digestion" "Cluster 17: Choroid plexus - Cilium" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" "HPA043804: , HPA068029: " "unprognostic (1.93e-2)" "unprognostic (3.59e-3)" "unprognostic (1.03e-3)" "unprognostic (1.15e-1)" "unprognostic (1.07e-2)" "unprognostic (1.96e-1)" "unprognostic (3.72e-2)" "unprognostic (3.39e-3)" "unprognostic (3.77e-1)" CHST6 MCDC1 ENSG00000183196 "Carbohydrate sulfotransferase 6" Q9GZX3 16 75472052-75495445 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism" Transferase "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 4.2;brain: 7.4;cervix: 8.9" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 29.1;Endometrial ciliated cells: 90.3;Endometrial secretory cells: 53.8;Ependymal cells: 44.2;Esophageal apical cells: 20.5;Fallopian tube ciliated cells: 24.9;Oligodendrocytes: 20.1;Respiratory basal cells: 21.7;Respiratory ciliated cells: 77.0;Respiratory deuterosomal cells: 27.0;Respiratory secretory cells: 41.7" "Cell type enhanced" "Detected in many" "astrocyte: 28.7;ependymal cell: 51.3;oligodendrocyte: 23.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 6.8" "Adrenal gland - Adrenal cortex cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells" HPA068029 Approved "Intracellular and membrane" Enzyme NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 38: Secretory epithelial cells - Exocrine secretion" "HPA068029: " "unprognostic (2.89e-1)" "unprognostic (9.56e-3)" "unprognostic (1.14e-1)" "unprognostic (3.23e-2)" "unprognostic (7.84e-2)" "unprognostic (1.24e-3)" "unprognostic (1.39e-2)" "unprognostic (3.67e-2)" "unprognostic (8.83e-3)" "unprognostic (3.67e-2)" "unprognostic (5.06e-1)" "unprognostic (2.17e-2)" "unprognostic (1.93e-1)" "unprognostic (1.10e-1)" "unprognostic (2.94e-3)" "unprognostic (4.37e-2)" "unprognostic (9.84e-2)" "unprognostic (3.07e-2)" "unprognostic (8.79e-2)" "unprognostic (5.05e-2)" CHST7 "C6ST-2, C6ST2" ENSG00000147119 "Carbohydrate sulfotransferase 7" Q9NS84 X 46573765-46598496 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 32.0" "Cell type enhanced" "Detected in many" "Bergmann glia: 36.2;Cardiomyocytes: 41.1;Decidual stromal cells: 42.4;Fibroblasts: 35.3;monocytes: 47.4;Myosatellite cells: 59.3;Ovarian stromal cells: 57.5;Peritubular myoid cells: 58.0" "Cell type enhanced" "Detected in all" "Bergmann glia: 49.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 18.6" "Group enriched" "Detected in many" 10 "granulocytes: 10.9;monocytes: 10.3;T-cells: 18.6" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Kidney - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA003919, HPA030503" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 75: Ovary - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 5: Rhabdoid - Unknown function" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" "Nucleoplasm, Vesicles" "HPA003919: , HPA030503: " "unprognostic (1.17e-1)" "unprognostic (3.68e-2)" "unprognostic (8.98e-2)" "unprognostic (8.96e-2)" "unprognostic (1.48e-1)" "unprognostic (3.17e-2)" "unprognostic (2.32e-1)" "unprognostic (3.30e-2)" "unprognostic (5.28e-2)" "unprognostic (1.34e-1)" "potential prognostic favorable (2.09e-4)" "unprognostic (4.10e-2)" "unprognostic (4.70e-2)" "unprognostic (5.28e-2)" "unprognostic (1.69e-3)" "unprognostic (4.34e-2)" "unprognostic (1.58e-1)" "unprognostic (8.09e-3)" "unprognostic (1.18e-2)" "unprognostic (1.25e-1)" "unprognostic (1.43e-1)" "unprognostic (4.95e-3)" "unprognostic (1.14e-1)" "unprognostic (6.01e-2)" "unprognostic (6.79e-2)" "unprognostic (3.13e-1)" "unprognostic (3.98e-2)" "unprognostic (1.41e-2)" "unprognostic (9.65e-2)" "unprognostic (1.36e-1)" "unprognostic (1.84e-1)" CHST8 GALNAC4ST-1 ENSG00000124302 "Carbohydrate sulfotransferase 8" Q9H2A9 19 33621953-33773509 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 21 "brain: 17.4;pituitary gland: 61.4" "Cell type enhanced" "Detected in many" "Corticotrophs: 157.8;Gonadotrophs: 217.8;Granulosa cells: 66.5;Lactotrophs: 473.0;Late spermatids: 132.7;Platelets: 69.1;Retinal ganglion cells: 123.6;Somatotrophs: 340.7;Thyrotrophs: 126.5" "Cell type enhanced" "Detected in many" "lower rhombic lip: 181.8" "Group enriched" "Detected in some" 4 "Breast Invasive Carcinoma (TCGA): 9.1;Glioblastoma Multiforme (TCGA): 11.8;Testicular Germ Cell Tumor (TCGA): 6.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Neuroblastoma: 12.0" "Adrenal gland - Adrenal medulla cells, Pancreas - Beta cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA016004 Enhanced "Intracellular and membrane" Enzyme NA NA "Cluster 65: Brain - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 42 "HPA016004: " "unprognostic (8.38e-3)" "unprognostic (1.75e-1)" "unprognostic (3.22e-1)" "unprognostic (5.64e-2)" "unprognostic (9.59e-2)" "unprognostic (1.76e-2)" "unprognostic (2.08e-2)" "unprognostic (2.49e-1)" CHST9 "GALNAC-4-ST2, GALNAC4ST-2" ENSG00000154080 "Carbohydrate sulfotransferase 9" Q7L1S5 18 26906481-27185308 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 12.6" "Cell type enhanced" "Detected in many" "Prostatic hillock cells: 455.5;Respiratory basal cells: 1717.1;Respiratory ciliated cells: 1789.2;Respiratory deuterosomal cells: 2151.0;Respiratory secretory cells: 2028.0;Salivary basal cells: 468.2;Submucosal glandular cells: 510.6" "Cell type enhanced" "Detected in many" "hippocampal dentate gyrus: 365.6;LAMP5-LHX6 and Chandelier: 782.2;oligodendrocyte precursor cell: 425.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 5.9;liver cancer: 10.6" "Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Pituitary gland - Thyrotropes, Testis - Sertoli cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA011393 Uncertain "Intracellular and membrane" Enzyme NA NA "Cluster 82: Salivary gland - Secretion" "Cluster 29: Forebrain - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 3 "HPA011393: " "unprognostic (1.97e-2)" "unprognostic (4.45e-1)" "unprognostic (3.06e-2)" "unprognostic (1.33e-2)" "potential prognostic favorable (3.07e-4)" "potential prognostic favorable (1.49e-4)" "unprognostic (5.23e-3)" "unprognostic (7.46e-2)" "unprognostic (1.18e-2)" "unprognostic (9.33e-2)" "unprognostic (9.90e-2)" "unprognostic (1.49e-2)" "unprognostic (3.34e-3)" "unprognostic (2.04e-1)" "unprognostic (1.80e-1)" "unprognostic (1.24e-1)" "unprognostic (9.40e-3)" "unprognostic (3.01e-2)" "unprognostic (3.17e-2)" "unprognostic (3.34e-1)" "unprognostic (1.83e-1)" CHSY1 "CSS1, KIAA0990" ENSG00000131873 "Chondroitin sulfate synthase 1" Q86X52 15 101175727-101252048 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" Transferase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 267.5;Neutrophil progenitors: 216.5;Neutrophils: 633.7" "Cell type enhanced" "Detected in all" "endothelial cell: 350.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" Enzyme NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 12: Non-specific - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 2 "unprognostic (1.20e-2)" "unprognostic (1.16e-1)" "unprognostic (3.32e-2)" "unprognostic (1.83e-1)" "unprognostic (3.57e-1)" "unprognostic (1.22e-1)" "unprognostic (1.05e-1)" "unprognostic (7.54e-2)" "unprognostic (3.41e-3)" "unprognostic (7.64e-2)" "unprognostic (5.40e-2)" "unprognostic (1.11e-1)" "unprognostic (1.19e-1)" "unprognostic (1.15e-1)" "unprognostic (1.42e-2)" "unprognostic (5.79e-2)" "unprognostic (1.70e-3)" "unprognostic (1.03e-1)" "unprognostic (1.76e-1)" "unprognostic (2.58e-1)" "unprognostic (2.16e-2)" "unprognostic (3.92e-2)" "unprognostic (5.63e-2)" "unprognostic (1.13e-1)" "unprognostic (1.45e-2)" "unprognostic (2.45e-1)" "unprognostic (3.49e-1)" "unprognostic (3.61e-2)" "unprognostic (3.79e-1)" "potential prognostic unfavorable (2.63e-4)" "unprognostic (2.41e-1)" CHSY3 "CHSY-2, CSS3" ENSG00000198108 "Chondroitin sulfate synthase 3" Q70JA7 5 129904465-130186634 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 10.0" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 502.9;Brain inhibitory neurons: 480.4;Decidual stromal cells: 201.5;Endometrial stromal cells: 758.9;Hepatic stellate cells: 180.7;Lymphatic endothelial cells: 184.8;Melanocytes: 411.6;Microglia: 262.6;Other brain neurons: 188.4;Pericytes: 282.0;Transitional alveolar cells: 190.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Breast - Endothelial cells, Minor Salivary Gland - Endothelial cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA044612 Uncertain NA NA 3600 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 51: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 35: Neurons - Synaptic function & neurogenesis" 6 "HPA044612: " "unprognostic (3.24e-1)" "unprognostic (4.11e-2)" "unprognostic (3.45e-2)" "unprognostic (4.19e-1)" "unprognostic (1.10e-1)" "unprognostic (1.19e-1)" "unprognostic (1.68e-1)" "unprognostic (1.63e-1)" "unprognostic (9.41e-2)" "unprognostic (1.72e-1)" "unprognostic (3.93e-2)" "unprognostic (5.36e-2)" "unprognostic (4.20e-1)" "unprognostic (9.83e-2)" "unprognostic (1.36e-1)" "unprognostic (1.22e-2)" "unprognostic (3.15e-1)" "unprognostic (1.67e-3)" CHTF18 "C16orf41, C321D2.4, CHL12, Ctf18" ENSG00000127586 "Chromosome transmission fidelity factor 18" Q8WVB6 16 788046-800737 "Predicted intracellular proteins" "Cell cycle, DNA replication" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 25.0;Erythrocyte progenitors: 21.3;Extravillous trophoblasts: 23.3;Migrating cytotrophoblasts: 21.3;Oocytes: 18.4;Retinal bipolar cells: 25.5;Undifferentiated spermatogonia: 20.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "basophil: 2.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA040976, HPA056209" Supported Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 67: Testis - Mixed function" "Cluster 34: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 11 Nucleoplasm Cytosol "HPA040976: , HPA056209: " "potential prognostic unfavorable (7.44e-4)" "unprognostic (3.23e-1)" "unprognostic (3.35e-1)" "unprognostic (5.97e-2)" "unprognostic (7.53e-2)" "unprognostic (1.78e-2)" "unprognostic (2.74e-1)" "unprognostic (5.17e-3)" "unprognostic (2.77e-2)" "unprognostic (8.78e-2)" "unprognostic (1.50e-3)" "potential prognostic unfavorable (9.33e-4)" "unprognostic (1.38e-1)" "potential prognostic unfavorable (8.51e-4)" "unprognostic (1.35e-2)" "potential prognostic unfavorable (5.57e-5)" "unprognostic (3.43e-1)" "unprognostic (4.15e-2)" "unprognostic (1.09e-1)" "unprognostic (1.40e-1)" "unprognostic (6.85e-2)" "unprognostic (1.86e-3)" "unprognostic (8.73e-3)" "unprognostic (4.92e-2)" "unprognostic (3.03e-2)" "unprognostic (1.27e-1)" "unprognostic (2.12e-2)" "unprognostic (1.92e-1)" "unprognostic (1.59e-1)" "unprognostic (2.20e-1)" CHTF8 "CTF8, FLJ20400" ENSG00000168802 "Chromosome transmission fidelity factor 8" P0CG13 16 69118010-69132588 "Predicted intracellular proteins" "Cell cycle, DNA replication" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 40.3;Distal convoluted tubule cells: 24.0;Ependymal cells: 19.9;Loop of henle epithelial cells: 23.7;Microglia: 19.9;Oligodendrocytes: 17.1;Papillary tip epithelial cells: 21.7;Podocytes: 30.7;Proximal tubule cells: 47.3;Renal collecting duct intercalated cells: 24.7;Renal collecting duct principal cells: 15.8;Renal connecting tubule cells: 20.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 72: Kidney - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 102: Non-specific - Mixed function" 7 "unprognostic (1.35e-1)" "unprognostic (3.03e-2)" "unprognostic (1.23e-2)" "unprognostic (2.10e-1)" "unprognostic (3.69e-2)" "unprognostic (1.49e-1)" "unprognostic (1.85e-2)" "unprognostic (7.29e-3)" "unprognostic (2.64e-1)" "unprognostic (5.61e-2)" "validated prognostic favorable (1.39e-8)" "validated prognostic favorable (8.28e-6)" "unprognostic (1.50e-3)" "unprognostic (1.04e-1)" "unprognostic (9.64e-2)" "unprognostic (1.15e-2)" "unprognostic (6.34e-2)" "unprognostic (1.81e-1)" "unprognostic (1.98e-1)" "unprognostic (2.69e-1)" "unprognostic (1.76e-2)" "unprognostic (1.02e-2)" "unprognostic (1.50e-1)" "unprognostic (1.32e-1)" "unprognostic (2.24e-1)" "unprognostic (4.79e-2)" "unprognostic (1.87e-1)" "unprognostic (1.37e-1)" "unprognostic (2.59e-1)" "unprognostic (1.15e-1)" "unprognostic (3.18e-3)" CHTOP "C1orf77, DKFZP547E1010, FOP, SRAG" ENSG00000160679 "Chromatin target of PRMT1" Q9Y3Y2 1 153633982-153646306 "Plasma proteins, Predicted intracellular proteins" "mRNA transport, Transcription, Transcription regulation, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028647, HPA030540" Approved Supported "Nuclear speckles" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 24: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 97: Non-specific - Cellular respiration" 59 "Nuclear speckles" "HPA028647: , HPA030540: " "unprognostic (1.53e-1)" "unprognostic (6.25e-2)" "unprognostic (2.28e-2)" "unprognostic (2.37e-1)" "unprognostic (3.79e-2)" "unprognostic (1.99e-1)" "unprognostic (1.87e-2)" "unprognostic (1.55e-1)" "unprognostic (5.77e-3)" "unprognostic (2.87e-1)" "unprognostic (1.86e-1)" "unprognostic (4.02e-2)" "potential prognostic unfavorable (2.10e-6)" "unprognostic (1.43e-1)" "unprognostic (1.36e-2)" "unprognostic (1.11e-2)" "unprognostic (1.19e-1)" "unprognostic (3.59e-2)" "unprognostic (1.47e-1)" "unprognostic (2.75e-1)" "unprognostic (6.89e-2)" "unprognostic (1.67e-2)" "potential prognostic unfavorable (9.05e-4)" "unprognostic (1.11e-1)" "unprognostic (3.04e-2)" "potential prognostic unfavorable (2.81e-4)" "unprognostic (1.82e-1)" "unprognostic (1.01e-1)" "unprognostic (3.12e-1)" "unprognostic (7.82e-2)" CHUK "IkBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16" ENSG00000213341 "Component of inhibitor of nuclear factor kappa B kinase complex" O15111 10 100188300-100229596 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophil progenitors: 84.0;Neutrophils: 140.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001402, CAB004240, CAB018564" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 52: Non-specific - Mitochondria" "Cluster 24: Neutrophils - Innate immunity signal integration" 120 Nucleoplasm Cytosol "CAB004240: , CAB018564: , HPA001402: " "unprognostic (6.24e-2)" "unprognostic (2.08e-3)" "unprognostic (1.39e-1)" "unprognostic (1.13e-1)" "unprognostic (1.38e-1)" "unprognostic (3.12e-1)" "unprognostic (1.98e-1)" "potential prognostic favorable (2.79e-4)" "unprognostic (1.37e-1)" "unprognostic (9.46e-2)" "potential prognostic favorable (9.25e-9)" "unprognostic (2.79e-2)" "unprognostic (2.49e-1)" "unprognostic (2.32e-2)" "unprognostic (1.20e-1)" "unprognostic (2.48e-2)" "unprognostic (1.40e-1)" "unprognostic (3.95e-1)" "unprognostic (2.12e-1)" "unprognostic (2.98e-2)" "potential prognostic unfavorable (3.35e-5)" "unprognostic (9.88e-2)" "unprognostic (4.98e-2)" "unprognostic (1.95e-1)" "unprognostic (1.69e-1)" "unprognostic (6.83e-2)" "unprognostic (2.41e-1)" "unprognostic (2.04e-1)" "unprognostic (2.26e-1)" "unprognostic (1.47e-3)" "unprognostic (1.33e-1)" CHURC1 "C14orf52, FLJ33064, My015" ENSG00000258289 "Churchill domain containing 1" Q8WUH1 14 64914361-64944591 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric chief cells: 134.3;Hepatocytes: 120.4;Late primary spermatocytes: 160.6;Parietal cells: 274.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040072 Approved Approved Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 97: Non-specific - Cellular respiration" 5 Cytosol "HPA040072: " "unprognostic (1.66e-2)" "unprognostic (2.04e-1)" "unprognostic (1.08e-1)" "unprognostic (1.36e-1)" "unprognostic (4.04e-2)" "unprognostic (1.65e-1)" "unprognostic (1.33e-1)" "potential prognostic unfavorable (1.01e-4)" "potential prognostic unfavorable (4.51e-4)" "potential prognostic unfavorable (1.88e-4)" "potential prognostic favorable (3.08e-7)" "unprognostic (8.68e-3)" "unprognostic (5.07e-2)" "unprognostic (1.35e-2)" "unprognostic (1.24e-1)" "unprognostic (1.28e-3)" "unprognostic (2.30e-1)" "unprognostic (5.58e-2)" "unprognostic (1.13e-1)" "unprognostic (1.17e-1)" "unprognostic (2.36e-3)" "unprognostic (5.81e-3)" "unprognostic (2.15e-1)" "unprognostic (1.91e-2)" "unprognostic (2.44e-1)" "unprognostic (2.94e-1)" "unprognostic (6.32e-2)" "potential prognostic unfavorable (4.39e-4)" "unprognostic (1.34e-1)" "unprognostic (4.60e-3)" "unprognostic (2.85e-2)" CHURC1-FNTB ENSG00000125954 "CHURC1-FNTB readthrough" 14 64914485-65061803 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 58.7;Retinal ganglion cells: 69.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" CAB009260 Uncertain NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 30: White matter - Myelination" "Cluster 69: Skin cancer - ECM organization" "Cluster 24: Neutrophils - Innate immunity signal integration" "CAB009260: " "unprognostic (2.45e-1)" "unprognostic (4.80e-2)" "unprognostic (1.25e-1)" "unprognostic (5.86e-2)" "unprognostic (2.00e-1)" "unprognostic (3.11e-1)" CIAO1 "CIA1, WDR39" ENSG00000144021 "Cytosolic iron-sulfur assembly component 1" O76071 2 96266159-96274173 "Essential proteins, Predicted intracellular proteins" "Chromosome partition" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017882 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 76: Non-specific - Metabolism" "Cluster 27: Non-specific - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 7: Non-specific - Transcription" 75 Nucleoplasm Cytosol "HPA017882: " "unprognostic (6.04e-2)" "unprognostic (5.78e-3)" "unprognostic (3.11e-1)" "unprognostic (1.02e-2)" "unprognostic (4.10e-2)" "unprognostic (1.45e-1)" "unprognostic (6.39e-2)" "potential prognostic favorable (8.72e-5)" "unprognostic (5.19e-2)" "unprognostic (1.53e-3)" "potential prognostic favorable (2.25e-5)" "unprognostic (3.49e-2)" "unprognostic (1.06e-1)" "potential prognostic unfavorable (2.00e-6)" "unprognostic (4.52e-3)" "unprognostic (1.09e-1)" "unprognostic (4.05e-1)" "unprognostic (1.01e-1)" "unprognostic (4.01e-2)" "unprognostic (4.18e-1)" "unprognostic (3.01e-2)" "unprognostic (3.18e-1)" "unprognostic (1.36e-1)" "unprognostic (7.56e-2)" "unprognostic (1.32e-1)" "unprognostic (1.52e-1)" "unprognostic (3.32e-1)" "unprognostic (2.03e-2)" "unprognostic (1.99e-1)" "unprognostic (9.30e-2)" "unprognostic (3.60e-1)" CIAO2A "CIA2A, FAM96A, FLJ22875" ENSG00000166797 "Cytosolic iron-sulfur assembly component 2A" Q9H5X1 15 64072565-64093857 "Predicted intracellular proteins" "Chromosome partition" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 245.2" "Cell type enhanced" "Detected in all" "Hepatocytes: 268.9;Hofbauer cells: 221.1;Kupffer cells: 189.6;Parietal cells: 247.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040459, HPA063729" Approved Enhanced Nucleoplasm,Cytosol "Intracellular and membrane" Other No No "Cluster 23: B-cells - Immunoglobulins" "Cluster 76: Non-specific - Metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 58: Non-specific - Nuclear processes" "Cluster 97: Non-specific - Cellular respiration" 113 "Nucleoplasm, Cytosol" "HPA040459: , HPA063729: " "unprognostic (2.49e-2)" "unprognostic (1.04e-1)" "unprognostic (1.37e-1)" "unprognostic (2.62e-1)" "unprognostic (6.48e-2)" "unprognostic (1.14e-2)" "unprognostic (3.74e-2)" "unprognostic (3.64e-2)" "unprognostic (6.51e-3)" "potential prognostic favorable (1.59e-6)" "unprognostic (2.19e-2)" "unprognostic (3.13e-1)" "unprognostic (5.97e-3)" "unprognostic (4.79e-2)" "unprognostic (2.81e-1)" "unprognostic (8.52e-3)" "unprognostic (2.00e-1)" "unprognostic (2.59e-1)" "unprognostic (1.97e-1)" "unprognostic (2.67e-1)" "unprognostic (3.08e-2)" "potential prognostic unfavorable (9.25e-4)" "unprognostic (8.39e-3)" "unprognostic (2.44e-1)" "unprognostic (4.26e-2)" "unprognostic (1.62e-1)" "unprognostic (1.96e-1)" "unprognostic (1.75e-1)" "unprognostic (1.45e-1)" CIAO2B "CGI-128, CIA2B, FAM96B, MIP18" ENSG00000166595 "Cytosolic iron-sulfur assembly component 2B" Q9Y3D0 16 66932065-66934423 "Essential proteins, Predicted intracellular proteins" "Chromosome partition" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1046.3;Esophageal basal cells: 503.9;Esophageal suprabasal cells: 997.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041501, HPA041736" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 85: Squamous epithelial cells - Keratinization" 39 "Nucleoplasm, Cytosol" "HPA041501: , HPA041736: " "unprognostic (1.59e-2)" "unprognostic (8.43e-2)" "unprognostic (1.59e-1)" "unprognostic (1.04e-1)" "unprognostic (9.38e-2)" "unprognostic (2.58e-1)" "unprognostic (9.72e-2)" "unprognostic (5.61e-3)" "unprognostic (3.33e-2)" "unprognostic (3.62e-2)" "unprognostic (2.31e-1)" "unprognostic (6.37e-2)" "unprognostic (1.04e-2)" "unprognostic (3.35e-1)" "unprognostic (6.57e-2)" "unprognostic (2.04e-2)" "unprognostic (2.68e-1)" "unprognostic (1.91e-1)" "unprognostic (2.23e-1)" "unprognostic (6.61e-2)" "unprognostic (1.59e-1)" "unprognostic (1.59e-2)" "unprognostic (3.43e-1)" "unprognostic (7.64e-2)" "unprognostic (1.07e-1)" "unprognostic (1.61e-1)" "unprognostic (2.98e-1)" "unprognostic (1.39e-1)" "unprognostic (1.11e-1)" CIAO3 "FLJ21988, HPRN, IOP1, NAR1, NARFL, PRN" ENSG00000103245 "Cytosolic iron-sulfur assembly component 3" Q9H6Q4 16 729760-741329 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040851 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 9 Cytosol "Plasma membrane" "HPA040851: " "unprognostic (7.37e-2)" "unprognostic (2.93e-3)" "potential prognostic favorable (1.35e-5)" "unprognostic (1.67e-2)" "unprognostic (5.15e-3)" "unprognostic (1.75e-1)" "unprognostic (3.22e-2)" "unprognostic (8.66e-3)" "unprognostic (2.56e-1)" "unprognostic (3.04e-3)" "unprognostic (2.71e-1)" "unprognostic (5.60e-3)" "potential prognostic unfavorable (4.67e-4)" "unprognostic (1.25e-1)" "unprognostic (6.94e-2)" "unprognostic (1.26e-1)" "unprognostic (6.08e-2)" "unprognostic (7.70e-3)" "unprognostic (3.55e-1)" "unprognostic (2.45e-2)" "unprognostic (1.23e-1)" "unprognostic (9.67e-2)" "unprognostic (1.06e-2)" "unprognostic (1.09e-1)" "unprognostic (1.05e-1)" "unprognostic (1.83e-1)" "unprognostic (3.01e-1)" "unprognostic (1.44e-1)" "unprognostic (2.18e-1)" CIAPIN1 CIAE2 ENSG00000005194 "Cytokine induced apoptosis inhibitor 1" Q6FI81 16 57428187-57447420 "Essential proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 117.9;Early primary spermatocytes: 155.2;Late primary spermatocytes: 356.4;Oocytes: 142.8;Syncytiotrophoblasts: 132.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041350, HPA042182" Enhanced Supported Nucleoplasm,Mitochondria No No 20000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 39: Testis - Nuclear processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 17 Mitochondria Nucleoplasm "HPA041350: , HPA042182: " "unprognostic (3.30e-2)" "unprognostic (1.53e-3)" "unprognostic (2.97e-3)" "unprognostic (2.66e-2)" "unprognostic (4.39e-3)" "unprognostic (1.56e-1)" "unprognostic (5.02e-3)" "potential prognostic favorable (2.52e-4)" "potential prognostic unfavorable (4.22e-5)" "unprognostic (6.42e-2)" "potential prognostic favorable (2.31e-5)" "unprognostic (1.89e-1)" "potential prognostic favorable (2.23e-4)" "potential prognostic unfavorable (2.96e-6)" "unprognostic (3.31e-3)" "unprognostic (1.66e-2)" "unprognostic (1.36e-2)" "unprognostic (1.48e-1)" "unprognostic (2.51e-1)" "unprognostic (2.99e-2)" "unprognostic (1.76e-1)" "unprognostic (7.16e-2)" "unprognostic (1.45e-2)" "unprognostic (5.31e-2)" "unprognostic (2.13e-1)" "unprognostic (1.11e-1)" "unprognostic (1.78e-1)" "unprognostic (2.35e-1)" "unprognostic (4.86e-2)" "unprognostic (9.04e-3)" "unprognostic (5.87e-2)" CIART "BC017397, C1orf51, CHRONO" ENSG00000159208 "Circadian associated repressor of transcription" Q8N365 1 150282543-150287093 "Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 45.5;Epididymal efferent duct absorptive cells: 23.8;Epididymal efferent duct ciliated cells: 31.1;Müller glia: 31.5;Oocytes: 142.8;Retinal bipolar cells: 25.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 1.2;memory CD4 T-cell: 1.4" "Lineage enriched" "Detected in single" 14 "T-cells: 1.4" "Low cancer specificity" "Detected in many" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027515, HPA054349" Enhanced Approved Nucleoplasm NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 15: Non-specific - Transcription" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 7 Nucleoplasm "HPA027515: , HPA054349: " "unprognostic (3.27e-2)" "unprognostic (7.17e-2)" "unprognostic (2.47e-1)" "unprognostic (1.16e-1)" "unprognostic (2.44e-1)" "unprognostic (8.94e-2)" "unprognostic (5.35e-2)" "unprognostic (3.98e-1)" "unprognostic (1.62e-2)" "potential prognostic favorable (9.82e-4)" "unprognostic (4.58e-2)" "potential prognostic favorable (6.31e-5)" "unprognostic (3.38e-3)" "unprognostic (2.26e-1)" "unprognostic (1.61e-1)" "unprognostic (2.12e-3)" "unprognostic (3.79e-3)" "unprognostic (9.99e-3)" "unprognostic (3.96e-1)" "unprognostic (1.87e-1)" "unprognostic (4.26e-1)" "unprognostic (2.91e-2)" "unprognostic (1.50e-1)" "unprognostic (1.11e-1)" "unprognostic (1.46e-1)" "unprognostic (1.25e-1)" "unprognostic (6.48e-2)" "unprognostic (1.52e-1)" "unprognostic (3.35e-1)" CIB1 "CIB, KIP, SIP2-28" ENSG00000185043 "Calcium and integrin binding 1" Q99828 15 90229975-90234047 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Angiogenesis, Apoptosis, Cell adhesion, Cell cycle, Cell division, Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 615.3;Fallopian tube ciliated cells: 911.2;Late spermatids: 2494.8;Respiratory ciliated cells: 963.3;Salivary duct cells: 645.2" "Cell type enhanced" "Detected in all" "ependymal cell: 74.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012991, HPA042413, HPA048825, HPA074310" Approved Supported "Nucleoplasm,Nuclear bodies,Plasma membrane" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 8: Immune cells - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 45 "Nucleoplasm, Plasma membrane" "Nuclear bodies" "CAB012991: , HPA042413: , HPA048825: , HPA074310: " "unprognostic (3.21e-2)" "unprognostic (2.44e-1)" "unprognostic (6.97e-2)" "unprognostic (1.05e-1)" "unprognostic (4.15e-2)" "unprognostic (1.22e-2)" "unprognostic (1.20e-2)" "unprognostic (5.28e-1)" "unprognostic (1.30e-1)" "unprognostic (1.47e-3)" "potential prognostic unfavorable (8.40e-5)" "unprognostic (3.32e-3)" "unprognostic (1.10e-1)" "unprognostic (9.42e-3)" "potential prognostic unfavorable (5.34e-4)" "unprognostic (1.46e-2)" "potential prognostic unfavorable (8.69e-5)" "unprognostic (1.07e-1)" "unprognostic (2.25e-2)" "unprognostic (4.28e-2)" "unprognostic (6.80e-2)" "potential prognostic unfavorable (5.07e-4)" "unprognostic (1.72e-1)" "unprognostic (1.08e-1)" "unprognostic (1.42e-2)" "unprognostic (5.60e-2)" "unprognostic (1.30e-1)" "unprognostic (2.82e-1)" "unprognostic (2.19e-1)" "unprognostic (2.54e-1)" "unprognostic (3.36e-1)" CIB2 "DFNB48, KIP2, USH1J" ENSG00000136425 "Calcium and integrin binding family member 2" O75838 15 78104606-78131535 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Cancer-related genes, Deafness, Disease variant, Non-syndromic deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 46.8;lymphoid tissue: 44.7" "Cell type enriched" "Detected in many" 5 "Late spermatids: 501.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 48 "plasmacytoid DC: 18.7" "Lineage enriched" "Detected in single" 48 "dendritic cells: 18.7" "Cancer enhanced" "Detected in all" "testis cancer: 45.5" "Skin - Inner root sheath cells, Skin - Outer root sheath cells, Stomach - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036697 Approved Uncertain "Nucleoplasm,Primary cilium transition zone,Centrosome,Cytosol" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 11: Neuronal - Sensory perception" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 32 Nucleoplasm "Primary cilium transition zone, Centrosome, Cytosol" "HPA036697: " "unprognostic (2.25e-2)" "unprognostic (6.22e-3)" "unprognostic (1.88e-1)" "unprognostic (1.85e-2)" "unprognostic (9.73e-2)" "unprognostic (9.00e-2)" "unprognostic (1.86e-1)" "unprognostic (2.85e-1)" "unprognostic (9.20e-2)" "unprognostic (7.70e-2)" "unprognostic (5.68e-3)" "unprognostic (1.32e-1)" "unprognostic (1.69e-1)" "unprognostic (6.87e-3)" "unprognostic (1.29e-3)" "unprognostic (1.24e-3)" "unprognostic (2.87e-1)" "unprognostic (1.14e-1)" "unprognostic (6.60e-2)" "unprognostic (2.91e-2)" "unprognostic (4.53e-2)" "unprognostic (1.54e-1)" "unprognostic (6.54e-3)" "unprognostic (4.52e-2)" "unprognostic (3.02e-1)" "unprognostic (1.47e-1)" "unprognostic (4.36e-2)" "unprognostic (3.68e-2)" "unprognostic (4.07e-2)" "unprognostic (1.30e-1)" "unprognostic (1.38e-2)" CIB3 KIP3 ENSG00000141977 "Calcium and integrin binding family member 3" Q96Q77 19 16161368-16173525 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "bone marrow: 1.2" "Cell type enriched" "Detected in some" 4 "Late spermatids: 15.4" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 9 "Breast Invasive Carcinoma (TCGA): 1.2" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "eosinophil: 2.3" "Lineage enriched" "Detected in single" 10 "granulocytes: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA043553, HPA043995" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 49: HMC-1 - Innate immune response" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 50 "Plasma membrane, Cytosol" "HPA043553: , HPA043995: " "unprognostic (2.41e-1)" "unprognostic (8.86e-2)" CIB4 ENSG00000157884 "Calcium and integrin binding family member 4" A0PJX0 2 26581205-26641366 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "testis: 16.6" "Group enriched" "Detected in some" 6 "Adrenal cortex cells: 81.5;Early spermatids: 142.6;Late primary spermatocytes: 197.8" "Cell type enhanced" "Detected in many" "lower rhombic lip: 7.7" "Group enriched" "Detected in some" 8 "Kidney Renal Clear Cell Carcinoma (TCGA): 2.5;Thyroid Carcinoma (TCGA): 1.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pituitary gland - Gonadotropes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA036130, HPA036131" Uncertain NA NA "Cluster 67: Testis - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 6 "HPA036130: , HPA036131: " "unprognostic (2.14e-3)" "unprognostic (9.57e-3)" "unprognostic (6.79e-3)" CIBAR1 "BARMR1, FAM92A, FAM92A1, FLJ38979" ENSG00000188343 "CBY1 interacting BAR domain containing 1" A1XBS5 8 93698561-93731527 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Differentiation, Spermatogenesis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 102.1" "Group enriched" "Detected in many" 4 "Early spermatids: 1493.3;Late primary spermatocytes: 999.5;Late spermatids: 952.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 144.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 3.3" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034760, HPA058942" Enhanced Supported Mitochondria NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 67: Testis - Mixed function" "Cluster 17: Choroid plexus - Cilium" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 5 Mitochondria "HPA034760: , HPA058942: " "unprognostic (3.01e-2)" "unprognostic (2.87e-2)" "potential prognostic unfavorable (9.84e-4)" "unprognostic (8.70e-3)" "unprognostic (5.05e-2)" "unprognostic (5.70e-1)" "potential prognostic favorable (6.57e-4)" "unprognostic (1.92e-2)" "unprognostic (1.75e-2)" "potential prognostic favorable (5.21e-5)" "unprognostic (1.08e-1)" "unprognostic (2.08e-1)" "unprognostic (2.01e-1)" "unprognostic (2.39e-1)" "unprognostic (3.84e-2)" "unprognostic (8.94e-2)" "unprognostic (6.55e-2)" "unprognostic (2.75e-1)" "unprognostic (7.92e-2)" "unprognostic (8.61e-3)" "unprognostic (1.18e-2)" "unprognostic (5.56e-2)" "unprognostic (7.24e-2)" "unprognostic (7.66e-3)" "unprognostic (2.08e-2)" "unprognostic (6.24e-3)" "unprognostic (5.18e-1)" "unprognostic (5.53e-2)" "unprognostic (5.02e-2)" CIBAR2 "FAM92B, FLJ44299" ENSG00000153789 "CBY1 interacting BAR domain containing 2" Q6ZTR7 16 85098358-85112472 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 33.4;fallopian tube: 80.4" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 193.1;Ependymal cells: 84.9;Epididymal efferent duct ciliated cells: 147.3;Fallopian tube ciliated cells: 442.3;Plasma cells: 54.1;Respiratory ciliated cells: 619.7" "Cell type enriched" "Detected in some" 8 "ependymal cell: 97.0" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 15.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Adrenal gland - Adrenal medulla cells, Breast - Plasma cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - Plasma cells, Spleen - Plasma cells" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA041022 Enhanced NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 107: Ciliated cells - Cilia assembly & function" 1 "HPA041022: " "unprognostic (1.54e-3)" "unprognostic (1.09e-2)" "unprognostic (2.41e-2)" "unprognostic (1.35e-1)" "unprognostic (2.44e-1)" "unprognostic (2.80e-1)" "unprognostic (6.88e-2)" "unprognostic (4.97e-1)" "unprognostic (5.57e-3)" CIC KIAA0306 ENSG00000079432 "Capicua transcriptional repressor" Q96RK0 19 42268537-42295797 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026388, HPA044341, HPA064725" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 42 Nucleoplasm Vesicles "CAB026388: , HPA044341: , HPA064725: " "unprognostic (3.68e-2)" "unprognostic (3.27e-2)" "unprognostic (7.88e-2)" "unprognostic (2.20e-1)" "unprognostic (1.04e-1)" "unprognostic (6.28e-2)" "unprognostic (3.85e-1)" "unprognostic (2.26e-1)" "potential prognostic favorable (6.53e-4)" "unprognostic (2.71e-1)" "unprognostic (1.38e-1)" "unprognostic (8.93e-2)" "unprognostic (4.56e-1)" "unprognostic (7.32e-3)" "unprognostic (1.53e-2)" "unprognostic (1.66e-2)" "unprognostic (8.93e-2)" "unprognostic (2.23e-1)" "unprognostic (1.65e-1)" "unprognostic (7.41e-3)" "unprognostic (1.30e-1)" "unprognostic (9.73e-3)" "unprognostic (9.16e-2)" "unprognostic (3.66e-1)" "unprognostic (5.82e-2)" "unprognostic (1.85e-2)" "unprognostic (3.64e-1)" "unprognostic (8.10e-2)" "unprognostic (7.65e-2)" "unprognostic (1.79e-2)" "unprognostic (2.11e-1)" CIDEA CIDE-A ENSG00000176194 "Cell death inducing DFFA like effector a" O60543 18 12254361-12277595 "Disease related genes, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "adipose tissue: 207.5;breast: 138.9" "Cell type enriched" "Detected in some" 16 "Breast lactating cells: 3480.9" "Cell type enriched" "Detected in some" 4 "deep-layer corticothalamic and 6b: 13.0" "Cancer enhanced" "Detected in some" "Breast Invasive Carcinoma (TCGA): 4.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Minor Salivary Gland - Adipocytes (Minor salivary gland), Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "spinal cord: 33.6" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 53: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 4: Breast lactating luminal cells - Lactation" 1 "unprognostic (1.04e-3)" "unprognostic (2.64e-2)" "unprognostic (5.69e-3)" "unprognostic (1.47e-1)" "unprognostic (4.11e-2)" "unprognostic (4.11e-2)" CIDEB ENSG00000136305 "Cell death inducing DFFA like effector b" Q9UHD4 14 24305187-24311430 "Predicted intracellular proteins" "Apoptosis, Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 175.5;liver: 448.3" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 1.7;Enterocytes: 3.9;Ependymal cells: 4.7;Hepatocytes: 3.1;Innate lymphoid cells: 2.2;Microglia: 3.5;NK-cells: 1.7;Papillary tip epithelial cells: 1.8" "Cell type enhanced" "Detected in some" "ependymal cell: 6.6;leukocyte: 7.6" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 41.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Leukemia: 10.7;liver cancer: 11.1;Myeloma: 10.9" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA001272, HPA059646" Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 25: Non-specific - Transcription" "Cluster 18: Liver cancer - Metabolism" "Cluster 102: Non-specific - Mixed function" 62 "Golgi apparatus, Vesicles" "HPA001272: , HPA059646: " "unprognostic (1.87e-2)" "unprognostic (3.54e-1)" "unprognostic (1.45e-1)" "unprognostic (5.93e-2)" "unprognostic (4.94e-2)" "unprognostic (1.20e-1)" "potential prognostic unfavorable (4.65e-4)" "unprognostic (6.68e-2)" "unprognostic (2.73e-2)" "unprognostic (5.51e-2)" "unprognostic (2.75e-2)" "potential prognostic favorable (4.59e-5)" "unprognostic (1.26e-2)" "potential prognostic favorable (6.45e-4)" "unprognostic (1.53e-2)" "unprognostic (1.03e-3)" "unprognostic (1.04e-3)" "unprognostic (2.21e-3)" "unprognostic (1.92e-1)" "unprognostic (1.12e-2)" "unprognostic (6.54e-2)" "unprognostic (4.71e-1)" "unprognostic (2.07e-1)" "unprognostic (1.05e-2)" "unprognostic (2.59e-1)" "unprognostic (5.06e-2)" "unprognostic (3.13e-1)" "unprognostic (4.57e-2)" "unprognostic (1.09e-1)" "unprognostic (2.58e-1)" "unprognostic (5.13e-2)" CIDEC "CIDE-3, FLJ20871, Fsp27" ENSG00000187288 "Cell death inducing DFFA like effector c" Q96AQ7 3 9866711-9880255 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Lipid transport, Transcription, Transcription regulation, Transport" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "adipose tissue: 704.3;breast: 500.3" "Group enriched" "Detected in some" 8 "Adipocytes: 196.9;Enterocytes: 321.6" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 12.0;Pancreatic Adenocarcinoma (TCGA): 11.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "colorectal cancer: 2.2;Gastric cancer: 7.0;liver cancer: 4.9;pancreatic cancer: 3.0" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Minor Salivary Gland - Adipocytes (Minor salivary gland), Prostate - Smooth muscle cells, Skin - Adipocytes (Skin)" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA018837, HPA020553" Uncertain NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 89: Adipocytes - Lipid metabolism" 6 "HPA018837: , HPA020553: " "unprognostic (8.76e-2)" "unprognostic (1.15e-2)" "unprognostic (2.02e-3)" "unprognostic (1.20e-1)" "unprognostic (1.18e-1)" "potential prognostic unfavorable (2.16e-4)" "unprognostic (1.91e-2)" "unprognostic (1.91e-3)" "unprognostic (1.03e-1)" "potential prognostic unfavorable (6.29e-6)" "unprognostic (3.45e-1)" "unprognostic (5.72e-3)" "unprognostic (1.06e-1)" "unprognostic (2.54e-1)" "unprognostic (1.87e-2)" "unprognostic (2.15e-3)" CIITA "C2TA, MHC2TA, NLRA" ENSG00000179583 "Class II major histocompatibility complex transactivator" P33076 16 10866222-10943021 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Acyltransferase, Kinase, Transferase" "Cancer-related genes, Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 50.4" "Cell type enhanced" "Detected in many" "B-cells: 169.4;Cardiomyocytes: 82.5;cDC: 521.5;Hematopoietic stem cells: 70.4;Macrophages: 199.0;Microglia: 213.7;monocytes: 81.1;pDCs: 192.0;Thymocytes: 72.8" "Cell type enriched" "Detected in many" 7 "central nervous system macrophage: 287.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 25.7;eosinophil: 15.5;intermediate monocyte: 20.5;memory B-cell: 35.6;myeloid DC: 41.2;naive B-cell: 51.1;non-classical monocyte: 23.5;plasmacytoid DC: 37.7" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 21.0;lymphoma: 41.6" "Adipose visceral - T-cells, Heart muscle - T-cells, Prostate - T-cells, Spleen - B-cells (Spleen), Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB016084, HPA054757" Enhanced Supported Nucleoplasm NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 82: Dendritic cells - Antigen presentation" 13 Nucleoplasm "CAB016084: , HPA054757: " "unprognostic (6.66e-3)" "unprognostic (1.55e-2)" "unprognostic (4.42e-3)" "unprognostic (8.61e-3)" "unprognostic (1.72e-1)" "unprognostic (7.97e-2)" "unprognostic (1.53e-1)" "unprognostic (1.87e-2)" "unprognostic (4.39e-3)" "unprognostic (2.00e-1)" "unprognostic (9.79e-2)" "unprognostic (9.02e-2)" "unprognostic (1.87e-2)" "unprognostic (3.09e-2)" "unprognostic (2.51e-2)" "unprognostic (4.24e-3)" "unprognostic (1.28e-1)" "unprognostic (6.04e-2)" "unprognostic (1.70e-1)" "unprognostic (5.61e-2)" "unprognostic (6.38e-3)" "unprognostic (1.75e-2)" "unprognostic (3.12e-1)" "unprognostic (3.19e-2)" "unprognostic (6.38e-3)" "unprognostic (6.46e-2)" "unprognostic (9.82e-3)" "unprognostic (9.17e-2)" "unprognostic (5.52e-3)" "unprognostic (2.30e-1)" "unprognostic (8.16e-3)" CILK1 "ICK, KIAA0936, LCK2, MGC46090, MRK" ENSG00000112144 "Ciliogenesis associated kinase 1" Q9UPZ9 6 53001279-53061824 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 117.2" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 137.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001113 Approved Approved "Golgi apparatus,Vesicles,Primary cilium,Primary cilium tip" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 18: Adrenal cortex cells - Steroidogensis" 15 "Golgi apparatus, Vesicles" "Primary cilium, Primary cilium tip" "HPA001113: " "unprognostic (1.95e-1)" "unprognostic (3.25e-3)" "unprognostic (3.67e-1)" "unprognostic (1.08e-1)" "unprognostic (2.90e-1)" "unprognostic (2.04e-1)" "unprognostic (7.99e-3)" "unprognostic (8.84e-2)" "unprognostic (2.46e-2)" "validated prognostic favorable (2.15e-5)" "validated prognostic favorable (1.58e-7)" "unprognostic (5.25e-2)" "unprognostic (3.09e-1)" "unprognostic (8.34e-2)" "unprognostic (1.14e-1)" "unprognostic (1.73e-3)" "unprognostic (3.58e-3)" "unprognostic (9.98e-2)" "potential prognostic unfavorable (8.86e-4)" "unprognostic (2.36e-2)" "unprognostic (1.17e-3)" "unprognostic (9.07e-2)" "unprognostic (2.04e-2)" "unprognostic (2.27e-2)" "unprognostic (1.66e-2)" "unprognostic (2.49e-1)" "unprognostic (2.30e-1)" "unprognostic (6.78e-2)" "unprognostic (4.77e-2)" CILP HsT18872 ENSG00000138615 "Cartilage intermediate layer protein" O75339 15 65194760-65211473 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 45.1;Fibro-adipogenic progenitors: 63.4;Fibroblasts: 163.9;Hepatic stellate cells: 58.1;Leydig cells: 363.4;Peritubular myoid cells: 82.6;Thymic myoid cells: 330.4" "Low cell type specificity" "Detected in single" "Cancer enriched" "Detected in many" 4 "Breast Invasive Carcinoma (TCGA): 46.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "ovarian cancer: 2.8;Uterine cancer: 3.7" "Breast - Fibroblasts, Colon - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblasts_2, Minor Salivary Gland - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblasts_2" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA003195 Uncertain "Secreted to extracellular matrix" "No annotated function" NA NA 5500000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 15: Kidney cancer - Membrane components" "Cluster 108: Fibroblasts - ECM organization" "HPA003195: " "unprognostic (2.60e-1)" "unprognostic (1.26e-2)" "unprognostic (1.46e-1)" "unprognostic (1.68e-2)" "unprognostic (9.15e-3)" "unprognostic (1.01e-1)" "unprognostic (2.97e-2)" "unprognostic (1.37e-1)" "unprognostic (1.13e-1)" "unprognostic (5.60e-2)" "unprognostic (1.89e-2)" "unprognostic (4.30e-1)" "unprognostic (6.23e-2)" "unprognostic (1.30e-2)" "unprognostic (1.52e-1)" "unprognostic (1.57e-1)" "unprognostic (2.58e-1)" "unprognostic (6.38e-2)" "unprognostic (1.03e-2)" "unprognostic (2.84e-2)" "unprognostic (2.30e-2)" "unprognostic (2.08e-1)" "potential prognostic unfavorable (1.86e-5)" "unprognostic (3.77e-2)" CILP2 MGC45771 ENSG00000160161 "Cartilage intermediate layer protein 2" Q8IUL8 19 19538248-19546659 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "ovary: 2.3;testis: 5.2" "Group enriched" "Detected in some" 6 "Early spermatids: 21.5;Late primary spermatocytes: 51.8;Late spermatids: 29.0" "Cell type enhanced" "Detected in single" "CGE interneuron: 2.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "medulla oblongata: 3.5;spinal cord: 9.6" HPA041847 Uncertain "Secreted to extracellular matrix" "No annotated function" NA NA 12000000 "Cluster 75: Ovary - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 4: Non-specific - Transcription" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 15 "HPA041847: " "unprognostic (1.25e-1)" "unprognostic (1.10e-1)" "unprognostic (1.16e-1)" "unprognostic (4.48e-2)" "unprognostic (1.25e-1)" "unprognostic (2.01e-1)" "unprognostic (1.16e-2)" "unprognostic (3.71e-2)" "unprognostic (5.34e-2)" "unprognostic (1.05e-1)" "potential prognostic unfavorable (1.97e-5)" "unprognostic (1.18e-2)" "unprognostic (4.72e-2)" "unprognostic (2.47e-2)" "unprognostic (1.25e-1)" "unprognostic (1.43e-1)" "unprognostic (1.81e-2)" "unprognostic (7.26e-2)" "unprognostic (2.60e-3)" "unprognostic (1.18e-2)" CINP MGC849 ENSG00000100865 "Cyclin dependent kinase 2 interacting protein" Q9BW66 14 102341102-102362916 "Essential proteins, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, DNA replication, Ribosome biogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal suprabasal cells: 121.8;Late primary spermatocytes: 192.3;Late spermatids: 173.7;Oocytes: 133.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 70: Non-specific - Protein processing" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 85: Squamous epithelial cells - Keratinization" 44 "unprognostic (2.60e-2)" "unprognostic (2.91e-1)" "unprognostic (8.96e-3)" "unprognostic (1.87e-2)" "unprognostic (1.08e-1)" "unprognostic (1.73e-1)" "unprognostic (2.20e-1)" "unprognostic (3.44e-2)" "potential prognostic unfavorable (2.51e-4)" "potential prognostic unfavorable (3.44e-4)" "unprognostic (5.18e-2)" "unprognostic (1.48e-1)" "unprognostic (3.44e-2)" "unprognostic (3.96e-3)" "unprognostic (1.13e-1)" "unprognostic (3.99e-3)" "unprognostic (2.11e-2)" "unprognostic (2.36e-1)" "unprognostic (2.95e-1)" "unprognostic (2.41e-1)" "unprognostic (9.63e-2)" "unprognostic (7.31e-3)" "unprognostic (9.63e-2)" "unprognostic (1.33e-1)" "unprognostic (7.45e-2)" "unprognostic (1.16e-2)" "unprognostic (3.80e-3)" "unprognostic (6.61e-2)" "unprognostic (1.42e-1)" "unprognostic (2.35e-1)" "unprognostic (4.94e-2)" CIP2A KIAA1524 ENSG00000163507 "Cellular inhibitor of PP2A" Q8TCG1 3 108549864-108589644 "Predicted intracellular proteins, Predicted membrane proteins" "DNA damage" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 48.6;Erythrocyte progenitors: 68.7;Late primary spermatocytes: 110.3;Megakaryocyte progenitors: 53.7;Monocyte progenitors: 119.1;Neutrophil progenitors: 87.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA039570 Approved Approved "Plasma membrane,Centrosome,Basal body,Cytosol" NA Yes "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 31: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 27: Non-specific - Cell proliferation" 19 Cytosol "Plasma membrane, Centrosome, Basal body" "HPA039570: " "unprognostic (1.27e-1)" "unprognostic (1.07e-1)" "unprognostic (8.12e-2)" "unprognostic (1.43e-2)" "unprognostic (9.53e-3)" "unprognostic (1.93e-1)" "unprognostic (1.37e-2)" "unprognostic (1.08e-1)" "unprognostic (2.77e-2)" "unprognostic (8.07e-2)" "potential prognostic unfavorable (6.14e-5)" "unprognostic (1.75e-3)" "unprognostic (8.03e-3)" "unprognostic (2.20e-1)" "unprognostic (1.37e-1)" "unprognostic (1.85e-3)" "validated prognostic unfavorable (7.37e-4)" "validated prognostic unfavorable (2.50e-4)" "unprognostic (6.58e-2)" "unprognostic (1.15e-1)" "unprognostic (8.22e-2)" "unprognostic (1.38e-2)" "unprognostic (1.38e-1)" "unprognostic (1.02e-3)" CIPC KIAA1737 ENSG00000198894 "CLOCK interacting pacemaker" Q9C0C6 14 77098126-77117287 "Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 123.7" "Cell type enhanced" "Detected in some" "Fallopian tube ciliated cells: 4.7;Late spermatids: 3.1;Respiratory ciliated cells: 2.7;Respiratory ionocytes: 2.5;Salivary ionocytes: 2.9" "Cell type enhanced" "Detected in some" "Bergmann glia: 4.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000644 Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 32: Basophils - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 107: Ciliated cells - Cilia assembly & function" 7 "Nucleoplasm, Cytosol" Nucleoli "HPA000644: " "unprognostic (3.94e-2)" "unprognostic (1.68e-1)" "unprognostic (1.69e-1)" "unprognostic (6.15e-2)" "unprognostic (2.84e-1)" "unprognostic (1.13e-1)" "unprognostic (3.17e-1)" "unprognostic (3.72e-1)" "unprognostic (2.18e-1)" "potential prognostic favorable (2.03e-7)" "unprognostic (1.16e-3)" "unprognostic (2.34e-2)" "unprognostic (1.36e-1)" "unprognostic (1.25e-2)" "unprognostic (8.42e-2)" "unprognostic (1.44e-1)" "unprognostic (8.30e-2)" "unprognostic (1.41e-1)" "unprognostic (2.61e-1)" "unprognostic (1.68e-1)" "unprognostic (1.76e-1)" "unprognostic (1.85e-1)" "unprognostic (1.45e-1)" "unprognostic (1.83e-1)" "unprognostic (4.42e-2)" "unprognostic (2.00e-1)" "unprognostic (2.58e-1)" "unprognostic (1.95e-1)" "unprognostic (3.43e-2)" CIR1 CIR ENSG00000138433 "Corepressor interacting with RBPJ, CIR1" Q86X95 2 174348022-174395712 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 560.4;Neutrophils: 583.9;Oocytes: 580.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 188.0" "Lineage enriched" "Detected in all" 4 "granulocytes: 188.0" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015784, HPA061442" Approved Supported "Nuclear speckles" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 14 "Nuclear speckles" "HPA015784: , HPA061442: " "unprognostic (2.37e-2)" "unprognostic (1.88e-1)" "unprognostic (1.49e-1)" "unprognostic (2.69e-1)" "unprognostic (1.14e-1)" "unprognostic (4.86e-2)" "unprognostic (3.91e-1)" "unprognostic (5.98e-2)" "unprognostic (1.11e-1)" "unprognostic (3.88e-2)" "unprognostic (5.71e-3)" "unprognostic (6.11e-3)" "unprognostic (3.83e-2)" "potential prognostic unfavorable (1.34e-4)" "unprognostic (4.35e-2)" "unprognostic (2.60e-1)" "unprognostic (1.80e-1)" "unprognostic (6.08e-2)" "unprognostic (1.06e-1)" "unprognostic (6.05e-2)" "unprognostic (7.15e-2)" "unprognostic (6.12e-2)" "unprognostic (1.11e-3)" "unprognostic (8.44e-2)" "unprognostic (2.26e-2)" "unprognostic (1.63e-2)" "unprognostic (4.43e-2)" "unprognostic (3.37e-1)" "unprognostic (4.07e-2)" "unprognostic (1.52e-1)" "unprognostic (8.67e-2)" CIRBP CIRP ENSG00000099622 "Cold inducible RNA binding protein" Q14011 19 1259384-1274880 "Plasma proteins, Predicted intracellular proteins" "Stress response" "Activator, Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060537 Supported Nucleoplasm NA NA 95000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 54: Non-specific - Ribosome" "Cluster 55: Non-specific - Transcription" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 37 Nucleoplasm "HPA060537: " "unprognostic (7.75e-3)" "potential prognostic favorable (7.99e-4)" "unprognostic (1.95e-1)" "unprognostic (1.03e-1)" "unprognostic (1.07e-1)" "unprognostic (2.33e-1)" "unprognostic (3.01e-1)" "unprognostic (4.84e-2)" "unprognostic (1.04e-1)" "unprognostic (6.58e-2)" "validated prognostic favorable (2.77e-9)" "validated prognostic favorable (1.25e-4)" "potential prognostic favorable (1.69e-6)" "unprognostic (1.27e-3)" "unprognostic (5.92e-2)" "unprognostic (4.02e-3)" "unprognostic (2.93e-1)" "unprognostic (1.24e-1)" "unprognostic (2.19e-2)" "unprognostic (3.53e-1)" "unprognostic (4.27e-1)" "unprognostic (1.56e-3)" "unprognostic (2.09e-1)" "unprognostic (1.16e-1)" "unprognostic (1.36e-1)" "unprognostic (5.70e-2)" "unprognostic (7.39e-2)" "unprognostic (4.59e-2)" "unprognostic (2.24e-2)" "unprognostic (1.76e-1)" "potential prognostic favorable (1.08e-5)" CIROP LMLN2 ENSG00000283654 "Ciliated left-right organizer metallopeptidase" A0A1B0GTW7 14 23099062-23104989 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant, Heterotaxy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "No human protein/transcript evidence" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Epicardial cells: 2.3;Oligodendrocytes: 1.3;Platelets: 2.8;Retinal amacrine cells: 3.5" "Cell type enhanced" "Detected in single" "oligodendrocyte: 1.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" NA NA "Cluster 6: Non-specific - Immune response" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" "unprognostic (4.04e-2)" CISD1 "C10orf70, MDS029, mitoNEET, ZCD1" ENSG00000122873 "CDGSH iron sulfur domain 1" Q9NZ45 10 58269162-58289586 "Enzymes, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 77.4" "Cell type enhanced" "Detected in many" "Enterocytes: 501.3;Gastric progenitor cells: 346.1;Late primary spermatocytes: 399.8;Late spermatids: 479.0;Parietal cells: 388.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074383 Supported Supported Mitochondria NA NA 13000 "Cluster 33: Non-specific - ATP binding" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" 8 Mitochondria "HPA074383: " "unprognostic (6.50e-2)" "unprognostic (3.16e-3)" "unprognostic (4.09e-2)" "unprognostic (7.36e-2)" "unprognostic (1.18e-1)" "unprognostic (6.24e-2)" "unprognostic (2.74e-3)" "potential prognostic favorable (9.05e-8)" "unprognostic (2.00e-2)" "unprognostic (2.28e-1)" "potential prognostic favorable (7.13e-5)" "unprognostic (8.53e-2)" "unprognostic (6.66e-3)" "unprognostic (4.35e-2)" "unprognostic (1.39e-3)" "potential prognostic unfavorable (8.85e-4)" "unprognostic (5.84e-2)" "unprognostic (7.85e-3)" "potential prognostic unfavorable (8.01e-4)" "unprognostic (3.53e-2)" "unprognostic (9.68e-2)" "unprognostic (4.60e-2)" "unprognostic (1.37e-1)" "unprognostic (5.94e-3)" "unprognostic (3.22e-2)" "unprognostic (1.10e-3)" "unprognostic (4.52e-2)" "unprognostic (4.17e-2)" "unprognostic (1.57e-1)" "unprognostic (2.23e-2)" "unprognostic (4.02e-1)" CISD2 "ERIS, Miner1, NAF-1, WFS2, ZCD2" ENSG00000145354 "CDGSH iron sulfur domain 2" Q8N5K1 4 102868974-102892807 "Disease related genes, Human disease related genes, Predicted membrane proteins" Autophagy "Deafness, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Kupffer cells: 183.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015914 Approved Supported "Endoplasmic reticulum" NA NA 6300 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 76: Non-specific - Metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 59: Leukemia - T-cell receptor" "Cluster 67: Plasma cells - Plasma cell differentiation" 85 "Endoplasmic reticulum" "HPA015914: " "unprognostic (3.18e-1)" "unprognostic (3.45e-2)" "unprognostic (2.47e-1)" "unprognostic (5.44e-3)" "unprognostic (2.23e-1)" "unprognostic (1.06e-1)" "unprognostic (1.49e-3)" "unprognostic (1.24e-1)" "unprognostic (5.61e-2)" "unprognostic (2.40e-2)" "potential prognostic favorable (8.00e-7)" "unprognostic (5.62e-2)" "unprognostic (2.83e-1)" "unprognostic (2.46e-1)" "unprognostic (8.02e-2)" "unprognostic (3.01e-2)" "unprognostic (4.46e-2)" "unprognostic (2.33e-2)" "unprognostic (1.91e-1)" "unprognostic (1.25e-1)" "unprognostic (8.63e-2)" "unprognostic (2.79e-1)" "unprognostic (5.12e-2)" "unprognostic (7.20e-2)" "unprognostic (9.38e-3)" "unprognostic (2.39e-1)" "unprognostic (6.41e-2)" "unprognostic (1.88e-2)" "unprognostic (1.88e-1)" "unprognostic (8.22e-2)" "unprognostic (1.34e-1)" CISD3 "Miner2, MiNT" ENSG00000277972 "CDGSH iron sulfur domain 3" P0C7P0 17 38730341-38735605 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Enterocytes: 51.5;Foveolar cells: 40.0;Gastric chief cells: 57.9;Hepatocytes: 64.9;Mucous neck cells: 35.8;Parietal cells: 116.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053436, HPA054400" Approved NA NA "Cluster 70: Non-specific - Protein processing" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Breast cancer - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 1 "HPA053436: , HPA054400: " "unprognostic (4.30e-1)" "unprognostic (1.52e-1)" "unprognostic (5.68e-2)" "potential prognostic favorable (1.04e-4)" "unprognostic (4.46e-2)" "unprognostic (9.48e-3)" "unprognostic (7.28e-2)" "unprognostic (2.25e-2)" "unprognostic (4.26e-3)" "unprognostic (1.85e-2)" "unprognostic (3.80e-1)" "unprognostic (4.71e-3)" "validated prognostic unfavorable (4.97e-4)" "validated prognostic unfavorable (4.97e-6)" "unprognostic (2.04e-2)" "unprognostic (6.87e-2)" "unprognostic (5.69e-2)" "unprognostic (3.71e-3)" "unprognostic (9.01e-3)" "potential prognostic unfavorable (3.14e-4)" "unprognostic (5.30e-2)" "unprognostic (2.88e-3)" "unprognostic (2.32e-1)" "unprognostic (2.66e-2)" "unprognostic (6.86e-2)" "unprognostic (1.15e-1)" CISH "CIS, CIS-1, G18, SOCS" ENSG00000114737 "Cytokine inducible SH2 containing protein" Q9NSE2 3 50606489-50611774 "Predicted intracellular proteins" "Growth regulation, Ubl conjugation pathway" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 59.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 32.7;Alveolar cells type 2: 81.9;Breast lactating cells: 79.3;Epididymal efferent duct absorptive cells: 46.1;Fallopian tube ciliated cells: 31.9;Transitional alveolar cells: 41.3" "Cell type enriched" "Detected in some" 13 "leukocyte: 46.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 6 "breast cancer: 18.6;Leukemia: 48.5;lymphoma: 13.5" "Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034039, HPA040812" Approved Approved "Microtubules,Cytokinetic bridge" Yes No "Cluster 11: T-cells - Unknown function" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 8: Immune cells - Immune response" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 81: Alveolar cells - Lung function" 14 Microtubules "Cytokinetic bridge" "CAB034039: , HPA040812: " "unprognostic (9.68e-3)" "unprognostic (4.32e-3)" "unprognostic (2.35e-1)" "unprognostic (3.56e-2)" "unprognostic (2.45e-2)" "unprognostic (5.85e-2)" "unprognostic (5.93e-2)" "unprognostic (6.08e-2)" "unprognostic (1.45e-1)" "unprognostic (3.29e-1)" "potential prognostic favorable (2.27e-7)" "unprognostic (3.58e-2)" "potential prognostic favorable (3.75e-4)" "unprognostic (6.33e-3)" "unprognostic (8.45e-2)" "potential prognostic favorable (3.92e-4)" "unprognostic (1.88e-1)" "unprognostic (6.36e-3)" "unprognostic (1.13e-2)" "unprognostic (2.60e-1)" "unprognostic (6.57e-2)" "unprognostic (1.02e-2)" "unprognostic (5.41e-2)" "unprognostic (7.79e-2)" "unprognostic (5.56e-2)" "unprognostic (9.27e-2)" "unprognostic (1.68e-1)" "unprognostic (9.61e-2)" "unprognostic (2.61e-1)" "unprognostic (1.70e-1)" "unprognostic (6.41e-2)" CIT "CITK, CRIK, KIAA0949, STK21" ENSG00000122966 "Citron rho-interacting serine/threonine kinase" O14578 12 119685791-119877320 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Mitosis, Neurogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 13.4;lymphoid tissue: 6.3" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 122.0;Brain inhibitory neurons: 190.2;Cone photoreceptor cells: 105.6;Distal convoluted tubule cells: 120.1;Ependymal cells: 132.8;Erythrocyte progenitors: 140.6;Megakaryocyte progenitors: 114.7;Monocyte progenitors: 203.0;Neutrophil progenitors: 102.8;Oligodendrocyte progenitor cells: 123.9;Other brain neurons: 103.7;Transitional alveolar cells: 109.5" "Cell type enhanced" "Detected in all" "thalamic excitatory: 651.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Colon - Enteric glia cells, Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019082, HPA048812, HPA075506" Uncertain Approved Cytosol NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 27: Non-specific - Cell proliferation" 18 Cytosol "HPA019082: , HPA048812: , HPA075506: " "unprognostic (5.25e-2)" "unprognostic (9.25e-2)" "unprognostic (2.46e-1)" "unprognostic (1.57e-1)" "unprognostic (2.84e-1)" "unprognostic (4.86e-2)" "unprognostic (3.71e-1)" "unprognostic (5.99e-2)" "unprognostic (2.61e-1)" "unprognostic (2.95e-3)" "potential prognostic favorable (7.82e-4)" "unprognostic (1.60e-1)" "unprognostic (8.38e-2)" "potential prognostic unfavorable (1.29e-5)" "validated prognostic unfavorable (8.77e-4)" "validated prognostic unfavorable (4.30e-4)" "unprognostic (1.00e-1)" "unprognostic (5.92e-2)" "unprognostic (2.36e-1)" "unprognostic (2.45e-1)" "potential prognostic unfavorable (1.36e-4)" "unprognostic (2.98e-3)" "unprognostic (8.72e-2)" "unprognostic (2.01e-1)" "unprognostic (4.03e-1)" "unprognostic (2.74e-2)" "unprognostic (8.17e-2)" "unprognostic (5.47e-2)" CITED1 MSG1 ENSG00000125931 "Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1" Q99966 X 72301638-72307187 "Predicted intracellular proteins" "Apoptosis, Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "epididymis: 1389.4" "Cell type enriched" "Detected in some" 11 "Epididymal principal cells: 1935.6" "Cell type enhanced" "Detected in many" "mammillary body: 10.3" "Cancer enriched" "Detected in many" 6 "Thyroid Carcinoma (TCGA): 489.0" "Region enhanced" "Detected in all" "hypothalamus: 117.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Neuroblastoma: 9.0;skin cancer: 32.2" "Breast - Breast glandular cells, Prostate - Prostate glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049051 Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 69: Skin cancer - ECM organization" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 8 Nucleoplasm Cytosol "HPA049051: " "unprognostic (4.79e-2)" "unprognostic (2.04e-1)" "unprognostic (8.86e-2)" "unprognostic (1.23e-2)" "unprognostic (4.63e-1)" "unprognostic (1.21e-2)" "unprognostic (3.23e-2)" "unprognostic (1.22e-1)" "unprognostic (9.23e-2)" "unprognostic (6.85e-2)" "unprognostic (3.80e-1)" "unprognostic (2.15e-1)" "unprognostic (1.13e-2)" "potential prognostic favorable (7.45e-4)" "unprognostic (1.25e-1)" "unprognostic (1.07e-1)" "unprognostic (2.13e-2)" "unprognostic (3.29e-1)" "unprognostic (2.33e-1)" "unprognostic (2.20e-2)" "unprognostic (8.85e-3)" "potential prognostic favorable (4.02e-4)" "unprognostic (1.57e-1)" CITED2 MRG1 ENSG00000164442 "Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2" Q99967 6 139371807-139374648 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Stress response, Transcription, Transcription regulation" "Activator, Developmental protein, Repressor" "Atrial septal defect, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 874.1;Extravillous trophoblasts: 1005.7;Hofbauer cells: 641.3;Migrating cytotrophoblasts: 414.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 27.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016157, HPA067368, HPA069092, CAB069879" Supported Supported "Nucleoplasm,Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 20: Non-specific - Transcription regulation" 14 Nucleoplasm "Golgi apparatus, Vesicles, Cytosol" "CAB016157: , CAB069879: , HPA067368: , HPA069092: " "unprognostic (3.00e-1)" "unprognostic (2.35e-1)" "unprognostic (2.10e-1)" "unprognostic (1.31e-3)" "unprognostic (3.51e-1)" "unprognostic (3.28e-3)" "unprognostic (1.75e-1)" "unprognostic (1.51e-1)" "unprognostic (8.59e-2)" "unprognostic (3.59e-1)" "potential prognostic favorable (1.08e-6)" "unprognostic (6.91e-2)" "unprognostic (1.33e-1)" "unprognostic (2.19e-2)" "unprognostic (1.31e-1)" "unprognostic (2.23e-2)" "unprognostic (2.63e-1)" "unprognostic (4.04e-3)" "unprognostic (4.11e-3)" "unprognostic (9.87e-3)" "unprognostic (2.79e-1)" "unprognostic (6.07e-2)" "potential prognostic unfavorable (1.51e-4)" "unprognostic (1.56e-2)" "unprognostic (3.74e-3)" "unprognostic (1.59e-2)" "unprognostic (6.75e-3)" "unprognostic (4.01e-3)" "unprognostic (1.27e-1)" "unprognostic (6.10e-2)" "unprognostic (7.04e-2)" CITED4 ENSG00000179862 "Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 4" Q96RK1 1 40861054-40862363 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast secretory cells: 350.3;Cholangiocytes: 321.5;Endometrial ciliated cells: 345.7;Endometrial glandular cells: 194.0;Endometrial luminal cells: 181.4;Epididymal efferent duct absorptive cells: 264.9;Fallopian secretory cells: 170.0;Pancreatic duct cells: 461.9;Retinal pigment epithelial cells: 238.7" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Uterine Corpus Endometrial Carcinoma (TCGA): 177.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 7 "Adrenocortical cancer: 233.9" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA056434 Approved Approved Vesicles NA NA "Cluster 24: Non-specific - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 1 Vesicles "HPA056434: " "unprognostic (5.82e-2)" "unprognostic (3.68e-3)" "unprognostic (8.94e-3)" "unprognostic (2.46e-1)" "unprognostic (1.72e-1)" "unprognostic (3.45e-3)" "unprognostic (1.91e-3)" "unprognostic (4.41e-2)" "unprognostic (3.76e-2)" "unprognostic (2.34e-2)" "unprognostic (3.83e-2)" "unprognostic (2.55e-1)" "unprognostic (1.60e-3)" "unprognostic (1.34e-3)" "unprognostic (3.42e-3)" "unprognostic (6.24e-2)" "unprognostic (1.11e-1)" "unprognostic (5.15e-2)" "unprognostic (1.00e-1)" "unprognostic (3.33e-2)" "unprognostic (2.25e-1)" "unprognostic (3.49e-3)" "unprognostic (9.56e-2)" "unprognostic (7.87e-2)" "unprognostic (1.37e-1)" "potential prognostic favorable (4.21e-4)" "unprognostic (4.14e-1)" "unprognostic (1.16e-1)" "unprognostic (2.61e-1)" "unprognostic (3.03e-1)" "unprognostic (4.57e-3)" CIZ1 "LSFR1, ZNF356" ENSG00000148337 "CDKN1A interacting zinc finger protein 1" Q9ULV3 9 128161251-128204383 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Dystonia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 115.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020380, HPA020387" Uncertain Enhanced Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 24: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 17 Nucleoplasm "HPA020380: , HPA020387: " "unprognostic (7.15e-2)" "unprognostic (2.15e-1)" "unprognostic (3.62e-1)" "unprognostic (3.18e-1)" "unprognostic (1.21e-1)" "potential prognostic unfavorable (5.48e-5)" "unprognostic (6.84e-3)" "unprognostic (2.45e-1)" "unprognostic (1.05e-2)" "unprognostic (5.19e-2)" "unprognostic (3.38e-3)" "unprognostic (1.09e-2)" "unprognostic (3.57e-1)" "potential prognostic unfavorable (3.98e-4)" "unprognostic (6.48e-3)" "unprognostic (8.24e-2)" "unprognostic (1.14e-2)" "unprognostic (2.63e-1)" "unprognostic (8.84e-3)" "unprognostic (1.21e-2)" "unprognostic (2.29e-1)" "unprognostic (1.37e-1)" "unprognostic (2.70e-2)" "unprognostic (9.45e-3)" "unprognostic (2.94e-2)" "unprognostic (1.05e-1)" "unprognostic (3.96e-1)" "unprognostic (2.43e-1)" "unprognostic (1.15e-1)" "unprognostic (2.86e-1)" "unprognostic (8.42e-2)" CKAP2 "FLJ10749, LB1, se20-10, TMAP" ENSG00000136108 "Cytoskeleton associated protein 2" Q8WWK9 13 52455429-52476628 "Predicted intracellular proteins" "Apoptosis, Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 63.9" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 184.0;Erythrocyte progenitors: 127.6;Granulosa cells: 91.6;Late primary spermatocytes: 113.8;Megakaryocyte progenitors: 103.8;Monocyte progenitors: 141.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA008410, HPA027821" Enhanced Supported "Microtubules,Mitotic spindle,Primary cilium,Centrosome,Basal body" Yes Yes "Cluster 32: Basophils - Transcription" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 2: Neurons - Nucleosome" "Cluster 19: Non-specific - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 28 "Microtubules, Mitotic spindle, Primary cilium" "Centrosome, Basal body" "HPA008410: , HPA027821: " "unprognostic (3.42e-2)" "unprognostic (2.16e-1)" "unprognostic (3.69e-2)" "unprognostic (5.54e-3)" "unprognostic (1.00e-1)" "unprognostic (1.64e-1)" "unprognostic (4.08e-2)" "unprognostic (6.77e-3)" "unprognostic (5.09e-2)" "potential prognostic unfavorable (1.16e-4)" "unprognostic (1.17e-3)" "unprognostic (5.95e-2)" "potential prognostic unfavorable (5.66e-4)" "validated prognostic unfavorable (6.25e-5)" "validated prognostic unfavorable (5.22e-5)" "unprognostic (4.13e-3)" "unprognostic (1.50e-2)" "unprognostic (3.54e-1)" "unprognostic (9.80e-2)" "potential prognostic unfavorable (2.02e-4)" "unprognostic (2.01e-1)" "unprognostic (5.02e-2)" "unprognostic (1.78e-3)" "unprognostic (8.11e-3)" "unprognostic (2.78e-2)" "unprognostic (1.90e-2)" "unprognostic (2.75e-2)" "unprognostic (7.66e-2)" "unprognostic (9.37e-2)" "unprognostic (9.17e-2)" "unprognostic (1.09e-1)" CKAP2L "FLJ40629, radmis" ENSG00000169607 "Cytoskeleton associated protein 2 like" Q8IYA6 2 112736349-112764664 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 12.4;lymphoid tissue: 11.2" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 43.9;Early primary spermatocytes: 42.7;Early spermatids: 27.4;Endometrial luminal cells: 26.1;Erythrocyte progenitors: 55.5;Esophageal basal cells: 31.2;Late primary spermatocytes: 24.5;Megakaryocyte progenitors: 130.0;Megakaryocytes: 61.8;Monocyte progenitors: 66.2;Neutrophil progenitors: 32.0;Undifferentiated spermatogonia: 43.5" "Cell type enhanced" "Detected in single" "hippocampal dentate gyrus: 1.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA039407, HPA040057, HPA070737" Uncertain Supported "Microtubules,Mitotic spindle,Primary cilium,Cytosol" Yes Yes "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 9: Non-specific - Receptor signaling" "Cluster 72: Neuronal - Signal transduction" "Cluster 27: Non-specific - Cell proliferation" 5 Microtubules "Mitotic spindle, Primary cilium, Cytosol" "HPA039407: , HPA040057: , HPA070737: " "potential prognostic unfavorable (9.98e-4)" "unprognostic (3.10e-1)" "unprognostic (2.47e-1)" "unprognostic (9.76e-2)" "unprognostic (1.15e-2)" "unprognostic (1.47e-1)" "unprognostic (2.98e-1)" "unprognostic (4.53e-3)" "unprognostic (2.09e-1)" "potential prognostic unfavorable (8.82e-4)" "validated prognostic unfavorable (9.06e-5)" "validated prognostic unfavorable (2.29e-6)" "validated prognostic unfavorable (3.57e-5)" "validated prognostic unfavorable (4.81e-5)" "unprognostic (1.97e-1)" "unprognostic (1.68e-1)" "unprognostic (1.09e-1)" "unprognostic (2.31e-1)" "validated prognostic unfavorable (2.18e-5)" "validated prognostic unfavorable (1.08e-4)" "unprognostic (1.53e-1)" "unprognostic (3.79e-1)" "unprognostic (6.45e-3)" "unprognostic (8.83e-2)" "unprognostic (8.82e-2)" "unprognostic (1.23e-3)" CKAP4 "CLIMP-63, ERGIC-63, P63" ENSG00000136026 "Cytoskeleton associated protein 4" Q07065 12 106237881-106304279 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 300.5;Endometrial glandular cells: 227.4;Esophageal apical cells: 319.2;Neutrophil progenitors: 551.3;Neutrophils: 656.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 107.4" "Lineage enriched" "Detected in many" 6 "granulocytes: 107.4" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000278, HPA000792, HPA001753" Enhanced Supported "Nuclear speckles,Endoplasmic reticulum,Mitochondria" NA NA 120000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 113 "Endoplasmic reticulum" "Nuclear speckles, Mitochondria" "HPA000278: , HPA000792: , HPA001753: " "unprognostic (1.71e-1)" "unprognostic (2.32e-2)" "unprognostic (8.87e-2)" "unprognostic (4.59e-3)" "unprognostic (3.00e-1)" "unprognostic (1.94e-2)" "unprognostic (7.32e-2)" "unprognostic (9.92e-3)" "unprognostic (3.59e-2)" "unprognostic (2.28e-1)" "validated prognostic unfavorable (3.91e-9)" "validated prognostic unfavorable (5.67e-5)" "unprognostic (7.67e-2)" "validated prognostic unfavorable (4.70e-4)" "validated prognostic unfavorable (1.39e-4)" "potential prognostic unfavorable (1.82e-4)" "unprognostic (5.23e-3)" "unprognostic (1.61e-1)" "unprognostic (2.92e-1)" "unprognostic (1.43e-1)" "unprognostic (1.42e-2)" "unprognostic (3.65e-1)" "unprognostic (3.20e-1)" "unprognostic (1.51e-1)" "unprognostic (5.97e-3)" "unprognostic (4.17e-2)" "unprognostic (1.48e-2)" "unprognostic (2.40e-3)" "unprognostic (2.21e-1)" "unprognostic (1.04e-3)" "unprognostic (4.04e-2)" CKAP5 "ch-TOG, KIAA0097, TOG, TOGp" ENSG00000175216 "Cytoskeleton associated protein 5" Q14008 11 46743048-46846308 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039377, HPA040375" Supported Approved "Nucleoli,Nucleoli rim,Plasma membrane,Mitotic spindle,Primary cilium,Centrosome,Basal body" Yes Yes 160000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 38 "Centrosome, Basal body" "Nucleoli, Nucleoli rim, Plasma membrane, Mitotic spindle, Primary cilium" "HPA039377: , HPA040375: " "unprognostic (6.22e-2)" "unprognostic (6.92e-3)" "unprognostic (2.42e-1)" "unprognostic (2.84e-3)" "unprognostic (2.16e-1)" "unprognostic (1.25e-1)" "unprognostic (3.83e-1)" "unprognostic (1.38e-1)" "unprognostic (1.78e-1)" "potential prognostic unfavorable (2.79e-7)" "unprognostic (4.39e-3)" "unprognostic (1.58e-1)" "unprognostic (1.19e-1)" "potential prognostic unfavorable (6.48e-7)" "unprognostic (5.66e-3)" "unprognostic (1.94e-2)" "potential prognostic unfavorable (6.42e-5)" "unprognostic (2.33e-1)" "unprognostic (2.45e-1)" "unprognostic (2.62e-1)" "unprognostic (2.27e-1)" "unprognostic (1.38e-2)" "unprognostic (1.38e-2)" "unprognostic (7.63e-2)" "unprognostic (8.18e-3)" "unprognostic (2.22e-2)" "unprognostic (2.87e-1)" "unprognostic (3.99e-1)" "unprognostic (6.51e-2)" "unprognostic (6.30e-2)" "unprognostic (7.41e-2)" CKB CKBB ENSG00000166165 "Creatine kinase B" P12277 14 103519667-103522833 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1487.2;intestine: 1025.7" "Cell type enhanced" "Detected in many" "Colonocytes: 6345.6;Cone photoreceptor cells: 2246.1;Fallopian tube ciliated cells: 1301.0;Müller glia: 2585.4;Parietal cells: 5522.9;Retinal bipolar cells: 1423.8;Retinal horizontal cells: 2350.0;Rod photoreceptor cells: 1636.6;Smooth muscle cells: 1464.7" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 1264.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 10 "non-classical monocyte: 292.6" "Lineage enriched" "Detected in many" 18 "monocytes: 292.6" "Cancer enhanced" "Detected in all" "prostate cancer: 769.0" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001254, CAB047313" Enhanced Supported Cytosol No No 22000000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 78: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 60: Prostate cancer - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 32 Cytosol "CAB047313: , HPA001254: " "unprognostic (5.35e-2)" "unprognostic (4.14e-2)" "unprognostic (3.77e-1)" "unprognostic (4.27e-3)" "unprognostic (3.61e-2)" "potential prognostic favorable (7.02e-5)" "unprognostic (9.28e-2)" "unprognostic (1.14e-1)" "unprognostic (2.36e-1)" "unprognostic (1.21e-1)" "unprognostic (1.83e-3)" "unprognostic (2.72e-1)" "potential prognostic favorable (1.36e-6)" "unprognostic (8.86e-2)" "unprognostic (2.05e-1)" "unprognostic (1.13e-1)" "unprognostic (1.03e-1)" "unprognostic (7.67e-2)" "unprognostic (2.06e-2)" "unprognostic (1.52e-1)" "unprognostic (3.62e-1)" "unprognostic (2.03e-2)" "unprognostic (3.82e-2)" "unprognostic (3.69e-2)" "unprognostic (2.11e-3)" "unprognostic (1.95e-2)" "unprognostic (1.79e-1)" "unprognostic (4.36e-2)" "unprognostic (1.20e-1)" "unprognostic (1.45e-3)" "unprognostic (1.25e-1)" CKLF "C32, CKLF1, CKLF3, CKLF4, HSPC224, UCK-1" ENSG00000217555 "Chemokine like factor" Q9UBR5 16 66552563-66566251 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "cDC: 196.5;Early primary spermatocytes: 186.0;Gastric progenitor cells: 439.6;Hofbauer cells: 205.7;Late primary spermatocytes: 361.3;Mast cells: 258.9;Megakaryocytes: 210.2;Neutrophils: 399.4" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 163.9;leukocyte: 171.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1394.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA062779 Approved "Vesicles,Mid piece,Principal piece" "Secreted to blood" Cytokine NA NA 31700 "Cluster 21: Neutrophils - Unknown function" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 39: Astrocytes - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 1 Vesicles "Mid piece, Principal piece" "HPA062779: " "unprognostic (6.97e-2)" "unprognostic (1.34e-1)" "unprognostic (2.01e-1)" "unprognostic (2.62e-2)" "unprognostic (5.77e-2)" "unprognostic (9.20e-2)" "unprognostic (6.55e-2)" "unprognostic (5.30e-2)" "unprognostic (1.82e-1)" "unprognostic (8.85e-2)" "unprognostic (2.05e-2)" "unprognostic (3.51e-1)" "unprognostic (2.23e-2)" "validated prognostic unfavorable (1.06e-9)" "validated prognostic unfavorable (4.29e-4)" "unprognostic (1.89e-1)" "unprognostic (1.91e-3)" "unprognostic (5.49e-2)" "unprognostic (1.42e-3)" "unprognostic (1.14e-1)" "unprognostic (1.44e-2)" "unprognostic (1.62e-3)" "unprognostic (6.55e-2)" "unprognostic (8.38e-2)" "unprognostic (1.58e-1)" "unprognostic (3.83e-1)" "unprognostic (1.02e-1)" "unprognostic (2.69e-1)" "unprognostic (2.55e-1)" "potential prognostic favorable (2.36e-4)" "unprognostic (7.66e-2)" CKLF-CMTM1 ENSG00000254788 "CKLF-CMTM1 readthrough" 16 66552587-66579135 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "testis: 5.8" "Cell type enhanced" "Detected in some" "Early spermatids: 3.2;Epicardial cells: 2.3;Hepatic stellate cells: 6.5;Late primary spermatocytes: 3.7;Late spermatids: 14.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" HPA017136 Approved NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 6: Non-specific - Immune response" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" "HPA017136: " "unprognostic (2.45e-2)" "unprognostic (7.79e-2)" "unprognostic (6.54e-2)" "unprognostic (3.58e-2)" "unprognostic (5.17e-3)" "unprognostic (2.28e-1)" "potential prognostic favorable (5.37e-4)" "unprognostic (5.46e-3)" "unprognostic (1.22e-1)" "unprognostic (1.42e-1)" "unprognostic (1.12e-1)" "unprognostic (5.14e-2)" "unprognostic (4.59e-2)" "potential prognostic unfavorable (2.88e-5)" "unprognostic (2.33e-2)" "unprognostic (5.65e-2)" "unprognostic (4.14e-2)" "potential prognostic unfavorable (2.98e-5)" "unprognostic (3.85e-2)" "unprognostic (1.32e-1)" "unprognostic (1.63e-1)" "unprognostic (1.71e-1)" "unprognostic (1.63e-1)" "unprognostic (2.95e-2)" "unprognostic (1.96e-1)" CKM CKMM ENSG00000104879 "Creatine kinase, M-type" P06732 19 45306413-45322875 "Candidate cardiovascular disease genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "skeletal muscle: 68908.9;tongue: 24326.4" "Group enriched" "Detected in many" 6 "Myonuclei: 773.6;Thymic myoid cells: 1948.3" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Head and Neck Squamous Cell Carcinoma (TCGA): 103.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Sarcoma: 5.6" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Stomach - Parietal cells" "Region enriched" "Detected in single" 15 "olfactory bulb: 1.5" "Not detected" "Not detected" HPA047859 Enhanced NA NA 87000000 "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 37: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 23 "HPA047859: " "unprognostic (1.43e-1)" "unprognostic (1.94e-1)" "unprognostic (4.28e-3)" "unprognostic (1.44e-1)" "unprognostic (1.29e-3)" "unprognostic (8.16e-2)" "unprognostic (3.46e-1)" CKMT1A CKMT1 ENSG00000223572 "Creatine kinase, mitochondrial 1A" P12532 15 43692886-43699222 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 73.9;esophagus: 82.6;intestine: 70.3" "Cell type enhanced" "Detected in many" "Colonocytes: 122.8;Cytotrophoblasts: 93.7;Enteric stem cells: 83.3;Enteric transient amplifying cells: 113.2;Enterocytes: 71.2;Esophageal apical cells: 56.6;Esophageal basal cells: 74.0;Esophageal suprabasal cells: 99.9;Foveolar cells: 40.8;Goblet cells: 45.3;Migrating cytotrophoblasts: 45.3;Suprabasal keratinocytes: 42.9;Syncytiotrophoblasts: 109.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Minor Salivary Gland - Minor salivary gland basal cells" HPA043491 Uncertain "Intracellular and membrane" Enzyme NA NA 1100000 "Cluster 64: Non-specific - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 97: Non-specific - Cellular respiration" 18 "HPA043491: " "unprognostic (5.60e-2)" "unprognostic (5.99e-3)" "unprognostic (2.81e-1)" "potential prognostic favorable (2.97e-4)" "unprognostic (6.22e-2)" "unprognostic (6.49e-3)" "unprognostic (2.47e-1)" "unprognostic (4.11e-3)" "unprognostic (1.41e-1)" "unprognostic (1.57e-1)" "unprognostic (1.68e-1)" "unprognostic (2.21e-2)" "potential prognostic favorable (1.01e-4)" "unprognostic (2.20e-1)" "potential prognostic unfavorable (8.42e-4)" "unprognostic (5.39e-2)" "unprognostic (2.59e-1)" "unprognostic (1.90e-2)" "unprognostic (1.91e-2)" "unprognostic (3.24e-2)" "unprognostic (6.42e-2)" "unprognostic (2.84e-1)" "unprognostic (6.87e-2)" "unprognostic (2.75e-2)" "unprognostic (2.91e-1)" "unprognostic (2.13e-2)" "unprognostic (1.06e-1)" "unprognostic (5.84e-2)" "unprognostic (4.84e-2)" "unprognostic (1.41e-1)" "unprognostic (9.23e-3)" CKMT1B "CKMT, CKMT1, UMTCK" ENSG00000237289 "Creatine kinase, mitochondrial 1B" P12532 15 43593054-43604901 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 112.1;esophagus: 73.3;intestine: 75.6" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 70.9;Colonocytes: 155.6;Cytotrophoblasts: 165.9;Enteric stem cells: 99.3;Enteric transient amplifying cells: 136.7;Enterocytes: 110.2;Esophageal apical cells: 56.4;Esophageal basal cells: 63.5;Esophageal suprabasal cells: 86.9;Goblet cells: 66.1;Migrating cytotrophoblasts: 61.6;Syncytiotrophoblasts: 154.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Minor Salivary Gland - Minor salivary gland basal cells" HPA043491 Uncertain "Intracellular and membrane" Enzyme NA NA 1100000 "Cluster 64: Non-specific - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 97: Non-specific - Cellular respiration" 15 "HPA043491: " "unprognostic (1.50e-1)" "unprognostic (1.30e-1)" "unprognostic (1.27e-3)" "potential prognostic favorable (6.90e-5)" "unprognostic (1.23e-1)" "unprognostic (2.20e-2)" "unprognostic (4.62e-2)" "unprognostic (1.01e-2)" "unprognostic (4.83e-1)" "unprognostic (8.73e-2)" "unprognostic (1.60e-1)" "unprognostic (7.41e-2)" "unprognostic (2.12e-3)" "unprognostic (9.25e-2)" "unprognostic (3.47e-2)" "unprognostic (1.57e-1)" "unprognostic (1.28e-2)" "unprognostic (2.51e-2)" "unprognostic (4.19e-2)" "unprognostic (6.88e-2)" "unprognostic (4.52e-1)" "unprognostic (7.22e-2)" "unprognostic (5.31e-3)" "unprognostic (4.06e-1)" "unprognostic (5.32e-2)" "unprognostic (7.58e-2)" "unprognostic (1.42e-1)" "unprognostic (2.92e-1)" "unprognostic (1.23e-1)" "potential prognostic unfavorable (4.45e-4)" CKMT2 SMTCK ENSG00000131730 "Creatine kinase, mitochondrial 2" P17540 5 81233320-81266398 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 28 "heart muscle: 1157.4;skeletal muscle: 1341.7;tongue: 2166.2" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 79.0;Cardiomyocytes: 254.4;Choroid plexus epithelial cells: 112.0;Myonuclei: 640.5;Thymic myoid cells: 163.2" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 117.5" "Cancer enriched" "Detected in many" 10 "Kidney Chromophobe (TCGA): 156.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "NK-cell: 1.1" "Lineage enriched" "Detected in single" 7 "NK-cells: 1.1" "Cancer enhanced" "Detected in many" "colorectal cancer: 7.1;thyroid cancer: 7.2" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Cardiomyocytes, Kidney - Intercalated cells, Pituitary gland - Gonadotropes, Prostate - Smooth muscle cells, Skin - Eccrine sweat gland cells, Stomach - Parietal cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA051880 Enhanced NA NA 1100000 "Cluster 41: Striated muscle - Muscle contraction" "Cluster 47: Endothelial cells - Vasculature" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 55: Myocytes - Oxidative muscle function" 31 "HPA051880: " "unprognostic (9.52e-2)" "unprognostic (2.35e-3)" "unprognostic (1.55e-2)" "unprognostic (7.84e-2)" "unprognostic (2.02e-2)" "potential prognostic unfavorable (2.88e-4)" "unprognostic (2.44e-3)" "unprognostic (1.57e-2)" "potential prognostic unfavorable (2.46e-6)" "unprognostic (5.41e-2)" "unprognostic (1.41e-1)" "unprognostic (1.19e-3)" "unprognostic (1.30e-1)" "unprognostic (4.23e-2)" "potential prognostic favorable (5.04e-4)" "unprognostic (3.93e-1)" "unprognostic (5.05e-2)" "unprognostic (9.99e-2)" "unprognostic (1.54e-1)" "unprognostic (1.13e-1)" "unprognostic (8.40e-2)" "unprognostic (3.69e-2)" "unprognostic (7.46e-3)" "unprognostic (2.39e-3)" "unprognostic (9.31e-2)" "unprognostic (1.15e-1)" "unprognostic (1.13e-1)" "unprognostic (1.22e-1)" CKS1B "CKS1, ckshs1" ENSG00000173207 "CDC28 protein kinase regulatory subunit 1B" P61024 1 154974653-154979251 "Cancer-related genes, Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 147.4;Enteric transient amplifying cells: 170.4;Extravillous trophoblasts: 525.8;Gastric progenitor cells: 434.5;Migrating cytotrophoblasts: 265.9;Oocytes: 331.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003424, HPA030762" Approved Approved Nucleoplasm,Vesicles,Mitochondria,Cytosol NA Yes "Cluster 13: Non-specific - Mitochondria" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 30: White matter - Myelination" "Cluster 45: Non-specific - Nuclear processes" "Cluster 27: Non-specific - Cell proliferation" 78 "Mitochondria, Cytosol" "Nucleoplasm, Vesicles" "HPA003424: , HPA030762: " "unprognostic (2.84e-3)" "unprognostic (4.85e-2)" "unprognostic (9.84e-3)" "unprognostic (2.74e-2)" "unprognostic (2.44e-1)" "unprognostic (3.31e-2)" "unprognostic (4.31e-1)" "unprognostic (3.40e-3)" "unprognostic (3.59e-2)" "unprognostic (1.88e-1)" "potential prognostic favorable (2.48e-4)" "unprognostic (7.86e-2)" "potential prognostic unfavorable (1.45e-6)" "potential prognostic unfavorable (3.42e-6)" "unprognostic (2.04e-3)" "potential prognostic unfavorable (1.45e-4)" "unprognostic (4.16e-3)" "unprognostic (2.79e-2)" "unprognostic (3.60e-2)" "unprognostic (1.20e-1)" "unprognostic (7.05e-2)" "potential prognostic unfavorable (5.65e-4)" "unprognostic (2.16e-1)" "unprognostic (2.66e-1)" "unprognostic (2.39e-1)" "unprognostic (3.88e-1)" "unprognostic (1.70e-1)" "unprognostic (1.10e-1)" "unprognostic (2.81e-1)" "unprognostic (8.02e-3)" "unprognostic (1.93e-2)" CKS2 ENSG00000123975 "CDC28 protein kinase regulatory subunit 2" P33552 9 89311195-89316703 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 167.0;testis: 175.8" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 609.6;Early primary spermatocytes: 577.8;Extravillous trophoblasts: 422.1;Gastric progenitor cells: 480.6;Granulosa cells: 440.4;Late primary spermatocytes: 1009.5;Migrating cytotrophoblasts: 346.0;Oocytes: 741.4;Undifferentiated spermatogonia: 337.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 188.4" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA003424, HPA030762" Approved Approved Nucleoplasm,Vesicles,Mitochondria,Cytosol NA Yes "Cluster 13: Non-specific - Mitochondria" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 20: Non-specific - Transcription regulation" 26 "Mitochondria, Cytosol" "Nucleoplasm, Vesicles" "HPA003424: , HPA030762: " "unprognostic (4.67e-3)" "unprognostic (8.75e-3)" "unprognostic (2.48e-2)" "unprognostic (2.46e-1)" "unprognostic (7.68e-2)" "unprognostic (1.04e-1)" "unprognostic (4.81e-3)" "unprognostic (3.93e-2)" "unprognostic (4.48e-2)" "unprognostic (1.97e-3)" "unprognostic (1.05e-3)" "potential prognostic unfavorable (7.50e-4)" "potential prognostic unfavorable (1.69e-9)" "validated prognostic unfavorable (3.86e-6)" "validated prognostic unfavorable (4.78e-7)" "potential prognostic unfavorable (9.45e-4)" "unprognostic (2.95e-2)" "unprognostic (8.45e-2)" "unprognostic (4.77e-2)" "unprognostic (8.03e-2)" "unprognostic (3.77e-2)" "potential prognostic unfavorable (8.99e-4)" "unprognostic (4.19e-3)" "unprognostic (2.65e-3)" "unprognostic (8.55e-2)" "unprognostic (9.99e-2)" "unprognostic (2.85e-2)" "unprognostic (1.41e-2)" "unprognostic (2.83e-1)" "unprognostic (2.13e-1)" "unprognostic (1.04e-1)" CLASP1 "KIAA0622, MAST1" ENSG00000074054 "Cytoplasmic linker associated protein 1" Q7Z460 2 121337776-121649476 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 937.4;Myonuclei: 1039.1;Neutrophils: 834.9;Rod photoreceptor cells: 790.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 6.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065219 Uncertain NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 1: Neurons - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 79: Photoreceptor cells - Phototransduction" 66 "HPA065219: " "unprognostic (2.22e-1)" "unprognostic (4.29e-2)" "unprognostic (1.22e-1)" "unprognostic (1.27e-1)" "unprognostic (1.57e-1)" "unprognostic (3.07e-1)" "unprognostic (8.30e-3)" "unprognostic (1.47e-2)" "unprognostic (3.85e-1)" "unprognostic (1.19e-1)" "potential prognostic favorable (6.88e-5)" "unprognostic (8.73e-3)" "unprognostic (3.94e-2)" "unprognostic (2.86e-2)" "unprognostic (9.44e-2)" "unprognostic (2.35e-1)" "unprognostic (2.90e-2)" "unprognostic (7.91e-2)" "potential prognostic favorable (1.62e-4)" "unprognostic (6.23e-2)" "unprognostic (1.63e-1)" "unprognostic (1.46e-1)" "potential prognostic unfavorable (9.52e-4)" "unprognostic (2.94e-1)" "unprognostic (1.63e-1)" "potential prognostic favorable (2.46e-4)" "unprognostic (3.18e-2)" "unprognostic (2.57e-1)" "unprognostic (3.66e-1)" "unprognostic (8.68e-2)" "unprognostic (1.13e-1)" CLASP2 KIAA0627 ENSG00000163539 "Cytoplasmic linker associated protein 2" O75122 3 33496245-33718356 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 105.5;retina: 117.3" "Cell type enhanced" "Detected in all" "Oligodendrocyte progenitor cells: 1118.1;Oligodendrocytes: 1707.4;Rod photoreceptor cells: 938.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pituitary gland - Lactotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067071 Supported "Golgi apparatus,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 56 "Golgi apparatus" Cytosol "HPA067071: " "unprognostic (9.50e-2)" "unprognostic (4.74e-1)" "unprognostic (1.69e-1)" "potential prognostic unfavorable (4.62e-4)" "unprognostic (1.33e-1)" "unprognostic (2.02e-1)" "unprognostic (5.62e-3)" "unprognostic (1.02e-3)" "unprognostic (6.84e-3)" "potential prognostic unfavorable (6.47e-4)" "potential prognostic favorable (5.78e-7)" "unprognostic (1.48e-3)" "unprognostic (2.57e-2)" "unprognostic (2.76e-2)" "unprognostic (1.48e-1)" "unprognostic (4.79e-2)" "unprognostic (9.17e-2)" "unprognostic (4.10e-2)" "unprognostic (1.34e-1)" "unprognostic (1.32e-1)" "unprognostic (1.64e-1)" "unprognostic (8.61e-2)" "unprognostic (7.35e-2)" "unprognostic (2.62e-2)" "unprognostic (4.89e-3)" "potential prognostic favorable (7.99e-5)" "unprognostic (2.43e-1)" "unprognostic (1.09e-1)" "unprognostic (2.22e-1)" "unprognostic (9.57e-3)" "unprognostic (6.91e-2)" CLASRP "CLASP, SFRS16, SWAP2" ENSG00000104859 "CLK4 associating serine/arginine rich protein" Q8N2M8 19 45039045-45070956 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA060469, HPA062455" Approved Supported Nucleoplasm NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 4: Non-specific - Transcription" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 18 Nucleoplasm "HPA060469: , HPA062455: " "unprognostic (1.10e-1)" "unprognostic (6.71e-2)" "unprognostic (5.44e-2)" "unprognostic (2.86e-2)" "unprognostic (3.25e-1)" "unprognostic (1.97e-1)" "unprognostic (2.69e-1)" "unprognostic (5.30e-3)" "unprognostic (2.38e-1)" "potential prognostic unfavorable (1.93e-4)" "unprognostic (3.48e-2)" "unprognostic (3.52e-3)" "unprognostic (4.38e-2)" "unprognostic (2.19e-1)" "unprognostic (8.92e-2)" "unprognostic (2.17e-2)" "unprognostic (8.92e-2)" "unprognostic (9.47e-2)" "unprognostic (2.14e-2)" "unprognostic (3.94e-2)" "unprognostic (3.17e-2)" "unprognostic (1.92e-2)" "unprognostic (2.01e-1)" "unprognostic (1.83e-1)" "unprognostic (2.07e-1)" "unprognostic (8.44e-2)" "unprognostic (9.88e-2)" "unprognostic (4.46e-2)" "unprognostic (1.72e-1)" "unprognostic (1.38e-1)" CLBA1 C14orf79 ENSG00000140104 "Clathrin binding box of aftiphilin containing 1" Q96F83 14 104985775-105010482 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 36.6;Endometrial ciliated cells: 52.0;Fallopian tube ciliated cells: 54.0;Late primary spermatocytes: 47.9;Respiratory ciliated cells: 44.4" "Cell type enhanced" "Detected in all" "ependymal cell: 31.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042052, HPA061117, HPA078556" Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 21: Testis - Mixed function" "Cluster 17: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" Vesicles "Nucleoplasm, Cytosol" "HPA042052: , HPA061117: , HPA078556: " "unprognostic (2.66e-2)" "unprognostic (6.97e-2)" "unprognostic (2.12e-1)" "unprognostic (1.23e-1)" "unprognostic (5.21e-2)" "unprognostic (1.14e-3)" "unprognostic (2.66e-1)" "unprognostic (3.78e-2)" "unprognostic (6.77e-2)" "unprognostic (3.65e-2)" "unprognostic (1.21e-2)" "unprognostic (6.57e-3)" "unprognostic (1.79e-1)" "unprognostic (9.32e-2)" "unprognostic (2.98e-1)" "unprognostic (1.88e-1)" "unprognostic (1.59e-1)" "unprognostic (8.26e-2)" "unprognostic (2.42e-1)" "unprognostic (2.37e-2)" "unprognostic (7.56e-2)" "unprognostic (2.70e-3)" "unprognostic (5.37e-3)" "unprognostic (9.84e-2)" "unprognostic (5.08e-2)" "unprognostic (6.49e-2)" "unprognostic (1.55e-1)" "unprognostic (1.77e-1)" "unprognostic (7.55e-2)" CLC "Gal-10, LGALS10, MGC149659" ENSG00000105205 "Charcot-Leyden crystal galectin" Q05315 19 39731255-39738029 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "bone marrow: 426.7" "Cell type enriched" "Detected in some" 5 "Neutrophil progenitors: 191.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rectum Adenocarcinoma (TCGA): 3.6" "Region enriched" "Detected in single" 4 "hypothalamus: 1.7" "Group enriched" "Detected in all" 312 "basophil: 28919.8;eosinophil: 21548.5" "Lineage enriched" "Detected in all" 2255 "granulocytes: 28919.8" "Cancer enriched" "Detected in single" 327 "Leukemia: 107.0" "Spleen - Neutrophils_1" "Not detected" "Not detected" HPA041751 Enhanced NA NA 490000 "Cluster 22: Eosinophils - Transcription" "Cluster 15: Bone marrow - Innate immune response" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 49: HMC-1 - Innate immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" "HPA041751: " "unprognostic (4.73e-1)" "unprognostic (2.38e-2)" "unprognostic (2.49e-1)" "unprognostic (1.64e-2)" "unprognostic (4.41e-2)" "unprognostic (1.14e-1)" "unprognostic (5.29e-3)" "unprognostic (7.95e-2)" "unprognostic (2.65e-1)" "unprognostic (4.31e-2)" "unprognostic (3.33e-3)" CLCA1 "CaCC, CLCRG1" ENSG00000016490 "Chloride channel accessory 1" A8K7I4 1 86468368-86500259 "Predicted secreted proteins, Transporters" "Calcium transport, Ion transport, Transport" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "intestine: 1318.0" "Cell type enriched" "Detected in some" 234 "Goblet cells: 6414.5" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "Colon Adenocarcinoma (TCGA): 159.5;Pancreatic Adenocarcinoma (TCGA): 41.6;Rectum Adenocarcinoma (TCGA): 65.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "ovarian cancer: 27.7" "Colon - Colon enterocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA052787, HPA059301" Enhanced "Secreted to digestive system" Transport NA NA 7600 "Cluster 77: Intestine - Digestion" "Cluster 66: Non-specific - Mitochondria" "Cluster 70: Intestinal goblet cells - Mucin production" "HPA052787: , HPA059301: " "unprognostic (1.04e-3)" "unprognostic (1.90e-2)" "unprognostic (3.21e-1)" "unprognostic (9.32e-2)" "unprognostic (1.79e-2)" "unprognostic (2.39e-1)" "unprognostic (1.86e-2)" "unprognostic (2.37e-1)" CLCA2 CLCRG2 ENSG00000137975 "Chloride channel accessory 2" Q9UQC9 1 86424171-86456553 "Predicted membrane proteins, Transporters" "Cell adhesion, Ion transport, Transport" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 43.0;esophagus: 110.4;skin 1: 83.8;vagina: 53.4" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 124.1;Esophageal apical cells: 411.2;Esophageal basal cells: 217.0;Esophageal suprabasal cells: 480.0;Ocular epithelial cells: 204.0;Prostatic hillock cells: 155.5;Respiratory basal cells: 100.8;Respiratory deuterosomal cells: 85.0;Respiratory secretory cells: 172.7;Suprabasal keratinocytes: 216.0" "Cell type enriched" "Detected in single" 4 "oligodendrocyte: 2.8" "Group enriched" "Detected in many" 6 "Bladder Urothelial Carcinoma (TCGA): 61.6;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 121.1;Head and Neck Squamous Cell Carcinoma (TCGA): 233.8;Lung Squamous Cell Carcinoma (TCGA): 108.2" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "breast cancer: 24.6;Esophageal cancer: 13.5;Gallbladder cancer: 13.2;head and neck cancer: 29.1" "Lung - Respiratory ciliated cells, Prostate - Urothelial cells, Skin - Mitotic cells (Skin), Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA047192 Enhanced Supported "Nucleoplasm,Plasma membrane,Cell Junctions" "Intracellular and membrane" Transport NA NA 54000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" "Plasma membrane, Cell Junctions" Nucleoplasm "HPA047192: " "unprognostic (1.31e-1)" "unprognostic (8.10e-3)" "unprognostic (5.03e-1)" "unprognostic (9.65e-2)" "unprognostic (1.13e-1)" "unprognostic (2.29e-1)" "unprognostic (1.20e-1)" "potential prognostic favorable (4.12e-4)" "unprognostic (2.65e-1)" "unprognostic (6.91e-2)" "unprognostic (8.69e-2)" "unprognostic (2.12e-1)" CLCA4 CaCC2 ENSG00000016602 "Chloride channel accessory 4" Q14CN2 1 86547078-86580754 "Predicted membrane proteins, Transporters" Transport "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 352.4;intestine: 241.9" "Cell type enriched" "Detected in some" 6 "Esophageal apical cells: 5466.2" "Group enriched" "Detected in some" 20 "committed oligodendrocyte precursor: 14.4;oligodendrocyte: 54.9" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 32.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Bladder cancer: 10.1" "Colon - Colon enterocytes, Prostate - Urothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA017045, HPA064770" Uncertain Approved "Nucleoplasm,Plasma membrane,Aggresome" "Intracellular and membrane" Transport NA NA 150000 "Cluster 11: Esophagus - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" "Plasma membrane" "Nucleoplasm, Aggresome" "HPA017045: , HPA064770: " "unprognostic (1.12e-2)" "unprognostic (9.64e-2)" "unprognostic (2.15e-3)" "unprognostic (1.67e-2)" "unprognostic (3.76e-1)" "unprognostic (2.02e-3)" "unprognostic (4.72e-1)" "unprognostic (1.02e-1)" "unprognostic (7.15e-2)" "unprognostic (5.02e-1)" "unprognostic (1.92e-1)" "unprognostic (1.33e-1)" "unprognostic (8.00e-2)" "unprognostic (6.36e-2)" CLCC1 MCLC ENSG00000121940 "Chloride channel CLIC like 1" Q96S66 1 108881885-108963527 "Disease related genes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 21.3;Epididymal principal cells: 19.1;Plasma cells: 19.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009087, HPA013210" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 78: Plasma cells - Antibody production & ER-stress response" 15 "Endoplasmic reticulum" "HPA009087: , HPA013210: " "unprognostic (2.37e-2)" "unprognostic (1.89e-1)" "unprognostic (2.63e-2)" "unprognostic (9.11e-3)" "unprognostic (6.48e-3)" "unprognostic (3.49e-3)" "unprognostic (3.83e-1)" "unprognostic (1.82e-1)" "unprognostic (9.52e-2)" "potential prognostic unfavorable (4.94e-5)" "potential prognostic favorable (1.23e-6)" "unprognostic (1.49e-2)" "unprognostic (1.21e-1)" "unprognostic (1.37e-2)" "unprognostic (5.88e-2)" "unprognostic (1.77e-1)" "unprognostic (2.78e-1)" "unprognostic (5.67e-2)" "unprognostic (5.13e-2)" "unprognostic (1.49e-1)" "unprognostic (7.48e-2)" "unprognostic (7.39e-2)" "unprognostic (4.86e-1)" "unprognostic (1.75e-1)" "potential prognostic favorable (1.41e-4)" "unprognostic (1.04e-2)" "unprognostic (3.61e-2)" "unprognostic (1.38e-1)" "unprognostic (9.28e-2)" "unprognostic (5.21e-3)" "unprognostic (1.72e-1)" CLCF1 "BSF-3, BSF3, CISS2, CLC, NNT-1, NNT1, NR6" ENSG00000175505 "Cardiotrophin like cytokine factor 1" Q9UBD9 11 67364168-67374177 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted secreted proteins" Cytokine "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast secretory cells: 36.0;Cholangiocytes: 35.5;Endometrial glandular cells: 76.9;Endometrial luminal cells: 57.9;Epididymal efferent duct absorptive cells: 56.9;Epididymal efferent duct ciliated cells: 54.1;Fallopian secretory cells: 67.6;Pancreatic duct cells: 36.9;Schwann cells: 37.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Spleen - B-cells (Spleen)" "Not detected" "Not detected" "Region enhanced" "Detected in some" "spinal cord: 3.9" HPA042444 Uncertain Approved "Nuclear bodies,Vesicles" "Secreted to blood" Cytokine NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 51: Secretory epithelial cells - Mixed function" 2 "Nuclear bodies, Vesicles" "HPA042444: " "unprognostic (3.17e-1)" "unprognostic (1.37e-1)" "unprognostic (2.48e-1)" "potential prognostic unfavorable (6.03e-4)" "unprognostic (4.97e-2)" "unprognostic (2.17e-1)" "unprognostic (1.26e-3)" "unprognostic (8.68e-3)" "unprognostic (5.67e-2)" "unprognostic (7.05e-2)" "unprognostic (1.53e-1)" "unprognostic (2.41e-1)" "unprognostic (2.35e-2)" "unprognostic (1.94e-3)" "unprognostic (1.10e-1)" "unprognostic (1.43e-2)" "unprognostic (2.57e-3)" "unprognostic (8.13e-3)" "unprognostic (3.10e-2)" "unprognostic (9.74e-3)" "unprognostic (2.09e-1)" "unprognostic (5.46e-3)" "potential prognostic unfavorable (2.05e-4)" "unprognostic (2.12e-1)" "unprognostic (5.01e-2)" "potential prognostic favorable (1.09e-4)" "unprognostic (1.03e-1)" "unprognostic (3.52e-2)" "unprognostic (1.62e-1)" "unprognostic (6.41e-2)" "unprognostic (9.09e-3)" CLCN1 "ClC-1, CLC1" ENSG00000188037 "Chloride voltage-gated channel 1" P35523 7 143316111-143352083 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "skeletal muscle: 60.4" "Group enriched" "Detected in some" 5 "Late spermatids: 203.0;Myonuclei: 280.1" "Cell type enhanced" "Detected in some" "pericyte: 2.0" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.4" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in single" 7 "Gallbladder cancer: 3.1" "Skeletal muscle - Skeletal myocytes, Stomach - Gastric mucous cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 35: Non-specific - DNA binding" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 7 "unprognostic (9.87e-3)" CLCN2 "ClC-2, CLC2, EJM6" ENSG00000114859 "Chloride voltage-gated channel 2" P51788 3 184346185-184361650 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 15.2" "Cell type enhanced" "Detected in many" "Astrocytes: 23.0;Colonocytes: 65.6;Enterocytes: 28.3;Retinal ganglion cells: 23.2;Retinal pigment epithelial cells: 85.3;Sertoli cells: 34.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009397, HPA014545, HPA024108" Approved Approved Cytosol NA NA "Cluster 21: Testis - Mixed function" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" Cytosol "CAB009397: , HPA014545: , HPA024108: " "unprognostic (2.43e-1)" "unprognostic (9.91e-2)" "unprognostic (3.38e-3)" "unprognostic (2.99e-1)" "unprognostic (3.71e-1)" "unprognostic (8.19e-2)" "unprognostic (9.94e-2)" "unprognostic (2.97e-3)" "unprognostic (2.25e-3)" "unprognostic (1.14e-1)" "potential prognostic favorable (4.90e-5)" "unprognostic (1.10e-1)" "unprognostic (3.12e-1)" "potential prognostic unfavorable (4.21e-4)" "unprognostic (3.13e-3)" "unprognostic (2.84e-2)" "unprognostic (1.39e-2)" "unprognostic (7.37e-3)" "potential prognostic favorable (2.39e-6)" "unprognostic (4.93e-1)" "unprognostic (5.71e-3)" "unprognostic (4.31e-3)" "unprognostic (3.09e-1)" "unprognostic (9.96e-2)" "unprognostic (1.03e-1)" "unprognostic (2.59e-1)" "unprognostic (5.61e-2)" "unprognostic (5.70e-2)" "unprognostic (1.44e-1)" "unprognostic (5.15e-2)" "unprognostic (1.73e-2)" CLCN3 "ClC-3, CLC3" ENSG00000109572 "Chloride voltage-gated channel 3" P51790 4 169612633-169723673 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Antiport, Ion transport, Transport" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 426.0;Platelets: 714.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044723 Approved Supported Vesicles NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 42: Retina - Visual perception" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 69: Urothelial cells - Basic cellular functions" 5 Vesicles "HPA044723: " "unprognostic (4.08e-2)" "unprognostic (1.91e-1)" "unprognostic (5.78e-2)" "unprognostic (7.96e-3)" "unprognostic (9.44e-3)" "unprognostic (4.30e-2)" "unprognostic (2.19e-1)" "unprognostic (9.32e-2)" "unprognostic (1.16e-1)" "unprognostic (6.23e-2)" "potential prognostic favorable (2.07e-7)" "unprognostic (1.55e-3)" "unprognostic (2.07e-1)" "unprognostic (9.64e-2)" "unprognostic (2.16e-1)" "unprognostic (8.39e-3)" "unprognostic (1.39e-1)" "unprognostic (1.19e-1)" "unprognostic (3.09e-1)" "unprognostic (5.28e-2)" "unprognostic (8.29e-2)" "unprognostic (3.17e-2)" "unprognostic (3.36e-1)" "unprognostic (6.49e-2)" "unprognostic (4.57e-2)" "unprognostic (5.93e-2)" "unprognostic (2.19e-1)" "unprognostic (9.70e-2)" "unprognostic (2.34e-1)" "unprognostic (6.68e-2)" "unprognostic (6.40e-2)" CLCN4 "ClC-4, CLC4" ENSG00000073464 "Chloride voltage-gated channel 4" P51793 X 10156975-10237660 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Transport" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.3;retina: 35.1;skeletal muscle: 41.9;tongue: 32.0" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 151.1;Epididymal principal cells: 124.7;Erythrocyte progenitors: 68.3;Oligodendrocytes: 86.2;Retinal amacrine cells: 63.4;Retinal bipolar cells: 91.6;Retinal pigment epithelial cells: 106.6;Rod photoreceptor cells: 63.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 1.7;memory B-cell: 1.0;naive B-cell: 2.6;neutrophil: 2.2" "Group enriched" "Detected in many" 6 "B-cells: 2.6;granulocytes: 2.2" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031313, HPA063637" Enhanced Approved Supported Vesicles NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 7 Vesicles "HPA031313: , HPA063637: " "unprognostic (1.12e-2)" "unprognostic (1.48e-1)" "unprognostic (4.59e-3)" "unprognostic (6.39e-2)" "unprognostic (1.82e-1)" "potential prognostic unfavorable (1.06e-4)" "unprognostic (2.51e-1)" "unprognostic (1.76e-1)" "unprognostic (9.51e-2)" "potential prognostic favorable (1.26e-5)" "unprognostic (4.41e-3)" "unprognostic (1.06e-1)" "unprognostic (2.50e-3)" "unprognostic (2.45e-2)" "unprognostic (3.34e-1)" "unprognostic (1.52e-1)" "unprognostic (3.83e-2)" "unprognostic (1.33e-1)" "unprognostic (3.97e-1)" "unprognostic (5.60e-3)" "unprognostic (4.55e-2)" "unprognostic (5.39e-2)" "unprognostic (1.86e-1)" "unprognostic (2.00e-1)" "unprognostic (1.18e-3)" "unprognostic (6.08e-2)" "unprognostic (1.25e-1)" "unprognostic (2.26e-1)" "unprognostic (1.55e-1)" "unprognostic (1.62e-1)" CLCN5 "ClC-5, CLC5, DENTS, hCIC-K2, hClC-K2, NPHL1, NPHL2, XLRH, XRN" ENSG00000171365 "Chloride voltage-gated channel 5" P51795 X 49922596-50099235 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "epididymis: 22.3;kidney: 43.1;liver: 15.8" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 453.3;Loop of henle epithelial cells: 447.2;Myosatellite cells: 714.4;Proximal tubule cells: 173.6;Renal connecting tubule cells: 218.0" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 169.2" "Cancer enhanced" "Detected in all" "Kidney Renal Papillary Cell Carcinoma (TCGA): 18.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.6;plasmacytoid DC: 2.8" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Kidney - Ascending Loop of Henle cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000401, HPA003213" Uncertain Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 9 "Golgi apparatus, Plasma membrane" Cytosol "HPA000401: , HPA003213: " "unprognostic (1.38e-2)" "unprognostic (2.92e-3)" "unprognostic (1.86e-2)" "unprognostic (1.42e-1)" "unprognostic (7.92e-2)" "unprognostic (1.95e-1)" "unprognostic (7.77e-2)" "unprognostic (8.92e-2)" "unprognostic (1.21e-1)" "unprognostic (1.19e-1)" "validated prognostic favorable (1.11e-10)" "validated prognostic favorable (3.80e-4)" "unprognostic (1.41e-2)" "unprognostic (2.08e-1)" "unprognostic (8.47e-2)" "unprognostic (1.45e-1)" "unprognostic (9.85e-2)" "unprognostic (1.57e-2)" "unprognostic (1.68e-2)" "unprognostic (1.30e-1)" "unprognostic (3.70e-1)" "unprognostic (2.40e-3)" "unprognostic (3.46e-1)" "unprognostic (6.24e-2)" "unprognostic (4.88e-2)" "unprognostic (5.24e-3)" "unprognostic (1.69e-2)" "unprognostic (9.88e-2)" "unprognostic (1.59e-1)" "unprognostic (6.58e-2)" "unprognostic (2.11e-1)" CLCN6 "CLC-6, KIAA0046" ENSG00000011021 "Chloride voltage-gated channel 6" P51797 1 11806096-11848079 "Disease related genes, Plasma proteins, Predicted membrane proteins" "Antiport, Ion transport, Transport" "Disease variant, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 133.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032097 Approved Uncertain "Plasma membrane,Cytosol" No No "Cluster 23: B-cells - Immunoglobulins" "Cluster 64: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" "Plasma membrane, Cytosol" "HPA032097: " "unprognostic (1.07e-2)" "unprognostic (1.68e-1)" "unprognostic (1.45e-1)" "unprognostic (5.58e-2)" "unprognostic (1.06e-1)" "unprognostic (5.70e-2)" "unprognostic (2.30e-1)" "unprognostic (3.36e-2)" "unprognostic (6.93e-2)" "unprognostic (1.67e-1)" "validated prognostic favorable (5.98e-5)" "validated prognostic favorable (3.86e-4)" "unprognostic (2.23e-3)" "potential prognostic unfavorable (3.11e-5)" "unprognostic (5.40e-2)" "unprognostic (1.26e-2)" "unprognostic (2.16e-1)" "unprognostic (2.52e-2)" "unprognostic (3.49e-1)" "unprognostic (3.12e-2)" "unprognostic (2.87e-1)" "unprognostic (1.11e-2)" "unprognostic (9.16e-3)" "unprognostic (2.21e-1)" "unprognostic (2.87e-1)" "potential prognostic favorable (3.60e-5)" "unprognostic (1.48e-1)" "unprognostic (1.56e-1)" "unprognostic (2.56e-1)" "unprognostic (4.51e-2)" "unprognostic (3.29e-1)" CLCN7 "CLC-7, CLC7, OPTA2, PPP1R63" ENSG00000103249 "Chloride voltage-gated channel 7" P51798 16 1444934-1475077 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Transport" "Disease variant, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Melanocytes: 112.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 150.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043019, HPA043586" Supported NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 61: Schwann cells & Melanocytes - Mixed function" 29 "HPA043019: , HPA043586: " "unprognostic (3.16e-1)" "unprognostic (1.07e-1)" "unprognostic (3.16e-1)" "unprognostic (6.83e-2)" "unprognostic (1.75e-1)" "unprognostic (6.93e-2)" "unprognostic (1.74e-1)" "unprognostic (4.95e-2)" "unprognostic (1.92e-2)" "unprognostic (3.22e-2)" "unprognostic (1.70e-2)" "unprognostic (2.20e-3)" "unprognostic (1.54e-1)" "unprognostic (2.61e-3)" "unprognostic (1.05e-1)" "unprognostic (9.35e-2)" "unprognostic (2.65e-1)" "unprognostic (1.01e-2)" "unprognostic (8.88e-3)" "unprognostic (1.15e-2)" "unprognostic (4.25e-1)" "unprognostic (2.39e-2)" "unprognostic (5.98e-2)" "unprognostic (2.06e-1)" "unprognostic (5.58e-2)" "unprognostic (3.43e-2)" "unprognostic (2.40e-1)" "unprognostic (1.19e-1)" "unprognostic (2.71e-2)" "unprognostic (8.85e-2)" "unprognostic (1.57e-1)" CLCNKA hClC-Ka ENSG00000186510 "Chloride voltage-gated channel Ka" P51800 1 16018875-16034050 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel" "Bartter syndrome, Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "kidney: 332.4" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 160.5;Epididymal clear cells: 42.9;Gonadotrophs: 86.4;Late spermatids: 394.7;Loop of henle epithelial cells: 187.8;Renal collecting duct intercalated cells: 123.9;Renal connecting tubule cells: 99.9;Respiratory ionocytes: 40.6" "Group enriched" "Detected in some" 5 "cerebellar inhibitory: 29.3;choroid plexus epithelial cell: 22.2" "Cancer enriched" "Detected in some" 24 "Kidney Chromophobe (TCGA): 64.6" "Group enriched" "Detected in some" 7 "cerebellum: 3.9;choroid plexus: 9.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "thyroid cancer: 7.5" "Adipose visceral - Adipocytes (Visceral), Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary gland ductal cells, Pituitary gland - Gonadotropes, Skin - Eccrine sweat gland cells, Stomach - Parietal cells, Testis - Early spermatids, Testis - Late spermatids" HPA057717 Approved NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 5: Non-specific - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" "HPA057717: " "unprognostic (1.47e-2)" "unprognostic (1.39e-3)" "potential prognostic unfavorable (4.39e-5)" "unprognostic (1.15e-3)" "unprognostic (3.74e-3)" CLCNKB hClC-Kb ENSG00000184908 "Chloride voltage-gated channel Kb" P51801 1 16040252-16057311 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Bartter syndrome, Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "kidney: 125.4;salivary gland: 40.2" "Group enriched" "Detected in some" 5 "Distal convoluted tubule cells: 204.1;Epididymal clear cells: 338.9;Late spermatids: 146.5;Loop of henle epithelial cells: 97.7;Renal collecting duct intercalated cells: 167.4;Renal connecting tubule cells: 107.4;Respiratory ionocytes: 243.8;Salivary ionocytes: 100.2" "Cell type enhanced" "Detected in some" "cerebellar inhibitory: 8.0;choroid plexus epithelial cell: 2.4;upper rhombic lip: 1.9" "Cancer enriched" "Detected in many" 30 "Kidney Chromophobe (TCGA): 485.9" "Region enriched" "Detected in some" 4 "cerebellum: 7.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Kidney - Intercalated cells, Minor Salivary Gland - Minor salivary gland ductal cells, Testis - Late spermatids" HPA057717 Uncertain NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 35: Non-specific - DNA binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" "HPA057717: " "unprognostic (3.78e-1)" "unprognostic (4.55e-2)" "unprognostic (1.16e-1)" "potential prognostic favorable (1.70e-6)" "unprognostic (5.99e-2)" "unprognostic (5.56e-3)" "unprognostic (1.81e-1)" "unprognostic (1.53e-1)" "unprognostic (5.05e-1)" "unprognostic (6.86e-3)" "unprognostic (5.76e-3)" CLDN1 "ILVASC, SEMP1" ENSG00000163347 "Claudin 1" O95832 3 190305707-190322446 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" Ichthyosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 289.7;skin 1: 275.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 425.7;Epididymal basal cells: 2094.0;Epididymal efferent duct ciliated cells: 443.2;Fallopian secretory cells: 412.8;Ocular epithelial cells: 2742.1;Pancreatic duct cells: 502.7;Suprabasal keratinocytes: 879.7;Urothelial cells: 810.5" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 97.5;oligodendrocyte precursor cell: 31.3" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 8 "choroid plexus: 43.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Pancreas - Ductal cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in many" "Region enriched" "Detected in some" 12 "spinal cord: 33.6" "CAB002602, HPA048319" Enhanced NA NA "Cluster 58: Skin - Keratinization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 100: Stratified epithelial cells - Barrier functions" 7 "CAB002602: , HPA048319: " "unprognostic (5.06e-2)" "unprognostic (7.55e-2)" "unprognostic (4.03e-1)" "unprognostic (2.95e-2)" "unprognostic (1.35e-2)" "unprognostic (8.36e-3)" "unprognostic (2.84e-2)" "potential prognostic unfavorable (1.14e-4)" "unprognostic (1.17e-1)" "unprognostic (3.34e-1)" "unprognostic (7.12e-2)" "unprognostic (1.11e-1)" "unprognostic (2.35e-2)" "unprognostic (1.30e-1)" "unprognostic (4.22e-1)" "unprognostic (4.88e-3)" "unprognostic (6.55e-2)" "unprognostic (3.70e-2)" "unprognostic (4.78e-2)" "unprognostic (9.21e-2)" "unprognostic (5.11e-3)" "potential prognostic unfavorable (1.90e-4)" "unprognostic (7.06e-3)" "unprognostic (2.83e-1)" "unprognostic (7.98e-2)" "unprognostic (2.41e-2)" "unprognostic (5.29e-2)" "unprognostic (4.32e-2)" "unprognostic (5.83e-2)" "unprognostic (1.07e-2)" "unprognostic (4.79e-2)" CLDN10 "CPETRL3, OSP-L" ENSG00000134873 "Claudin 10" P78369 13 95433604-95579759 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 73.2;pancreas: 112.3;salivary gland: 80.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 321.7;Endometrial glandular cells: 210.0;Endometrial luminal cells: 244.3;Endometrial secretory cells: 850.8;Epididymal efferent duct absorptive cells: 191.4;Fallopian secretory cells: 242.1;Lacrimal acinar cells: 374.1;Loop of henle epithelial cells: 180.6;Oocytes: 322.4;Pancreatic duct cells: 479.6;Proximal tubule cells: 549.1;Respiratory secretory cells: 178.2;Salivary acinar cells: 351.7" "Group enriched" "Detected in many" 5 "astrocyte: 85.3;Bergmann glia: 95.4;oligodendrocyte precursor cell: 43.3" "Cancer enhanced" "Detected in many" "Pancreatic Adenocarcinoma (TCGA): 44.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "eosinophil: 1.3;neutrophil: 4.1" "Lineage enriched" "Detected in single" 11 "granulocytes: 4.1" "Cancer enriched" "Detected in many" 5 "testis cancer: 67.6" "Adipose subcutaneous - Smooth muscle cells, Liver - Cholangiocytes, Minor Salivary Gland - Minor salivary glandular cells, Skin - Eccrine sweat gland cells, Stomach - Gastric enteroendocrine cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012969, HPA042348" Enhanced NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 8: Pancreas - Proteolysis" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 88: Proximal tubular cells - Transmembrane transport" 14 "CAB012969: , HPA042348: " "unprognostic (1.17e-1)" "unprognostic (8.22e-2)" "unprognostic (2.79e-1)" "unprognostic (1.11e-2)" "unprognostic (4.48e-2)" "potential prognostic unfavorable (3.05e-4)" "unprognostic (3.02e-3)" "unprognostic (1.53e-2)" "validated prognostic favorable (4.74e-11)" "validated prognostic favorable (2.35e-4)" "unprognostic (1.18e-1)" "unprognostic (1.79e-2)" "unprognostic (4.74e-2)" "unprognostic (1.84e-1)" "unprognostic (2.28e-1)" "unprognostic (1.07e-1)" "unprognostic (5.34e-2)" "unprognostic (3.48e-2)" "unprognostic (1.28e-1)" "unprognostic (4.97e-3)" "unprognostic (1.27e-1)" "unprognostic (1.68e-1)" "unprognostic (2.32e-1)" "potential prognostic favorable (5.64e-5)" "unprognostic (2.97e-2)" "unprognostic (8.14e-2)" "potential prognostic favorable (3.07e-5)" "unprognostic (3.25e-2)" CLDN11 "OSP, OTM" ENSG00000013297 "Claudin 11" O75508 3 170418868-170454733 "Disease related genes, Human disease related genes, Predicted membrane proteins" Leukodystrophy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 119.5;ovary: 46.0;testis: 50.6" "Cell type enhanced" "Detected in some" "Oligodendrocytes: 2.8;Ovarian stromal cells: 1.8;Sertoli cells: 1.4" "Cell type enhanced" "Detected in some" "fibroblast: 1.1;oligodendrocyte: 3.7" "Cancer enriched" "Detected in some" 5 "Glioblastoma Multiforme (TCGA): 10.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "ovarian cancer: 29.3" "Adrenal gland - Fibroblasts, Pituitary gland - Fibroblasts, Prostate - Fibroblasts, Stomach - Fibroblasts, Testis - Sertoli cells" "Region enriched" "Detected in all" 5 "white matter: 2085.3" "Low region specificity" "Detected in all" "CAB009789, HPA013166, HPA013657" Enhanced Approved "Lipid droplets,Cell Junctions" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 94: Gonadal somatic cells - Mixed function" 9 "Lipid droplets, Cell Junctions" "CAB009789: , HPA013166: , HPA013657: " "unprognostic (2.95e-1)" "unprognostic (1.45e-2)" "unprognostic (5.49e-2)" "unprognostic (2.69e-3)" "unprognostic (5.09e-2)" "unprognostic (1.16e-1)" "unprognostic (1.14e-1)" "unprognostic (2.54e-2)" "unprognostic (2.14e-1)" "unprognostic (2.46e-1)" CLDN12 ENSG00000157224 "Claudin 12" P56749 7 90383721-90513402 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 42.1;Early spermatids: 92.7;Late primary spermatocytes: 53.6;Loop of henle epithelial cells: 34.3;Podocytes: 31.2;Proximal tubule cells: 44.7;Renal collecting duct intercalated cells: 28.3;Renal collecting duct principal cells: 28.4;Renal connecting tubule cells: 25.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" HPA026945 Approved NA NA "Cluster 76: Non-specific - Metabolism" "Cluster 1: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" "HPA026945: " "unprognostic (6.55e-3)" "unprognostic (1.63e-1)" "unprognostic (6.42e-2)" "potential prognostic unfavorable (1.99e-5)" "unprognostic (6.98e-2)" "unprognostic (2.26e-1)" "unprognostic (1.07e-1)" "unprognostic (6.51e-3)" "unprognostic (2.39e-2)" "unprognostic (1.39e-2)" "potential prognostic favorable (1.21e-5)" "unprognostic (3.06e-2)" "unprognostic (2.45e-1)" "unprognostic (3.31e-2)" "unprognostic (6.06e-2)" "unprognostic (1.74e-3)" "potential prognostic unfavorable (2.89e-4)" "unprognostic (2.65e-1)" "unprognostic (1.66e-1)" "unprognostic (1.36e-1)" "unprognostic (1.13e-2)" "unprognostic (1.68e-2)" "unprognostic (4.83e-2)" "unprognostic (1.71e-1)" "unprognostic (2.11e-1)" "unprognostic (5.62e-3)" "unprognostic (3.56e-1)" "unprognostic (1.24e-1)" "unprognostic (3.31e-1)" "unprognostic (4.80e-2)" "unprognostic (2.73e-1)" CLDN14 DFNB29 ENSG00000159261 "Claudin 14" O95500 21 36460621-36576569 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 39.4" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 19.6;Early spermatids: 17.5;Epididymal principal cells: 43.9;Hepatocytes: 34.4;Loop of henle epithelial cells: 117.7;Myonuclei: 17.7;Pancreatic duct cells: 13.4;Plasma cells: 17.7" "Cell type enhanced" "Detected in some" "endothelial cell: 3.6" "Group enriched" "Detected in many" 4 "Liver Hepatocellular Carcinoma (TCGA): 18.6;Skin Cutaneous Melanoma (TCGA): 5.1" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lymphoma: 7.9" "Liver - Hepatocytes, Skin - Hair cortex cells, Skin - Inner root sheath cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA054707 Uncertain Vesicles NA NA "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 4 Vesicles "HPA054707: " "unprognostic (9.14e-2)" "unprognostic (2.57e-1)" "potential prognostic favorable (3.29e-4)" "unprognostic (1.55e-1)" "unprognostic (2.07e-1)" "unprognostic (7.62e-2)" "unprognostic (1.37e-1)" "potential prognostic unfavorable (4.48e-4)" "unprognostic (5.31e-2)" "unprognostic (4.42e-2)" "potential prognostic favorable (1.87e-4)" "unprognostic (2.63e-2)" "unprognostic (1.84e-2)" "unprognostic (1.87e-1)" "unprognostic (1.43e-1)" "unprognostic (7.75e-2)" "unprognostic (1.28e-1)" "unprognostic (1.83e-2)" "unprognostic (3.94e-2)" CLDN15 ENSG00000106404 "Claudin 15" P56746 7 101232092-101238820 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "adipose tissue: 69.3;intestine: 244.4" "Cell type enhanced" "Detected in many" "Enteric stem cells: 121.0;Enteric transient amplifying cells: 146.6;Enterocytes: 563.9;Mesothelial cells: 127.5;Paneth cells: 177.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 77: Intestine - Digestion" "Cluster 11: White matter - Signal transduction" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 1: Enterocytes - Absorption and Digestion" "unprognostic (1.84e-2)" "unprognostic (1.76e-2)" "unprognostic (1.70e-2)" "unprognostic (2.54e-2)" "unprognostic (5.40e-3)" "unprognostic (1.77e-1)" "unprognostic (8.87e-2)" "unprognostic (9.97e-2)" "unprognostic (4.34e-2)" "unprognostic (1.38e-1)" "unprognostic (1.74e-2)" "unprognostic (8.51e-2)" "unprognostic (2.51e-2)" "unprognostic (1.80e-2)" "unprognostic (1.35e-1)" "unprognostic (2.08e-1)" "unprognostic (1.84e-1)" "unprognostic (8.69e-2)" "unprognostic (8.66e-3)" "unprognostic (7.55e-2)" "unprognostic (9.65e-3)" "potential prognostic favorable (1.26e-4)" "unprognostic (2.76e-1)" "unprognostic (2.98e-2)" "unprognostic (1.43e-1)" "unprognostic (4.51e-2)" "unprognostic (1.18e-1)" "unprognostic (1.81e-1)" "unprognostic (4.56e-2)" "unprognostic (2.56e-2)" "unprognostic (1.15e-1)" CLDN16 "HOMG3, PCLN1" ENSG00000113946 "Claudin 16" Q9Y5I7 3 190322541-190412138 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Disease variant, Primary hypomagnesemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "kidney: 59.3" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 83.1;Epicardial cells: 34.1;Epididymal basal cells: 122.2;Epididymal efferent duct ciliated cells: 66.7;Loop of henle epithelial cells: 89.9;Ocular epithelial cells: 194.0;Respiratory ciliated cells: 99.2" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 64.3" "Group enriched" "Detected in many" 13 "Ovary Serous Cystadenocarcinoma (TCGA): 68.9;Thyroid Carcinoma (TCGA): 59.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 10 "ovarian cancer: 120.3;Uterine cancer: 175.0" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal cortex cells, Kidney - Ascending Loop of Henle cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA056020 Enhanced NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 100: Stratified epithelial cells - Barrier functions" "HPA056020: " "unprognostic (5.24e-2)" "unprognostic (8.85e-2)" "unprognostic (4.20e-2)" "unprognostic (1.63e-1)" "unprognostic (1.73e-2)" "unprognostic (3.11e-2)" "unprognostic (4.80e-2)" "unprognostic (1.58e-1)" "unprognostic (8.49e-2)" "unprognostic (5.61e-3)" "unprognostic (3.69e-2)" "unprognostic (3.62e-3)" CLDN17 "MGC126552, MGC126554" ENSG00000156282 "Claudin 17" P56750 21 30165565-30166805 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "cervix: 6.4;esophagus: 6.1;salivary gland: 5.5;vagina: 6.9" "Cell type enriched" "Detected in some" 21 "Esophageal apical cells: 95.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Head and Neck Squamous Cell Carcinoma (TCGA): 3.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA045903 Enhanced NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 1 "HPA045903: " "unprognostic (2.30e-1)" CLDN18 SFTPJ ENSG00000066405 "Claudin 18" P56856 3 137998735-138033655 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 51 "lung: 237.8;stomach 1: 684.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 871.0;Alveolar cells type 2: 488.9;Foveolar cells: 2380.6;Gastric chief cells: 400.8;Gastric progenitor cells: 380.7;Mucous neck cells: 609.5;Parietal cells: 753.1;Transitional alveolar cells: 313.5" "Cell type enhanced" "Detected in many" "ependymal cell: 12.9" "Group enriched" "Detected in some" 7 "Pancreatic Adenocarcinoma (TCGA): 178.0;Stomach Adenocarcinoma (TCGA): 285.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 17.9;pancreatic cancer: 12.4" "Lung - Alveolar cells type 1, Testis - Spermatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "CAB013010, CAB013243, HPA018446" Enhanced Approved "Cell Junctions" NA NA "Cluster 60: Stomach - Digestion" "Cluster 17: Choroid plexus - Cilium" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 68: Foveolar cells - Mucosal defense" 2 "Cell Junctions" "CAB013010: , CAB013243: , HPA018446: " "unprognostic (1.72e-1)" "unprognostic (3.78e-1)" "unprognostic (2.97e-2)" "unprognostic (1.93e-3)" "unprognostic (1.00e-1)" "unprognostic (1.06e-2)" "unprognostic (3.35e-1)" "unprognostic (3.21e-2)" "unprognostic (1.55e-3)" "unprognostic (1.84e-2)" "unprognostic (1.26e-1)" "unprognostic (2.42e-1)" CLDN19 ENSG00000164007 "Claudin 19" Q8N6F1 1 42733093-42740254 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Sensory transduction, Vision" "Disease variant, Primary hypomagnesemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 12.2;kidney: 42.4;placenta: 9.2" "Group enriched" "Detected in some" 4 "Extravillous trophoblasts: 360.7;Retinal pigment epithelial cells: 98.0" "Cell type enriched" "Detected in single" 11 "choroid plexus epithelial cell: 4.3" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 7.2" "Region enriched" "Detected in many" 14 "choroid plexus: 43.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 2.9;testis cancer: 3.2" "Breast - Breast myoepithelial cells, Kidney - Ascending Loop of Henle cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells" "Region enhanced" "Detected in many" "olfactory bulb: 5.4" "Region enriched" "Detected in all" 5 "spinal cord: 89.7" HPA014412 Supported "Plasma membrane" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" "Plasma membrane" "HPA014412: " "unprognostic (2.19e-1)" "unprognostic (1.94e-2)" "unprognostic (4.50e-2)" "unprognostic (1.98e-1)" "unprognostic (3.59e-2)" "unprognostic (1.19e-2)" "unprognostic (2.75e-1)" "unprognostic (1.85e-1)" "unprognostic (9.88e-2)" "unprognostic (2.05e-2)" CLDN2 ENSG00000165376 "Claudin 2" P57739 X 106900164-106930861 "Disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 189.2;gallbladder: 95.3;kidney: 154.2;seminal vesicle: 85.1" "Cell type enriched" "Detected in some" 6 "Epididymal efferent duct absorptive cells: 351.7" "Cell type enriched" "Detected in some" 19 "choroid plexus epithelial cell: 70.9" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 221.1" "Region enriched" "Detected in many" 13 "choroid plexus: 243.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 127.7;Kidney cancer: 98.9" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Kidney - Proximal tubular cells" "Group enriched" "Detected in many" 4 "basal ganglia: 4.5;hippocampal formation: 9.5;pons and medulla: 10.3;thalamus: 8.9" "Low region specificity" "Detected in many" "CAB002609, HPA051548, HPA074528" Enhanced Supported "Nucleoplasm,Nucleoli,Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 20 "Plasma membrane, Cell Junctions" "Nucleoplasm, Nucleoli, Vesicles" "CAB002609: , HPA051548: , HPA074528: " "unprognostic (1.12e-1)" "unprognostic (2.45e-2)" "unprognostic (3.34e-1)" "unprognostic (3.64e-1)" "potential prognostic favorable (8.01e-6)" "unprognostic (7.56e-3)" "unprognostic (9.58e-3)" "unprognostic (7.70e-2)" "unprognostic (8.67e-3)" "potential prognostic favorable (6.58e-5)" "unprognostic (8.02e-2)" "unprognostic (1.23e-2)" "unprognostic (1.78e-1)" "unprognostic (5.45e-2)" "unprognostic (1.43e-2)" "unprognostic (1.06e-1)" "potential prognostic unfavorable (8.77e-4)" "unprognostic (2.09e-1)" "unprognostic (1.52e-1)" "potential prognostic favorable (2.00e-4)" "unprognostic (6.34e-2)" CLDN20 ENSG00000171217 "Claudin 20" P56880 6 155264013-155276548 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in single" "Cell type enhanced" "Detected in many" "Adipocytes: 21.4;Cardiomyocytes: 87.3;Epicardial cells: 25.0;Mast cells: 13.8;Myonuclei: 24.6;Retinal horizontal cells: 14.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in single" "Lung Squamous Cell Carcinoma (TCGA): 1.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Skin - Outer root sheath cells" "Low region specificity" "Detected in all" HPA073105 Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 40: Non-specific - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 56: Non-specific - Sensory perception" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 4 "Golgi apparatus, Plasma membrane" Cytosol "HPA073105: " "unprognostic (3.37e-1)" "unprognostic (3.52e-2)" "unprognostic (1.66e-2)" "unprognostic (1.31e-3)" "unprognostic (1.76e-2)" CLDN22 CLDN21 ENSG00000177300 "Claudin 22" Q8N7P3 4 183318100-183320276 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "salivary gland: 6.9" "Cell type enriched" "Detected in some" 5 "Endometrial luminal cells: 135.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Ovary Serous Cystadenocarcinoma (TCGA): 3.7;Uterine Corpus Endometrial Carcinoma (TCGA): 6.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 82: Salivary gland - Secretion" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 5 "potential prognostic favorable (9.49e-4)" "unprognostic (2.24e-2)" "unprognostic (2.19e-1)" "unprognostic (5.56e-2)" "unprognostic (1.30e-2)" "potential prognostic unfavorable (6.66e-5)" CLDN23 CLDNL ENSG00000253958 "Claudin 23" Q96B33 8 8701937-8704096 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 15.4;stomach 1: 14.8" "Cell type enhanced" "Detected in some" "Microglia: 1.9;Papillary tip epithelial cells: 4.4;Podocytes: 1.0;Renal collecting duct principal cells: 1.2" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 1.6;endothelial cell: 1.3;ependymal cell: 1.0" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in some" 4 "choroid plexus: 4.6" "Immune cell enhanced" "Detected in some" "myeloid DC: 1.3;plasmacytoid DC: 1.4" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Pancreas - Ductal cells, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA061306 Approved "Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 77: Intestine - Digestion" "Cluster 8: Immune cells - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 1 Vesicles "Plasma membrane, Cell Junctions" "HPA061306: " "unprognostic (1.36e-1)" "unprognostic (8.05e-2)" "unprognostic (1.07e-2)" "unprognostic (3.81e-2)" "unprognostic (7.38e-2)" "unprognostic (1.35e-3)" "unprognostic (1.91e-3)" "unprognostic (8.40e-2)" "unprognostic (2.93e-1)" "unprognostic (1.03e-1)" "unprognostic (2.37e-2)" "unprognostic (4.25e-2)" "unprognostic (1.35e-1)" "unprognostic (2.19e-2)" "unprognostic (1.02e-1)" "unprognostic (7.40e-2)" "unprognostic (1.80e-3)" "potential prognostic unfavorable (3.63e-4)" "unprognostic (1.05e-2)" "unprognostic (2.97e-2)" "unprognostic (1.87e-1)" "unprognostic (1.63e-1)" "unprognostic (1.94e-2)" "unprognostic (2.41e-1)" "unprognostic (9.36e-2)" "unprognostic (7.06e-2)" "unprognostic (7.95e-2)" "unprognostic (4.79e-1)" "unprognostic (3.24e-2)" "unprognostic (9.75e-2)" CLDN24 CLDN21 ENSG00000185758 "Claudin 24" A6NM45 4 183321764-183322426 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "lymphoma: 2.7" "Minor Salivary Gland - Minor salivary glandular cells" NA NA "Cluster 32: Cerebral cortex - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" CLDN25 ENSG00000228607 "Claudin 25" C9JDP6 11 113779796-113780485 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 45 "Respiratory ionocytes: 55.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA053555 Uncertain NA NA "Cluster 50: Lymphoma - Unknown function" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" "HPA053555: " CLDN3 "C7orf1, CPE-R2, CPETR2, HRVP1, RVP1" ENSG00000165215 "Claudin 3" O15551 7 73768997-73770270 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cancer-related genes, Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 248.6;pancreas: 92.7;thyroid gland: 110.9" "Cell type enhanced" "Detected in many" "Breast secretory cells: 680.6;Colonocytes: 2780.7;Endometrial ciliated cells: 975.5;Endometrial glandular cells: 1468.5;Endometrial luminal cells: 1459.2;Enteric stem cells: 1410.9;Enteric transient amplifying cells: 1531.7;Enterocytes: 2815.1;Fallopian tube ciliated cells: 768.0;Goblet cells: 1660.3;Paneth cells: 935.9" "Group enriched" "Detected in some" 4 "choroid plexus epithelial cell: 27.3;ependymal cell: 16.9" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 710.4" "Region enriched" "Detected in all" 8 "choroid plexus: 81.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 169.1" "Breast - Breast glandular cells, Colon - Colon enterocytes, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Stomach - Gastric enteroendocrine cells" "Region enhanced" "Detected in single" "basal ganglia: 1.5" HPA014361 Enhanced Supported "Cell Junctions" NA NA "Cluster 17: Intestine - Digestion" "Cluster 36: Choroid plexus - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" "Cell Junctions" "HPA014361: " "unprognostic (1.55e-1)" "unprognostic (2.30e-1)" "unprognostic (1.79e-1)" "potential prognostic favorable (6.55e-4)" "unprognostic (2.58e-1)" "unprognostic (8.50e-3)" "unprognostic (8.09e-2)" "potential prognostic favorable (8.51e-6)" "potential prognostic favorable (6.29e-5)" "unprognostic (7.53e-3)" "potential prognostic favorable (3.39e-5)" "unprognostic (3.00e-2)" "unprognostic (1.61e-1)" "unprognostic (1.70e-1)" "unprognostic (2.77e-1)" "unprognostic (9.94e-3)" "unprognostic (2.77e-2)" "unprognostic (1.11e-2)" "unprognostic (2.80e-1)" "unprognostic (1.86e-3)" "unprognostic (1.97e-2)" "unprognostic (2.95e-1)" "unprognostic (2.53e-1)" "unprognostic (2.58e-1)" "unprognostic (3.00e-2)" "unprognostic (2.60e-1)" "unprognostic (1.58e-2)" "unprognostic (9.35e-3)" CLDN34 ENSG00000234469 "Claudin 34" H7C241 X 9967358-9968352 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "testis: 1.6" "Group enriched" "Detected in some" 8 "Early spermatids: 11.3;Late primary spermatocytes: 10.1;Late spermatids: 8.3;Retinal ganglion cells: 3.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" NA NA "Cluster 47: Testis - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" CLDN4 "CPE-R, CPETR, CPETR1, hCPE-R, WBSCR8" ENSG00000189143 "Claudin 4" O14493 7 73799542-73832690 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Cancer-related genes, Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 317.9;intestine: 265.3;urinary bladder: 282.7" "Cell type enhanced" "Detected in many" "Breast secretory cells: 2532.4;Colonocytes: 2493.7;Endometrial glandular cells: 2506.9;Endometrial luminal cells: 1852.0;Enterocytes: 1748.9;Epididymal basal cells: 4215.3;Esophageal apical cells: 5918.8;Esophageal suprabasal cells: 2044.2;Ocular epithelial cells: 3934.8;Urothelial cells: 3469.6" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 16.5;ependymal cell: 13.2" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "choroid plexus: 11.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 992.2" "Colon - Colon enterocytes, Liver - Cholangiocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Ductal cells, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Not detected" "Not detected" CAB002610 Enhanced Supported "Plasma membrane" NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 17: Choroid plexus - Cilium" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 14 "Plasma membrane" "CAB002610: " "unprognostic (2.09e-1)" "unprognostic (2.59e-1)" "unprognostic (7.79e-2)" "unprognostic (1.65e-1)" "unprognostic (6.37e-2)" "unprognostic (7.83e-2)" "unprognostic (2.09e-1)" "unprognostic (1.40e-1)" "validated prognostic favorable (1.95e-9)" "validated prognostic favorable (5.05e-5)" "unprognostic (1.34e-1)" "unprognostic (8.54e-3)" "unprognostic (2.87e-2)" "unprognostic (7.40e-2)" "unprognostic (5.73e-3)" "unprognostic (8.48e-2)" "unprognostic (6.19e-2)" "potential prognostic unfavorable (2.30e-4)" "unprognostic (5.77e-2)" "unprognostic (3.90e-3)" "unprognostic (3.49e-1)" "unprognostic (2.66e-1)" "unprognostic (4.43e-2)" "unprognostic (1.26e-1)" "unprognostic (1.72e-1)" "unprognostic (9.81e-2)" "unprognostic (1.55e-1)" "unprognostic (1.14e-1)" "unprognostic (1.03e-1)" CLDN5 "AWAL, BEC1, CPETRL1, TMVCF" ENSG00000184113 "Claudin 5" O00501 22 19523024-19527545 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 424.4;breast: 412.2;choroid plexus: 406.9;lung: 384.3" "Group enriched" "Detected in many" 7 "Lymphatic endothelial cells: 1226.8;Platelets: 626.7;Vascular endothelial cells: 710.8" "Cell type enriched" "Detected in many" 8 "endothelial cell: 1608.8" "Cancer enriched" "Detected in all" 4 "Glioblastoma Multiforme (TCGA): 131.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 24 "basophil: 19.0;naive CD4 T-cell: 4.8;neutrophil: 5.9" "Group enriched" "Detected in many" 29 "granulocytes: 19.0;T-cells: 4.8" "Cancer enhanced" "Detected in some" "Bone cancer: 6.4;cervical cancer: 13.7" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Prostate - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB002607 Approved NA NA 230000 "Cluster 4: Neutrophils - Degranulation" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 33 "CAB002607: " "unprognostic (3.69e-2)" "unprognostic (6.97e-2)" "unprognostic (3.90e-2)" "potential prognostic favorable (5.01e-4)" "unprognostic (4.48e-2)" "unprognostic (1.63e-1)" "unprognostic (1.08e-2)" "unprognostic (2.91e-1)" "unprognostic (1.17e-1)" "unprognostic (8.02e-2)" "potential prognostic favorable (3.97e-4)" "unprognostic (1.38e-3)" "unprognostic (9.05e-3)" "unprognostic (9.64e-2)" "unprognostic (5.56e-3)" "unprognostic (2.51e-1)" "unprognostic (4.18e-1)" "potential prognostic unfavorable (2.57e-5)" "unprognostic (2.48e-1)" "unprognostic (3.60e-2)" "unprognostic (2.01e-1)" "unprognostic (4.98e-3)" "unprognostic (8.80e-2)" "unprognostic (1.64e-1)" "unprognostic (5.64e-2)" "unprognostic (6.76e-2)" "unprognostic (3.58e-1)" "unprognostic (1.55e-2)" "unprognostic (3.85e-2)" "unprognostic (1.10e-1)" "unprognostic (2.73e-1)" CLDN6 ENSG00000184697 "Claudin 6" P56747 16 3014712-3020071 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.0;pancreas: 1.0" "Group enriched" "Detected in many" 4 "Extravillous trophoblasts: 174.3;Migrating cytotrophoblasts: 156.7" "Low cell type specificity" "Detected in single" "Group enriched" "Detected in many" 5 "Ovary Serous Cystadenocarcinoma (TCGA): 143.3;Testicular Germ Cell Tumor (TCGA): 231.0;Uterine Corpus Endometrial Carcinoma (TCGA): 67.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "testis cancer: 303.0" "Pancreas - Ductal cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 70: Non-specific - Protein processing" "Cluster 15: Non-specific - Transcription" "Cluster 34: Testis cancer - Unknown function" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 7 "unprognostic (4.94e-3)" "unprognostic (2.61e-1)" "unprognostic (1.08e-1)" "unprognostic (1.13e-1)" "unprognostic (3.16e-1)" "unprognostic (4.33e-2)" "unprognostic (1.37e-1)" "unprognostic (6.17e-2)" "unprognostic (2.70e-2)" "unprognostic (9.49e-3)" "unprognostic (3.40e-1)" "unprognostic (4.45e-1)" "unprognostic (1.83e-3)" "unprognostic (1.32e-3)" "unprognostic (1.47e-1)" "unprognostic (2.76e-2)" CLDN7 "CEPTRL2, CPETRL2, Hs.84359" ENSG00000181885 "Claudin 7" O95471 17 7259903-7263983 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 324.6;intestine: 321.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 72.5;Alveolar cells type 2: 36.1;Breast secretory cells: 37.4;Colonocytes: 34.1;Conjunctival goblet cells: 35.0;Endometrial secretory cells: 54.1;Enterocytes: 52.9;Esophageal apical cells: 61.9;Ocular epithelial cells: 34.3;Respiratory deuterosomal cells: 41.5" "Cell type enhanced" "Detected in single" "central nervous system macrophage: 1.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Pancreas - Ductal cells, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB013063, HPA014703, HPA073662" Enhanced Approved "Vesicles,Cell Junctions" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 61 Vesicles "Cell Junctions" "CAB013063: , HPA014703: , HPA073662: " "unprognostic (4.18e-2)" "unprognostic (2.01e-2)" "unprognostic (2.39e-1)" "unprognostic (8.84e-2)" "unprognostic (4.33e-2)" "unprognostic (4.21e-3)" "unprognostic (2.83e-2)" "unprognostic (9.94e-2)" "unprognostic (1.72e-1)" "unprognostic (1.77e-1)" "unprognostic (2.89e-2)" "unprognostic (1.11e-2)" "potential prognostic favorable (9.52e-7)" "unprognostic (5.73e-2)" "unprognostic (5.49e-3)" "unprognostic (1.52e-2)" "unprognostic (6.70e-2)" "unprognostic (2.03e-1)" "unprognostic (1.27e-1)" "unprognostic (8.56e-2)" "unprognostic (9.55e-2)" "unprognostic (3.35e-3)" "unprognostic (1.89e-1)" "unprognostic (3.76e-2)" "unprognostic (2.50e-2)" "unprognostic (2.82e-2)" "potential prognostic unfavorable (8.39e-4)" "unprognostic (1.04e-3)" "unprognostic (2.00e-1)" "potential prognostic favorable (1.11e-4)" "unprognostic (3.85e-2)" CLDN8 ENSG00000156284 "Claudin 8" P56748 21 30214006-30216097 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 64.5;intestine: 47.8;kidney: 64.7;salivary gland: 37.8" "Cell type enhanced" "Detected in some" "Breast lactating cells: 89.6;Breast secretory cells: 57.1;Colonocytes: 74.5;Lacrimal acinar cells: 37.1;Prostatic hillock cells: 33.2;Renal collecting duct intercalated cells: 54.0;Renal collecting duct principal cells: 71.1;Respiratory ciliated cells: 47.4;Salivary acinar cells: 46.6;Salivary basal cells: 33.6;Salivary duct cells: 102.9;Salivary ionocytes: 108.9" "Not detected" "Not detected" "Group enriched" "Detected in many" 9 "Kidney Chromophobe (TCGA): 169.2;Prostate Adenocarcinoma (TCGA): 45.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 10.6;prostate cancer: 8.7" "Colon - Colon enterocytes, Kidney - Intercalated cells, Lung - Respiratory ciliated cells, Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA060605 Approved NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 9 "HPA060605: " "unprognostic (2.79e-1)" "unprognostic (2.57e-1)" "unprognostic (1.80e-1)" "unprognostic (1.11e-3)" "unprognostic (2.09e-2)" "unprognostic (9.79e-3)" "unprognostic (7.01e-2)" "unprognostic (3.25e-3)" "unprognostic (6.07e-1)" "unprognostic (8.85e-2)" "unprognostic (2.98e-1)" "unprognostic (1.65e-1)" "unprognostic (3.20e-1)" "unprognostic (3.87e-1)" "unprognostic (3.05e-1)" "unprognostic (2.94e-2)" "unprognostic (1.82e-1)" CLDN9 ENSG00000213937 "Claudin 9" O95484 16 3012923-3014505 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 27.1;pituitary gland: 28.6" "Cell type enhanced" "Detected in some" "Cholangiocytes: 17.7;Corticotrophs: 39.4;Endometrial ciliated cells: 10.4;Endometrial secretory cells: 7.8;Epididymal basal cells: 13.5;Epididymal clear cells: 8.2;Epididymal efferent duct ciliated cells: 15.5;Fallopian secretory cells: 7.6;Fallopian tube ciliated cells: 9.8;Gonadotrophs: 10.3;Pancreatic duct cells: 31.2;Respiratory ciliated cells: 11.9" "Cell type enhanced" "Detected in some" "upper rhombic lip: 4.8" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 18.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Pancreas - Ductal cells, Spleen - Neutrophils_2" "Not detected" "Not detected" "Region enhanced" "Detected in single" "basal ganglia: 1.3" HPA076613 Supported "Vesicles,Cell Junctions" NA NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 37: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 17 "Cell Junctions" Vesicles "HPA076613: " "unprognostic (8.56e-2)" "unprognostic (4.38e-2)" "unprognostic (1.98e-1)" "unprognostic (8.67e-2)" "unprognostic (5.76e-3)" "unprognostic (1.04e-1)" "unprognostic (9.70e-2)" "unprognostic (4.23e-3)" "unprognostic (1.04e-1)" "unprognostic (1.19e-2)" "unprognostic (1.50e-1)" "unprognostic (6.23e-2)" "unprognostic (2.32e-3)" "unprognostic (3.76e-2)" "unprognostic (5.04e-2)" "unprognostic (4.56e-3)" "unprognostic (1.13e-2)" "unprognostic (1.07e-1)" "unprognostic (2.40e-1)" "unprognostic (2.33e-3)" "unprognostic (2.62e-1)" "unprognostic (6.43e-3)" "unprognostic (1.19e-3)" CLDND1 "C3orf4, Z38" ENSG00000080822 "Claudin domain containing 1" Q9NY35 3 98497912-98523066 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 14 "brain: 1440.2" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 693.2;Extravillous trophoblasts: 235.1;Late primary spermatocytes: 267.7;Oligodendrocytes: 681.9" "Cell type enriched" "Detected in all" 4 "oligodendrocyte: 911.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029841 Approved Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 59: Leukemia - T-cell receptor" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 6 Nucleoplasm "Nucleoli, Cytosol" "HPA029841: " "unprognostic (2.28e-1)" "unprognostic (1.24e-1)" "unprognostic (3.84e-2)" "unprognostic (3.13e-1)" "unprognostic (9.27e-2)" "unprognostic (1.67e-1)" "unprognostic (1.84e-1)" "unprognostic (1.29e-1)" "unprognostic (1.57e-1)" "unprognostic (2.39e-2)" "potential prognostic favorable (6.53e-4)" "unprognostic (2.26e-2)" "unprognostic (1.97e-2)" "unprognostic (1.52e-3)" "unprognostic (1.36e-1)" "unprognostic (2.66e-3)" "unprognostic (1.43e-2)" "unprognostic (2.99e-1)" "unprognostic (1.03e-1)" "unprognostic (1.02e-1)" "unprognostic (8.44e-2)" "unprognostic (8.71e-2)" "unprognostic (1.94e-3)" "unprognostic (6.80e-2)" "unprognostic (2.12e-1)" "unprognostic (1.85e-1)" "unprognostic (1.13e-1)" "potential prognostic unfavorable (1.34e-5)" "unprognostic (2.54e-1)" "unprognostic (3.30e-2)" "unprognostic (3.26e-1)" CLDND2 MGC33839 ENSG00000160318 "Claudin domain containing 2" Q8NHS1 19 51367098-51369003 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 43.1" "Group enriched" "Detected in some" 19 "Early spermatids: 263.8;Late primary spermatocytes: 282.8" "Cell type enhanced" "Detected in single" "fibroblast: 1.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA056971 Uncertain Approved Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 35: RS4;11 - Unknown function" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 24 Nucleoplasm "HPA056971: " "unprognostic (2.66e-2)" "unprognostic (3.01e-1)" "unprognostic (1.24e-1)" "potential prognostic favorable (7.45e-4)" "unprognostic (1.77e-3)" "unprognostic (6.53e-2)" "unprognostic (2.83e-1)" "unprognostic (7.55e-2)" "unprognostic (2.83e-1)" "unprognostic (2.18e-1)" "potential prognostic unfavorable (5.33e-5)" "unprognostic (4.76e-2)" "unprognostic (1.65e-1)" "potential prognostic unfavorable (3.05e-4)" "unprognostic (2.39e-2)" "unprognostic (1.01e-2)" "unprognostic (3.61e-1)" "unprognostic (5.61e-2)" "unprognostic (2.38e-1)" "unprognostic (2.36e-1)" "unprognostic (1.72e-3)" "unprognostic (7.44e-3)" "unprognostic (6.89e-2)" "unprognostic (1.05e-1)" "unprognostic (5.59e-2)" "unprognostic (2.31e-1)" "unprognostic (1.94e-1)" "unprognostic (1.17e-1)" "unprognostic (1.58e-1)" CLEC10A "CD301, CLECSF13, CLECSF14, HML, HML2" ENSG00000132514 "C-type lectin domain containing 10A" Q8IUN9 17 7074537-7080307 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Endocytosis, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 27.7" "Cell type enriched" "Detected in some" 5 "cDC: 662.6" "Cell type enriched" "Detected in single" 5 "leukocyte: 4.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 12 "myeloid DC: 466.5" "Lineage enriched" "Detected in many" 12 "dendritic cells: 466.5" "Not detected" "Not detected" "Breast - Macrophages, Heart muscle - Macrophages, Skeletal muscle - Macrophages" "Not detected" "Not detected" HPA021937 Approved NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 82: Dendritic cells - Antigen presentation" 25 "HPA021937: " "unprognostic (1.21e-2)" "unprognostic (3.41e-3)" "potential prognostic favorable (2.75e-5)" "unprognostic (3.52e-3)" "unprognostic (2.59e-1)" "unprognostic (1.29e-1)" "unprognostic (7.35e-3)" "unprognostic (2.29e-1)" "potential prognostic favorable (5.61e-6)" "unprognostic (3.13e-2)" "unprognostic (1.88e-1)" "unprognostic (1.79e-1)" "unprognostic (1.37e-1)" "unprognostic (4.10e-2)" "potential prognostic favorable (3.24e-6)" "unprognostic (2.39e-1)" "unprognostic (6.68e-2)" "unprognostic (8.08e-2)" "unprognostic (1.55e-1)" "unprognostic (1.13e-1)" "unprognostic (7.16e-2)" "unprognostic (3.04e-1)" "unprognostic (1.30e-1)" "unprognostic (2.40e-3)" "unprognostic (1.07e-1)" "unprognostic (1.17e-1)" "unprognostic (2.63e-1)" "unprognostic (5.13e-2)" "unprognostic (2.62e-1)" "unprognostic (2.37e-1)" CLEC11A "CLECSF3, LSLCL, P47, SCGF" ENSG00000105472 "C-type lectin domain containing 11A" Q9Y240 19 50723364-50725708 "Plasma proteins, Predicted secreted proteins" Osteogenesis "Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 109.3" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 138.6;Epididymal efferent duct absorptive cells: 397.4;Hematopoietic stem cells: 107.2;Hepatic stellate cells: 161.4;Megakaryocyte progenitors: 155.0;Megakaryocyte-Erythroid progenitors: 117.1;Monocyte progenitors: 172.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 24.1" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Leukemia: 306.3" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblasts_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblasts_1, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA042690 Approved Approved Centrosome "Secreted in other tissues" "Growth factor" NA NA 1100000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 35: RS4;11 - Unknown function" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 58 Centrosome "HPA042690: " "unprognostic (1.39e-3)" "unprognostic (7.09e-2)" "unprognostic (7.95e-2)" "unprognostic (1.82e-1)" "unprognostic (2.97e-3)" "unprognostic (2.60e-2)" "unprognostic (1.04e-1)" "unprognostic (8.16e-2)" "unprognostic (2.04e-2)" "unprognostic (6.43e-2)" "unprognostic (4.73e-2)" "unprognostic (7.42e-2)" "unprognostic (3.15e-2)" "unprognostic (2.89e-2)" "unprognostic (2.70e-2)" "unprognostic (3.50e-1)" "unprognostic (1.54e-1)" "unprognostic (1.13e-2)" "unprognostic (1.68e-1)" "unprognostic (2.83e-2)" "unprognostic (1.78e-2)" "unprognostic (1.12e-1)" "unprognostic (1.49e-1)" "unprognostic (6.24e-2)" "unprognostic (4.34e-2)" "unprognostic (4.72e-2)" "unprognostic (6.11e-2)" "unprognostic (5.11e-2)" "unprognostic (1.07e-2)" "unprognostic (2.30e-2)" "unprognostic (8.22e-3)" CLEC12A "CD371, CLL-1, DCAL-2, MICL" ENSG00000172322 "C-type lectin domain family 12 member A" Q5QGZ9 12 9951316-9995694 "CD markers, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 75.3;lymphoid tissue: 21.4" "Cell type enhanced" "Detected in some" "cDC: 81.8;Kupffer cells: 182.4;Macrophages: 62.8;Mast cells: 78.9;Monocyte progenitors: 160.0;monocytes: 234.0;Neutrophil progenitors: 806.3;Neutrophils: 461.4" "Cell type enriched" "Detected in some" 24 "leukocyte: 91.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 203.3" "Group enriched" "Detected in many" 37 "dendritic cells: 72.7;granulocytes: 203.3;monocytes: 137.1" "Cancer enriched" "Detected in some" 16 "Leukemia: 21.6" "Minor Salivary Gland - Macrophages, Spleen - Neutrophils_2" "Region enriched" "Detected in single" 7 "basal ganglia: 6.2" "Low region specificity" "Detected in single" HPA048515 Enhanced NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 1 "HPA048515: " "unprognostic (2.84e-2)" "unprognostic (1.80e-1)" "unprognostic (2.51e-1)" "unprognostic (6.19e-3)" "unprognostic (9.54e-2)" "unprognostic (3.48e-1)" "unprognostic (2.96e-3)" "unprognostic (1.25e-1)" "unprognostic (5.62e-2)" "unprognostic (3.78e-1)" "unprognostic (1.50e-1)" "unprognostic (1.89e-1)" "unprognostic (6.86e-2)" "potential prognostic favorable (1.84e-4)" "unprognostic (1.14e-1)" "unprognostic (2.71e-1)" "unprognostic (5.06e-1)" "unprognostic (9.41e-2)" "unprognostic (2.04e-1)" "unprognostic (1.90e-1)" "unprognostic (3.15e-2)" "unprognostic (1.23e-1)" "unprognostic (2.51e-1)" "unprognostic (7.69e-2)" "unprognostic (1.18e-2)" "unprognostic (1.54e-1)" "unprognostic (3.68e-2)" CLEC12B ENSG00000256660 "C-type lectin domain family 12 member B" Q2HXU8 12 10010627-10018796 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.2;skin 1: 4.2;testis: 12.5" "Group enriched" "Detected in some" 4 "Melanocytes: 155.8;Sertoli cells: 77.5" "Cell type enhanced" "Detected in some" "leukocyte: 2.0;oligodendrocyte: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 1.4;Rhabdoid: 2.8" "Spleen - Neutrophils_2, Testis - Sertoli cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 39: Testis - Nuclear processes" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 61: Schwann cells & Melanocytes - Mixed function" "unprognostic (6.14e-2)" CLEC14A C14orf27 ENSG00000176435 "C-type lectin domain containing 14A" Q86T13 14 38254000-38256093 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 5 "Vascular endothelial cells: 328.6" "Cell type enriched" "Detected in many" 10 "endothelial cell: 157.6" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 65.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 9 "Leukemia: 8.0" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Pancreas - Endothelial cells, Pituitary gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039468, HPA048119" Uncertain Supported "Endoplasmic reticulum,Golgi apparatus" NA NA 510000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 24 "Endoplasmic reticulum, Golgi apparatus" "HPA039468: , HPA048119: " "unprognostic (1.49e-1)" "unprognostic (2.61e-1)" "unprognostic (3.66e-2)" "unprognostic (1.57e-1)" "unprognostic (1.89e-2)" "unprognostic (9.28e-2)" "unprognostic (1.10e-1)" "unprognostic (4.41e-1)" "potential prognostic favorable (3.34e-5)" "unprognostic (1.23e-1)" "validated prognostic favorable (8.49e-10)" "validated prognostic favorable (2.46e-4)" "potential prognostic unfavorable (7.03e-5)" "unprognostic (3.02e-2)" "unprognostic (1.87e-2)" "unprognostic (7.35e-3)" "unprognostic (3.26e-1)" "unprognostic (4.01e-3)" "unprognostic (1.13e-1)" "unprognostic (4.83e-1)" "unprognostic (4.70e-2)" "unprognostic (4.77e-2)" "unprognostic (1.65e-1)" "unprognostic (2.92e-2)" "unprognostic (1.66e-2)" "unprognostic (1.69e-1)" "unprognostic (7.28e-2)" "unprognostic (2.71e-2)" "unprognostic (1.19e-1)" "unprognostic (7.93e-2)" "unprognostic (3.76e-1)" CLEC16A "Gop-1, KIAA0350" ENSG00000038532 "C-type lectin domain containing 16A" Q2KHT3 16 10944539-11182186 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Autophagy "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Choroid plexus epithelial cells: 432.4;Podocytes: 588.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pituitary gland - Somatotropes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035814, HPA035815, HPA061385" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 67: Testis - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 10 "Nucleoplasm, Vesicles" "HPA035814: , HPA035815: , HPA061385: " "unprognostic (7.31e-2)" "unprognostic (6.43e-2)" "unprognostic (2.35e-1)" "unprognostic (1.65e-1)" "unprognostic (2.95e-1)" "unprognostic (1.03e-1)" "unprognostic (2.55e-1)" "unprognostic (1.02e-3)" "unprognostic (3.36e-2)" "unprognostic (3.52e-1)" "unprognostic (1.78e-1)" "unprognostic (8.63e-2)" "unprognostic (5.04e-2)" "unprognostic (2.48e-1)" "unprognostic (5.04e-1)" "unprognostic (2.39e-2)" "unprognostic (7.07e-2)" "unprognostic (1.69e-1)" "unprognostic (2.53e-1)" "unprognostic (1.04e-2)" "unprognostic (5.37e-2)" "unprognostic (1.21e-1)" "potential prognostic unfavorable (7.74e-5)" "unprognostic (2.67e-2)" "unprognostic (1.14e-1)" "unprognostic (1.59e-1)" "unprognostic (1.50e-1)" "unprognostic (2.42e-1)" "unprognostic (9.11e-2)" "unprognostic (9.37e-2)" "unprognostic (1.57e-1)" CLEC17A FLJ45910 ENSG00000187912 "C-type lectin domain containing 17A" Q6ZS10 19 14583084-14612035 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "intestine: 5.3;lymphoid tissue: 17.1" "Group enriched" "Detected in some" 4 "B-cells: 66.8;Microglia: 35.1;Neutrophils: 19.9;Tuft cells: 69.2" "Cell type enriched" "Detected in some" 7 "central nervous system macrophage: 40.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 11 "memory B-cell: 21.5;naive B-cell: 43.0" "Lineage enriched" "Detected in many" 14 "B-cells: 43.0" "Cancer enriched" "Detected in some" 7 "lymphoma: 15.5" "Lung - B-cells (Lung), Spleen - B-cells (Spleen), Testis - Late spermatids, Thyroid gland - T-cells" "Not detected" "Not detected" NA NA "Cluster 18: Non-specific - Translation" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 25: Non-specific - Transcription" "Cluster 55: Lymphoma - Immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 19 "unprognostic (1.01e-2)" "unprognostic (8.05e-3)" "unprognostic (3.29e-1)" "unprognostic (5.99e-2)" "unprognostic (1.84e-1)" "unprognostic (8.26e-2)" "unprognostic (1.64e-2)" "unprognostic (4.38e-3)" "unprognostic (2.81e-2)" CLEC18A MRCL ENSG00000157322 "C-type lectin domain family 18 member A" A5D8T8 16 69950705-69964452 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "blood vessel: 13.4;choroid plexus: 15.4;kidney: 27.1" "Cell type enhanced" "Detected in some" "Foveolar cells: 2.7;Neutrophils: 7.5;Paneth cells: 3.9;Proximal tubule cells: 12.6;Sertoli cells: 2.8" "Cell type enhanced" "Detected in single" "upper rhombic lip: 1.0" "Cancer enriched" "Detected in some" 10 "Kidney Renal Clear Cell Carcinoma (TCGA): 62.5" "Region enhanced" "Detected in some" "choroid plexus: 6.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "lung cancer: 3.8" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" HPA048976 Uncertain "Secreted to blood" "No annotated function" NA NA 3110000 "Cluster 72: Kidney - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 24: Neutrophils - Innate immunity signal integration" 6 "HPA048976: " "unprognostic (5.07e-2)" "unprognostic (1.56e-3)" "unprognostic (1.81e-2)" "validated prognostic favorable (4.30e-7)" "validated prognostic favorable (6.22e-6)" "unprognostic (1.87e-1)" "unprognostic (1.74e-1)" "unprognostic (2.23e-1)" "unprognostic (8.12e-3)" CLEC18B MRCL2 ENSG00000140839 "C-type lectin domain family 18 member B" Q6UXF7 16 74408631-74421478 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "kidney: 30.0" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 8.3;Esophageal apical cells: 3.5;Proximal tubule cells: 20.2;Retinal ganglion cells: 7.7;Retinal horizontal cells: 4.0;Sertoli cells: 25.9" "Low cell type specificity" "Detected in some" "Group enriched" "Detected in many" 4 "Glioblastoma Multiforme (TCGA): 17.5;Kidney Renal Clear Cell Carcinoma (TCGA): 66.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 3.5" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" HPA048976 Uncertain "Secreted to blood" "No annotated function" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 54: Immune cells - T cell receptor" "Cluster 11: Neuronal - Sensory perception" "Cluster 88: Proximal tubular cells - Transmembrane transport" "HPA048976: " "unprognostic (1.06e-1)" "unprognostic (1.19e-1)" "potential prognostic unfavorable (7.37e-4)" "unprognostic (3.44e-1)" "unprognostic (1.80e-1)" "validated prognostic favorable (8.32e-7)" "validated prognostic favorable (1.24e-4)" "unprognostic (6.47e-2)" "unprognostic (2.02e-1)" "unprognostic (1.73e-1)" "unprognostic (8.64e-2)" "unprognostic (1.11e-1)" CLEC18C "MGC34761, MRCL3" ENSG00000157335 "C-type lectin domain family 18 member C" Q8NCF0 16 70173322-70187361 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "kidney: 15.1" "Cell type enhanced" "Detected in some" "Granulosa cells: 5.7;Podocytes: 2.8;Proximal tubule cells: 30.6;Retinal ganglion cells: 3.9;Sertoli cells: 9.8" "Cell type enhanced" "Detected in single" "astrocyte: 2.0" "Cancer enriched" "Detected in some" 10 "Kidney Renal Clear Cell Carcinoma (TCGA): 36.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 29 "lung cancer: 4.9" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" HPA048976 Uncertain "Secreted to blood" "No annotated function" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 15: Non-specific - Transcription" "Cluster 11: Neuronal - Sensory perception" "Cluster 88: Proximal tubular cells - Transmembrane transport" "HPA048976: " "unprognostic (9.32e-2)" "validated prognostic favorable (2.11e-7)" "validated prognostic favorable (3.71e-5)" "unprognostic (5.14e-2)" CLEC19A ENSG00000261210 "C-type lectin domain containing 19A" Q6UXS0 16 19285731-19322145 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.3" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 15.9;Fallopian tube ciliated cells: 22.3;Foveolar cells: 9.9;Microglia: 28.8;Respiratory ciliated cells: 81.0;Respiratory deuterosomal cells: 10.4" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 35.4;deep-layer intratelencephalic: 10.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells" "Secreted in brain" "No annotated function" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 107: Ciliated cells - Cilia assembly & function" 1 "unprognostic (1.77e-1)" CLEC1A "CLEC-1, CLEC1, MGC34328" ENSG00000150048 "C-type lectin domain family 1 member A" Q8NC01 12 10069554-10111627 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 46.8;placenta: 46.1" "Cell type enhanced" "Detected in some" "cDC: 24.6;Cytotrophoblasts: 69.3;Extravillous trophoblasts: 97.4;Lymphatic endothelial cells: 30.9;Migrating cytotrophoblasts: 76.3;Neutrophils: 24.5;Syncytiotrophoblasts: 58.8;Vascular endothelial cells: 129.7" "Group enriched" "Detected in some" 6 "endothelial cell: 148.0;fibroblast: 81.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.1" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "testis cancer: 5.1" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in some" "Region enhanced" "Detected in many" "spinal cord: 8.4" CAB080705 Approved "Plasma membrane,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 25: Non-specific - Transcription" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 13 "Plasma membrane" Cytosol "CAB080705: " "unprognostic (9.98e-2)" "unprognostic (7.97e-2)" "unprognostic (3.20e-3)" "unprognostic (3.84e-2)" "unprognostic (5.57e-2)" "unprognostic (1.33e-1)" "unprognostic (1.06e-1)" "unprognostic (1.82e-2)" "unprognostic (2.11e-2)" "unprognostic (1.59e-2)" "validated prognostic favorable (4.62e-5)" "validated prognostic favorable (1.20e-4)" "unprognostic (1.36e-1)" "unprognostic (4.04e-3)" "unprognostic (3.59e-2)" "unprognostic (5.43e-2)" "unprognostic (2.97e-1)" "unprognostic (8.26e-2)" "unprognostic (2.18e-1)" "unprognostic (2.43e-2)" "unprognostic (2.03e-2)" "unprognostic (2.07e-2)" "unprognostic (6.92e-2)" "unprognostic (2.70e-2)" "unprognostic (5.48e-2)" "unprognostic (4.84e-3)" "unprognostic (1.68e-1)" "unprognostic (2.21e-1)" "unprognostic (1.73e-2)" CLEC1B "CLEC-2, CLEC2" ENSG00000165682 "C-type lectin domain family 1 member B" Q9P126 12 9985642-10013424 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "liver: 74.8" "Group enriched" "Detected in some" 15 "Megakaryocytes: 432.7;Platelets: 1199.7" "Cell type enhanced" "Detected in single" "leukocyte: 1.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 15.6" "Group enriched" "Detected in many" 4 "granulocytes: 15.6;monocytes: 5.1" "Group enriched" "Detected in some" 24 "Leukemia: 5.3;Myeloma: 4.4;Rhabdoid: 4.0" "Liver - Sinusoid Endothelial cells, Spleen - Neutrophils_2" "Not detected" "Not detected" "Not detected" "Not detected" HPA051108 Approved NA NA 4100 "Cluster 7: Non-specific - Innate immune response" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 47: Platelets - Hemostasis" 2 "HPA051108: " "unprognostic (7.42e-2)" "unprognostic (2.42e-2)" "unprognostic (9.33e-2)" CLEC20A "FLJ44005, LINC00083, NCRNA00083, RP4-593C16.2" ENSG00000188585 "C-type lectin domain containing 20A" Q6ZU45 1 178479240-178499634 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 1.1;testis: 2.9" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 15.8;Brain inhibitory neurons: 15.0;Cardiomyocytes: 27.4;Cone photoreceptor cells: 26.9;Early spermatids: 33.5;Hepatic stellate cells: 25.8;Late spermatids: 14.9;Retinal ganglion cells: 27.0;Retinal horizontal cells: 18.0;Rod photoreceptor cells: 30.7;Syncytiotrophoblasts: 12.3" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "memory B-cell: 3.2;naive B-cell: 10.8" "Lineage enriched" "Detected in many" 6 "B-cells: 10.8" "Not detected" "Not detected" "Testis - Late spermatids" "Low region specificity" "Detected in all" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 6: Leukemia - Signal transduction" "Cluster 98: Neurons - Neurotransmission & signaling" CLEC2A "INPE5792, KACL, PILAR, UNQ5792" ENSG00000188393 "C-type lectin domain family 2 member A" Q6UVW9 12 9898673-9932370 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "skin 1: 54.3" "Group enriched" "Detected in some" 7 "Basal keratinocytes: 26.1;Ocular epithelial cells: 15.7;Suprabasal keratinocytes: 45.5" "Cell type enhanced" "Detected in some" "deep-layer corticothalamic and 6b: 4.4;oligodendrocyte: 4.2" "Cancer enhanced" "Detected in some" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 2.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 16 "Leukemia: 8.3" "Skin - Keratinocyte (other)" "HPA048530, HPA072407" Approved Uncertain "Plasma membrane" NA NA "Cluster 37: Skin - Keratinization" "Cluster 25: Non-specific - Transcription" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 26: Keratinocytes - Keratinization" 5 "Plasma membrane" "HPA048530: , HPA072407: " "unprognostic (2.67e-1)" "unprognostic (3.59e-1)" CLEC2B "AICL, CLECSF2, HP10085" ENSG00000110852 "C-type lectin domain family 2 member B" Q92478 12 9852369-9869386 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 106.6" "Cell type enhanced" "Detected in many" "cDC: 166.3;Conjunctival goblet cells: 327.2;Decidual stromal cells: 176.9;Esophageal basal cells: 225.1;Innate lymphoid cells: 180.9;Kupffer cells: 228.6;Macrophages: 192.1;monocytes: 196.4;Neutrophils: 449.3;NK-cells: 396.8;Ocular epithelial cells: 335.1;T-cells: 343.0;Vascular endothelial cells: 182.6" "Group enriched" "Detected in some" 6 "endothelial cell: 152.7;leukocyte: 238.8" "Cancer enhanced" "Detected in all" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 69.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 222.5" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 37.0" "Pancreas - Endothelial cells" "Low region specificity" "Detected in all" HPA008194 Enhanced "Intracellular and membrane" "No annotated function" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 15: Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 82 "HPA008194: " "unprognostic (2.09e-1)" "unprognostic (2.56e-3)" "unprognostic (1.77e-1)" "unprognostic (3.26e-2)" "unprognostic (5.71e-2)" "unprognostic (2.35e-2)" "unprognostic (1.29e-3)" "unprognostic (1.06e-2)" "unprognostic (2.97e-1)" "unprognostic (8.17e-2)" "potential prognostic unfavorable (4.85e-6)" "unprognostic (2.91e-1)" "unprognostic (1.80e-2)" "unprognostic (2.18e-1)" "unprognostic (5.06e-2)" "unprognostic (6.89e-2)" "unprognostic (3.90e-2)" "unprognostic (3.10e-2)" "unprognostic (2.93e-2)" "unprognostic (2.80e-1)" "unprognostic (1.64e-2)" "unprognostic (1.91e-3)" "unprognostic (1.16e-3)" "unprognostic (1.09e-1)" "unprognostic (1.13e-1)" "unprognostic (9.17e-2)" "unprognostic (7.92e-2)" "unprognostic (2.38e-1)" "unprognostic (9.68e-3)" "unprognostic (1.41e-1)" "unprognostic (1.15e-1)" CLEC2D "CLAX, LLT1, OCIL" ENSG00000069493 "C-type lectin domain family 2 member D" Q9UHP7 12 9664969-9699553 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 50.4" "Cell type enhanced" "Detected in many" "B-cells: 253.8;Microglia: 153.9;NK-cells: 299.0;Sertoli cells: 319.4;T-cells: 493.7;Thymocytes: 165.2" "Group enriched" "Detected in all" 4 "central nervous system macrophage: 218.7;leukocyte: 592.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 10 "gdT-cell: 188.8;MAIT T-cell: 114.9;memory B-cell: 95.7;memory CD4 T-cell: 184.0;memory CD8 T-cell: 208.9;naive B-cell: 128.1;naive CD4 T-cell: 193.2;naive CD8 T-cell: 223.9;T-reg: 175.8" "Group enriched" "Detected in all" 11 "B-cells: 128.1;T-cells: 223.9" "Group enriched" "Detected in many" 6 "Leukemia: 19.5;lymphoma: 70.3;Myeloma: 19.4" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Liver - T-cells, Spleen - B-cells (Spleen), Thyroid gland - T-cells" "HPA017649, HPA047584" Uncertain Uncertain "Golgi apparatus" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 9: T-cells - Adaptive immunity: Regulation" 2 "Golgi apparatus" "HPA017649: , HPA047584: " "unprognostic (4.36e-3)" "unprognostic (3.25e-2)" "unprognostic (2.10e-1)" "potential prognostic favorable (8.47e-4)" "unprognostic (2.74e-2)" "unprognostic (7.62e-3)" "unprognostic (3.30e-1)" "unprognostic (5.31e-3)" "potential prognostic favorable (4.00e-4)" "unprognostic (6.74e-2)" "potential prognostic unfavorable (3.26e-5)" "unprognostic (3.76e-1)" "unprognostic (2.43e-1)" "unprognostic (2.77e-1)" "unprognostic (1.40e-1)" "unprognostic (2.37e-3)" "unprognostic (9.14e-2)" "unprognostic (2.05e-1)" "unprognostic (1.86e-1)" "unprognostic (2.02e-1)" "unprognostic (4.80e-2)" "unprognostic (9.77e-2)" "unprognostic (3.03e-3)" "unprognostic (2.25e-1)" "unprognostic (2.24e-1)" "unprognostic (2.13e-3)" "unprognostic (1.63e-2)" "unprognostic (9.83e-2)" "unprognostic (1.12e-1)" "unprognostic (8.08e-2)" "unprognostic (1.47e-2)" CLEC2L FLJ32986 ENSG00000236279 "C-type lectin domain family 2 member L" P0C7M8 7 139523685-139544985 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 37.9;parathyroid gland: 13.3;retina: 9.5" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 46.8;Brain inhibitory neurons: 54.5;Megakaryocytes: 24.7;Other brain neurons: 54.9;Platelets: 64.6;Retinal amacrine cells: 35.3;Retinal ganglion cells: 146.8" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 6.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 4.4;Myeloma: 5.3" "Colon - Enteric glia cells, Skeletal muscle - Skeletal myocytes, Skin - Hair cortex cells, Skin - Inner root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045050 Enhanced NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 109: Neurons - Neuronal signaling" "HPA045050: " "unprognostic (9.54e-2)" "unprognostic (8.15e-3)" "unprognostic (4.79e-3)" "unprognostic (1.25e-1)" "unprognostic (4.40e-2)" "unprognostic (6.27e-3)" "unprognostic (4.13e-1)" "unprognostic (9.87e-2)" "unprognostic (3.10e-1)" "unprognostic (2.18e-3)" "unprognostic (1.19e-1)" CLEC3A CLECSF1 ENSG00000166509 "C-type lectin domain family 3 member A" O75596 16 78022515-78066761 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 8.8;urinary bladder: 5.4" "Cell type enhanced" "Detected in some" "Epicardial cells: 2.3;Myonuclei: 3.6;Oocytes: 4.6;Podocytes: 9.3;Retinal amacrine cells: 5.6;Smooth muscle cells: 11.9" "Cell type enhanced" "Detected in some" "ependymal cell: 1.6;thalamic excitatory: 3.2" "Cancer enriched" "Detected in some" 126 "Breast Invasive Carcinoma (TCGA): 182.8" "Region enriched" "Detected in some" 5 "midbrain: 8.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 14 "breast cancer: 29.9;cervical cancer: 8.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA051511 Uncertain Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" "No annotated function" NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 8 "Endoplasmic reticulum" "HPA051511: " "unprognostic (2.58e-1)" "potential prognostic unfavorable (6.08e-5)" "unprognostic (1.13e-1)" "unprognostic (7.73e-2)" CLEC3B "TN, TNA" ENSG00000163815 "C-type lectin domain family 3 member B" P05452 3 45001548-45036071 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 460.6" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 10.1;Ependymal cells: 121.1;Epididymal clear cells: 12.2;Fibroblasts: 27.2;Late spermatids: 29.1;Leydig cells: 15.4;Pericytes: 9.8;Vascular endothelial cells: 37.4" "Group enriched" "Detected in all" 5 "endothelial cell: 655.3;ependymal cell: 179.7" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 154.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Sarcoma: 16.1" "Adrenal gland - Fibroblasts, Colon - Fibroblasts, Liver - Vascular endothelial cells, Minor Salivary Gland - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblasts_1, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002582, HPA034794" Approved "Secreted to blood" "No annotated function" NA NA 6540000000 6600000000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 19: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 104: Brain endothelial cells - Blood brain barrier" "CAB002582: , HPA034794: " "unprognostic (2.07e-1)" "unprognostic (2.68e-1)" "unprognostic (1.43e-1)" "potential prognostic favorable (1.99e-5)" "unprognostic (2.93e-1)" "unprognostic (1.83e-1)" "unprognostic (2.38e-1)" "unprognostic (1.30e-2)" "potential prognostic favorable (6.65e-4)" "unprognostic (1.65e-1)" "validated prognostic favorable (1.10e-6)" "validated prognostic favorable (4.56e-4)" "unprognostic (7.16e-3)" "validated prognostic favorable (9.15e-9)" "validated prognostic favorable (9.79e-8)" "unprognostic (2.54e-3)" "unprognostic (7.32e-2)" "unprognostic (3.10e-2)" "unprognostic (8.60e-2)" "unprognostic (1.52e-1)" "unprognostic (1.88e-1)" "potential prognostic favorable (3.31e-4)" "unprognostic (1.13e-2)" "unprognostic (6.66e-2)" "unprognostic (3.92e-1)" "unprognostic (1.89e-1)" "unprognostic (3.04e-1)" "unprognostic (7.46e-3)" "unprognostic (2.33e-1)" "unprognostic (9.72e-2)" "unprognostic (8.00e-2)" CLEC4A "CD367, CLECSF6, DCIR, DDB27, hDCIR" ENSG00000111729 "C-type lectin domain family 4 member A" Q9UMR7 12 8123617-8138607 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.4;lymphoid tissue: 25.3" "Cell type enhanced" "Detected in some" "Astrocytes: 4.4;Bergmann glia: 4.0;cDC: 3.1;Distal convoluted tubule cells: 3.0;Ependymal cells: 3.0;Kupffer cells: 3.1;Macrophages: 3.4;Microglia: 15.1;monocytes: 6.5;Neutrophils: 4.3;Oligodendrocyte progenitor cells: 4.2;Other brain neurons: 2.5;Podocytes: 10.3;Renal connecting tubule cells: 2.8" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 21.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 227.9;classical monocyte: 333.0;intermediate monocyte: 198.7;myeloid DC: 328.2;neutrophil: 300.4;non-classical monocyte: 130.7" "Group enriched" "Detected in all" 13 "dendritic cells: 328.2;granulocytes: 300.4;monocytes: 333.0" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" HPA007842 Uncertain NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 7: Non-specific - Ribosome" "Cluster 59: Leukemia - T-cell receptor" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 37 "HPA007842: " "unprognostic (2.90e-2)" "unprognostic (9.08e-2)" "unprognostic (2.18e-1)" "potential prognostic favorable (6.05e-4)" "unprognostic (2.18e-1)" "unprognostic (9.85e-3)" "unprognostic (1.14e-1)" "unprognostic (4.52e-1)" "unprognostic (3.73e-2)" "unprognostic (1.36e-1)" "unprognostic (2.22e-1)" "unprognostic (2.01e-1)" "unprognostic (4.55e-2)" "unprognostic (1.48e-2)" "unprognostic (2.87e-1)" "potential prognostic favorable (2.05e-4)" "unprognostic (9.66e-2)" "unprognostic (1.70e-2)" "unprognostic (2.39e-1)" "unprognostic (1.89e-1)" "unprognostic (5.76e-1)" "unprognostic (6.08e-2)" "unprognostic (3.40e-2)" "unprognostic (3.14e-1)" "unprognostic (1.11e-2)" "unprognostic (1.67e-2)" "unprognostic (2.51e-2)" "unprognostic (5.37e-2)" "unprognostic (1.48e-2)" "unprognostic (1.32e-1)" "unprognostic (1.29e-1)" CLEC4C "BDCA2, CD303, CLECSF11, CLECSF7, DLEC, HECL" ENSG00000198178 "C-type lectin domain family 4 member C" Q8WTT0 12 7729383-7751605 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 5.1" "Cell type enriched" "Detected in some" 4 "pDCs: 422.8" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Testicular Germ Cell Tumor (TCGA): 1.2" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 16 "plasmacytoid DC: 469.2" "Lineage enriched" "Detected in many" 16 "dendritic cells: 469.2" "Not detected" "Not detected" HPA029432 Approved NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 3 "HPA029432: " "unprognostic (5.88e-3)" "unprognostic (1.61e-1)" "unprognostic (2.40e-1)" "unprognostic (7.59e-2)" CLEC4D "CD368, CLECSF8, Dectin-3, MCL, Mpcl" ENSG00000166527 "C-type lectin domain family 4 member D" Q8WXI8 12 8509475-8522366 "CD markers, Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "bone marrow: 61.1" "Group enriched" "Detected in some" 6 "Neutrophil progenitors: 131.8;Neutrophils: 200.7" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 63 "Testicular Germ Cell Tumor (TCGA): 26.6" "Not detected" "Not detected" "Group enriched" "Detected in many" 17 "classical monocyte: 57.4;neutrophil: 99.4" "Group enriched" "Detected in many" 32 "granulocytes: 99.4;monocytes: 57.4" "Cancer enhanced" "Detected in some" "lymphoma: 3.2;testis cancer: 8.4" "Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophils_2, Pituitary gland - Neutrophils, Spleen - Neutrophils_2, Thyroid gland - Neutrophils" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA004906 Approved NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 15: Bone marrow - Innate immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 54 "HPA004906: " "unprognostic (2.07e-1)" "unprognostic (2.71e-1)" "unprognostic (1.81e-1)" CLEC4E "CLECSF9, MINCLE" ENSG00000166523 "C-type lectin domain family 4 member E" Q9ULY5 12 8533305-8540905 "Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 71.5;lymphoid tissue: 51.1" "Cell type enriched" "Detected in some" 7 "Neutrophils: 1574.6" "Cell type enhanced" "Detected in some" "endothelial cell: 3.2;leukocyte: 3.9" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 20.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 16 "classical monocyte: 129.3;neutrophil: 451.9" "Group enriched" "Detected in many" 17 "granulocytes: 451.9;monocytes: 129.3" "Group enriched" "Detected in some" 8 "Kidney cancer: 30.8;ovarian cancer: 9.6" "Adipose visceral - Neutrophils, Kidney - Macrophages, Liver - Neutrophils, Lung - Neutrophils_2, Pancreas - Macrophages, Prostate - Macrophages, Skin - Macrophages, Spleen - Neutrophils_2, Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA004935 Uncertain NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 9: Non-specific - Receptor signaling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 101 "HPA004935: " "unprognostic (1.36e-1)" "unprognostic (5.81e-2)" "potential prognostic favorable (3.95e-4)" "unprognostic (3.17e-2)" "unprognostic (1.47e-1)" "unprognostic (4.86e-2)" "unprognostic (5.96e-2)" "unprognostic (3.27e-2)" "unprognostic (1.54e-2)" "unprognostic (2.64e-1)" "unprognostic (1.63e-1)" "unprognostic (6.22e-2)" "unprognostic (9.87e-2)" "unprognostic (1.04e-1)" "unprognostic (2.58e-1)" "unprognostic (5.65e-2)" "unprognostic (1.73e-1)" "unprognostic (3.23e-1)" "unprognostic (2.07e-1)" "unprognostic (4.68e-2)" "unprognostic (2.07e-1)" "unprognostic (1.26e-1)" "unprognostic (1.20e-1)" "unprognostic (2.35e-1)" "unprognostic (3.22e-2)" "unprognostic (2.32e-2)" "unprognostic (2.57e-2)" "unprognostic (3.75e-2)" "unprognostic (1.78e-1)" "unprognostic (1.41e-1)" CLEC4F "CLECSF13, FLJ39110, KCLR" ENSG00000152672 "C-type lectin domain family 4 member F" Q8N1N0 2 70808643-70820599 "Predicted membrane proteins" Endocytosis Receptor "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "retina: 16.0" "Cell type enhanced" "Detected in some" "cDC: 22.3;Cone photoreceptor cells: 12.4;Macrophages: 7.1;monocytes: 2.8;Platelets: 2.8;Renal collecting duct intercalated cells: 3.6;Retinal ganglion cells: 7.7;Retinal horizontal cells: 4.0;Rod photoreceptor cells: 16.6" "Cell type enriched" "Detected in single" 10 "leukocyte: 4.1" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "intermediate monocyte: 6.0;non-classical monocyte: 4.4" "Lineage enriched" "Detected in single" 12 "monocytes: 6.0" "Cancer enhanced" "Detected in some" "Bone cancer: 1.5;lymphoma: 3.8" "Breast - T-cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA056101 Approved "Plasma membrane,Cytosol" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 42: Retina - Visual perception" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 82: Dendritic cells - Antigen presentation" "Plasma membrane" Cytosol "HPA056101: " "potential prognostic favorable (2.31e-4)" "potential prognostic favorable (9.56e-4)" CLEC4G "LSECTIN, UNQ431" ENSG00000182566 "C-type lectin domain family 4 member G" Q6UXB4 19 7728957-7733906 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.0;liver: 51.0;lymphoid tissue: 14.5" "Cell type enriched" "Detected in some" 5 "Brain excitatory neurons: 10.4" "Cell type enhanced" "Detected in many" "upper rhombic lip: 16.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "classical monocyte: 18.8;myeloid DC: 15.2" "Group enriched" "Detected in many" 4 "dendritic cells: 15.2;monocytes: 18.8" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Minor Salivary Gland - Macrophages, Skeletal muscle - Macrophages, Thyroid gland - Macrophages" "Not detected" "Not detected" "Not detected" "Not detected" "CAB003789, HPA014044" Enhanced NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 14 "CAB003789: , HPA014044: " "unprognostic (9.38e-2)" "unprognostic (1.82e-3)" "unprognostic (1.10e-1)" "unprognostic (4.79e-2)" "unprognostic (1.13e-1)" CLEC4M "CD209L, CD299, DC-SIGN2, DC-SIGNR, DCSIGNR, HP10347, LSIGN" ENSG00000104938 "C-type lectin domain family 4 member M" Q9H2X3 19 7763210-7769605 "CD markers, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Adaptive immunity, Endocytosis, Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "liver: 58.6;lymphoid tissue: 15.4" "Cell type enhanced" "Detected in some" "Cholangiocytes: 3.9;Decidual stromal cells: 5.4;Granulosa cells: 26.8;Lymphatic endothelial cells: 5.9;Retinal pigment epithelial cells: 4.3;Sertoli cells: 12.8;Vascular endothelial cells: 12.3" "Cell type enhanced" "Detected in some" "cerebellar inhibitory: 1.3;lower rhombic lip: 1.4;thalamic excitatory: 2.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB033689, CAB033691, HPA042661" Supported "Intracellular and membrane" Receptor NA NA 4100000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 45: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 4 "CAB033689: , CAB033691: , HPA042661: " "unprognostic (2.50e-2)" CLEC5A "CLECSF5, MDL-1" ENSG00000258227 "C-type lectin domain containing 5A" Q9NY25 7 141927357-141947007 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "bone marrow: 39.0" "Cell type enhanced" "Detected in some" "cDC: 35.3;Early spermatids: 9.4;Epicardial cells: 11.4;Macrophages: 42.4;Microglia: 8.4;monocytes: 24.1;Neutrophil progenitors: 66.8;Neutrophils: 23.4" "Cell type enriched" "Detected in some" 4 "central nervous system macrophage: 11.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 8 "classical monocyte: 9.1" "Lineage enriched" "Detected in many" 8 "monocytes: 9.1" "Cancer enriched" "Detected in single" 128 "Leukemia: 12.7" "Kidney - Macrophages, Prostate - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054137 Supported "Plasma membrane,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 15: Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 82: Dendritic cells - Antigen presentation" "Plasma membrane, Cytosol" "HPA054137: " "unprognostic (7.73e-2)" "unprognostic (1.68e-2)" "unprognostic (7.06e-2)" "unprognostic (3.89e-2)" "unprognostic (8.70e-2)" "unprognostic (2.08e-1)" "unprognostic (8.42e-3)" "potential prognostic unfavorable (1.43e-4)" "unprognostic (9.22e-2)" "unprognostic (1.83e-1)" "unprognostic (2.86e-2)" "unprognostic (2.99e-3)" "unprognostic (2.06e-2)" "unprognostic (1.03e-1)" "unprognostic (3.94e-3)" "unprognostic (7.88e-2)" "unprognostic (3.77e-2)" "potential prognostic unfavorable (2.59e-4)" "unprognostic (1.19e-2)" "unprognostic (3.53e-3)" "unprognostic (9.39e-2)" "unprognostic (1.14e-3)" "unprognostic (8.90e-2)" "unprognostic (6.49e-2)" "unprognostic (8.09e-3)" "unprognostic (1.55e-1)" "unprognostic (9.16e-2)" "unprognostic (7.67e-2)" CLEC6A "CLECSF10, dectin-2, hDECTIN-2" ENSG00000205846 "C-type lectin domain containing 6A" Q6EIG7 12 8455962-8478330 "Predicted membrane proteins" "Adaptive immunity, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lung: 1.0;lymphoid tissue: 1.1" "Cell type enhanced" "Detected in some" "cDC: 1.5;Epididymal clear cells: 2.0;Monocyte progenitors: 3.4;monocytes: 3.4;Neutrophil progenitors: 2.7;Neutrophils: 3.5;Rod photoreceptor cells: 2.3" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "Testicular Germ Cell Tumor (TCGA): 1.8" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "classical monocyte: 5.4;myeloid DC: 2.2" "Group enriched" "Detected in many" 12 "dendritic cells: 2.2;monocytes: 5.4" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 34: Testis cancer - Unknown function" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" "unprognostic (2.89e-1)" "unprognostic (4.18e-1)" CLEC7A "CD369, CLECSF12, DECTIN-1, hDectin-1, SCARE2" ENSG00000172243 "C-type lectin domain containing 7A" Q9BXN2 12 10116777-10130258 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "bone marrow: 79.1;lung: 27.9;lymphoid tissue: 41.9" "Cell type enhanced" "Detected in many" "cDC: 386.5;Hofbauer cells: 112.8;Kupffer cells: 637.5;Macrophages: 304.9;Microglia: 220.6;monocytes: 474.3;Neutrophils: 663.7;Ocular epithelial cells: 91.6" "Cell type enriched" "Detected in some" 6 "central nervous system macrophage: 297.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 251.5" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in many" 11 "Myeloma: 62.2" "Adipose subcutaneous - Macrophages, Adrenal gland - Macrophages, Colon - Macrophages, Kidney - Macrophages, Pancreas - Macrophages, Skeletal muscle - Macrophages, Skin - T-cells, Spleen - Neutrophils_2, Stomach - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 12 "unprognostic (5.09e-2)" "unprognostic (2.28e-1)" "unprognostic (1.31e-1)" "unprognostic (9.82e-3)" "unprognostic (2.23e-1)" "unprognostic (6.25e-2)" "unprognostic (7.12e-3)" "unprognostic (5.26e-2)" "unprognostic (3.83e-2)" "unprognostic (3.03e-2)" "unprognostic (3.25e-1)" "unprognostic (1.37e-1)" "unprognostic (6.84e-3)" "unprognostic (2.40e-2)" "unprognostic (2.47e-1)" "unprognostic (1.53e-3)" "unprognostic (4.66e-3)" "unprognostic (1.35e-1)" "unprognostic (1.50e-1)" "unprognostic (4.04e-1)" "unprognostic (4.53e-1)" "unprognostic (3.23e-2)" "unprognostic (3.03e-2)" "unprognostic (1.71e-1)" "unprognostic (1.56e-1)" "unprognostic (3.37e-2)" "unprognostic (3.24e-1)" "unprognostic (8.24e-2)" "unprognostic (1.93e-2)" "unprognostic (8.26e-2)" "unprognostic (4.28e-2)" CLEC9A "CD370, DNGR-1, HEEE9341, UNQ9341" ENSG00000197992 "C-type lectin domain containing 9A" Q6UXN8 12 10030678-10066031 "CD markers, Predicted membrane proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.1;lymphoid tissue: 7.0" "Group enriched" "Detected in some" 4 "cDC: 87.9;Hematopoietic stem cells: 50.0;Microglia: 114.4" "Cell type enriched" "Detected in some" 35 "central nervous system macrophage: 137.6" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 4.4" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 96 "myeloid DC: 22.0;neutrophil: 7.9" "Group enriched" "Detected in many" 96 "dendritic cells: 22.0;granulocytes: 7.9" "Group enriched" "Detected in some" 6 "Leukemia: 3.6;Myeloma: 3.2" "Testis - Early spermatids" "Not detected" "Not detected" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 39: Astrocytes - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 82: Dendritic cells - Antigen presentation" "unprognostic (5.34e-2)" "unprognostic (1.38e-2)" "unprognostic (1.49e-1)" "unprognostic (1.50e-3)" "unprognostic (9.52e-3)" "unprognostic (6.07e-2)" CLGN ENSG00000153132 Calmegin O14967 4 140388453-140427661 "Predicted intracellular proteins, Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 55.7;testis: 106.2" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 156.6;Early spermatids: 104.9;Endometrial ciliated cells: 118.7;Fallopian tube ciliated cells: 165.3;Late primary spermatocytes: 756.8;Late spermatids: 70.4;Müller glia: 197.7;Prostatic glandular cells: 141.4" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 31.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "prostate cancer: 40.4" "Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Pituitary gland - Lactotropes, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020709, HPA048761, HPA058627" Enhanced Supported "Endoplasmic reticulum,Equatorial segment,Mid piece" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 35: Non-specific - Mixed function" "Cluster 17: Choroid plexus - Cilium" "Cluster 60: Prostate cancer - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 62 "Endoplasmic reticulum" "Equatorial segment, Mid piece" "CAB020709: , HPA048761: , HPA058627: " "unprognostic (2.26e-2)" "unprognostic (1.71e-1)" "unprognostic (1.83e-2)" "unprognostic (1.38e-1)" "unprognostic (2.08e-1)" "unprognostic (1.73e-2)" "unprognostic (2.90e-1)" "potential prognostic unfavorable (3.55e-5)" "potential prognostic unfavorable (6.53e-6)" "unprognostic (3.52e-3)" "unprognostic (3.77e-2)" "unprognostic (2.32e-3)" "unprognostic (1.04e-2)" "unprognostic (2.24e-2)" "unprognostic (2.83e-1)" "unprognostic (4.28e-2)" "unprognostic (1.76e-1)" "unprognostic (2.82e-1)" "unprognostic (1.08e-1)" "unprognostic (4.27e-3)" "unprognostic (3.92e-2)" "unprognostic (1.09e-2)" "potential prognostic unfavorable (4.80e-4)" "unprognostic (1.32e-1)" "unprognostic (8.92e-2)" CLHC1 "C2orf63, FLJ31438" ENSG00000162994 "Clathrin heavy chain linker domain containing 1" Q8NHS4 2 55172547-55232563 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 190.1;Ependymal cells: 229.8;Respiratory ciliated cells: 138.2" "Cell type enhanced" "Detected in all" "ependymal cell: 257.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA045418, HPA053557" Uncertain Approved "Nucleoli fibrillar center,Centrosome" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 21: Testis - Mixed function" "Cluster 17: Choroid plexus - Cilium" "Cluster 56: Non-specific - Sensory perception" "Cluster 34: Ciliated cells - Cilia assembly & function" 2 "Nucleoli fibrillar center, Centrosome" "HPA045418: , HPA053557: " "unprognostic (1.78e-1)" "unprognostic (6.79e-2)" "unprognostic (3.14e-2)" "unprognostic (1.68e-2)" "unprognostic (8.29e-2)" "unprognostic (5.52e-2)" "unprognostic (4.90e-2)" "unprognostic (3.65e-1)" "unprognostic (4.03e-2)" "potential prognostic unfavorable (6.76e-4)" "unprognostic (1.22e-1)" "unprognostic (3.48e-1)" "unprognostic (8.04e-2)" "unprognostic (1.44e-1)" "unprognostic (6.04e-2)" "unprognostic (2.45e-2)" "unprognostic (1.86e-1)" "unprognostic (3.10e-1)" "unprognostic (1.40e-3)" "unprognostic (1.29e-2)" "unprognostic (1.73e-1)" "unprognostic (5.99e-2)" "unprognostic (7.01e-2)" "unprognostic (3.64e-3)" "unprognostic (2.58e-1)" "unprognostic (4.29e-2)" "unprognostic (3.34e-3)" "unprognostic (2.31e-1)" CLIC1 "CLCNL1, G6, NCC27, p64CLCP" ENSG00000213719 "Chloride intracellular channel 1" O00299 6 31730581-31739763 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Oxidoreductase, Voltage-gated channel" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 179.9;cDC: 131.0;Megakaryocytes: 179.3;Platelets: 313.8;Suprabasal keratinocytes: 201.4" "Group enriched" "Detected in many" 8 "central nervous system macrophage: 27.7;endothelial cell: 84.3;ependymal cell: 29.5;fibroblast: 25.4;leukocyte: 101.2;pericyte: 74.9;vascular associated smooth muscle cell: 65.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020825, CAB040557" Enhanced Supported Cytosol NA NA 40000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 12: Non-specific - Vasculature" "Cluster 28: Non-specific - Nuclear processes" "Cluster 97: Non-specific - Cellular respiration" 16 Cytosol "CAB020825: , CAB040557: " "potential prognostic unfavorable (2.05e-4)" "unprognostic (4.00e-2)" "unprognostic (2.93e-2)" "unprognostic (1.22e-1)" "unprognostic (3.50e-1)" "unprognostic (5.56e-2)" "unprognostic (2.88e-2)" "potential prognostic unfavorable (2.55e-4)" "unprognostic (7.89e-2)" "unprognostic (4.22e-2)" "potential prognostic favorable (6.32e-4)" "unprognostic (4.57e-2)" "unprognostic (1.03e-1)" "validated prognostic unfavorable (2.45e-5)" "validated prognostic unfavorable (9.71e-6)" "potential prognostic unfavorable (8.68e-4)" "unprognostic (1.15e-3)" "unprognostic (1.21e-2)" "unprognostic (2.99e-1)" "unprognostic (9.63e-2)" "unprognostic (1.31e-1)" "potential prognostic unfavorable (7.20e-4)" "unprognostic (4.20e-1)" "unprognostic (8.35e-2)" "potential prognostic favorable (6.27e-4)" "unprognostic (3.52e-1)" "unprognostic (3.17e-1)" "unprognostic (2.85e-1)" "unprognostic (1.29e-1)" "unprognostic (1.77e-1)" "unprognostic (5.44e-2)" CLIC2 "CLCNL2, XAP121" ENSG00000155962 "Chloride intracellular channel 2" O15247 X 155276211-155334657 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Oxidoreductase, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 113.6;Alveolar cells type 2: 143.2;cDC: 196.6;Hematopoietic stem cells: 80.1;Kupffer cells: 210.1;Lymphatic endothelial cells: 110.7;Macrophages: 108.2;Transitional alveolar cells: 67.0;Vascular endothelial cells: 110.1" "Cell type enhanced" "Detected in all" "endothelial cell: 63.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "intermediate monocyte: 18.6;myeloid DC: 48.0;non-classical monocyte: 14.4" "Group enriched" "Detected in many" 16 "dendritic cells: 48.0;monocytes: 18.6" "Cancer enhanced" "Detected in many" "Myeloma: 33.4" "Breast - Endothelial cells, Kidney - Endothelial cells, Pituitary gland - Endothelial cells, Skeletal muscle - Endothelial cells, Spleen - Macrophages" "Low region specificity" "Detected in all" "HPA047381, HPA060101" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 49000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 82: Dendritic cells - Antigen presentation" 2 "Plasma membrane, Cytosol" Nucleoplasm "HPA047381: , HPA060101: " "unprognostic (6.48e-3)" "unprognostic (1.88e-2)" "unprognostic (1.13e-1)" "unprognostic (1.10e-1)" "unprognostic (8.91e-2)" "unprognostic (5.06e-3)" "unprognostic (3.03e-1)" "unprognostic (9.49e-3)" "unprognostic (3.56e-2)" "unprognostic (3.46e-1)" "potential prognostic favorable (7.63e-5)" "unprognostic (5.69e-3)" "potential prognostic unfavorable (2.41e-4)" "unprognostic (2.54e-1)" "unprognostic (1.45e-2)" "unprognostic (2.95e-2)" "unprognostic (3.53e-2)" "unprognostic (1.48e-1)" "unprognostic (2.04e-1)" "unprognostic (4.26e-1)" "unprognostic (6.12e-2)" "unprognostic (2.52e-1)" "unprognostic (4.00e-1)" "unprognostic (2.47e-1)" "unprognostic (1.57e-1)" "unprognostic (4.99e-2)" "unprognostic (1.91e-1)" "unprognostic (8.34e-3)" "unprognostic (4.31e-2)" "unprognostic (9.62e-2)" "unprognostic (8.64e-2)" CLIC3 ENSG00000169583 "Chloride intracellular channel 3" O95833 9 136994608-136996568 "Plasma proteins, Predicted intracellular proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Oxidoreductase, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "cervix: 139.3;esophagus: 434.5;skin 1: 164.4;thyroid gland: 149.0;vagina: 176.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 740.1;Cytotrophoblasts: 812.8;Esophageal apical cells: 8954.1;Esophageal suprabasal cells: 1184.2;Extravillous trophoblasts: 1914.1;Migrating cytotrophoblasts: 1166.3;pDCs: 680.6;Suprabasal keratinocytes: 544.9;Syncytiotrophoblasts: 2612.8" "Cell type enriched" "Detected in some" 4 "leukocyte: 50.5" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 169.6;Thyroid Carcinoma (TCGA): 309.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 9 "plasmacytoid DC: 2643.0" "Lineage enriched" "Detected in all" 9 "dendritic cells: 2643.0" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Liver - NK-cells (Liver), Lung - Alveolar cells type 1, Spleen - NK-cells (Spleen)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA005963 Enhanced Supported "Nuclear bodies" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 25: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." 33 "Nuclear bodies" "HPA005963: " "unprognostic (1.10e-1)" "unprognostic (7.91e-2)" "unprognostic (9.82e-2)" "unprognostic (2.47e-2)" "unprognostic (2.41e-1)" "unprognostic (2.62e-1)" "unprognostic (2.03e-1)" "validated prognostic unfavorable (1.32e-4)" "validated prognostic unfavorable (9.51e-4)" "unprognostic (1.07e-1)" "unprognostic (5.36e-3)" "unprognostic (5.19e-2)" "unprognostic (2.87e-1)" "unprognostic (8.64e-2)" "potential prognostic unfavorable (3.40e-4)" "unprognostic (1.47e-1)" "unprognostic (8.29e-3)" "unprognostic (3.35e-2)" "unprognostic (2.23e-3)" "unprognostic (4.73e-2)" "unprognostic (9.05e-2)" "unprognostic (8.87e-2)" "unprognostic (5.48e-2)" "unprognostic (1.51e-1)" "unprognostic (7.91e-3)" "unprognostic (1.65e-2)" "unprognostic (8.42e-2)" "unprognostic (2.48e-1)" CLIC4 "CLIC4L, DKFZP566G223, H1, huH1, P64H1" ENSG00000169504 "Chloride intracellular channel 4" Q9Y696 1 24745382-24844321 "Predicted intracellular proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Oxidoreductase, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 408.2" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 590.8;Epicardial cells: 755.0;Extravillous trophoblasts: 629.5;Mesothelial cells: 588.3;Plasma cells: 613.3;Schwann cells: 1130.9;Smooth muscle cells: 835.4" "Cell type enhanced" "Detected in all" "endothelial cell: 719.9;oligodendrocyte: 290.2;vascular associated smooth muscle cell: 335.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 13.5;naive B-cell: 11.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Skeletal muscle - Endothelial cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008019, HPA060804" Enhanced Supported "Plasma membrane,Centrosome,Calyx,Connecting piece,Principal piece" NA NA 3800000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 7 "Plasma membrane, Centrosome" "Calyx, Connecting piece, Principal piece" "HPA008019: , HPA060804: " "unprognostic (2.90e-1)" "unprognostic (5.65e-2)" "unprognostic (1.58e-3)" "unprognostic (4.17e-3)" "unprognostic (2.82e-1)" "unprognostic (1.90e-1)" "unprognostic (9.82e-2)" "unprognostic (1.84e-1)" "unprognostic (1.86e-1)" "unprognostic (5.81e-3)" "potential prognostic favorable (2.33e-7)" "unprognostic (2.67e-2)" "potential prognostic favorable (4.05e-4)" "unprognostic (6.48e-3)" "unprognostic (3.78e-2)" "unprognostic (3.03e-2)" "potential prognostic unfavorable (6.26e-4)" "unprognostic (9.51e-3)" "unprognostic (1.82e-1)" "unprognostic (2.03e-3)" "unprognostic (1.65e-2)" "unprognostic (6.28e-3)" "unprognostic (1.09e-1)" "unprognostic (1.11e-1)" "unprognostic (1.25e-1)" "unprognostic (7.53e-2)" "unprognostic (3.16e-2)" "unprognostic (1.50e-3)" "unprognostic (3.98e-1)" "unprognostic (3.13e-3)" "unprognostic (1.43e-1)" CLIC5 DFNB102 ENSG00000112782 "Chloride intracellular channel 5" Q9NZA1 6 45880827-46080348 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Hearing, Ion transport, Sensory transduction, Transport, Vision" "Chloride channel, Ion channel, Oxidoreductase, Voltage-gated channel" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 96.2;skeletal muscle: 271.2;tongue: 91.9" "Group enriched" "Detected in many" 4 "Alveolar cells type 1: 992.7;Podocytes: 3048.4" "Cell type enriched" "Detected in many" 5 "endothelial cell: 204.7" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 26.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 5.1" "Lineage enriched" "Detected in single" 17 "T-cells: 5.1" "Cancer enhanced" "Detected in many" "colorectal cancer: 11.2;ovarian cancer: 13.8" "Breast - Endothelial cells, Heart muscle - Cardiomyocytes, Kidney - Podocytes, Lung - Alveolar cells type 1, Pituitary gland - Undifferentiated cells (Pituitary gland), Skeletal muscle - Skeletal myocytes, Spleen - Fibroblasts_1, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074371 Supported "Nuclear speckles,Plasma membrane" NA NA 750000 "Cluster 1: T-cells - Unknown function" "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 57: Podocytes - Glomerular filtration" 1 "Plasma membrane" "Nuclear speckles" "HPA074371: " "unprognostic (6.11e-3)" "unprognostic (1.04e-1)" "potential prognostic favorable (5.59e-4)" "unprognostic (3.55e-2)" "unprognostic (2.20e-1)" "unprognostic (6.02e-2)" "unprognostic (2.99e-2)" "unprognostic (7.39e-2)" "potential prognostic favorable (8.40e-8)" "unprognostic (2.69e-3)" "unprognostic (2.37e-1)" "unprognostic (1.23e-2)" "unprognostic (1.19e-2)" "unprognostic (9.39e-3)" "unprognostic (4.74e-3)" "unprognostic (3.02e-1)" "unprognostic (1.16e-2)" "unprognostic (3.00e-3)" "unprognostic (1.30e-1)" "unprognostic (2.85e-1)" "unprognostic (1.41e-1)" "unprognostic (2.12e-2)" "unprognostic (1.79e-1)" "unprognostic (1.75e-1)" "unprognostic (2.58e-2)" "unprognostic (2.32e-2)" CLIC6 "CLIC1L, CLIC5" ENSG00000159212 "Chloride intracellular channel 6" Q96NY7 21 34668994-34718227 "Predicted intracellular proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Oxidoreductase, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "choroid plexus: 410.0;stomach 1: 126.7" "Group enriched" "Detected in many" 4 "Choroid plexus epithelial cells: 2259.0;Parietal cells: 1433.8;Retinal pigment epithelial cells: 856.9" "Cell type enriched" "Detected in many" 8 "choroid plexus epithelial cell: 1750.1" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 56.2" "Region enriched" "Detected in all" 21 "choroid plexus: 505.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 4.4;lung cancer: 2.8" "Heart muscle - Cardiomyocytes, Liver - Cholangiocytes, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065285 Enhanced NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 4 "HPA065285: " "unprognostic (1.54e-2)" "potential prognostic favorable (1.10e-4)" "unprognostic (1.83e-1)" "unprognostic (4.75e-2)" "unprognostic (4.32e-2)" "unprognostic (1.18e-1)" "potential prognostic unfavorable (1.20e-4)" "unprognostic (1.84e-2)" "unprognostic (2.38e-2)" "unprognostic (5.81e-2)" "unprognostic (1.46e-2)" "potential prognostic favorable (6.39e-4)" "unprognostic (9.06e-3)" "potential prognostic favorable (4.85e-5)" "unprognostic (1.34e-1)" "unprognostic (4.97e-2)" "unprognostic (1.38e-1)" "unprognostic (3.14e-1)" "unprognostic (7.16e-3)" "unprognostic (9.55e-2)" "unprognostic (2.67e-1)" "unprognostic (3.07e-2)" "unprognostic (2.18e-1)" "unprognostic (2.25e-1)" "unprognostic (2.59e-2)" "unprognostic (1.04e-2)" "unprognostic (2.58e-1)" "unprognostic (1.03e-1)" "unprognostic (1.61e-1)" CLINT1 "CLINT, ENTH, EPNR, KIAA0171" ENSG00000113282 "Clathrin interactor 1" Q14677 5 157785743-157859145 "Plasma proteins, Predicted intracellular proteins, Transporters" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 611.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "basophil: 751.5" "Lineage enriched" "Detected in all" 10 "granulocytes: 751.5" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Lung - Alveolar cells type 2, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043280, HPA056947" Supported Supported Nucleoplasm,Vesicles NA NA 350000 "Cluster 46: Basophils - Proteolysis" "Cluster 76: Non-specific - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 52 Vesicles Nucleoplasm "HPA043280: , HPA056947: " "unprognostic (2.73e-2)" "unprognostic (5.94e-2)" "unprognostic (2.94e-1)" "unprognostic (3.49e-3)" "potential prognostic favorable (3.80e-4)" "unprognostic (1.67e-1)" "unprognostic (2.82e-1)" "unprognostic (1.20e-1)" "unprognostic (2.26e-1)" "unprognostic (8.66e-3)" "potential prognostic favorable (3.76e-9)" "unprognostic (7.39e-3)" "unprognostic (1.83e-1)" "unprognostic (5.53e-2)" "unprognostic (6.86e-2)" "unprognostic (6.98e-2)" "unprognostic (9.32e-2)" "unprognostic (1.94e-1)" "unprognostic (7.00e-2)" "unprognostic (2.03e-1)" "unprognostic (1.79e-1)" "potential prognostic unfavorable (1.26e-4)" "unprognostic (2.52e-1)" "unprognostic (1.52e-1)" "unprognostic (1.02e-3)" "potential prognostic unfavorable (4.22e-4)" "unprognostic (2.28e-1)" "unprognostic (2.50e-1)" "unprognostic (3.01e-1)" "unprognostic (8.87e-3)" "unprognostic (3.72e-1)" CLIP1 "CLIP, CLIP-170, CLIP170, CYLN1, RSN" ENSG00000130779 "CAP-Gly domain containing linker protein 1" P30622 12 122271432-122422669 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 283.5" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1160.0;Myonuclei: 1170.5;Syncytiotrophoblasts: 1160.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004399, HPA026678" Approved Approved "Microtubule ends,Cytosol,Mid piece,Principal piece" NA NA 5000 "Cluster 28: Neutrophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 2: Neurons - Nucleosome" "Cluster 38: Non-specific - Transcription" "Cluster 55: Myocytes - Oxidative muscle function" 70 "Microtubule ends, Mid piece" "Cytosol, Principal piece" "CAB004399: , HPA026678: " "unprognostic (1.48e-1)" "unprognostic (8.55e-3)" "unprognostic (3.68e-1)" "unprognostic (2.96e-2)" "unprognostic (2.33e-1)" "unprognostic (2.41e-3)" "unprognostic (1.58e-1)" "unprognostic (3.02e-2)" "unprognostic (1.11e-1)" "unprognostic (4.15e-2)" "potential prognostic favorable (6.56e-4)" "unprognostic (2.49e-1)" "unprognostic (2.12e-1)" "unprognostic (1.52e-1)" "unprognostic (2.43e-1)" "unprognostic (3.74e-2)" "unprognostic (4.00e-2)" "unprognostic (1.45e-1)" "unprognostic (3.25e-1)" "unprognostic (1.31e-1)" "potential prognostic unfavorable (8.50e-4)" "unprognostic (5.88e-3)" "unprognostic (1.08e-2)" "unprognostic (2.60e-1)" "unprognostic (2.35e-2)" "unprognostic (5.74e-2)" "unprognostic (2.69e-1)" "unprognostic (4.43e-2)" "unprognostic (1.42e-1)" "unprognostic (2.77e-1)" "unprognostic (1.18e-1)" CLIP2 "CLIP, CLIP-115, CYLN2, KIAA0291, WBSCR3, WBSCR4, WSCR3, WSCR4" ENSG00000106665 "CAP-Gly domain containing linker protein 2" Q9UDT6 7 74289407-74405935 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "brain: 78.2" "Cell type enhanced" "Detected in many" "Endometrial luminal cells: 274.6;Oligodendrocytes: 172.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 96.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Spleen - Fibroblasts_1, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020430, CAB020767" Enhanced Approved "Golgi apparatus,Plasma membrane" NA NA 8800 "Cluster 40: Monocytes - Innate immune response" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 6: Non-specific - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 82: Dendritic cells - Antigen presentation" 7 "Golgi apparatus, Plasma membrane" "CAB020767: , HPA020430: " "unprognostic (6.60e-2)" "unprognostic (2.15e-2)" "unprognostic (1.63e-1)" "unprognostic (9.94e-2)" "unprognostic (7.45e-2)" "unprognostic (1.47e-2)" "unprognostic (2.25e-1)" "unprognostic (1.18e-2)" "unprognostic (4.34e-1)" "unprognostic (8.86e-3)" "unprognostic (8.26e-3)" "unprognostic (1.35e-2)" "unprognostic (3.02e-1)" "unprognostic (9.58e-3)" "unprognostic (1.93e-2)" "unprognostic (6.74e-2)" "unprognostic (2.16e-2)" "unprognostic (6.47e-2)" "unprognostic (1.25e-1)" "unprognostic (9.76e-3)" "unprognostic (7.92e-2)" "unprognostic (1.43e-1)" "unprognostic (2.47e-2)" "unprognostic (7.14e-2)" "unprognostic (1.57e-1)" "unprognostic (1.80e-1)" "unprognostic (1.11e-1)" "unprognostic (1.92e-1)" "unprognostic (1.35e-1)" "unprognostic (1.67e-2)" "unprognostic (4.84e-3)" CLIP3 "CLIPR-59, RSNL1" ENSG00000105270 "CAP-Gly domain containing linker protein 3" Q96DZ5 19 36014660-36033343 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 210.5" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 51.8;Brain inhibitory neurons: 57.0;Late spermatids: 38.2;Oligodendrocyte progenitor cells: 38.3;Other brain neurons: 62.4;Retinal amacrine cells: 43.1;Retinal bipolar cells: 31.8;Retinal horizontal cells: 36.1" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 4 "Glioblastoma Multiforme (TCGA): 119.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Neuroblastoma: 48.0" "Liver - Hepatic stellate cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA079430 Uncertain NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 27: Cerebellum - Synaptic function" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 9 "HPA079430: " "unprognostic (4.87e-3)" "unprognostic (5.53e-2)" "unprognostic (4.24e-1)" "unprognostic (1.20e-1)" "unprognostic (1.56e-2)" "unprognostic (3.49e-1)" "unprognostic (1.19e-1)" "unprognostic (2.52e-1)" "unprognostic (2.05e-1)" "unprognostic (4.64e-2)" "unprognostic (3.71e-3)" "unprognostic (2.19e-2)" "unprognostic (5.72e-3)" "unprognostic (4.67e-2)" "unprognostic (5.72e-2)" "unprognostic (2.02e-2)" "unprognostic (3.88e-1)" "unprognostic (1.86e-2)" "unprognostic (3.75e-1)" "unprognostic (5.95e-3)" "unprognostic (3.71e-1)" "unprognostic (1.20e-3)" "unprognostic (1.36e-1)" "unprognostic (1.11e-1)" "unprognostic (8.45e-2)" "unprognostic (2.13e-2)" "unprognostic (1.57e-1)" "unprognostic (1.35e-2)" "unprognostic (3.44e-2)" "unprognostic (1.14e-1)" "unprognostic (2.54e-1)" CLIP4 "FLJ21069, RSNL2" ENSG00000115295 "CAP-Gly domain containing linker protein family member 4" Q8N3C7 2 29097705-29199777 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 284.8;Podocytes: 577.9;Retinal pigment epithelial cells: 336.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 24.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043366, HPA056246" Uncertain Approved Vesicles NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 15 Vesicles "HPA043366: , HPA056246: " "unprognostic (1.35e-1)" "unprognostic (4.52e-2)" "unprognostic (1.07e-1)" "unprognostic (5.83e-3)" "unprognostic (1.78e-2)" "unprognostic (1.91e-1)" "unprognostic (4.05e-1)" "unprognostic (2.81e-1)" "unprognostic (6.53e-2)" "unprognostic (1.22e-2)" "potential prognostic unfavorable (2.69e-4)" "unprognostic (7.78e-3)" "unprognostic (1.39e-3)" "unprognostic (5.98e-3)" "unprognostic (2.15e-1)" "unprognostic (1.23e-2)" "unprognostic (2.60e-1)" "unprognostic (2.20e-1)" "unprognostic (2.82e-2)" "unprognostic (9.64e-3)" "unprognostic (1.59e-2)" "unprognostic (1.11e-1)" "unprognostic (4.10e-3)" "unprognostic (1.87e-1)" "unprognostic (3.16e-3)" "unprognostic (9.37e-2)" "unprognostic (3.75e-1)" "potential prognostic unfavorable (3.20e-4)" "unprognostic (5.32e-2)" "unprognostic (1.21e-1)" "unprognostic (7.70e-2)" CLK1 ENSG00000013441 "CDC like kinase 1" P49759 2 200853009-200864691 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033141, HPA062405" Approved Supported "Nucleoplasm,Nuclear membrane" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 75: Non-specific - Chaperones and protein folding" 20 "Nucleoplasm, Nuclear membrane" "CAB033141: , HPA062405: " "unprognostic (1.57e-1)" "unprognostic (7.28e-2)" "unprognostic (2.69e-1)" "unprognostic (3.33e-2)" "unprognostic (1.49e-2)" "unprognostic (1.85e-2)" "unprognostic (4.00e-1)" "unprognostic (2.64e-2)" "unprognostic (5.12e-2)" "unprognostic (4.80e-3)" "unprognostic (2.06e-1)" "unprognostic (1.63e-2)" "unprognostic (1.37e-2)" "unprognostic (5.72e-2)" "unprognostic (2.13e-1)" "unprognostic (9.68e-2)" "unprognostic (1.38e-1)" "unprognostic (3.17e-1)" "unprognostic (9.02e-2)" "unprognostic (2.40e-1)" "unprognostic (1.27e-1)" "unprognostic (6.91e-2)" "unprognostic (2.68e-3)" "unprognostic (1.28e-1)" "unprognostic (1.45e-1)" "unprognostic (2.84e-3)" "unprognostic (1.57e-1)" "unprognostic (5.79e-3)" "unprognostic (1.80e-1)" "unprognostic (5.95e-2)" "unprognostic (6.64e-2)" CLK2 ENSG00000176444 "CDC like kinase 2" P49760 1 155262868-155278491 "Enzymes, Essential proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 17.9;Bergmann glia: 18.8;Brain excitatory neurons: 12.7;Choroid plexus epithelial cells: 22.4;Distal convoluted tubule cells: 18.3;Loop of henle epithelial cells: 18.4;Microglia: 16.0;Oligodendrocyte progenitor cells: 12.7;Oligodendrocytes: 14.2;Papillary tip epithelial cells: 14.0;Podocytes: 19.1;Proximal tubule cells: 25.4;Renal collecting duct intercalated cells: 17.3;Renal collecting duct principal cells: 17.3;Renal connecting tubule cells: 17.5;Tuft cells: 11.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055366, HPA059507" Approved Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 64: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 102: Non-specific - Mixed function" 102 Nucleoplasm "Nuclear bodies" "HPA055366: , HPA059507: " "unprognostic (2.52e-2)" "unprognostic (3.31e-1)" "unprognostic (1.30e-1)" "unprognostic (1.01e-2)" "unprognostic (7.86e-2)" "unprognostic (7.33e-3)" "unprognostic (1.11e-1)" "unprognostic (3.30e-2)" "unprognostic (5.25e-3)" "unprognostic (8.32e-2)" "potential prognostic unfavorable (2.83e-4)" "unprognostic (2.94e-2)" "unprognostic (5.97e-3)" "unprognostic (7.52e-3)" "unprognostic (1.88e-1)" "unprognostic (2.45e-1)" "unprognostic (3.70e-3)" "unprognostic (1.22e-1)" "unprognostic (4.64e-2)" "unprognostic (1.72e-1)" "unprognostic (1.56e-1)" "unprognostic (1.43e-1)" "unprognostic (3.43e-2)" "unprognostic (1.76e-1)" "unprognostic (7.83e-3)" "unprognostic (8.58e-3)" "unprognostic (1.10e-1)" "unprognostic (2.49e-1)" "unprognostic (1.59e-1)" "unprognostic (5.36e-2)" "unprognostic (5.12e-2)" CLK3 ENSG00000179335 "CDC like kinase 3" P49761 15 74598500-74645414 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 114.1;Esophageal apical cells: 171.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pancreas - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046817 Approved Supported "Nucleoplasm,Intermediate filaments" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 15: Bone marrow - Innate immune response" "Cluster 6: Non-specific - Immune response" "Cluster 58: Non-specific - Nuclear processes" "Cluster 84: Apical squamous epithelium - Cornification" 98 Nucleoplasm "Intermediate filaments" "HPA046817: " "unprognostic (2.08e-1)" "unprognostic (4.66e-2)" "unprognostic (3.44e-1)" "unprognostic (1.46e-2)" "unprognostic (3.33e-2)" "unprognostic (1.25e-1)" "unprognostic (1.47e-1)" "unprognostic (1.55e-2)" "potential prognostic unfavorable (3.43e-5)" "unprognostic (2.01e-1)" "potential prognostic favorable (5.16e-4)" "unprognostic (4.79e-3)" "unprognostic (1.84e-1)" "unprognostic (2.23e-2)" "unprognostic (1.42e-2)" "unprognostic (5.75e-2)" "unprognostic (4.01e-2)" "unprognostic (2.27e-2)" "unprognostic (3.11e-1)" "unprognostic (6.58e-2)" "unprognostic (3.64e-2)" "unprognostic (4.84e-2)" "unprognostic (4.73e-1)" "unprognostic (2.95e-2)" "unprognostic (2.30e-2)" "unprognostic (2.16e-2)" "unprognostic (4.68e-2)" "unprognostic (1.84e-2)" "unprognostic (5.11e-1)" "potential prognostic unfavorable (9.71e-4)" "unprognostic (1.42e-1)" CLK4 ENSG00000113240 "CDC like kinase 4" Q9HAZ1 5 178602664-178630615 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 355.3;Late spermatids: 773.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043746 Approved Approved "Actin filaments" No No "Cluster 24: Non-specific - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 11 "Actin filaments" "HPA043746: " "unprognostic (2.70e-2)" "unprognostic (3.33e-1)" "unprognostic (1.74e-1)" "unprognostic (6.55e-2)" "unprognostic (1.73e-1)" "unprognostic (5.73e-2)" "unprognostic (1.39e-1)" "unprognostic (3.85e-2)" "unprognostic (4.63e-1)" "unprognostic (1.92e-1)" "unprognostic (1.94e-3)" "potential prognostic favorable (9.38e-4)" "unprognostic (8.53e-2)" "unprognostic (6.18e-2)" "unprognostic (4.85e-2)" "unprognostic (1.82e-1)" "unprognostic (2.65e-1)" "unprognostic (1.99e-2)" "unprognostic (3.87e-2)" "unprognostic (8.36e-2)" "unprognostic (8.70e-2)" "unprognostic (3.82e-2)" "unprognostic (1.02e-3)" "unprognostic (3.21e-2)" "unprognostic (1.27e-1)" "unprognostic (3.17e-2)" "unprognostic (1.31e-1)" "unprognostic (7.70e-2)" "unprognostic (2.54e-1)" "unprognostic (2.24e-2)" "unprognostic (1.29e-1)" CLMN "FLJ12383, KIAA0500, KIAA1188" ENSG00000165959 Calmin Q96JQ2 14 95181940-95319908 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 30.5" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 540.4;Late spermatids: 515.6;Oligodendrocytes: 640.6;Pericytes: 408.8;Renal connecting tubule cells: 405.6;Vascular smooth muscle cells: 493.0" "Cell type enhanced" "Detected in all" "oligodendrocyte: 732.2;pericyte: 600.1;vascular associated smooth muscle cell: 598.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012634 Enhanced Approved "Nuclear bodies,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 21: Testis - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 110: Mural cells - ECM organization" 11 "Nuclear bodies" Cytosol "HPA012634: " "unprognostic (1.71e-1)" "unprognostic (3.20e-1)" "unprognostic (3.53e-1)" "unprognostic (1.53e-1)" "unprognostic (2.65e-2)" "unprognostic (2.26e-1)" "unprognostic (2.93e-1)" "unprognostic (4.03e-2)" "unprognostic (1.82e-1)" "unprognostic (6.42e-2)" "validated prognostic favorable (1.95e-7)" "validated prognostic favorable (1.09e-5)" "unprognostic (2.37e-2)" "unprognostic (2.68e-1)" "unprognostic (1.95e-3)" "unprognostic (6.26e-2)" "unprognostic (1.12e-1)" "unprognostic (4.54e-3)" "unprognostic (2.87e-1)" "unprognostic (2.44e-2)" "unprognostic (2.51e-2)" "potential prognostic unfavorable (8.52e-5)" "unprognostic (2.20e-2)" "unprognostic (7.79e-2)" "unprognostic (2.87e-2)" "potential prognostic unfavorable (6.69e-4)" "unprognostic (1.46e-1)" "unprognostic (1.91e-1)" "unprognostic (1.52e-1)" "unprognostic (7.44e-3)" "unprognostic (1.64e-1)" CLMP "ACAM, ASAM, FLJ22415" ENSG00000166250 "CXADR like membrane protein" Q9H6B4 11 123069872-123195248 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 59.3" "Cell type enhanced" "Detected in many" "Adipocytes: 524.2;Adrenal cortex cells: 103.9;Decidual stromal cells: 168.8;Endometrial stromal cells: 247.7;Fibro-adipogenic progenitors: 230.6;Fibroblasts: 235.1;Myosatellite cells: 234.0;Ovarian stromal cells: 105.4;Peritubular myoid cells: 161.2;Retinal amacrine cells: 140.5;Salivary myoepithelial cells: 94.7" "Cell type enhanced" "Detected in all" "cerebellar inhibitory: 533.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 47.4" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 2800000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 35: Non-specific - DNA binding" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 103: Non-specific - Basic cellular processes" 1 "unprognostic (2.54e-1)" "unprognostic (2.15e-2)" "potential prognostic unfavorable (5.38e-4)" "unprognostic (7.53e-2)" "unprognostic (1.22e-1)" "unprognostic (2.38e-3)" "unprognostic (9.01e-2)" "unprognostic (2.02e-2)" "unprognostic (3.38e-3)" "validated prognostic unfavorable (1.14e-8)" "validated prognostic unfavorable (1.99e-6)" "unprognostic (9.96e-2)" "potential prognostic unfavorable (4.49e-4)" "unprognostic (2.00e-1)" "unprognostic (2.24e-2)" "unprognostic (1.78e-1)" "unprognostic (2.79e-3)" "unprognostic (1.01e-3)" "unprognostic (7.22e-3)" "unprognostic (2.46e-1)" "unprognostic (1.01e-1)" "unprognostic (3.11e-2)" "unprognostic (2.95e-2)" "unprognostic (6.03e-2)" "unprognostic (1.65e-3)" "unprognostic (1.10e-1)" "unprognostic (4.83e-3)" "unprognostic (6.62e-2)" CLN3 "BTN1, BTS, JNCL" ENSG00000188603 "CLN3 lysosomal/endosomal transmembrane protein, battenin" Q13286 16 28474111-28495575 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 13.0;Bergmann glia: 12.6;Brain excitatory neurons: 10.3;Brain inhibitory neurons: 10.0;Breast lactating cells: 9.0;Choroid plexus epithelial cells: 13.5;Ependymal cells: 8.4;Microglia: 21.3;Neutrophils: 16.6;NK-cells: 7.5;Oligodendrocyte progenitor cells: 13.4;Oligodendrocytes: 16.1;Other brain neurons: 11.2;Renal collecting duct principal cells: 9.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063280 Uncertain NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 60: Stomach - Digestion" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 27: Breast cancer - Unknown function" "Cluster 22: Non-specific - Basic cellular functions" 22 "HPA063280: " "unprognostic (9.58e-2)" "potential prognostic unfavorable (7.19e-5)" "unprognostic (2.77e-3)" "unprognostic (8.94e-2)" "unprognostic (1.13e-1)" "potential prognostic favorable (1.59e-4)" "unprognostic (1.67e-1)" "unprognostic (2.48e-2)" "unprognostic (7.66e-2)" "unprognostic (3.59e-1)" "potential prognostic favorable (8.88e-8)" "unprognostic (1.81e-1)" "unprognostic (1.05e-2)" "unprognostic (5.23e-3)" "unprognostic (3.38e-3)" "unprognostic (1.62e-1)" "unprognostic (2.41e-1)" "unprognostic (7.42e-2)" "unprognostic (3.56e-1)" "unprognostic (1.66e-1)" "unprognostic (3.36e-1)" "unprognostic (1.39e-1)" "unprognostic (1.67e-1)" "unprognostic (1.68e-1)" "unprognostic (4.74e-2)" "unprognostic (1.61e-3)" "unprognostic (6.32e-2)" "unprognostic (3.62e-1)" "unprognostic (8.79e-2)" "unprognostic (4.77e-2)" "unprognostic (2.60e-1)" CLN5 ENSG00000102805 "CLN5 intracellular trafficking protein" O75503 13 76990660-77019143 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Hydrolase, Transferase" "Disease variant, Epilepsy, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Bergmann glia: 5.2;Conjunctival goblet cells: 4.9;Microglia: 6.1;Oligodendrocyte progenitor cells: 3.8;Oligodendrocytes: 5.0;Respiratory ionocytes: 5.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041788 Approved NA NA 660000 "Cluster 25: Non-specific - Unknown function" "Cluster 72: Kidney - Transmembrane transport" "Cluster 9: Non-specific - Receptor signaling" "Cluster 19: Non-specific - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" 9 "HPA041788: " "unprognostic (3.18e-2)" "unprognostic (7.11e-2)" "unprognostic (4.29e-1)" "unprognostic (1.65e-1)" "unprognostic (8.94e-2)" "unprognostic (9.02e-3)" "unprognostic (3.21e-2)" "unprognostic (1.04e-3)" "unprognostic (5.99e-3)" "unprognostic (3.35e-1)" "potential prognostic favorable (7.38e-9)" "unprognostic (9.05e-3)" "unprognostic (1.45e-2)" "unprognostic (5.46e-2)" "unprognostic (2.56e-2)" "unprognostic (1.13e-1)" "unprognostic (2.31e-1)" "unprognostic (8.60e-2)" "unprognostic (3.12e-1)" "unprognostic (1.76e-1)" "unprognostic (1.32e-2)" "unprognostic (1.28e-1)" "unprognostic (1.10e-1)" "unprognostic (1.32e-1)" "unprognostic (1.58e-2)" "unprognostic (1.75e-1)" "unprognostic (1.45e-1)" "unprognostic (2.18e-1)" "unprognostic (7.89e-2)" "unprognostic (1.34e-1)" "unprognostic (9.11e-2)" CLN6 "FLJ20561, HsT18960, nclf" ENSG00000128973 "CLN6 transmembrane ER protein" Q9NWW5 15 68206992-68257211 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gonadotrophs: 7.5;Medullary thymic epithelial cells: 12.0;Retinal bipolar cells: 7.8;Retinal ganglion cells: 7.7;Thymic myoid cells: 8.2;Thyrotrophs: 8.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Lung - Macrophages, Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066046, HPA066759" Approved Approved "Nucleoli,Endoplasmic reticulum,Vesicles" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 49: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 80: Oligodendrocytes - Myelination" 36 "Endoplasmic reticulum" "Nucleoli, Vesicles" "HPA066046: , HPA066759: " "unprognostic (9.84e-2)" "unprognostic (2.33e-1)" "unprognostic (1.96e-1)" "unprognostic (4.04e-1)" "unprognostic (7.20e-2)" "unprognostic (1.21e-1)" "unprognostic (3.74e-2)" "unprognostic (4.30e-2)" "unprognostic (1.96e-1)" "unprognostic (9.82e-2)" "potential prognostic favorable (3.54e-7)" "unprognostic (2.42e-2)" "potential prognostic favorable (1.45e-4)" "unprognostic (1.86e-2)" "potential prognostic unfavorable (1.86e-6)" "unprognostic (2.52e-3)" "unprognostic (3.88e-2)" "unprognostic (3.50e-1)" "unprognostic (2.56e-1)" "unprognostic (1.19e-1)" "unprognostic (5.99e-3)" "unprognostic (4.68e-2)" "unprognostic (2.47e-1)" "unprognostic (8.65e-3)" "unprognostic (1.30e-1)" "unprognostic (2.62e-1)" "unprognostic (3.77e-2)" "unprognostic (6.07e-2)" "unprognostic (2.90e-1)" "unprognostic (2.10e-1)" "unprognostic (7.65e-2)" CLN8 "C8orf61, EPMR, FLJ39417, TLCD6" ENSG00000182372 "CLN8 transmembrane ER and ERGIC protein" Q9UBY8 8 1755778-1801711 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Epilepsy, Intellectual disability, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 2.0;Choroid plexus epithelial cells: 1.1;Gastric chief cells: 1.1;Kupffer cells: 1.0;Microglia: 4.1" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 5.4;fibroblast: 4.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "plasmacytoid DC: 76.7" "Lineage enriched" "Detected in all" 5 "dendritic cells: 76.7" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 47: Leukemia - Hemostasis" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 1 "unprognostic (1.30e-1)" "unprognostic (1.17e-2)" "potential prognostic favorable (2.49e-4)" "unprognostic (1.96e-1)" "unprognostic (1.04e-1)" "unprognostic (2.71e-3)" "unprognostic (4.88e-3)" "unprognostic (3.01e-2)" "unprognostic (5.00e-2)" "unprognostic (1.86e-2)" "potential prognostic favorable (2.39e-6)" "unprognostic (2.43e-2)" "unprognostic (7.22e-2)" "unprognostic (2.34e-1)" "unprognostic (2.19e-3)" "unprognostic (1.20e-1)" "unprognostic (1.83e-1)" "unprognostic (5.77e-2)" "unprognostic (1.63e-1)" "unprognostic (1.52e-1)" "unprognostic (5.13e-2)" "unprognostic (2.69e-1)" "potential prognostic unfavorable (4.05e-4)" "unprognostic (5.29e-2)" "unprognostic (1.82e-1)" "potential prognostic favorable (1.48e-4)" "unprognostic (2.55e-1)" "unprognostic (3.16e-1)" "unprognostic (1.88e-1)" "unprognostic (2.45e-2)" "unprognostic (2.15e-1)" CLNK MIST ENSG00000109684 "Cytokine dependent hematopoietic cell linker" Q7Z7G1 4 10486395-10684768 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 6.1;lymphoid tissue: 2.5" "Cell type enhanced" "Detected in many" "cDC: 312.8;Epididymal clear cells: 485.8;Renal collecting duct intercalated cells: 2616.1;Respiratory ionocytes: 1051.6;Salivary ionocytes: 879.7;Somatotrophs: 625.7;Thymocytes: 211.7" "Cell type enhanced" "Detected in many" "leukocyte: 15.9" "Cancer enriched" "Detected in some" 23 "Kidney Chromophobe (TCGA): 63.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "thyroid cancer: 3.4" "Kidney - Intercalated cells, Minor Salivary Gland - Minor salivary gland ductal cells, Spleen - B-cells (Spleen), Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035671, HPA035672" Uncertain Uncertain Vesicles NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 72: Kidney - Transmembrane transport" "Cluster 48: Non-specific - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 9 Vesicles "HPA035671: , HPA035672: " "unprognostic (2.37e-1)" "unprognostic (3.02e-2)" "potential prognostic unfavorable (8.95e-4)" "unprognostic (1.65e-1)" "unprognostic (1.05e-1)" "unprognostic (5.51e-2)" "unprognostic (3.20e-1)" "unprognostic (1.02e-3)" "unprognostic (5.11e-2)" CLNS1A "CLCI, ICln" ENSG00000074201 "Chloride nucleotide-sensitive channel 1A" P54105 11 77514936-77637794 "Essential proteins, Predicted intracellular proteins, Transporters" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017840, HPA031707, HPA031708, HPA032045" Approved Supported "Nucleoplasm,Microtubules,Primary cilium,Cytosol,Connecting piece,Mid piece,Principal piece" No No 17000 "Cluster 13: Non-specific - Mitochondria" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 15: Non-specific - Protein processing" 119 "Nucleoplasm, Cytosol" "Microtubules, Primary cilium, Connecting piece, Mid piece, Principal piece" "CAB017840: , HPA031707: , HPA031708: , HPA032045: " "unprognostic (8.18e-2)" "unprognostic (2.32e-1)" "unprognostic (1.25e-1)" "unprognostic (7.30e-2)" "unprognostic (1.00e-1)" "unprognostic (6.33e-2)" "unprognostic (3.44e-3)" "unprognostic (1.55e-2)" "unprognostic (1.86e-2)" "unprognostic (1.01e-2)" "potential prognostic favorable (7.03e-5)" "unprognostic (1.06e-1)" "unprognostic (1.47e-2)" "unprognostic (1.28e-2)" "unprognostic (8.27e-3)" "unprognostic (2.46e-2)" "potential prognostic unfavorable (2.79e-4)" "unprognostic (3.19e-1)" "unprognostic (4.69e-1)" "unprognostic (7.61e-2)" "unprognostic (4.55e-2)" "potential prognostic unfavorable (6.04e-5)" "unprognostic (6.95e-2)" "unprognostic (3.71e-2)" "unprognostic (3.60e-3)" "unprognostic (9.92e-2)" "unprognostic (3.16e-2)" "unprognostic (1.29e-1)" "unprognostic (1.73e-1)" "unprognostic (1.38e-1)" "unprognostic (1.86e-1)" CLOCK "bHLHe8, KAT13D, KIAA0334" ENSG00000134852 "Clock circadian regulator" O15516 4 55427903-55546909 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, DNA damage, Transcription, Transcription regulation" "Activator, Acyltransferase, DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epicardial cells: 514.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001867, HPA027565" Supported Supported Nucleoplasm,Vesicles NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 42: Retina - Visual perception" "Cluster 31: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 29 Nucleoplasm Vesicles "HPA001867: , HPA027565: " "unprognostic (1.95e-2)" "unprognostic (5.20e-3)" "unprognostic (3.44e-1)" "unprognostic (8.59e-3)" "unprognostic (9.50e-3)" "unprognostic (6.23e-2)" "unprognostic (7.27e-2)" "unprognostic (1.21e-1)" "unprognostic (1.43e-2)" "unprognostic (6.90e-3)" "validated prognostic favorable (2.78e-5)" "validated prognostic favorable (7.45e-5)" "unprognostic (4.52e-2)" "unprognostic (5.03e-2)" "unprognostic (3.32e-1)" "unprognostic (8.19e-2)" "unprognostic (4.30e-3)" "unprognostic (4.18e-2)" "unprognostic (1.04e-1)" "unprognostic (2.73e-1)" "unprognostic (7.50e-2)" "unprognostic (5.42e-2)" "unprognostic (4.87e-2)" "unprognostic (1.86e-1)" "unprognostic (3.56e-2)" "unprognostic (6.09e-2)" "unprognostic (2.98e-2)" "unprognostic (6.01e-2)" "unprognostic (2.84e-1)" "unprognostic (4.72e-2)" "unprognostic (1.61e-1)" CLP1 "hClp1, HEAB" ENSG00000172409 "Cleavage factor polyribonucleotide kinase subunit 1" Q92989 11 57648188-57661865 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "mRNA processing, tRNA processing" "Kinase, Transferase" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 47.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Macrophages, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057770 Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 15: Bone marrow - Innate immune response" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 24: Non-specific - Unknown function" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 20 Nucleoplasm Cytosol "HPA057770: " "unprognostic (1.37e-1)" "unprognostic (2.00e-1)" "unprognostic (3.44e-2)" "unprognostic (1.39e-1)" "unprognostic (3.09e-1)" "unprognostic (1.98e-2)" "unprognostic (8.88e-2)" "unprognostic (1.10e-2)" "unprognostic (2.33e-1)" "potential prognostic unfavorable (6.15e-4)" "potential prognostic favorable (4.52e-6)" "unprognostic (2.31e-2)" "unprognostic (2.82e-1)" "unprognostic (1.03e-2)" "unprognostic (9.22e-3)" "unprognostic (4.54e-2)" "unprognostic (1.06e-2)" "unprognostic (1.56e-1)" "unprognostic (4.09e-1)" "unprognostic (2.49e-1)" "unprognostic (9.14e-3)" "unprognostic (1.20e-1)" "unprognostic (1.08e-1)" "unprognostic (1.60e-1)" "potential prognostic favorable (3.67e-4)" "unprognostic (2.13e-2)" "unprognostic (5.66e-2)" "unprognostic (1.04e-1)" "unprognostic (2.64e-1)" "unprognostic (1.60e-1)" "unprognostic (4.86e-2)" CLPB "ANKCLB, FLJ13152, HSP78, SKD3" ENSG00000162129 "Caseinolytic mitochondrial matrix peptidase chaperone subunit B" Q9H078 11 72285495-72434680 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Cataract, Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 12 "testis: 120.0" "Cell type enriched" "Detected in many" 7 "Late spermatids: 9190.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 25.2" "Group enriched" "Detected in all" 5 "dendritic cells: 25.2;granulocytes: 7.7;monocytes: 15.5" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039005, HPA039006, HPA064571" Enhanced NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 23: Testis - Spermatogenesis" "Cluster 45: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 28 "HPA039005: , HPA039006: , HPA064571: " "unprognostic (3.43e-1)" "unprognostic (1.24e-1)" "unprognostic (2.45e-1)" "unprognostic (1.29e-2)" "unprognostic (1.27e-2)" "unprognostic (1.87e-1)" "unprognostic (4.43e-2)" "unprognostic (2.73e-3)" "unprognostic (6.43e-2)" "unprognostic (4.61e-3)" "potential prognostic favorable (1.45e-6)" "unprognostic (3.88e-1)" "unprognostic (9.10e-2)" "unprognostic (4.95e-2)" "unprognostic (2.50e-1)" "unprognostic (2.34e-2)" "unprognostic (1.54e-2)" "unprognostic (9.29e-2)" "unprognostic (1.02e-1)" "unprognostic (5.03e-2)" "unprognostic (1.44e-1)" "unprognostic (3.94e-2)" "unprognostic (1.91e-1)" "unprognostic (2.63e-1)" "unprognostic (1.15e-1)" "unprognostic (6.10e-3)" "unprognostic (8.82e-2)" "unprognostic (1.70e-1)" "unprognostic (2.98e-1)" "unprognostic (3.04e-2)" "unprognostic (1.29e-1)" CLPP ENSG00000125656 "Caseinolytic mitochondrial matrix peptidase proteolytic subunit" Q16740 19 6361531-6370242 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 214.8;Esophageal suprabasal cells: 169.9;Late spermatids: 313.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010649 Supported Supported Mitochondria NA NA 5700 "Cluster 33: Non-specific - ATP binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 237 Mitochondria "HPA010649: " "unprognostic (8.15e-3)" "unprognostic (3.92e-2)" "unprognostic (2.79e-2)" "unprognostic (9.90e-2)" "unprognostic (1.69e-2)" "unprognostic (5.73e-2)" "unprognostic (7.90e-2)" "unprognostic (5.59e-1)" "unprognostic (9.55e-3)" "unprognostic (2.71e-2)" "potential prognostic favorable (6.03e-5)" "unprognostic (3.49e-2)" "unprognostic (2.74e-3)" "unprognostic (5.79e-3)" "unprognostic (1.28e-2)" "unprognostic (3.08e-2)" "unprognostic (5.81e-2)" "unprognostic (2.19e-2)" "unprognostic (2.54e-1)" "unprognostic (3.08e-1)" "unprognostic (1.92e-1)" "unprognostic (2.73e-2)" "unprognostic (2.96e-1)" "unprognostic (7.90e-2)" "unprognostic (6.70e-2)" "unprognostic (6.46e-2)" "unprognostic (6.35e-2)" "unprognostic (6.56e-2)" "unprognostic (6.47e-2)" "unprognostic (1.56e-1)" "unprognostic (7.39e-3)" CLPS ENSG00000137392 Colipase P04118 6 35794982-35797344 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Digestion, Lipid degradation, Lipid metabolism" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 3987 "pancreas: 246873.6" "Cell type enriched" "Detected in some" 721 "Pancreatic acinar cells: 123992.8" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 194 "Pancreatic Adenocarcinoma (TCGA): 3026.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 9 "breast cancer: 2.1" "Pancreas - Exocrine glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA010512 Enhanced "Secreted to digestive system" Other NA NA 480000 "Cluster 8: Pancreas - Proteolysis" "Cluster 51: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 5: Pancreatic acinar cells - Pancreatic exocrine secretion" "HPA010512: " "unprognostic (1.61e-1)" "unprognostic (1.25e-2)" "unprognostic (4.04e-1)" "unprognostic (4.21e-1)" "unprognostic (6.61e-2)" "unprognostic (2.64e-1)" "unprognostic (4.27e-2)" "unprognostic (7.85e-3)" "unprognostic (4.96e-2)" "unprognostic (4.56e-2)" "unprognostic (1.90e-1)" CLPSL1 "C6orf127, dJ510O8.6" ENSG00000204140 "Colipase like 1" A2RUU4 6 35781019-35793675 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 91 "epididymis: 572.6;pancreas: 165.3" "Group enriched" "Detected in some" 46 "Epididymal principal cells: 1181.2;Pancreatic acinar cells: 347.3" "Group enriched" "Detected in some" 4 "deep-layer corticothalamic and 6b: 13.6;deep-layer intratelencephalic: 3.5;hippocampal CA1-3: 9.4;miscellaneous: 4.3" "Cancer enriched" "Detected in many" 9 "Uterine Corpus Endometrial Carcinoma (TCGA): 122.1" "Group enriched" "Detected in some" 4 "basal ganglia: 1.8;cerebral cortex: 5.5;hippocampal formation: 4.0;white matter: 1.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "breast cancer: 8.1" "Breast - Breast glandular cells" HPA073155 Enhanced "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 51: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" "HPA073155: " "unprognostic (2.57e-1)" "unprognostic (4.97e-2)" "unprognostic (8.24e-2)" "unprognostic (6.67e-3)" "unprognostic (4.26e-1)" "unprognostic (3.31e-3)" "unprognostic (5.94e-2)" "unprognostic (1.78e-1)" "unprognostic (7.85e-2)" "unprognostic (4.86e-1)" "unprognostic (2.14e-1)" "unprognostic (4.20e-2)" "unprognostic (2.78e-2)" CLPSL2 "C6orf126, dJ510O8.5, UNQ3045" ENSG00000196748 "Colipase like 2" Q6UWE3 6 35776594-35779552 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 96 "epididymis: 501.4" "Cell type enriched" "Detected in some" 90 "Epididymal principal cells: 2400.8" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Breast Invasive Carcinoma (TCGA): 7.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "breast cancer: 1.7" "Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Skin - Sebaceous gland cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043460, HPA051655" Approved Approved Vesicles "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 27: Breast cancer - Unknown function" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 1 Vesicles "HPA043460: , HPA051655: " "unprognostic (5.44e-2)" "unprognostic (5.61e-2)" "unprognostic (2.76e-2)" "unprognostic (5.20e-1)" CLPTM1 ENSG00000104853 "CLPTM1 regulator of GABA type A receptor forward trafficking" O96005 19 44954585-44993341 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Differentiation "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068767 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 4: Non-specific - Transcription" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 35 "Endoplasmic reticulum" "HPA068767: " "unprognostic (2.93e-1)" "unprognostic (2.85e-2)" "unprognostic (8.39e-2)" "unprognostic (1.45e-2)" "unprognostic (1.83e-1)" "unprognostic (2.62e-3)" "unprognostic (1.92e-1)" "unprognostic (3.56e-2)" "unprognostic (2.16e-1)" "unprognostic (2.26e-1)" "unprognostic (4.39e-1)" "unprognostic (1.07e-1)" "unprognostic (5.64e-2)" "unprognostic (2.98e-3)" "unprognostic (1.85e-1)" "unprognostic (2.21e-3)" "unprognostic (1.49e-1)" "unprognostic (8.12e-2)" "unprognostic (2.41e-1)" "unprognostic (9.50e-3)" "unprognostic (3.41e-1)" "potential prognostic favorable (7.95e-4)" "unprognostic (4.45e-2)" "unprognostic (3.35e-1)" "unprognostic (3.25e-2)" "unprognostic (8.32e-2)" "unprognostic (5.63e-3)" "unprognostic (1.20e-1)" "unprognostic (1.29e-1)" "unprognostic (1.76e-2)" "unprognostic (1.98e-1)" CLPTM1L "CRR9, FLJ14400" ENSG00000049656 "CLPTM1 like" Q96KA5 5 1317752-1345099 "Predicted membrane proteins, Transporters" "Apoptosis, Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 222.0;Plasma cells: 267.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014791 Approved Supported "Endoplasmic reticulum" NA NA 5000 "Cluster 29: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 29: Non-specific - Unknown function" "Cluster 44: Plasma cells - Antibody production & secretion" 6 "Endoplasmic reticulum" "HPA014791: " "unprognostic (1.12e-2)" "unprognostic (5.63e-3)" "unprognostic (1.98e-2)" "unprognostic (2.91e-1)" "unprognostic (3.42e-2)" "unprognostic (2.41e-1)" "unprognostic (8.48e-3)" "unprognostic (8.59e-2)" "unprognostic (3.27e-2)" "potential prognostic unfavorable (1.73e-5)" "potential prognostic favorable (1.37e-5)" "unprognostic (3.31e-1)" "unprognostic (2.25e-3)" "validated prognostic unfavorable (7.77e-5)" "validated prognostic unfavorable (7.01e-4)" "unprognostic (8.02e-2)" "unprognostic (7.13e-2)" "unprognostic (1.96e-1)" "unprognostic (5.98e-2)" "unprognostic (1.49e-2)" "unprognostic (1.31e-2)" "unprognostic (8.86e-3)" "unprognostic (1.21e-2)" "unprognostic (2.03e-1)" "unprognostic (1.52e-1)" "unprognostic (2.13e-1)" "unprognostic (2.00e-1)" "unprognostic (1.50e-1)" "unprognostic (1.89e-1)" "unprognostic (3.59e-3)" "unprognostic (4.57e-3)" CLPX ENSG00000166855 "Caseinolytic mitochondrial matrix peptidase chaperone subunit X" O76031 15 65148219-65185342 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Chaperone, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 218.5;Late spermatids: 423.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040262, HPA048199" Approved Supported "Nucleoplasm,Mitochondria,Cytosol,Equatorial segment,Perinuclear theca" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 76: Non-specific - Metabolism" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 19 Mitochondria "Nucleoplasm, Cytosol, Equatorial segment, Perinuclear theca" "HPA040262: , HPA048199: " "unprognostic (4.49e-2)" "unprognostic (4.66e-2)" "unprognostic (4.39e-1)" "unprognostic (2.88e-1)" "unprognostic (1.91e-2)" "unprognostic (3.35e-1)" "unprognostic (1.59e-2)" "unprognostic (4.74e-3)" "unprognostic (3.68e-1)" "potential prognostic unfavorable (5.29e-4)" "validated prognostic favorable (1.57e-4)" "validated prognostic favorable (5.57e-5)" "unprognostic (1.46e-3)" "potential prognostic favorable (7.23e-4)" "unprognostic (1.79e-1)" "unprognostic (1.99e-1)" "unprognostic (2.52e-1)" "unprognostic (2.45e-1)" "unprognostic (5.86e-3)" "unprognostic (2.66e-2)" "unprognostic (3.87e-2)" "unprognostic (3.48e-1)" "unprognostic (1.68e-1)" "unprognostic (8.65e-2)" "unprognostic (4.85e-2)" "unprognostic (2.97e-1)" "unprognostic (6.50e-2)" "unprognostic (5.38e-2)" "unprognostic (3.12e-1)" "unprognostic (2.68e-1)" "unprognostic (2.97e-3)" CLRN1 "RP61, USH3, USH3A" ENSG00000163646 "Clarin 1" P58418 3 150926163-150972727 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hearing, Sensory transduction, Vision" "Deafness, Disease variant, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "adrenal gland: 4.7;retina: 11.8" "Cell type enriched" "Detected in some" 8 "Müller glia: 102.1" "Cell type enhanced" "Detected in some" "lower rhombic lip: 1.4;thalamic excitatory: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA054031 Uncertain "Vesicles,Centrosome,Basal body" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 11: Muller glia cells - Retinal homeostasis" 23 Centrosome "Vesicles, Basal body" "HPA054031: " CLRN2 DFNB117 ENSG00000249581 "Clarin 2" A0PK11 4 17515165-17527104 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Hearing "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Differentiating spermatogonia: 1.2;Undifferentiated spermatogonia: 3.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA042407 Uncertain NA NA "Cluster 106: Spermatogonia - Spermatogonial differentiation" 16 "HPA042407: " CLRN3 "MGC32871, TMEM12, USH3AL1" ENSG00000180745 "Clarin 3" Q8NCR9 10 127877841-127892941 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 83.9;kidney: 40.9;liver: 74.6" "Cell type enhanced" "Detected in some" "Colonocytes: 108.9;Enteric stem cells: 44.6;Enteric transient amplifying cells: 52.6;Enterocytes: 156.9;Epididymal efferent duct absorptive cells: 62.0;Gastric progenitor cells: 38.5;Goblet cells: 96.7;Hepatocytes: 50.6;Neuroendocrine cells: 38.4;Paneth cells: 46.4;Proximal tubule cells: 31.1;Tuft cells: 196.0" "Cell type enhanced" "Detected in some" "thalamic excitatory: 1.2" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 68.4;Kidney Renal Clear Cell Carcinoma (TCGA): 59.4;Rectum Adenocarcinoma (TCGA): 66.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "colorectal cancer: 37.8;Gastric cancer: 20.8" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Pancreas - Ductal cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA014482 Approved NA NA "Cluster 77: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 2 "HPA014482: " "unprognostic (3.51e-1)" "unprognostic (4.24e-2)" "unprognostic (2.25e-1)" "potential prognostic favorable (1.23e-8)" "unprognostic (4.32e-2)" "unprognostic (1.04e-1)" "unprognostic (1.12e-1)" "unprognostic (1.06e-1)" "unprognostic (5.52e-2)" "unprognostic (1.06e-1)" "unprognostic (1.93e-1)" "unprognostic (1.08e-1)" "potential prognostic favorable (2.55e-4)" CLSPN ENSG00000092853 Claspin Q9HAW4 1 35720218-35769978 "Essential proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 10.6;lymphoid tissue: 7.3;retina: 6.3;testis: 5.4" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 176.0;Early primary spermatocytes: 583.4;Erythrocyte progenitors: 151.6;Extravillous trophoblasts: 63.5;Megakaryocyte progenitors: 137.0;Monocyte progenitors: 186.8;Neutrophil progenitors: 62.6;Oocytes: 128.9;Rod photoreceptor cells: 104.2" "Cell type enhanced" "Detected in many" "hippocampal dentate gyrus: 18.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Region enriched" "Detected in some" 6 "basal ganglia: 7.8" "Low region specificity" "Detected in all" "HPA026305, HPA026312" Enhanced "Nucleoplasm,Golgi apparatus" Yes Yes "Cluster 44: Bone marrow - Nuclear processes" "Cluster 51: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 3: Early primary spermatocytes - Early meiosis" 39 "Nucleoplasm, Golgi apparatus" "HPA026305: , HPA026312: " "unprognostic (3.00e-1)" "unprognostic (6.55e-2)" "unprognostic (3.97e-2)" "unprognostic (3.95e-1)" "unprognostic (9.73e-2)" "unprognostic (1.00e-2)" "unprognostic (2.53e-1)" "unprognostic (3.82e-2)" "unprognostic (3.02e-2)" "unprognostic (1.88e-2)" "unprognostic (3.23e-2)" "potential prognostic unfavorable (1.89e-7)" "validated prognostic unfavorable (1.44e-5)" "validated prognostic unfavorable (3.13e-5)" "unprognostic (2.38e-1)" "unprognostic (1.54e-2)" "unprognostic (3.68e-2)" "unprognostic (9.77e-2)" "potential prognostic unfavorable (1.53e-4)" "unprognostic (4.42e-3)" "unprognostic (6.86e-2)" "unprognostic (3.08e-2)" "unprognostic (9.71e-3)" "potential prognostic favorable (4.91e-4)" "unprognostic (2.00e-1)" "unprognostic (1.98e-1)" CLSTN1 "CDHR12, CSTN1, KIAA0911" ENSG00000171603 "Calsyntenin 1" O94985 1 9728926-9823984 "Cancer-related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 614.8;Rod photoreceptor cells: 376.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Pituitary gland - Thyrotropes, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012412, HPA077705" Enhanced NA NA 27000000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 27: Cerebellum - Synaptic function" "Cluster 14: Neurons - Synaptic function" "Cluster 37: Non-specific - mRNA processing" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 8 "HPA012412: , HPA077705: " "unprognostic (2.72e-1)" "unprognostic (1.99e-2)" "unprognostic (2.30e-1)" "unprognostic (5.40e-3)" "unprognostic (3.51e-2)" "unprognostic (1.91e-1)" "unprognostic (2.89e-1)" "unprognostic (6.51e-2)" "unprognostic (3.40e-1)" "unprognostic (1.67e-1)" "potential prognostic favorable (3.72e-7)" "unprognostic (6.00e-3)" "unprognostic (2.74e-2)" "unprognostic (6.08e-3)" "potential prognostic unfavorable (4.67e-4)" "unprognostic (3.86e-2)" "unprognostic (1.40e-3)" "unprognostic (2.95e-2)" "unprognostic (8.23e-2)" "unprognostic (8.78e-2)" "unprognostic (2.89e-1)" "unprognostic (2.80e-1)" "unprognostic (2.36e-1)" "unprognostic (1.66e-1)" "unprognostic (6.80e-2)" "unprognostic (2.83e-1)" "unprognostic (1.75e-1)" "unprognostic (1.13e-1)" "unprognostic (1.84e-1)" "unprognostic (3.88e-2)" "unprognostic (8.58e-2)" CLSTN2 "CDHR13, CS2, CSTN2, FLJ39113" ENSG00000158258 "Calsyntenin 2" Q9H4D0 3 139935185-140577397 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.7;ovary: 39.7" "Cell type enhanced" "Detected in many" "Adipocytes: 1124.0;Adrenal medulla cells: 457.4;Brain excitatory neurons: 566.4;Early spermatids: 286.7;Fibro-adipogenic progenitors: 206.1;Other brain neurons: 488.1;Ovarian stromal cells: 496.8;Pericytes: 326.4;Proximal tubule cells: 284.9;Retinal ganglion cells: 301.3;Thymic myoid cells: 349.4" "Cell type enhanced" "Detected in all" "hippocampal CA4: 2121.8;hippocampal dentate gyrus: 2288.4" "Group enriched" "Detected in many" 5 "Breast Invasive Carcinoma (TCGA): 23.9;Kidney Renal Papillary Cell Carcinoma (TCGA): 7.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Bone cancer: 20.0;testis cancer: 39.3" "Liver - Hepatic stellate cells, Pituitary gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031342, HPA061800" Approved Uncertain "Vesicles,Cytokinetic bridge" Yes No 35000 "Cluster 75: Ovary - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" Vesicles "Cytokinetic bridge" "HPA031342: , HPA061800: " "unprognostic (1.00e-2)" "unprognostic (1.79e-1)" "unprognostic (1.06e-1)" "unprognostic (2.67e-2)" "unprognostic (4.82e-3)" "unprognostic (2.34e-3)" "unprognostic (5.92e-2)" "unprognostic (2.44e-1)" "unprognostic (1.25e-1)" "unprognostic (2.19e-1)" "unprognostic (5.69e-2)" "unprognostic (5.44e-2)" "unprognostic (2.19e-1)" "unprognostic (1.09e-1)" "unprognostic (3.42e-1)" "unprognostic (3.08e-2)" "unprognostic (2.30e-1)" CLSTN3 "CDHR14, CSTN3, KIAA0726" ENSG00000139182 "Calsyntenin 3" Q9BQT9 12 7129698-7158945 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 137.4" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 99.6;Brain inhibitory neurons: 95.9;Distal convoluted tubule cells: 20.3;Loop of henle epithelial cells: 18.7;Oligodendrocyte progenitor cells: 17.5;Other brain neurons: 90.7;Proximal tubule cells: 38.3;Renal connecting tubule cells: 16.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 6.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 340000 "Cluster 15: NK-cells - Unknown function" "Cluster 27: Cerebellum - Synaptic function" "Cluster 1: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 39 "unprognostic (4.18e-3)" "potential prognostic favorable (4.85e-4)" "unprognostic (7.18e-2)" "unprognostic (1.09e-3)" "unprognostic (3.45e-3)" "unprognostic (2.15e-1)" "unprognostic (3.44e-2)" "unprognostic (9.17e-2)" "unprognostic (4.39e-2)" "unprognostic (4.87e-2)" "unprognostic (1.99e-2)" "unprognostic (3.67e-2)" "unprognostic (9.70e-2)" "unprognostic (1.04e-1)" "unprognostic (8.60e-2)" "unprognostic (1.08e-1)" "unprognostic (2.25e-1)" "unprognostic (4.02e-2)" "unprognostic (1.07e-1)" "unprognostic (2.28e-1)" "unprognostic (1.60e-1)" "potential prognostic favorable (2.56e-5)" "unprognostic (4.87e-3)" "unprognostic (1.57e-1)" "unprognostic (5.96e-2)" "unprognostic (7.86e-3)" "unprognostic (2.79e-1)" "unprognostic (1.82e-2)" "unprognostic (1.18e-1)" "unprognostic (4.28e-2)" "unprognostic (1.79e-1)" CLTA Lca ENSG00000122705 "Clathrin light chain A" P09496 9 36190856-36304781 "Plasma proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1160.4;Esophageal apical cells: 1200.9;Hofbauer cells: 1405.7;Syncytiotrophoblasts: 1536.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002665, HPA050918, HPA054667" Enhanced Supported "Golgi apparatus,Endosomes,Lysosomes,Plasma membrane,Mitotic spindle,Primary cilium" Yes NA 630000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 208 "Endosomes, Lysosomes" "Golgi apparatus, Plasma membrane, Mitotic spindle, Primary cilium" "CAB002665: , HPA050918: , HPA054667: " "unprognostic (5.09e-3)" "unprognostic (4.59e-3)" "unprognostic (2.76e-2)" "unprognostic (3.51e-1)" "unprognostic (2.37e-2)" "unprognostic (3.34e-2)" "unprognostic (2.99e-1)" "unprognostic (1.26e-2)" "unprognostic (4.94e-2)" "unprognostic (1.39e-1)" "potential prognostic favorable (1.60e-6)" "unprognostic (1.00e-2)" "unprognostic (1.00e-1)" "validated prognostic unfavorable (2.99e-6)" "validated prognostic unfavorable (2.68e-5)" "unprognostic (7.50e-2)" "unprognostic (4.20e-3)" "unprognostic (2.98e-1)" "unprognostic (1.18e-1)" "unprognostic (5.05e-3)" "unprognostic (3.37e-1)" "unprognostic (4.44e-2)" "unprognostic (2.70e-1)" "unprognostic (3.97e-1)" "unprognostic (1.15e-1)" "unprognostic (3.08e-1)" "unprognostic (2.13e-1)" "unprognostic (7.18e-2)" "unprognostic (1.06e-1)" "unprognostic (2.11e-3)" "unprognostic (2.42e-1)" CLTB Lcb ENSG00000175416 "Clathrin light chain B" P09497 5 176392501-176416539 "Plasma proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 688.4;Esophageal apical cells: 4480.3;Esophageal basal cells: 952.5;Esophageal suprabasal cells: 2587.4;Extravillous trophoblasts: 907.9;Suprabasal keratinocytes: 993.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Smooth muscle cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003692, HPA036458" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA 12000 "Cluster 45: Eosinophils - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 79 Vesicles "Plasma membrane, Cytosol" "CAB003692: , HPA036458: " "unprognostic (5.51e-2)" "unprognostic (1.76e-1)" "unprognostic (7.25e-2)" "unprognostic (1.11e-1)" "unprognostic (1.95e-1)" "unprognostic (1.09e-3)" "unprognostic (8.99e-3)" "unprognostic (3.26e-1)" "unprognostic (1.25e-1)" "unprognostic (1.46e-2)" "unprognostic (9.93e-3)" "unprognostic (1.33e-2)" "unprognostic (6.38e-2)" "unprognostic (4.25e-3)" "unprognostic (2.06e-1)" "potential prognostic unfavorable (3.51e-4)" "unprognostic (7.32e-2)" "unprognostic (1.08e-1)" "unprognostic (1.20e-1)" "unprognostic (2.26e-1)" "unprognostic (3.51e-3)" "unprognostic (2.58e-3)" "unprognostic (8.58e-2)" "unprognostic (2.61e-1)" "unprognostic (4.80e-1)" "unprognostic (6.16e-2)" "unprognostic (3.68e-1)" "unprognostic (2.46e-2)" "unprognostic (1.36e-1)" "unprognostic (7.14e-2)" "unprognostic (4.77e-2)" CLTC "CLTCL2, Hc" ENSG00000141367 "Clathrin heavy chain" Q00610 17 59619684-59696956 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Autophagy, Cell cycle, Cell division, Mitosis" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 602.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Colon - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010389, CAB011571, CAB017155, HPA059143" Approved Enhanced "Endosomes,Lysosomes,Mitotic spindle,Centriolar satellite,Cytosol,Mid piece" Yes No 15000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 36: Brain & Liver - Signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 129 "Endosomes, Lysosomes" "Mitotic spindle, Centriolar satellite, Cytosol, Mid piece" "CAB010389: , CAB011571: , CAB017155: , HPA059143: " "unprognostic (1.13e-1)" "unprognostic (1.14e-2)" "unprognostic (2.82e-3)" "unprognostic (1.39e-3)" "unprognostic (1.36e-3)" "unprognostic (1.68e-1)" "unprognostic (2.42e-1)" "unprognostic (9.29e-3)" "unprognostic (1.36e-2)" "potential prognostic unfavorable (3.40e-4)" "potential prognostic favorable (5.20e-6)" "unprognostic (6.26e-2)" "unprognostic (9.96e-2)" "potential prognostic unfavorable (6.05e-5)" "unprognostic (1.24e-3)" "unprognostic (5.75e-2)" "unprognostic (1.40e-2)" "unprognostic (1.33e-1)" "unprognostic (2.55e-1)" "unprognostic (2.41e-1)" "unprognostic (3.80e-1)" "unprognostic (2.30e-2)" "unprognostic (2.74e-1)" "unprognostic (2.92e-1)" "unprognostic (2.51e-1)" "unprognostic (3.72e-3)" "unprognostic (7.30e-2)" "unprognostic (3.26e-1)" "unprognostic (3.41e-1)" "unprognostic (1.02e-1)" "unprognostic (2.38e-1)" CLTCL1 "CHC22, CLH22, CLTCL, CLTD" ENSG00000070371 "Clathrin heavy chain like 1" P53675 22 19179473-19291719 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "skeletal muscle: 180.9;testis: 45.3;tongue: 57.3" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 131.7;Myonuclei: 629.8;Neutrophil progenitors: 463.3;Retinal ganglion cells: 239.5;Somatotrophs: 147.2;Thymic myoid cells: 500.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "classical monocyte: 2.1;neutrophil: 5.2" "Group enriched" "Detected in many" 20 "granulocytes: 5.2;monocytes: 2.1" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Pituitary gland - Somatotropes, Testis - Early spermatids" "HPA075327, HPA075795" Enhanced Approved Vesicles NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 45: Non-specific - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 13 Vesicles "HPA075327: , HPA075795: " "unprognostic (1.37e-1)" "unprognostic (8.62e-3)" "unprognostic (7.77e-2)" "unprognostic (1.08e-1)" "unprognostic (6.40e-2)" "unprognostic (9.32e-2)" "unprognostic (8.97e-2)" "unprognostic (3.92e-2)" "unprognostic (2.08e-3)" "unprognostic (1.27e-2)" "potential prognostic unfavorable (4.53e-4)" "unprognostic (3.36e-2)" "unprognostic (9.03e-3)" "unprognostic (6.70e-2)" "unprognostic (1.54e-3)" "unprognostic (1.31e-3)" "unprognostic (7.38e-2)" "unprognostic (4.80e-2)" "unprognostic (1.19e-3)" "unprognostic (8.20e-3)" "unprognostic (4.63e-3)" "unprognostic (8.27e-2)" "unprognostic (7.81e-3)" "unprognostic (4.85e-2)" "unprognostic (1.12e-1)" "unprognostic (5.17e-2)" "unprognostic (1.75e-2)" "unprognostic (4.94e-3)" "unprognostic (1.77e-1)" "unprognostic (4.30e-2)" "potential prognostic unfavorable (7.40e-4)" CLTRN "NX17, TMEM27" ENSG00000147003 "Collectrin, amino acid transport regulator" Q9HBJ8 X 15627318-15675012 "Metabolic proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "kidney: 453.6" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 17.6;Distal convoluted tubule cells: 4.1;Ependymal cells: 4.3;Loop of henle epithelial cells: 10.5;Podocytes: 4.6;Proximal tubule cells: 53.2;Renal collecting duct intercalated cells: 6.0;Renal collecting duct principal cells: 5.0;Retinal pigment epithelial cells: 4.3" "Cell type enriched" "Detected in many" 6 "choroid plexus epithelial cell: 27.5" "Group enriched" "Detected in many" 27 "Kidney Renal Clear Cell Carcinoma (TCGA): 177.6;Kidney Renal Papillary Cell Carcinoma (TCGA): 266.7" "Region enriched" "Detected in all" 14 "choroid plexus: 36.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Alveolar cells type 2, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA048543 Enhanced Approved "Endoplasmic reticulum,Vesicles" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 72: Kidney - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 88: Proximal tubular cells - Transmembrane transport" 3 "Endoplasmic reticulum, Vesicles" "HPA048543: " "unprognostic (2.10e-1)" "unprognostic (8.24e-2)" "unprognostic (6.20e-2)" "unprognostic (1.23e-1)" "unprognostic (8.33e-2)" "unprognostic (6.45e-2)" "unprognostic (2.53e-1)" "potential prognostic favorable (1.54e-13)" "unprognostic (1.77e-3)" "potential prognostic favorable (3.90e-4)" "unprognostic (1.08e-1)" "unprognostic (1.43e-2)" "unprognostic (9.42e-2)" "unprognostic (8.15e-2)" "unprognostic (5.22e-3)" "unprognostic (1.87e-2)" "unprognostic (8.13e-3)" "unprognostic (1.27e-2)" "unprognostic (2.25e-1)" "unprognostic (1.57e-1)" "unprognostic (8.31e-2)" "unprognostic (2.16e-1)" "unprognostic (1.39e-1)" CLU "APOJ, CLI, CLU1, CLU2, KUB1, SGP-2, SP-40, TRPM-2" ENSG00000120885 Clusterin P10909 8 27596917-27614700 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Complement pathway, Immunity, Innate immunity" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 9103.3" "Cell type enhanced" "Detected in all" "Endometrial secretory cells: 6414.6;Epididymal basal cells: 3407.6;Epididymal efferent duct absorptive cells: 6925.0;Epididymal principal cells: 6408.2;Fallopian secretory cells: 6163.8;Hepatocytes: 4532.6;Müller glia: 7063.0;Ocular epithelial cells: 11976.2;Pancreatic duct cells: 3168.6;Platelets: 3677.9;Submucosal glandular cells: 4613.4" "Cell type enhanced" "Detected in all" "astrocyte: 1942.6;ependymal cell: 2071.7" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 20296.0;Thyroid Carcinoma (TCGA): 13243.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 10 "basophil: 773.3" "Lineage enriched" "Detected in all" 33 "granulocytes: 773.3" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Lung - Fibroblasts_2, Prostate - Smooth muscle cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000572, CAB016253, HPA075983, CAB080180" Enhanced Supported Cytosol "Secreted to blood" "Complement pathway" NA NA 169000000000 48000000000 "Cluster 41: Basophils - Unknown function" "Cluster 22: Epididymis - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 100: Stratified epithelial cells - Barrier functions" 50 Cytosol "CAB016253: , CAB080180: , HPA000572: , HPA075983: " "unprognostic (3.04e-1)" "unprognostic (1.06e-2)" "unprognostic (8.82e-2)" "unprognostic (4.33e-2)" "unprognostic (3.32e-2)" "unprognostic (7.11e-2)" "unprognostic (9.27e-2)" "potential prognostic unfavorable (3.61e-4)" "unprognostic (1.58e-1)" "unprognostic (2.85e-2)" "unprognostic (1.09e-3)" "unprognostic (7.17e-3)" "unprognostic (8.77e-2)" "unprognostic (1.15e-3)" "potential prognostic favorable (5.56e-5)" "unprognostic (1.08e-1)" "unprognostic (1.47e-2)" "unprognostic (7.85e-2)" "unprognostic (1.38e-2)" "unprognostic (3.10e-1)" "unprognostic (1.48e-1)" "unprognostic (3.33e-2)" "unprognostic (1.13e-1)" "unprognostic (4.24e-2)" "unprognostic (6.55e-3)" "unprognostic (2.37e-2)" "unprognostic (1.94e-1)" "unprognostic (2.20e-2)" "unprognostic (1.34e-1)" "unprognostic (1.02e-3)" "unprognostic (4.13e-1)" CLUAP1 "CFAP22, FAP22, FLJ13297, IFT38, KIAA0643" ENSG00000103351 "Clusterin associated protein 1" Q96AJ1 16 3500976-3539048 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 163.4;Fallopian tube ciliated cells: 137.2;Late primary spermatocytes: 222.2;Respiratory ciliated cells: 218.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036976, HPA044191" Uncertain Supported "Nucleoplasm,Vesicles,Actin filaments,Primary cilium" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" 46 "Nucleoplasm, Primary cilium" "Vesicles, Actin filaments" "HPA036976: , HPA044191: " "unprognostic (4.81e-1)" "unprognostic (3.45e-2)" "unprognostic (2.17e-1)" "unprognostic (2.53e-2)" "unprognostic (1.63e-1)" "unprognostic (8.75e-3)" "unprognostic (2.32e-1)" "unprognostic (1.48e-1)" "unprognostic (2.30e-1)" "unprognostic (3.72e-2)" "potential prognostic favorable (4.33e-7)" "unprognostic (1.30e-2)" "unprognostic (1.77e-1)" "unprognostic (9.24e-2)" "unprognostic (8.63e-2)" "unprognostic (3.84e-2)" "unprognostic (2.09e-1)" "unprognostic (6.62e-2)" "unprognostic (5.19e-2)" "unprognostic (1.18e-1)" "unprognostic (6.66e-2)" "unprognostic (2.49e-2)" "unprognostic (8.99e-2)" "unprognostic (8.31e-2)" "unprognostic (7.83e-3)" "unprognostic (1.32e-2)" "unprognostic (2.41e-1)" "unprognostic (2.39e-2)" "unprognostic (2.95e-1)" "unprognostic (2.51e-1)" "unprognostic (7.64e-3)" CLUH "CLU1, KIAA0664" ENSG00000132361 "Clustered mitochondria homolog" O75153 17 2689386-2712663 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 225.8;Hepatocytes: 148.3;Oocytes: 96.7;Proximal tubule cells: 94.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Kidney - Macrophages, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031505, HPA044346" Uncertain Approved "Nucleoli fibrillar center,Vesicles" NA NA 7400 "Cluster 13: Non-specific - Mitochondria" "Cluster 24: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 28 Vesicles "Nucleoli fibrillar center" "HPA031505: , HPA044346: " "unprognostic (1.25e-1)" "unprognostic (3.94e-3)" "unprognostic (2.55e-1)" "unprognostic (2.63e-1)" "unprognostic (2.79e-1)" "unprognostic (2.53e-1)" "unprognostic (3.26e-2)" "unprognostic (1.33e-2)" "unprognostic (6.30e-2)" "potential prognostic favorable (7.21e-5)" "unprognostic (6.53e-3)" "potential prognostic favorable (5.84e-4)" "unprognostic (3.30e-2)" "unprognostic (5.83e-2)" "unprognostic (1.96e-1)" "unprognostic (5.81e-2)" "unprognostic (5.34e-2)" "unprognostic (6.89e-2)" "unprognostic (9.53e-2)" "unprognostic (2.41e-2)" "unprognostic (4.01e-2)" "unprognostic (5.33e-2)" "unprognostic (6.48e-3)" "unprognostic (7.55e-2)" "unprognostic (2.14e-1)" "unprognostic (9.47e-2)" "unprognostic (8.59e-2)" "unprognostic (7.39e-3)" "unprognostic (6.29e-2)" CLUL1 ENSG00000079101 "Clusterin like 1" Q15846 18 596988-650334 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "retina: 275.9" "Cell type enriched" "Detected in many" 12 "Rod photoreceptor cells: 404.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Prostate - Prostate glandular cells, Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "CAB025264, HPA075240" Enhanced Approved "Endoplasmic reticulum,Plasma membrane" "Secreted in other tissues" "No annotated function" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 42: Retina - Visual perception" "Cluster 11: White matter - Signal transduction" "Cluster 11: Neuronal - Sensory perception" "Cluster 79: Photoreceptor cells - Phototransduction" "Endoplasmic reticulum" "Plasma membrane" "CAB025264: , HPA075240: " "unprognostic (4.54e-3)" "unprognostic (2.73e-1)" "unprognostic (1.04e-1)" "potential prognostic favorable (8.69e-4)" "unprognostic (2.24e-1)" "unprognostic (1.68e-1)" "unprognostic (4.32e-2)" "unprognostic (1.58e-2)" "unprognostic (3.77e-1)" "unprognostic (1.03e-1)" "unprognostic (3.02e-3)" "unprognostic (1.90e-1)" "unprognostic (2.18e-1)" "unprognostic (3.46e-3)" "unprognostic (1.94e-2)" "unprognostic (9.46e-3)" "unprognostic (5.11e-2)" "unprognostic (1.07e-1)" "potential prognostic favorable (5.39e-4)" "unprognostic (2.10e-2)" "unprognostic (1.42e-2)" "unprognostic (5.55e-2)" "unprognostic (1.87e-1)" "unprognostic (7.75e-2)" "unprognostic (3.19e-1)" "unprognostic (5.19e-2)" "unprognostic (2.94e-1)" "unprognostic (1.40e-3)" "unprognostic (1.56e-1)" CLVS1 "C6orf212L, CRALBPL, MGC34646, RLBP1L1" ENSG00000177182 "Clavesin 1" Q8IUQ0 8 61057158-61501645 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.6;retina: 4.8" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 145.3;Brain inhibitory neurons: 199.5;Corticotrophs: 141.2;Ependymal cells: 150.0;Gonadotrophs: 149.3;Lactotrophs: 147.3;Müller glia: 200.3;Oligodendrocyte progenitor cells: 123.6;Other brain neurons: 181.4;Retinal amacrine cells: 66.3;Retinal ganglion cells: 69.5;Somatotrophs: 72.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 7.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 2.8;Neuroblastoma: 2.7" "Colon - Colon enteroendocrine cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076650 Approved NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 1 "HPA076650: " "unprognostic (3.00e-3)" "unprognostic (2.73e-3)" "unprognostic (2.40e-1)" "unprognostic (3.46e-1)" "unprognostic (1.55e-1)" "unprognostic (1.18e-1)" "unprognostic (2.90e-1)" "unprognostic (1.61e-3)" "unprognostic (1.27e-2)" "unprognostic (2.96e-1)" "unprognostic (1.36e-2)" "unprognostic (5.17e-2)" "unprognostic (3.17e-1)" "unprognostic (1.42e-1)" "unprognostic (2.51e-2)" CLVS2 "bA160A10.4, C6orf212, C6orf213, RLBP1L2" ENSG00000146352 "Clavesin 2" Q5SYC1 6 122996235-123072925 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 16.5;retina: 7.6" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 54.4;Brain excitatory neurons: 180.5;Brain inhibitory neurons: 140.3;Corticotrophs: 222.4;Gonadotrophs: 93.6;Lactotrophs: 56.1;Müller glia: 152.5;Other brain neurons: 69.2;Retinal amacrine cells: 51.8;Retinal ganglion cells: 123.6;Somatotrophs: 75.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in single" "Glioblastoma Multiforme (TCGA): 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Bone cancer: 7.5;Neuroblastoma: 11.7" "Adrenal gland - Adrenal medulla cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043764 Uncertain NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 35: Non-specific - DNA binding" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 13 "HPA043764: " "unprognostic (1.42e-1)" "unprognostic (3.15e-1)" CLXN "EFCAB1, FLJ11767, ODAD5" ENSG00000034239 Calaxin Q9HAE3 8 48710789-48735311 "Predicted intracellular proteins" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "choroid plexus: 51.3;fallopian tube: 86.1;testis: 35.9" "Group enriched" "Detected in some" 4 "Early spermatids: 621.6;Endometrial ciliated cells: 210.8;Ependymal cells: 268.0;Epididymal efferent duct ciliated cells: 347.5;Fallopian tube ciliated cells: 451.3;Late primary spermatocytes: 227.1;Late spermatids: 735.6;Respiratory ciliated cells: 517.7" "Group enriched" "Detected in many" 30 "choroid plexus epithelial cell: 103.8;ependymal cell: 312.2" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 13.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.2" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in some" "head and neck cancer: 2.9" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023527 Enhanced Approved "Nucleoplasm,Mid piece,Principal piece" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" "Mid piece, Principal piece" Nucleoplasm "HPA023527: " "unprognostic (3.40e-2)" "unprognostic (6.17e-2)" "unprognostic (2.59e-1)" "unprognostic (1.28e-3)" "unprognostic (1.32e-1)" "unprognostic (2.12e-1)" "unprognostic (1.11e-1)" "unprognostic (3.06e-1)" "unprognostic (1.43e-1)" "unprognostic (1.92e-1)" "unprognostic (1.27e-1)" "unprognostic (1.16e-1)" "unprognostic (2.63e-1)" "unprognostic (2.08e-1)" "potential prognostic unfavorable (2.80e-4)" "unprognostic (1.06e-1)" "unprognostic (1.13e-1)" "unprognostic (5.72e-2)" CLYBL CLB ENSG00000125246 "Citramalyl-CoA lyase" Q8N0X4 13 99606669-99909459 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Lyase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 99.8" "Cell type enhanced" "Detected in many" "Bergmann glia: 257.0;Choroid plexus epithelial cells: 518.4;Ependymal cells: 266.7;Renal collecting duct intercalated cells: 325.8" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 486.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039959, HPA040691" Enhanced NA NA 120000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 76: Non-specific - Metabolism" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 19: Non-specific - Unknown function" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 1 "HPA039959: , HPA040691: " "unprognostic (5.87e-2)" "unprognostic (9.44e-2)" "unprognostic (1.10e-1)" "unprognostic (2.07e-1)" "unprognostic (3.79e-2)" "unprognostic (1.64e-1)" "unprognostic (2.01e-1)" "unprognostic (3.42e-1)" "unprognostic (3.46e-2)" "unprognostic (1.47e-2)" "validated prognostic favorable (8.71e-10)" "validated prognostic favorable (5.60e-4)" "potential prognostic favorable (1.31e-7)" "unprognostic (3.45e-3)" "unprognostic (1.15e-2)" "unprognostic (9.91e-3)" "unprognostic (1.76e-1)" "unprognostic (9.60e-2)" "unprognostic (2.15e-3)" "unprognostic (6.93e-2)" "unprognostic (1.02e-1)" "unprognostic (9.92e-2)" "unprognostic (3.04e-1)" "unprognostic (1.28e-1)" "unprognostic (7.77e-2)" "unprognostic (2.48e-1)" "unprognostic (2.05e-1)" "unprognostic (1.59e-1)" "unprognostic (1.06e-1)" "unprognostic (2.00e-2)" "unprognostic (9.84e-2)" CMA1 ENSG00000092009 "Chymase 1" P23946 14 24505353-24508265 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 17.3" "Cell type enriched" "Detected in some" 30 "Mast cells: 160.7" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lymphoma: 1.9" "Adipose subcutaneous - Mast cells, Adipose visceral - Mast cells, Colon - Mast cells, Minor Salivary Gland - Mast cells, Stomach - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000363, HPA052634" Enhanced Supported "Cytosol,Cytoplasmic bodies" "Secreted to blood" Enzyme NA NA 3000000 430000 "Cluster 11: Esophagus - Basic cellular processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 58: Mast cells - Allergic inflammatory responses" 16 "Cytoplasmic bodies" Cytosol "CAB000363: , HPA052634: " "unprognostic (1.88e-1)" "unprognostic (9.38e-2)" "unprognostic (3.92e-2)" "unprognostic (1.82e-2)" "unprognostic (2.20e-1)" "unprognostic (2.97e-1)" "unprognostic (1.83e-1)" "unprognostic (7.85e-3)" "unprognostic (2.77e-2)" CMAS ENSG00000111726 "Cytidine monophosphate N-acetylneuraminic acid synthetase" Q8NFW8 12 22046218-22065674 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 887.0;Megakaryocytes: 525.4;Syncytiotrophoblasts: 884.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039905 Supported Uncertain Nucleoli,Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 76: Non-specific - Metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 38: Non-specific - Transcription" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 10 Cytosol Nucleoli "HPA039905: " "unprognostic (1.03e-1)" "unprognostic (1.30e-2)" "unprognostic (5.11e-2)" "unprognostic (1.04e-1)" "unprognostic (1.72e-1)" "potential prognostic favorable (8.24e-4)" "unprognostic (6.72e-2)" "unprognostic (1.40e-1)" "unprognostic (7.13e-2)" "unprognostic (4.29e-1)" "unprognostic (9.31e-2)" "unprognostic (1.81e-1)" "unprognostic (2.63e-1)" "unprognostic (5.50e-2)" "potential prognostic unfavorable (6.01e-6)" "validated prognostic unfavorable (8.08e-4)" "validated prognostic unfavorable (4.37e-4)" "unprognostic (4.49e-2)" "unprognostic (1.34e-1)" "potential prognostic unfavorable (6.68e-4)" "unprognostic (9.18e-2)" "unprognostic (3.13e-1)" "unprognostic (1.01e-3)" "unprognostic (1.70e-1)" "unprognostic (2.87e-1)" "unprognostic (1.12e-1)" "unprognostic (1.66e-1)" "unprognostic (2.44e-1)" "unprognostic (3.08e-2)" "unprognostic (2.00e-1)" "unprognostic (6.94e-2)" CMBL FLJ23617 ENSG00000164237 "Carboxymethylenebutenolidase homolog" Q96DG6 5 10275875-10307902 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 156.9;liver: 160.9;skeletal muscle: 153.5" "Cell type enhanced" "Detected in many" "Colonocytes: 204.8;Enteric stem cells: 153.4;Enteric transient amplifying cells: 213.9;Enterocytes: 716.7;Hepatocytes: 231.5;Proximal tubule cells: 117.1;Thymic myoid cells: 136.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Stomach - Gastric mucous cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036571 Uncertain NA NA 630000 "Cluster 76: Non-specific - Metabolism" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 1: Enterocytes - Absorption and Digestion" 2 "HPA036571: " "unprognostic (1.37e-1)" "unprognostic (1.25e-2)" "unprognostic (1.42e-3)" "unprognostic (1.26e-1)" "unprognostic (6.99e-3)" "unprognostic (3.69e-1)" "unprognostic (1.55e-1)" "potential prognostic unfavorable (2.03e-5)" "unprognostic (1.90e-1)" "unprognostic (4.67e-2)" "validated prognostic favorable (1.92e-6)" "validated prognostic favorable (2.16e-4)" "unprognostic (5.66e-2)" "unprognostic (9.18e-2)" "unprognostic (1.12e-2)" "unprognostic (2.55e-2)" "unprognostic (1.46e-2)" "unprognostic (2.15e-2)" "unprognostic (2.89e-2)" "unprognostic (2.01e-3)" "unprognostic (8.44e-2)" "unprognostic (9.54e-2)" "unprognostic (1.32e-1)" "unprognostic (2.30e-1)" "unprognostic (4.25e-2)" "unprognostic (4.09e-3)" "unprognostic (2.74e-2)" "unprognostic (2.18e-1)" "unprognostic (1.02e-1)" "unprognostic (1.82e-1)" "unprognostic (5.07e-3)" CMC1 "C3orf68, MGC61571" ENSG00000187118 "C-X9-C motif containing 1" Q7Z7K0 3 28241584-28325142 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "NK-cells: 491.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "NK-cell: 162.6" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Spleen - NK-cells (Spleen), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043333 Approved NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 1 "HPA043333: " "unprognostic (1.43e-1)" "potential prognostic unfavorable (3.85e-4)" "unprognostic (1.25e-1)" "unprognostic (6.59e-2)" "unprognostic (6.18e-3)" "unprognostic (8.83e-3)" "unprognostic (1.28e-2)" "unprognostic (7.64e-2)" "unprognostic (2.08e-2)" "unprognostic (1.54e-2)" "unprognostic (4.08e-3)" "unprognostic (5.46e-2)" "unprognostic (1.14e-1)" "unprognostic (3.59e-2)" "potential prognostic unfavorable (5.23e-5)" "unprognostic (2.94e-2)" "unprognostic (4.69e-2)" "unprognostic (8.59e-2)" "unprognostic (1.66e-1)" "unprognostic (1.39e-3)" "unprognostic (1.18e-1)" "unprognostic (1.24e-1)" "unprognostic (4.64e-2)" "unprognostic (9.17e-3)" "unprognostic (3.49e-2)" "unprognostic (1.94e-1)" "unprognostic (1.88e-2)" "unprognostic (2.20e-1)" "unprognostic (2.89e-1)" "unprognostic (1.87e-1)" "unprognostic (3.82e-2)" CMC2 "C16orf61, DC13, MGC45036" ENSG00000103121 "C-X9-C motif containing 2" Q9NRP2 16 80966448-81020270 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 77.9;Brain excitatory neurons: 95.0;Brain inhibitory neurons: 85.1;Distal convoluted tubule cells: 70.2;Early primary spermatocytes: 71.6;Late primary spermatocytes: 93.4;Late spermatids: 134.9;Oligodendrocyte progenitor cells: 80.9;Oligodendrocytes: 111.4;Other brain neurons: 84.7;Parietal cells: 88.4;Renal collecting duct intercalated cells: 73.3;Renal connecting tubule cells: 76.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "HPA006871, HPA007253, CAB026396" Approved Supported Mitochondria,Cytosol NA Yes "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 98: Neurons - Neurotransmission & signaling" 2 Mitochondria Cytosol "CAB026396: , HPA006871: , HPA007253: " "unprognostic (3.57e-2)" "unprognostic (3.20e-2)" "unprognostic (3.45e-3)" "unprognostic (6.25e-2)" "unprognostic (3.60e-1)" "unprognostic (1.57e-1)" "unprognostic (3.16e-3)" "potential prognostic unfavorable (9.18e-4)" "unprognostic (1.86e-1)" "unprognostic (1.34e-1)" "unprognostic (5.91e-2)" "unprognostic (1.20e-1)" "unprognostic (4.93e-3)" "unprognostic (4.21e-3)" "unprognostic (1.94e-1)" "unprognostic (1.20e-1)" "unprognostic (2.30e-1)" "unprognostic (1.50e-2)" "unprognostic (7.74e-2)" "unprognostic (1.46e-1)" "unprognostic (1.30e-2)" "unprognostic (7.83e-3)" "unprognostic (9.11e-2)" "unprognostic (4.45e-2)" "unprognostic (6.47e-2)" "unprognostic (1.27e-1)" "unprognostic (1.48e-1)" "unprognostic (1.90e-1)" "unprognostic (1.64e-2)" CMC4 "MTCP1, MTCP1NB, p8, P8MTCP1" ENSG00000182712 "C-X9-C motif containing 4" P56277 X 155061622-155071136 "Disease related genes, Predicted intracellular proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric chief cells: 13.1;Oocytes: 18.4;Parietal cells: 19.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045866 Approved Supported Mitochondria NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 52: Non-specific - Cellular respiration" "Cluster 27: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 97: Non-specific - Cellular respiration" 2 Mitochondria "HPA045866: " "unprognostic (6.43e-3)" "unprognostic (1.60e-1)" "unprognostic (1.57e-2)" "unprognostic (1.58e-1)" "unprognostic (5.68e-2)" "unprognostic (2.98e-1)" "unprognostic (9.95e-2)" "unprognostic (5.67e-3)" "unprognostic (7.65e-3)" "unprognostic (3.43e-1)" "unprognostic (2.78e-1)" "unprognostic (6.81e-2)" "unprognostic (6.69e-2)" "unprognostic (1.53e-1)" "unprognostic (4.30e-2)" "unprognostic (3.06e-1)" "unprognostic (6.86e-2)" "unprognostic (1.82e-2)" "unprognostic (1.75e-3)" "unprognostic (6.80e-2)" "unprognostic (2.73e-1)" "unprognostic (3.98e-3)" "unprognostic (8.65e-2)" "unprognostic (4.74e-2)" "unprognostic (1.56e-1)" "unprognostic (6.07e-2)" "unprognostic (1.21e-1)" "unprognostic (2.26e-2)" CMIP ENSG00000153815 "C-Maf inducing protein" Q8IY22 16 81444808-81711762 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 902.4;Platelets: 895.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.0;neutrophil: 2.4" "Lineage enriched" "Detected in single" 4 "granulocytes: 3.0" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells, Pituitary gland - Lactotropes, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054424, HPA066710" Approved Supported Nucleoplasm,Cytosol NA NA 28000 "Cluster 35: Neutrophils - Protein binding" "Cluster 77: Intestine - Digestion" "Cluster 14: Neurons - Synaptic function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 2 "Nucleoplasm, Cytosol" "HPA054424: , HPA066710: " "unprognostic (3.48e-1)" "unprognostic (1.03e-1)" "unprognostic (2.29e-1)" "unprognostic (3.64e-2)" "unprognostic (3.29e-1)" "potential prognostic unfavorable (4.15e-4)" "unprognostic (4.31e-2)" "unprognostic (1.92e-1)" "unprognostic (2.59e-2)" "unprognostic (6.33e-2)" "potential prognostic favorable (2.59e-4)" "unprognostic (1.24e-1)" "unprognostic (3.44e-1)" "unprognostic (2.22e-2)" "unprognostic (4.37e-2)" "potential prognostic unfavorable (2.11e-4)" "unprognostic (7.10e-2)" "unprognostic (1.55e-2)" "unprognostic (2.36e-1)" "unprognostic (2.23e-1)" "unprognostic (7.52e-2)" "unprognostic (4.66e-2)" "unprognostic (2.95e-2)" "unprognostic (8.47e-2)" "unprognostic (3.07e-1)" "unprognostic (2.93e-1)" "unprognostic (1.54e-1)" "unprognostic (2.05e-1)" "unprognostic (1.94e-1)" "potential prognostic unfavorable (3.82e-4)" "unprognostic (3.39e-1)" CMKLR1 RVER1 ENSG00000174600 "Chemerin chemokine-like receptor 1" Q99788 12 108288044-108339317 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 32.3" "Cell type enhanced" "Detected in some" "Fibro-adipogenic progenitors: 24.5;Hofbauer cells: 77.3;Kupffer cells: 233.7;Macrophages: 104.8;Microglia: 98.4;monocytes: 33.9;pDCs: 59.0" "Group enriched" "Detected in some" 5 "central nervous system macrophage: 144.7;fibroblast: 117.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 14.6;plasmacytoid DC: 18.2" "Group enriched" "Detected in many" 22 "dendritic cells: 18.2;monocytes: 14.6;T-cells: 7.1" "Low cancer specificity" "Detected in some" "Adrenal gland - Macrophages, Liver - Kupffer cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047865 Uncertain NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 70: DU4475 - Unknown function" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" "HPA047865: " "unprognostic (2.08e-2)" "unprognostic (2.50e-1)" "unprognostic (1.45e-1)" "unprognostic (1.86e-2)" "unprognostic (1.43e-1)" "unprognostic (1.39e-1)" "unprognostic (6.88e-2)" "unprognostic (1.29e-1)" "unprognostic (1.69e-3)" "unprognostic (1.26e-2)" "unprognostic (1.68e-2)" "unprognostic (6.35e-2)" "unprognostic (5.71e-2)" "unprognostic (3.28e-1)" "unprognostic (5.52e-2)" "unprognostic (8.19e-3)" "unprognostic (2.87e-1)" "unprognostic (4.27e-1)" "unprognostic (3.19e-1)" "unprognostic (1.04e-1)" "unprognostic (2.14e-1)" "unprognostic (9.80e-2)" "unprognostic (1.44e-1)" "unprognostic (1.02e-1)" "unprognostic (1.21e-1)" "unprognostic (1.31e-1)" "unprognostic (1.95e-1)" "unprognostic (3.19e-2)" "unprognostic (3.98e-2)" "unprognostic (1.72e-1)" "unprognostic (2.74e-1)" CMKLR2 GPR1 ENSG00000183671 "Chemerin chemokine-like receptor 2" P46091 2 206175316-206218047 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 31.5" "Cell type enriched" "Detected in some" 23 "Choroid plexus epithelial cells: 236.6" "Cell type enriched" "Detected in many" 5 "choroid plexus epithelial cell: 153.6" "Cancer enhanced" "Detected in some" "Head and Neck Squamous Cell Carcinoma (TCGA): 2.6" "Region enriched" "Detected in many" 12 "choroid plexus: 35.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Colon - Fibroblasts, Kidney - Endothelial cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA010525 Uncertain Supported "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 101: Choroid plexus epithelial cells - Ion transport" "Plasma membrane" "Nucleoplasm, Vesicles" "HPA010525: " "unprognostic (2.85e-2)" "unprognostic (1.16e-1)" "unprognostic (1.58e-2)" "unprognostic (1.01e-1)" "unprognostic (2.02e-3)" "potential prognostic unfavorable (8.87e-4)" CMPK1 "CMPK, UMP-CMPK" ENSG00000162368 "Cytidine/uridine monophosphate kinase 1" P30085 1 47333790-47394866 "Enzymes, Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Pyrimidine biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 830.7;Platelets: 502.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053730, HPA058604" Approved Supported Nucleoplasm "Intracellular and membrane" Enzyme NA NA 1900000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 77: Intestine - Digestion" "Cluster 45: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 3 Nucleoplasm "HPA053730: , HPA058604: " "unprognostic (1.66e-2)" "unprognostic (2.85e-2)" "unprognostic (8.13e-2)" "unprognostic (1.45e-1)" "potential prognostic favorable (4.00e-4)" "unprognostic (1.50e-1)" "unprognostic (3.97e-3)" "unprognostic (3.58e-1)" "unprognostic (9.52e-3)" "unprognostic (1.68e-3)" "potential prognostic favorable (5.04e-6)" "unprognostic (1.02e-1)" "unprognostic (2.83e-2)" "unprognostic (1.70e-3)" "unprognostic (1.46e-1)" "unprognostic (2.14e-1)" "unprognostic (4.19e-2)" "unprognostic (1.89e-1)" "unprognostic (4.14e-2)" "unprognostic (2.40e-1)" "unprognostic (7.29e-2)" "unprognostic (5.00e-2)" "unprognostic (1.65e-2)" "unprognostic (4.90e-1)" "unprognostic (2.82e-2)" "unprognostic (1.83e-2)" "unprognostic (1.37e-1)" "unprognostic (1.08e-2)" "unprognostic (2.10e-1)" "unprognostic (3.85e-3)" "unprognostic (2.65e-1)" CMPK2 "NDK, TYKi, UMP-CMPK2" ENSG00000134326 "Cytidine/uridine monophosphate kinase 2" Q5EBM0 2 6840570-6866635 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Pyrimidine biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 6.1;salivary gland: 8.0" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 20.7;Fallopian tube ciliated cells: 18.6;Foveolar cells: 31.3;Hofbauer cells: 36.6;Kupffer cells: 35.9;Respiratory ciliated cells: 21.6" "Cell type enhanced" "Detected in many" "endothelial cell: 33.9" "Cancer enhanced" "Detected in many" "Stomach Adenocarcinoma (TCGA): 8.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 5.0" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Leukemia: 5.7" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041430, HPA062191" Supported Supported Nucleoplasm,Mitochondria NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" Mitochondria Nucleoplasm "HPA041430: , HPA062191: " "unprognostic (1.64e-1)" "unprognostic (8.43e-2)" "unprognostic (1.99e-1)" "unprognostic (2.41e-2)" "unprognostic (2.69e-1)" "unprognostic (4.73e-2)" "unprognostic (1.80e-1)" "unprognostic (4.00e-2)" "unprognostic (5.53e-2)" "unprognostic (3.96e-3)" "unprognostic (3.13e-1)" "unprognostic (2.97e-2)" "unprognostic (4.31e-2)" "unprognostic (5.71e-2)" "unprognostic (2.46e-2)" "unprognostic (9.14e-2)" "unprognostic (4.05e-1)" "unprognostic (1.11e-1)" "unprognostic (4.63e-2)" "unprognostic (1.31e-1)" "unprognostic (7.06e-2)" "potential prognostic favorable (2.01e-4)" "unprognostic (7.13e-2)" "unprognostic (3.17e-2)" CMSS1 "C3orf26, MGC4308" ENSG00000184220 "Cms1 ribosomal small subunit homolog" Q9BQ75 3 99817837-100181732 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1947.7;Ependymal cells: 1030.2;Epicardial cells: 777.8;Myonuclei: 2411.2" "Cell type enhanced" "Detected in all" "ependymal cell: 1170.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042820 Uncertain Approved "Nucleoplasm,Nuclear membrane,Nucleoli,Mitochondria" NA NA "Cluster 18: Non-specific - Translation" "Cluster 24: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 50: Lymphoma - Unknown function" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 30 Nucleoli "Nucleoplasm, Nuclear membrane, Mitochondria" "HPA042820: " "unprognostic (1.57e-3)" "unprognostic (4.33e-2)" "unprognostic (9.31e-2)" "unprognostic (2.05e-1)" "unprognostic (2.81e-1)" "unprognostic (5.39e-2)" "unprognostic (2.18e-2)" "unprognostic (1.95e-3)" "unprognostic (3.33e-3)" "unprognostic (2.31e-3)" "unprognostic (7.64e-3)" "unprognostic (1.86e-3)" "potential prognostic unfavorable (2.06e-6)" "unprognostic (6.09e-2)" "potential prognostic unfavorable (8.21e-5)" "unprognostic (1.75e-1)" "unprognostic (3.53e-2)" "unprognostic (1.07e-1)" "unprognostic (4.66e-3)" "unprognostic (8.76e-3)" "unprognostic (1.79e-2)" "unprognostic (5.73e-3)" "unprognostic (3.97e-3)" "unprognostic (3.04e-2)" "unprognostic (2.78e-1)" "unprognostic (1.01e-1)" "unprognostic (1.41e-1)" "unprognostic (3.12e-1)" "unprognostic (1.25e-1)" CMTM1 "CKLFH, CKLFH1a, CKLFSF1" ENSG00000089505 "CKLF like MARVEL transmembrane domain containing 1" Q8IZ96 16 66566393-66579137 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "testis: 29.2" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 13.6;Brain inhibitory neurons: 12.2;Early spermatids: 62.3;Late primary spermatocytes: 78.4;Late spermatids: 197.5;Microglia: 29.8;Oligodendrocyte progenitor cells: 17.2;Other brain neurons: 13.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 8.8;eosinophil: 6.2;neutrophil: 7.1" "Lineage enriched" "Detected in many" 5 "granulocytes: 8.8" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "HPA013801, HPA017136" Uncertain Approved Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 23: Testis - Spermatogenesis" "Cluster 6: Non-specific - Immune response" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 22: Non-specific - Basic cellular functions" Nucleoplasm "HPA013801: , HPA017136: " "unprognostic (2.89e-1)" "unprognostic (1.97e-1)" "unprognostic (2.56e-1)" "unprognostic (8.46e-2)" "unprognostic (2.80e-1)" "unprognostic (1.62e-2)" "unprognostic (3.27e-1)" "potential prognostic favorable (1.98e-5)" "unprognostic (2.09e-2)" "unprognostic (1.29e-1)" "unprognostic (2.50e-1)" "unprognostic (1.88e-1)" "unprognostic (1.85e-3)" "potential prognostic unfavorable (5.08e-4)" "unprognostic (2.54e-2)" "unprognostic (1.17e-2)" "unprognostic (5.51e-2)" "unprognostic (3.28e-2)" "unprognostic (1.22e-2)" "unprognostic (1.24e-3)" "unprognostic (3.21e-3)" "unprognostic (6.02e-2)" "unprognostic (2.02e-1)" "unprognostic (6.79e-2)" "unprognostic (2.33e-1)" "unprognostic (1.62e-1)" "unprognostic (7.33e-2)" "unprognostic (1.32e-1)" CMTM2 "CKLFSF2, FLJ25732, MGC39436" ENSG00000140932 "CKLF like MARVEL transmembrane domain containing 2" Q8TAZ6 16 66579448-66588275 "Predicted membrane proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 421 "testis: 616.8" "Cell type enhanced" "Detected in many" "Early spermatids: 3468.8;Late primary spermatocytes: 4321.6;Late spermatids: 3910.0;Neutrophils: 1005.5" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in single" "Testicular Germ Cell Tumor (TCGA): 1.8" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "neutrophil: 1.1" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.1" "Low cancer specificity" "Detected in single" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Lung - Neutrophils_2, Spleen - Neutrophils_2, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 23: Testis - Spermatogenesis" "Cluster 34: Non-specific - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 10 "unprognostic (1.99e-2)" "unprognostic (1.28e-1)" "potential prognostic favorable (4.09e-4)" "unprognostic (1.97e-1)" "unprognostic (1.60e-1)" CMTM3 "BNAS2, CKLFSF3, FLJ31762" ENSG00000140931 "CKLF like MARVEL transmembrane domain containing 3" Q96MX0 16 66603874-66613892 "Predicted intracellular proteins, Predicted membrane proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "cDC: 75.1;Decidual stromal cells: 69.1;Extravillous trophoblasts: 327.3;Hofbauer cells: 130.9;Megakaryocytes: 117.5;pDCs: 82.5" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 30.5;leukocyte: 41.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013870, HPA072695" Approved Approved Nucleoplasm NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 39: Astrocytes - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 19 Nucleoplasm "HPA013870: , HPA072695: " "unprognostic (4.99e-2)" "unprognostic (2.17e-1)" "unprognostic (7.23e-2)" "unprognostic (3.08e-2)" "unprognostic (3.55e-2)" "unprognostic (1.53e-3)" "unprognostic (1.98e-1)" "unprognostic (1.76e-3)" "unprognostic (1.90e-1)" "unprognostic (8.02e-2)" "unprognostic (4.80e-3)" "unprognostic (7.98e-2)" "unprognostic (4.01e-3)" "unprognostic (1.85e-3)" "unprognostic (5.59e-1)" "unprognostic (3.24e-2)" "potential prognostic unfavorable (2.60e-4)" "unprognostic (2.38e-2)" "unprognostic (1.73e-1)" "unprognostic (1.52e-3)" "unprognostic (5.94e-2)" "unprognostic (1.04e-2)" "unprognostic (3.14e-3)" "unprognostic (5.04e-1)" "unprognostic (6.33e-3)" "unprognostic (4.50e-2)" "unprognostic (1.76e-2)" "potential prognostic unfavorable (6.44e-4)" "unprognostic (6.24e-2)" "unprognostic (3.00e-3)" "unprognostic (1.02e-1)" CMTM4 CKLFSF4 ENSG00000183723 "CKLF like MARVEL transmembrane domain containing 4" Q8IZR5 16 66614750-66696743 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 221.0;Distal convoluted tubule cells: 253.2;Foveolar cells: 225.6;Parietal cells: 210.4;Renal collecting duct intercalated cells: 230.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014704, HPA023890" Enhanced Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 33: Thyroid gland - Tissue development" "Cluster 44: Non-specific - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 1 "Golgi apparatus, Vesicles, Plasma membrane" "HPA014704: , HPA023890: " "unprognostic (1.32e-1)" "potential prognostic unfavorable (2.21e-6)" "potential prognostic favorable (3.51e-4)" "unprognostic (1.55e-1)" "unprognostic (8.50e-2)" "potential prognostic favorable (4.69e-4)" "unprognostic (2.03e-1)" "unprognostic (4.47e-2)" "unprognostic (1.75e-2)" "potential prognostic favorable (1.74e-4)" "unprognostic (1.88e-2)" "unprognostic (1.97e-2)" "unprognostic (1.73e-1)" "unprognostic (7.33e-3)" "unprognostic (3.65e-3)" "unprognostic (4.45e-2)" "unprognostic (1.17e-1)" "unprognostic (6.94e-2)" "unprognostic (1.82e-1)" "unprognostic (2.27e-2)" "unprognostic (5.83e-2)" "unprognostic (1.71e-2)" "unprognostic (2.42e-1)" "unprognostic (3.93e-1)" "unprognostic (1.68e-1)" "unprognostic (6.38e-2)" "unprognostic (1.17e-1)" "unprognostic (1.40e-1)" "unprognostic (2.80e-1)" "unprognostic (5.93e-2)" "unprognostic (2.75e-1)" CMTM5 "CKLFSF5, FLJ37521" ENSG00000166091 "CKLF like MARVEL transmembrane domain containing 5" Q96DZ9 14 23376773-23379772 "Predicted membrane proteins, Transporters" Chemotaxis Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 15 "brain: 330.7" "Group enriched" "Detected in some" 14 "Megakaryocytes: 1570.1;Platelets: 2685.0" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 63.2;oligodendrocyte: 204.9" "Group enriched" "Detected in some" 41 "Glioblastoma Multiforme (TCGA): 47.6;Skin Cutaneous Melanoma (TCGA): 21.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "basophil: 20.8" "Lineage enriched" "Detected in many" 19 "granulocytes: 20.8" "Cancer enhanced" "Detected in some" "Leukemia: 7.4;skin cancer: 3.5" "Adipose subcutaneous - Smooth muscle cells, Colon - Enteric glia cells, Kidney - Fibroblasts, Minor Salivary Gland - Fibroblasts, Prostate - Fibroblasts, Skin - Smooth muscle cells, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052338 Enhanced Approved "Golgi apparatus,Vesicles" NA NA 470000 "Cluster 21: Neutrophils - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 47: Leukemia - Hemostasis" "Cluster 47: Platelets - Hemostasis" 40 "Golgi apparatus, Vesicles" "HPA052338: " "unprognostic (1.98e-2)" "unprognostic (2.71e-1)" "unprognostic (3.63e-3)" "unprognostic (2.80e-1)" CMTM6 "CKLFSF6, FLJ20396" ENSG00000091317 "CKLF like MARVEL transmembrane domain containing 6" Q9NX76 3 32481312-32502852 "Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Breast lactating cells: 1034.4;cDC: 508.2;Kupffer cells: 480.7;Megakaryocytes: 488.3;monocytes: 464.1;Neutrophil progenitors: 560.8;Neutrophils: 1208.1;Platelets: 554.6" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 138.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skeletal muscle - Endothelial cells, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026980, HPA063491" Enhanced Approved Vesicles NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 8: Immune cells - Immune response" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 82: Dendritic cells - Antigen presentation" 57 Vesicles "HPA026980: , HPA063491: " "unprognostic (7.31e-3)" "unprognostic (6.54e-2)" "unprognostic (7.44e-2)" "unprognostic (1.16e-1)" "unprognostic (1.93e-1)" "unprognostic (1.35e-1)" "unprognostic (4.89e-2)" "unprognostic (8.61e-3)" "unprognostic (7.33e-2)" "unprognostic (7.64e-2)" "unprognostic (5.81e-3)" "unprognostic (9.86e-2)" "unprognostic (1.53e-1)" "unprognostic (4.80e-2)" "unprognostic (9.18e-2)" "unprognostic (1.44e-1)" "unprognostic (3.97e-3)" "unprognostic (1.76e-1)" "unprognostic (2.42e-2)" "unprognostic (8.99e-2)" "unprognostic (3.90e-2)" "unprognostic (1.25e-3)" "unprognostic (1.55e-1)" "unprognostic (5.37e-2)" "unprognostic (1.02e-1)" "unprognostic (2.20e-1)" "unprognostic (4.28e-2)" "unprognostic (6.26e-2)" "unprognostic (2.72e-1)" "unprognostic (2.00e-1)" "unprognostic (1.91e-1)" CMTM7 "CKLFSF7, FLJ30992" ENSG00000153551 "CKLF like MARVEL transmembrane domain containing 7" Q96FZ5 3 32391698-32483067 "Predicted membrane proteins, Transporters" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast secretory cells: 202.5;cDC: 220.3;Hofbauer cells: 224.6;Kupffer cells: 247.0" "Group enriched" "Detected in all" 4 "central nervous system macrophage: 232.6;leukocyte: 122.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077409 Approved "Plasma membrane" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 39 "Plasma membrane" "HPA077409: " "unprognostic (4.52e-1)" "unprognostic (1.35e-2)" "unprognostic (1.77e-3)" "unprognostic (2.33e-3)" "unprognostic (9.16e-2)" "unprognostic (5.26e-3)" "unprognostic (2.91e-2)" "unprognostic (2.83e-1)" "unprognostic (1.33e-1)" "unprognostic (3.44e-1)" "potential prognostic unfavorable (4.72e-5)" "unprognostic (4.22e-2)" "unprognostic (1.16e-1)" "validated prognostic unfavorable (1.51e-4)" "validated prognostic unfavorable (2.90e-4)" "unprognostic (1.08e-2)" "unprognostic (1.72e-2)" "unprognostic (8.56e-2)" "unprognostic (2.51e-1)" "unprognostic (1.07e-1)" "unprognostic (1.77e-2)" "unprognostic (1.02e-2)" "unprognostic (8.15e-2)" "unprognostic (1.09e-1)" "unprognostic (1.74e-3)" "unprognostic (9.92e-3)" "unprognostic (2.90e-2)" "unprognostic (1.84e-2)" "unprognostic (3.50e-1)" "unprognostic (2.71e-2)" "unprognostic (3.34e-1)" CMTM8 CKLFSF8 ENSG00000170293 "CKLF like MARVEL transmembrane domain containing 8" Q8IZV2 3 32238679-32370321 "Predicted membrane proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 45.0" "Cell type enhanced" "Detected in many" "Breast lactating cells: 383.9;Medullary thymic epithelial cells: 300.0;Pancreatic acinar cells: 262.0;Salivary ionocytes: 351.8" "Cell type enhanced" "Detected in many" "endothelial cell: 300.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 1.6" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Heart muscle - Endothelial cells, Liver - Hepatocytes, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055077, HPA073258" Approved Approved Nucleoplasm NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 47: Endothelial cells - Vasculature" "Cluster 6: Leukemia - Signal transduction" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 9 Nucleoplasm "HPA055077: , HPA073258: " "unprognostic (1.61e-1)" "unprognostic (1.54e-2)" "unprognostic (2.16e-2)" "unprognostic (7.67e-2)" "unprognostic (3.30e-2)" "unprognostic (1.80e-1)" "unprognostic (4.37e-2)" "unprognostic (9.07e-3)" "unprognostic (1.42e-2)" "unprognostic (9.41e-3)" "potential prognostic favorable (1.15e-8)" "unprognostic (1.18e-3)" "potential prognostic unfavorable (7.90e-5)" "unprognostic (5.73e-2)" "unprognostic (1.77e-3)" "unprognostic (2.25e-1)" "unprognostic (3.23e-3)" "unprognostic (3.24e-2)" "unprognostic (1.95e-1)" "unprognostic (2.67e-2)" "unprognostic (3.08e-2)" "unprognostic (1.42e-1)" "unprognostic (5.54e-2)" "unprognostic (3.50e-1)" "unprognostic (3.41e-2)" "unprognostic (5.52e-2)" "unprognostic (3.51e-1)" "unprognostic (8.74e-2)" "unprognostic (1.87e-1)" "unprognostic (1.79e-1)" "unprognostic (2.06e-1)" CMTR1 "FTSJD2, ISG95, KIAA0082, MTr1" ENSG00000137200 "Cap methyltransferase 1" Q8N1G2 6 37433219-37482827 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" "mRNA capping, mRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Sertoli cells: 130.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029954, HPA029979, HPA029980" Enhanced Enhanced Nucleoplasm,Vesicles NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 39: Testis - Nuclear processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 28: Non-specific - Nuclear processes" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 21 Nucleoplasm Vesicles "HPA029954: , HPA029979: , HPA029980: " "unprognostic (2.83e-2)" "unprognostic (1.38e-1)" "unprognostic (2.91e-1)" "unprognostic (5.64e-2)" "unprognostic (2.90e-1)" "unprognostic (1.66e-1)" "unprognostic (2.52e-3)" "unprognostic (1.83e-1)" "unprognostic (4.43e-3)" "potential prognostic favorable (1.49e-4)" "unprognostic (7.92e-3)" "unprognostic (5.66e-2)" "unprognostic (7.91e-3)" "unprognostic (3.30e-2)" "unprognostic (1.52e-1)" "unprognostic (1.25e-1)" "unprognostic (2.05e-2)" "unprognostic (1.36e-1)" "unprognostic (2.66e-1)" "unprognostic (8.45e-3)" "unprognostic (4.58e-2)" "unprognostic (1.24e-1)" "potential prognostic favorable (4.08e-4)" "unprognostic (6.79e-2)" "unprognostic (7.36e-2)" "unprognostic (8.45e-2)" "unprognostic (3.88e-1)" "unprognostic (1.90e-1)" "unprognostic (1.31e-2)" CMTR2 "AFT, FLJ11171, FTSJD1, MTr2" ENSG00000180917 "Cap methyltransferase 2" Q8IYT2 16 71281389-71289715 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "mRNA capping, mRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 22.2;Bergmann glia: 25.9;Choroid plexus epithelial cells: 34.7;Distal convoluted tubule cells: 36.0;Microglia: 54.7;Oligodendrocyte progenitor cells: 22.6;Oligodendrocytes: 24.6;Other brain neurons: 21.1;Podocytes: 20.4;Proximal tubule cells: 24.6;Renal collecting duct intercalated cells: 22.8;Renal connecting tubule cells: 23.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041700, HPA048265" Uncertain Approved "Nuclear speckles,Cell Junctions" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 21: Non-specific - Metabolism" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 15 "Cell Junctions" "Nuclear speckles" "HPA041700: , HPA048265: " "unprognostic (1.73e-1)" "unprognostic (7.06e-2)" "unprognostic (1.69e-2)" "unprognostic (1.42e-1)" "unprognostic (1.80e-1)" "unprognostic (3.77e-1)" "unprognostic (9.79e-2)" "unprognostic (3.94e-2)" "unprognostic (2.44e-1)" "potential prognostic favorable (3.93e-6)" "unprognostic (2.70e-2)" "unprognostic (1.47e-2)" "unprognostic (4.83e-3)" "unprognostic (4.11e-1)" "unprognostic (3.62e-1)" "unprognostic (2.17e-2)" "unprognostic (1.38e-1)" "unprognostic (2.15e-2)" "unprognostic (1.85e-3)" "unprognostic (3.58e-2)" "unprognostic (1.93e-2)" "unprognostic (1.88e-1)" "unprognostic (1.10e-2)" "unprognostic (2.64e-1)" "unprognostic (1.44e-2)" "unprognostic (1.24e-1)" "unprognostic (2.49e-1)" "unprognostic (2.27e-1)" "unprognostic (1.53e-1)" CMYA5 "C5orf10, DKFZp451G223, SPRYD2, TRIM76" ENSG00000164309 "Cardiomyopathy associated 5" Q8N3K9 5 79689836-79800240 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "skeletal muscle: 573.2;tongue: 747.0" "Group enriched" "Detected in many" 4 "Cardiomyocytes: 1720.7;Myonuclei: 3869.4;Thymic myoid cells: 2605.0" "Cell type enhanced" "Detected in all" "Bergmann glia: 182.8;oligodendrocyte precursor cell: 277.7" "Cancer enhanced" "Detected in some" "Head and Neck Squamous Cell Carcinoma (TCGA): 3.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "breast cancer: 1.2" "Adipose visceral - Mesothelial cells, Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Skin - Outer root sheath cells, Stomach - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA058195, HPA077831" Enhanced Uncertain "Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 27: Breast cancer - Unknown function" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 3 "Endoplasmic reticulum, Plasma membrane" "HPA058195: , HPA077831: " "unprognostic (7.68e-2)" "unprognostic (1.66e-1)" "unprognostic (1.30e-2)" "potential prognostic unfavorable (9.42e-7)" "unprognostic (6.62e-2)" "unprognostic (4.52e-3)" "validated prognostic favorable (1.09e-4)" "validated prognostic favorable (4.05e-4)" "unprognostic (2.14e-1)" "unprognostic (2.66e-1)" "unprognostic (1.94e-2)" "unprognostic (1.23e-2)" CNBD1 FLJ35802 ENSG00000176571 "Cyclic nucleotide binding domain containing 1" Q8NA66 8 86866415-87615219 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 14 "testis: 4.7" "Group enriched" "Detected in many" 5 "Early spermatids: 248.9;Late primary spermatocytes: 383.7;Late spermatids: 155.7;Retinal pigment epithelial cells: 375.1" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 23.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA025037, HPA027469, HPA027786" Uncertain NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" "HPA025037: , HPA027469: , HPA027786: " CNBD2 "C20orf152, CNMPD1, dJ954P9.1" ENSG00000149646 "Cyclic nucleotide binding domain containing 2" Q96M20 20 35954564-36030700 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 24.1" "Cell type enhanced" "Detected in many" "Early spermatids: 353.2;Epididymal principal cells: 65.4;Late primary spermatocytes: 153.4;Late spermatids: 146.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA043182 Uncertain Approved "Nucleoli,Actin filaments,Cytosol,Mid piece" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" "Nucleoli, Mid piece" "Actin filaments, Cytosol" "HPA043182: " "unprognostic (1.24e-1)" "unprognostic (1.17e-1)" "unprognostic (1.62e-3)" "unprognostic (5.99e-2)" "unprognostic (1.37e-1)" "unprognostic (2.79e-2)" "unprognostic (3.78e-2)" "unprognostic (2.47e-1)" "unprognostic (1.55e-2)" "unprognostic (6.43e-2)" "unprognostic (4.64e-3)" "unprognostic (7.11e-3)" "unprognostic (5.45e-3)" "unprognostic (4.01e-2)" "unprognostic (4.57e-2)" "unprognostic (2.10e-1)" "unprognostic (4.19e-2)" "potential prognostic favorable (7.53e-4)" "unprognostic (2.44e-2)" "unprognostic (2.63e-1)" "unprognostic (8.48e-3)" "unprognostic (2.08e-1)" "unprognostic (9.36e-2)" "unprognostic (4.13e-2)" "unprognostic (4.97e-2)" "unprognostic (1.33e-1)" "unprognostic (1.77e-1)" CNBP "CNBP1, DM2, RNF163, ZCCHC22, ZNF9" ENSG00000169714 "CCHC-type zinc finger nucleic acid binding protein" P62633 3 129167827-129183922 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Minor Salivary Gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063097 Approved Nucleoplasm,Cytosol NA NA 100000 "Cluster 21: Neutrophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 15: Non-specific - Protein processing" 32 Nucleoplasm Cytosol "HPA063097: " "unprognostic (2.17e-2)" "unprognostic (1.66e-1)" "unprognostic (5.21e-2)" "unprognostic (6.92e-2)" "unprognostic (6.82e-2)" "unprognostic (3.26e-2)" "unprognostic (1.65e-2)" "unprognostic (5.81e-2)" "unprognostic (2.75e-1)" "unprognostic (5.80e-3)" "validated prognostic favorable (6.48e-5)" "validated prognostic favorable (4.94e-4)" "unprognostic (4.04e-2)" "unprognostic (1.10e-3)" "unprognostic (4.65e-3)" "unprognostic (3.12e-2)" "unprognostic (1.45e-2)" "unprognostic (2.07e-1)" "unprognostic (1.26e-1)" "unprognostic (1.24e-1)" "unprognostic (2.29e-2)" "potential prognostic unfavorable (3.10e-4)" "unprognostic (2.02e-1)" "unprognostic (1.50e-2)" "unprognostic (3.65e-2)" "unprognostic (1.61e-1)" "unprognostic (3.29e-2)" "unprognostic (4.77e-2)" "unprognostic (3.67e-1)" "unprognostic (1.60e-1)" "unprognostic (1.81e-2)" CNDP1 "CN1, CPGL2, HsT2308, MGC10825" ENSG00000150656 "Carnosine dipeptidase 1" Q96KN2 18 74534500-74587212 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 56.2" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 739.1" "Group enriched" "Detected in all" 32 "committed oligodendrocyte precursor: 259.7;oligodendrocyte: 905.4" "Cancer enriched" "Detected in some" 4 "Glioblastoma Multiforme (TCGA): 4.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "skin cancer: 1.1" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Sebaceous gland cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA008933, HPA073283" Enhanced "Secreted to blood" Enzyme NA NA 9400000000 2500000000 "Cluster 3: Oligodendrocytes - Myelination" "Cluster 6: Non-specific - Immune response" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 80: Oligodendrocytes - Myelination" 3 "HPA008933: , HPA073283: " "unprognostic (7.01e-2)" "unprognostic (3.73e-1)" "unprognostic (5.24e-3)" "unprognostic (1.21e-1)" CNDP2 "CN2, CPGL, FLJ10830, HsT2298, PEPA" ENSG00000133313 "Carnosine dipeptidase 2" Q96KP4 18 74495816-74523454 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 359.9;Endometrial glandular cells: 328.0;Endometrial luminal cells: 437.9;Enterocytes: 605.8;Hofbauer cells: 319.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Breast glandular cells, Prostate - Prostate glandular cells, Spleen - Macrophages, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026196, HPA036898, HPA036899" Enhanced Enhanced Nucleoplasm,Cytosol NA NA 2200000 "Cluster 13: Non-specific - Mitochondria" "Cluster 72: Kidney - Transmembrane transport" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 10 "Nucleoplasm, Cytosol" "CAB026196: , HPA036898: , HPA036899: " "unprognostic (2.22e-1)" "unprognostic (1.39e-1)" "unprognostic (3.95e-1)" "unprognostic (1.21e-1)" "unprognostic (1.51e-1)" "unprognostic (2.86e-1)" "unprognostic (1.43e-2)" "unprognostic (1.27e-2)" "unprognostic (1.47e-1)" "unprognostic (2.28e-1)" "potential prognostic favorable (1.21e-8)" "unprognostic (2.53e-3)" "potential prognostic favorable (5.10e-9)" "unprognostic (1.07e-2)" "unprognostic (2.62e-1)" "unprognostic (1.34e-1)" "unprognostic (2.64e-2)" "unprognostic (2.01e-3)" "unprognostic (5.37e-2)" "unprognostic (1.27e-1)" "unprognostic (3.02e-1)" "unprognostic (1.15e-3)" "unprognostic (1.01e-1)" "unprognostic (1.61e-1)" "unprognostic (1.97e-1)" "unprognostic (1.73e-2)" "unprognostic (1.47e-1)" "unprognostic (2.17e-2)" "unprognostic (5.10e-3)" "unprognostic (2.71e-1)" "unprognostic (1.46e-1)" CNEP1R1 "C16orf69, FLJ38101, NEP1-R1, TMEM188" ENSG00000205423 "CTD nuclear envelope phosphatase 1 regulatory subunit 1" Q8N9A8 16 50024410-50037088 "Predicted membrane proteins" "Lipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 72.5;Neutrophils: 87.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042815, HPA077906" Uncertain Supported Cytosol NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 31: Non-specific - Transcription" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 24: Neutrophils - Innate immunity signal integration" 2 Cytosol "HPA042815: , HPA077906: " "unprognostic (1.02e-1)" "unprognostic (1.49e-2)" "unprognostic (2.03e-2)" "unprognostic (1.87e-1)" "unprognostic (2.89e-2)" "unprognostic (1.01e-1)" "unprognostic (1.96e-1)" "unprognostic (8.38e-2)" "unprognostic (1.19e-2)" "potential prognostic favorable (1.39e-4)" "unprognostic (2.54e-1)" "unprognostic (6.22e-2)" "unprognostic (6.02e-3)" "unprognostic (1.88e-1)" "unprognostic (5.95e-2)" "unprognostic (5.95e-2)" "unprognostic (3.41e-1)" "unprognostic (1.57e-1)" "potential prognostic unfavorable (1.59e-4)" "unprognostic (4.95e-2)" "unprognostic (1.73e-2)" "unprognostic (6.17e-2)" "unprognostic (3.11e-2)" "unprognostic (1.16e-1)" "unprognostic (4.60e-1)" "unprognostic (8.27e-2)" "unprognostic (7.59e-2)" "unprognostic (3.82e-1)" "unprognostic (3.71e-1)" CNFN PLAC8L2 ENSG00000105427 Cornifelin Q9BYD5 19 42387019-42390297 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 1123.8;esophagus: 2986.1;vagina: 1350.2" "Cell type enriched" "Detected in many" 80 "Esophageal apical cells: 99030.0" "Cell type enhanced" "Detected in many" "endothelial cell: 4.5;hippocampal CA4: 4.7" "Cancer enhanced" "Detected in all" "Head and Neck Squamous Cell Carcinoma (TCGA): 787.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 11 "memory B-cell: 61.4;naive B-cell: 70.6" "Lineage enriched" "Detected in many" 12 "B-cells: 70.6" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular), Spleen - B-cells (Spleen)" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA049073, HPA053997" Enhanced Approved "Microtubules,Cytokinetic bridge" Yes No "Cluster 18: Non-specific - Translation" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 33: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 84: Apical squamous epithelium - Cornification" 10 Microtubules "Cytokinetic bridge" "HPA049073: , HPA053997: " "unprognostic (1.05e-1)" "unprognostic (5.30e-2)" "unprognostic (1.90e-1)" "unprognostic (4.48e-3)" "unprognostic (1.13e-1)" "unprognostic (8.30e-2)" "unprognostic (3.38e-2)" "unprognostic (1.32e-2)" "unprognostic (8.57e-2)" "unprognostic (1.59e-3)" "unprognostic (3.72e-3)" "unprognostic (5.29e-2)" "unprognostic (2.43e-2)" "unprognostic (1.26e-3)" "unprognostic (2.34e-2)" "unprognostic (2.02e-2)" "unprognostic (1.01e-2)" "unprognostic (1.22e-1)" "unprognostic (8.26e-2)" "unprognostic (7.10e-2)" "unprognostic (1.00e-1)" "unprognostic (1.07e-1)" "unprognostic (1.68e-1)" "unprognostic (2.48e-1)" "unprognostic (3.77e-2)" "unprognostic (2.68e-1)" "unprognostic (3.36e-2)" "unprognostic (5.07e-2)" "potential prognostic favorable (3.22e-5)" "unprognostic (4.12e-1)" CNGA1 "CNCG, CNCG1, CNG1, RCNC1, RCNCa, RP49" ENSG00000198515 "Cyclic nucleotide gated channel subunit alpha 1" P29973 4 47935977-48016681 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Sensory transduction, Sodium transport, Transport, Vision" "Calcium channel, Ion channel, Ligand-gated ion channel, Sodium channel" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "retina: 244.8" "Group enriched" "Detected in many" 4 "Esophageal apical cells: 336.9;Rod photoreceptor cells: 1024.5" "Cell type enhanced" "Detected in many" "pericyte: 67.8;vascular associated smooth muscle cell: 38.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes" "Region enhanced" "Detected in single" "basal ganglia: 1.1" "Not detected" "Not detected" HPA076168 Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Mitotic spindle,Primary cilium,Primary cilium tip,Mid piece,Principal piece" Yes NA "Cluster 42: Retina - Visual perception" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 79: Photoreceptor cells - Phototransduction" "Nucleoplasm, Vesicles, Mid piece, Principal piece" "Plasma membrane, Mitotic spindle, Primary cilium, Primary cilium tip" "HPA076168: " "unprognostic (1.03e-1)" "unprognostic (7.73e-2)" "unprognostic (1.14e-1)" "unprognostic (6.01e-3)" "unprognostic (4.58e-2)" "unprognostic (1.79e-1)" "unprognostic (1.59e-2)" "unprognostic (4.25e-2)" "potential prognostic favorable (5.64e-5)" "unprognostic (6.55e-2)" "unprognostic (5.75e-3)" "unprognostic (9.08e-3)" "unprognostic (6.53e-2)" "unprognostic (3.24e-2)" "unprognostic (2.85e-1)" "unprognostic (1.91e-2)" "unprognostic (6.61e-2)" "unprognostic (2.51e-1)" "unprognostic (1.58e-1)" "unprognostic (1.26e-2)" "unprognostic (6.36e-2)" "unprognostic (2.19e-1)" "unprognostic (1.78e-1)" "unprognostic (1.87e-2)" "unprognostic (9.43e-2)" CNGA2 "CNCA, CNCA1, CNG2, FLJ46312, OCNC1, OCNCa, OCNCALPHA" ENSG00000183862 "Cyclic nucleotide gated channel subunit alpha 2" Q16280 X 151734746-151745564 "Predicted membrane proteins, Voltage-gated ion channels" "Calcium transport, Ion transport, Olfaction, Sensory transduction, Transport" "Calcium channel, Calmodulin-binding, Ion channel, Ligand-gated ion channel" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Sertoli cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA015065 Uncertain NA NA "Cluster 11: Neuronal - Sensory perception" "HPA015065: " CNGA3 "ACHM2, CCNC1, CCNCa, CNCG3, CNG3" ENSG00000144191 "Cyclic nucleotide gated channel subunit alpha 3" Q16281 2 98346188-98398601 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Sensory transduction, Sodium transport, Transport, Vision" "Calcium channel, Ion channel, Ligand-gated ion channel, Sodium channel" "Disease variant, Leber congenital amaurosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 4.7;intestine: 5.1;pituitary gland: 10.0;retina: 5.4" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 16.2;Cone photoreceptor cells: 43.5;Early spermatids: 12.1;Lactotrophs: 57.5;Late primary spermatocytes: 14.2;Late spermatids: 11.5;Other brain neurons: 11.5;Somatotrophs: 40.3;Thyrotrophs: 43.1" "Cell type enhanced" "Detected in some" "astrocyte: 11.5;choroid plexus epithelial cell: 10.8;ependymal cell: 10.5" "Cancer enriched" "Detected in some" 6 "Glioblastoma Multiforme (TCGA): 15.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "Neuroblastoma: 1.5" "Colon - Enteric glia cells, Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Early spermatids" "Group enriched" "Detected in some" 6 "basal ganglia: 1.8;hypothalamus: 1.9" "Not detected" "Not detected" "HPA049378, CAB079025" Approved Approved Approved "Mid piece,Principal piece,End piece" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 22: Non-specific - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 1 "Mid piece, Principal piece, End piece" "CAB079025: , HPA049378: " "unprognostic (2.37e-1)" "unprognostic (9.01e-2)" "potential prognostic unfavorable (3.80e-4)" "potential prognostic favorable (4.79e-4)" "unprognostic (1.34e-1)" CNGA4 "CNCA2, CNG5, CNGB2, OCNC2, OCNCb" ENSG00000132259 "Cyclic nucleotide gated channel subunit alpha 4" Q8IV77 11 6234765-6244479 "Predicted membrane proteins, Voltage-gated ion channels" "Calcium transport, Ion transport, Olfaction, Sensory transduction, Transport" "Calcium channel, Ion channel, Ligand-gated ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "fallopian tube: 16.2;testis: 5.9" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 21.5;Cone photoreceptor cells: 16.6;Early spermatids: 20.0;Ependymal cells: 18.9;Epididymal basal cells: 20.3;Erythrocyte progenitors: 18.9;Fallopian tube ciliated cells: 16.5;Late primary spermatocytes: 22.1" "Cell type enhanced" "Detected in many" "ependymal cell: 20.8" "Cancer enriched" "Detected in single" 4 "Uterine Corpus Endometrial Carcinoma (TCGA): 3.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA074128 Uncertain "Nucleoplasm,Plasma membrane" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 65: Non-specific - Cell growth & division" 10 "Nucleoplasm, Plasma membrane" "HPA074128: " "unprognostic (1.42e-1)" "unprognostic (7.55e-2)" CNGB1 "CNCG2, CNCG3L, CNGB1B, GAR1, GARP, RCNC2, RCNCb, RP45" ENSG00000070729 "Cyclic nucleotide gated channel subunit beta 1" Q14028 16 57882340-57971128 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Olfaction, Sensory transduction, Sodium transport, Transport, Vision" "Calcium channel, Ion channel, Ligand-gated ion channel, Sodium channel" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 59 "retina: 557.0" "Group enriched" "Detected in many" 12 "Cone photoreceptor cells: 395.4;Rod photoreceptor cells: 1524.0" "Cell type enhanced" "Detected in many" "amygdala excitatory: 115.6;hippocampal dentate gyrus: 228.9;upper-layer intratelencephalic: 129.5" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 5.2;Kidney Chromophobe (TCGA): 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 11.1" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Ductal cells, Testis - Late spermatids" "Region enhanced" "Detected in some" "hypothalamus: 4.5" HPA060355 Approved "Plasma membrane,Cytosol" No NA "Cluster 42: Retina - Visual perception" "Cluster 14: Neurons - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 79: Photoreceptor cells - Phototransduction" "Plasma membrane, Cytosol" "HPA060355: " "unprognostic (1.32e-2)" "unprognostic (3.14e-2)" "unprognostic (2.66e-1)" "unprognostic (2.15e-1)" "unprognostic (1.36e-3)" "unprognostic (1.55e-1)" "unprognostic (3.41e-2)" "unprognostic (3.82e-1)" "unprognostic (1.95e-1)" "potential prognostic unfavorable (8.66e-4)" CNGB3 "ACHM1, ACHM3, RMCH" ENSG00000170289 "Cyclic nucleotide gated channel subunit beta 3" Q9NQW8 8 86553977-86743675 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sensory transduction, Transport, Vision" "Ion channel, Ligand-gated ion channel" "Disease variant, Stargardt disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 3.9;retina: 11.6" "Group enriched" "Detected in many" 12 "Cardiomyocytes: 297.5;Cone photoreceptor cells: 855.0;Retinal pigment epithelial cells: 771.6" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 29.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pituitary gland - Thyrotropes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA057244 Enhanced NA NA "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 31: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 79: Photoreceptor cells - Phototransduction" "HPA057244: " "unprognostic (1.45e-3)" "unprognostic (5.81e-2)" CNIH1 "CNIH, CNIL, TGAM77" ENSG00000100528 "Cornichon family AMPA receptor auxiliary protein 1" O95406 14 54423561-54441391 "Predicted membrane proteins, Transporters" "ER-Golgi transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002544 Approved Uncertain Vesicles NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 21: Non-specific - Metabolism" "Cluster 3: Rhabdoid - Membrane components" "Cluster 97: Non-specific - Cellular respiration" 21 Vesicles "HPA002544: " "unprognostic (2.46e-1)" "unprognostic (1.17e-2)" "potential prognostic unfavorable (1.13e-4)" "unprognostic (4.87e-3)" "unprognostic (3.79e-2)" "unprognostic (2.85e-1)" "potential prognostic unfavorable (1.31e-4)" "unprognostic (3.85e-3)" "unprognostic (4.06e-2)" "potential prognostic favorable (3.83e-7)" "unprognostic (1.31e-2)" "unprognostic (9.03e-2)" "unprognostic (4.78e-3)" "potential prognostic unfavorable (4.52e-5)" "unprognostic (3.42e-2)" "unprognostic (7.93e-2)" "unprognostic (2.08e-1)" "unprognostic (1.69e-1)" "unprognostic (1.45e-1)" "unprognostic (1.44e-3)" "unprognostic (1.60e-2)" "unprognostic (1.25e-1)" "unprognostic (1.69e-2)" "unprognostic (4.41e-2)" "unprognostic (7.91e-2)" "unprognostic (2.60e-1)" "unprognostic (1.37e-1)" "unprognostic (2.27e-1)" "unprognostic (1.46e-2)" CNIH2 "CNIH-2, Cnil, MGC50896" ENSG00000174871 "Cornichon family AMPA receptor auxiliary protein 2" Q6PI25 11 66278175-66285301 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "brain: 424.2" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 37.0;Brain inhibitory neurons: 32.7;Early spermatids: 82.0;Ependymal cells: 24.7;Late primary spermatocytes: 50.6;Late spermatids: 34.2;Neuroendocrine cells: 24.0;Other brain neurons: 52.0;Pancreatic islet cells: 107.8;Respiratory ciliated cells: 31.8" "Cell type enhanced" "Detected in all" "hippocampal CA4: 130.2" "Cancer enriched" "Detected in many" 6 "Glioblastoma Multiforme (TCGA): 39.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 11.9" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Pancreas - Beta cells, Pituitary gland - Lactotropes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 29: Forebrain - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 5 "unprognostic (1.34e-1)" "unprognostic (9.21e-3)" "unprognostic (4.01e-2)" "potential prognostic favorable (1.43e-4)" "unprognostic (1.77e-1)" "unprognostic (1.20e-3)" "unprognostic (1.54e-1)" "unprognostic (6.21e-2)" "unprognostic (8.90e-2)" "unprognostic (4.10e-2)" "unprognostic (4.76e-2)" "unprognostic (1.22e-2)" "potential prognostic favorable (5.26e-4)" "unprognostic (1.56e-2)" "unprognostic (4.34e-1)" "unprognostic (8.63e-2)" "unprognostic (6.19e-3)" CNIH3 "CNIH-3, FLJ38993" ENSG00000143786 "Cornichon family AMPA receptor auxiliary protein 3" Q8TBE1 1 224434660-224740554 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 10.9;pancreas: 7.4" "Cell type enhanced" "Detected in many" "Bergmann glia: 110.5;Late spermatids: 116.6;Pituicytes/FSCs: 117.8;Podocytes: 112.0" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Glioblastoma Multiforme (TCGA): 20.5;Skin Cutaneous Melanoma (TCGA): 25.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 18.5;thyroid cancer: 18.4" "Colon - Enteric glia cells, Prostate - Fibroblasts, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 23 "unprognostic (5.82e-2)" "unprognostic (1.74e-1)" "unprognostic (6.30e-2)" "unprognostic (5.73e-2)" "unprognostic (2.61e-1)" "unprognostic (2.70e-1)" "unprognostic (1.94e-2)" "unprognostic (2.46e-2)" "unprognostic (1.07e-1)" "unprognostic (2.45e-1)" "unprognostic (4.65e-2)" "potential prognostic unfavorable (1.04e-4)" "unprognostic (1.25e-1)" "unprognostic (1.81e-1)" "unprognostic (1.02e-1)" "unprognostic (1.96e-2)" "unprognostic (1.68e-1)" "unprognostic (7.71e-2)" "unprognostic (1.53e-1)" "unprognostic (6.05e-3)" "unprognostic (1.64e-1)" "unprognostic (2.31e-1)" "unprognostic (9.75e-2)" "unprognostic (2.07e-2)" CNIH4 HSPC163 ENSG00000143771 "Cornichon family AMPA receptor auxiliary protein 4" Q9P003 1 224356858-224379459 "Predicted membrane proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 311.3;Esophageal suprabasal cells: 278.5;Gastric progenitor cells: 448.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044268 Approved NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 6 "HPA044268: " "unprognostic (2.17e-1)" "unprognostic (6.50e-2)" "unprognostic (2.37e-1)" "unprognostic (8.91e-3)" "unprognostic (2.23e-2)" "unprognostic (6.10e-2)" "unprognostic (6.20e-2)" "unprognostic (1.34e-1)" "potential prognostic unfavorable (2.21e-4)" "unprognostic (2.86e-1)" "unprognostic (1.10e-2)" "unprognostic (1.50e-3)" "unprognostic (2.20e-3)" "unprognostic (1.48e-2)" "unprognostic (5.67e-3)" "unprognostic (7.68e-2)" "unprognostic (6.07e-2)" "unprognostic (8.92e-3)" "unprognostic (1.22e-1)" "unprognostic (7.87e-2)" "unprognostic (4.11e-2)" "unprognostic (1.43e-3)" "unprognostic (3.09e-3)" "unprognostic (6.90e-3)" "unprognostic (3.25e-1)" "unprognostic (6.02e-2)" "unprognostic (8.35e-2)" "unprognostic (3.35e-3)" "unprognostic (3.40e-1)" "unprognostic (1.86e-1)" "unprognostic (3.56e-2)" CNKSR1 "CNK, CNK1, KSR" ENSG00000142675 "Connector enhancer of kinase suppressor of Ras 1" Q969H4 1 26177484-26189884 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 53.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 67.2;Enterocytes: 62.0;Esophageal apical cells: 106.2;Ocular epithelial cells: 60.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Lung - Alveolar cells type 2, Prostate - Prostate basal glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA030847 Uncertain Approved Cytosol NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 15: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 19 Cytosol "HPA030847: " "unprognostic (4.14e-2)" "unprognostic (1.46e-1)" "unprognostic (9.35e-2)" "unprognostic (5.48e-2)" "unprognostic (5.42e-2)" "unprognostic (1.48e-1)" "potential prognostic favorable (8.87e-5)" "unprognostic (9.83e-2)" "unprognostic (2.83e-2)" "unprognostic (2.09e-1)" "unprognostic (2.29e-1)" "unprognostic (1.79e-1)" "unprognostic (1.72e-1)" "unprognostic (9.23e-2)" "unprognostic (8.78e-2)" "unprognostic (2.56e-1)" "unprognostic (9.98e-2)" "unprognostic (2.55e-1)" "unprognostic (4.91e-1)" "unprognostic (6.62e-2)" "unprognostic (1.41e-3)" "unprognostic (4.07e-2)" "unprognostic (2.73e-2)" "unprognostic (9.10e-2)" "unprognostic (3.74e-2)" "unprognostic (1.55e-2)" "unprognostic (2.32e-1)" "unprognostic (2.18e-1)" CNKSR2 "CNK2, KIAA0902, KSR2" ENSG00000149970 "Connector enhancer of kinase suppressor of Ras 2" Q8WXI2 X 21372801-21654695 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 35.0;retina: 16.6" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 457.4;Astrocytes: 217.8;Brain excitatory neurons: 717.2;Brain inhibitory neurons: 405.4;Cone photoreceptor cells: 194.6;Retinal amacrine cells: 504.2;Retinal horizontal cells: 176.3;Rod photoreceptor cells: 729.9" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Glioblastoma Multiforme (TCGA): 3.9;Prostate Adenocarcinoma (TCGA): 1.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Lung - Fibroblasts_1, Spleen - B-cells (Spleen), Testis - Spermatogonia, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001502 Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 27: Cerebellum - Synaptic function" "Cluster 34: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 35: Neurons - Synaptic function & neurogenesis" 6 "Golgi apparatus, Plasma membrane" "HPA001502: " "unprognostic (1.59e-2)" "unprognostic (7.87e-2)" "unprognostic (2.27e-2)" "unprognostic (2.11e-2)" "unprognostic (1.34e-1)" "unprognostic (1.70e-1)" CNKSR3 "FLJ31349, MAGI1" ENSG00000153721 "CNKSR family member 3" Q6P9H4 6 154387515-154510685 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 264.7;Loop of henle epithelial cells: 258.7;Papillary tip epithelial cells: 79.3;Podocytes: 262.0;Proximal tubule cells: 559.3;Renal collecting duct intercalated cells: 150.6;Renal collecting duct principal cells: 93.1;Renal connecting tubule cells: 281.9" "Cell type enhanced" "Detected in single" "choroid plexus epithelial cell: 2.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skin - Outer root sheath cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037133, HPA049651" Approved Supported Mitochondria,Cytosol NA NA "Cluster 60: Stomach - Digestion" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 88: Proximal tubular cells - Transmembrane transport" 21 Cytosol Mitochondria "CAB037133: , HPA049651: " "unprognostic (4.44e-2)" "unprognostic (1.20e-1)" "unprognostic (9.71e-2)" "unprognostic (9.83e-3)" "unprognostic (2.96e-1)" "unprognostic (6.61e-2)" "unprognostic (1.08e-1)" "potential prognostic favorable (8.98e-4)" "unprognostic (2.39e-2)" "unprognostic (5.76e-2)" "potential prognostic favorable (1.08e-9)" "unprognostic (6.02e-3)" "unprognostic (2.16e-1)" "unprognostic (1.76e-1)" "unprognostic (3.19e-1)" "unprognostic (2.96e-1)" "unprognostic (1.93e-1)" "unprognostic (1.71e-1)" "unprognostic (6.57e-2)" "unprognostic (5.10e-2)" "unprognostic (6.93e-3)" "unprognostic (5.83e-2)" "unprognostic (4.86e-2)" "unprognostic (3.20e-1)" "unprognostic (1.13e-2)" "potential prognostic favorable (1.46e-4)" "unprognostic (4.45e-2)" "unprognostic (4.31e-2)" "unprognostic (2.14e-1)" "unprognostic (1.39e-2)" "unprognostic (1.84e-1)" CNMD "BRICD3, CHM-I, CHM1, LECT1, MYETS1" ENSG00000136110 Chondromodulin O75829 13 52703264-52739820 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 6.4;choroid plexus: 11.9;retina: 7.7;salivary gland: 6.3;thyroid gland: 3.1" "Cell type enriched" "Detected in many" 4 "Müller glia: 108.5" "Cell type enhanced" "Detected in many" "oligodendrocyte precursor cell: 22.4" "Group enriched" "Detected in some" 4 "Lung Adenocarcinoma (TCGA): 18.4;Testicular Germ Cell Tumor (TCGA): 8.9;Thyroid Carcinoma (TCGA): 7.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 1.1;testis cancer: 1.2" "Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Beta cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010510 Uncertain "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 33: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 11: Muller glia cells - Retinal homeostasis" "HPA010510: " "unprognostic (3.52e-2)" "unprognostic (1.65e-3)" "unprognostic (1.61e-2)" "unprognostic (3.12e-3)" "unprognostic (1.09e-2)" "unprognostic (2.65e-1)" "unprognostic (4.04e-1)" "unprognostic (2.41e-1)" CNN1 "Sm-Calp, SMCC" ENSG00000130176 "Calponin 1" P51911 19 11538767-11550323 "Cancer-related genes, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 2087.4;intestine: 2743.0;smooth muscle: 2059.2" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 837.0;Decidual stromal cells: 451.4;Early spermatids: 449.9;Late spermatids: 741.2;Peritubular myoid cells: 185.1;Salivary myoepithelial cells: 277.5;Smooth muscle cells: 2790.8;Vascular smooth muscle cells: 526.4" "Cell type enriched" "Detected in some" 104 "vascular associated smooth muscle cell: 146.9" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 406.5;Stomach Adenocarcinoma (TCGA): 341.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 58.4;testis cancer: 66.8" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Adrenal gland - Smooth muscle cells, Breast - Breast myoepithelial cells, Colon - Smooth muscle cells, Lung - Smooth muscle cells, Minor Salivary Gland - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Skin - Smooth muscle cells, Spleen - Smooth muscle cells, Testis - Late spermatids, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB000007, HPA014263" Enhanced Approved "Actin filaments" No No 51000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 7 "Actin filaments" "CAB000007: , HPA014263: " "potential prognostic favorable (9.62e-4)" "unprognostic (2.22e-3)" "unprognostic (1.47e-1)" "unprognostic (2.23e-1)" "unprognostic (2.47e-2)" "unprognostic (5.54e-2)" "unprognostic (2.28e-1)" "unprognostic (3.51e-3)" "unprognostic (1.91e-1)" "unprognostic (1.76e-1)" "unprognostic (2.32e-2)" "unprognostic (3.07e-2)" "potential prognostic unfavorable (5.88e-7)" "unprognostic (7.70e-3)" "unprognostic (3.47e-1)" "unprognostic (8.94e-2)" "unprognostic (1.01e-1)" "unprognostic (6.66e-3)" "unprognostic (4.27e-2)" "unprognostic (1.23e-2)" "unprognostic (1.86e-2)" "unprognostic (2.35e-1)" "unprognostic (7.64e-2)" "unprognostic (1.49e-1)" "unprognostic (9.99e-3)" "unprognostic (2.67e-2)" "unprognostic (4.94e-3)" "unprognostic (8.96e-3)" "unprognostic (2.58e-1)" "unprognostic (1.83e-3)" "unprognostic (6.31e-2)" CNN2 ENSG00000064666 "Calponin 2" Q99439 19 1026586-1039068 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 327.7;Megakaryocytes: 476.0;Neutrophil progenitors: 286.2;Neutrophils: 590.0" "Group enriched" "Detected in some" 4 "fibroblast: 20.7;leukocyte: 55.9;pericyte: 17.1;vascular associated smooth muscle cell: 47.6" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "choroid plexus: 54.0" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049095, HPA075297" Approved Approved "Actin filaments" NA NA 7300000 "Cluster 21: Neutrophils - Unknown function" "Cluster 54: Non-specific - Ribosome" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 55: Lymphoma - Immune response" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 5 "Actin filaments" "HPA049095: , HPA075297: " "unprognostic (5.37e-2)" "unprognostic (6.02e-3)" "unprognostic (1.42e-1)" "unprognostic (7.75e-2)" "unprognostic (9.18e-2)" "unprognostic (3.64e-1)" "unprognostic (6.02e-1)" "unprognostic (2.01e-2)" "unprognostic (1.41e-1)" "unprognostic (1.73e-1)" "unprognostic (4.60e-3)" "unprognostic (1.58e-1)" "unprognostic (7.21e-3)" "unprognostic (1.51e-1)" "unprognostic (6.11e-2)" "unprognostic (1.82e-1)" "unprognostic (1.17e-1)" "unprognostic (1.73e-1)" "unprognostic (1.28e-1)" "unprognostic (2.12e-2)" "unprognostic (3.58e-2)" "unprognostic (2.45e-2)" "unprognostic (1.11e-1)" "unprognostic (1.09e-2)" "unprognostic (1.42e-1)" "unprognostic (5.03e-2)" "unprognostic (1.67e-1)" "unprognostic (4.39e-2)" "unprognostic (2.84e-1)" "unprognostic (1.55e-1)" "unprognostic (2.31e-1)" CNN3 ENSG00000117519 "Calponin 3" Q15417 1 94896949-94927223 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 1917.6;Hepatic stellate cells: 522.8;Schwann cells: 521.6" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 735.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 10.6;naive CD4 T-cell: 11.6" "Group enriched" "Detected in many" 12 "B-cells: 10.6;T-cells: 11.6" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Kidney - Endothelial cells, Pituitary gland - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009849, HPA051237" Enhanced Enhanced "Actin filaments,Cytosol" NA NA 640000 "Cluster 24: Non-specific - Transcription" "Cluster 75: Ovary - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 84: Apical squamous epithelium - Cornification" 11 "Actin filaments" Cytosol "CAB009849: , HPA051237: " "unprognostic (2.46e-1)" "unprognostic (1.38e-1)" "unprognostic (1.40e-1)" "unprognostic (2.78e-3)" "unprognostic (1.45e-1)" "unprognostic (5.46e-1)" "unprognostic (1.35e-1)" "unprognostic (3.13e-2)" "unprognostic (9.03e-2)" "unprognostic (1.46e-1)" "potential prognostic favorable (1.94e-8)" "unprognostic (4.02e-3)" "unprognostic (1.05e-1)" "unprognostic (3.49e-2)" "unprognostic (1.94e-1)" "unprognostic (8.82e-2)" "unprognostic (4.77e-3)" "unprognostic (2.23e-1)" "unprognostic (9.01e-2)" "unprognostic (9.82e-2)" "unprognostic (8.38e-3)" "unprognostic (1.98e-1)" "unprognostic (2.64e-1)" "unprognostic (3.38e-1)" "unprognostic (1.49e-1)" "unprognostic (6.01e-2)" "unprognostic (2.79e-1)" "unprognostic (6.44e-3)" "unprognostic (7.86e-2)" "unprognostic (9.14e-2)" "unprognostic (2.32e-1)" CNNM1 ACDP1 ENSG00000119946 "Cyclin and CBS domain divalent metal cation transport mediator 1" Q9NRU3 10 99329356-99394330 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 13.2;testis: 9.8" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 53.2;Brain excitatory neurons: 62.8;Brain inhibitory neurons: 97.6;Early spermatids: 182.1;Late primary spermatocytes: 50.2;Late spermatids: 151.8;Other brain neurons: 53.4;Retinal amacrine cells: 52.7;Retinal bipolar cells: 42.6;Retinal ganglion cells: 46.4;Retinal horizontal cells: 84.1;Sertoli cells: 160.2;Thyrotrophs: 64.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040408 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 7: Liver cancer - Metabolism" "Cluster 35: Neurons - Synaptic function & neurogenesis" 8 "Plasma membrane, Cytosol" "HPA040408: " "unprognostic (2.74e-2)" "unprognostic (3.52e-2)" "unprognostic (6.13e-2)" "unprognostic (1.30e-1)" "unprognostic (2.60e-2)" "unprognostic (1.86e-1)" "unprognostic (6.66e-2)" "unprognostic (2.30e-2)" "unprognostic (4.53e-2)" "unprognostic (7.53e-2)" "unprognostic (2.09e-3)" "unprognostic (1.91e-1)" "unprognostic (2.32e-1)" "unprognostic (2.06e-1)" "unprognostic (1.91e-1)" CNNM2 ACDP2 ENSG00000148842 "Cyclin and CBS domain divalent metal cation transport mediator 2" Q9H8M5 10 102918294-103090222 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Disease variant, Epilepsy, Intellectual disability, Primary hypomagnesemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 22.2;parathyroid gland: 29.6" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 1054.7;Distal convoluted tubule cells: 1824.0;Syncytiotrophoblasts: 379.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "NK-cell: 1.5" "Lineage enriched" "Detected in single" 4 "NK-cells: 1.5" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Fibroblasts, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059954, HPA071631" Approved Vesicles NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 5: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 2 Vesicles "HPA059954: , HPA071631: " "unprognostic (1.03e-1)" "unprognostic (1.46e-1)" "unprognostic (2.46e-2)" "unprognostic (1.04e-1)" "unprognostic (7.80e-3)" "unprognostic (6.64e-3)" "unprognostic (3.43e-1)" "potential prognostic favorable (2.62e-4)" "unprognostic (2.59e-1)" "unprognostic (2.21e-1)" "potential prognostic favorable (6.68e-9)" "unprognostic (1.28e-3)" "unprognostic (4.47e-1)" "unprognostic (1.39e-1)" "unprognostic (6.07e-3)" "unprognostic (7.91e-2)" "unprognostic (3.05e-1)" "unprognostic (1.27e-2)" "unprognostic (1.11e-2)" "unprognostic (2.75e-2)" "unprognostic (6.40e-2)" "unprognostic (4.65e-2)" "unprognostic (3.35e-2)" "unprognostic (1.66e-1)" "unprognostic (3.78e-2)" "unprognostic (2.64e-1)" "potential prognostic favorable (7.96e-4)" "unprognostic (3.09e-1)" "unprognostic (4.58e-1)" "unprognostic (4.68e-3)" "unprognostic (2.81e-1)" CNNM3 ACDP3 ENSG00000168763 "Cyclin and CBS domain divalent metal cation transport mediator 3" Q8NE01 2 96816245-96835382 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016711 Supported Approved Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 25: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 17: Non-specific - RNA processing" 78 Cytosol "HPA016711: " "unprognostic (1.06e-2)" "unprognostic (1.03e-2)" "unprognostic (4.27e-1)" "unprognostic (2.13e-1)" "unprognostic (8.60e-2)" "unprognostic (6.67e-2)" "unprognostic (1.69e-1)" "unprognostic (9.91e-2)" "unprognostic (1.26e-1)" "unprognostic (1.37e-1)" "validated prognostic favorable (5.18e-9)" "validated prognostic favorable (3.55e-7)" "unprognostic (8.71e-2)" "unprognostic (1.03e-1)" "unprognostic (1.54e-1)" "unprognostic (1.69e-1)" "unprognostic (8.07e-2)" "unprognostic (3.54e-3)" "unprognostic (1.25e-2)" "unprognostic (9.20e-2)" "unprognostic (3.48e-1)" "unprognostic (4.23e-2)" "unprognostic (5.50e-3)" "unprognostic (2.24e-1)" "unprognostic (9.98e-2)" "unprognostic (3.76e-2)" "unprognostic (4.08e-1)" "unprognostic (2.34e-1)" "unprognostic (3.58e-1)" "unprognostic (1.35e-1)" "unprognostic (7.55e-2)" CNNM4 "ACDP4, KIAA1592" ENSG00000158158 "Cyclin and CBS domain divalent metal cation transport mediator 4" Q6P4Q7 2 96760902-96811874 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Biomineralization, Ion transport, Sensory transduction, Transport, Vision" "Amelogenesis imperfecta, Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 36.0" "Cell type enhanced" "Detected in many" "Colonocytes: 143.2;Cone photoreceptor cells: 186.3;Rod photoreceptor cells: 129.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 1, Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Skeletal myocytes, Stomach - Gastric mucous cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017732 Enhanced Uncertain "Plasma membrane,Actin filaments" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 15: Non-specific - Transcription" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 79: Photoreceptor cells - Phototransduction" 29 "Actin filaments" "Plasma membrane" "HPA017732: " "unprognostic (4.69e-2)" "unprognostic (2.13e-3)" "unprognostic (1.09e-1)" "unprognostic (1.17e-2)" "unprognostic (3.77e-1)" "unprognostic (1.90e-3)" "unprognostic (4.82e-2)" "unprognostic (3.07e-1)" "unprognostic (2.74e-2)" "potential prognostic unfavorable (6.12e-4)" "unprognostic (3.41e-2)" "unprognostic (2.73e-1)" "unprognostic (1.27e-1)" "unprognostic (3.57e-3)" "unprognostic (1.48e-2)" "unprognostic (3.23e-2)" "potential prognostic unfavorable (7.27e-4)" "unprognostic (7.09e-3)" "unprognostic (2.40e-2)" "potential prognostic unfavorable (4.80e-4)" "unprognostic (1.08e-1)" "unprognostic (8.18e-3)" "unprognostic (1.17e-1)" "unprognostic (2.60e-1)" "potential prognostic favorable (9.58e-4)" "unprognostic (3.88e-1)" "unprognostic (3.10e-1)" "unprognostic (1.11e-1)" "unprognostic (1.23e-1)" "unprognostic (4.03e-3)" "unprognostic (1.56e-1)" CNOT1 "AD-005, CDC39, KIAA1007, NOT1, NOT1H" ENSG00000125107 "CCR4-NOT transcription complex subunit 1" A5YKK6 16 58519951-58629885 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "RNA-mediated gene silencing, Transcription, Transcription regulation, Translation regulation" "Developmental protein, Repressor" "Autism spectrum disorder, Disease variant, Holoprosencephaly, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029844, HPA046577, HPA049664" Approved Uncertain Cytosol NA NA 3400 "Cluster 33: Non-specific - ATP binding" "Cluster 39: Testis - Nuclear processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 17: Non-specific - RNA processing" 71 Cytosol "HPA029844: , HPA046577: , HPA049664: " "unprognostic (1.89e-1)" "unprognostic (5.51e-2)" "unprognostic (1.69e-1)" "unprognostic (6.76e-3)" "unprognostic (2.86e-2)" "unprognostic (2.77e-2)" "unprognostic (1.96e-1)" "unprognostic (5.62e-3)" "unprognostic (1.42e-1)" "unprognostic (1.74e-2)" "potential prognostic favorable (1.19e-6)" "unprognostic (1.02e-2)" "unprognostic (6.09e-2)" "unprognostic (3.01e-2)" "unprognostic (1.30e-2)" "unprognostic (1.85e-1)" "unprognostic (5.17e-3)" "unprognostic (1.41e-1)" "unprognostic (2.93e-1)" "unprognostic (3.69e-2)" "unprognostic (2.19e-1)" "unprognostic (3.52e-3)" "potential prognostic unfavorable (2.75e-4)" "unprognostic (1.14e-1)" "unprognostic (3.30e-2)" "unprognostic (2.34e-1)" "unprognostic (3.27e-2)" "unprognostic (3.05e-1)" "unprognostic (1.67e-1)" "unprognostic (2.68e-2)" "unprognostic (2.01e-1)" CNOT10 "FLJ12890, FLJ13165" ENSG00000182973 "CCR4-NOT transcription complex subunit 10" Q9H9A5 3 32685145-32773875 "Predicted intracellular proteins" "RNA-mediated gene silencing, Transcription, Transcription regulation, Translation regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035614, HPA041450" Approved Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 39: Testis - Nuclear processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 34: Testis cancer - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 26 "Nucleoplasm, Centrosome" Cytosol "HPA035614: , HPA041450: " "unprognostic (8.60e-3)" "unprognostic (5.15e-2)" "unprognostic (4.66e-3)" "unprognostic (3.17e-1)" "unprognostic (2.76e-2)" "unprognostic (2.06e-1)" "unprognostic (2.06e-2)" "unprognostic (1.20e-1)" "unprognostic (1.97e-1)" "unprognostic (8.48e-3)" "potential prognostic favorable (1.11e-4)" "unprognostic (1.23e-2)" "unprognostic (1.03e-2)" "validated prognostic unfavorable (2.65e-6)" "validated prognostic unfavorable (7.43e-4)" "unprognostic (3.45e-2)" "unprognostic (6.50e-3)" "unprognostic (1.21e-1)" "unprognostic (1.63e-1)" "unprognostic (1.92e-1)" "unprognostic (1.79e-1)" "unprognostic (3.91e-2)" "unprognostic (3.64e-2)" "unprognostic (4.18e-2)" "potential prognostic favorable (5.57e-4)" "unprognostic (3.14e-1)" "unprognostic (8.86e-2)" "unprognostic (1.73e-1)" "unprognostic (1.38e-1)" "unprognostic (1.18e-1)" "unprognostic (9.65e-2)" CNOT11 "C2orf29, C40" ENSG00000158435 "CCR4-NOT transcription complex subunit 11" Q9UKZ1 2 101252886-101270316 "Predicted intracellular proteins" "RNA-mediated gene silencing, Transcription, Transcription regulation, Translation regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069823, HPA074943" Enhanced Approved Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 52: Non-specific - Cellular respiration" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 58 Nucleoplasm "HPA069823: , HPA074943: " "unprognostic (4.82e-3)" "unprognostic (9.31e-2)" "unprognostic (8.17e-2)" "unprognostic (7.95e-2)" "unprognostic (1.03e-1)" "unprognostic (2.28e-1)" "unprognostic (3.19e-1)" "unprognostic (2.94e-3)" "unprognostic (1.51e-3)" "unprognostic (2.81e-1)" "unprognostic (1.92e-1)" "unprognostic (1.82e-2)" "potential prognostic unfavorable (1.08e-6)" "unprognostic (6.69e-2)" "unprognostic (8.07e-2)" "unprognostic (1.20e-1)" "unprognostic (1.67e-1)" "unprognostic (1.31e-1)" "unprognostic (1.79e-1)" "unprognostic (6.90e-2)" "unprognostic (2.23e-1)" "unprognostic (2.83e-2)" "unprognostic (8.90e-2)" "unprognostic (1.88e-2)" "unprognostic (1.04e-2)" "unprognostic (2.45e-1)" "unprognostic (3.17e-1)" "unprognostic (1.06e-1)" "unprognostic (5.57e-2)" CNOT2 "CDC36, NOT2, NOT2H" ENSG00000111596 "CCR4-NOT transcription complex subunit 2" Q9NZN8 12 70243002-70354993 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "RNA-mediated gene silencing, Transcription, Transcription regulation, Translation regulation" "Developmental protein, Repressor" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067711 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 49: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 79 Nucleoplasm Cytosol "HPA067711: " "unprognostic (2.25e-1)" "unprognostic (5.95e-2)" "unprognostic (5.89e-2)" "unprognostic (1.78e-1)" "unprognostic (1.07e-1)" "unprognostic (1.35e-1)" "unprognostic (2.62e-1)" "unprognostic (1.75e-2)" "unprognostic (1.15e-1)" "potential prognostic unfavorable (1.97e-4)" "potential prognostic favorable (9.68e-4)" "unprognostic (3.67e-3)" "unprognostic (1.56e-1)" "potential prognostic unfavorable (3.72e-4)" "unprognostic (1.27e-1)" "unprognostic (1.72e-2)" "unprognostic (4.30e-2)" "unprognostic (2.22e-2)" "unprognostic (2.35e-1)" "unprognostic (8.13e-2)" "unprognostic (2.30e-1)" "unprognostic (1.81e-2)" "potential prognostic unfavorable (3.67e-4)" "unprognostic (6.57e-2)" "unprognostic (1.62e-1)" "unprognostic (1.15e-1)" "unprognostic (2.86e-2)" "unprognostic (7.87e-2)" "unprognostic (4.62e-1)" "unprognostic (1.46e-1)" "unprognostic (2.63e-1)" CNOT3 "KIAA0691, LENG2, NOT3, NOT3H" ENSG00000088038 "CCR4-NOT transcription complex subunit 3" O75175 19 54137749-54155681 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "RNA-mediated gene silencing, Transcription, Transcription regulation, Translation regulation" "Developmental protein, Repressor" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Tuft cells: 34.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006408 Approved Approved Cytosol NA NA 90000 "Cluster 29: Non-specific - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 4: Non-specific - Transcription" "Cluster 102: Non-specific - Mixed function" 63 Cytosol "HPA006408: " "unprognostic (8.79e-3)" "unprognostic (1.78e-1)" "unprognostic (2.74e-2)" "potential prognostic unfavorable (8.13e-4)" "unprognostic (1.08e-1)" "potential prognostic unfavorable (1.08e-4)" "unprognostic (1.64e-1)" "unprognostic (1.52e-1)" "unprognostic (4.96e-1)" "unprognostic (1.80e-1)" "unprognostic (8.11e-3)" "unprognostic (1.26e-2)" "unprognostic (9.50e-2)" "potential prognostic unfavorable (9.45e-5)" "unprognostic (1.25e-1)" "unprognostic (5.57e-2)" "unprognostic (9.39e-2)" "unprognostic (1.37e-1)" "unprognostic (1.64e-2)" "unprognostic (3.47e-2)" "unprognostic (8.66e-2)" "unprognostic (1.15e-1)" "unprognostic (7.98e-3)" "unprognostic (1.78e-2)" "unprognostic (6.18e-2)" "unprognostic (1.75e-1)" "unprognostic (7.24e-3)" "unprognostic (7.75e-2)" "unprognostic (2.11e-1)" "unprognostic (6.78e-2)" "unprognostic (1.28e-1)" CNOT4 "CLONE243, NOT4, NOT4H" ENSG00000080802 "CCR4-NOT transcription complex subunit 4" O95628 7 135361795-135510145 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Transcription factors" "Ubl conjugation pathway" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Sertoli cells: 484.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005737 Approved NA NA "Cluster 32: Basophils - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 16: Non-specific - Transcription" "Cluster 39: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 10 "HPA005737: " "unprognostic (1.45e-1)" "unprognostic (4.27e-2)" "unprognostic (2.74e-1)" "potential prognostic unfavorable (6.95e-5)" "unprognostic (1.86e-2)" "unprognostic (3.12e-3)" "unprognostic (2.95e-1)" "unprognostic (2.04e-1)" "unprognostic (1.34e-2)" "potential prognostic unfavorable (3.11e-4)" "potential prognostic favorable (1.28e-6)" "unprognostic (1.51e-3)" "unprognostic (5.11e-2)" "potential prognostic unfavorable (1.70e-4)" "unprognostic (1.91e-1)" "unprognostic (6.42e-2)" "unprognostic (8.60e-2)" "unprognostic (1.04e-1)" "unprognostic (1.28e-1)" "unprognostic (1.23e-1)" "unprognostic (1.14e-2)" "unprognostic (3.13e-1)" "unprognostic (4.38e-2)" "unprognostic (3.14e-3)" "unprognostic (4.56e-3)" "unprognostic (1.82e-1)" "unprognostic (1.73e-3)" "unprognostic (1.98e-1)" "unprognostic (5.59e-2)" "unprognostic (4.55e-2)" "unprognostic (2.95e-1)" CNOT6 "CCR4, Ccr4a, KIAA1194" ENSG00000113300 "CCR4-NOT transcription complex subunit 6" Q9ULM6 5 180494379-180578358 "Enzymes, Predicted intracellular proteins" "RNA-mediated gene silencing, Transcription, Transcription regulation, Translation regulation" "Activator, Exonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044568 Approved Approved Cytosol NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 46 Cytosol "HPA044568: " "unprognostic (2.93e-2)" "unprognostic (7.37e-3)" "unprognostic (7.37e-3)" "unprognostic (9.83e-3)" "unprognostic (2.78e-2)" "unprognostic (9.07e-2)" "unprognostic (2.48e-1)" "unprognostic (6.87e-2)" "unprognostic (1.46e-1)" "potential prognostic unfavorable (1.55e-4)" "potential prognostic favorable (3.58e-7)" "unprognostic (1.00e-3)" "unprognostic (1.68e-1)" "potential prognostic unfavorable (8.36e-7)" "unprognostic (2.81e-2)" "unprognostic (1.56e-1)" "unprognostic (6.99e-2)" "unprognostic (2.27e-1)" "unprognostic (3.81e-1)" "unprognostic (4.40e-2)" "unprognostic (1.07e-2)" "unprognostic (2.28e-2)" "unprognostic (3.20e-2)" "unprognostic (1.90e-2)" "unprognostic (1.48e-3)" "unprognostic (2.94e-1)" "unprognostic (9.66e-2)" "unprognostic (2.41e-1)" "unprognostic (1.17e-1)" "unprognostic (4.10e-2)" "unprognostic (1.67e-1)" CNOT6L "Ccr4b, DKFZp434K098" ENSG00000138767 "CCR4-NOT transcription complex subunit 6 like" Q96LI5 4 77713387-77819615 "Enzymes, Predicted intracellular proteins" "mRNA processing, RNA-mediated gene silencing, Transcription, Transcription regulation, Translation regulation" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Innate lymphoid cells: 660.5;NK-cells: 1164.4;T-cells: 1249.6" "Cell type enhanced" "Detected in all" "leukocyte: 725.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042688 Uncertain Supported Cytosol NA NA "Cluster 32: Basophils - Transcription" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 16: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 9: T-cells - Adaptive immunity: Regulation" 68 Cytosol "HPA042688: " "unprognostic (6.68e-3)" "unprognostic (4.19e-1)" "unprognostic (4.73e-1)" "unprognostic (2.25e-1)" "potential prognostic favorable (8.61e-4)" "unprognostic (2.08e-2)" "unprognostic (1.23e-1)" "unprognostic (3.66e-1)" "unprognostic (1.65e-2)" "unprognostic (5.66e-2)" "validated prognostic favorable (3.21e-8)" "validated prognostic favorable (4.35e-6)" "unprognostic (5.11e-2)" "unprognostic (9.89e-2)" "unprognostic (6.19e-3)" "unprognostic (9.98e-2)" "unprognostic (4.35e-2)" "unprognostic (1.38e-1)" "unprognostic (1.19e-1)" "unprognostic (6.79e-2)" "unprognostic (1.72e-1)" "unprognostic (4.45e-1)" "unprognostic (4.97e-2)" "unprognostic (1.88e-1)" "unprognostic (2.16e-2)" "unprognostic (4.28e-2)" "unprognostic (7.88e-2)" "unprognostic (1.13e-1)" "unprognostic (1.05e-1)" "unprognostic (2.66e-2)" "unprognostic (2.80e-2)" CNOT7 CAF1 ENSG00000198791 "CCR4-NOT transcription complex subunit 7" Q9UIV1 8 17224966-17246878 "Enzymes, Predicted intracellular proteins" "RNA-mediated gene silencing, Transcription, Transcription regulation, Translation regulation" "Exonuclease, Hydrolase, Nuclease, Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069543 Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 80 "Nuclear bodies" Nucleoplasm "HPA069543: " "potential prognostic favorable (5.01e-5)" "unprognostic (8.73e-2)" "unprognostic (6.89e-2)" "unprognostic (6.04e-2)" "unprognostic (1.16e-3)" "unprognostic (7.14e-2)" "unprognostic (3.43e-1)" "unprognostic (1.77e-2)" "unprognostic (3.26e-2)" "unprognostic (2.22e-3)" "potential prognostic favorable (3.58e-8)" "unprognostic (3.45e-3)" "unprognostic (1.17e-1)" "potential prognostic unfavorable (1.85e-4)" "unprognostic (3.30e-2)" "unprognostic (9.88e-2)" "unprognostic (2.42e-1)" "unprognostic (2.28e-1)" "unprognostic (3.48e-2)" "unprognostic (1.33e-1)" "unprognostic (1.41e-2)" "unprognostic (9.55e-2)" "unprognostic (9.36e-2)" "unprognostic (1.03e-1)" "unprognostic (2.80e-2)" "unprognostic (6.38e-3)" "unprognostic (4.61e-2)" "unprognostic (1.35e-1)" "unprognostic (3.12e-1)" "unprognostic (1.23e-1)" "unprognostic (5.07e-2)" CNOT8 "CAF1, CALIF, hCAF1, POP2" ENSG00000155508 "CCR4-NOT transcription complex subunit 8" Q9UFF9 5 154857553-154876792 "Enzymes, Plasma proteins, Predicted intracellular proteins" "RNA-mediated gene silencing, Transcription, Transcription regulation, Translation regulation" "Exonuclease, Hydrolase, Nuclease, Repressor, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cell type enriched" "Detected in all" 4 "endothelial cell: 197.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051398 Approved NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 15: Bone marrow - Innate immune response" "Cluster 8: Immune cells - Immune response" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 104: Brain endothelial cells - Blood brain barrier" 44 "HPA051398: " "unprognostic (6.49e-3)" "unprognostic (2.77e-1)" "unprognostic (1.63e-2)" "unprognostic (1.38e-1)" "unprognostic (5.14e-1)" "unprognostic (2.49e-1)" "unprognostic (1.11e-1)" "unprognostic (1.02e-1)" "unprognostic (2.49e-1)" "potential prognostic unfavorable (3.72e-4)" "potential prognostic favorable (6.26e-6)" "unprognostic (4.24e-2)" "unprognostic (2.22e-1)" "unprognostic (5.81e-3)" "unprognostic (2.68e-2)" "unprognostic (3.29e-1)" "unprognostic (9.23e-3)" "unprognostic (2.49e-2)" "unprognostic (1.15e-1)" "unprognostic (1.32e-1)" "unprognostic (1.99e-2)" "unprognostic (1.41e-2)" "unprognostic (1.47e-2)" "unprognostic (2.22e-1)" "unprognostic (3.72e-2)" "unprognostic (3.62e-2)" "unprognostic (8.30e-2)" "unprognostic (4.24e-2)" "unprognostic (4.78e-1)" "unprognostic (5.10e-3)" "unprognostic (2.46e-1)" CNOT9 "CAF40, CT129, RCD1, RCD1+, RQCD1" ENSG00000144580 "CCR4-NOT transcription complex subunit 9" Q92600 2 218568580-218597080 "Predicted intracellular proteins" "RNA-mediated gene silencing, Transcription, Transcription regulation, Translation regulation" "Activator, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046622 Approved Approved "Cytoplasmic bodies" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 55: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 103: Non-specific - Basic cellular processes" 49 "Cytoplasmic bodies" "HPA046622: " "unprognostic (5.72e-3)" "unprognostic (9.19e-2)" "unprognostic (1.72e-1)" "unprognostic (3.71e-2)" "unprognostic (2.43e-1)" "unprognostic (7.70e-2)" "unprognostic (3.86e-2)" "unprognostic (2.27e-3)" "unprognostic (4.64e-2)" "unprognostic (8.91e-2)" "unprognostic (1.82e-1)" "unprognostic (3.24e-3)" "potential prognostic unfavorable (7.78e-7)" "unprognostic (2.24e-2)" "unprognostic (4.77e-3)" "unprognostic (1.49e-1)" "unprognostic (7.22e-2)" "unprognostic (1.30e-1)" "unprognostic (4.37e-2)" "unprognostic (8.22e-2)" "unprognostic (5.39e-2)" "unprognostic (6.85e-2)" "unprognostic (7.44e-2)" "unprognostic (9.09e-3)" "unprognostic (5.90e-3)" "unprognostic (4.28e-2)" "unprognostic (4.59e-2)" "unprognostic (4.08e-2)" "unprognostic (6.57e-2)" CNP ENSG00000173786 "2',3'-cyclic nucleotide 3' phosphodiesterase" P09543 17 41966763-41977740 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, RNA-binding" "Leukodystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 18 "brain: 1112.6" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 842.6" "Group enriched" "Detected in all" 8 "committed oligodendrocyte precursor: 508.1;oligodendrocyte: 962.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 149.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells" "Region enriched" "Detected in all" 4 "white matter: 1789.8" "Low region specificity" "Detected in all" "CAB002672, HPA023266, HPA023278, HPA023280, HPA023338" Enhanced Supported Approved "Plasma membrane" NA NA 38000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 80: Oligodendrocytes - Myelination" 13 "Plasma membrane" "CAB002672: , HPA023266: , HPA023278: , HPA023280: , HPA023338: " "unprognostic (4.08e-1)" "unprognostic (1.41e-1)" "unprognostic (1.87e-2)" "unprognostic (3.73e-1)" "unprognostic (1.90e-1)" "unprognostic (1.58e-2)" "unprognostic (1.56e-1)" "unprognostic (2.20e-1)" "unprognostic (1.13e-1)" "unprognostic (1.93e-2)" "unprognostic (1.44e-1)" "unprognostic (8.13e-2)" "unprognostic (3.78e-2)" "potential prognostic unfavorable (2.88e-4)" "unprognostic (2.49e-3)" "unprognostic (5.38e-3)" "unprognostic (1.44e-2)" "unprognostic (5.80e-2)" "unprognostic (1.28e-1)" "unprognostic (1.25e-1)" "unprognostic (3.14e-1)" "unprognostic (3.68e-2)" "unprognostic (9.54e-2)" "unprognostic (2.23e-1)" "unprognostic (1.24e-1)" "unprognostic (4.58e-2)" "unprognostic (1.77e-1)" "unprognostic (4.67e-2)" "unprognostic (8.67e-2)" "unprognostic (1.02e-1)" "unprognostic (2.65e-2)" CNPPD1 "C2orf24, CGI-57" ENSG00000115649 "Cyclin Pas1/PHO80 domain containing 1" Q9BV87 2 219171897-219178106 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 206.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049303 Uncertain NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 2 "HPA049303: " "unprognostic (9.48e-3)" "unprognostic (8.58e-2)" "unprognostic (7.50e-2)" "unprognostic (3.17e-1)" "unprognostic (1.57e-2)" "unprognostic (4.01e-1)" "unprognostic (1.57e-1)" "unprognostic (2.65e-3)" "unprognostic (1.19e-1)" "validated prognostic favorable (1.37e-8)" "validated prognostic favorable (7.06e-6)" "potential prognostic favorable (1.24e-6)" "potential prognostic unfavorable (6.13e-4)" "unprognostic (1.62e-3)" "unprognostic (1.84e-2)" "unprognostic (2.16e-1)" "unprognostic (9.75e-2)" "unprognostic (3.57e-2)" "unprognostic (2.54e-3)" "unprognostic (3.04e-2)" "unprognostic (5.68e-2)" "unprognostic (2.68e-2)" "unprognostic (1.15e-1)" "unprognostic (3.27e-2)" "unprognostic (8.96e-2)" "unprognostic (3.61e-3)" "unprognostic (1.77e-2)" "unprognostic (1.28e-1)" "unprognostic (1.54e-1)" "unprognostic (7.69e-2)" CNPY1 ENSG00000146910 "Canopy FGF signaling regulator 1" Q3B7I2 7 155474206-155555450 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 11 "brain: 8.5;pancreas: 2.2" "Cell type enhanced" "Detected in single" "Podocytes: 1.3" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 12 "Glioblastoma Multiforme (TCGA): 7.3" "Group enriched" "Detected in many" 5 "cerebellum: 26.3;midbrain: 8.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 3.4" HPA047400 Uncertain NA NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 70: DU4475 - Unknown function" "Cluster 105: Non-specific - Mixed function" "HPA047400: " "unprognostic (2.03e-3)" "unprognostic (1.36e-2)" "unprognostic (1.60e-1)" CNPY2 "HP10390, TMEM4, ZSIG9" ENSG00000257727 "Canopy FGF signaling regulator 2" Q9Y2B0 12 56309842-56316119 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 199.2;Epididymal principal cells: 194.0;Extravillous trophoblasts: 501.5;Migrating cytotrophoblasts: 213.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038465, HPA038466" Supported Supported Cytosol "Intracellular and membrane" "No annotated function" NA NA 410000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 70: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 9 Cytosol "HPA038465: , HPA038466: " "unprognostic (3.01e-1)" "unprognostic (4.08e-3)" "unprognostic (1.22e-1)" "unprognostic (1.54e-2)" "unprognostic (1.11e-1)" "unprognostic (6.97e-2)" "unprognostic (4.48e-2)" "potential prognostic favorable (6.03e-4)" "unprognostic (1.40e-2)" "unprognostic (9.66e-2)" "unprognostic (7.09e-3)" "unprognostic (1.06e-1)" "unprognostic (4.31e-2)" "validated prognostic unfavorable (4.32e-5)" "validated prognostic unfavorable (9.25e-7)" "unprognostic (8.40e-3)" "unprognostic (6.46e-2)" "unprognostic (2.81e-2)" "unprognostic (5.06e-2)" "unprognostic (1.68e-1)" "unprognostic (2.10e-1)" "unprognostic (5.56e-2)" "unprognostic (7.15e-2)" "unprognostic (1.24e-2)" "unprognostic (4.24e-3)" "unprognostic (1.05e-1)" "unprognostic (6.70e-2)" "unprognostic (5.30e-2)" "unprognostic (1.83e-1)" "unprognostic (2.69e-1)" "unprognostic (1.58e-2)" CNPY3 "CAG4A, TNRC5" ENSG00000137161 "Canopy FGF signaling regulator 3" Q9BT09 6 42929480-42939294 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Immunity, Innate immunity" Chaperone "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 253.1;Hofbauer cells: 344.4;Kupffer cells: 182.4;monocytes: 199.6;Neutrophils: 215.2;pDCs: 281.6" "Group enriched" "Detected in all" 4 "central nervous system macrophage: 129.5;leukocyte: 49.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016560 Uncertain Approved "Endoplasmic reticulum,Plasma membrane" "Intracellular and membrane" Immunity NA NA 15000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 35: RS4;11 - Unknown function" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 38 "Endoplasmic reticulum, Plasma membrane" "HPA016560: " "unprognostic (5.27e-2)" "unprognostic (1.38e-1)" "unprognostic (1.13e-2)" "unprognostic (3.90e-2)" "unprognostic (1.05e-1)" "unprognostic (1.82e-1)" "unprognostic (1.51e-2)" "unprognostic (1.21e-1)" "unprognostic (7.26e-2)" "unprognostic (1.04e-1)" "potential prognostic unfavorable (3.29e-4)" "unprognostic (4.44e-2)" "unprognostic (3.28e-1)" "unprognostic (2.42e-2)" "unprognostic (1.34e-2)" "unprognostic (9.05e-2)" "unprognostic (2.90e-2)" "unprognostic (2.01e-1)" "unprognostic (9.24e-2)" "unprognostic (7.81e-2)" "unprognostic (1.38e-2)" "unprognostic (2.09e-2)" "unprognostic (2.15e-1)" "unprognostic (3.32e-2)" "unprognostic (3.91e-1)" "unprognostic (1.91e-1)" "unprognostic (1.66e-2)" "unprognostic (2.09e-1)" "unprognostic (1.40e-1)" "unprognostic (3.51e-2)" "unprognostic (1.49e-2)" CNPY4 "MGC40499, PRAT4B" ENSG00000166997 "Canopy FGF signaling regulator 4" Q8N129 7 100119634-100125508 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 46.2;Decidual stromal cells: 56.9;Hepatic stellate cells: 51.6;Leydig cells: 27.9;Peritubular myoid cells: 29.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Kidney - Fibroblasts, Prostate - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014166, HPA025240" Uncertain Approved Vesicles "Intracellular and membrane" "No annotated function" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 75: Ovary - Mixed function" "Cluster 25: Non-specific - Transcription" "Cluster 39: Non-specific - Transcription" "Cluster 108: Fibroblasts - ECM organization" 2 Vesicles "HPA014166: , HPA025240: " "unprognostic (9.32e-2)" "unprognostic (4.31e-1)" "unprognostic (1.50e-1)" "unprognostic (3.04e-1)" "unprognostic (2.62e-2)" "unprognostic (3.72e-2)" "unprognostic (4.42e-3)" "unprognostic (9.32e-3)" "unprognostic (2.12e-1)" "unprognostic (4.57e-3)" "unprognostic (5.60e-3)" "unprognostic (9.78e-2)" "unprognostic (4.31e-3)" "potential prognostic unfavorable (4.43e-4)" "unprognostic (7.74e-3)" "unprognostic (2.94e-1)" "unprognostic (1.21e-1)" "unprognostic (1.55e-1)" "unprognostic (7.90e-2)" "unprognostic (2.49e-1)" "unprognostic (2.02e-2)" "unprognostic (5.47e-3)" "unprognostic (1.11e-1)" "unprognostic (7.78e-2)" "unprognostic (1.37e-3)" "unprognostic (1.26e-1)" "unprognostic (1.54e-1)" "unprognostic (3.29e-2)" "unprognostic (1.96e-1)" "unprognostic (2.40e-2)" "unprognostic (1.14e-1)" CNR1 "CANN6, CB-R, CB1, CB1A, CB1K5, CNR" ENSG00000118432 "Cannabinoid receptor 1" P21554 6 88139864-88166347 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets, Neurodegeneration, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 18.3;brain: 18.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 41.3;Brain excitatory neurons: 73.2;Brain inhibitory neurons: 246.3;Corticotrophs: 73.8;Gonadotrophs: 40.4;Other brain neurons: 62.4;Pericytes: 138.8;Somatotrophs: 128.9;Thyrotrophs: 57.4" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 394.9;CGE interneuron: 892.7" "Cancer enriched" "Detected in many" 9 "Glioblastoma Multiforme (TCGA): 26.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Brain cancer: 9.9;lymphoma: 15.1;thyroid cancer: 4.0" "Kidney - Macrophages, Pituitary gland - Corticotropes, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042256, HPA069945" Enhanced Supported Supported "Plasma membrane,Actin filaments" NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 110: Mural cells - ECM organization" 3 "Plasma membrane" "Actin filaments" "HPA042256: , HPA069945: " "unprognostic (8.60e-2)" "unprognostic (1.58e-1)" "unprognostic (1.22e-1)" "unprognostic (3.74e-1)" "unprognostic (1.77e-1)" "unprognostic (2.45e-1)" "unprognostic (3.48e-2)" "unprognostic (1.33e-1)" "unprognostic (1.07e-2)" "unprognostic (9.39e-2)" "unprognostic (1.04e-1)" "unprognostic (1.12e-2)" "unprognostic (1.70e-1)" "unprognostic (9.62e-2)" "unprognostic (1.06e-1)" "unprognostic (2.89e-1)" "unprognostic (4.13e-3)" "unprognostic (3.13e-3)" CNR2 CB2 ENSG00000188822 "Cannabinoid receptor 2" P34972 1 23870515-23913362 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 3.1;lymphoid tissue: 8.4" "Group enriched" "Detected in some" 5 "B-cells: 160.7;Thymocytes: 93.2" "Cell type enriched" "Detected in some" 8 "leukocyte: 8.8" "Cancer enriched" "Detected in single" 5 "Testicular Germ Cell Tumor (TCGA): 4.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "basophil: 49.2;eosinophil: 35.1;memory B-cell: 29.6;naive B-cell: 27.9;NK-cell: 19.4" "Group enriched" "Detected in many" 9 "B-cells: 29.6;granulocytes: 49.2;NK-cells: 19.4" "Group enriched" "Detected in some" 14 "Leukemia: 3.1;lymphoma: 6.3" "Lung - B-cells (Lung), Spleen - B-cells (Spleen)" "Not detected" "Not detected" "Not detected" "Not detected" CAB009719 Uncertain NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 24 "CAB009719: " "potential prognostic favorable (1.39e-4)" "unprognostic (1.33e-1)" "unprognostic (1.35e-2)" "unprognostic (5.54e-3)" "unprognostic (2.37e-1)" CNRIP1 "C2orf32, CRIP1, CRIP1a, CRIP1b, DKFZP566K1924" ENSG00000119865 "Cannabinoid receptor interacting protein 1" Q96F85 2 68284171-68320051 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 75.2" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 76.8;Erythrocyte progenitors: 89.6;Hofbauer cells: 121.4;Kupffer cells: 77.9;Mast cells: 131.9;Megakaryocyte-Erythroid progenitors: 191.3;Oocytes: 409.9;Smooth muscle cells: 75.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 30.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 109 "basophil: 12.3" "Lineage enriched" "Detected in single" 109 "granulocytes: 12.3" "Cancer enhanced" "Detected in many" "Neuroblastoma: 51.2" "Liver - Vascular endothelial cells, Lung - Fibroblasts_1, Minor Salivary Gland - Endothelial cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035337 Approved Cytosol NA NA 43000 "Cluster 46: Basophils - Proteolysis" "Cluster 65: Brain - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 41: Oocytes - Oogenesis" 5 Cytosol "HPA035337: " "unprognostic (3.07e-1)" "unprognostic (2.37e-1)" "unprognostic (2.25e-1)" "unprognostic (9.89e-3)" "unprognostic (5.10e-2)" "unprognostic (9.17e-2)" "unprognostic (7.96e-2)" "unprognostic (4.28e-3)" "unprognostic (8.01e-2)" "unprognostic (9.28e-2)" "unprognostic (1.49e-3)" "unprognostic (1.25e-3)" "unprognostic (1.03e-2)" "unprognostic (2.60e-1)" "unprognostic (7.54e-2)" "unprognostic (1.54e-2)" "unprognostic (1.07e-1)" "unprognostic (8.57e-3)" "unprognostic (2.91e-1)" "unprognostic (1.37e-2)" "unprognostic (5.01e-2)" "unprognostic (1.09e-2)" "unprognostic (1.43e-1)" "unprognostic (8.48e-2)" "unprognostic (1.09e-1)" "unprognostic (6.62e-2)" "unprognostic (2.25e-1)" "unprognostic (1.03e-2)" "unprognostic (1.63e-2)" "unprognostic (1.11e-2)" "unprognostic (2.27e-2)" CNST "C1orf71, FLJ32001, PPP1R64" ENSG00000162852 "Consortin, connexin sorting protein" Q6PJW8 1 246566444-246668595 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 419.1;Hematopoietic stem cells: 359.1;Platelets: 1230.7;Thymic myoid cells: 365.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007225, HPA007226" Approved Supported Vesicles NA NA 130000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 51: Secretory epithelial cells - Mixed function" 6 Vesicles "HPA007225: , HPA007226: " "unprognostic (3.29e-3)" "unprognostic (4.63e-3)" "unprognostic (3.61e-1)" "unprognostic (5.64e-2)" "unprognostic (1.14e-1)" "unprognostic (1.09e-2)" "unprognostic (1.93e-1)" "potential prognostic favorable (5.72e-4)" "unprognostic (5.61e-2)" "unprognostic (4.46e-2)" "validated prognostic favorable (4.21e-7)" "validated prognostic favorable (3.86e-4)" "unprognostic (1.05e-2)" "unprognostic (8.73e-2)" "unprognostic (1.54e-1)" "unprognostic (6.85e-2)" "unprognostic (2.45e-2)" "unprognostic (1.26e-1)" "unprognostic (8.00e-2)" "unprognostic (4.05e-1)" "unprognostic (1.82e-2)" "unprognostic (6.66e-2)" "unprognostic (3.60e-2)" "unprognostic (1.24e-1)" "unprognostic (2.04e-1)" "unprognostic (5.34e-2)" "unprognostic (1.90e-1)" "unprognostic (8.24e-2)" "unprognostic (2.35e-1)" "unprognostic (8.39e-3)" "unprognostic (1.04e-1)" CNTD1 "CNTD, FLJ40137" ENSG00000176563 "Cyclin N-terminal domain containing 1" Q8N815 17 42798800-42811587 "Predicted intracellular proteins, Predicted membrane proteins" Meiosis "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 12 "testis: 39.5" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 159.6;Early spermatids: 61.3;Gastric chief cells: 55.7;Late primary spermatocytes: 181.0;Late spermatids: 174.3;Mucous neck cells: 54.7;Parietal cells: 111.4;Respiratory ciliated cells: 50.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA072363 Approved Nucleoplasm,Vesicles NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 70: DU4475 - Unknown function" "Cluster 3: Early primary spermatocytes - Early meiosis" Nucleoplasm Vesicles "HPA072363: " "unprognostic (9.90e-2)" "unprognostic (6.62e-3)" "unprognostic (7.32e-3)" "unprognostic (1.52e-1)" "unprognostic (1.38e-2)" "unprognostic (2.19e-2)" "unprognostic (1.89e-3)" "unprognostic (2.41e-1)" "unprognostic (2.12e-1)" "unprognostic (4.22e-3)" CNTF HCNTF ENSG00000242689 "Ciliary neurotrophic factor" P26441 11 58622665-58625733 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.5;brain: 11.6" "Cell type enhanced" "Detected in some" "Melanocytes: 2.0;Schwann cells: 1.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019654 Approved Approved Vesicles NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 69: Skin cancer - ECM organization" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 16 Vesicles "HPA019654: " "unprognostic (4.92e-3)" "unprognostic (1.21e-1)" "unprognostic (2.95e-2)" "potential prognostic favorable (1.30e-5)" "unprognostic (3.75e-2)" "unprognostic (1.09e-1)" CNTFR ENSG00000122756 "Ciliary neurotrophic factor receptor" P26992 9 34551432-34590140 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 106.8;skeletal muscle: 120.6" "Cell type enhanced" "Detected in many" "Adipocytes: 59.8;Adrenal medulla cells: 53.2;Astrocytes: 76.2;Bergmann glia: 80.2;Breast lactating cells: 150.2;Early spermatids: 33.3;Epididymal basal cells: 30.0;Fibroblasts: 34.4;Hepatic stellate cells: 38.7;Müller glia: 83.4;Myonuclei: 46.2;Schwann cells: 31.3" "Cell type enhanced" "Detected in many" "astrocyte: 80.2;Bergmann glia: 81.1" "Group enriched" "Detected in many" 4 "Glioblastoma Multiforme (TCGA): 42.2;Ovary Serous Cystadenocarcinoma (TCGA): 11.3;Testicular Germ Cell Tumor (TCGA): 13.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 12 "Neuroblastoma: 93.7" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Lung - Fibroblasts_2, Minor Salivary Gland - Adipocytes (Minor salivary gland), Pancreas - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025310 Approved NA NA 11000000 "Cluster 25: Non-specific - Basic cellular processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 108: Fibroblasts - ECM organization" 5 "CAB025310: " "unprognostic (2.63e-1)" "unprognostic (2.06e-1)" "unprognostic (3.14e-1)" "unprognostic (6.32e-2)" "unprognostic (3.15e-2)" "unprognostic (2.81e-1)" "unprognostic (8.06e-2)" "potential prognostic favorable (6.55e-4)" "unprognostic (2.98e-2)" "unprognostic (1.08e-1)" "unprognostic (1.90e-1)" "unprognostic (5.43e-2)" "unprognostic (1.66e-1)" "unprognostic (4.07e-2)" "unprognostic (4.37e-2)" "unprognostic (1.56e-2)" "unprognostic (6.70e-3)" "unprognostic (5.75e-2)" "unprognostic (1.75e-1)" "unprognostic (7.25e-2)" "unprognostic (4.67e-3)" "unprognostic (3.31e-2)" "unprognostic (3.45e-2)" "unprognostic (3.48e-1)" CNTLN "bA340N12.1, C9orf101, C9orf39, FLJ20276" ENSG00000044459 Centlein Q9NXG0 9 17134982-17503923 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibro-adipogenic progenitors: 243.3;Kupffer cells: 234.7;Lactotrophs: 247.0;Neutrophil progenitors: 240.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 3.9" "Lineage enriched" "Detected in single" 5 "monocytes: 3.9" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Spleen - Endothelial cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007201, HPA036728, HPA036729" Uncertain Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 75: Ovary - Mixed function" "Cluster 25: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Transcription" 4 Centrosome "Nucleoplasm, Cytosol" "HPA007201: , HPA036728: , HPA036729: " "unprognostic (5.29e-2)" "unprognostic (2.13e-2)" "unprognostic (2.50e-1)" "unprognostic (1.40e-2)" "unprognostic (2.98e-1)" "unprognostic (9.79e-3)" "unprognostic (3.25e-1)" "unprognostic (1.23e-1)" "unprognostic (1.12e-1)" "unprognostic (9.80e-2)" "unprognostic (2.24e-3)" "unprognostic (1.53e-2)" "unprognostic (7.11e-2)" "unprognostic (4.14e-2)" "unprognostic (2.22e-2)" "unprognostic (4.78e-2)" "unprognostic (7.82e-2)" "unprognostic (1.17e-2)" "unprognostic (1.14e-1)" "unprognostic (4.94e-2)" "unprognostic (1.53e-2)" "unprognostic (2.37e-1)" "potential prognostic unfavorable (3.75e-4)" "unprognostic (1.86e-1)" "unprognostic (3.81e-1)" "unprognostic (4.38e-2)" "unprognostic (1.59e-2)" "unprognostic (6.64e-2)" "unprognostic (4.55e-2)" "unprognostic (6.72e-2)" "unprognostic (1.65e-1)" CNTN1 "F3, GP135" ENSG00000018236 "Contactin 1" Q12860 12 40692439-41072415 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Notch signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 120.8" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 797.8;Astrocytes: 1182.0;Bergmann glia: 514.8;Brain excitatory neurons: 1217.3;Brain inhibitory neurons: 758.3;Cone photoreceptor cells: 579.6;Corticotrophs: 588.3;Gonadotrophs: 430.5;Lactotrophs: 813.1;Oligodendrocyte progenitor cells: 1513.5;Other brain neurons: 734.3;Retinal amacrine cells: 448.9;Retinal bipolar cells: 454.4;Retinal ganglion cells: 548.5;Thyrotrophs: 665.9" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 43.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.5" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in many" 6 "Gallbladder cancer: 245.7" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Minor Salivary Gland - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025200, HPA070467" Enhanced Approved "Intracellular and membrane" "Cell adhesion" NA NA 130000000 "Cluster 22: Eosinophils - Transcription" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 14: Neurons - Synaptic function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 6 "CAB025200: , HPA070467: " "unprognostic (1.51e-1)" "unprognostic (1.76e-1)" "unprognostic (1.04e-1)" "unprognostic (1.52e-2)" "unprognostic (3.12e-1)" "unprognostic (2.67e-1)" "unprognostic (1.45e-3)" "unprognostic (2.96e-1)" "unprognostic (5.94e-2)" "unprognostic (3.69e-2)" "unprognostic (4.47e-2)" "unprognostic (4.73e-2)" "unprognostic (2.55e-1)" "unprognostic (4.62e-2)" "unprognostic (1.41e-3)" "unprognostic (1.10e-2)" "unprognostic (1.71e-2)" "unprognostic (1.92e-1)" "unprognostic (1.86e-1)" "unprognostic (1.14e-1)" "unprognostic (3.48e-3)" "unprognostic (1.36e-1)" "unprognostic (2.99e-2)" CNTN2 "AXT, TAG-1, TAX, TAX1" ENSG00000184144 "Contactin 2" Q02246 1 205042937-205078289 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Cell adhesion" Epilepsy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "brain: 157.3" "Cell type enriched" "Detected in some" 7 "Oligodendrocytes: 426.7" "Group enriched" "Detected in all" 5 "committed oligodendrocyte precursor: 218.1;oligodendrocyte: 537.4" "Cancer enriched" "Detected in some" 9 "Glioblastoma Multiforme (TCGA): 12.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Neuroblastoma: 5.8" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal medulla cells, Pituitary gland - Thyrotropes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001397, HPA012497" Approved "Secreted in brain" "Cell adhesion" NA NA 71000 "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 80: Oligodendrocytes - Myelination" 6 "HPA001397: , HPA012497: " "unprognostic (1.53e-2)" "unprognostic (3.92e-2)" "unprognostic (7.23e-2)" "unprognostic (7.60e-2)" CNTN3 "BIG-1, PANG" ENSG00000113805 "Contactin 3" Q9P232 3 74262568-74614659 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 393.6;Corticotrophs: 325.6;Ependymal cells: 481.6;Gonadotrophs: 317.9;Oligodendrocyte progenitor cells: 256.7;Pituitary stem cells: 891.8;Prostatic glandular cells: 243.3;Retinal amacrine cells: 254.8;Retinal horizontal cells: 246.4;Retinal pigment epithelial cells: 549.9;Thymic myoid cells: 257.0;Thyrotrophs: 258.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 5.8" "Region enriched" "Detected in all" 28 "cerebral cortex: 1682.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal medulla cells, Lung - Respiratory ciliated cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003341 Approved "Intracellular and membrane" "Cell adhesion" NA NA 23000000 "Cluster 73: Brain - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" "HPA003341: " "unprognostic (1.12e-1)" "unprognostic (3.65e-2)" "unprognostic (1.61e-1)" "unprognostic (4.63e-2)" "potential prognostic favorable (1.95e-6)" "unprognostic (5.15e-3)" "unprognostic (5.61e-2)" "unprognostic (5.49e-2)" "unprognostic (3.51e-1)" "unprognostic (2.66e-2)" "unprognostic (9.61e-2)" "unprognostic (1.03e-1)" "unprognostic (2.78e-1)" "unprognostic (2.19e-1)" "unprognostic (2.21e-1)" "unprognostic (4.22e-1)" CNTN4 BIG-2 ENSG00000144619 "Contactin 4" Q8IWV2 3 2098813-3057959 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 21.2" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 779.0;Brain inhibitory neurons: 845.6;Lactotrophs: 1420.6;Medullary thymic epithelial cells: 1024.9;Pituicytes/FSCs: 1263.3;Pituitary stem cells: 2322.6;Podocytes: 677.0;Retinal amacrine cells: 757.9;Retinal bipolar cells: 1297.8;Retinal horizontal cells: 2341.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 5.2;Rhabdoid: 5.2" "Adipose subcutaneous - Smooth muscle cells, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skin - Outer root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" "Cell adhesion" NA NA 23000000 "Cluster 42: Retina - Visual perception" "Cluster 38: Sub-cortical - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 109: Neurons - Neuronal signaling" "unprognostic (3.23e-1)" "unprognostic (2.05e-1)" "unprognostic (3.75e-2)" "unprognostic (3.29e-1)" "unprognostic (1.82e-1)" "potential prognostic favorable (1.38e-4)" "unprognostic (1.28e-3)" "unprognostic (8.67e-2)" "unprognostic (3.00e-2)" "unprognostic (7.84e-2)" "unprognostic (1.33e-1)" "unprognostic (1.18e-2)" "unprognostic (3.95e-1)" "unprognostic (6.47e-3)" "unprognostic (1.88e-1)" "unprognostic (1.34e-1)" "unprognostic (2.09e-2)" "unprognostic (2.33e-2)" "unprognostic (1.87e-2)" "unprognostic (3.64e-2)" "unprognostic (6.46e-2)" CNTN5 "hNB-2, NB-2" ENSG00000149972 "Contactin 5" O94779 11 99020949-100358885 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.9;placenta: 2.4;salivary gland: 1.9;thyroid gland: 1.8" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 1090.7;Brain inhibitory neurons: 1173.1;Corticotrophs: 1464.5;Lactotrophs: 1223.4;Oligodendrocyte progenitor cells: 367.1;Other brain neurons: 469.1;Retinal amacrine cells: 468.9;Salivary acinar cells: 1140.7;Salivary myoepithelial cells: 361.5" "Cell type enhanced" "Detected in all" "miscellaneous: 5880.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Myeloma: 1.5" "Colon - Colon enteroendocrine cells, Lung - Respiratory ciliated cells, Pancreas - Beta cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039492, HPA041223" Approved "Intracellular and membrane" "Cell adhesion" NA NA 610000 "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 109: Neurons - Neuronal signaling" "HPA039492: , HPA041223: " "unprognostic (2.69e-1)" "unprognostic (2.00e-1)" CNTN6 NB-3 ENSG00000134115 "Contactin 6" Q9UQ52 3 1092658-1404217 "Predicted membrane proteins" "Cell adhesion, Notch signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 3.2;brain: 8.8;thyroid gland: 9.0" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 444.8;Alveolar cells type 1: 224.0;Brain excitatory neurons: 185.8;Brain inhibitory neurons: 73.4;Oligodendrocyte progenitor cells: 80.2;Oocytes: 69.1;Other brain neurons: 72.3;Pituicytes/FSCs: 144.9;Retinal amacrine cells: 67.6;Transitional alveolar cells: 79.8" "Cell type enhanced" "Detected in all" "upper rhombic lip: 532.0" "Group enriched" "Detected in some" 15 "Kidney Renal Papillary Cell Carcinoma (TCGA): 11.5;Thyroid Carcinoma (TCGA): 5.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "testis cancer: 1.5;thyroid cancer: 1.9" "Lung - Alveolar cells type 1, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA016645 Uncertain NA NA 1300000 "Cluster 27: Cerebellum - Synaptic function" "Cluster 35: Non-specific - DNA binding" "Cluster 55: Lymphoma - Immune response" "Cluster 2: Cerebellar granular cells - Neuronal signaling" "HPA016645: " "unprognostic (1.42e-2)" "potential prognostic favorable (3.74e-4)" "unprognostic (3.62e-2)" "unprognostic (6.87e-2)" CNTNAP1 "Caspr, CNTNAP, NRXN4, p190" ENSG00000108797 "Contactin associated protein 1" P78357 17 42682531-42699993 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion" "Disease variant, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 72.7" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 48.7;Brain inhibitory neurons: 39.4;Endometrial stromal cells: 24.7;Other brain neurons: 41.0;Retinal amacrine cells: 26.9;Retinal bipolar cells: 49.6;Retinal ganglion cells: 65.7;Smooth muscle cells: 22.5" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 20.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011772 Approved Approved Nucleoplasm NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 24 Nucleoplasm "HPA011772: " "unprognostic (1.84e-2)" "unprognostic (1.95e-1)" "unprognostic (2.83e-1)" "unprognostic (3.49e-2)" "unprognostic (4.24e-2)" "unprognostic (7.91e-2)" "unprognostic (3.06e-2)" "unprognostic (1.98e-1)" "unprognostic (1.69e-1)" "potential prognostic unfavorable (3.35e-6)" "unprognostic (7.36e-2)" "unprognostic (1.13e-2)" "unprognostic (4.30e-3)" "unprognostic (5.16e-3)" "unprognostic (8.09e-2)" "unprognostic (4.81e-2)" "unprognostic (9.28e-2)" "unprognostic (1.09e-1)" "unprognostic (2.99e-2)" "unprognostic (1.49e-1)" "unprognostic (4.45e-2)" "unprognostic (7.49e-2)" "unprognostic (3.33e-1)" "unprognostic (8.98e-2)" "unprognostic (5.91e-2)" "unprognostic (1.24e-1)" "unprognostic (5.93e-3)" "unprognostic (2.35e-2)" "unprognostic (8.13e-2)" "unprognostic (3.66e-1)" CNTNAP2 "Caspr2, KIAA0868, NRXN4" ENSG00000174469 "Contactin associated protein 2" Q9UHC6 7 146116002-148420998 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Autism, Autism spectrum disorder, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 34.8;retina: 13.4" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 3026.9;Brain inhibitory neurons: 4144.2;Gonadotrophs: 1002.5;Oligodendrocyte progenitor cells: 779.0;Oligodendrocytes: 1222.4;Other brain neurons: 2546.3;Prostatic glandular cells: 1369.2;Retinal amacrine cells: 1233.4;Retinal bipolar cells: 872.7;Retinal ganglion cells: 1324.9;Thyrotrophs: 785.9" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 8.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 2.5" "Lineage enriched" "Detected in single" 25 "B-cells: 2.5" "Cancer enhanced" "Detected in many" "Neuroblastoma: 5.8" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002739 Enhanced NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 109: Neurons - Neuronal signaling" 8 "HPA002739: " "unprognostic (5.40e-2)" "unprognostic (2.02e-2)" "unprognostic (7.70e-2)" "unprognostic (1.74e-1)" "potential prognostic favorable (1.06e-5)" "unprognostic (1.24e-1)" "unprognostic (5.69e-2)" "unprognostic (1.73e-1)" "unprognostic (1.64e-1)" "unprognostic (2.54e-1)" "unprognostic (1.92e-1)" "unprognostic (1.94e-3)" "unprognostic (1.05e-1)" "unprognostic (3.49e-1)" "unprognostic (2.25e-1)" "unprognostic (2.16e-2)" "unprognostic (4.08e-1)" CNTNAP3 "CASPR3, CNTNAP3A, FLJ14195, KIAA1714" ENSG00000106714 "Contactin associated protein family member 3" Q9BZ76 9 39064710-39288315 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Neutrophils: 816.1" "Cell type enhanced" "Detected in many" "MGE interneuron: 128.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 18 "neutrophil: 7.4" "Lineage enriched" "Detected in single" 75 "granulocytes: 7.4" "Low cancer specificity" "Detected in many" HPA047731 Uncertain "Intracellular and membrane" "Cell adhesion" NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 2: Non-specific - Mixed function" "Cluster 33: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 29: Neutrophils - Innate immune cellular maintenance" "HPA047731: " "potential prognostic unfavorable (3.72e-4)" "unprognostic (3.72e-1)" "unprognostic (8.61e-3)" "unprognostic (1.81e-1)" "unprognostic (1.03e-1)" "unprognostic (7.36e-3)" "unprognostic (1.80e-1)" "unprognostic (2.79e-1)" "unprognostic (2.69e-1)" "unprognostic (3.55e-2)" "unprognostic (1.08e-1)" "unprognostic (1.39e-2)" "unprognostic (2.35e-1)" "unprognostic (8.46e-2)" CNTNAP3B ENSG00000154529 "Contactin associated protein family member 3B" Q96NU0 9 41890314-42129510 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 84.5;Bergmann glia: 260.8;Brain inhibitory neurons: 80.5;Choroid plexus epithelial cells: 84.5;Ependymal cells: 97.3;Lymphatic endothelial cells: 162.7;Proximal tubule cells: 448.3;Renal collecting duct principal cells: 86.1;Vascular endothelial cells: 116.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "neutrophil: 3.5" "Lineage enriched" "Detected in single" 35 "granulocytes: 3.5" "Low cancer specificity" "Detected in many" HPA047731 Uncertain NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 33: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" "HPA047731: " "potential prognostic unfavorable (6.93e-4)" "unprognostic (2.52e-2)" "unprognostic (1.07e-3)" "unprognostic (8.77e-2)" "unprognostic (6.67e-2)" "unprognostic (2.21e-2)" "unprognostic (2.44e-2)" "unprognostic (6.73e-2)" "unprognostic (1.80e-2)" "unprognostic (1.36e-1)" "unprognostic (1.31e-2)" "unprognostic (5.98e-3)" "unprognostic (2.19e-1)" "unprognostic (3.36e-2)" "unprognostic (1.82e-2)" "unprognostic (3.88e-2)" "unprognostic (2.01e-2)" "unprognostic (1.98e-1)" "unprognostic (4.97e-2)" "unprognostic (1.32e-1)" "unprognostic (4.48e-3)" "unprognostic (8.28e-2)" "unprognostic (4.20e-2)" CNTNAP3C ENSG00000283378 "Contactin associated protein family member 3C" 9 61330717-61453030 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 8 "bone marrow: 10.5" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 27.1;Epicardial cells: 11.4;Neutrophil progenitors: 46.1;Neutrophils: 143.2;Undifferentiated spermatogonia: 10.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 12 "neutrophil: 31.0" "Lineage enriched" "Detected in single" 184 "granulocytes: 31.0" "Low cancer specificity" "Detected in many" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 33: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 29: Neutrophils - Innate immune cellular maintenance" "unprognostic (6.96e-3)" "unprognostic (3.10e-2)" "unprognostic (4.91e-1)" CNTNAP4 "CASPR4, KIAA1763" ENSG00000152910 "Contactin associated protein family member 4" Q9C0A0 16 76277278-76560757 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "brain: 94.7" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 2.2;Early spermatids: 8.4;Late primary spermatocytes: 3.5;Late spermatids: 2.7;Loop of henle epithelial cells: 1.6;Oligodendrocytes: 1.1;Papillary tip epithelial cells: 1.6;Podocytes: 1.0;Proximal tubule cells: 1.3;Renal collecting duct intercalated cells: 1.3;Renal collecting duct principal cells: 1.9;Renal connecting tubule cells: 1.8" "Cell type enhanced" "Detected in some" "CGE interneuron: 1.0;oligodendrocyte: 1.6" "Cancer enriched" "Detected in single" 8 "Glioblastoma Multiforme (TCGA): 2.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 2.6;Neuroblastoma: 2.5;Rhabdoid: 2.7" "Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Pituitary gland - Thyrotropes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031859 Enhanced NA NA 7600000 "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 5: Rhabdoid - Unknown function" "Cluster 105: Non-specific - Mixed function" "HPA031859: " "unprognostic (4.16e-2)" "unprognostic (2.16e-2)" "unprognostic (3.37e-2)" CNTNAP5 "caspr5, FLJ31966" ENSG00000155052 "Contactin associated protein family member 5" Q8WYK1 2 124025287-124921219 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 4.7;retina: 2.7" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 425.5;Brain excitatory neurons: 683.3;Brain inhibitory neurons: 892.1;Epididymal clear cells: 694.0;Oligodendrocyte progenitor cells: 1167.7;Other brain neurons: 470.0;Renal collecting duct intercalated cells: 294.9;Retinal amacrine cells: 236.2;Retinal bipolar cells: 670.0;Retinal ganglion cells: 757.1" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in single" 9 "Kidney Chromophobe (TCGA): 6.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Neuroblastoma: 1.5" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Kidney - Intercalated cells, Pancreas - Alpha cells, Pituitary gland - Undifferentiated cells (Pituitary gland)" "Low region specificity" "Detected in all" "HPA069095, HPA069356" Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 1: Neuronal - Visual perception" "Cluster 109: Neurons - Neuronal signaling" "Nucleoli fibrillar center" "Nucleoplasm, Vesicles" "HPA069095: , HPA069356: " "unprognostic (5.13e-3)" "unprognostic (1.59e-3)" "unprognostic (1.14e-3)" CNTRL "CEP1, CEP110" ENSG00000119397 Centriolin Q7Z7A1 9 121074660-121177729 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 20.3;testis: 28.4" "Cell type enhanced" "Detected in all" "Early primary spermatocytes: 406.1;Ependymal cells: 253.1;Fallopian tube ciliated cells: 257.8;Late primary spermatocytes: 401.9;Monocyte progenitors: 413.7;Neutrophil progenitors: 332.1;Respiratory ciliated cells: 315.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - T-cells, Spleen - B-cells (Spleen), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020468, HPA020480, HPA051583" Approved Supported "Golgi apparatus,Plasma membrane,Centriolar satellite,Centrosome,Basal body,Cytosol,Flagellar centriole" NA Yes "Cluster 22: Eosinophils - Transcription" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 6: Non-specific - Immune response" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 5 "Centrosome, Basal body, Flagellar centriole" "Golgi apparatus, Plasma membrane, Centriolar satellite, Cytosol" "HPA020468: , HPA020480: , HPA051583: " "unprognostic (1.81e-3)" "unprognostic (7.84e-2)" "unprognostic (1.06e-1)" "potential prognostic unfavorable (1.59e-4)" "unprognostic (6.66e-3)" "unprognostic (1.19e-1)" "unprognostic (1.61e-2)" "potential prognostic favorable (3.61e-4)" "unprognostic (2.19e-1)" "unprognostic (2.43e-3)" "unprognostic (1.32e-1)" "unprognostic (8.29e-2)" "unprognostic (6.07e-2)" "unprognostic (3.06e-1)" "unprognostic (1.94e-1)" "unprognostic (5.76e-3)" "unprognostic (2.03e-1)" "unprognostic (7.06e-3)" "unprognostic (7.73e-2)" "unprognostic (7.42e-2)" "unprognostic (1.75e-1)" "unprognostic (1.50e-1)" "unprognostic (5.04e-2)" "unprognostic (5.98e-3)" "potential prognostic favorable (8.97e-6)" "unprognostic (3.85e-2)" "unprognostic (4.80e-2)" "unprognostic (3.55e-1)" "unprognostic (1.31e-1)" "unprognostic (1.68e-1)" CNTROB "LIP8, PP1221" ENSG00000170037 "Centrobin, centriole duplication and spindle assembly protein" Q8N137 17 7932101-7949920 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 72.7;Early primary spermatocytes: 49.2;Late primary spermatocytes: 47.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Liver - Vascular endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023319, HPA023320, HPA023321, HPA023325" Approved Supported "Centrosome,Basal body,Cytosol,Flagellar centriole" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 39: Testis - Nuclear processes" "Cluster 6: Non-specific - Immune response" "Cluster 42: Non-specific - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 20 "Centrosome, Basal body, Flagellar centriole" Cytosol "HPA023319: , HPA023320: , HPA023321: , HPA023325: " "unprognostic (2.84e-3)" "unprognostic (1.46e-1)" "unprognostic (7.66e-2)" "unprognostic (1.66e-3)" "unprognostic (1.73e-1)" "unprognostic (2.22e-2)" "unprognostic (9.18e-2)" "unprognostic (9.32e-3)" "unprognostic (1.72e-2)" "unprognostic (8.07e-2)" "unprognostic (2.43e-2)" "unprognostic (3.26e-1)" "unprognostic (5.22e-3)" "unprognostic (7.70e-3)" "unprognostic (1.90e-1)" "unprognostic (3.03e-1)" "unprognostic (6.60e-2)" "unprognostic (1.71e-1)" "unprognostic (1.24e-2)" "unprognostic (3.74e-1)" "unprognostic (4.19e-3)" "unprognostic (2.24e-2)" "unprognostic (1.29e-2)" "unprognostic (2.19e-1)" "unprognostic (1.71e-1)" "unprognostic (2.28e-2)" "unprognostic (1.73e-1)" "unprognostic (1.49e-1)" "unprognostic (9.15e-2)" "unprognostic (2.68e-1)" "unprognostic (1.22e-1)" COA1 "C7orf44, FLJ10803, MITRAC15" ENSG00000106603 "Cytochrome c oxidase assembly factor 1" Q9GZY4 7 43608456-43729717 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Myonuclei: 487.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011944 Approved Supported Mitochondria NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 52: Non-specific - Cellular respiration" "Cluster 31: Non-specific - Transcription" "Cluster 67: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 4 Mitochondria "HPA011944: " "unprognostic (3.38e-1)" "unprognostic (7.16e-3)" "unprognostic (1.24e-1)" "unprognostic (2.80e-1)" "unprognostic (2.28e-1)" "unprognostic (6.36e-3)" "unprognostic (9.16e-2)" "unprognostic (4.66e-3)" "unprognostic (7.54e-3)" "unprognostic (1.57e-2)" "unprognostic (3.22e-1)" "unprognostic (1.95e-1)" "potential prognostic unfavorable (2.49e-5)" "unprognostic (4.58e-3)" "unprognostic (2.75e-2)" "unprognostic (2.69e-2)" "unprognostic (7.83e-2)" "unprognostic (7.37e-2)" "unprognostic (3.57e-1)" "unprognostic (3.59e-2)" "unprognostic (2.91e-3)" "unprognostic (1.79e-1)" "unprognostic (2.44e-2)" "unprognostic (1.04e-2)" "unprognostic (9.01e-3)" "unprognostic (2.22e-1)" "unprognostic (7.45e-2)" "unprognostic (3.92e-1)" "unprognostic (1.67e-1)" COA3 "CCDC56, COX25, hCOA3, HSPC009, MITRAC12" ENSG00000183978 "Cytochrome c oxidase assembly factor 3" Q9Y2R0 17 42795147-42798704 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 383.0;Esophageal apical cells: 567.6;Esophageal basal cells: 386.0;Esophageal suprabasal cells: 706.8;Hepatocytes: 413.5;Parietal cells: 654.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031966, HPA071122" Approved Enhanced Mitochondria NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 72: Kidney - Transmembrane transport" "Cluster 45: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 14 Mitochondria "HPA031966: , HPA071122: " "unprognostic (1.14e-1)" "unprognostic (3.68e-2)" "unprognostic (9.18e-3)" "unprognostic (2.63e-1)" "potential prognostic favorable (9.72e-4)" "unprognostic (9.87e-2)" "unprognostic (2.32e-1)" "unprognostic (2.96e-1)" "unprognostic (1.50e-1)" "potential prognostic favorable (5.16e-4)" "unprognostic (2.30e-3)" "unprognostic (2.82e-2)" "unprognostic (2.94e-3)" "unprognostic (6.87e-2)" "unprognostic (2.28e-1)" "unprognostic (1.23e-3)" "unprognostic (4.62e-2)" "unprognostic (1.51e-2)" "unprognostic (1.39e-2)" "unprognostic (3.79e-3)" "unprognostic (2.57e-1)" "unprognostic (2.87e-2)" "unprognostic (5.51e-2)" "unprognostic (5.76e-2)" "unprognostic (1.19e-1)" "unprognostic (9.09e-2)" "unprognostic (2.03e-1)" "unprognostic (3.60e-2)" "unprognostic (5.84e-2)" COA4 "CHCHD8, CMC3, E2IG2" ENSG00000181924 "Cytochrome c oxidase assembly factor 4 homolog" Q9NYJ1 11 73872667-73876901 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal suprabasal cells: 250.8;Gastric progenitor cells: 261.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040126 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Mitochondria" NA NA 5100 "Cluster 13: Non-specific - Mitochondria" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 2 "Nucleoplasm, Nucleoli fibrillar center" Mitochondria "HPA040126: " "unprognostic (2.70e-1)" "unprognostic (1.16e-1)" "unprognostic (9.76e-2)" "unprognostic (7.03e-2)" "unprognostic (1.29e-1)" "unprognostic (1.73e-1)" "unprognostic (3.29e-2)" "unprognostic (2.58e-3)" "potential prognostic unfavorable (2.27e-4)" "unprognostic (3.21e-2)" "unprognostic (2.49e-1)" "unprognostic (3.85e-2)" "potential prognostic unfavorable (4.37e-4)" "unprognostic (1.69e-3)" "potential prognostic unfavorable (9.47e-4)" "unprognostic (2.82e-1)" "unprognostic (6.57e-2)" "potential prognostic favorable (2.05e-4)" "unprognostic (6.19e-2)" "unprognostic (2.74e-3)" "unprognostic (3.99e-1)" "unprognostic (1.83e-3)" "unprognostic (8.33e-2)" "unprognostic (3.33e-1)" "unprognostic (2.16e-2)" "unprognostic (1.59e-1)" "unprognostic (3.67e-1)" "unprognostic (3.70e-2)" "unprognostic (9.56e-2)" COA5 "C2orf64, FLJ27524, MGC52110, Pet191" ENSG00000183513 "Cytochrome c oxidase assembly factor 5" Q86WW8 2 98599314-98608515 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 147.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057768 Uncertain Supported Mitochondria No No "Cluster 10: Non-specific - Membrane trafficking" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 34: Non-specific - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 97: Non-specific - Cellular respiration" 3 Mitochondria "HPA057768: " "unprognostic (1.86e-3)" "unprognostic (2.46e-2)" "unprognostic (1.87e-1)" "potential prognostic unfavorable (1.53e-4)" "unprognostic (3.32e-2)" "unprognostic (2.25e-2)" "unprognostic (1.68e-2)" "unprognostic (1.10e-1)" "unprognostic (7.28e-2)" "unprognostic (1.20e-2)" "unprognostic (2.69e-3)" "unprognostic (5.15e-2)" "unprognostic (1.20e-2)" "unprognostic (1.66e-1)" "unprognostic (6.02e-2)" "unprognostic (1.06e-3)" "unprognostic (2.48e-3)" "unprognostic (1.68e-2)" "unprognostic (1.65e-2)" "unprognostic (6.43e-2)" "unprognostic (1.97e-2)" "unprognostic (4.73e-2)" "unprognostic (3.24e-2)" "unprognostic (3.07e-3)" "unprognostic (1.52e-1)" "unprognostic (1.66e-2)" "unprognostic (1.03e-1)" "unprognostic (1.20e-1)" "unprognostic (1.53e-1)" COA6 C1orf31 ENSG00000168275 "Cytochrome c oxidase assembly factor 6" Q5JTJ3 1 234373456-234385080 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 150.7;Esophageal suprabasal cells: 137.3;Gastric progenitor cells: 173.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028588 Approved Supported Nucleoplasm,Mitochondria NA NA 10000 "Cluster 33: Non-specific - ATP binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 7: Liver cancer - Metabolism" "Cluster 97: Non-specific - Cellular respiration" 3 Mitochondria Nucleoplasm "HPA028588: " "unprognostic (1.49e-2)" "unprognostic (2.52e-1)" "unprognostic (2.17e-1)" "unprognostic (2.02e-1)" "unprognostic (2.85e-1)" "potential prognostic unfavorable (7.70e-4)" "unprognostic (5.33e-1)" "potential prognostic unfavorable (6.01e-4)" "unprognostic (1.09e-2)" "unprognostic (1.30e-3)" "unprognostic (1.13e-3)" "potential prognostic unfavorable (1.88e-4)" "unprognostic (2.43e-3)" "potential prognostic unfavorable (1.38e-5)" "unprognostic (4.11e-2)" "unprognostic (6.27e-2)" "unprognostic (8.90e-2)" "unprognostic (1.45e-2)" "unprognostic (1.15e-1)" "unprognostic (1.42e-1)" "unprognostic (8.17e-3)" "unprognostic (9.72e-2)" "unprognostic (1.72e-1)" "unprognostic (4.98e-2)" "unprognostic (1.12e-2)" "unprognostic (1.79e-1)" "unprognostic (4.00e-2)" "unprognostic (1.29e-1)" "unprognostic (1.70e-1)" COA7 "C1orf163, FLJ12439, RESA1, SELRC1" ENSG00000162377 "Cytochrome c oxidase assembly factor 7" Q96BR5 1 52684449-52698347 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028154, HPA029926" Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 35 "Nucleoplasm, Mitochondria" "HPA028154: , HPA029926: " "unprognostic (5.02e-2)" "unprognostic (9.85e-2)" "unprognostic (3.15e-3)" "unprognostic (1.44e-2)" "unprognostic (3.36e-1)" "unprognostic (2.10e-2)" "unprognostic (2.77e-2)" "unprognostic (1.23e-1)" "unprognostic (2.44e-2)" "unprognostic (1.11e-3)" "unprognostic (3.71e-2)" "unprognostic (3.08e-2)" "potential prognostic unfavorable (1.13e-5)" "potential prognostic unfavorable (5.79e-4)" "unprognostic (1.59e-2)" "unprognostic (1.36e-1)" "unprognostic (5.79e-2)" "unprognostic (8.05e-2)" "unprognostic (5.28e-2)" "unprognostic (3.59e-3)" "unprognostic (6.96e-2)" "unprognostic (1.28e-3)" "unprognostic (8.26e-2)" "unprognostic (2.16e-1)" "unprognostic (1.16e-2)" "unprognostic (3.54e-2)" "unprognostic (1.08e-1)" "unprognostic (6.78e-2)" "unprognostic (3.21e-1)" COA8 "APOP-1, APOPT1, C14orf153, MGC2562" ENSG00000256053 "Cytochrome c oxidase assembly factor 8" Q96IL0 14 103562960-103607523 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Apoptosis "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 114.3" "Cell type enhanced" "Detected in many" "Early spermatids: 285.1;Late primary spermatocytes: 116.3;Late spermatids: 574.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 32: Basophils - Transcription" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 30: White matter - Myelination" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 2 "unprognostic (2.31e-1)" "unprognostic (2.32e-1)" "unprognostic (2.68e-2)" "unprognostic (2.11e-1)" "unprognostic (4.81e-2)" "unprognostic (3.62e-2)" "potential prognostic unfavorable (4.07e-4)" "unprognostic (7.28e-3)" "unprognostic (9.12e-2)" "unprognostic (6.68e-2)" "unprognostic (5.20e-2)" "unprognostic (2.27e-2)" "potential prognostic unfavorable (3.25e-9)" "unprognostic (6.95e-3)" "unprognostic (2.75e-2)" "unprognostic (8.65e-2)" "unprognostic (9.91e-3)" "unprognostic (1.07e-2)" "unprognostic (2.35e-3)" "unprognostic (2.20e-2)" "unprognostic (4.83e-2)" "unprognostic (4.25e-1)" "unprognostic (3.52e-1)" "unprognostic (9.25e-2)" "unprognostic (1.43e-1)" "unprognostic (1.14e-1)" "unprognostic (2.08e-1)" "unprognostic (1.48e-1)" "unprognostic (4.80e-2)" COASY "DPCK, NBP, PPAT" ENSG00000068120 "Coenzyme A synthase" Q13057 17 42561467-42566277 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Coenzyme A biosynthesis" "Kinase, Multifunctional enzyme, Nucleotidyltransferase, Transferase" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 104.8;Cytotrophoblasts: 105.9;Hepatocytes: 115.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022875, HPA022912, HPA023273" Approved Supported "Mitochondria,Connecting piece" "Intracellular and membrane" Enzyme NA NA 35000 "Cluster 33: Non-specific - ATP binding" "Cluster 70: Non-specific - Protein processing" "Cluster 45: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 9 Mitochondria "Connecting piece" "HPA022875: , HPA022912: , HPA023273: " "unprognostic (2.13e-1)" "unprognostic (7.95e-2)" "unprognostic (1.04e-1)" "unprognostic (7.23e-3)" "unprognostic (3.85e-1)" "unprognostic (5.00e-1)" "unprognostic (2.89e-2)" "unprognostic (1.63e-1)" "unprognostic (4.82e-3)" "unprognostic (2.80e-3)" "unprognostic (1.07e-2)" "unprognostic (1.81e-1)" "unprognostic (9.34e-2)" "validated prognostic unfavorable (5.21e-4)" "validated prognostic unfavorable (1.44e-5)" "potential prognostic unfavorable (6.61e-4)" "unprognostic (4.26e-2)" "unprognostic (3.43e-2)" "unprognostic (4.35e-1)" "unprognostic (2.36e-2)" "unprognostic (8.56e-2)" "unprognostic (6.80e-2)" "unprognostic (3.75e-2)" "unprognostic (6.97e-2)" "unprognostic (1.63e-3)" "unprognostic (1.65e-1)" "unprognostic (1.38e-1)" "unprognostic (2.77e-1)" "unprognostic (3.17e-1)" "unprognostic (1.06e-1)" "unprognostic (3.36e-3)" COBL KIAA0633 ENSG00000106078 "Cordon-bleu WH2 repeat protein" O75128 7 51016212-51316818 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 124.0;tongue: 100.7" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 562.0;Epicardial cells: 784.6;Oligodendrocyte progenitor cells: 617.5;Oligodendrocytes: 680.6;Prostatic glandular cells: 706.5;Salivary acinar cells: 701.7" "Cell type enhanced" "Detected in all" "oligodendrocyte: 771.7;oligodendrocyte precursor cell: 732.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 14 "plasmacytoid DC: 1.3" "Lineage enriched" "Detected in single" 14 "dendritic cells: 1.3" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Lung - Alveolar cells type 1, Pituitary gland - Corticotropes, Prostate - Prostate glandular cells, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019033, HPA019167" Enhanced Approved "Plasma membrane,Cell Junctions" NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 15: Kidney cancer - Membrane components" "Cluster 51: Secretory epithelial cells - Mixed function" 14 "Plasma membrane, Cell Junctions" "HPA019033: , HPA019167: " "unprognostic (1.65e-3)" "unprognostic (1.93e-1)" "unprognostic (2.38e-1)" "unprognostic (9.36e-3)" "unprognostic (1.72e-1)" "unprognostic (4.01e-3)" "unprognostic (1.49e-1)" "unprognostic (1.04e-2)" "unprognostic (3.34e-3)" "unprognostic (5.52e-2)" "validated prognostic favorable (1.21e-9)" "validated prognostic favorable (1.44e-5)" "potential prognostic favorable (3.42e-5)" "unprognostic (1.50e-1)" "unprognostic (3.95e-2)" "unprognostic (1.24e-3)" "unprognostic (1.63e-1)" "unprognostic (1.66e-2)" "unprognostic (8.21e-2)" "unprognostic (7.70e-2)" "unprognostic (4.53e-1)" "unprognostic (1.48e-1)" "unprognostic (1.52e-1)" "unprognostic (2.20e-1)" "unprognostic (5.55e-2)" "unprognostic (3.56e-1)" "unprognostic (3.84e-2)" "unprognostic (1.60e-1)" "unprognostic (5.26e-1)" "unprognostic (3.12e-1)" "unprognostic (3.13e-1)" COBLL1 KIAA0977 ENSG00000082438 "Cordon-bleu WH2 repeat protein like 1" Q53SF7 2 164653624-164843679 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 100.6" "Cell type enhanced" "Detected in many" "Adipocytes: 1028.6;Distal convoluted tubule cells: 2406.5;Loop of henle epithelial cells: 1534.0;Papillary tip epithelial cells: 1006.4;Renal collecting duct intercalated cells: 1626.8;Renal collecting duct principal cells: 1811.1;Renal connecting tubule cells: 3322.1;Syncytiotrophoblasts: 1496.7" "Group enriched" "Detected in many" 5 "choroid plexus epithelial cell: 871.4;endothelial cell: 2638.0;fibroblast: 837.8;pericyte: 1684.9;vascular associated smooth muscle cell: 1048.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "memory B-cell: 15.0;naive B-cell: 9.5;plasmacytoid DC: 8.2" "Group enriched" "Detected in many" 13 "B-cells: 15.0;dendritic cells: 8.2" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044933, HPA053344" Enhanced Approved "Cell Junctions" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 76: Non-specific - Metabolism" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 15: Kidney cancer - Membrane components" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 21 "Cell Junctions" "HPA044933: , HPA053344: " "unprognostic (2.14e-1)" "unprognostic (9.75e-2)" "unprognostic (3.51e-2)" "unprognostic (7.12e-2)" "unprognostic (1.35e-1)" "unprognostic (1.94e-1)" "unprognostic (2.16e-2)" "unprognostic (4.90e-2)" "unprognostic (3.12e-1)" "unprognostic (1.82e-1)" "potential prognostic favorable (3.43e-8)" "unprognostic (1.15e-3)" "unprognostic (3.43e-2)" "unprognostic (5.56e-3)" "potential prognostic favorable (4.41e-4)" "unprognostic (9.53e-3)" "unprognostic (2.32e-2)" "unprognostic (2.59e-1)" "unprognostic (4.04e-1)" "unprognostic (1.41e-1)" "unprognostic (6.57e-2)" "unprognostic (1.29e-2)" "unprognostic (3.98e-2)" "unprognostic (1.18e-1)" "unprognostic (4.25e-2)" "unprognostic (1.20e-1)" "unprognostic (2.26e-1)" "unprognostic (7.48e-2)" "unprognostic (1.19e-1)" "unprognostic (3.24e-1)" "potential prognostic unfavorable (6.97e-6)" COCH "COCH-5B2, DFNA31, DFNA9" ENSG00000100473 Cochlin O43405 14 30874514-30895065 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" Hearing "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "pancreas: 473.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 100.0;Brain inhibitory neurons: 144.0;Epididymal clear cells: 130.6" "Cell type enriched" "Detected in all" 5 "medium spiny neuron: 282.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "basal ganglia: 151.3" "Group enriched" "Detected in some" 12 "memory B-cell: 38.4;naive B-cell: 17.8" "Lineage enriched" "Detected in many" 17 "B-cells: 38.4" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "amygdala: 23.2;basal ganglia: 66.7;cerebral cortex: 17.2;hippocampal formation: 16.6" HPA065086 Approved Vesicles "Secreted in other tissues" Other NA NA 480000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 8: Pancreas - Proteolysis" "Cluster 33: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 1 Vesicles "HPA065086: " "unprognostic (3.15e-1)" "unprognostic (7.00e-2)" "unprognostic (7.99e-2)" "unprognostic (3.04e-2)" "unprognostic (1.27e-1)" "unprognostic (3.57e-3)" "unprognostic (4.33e-2)" "unprognostic (2.60e-1)" "unprognostic (9.70e-2)" "unprognostic (1.71e-1)" "unprognostic (1.77e-3)" "unprognostic (2.80e-2)" "unprognostic (3.01e-2)" "unprognostic (1.11e-1)" "unprognostic (2.27e-2)" "unprognostic (2.43e-2)" "unprognostic (2.34e-1)" "unprognostic (1.90e-2)" "unprognostic (1.77e-3)" "unprognostic (1.58e-1)" "unprognostic (4.20e-2)" "unprognostic (1.56e-2)" "unprognostic (1.71e-1)" "unprognostic (6.18e-3)" "unprognostic (6.71e-2)" "unprognostic (1.94e-1)" "unprognostic (2.74e-1)" "unprognostic (8.91e-3)" "unprognostic (1.36e-2)" "unprognostic (5.84e-2)" COG1 "KIAA1381, LDLB" ENSG00000166685 "Component of oligomeric golgi complex 1" Q8WTW3 17 73193055-73208507 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Congenital disorder of glycosylation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029224 Approved NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 51: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" 20 "HPA029224: " "unprognostic (2.22e-1)" "unprognostic (2.06e-1)" "unprognostic (1.97e-2)" "unprognostic (1.92e-1)" "unprognostic (3.65e-3)" "unprognostic (3.78e-2)" "unprognostic (1.24e-1)" "unprognostic (2.78e-1)" "potential prognostic unfavorable (9.71e-5)" "unprognostic (9.17e-2)" "unprognostic (3.73e-1)" "unprognostic (2.32e-2)" "unprognostic (2.19e-1)" "potential prognostic unfavorable (5.96e-5)" "unprognostic (1.93e-2)" "unprognostic (2.74e-2)" "unprognostic (1.82e-1)" "unprognostic (2.37e-1)" "unprognostic (2.45e-1)" "unprognostic (2.42e-3)" "unprognostic (1.75e-1)" "unprognostic (4.88e-3)" "unprognostic (5.97e-3)" "unprognostic (7.63e-2)" "unprognostic (4.94e-2)" "unprognostic (1.57e-1)" "unprognostic (7.14e-2)" "unprognostic (1.94e-1)" "unprognostic (1.34e-1)" "unprognostic (2.45e-1)" "unprognostic (7.26e-2)" COG2 LDLC ENSG00000135775 "Component of oligomeric golgi complex 2" Q14746 1 230642481-230693982 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 66.9" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076994 Approved "Golgi apparatus" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 55: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 70: Intestinal goblet cells - Mucin production" 25 "Golgi apparatus" "HPA076994: " "unprognostic (2.28e-2)" "unprognostic (5.77e-2)" "unprognostic (1.45e-1)" "unprognostic (2.75e-1)" "unprognostic (1.35e-3)" "unprognostic (7.69e-3)" "potential prognostic favorable (4.34e-4)" "unprognostic (1.08e-2)" "unprognostic (9.36e-2)" "unprognostic (3.07e-2)" "potential prognostic favorable (9.10e-5)" "unprognostic (4.76e-2)" "unprognostic (8.32e-2)" "unprognostic (4.23e-2)" "unprognostic (3.32e-3)" "unprognostic (6.18e-2)" "unprognostic (3.75e-1)" "unprognostic (1.59e-1)" "unprognostic (4.87e-2)" "unprognostic (2.64e-1)" "unprognostic (2.57e-1)" "unprognostic (3.13e-1)" "unprognostic (8.47e-2)" "unprognostic (1.21e-1)" "unprognostic (1.19e-1)" "unprognostic (1.30e-1)" "unprognostic (4.22e-2)" "unprognostic (1.37e-1)" "unprognostic (4.82e-2)" "unprognostic (5.45e-2)" "unprognostic (2.16e-1)" COG3 SEC34 ENSG00000136152 "Component of oligomeric golgi complex 3" Q96JB2 13 45464898-45536701 "Essential proteins, Predicted intracellular proteins" "Protein transport, Transport" "Congenital disorder of glycosylation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040353, HPA054470" Approved Supported "Nucleoplasm,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 31: Non-specific - Transcription" "Cluster 19: Non-specific - Unknown function" "Cluster 8: Non-specific - Secretory pathway" 22 "Golgi apparatus, Plasma membrane" "Nucleoplasm, Cytosol" "HPA040353: , HPA054470: " "unprognostic (2.80e-2)" "unprognostic (1.88e-2)" "unprognostic (2.40e-1)" "potential prognostic unfavorable (4.29e-4)" "unprognostic (1.08e-1)" "unprognostic (2.63e-1)" "unprognostic (1.09e-1)" "unprognostic (8.97e-2)" "unprognostic (1.43e-1)" "unprognostic (7.85e-2)" "potential prognostic favorable (2.37e-5)" "unprognostic (4.00e-3)" "unprognostic (1.12e-1)" "unprognostic (1.78e-2)" "unprognostic (5.86e-2)" "unprognostic (1.47e-2)" "unprognostic (5.16e-2)" "unprognostic (2.19e-1)" "unprognostic (7.96e-2)" "unprognostic (1.66e-2)" "unprognostic (1.93e-2)" "unprognostic (2.34e-1)" "unprognostic (2.10e-2)" "unprognostic (6.89e-2)" "unprognostic (5.96e-2)" "unprognostic (1.27e-1)" "unprognostic (4.05e-2)" "unprognostic (3.37e-2)" "unprognostic (9.75e-2)" "unprognostic (1.51e-1)" "unprognostic (3.92e-2)" COG4 "COD1, DKFZP586E1519" ENSG00000103051 "Component of oligomeric golgi complex 4" 16 70480568-70523560 "Essential proteins, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Mitotic cells (Minor salivary gland)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040924, HPA042539" Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Transcription" 7 "Golgi apparatus" Vesicles "HPA040924: , HPA042539: " "unprognostic (1.22e-1)" "unprognostic (5.20e-2)" "unprognostic (1.52e-1)" "unprognostic (7.95e-2)" "unprognostic (9.13e-2)" "unprognostic (1.69e-1)" "unprognostic (4.06e-2)" "potential prognostic favorable (1.62e-5)" "unprognostic (1.74e-2)" "unprognostic (1.09e-1)" "unprognostic (1.51e-3)" "unprognostic (4.56e-1)" "unprognostic (2.22e-3)" "potential prognostic unfavorable (8.14e-7)" "unprognostic (1.02e-1)" "unprognostic (4.07e-2)" "unprognostic (8.81e-3)" "unprognostic (8.95e-2)" "unprognostic (5.44e-2)" "unprognostic (1.05e-1)" "unprognostic (4.33e-2)" "unprognostic (1.67e-1)" "unprognostic (2.94e-2)" "unprognostic (1.79e-1)" "unprognostic (5.95e-1)" "unprognostic (9.61e-3)" "unprognostic (1.67e-1)" "unprognostic (2.80e-1)" "unprognostic (9.03e-2)" "unprognostic (2.23e-1)" "unprognostic (5.64e-2)" COG5 "GOLTC1, GTC90" ENSG00000164597 "Component of oligomeric golgi complex 5" Q9UP83 7 107201372-107564261 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Congenital disorder of glycosylation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 202.6;Bergmann glia: 182.8;Brain excitatory neurons: 185.7;Brain inhibitory neurons: 190.5;Choroid plexus epithelial cells: 325.7;Distal convoluted tubule cells: 234.8;Ependymal cells: 148.6;Loop of henle epithelial cells: 179.2;Microglia: 315.5;Oligodendrocyte progenitor cells: 193.4;Oligodendrocytes: 212.1;Other brain neurons: 151.5;Papillary tip epithelial cells: 207.7;Podocytes: 225.8;Proximal tubule cells: 166.7;Renal collecting duct intercalated cells: 345.9;Renal collecting duct principal cells: 222.7;Renal connecting tubule cells: 233.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020300, HPA041583" Uncertain Enhanced "Nucleoplasm,Golgi apparatus" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 82: Salivary gland - Secretion" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 39: Non-specific - Transcription" "Cluster 102: Non-specific - Mixed function" 9 "Golgi apparatus" Nucleoplasm "HPA020300: , HPA041583: " "unprognostic (9.13e-3)" "unprognostic (9.85e-2)" "unprognostic (2.48e-1)" "unprognostic (4.20e-1)" "unprognostic (4.27e-2)" "unprognostic (4.43e-2)" "unprognostic (2.58e-1)" "unprognostic (1.04e-1)" "unprognostic (7.40e-2)" "unprognostic (4.81e-3)" "potential prognostic favorable (1.00e-4)" "unprognostic (9.95e-2)" "unprognostic (3.77e-1)" "potential prognostic unfavorable (4.47e-4)" "unprognostic (3.28e-3)" "unprognostic (1.29e-1)" "unprognostic (1.04e-1)" "unprognostic (3.34e-2)" "unprognostic (2.18e-2)" "unprognostic (1.45e-2)" "unprognostic (3.11e-3)" "unprognostic (5.70e-2)" "unprognostic (1.46e-1)" "unprognostic (3.44e-1)" "unprognostic (3.74e-1)" "unprognostic (2.26e-2)" "unprognostic (9.06e-2)" "unprognostic (1.10e-2)" "unprognostic (4.32e-2)" "unprognostic (5.03e-3)" "unprognostic (2.13e-1)" COG6 "COD2, KIAA1134" ENSG00000133103 "Component of oligomeric golgi complex 6" Q9Y2V7 13 39655627-39791665 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Congenital disorder of glycosylation, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Lactotrophs: 245.4;Somatotrophs: 254.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040410, HPA040441" Uncertain Approved "Nuclear speckles,Golgi apparatus" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 19: Non-specific - Unknown function" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 62 "Nuclear speckles, Golgi apparatus" "HPA040410: , HPA040441: " "unprognostic (9.60e-2)" "unprognostic (3.11e-1)" "unprognostic (2.43e-2)" "unprognostic (5.87e-3)" "unprognostic (1.37e-1)" "unprognostic (7.32e-2)" "unprognostic (3.10e-1)" "unprognostic (1.41e-1)" "unprognostic (1.07e-1)" "unprognostic (9.25e-2)" "potential prognostic favorable (8.88e-10)" "unprognostic (1.71e-2)" "unprognostic (1.75e-1)" "unprognostic (9.66e-2)" "unprognostic (3.70e-2)" "unprognostic (7.71e-2)" "unprognostic (1.86e-1)" "unprognostic (1.46e-1)" "unprognostic (2.07e-1)" "unprognostic (9.45e-2)" "potential prognostic unfavorable (3.74e-4)" "unprognostic (1.11e-1)" "unprognostic (1.66e-3)" "unprognostic (3.63e-1)" "unprognostic (2.50e-2)" "unprognostic (3.53e-2)" "unprognostic (4.95e-2)" "unprognostic (2.68e-2)" "unprognostic (1.46e-1)" "unprognostic (1.66e-1)" "unprognostic (6.30e-2)" COG7 ENSG00000168434 "Component of oligomeric golgi complex 7" P83436 16 23388493-23453189 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Congenital disorder of glycosylation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040758, HPA041824, HPA064645" Uncertain Supported "Golgi apparatus" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 20: Pituitary gland - Hormone signaling" "Cluster 36: Choroid plexus - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 30 "Golgi apparatus" "HPA040758: , HPA041824: , HPA064645: " "unprognostic (2.35e-2)" "unprognostic (4.13e-2)" "unprognostic (1.57e-1)" "unprognostic (4.10e-1)" "unprognostic (1.25e-1)" "unprognostic (4.70e-2)" "unprognostic (1.40e-1)" "unprognostic (1.54e-2)" "unprognostic (1.34e-1)" "unprognostic (3.47e-2)" "potential prognostic favorable (4.47e-6)" "unprognostic (2.50e-1)" "unprognostic (8.71e-2)" "unprognostic (1.50e-2)" "unprognostic (1.24e-1)" "unprognostic (2.84e-2)" "unprognostic (1.49e-1)" "unprognostic (5.52e-2)" "unprognostic (1.43e-1)" "unprognostic (1.07e-1)" "unprognostic (2.48e-1)" "unprognostic (2.59e-1)" "potential prognostic unfavorable (1.31e-4)" "unprognostic (2.65e-1)" "unprognostic (1.01e-2)" "unprognostic (3.10e-1)" "unprognostic (2.77e-1)" "unprognostic (2.05e-1)" "unprognostic (1.30e-1)" "unprognostic (3.53e-2)" "unprognostic (1.22e-2)" COG8 "DOR1, FLJ22315" ENSG00000213380 "Component of oligomeric golgi complex 8" Q96MW5 16 69320140-69339583 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Congenital disorder of glycosylation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 43.4;Epicardial cells: 52.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041406, HPA049429" Approved Supported "Golgi apparatus" No No "Cluster 33: Non-specific - ATP binding" "Cluster 21: Testis - Mixed function" "Cluster 25: Non-specific - Transcription" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 22 "Golgi apparatus" "HPA041406: , HPA049429: " "unprognostic (9.26e-2)" "unprognostic (1.98e-2)" "unprognostic (3.76e-1)" "unprognostic (6.89e-3)" "unprognostic (1.69e-1)" "unprognostic (2.96e-1)" "unprognostic (2.51e-1)" "potential prognostic favorable (3.51e-5)" "unprognostic (2.21e-1)" "unprognostic (9.37e-2)" "potential prognostic favorable (2.26e-5)" "unprognostic (1.29e-2)" "potential prognostic favorable (4.15e-4)" "unprognostic (3.27e-2)" "unprognostic (1.11e-1)" "unprognostic (5.46e-2)" "unprognostic (5.39e-3)" "unprognostic (2.09e-2)" "unprognostic (1.84e-2)" "unprognostic (5.03e-1)" "unprognostic (5.30e-2)" "potential prognostic favorable (8.52e-4)" "unprognostic (1.13e-1)" "unprognostic (4.30e-1)" "unprognostic (1.85e-2)" "unprognostic (3.24e-1)" "unprognostic (1.35e-1)" "unprognostic (2.10e-1)" "unprognostic (4.47e-1)" "unprognostic (1.95e-2)" "unprognostic (8.76e-2)" COIL "CLN80, p80-coilin" ENSG00000121058 Coilin P38432 17 56938199-56961050 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "testis: 92.1" "Cell type enhanced" "Detected in many" "Early spermatids: 223.7;Late primary spermatocytes: 267.2;Late spermatids: 905.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017524, HPA027885, HPA068537, CAB069400" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Nuclear bodies" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 57: Testis - Spermatogenesis" "Cluster 31: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 109 "Nuclear bodies" "Nucleoplasm, Nucleoli fibrillar center" "CAB017524: , CAB069400: , HPA027885: , HPA068537: " "unprognostic (3.64e-2)" "unprognostic (1.69e-2)" "unprognostic (1.66e-1)" "unprognostic (9.47e-3)" "unprognostic (3.55e-2)" "unprognostic (1.26e-2)" "unprognostic (4.25e-2)" "unprognostic (8.36e-3)" "unprognostic (3.30e-2)" "unprognostic (1.23e-3)" "unprognostic (4.05e-3)" "unprognostic (4.24e-2)" "unprognostic (4.90e-2)" "potential prognostic unfavorable (4.17e-4)" "unprognostic (1.32e-3)" "unprognostic (5.49e-2)" "unprognostic (2.89e-3)" "unprognostic (2.63e-1)" "unprognostic (4.61e-3)" "unprognostic (5.94e-3)" "unprognostic (1.22e-1)" "unprognostic (5.77e-2)" "unprognostic (6.60e-3)" "unprognostic (2.02e-2)" "unprognostic (7.14e-3)" "unprognostic (7.05e-2)" "potential prognostic unfavorable (2.84e-4)" "unprognostic (5.45e-2)" "unprognostic (3.38e-1)" "unprognostic (3.51e-1)" "unprognostic (2.83e-2)" COL10A1 ENSG00000123500 "Collagen type X alpha 1 chain" Q03692 6 116118909-116158747 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "gallbladder: 8.3;ovary: 5.5" "Cell type enhanced" "Detected in many" "Adipocytes: 111.4;Cardiomyocytes: 587.1;Epicardial cells: 152.4;Myonuclei: 100.4" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 100.5;oligodendrocyte: 59.2" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 173.5;Pancreatic Adenocarcinoma (TCGA): 175.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 2.9;thyroid cancer: 3.3" "Skin - Outer root sheath cells" "Low region specificity" "Detected in many" HPA053268 Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" "No annotated function" NA NA 62000 "Cluster 55: Breast - Lactation" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 72: Neuronal - Signal transduction" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 17 "Endoplasmic reticulum" "HPA053268: " "unprognostic (8.27e-3)" "unprognostic (7.59e-2)" "unprognostic (5.75e-2)" "unprognostic (4.53e-2)" "unprognostic (1.43e-2)" "unprognostic (2.79e-3)" "unprognostic (4.26e-3)" "unprognostic (2.73e-2)" "unprognostic (4.06e-2)" "unprognostic (1.04e-3)" "unprognostic (1.14e-1)" "unprognostic (1.06e-1)" "unprognostic (3.44e-1)" "unprognostic (2.42e-1)" "unprognostic (3.79e-2)" "unprognostic (8.13e-2)" "unprognostic (1.46e-1)" "unprognostic (9.58e-3)" "potential prognostic unfavorable (4.34e-6)" "unprognostic (4.50e-2)" "unprognostic (4.15e-2)" "unprognostic (1.52e-1)" "unprognostic (6.45e-2)" "unprognostic (2.62e-2)" "unprognostic (3.31e-1)" "unprognostic (4.53e-3)" "unprognostic (1.04e-1)" "unprognostic (3.43e-1)" "unprognostic (1.51e-2)" COL11A1 "CO11A1, COLL6, DFNA37, STL2" ENSG00000060718 "Collagen type XI alpha 1 chain" P12107 1 102876467-103108872 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Cataract, Deafness, Disease variant, Dwarfism, Ectodermal dysplasia, Non-syndromic deafness, Stickler syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 18.9;retina: 8.9" "Cell type enhanced" "Detected in many" "Astrocytes: 91.8;Brain inhibitory neurons: 90.1;Müller glia: 99.1;Oligodendrocyte progenitor cells: 684.0;Oligodendrocytes: 161.0;Pituicytes/FSCs: 432.5;Pituitary stem cells: 202.4;Retinal amacrine cells: 159.6" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 855.2;oligodendrocyte precursor cell: 815.0" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 32.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 252.9" "Adrenal gland - Adrenal cortex cells, Colon - Enteric glia cells, Lung - Alveolar cells type 2, Minor Salivary Gland - Smooth muscle cells, Skeletal muscle - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA058335 Supported "Endoplasmic reticulum" "Secreted to extracellular matrix" "No annotated function" No No 540000 "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 53: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" "Endoplasmic reticulum" "HPA058335: " "unprognostic (1.45e-1)" "unprognostic (3.12e-2)" "unprognostic (2.63e-2)" "unprognostic (2.43e-2)" "unprognostic (5.19e-2)" "unprognostic (1.12e-1)" "unprognostic (1.83e-1)" "unprognostic (1.41e-2)" "unprognostic (3.03e-2)" "potential prognostic unfavorable (3.28e-5)" "unprognostic (2.77e-2)" "unprognostic (3.20e-1)" "potential prognostic unfavorable (5.84e-4)" "unprognostic (2.31e-3)" "unprognostic (2.51e-1)" "unprognostic (5.67e-2)" "unprognostic (5.11e-2)" "potential prognostic unfavorable (7.66e-8)" "unprognostic (5.75e-3)" "unprognostic (4.28e-1)" "unprognostic (3.56e-1)" "unprognostic (1.62e-2)" "unprognostic (7.39e-2)" "unprognostic (1.14e-2)" "unprognostic (6.45e-2)" "unprognostic (1.57e-2)" COL11A2 "DFNA13, DFNB53, HKE5" ENSG00000204248 "Collagen type XI alpha 2 chain" P13942 6 33162681-33192499 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Deafness, Disease variant, Dwarfism, Non-syndromic deafness, Stickler syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 14.2;pituitary gland: 21.9;testis: 7.6" "Cell type enhanced" "Detected in some" "Astrocytes: 6.0;Bergmann glia: 4.7;Brain excitatory neurons: 5.5;Brain inhibitory neurons: 5.5;Ependymal cells: 2.4;Oligodendrocyte progenitor cells: 7.4;Oligodendrocytes: 7.0;Other brain neurons: 2.8;Pituitary stem cells: 9.7;Retinal amacrine cells: 2.1;Retinal horizontal cells: 2.0" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in single" 9 "Skin Cutaneous Melanoma (TCGA): 5.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bone cancer: 2.7;skin cancer: 1.7" "Colon - Enteric glia cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" "No annotated function" NA NA 5200000 "Cluster 71: Cerebellum - Nervous system development" "Cluster 6: Non-specific - Immune response" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" 1 "unprognostic (8.47e-2)" "unprognostic (1.92e-2)" "unprognostic (9.16e-3)" "unprognostic (2.58e-2)" "unprognostic (4.21e-2)" COL12A1 COL12A1L ENSG00000111799 "Collagen type XII alpha 1 chain" Q99715 6 75084326-75206267 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Congenital muscular dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 103.2" "Cell type enhanced" "Detected in many" "Adipocytes: 114.4;Alveolar cells type 1: 328.0;Endometrial secretory cells: 105.7;Endometrial stromal cells: 217.3;Fibro-adipogenic progenitors: 483.9;Fibroblasts: 256.5;Hepatic stellate cells: 129.1;Leydig cells: 110.7;Ovarian stromal cells: 139.6;Schwann cells: 142.6;Smooth muscle cells: 157.4" "Cell type enhanced" "Detected in many" "deep-layer near-projecting: 409.1;fibroblast: 393.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Smooth muscle cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 39.2" "HPA009143, HPA010021" Uncertain Approved Vesicles,Cytosol "Secreted to extracellular matrix" "Cell adhesion" NA NA 14000000 "Cluster 75: Ovary - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" Vesicles Cytosol "HPA009143: , HPA010021: " "unprognostic (2.94e-2)" "unprognostic (4.47e-2)" "unprognostic (2.22e-2)" "unprognostic (1.65e-2)" "unprognostic (1.66e-1)" "unprognostic (3.46e-1)" "unprognostic (1.73e-2)" "unprognostic (4.18e-1)" "unprognostic (1.38e-1)" "unprognostic (2.36e-3)" "unprognostic (2.26e-1)" "unprognostic (4.44e-1)" "potential prognostic unfavorable (7.81e-7)" "unprognostic (2.73e-2)" "unprognostic (2.29e-1)" "unprognostic (3.42e-3)" "unprognostic (4.40e-3)" "unprognostic (3.18e-1)" "unprognostic (6.21e-2)" "unprognostic (3.92e-2)" "unprognostic (2.25e-2)" "unprognostic (5.05e-3)" "unprognostic (1.10e-1)" "unprognostic (1.40e-1)" "unprognostic (3.26e-1)" "unprognostic (6.02e-3)" "unprognostic (6.64e-2)" "unprognostic (2.19e-3)" "unprognostic (1.24e-1)" "unprognostic (2.26e-3)" "unprognostic (8.62e-2)" COL13A1 ENSG00000197467 "Collagen type XIII alpha 1 chain" Q5TAT6 10 69801880-69964275 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Differentiation, Osteogenesis" "Developmental protein, Heparin-binding" "Congenital myasthenic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 18.3;brain: 28.2;epididymis: 18.8" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 21.2;Breast myoepithelial cells: 12.1;Epididymal basal cells: 20.9;Epididymal principal cells: 42.3;Fibroblasts: 20.1;Mast cells: 69.9;Myonuclei: 29.6;Pituicytes/FSCs: 16.4;Tuft cells: 23.1;Vascular endothelial cells: 15.0;Vascular smooth muscle cells: 20.6" "Cell type enhanced" "Detected in some" "fibroblast: 146.6;upper rhombic lip: 59.8" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 9 "cerebellum: 10.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 23.6" "Liver - Hepatic stellate cells, Lung - Fibroblasts_1, Pituitary gland - Fibroblasts, Prostate - Fibroblasts, Spleen - Fibroblasts_2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA050392 Approved NA NA "Cluster 64: Non-specific - Transcription" "Cluster 35: Non-specific - DNA binding" "Cluster 72: Neuronal - Signal transduction" "Cluster 46: Skeletal myocytes - Muscle structure & formation" "HPA050392: " "unprognostic (2.09e-1)" "unprognostic (1.46e-2)" "unprognostic (2.11e-1)" "unprognostic (2.27e-1)" "unprognostic (1.48e-1)" "unprognostic (2.82e-1)" "potential prognostic unfavorable (1.29e-4)" "unprognostic (5.51e-2)" "unprognostic (6.70e-2)" "unprognostic (1.05e-1)" "potential prognostic favorable (8.39e-4)" "unprognostic (1.04e-1)" "unprognostic (1.78e-2)" "unprognostic (5.77e-2)" "unprognostic (2.14e-1)" "unprognostic (8.21e-2)" "unprognostic (3.70e-3)" "unprognostic (1.26e-1)" "potential prognostic unfavorable (9.81e-5)" "unprognostic (1.48e-2)" "unprognostic (5.84e-1)" "unprognostic (1.96e-1)" "unprognostic (5.64e-2)" "unprognostic (2.65e-1)" "unprognostic (7.72e-2)" "unprognostic (2.51e-2)" "unprognostic (6.08e-2)" COL14A1 UND ENSG00000187955 "Collagen type XIV alpha 1 chain" Q05707 8 120059780-120373573 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 256.6" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 125.4;Fibro-adipogenic progenitors: 159.1;Fibroblasts: 271.6;Granulosa cells: 146.8;Hepatic stellate cells: 529.3;Pericytes: 189.2;Vascular smooth muscle cells: 343.8" "Cell type enriched" "Detected in many" 6 "vascular associated smooth muscle cell: 413.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "Brain cancer: 24.1;colorectal cancer: 18.5;Sarcoma: 48.6;thyroid cancer: 18.0" "Adipose visceral - Adipose progenitor cells, Adrenal gland - Fibroblasts, Breast - Fibroblasts, Colon - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblasts_2, Minor Salivary Gland - Fibroblasts, Prostate - Fibroblasts, Skin - Fibroblasts_1, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Testis - Peritubular cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA023781 Uncertain Approved Vesicles "Secreted to extracellular matrix" "Cell adhesion" NA NA 6100000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 43: Hindbrain - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 108: Fibroblasts - ECM organization" 1 Vesicles "HPA023781: " "unprognostic (3.95e-2)" "unprognostic (4.05e-2)" "unprognostic (1.03e-2)" "unprognostic (2.84e-1)" "unprognostic (1.85e-1)" "unprognostic (2.50e-1)" "unprognostic (3.25e-1)" "unprognostic (1.54e-1)" "unprognostic (1.33e-3)" "unprognostic (1.03e-2)" "unprognostic (1.57e-1)" "unprognostic (6.10e-2)" "potential prognostic unfavorable (1.21e-4)" "unprognostic (8.46e-2)" "unprognostic (1.83e-2)" "unprognostic (1.93e-2)" "unprognostic (1.12e-1)" "unprognostic (1.85e-2)" "unprognostic (3.14e-2)" "unprognostic (9.14e-3)" "unprognostic (3.60e-1)" "unprognostic (3.52e-1)" "unprognostic (4.57e-2)" "unprognostic (1.37e-1)" "unprognostic (1.37e-1)" "unprognostic (3.11e-2)" "unprognostic (4.50e-3)" "unprognostic (8.47e-3)" "unprognostic (2.22e-2)" "unprognostic (7.73e-2)" "unprognostic (1.37e-1)" COL15A1 ENSG00000204291 "Collagen type XV alpha 1 chain" P39059 9 98943179-99070792 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 215.4" "Cell type enhanced" "Detected in many" "Adipocytes: 184.0;Adrenal cortex cells: 335.6;Decidual stromal cells: 309.6;Endometrial stromal cells: 146.7;Fibro-adipogenic progenitors: 927.3;Fibroblasts: 244.0;Leydig cells: 712.1;Peritubular myoid cells: 730.8;Vascular endothelial cells: 286.3" "Cell type enriched" "Detected in many" 17 "fibroblast: 502.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 13.8;skin cancer: 14.8" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Heart muscle - Fibroblasts, Lung - Fibroblasts_2, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Testis - Peritubular cells" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 7 "spinal cord: 56.0" "HPA017913, HPA017915" Enhanced Enhanced "Endoplasmic reticulum" "Secreted to extracellular matrix" "Developmental protein" NA NA 6700000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 36: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "Endoplasmic reticulum" "HPA017913: , HPA017915: " "unprognostic (1.25e-2)" "unprognostic (3.51e-1)" "unprognostic (6.09e-2)" "unprognostic (1.41e-2)" "unprognostic (1.80e-1)" "unprognostic (2.91e-1)" "unprognostic (1.28e-1)" "unprognostic (2.96e-2)" "unprognostic (2.37e-2)" "unprognostic (3.34e-1)" "potential prognostic favorable (7.29e-4)" "unprognostic (1.16e-3)" "potential prognostic unfavorable (1.91e-4)" "potential prognostic favorable (9.95e-4)" "unprognostic (4.75e-3)" "unprognostic (6.05e-2)" "potential prognostic unfavorable (1.63e-4)" "unprognostic (5.40e-2)" "unprognostic (1.87e-2)" "unprognostic (1.75e-1)" "unprognostic (7.37e-2)" "unprognostic (2.06e-1)" "unprognostic (8.02e-2)" "unprognostic (1.22e-1)" "unprognostic (4.91e-2)" "unprognostic (6.42e-2)" "unprognostic (1.49e-2)" "unprognostic (5.31e-3)" "unprognostic (1.01e-1)" "unprognostic (2.46e-2)" "unprognostic (3.87e-1)" COL16A1 ENSG00000084636 "Collagen type XVI alpha 1 chain" Q07092 1 31652263-31704319 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 146.2;Bergmann glia: 84.3;Ependymal cells: 140.5;Fibroblasts: 70.8;Leydig cells: 68.6;Oligodendrocyte progenitor cells: 105.6;Oligodendrocytes: 145.1;Ovarian stromal cells: 82.7;Peritubular myoid cells: 141.4" "Cell type enhanced" "Detected in all" "astrocyte: 180.3;committed oligodendrocyte precursor: 201.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 57.6" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Colon - Enteric glia cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA027235 Approved "Golgi apparatus,Cytosol" "Secreted to extracellular matrix" "Cell adhesion" NA NA 390000 "Cluster 75: Ovary - Mixed function" "Cluster 30: White matter - Myelination" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 94: Gonadal somatic cells - Mixed function" "Golgi apparatus" Cytosol "HPA027235: " "unprognostic (1.07e-2)" "unprognostic (2.68e-2)" "unprognostic (5.06e-2)" "unprognostic (2.01e-2)" "unprognostic (2.09e-2)" "unprognostic (4.53e-3)" "unprognostic (7.17e-3)" "potential prognostic unfavorable (4.59e-4)" "unprognostic (5.52e-2)" "unprognostic (4.49e-2)" "unprognostic (6.16e-2)" "unprognostic (1.03e-1)" "potential prognostic unfavorable (4.48e-6)" "unprognostic (2.25e-2)" "unprognostic (1.96e-1)" "unprognostic (9.56e-2)" "unprognostic (3.54e-1)" "unprognostic (9.64e-3)" "unprognostic (2.05e-1)" "unprognostic (1.13e-3)" "unprognostic (1.11e-1)" "unprognostic (1.93e-1)" "unprognostic (1.89e-1)" "unprognostic (3.43e-1)" "unprognostic (8.14e-2)" "unprognostic (3.38e-3)" "unprognostic (3.28e-2)" "unprognostic (1.04e-1)" "unprognostic (8.23e-2)" "unprognostic (1.34e-2)" "unprognostic (3.02e-1)" COL17A1 "BP180, BPAG2" ENSG00000065618 "Collagen type XVII alpha 1 chain" Q9UMD9 10 104031286-104085880 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "skin 1: 548.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 1195.6;Breast myoepithelial cells: 265.2;Colonocytes: 148.3;Enterocytes: 121.0;Epididymal basal cells: 122.2;Esophageal basal cells: 151.4;Medullary thymic epithelial cells: 199.2;Ocular epithelial cells: 738.2;Salivary basal cells: 163.2;Salivary myoepithelial cells: 144.1;Suprabasal keratinocytes: 154.2" "Cell type enhanced" "Detected in some" "ependymal cell: 1.7;medium spiny neuron: 1.6;midbrain-derived inhibitory: 1.4" "Cancer enriched" "Detected in many" 4 "Head and Neck Squamous Cell Carcinoma (TCGA): 509.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 200.6;head and neck cancer: 440.5" "Breast - Breast myoepithelial cells, Colon - Colon enterocytes, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other), Spleen - Neutrophils_1, Stomach - Gastric mucous cells" "Region enriched" "Detected in single" 4 "cerebellum: 1.0" "Low region specificity" "Detected in all" "HPA043673, HPA052963" Enhanced Supported "Golgi apparatus,Plasma membrane" "Secreted to extracellular matrix" "No annotated function" NA NA 24000 "Cluster 37: Skin - Keratinization" "Cluster 15: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 14 "Plasma membrane" "Golgi apparatus" "HPA043673: , HPA052963: " "unprognostic (1.00e-1)" "potential prognostic favorable (1.86e-5)" "unprognostic (3.71e-1)" "unprognostic (7.85e-2)" "unprognostic (1.75e-1)" "unprognostic (2.60e-1)" "unprognostic (2.52e-1)" "unprognostic (3.46e-1)" "unprognostic (2.25e-1)" "unprognostic (5.44e-2)" "unprognostic (8.05e-2)" "unprognostic (5.98e-2)" "unprognostic (2.48e-3)" "potential prognostic unfavorable (3.96e-7)" "unprognostic (5.57e-3)" "unprognostic (6.09e-2)" "unprognostic (1.51e-1)" "unprognostic (2.41e-2)" "unprognostic (8.04e-2)" "unprognostic (1.13e-1)" "unprognostic (1.47e-1)" "unprognostic (3.41e-2)" "unprognostic (2.28e-1)" COL18A1 "KNO, KNO1, KS" ENSG00000182871 "Collagen type XVIII alpha 1 chain" P39060 21 45405165-45513720 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes, Glaucoma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 483.3;liver: 547.3" "Cell type enhanced" "Detected in many" "Endometrial luminal cells: 345.1;Epididymal basal cells: 274.1;Gonadotrophs: 290.7;Hepatocytes: 637.6;Pancreatic duct cells: 351.7;Pericytes: 406.8;Proximal tubule cells: 296.4;Vascular smooth muscle cells: 435.5" "Cell type enhanced" "Detected in all" "fibroblast: 463.1;vascular associated smooth muscle cell: 371.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 3.2" "Lineage enriched" "Detected in single" 6 "granulocytes: 3.2" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Liver - Hepatocytes, Minor Salivary Gland - Endothelial cells, Prostate - Endothelial cells, Skin - Fibroblasts_1" "Region enriched" "Detected in all" 6 "cerebellum: 22.1" "Low region specificity" "Detected in all" "HPA030933, HPA036104" Supported Approved "Golgi apparatus" "Secreted to extracellular matrix" "Cell adhesion" NA NA 160000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 30: White matter - Myelination" "Cluster 15: Kidney cancer - Membrane components" "Cluster 110: Mural cells - ECM organization" 1 "Golgi apparatus" "HPA030933: , HPA036104: " "unprognostic (3.91e-1)" "unprognostic (1.24e-1)" "unprognostic (1.36e-1)" "unprognostic (4.89e-2)" "unprognostic (2.11e-2)" "unprognostic (1.14e-2)" "unprognostic (1.39e-1)" "unprognostic (8.96e-3)" "unprognostic (1.02e-1)" "unprognostic (1.33e-1)" "unprognostic (1.43e-1)" "unprognostic (2.89e-2)" "unprognostic (4.52e-2)" "validated prognostic favorable (1.25e-4)" "validated prognostic favorable (5.80e-5)" "unprognostic (1.15e-2)" "unprognostic (9.79e-2)" "unprognostic (3.14e-2)" "unprognostic (2.14e-1)" "unprognostic (3.41e-1)" "unprognostic (1.44e-1)" "unprognostic (1.98e-1)" "unprognostic (1.23e-2)" "unprognostic (9.73e-2)" "unprognostic (6.54e-2)" "unprognostic (1.80e-2)" "unprognostic (5.16e-2)" "unprognostic (2.65e-2)" "unprognostic (1.38e-1)" "unprognostic (8.45e-3)" "unprognostic (1.50e-1)" COL19A1 ENSG00000082293 "Collagen type XIX alpha 1 chain" Q14993 6 69866556-70212468 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion, Differentiation, Myogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.8;lymphoid tissue: 3.0;urinary bladder: 2.6" "Cell type enhanced" "Detected in many" "B-cells: 306.7;Lactotrophs: 152.7;Myonuclei: 186.8;Proximal tubule cells: 214.7;Smooth muscle cells: 175.6;Thymic myoid cells: 164.5" "Cell type enhanced" "Detected in all" "hippocampal dentate gyrus: 385.8" "Cancer enhanced" "Detected in single" "Skin Cutaneous Melanoma (TCGA): 1.1" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 218 "memory B-cell: 14.6;naive B-cell: 32.0" "Lineage enriched" "Detected in single" 299 "B-cells: 32.0" "Cancer enhanced" "Detected in some" "Sarcoma: 3.9;skin cancer: 10.4" "Kidney - Proximal tubular cells, Pituitary gland - Lactotropes, Spleen - B-cells (Spleen), Stomach - Fibroblasts" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA042422 Uncertain "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 35: Non-specific - DNA binding" "Cluster 69: Skin cancer - ECM organization" "Cluster 46: Skeletal myocytes - Muscle structure & formation" "HPA042422: " "unprognostic (2.76e-1)" "unprognostic (1.91e-1)" "unprognostic (7.83e-2)" COL1A1 OI4 ENSG00000108821 "Collagen type I alpha 1 chain" P02452 17 50184101-50201632 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Dwarfism, Ehlers-Danlos syndrome, FDA approved drug targets, Osteogenesis imperfecta, Osteoporosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 1248.6;gallbladder: 1134.3;ovary: 1143.7" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 637.4;Endometrial stromal cells: 1897.4;Fibroblasts: 1258.4;Hepatic stellate cells: 6616.2;Leydig cells: 590.8;Ovarian stromal cells: 434.5" "Group enriched" "Detected in some" 6 "fibroblast: 118.6;vascular associated smooth muscle cell: 32.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Brain cancer: 1387.0" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblasts_2, Pituitary gland - Corticotropes, Skeletal muscle - Fibroblasts, Skin - Fibroblasts_1, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 170.5" "HPA011795, HPA012111" Approved Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" "No annotated function" NA NA 150000000 "Cluster 75: Ovary - Mixed function" "Cluster 12: Non-specific - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 44 "Endoplasmic reticulum" Vesicles "HPA011795: , HPA012111: " "unprognostic (1.71e-2)" "unprognostic (3.02e-1)" "unprognostic (9.50e-2)" "unprognostic (5.85e-3)" "unprognostic (2.11e-2)" "unprognostic (2.74e-1)" "unprognostic (6.08e-2)" "unprognostic (9.19e-3)" "unprognostic (1.40e-1)" "unprognostic (1.38e-2)" "unprognostic (1.98e-3)" "unprognostic (1.00e-1)" "potential prognostic unfavorable (8.35e-7)" "unprognostic (4.68e-2)" "unprognostic (1.75e-1)" "potential prognostic unfavorable (9.95e-4)" "unprognostic (3.45e-2)" "unprognostic (6.12e-2)" "unprognostic (3.04e-1)" "unprognostic (4.06e-3)" "unprognostic (3.29e-2)" "unprognostic (4.66e-2)" "unprognostic (9.19e-2)" "unprognostic (9.67e-2)" "unprognostic (4.08e-2)" "unprognostic (7.63e-3)" "unprognostic (3.39e-2)" "unprognostic (9.07e-3)" "unprognostic (6.56e-2)" "unprognostic (5.02e-2)" "unprognostic (2.00e-1)" COL1A2 OI4 ENSG00000164692 "Collagen type I alpha 2 chain" P08123 7 94394895-94431227 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Dwarfism, Ehlers-Danlos syndrome, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 1633.0;ovary: 1332.9;smooth muscle: 1268.5" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 516.5;Endometrial glandular cells: 695.4;Endometrial luminal cells: 476.4;Endometrial stromal cells: 740.5;Fibro-adipogenic progenitors: 677.4;Fibroblasts: 1710.9;Hepatic stellate cells: 4421.5;Leydig cells: 1449.5;Ovarian stromal cells: 512.1;Pericytes: 579.3;Peritubular myoid cells: 728.6;Pituicytes/FSCs: 546.0;Sertoli cells: 780.7" "Cell type enhanced" "Detected in some" "fibroblast: 815.9;pericyte: 374.1;vascular associated smooth muscle cell: 173.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 1425.0;Sarcoma: 742.4" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Adrenal gland - Fibroblasts, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblasts_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblasts_1, Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 172.6" "CAB032650, HPA068464, HPA068494" Approved Supported "Endoplasmic reticulum" "Secreted to extracellular matrix" "No annotated function" NA NA 28000000 "Cluster 75: Ovary - Mixed function" "Cluster 12: Non-specific - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 21 "Endoplasmic reticulum" "CAB032650: , HPA068464: , HPA068494: " "unprognostic (2.60e-2)" "unprognostic (2.12e-1)" "unprognostic (3.98e-2)" "unprognostic (1.63e-2)" "unprognostic (4.88e-2)" "unprognostic (2.28e-1)" "unprognostic (3.13e-2)" "unprognostic (1.38e-3)" "unprognostic (2.17e-1)" "unprognostic (2.56e-2)" "unprognostic (1.30e-1)" "unprognostic (1.33e-2)" "potential prognostic unfavorable (2.01e-6)" "unprognostic (4.02e-2)" "unprognostic (2.19e-1)" "unprognostic (1.92e-2)" "unprognostic (2.40e-2)" "unprognostic (3.46e-2)" "unprognostic (4.41e-1)" "unprognostic (4.59e-3)" "unprognostic (1.99e-2)" "unprognostic (3.98e-2)" "unprognostic (4.56e-1)" "unprognostic (1.98e-1)" "unprognostic (7.42e-2)" "unprognostic (2.99e-3)" "unprognostic (2.91e-2)" "unprognostic (9.55e-3)" "unprognostic (7.60e-2)" "unprognostic (6.55e-2)" "unprognostic (3.18e-1)" COL20A1 KIAA1510 ENSG00000101203 "Collagen type XX alpha 1 chain" Q9P218 20 63293186-63334851 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 7.2;testis: 2.3" "Group enriched" "Detected in some" 4 "Oligodendrocyte progenitor cells: 107.0;Retinal pigment epithelial cells: 93.8" "Group enriched" "Detected in many" 32 "committed oligodendrocyte precursor: 41.5;oligodendrocyte precursor cell: 113.8" "Cancer enriched" "Detected in some" 21 "Glioblastoma Multiforme (TCGA): 38.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Bile duct cancer: 1.4" "Low region specificity" "Detected in many" HPA060109 Approved "Golgi apparatus,Vesicles" "Secreted to extracellular matrix" "No annotated function" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 1 "Golgi apparatus, Vesicles" "HPA060109: " "unprognostic (3.97e-1)" "unprognostic (1.49e-2)" "unprognostic (1.03e-1)" COL21A1 ENSG00000124749 "Collagen type XXI alpha 1 chain" Q96P44 6 56056590-56394094 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 28.5;placenta: 26.6" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 295.3;Cytotrophoblasts: 147.1;Ependymal cells: 320.9;Extravillous trophoblasts: 331.4;Pituitary stem cells: 493.3;Respiratory ciliated cells: 291.9;Salivary acinar cells: 172.0;Salivary ionocytes: 605.8;Schwann cells: 172.4;Thymic myoid cells: 247.5" "Cell type enhanced" "Detected in all" "ependymal cell: 411.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 9.0;prostate cancer: 9.2;Rhabdoid: 8.7;testis cancer: 10.3" "Heart muscle - Cardiomyocytes, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Smooth muscle cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" HPA031212 Supported Cytosol "Secreted to extracellular matrix" "No annotated function" NA NA 220000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 44: Non-specific - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 46: Skeletal myocytes - Muscle structure & formation" Cytosol "HPA031212: " "unprognostic (4.57e-2)" "unprognostic (7.80e-2)" "unprognostic (3.41e-2)" "unprognostic (1.25e-1)" "unprognostic (3.17e-2)" "unprognostic (2.32e-2)" "unprognostic (5.91e-3)" "unprognostic (3.27e-1)" "validated prognostic favorable (3.32e-6)" "validated prognostic favorable (7.41e-6)" "unprognostic (2.43e-2)" "unprognostic (1.51e-2)" "unprognostic (5.94e-2)" "unprognostic (8.16e-2)" "unprognostic (7.68e-2)" "unprognostic (1.61e-1)" "unprognostic (8.59e-2)" "unprognostic (1.83e-1)" "unprognostic (7.49e-2)" "unprognostic (2.33e-1)" "unprognostic (6.24e-2)" "unprognostic (9.06e-2)" COL22A1 ENSG00000169436 "Collagen type XXII alpha 1 chain" Q8NFW1 8 138588235-138914041 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "pituitary gland: 40.4" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 74.5;Bergmann glia: 230.1;Early spermatids: 66.2;Epididymal basal cells: 50.1;Gonadotrophs: 411.7;Lactotrophs: 101.0;Late spermatids: 52.3;Müller glia: 93.2;Oocytes: 96.7;Pituitary stem cells: 73.2;Somatotrophs: 49.4;Thyrotrophs: 203.5" "Cell type enriched" "Detected in many" 4 "Bergmann glia: 226.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal medulla cells, Breast - T-cells, Colon - Enteric glia cells, Minor Salivary Gland - Minor salivary glandular cells, Stomach - Gastric enteroendocrine cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" HPA024830 Enhanced Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" "No annotated function" NA NA "Cluster 20: Pituitary gland - Hormone signaling" "Cluster 43: Hindbrain - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" Vesicles "Endoplasmic reticulum" "HPA024830: " "unprognostic (1.43e-1)" "unprognostic (2.47e-1)" "unprognostic (5.25e-1)" "unprognostic (3.24e-1)" "unprognostic (3.42e-3)" "unprognostic (6.03e-2)" "unprognostic (4.30e-2)" "validated prognostic unfavorable (1.75e-10)" "validated prognostic unfavorable (9.75e-4)" "potential prognostic unfavorable (1.04e-4)" "unprognostic (3.91e-2)" "unprognostic (2.63e-1)" "potential prognostic unfavorable (5.33e-5)" "unprognostic (6.98e-2)" "unprognostic (3.46e-3)" "unprognostic (2.10e-1)" "unprognostic (1.67e-1)" "unprognostic (7.27e-2)" "unprognostic (1.10e-1)" "potential prognostic unfavorable (7.44e-4)" "unprognostic (4.03e-2)" "unprognostic (1.97e-1)" "unprognostic (9.21e-2)" "unprognostic (1.24e-1)" "unprognostic (8.00e-2)" "potential prognostic unfavorable (3.01e-6)" COL23A1 DKFZp434K0621 ENSG00000050767 "Collagen type XXIII alpha 1 chain" Q86Y22 5 178237476-178590393 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "thyroid gland: 18.8" "Cell type enhanced" "Detected in many" "Bergmann glia: 310.2;Cardiomyocytes: 153.3;Epididymal basal cells: 117.3;Erythrocyte progenitors: 141.8;Müller glia: 420.9;Neutrophil progenitors: 127.7;Salivary myoepithelial cells: 102.7;Thymic myoid cells: 137.3;Undifferentiated spermatogonia: 110.7" "Cell type enhanced" "Detected in all" "Bergmann glia: 282.8" "Cancer enhanced" "Detected in some" "Kidney Renal Clear Cell Carcinoma (TCGA): 20.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 5.2;Leukemia: 9.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067824 Uncertain NA NA "Cluster 33: Thyroid gland - Tissue development" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 1 "HPA067824: " "unprognostic (8.12e-2)" "unprognostic (3.77e-2)" "potential prognostic favorable (3.74e-4)" "unprognostic (4.31e-3)" "unprognostic (2.46e-2)" "unprognostic (9.37e-3)" "unprognostic (4.38e-2)" "unprognostic (9.33e-2)" "unprognostic (4.46e-3)" "unprognostic (8.64e-3)" COL24A1 ENSG00000171502 "Collagen type XXIV alpha 1 chain" Q17RW2 1 85729233-86156943 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 6.6;intestine: 6.2" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 159.3;Hematopoietic stem cells: 328.5;Innate lymphoid cells: 134.5;Melanocytes: 152.6;Monocyte progenitors: 97.3;Müller glia: 220.6;pDCs: 423.9;Platelets: 127.5;Renal collecting duct intercalated cells: 108.4;Thymocytes: 343.0" "Cell type enhanced" "Detected in all" "hippocampal CA1-3: 818.7;miscellaneous: 458.1" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 9 "plasmacytoid DC: 2.7" "Lineage enriched" "Detected in single" 9 "dendritic cells: 2.7" "Cancer enhanced" "Detected in some" "Leukemia: 2.6;Myeloma: 4.1" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" "No annotated function" NA NA 15000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 35: Neurons - Synaptic function & neurogenesis" 1 "unprognostic (1.20e-1)" "unprognostic (5.32e-1)" "unprognostic (7.60e-3)" "unprognostic (3.29e-2)" "unprognostic (4.41e-1)" "unprognostic (3.88e-1)" "unprognostic (1.47e-1)" "unprognostic (2.09e-1)" "unprognostic (1.77e-1)" COL25A1 ENSG00000188517 "Collagen type XXV alpha 1 chain" Q9BXS0 4 108808725-109302752 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Heparin-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 20.3;testis: 16.7" "Cell type enriched" "Detected in many" 10 "Pituicytes/FSCs: 9594.6" "Cell type enhanced" "Detected in all" "hippocampal dentate gyrus: 930.6;mammillary body: 849.5;medium spiny neuron: 694.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 4.7" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA029107 Approved "Endoplasmic reticulum,Vesicles,Cytosol" NA NA "Cluster 47: Testis - Mixed function" "Cluster 29: Forebrain - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 1 "Vesicles, Cytosol" "Endoplasmic reticulum" "HPA029107: " "unprognostic (4.11e-2)" "unprognostic (7.12e-2)" "unprognostic (2.94e-1)" "validated prognostic favorable (3.33e-6)" "validated prognostic favorable (2.70e-5)" "unprognostic (1.83e-1)" "unprognostic (2.59e-2)" "unprognostic (7.46e-3)" "unprognostic (2.36e-2)" COL26A1 "EMI6, EMID2, Emu2" ENSG00000160963 "Collagen type XXVI alpha 1 chain" Q96A83 7 101362875-101559024 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 21.8;kidney: 7.4" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 64.3;Brain inhibitory neurons: 31.0;Choroid plexus epithelial cells: 35.9;Differentiating spermatogonia: 50.1;Loop of henle epithelial cells: 108.8;pDCs: 197.5;Renal collecting duct principal cells: 35.1" "Cell type enhanced" "Detected in all" "upper-layer intratelencephalic: 206.7" "Group enriched" "Detected in many" 5 "Ovary Serous Cystadenocarcinoma (TCGA): 8.5;Prostate Adenocarcinoma (TCGA): 6.5;Testicular Germ Cell Tumor (TCGA): 25.1;Uterine Corpus Endometrial Carcinoma (TCGA): 24.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 44 "plasmacytoid DC: 9.2" "Lineage enriched" "Detected in single" 44 "dendritic cells: 9.2" "Cancer enhanced" "Detected in many" "ovarian cancer: 24.1;Rhabdoid: 54.3;Uterine cancer: 24.1" "Liver - Hepatocytes, Pituitary gland - Gonadotropes, Prostate - Prostate glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA027059 Approved Approved Vesicles "Secreted to extracellular matrix" "No annotated function" NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" Vesicles "HPA027059: " "unprognostic (1.44e-2)" "unprognostic (2.12e-1)" "unprognostic (3.17e-2)" "unprognostic (2.12e-2)" "potential prognostic favorable (4.46e-6)" "unprognostic (1.48e-1)" "unprognostic (7.13e-3)" "unprognostic (4.13e-2)" "unprognostic (1.24e-1)" "unprognostic (5.80e-2)" "unprognostic (1.65e-1)" "unprognostic (1.90e-1)" COL27A1 "FLJ11895, KIAA1870, MGC11337" ENSG00000196739 "Collagen type XXVII alpha 1 chain" Q8IZC6 9 114155537-114312511 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 98.1;cervix: 113.0" "Cell type enhanced" "Detected in many" "Cholangiocytes: 127.9;Extravillous trophoblasts: 251.6;Proximal tubule cells: 274.9;Tuft cells: 449.6" "Group enriched" "Detected in many" 4 "astrocyte: 121.5;Bergmann glia: 46.1;ependymal cell: 72.5;fibroblast: 101.2;oligodendrocyte precursor cell: 78.0;pericyte: 73.0;upper rhombic lip: 172.2;vascular associated smooth muscle cell: 95.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in some" "Region enriched" "Detected in all" 20 "cerebellum: 102.1" "HPA021884, HPA048471" Uncertain "Secreted to extracellular matrix" "No annotated function" NA NA "Cluster 64: Non-specific - Transcription" "Cluster 2: Neurons - Nucleosome" "Cluster 24: Non-specific - Unknown function" "Cluster 95: Tuft cells - Chemosensory signaling" 1 "HPA021884: , HPA048471: " "unprognostic (2.32e-1)" "unprognostic (1.27e-1)" "unprognostic (1.44e-2)" "unprognostic (3.01e-1)" "unprognostic (2.11e-1)" "unprognostic (1.98e-1)" "unprognostic (2.17e-2)" "unprognostic (1.18e-1)" "unprognostic (1.88e-1)" "unprognostic (1.49e-1)" "unprognostic (3.18e-1)" "unprognostic (1.72e-2)" "unprognostic (1.11e-2)" "unprognostic (1.06e-1)" "unprognostic (3.23e-2)" "unprognostic (1.08e-1)" "unprognostic (2.67e-2)" "unprognostic (3.46e-1)" "unprognostic (1.72e-1)" "unprognostic (3.01e-1)" "unprognostic (3.99e-2)" "unprognostic (1.23e-3)" "unprognostic (3.12e-1)" "unprognostic (1.80e-1)" "unprognostic (3.12e-2)" "unprognostic (2.80e-1)" "unprognostic (2.72e-1)" "unprognostic (2.66e-1)" "unprognostic (2.98e-1)" "unprognostic (7.85e-3)" "unprognostic (3.35e-1)" COL28A1 ENSG00000215018 "Collagen type XXVIII alpha 1 chain" Q2UY09 7 7356203-7535873 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 17.3" "Cell type enhanced" "Detected in many" "Corticotrophs: 378.5;Endometrial ciliated cells: 139.1;Ependymal cells: 247.1;Lacrimal acinar cells: 231.9;Respiratory ciliated cells: 208.2;Salivary acinar cells: 132.9;Schwann cells: 444.0;Thymic myoid cells: 284.2" "Cell type enhanced" "Detected in all" "ependymal cell: 241.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 10.2" "Adipose subcutaneous - Smooth muscle cells, Breast - Breast glandular cells, Colon - Enteric glia cells, Lung - Respiratory ciliated cells, Pituitary gland - Corticotropes, Thyroid gland - Fibroblasts" "Region enriched" "Detected in single" 8 "olfactory bulb: 3.6" "Region enriched" "Detected in some" 31 "spinal cord: 44.1" "HPA043844, HPA060468" Uncertain Approved Nucleoplasm,Cytosol "Secreted to extracellular matrix" "Cell adhesion" NA NA "Cluster 38: Non-specific - Basic cellular processes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 40: Non-specific - Unknown function" "Cluster 61: Schwann cells & Melanocytes - Mixed function" Cytosol Nucleoplasm "HPA043844: , HPA060468: " "unprognostic (1.09e-1)" "unprognostic (5.83e-2)" "unprognostic (2.23e-2)" "unprognostic (1.19e-2)" "unprognostic (4.32e-2)" "unprognostic (4.43e-2)" "unprognostic (5.85e-2)" "unprognostic (8.39e-2)" "unprognostic (3.48e-2)" "unprognostic (1.27e-3)" "potential prognostic unfavorable (3.53e-4)" "unprognostic (6.61e-2)" "unprognostic (2.14e-1)" "unprognostic (8.58e-3)" "unprognostic (7.06e-3)" "unprognostic (7.57e-2)" "unprognostic (1.34e-1)" "unprognostic (9.43e-3)" "unprognostic (1.04e-1)" "unprognostic (1.61e-1)" "unprognostic (6.01e-3)" "unprognostic (1.61e-2)" "unprognostic (3.05e-2)" "unprognostic (1.31e-1)" "unprognostic (1.62e-1)" "unprognostic (2.85e-2)" "unprognostic (6.16e-2)" "unprognostic (3.99e-1)" COL2A1 "AOM, SEDC, STL1" ENSG00000139219 "Collagen type II alpha 1 chain" P02458 12 47972967-48004554 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted secreted proteins" "Cancer-related genes, Cataract, Deafness, Disease variant, Dwarfism, FDA approved drug targets, Stickler syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "epididymis: 18.0;pituitary gland: 8.8;retina: 5.2;stomach 1: 11.6" "Cell type enhanced" "Detected in some" "Early spermatids: 15.4;Epididymal principal cells: 58.3;Gonadotrophs: 41.0;Granulosa cells: 19.5;Müller glia: 26.2;Neuroendocrine cells: 42.7;Parietal cells: 127.3;Pituitary stem cells: 18.6;Retinal amacrine cells: 41.6;Tuft cells: 34.6" "Cell type enhanced" "Detected in some" "fibroblast: 2.8;hippocampal dentate gyrus: 5.7" "Group enriched" "Detected in many" 4 "Breast Invasive Carcinoma (TCGA): 22.3;Prostate Adenocarcinoma (TCGA): 19.7;Skin Cutaneous Melanoma (TCGA): 14.8;Testicular Germ Cell Tumor (TCGA): 22.7;Uterine Corpus Endometrial Carcinoma (TCGA): 8.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 7 "liver cancer: 78.5" "Pituitary gland - Gonadotropes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB002214, HPA055753" Approved Approved Nucleoplasm "Secreted to extracellular matrix" "No annotated function" No NA 13000000 "Cluster 22: Epididymis - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 3 Nucleoplasm "CAB002214: , HPA055753: " "unprognostic (6.77e-3)" "unprognostic (2.16e-1)" "unprognostic (5.49e-2)" "unprognostic (7.27e-2)" "unprognostic (2.63e-2)" "unprognostic (1.11e-1)" "unprognostic (5.52e-2)" "unprognostic (7.13e-2)" "unprognostic (1.04e-1)" "unprognostic (6.95e-2)" "unprognostic (7.34e-2)" "unprognostic (1.23e-1)" "unprognostic (1.07e-1)" "unprognostic (1.93e-1)" "unprognostic (2.54e-2)" "unprognostic (1.91e-1)" "unprognostic (5.96e-2)" "unprognostic (1.81e-1)" "unprognostic (1.31e-1)" COL3A1 EDS4A ENSG00000168542 "Collagen type III alpha 1 chain" P02461 2 188974373-189012746 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Aortic aneurysm, Disease variant, Ehlers-Danlos syndrome, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 2222.3;gallbladder: 1957.3;placenta: 1861.3;smooth muscle: 1998.4" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 783.1;Endometrial stromal cells: 2716.9;Fibro-adipogenic progenitors: 479.9;Fibroblasts: 1545.0;Hepatic stellate cells: 3789.0;Leydig cells: 422.3;Pericytes: 574.7" "Cell type enhanced" "Detected in some" "fibroblast: 216.1;vascular associated smooth muscle cell: 78.5" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in all" 5 "cerebral cortex: 21.6;choroid plexus: 22.8;thalamus: 22.8;white matter: 8.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 1300.8;Sarcoma: 607.6;testis cancer: 879.7" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Minor Salivary Gland - Fibroblasts, Pituitary gland - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblasts_1, Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 74.6" "HPA007583, CAB016766, CAB059993" Approved Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" "No annotated function" NA NA 30000000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 12: Non-specific - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 1 "Endoplasmic reticulum" "CAB016766: , CAB059993: , HPA007583: " "unprognostic (5.65e-3)" "unprognostic (2.00e-1)" "unprognostic (9.08e-2)" "unprognostic (1.18e-2)" "unprognostic (9.14e-2)" "unprognostic (1.92e-1)" "unprognostic (2.77e-1)" "unprognostic (3.32e-3)" "unprognostic (1.37e-1)" "unprognostic (3.85e-3)" "unprognostic (2.37e-1)" "unprognostic (4.75e-3)" "potential prognostic unfavorable (1.93e-8)" "unprognostic (5.86e-2)" "unprognostic (2.07e-1)" "unprognostic (5.82e-2)" "unprognostic (8.53e-3)" "unprognostic (4.80e-2)" "unprognostic (2.62e-1)" "unprognostic (3.43e-3)" "potential prognostic unfavorable (8.45e-4)" "unprognostic (3.54e-2)" "unprognostic (4.40e-1)" "unprognostic (2.24e-1)" "unprognostic (8.48e-2)" "unprognostic (4.48e-3)" "unprognostic (3.44e-3)" "unprognostic (1.33e-3)" "unprognostic (4.31e-2)" "unprognostic (7.46e-2)" "unprognostic (4.51e-2)" COL4A1 ENSG00000187498 "Collagen type IV alpha 1 chain" P02462 13 110148963-110307157 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 846.2" "Cell type enhanced" "Detected in many" "Adipocytes: 939.8;Alveolar cells type 1: 394.8;Decidual stromal cells: 410.4;Endometrial stromal cells: 480.8;Extravillous trophoblasts: 1310.1;Fibro-adipogenic progenitors: 335.6;Fibroblasts: 573.8;Hepatic stellate cells: 987.6;Pericytes: 1138.1;Smooth muscle cells: 428.2;Vascular endothelial cells: 491.1;Vascular smooth muscle cells: 638.3" "Cell type enriched" "Detected in many" 5 "vascular associated smooth muscle cell: 770.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 215.6" "Breast - Adipocytes (Breast), Pituitary gland - Endothelial cells, Prostate - Smooth muscle cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB001695 Approved "Secreted to extracellular matrix" "Developmental protein" NA NA 320000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 29: Forebrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 110: Mural cells - ECM organization" 3 "CAB001695: " "unprognostic (1.74e-1)" "unprognostic (9.11e-2)" "unprognostic (1.68e-1)" "unprognostic (6.66e-3)" "unprognostic (6.94e-2)" "unprognostic (1.66e-1)" "unprognostic (1.69e-1)" "unprognostic (2.30e-1)" "unprognostic (2.98e-1)" "unprognostic (1.37e-1)" "validated prognostic favorable (1.72e-5)" "validated prognostic favorable (5.69e-4)" "potential prognostic unfavorable (3.02e-6)" "unprognostic (1.73e-2)" "unprognostic (2.50e-1)" "unprognostic (3.27e-2)" "potential prognostic unfavorable (4.13e-5)" "unprognostic (5.47e-2)" "unprognostic (2.61e-1)" "unprognostic (9.54e-2)" "unprognostic (5.01e-2)" "unprognostic (5.26e-2)" "unprognostic (1.75e-1)" "unprognostic (2.49e-1)" "unprognostic (5.14e-2)" "unprognostic (9.24e-2)" "unprognostic (3.92e-2)" "unprognostic (3.34e-2)" "unprognostic (9.75e-2)" "unprognostic (2.78e-2)" "unprognostic (9.08e-2)" COL4A2 "DKFZp686I14213, FLJ22259" ENSG00000134871 "Collagen type IV alpha 2 chain" P08572 13 110305812-110513209 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 445.7" "Cell type enhanced" "Detected in many" "Adipocytes: 1512.1;Alveolar cells type 1: 723.0;Decidual stromal cells: 494.3;Endometrial stromal cells: 523.0;Extravillous trophoblasts: 1147.6;Fibro-adipogenic progenitors: 437.2;Fibroblasts: 550.6;Hepatic stellate cells: 1220.0;Pericytes: 1082.0;Salivary myoepithelial cells: 575.7;Smooth muscle cells: 733.6;Vascular endothelial cells: 481.3;Vascular smooth muscle cells: 832.9" "Cell type enhanced" "Detected in many" "vascular associated smooth muscle cell: 671.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 278.9" "Breast - Adipocytes (Breast), Pituitary gland - Endothelial cells, Prostate - Smooth muscle cells, Skeletal muscle - Endothelial cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010751, HPA029118, HPA069337" Enhanced Approved Vesicles "Secreted to extracellular matrix" "Developmental protein" NA NA 2400000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 29: Forebrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 110: Mural cells - ECM organization" 2 Vesicles "CAB010751: , HPA029118: , HPA069337: " "unprognostic (1.80e-1)" "unprognostic (3.51e-1)" "unprognostic (4.32e-1)" "unprognostic (1.72e-2)" "unprognostic (4.51e-2)" "unprognostic (7.19e-2)" "unprognostic (1.90e-1)" "unprognostic (2.26e-1)" "unprognostic (4.20e-2)" "unprognostic (4.15e-2)" "potential prognostic favorable (7.69e-6)" "unprognostic (1.16e-3)" "unprognostic (5.45e-2)" "unprognostic (2.82e-2)" "unprognostic (3.94e-1)" "unprognostic (7.08e-2)" "unprognostic (1.99e-3)" "unprognostic (3.85e-2)" "unprognostic (2.29e-1)" "unprognostic (2.35e-2)" "unprognostic (4.83e-1)" "unprognostic (1.12e-1)" "unprognostic (2.83e-1)" "unprognostic (2.46e-1)" "unprognostic (3.24e-1)" "unprognostic (1.85e-1)" "unprognostic (2.66e-2)" "unprognostic (2.22e-2)" "unprognostic (9.04e-2)" "unprognostic (1.14e-2)" "unprognostic (9.51e-2)" COL4A3 ENSG00000169031 "Collagen type IV alpha 3 chain" Q01955 2 227164624-227314792 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Alport syndrome, Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 33.6" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 380.4;Alveolar cells type 1: 393.5;Choroid plexus epithelial cells: 434.5;Cone photoreceptor cells: 1074.4;Distal convoluted tubule cells: 849.7;Loop of henle epithelial cells: 596.3;Müller glia: 948.8;Myonuclei: 560.0;Podocytes: 2819.5;Retinal pigment epithelial cells: 592.6;Somatotrophs: 445.9;Thyrotrophs: 842.2" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 475.0;pericyte: 641.2" "Group enriched" "Detected in some" 7 "Kidney Chromophobe (TCGA): 7.9;Kidney Renal Clear Cell Carcinoma (TCGA): 4.1;Kidney Renal Papillary Cell Carcinoma (TCGA): 7.2;Lung Adenocarcinoma (TCGA): 5.0;Thyroid Carcinoma (TCGA): 9.3" "Region enhanced" "Detected in all" "choroid plexus: 45.6" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.0" "Lineage enriched" "Detected in single" 7 "B-cells: 1.0" "Cancer enhanced" "Detected in some" "Myeloma: 7.4" "Adrenal gland - Adrenal cortex cells, Lung - Alveolar cells type 1, Spleen - B-cells (Spleen)" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA042064 Approved Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" "Cell adhesion" NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 57: Podocytes - Glomerular filtration" 1 Vesicles "Endoplasmic reticulum" "HPA042064: " "unprognostic (5.78e-2)" "unprognostic (4.67e-1)" "unprognostic (2.03e-2)" "potential prognostic favorable (6.31e-6)" "unprognostic (2.93e-3)" "unprognostic (1.68e-1)" "potential prognostic favorable (4.43e-4)" "potential prognostic favorable (6.59e-4)" "unprognostic (1.58e-1)" "unprognostic (3.74e-2)" "unprognostic (5.16e-3)" "unprognostic (1.57e-3)" "unprognostic (1.87e-2)" COL4A4 CA44 ENSG00000081052 "Collagen type IV alpha 4 chain" P53420 2 227002714-227164453 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Alport syndrome, Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 476.6;Distal convoluted tubule cells: 414.9;Loop of henle epithelial cells: 362.4;Müller glia: 493.8;Myonuclei: 249.6;Papillary tip epithelial cells: 228.0;Podocytes: 1080.7;Renal collecting duct intercalated cells: 272.2;Renal collecting duct principal cells: 332.6;Somatotrophs: 526.0;Thyrotrophs: 848.1" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 194.3;pericyte: 416.8" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 11.8" "Region enhanced" "Detected in all" "choroid plexus: 31.8" "Immune cell enhanced" "Detected in single" "memory B-cell: 2.7" "Lineage enriched" "Detected in single" 5 "B-cells: 2.7" "Cancer enhanced" "Detected in many" "Myeloma: 9.1" "Adrenal gland - Fibroblasts, Lung - Alveolar cells type 1, Spleen - B-cells (Spleen)" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to extracellular matrix" "No annotated function" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 72: Kidney - Transmembrane transport" "Cluster 38: Sub-cortical - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 57: Podocytes - Glomerular filtration" 1 "unprognostic (1.95e-2)" "unprognostic (9.39e-2)" "unprognostic (4.12e-2)" "unprognostic (2.82e-1)" "unprognostic (4.80e-2)" "validated prognostic favorable (4.01e-10)" "validated prognostic favorable (5.20e-4)" "unprognostic (2.40e-2)" "potential prognostic favorable (2.61e-4)" "unprognostic (1.67e-2)" "unprognostic (2.54e-1)" "unprognostic (3.19e-2)" "unprognostic (7.90e-2)" "unprognostic (2.29e-1)" "potential prognostic unfavorable (1.49e-4)" "unprognostic (7.94e-2)" "unprognostic (1.95e-2)" "unprognostic (2.49e-2)" "unprognostic (2.67e-1)" COL4A5 "ASLN, ATS" ENSG00000188153 "Collagen type IV alpha 5 chain" P29400 X 108439838-108697545 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Alport syndrome, Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 621.4;Distal convoluted tubule cells: 341.9;Ependymal cells: 316.9;Epididymal basal cells: 313.6;Oligodendrocytes: 599.7;Pituicytes/FSCs: 815.8;Pituitary stem cells: 765.0;Podocytes: 413.0;Prostatic hillock cells: 539.8;Respiratory basal cells: 535.7" "Cell type enhanced" "Detected in many" "ependymal cell: 351.9;fibroblast: 340.6;oligodendrocyte: 863.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "testis cancer: 60.5" "Adipose subcutaneous - Smooth muscle cells, Pituitary gland - Undifferentiated cells (Pituitary gland)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077177 Approved "Vesicles,Plasma membrane" "Secreted to extracellular matrix" "No annotated function" NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" "Plasma membrane" Vesicles "HPA077177: " "unprognostic (3.39e-3)" "unprognostic (2.49e-2)" "unprognostic (6.64e-2)" "unprognostic (4.76e-2)" "unprognostic (2.92e-2)" "unprognostic (6.50e-2)" "unprognostic (4.97e-2)" "unprognostic (2.32e-1)" "unprognostic (2.11e-1)" "unprognostic (2.57e-1)" "unprognostic (1.16e-2)" "unprognostic (1.12e-1)" "unprognostic (2.00e-2)" "unprognostic (1.09e-2)" "unprognostic (2.68e-2)" "unprognostic (2.14e-2)" "unprognostic (4.11e-3)" "unprognostic (7.54e-2)" "unprognostic (1.39e-2)" "unprognostic (4.03e-1)" "unprognostic (6.78e-2)" "unprognostic (2.65e-1)" "unprognostic (4.91e-2)" "unprognostic (3.43e-2)" "unprognostic (2.62e-1)" "unprognostic (2.08e-1)" "unprognostic (1.74e-1)" "unprognostic (6.48e-3)" "unprognostic (1.90e-1)" "unprognostic (3.66e-2)" "unprognostic (2.92e-1)" COL4A6 ENSG00000197565 "Collagen type IV alpha 6 chain" Q14031 X 108155607-108439497 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Cell adhesion" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 33.0;urinary bladder: 40.3" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 278.1;Distal convoluted tubule cells: 112.9;Ependymal cells: 162.5;Epididymal basal cells: 143.1;Medullary thymic epithelial cells: 115.2;Pituicytes/FSCs: 264.4;Pituitary stem cells: 456.9;Prostatic hillock cells: 131.1;Renal collecting duct principal cells: 91.0;Renal connecting tubule cells: 107.3;Respiratory basal cells: 159.4;Smooth muscle cells: 143.3;Urothelial cells: 98.1" "Cell type enhanced" "Detected in many" "ependymal cell: 172.9;fibroblast: 84.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 16.8" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Breast - Breast myoepithelial cells, Heart muscle - Cardiomyocytes, Kidney - Ascending Loop of Henle cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Spleen - Fibroblasts_2, Stomach - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA065393 Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" "Cell adhesion" NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 1 "Endoplasmic reticulum" "HPA065393: " "unprognostic (5.46e-3)" "unprognostic (3.16e-2)" "unprognostic (1.27e-1)" "unprognostic (4.60e-3)" "unprognostic (2.42e-2)" "unprognostic (2.68e-2)" "unprognostic (2.42e-2)" "unprognostic (1.22e-1)" "unprognostic (1.34e-2)" "unprognostic (7.20e-2)" "unprognostic (9.57e-3)" "unprognostic (6.91e-2)" "unprognostic (2.50e-2)" "unprognostic (2.04e-1)" COL5A1 ENSG00000130635 "Collagen type V alpha 1 chain" P20908 9 134641803-134844843 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" Heparin-binding "Cancer-related genes, Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 144.7" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 175.9;Endometrial stromal cells: 229.0;Ependymal cells: 89.4;Epididymal efferent duct ciliated cells: 85.2;Fibro-adipogenic progenitors: 217.0;Fibroblasts: 202.6;Hepatic stellate cells: 542.2;Leydig cells: 166.4;Myosatellite cells: 174.3;Peritubular myoid cells: 99.2" "Cell type enhanced" "Detected in many" "ependymal cell: 93.3;fibroblast: 90.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 229.7" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblasts_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblasts_1, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA030769 Approved Approved Vesicles "Secreted to extracellular matrix" Other No No 12000000 "Cluster 75: Ovary - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 8 Vesicles "HPA030769: " "unprognostic (3.27e-2)" "unprognostic (2.04e-1)" "unprognostic (2.29e-1)" "unprognostic (5.10e-3)" "unprognostic (2.91e-2)" "unprognostic (2.38e-1)" "unprognostic (1.22e-2)" "unprognostic (7.55e-3)" "unprognostic (7.57e-2)" "unprognostic (3.30e-3)" "unprognostic (1.03e-3)" "unprognostic (2.42e-2)" "potential prognostic unfavorable (1.08e-6)" "unprognostic (8.84e-2)" "unprognostic (1.79e-2)" "unprognostic (2.36e-3)" "unprognostic (4.38e-3)" "unprognostic (1.06e-2)" "unprognostic (3.73e-1)" "unprognostic (1.07e-2)" "potential prognostic unfavorable (2.64e-4)" "unprognostic (2.03e-2)" "unprognostic (2.10e-1)" "unprognostic (2.70e-1)" "unprognostic (3.58e-1)" "unprognostic (8.13e-3)" "unprognostic (1.59e-2)" "unprognostic (4.27e-3)" "unprognostic (6.34e-2)" "unprognostic (8.02e-3)" "unprognostic (1.44e-1)" COL5A2 ENSG00000204262 "Collagen type V alpha 2 chain" P05997 2 189031898-189225312 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 355.9;Decidual stromal cells: 221.2;Endometrial stromal cells: 385.8;Fibro-adipogenic progenitors: 612.0;Fibroblasts: 415.1;Hepatic stellate cells: 626.1;Leydig cells: 288.2;Myosatellite cells: 307.1;Pericytes: 300.3;Pituicytes/FSCs: 188.3;Schwann cells: 254.4" "Cell type enhanced" "Detected in all" "hippocampal CA1-3: 684.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 482.1;testis cancer: 343.6" "Adipose subcutaneous - Adipose progenitor cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblasts_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblasts_1, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" "No annotated function" NA NA 870000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 29: Forebrain - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 108: Fibroblasts - ECM organization" "unprognostic (1.65e-1)" "unprognostic (1.54e-1)" "unprognostic (1.37e-1)" "unprognostic (1.92e-2)" "unprognostic (6.86e-2)" "unprognostic (2.76e-1)" "unprognostic (1.97e-1)" "unprognostic (8.17e-3)" "unprognostic (8.81e-2)" "unprognostic (4.40e-2)" "unprognostic (1.95e-1)" "unprognostic (5.99e-2)" "potential prognostic unfavorable (1.60e-10)" "unprognostic (3.62e-2)" "unprognostic (4.18e-2)" "unprognostic (1.40e-3)" "unprognostic (1.94e-2)" "unprognostic (2.47e-2)" "unprognostic (1.25e-1)" "unprognostic (1.63e-2)" "potential prognostic unfavorable (3.84e-6)" "unprognostic (2.28e-2)" "unprognostic (2.38e-1)" "unprognostic (1.65e-1)" "unprognostic (3.35e-1)" "unprognostic (3.41e-3)" "unprognostic (6.54e-2)" "potential prognostic unfavorable (9.32e-4)" "unprognostic (2.79e-2)" "unprognostic (2.74e-2)" "unprognostic (1.45e-1)" COL5A3 ENSG00000080573 "Collagen type V alpha 3 chain" P25940 19 9959561-10010504 "Cancer-related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 96.9;Astrocytes: 539.1;Bergmann glia: 148.2;Choroid plexus epithelial cells: 163.9;Ependymal cells: 109.1;Fibro-adipogenic progenitors: 99.9;Fibroblasts: 72.9;Hepatic stellate cells: 161.4;Pericytes: 241.1;Retinal bipolar cells: 109.9;Rod photoreceptor cells: 76.2;Schwann cells: 81.5" "Cell type enhanced" "Detected in many" "astrocyte: 404.1;choroid plexus epithelial cell: 165.2;pericyte: 222.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 9.2;Sarcoma: 8.1;skin cancer: 7.1" "Adrenal gland - Fibroblasts, Breast - Adipocytes (Breast), Kidney - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA041695, HPA048256" Approved Approved "Plasma membrane" "Secreted to extracellular matrix" "No annotated function" NA NA 220000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 53: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 110: Mural cells - ECM organization" "Plasma membrane" "HPA041695: , HPA048256: " "unprognostic (2.48e-1)" "unprognostic (7.62e-2)" "unprognostic (2.72e-1)" "unprognostic (1.09e-2)" "unprognostic (8.38e-2)" "unprognostic (3.72e-1)" "unprognostic (7.65e-2)" "unprognostic (1.20e-2)" "unprognostic (1.91e-1)" "unprognostic (3.93e-2)" "unprognostic (3.67e-2)" "unprognostic (1.51e-2)" "potential prognostic unfavorable (2.26e-8)" "unprognostic (5.49e-2)" "unprognostic (1.35e-2)" "unprognostic (2.52e-2)" "potential prognostic unfavorable (5.77e-4)" "unprognostic (1.88e-1)" "unprognostic (1.30e-1)" "unprognostic (6.56e-2)" "unprognostic (1.34e-3)" "unprognostic (2.67e-2)" "unprognostic (3.38e-2)" "unprognostic (2.88e-1)" "unprognostic (3.43e-1)" "unprognostic (1.11e-1)" "unprognostic (3.22e-1)" "unprognostic (2.23e-2)" "unprognostic (1.27e-2)" "unprognostic (2.68e-2)" "unprognostic (5.80e-2)" COL6A1 ENSG00000142156 "Collagen type VI alpha 1 chain" P12109 21 45981770-46005050 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes, Congenital muscular dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 599.8;Endometrial stromal cells: 531.5;Fibro-adipogenic progenitors: 318.9;Fibroblasts: 743.2;Gonadotrophs: 325.7;Hepatic stellate cells: 1065.0;Leydig cells: 402.7;Ovarian stromal cells: 256.4;Pericytes: 439.3;Peritubular myoid cells: 269.5;Smooth muscle cells: 336.0" "Cell type enhanced" "Detected in all" "fibroblast: 299.8;pericyte: 248.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Brain cancer: 520.5" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Adrenal gland - Fibroblasts, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblasts_2, Pituitary gland - Gonadotropes, Skeletal muscle - Fibroblasts, Skin - Fibroblasts_1, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 81.4" "HPA019142, HPA029401" Enhanced Approved Cytosol "Secreted to extracellular matrix" "Cell adhesion" NA NA 68000000 "Cluster 75: Ovary - Mixed function" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 25 Cytosol "HPA019142: , HPA029401: " "unprognostic (3.87e-2)" "unprognostic (2.71e-1)" "unprognostic (1.31e-1)" "unprognostic (1.96e-2)" "unprognostic (1.55e-1)" "unprognostic (3.99e-1)" "unprognostic (6.68e-2)" "potential prognostic unfavorable (5.74e-4)" "unprognostic (5.43e-1)" "unprognostic (5.82e-2)" "unprognostic (8.17e-2)" "unprognostic (1.24e-2)" "unprognostic (1.06e-2)" "unprognostic (3.10e-1)" "unprognostic (5.16e-3)" "unprognostic (1.14e-1)" "unprognostic (1.34e-2)" "unprognostic (1.65e-1)" "unprognostic (1.52e-1)" "unprognostic (1.77e-2)" "unprognostic (5.35e-2)" "unprognostic (6.80e-3)" "unprognostic (3.38e-2)" "unprognostic (2.99e-1)" "unprognostic (7.70e-2)" "unprognostic (8.20e-3)" "unprognostic (2.36e-3)" "unprognostic (2.30e-2)" "unprognostic (4.30e-2)" "potential prognostic unfavorable (1.67e-4)" "unprognostic (7.00e-2)" COL6A2 ENSG00000142173 "Collagen type VI alpha 2 chain" P12110 21 46098112-46132848 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Congenital muscular dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Decidual stromal cells: 1279.3;Endometrial stromal cells: 498.8;Fibro-adipogenic progenitors: 384.4;Fibroblasts: 1238.3;Hepatic stellate cells: 916.6;Leydig cells: 746.7;Ovarian stromal cells: 425.3;Pericytes: 723.9;Peritubular myoid cells: 543.3;Smooth muscle cells: 797.3;Vascular smooth muscle cells: 502.8" "Group enriched" "Detected in many" 9 "ependymal cell: 95.5;fibroblast: 301.2;pericyte: 243.9;vascular associated smooth muscle cell: 256.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "gdT-cell: 4.5;MAIT T-cell: 3.1;memory CD8 T-cell: 2.4;naive CD8 T-cell: 1.2" "Lineage enriched" "Detected in single" 13 "T-cells: 4.5" "Cancer enhanced" "Detected in many" "Brain cancer: 574.1" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Adrenal gland - Fibroblasts, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts, Skin - Fibroblasts_1, Skin - Fibroblasts_2, Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 64.8" "HPA007029, HPA030920, HPA038799" Enhanced Uncertain "Plasma membrane,Cytosol" "Secreted to extracellular matrix" "Cell adhesion" NA NA 8700000 "Cluster 1: T-cells - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" Cytosol "Plasma membrane" "HPA007029: , HPA030920: , HPA038799: " "unprognostic (6.73e-2)" "unprognostic (2.43e-1)" "unprognostic (5.51e-2)" "unprognostic (5.87e-3)" "unprognostic (1.44e-1)" "unprognostic (2.56e-1)" "unprognostic (3.76e-2)" "unprognostic (1.66e-3)" "unprognostic (2.05e-1)" "unprognostic (2.63e-2)" "potential prognostic unfavorable (1.52e-4)" "unprognostic (1.23e-2)" "potential prognostic unfavorable (2.45e-4)" "unprognostic (2.49e-1)" "unprognostic (9.53e-3)" "unprognostic (2.08e-2)" "unprognostic (2.58e-2)" "unprognostic (1.23e-1)" "unprognostic (1.96e-1)" "unprognostic (6.79e-3)" "unprognostic (1.14e-1)" "unprognostic (5.00e-2)" "unprognostic (2.19e-1)" "unprognostic (1.75e-1)" "unprognostic (8.50e-2)" "unprognostic (5.62e-3)" "unprognostic (2.26e-2)" "unprognostic (2.49e-2)" "unprognostic (1.06e-1)" "unprognostic (5.15e-3)" "unprognostic (4.34e-2)" COL6A3 ENSG00000163359 "Collagen type VI alpha 3 chain" P12111 2 237324003-237414328 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Protease inhibitor, Serine protease inhibitor" "Congenital muscular dystrophy, Disease variant, Dystonia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 391.7" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 399.8;Endometrial stromal cells: 433.5;Fibro-adipogenic progenitors: 864.6;Fibroblasts: 914.5;Hepatic stellate cells: 413.1;Leydig cells: 521.1;Ovarian stromal cells: 233.3;Pericytes: 312.0;Peritubular myoid cells: 158.0;Smooth muscle cells: 144.2" "Group enriched" "Detected in many" 9 "fibroblast: 211.5;hippocampal dentate gyrus: 63.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 441.4;Sarcoma: 220.8" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Minor Salivary Gland - Macrophages, Skin - Fibroblasts_2" "Region enhanced" "Detected in some" "basal ganglia: 4.5" "Region enriched" "Detected in many" 4 "spinal cord: 18.1" "HPA010007, HPA010080" Supported Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" "Cell adhesion" NA NA 370000000 "Cluster 75: Ovary - Mixed function" "Cluster 29: Forebrain - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" "Endoplasmic reticulum" Vesicles "HPA010007: , HPA010080: " "unprognostic (2.82e-2)" "unprognostic (7.66e-2)" "unprognostic (9.79e-2)" "unprognostic (4.38e-3)" "unprognostic (1.33e-1)" "unprognostic (2.46e-1)" "unprognostic (5.85e-2)" "unprognostic (1.37e-2)" "unprognostic (2.04e-1)" "unprognostic (2.07e-3)" "unprognostic (2.38e-2)" "unprognostic (1.30e-1)" "potential prognostic unfavorable (4.31e-7)" "unprognostic (3.86e-2)" "unprognostic (3.26e-1)" "unprognostic (2.30e-1)" "unprognostic (5.30e-3)" "unprognostic (5.04e-2)" "unprognostic (2.28e-1)" "unprognostic (1.67e-2)" "unprognostic (1.61e-3)" "unprognostic (9.51e-2)" "unprognostic (3.12e-2)" "unprognostic (2.23e-1)" "unprognostic (3.22e-1)" "unprognostic (9.45e-3)" "unprognostic (2.86e-2)" "unprognostic (2.34e-2)" "unprognostic (1.09e-2)" "unprognostic (1.07e-2)" "unprognostic (4.24e-2)" COL6A5 "COL29A1, FLJ35880, VWA4" ENSG00000172752 "Collagen type VI alpha 5 chain" 3 130345516-130484846 "Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lung: 5.5;skin 1: 4.5" "Group enriched" "Detected in some" 4 "Early spermatids: 8.4;Erythrocyte progenitors: 3.3;Fibroblasts: 3.7;Late primary spermatocytes: 4.9;Late spermatids: 12.1;Megakaryocyte-Erythroid progenitors: 10.4;Other brain neurons: 5.7;Undifferentiated spermatogonia: 8.1" "Cell type enriched" "Detected in single" 29 "thalamic excitatory: 27.9" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "midbrain: 3.3;thalamus: 1.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "lymphoma: 4.3" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA043138 Uncertain "Secreted in other tissues" NA NA "Cluster 58: Skin - Keratinization" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 108: Fibroblasts - ECM organization" 1 "HPA043138: " "unprognostic (2.90e-2)" "unprognostic (3.70e-2)" COL6A6 ENSG00000206384 "Collagen type VI alpha 6 chain" A6NMZ7 3 130517177-130677044 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "parathyroid gland: 98.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 138.0;Cone photoreceptor cells: 37.3;Fibro-adipogenic progenitors: 84.2;Fibroblasts: 37.2;Lactotrophs: 265.2;Mesothelial cells: 49.6;Myonuclei: 37.8;Other brain neurons: 74.0;Somatotrophs: 117.6" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in single" "Testicular Germ Cell Tumor (TCGA): 1.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Neuroblastoma: 3.5;testis cancer: 1.2" "Adrenal gland - Smooth muscle cells, Minor Salivary Gland - Fibroblasts" "Not detected" "Not detected" "Region enriched" "Detected in single" 15 "spinal cord: 13.2" HPA045239 Uncertain "Secreted to extracellular matrix" "Cell adhesion" NA NA 450000 "Cluster 69: Parathyroid gland - Mixed function" "Cluster 33: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" "HPA045239: " "unprognostic (1.64e-2)" "unprognostic (4.80e-2)" "unprognostic (6.00e-2)" "unprognostic (1.63e-1)" COL7A1 "EBD1, EBDCT, EBR1" ENSG00000114270 "Collagen type VII alpha 1 chain" Q02388 3 48564073-48595329 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Protease inhibitor, Serine protease inhibitor" "Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 92.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 82.7;Basal prostatic cells: 64.3;Endometrial stromal cells: 46.8;Epididymal basal cells: 108.0;Medullary thymic epithelial cells: 36.0;Ocular epithelial cells: 34.5;Podocytes: 51.4;Respiratory basal cells: 50.1;Salivary basal cells: 37.0" "Cell type enhanced" "Detected in many" "fibroblast: 64.9" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 47.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Minor Salivary Gland - Minor salivary gland basal cells" "CAB016357, HPA018877, HPA042420" Enhanced Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" "Cell adhesion" NA NA "Cluster 58: Skin - Keratinization" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 72: Neuronal - Signal transduction" "Cluster 26: Keratinocytes - Keratinization" 6 "Endoplasmic reticulum" Vesicles "CAB016357: , HPA018877: , HPA042420: " "unprognostic (3.17e-2)" "unprognostic (1.38e-1)" "unprognostic (4.52e-3)" "unprognostic (1.29e-1)" "unprognostic (1.13e-1)" "unprognostic (2.39e-2)" "unprognostic (6.18e-2)" "unprognostic (7.16e-3)" "unprognostic (6.96e-2)" "unprognostic (7.83e-3)" "unprognostic (1.85e-2)" "unprognostic (7.75e-2)" "unprognostic (4.26e-1)" "potential prognostic unfavorable (7.61e-4)" "unprognostic (6.66e-3)" "unprognostic (1.26e-1)" "unprognostic (1.12e-1)" "unprognostic (1.66e-1)" "unprognostic (1.05e-1)" "validated prognostic unfavorable (1.55e-4)" "validated prognostic unfavorable (2.78e-4)" "unprognostic (1.78e-2)" "unprognostic (1.27e-1)" "unprognostic (5.35e-2)" "unprognostic (4.50e-2)" "unprognostic (1.89e-1)" "unprognostic (1.36e-1)" "unprognostic (2.71e-1)" "unprognostic (2.31e-1)" COL8A1 "C3orf7, MGC9568" ENSG00000144810 "Collagen type VIII alpha 1 chain" P27658 3 99638475-99799226 "Plasma proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "blood vessel: 226.1" "Cell type enhanced" "Detected in many" "Adipocytes: 342.2;Alveolar cells type 1: 971.5;Alveolar cells type 2: 325.5;Bergmann glia: 312.2;Ependymal cells: 458.3;Epicardial cells: 423.0;Fibro-adipogenic progenitors: 273.0;Mesothelial cells: 973.6;Pituicytes/FSCs: 891.6;Retinal pigment epithelial cells: 873.9" "Cell type enhanced" "Detected in many" "Bergmann glia: 302.0;ependymal cell: 408.2" "Cancer enhanced" "Detected in all" "Thyroid Carcinoma (TCGA): 84.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 91.3;Kidney cancer: 98.2;thyroid cancer: 96.2" "Adipose visceral - Mesothelial cells, Heart muscle - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Spleen - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA053107 Enhanced Approved Vesicles "Secreted to extracellular matrix" "Cell adhesion" NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 46: Brainstem - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 54 Vesicles "HPA053107: " "unprognostic (1.71e-3)" "unprognostic (6.16e-2)" "unprognostic (5.25e-2)" "unprognostic (1.40e-1)" "unprognostic (3.75e-3)" "unprognostic (1.58e-2)" "unprognostic (3.08e-2)" "potential prognostic unfavorable (4.80e-5)" "unprognostic (1.33e-1)" "unprognostic (1.20e-3)" "unprognostic (4.39e-3)" "unprognostic (5.22e-2)" "unprognostic (4.62e-3)" "unprognostic (4.21e-2)" "unprognostic (4.15e-2)" "unprognostic (3.80e-1)" "potential prognostic unfavorable (4.01e-4)" "unprognostic (5.08e-2)" "unprognostic (5.04e-2)" "unprognostic (8.63e-3)" "potential prognostic unfavorable (2.70e-5)" "unprognostic (2.99e-2)" "unprognostic (1.83e-1)" "unprognostic (1.53e-1)" "unprognostic (1.43e-1)" "unprognostic (1.98e-3)" "unprognostic (5.15e-2)" "unprognostic (2.40e-3)" "unprognostic (1.67e-1)" "unprognostic (1.79e-2)" "unprognostic (1.30e-2)" COL8A2 "FECD, FECD1, PPCD, PPCD2" ENSG00000171812 "Collagen type VIII alpha 2 chain" P25067 1 36095239-36125222 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion" "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 37.4" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 37.9;Choroid plexus epithelial cells: 20.8;Fibroblasts: 13.8;Medullary thymic epithelial cells: 12.0;Microglia: 26.0;Retinal pigment epithelial cells: 72.5;Salivary myoepithelial cells: 20.7" "Group enriched" "Detected in some" 7 "central nervous system macrophage: 30.5;cerebellar inhibitory: 24.3;choroid plexus epithelial cell: 22.7;ependymal cell: 7.8;fibroblast: 14.1" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 38.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 4.5" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Fibroblasts, Breast - Breast myoepithelial cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "spinal cord: 4.1" HPA049788 Uncertain Uncertain "Golgi apparatus" "Secreted to extracellular matrix" "Cell adhesion" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 8: Immune cells - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" "Golgi apparatus" "HPA049788: " "unprognostic (3.28e-3)" "unprognostic (1.83e-1)" "unprognostic (5.20e-2)" "unprognostic (8.69e-3)" "unprognostic (7.89e-2)" "unprognostic (2.42e-1)" "unprognostic (9.28e-2)" "potential prognostic unfavorable (3.40e-4)" "unprognostic (1.23e-3)" "unprognostic (2.51e-3)" "unprognostic (1.50e-2)" "unprognostic (2.96e-2)" "unprognostic (4.76e-2)" "unprognostic (4.13e-2)" "unprognostic (4.45e-2)" "unprognostic (1.60e-1)" "unprognostic (1.03e-1)" "validated prognostic unfavorable (1.50e-4)" "validated prognostic unfavorable (2.48e-4)" "unprognostic (5.45e-2)" "unprognostic (6.36e-3)" "unprognostic (4.10e-1)" "unprognostic (8.90e-2)" "unprognostic (2.88e-3)" "unprognostic (1.04e-1)" "unprognostic (8.03e-3)" "unprognostic (1.07e-1)" "unprognostic (7.51e-2)" "unprognostic (3.06e-1)" COL9A1 ENSG00000112280 "Collagen type IX alpha 1 chain" P20849 6 70216040-70303084 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Deafness, Disease variant, Stickler syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.4;choroid plexus: 23.9;prostate: 10.8" "Group enriched" "Detected in some" 4 "Choroid plexus epithelial cells: 502.2;Oligodendrocyte progenitor cells: 339.5" "Group enriched" "Detected in many" 7 "choroid plexus epithelial cell: 530.5;committed oligodendrocyte precursor: 282.8;oligodendrocyte precursor cell: 406.9" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 16 "choroid plexus: 91.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Rhabdoid: 2.8;Sarcoma: 2.1;skin cancer: 1.1" "Colon - Enteric glia cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA074749 Enhanced "Secreted to extracellular matrix" "No annotated function" NA NA 55000 "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 5 "HPA074749: " "unprognostic (1.53e-2)" "unprognostic (9.30e-2)" "unprognostic (1.08e-1)" "unprognostic (1.39e-1)" "unprognostic (3.52e-2)" "unprognostic (7.20e-3)" "unprognostic (3.26e-1)" "unprognostic (1.08e-1)" "unprognostic (5.69e-3)" "unprognostic (8.03e-2)" "unprognostic (2.69e-2)" "unprognostic (2.98e-1)" "unprognostic (2.64e-2)" "unprognostic (1.08e-1)" "unprognostic (2.59e-1)" "unprognostic (8.26e-2)" COL9A2 "EDM2, MED" ENSG00000049089 "Collagen type IX alpha 2 chain" Q14055 1 40300489-40317813 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Deafness, Disease variant, Dwarfism, Stickler syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 135.9;pituitary gland: 106.4" "Cell type enhanced" "Detected in many" "Epididymal clear cells: 167.4;Müller glia: 424.7;Oligodendrocyte progenitor cells: 124.0;Oligodendrocytes: 137.3;Pituicytes/FSCs: 61.4;Pituitary stem cells: 85.0;Retinal pigment epithelial cells: 68.2;Somatotrophs: 107.4;Thyrotrophs: 178.6" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 150.7;oligodendrocyte: 139.3;oligodendrocyte precursor cell: 140.2" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 142.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "eosinophil: 3.2;myeloid DC: 1.2" "Group enriched" "Detected in many" 6 "dendritic cells: 1.2;granulocytes: 3.2" "Low cancer specificity" "Detected in many" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "HPA056316, HPA075286" Supported Approved Vesicles "Secreted to extracellular matrix" "No annotated function" NA NA 6500 "Cluster 22: Eosinophils - Transcription" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 6: Non-specific - Immune response" "Cluster 11: Neuronal - Sensory perception" "Cluster 11: Muller glia cells - Retinal homeostasis" 4 Vesicles "HPA056316: , HPA075286: " "unprognostic (1.26e-2)" "unprognostic (9.44e-3)" "unprognostic (6.86e-2)" "unprognostic (2.03e-1)" "unprognostic (7.16e-2)" "unprognostic (9.48e-2)" "unprognostic (1.22e-1)" "unprognostic (2.03e-1)" "unprognostic (4.58e-3)" "unprognostic (4.42e-1)" "potential prognostic unfavorable (2.06e-4)" "unprognostic (4.20e-2)" "unprognostic (1.61e-1)" "unprognostic (2.12e-2)" "unprognostic (2.41e-1)" "unprognostic (1.89e-2)" "unprognostic (4.85e-2)" "unprognostic (1.01e-1)" "unprognostic (1.30e-1)" "unprognostic (1.75e-1)" "unprognostic (1.59e-2)" "unprognostic (4.08e-3)" "unprognostic (2.69e-2)" "unprognostic (3.54e-1)" "unprognostic (3.68e-1)" "unprognostic (6.40e-2)" "unprognostic (3.21e-1)" "unprognostic (1.48e-2)" "unprognostic (1.67e-1)" "unprognostic (5.82e-2)" "unprognostic (3.61e-1)" COL9A3 "DJ885L7.4.1, EDM3, FLJ90759, IDD, MED" ENSG00000092758 "Collagen type IX alpha 3 chain" Q14050 20 62816244-62841159 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Deafness, Disease variant, Dwarfism, Stickler syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 70.9" "Cell type enriched" "Detected in many" 4 "Late spermatids: 683.9" "Group enriched" "Detected in many" 4 "choroid plexus epithelial cell: 44.7;committed oligodendrocyte precursor: 99.8;oligodendrocyte: 88.0;oligodendrocyte precursor cell: 113.2" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 77.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 154.3" "Adipose subcutaneous - Smooth muscle cells, Colon - Enteric glia cells, Liver - Hepatocytes, Stomach - Fibroblasts, Testis - Late spermatids" "Low region specificity" "Detected in all" "HPA040125, HPA058323" Supported Approved "Nucleoplasm,Intermediate filaments" "Secreted to extracellular matrix" "No annotated function" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 5 Nucleoplasm "Intermediate filaments" "HPA040125: , HPA058323: " "unprognostic (5.62e-2)" "unprognostic (7.03e-3)" "unprognostic (3.50e-2)" "unprognostic (1.13e-1)" "unprognostic (4.50e-2)" "unprognostic (3.87e-2)" "unprognostic (4.22e-2)" "unprognostic (9.45e-2)" "unprognostic (5.99e-2)" "unprognostic (1.75e-1)" "unprognostic (2.65e-2)" "unprognostic (6.71e-3)" "unprognostic (2.96e-3)" "unprognostic (7.22e-3)" "unprognostic (2.57e-1)" "unprognostic (3.90e-3)" "unprognostic (5.93e-2)" "unprognostic (8.01e-3)" "unprognostic (2.94e-1)" "unprognostic (1.22e-1)" "unprognostic (7.16e-2)" "unprognostic (1.91e-1)" "unprognostic (7.51e-2)" "unprognostic (6.30e-2)" "unprognostic (3.83e-2)" COLEC10 "CL-10, CL-L1" ENSG00000184374 "Collectin subfamily member 10" Q9Y6Z7 8 118995452-119108455 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 61.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 15.9;Hepatic stellate cells: 83.9;Loop of henle epithelial cells: 78.3;Oocytes: 50.7;Papillary tip epithelial cells: 22.8;Renal collecting duct principal cells: 20.9;Renal connecting tubule cells: 29.5" "Cell type enhanced" "Detected in many" "mammillary body: 29.7" "Cancer enhanced" "Detected in some" "Kidney Renal Papillary Cell Carcinoma (TCGA): 2.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney cancer: 7.8;Neuroblastoma: 8.8" "Liver - Hepatic stellate cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted to blood" "No annotated function" NA NA 1870000000 71000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" "unprognostic (9.75e-2)" "unprognostic (3.05e-1)" "potential prognostic favorable (8.74e-4)" "unprognostic (2.60e-3)" COLEC11 "CL-11, CL-K1, MGC3279" ENSG00000118004 "Collectin subfamily member 11" Q9BWP8 2 3594832-3644644 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 50.7;liver: 108.9;ovary: 50.7" "Cell type enriched" "Detected in many" 5 "Hepatic stellate cells: 813.3" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 31.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "Neuroblastoma: 27.6" "Adrenal gland - Fibroblasts, Colon - Enteric glia cells, Kidney - Proximal tubular cells, Liver - Hepatic stellate cells, Pituitary gland - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA035241 Uncertain "Secreted to blood" "Developmental protein" NA NA 299000000 250000000 "Cluster 76: Non-specific - Metabolism" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 94: Gonadal somatic cells - Mixed function" 2 "HPA035241: " "unprognostic (1.15e-1)" "unprognostic (4.79e-2)" "unprognostic (4.49e-1)" "unprognostic (6.03e-2)" "unprognostic (2.61e-3)" "unprognostic (1.44e-1)" "unprognostic (3.04e-2)" "unprognostic (5.28e-2)" "unprognostic (2.61e-2)" "unprognostic (7.97e-2)" "unprognostic (5.05e-3)" "unprognostic (3.16e-2)" "unprognostic (1.63e-1)" "unprognostic (6.71e-3)" "unprognostic (5.34e-3)" "potential prognostic favorable (1.51e-4)" "unprognostic (2.96e-1)" "unprognostic (5.12e-2)" "unprognostic (2.21e-2)" "unprognostic (2.13e-1)" "unprognostic (7.24e-2)" "unprognostic (1.01e-1)" "unprognostic (1.94e-1)" "unprognostic (2.60e-1)" "unprognostic (1.41e-1)" "unprognostic (6.38e-3)" "unprognostic (1.61e-1)" "unprognostic (1.34e-1)" "unprognostic (2.88e-1)" "unprognostic (2.47e-1)" "unprognostic (9.03e-2)" COLEC12 "CL-P1, SCARA4, SRCL" ENSG00000158270 "Collectin subfamily member 12" Q5KU26 18 316737-500722 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 25.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 194.0;Bergmann glia: 544.4;Choroid plexus epithelial cells: 208.1;Cytotrophoblasts: 496.5;Ependymal cells: 293.3;Fibro-adipogenic progenitors: 253.3;Fibroblasts: 216.6;Hofbauer cells: 863.2;Lymphatic endothelial cells: 383.4;Macrophages: 387.9;Müller glia: 364.4;Prostatic glandular cells: 229.5;Retinal pigment epithelial cells: 294.1;Rod photoreceptor cells: 192.0;Syncytiotrophoblasts: 220.1" "Group enriched" "Detected in many" 4 "Bergmann glia: 574.4;fibroblast: 2125.1;pericyte: 2132.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 9.1;Rhabdoid: 14.8" "Adrenal gland - Macrophages, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Vascular endothelial cells, Skeletal muscle - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA047917, HPA071056" Enhanced Approved "Golgi apparatus,Vesicles,Cell Junctions" NA NA 1700000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 46: Brainstem - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 6 "Golgi apparatus, Vesicles" "Cell Junctions" "HPA047917: , HPA071056: " "potential prognostic favorable (2.13e-4)" "unprognostic (6.91e-2)" "unprognostic (1.80e-1)" "unprognostic (5.36e-2)" "unprognostic (5.67e-2)" "unprognostic (1.97e-1)" "unprognostic (8.33e-2)" "unprognostic (2.42e-1)" "unprognostic (4.74e-2)" "unprognostic (1.92e-1)" "unprognostic (1.65e-3)" "unprognostic (7.48e-2)" "unprognostic (9.33e-2)" "unprognostic (3.93e-2)" "unprognostic (5.76e-2)" "unprognostic (7.79e-2)" "unprognostic (4.19e-3)" "unprognostic (2.05e-1)" "unprognostic (1.74e-2)" "potential prognostic unfavorable (3.53e-4)" "unprognostic (1.60e-2)" "unprognostic (1.64e-1)" "unprognostic (2.47e-1)" "unprognostic (3.88e-2)" "unprognostic (2.46e-1)" "unprognostic (1.27e-1)" "unprognostic (4.70e-3)" "unprognostic (1.27e-1)" "unprognostic (3.98e-3)" "unprognostic (2.08e-1)" COLGALT1 "FLJ22329, GLT25D1" ENSG00000130309 "Collagen beta(1-O)galactosyltransferase 1" Q8NBJ5 19 17555649-17583162 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 109.3;Hofbauer cells: 120.5;Kupffer cells: 93.3;Macrophages: 96.8;monocytes: 100.6;pDCs: 76.7" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 99.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 23.3;eosinophil: 11.2;intermediate monocyte: 26.6;myeloid DC: 17.1;non-classical monocyte: 19.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047821, HPA048254" Approved Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" Enzyme No No 6300 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 12: Non-specific - Vasculature" "Cluster 23: Non-specific - Transcription" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 16 Vesicles "Golgi apparatus" "HPA047821: , HPA048254: " "unprognostic (1.72e-1)" "unprognostic (7.48e-2)" "unprognostic (2.36e-3)" "unprognostic (7.97e-2)" "unprognostic (1.05e-2)" "unprognostic (8.32e-2)" "unprognostic (2.90e-2)" "unprognostic (5.59e-2)" "unprognostic (5.39e-2)" "unprognostic (2.17e-3)" "unprognostic (2.76e-3)" "unprognostic (5.49e-2)" "unprognostic (1.91e-3)" "potential prognostic unfavorable (2.74e-4)" "unprognostic (1.71e-2)" "unprognostic (2.83e-1)" "unprognostic (3.87e-2)" "unprognostic (1.61e-2)" "unprognostic (4.08e-1)" "unprognostic (8.77e-3)" "unprognostic (2.85e-2)" "unprognostic (1.54e-1)" "unprognostic (3.50e-1)" "unprognostic (4.69e-2)" "unprognostic (1.17e-1)" "unprognostic (6.33e-2)" "unprognostic (2.09e-1)" "unprognostic (2.98e-2)" "unprognostic (1.09e-1)" COLGALT2 "C1orf17, GLT25D2, KIAA0584" ENSG00000198756 "Collagen beta(1-O)galactosyltransferase 2" Q8IYK4 1 183929854-184037729 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.7" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 117.0;Astrocytes: 57.1;Brain excitatory neurons: 64.1;Early spermatids: 70.8;Fibro-adipogenic progenitors: 128.4;Late spermatids: 106.2;Oligodendrocyte progenitor cells: 178.4;Oligodendrocytes: 414.7;Retinal amacrine cells: 56.5" "Cell type enhanced" "Detected in all" "oligodendrocyte: 576.5" "Group enriched" "Detected in many" 4 "Glioblastoma Multiforme (TCGA): 24.8;Skin Cutaneous Melanoma (TCGA): 10.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 30 "basophil: 11.1" "Lineage enriched" "Detected in single" 30 "granulocytes: 11.1" "Cancer enhanced" "Detected in many" "Rhabdoid: 18.5" "Adrenal gland - Adrenal medulla cells, Prostate - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031749, HPA031750" Approved Approved Nucleoplasm,Vesicles "Intracellular and membrane" Enzyme NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 80: Oligodendrocytes - Myelination" 13 Nucleoplasm Vesicles "HPA031749: , HPA031750: " "unprognostic (1.26e-1)" "unprognostic (3.22e-2)" "unprognostic (2.68e-1)" "unprognostic (1.55e-2)" "unprognostic (1.49e-1)" "unprognostic (5.14e-2)" "unprognostic (1.78e-3)" "unprognostic (3.79e-1)" "potential prognostic favorable (3.35e-4)" "unprognostic (5.21e-2)" "unprognostic (5.61e-2)" "unprognostic (2.60e-1)" "unprognostic (2.50e-2)" "unprognostic (1.04e-1)" "unprognostic (2.63e-2)" "unprognostic (1.25e-1)" COLQ EAD ENSG00000206561 "Collagen like tail subunit of asymmetric acetylcholinesterase" Q9Y215 3 15450133-15521751 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Neurotransmitter degradation" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 14.2;heart muscle: 16.8" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 165.8;Ependymal cells: 137.9;Myonuclei: 211.7;NK-cells: 87.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "MAIT T-cell: 61.0" "Lineage enriched" "Detected in many" 34 "T-cells: 61.0" "Low cancer specificity" "Detected in some" "Colon - Enteric glia cells, Spleen - NK-cells (Spleen)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA045876 Approved "Plasma membrane,Cell Junctions" "Secreted to blood" Other NA NA "Cluster 1: T-cells - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 17: Choroid plexus - Cilium" "Cluster 34: Testis cancer - Unknown function" "Cluster 55: Myocytes - Oxidative muscle function" 3 "Plasma membrane" "Cell Junctions" "HPA045876: " "unprognostic (1.09e-1)" "unprognostic (1.31e-1)" "unprognostic (7.04e-3)" "unprognostic (4.14e-2)" "unprognostic (3.40e-3)" "unprognostic (1.49e-1)" "unprognostic (2.71e-2)" "unprognostic (3.54e-2)" "unprognostic (1.65e-1)" "unprognostic (3.75e-2)" COMMD1 "C2orf5, MGC27155, MURR1" ENSG00000173163 "Copper metabolism domain containing 1" Q8N668 2 61888724-62147247 "Predicted intracellular proteins" "Protein transport, Transcription, Transcription regulation, Transport, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034633, HPA049223" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 35: Non-specific - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 144 Nucleoplasm Cytosol "HPA034633: , HPA049223: " "unprognostic (1.78e-3)" "unprognostic (3.23e-2)" "unprognostic (1.26e-2)" "potential prognostic favorable (3.80e-4)" "unprognostic (2.03e-1)" "unprognostic (2.70e-1)" "unprognostic (1.08e-1)" "unprognostic (3.89e-2)" "unprognostic (2.22e-2)" "unprognostic (2.44e-1)" "potential prognostic favorable (9.41e-6)" "unprognostic (5.87e-2)" "unprognostic (2.65e-1)" "potential prognostic unfavorable (7.84e-4)" "unprognostic (4.23e-2)" "unprognostic (2.45e-1)" "unprognostic (1.14e-1)" "unprognostic (5.50e-2)" "unprognostic (9.50e-2)" "unprognostic (8.04e-2)" "unprognostic (1.37e-1)" "unprognostic (6.95e-2)" "unprognostic (5.03e-2)" "unprognostic (1.71e-2)" "unprognostic (6.60e-2)" "unprognostic (1.45e-1)" "unprognostic (3.69e-2)" "unprognostic (1.12e-3)" "unprognostic (4.20e-2)" "unprognostic (4.49e-1)" "unprognostic (5.74e-2)" COMMD10 PTD002 ENSG00000145781 "COMM domain containing 10" Q9Y6G5 5 116085016-116412762 "Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045441, HPA054156" Approved Supported Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 22: Epididymis - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 54 Nucleoplasm "HPA045441: , HPA054156: " "unprognostic (4.46e-2)" "unprognostic (4.80e-2)" "unprognostic (1.07e-2)" "unprognostic (2.78e-1)" "unprognostic (8.94e-3)" "unprognostic (2.50e-2)" "unprognostic (4.85e-1)" "unprognostic (9.95e-2)" "unprognostic (6.98e-3)" "unprognostic (4.50e-2)" "potential prognostic favorable (3.52e-7)" "unprognostic (3.43e-2)" "unprognostic (1.23e-1)" "unprognostic (1.28e-2)" "unprognostic (5.22e-2)" "unprognostic (4.71e-2)" "unprognostic (1.90e-1)" "unprognostic (8.95e-2)" "unprognostic (9.07e-3)" "unprognostic (1.35e-1)" "unprognostic (2.61e-3)" "unprognostic (2.53e-1)" "unprognostic (4.39e-3)" "unprognostic (2.02e-1)" "unprognostic (1.37e-2)" "unprognostic (1.71e-1)" "unprognostic (8.35e-2)" "potential prognostic unfavorable (1.51e-4)" "unprognostic (2.15e-1)" "unprognostic (5.83e-2)" "unprognostic (1.71e-1)" COMMD2 HSPC042 ENSG00000114744 "COMM domain containing 2" Q86X83 3 149738472-149752495 "Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044190, HPA075248" Uncertain Uncertain Vesicles NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 7: Non-specific - Transcription" 85 Vesicles "HPA044190: , HPA075248: " "unprognostic (1.17e-1)" "unprognostic (1.17e-1)" "unprognostic (2.05e-1)" "unprognostic (7.95e-2)" "unprognostic (1.64e-1)" "unprognostic (3.24e-2)" "potential prognostic favorable (1.71e-4)" "unprognostic (5.56e-3)" "unprognostic (1.22e-1)" "unprognostic (2.62e-2)" "potential prognostic favorable (4.80e-6)" "unprognostic (1.37e-3)" "unprognostic (1.33e-2)" "potential prognostic unfavorable (1.85e-4)" "unprognostic (3.36e-3)" "unprognostic (3.35e-1)" "unprognostic (1.47e-1)" "unprognostic (4.59e-2)" "unprognostic (1.31e-1)" "unprognostic (4.22e-1)" "potential prognostic unfavorable (4.50e-4)" "validated prognostic unfavorable (7.48e-4)" "validated prognostic unfavorable (4.59e-4)" "unprognostic (6.92e-2)" "unprognostic (1.39e-1)" "unprognostic (1.03e-2)" "unprognostic (8.62e-3)" "unprognostic (1.87e-1)" "unprognostic (1.16e-1)" "unprognostic (9.02e-2)" "unprognostic (2.17e-1)" COMMD3 "BUP, C10orf8" ENSG00000148444 "COMM domain containing 3" Q9UBI1 10 22316386-22320306 "Predicted intracellular proteins" "Ion transport, Sodium transport, Transcription, Transcription regulation, Transport, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 290.1;Late primary spermatocytes: 81.5;Late spermatids: 67.1;Parietal cells: 54.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036584 Approved NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cellular respiration" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 67: Plasma cells - Plasma cell differentiation" 45 "HPA036584: " "unprognostic (1.59e-1)" "unprognostic (2.52e-1)" "unprognostic (7.27e-2)" "unprognostic (2.73e-1)" "unprognostic (4.72e-2)" "unprognostic (4.11e-2)" "unprognostic (7.28e-2)" "potential prognostic favorable (5.16e-5)" "unprognostic (1.65e-1)" "unprognostic (1.66e-1)" "potential prognostic favorable (4.56e-6)" "unprognostic (5.46e-2)" "potential prognostic favorable (6.01e-4)" "potential prognostic unfavorable (7.06e-8)" "unprognostic (1.11e-1)" "unprognostic (3.07e-2)" "unprognostic (8.45e-2)" "unprognostic (5.27e-2)" "unprognostic (9.14e-2)" "unprognostic (1.51e-1)" "unprognostic (1.80e-3)" "unprognostic (1.44e-1)" "unprognostic (8.52e-2)" "unprognostic (6.93e-2)" "unprognostic (7.32e-2)" "unprognostic (5.29e-2)" "unprognostic (2.45e-1)" "unprognostic (4.85e-2)" "unprognostic (1.34e-1)" "unprognostic (9.48e-2)" "unprognostic (1.42e-1)" COMMD3-BMI1 ENSG00000269897 "COMMD3-BMI1 readthrough" 10 22316388-22329542 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "retina: 9.4;testis: 5.5" "Cell type enhanced" "Detected in some" "Enterocytes: 1.8;Epididymal clear cells: 2.0;Epididymal efferent duct absorptive cells: 1.3;Epididymal principal cells: 1.2;Mast cells: 1.1;Parietal cells: 1.8;Plasma cells: 1.1;Thymic myoid cells: 1.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Myeloma: 11.6" "HPA030471, HPA030472, HPA036584" Uncertain Approved "Nucleoplasm,Nucleoli,Nuclear bodies,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 11: White matter - Signal transduction" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 67: Plasma cells - Plasma cell differentiation" 2 "Nuclear bodies" "Nucleoplasm, Nucleoli, Cytosol" "HPA030471: , HPA030472: , HPA036584: " "unprognostic (5.73e-1)" "unprognostic (2.15e-1)" "unprognostic (5.98e-1)" "potential prognostic unfavorable (5.52e-4)" "unprognostic (1.11e-2)" "unprognostic (5.86e-3)" "unprognostic (1.04e-1)" "unprognostic (6.65e-2)" "unprognostic (1.78e-1)" "unprognostic (5.05e-1)" "unprognostic (5.28e-1)" COMMD4 FLJ20452 ENSG00000140365 "COMM domain containing 4" Q9H0A8 15 75336020-75343224 "Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 181.3;Late primary spermatocytes: 166.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039935, HPA066957" Uncertain Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 21: Non-specific - Metabolism" "Cluster 58: Non-specific - Nuclear processes" "Cluster 27: Non-specific - Cell proliferation" 92 Cytosol "Vesicles, Plasma membrane" "HPA039935: , HPA066957: " "unprognostic (3.24e-2)" "unprognostic (3.79e-1)" "unprognostic (9.04e-2)" "potential prognostic favorable (8.69e-5)" "unprognostic (1.16e-1)" "unprognostic (1.89e-1)" "unprognostic (2.13e-2)" "unprognostic (5.89e-3)" "unprognostic (2.90e-1)" "unprognostic (9.29e-2)" "unprognostic (1.47e-1)" "unprognostic (1.59e-1)" "unprognostic (4.74e-2)" "unprognostic (1.02e-1)" "unprognostic (3.91e-3)" "unprognostic (2.48e-3)" "unprognostic (2.96e-2)" "unprognostic (1.87e-1)" "unprognostic (1.43e-2)" "unprognostic (3.98e-2)" "unprognostic (2.10e-3)" "unprognostic (2.43e-1)" "unprognostic (1.63e-1)" "unprognostic (1.52e-1)" "unprognostic (3.72e-2)" "unprognostic (1.71e-1)" "unprognostic (2.96e-1)" "unprognostic (6.31e-2)" "unprognostic (1.61e-1)" "unprognostic (2.90e-1)" "unprognostic (1.77e-1)" COMMD5 "FLJ13008, HCaRG, HT002" ENSG00000170619 "COMM domain containing 5" Q9GZQ3 8 144841042-144853736 "Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 95.3;Esophageal apical cells: 144.4;Hofbauer cells: 93.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046905 Supported Nucleoplasm,Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 84: Apical squamous epithelium - Cornification" 58 "Nucleoplasm, Cytosol" "HPA046905: " "unprognostic (3.07e-2)" "unprognostic (6.82e-3)" "unprognostic (4.50e-3)" "unprognostic (2.48e-1)" "unprognostic (1.29e-1)" "unprognostic (1.16e-1)" "unprognostic (3.06e-3)" "unprognostic (5.73e-2)" "unprognostic (1.58e-2)" "unprognostic (4.39e-3)" "unprognostic (5.05e-3)" "unprognostic (9.20e-2)" "unprognostic (4.32e-3)" "potential prognostic unfavorable (3.85e-4)" "unprognostic (2.11e-2)" "unprognostic (2.72e-1)" "unprognostic (3.80e-2)" "unprognostic (1.17e-1)" "unprognostic (2.79e-1)" "unprognostic (4.51e-2)" "unprognostic (1.07e-1)" "unprognostic (2.08e-1)" "unprognostic (3.24e-2)" "unprognostic (1.82e-1)" "unprognostic (1.87e-1)" "unprognostic (1.76e-1)" "unprognostic (2.14e-1)" "unprognostic (1.71e-1)" "unprognostic (1.69e-1)" "unprognostic (2.25e-1)" "unprognostic (1.00e-1)" COMMD6 Acrg ENSG00000188243 "COMM domain containing 6" Q7Z4G1 13 75525214-75549439 "Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Decidual stromal cells: 1072.5;Parietal cells: 1734.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 75: Ovary - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 19: Non-specific - Unknown function" "Cluster 15: Non-specific - Protein processing" 66 "unprognostic (2.23e-2)" "unprognostic (2.37e-1)" "unprognostic (2.18e-1)" "unprognostic (5.58e-2)" "unprognostic (1.96e-1)" "unprognostic (3.70e-2)" "unprognostic (2.26e-1)" "unprognostic (2.56e-1)" "unprognostic (1.71e-3)" "unprognostic (1.11e-1)" "potential prognostic favorable (5.81e-4)" "unprognostic (5.29e-3)" "unprognostic (2.19e-1)" "unprognostic (1.27e-2)" "unprognostic (8.31e-3)" "unprognostic (2.91e-1)" "potential prognostic unfavorable (9.62e-4)" "unprognostic (3.55e-1)" "unprognostic (2.82e-1)" "unprognostic (1.61e-1)" "unprognostic (4.33e-2)" "unprognostic (4.74e-2)" "unprognostic (1.69e-1)" "unprognostic (1.53e-1)" "unprognostic (1.88e-2)" "unprognostic (2.10e-1)" "unprognostic (8.87e-2)" "unprognostic (2.68e-1)" "unprognostic (8.44e-2)" "unprognostic (1.51e-1)" "unprognostic (2.54e-1)" COMMD7 "C20orf92, dJ1085F17.3" ENSG00000149600 "COMM domain containing 7" Q86VX2 20 32702699-32743467 "Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Oocytes: 4.6;Respiratory ionocytes: 2.5;Retinal pigment epithelial cells: 4.3;Schwann cells: 2.6;Tuft cells: 11.5" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054119 Approved Vesicles NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 62: Non-specific - Plasma proteins" "Cluster 95: Tuft cells - Chemosensory signaling" 17 Vesicles "HPA054119: " "unprognostic (1.07e-1)" "unprognostic (1.74e-2)" "unprognostic (1.72e-1)" "unprognostic (1.24e-1)" "unprognostic (2.29e-1)" "unprognostic (1.38e-1)" "unprognostic (1.39e-1)" "unprognostic (4.41e-1)" "unprognostic (1.21e-2)" "unprognostic (1.35e-2)" "potential prognostic favorable (7.55e-5)" "unprognostic (1.71e-1)" "unprognostic (3.42e-2)" "potential prognostic unfavorable (1.44e-4)" "unprognostic (1.88e-3)" "unprognostic (2.07e-1)" "unprognostic (1.66e-1)" "unprognostic (2.65e-1)" "unprognostic (1.41e-1)" "unprognostic (2.41e-1)" "unprognostic (3.29e-2)" "unprognostic (1.13e-2)" "unprognostic (2.12e-2)" "unprognostic (6.35e-2)" "unprognostic (1.25e-1)" "unprognostic (4.50e-2)" "unprognostic (4.09e-2)" "unprognostic (1.61e-2)" "unprognostic (2.96e-1)" "unprognostic (1.42e-1)" "unprognostic (3.47e-1)" COMMD8 FLJ20502 ENSG00000169019 "COMM domain containing 8" Q9NX08 4 47450787-47463702 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 148.4;Esophageal suprabasal cells: 154.1;Extravillous trophoblasts: 152.2;Late primary spermatocytes: 247.2;Oocytes: 119.7;Syncytiotrophoblasts: 131.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035887 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 72: Kidney - Transmembrane transport" "Cluster 21: Non-specific - Metabolism" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 97: Non-specific - Cellular respiration" 61 "Nucleoplasm, Cytosol" "HPA035887: " "unprognostic (3.00e-1)" "unprognostic (2.58e-2)" "unprognostic (6.96e-2)" "unprognostic (1.03e-1)" "unprognostic (6.31e-3)" "potential prognostic favorable (5.91e-6)" "unprognostic (7.04e-2)" "unprognostic (2.05e-2)" "unprognostic (1.20e-2)" "unprognostic (7.70e-3)" "potential prognostic favorable (3.09e-6)" "unprognostic (2.15e-1)" "unprognostic (8.05e-2)" "potential prognostic unfavorable (3.43e-5)" "unprognostic (4.18e-3)" "unprognostic (7.28e-3)" "unprognostic (7.33e-2)" "unprognostic (2.95e-1)" "unprognostic (1.56e-1)" "unprognostic (1.56e-1)" "unprognostic (5.40e-2)" "unprognostic (1.62e-1)" "unprognostic (6.47e-2)" "unprognostic (1.76e-2)" "unprognostic (7.08e-2)" "unprognostic (6.31e-2)" "unprognostic (1.35e-2)" "unprognostic (1.83e-1)" "unprognostic (1.48e-1)" "unprognostic (3.02e-2)" "unprognostic (8.17e-2)" COMMD9 "FLJ31106, HSPC166" ENSG00000110442 "COMM domain containing 9" Q9P000 11 36269284-36289449 "Predicted intracellular proteins" "Ion transport, Sodium transport, Transcription, Transcription regulation, Transport, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal suprabasal cells: 91.8;Hofbauer cells: 111.3;Oocytes: 128.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Lung - Macrophages, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009142 Uncertain Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 42 Nucleoplasm "Golgi apparatus, Cytosol" "HPA009142: " "unprognostic (4.56e-2)" "unprognostic (7.24e-2)" "unprognostic (1.93e-3)" "unprognostic (9.42e-2)" "unprognostic (7.36e-3)" "unprognostic (1.23e-1)" "unprognostic (1.91e-1)" "unprognostic (4.04e-1)" "unprognostic (5.08e-2)" "unprognostic (1.65e-2)" "potential prognostic favorable (2.49e-10)" "unprognostic (1.62e-2)" "potential prognostic favorable (1.82e-4)" "potential prognostic unfavorable (1.97e-5)" "unprognostic (9.50e-3)" "unprognostic (5.01e-2)" "unprognostic (3.49e-3)" "unprognostic (5.39e-2)" "unprognostic (5.78e-2)" "unprognostic (3.84e-2)" "unprognostic (4.95e-2)" "unprognostic (2.94e-1)" "unprognostic (5.43e-2)" "unprognostic (2.56e-1)" "unprognostic (9.86e-2)" "unprognostic (6.61e-2)" "unprognostic (1.10e-1)" "unprognostic (2.61e-1)" "unprognostic (1.63e-1)" "unprognostic (2.47e-1)" "unprognostic (1.30e-2)" COMP "EDM1, EPD1, MED, PSACH, THBS5" ENSG00000105664 "Cartilage oligomeric matrix protein" P49747 19 18782773-18791305 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Cell adhesion" Heparin-binding "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "blood vessel: 333.9" "Cell type enhanced" "Detected in some" "Early spermatids: 35.2;Endometrial glandular cells: 61.6;Epididymal basal cells: 205.9;Epididymal principal cells: 21.2;Fibroblasts: 76.4;Late primary spermatocytes: 56.7;Late spermatids: 148.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Pancreatic Adenocarcinoma (TCGA): 109.9" "Region enhanced" "Detected in single" "cerebellum: 2.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Bladder cancer: 6.7;Gastric cancer: 4.2;ovarian cancer: 12.3;Rhabdoid: 5.1" "Spleen - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" HPA077555 Approved "Golgi apparatus" "Secreted to extracellular matrix" "Cell adhesion" NA NA 1400000000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 35: Non-specific - DNA binding" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 7 "Golgi apparatus" "HPA077555: " "unprognostic (2.18e-3)" "unprognostic (1.31e-1)" "unprognostic (1.98e-1)" "unprognostic (1.11e-1)" "unprognostic (1.62e-3)" "unprognostic (7.62e-2)" "unprognostic (6.29e-2)" "unprognostic (1.30e-2)" "unprognostic (3.35e-1)" "unprognostic (4.74e-3)" "unprognostic (3.05e-2)" "unprognostic (2.62e-1)" "unprognostic (1.22e-2)" "unprognostic (6.06e-2)" "unprognostic (6.09e-2)" "unprognostic (4.88e-2)" "unprognostic (1.31e-2)" "potential prognostic unfavorable (3.41e-4)" "unprognostic (1.08e-2)" "unprognostic (2.23e-1)" "unprognostic (1.46e-1)" "unprognostic (2.77e-2)" "unprognostic (1.52e-2)" "unprognostic (1.85e-2)" "unprognostic (4.96e-3)" "unprognostic (1.16e-1)" "unprognostic (1.85e-2)" "unprognostic (8.00e-2)" COMT ENSG00000093010 Catechol-O-methyltransferase P21964 22 19941371-19969975 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Catecholamine metabolism, Lipid metabolism, Neurotransmitter degradation" "Methyltransferase, Transferase" "FDA approved drug targets, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 1150.1;Esophageal basal cells: 599.6;Esophageal suprabasal cells: 668.0;Syncytiotrophoblasts: 721.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001169, CAB011233" Enhanced Enhanced "Endoplasmic reticulum,Vesicles" NA NA 8200 "Cluster 2: Dendritic cells - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 62 Vesicles "Endoplasmic reticulum" "CAB011233: , HPA001169: " "unprognostic (2.62e-1)" "unprognostic (4.04e-2)" "unprognostic (2.68e-1)" "unprognostic (1.67e-1)" "unprognostic (1.06e-1)" "unprognostic (6.81e-2)" "unprognostic (9.85e-2)" "unprognostic (3.77e-2)" "unprognostic (8.65e-3)" "unprognostic (8.37e-2)" "unprognostic (3.21e-2)" "unprognostic (8.07e-2)" "unprognostic (8.59e-2)" "unprognostic (7.46e-2)" "unprognostic (3.92e-2)" "unprognostic (7.29e-3)" "unprognostic (2.52e-1)" "unprognostic (3.53e-1)" "unprognostic (4.07e-1)" "unprognostic (1.24e-1)" "unprognostic (2.77e-2)" "unprognostic (7.39e-3)" "unprognostic (9.19e-2)" "unprognostic (1.23e-2)" "unprognostic (1.04e-1)" "unprognostic (1.02e-1)" "unprognostic (5.83e-2)" "unprognostic (5.78e-2)" "unprognostic (9.93e-3)" "unprognostic (9.36e-2)" "unprognostic (1.59e-1)" COMTD1 FLJ23841 ENSG00000165644 "Catechol-O-methyltransferase domain containing 1" Q86VU5 10 75233641-75236030 "Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 96.9" "Cell type enhanced" "Detected in many" "Colonocytes: 252.3;Enterocytes: 391.1;Esophageal apical cells: 615.0;Esophageal basal cells: 379.4;Esophageal suprabasal cells: 465.6;Goblet cells: 176.2;Pancreatic acinar cells: 232.3" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 38.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042165 Approved Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 70: Non-specific - Protein processing" "Cluster 44: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 110 "Golgi apparatus" "Plasma membrane, Cytosol" "HPA042165: " "unprognostic (1.54e-1)" "potential prognostic unfavorable (6.78e-4)" "unprognostic (6.27e-2)" "unprognostic (6.04e-2)" "unprognostic (2.66e-1)" "unprognostic (1.84e-1)" "unprognostic (6.82e-2)" "unprognostic (1.95e-2)" "unprognostic (1.02e-1)" "unprognostic (1.03e-3)" "unprognostic (3.17e-1)" "unprognostic (3.25e-2)" "unprognostic (9.91e-2)" "unprognostic (1.22e-1)" "unprognostic (1.50e-3)" "unprognostic (1.54e-2)" "unprognostic (5.82e-2)" "unprognostic (1.16e-2)" "unprognostic (1.04e-2)" "unprognostic (3.23e-2)" "unprognostic (1.39e-1)" "unprognostic (2.61e-1)" "unprognostic (3.88e-1)" "unprognostic (6.41e-2)" "unprognostic (5.36e-3)" "unprognostic (4.24e-2)" "unprognostic (3.74e-1)" "unprognostic (2.73e-2)" "unprognostic (1.06e-1)" COP1 "CFAP78, FAP78, FLJ10416, RFWD2, RNF200" ENSG00000143207 "COP1 E3 ubiquitin ligase" Q8NHY2 1 175944831-176207286 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Neutrophil progenitors: 1335.9;Neutrophils: 2757.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 49: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 24: Neutrophils - Innate immunity signal integration" 69 "unprognostic (4.17e-3)" "unprognostic (2.21e-3)" "unprognostic (1.07e-1)" "unprognostic (8.92e-3)" "unprognostic (6.44e-3)" "unprognostic (2.39e-1)" "potential prognostic favorable (6.16e-4)" "unprognostic (7.08e-2)" "unprognostic (9.25e-2)" "potential prognostic favorable (7.72e-4)" "unprognostic (4.95e-2)" "unprognostic (1.07e-2)" "unprognostic (5.35e-2)" "unprognostic (2.72e-1)" "unprognostic (2.58e-1)" "unprognostic (6.85e-2)" "unprognostic (9.70e-2)" "unprognostic (9.75e-2)" "unprognostic (1.47e-2)" "unprognostic (2.96e-2)" "unprognostic (3.10e-2)" "unprognostic (4.37e-2)" "unprognostic (5.91e-2)" "unprognostic (4.72e-2)" "unprognostic (7.87e-3)" "unprognostic (2.32e-1)" "unprognostic (1.69e-1)" "unprognostic (2.15e-2)" "unprognostic (3.76e-1)" COPA HEP-COP ENSG00000122218 "COPI coat complex subunit alpha" P53621 1 160288594-160343566 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "ER-Golgi transport, Protein transport, Transport" Hormone "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 516.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028024 Supported Approved "Nucleoplasm,Golgi apparatus,Cytosol" "Secreted to blood" Hormone NA NA 170000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 134 "Nucleoplasm, Cytosol" "Golgi apparatus" "HPA028024: " "unprognostic (6.84e-2)" "unprognostic (4.07e-3)" "unprognostic (3.86e-1)" "unprognostic (9.59e-3)" "unprognostic (2.87e-2)" "unprognostic (2.02e-1)" "unprognostic (2.37e-1)" "unprognostic (2.85e-2)" "unprognostic (2.15e-2)" "unprognostic (1.06e-2)" "unprognostic (3.23e-3)" "unprognostic (1.86e-1)" "unprognostic (2.45e-3)" "potential prognostic unfavorable (7.07e-7)" "unprognostic (2.19e-2)" "unprognostic (1.08e-1)" "unprognostic (1.72e-3)" "unprognostic (1.83e-1)" "unprognostic (6.11e-2)" "unprognostic (1.00e-1)" "potential prognostic unfavorable (1.90e-4)" "unprognostic (2.13e-1)" "unprognostic (5.09e-2)" "unprognostic (2.49e-1)" "unprognostic (6.92e-2)" "unprognostic (4.22e-2)" "unprognostic (1.04e-1)" "unprognostic (6.25e-2)" "unprognostic (1.40e-1)" "unprognostic (5.59e-2)" "unprognostic (1.43e-1)" COPB1 COPB ENSG00000129083 "COPI coat complex subunit beta 1" P53618 11 14443440-14500027 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Host-virus interaction, Protein transport, Transport" "Cataract, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012338, HPA043954, HPA064403" Supported Enhanced "Golgi apparatus,Vesicles,Cytosol" NA NA 340000 "Cluster 33: Non-specific - ATP binding" "Cluster 22: Epididymis - Mixed function" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 24: Non-specific - Unknown function" "Cluster 8: Non-specific - Secretory pathway" 72 "Golgi apparatus, Vesicles, Cytosol" "CAB012338: , HPA043954: , HPA064403: " "unprognostic (5.17e-2)" "unprognostic (5.63e-2)" "unprognostic (1.41e-1)" "potential prognostic unfavorable (9.95e-4)" "unprognostic (1.09e-1)" "unprognostic (1.01e-2)" "unprognostic (1.88e-1)" "unprognostic (2.42e-2)" "unprognostic (1.84e-2)" "unprognostic (7.24e-2)" "potential prognostic favorable (5.26e-8)" "unprognostic (1.76e-2)" "unprognostic (1.21e-1)" "potential prognostic unfavorable (9.78e-6)" "unprognostic (1.78e-1)" "unprognostic (1.23e-1)" "unprognostic (4.42e-3)" "unprognostic (1.04e-2)" "unprognostic (4.86e-2)" "unprognostic (1.95e-1)" "potential prognostic unfavorable (7.58e-4)" "unprognostic (4.26e-3)" "unprognostic (8.74e-2)" "unprognostic (1.03e-1)" "unprognostic (1.60e-2)" "unprognostic (2.08e-1)" "unprognostic (6.42e-2)" "unprognostic (4.76e-2)" "unprognostic (1.73e-1)" "unprognostic (3.41e-1)" "unprognostic (1.43e-1)" COPB2 "beta'-COP, betaprime-COP" ENSG00000184432 "COPI coat complex subunit beta 2" P35606 3 139353946-139389736 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Osteoporosis, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036867, HPA058180" Approved Approved "Endoplasmic reticulum,Golgi apparatus" NA NA 110000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 70: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 8: Non-specific - Secretory pathway" 169 "Endoplasmic reticulum" "Golgi apparatus" "HPA036867: , HPA058180: " "unprognostic (3.79e-1)" "unprognostic (2.78e-3)" "unprognostic (4.51e-2)" "unprognostic (9.16e-3)" "unprognostic (8.59e-2)" "unprognostic (4.61e-2)" "unprognostic (2.71e-1)" "unprognostic (4.66e-3)" "unprognostic (1.15e-1)" "unprognostic (2.97e-3)" "potential prognostic favorable (3.58e-4)" "unprognostic (1.21e-1)" "unprognostic (1.85e-1)" "potential prognostic unfavorable (5.56e-5)" "unprognostic (1.43e-2)" "unprognostic (2.61e-2)" "unprognostic (4.45e-3)" "unprognostic (1.30e-1)" "unprognostic (4.05e-1)" "unprognostic (6.91e-2)" "unprognostic (7.95e-3)" "unprognostic (4.96e-3)" "unprognostic (1.58e-1)" "unprognostic (1.65e-1)" "unprognostic (5.11e-2)" "unprognostic (1.47e-2)" "unprognostic (2.30e-1)" "unprognostic (2.01e-1)" "unprognostic (1.30e-1)" "unprognostic (6.96e-2)" "unprognostic (2.45e-1)" COPE epsilon-COP ENSG00000105669 "COPI coat complex subunit epsilon" O14579 19 18899514-18919387 "Essential proteins, Metabolic proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 1002.6;Oocytes: 810.5;Syncytiotrophoblasts: 668.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034345, HPA041605, HPA043576" Supported Enhanced "Golgi apparatus" NA NA 82000 "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 8: Non-specific - Secretory pathway" 155 "Golgi apparatus" "CAB034345: , HPA041605: , HPA043576: " "unprognostic (1.46e-1)" "unprognostic (2.91e-1)" "unprognostic (3.56e-1)" "unprognostic (2.25e-2)" "unprognostic (2.69e-1)" "unprognostic (4.86e-2)" "unprognostic (1.51e-1)" "unprognostic (2.79e-1)" "unprognostic (2.59e-2)" "unprognostic (9.32e-2)" "unprognostic (1.70e-1)" "unprognostic (5.37e-2)" "unprognostic (1.30e-2)" "unprognostic (1.92e-3)" "potential prognostic unfavorable (3.85e-4)" "unprognostic (1.78e-1)" "unprognostic (2.76e-1)" "unprognostic (1.28e-1)" "unprognostic (2.23e-1)" "unprognostic (2.34e-1)" "unprognostic (2.57e-1)" "unprognostic (5.01e-3)" "unprognostic (3.30e-1)" "unprognostic (2.14e-1)" "unprognostic (1.06e-1)" "unprognostic (4.52e-2)" "unprognostic (2.28e-1)" "unprognostic (2.35e-1)" "unprognostic (1.47e-1)" "unprognostic (6.44e-2)" "potential prognostic favorable (4.77e-4)" COPG1 COPG ENSG00000181789 "COPI coat complex subunit gamma 1" Q9Y678 3 129249606-129277773 "Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037866, HPA037867, HPA045712" Supported Supported "Nucleoplasm,Golgi apparatus,Cytosol" No No 150000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 70: Non-specific - Protein processing" "Cluster 27: Non-specific - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 8: Non-specific - Secretory pathway" 77 "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA037866: , HPA037867: , HPA045712: " "unprognostic (1.63e-1)" "unprognostic (4.09e-2)" "unprognostic (2.74e-1)" "unprognostic (6.62e-2)" "unprognostic (6.65e-3)" "unprognostic (3.11e-1)" "unprognostic (2.82e-1)" "unprognostic (6.18e-3)" "unprognostic (3.35e-3)" "validated prognostic unfavorable (5.03e-4)" "validated prognostic unfavorable (6.79e-4)" "unprognostic (1.32e-1)" "potential prognostic unfavorable (1.20e-6)" "unprognostic (1.11e-2)" "unprognostic (8.53e-3)" "unprognostic (2.36e-1)" "unprognostic (4.66e-1)" "unprognostic (1.72e-1)" "unprognostic (1.96e-1)" "unprognostic (1.04e-2)" "unprognostic (6.22e-2)" "unprognostic (1.98e-1)" "unprognostic (1.69e-1)" "unprognostic (1.21e-1)" "unprognostic (2.30e-1)" "unprognostic (3.07e-1)" "unprognostic (1.95e-1)" "unprognostic (1.65e-1)" "unprognostic (2.74e-1)" COPG2 2-COP ENSG00000158623 "COPI coat complex subunit gamma 2" Q9UBF2 7 130506238-130668748 "Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 859.5;Epicardial cells: 277.4;Thyrotrophs: 194.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045712 Approved NA NA 26000 "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 39: Non-specific - Transcription" "Cluster 89: Adipocytes - Lipid metabolism" 59 "HPA045712: " "unprognostic (7.33e-2)" "unprognostic (1.67e-1)" "unprognostic (2.05e-2)" "potential prognostic unfavorable (5.86e-4)" "unprognostic (7.19e-2)" "unprognostic (1.57e-1)" "unprognostic (1.23e-1)" "unprognostic (7.79e-2)" "unprognostic (3.83e-1)" "unprognostic (1.62e-2)" "unprognostic (6.93e-2)" "unprognostic (4.40e-2)" "unprognostic (2.18e-2)" "unprognostic (1.17e-3)" "potential prognostic unfavorable (2.85e-4)" "unprognostic (2.45e-1)" "unprognostic (4.28e-1)" "unprognostic (4.06e-2)" "unprognostic (1.96e-1)" "unprognostic (1.36e-1)" "unprognostic (2.64e-1)" "unprognostic (3.83e-2)" "unprognostic (3.90e-1)" "unprognostic (3.00e-2)" "unprognostic (4.18e-2)" "unprognostic (3.01e-1)" "unprognostic (1.19e-1)" "unprognostic (2.06e-1)" "unprognostic (5.54e-1)" "unprognostic (1.71e-1)" "unprognostic (2.71e-2)" COPRS "C17orf79, COPR5, HSA272196, TTP1" ENSG00000172301 "Coordinator of PRMT5 and differentiation stimulator" Q9NQ92 17 31851871-31859291 "Predicted intracellular proteins" "Myogenesis, Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal clear cells: 230.7;Epididymal efferent duct ciliated cells: 330.7;Epididymal principal cells: 251.6;Fallopian tube ciliated cells: 289.4;Late primary spermatocytes: 981.8;Late spermatids: 421.7;Respiratory ciliated cells: 229.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052552 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 14: Neurons - Synaptic function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 32 Nucleoplasm "Plasma membrane, Cytosol" "HPA052552: " "unprognostic (3.37e-3)" "unprognostic (2.17e-1)" "unprognostic (9.64e-2)" "unprognostic (1.72e-1)" "unprognostic (5.78e-2)" "potential prognostic unfavorable (2.79e-4)" "unprognostic (2.81e-1)" "unprognostic (6.55e-3)" "unprognostic (1.09e-2)" "unprognostic (8.05e-3)" "unprognostic (1.30e-1)" "unprognostic (1.46e-2)" "potential prognostic unfavorable (6.68e-5)" "unprognostic (6.07e-3)" "unprognostic (4.35e-2)" "unprognostic (3.51e-1)" "unprognostic (1.80e-1)" "unprognostic (1.04e-1)" "unprognostic (4.53e-2)" "unprognostic (4.91e-3)" "unprognostic (2.37e-1)" "unprognostic (2.86e-2)" "unprognostic (2.45e-2)" "unprognostic (1.62e-2)" "unprognostic (9.10e-2)" "unprognostic (7.96e-3)" "unprognostic (1.39e-1)" "unprognostic (4.32e-1)" "unprognostic (8.17e-2)" COPS2 "ALIEN, CSN2, TRIP15" ENSG00000166200 "COP9 signalosome subunit 2" P61201 15 49106068-49155661 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016867, HPA018271, HPA061071" Approved Supported "Vesicles,Cytokinetic bridge" Yes No 250000 "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 80 Vesicles "Cytokinetic bridge" "HPA016867: , HPA018271: , HPA061071: " "unprognostic (1.93e-1)" "unprognostic (1.07e-1)" "unprognostic (2.49e-1)" "unprognostic (1.59e-2)" "unprognostic (2.62e-1)" "unprognostic (9.94e-2)" "unprognostic (3.55e-1)" "unprognostic (2.37e-1)" "unprognostic (4.10e-3)" "unprognostic (3.36e-3)" "validated prognostic favorable (8.53e-8)" "validated prognostic favorable (4.81e-5)" "unprognostic (1.79e-2)" "unprognostic (6.18e-2)" "unprognostic (4.99e-3)" "unprognostic (3.36e-3)" "unprognostic (4.21e-3)" "unprognostic (2.47e-1)" "unprognostic (2.38e-1)" "unprognostic (7.50e-2)" "unprognostic (4.13e-2)" "potential prognostic unfavorable (4.35e-4)" "unprognostic (1.38e-2)" "unprognostic (7.95e-2)" "unprognostic (9.99e-2)" "unprognostic (2.38e-1)" "unprognostic (9.67e-2)" "unprognostic (2.27e-1)" "unprognostic (1.59e-1)" "unprognostic (3.93e-2)" "unprognostic (6.04e-2)" COPS3 "CSN3, SGN3" ENSG00000141030 "COP9 signalosome subunit 3" Q9UNS2 17 17246616-17281273 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 359.6;Oocytes: 221.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021997, HPA050557" Approved Supported Nucleoplasm,Cytosol NA NA 95000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 42: Non-specific - Unknown function" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 138 "Nucleoplasm, Cytosol" "HPA021997: , HPA050557: " "unprognostic (3.14e-3)" "unprognostic (1.30e-2)" "unprognostic (3.00e-3)" "unprognostic (2.76e-1)" "unprognostic (1.31e-1)" "unprognostic (7.18e-2)" "unprognostic (1.19e-1)" "unprognostic (1.76e-1)" "unprognostic (2.11e-1)" "unprognostic (2.02e-3)" "unprognostic (2.68e-3)" "unprognostic (2.72e-1)" "unprognostic (1.40e-1)" "unprognostic (1.53e-3)" "unprognostic (5.59e-2)" "unprognostic (2.04e-3)" "unprognostic (1.90e-1)" "unprognostic (1.89e-1)" "unprognostic (2.39e-1)" "unprognostic (1.54e-1)" "unprognostic (2.41e-2)" "unprognostic (5.02e-2)" "unprognostic (1.14e-1)" "unprognostic (3.13e-3)" "unprognostic (8.91e-2)" "unprognostic (1.69e-1)" "unprognostic (7.16e-2)" "unprognostic (1.43e-1)" "unprognostic (2.57e-1)" "unprognostic (3.88e-2)" "unprognostic (1.93e-1)" COPS4 "CSN4, SGN4" ENSG00000138663 "COP9 signalosome subunit 4" Q9BT78 4 83034447-83075818 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 272.2;Oocytes: 184.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036894, HPA042828" Approved Supported "Nuclear speckles" NA NA 260000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 86 "Nuclear speckles" "HPA036894: , HPA042828: " "unprognostic (3.23e-1)" "potential prognostic unfavorable (1.12e-5)" "unprognostic (5.32e-3)" "unprognostic (3.07e-1)" "potential prognostic favorable (3.77e-4)" "unprognostic (2.57e-1)" "unprognostic (1.50e-1)" "unprognostic (5.44e-2)" "unprognostic (1.96e-1)" "unprognostic (1.62e-1)" "validated prognostic favorable (3.01e-9)" "validated prognostic favorable (9.64e-6)" "unprognostic (7.70e-3)" "potential prognostic unfavorable (2.74e-4)" "unprognostic (1.75e-1)" "unprognostic (5.02e-2)" "unprognostic (4.72e-1)" "unprognostic (2.49e-1)" "unprognostic (2.02e-2)" "unprognostic (1.54e-1)" "unprognostic (6.81e-3)" "unprognostic (1.65e-1)" "unprognostic (9.19e-2)" "unprognostic (4.85e-2)" "unprognostic (1.56e-3)" "unprognostic (2.49e-1)" "unprognostic (4.40e-1)" "unprognostic (5.93e-2)" "unprognostic (2.53e-1)" "unprognostic (2.15e-1)" "unprognostic (1.81e-2)" COPS5 "CSN5, JAB1, MOV-34, SGN5" ENSG00000121022 "COP9 signalosome subunit 5" Q92905 8 67043079-67083783 "Enzymes, Essential proteins, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 453.3;Late primary spermatocytes: 387.5;Late spermatids: 757.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004242, HPA004845, HPA051531" Supported Enhanced Nucleoplasm NA NA 35000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 52: Non-specific - Cellular respiration" "Cluster 27: Non-specific - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 241 Nucleoplasm "CAB004242: , HPA004845: , HPA051531: " "unprognostic (2.16e-1)" "potential prognostic unfavorable (4.36e-5)" "unprognostic (1.56e-1)" "unprognostic (1.70e-1)" "unprognostic (2.73e-1)" "unprognostic (1.58e-1)" "unprognostic (6.03e-2)" "potential prognostic favorable (1.30e-4)" "unprognostic (6.37e-3)" "potential prognostic unfavorable (9.76e-4)" "potential prognostic favorable (4.16e-5)" "unprognostic (9.52e-2)" "unprognostic (7.73e-2)" "potential prognostic unfavorable (7.64e-4)" "unprognostic (2.78e-2)" "potential prognostic unfavorable (1.95e-4)" "unprognostic (1.07e-1)" "unprognostic (3.55e-2)" "unprognostic (2.69e-1)" "unprognostic (1.82e-1)" "unprognostic (6.58e-3)" "unprognostic (5.18e-3)" "unprognostic (3.61e-3)" "unprognostic (4.23e-2)" "unprognostic (6.15e-3)" "unprognostic (9.11e-2)" "unprognostic (5.07e-2)" "unprognostic (1.06e-1)" "unprognostic (1.49e-1)" "unprognostic (2.20e-1)" "unprognostic (6.11e-2)" COPS6 "CSN6, MOV34-34KD" ENSG00000168090 "COP9 signalosome subunit 6" Q7L5N1 7 100088969-100092187 "Enzymes, Essential proteins, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 309.6;Esophageal apical cells: 380.2;Esophageal suprabasal cells: 345.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044315 Approved Supported Nucleoplasm NA NA 72000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 39: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 156 Nucleoplasm "HPA044315: " "unprognostic (2.26e-1)" "unprognostic (4.17e-2)" "unprognostic (1.56e-1)" "unprognostic (3.94e-2)" "unprognostic (1.53e-1)" "unprognostic (2.49e-2)" "unprognostic (3.16e-2)" "unprognostic (5.65e-3)" "unprognostic (1.66e-3)" "potential prognostic unfavorable (8.21e-6)" "potential prognostic favorable (3.60e-4)" "unprognostic (6.67e-3)" "unprognostic (2.95e-1)" "validated prognostic unfavorable (5.70e-5)" "validated prognostic unfavorable (3.05e-7)" "potential prognostic unfavorable (5.40e-4)" "unprognostic (9.08e-3)" "unprognostic (6.54e-2)" "unprognostic (4.53e-1)" "unprognostic (1.24e-1)" "unprognostic (2.48e-1)" "unprognostic (1.55e-1)" "unprognostic (2.48e-2)" "unprognostic (1.53e-1)" "unprognostic (7.56e-2)" "unprognostic (2.15e-1)" "unprognostic (3.05e-1)" "unprognostic (9.96e-2)" "unprognostic (9.85e-2)" "unprognostic (3.79e-2)" "unprognostic (1.29e-1)" COPS7A CSN7A ENSG00000111652 "COP9 signalosome subunit 7A" Q9UBW8 12 6724014-6731875 "Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Spleen - Fibroblasts_1, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026915 Supported Supported Nucleoplasm,Cytosol NA NA 69000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 38: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 70 Nucleoplasm Cytosol "HPA026915: " "unprognostic (5.01e-2)" "unprognostic (1.14e-1)" "unprognostic (1.42e-1)" "unprognostic (2.21e-2)" "unprognostic (9.93e-3)" "potential prognostic unfavorable (1.55e-4)" "unprognostic (8.28e-2)" "unprognostic (4.32e-1)" "unprognostic (5.10e-3)" "unprognostic (4.16e-2)" "unprognostic (7.55e-2)" "unprognostic (3.33e-2)" "unprognostic (4.17e-3)" "unprognostic (3.89e-2)" "unprognostic (1.07e-3)" "unprognostic (2.85e-2)" "unprognostic (6.84e-2)" "unprognostic (1.43e-2)" "unprognostic (1.98e-2)" "unprognostic (6.56e-3)" "unprognostic (2.67e-1)" "unprognostic (5.07e-1)" "unprognostic (1.69e-2)" "unprognostic (8.64e-2)" "unprognostic (9.28e-2)" "unprognostic (7.31e-2)" "unprognostic (6.18e-2)" "unprognostic (2.28e-1)" "unprognostic (2.75e-1)" "unprognostic (2.12e-1)" "unprognostic (4.56e-2)" COPS7B CSN7B ENSG00000144524 "COP9 signalosome subunit 7B" Q9H9Q2 2 231781671-231809254 "Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 276.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034675, HPA034676" Uncertain Supported Nucleoplasm NA NA 47000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 39: Testis - Nuclear processes" "Cluster 34: Non-specific - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 41: Oocytes - Oogenesis" 75 Nucleoplasm "HPA034675: , HPA034676: " "unprognostic (1.89e-1)" "unprognostic (6.06e-2)" "unprognostic (1.20e-1)" "unprognostic (1.69e-2)" "unprognostic (6.32e-3)" "unprognostic (1.53e-1)" "unprognostic (1.34e-1)" "unprognostic (7.80e-2)" "unprognostic (1.44e-1)" "unprognostic (7.91e-2)" "unprognostic (1.40e-1)" "unprognostic (1.62e-1)" "unprognostic (2.06e-1)" "potential prognostic unfavorable (2.76e-5)" "unprognostic (9.05e-3)" "unprognostic (1.57e-1)" "unprognostic (9.65e-3)" "unprognostic (2.86e-1)" "unprognostic (1.28e-2)" "unprognostic (1.54e-1)" "unprognostic (3.75e-1)" "unprognostic (8.48e-2)" "unprognostic (3.23e-3)" "unprognostic (1.28e-3)" "unprognostic (1.67e-1)" "potential prognostic favorable (3.91e-4)" "unprognostic (2.74e-2)" "unprognostic (3.59e-2)" "unprognostic (2.59e-1)" "unprognostic (3.62e-1)" "unprognostic (1.59e-1)" COPS8 "COP9, CSN8, MGC1297, SGN8" ENSG00000198612 "COP9 signalosome subunit 8" Q99627 2 237085882-237100474 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Oocytes: 1109.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036485 Uncertain Supported Nucleoplasm,Cytosol NA NA 190000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 82 Nucleoplasm Cytosol "HPA036485: " "unprognostic (3.65e-1)" "unprognostic (9.17e-3)" "unprognostic (5.27e-3)" "unprognostic (2.63e-1)" "unprognostic (1.56e-1)" "unprognostic (1.97e-1)" "unprognostic (2.18e-1)" "potential prognostic unfavorable (9.83e-4)" "unprognostic (3.45e-3)" "unprognostic (4.59e-3)" "potential prognostic favorable (2.15e-8)" "unprognostic (7.64e-2)" "unprognostic (1.12e-1)" "validated prognostic unfavorable (5.56e-5)" "validated prognostic unfavorable (1.27e-4)" "potential prognostic unfavorable (8.13e-4)" "unprognostic (1.60e-2)" "unprognostic (3.29e-2)" "unprognostic (1.56e-1)" "unprognostic (4.56e-2)" "unprognostic (1.59e-1)" "unprognostic (7.11e-2)" "unprognostic (4.06e-2)" "unprognostic (1.35e-1)" "unprognostic (2.63e-2)" "unprognostic (1.74e-2)" "unprognostic (4.25e-1)" "unprognostic (1.82e-2)" "unprognostic (9.89e-2)" "unprognostic (6.95e-2)" "unprognostic (1.92e-1)" COPS9 "CSNAP, MYEOV2" ENSG00000172428 "COP9 signalosome subunit 9" Q8WXC6 2 240126563-240136807 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 846.1;Esophageal apical cells: 706.8;Esophageal suprabasal cells: 755.4;Parietal cells: 645.3" "Cell type enhanced" "Detected in all" "hippocampal CA4: 179.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skin - Inner root sheath cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" HPA044845 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 27: Non-specific - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 97: Non-specific - Cellular respiration" 18 "Nucleoplasm, Cytosol" "HPA044845: " "unprognostic (7.31e-2)" "unprognostic (2.27e-2)" "unprognostic (3.19e-2)" "unprognostic (2.87e-1)" "potential prognostic favorable (8.44e-4)" "unprognostic (1.30e-1)" "unprognostic (7.56e-3)" "unprognostic (6.85e-2)" "potential prognostic unfavorable (2.92e-4)" "unprognostic (1.84e-1)" "unprognostic (5.58e-3)" "unprognostic (2.84e-1)" "potential prognostic unfavorable (5.94e-5)" "potential prognostic unfavorable (6.15e-4)" "unprognostic (2.50e-1)" "unprognostic (1.32e-1)" "unprognostic (1.16e-1)" "unprognostic (1.99e-1)" "unprognostic (3.14e-1)" "unprognostic (1.52e-2)" "unprognostic (5.07e-3)" "unprognostic (1.00e-1)" "unprognostic (9.04e-2)" "unprognostic (3.15e-2)" "unprognostic (4.31e-2)" "unprognostic (3.48e-2)" "unprognostic (8.45e-3)" "unprognostic (3.47e-1)" "unprognostic (1.35e-1)" COPZ1 "CGI-120, COPZ" ENSG00000111481 "COPI coat complex subunit zeta 1" P61923 12 54301202-54351846 "Essential proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 545.2;Esophageal suprabasal cells: 310.5;Extravillous trophoblasts: 352.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Prostate - Prostate glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 330000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 38: Non-specific - Transcription" "Cluster 8: Non-specific - Secretory pathway" 70 "unprognostic (9.46e-2)" "unprognostic (8.95e-3)" "unprognostic (4.70e-2)" "unprognostic (1.99e-2)" "unprognostic (2.93e-1)" "unprognostic (1.35e-1)" "unprognostic (2.76e-1)" "unprognostic (4.01e-1)" "unprognostic (2.43e-3)" "unprognostic (2.22e-3)" "unprognostic (4.71e-2)" "unprognostic (6.24e-3)" "unprognostic (7.85e-3)" "validated prognostic unfavorable (2.04e-7)" "validated prognostic unfavorable (3.85e-7)" "potential prognostic unfavorable (4.09e-5)" "unprognostic (3.14e-2)" "unprognostic (7.35e-2)" "unprognostic (1.31e-1)" "unprognostic (1.95e-2)" "unprognostic (4.35e-2)" "unprognostic (8.68e-2)" "unprognostic (1.89e-1)" "unprognostic (1.94e-1)" "unprognostic (3.63e-1)" "unprognostic (9.25e-2)" "unprognostic (3.44e-3)" "unprognostic (3.28e-1)" "unprognostic (1.10e-1)" "unprognostic (1.47e-1)" "potential prognostic favorable (2.13e-4)" COPZ2 MGC23008 ENSG00000005243 "COPI coat complex subunit zeta 2" Q9P299 17 48026167-48038030 "Essential proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast lactating cells: 48.8;Breast myoepithelial cells: 60.3;Decidual stromal cells: 77.0;Endometrial stromal cells: 48.9;Fibroblasts: 66.9;Hepatic stellate cells: 109.7;Hepatocytes: 45.8;Leydig cells: 41.1;Peritubular myoid cells: 40.7;Smooth muscle cells: 51.8;Thymic myoid cells: 43.5;Vascular smooth muscle cells: 43.0" "Group enriched" "Detected in many" 4 "astrocyte: 9.9;Bergmann glia: 8.7;choroid plexus epithelial cell: 7.7;endothelial cell: 16.7;fibroblast: 26.4;pericyte: 11.2;vascular associated smooth muscle cell: 16.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Skin - Fibroblasts_1, Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055999 Uncertain NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 8: Immune cells - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 10 "HPA055999: " "unprognostic (9.33e-2)" "unprognostic (3.22e-1)" "unprognostic (3.86e-2)" "unprognostic (1.47e-1)" "unprognostic (5.75e-3)" "unprognostic (4.54e-2)" "unprognostic (5.16e-2)" "potential prognostic unfavorable (5.20e-4)" "unprognostic (2.74e-2)" "unprognostic (2.25e-1)" "unprognostic (2.42e-3)" "unprognostic (2.20e-2)" "unprognostic (1.87e-1)" "unprognostic (1.53e-1)" "unprognostic (1.36e-1)" "unprognostic (1.54e-2)" "unprognostic (1.81e-2)" "unprognostic (1.32e-1)" "unprognostic (1.16e-2)" "unprognostic (7.71e-2)" "unprognostic (1.32e-3)" "unprognostic (3.30e-2)" "unprognostic (3.36e-1)" "unprognostic (2.18e-2)" "unprognostic (6.48e-2)" "unprognostic (1.51e-2)" "unprognostic (1.28e-1)" "unprognostic (1.63e-3)" "unprognostic (1.11e-1)" "potential prognostic unfavorable (3.68e-5)" "unprognostic (3.88e-2)" COQ10A FLJ32452 ENSG00000135469 "Coenzyme Q10A" Q96MF6 12 56266890-56270966 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "heart muscle: 157.6;skeletal muscle: 263.1;tongue: 361.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 122.1;Myonuclei: 237.8;Retinal pigment epithelial cells: 51.2;Thymic myoid cells: 112.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068931 Approved "Endoplasmic reticulum,Golgi apparatus,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 19: Astrocytes - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" "Endoplasmic reticulum, Cytosol" "Golgi apparatus" "HPA068931: " "unprognostic (6.34e-2)" "unprognostic (6.22e-2)" "unprognostic (7.38e-2)" "unprognostic (4.63e-2)" "unprognostic (7.40e-2)" "unprognostic (9.59e-3)" "unprognostic (6.86e-2)" "unprognostic (6.59e-3)" "unprognostic (1.74e-1)" "unprognostic (5.49e-3)" "unprognostic (2.38e-2)" "unprognostic (2.70e-3)" "potential prognostic favorable (4.16e-6)" "unprognostic (1.64e-1)" "unprognostic (2.93e-2)" "unprognostic (8.02e-3)" "unprognostic (3.34e-1)" "unprognostic (1.74e-2)" "unprognostic (1.06e-2)" "unprognostic (1.51e-1)" "unprognostic (5.28e-2)" "potential prognostic favorable (2.95e-4)" "unprognostic (9.16e-2)" "unprognostic (4.22e-1)" "unprognostic (1.90e-1)" "unprognostic (2.01e-1)" "unprognostic (2.65e-2)" "unprognostic (2.40e-1)" "unprognostic (6.73e-2)" "unprognostic (2.81e-2)" "unprognostic (1.00e-1)" COQ10B FLJ13448 ENSG00000115520 "Coenzyme Q10B" Q9H8M1 2 197453493-197475310 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 257.3;Syncytiotrophoblasts: 277.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046057 Approved Approved Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 76: Non-specific - Metabolism" "Cluster 27: Non-specific - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 29: Neutrophils - Innate immune cellular maintenance" Cytosol "HPA046057: " "potential prognostic favorable (4.97e-4)" "unprognostic (2.60e-2)" "unprognostic (9.99e-2)" "unprognostic (1.44e-2)" "unprognostic (2.74e-1)" "unprognostic (2.98e-1)" "unprognostic (2.03e-3)" "unprognostic (1.08e-2)" "unprognostic (2.51e-2)" "unprognostic (8.50e-2)" "unprognostic (2.12e-3)" "unprognostic (2.28e-1)" "unprognostic (1.99e-1)" "unprognostic (1.82e-1)" "unprognostic (6.94e-2)" "unprognostic (1.71e-1)" "unprognostic (3.20e-1)" "unprognostic (5.55e-2)" "unprognostic (2.33e-1)" "unprognostic (3.07e-1)" "unprognostic (4.22e-2)" "unprognostic (1.90e-2)" "unprognostic (3.60e-2)" "unprognostic (1.02e-1)" "unprognostic (3.62e-2)" "unprognostic (8.14e-2)" "unprognostic (8.70e-2)" "unprognostic (2.00e-1)" "unprognostic (3.24e-1)" "unprognostic (1.91e-1)" "unprognostic (7.58e-2)" COQ2 "CL640, FLJ26072" ENSG00000173085 "Coenzyme Q2, polyprenyltransferase" Q96H96 4 83261536-83284914 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Isoprene biosynthesis, Ubiquinone biosynthesis" Transferase "Disease variant, Neurodegeneration, Parkinsonism, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 35.0" "Cell type enhanced" "Detected in many" "Hofbauer cells: 66.2;Kupffer cells: 148.6" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 42.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Skin - Keratinocyte (other), Spleen - Macrophages, Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056599, HPA068727" Approved Approved Cytosol NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 1 Cytosol "HPA056599: , HPA068727: " "unprognostic (9.99e-3)" "unprognostic (4.39e-2)" "unprognostic (1.84e-1)" "unprognostic (6.88e-2)" "potential prognostic favorable (8.83e-5)" "unprognostic (3.12e-2)" "unprognostic (7.86e-2)" "unprognostic (5.21e-2)" "unprognostic (1.29e-1)" "unprognostic (6.71e-2)" "unprognostic (6.71e-3)" "unprognostic (4.05e-3)" "unprognostic (2.40e-1)" "unprognostic (3.73e-2)" "unprognostic (2.23e-1)" "unprognostic (1.28e-3)" "unprognostic (1.32e-1)" "unprognostic (1.95e-1)" "unprognostic (6.11e-2)" "unprognostic (4.07e-1)" "unprognostic (2.53e-1)" "unprognostic (2.88e-2)" "unprognostic (2.19e-1)" "unprognostic (6.14e-2)" "unprognostic (3.18e-3)" "unprognostic (2.58e-2)" "unprognostic (2.83e-1)" "unprognostic (2.61e-1)" "unprognostic (2.08e-1)" "unprognostic (1.89e-1)" "unprognostic (7.99e-2)" COQ3 bA9819.1 ENSG00000132423 "Coenzyme Q3, methyltransferase" Q9NZJ6 6 99369401-99394195 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubiquinone biosynthesis" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 47.7" "Cell type enhanced" "Detected in many" "Myonuclei: 35.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031273, HPA031274" Enhanced Approved Nucleoplasm,Mitochondria NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 52: Non-specific - Cellular respiration" "Cluster 31: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 97: Non-specific - Cellular respiration" 14 Nucleoplasm Mitochondria "HPA031273: , HPA031274: " "unprognostic (5.92e-3)" "unprognostic (3.10e-3)" "unprognostic (1.63e-2)" "unprognostic (1.94e-2)" "unprognostic (8.49e-2)" "potential prognostic favorable (2.90e-4)" "unprognostic (7.37e-2)" "unprognostic (5.16e-2)" "unprognostic (4.69e-2)" "unprognostic (9.62e-3)" "unprognostic (3.25e-3)" "unprognostic (7.32e-3)" "unprognostic (1.31e-2)" "unprognostic (1.44e-3)" "unprognostic (2.61e-2)" "unprognostic (3.43e-3)" "unprognostic (9.81e-2)" "unprognostic (9.54e-3)" "unprognostic (5.68e-3)" "unprognostic (2.08e-1)" "unprognostic (1.06e-2)" "unprognostic (9.15e-2)" "unprognostic (1.13e-1)" "unprognostic (1.89e-1)" "unprognostic (1.36e-2)" "unprognostic (5.18e-2)" "unprognostic (1.25e-1)" "unprognostic (7.76e-2)" "unprognostic (9.13e-2)" "unprognostic (8.96e-2)" "unprognostic (2.13e-2)" COQ4 CGI-92 ENSG00000167113 "Coenzyme Q4" Q9Y3A0 9 128322544-128334072 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Ubiquinone biosynthesis" Lyase "Disease variant, Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Fallopian tube ciliated cells: 216.7;Respiratory ciliated cells: 213.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021406, HPA042945" Supported Supported Mitochondria NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 70: Non-specific - Protein processing" "Cluster 17: Choroid plexus - Cilium" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 107: Ciliated cells - Cilia assembly & function" 11 Mitochondria "HPA021406: , HPA042945: " "unprognostic (4.14e-2)" "unprognostic (3.46e-1)" "unprognostic (1.98e-1)" "potential prognostic favorable (1.30e-4)" "unprognostic (1.75e-1)" "unprognostic (4.82e-3)" "unprognostic (3.11e-1)" "unprognostic (8.48e-3)" "unprognostic (1.05e-1)" "unprognostic (4.37e-2)" "potential prognostic favorable (2.15e-5)" "unprognostic (1.78e-2)" "potential prognostic favorable (9.54e-10)" "unprognostic (1.58e-1)" "unprognostic (2.56e-2)" "unprognostic (1.57e-1)" "unprognostic (9.03e-2)" "unprognostic (3.41e-3)" "unprognostic (1.04e-2)" "unprognostic (3.24e-1)" "unprognostic (4.13e-3)" "unprognostic (2.88e-2)" "unprognostic (1.69e-1)" "unprognostic (2.27e-2)" "unprognostic (1.89e-1)" "unprognostic (1.09e-1)" "unprognostic (1.43e-1)" "unprognostic (6.28e-2)" "unprognostic (6.52e-3)" "unprognostic (1.20e-1)" "unprognostic (3.36e-2)" COQ5 MGC4767 ENSG00000110871 "Coenzyme Q5, methyltransferase" Q5HYK3 12 120503279-120534434 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubiquinone biosynthesis" "Methyltransferase, Transferase" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 89.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049487 Approved Approved Nucleoli,Mitochondria NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 11: White matter - Signal transduction" "Cluster 38: Non-specific - Transcription" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 25 "Nucleoli, Mitochondria" "HPA049487: " "unprognostic (7.83e-2)" "unprognostic (1.61e-2)" "potential prognostic unfavorable (3.72e-4)" "unprognostic (2.49e-1)" "unprognostic (6.05e-2)" "unprognostic (9.06e-2)" "unprognostic (1.70e-1)" "unprognostic (4.72e-2)" "unprognostic (5.21e-2)" "unprognostic (4.72e-3)" "validated prognostic favorable (1.07e-4)" "validated prognostic favorable (3.98e-4)" "unprognostic (1.97e-1)" "unprognostic (1.63e-1)" "unprognostic (6.35e-3)" "unprognostic (7.61e-3)" "unprognostic (1.91e-1)" "unprognostic (1.14e-1)" "unprognostic (6.45e-2)" "unprognostic (2.05e-1)" "potential prognostic unfavorable (6.92e-4)" "unprognostic (1.16e-1)" "unprognostic (7.68e-3)" "unprognostic (1.36e-1)" "unprognostic (7.55e-2)" "unprognostic (3.03e-1)" "unprognostic (1.93e-1)" "unprognostic (2.41e-1)" "unprognostic (1.60e-1)" "unprognostic (1.60e-1)" "unprognostic (5.69e-2)" COQ6 CGI-10 ENSG00000119723 "Coenzyme Q6, monooxygenase" Q9Y2Z9 14 73949926-73963670 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Ubiquinone biosynthesis" "Monooxygenase, Oxidoreductase" "Deafness, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 219.4;Late spermatids: 64.5;Myonuclei: 62.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051371 Uncertain NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 17 "HPA051371: " "unprognostic (7.21e-2)" "unprognostic (5.11e-2)" "unprognostic (7.73e-3)" "unprognostic (3.71e-1)" "unprognostic (1.14e-1)" "unprognostic (3.96e-1)" "unprognostic (2.77e-1)" "unprognostic (1.80e-2)" "unprognostic (9.72e-2)" "unprognostic (2.20e-1)" "potential prognostic favorable (5.16e-4)" "unprognostic (3.86e-2)" "potential prognostic favorable (4.24e-4)" "unprognostic (7.23e-2)" "unprognostic (2.93e-2)" "unprognostic (1.26e-2)" "unprognostic (7.75e-2)" "unprognostic (7.17e-2)" "unprognostic (9.30e-2)" "unprognostic (2.02e-1)" "unprognostic (2.85e-2)" "unprognostic (3.25e-2)" "unprognostic (9.34e-2)" "unprognostic (2.11e-1)" "unprognostic (5.79e-2)" "unprognostic (2.90e-1)" "unprognostic (2.27e-2)" "unprognostic (7.78e-2)" "unprognostic (2.74e-1)" "unprognostic (3.53e-3)" "unprognostic (3.05e-2)" COQ7 "CAT5, CLK-1" ENSG00000167186 "Coenzyme Q7, hydroxylase" Q99807 16 19067614-19080095 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ubiquinone biosynthesis" "Monooxygenase, Oxidoreductase" "Disease variant, Neurodegeneration, Neuropathy, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 167.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 40.4;neutrophil: 126.8" "Lineage enriched" "Detected in all" 8 "granulocytes: 126.8" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067252, HPA071922" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 3: Choroid plexus - Cilium" "Cluster 54: Non-specific - Transcription" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 7 "Plasma membrane" Nucleoplasm "HPA067252: , HPA071922: " "unprognostic (4.06e-1)" "unprognostic (7.63e-3)" "unprognostic (2.06e-1)" "unprognostic (5.00e-2)" "unprognostic (1.44e-1)" "unprognostic (2.72e-1)" "unprognostic (1.43e-2)" "unprognostic (2.23e-1)" "unprognostic (1.08e-1)" "unprognostic (6.45e-2)" "potential prognostic favorable (7.56e-10)" "unprognostic (1.81e-2)" "unprognostic (3.23e-3)" "unprognostic (3.11e-2)" "unprognostic (9.42e-2)" "unprognostic (1.03e-1)" "unprognostic (5.98e-2)" "unprognostic (2.79e-1)" "unprognostic (2.46e-1)" "unprognostic (4.30e-1)" "unprognostic (3.18e-2)" "unprognostic (4.57e-2)" "unprognostic (2.66e-2)" "unprognostic (1.10e-1)" "unprognostic (2.00e-2)" "unprognostic (3.05e-1)" "unprognostic (8.72e-2)" "unprognostic (4.29e-1)" "unprognostic (2.78e-1)" "unprognostic (1.97e-2)" "unprognostic (1.42e-1)" COQ8A "ADCK3, CABC1, COQ8, SCAR9" ENSG00000163050 "Coenzyme Q8A" Q8NI60 1 226940286-226987544 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Ubiquinone biosynthesis" "Kinase, Transferase" "Disease variant, Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "skeletal muscle: 1091.3;tongue: 452.9" "Cell type enhanced" "Detected in some" "Astrocytes: 20.6;Bergmann glia: 23.5;Brain excitatory neurons: 51.9;Brain inhibitory neurons: 39.6;Choroid plexus epithelial cells: 60.1;Distal convoluted tubule cells: 32.1;Ependymal cells: 17.7;Loop of henle epithelial cells: 29.5;Microglia: 22.8;Oligodendrocyte progenitor cells: 25.5;Oligodendrocytes: 26.9;Other brain neurons: 37.0;Papillary tip epithelial cells: 18.2;Proximal tubule cells: 39.5;Renal collecting duct intercalated cells: 31.5;Renal collecting duct principal cells: 24.3;Renal connecting tubule cells: 24.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061662 Supported Mitochondria NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 45: Non-specific - Nuclear processes" "Cluster 102: Non-specific - Mixed function" 44 Mitochondria "HPA061662: " "unprognostic (9.91e-2)" "unprognostic (8.15e-2)" "unprognostic (2.17e-1)" "unprognostic (9.84e-2)" "unprognostic (2.14e-1)" "unprognostic (6.98e-2)" "potential prognostic favorable (4.82e-4)" "unprognostic (1.80e-1)" "unprognostic (2.24e-1)" "potential prognostic favorable (2.60e-8)" "unprognostic (1.76e-2)" "unprognostic (2.09e-1)" "unprognostic (2.29e-2)" "unprognostic (1.58e-2)" "unprognostic (8.26e-2)" "unprognostic (5.36e-2)" "unprognostic (5.58e-2)" "unprognostic (1.02e-1)" "unprognostic (4.67e-2)" "unprognostic (2.44e-1)" "unprognostic (1.54e-2)" "unprognostic (1.14e-1)" "potential prognostic favorable (9.14e-4)" "unprognostic (1.19e-2)" "unprognostic (1.41e-1)" "unprognostic (1.68e-1)" "unprognostic (1.69e-1)" "unprognostic (1.49e-1)" "unprognostic (1.34e-2)" COQ8B "ADCK4, COQ8, FLJ12229" ENSG00000123815 "Coenzyme Q8B" Q96D53 19 40691514-40725784 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epicardial cells: 291.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027229, HPA027277, HPA027279, HPA028303" Supported Enhanced Mitochondria NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 70: Non-specific - Protein processing" "Cluster 44: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 32 Mitochondria "HPA027229: , HPA027277: , HPA027279: , HPA028303: " "unprognostic (8.53e-2)" "unprognostic (8.53e-2)" "unprognostic (4.56e-1)" "unprognostic (8.04e-2)" "unprognostic (1.86e-2)" "unprognostic (7.18e-2)" "unprognostic (1.07e-1)" "unprognostic (6.95e-2)" "unprognostic (6.23e-2)" "unprognostic (5.36e-3)" "unprognostic (1.01e-1)" "unprognostic (1.33e-3)" "unprognostic (3.28e-1)" "unprognostic (8.85e-3)" "unprognostic (2.43e-3)" "unprognostic (1.07e-1)" "unprognostic (2.20e-1)" "unprognostic (1.76e-1)" "unprognostic (1.04e-1)" "unprognostic (2.03e-2)" "unprognostic (1.61e-1)" "unprognostic (1.10e-1)" "unprognostic (1.05e-1)" "unprognostic (1.86e-2)" "unprognostic (1.62e-1)" "unprognostic (2.08e-1)" "unprognostic (1.55e-1)" "unprognostic (6.62e-2)" "unprognostic (3.73e-1)" COQ9 "C16orf49, DKFZP434K046" ENSG00000088682 "Coenzyme Q9" O75208 16 57447425-57461270 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubiquinone biosynthesis" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 239.3;tongue: 225.2" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040918 Supported Approved Mitochondria,Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 23: Choroid plexus - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 97: Non-specific - Cellular respiration" 46 "Mitochondria, Cytosol" "HPA040918: " "unprognostic (1.63e-2)" "unprognostic (3.57e-2)" "unprognostic (1.04e-2)" "potential prognostic unfavorable (6.65e-5)" "unprognostic (5.36e-2)" "unprognostic (2.61e-1)" "unprognostic (8.79e-2)" "potential prognostic favorable (3.69e-5)" "unprognostic (9.54e-3)" "unprognostic (1.11e-1)" "potential prognostic favorable (1.61e-9)" "unprognostic (5.19e-2)" "potential prognostic favorable (7.95e-5)" "unprognostic (2.43e-1)" "unprognostic (5.69e-2)" "unprognostic (8.53e-3)" "unprognostic (9.82e-2)" "unprognostic (1.33e-1)" "unprognostic (6.32e-2)" "unprognostic (9.27e-2)" "unprognostic (1.66e-1)" "unprognostic (2.72e-1)" "unprognostic (3.92e-1)" "unprognostic (1.97e-2)" "unprognostic (9.46e-2)" "unprognostic (2.32e-1)" "unprognostic (7.80e-2)" "unprognostic (4.64e-2)" "unprognostic (1.85e-1)" "unprognostic (8.49e-2)" "unprognostic (6.64e-2)" CORIN "ATC2, CRN, Lrp4, PRSC, TMPRSS10" ENSG00000145244 "Corin, serine peptidase" Q9Y5Q5 4 47593999-47838106 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrolase, Protease, Serine protease" Cardiomyopathy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "heart muscle: 53.4" "Cell type enriched" "Detected in many" 4 "Cardiomyocytes: 975.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Uterine cancer: 1.1" "Heart muscle - Cardiomyocytes, Pituitary gland - Undifferentiated cells (Pituitary gland), Spleen - Fibroblasts_2" "Region enhanced" "Detected in some" "basal ganglia: 2.6" "Low region specificity" "Detected in many" HPA070941 Approved "Nuclear bodies,Plasma membrane,Actin filaments" "Intracellular and membrane" Enzyme Yes No "Cluster 35: Non-specific - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 4 "Plasma membrane" "Nuclear bodies, Actin filaments" "HPA070941: " "unprognostic (4.37e-2)" "unprognostic (1.98e-1)" "unprognostic (1.82e-2)" "unprognostic (5.53e-2)" "unprognostic (1.31e-1)" "unprognostic (4.61e-2)" "unprognostic (1.04e-2)" "unprognostic (1.32e-1)" "unprognostic (5.67e-3)" "unprognostic (1.02e-1)" "unprognostic (3.24e-1)" "unprognostic (4.08e-2)" "unprognostic (2.06e-3)" CORO1A "coronin-1, HCORO1, p57" ENSG00000102879 "Coronin 1A" P31146 16 30182827-30189076 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 525.4;lymphoid tissue: 544.1" "Cell type enhanced" "Detected in many" "B-cells: 201.6;cDC: 203.1;Hofbauer cells: 438.6;Innate lymphoid cells: 103.9;Macrophages: 109.8;Megakaryocytes: 265.8;Monocyte progenitors: 212.8;monocytes: 266.7;Neutrophil progenitors: 239.4;Neutrophils: 377.8;NK-cells: 287.5;pDCs: 261.4;Plasma cells: 131.5;T-cells: 281.8" "Group enriched" "Detected in many" 7 "central nervous system macrophage: 44.4;leukocyte: 151.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 25 "Leukemia: 547.2;lymphoma: 754.1;Myeloma: 427.8" "Adipose subcutaneous - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Lung - Neutrophils_2, Skeletal muscle - Macrophages, Testis - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046473, HPA051132" Enhanced Approved Cytosol NA NA 42000000 "Cluster 29: Non-specific - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 51: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 35 Cytosol "CAB046473: , HPA051132: " "unprognostic (1.44e-1)" "unprognostic (1.07e-3)" "unprognostic (1.55e-2)" "unprognostic (6.44e-3)" "unprognostic (5.82e-2)" "unprognostic (1.40e-1)" "unprognostic (9.00e-3)" "unprognostic (5.91e-2)" "potential prognostic favorable (6.02e-5)" "unprognostic (3.41e-1)" "unprognostic (2.58e-2)" "unprognostic (1.45e-1)" "unprognostic (9.58e-2)" "unprognostic (7.84e-2)" "unprognostic (4.21e-2)" "unprognostic (1.75e-3)" "unprognostic (2.82e-1)" "unprognostic (2.70e-1)" "unprognostic (1.24e-1)" "unprognostic (1.05e-1)" "unprognostic (6.22e-2)" "unprognostic (9.80e-2)" "unprognostic (1.69e-3)" "unprognostic (2.10e-1)" "unprognostic (2.17e-2)" "unprognostic (5.59e-2)" "potential prognostic favorable (9.01e-5)" "unprognostic (2.07e-1)" "unprognostic (3.75e-3)" "unprognostic (9.89e-2)" "unprognostic (1.20e-1)" CORO1B coronin-2 ENSG00000172725 "Coronin 1B" Q9BR76 11 67435510-67443821 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 245.3;Enterocytes: 239.0;Esophageal apical cells: 395.2;Extravillous trophoblasts: 342.8;Hofbauer cells: 331.1" "Cell type enhanced" "Detected in many" "endothelial cell: 35.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 222.9" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Macrophages, Lung - Macrophages, Prostate - Prostate glandular cells, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017616, HPA040113, HPA070456" Enhanced Supported "Plasma membrane,Cytosol" NA NA 1000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 24: Non-specific - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 25 "Plasma membrane, Cytosol" "CAB017616: , HPA040113: , HPA070456: " "unprognostic (6.53e-2)" "unprognostic (8.95e-3)" "unprognostic (6.05e-2)" "unprognostic (1.55e-2)" "unprognostic (3.07e-1)" "unprognostic (1.85e-1)" "unprognostic (2.06e-1)" "unprognostic (8.74e-2)" "unprognostic (1.29e-2)" "unprognostic (2.23e-2)" "unprognostic (1.26e-1)" "unprognostic (3.65e-2)" "unprognostic (8.04e-2)" "unprognostic (5.38e-3)" "unprognostic (8.87e-2)" "unprognostic (1.21e-1)" "unprognostic (4.57e-2)" "unprognostic (6.71e-2)" "unprognostic (3.25e-1)" "unprognostic (1.19e-3)" "unprognostic (1.71e-1)" "unprognostic (8.79e-3)" "unprognostic (1.13e-1)" "unprognostic (2.59e-2)" "unprognostic (2.34e-1)" "unprognostic (2.38e-1)" "unprognostic (1.07e-1)" "unprognostic (2.33e-1)" "unprognostic (1.66e-1)" "unprognostic (4.45e-2)" "unprognostic (1.80e-1)" CORO1C "coronin-3, HCRNN4" ENSG00000110880 "Coronin 1C" Q9ULV4 12 108645109-108731526 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Platelets: 541.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Spleen - Fibroblasts_1, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041737 Approved NA NA 17000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 53 "HPA041737: " "unprognostic (6.66e-2)" "unprognostic (2.43e-1)" "unprognostic (7.92e-2)" "unprognostic (1.80e-1)" "unprognostic (5.12e-2)" "unprognostic (8.22e-2)" "unprognostic (1.49e-3)" "unprognostic (4.60e-2)" "unprognostic (1.98e-2)" "unprognostic (8.32e-3)" "potential prognostic favorable (4.41e-4)" "unprognostic (1.06e-1)" "unprognostic (3.92e-1)" "validated prognostic unfavorable (3.50e-6)" "validated prognostic unfavorable (6.54e-4)" "unprognostic (3.09e-3)" "potential prognostic unfavorable (9.94e-4)" "unprognostic (1.15e-1)" "unprognostic (6.27e-2)" "unprognostic (1.40e-2)" "unprognostic (1.84e-1)" "unprognostic (6.60e-3)" "unprognostic (7.85e-2)" "unprognostic (1.82e-1)" "unprognostic (3.57e-1)" "unprognostic (6.71e-3)" "unprognostic (1.28e-1)" "unprognostic (3.00e-2)" "unprognostic (2.98e-1)" "unprognostic (1.05e-1)" "unprognostic (2.64e-1)" CORO2A "IR10, WDR2" ENSG00000106789 "Coronin 2A" Q92828 9 98120975-98192637 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 33.0" "Cell type enhanced" "Detected in many" "Enterocytes: 242.6;Foveolar cells: 128.8;Neutrophil progenitors: 182.1;Papillary tip epithelial cells: 146.8;Prostatic hillock cells: 217.6;Sertoli cells: 207.2;Somatotrophs: 153.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "granulocytes: 11.4;monocytes: 7.8;T-cells: 11.9" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal medulla cells, Breast - Breast glandular cells, Skin - Keratinocyte (granular), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041161, HPA041302" Enhanced Approved "Vesicles,Plasma membrane,Basal body,Cytosol" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 1: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 11 "Plasma membrane, Cytosol" "Vesicles, Basal body" "HPA041161: , HPA041302: " "unprognostic (7.39e-2)" "unprognostic (3.05e-3)" "unprognostic (1.22e-1)" "unprognostic (3.73e-1)" "unprognostic (1.38e-1)" "unprognostic (1.84e-2)" "unprognostic (2.41e-1)" "unprognostic (8.18e-2)" "unprognostic (1.64e-1)" "unprognostic (5.30e-1)" "unprognostic (1.86e-2)" "unprognostic (5.57e-2)" "unprognostic (3.47e-3)" "unprognostic (3.92e-2)" "unprognostic (7.41e-2)" "unprognostic (2.76e-1)" "unprognostic (8.25e-2)" "unprognostic (1.55e-1)" "unprognostic (8.31e-3)" "potential prognostic unfavorable (4.47e-4)" "unprognostic (7.70e-2)" "unprognostic (3.54e-1)" "unprognostic (1.80e-1)" "unprognostic (1.30e-2)" "unprognostic (5.02e-1)" "unprognostic (1.02e-1)" "unprognostic (4.88e-2)" "unprognostic (4.04e-2)" "unprognostic (1.52e-1)" CORO2B "ClipinC, KIAA0925" ENSG00000103647 "Coronin 2B" Q9UQ03 15 68578993-68727806 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 94.9;retina: 41.9" "Cell type enhanced" "Detected in many" "Bergmann glia: 112.6;Choroid plexus epithelial cells: 125.2;Cone photoreceptor cells: 190.5;Ependymal cells: 292.9;Fibro-adipogenic progenitors: 129.1;Oligodendrocytes: 163.6;Podocytes: 369.9;Retinal amacrine cells: 124.0;Retinal bipolar cells: 214.1;Retinal ganglion cells: 173.8;Rod photoreceptor cells: 222.2;Tuft cells: 172.9" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" 8 "Glioblastoma Multiforme (TCGA): 65.3;Skin Cutaneous Melanoma (TCGA): 43.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.2" "Lineage enriched" "Detected in single" 13 "B-cells: 1.2" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Colon - Enteric glia cells, Kidney - Endothelial cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017960 Enhanced Supported Approved "Plasma membrane,Focal adhesion sites" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 1 "Plasma membrane, Focal adhesion sites" "HPA017960: " "unprognostic (6.93e-2)" "unprognostic (1.25e-1)" "unprognostic (4.27e-1)" "unprognostic (5.39e-2)" "unprognostic (2.51e-1)" "unprognostic (1.84e-1)" "unprognostic (2.03e-2)" "unprognostic (5.07e-1)" "unprognostic (1.47e-2)" "unprognostic (9.58e-2)" "potential prognostic favorable (2.47e-5)" "unprognostic (6.37e-2)" "unprognostic (2.33e-1)" "unprognostic (3.02e-2)" "unprognostic (3.71e-1)" "unprognostic (1.02e-1)" "unprognostic (1.33e-2)" "unprognostic (1.97e-3)" "unprognostic (2.47e-3)" "unprognostic (1.29e-1)" "potential prognostic unfavorable (6.30e-4)" "unprognostic (1.05e-2)" "unprognostic (2.60e-1)" "unprognostic (1.74e-2)" "unprognostic (9.44e-2)" CORO6 "ClipinE, FLJ14871" ENSG00000167549 "Coronin 6" Q6QEF8 17 29614756-29622912 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "skeletal muscle: 342.1;tongue: 180.0" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 43.4;Brain inhibitory neurons: 60.5;Cardiomyocytes: 74.8;Extravillous trophoblasts: 61.5;Myonuclei: 117.6;Myosatellite cells: 33.9;Other brain neurons: 49.1;Thymic myoid cells: 134.6" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 13.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021556 Approved "Golgi apparatus" NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 6: Leukemia - Signal transduction" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 3 "Golgi apparatus" "HPA021556: " "potential prognostic unfavorable (3.17e-7)" "unprognostic (5.42e-2)" "unprognostic (8.70e-2)" "unprognostic (1.42e-2)" "unprognostic (3.78e-2)" "unprognostic (3.36e-2)" "unprognostic (4.09e-2)" "unprognostic (1.81e-1)" "unprognostic (7.17e-2)" "unprognostic (2.12e-1)" "unprognostic (4.30e-2)" "unprognostic (1.47e-1)" "unprognostic (5.49e-2)" "unprognostic (2.71e-1)" "unprognostic (3.32e-2)" "unprognostic (4.52e-2)" CORO7 "FLJ22021, POD1" ENSG00000262246 "Coronin 7" P57737 16 4354542-4425705 "Predicted intracellular proteins" "Protein transport, Transport" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 65.6" "Cell type enhanced" "Detected in some" "Astrocytes: 10.0;Bergmann glia: 9.0;Brain excitatory neurons: 16.3;Brain inhibitory neurons: 14.3;Choroid plexus epithelial cells: 7.6;Microglia: 45.2;Oligodendrocyte progenitor cells: 23.2;Oligodendrocytes: 40.7;Other brain neurons: 15.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Myeloma: 56.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041657, HPA053586" Uncertain NA NA 24000 "Cluster 25: Non-specific - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 11: White matter - Signal transduction" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 22: Non-specific - Basic cellular functions" 6 "HPA041657: , HPA053586: " "unprognostic (3.49e-1)" "unprognostic (2.47e-1)" "unprognostic (2.88e-1)" "unprognostic (3.54e-2)" "unprognostic (9.68e-2)" "unprognostic (1.36e-1)" "unprognostic (1.45e-1)" "unprognostic (4.95e-3)" "unprognostic (4.29e-2)" "unprognostic (3.59e-1)" "unprognostic (3.98e-2)" "unprognostic (4.62e-1)" "unprognostic (8.84e-3)" "unprognostic (1.66e-3)" "unprognostic (1.50e-1)" "unprognostic (5.29e-3)" "unprognostic (2.16e-1)" "unprognostic (1.15e-1)" "unprognostic (1.17e-1)" "unprognostic (6.71e-2)" "unprognostic (1.43e-2)" "unprognostic (1.41e-2)" "unprognostic (5.11e-2)" "unprognostic (1.11e-1)" "unprognostic (9.45e-2)" "unprognostic (4.23e-3)" "unprognostic (1.87e-1)" "unprognostic (1.19e-1)" "unprognostic (2.21e-3)" "unprognostic (8.67e-2)" "unprognostic (4.22e-2)" CORO7-PAM16 ENSG00000103426 "CORO7-PAM16 readthrough" 16 4340251-4420494 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041657, HPA053586, HPA062721" Uncertain Approved Nucleoplasm,Microtubules,Mitochondria NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 67: Plasma cells - Plasma cell differentiation" "Nucleoplasm, Mitochondria" Microtubules "HPA041657: , HPA053586: , HPA062721: " CORT "MGC32686, SST2" ENSG00000241563 Cortistatin O00230 1 10450031-10451998 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 33 "brain: 66.5" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 2.2;Brain inhibitory neurons: 15.7;Early spermatids: 4.3;Ependymal cells: 2.6;Hepatic stellate cells: 6.5;Late primary spermatocytes: 5.1;Late spermatids: 8.1;Oligodendrocytes: 1.9;Other brain neurons: 3.3" "Cell type enhanced" "Detected in many" "MGE interneuron: 67.7;splatter: 109.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted in brain" Hormone NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 11 "unprognostic (8.07e-2)" "unprognostic (1.07e-1)" "potential prognostic favorable (1.50e-4)" "unprognostic (2.85e-1)" "unprognostic (1.37e-1)" "unprognostic (2.00e-2)" "unprognostic (1.69e-2)" "unprognostic (1.99e-1)" "unprognostic (2.53e-2)" "unprognostic (1.09e-1)" COTL1 CLP ENSG00000103187 "Coactosin like F-actin binding protein 1" Q14019 16 84565596-84618078 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Chaperone" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 349.9" "Cell type enhanced" "Detected in many" "cDC: 1071.5;Extravillous trophoblasts: 2134.1;Hofbauer cells: 597.9;Kupffer cells: 978.8;Megakaryocytes: 704.7;Monocyte progenitors: 523.9;monocytes: 1347.0;Neutrophil progenitors: 521.4;Neutrophils: 1408.0;Platelets: 978.7" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 222.6;leukocyte: 219.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 2442.3;eosinophil: 3426.1;intermediate monocyte: 4071.9;myeloid DC: 2397.3;neutrophil: 1764.5;non-classical monocyte: 4600.6" "Group enriched" "Detected in all" 5 "dendritic cells: 2397.3;granulocytes: 3426.1;monocytes: 4600.6" "Low cancer specificity" "Detected in all" "Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008918, CAB062328" Enhanced Supported Cytosol NA NA 16000000 "Cluster 7: Non-specific - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 5 Cytosol "CAB062328: , HPA008918: " "unprognostic (1.39e-1)" "unprognostic (1.19e-2)" "unprognostic (3.54e-2)" "unprognostic (4.28e-1)" "unprognostic (3.24e-2)" "unprognostic (2.92e-1)" "unprognostic (9.16e-3)" "unprognostic (2.99e-1)" "unprognostic (1.95e-2)" "unprognostic (2.01e-2)" "unprognostic (1.27e-2)" "unprognostic (3.62e-2)" "unprognostic (1.69e-3)" "unprognostic (1.39e-1)" "unprognostic (1.60e-1)" "unprognostic (1.64e-1)" "unprognostic (7.64e-2)" "unprognostic (5.75e-2)" "unprognostic (5.60e-3)" "unprognostic (3.59e-2)" "unprognostic (2.59e-1)" "unprognostic (3.89e-2)" "unprognostic (1.66e-1)" "unprognostic (1.03e-1)" "unprognostic (6.34e-2)" "unprognostic (4.48e-2)" "unprognostic (1.58e-1)" "unprognostic (1.55e-1)" "unprognostic (1.02e-2)" "potential prognostic unfavorable (6.69e-4)" "unprognostic (1.10e-1)" COX10 ENSG00000006695 "Cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10" Q12887 17 14069490-14231736 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Heme biosynthesis, Lipid metabolism" Transferase "Disease variant, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 40.5;tongue: 41.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 191.3;Late spermatids: 181.4;Myonuclei: 158.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032005, HPA032006" Supported Supported Nucleoli,Mitochondria,Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 23: Choroid plexus - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 55: Myocytes - Oxidative muscle function" 3 Mitochondria "Nucleoli, Cytosol" "HPA032005: , HPA032006: " "unprognostic (2.13e-1)" "unprognostic (3.83e-2)" "unprognostic (9.82e-2)" "unprognostic (1.16e-1)" "unprognostic (3.07e-2)" "unprognostic (5.44e-2)" "unprognostic (4.14e-2)" "unprognostic (2.21e-3)" "unprognostic (1.88e-1)" "unprognostic (3.49e-3)" "unprognostic (1.13e-3)" "unprognostic (2.95e-3)" "unprognostic (1.81e-2)" "unprognostic (1.64e-1)" "unprognostic (6.85e-2)" "unprognostic (2.81e-2)" "unprognostic (2.62e-1)" "unprognostic (6.10e-2)" "unprognostic (3.22e-1)" "unprognostic (3.84e-1)" "unprognostic (1.09e-1)" "unprognostic (1.39e-1)" "unprognostic (2.63e-3)" "unprognostic (8.03e-3)" "unprognostic (7.08e-3)" "unprognostic (8.14e-2)" "unprognostic (1.32e-2)" "unprognostic (9.04e-3)" "unprognostic (1.94e-1)" "unprognostic (4.41e-3)" "unprognostic (1.85e-1)" COX11 COX11P ENSG00000166260 "Cytochrome c oxidase copper chaperone COX11" Q9Y6N1 17 54951902-54968703 "Essential proteins, Predicted membrane proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Smooth muscle cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044020 Approved NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 7 "HPA044020: " "unprognostic (1.46e-1)" "unprognostic (2.22e-2)" "unprognostic (1.95e-1)" "unprognostic (1.34e-2)" "unprognostic (1.75e-2)" "unprognostic (2.30e-1)" "unprognostic (1.52e-2)" "unprognostic (7.65e-2)" "unprognostic (2.96e-1)" "unprognostic (1.63e-1)" "potential prognostic favorable (1.07e-7)" "unprognostic (3.78e-2)" "unprognostic (1.59e-1)" "unprognostic (4.57e-1)" "unprognostic (1.08e-2)" "unprognostic (1.08e-1)" "unprognostic (4.57e-2)" "unprognostic (2.11e-1)" "unprognostic (1.39e-3)" "unprognostic (1.46e-1)" "unprognostic (3.53e-2)" "unprognostic (2.17e-2)" "unprognostic (5.16e-2)" "unprognostic (1.38e-3)" "potential prognostic favorable (4.34e-5)" "unprognostic (6.99e-2)" "unprognostic (3.28e-1)" "unprognostic (3.68e-1)" "unprognostic (2.95e-1)" "unprognostic (3.93e-1)" "unprognostic (3.86e-2)" COX14 "C12orf62, MGC14288" ENSG00000178449 "Cytochrome c oxidase assembly factor COX14" Q96I36 12 50112082-50120457 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial secretory cells: 37.3;Gastric chief cells: 91.7;Mucous neck cells: 57.3;Parietal cells: 267.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044618, HPA062014" Approved Supported Mitochondria NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 38: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 3 Mitochondria "HPA044618: , HPA062014: " "unprognostic (1.02e-1)" "unprognostic (2.96e-2)" "unprognostic (1.38e-3)" "unprognostic (4.95e-2)" "unprognostic (1.53e-1)" "unprognostic (2.40e-2)" "unprognostic (1.51e-1)" "unprognostic (3.59e-2)" "unprognostic (1.09e-3)" "unprognostic (1.06e-2)" "unprognostic (2.02e-1)" "unprognostic (1.07e-1)" "unprognostic (6.09e-3)" "unprognostic (5.66e-3)" "unprognostic (2.67e-1)" "unprognostic (5.32e-2)" "unprognostic (5.81e-3)" "unprognostic (1.23e-1)" "unprognostic (2.47e-1)" "unprognostic (1.90e-2)" "unprognostic (1.86e-1)" "unprognostic (9.53e-2)" "unprognostic (1.12e-1)" "unprognostic (1.19e-1)" "unprognostic (1.17e-2)" "unprognostic (3.00e-1)" "unprognostic (2.52e-1)" "unprognostic (1.83e-2)" "unprognostic (5.40e-2)" COX15 CEMCOX2 ENSG00000014919 "Cytochrome c oxidase assembly homolog COX15" Q7KZN9 10 99710868-99732127 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Heme biosynthesis" Oxidoreductase "Disease variant, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 29.4;Loop of henle epithelial cells: 23.1;Papillary tip epithelial cells: 24.4;Podocytes: 24.5;Proximal tubule cells: 20.5;Renal collecting duct intercalated cells: 26.2;Renal collecting duct principal cells: 25.8;Renal connecting tubule cells: 21.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037727, HPA037728, HPA066096" Uncertain Supported Nucleoplasm,Mitochondria NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 52: Non-specific - Mitochondria" "Cluster 105: Non-specific - Mixed function" 28 Mitochondria Nucleoplasm "HPA037727: , HPA037728: , HPA066096: " "unprognostic (3.81e-2)" "unprognostic (1.39e-1)" "unprognostic (2.47e-2)" "unprognostic (4.63e-1)" "unprognostic (5.31e-2)" "unprognostic (7.36e-2)" "unprognostic (3.75e-2)" "potential prognostic favorable (9.84e-5)" "unprognostic (5.41e-2)" "unprognostic (3.01e-1)" "potential prognostic favorable (6.26e-7)" "unprognostic (5.19e-3)" "unprognostic (4.87e-2)" "unprognostic (6.80e-2)" "unprognostic (1.50e-1)" "unprognostic (1.04e-1)" "unprognostic (2.05e-1)" "unprognostic (7.30e-2)" "unprognostic (1.98e-1)" "unprognostic (6.08e-2)" "unprognostic (3.46e-3)" "unprognostic (1.44e-1)" "unprognostic (8.59e-2)" "unprognostic (4.79e-2)" "unprognostic (2.73e-2)" "unprognostic (5.23e-2)" "unprognostic (1.00e-1)" "unprognostic (1.25e-2)" "unprognostic (1.84e-1)" "unprognostic (3.04e-2)" "potential prognostic favorable (4.12e-4)" COX16 "C14orf112, HSPC203" ENSG00000133983 "Cytochrome c oxidase assembly factor COX16" Q9P0S2 14 70325081-70416984 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric chief cells: 93.9;Mucous neck cells: 57.2;Oocytes: 124.3;Parietal cells: 146.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062659 Uncertain Supported Mitochondria NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 21: Non-specific - Metabolism" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 97: Non-specific - Cellular respiration" 3 Mitochondria "HPA062659: " "unprognostic (2.60e-2)" "unprognostic (2.24e-1)" "unprognostic (7.70e-2)" "unprognostic (3.11e-1)" "unprognostic (1.05e-1)" "unprognostic (1.37e-1)" "unprognostic (7.48e-2)" "unprognostic (9.49e-2)" "potential prognostic unfavorable (2.53e-4)" "potential prognostic unfavorable (7.88e-5)" "potential prognostic favorable (7.24e-5)" "unprognostic (2.23e-2)" "unprognostic (2.33e-2)" "unprognostic (5.01e-2)" "unprognostic (2.34e-3)" "potential prognostic unfavorable (5.30e-4)" "unprognostic (1.07e-1)" "unprognostic (1.00e-3)" "unprognostic (1.20e-1)" "unprognostic (1.44e-2)" "potential prognostic unfavorable (8.55e-4)" "unprognostic (3.70e-1)" "unprognostic (8.63e-2)" "unprognostic (1.88e-1)" "unprognostic (4.27e-1)" "unprognostic (2.59e-1)" "unprognostic (8.01e-2)" "unprognostic (5.15e-2)" "unprognostic (1.47e-1)" "unprognostic (1.81e-1)" "unprognostic (1.02e-1)" COX17 ENSG00000138495 "Cytochrome c oxidase copper chaperone COX17" Q14061 3 119654513-119677454 "Cancer-related genes, Essential proteins, Predicted intracellular proteins" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 727.3;Hepatocytes: 722.1;Megakaryocytes: 698.5;Parietal cells: 1166.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042226, HPA048158" Supported Supported Mitochondria NA NA 140000 "Cluster 32: Basophils - Transcription" "Cluster 52: Non-specific - Cellular respiration" "Cluster 44: Non-specific - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 97: Non-specific - Cellular respiration" 8 Mitochondria "HPA042226: , HPA048158: " "unprognostic (1.38e-1)" "unprognostic (2.14e-3)" "unprognostic (5.38e-2)" "unprognostic (3.31e-3)" "unprognostic (2.49e-2)" "unprognostic (1.93e-1)" "potential prognostic unfavorable (4.95e-5)" "unprognostic (3.86e-2)" "unprognostic (7.02e-3)" "unprognostic (3.03e-2)" "unprognostic (3.67e-1)" "unprognostic (1.19e-3)" "unprognostic (1.40e-1)" "unprognostic (1.21e-1)" "unprognostic (9.99e-3)" "unprognostic (6.16e-2)" "unprognostic (4.80e-1)" "unprognostic (2.15e-1)" "unprognostic (1.22e-1)" "unprognostic (7.75e-3)" "unprognostic (1.30e-1)" "unprognostic (8.42e-2)" "unprognostic (2.35e-2)" "unprognostic (1.09e-1)" "unprognostic (3.57e-1)" "unprognostic (3.05e-2)" "unprognostic (2.46e-1)" "unprognostic (2.88e-2)" "unprognostic (2.61e-1)" "unprognostic (5.65e-2)" "unprognostic (1.93e-1)" COX18 "FLJ38991, OXA1L2" ENSG00000163626 "Cytochrome c oxidase assembly factor COX18" Q8N8Q8 4 73052362-73069755 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046772, HPA049489" Approved NA NA "Cluster 76: Non-specific - Metabolism" "Cluster 9: Non-specific - Receptor signaling" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 44: Plasma cells - Antibody production & secretion" "HPA046772: , HPA049489: " "unprognostic (2.04e-2)" "unprognostic (1.61e-1)" "unprognostic (1.41e-1)" "unprognostic (2.87e-1)" "unprognostic (7.83e-3)" "unprognostic (2.68e-1)" "unprognostic (2.98e-1)" "unprognostic (3.29e-1)" "unprognostic (8.03e-2)" COX19 MGC104475 ENSG00000240230 "Cytochrome c oxidase assembly factor COX19" Q49B96 7 898778-975549 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021226 Approved Supported Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 24: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 67: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 2 Cytosol "HPA021226: " "unprognostic (2.67e-1)" "unprognostic (6.57e-2)" "unprognostic (1.79e-1)" "unprognostic (3.83e-2)" "unprognostic (6.35e-3)" "unprognostic (1.58e-1)" "unprognostic (8.62e-2)" "unprognostic (1.31e-1)" "unprognostic (1.10e-1)" "unprognostic (5.21e-3)" "potential prognostic unfavorable (2.94e-4)" "unprognostic (8.77e-2)" "unprognostic (2.28e-1)" "unprognostic (4.95e-2)" "unprognostic (1.42e-2)" "unprognostic (2.77e-3)" "unprognostic (6.36e-2)" "unprognostic (5.55e-2)" "unprognostic (2.54e-2)" "unprognostic (6.96e-2)" "unprognostic (1.49e-1)" "unprognostic (1.38e-1)" "potential prognostic unfavorable (4.58e-5)" "unprognostic (6.28e-2)" "unprognostic (3.18e-1)" "unprognostic (1.15e-1)" "unprognostic (3.35e-1)" "unprognostic (2.18e-1)" "unprognostic (3.14e-1)" "unprognostic (1.09e-2)" "unprognostic (1.72e-1)" COX20 "FAM36A, FLJ43269" ENSG00000203667 "Cytochrome c oxidase assembly factor COX20" Q5RI15 1 244835616-244845057 "Disease related genes, Essential proteins, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Epicardial cells: 1571.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043617, HPA045490" Approved Enhanced Mitochondria NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 76: Non-specific - Metabolism" "Cluster 25: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 19 Mitochondria "HPA043617: , HPA045490: " "unprognostic (1.85e-2)" "unprognostic (6.25e-2)" "unprognostic (1.07e-1)" "unprognostic (7.95e-2)" "unprognostic (2.67e-1)" "unprognostic (2.77e-1)" "unprognostic (1.12e-1)" "potential prognostic unfavorable (4.07e-4)" "unprognostic (2.26e-3)" "potential prognostic favorable (6.85e-5)" "unprognostic (6.89e-2)" "unprognostic (1.28e-1)" "unprognostic (1.99e-2)" "potential prognostic unfavorable (4.81e-4)" "unprognostic (1.61e-1)" "unprognostic (3.05e-1)" "unprognostic (1.23e-3)" "unprognostic (2.96e-3)" "unprognostic (9.71e-2)" "unprognostic (3.37e-2)" "unprognostic (3.26e-2)" "unprognostic (1.36e-2)" "unprognostic (1.12e-1)" "unprognostic (2.08e-2)" "unprognostic (3.83e-2)" "unprognostic (3.37e-3)" "unprognostic (1.42e-1)" "unprognostic (3.03e-1)" "unprognostic (3.42e-1)" COX4I1 "COX4, COX4-1, COXIV, COXIV-1" ENSG00000131143 "Cytochrome c oxidase subunit 4I1" P13073 16 85798633-85807068 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Colonocytes: 2801.3;Enterocytes: 3310.7;Esophageal apical cells: 2869.8;Esophageal basal cells: 2552.8;Esophageal suprabasal cells: 3208.9;Parietal cells: 4069.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002485, CAB004080, HPA070836" Supported Supported Mitochondria NA NA 46000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 45: Non-specific - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 97: Non-specific - Cellular respiration" 115 Mitochondria "CAB004080: , HPA002485: , HPA070836: " "unprognostic (1.49e-2)" "unprognostic (8.28e-2)" "unprognostic (2.77e-1)" "unprognostic (8.22e-3)" "unprognostic (2.26e-1)" "unprognostic (2.44e-2)" "unprognostic (2.82e-1)" "unprognostic (2.35e-2)" "unprognostic (1.18e-2)" "unprognostic (3.27e-2)" "unprognostic (3.08e-2)" "unprognostic (8.61e-3)" "unprognostic (2.69e-3)" "unprognostic (9.38e-2)" "unprognostic (2.94e-1)" "unprognostic (1.30e-1)" "unprognostic (3.12e-2)" "unprognostic (3.45e-2)" "unprognostic (2.46e-1)" "unprognostic (3.88e-2)" "unprognostic (4.65e-1)" "unprognostic (3.35e-2)" "unprognostic (1.04e-1)" "unprognostic (3.45e-1)" "unprognostic (2.10e-1)" "unprognostic (1.34e-1)" "unprognostic (3.96e-1)" "unprognostic (3.69e-2)" "unprognostic (1.50e-1)" "unprognostic (2.35e-1)" "unprognostic (2.31e-1)" COX4I2 "COX4-2, COX4B, COX4L2, COXIV-2, dJ857M17.2" ENSG00000131055 "Cytochrome c oxidase subunit 4I2" Q96KJ9 20 31637912-31645006 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 48.5;placenta: 108.4" "Cell type enhanced" "Detected in some" "Oocytes: 64.5;Pericytes: 328.8;Vascular smooth muscle cells: 148.5" "Group enriched" "Detected in some" 33 "pericyte: 62.7;vascular associated smooth muscle cell: 64.6" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 33.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "lymphoma: 2.0;Neuroblastoma: 1.7" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Minor Salivary Gland - Endothelial cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 55: Lymphoma - Immune response" "Cluster 110: Mural cells - ECM organization" 2 "unprognostic (4.48e-2)" "unprognostic (1.69e-1)" "unprognostic (3.89e-2)" "potential prognostic favorable (1.91e-4)" "unprognostic (7.07e-3)" "unprognostic (1.01e-1)" "unprognostic (2.34e-1)" "unprognostic (1.45e-1)" "potential prognostic favorable (1.24e-5)" "unprognostic (1.51e-1)" "unprognostic (2.52e-3)" "potential prognostic favorable (3.83e-6)" "potential prognostic unfavorable (2.17e-4)" "unprognostic (4.72e-2)" "unprognostic (3.43e-2)" "potential prognostic favorable (2.71e-4)" "unprognostic (2.26e-1)" "unprognostic (1.43e-2)" "unprognostic (1.54e-1)" "unprognostic (1.15e-1)" "unprognostic (3.51e-2)" "unprognostic (1.08e-2)" "unprognostic (2.86e-2)" "unprognostic (2.91e-2)" "unprognostic (6.71e-3)" "unprognostic (1.21e-1)" "unprognostic (1.47e-1)" "unprognostic (2.06e-2)" "unprognostic (6.51e-2)" "unprognostic (3.63e-1)" "unprognostic (3.47e-3)" COX5A ENSG00000178741 "Cytochrome c oxidase subunit 5A" P20674 15 74919791-74938083 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1666.8;skeletal muscle: 1561.5;tongue: 1618.5" "Cell type enhanced" "Detected in many" "Colonocytes: 1154.4;Enteric stem cells: 1034.6;Enteric transient amplifying cells: 1176.7;Enterocytes: 1107.1;Esophageal apical cells: 2058.2;Esophageal suprabasal cells: 1112.9;Late primary spermatocytes: 1221.0;Late spermatids: 1085.7;Parietal cells: 1967.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027526 Supported NA NA 200000 "Cluster 13: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cellular respiration" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 97: Non-specific - Cellular respiration" 33 "HPA027526: " "unprognostic (1.42e-2)" "unprognostic (1.39e-1)" "unprognostic (7.04e-3)" "unprognostic (7.82e-2)" "unprognostic (1.80e-2)" "unprognostic (1.53e-2)" "unprognostic (1.73e-1)" "unprognostic (3.25e-1)" "unprognostic (2.18e-2)" "unprognostic (7.50e-3)" "unprognostic (4.18e-1)" "unprognostic (1.73e-1)" "unprognostic (6.72e-3)" "unprognostic (5.56e-2)" "potential prognostic unfavorable (9.41e-7)" "potential prognostic unfavorable (2.25e-4)" "unprognostic (8.71e-3)" "unprognostic (4.22e-2)" "unprognostic (1.32e-1)" "unprognostic (2.46e-1)" "unprognostic (4.57e-2)" "unprognostic (2.50e-1)" "unprognostic (7.65e-2)" "unprognostic (5.15e-2)" "unprognostic (1.65e-1)" "unprognostic (5.80e-2)" "unprognostic (5.11e-2)" "unprognostic (1.70e-1)" "unprognostic (2.18e-1)" "unprognostic (2.20e-1)" "unprognostic (4.44e-2)" COX5B ENSG00000135940 "Cytochrome c oxidase subunit 5B" P10606 2 97646062-97648383 "Metabolic proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1143.7;skeletal muscle: 1249.4" "Cell type enhanced" "Detected in all" "Colonocytes: 2717.1;Enteric transient amplifying cells: 1750.3;Enterocytes: 2408.2;Esophageal apical cells: 1740.3;Esophageal suprabasal cells: 2249.9;Parietal cells: 3679.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034517 Supported Enhanced Mitochondria,Acrosome NA NA 370000 "Cluster 29: Non-specific - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 27: Non-specific - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 97: Non-specific - Cellular respiration" 39 Mitochondria Acrosome "HPA034517: " "unprognostic (5.84e-2)" "unprognostic (1.55e-1)" "unprognostic (2.01e-1)" "unprognostic (2.10e-2)" "unprognostic (3.21e-1)" "unprognostic (1.50e-1)" "unprognostic (2.28e-1)" "unprognostic (3.73e-1)" "unprognostic (1.88e-3)" "unprognostic (9.83e-3)" "unprognostic (1.50e-2)" "unprognostic (1.90e-1)" "unprognostic (2.32e-2)" "unprognostic (3.19e-1)" "unprognostic (1.69e-2)" "unprognostic (3.39e-3)" "unprognostic (1.93e-1)" "unprognostic (3.54e-1)" "unprognostic (4.87e-2)" "unprognostic (3.95e-2)" "unprognostic (2.28e-1)" "unprognostic (3.01e-2)" "unprognostic (3.46e-1)" "unprognostic (9.85e-2)" "unprognostic (7.46e-2)" "unprognostic (5.23e-2)" "unprognostic (7.16e-2)" "unprognostic (6.43e-2)" "unprognostic (1.52e-1)" "unprognostic (1.73e-1)" "unprognostic (3.81e-2)" COX6A1 "COX6A, COX6AL" ENSG00000111775 "Cytochrome c oxidase subunit 6A1" P12074 12 120438090-120440737 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Predicted membrane proteins" Oxidoreductase "Charcot-Marie-Tooth disease, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1831.8" "Cell type enhanced" "Detected in many" "Colonocytes: 295.8;Enteric stem cells: 169.5;Enteric transient amplifying cells: 240.1;Enterocytes: 443.9;Epididymal efferent duct ciliated cells: 145.2;Gastric chief cells: 170.4;Parietal cells: 910.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062394 Approved Supported "Mitochondria,Principal piece" NA NA 110000 "Cluster 13: Non-specific - Mitochondria" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 45: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 4 Mitochondria "Principal piece" "HPA062394: " "unprognostic (8.09e-3)" "unprognostic (9.88e-2)" "unprognostic (3.54e-1)" "unprognostic (5.31e-3)" "potential prognostic favorable (6.23e-4)" "unprognostic (5.75e-2)" "unprognostic (1.91e-1)" "unprognostic (1.16e-1)" "unprognostic (9.85e-3)" "unprognostic (1.08e-1)" "unprognostic (8.83e-2)" "potential prognostic unfavorable (1.27e-4)" "unprognostic (1.57e-1)" "unprognostic (1.42e-1)" "unprognostic (1.07e-3)" "unprognostic (2.68e-2)" "unprognostic (2.08e-1)" "unprognostic (1.27e-1)" "unprognostic (1.91e-1)" "unprognostic (1.49e-2)" "unprognostic (1.72e-1)" "unprognostic (3.35e-1)" "unprognostic (6.10e-2)" "unprognostic (3.74e-1)" "unprognostic (2.65e-1)" "unprognostic (1.26e-1)" "unprognostic (4.73e-2)" "unprognostic (1.35e-1)" "unprognostic (1.80e-1)" "unprognostic (1.98e-1)" "unprognostic (6.43e-2)" COX6A2 "COX6AH, COXVIa-M, COXVIAH" ENSG00000156885 "Cytochrome c oxidase subunit 6A2" Q02221 16 31427731-31428360 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" Oxidoreductase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 41 "heart muscle: 4887.8;skeletal muscle: 6326.0;tongue: 1952.3" "Cell type enriched" "Detected in some" 17 "Thymic myoid cells: 1525.5" "Cell type enriched" "Detected in some" 4 "vascular associated smooth muscle cell: 12.9" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 37.1" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 151 "NK-cell: 15.0" "Lineage enriched" "Detected in single" 151 "NK-cells: 15.0" "Group enriched" "Detected in some" 5 "Myeloma: 3.3;Sarcoma: 1.0" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 20: Myeloma - Immune response" "Cluster 46: Skeletal myocytes - Muscle structure & formation" "unprognostic (6.09e-2)" "potential prognostic favorable (6.20e-4)" "unprognostic (7.21e-2)" "unprognostic (1.30e-2)" "potential prognostic favorable (1.54e-4)" "unprognostic (3.60e-2)" "unprognostic (2.26e-1)" "unprognostic (9.47e-3)" "unprognostic (9.31e-2)" "unprognostic (9.79e-2)" "unprognostic (1.51e-1)" "unprognostic (4.10e-2)" COX6B1 "COX6B, COXG" ENSG00000126267 "Cytochrome c oxidase subunit 6B1" P14854 19 35648323-35658782 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 2287.9" "Cell type enhanced" "Detected in many" "Colonocytes: 1932.4;Enterocytes: 1982.1;Esophageal apical cells: 3024.0;Esophageal suprabasal cells: 2038.1;Parietal cells: 3587.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004192 Supported Supported "Mitochondria,Principal piece" NA NA 75000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 52: Non-specific - Cellular respiration" "Cluster 14: Neurons - Synaptic function" "Cluster 4: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 8 Mitochondria "Principal piece" "HPA004192: " "unprognostic (1.74e-2)" "unprognostic (2.22e-1)" "unprognostic (8.77e-2)" "unprognostic (1.04e-3)" "unprognostic (1.31e-3)" "unprognostic (1.47e-1)" "unprognostic (2.99e-2)" "unprognostic (2.75e-1)" "unprognostic (1.44e-1)" "unprognostic (2.73e-3)" "unprognostic (1.66e-2)" "unprognostic (2.52e-3)" "unprognostic (1.94e-1)" "unprognostic (1.17e-1)" "unprognostic (1.03e-2)" "potential prognostic unfavorable (7.27e-4)" "unprognostic (9.54e-2)" "unprognostic (2.27e-2)" "unprognostic (3.26e-1)" "unprognostic (1.83e-1)" "unprognostic (2.53e-2)" "unprognostic (7.90e-2)" "unprognostic (1.43e-1)" "unprognostic (1.51e-1)" "unprognostic (1.97e-1)" "unprognostic (9.40e-2)" "unprognostic (3.49e-1)" "unprognostic (2.19e-1)" "unprognostic (1.53e-1)" "unprognostic (1.32e-1)" "unprognostic (2.60e-1)" COX6B2 "COXVIB2, CT59, FLJ32865" ENSG00000160471 "Cytochrome c oxidase subunit 6B2" Q6YFQ2 19 55349306-55354719 "Metabolic proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "testis: 87.4" "Cell type enhanced" "Detected in some" "Colonocytes: 7.9;Early primary spermatocytes: 27.6;Early spermatids: 13.2;Late primary spermatocytes: 65.2;Respiratory deuterosomal cells: 6.2" "Cell type enhanced" "Detected in some" "ependymal cell: 3.3" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 12.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Prostate - Urothelial cells, Spleen - Neutrophils_2, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA035014 Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 79: Testis - Spermatogenesis" "Cluster 48: Non-specific - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 2 "Nucleoplasm, Plasma membrane, Cytosol" "HPA035014: " "unprognostic (9.00e-3)" "unprognostic (5.72e-2)" "unprognostic (6.78e-2)" "unprognostic (2.40e-1)" "unprognostic (1.77e-1)" "unprognostic (2.72e-2)" "unprognostic (1.75e-2)" "unprognostic (4.64e-3)" "unprognostic (2.40e-3)" "unprognostic (1.14e-1)" "unprognostic (5.56e-2)" "potential prognostic unfavorable (1.33e-4)" "unprognostic (4.76e-2)" "unprognostic (2.65e-2)" "unprognostic (2.51e-2)" "unprognostic (8.55e-2)" "unprognostic (9.35e-2)" "unprognostic (1.33e-2)" COX6C ENSG00000164919 "Cytochrome c oxidase subunit 6C" P09669 8 99873200-99893707 "Metabolic proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Decidual stromal cells: 2066.0;Hepatocytes: 2106.9;Parietal cells: 5086.2;Syncytiotrophoblasts: 2329.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "breast cancer: 636.0" "Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014295, CAB016244" Enhanced Enhanced Mitochondria NA NA 67000 "Cluster 6: T-cells - T-cell receptor" "Cluster 52: Non-specific - Cellular respiration" "Cluster 14: Neurons - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 19 Mitochondria "CAB016244: , HPA014295: " "unprognostic (2.43e-1)" "unprognostic (2.01e-1)" "unprognostic (6.93e-2)" "unprognostic (2.13e-1)" "unprognostic (3.60e-2)" "unprognostic (2.72e-1)" "unprognostic (3.76e-1)" "unprognostic (8.15e-3)" "unprognostic (7.02e-2)" "unprognostic (2.46e-2)" "unprognostic (1.09e-2)" "unprognostic (4.54e-3)" "unprognostic (7.44e-2)" "unprognostic (5.56e-3)" "unprognostic (1.55e-3)" "unprognostic (9.83e-2)" "unprognostic (1.13e-1)" "unprognostic (3.22e-3)" "unprognostic (1.90e-1)" "unprognostic (4.01e-3)" "unprognostic (3.48e-2)" "unprognostic (4.00e-2)" "unprognostic (8.47e-3)" "unprognostic (8.91e-2)" "unprognostic (7.84e-2)" "unprognostic (3.41e-2)" "unprognostic (9.99e-3)" "unprognostic (1.60e-1)" "unprognostic (4.33e-1)" "unprognostic (2.81e-2)" "unprognostic (2.70e-2)" COX7A1 "COX7A, COX7AH" ENSG00000161281 "Cytochrome c oxidase subunit 7A1" P24310 19 36150922-36152449 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 12 "heart muscle: 4516.8;skeletal muscle: 6519.5;tongue: 4622.3" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 173.1;Decidual stromal cells: 269.1;Hepatic stellate cells: 167.8;Late spermatids: 157.2;Leydig cells: 172.0;Lymphatic endothelial cells: 151.1;Pericytes: 158.7;Peritubular myoid cells: 212.4;Smooth muscle cells: 277.7;Thymic myoid cells: 1017.0;Vascular smooth muscle cells: 279.6" "Cell type enhanced" "Detected in all" "pericyte: 98.4;vascular associated smooth muscle cell: 89.0" "Cancer enriched" "Detected in all" 5 "Kidney Chromophobe (TCGA): 760.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "thyroid cancer: 28.2" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 53: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 2 "unprognostic (1.20e-2)" "unprognostic (1.47e-1)" "unprognostic (2.25e-1)" "potential prognostic favorable (7.02e-4)" "unprognostic (2.89e-3)" "unprognostic (2.21e-1)" "unprognostic (2.14e-1)" "unprognostic (2.97e-3)" "unprognostic (2.87e-2)" "unprognostic (3.77e-2)" "validated prognostic favorable (5.85e-4)" "validated prognostic favorable (7.17e-5)" "unprognostic (1.57e-2)" "unprognostic (6.63e-2)" "unprognostic (6.28e-3)" "unprognostic (1.94e-1)" "unprognostic (3.99e-2)" "unprognostic (3.38e-2)" "unprognostic (7.07e-2)" "unprognostic (9.82e-2)" "unprognostic (1.64e-2)" "unprognostic (2.61e-1)" "unprognostic (4.98e-3)" "unprognostic (4.77e-2)" "unprognostic (1.83e-2)" "unprognostic (1.23e-1)" "unprognostic (2.04e-1)" "unprognostic (2.04e-3)" "unprognostic (1.61e-1)" "unprognostic (6.59e-2)" "unprognostic (1.94e-1)" COX7A2 "COX7AL, COXVIIa-L" ENSG00000112695 "Cytochrome c oxidase subunit 7A2" P14406 6 75237675-75250323 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 4290.7;Esophageal apical cells: 2722.4;Late primary spermatocytes: 7450.6;Late spermatids: 4786.3;Parietal cells: 7363.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 380000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 21: Non-specific - Metabolism" "Cluster 28: Non-specific - Nuclear processes" "Cluster 97: Non-specific - Cellular respiration" 11 "unprognostic (5.35e-2)" "unprognostic (1.12e-2)" "unprognostic (7.96e-3)" "unprognostic (2.25e-1)" "unprognostic (2.48e-3)" "unprognostic (1.69e-1)" "unprognostic (2.40e-1)" "unprognostic (2.98e-1)" "unprognostic (1.94e-2)" "potential prognostic unfavorable (1.16e-4)" "unprognostic (1.34e-1)" "unprognostic (4.78e-2)" "unprognostic (3.28e-2)" "unprognostic (1.13e-1)" "potential prognostic unfavorable (8.23e-6)" "unprognostic (2.32e-2)" "unprognostic (5.29e-3)" "unprognostic (1.13e-1)" "unprognostic (1.31e-1)" "unprognostic (1.32e-2)" "unprognostic (1.85e-1)" "unprognostic (2.78e-1)" "unprognostic (1.33e-1)" "unprognostic (1.66e-1)" "unprognostic (2.37e-1)" "unprognostic (4.82e-2)" "unprognostic (1.53e-2)" "unprognostic (2.68e-2)" "unprognostic (1.61e-1)" "unprognostic (2.63e-1)" "unprognostic (1.49e-1)" COX7A2L "COX7AR, COX7RP, EB1, SCAF1, SCAFI, SIG81" ENSG00000115944 "Cytochrome c oxidase subunit 7A2 like" O14548 2 42333546-42425088 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 805.9;Parietal cells: 735.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059124, CAB073545" Enhanced Nucleoli,Mitochondria NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 25: Non-specific - Ribosome" "Cluster 97: Non-specific - Cellular respiration" 7 Mitochondria Nucleoli "CAB073545: , HPA059124: " "unprognostic (2.12e-2)" "unprognostic (1.98e-3)" "unprognostic (2.84e-3)" "unprognostic (1.21e-1)" "unprognostic (2.37e-2)" "unprognostic (8.51e-2)" "unprognostic (1.32e-1)" "unprognostic (3.42e-1)" "potential prognostic unfavorable (4.87e-4)" "unprognostic (1.10e-1)" "potential prognostic favorable (1.75e-8)" "unprognostic (4.38e-2)" "unprognostic (4.40e-3)" "validated prognostic unfavorable (4.91e-5)" "validated prognostic unfavorable (2.85e-4)" "unprognostic (1.43e-1)" "unprognostic (1.05e-1)" "unprognostic (3.81e-2)" "unprognostic (1.20e-1)" "unprognostic (7.79e-2)" "unprognostic (3.99e-2)" "unprognostic (1.67e-1)" "unprognostic (1.39e-1)" "unprognostic (3.10e-2)" "unprognostic (1.23e-2)" "unprognostic (3.73e-2)" "unprognostic (2.77e-1)" "unprognostic (5.17e-2)" "unprognostic (2.86e-1)" "unprognostic (1.91e-2)" "unprognostic (1.28e-1)" COX7B ENSG00000131174 "Cytochrome c oxidase subunit 7B" P24311 X 77899440-77907376 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1007.2;skeletal muscle: 1052.7" "Cell type enhanced" "Detected in many" "Colonocytes: 1436.6;Enterocytes: 1271.6;Esophageal apical cells: 2135.9;Esophageal basal cells: 1257.4;Esophageal suprabasal cells: 1961.9;Hepatocytes: 1307.7;Parietal cells: 4891.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" HPA058041 Uncertain NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 97: Non-specific - Cellular respiration" 3 "HPA058041: " "unprognostic (1.10e-1)" "potential prognostic unfavorable (2.68e-4)" "unprognostic (1.48e-1)" "potential prognostic favorable (2.58e-5)" "unprognostic (1.72e-1)" "unprognostic (1.47e-1)" "unprognostic (1.63e-1)" "unprognostic (1.12e-1)" "unprognostic (1.80e-2)" "unprognostic (1.73e-2)" "unprognostic (1.74e-1)" "unprognostic (6.20e-3)" "unprognostic (7.59e-2)" "unprognostic (2.34e-1)" "unprognostic (9.24e-3)" "unprognostic (4.78e-2)" "unprognostic (1.02e-1)" "unprognostic (1.95e-2)" "unprognostic (4.64e-2)" "unprognostic (2.28e-1)" "unprognostic (7.69e-2)" "unprognostic (3.20e-1)" "unprognostic (2.79e-1)" "unprognostic (1.15e-1)" "unprognostic (1.71e-1)" "unprognostic (2.57e-1)" "unprognostic (2.85e-2)" "unprognostic (6.84e-2)" "unprognostic (2.12e-1)" "unprognostic (1.30e-1)" "unprognostic (8.75e-2)" COX7B2 ENSG00000170516 "Cytochrome c oxidase subunit 7B2" Q8TF08 4 46734827-46909245 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 69 "testis: 79.9" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 70.3;Early primary spermatocytes: 221.5;Early spermatids: 424.5;Late primary spermatocytes: 1075.3;Late spermatids: 234.1;Undifferentiated spermatogonia: 77.4" "Cell type enriched" "Detected in some" 5 "Bergmann glia: 9.4" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 17.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 15.3;thyroid cancer: 17.8" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" "unprognostic (3.31e-2)" "unprognostic (4.06e-1)" "unprognostic (1.25e-1)" "unprognostic (2.20e-2)" "unprognostic (2.76e-1)" "unprognostic (4.00e-2)" "unprognostic (8.38e-2)" "unprognostic (6.45e-3)" "unprognostic (1.78e-1)" "unprognostic (1.07e-1)" "unprognostic (2.73e-1)" COX7C ENSG00000127184 "Cytochrome c oxidase subunit 7C" P15954 5 86617928-86620962 "Metabolic proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 2234.1" "Cell type enhanced" "Detected in all" "Hepatocytes: 2969.4;Parietal cells: 7697.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046647 Approved NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 97: Non-specific - Cellular respiration" 11 "HPA046647: " "unprognostic (1.67e-1)" "unprognostic (2.83e-1)" "unprognostic (5.24e-2)" "unprognostic (8.74e-2)" "unprognostic (5.90e-3)" "unprognostic (6.36e-2)" "unprognostic (1.03e-2)" "unprognostic (3.18e-1)" "unprognostic (1.85e-2)" "unprognostic (2.57e-2)" "potential prognostic favorable (5.02e-5)" "unprognostic (3.10e-1)" "unprognostic (4.86e-2)" "unprognostic (1.35e-1)" "unprognostic (2.93e-3)" "unprognostic (3.45e-2)" "unprognostic (6.41e-2)" "unprognostic (3.50e-1)" "unprognostic (2.14e-1)" "unprognostic (1.36e-1)" "unprognostic (1.61e-3)" "unprognostic (2.82e-2)" "unprognostic (1.18e-1)" "unprognostic (6.90e-2)" "unprognostic (2.38e-1)" "unprognostic (1.08e-1)" "unprognostic (3.60e-1)" "unprognostic (3.95e-2)" "unprognostic (2.38e-1)" "unprognostic (1.21e-1)" "unprognostic (2.52e-1)" COX8A "COX, COX8, COX8-2, COX8L, VIII, VIII-L" ENSG00000176340 "Cytochrome c oxidase subunit 8A" P10176 11 63974620-63976543 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Parietal cells: 1695.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055942 Supported NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 24: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 9 "HPA055942: " "unprognostic (1.56e-1)" "unprognostic (2.60e-2)" "unprognostic (3.29e-1)" "potential prognostic favorable (2.36e-4)" "unprognostic (9.38e-2)" "unprognostic (3.23e-1)" "unprognostic (1.47e-1)" "unprognostic (7.80e-2)" "unprognostic (2.64e-3)" "unprognostic (1.76e-2)" "unprognostic (2.12e-3)" "unprognostic (3.63e-2)" "unprognostic (1.11e-3)" "unprognostic (1.32e-2)" "potential prognostic unfavorable (9.13e-6)" "potential prognostic unfavorable (4.43e-4)" "unprognostic (5.24e-2)" "unprognostic (3.42e-2)" "unprognostic (3.72e-1)" "unprognostic (2.33e-3)" "unprognostic (4.78e-1)" "unprognostic (1.06e-1)" "unprognostic (6.72e-2)" "unprognostic (4.52e-2)" "unprognostic (4.92e-2)" "unprognostic (2.22e-1)" "unprognostic (2.29e-1)" "unprognostic (6.95e-2)" "unprognostic (5.09e-2)" "unprognostic (3.91e-1)" "unprognostic (6.09e-2)" COX8C COX8-3 ENSG00000187581 "Cytochrome c oxidase subunit 8C" Q7Z4L0 14 93347182-93348356 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 189 "testis: 71.9" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 50.2;Early primary spermatocytes: 175.1;Early spermatids: 327.9;Late primary spermatocytes: 192.1;Late spermatids: 865.5;Oocytes: 96.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "Lung Squamous Cell Carcinoma (TCGA): 1.1;Ovary Serous Cystadenocarcinoma (TCGA): 3.6;Testicular Germ Cell Tumor (TCGA): 4.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA003127 Approved NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" "HPA003127: " "unprognostic (4.56e-3)" "unprognostic (3.81e-1)" "unprognostic (9.56e-2)" "unprognostic (2.80e-1)" CP AB073614 ENSG00000047457 Ceruloplasmin P00450 3 149162410-149221829 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" Oxidoreductase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 1750.2" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 346.6;Conjunctival goblet cells: 648.5;Endometrial glandular cells: 522.0;Endometrial luminal cells: 398.1;Endometrial secretory cells: 590.8;Hepatocytes: 1510.9;Lacrimal acinar cells: 473.7;Müller glia: 757.2;Pancreatic acinar cells: 445.8;Pituicytes/FSCs: 898.5;Prostatic club cells: 369.6;Respiratory deuterosomal cells: 472.7;Respiratory secretory cells: 438.6;Submucosal glandular cells: 432.2" "Group enriched" "Detected in all" 6 "choroid plexus epithelial cell: 361.5;ependymal cell: 209.6" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 299.2" "Region enriched" "Detected in all" 5 "choroid plexus: 227.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 49.6;ovarian cancer: 45.2;Rhabdoid: 37.2" "Liver - Hepatocytes, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001834, CAB008591" Supported "Secreted to blood" Enzyme NA NA 160000000000 240000000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 36: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 11 "CAB008591: , HPA001834: " "unprognostic (7.95e-2)" "unprognostic (2.42e-1)" "unprognostic (5.24e-3)" "unprognostic (1.54e-1)" "unprognostic (2.71e-1)" "unprognostic (7.99e-2)" "unprognostic (2.46e-2)" "unprognostic (2.00e-1)" "unprognostic (1.42e-2)" "unprognostic (1.44e-2)" "unprognostic (1.20e-1)" "unprognostic (1.26e-1)" "unprognostic (1.19e-1)" "unprognostic (5.40e-2)" "unprognostic (2.39e-2)" "potential prognostic unfavorable (6.17e-4)" "unprognostic (2.89e-2)" "unprognostic (4.26e-2)" "unprognostic (1.58e-1)" "unprognostic (4.90e-3)" "unprognostic (1.09e-1)" "unprognostic (1.60e-3)" "unprognostic (2.98e-1)" "unprognostic (8.24e-2)" "unprognostic (2.71e-1)" "unprognostic (7.93e-3)" "unprognostic (1.12e-1)" "unprognostic (1.60e-1)" "unprognostic (1.32e-2)" CPA1 CPA ENSG00000091704 "Carboxypeptidase A1" P15085 7 130380339-130388114 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5428 "pancreas: 223994.4" "Cell type enriched" "Detected in some" 200 "Pancreatic acinar cells: 51967.9" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 726 "Pancreatic Adenocarcinoma (TCGA): 3662.4" "Region enhanced" "Detected in single" "choroid plexus: 2.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 1.1;Sarcoma: 1.2;Uterine cancer: 1.1" "Pancreas - Exocrine glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA021836, CAB025197, HPA052215" Enhanced "Secreted to digestive system" Enzyme NA NA 7900000 "Cluster 8: Pancreas - Proteolysis" "Cluster 23: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 5: Pancreatic acinar cells - Pancreatic exocrine secretion" "CAB025197: , HPA021836: , HPA052215: " "unprognostic (3.84e-1)" "unprognostic (2.10e-1)" "unprognostic (2.85e-2)" "unprognostic (1.24e-2)" "unprognostic (1.85e-1)" CPA2 ENSG00000158516 "Carboxypeptidase A2" P48052 7 130266863-130289798 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 417 "pancreas: 42780.5" "Cell type enriched" "Detected in some" 32 "Pancreatic acinar cells: 23034.3" "Cell type enriched" "Detected in some" 5 "oligodendrocyte: 6.8" "Cancer enriched" "Detected in many" 48 "Pancreatic Adenocarcinoma (TCGA): 713.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 2.2" "Pancreas - Exocrine glandular cells, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA020342, HPA021317" Enhanced Approved "Golgi apparatus" "Secreted to digestive system" Enzyme NA NA 810000 "Cluster 8: Pancreas - Proteolysis" "Cluster 30: White matter - Myelination" "Cluster 66: Non-specific - Mitochondria" "Cluster 5: Pancreatic acinar cells - Pancreatic exocrine secretion" 1 "Golgi apparatus" "HPA020342: , HPA021317: " "unprognostic (1.75e-2)" "unprognostic (3.04e-2)" "unprognostic (1.82e-1)" "unprognostic (2.01e-1)" "potential prognostic unfavorable (8.49e-4)" "unprognostic (8.09e-2)" "unprognostic (1.51e-1)" "unprognostic (1.39e-1)" CPA3 ENSG00000163751 "Carboxypeptidase A3" P15088 3 148865296-148897203 "Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 104.9;lung: 81.4" "Cell type enriched" "Detected in some" 23 "Mast cells: 3888.8" "Cell type enhanced" "Detected in single" "leukocyte: 1.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 1540 "basophil: 1120.0" "Lineage enriched" "Detected in single" 5543 "granulocytes: 1120.0" "Cancer enriched" "Detected in some" 12 "Leukemia: 15.3" "Adipose subcutaneous - Mast cells, Adipose visceral - Mast cells, Colon - Mast cells, Lung - Mast cells, Minor Salivary Gland - Mast cells, Prostate - Fibroblasts, Skeletal muscle - Macrophages, Skin - Mast cells" "Not detected" "Not detected" "HPA006479, HPA008689, CAB020712" Enhanced Approved "Nucleoplasm,Golgi apparatus" "Secreted to blood" Enzyme NA NA 7520000 1400000 "Cluster 46: Basophils - Proteolysis" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 47: Leukemia - Hemostasis" "Cluster 58: Mast cells - Allergic inflammatory responses" 1 "Golgi apparatus" Nucleoplasm "CAB020712: , HPA006479: , HPA008689: " "unprognostic (1.33e-1)" "unprognostic (1.78e-1)" "unprognostic (1.58e-1)" "unprognostic (2.00e-2)" "unprognostic (2.69e-2)" "unprognostic (4.34e-2)" "unprognostic (2.20e-1)" "unprognostic (4.86e-3)" "unprognostic (1.93e-1)" "validated prognostic favorable (1.10e-6)" "validated prognostic favorable (2.92e-4)" "unprognostic (1.13e-1)" "unprognostic (1.03e-1)" "unprognostic (9.31e-2)" "unprognostic (1.03e-3)" "unprognostic (1.47e-1)" "unprognostic (7.50e-2)" "unprognostic (1.93e-1)" "unprognostic (2.07e-1)" "unprognostic (2.49e-1)" "unprognostic (4.56e-2)" "unprognostic (4.79e-2)" "unprognostic (5.03e-3)" "unprognostic (2.60e-1)" "unprognostic (4.34e-3)" "unprognostic (1.76e-1)" "unprognostic (1.94e-2)" CPA4 CPA3 ENSG00000128510 "Carboxypeptidase A4" Q9UI42 7 130293134-130324180 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 21.0;skin 1: 53.9" "Group enriched" "Detected in some" 4 "Esophageal apical cells: 295.1;Salivary duct cells: 382.0" "Cell type enhanced" "Detected in some" "amygdala excitatory: 1.9;mammillary body: 2.0;oligodendrocyte: 2.1" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 25.2;Head and Neck Squamous Cell Carcinoma (TCGA): 19.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 157.9" "Adipose visceral - Mesothelial cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA021030 Approved "Nucleoplasm,Plasma membrane,Centriolar satellite" "Secreted in other tissues" Enzyme NA Yes 360000 "Cluster 58: Skin - Keratinization" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 84: Apical squamous epithelium - Cornification" 17 "Nucleoplasm, Plasma membrane" "Centriolar satellite" "HPA021030: " "unprognostic (5.50e-3)" "unprognostic (8.77e-3)" "unprognostic (3.10e-1)" "unprognostic (4.81e-2)" "potential prognostic unfavorable (4.24e-4)" "unprognostic (3.10e-2)" "unprognostic (5.47e-2)" "validated prognostic unfavorable (2.63e-7)" "validated prognostic unfavorable (3.14e-6)" "unprognostic (6.45e-2)" "unprognostic (2.81e-1)" "unprognostic (1.28e-1)" "unprognostic (1.40e-1)" "unprognostic (7.78e-2)" "unprognostic (1.17e-2)" "potential prognostic unfavorable (5.25e-5)" "unprognostic (1.66e-1)" "unprognostic (6.34e-3)" CPA5 ENSG00000158525 "Carboxypeptidase A5" Q8WXQ8 7 130344816-130368730 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "testis: 30.4" "Cell type enriched" "Detected in some" 4 "Late spermatids: 258.1" "Cell type enhanced" "Detected in single" "mammillary body: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "memory CD4 T-cell: 16.9;naive CD8 T-cell: 42.6;T-reg: 56.6" "Lineage enriched" "Detected in single" 101 "T-cells: 56.6" "Cancer enriched" "Detected in some" 26 "Sarcoma: 27.2" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA020322 Approved Nucleoplasm "Secreted in male reproductive system" Enzyme NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 39: Testis - Nuclear processes" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" Nucleoplasm "HPA020322: " CPA6 CPAH ENSG00000165078 "Carboxypeptidase A6" Q8N4T0 8 67422038-67746378 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 2.2;prostate: 2.6;retina: 2.1" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 683.9;Colonocytes: 228.4;Enteric stem cells: 263.0;Enteric transient amplifying cells: 207.6;Müller glia: 503.4;Prostatic club cells: 937.5;Prostatic hillock cells: 1177.7;Urothelial cells: 143.2" "Group enriched" "Detected in many" 4 "central nervous system macrophage: 101.8;midbrain-derived inhibitory: 94.1" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 1.5;liver cancer: 1.9" "Skin - Hair cortex cells, Skin - Inner root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in some" 9 "olfactory bulb: 12.6" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" Enzyme NA NA "Cluster 42: Retina - Visual perception" "Cluster 72: Neuronal - Signal transduction" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" "unprognostic (4.34e-2)" "unprognostic (9.18e-2)" "unprognostic (2.16e-2)" "unprognostic (1.54e-2)" "unprognostic (1.91e-1)" "unprognostic (1.76e-1)" "unprognostic (7.20e-2)" "unprognostic (8.52e-2)" "unprognostic (4.31e-2)" "unprognostic (6.44e-2)" "unprognostic (1.23e-1)" "unprognostic (2.99e-1)" CPAMD8 "K-CAP, KIAA1283, VIP" ENSG00000160111 "C3 and PZP like alpha-2-macroglobulin domain containing 8" Q8IZJ3 19 16892951-17026815 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 34.6" "Cell type enhanced" "Detected in many" "Adipocytes: 62.8;Adrenal medulla cells: 74.5;Astrocytes: 75.0;Basal prostatic cells: 101.6;Epididymal principal cells: 119.8;Leydig cells: 98.9;Ocular epithelial cells: 198.5;Prostatic glandular cells: 137.6;Renal collecting duct intercalated cells: 120.7;Renal collecting duct principal cells: 120.0;Retinal amacrine cells: 84.7;Transitional alveolar cells: 64.1" "Cell type enriched" "Detected in many" 7 "astrocyte: 206.5" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 34.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 6.2" "Adrenal gland - Adrenal medulla cells, Minor Salivary Gland - Adipocytes (Minor salivary gland)" "Region enriched" "Detected in single" 7 "spinal cord: 5.5" "HPA031327, HPA031328, HPA031329, HPA031330" Uncertain Uncertain "Focal adhesion sites" "Secreted to blood" "Enzyme inhibitor" NA NA 200000 "Cluster 22: Epididymis - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" "Focal adhesion sites" "HPA031327: , HPA031328: , HPA031329: , HPA031330: " "unprognostic (1.26e-1)" "unprognostic (1.12e-1)" "unprognostic (1.16e-1)" "unprognostic (1.25e-1)" "unprognostic (1.92e-1)" "unprognostic (8.17e-3)" "unprognostic (2.89e-3)" "unprognostic (1.40e-1)" "unprognostic (3.41e-3)" "unprognostic (1.11e-1)" "unprognostic (1.44e-2)" "unprognostic (3.40e-1)" "unprognostic (3.63e-3)" "unprognostic (6.80e-2)" "potential prognostic unfavorable (6.69e-4)" "unprognostic (1.89e-1)" "unprognostic (5.28e-2)" "unprognostic (5.89e-2)" "unprognostic (1.49e-1)" CPB1 ENSG00000153002 "Carboxypeptidase B1" P15086 3 148791102-148860187 "Enzymes, Plasma proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 2700 "pancreas: 213987.3" "Cell type enriched" "Detected in some" 102 "Pancreatic acinar cells: 35500.0" "Cell type enhanced" "Detected in some" "committed oligodendrocyte precursor: 12.0;oligodendrocyte: 39.8" "Group enriched" "Detected in some" 294 "Breast Invasive Carcinoma (TCGA): 2086.8;Pancreatic Adenocarcinoma (TCGA): 3154.8" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 4.0" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in single" 15 "Rhabdoid: 14.4" "Pancreas - Exocrine glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB026158, HPA038069, HPA046340" Enhanced Approved "Endoplasmic reticulum" "Secreted to digestive system" Enzyme NA NA 5000000 "Cluster 20: Non-specific - DNA binding" "Cluster 8: Pancreas - Proteolysis" "Cluster 11: White matter - Signal transduction" "Cluster 5: Rhabdoid - Unknown function" "Cluster 5: Pancreatic acinar cells - Pancreatic exocrine secretion" 1 "Endoplasmic reticulum" "CAB026158: , HPA038069: , HPA046340: " "unprognostic (1.80e-2)" "unprognostic (2.80e-2)" "unprognostic (3.60e-3)" "unprognostic (3.07e-2)" "unprognostic (1.19e-2)" "unprognostic (9.72e-2)" "unprognostic (2.62e-1)" CPB2 "CPU, PCPB, TAFI" ENSG00000080618 "Carboxypeptidase B2" Q96IY4 13 46053186-46105033 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 84 "liver: 1387.2" "Cell type enriched" "Detected in many" 7 "Hepatocytes: 1723.9" "Cell type enhanced" "Detected in many" "oligodendrocyte: 87.4" "Cancer enriched" "Detected in some" 57 "Liver Hepatocellular Carcinoma (TCGA): 350.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "liver cancer: 11.2" "Liver - Hepatocytes, Lung - Alveolar cells type 2" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA004146 Approved "Secreted to blood" "Blood coagulation" NA NA 4300000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" "HPA004146: " "unprognostic (1.22e-1)" "potential prognostic favorable (2.55e-4)" "unprognostic (2.42e-3)" "unprognostic (1.94e-2)" "unprognostic (7.95e-2)" "unprognostic (3.87e-1)" "unprognostic (5.07e-3)" "unprognostic (6.85e-2)" CPD GP180 ENSG00000108582 "Carboxypeptidase D" O75976 17 30378927-30469989 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 9 "Neutrophils: 3285.9" "Cell type enhanced" "Detected in all" "endothelial cell: 443.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 25.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052796 Approved Approved Nucleoli,Cytosol NA NA 1200000 "Cluster 35: Neutrophils - Protein binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 29 Cytosol Nucleoli "HPA052796: " "unprognostic (7.00e-2)" "unprognostic (1.84e-1)" "unprognostic (7.16e-2)" "unprognostic (2.43e-2)" "unprognostic (9.13e-3)" "unprognostic (3.83e-2)" "unprognostic (9.90e-3)" "unprognostic (2.21e-3)" "unprognostic (1.05e-2)" "unprognostic (7.92e-3)" "unprognostic (2.22e-3)" "unprognostic (1.92e-2)" "unprognostic (1.26e-1)" "unprognostic (2.71e-3)" "unprognostic (2.72e-3)" "unprognostic (4.89e-2)" "potential prognostic unfavorable (6.88e-4)" "unprognostic (1.97e-2)" "unprognostic (1.39e-1)" "unprognostic (2.00e-1)" "unprognostic (1.12e-2)" "unprognostic (8.12e-2)" "unprognostic (2.68e-1)" "unprognostic (1.54e-1)" "unprognostic (1.70e-1)" "unprognostic (1.60e-1)" "unprognostic (2.64e-2)" "unprognostic (2.95e-2)" "unprognostic (2.41e-1)" "unprognostic (1.40e-1)" "unprognostic (1.90e-1)" CPE ENSG00000109472 "Carboxypeptidase E" P16870 4 165361194-165498547 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Disease variant, Hypogonadotropic hypogonadism, Intellectual disability, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1047.2;retina: 687.1" "Cell type enhanced" "Detected in many" "Astrocytes: 1098.3;Bergmann glia: 1119.3;Cone photoreceptor cells: 952.3;Corticotrophs: 711.1;Lactotrophs: 1539.0;Pancreatic islet cells: 2923.3;Prostatic glandular cells: 1636.6;Somatotrophs: 2673.1;Thyrotrophs: 737.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 556.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "testis cancer: 315.7;thyroid cancer: 400.8" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Kidney - Fibroblasts, Prostate - Prostate glandular cells, Skeletal muscle - Fibroblasts, Spleen - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003819, CAB024907, CAB080183" Supported Approved Vesicles,Centrosome "Intracellular and membrane" Enzyme NA NA 390000 "Cluster 73: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 2 "Vesicles, Centrosome" "CAB024907: , CAB080183: , HPA003819: " "unprognostic (5.44e-3)" "unprognostic (4.28e-2)" "unprognostic (2.18e-1)" "potential prognostic unfavorable (6.62e-4)" "unprognostic (3.75e-1)" "unprognostic (1.14e-1)" "unprognostic (2.50e-1)" "unprognostic (2.69e-1)" "unprognostic (2.30e-2)" "unprognostic (5.48e-3)" "unprognostic (4.57e-3)" "unprognostic (1.94e-2)" "unprognostic (1.83e-1)" "unprognostic (7.71e-2)" "unprognostic (1.12e-1)" "unprognostic (3.20e-2)" "unprognostic (2.29e-1)" "unprognostic (4.91e-2)" "unprognostic (2.24e-2)" "unprognostic (7.84e-3)" "potential prognostic unfavorable (9.50e-4)" "unprognostic (6.74e-3)" "unprognostic (1.64e-1)" "unprognostic (3.14e-2)" "unprognostic (1.31e-1)" "unprognostic (7.85e-2)" "unprognostic (3.75e-3)" "unprognostic (4.89e-3)" "unprognostic (1.68e-1)" "unprognostic (4.24e-2)" "unprognostic (1.04e-1)" CPEB1 "CPEB, FLJ13203" ENSG00000214575 "Cytoplasmic polyadenylation element binding protein 1" Q9BZB8 15 82543201-82648861 "Predicted intracellular proteins" "mRNA processing, Translation regulation" "Activator, Repressor, Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 31.6;testis: 30.4" "Cell type enhanced" "Detected in some" "Astrocytes: 24.9;Brain excitatory neurons: 27.7;Brain inhibitory neurons: 21.7;Choroid plexus epithelial cells: 102.3;Ependymal cells: 68.5;Late spermatids: 22.4;Oligodendrocytes: 156.8;Other brain neurons: 39.5;Podocytes: 44.7" "Cell type enhanced" "Detected in all" "oligodendrocyte: 238.9" "Cancer enriched" "Detected in many" 7 "Testicular Germ Cell Tumor (TCGA): 61.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD8 T-cell: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Testis - Spermatogonia, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040396 Supported Nucleoplasm,Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 80: Oligodendrocytes - Myelination" 13 "Nucleoplasm, Cytosol" "HPA040396: " "unprognostic (2.43e-1)" "unprognostic (5.32e-3)" "unprognostic (2.22e-1)" "unprognostic (3.58e-1)" "potential prognostic unfavorable (6.65e-6)" "unprognostic (6.13e-3)" "unprognostic (4.08e-1)" "unprognostic (5.88e-2)" "unprognostic (1.47e-1)" "unprognostic (2.37e-1)" "unprognostic (3.24e-3)" "unprognostic (8.15e-2)" "unprognostic (3.88e-2)" "unprognostic (1.31e-1)" "unprognostic (6.72e-3)" "unprognostic (7.52e-2)" "unprognostic (1.73e-1)" CPEB2 ENSG00000137449 "Cytoplasmic polyadenylation element binding protein 2" Q7Z5Q1 4 15002481-15070153 "Predicted intracellular proteins" "Translation regulation" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 369.5;Melanocytes: 436.8;Neutrophil progenitors: 260.3;Neutrophils: 369.3;Ocular epithelial cells: 277.4;Oligodendrocytes: 397.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072513 Approved Cytosol Yes No "Cluster 35: Neutrophils - Protein binding" "Cluster 47: Testis - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 15: Kidney cancer - Membrane components" "Cluster 100: Stratified epithelial cells - Barrier functions" 2 Cytosol "HPA072513: " "unprognostic (1.06e-1)" "unprognostic (8.97e-2)" "unprognostic (2.52e-1)" "potential prognostic unfavorable (8.00e-5)" "unprognostic (1.23e-1)" "unprognostic (3.13e-2)" "unprognostic (1.72e-1)" "potential prognostic unfavorable (3.37e-4)" "unprognostic (8.06e-2)" "unprognostic (5.67e-2)" "unprognostic (5.50e-3)" "unprognostic (9.77e-2)" "unprognostic (4.96e-2)" "unprognostic (6.96e-3)" "unprognostic (2.06e-2)" "unprognostic (1.83e-2)" "unprognostic (2.35e-1)" "unprognostic (1.40e-1)" "unprognostic (4.29e-1)" "unprognostic (1.32e-1)" "unprognostic (4.56e-2)" "unprognostic (1.43e-2)" "unprognostic (1.26e-1)" "unprognostic (1.13e-1)" "unprognostic (2.32e-1)" "unprognostic (1.20e-1)" "unprognostic (3.17e-1)" "unprognostic (1.20e-1)" "unprognostic (1.63e-1)" "unprognostic (4.48e-2)" "unprognostic (5.91e-2)" CPEB3 KIAA0940 ENSG00000107864 "Cytoplasmic polyadenylation element binding protein 3" Q8NE35 10 92046692-92291078 "Predicted intracellular proteins" "Translation regulation" "Activator, Repressor, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 30.1" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 660.5;Late spermatids: 710.3;Retinal ganglion cells: 648.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.6" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Myeloma: 4.5" "Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Skin - Eccrine sweat gland cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070942 Approved "Nucleoplasm,Plasma membrane,Midbody,Cytosol" Yes No "Cluster 42: Non-specific - Vesicular transport" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 1 Cytosol "Nucleoplasm, Plasma membrane, Midbody" "HPA070942: " "potential prognostic favorable (6.76e-4)" "unprognostic (1.80e-1)" "unprognostic (2.72e-1)" "unprognostic (5.22e-2)" "unprognostic (1.99e-1)" "potential prognostic unfavorable (8.27e-4)" "unprognostic (1.27e-1)" "potential prognostic favorable (9.86e-4)" "potential prognostic favorable (1.94e-4)" "unprognostic (5.92e-2)" "validated prognostic favorable (3.41e-5)" "validated prognostic favorable (3.44e-4)" "unprognostic (3.74e-3)" "validated prognostic favorable (3.16e-4)" "validated prognostic favorable (2.64e-6)" "unprognostic (3.47e-3)" "unprognostic (1.75e-2)" "unprognostic (4.80e-2)" "unprognostic (8.68e-2)" "unprognostic (3.97e-2)" "unprognostic (8.85e-2)" "unprognostic (3.39e-2)" "unprognostic (5.66e-2)" "unprognostic (2.50e-1)" "unprognostic (1.48e-1)" "unprognostic (1.20e-1)" "unprognostic (4.66e-2)" "unprognostic (6.69e-3)" "unprognostic (2.25e-1)" CPEB4 KIAA1673 ENSG00000113742 "Cytoplasmic polyadenylation element binding protein 4" Q17RY0 5 173888349-173961980 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adrenal cortex cells: 1333.5;Choroid plexus epithelial cells: 890.8;Distal convoluted tubule cells: 1600.3;Neutrophils: 1243.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 57.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 5.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038394 Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 31: Non-specific - Transcription" "Cluster 47: Leukemia - Hemostasis" "Cluster 18: Adrenal cortex cells - Steroidogensis" 4 "Nucleoplasm, Golgi apparatus" Vesicles "HPA038394: " "unprognostic (8.84e-3)" "unprognostic (6.52e-2)" "unprognostic (1.37e-1)" "unprognostic (1.13e-2)" "unprognostic (1.38e-1)" "unprognostic (1.75e-1)" "unprognostic (1.04e-1)" "unprognostic (3.09e-2)" "unprognostic (1.03e-1)" "unprognostic (2.71e-2)" "potential prognostic favorable (1.20e-8)" "unprognostic (6.41e-3)" "unprognostic (6.43e-2)" "unprognostic (3.21e-1)" "unprognostic (9.75e-3)" "unprognostic (3.39e-2)" "unprognostic (1.86e-1)" "unprognostic (1.99e-2)" "unprognostic (9.49e-2)" "unprognostic (1.73e-1)" "potential prognostic unfavorable (2.71e-6)" "unprognostic (1.94e-1)" "unprognostic (1.99e-2)" "unprognostic (2.20e-1)" "unprognostic (1.15e-1)" "unprognostic (6.51e-2)" "unprognostic (1.52e-1)" "unprognostic (5.63e-2)" "unprognostic (5.14e-2)" "unprognostic (9.46e-3)" "unprognostic (2.69e-1)" CPED1 "C7orf58, FLJ21986" ENSG00000106034 "Cadherin like and PC-esterase domain containing 1" A4D0V7 7 120988697-121297442 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Microglia: 752.7;Myonuclei: 2841.2" "Group enriched" "Detected in many" 5 "central nervous system macrophage: 979.4;fibroblast: 554.3;vascular associated smooth muscle cell: 352.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 10.8;intermediate monocyte: 11.4;myeloid DC: 25.2;non-classical monocyte: 7.6;plasmacytoid DC: 15.1" "Group enriched" "Detected in many" 9 "dendritic cells: 25.2;monocytes: 11.4" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Minor Salivary Gland - Fibroblasts, Pancreas - Fibroblasts, Pituitary gland - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012058 Uncertain Approved Nucleoplasm NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" Nucleoplasm "HPA012058: " "unprognostic (4.51e-3)" "unprognostic (9.98e-2)" "unprognostic (1.54e-1)" "unprognostic (2.30e-1)" "unprognostic (9.77e-2)" "unprognostic (3.87e-1)" "unprognostic (1.37e-1)" "unprognostic (8.18e-2)" "unprognostic (1.80e-2)" "unprognostic (1.11e-3)" "unprognostic (1.99e-3)" "unprognostic (3.04e-2)" "unprognostic (1.23e-2)" "potential prognostic favorable (2.90e-4)" "unprognostic (1.94e-1)" "unprognostic (3.36e-2)" "unprognostic (1.35e-1)" "unprognostic (1.11e-1)" "unprognostic (2.17e-2)" "unprognostic (2.14e-1)" "unprognostic (8.66e-2)" "unprognostic (2.46e-1)" "unprognostic (3.43e-2)" "unprognostic (8.71e-3)" "unprognostic (3.02e-2)" "unprognostic (9.60e-3)" "unprognostic (1.06e-1)" "unprognostic (1.65e-1)" "unprognostic (1.26e-1)" CPHXL ENSG00000283755 "Cytoplasmic polyadenylated homeobox like" A0A1W2PPM1 16 75714131-75726490 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Adipocytes: 6.3;Cardiomyocytes: 10.3;Cone photoreceptor cells: 6.2;Epicardial cells: 13.6;Fibro-adipogenic progenitors: 7.4;Hepatic stellate cells: 6.5;Late primary spermatocytes: 5.7;Müller glia: 6.2;Myonuclei: 6.9;Retinal ganglion cells: 19.3;Retinal horizontal cells: 14.0" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" NA NA "Cluster 53: Neurons - Mixed function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" CPHXL2 ENSG00000284484 "Cytoplasmic polyadenylated homeobox like 2" A0A1W2PPK0 16 75660227-75677009 "Predicted intracellular proteins" DNA-binding "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "Adipocytes: 18.8;Cardiomyocytes: 30.9;Epicardial cells: 13.6;Fibro-adipogenic progenitors: 11.9;Myonuclei: 12.0" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" CPLANE1 "C5orf42, FLJ13231, Hug, JBTS17" ENSG00000197603 "Ciliogenesis and planar polarity effector complex subunit 1" Q9H799 5 37106228-37249376 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Respiratory ciliated cells: 349.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036775, HPA036776" Approved Approved "Cytosol,Mid piece,Principal piece" NA NA "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 29: Non-specific - Unknown function" "Cluster 107: Ciliated cells - Cilia assembly & function" "Cytosol, Mid piece, Principal piece" "HPA036775: , HPA036776: " "unprognostic (9.80e-2)" "unprognostic (7.13e-2)" "unprognostic (3.15e-2)" "unprognostic (2.05e-2)" "unprognostic (2.94e-1)" "unprognostic (1.83e-1)" "unprognostic (2.10e-2)" "potential prognostic unfavorable (2.21e-4)" "potential prognostic favorable (1.35e-5)" "unprognostic (1.86e-2)" "unprognostic (4.55e-2)" "unprognostic (5.02e-2)" "unprognostic (2.06e-2)" "unprognostic (1.08e-1)" "unprognostic (1.85e-1)" "unprognostic (2.74e-1)" "unprognostic (3.35e-2)" "unprognostic (1.34e-1)" "potential prognostic unfavorable (1.73e-4)" "unprognostic (5.18e-2)" "unprognostic (1.22e-1)" "unprognostic (2.26e-1)" "unprognostic (2.65e-2)" "unprognostic (4.13e-1)" "unprognostic (1.26e-2)" "unprognostic (2.56e-2)" CPLANE2 "C1orf89, MGC10731, RSG1" ENSG00000132881 "Ciliogenesis and planar polarity effector complex subunit 2" Q9BU20 1 16231692-16237183 "Predicted intracellular proteins" "Cilium biogenesis/degradation, Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Respiratory ciliated cells: 9.8" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028453, HPA041672" Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 78: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 37: Non-specific - mRNA processing" "Cluster 107: Ciliated cells - Cilia assembly & function" 8 Nucleoplasm "Nuclear bodies, Cytosol" "HPA028453: , HPA041672: " "unprognostic (1.44e-2)" "unprognostic (2.18e-2)" "unprognostic (6.55e-2)" "unprognostic (6.03e-2)" "unprognostic (5.07e-2)" "unprognostic (4.47e-2)" "unprognostic (2.96e-2)" "unprognostic (5.60e-2)" "unprognostic (4.50e-2)" "validated prognostic favorable (6.32e-11)" "validated prognostic favorable (2.56e-4)" "unprognostic (6.45e-3)" "unprognostic (1.12e-2)" "unprognostic (2.54e-1)" "unprognostic (5.28e-2)" "unprognostic (1.06e-2)" "unprognostic (1.05e-1)" "unprognostic (2.01e-1)" "unprognostic (1.88e-1)" "unprognostic (9.90e-2)" "unprognostic (1.17e-2)" "unprognostic (4.49e-2)" "unprognostic (1.70e-2)" "unprognostic (1.48e-1)" "unprognostic (3.54e-1)" "unprognostic (1.72e-1)" "unprognostic (1.73e-1)" "unprognostic (2.51e-1)" "unprognostic (4.25e-2)" CPLX1 CPX-I ENSG00000168993 "Complexin 1" O14810 4 784957-826129 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Exocytosis, Neurotransmitter transport, Transport" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 231.0" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 64.3;Brain inhibitory neurons: 89.1;Differentiating spermatogonia: 37.7;Neuroendocrine cells: 44.7;Other brain neurons: 36.5;Pancreatic islet cells: 37.6;Retinal amacrine cells: 68.1;Retinal bipolar cells: 31.5;Retinal ganglion cells: 150.6;Vascular endothelial cells: 43.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 25.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 27.0" "Kidney - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA071191, HPA074390" Supported Uncertain Vesicles NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 4 Vesicles "HPA071191: , HPA074390: " "unprognostic (8.52e-2)" "unprognostic (2.60e-2)" "unprognostic (2.70e-1)" "potential prognostic unfavorable (2.55e-5)" "unprognostic (1.06e-1)" "unprognostic (4.97e-3)" "unprognostic (5.01e-2)" "unprognostic (1.90e-2)" "unprognostic (1.09e-1)" "unprognostic (1.11e-1)" "unprognostic (1.42e-3)" "unprognostic (1.40e-3)" "unprognostic (2.38e-1)" "unprognostic (5.00e-2)" "unprognostic (6.05e-2)" "unprognostic (5.58e-2)" "unprognostic (1.14e-1)" "unprognostic (1.68e-2)" "unprognostic (1.45e-2)" "unprognostic (3.96e-3)" "unprognostic (6.57e-2)" "unprognostic (5.53e-3)" "unprognostic (4.11e-2)" "unprognostic (2.25e-1)" "unprognostic (2.01e-2)" "unprognostic (3.53e-2)" "unprognostic (1.27e-1)" "unprognostic (5.12e-2)" CPLX2 "CPX-2, DKFZp547D155" ENSG00000145920 "Complexin 2" Q6PUV4 5 175796310-175884021 "Predicted intracellular proteins" "Differentiation, Exocytosis, Mast cell degranulation, Neurogenesis, Neurotransmitter transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 461.7;epididymis: 121.4" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 53.2;Brain excitatory neurons: 109.1;Brain inhibitory neurons: 67.3;Corticotrophs: 82.7;Early spermatids: 48.4;Epididymal principal cells: 95.9;Gonadotrophs: 53.9;Lactotrophs: 74.6;Late spermatids: 131.4;Neuroendocrine cells: 39.1;Other brain neurons: 77.2;Pancreatic islet cells: 122.5;Retinal amacrine cells: 126.0;Retinal horizontal cells: 76.1;Somatotrophs: 80.6;Thyrotrophs: 68.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "lung cancer: 44.8;Neuroblastoma: 66.5" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Stomach - Gastric enteroendocrine cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Parafollicular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA071191, HPA074390" Supported Uncertain Vesicles NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 51: Neurons - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 5 Vesicles "HPA071191: , HPA074390: " "unprognostic (2.45e-2)" "unprognostic (8.09e-2)" "unprognostic (4.22e-2)" "unprognostic (1.37e-1)" "unprognostic (3.91e-2)" "unprognostic (2.55e-2)" "unprognostic (5.13e-2)" "potential prognostic unfavorable (5.52e-6)" "unprognostic (7.37e-2)" "potential prognostic unfavorable (2.09e-4)" "unprognostic (4.23e-3)" "unprognostic (1.20e-1)" "unprognostic (1.03e-1)" "unprognostic (1.91e-1)" "unprognostic (7.09e-2)" "unprognostic (1.22e-2)" "unprognostic (4.80e-1)" "unprognostic (1.26e-1)" "unprognostic (3.05e-1)" "unprognostic (9.89e-2)" "unprognostic (1.16e-1)" CPLX3 CPX-III ENSG00000213578 "Complexin 3" Q8WVH0 15 74826627-74831802 "Predicted intracellular proteins" "Exocytosis, Neurotransmitter transport, Sensory transduction, Transport, Vision" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 69.2;heart muscle: 44.8;lymphoid tissue: 117.6;prostate: 127.2;retina: 91.5" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 2.1;Prostatic glandular cells: 1.5" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 15 "Prostate Adenocarcinoma (TCGA): 20.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "ovarian cancer: 8.9;Uterine cancer: 30.9" "Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Thyrotropes, Prostate - Prostate glandular cells, Skin - Inner root sheath cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" CAB079003 Supported NA NA "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 1: Neuronal - Visual perception" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" "CAB079003: " "unprognostic (1.03e-1)" "unprognostic (4.35e-1)" "unprognostic (1.58e-1)" CPLX4 CPX-IV ENSG00000166569 "Complexin 4" Q7Z7G2 18 59275156-59318649 "Predicted intracellular proteins" "Exocytosis, Neurotransmitter transport, Sensory transduction, Transport, Vision" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 90 "retina: 291.7" "Group enriched" "Detected in some" 14 "Cone photoreceptor cells: 248.4;Retinal bipolar cells: 92.4;Rod photoreceptor cells: 283.2" "Cell type enriched" "Detected in single" 13 "cerebellar inhibitory: 10.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA047627 Enhanced NA NA "Cluster 42: Retina - Visual perception" "Cluster 35: Non-specific - DNA binding" "Cluster 1: Neuronal - Visual perception" "Cluster 79: Photoreceptor cells - Phototransduction" 85 "HPA047627: " CPM ENSG00000135678 "Carboxypeptidase M" P14384 12 68842197-68971570 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 146.3" "Cell type enhanced" "Detected in many" "Adipocytes: 701.7;Alveolar cells type 2: 685.6;Endometrial glandular cells: 613.0;Kupffer cells: 829.2;Macrophages: 612.0;Mast cells: 1287.1;Ocular epithelial cells: 454.4;Pericytes: 509.1;Prostatic glandular cells: 456.9;Proximal tubule cells: 716.8;Syncytiotrophoblasts: 511.1;Transitional alveolar cells: 509.0" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 193.5;oligodendrocyte: 317.8;pericyte: 469.3" "Cancer enhanced" "Detected in all" "Lung Adenocarcinoma (TCGA): 64.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 21.1;intermediate monocyte: 14.5;myeloid DC: 16.7;non-classical monocyte: 7.5" "Group enriched" "Detected in many" 5 "dendritic cells: 16.7;monocytes: 21.1" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Macrophages, Pancreas - Macrophages, Skin - Keratinocyte (granular), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002657, HPA077243" Enhanced Uncertain Vesicles NA NA 3200000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 11: White matter - Signal transduction" "Cluster 15: Kidney cancer - Membrane components" "Cluster 58: Mast cells - Allergic inflammatory responses" 9 Vesicles "HPA002657: , HPA077243: " "unprognostic (1.71e-1)" "unprognostic (8.52e-2)" "unprognostic (1.51e-1)" "unprognostic (6.89e-2)" "unprognostic (9.00e-3)" "unprognostic (1.37e-1)" "unprognostic (1.17e-1)" "unprognostic (7.86e-2)" "unprognostic (1.69e-1)" "unprognostic (2.35e-1)" "validated prognostic favorable (1.70e-10)" "validated prognostic favorable (7.71e-4)" "unprognostic (2.69e-1)" "unprognostic (4.71e-3)" "unprognostic (5.73e-2)" "unprognostic (1.40e-1)" "unprognostic (9.20e-3)" "unprognostic (3.79e-2)" "unprognostic (5.11e-2)" "unprognostic (8.67e-2)" "unprognostic (2.97e-2)" "unprognostic (9.27e-2)" "unprognostic (1.53e-1)" "unprognostic (2.14e-1)" "unprognostic (3.08e-2)" "unprognostic (1.42e-1)" "unprognostic (2.01e-2)" "unprognostic (8.16e-3)" "unprognostic (1.07e-1)" "unprognostic (5.83e-2)" "unprognostic (2.06e-1)" CPN1 ENSG00000120054 "Carboxypeptidase N subunit 1" P15169 10 100042193-100081869 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 50 "liver: 73.2" "Group enriched" "Detected in some" 5 "Early primary spermatocytes: 15.6;Hepatocytes: 49.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "Liver Hepatocellular Carcinoma (TCGA): 37.9;Skin Cutaneous Melanoma (TCGA): 23.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "skin cancer: 35.3" "Liver - Hepatocytes" "Low region specificity" "Detected in some" "Not detected" "Not detected" "Secreted to blood" Enzyme NA NA 5600000000 "Cluster 53: Liver - Plasma proteins" "Cluster 69: Skin cancer - ECM organization" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 4 "unprognostic (4.39e-2)" "unprognostic (9.41e-2)" "unprognostic (2.47e-1)" "unprognostic (2.15e-1)" CPN2 ACBP ENSG00000178772 "Carboxypeptidase N subunit 2" P22792 3 194339768-194351328 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "liver: 204.5" "Cell type enriched" "Detected in some" 15 "Hepatocytes: 203.5" "Cell type enhanced" "Detected in single" "fibroblast: 1.1" "Cancer enriched" "Detected in some" 23 "Liver Hepatocellular Carcinoma (TCGA): 89.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 11 "liver cancer: 7.5" "Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA004732 Uncertain "Secreted to blood" "No annotated function" NA NA 299000000 9300000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 9: Non-specific - Receptor signaling" "Cluster 18: Liver cancer - Metabolism" "Cluster 93: Hepatocytes - Bile production & excretion" "HPA004732: " "unprognostic (1.39e-3)" "unprognostic (1.55e-3)" "unprognostic (2.35e-1)" "unprognostic (9.31e-3)" "potential prognostic favorable (7.69e-4)" "unprognostic (7.81e-2)" "unprognostic (6.45e-2)" CPNE1 CPN1 ENSG00000214078 "Copine 1" Q99829 20 35626031-35664956 "Plasma proteins, Predicted intracellular proteins, Transporters" "Differentiation, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065876, HPA072634" Approved Supported "Nucleoplasm,Nuclear membrane" NA NA 520000 "Cluster 7: Non-specific - Innate immune response" "Cluster 49: Non-specific - Transcription" "Cluster 30: White matter - Myelination" "Cluster 62: Non-specific - Plasma proteins" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 6 "Nucleoplasm, Nuclear membrane" "HPA065876: , HPA072634: " "unprognostic (3.72e-2)" "unprognostic (2.06e-2)" "unprognostic (1.26e-1)" "unprognostic (5.00e-2)" "unprognostic (5.63e-2)" "unprognostic (2.11e-1)" "unprognostic (1.34e-1)" "unprognostic (2.13e-1)" "unprognostic (1.37e-2)" "unprognostic (2.24e-2)" "unprognostic (1.43e-1)" "unprognostic (1.11e-1)" "unprognostic (7.26e-3)" "unprognostic (1.36e-3)" "unprognostic (4.49e-3)" "unprognostic (1.14e-1)" "unprognostic (2.53e-2)" "unprognostic (5.26e-2)" "unprognostic (1.35e-1)" "unprognostic (1.04e-1)" "unprognostic (1.58e-1)" "validated prognostic unfavorable (7.84e-4)" "validated prognostic unfavorable (3.48e-5)" "unprognostic (8.60e-3)" "unprognostic (2.88e-2)" "unprognostic (2.30e-2)" "unprognostic (7.19e-2)" "unprognostic (9.66e-2)" "unprognostic (5.68e-2)" "unprognostic (2.19e-1)" "unprognostic (7.69e-2)" CPNE2 CPN2 ENSG00000140848 "Copine 2" Q96FN4 16 57092583-57148369 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bergmann glia: 95.1;Endometrial luminal cells: 61.6;Ependymal cells: 87.1;Megakaryocytes: 105.1;Neutrophil progenitors: 99.5;Oligodendrocytes: 114.7" "Cell type enhanced" "Detected in many" "oligodendrocyte: 131.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast), Prostate - Endothelial cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041132 Approved Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 6: Leukemia - Signal transduction" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 26 "Nucleoplasm, Mitochondria, Cytosol" "HPA041132: " "unprognostic (2.59e-1)" "unprognostic (1.30e-2)" "unprognostic (2.15e-1)" "unprognostic (1.35e-2)" "unprognostic (1.25e-1)" "unprognostic (1.78e-1)" "unprognostic (2.26e-2)" "unprognostic (2.35e-3)" "unprognostic (1.00e-1)" "unprognostic (2.85e-1)" "potential prognostic favorable (6.23e-6)" "unprognostic (2.09e-3)" "unprognostic (3.37e-2)" "unprognostic (6.21e-2)" "unprognostic (1.29e-1)" "unprognostic (2.17e-2)" "unprognostic (1.59e-2)" "unprognostic (1.72e-1)" "unprognostic (9.82e-3)" "unprognostic (1.34e-1)" "unprognostic (1.97e-1)" "unprognostic (1.16e-1)" "unprognostic (1.79e-3)" "unprognostic (2.78e-1)" "unprognostic (2.02e-2)" "potential prognostic unfavorable (9.93e-4)" "unprognostic (1.51e-2)" "unprognostic (3.64e-1)" "unprognostic (7.84e-2)" "unprognostic (9.06e-2)" "unprognostic (1.89e-1)" CPNE3 ENSG00000085719 "Copine 3" O75131 8 86514435-86561498 "Plasma proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 1101.9;Esophageal suprabasal cells: 419.9;Neutrophil progenitors: 968.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029552 Uncertain Supported Nucleoplasm,Cytosol NA NA 150000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 8 "Nucleoplasm, Cytosol" "HPA029552: " "unprognostic (2.36e-1)" "unprognostic (1.19e-2)" "unprognostic (1.57e-1)" "unprognostic (7.37e-2)" "unprognostic (1.04e-1)" "unprognostic (2.11e-1)" "unprognostic (1.07e-1)" "unprognostic (2.67e-1)" "unprognostic (3.55e-1)" "unprognostic (5.56e-3)" "potential prognostic favorable (5.02e-8)" "unprognostic (3.23e-3)" "unprognostic (2.41e-1)" "unprognostic (8.43e-2)" "unprognostic (8.99e-2)" "unprognostic (1.87e-1)" "unprognostic (4.37e-1)" "unprognostic (1.11e-1)" "unprognostic (1.76e-1)" "unprognostic (1.48e-3)" "potential prognostic unfavorable (6.26e-4)" "unprognostic (1.48e-3)" "unprognostic (8.69e-2)" "unprognostic (2.57e-1)" "unprognostic (2.46e-2)" "unprognostic (8.66e-3)" "unprognostic (2.80e-1)" "unprognostic (1.69e-1)" "unprognostic (2.20e-1)" "potential prognostic unfavorable (5.70e-4)" "unprognostic (1.97e-1)" CPNE4 "COPN4, CPN4" ENSG00000196353 "Copine 4" Q96A23 3 131533555-132285410 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 8.7;prostate: 24.6" "Cell type enriched" "Detected in many" 5 "Prostatic glandular cells: 4672.5" "Cell type enhanced" "Detected in all" "deep-layer intratelencephalic: 1337.7;hippocampal CA4: 1403.7" "Cancer enriched" "Detected in some" 6 "Prostate Adenocarcinoma (TCGA): 37.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Bone cancer: 8.9" "Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Pancreas - Alpha cells, Pancreas - Beta cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA032036, HPA078300" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" "Nucleoplasm, Cytosol" "HPA032036: , HPA078300: " "unprognostic (1.47e-1)" "unprognostic (6.03e-3)" "unprognostic (8.77e-2)" "unprognostic (1.53e-1)" "unprognostic (3.41e-2)" "unprognostic (2.26e-1)" "unprognostic (1.86e-1)" "unprognostic (3.84e-2)" "unprognostic (2.05e-2)" "unprognostic (6.44e-2)" CPNE5 "COPN5, CPN5, KIAA1599" ENSG00000124772 "Copine 5" Q9HCH3 6 36740775-36839444 "Plasma proteins, Predicted intracellular proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 131.7;heart muscle: 90.0" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 92.0;Cardiomyocytes: 144.4;Epicardial cells: 63.7;Oligodendrocyte progenitor cells: 63.4;Plasma cells: 159.0;Platelets: 114.0;Retinal amacrine cells: 139.6;Sertoli cells: 215.3" "Cell type enhanced" "Detected in all" "medium spiny neuron: 206.2" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 28.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 71 "memory B-cell: 51.7;naive B-cell: 26.9" "Lineage enriched" "Detected in single" 93 "B-cells: 51.7" "Group enriched" "Detected in some" 5 "lymphoma: 23.0;Myeloma: 27.6" "Adipose visceral - Mesothelial cells, Minor Salivary Gland - Plasma cells, Prostate - Fibroblasts, Stomach - Plasma cells, Testis - Sertoli cells" "Region enhanced" "Detected in many" "basal ganglia: 103.4" "Region enhanced" "Detected in many" "basal ganglia: 178.3" HPA031369 Enhanced Approved Cytosol NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 35: Neurons - Synaptic function & neurogenesis" 2 Cytosol "HPA031369: " "unprognostic (1.35e-2)" "unprognostic (4.07e-2)" "unprognostic (1.50e-1)" "unprognostic (9.47e-3)" "unprognostic (1.69e-1)" "unprognostic (3.33e-1)" "unprognostic (8.66e-2)" "unprognostic (2.84e-1)" "potential prognostic favorable (4.60e-4)" "unprognostic (2.66e-2)" "unprognostic (6.32e-2)" "unprognostic (2.05e-3)" "potential prognostic unfavorable (1.79e-4)" "unprognostic (3.23e-2)" "unprognostic (5.55e-2)" "unprognostic (1.02e-2)" "unprognostic (8.08e-2)" "unprognostic (3.60e-2)" "unprognostic (7.54e-2)" "unprognostic (1.45e-2)" "unprognostic (5.94e-2)" "unprognostic (1.09e-1)" "unprognostic (3.11e-1)" "unprognostic (3.88e-2)" "unprognostic (2.35e-2)" "unprognostic (4.95e-2)" "unprognostic (1.61e-1)" "unprognostic (3.22e-2)" "unprognostic (1.55e-1)" "unprognostic (1.31e-1)" "unprognostic (1.01e-2)" CPNE6 ENSG00000100884 "Copine 6" O95741 14 24070837-24078100 "Plasma proteins, Predicted intracellular proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 45.5;retina: 22.1;seminal vesicle: 21.4" "Cell type enhanced" "Detected in some" "Astrocytes: 29.2;Brain excitatory neurons: 19.3;Brain inhibitory neurons: 18.8;Epididymal efferent duct absorptive cells: 37.5;Late spermatids: 26.3;Other brain neurons: 14.0;Proximal tubule cells: 25.6;Retinal amacrine cells: 9.4;Smooth muscle cells: 8.6" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in single" "Glioblastoma Multiforme (TCGA): 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 11 "Uterine cancer: 5.7" "Adipose subcutaneous - Smooth muscle cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031636, HPA076665" Enhanced Approved "Golgi apparatus,Vesicles" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 35: Neurons - Synaptic function & neurogenesis" 1 "Golgi apparatus" Vesicles "HPA031636: , HPA076665: " "unprognostic (1.07e-2)" "unprognostic (1.48e-1)" "unprognostic (1.50e-1)" CPNE7 ENSG00000178773 "Copine 7" Q9UBL6 16 89575758-89597246 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.9;epididymis: 18.2;pituitary gland: 13.3" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 16.5;Corticotrophs: 38.9;Differentiating spermatogonia: 34.7;Epididymal principal cells: 75.0;Innate lymphoid cells: 48.2;Other brain neurons: 23.5;Renal collecting duct principal cells: 22.4;Retinal amacrine cells: 22.8;Thymocytes: 16.9" "Cell type enhanced" "Detected in many" "deep-layer near-projecting: 121.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 4.9" "Lineage enriched" "Detected in single" 5 "T-cells: 4.9" "Low cancer specificity" "Detected in many" "Pituitary gland - Corticotropes, Thyroid gland - T-cells" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA043359 Uncertain NA NA "Cluster 1: T-cells - Unknown function" "Cluster 22: Epididymis - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" "HPA043359: " "unprognostic (1.58e-3)" "unprognostic (1.11e-1)" "unprognostic (3.31e-1)" "unprognostic (3.37e-1)" "unprognostic (1.58e-2)" "unprognostic (3.52e-1)" "unprognostic (1.00e-2)" "unprognostic (1.82e-2)" "unprognostic (2.11e-1)" "potential prognostic unfavorable (4.02e-9)" "unprognostic (6.58e-3)" "unprognostic (7.32e-2)" "unprognostic (3.30e-1)" "unprognostic (9.73e-3)" "unprognostic (8.33e-2)" "unprognostic (2.00e-1)" "unprognostic (8.11e-2)" "unprognostic (1.01e-1)" "unprognostic (4.95e-2)" "unprognostic (3.73e-2)" "unprognostic (1.59e-1)" "unprognostic (3.27e-3)" "unprognostic (5.03e-2)" "unprognostic (1.13e-1)" "unprognostic (1.17e-2)" "unprognostic (1.88e-2)" "unprognostic (4.56e-2)" "unprognostic (3.86e-1)" "unprognostic (1.13e-1)" CPNE8 ENSG00000139117 "Copine 8" Q86YQ8 12 38646822-38907430 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Lymphatic endothelial cells: 304.3;Podocytes: 864.4;Vascular endothelial cells: 401.4" "Cell type enhanced" "Detected in many" "endothelial cell: 566.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Spleen - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038600 Approved NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 12 "HPA038600: " "unprognostic (4.77e-2)" "unprognostic (4.33e-1)" "unprognostic (1.55e-1)" "unprognostic (2.49e-2)" "unprognostic (4.25e-1)" "unprognostic (7.75e-2)" "unprognostic (4.87e-3)" "potential prognostic unfavorable (3.99e-5)" "unprognostic (1.88e-2)" "unprognostic (3.01e-2)" "potential prognostic favorable (1.14e-4)" "unprognostic (4.47e-3)" "unprognostic (1.18e-1)" "unprognostic (7.32e-2)" "unprognostic (1.26e-1)" "unprognostic (1.36e-2)" "potential prognostic unfavorable (2.14e-4)" "unprognostic (1.65e-1)" "unprognostic (1.29e-2)" "unprognostic (9.51e-2)" "unprognostic (4.27e-2)" "unprognostic (9.11e-3)" "potential prognostic unfavorable (9.60e-5)" "unprognostic (4.61e-1)" "unprognostic (3.45e-1)" "unprognostic (3.17e-2)" "unprognostic (9.71e-3)" "potential prognostic unfavorable (4.00e-5)" "unprognostic (1.88e-1)" "unprognostic (6.01e-2)" "potential prognostic unfavorable (4.62e-4)" CPNE9 KIAA4217 ENSG00000144550 "Copine family member 9" Q8IYJ1 3 9703826-9729908 "Predicted intracellular proteins" Differentiation "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 36.8" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 30.7;Early spermatids: 17.5;Late spermatids: 99.9;Other brain neurons: 16.3;Retinal ganglion cells: 11.6" "Group enriched" "Detected in all" 4 "lower rhombic lip: 203.7;mammillary body: 178.2;thalamic excitatory: 107.7" "Cancer enriched" "Detected in single" 4 "Testicular Germ Cell Tumor (TCGA): 3.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "intermediate monocyte: 1.0" "Lineage enhanced" "Detected in single" "monocytes: 1.0" "Not detected" "Not detected" "Colon - Colon enteroendocrine cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060813 Approved "Plasma membrane,Cytosol" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 27: Cerebellum - Synaptic function" "Cluster 49: Hindbrain - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" 3 Cytosol "Plasma membrane" "HPA060813: " "unprognostic (1.26e-1)" "unprognostic (1.06e-1)" CPO ENSG00000144410 "Carboxypeptidase O" Q8IVL8 2 206939518-206969474 "Enzymes, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "intestine: 105.3" "Cell type enriched" "Detected in many" 20 "Enterocytes: 393.3" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 29 "basophil: 11.9" "Lineage enriched" "Detected in single" 83 "granulocytes: 11.9" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells, Testis - Late spermatids" "Not detected" "Not detected" "Intracellular and membrane" Enzyme NA NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 1: Enterocytes - Absorption and Digestion" "unprognostic (1.82e-1)" "unprognostic (1.02e-2)" CPOX "CPO, CPX, HCP" ENSG00000080819 "Coproporphyrinogen oxidase" P36551 3 98579446-98593648 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Heme biosynthesis, Porphyrin biosynthesis" Oxidoreductase "Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Erythrocyte progenitors: 52.8;Oligodendrocytes: 27.9" "Cell type enriched" "Detected in all" 4 "oligodendrocyte: 42.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015736, HPA054448" Supported Mitochondria No No 160000 "Cluster 14: Non-specific - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 4 Mitochondria "HPA015736: , HPA054448: " "unprognostic (3.37e-1)" "unprognostic (5.62e-2)" "unprognostic (1.24e-2)" "unprognostic (4.53e-3)" "unprognostic (1.42e-1)" "unprognostic (1.54e-1)" "unprognostic (1.67e-1)" "unprognostic (1.53e-1)" "unprognostic (1.25e-1)" "unprognostic (1.02e-2)" "validated prognostic unfavorable (5.00e-4)" "validated prognostic unfavorable (6.77e-5)" "unprognostic (1.79e-1)" "unprognostic (2.25e-3)" "unprognostic (3.68e-2)" "unprognostic (8.86e-2)" "potential prognostic unfavorable (6.52e-4)" "unprognostic (9.09e-3)" "unprognostic (2.37e-1)" "unprognostic (2.99e-1)" "unprognostic (5.01e-2)" "unprognostic (8.94e-3)" "potential prognostic unfavorable (8.34e-4)" "unprognostic (2.03e-3)" "unprognostic (8.28e-3)" "unprognostic (3.15e-1)" "unprognostic (6.26e-2)" "unprognostic (1.56e-1)" "unprognostic (1.36e-2)" "unprognostic (5.10e-3)" "unprognostic (1.59e-1)" CPPED1 "CSTP1, FLJ11151" ENSG00000103381 "Calcineurin like phosphoesterase domain containing 1" Q9BRF8 16 12659799-12803887 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Neutrophils: 1636.4" "Cell type enhanced" "Detected in all" "pericyte: 169.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 676.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040938, HPA041970" Uncertain Supported "Plasma membrane,Cytosol" No No 580000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 76: Non-specific - Metabolism" "Cluster 30: White matter - Myelination" "Cluster 49: HMC-1 - Innate immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 2 Cytosol "Plasma membrane" "HPA040938: , HPA041970: " "unprognostic (1.50e-1)" "potential prognostic unfavorable (1.14e-4)" "unprognostic (2.29e-1)" "unprognostic (1.03e-1)" "unprognostic (1.40e-2)" "unprognostic (5.59e-2)" "potential prognostic unfavorable (1.87e-4)" "unprognostic (3.11e-3)" "unprognostic (1.03e-1)" "unprognostic (2.59e-1)" "potential prognostic favorable (3.84e-9)" "unprognostic (7.26e-2)" "unprognostic (3.16e-1)" "unprognostic (3.29e-1)" "unprognostic (1.94e-1)" "unprognostic (6.75e-2)" "unprognostic (1.21e-1)" "unprognostic (8.34e-2)" "unprognostic (1.41e-1)" "unprognostic (1.41e-1)" "unprognostic (7.43e-3)" "unprognostic (3.06e-2)" "unprognostic (1.65e-1)" "unprognostic (4.10e-1)" "unprognostic (2.13e-1)" "unprognostic (2.83e-1)" "unprognostic (2.80e-1)" "unprognostic (9.30e-2)" "unprognostic (1.83e-1)" "potential prognostic unfavorable (2.64e-4)" "unprognostic (4.54e-1)" CPQ "LDP, PGCP" ENSG00000104324 "Carboxypeptidase Q" Q9Y646 8 96645242-97149654 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 212.0" "Cell type enriched" "Detected in many" 4 "Neutrophils: 2620.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 251.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Kidney - Fibroblasts, Pituitary gland - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023235, HPA024490" Enhanced Supported "Golgi apparatus,Vesicles" "Secreted to blood" Enzyme NA NA 17000000 "Cluster 7: Non-specific - Innate immune response" "Cluster 72: Kidney - Transmembrane transport" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 24: Neutrophils - Innate immunity signal integration" "Golgi apparatus, Vesicles" "HPA023235: , HPA024490: " "potential prognostic favorable (5.29e-5)" "unprognostic (7.22e-2)" "unprognostic (2.95e-2)" "unprognostic (6.07e-2)" "unprognostic (8.08e-2)" "validated prognostic unfavorable (4.64e-7)" "validated prognostic unfavorable (3.09e-5)" "unprognostic (2.37e-3)" "unprognostic (9.63e-2)" "potential prognostic favorable (1.75e-9)" "unprognostic (1.92e-2)" "unprognostic (2.79e-2)" "unprognostic (1.13e-1)" "unprognostic (8.95e-2)" "unprognostic (1.34e-1)" "unprognostic (2.40e-3)" "unprognostic (4.10e-1)" "unprognostic (5.01e-2)" "unprognostic (1.12e-3)" "unprognostic (2.56e-3)" "unprognostic (2.81e-3)" "unprognostic (4.45e-2)" "unprognostic (7.68e-2)" "unprognostic (9.23e-2)" "unprognostic (2.45e-2)" "unprognostic (7.56e-3)" "unprognostic (7.35e-2)" "unprognostic (2.36e-2)" "unprognostic (5.23e-2)" CPS1 GATD6 ENSG00000021826 "Carbamoyl-phosphate synthase 1" P31327 2 210477682-210679107 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Urea cycle" "Allosteric enzyme, Ligase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 994.6" "Cell type enriched" "Detected in many" 20 "Hepatocytes: 2626.5" "Cell type enhanced" "Detected in many" "oligodendrocyte: 45.8" "Group enriched" "Detected in many" 16 "Liver Hepatocellular Carcinoma (TCGA): 133.0;Lung Adenocarcinoma (TCGA): 39.0;Stomach Adenocarcinoma (TCGA): 34.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 121.4" "Adrenal gland - Fibroblasts, Kidney - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "CAB003781, HPA021400" Enhanced Supported "Nucleoli,Nucleoli rim,Mid piece,Principal piece" NA NA 12000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 30: White matter - Myelination" "Cluster 7: Liver cancer - Metabolism" "Cluster 93: Hepatocytes - Bile production & excretion" 4 "Nucleoli, Nucleoli rim" "Mid piece, Principal piece" "CAB003781: , HPA021400: " "unprognostic (3.14e-1)" "unprognostic (9.84e-2)" "unprognostic (7.99e-2)" "unprognostic (5.27e-2)" "unprognostic (3.14e-1)" "unprognostic (3.76e-2)" "unprognostic (1.14e-1)" "unprognostic (1.81e-1)" "unprognostic (6.22e-2)" "unprognostic (8.44e-3)" "potential prognostic unfavorable (6.37e-5)" "validated prognostic favorable (1.61e-4)" "validated prognostic favorable (5.38e-5)" "unprognostic (4.62e-3)" "unprognostic (2.92e-1)" "unprognostic (1.29e-2)" "unprognostic (2.00e-1)" "unprognostic (6.87e-3)" "unprognostic (3.20e-2)" "unprognostic (9.55e-2)" "unprognostic (1.70e-3)" "unprognostic (1.44e-1)" "unprognostic (4.34e-2)" "unprognostic (1.39e-1)" "unprognostic (5.88e-2)" "unprognostic (2.16e-1)" "unprognostic (1.28e-2)" CPSF1 CPSF160 ENSG00000071894 "Cleavage and polyadenylation specific factor 1" Q10570 8 144393229-144409335 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing" RNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 53.9;Sertoli cells: 65.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065167, HPA068906" Supported Nucleoplasm No No "Cluster 33: Non-specific - ATP binding" "Cluster 24: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 65: Non-specific - Cell growth & division" 42 Nucleoplasm "HPA065167: , HPA068906: " "unprognostic (8.90e-2)" "unprognostic (1.51e-1)" "unprognostic (2.60e-1)" "unprognostic (6.50e-2)" "unprognostic (4.87e-2)" "unprognostic (6.44e-2)" "unprognostic (1.32e-1)" "unprognostic (1.05e-3)" "unprognostic (5.43e-2)" "unprognostic (6.56e-2)" "potential prognostic unfavorable (2.29e-5)" "unprognostic (2.07e-1)" "unprognostic (7.12e-2)" "unprognostic (4.24e-3)" "unprognostic (5.47e-2)" "unprognostic (7.62e-2)" "unprognostic (2.37e-1)" "unprognostic (3.57e-2)" "unprognostic (6.79e-2)" "unprognostic (1.33e-1)" "unprognostic (2.93e-3)" "unprognostic (3.73e-2)" "unprognostic (3.52e-3)" "unprognostic (1.69e-1)" "unprognostic (6.95e-2)" "unprognostic (9.50e-2)" "unprognostic (1.09e-3)" "unprognostic (3.12e-1)" "unprognostic (4.73e-2)" "unprognostic (5.48e-2)" "unprognostic (3.25e-1)" CPSF2 "CPSF100, KIAA1367" ENSG00000165934 "Cleavage and polyadenylation specific factor 2" Q9P2I0 14 92121969-92172145 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024238 Supported Approved Nucleoplasm,Vesicles NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 39: Testis - Nuclear processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 17: Non-specific - RNA processing" 31 Nucleoplasm Vesicles "HPA024238: " "unprognostic (1.18e-1)" "unprognostic (1.80e-1)" "unprognostic (3.73e-1)" "unprognostic (2.05e-2)" "unprognostic (2.11e-1)" "unprognostic (2.36e-2)" "unprognostic (1.73e-2)" "unprognostic (1.27e-1)" "unprognostic (3.19e-2)" "potential prognostic unfavorable (9.23e-4)" "potential prognostic favorable (1.23e-4)" "unprognostic (8.71e-2)" "unprognostic (2.10e-1)" "potential prognostic unfavorable (2.03e-4)" "unprognostic (6.78e-2)" "potential prognostic unfavorable (9.78e-4)" "unprognostic (2.14e-3)" "unprognostic (1.70e-1)" "unprognostic (1.15e-1)" "unprognostic (2.31e-1)" "unprognostic (3.34e-3)" "unprognostic (3.52e-3)" "unprognostic (9.47e-2)" "unprognostic (2.45e-1)" "unprognostic (1.26e-1)" "unprognostic (1.28e-1)" "unprognostic (1.05e-2)" "unprognostic (8.13e-2)" "unprognostic (3.49e-1)" "unprognostic (2.83e-2)" "unprognostic (7.39e-2)" CPSF3 "CPSF-73, CPSF73, YSH1" ENSG00000119203 "Cleavage and polyadenylation specific factor 3" Q9UKF6 2 9423651-9473101 "Disease related genes, Essential proteins, Predicted intracellular proteins" "mRNA processing" "Endonuclease, Hydrolase, Nuclease, Ribonucleoprotein, RNA-binding" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 114.7;Early spermatids: 156.7;Late primary spermatocytes: 366.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Macrophages, Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034657 Uncertain NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 39: Testis - Nuclear processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 24 "HPA034657: " "unprognostic (2.48e-3)" "unprognostic (5.95e-2)" "unprognostic (2.01e-1)" "unprognostic (2.12e-1)" "unprognostic (3.02e-1)" "unprognostic (1.12e-2)" "unprognostic (1.71e-1)" "unprognostic (2.44e-3)" "unprognostic (4.38e-2)" "unprognostic (1.01e-1)" "unprognostic (1.82e-3)" "unprognostic (5.06e-2)" "unprognostic (5.56e-3)" "validated prognostic unfavorable (8.98e-7)" "validated prognostic unfavorable (2.33e-5)" "unprognostic (3.04e-3)" "unprognostic (1.48e-2)" "potential prognostic favorable (8.12e-4)" "unprognostic (2.92e-1)" "unprognostic (1.44e-1)" "unprognostic (7.52e-2)" "unprognostic (4.34e-2)" "unprognostic (8.79e-3)" "unprognostic (1.75e-1)" "unprognostic (3.33e-2)" "unprognostic (6.60e-2)" "unprognostic (2.34e-1)" "unprognostic (3.63e-1)" "unprognostic (1.54e-1)" "unprognostic (6.37e-2)" "unprognostic (1.57e-1)" CPSF4 "CPSF30, NAR" ENSG00000160917 "Cleavage and polyadenylation specific factor 4" O95639 7 99438922-99457373 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, mRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 73.9;Migrating cytotrophoblasts: 61.1;Sertoli cells: 64.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049094, HPA066470" Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 24: Non-specific - Transcription" "Cluster 44: Non-specific - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 18 Nucleoplasm Vesicles "HPA049094: , HPA066470: " "unprognostic (1.38e-1)" "unprognostic (6.62e-2)" "unprognostic (4.21e-2)" "unprognostic (1.22e-2)" "unprognostic (3.64e-1)" "unprognostic (1.41e-1)" "unprognostic (7.30e-3)" "unprognostic (8.52e-2)" "unprognostic (1.06e-1)" "unprognostic (1.02e-3)" "unprognostic (8.36e-3)" "unprognostic (3.30e-2)" "unprognostic (1.73e-2)" "validated prognostic unfavorable (4.52e-5)" "validated prognostic unfavorable (2.69e-6)" "unprognostic (1.54e-1)" "unprognostic (1.27e-1)" "unprognostic (3.96e-3)" "unprognostic (5.72e-2)" "unprognostic (2.82e-1)" "unprognostic (6.25e-2)" "unprognostic (8.13e-3)" "potential prognostic unfavorable (1.71e-5)" "unprognostic (1.50e-3)" "unprognostic (1.06e-1)" "unprognostic (2.95e-1)" "unprognostic (1.52e-2)" "unprognostic (4.72e-2)" "unprognostic (2.69e-1)" "unprognostic (1.86e-1)" "unprognostic (1.05e-1)" CPSF4L ENSG00000187959 "Cleavage and polyadenylation specific factor 4 like" A6NMK7 17 73248449-73262352 "Predicted intracellular proteins" RNA-binding "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 5.5;Hepatic stellate cells: 6.5;Müller glia: 6.3;Oocytes: 32.2;Paneth cells: 7.7;Pituicytes/FSCs: 6.6;Salivary basal cells: 16.9" "Cell type enhanced" "Detected in some" "astrocyte: 1.1;Bergmann glia: 1.4" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Rhabdoid: 5.1" "Region enriched" "Detected in single" 36 "cerebellum: 10.2" "Low region specificity" "Detected in many" HPA044047 Uncertain NA NA "Cluster 2: Neurons - Nucleosome" "Cluster 5: Rhabdoid - Unknown function" "Cluster 103: Non-specific - Basic cellular processes" "HPA044047: " "unprognostic (1.16e-1)" "unprognostic (1.34e-2)" "unprognostic (7.29e-3)" CPSF6 "CFIM, CFIM68, CFIM72, HPBRII-4, HPBRII-7" ENSG00000111605 "Cleavage and polyadenylation specific factor 6" Q16630 12 69239569-69274358 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039973 Supported Enhanced "Nucleoplasm,Nuclear speckles" No No 230000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 61: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 17: Non-specific - RNA processing" 318 "Nucleoplasm, Nuclear speckles" "HPA039973: " "unprognostic (3.54e-1)" "unprognostic (2.34e-1)" "unprognostic (2.71e-1)" "unprognostic (1.62e-2)" "unprognostic (2.58e-2)" "unprognostic (5.89e-2)" "unprognostic (8.11e-2)" "unprognostic (1.79e-2)" "unprognostic (1.02e-1)" "potential prognostic unfavorable (2.72e-6)" "potential prognostic favorable (1.05e-4)" "unprognostic (1.18e-2)" "unprognostic (1.13e-1)" "potential prognostic unfavorable (1.19e-8)" "unprognostic (6.17e-3)" "potential prognostic unfavorable (3.75e-4)" "unprognostic (4.51e-2)" "unprognostic (6.40e-2)" "unprognostic (4.95e-2)" "unprognostic (3.89e-1)" "unprognostic (8.13e-2)" "unprognostic (1.54e-3)" "unprognostic (7.72e-3)" "unprognostic (9.82e-2)" "unprognostic (4.54e-2)" "unprognostic (2.11e-2)" "unprognostic (3.43e-2)" "unprognostic (1.01e-1)" "unprognostic (1.65e-1)" "unprognostic (9.52e-2)" "unprognostic (1.04e-2)" CPSF7 "CFIM59, FLJ12529" ENSG00000149532 "Cleavage and polyadenylation specific factor 7" Q8N684 11 61402641-61430031 "Predicted intracellular proteins" "mRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 182.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041094 Supported Supported Nucleoplasm,Cytosol NA NA 150000 "Cluster 7: Non-specific - Innate immune response" "Cluster 24: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 24: Non-specific - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 50 Nucleoplasm Cytosol "HPA041094: " "unprognostic (7.11e-2)" "unprognostic (7.36e-2)" "unprognostic (7.82e-2)" "unprognostic (1.44e-2)" "unprognostic (8.52e-2)" "unprognostic (3.50e-1)" "unprognostic (9.61e-2)" "unprognostic (1.04e-1)" "unprognostic (7.46e-3)" "potential prognostic unfavorable (6.10e-4)" "unprognostic (1.65e-2)" "unprognostic (2.41e-3)" "unprognostic (1.19e-1)" "unprognostic (4.17e-3)" "unprognostic (1.26e-1)" "unprognostic (2.01e-2)" "unprognostic (1.33e-3)" "unprognostic (1.76e-1)" "unprognostic (1.02e-1)" "unprognostic (1.58e-1)" "unprognostic (2.03e-1)" "unprognostic (5.09e-2)" "unprognostic (1.44e-2)" "unprognostic (9.46e-2)" "unprognostic (1.92e-2)" "unprognostic (2.03e-1)" "unprognostic (3.32e-3)" "unprognostic (1.86e-1)" "unprognostic (3.92e-1)" "unprognostic (1.46e-1)" "unprognostic (1.78e-1)" CPT1A "CPT1, CPT1-L, L-CPT1" ENSG00000110090 "Carnitine palmitoyltransferase 1A" P50416 11 68754620-68844410 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Transport" "Acyltransferase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cell type enhanced" "Detected in many" "endothelial cell: 107.2;fibroblast: 115.9;pericyte: 122.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008835 Supported Supported Mitochondria NA NA 19000 "Cluster 41: Basophils - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 7: Liver cancer - Metabolism" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 12 Mitochondria "HPA008835: " "unprognostic (2.08e-2)" "potential prognostic unfavorable (7.37e-5)" "unprognostic (2.26e-1)" "unprognostic (2.13e-1)" "unprognostic (2.76e-2)" "unprognostic (1.18e-1)" "unprognostic (3.20e-2)" "unprognostic (2.93e-1)" "unprognostic (1.07e-1)" "unprognostic (2.56e-1)" "validated prognostic favorable (6.86e-8)" "validated prognostic favorable (3.74e-4)" "unprognostic (6.29e-2)" "unprognostic (1.75e-1)" "unprognostic (9.40e-3)" "unprognostic (1.62e-1)" "unprognostic (2.11e-1)" "unprognostic (7.09e-2)" "unprognostic (3.83e-1)" "unprognostic (1.33e-3)" "unprognostic (9.86e-2)" "unprognostic (2.52e-2)" "unprognostic (2.91e-2)" "unprognostic (1.96e-1)" "unprognostic (1.74e-2)" "unprognostic (9.03e-2)" "unprognostic (4.41e-1)" "unprognostic (3.67e-1)" "unprognostic (3.02e-1)" "unprognostic (6.06e-2)" "unprognostic (2.89e-1)" CPT1B "CPT1-M, M-CPT1" ENSG00000205560 "Carnitine palmitoyltransferase 1B" Q92523 22 50568861-50578465 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism, Transport" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "heart muscle: 226.2;skeletal muscle: 136.9;testis: 75.9;tongue: 212.9" "Cell type enhanced" "Detected in some" "Astrocytes: 12.8;Bergmann glia: 6.8;Brain excitatory neurons: 7.5;Brain inhibitory neurons: 10.6;Ependymal cells: 5.5;Epididymal efferent duct ciliated cells: 5.5;Foveolar cells: 14.8;Late primary spermatocytes: 5.8;Late spermatids: 21.4;Microglia: 5.5;Oligodendrocyte progenitor cells: 7.1;Oligodendrocytes: 12.1;Other brain neurons: 5.9" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 57.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA079265 Enhanced NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 6: Non-specific - Immune response" "Cluster 56: Non-specific - Sensory perception" "Cluster 22: Non-specific - Basic cellular functions" 2 "HPA079265: " "unprognostic (2.05e-2)" "unprognostic (8.85e-2)" "unprognostic (3.58e-1)" "unprognostic (1.46e-1)" "unprognostic (8.38e-2)" "unprognostic (1.18e-1)" "unprognostic (8.28e-2)" "potential prognostic favorable (1.69e-4)" "unprognostic (3.95e-2)" "unprognostic (1.35e-1)" "potential prognostic unfavorable (7.04e-4)" "unprognostic (1.57e-1)" "unprognostic (4.89e-3)" "unprognostic (3.17e-1)" "unprognostic (4.11e-3)" "unprognostic (2.07e-2)" "unprognostic (2.90e-1)" "unprognostic (1.06e-1)" "unprognostic (1.16e-1)" "unprognostic (2.80e-1)" "potential prognostic favorable (4.21e-4)" "unprognostic (1.53e-3)" "unprognostic (5.48e-3)" "unprognostic (4.07e-2)" "unprognostic (2.59e-2)" "unprognostic (6.85e-2)" "unprognostic (2.09e-1)" "unprognostic (6.39e-2)" "unprognostic (2.58e-2)" "unprognostic (1.27e-2)" "potential prognostic favorable (4.86e-5)" CPT1C "CATL1, CPT1P, CPTIC, FLJ23809" ENSG00000169169 "Carnitine palmitoyltransferase 1C" Q8TCG5 19 49690898-49713731 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.3;choroid plexus: 27.7;pituitary gland: 26.9" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 42.5;Brain excitatory neurons: 47.3;Brain inhibitory neurons: 55.8;Choroid plexus epithelial cells: 55.8;Decidual stromal cells: 45.4;Late spermatids: 57.8;Other brain neurons: 40.6;Retinal amacrine cells: 38.5;Retinal bipolar cells: 63.6;Retinal ganglion cells: 54.1;Retinal horizontal cells: 76.1;Retinal pigment epithelial cells: 42.6" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 28.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 41.9;Rhabdoid: 50.9" "Adipose visceral - Adipose progenitor cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063621 Approved NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "HPA063621: " "unprognostic (1.25e-1)" "unprognostic (1.92e-1)" "unprognostic (2.48e-2)" "unprognostic (1.72e-1)" "unprognostic (3.47e-2)" "unprognostic (1.46e-1)" "unprognostic (1.07e-1)" "unprognostic (2.14e-3)" "unprognostic (2.97e-2)" "unprognostic (1.06e-3)" "unprognostic (7.65e-3)" "unprognostic (1.61e-1)" "unprognostic (1.36e-1)" "unprognostic (1.19e-1)" "unprognostic (1.32e-2)" "unprognostic (9.64e-2)" "unprognostic (1.85e-1)" "potential prognostic favorable (4.89e-4)" "unprognostic (2.72e-1)" "unprognostic (1.55e-1)" "unprognostic (5.55e-2)" "unprognostic (1.55e-1)" "unprognostic (1.16e-2)" "unprognostic (1.26e-1)" "unprognostic (1.47e-2)" "unprognostic (1.41e-1)" CPT2 "CPT1, CPTASE" ENSG00000157184 "Carnitine palmitoyltransferase 2" P23786 1 53196792-53214197 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Transport" "Acyltransferase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 85.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 107.9;Early primary spermatocytes: 71.2;Hepatocytes: 102.4;Retinal pigment epithelial cells: 63.9;Syncytiotrophoblasts: 68.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028201, HPA028202, HPA028214" Enhanced Approved Nucleoplasm,Nucleoli,Mitochondria Yes No "Cluster 25: Non-specific - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 8: Immune cells - Immune response" "Cluster 37: Non-specific - mRNA processing" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 10 "Nucleoplasm, Mitochondria" Nucleoli "HPA028201: , HPA028202: , HPA028214: " "unprognostic (2.00e-1)" "unprognostic (1.53e-1)" "unprognostic (3.45e-2)" "unprognostic (1.34e-1)" "potential prognostic favorable (9.04e-6)" "unprognostic (1.58e-1)" "unprognostic (4.97e-1)" "unprognostic (7.57e-2)" "unprognostic (2.20e-1)" "potential prognostic unfavorable (1.28e-4)" "potential prognostic favorable (8.96e-12)" "unprognostic (2.09e-3)" "unprognostic (1.66e-3)" "unprognostic (1.99e-1)" "unprognostic (1.85e-2)" "unprognostic (1.36e-1)" "unprognostic (9.19e-2)" "unprognostic (1.11e-2)" "unprognostic (1.33e-2)" "unprognostic (2.23e-1)" "unprognostic (9.06e-2)" "unprognostic (7.54e-2)" "unprognostic (1.71e-3)" "unprognostic (3.32e-1)" "unprognostic (8.32e-2)" "unprognostic (4.42e-2)" "unprognostic (8.84e-2)" "unprognostic (5.01e-3)" "unprognostic (2.24e-1)" "unprognostic (1.41e-1)" "unprognostic (6.41e-2)" CPTP "GLTPD1, MGC10334" ENSG00000224051 "Ceramide-1-phosphate transfer protein" Q5TA50 1 1324756-1328896 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 82.0;Early spermatids: 66.3;Enterocytes: 65.5;Esophageal apical cells: 272.7;Esophageal suprabasal cells: 67.2;Late primary spermatocytes: 137.3;Late spermatids: 286.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" HPA056832 Approved Supported "Cytosol,Perinuclear theca,Flagellar centriole,Mid piece" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" "Cytosol, Flagellar centriole, Mid piece" "Perinuclear theca" "HPA056832: " "unprognostic (2.40e-1)" "unprognostic (2.75e-1)" "unprognostic (9.82e-2)" "unprognostic (3.67e-2)" "unprognostic (6.54e-2)" "unprognostic (6.87e-2)" "unprognostic (1.45e-1)" "unprognostic (3.46e-3)" "unprognostic (7.69e-2)" "unprognostic (1.10e-2)" "unprognostic (1.17e-1)" "potential prognostic favorable (2.56e-5)" "unprognostic (1.01e-1)" "unprognostic (1.77e-1)" "unprognostic (2.32e-1)" "unprognostic (5.30e-2)" "unprognostic (9.54e-2)" "unprognostic (2.27e-2)" "unprognostic (2.06e-1)" "unprognostic (3.01e-2)" "unprognostic (1.33e-1)" "unprognostic (1.88e-1)" "potential prognostic unfavorable (2.36e-4)" "unprognostic (2.12e-1)" "unprognostic (1.42e-1)" "unprognostic (2.67e-2)" "unprognostic (5.18e-2)" "unprognostic (1.43e-1)" "unprognostic (1.38e-2)" CPVL ENSG00000106066 "Carboxypeptidase vitellogenic like" Q9H3G5 7 28995235-29195451 "Enzymes, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 192.1;lymphoid tissue: 206.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 1565.1;cDC: 1103.0;Hofbauer cells: 520.5;Kupffer cells: 547.3;Macrophages: 423.0;Microglia: 249.9;Migrating cytotrophoblasts: 337.2;monocytes: 390.6" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 267.7;choroid plexus epithelial cell: 126.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 1139.6;intermediate monocyte: 955.1;myeloid DC: 1321.5" "Group enriched" "Detected in all" 52 "dendritic cells: 1321.5;monocytes: 1139.6" "Cancer enhanced" "Detected in many" "testis cancer: 89.4" "Adipose subcutaneous - Macrophages, Adrenal gland - Macrophages, Colon - Fibroblasts, Heart muscle - Cardiomyocytes, Liver - Kupffer cells, Lung - Macrophages, Minor Salivary Gland - Macrophages, Prostate - Fibroblasts, Spleen - Macrophages, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB003697, HPA045715, HPA056466" Enhanced Approved "Endoplasmic reticulum" "Intracellular and membrane" Enzyme NA NA 840000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 25: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 82: Dendritic cells - Antigen presentation" 39 "Endoplasmic reticulum" "CAB003697: , HPA045715: , HPA056466: " "unprognostic (2.14e-1)" "unprognostic (5.92e-2)" "unprognostic (1.26e-1)" "unprognostic (2.31e-1)" "unprognostic (2.08e-2)" "unprognostic (1.58e-1)" "unprognostic (1.15e-1)" "unprognostic (1.44e-2)" "unprognostic (2.58e-3)" "unprognostic (2.49e-1)" "unprognostic (9.72e-3)" "unprognostic (2.05e-1)" "unprognostic (3.41e-3)" "unprognostic (7.51e-3)" "unprognostic (7.99e-2)" "unprognostic (3.50e-2)" "unprognostic (4.66e-2)" "unprognostic (1.35e-1)" "unprognostic (4.06e-3)" "unprognostic (4.05e-2)" "unprognostic (3.24e-2)" "unprognostic (2.90e-1)" "unprognostic (1.65e-2)" "unprognostic (5.16e-2)" "unprognostic (2.14e-1)" "unprognostic (6.03e-2)" "unprognostic (1.93e-1)" "unprognostic (2.07e-3)" "unprognostic (2.30e-1)" "unprognostic (5.03e-2)" "unprognostic (7.69e-2)" CPXCR1 CT77 ENSG00000147183 "CPX chromosome region candidate 1" Q8N123 X 88747225-88754785 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 52 "testis: 6.0" "Group enriched" "Detected in some" 7 "Early spermatids: 70.9;Late primary spermatocytes: 74.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 2 CPXM1 "CPX-1, CPX1, CPXM" ENSG00000088882 "Carboxypeptidase X, M14 family member 1" Q96SM3 20 2794074-2800627 "Enzymes, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 107.0" "Cell type enriched" "Detected in some" 5 "Decidual stromal cells: 691.9" "Cell type enriched" "Detected in some" 7 "fibroblast: 13.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "NK-cell: 1.3" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Leukemia: 47.1;Neuroblastoma: 82.6" "Adipose visceral - Adipose progenitor cells, Lung - Fibroblasts_2, Pituitary gland - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "spinal cord: 17.3" "Secreted in other tissues" Enzyme NA NA 1200000 "Cluster 14: Non-specific - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 108: Fibroblasts - ECM organization" "unprognostic (2.74e-2)" "unprognostic (1.23e-1)" "unprognostic (1.45e-1)" "unprognostic (1.19e-1)" "unprognostic (3.07e-1)" "unprognostic (7.47e-2)" "unprognostic (3.04e-1)" "unprognostic (3.14e-2)" "unprognostic (3.23e-2)" "unprognostic (4.85e-2)" "potential prognostic unfavorable (1.10e-5)" "unprognostic (8.26e-2)" "potential prognostic unfavorable (7.70e-5)" "unprognostic (1.32e-2)" "unprognostic (4.31e-1)" "unprognostic (1.16e-2)" "unprognostic (2.80e-3)" "unprognostic (1.80e-1)" "unprognostic (3.02e-1)" "unprognostic (3.73e-2)" "unprognostic (3.12e-2)" "unprognostic (2.32e-2)" "unprognostic (1.32e-1)" "unprognostic (6.08e-2)" "unprognostic (6.06e-2)" "unprognostic (2.46e-3)" "potential prognostic unfavorable (1.92e-4)" "unprognostic (6.65e-2)" "unprognostic (7.80e-2)" "unprognostic (1.20e-3)" "unprognostic (1.55e-1)" CPXM2 "CPX2, UNQ676" ENSG00000121898 "Carboxypeptidase X, M14 family member 2" Q8N436 10 123706207-123940267 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 199.4;choroid plexus: 177.2" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 337.1;Distal convoluted tubule cells: 258.1;Early spermatids: 210.1;Epididymal clear cells: 128.6;Epididymal principal cells: 145.1;Late spermatids: 562.8;Ocular epithelial cells: 94.6;Peritubular myoid cells: 139.7;Pituitary stem cells: 103.4;Retinal pigment epithelial cells: 127.9;Smooth muscle cells: 88.7;Vascular endothelial cells: 129.4" "Cell type enriched" "Detected in many" 4 "choroid plexus epithelial cell: 226.8" "Cancer enriched" "Detected in all" 6 "Kidney Chromophobe (TCGA): 117.9" "Region enriched" "Detected in all" 4 "choroid plexus: 171.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Adrenocortical cancer: 15.2;testis cancer: 25.8" "Colon - Smooth muscle cells, Liver - Hepatic stellate cells, Lung - Fibroblasts_2, Prostate - Smooth muscle cells, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA048375 Uncertain "Secreted - unknown location" "No annotated function" NA NA 1100000 "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 21: Non-specific - Metabolism" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" "HPA048375: " "unprognostic (1.38e-1)" "unprognostic (1.13e-1)" "unprognostic (1.75e-1)" "unprognostic (6.29e-2)" "unprognostic (2.10e-2)" "unprognostic (5.24e-2)" "unprognostic (1.49e-2)" "unprognostic (2.92e-2)" "unprognostic (1.65e-1)" "unprognostic (9.51e-2)" "unprognostic (1.64e-3)" "unprognostic (1.89e-2)" "unprognostic (1.01e-2)" "unprognostic (2.84e-2)" "unprognostic (1.98e-3)" "unprognostic (2.28e-3)" "unprognostic (2.65e-1)" "unprognostic (2.43e-2)" "unprognostic (1.82e-2)" "unprognostic (1.93e-1)" "unprognostic (4.80e-3)" "unprognostic (8.70e-2)" "unprognostic (8.32e-3)" "unprognostic (2.46e-1)" "unprognostic (6.11e-3)" "unprognostic (3.55e-2)" "unprognostic (5.34e-2)" "unprognostic (1.86e-2)" "unprognostic (2.61e-2)" "unprognostic (1.30e-1)" "unprognostic (9.08e-2)" CPZ ENSG00000109625 "Carboxypeptidase Z" Q66K79 4 8592660-8619759 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 145.4" "Cell type enhanced" "Detected in some" "Bergmann glia: 1.0;Fibroblasts: 1.2;Granulosa cells: 1.6;Ovarian stromal cells: 1.9" "Cell type enhanced" "Detected in some" "deep-layer corticothalamic and 6b: 13.4;fibroblast: 28.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Liver - Hepatic stellate cells, Lung - Fibroblasts_2, Skin - Fibroblasts_1, Skin - Fibroblasts_2, Stomach - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA078608 Approved "Plasma membrane" "Secreted to extracellular matrix" Enzyme NA NA "Cluster 75: Ovary - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 94: Gonadal somatic cells - Mixed function" "Plasma membrane" "HPA078608: " "potential prognostic favorable (3.01e-4)" "unprognostic (2.08e-1)" "unprognostic (1.15e-1)" "unprognostic (6.17e-2)" "unprognostic (2.49e-1)" "unprognostic (8.73e-2)" "unprognostic (8.32e-2)" "unprognostic (1.80e-1)" "potential prognostic unfavorable (1.49e-4)" "unprognostic (9.47e-3)" "potential prognostic unfavorable (6.29e-4)" "unprognostic (1.01e-1)" "unprognostic (7.61e-2)" "unprognostic (7.05e-2)" "unprognostic (3.22e-1)" "unprognostic (1.20e-2)" "unprognostic (1.82e-1)" "unprognostic (2.10e-2)" "unprognostic (9.86e-3)" "unprognostic (4.43e-3)" "unprognostic (5.93e-2)" "unprognostic (2.00e-1)" "unprognostic (2.83e-1)" "unprognostic (6.66e-3)" "unprognostic (2.20e-1)" "unprognostic (2.03e-3)" "unprognostic (2.25e-2)" "potential prognostic unfavorable (5.03e-4)" "unprognostic (1.00e-1)" CR1 "CD35, KN" ENSG00000203710 "Complement C3b/C4b receptor 1 (Knops blood group)" P17927 1 207496147-207641765 "Blood group antigen proteins, CD markers, Plasma proteins, Predicted membrane proteins" "Complement pathway, Host-virus interaction, Immunity, Innate immunity" "Blood group antigen, Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 12.4;lymphoid tissue: 25.7" "Cell type enhanced" "Detected in many" "B-cells: 176.8;Kupffer cells: 411.0;Neutrophil progenitors: 136.8;Neutrophils: 1929.7;Podocytes: 706.7" "Cell type enhanced" "Detected in some" "fibroblast: 7.1;leukocyte: 12.1;oligodendrocyte: 8.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 53.8;eosinophil: 17.2;neutrophil: 15.6" "Lineage enriched" "Detected in many" 12 "granulocytes: 53.8" "Group enriched" "Detected in some" 9 "Leukemia: 3.6;lymphoma: 1.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Kidney - Podocytes, Lung - Neutrophils_2, Minor Salivary Gland - Macrophages, Pituitary gland - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in all" "Not detected" "Not detected" "CAB002491, CAB016271, HPA042455, HPA043579, HPA049348" Enhanced Supported "Plasma membrane" NA NA 19000000 "Cluster 20: Non-specific - DNA binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 11: White matter - Signal transduction" "Cluster 55: Lymphoma - Immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 1 "Plasma membrane" "CAB002491: , CAB016271: , HPA042455: , HPA043579: , HPA049348: " "unprognostic (3.19e-1)" "unprognostic (6.73e-3)" "unprognostic (2.40e-1)" "potential prognostic unfavorable (3.09e-4)" "unprognostic (6.59e-2)" "unprognostic (1.20e-3)" "unprognostic (6.21e-2)" "unprognostic (3.54e-2)" "unprognostic (3.00e-1)" "unprognostic (4.72e-2)" "unprognostic (3.66e-2)" "unprognostic (1.23e-1)" "unprognostic (5.13e-2)" "unprognostic (2.49e-2)" CR1L ENSG00000197721 "Complement C3b/C4b receptor 1 like" Q2VPA4 1 207645113-207738416 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 9 "bone marrow: 1.4" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 25.4;Epididymal clear cells: 18.4;Erythrocyte progenitors: 126.2;Erythrocytes: 33.8;Fallopian tube ciliated cells: 16.3;Megakaryocyte progenitors: 17.3;Podocytes: 27.1;Renal collecting duct intercalated cells: 60.5" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in single" 7 "Kidney Chromophobe (TCGA): 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA049348 Approved "Secreted in other tissues" "No annotated function" NA NA "Cluster 15: Bone marrow - Innate immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" "HPA049348: " "unprognostic (1.92e-1)" CR2 "C3DR, CD21" ENSG00000117322 "Complement C3d receptor 2" P20023 1 207453024-207489895 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Complement pathway, Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Receptor" "Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "lymphoid tissue: 163.6" "Cell type enriched" "Detected in some" 4 "B-cells: 56.7" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in many" "Pancreatic Adenocarcinoma (TCGA): 11.2" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "memory B-cell: 17.6;naive B-cell: 20.5" "Lineage enriched" "Detected in many" 8 "B-cells: 20.5" "Group enriched" "Detected in some" 7 "Leukemia: 8.6;lymphoma: 17.5;Myeloma: 8.1" "Minor Salivary Gland - Plasma cells, Spleen - B-cells (Spleen)" "Not detected" "Not detected" "CAB002659, HPA052942, HPA060715" Enhanced NA NA 39000000 "Cluster 18: Non-specific - Translation" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 2 "CAB002659: , HPA052942: , HPA060715: " "unprognostic (4.15e-1)" "potential prognostic favorable (6.18e-4)" "unprognostic (4.34e-2)" "unprognostic (1.62e-1)" "unprognostic (1.96e-1)" "potential prognostic unfavorable (1.38e-4)" "potential prognostic favorable (5.82e-5)" "unprognostic (5.14e-2)" "unprognostic (2.31e-1)" "unprognostic (1.48e-1)" "unprognostic (1.07e-1)" "unprognostic (2.36e-1)" "unprognostic (1.34e-1)" "unprognostic (1.42e-2)" "unprognostic (1.35e-1)" "unprognostic (7.37e-2)" "unprognostic (1.05e-1)" "unprognostic (9.93e-2)" CRABP1 "CRABP, CRABP-I, CRABPI, RBP5" ENSG00000166426 "Cellular retinoic acid binding protein 1" P29762 15 78340353-78348225 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 505.1;thyroid gland: 162.5" "Cell type enriched" "Detected in some" 9 "Müller glia: 3412.2" "Cell type enhanced" "Detected in many" "LAMP5-LHX6 and Chandelier: 21.6;splatter: 26.4" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 272.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Bone cancer: 80.7;breast cancer: 49.6;Neuroblastoma: 180.6" "Colon - Colon enteroendocrine cells" "Group enriched" "Detected in many" 5 "amygdala: 6.4;basal ganglia: 23.4;hypothalamus: 13.3;olfactory bulb: 12.8;pons and medulla: 7.4" "Low region specificity" "Detected in all" HPA017203 Enhanced Supported NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 45: Non-specific - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 11: Muller glia cells - Retinal homeostasis" 3 "HPA017203: " "unprognostic (1.26e-1)" "unprognostic (1.61e-1)" "unprognostic (9.14e-2)" "unprognostic (1.76e-1)" "unprognostic (2.53e-1)" "unprognostic (6.34e-2)" "unprognostic (2.52e-1)" "unprognostic (1.85e-1)" "unprognostic (1.28e-2)" "unprognostic (1.31e-1)" "unprognostic (1.12e-1)" "unprognostic (2.10e-1)" "unprognostic (2.95e-1)" "unprognostic (1.61e-2)" "unprognostic (4.97e-2)" "unprognostic (7.34e-2)" "unprognostic (3.60e-1)" "unprognostic (1.36e-1)" "unprognostic (7.37e-2)" "unprognostic (9.56e-2)" "unprognostic (4.80e-2)" "unprognostic (1.41e-1)" "unprognostic (8.69e-2)" "unprognostic (1.34e-1)" "unprognostic (1.69e-1)" "unprognostic (5.46e-2)" "unprognostic (5.09e-3)" CRABP2 CRABP-II ENSG00000143320 "Cellular retinoic acid binding protein 2" P29373 1 156699606-156705816 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "cervix: 567.4;esophagus: 1174.0;vagina: 589.7" "Group enriched" "Detected in many" 4 "Esophageal apical cells: 1358.3;Esophageal basal cells: 1650.7;Esophageal suprabasal cells: 4577.3" "Cell type enhanced" "Detected in many" "fibroblast: 19.1" "Cancer enhanced" "Detected in all" "Breast Invasive Carcinoma (TCGA): 1007.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "breast cancer: 849.1" "Adipose subcutaneous - Adipose progenitor cells, Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Urothelial cells, Skeletal muscle - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 47.7" "HPA004135, CAB080413" Supported Supported Nucleoplasm,Cytosol NA NA 98000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 85: Squamous epithelial cells - Keratinization" 6 "Nucleoplasm, Cytosol" "CAB080413: , HPA004135: " "potential prognostic favorable (9.69e-5)" "unprognostic (3.81e-3)" "unprognostic (9.09e-2)" "unprognostic (2.06e-1)" "unprognostic (7.67e-2)" "unprognostic (1.89e-1)" "unprognostic (5.15e-2)" "unprognostic (3.46e-1)" "unprognostic (4.79e-2)" "unprognostic (3.73e-2)" "potential prognostic unfavorable (3.54e-8)" "unprognostic (6.78e-2)" "unprognostic (6.31e-2)" "unprognostic (5.36e-3)" "unprognostic (7.54e-3)" "unprognostic (1.63e-1)" "potential prognostic unfavorable (4.06e-5)" "unprognostic (4.69e-2)" "unprognostic (2.56e-1)" "unprognostic (1.54e-1)" "unprognostic (2.89e-2)" "unprognostic (5.09e-3)" "unprognostic (1.09e-2)" "unprognostic (3.97e-2)" "unprognostic (1.05e-2)" "unprognostic (7.94e-2)" "unprognostic (8.47e-2)" "potential prognostic unfavorable (7.02e-4)" "unprognostic (1.55e-1)" "unprognostic (5.33e-3)" "unprognostic (1.64e-1)" CRACD "CRAD, KIAA1211" ENSG00000109265 "Capping protein inhibiting regulator of actin dynamics" Q6ZU35 4 56049098-56330609 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 18.2;testis: 27.4" "Cell type enhanced" "Detected in many" "Corticotrophs: 236.2;Enterocytes: 432.2;Erythrocyte progenitors: 392.9;Hematopoietic stem cells: 224.2;Megakaryocyte progenitors: 422.0;Megakaryocyte-Erythroid progenitors: 679.8;Oligodendrocyte progenitor cells: 228.9;Podocytes: 462.3;Retinal horizontal cells: 288.5;Retinal pigment epithelial cells: 366.6" "Cell type enhanced" "Detected in all" "LAMP5-LHX6 and Chandelier: 862.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 33.0" "Adrenal gland - Fibroblasts, Liver - Hepatic stellate cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043249, HPA048148" Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA 24000 "Cluster 21: Testis - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 5 Nucleoplasm "Golgi apparatus" "HPA043249: , HPA048148: " "unprognostic (3.32e-2)" "unprognostic (1.01e-1)" "unprognostic (2.99e-2)" "unprognostic (1.48e-2)" "unprognostic (3.38e-2)" "unprognostic (3.72e-1)" "unprognostic (1.01e-3)" "potential prognostic unfavorable (6.19e-4)" "unprognostic (4.70e-2)" "unprognostic (1.82e-2)" "unprognostic (1.26e-1)" "unprognostic (2.60e-1)" "unprognostic (3.11e-2)" "unprognostic (1.29e-1)" "unprognostic (9.29e-2)" "unprognostic (1.64e-2)" "unprognostic (2.10e-1)" "potential prognostic favorable (2.65e-4)" "unprognostic (4.07e-1)" "unprognostic (2.60e-2)" "unprognostic (1.84e-1)" "unprognostic (5.03e-2)" "unprognostic (3.69e-2)" CRACDL "C2orf55, KIAA1211L, MGC42367" ENSG00000196872 "CRACD like" Q6NV74 2 98793846-98936259 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.0;epididymis: 29.9" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 164.4;Corticotrophs: 248.2;Epididymal principal cells: 448.6;Fallopian tube ciliated cells: 172.6;Respiratory ciliated cells: 298.4" "Cell type enhanced" "Detected in many" "hippocampal dentate gyrus: 537.6" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in all" 6 "amygdala: 71.5;basal ganglia: 90.8;cerebral cortex: 109.8;hippocampal formation: 107.6;white matter: 55.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Endothelial cells, Liver - Vascular endothelial cells" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "amygdala: 23.2;basal ganglia: 54.1;cerebral cortex: 43.6;hippocampal formation: 64.4;olfactory bulb: 19.9" "HPA051082, HPA061678" Enhanced Approved "Microtubules,Cytokinetic bridge,Centrosome" Yes No "Cluster 22: Epididymis - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 3 "Microtubules, Centrosome" "Cytokinetic bridge" "HPA051082: , HPA061678: " "unprognostic (1.42e-2)" "unprognostic (3.41e-1)" "unprognostic (1.30e-2)" "unprognostic (5.29e-3)" "unprognostic (4.20e-1)" "unprognostic (2.63e-1)" "unprognostic (2.86e-1)" "unprognostic (7.89e-2)" "unprognostic (2.41e-2)" "potential prognostic favorable (2.77e-9)" "unprognostic (1.21e-2)" "unprognostic (1.77e-1)" "unprognostic (2.10e-1)" "unprognostic (2.25e-1)" "unprognostic (1.38e-1)" "unprognostic (9.15e-2)" "unprognostic (3.76e-2)" "unprognostic (2.43e-1)" "unprognostic (9.47e-2)" "unprognostic (1.44e-1)" "unprognostic (1.19e-1)" "unprognostic (7.33e-3)" "unprognostic (1.54e-1)" "unprognostic (1.15e-1)" "unprognostic (7.48e-2)" "unprognostic (7.48e-2)" "unprognostic (7.64e-3)" "unprognostic (2.14e-2)" CRACR2A "EFCAB4B, MGC4266, RAB46" ENSG00000130038 "Calcium release activated channel regulator 2A" Q9BSW2 12 3606633-3764819 "Predicted intracellular proteins" "Adaptive immunity, Calcium transport, Immunity, Ion transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 16.0;intestine: 12.7;salivary gland: 36.4" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 129.1;Goblet cells: 234.3;Innate lymphoid cells: 113.1;Lacrimal acinar cells: 197.5;Paneth cells: 104.4;Prostatic glandular cells: 89.9;Salivary acinar cells: 277.1;Salivary duct cells: 115.3;Salivary ionocytes: 382.5" "Cell type enhanced" "Detected in many" "leukocyte: 81.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 16.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA038686 Enhanced NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 60: Stomach - Digestion" "Cluster 8: Immune cells - Immune response" "Cluster 72: Neuronal - Signal transduction" "Cluster 70: Intestinal goblet cells - Mucin production" 34 "HPA038686: " "unprognostic (3.78e-2)" "unprognostic (3.38e-1)" "unprognostic (2.86e-2)" "unprognostic (2.41e-2)" "unprognostic (2.95e-1)" "unprognostic (2.84e-1)" "unprognostic (1.11e-2)" "unprognostic (1.30e-1)" "unprognostic (1.74e-1)" "unprognostic (1.74e-1)" "unprognostic (5.08e-1)" "unprognostic (1.06e-1)" "unprognostic (3.57e-2)" "unprognostic (2.61e-1)" "potential prognostic unfavorable (6.48e-4)" "unprognostic (3.26e-1)" "unprognostic (5.94e-3)" "unprognostic (2.45e-1)" "unprognostic (3.64e-2)" "unprognostic (2.56e-1)" "unprognostic (8.14e-3)" "unprognostic (9.12e-2)" "unprognostic (1.84e-1)" CRACR2B "EFCAB4A, MGC45840" ENSG00000177685 "Calcium release activated channel regulator 2B" Q8N4Y2 11 826144-831991 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 136.4;salivary gland: 210.1" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 207.2;Breast lactating cells: 240.6;Breast secretory cells: 183.5;Foveolar cells: 129.9;Goblet cells: 148.3;Lacrimal acinar cells: 106.0;Mucous neck cells: 97.9;Prostatic club cells: 146.3;Respiratory deuterosomal cells: 91.2;Respiratory secretory cells: 125.9;Salivary acinar cells: 157.6;Submucosal glandular cells: 130.7" "Cell type enhanced" "Detected in many" "endothelial cell: 20.7;pericyte: 12.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 3.4;eosinophil: 3.7;memory B-cell: 3.9;naive B-cell: 3.0;NK-cell: 1.7" "Group enriched" "Detected in many" 6 "B-cells: 3.9;granulocytes: 3.7;NK-cells: 1.7" "Cancer enhanced" "Detected in many" "breast cancer: 42.9" "Breast - Breast glandular cells, Liver - Vascular endothelial cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046217 Approved NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 60: Stomach - Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 70: Intestinal goblet cells - Mucin production" 1 "HPA046217: " "unprognostic (3.30e-3)" "unprognostic (2.56e-1)" "unprognostic (8.14e-2)" "unprognostic (1.41e-2)" "unprognostic (1.74e-1)" "unprognostic (1.15e-2)" "unprognostic (2.07e-3)" "unprognostic (2.11e-1)" "unprognostic (1.48e-2)" "unprognostic (4.42e-3)" "potential prognostic favorable (1.67e-9)" "unprognostic (5.64e-2)" "unprognostic (1.54e-1)" "unprognostic (1.30e-1)" "unprognostic (1.04e-3)" "unprognostic (4.27e-2)" "unprognostic (2.18e-2)" "unprognostic (9.44e-2)" "unprognostic (2.96e-2)" "unprognostic (1.45e-1)" "unprognostic (1.76e-2)" "unprognostic (7.02e-2)" "unprognostic (2.12e-3)" "potential prognostic favorable (7.28e-4)" "unprognostic (1.64e-1)" "unprognostic (2.97e-1)" "unprognostic (3.99e-2)" CRADD RAIDD ENSG00000169372 "CASP2 and RIPK1 domain containing adaptor with death domain" P78560 12 93677375-93894840 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" Apoptosis "Cancer-related genes, Disease variant, Intellectual disability, Lissencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005337 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 13 Cytosol Nucleoplasm "CAB005337: " "unprognostic (1.05e-1)" "unprognostic (1.16e-2)" "unprognostic (1.57e-1)" "unprognostic (1.36e-3)" "unprognostic (9.02e-2)" "unprognostic (1.20e-2)" "unprognostic (1.86e-1)" "unprognostic (2.63e-2)" "unprognostic (1.50e-1)" "unprognostic (7.91e-2)" "potential prognostic favorable (8.21e-12)" "unprognostic (2.10e-2)" "potential prognostic favorable (6.41e-4)" "unprognostic (9.44e-2)" "unprognostic (1.36e-1)" "unprognostic (3.42e-1)" "unprognostic (3.00e-1)" "unprognostic (9.01e-3)" "unprognostic (1.37e-1)" "unprognostic (2.57e-1)" "unprognostic (2.85e-3)" "unprognostic (5.59e-2)" "unprognostic (1.32e-1)" "unprognostic (5.24e-2)" "unprognostic (2.67e-1)" "unprognostic (7.68e-3)" "unprognostic (2.14e-1)" "unprognostic (4.89e-2)" "unprognostic (2.39e-1)" "unprognostic (3.45e-1)" "unprognostic (1.99e-1)" CRAMP1 "CRAMP1L, KIAA1426" ENSG00000007545 "Cramped chromatin regulator homolog 1" Q96RY5 16 1612337-1677908 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Lactotrophs: 14.2;Somatotrophs: 16.3;Thyrotrophs: 15.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041752 Uncertain Approved Nucleoplasm,Nucleoli,Cytosol No No "Cluster 67: Testis - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 54: Non-specific - Transcription" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 3 Nucleoplasm "Nucleoli, Cytosol" "HPA041752: " "unprognostic (2.14e-2)" "unprognostic (3.42e-2)" "unprognostic (4.51e-3)" "unprognostic (2.30e-1)" "unprognostic (9.21e-2)" "unprognostic (5.59e-2)" "potential prognostic favorable (9.65e-4)" "unprognostic (1.72e-3)" "unprognostic (4.67e-1)" "unprognostic (2.36e-1)" "unprognostic (2.74e-3)" "unprognostic (1.80e-1)" "unprognostic (8.72e-3)" "unprognostic (4.25e-2)" "unprognostic (2.32e-2)" "unprognostic (3.73e-2)" "unprognostic (1.66e-2)" "unprognostic (2.66e-2)" "unprognostic (2.15e-1)" "unprognostic (2.97e-2)" "unprognostic (6.83e-3)" "unprognostic (1.20e-1)" "unprognostic (2.01e-3)" "unprognostic (2.69e-1)" "unprognostic (9.93e-2)" "unprognostic (1.34e-2)" "unprognostic (7.80e-2)" "unprognostic (4.01e-2)" "unprognostic (1.78e-2)" CRAT CAT1 ENSG00000095321 "Carnitine O-acetyltransferase" P43155 9 129094142-129111189 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Transport" "Acyltransferase, Transferase" Neurodegeneration "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 206.8;tongue: 188.1" "Cell type enhanced" "Detected in many" "Early spermatids: 191.2;Enterocytes: 142.3;Esophageal apical cells: 123.9;Late primary spermatocytes: 299.2;Late spermatids: 977.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Skin - Sebaceous gland cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019230, HPA020260, HPA022815" Enhanced Approved "Golgi apparatus,Cytosol" NA NA 4300 "Cluster 33: Non-specific - ATP binding" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 45: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 1 "Golgi apparatus, Cytosol" "HPA019230: , HPA020260: , HPA022815: " "potential prognostic unfavorable (4.96e-4)" "unprognostic (7.64e-2)" "unprognostic (1.88e-1)" "unprognostic (4.01e-2)" "unprognostic (1.90e-1)" "unprognostic (2.41e-1)" "unprognostic (8.64e-2)" "unprognostic (4.24e-1)" "unprognostic (6.85e-2)" "unprognostic (9.65e-2)" "potential prognostic favorable (9.16e-7)" "unprognostic (2.59e-2)" "potential prognostic favorable (8.15e-5)" "unprognostic (1.88e-1)" "unprognostic (1.28e-1)" "unprognostic (5.54e-2)" "unprognostic (1.70e-3)" "unprognostic (3.18e-1)" "unprognostic (1.27e-2)" "unprognostic (5.46e-2)" "unprognostic (2.67e-1)" "potential prognostic favorable (3.62e-4)" "unprognostic (6.92e-2)" "unprognostic (1.44e-1)" "unprognostic (4.67e-2)" "unprognostic (2.25e-3)" "unprognostic (9.58e-2)" "unprognostic (3.16e-2)" "unprognostic (1.03e-1)" "unprognostic (1.56e-2)" "unprognostic (2.33e-3)" CRB1 "LCA8, RP12" ENSG00000134376 "Crumbs cell polarity complex component 1" P82279 1 197268204-197478455 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Disease variant, Leber congenital amaurosis, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "retina: 69.2" "Cell type enhanced" "Detected in many" "Astrocytes: 465.6;Bergmann glia: 440.4;Cone photoreceptor cells: 254.6;Corticotrophs: 306.5;Ependymal cells: 1470.5;Müller glia: 594.7;Oligodendrocyte progenitor cells: 297.4;Oligodendrocytes: 297.7;Rod photoreceptor cells: 337.3;Sertoli cells: 168.2" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 1028.8;ependymal cell: 1432.7" "Cancer enriched" "Detected in some" 11 "Glioblastoma Multiforme (TCGA): 19.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 28 "basophil: 7.8" "Lineage enriched" "Detected in single" 28 "granulocytes: 7.8" "Group enriched" "Detected in some" 5 "cervical cancer: 4.7;Sarcoma: 4.6" "Kidney - Ascending Loop of Henle cells, Pituitary gland - Corticotropes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA061250, HPA063127" Approved Approved Vesicles "Secreted in brain" "No annotated function" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 7: Liver cancer - Metabolism" "Cluster 34: Ciliated cells - Cilia assembly & function" 7 Vesicles "HPA061250: , HPA063127: " "unprognostic (5.68e-2)" "unprognostic (6.16e-3)" "unprognostic (4.83e-2)" CRB2 "FLJ16786, FLJ38464" ENSG00000148204 "Crumbs cell polarity complex component 2" Q5IJ48 9 123356170-123380324 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Gastrulation, Sensory transduction, Vision" "Developmental protein" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.8;choroid plexus: 3.7;kidney: 5.3;retina: 7.5" "Cell type enhanced" "Detected in some" "Astrocytes: 68.2;Bergmann glia: 74.5;Cone photoreceptor cells: 49.7;Ependymal cells: 102.6;Late spermatids: 29.2;Mesothelial cells: 38.3;Oligodendrocytes: 32.1;Podocytes: 160.5;Retinal bipolar cells: 31.2;Rod photoreceptor cells: 94.8" "Cell type enhanced" "Detected in many" "astrocyte: 89.2;Bergmann glia: 66.1;ependymal cell: 128.1" "Group enriched" "Detected in some" 7 "Glioblastoma Multiforme (TCGA): 16.5;Ovary Serous Cystadenocarcinoma (TCGA): 7.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 4.8" "Adipose visceral - Mesothelial cells, Kidney - Podocytes, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043674 Approved Supported "Intracellular and membrane" "Developmental protein" NA NA 87000 "Cluster 36: Brain & Liver - Signaling" "Cluster 39: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 28: Astrocytes - Homeostasis & neuron support" "HPA043674: " "unprognostic (2.24e-1)" "unprognostic (1.23e-1)" "unprognostic (7.99e-3)" "unprognostic (1.84e-1)" "unprognostic (1.53e-2)" "unprognostic (6.63e-2)" "unprognostic (8.69e-3)" "unprognostic (8.92e-2)" "unprognostic (6.60e-2)" "unprognostic (5.35e-2)" "unprognostic (1.50e-1)" CRB3 MGC17303 ENSG00000130545 "Crumbs cell polarity complex component 3" Q9BUF7 19 6463777-6467221 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 52.7" "Cell type enhanced" "Detected in many" "Colonocytes: 131.8;Epididymal efferent duct absorptive cells: 103.1;Esophageal apical cells: 692.1;Esophageal suprabasal cells: 173.2;Ocular epithelial cells: 103.9;Suprabasal keratinocytes: 108.5" "Cell type enhanced" "Detected in single" "choroid plexus epithelial cell: 1.1" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "choroid plexus: 14.1" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 9.2" "Group enriched" "Detected in many" 21 "B-cells: 3.1;T-cells: 9.2" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Breast - Breast glandular cells, Lung - Alveolar cells type 2, Pituitary gland - Somatotropes, Stomach - Gastric mucous cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA013835 Enhanced Supported "Cell Junctions" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 60: Stomach - Digestion" "Cluster 5: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 7 "Cell Junctions" "HPA013835: " "unprognostic (3.69e-2)" "unprognostic (3.69e-2)" "unprognostic (5.87e-2)" "unprognostic (3.55e-1)" "unprognostic (6.42e-3)" "unprognostic (1.25e-1)" "unprognostic (6.74e-2)" "unprognostic (8.47e-2)" "potential prognostic favorable (3.33e-16)" "unprognostic (1.83e-3)" "unprognostic (1.81e-3)" "unprognostic (1.47e-1)" "unprognostic (1.53e-1)" "unprognostic (2.25e-2)" "unprognostic (2.21e-1)" "unprognostic (2.08e-1)" "unprognostic (1.65e-1)" "unprognostic (6.08e-2)" "unprognostic (5.85e-3)" "unprognostic (2.41e-1)" "unprognostic (5.83e-3)" "unprognostic (4.66e-1)" "unprognostic (4.50e-2)" "unprognostic (2.27e-1)" "unprognostic (1.45e-1)" "unprognostic (1.96e-2)" "unprognostic (2.54e-1)" "unprognostic (4.42e-2)" "unprognostic (1.87e-2)" CRBN "MRT2, MRT2A" ENSG00000113851 Cereblon Q96SW2 3 3144628-3179727 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Transporters" "Ubl conjugation pathway" "Disease variant, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 340.3;Oocytes: 350.0;Platelets: 337.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 309.4" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045910 Approved NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 47: Platelets - Hemostasis" 56 "HPA045910: " "unprognostic (1.75e-2)" "unprognostic (5.90e-2)" "unprognostic (2.59e-1)" "unprognostic (9.67e-2)" "unprognostic (1.30e-1)" "unprognostic (2.48e-2)" "unprognostic (1.75e-2)" "unprognostic (7.53e-2)" "unprognostic (2.46e-1)" "unprognostic (8.96e-3)" "validated prognostic favorable (1.75e-7)" "validated prognostic favorable (1.06e-4)" "unprognostic (1.57e-2)" "unprognostic (1.53e-1)" "unprognostic (9.76e-3)" "unprognostic (1.05e-3)" "unprognostic (9.74e-2)" "unprognostic (7.73e-2)" "unprognostic (1.22e-1)" "unprognostic (3.16e-1)" "unprognostic (2.14e-3)" "unprognostic (1.67e-1)" "unprognostic (1.46e-2)" "unprognostic (1.41e-1)" "potential prognostic favorable (1.04e-5)" "unprognostic (2.82e-3)" "unprognostic (1.72e-1)" "unprognostic (1.60e-1)" "unprognostic (1.90e-1)" "unprognostic (2.32e-1)" "unprognostic (3.06e-1)" CRCP "C17, CGRP-RCP, POLR3I, RCP, RCP9" ENSG00000241258 "CGRP receptor component" O75575 7 66114604-66154568 "Essential proteins, Predicted intracellular proteins, RNA polymerase related proteins" "Antiviral defense, Immunity, Innate immunity, Transcription" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006883, HPA007216" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 32: Basophils - Transcription" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 39: Non-specific - Transcription" "Cluster 22: Non-specific - Basic cellular functions" 50 Nucleoplasm "Plasma membrane" "HPA006883: , HPA007216: " "unprognostic (6.87e-2)" "unprognostic (1.51e-3)" "unprognostic (5.95e-2)" "unprognostic (5.23e-3)" "unprognostic (3.22e-1)" "unprognostic (4.18e-1)" "unprognostic (2.52e-2)" "unprognostic (5.70e-3)" "unprognostic (1.37e-1)" "potential prognostic unfavorable (9.72e-5)" "potential prognostic favorable (3.45e-8)" "unprognostic (1.94e-3)" "unprognostic (2.92e-1)" "unprognostic (1.44e-2)" "unprognostic (1.05e-1)" "unprognostic (9.37e-3)" "unprognostic (2.64e-2)" "unprognostic (3.03e-1)" "unprognostic (2.39e-2)" "unprognostic (1.53e-3)" "unprognostic (4.46e-2)" "unprognostic (7.35e-2)" "unprognostic (4.01e-2)" "unprognostic (2.80e-1)" "unprognostic (1.73e-1)" "unprognostic (3.93e-2)" "unprognostic (4.67e-3)" "unprognostic (1.99e-1)" "unprognostic (1.52e-1)" "unprognostic (7.20e-2)" "unprognostic (3.37e-1)" CRCT1 "C1orf42, NICE-1" ENSG00000169509 "Cysteine rich C-terminal 1" Q9UGL9 1 152514482-152516008 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 641.4;esophagus: 1886.5;vagina: 806.6" "Cell type enriched" "Detected in some" 126 "Esophageal apical cells: 83038.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 106.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 6.6;cervical cancer: 3.7;head and neck cancer: 5.5" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 84: Apical squamous epithelium - Cornification" 46 "unprognostic (2.24e-3)" "unprognostic (1.51e-1)" "unprognostic (1.30e-1)" "unprognostic (2.53e-1)" "potential prognostic unfavorable (7.98e-4)" "unprognostic (2.16e-3)" "unprognostic (2.46e-1)" "unprognostic (8.15e-3)" CREB1 ENSG00000118260 "CAMP responsive element binding protein 1" P16220 2 207529737-207605988 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Differentiation, Host-virus interaction, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 620.7;Neutrophils: 618.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003803, HPA019150, HPA072073" Supported Enhanced "Nucleoplasm,Centrosome,Basal body,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 54 Nucleoplasm "Centrosome, Basal body, Cytosol" "CAB003803: , HPA019150: , HPA072073: " "unprognostic (4.20e-2)" "unprognostic (5.53e-2)" "unprognostic (5.86e-2)" "unprognostic (6.46e-2)" "unprognostic (2.84e-2)" "unprognostic (5.58e-2)" "unprognostic (2.19e-1)" "unprognostic (2.75e-2)" "unprognostic (3.20e-1)" "unprognostic (1.33e-2)" "potential prognostic favorable (8.47e-6)" "unprognostic (3.05e-3)" "unprognostic (1.46e-2)" "unprognostic (1.81e-3)" "unprognostic (5.41e-2)" "unprognostic (2.83e-1)" "unprognostic (1.33e-3)" "unprognostic (1.89e-1)" "unprognostic (2.11e-2)" "unprognostic (8.02e-2)" "unprognostic (3.64e-3)" "unprognostic (3.11e-2)" "potential prognostic unfavorable (1.09e-4)" "unprognostic (4.12e-2)" "unprognostic (2.47e-2)" "unprognostic (1.34e-1)" "unprognostic (3.33e-2)" "unprognostic (1.69e-2)" "unprognostic (1.19e-1)" "unprognostic (2.92e-2)" "unprognostic (1.07e-1)" CREB3 "Luman, LZIP, sLZIP" ENSG00000107175 "CAMP responsive element binding protein 3" O43889 9 35732598-35736999 "Predicted membrane proteins, Transcription factors" "Chemotaxis, Host-virus interaction, Transcription, Transcription regulation, Unfolded protein response" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 192.7;Late spermatids: 692.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Prostate glandular cells, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030978, HPA077421" Supported "Vesicles,Plasma membrane,Primary cilium,Primary cilium tip,Primary cilium transition zone,Centrosome,Basal body,Cytosol" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 48 Cytosol "Vesicles, Plasma membrane, Primary cilium, Primary cilium tip, Primary cilium transition zone, Centrosome, Basal body" "HPA030978: , HPA077421: " "unprognostic (1.24e-2)" "unprognostic (9.33e-2)" "unprognostic (3.81e-1)" "unprognostic (1.35e-1)" "unprognostic (2.59e-1)" "unprognostic (8.59e-2)" "unprognostic (1.90e-1)" "unprognostic (2.38e-1)" "unprognostic (8.44e-3)" "unprognostic (1.40e-2)" "potential prognostic favorable (2.54e-6)" "unprognostic (1.79e-1)" "unprognostic (1.39e-2)" "potential prognostic unfavorable (5.80e-4)" "unprognostic (5.56e-3)" "unprognostic (2.15e-2)" "potential prognostic unfavorable (2.08e-6)" "unprognostic (2.42e-1)" "unprognostic (2.77e-1)" "unprognostic (1.25e-2)" "unprognostic (2.82e-1)" "unprognostic (1.73e-1)" "unprognostic (8.65e-2)" "unprognostic (3.18e-1)" "unprognostic (2.33e-2)" "unprognostic (6.62e-2)" "unprognostic (1.35e-1)" "unprognostic (1.12e-1)" "unprognostic (9.39e-2)" "unprognostic (2.93e-1)" "unprognostic (3.47e-1)" CREB3L1 OASIS ENSG00000157613 "CAMP responsive element binding protein 3 like 1" Q96BA8 11 46277662-46321409 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation, Unfolded protein response" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 126.4;salivary gland: 79.8" "Cell type enhanced" "Detected in many" "Breast lactating cells: 606.7;Endometrial luminal cells: 193.9;Foveolar cells: 132.0;Gastric chief cells: 120.1;Goblet cells: 406.4;Mucous neck cells: 158.1;Pancreatic acinar cells: 190.5;Prostatic club cells: 236.2;Respiratory secretory cells: 182.3" "Cell type enhanced" "Detected in many" "deep-layer corticothalamic and 6b: 21.2;oligodendrocyte precursor cell: 51.2" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 182.3;Stomach Adenocarcinoma (TCGA): 176.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Cardiomyocytes, Minor Salivary Gland - Minor salivary glandular cells, Skin - Fibroblasts_1, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024069, CAB026151, HPA062116" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 60: Stomach - Digestion" "Cluster 14: Neurons - Synaptic function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 70: Intestinal goblet cells - Mucin production" 172 Nucleoplasm Cytosol "CAB026151: , HPA024069: , HPA062116: " "unprognostic (3.69e-2)" "unprognostic (9.07e-3)" "unprognostic (2.27e-2)" "unprognostic (2.63e-2)" "unprognostic (2.25e-1)" "unprognostic (4.06e-2)" "unprognostic (3.42e-3)" "unprognostic (5.87e-3)" "unprognostic (3.52e-1)" "unprognostic (2.65e-2)" "unprognostic (1.29e-2)" "unprognostic (1.04e-1)" "potential prognostic unfavorable (5.72e-6)" "unprognostic (3.40e-2)" "unprognostic (1.71e-1)" "unprognostic (1.89e-2)" "unprognostic (1.59e-1)" "potential prognostic unfavorable (2.25e-4)" "unprognostic (2.66e-1)" "unprognostic (2.81e-2)" "unprognostic (6.74e-2)" "unprognostic (2.84e-2)" "unprognostic (1.68e-2)" "unprognostic (4.33e-1)" "unprognostic (1.80e-1)" "potential prognostic unfavorable (8.14e-4)" "unprognostic (7.61e-2)" "unprognostic (1.41e-1)" "unprognostic (3.27e-1)" "potential prognostic unfavorable (4.16e-4)" "unprognostic (2.25e-1)" CREB3L2 "BBF2H7, TCAG_1951439" ENSG00000182158 "CAMP responsive element binding protein 3 like 2" Q70SY1 7 137874979-138002086 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation, Unfolded protein response" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 341.8;Plasma cells: 698.4;Syncytiotrophoblasts: 325.1" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 246.4;fibroblast: 202.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Peritubular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015068, HPA015534" Enhanced Supported "Nucleoplasm,Endoplasmic reticulum" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 36: Choroid plexus - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 44: Plasma cells - Antibody production & secretion" "Nucleoplasm, Endoplasmic reticulum" "HPA015068: , HPA015534: " "unprognostic (2.42e-2)" "unprognostic (1.55e-1)" "unprognostic (1.61e-2)" "unprognostic (4.62e-3)" "unprognostic (1.34e-1)" "unprognostic (6.18e-2)" "unprognostic (1.01e-1)" "unprognostic (2.11e-2)" "unprognostic (2.07e-1)" "unprognostic (1.14e-1)" "potential prognostic favorable (4.84e-4)" "unprognostic (8.75e-2)" "unprognostic (1.04e-1)" "unprognostic (8.39e-3)" "unprognostic (1.08e-2)" "unprognostic (1.51e-1)" "unprognostic (2.00e-1)" "unprognostic (1.14e-1)" "unprognostic (1.86e-1)" "unprognostic (4.11e-2)" "unprognostic (1.24e-2)" "unprognostic (2.52e-1)" "unprognostic (1.24e-1)" "unprognostic (2.57e-1)" "unprognostic (1.98e-2)" "unprognostic (5.09e-3)" "unprognostic (2.55e-1)" "unprognostic (9.63e-3)" "unprognostic (2.69e-1)" "unprognostic (7.05e-3)" "unprognostic (7.11e-2)" CREB3L3 "CREB-H, CREBH" ENSG00000060566 "CAMP responsive element binding protein 3 like 3" Q68CJ9 19 4153631-4173054 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation, Unfolded protein response" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 74 "intestine: 242.2;liver: 381.3" "Group enriched" "Detected in some" 25 "Enterocytes: 460.1;Hepatocytes: 129.5" "Low cell type specificity" "Detected in some" "Cancer enriched" "Detected in some" 10 "Liver Hepatocellular Carcinoma (TCGA): 135.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 8.0;liver cancer: 21.5;pancreatic cancer: 8.7" "Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA040671, HPA056228" Enhanced NA NA 37000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 18: Liver cancer - Metabolism" "Cluster 1: Enterocytes - Absorption and Digestion" 20 "HPA040671: , HPA056228: " "unprognostic (5.59e-2)" "potential prognostic favorable (4.90e-4)" "unprognostic (5.89e-3)" "unprognostic (5.26e-2)" "unprognostic (2.52e-1)" "unprognostic (9.31e-2)" "unprognostic (4.94e-3)" "unprognostic (9.10e-2)" "unprognostic (1.86e-3)" "unprognostic (2.04e-1)" CREB3L4 "AIbZIP, ATCE1, CREB3, CREB4, hJAL" ENSG00000143578 "CAMP responsive element binding protein 3 like 4" Q8TEY5 1 153967534-153974361 "Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation, Unfolded protein response" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "prostate: 99.7" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 60.4;Gastric chief cells: 73.2;Goblet cells: 61.9;Mucous neck cells: 55.0;Prostatic glandular cells: 153.7" "Cell type enhanced" "Detected in many" "ependymal cell: 10.4" "Group enriched" "Detected in all" 4 "Breast Invasive Carcinoma (TCGA): 134.6;Prostate Adenocarcinoma (TCGA): 279.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "breast cancer: 111.8" "Breast - Breast glandular cells, Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA038122 Enhanced Approved "Nucleoplasm,Nuclear membrane,Mitochondria" No No "Cluster 32: Basophils - Transcription" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 2 "Nucleoplasm, Nuclear membrane" Mitochondria "HPA038122: " "unprognostic (9.18e-2)" "unprognostic (9.43e-2)" "unprognostic (2.11e-2)" "unprognostic (2.02e-1)" "unprognostic (8.38e-3)" "unprognostic (3.38e-2)" "unprognostic (2.34e-1)" "unprognostic (3.42e-3)" "unprognostic (1.08e-1)" "unprognostic (1.94e-1)" "unprognostic (2.33e-3)" "unprognostic (4.79e-3)" "unprognostic (1.44e-1)" "unprognostic (1.09e-2)" "unprognostic (8.33e-2)" "unprognostic (1.40e-1)" "unprognostic (2.97e-1)" "unprognostic (7.09e-2)" "unprognostic (9.58e-2)" "unprognostic (6.71e-2)" "unprognostic (1.50e-1)" "unprognostic (3.10e-2)" "unprognostic (1.16e-1)" "unprognostic (1.56e-1)" "unprognostic (2.10e-1)" "potential prognostic unfavorable (3.18e-4)" "unprognostic (8.30e-2)" "unprognostic (1.52e-1)" "unprognostic (1.11e-1)" "unprognostic (7.54e-3)" "unprognostic (6.60e-2)" CREB5 "CRE-BPA, H_GS165L15.1" ENSG00000146592 "CAMP responsive element binding protein 5" Q02930 7 28299321-28825894 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibro-adipogenic progenitors: 504.1;Neutrophils: 2648.5;Oligodendrocytes: 878.6;Pancreatic duct cells: 1172.1;Schwann cells: 495.0" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 414.2;oligodendrocyte: 998.9" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 25.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 199.9" "Lineage enriched" "Detected in many" 7 "granulocytes: 199.9" "Low cancer specificity" "Detected in many" "Pancreas - Ductal cells, Skin - Outer root sheath cells, Spleen - Neutrophils_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA050020, HPA061622" Approved "Nucleoplasm,Nuclear bodies,Vesicles,Plasma membrane" NA Yes "Cluster 21: Neutrophils - Unknown function" "Cluster 73: Brain - Neuronal signaling" "Cluster 11: White matter - Signal transduction" "Cluster 15: Kidney cancer - Membrane components" "Cluster 24: Neutrophils - Innate immunity signal integration" 11 Nucleoplasm "Nuclear bodies, Vesicles, Plasma membrane" "HPA050020: , HPA061622: " "unprognostic (3.23e-2)" "unprognostic (3.08e-2)" "unprognostic (1.84e-1)" "unprognostic (1.55e-2)" "unprognostic (7.05e-2)" "unprognostic (2.20e-1)" "unprognostic (1.47e-1)" "unprognostic (7.16e-2)" "unprognostic (7.66e-2)" "unprognostic (2.85e-1)" "unprognostic (6.00e-3)" "unprognostic (2.14e-1)" "unprognostic (2.69e-1)" "unprognostic (2.82e-1)" "unprognostic (3.13e-2)" "unprognostic (2.51e-3)" "unprognostic (2.50e-2)" "unprognostic (5.45e-2)" "unprognostic (1.95e-1)" "unprognostic (1.57e-2)" "unprognostic (6.37e-2)" "unprognostic (2.09e-3)" "unprognostic (5.37e-2)" "unprognostic (1.76e-2)" "unprognostic (3.36e-1)" "unprognostic (4.77e-2)" "unprognostic (2.81e-1)" "unprognostic (1.54e-1)" "unprognostic (2.91e-2)" CREBBP "CBP, KAT3A, RSTS, RTS" ENSG00000005339 "CREB binding protein" Q92793 16 3725054-3880713 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Host-virus interaction, Transcription, Transcription regulation" "Activator, Acyltransferase, Transferase" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 1399.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004212, HPA055861" Supported Enhanced "Nucleoplasm,Nuclear bodies" No No "Cluster 20: Non-specific - DNA binding" "Cluster 61: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 54: Non-specific - Transcription" "Cluster 24: Neutrophils - Innate immunity signal integration" 260 "Nucleoplasm, Nuclear bodies" "CAB004212: , HPA055861: " "unprognostic (3.44e-3)" "unprognostic (1.50e-1)" "unprognostic (2.44e-1)" "unprognostic (6.42e-2)" "unprognostic (2.35e-1)" "unprognostic (2.08e-2)" "unprognostic (2.99e-1)" "unprognostic (1.29e-1)" "unprognostic (7.44e-2)" "unprognostic (5.48e-2)" "validated prognostic favorable (1.90e-6)" "validated prognostic favorable (7.46e-4)" "unprognostic (2.43e-1)" "unprognostic (3.46e-3)" "unprognostic (3.97e-1)" "unprognostic (2.14e-1)" "unprognostic (6.45e-2)" "unprognostic (2.39e-1)" "unprognostic (4.87e-2)" "unprognostic (8.24e-2)" "unprognostic (1.16e-1)" "unprognostic (1.22e-1)" "unprognostic (1.20e-3)" "unprognostic (1.49e-1)" "unprognostic (2.65e-2)" "unprognostic (3.10e-2)" "unprognostic (7.99e-2)" "unprognostic (7.88e-2)" "unprognostic (1.67e-1)" "unprognostic (7.22e-3)" "unprognostic (8.97e-2)" CREBL2 ENSG00000111269 "CAMP responsive element binding protein like 2" O60519 12 12611827-12645108 "Predicted intracellular proteins, Transcription factors" "Cell cycle, Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 123.4" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 169.3;Kupffer cells: 242.9" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 150.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043738 Uncertain Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 38: Non-specific - Transcription" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 6 Mitochondria "Nucleoplasm, Cytosol" "HPA043738: " "unprognostic (7.32e-3)" "unprognostic (4.04e-1)" "unprognostic (1.27e-1)" "unprognostic (3.24e-1)" "unprognostic (1.65e-1)" "unprognostic (1.60e-2)" "unprognostic (1.30e-1)" "unprognostic (2.32e-2)" "unprognostic (1.81e-1)" "unprognostic (3.02e-3)" "validated prognostic favorable (1.21e-10)" "validated prognostic favorable (5.27e-4)" "unprognostic (3.23e-2)" "unprognostic (3.97e-2)" "unprognostic (2.39e-1)" "unprognostic (2.18e-1)" "unprognostic (9.71e-2)" "unprognostic (1.93e-2)" "unprognostic (4.66e-2)" "unprognostic (5.72e-3)" "unprognostic (3.88e-2)" "unprognostic (3.54e-2)" "unprognostic (1.44e-1)" "unprognostic (1.66e-1)" "unprognostic (4.91e-2)" "unprognostic (3.41e-1)" "unprognostic (2.40e-1)" "unprognostic (8.86e-2)" "unprognostic (1.81e-1)" "unprognostic (2.28e-1)" "unprognostic (1.22e-1)" CREBRF "C5orf41, LRF" ENSG00000164463 "CREB3 regulatory factor" Q8IUR6 5 173056352-173139284 "Predicted intracellular proteins" "Stress response, Transcription, Transcription regulation, Transport, Unfolded protein response" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 64.3" "Cell type enriched" "Detected in many" 4 "Neutrophils: 1311.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 22.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015329 Supported Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 15: Bone marrow - Innate immune response" "Cluster 25: Non-specific - Transcription" "Cluster 47: Leukemia - Hemostasis" "Cluster 24: Neutrophils - Innate immunity signal integration" 3 Nucleoplasm "HPA015329: " "potential prognostic favorable (5.40e-5)" "unprognostic (1.73e-1)" "unprognostic (2.33e-2)" "unprognostic (1.84e-1)" "unprognostic (7.50e-2)" "unprognostic (2.14e-1)" "unprognostic (2.54e-1)" "unprognostic (6.49e-3)" "unprognostic (1.37e-1)" "validated prognostic favorable (1.99e-9)" "validated prognostic favorable (2.19e-5)" "unprognostic (1.05e-1)" "unprognostic (3.39e-1)" "unprognostic (1.93e-3)" "unprognostic (3.44e-2)" "unprognostic (5.21e-2)" "unprognostic (1.66e-1)" "unprognostic (2.19e-2)" "potential prognostic unfavorable (4.94e-5)" "unprognostic (2.01e-1)" "unprognostic (5.19e-2)" "unprognostic (1.61e-2)" "unprognostic (1.05e-2)" "unprognostic (1.66e-1)" "unprognostic (4.64e-2)" "unprognostic (1.15e-1)" "unprognostic (2.62e-1)" "unprognostic (7.11e-2)" "unprognostic (2.06e-1)" CREBZF ZF ENSG00000137504 "CREB/ATF bZIP transcription factor" Q9NS37 11 85657742-85682908 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021526, HPA063652" Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 49: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 19 "Nucleoplasm, Mitochondria" "HPA021526: , HPA063652: " "unprognostic (2.36e-2)" "unprognostic (1.21e-3)" "unprognostic (7.02e-2)" "unprognostic (1.39e-1)" "unprognostic (8.12e-2)" "unprognostic (3.59e-1)" "unprognostic (7.85e-2)" "unprognostic (5.45e-3)" "unprognostic (5.74e-2)" "unprognostic (1.25e-1)" "unprognostic (1.94e-1)" "unprognostic (2.31e-2)" "unprognostic (9.90e-2)" "unprognostic (3.56e-3)" "unprognostic (1.29e-1)" "unprognostic (3.34e-3)" "unprognostic (1.37e-1)" "unprognostic (4.03e-1)" "unprognostic (1.97e-1)" "unprognostic (5.10e-2)" "unprognostic (3.41e-1)" "unprognostic (6.46e-2)" "potential prognostic unfavorable (1.35e-4)" "unprognostic (1.05e-2)" "potential prognostic favorable (1.56e-4)" "unprognostic (3.06e-2)" "unprognostic (2.79e-3)" "unprognostic (5.01e-2)" "unprognostic (1.60e-1)" "unprognostic (9.71e-3)" "unprognostic (2.15e-1)" CREG1 CREG ENSG00000143162 "Cellular repressor of E1A stimulated genes 1" O75629 1 167529117-167553805 "Predicted secreted proteins" "Growth regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 306.0;Hofbauer cells: 1020.2;Kupffer cells: 1210.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 55.9;classical monocyte: 128.5;eosinophil: 75.9;intermediate monocyte: 75.6;myeloid DC: 89.9;neutrophil: 43.8;non-classical monocyte: 72.7" "Group enriched" "Detected in all" 6 "dendritic cells: 89.9;granulocytes: 75.9;monocytes: 128.5" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Lung - Macrophages, Spleen - Macrophages, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056390 Approved "Golgi apparatus,Vesicles,Microtubules" "Secreted to blood" Other NA NA 680000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 76: Non-specific - Metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 7: Liver cancer - Metabolism" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 4 "Golgi apparatus, Vesicles" Microtubules "HPA056390: " "unprognostic (2.06e-1)" "unprognostic (1.15e-1)" "unprognostic (1.93e-1)" "unprognostic (1.79e-1)" "unprognostic (3.20e-1)" "unprognostic (1.48e-2)" "unprognostic (2.55e-2)" "potential prognostic unfavorable (3.95e-4)" "unprognostic (1.19e-2)" "unprognostic (2.87e-2)" "potential prognostic favorable (2.33e-5)" "unprognostic (1.01e-1)" "unprognostic (2.56e-3)" "unprognostic (7.63e-2)" "unprognostic (2.05e-3)" "unprognostic (2.15e-1)" "unprognostic (2.91e-1)" "unprognostic (1.26e-1)" "unprognostic (2.51e-2)" "unprognostic (2.41e-1)" "potential prognostic unfavorable (4.88e-4)" "unprognostic (8.87e-2)" "unprognostic (1.82e-2)" "unprognostic (5.14e-2)" "unprognostic (6.25e-2)" "unprognostic (4.32e-2)" "unprognostic (1.75e-2)" "unprognostic (1.52e-1)" "unprognostic (1.20e-1)" "unprognostic (5.51e-3)" "unprognostic (4.04e-1)" CREG2 ENSG00000175874 "Cellular repressor of E1A stimulated genes 2" Q8IUH2 2 101345550-101387503 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 59 "brain: 53.2" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 91.3;Brain inhibitory neurons: 46.3;Granulosa cells: 10.5;Late spermatids: 9.6;Ocular epithelial cells: 28.7;Oligodendrocytes: 23.3;Other brain neurons: 32.4;Urothelial cells: 12.0" "Cell type enhanced" "Detected in many" "hippocampal dentate gyrus: 244.4" "Cancer enhanced" "Detected in single" "Glioblastoma Multiforme (TCGA): 1.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Esophageal cancer: 2.3" "Colon - Colon enteroendocrine cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038224 Enhanced "Secreted in brain" "No annotated function" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 35: Neurons - Synaptic function & neurogenesis" "HPA038224: " "unprognostic (1.92e-2)" "unprognostic (3.20e-1)" "unprognostic (1.39e-2)" CRELD1 "AVSD2, CIRRIN" ENSG00000163703 "Cysteine rich with EGF like domains 1" Q96HD1 3 9933793-9945413 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Isomerase "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 42.5;Bergmann glia: 39.4;Brain excitatory neurons: 44.5;Brain inhibitory neurons: 45.3;Choroid plexus epithelial cells: 34.1;Ependymal cells: 24.4;Loop of henle epithelial cells: 20.3;Microglia: 21.8;Oligodendrocyte progenitor cells: 33.9;Oligodendrocytes: 30.1;Other brain neurons: 42.3;Papillary tip epithelial cells: 22.3;Podocytes: 19.6;Proximal tubule cells: 15.8;Renal collecting duct intercalated cells: 21.4;Renal collecting duct principal cells: 18.8;Renal connecting tubule cells: 17.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026964 Uncertain Approved Nucleoli,Cytosol "Intracellular and membrane" Enzyme NA NA 8700000 "Cluster 25: Non-specific - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 14: Neurons - Synaptic function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 98: Neurons - Neurotransmission & signaling" 2 Cytosol Nucleoli "HPA026964: " "unprognostic (6.83e-2)" "unprognostic (6.92e-3)" "unprognostic (1.88e-1)" "unprognostic (1.42e-2)" "unprognostic (2.02e-2)" "potential prognostic unfavorable (1.83e-4)" "potential prognostic unfavorable (5.26e-4)" "unprognostic (1.86e-1)" "unprognostic (2.96e-2)" "unprognostic (7.02e-2)" "unprognostic (2.68e-1)" "unprognostic (1.85e-1)" "potential prognostic favorable (1.26e-5)" "unprognostic (4.29e-1)" "unprognostic (1.21e-1)" "unprognostic (8.47e-2)" "unprognostic (4.47e-1)" "unprognostic (4.99e-3)" "unprognostic (2.57e-1)" "unprognostic (1.57e-1)" "unprognostic (5.17e-2)" "unprognostic (1.21e-2)" "unprognostic (3.50e-2)" "unprognostic (1.61e-2)" "unprognostic (2.31e-1)" "unprognostic (1.91e-1)" "potential prognostic favorable (1.60e-4)" "unprognostic (7.71e-2)" "unprognostic (5.35e-2)" "unprognostic (3.24e-2)" "unprognostic (1.18e-2)" CRELD2 MGC11256 ENSG00000184164 "Cysteine rich with EGF like domains 2" Q6UXH1 22 49918167-49927540 "Enzymes, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early primary spermatocytes: 152.5;Epididymal principal cells: 328.9;Extravillous trophoblasts: 153.9;Pancreatic acinar cells: 154.9;Plasma cells: 364.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000603, CAB025604" Approved "Intracellular and membrane" Enzyme NA NA 590000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 70: Non-specific - Protein processing" "Cluster 46: Brainstem - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 8: Non-specific - Secretory pathway" 4 "CAB025604: , HPA000603: " "unprognostic (5.63e-2)" "unprognostic (1.47e-1)" "unprognostic (1.01e-1)" "unprognostic (1.81e-1)" "unprognostic (1.14e-1)" "unprognostic (8.91e-3)" "unprognostic (4.89e-2)" "unprognostic (3.97e-1)" "unprognostic (3.39e-2)" "unprognostic (1.80e-1)" "validated prognostic unfavorable (8.60e-4)" "validated prognostic unfavorable (6.55e-4)" "unprognostic (3.27e-2)" "unprognostic (1.74e-3)" "unprognostic (4.21e-2)" "unprognostic (1.21e-1)" "unprognostic (1.05e-1)" "unprognostic (6.72e-2)" "unprognostic (6.79e-2)" "unprognostic (7.37e-2)" "unprognostic (7.19e-2)" "unprognostic (7.50e-2)" "unprognostic (2.80e-2)" "unprognostic (2.58e-1)" "unprognostic (1.93e-2)" "unprognostic (3.82e-1)" "unprognostic (3.50e-1)" "unprognostic (4.59e-2)" "unprognostic (8.54e-2)" "unprognostic (2.05e-2)" "unprognostic (3.78e-3)" CREM hCREM-2 ENSG00000095794 "CAMP responsive element modulator" Q03060 10 35126791-35212958 "Predicted intracellular proteins, Transcription factors" "Biological rhythms, Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 194.3" "Cell type enhanced" "Detected in many" "Early spermatids: 2296.4;Late primary spermatocytes: 1684.7;Late spermatids: 1024.5;Mast cells: 724.0;Neutrophils: 739.9;NK-cells: 691.5;pDCs: 804.0;T-cells: 873.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001818, CAB018352" Enhanced Supported Nucleoplasm,Vesicles NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 67: Testis - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 5 Nucleoplasm Vesicles "CAB018352: , HPA001818: " "unprognostic (3.69e-1)" "unprognostic (7.65e-3)" "unprognostic (2.89e-1)" "unprognostic (2.16e-2)" "unprognostic (2.22e-1)" "unprognostic (2.19e-1)" "unprognostic (1.93e-1)" "unprognostic (6.12e-2)" "unprognostic (9.06e-2)" "unprognostic (1.68e-1)" "unprognostic (4.64e-2)" "potential prognostic favorable (8.09e-4)" "unprognostic (1.66e-2)" "unprognostic (6.22e-2)" "unprognostic (1.04e-1)" "unprognostic (1.14e-2)" "unprognostic (5.09e-2)" "unprognostic (1.13e-1)" "unprognostic (7.66e-2)" "unprognostic (1.78e-2)" "unprognostic (2.42e-2)" "unprognostic (1.32e-1)" "unprognostic (1.23e-2)" "unprognostic (2.12e-1)" "unprognostic (5.33e-2)" "unprognostic (5.64e-2)" "unprognostic (2.62e-1)" "unprognostic (4.55e-3)" "unprognostic (1.84e-1)" "unprognostic (1.86e-3)" "unprognostic (3.99e-2)" CRH "CRF, CRH1" ENSG00000147571 "Corticotropin releasing hormone" P06850 8 66176376-66178464 "Plasma proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "brain: 52.7" "Group enriched" "Detected in some" 5 "Pancreatic islet cells: 148.3;Syncytiotrophoblasts: 249.8" "Group enriched" "Detected in many" 7 "CGE interneuron: 168.6;LAMP5-LHX6 and Chandelier: 52.1;thalamic excitatory: 81.9" "Cancer enriched" "Detected in some" 5 "Bladder Urothelial Carcinoma (TCGA): 63.7" "Region enriched" "Detected in many" 6 "medulla oblongata: 317.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 17 "Rhabdoid: 960.6" "Adrenal gland - Adrenal medulla cells, Pancreas - Alpha cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted to blood" Hormone NA NA 10000 13000 "Cluster 36: Brain & Liver - Signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." 21 "unprognostic (1.71e-1)" "unprognostic (2.54e-1)" "unprognostic (7.81e-2)" CRHBP "CRF-BP, CRFBP" ENSG00000145708 "Corticotropin releasing hormone binding protein" P24387 5 76953045-76981158 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 56.5;liver: 155.7" "Cell type enriched" "Detected in some" 9 "Hematopoietic stem cells: 2019.0" "Group enriched" "Detected in many" 4 "mammillary body: 52.1;MGE interneuron: 94.7;splatter: 90.0" "Group enriched" "Detected in some" 4 "Glioblastoma Multiforme (TCGA): 1.7;Kidney Renal Clear Cell Carcinoma (TCGA): 2.2;Liver Hepatocellular Carcinoma (TCGA): 2.7;Testicular Germ Cell Tumor (TCGA): 4.9;Thyroid Carcinoma (TCGA): 2.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Brain cancer: 12.3" "Kidney - Podocytes, Liver - Sinusoid Endothelial cells, Minor Salivary Gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA036234, HPA046120" Approved Supported "Secreted to blood" "No annotated function" NA NA 720000000 16000000 "Cluster 16: Liver & Kidney - Metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 2 "HPA036234: , HPA046120: " "unprognostic (5.78e-2)" "unprognostic (1.79e-1)" "unprognostic (1.82e-1)" "validated prognostic favorable (1.79e-10)" "validated prognostic favorable (1.56e-4)" "validated prognostic favorable (6.75e-4)" "validated prognostic favorable (4.80e-5)" "unprognostic (1.43e-1)" "unprognostic (1.25e-1)" CRHR1 "CRF-R, CRF1, CRHR" ENSG00000120088 "Corticotropin releasing hormone receptor 1" P34998 17 45784277-45835828 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "brain: 18.7;pituitary gland: 18.5" "Cell type enriched" "Detected in some" 4 "Brain excitatory neurons: 35.3" "Cell type enhanced" "Detected in many" "upper rhombic lip: 60.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pituitary gland - Corticotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025251 Enhanced NA NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 15: Non-specific - Transcription" "Cluster 1: Neuronal - Visual perception" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 6 "CAB025251: " "unprognostic (7.33e-2)" "unprognostic (2.49e-1)" "unprognostic (3.10e-2)" CRHR2 "CRF-RB, CRF2, HM-CRF" ENSG00000106113 "Corticotropin releasing hormone receptor 2" Q13324 7 30651942-30700129 "G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "choroid plexus: 20.9" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 71.8;Epicardial cells: 22.7;Pericytes: 12.7;Retinal amacrine cells: 35.9;Retinal horizontal cells: 26.0;Somatotrophs: 11.4;Thyrotrophs: 16.0" "Cell type enriched" "Detected in many" 4 "choroid plexus epithelial cell: 100.8" "Not detected" "Not detected" "Region enhanced" "Detected in all" "choroid plexus: 48.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "thyroid cancer: 5.5" "Pituitary gland - Thyrotropes" "Region enhanced" "Detected in many" "basal ganglia: 8.1" "Low region specificity" "Detected in many" HPA073345 Supported "Plasma membrane" "Secreted - unknown location" Receptor NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "Plasma membrane" "HPA073345: " CRIM1 S52 ENSG00000150938 "Cysteine rich transmembrane BMP regulator 1" Q9NZV1 2 36355778-36551135 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 153.9" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 1163.5;Epicardial cells: 786.9;Podocytes: 1935.2;Vascular smooth muscle cells: 679.7" "Cell type enhanced" "Detected in all" "endothelial cell: 1377.3;vascular associated smooth muscle cell: 1358.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 2.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Liver - Hepatic stellate cells, Skin - Endothelial cells, Spleen - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000556 Enhanced "Intracellular and membrane" "No annotated function" NA NA 54000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" "HPA000556: " "unprognostic (4.64e-2)" "unprognostic (8.66e-2)" "unprognostic (1.27e-1)" "unprognostic (2.10e-2)" "unprognostic (1.62e-2)" "unprognostic (5.80e-2)" "unprognostic (2.44e-1)" "unprognostic (5.07e-3)" "unprognostic (1.96e-2)" "unprognostic (7.76e-2)" "potential prognostic favorable (2.66e-9)" "unprognostic (7.57e-3)" "unprognostic (1.39e-1)" "unprognostic (3.36e-2)" "unprognostic (4.20e-1)" "unprognostic (3.11e-2)" "unprognostic (1.49e-1)" "unprognostic (4.45e-2)" "unprognostic (1.27e-1)" "unprognostic (3.22e-3)" "unprognostic (1.53e-2)" "unprognostic (3.21e-2)" "unprognostic (6.00e-2)" "unprognostic (2.45e-1)" "unprognostic (7.09e-2)" "unprognostic (1.73e-1)" "unprognostic (3.93e-1)" "unprognostic (7.43e-2)" "unprognostic (2.96e-1)" "unprognostic (2.04e-1)" "unprognostic (4.19e-3)" CRIP1 CRIP ENSG00000213145 "Cysteine rich protein 1" P50238 14 105486317-105488947 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 548.9" "Cell type enhanced" "Detected in many" "cDC: 686.2;Endometrial ciliated cells: 1717.4;Endometrial luminal cells: 641.2;Enterocytes: 4887.8;Epididymal efferent duct ciliated cells: 2456.1;Epididymal principal cells: 1639.6;Vascular smooth muscle cells: 1103.9" "Cell type enriched" "Detected in some" 4 "vascular associated smooth muscle cell: 252.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Kidney - Fibroblasts, Minor Salivary Gland - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042462 Enhanced Approved "Nuclear speckles,Plasma membrane,Centrosome,Cytosol" NA NA 65000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 46: Brainstem - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 1: Enterocytes - Absorption and Digestion" 1 "Nuclear speckles, Cytosol" "Plasma membrane, Centrosome" "HPA042462: " "unprognostic (3.91e-1)" "unprognostic (1.82e-2)" "unprognostic (2.29e-1)" "unprognostic (6.11e-3)" "unprognostic (5.86e-2)" "unprognostic (2.18e-2)" "unprognostic (3.62e-2)" "unprognostic (3.12e-2)" "unprognostic (2.31e-1)" "unprognostic (6.70e-3)" "unprognostic (4.87e-2)" "unprognostic (6.89e-3)" "unprognostic (1.94e-1)" "unprognostic (9.08e-2)" "unprognostic (6.81e-3)" "unprognostic (1.35e-1)" "unprognostic (9.10e-2)" "unprognostic (4.25e-2)" "unprognostic (9.06e-3)" "unprognostic (1.91e-1)" "unprognostic (6.24e-3)" "unprognostic (2.76e-2)" "unprognostic (7.35e-2)" "unprognostic (2.16e-1)" "unprognostic (1.31e-2)" "unprognostic (2.44e-1)" "unprognostic (2.42e-1)" "unprognostic (4.91e-2)" "unprognostic (6.20e-2)" "unprognostic (1.40e-1)" CRIP2 "CRP2, ESP1" ENSG00000182809 "Cysteine rich protein 2" P52943 14 105472962-105480162 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 641.8;heart muscle: 1152.2" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 267.3;Esophageal apical cells: 803.2;Fallopian secretory cells: 247.2;Fallopian tube ciliated cells: 227.5;Lymphatic endothelial cells: 336.7;Vascular endothelial cells: 365.4;Vascular smooth muscle cells: 379.1" "Cell type enhanced" "Detected in many" "endothelial cell: 182.5;vascular associated smooth muscle cell: 155.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "memory B-cell: 52.3;memory CD4 T-cell: 80.5;naive B-cell: 111.0;T-reg: 116.0" "Group enriched" "Detected in all" 30 "B-cells: 111.0;T-cells: 116.0" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Heart muscle - Cardiomyocytes, Pancreas - Endothelial cells, Prostate - Endothelial cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042664 Approved Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA 520000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 35: Non-specific - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 4 Nucleoli "Nucleoplasm, Plasma membrane" "HPA042664: " "unprognostic (3.46e-1)" "unprognostic (1.81e-1)" "unprognostic (2.29e-1)" "unprognostic (6.46e-2)" "unprognostic (2.55e-3)" "unprognostic (8.95e-2)" "unprognostic (5.10e-1)" "unprognostic (1.84e-1)" "unprognostic (2.22e-1)" "unprognostic (3.48e-1)" "potential prognostic favorable (3.02e-5)" "unprognostic (7.56e-3)" "unprognostic (4.23e-3)" "unprognostic (4.48e-2)" "potential prognostic favorable (4.52e-5)" "unprognostic (6.96e-2)" "unprognostic (2.66e-1)" "unprognostic (9.55e-3)" "unprognostic (5.23e-2)" "unprognostic (2.76e-1)" "unprognostic (1.51e-1)" "unprognostic (5.67e-2)" "unprognostic (1.71e-1)" "unprognostic (3.54e-1)" "unprognostic (3.04e-2)" "unprognostic (3.60e-2)" "unprognostic (9.46e-2)" "unprognostic (3.35e-2)" "unprognostic (4.49e-2)" "unprognostic (1.04e-2)" "unprognostic (2.80e-1)" CRIP3 "bA480N24.2, TLP, TLP-A" ENSG00000146215 "Cysteine rich protein 3" Q6Q6R5 6 43299710-43308826 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 15.2;heart muscle: 22.8;testis: 24.6" "Cell type enhanced" "Detected in some" "Astrocytes: 7.2;Bergmann glia: 5.9;Brain inhibitory neurons: 4.3;Cardiomyocytes: 8.1;cDC: 4.3;Cholangiocytes: 5.9;Early primary spermatocytes: 4.7;Ependymal cells: 4.0;Epididymal efferent duct absorptive cells: 4.8;Late primary spermatocytes: 7.2;Late spermatids: 14.3;Oligodendrocyte progenitor cells: 7.2" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 11.5;Liver Hepatocellular Carcinoma (TCGA): 13.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 16 "myeloid DC: 44.7" "Lineage enriched" "Detected in many" 16 "dendritic cells: 44.7" "Cancer enhanced" "Detected in some" "lymphoma: 3.7" "Heart muscle - Cardiomyocytes, Spleen - B-cells (Spleen), Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA036198 Uncertain Approved "Nuclear speckles" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 35: Non-specific - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" "Nuclear speckles" "HPA036198: " "unprognostic (2.62e-2)" "unprognostic (3.99e-1)" "unprognostic (2.84e-1)" "unprognostic (3.52e-3)" "unprognostic (9.76e-2)" "unprognostic (4.21e-3)" "unprognostic (1.58e-3)" "potential prognostic favorable (1.97e-4)" "unprognostic (3.14e-2)" "unprognostic (1.91e-2)" "unprognostic (7.44e-3)" "unprognostic (1.07e-1)" "unprognostic (1.45e-1)" "unprognostic (1.44e-3)" "unprognostic (1.56e-2)" "unprognostic (5.84e-2)" "unprognostic (4.10e-2)" "unprognostic (7.36e-2)" CRIPT HSPC139 ENSG00000119878 "CXXC repeat containing interactor of PDZ3 domain" Q9P021 2 46616416-46630176 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Disease variant, Dwarfism, Ectodermal dysplasia, Hypotrichosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 218.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" HPA046080 Approved Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 9: Non-specific - Receptor signaling" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 97: Non-specific - Cellular respiration" 6 "Nucleoli fibrillar center" Nucleoplasm "HPA046080: " "unprognostic (3.94e-2)" "unprognostic (1.83e-2)" "unprognostic (4.57e-1)" "unprognostic (2.67e-1)" "unprognostic (1.31e-2)" "unprognostic (2.81e-1)" "unprognostic (2.03e-1)" "unprognostic (1.84e-1)" "unprognostic (1.63e-1)" "unprognostic (1.41e-2)" "potential prognostic favorable (2.04e-4)" "unprognostic (2.28e-2)" "unprognostic (1.87e-1)" "validated prognostic unfavorable (1.47e-5)" "validated prognostic unfavorable (4.83e-5)" "unprognostic (1.27e-1)" "unprognostic (9.20e-2)" "unprognostic (3.90e-3)" "unprognostic (3.12e-2)" "unprognostic (3.69e-1)" "unprognostic (1.80e-2)" "unprognostic (1.11e-1)" "unprognostic (1.44e-2)" "unprognostic (1.86e-2)" "unprognostic (7.39e-2)" "unprognostic (2.61e-2)" "unprognostic (2.00e-1)" "unprognostic (2.30e-1)" "unprognostic (3.57e-1)" "unprognostic (1.56e-1)" "unprognostic (3.25e-1)" CRISP1 "AEGL1, ARP, CRISP-1, HSCRISP1D, HSCRISP1G, HUMARP" ENSG00000124812 "Cysteine rich secretory protein 1" P54107 6 49834257-49877096 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "epididymis: 1486.0" "Cell type enriched" "Detected in some" 6 "Epididymal principal cells: 940.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA028445, HPA030534" Enhanced "Secreted in male reproductive system" "No annotated function" NA NA 16000 "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 34: Testis cancer - Unknown function" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" "HPA028445: , HPA030534: " CRISP2 "CRISP-2, CT36, GAPDL5, TPX1" ENSG00000124490 "Cysteine rich secretory protein 2" P16562 6 49692358-49713590 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 21 "testis: 482.3" "Cell type enriched" "Detected in some" 6 "Late spermatids: 40585.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Pancreatic Adenocarcinoma (TCGA): 2.1" "Region enhanced" "Detected in single" "choroid plexus: 1.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Intercalated cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Ductal cells, Pituitary gland - Corticotropes, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA031248 Enhanced "Secreted in male reproductive system" "No annotated function" NA NA 1700000 "Cluster 57: Testis - Spermatogenesis" "Cluster 44: Non-specific - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 19 "HPA031248: " "unprognostic (1.60e-2)" "unprognostic (3.22e-2)" "unprognostic (8.05e-2)" "unprognostic (3.61e-1)" CRISP3 "Aeg2, CRISP-3, CRS3, dJ442L6.3, SGP28" ENSG00000096006 "Cysteine rich secretory protein 3" P54108 6 49727376-49744437 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "fallopian tube: 1133.0;salivary gland: 2263.8" "Cell type enhanced" "Detected in some" "Endometrial luminal cells: 1305.2;Esophageal apical cells: 4516.2;Fallopian secretory cells: 2071.6;Neutrophil progenitors: 614.4;Salivary acinar cells: 1216.0" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Breast Invasive Carcinoma (TCGA): 45.6;Pancreatic Adenocarcinoma (TCGA): 93.5;Prostate Adenocarcinoma (TCGA): 128.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "neutrophil: 2.6;non-classical monocyte: 1.2" "Group enriched" "Detected in many" 19 "granulocytes: 2.6;monocytes: 1.2" "Cancer enhanced" "Detected in many" "breast cancer: 108.0;prostate cancer: 44.2" "Lung - Neutrophils_1, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Ductal cells, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA054392 Supported "Secreted in other tissues" "No annotated function" NA NA 510000000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 82: Salivary gland - Secretion" "Cluster 27: Breast cancer - Unknown function" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 1 "HPA054392: " "unprognostic (1.16e-1)" "unprognostic (8.29e-3)" "unprognostic (3.13e-1)" "unprognostic (1.15e-1)" "unprognostic (5.88e-2)" "unprognostic (7.73e-2)" "unprognostic (1.69e-2)" "unprognostic (3.21e-3)" "unprognostic (8.49e-2)" "unprognostic (1.19e-1)" "unprognostic (1.12e-1)" "unprognostic (1.28e-1)" "unprognostic (2.29e-2)" "unprognostic (1.56e-1)" "unprognostic (2.27e-1)" CRISPLD1 "Cocoacrisp, DKFZp762F133, LCRISP1" ENSG00000121005 "Cysteine rich secretory protein LCCL domain containing 1" Q9H336 8 74984505-75034558 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 66.0" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 116.2;Endometrial ciliated cells: 351.9;Ependymal cells: 227.3;Epididymal efferent duct ciliated cells: 146.9;Fallopian tube ciliated cells: 77.1;Oligodendrocyte progenitor cells: 82.6;Prostatic glandular cells: 353.1" "Cell type enhanced" "Detected in many" "ependymal cell: 217.3;oligodendrocyte precursor cell: 103.9" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 73.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 64.3" "Colon - Enteric glia cells, Skeletal muscle - Fibroblasts, Skin - Eccrine sweat gland cells, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA024725 Uncertain "Secreted - unknown location" "No annotated function" NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" "HPA024725: " "unprognostic (3.03e-1)" "unprognostic (4.14e-1)" "unprognostic (4.24e-2)" "unprognostic (3.38e-2)" "unprognostic (2.78e-2)" "unprognostic (1.27e-2)" "unprognostic (1.56e-1)" "unprognostic (5.90e-2)" "unprognostic (2.52e-1)" "unprognostic (4.55e-2)" "unprognostic (3.01e-3)" "unprognostic (1.55e-3)" "unprognostic (1.54e-2)" "unprognostic (1.64e-2)" "potential prognostic favorable (5.99e-4)" "unprognostic (6.95e-2)" "unprognostic (1.58e-1)" "unprognostic (1.20e-1)" "unprognostic (1.55e-2)" "unprognostic (2.66e-1)" "unprognostic (1.03e-2)" "unprognostic (2.12e-1)" "unprognostic (1.01e-1)" "unprognostic (2.13e-1)" "unprognostic (4.50e-2)" "unprognostic (1.20e-2)" "unprognostic (1.50e-1)" "unprognostic (1.60e-2)" "unprognostic (2.23e-1)" CRISPLD2 "DKFZP434B044, LCRISP2, LGL1" ENSG00000103196 "Cysteine rich secretory protein LCCL domain containing 2" Q9H0B8 16 84819985-84920768 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 673.0;Fibroblasts: 765.1;Hepatic stellate cells: 722.9;Leydig cells: 542.3;Neutrophils: 546.0;Pericytes: 1352.3;Peritubular myoid cells: 425.3;Prostatic glandular cells: 439.7;Smooth muscle cells: 856.6;Vascular smooth muscle cells: 1418.0" "Group enriched" "Detected in many" 4 "oligodendrocyte precursor cell: 145.9;vascular associated smooth muscle cell: 467.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "neutrophil: 87.5" "Lineage enriched" "Detected in many" 4 "granulocytes: 87.5" "Cancer enhanced" "Detected in many" "Kidney cancer: 28.9" "Colon - Neutrophils, Skin - Macrophages, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 20.4" "HPA030055, HPA075372" Approved Approved Vesicles "Secreted to blood" "No annotated function" NA No 219000000000 1400000 "Cluster 21: Neutrophils - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 103: Non-specific - Basic cellular processes" Vesicles "HPA030055: , HPA075372: " "unprognostic (5.34e-2)" "unprognostic (3.88e-2)" "unprognostic (1.26e-1)" "unprognostic (1.13e-1)" "unprognostic (1.11e-1)" "unprognostic (4.22e-2)" "unprognostic (6.15e-2)" "unprognostic (3.34e-3)" "unprognostic (2.91e-1)" "unprognostic (4.76e-2)" "unprognostic (1.37e-1)" "unprognostic (2.26e-2)" "unprognostic (2.76e-2)" "unprognostic (3.27e-2)" "unprognostic (1.41e-3)" "unprognostic (3.41e-2)" "unprognostic (6.19e-2)" "unprognostic (2.01e-3)" "unprognostic (7.05e-3)" "unprognostic (1.28e-2)" "unprognostic (5.60e-3)" "unprognostic (1.05e-1)" "unprognostic (7.12e-2)" "unprognostic (4.24e-2)" "unprognostic (9.58e-2)" "unprognostic (3.88e-3)" "unprognostic (7.41e-2)" "unprognostic (5.35e-3)" "unprognostic (4.17e-2)" "unprognostic (5.17e-3)" "unprognostic (2.68e-1)" CRK ENSG00000167193 "CRK proto-oncogene, adaptor protein" P46108 17 1420689-1463162 "Predicted intracellular proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 105.3;Distal convoluted tubule cells: 53.3;Loop of henle epithelial cells: 61.3;Microglia: 70.8;Papillary tip epithelial cells: 66.6;Podocytes: 50.3;Proximal tubule cells: 69.2;Renal collecting duct intercalated cells: 66.5;Renal collecting duct principal cells: 48.8;Renal connecting tubule cells: 61.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010485, HPA068087" Approved Approved "Nucleoplasm,Plasma membrane,Actin filaments,Basal body" NA NA 130000 "Cluster 21: Neutrophils - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 45: Non-specific - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 102: Non-specific - Mixed function" 158 "Plasma membrane" "Nucleoplasm, Actin filaments, Basal body" "CAB010485: , HPA068087: " "unprognostic (4.54e-2)" "unprognostic (1.91e-3)" "unprognostic (1.25e-1)" "unprognostic (3.35e-3)" "unprognostic (2.52e-2)" "unprognostic (1.85e-1)" "unprognostic (8.72e-2)" "unprognostic (3.19e-1)" "unprognostic (7.31e-2)" "unprognostic (1.42e-1)" "validated prognostic favorable (1.77e-7)" "validated prognostic favorable (1.16e-4)" "unprognostic (2.99e-1)" "unprognostic (2.03e-1)" "unprognostic (1.25e-2)" "unprognostic (4.70e-3)" "unprognostic (2.82e-1)" "unprognostic (1.04e-1)" "unprognostic (1.87e-1)" "unprognostic (3.52e-1)" "unprognostic (1.97e-3)" "unprognostic (5.62e-2)" "unprognostic (5.35e-2)" "unprognostic (6.08e-3)" "unprognostic (1.30e-1)" "unprognostic (2.02e-1)" "unprognostic (5.26e-3)" "unprognostic (9.13e-2)" "unprognostic (1.77e-1)" "unprognostic (9.07e-2)" "unprognostic (2.78e-1)" CRKL ENSG00000099942 "CRK like proto-oncogene, adaptor protein" P46109 22 20917407-20953747 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000532, HPA001100" Uncertain Enhanced Nucleoplasm,Cytosol NA NA 2100000 "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 47: Platelets - Hemostasis" 89 Nucleoplasm Cytosol "HPA000532: , HPA001100: " "unprognostic (2.90e-1)" "unprognostic (2.23e-1)" "unprognostic (1.29e-1)" "unprognostic (3.92e-2)" "unprognostic (3.29e-1)" "unprognostic (9.39e-2)" "unprognostic (4.22e-2)" "unprognostic (1.53e-1)" "unprognostic (2.05e-1)" "unprognostic (6.36e-3)" "potential prognostic favorable (3.12e-4)" "unprognostic (1.68e-2)" "unprognostic (7.29e-2)" "unprognostic (6.14e-3)" "unprognostic (5.28e-3)" "unprognostic (3.69e-2)" "unprognostic (5.79e-2)" "unprognostic (1.22e-1)" "unprognostic (1.04e-3)" "unprognostic (1.68e-1)" "unprognostic (3.70e-2)" "unprognostic (1.28e-1)" "unprognostic (1.07e-2)" "unprognostic (1.51e-1)" "unprognostic (2.74e-3)" "unprognostic (2.00e-1)" "unprognostic (4.49e-2)" "unprognostic (1.52e-1)" "unprognostic (1.57e-1)" "unprognostic (1.25e-1)" "unprognostic (3.15e-1)" CRLF1 "CISS, CISS1, CLF, CLF-1" ENSG00000006016 "Cytokine receptor like factor 1" O75462 19 18572220-18607741 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 231.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 310.3;Ependymal cells: 82.2;Epicardial cells: 147.8;Fibroblasts: 137.6;Vascular smooth muscle cells: 124.8" "Cell type enhanced" "Detected in all" "ependymal cell: 112.9" "Group enriched" "Detected in many" 7 "Lung Adenocarcinoma (TCGA): 130.6;Thyroid Carcinoma (TCGA): 100.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 46.5;thyroid cancer: 46.5" "Skin - Hair cortex cells, Skin - Inner root sheath cells, Spleen - Smooth muscle cells" "Region enriched" "Detected in many" 7 "hippocampal formation: 21.1" "Group enriched" "Detected in some" 6 "cerebellum: 2.7;spinal cord: 9.9" "HPA041493, HPA041793" Approved "Secreted in other tissues" Receptor NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 53: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 40 "HPA041493: , HPA041793: " "unprognostic (3.69e-2)" "unprognostic (2.38e-1)" "unprognostic (1.13e-1)" "unprognostic (7.47e-2)" "potential prognostic unfavorable (8.37e-4)" "unprognostic (3.63e-1)" "unprognostic (6.51e-3)" "unprognostic (1.23e-2)" "unprognostic (2.84e-2)" "unprognostic (9.99e-2)" "unprognostic (5.81e-2)" "potential prognostic unfavorable (2.88e-4)" "unprognostic (2.89e-1)" "unprognostic (1.36e-1)" "unprognostic (3.49e-2)" "unprognostic (3.77e-1)" "unprognostic (2.65e-2)" "unprognostic (1.44e-1)" "unprognostic (1.89e-3)" "unprognostic (3.21e-1)" "unprognostic (4.93e-2)" "potential prognostic unfavorable (1.93e-5)" "unprognostic (5.99e-2)" "unprognostic (1.07e-1)" "unprognostic (6.98e-2)" "unprognostic (1.16e-3)" "unprognostic (3.38e-2)" "unprognostic (3.50e-2)" "unprognostic (3.16e-2)" CRLF2 "CRL2, TSLPR" ENSG00000205755 "Cytokine receptor like factor 2" Q9HC73 X 1187549-1212723 "Cancer-related genes, Human disease related genes, Predicted membrane proteins" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 1.7;gallbladder: 1.2;lymphoid tissue: 1.4" "Cell type enriched" "Detected in some" 5 "Mast cells: 235.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Thyroid Carcinoma (TCGA): 1.6" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 13 "plasmacytoid DC: 1.2" "Lineage enriched" "Detected in single" 13 "dendritic cells: 1.2" "Group enriched" "Detected in some" 4 "Adrenocortical cancer: 7.0;Leukemia: 7.4;lymphoma: 2.4;Myeloma: 5.2" "Adipose subcutaneous - Mast cells, Adipose visceral - Mast cells, Colon - Mast cells, Lung - Mast cells" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA075272 Approved "Plasma membrane" "Intracellular and membrane" Receptor NA NA "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 6: Leukemia - Signal transduction" "Cluster 58: Mast cells - Allergic inflammatory responses" "Plasma membrane" "HPA075272: " "unprognostic (1.00e-1)" "unprognostic (2.50e-2)" CRLF3 "CREME9, CYTOR4" ENSG00000176390 "Cytokine receptor like factor 3" Q8IUI8 17 30769388-30824692 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 33.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 274.4;Neutrophil progenitors: 248.9;Neutrophils: 349.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007596 Enhanced Approved "Plasma membrane,Cytosol" NA NA 620000 "Cluster 21: Neutrophils - Unknown function" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 15: Non-specific - Transcription" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 29 "Plasma membrane, Cytosol" "HPA007596: " "unprognostic (7.07e-2)" "unprognostic (7.31e-2)" "unprognostic (1.53e-1)" "unprognostic (1.44e-2)" "unprognostic (2.01e-1)" "unprognostic (3.88e-2)" "unprognostic (8.10e-2)" "unprognostic (6.76e-2)" "unprognostic (1.89e-1)" "unprognostic (3.08e-1)" "unprognostic (2.07e-1)" "unprognostic (2.41e-1)" "unprognostic (4.88e-2)" "unprognostic (5.52e-3)" "unprognostic (5.26e-2)" "unprognostic (8.43e-2)" "unprognostic (5.85e-2)" "unprognostic (1.48e-1)" "unprognostic (4.54e-2)" "unprognostic (6.73e-2)" "unprognostic (1.99e-1)" "unprognostic (1.17e-1)" "unprognostic (1.17e-2)" "unprognostic (1.60e-1)" "unprognostic (1.45e-2)" "unprognostic (1.54e-2)" "unprognostic (1.08e-1)" "unprognostic (1.39e-1)" "unprognostic (1.41e-1)" "unprognostic (7.14e-2)" "unprognostic (4.39e-1)" CRLS1 "C20orf155, CLS1, dJ967N21.6, GCD10" ENSG00000088766 "Cardiolipin synthase 1" Q9UJA2 20 6006093-6040053 "Enzymes, Essential proteins, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Transferase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 158.4" "Cell type enhanced" "Detected in many" "Astrocytes: 41.0;Bergmann glia: 36.9;Brain excitatory neurons: 44.2;Brain inhibitory neurons: 40.3;Choroid plexus epithelial cells: 77.4;Distal convoluted tubule cells: 51.3;Ependymal cells: 51.8;Late spermatids: 40.9;Loop of henle epithelial cells: 64.2;Microglia: 47.1;Oligodendrocyte progenitor cells: 47.1;Oligodendrocytes: 41.1;Other brain neurons: 36.1;Papillary tip epithelial cells: 39.2;Podocytes: 49.8;Proximal tubule cells: 87.1;Renal collecting duct intercalated cells: 44.7;Renal collecting duct principal cells: 47.0;Renal connecting tubule cells: 46.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Mesothelial cells, Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 76: Non-specific - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 102: Non-specific - Mixed function" 2 "unprognostic (2.24e-1)" "unprognostic (2.40e-3)" "unprognostic (3.47e-2)" "unprognostic (1.22e-1)" "unprognostic (7.32e-2)" "unprognostic (2.36e-1)" "unprognostic (4.52e-2)" "unprognostic (2.87e-2)" "potential prognostic unfavorable (7.68e-4)" "unprognostic (5.91e-2)" "potential prognostic favorable (5.75e-4)" "unprognostic (1.88e-1)" "unprognostic (1.64e-1)" "unprognostic (4.88e-2)" "unprognostic (3.11e-1)" "unprognostic (3.06e-2)" "unprognostic (3.55e-1)" "unprognostic (4.41e-2)" "unprognostic (3.15e-3)" "unprognostic (6.03e-2)" "unprognostic (2.47e-1)" "unprognostic (2.01e-3)" "unprognostic (1.75e-2)" "unprognostic (5.03e-2)" "unprognostic (9.20e-2)" "unprognostic (3.70e-1)" "unprognostic (2.40e-1)" "unprognostic (1.03e-1)" "unprognostic (9.98e-2)" "unprognostic (3.00e-1)" "unprognostic (3.35e-1)" CRMP1 "DPYSL1, DRP-1" ENSG00000072832 "Collapsin response mediator protein 1" Q14194 4 5748084-5893086 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 82.7;pituitary gland: 63.6;retina: 52.8" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 83.2;Corticotrophs: 105.7;Epicardial cells: 120.5;Gonadotrophs: 107.9;Lactotrophs: 124.2;Loop of henle epithelial cells: 84.2;Müller glia: 127.0;Other brain neurons: 94.8;Retinal amacrine cells: 141.2;Retinal bipolar cells: 216.7;Retinal ganglion cells: 119.7;Retinal horizontal cells: 268.5;Thyrotrophs: 99.1" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Glioblastoma Multiforme (TCGA): 121.5;Testicular Germ Cell Tumor (TCGA): 35.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "Neuroblastoma: 197.8" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Adrenal medulla cells, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035640, CAB037313" Approved Supported Centrosome,Cytosol NA NA 630000 "Cluster 27: Cerebellum - Synaptic function" "Cluster 14: Neurons - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 23 Centrosome Cytosol "CAB037313: , HPA035640: " "potential prognostic unfavorable (4.70e-4)" "unprognostic (1.27e-1)" "unprognostic (3.24e-1)" "unprognostic (6.64e-2)" "unprognostic (1.13e-1)" "potential prognostic unfavorable (1.81e-4)" "unprognostic (2.71e-1)" "unprognostic (1.06e-3)" "unprognostic (4.11e-2)" "unprognostic (1.58e-2)" "validated prognostic favorable (2.07e-5)" "validated prognostic favorable (1.18e-4)" "unprognostic (2.52e-2)" "unprognostic (1.47e-2)" "unprognostic (4.71e-2)" "unprognostic (2.91e-1)" "unprognostic (5.83e-2)" "unprognostic (2.44e-1)" "unprognostic (2.89e-2)" "unprognostic (2.17e-1)" "unprognostic (7.80e-2)" "unprognostic (2.18e-3)" "unprognostic (4.24e-1)" "unprognostic (3.65e-1)" "unprognostic (1.57e-1)" "unprognostic (1.83e-2)" "unprognostic (7.76e-2)" "unprognostic (1.60e-2)" "unprognostic (1.13e-1)" "unprognostic (1.01e-1)" "unprognostic (2.15e-1)" CRNKL1 "CLF, Clf1, CRN, SYF3" ENSG00000101343 "Crooked neck pre-mRNA splicing factor 1" Q9BZJ0 20 20034368-20056046 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 103.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 17: Non-specific - RNA processing" 69 "unprognostic (1.66e-1)" "unprognostic (1.39e-2)" "unprognostic (2.19e-1)" "potential prognostic unfavorable (1.26e-4)" "unprognostic (1.41e-1)" "unprognostic (5.53e-2)" "unprognostic (3.50e-1)" "unprognostic (2.41e-2)" "unprognostic (1.54e-1)" "unprognostic (3.46e-2)" "potential prognostic favorable (1.67e-6)" "unprognostic (8.84e-3)" "unprognostic (7.52e-2)" "potential prognostic unfavorable (5.03e-5)" "unprognostic (2.95e-3)" "unprognostic (2.13e-1)" "unprognostic (1.99e-1)" "unprognostic (2.15e-2)" "unprognostic (2.28e-1)" "unprognostic (6.58e-3)" "unprognostic (9.77e-3)" "unprognostic (1.72e-2)" "unprognostic (4.56e-2)" "unprognostic (8.34e-2)" "unprognostic (2.99e-2)" "unprognostic (6.05e-3)" "unprognostic (1.00e-1)" "unprognostic (2.13e-1)" "unprognostic (3.32e-1)" "unprognostic (3.30e-2)" "unprognostic (3.28e-2)" CRNN "C1orf10, SEP53" ENSG00000143536 Cornulin Q9UBG3 1 152409243-152414263 "Disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 1338.6;esophagus: 5227.7;vagina: 1617.4" "Cell type enriched" "Detected in some" 18 "Esophageal apical cells: 52543.0" "Not detected" "Not detected" "Group enriched" "Detected in many" 9 "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 33.1;Head and Neck Squamous Cell Carcinoma (TCGA): 99.9;Stomach Adenocarcinoma (TCGA): 27.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 32 "cervical cancer: 21.9" "Skin - Inner root sheath cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA024343, CAB026182" Enhanced NA NA 790000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 14 "CAB026182: , HPA024343: " "unprognostic (6.83e-1)" "unprognostic (1.04e-1)" "unprognostic (5.36e-2)" "unprognostic (2.53e-1)" "unprognostic (9.46e-2)" "unprognostic (1.96e-1)" "unprognostic (2.05e-1)" "unprognostic (2.01e-1)" CROCC "CROCC1, ROLT, rootletin" ENSG00000058453 "Ciliary rootlet coiled-coil, rootletin" Q5TZA2 1 16740273-16972964 "Predicted intracellular proteins" "Cell cycle, Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ependymal cells: 212.5;Respiratory ciliated cells: 240.2;Rod photoreceptor cells: 329.8" "Cell type enhanced" "Detected in all" "ependymal cell: 231.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021191, HPA021762" Enhanced Supported "Plasma membrane,Primary cilium transition zone,Centrosome,Basal body,Mid piece" NA NA "Cluster 64: Non-specific - Transcription" "Cluster 46: Brainstem - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 65: Non-specific - Cell growth & division" 5 "Centrosome, Basal body" "Plasma membrane, Primary cilium transition zone, Mid piece" "HPA021191: , HPA021762: " "unprognostic (7.59e-3)" "unprognostic (2.51e-2)" "unprognostic (1.62e-1)" "unprognostic (3.12e-2)" "unprognostic (1.47e-1)" "unprognostic (4.13e-2)" "unprognostic (2.93e-1)" "unprognostic (1.13e-3)" "unprognostic (8.26e-3)" "unprognostic (1.75e-2)" "unprognostic (2.88e-2)" "unprognostic (1.12e-1)" "unprognostic (9.95e-2)" "potential prognostic unfavorable (5.47e-4)" "unprognostic (8.54e-2)" "unprognostic (3.82e-3)" "unprognostic (2.85e-1)" "unprognostic (6.77e-2)" "unprognostic (1.17e-1)" "unprognostic (1.60e-1)" "unprognostic (1.92e-1)" "unprognostic (4.96e-3)" "unprognostic (8.04e-2)" "unprognostic (1.19e-1)" "unprognostic (3.37e-1)" "potential prognostic favorable (6.17e-6)" "unprognostic (1.16e-1)" "unprognostic (1.33e-1)" "unprognostic (2.06e-1)" "unprognostic (3.84e-1)" "unprognostic (5.59e-2)" CROCC2 ENSG00000226321 "Ciliary rootlet coiled-coil, rootletin family member 2" H7BZ55 2 240906330-240993311 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "choroid plexus: 3.0;fallopian tube: 5.1;lymphoid tissue: 2.1" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 74.7;Endometrial ciliated cells: 194.6;Ependymal cells: 283.6;Epididymal efferent duct ciliated cells: 116.7;Fallopian tube ciliated cells: 127.8;Lactotrophs: 62.7;Respiratory ciliated cells: 203.4;Thyrotrophs: 88.7" "Cell type enriched" "Detected in some" 4 "ependymal cell: 289.6" "Cancer enriched" "Detected in single" 5 "Uterine Corpus Endometrial Carcinoma (TCGA): 2.2" "Group enriched" "Detected in many" 5 "choroid plexus: 49.6;midbrain: 13.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA048678 Enhanced NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 34: Ciliated cells - Cilia assembly & function" "HPA048678: " "unprognostic (4.55e-2)" "unprognostic (4.84e-2)" CROT COT ENSG00000005469 "Carnitine O-octanoyltransferase" Q9UKG9 7 87345664-87399794 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Transport" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 148.5;Cytotrophoblasts: 222.8;Prostatic hillock cells: 181.5;Urothelial cells: 163.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019052, HPA019364, HPA019365" Enhanced Approved Vesicles NA NA "Cluster 1: T-cells - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 63: Cytotrophoblasts - Basic cellular functions" Vesicles "HPA019052: , HPA019364: , HPA019365: " "unprognostic (2.43e-2)" "unprognostic (2.02e-1)" "unprognostic (2.02e-1)" "unprognostic (9.46e-2)" "unprognostic (4.20e-2)" "unprognostic (2.16e-1)" "unprognostic (3.80e-1)" "unprognostic (8.93e-3)" "unprognostic (9.18e-2)" "unprognostic (3.41e-1)" "potential prognostic favorable (3.66e-7)" "unprognostic (1.19e-1)" "unprognostic (1.34e-1)" "unprognostic (1.73e-1)" "unprognostic (3.86e-1)" "unprognostic (6.37e-2)" "unprognostic (2.43e-1)" "unprognostic (1.30e-2)" "unprognostic (1.57e-2)" "unprognostic (1.92e-1)" "unprognostic (8.26e-2)" "unprognostic (2.61e-1)" "unprognostic (2.09e-1)" "unprognostic (1.58e-1)" "unprognostic (2.31e-1)" "unprognostic (3.26e-2)" "unprognostic (5.56e-2)" "unprognostic (3.03e-3)" "unprognostic (1.83e-1)" "unprognostic (1.90e-2)" "unprognostic (2.77e-1)" CRP PTX1 ENSG00000132693 "C-reactive protein" P02741 1 159712289-159714589 "Cancer-related genes, Candidate cardiovascular disease genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 81 "liver: 8524.7" "Cell type enriched" "Detected in some" 12 "Hepatocytes: 2370.8" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 11 "Liver Hepatocellular Carcinoma (TCGA): 1039.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Gastric cancer: 1.1" "Liver - Neutrophils" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB005036, HPA027367, HPA027396" Supported Approved "Nucleoplasm,Vesicles,Intermediate filaments" "Secreted to blood" "Acute phase" NA NA 2920000000 3400000000 "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 7 "Nucleoplasm, Vesicles" "Intermediate filaments" "CAB005036: , HPA027367: , HPA027396: " "unprognostic (4.41e-2)" "unprognostic (4.64e-1)" "unprognostic (1.57e-3)" "unprognostic (1.00e-1)" "unprognostic (2.01e-2)" "unprognostic (1.63e-1)" "unprognostic (1.30e-1)" "unprognostic (1.61e-2)" "unprognostic (1.16e-3)" "unprognostic (8.16e-3)" "unprognostic (6.04e-2)" CRPPA "hCG_1745121, ISPD, Nip" ENSG00000214960 "CDP-L-ribitol pyrophosphorylase A" A4D126 7 16087525-16502504 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Limb-girdle muscular dystrophy, Lissencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 8.6" "Cell type enriched" "Detected in many" 4 "Choroid plexus epithelial cells: 1329.7" "Cell type enriched" "Detected in all" 6 "choroid plexus epithelial cell: 1374.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 29 "basophil: 13.9" "Lineage enriched" "Detected in single" 29 "granulocytes: 13.9" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053554 Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 32: Basophils - Transcription" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 101: Choroid plexus epithelial cells - Ion transport" "Nucleoli fibrillar center" Nucleoplasm "HPA053554: " "unprognostic (8.52e-2)" "unprognostic (1.02e-2)" "unprognostic (1.28e-2)" "unprognostic (1.40e-1)" "unprognostic (6.48e-2)" "unprognostic (7.69e-2)" "unprognostic (1.71e-1)" "unprognostic (2.16e-1)" "validated prognostic favorable (1.47e-8)" "validated prognostic favorable (7.44e-6)" "unprognostic (3.13e-3)" "unprognostic (1.58e-1)" "unprognostic (3.25e-1)" "unprognostic (6.17e-2)" "unprognostic (2.07e-2)" "unprognostic (5.50e-2)" "unprognostic (2.38e-3)" "unprognostic (1.45e-1)" "unprognostic (2.05e-1)" "potential prognostic favorable (9.87e-4)" "unprognostic (4.48e-2)" "unprognostic (1.02e-2)" "unprognostic (1.33e-2)" "unprognostic (5.54e-2)" CRTAC1 "ASPIC1, CEP-68, FLJ10320" ENSG00000095713 "Cartilage acidic protein 1" Q9NQ79 10 97865000-98030828 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 61.8;lung: 47.1;urinary bladder: 50.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 166.1;Corticotrophs: 87.2;Epididymal basal cells: 172.0;Fallopian secretory cells: 106.2;Ocular epithelial cells: 508.8;Oligodendrocyte progenitor cells: 89.2;Retinal amacrine cells: 160.1;Retinal ganglion cells: 88.8;Transitional alveolar cells: 111.7;Urothelial cells: 205.1" "Cell type enhanced" "Detected in all" "LAMP5-LHX6 and Chandelier: 152.1" "Group enriched" "Detected in many" 8 "Kidney Chromophobe (TCGA): 329.5;Skin Cutaneous Melanoma (TCGA): 98.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney cancer: 6.0;skin cancer: 4.9" "Colon - Enteric glia cells, Liver - Vascular endothelial cells, Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008175 Enhanced "Secreted to extracellular matrix" "No annotated function" NA NA 570000000 "Cluster 74: Non-specific - Signal transduction" "Cluster 49: Hindbrain - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 100: Stratified epithelial cells - Barrier functions" 6 "HPA008175: " "unprognostic (2.75e-3)" "unprognostic (2.51e-1)" "unprognostic (1.83e-2)" "unprognostic (1.61e-1)" "unprognostic (9.13e-2)" "potential prognostic favorable (2.29e-4)" "unprognostic (6.46e-3)" "unprognostic (6.08e-2)" "unprognostic (4.78e-2)" "unprognostic (3.48e-2)" "unprognostic (2.12e-1)" "potential prognostic favorable (2.95e-4)" "unprognostic (4.13e-3)" "unprognostic (3.84e-3)" "unprognostic (3.03e-1)" "unprognostic (2.68e-1)" "unprognostic (7.13e-2)" "unprognostic (5.84e-2)" "unprognostic (4.29e-2)" "unprognostic (1.08e-1)" "unprognostic (4.60e-3)" "unprognostic (6.21e-3)" "unprognostic (5.70e-3)" "unprognostic (1.45e-2)" CRTAM CD355 ENSG00000109943 "Cytotoxic and regulatory T cell molecule" O95727 11 122838500-122872643 "CD markers, Predicted membrane proteins" "Adaptive immunity, Cell adhesion, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "brain: 128.2" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 53.3;Innate lymphoid cells: 21.4;NK-cells: 73.8;T-cells: 127.6;Thymocytes: 21.2" "Cell type enhanced" "Detected in some" "cerebellar inhibitory: 56.6;upper rhombic lip: 146.2" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 9 "cerebellum: 79.0" "Immune cell enhanced" "Detected in many" "NK-cell: 54.1" "Group enriched" "Detected in many" 4 "NK-cells: 54.1;T-cells: 33.3" "Not detected" "Not detected" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Colon - T-cells, Liver - T-cells, Prostate - T-cells, Spleen - T-cells" "Region enriched" "Detected in some" 44 "cerebellum: 102.6" "Region enhanced" "Detected in all" "cerebellum: 41.5" NA NA 19000 "Cluster 24: Non-specific - Transcription" "Cluster 71: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 59: Leukemia - T-cell receptor" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" "unprognostic (2.24e-2)" "unprognostic (3.11e-1)" "potential prognostic favorable (1.38e-4)" "unprognostic (3.05e-1)" "unprognostic (1.96e-2)" "unprognostic (1.43e-1)" "unprognostic (1.08e-2)" "unprognostic (1.47e-1)" "unprognostic (1.27e-1)" "unprognostic (2.32e-1)" "unprognostic (3.58e-2)" "unprognostic (1.53e-2)" "unprognostic (7.74e-2)" "unprognostic (7.38e-2)" CRTAP "CASP, LEPREL3, P3H5" ENSG00000170275 "Cartilage associated protein" O75718 3 33114014-33147773 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Disease variant, Dwarfism, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 194.5;Smooth muscle cells: 169.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 377.9" "Group enriched" "Detected in all" 5 "dendritic cells: 307.2;monocytes: 377.9" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043598, HPA044150" Approved Approved "Intermediate filaments,Actin filaments,Cytosol" "Secreted to blood" "No annotated function" NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 19: Astrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 24 "Intermediate filaments, Actin filaments, Cytosol" "HPA043598: , HPA044150: " "unprognostic (2.66e-2)" "unprognostic (1.65e-1)" "unprognostic (2.41e-2)" "unprognostic (4.82e-2)" "unprognostic (7.99e-2)" "unprognostic (1.50e-1)" "unprognostic (1.65e-2)" "unprognostic (1.21e-3)" "unprognostic (2.55e-3)" "unprognostic (7.63e-3)" "unprognostic (2.40e-3)" "unprognostic (3.85e-2)" "unprognostic (3.03e-2)" "unprognostic (1.09e-2)" "unprognostic (1.01e-3)" "unprognostic (2.61e-1)" "unprognostic (1.20e-2)" "unprognostic (3.39e-1)" "unprognostic (2.66e-1)" "unprognostic (3.76e-2)" "unprognostic (7.03e-3)" "unprognostic (3.09e-1)" "unprognostic (2.93e-3)" "unprognostic (7.08e-2)" "unprognostic (1.52e-1)" "unprognostic (7.80e-3)" "unprognostic (1.10e-2)" "unprognostic (7.07e-2)" "unprognostic (5.69e-2)" "unprognostic (5.74e-2)" "potential prognostic favorable (9.23e-4)" CRTC1 "FLJ14027, KIAA0616, MECT1, TORC1" ENSG00000105662 "CREB regulated transcription coactivator 1" Q6UUV9 19 18683678-18782333 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Biological rhythms, Host-virus interaction, Transcription, Transcription regulation" Activator "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 72.4" "Cell type enhanced" "Detected in many" "Retinal amacrine cells: 149.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022035, HPA063619" Enhanced Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 32: Basophils - Transcription" "Cluster 27: Cerebellum - Synaptic function" "Cluster 34: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 109: Neurons - Neuronal signaling" 23 "Nuclear bodies, Plasma membrane, Cytosol" Nucleoplasm "HPA022035: , HPA063619: " "unprognostic (2.92e-2)" "unprognostic (6.22e-3)" "unprognostic (1.15e-1)" "unprognostic (1.53e-1)" "unprognostic (5.58e-2)" "unprognostic (9.21e-2)" "unprognostic (1.41e-1)" "unprognostic (1.66e-2)" "unprognostic (6.57e-3)" "unprognostic (1.79e-1)" "unprognostic (6.46e-3)" "unprognostic (3.58e-3)" "unprognostic (4.91e-2)" "unprognostic (7.80e-3)" "unprognostic (7.71e-2)" "unprognostic (1.09e-1)" "unprognostic (6.15e-2)" "unprognostic (6.87e-3)" "unprognostic (7.44e-2)" "unprognostic (5.59e-2)" "unprognostic (2.23e-2)" "unprognostic (4.22e-3)" "unprognostic (6.81e-3)" "unprognostic (4.20e-2)" "unprognostic (1.26e-1)" "potential prognostic favorable (2.14e-4)" "unprognostic (1.20e-1)" "unprognostic (6.96e-3)" "unprognostic (4.37e-2)" "unprognostic (2.43e-2)" "unprognostic (1.63e-2)" CRTC2 TORC2 ENSG00000160741 "CREB regulated transcription coactivator 2" Q53ET0 1 153947669-153958615 "Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Megakaryocytes: 43.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pancreas - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028454, HPA028465" Supported Enhanced Nucleoplasm NA NA 6800 "Cluster 21: Neutrophils - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 45: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 28 Nucleoplasm "HPA028454: , HPA028465: " "unprognostic (1.13e-2)" "unprognostic (4.78e-2)" "unprognostic (9.94e-2)" "unprognostic (4.34e-2)" "unprognostic (2.25e-2)" "unprognostic (4.92e-2)" "unprognostic (4.93e-1)" "unprognostic (1.08e-1)" "unprognostic (6.82e-2)" "unprognostic (1.12e-1)" "unprognostic (8.78e-2)" "unprognostic (3.42e-1)" "unprognostic (7.94e-3)" "unprognostic (5.66e-3)" "unprognostic (2.55e-1)" "unprognostic (7.55e-2)" "unprognostic (2.95e-2)" "unprognostic (1.43e-1)" "unprognostic (3.95e-1)" "unprognostic (7.40e-2)" "unprognostic (1.31e-1)" "unprognostic (1.62e-1)" "unprognostic (4.37e-3)" "unprognostic (1.68e-1)" "unprognostic (1.46e-2)" "unprognostic (4.01e-1)" "unprognostic (3.00e-1)" "unprognostic (8.44e-2)" "unprognostic (4.82e-2)" "unprognostic (1.41e-1)" "unprognostic (1.64e-2)" CRTC3 FLJ21868 ENSG00000140577 "CREB regulated transcription coactivator 3" Q6UUV7 15 90529923-90645345 "Cancer-related genes, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" Activator "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 14.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Spleen - B-cells (Spleen), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043735, HPA063691" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 9: T-cells - Adaptive immunity: Regulation" 24 Nucleoplasm Cytosol "HPA043735: , HPA063691: " "unprognostic (1.04e-2)" "unprognostic (2.68e-1)" "unprognostic (2.50e-1)" "unprognostic (2.79e-1)" "unprognostic (1.42e-1)" "unprognostic (7.41e-2)" "unprognostic (8.16e-2)" "unprognostic (4.47e-1)" "unprognostic (6.71e-2)" "unprognostic (5.04e-2)" "validated prognostic favorable (2.43e-6)" "validated prognostic favorable (5.75e-4)" "unprognostic (3.44e-1)" "unprognostic (8.01e-3)" "unprognostic (2.00e-1)" "unprognostic (2.22e-1)" "unprognostic (1.18e-1)" "unprognostic (4.98e-2)" "unprognostic (2.00e-1)" "unprognostic (1.97e-2)" "unprognostic (2.58e-1)" "unprognostic (3.18e-1)" "unprognostic (1.40e-1)" "unprognostic (4.75e-1)" "unprognostic (1.87e-1)" "unprognostic (6.81e-2)" "unprognostic (4.57e-2)" "unprognostic (4.55e-2)" "unprognostic (8.08e-2)" "unprognostic (1.20e-1)" "unprognostic (1.59e-1)" CRX "CORD2, CRD, LCA7, OTX3" ENSG00000105392 "Cone-rod homeobox" O43186 19 47819779-47843330 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Sensory transduction, Transcription, Transcription regulation, Vision" "Activator, Developmental protein, DNA-binding" "Cone-rod dystrophy, Disease variant, Leber congenital amaurosis, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 122 "retina: 202.2" "Group enriched" "Detected in some" 4 "Cone photoreceptor cells: 358.1;Retinal pigment epithelial cells: 370.9;Rod photoreceptor cells: 556.0" "Group enriched" "Detected in some" 6 "choroid plexus epithelial cell: 3.6;upper rhombic lip: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 1.2;Uterine cancer: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA036762, HPA036763" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Primary cilium,Cytosol" NA NA "Cluster 42: Retina - Visual perception" "Cluster 48: Non-specific - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 79: Photoreceptor cells - Phototransduction" 96 "Nucleoli fibrillar center" "Nucleoplasm, Primary cilium, Cytosol" "HPA036762: , HPA036763: " "unprognostic (5.61e-2)" CRY1 PHLL1 ENSG00000008405 "Cryptochrome circadian regulator 1" Q16526 12 106991364-107093549 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Biological rhythms, Sensory transduction, Transcription, Transcription regulation" "Photoreceptor protein, Receptor, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB018762 Approved Supported "Nucleoplasm,Nuclear membrane,Microtubules" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 47: Testis - Mixed function" "Cluster 25: Non-specific - Transcription" "Cluster 72: Neuronal - Signal transduction" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 33 "Nucleoplasm, Nuclear membrane, Microtubules" "CAB018762: " "unprognostic (5.39e-2)" "unprognostic (2.72e-3)" "unprognostic (1.68e-1)" "unprognostic (7.43e-2)" "unprognostic (5.16e-2)" "unprognostic (6.06e-2)" "unprognostic (3.28e-1)" "unprognostic (4.64e-2)" "unprognostic (3.78e-1)" "unprognostic (4.01e-3)" "potential prognostic favorable (6.75e-5)" "unprognostic (9.07e-3)" "unprognostic (1.08e-1)" "unprognostic (2.70e-2)" "unprognostic (2.61e-1)" "unprognostic (4.28e-1)" "unprognostic (9.13e-2)" "unprognostic (1.95e-1)" "unprognostic (5.75e-3)" "unprognostic (2.41e-2)" "unprognostic (3.99e-2)" "unprognostic (2.35e-2)" "unprognostic (1.93e-1)" "unprognostic (4.18e-1)" "unprognostic (3.17e-1)" "unprognostic (5.47e-2)" "unprognostic (1.01e-2)" "unprognostic (6.55e-2)" "unprognostic (2.74e-1)" "unprognostic (2.30e-1)" "unprognostic (2.26e-1)" CRY2 ENSG00000121671 "Cryptochrome circadian regulator 2" Q49AN0 11 45847118-45883248 "Predicted intracellular proteins" "Biological rhythms, Sensory transduction, Transcription, Transcription regulation" "Photoreceptor protein, Receptor, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Retinal amacrine cells: 214.8;Retinal bipolar cells: 223.7;Retinal ganglion cells: 173.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 72.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037577 Supported Supported "Nuclear speckles,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 33: Neurons - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 47 "Nuclear speckles" Cytosol "HPA037577: " "unprognostic (2.96e-2)" "unprognostic (1.44e-1)" "unprognostic (5.86e-2)" "unprognostic (1.58e-1)" "unprognostic (6.95e-2)" "unprognostic (3.03e-1)" "unprognostic (2.55e-1)" "unprognostic (1.71e-2)" "unprognostic (8.51e-2)" "unprognostic (3.16e-1)" "validated prognostic favorable (2.30e-9)" "validated prognostic favorable (2.73e-8)" "potential prognostic favorable (1.03e-5)" "unprognostic (4.83e-3)" "potential prognostic favorable (2.17e-4)" "unprognostic (2.37e-3)" "unprognostic (2.54e-1)" "unprognostic (1.39e-1)" "unprognostic (4.06e-2)" "unprognostic (6.51e-2)" "unprognostic (3.36e-2)" "unprognostic (8.41e-3)" "unprognostic (1.69e-1)" "unprognostic (2.09e-1)" "unprognostic (3.70e-3)" "unprognostic (2.41e-1)" "unprognostic (3.07e-1)" "unprognostic (7.61e-3)" "unprognostic (1.77e-1)" "unprognostic (2.59e-2)" "unprognostic (5.64e-2)" CRYAA "CRYA1, HSPB4" ENSG00000160202 "Crystallin alpha A" P02489 21 43169008-43172805 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Sensory transduction, Vision" "Chaperone, Eye lens protein" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "kidney: 104.3;retina: 95.5" "Cell type enriched" "Detected in single" 12 "Müller glia: 1.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Liver Hepatocellular Carcinoma (TCGA): 5.6;Uterine Corpus Endometrial Carcinoma (TCGA): 1.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 8 "liver cancer: 3.5" "Region enhanced" "Detected in some" "hippocampal formation: 3.9" "Group enriched" "Detected in some" 16 "cerebral cortex: 51.6;hippocampal formation: 46.6" "HPA037737, HPA038430" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 34: Non-specific - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 11: Muller glia cells - Retinal homeostasis" 95 Cytosol Nucleoplasm "HPA037737: , HPA038430: " "unprognostic (6.78e-2)" "unprognostic (2.96e-1)" "unprognostic (1.40e-3)" "unprognostic (1.11e-3)" CRYAB "CRYA2, HSPB5" ENSG00000109846 "Crystallin alpha B" P02511 11 111908564-111923722 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Chaperone, Eye lens protein" "Cancer-related genes, Cardiomyopathy, Cataract, Disease variant, Myofibrillar myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 10537.6;skeletal muscle: 7429.7;tongue: 8772.8" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 1202.9;Endometrial glandular cells: 1087.8;Epididymal basal cells: 1094.8;Epididymal clear cells: 1281.9;Epididymal efferent duct absorptive cells: 3658.9;Epididymal efferent duct ciliated cells: 2186.2;Esophageal apical cells: 2670.2;Müller glia: 1134.1;Ocular epithelial cells: 1075.7;Pancreatic duct cells: 1898.2;Schwann cells: 3218.7;Thymic myoid cells: 3390.9" "Cell type enhanced" "Detected in all" "astrocyte: 484.0;oligodendrocyte: 1086.7" "Group enriched" "Detected in all" 6 "Glioblastoma Multiforme (TCGA): 3128.0;Kidney Renal Clear Cell Carcinoma (TCGA): 2118.3;Kidney Renal Papillary Cell Carcinoma (TCGA): 7571.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 236.2;ovarian cancer: 273.3" "Adipose subcutaneous - Adipocytes (Subcutaneous), Colon - Enteric glia cells, Prostate - Smooth muscle cells, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002053, CAB040560, HPA057100" Enhanced Enhanced "Plasma membrane,Cytosol" "Intracellular and membrane" Other NA NA 510000 "Cluster 41: Striated muscle - Muscle contraction" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 61: Schwann cells & Melanocytes - Mixed function" 74 "Plasma membrane, Cytosol" "CAB002053: , CAB040560: , HPA057100: " "unprognostic (9.83e-2)" "unprognostic (2.70e-2)" "unprognostic (3.07e-1)" "unprognostic (1.02e-1)" "potential prognostic unfavorable (6.57e-4)" "unprognostic (5.21e-2)" "unprognostic (3.00e-2)" "unprognostic (9.22e-3)" "unprognostic (1.66e-3)" "unprognostic (3.72e-3)" "unprognostic (1.01e-3)" "unprognostic (1.22e-1)" "unprognostic (6.98e-3)" "unprognostic (3.96e-3)" "unprognostic (3.30e-1)" "unprognostic (1.45e-1)" "unprognostic (9.35e-2)" "unprognostic (3.00e-1)" "unprognostic (1.44e-1)" "unprognostic (9.18e-3)" "unprognostic (5.91e-2)" "unprognostic (5.27e-2)" "unprognostic (3.81e-1)" "unprognostic (4.84e-2)" "potential prognostic unfavorable (9.71e-4)" "unprognostic (5.66e-2)" "unprognostic (2.25e-1)" "unprognostic (4.54e-2)" "unprognostic (1.61e-1)" "unprognostic (2.22e-1)" "unprognostic (1.15e-2)" CRYBA1 CRYB1 ENSG00000108255 "Crystallin beta A1" P05813 17 29246859-29254494 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Eye lens protein" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 3.4;Cardiomyocytes: 13.0;Endometrial luminal cells: 3.1;Epicardial cells: 9.1;Myonuclei: 3.8;Schwann cells: 6.3;Syncytiotrophoblasts: 6.3;Thymocytes: 5.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "hippocampal formation: 2.7;hypothalamus: 1.2;thalamus: 1.2" "Low region specificity" "Detected in all" HPA022016 Supported NA NA "Cluster 6: Non-specific - Immune response" "Cluster 34: Testis cancer - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 21 "HPA022016: " CRYBA2 ENSG00000163499 "Crystallin beta A2" P53672 2 218990189-218993422 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Eye lens protein" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "pancreas: 16.2;pituitary gland: 13.6" "Group enriched" "Detected in some" 26 "Neuroendocrine cells: 938.2;Pancreatic islet cells: 1063.7" "Cell type enriched" "Detected in single" 6 "lower rhombic lip: 5.5" "Cancer enriched" "Detected in some" 21 "Pancreatic Adenocarcinoma (TCGA): 50.8" "Group enriched" "Detected in many" 6 "midbrain: 23.4;pons: 10.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 4.7;Neuroblastoma: 4.3" "Adrenal gland - Adrenal medulla cells, Pancreas - Alpha cells, Prostate - Prostate glandular cells, Stomach - Gastric enteroendocrine cells, Testis - Early spermatids, Testis - Late spermatids" "Region enhanced" "Detected in some" "pons and medulla: 4.3" "Low region specificity" "Detected in many" HPA062293 Supported NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" 23 "HPA062293: " "unprognostic (3.46e-1)" "potential prognostic favorable (7.30e-4)" "unprognostic (7.19e-2)" "unprognostic (1.07e-2)" "unprognostic (3.90e-2)" CRYBA4 ENSG00000196431 "Crystallin beta A4" P53673 22 26621963-26630669 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Eye lens protein" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "epididymis: 1.4;testis: 1.1" "Cell type enhanced" "Detected in some" "Epididymal principal cells: 13.9;Late primary spermatocytes: 3.8;Neutrophils: 5.3;Parietal cells: 1.8;Plasma cells: 4.8;Schwann cells: 2.1;Undifferentiated spermatogonia: 5.5" "Cell type enhanced" "Detected in single" "upper rhombic lip: 1.9" "Group enriched" "Detected in some" 4 "Liver Hepatocellular Carcinoma (TCGA): 1.2;Testicular Germ Cell Tumor (TCGA): 1.3;Uterine Corpus Endometrial Carcinoma (TCGA): 2.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lymphoma: 1.1" "Minor Salivary Gland - Plasma cells, Skin - Inner root sheath cells" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "cerebral cortex: 4.7;hippocampal formation: 4.3" HPA071178 Supported NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 67: Plasma cells - Plasma cell differentiation" 12 "HPA071178: " "unprognostic (2.08e-2)" "unprognostic (6.78e-1)" "unprognostic (5.95e-2)" "unprognostic (1.24e-2)" CRYBB1 ENSG00000100122 "Crystallin beta B1" P53674 22 26599278-26618027 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Eye lens protein" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 9.1" "Cell type enriched" "Detected in some" 4 "Hofbauer cells: 168.0" "Cell type enriched" "Detected in some" 5 "central nervous system macrophage: 6.3" "Group enriched" "Detected in many" 6 "Glioblastoma Multiforme (TCGA): 4.5;Liver Hepatocellular Carcinoma (TCGA): 4.3;Testicular Germ Cell Tumor (TCGA): 4.7;Uterine Corpus Endometrial Carcinoma (TCGA): 14.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 6 "intermediate monocyte: 10.3;non-classical monocyte: 7.6" "Lineage enriched" "Detected in many" 7 "monocytes: 10.3" "Cancer enriched" "Detected in some" 6 "Myeloma: 12.6" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Minor Salivary Gland - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA003448, CAB010058" Supported NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 22: Epididymis - Mixed function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 6 "CAB010058: , HPA003448: " "unprognostic (8.38e-2)" "unprognostic (6.75e-2)" "unprognostic (1.51e-1)" "unprognostic (4.34e-2)" "unprognostic (2.41e-1)" "unprognostic (3.76e-2)" "unprognostic (2.07e-3)" "unprognostic (3.43e-3)" "unprognostic (3.97e-2)" "unprognostic (1.82e-2)" CRYBB2 "CCA2, CRYB2, CRYB2A" ENSG00000244752 "Crystallin beta B2" P43320 22 25212564-25231870 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Eye lens protein" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.2" "Cell type enhanced" "Detected in many" "Breast secretory cells: 4.5;Endometrial glandular cells: 5.5;Endometrial luminal cells: 5.4;Late spermatids: 12.9;Medullary thymic epithelial cells: 4.8;Neutrophils: 6.3" "Cell type enhanced" "Detected in many" "deep-layer corticothalamic and 6b: 11.0;hippocampal CA1-3: 11.7" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 2.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Neuroblastoma: 1.2" "Skin - Inner root sheath cells" "Region enhanced" "Detected in some" "hippocampal formation: 1.7" "Low region specificity" "Detected in many" HPA043749 Supported Approved Nucleoplasm NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 35: Neurons - Synaptic function & neurogenesis" 12 Nucleoplasm "HPA043749: " "unprognostic (7.33e-2)" "unprognostic (4.00e-1)" "unprognostic (6.58e-2)" CRYBB3 CRYB3 ENSG00000100053 "Crystallin beta B3" P26998 22 25199858-25207359 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Eye lens protein" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Colonocytes: 2.3;Endometrial glandular cells: 2.4;Müller glia: 6.0;Prostatic club cells: 2.6;Respiratory basal cells: 2.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA055840 Supported Approved "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 76: Non-specific - Metabolism" "Cluster 38: Sub-cortical - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 37 Microtubules "Cytokinetic bridge, Mitotic spindle" "HPA055840: " "unprognostic (5.16e-3)" "unprognostic (4.14e-2)" "unprognostic (1.42e-1)" "unprognostic (2.83e-1)" "unprognostic (4.55e-2)" "unprognostic (3.08e-1)" "unprognostic (1.80e-2)" "unprognostic (1.35e-3)" "unprognostic (1.17e-2)" "unprognostic (1.76e-1)" CRYBG1 "AIM1, ST4" ENSG00000112297 "Crystallin beta-gamma domain containing 1" 6 106360717-106572017 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 65.5;placenta: 67.6" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 806.2;Esophageal apical cells: 2189.7;Esophageal suprabasal cells: 575.3;Ocular epithelial cells: 641.8;Papillary tip epithelial cells: 565.0;Renal collecting duct principal cells: 545.8;Syncytiotrophoblasts: 1007.5;T-cells: 571.5;Urothelial cells: 722.1" "Group enriched" "Detected in all" 10 "choroid plexus epithelial cell: 592.1;leukocyte: 200.3" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 17 "choroid plexus: 84.9" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Prostate - Prostate glandular cells, Testis - Early spermatids" "Region enriched" "Detected in single" 5 "olfactory bulb: 4.2" "Low region specificity" "Detected in many" "CAB026378, HPA030948, HPA030949" Approved Approved Nucleoplasm,Microtubules,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 36: Choroid plexus - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 9: T-cells - Adaptive immunity: Regulation" 2 "Nucleoplasm, Microtubules, Cytosol" "CAB026378: , HPA030948: , HPA030949: " "unprognostic (5.45e-2)" "unprognostic (6.74e-2)" "unprognostic (3.98e-3)" "unprognostic (4.24e-2)" "unprognostic (2.25e-3)" "unprognostic (1.97e-1)" "unprognostic (2.90e-1)" "unprognostic (7.45e-2)" "unprognostic (7.24e-3)" "potential prognostic favorable (4.66e-6)" "unprognostic (1.35e-2)" "potential prognostic favorable (5.38e-6)" "unprognostic (9.29e-2)" "unprognostic (3.83e-2)" "unprognostic (1.43e-2)" "unprognostic (1.05e-1)" "unprognostic (2.11e-1)" "unprognostic (7.58e-2)" "unprognostic (2.41e-1)" "validated prognostic unfavorable (8.61e-4)" "validated prognostic unfavorable (7.37e-4)" "unprognostic (5.76e-2)" "unprognostic (3.80e-3)" "unprognostic (3.05e-1)" "unprognostic (1.76e-1)" "unprognostic (1.15e-1)" "unprognostic (1.52e-1)" "unprognostic (6.60e-2)" "unprognostic (2.19e-1)" CRYBG2 "AIM1L, FLJ38020" ENSG00000176092 "Crystallin beta-gamma domain containing 2" Q8N1P7 1 26321698-26360080 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "cervix: 19.0;esophagus: 61.7;skin 1: 22.8;vagina: 24.3" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 455.7;Esophageal basal cells: 47.7;Esophageal suprabasal cells: 172.3;Ocular epithelial cells: 114.3;Prostatic hillock cells: 68.2;Suprabasal keratinocytes: 97.3;Syncytiotrophoblasts: 120.1;Urothelial cells: 109.2" "Cell type enriched" "Detected in single" 5 "leukocyte: 5.8" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 21.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 15.0" "Colon - Colon enterocytes, Prostate - Urothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA029629 Approved Nucleoplasm NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 5 Nucleoplasm "HPA029629: " "unprognostic (1.11e-1)" "unprognostic (7.29e-3)" "unprognostic (3.40e-1)" "unprognostic (1.03e-2)" "unprognostic (2.28e-1)" "potential prognostic unfavorable (1.94e-4)" "unprognostic (5.88e-2)" "unprognostic (1.69e-1)" "unprognostic (7.86e-2)" "unprognostic (1.63e-1)" "unprognostic (8.52e-2)" "potential prognostic unfavorable (4.22e-4)" "unprognostic (2.19e-1)" "unprognostic (6.70e-2)" "unprognostic (7.46e-2)" "unprognostic (1.97e-1)" "unprognostic (1.46e-2)" "unprognostic (4.49e-1)" "unprognostic (1.74e-2)" CRYBG3 DKFZp667G2110 ENSG00000080200 "Crystallin beta-gamma domain containing 3" Q68DQ2 3 97822011-97944984 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 25.0" "Cell type enhanced" "Detected in many" "Renal collecting duct intercalated cells: 263.3;Retinal bipolar cells: 269.3" "Cell type enhanced" "Detected in all" "mammillary body: 311.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 3.6" "Group enriched" "Detected in many" 8 "dendritic cells: 3.6;granulocytes: 1.5;monocytes: 1.4" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075635 Approved "Plasma membrane,Primary cilium" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 1: Neuronal - Visual perception" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 9 "Plasma membrane" "Primary cilium" "HPA075635: " "unprognostic (8.91e-2)" "unprognostic (6.14e-2)" "unprognostic (1.08e-1)" "unprognostic (3.34e-3)" "unprognostic (1.09e-1)" "unprognostic (2.63e-2)" "unprognostic (8.73e-2)" "unprognostic (4.88e-2)" "unprognostic (3.73e-2)" "potential prognostic unfavorable (8.80e-4)" "potential prognostic favorable (7.63e-5)" "unprognostic (1.01e-1)" "unprognostic (1.26e-1)" "unprognostic (8.15e-2)" "unprognostic (2.08e-3)" "unprognostic (4.85e-1)" "unprognostic (1.58e-1)" "unprognostic (5.69e-2)" "unprognostic (2.81e-2)" "unprognostic (1.46e-2)" "unprognostic (1.31e-1)" "unprognostic (1.82e-1)" "unprognostic (9.64e-2)" "unprognostic (7.47e-2)" "unprognostic (1.07e-1)" "unprognostic (4.92e-2)" "unprognostic (1.30e-1)" "unprognostic (2.04e-3)" "unprognostic (7.92e-2)" CRYGA "CRY-g-A, CRYG1, CRYG5" ENSG00000168582 "Crystallin gamma A" P11844 2 208160740-208163589 "Predicted intracellular proteins" "Eye lens protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Megakaryocyte progenitors: 3.6;Oligodendrocyte progenitor cells: 1.3" "Low cell type specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA043386 Supported Uncertain Vesicles,Cytosol NA NA "Cluster 35: Neurons - Synaptic function & neurogenesis" "Vesicles, Cytosol" "HPA043386: " CRYGB CRYG2 ENSG00000182187 "Crystallin gamma B" P07316 2 208142573-208146158 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Eye lens protein" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 4 "Early spermatids: 2.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Ovary Serous Cystadenocarcinoma (TCGA): 1.3;Testicular Germ Cell Tumor (TCGA): 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "hippocampal formation: 3.3;hypothalamus: 2.2;thalamus: 2.0" HPA043386 Supported Approved Vesicles,Cytosol NA NA "Cluster 1: Neuronal - Visual perception" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 1 "Vesicles, Cytosol" "HPA043386: " "unprognostic (5.54e-2)" "unprognostic (4.36e-2)" CRYGC CRYG3 ENSG00000163254 "Crystallin gamma C" P07315 2 208128137-208129828 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Eye lens protein" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 13 "testis: 1.6" "Cell type enhanced" "Detected in some" "Late primary spermatocytes: 3.6;Late spermatids: 1.1;Undifferentiated spermatogonia: 2.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Ovary Serous Cystadenocarcinoma (TCGA): 1.0;Uterine Corpus Endometrial Carcinoma (TCGA): 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 20 "hippocampal formation: 3.2;hypothalamus: 1.5;thalamus: 1.2" "Group enriched" "Detected in some" 17 "cerebral cortex: 1.5;hippocampal formation: 1.7" HPA043386 Supported Approved Vesicles,Cytosol NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 11 "Vesicles, Cytosol" "HPA043386: " "unprognostic (1.03e-1)" CRYGD CRYG4 ENSG00000118231 "Crystallin gamma D" P07320 2 208121607-208124524 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Eye lens protein" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.1;ovary: 7.7" "Cell type enhanced" "Detected in some" "Early spermatids: 6.1;Hematopoietic stem cells: 11.6;Late primary spermatocytes: 2.6;Late spermatids: 2.0;Megakaryocyte progenitors: 5.2;Megakaryocyte-Erythroid progenitors: 4.5;Müller glia: 1.9;Other brain neurons: 1.9;Ovarian stromal cells: 10.9;Thymocytes: 2.5" "Cell type enhanced" "Detected in some" "lower rhombic lip: 2.9" "Cancer enriched" "Detected in some" 9 "Testicular Germ Cell Tumor (TCGA): 10.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Neuroblastoma: 2.5" "Pituitary gland - Thyrotropes" "Not detected" "Not detected" "HPA041269, HPA043386" Supported Approved Vesicles,Cytosol NA NA "Cluster 75: Ovary - Mixed function" "Cluster 24: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 94: Gonadal somatic cells - Mixed function" 3 "Vesicles, Cytosol" "HPA041269: , HPA043386: " "unprognostic (9.59e-2)" "unprognostic (2.86e-1)" "unprognostic (2.22e-1)" CRYGN ENSG00000127377 "Crystallin gamma N" Q8WXF5 7 151428832-151440813 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "thyroid gland: 15.3" "Cell type enhanced" "Detected in some" "Decidual stromal cells: 9.2;Fibroblasts: 1.2;Müller glia: 1.3;Pericytes: 1.6;Pituicytes/FSCs: 2.8;Pituitary stem cells: 2.1;Retinal pigment epithelial cells: 8.5" "Cell type enriched" "Detected in single" 7 "fibroblast: 4.7" "Cancer enriched" "Detected in some" 32 "Thyroid Carcinoma (TCGA): 41.5" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "memory CD4 T-cell: 1.1;naive CD4 T-cell: 1.1" "Lineage enriched" "Detected in single" 11 "T-cells: 1.1" "Not detected" "Not detected" "Colon - Enteric glia cells, Kidney - Fibroblasts" "Group enriched" "Detected in many" 5 "basal ganglia: 9.1;white matter: 11.4" "Not detected" "Not detected" HPA050788 Uncertain NA NA "Cluster 33: Thyroid gland - Tissue development" "Cluster 23: Choroid plexus - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" 7 "HPA050788: " "unprognostic (2.75e-1)" "unprognostic (2.30e-3)" "unprognostic (6.88e-2)" "unprognostic (2.07e-3)" "unprognostic (5.09e-2)" CRYGS CRYG8 ENSG00000213139 "Crystallin gamma S" P22914 3 186538441-186546702 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Eye lens protein" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.6" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 12.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA035103, HPA063539" Supported Uncertain Cytosol NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 2: Neurons - Nucleosome" "Cluster 56: Non-specific - Sensory perception" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 2 Cytosol "HPA035103: , HPA063539: " "unprognostic (3.55e-2)" "unprognostic (1.35e-1)" "unprognostic (9.52e-3)" "potential prognostic favorable (5.41e-4)" "unprognostic (2.19e-2)" "unprognostic (5.65e-2)" "unprognostic (1.22e-1)" "potential prognostic unfavorable (5.37e-10)" "unprognostic (1.83e-3)" "unprognostic (6.22e-2)" "unprognostic (2.46e-3)" "unprognostic (1.54e-1)" "unprognostic (8.50e-2)" "unprognostic (2.10e-2)" "unprognostic (1.39e-2)" "unprognostic (2.30e-1)" "unprognostic (1.52e-2)" "potential prognostic favorable (3.23e-4)" "unprognostic (2.79e-3)" "unprognostic (1.96e-1)" "unprognostic (1.70e-1)" "unprognostic (1.26e-1)" "unprognostic (2.97e-2)" CRYL1 "GDH, lambda-CRY, MGC149525, MGC149526" ENSG00000165475 "Crystallin lambda 1" Q9Y2S2 13 20403666-20525873 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 307.7;liver: 237.5" "Cell type enhanced" "Detected in many" "Enterocytes: 574.8;Hepatocytes: 448.7;Proximal tubule cells: 573.0;Renal collecting duct intercalated cells: 237.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Spleen - Macrophages, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040403, HPA058848" Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Plasma membrane" NA NA 990000 "Cluster 33: Non-specific - ATP binding" "Cluster 76: Non-specific - Metabolism" "Cluster 27: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 88: Proximal tubular cells - Transmembrane transport" "Nucleoplasm, Nucleoli" "Golgi apparatus, Plasma membrane" "HPA040403: , HPA058848: " "unprognostic (5.80e-2)" "unprognostic (2.31e-2)" "unprognostic (7.77e-2)" "unprognostic (3.52e-2)" "unprognostic (1.68e-1)" "unprognostic (8.00e-2)" "unprognostic (3.04e-1)" "unprognostic (4.62e-1)" "unprognostic (1.16e-1)" "unprognostic (1.55e-1)" "potential prognostic favorable (2.44e-15)" "unprognostic (8.96e-3)" "potential prognostic favorable (3.16e-6)" "unprognostic (5.63e-3)" "unprognostic (3.05e-2)" "unprognostic (3.76e-3)" "unprognostic (1.49e-1)" "unprognostic (6.08e-2)" "unprognostic (1.56e-1)" "unprognostic (4.58e-2)" "unprognostic (1.68e-1)" "unprognostic (6.23e-2)" "unprognostic (2.47e-2)" "unprognostic (2.54e-1)" "unprognostic (4.44e-2)" "potential prognostic unfavorable (4.82e-4)" "unprognostic (1.06e-1)" "unprognostic (1.98e-1)" "unprognostic (1.90e-1)" "unprognostic (1.44e-1)" "unprognostic (1.87e-1)" CRYM DFNA40 ENSG00000103316 "Crystallin mu" Q14894 16 21238874-21303083 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 302.3;heart muscle: 164.0" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 88.0;Brain inhibitory neurons: 53.8;Conjunctival goblet cells: 27.2;Melanocytes: 44.2;Müller glia: 46.7;Pituicytes/FSCs: 50.9;Platelets: 66.2;Prostatic club cells: 30.5;Proximal tubule cells: 44.3;Respiratory secretory cells: 28.9" "Cell type enhanced" "Detected in all" "deep-layer near-projecting: 447.7" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 64.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 21 "plasmacytoid DC: 82.1" "Lineage enriched" "Detected in many" 21 "dendritic cells: 82.1" "Cancer enhanced" "Detected in many" "prostate cancer: 38.8;Rhabdoid: 40.6" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Minor Salivary Gland - Minor salivary glandular cells, Thyroid gland - Fibroblasts" "Group enriched" "Detected in all" 11 "amygdala: 124.1;basal ganglia: 275.2;cerebral cortex: 124.7;hippocampal formation: 324.5;white matter: 128.5" "Low region specificity" "Detected in all" "HPA019086, HPA030619" Enhanced Supported Cytosol NA NA 76000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 35: Non-specific - Mixed function" "Cluster 34: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 3 Cytosol "HPA019086: , HPA030619: " "unprognostic (4.40e-3)" "unprognostic (1.45e-1)" "unprognostic (4.59e-1)" "unprognostic (1.51e-2)" "unprognostic (8.55e-2)" "potential prognostic favorable (1.07e-4)" "unprognostic (9.47e-2)" "unprognostic (1.50e-1)" "unprognostic (4.14e-2)" "unprognostic (1.73e-1)" "potential prognostic favorable (9.94e-6)" "unprognostic (6.30e-2)" "unprognostic (3.87e-2)" "unprognostic (2.19e-1)" "unprognostic (1.50e-3)" "unprognostic (7.49e-3)" "unprognostic (8.59e-2)" "unprognostic (4.13e-1)" "unprognostic (1.12e-1)" "unprognostic (1.56e-1)" "unprognostic (2.32e-2)" "unprognostic (4.73e-2)" "unprognostic (1.11e-1)" "unprognostic (4.29e-2)" "unprognostic (4.80e-3)" "unprognostic (1.04e-1)" "unprognostic (2.07e-2)" "unprognostic (3.77e-2)" "unprognostic (6.88e-3)" CRYZ ENSG00000116791 "Crystallin zeta" Q08257 1 74705482-74733408 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Oxidoreductase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 308.8;liver: 264.3" "Cell type enhanced" "Detected in many" "Epididymal efferent duct absorptive cells: 117.6;Epididymal efferent duct ciliated cells: 131.4;Epididymal principal cells: 105.8;Hepatocytes: 261.1;Oocytes: 262.5" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 77.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021921, HPA023290" Approved Supported Cytosol NA NA 3800000 "Cluster 16: Non-specific - Cell proliferation" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 15: Kidney cancer - Membrane components" "Cluster 93: Hepatocytes - Bile production & excretion" 5 Cytosol "HPA021921: , HPA023290: " "unprognostic (2.50e-1)" "unprognostic (3.15e-2)" "unprognostic (1.32e-1)" "unprognostic (1.03e-1)" "unprognostic (4.65e-2)" "unprognostic (1.04e-1)" "unprognostic (1.50e-2)" "unprognostic (1.31e-3)" "unprognostic (3.71e-2)" "unprognostic (1.60e-2)" "potential prognostic favorable (5.26e-11)" "unprognostic (4.41e-2)" "unprognostic (3.79e-2)" "unprognostic (2.04e-2)" "unprognostic (8.21e-2)" "unprognostic (1.63e-2)" "unprognostic (1.43e-1)" "unprognostic (1.54e-2)" "unprognostic (1.37e-1)" "unprognostic (1.89e-1)" "unprognostic (8.13e-2)" "unprognostic (3.57e-3)" "unprognostic (3.77e-1)" "unprognostic (2.23e-1)" "unprognostic (2.65e-2)" "unprognostic (2.55e-1)" "unprognostic (5.55e-2)" "unprognostic (1.57e-1)" "unprognostic (1.73e-1)" "unprognostic (9.00e-2)" "unprognostic (2.59e-1)" CRYZL1 "4P11, QOH-1" ENSG00000205758 "Crystallin zeta like 1" O95825 21 33589341-33643926 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 28.3;Late primary spermatocytes: 71.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019120, HPA029399, CAB034129" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 73: Brain - Neuronal signaling" "Cluster 31: Non-specific - Transcription" "Cluster 47: Leukemia - Hemostasis" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 11 "Nucleoplasm, Cytosol" "CAB034129: , HPA019120: , HPA029399: " "unprognostic (3.05e-2)" "unprognostic (1.18e-1)" "unprognostic (5.58e-2)" "unprognostic (1.24e-1)" "unprognostic (8.94e-2)" "unprognostic (1.41e-1)" "unprognostic (2.73e-1)" "unprognostic (4.28e-2)" "unprognostic (2.97e-2)" "unprognostic (5.25e-3)" "potential prognostic favorable (1.91e-5)" "unprognostic (5.37e-2)" "unprognostic (8.23e-2)" "unprognostic (1.01e-2)" "unprognostic (1.20e-1)" "unprognostic (1.37e-1)" "unprognostic (2.59e-2)" "unprognostic (1.04e-1)" "unprognostic (4.08e-2)" "unprognostic (1.51e-1)" "unprognostic (3.60e-2)" "unprognostic (2.34e-1)" "unprognostic (2.81e-2)" "unprognostic (1.53e-2)" "unprognostic (1.58e-2)" "unprognostic (9.56e-2)" "unprognostic (1.79e-1)" "unprognostic (1.20e-2)" "unprognostic (6.64e-2)" "unprognostic (1.79e-1)" "unprognostic (2.68e-2)" CS ENSG00000062485 "Citrate synthase" O75390 12 56271699-56300391 "Citric acid cycle related proteins, Enzymes, Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Tricarboxylic acid cycle" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 515.2;tongue: 561.0" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038460, HPA038461, CAB075750, CAB075751, CAB075752, CAB075753, CAB075754" Enhanced Enhanced Mitochondria NA NA 850000 "Cluster 29: Non-specific - Unknown function" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 38: Non-specific - Transcription" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 190 Mitochondria "CAB075750: , CAB075751: , CAB075752: , CAB075753: , CAB075754: , HPA038460: , HPA038461: " "unprognostic (4.34e-2)" "unprognostic (4.60e-3)" "unprognostic (1.33e-1)" "unprognostic (1.80e-1)" "unprognostic (1.08e-2)" "unprognostic (1.33e-1)" "unprognostic (9.11e-2)" "unprognostic (1.82e-1)" "unprognostic (5.50e-2)" "unprognostic (8.37e-3)" "potential prognostic favorable (2.13e-7)" "unprognostic (2.54e-2)" "unprognostic (8.58e-2)" "unprognostic (1.43e-2)" "unprognostic (7.80e-3)" "unprognostic (2.35e-2)" "potential prognostic unfavorable (6.51e-4)" "unprognostic (2.03e-1)" "unprognostic (1.19e-1)" "unprognostic (1.76e-1)" "unprognostic (1.23e-1)" "unprognostic (5.81e-2)" "unprognostic (5.31e-2)" "unprognostic (5.60e-2)" "unprognostic (2.66e-2)" "unprognostic (9.52e-2)" "unprognostic (5.50e-2)" "unprognostic (1.45e-1)" "unprognostic (1.09e-1)" "unprognostic (1.07e-2)" "unprognostic (1.73e-2)" CSAD "CSD, PCAP" ENSG00000139631 "Cysteine sulfinic acid decarboxylase" Q9Y600 12 53157663-53180925 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 239.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 16.2" "Lineage enriched" "Detected in all" 5 "granulocytes: 16.2" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039487, HPA079296" Approved Approved "Endoplasmic reticulum,Vesicles,Plasma membrane" NA NA 5800 "Cluster 20: Non-specific - DNA binding" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 11: White matter - Signal transduction" "Cluster 27: Breast cancer - Unknown function" "Cluster 89: Adipocytes - Lipid metabolism" 1 "Endoplasmic reticulum, Vesicles, Plasma membrane" "HPA039487: , HPA079296: " "unprognostic (9.05e-2)" "unprognostic (1.53e-1)" "unprognostic (1.41e-1)" "unprognostic (8.46e-2)" "unprognostic (8.49e-3)" "unprognostic (2.57e-1)" "unprognostic (3.47e-2)" "unprognostic (7.35e-2)" "unprognostic (3.80e-3)" "unprognostic (2.80e-1)" "potential prognostic unfavorable (3.83e-5)" "unprognostic (1.22e-1)" "unprognostic (3.83e-2)" "validated prognostic favorable (1.09e-4)" "validated prognostic favorable (5.08e-4)" "unprognostic (8.00e-3)" "unprognostic (4.00e-1)" "unprognostic (4.22e-2)" "unprognostic (3.74e-2)" "unprognostic (1.92e-1)" "unprognostic (4.90e-3)" "potential prognostic favorable (2.46e-4)" "potential prognostic unfavorable (9.89e-4)" "unprognostic (5.33e-2)" "unprognostic (5.74e-2)" "unprognostic (2.68e-2)" "unprognostic (4.32e-2)" "unprognostic (2.83e-2)" "unprognostic (1.88e-1)" "unprognostic (2.44e-1)" "unprognostic (6.17e-2)" CSAG1 "CSAGE, CT24.1" ENSG00000198930 "Chondrosarcoma associated gene 1" Q6PB30 X 152727484-152733735 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 4 "brain: 1.9;testis: 1.2" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 11.2;Early primary spermatocytes: 5.5;Gastric progenitor cells: 6.4;Pericytes: 2.6;Undifferentiated spermatogonia: 8.7" "Cell type enriched" "Detected in some" 5 "pericyte: 13.8" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 27.2" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 88.0" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 106: Spermatogonia - Spermatogonial differentiation" "unprognostic (2.19e-2)" "unprognostic (3.13e-1)" "unprognostic (1.24e-1)" "unprognostic (6.17e-2)" "unprognostic (6.14e-2)" "unprognostic (1.68e-1)" "unprognostic (2.68e-1)" "unprognostic (4.72e-1)" "potential prognostic unfavorable (5.23e-4)" "unprognostic (3.48e-2)" "unprognostic (2.16e-1)" "unprognostic (4.19e-1)" "unprognostic (2.55e-1)" "unprognostic (1.45e-1)" "unprognostic (6.99e-3)" "unprognostic (7.69e-1)" "unprognostic (2.11e-1)" "unprognostic (1.99e-2)" "unprognostic (7.95e-2)" "unprognostic (6.44e-2)" CSAG2 "CSAG3B, CT24.2, TRAG3" ENSG00000268902 "CSAG family member 2" X 152708261-152714549 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Gallbladder cancer: 23.0" NA NA "Cluster 18: Lymphoid tissue - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 3: Early primary spermatocytes - Early meiosis" "unprognostic (4.78e-3)" "unprognostic (2.93e-2)" "unprognostic (8.05e-2)" "potential prognostic favorable (1.53e-4)" "unprognostic (3.36e-2)" "unprognostic (1.58e-3)" "unprognostic (3.74e-3)" "unprognostic (2.78e-1)" "potential prognostic favorable (4.96e-4)" "unprognostic (1.59e-2)" "unprognostic (2.35e-1)" "unprognostic (3.78e-1)" "unprognostic (1.35e-2)" CSAG3 CSAG3A ENSG00000268916 "CSAG family member 3" Q9Y5P2 X 152753921-152760222 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 2.1;testis: 3.9" "Cell type enhanced" "Detected in single" "Early primary spermatocytes: 2.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Urothelial cells" NA NA "Cluster 39: Testis - Nuclear processes" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 3: Early primary spermatocytes - Early meiosis" 1 "unprognostic (8.58e-2)" "unprognostic (8.65e-2)" "unprognostic (4.35e-1)" "unprognostic (1.35e-2)" "unprognostic (1.70e-1)" "unprognostic (2.50e-3)" "unprognostic (3.23e-2)" "unprognostic (1.65e-1)" "unprognostic (1.83e-1)" "unprognostic (9.19e-3)" "unprognostic (4.90e-2)" "unprognostic (2.57e-1)" "unprognostic (2.27e-1)" "unprognostic (8.21e-2)" "unprognostic (3.72e-2)" "unprognostic (1.52e-1)" "unprognostic (1.36e-1)" CSDC2 PIPPin ENSG00000172346 "Cold shock domain containing C2" Q9Y534 22 41561010-41577741 "Predicted intracellular proteins" "mRNA processing" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 154.3;heart muscle: 300.6;ovary: 142.9" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 74.9;Bergmann glia: 64.7;Cardiomyocytes: 118.3;Decidual stromal cells: 81.1;Müller glia: 86.5;Ovarian stromal cells: 148.4;Podocytes: 60.9;Proximal tubule cells: 40.7;Retinal amacrine cells: 46.7;Retinal ganglion cells: 57.9;Sertoli cells: 77.9;Vascular smooth muscle cells: 76.3" "Cell type enhanced" "Detected in all" "Bergmann glia: 78.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 5.6" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Spleen - Smooth muscle cells, Testis - Sertoli cells, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003073, HPA076549" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 44: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 94: Gonadal somatic cells - Mixed function" 3 Nucleoplasm Cytosol "HPA003073: , HPA076549: " "unprognostic (1.23e-2)" "unprognostic (1.29e-1)" "unprognostic (5.64e-2)" "unprognostic (2.24e-3)" "unprognostic (1.06e-2)" "unprognostic (4.01e-2)" "unprognostic (3.98e-1)" "unprognostic (1.52e-3)" "unprognostic (2.36e-1)" "unprognostic (2.12e-3)" "unprognostic (1.68e-1)" "unprognostic (4.13e-3)" "unprognostic (1.69e-3)" "unprognostic (1.14e-1)" "unprognostic (9.27e-3)" "unprognostic (4.49e-2)" "unprognostic (5.79e-2)" "unprognostic (8.72e-2)" "unprognostic (1.93e-2)" "unprognostic (1.04e-1)" "unprognostic (1.88e-1)" "unprognostic (2.39e-3)" "unprognostic (8.79e-3)" "unprognostic (5.10e-3)" "unprognostic (8.98e-2)" "unprognostic (5.38e-2)" CSDE1 "D1S155E, UNR" ENSG00000009307 "Cold shock domain containing E1" O75534 1 114716913-114758676 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 1250.0" "Cell type enhanced" "Detected in all" "Late spermatids: 939.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018846, HPA052221" Supported Supported "Endoplasmic reticulum,Golgi apparatus,Plasma membrane,Cytosol" NA NA 61000 "Cluster 28: Neutrophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 62: Smooth muscle cells - Muscle contraction" 26 Cytosol "Endoplasmic reticulum, Golgi apparatus, Plasma membrane" "HPA018846: , HPA052221: " "unprognostic (4.63e-2)" "unprognostic (2.95e-1)" "unprognostic (1.97e-1)" "unprognostic (4.49e-2)" "unprognostic (9.60e-3)" "unprognostic (1.34e-1)" "unprognostic (4.93e-2)" "unprognostic (1.04e-1)" "unprognostic (1.14e-1)" "unprognostic (4.40e-3)" "validated prognostic favorable (5.14e-7)" "validated prognostic favorable (2.39e-6)" "unprognostic (1.25e-1)" "unprognostic (1.75e-3)" "unprognostic (2.15e-2)" "unprognostic (2.63e-3)" "unprognostic (1.54e-2)" "unprognostic (1.94e-1)" "unprognostic (3.60e-1)" "unprognostic (1.10e-1)" "unprognostic (1.52e-1)" "potential prognostic unfavorable (3.03e-4)" "unprognostic (2.12e-1)" "unprognostic (1.27e-1)" "unprognostic (2.14e-3)" "unprognostic (8.45e-2)" "unprognostic (2.57e-1)" "unprognostic (1.26e-2)" "unprognostic (4.80e-1)" "unprognostic (2.06e-3)" "unprognostic (3.61e-2)" CSE1L "CAS, CSE1, XPO2" ENSG00000124207 "Chromosome segregation 1 like" P55060 20 49046246-49096960 "Cancer-related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early primary spermatocytes: 198.0;Erythrocyte progenitors: 182.6;Late primary spermatocytes: 199.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002140, HPA038059, HPA038060" Enhanced Enhanced Nucleoplasm,Cytosol No Yes 530000 "Cluster 33: Non-specific - ATP binding" "Cluster 39: Testis - Nuclear processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 27: Non-specific - Cell proliferation" 61 Nucleoplasm Cytosol "CAB002140: , HPA038059: , HPA038060: " "unprognostic (1.22e-2)" "unprognostic (1.88e-3)" "unprognostic (2.67e-1)" "unprognostic (1.19e-3)" "unprognostic (1.80e-1)" "unprognostic (8.35e-2)" "unprognostic (3.43e-1)" "unprognostic (1.22e-1)" "unprognostic (7.05e-2)" "unprognostic (1.28e-2)" "potential prognostic favorable (4.41e-5)" "unprognostic (2.70e-1)" "unprognostic (7.83e-3)" "validated prognostic unfavorable (2.93e-6)" "validated prognostic unfavorable (4.19e-4)" "potential prognostic unfavorable (1.84e-4)" "unprognostic (2.45e-3)" "unprognostic (1.23e-1)" "unprognostic (1.55e-1)" "unprognostic (1.63e-1)" "unprognostic (2.92e-3)" "potential prognostic unfavorable (8.84e-4)" "unprognostic (1.14e-2)" "unprognostic (3.12e-2)" "potential prognostic favorable (8.00e-4)" "unprognostic (1.31e-2)" "unprognostic (1.70e-1)" "unprognostic (2.71e-1)" "unprognostic (2.66e-1)" "unprognostic (1.27e-1)" "unprognostic (9.42e-2)" CSF1 "M-CSF, MCSF, MGC31930" ENSG00000184371 "Colony stimulating factor 1" P09603 1 109910242-109930992 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Immunity, Inflammatory response, Innate immunity" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 101.5;Fibroblasts: 73.2;Mast cells: 343.1;Megakaryocyte progenitors: 125.9;Megakaryocyte-Erythroid progenitors: 451.5;Pancreatic duct cells: 107.7;Schwann cells: 75.3" "Cell type enhanced" "Detected in many" "fibroblast: 159.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "basophil: 13.2;eosinophil: 22.3" "Lineage enriched" "Detected in many" 16 "granulocytes: 22.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076624 Supported "Nuclear bodies,Plasma membrane" "Secreted to blood" Cytokine NA NA 270000 8800000 "Cluster 19: Eosinophils - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 58: Mast cells - Allergic inflammatory responses" 7 "Plasma membrane" "Nuclear bodies" "HPA076624: " "unprognostic (1.23e-1)" "unprognostic (8.11e-3)" "unprognostic (1.84e-1)" "unprognostic (7.29e-2)" "unprognostic (6.91e-2)" "unprognostic (5.69e-2)" "unprognostic (3.33e-1)" "unprognostic (3.65e-3)" "unprognostic (5.63e-2)" "unprognostic (1.70e-1)" "unprognostic (2.94e-3)" "unprognostic (1.33e-1)" "unprognostic (8.42e-2)" "potential prognostic unfavorable (2.14e-5)" "unprognostic (1.09e-1)" "unprognostic (1.45e-1)" "unprognostic (6.52e-3)" "unprognostic (1.59e-1)" "unprognostic (1.09e-1)" "unprognostic (4.91e-2)" "unprognostic (4.26e-1)" "unprognostic (3.59e-1)" "unprognostic (1.83e-2)" "unprognostic (7.50e-2)" "unprognostic (9.71e-2)" "unprognostic (5.82e-3)" "unprognostic (8.95e-3)" "unprognostic (8.24e-2)" "unprognostic (3.04e-2)" "unprognostic (2.72e-1)" "unprognostic (4.02e-2)" CSF1R "C-FMS, CD115, CSFR, FMS" ENSG00000182578 "Colony stimulating factor 1 receptor" P07333 5 150053291-150113372 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Neurodegeneration, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 106.8;placenta: 97.1" "Cell type enhanced" "Detected in many" "cDC: 124.0;Extravillous trophoblasts: 226.4;Hofbauer cells: 647.5;Kupffer cells: 438.7;Macrophages: 330.0;Microglia: 701.8;monocytes: 160.2;Retinal pigment epithelial cells: 102.3" "Cell type enriched" "Detected in many" 17 "central nervous system macrophage: 840.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 444.5;non-classical monocyte: 650.1" "Lineage enriched" "Detected in many" 5 "monocytes: 650.1" "Cancer enhanced" "Detected in many" "Leukemia: 13.3" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Langerhans cells, Spleen - Macrophages, Testis - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008970, HPA012323" Approved Supported "Vesicles,Plasma membrane" "Intracellular and membrane" Receptor NA NA 220000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 19 "Vesicles, Plasma membrane" "CAB008970: , HPA012323: " "unprognostic (1.28e-1)" "unprognostic (6.19e-2)" "unprognostic (2.37e-1)" "unprognostic (1.20e-1)" "unprognostic (2.53e-2)" "unprognostic (1.16e-1)" "unprognostic (9.78e-2)" "unprognostic (1.01e-1)" "unprognostic (8.10e-2)" "unprognostic (3.68e-1)" "unprognostic (1.41e-2)" "unprognostic (9.98e-2)" "unprognostic (6.89e-2)" "unprognostic (5.10e-2)" "unprognostic (8.87e-2)" "unprognostic (2.73e-3)" "unprognostic (1.93e-2)" "unprognostic (3.91e-2)" "unprognostic (7.55e-2)" "unprognostic (2.76e-2)" "unprognostic (9.96e-2)" "unprognostic (2.65e-1)" "unprognostic (1.50e-1)" "unprognostic (1.44e-1)" "unprognostic (1.88e-2)" "unprognostic (2.01e-2)" "unprognostic (9.85e-2)" "unprognostic (3.02e-2)" "potential prognostic unfavorable (5.12e-4)" "unprognostic (3.95e-3)" "unprognostic (2.40e-1)" CSF2 "GM-CSF, GMCSF" ENSG00000164400 "Colony stimulating factor 2" P04141 5 132073789-132076170 "Cancer-related genes, Predicted secreted proteins" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lung: 1.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 15.2;Endometrial secretory cells: 3.6;Innate lymphoid cells: 59.2;Mast cells: 13.9;NK-cells: 8.1;T-cells: 18.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 8.0" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 12 "NK-cell: 6.3" "Lineage enriched" "Detected in single" 12 "NK-cells: 6.3" "Cancer enhanced" "Detected in many" "Bile duct cancer: 27.2;Kidney cancer: 31.4" "Lung - Alveolar cells type 2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA057404, HPA062006" Enhanced Vesicles "Secreted to blood" Cytokine NA NA 23900 "Cluster 15: NK-cells - Unknown function" "Cluster 13: Lung - Secretion" "Cluster 59: Leukemia - T-cell receptor" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 4 Vesicles "HPA057404: , HPA062006: " "unprognostic (1.05e-3)" "unprognostic (5.93e-2)" "unprognostic (2.47e-1)" "unprognostic (4.29e-1)" "unprognostic (2.06e-3)" "potential prognostic favorable (8.91e-4)" "unprognostic (2.40e-1)" "unprognostic (4.07e-3)" "unprognostic (5.74e-3)" "unprognostic (4.25e-3)" "unprognostic (5.69e-2)" "unprognostic (1.11e-2)" "unprognostic (1.28e-1)" "unprognostic (2.39e-2)" "unprognostic (6.94e-2)" CSF2RA "alphaGMR, CD116, CSF2R" ENSG00000198223 "Colony stimulating factor 2 receptor subunit alpha" P15509 X 1268800-1310381 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Receptor "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 59.9" "Cell type enhanced" "Detected in many" "cDC: 771.2;Cytotrophoblasts: 425.8;Extravillous trophoblasts: 237.0;Hofbauer cells: 158.7;Macrophages: 349.2;Migrating cytotrophoblasts: 410.4;monocytes: 323.7;Neutrophil progenitors: 156.6;Neutrophils: 750.1;pDCs: 189.1;Syncytiotrophoblasts: 523.6" "Cell type enriched" "Detected in single" 8 "central nervous system macrophage: 4.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 319.8" "Group enriched" "Detected in all" 29 "dendritic cells: 170.1;granulocytes: 319.8;monocytes: 160.9" "Cancer enriched" "Detected in many" 7 "Adrenocortical cancer: 111.7" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Macrophages, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Skeletal muscle - Macrophages, Spleen - Neutrophils_2, Stomach - Macrophages, Thyroid gland - T-cells" "Low region specificity" "Detected in single" CAB016148 Uncertain "Secreted to blood" Receptor NA NA 710000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 34: Testis cancer - Unknown function" "Cluster 82: Dendritic cells - Antigen presentation" 2 "CAB016148: " "unprognostic (2.91e-1)" "unprognostic (2.09e-1)" "unprognostic (1.85e-2)" "potential prognostic favorable (1.75e-4)" "unprognostic (4.20e-2)" "unprognostic (1.43e-1)" "unprognostic (2.82e-1)" "potential prognostic favorable (8.00e-4)" "unprognostic (8.58e-2)" "unprognostic (4.83e-3)" "unprognostic (3.35e-1)" "unprognostic (1.84e-1)" "unprognostic (3.77e-2)" "unprognostic (7.06e-2)" "unprognostic (9.07e-3)" "unprognostic (3.80e-2)" "unprognostic (5.23e-2)" "unprognostic (7.11e-3)" "unprognostic (2.25e-1)" "unprognostic (1.76e-1)" "unprognostic (3.31e-3)" "unprognostic (6.19e-2)" "unprognostic (1.07e-3)" "potential prognostic favorable (3.57e-4)" "unprognostic (9.22e-2)" "unprognostic (5.63e-3)" "unprognostic (1.03e-3)" "unprognostic (9.14e-2)" "unprognostic (3.42e-1)" CSF2RB "betaGMR, CD131, IL3RB, IL5RB" ENSG00000100368 "Colony stimulating factor 2 receptor subunit beta" P32927 22 36913628-36940439 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 51.4;lymphoid tissue: 61.8" "Cell type enriched" "Detected in some" 5 "Neutrophils: 511.0" "Group enriched" "Detected in some" 6 "central nervous system macrophage: 15.3;leukocyte: 5.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "basophil: 239.1;neutrophil: 76.3" "Lineage enriched" "Detected in many" 16 "granulocytes: 239.1" "Group enriched" "Detected in some" 47 "Leukemia: 43.7;lymphoma: 16.5;Myeloma: 15.2" "Adrenal gland - Macrophages, Spleen - Neutrophils_2, Testis - Late spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA078677 Approved "Golgi apparatus" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 49: HMC-1 - Innate immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 17 "Golgi apparatus" "HPA078677: " "unprognostic (3.93e-2)" "unprognostic (1.56e-2)" "unprognostic (5.87e-2)" "unprognostic (2.98e-2)" "unprognostic (6.20e-2)" "unprognostic (6.34e-2)" "unprognostic (6.50e-2)" "unprognostic (9.21e-2)" "potential prognostic favorable (4.95e-4)" "unprognostic (3.53e-2)" "unprognostic (2.35e-2)" "unprognostic (4.95e-2)" "unprognostic (6.49e-2)" "unprognostic (1.20e-1)" "unprognostic (1.32e-1)" "potential prognostic favorable (5.00e-4)" "unprognostic (2.38e-1)" "unprognostic (5.43e-2)" "unprognostic (1.09e-1)" "unprognostic (9.58e-2)" "unprognostic (4.46e-1)" "unprognostic (1.18e-1)" "unprognostic (9.71e-3)" "unprognostic (1.35e-1)" "unprognostic (1.25e-1)" "unprognostic (9.41e-2)" "unprognostic (4.39e-1)" "unprognostic (3.74e-2)" "unprognostic (9.69e-2)" "unprognostic (1.93e-1)" "unprognostic (2.35e-1)" CSF3 "C17orf33, G-CSF, GCSF, MGC45931" ENSG00000108342 "Colony stimulating factor 3" P09919 17 40015361-40017813 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 142.1;urinary bladder: 53.4" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 43.8;Conjunctival goblet cells: 23.3;Endometrial secretory cells: 233.7;Fallopian secretory cells: 40.2;Myosatellite cells: 71.7;Vascular endothelial cells: 144.5" "Cell type enhanced" "Detected in single" "endothelial cell: 3.2" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 11.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder cancer: 35.5;Sarcoma: 52.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted to blood" Cytokine NA NA 6170 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 44: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "unprognostic (6.25e-2)" "unprognostic (9.73e-3)" "unprognostic (1.37e-1)" "unprognostic (1.22e-1)" "unprognostic (8.19e-2)" "potential prognostic unfavorable (6.96e-5)" "unprognostic (3.62e-2)" "unprognostic (7.48e-2)" "unprognostic (8.90e-2)" "unprognostic (6.30e-2)" "unprognostic (1.58e-1)" "unprognostic (2.54e-1)" "unprognostic (6.68e-2)" "unprognostic (1.50e-1)" "unprognostic (8.63e-2)" "unprognostic (1.18e-1)" "unprognostic (2.82e-1)" CSF3R "CD114, GCSFR" ENSG00000119535 "Colony stimulating factor 3 receptor" Q99062 1 36466043-36483278 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" Receptor "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 183.7;lung: 134.4;lymphoid tissue: 375.3" "Group enriched" "Detected in many" 5 "Neutrophils: 6775.9;Syncytiotrophoblasts: 3282.6" "Cell type enriched" "Detected in some" 13 "central nervous system macrophage: 410.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 1924.2" "Lineage enriched" "Detected in many" 7 "granulocytes: 1924.2" "Cancer enriched" "Detected in some" 25 "Leukemia: 32.2" "Adipose subcutaneous - Macrophages, Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophils_2, Skeletal muscle - Neutrophils, Spleen - Neutrophils_2, Stomach - Neutrophils, Thyroid gland - Neutrophils" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB017116, HPA048086" Enhanced "Intracellular and membrane" Receptor NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 7 "CAB017116: , HPA048086: " "unprognostic (1.05e-1)" "unprognostic (2.86e-2)" "unprognostic (5.36e-2)" "unprognostic (1.70e-1)" "unprognostic (2.94e-1)" "unprognostic (5.81e-2)" "unprognostic (4.44e-2)" "unprognostic (1.40e-1)" "unprognostic (7.95e-2)" "unprognostic (3.25e-1)" "unprognostic (4.07e-2)" "unprognostic (5.05e-2)" "unprognostic (1.61e-2)" "unprognostic (1.07e-2)" "unprognostic (1.13e-3)" "unprognostic (2.58e-2)" "unprognostic (8.72e-2)" "unprognostic (8.56e-3)" "unprognostic (1.96e-1)" "unprognostic (3.69e-2)" "unprognostic (1.26e-1)" "unprognostic (5.83e-2)" "unprognostic (3.81e-2)" "unprognostic (3.66e-1)" "unprognostic (1.42e-1)" "unprognostic (1.34e-1)" "unprognostic (2.44e-2)" "unprognostic (7.89e-2)" "potential prognostic unfavorable (2.26e-4)" "unprognostic (1.90e-1)" "unprognostic (2.79e-1)" CSGALNACT1 "ChGn, CSGalNAcT-1, FLJ11264" ENSG00000147408 "Chondroitin sulfate N-acetylgalactosaminyltransferase 1" Q8TDX6 8 19404161-19758029 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 70.7" "Cell type enhanced" "Detected in many" "Astrocytes: 889.5;Cardiomyocytes: 755.4;Microglia: 966.1;Monocyte progenitors: 560.5;Neutrophil progenitors: 2572.4;Neutrophils: 2657.9;Oligodendrocyte progenitor cells: 604.3;Prostatic glandular cells: 1418.7" "Cell type enhanced" "Detected in all" "astrocyte: 893.1;central nervous system macrophage: 1308.5" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 54.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 58.0" "Group enriched" "Detected in all" 5 "B-cells: 36.7;granulocytes: 25.2;T-cells: 58.0" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 34.3" "Liver - Hepatic stellate cells, Prostate - Prostate glandular cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA068462 Approved "Golgi apparatus,Cytosol" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 61: Non-specific - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 37: Neutrophil progenitors - Granulopoiesis" Cytosol "Golgi apparatus" "HPA068462: " "unprognostic (7.12e-3)" "unprognostic (1.89e-1)" "unprognostic (9.42e-2)" "unprognostic (6.01e-2)" "unprognostic (2.12e-1)" "unprognostic (2.91e-1)" "unprognostic (1.36e-1)" "unprognostic (3.42e-3)" "unprognostic (6.89e-3)" "unprognostic (2.92e-1)" "potential prognostic favorable (1.30e-4)" "unprognostic (1.34e-3)" "potential prognostic unfavorable (9.64e-4)" "unprognostic (2.02e-1)" "unprognostic (1.03e-1)" "unprognostic (4.94e-3)" "unprognostic (5.26e-2)" "unprognostic (1.18e-1)" "unprognostic (5.32e-2)" "unprognostic (7.16e-2)" "unprognostic (3.07e-2)" "unprognostic (1.02e-2)" "unprognostic (2.46e-1)" "unprognostic (5.92e-2)" "unprognostic (1.38e-1)" "unprognostic (3.00e-2)" "unprognostic (1.98e-1)" "unprognostic (2.31e-2)" "unprognostic (4.80e-2)" "unprognostic (2.04e-3)" "unprognostic (1.34e-2)" CSGALNACT2 "GALNACT-2, GALNACT2, MGC40204, PRO0082" ENSG00000169826 "Chondroitin sulfate N-acetylgalactosaminyltransferase 2" Q8N6G5 10 43138445-43185302 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "bone marrow: 126.5" "Cell type enhanced" "Detected in many" "Monocyte progenitors: 425.0;monocytes: 580.6;Neutrophil progenitors: 1283.4;Neutrophils: 2076.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031540 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 55: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 20 "Endoplasmic reticulum" "HPA031540: " "unprognostic (4.08e-2)" "unprognostic (7.49e-2)" "unprognostic (6.62e-2)" "unprognostic (1.67e-2)" "unprognostic (1.27e-2)" "unprognostic (1.49e-2)" "unprognostic (1.42e-1)" "unprognostic (6.21e-3)" "unprognostic (1.92e-2)" "unprognostic (3.87e-2)" "unprognostic (5.13e-3)" "unprognostic (1.77e-1)" "unprognostic (2.09e-3)" "unprognostic (3.79e-3)" "unprognostic (1.75e-1)" "unprognostic (9.36e-2)" "unprognostic (6.29e-2)" "unprognostic (2.01e-2)" "unprognostic (3.70e-2)" "unprognostic (2.91e-2)" "unprognostic (2.06e-3)" "unprognostic (2.66e-2)" "unprognostic (1.16e-1)" "unprognostic (2.55e-1)" "unprognostic (2.50e-1)" "unprognostic (7.61e-3)" "unprognostic (3.01e-1)" "unprognostic (3.91e-2)" "unprognostic (1.83e-1)" "unprognostic (2.47e-1)" "unprognostic (9.97e-2)" CSH1 "CSA, CSMT, FLJ75407, hCS-A, PL" ENSG00000136488 "Chorionic somatomammotropin hormone 1" P0DML2 17 63894909-63896661 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 250 "placenta: 9234.3" "Group enriched" "Detected in some" 78 "Extravillous trophoblasts: 1043.9;Syncytiotrophoblasts: 794.4" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 131 "Testicular Germ Cell Tumor (TCGA): 13.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 35 "testis cancer: 15.6;Uterine cancer: 8.3" "Pituitary gland - Somatotropes" "CAB026374, HPA043715" Enhanced "Secreted to blood" Hormone NA NA 30000000 "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." 4 "CAB026374: , HPA043715: " "unprognostic (5.92e-2)" CSH2 "CS-2, CSB, hCS-B" ENSG00000213218 "Chorionic somatomammotropin hormone 2" P0DML3 17 63872012-63873766 "Essential proteins, Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 220 "placenta: 3105.6" "Group enriched" "Detected in some" 18 "Extravillous trophoblasts: 32.6;Syncytiotrophoblasts: 128.8" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 32 "Testicular Germ Cell Tumor (TCGA): 3.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 22 "testis cancer: 12.0;Uterine cancer: 8.9" "Pituitary gland - Somatotropes" HPA043715 Supported "Secreted to blood" Hormone NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." 2 "HPA043715: " "unprognostic (1.18e-1)" CSHL1 "CS-5, CSHP1, CSL, hCS-L, MGC149868" ENSG00000204414 "Chorionic somatomammotropin hormone like 1" Q14406 17 63909597-63911341 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 107 "placenta: 141.3" "Cell type enriched" "Detected in some" 8 "Syncytiotrophoblasts: 9.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pituitary gland - Somatotropes" "CAB025646, HPA043715" Enhanced "Secreted to blood" Hormone NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." "CAB025646: , HPA043715: " CSK ENSG00000103653 "C-terminal Src kinase" P41240 15 74782080-74803197 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 158.2" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 201.3;Megakaryocytes: 98.9;monocytes: 122.9;Neutrophils: 178.1;Tuft cells: 149.9" "Cell type enhanced" "Detected in all" "leukocyte: 105.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011203, HPA026488, HPA028425" Approved Approved Enhanced Vesicles,Cytosol No No 580000 "Cluster 25: Non-specific - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 49 "Vesicles, Cytosol" "CAB011203: , HPA026488: , HPA028425: " "unprognostic (3.08e-1)" "unprognostic (9.45e-2)" "unprognostic (2.61e-1)" "unprognostic (1.15e-2)" "unprognostic (8.09e-2)" "unprognostic (7.31e-2)" "unprognostic (1.59e-1)" "unprognostic (2.56e-2)" "unprognostic (3.07e-2)" "unprognostic (3.12e-1)" "unprognostic (2.54e-2)" "unprognostic (2.47e-1)" "unprognostic (3.46e-1)" "unprognostic (1.75e-2)" "unprognostic (5.72e-2)" "unprognostic (1.36e-1)" "unprognostic (2.30e-2)" "unprognostic (2.55e-1)" "unprognostic (2.97e-1)" "unprognostic (7.22e-2)" "unprognostic (5.59e-2)" "unprognostic (3.47e-2)" "unprognostic (1.01e-1)" "unprognostic (1.88e-1)" "unprognostic (1.73e-1)" "unprognostic (2.99e-1)" "unprognostic (3.14e-1)" "unprognostic (1.79e-3)" "unprognostic (2.78e-2)" "unprognostic (8.67e-2)" "potential prognostic favorable (5.88e-4)" CSKMT "CS-KMT, METTL12, U99HG" ENSG00000214756 "Citrate synthase lysine methyltransferase" A8MUP2 11 62665309-62668496 "Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 79.2;Colonocytes: 114.8;Hepatic stellate cells: 77.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" HPA038533 Approved NA Yes "Cluster 5: Non-specific - Cell proliferation" "Cluster 24: Non-specific - Unknown function" "Cluster 65: Non-specific - Cell growth & division" 6 "HPA038533: " "potential prognostic favorable (1.16e-6)" "unprognostic (2.28e-1)" "unprognostic (4.22e-2)" "unprognostic (8.08e-2)" "unprognostic (1.56e-1)" "unprognostic (1.14e-1)" CSMD1 "KIAA1890, PPP1R24" ENSG00000183117 "CUB and Sushi multiple domains 1" Q96PZ7 8 2935353-4994972 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 4.0;retina: 1.4;testis: 2.4" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 4078.4;Brain inhibitory neurons: 4301.0;Conjunctival goblet cells: 1040.8;Oligodendrocyte progenitor cells: 7057.9;Other brain neurons: 2052.0;Sertoli cells: 2669.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 1.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells, Skin - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA074707 Approved Vesicles NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 35: Neurons - Synaptic function & neurogenesis" 1 Vesicles "HPA074707: " "unprognostic (1.46e-1)" "unprognostic (1.03e-3)" "unprognostic (7.65e-2)" CSMD2 KIAA1884 ENSG00000121904 "CUB and Sushi multiple domains 2" Q7Z408 1 33513998-34165842 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.4;pancreas: 1.3" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 232.0;Brain inhibitory neurons: 263.3;Corticotrophs: 86.0;Early spermatids: 77.2;Oligodendrocyte progenitor cells: 543.9;Oligodendrocytes: 122.5;Other brain neurons: 353.9;Retinal amacrine cells: 95.5;Retinal bipolar cells: 126.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in single" "Glioblastoma Multiforme (TCGA): 3.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "Brain cancer: 3.9" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 109: Neurons - Neuronal signaling" 1 "unprognostic (1.22e-1)" "unprognostic (4.58e-1)" "unprognostic (3.08e-2)" "potential prognostic favorable (1.07e-5)" "unprognostic (1.19e-2)" "unprognostic (8.08e-2)" CSMD3 ENSG00000164796 "CUB and Sushi multiple domains 3" Q7Z407 8 112222928-113436939 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 2.6" "Group enriched" "Detected in many" 5 "Brain excitatory neurons: 1241.8;Brain inhibitory neurons: 1428.7;Ependymal cells: 1548.8;Oligodendrocyte progenitor cells: 2465.0;Other brain neurons: 1019.8" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enteroendocrine cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029007, HPA029008" Uncertain Approved "Plasma membrane" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 29: Forebrain - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" "Plasma membrane" "HPA029007: , HPA029008: " "unprognostic (3.96e-1)" "potential prognostic favorable (5.38e-5)" CSN1S1 "CASA, CSN1" ENSG00000126545 "Casein alpha s1" P47710 4 69931068-69946574 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Milk protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 86 "breast: 1289.8" "Cell type enriched" "Detected in some" 8235 "Breast lactating cells: 90951.8" "Cell type enriched" "Detected in some" 7 "hippocampal CA1-3: 31.5" "Group enriched" "Detected in some" 68 "Breast Invasive Carcinoma (TCGA): 21.9;Lung Squamous Cell Carcinoma (TCGA): 6.2" "Region enhanced" "Detected in single" "hypothalamus: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 16 "thyroid cancer: 12.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035659, HPA057031" Enhanced "Secreted in female reproductive system" Other NA NA "Cluster 55: Breast - Lactation" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 72: Neuronal - Signal transduction" "Cluster 4: Breast lactating luminal cells - Lactation" 4 "HPA035659: , HPA057031: " "unprognostic (9.08e-2)" "unprognostic (3.91e-1)" "unprognostic (2.08e-1)" CSN2 CASB ENSG00000135222 "Casein beta" P05814 4 69955256-69965728 "Predicted secreted proteins" "Milk protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 103 "breast: 538.2" "Cell type enriched" "Detected in some" 30016 "Breast lactating cells: 333043.0" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 203 "Breast Invasive Carcinoma (TCGA): 68.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Minor Salivary Gland - Minor salivary glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA041036 Supported "Secreted in female reproductive system" Other NA NA 120000 "Cluster 55: Breast - Lactation" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 4: Breast lactating luminal cells - Lactation" 7 "HPA041036: " "unprognostic (4.77e-1)" CSN3 CSN10 ENSG00000171209 "Casein kappa" P07498 4 70238382-70251474 "Predicted secreted proteins" "Milk protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "breast: 336.9" "Cell type enriched" "Detected in some" 147 "Breast lactating cells: 25926.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 14 "Breast Invasive Carcinoma (TCGA): 55.6;Lung Squamous Cell Carcinoma (TCGA): 24.4" "Region enhanced" "Detected in single" "midbrain: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "breast cancer: 3.6;colorectal cancer: 13.8;lung cancer: 4.8;thyroid cancer: 9.9" "Minor Salivary Gland - Minor salivary glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA035953, HPA035954" Enhanced "Secreted in female reproductive system" Other NA NA 9800 "Cluster 55: Breast - Lactation" "Cluster 46: Brainstem - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 4: Breast lactating luminal cells - Lactation" 8 "HPA035953: , HPA035954: " "unprognostic (4.25e-3)" "unprognostic (3.50e-1)" "unprognostic (7.76e-2)" "unprognostic (5.92e-2)" "unprognostic (1.29e-1)" "unprognostic (2.27e-2)" CSNK1A1 "CK1, CK1a, CK1alpha, CKIa, CKIalpha" ENSG00000113712 "Casein kinase 1 alpha 1" P48729 5 149492982-149551471 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016680, HPA051334" Uncertain Supported Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 127 Cytosol "CAB016680: , HPA051334: " "unprognostic (1.04e-1)" "potential prognostic unfavorable (8.62e-4)" "unprognostic (8.89e-2)" "unprognostic (7.90e-2)" "unprognostic (1.50e-2)" "unprognostic (1.66e-1)" "unprognostic (4.00e-2)" "unprognostic (3.07e-2)" "unprognostic (1.45e-1)" "potential prognostic unfavorable (3.07e-4)" "potential prognostic favorable (5.21e-4)" "unprognostic (5.40e-2)" "unprognostic (2.11e-2)" "unprognostic (4.42e-3)" "unprognostic (3.72e-2)" "unprognostic (1.90e-2)" "unprognostic (1.62e-1)" "unprognostic (2.32e-2)" "unprognostic (1.23e-1)" "unprognostic (2.14e-2)" "unprognostic (3.76e-3)" "potential prognostic unfavorable (6.44e-6)" "unprognostic (3.41e-3)" "unprognostic (7.68e-2)" "unprognostic (1.84e-1)" "unprognostic (2.49e-1)" "unprognostic (1.64e-1)" "unprognostic (3.06e-1)" "unprognostic (1.36e-1)" "unprognostic (7.52e-3)" "unprognostic (4.09e-1)" CSNK1A1L MGC33182 ENSG00000180138 "Casein kinase 1 alpha 1 like" Q8N752 13 37103259-37105664 "Enzymes, Predicted intracellular proteins" "Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "testis: 3.3" "Group enriched" "Detected in some" 17 "Early primary spermatocytes: 8.3;Early spermatids: 26.1;Late primary spermatocytes: 27.1;Late spermatids: 30.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 33 "neutrophil: 7.6" "Lineage enriched" "Detected in single" 39 "granulocytes: 7.6" "Not detected" "Not detected" "Lung - Neutrophils_2, Spleen - Neutrophils_2" HPA051334 Approved Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 57: Testis - Spermatogenesis" "Cluster 61: BICR 18 - Protein kinases" "Cluster 3: Early primary spermatocytes - Early meiosis" 7 Cytosol "HPA051334: " CSNK1D "CKID, CKIdelta, HCKID" ENSG00000141551 "Casein kinase 1 delta" P48730 17 82239023-82273700 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 371.3;Late spermatids: 1358.7;Neutrophils: 605.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015410, HPA070888, HPA072593" Approved Supported "Plasma membrane,Actin filaments,Primary cilium,Cytosol,Principal piece,End piece" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 24: Non-specific - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 80 "Plasma membrane, Cytosol" "Actin filaments, Primary cilium, Principal piece, End piece" "CAB015410: , HPA070888: , HPA072593: " "unprognostic (1.36e-1)" "unprognostic (6.98e-2)" "unprognostic (1.83e-1)" "unprognostic (9.43e-3)" "unprognostic (2.18e-2)" "unprognostic (6.54e-2)" "unprognostic (5.32e-2)" "unprognostic (7.78e-2)" "unprognostic (1.92e-2)" "unprognostic (1.13e-3)" "unprognostic (2.39e-2)" "unprognostic (7.58e-2)" "unprognostic (6.12e-2)" "validated prognostic unfavorable (1.10e-5)" "validated prognostic unfavorable (5.43e-4)" "unprognostic (1.11e-1)" "unprognostic (8.86e-2)" "unprognostic (6.25e-3)" "unprognostic (1.92e-2)" "unprognostic (1.60e-1)" "unprognostic (2.54e-1)" "unprognostic (1.31e-2)" "potential prognostic unfavorable (1.34e-5)" "unprognostic (1.17e-2)" "unprognostic (3.63e-2)" "unprognostic (2.96e-1)" "unprognostic (2.54e-1)" "unprognostic (1.16e-1)" "unprognostic (2.45e-1)" "unprognostic (3.37e-2)" "unprognostic (2.27e-1)" CSNK1E "CKIE, CKIepsilon, HCKIE" ENSG00000213923 "Casein kinase 1 epsilon" P49674 22 38290691-38318084 "Cancer-related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bergmann glia: 117.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 14.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009626, HPA026288" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 2: Non-specific - Mixed function" "Cluster 34: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 22: Non-specific - Basic cellular functions" 108 "Nucleoplasm, Cytosol" "CAB009626: , HPA026288: " "unprognostic (7.95e-2)" "unprognostic (1.73e-1)" "unprognostic (1.86e-1)" "unprognostic (2.51e-3)" "unprognostic (4.05e-1)" "unprognostic (2.31e-1)" "unprognostic (1.19e-2)" "unprognostic (2.90e-3)" "unprognostic (3.64e-2)" "unprognostic (2.07e-1)" "unprognostic (9.27e-3)" "unprognostic (1.96e-2)" "unprognostic (4.95e-2)" "potential prognostic unfavorable (1.42e-7)" "unprognostic (7.18e-2)" "unprognostic (2.26e-3)" "unprognostic (4.66e-3)" "unprognostic (1.18e-1)" "unprognostic (1.56e-3)" "unprognostic (8.45e-2)" "unprognostic (2.56e-1)" "unprognostic (7.61e-2)" "unprognostic (3.01e-3)" "unprognostic (3.20e-1)" "unprognostic (1.41e-2)" "unprognostic (1.60e-2)" "unprognostic (2.24e-1)" "unprognostic (2.22e-1)" "unprognostic (4.82e-2)" "unprognostic (2.38e-2)" "unprognostic (5.18e-2)" CSNK1G1 CK1gamma1 ENSG00000169118 "Casein kinase 1 gamma 1" Q9HCP0 15 64165525-64356173 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 33.3" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 104.0;Early spermatids: 122.5;Ependymal cells: 115.4;Late spermatids: 286.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018209 Supported Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 47: Testis - Mixed function" "Cluster 29: Forebrain - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 22: Non-specific - Basic cellular functions" 8 Cytosol "HPA018209: " "unprognostic (1.46e-2)" "unprognostic (4.09e-2)" "unprognostic (9.58e-2)" "unprognostic (2.82e-1)" "unprognostic (2.79e-1)" "unprognostic (1.21e-1)" "unprognostic (1.57e-1)" "unprognostic (5.58e-2)" "unprognostic (8.41e-2)" "potential prognostic unfavorable (1.51e-5)" "potential prognostic favorable (2.52e-4)" "unprognostic (3.14e-3)" "unprognostic (9.91e-2)" "unprognostic (3.57e-3)" "unprognostic (2.93e-3)" "unprognostic (3.75e-2)" "unprognostic (4.29e-2)" "unprognostic (2.31e-1)" "unprognostic (4.31e-3)" "unprognostic (8.09e-2)" "unprognostic (1.58e-1)" "unprognostic (3.41e-1)" "unprognostic (1.78e-3)" "unprognostic (2.00e-1)" "unprognostic (3.48e-2)" "unprognostic (5.06e-3)" "unprognostic (2.23e-2)" "unprognostic (5.31e-2)" "unprognostic (2.86e-2)" "unprognostic (2.08e-2)" "unprognostic (1.68e-1)" CSNK1G2 CK1g2 ENSG00000133275 "Casein kinase 1 gamma 2" P78368 19 1941172-1981338 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 333.1;Late spermatids: 1151.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen), Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034868, HPA056572" Uncertain Approved Vesicles,Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 67: Testis - Mixed function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 31 Vesicles Cytosol "HPA034868: , HPA056572: " "unprognostic (1.30e-2)" "unprognostic (4.24e-2)" "unprognostic (1.44e-3)" "unprognostic (9.13e-2)" "unprognostic (2.32e-3)" "unprognostic (4.65e-3)" "unprognostic (1.92e-1)" "unprognostic (6.51e-2)" "unprognostic (7.19e-3)" "unprognostic (1.49e-2)" "unprognostic (1.15e-2)" "unprognostic (1.61e-1)" "unprognostic (1.91e-1)" "unprognostic (6.03e-3)" "unprognostic (3.06e-2)" "unprognostic (1.43e-1)" "unprognostic (4.48e-2)" "unprognostic (3.57e-1)" "unprognostic (7.42e-2)" "unprognostic (8.90e-2)" "unprognostic (3.87e-2)" "unprognostic (1.22e-1)" "unprognostic (1.09e-1)" "unprognostic (1.08e-2)" "unprognostic (1.02e-2)" "potential prognostic favorable (8.98e-5)" "unprognostic (7.22e-2)" "unprognostic (4.44e-2)" "unprognostic (1.93e-1)" "unprognostic (1.69e-1)" "unprognostic (6.82e-2)" CSNK1G3 ENSG00000151292 "Casein kinase 1 gamma 3" Q9Y6M4 5 123512177-123617049 "Enzymes, Predicted intracellular proteins" "Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027010 Approved NA NA "Cluster 32: Basophils - Transcription" "Cluster 77: Intestine - Digestion" "Cluster 31: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 17 "HPA027010: " "unprognostic (3.83e-2)" "unprognostic (1.12e-1)" "unprognostic (1.46e-2)" "unprognostic (3.38e-2)" "unprognostic (3.61e-2)" "unprognostic (2.80e-2)" "unprognostic (3.17e-1)" "unprognostic (8.79e-2)" "unprognostic (1.86e-1)" "potential prognostic unfavorable (6.47e-4)" "potential prognostic favorable (4.92e-6)" "unprognostic (2.46e-2)" "unprognostic (6.54e-2)" "unprognostic (5.17e-3)" "unprognostic (1.84e-1)" "unprognostic (1.30e-1)" "unprognostic (5.83e-2)" "unprognostic (4.74e-2)" "unprognostic (1.12e-1)" "unprognostic (2.70e-3)" "potential prognostic unfavorable (2.78e-4)" "unprognostic (2.35e-3)" "unprognostic (1.07e-1)" "unprognostic (1.18e-1)" "unprognostic (1.73e-3)" "unprognostic (1.05e-1)" "unprognostic (9.05e-2)" "unprognostic (1.83e-1)" "unprognostic (4.20e-1)" "unprognostic (1.57e-2)" "unprognostic (3.05e-1)" CSNK2A1 "Cka1, Cka2" ENSG00000101266 "Casein kinase 2 alpha 1" P68400 20 472498-543835 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Biological rhythms, Cell cycle, Transcription, Transcription regulation, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "CAB020680, HPA059206, HPA061698, CAB069395" Supported Supported "Nucleoplasm,Primary cilium" NA NA 510000 "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 17: Non-specific - RNA processing" 621 Nucleoplasm "Primary cilium" "CAB020680: , CAB069395: , HPA059206: , HPA061698: " "unprognostic (3.45e-1)" "unprognostic (3.30e-2)" "unprognostic (2.18e-1)" "unprognostic (5.53e-2)" "unprognostic (6.59e-2)" "unprognostic (6.17e-2)" "unprognostic (1.91e-1)" "unprognostic (1.59e-2)" "unprognostic (5.51e-2)" "unprognostic (3.86e-2)" "unprognostic (2.22e-3)" "unprognostic (5.17e-2)" "unprognostic (2.37e-1)" "validated prognostic unfavorable (7.59e-6)" "validated prognostic unfavorable (8.14e-5)" "unprognostic (1.72e-2)" "unprognostic (7.02e-2)" "unprognostic (3.48e-2)" "unprognostic (2.68e-1)" "unprognostic (3.28e-1)" "unprognostic (2.59e-1)" "potential prognostic unfavorable (6.69e-4)" "unprognostic (9.30e-3)" "unprognostic (1.33e-1)" "unprognostic (2.16e-2)" "unprognostic (2.15e-1)" "unprognostic (5.01e-1)" "unprognostic (1.83e-1)" "unprognostic (7.46e-2)" "unprognostic (2.10e-2)" "unprognostic (1.48e-1)" CSNK2A2 "CK2alpha', CSNK2A1" ENSG00000070770 "Casein kinase 2 alpha 2" P19784 16 58157907-58198106 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Transcription, Transcription regulation, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 113.9" "Cell type enhanced" "Detected in all" "Early spermatids: 289.1;Late spermatids: 404.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Skin - Keratinocyte (granular), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 110000 "Cluster 41: Basophils - Unknown function" "Cluster 47: Testis - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 467 "unprognostic (1.82e-2)" "unprognostic (1.73e-2)" "unprognostic (1.12e-1)" "unprognostic (2.78e-1)" "unprognostic (1.07e-1)" "unprognostic (1.06e-1)" "unprognostic (5.39e-2)" "unprognostic (1.94e-1)" "potential prognostic unfavorable (3.91e-5)" "unprognostic (9.96e-2)" "unprognostic (5.27e-2)" "unprognostic (3.31e-2)" "unprognostic (5.07e-3)" "potential prognostic unfavorable (3.10e-5)" "unprognostic (6.62e-3)" "unprognostic (1.52e-1)" "unprognostic (3.11e-2)" "unprognostic (2.88e-1)" "unprognostic (1.40e-1)" "unprognostic (7.08e-2)" "unprognostic (8.82e-2)" "unprognostic (1.61e-1)" "unprognostic (1.15e-2)" "unprognostic (3.33e-1)" "unprognostic (1.48e-1)" "unprognostic (3.22e-1)" "unprognostic (4.98e-2)" "unprognostic (3.24e-2)" "unprognostic (1.55e-1)" "unprognostic (4.98e-1)" "unprognostic (1.47e-2)" CSNK2A3 CSNK2A1P ENSG00000254598 "Casein kinase 2 alpha 3" Q8NEV1 11 11351942-11353250 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "skeletal muscle: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "HPA059206, HPA061698" Uncertain Approved "Nucleoplasm,Primary cilium" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 29: Forebrain - Mixed function" "Cluster 61: BICR 18 - Protein kinases" 3 Nucleoplasm "Primary cilium" "HPA059206: , HPA061698: " "unprognostic (4.11e-3)" CSNK2B "Ckb1, Ckb2" ENSG00000204435 "Casein kinase 2 beta" P67870 6 31665227-31670343 "Cancer-related genes, Disease related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Wnt signaling pathway" "Cancer-related genes, Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 331.2;Esophageal apical cells: 306.2;Gastric progenitor cells: 289.7;Late primary spermatocytes: 720.3;Oocytes: 308.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 429.0" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004349, HPA005944, CAB013087, CAB016059, HPA070343" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Perinuclear theca,Calyx,Mid piece" NA NA 71000 "Cluster 32: Basophils - Transcription" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 15: Non-specific - Protein processing" 399 Nucleoplasm "Nucleoli fibrillar center, Perinuclear theca, Calyx, Mid piece" "CAB004349: , CAB013087: , CAB016059: , HPA005944: , HPA070343: " "unprognostic (2.00e-1)" "unprognostic (1.76e-1)" "unprognostic (5.95e-2)" "unprognostic (5.60e-2)" "unprognostic (1.08e-1)" "unprognostic (6.33e-3)" "unprognostic (1.95e-1)" "unprognostic (3.57e-2)" "unprognostic (2.26e-1)" "unprognostic (2.14e-2)" "unprognostic (2.33e-2)" "unprognostic (9.86e-2)" "unprognostic (2.13e-1)" "unprognostic (3.09e-3)" "potential prognostic unfavorable (2.71e-4)" "unprognostic (9.82e-2)" "unprognostic (1.23e-1)" "unprognostic (1.16e-1)" "unprognostic (3.74e-2)" "unprognostic (1.07e-1)" "unprognostic (1.37e-1)" "unprognostic (2.14e-1)" "unprognostic (4.10e-2)" "unprognostic (4.10e-1)" "unprognostic (2.37e-1)" "unprognostic (1.92e-2)" "unprognostic (2.16e-1)" "unprognostic (6.66e-2)" "unprognostic (3.25e-1)" "unprognostic (1.86e-1)" "unprognostic (2.84e-1)" CSNKA2IP ENSG00000283434 "Casein kinase 2 subunit alpha' interacting protein" A0A1B0GTH6 3 88338416-88467594 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 219 "testis: 21.9" "Cell type enhanced" "Detected in some" "Early spermatids: 163.2;Late primary spermatocytes: 99.5;Late spermatids: 414.9" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" CSPG4 "CSPG4A, HMW-MAA, MCSP, MCSPG, MEL-CSPG, MSK16, NG2" ENSG00000173546 "Chondroitin sulfate proteoglycan 4" Q6UVK1 15 75674322-75712848 "Predicted membrane proteins" "Angiogenesis, Differentiation, Tissue remodeling" "Developmental protein, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 124.5" "Cell type enhanced" "Detected in some" "Adipocytes: 52.3;Epicardial cells: 38.7;Melanocytes: 39.2;Oligodendrocyte progenitor cells: 101.9;Pericytes: 68.1;Salivary myoepithelial cells: 22.0;Schwann cells: 54.1;Smooth muscle cells: 63.8;Thymic myoid cells: 78.9;Vascular smooth muscle cells: 129.4" "Group enriched" "Detected in some" 5 "oligodendrocyte precursor cell: 111.5;pericyte: 105.3;vascular associated smooth muscle cell: 115.7" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 124.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 73.0" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Lung - Smooth muscle cells, Minor Salivary Gland - Endothelial cells, Prostate - Smooth muscle cells, Spleen - Fibroblasts_2, Testis - Endothelial cells, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001933, HPA002951, CAB016189, HPA042785, HPA050008" Approved Approved "Plasma membrane" NA NA 29000000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 69: Skin cancer - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 30 "Plasma membrane" "CAB016189: , HPA001933: , HPA002951: , HPA042785: , HPA050008: " "unprognostic (2.60e-1)" "unprognostic (7.39e-3)" "unprognostic (2.96e-1)" "unprognostic (1.99e-2)" "unprognostic (2.15e-1)" "unprognostic (6.36e-2)" "unprognostic (6.93e-2)" "unprognostic (1.03e-1)" "unprognostic (3.89e-1)" "unprognostic (4.21e-2)" "validated prognostic favorable (2.38e-4)" "validated prognostic favorable (4.69e-4)" "potential prognostic unfavorable (9.29e-5)" "unprognostic (1.70e-2)" "unprognostic (2.34e-1)" "unprognostic (3.30e-2)" "potential prognostic unfavorable (9.38e-4)" "unprognostic (4.91e-2)" "unprognostic (1.55e-1)" "unprognostic (1.55e-2)" "unprognostic (2.77e-1)" "unprognostic (4.05e-2)" "unprognostic (8.16e-2)" "unprognostic (2.02e-1)" "unprognostic (1.93e-2)" "unprognostic (1.92e-2)" "unprognostic (1.78e-1)" "unprognostic (2.59e-2)" "unprognostic (1.07e-2)" "unprognostic (2.03e-2)" "unprognostic (7.84e-2)" CSPG5 NGC ENSG00000114646 "Chondroitin sulfate proteoglycan 5" O95196 3 47562238-47580792 "Predicted membrane proteins, Predicted secreted proteins" "Differentiation, Growth regulation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 20 "brain: 103.3;choroid plexus: 53.4;retina: 26.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 53.6;Astrocytes: 83.5;Choroid plexus epithelial cells: 49.0;Müller glia: 107.8;Oligodendrocyte progenitor cells: 318.5;Other brain neurons: 39.3;Respiratory ionocytes: 55.9;Retinal pigment epithelial cells: 225.9" "Cell type enriched" "Detected in all" 5 "oligodendrocyte precursor cell: 315.1" "Cancer enriched" "Detected in many" 18 "Glioblastoma Multiforme (TCGA): 165.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 14.1" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA071779, HPA076601" Enhanced Approved "Golgi apparatus,Vesicles,Plasma membrane,Cytosol" "Secreted in brain" "Developmental protein" NA No "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 5 "Golgi apparatus, Vesicles, Plasma membrane, Cytosol" "HPA071779: , HPA076601: " "unprognostic (3.91e-2)" "unprognostic (2.85e-1)" "unprognostic (1.45e-1)" "unprognostic (2.16e-1)" "unprognostic (1.98e-1)" "unprognostic (1.48e-2)" "unprognostic (2.66e-2)" "unprognostic (2.73e-3)" "unprognostic (4.17e-1)" "unprognostic (1.42e-1)" "unprognostic (5.18e-2)" "unprognostic (3.88e-2)" "potential prognostic favorable (3.58e-5)" "unprognostic (6.28e-2)" "unprognostic (6.57e-2)" "unprognostic (2.91e-1)" "unprognostic (2.69e-1)" "unprognostic (1.03e-1)" "unprognostic (1.48e-2)" CSPP1 "CSPP, CSPP-L, FLJ22490, JBTS21" ENSG00000104218 "Centrosome and spindle pole associated protein 1" Q1MSJ5 8 67062417-67196778 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Joubert syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 518.7;Endometrial ciliated cells: 826.4;Ependymal cells: 801.5;Epididymal efferent duct ciliated cells: 515.0;Fallopian tube ciliated cells: 489.4;Podocytes: 559.6;Respiratory ciliated cells: 563.4;Sertoli cells: 493.3" "Cell type enhanced" "Detected in all" "ependymal cell: 878.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056174 Approved "Vesicles,Primary cilium,Centriolar satellite,Centrosome,Basal body" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 34: Ciliated cells - Cilia assembly & function" 10 "Centriolar satellite, Centrosome, Basal body" "Vesicles, Primary cilium" "HPA056174: " "unprognostic (8.41e-3)" "unprognostic (4.30e-3)" "unprognostic (3.84e-1)" "unprognostic (8.47e-2)" "unprognostic (1.16e-1)" "unprognostic (2.33e-1)" "unprognostic (2.70e-1)" "unprognostic (3.46e-1)" "unprognostic (2.70e-2)" "unprognostic (8.90e-2)" "potential prognostic favorable (1.51e-6)" "unprognostic (9.06e-2)" "unprognostic (2.22e-1)" "unprognostic (3.53e-1)" "unprognostic (1.17e-1)" "unprognostic (2.75e-2)" "unprognostic (2.87e-2)" "unprognostic (1.25e-2)" "unprognostic (6.70e-2)" "unprognostic (9.31e-2)" "unprognostic (1.34e-2)" "unprognostic (1.36e-2)" "unprognostic (3.59e-2)" "potential prognostic favorable (3.56e-4)" "unprognostic (1.21e-1)" "unprognostic (1.58e-1)" "unprognostic (1.24e-1)" "unprognostic (2.64e-1)" "unprognostic (2.58e-2)" "unprognostic (2.76e-3)" CSRNP1 "AXUD1, DKFZp566F164, FAM130B, TAIP-3, URAX1" ENSG00000144655 "Cysteine and serine rich nuclear protein 1" Q96S65 3 39141855-39154562 "Predicted intracellular proteins, Transcription factors" "Apoptosis, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 182.4" "Cell type enhanced" "Detected in many" "Breast secretory cells: 202.3;Endometrial glandular cells: 210.8;Endometrial luminal cells: 240.2;Epididymal basal cells: 234.7;Neutrophils: 382.3" "Cell type enhanced" "Detected in all" "endothelial cell: 25.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 17.2" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045207, HPA058463" Supported Nucleoplasm,Vesicles NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 15: Bone marrow - Innate immune response" "Cluster 44: Non-specific - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 17 Nucleoplasm Vesicles "HPA045207: , HPA058463: " "unprognostic (5.31e-2)" "unprognostic (1.01e-1)" "unprognostic (3.47e-2)" "unprognostic (7.03e-2)" "unprognostic (9.06e-2)" "unprognostic (1.41e-2)" "unprognostic (4.46e-1)" "unprognostic (1.55e-1)" "unprognostic (1.95e-1)" "unprognostic (9.94e-2)" "validated prognostic favorable (4.36e-7)" "validated prognostic favorable (1.16e-4)" "unprognostic (1.69e-2)" "unprognostic (6.71e-2)" "unprognostic (7.77e-3)" "unprognostic (2.77e-1)" "unprognostic (3.04e-1)" "unprognostic (2.84e-3)" "unprognostic (3.47e-1)" "unprognostic (2.68e-2)" "unprognostic (2.11e-2)" "unprognostic (3.25e-1)" "unprognostic (9.09e-2)" "unprognostic (2.51e-1)" "unprognostic (3.44e-1)" "unprognostic (1.53e-3)" "unprognostic (6.64e-2)" "potential prognostic unfavorable (4.30e-4)" "unprognostic (8.40e-2)" "unprognostic (8.60e-2)" "unprognostic (4.42e-1)" CSRNP2 "C12ORF2, C12orf22, FAM130A1, PPP1R72, TAIP-12" ENSG00000110925 "Cysteine and serine rich nuclear protein 2" Q9H175 12 51061205-51083664 "Predicted intracellular proteins, Transcription factors" "Apoptosis, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 105.5;Tuft cells: 138.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018503, HPA019914" Approved Approved "Nuclear speckles" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 38: Non-specific - Transcription" "Cluster 65: Non-specific - Cell growth & division" 7 "Nuclear speckles" "HPA018503: , HPA019914: " "unprognostic (5.27e-2)" "unprognostic (2.00e-3)" "unprognostic (3.04e-2)" "unprognostic (4.27e-2)" "unprognostic (3.84e-1)" "unprognostic (7.12e-2)" "unprognostic (3.58e-1)" "unprognostic (3.60e-1)" "unprognostic (9.74e-2)" "unprognostic (3.16e-2)" "unprognostic (1.38e-1)" "unprognostic (5.34e-3)" "unprognostic (1.14e-1)" "unprognostic (1.41e-3)" "unprognostic (6.39e-2)" "unprognostic (2.10e-1)" "unprognostic (2.90e-1)" "unprognostic (9.19e-3)" "unprognostic (1.79e-1)" "unprognostic (4.37e-1)" "unprognostic (6.45e-3)" "unprognostic (1.73e-1)" "unprognostic (1.16e-3)" "unprognostic (4.84e-2)" "unprognostic (3.09e-1)" "unprognostic (4.94e-2)" "unprognostic (1.99e-2)" "unprognostic (7.90e-2)" "unprognostic (2.26e-1)" "unprognostic (1.84e-1)" "unprognostic (2.15e-1)" CSRNP3 "FAM130A2, FLJ32093, PPP1R73, TAIP-2" ENSG00000178662 "Cysteine and serine rich nuclear protein 3" Q8WYN3 2 165469647-165689407 "Predicted intracellular proteins, Transcription factors" "Apoptosis, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 9.3" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 333.3;Brain inhibitory neurons: 457.8;Choroid plexus epithelial cells: 861.8;Cone photoreceptor cells: 310.5;Corticotrophs: 650.5;Lacrimal acinar cells: 394.0;Lactotrophs: 534.2;Oligodendrocyte progenitor cells: 424.8;Other brain neurons: 354.1;Retinal pigment epithelial cells: 379.4;Somatotrophs: 328.8;Thyrotrophs: 517.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 6.4" "Liver - Hepatocytes, Minor Salivary Gland - Minor salivary gland ductal cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017905 Approved Approved "Nucleoplasm,Nucleoli rim" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" "Nucleoli rim" Nucleoplasm "HPA017905: " "unprognostic (3.72e-1)" "unprognostic (9.23e-2)" "unprognostic (5.67e-2)" "unprognostic (1.83e-1)" "unprognostic (3.10e-2)" "unprognostic (9.61e-3)" "unprognostic (9.33e-2)" "unprognostic (7.12e-2)" "unprognostic (1.15e-1)" "unprognostic (2.38e-1)" "unprognostic (2.29e-1)" CSRP1 "CSRP, CYRP, D1S181E" ENSG00000159176 "Cysteine and glycine rich protein 1" P21291 1 201483530-201509456 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 2631.0;intestine: 2839.1" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 2138.1;Decidual stromal cells: 453.1;Extravillous trophoblasts: 514.1;Hepatic stellate cells: 438.9;Megakaryocytes: 544.0;Smooth muscle cells: 2898.2;Vascular smooth muscle cells: 884.2" "Group enriched" "Detected in all" 4 "astrocyte: 186.7;Bergmann glia: 196.3;committed oligodendrocyte precursor: 73.3;oligodendrocyte: 252.4;vascular associated smooth muscle cell: 291.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Breast - Breast myoepithelial cells, Colon - Smooth muscle cells, Kidney - Fibroblasts, Minor Salivary Gland - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045617 Uncertain NA NA 11000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 19: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 6 "HPA045617: " "unprognostic (1.00e-2)" "unprognostic (2.42e-1)" "unprognostic (2.95e-1)" "unprognostic (6.58e-3)" "unprognostic (6.60e-2)" "unprognostic (2.07e-1)" "unprognostic (1.22e-1)" "unprognostic (1.49e-2)" "potential prognostic unfavorable (7.89e-4)" "unprognostic (5.83e-3)" "unprognostic (8.60e-3)" "unprognostic (1.66e-2)" "unprognostic (2.09e-2)" "unprognostic (1.43e-1)" "potential prognostic favorable (6.40e-4)" "unprognostic (1.86e-1)" "unprognostic (2.24e-1)" "unprognostic (4.37e-3)" "unprognostic (1.59e-2)" "unprognostic (3.18e-1)" "unprognostic (4.16e-3)" "unprognostic (2.13e-2)" "unprognostic (5.34e-2)" "unprognostic (8.68e-3)" "unprognostic (2.66e-2)" "unprognostic (2.00e-1)" "unprognostic (2.95e-1)" "unprognostic (1.26e-2)" "unprognostic (1.82e-1)" "unprognostic (1.40e-1)" "potential prognostic favorable (4.20e-4)" CSRP2 "CRP2, LMO5, SmLIM" ENSG00000175183 "Cysteine and glycine rich protein 2" Q16527 12 76858709-76879023 "Predicted intracellular proteins" Differentiation "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 333.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 331.4;Esophageal basal cells: 354.9;Esophageal suprabasal cells: 280.1;Fallopian tube ciliated cells: 189.3;Migrating cytotrophoblasts: 217.1;Müller glia: 381.7;Ocular epithelial cells: 1187.0;Pericytes: 219.8;Vascular smooth muscle cells: 542.1" "Group enriched" "Detected in many" 6 "endothelial cell: 119.8;ependymal cell: 85.9;pericyte: 156.9;vascular associated smooth muscle cell: 131.9" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 287.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Colon - Endothelial cells, Spleen - Fibroblasts_1, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045617 Uncertain NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 46: Brainstem - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 100: Stratified epithelial cells - Barrier functions" 5 "HPA045617: " "unprognostic (1.49e-1)" "unprognostic (6.04e-2)" "unprognostic (3.70e-1)" "unprognostic (2.62e-1)" "unprognostic (1.91e-2)" "unprognostic (1.10e-2)" "unprognostic (3.08e-1)" "unprognostic (2.18e-2)" "unprognostic (4.45e-3)" "unprognostic (6.43e-2)" "unprognostic (2.90e-2)" "unprognostic (3.36e-2)" "unprognostic (2.85e-3)" "unprognostic (1.55e-1)" "unprognostic (1.78e-1)" "unprognostic (2.71e-2)" "unprognostic (5.69e-2)" "unprognostic (9.40e-2)" "unprognostic (2.28e-1)" "unprognostic (7.09e-2)" "unprognostic (8.39e-2)" "unprognostic (2.68e-1)" "unprognostic (1.06e-1)" "unprognostic (4.93e-3)" "unprognostic (7.52e-2)" "unprognostic (1.08e-1)" "unprognostic (1.79e-1)" "unprognostic (1.56e-2)" "unprognostic (2.61e-1)" "unprognostic (1.21e-1)" "unprognostic (4.29e-2)" CSRP3 "CLP, CMD1M, MLP" ENSG00000129170 "Cysteine and glycine rich protein 3" P50461 11 19182030-19210571 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Myogenesis, Transcription, Transcription regulation" "Actin-binding, Developmental protein" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 2447.5;skeletal muscle: 1545.8;tongue: 540.3" "Group enriched" "Detected in some" 9 "Cardiomyocytes: 327.8;Myonuclei: 238.0;Thymic myoid cells: 110.1" "Cell type enhanced" "Detected in single" "hippocampal CA4: 1.1" "Cancer enriched" "Detected in some" 7 "Head and Neck Squamous Cell Carcinoma (TCGA): 38.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Sarcoma: 1.3" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA042581 Enhanced Uncertain Nucleoplasm,Cytosol NA NA 130000 "Cluster 41: Striated muscle - Muscle contraction" "Cluster 9: Non-specific - Receptor signaling" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 55: Myocytes - Oxidative muscle function" 7 Cytosol Nucleoplasm "HPA042581: " "unprognostic (1.40e-2)" "unprognostic (1.36e-1)" CST1 ENSG00000170373 "Cystatin SN" P01037 20 23747562-23751268 "Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 119 "salivary gland: 26681.9" "Group enriched" "Detected in some" 42 "Lacrimal acinar cells: 898.6;Salivary acinar cells: 2358.9" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "pons: 2.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 91.6;liver cancer: 120.5" "Skin - Hair cortex cells, Skin - Inner root sheath cells" "CAB026769, HPA043706, HPA044763" Enhanced "Secreted to digestive system" "Enzyme inhibitor" NA NA 3300000 "Cluster 82: Salivary gland - Secretion" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 70: DU4475 - Unknown function" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 29 "CAB026769: , HPA043706: , HPA044763: " "potential prognostic favorable (3.08e-4)" "potential prognostic favorable (7.61e-4)" "unprognostic (1.04e-1)" "unprognostic (3.68e-2)" "unprognostic (1.62e-1)" "unprognostic (3.40e-1)" "unprognostic (1.12e-1)" "unprognostic (3.38e-1)" "unprognostic (1.27e-1)" "unprognostic (2.35e-1)" "unprognostic (9.15e-2)" "unprognostic (1.76e-2)" "unprognostic (3.02e-2)" "unprognostic (1.26e-1)" "unprognostic (8.11e-2)" "unprognostic (1.41e-3)" "unprognostic (2.00e-2)" "unprognostic (1.93e-2)" "unprognostic (2.12e-1)" "unprognostic (2.75e-1)" "unprognostic (2.24e-1)" "unprognostic (3.07e-1)" "unprognostic (1.34e-1)" "unprognostic (3.76e-1)" "unprognostic (6.11e-2)" "unprognostic (2.52e-1)" CST11 "CST8L, CTES2, dJ322G13.6" ENSG00000125831 "Cystatin 11" Q9H112 20 23450403-23452876 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Protease inhibitor, Thiol protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 478 "epididymis: 198.7" "Cell type enriched" "Detected in some" 21 "Epididymal principal cells: 1140.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA053399 Enhanced "Secreted in male reproductive system" "Enzyme inhibitor" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 50: Lymphoma - Unknown function" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 41 "HPA053399: " CST2 ENSG00000170369 "Cystatin SA" P09228 20 23823769-23826729 "Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 635 "salivary gland: 5624.3" "Cell type enriched" "Detected in some" 14 "Salivary acinar cells: 1054.6" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 50.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 9.5" "CAB024963, HPA043706, HPA044763" Enhanced "Secreted to digestive system" "Enzyme inhibitor" NA NA 450000 "Cluster 82: Salivary gland - Secretion" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 12 "CAB024963: , HPA043706: , HPA044763: " "unprognostic (2.77e-1)" "unprognostic (1.04e-2)" "unprognostic (2.33e-1)" "unprognostic (1.38e-3)" "unprognostic (3.59e-3)" "potential prognostic unfavorable (4.84e-5)" "unprognostic (4.16e-2)" "potential prognostic unfavorable (8.28e-5)" "unprognostic (4.00e-3)" "unprognostic (1.74e-1)" "unprognostic (1.40e-1)" "unprognostic (1.59e-1)" "unprognostic (1.24e-2)" "unprognostic (1.23e-1)" "unprognostic (7.07e-3)" "potential prognostic unfavorable (8.09e-5)" "unprognostic (1.42e-2)" "unprognostic (7.09e-2)" "unprognostic (3.71e-1)" "unprognostic (5.01e-2)" "unprognostic (8.45e-2)" "unprognostic (1.37e-1)" "potential prognostic unfavorable (5.71e-4)" "unprognostic (2.78e-1)" "unprognostic (4.46e-1)" "unprognostic (1.03e-1)" CST3 ENSG00000101439 "Cystatin C" P01034 20 23626706-23638473 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Age-related macular degeneration, Amyloidosis, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 4698.8;choroid plexus: 3897.4" "Cell type enhanced" "Detected in all" "cDC: 11109.8;Decidual stromal cells: 7914.1;Enterocytes: 3917.2;Epididymal efferent duct absorptive cells: 7351.5;Esophageal apical cells: 5195.9;Kupffer cells: 4972.9;Retinal pigment epithelial cells: 11782.8" "Cell type enhanced" "Detected in all" "astrocyte: 982.6;ependymal cell: 629.2" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 3923.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "classical monocyte: 4979.2;intermediate monocyte: 6434.2;myeloid DC: 7977.6;non-classical monocyte: 4321.2;plasmacytoid DC: 4438.0" "Group enriched" "Detected in all" 9 "dendritic cells: 7977.6;monocytes: 6434.2" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Skin - Fibroblasts_2, Spleen - Macrophages, Testis - Sertoli cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000118, HPA013143" Enhanced Supported "Golgi apparatus,Vesicles" "Secreted to blood" "Enzyme inhibitor" NA NA 1040000000 1300000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 39: Astrocytes - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 82: Dendritic cells - Antigen presentation" 14 "Golgi apparatus, Vesicles" "CAB000118: , HPA013143: " "unprognostic (1.20e-1)" "unprognostic (9.67e-2)" "unprognostic (4.59e-1)" "unprognostic (3.68e-3)" "unprognostic (9.31e-2)" "unprognostic (3.66e-2)" "unprognostic (2.41e-2)" "unprognostic (1.17e-2)" "unprognostic (2.87e-2)" "unprognostic (1.87e-1)" "unprognostic (1.26e-2)" "unprognostic (8.08e-3)" "potential prognostic favorable (2.37e-4)" "unprognostic (2.64e-2)" "potential prognostic favorable (3.45e-4)" "unprognostic (6.65e-3)" "unprognostic (3.56e-1)" "potential prognostic unfavorable (2.07e-4)" "unprognostic (2.79e-2)" "unprognostic (2.14e-1)" "unprognostic (1.18e-1)" "unprognostic (9.27e-3)" "unprognostic (1.44e-3)" "unprognostic (7.38e-2)" "unprognostic (5.28e-2)" "unprognostic (1.29e-1)" "unprognostic (1.53e-1)" "unprognostic (5.54e-2)" "unprognostic (3.04e-1)" "unprognostic (2.50e-1)" "unprognostic (5.15e-2)" CST4 ENSG00000101441 "Cystatin S" P01036 20 23685640-23689038 "Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 514 "salivary gland: 27276.5" "Cell type enriched" "Detected in some" 64 "Salivary acinar cells: 4304.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 17.0;Uterine Corpus Endometrial Carcinoma (TCGA): 23.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "breast cancer: 24.1;liver cancer: 45.0" "Prostate - Prostate glandular cells" "HPA043706, HPA044763" Supported "Secreted to digestive system" "Enzyme inhibitor" NA NA 2200000 "Cluster 82: Salivary gland - Secretion" "Cluster 27: Breast cancer - Unknown function" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 20 "HPA043706: , HPA044763: " "unprognostic (1.39e-1)" "unprognostic (2.50e-1)" "unprognostic (2.93e-1)" "unprognostic (4.25e-1)" "unprognostic (9.76e-2)" "unprognostic (2.99e-2)" "unprognostic (1.60e-1)" "potential prognostic unfavorable (1.08e-5)" "unprognostic (4.45e-3)" "unprognostic (6.71e-2)" "unprognostic (1.29e-1)" "unprognostic (2.69e-1)" "unprognostic (4.12e-2)" "unprognostic (3.90e-1)" "unprognostic (7.00e-2)" "unprognostic (4.19e-1)" CST5 ENSG00000170367 "Cystatin D" P28325 20 23875934-23879748 "Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 956 "salivary gland: 2025.9" "Cell type enriched" "Detected in some" 6 "Salivary acinar cells: 462.1" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 9 "Breast Invasive Carcinoma (TCGA): 36.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 2.0;colorectal cancer: 3.0;Esophageal cancer: 2.2" "Prostate - Smooth muscle cells" "CAB024944, HPA061449" Enhanced "Secreted to digestive system" "Enzyme inhibitor" NA NA "Cluster 82: Salivary gland - Secretion" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 15 "CAB024944: , HPA061449: " "unprognostic (8.14e-2)" "unprognostic (1.88e-1)" "unprognostic (4.27e-1)" "unprognostic (1.34e-1)" "unprognostic (1.17e-1)" "unprognostic (7.05e-3)" "unprognostic (2.36e-3)" "unprognostic (3.96e-2)" "unprognostic (1.05e-1)" "unprognostic (7.94e-2)" CST6 ENSG00000175315 "Cystatin E/M" Q15828 11 66012008-66013505 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 21 "skin 1: 1026.8" "Cell type enriched" "Detected in many" 4 "Esophageal apical cells: 1345.6" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 1.6;upper rhombic lip: 1.3" "Group enriched" "Detected in many" 5 "Bladder Urothelial Carcinoma (TCGA): 125.2;Thyroid Carcinoma (TCGA): 419.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 203.3;Bladder cancer: 187.9;pancreatic cancer: 182.1" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB019316, HPA044963" Enhanced Approved "Plasma membrane,Cytosol" "Secreted in other tissues" "Enzyme inhibitor" NA NA 18000000 "Cluster 9: Skin - Hair follicle development" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 84: Apical squamous epithelium - Cornification" 22 "Plasma membrane" Cytosol "CAB019316: , HPA044963: " "unprognostic (5.87e-2)" "unprognostic (1.49e-2)" "unprognostic (1.04e-1)" "unprognostic (7.54e-2)" "unprognostic (6.04e-2)" "unprognostic (2.50e-1)" "unprognostic (7.91e-2)" "unprognostic (1.19e-1)" "unprognostic (8.62e-3)" "unprognostic (7.85e-3)" "unprognostic (1.76e-1)" "unprognostic (2.07e-2)" "unprognostic (1.00e-2)" "unprognostic (3.46e-2)" "unprognostic (3.68e-3)" "unprognostic (1.89e-2)" "unprognostic (3.29e-1)" "unprognostic (2.33e-3)" "unprognostic (6.28e-3)" "unprognostic (2.38e-1)" "unprognostic (2.93e-2)" "unprognostic (4.29e-1)" "unprognostic (1.01e-1)" "unprognostic (1.25e-2)" "unprognostic (1.09e-1)" "unprognostic (2.44e-2)" "unprognostic (1.43e-2)" CST7 ENSG00000077984 "Cystatin F" O76096 20 24949269-24959928 "Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "bone marrow: 1033.4" "Cell type enhanced" "Detected in some" "cDC: 202.3;Mast cells: 160.9;Monocyte progenitors: 108.2;Neutrophil progenitors: 306.2;Neutrophils: 1190.7;NK-cells: 596.0;Platelets: 172.5;T-cells: 290.3" "Cell type enriched" "Detected in some" 118 "leukocyte: 192.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "gdT-cell: 1290.1" "Group enriched" "Detected in all" 27 "granulocytes: 344.2;NK-cells: 657.1;T-cells: 1290.1" "Cancer enriched" "Detected in many" 4 "Leukemia: 134.2" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Minor Salivary Gland - T-cells, Prostate - T-cells, Skeletal muscle - Neutrophils, Spleen - Neutrophils_2, Thyroid gland - T-cells" "Region enhanced" "Detected in single" "olfactory bulb: 1.9" "Low region specificity" "Detected in all" HPA040442 Enhanced "Secreted to blood" "Enzyme inhibitor" NA NA 82000 "Cluster 1: T-cells - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 25: Non-specific - Transcription" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 3 "HPA040442: " "unprognostic (4.19e-2)" "potential prognostic favorable (7.88e-4)" "unprognostic (1.32e-1)" "unprognostic (1.12e-2)" "unprognostic (1.79e-1)" "unprognostic (7.41e-2)" "potential prognostic unfavorable (8.87e-5)" "unprognostic (9.27e-2)" "potential prognostic favorable (1.93e-4)" "unprognostic (3.92e-1)" "unprognostic (9.58e-2)" "unprognostic (2.98e-2)" "unprognostic (2.17e-2)" "unprognostic (1.15e-2)" "unprognostic (7.85e-3)" "unprognostic (1.28e-2)" "unprognostic (4.40e-2)" "unprognostic (1.02e-1)" "unprognostic (3.19e-1)" "unprognostic (6.34e-2)" "unprognostic (3.48e-1)" "unprognostic (1.07e-1)" "unprognostic (8.59e-2)" "unprognostic (3.46e-2)" "unprognostic (3.29e-2)" "unprognostic (1.07e-1)" "potential prognostic favorable (1.59e-4)" "unprognostic (1.64e-1)" "unprognostic (3.80e-1)" "unprognostic (3.30e-1)" "unprognostic (2.38e-1)" CST8 "CRES, CTES5" ENSG00000125815 "Cystatin 8" O60676 20 23491101-23496010 "Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 211 "testis: 21.5" "Group enriched" "Detected in some" 38 "Early spermatids: 260.4;Late spermatids: 149.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted in male reproductive system" "Enzyme inhibitor" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 50: Lymphoma - Unknown function" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 14 CST9 "CLM, CTES7A" ENSG00000173335 "Cystatin 9" Q5W186 20 23602410-23605917 "Predicted secreted proteins" "Antimicrobial, Protease inhibitor, Thiol protease inhibitor" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 10 "breast: 1.5" "Cell type enhanced" "Detected in some" "Breast hormone-responsive cells: 1.0;Epididymal principal cells: 3.7" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 45 "Breast Invasive Carcinoma (TCGA): 14.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 17 "breast cancer: 1.7" "Breast - Breast glandular cells" HPA029190 Uncertain "Secreted in female reproductive system" "Enzyme inhibitor" NA NA "Cluster 55: Breast - Lactation" "Cluster 27: Breast cancer - Unknown function" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" "HPA029190: " "unprognostic (6.37e-2)" "unprognostic (1.10e-1)" CST9L "bA218C14.1, CTES7B" ENSG00000101435 "Cystatin 9 like" Q9H4G1 20 23564732-23568484 "Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 295 "epididymis: 24.9;testis: 85.6" "Group enriched" "Detected in some" 5 "Epididymal principal cells: 121.1;Sertoli cells: 43.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Breast Invasive Carcinoma (TCGA): 1.4;Testicular Germ Cell Tumor (TCGA): 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" "Enzyme inhibitor" NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 25 "unprognostic (1.98e-2)" "unprognostic (3.23e-2)" "unprognostic (1.34e-1)" CSTA "STF1, STFA" ENSG00000121552 "Cystatin A" P01040 3 122325248-122341969 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Protease inhibitor, Thiol protease inhibitor" "Cancer-related genes, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 1354.2;esophagus: 5787.1;vagina: 1836.0" "Group enriched" "Detected in many" 16 "Esophageal apical cells: 161499.9;Esophageal suprabasal cells: 49103.0" "Group enriched" "Detected in some" 5 "central nervous system macrophage: 1.0;leukocyte: 2.7" "Cancer enhanced" "Detected in all" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 834.3;Head and Neck Squamous Cell Carcinoma (TCGA): 1280.1" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 19 "classical monocyte: 516.2;intermediate monocyte: 269.6;myeloid DC: 383.7;neutrophil: 246.8;non-classical monocyte: 162.5" "Group enriched" "Detected in all" 193 "dendritic cells: 383.7;granulocytes: 246.8;monocytes: 516.2" "Cancer enhanced" "Detected in many" "cervical cancer: 157.7;head and neck cancer: 297.3" "Adipose subcutaneous - Adipocytes (Subcutaneous), Minor Salivary Gland - Minor salivary gland basal cells, Skin - Keratinocyte (other), Spleen - Neutrophils_2, Stomach - Gastric mucous cells, Thyroid gland - Macrophages" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000469, HPA001031, CAB047315" Enhanced Approved Nucleoplasm,Cytosol No No 12000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 24 "Nucleoplasm, Cytosol" "CAB000469: , CAB047315: , HPA001031: " "unprognostic (4.12e-1)" "unprognostic (4.38e-3)" "unprognostic (2.48e-1)" "unprognostic (9.20e-2)" "unprognostic (2.34e-1)" "unprognostic (1.45e-1)" "potential prognostic unfavorable (4.39e-4)" "unprognostic (4.90e-2)" "potential prognostic favorable (7.58e-4)" "unprognostic (8.10e-2)" "unprognostic (2.11e-3)" "unprognostic (1.45e-1)" "unprognostic (1.14e-1)" "unprognostic (2.72e-1)" "unprognostic (1.93e-1)" "unprognostic (1.27e-1)" "unprognostic (9.14e-2)" "unprognostic (2.16e-3)" "unprognostic (1.13e-1)" "unprognostic (1.54e-1)" "unprognostic (1.34e-2)" "unprognostic (6.01e-2)" "unprognostic (1.34e-2)" "unprognostic (1.79e-1)" "unprognostic (1.81e-1)" "unprognostic (7.69e-2)" "unprognostic (9.08e-2)" "unprognostic (4.83e-2)" "unprognostic (4.53e-2)" "unprognostic (1.06e-2)" "unprognostic (4.67e-2)" CSTB "CST6, EPM1, PME, STFB" ENSG00000160213 "Cystatin B" P04080 21 43772511-43776330 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Protease inhibitor, Thiol protease inhibitor" "Cancer-related genes, Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "esophagus: 20478.4" "Cell type enriched" "Detected in all" 5 "Esophageal apical cells: 413411.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017380, CAB047320, HPA058557" Enhanced Supported Nucleoli,Cytosol NA NA 6000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 21: Non-specific - Metabolism" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 85: Squamous epithelial cells - Keratinization" 4 "Nucleoli, Cytosol" "CAB047320: , HPA017380: , HPA058557: " "unprognostic (3.35e-1)" "unprognostic (2.01e-1)" "unprognostic (4.17e-2)" "unprognostic (2.67e-1)" "unprognostic (7.45e-3)" "unprognostic (1.97e-1)" "unprognostic (4.71e-3)" "unprognostic (1.80e-3)" "unprognostic (1.65e-1)" "unprognostic (2.60e-1)" "unprognostic (4.71e-3)" "unprognostic (1.46e-2)" "unprognostic (1.50e-1)" "potential prognostic unfavorable (2.88e-6)" "unprognostic (3.21e-3)" "unprognostic (2.66e-3)" "unprognostic (1.20e-2)" "unprognostic (1.93e-1)" "unprognostic (5.81e-2)" "unprognostic (9.15e-2)" "unprognostic (1.65e-2)" "unprognostic (1.19e-3)" "unprognostic (1.38e-2)" "unprognostic (1.12e-1)" "unprognostic (7.33e-2)" "unprognostic (7.86e-2)" "unprognostic (1.26e-1)" "unprognostic (1.73e-1)" "unprognostic (1.97e-1)" "unprognostic (2.91e-2)" "unprognostic (3.43e-1)" CSTF1 ENSG00000101138 "Cleavage stimulation factor subunit 1" Q05048 20 56392371-56406362 "Essential proteins, Predicted intracellular proteins" "mRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 108.8;Oocytes: 101.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019270, HPA047275, HPA065000" Supported Enhanced Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 22 Nucleoplasm "CAB019270: , HPA047275: , HPA065000: " "unprognostic (1.43e-2)" "unprognostic (1.47e-2)" "unprognostic (7.44e-3)" "unprognostic (1.06e-1)" "unprognostic (1.31e-1)" "unprognostic (3.39e-2)" "unprognostic (2.10e-1)" "unprognostic (3.19e-2)" "unprognostic (1.60e-1)" "unprognostic (1.57e-3)" "potential prognostic favorable (3.28e-6)" "unprognostic (3.04e-2)" "unprognostic (1.23e-1)" "unprognostic (1.96e-2)" "unprognostic (1.73e-3)" "unprognostic (5.55e-2)" "unprognostic (1.48e-1)" "unprognostic (1.97e-1)" "unprognostic (9.38e-2)" "unprognostic (1.97e-1)" "unprognostic (4.89e-2)" "unprognostic (1.98e-2)" "unprognostic (9.40e-2)" "unprognostic (4.39e-2)" "unprognostic (3.71e-3)" "unprognostic (2.91e-2)" "unprognostic (1.45e-1)" "unprognostic (2.38e-1)" "unprognostic (2.57e-1)" "unprognostic (1.18e-1)" "unprognostic (1.47e-1)" CSTF2 CstF-64 ENSG00000101811 "Cleavage stimulation factor subunit 2" P33240 X 100820391-100841520 "Plasma proteins, Predicted intracellular proteins" "mRNA processing" RNA-binding "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 207.3;Esophageal suprabasal cells: 54.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000427, CAB004680" Supported Enhanced "Nucleoplasm,Nuclear bodies" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 36: Non-specific - mRNA processing" "Cluster 84: Apical squamous epithelium - Cornification" 58 Nucleoplasm "Nuclear bodies" "CAB004680: , HPA000427: " "unprognostic (2.18e-1)" "unprognostic (2.30e-2)" "unprognostic (3.43e-1)" "unprognostic (2.59e-2)" "unprognostic (2.37e-1)" "unprognostic (2.19e-1)" "unprognostic (1.83e-1)" "potential prognostic favorable (2.89e-4)" "unprognostic (2.11e-2)" "potential prognostic unfavorable (9.46e-6)" "potential prognostic favorable (9.71e-5)" "unprognostic (1.82e-1)" "unprognostic (1.77e-1)" "validated prognostic unfavorable (4.03e-6)" "validated prognostic unfavorable (8.68e-5)" "unprognostic (1.67e-2)" "potential prognostic unfavorable (2.61e-5)" "unprognostic (1.27e-1)" "unprognostic (6.80e-2)" "unprognostic (3.84e-2)" "unprognostic (2.27e-1)" "unprognostic (7.25e-3)" "unprognostic (1.76e-1)" "unprognostic (1.98e-1)" "unprognostic (2.17e-2)" "unprognostic (1.40e-1)" "unprognostic (2.41e-1)" "unprognostic (3.17e-2)" "unprognostic (9.70e-2)" "unprognostic (2.47e-1)" "unprognostic (2.16e-1)" CSTF2T "CstF-64T, DKFZp434C1013, KIAA0689, tauCstF-64" ENSG00000177613 "Cleavage stimulation factor subunit 2 tau variant" Q9H0L4 10 51695486-51699595 "Predicted intracellular proteins" "mRNA processing" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 42.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039216, HPA062021" Approved Approved "Nucleoplasm,Vesicles,Basal body" No No "Cluster 1: T-cells - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 52: Non-specific - Mitochondria" "Cluster 17: Non-specific - RNA processing" 30 Nucleoplasm "Vesicles, Basal body" "HPA039216: , HPA062021: " "unprognostic (9.11e-3)" "unprognostic (2.35e-2)" "unprognostic (5.22e-2)" "unprognostic (2.93e-1)" "unprognostic (3.92e-1)" "unprognostic (9.52e-2)" "unprognostic (5.05e-2)" "potential prognostic favorable (2.25e-5)" "unprognostic (2.11e-1)" "unprognostic (2.83e-2)" "potential prognostic favorable (4.99e-5)" "unprognostic (1.08e-2)" "unprognostic (7.70e-2)" "unprognostic (1.97e-3)" "unprognostic (5.26e-2)" "unprognostic (8.45e-2)" "unprognostic (1.57e-1)" "unprognostic (1.20e-1)" "unprognostic (4.30e-3)" "unprognostic (4.33e-1)" "unprognostic (1.75e-1)" "unprognostic (4.00e-2)" "unprognostic (5.88e-2)" "unprognostic (9.07e-2)" "unprognostic (2.49e-2)" "unprognostic (1.25e-1)" "unprognostic (3.64e-1)" "unprognostic (9.99e-2)" "unprognostic (3.31e-1)" "unprognostic (6.31e-2)" "unprognostic (3.15e-1)" CSTF3 CstF-77 ENSG00000176102 "Cleavage stimulation factor subunit 3" Q12996 11 33077188-33162371 "Essential proteins, Predicted intracellular proteins" "mRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epididymal principal cells: 245.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039743, HPA040168" Enhanced Enhanced Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 22: Epididymis - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 20 Nucleoplasm "HPA039743: , HPA040168: " "unprognostic (2.93e-2)" "unprognostic (2.49e-1)" "unprognostic (2.72e-1)" "unprognostic (7.36e-2)" "unprognostic (9.57e-2)" "unprognostic (4.99e-2)" "unprognostic (3.88e-1)" "unprognostic (3.52e-2)" "unprognostic (1.38e-1)" "unprognostic (2.64e-2)" "potential prognostic unfavorable (8.34e-4)" "unprognostic (2.72e-1)" "unprognostic (2.26e-1)" "unprognostic (6.96e-3)" "unprognostic (2.80e-1)" "unprognostic (2.55e-1)" "unprognostic (1.58e-3)" "unprognostic (1.57e-2)" "unprognostic (2.99e-1)" "unprognostic (2.24e-2)" "unprognostic (2.83e-1)" "unprognostic (3.70e-1)" "unprognostic (2.65e-3)" "unprognostic (3.48e-1)" "potential prognostic favorable (5.53e-4)" "unprognostic (1.26e-1)" "unprognostic (6.26e-2)" "unprognostic (3.23e-1)" "unprognostic (1.15e-1)" "unprognostic (4.78e-2)" "unprognostic (1.27e-1)" CSTL1 "CTES1, dJ322G13.4" ENSG00000125823 "Cystatin like 1" Q9H114 20 23426104-23444930 "Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 17 "testis: 1.7" "Group enriched" "Detected in some" 9 "Early spermatids: 66.0;Late spermatids: 102.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted in male reproductive system" "Enzyme inhibitor" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 56: Non-specific - Sensory perception" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" CSTPP1 "C11orf49, FLJ22210, MGC4707" ENSG00000149179 "Centriolar satellite-associated tubulin polyglutamylase complex regulator 1" Q9H6J7 11 46936689-47164385 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Choroid plexus epithelial cells: 592.2;Respiratory ciliated cells: 554.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Skin - Keratinocyte (other), Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040051, HPA040280" Uncertain Approved "Primary cilium,Basal body,Cytosol" NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 14: Neurons - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 5 "Primary cilium, Basal body, Cytosol" "HPA040051: , HPA040280: " "unprognostic (8.21e-2)" "unprognostic (8.19e-3)" "unprognostic (1.14e-2)" "unprognostic (1.09e-1)" "unprognostic (4.38e-1)" "unprognostic (1.74e-2)" "unprognostic (1.88e-1)" "unprognostic (2.73e-1)" "unprognostic (1.53e-1)" "unprognostic (2.10e-1)" "unprognostic (1.13e-1)" "unprognostic (3.45e-1)" "unprognostic (3.94e-2)" "potential prognostic unfavorable (6.59e-4)" "unprognostic (1.25e-2)" "unprognostic (2.92e-1)" "unprognostic (3.30e-1)" "unprognostic (3.28e-1)" "unprognostic (2.62e-1)" "unprognostic (5.05e-2)" "unprognostic (1.30e-1)" "unprognostic (5.19e-2)" "unprognostic (4.95e-1)" "unprognostic (2.84e-2)" "unprognostic (6.57e-2)" "unprognostic (5.02e-2)" "unprognostic (3.02e-1)" "unprognostic (2.19e-1)" "unprognostic (9.02e-2)" "unprognostic (3.79e-2)" "unprognostic (1.30e-2)" CT45A1 "CT45-1, CT45.1" ENSG00000268940 "Cancer/testis antigen family 45 member A1" Q5HYN5 X 135713639-135723539 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 12.9" "Group enriched" "Detected in some" 9 "Differentiating spermatogonia: 6.6;Early primary spermatocytes: 7.5" "Cell type enriched" "Detected in single" 10 "endothelial cell: 9.2" "Cancer enhanced" "Detected in many" "Lung Squamous Cell Carcinoma (TCGA): 17.4;Ovary Serous Cystadenocarcinoma (TCGA): 11.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "lymphoma: 48.2" "HPA044735, HPA044757, HPA046872, HPA046987" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 67: Testis - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 18 "Nucleoplasm, Nucleoli" "HPA044735: , HPA044757: , HPA046872: , HPA046987: " "unprognostic (1.68e-2)" "unprognostic (2.30e-1)" "unprognostic (2.50e-1)" "unprognostic (2.69e-1)" "unprognostic (1.43e-2)" "unprognostic (1.58e-1)" "unprognostic (4.72e-1)" "unprognostic (5.54e-1)" CT45A10 ENSG00000269586 "Cancer/testis antigen family 45 member A10" P0DMU9 X 135881063-135893444 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 12 "testis: 8.7" "Group enriched" "Detected in some" 7 "Differentiating spermatogonia: 62.0;Early primary spermatocytes: 33.4" "Cell type enriched" "Detected in single" 21 "endothelial cell: 2.1" "Cancer enhanced" "Detected in many" "Lung Squamous Cell Carcinoma (TCGA): 10.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "HPA044735, HPA044757, HPA046872, HPA046987" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 67: Testis - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 4 "Nucleoplasm, Nucleoli" "HPA044735: , HPA044757: , HPA046872: , HPA046987: " "unprognostic (2.52e-2)" "unprognostic (1.65e-2)" "unprognostic (4.50e-1)" "unprognostic (1.19e-1)" "unprognostic (2.09e-2)" "unprognostic (5.42e-3)" "unprognostic (7.17e-1)" "unprognostic (6.45e-1)" "unprognostic (6.89e-2)" "unprognostic (4.68e-1)" "unprognostic (1.46e-3)" CT45A2 "CT45-2, CT45.2" ENSG00000271449 "Cancer/testis antigen family 45 member A2" Q5DJT8 X 135811668-135820012 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA044735, HPA044757, HPA046872, HPA046987" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 55: Lymphoma - Immune response" 1 "Nucleoplasm, Nucleoli" "HPA044735: , HPA044757: , HPA046872: , HPA046987: " CT45A3 "CT45-3, CT45-4, CT45.3, CT45.4, CT45A4" ENSG00000269096 "Cancer/testis antigen family 45 member A3" Q8NHU0 X 135759846-135768191 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 6.1" "Cell type enhanced" "Detected in single" "Differentiating spermatogonia: 1.1" "Cancer enhanced" "Detected in many" "Lung Squamous Cell Carcinoma (TCGA): 10.6;Ovary Serous Cystadenocarcinoma (TCGA): 8.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "lymphoma: 19.0;Myeloma: 17.5" "HPA044735, HPA044757, HPA046872, HPA046987" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 67: Testis - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 3 "Nucleoplasm, Nucleoli" "HPA044735: , HPA044757: , HPA046872: , HPA046987: " "unprognostic (1.38e-2)" "unprognostic (1.39e-1)" "unprognostic (1.15e-1)" "unprognostic (6.19e-1)" "unprognostic (1.83e-2)" "unprognostic (3.65e-1)" "unprognostic (5.30e-1)" "unprognostic (2.00e-2)" CT45A5 "CT45-5, CT45.5" ENSG00000228836 "Cancer/testis antigen family 45 member A5" P0DMU8 X 135775852-135785503 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.3;testis: 4.8" "Cell type enhanced" "Detected in single" "Differentiating spermatogonia: 1.1" "Cancer enhanced" "Detected in many" "Lung Squamous Cell Carcinoma (TCGA): 15.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "lymphoma: 22.7;Myeloma: 29.2" "HPA044735, HPA044757, HPA046872, HPA046987" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 48: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 5 "Nucleoplasm, Nucleoli" "HPA044735: , HPA044757: , HPA046872: , HPA046987: " "unprognostic (3.04e-1)" "unprognostic (7.53e-1)" "unprognostic (3.34e-2)" "potential prognostic unfavorable (5.42e-5)" "unprognostic (1.62e-1)" "unprognostic (6.03e-2)" "unprognostic (1.05e-1)" "unprognostic (7.89e-2)" "unprognostic (1.26e-1)" "unprognostic (3.45e-1)" "unprognostic (9.98e-2)" CT45A6 "CT45-6, CT45.6" ENSG00000278289 "Cancer/testis antigen family 45 member A6" P0DMU7 X 135794685-135802787 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 3.5;pituitary gland: 1.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA044735, HPA044757, HPA046872, HPA046987" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 55: Lymphoma - Immune response" "Nucleoplasm, Nucleoli" "HPA044735: , HPA044757: , HPA046872: , HPA046987: " "unprognostic (1.93e-1)" CT45A7 ENSG00000273696 "Cancer/testis antigen family 45 member A7" P0DMV0 X 135829229-135837280 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Lung Squamous Cell Carcinoma (TCGA): 1.5;Ovary Serous Cystadenocarcinoma (TCGA): 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 4.3" "HPA044735, HPA044757, HPA046872, HPA046987" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 51: Myeloma - Immunoglobulins" "Nucleoplasm, Nucleoli" "HPA044735: , HPA044757: , HPA046872: , HPA046987: " "unprognostic (1.56e-1)" "unprognostic (1.80e-1)" "unprognostic (2.53e-1)" CT45A8 ENSG00000278085 "Cancer/testis antigen family 45 member A8" P0DMV1 X 135846497-135854538 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "lymphoma: 9.0" "HPA044735, HPA044757, HPA046872, HPA046987" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 55: Lymphoma - Immune response" "Nucleoplasm, Nucleoli" "HPA044735: , HPA044757: , HPA046872: , HPA046987: " CT45A9 ENSG00000270946 "Cancer/testis antigen family 45 member A9" P0DMV2 X 135863418-135871812 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Lung Squamous Cell Carcinoma (TCGA): 2.2;Ovary Serous Cystadenocarcinoma (TCGA): 2.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 1.4;Sarcoma: 1.4" "HPA044735, HPA044757, HPA046872, HPA046987" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 49: HMC-1 - Innate immune response" "Cluster 104: Brain endothelial cells - Blood brain barrier" "Nucleoplasm, Nucleoli" "HPA044735: , HPA044757: , HPA046872: , HPA046987: " "unprognostic (2.23e-1)" "unprognostic (1.62e-1)" "unprognostic (4.08e-2)" "unprognostic (8.77e-2)" CT47A1 CT47.1 ENSG00000236371 "Cancer/testis antigen family 47 member A1" Q5JQC4 X 120982476-120985760 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Myeloma: 2.3" HPA042483 Supported Uncertain Nucleoli NA NA "Cluster 51: Myeloma - Immunoglobulins" Nucleoli "HPA042483: " CT47A10 CT47.10 ENSG00000224089 "Cancer/testis antigen family 47 member A10" Q5JQC4 X 120938701-120942023 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA042483 Supported Uncertain Nucleoli NA NA "Cluster 51: Myeloma - Immunoglobulins" Nucleoli "HPA042483: " CT47A11 CT47.11 ENSG00000226929 "Cancer/testis antigen family 47 member A11" Q5JQC4 X 120933840-120937158 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Liver Hepatocellular Carcinoma (TCGA): 1.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA042483 Supported Uncertain Nucleoli NA NA "Cluster 51: Myeloma - Immunoglobulins" Nucleoli "HPA042483: " "unprognostic (2.25e-1)" CT47A12 CT47.12 ENSG00000226685 "Cancer/testis antigen family 47 member A12" Q5JQC4 X 120930250-120932301 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 11 "testis: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 2.6;Sarcoma: 1.5" HPA042483 Supported Uncertain Nucleoli NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" Nucleoli "HPA042483: " CT47A2 CT47.2 ENSG00000242362 "Cancer/testis antigen family 47 member A2" Q5JQC4 X 120977606-120980928 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA042483 Supported Uncertain Nucleoli NA NA "Cluster 51: Myeloma - Immunoglobulins" Nucleoli "HPA042483: " CT47A3 CT47.3 ENSG00000236126 "Cancer/testis antigen family 47 member A3" Q5JQC4 X 120972746-120976068 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA042483 Supported Uncertain Nucleoli NA NA "Cluster 51: Myeloma - Immunoglobulins" Nucleoli "HPA042483: " CT47A4 CT47.4 ENSG00000230594 "Cancer/testis antigen family 47 member A4" Q5JQC4 X 120967886-120971208 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA042483 Supported Uncertain Nucleoli NA NA "Cluster 51: Myeloma - Immunoglobulins" Nucleoli "HPA042483: " CT47A5 CT47.5 ENSG00000237957 "Cancer/testis antigen family 47 member A5" Q5JQC4 X 120963026-120966348 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA042483 Supported Uncertain Nucleoli NA NA "Cluster 51: Myeloma - Immunoglobulins" Nucleoli "HPA042483: " CT47A6 CT47.6 ENSG00000226023 "Cancer/testis antigen family 47 member A6" Q5JQC4 X 120958165-120961487 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Myeloma: 1.3" HPA042483 Supported Uncertain Nucleoli NA NA "Cluster 51: Myeloma - Immunoglobulins" "Cluster 106: Spermatogonia - Spermatogonial differentiation" Nucleoli "HPA042483: " CT47A7 CT47.7 ENSG00000228517 "Cancer/testis antigen family 47 member A7" Q5JQC4 X 120953282-120956600 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA042483 Supported Uncertain Nucleoli NA NA Nucleoli "HPA042483: " CT47A8 CT47.8 ENSG00000230347 "Cancer/testis antigen family 47 member A8" Q5JQC4 X 120948422-120951744 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA042483 Supported Uncertain Nucleoli NA NA "Cluster 51: Myeloma - Immunoglobulins" Nucleoli "HPA042483: " CT47A9 CT47.9 ENSG00000226600 "Cancer/testis antigen family 47 member A9" Q5JQC4 X 120943561-120946883 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA042483 Supported Uncertain Nucleoli NA NA "Cluster 51: Myeloma - Immunoglobulins" Nucleoli "HPA042483: " CT47B1 CT47.13 ENSG00000236446 "Cancer/testis antigen family 47 member B1" P0C2W7 X 120872607-120875866 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 71 "testis: 7.0" "Cell type enriched" "Detected in some" 5 "Early primary spermatocytes: 120.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA042483 Supported Uncertain Nucleoli NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 3: Early primary spermatocytes - Early meiosis" Nucleoli "HPA042483: " CT55 "CXorf48, FLJ20527" ENSG00000169551 "Cancer/testis antigen 55" Q8WUE5 X 135156540-135171398 "Predicted intracellular proteins" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 10 "testis: 3.6" "Group enriched" "Detected in some" 4 "Differentiating spermatogonia: 7.8;Early primary spermatocytes: 15.9" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in single" "Skin Cutaneous Melanoma (TCGA): 1.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 3.7;Sarcoma: 3.7;skin cancer: 7.1" "Testis - Spermatocytes" HPA059575 Approved Vesicles NA NA "Cluster 67: Testis - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 3: Early primary spermatocytes - Early meiosis" 23 Vesicles "HPA059575: " "unprognostic (1.32e-1)" CT83 "CXorf61, FLJ20611, FLJ22913, KK-LC-1" ENSG00000204019 "Cancer/testis antigen 83" Q5H943 X 116461686-116462976 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 25 "testis: 66.2" "Cell type enriched" "Detected in some" 5 "Late spermatids: 4893.7" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 15.9;Stomach Adenocarcinoma (TCGA): 13.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 37.9" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 7: Liver cancer - Metabolism" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" "unprognostic (5.22e-3)" "unprognostic (1.51e-1)" "unprognostic (1.12e-1)" "unprognostic (6.03e-1)" "unprognostic (8.22e-2)" "unprognostic (1.18e-3)" "unprognostic (1.05e-1)" "unprognostic (3.28e-1)" "unprognostic (3.80e-1)" "unprognostic (1.15e-1)" "unprognostic (8.12e-2)" "unprognostic (3.72e-1)" "unprognostic (9.36e-3)" "unprognostic (1.40e-1)" CTAG1A "ESO1, LAGE2A" ENSG00000268651 "Cancer/testis antigen 1A" P78358 X 154585133-154586816 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 79 "testis: 7.8" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 12.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 145.3" "CAB013061, HPA063039" Enhanced Uncertain "Golgi apparatus,Vesicles" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" 58 "Golgi apparatus, Vesicles" "CAB013061: , HPA063039: " "unprognostic (1.30e-1)" "unprognostic (3.02e-1)" "unprognostic (2.31e-3)" "unprognostic (7.39e-1)" "unprognostic (3.82e-1)" "unprognostic (1.13e-1)" "unprognostic (3.19e-1)" "unprognostic (5.24e-1)" "unprognostic (1.07e-1)" CTAG1B "CT6.1, CTAG, CTAG1, ESO1, LAGE2A, LAGE2B, NY-ESO-1" ENSG00000184033 "Cancer/testis antigen 1B" P78358 X 154617609-154619282 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 25 "testis: 7.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "Myeloma: 64.7" "CAB015453, HPA063039" Enhanced Uncertain "Golgi apparatus,Vesicles" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 20: Myeloma - Immune response" 60 "Golgi apparatus, Vesicles" "CAB015453: , HPA063039: " "unprognostic (8.80e-3)" "unprognostic (2.60e-2)" "unprognostic (3.28e-2)" "unprognostic (2.94e-1)" "unprognostic (3.66e-1)" "unprognostic (1.59e-1)" "unprognostic (2.52e-1)" "unprognostic (7.08e-2)" "unprognostic (3.04e-1)" "unprognostic (2.99e-1)" "unprognostic (5.45e-2)" "unprognostic (7.43e-1)" CTAG2 "CAMEL, CT6.2a, CT6.2b, ESO2, LAGE-1, LAGE-1a, LAGE-1b, LAGE1, MGC138724, MGC3803" ENSG00000126890 "Cancer/testis antigen 2" O75638 X 154651972-154653579 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 5.0;testis: 10.2" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 88.6;Early primary spermatocytes: 35.6;Esophageal suprabasal cells: 8.2;Extravillous trophoblasts: 14.3;Oocytes: 13.8;Submucosal glandular cells: 15.3;Undifferentiated spermatogonia: 51.0" "Cell type enhanced" "Detected in some" "leukocyte: 3.6" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 25.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 186.5" HPA071467 Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 2 Vesicles Nucleoplasm "HPA071467: " "unprognostic (1.27e-2)" "unprognostic (2.62e-1)" "unprognostic (5.03e-1)" "unprognostic (1.59e-1)" "potential prognostic unfavorable (1.50e-4)" "unprognostic (1.43e-2)" "unprognostic (3.59e-1)" "unprognostic (2.81e-1)" "unprognostic (1.32e-1)" "unprognostic (7.67e-2)" "unprognostic (3.94e-1)" "unprognostic (4.77e-1)" "unprognostic (9.41e-1)" "unprognostic (7.53e-1)" "unprognostic (4.74e-1)" "unprognostic (5.77e-1)" "unprognostic (1.70e-1)" CTAGE1 "CT21.1, CT21.2, CTAGE, cTAGE-1, cTAGE-2" ENSG00000212710 "Cutaneous T cell lymphoma-associated antigen 1" "Q96RT6, Q9HC47" 18 22413599-22417915 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 98 "testis: 9.8" "Group enriched" "Detected in some" 10 "Distal convoluted tubule cells: 1.9;Loop of henle epithelial cells: 2.3;Papillary tip epithelial cells: 2.0;Podocytes: 1.8;Proximal tubule cells: 6.7;Renal collecting duct intercalated cells: 2.2;Renal collecting duct principal cells: 2.5;Renal connecting tubule cells: 2.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells" "HPA000387, HPA000922, CAB016204" Uncertain NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 88: Proximal tubular cells - Transmembrane transport" 1 "CAB016204: , HPA000387: , HPA000922: " CTAGE15 CTAGE15P ENSG00000271079 "CTAGE family member 15" A4D2H0 7 143571801-143574387 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "testis: 7.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA000387, HPA000922" Uncertain NA NA "Cluster 79: Testis - Spermatogenesis" "HPA000387: , HPA000922: " CTAGE4 "cTAGE-4, FLJ43692" ENSG00000288784 "CTAGE family member 4" Q8IX94 7 144183466-144186080 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "skin 1: 9.8" "Cell type enhanced" "Detected in single" "Respiratory deuterosomal cells: 1.0" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "HPA000387, HPA000922" Uncertain NA NA "Cluster 21: Testis - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" "HPA000387: , HPA000922: " CTAGE6 "CTAGE6P, MGC41943" ENSG00000271321 "CTAGE family member 6" Q86UF2 7 143755089-143757696 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 63 "testis: 13.8" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA000387, HPA000922" Uncertain NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 102: Non-specific - Mixed function" 1 "HPA000387: , HPA000922: " "unprognostic (1.28e-1)" "unprognostic (2.34e-1)" CTAGE8 ENSG00000289604 "CTAGE family member 8" P0CG41 7 144266674-144269288 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "skin 1: 6.4;thyroid gland: 4.8" "Not detected" "Not detected" "Region enriched" "Detected in single" 4 "choroid plexus: 3.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "HPA000387, HPA000922" Uncertain NA NA "Cluster 47: Testis - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 30: Non-specific - Gene expression regulation" 1 "HPA000387: , HPA000922: " CTAGE9 ENSG00000236761 "CTAGE family member 9" A4FU28 6 131708441-131711017 "Essential proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 21 "testis: 9.0" "Cell type enriched" "Detected in some" 4 "Late primary spermatocytes: 22.4" "Cancer enhanced" "Detected in single" "Kidney Renal Clear Cell Carcinoma (TCGA): 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA000387, HPA000922" Uncertain NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" "HPA000387: , HPA000922: " "unprognostic (7.02e-2)" "unprognostic (1.49e-1)" "unprognostic (1.80e-2)" CTBP1 BARS ENSG00000159692 "C-terminal binding protein 1" Q13363 4 1211445-1250333 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Differentiation, Host-virus interaction, Transcription, Transcription regulation" "Oxidoreductase, Repressor" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004217, HPA018987, HPA044971" Approved Enhanced Nucleoplasm NA NA 6500 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 64: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 17: Non-specific - RNA processing" 161 Nucleoplasm "CAB004217: , HPA018987: , HPA044971: " "unprognostic (3.99e-3)" "unprognostic (8.57e-2)" "unprognostic (5.27e-2)" "unprognostic (1.52e-1)" "unprognostic (2.13e-1)" "unprognostic (1.86e-1)" "unprognostic (2.14e-1)" "unprognostic (1.04e-2)" "unprognostic (6.40e-2)" "unprognostic (7.86e-2)" "unprognostic (3.61e-2)" "unprognostic (3.53e-2)" "unprognostic (5.42e-3)" "unprognostic (1.95e-2)" "unprognostic (3.76e-2)" "unprognostic (1.08e-1)" "unprognostic (4.94e-3)" "unprognostic (6.54e-3)" "unprognostic (1.86e-1)" "unprognostic (5.87e-2)" "potential prognostic favorable (6.81e-4)" "unprognostic (1.78e-3)" "unprognostic (2.29e-1)" "unprognostic (7.07e-2)" "unprognostic (1.76e-1)" "unprognostic (3.17e-2)" "unprognostic (2.35e-1)" "unprognostic (6.51e-2)" "unprognostic (7.42e-2)" "unprognostic (1.32e-1)" "unprognostic (2.01e-2)" CTBP2 ribeye ENSG00000175029 "C-terminal binding protein 2" P56545 10 124984317-125161170 "Plasma proteins, Predicted intracellular proteins" "Differentiation, Host-virus interaction, Transcription, Transcription regulation" "Oxidoreductase, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 997.7;Endometrial luminal cells: 863.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Skin - Endothelial cells, Spleen - Endothelial cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023559, HPA023564, CAB031916, HPA044971, CAB079018" Approved Approved Approved Nucleoplasm NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 51: Secretory epithelial cells - Mixed function" 135 Nucleoplasm "CAB031916: , CAB079018: , HPA023559: , HPA023564: , HPA044971: " "unprognostic (4.26e-2)" "unprognostic (2.24e-1)" "unprognostic (5.12e-2)" "unprognostic (4.32e-2)" "unprognostic (1.71e-1)" "unprognostic (6.58e-2)" "unprognostic (1.11e-1)" "potential prognostic favorable (9.76e-4)" "unprognostic (1.33e-2)" "unprognostic (2.18e-1)" "potential prognostic favorable (5.76e-9)" "unprognostic (2.22e-3)" "unprognostic (2.35e-1)" "unprognostic (6.15e-2)" "unprognostic (1.48e-1)" "validated prognostic unfavorable (2.15e-4)" "validated prognostic unfavorable (8.42e-4)" "unprognostic (1.15e-1)" "unprognostic (3.00e-1)" "unprognostic (1.18e-1)" "potential prognostic unfavorable (1.57e-4)" "unprognostic (3.09e-2)" "unprognostic (1.05e-1)" "unprognostic (1.09e-2)" "unprognostic (2.28e-2)" "unprognostic (9.45e-3)" "unprognostic (8.40e-2)" "unprognostic (2.66e-1)" "unprognostic (2.25e-1)" "unprognostic (2.51e-1)" "unprognostic (1.60e-2)" CTBS CTB ENSG00000117151 Chitobiase Q01459 1 84549611-84574480 "Plasma proteins, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast lactating cells: 69.2;Microglia: 64.6;Neutrophils: 200.5;Retinal pigment epithelial cells: 89.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 7 "basal ganglia: 9.8" "CAB017043, HPA023594, HPA048810" Approved Uncertain Cytosol "Intracellular and membrane" Enzyme NA NA 160000000 "Cluster 22: Epididymis - Mixed function" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 37: Non-specific - mRNA processing" "Cluster 24: Neutrophils - Innate immunity signal integration" 12 Cytosol "CAB017043: , HPA023594: , HPA048810: " "unprognostic (3.40e-1)" "unprognostic (1.25e-1)" "potential prognostic unfavorable (5.70e-4)" "potential prognostic favorable (7.85e-4)" "unprognostic (3.16e-2)" "unprognostic (2.46e-2)" "unprognostic (9.94e-2)" "unprognostic (5.85e-2)" "unprognostic (2.69e-2)" "unprognostic (1.09e-2)" "unprognostic (8.36e-2)" "unprognostic (5.89e-2)" "unprognostic (2.58e-1)" "unprognostic (8.59e-2)" CTC1 "AAF132, C17orf68, FLJ22170" ENSG00000178971 "CST telomere replication complex component 1" Q2NKJ3 17 8224815-8248058 "Disease related genes, Human disease related genes, Predicted intracellular proteins" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "pDCs: 61.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052436 Supported Nucleoplasm,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 6: Leukemia - Signal transduction" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 8 Nucleoplasm Cytosol "HPA052436: " "unprognostic (9.69e-2)" "unprognostic (9.21e-2)" "unprognostic (2.33e-1)" "unprognostic (2.11e-2)" "unprognostic (1.05e-1)" "unprognostic (1.02e-1)" "unprognostic (1.60e-2)" "unprognostic (2.22e-2)" "unprognostic (3.47e-2)" "unprognostic (9.73e-2)" "unprognostic (8.23e-3)" "unprognostic (1.04e-2)" "unprognostic (1.08e-1)" "unprognostic (1.53e-3)" "unprognostic (1.07e-1)" "unprognostic (1.60e-1)" "unprognostic (3.47e-1)" "unprognostic (3.08e-3)" "unprognostic (3.81e-2)" "unprognostic (3.08e-2)" "potential prognostic favorable (1.68e-5)" "unprognostic (2.41e-3)" "unprognostic (2.54e-3)" "unprognostic (2.46e-1)" "unprognostic (1.11e-1)" "unprognostic (1.09e-1)" "unprognostic (3.43e-1)" "unprognostic (1.78e-1)" "unprognostic (9.70e-2)" "unprognostic (1.20e-1)" CTCF "CFAP108, FAP108" ENSG00000102974 "CCCTC-binding factor" P49711 16 67562467-67639177 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Chromosome partition, Transcription, Transcription regulation" "Activator, Chromatin regulator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Intellectual disability, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004122, CAB062550, CAB068181, CAB068182" Supported Supported Nucleoplasm NA NA 5100 "Cluster 41: Basophils - Unknown function" "Cluster 80: Thymus - Adaptive immune response" "Cluster 34: Non-specific - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 301 Nucleoplasm "CAB062550: , CAB068181: , CAB068182: , HPA004122: " "unprognostic (5.70e-2)" "unprognostic (7.96e-2)" "unprognostic (3.34e-1)" "unprognostic (3.01e-1)" "unprognostic (1.82e-1)" "unprognostic (5.24e-2)" "unprognostic (7.98e-2)" "unprognostic (9.54e-3)" "unprognostic (7.74e-2)" "unprognostic (2.73e-1)" "potential prognostic favorable (9.67e-8)" "unprognostic (1.75e-3)" "unprognostic (2.53e-1)" "unprognostic (1.54e-3)" "unprognostic (1.08e-1)" "unprognostic (9.95e-2)" "unprognostic (1.51e-3)" "unprognostic (4.92e-2)" "unprognostic (5.01e-2)" "unprognostic (1.87e-1)" "unprognostic (4.08e-2)" "unprognostic (1.03e-2)" "unprognostic (2.22e-2)" "unprognostic (1.06e-1)" "unprognostic (1.95e-1)" "unprognostic (3.03e-1)" "unprognostic (3.57e-2)" "unprognostic (1.57e-1)" "unprognostic (3.04e-1)" "unprognostic (8.94e-3)" "unprognostic (1.19e-1)" CTCFL "BORIS, CT27, dJ579F20.2" ENSG00000124092 "CCCTC-binding factor like" Q8NI51 20 57495966-57525652 "Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "Activator, Chromatin regulator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 11 "testis: 10.4" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 171.1;Early primary spermatocytes: 132.7;Oocytes: 18.4;Undifferentiated spermatogonia: 40.2" "Cell type enriched" "Detected in single" 5 "Bergmann glia: 2.9" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 9.2;Ovary Serous Cystadenocarcinoma (TCGA): 14.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Bone cancer: 19.0;cervical cancer: 18.4" "Testis - Spermatocytes, Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" HPA001472 Enhanced Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 57: Testis - Spermatogenesis" "Cluster 9: Non-specific - Receptor signaling" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 6 "Nucleoplasm, Nuclear bodies" Cytosol "HPA001472: " "unprognostic (1.93e-1)" "unprognostic (1.36e-2)" "unprognostic (1.27e-1)" "unprognostic (1.30e-1)" "unprognostic (1.50e-2)" "unprognostic (5.09e-3)" "unprognostic (4.97e-2)" "unprognostic (2.16e-1)" "unprognostic (3.48e-2)" "unprognostic (1.66e-2)" "unprognostic (1.79e-1)" "unprognostic (1.05e-1)" "unprognostic (1.47e-1)" "unprognostic (1.45e-1)" CTDNEP1 "DULLARD, HSA011916, NET56" ENSG00000175826 "CTD nuclear envelope phosphatase 1" O95476 17 7243591-7252491 "Enzymes, Essential proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 395.2" "Cell type enhanced" "Detected in many" "Bergmann glia: 22.1;Brain excitatory neurons: 19.0;Brain inhibitory neurons: 18.7;Ependymal cells: 22.2;Microglia: 20.1;Oligodendrocyte progenitor cells: 20.5;Oligodendrocytes: 27.2;Other brain neurons: 19.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037439, HPA066466" Uncertain Approved "Lipid droplets" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 24: Non-specific - Transcription" "Cluster 19: Astrocytes - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" 3 "Lipid droplets" "HPA037439: , HPA066466: " "unprognostic (9.60e-3)" "unprognostic (2.65e-1)" "unprognostic (2.53e-2)" "unprognostic (1.07e-1)" "unprognostic (1.41e-1)" "unprognostic (1.06e-1)" "unprognostic (1.82e-1)" "unprognostic (1.06e-1)" "unprognostic (1.65e-1)" "unprognostic (4.79e-3)" "unprognostic (3.78e-3)" "unprognostic (3.18e-1)" "unprognostic (5.20e-3)" "unprognostic (3.75e-2)" "unprognostic (1.00e-2)" "unprognostic (1.64e-1)" "unprognostic (8.48e-2)" "unprognostic (2.68e-1)" "unprognostic (9.66e-2)" "unprognostic (7.89e-2)" "unprognostic (1.89e-2)" "unprognostic (1.59e-2)" "unprognostic (8.16e-2)" "unprognostic (3.76e-1)" "unprognostic (2.41e-1)" "unprognostic (5.61e-2)" "unprognostic (1.36e-1)" "unprognostic (9.39e-2)" "unprognostic (1.82e-2)" "unprognostic (2.37e-2)" CTDP1 FCP1 ENSG00000060069 "CTD phosphatase subunit 1" Q9Y5B0 18 79679803-79754503 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Hydrolase, Protein phosphatase" "Cataract, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 78.4;Late primary spermatocytes: 83.8;Neutrophils: 147.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032641, HPA040394, HPA070389" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 47: Testis - Mixed function" "Cluster 18: Non-specific - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 32 Nucleoplasm Vesicles "CAB032641: , HPA040394: , HPA070389: " "unprognostic (6.95e-2)" "unprognostic (1.55e-1)" "unprognostic (8.22e-2)" "unprognostic (3.44e-3)" "unprognostic (4.39e-2)" "unprognostic (2.68e-1)" "unprognostic (5.50e-2)" "unprognostic (1.57e-3)" "unprognostic (3.81e-1)" "unprognostic (1.59e-1)" "unprognostic (2.42e-3)" "unprognostic (9.66e-2)" "unprognostic (2.35e-2)" "potential prognostic unfavorable (5.72e-4)" "unprognostic (2.48e-2)" "unprognostic (3.96e-2)" "unprognostic (1.93e-1)" "unprognostic (4.11e-1)" "unprognostic (3.04e-2)" "unprognostic (3.46e-2)" "unprognostic (1.27e-1)" "unprognostic (3.00e-2)" "unprognostic (2.64e-1)" "unprognostic (4.05e-2)" "unprognostic (1.30e-1)" "unprognostic (1.00e-1)" "unprognostic (3.62e-2)" "unprognostic (7.60e-2)" "unprognostic (2.98e-1)" "unprognostic (2.53e-3)" "unprognostic (1.53e-1)" CTDSP1 "NLIIF, SCP1" ENSG00000144579 "CTD small phosphatase 1" Q9GZU7 2 218398256-218405941 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Platelets: 146.7" "Cell type enhanced" "Detected in many" "pericyte: 68.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062654 Supported Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 29 Nucleoplasm "HPA062654: " "unprognostic (4.84e-3)" "unprognostic (5.53e-2)" "unprognostic (9.66e-2)" "unprognostic (1.33e-1)" "unprognostic (2.26e-2)" "unprognostic (1.73e-1)" "unprognostic (2.12e-1)" "unprognostic (3.64e-2)" "unprognostic (6.58e-2)" "unprognostic (2.15e-1)" "validated prognostic favorable (1.54e-6)" "validated prognostic favorable (7.75e-4)" "unprognostic (1.52e-2)" "unprognostic (1.70e-2)" "unprognostic (3.25e-2)" "unprognostic (3.93e-2)" "potential prognostic unfavorable (2.92e-4)" "unprognostic (1.79e-1)" "unprognostic (2.89e-1)" "unprognostic (2.62e-2)" "unprognostic (1.97e-1)" "unprognostic (2.10e-1)" "unprognostic (1.25e-1)" "unprognostic (2.20e-1)" "unprognostic (1.30e-1)" "unprognostic (5.71e-2)" "unprognostic (1.44e-1)" "unprognostic (6.26e-2)" "unprognostic (1.55e-1)" "unprognostic (5.47e-2)" "unprognostic (2.41e-1)" CTDSP2 "OS4, PSR2, SCP2" ENSG00000175215 "CTD small phosphatase 2" O14595 12 57819927-57846729 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 255.0;Platelets: 214.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052607 Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 41: Basophils - Unknown function" "Cluster 49: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 11 Nucleoplasm Mitochondria "HPA052607: " "unprognostic (1.42e-1)" "unprognostic (5.94e-2)" "unprognostic (2.37e-1)" "unprognostic (6.73e-2)" "unprognostic (1.33e-2)" "unprognostic (1.46e-2)" "unprognostic (1.39e-1)" "unprognostic (1.53e-1)" "unprognostic (8.83e-2)" "unprognostic (1.21e-2)" "validated prognostic favorable (1.81e-5)" "validated prognostic favorable (2.83e-4)" "unprognostic (3.94e-2)" "unprognostic (3.38e-3)" "potential prognostic unfavorable (3.55e-4)" "unprognostic (5.87e-2)" "unprognostic (1.53e-3)" "unprognostic (7.19e-3)" "unprognostic (1.26e-1)" "unprognostic (1.31e-2)" "unprognostic (1.74e-2)" "unprognostic (5.46e-2)" "unprognostic (9.70e-2)" "unprognostic (4.56e-1)" "unprognostic (6.69e-3)" "unprognostic (1.36e-1)" "unprognostic (6.54e-2)" "unprognostic (2.04e-1)" "unprognostic (2.02e-1)" "unprognostic (5.93e-2)" "unprognostic (9.87e-2)" CTDSPL "C3orf8, HYA22, PSR1, RBSP3, SCP3" ENSG00000144677 "CTD small phosphatase like" O15194 3 37861880-37984469 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal convoluted tubule cells: 545.0;Platelets: 580.4;Podocytes: 1302.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048325 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 58: Skin - Keratinization" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 57: Podocytes - Glomerular filtration" 2 Vesicles Nucleoplasm "HPA048325: " "unprognostic (2.00e-3)" "unprognostic (1.26e-1)" "unprognostic (3.92e-2)" "unprognostic (3.93e-1)" "unprognostic (3.76e-2)" "unprognostic (8.66e-2)" "unprognostic (1.82e-1)" "unprognostic (3.22e-1)" "unprognostic (5.91e-2)" "unprognostic (3.92e-1)" "validated prognostic favorable (7.54e-10)" "validated prognostic favorable (8.90e-7)" "unprognostic (6.08e-3)" "unprognostic (2.04e-3)" "potential prognostic unfavorable (2.41e-4)" "unprognostic (1.01e-1)" "unprognostic (2.12e-1)" "unprognostic (3.08e-1)" "unprognostic (3.21e-1)" "unprognostic (2.94e-1)" "unprognostic (5.64e-2)" "unprognostic (2.25e-2)" "unprognostic (1.07e-1)" "unprognostic (2.23e-1)" "unprognostic (5.48e-2)" "unprognostic (2.24e-2)" "unprognostic (2.77e-1)" "unprognostic (9.33e-2)" "unprognostic (1.90e-1)" "unprognostic (5.92e-2)" "unprognostic (8.10e-2)" CTDSPL2 "FLJ10523, HSPC129" ENSG00000137770 "CTD small phosphatase like 2" Q05D32 15 44427622-44529038 "Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040763, HPA062198" Approved Approved Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" 22 Nucleoplasm "HPA040763: , HPA062198: " "unprognostic (1.30e-1)" "unprognostic (1.61e-1)" "unprognostic (4.87e-2)" "unprognostic (3.93e-1)" "unprognostic (1.64e-1)" "unprognostic (1.46e-2)" "unprognostic (1.98e-2)" "unprognostic (1.96e-2)" "unprognostic (1.74e-1)" "potential prognostic unfavorable (9.46e-4)" "potential prognostic favorable (9.68e-5)" "unprognostic (9.74e-3)" "unprognostic (4.31e-1)" "unprognostic (3.77e-2)" "unprognostic (4.04e-2)" "unprognostic (8.43e-2)" "unprognostic (2.23e-2)" "unprognostic (3.71e-1)" "unprognostic (2.67e-2)" "unprognostic (2.85e-2)" "unprognostic (1.96e-2)" "unprognostic (1.13e-3)" "potential prognostic unfavorable (2.66e-4)" "unprognostic (5.72e-2)" "unprognostic (1.19e-2)" "unprognostic (8.50e-2)" "unprognostic (2.77e-2)" "unprognostic (8.05e-2)" "unprognostic (3.19e-1)" "unprognostic (4.41e-3)" "unprognostic (1.36e-1)" CTF1 "CT-1, CT1" ENSG00000150281 "Cardiotrophin 1" Q16619 16 30896614-30903547 "Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 17.7;Epididymal basal cells: 21.0;Fallopian secretory cells: 17.8;Fallopian tube ciliated cells: 18.0;Müller glia: 17.2;Respiratory ciliated cells: 18.9;Smooth muscle cells: 21.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Liver - Hepatic stellate cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025853 Uncertain "Secreted to blood" Cytokine NA NA 11900 "Cluster 75: Ovary - Mixed function" "Cluster 44: Non-specific - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 62: Smooth muscle cells - Muscle contraction" 3 "CAB025853: " "potential prognostic favorable (9.27e-4)" "unprognostic (2.18e-1)" "unprognostic (6.42e-2)" "unprognostic (2.39e-1)" "potential prognostic unfavorable (3.93e-4)" "unprognostic (2.11e-1)" "validated prognostic unfavorable (2.96e-4)" "validated prognostic unfavorable (1.77e-6)" "unprognostic (2.48e-2)" "unprognostic (2.07e-1)" "unprognostic (1.67e-2)" "unprognostic (2.67e-1)" "unprognostic (1.21e-2)" "potential prognostic favorable (1.08e-4)" "unprognostic (1.80e-1)" "unprognostic (6.18e-2)" "unprognostic (1.97e-1)" "unprognostic (5.00e-2)" "unprognostic (1.23e-1)" "unprognostic (1.84e-1)" "unprognostic (3.64e-2)" "unprognostic (5.22e-2)" "unprognostic (1.87e-1)" "unprognostic (6.94e-2)" "unprognostic (2.06e-1)" "unprognostic (3.49e-3)" "unprognostic (1.72e-1)" "unprognostic (1.71e-2)" "unprognostic (1.64e-2)" CTH CSE ENSG00000116761 "Cystathionine gamma-lyase" P32929 1 70411218-70439851 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Cysteine biosynthesis, Lipid metabolism" "Calmodulin-binding, Lyase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "liver: 115.0" "Cell type enhanced" "Detected in many" "Bergmann glia: 71.1;Cone photoreceptor cells: 70.4;Endometrial ciliated cells: 81.8;Hepatocytes: 188.6;Ovarian stromal cells: 80.7;Pancreatic acinar cells: 89.6;Vascular smooth muscle cells: 67.9" "Cell type enhanced" "Detected in all" "Bergmann glia: 74.3" "Group enriched" "Detected in all" 4 "Liver Hepatocellular Carcinoma (TCGA): 41.6;Testicular Germ Cell Tumor (TCGA): 12.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021591, HPA023300" Enhanced NA NA 290000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 1: Neurons - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 103: Non-specific - Basic cellular processes" 4 "HPA021591: , HPA023300: " "unprognostic (6.93e-3)" "unprognostic (1.42e-1)" "unprognostic (5.03e-1)" "unprognostic (9.15e-3)" "unprognostic (6.22e-2)" "unprognostic (7.49e-2)" "unprognostic (1.96e-1)" "unprognostic (1.84e-1)" "unprognostic (3.13e-3)" "unprognostic (1.04e-1)" "potential prognostic favorable (2.96e-4)" "unprognostic (1.29e-1)" "unprognostic (2.53e-2)" "unprognostic (2.95e-3)" "unprognostic (8.60e-3)" "unprognostic (4.00e-2)" "unprognostic (1.04e-2)" "unprognostic (2.46e-1)" "unprognostic (7.32e-3)" "unprognostic (3.11e-1)" "unprognostic (3.74e-2)" "unprognostic (3.35e-3)" "unprognostic (1.08e-1)" "unprognostic (5.63e-3)" "unprognostic (2.77e-2)" "unprognostic (2.40e-1)" "unprognostic (2.94e-1)" "unprognostic (5.95e-2)" "unprognostic (9.35e-2)" "unprognostic (2.77e-3)" "unprognostic (1.25e-1)" CTHRC1 ENSG00000164932 "Collagen triple helix repeat containing 1" Q96CG8 8 103371538-103382989 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 82.1;placenta: 84.5;urinary bladder: 78.9" "Cell type enhanced" "Detected in many" "Epicardial cells: 43.2;Fibroblasts: 141.1;Hepatic stellate cells: 277.6;Lymphatic endothelial cells: 80.3;Pericytes: 37.0;Plasma cells: 76.4;Thymocytes: 52.5;Vascular endothelial cells: 42.4" "Cell type enhanced" "Detected in many" "fibroblast: 37.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 2.3" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in all" "skin cancer: 166.9" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells, Lung - Fibroblasts_2, Minor Salivary Gland - Macrophages, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059806, HPA061896" Approved Approved Nucleoplasm "Secreted in other tissues" "No annotated function" NA NA 4600000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 37: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 7 Nucleoplasm "HPA059806: , HPA061896: " "unprognostic (7.42e-2)" "unprognostic (2.82e-2)" "unprognostic (3.18e-2)" "unprognostic (1.43e-1)" "unprognostic (7.03e-3)" "unprognostic (1.62e-1)" "unprognostic (7.61e-2)" "unprognostic (5.85e-3)" "unprognostic (2.05e-2)" "unprognostic (1.65e-2)" "potential prognostic unfavorable (9.58e-4)" "unprognostic (3.15e-2)" "potential prognostic unfavorable (2.50e-4)" "potential prognostic unfavorable (4.75e-4)" "unprognostic (1.58e-1)" "unprognostic (6.93e-3)" "potential prognostic unfavorable (1.17e-4)" "unprognostic (1.50e-1)" "unprognostic (7.03e-2)" "unprognostic (7.12e-3)" "potential prognostic unfavorable (1.12e-4)" "unprognostic (6.36e-2)" "unprognostic (1.58e-1)" "unprognostic (2.17e-2)" "unprognostic (1.50e-1)" "unprognostic (2.65e-3)" "unprognostic (3.38e-2)" "potential prognostic unfavorable (1.82e-4)" "unprognostic (3.89e-2)" "potential prognostic unfavorable (8.13e-4)" "unprognostic (2.24e-1)" CTIF KIAA0427 ENSG00000134030 "Cap binding complex dependent translation initiation factor" O43310 18 48539031-48863217 "Predicted intracellular proteins, Transporters" "Nonsense-mediated mRNA decay, Translation regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 165.2;Bergmann glia: 149.8;Brain excitatory neurons: 121.4;Brain inhibitory neurons: 124.9;Choroid plexus epithelial cells: 108.3;Distal convoluted tubule cells: 97.2;Loop of henle epithelial cells: 104.6;Oligodendrocyte progenitor cells: 125.3;Oligodendrocytes: 95.3;Other brain neurons: 168.4;Podocytes: 52.1;Proximal tubule cells: 68.1;Renal collecting duct principal cells: 54.4;Renal connecting tubule cells: 76.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Minor Salivary Gland - Minor salivary glandular cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016865, HPA024801" Uncertain Supported Cytosol NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 102: Non-specific - Mixed function" 8 Cytosol "HPA016865: , HPA024801: " "unprognostic (1.83e-1)" "unprognostic (1.72e-1)" "unprognostic (1.17e-1)" "unprognostic (5.59e-2)" "unprognostic (5.39e-2)" "unprognostic (3.79e-1)" "potential prognostic favorable (4.25e-5)" "unprognostic (2.64e-1)" "unprognostic (2.63e-1)" "potential prognostic favorable (2.86e-4)" "unprognostic (3.95e-3)" "potential prognostic favorable (2.50e-4)" "unprognostic (4.40e-2)" "unprognostic (3.60e-2)" "unprognostic (1.37e-1)" "unprognostic (3.18e-1)" "unprognostic (1.14e-3)" "unprognostic (1.37e-1)" "unprognostic (1.72e-2)" "unprognostic (2.39e-2)" "unprognostic (6.97e-2)" "unprognostic (9.58e-2)" "unprognostic (4.69e-2)" "unprognostic (1.93e-1)" "unprognostic (1.46e-2)" "unprognostic (3.34e-1)" "unprognostic (4.38e-2)" "unprognostic (1.21e-1)" "unprognostic (5.26e-3)" "unprognostic (1.91e-2)" CTLA4 "CD, CD152, CELIAC3, CTLA-4, GSE, IDDM12" ENSG00000163599 "Cytotoxic T-lymphocyte associated protein 4" P16410 2 203853888-203873965 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Diabetes mellitus, Disease variant, FDA approved drug targets, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "lymphoid tissue: 35.1" "Cell type enriched" "Detected in some" 9 "T-cells: 87.4" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 3.8;ependymal cell: 1.5;leukocyte: 3.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in some" 7 "T-reg: 42.6" "Lineage enriched" "Detected in single" 427 "T-cells: 42.6" "Cancer enhanced" "Detected in some" "cervical cancer: 8.2;skin cancer: 5.6" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Kidney - T-cells, Minor Salivary Gland - T-cells, Prostate - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 39: Astrocytes - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 9: T-cells - Adaptive immunity: Regulation" 13 "unprognostic (2.09e-2)" "unprognostic (1.53e-2)" "unprognostic (2.29e-2)" "unprognostic (4.53e-2)" "unprognostic (7.26e-2)" "unprognostic (2.10e-1)" "unprognostic (1.92e-2)" "potential prognostic favorable (1.13e-4)" "potential prognostic unfavorable (2.59e-4)" "unprognostic (3.43e-1)" "unprognostic (4.87e-2)" "unprognostic (1.81e-2)" "unprognostic (1.83e-1)" "unprognostic (1.11e-1)" "unprognostic (4.10e-2)" "unprognostic (3.80e-1)" "unprognostic (9.07e-3)" "unprognostic (1.64e-1)" "unprognostic (1.31e-2)" "potential prognostic favorable (8.73e-4)" "unprognostic (1.12e-2)" "unprognostic (1.79e-1)" "unprognostic (1.86e-1)" "unprognostic (3.70e-1)" CTNNA1 CAP102 ENSG00000044115 "Catenin alpha 1" P35221 5 138610967-138935034 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1095.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB021089, HPA046119, HPA063535" Supported Supported "Golgi apparatus,Vesicles,Plasma membrane,Cell Junctions,Connecting piece,Mid piece,Principal piece" NA NA 41000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 51: Secretory epithelial cells - Mixed function" 73 "Plasma membrane, Cell Junctions" "Golgi apparatus, Vesicles, Connecting piece, Mid piece, Principal piece" "CAB021089: , HPA046119: , HPA063535: " "unprognostic (9.90e-2)" "unprognostic (7.56e-2)" "unprognostic (4.19e-1)" "unprognostic (1.99e-2)" "unprognostic (5.48e-3)" "unprognostic (9.48e-2)" "unprognostic (8.35e-2)" "potential prognostic unfavorable (2.84e-8)" "unprognostic (1.74e-2)" "unprognostic (7.22e-3)" "potential prognostic favorable (3.83e-8)" "unprognostic (4.99e-3)" "unprognostic (8.96e-2)" "unprognostic (3.40e-3)" "unprognostic (6.43e-2)" "unprognostic (1.02e-2)" "unprognostic (1.69e-2)" "unprognostic (2.57e-2)" "unprognostic (1.24e-1)" "unprognostic (1.12e-1)" "unprognostic (1.21e-2)" "potential prognostic unfavorable (2.44e-4)" "unprognostic (9.23e-2)" "unprognostic (2.83e-1)" "unprognostic (1.06e-1)" "unprognostic (3.80e-2)" "unprognostic (2.13e-1)" "unprognostic (3.76e-1)" "unprognostic (1.76e-1)" "unprognostic (2.08e-1)" "unprognostic (1.13e-1)" CTNNA2 "CAP-R, CT114" ENSG00000066032 "Catenin alpha 2" P26232 2 79185231-80648861 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Differentiation" "Developmental protein" "Disease variant, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 88.2;epididymis: 63.3;retina: 74.5" "Cell type enhanced" "Detected in many" "Astrocytes: 4909.1;Brain excitatory neurons: 1496.6;Brain inhibitory neurons: 1505.5;Ependymal cells: 2811.9;Lactotrophs: 1020.6;Müller glia: 3578.2;Oligodendrocyte progenitor cells: 1929.3;Other brain neurons: 1832.8;Pituitary stem cells: 1217.0;Retinal ganglion cells: 1263.1;Sertoli cells: 1950.8;Somatotrophs: 1078.2;Thyrotrophs: 1652.5" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Glioblastoma Multiforme (TCGA): 42.1;Kidney Chromophobe (TCGA): 11.6;Uterine Corpus Endometrial Carcinoma (TCGA): 11.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 96 "basophil: 55.7" "Lineage enriched" "Detected in single" 558 "granulocytes: 55.7" "Group enriched" "Detected in many" 4 "cervical cancer: 7.4;Myeloma: 8.7;Neuroblastoma: 23.0" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB037175 Enhanced NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 28: Astrocytes - Homeostasis & neuron support" 8 "CAB037175: " "unprognostic (1.15e-1)" "unprognostic (2.12e-2)" "unprognostic (1.40e-1)" "unprognostic (7.22e-2)" "unprognostic (9.17e-2)" "unprognostic (1.40e-1)" "unprognostic (9.94e-2)" "unprognostic (2.24e-1)" "unprognostic (1.60e-1)" "unprognostic (6.17e-2)" "unprognostic (1.31e-1)" "unprognostic (4.73e-2)" "unprognostic (3.78e-2)" "unprognostic (5.68e-2)" CTNNA3 "MGC26194, VR22" ENSG00000183230 "Catenin alpha 3" Q9UI47 10 65912457-67763637 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell adhesion" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 13.7;tongue: 14.0" "Group enriched" "Detected in many" 5 "Bergmann glia: 2992.1;Cardiomyocytes: 3863.2;Myonuclei: 5423.3;Oligodendrocytes: 5017.4" "Cell type enhanced" "Detected in all" "Bergmann glia: 2815.9;oligodendrocyte: 7394.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Smooth muscle cells, Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA061818 Enhanced NA NA "Cluster 41: Striated muscle - Muscle contraction" "Cluster 11: White matter - Signal transduction" "Cluster 5: Rhabdoid - Unknown function" "Cluster 55: Myocytes - Oxidative muscle function" 16 "HPA061818: " "unprognostic (4.95e-3)" "unprognostic (3.29e-2)" "potential prognostic favorable (8.70e-5)" "unprognostic (3.60e-1)" CTNNAL1 "alpha-CATU, CLLP" ENSG00000119326 "Catenin alpha like 1" Q9UBT7 9 108942569-109013522 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 273.5" "Cell type enhanced" "Detected in all" "Adrenal cortex cells: 759.3;Endometrial glandular cells: 358.9;Epididymal basal cells: 407.6;Esophageal apical cells: 405.9;Retinal pigment epithelial cells: 439.1;Schwann cells: 576.8;Sertoli cells: 356.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Thyroid Carcinoma (TCGA): 129.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 6.5" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 364.9" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 18: Adrenal cortex cells - Steroidogensis" 24 "unprognostic (2.56e-1)" "unprognostic (3.46e-2)" "unprognostic (1.12e-1)" "unprognostic (4.00e-1)" "unprognostic (1.91e-1)" "unprognostic (3.41e-2)" "unprognostic (1.13e-1)" "unprognostic (6.52e-2)" "unprognostic (8.25e-3)" "unprognostic (7.91e-2)" "unprognostic (3.08e-2)" "unprognostic (2.74e-1)" "unprognostic (1.65e-1)" "unprognostic (6.46e-3)" "potential prognostic unfavorable (1.57e-6)" "unprognostic (9.68e-2)" "unprognostic (3.74e-2)" "unprognostic (8.14e-2)" "unprognostic (2.97e-2)" "unprognostic (9.40e-2)" "unprognostic (1.17e-1)" "unprognostic (5.85e-2)" "unprognostic (3.82e-2)" "unprognostic (3.54e-2)" "unprognostic (3.65e-2)" "unprognostic (7.21e-2)" "unprognostic (1.37e-1)" "potential prognostic unfavorable (3.67e-4)" "unprognostic (3.02e-1)" "unprognostic (9.06e-3)" "unprognostic (6.87e-3)" CTNNB1 "armadillo, beta-catenin, CTNNB" ENSG00000168036 "Catenin beta 1" P35222 3 41194741-41260096 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Host-virus interaction, Neurogenesis, Transcription, Transcription regulation, Wnt signaling pathway" Activator "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 871.7" "Cell type enhanced" "Detected in all" "endothelial cell: 823.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000108, CAB001950, HPA029159, HPA029160" Supported Enhanced "Plasma membrane,Cell Junctions,Primary cilium,Basal body" NA NA 3200000 "Cluster 33: Non-specific - ATP binding" "Cluster 75: Ovary - Mixed function" "Cluster 44: Non-specific - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 443 "Plasma membrane" "Cell Junctions, Primary cilium, Basal body" "CAB000108: , CAB001950: , HPA029159: , HPA029160: " "unprognostic (1.79e-2)" "unprognostic (8.56e-2)" "unprognostic (1.15e-1)" "unprognostic (5.61e-3)" "unprognostic (3.56e-2)" "unprognostic (3.47e-1)" "unprognostic (1.20e-1)" "unprognostic (5.18e-2)" "unprognostic (3.77e-2)" "potential prognostic unfavorable (4.23e-4)" "validated prognostic favorable (6.88e-8)" "validated prognostic favorable (1.81e-5)" "unprognostic (3.52e-2)" "potential prognostic unfavorable (6.51e-4)" "unprognostic (1.47e-2)" "unprognostic (2.35e-1)" "unprognostic (1.78e-2)" "unprognostic (1.00e-1)" "unprognostic (2.01e-1)" "unprognostic (4.61e-2)" "unprognostic (8.64e-3)" "unprognostic (1.26e-2)" "unprognostic (2.00e-1)" "unprognostic (1.63e-1)" "unprognostic (3.63e-3)" "unprognostic (8.27e-2)" "unprognostic (2.22e-1)" "unprognostic (7.32e-3)" "unprognostic (2.73e-1)" "unprognostic (1.60e-1)" "unprognostic (4.10e-3)" CTNNBIP1 "ICAT, MGC15093" ENSG00000178585 "Catenin beta interacting protein 1" Q9NSA3 1 9848276-9910336 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 168.6;skin 1: 410.4" "Group enriched" "Detected in many" 5 "Esophageal apical cells: 3781.6;Esophageal suprabasal cells: 1436.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 13.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Heart muscle - Cardiomyocytes, Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Prostate glandular cells, Skin - Keratinocyte (granular), Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067089 Enhanced Approved Nucleoplasm,Cytosol NA NA 12000 "Cluster 45: Eosinophils - Unknown function" "Cluster 37: Skin - Keratinization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 23 "Nucleoplasm, Cytosol" "HPA067089: " "unprognostic (5.60e-3)" "unprognostic (1.61e-1)" "unprognostic (4.11e-1)" "unprognostic (1.37e-1)" "unprognostic (2.00e-3)" "unprognostic (1.31e-1)" "unprognostic (3.71e-1)" "unprognostic (2.13e-2)" "unprognostic (3.60e-2)" "unprognostic (1.15e-1)" "potential prognostic favorable (8.90e-8)" "unprognostic (1.73e-2)" "unprognostic (1.17e-2)" "validated prognostic unfavorable (3.04e-4)" "validated prognostic unfavorable (4.50e-5)" "unprognostic (2.39e-2)" "unprognostic (2.04e-2)" "unprognostic (1.92e-2)" "unprognostic (3.87e-2)" "unprognostic (8.81e-2)" "unprognostic (2.11e-1)" "unprognostic (1.47e-2)" "unprognostic (3.93e-2)" "unprognostic (1.46e-1)" "unprognostic (3.68e-1)" "unprognostic (1.17e-1)" "unprognostic (4.42e-2)" "unprognostic (1.56e-2)" "unprognostic (3.69e-2)" "unprognostic (5.71e-2)" "unprognostic (1.07e-2)" CTNNBL1 "C20orf33, FLJ21108, NAP, NYD-SP19, P14, P14L" ENSG00000132792 "Catenin beta like 1" Q8WYA6 20 37693955-37872129 "Cancer-related genes, Disease related genes, Essential proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity, mRNA processing, mRNA splicing" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 410.9;Late primary spermatocytes: 279.0;Mast cells: 513.8;Megakaryocyte-Erythroid progenitors: 461.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004742, HPA027906, HPA027907" Approved Supported Nucleoplasm,Centrosome,Cytosol No No "Cluster 41: Basophils - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 35: RS4;11 - Unknown function" "Cluster 58: Mast cells - Allergic inflammatory responses" 60 Nucleoplasm "Centrosome, Cytosol" "HPA004742: , HPA027906: , HPA027907: " "unprognostic (1.20e-1)" "unprognostic (4.18e-2)" "unprognostic (1.13e-1)" "unprognostic (1.09e-1)" "unprognostic (1.16e-1)" "unprognostic (1.30e-2)" "unprognostic (3.50e-1)" "unprognostic (1.76e-3)" "unprognostic (3.41e-2)" "unprognostic (4.27e-3)" "potential prognostic favorable (4.07e-4)" "unprognostic (5.73e-3)" "unprognostic (2.20e-1)" "unprognostic (2.00e-3)" "unprognostic (6.22e-2)" "unprognostic (3.03e-2)" "unprognostic (1.77e-2)" "unprognostic (2.34e-2)" "unprognostic (3.64e-1)" "unprognostic (1.23e-2)" "unprognostic (2.86e-2)" "unprognostic (4.42e-3)" "unprognostic (4.07e-2)" "unprognostic (1.22e-2)" "unprognostic (1.95e-1)" "unprognostic (1.15e-3)" "unprognostic (2.95e-1)" "unprognostic (3.32e-1)" "unprognostic (1.36e-1)" "unprognostic (4.55e-1)" "unprognostic (3.76e-1)" CTNND1 "CTNND, KIAA0384, p120, p120cas, p120ctn" ENSG00000198561 "Catenin delta 1" O60716 11 57753243-57819546 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Cell adhesion, Transcription, Transcription regulation, Wnt signaling pathway" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 113.4;Esophageal apical cells: 103.4;Foveolar cells: 138.5;Microglia: 134.0;Papillary tip epithelial cells: 128.0;Podocytes: 142.5;Renal collecting duct intercalated cells: 120.6;Renal collecting duct principal cells: 105.3;Renal connecting tubule cells: 105.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 4.8;intermediate monocyte: 9.4;myeloid DC: 6.4;non-classical monocyte: 5.8" "Group enriched" "Detected in many" 19 "dendritic cells: 6.4;monocytes: 9.4" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adrenal gland - Adrenal cortex cells, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other), Spleen - Endothelial cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003837, HPA015954, HPA015955" Enhanced Enhanced "Plasma membrane,Basal body" NA NA 20000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 8: Immune cells - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 102: Non-specific - Mixed function" 67 "Plasma membrane" "Basal body" "CAB003837: , HPA015954: , HPA015955: " "unprognostic (1.97e-1)" "unprognostic (2.00e-2)" "unprognostic (9.18e-2)" "unprognostic (1.02e-2)" "unprognostic (5.64e-2)" "unprognostic (2.10e-1)" "unprognostic (6.01e-2)" "unprognostic (2.52e-1)" "unprognostic (3.83e-1)" "unprognostic (1.05e-1)" "validated prognostic favorable (2.97e-9)" "validated prognostic favorable (8.63e-5)" "unprognostic (2.37e-1)" "unprognostic (1.85e-3)" "unprognostic (9.42e-2)" "unprognostic (1.31e-2)" "unprognostic (1.45e-2)" "unprognostic (1.49e-1)" "unprognostic (6.43e-2)" "unprognostic (3.41e-1)" "potential prognostic unfavorable (1.25e-5)" "potential prognostic unfavorable (9.04e-6)" "unprognostic (1.58e-1)" "unprognostic (1.21e-1)" "unprognostic (2.22e-3)" "unprognostic (1.97e-1)" "unprognostic (3.76e-1)" "unprognostic (8.77e-2)" "unprognostic (1.76e-1)" "unprognostic (3.24e-1)" "unprognostic (3.34e-1)" CTNND2 "GT24, NPRAP" ENSG00000169862 "Catenin delta 2" Q9UQB3 5 10971836-11904446 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell adhesion, Transcription, Transcription regulation, Wnt signaling pathway" "Developmental protein" "Autism, Autism spectrum disorder, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 72.2" "Cell type enhanced" "Detected in many" "Astrocytes: 4013.2;Bergmann glia: 3618.1;Brain excitatory neurons: 1243.8;Brain inhibitory neurons: 1098.2;Choroid plexus epithelial cells: 945.3;Lactotrophs: 776.6;Oligodendrocyte progenitor cells: 2053.7;Oligodendrocytes: 920.0;Other brain neurons: 880.8;Pituicytes/FSCs: 1102.3;Retinal amacrine cells: 856.5;Retinal ganglion cells: 726.2;Somatotrophs: 1227.7;Thyrotrophs: 911.6" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 16 "Glioblastoma Multiforme (TCGA): 58.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 5.3" "Adrenal gland - Adrenal medulla cells, Breast - Breast glandular cells, Lung - Alveolar cells type 1, Prostate - Prostate glandular cells, Skin - Outer root sheath cells, Spleen - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015077, CAB037339, HPA071124" Enhanced Approved "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 39: Astrocytes - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 28: Astrocytes - Homeostasis & neuron support" 4 "Nucleoplasm, Cell Junctions" Cytosol "CAB037339: , HPA015077: , HPA071124: " "unprognostic (1.24e-1)" "unprognostic (1.12e-2)" "unprognostic (2.49e-1)" "unprognostic (1.32e-1)" "unprognostic (1.88e-1)" "unprognostic (3.78e-2)" "unprognostic (1.41e-2)" "unprognostic (1.53e-2)" "unprognostic (1.44e-2)" "unprognostic (9.28e-2)" "unprognostic (3.30e-2)" "unprognostic (2.88e-2)" "unprognostic (6.65e-2)" CTNS "CTNS-LSB, PQLC4, SLC66A4" ENSG00000040531 "Cystinosin, lysosomal cystine transporter" O60931 17 3636459-3663103 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Melanin biosynthesis, Protein transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 100.7;Epicardial cells: 104.6;Platelets: 134.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 34.3;granulocytes: 28.2;monocytes: 10.5" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074687 Supported Vesicles NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 21: Testis - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 50: Lymphoma - Unknown function" "Cluster 47: Platelets - Hemostasis" Vesicles "HPA074687: " "unprognostic (4.29e-2)" "unprognostic (5.53e-2)" "unprognostic (4.49e-2)" "unprognostic (2.60e-2)" "unprognostic (4.03e-2)" "unprognostic (3.30e-1)" "unprognostic (4.12e-2)" "unprognostic (3.41e-2)" "unprognostic (2.48e-3)" "unprognostic (1.23e-1)" "unprognostic (2.03e-2)" "unprognostic (1.28e-2)" "unprognostic (3.10e-1)" "unprognostic (2.42e-3)" "unprognostic (1.64e-1)" "unprognostic (6.69e-2)" "unprognostic (1.35e-1)" "unprognostic (9.56e-3)" "unprognostic (1.12e-1)" "unprognostic (1.14e-1)" "unprognostic (4.72e-1)" "unprognostic (1.36e-3)" "unprognostic (2.16e-1)" "unprognostic (1.90e-2)" "unprognostic (1.03e-1)" "unprognostic (3.41e-2)" "unprognostic (1.18e-1)" "unprognostic (1.71e-1)" "unprognostic (2.69e-1)" "unprognostic (2.22e-1)" "unprognostic (7.81e-2)" CTPS1 "CTPS, GATD5A" ENSG00000171793 "CTP synthase 1" P17812 1 40979300-41012565 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Immunity, Pyrimidine biosynthesis" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 92.3;Salivary acinar cells: 80.4;Smooth muscle cells: 94.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in all" 7 "Adrenocortical cancer: 588.4" "Prostate - Smooth muscle cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017111, HPA051322" Enhanced Approved "Actin filaments,Cytosol" NA Yes 100000 "Cluster 13: Non-specific - Mitochondria" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 23: Choroid plexus - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 62: Smooth muscle cells - Muscle contraction" 24 Cytosol "Actin filaments" "CAB017111: , HPA051322: " "unprognostic (3.80e-2)" "unprognostic (1.19e-2)" "unprognostic (2.03e-1)" "potential prognostic favorable (1.28e-4)" "unprognostic (1.90e-1)" "unprognostic (1.98e-1)" "unprognostic (1.98e-3)" "unprognostic (6.10e-2)" "unprognostic (1.67e-1)" "potential prognostic favorable (2.19e-4)" "unprognostic (2.86e-1)" "unprognostic (6.13e-2)" "unprognostic (2.62e-2)" "potential prognostic unfavorable (5.99e-4)" "unprognostic (2.75e-1)" "unprognostic (2.08e-2)" "unprognostic (4.11e-1)" "unprognostic (2.11e-1)" "unprognostic (7.24e-2)" "unprognostic (3.09e-2)" "unprognostic (3.04e-1)" "unprognostic (1.13e-1)" "unprognostic (1.68e-1)" "unprognostic (1.09e-2)" "unprognostic (2.10e-2)" "unprognostic (9.72e-2)" "unprognostic (6.77e-2)" "unprognostic (1.70e-1)" "unprognostic (3.23e-2)" CTPS2 GATD5B ENSG00000047230 "CTP synthase 2" Q9NRF8 X 16587999-16712936 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Pyrimidine biosynthesis" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017437, HPA075930" Approved Approved Mitochondria,Cytosol NA NA 30000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 36: Non-specific - mRNA processing" "Cluster 7: Non-specific - Transcription" 40 "Mitochondria, Cytosol" "HPA017437: , HPA075930: " "unprognostic (2.16e-1)" "unprognostic (1.04e-2)" "unprognostic (1.14e-1)" "unprognostic (1.56e-1)" "unprognostic (2.04e-1)" "unprognostic (7.16e-2)" "unprognostic (1.31e-1)" "unprognostic (5.44e-2)" "unprognostic (1.28e-1)" "unprognostic (3.79e-1)" "unprognostic (1.96e-3)" "unprognostic (2.78e-3)" "unprognostic (2.11e-1)" "potential prognostic unfavorable (1.62e-5)" "unprognostic (3.08e-2)" "unprognostic (8.15e-2)" "unprognostic (7.15e-2)" "unprognostic (5.19e-3)" "unprognostic (1.30e-1)" "unprognostic (8.97e-2)" "unprognostic (2.31e-1)" "unprognostic (2.30e-2)" "unprognostic (2.97e-1)" "unprognostic (1.27e-2)" "unprognostic (7.62e-3)" "unprognostic (5.37e-2)" "unprognostic (2.61e-2)" "unprognostic (4.35e-1)" "unprognostic (2.53e-1)" "unprognostic (1.46e-2)" "unprognostic (1.59e-1)" CTR9 "KIAA0155, p150TSP, SH2BP1, TSBP" ENSG00000198730 "CTR9 homolog, Paf1/RNA polymerase II complex component" Q6PD62 11 10751246-10801625 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA061027, HPA068122" Supported Enhanced Nucleoplasm No No "Cluster 42: Non-specific - Vesicular transport" "Cluster 22: Epididymis - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 24: Non-specific - Unknown function" "Cluster 26: Keratinocytes - Keratinization" 73 Nucleoplasm "HPA061027: , HPA068122: " "unprognostic (1.12e-1)" "unprognostic (1.10e-1)" "unprognostic (2.52e-2)" "unprognostic (5.15e-3)" "unprognostic (2.98e-1)" "unprognostic (8.40e-3)" "unprognostic (4.74e-2)" "potential prognostic unfavorable (3.17e-4)" "unprognostic (3.69e-1)" "potential prognostic unfavorable (3.20e-4)" "validated prognostic favorable (1.86e-7)" "validated prognostic favorable (2.73e-4)" "unprognostic (1.40e-1)" "unprognostic (7.92e-2)" "unprognostic (2.19e-2)" "unprognostic (3.15e-1)" "unprognostic (4.19e-2)" "unprognostic (1.88e-1)" "unprognostic (1.16e-1)" "unprognostic (1.34e-1)" "potential prognostic unfavorable (9.15e-4)" "unprognostic (2.78e-2)" "unprognostic (6.02e-3)" "unprognostic (3.21e-2)" "unprognostic (1.60e-2)" "unprognostic (1.78e-2)" "unprognostic (2.02e-1)" "unprognostic (8.17e-2)" "unprognostic (2.87e-1)" "unprognostic (2.72e-1)" "unprognostic (1.36e-1)" CTRB1 CTRB ENSG00000168925 "Chymotrypsinogen B1" P17538 16 75218988-75226338 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5352 "pancreas: 126232.8" "Cell type enriched" "Detected in some" 509 "Pancreatic acinar cells: 32624.3" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 2302 "Pancreatic Adenocarcinoma (TCGA): 3062.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to digestive system" Enzyme NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 15: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 5: Pancreatic acinar cells - Pancreatic exocrine secretion" 1 "unprognostic (2.33e-1)" "unprognostic (4.42e-3)" "unprognostic (3.79e-1)" CTRB2 ENSG00000168928 "Chymotrypsinogen B2" Q6GPI1 16 75204103-75207161 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 2546 "pancreas: 94683.3" "Cell type enriched" "Detected in some" 104 "Pancreatic acinar cells: 56577.7" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 2928 "Pancreatic Adenocarcinoma (TCGA): 3934.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to digestive system" Enzyme NA NA 3300000 "Cluster 8: Pancreas - Proteolysis" "Cluster 15: Kidney cancer - Membrane components" "Cluster 5: Pancreatic acinar cells - Pancreatic exocrine secretion" "unprognostic (2.63e-2)" "unprognostic (2.07e-3)" "unprognostic (2.25e-1)" CTRC "CLCR, ELA4" ENSG00000162438 "Chymotrypsin C" Q99895 1 15438442-15449242 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5525 "pancreas: 12512.5" "Cell type enriched" "Detected in some" 232 "Pancreatic acinar cells: 27400.4" "Cell type enhanced" "Detected in single" "upper rhombic lip: 1.0" "Cancer enriched" "Detected in some" 104 "Pancreatic Adenocarcinoma (TCGA): 166.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Exocrine glandular cells" "Not detected" "Not detected" HPA046920 Enhanced "Secreted to digestive system" Enzyme NA NA 86000 "Cluster 8: Pancreas - Proteolysis" "Cluster 48: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 5: Pancreatic acinar cells - Pancreatic exocrine secretion" 13 "HPA046920: " "unprognostic (2.21e-1)" "unprognostic (2.52e-1)" "unprognostic (7.54e-3)" "unprognostic (6.32e-2)" CTRL ENSG00000141086 "Chymotrypsin like" P40313 16 67927640-67932365 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1212 "pancreas: 7054.0" "Cell type enhanced" "Detected in some" "Adipocytes: 3.0;Astrocytes: 3.9;Bergmann glia: 6.5;Cardiomyocytes: 19.8;Epicardial cells: 4.5;Pancreatic acinar cells: 7.9" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in some" 49 "Pancreatic Adenocarcinoma (TCGA): 105.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Pancreas - Exocrine glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA034504, HPA034505" Enhanced "Secreted to digestive system" Enzyme NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 6: Non-specific - Immune response" "Cluster 35: RS4;11 - Unknown function" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 5 "HPA034504: , HPA034505: " "unprognostic (8.83e-3)" "unprognostic (2.75e-2)" "unprognostic (3.27e-2)" "unprognostic (1.29e-1)" "unprognostic (1.55e-1)" "unprognostic (2.74e-2)" "unprognostic (2.63e-2)" "unprognostic (3.88e-2)" CTSA "GSL, PPGB" ENSG00000064601 "Cathepsin A" P10619 20 45890144-45898949 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 312.4" "Cell type enriched" "Detected in all" 6 "Platelets: 2264.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB024930, HPA031068, HPA072487" Enhanced Enhanced Vesicles "Intracellular and membrane" Enzyme NA NA 31000000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 62: Non-specific - Plasma proteins" "Cluster 47: Platelets - Hemostasis" 13 Vesicles "CAB024930: , HPA031068: , HPA072487: " "unprognostic (2.70e-1)" "potential prognostic unfavorable (9.10e-4)" "unprognostic (5.61e-2)" "unprognostic (1.48e-1)" "unprognostic (2.57e-1)" "unprognostic (6.46e-2)" "unprognostic (8.79e-2)" "unprognostic (2.60e-2)" "unprognostic (8.34e-2)" "unprognostic (9.60e-2)" "unprognostic (4.47e-3)" "unprognostic (6.59e-3)" "unprognostic (4.17e-1)" "potential prognostic unfavorable (1.96e-6)" "unprognostic (2.38e-2)" "unprognostic (1.06e-1)" "unprognostic (5.55e-2)" "unprognostic (1.47e-2)" "unprognostic (7.50e-3)" "unprognostic (2.36e-2)" "unprognostic (3.57e-2)" "unprognostic (2.55e-1)" "unprognostic (2.65e-1)" "unprognostic (1.57e-1)" "unprognostic (2.91e-1)" "unprognostic (3.80e-2)" "unprognostic (1.51e-2)" "unprognostic (1.28e-1)" "unprognostic (2.17e-2)" "unprognostic (6.29e-2)" "unprognostic (3.30e-3)" CTSB ENSG00000164733 "Cathepsin B" P07858 8 11842524-11869533 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 991.2" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 409.7;Hofbauer cells: 627.2;Kupffer cells: 1672.7;Macrophages: 437.5;Microglia: 369.8;monocytes: 390.0;Syncytiotrophoblasts: 298.2" "Cell type enriched" "Detected in all" 6 "central nervous system macrophage: 499.5" "Cancer enriched" "Detected in all" 4 "Thyroid Carcinoma (TCGA): 2281.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 389.7;classical monocyte: 610.5;intermediate monocyte: 467.6;myeloid DC: 287.7;non-classical monocyte: 309.1;plasmacytoid DC: 410.8" "Group enriched" "Detected in all" 6 "dendritic cells: 410.8;granulocytes: 389.7;monocytes: 610.5" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Proximal tubular cells, Lung - Macrophages, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000457, HPA018156, HPA048998" Enhanced Supported Nucleoli,Vesicles "Secreted to blood" Enzyme NA NA 524000000 42000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 74 Vesicles Nucleoli "CAB000457: , HPA018156: , HPA048998: " "unprognostic (4.69e-2)" "unprognostic (3.48e-2)" "unprognostic (1.64e-1)" "unprognostic (1.48e-2)" "unprognostic (1.04e-1)" "unprognostic (1.73e-1)" "potential prognostic unfavorable (1.14e-4)" "unprognostic (2.58e-3)" "unprognostic (2.18e-1)" "potential prognostic unfavorable (1.72e-4)" "potential prognostic favorable (1.04e-5)" "unprognostic (1.69e-2)" "unprognostic (7.41e-3)" "unprognostic (1.16e-1)" "unprognostic (1.04e-1)" "unprognostic (2.12e-1)" "unprognostic (2.36e-3)" "unprognostic (5.03e-2)" "unprognostic (2.92e-2)" "unprognostic (1.63e-1)" "potential prognostic unfavorable (6.03e-4)" "unprognostic (1.18e-2)" "unprognostic (1.89e-1)" "unprognostic (7.61e-2)" "unprognostic (5.33e-2)" "unprognostic (2.65e-2)" "unprognostic (2.62e-1)" "unprognostic (2.65e-1)" "unprognostic (7.41e-2)" "unprognostic (4.70e-2)" "unprognostic (5.08e-2)" CTSC "DPP1, PALS, PLS" ENSG00000109861 "Cathepsin C" P53634 11 88265069-88359684 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Thiol protease" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 535.3;Decidual stromal cells: 477.4;Hofbauer cells: 2040.8;Kupffer cells: 597.5;Macrophages: 530.8;pDCs: 544.2;Respiratory secretory cells: 627.1" "Group enriched" "Detected in many" 4 "central nervous system macrophage: 259.7;leukocyte: 161.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Macrophages, Lung - Macrophages, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025364, HPA066610, HPA068434" Enhanced Supported Vesicles "Intracellular and membrane" Enzyme No No 12000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 9 Vesicles "CAB025364: , HPA066610: , HPA068434: " "potential prognostic unfavorable (1.04e-5)" "unprognostic (1.63e-1)" "unprognostic (2.16e-1)" "unprognostic (2.16e-1)" "unprognostic (5.51e-2)" "unprognostic (1.93e-1)" "unprognostic (4.28e-3)" "unprognostic (9.27e-2)" "unprognostic (7.25e-3)" "unprognostic (4.08e-3)" "unprognostic (7.67e-3)" "unprognostic (2.92e-2)" "unprognostic (8.80e-2)" "potential prognostic unfavorable (6.04e-5)" "unprognostic (7.66e-3)" "unprognostic (2.28e-2)" "unprognostic (2.43e-2)" "unprognostic (2.46e-1)" "unprognostic (1.35e-1)" "unprognostic (4.46e-2)" "unprognostic (1.21e-1)" "unprognostic (3.96e-2)" "unprognostic (1.73e-1)" "unprognostic (3.55e-1)" "unprognostic (7.26e-2)" "unprognostic (4.89e-2)" "unprognostic (1.31e-1)" "unprognostic (3.31e-1)" "unprognostic (2.06e-1)" "unprognostic (1.52e-1)" "unprognostic (1.44e-1)" CTSD "CLN10, CPSD" ENSG00000117984 "Cathepsin D" P07339 11 1752752-1764573 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Aspartyl protease, Hydrolase, Protease" "Alzheimer disease, Cancer-related genes, Disease variant, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 14.6;Enterocytes: 19.7;Fallopian tube ciliated cells: 15.4;Prostatic hillock cells: 13.6;Retinal pigment epithelial cells: 55.4;Salivary duct cells: 17.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Adrenal cortex cells, Lung - Macrophages, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000109, HPA003001" Supported "Secreted to blood" Enzyme NA NA 760000000 140000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 28: Liver & Adrenal gland - Secretion" "Cluster 21: Non-specific - Metabolism" "Cluster 15: Kidney cancer - Membrane components" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 38 "CAB000109: , HPA003001: " "unprognostic (2.67e-1)" "unprognostic (6.10e-2)" "unprognostic (4.59e-2)" "unprognostic (4.02e-2)" "unprognostic (2.58e-1)" "unprognostic (6.58e-2)" "potential prognostic unfavorable (5.03e-4)" "unprognostic (2.53e-2)" "unprognostic (2.53e-1)" "unprognostic (3.86e-2)" "potential prognostic favorable (6.15e-9)" "unprognostic (1.77e-1)" "unprognostic (2.34e-3)" "unprognostic (1.64e-2)" "unprognostic (5.26e-2)" "unprognostic (6.97e-2)" "unprognostic (1.12e-1)" "unprognostic (2.98e-3)" "unprognostic (1.40e-1)" "unprognostic (9.43e-3)" "unprognostic (2.01e-1)" "unprognostic (8.89e-3)" "unprognostic (5.08e-2)" "unprognostic (3.20e-1)" "potential prognostic unfavorable (9.56e-5)" "unprognostic (5.04e-2)" "unprognostic (9.30e-2)" "unprognostic (1.50e-1)" "unprognostic (2.81e-2)" "unprognostic (4.25e-3)" "unprognostic (1.32e-1)" CTSE ENSG00000196188 "Cathepsin E" P14091 1 206008535-206023909 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "stomach 1: 1103.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 650.2;Alveolar cells type 2: 173.8;Foveolar cells: 1602.4;Gastric chief cells: 193.3;Gastric progenitor cells: 252.5;Mucous neck cells: 400.8;Parietal cells: 309.4;Transitional alveolar cells: 389.4" "Not detected" "Not detected" "Group enriched" "Detected in many" 8 "Lung Adenocarcinoma (TCGA): 199.0;Pancreatic Adenocarcinoma (TCGA): 534.7;Stomach Adenocarcinoma (TCGA): 336.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "colorectal cancer: 28.4;Esophageal cancer: 48.8;Gastric cancer: 110.7;pancreatic cancer: 35.3" "Colon - Colon enterocytes, Pituitary gland - Corticotropes, Spleen - Erythrocytes, Stomach - Gastric mucous cells" "Not detected" "Not detected" "HPA012674, HPA012940, CAB032687" Enhanced Approved Vesicles "Intracellular and membrane" Enzyme NA NA "Cluster 60: Stomach - Digestion" "Cluster 9: Non-specific - Receptor signaling" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 68: Foveolar cells - Mucosal defense" Vesicles "CAB032687: , HPA012674: , HPA012940: " "unprognostic (1.58e-2)" "unprognostic (1.79e-3)" "unprognostic (2.11e-2)" "unprognostic (8.09e-2)" "potential prognostic favorable (4.11e-4)" "unprognostic (6.07e-3)" "unprognostic (2.78e-1)" "unprognostic (6.06e-3)" "unprognostic (6.13e-3)" "unprognostic (2.48e-1)" "unprognostic (3.18e-1)" "unprognostic (2.67e-2)" "unprognostic (2.10e-1)" "unprognostic (6.88e-2)" "unprognostic (1.01e-1)" "unprognostic (8.20e-3)" "potential prognostic favorable (1.04e-4)" "unprognostic (8.33e-2)" "unprognostic (2.29e-1)" "unprognostic (6.99e-2)" "unprognostic (1.09e-1)" "unprognostic (3.56e-2)" "unprognostic (3.13e-1)" CTSF "CATSF, CLN13" ENSG00000174080 "Cathepsin F" Q9UBX1 11 66563464-66568879 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Disease variant, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 123.5" "Cell type enhanced" "Detected in many" "Early spermatids: 148.4;Late primary spermatocytes: 296.4;Late spermatids: 536.7;Melanocytes: 203.4;Müller glia: 175.7;Ovarian stromal cells: 145.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002141, HPA031431" Enhanced Supported "Endoplasmic reticulum,Vesicles,Plasma membrane" "Intracellular and membrane" Enzyme NA NA 8200000 "Cluster 27: T-cells - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 21: Non-specific - Metabolism" "Cluster 69: Skin cancer - ECM organization" "Cluster 108: Fibroblasts - ECM organization" Vesicles "Endoplasmic reticulum, Plasma membrane" "CAB002141: , HPA031431: " "unprognostic (1.10e-2)" "unprognostic (5.84e-3)" "unprognostic (3.86e-2)" "unprognostic (5.67e-3)" "unprognostic (6.23e-3)" "unprognostic (1.93e-1)" "potential prognostic unfavorable (5.00e-4)" "unprognostic (1.53e-2)" "unprognostic (1.48e-2)" "unprognostic (6.85e-3)" "unprognostic (6.83e-3)" "potential prognostic favorable (2.95e-4)" "unprognostic (1.26e-3)" "unprognostic (8.33e-2)" "unprognostic (1.02e-1)" "unprognostic (1.56e-2)" "unprognostic (1.22e-1)" "unprognostic (2.29e-1)" "unprognostic (8.61e-2)" "unprognostic (1.05e-1)" "unprognostic (1.60e-2)" "unprognostic (1.76e-1)" "unprognostic (1.24e-3)" "unprognostic (6.32e-2)" "unprognostic (1.25e-2)" "unprognostic (1.73e-2)" "unprognostic (3.08e-2)" "unprognostic (3.16e-2)" "unprognostic (1.64e-1)" "unprognostic (2.42e-1)" "unprognostic (1.23e-1)" CTSG CG ENSG00000100448 "Cathepsin G" P08311 14 24573518-24576250 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Chemotaxis "Antibiotic, Antimicrobial, Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 155 "bone marrow: 5049.0" "Group enriched" "Detected in some" 4 "Mast cells: 834.6;Neutrophil progenitors: 544.7" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in some" 430 "Leukemia: 517.5" "Adipose subcutaneous - Mast cells, Adipose visceral - Mast cells, Colon - Mast cells, Lung - Neutrophils_1, Minor Salivary Gland - Mast cells, Skeletal muscle - Fibroblasts, Spleen - Neutrophils_1, Stomach - Fibroblasts" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000110, HPA047737" Enhanced "Intracellular and membrane" Enzyme NA NA 3200000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 34 "CAB000110: , HPA047737: " "unprognostic (1.82e-1)" "unprognostic (2.49e-1)" "unprognostic (3.59e-2)" "unprognostic (1.03e-3)" "unprognostic (3.22e-1)" "unprognostic (2.88e-1)" "unprognostic (5.19e-3)" "unprognostic (1.75e-1)" "potential prognostic favorable (7.46e-7)" "unprognostic (1.03e-3)" "unprognostic (1.94e-1)" "unprognostic (5.24e-2)" "unprognostic (1.70e-2)" "potential prognostic favorable (6.96e-4)" "unprognostic (8.04e-2)" "unprognostic (1.78e-2)" "unprognostic (3.49e-2)" "unprognostic (4.70e-2)" "unprognostic (5.60e-3)" "unprognostic (8.46e-2)" "unprognostic (1.43e-3)" "unprognostic (8.75e-2)" "unprognostic (2.53e-2)" CTSH "ACC-4, ACC-5, ACC4, ACC5, CPSB" ENSG00000103811 "Cathepsin H" P09668 15 78921058-78949574 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 329.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 1745.4;cDC: 385.5;Cholangiocytes: 369.5;Decidual stromal cells: 364.9;Epididymal efferent duct absorptive cells: 765.6;Transitional alveolar cells: 507.9;Urothelial cells: 430.2" "Cell type enhanced" "Detected in all" "astrocyte: 68.3;Bergmann glia: 78.6;central nervous system macrophage: 99.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 209.6;intermediate monocyte: 138.1;memory B-cell: 83.8;myeloid DC: 184.0;naive B-cell: 56.3;non-classical monocyte: 95.3" "Group enriched" "Detected in all" 5 "B-cells: 83.8;dendritic cells: 184.0;monocytes: 209.6" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Alveolar cells type 2, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000458, HPA003524" Enhanced Supported "Vesicles,Cytosol,Cytoplasmic bodies" "Intracellular and membrane" Enzyme NA NA 6400000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 72: Kidney - Transmembrane transport" "Cluster 39: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 81: Alveolar cells - Lung function" 23 "Vesicles, Cytosol, Cytoplasmic bodies" "CAB000458: , HPA003524: " "potential prognostic favorable (2.93e-4)" "unprognostic (7.06e-2)" "unprognostic (7.41e-2)" "unprognostic (2.57e-3)" "unprognostic (2.86e-1)" "unprognostic (1.64e-2)" "unprognostic (1.43e-2)" "unprognostic (6.29e-2)" "unprognostic (3.45e-1)" "unprognostic (1.10e-2)" "unprognostic (6.09e-3)" "unprognostic (1.66e-1)" "unprognostic (2.75e-2)" "unprognostic (1.63e-2)" "unprognostic (1.31e-1)" "potential prognostic favorable (3.87e-4)" "unprognostic (9.75e-2)" "unprognostic (1.08e-1)" "unprognostic (2.69e-2)" "unprognostic (4.61e-2)" "unprognostic (1.17e-1)" "potential prognostic unfavorable (2.98e-4)" "unprognostic (3.59e-1)" "unprognostic (1.66e-1)" "unprognostic (3.15e-2)" "unprognostic (2.52e-2)" "unprognostic (1.61e-1)" "unprognostic (3.27e-1)" "unprognostic (2.59e-2)" "unprognostic (2.01e-2)" "unprognostic (1.34e-1)" CTSK "CTSO, CTSO2, PKND, PYCD" ENSG00000143387 "Cathepsin K" P43235 1 150794880-150809577 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Thiol protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 333.6" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 333.9;Fibroblasts: 347.6;Leydig cells: 93.6;Melanocytes: 95.4;Peritubular myoid cells: 135.5;Retinal pigment epithelial cells: 238.7" "Cell type enhanced" "Detected in all" "fibroblast: 46.2" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 16 "choroid plexus: 31.1" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.9" "Lineage enriched" "Detected in single" 5 "monocytes: 1.9" "Cancer enriched" "Detected in many" 5 "skin cancer: 65.3" "Adrenal gland - Fibroblasts, Breast - Fibroblasts, Heart muscle - Fibroblasts, Lung - Fibroblasts_2, Minor Salivary Gland - Macrophages, Prostate - Fibroblasts, Skin - Fibroblasts_2, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050346 Supported Vesicles "Intracellular and membrane" Enzyme NA NA 130000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 75: Ovary - Mixed function" "Cluster 36: Choroid plexus - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 4 Vesicles "HPA050346: " "unprognostic (5.10e-3)" "unprognostic (1.62e-1)" "unprognostic (9.90e-2)" "unprognostic (3.28e-2)" "unprognostic (1.93e-1)" "unprognostic (1.20e-1)" "potential prognostic unfavorable (6.99e-4)" "unprognostic (2.91e-1)" "unprognostic (8.55e-2)" "unprognostic (1.33e-1)" "unprognostic (6.33e-2)" "unprognostic (9.52e-2)" "unprognostic (1.12e-1)" "unprognostic (1.68e-2)" "unprognostic (1.01e-2)" "unprognostic (2.12e-1)" "unprognostic (1.49e-1)" "unprognostic (1.25e-1)" "unprognostic (1.63e-1)" "unprognostic (1.21e-2)" "potential prognostic unfavorable (2.18e-4)" "unprognostic (9.64e-2)" "unprognostic (3.82e-2)" "unprognostic (3.60e-2)" "unprognostic (4.60e-2)" "unprognostic (1.14e-2)" "unprognostic (3.16e-1)" "unprognostic (8.30e-3)" "unprognostic (2.05e-2)" "unprognostic (2.79e-3)" "unprognostic (1.06e-1)" CTSL "CTSL1, FLJ31037" ENSG00000135047 "Cathepsin L" P07711 9 87724051-87731469 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 529.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1155.5;Decidual stromal cells: 496.2;Extravillous trophoblasts: 1595.2;Hofbauer cells: 1183.9;Migrating cytotrophoblasts: 1229.4;Syncytiotrophoblasts: 1915.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "intermediate monocyte: 128.2;non-classical monocyte: 196.2" "Lineage enriched" "Detected in many" 12 "monocytes: 196.2" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Spleen - Macrophages, Testis - Spermatocytes" "Low region specificity" "Detected in all" "CAB000459, HPA070413" Enhanced Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" Enzyme NA NA 10000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 12: Non-specific - Vasculature" "Cluster 7: Liver cancer - Metabolism" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 50 "Golgi apparatus, Vesicles" "CAB000459: , HPA070413: " "unprognostic (6.87e-2)" "unprognostic (1.23e-1)" "unprognostic (3.13e-2)" "unprognostic (8.67e-2)" "unprognostic (1.13e-1)" "potential prognostic unfavorable (4.25e-7)" "unprognostic (1.00e-2)" "potential prognostic unfavorable (4.20e-4)" "unprognostic (5.48e-2)" "potential prognostic favorable (4.43e-11)" "unprognostic (3.87e-2)" "unprognostic (3.88e-3)" "unprognostic (9.57e-3)" "potential prognostic unfavorable (6.88e-5)" "unprognostic (2.50e-2)" "unprognostic (1.32e-2)" "unprognostic (4.48e-2)" "unprognostic (4.07e-2)" "unprognostic (1.50e-1)" "unprognostic (1.51e-1)" "unprognostic (3.08e-2)" "unprognostic (2.00e-1)" "unprognostic (4.20e-2)" "unprognostic (1.24e-1)" "unprognostic (2.02e-1)" "unprognostic (2.80e-2)" "unprognostic (3.14e-2)" "unprognostic (3.90e-2)" "unprognostic (1.84e-1)" CTSO CTSO1 ENSG00000256043 "Cathepsin O" P43234 4 155921580-155953912 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 23.8;Bergmann glia: 27.3;Ependymal cells: 19.3;Loop of henle epithelial cells: 17.6;Microglia: 18.8;Oligodendrocyte progenitor cells: 52.1;Oligodendrocytes: 16.1;Podocytes: 15.7;Proximal tubule cells: 11.9;Renal collecting duct intercalated cells: 10.2;Renal collecting duct principal cells: 14.0;Renal connecting tubule cells: 9.9" "Cell type enhanced" "Detected in many" "oligodendrocyte precursor cell: 60.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002041 Approved "Intracellular and membrane" Enzyme NA NA 37000 "Cluster 24: Non-specific - Transcription" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 9: Non-specific - Receptor signaling" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 4 "HPA002041: " "unprognostic (1.07e-1)" "unprognostic (4.76e-3)" "unprognostic (1.11e-1)" "unprognostic (8.66e-2)" "unprognostic (2.84e-1)" "unprognostic (2.42e-2)" "unprognostic (2.50e-2)" "unprognostic (3.17e-1)" "unprognostic (2.53e-1)" "unprognostic (3.48e-1)" "potential prognostic favorable (2.75e-7)" "unprognostic (5.88e-2)" "unprognostic (2.92e-1)" "unprognostic (2.92e-3)" "potential prognostic favorable (1.02e-4)" "unprognostic (9.50e-2)" "unprognostic (1.56e-1)" "unprognostic (7.52e-2)" "unprognostic (9.86e-3)" "unprognostic (1.23e-1)" "unprognostic (9.86e-2)" "unprognostic (1.17e-1)" "unprognostic (1.99e-1)" "unprognostic (3.55e-1)" "unprognostic (1.64e-1)" "unprognostic (1.31e-1)" "unprognostic (3.43e-1)" "unprognostic (3.54e-2)" "unprognostic (6.31e-2)" "unprognostic (2.87e-1)" "unprognostic (7.88e-2)" CTSS ENSG00000163131 "Cathepsin S" P25774 1 150730079-150765957 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 122.0;lymphoid tissue: 127.8" "Cell type enhanced" "Detected in many" "cDC: 622.1;Colonocytes: 484.0;Hofbauer cells: 519.0;Kupffer cells: 2998.9;Macrophages: 1043.0;Monocyte progenitors: 491.0;monocytes: 2663.4;Neutrophil progenitors: 828.5;Neutrophils: 1729.7" "Group enriched" "Detected in all" 8 "central nervous system macrophage: 216.3;leukocyte: 207.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 2462.4" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "lymphoma: 35.9;Myeloma: 33.2" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Minor Salivary Gland - Macrophages, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000460, HPA002988" Supported Approved Vesicles "Intracellular and membrane" Enzyme NA NA 14000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 75 Vesicles "CAB000460: , HPA002988: " "potential prognostic favorable (6.46e-4)" "unprognostic (8.77e-2)" "unprognostic (1.29e-1)" "unprognostic (2.69e-1)" "unprognostic (1.88e-2)" "potential prognostic favorable (8.56e-4)" "unprognostic (2.02e-1)" "unprognostic (2.09e-1)" "unprognostic (1.21e-2)" "unprognostic (6.03e-2)" "unprognostic (4.07e-3)" "unprognostic (7.60e-2)" "unprognostic (1.76e-1)" "unprognostic (9.41e-2)" "unprognostic (2.93e-2)" "unprognostic (5.98e-3)" "unprognostic (4.09e-2)" "potential prognostic unfavorable (5.83e-4)" "unprognostic (1.89e-1)" "unprognostic (4.18e-2)" "unprognostic (2.19e-1)" "unprognostic (6.76e-2)" "potential prognostic favorable (8.02e-4)" "unprognostic (1.01e-1)" "unprognostic (5.05e-2)" "unprognostic (9.37e-2)" "unprognostic (1.28e-1)" "unprognostic (8.13e-2)" "unprognostic (5.36e-2)" "unprognostic (2.36e-1)" "unprognostic (3.18e-1)" CTSV "CTSL2, CTSU" ENSG00000136943 "Cathepsin V" O60911 9 97029677-97156556 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "lymphoid tissue: 599.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 136.4;Esophageal apical cells: 614.8;Extravillous trophoblasts: 211.5;Medullary thymic epithelial cells: 650.5;Migrating cytotrophoblasts: 216.2;Ocular epithelial cells: 976.3;Sertoli cells: 249.2" "Cell type enhanced" "Detected in many" "eccentric medium spiny neuron: 5.5;oligodendrocyte: 4.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "plasmacytoid DC: 15.2" "Lineage enriched" "Detected in many" 4 "dendritic cells: 15.2" "Cancer enriched" "Detected in all" 7 "testis cancer: 681.3" "Kidney - Proximal tubular cells, Prostate - Prostate basal glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" CAB017112 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center,Plasma membrane,Cytosol" "Intracellular and membrane" Enzyme NA NA 300000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 80: Thymus - Adaptive immune response" "Cluster 9: Non-specific - Receptor signaling" "Cluster 34: Testis cancer - Unknown function" "Cluster 100: Stratified epithelial cells - Barrier functions" 27 "Nucleoli fibrillar center, Cytosol" "Nucleoplasm, Plasma membrane" "CAB017112: " "unprognostic (4.13e-3)" "unprognostic (2.90e-1)" "unprognostic (3.06e-2)" "unprognostic (3.64e-2)" "unprognostic (7.95e-2)" "unprognostic (1.28e-1)" "unprognostic (6.71e-3)" "unprognostic (1.24e-1)" "unprognostic (8.27e-3)" "unprognostic (3.13e-2)" "unprognostic (5.97e-2)" "potential prognostic unfavorable (5.59e-4)" "potential prognostic unfavorable (2.14e-4)" "unprognostic (2.60e-2)" "unprognostic (2.65e-2)" "unprognostic (3.11e-1)" "unprognostic (4.71e-2)" "unprognostic (1.76e-1)" "potential prognostic unfavorable (6.01e-4)" "unprognostic (2.85e-3)" "unprognostic (1.03e-2)" "unprognostic (1.24e-1)" "unprognostic (2.01e-1)" "unprognostic (1.93e-1)" "unprognostic (1.57e-2)" "unprognostic (1.74e-1)" "unprognostic (1.51e-3)" "unprognostic (6.63e-2)" CTSW ENSG00000172543 "Cathepsin W" P56202 11 65879809-65883741 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 109.6;lymphoid tissue: 40.0" "Cell type enhanced" "Detected in some" "Hematopoietic stem cells: 53.9;Innate lymphoid cells: 145.9;Megakaryocyte progenitors: 139.3;Megakaryocyte-Erythroid progenitors: 56.3;Megakaryocytes: 191.6;NK-cells: 455.0;Plasma cells: 78.1;Platelets: 293.7;T-cells: 191.7;Thymocytes: 49.1" "Cell type enriched" "Detected in single" 251 "leukocyte: 186.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 8 "gdT-cell: 1379.5;MAIT T-cell: 871.1;memory CD8 T-cell: 892.9;naive CD8 T-cell: 638.1;NK-cell: 2280.8" "Group enriched" "Detected in all" 39 "NK-cells: 2280.8;T-cells: 1379.5" "Cancer enriched" "Detected in some" 16 "Leukemia: 40.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Thyroid gland - T-cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB016345, HPA066903" Enhanced "Intracellular and membrane" Enzyme NA NA 300000 "Cluster 15: NK-cells - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 25: Non-specific - Transcription" "Cluster 59: Leukemia - T-cell receptor" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" "CAB016345: , HPA066903: " "unprognostic (3.30e-2)" "potential prognostic favorable (8.49e-5)" "unprognostic (5.52e-3)" "unprognostic (9.11e-2)" "unprognostic (1.92e-1)" "unprognostic (4.09e-2)" "unprognostic (1.83e-2)" "unprognostic (3.67e-1)" "unprognostic (2.50e-3)" "unprognostic (1.10e-1)" "unprognostic (3.05e-1)" "unprognostic (1.67e-1)" "unprognostic (1.52e-3)" "unprognostic (3.20e-2)" "potential prognostic favorable (7.93e-4)" "unprognostic (3.66e-3)" "unprognostic (9.53e-2)" "unprognostic (2.11e-1)" "unprognostic (2.43e-1)" "unprognostic (1.69e-1)" "unprognostic (6.33e-3)" "unprognostic (1.21e-2)" "unprognostic (3.82e-3)" "unprognostic (2.61e-1)" "unprognostic (2.56e-2)" "unprognostic (1.58e-1)" "unprognostic (3.38e-2)" "unprognostic (4.98e-2)" "unprognostic (1.54e-1)" "unprognostic (2.15e-1)" "unprognostic (1.09e-1)" CTSZ CTSX ENSG00000101160 "Cathepsin Z" Q9UBR2 20 58985686-59008238 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "cDC: 681.9;Hepatocytes: 431.0;Hofbauer cells: 1473.3;Kupffer cells: 483.8;Macrophages: 639.8;monocytes: 531.2;pDCs: 460.9" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 143.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025114, HPA049876, HPA053504" Supported Supported Vesicles "Intracellular and membrane" Enzyme NA NA 22000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 28: Liver & Adrenal gland - Secretion" "Cluster 21: Non-specific - Metabolism" "Cluster 15: Kidney cancer - Membrane components" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 17 Vesicles "CAB025114: , HPA049876: , HPA053504: " "unprognostic (3.42e-1)" "unprognostic (3.54e-1)" "unprognostic (1.43e-1)" "unprognostic (2.25e-3)" "unprognostic (2.10e-1)" "unprognostic (8.04e-2)" "unprognostic (3.21e-2)" "unprognostic (1.32e-1)" "unprognostic (8.36e-2)" "unprognostic (1.11e-1)" "unprognostic (1.61e-3)" "unprognostic (7.50e-2)" "unprognostic (4.01e-1)" "unprognostic (2.40e-2)" "unprognostic (7.29e-2)" "unprognostic (6.38e-3)" "unprognostic (2.63e-2)" "unprognostic (5.37e-2)" "unprognostic (2.68e-1)" "unprognostic (8.39e-2)" "unprognostic (5.27e-2)" "unprognostic (5.58e-2)" "unprognostic (3.44e-2)" "unprognostic (3.45e-1)" "unprognostic (7.27e-2)" "unprognostic (2.11e-2)" "unprognostic (3.69e-2)" "unprognostic (1.48e-1)" "unprognostic (4.76e-2)" "unprognostic (7.47e-3)" "unprognostic (2.37e-1)" CTTN EMS1 ENSG00000085733 Cortactin Q14247 11 70398404-70436584 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Endocytosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 99.9;Bergmann glia: 85.5;Brain excitatory neurons: 96.3;Oligodendrocytes: 157.7;Papillary tip epithelial cells: 126.6;Platelets: 345.7;Proximal tubule cells: 100.3;Renal collecting duct intercalated cells: 115.3;Renal collecting duct principal cells: 134.9;Renal connecting tubule cells: 85.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 1.2;neutrophil: 2.1" "Lineage enriched" "Detected in single" 5 "granulocytes: 2.1" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011235, HPA057242" Supported Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA 19000000 "Cluster 35: Neutrophils - Protein binding" "Cluster 74: Non-specific - Signal transduction" "Cluster 27: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 47: Platelets - Hemostasis" 154 "Vesicles, Plasma membrane" "Golgi apparatus" "CAB011235: , HPA057242: " "unprognostic (3.50e-1)" "unprognostic (6.86e-2)" "unprognostic (1.76e-2)" "unprognostic (5.63e-3)" "unprognostic (2.15e-1)" "unprognostic (1.41e-1)" "unprognostic (1.71e-1)" "unprognostic (9.11e-3)" "potential prognostic unfavorable (9.69e-5)" "potential prognostic unfavorable (4.20e-4)" "unprognostic (1.43e-3)" "unprognostic (1.86e-1)" "unprognostic (1.60e-3)" "potential prognostic unfavorable (8.33e-4)" "unprognostic (8.81e-3)" "unprognostic (4.40e-2)" "potential prognostic unfavorable (7.98e-5)" "unprognostic (3.77e-2)" "unprognostic (2.55e-1)" "unprognostic (4.82e-2)" "unprognostic (1.81e-1)" "potential prognostic unfavorable (4.54e-4)" "unprognostic (6.55e-3)" "unprognostic (1.32e-1)" "unprognostic (1.15e-1)" "unprognostic (1.14e-1)" "unprognostic (3.01e-1)" "unprognostic (6.59e-2)" "unprognostic (3.54e-1)" "unprognostic (1.59e-1)" "unprognostic (3.18e-1)" CTTNBP2 "C7orf8, CORTBP2, KIAA1758, Orf4" ENSG00000077063 "Cortactin binding protein 2" Q8WZ74 7 117710651-117874139 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 277.2;Choroid plexus epithelial cells: 265.4;Epididymal clear cells: 265.4;Mast cells: 355.4;Microglia: 299.7;Müller glia: 242.8;Oligodendrocyte progenitor cells: 601.7;Oligodendrocytes: 459.3;Podocytes: 315.9;Proximal tubule cells: 290.3;Retinal amacrine cells: 307.1;Retinal horizontal cells: 230.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 18.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "non-classical monocyte: 7.9" "Lineage enriched" "Detected in single" 26 "monocytes: 7.9" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Minor salivary gland basal cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009151, HPA044654" Enhanced Approved "Midbody ring,Cytosol" Yes No "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 49: HMC-1 - Innate immune response" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 32 "Midbody ring" Cytosol "CAB009151: , HPA044654: " "unprognostic (1.55e-2)" "unprognostic (1.12e-1)" "unprognostic (2.02e-1)" "unprognostic (1.07e-2)" "unprognostic (1.88e-1)" "unprognostic (1.44e-2)" "unprognostic (5.92e-2)" "unprognostic (6.18e-3)" "unprognostic (2.60e-2)" "potential prognostic favorable (9.94e-4)" "unprognostic (6.39e-2)" "unprognostic (4.41e-2)" "unprognostic (9.11e-2)" "unprognostic (7.45e-2)" "unprognostic (1.62e-1)" "unprognostic (2.14e-3)" "unprognostic (1.72e-1)" "unprognostic (2.17e-1)" "unprognostic (1.40e-1)" "unprognostic (6.08e-3)" "unprognostic (9.73e-2)" "unprognostic (3.53e-1)" "unprognostic (2.86e-2)" "unprognostic (1.05e-1)" "unprognostic (1.23e-1)" "unprognostic (6.39e-2)" "unprognostic (7.64e-2)" "unprognostic (3.50e-2)" CTTNBP2NL DKFZp547A023 ENSG00000143079 "CTTNBP2 N-terminal like" Q9P2B4 1 112396214-112463456 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "cDC: 243.2;Esophageal apical cells: 376.9;Microglia: 346.1" "Group enriched" "Detected in all" 5 "central nervous system macrophage: 428.6;endothelial cell: 294.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 8.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Liver - Vascular endothelial cells, Lung - Endothelial cells, Skeletal muscle - Endothelial cells, Spleen - Endothelial cells, Thyroid gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007301 Approved Approved "Nucleoli fibrillar center,Cytosol" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 58 "Nucleoli fibrillar center, Cytosol" "HPA007301: " "unprognostic (2.73e-2)" "unprognostic (1.29e-1)" "unprognostic (1.67e-1)" "unprognostic (2.88e-2)" "potential prognostic favorable (2.46e-4)" "unprognostic (1.60e-2)" "unprognostic (2.08e-2)" "unprognostic (2.55e-1)" "unprognostic (1.15e-1)" "unprognostic (3.01e-2)" "validated prognostic favorable (2.47e-8)" "validated prognostic favorable (2.93e-6)" "unprognostic (1.91e-1)" "unprognostic (1.91e-2)" "unprognostic (2.63e-1)" "unprognostic (2.01e-1)" "unprognostic (4.30e-3)" "unprognostic (1.03e-1)" "unprognostic (2.77e-1)" "unprognostic (3.42e-2)" "unprognostic (2.92e-3)" "unprognostic (2.11e-3)" "unprognostic (4.06e-2)" "unprognostic (2.47e-2)" "potential prognostic favorable (7.68e-5)" "unprognostic (1.65e-1)" "unprognostic (4.67e-2)" "unprognostic (3.10e-1)" "unprognostic (3.87e-1)" "unprognostic (2.15e-2)" "unprognostic (5.44e-2)" CTU1 "ATPBD3, MGC17332, NCS6" ENSG00000142544 "Cytosolic thiouridylase subunit 1" Q7Z7A3 19 51097606-51108409 "Predicted intracellular proteins" "tRNA processing" "RNA-binding, Transferase, tRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 35.4;Suprabasal keratinocytes: 34.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052664, HPA053797" Uncertain Supported Cytosol NA NA "Cluster 64: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 4: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 18 Cytosol "HPA052664: , HPA053797: " "unprognostic (2.47e-3)" "unprognostic (1.44e-1)" "unprognostic (6.48e-2)" "potential prognostic unfavorable (7.91e-4)" "unprognostic (1.86e-2)" "unprognostic (1.22e-3)" "unprognostic (2.04e-1)" "unprognostic (5.29e-2)" "unprognostic (5.16e-2)" "unprognostic (2.25e-1)" "potential prognostic unfavorable (3.22e-5)" "unprognostic (1.71e-1)" "unprognostic (4.16e-2)" "unprognostic (5.72e-3)" "unprognostic (4.22e-2)" "unprognostic (2.84e-3)" "unprognostic (4.50e-3)" "unprognostic (1.37e-2)" "unprognostic (2.42e-1)" "unprognostic (2.12e-1)" "unprognostic (1.57e-2)" "unprognostic (7.28e-2)" "unprognostic (7.96e-3)" "unprognostic (2.51e-1)" "unprognostic (2.33e-1)" "unprognostic (1.86e-1)" "unprognostic (1.74e-1)" "unprognostic (6.53e-2)" "unprognostic (6.79e-2)" "unprognostic (1.23e-1)" CTU2 "C16orf84, NCS2" ENSG00000174177 "Cytosolic thiouridylase subunit 2" Q2VPK5 16 88706483-88715396 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "tRNA processing" "Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 29.2;Early primary spermatocytes: 30.0;Oocytes: 64.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041135 Uncertain Approved Mitochondria,Cytosol NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 24: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 17: Non-specific - RNA processing" "Mitochondria, Cytosol" "HPA041135: " "unprognostic (5.95e-3)" "unprognostic (1.35e-1)" "unprognostic (2.21e-2)" "unprognostic (8.36e-3)" "unprognostic (8.43e-3)" "unprognostic (5.84e-2)" "unprognostic (2.97e-2)" "unprognostic (1.97e-3)" "unprognostic (2.08e-2)" "unprognostic (6.23e-2)" "potential prognostic unfavorable (5.72e-7)" "unprognostic (1.53e-2)" "unprognostic (3.72e-2)" "validated prognostic unfavorable (2.65e-5)" "validated prognostic unfavorable (8.12e-4)" "unprognostic (1.25e-1)" "unprognostic (1.40e-2)" "unprognostic (6.30e-2)" "unprognostic (2.62e-1)" "unprognostic (1.42e-1)" "unprognostic (1.01e-1)" "unprognostic (2.40e-3)" "unprognostic (1.38e-1)" "unprognostic (3.16e-2)" "unprognostic (4.63e-2)" "unprognostic (5.76e-2)" "unprognostic (4.77e-2)" "unprognostic (5.00e-2)" "unprognostic (1.87e-1)" "unprognostic (7.24e-2)" "unprognostic (5.72e-2)" CTXN1 FLJ25968 ENSG00000178531 "Cortexin 1" P60606 19 7924491-7926135 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in many" 9 "brain: 691.5" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 47.7;Endometrial ciliated cells: 129.6;Ependymal cells: 123.5;Epididymal efferent duct ciliated cells: 115.0;Epididymal principal cells: 130.5;Fallopian tube ciliated cells: 311.6;Other brain neurons: 59.8;Respiratory ciliated cells: 230.4;Respiratory deuterosomal cells: 48.7" "Cell type enhanced" "Detected in all" "ependymal cell: 192.1" "Cancer enhanced" "Detected in all" "Ovary Serous Cystadenocarcinoma (TCGA): 195.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Smooth muscle cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016669 Uncertain Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 98: Neurons - Neurotransmission & signaling" 1 Nucleoplasm "Plasma membrane, Cell Junctions" "HPA016669: " "unprognostic (7.84e-2)" "unprognostic (2.38e-2)" "unprognostic (1.26e-1)" "unprognostic (4.20e-2)" "unprognostic (2.30e-2)" "unprognostic (9.82e-2)" "unprognostic (4.77e-2)" "unprognostic (2.10e-1)" "unprognostic (2.96e-2)" "unprognostic (3.01e-2)" "potential prognostic unfavorable (9.71e-6)" "unprognostic (1.59e-3)" "unprognostic (2.51e-1)" "unprognostic (6.43e-2)" "unprognostic (3.43e-1)" "unprognostic (9.29e-2)" "unprognostic (4.10e-2)" "unprognostic (2.29e-2)" "unprognostic (1.22e-1)" "unprognostic (1.44e-3)" "unprognostic (7.26e-2)" "unprognostic (7.96e-2)" "unprognostic (3.92e-3)" "unprognostic (1.86e-1)" "unprognostic (1.87e-1)" "unprognostic (1.05e-1)" "unprognostic (1.09e-2)" "unprognostic (7.95e-2)" "unprognostic (4.35e-2)" CTXN2 ENSG00000233932 "Cortexin 2" P0C2S0 15 48178122-48203758 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 2.2;pituitary gland: 1.2;retina: 1.1" "Cell type enriched" "Detected in some" 4 "Cardiomyocytes: 37.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enteroendocrine cells, Pituitary gland - Lactotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA053168 Uncertain NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" "HPA053168: " "unprognostic (1.27e-1)" CTXN3 ENSG00000205279 "Cortexin 3" Q4LDR2 5 127649082-127658630 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 19.8;kidney: 74.4;skeletal muscle: 12.4" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 5.0;Brain inhibitory neurons: 9.3;Corticotrophs: 13.6;Lactotrophs: 7.3;Other brain neurons: 7.2;Proximal tubule cells: 2.8;Thymic myoid cells: 5.4" "Group enriched" "Detected in many" 7 "lower rhombic lip: 53.8;midbrain-derived inhibitory: 70.4;thalamic excitatory: 19.2" "Group enriched" "Detected in some" 8 "Kidney Renal Clear Cell Carcinoma (TCGA): 3.0;Kidney Renal Papillary Cell Carcinoma (TCGA): 1.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "olfactory bulb: 32.6" HPA063194 Approved "Principal piece,End piece" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 13: Non-specific - Mixed function" "Cluster 109: Neurons - Neuronal signaling" 51 "Principal piece, End piece" "HPA063194: " "unprognostic (1.85e-1)" "potential prognostic favorable (9.25e-6)" "unprognostic (1.30e-2)" "unprognostic (9.28e-2)" CTXND1 LINC01314 ENSG00000259417 "Cortexin domain containing 1" A0A1B0GTU2 15 80195481-80252213 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 25.1;liver: 8.7" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 75.8;Astrocytes: 128.9;Bergmann glia: 195.2;Brain excitatory neurons: 64.2;Cholangiocytes: 48.6;Ependymal cells: 72.1;Epididymal efferent duct absorptive cells: 62.1;Hepatocytes: 43.5;Melanocytes: 78.5;Oligodendrocyte progenitor cells: 105.6;Pituicytes/FSCs: 63.7;Schwann cells: 62.4" "Cell type enhanced" "Detected in many" "Bergmann glia: 209.9;hippocampal CA1-3: 295.0;hippocampal CA4: 199.8" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 14.9;Thyroid Carcinoma (TCGA): 7.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "Rhabdoid: 6.1;skin cancer: 3.1" "Adrenal gland - Adrenal cortex cells, Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Lung - Alveolar cells type 2, Spleen - Fibroblasts_2" "Region enriched" "Detected in all" 4 "hippocampal formation: 35.1" "Region enriched" "Detected in all" 10 "hippocampal formation: 1361.3" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 29: Forebrain - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 28: Astrocytes - Homeostasis & neuron support" "unprognostic (3.16e-1)" "unprognostic (2.52e-1)" "unprognostic (2.28e-1)" "unprognostic (5.10e-2)" "unprognostic (2.20e-2)" "unprognostic (4.96e-1)" "unprognostic (1.84e-3)" "unprognostic (1.52e-1)" CTXND2 ENSG00000283324 "Cortexin domain containing 2" A0A1B0GV90 1 150887136-150913292 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Early primary spermatocytes: 2.6;Extravillous trophoblasts: 9.7;Fallopian tube ciliated cells: 4.6;Granulosa cells: 4.1;Oocytes: 13.8;Undifferentiated spermatogonia: 11.8" "Low cell type specificity" "Detected in some" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pituitary gland - Gonadotropes" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA "Cluster 9: Non-specific - Receptor signaling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" CUBN "gp280, IFCR, MGA1" ENSG00000107611 Cubilin O60494 10 16823966-17129811 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Cholesterol metabolism, Endocytosis, Lipid metabolism, Protein transport, Steroid metabolism, Sterol metabolism, Transport" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "kidney: 131.1" "Group enriched" "Detected in many" 8 "Enterocytes: 928.6;Proximal tubule cells: 2874.4" "Cell type enhanced" "Detected in all" "ependymal cell: 198.9" "Group enriched" "Detected in some" 14 "Kidney Renal Clear Cell Carcinoma (TCGA): 56.3;Kidney Renal Papillary Cell Carcinoma (TCGA): 17.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Rhabdoid: 17.7" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Skeletal muscle - Fibroblasts, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA004133, HPA043854" Enhanced "Intracellular and membrane" Receptor NA NA 260000 "Cluster 72: Kidney - Transmembrane transport" "Cluster 49: Hindbrain - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 88: Proximal tubular cells - Transmembrane transport" 2 "HPA004133: , HPA043854: " "unprognostic (2.01e-2)" "unprognostic (7.24e-2)" "unprognostic (9.68e-2)" "validated prognostic favorable (3.05e-12)" "validated prognostic favorable (6.75e-4)" "unprognostic (1.49e-3)" "unprognostic (1.67e-1)" "unprognostic (1.02e-1)" "unprognostic (7.07e-2)" CUEDC1 ENSG00000180891 "CUE domain containing 1" Q9NWM3 17 57861243-57955412 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 205.4;Cone photoreceptor cells: 223.6;Rod photoreceptor cells: 263.0" "Cell type enhanced" "Detected in all" "oligodendrocyte: 222.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "plasmacytoid DC: 21.8" "Lineage enriched" "Detected in many" 9 "dendritic cells: 21.8" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023050, HPA024836" Approved Approved "Plasma membrane,Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Primary cilium tip,Centrosome,Basal body,Cytosol" Yes NA "Cluster 29: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 27: Breast cancer - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" 35 "Plasma membrane, Primary cilium, Centrosome, Basal body" "Microtubules, Cytokinetic bridge, Mitotic spindle, Primary cilium tip, Cytosol" "HPA023050: , HPA024836: " "unprognostic (4.30e-2)" "unprognostic (5.41e-2)" "unprognostic (2.90e-1)" "unprognostic (2.92e-2)" "unprognostic (7.39e-2)" "unprognostic (1.45e-1)" "unprognostic (1.90e-1)" "potential prognostic favorable (5.67e-4)" "unprognostic (1.24e-1)" "unprognostic (1.08e-3)" "potential prognostic favorable (2.17e-5)" "unprognostic (1.62e-1)" "unprognostic (1.88e-1)" "validated prognostic unfavorable (4.65e-4)" "validated prognostic unfavorable (5.25e-4)" "unprognostic (1.73e-1)" "unprognostic (4.39e-3)" "unprognostic (2.13e-1)" "unprognostic (2.72e-2)" "unprognostic (3.69e-2)" "unprognostic (8.11e-2)" "unprognostic (6.48e-2)" "unprognostic (3.50e-2)" "unprognostic (3.37e-1)" "unprognostic (2.84e-1)" "unprognostic (8.06e-3)" "unprognostic (3.50e-2)" "unprognostic (2.26e-1)" "unprognostic (3.19e-2)" "unprognostic (3.75e-3)" "unprognostic (1.21e-2)" CUEDC2 "C10orf66, MGC2491" ENSG00000107874 "CUE domain containing 2" Q9H467 10 102423245-102432584 "Disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036544, HPA041829" Uncertain Supported "Nucleoplasm,Nuclear membrane,Plasma membrane,Primary cilium tip,Cytosol" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 97: Non-specific - Cellular respiration" 14 "Nucleoplasm, Cytosol" "Nuclear membrane, Plasma membrane, Primary cilium tip" "HPA036544: , HPA041829: " "unprognostic (1.15e-1)" "unprognostic (9.42e-2)" "unprognostic (2.42e-1)" "unprognostic (1.25e-1)" "unprognostic (5.58e-2)" "unprognostic (1.97e-1)" "unprognostic (1.71e-1)" "potential prognostic favorable (3.76e-4)" "unprognostic (1.06e-1)" "unprognostic (1.99e-2)" "potential prognostic favorable (3.53e-4)" "unprognostic (2.25e-1)" "unprognostic (1.21e-3)" "potential prognostic unfavorable (5.31e-5)" "unprognostic (3.23e-1)" "unprognostic (2.83e-1)" "unprognostic (4.30e-2)" "unprognostic (7.71e-2)" "unprognostic (1.47e-1)" "unprognostic (1.98e-1)" "unprognostic (1.57e-1)" "unprognostic (9.01e-2)" "unprognostic (1.19e-1)" "unprognostic (7.36e-2)" "unprognostic (2.24e-1)" "potential prognostic favorable (5.60e-4)" "unprognostic (6.51e-2)" "unprognostic (1.88e-1)" "unprognostic (3.81e-1)" "unprognostic (7.59e-2)" "unprognostic (1.40e-2)" CUL1 ENSG00000055130 "Cullin 1" Q13616 7 148697914-148801110 "Cancer-related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 579.8;Late spermatids: 949.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002676, HPA029882, HPA064584" Supported Approved Nucleoplasm,Nucleoli,Cytosol NA NA 170000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 61: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 39: Non-specific - Transcription" "Cluster 103: Non-specific - Basic cellular processes" 241 Nucleoplasm "Nucleoli, Cytosol" "CAB002676: , HPA029882: , HPA064584: " "unprognostic (3.93e-2)" "unprognostic (1.15e-1)" "unprognostic (6.93e-2)" "unprognostic (9.15e-2)" "unprognostic (6.28e-2)" "unprognostic (1.80e-3)" "unprognostic (6.57e-2)" "unprognostic (3.84e-2)" "unprognostic (2.34e-1)" "unprognostic (1.85e-2)" "potential prognostic favorable (1.25e-4)" "unprognostic (1.77e-2)" "unprognostic (6.35e-2)" "unprognostic (8.47e-3)" "unprognostic (4.11e-3)" "unprognostic (4.19e-3)" "unprognostic (5.99e-2)" "unprognostic (6.68e-2)" "unprognostic (1.26e-1)" "unprognostic (3.74e-2)" "unprognostic (1.32e-1)" "unprognostic (2.65e-1)" "unprognostic (3.18e-1)" "unprognostic (7.41e-2)" "unprognostic (2.26e-1)" "unprognostic (2.27e-1)" "unprognostic (6.23e-2)" "unprognostic (1.64e-1)" "unprognostic (1.41e-1)" "unprognostic (1.37e-1)" "unprognostic (3.02e-1)" CUL2 ENSG00000108094 "Cullin 2" Q13617 10 35008504-35127006 "Cancer-related genes, Essential proteins, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 417.8;Late primary spermatocytes: 181.5;Late spermatids: 290.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002677, HPA024578" Approved Enhanced Nucleoplasm NA NA 14000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 52: Non-specific - Mitochondria" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 136 Nucleoplasm "CAB002677: , HPA024578: " "unprognostic (1.25e-2)" "unprognostic (5.45e-3)" "unprognostic (1.19e-1)" "unprognostic (1.29e-1)" "unprognostic (3.31e-1)" "unprognostic (1.36e-1)" "unprognostic (9.43e-2)" "potential prognostic favorable (1.04e-5)" "unprognostic (2.90e-1)" "unprognostic (2.98e-3)" "potential prognostic favorable (3.30e-6)" "unprognostic (2.12e-1)" "unprognostic (5.71e-3)" "potential prognostic unfavorable (1.08e-5)" "unprognostic (6.20e-3)" "unprognostic (5.55e-2)" "unprognostic (2.34e-2)" "unprognostic (3.72e-1)" "unprognostic (1.97e-1)" "unprognostic (2.92e-2)" "unprognostic (1.55e-3)" "unprognostic (1.74e-2)" "unprognostic (1.11e-2)" "unprognostic (7.89e-2)" "unprognostic (1.29e-1)" "unprognostic (2.84e-1)" "unprognostic (2.97e-1)" "unprognostic (3.64e-1)" "unprognostic (2.67e-1)" "unprognostic (6.58e-2)" "unprognostic (1.12e-1)" CUL3 ENSG00000036257 "Cullin 3" Q13618 2 224470150-224585397 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Cilium biogenesis/degradation, ER-Golgi transport, Mitosis, Transport, Ubl conjugation pathway" "Autism spectrum disorder, Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 193.0" "Cell type enhanced" "Detected in all" "Neutrophils: 728.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002678, HPA072059" Supported Supported "Nucleoplasm,Microtubules,Cytokinetic bridge" Yes NA 69000 "Cluster 21: Neutrophils - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 858 Nucleoplasm "Microtubules, Cytokinetic bridge" "CAB002678: , HPA072059: " "unprognostic (1.54e-2)" "unprognostic (1.24e-3)" "unprognostic (1.50e-1)" "unprognostic (1.01e-1)" "unprognostic (2.04e-1)" "unprognostic (1.06e-1)" "unprognostic (1.53e-1)" "unprognostic (4.41e-1)" "unprognostic (2.77e-1)" "unprognostic (4.77e-3)" "validated prognostic favorable (8.06e-6)" "validated prognostic favorable (8.36e-4)" "unprognostic (1.77e-1)" "unprognostic (5.77e-3)" "unprognostic (1.23e-2)" "unprognostic (2.69e-2)" "unprognostic (1.84e-1)" "unprognostic (2.14e-1)" "unprognostic (1.11e-1)" "unprognostic (6.65e-2)" "unprognostic (1.21e-1)" "unprognostic (1.65e-2)" "unprognostic (8.12e-2)" "unprognostic (1.20e-1)" "unprognostic (7.76e-2)" "unprognostic (9.87e-2)" "unprognostic (2.72e-3)" "unprognostic (1.14e-1)" "unprognostic (4.49e-2)" "unprognostic (1.38e-1)" "unprognostic (3.16e-1)" CUL4A ENSG00000139842 "Cullin 4A" Q13619 13 113208193-113267108 "Predicted intracellular proteins" "Biological rhythms, DNA damage, DNA repair, Host-virus interaction, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 160.8" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058979 Approved Nucleoplasm NA NA 18000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 12: Non-specific - Vasculature" "Cluster 19: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 155 Nucleoplasm "HPA058979: " "unprognostic (4.90e-2)" "unprognostic (2.62e-1)" "unprognostic (1.96e-1)" "unprognostic (1.99e-2)" "unprognostic (8.17e-2)" "unprognostic (1.24e-1)" "unprognostic (8.47e-2)" "unprognostic (2.71e-2)" "unprognostic (3.21e-2)" "unprognostic (2.94e-1)" "potential prognostic favorable (4.58e-4)" "unprognostic (5.18e-3)" "unprognostic (9.02e-3)" "unprognostic (3.79e-3)" "unprognostic (8.67e-3)" "unprognostic (3.88e-3)" "unprognostic (9.31e-3)" "unprognostic (3.63e-2)" "unprognostic (1.49e-1)" "unprognostic (1.17e-1)" "unprognostic (1.63e-1)" "unprognostic (3.98e-2)" "unprognostic (1.02e-1)" "unprognostic (6.12e-2)" "unprognostic (1.88e-1)" "unprognostic (2.10e-1)" "unprognostic (1.43e-1)" "unprognostic (3.37e-2)" "unprognostic (1.36e-1)" "unprognostic (3.53e-2)" "unprognostic (1.52e-1)" CUL4B ENSG00000158290 "Cullin 4B" Q13620 X 120505920-120604074 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair, Ubl conjugation pathway" "Cancer-related genes, Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 144.1;Epicardial cells: 166.0;Late spermatids: 307.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003046, HPA011880, CAB017786, HPA058979" Enhanced Enhanced Nucleoplasm NA NA 5900 "Cluster 30: Non-specific - DNA binding" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 36: Non-specific - mRNA processing" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 190 Nucleoplasm "CAB017786: , HPA003046: , HPA011880: , HPA058979: " "unprognostic (2.73e-1)" "unprognostic (2.25e-2)" "unprognostic (1.14e-1)" "unprognostic (8.46e-2)" "unprognostic (4.12e-2)" "unprognostic (1.69e-2)" "unprognostic (7.48e-2)" "unprognostic (3.19e-1)" "unprognostic (2.61e-1)" "potential prognostic unfavorable (7.32e-4)" "potential prognostic favorable (1.11e-4)" "unprognostic (8.17e-2)" "unprognostic (5.14e-3)" "unprognostic (3.05e-3)" "unprognostic (2.57e-3)" "unprognostic (5.08e-3)" "unprognostic (7.57e-3)" "unprognostic (1.55e-1)" "unprognostic (3.96e-2)" "unprognostic (2.24e-1)" "unprognostic (3.18e-2)" "unprognostic (8.81e-2)" "unprognostic (8.22e-3)" "unprognostic (6.19e-2)" "unprognostic (5.49e-2)" "unprognostic (3.38e-1)" "unprognostic (1.21e-1)" "unprognostic (5.99e-2)" "unprognostic (1.63e-1)" "unprognostic (1.04e-2)" "unprognostic (2.37e-2)" CUL5 VACM-1 ENSG00000166266 "Cullin 5" Q93034 11 108008898-108107761 "Cancer-related genes, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002185, CAB017787" Approved Approved "Golgi apparatus,Cytosol" NA NA 6800 "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 150 "Golgi apparatus, Cytosol" "CAB017787: , HPA002185: " "unprognostic (1.12e-2)" "unprognostic (1.31e-2)" "unprognostic (9.13e-2)" "unprognostic (6.37e-2)" "unprognostic (3.78e-1)" "unprognostic (2.41e-1)" "unprognostic (1.51e-1)" "unprognostic (1.94e-2)" "unprognostic (1.42e-1)" "unprognostic (9.33e-3)" "potential prognostic favorable (2.07e-6)" "unprognostic (1.04e-2)" "unprognostic (5.54e-3)" "unprognostic (1.45e-2)" "unprognostic (2.02e-1)" "unprognostic (3.74e-1)" "unprognostic (6.10e-2)" "unprognostic (5.80e-2)" "unprognostic (3.63e-2)" "unprognostic (1.37e-1)" "unprognostic (5.77e-3)" "unprognostic (2.44e-2)" "unprognostic (5.35e-2)" "unprognostic (2.83e-2)" "potential prognostic favorable (8.14e-4)" "unprognostic (7.37e-2)" "unprognostic (1.01e-2)" "unprognostic (6.58e-2)" "unprognostic (1.68e-1)" "unprognostic (6.36e-2)" "unprognostic (2.26e-1)" CUL7 "dJ20C7.5, KIAA0076" ENSG00000044090 "Cullin 7" Q14999 6 43037617-43053943 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Pituitary gland - Somatotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015449, HPA030095, HPA030096" Approved NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 28: Non-specific - Nuclear processes" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 77 "CAB015449: , HPA030095: , HPA030096: " "unprognostic (3.64e-1)" "unprognostic (9.06e-2)" "unprognostic (1.42e-1)" "unprognostic (1.04e-2)" "unprognostic (4.95e-2)" "unprognostic (1.00e-1)" "unprognostic (1.97e-2)" "potential prognostic unfavorable (1.97e-5)" "unprognostic (1.56e-2)" "unprognostic (1.97e-3)" "potential prognostic favorable (5.88e-5)" "unprognostic (5.55e-1)" "unprognostic (3.61e-1)" "unprognostic (2.24e-2)" "unprognostic (4.43e-2)" "unprognostic (1.60e-1)" "potential prognostic unfavorable (5.63e-4)" "unprognostic (5.53e-2)" "unprognostic (1.27e-1)" "unprognostic (6.25e-2)" "unprognostic (1.84e-1)" "unprognostic (1.31e-1)" "unprognostic (1.77e-1)" "unprognostic (1.60e-1)" "unprognostic (2.67e-2)" "unprognostic (2.67e-1)" "unprognostic (9.35e-3)" "unprognostic (3.12e-1)" "unprognostic (1.95e-1)" "unprognostic (3.42e-2)" "unprognostic (1.82e-1)" CUL9 "H7AP1, KIAA0708, PARC" ENSG00000112659 "Cullin 9" Q8IWT3 6 43182184-43224587 "Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 19 "Early spermatids: 684.4;Late spermatids: 2360.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016434, HPA052004" Approved Approved Cytosol No No "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 11 Cytosol "HPA016434: , HPA052004: " "unprognostic (1.44e-1)" "unprognostic (5.05e-2)" "unprognostic (1.04e-1)" "unprognostic (3.42e-2)" "unprognostic (7.17e-2)" "unprognostic (1.35e-1)" "unprognostic (1.17e-1)" "unprognostic (7.67e-3)" "potential prognostic favorable (1.85e-4)" "unprognostic (3.51e-2)" "potential prognostic favorable (7.82e-7)" "unprognostic (6.11e-3)" "unprognostic (2.92e-2)" "unprognostic (4.13e-2)" "unprognostic (4.22e-1)" "unprognostic (3.58e-2)" "unprognostic (1.27e-1)" "unprognostic (1.01e-1)" "unprognostic (4.55e-2)" "unprognostic (7.70e-2)" "potential prognostic favorable (9.25e-4)" "unprognostic (2.48e-1)" "unprognostic (2.83e-2)" "unprognostic (3.51e-1)" "unprognostic (1.04e-2)" "unprognostic (1.10e-1)" "unprognostic (1.37e-1)" "unprognostic (1.76e-1)" "unprognostic (2.28e-1)" "unprognostic (2.07e-2)" "unprognostic (1.41e-1)" CUTA "ACHAP, C6orf82" ENSG00000112514 "CutA divalent cation tolerance homolog" O60888 6 33416442-33418317 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 474.0;Late spermatids: 484.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Kidney - Fibroblasts, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016787, HPA064369, HPA070199" Approved Approved "Plasma membrane,Focal adhesion sites" "Secreted to blood" "No annotated function" NA NA 6700000 "Cluster 39: T-cells - T-cell receptor" "Cluster 70: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 28: Non-specific - Nuclear processes" "Cluster 67: Plasma cells - Plasma cell differentiation" 4 "Plasma membrane, Focal adhesion sites" "CAB016787: , HPA064369: , HPA070199: " "unprognostic (3.57e-2)" "unprognostic (1.51e-1)" "unprognostic (1.08e-1)" "unprognostic (3.50e-3)" "unprognostic (1.58e-1)" "unprognostic (2.65e-2)" "unprognostic (9.56e-2)" "unprognostic (1.08e-1)" "unprognostic (1.11e-2)" "unprognostic (3.25e-1)" "potential prognostic favorable (1.46e-4)" "unprognostic (6.74e-3)" "unprognostic (2.15e-1)" "unprognostic (7.73e-3)" "potential prognostic unfavorable (2.68e-4)" "unprognostic (3.95e-3)" "unprognostic (4.38e-1)" "unprognostic (1.38e-2)" "unprognostic (1.40e-1)" "unprognostic (1.96e-2)" "unprognostic (1.46e-1)" "unprognostic (3.51e-3)" "unprognostic (3.01e-3)" "unprognostic (1.91e-1)" "unprognostic (2.76e-3)" "unprognostic (2.58e-3)" "unprognostic (1.70e-1)" "unprognostic (1.24e-1)" "unprognostic (2.28e-1)" "unprognostic (8.16e-2)" "unprognostic (1.94e-1)" CUTC CGI-32 ENSG00000119929 "CutC copper transporter" Q9NTM9 10 99702558-99756134 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "skeletal muscle: 361.4;tongue: 190.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 191.1;Late primary spermatocytes: 185.8;Myonuclei: 339.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Skeletal myocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038619, HPA058231" Enhanced Enhanced Nucleoplasm,Nucleoli,Cytosol No No "Cluster 22: Eosinophils - Transcription" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 15 "Nucleoplasm, Cytosol" Nucleoli "HPA038619: , HPA058231: " "unprognostic (1.64e-1)" "unprognostic (1.50e-2)" "unprognostic (4.27e-1)" "unprognostic (3.08e-2)" "unprognostic (1.86e-2)" "unprognostic (2.09e-1)" "unprognostic (8.25e-2)" "potential prognostic favorable (1.22e-4)" "unprognostic (3.03e-2)" "unprognostic (1.95e-1)" "unprognostic (8.72e-2)" "unprognostic (1.77e-1)" "unprognostic (2.14e-2)" "unprognostic (2.53e-3)" "unprognostic (5.98e-2)" "unprognostic (7.90e-3)" "unprognostic (1.39e-1)" "unprognostic (1.43e-1)" "unprognostic (9.18e-2)" "unprognostic (8.46e-2)" "unprognostic (8.48e-3)" "unprognostic (2.78e-1)" "unprognostic (8.30e-2)" "unprognostic (1.41e-1)" "unprognostic (3.27e-1)" "unprognostic (1.75e-2)" "unprognostic (2.70e-2)" "unprognostic (1.00e-1)" "unprognostic (3.99e-1)" "unprognostic (3.07e-1)" "unprognostic (5.69e-3)" CUX1 "CASP, CDP, CDP/Cut, CDP/Cux, CDP1, Clox, CUT, CUTL1, CUX, Cux/CDP, GOLIM6" ENSG00000257923 "Cut like homeobox 1" "P39880, Q13948" 7 101815904-102283958 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation, Transport" "Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 2269.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 35.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003277, HPA003317" Approved Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 2: Neurons - Nucleosome" "Cluster 39: Non-specific - Transcription" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 22 "Nucleoplasm, Golgi apparatus" "HPA003277: , HPA003317: " "unprognostic (3.37e-1)" "unprognostic (1.67e-2)" "unprognostic (3.29e-1)" "unprognostic (4.11e-3)" "unprognostic (1.10e-2)" "unprognostic (1.31e-1)" "unprognostic (1.64e-2)" "unprognostic (2.55e-1)" "unprognostic (5.17e-2)" "unprognostic (1.40e-2)" "potential prognostic favorable (4.91e-5)" "unprognostic (2.35e-1)" "unprognostic (1.71e-2)" "unprognostic (4.67e-1)" "unprognostic (4.14e-1)" "unprognostic (5.54e-2)" "unprognostic (5.71e-2)" "unprognostic (4.48e-2)" "unprognostic (2.38e-2)" "unprognostic (1.30e-3)" "unprognostic (5.74e-2)" "unprognostic (1.55e-1)" "unprognostic (1.22e-2)" "unprognostic (3.52e-1)" "unprognostic (5.12e-2)" "unprognostic (3.38e-1)" "unprognostic (3.02e-1)" "unprognostic (5.47e-2)" "unprognostic (2.75e-1)" "unprognostic (9.33e-3)" "unprognostic (9.37e-2)" CUX2 "CDP2, CUTL2, KIAA0293" ENSG00000111249 "Cut like homeobox 2" O14529 12 111034165-111350554 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 13.7;choroid plexus: 10.3;liver: 19.7;prostate: 10.7" "Group enriched" "Detected in many" 4 "Choroid plexus epithelial cells: 1328.7;Hepatocytes: 629.0;pDCs: 576.9;Prostatic glandular cells: 760.8;Retinal amacrine cells: 615.7;Retinal horizontal cells: 571.0;Thymic myoid cells: 720.6" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 984.0;mammillary body: 524.1;upper-layer intratelencephalic: 516.3" "Cancer enhanced" "Detected in some" "Liver Hepatocellular Carcinoma (TCGA): 7.1;Prostate Adenocarcinoma (TCGA): 17.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 70 "plasmacytoid DC: 7.0" "Lineage enriched" "Detected in single" 70 "dendritic cells: 7.0" "Cancer enhanced" "Detected in some" "Bone cancer: 8.6;lymphoma: 7.0;Neuroblastoma: 13.8" "Pituitary gland - Corticotropes, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 36: Brain & Liver - Signaling" "Cluster 53: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" "unprognostic (1.84e-2)" "potential prognostic favorable (2.58e-4)" "unprognostic (3.61e-3)" "potential prognostic favorable (2.07e-4)" "unprognostic (2.64e-1)" "unprognostic (2.98e-1)" "unprognostic (3.87e-2)" CUZD1 "ERG-1, UO-44" ENSG00000138161 "CUB and zona pellucida like domains 1" Q86UP6 10 122832158-122846175 "Predicted membrane proteins" "Cell adhesion, Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 2112 "pancreas: 2277.5" "Cell type enriched" "Detected in some" 14 "Pancreatic acinar cells: 55.1" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in single" 77 "Pancreatic Adenocarcinoma (TCGA): 59.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA068479, HPA068660, HPA074117" Enhanced NA No "Cluster 8: Pancreas - Proteolysis" "Cluster 13: Non-specific - Mixed function" "Cluster 5: Pancreatic acinar cells - Pancreatic exocrine secretion" "HPA068479: , HPA068660: , HPA074117: " "unprognostic (1.47e-2)" "unprognostic (3.61e-2)" "unprognostic (8.46e-2)" "unprognostic (3.21e-3)" CWC15 "AD002, C11orf5, Cwf15, HSPC148" ENSG00000150316 "CWC15 spliceosome associated protein homolog" Q9P013 11 94962620-94973586 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 922.7;Late primary spermatocytes: 642.2;Oocytes: 552.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039878 Supported Supported "Nuclear speckles,Mitochondria" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 50 "Nuclear speckles" Mitochondria "HPA039878: " "unprognostic (5.66e-2)" "potential prognostic unfavorable (6.78e-4)" "unprognostic (1.85e-2)" "unprognostic (1.16e-1)" "unprognostic (5.71e-2)" "unprognostic (1.91e-2)" "unprognostic (3.15e-1)" "unprognostic (2.65e-1)" "unprognostic (2.20e-2)" "unprognostic (2.03e-1)" "unprognostic (2.52e-3)" "unprognostic (4.50e-3)" "unprognostic (3.04e-2)" "unprognostic (8.48e-3)" "unprognostic (4.13e-1)" "unprognostic (1.87e-2)" "unprognostic (7.45e-3)" "unprognostic (9.54e-2)" "unprognostic (3.09e-1)" "unprognostic (1.46e-3)" "unprognostic (3.20e-1)" "unprognostic (1.02e-3)" "potential prognostic unfavorable (4.46e-6)" "unprognostic (1.19e-1)" "unprognostic (1.41e-1)" "unprognostic (3.08e-2)" "unprognostic (1.26e-2)" "unprognostic (1.21e-1)" "unprognostic (2.43e-1)" "unprognostic (1.84e-2)" "unprognostic (1.24e-1)" CWC22 "EIF4GL, fSAPb, KIAA1604, NCM" ENSG00000163510 "CWC22 spliceosome associated protein homolog" Q9HCG8 2 179944876-180007297 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036748 Approved Supported "Nuclear speckles,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 17: Non-specific - RNA processing" 20 "Nuclear speckles" Cytosol "HPA036748: " "unprognostic (2.48e-1)" "unprognostic (1.69e-1)" "unprognostic (4.02e-1)" "unprognostic (8.18e-3)" "unprognostic (8.58e-2)" "unprognostic (1.94e-1)" "unprognostic (6.85e-2)" "unprognostic (3.09e-1)" "unprognostic (1.88e-1)" "potential prognostic unfavorable (9.80e-4)" "validated prognostic favorable (6.30e-6)" "validated prognostic favorable (3.44e-4)" "unprognostic (4.48e-3)" "unprognostic (1.39e-3)" "unprognostic (1.01e-1)" "unprognostic (7.37e-2)" "unprognostic (8.72e-2)" "unprognostic (2.87e-1)" "unprognostic (1.78e-1)" "unprognostic (1.95e-1)" "unprognostic (9.71e-2)" "unprognostic (6.14e-2)" "unprognostic (1.31e-2)" "unprognostic (5.12e-2)" "unprognostic (9.54e-2)" "unprognostic (9.12e-2)" "unprognostic (8.79e-3)" "unprognostic (5.57e-2)" "unprognostic (1.97e-1)" "unprognostic (2.79e-1)" "unprognostic (6.52e-2)" CWC25 "CCDC49, FLJ20291" ENSG00000273559 "CWC25 spliceosome associated protein homolog" Q9NXE8 17 38800441-38825355 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 58.7" "Cell type enhanced" "Detected in many" "Early spermatids: 78.3;Oocytes: 73.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 28.2" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB014874, HPA062997" Supported Enhanced "Nuclear speckles" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 15: Bone marrow - Innate immune response" "Cluster 11: White matter - Signal transduction" "Cluster 27: Breast cancer - Unknown function" "Cluster 17: Non-specific - RNA processing" 3 "Nuclear speckles" "CAB014874: , HPA062997: " "unprognostic (2.23e-1)" "unprognostic (5.22e-2)" "unprognostic (6.14e-2)" "unprognostic (8.25e-2)" "unprognostic (7.07e-2)" "unprognostic (2.13e-1)" "unprognostic (2.23e-1)" "unprognostic (1.28e-1)" "unprognostic (1.50e-1)" "unprognostic (3.04e-2)" "unprognostic (9.74e-2)" "unprognostic (1.81e-3)" "unprognostic (1.00e-2)" "unprognostic (9.48e-2)" "unprognostic (1.21e-2)" "unprognostic (2.74e-1)" "unprognostic (3.35e-1)" "unprognostic (5.83e-3)" "unprognostic (4.24e-2)" "unprognostic (5.13e-3)" "unprognostic (1.79e-1)" "unprognostic (1.48e-3)" "unprognostic (1.05e-2)" "unprognostic (4.93e-2)" "unprognostic (9.02e-2)" "unprognostic (1.88e-1)" "unprognostic (2.47e-1)" "unprognostic (1.31e-1)" CWC27 "NY-CO-10, SDCCAG-10, SDCCAG10" ENSG00000153015 "CWC27 spliceosome associated cyclophilin" Q6UX04 5 64766368-65102412 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Dwarfism, Intellectual disability, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 412.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020344, HPA024149, HPA065809" Approved Enhanced Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 9: Non-specific - Receptor signaling" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 7: Non-specific - Transcription" 1 Nucleoplasm "HPA020344: , HPA024149: , HPA065809: " "unprognostic (1.16e-1)" "unprognostic (9.99e-2)" "potential prognostic unfavorable (7.75e-4)" "unprognostic (3.71e-2)" "unprognostic (1.32e-1)" "unprognostic (5.67e-2)" "unprognostic (8.60e-2)" "unprognostic (4.14e-2)" "unprognostic (3.41e-2)" "unprognostic (9.04e-3)" "potential prognostic favorable (2.50e-6)" "unprognostic (3.04e-2)" "unprognostic (3.17e-1)" "validated prognostic unfavorable (2.60e-4)" "validated prognostic unfavorable (1.69e-4)" "potential prognostic unfavorable (9.67e-4)" "unprognostic (9.71e-2)" "unprognostic (2.10e-1)" "unprognostic (1.88e-1)" "unprognostic (2.92e-1)" "potential prognostic unfavorable (4.17e-4)" "unprognostic (8.79e-3)" "unprognostic (1.91e-3)" "unprognostic (3.75e-2)" "unprognostic (3.19e-2)" "unprognostic (1.72e-1)" "unprognostic (8.11e-2)" "unprognostic (5.00e-2)" "unprognostic (6.09e-2)" "unprognostic (1.71e-2)" "unprognostic (5.80e-2)" CWF19L1 "FLJ10998, hDrn1" ENSG00000095485 "CWF19 like cell cycle control factor 1" Q69YN2 10 100232298-100267680 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Neurodegeneration "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA036889, HPA036890" Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 39: Testis - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 11 "Nucleoplasm, Golgi apparatus" "HPA036889: , HPA036890: " "unprognostic (2.75e-2)" "unprognostic (2.85e-3)" "unprognostic (3.14e-2)" "unprognostic (3.01e-1)" "unprognostic (1.66e-1)" "unprognostic (5.39e-2)" "unprognostic (2.42e-1)" "potential prognostic favorable (1.20e-4)" "unprognostic (1.48e-1)" "unprognostic (1.79e-1)" "potential prognostic favorable (1.96e-6)" "unprognostic (2.11e-3)" "unprognostic (6.67e-2)" "unprognostic (9.79e-3)" "unprognostic (1.03e-2)" "unprognostic (1.37e-2)" "unprognostic (3.66e-1)" "unprognostic (2.43e-2)" "unprognostic (1.50e-1)" "unprognostic (5.67e-2)" "unprognostic (1.08e-3)" "unprognostic (1.07e-1)" "potential prognostic unfavorable (3.54e-5)" "unprognostic (2.18e-2)" "unprognostic (8.92e-3)" "unprognostic (2.02e-1)" "unprognostic (1.98e-1)" "unprognostic (5.06e-2)" "unprognostic (1.67e-1)" "unprognostic (7.42e-2)" "unprognostic (1.85e-1)" CWF19L2 FLJ32343 ENSG00000152404 "CWF19 like cell cycle control factor 2" Q2TBE0 11 107326360-107457825 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038166 Uncertain Approved "Nuclear speckles,Cytosol" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 25: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 105 "Nuclear speckles" Cytosol "HPA038166: " "unprognostic (8.60e-2)" "unprognostic (1.70e-1)" "unprognostic (3.29e-2)" "unprognostic (7.23e-2)" "unprognostic (2.99e-1)" "unprognostic (1.13e-1)" "unprognostic (8.34e-2)" "unprognostic (4.31e-3)" "unprognostic (4.00e-2)" "unprognostic (5.91e-3)" "validated prognostic favorable (9.33e-7)" "validated prognostic favorable (7.30e-5)" "unprognostic (2.10e-1)" "unprognostic (1.16e-2)" "unprognostic (1.92e-2)" "unprognostic (9.69e-2)" "unprognostic (1.03e-2)" "unprognostic (1.47e-1)" "unprognostic (3.06e-1)" "unprognostic (1.46e-1)" "unprognostic (1.38e-2)" "unprognostic (1.76e-2)" "potential prognostic unfavorable (1.46e-4)" "unprognostic (1.71e-1)" "unprognostic (1.02e-2)" "unprognostic (1.60e-1)" "unprognostic (1.78e-2)" "unprognostic (1.22e-1)" "unprognostic (5.61e-1)" "unprognostic (9.16e-2)" "unprognostic (1.03e-1)" CWH43 "CWH43-C, FLJ21511, PGAP2IP" ENSG00000109182 "Cell wall biogenesis 43 C-terminal homolog" Q9H720 4 48986275-49062081 "Predicted membrane proteins" "GPI-anchor biosynthesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 19.7;prostate: 40.2;skin 1: 24.1" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 83.0;Esophageal apical cells: 113.3;Esophageal suprabasal cells: 77.4;Fallopian tube ciliated cells: 79.0;Prostatic glandular cells: 236.6;Renal connecting tubule cells: 73.5;Respiratory ciliated cells: 51.7;Suprabasal keratinocytes: 62.7;Tuft cells: 46.1" "Cell type enriched" "Detected in some" 5 "ependymal cell: 8.8" "Group enriched" "Detected in many" 4 "Kidney Chromophobe (TCGA): 32.4;Prostate Adenocarcinoma (TCGA): 35.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 29 "prostate cancer: 16.8" "Colon - Colon enterocytes, Kidney - Intercalated cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Pituitary gland - Thyrotropes, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA042814, HPA048140" Uncertain Uncertain "Golgi apparatus,Plasma membrane" NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 60: Prostate cancer - Unknown function" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 1 "Golgi apparatus, Plasma membrane" "HPA042814: , HPA048140: " "unprognostic (2.22e-3)" "unprognostic (9.69e-2)" "unprognostic (3.34e-1)" "unprognostic (7.19e-2)" "potential prognostic favorable (3.76e-5)" "unprognostic (1.20e-1)" "unprognostic (2.10e-1)" "potential prognostic favorable (1.27e-7)" "unprognostic (2.73e-2)" "unprognostic (6.26e-2)" "unprognostic (3.71e-2)" "unprognostic (1.08e-1)" "unprognostic (1.49e-1)" "unprognostic (3.86e-2)" "unprognostic (2.11e-1)" "unprognostic (2.87e-2)" "unprognostic (1.13e-1)" CX3CL1 "ABCD-3, C3Xkine, CXC3, CXC3C, NTN, SCYD1" ENSG00000006210 "C-X3-C motif chemokine ligand 1" P78423 16 57372477-57385044 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Chemotaxis, Host-virus interaction, Inflammatory response" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast secretory cells: 132.7;Epididymal clear cells: 69.4;Epididymal efferent duct absorptive cells: 62.6;Lacrimal acinar cells: 59.8;Pancreatic duct cells: 77.8;Salivary duct cells: 71.3;Salivary myoepithelial cells: 53.3;Submucosal glandular cells: 65.4;Vascular endothelial cells: 92.8;Vascular smooth muscle cells: 55.7" "Cell type enhanced" "Detected in all" "vascular associated smooth muscle cell: 136.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026192, HPA040361, CAB080311" Approved Supported "Plasma membrane" "Secreted to blood" Chemokine NA NA 1870000 "Cluster 74: Non-specific - Signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 9 "Plasma membrane" "CAB026192: , CAB080311: , HPA040361: " "unprognostic (1.06e-1)" "unprognostic (8.24e-3)" "unprognostic (2.57e-1)" "unprognostic (1.32e-3)" "unprognostic (3.67e-2)" "unprognostic (2.90e-2)" "unprognostic (3.06e-1)" "unprognostic (1.49e-1)" "unprognostic (2.53e-1)" "unprognostic (2.03e-3)" "validated prognostic favorable (1.08e-8)" "validated prognostic favorable (1.92e-5)" "potential prognostic favorable (7.97e-6)" "unprognostic (4.94e-2)" "unprognostic (2.59e-1)" "unprognostic (2.83e-3)" "unprognostic (1.03e-1)" "unprognostic (2.16e-1)" "unprognostic (2.94e-1)" "unprognostic (1.63e-1)" "unprognostic (4.14e-2)" "unprognostic (3.66e-2)" "unprognostic (1.91e-2)" "unprognostic (3.05e-3)" "unprognostic (8.93e-2)" "unprognostic (8.37e-2)" "unprognostic (4.94e-2)" "unprognostic (1.45e-2)" "unprognostic (1.45e-1)" "unprognostic (4.44e-2)" "unprognostic (2.95e-2)" CX3CR1 "CCRL1, CMKBRL1, CMKDR1, GPR13, V28" ENSG00000168329 "C-X3-C motif chemokine receptor 1" P49238 3 39263495-39281735 "Disease related genes, G-protein coupled receptors, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity, Inflammatory response, Innate immunity" "G-protein coupled receptor, Receptor, Transducer" "Age-related macular degeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.1" "Cell type enriched" "Detected in some" 8 "Microglia: 936.8" "Cell type enriched" "Detected in many" 12 "central nervous system macrophage: 983.8" "Group enriched" "Detected in many" 4 "Glioblastoma Multiforme (TCGA): 39.8;Kidney Renal Clear Cell Carcinoma (TCGA): 11.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 451.3" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in some" 6 "Myeloma: 16.7" "Heart muscle - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032478, HPA046587" Approved Supported "Plasma membrane" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 73: Brain - Neuronal signaling" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" "Plasma membrane" "CAB032478: , HPA046587: " "unprognostic (8.51e-2)" "unprognostic (1.09e-1)" "unprognostic (9.40e-2)" "unprognostic (6.10e-2)" "unprognostic (3.66e-2)" "unprognostic (2.09e-1)" "potential prognostic favorable (7.39e-6)" "unprognostic (1.11e-3)" "unprognostic (3.88e-3)" "unprognostic (7.23e-2)" "unprognostic (1.82e-3)" "unprognostic (7.50e-2)" "unprognostic (3.23e-1)" "unprognostic (1.15e-3)" "unprognostic (4.55e-3)" "unprognostic (4.18e-2)" "unprognostic (7.69e-2)" "unprognostic (9.11e-2)" "unprognostic (1.77e-2)" "unprognostic (3.25e-2)" "unprognostic (1.53e-1)" "unprognostic (7.14e-3)" "unprognostic (8.43e-2)" CXADR CAR ENSG00000154639 "CXADR Ig-like cell adhesion molecule" P78310 21 17513043-17593579 "Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 50.3" "Cell type enhanced" "Detected in many" "Endometrial luminal cells: 393.9;Enterocytes: 530.9;Urothelial cells: 715.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003342, CAB005103, HPA030411, HPA030412" Enhanced Supported "Nucleoplasm,Plasma membrane,Cell Junctions" "Secreted - unknown location" Receptor NA NA 12000 "Cluster 77: Intestine - Digestion" "Cluster 30: White matter - Myelination" "Cluster 4: Non-specific - Transcription" "Cluster 69: Urothelial cells - Basic cellular functions" 11 "Plasma membrane, Cell Junctions" Nucleoplasm "CAB005103: , HPA003342: , HPA030411: , HPA030412: " "unprognostic (7.24e-3)" "unprognostic (2.20e-1)" "unprognostic (1.24e-3)" "unprognostic (1.24e-1)" "unprognostic (7.47e-2)" "unprognostic (7.62e-2)" "unprognostic (3.78e-2)" "unprognostic (1.25e-1)" "unprognostic (2.35e-3)" "unprognostic (1.25e-1)" "unprognostic (5.11e-2)" "unprognostic (9.38e-3)" "unprognostic (1.04e-1)" "unprognostic (1.14e-1)" "unprognostic (3.71e-2)" "unprognostic (6.35e-2)" "unprognostic (6.59e-2)" "unprognostic (1.79e-1)" "unprognostic (1.03e-1)" "unprognostic (5.57e-2)" "unprognostic (1.24e-1)" "unprognostic (1.18e-2)" "unprognostic (2.26e-1)" "unprognostic (7.23e-2)" "unprognostic (1.43e-2)" "unprognostic (1.12e-1)" "unprognostic (4.21e-1)" "unprognostic (4.62e-3)" "unprognostic (2.08e-1)" "unprognostic (3.23e-2)" "unprognostic (7.93e-3)" CXCL1 "FSP, GRO1, GROa, MGSA, MGSA-a, NAP-3, SCYB1" ENSG00000163739 "C-X-C motif chemokine ligand 1" P09341 4 73869393-73871308 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Inflammatory response" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 95.8;lymphoid tissue: 167.5" "Cell type enhanced" "Detected in many" "Cholangiocytes: 448.0;Conjunctival goblet cells: 554.4;Endometrial luminal cells: 370.0;Endometrial secretory cells: 2602.2;Epididymal basal cells: 2022.4;Esophageal apical cells: 572.4;Fallopian secretory cells: 634.4;Pancreatic duct cells: 1126.8;Respiratory secretory cells: 973.0" "Group enriched" "Detected in some" 19 "endothelial cell: 14.3;fibroblast: 6.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 244 "neutrophil: 47.5" "Lineage enriched" "Detected in single" 244 "granulocytes: 47.5" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Ductal cells" "Secreted to blood" Chemokine NA NA 384000 "Cluster 4: Neutrophils - Degranulation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 4 "unprognostic (9.01e-2)" "potential prognostic favorable (2.36e-4)" "unprognostic (4.97e-2)" "potential prognostic unfavorable (5.42e-4)" "unprognostic (2.49e-2)" "unprognostic (5.04e-2)" "unprognostic (1.43e-3)" "unprognostic (3.35e-3)" "potential prognostic unfavorable (3.81e-4)" "unprognostic (1.31e-1)" "potential prognostic unfavorable (2.00e-5)" "unprognostic (1.97e-2)" "unprognostic (1.84e-2)" "potential prognostic unfavorable (4.46e-4)" "unprognostic (2.51e-1)" "unprognostic (2.29e-1)" "unprognostic (1.10e-2)" "unprognostic (2.06e-1)" "unprognostic (1.65e-2)" "unprognostic (2.10e-1)" "unprognostic (2.38e-2)" "unprognostic (4.90e-2)" "potential prognostic unfavorable (3.67e-4)" "unprognostic (2.20e-3)" "unprognostic (3.91e-2)" "unprognostic (2.79e-2)" "unprognostic (3.34e-1)" "unprognostic (9.65e-2)" "unprognostic (8.05e-2)" "unprognostic (2.38e-2)" "unprognostic (1.84e-1)" CXCL10 "C7, crg-2, gIP-10, IFI10, INP10, IP-10, mob-1, SCYB10" ENSG00000169245 "C-X-C motif chemokine ligand 10" P02778 4 76021118-76023497 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 90.0" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 23.2;cDC: 35.5;Endometrial glandular cells: 19.7;Epididymal basal cells: 59.4;Epididymal clear cells: 89.8;Epididymal efferent duct ciliated cells: 177.1;Fallopian secretory cells: 75.6;Macrophages: 46.8;monocytes: 20.2" "Group enriched" "Detected in some" 12 "central nervous system macrophage: 3.2;endothelial cell: 8.0;fibroblast: 2.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "pons: 21.6" "Group enriched" "Detected in many" 11 "classical monocyte: 21.6;intermediate monocyte: 52.5;non-classical monocyte: 37.1" "Lineage enriched" "Detected in many" 15 "monocytes: 52.5" "Group enriched" "Detected in many" 6 "head and neck cancer: 8.1;lymphoma: 30.7" "Thyroid gland - T-cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "Secreted to blood" Chemokine NA NA 253000 "Cluster 40: Monocytes - Innate immune response" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 4 "unprognostic (2.94e-2)" "unprognostic (1.32e-1)" "unprognostic (3.78e-1)" "unprognostic (2.32e-1)" "unprognostic (8.24e-2)" "unprognostic (9.69e-2)" "unprognostic (2.84e-1)" "unprognostic (1.20e-1)" "unprognostic (3.90e-2)" "unprognostic (7.78e-2)" "unprognostic (5.18e-2)" "unprognostic (1.99e-1)" "potential prognostic unfavorable (6.04e-4)" "unprognostic (1.50e-1)" "unprognostic (8.21e-3)" "unprognostic (1.76e-1)" "unprognostic (1.16e-1)" "unprognostic (3.13e-1)" "unprognostic (2.93e-1)" "potential prognostic favorable (7.63e-4)" "unprognostic (7.29e-2)" "potential prognostic unfavorable (3.36e-4)" "unprognostic (2.19e-1)" "unprognostic (1.35e-1)" "unprognostic (1.86e-1)" "unprognostic (5.16e-3)" "unprognostic (5.23e-2)" "unprognostic (1.26e-1)" "unprognostic (5.64e-2)" "unprognostic (1.64e-2)" "unprognostic (5.13e-2)" CXCL11 "b-R1, H174, I-TAC, IP-9, SCYB11, SCYB9B" ENSG00000169248 "C-X-C motif chemokine ligand 11" O14625 4 76033682-76041415 "Human disease related genes, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 11.1" "Cell type enhanced" "Detected in some" "Epididymal basal cells: 8.4;Epididymal efferent duct ciliated cells: 33.6;Fallopian secretory cells: 16.1;Foveolar cells: 5.8;Megakaryocytes: 18.5;Pancreatic acinar cells: 8.1;Vascular endothelial cells: 4.4" "Cell type enriched" "Detected in single" 13 "endothelial cell: 3.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 6.2;head and neck cancer: 10.0" "Adipose visceral - T-cells" "Region enhanced" "Detected in single" "spinal cord: 1.7" CAB009921 Uncertain "Secreted to blood" Chemokine NA NA 187000 "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 5 "CAB009921: " "unprognostic (1.97e-1)" "unprognostic (2.64e-1)" "unprognostic (2.48e-1)" "unprognostic (1.79e-1)" "unprognostic (1.11e-1)" "unprognostic (4.21e-2)" "unprognostic (1.86e-1)" "unprognostic (2.83e-2)" "unprognostic (9.95e-2)" "unprognostic (7.75e-2)" "unprognostic (1.86e-1)" "unprognostic (1.26e-1)" "unprognostic (3.32e-1)" "unprognostic (1.01e-1)" "unprognostic (1.15e-1)" "unprognostic (8.90e-2)" "unprognostic (2.40e-1)" "unprognostic (7.14e-2)" "potential prognostic favorable (2.54e-6)" "unprognostic (1.23e-2)" "potential prognostic unfavorable (7.21e-4)" "unprognostic (1.49e-1)" "unprognostic (1.85e-1)" "unprognostic (8.92e-2)" "potential prognostic favorable (8.25e-4)" "unprognostic (3.20e-1)" "unprognostic (1.46e-1)" "unprognostic (2.48e-2)" "unprognostic (4.47e-2)" "unprognostic (1.84e-1)" CXCL12 "PBSF, SCYB12, SDF-1a, SDF-1b, SDF1, SDF1A, SDF1B, TLSF-a, TLSF-b, TPAR1" ENSG00000107562 "C-X-C motif chemokine ligand 12" P48061 10 44370165-44386493 "Predicted secreted proteins" "Chemotaxis, Host-virus interaction" "Cytokine, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 88.0;Fibro-adipogenic progenitors: 85.7;Fibroblasts: 323.2;Hepatic stellate cells: 348.6;Kupffer cells: 603.7;Macrophages: 82.2;Pancreatic acinar cells: 84.2;Pericytes: 190.0;Vascular endothelial cells: 136.0" "Cell type enhanced" "Detected in many" "endothelial cell: 96.7;fibroblast: 282.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 60.3;testis cancer: 57.1" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblasts_2, Minor Salivary Gland - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB017564 Approved "Secreted to blood" Chemokine NA NA 1030000 1700000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 8: Immune cells - Immune response" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 22 "CAB017564: " "unprognostic (1.41e-1)" "unprognostic (8.79e-2)" "unprognostic (4.07e-3)" "unprognostic (4.71e-3)" "unprognostic (1.47e-1)" "unprognostic (1.49e-1)" "unprognostic (1.49e-2)" "unprognostic (2.13e-1)" "unprognostic (9.38e-2)" "unprognostic (3.25e-1)" "potential prognostic favorable (4.45e-4)" "unprognostic (2.41e-2)" "unprognostic (1.47e-1)" "unprognostic (5.31e-2)" "potential prognostic favorable (3.07e-5)" "unprognostic (4.90e-3)" "unprognostic (1.03e-1)" "unprognostic (1.84e-2)" "unprognostic (2.99e-1)" "unprognostic (4.44e-3)" "unprognostic (1.11e-2)" "unprognostic (1.87e-1)" "unprognostic (1.85e-1)" "unprognostic (6.18e-2)" "unprognostic (4.98e-1)" "unprognostic (8.70e-2)" "unprognostic (3.73e-2)" "unprognostic (6.69e-2)" "unprognostic (3.05e-1)" "unprognostic (9.31e-2)" "unprognostic (7.51e-2)" CXCL13 "ANGIE, ANGIE2, BCA-1, BLC, BLR1L, SCYB13" ENSG00000156234 "C-X-C motif chemokine ligand 13" O43927 4 77511753-77611834 "Cancer-related genes, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 15 "lymphoid tissue: 505.6" "Group enriched" "Detected in many" 4 "Breast hormone-responsive cells: 509.4;Decidual stromal cells: 212.2" "Cell type enhanced" "Detected in some" "upper rhombic lip: 15.6" "Cancer enhanced" "Detected in many" "Lung Squamous Cell Carcinoma (TCGA): 120.6" "Region enhanced" "Detected in single" "medulla oblongata: 2.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "lymphoma: 5.1;thyroid cancer: 9.7" "Spleen - Fibroblasts_2, Thyroid gland - Plasma cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA052613 Uncertain "Secreted to blood" Chemokine NA NA 93700 "Cluster 18: Lymphoid tissue - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 9: T-cells - Adaptive immunity: Regulation" "HPA052613: " "unprognostic (8.08e-2)" "unprognostic (9.40e-3)" "unprognostic (1.07e-2)" "unprognostic (1.98e-3)" "unprognostic (7.53e-2)" "unprognostic (1.67e-1)" "potential prognostic unfavorable (9.30e-4)" "unprognostic (2.05e-2)" "potential prognostic favorable (4.02e-4)" "potential prognostic unfavorable (3.85e-5)" "unprognostic (3.28e-2)" "potential prognostic unfavorable (5.74e-5)" "unprognostic (1.06e-1)" "unprognostic (2.13e-2)" "unprognostic (2.29e-2)" "unprognostic (4.66e-2)" "unprognostic (1.22e-1)" "unprognostic (2.43e-1)" "potential prognostic favorable (7.21e-4)" "unprognostic (4.21e-3)" "unprognostic (1.11e-1)" "unprognostic (5.66e-2)" "unprognostic (4.70e-1)" "unprognostic (2.57e-3)" "unprognostic (3.82e-3)" "unprognostic (3.48e-2)" "unprognostic (3.55e-2)" "unprognostic (1.40e-1)" "unprognostic (1.54e-1)" "unprognostic (5.68e-2)" CXCL14 "BMAC, bolekine, BRAK, Kec, KS1, MIP-2g, NJAC, SCYB14" ENSG00000145824 "C-X-C motif chemokine ligand 14" O95715 5 135570679-135579279 "Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 767.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 3039.6;Breast myoepithelial cells: 3978.2;Endometrial glandular cells: 2010.8;Epididymal basal cells: 3395.5;Epididymal efferent duct absorptive cells: 2855.6;Esophageal basal cells: 792.3;Fibroblasts: 1464.9;Ocular epithelial cells: 1631.4;Pituicytes/FSCs: 1723.1;Suprabasal keratinocytes: 1051.7" "Cell type enriched" "Detected in many" 15 "CGE interneuron: 1651.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 150.2;head and neck cancer: 209.2" "Breast - Breast myoepithelial cells, Kidney - Proximal tubular cells, Lung - Fibroblasts_2, Pancreas - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB029996 Uncertain "Secreted to blood" Chemokine NA NA 800000 "Cluster 9: Skin - Hair follicle development" "Cluster 53: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 108: Fibroblasts - ECM organization" 6 "CAB029996: " "unprognostic (1.84e-2)" "unprognostic (1.60e-3)" "unprognostic (1.66e-1)" "potential prognostic favorable (2.83e-4)" "unprognostic (5.60e-3)" "unprognostic (7.20e-2)" "unprognostic (1.56e-3)" "potential prognostic unfavorable (9.69e-4)" "unprognostic (1.43e-2)" "unprognostic (2.33e-2)" "potential prognostic favorable (1.16e-5)" "unprognostic (2.36e-3)" "unprognostic (1.31e-2)" "unprognostic (7.15e-2)" "unprognostic (3.31e-2)" "unprognostic (2.65e-1)" "unprognostic (1.38e-1)" "unprognostic (3.83e-2)" "unprognostic (1.96e-1)" "unprognostic (3.11e-2)" "potential prognostic unfavorable (1.75e-4)" "unprognostic (9.82e-2)" "unprognostic (5.14e-3)" "unprognostic (4.82e-2)" "unprognostic (1.45e-1)" "unprognostic (2.65e-2)" "unprognostic (3.60e-2)" "unprognostic (3.79e-1)" "unprognostic (1.89e-1)" "unprognostic (1.98e-1)" "unprognostic (1.32e-1)" CXCL16 "CXCLG16, SR-PSOX, SRPSOX" ENSG00000161921 "C-X-C motif chemokine ligand 16" Q9H2A7 17 4733533-4739928 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 7 "Late spermatids: 6883.4" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 65.8;ependymal cell: 26.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 63.2;intermediate monocyte: 107.3;myeloid DC: 38.2;neutrophil: 103.3;non-classical monocyte: 141.8" "Group enriched" "Detected in many" 7 "dendritic cells: 38.2;granulocytes: 103.3;monocytes: 141.8" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Ductal cells, Spleen - Macrophages, Testis - Late spermatids, Thyroid gland - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA053253, HPA066315" Approved Approved "Golgi apparatus,Vesicles" "Secreted to blood" Chemokine NA NA 1100000 21000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 47: Testis - Mixed function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 4 "Golgi apparatus, Vesicles" "HPA053253: , HPA066315: " "unprognostic (1.16e-2)" "potential prognostic favorable (7.87e-4)" "unprognostic (2.52e-1)" "unprognostic (3.32e-1)" "unprognostic (1.74e-1)" "unprognostic (2.24e-1)" "unprognostic (1.25e-1)" "potential prognostic unfavorable (8.79e-5)" "unprognostic (1.07e-1)" "unprognostic (8.57e-2)" "unprognostic (2.58e-1)" "unprognostic (1.18e-1)" "unprognostic (8.28e-3)" "unprognostic (1.70e-2)" "unprognostic (1.02e-1)" "unprognostic (1.42e-1)" "unprognostic (3.19e-2)" "unprognostic (1.41e-1)" "unprognostic (1.03e-1)" "unprognostic (2.67e-1)" "unprognostic (1.29e-1)" "unprognostic (1.41e-1)" "unprognostic (5.23e-3)" "unprognostic (3.07e-1)" "unprognostic (2.36e-1)" "unprognostic (3.71e-1)" "unprognostic (8.75e-2)" "unprognostic (3.09e-1)" "unprognostic (3.38e-2)" "unprognostic (2.76e-2)" "unprognostic (6.40e-2)" CXCL17 "Dcip1, DMC, UNQ473, VCC1" ENSG00000189377 "C-X-C motif chemokine ligand 17" Q6UXB2 19 42428278-42442946 "Predicted secreted proteins" "Angiogenesis, Chemotaxis, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 125.8;lung: 140.3;salivary gland: 146.4;stomach 1: 338.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 652.7;Conjunctival goblet cells: 1282.5;Esophageal apical cells: 2922.2;Esophageal suprabasal cells: 705.0;Gastric chief cells: 1910.0;Lacrimal acinar cells: 619.6;Mucous neck cells: 516.0;Ocular epithelial cells: 528.2;Parietal cells: 1113.8;Respiratory deuterosomal cells: 863.5;Respiratory secretory cells: 1435.5;Submucosal glandular cells: 945.0;Transitional alveolar cells: 562.8" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 295.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 17.2;Gastric cancer: 8.7;lung cancer: 8.6" "Lung - Alveolar cells type 2, Prostate - Urothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Secreted to blood" "Developmental protein" NA NA 400000000 53000 "Cluster 82: Salivary gland - Secretion" "Cluster 34: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 3 "unprognostic (7.98e-3)" "unprognostic (2.04e-1)" "unprognostic (6.64e-3)" "unprognostic (7.92e-2)" "unprognostic (2.99e-1)" "unprognostic (6.62e-2)" "unprognostic (8.59e-3)" "unprognostic (1.69e-1)" "unprognostic (3.61e-1)" "unprognostic (2.30e-2)" "potential prognostic favorable (3.44e-6)" "unprognostic (5.13e-2)" "unprognostic (2.26e-1)" "unprognostic (3.01e-3)" "unprognostic (2.56e-1)" "unprognostic (3.74e-1)" "potential prognostic unfavorable (2.49e-4)" "unprognostic (1.23e-2)" "unprognostic (1.07e-1)" "unprognostic (5.88e-1)" "unprognostic (4.06e-2)" "unprognostic (1.01e-1)" "unprognostic (1.53e-1)" "unprognostic (3.56e-2)" "unprognostic (2.12e-2)" CXCL2 "CINC-2a, GRO2, GROb, MGSA-b, MIP-2a, SCYB2" ENSG00000081041 "C-X-C motif chemokine ligand 2" P19875 4 74097040-74099196 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 537.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 1290.9;Breast lactating cells: 2403.0;Breast secretory cells: 1912.1;Endometrial glandular cells: 1055.7;Endometrial luminal cells: 1392.2;Endometrial secretory cells: 1173.6;Epididymal basal cells: 4366.7;Epididymal efferent duct absorptive cells: 3570.9;Fallopian secretory cells: 1778.6;monocytes: 1421.2;Pancreatic duct cells: 974.2" "Cell type enriched" "Detected in some" 5 "endothelial cell: 89.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "intermediate monocyte: 1.1;non-classical monocyte: 1.1" "Lineage enriched" "Detected in single" 10 "monocytes: 1.1" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Ductal cells" "Secreted to blood" Chemokine NA NA 500000 "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 5 "unprognostic (6.25e-2)" "validated prognostic favorable (7.80e-5)" "validated prognostic favorable (1.70e-4)" "potential prognostic unfavorable (2.67e-5)" "unprognostic (1.42e-2)" "unprognostic (9.33e-2)" "potential prognostic unfavorable (8.96e-4)" "unprognostic (1.07e-1)" "unprognostic (5.05e-2)" "unprognostic (9.30e-2)" "potential prognostic unfavorable (2.08e-5)" "unprognostic (3.32e-2)" "unprognostic (1.23e-2)" "unprognostic (1.10e-2)" "unprognostic (2.86e-3)" "unprognostic (1.08e-1)" "unprognostic (1.09e-1)" "unprognostic (1.13e-2)" "unprognostic (2.44e-1)" "unprognostic (3.25e-1)" "unprognostic (5.38e-3)" "unprognostic (1.29e-1)" "unprognostic (7.52e-2)" "unprognostic (5.21e-2)" "unprognostic (1.31e-2)" "potential prognostic favorable (7.37e-5)" "unprognostic (1.14e-1)" "unprognostic (3.49e-2)" "unprognostic (1.62e-1)" "unprognostic (1.68e-1)" "unprognostic (3.37e-1)" CXCL3 "CINC-2b, GRO3, GROg, MIP-2b, SCYB3" ENSG00000163734 "C-X-C motif chemokine ligand 3" P19876 4 74036589-74038807 "Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 19.5;cervix: 19.4" "Cell type enhanced" "Detected in many" "cDC: 806.9;Endometrial secretory cells: 473.8;Epididymal basal cells: 1166.6;Epididymal efferent duct absorptive cells: 467.9;Fallopian secretory cells: 315.4;Gastric progenitor cells: 351.2;Macrophages: 638.1;monocytes: 1377.5;Salivary basal cells: 306.4" "Cell type enriched" "Detected in some" 4 "endothelial cell: 25.5" "Group enriched" "Detected in many" 4 "Colon Adenocarcinoma (TCGA): 48.2;Rectum Adenocarcinoma (TCGA): 40.0;Stomach Adenocarcinoma (TCGA): 43.8" "Group enriched" "Detected in some" 6 "cerebral cortex: 4.0;thalamus: 5.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Ductal cells" "Secreted to blood" Chemokine NA NA 28700 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 4 "unprognostic (1.34e-3)" "unprognostic (9.32e-3)" "potential prognostic unfavorable (7.47e-5)" "unprognostic (8.19e-3)" "unprognostic (1.98e-2)" "unprognostic (1.98e-2)" "unprognostic (4.24e-2)" "unprognostic (4.62e-2)" "unprognostic (1.04e-1)" "unprognostic (8.15e-2)" "unprognostic (1.90e-1)" "unprognostic (1.59e-1)" "unprognostic (9.14e-2)" "unprognostic (1.39e-1)" "unprognostic (1.82e-1)" "unprognostic (3.31e-1)" "unprognostic (1.49e-2)" "unprognostic (2.65e-2)" "unprognostic (4.96e-2)" "unprognostic (7.53e-2)" "unprognostic (1.98e-3)" "unprognostic (1.25e-2)" "unprognostic (1.18e-1)" "unprognostic (4.86e-3)" "unprognostic (1.99e-1)" CXCL5 "ENA-78, SCYB5" ENSG00000163735 "C-X-C motif chemokine ligand 5" P42830 4 73995642-73998677 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "lymphoid tissue: 33.9;salivary gland: 56.3" "Cell type enhanced" "Detected in some" "Endometrial secretory cells: 56.1;Foveolar cells: 22.2;Gastric progenitor cells: 57.7;Macrophages: 25.1;Megakaryocytes: 37.1;monocytes: 102.3;Mucous neck cells: 67.9;Platelets: 150.4;Salivary acinar cells: 47.8" "Cell type enhanced" "Detected in some" "ependymal cell: 5.9;lower rhombic lip: 2.6" "Cancer enhanced" "Detected in many" "Pancreatic Adenocarcinoma (TCGA): 84.5;Stomach Adenocarcinoma (TCGA): 109.5" "Region enhanced" "Detected in many" "cerebral cortex: 19.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "pancreatic cancer: 162.1" "Testis - Spermatogonia" HPA065474 Approved Approved Vesicles "Secreted to blood" Chemokine NA NA 1110000 93000 "Cluster 5: Spleen - Immune response" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 5 Vesicles "HPA065474: " "unprognostic (8.93e-2)" "unprognostic (7.55e-3)" "unprognostic (6.56e-2)" "potential prognostic unfavorable (4.41e-4)" "unprognostic (3.25e-2)" "unprognostic (1.75e-1)" "validated prognostic unfavorable (9.97e-4)" "validated prognostic unfavorable (3.86e-4)" "unprognostic (1.60e-1)" "potential prognostic unfavorable (2.93e-6)" "unprognostic (2.78e-2)" "unprognostic (1.01e-2)" "potential prognostic unfavorable (1.48e-4)" "unprognostic (1.31e-1)" "unprognostic (4.22e-2)" "unprognostic (2.84e-1)" "unprognostic (3.26e-2)" "unprognostic (2.55e-2)" "unprognostic (7.52e-2)" "unprognostic (2.47e-1)" "potential prognostic unfavorable (6.69e-4)" "unprognostic (7.95e-2)" "unprognostic (1.06e-1)" "unprognostic (2.62e-2)" "unprognostic (1.50e-1)" "unprognostic (1.22e-1)" "unprognostic (3.42e-1)" "unprognostic (1.80e-1)" CXCL6 "CKA-3, GCP-2, SCYB6" ENSG00000124875 "C-X-C motif chemokine ligand 6" P80162 4 73836640-73849064 "Predicted secreted proteins" Chemotaxis "Antibiotic, Antimicrobial, Cytokine, Heparin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "gallbladder: 33.9;lymphoid tissue: 95.0;urinary bladder: 24.8" "Cell type enhanced" "Detected in some" "Cholangiocytes: 329.3;Conjunctival goblet cells: 76.7;Endometrial secretory cells: 160.4;Pancreatic duct cells: 66.8;Prostatic club cells: 112.3;Prostatic hillock cells: 45.6;Respiratory basal cells: 57.5;Respiratory deuterosomal cells: 261.2;Respiratory secretory cells: 316.9" "Cell type enriched" "Detected in single" 4 "fibroblast: 2.9" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 39.9" "Group enriched" "Detected in many" 4 "cerebral cortex: 9.7;choroid plexus: 4.9" "Immune cell enriched" "Detected in single" 105 "neutrophil: 10.4" "Lineage enriched" "Detected in single" 105 "granulocytes: 10.4" "Group enriched" "Detected in many" 10 "Kidney cancer: 181.9;thyroid cancer: 141.4" "Adipose visceral - Mesothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Ductal cells, Testis - Spermatogonia" "Region enhanced" "Detected in many" "basal ganglia: 9.6" "Not detected" "Not detected" "Secreted to blood" Chemokine NA NA 108000 "Cluster 4: Neutrophils - Degranulation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 3 "unprognostic (4.87e-2)" "unprognostic (1.70e-1)" "unprognostic (4.03e-3)" "unprognostic (2.87e-1)" "unprognostic (2.84e-1)" "unprognostic (1.57e-3)" "unprognostic (4.77e-2)" "unprognostic (1.19e-1)" "potential prognostic unfavorable (3.36e-4)" "unprognostic (3.69e-3)" "unprognostic (4.30e-2)" "unprognostic (1.61e-3)" "unprognostic (4.71e-1)" "unprognostic (1.19e-2)" "unprognostic (2.85e-1)" "unprognostic (1.32e-1)" "unprognostic (2.61e-1)" "unprognostic (1.56e-1)" "unprognostic (3.11e-1)" "unprognostic (2.73e-2)" "potential prognostic unfavorable (7.23e-5)" "unprognostic (1.32e-1)" "unprognostic (5.80e-3)" "unprognostic (1.64e-1)" "unprognostic (5.21e-1)" "unprognostic (3.59e-1)" "unprognostic (3.82e-2)" CXCL8 "3-10C, AMCF-I, b-ENAP, GCP-1, GCP1, IL-8, IL8, K60, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1, SCYB8, TSG-1" ENSG00000169429 "C-X-C motif chemokine ligand 8" P10145 4 73740519-73743716 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "bone marrow: 2989.3" "Cell type enhanced" "Detected in many" "cDC: 5291.0;Endometrial glandular cells: 1898.1;Endometrial secretory cells: 2945.1;Epididymal basal cells: 12468.0;Epididymal efferent duct absorptive cells: 2558.5;Macrophages: 2070.2;monocytes: 3941.4;Neutrophils: 6690.9" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 2.4;endothelial cell: 9.7;fibroblast: 3.7" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 10 "cerebral cortex: 274.2" "Immune cell enriched" "Detected in some" 408 "neutrophil: 439.6" "Lineage enriched" "Detected in single" 1040 "granulocytes: 439.6" "Cancer enhanced" "Detected in many" "Kidney cancer: 314.5" "Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Ductal cells" "Not detected" "Not detected" HPA057179 Supported Approved "Golgi apparatus" "Secreted to blood" Chemokine NA NA 7260 "Cluster 4: Neutrophils - Degranulation" "Cluster 15: Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 6 "Golgi apparatus" "HPA057179: " "unprognostic (3.23e-1)" "unprognostic (9.00e-2)" "potential prognostic unfavorable (6.85e-7)" "unprognostic (1.88e-2)" "unprognostic (5.06e-2)" "unprognostic (2.03e-2)" "unprognostic (1.31e-3)" "unprognostic (2.08e-3)" "unprognostic (4.40e-2)" "potential prognostic unfavorable (6.21e-4)" "unprognostic (4.03e-3)" "unprognostic (1.09e-1)" "potential prognostic unfavorable (1.31e-5)" "unprognostic (2.84e-2)" "unprognostic (1.69e-3)" "unprognostic (1.91e-2)" "unprognostic (4.43e-2)" "unprognostic (1.39e-1)" "unprognostic (3.04e-2)" "unprognostic (1.21e-2)" "unprognostic (2.77e-2)" "unprognostic (1.44e-1)" "unprognostic (4.09e-1)" "unprognostic (1.16e-1)" "unprognostic (3.43e-1)" "unprognostic (6.43e-2)" "unprognostic (6.63e-2)" "unprognostic (1.95e-2)" "unprognostic (2.11e-1)" CXCL9 "CMK, crg-10, Humig, MIG, SCYB9" ENSG00000138755 "C-X-C motif chemokine ligand 9" Q07325 4 76001275-76007509 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "lymphoid tissue: 290.0" "Cell type enhanced" "Detected in some" "cDC: 39.6;Cholangiocytes: 29.5;Kupffer cells: 7.2;Macrophages: 25.8;monocytes: 7.7;Pericytes: 10.1;Undifferentiated spermatogonia: 14.9;Vascular endothelial cells: 5.4" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in some" 6 "medulla oblongata: 3.8;pons: 3.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Rhabdoid: 1.8" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to blood" Chemokine NA NA 902000 "Cluster 18: Lymphoid tissue - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 82: Dendritic cells - Antigen presentation" 45 "unprognostic (1.61e-1)" "potential prognostic favorable (8.32e-4)" "unprognostic (2.10e-1)" "unprognostic (1.32e-2)" "unprognostic (8.84e-2)" "unprognostic (8.41e-2)" "unprognostic (1.40e-1)" "unprognostic (2.28e-2)" "unprognostic (3.90e-3)" "unprognostic (4.03e-1)" "unprognostic (3.85e-3)" "unprognostic (6.51e-2)" "unprognostic (4.06e-2)" "unprognostic (1.02e-1)" "unprognostic (4.94e-3)" "unprognostic (6.54e-2)" "unprognostic (1.65e-1)" "unprognostic (7.06e-2)" "unprognostic (1.48e-1)" "unprognostic (7.43e-3)" "unprognostic (3.85e-2)" "unprognostic (5.49e-3)" "unprognostic (1.98e-1)" "unprognostic (2.23e-1)" "unprognostic (1.14e-1)" "unprognostic (3.99e-3)" "unprognostic (1.91e-2)" "unprognostic (4.78e-2)" "unprognostic (7.33e-2)" "unprognostic (5.74e-3)" "unprognostic (2.00e-2)" CXCR1 "CD181, CDw128a, CKR-1, CMKAR1, IL8RA" ENSG00000163464 "C-X-C motif chemokine receptor 1" P25024 2 218162841-218166962 "Cancer-related genes, CD markers, G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 12.3;lymphoid tissue: 38.8" "Cell type enriched" "Detected in some" 14 "Neutrophils: 413.1" "Cell type enriched" "Detected in single" 25 "leukocyte: 2.5" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 14 "neutrophil: 1477.6" "Lineage enriched" "Detected in many" 62 "granulocytes: 1477.6" "Not detected" "Not detected" "Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophils_2, Pituitary gland - Neutrophils, Skeletal muscle - Neutrophils, Spleen - Neutrophils_2, Stomach - Neutrophils, Thyroid gland - Neutrophils" "Not detected" "Not detected" HPA031991 Uncertain NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 49: HMC-1 - Innate immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 4 "HPA031991: " "unprognostic (8.16e-2)" "unprognostic (6.79e-2)" "unprognostic (2.02e-1)" "unprognostic (2.13e-1)" "unprognostic (1.86e-1)" "unprognostic (1.20e-1)" "unprognostic (1.85e-1)" "unprognostic (1.28e-1)" "unprognostic (6.53e-2)" CXCR2 "CD182, CMKAR2, IL8RB" ENSG00000180871 "C-X-C motif chemokine receptor 2" P25025 2 218125289-218137251 "Cancer-related genes, CD markers, Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 25.7;lymphoid tissue: 40.8" "Cell type enriched" "Detected in some" 13 "Neutrophils: 1412.1" "Group enriched" "Detected in some" 14 "central nervous system macrophage: 1.3;leukocyte: 4.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 52 "neutrophil: 3297.5" "Lineage enriched" "Detected in many" 109 "granulocytes: 3297.5" "Cancer enriched" "Detected in single" 9 "Leukemia: 6.9" "Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Lung - Neutrophils_2, Prostate - Urothelial cells, Skeletal muscle - Neutrophils, Spleen - Neutrophils_2, Stomach - Neutrophils, Thyroid gland - Neutrophils" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB016268, HPA031999, HPA032017, CAB080545" Enhanced Approved "Vesicles,Plasma membrane,Microtubules,Mitotic spindle,Primary cilium,Primary cilium tip,Basal body" Yes NA "Cluster 35: Neutrophils - Protein binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 13 "Plasma membrane" "Vesicles, Microtubules, Mitotic spindle, Primary cilium, Primary cilium tip, Basal body" "CAB016268: , CAB080545: , HPA031999: , HPA032017: " "unprognostic (1.85e-2)" "unprognostic (2.82e-3)" "unprognostic (2.27e-2)" "unprognostic (3.32e-2)" "unprognostic (9.35e-3)" "unprognostic (7.78e-2)" "unprognostic (3.08e-1)" "unprognostic (1.12e-1)" "unprognostic (1.16e-2)" "unprognostic (1.71e-1)" "unprognostic (7.00e-3)" "unprognostic (8.57e-2)" "unprognostic (1.35e-1)" "unprognostic (4.02e-1)" "unprognostic (1.98e-1)" "unprognostic (2.39e-2)" "unprognostic (1.39e-1)" "unprognostic (5.72e-2)" CXCR3 "CD183, CKR-L2, CMKAR3, GPR9, IP10-R, MigR" ENSG00000186810 "C-X-C motif chemokine receptor 3" P49682 X 71615916-71618511 "CD markers, G-protein coupled receptors, Predicted membrane proteins" "Angiogenesis, Apoptosis, Chemotaxis" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.8;intestine: 6.0;lymphoid tissue: 15.3" "Group enriched" "Detected in some" 5 "pDCs: 110.1;T-cells: 40.1" "Cell type enriched" "Detected in single" 212 "leukocyte: 32.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 307.2" "Group enriched" "Detected in many" 5 "dendritic cells: 307.2;NK-cells: 199.6;T-cells: 124.7" "Cancer enhanced" "Detected in some" "colorectal cancer: 3.3;lymphoma: 9.3;Myeloma: 3.7" "Adipose subcutaneous - T-cells, Liver - T-cells, Lung - T-cells, Pancreas - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Skin - T-cells, Stomach - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA045942 Enhanced NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 9: T-cells - Adaptive immunity: Regulation" 4 "HPA045942: " "unprognostic (3.09e-2)" "unprognostic (1.42e-3)" "unprognostic (4.52e-2)" "unprognostic (2.91e-3)" "unprognostic (1.29e-1)" "unprognostic (3.93e-1)" "potential prognostic favorable (7.61e-4)" "unprognostic (1.13e-1)" "unprognostic (8.38e-2)" "unprognostic (1.97e-2)" "unprognostic (1.51e-2)" "unprognostic (4.06e-2)" "unprognostic (1.73e-2)" "unprognostic (7.54e-2)" "unprognostic (3.90e-1)" "unprognostic (1.73e-1)" "unprognostic (1.35e-1)" "unprognostic (6.43e-3)" "unprognostic (2.50e-2)" "unprognostic (1.16e-2)" "unprognostic (2.17e-1)" "unprognostic (2.69e-2)" "unprognostic (9.23e-2)" "potential prognostic favorable (7.53e-5)" "unprognostic (5.04e-2)" "unprognostic (4.51e-1)" "unprognostic (6.07e-2)" "unprognostic (1.92e-1)" CXCR4 "CD184, D2S201E, fusin, HM89, HSY3RR, LESTR, NPY3R, NPYR, NPYY3R" ENSG00000121966 "C-X-C motif chemokine receptor 4" P61073 2 136114349-136119177 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "Host-virus interaction" "G-protein coupled receptor, Host cell receptor for virus entry, Receptor, Transducer" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 1175.0;lymphoid tissue: 523.2" "Cell type enhanced" "Detected in many" "B-cells: 1506.7;cDC: 461.8;Innate lymphoid cells: 1589.7;Macrophages: 338.5;Monocyte progenitors: 374.5;monocytes: 309.5;Neutrophils: 1114.9;NK-cells: 959.7;pDCs: 456.8;Plasma cells: 333.1;T-cells: 1587.5;Thymocytes: 438.7" "Cell type enriched" "Detected in some" 6 "leukocyte: 200.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Leukemia: 190.2;lymphoma: 270.2;Myeloma: 151.1" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Prostate - T-cells, Skin - T-cells, Spleen - B-cells (Spleen), Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 15: Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 15 "unprognostic (1.64e-2)" "unprognostic (1.41e-1)" "unprognostic (2.80e-1)" "unprognostic (8.28e-3)" "unprognostic (2.12e-1)" "unprognostic (1.77e-1)" "unprognostic (9.34e-3)" "unprognostic (2.36e-3)" "unprognostic (7.14e-3)" "unprognostic (6.67e-2)" "unprognostic (1.06e-1)" "unprognostic (9.64e-2)" "unprognostic (3.84e-2)" "unprognostic (2.90e-2)" "unprognostic (3.59e-1)" "unprognostic (5.95e-3)" "unprognostic (1.32e-1)" "unprognostic (2.09e-1)" "unprognostic (1.43e-1)" "unprognostic (2.69e-3)" "unprognostic (2.99e-1)" "unprognostic (2.23e-1)" "unprognostic (8.50e-2)" "unprognostic (1.34e-1)" "unprognostic (1.37e-2)" "unprognostic (5.13e-3)" "unprognostic (3.81e-1)" "unprognostic (1.11e-3)" "unprognostic (8.57e-2)" "unprognostic (1.74e-1)" "unprognostic (1.72e-1)" CXCR5 "BLR1, CD185, MDR15" ENSG00000160683 "C-X-C motif chemokine receptor 5" P32302 11 118883892-118897787 "CD markers, G-protein coupled receptors, Predicted membrane proteins" "B-cell activation" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 12.6;lymphoid tissue: 29.3" "Group enriched" "Detected in some" 5 "B-cells: 108.5;Cardiomyocytes: 44.8;Epicardial cells: 70.5" "Cell type enriched" "Detected in single" 8 "leukocyte: 2.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "memory B-cell: 67.9;naive B-cell: 92.5" "Lineage enriched" "Detected in many" 8 "B-cells: 92.5" "Cancer enriched" "Detected in some" 12 "lymphoma: 36.0" "Spleen - B-cells (Spleen)" "Not detected" "Not detected" "Not detected" "Not detected" "CAB026149, HPA042432" Enhanced NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 3 "CAB026149: , HPA042432: " "unprognostic (4.25e-3)" "unprognostic (6.82e-2)" "unprognostic (3.64e-3)" "unprognostic (1.88e-1)" "potential prognostic unfavorable (2.17e-4)" "unprognostic (1.42e-1)" "unprognostic (8.82e-2)" "unprognostic (8.64e-2)" "unprognostic (5.76e-2)" "potential prognostic unfavorable (1.18e-6)" "unprognostic (6.21e-2)" "unprognostic (3.35e-1)" "unprognostic (8.06e-2)" "unprognostic (4.18e-2)" "unprognostic (1.25e-1)" "unprognostic (8.59e-2)" "unprognostic (1.52e-1)" "unprognostic (1.96e-1)" "potential prognostic favorable (2.38e-4)" "unprognostic (1.05e-1)" "unprognostic (2.61e-1)" "unprognostic (3.85e-1)" "unprognostic (8.44e-3)" "unprognostic (8.06e-2)" "unprognostic (9.91e-2)" "unprognostic (7.79e-2)" "unprognostic (1.54e-1)" "unprognostic (4.31e-1)" "unprognostic (4.38e-2)" CXCR6 "BONZO, CD186, STRL33, TYMSTR" ENSG00000172215 "C-X-C motif chemokine receptor 6" O00574 3 45940933-45948351 "CD markers, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 16.0" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 50.7;Extravillous trophoblasts: 113.2;Innate lymphoid cells: 27.4;Migrating cytotrophoblasts: 38.3;NK-cells: 28.3;T-cells: 86.7" "Cell type enriched" "Detected in some" 25 "leukocyte: 34.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 446.5" "Lineage enriched" "Detected in many" 5 "T-cells: 446.5" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 2.1" "Lung - T-cells, Pancreas - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Stomach - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 30: White matter - Myelination" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (1.01e-1)" "unprognostic (1.61e-2)" "unprognostic (1.12e-1)" "unprognostic (3.09e-2)" "unprognostic (4.76e-2)" "unprognostic (1.08e-1)" "unprognostic (1.96e-1)" "potential prognostic favorable (2.66e-4)" "unprognostic (2.30e-1)" "unprognostic (8.87e-2)" "unprognostic (2.98e-1)" "unprognostic (1.54e-3)" "unprognostic (2.84e-2)" "potential prognostic favorable (8.10e-4)" "unprognostic (1.29e-1)" "unprognostic (1.51e-1)" "unprognostic (1.30e-1)" "unprognostic (2.70e-3)" "unprognostic (2.13e-2)" "unprognostic (4.38e-2)" "unprognostic (1.24e-1)" "unprognostic (5.87e-2)" "unprognostic (2.23e-2)" "unprognostic (4.44e-2)" "unprognostic (2.70e-2)" "unprognostic (2.15e-2)" "unprognostic (5.05e-2)" "unprognostic (4.37e-2)" "unprognostic (5.65e-2)" CXorf38 MGC39350 ENSG00000185753 "Chromosome X open reading frame 38" Q8TB03 X 40626921-40647561 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050120 Approved Approved Vesicles,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 11 "Vesicles, Cytosol" "HPA050120: " "unprognostic (1.87e-3)" "unprognostic (1.94e-1)" "unprognostic (1.41e-1)" "unprognostic (2.25e-1)" "unprognostic (7.51e-2)" "unprognostic (2.05e-1)" "unprognostic (3.09e-1)" "unprognostic (6.97e-2)" "unprognostic (4.71e-2)" "unprognostic (1.07e-1)" "unprognostic (2.71e-2)" "unprognostic (1.39e-1)" "unprognostic (2.51e-1)" "potential prognostic unfavorable (2.66e-4)" "unprognostic (1.40e-2)" "unprognostic (5.68e-2)" "potential prognostic unfavorable (4.75e-4)" "unprognostic (1.68e-1)" "unprognostic (1.44e-1)" "unprognostic (3.39e-1)" "unprognostic (1.98e-2)" "potential prognostic unfavorable (1.18e-4)" "unprognostic (1.68e-1)" "unprognostic (8.93e-2)" "unprognostic (2.60e-1)" "unprognostic (1.26e-2)" "unprognostic (3.36e-2)" "unprognostic (7.82e-3)" "unprognostic (9.70e-2)" "unprognostic (9.74e-2)" "unprognostic (6.19e-2)" CXorf49 ENSG00000215115 "Chromosome X open reading frame 49" A8MYA2 X 71714371-71718285 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 59 "testis: 5.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 3.7;Sarcoma: 1.2" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 33: Sarcoma - Muscle contraction" "unprognostic (2.72e-2)" CXorf49B ENSG00000215113 "Chromosome X open reading frame 49B" A8MYA2 X 71763349-71767204 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 20 "testis: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 20: Myeloma - Immune response" "unprognostic (2.72e-2)" CXorf51A CXorf51 ENSG00000224440 "Chromosome X open reading frame 51A" A0A1B0GTR3 X 146814106-146814744 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 673 "testis: 67.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 66: Non-specific - Mitochondria" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" CXorf51B ENSG00000235699 "Chromosome X open reading frame 51B" P0DPH9 X 146809771-146810411 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 787 "testis: 78.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 1 CXorf58 FLJ25444 ENSG00000165182 "Chromosome X open reading frame 58" Q96LI9 X 23908006-23939509 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 8 "testis: 3.7" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 10.8;Early primary spermatocytes: 29.1;Early spermatids: 21.3;Hematopoietic stem cells: 9.7;Late primary spermatocytes: 42.4;Late spermatids: 9.1;Undifferentiated spermatogonia: 11.0" "Cell type enhanced" "Detected in many" "ependymal cell: 6.6;leukocyte: 8.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA031542, HPA031543, HPA031544" Uncertain Approved Nucleoplasm NA NA "Cluster 47: Testis - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 3: Early primary spermatocytes - Early meiosis" 2 Nucleoplasm "HPA031542: , HPA031543: , HPA031544: " CXorf65 ENSG00000204165 "Chromosome X open reading frame 65" A6NEN9 X 71103889-71106788 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 42 "testis: 25.4" "Cell type enriched" "Detected in single" 4 "Late spermatids: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA047396 Uncertain NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 1 "HPA047396: " "unprognostic (1.37e-3)" CXorf66 "RP11-35F15.2, SGPX" ENSG00000203933 "Chromosome X open reading frame 66" Q5JRM2 X 139955728-139965521 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 22 "testis: 12.7" "Group enriched" "Detected in some" 7 "Early spermatids: 135.4;Late primary spermatocytes: 95.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA048517 Approved "Perinuclear theca,Calyx,Mid piece,Principal piece,End piece,Annulus" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 9 "Perinuclear theca, Calyx, Annulus" "Mid piece, Principal piece, End piece" "HPA048517: " CXXC1 "CFP1, CGBP, hCGBP, HsT2645, PCCX1, PHF18, SPP1, ZCGPC1" ENSG00000154832 "CXXC finger protein 1" Q9P0U4 18 50282343-50287839 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044511 Supported Enhanced Nucleoplasm NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 29 Nucleoplasm "HPA044511: " "unprognostic (2.49e-1)" "unprognostic (6.99e-2)" "unprognostic (8.81e-2)" "unprognostic (5.55e-2)" "unprognostic (1.30e-1)" "unprognostic (1.16e-1)" "unprognostic (1.28e-1)" "unprognostic (1.82e-3)" "unprognostic (3.31e-2)" "potential prognostic unfavorable (1.12e-4)" "unprognostic (1.24e-3)" "potential prognostic favorable (2.95e-4)" "potential prognostic favorable (8.94e-5)" "potential prognostic unfavorable (8.04e-6)" "unprognostic (9.43e-2)" "unprognostic (4.24e-2)" "unprognostic (8.78e-2)" "unprognostic (7.19e-2)" "unprognostic (1.35e-3)" "unprognostic (1.53e-1)" "unprognostic (8.91e-3)" "unprognostic (5.02e-3)" "unprognostic (2.72e-2)" "potential prognostic unfavorable (2.29e-4)" "unprognostic (4.08e-1)" "unprognostic (1.25e-2)" "unprognostic (2.20e-1)" "unprognostic (5.15e-2)" "unprognostic (7.09e-2)" "unprognostic (2.24e-1)" "unprognostic (3.32e-2)" CXXC4 IDAX ENSG00000168772 "CXXC finger protein 4" 4 104468308-104494901 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 6.6;retina: 6.9" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 53.2;Corticotrophs: 90.2;Ependymal cells: 71.0;Gonadotrophs: 149.0;Lactotrophs: 102.9;Neuroendocrine cells: 73.8;Oligodendrocyte progenitor cells: 83.1;Other brain neurons: 70.7;Somatotrophs: 63.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 5.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 8.7" "Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Pituitary gland - Lactotropes, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036600, HPA036925" Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" Nucleoplasm "Golgi apparatus" "HPA036600: , HPA036925: " "unprognostic (4.77e-2)" "unprognostic (4.09e-2)" "unprognostic (1.85e-1)" "unprognostic (5.47e-2)" "unprognostic (1.20e-2)" "unprognostic (7.60e-3)" "potential prognostic favorable (6.90e-6)" "unprognostic (1.43e-3)" "unprognostic (4.43e-3)" "unprognostic (8.53e-2)" "potential prognostic favorable (2.09e-4)" "unprognostic (5.71e-2)" "unprognostic (5.86e-2)" "unprognostic (2.84e-2)" "unprognostic (1.04e-2)" "unprognostic (1.97e-1)" "unprognostic (2.96e-1)" CXXC5 "HSPC195, RINF, WID" ENSG00000171604 "CXXC finger protein 5" Q7LFL8 5 139647299-139683882 "Predicted intracellular proteins" Transcription "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 146.8" "Cell type enhanced" "Detected in many" "Early spermatids: 770.3;Esophageal apical cells: 296.2;Late primary spermatocytes: 311.8;Late spermatids: 250.5;Retinal horizontal cells: 288.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "MAIT T-cell: 30.1;memory B-cell: 85.4;naive B-cell: 97.1;NK-cell: 72.1;plasmacytoid DC: 59.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pituitary gland - Lactotropes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036508, HPA058148" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 27: Cerebellum - Synaptic function" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" Nucleoplasm Cytosol "HPA036508: , HPA058148: " "unprognostic (3.91e-3)" "unprognostic (9.01e-2)" "unprognostic (7.79e-3)" "unprognostic (1.60e-1)" "unprognostic (7.80e-3)" "unprognostic (1.79e-1)" "unprognostic (1.10e-1)" "unprognostic (2.26e-1)" "unprognostic (1.87e-1)" "unprognostic (1.39e-1)" "potential prognostic favorable (1.71e-4)" "unprognostic (3.40e-1)" "unprognostic (2.87e-2)" "unprognostic (7.18e-3)" "unprognostic (2.22e-1)" "unprognostic (8.93e-3)" "unprognostic (4.51e-2)" "unprognostic (1.80e-2)" "potential prognostic unfavorable (1.08e-5)" "unprognostic (1.23e-1)" "unprognostic (1.63e-2)" "unprognostic (8.27e-2)" "unprognostic (5.77e-2)" "unprognostic (4.50e-2)" "unprognostic (6.94e-2)" "unprognostic (1.33e-1)" "unprognostic (1.90e-1)" "unprognostic (2.35e-1)" "unprognostic (1.50e-1)" "unprognostic (2.06e-1)" "unprognostic (2.16e-1)" CYB561 "CYB561A1, FRRS2" ENSG00000008283 "Cytochrome b561" P49447 17 63432304-63446354 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Electron transport, Transport" Translocase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 287.2;Epididymal principal cells: 121.2;Esophageal apical cells: 175.7;Fallopian tube ciliated cells: 137.8;Prostatic glandular cells: 121.6;Respiratory ciliated cells: 152.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Adrenal gland - Adrenal medulla cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Skeletal muscle - Fibroblasts, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014753 Enhanced NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 1: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 49 "HPA014753: " "unprognostic (9.30e-3)" "potential prognostic unfavorable (1.97e-4)" "potential prognostic favorable (2.09e-4)" "unprognostic (3.16e-2)" "unprognostic (7.11e-2)" "unprognostic (5.37e-2)" "validated prognostic unfavorable (5.67e-5)" "validated prognostic unfavorable (2.79e-6)" "unprognostic (1.70e-1)" "unprognostic (8.06e-2)" "unprognostic (2.59e-1)" "unprognostic (2.31e-1)" "unprognostic (2.59e-1)" "unprognostic (2.18e-2)" "unprognostic (7.75e-3)" "unprognostic (4.64e-2)" "unprognostic (1.71e-1)" "unprognostic (1.24e-2)" "unprognostic (1.83e-2)" "unprognostic (1.62e-1)" "unprognostic (4.12e-2)" "unprognostic (3.77e-1)" "unprognostic (3.37e-1)" "unprognostic (4.39e-1)" "unprognostic (1.86e-1)" "unprognostic (1.49e-1)" "unprognostic (8.46e-2)" "unprognostic (2.65e-2)" "unprognostic (2.97e-1)" "unprognostic (5.42e-3)" "unprognostic (4.78e-3)" CYB561A3 CYBASC3 ENSG00000162144 "Cytochrome b561 family member A3" Q8NBI2 11 61348754-61362283 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Transport" "Oxidoreductase, Translocase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "adrenal gland: 292.2" "Group enriched" "Detected in many" 4 "Adrenal cortex cells: 165.8;Melanocytes: 530.3;pDCs: 295.1" "Cell type enhanced" "Detected in all" "ependymal cell: 44.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 8 "memory B-cell: 315.4;naive B-cell: 387.5;plasmacytoid DC: 843.5" "Group enriched" "Detected in all" 9 "B-cells: 387.5;dendritic cells: 843.5" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045674, HPA052548" Approved Approved Nucleoli,Vesicles NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 61: Schwann cells & Melanocytes - Mixed function" 21 Vesicles Nucleoli "HPA045674: , HPA052548: " "unprognostic (4.25e-1)" "unprognostic (1.58e-2)" "unprognostic (1.50e-3)" "unprognostic (7.74e-2)" "unprognostic (1.75e-2)" "unprognostic (6.35e-2)" "unprognostic (3.67e-1)" "unprognostic (6.16e-3)" "unprognostic (7.63e-2)" "potential prognostic favorable (7.67e-6)" "unprognostic (1.52e-1)" "unprognostic (1.46e-1)" "unprognostic (9.46e-3)" "unprognostic (1.90e-2)" "unprognostic (1.22e-1)" "unprognostic (2.25e-1)" "unprognostic (7.40e-2)" "unprognostic (2.14e-1)" "unprognostic (2.03e-1)" "unprognostic (2.80e-2)" "unprognostic (6.14e-2)" "unprognostic (3.58e-1)" "unprognostic (3.03e-1)" "unprognostic (1.66e-1)" "unprognostic (2.10e-1)" "unprognostic (1.59e-1)" "unprognostic (1.35e-1)" "unprognostic (1.21e-2)" "unprognostic (1.15e-1)" CYB561D1 "FLJ39035, FLJ44753" ENSG00000174151 "Cytochrome b561 family member D1" Q8N8Q1 1 109494052-109502932 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027028 Uncertain NA NA "Cluster 24: Non-specific - Transcription" "Cluster 49: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 3 "HPA027028: " "unprognostic (3.72e-2)" "unprognostic (1.41e-2)" "unprognostic (2.95e-2)" "unprognostic (2.50e-1)" "unprognostic (7.44e-2)" "unprognostic (4.24e-2)" "unprognostic (7.86e-2)" "unprognostic (1.92e-1)" "unprognostic (1.13e-3)" "unprognostic (4.08e-3)" "potential prognostic favorable (7.13e-7)" "unprognostic (2.27e-3)" "unprognostic (1.90e-2)" "potential prognostic unfavorable (3.66e-4)" "unprognostic (4.90e-2)" "unprognostic (1.50e-1)" "unprognostic (9.64e-3)" "unprognostic (1.65e-1)" "unprognostic (1.73e-2)" "unprognostic (2.01e-2)" "unprognostic (1.25e-1)" "potential prognostic favorable (2.85e-5)" "unprognostic (6.38e-2)" "unprognostic (1.06e-1)" "unprognostic (9.53e-3)" "unprognostic (2.33e-3)" "unprognostic (1.56e-1)" "unprognostic (1.46e-2)" "unprognostic (1.89e-1)" "unprognostic (5.25e-2)" "unprognostic (2.70e-1)" CYB561D2 "101F6, TSP10" ENSG00000114395 "Cytochrome b561 family member D2" O14569 3 50350845-50358460 "Enzymes, Predicted membrane proteins" "Electron transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Gastric chief cells: 1.1;Melanocytes: 2.0" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071862 Approved NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 55: Non-specific - Transcription" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 16 "HPA071862: " "unprognostic (1.10e-1)" "unprognostic (7.86e-2)" "unprognostic (2.77e-1)" "unprognostic (1.30e-1)" "unprognostic (1.88e-1)" "unprognostic (1.06e-1)" "unprognostic (1.31e-3)" "unprognostic (2.46e-2)" "unprognostic (1.42e-2)" "potential prognostic unfavorable (1.87e-4)" "unprognostic (3.45e-2)" "unprognostic (7.89e-3)" "unprognostic (4.34e-3)" "potential prognostic unfavorable (1.50e-4)" "unprognostic (1.28e-1)" "unprognostic (2.49e-1)" "unprognostic (7.23e-2)" "unprognostic (1.20e-1)" "unprognostic (5.91e-2)" "unprognostic (1.24e-1)" "unprognostic (3.23e-1)" "potential prognostic favorable (9.06e-4)" "unprognostic (2.21e-2)" "unprognostic (1.79e-1)" "unprognostic (3.44e-1)" "unprognostic (1.59e-1)" "unprognostic (2.30e-1)" "unprognostic (1.78e-1)" "unprognostic (1.33e-1)" "unprognostic (3.55e-1)" "unprognostic (3.48e-1)" CYB5A CYB5 ENSG00000166347 "Cytochrome b5 type A" P00167 18 74250846-74291973 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 828.0;liver: 2306.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 2211.1;Breast lactating cells: 1374.0;Enterocytes: 1661.0;Hepatocytes: 3986.6;Transitional alveolar cells: 1918.9;Urothelial cells: 1103.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Fibroblasts, Skin - Sebaceous gland cells, Testis - Leydig cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006333, HPA047548, HPA058547" Enhanced Enhanced Vesicles,Cytosol No No 1200000 "Cluster 34: B-cells - Unknown function" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 26 "Vesicles, Cytosol" "CAB006333: , HPA047548: , HPA058547: " "unprognostic (2.30e-2)" "unprognostic (3.74e-2)" "unprognostic (5.91e-2)" "unprognostic (8.83e-2)" "potential prognostic favorable (6.47e-4)" "unprognostic (4.84e-2)" "unprognostic (2.37e-1)" "potential prognostic favorable (6.91e-6)" "unprognostic (7.48e-2)" "unprognostic (9.63e-2)" "potential prognostic favorable (1.78e-7)" "unprognostic (2.37e-2)" "potential prognostic favorable (2.51e-4)" "validated prognostic favorable (3.82e-4)" "validated prognostic favorable (7.90e-4)" "unprognostic (5.67e-3)" "unprognostic (1.28e-1)" "unprognostic (9.60e-3)" "unprognostic (8.45e-2)" "unprognostic (1.56e-1)" "unprognostic (1.30e-1)" "unprognostic (3.66e-3)" "unprognostic (1.13e-2)" "unprognostic (2.32e-2)" "unprognostic (2.91e-2)" "unprognostic (3.01e-2)" "unprognostic (7.53e-2)" "unprognostic (1.80e-1)" "unprognostic (4.60e-1)" "unprognostic (1.90e-1)" "unprognostic (7.90e-3)" CYB5B CYB5-M ENSG00000103018 "Cytochrome b5 type B" O43169 16 69398402-69466264 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 190.3" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 692.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007893 Approved Approved "Endoplasmic reticulum,Centriolar satellite,Cytosol" NA NA 85000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 18: Adrenal cortex cells - Steroidogensis" 52 "Endoplasmic reticulum" "Centriolar satellite, Cytosol" "HPA007893: " "unprognostic (4.41e-1)" "unprognostic (7.07e-2)" "unprognostic (4.23e-2)" "unprognostic (3.48e-3)" "unprognostic (1.31e-1)" "unprognostic (6.19e-2)" "unprognostic (4.50e-1)" "unprognostic (7.71e-2)" "potential prognostic unfavorable (2.61e-4)" "unprognostic (3.29e-1)" "potential prognostic favorable (3.80e-6)" "unprognostic (9.90e-2)" "unprognostic (3.86e-2)" "potential prognostic unfavorable (7.11e-5)" "unprognostic (1.52e-2)" "unprognostic (2.86e-2)" "unprognostic (7.97e-3)" "unprognostic (1.87e-2)" "unprognostic (2.24e-1)" "unprognostic (3.18e-1)" "unprognostic (2.15e-1)" "unprognostic (6.22e-3)" "unprognostic (4.51e-2)" "unprognostic (1.68e-1)" "unprognostic (2.16e-2)" "unprognostic (2.68e-1)" "unprognostic (9.60e-2)" "unprognostic (1.14e-1)" "unprognostic (1.14e-2)" "unprognostic (1.56e-1)" "unprognostic (2.73e-1)" CYB5D1 FLJ32499 ENSG00000182224 "Cytochrome b5 domain containing 1" Q6P9G0 17 7857746-7862282 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 13.7;Early spermatids: 46.1;Ependymal cells: 25.2;Epicardial cells: 11.4;Late spermatids: 28.8" "Cell type enhanced" "Detected in many" "ependymal cell: 30.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021632 Uncertain Approved "Nucleoli,Golgi apparatus" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 42: Non-specific - Unknown function" "Cluster 34: Ciliated cells - Cilia assembly & function" "Nucleoli, Golgi apparatus" "HPA021632: " "unprognostic (1.51e-3)" "unprognostic (2.44e-1)" "unprognostic (2.24e-1)" "unprognostic (5.66e-2)" "unprognostic (1.62e-1)" "unprognostic (1.40e-1)" "unprognostic (1.48e-1)" "unprognostic (4.86e-3)" "unprognostic (4.42e-2)" "unprognostic (1.19e-2)" "validated prognostic favorable (1.24e-6)" "validated prognostic favorable (5.38e-4)" "unprognostic (4.71e-3)" "unprognostic (5.10e-2)" "unprognostic (3.05e-3)" "unprognostic (2.64e-1)" "unprognostic (5.97e-2)" "unprognostic (8.88e-2)" "unprognostic (2.75e-2)" "unprognostic (4.15e-2)" "unprognostic (2.39e-2)" "unprognostic (1.01e-2)" "unprognostic (8.49e-2)" "unprognostic (3.13e-1)" "unprognostic (7.23e-2)" "unprognostic (1.81e-1)" "unprognostic (2.62e-2)" "unprognostic (1.83e-1)" "unprognostic (2.73e-1)" "unprognostic (2.75e-2)" "unprognostic (1.56e-1)" CYB5D2 MGC32124 ENSG00000167740 "Cytochrome b5 domain containing 2" Q8WUJ1 17 4143168-4187310 "Predicted intracellular proteins, Predicted secreted proteins" Neurogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 226.2;Platelets: 149.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011032, HPA042299" Approved Approved "Endoplasmic reticulum,Plasma membrane" "Secreted to blood" Other NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 67: Testis - Mixed function" "Cluster 27: Non-specific - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 12 "Endoplasmic reticulum, Plasma membrane" "HPA011032: , HPA042299: " "unprognostic (2.63e-1)" "unprognostic (1.15e-1)" "unprognostic (2.92e-1)" "unprognostic (1.54e-2)" "unprognostic (1.53e-1)" "unprognostic (1.62e-1)" "unprognostic (5.06e-2)" "unprognostic (3.56e-1)" "unprognostic (4.62e-2)" "unprognostic (3.68e-2)" "validated prognostic favorable (3.52e-8)" "validated prognostic favorable (1.65e-5)" "potential prognostic favorable (7.78e-5)" "validated prognostic favorable (1.53e-5)" "validated prognostic favorable (5.33e-8)" "unprognostic (4.75e-2)" "unprognostic (6.81e-2)" "unprognostic (1.37e-1)" "unprognostic (1.59e-1)" "unprognostic (6.17e-2)" "unprognostic (1.59e-1)" "potential prognostic favorable (1.34e-4)" "unprognostic (1.84e-1)" "unprognostic (1.50e-1)" "unprognostic (9.01e-2)" "unprognostic (8.99e-2)" "unprognostic (4.66e-1)" "unprognostic (6.70e-2)" "unprognostic (1.71e-1)" "unprognostic (1.28e-1)" "unprognostic (1.31e-3)" CYB5R1 "humb5R2, NQO3A2" ENSG00000159348 "Cytochrome b5 reductase 1" Q9UHQ9 1 202961873-202967275 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 591.7" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 269.3;Migrating cytotrophoblasts: 348.3;Myonuclei: 194.0;Parietal cells: 249.3;Platelets: 304.7;Syncytiotrophoblasts: 388.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Breast - Breast glandular cells, Skin - Keratinocyte (other), Stomach - Parietal cells, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010531, HPA010641, HPA014147" Enhanced Approved Mitochondria,Cytosol NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." 15 Mitochondria Cytosol "HPA010531: , HPA010641: , HPA014147: " "unprognostic (1.57e-2)" "unprognostic (3.62e-2)" "unprognostic (1.73e-1)" "unprognostic (8.22e-3)" "unprognostic (6.31e-2)" "unprognostic (6.31e-3)" "unprognostic (1.22e-3)" "unprognostic (7.98e-3)" "unprognostic (7.81e-3)" "unprognostic (6.65e-2)" "potential prognostic favorable (4.83e-7)" "unprognostic (1.83e-2)" "unprognostic (3.24e-1)" "unprognostic (2.42e-2)" "unprognostic (1.15e-1)" "unprognostic (6.04e-3)" "unprognostic (1.13e-1)" "unprognostic (1.18e-2)" "unprognostic (6.68e-3)" "unprognostic (1.06e-1)" "unprognostic (1.11e-2)" "unprognostic (1.28e-1)" "unprognostic (5.91e-2)" "unprognostic (4.70e-2)" "potential prognostic unfavorable (2.35e-4)" "unprognostic (1.63e-1)" "unprognostic (2.44e-1)" "unprognostic (3.08e-1)" "unprognostic (1.41e-1)" "unprognostic (1.83e-2)" "unprognostic (1.14e-2)" CYB5R2 ENSG00000166394 "Cytochrome b5 reductase 2" Q6BCY4 11 7665100-7677222 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 129.1;testis: 127.0" "Cell type enhanced" "Detected in many" "Early spermatids: 248.3;Late primary spermatocytes: 297.7;Late spermatids: 1009.7;Rod photoreceptor cells: 70.8" "Cell type enhanced" "Detected in some" "committed oligodendrocyte precursor: 10.8;oligodendrocyte: 17.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "eosinophil: 6.1;memory B-cell: 10.6;naive B-cell: 2.8" "Group enriched" "Detected in many" 9 "B-cells: 10.6;granulocytes: 6.1" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Minor salivary glandular cells, Spleen - Fibroblasts_1, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in single" "HPA038962, HPA061707" Enhanced Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 47: Testis - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 55: Lymphoma - Immune response" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 6 "Golgi apparatus" Nucleoplasm "HPA038962: , HPA061707: " "unprognostic (5.50e-2)" "unprognostic (1.00e-1)" "unprognostic (2.50e-3)" "unprognostic (3.38e-1)" "potential prognostic unfavorable (9.53e-5)" "unprognostic (6.75e-2)" "unprognostic (3.65e-3)" "potential prognostic unfavorable (1.06e-4)" "unprognostic (1.09e-1)" "unprognostic (1.86e-1)" "unprognostic (3.45e-2)" "unprognostic (1.35e-2)" "unprognostic (1.16e-1)" "unprognostic (7.38e-3)" "unprognostic (3.10e-2)" "unprognostic (9.88e-2)" "unprognostic (7.19e-2)" "unprognostic (1.72e-2)" "unprognostic (6.09e-2)" "unprognostic (1.08e-2)" "unprognostic (2.44e-1)" "unprognostic (1.02e-2)" "unprognostic (5.07e-3)" "unprognostic (9.05e-2)" "unprognostic (4.78e-1)" "unprognostic (1.40e-1)" "unprognostic (6.57e-2)" "unprognostic (2.81e-2)" "unprognostic (2.66e-1)" "unprognostic (1.32e-1)" "unprognostic (1.69e-1)" CYB5R3 DIA1 ENSG00000100243 "Cytochrome b5 reductase 3" P00387 22 42615730-42720870 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 91.3;Endometrial secretory cells: 108.6;Epididymal basal cells: 79.4;Ocular epithelial cells: 99.3;Respiratory basal cells: 76.2;Respiratory secretory cells: 86.2" "Cell type enhanced" "Detected in all" "pericyte: 191.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Endothelial cells, Skin - Fibroblasts_2, Spleen - Fibroblasts_1, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001566 Approved Supported "Endoplasmic reticulum,Perinuclear theca,Calyx,Connecting piece,Mid piece,Principal piece" NA NA 2000000 "Cluster 25: Non-specific - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 100: Stratified epithelial cells - Barrier functions" 98 "Endoplasmic reticulum" "Perinuclear theca, Calyx, Connecting piece, Mid piece, Principal piece" "HPA001566: " "unprognostic (2.30e-2)" "unprognostic (5.84e-2)" "unprognostic (1.29e-1)" "unprognostic (4.74e-2)" "unprognostic (4.33e-1)" "unprognostic (9.04e-3)" "unprognostic (2.25e-1)" "unprognostic (1.31e-1)" "potential prognostic unfavorable (8.51e-4)" "unprognostic (2.07e-1)" "potential prognostic favorable (3.11e-4)" "unprognostic (5.83e-2)" "unprognostic (1.66e-2)" "potential prognostic unfavorable (2.90e-7)" "unprognostic (1.16e-1)" "unprognostic (2.20e-1)" "unprognostic (2.63e-1)" "unprognostic (1.30e-2)" "unprognostic (1.18e-1)" "unprognostic (2.41e-1)" "unprognostic (2.60e-2)" "unprognostic (1.57e-1)" "unprognostic (3.09e-1)" "unprognostic (5.09e-2)" "unprognostic (2.24e-2)" "unprognostic (4.79e-2)" "unprognostic (1.09e-1)" "unprognostic (1.59e-2)" "unprognostic (4.34e-2)" "unprognostic (9.07e-3)" "unprognostic (2.63e-1)" CYB5R4 "b5+b5R, dJ676J13.1, NCB5OR" ENSG00000065615 "Cytochrome b5 reductase 4" Q7L1T6 6 83859656-83967423 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 286.5;Late spermatids: 652.3;Neutrophil progenitors: 286.7;Neutrophils: 1022.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 200.2" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Neutrophils_2, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018992 Approved NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 39: Testis - Nuclear processes" "Cluster 48: Non-specific - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" "HPA018992: " "unprognostic (7.28e-2)" "unprognostic (2.37e-2)" "unprognostic (1.98e-2)" "potential prognostic unfavorable (6.57e-6)" "unprognostic (1.66e-2)" "potential prognostic favorable (9.92e-4)" "unprognostic (1.21e-2)" "unprognostic (3.78e-2)" "unprognostic (1.07e-2)" "unprognostic (1.40e-3)" "potential prognostic favorable (6.65e-7)" "unprognostic (8.64e-2)" "unprognostic (2.57e-1)" "unprognostic (1.19e-1)" "unprognostic (1.61e-1)" "unprognostic (4.20e-2)" "unprognostic (6.31e-2)" "unprognostic (1.51e-2)" "unprognostic (3.87e-1)" "unprognostic (1.33e-1)" "unprognostic (1.24e-2)" "unprognostic (3.39e-1)" "unprognostic (1.68e-1)" "unprognostic (1.96e-1)" "unprognostic (5.50e-3)" "unprognostic (2.21e-2)" "unprognostic (3.96e-1)" "unprognostic (1.82e-1)" "unprognostic (9.37e-2)" "unprognostic (1.92e-2)" "unprognostic (7.82e-2)" CYB5RL LOC606495 ENSG00000215883 "Cytochrome b5 reductase like" Q6IPT4 1 54169651-54200036 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 2.5;Epididymal principal cells: 2.6;Gastric chief cells: 4.4;Hofbauer cells: 3.4;Medullary thymic epithelial cells: 2.4;Paneth cells: 3.9;Tuft cells: 11.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042671, HPA060463" Approved Approved Nucleoplasm NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 24: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 95: Tuft cells - Chemosensory signaling" Nucleoplasm "HPA042671: , HPA060463: " "unprognostic (2.56e-2)" "unprognostic (7.18e-3)" "unprognostic (2.02e-1)" "unprognostic (6.39e-2)" "unprognostic (6.52e-2)" "unprognostic (2.57e-1)" "unprognostic (2.45e-1)" "unprognostic (3.48e-1)" "unprognostic (3.44e-3)" "unprognostic (1.55e-3)" "unprognostic (1.13e-3)" "unprognostic (8.77e-2)" "unprognostic (8.95e-2)" "potential prognostic unfavorable (8.88e-8)" "unprognostic (6.84e-3)" "unprognostic (1.19e-1)" "unprognostic (1.73e-1)" "unprognostic (2.08e-2)" "unprognostic (2.06e-1)" "unprognostic (1.65e-2)" "unprognostic (7.04e-2)" "unprognostic (1.09e-2)" "unprognostic (2.17e-2)" "unprognostic (6.17e-3)" "potential prognostic favorable (1.48e-4)" "unprognostic (6.82e-2)" "unprognostic (1.45e-2)" "unprognostic (1.56e-2)" "unprognostic (1.67e-1)" "unprognostic (1.42e-1)" "unprognostic (6.59e-2)" CYBA p22-PHOX ENSG00000051523 "Cytochrome b-245 alpha chain" P13498 16 88643275-88651083 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Electron transport, Transport" Oxidoreductase "Chronic granulomatous disease, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 777.5;lymphoid tissue: 781.6" "Cell type enhanced" "Detected in many" "cDC: 1107.9;Endometrial secretory cells: 1287.7;Gastric progenitor cells: 1281.7;Hofbauer cells: 2226.6;Kupffer cells: 1788.5;Macrophages: 1075.6;monocytes: 1478.9;Neutrophils: 1831.7;pDCs: 1603.0;Plasma cells: 2874.8" "Group enriched" "Detected in many" 5 "central nervous system macrophage: 293.7;leukocyte: 348.4;pericyte: 163.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 756.9" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Prostate - T-cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009492, HPA072667" Enhanced NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 35: RS4;11 - Unknown function" "Cluster 67: Plasma cells - Plasma cell differentiation" 30 "CAB009492: , HPA072667: " "unprognostic (3.14e-1)" "unprognostic (9.35e-3)" "unprognostic (2.61e-1)" "unprognostic (1.90e-2)" "unprognostic (1.36e-1)" "potential prognostic favorable (2.44e-5)" "unprognostic (8.08e-2)" "unprognostic (2.22e-1)" "unprognostic (6.18e-2)" "unprognostic (1.42e-1)" "potential prognostic unfavorable (3.38e-4)" "unprognostic (3.72e-3)" "potential prognostic favorable (1.78e-4)" "unprognostic (4.67e-2)" "unprognostic (1.42e-1)" "unprognostic (3.10e-2)" "unprognostic (1.26e-1)" "potential prognostic unfavorable (6.28e-4)" "unprognostic (3.36e-2)" "unprognostic (1.92e-1)" "unprognostic (1.21e-2)" "unprognostic (1.20e-3)" "unprognostic (1.79e-1)" "unprognostic (1.61e-1)" "unprognostic (1.26e-1)" "unprognostic (3.61e-1)" "unprognostic (3.20e-1)" "unprognostic (2.05e-1)" "unprognostic (6.70e-2)" "unprognostic (6.44e-2)" "unprognostic (2.39e-2)" CYBB "CGD, GP91-PHOX, NOX2" ENSG00000165168 "Cytochrome b-245 beta chain" P04839 X 37780018-37813461 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Electron transport, Ion transport, Transport" "Ion channel, Oxidoreductase, Voltage-gated channel" "Chronic granulomatous disease, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 150.2;lymphoid tissue: 141.4" "Cell type enhanced" "Detected in many" "Hofbauer cells: 269.9;Kupffer cells: 612.9;Macrophages: 418.0;Microglia: 358.1;Monocyte progenitors: 346.7;monocytes: 776.3;Neutrophil progenitors: 1957.9;Neutrophils: 352.3;pDCs: 233.4" "Cell type enriched" "Detected in many" 5 "central nervous system macrophage: 486.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 318.5" "Group enriched" "Detected in many" 5 "dendritic cells: 80.2;granulocytes: 106.4;monocytes: 318.5" "Group enriched" "Detected in some" 4 "Leukemia: 15.8;lymphoma: 29.8" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid gland - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA051227 Enhanced NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 5 "HPA051227: " "unprognostic (6.71e-3)" "unprognostic (8.30e-2)" "unprognostic (1.93e-1)" "unprognostic (8.94e-2)" "unprognostic (1.17e-1)" "unprognostic (2.43e-1)" "unprognostic (2.22e-1)" "unprognostic (1.41e-1)" "unprognostic (1.02e-1)" "unprognostic (1.70e-1)" "unprognostic (1.08e-2)" "unprognostic (3.95e-1)" "unprognostic (1.94e-1)" "unprognostic (1.59e-2)" "unprognostic (1.34e-1)" "unprognostic (2.92e-2)" "unprognostic (3.01e-2)" "unprognostic (8.52e-2)" "unprognostic (5.52e-2)" "unprognostic (1.05e-2)" "unprognostic (2.54e-1)" "unprognostic (1.51e-1)" "unprognostic (7.39e-2)" "unprognostic (5.77e-2)" "unprognostic (2.90e-2)" "unprognostic (1.07e-2)" "unprognostic (4.88e-2)" "unprognostic (2.16e-1)" "unprognostic (3.98e-2)" "unprognostic (1.71e-1)" "unprognostic (2.59e-1)" CYBC1 "C17orf62, Eros, FLJ90469, MGC4368" ENSG00000178927 "Cytochrome b-245 chaperone 1" Q9BQA9 17 82440912-82450829 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" Chaperone "Chronic granulomatous disease, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 107.7;Neutrophils: 125.0" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 77.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045696 Uncertain Uncertain "Plasma membrane,Cell Junctions" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 5: Spleen - Immune response" "Cluster 18: Non-specific - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 55 "Plasma membrane" "Cell Junctions" "HPA045696: " "unprognostic (9.42e-3)" "unprognostic (7.99e-2)" "unprognostic (1.74e-1)" "unprognostic (1.50e-1)" "unprognostic (1.87e-1)" "potential prognostic unfavorable (5.13e-4)" "unprognostic (3.57e-1)" "unprognostic (4.15e-2)" "potential prognostic unfavorable (1.60e-4)" "potential prognostic unfavorable (1.29e-4)" "unprognostic (1.66e-2)" "unprognostic (6.28e-2)" "potential prognostic unfavorable (1.01e-4)" "unprognostic (1.54e-2)" "unprognostic (7.82e-2)" "unprognostic (1.01e-1)" "unprognostic (9.82e-2)" "unprognostic (1.12e-1)" "unprognostic (1.41e-1)" "unprognostic (4.83e-1)" "unprognostic (1.18e-1)" "unprognostic (1.74e-1)" "unprognostic (1.92e-2)" "unprognostic (3.30e-2)" "unprognostic (2.98e-1)" "unprognostic (2.01e-1)" "unprognostic (5.15e-2)" "unprognostic (8.74e-2)" "unprognostic (1.60e-1)" CYBRD1 "CYB561A2, DCYTB, FLJ23462, FRRS3" ENSG00000071967 "Cytochrome b reductase 1" Q53TN4 2 171522247-171558129 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Electron transport, Transport" "Oxidoreductase, Translocase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 872.6;Fibroblasts: 336.6;Leydig cells: 252.2;Peritubular myoid cells: 264.1" "Cell type enhanced" "Detected in many" "fibroblast: 169.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 17.4;intermediate monocyte: 17.8;myeloid DC: 16.8;neutrophil: 9.8;non-classical monocyte: 13.7" "Group enriched" "Detected in many" 4 "dendritic cells: 16.8;granulocytes: 9.8;monocytes: 17.8" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Minor Salivary Gland - Macrophages, Pancreas - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014757 Approved Supported "Plasma membrane" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 75: Ovary - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 22 "Plasma membrane" "HPA014757: " "unprognostic (2.31e-2)" "unprognostic (2.72e-1)" "unprognostic (6.85e-2)" "unprognostic (1.64e-2)" "unprognostic (5.77e-2)" "unprognostic (2.22e-2)" "unprognostic (3.87e-2)" "potential prognostic unfavorable (1.98e-4)" "unprognostic (1.91e-2)" "unprognostic (6.46e-2)" "unprognostic (2.91e-2)" "unprognostic (1.09e-1)" "unprognostic (3.31e-3)" "unprognostic (2.13e-1)" "unprognostic (6.00e-3)" "unprognostic (4.43e-2)" "unprognostic (3.28e-2)" "unprognostic (1.19e-2)" "unprognostic (9.05e-2)" "unprognostic (1.14e-3)" "unprognostic (4.90e-3)" "unprognostic (1.25e-1)" "unprognostic (9.58e-2)" "unprognostic (3.72e-1)" "unprognostic (8.67e-2)" "unprognostic (4.14e-3)" "unprognostic (1.92e-2)" "unprognostic (2.46e-2)" "unprognostic (7.58e-2)" "unprognostic (2.74e-2)" "unprognostic (2.15e-1)" CYC1 UQCR4 ENSG00000179091 "Cytochrome c1" P08574 8 144095039-144097525 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" Translocase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 684.3;tongue: 676.8" "Cell type enhanced" "Detected in many" "Colonocytes: 554.8;Enteric stem cells: 468.6;Enteric transient amplifying cells: 632.2;Enterocytes: 490.4;Esophageal basal cells: 706.9;Esophageal suprabasal cells: 605.9;Parietal cells: 595.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001247 Supported Approved "Mitochondria,Equatorial segment" NA NA 76000 "Cluster 13: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cellular respiration" "Cluster 45: Non-specific - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 27 Mitochondria "Equatorial segment" "HPA001247: " "unprognostic (3.11e-1)" "potential prognostic unfavorable (1.83e-4)" "unprognostic (7.22e-2)" "unprognostic (2.17e-1)" "unprognostic (3.31e-1)" "unprognostic (9.99e-2)" "unprognostic (3.36e-1)" "unprognostic (8.43e-3)" "unprognostic (6.31e-2)" "unprognostic (2.47e-2)" "potential prognostic favorable (8.14e-4)" "unprognostic (2.58e-1)" "unprognostic (2.52e-2)" "unprognostic (2.80e-1)" "unprognostic (2.03e-3)" "unprognostic (1.73e-3)" "unprognostic (1.20e-1)" "unprognostic (1.28e-1)" "unprognostic (2.02e-1)" "unprognostic (2.08e-1)" "unprognostic (5.10e-2)" "unprognostic (2.05e-1)" "unprognostic (1.42e-1)" "unprognostic (1.21e-1)" "unprognostic (5.89e-2)" "unprognostic (3.38e-1)" "unprognostic (9.18e-2)" "unprognostic (2.84e-1)" "unprognostic (1.64e-1)" "unprognostic (2.20e-2)" "unprognostic (6.76e-2)" CYCS "CYC, HCS" ENSG00000172115 "Cytochrome c, somatic" P99999 7 25118656-25125260 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Electron transport, Respiratory chain, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 746.5" "Cell type enhanced" "Detected in all" "Colonocytes: 1028.9;Esophageal apical cells: 960.2;Esophageal suprabasal cells: 1228.9;Parietal cells: 2034.9;Vascular smooth muscle cells: 951.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Not detected" "Not detected" "CAB004222, CAB005126, CAB018597" Enhanced Supported Mitochondria NA NA 21000000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 23: Choroid plexus - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 103: Non-specific - Basic cellular processes" 30 Mitochondria "CAB004222: , CAB005126: , CAB018597: " "unprognostic (4.01e-2)" "unprognostic (6.16e-3)" "unprognostic (4.00e-2)" "unprognostic (1.77e-2)" "unprognostic (3.99e-2)" "unprognostic (2.13e-2)" "unprognostic (1.94e-2)" "potential prognostic unfavorable (8.39e-4)" "potential prognostic unfavorable (4.36e-5)" "potential prognostic unfavorable (3.37e-6)" "potential prognostic favorable (2.28e-4)" "unprognostic (9.11e-3)" "unprognostic (2.76e-1)" "unprognostic (2.10e-2)" "unprognostic (1.07e-3)" "potential prognostic unfavorable (4.15e-5)" "unprognostic (4.08e-2)" "unprognostic (4.30e-2)" "unprognostic (1.70e-1)" "unprognostic (1.48e-1)" "unprognostic (9.43e-2)" "unprognostic (8.41e-2)" "unprognostic (1.51e-1)" "unprognostic (4.80e-2)" "unprognostic (2.48e-2)" "unprognostic (3.21e-3)" "unprognostic (1.07e-2)" "unprognostic (1.91e-1)" "unprognostic (3.26e-1)" "potential prognostic unfavorable (4.86e-5)" "unprognostic (2.36e-1)" CYFIP1 "KIAA0068, P140SRA-1, SHYC" ENSG00000273749 "Cytoplasmic FMR1 interacting protein 1" Q7L576 15 22867052-22981063 "Predicted intracellular proteins" "Cell shape, Differentiation, Neurogenesis" "Actin-binding, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 12 "Microglia: 1105.8" "Cell type enriched" "Detected in all" 8 "central nervous system macrophage: 1301.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 23.5;intermediate monocyte: 25.0;myeloid DC: 22.1;non-classical monocyte: 12.6" "Group enriched" "Detected in many" 5 "dendritic cells: 22.1;monocytes: 25.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068106 Approved NA NA 780000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 58: Non-specific - Nuclear processes" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 36 "HPA068106: " "unprognostic (8.61e-2)" "unprognostic (3.98e-3)" "unprognostic (1.09e-1)" "unprognostic (8.42e-2)" "unprognostic (1.71e-1)" "unprognostic (3.87e-2)" "unprognostic (8.51e-2)" "unprognostic (1.31e-1)" "unprognostic (9.61e-2)" "potential prognostic favorable (3.68e-5)" "unprognostic (8.71e-2)" "unprognostic (2.89e-3)" "unprognostic (4.55e-2)" "unprognostic (8.42e-2)" "unprognostic (2.08e-3)" "potential prognostic unfavorable (9.91e-4)" "unprognostic (1.05e-1)" "unprognostic (1.07e-1)" "unprognostic (5.50e-2)" "unprognostic (2.40e-2)" "unprognostic (5.93e-2)" "unprognostic (1.06e-1)" "unprognostic (3.05e-1)" "unprognostic (1.69e-1)" "unprognostic (1.98e-1)" "unprognostic (3.00e-1)" "unprognostic (2.65e-2)" "unprognostic (2.76e-1)" CYFIP2 PIR121 ENSG00000055163 "Cytoplasmic FMR1 interacting protein 2" Q96F07 5 157266079-157395595 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Cell adhesion" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 82.2;kidney: 130.8" "Cell type enhanced" "Detected in many" "Corticotrophs: 260.5;Distal convoluted tubule cells: 404.4;Loop of henle epithelial cells: 519.8;Neutrophil progenitors: 422.9;Neutrophils: 606.9;Renal collecting duct principal cells: 363.8;Thymocytes: 272.7" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 78.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "lymphoma: 173.5" "Adipose subcutaneous - Smooth muscle cells, Breast - T-cells, Kidney - Ascending Loop of Henle cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Spleen - B-cells (Spleen), Stomach - Parietal cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB055519, HPA068106, HPA071459" Uncertain Approved "Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA 330000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 36: Brain & Liver - Signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 33 "Endoplasmic reticulum" "Plasma membrane, Cytosol" "CAB055519: , HPA068106: , HPA071459: " "unprognostic (2.85e-3)" "unprognostic (3.43e-2)" "unprognostic (1.28e-1)" "unprognostic (1.86e-1)" "unprognostic (1.08e-2)" "unprognostic (1.59e-2)" "unprognostic (2.07e-1)" "unprognostic (2.90e-2)" "unprognostic (1.72e-1)" "unprognostic (7.58e-2)" "potential prognostic favorable (2.81e-13)" "unprognostic (7.72e-3)" "unprognostic (1.85e-2)" "unprognostic (1.30e-1)" "unprognostic (7.76e-3)" "unprognostic (1.75e-3)" "unprognostic (3.44e-2)" "unprognostic (3.84e-2)" "unprognostic (2.68e-2)" "unprognostic (2.65e-1)" "unprognostic (1.07e-1)" "potential prognostic favorable (3.02e-4)" "unprognostic (4.11e-1)" "unprognostic (2.10e-1)" "unprognostic (1.07e-3)" "unprognostic (1.37e-2)" "unprognostic (3.04e-2)" "unprognostic (1.54e-1)" "unprognostic (9.57e-2)" "unprognostic (8.00e-2)" "unprognostic (4.60e-2)" CYGB "HGB, STAP" ENSG00000161544 Cytoglobin Q8WWM9 17 76527356-76551175 "Predicted intracellular proteins, Transporters" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 112.2" "Cell type enhanced" "Detected in many" "Ependymal cells: 32.6;Fibroblasts: 75.8;Innate lymphoid cells: 32.4;Leydig cells: 102.3;Melanocytes: 133.4;Pericytes: 94.8;Peritubular myoid cells: 27.6;Respiratory ciliated cells: 51.1;Retinal bipolar cells: 31.9;Thymocytes: 44.9;Vascular endothelial cells: 27.4" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 45.1;ependymal cell: 44.1" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 91.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 2.2" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 8 "Neuroblastoma: 103.1;skin cancer: 110.9" "Breast - Endothelial cells, Kidney - Fibroblasts, Pituitary gland - Fibroblasts, Prostate - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017757, HPA061642" Approved Approved Supported "Nuclear speckles,Cytosol" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 110: Mural cells - ECM organization" 5 "Nuclear speckles" Cytosol "HPA017757: , HPA061642: " "unprognostic (4.58e-2)" "unprognostic (5.39e-2)" "unprognostic (2.40e-2)" "unprognostic (5.73e-2)" "unprognostic (6.75e-2)" "unprognostic (6.06e-3)" "potential prognostic unfavorable (3.10e-4)" "unprognostic (3.01e-2)" "unprognostic (1.62e-1)" "unprognostic (1.93e-1)" "unprognostic (5.63e-2)" "unprognostic (1.66e-3)" "unprognostic (1.20e-2)" "unprognostic (1.93e-3)" "unprognostic (1.19e-1)" "unprognostic (2.01e-1)" "unprognostic (9.28e-2)" "unprognostic (9.14e-2)" "unprognostic (7.42e-2)" "unprognostic (1.20e-1)" "unprognostic (5.45e-2)" "unprognostic (7.96e-2)" "unprognostic (6.67e-2)" "unprognostic (1.97e-2)" "unprognostic (4.29e-1)" "unprognostic (5.05e-2)" "unprognostic (4.19e-2)" "unprognostic (1.96e-2)" "unprognostic (4.30e-2)" "unprognostic (2.07e-2)" "unprognostic (9.34e-3)" CYLC1 ENSG00000183035 "Cylicin 1" P35663 X 83861126-83886699 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 297 "testis: 29.7" "Group enriched" "Detected in some" 6 "Early spermatids: 545.1;Late spermatids: 2138.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA070355, HPA078303" Enhanced Supported "Perinuclear theca,Calyx" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" Calyx "Perinuclear theca" "HPA070355: , HPA078303: " CYLC2 ENSG00000155833 "Cylicin 2" Q14093 9 102995311-103018488 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 437 "testis: 43.6" "Cell type enhanced" "Detected in some" "Early spermatids: 2413.7;Late primary spermatocytes: 908.7;Late spermatids: 3728.0" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA062456 Supported "Perinuclear theca,Calyx" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 6: Non-specific - Immune response" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" Calyx "Perinuclear theca" "HPA062456: " CYLD "CYLD1, KIAA0849, USPL2" ENSG00000083799 "CYLD lysine 63 deubiquitinase" Q9NQC7 16 50742050-50801935 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Immunity, Innate immunity, Ubl conjugation pathway, Wnt signaling pathway" "Hydrolase, Protease, Thiol protease" "Amyotrophic lateral sclerosis, Cancer-related genes, Disease variant, Neurodegeneration, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 89.0" "Cell type enhanced" "Detected in many" "Neutrophils: 361.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011713, HPA050095, HPA077163" Approved Supported "Nucleoplasm,Primary cilium transition zone,Centriolar satellite,Basal body,Principal piece" Yes No "Cluster 42: Non-specific - Vesicular transport" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 82: Dendritic cells - Antigen presentation" 141 "Centriolar satellite" "Nucleoplasm, Primary cilium transition zone, Basal body, Principal piece" "CAB011713: , HPA050095: , HPA077163: " "unprognostic (4.08e-2)" "unprognostic (2.28e-1)" "unprognostic (5.67e-3)" "unprognostic (1.24e-1)" "unprognostic (6.54e-2)" "unprognostic (6.35e-2)" "unprognostic (1.77e-1)" "unprognostic (2.53e-1)" "unprognostic (1.18e-1)" "unprognostic (5.58e-2)" "potential prognostic favorable (4.60e-4)" "unprognostic (6.53e-2)" "unprognostic (2.06e-1)" "unprognostic (7.95e-2)" "unprognostic (4.17e-3)" "unprognostic (1.87e-2)" "unprognostic (1.33e-1)" "unprognostic (6.64e-2)" "unprognostic (3.59e-1)" "unprognostic (7.34e-2)" "unprognostic (5.01e-3)" "unprognostic (1.55e-1)" "unprognostic (1.39e-2)" "unprognostic (2.06e-1)" "unprognostic (1.84e-2)" "unprognostic (1.25e-1)" "unprognostic (1.71e-1)" "unprognostic (8.86e-2)" "unprognostic (1.74e-1)" "unprognostic (7.56e-3)" "unprognostic (3.10e-1)" CYP11A1 "CYP11A, P450SCC" ENSG00000140459 "Cytochrome P450 family 11 subfamily A member 1" P05108 15 74337759-74367646 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Steroidogenesis, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 25 "adrenal gland: 990.8" "Cell type enhanced" "Detected in some" "Adrenal cortex cells: 104.0;Choroid plexus epithelial cells: 25.2;Cytotrophoblasts: 25.1;Extravillous trophoblasts: 88.9;Migrating cytotrophoblasts: 43.9;Peritubular myoid cells: 67.3;Syncytiotrophoblasts: 371.8" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 13.8;ependymal cell: 26.0;fibroblast: 18.9" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 11.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 48 "basophil: 10.3" "Lineage enriched" "Detected in single" 48 "granulocytes: 10.3" "Cancer enhanced" "Detected in some" "testis cancer: 7.6" "Adrenal gland - Adrenal cortex cells, Prostate - Fibroblasts, Testis - Leydig cells" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basal ganglia: 2.4;hippocampal formation: 1.5;hypothalamus: 1.7;midbrain: 5.9;pons: 1.5" HPA016436 Enhanced NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." 1 "HPA016436: " "unprognostic (1.53e-1)" "unprognostic (2.39e-2)" "unprognostic (2.77e-1)" "potential prognostic unfavorable (3.14e-5)" "unprognostic (5.01e-2)" "unprognostic (4.22e-1)" "unprognostic (8.64e-3)" "unprognostic (6.94e-3)" "unprognostic (9.52e-2)" "unprognostic (9.13e-3)" "unprognostic (2.10e-1)" "unprognostic (9.57e-2)" "unprognostic (2.28e-1)" "unprognostic (9.45e-2)" CYP11B1 "CPN1, CYP11B, FHI, P450C11" ENSG00000160882 "Cytochrome P450 family 11 subfamily B member 1" P15538 8 142872356-142879846 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroidogenesis" "Monooxygenase, Oxidoreductase" "Congenital adrenal hyperplasia, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 842 "adrenal gland: 3344.5" "Cell type enriched" "Detected in some" 16 "Adrenal cortex cells: 2302.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adrenal gland - Adrenal cortex cells, Testis - Late spermatids" "HPA049171, HPA049565, HPA056348, HPA057752" Supported Approved Mitochondria NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 17: Choroid plexus - Cilium" "Cluster 18: Adrenal cortex cells - Steroidogensis" Mitochondria "HPA049171: , HPA049565: , HPA056348: , HPA057752: " CYP11B2 "ALDOS, CPN2, CYP11B, CYP11BL, P-450C18, P450aldo" ENSG00000179142 "Cytochrome P450 family 11 subfamily B member 2" P19099 8 142910559-142917843 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism, Steroidogenesis" "Monooxygenase, Oxidoreductase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1269 "adrenal gland: 178.8" "Cell type enriched" "Detected in some" 14 "Adrenal cortex cells: 32.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049171, HPA049565, HPA056348, HPA057752" Supported Approved Mitochondria NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 18: Adrenal cortex cells - Steroidogensis" Mitochondria "HPA049171: , HPA049565: , HPA056348: , HPA057752: " CYP17A1 "CPT7, CYP17, P450C17, S17AH" ENSG00000148795 "Cytochrome P450 family 17 subfamily A member 1" P05093 10 102830531-102837472 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism, Steroidogenesis" "Lyase, Monooxygenase, Oxidoreductase" "Congenital adrenal hyperplasia, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 91 "adrenal gland: 8353.3" "Cell type enriched" "Detected in some" 48 "Adrenal cortex cells: 3116.7" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 49.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adrenal gland - Adrenal cortex cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA048533 Enhanced Approved Vesicles "Intracellular and membrane" Enzyme NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 70: DU4475 - Unknown function" "Cluster 18: Adrenal cortex cells - Steroidogensis" Vesicles "HPA048533: " "unprognostic (1.87e-1)" "potential prognostic favorable (5.84e-5)" "unprognostic (1.21e-2)" "unprognostic (1.56e-1)" "unprognostic (2.14e-3)" "unprognostic (3.68e-3)" "unprognostic (2.96e-2)" "unprognostic (2.92e-1)" "unprognostic (3.81e-2)" "unprognostic (2.02e-1)" "unprognostic (5.04e-3)" "unprognostic (3.24e-1)" CYP19A1 "ARO, ARO1, aromatase, CPV1, CYAR, CYP19, P-450AROM" ENSG00000137869 "Cytochrome P450 family 19 subfamily A member 1" P11511 15 51208057-51338601 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes, Disease variant, FDA approved drug targets, Pseudohermaphroditism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "placenta: 117.1" "Cell type enriched" "Detected in many" 45 "Syncytiotrophoblasts: 5387.9" "Cell type enhanced" "Detected in some" "medium spiny neuron: 4.6;thalamic excitatory: 10.8" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 2.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "lymphoma: 5.3;testis cancer: 15.0" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB000355, HPA051194" Enhanced Uncertain Mitochondria NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 17 Mitochondria "CAB000355: , HPA051194: " "unprognostic (2.17e-2)" "unprognostic (1.79e-2)" "unprognostic (2.29e-1)" "unprognostic (9.85e-2)" "unprognostic (1.23e-1)" "unprognostic (3.29e-1)" "potential prognostic unfavorable (2.91e-6)" "unprognostic (2.22e-2)" "unprognostic (3.30e-1)" "unprognostic (5.17e-2)" "unprognostic (2.42e-1)" CYP1A1 "CP11, CYP1, P1-450, P450-C, P450DX" ENSG00000140465 "Cytochrome P450 family 1 subfamily A member 1" P04798 15 74719542-74725536 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" "Lyase, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 61.8;urinary bladder: 59.6" "Cell type enhanced" "Detected in some" "Endometrial glandular cells: 10.3;Endometrial secretory cells: 8.8;Epididymal clear cells: 51.0;Gastric progenitor cells: 6.4;Hepatocytes: 13.6;Salivary duct cells: 5.2;Urothelial cells: 41.7;Vascular endothelial cells: 13.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "Bladder Urothelial Carcinoma (TCGA): 118.6;Liver Hepatocellular Carcinoma (TCGA): 31.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder cancer: 53.3;Esophageal cancer: 95.1" "Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" CAB018654 Uncertain NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 1 "CAB018654: " "unprognostic (9.20e-2)" "unprognostic (5.35e-2)" "unprognostic (3.30e-1)" "unprognostic (2.07e-1)" "unprognostic (4.73e-2)" "unprognostic (1.14e-2)" "unprognostic (1.23e-1)" "unprognostic (5.18e-2)" CYP1A2 "CP12, P3-450" ENSG00000140505 "Cytochrome P450 family 1 subfamily A member 2" P05177 15 74748845-74756607 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Lyase, Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 236 "liver: 478.4" "Cell type enriched" "Detected in some" 7 "Hepatocytes: 756.3" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bladder Urothelial Carcinoma (TCGA): 16.9;Liver Hepatocellular Carcinoma (TCGA): 33.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.1" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.1" "Low cancer specificity" "Detected in single" "Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" CAB016531 Enhanced NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 93: Hepatocytes - Bile production & excretion" 2 "CAB016531: " "unprognostic (2.27e-3)" "unprognostic (1.24e-1)" "unprognostic (2.21e-2)" "unprognostic (5.30e-2)" "unprognostic (1.50e-1)" "potential prognostic favorable (9.27e-5)" "unprognostic (5.55e-3)" "unprognostic (3.85e-2)" "unprognostic (1.22e-1)" "unprognostic (5.71e-2)" CYP1B1 "CP1B, GLC3A" ENSG00000138061 "Cytochrome P450 family 1 subfamily B member 1" Q16678 2 38066973-38109902 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism, Steroid metabolism" "Lyase, Monooxygenase, Oxidoreductase" "Disease variant, Glaucoma, Peters anomaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 160.5;Endometrial secretory cells: 239.2;Fallopian secretory cells: 130.1;Fibroblasts: 273.1;Kupffer cells: 145.5;Leydig cells: 170.6;Medullary thymic epithelial cells: 148.8;monocytes: 186.0;Neutrophils: 373.6;Peritubular myoid cells: 183.6;Pituicytes/FSCs: 256.8;Salivary duct cells: 203.5;Smooth muscle cells: 153.4;Urothelial cells: 157.4;Vascular endothelial cells: 167.2" "Cell type enriched" "Detected in many" 8 "fibroblast: 507.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "classical monocyte: 157.2" "Lineage enriched" "Detected in many" 24 "monocytes: 157.2" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Kidney - Fibroblasts" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 4 "midbrain: 16.4;spinal cord: 51.7" "CAB011705, HPA026863" Approved Uncertain Mitochondria NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 75: Ovary - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" Mitochondria "CAB011705: , HPA026863: " "unprognostic (8.23e-2)" "unprognostic (1.62e-2)" "unprognostic (6.86e-2)" "unprognostic (1.57e-1)" "unprognostic (3.95e-2)" "unprognostic (6.77e-2)" "unprognostic (5.02e-3)" "potential prognostic unfavorable (6.68e-4)" "unprognostic (1.29e-1)" "unprognostic (8.57e-3)" "unprognostic (8.29e-3)" "unprognostic (2.14e-3)" "unprognostic (4.84e-2)" "unprognostic (8.48e-2)" "unprognostic (5.02e-2)" "unprognostic (3.58e-2)" "unprognostic (1.28e-2)" "unprognostic (3.65e-3)" "unprognostic (1.88e-2)" "unprognostic (2.65e-1)" "unprognostic (2.57e-3)" "unprognostic (4.28e-1)" "unprognostic (2.53e-1)" "unprognostic (3.44e-1)" "unprognostic (1.09e-2)" "unprognostic (4.80e-2)" "unprognostic (1.17e-1)" "potential prognostic unfavorable (1.61e-4)" "unprognostic (1.87e-1)" "unprognostic (3.24e-2)" "unprognostic (7.23e-2)" CYP20A1 CYP-M ENSG00000119004 "Cytochrome P450 family 20 subfamily A member 1" Q6UW02 2 203238977-203306026 "Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055872, HPA058461" Uncertain Uncertain "Nucleoplasm,Plasma membrane,Cell Junctions,Actin filaments" No No "Cluster 16: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 63: Non-specific - Protein processing" "Cluster 94: Gonadal somatic cells - Mixed function" 3 "Plasma membrane, Cell Junctions, Actin filaments" Nucleoplasm "HPA055872: , HPA058461: " "unprognostic (6.53e-2)" "unprognostic (2.70e-2)" "unprognostic (4.65e-2)" "unprognostic (3.24e-2)" "unprognostic (2.61e-1)" "unprognostic (2.86e-1)" "unprognostic (1.44e-1)" "unprognostic (1.27e-2)" "unprognostic (1.35e-2)" "unprognostic (7.31e-2)" "unprognostic (2.01e-3)" "potential prognostic favorable (1.49e-4)" "unprognostic (1.97e-2)" "unprognostic (5.67e-2)" "unprognostic (1.26e-1)" "unprognostic (1.44e-2)" "unprognostic (8.16e-2)" "unprognostic (3.10e-2)" "unprognostic (2.37e-2)" "unprognostic (1.94e-1)" "unprognostic (1.31e-1)" "unprognostic (3.82e-1)" "unprognostic (3.49e-2)" "unprognostic (2.01e-1)" "unprognostic (2.62e-2)" "unprognostic (2.50e-1)" "unprognostic (8.18e-3)" "unprognostic (2.56e-1)" "unprognostic (5.03e-1)" "unprognostic (2.59e-3)" "unprognostic (5.58e-3)" CYP21A2 "CA21H, CAH1, CPS1, CYP21, CYP21B, P450c21B" ENSG00000231852 "Cytochrome P450 family 21 subfamily A member 2" P08686 6 32038327-32041644 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Steroidogenesis" "Monooxygenase, Oxidoreductase" "Congenital adrenal hyperplasia, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 44 "adrenal gland: 2046.8" "Cell type enhanced" "Detected in some" "Adrenal cortex cells: 1.8;Astrocytes: 1.3;Proximal tubule cells: 6.4" "Cell type enhanced" "Detected in single" "astrocyte: 2.3" "Cancer enhanced" "Detected in single" "Liver Hepatocellular Carcinoma (TCGA): 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA048979, HPA053371" Enhanced NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 15: Kidney cancer - Membrane components" "Cluster 88: Proximal tubular cells - Transmembrane transport" 1 "HPA048979: , HPA053371: " "unprognostic (2.55e-1)" "potential prognostic favorable (7.59e-4)" "unprognostic (8.81e-2)" "potential prognostic favorable (1.25e-5)" "potential prognostic favorable (4.93e-4)" CYP24A1 "CP24, CYP24, lncBCAS1-4_1, P450-CC24" ENSG00000019186 "Cytochrome P450 family 24 subfamily A member 1" Q07973 20 54153446-54173986 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" "Monooxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "endometrium 1: 14.1;kidney: 31.6;lymphoid tissue: 9.9;placenta: 9.4;urinary bladder: 27.0" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 48.3;Basal prostatic cells: 17.4;Endometrial secretory cells: 88.5;Epididymal basal cells: 52.4;Loop of henle epithelial cells: 42.9;Ocular epithelial cells: 20.5;Papillary tip epithelial cells: 87.7;Proximal tubule cells: 23.3;Respiratory basal cells: 65.4;Suprabasal keratinocytes: 17.5;Urothelial cells: 35.1" "Cell type enriched" "Detected in some" 4 "endothelial cell: 8.0" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 32.8;Lung Adenocarcinoma (TCGA): 40.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells (progenitors), Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Prostate - Urothelial cells, Skin - Inner root sheath cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA022261 Enhanced Approved Mitochondria NA Yes "Cluster 11: T-cells - Unknown function" "Cluster 72: Kidney - Transmembrane transport" "Cluster 1: Neurons - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 35 Mitochondria "HPA022261: " "unprognostic (1.60e-1)" "potential prognostic favorable (1.91e-8)" "unprognostic (1.11e-2)" "unprognostic (8.90e-2)" "unprognostic (1.43e-3)" "unprognostic (1.33e-2)" "unprognostic (1.83e-2)" "unprognostic (2.60e-2)" "unprognostic (1.65e-1)" "potential prognostic unfavorable (6.13e-4)" "unprognostic (1.75e-2)" "unprognostic (3.03e-1)" "unprognostic (1.09e-1)" "unprognostic (5.95e-2)" "unprognostic (5.03e-3)" "potential prognostic unfavorable (1.02e-4)" "unprognostic (7.74e-3)" "unprognostic (2.47e-2)" "unprognostic (2.24e-2)" "unprognostic (7.22e-3)" CYP26A1 "CP26, CYP26, P450RAI, P450RAI1" ENSG00000095596 "Cytochrome P450 family 26 subfamily A member 1" O43174 10 93073475-93077885 "Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 27 "liver: 16.8" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 10.6;Breast myoepithelial cells: 10.3;Conjunctival goblet cells: 11.7;Endometrial glandular cells: 26.2;Endometrial luminal cells: 30.7;Müller glia: 27.2;Ocular epithelial cells: 11.6;Respiratory basal cells: 8.1;Respiratory ionocytes: 53.3;Respiratory secretory cells: 7.7;Salivary duct cells: 6.9" "Group enriched" "Detected in some" 9 "central nervous system macrophage: 5.6;deep-layer corticothalamic and 6b: 12.0;deep-layer near-projecting: 11.4;MGE interneuron: 8.0" "Cancer enhanced" "Detected in some" "Lung Squamous Cell Carcinoma (TCGA): 3.7;Testicular Germ Cell Tumor (TCGA): 3.7" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 10.7" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebral cortex: 9.1" NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 14: Neurons - Synaptic function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" "unprognostic (5.94e-2)" "unprognostic (3.76e-2)" "unprognostic (4.14e-1)" "unprognostic (3.93e-2)" "unprognostic (1.16e-2)" "unprognostic (3.68e-2)" "unprognostic (1.68e-1)" CYP26B1 P450RAI-2 ENSG00000003137 "Cytochrome P450 family 26 subfamily B member 1" Q9NR63 2 72129238-72147862 "Disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Monooxygenase, Oxidoreductase" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 34.6;skin 1: 29.6" "Group enriched" "Detected in many" 5 "Leydig cells: 110.6;Peritubular myoid cells: 235.8" "Group enriched" "Detected in many" 5 "deep-layer near-projecting: 39.4;lower rhombic lip: 62.9;upper rhombic lip: 22.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "pons: 111.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 38.6" "Breast - Adipocytes (Breast), Liver - Vascular endothelial cells, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA012567 Uncertain Approved Cytosol No No "Cluster 2: Non-specific - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 94: Gonadal somatic cells - Mixed function" 14 Cytosol "HPA012567: " "unprognostic (9.77e-2)" "unprognostic (1.93e-1)" "unprognostic (1.56e-1)" "unprognostic (1.16e-1)" "unprognostic (2.05e-1)" "unprognostic (1.37e-1)" "unprognostic (3.05e-2)" "unprognostic (5.50e-2)" "unprognostic (2.32e-1)" "unprognostic (4.21e-2)" "unprognostic (1.88e-2)" "potential prognostic favorable (9.73e-5)" "unprognostic (2.49e-1)" "potential prognostic unfavorable (4.86e-6)" "unprognostic (1.90e-1)" "unprognostic (1.03e-1)" "unprognostic (2.31e-1)" "unprognostic (1.35e-1)" "unprognostic (1.68e-1)" "unprognostic (8.04e-2)" "unprognostic (2.23e-2)" "unprognostic (1.55e-2)" "unprognostic (3.87e-2)" "unprognostic (2.76e-1)" "unprognostic (2.61e-1)" "unprognostic (3.41e-1)" "unprognostic (2.69e-3)" "unprognostic (1.54e-1)" CYP26C1 ENSG00000187553 "Cytochrome P450 family 26 subfamily C member 1" Q6V0L0 10 93060798-93069540 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Lipid metabolism" "Monooxygenase, Oxidoreductase" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Epicardial cells: 2.3;Epididymal clear cells: 4.1;Innate lymphoid cells: 4.7;Microglia: 12.7" "Cell type enriched" "Detected in some" 7 "central nervous system macrophage: 14.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adrenal gland - Adrenal medulla cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 15: Kidney cancer - Membrane components" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" CYP27A1 "CP27, CTX, CYP27" ENSG00000135929 "Cytochrome P450 family 27 subfamily A member 1" Q02318 2 218781749-218815293 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "choroid plexus: 193.4;liver: 575.4" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 185.3;Enterocytes: 225.7;Hepatocytes: 513.1;Oligodendrocytes: 143.8;Retinal pigment epithelial cells: 298.4" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 168.2;oligodendrocyte: 201.3" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 337.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "classical monocyte: 151.6;neutrophil: 126.9" "Group enriched" "Detected in many" 21 "granulocytes: 126.9;monocytes: 151.6" "Cancer enhanced" "Detected in many" "liver cancer: 29.9;skin cancer: 65.6" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Fibroblasts, Liver - Hepatocytes, Lung - Macrophages, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059155 Enhanced Approved Mitochondria,Cytosol NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 30: White matter - Myelination" "Cluster 18: Liver cancer - Metabolism" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" Mitochondria Cytosol "HPA059155: " "unprognostic (2.54e-1)" "potential prognostic favorable (3.65e-4)" "unprognostic (3.02e-2)" "unprognostic (2.21e-2)" "unprognostic (2.90e-1)" "unprognostic (1.36e-2)" "validated prognostic unfavorable (5.59e-4)" "validated prognostic unfavorable (2.23e-7)" "unprognostic (1.83e-2)" "unprognostic (5.43e-3)" "potential prognostic favorable (2.52e-7)" "unprognostic (2.41e-3)" "potential prognostic favorable (7.15e-6)" "validated prognostic favorable (3.28e-5)" "validated prognostic favorable (1.33e-5)" "unprognostic (1.75e-3)" "unprognostic (7.71e-2)" "unprognostic (5.24e-3)" "unprognostic (2.92e-1)" "unprognostic (2.02e-1)" "unprognostic (2.96e-3)" "unprognostic (2.43e-2)" "unprognostic (2.96e-1)" "unprognostic (3.03e-3)" "unprognostic (2.69e-1)" "unprognostic (3.71e-2)" "unprognostic (9.55e-2)" "unprognostic (1.64e-2)" "unprognostic (1.91e-1)" "unprognostic (1.05e-1)" "unprognostic (2.28e-1)" CYP27B1 "CYP1, P450c1, PDDR, VDD1" ENSG00000111012 "Cytochrome P450 family 27 subfamily B member 1" O15528 12 57762334-57768986 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" "Monooxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 18.6;thyroid gland: 5.3" "Cell type enhanced" "Detected in some" "Adrenal cortex cells: 4.3;Basal keratinocytes: 4.1;Breast hormone-responsive cells: 4.4;Breast lactating cells: 17.4;Breast secretory cells: 4.0;Cholangiocytes: 3.9;Epicardial cells: 4.5;Epididymal efferent duct absorptive cells: 6.4;Esophageal basal cells: 4.8;Pancreatic acinar cells: 5.0;Proximal tubule cells: 7.2;Retinal ganglion cells: 3.9" "Low cell type specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 6 "MAIT T-cell: 1.2" "Lineage enriched" "Detected in single" 12 "T-cells: 1.2" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 7: Liver cancer - Metabolism" "Cluster 4: Breast lactating luminal cells - Lactation" "unprognostic (6.06e-3)" "unprognostic (1.58e-1)" "unprognostic (1.50e-2)" "potential prognostic unfavorable (2.54e-5)" "unprognostic (1.79e-1)" "unprognostic (2.53e-1)" "unprognostic (1.02e-2)" "unprognostic (9.18e-3)" "unprognostic (2.76e-2)" "unprognostic (3.03e-3)" "unprognostic (2.17e-1)" "unprognostic (2.11e-1)" "unprognostic (2.69e-1)" "unprognostic (1.06e-2)" "unprognostic (1.08e-1)" "unprognostic (7.95e-2)" "unprognostic (2.94e-2)" "unprognostic (2.05e-1)" "unprognostic (2.46e-1)" "unprognostic (1.88e-1)" "unprognostic (4.01e-2)" "unprognostic (3.98e-2)" "potential prognostic unfavorable (7.81e-4)" "unprognostic (4.83e-1)" CYP27C1 FLJ16008 ENSG00000186684 "Cytochrome P450 family 27 subfamily C member 1" Q4G0S4 2 127183832-127220313 "Enzymes, Predicted intracellular proteins" "Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skin 1: 4.8" "Cell type enhanced" "Detected in some" "Breast lactating cells: 34.1;Decidual stromal cells: 13.2;Endometrial stromal cells: 12.5;Esophageal apical cells: 9.5;Fibro-adipogenic progenitors: 11.8;Hepatic stellate cells: 12.9;Leydig cells: 13.3;Ocular epithelial cells: 19.5;Papillary tip epithelial cells: 14.2;Prostatic hillock cells: 15.5;Schwann cells: 41.5;Suprabasal keratinocytes: 13.6;Urothelial cells: 16.3" "Cell type enriched" "Detected in many" 6 "thalamic excitatory: 43.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Spleen - B-cells (Spleen)" "HPA062460, HPA068731" Enhanced Vesicles NA NA "Cluster 58: Skin - Keratinization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 103: Non-specific - Basic cellular processes" Vesicles "HPA062460: , HPA068731: " "unprognostic (1.36e-1)" "unprognostic (3.52e-1)" "unprognostic (2.71e-1)" "unprognostic (4.74e-2)" "unprognostic (1.15e-3)" "unprognostic (5.03e-2)" "unprognostic (6.38e-3)" "unprognostic (1.61e-2)" "unprognostic (7.34e-3)" "unprognostic (1.18e-1)" "unprognostic (1.06e-1)" "validated prognostic unfavorable (8.31e-4)" "validated prognostic unfavorable (4.03e-6)" "unprognostic (1.67e-2)" "unprognostic (1.23e-2)" "unprognostic (1.49e-1)" CYP2A13 "CPAD, CYP2A" ENSG00000197838 "Cytochrome P450 family 2 subfamily A member 13" Q16696 19 41088451-41096195 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 10 "liver: 1.9" "Group enriched" "Detected in some" 4 "Conjunctival goblet cells: 109.7;Respiratory secretory cells: 74.0" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "Liver Hepatocellular Carcinoma (TCGA): 3.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes, Lung - Respiratory ciliated cells" "HPA046713, HPA047262" Supported "Intracellular and membrane" Enzyme NA NA "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 38: Secretory epithelial cells - Exocrine secretion" "HPA046713: , HPA047262: " "unprognostic (1.10e-1)" "unprognostic (1.48e-2)" CYP2A6 "CPA6, CYP2A, CYP2A3" ENSG00000255974 "Cytochrome P450 family 2 subfamily A member 6" P11509 19 40843541-40850447 "Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 170 "liver: 1507.9" "Cell type enriched" "Detected in some" 22 "Hepatocytes: 322.5" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 9 "Liver Hepatocellular Carcinoma (TCGA): 543.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes, Lung - Respiratory ciliated cells" "HPA046713, HPA047262" Supported NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 27: Breast cancer - Unknown function" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 1 "HPA046713: , HPA047262: " "unprognostic (1.47e-2)" "unprognostic (1.92e-1)" "unprognostic (2.28e-1)" "validated prognostic favorable (2.90e-4)" "validated prognostic favorable (2.99e-5)" "unprognostic (4.47e-3)" "unprognostic (1.03e-1)" "unprognostic (1.46e-1)" CYP2A7 CYP2A ENSG00000198077 "Cytochrome P450 family 2 subfamily A member 7" P20853 19 40875439-40882752 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 117 "liver: 162.8" "Cell type enriched" "Detected in some" 15 "Hepatocytes: 196.3" "Cell type enhanced" "Detected in single" "oligodendrocyte precursor cell: 1.1" "Group enriched" "Detected in some" 165 "Breast Invasive Carcinoma (TCGA): 25.8;Liver Hepatocellular Carcinoma (TCGA): 53.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes" "CAB033510, HPA046713, HPA047262" Enhanced "Intracellular and membrane" Enzyme NA NA "Cluster 53: Liver - Plasma proteins" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Breast cancer - Unknown function" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" "CAB033510: , HPA046713: , HPA047262: " "unprognostic (2.50e-1)" "unprognostic (5.73e-2)" "unprognostic (1.14e-3)" "unprognostic (1.46e-3)" CYP2B6 "CPB6, CYP2B, CYPIIB6" ENSG00000197408 "Cytochrome P450 family 2 subfamily B member 6" P20813 19 40991282-41018398 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 38 "liver: 549.6" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 1059.9" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 39.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 11.2;liver cancer: 18.0" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "CAB033866, HPA048124, HPA062973" Enhanced Approved "Nucleoplasm,Nuclear membrane,Cytosol" "Intracellular and membrane" Enzyme NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 48: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" "Nuclear membrane" "Nucleoplasm, Cytosol" "CAB033866: , HPA048124: , HPA062973: " "unprognostic (7.34e-2)" "unprognostic (4.87e-2)" "unprognostic (1.11e-1)" "unprognostic (1.44e-1)" "unprognostic (9.93e-2)" "unprognostic (3.26e-2)" "unprognostic (1.64e-2)" "unprognostic (2.69e-2)" "unprognostic (5.40e-2)" "potential prognostic favorable (2.17e-4)" "unprognostic (1.17e-3)" "unprognostic (3.57e-1)" "unprognostic (1.19e-1)" "unprognostic (7.95e-2)" CYP2C18 "CPCI, CYP2C, CYP2C17, P450IIC17" ENSG00000108242 "Cytochrome P450 family 2 subfamily C member 18" P33260 10 94683729-94736190 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 96.6;liver: 184.2;stomach 1: 63.5" "Cell type enhanced" "Detected in some" "Enterocytes: 12.4;Esophageal apical cells: 11.1;Esophageal basal cells: 2.8;Esophageal suprabasal cells: 13.3;Foveolar cells: 14.9;Hepatocytes: 3.4;Paneth cells: 3.9;Respiratory secretory cells: 4.1;Suprabasal keratinocytes: 5.7" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 38.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 13.3;liver cancer: 4.0" "Colon - Colon enterocytes, Liver - Hepatocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary gland basal cells, Pancreas - Ductal cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Not detected" "Not detected" HPA074424 Uncertain "Vesicles,Plasma membrane" "Intracellular and membrane" Enzyme NA NA "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 85: Squamous epithelial cells - Keratinization" 13 Vesicles "Plasma membrane" "HPA074424: " "unprognostic (2.80e-1)" "unprognostic (4.14e-2)" "unprognostic (1.25e-1)" "unprognostic (3.92e-1)" "unprognostic (9.03e-3)" "unprognostic (1.58e-1)" "unprognostic (1.79e-3)" "unprognostic (1.22e-2)" "unprognostic (8.48e-3)" "unprognostic (4.87e-3)" "unprognostic (5.69e-3)" "unprognostic (1.50e-3)" "unprognostic (1.04e-1)" "unprognostic (5.90e-2)" "unprognostic (9.80e-2)" "unprognostic (2.23e-1)" CYP2C19 "CPCJ, CYP2C, P450IIC19" ENSG00000165841 "Cytochrome P450 family 2 subfamily C member 19" P33261 10 94762681-94855547 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 178.0" "Cell type enhanced" "Detected in some" "Enterocytes: 21.8;Foveolar cells: 18.4;Hepatocytes: 84.9" "Cell type enhanced" "Detected in single" "deep-layer near-projecting: 1.0" "Cancer enhanced" "Detected in some" "Liver Hepatocellular Carcinoma (TCGA): 3.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes, Pancreas - Ductal cells, Stomach - Gastric mucous cells" "HPA015066, HPA074424" Supported Uncertain Vesicles "Intracellular and membrane" Enzyme NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 48: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 93: Hepatocytes - Bile production & excretion" 2 Vesicles "HPA015066: , HPA074424: " "unprognostic (1.12e-2)" "unprognostic (1.24e-1)" "potential prognostic favorable (1.24e-4)" "unprognostic (1.77e-1)" "unprognostic (5.82e-2)" "unprognostic (1.01e-1)" CYP2C8 CPC8 ENSG00000138115 "Cytochrome P450 family 2 subfamily C member 8" P10632 10 95036772-95069497 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 363 "liver: 2014.2" "Cell type enriched" "Detected in many" 17 "Hepatocytes: 2460.9" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in some" 84 "Liver Hepatocellular Carcinoma (TCGA): 145.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes, Spleen - B-cells (Spleen), Testis - Early spermatids, Testis - Late spermatids" "HPA013547, HPA013970, HPA015066, HPA074424" Enhanced Uncertain "Vesicles,Plasma membrane" NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 2 Vesicles "Plasma membrane" "HPA013547: , HPA013970: , HPA015066: , HPA074424: " "unprognostic (1.65e-1)" "unprognostic (4.61e-2)" "potential prognostic favorable (4.33e-4)" "unprognostic (4.02e-1)" "unprognostic (1.54e-3)" "potential prognostic favorable (2.09e-6)" "unprognostic (3.60e-3)" "unprognostic (3.26e-3)" "unprognostic (2.86e-1)" CYP2C9 "CYP2C10, P450IIC9" ENSG00000138109 "Cytochrome P450 family 2 subfamily C member 9" P11712 10 94938658-94990091 "Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "liver: 1607.6" "Cell type enriched" "Detected in some" 28 "Hepatocytes: 2814.4" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 43 "Liver Hepatocellular Carcinoma (TCGA): 165.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 1.6;liver cancer: 1.4;prostate cancer: 1.6" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Pancreas - Ductal cells, Stomach - Gastric mucous cells" "HPA015066, CAB016123, HPA074424" Enhanced Uncertain "Vesicles,Plasma membrane" "Intracellular and membrane" Enzyme NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 4 Vesicles "Plasma membrane" "CAB016123: , HPA015066: , HPA074424: " "unprognostic (6.06e-2)" "unprognostic (4.25e-1)" "validated prognostic unfavorable (5.42e-6)" "validated prognostic unfavorable (6.85e-4)" "unprognostic (2.20e-1)" "validated prognostic favorable (8.94e-7)" "validated prognostic favorable (5.80e-4)" "unprognostic (2.80e-2)" "unprognostic (1.39e-1)" "unprognostic (2.95e-1)" "unprognostic (9.03e-2)" CYP2D6 "CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, P450-DB1, P450C2D" ENSG00000100197 "Cytochrome P450 family 2 subfamily D member 6" P10635 22 42126499-42130865 "Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Cholesterol metabolism, Fatty acid metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 25 "liver: 386.2" "Group enriched" "Detected in some" 13 "Enterocytes: 212.7;Hepatocytes: 109.4" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in single" 159 "Liver Hepatocellular Carcinoma (TCGA): 47.8" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA045223 Enhanced Approved "Golgi apparatus" No No "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 15: Non-specific - Transcription" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 1: Enterocytes - Absorption and Digestion" "Golgi apparatus" "HPA045223: " "unprognostic (1.02e-1)" "unprognostic (1.44e-1)" "unprognostic (1.02e-1)" "unprognostic (3.21e-2)" "unprognostic (1.61e-2)" CYP2D7 "CYP2D, CYP2D@, CYP2D7P, CYP2D7P1" ENSG00000205702 "Cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene)" 22 42140203-42149455 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 30 "Enterocytes: 167.9" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 1: Enterocytes - Absorption and Digestion" CYP2E1 CYP2E ENSG00000130649 "Cytochrome P450 family 2 subfamily E member 1" P05181 10 133520406-133561220 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 307 "liver: 9697.0" "Cell type enriched" "Detected in many" 45 "Hepatocytes: 7806.9" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 292 "Liver Hepatocellular Carcinoma (TCGA): 1994.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 2.5;myeloid DC: 6.3" "Group enriched" "Detected in many" 16 "dendritic cells: 6.3;T-cells: 2.5" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA009128, HPA029564" Enhanced Approved "Endoplasmic reticulum,Mitochondria" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 37: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 93: Hepatocytes - Bile production & excretion" 2 "Endoplasmic reticulum, Mitochondria" "HPA009128: , HPA029564: " "unprognostic (1.62e-2)" "unprognostic (2.74e-1)" "unprognostic (5.20e-3)" "unprognostic (4.68e-3)" "unprognostic (5.63e-2)" "unprognostic (6.26e-3)" "unprognostic (1.75e-2)" "unprognostic (1.82e-2)" "potential prognostic unfavorable (2.08e-4)" "unprognostic (7.13e-2)" "unprognostic (2.33e-1)" "unprognostic (1.44e-3)" "unprognostic (1.27e-1)" "unprognostic (1.39e-2)" "unprognostic (9.72e-3)" "unprognostic (9.52e-2)" "unprognostic (2.03e-1)" "unprognostic (6.17e-2)" "unprognostic (7.86e-2)" "unprognostic (1.82e-1)" "unprognostic (5.52e-3)" "unprognostic (2.76e-2)" "unprognostic (1.22e-1)" "unprognostic (3.99e-2)" "unprognostic (1.05e-1)" "unprognostic (9.87e-2)" "unprognostic (3.77e-1)" "unprognostic (1.43e-1)" CYP2F1 CYP2F ENSG00000197446 "Cytochrome P450 family 2 subfamily F member 1" P24903 19 41114432-41128381 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lung: 1.1;testis: 1.8" "Group enriched" "Detected in some" 11 "Conjunctival goblet cells: 670.9;Respiratory deuterosomal cells: 283.0;Respiratory secretory cells: 399.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 2.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Intracellular and membrane" Enzyme NA NA "Cluster 39: Testis - Nuclear processes" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 38: Secretory epithelial cells - Exocrine secretion" "unprognostic (7.39e-2)" "unprognostic (7.02e-2)" "unprognostic (1.81e-1)" CYP2J2 ENSG00000134716 "Cytochrome P450 family 2 subfamily J member 2" P51589 1 59893308-59926773 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "heart muscle: 83.9;intestine: 78.5;liver: 136.7" "Cell type enhanced" "Detected in many" "Bergmann glia: 146.0;Cardiomyocytes: 306.1;Cytotrophoblasts: 134.8;Enterocytes: 149.6;Esophageal apical cells: 161.4;Hepatocytes: 69.0;Migrating cytotrophoblasts: 117.6;Myonuclei: 95.6;Oligodendrocytes: 80.2;Respiratory secretory cells: 96.6;Syncytiotrophoblasts: 311.7" "Cell type enhanced" "Detected in many" "astrocyte: 77.1;Bergmann glia: 181.5;oligodendrocyte: 127.4" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 112.6" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 2.9;naive CD8 T-cell: 2.6" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "colorectal cancer: 13.3" "Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Intracellular and membrane" Enzyme NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 76: Non-specific - Metabolism" "Cluster 38: Sub-cortical - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 3 "unprognostic (2.24e-1)" "unprognostic (9.84e-2)" "unprognostic (8.35e-2)" "unprognostic (1.33e-2)" "unprognostic (7.63e-2)" "unprognostic (3.20e-2)" "unprognostic (6.61e-2)" "unprognostic (3.35e-1)" "unprognostic (1.60e-1)" "validated prognostic favorable (2.04e-6)" "validated prognostic favorable (8.16e-7)" "potential prognostic unfavorable (6.44e-4)" "unprognostic (1.99e-1)" "potential prognostic favorable (9.77e-4)" "unprognostic (4.30e-2)" "unprognostic (1.70e-1)" "unprognostic (6.05e-2)" "unprognostic (9.72e-2)" "unprognostic (8.78e-2)" "unprognostic (2.41e-2)" "unprognostic (5.47e-2)" "unprognostic (1.37e-3)" "unprognostic (1.94e-1)" "unprognostic (5.26e-2)" "unprognostic (1.60e-3)" "unprognostic (2.55e-1)" "unprognostic (3.41e-1)" "unprognostic (7.17e-3)" CYP2R1 ENSG00000186104 "Cytochrome P450 family 2 subfamily R member 1" Q6VVX0 11 14877440-14892231 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" "Monooxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 97.2;Early spermatids: 216.7;Late primary spermatocytes: 105.8;Late spermatids: 146.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate basal glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA042949 Approved NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 49: Non-specific - Transcription" "Cluster 35: Non-specific - DNA binding" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" "HPA042949: " "unprognostic (8.26e-2)" "unprognostic (3.49e-1)" "unprognostic (8.08e-2)" "unprognostic (1.19e-3)" "unprognostic (1.00e-1)" "unprognostic (2.71e-1)" "unprognostic (2.76e-1)" "unprognostic (5.18e-2)" "unprognostic (2.69e-1)" "unprognostic (1.36e-3)" "unprognostic (3.03e-2)" "unprognostic (3.74e-3)" "unprognostic (2.41e-2)" "unprognostic (8.03e-2)" "unprognostic (2.31e-2)" "unprognostic (1.28e-1)" "unprognostic (1.97e-1)" "unprognostic (4.00e-2)" "unprognostic (1.83e-1)" "unprognostic (9.52e-2)" "unprognostic (2.17e-1)" "unprognostic (5.34e-2)" "unprognostic (1.18e-1)" "unprognostic (1.05e-1)" "unprognostic (1.11e-3)" "unprognostic (3.41e-2)" "unprognostic (4.68e-2)" "unprognostic (1.32e-2)" "unprognostic (1.33e-1)" "unprognostic (2.14e-3)" "unprognostic (2.87e-2)" CYP2S1 ENSG00000167600 "Cytochrome P450 family 2 subfamily S member 1" Q96SQ9 19 41193210-41207539 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Lyase, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "intestine: 95.3;stomach 1: 113.5" "Cell type enhanced" "Detected in many" "cDC: 61.0;Colonocytes: 26.8;Cytotrophoblasts: 31.1;Enterocytes: 58.4;Foveolar cells: 232.1;Goblet cells: 40.1;Paneth cells: 30.9;Respiratory basal cells: 45.9;Respiratory deuterosomal cells: 29.0" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 4.7;lower rhombic lip: 3.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "classical monocyte: 24.8;myeloid DC: 84.5" "Group enriched" "Detected in many" 131 "dendritic cells: 84.5;monocytes: 24.8" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adipose visceral - Mesothelial cells, Heart muscle - Macrophages, Pituitary gland - Undifferentiated cells (Pituitary gland), Spleen - Macrophages, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049227, HPA069248" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 77: Intestine - Digestion" "Cluster 49: Hindbrain - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 68: Foveolar cells - Mucosal defense" 2 "Endoplasmic reticulum" "HPA049227: , HPA069248: " "unprognostic (8.38e-2)" "unprognostic (8.59e-2)" "unprognostic (6.45e-2)" "unprognostic (1.89e-1)" "unprognostic (2.74e-2)" "unprognostic (1.53e-1)" "unprognostic (2.30e-1)" "potential prognostic unfavorable (7.30e-4)" "unprognostic (4.92e-2)" "unprognostic (6.13e-2)" "unprognostic (3.18e-1)" "unprognostic (6.71e-3)" "unprognostic (7.90e-3)" "unprognostic (1.69e-2)" "unprognostic (1.39e-1)" "unprognostic (9.71e-2)" "unprognostic (7.36e-3)" "unprognostic (2.85e-2)" "unprognostic (1.70e-2)" "unprognostic (1.49e-1)" "unprognostic (7.61e-3)" "unprognostic (8.07e-3)" "unprognostic (1.41e-1)" "unprognostic (1.50e-3)" "unprognostic (6.17e-3)" "unprognostic (2.09e-1)" "unprognostic (1.37e-1)" "unprognostic (1.42e-1)" "unprognostic (1.32e-1)" "unprognostic (1.52e-2)" CYP2U1 "SPG49, SPG56" ENSG00000155016 "Cytochrome P450 family 2 subfamily U member 1" Q7Z449 4 107931549-107953461 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism" "Monooxygenase, Oxidoreductase" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "lymphoid tissue: 79.0" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 74.5;Cardiomyocytes: 113.1;Melanocytes: 43.2;Schwann cells: 44.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Kidney - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041622, HPA046754, HPA064827" Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 80: Thymus - Adaptive immune response" "Cluster 55: Non-specific - Transcription" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" "Golgi apparatus" "Nucleoplasm, Vesicles" "HPA041622: , HPA046754: , HPA064827: " "unprognostic (4.50e-3)" "unprognostic (2.03e-1)" "unprognostic (4.74e-2)" "unprognostic (8.67e-2)" "unprognostic (1.97e-1)" "unprognostic (2.13e-2)" "unprognostic (2.46e-1)" "unprognostic (2.93e-2)" "unprognostic (1.04e-1)" "unprognostic (3.12e-2)" "potential prognostic favorable (1.24e-9)" "unprognostic (1.67e-2)" "unprognostic (2.00e-1)" "unprognostic (1.45e-2)" "unprognostic (2.94e-1)" "unprognostic (2.03e-3)" "unprognostic (2.24e-1)" "unprognostic (1.65e-1)" "unprognostic (6.50e-2)" "unprognostic (2.46e-3)" "unprognostic (2.83e-2)" "unprognostic (2.04e-3)" "potential prognostic favorable (4.91e-4)" "unprognostic (3.15e-1)" "unprognostic (4.12e-2)" "unprognostic (2.61e-1)" "unprognostic (3.20e-1)" "unprognostic (1.72e-2)" "unprognostic (4.11e-1)" "unprognostic (1.76e-2)" "unprognostic (1.43e-1)" CYP2W1 "FLJ20359, MGC34287" ENSG00000073067 "Cytochrome P450 family 2 subfamily W member 1" Q8TAV3 7 983181-989640 "Predicted intracellular proteins" "Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "adrenal gland: 18.7;intestine: 5.8;skin 1: 10.2" "Cell type enhanced" "Detected in some" "Adrenal cortex cells: 11.7;Enteric stem cells: 32.5;Enteric transient amplifying cells: 10.8;Fibroblasts: 7.2;Gastric progenitor cells: 51.3;Goblet cells: 11.3;Müller glia: 11.4;Neuroendocrine cells: 42.8;Prostatic hillock cells: 13.8" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 30.5;Rectum Adenocarcinoma (TCGA): 30.6;Stomach Adenocarcinoma (TCGA): 26.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "colorectal cancer: 10.7;Gastric cancer: 11.1" "Lung - Respiratory ciliated cells, Pituitary gland - Gonadotropes, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Not detected" "Not detected" "Intracellular and membrane" Enzyme NA NA "Cluster 37: Skin - Keratinization" "Cluster 6: Non-specific - Immune response" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" 6 "unprognostic (2.29e-2)" "unprognostic (4.04e-2)" "unprognostic (7.16e-2)" "unprognostic (2.84e-1)" "unprognostic (2.51e-1)" "unprognostic (4.41e-2)" "unprognostic (6.86e-2)" "unprognostic (4.35e-3)" "unprognostic (9.97e-2)" "unprognostic (7.52e-2)" "unprognostic (9.60e-2)" "unprognostic (1.41e-2)" "unprognostic (1.48e-1)" "unprognostic (4.14e-3)" "unprognostic (2.44e-1)" "unprognostic (1.33e-1)" "unprognostic (9.64e-2)" CYP39A1 ENSG00000146233 "Cytochrome P450 family 39 subfamily A member 1" Q9NYL5 6 46549580-46652830 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 92.8" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 65.9;Hepatocytes: 145.0;Prostatic glandular cells: 86.6;Sertoli cells: 92.7;Thyrotrophs: 69.4" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 33.2;endothelial cell: 30.1;ependymal cell: 37.1;fibroblast: 31.0" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 21.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Skin - Keratinocyte (other), Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Region enhanced" "Detected in all" "olfactory bulb: 22.9" "Low region specificity" "Detected in all" NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 93: Hepatocytes - Bile production & excretion" 1 "unprognostic (1.05e-1)" "unprognostic (6.56e-2)" "unprognostic (3.57e-1)" "unprognostic (3.50e-2)" "unprognostic (9.47e-2)" "unprognostic (1.70e-2)" "unprognostic (1.05e-1)" "unprognostic (1.21e-2)" "unprognostic (1.99e-1)" "unprognostic (3.07e-1)" "potential prognostic favorable (2.65e-4)" "unprognostic (1.04e-3)" "unprognostic (2.26e-1)" "unprognostic (1.49e-1)" "unprognostic (2.53e-3)" "unprognostic (3.03e-1)" "unprognostic (2.86e-2)" "unprognostic (4.69e-3)" "unprognostic (1.12e-2)" "unprognostic (1.18e-1)" "unprognostic (1.31e-1)" "unprognostic (1.51e-1)" "unprognostic (5.39e-2)" "unprognostic (1.27e-1)" "unprognostic (3.63e-2)" "unprognostic (4.77e-1)" "unprognostic (6.68e-2)" "unprognostic (8.72e-2)" "unprognostic (1.58e-1)" "unprognostic (1.17e-1)" CYP3A4 CYP3A3 ENSG00000160868 "Cytochrome P450 family 3 subfamily A member 4" P08684 7 99756960-99784248 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "liver: 3367.1" "Group enriched" "Detected in some" 64 "Enterocytes: 2039.8;Hepatocytes: 3988.6" "Cell type enhanced" "Detected in some" "Bergmann glia: 3.2" "Cancer enriched" "Detected in some" 59 "Liver Hepatocellular Carcinoma (TCGA): 470.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "CAB033671, HPA072245, HPA075539" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 53: Neurons - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 93: Hepatocytes - Bile production & excretion" 6 Cytosol Vesicles "CAB033671: , HPA072245: , HPA075539: " "unprognostic (1.81e-1)" "unprognostic (1.91e-1)" "validated prognostic favorable (9.13e-4)" "validated prognostic favorable (4.53e-6)" "unprognostic (5.97e-2)" "unprognostic (6.70e-2)" "unprognostic (3.13e-1)" CYP3A43 ENSG00000021461 "Cytochrome P450 family 3 subfamily A member 43" Q9HB55 7 99828013-99866093 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "liver: 38.6" "Cell type enriched" "Detected in some" 4 "Hepatocytes: 66.8" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in single" 13 "Liver Hepatocellular Carcinoma (TCGA): 3.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes, Prostate - Prostate glandular cells, Testis - Early spermatids" "HPA066463, HPA072245, HPA075539" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 53: Neurons - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 93: Hepatocytes - Bile production & excretion" Cytosol Vesicles "HPA066463: , HPA072245: , HPA075539: " "potential prognostic favorable (4.78e-4)" "unprognostic (2.38e-2)" CYP3A5 "CP35, P450PCN3, PCN3" ENSG00000106258 "Cytochrome P450 family 3 subfamily A member 5" P20815 7 99648194-99679998 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 167.3;liver: 319.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 647.1;Colonocytes: 613.5;Enterocytes: 1916.0;Esophageal apical cells: 396.9;Foveolar cells: 1066.6;Hepatocytes: 1064.0;Proximal tubule cells: 603.7;Urothelial cells: 674.9" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 147.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Adipocytes (Breast), Minor Salivary Gland - Minor salivary gland basal cells, Stomach - Gastric mucous cells" "HPA072245, HPA075539" Approved Vesicles,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 9: Non-specific - Receptor signaling" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 1: Enterocytes - Absorption and Digestion" 2 Cytosol Vesicles "HPA072245: , HPA075539: " "unprognostic (2.19e-2)" "unprognostic (2.29e-2)" "unprognostic (4.32e-2)" "unprognostic (2.65e-1)" "unprognostic (1.55e-1)" "unprognostic (3.05e-1)" "unprognostic (2.81e-2)" "unprognostic (2.46e-2)" "unprognostic (1.16e-1)" "unprognostic (2.63e-2)" "potential prognostic favorable (2.09e-4)" "unprognostic (5.33e-3)" "unprognostic (6.48e-2)" "validated prognostic favorable (8.78e-4)" "validated prognostic favorable (6.97e-6)" "unprognostic (5.63e-3)" "unprognostic (4.64e-2)" "unprognostic (2.96e-1)" "unprognostic (2.01e-1)" "unprognostic (1.56e-1)" "unprognostic (2.06e-1)" "unprognostic (3.01e-1)" "unprognostic (2.29e-1)" "unprognostic (1.63e-1)" "unprognostic (1.87e-1)" "unprognostic (2.84e-2)" "unprognostic (2.52e-2)" "unprognostic (3.81e-2)" "unprognostic (2.44e-1)" "unprognostic (1.07e-1)" "unprognostic (1.64e-1)" CYP3A7 "CP37, P450-HFLA" ENSG00000160870 "Cytochrome P450 family 3 subfamily A member 7" P24462 7 99705036-99735196 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 36 "liver: 285.4" "Cell type enriched" "Detected in single" 6 "Cholangiocytes: 5.9" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 8 "Liver Hepatocellular Carcinoma (TCGA): 96.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "breast cancer: 1.0" "Skin - Eccrine sweat gland cells" "HPA072245, HPA075539" Approved Vesicles,Cytosol NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 70: DU4475 - Unknown function" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 1 Cytosol Vesicles "HPA072245: , HPA075539: " "unprognostic (3.05e-2)" "unprognostic (6.98e-2)" "potential prognostic favorable (4.55e-13)" "unprognostic (2.12e-3)" "unprognostic (1.36e-1)" "unprognostic (2.60e-2)" "unprognostic (2.59e-2)" "unprognostic (1.18e-1)" CYP3A7-CYP3A51P ENSG00000282301 "CYP3A7-CYP3A51P readthrough" 7 99684957-99735102 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "liver: 11.9" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 11.1;Cholangiocytes: 12.5;Hepatocytes: 18.0" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "Liver Hepatocellular Carcinoma (TCGA): 4.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA072245, HPA075539" Approved Vesicles,Cytosol NA NA "Cluster 16: Liver & Kidney - Metabolism" "Cluster 53: Neurons - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" Cytosol Vesicles "HPA072245: , HPA075539: " "unprognostic (1.12e-1)" CYP46A1 CYP46 ENSG00000036530 "Cytochrome P450 family 46 subfamily A member 1" Q9Y6A2 14 99684298-99727301 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "brain: 159.2" "Cell type enhanced" "Detected in many" "Astrocytes: 89.0;Brain excitatory neurons: 66.7;Brain inhibitory neurons: 134.7;Choroid plexus epithelial cells: 61.6;Cone photoreceptor cells: 95.2;Lactotrophs: 64.9;Other brain neurons: 64.3;pDCs: 96.1;Rod photoreceptor cells: 64.9;Somatotrophs: 163.2;Thyrotrophs: 102.2" "Cell type enhanced" "Detected in all" "medium spiny neuron: 271.1" "Cancer enriched" "Detected in some" 7 "Glioblastoma Multiforme (TCGA): 11.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 23 "plasmacytoid DC: 3.4" "Lineage enriched" "Detected in single" 23 "dendritic cells: 3.4" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 35: Neurons - Synaptic function & neurogenesis" "unprognostic (2.37e-1)" "unprognostic (1.65e-1)" "unprognostic (8.20e-2)" "potential prognostic unfavorable (2.62e-4)" "unprognostic (8.67e-3)" "unprognostic (2.72e-1)" CYP4A11 "CYP4A2, CYP4AII" ENSG00000187048 "Cytochrome P450 family 4 subfamily A member 11" Q02928 1 46929177-46941484 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 344 "kidney: 202.9;liver: 794.7" "Cell type enriched" "Detected in some" 4 "Hepatocytes: 678.5" "Cell type enhanced" "Detected in single" "pericyte: 1.3" "Group enriched" "Detected in some" 17 "Kidney Renal Clear Cell Carcinoma (TCGA): 55.6;Liver Hepatocellular Carcinoma (TCGA): 147.4" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" NA NA "Cluster 16: Liver & Kidney - Metabolism" "Cluster 1: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 93: Hepatocytes - Bile production & excretion" "unprognostic (7.63e-2)" "validated prognostic favorable (7.86e-8)" "validated prognostic favorable (1.15e-6)" "unprognostic (2.03e-1)" "unprognostic (1.69e-2)" "potential prognostic favorable (1.44e-4)" CYP4A22 ENSG00000162365 "Cytochrome P450 family 4 subfamily A member 22" Q5TCH4 1 47137435-47149727 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "liver: 199.9" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 149.6" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "Liver Hepatocellular Carcinoma (TCGA): 44.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 93: Hepatocytes - Bile production & excretion" "validated prognostic favorable (2.14e-7)" "validated prognostic favorable (8.16e-6)" "unprognostic (3.40e-3)" "potential prognostic favorable (9.22e-5)" "unprognostic (2.91e-2)" CYP4B1 ENSG00000142973 "Cytochrome P450 family 4 subfamily B member 1" P13584 1 46757838-46819413 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 227.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 313.2;Alveolar cells type 2: 122.3;Decidual stromal cells: 178.8;Esophageal suprabasal cells: 139.5;Fallopian tube ciliated cells: 197.9;Papillary tip epithelial cells: 120.7;Prostatic hillock cells: 214.3;Respiratory basal cells: 186.7;Respiratory ciliated cells: 764.7;Respiratory deuterosomal cells: 280.9;Respiratory secretory cells: 446.9;Transitional alveolar cells: 260.4;Urothelial cells: 138.6" "Group enriched" "Detected in some" 4 "endothelial cell: 7.0;ependymal cell: 1.8;fibroblast: 6.4" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 84.1;Lung Adenocarcinoma (TCGA): 69.0" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "Bladder cancer: 12.1;breast cancer: 28.8" "Breast - Adipocytes (Breast), Lung - Alveolar cells type 1, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA004331 Approved Supported Vesicles NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 27: Breast cancer - Unknown function" "Cluster 108: Fibroblasts - ECM organization" Vesicles "HPA004331: " "unprognostic (1.12e-2)" "potential prognostic unfavorable (4.65e-4)" "unprognostic (2.69e-1)" "unprognostic (1.36e-2)" "unprognostic (3.78e-1)" "unprognostic (1.28e-1)" "unprognostic (5.20e-1)" "potential prognostic favorable (4.72e-5)" "unprognostic (1.37e-2)" "unprognostic (2.32e-2)" "unprognostic (2.58e-1)" "unprognostic (3.82e-1)" "unprognostic (1.38e-3)" "unprognostic (7.24e-2)" "unprognostic (5.83e-2)" "unprognostic (1.87e-1)" "unprognostic (2.98e-1)" "unprognostic (9.26e-3)" "unprognostic (6.54e-2)" CYP4F11 ENSG00000171903 "Cytochrome P450 family 4 subfamily F member 11" Q9HBI6 19 15912367-15934867 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 22.4;liver: 67.3" "Cell type enhanced" "Detected in many" "Astrocytes: 16.1;Bergmann glia: 19.6;Cholangiocytes: 17.3;Epididymal principal cells: 20.6;Esophageal apical cells: 23.0;Hepatocytes: 68.2;Ocular epithelial cells: 18.8;Prostatic hillock cells: 24.2;Urothelial cells: 63.5" "Group enriched" "Detected in some" 6 "astrocyte: 20.8;Bergmann glia: 18.3" "Cancer enhanced" "Detected in many" "Lung Squamous Cell Carcinoma (TCGA): 52.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Gallbladder cancer: 217.7" "Liver - Hepatocytes, Prostate - Prostate basal glandular cells" "HPA017265, CAB033648, HPA058960" Enhanced NA NA "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 39: Astrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 69: Urothelial cells - Basic cellular functions" 1 "CAB033648: , HPA017265: , HPA058960: " "unprognostic (7.56e-2)" "potential prognostic favorable (8.37e-5)" "unprognostic (2.89e-1)" "unprognostic (1.34e-1)" "unprognostic (1.26e-1)" "unprognostic (5.95e-3)" "unprognostic (1.51e-2)" "unprognostic (1.28e-3)" "unprognostic (7.88e-3)" "unprognostic (1.20e-1)" "unprognostic (2.56e-1)" "unprognostic (5.24e-2)" "potential prognostic unfavorable (4.74e-4)" "unprognostic (1.61e-1)" "unprognostic (7.56e-3)" "unprognostic (9.05e-2)" "unprognostic (5.74e-2)" "unprognostic (3.35e-1)" "unprognostic (1.30e-1)" "unprognostic (1.00e-1)" "unprognostic (7.27e-2)" "potential prognostic unfavorable (4.83e-4)" "unprognostic (2.59e-1)" "unprognostic (3.18e-1)" "unprognostic (1.58e-1)" "unprognostic (1.18e-1)" "unprognostic (5.80e-3)" "unprognostic (3.65e-2)" "unprognostic (1.62e-1)" CYP4F12 ENSG00000186204 "Cytochrome P450 family 4 subfamily F member 12" Q9HCS2 19 15673018-15697174 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 39.1;liver: 41.4" "Cell type enhanced" "Detected in many" "Colonocytes: 76.1;Conjunctival goblet cells: 38.8;Enteric transient amplifying cells: 47.2;Enterocytes: 171.0;Esophageal basal cells: 43.8;Esophageal suprabasal cells: 60.5;Foveolar cells: 84.9;Goblet cells: 39.0;Hepatocytes: 41.6;Prostatic club cells: 74.0;Prostatic hillock cells: 95.5;Salivary duct cells: 39.0;Suprabasal keratinocytes: 51.4;Urothelial cells: 39.6" "Cell type enriched" "Detected in some" 4 "astrocyte: 28.7" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 16.5" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 54 "basophil: 6.2;eosinophil: 14.9" "Lineage enriched" "Detected in single" 88 "granulocytes: 14.9" "Cancer enhanced" "Detected in many" "colorectal cancer: 5.0;Gastric cancer: 5.6" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Urothelial cells, Stomach - Gastric mucous cells, Thyroid gland - Fibroblasts" HPA058960 Approved NA NA "Cluster 41: Basophils - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 46: Brainstem - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 1: Enterocytes - Absorption and Digestion" 2 "HPA058960: " "unprognostic (1.06e-2)" "unprognostic (1.01e-3)" "potential prognostic favorable (7.40e-4)" "potential prognostic favorable (1.50e-4)" "unprognostic (1.62e-1)" "unprognostic (6.21e-2)" "unprognostic (9.02e-2)" "unprognostic (7.32e-3)" "unprognostic (6.31e-2)" "unprognostic (4.64e-2)" "unprognostic (5.77e-3)" "unprognostic (1.40e-1)" "unprognostic (6.04e-2)" "unprognostic (4.17e-2)" "unprognostic (1.56e-1)" "unprognostic (3.84e-2)" "unprognostic (1.68e-1)" "unprognostic (1.74e-1)" "unprognostic (3.20e-1)" "unprognostic (2.11e-1)" "unprognostic (1.40e-1)" CYP4F2 ENSG00000186115 "Cytochrome P450 family 4 subfamily F member 2" P78329 19 15878023-15898077 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 75.6;kidney: 38.2;liver: 155.9" "Group enriched" "Detected in some" 5 "Enterocytes: 209.3;Epididymal principal cells: 58.6;Hepatocytes: 153.9" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 8 "Liver Hepatocellular Carcinoma (TCGA): 47.1" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 19 "basophil: 8.1" "Lineage enriched" "Detected in single" 81 "granulocytes: 8.1" "Cancer enhanced" "Detected in some" "colorectal cancer: 1.8;Gastric cancer: 1.2" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "HPA014048, HPA017265, HPA058960" Supported NA NA "Cluster 41: Basophils - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 39: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 1: Enterocytes - Absorption and Digestion" 33 "HPA014048: , HPA017265: , HPA058960: " "unprognostic (2.00e-1)" "unprognostic (2.70e-2)" "unprognostic (5.48e-3)" "potential prognostic favorable (8.44e-6)" "unprognostic (3.82e-1)" "unprognostic (9.48e-2)" "unprognostic (1.31e-1)" "unprognostic (2.40e-2)" "unprognostic (4.25e-1)" CYP4F22 FLJ39501 ENSG00000171954 "Cytochrome P450 family 4 subfamily F member 22" Q6NT55 19 15508525-15552317 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism" "Monooxygenase, Oxidoreductase" Ichthyosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 18.7;skin 1: 55.8;vagina: 21.5" "Cell type enhanced" "Detected in some" "Breast hormone-responsive cells: 23.9;Esophageal apical cells: 112.0;Esophageal suprabasal cells: 31.3;Prostatic club cells: 14.1;Prostatic glandular cells: 44.0;Prostatic hillock cells: 19.0;Suprabasal keratinocytes: 30.1;Urothelial cells: 37.6" "Cell type enriched" "Detected in some" 5 "leukocyte: 8.4" "Group enriched" "Detected in many" 6 "Bladder Urothelial Carcinoma (TCGA): 18.1;Breast Invasive Carcinoma (TCGA): 7.3;Head and Neck Squamous Cell Carcinoma (TCGA): 7.9;Liver Hepatocellular Carcinoma (TCGA): 11.1;Skin Cutaneous Melanoma (TCGA): 6.8" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "intermediate monocyte: 6.1;MAIT T-cell: 4.3;non-classical monocyte: 14.2" "Group enriched" "Detected in many" 8 "monocytes: 14.2;T-cells: 4.3" "Cancer enriched" "Detected in some" 31 "Bone cancer: 42.8" "Lung - T-cells, Skin - Keratinocyte (granular), Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" HPA058960 Uncertain NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 58: Skin - Keratinization" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 85: Squamous epithelial cells - Keratinization" 11 "HPA058960: " "unprognostic (1.28e-3)" "unprognostic (4.64e-3)" "unprognostic (7.02e-3)" "unprognostic (5.66e-2)" "unprognostic (1.22e-1)" "unprognostic (1.20e-1)" "unprognostic (1.32e-2)" "unprognostic (1.78e-1)" "unprognostic (1.75e-1)" "unprognostic (1.67e-1)" CYP4F3 "CYP4F, LTB4H" ENSG00000186529 "Cytochrome P450 family 4 subfamily F member 3" Q08477 19 15640897-15662825 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 75.8;liver: 217.9" "Group enriched" "Detected in many" 5 "Hepatocytes: 696.6;Neutrophil progenitors: 959.7;Neutrophils: 443.3" "Cell type enriched" "Detected in some" 13 "astrocyte: 36.8" "Group enriched" "Detected in many" 4 "Liver Hepatocellular Carcinoma (TCGA): 51.9;Lung Squamous Cell Carcinoma (TCGA): 31.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 63 "neutrophil: 84.2" "Lineage enriched" "Detected in single" 179 "granulocytes: 84.2" "Cancer enriched" "Detected in many" 7 "Gallbladder cancer: 102.4" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Urothelial cells, Stomach - Gastric mucous cells, Thyroid gland - Neutrophils" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA058960 Approved NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 53: Liver - Plasma proteins" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 48: Neutrophils - Phagocytosis & degranulation" "HPA058960: " "unprognostic (2.29e-2)" "unprognostic (4.70e-2)" "unprognostic (1.04e-2)" "unprognostic (8.97e-2)" "unprognostic (5.44e-2)" "unprognostic (2.69e-1)" "unprognostic (5.73e-3)" "unprognostic (2.62e-1)" "unprognostic (4.30e-2)" "unprognostic (9.67e-2)" "unprognostic (6.39e-2)" "unprognostic (4.87e-2)" "unprognostic (1.42e-3)" "unprognostic (4.00e-3)" "unprognostic (1.69e-1)" "unprognostic (1.48e-1)" "unprognostic (4.55e-2)" "unprognostic (1.32e-2)" "unprognostic (1.76e-1)" "unprognostic (2.92e-2)" "unprognostic (1.61e-1)" "unprognostic (2.37e-1)" "unprognostic (6.08e-2)" "unprognostic (1.20e-1)" "unprognostic (5.10e-2)" CYP4F8 ENSG00000186526 "Cytochrome P450 family 4 subfamily F member 8" P98187 19 15615218-15630639 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "seminal vesicle: 202.7" "Cell type enhanced" "Detected in some" "Breast hormone-responsive cells: 2.9;Late spermatids: 1.2;Medullary thymic epithelial cells: 2.4;Papillary tip epithelial cells: 2.6;Prostatic club cells: 2.2;Prostatic glandular cells: 1.7;Prostatic hillock cells: 5.4;Urothelial cells: 6.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder Urothelial Carcinoma (TCGA): 16.2;Prostate Adenocarcinoma (TCGA): 6.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 29 "prostate cancer: 13.7" "Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058960 Approved NA NA "Cluster 38: Non-specific - Basic cellular processes" "Cluster 60: Prostate cancer - Unknown function" "Cluster 69: Urothelial cells - Basic cellular functions" "HPA058960: " "unprognostic (1.33e-3)" "unprognostic (3.24e-2)" "unprognostic (1.86e-1)" "unprognostic (1.39e-2)" "unprognostic (4.00e-2)" CYP4V2 CYP4AH1 ENSG00000145476 "Cytochrome P450 family 4 subfamily V member 2" Q6ZWL3 4 186191567-186213463 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism, Sensory transduction, Vision" "Monooxygenase, Oxidoreductase" "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 106.1" "Cell type enhanced" "Detected in many" "Astrocytes: 68.3;Müller glia: 73.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029122 Approved Approved "Nuclear speckles" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 8: Immune cells - Immune response" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 20: Non-specific - Transcription regulation" 1 "Nuclear speckles" "HPA029122: " "unprognostic (2.22e-1)" "unprognostic (2.13e-1)" "unprognostic (2.25e-1)" "unprognostic (2.19e-1)" "unprognostic (1.45e-1)" "unprognostic (1.07e-1)" "unprognostic (4.44e-1)" "unprognostic (1.85e-2)" "unprognostic (2.65e-1)" "unprognostic (3.67e-2)" "validated prognostic favorable (2.84e-14)" "validated prognostic favorable (3.67e-6)" "unprognostic (2.15e-2)" "unprognostic (2.51e-3)" "potential prognostic favorable (2.15e-4)" "unprognostic (1.56e-1)" "unprognostic (3.48e-2)" "unprognostic (2.18e-3)" "unprognostic (8.03e-2)" "unprognostic (3.76e-2)" "unprognostic (4.76e-2)" "unprognostic (1.70e-1)" "unprognostic (2.81e-1)" "unprognostic (1.58e-1)" "unprognostic (3.71e-2)" "unprognostic (5.28e-2)" "unprognostic (1.59e-2)" "unprognostic (3.02e-2)" "unprognostic (1.06e-1)" "unprognostic (1.71e-2)" "unprognostic (9.83e-2)" CYP4X1 MGC40051 ENSG00000186377 "Cytochrome P450 family 4 subfamily X member 1" Q8N118 1 47023669-47050751 "Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 34.9" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 81.6;Endometrial secretory cells: 71.3;Fibro-adipogenic progenitors: 92.5;Gastric chief cells: 67.7;Mucous neck cells: 57.2;Respiratory basal cells: 61.2;Respiratory ciliated cells: 105.1;Respiratory deuterosomal cells: 68.4;Respiratory secretory cells: 61.6;Salivary basal cells: 64.6;Submucosal glandular cells: 114.0" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 43.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 8.2;prostate cancer: 11.6" "Kidney - Fibroblasts, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary gland ductal cells, Skeletal muscle - Fibroblasts, Stomach - Chief cells, Testis - Peritubular cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017661 Approved NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 38: Secretory epithelial cells - Exocrine secretion" "HPA017661: " "unprognostic (2.83e-2)" "unprognostic (3.73e-2)" "unprognostic (5.48e-3)" "unprognostic (1.48e-1)" "unprognostic (2.22e-1)" "unprognostic (3.63e-2)" "unprognostic (6.40e-2)" "unprognostic (2.49e-3)" "unprognostic (1.04e-2)" "validated prognostic favorable (5.63e-6)" "validated prognostic favorable (4.74e-5)" "unprognostic (2.12e-1)" "unprognostic (4.14e-2)" "unprognostic (8.33e-3)" "unprognostic (2.31e-1)" "unprognostic (1.26e-1)" "unprognostic (7.05e-2)" "unprognostic (7.22e-2)" "unprognostic (2.65e-1)" "unprognostic (2.04e-1)" "unprognostic (1.28e-1)" "unprognostic (9.92e-2)" "unprognostic (3.25e-1)" "unprognostic (2.03e-2)" "unprognostic (6.77e-3)" "unprognostic (1.52e-1)" "unprognostic (1.68e-1)" "unprognostic (7.93e-2)" CYP4Z1 CYP4A20 ENSG00000186160 "Cytochrome P450 family 4 subfamily Z member 1" Q86W10 1 47067231-47118318 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 5.2" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 21.6;Breast myoepithelial cells: 37.0;Epicardial cells: 34.1;Fibro-adipogenic progenitors: 53.7;Prostatic hillock cells: 13.0;Retinal ganglion cells: 15.5" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in some" 64 "Breast Invasive Carcinoma (TCGA): 69.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "breast cancer: 2.1;lymphoma: 3.7" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 50: Lymphoma - Unknown function" "Cluster 108: Fibroblasts - ECM organization" "unprognostic (4.49e-2)" "unprognostic (4.33e-1)" "unprognostic (2.75e-1)" "unprognostic (1.80e-2)" CYP51A1 "CP51, CYP51, CYPL1, LDM, P450-14DM, P450L1" ENSG00000001630 "Cytochrome P450 family 51 subfamily A member 1" Q16850 7 92084987-92134803 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "Monooxygenase, Oxidoreductase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 188.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 322.6;Early spermatids: 159.9;Epicardial cells: 282.0;Late spermatids: 142.7;Myonuclei: 80.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary gland basal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041325, HPA043508" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 76: Non-specific - Metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 14 "Endoplasmic reticulum" "HPA041325: , HPA043508: " "unprognostic (4.11e-2)" "unprognostic (1.18e-1)" "unprognostic (6.94e-2)" "potential prognostic unfavorable (3.28e-5)" "unprognostic (2.94e-3)" "unprognostic (1.37e-1)" "unprognostic (1.32e-1)" "unprognostic (1.64e-3)" "unprognostic (1.01e-3)" "potential prognostic unfavorable (7.26e-4)" "potential prognostic favorable (5.89e-9)" "unprognostic (8.45e-2)" "unprognostic (3.05e-1)" "unprognostic (7.08e-2)" "unprognostic (2.72e-2)" "unprognostic (5.01e-2)" "unprognostic (2.60e-1)" "unprognostic (2.30e-1)" "unprognostic (2.67e-2)" "unprognostic (2.18e-1)" "unprognostic (1.24e-1)" "unprognostic (1.52e-1)" "unprognostic (2.95e-1)" "unprognostic (4.34e-2)" "unprognostic (1.56e-1)" "unprognostic (8.78e-2)" "unprognostic (1.78e-1)" "unprognostic (1.04e-1)" "unprognostic (4.28e-1)" "unprognostic (4.86e-2)" "unprognostic (7.71e-2)" CYP7A1 CYP7 ENSG00000167910 "Cytochrome P450 family 7 subfamily A member 1" P22680 8 58490178-58500163 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 112 "liver: 46.3" "Cell type enriched" "Detected in single" 21 "Hepatocytes: 10.3" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 79 "Liver Hepatocellular Carcinoma (TCGA): 36.4" "Region enhanced" "Detected in single" "cerebral cortex: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 12: Non-specific - Vasculature" "Cluster 93: Hepatocytes - Bile production & excretion" "potential prognostic favorable (4.83e-4)" "unprognostic (7.94e-2)" CYP7B1 SPG5A ENSG00000172817 "Cytochrome P450 family 7 subfamily B member 1" O75881 8 64587763-64798737 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Disease variant, Hereditary spastic paraplegia, Intrahepatic cholestasis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 285.9;Fibro-adipogenic progenitors: 167.4;Pituicytes/FSCs: 171.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "basophil: 2.5;eosinophil: 1.5" "Lineage enriched" "Detected in single" 25 "granulocytes: 2.5" "Cancer enhanced" "Detected in some" "skin cancer: 2.7" "Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017761 Uncertain NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 110: Mural cells - ECM organization" 1 "HPA017761: " "unprognostic (8.62e-3)" "unprognostic (7.02e-3)" "unprognostic (5.36e-2)" "unprognostic (5.92e-2)" "unprognostic (1.35e-1)" "unprognostic (3.30e-1)" "unprognostic (3.40e-2)" "unprognostic (3.06e-2)" "unprognostic (2.54e-2)" "unprognostic (3.09e-2)" "potential prognostic favorable (6.39e-6)" "unprognostic (1.28e-1)" "unprognostic (1.11e-2)" "unprognostic (5.74e-2)" "unprognostic (1.13e-2)" "unprognostic (1.81e-1)" "unprognostic (1.03e-1)" "unprognostic (3.04e-2)" "unprognostic (1.32e-2)" "unprognostic (9.39e-2)" "unprognostic (4.26e-1)" "unprognostic (2.83e-1)" "unprognostic (5.68e-2)" "unprognostic (1.72e-1)" "unprognostic (1.33e-3)" "unprognostic (1.71e-3)" "unprognostic (4.30e-3)" "unprognostic (1.65e-1)" "unprognostic (1.79e-2)" CYP8B1 CYP12 ENSG00000180432 "Cytochrome P450 family 8 subfamily B member 1" Q9UNU6 3 42856005-42875898 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 28 "liver: 378.2" "Cell type enriched" "Detected in some" 16 "Hepatocytes: 1053.6" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 5.2;fibroblast: 3.2" "Cancer enriched" "Detected in some" 28 "Liver Hepatocellular Carcinoma (TCGA): 100.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 53: Liver - Plasma proteins" "Cluster 29: Forebrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 93: Hepatocytes - Bile production & excretion" "unprognostic (1.73e-3)" "unprognostic (7.76e-3)" "unprognostic (5.84e-2)" "unprognostic (2.57e-3)" "potential prognostic favorable (1.24e-4)" CYREN "C7orf49, FLJ22450, FLJ27285, MGC5242, MRI, MRI-2" ENSG00000122783 "Cell cycle regulator of NHEJ" Q9BWK5 7 135092363-135170795 "Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 196.0;Platelets: 159.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020060 Approved NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 30: White matter - Myelination" "Cluster 39: Non-specific - Transcription" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 3 "HPA020060: " "unprognostic (1.76e-2)" "unprognostic (1.40e-1)" "unprognostic (2.22e-3)" "unprognostic (3.48e-2)" "unprognostic (2.79e-2)" "unprognostic (7.28e-2)" "unprognostic (5.01e-2)" "unprognostic (3.04e-2)" "potential prognostic unfavorable (5.50e-5)" "unprognostic (6.03e-3)" "unprognostic (4.38e-2)" "unprognostic (1.99e-1)" "potential prognostic unfavorable (4.21e-6)" "potential prognostic unfavorable (1.35e-4)" "unprognostic (6.81e-2)" "unprognostic (2.73e-1)" "unprognostic (1.39e-1)" "unprognostic (3.18e-2)" "unprognostic (7.10e-2)" "unprognostic (5.99e-2)" "unprognostic (2.37e-2)" "unprognostic (1.07e-1)" "unprognostic (7.75e-2)" "unprognostic (6.15e-2)" "unprognostic (1.35e-2)" "unprognostic (2.41e-1)" "unprognostic (1.62e-1)" "unprognostic (6.36e-3)" "unprognostic (1.01e-1)" CYRIA "CYRI-A, DKFZP566A1524, FAM49A, FLJ11080" ENSG00000197872 "CYFIP related Rac1 interactor A" Q9H0Q0 2 16549459-16666331 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 46.1" "Cell type enhanced" "Detected in many" "B-cells: 292.1;cDC: 630.5;Kupffer cells: 437.6;Macrophages: 402.8;monocytes: 818.3;Neutrophils: 940.2;Plasma cells: 358.8;Syncytiotrophoblasts: 292.7" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Thyroid Carcinoma (TCGA): 30.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Neuroblastoma: 75.0" "Heart muscle - Fibroblasts, Skin - Hair cortex cells, Skin - Inner root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017847, HPA060398" Approved Approved Nucleoplasm NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 73: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 82: Dendritic cells - Antigen presentation" 2 Nucleoplasm "CAB017847: , HPA060398: " "unprognostic (4.29e-2)" "unprognostic (1.97e-1)" "unprognostic (3.65e-2)" "unprognostic (2.68e-2)" "unprognostic (2.04e-1)" "unprognostic (1.80e-1)" "unprognostic (7.93e-2)" "unprognostic (4.69e-2)" "unprognostic (1.87e-1)" "unprognostic (3.50e-3)" "unprognostic (6.94e-3)" "unprognostic (1.82e-2)" "unprognostic (2.74e-2)" "unprognostic (1.08e-2)" "unprognostic (1.48e-1)" "unprognostic (8.14e-2)" "unprognostic (6.04e-3)" "unprognostic (7.09e-3)" "unprognostic (2.46e-3)" "unprognostic (4.63e-2)" "unprognostic (7.48e-2)" "unprognostic (2.04e-1)" "unprognostic (1.55e-1)" "unprognostic (3.27e-2)" "unprognostic (8.05e-2)" "unprognostic (1.19e-2)" "unprognostic (4.96e-2)" "unprognostic (5.12e-2)" "unprognostic (7.18e-2)" CYRIB "BM-009, CYRI, CYRI-B, FAM49B" ENSG00000153310 "CYFIP related Rac1 interactor B" Q9NUQ9 8 129839593-130017504 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 187.0" "Cell type enhanced" "Detected in all" "Microglia: 1238.3;Neutrophil progenitors: 1952.8;Neutrophils: 6072.3" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 1547.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Lung - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009076 Enhanced Approved Nucleoplasm,Cytosol NA NA 1400000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 30: White matter - Myelination" "Cluster 40: Non-specific - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 24 Nucleoplasm Cytosol "HPA009076: " "unprognostic (1.77e-1)" "unprognostic (4.32e-2)" "unprognostic (3.42e-3)" "unprognostic (3.14e-1)" "unprognostic (4.00e-2)" "unprognostic (1.33e-2)" "unprognostic (3.56e-3)" "unprognostic (2.07e-2)" "unprognostic (3.61e-2)" "unprognostic (3.35e-3)" "unprognostic (2.46e-1)" "unprognostic (4.10e-3)" "potential prognostic unfavorable (2.63e-7)" "unprognostic (3.08e-2)" "potential prognostic unfavorable (7.16e-4)" "unprognostic (1.57e-1)" "unprognostic (1.09e-1)" "unprognostic (1.23e-1)" "unprognostic (2.99e-1)" "unprognostic (3.26e-2)" "potential prognostic unfavorable (2.69e-4)" "unprognostic (2.54e-1)" "unprognostic (3.36e-1)" "unprognostic (2.60e-3)" "unprognostic (2.43e-1)" "unprognostic (1.43e-1)" "unprognostic (1.07e-1)" "unprognostic (4.75e-2)" "unprognostic (2.09e-2)" CYS1 ENSG00000205795 "Cystin 1" Q717R9 2 10056473-10080944 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "kidney: 117.2" "Cell type enhanced" "Detected in many" "Cholangiocytes: 46.5;Choroid plexus epithelial cells: 70.4;Distal convoluted tubule cells: 273.5;Loop of henle epithelial cells: 177.9;Pancreatic duct cells: 115.8;Proximal tubule cells: 78.8;Renal collecting duct principal cells: 97.5;Renal connecting tubule cells: 185.6" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 46.8" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 133.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 5.9" "Liver - Hepatic stellate cells, Minor Salivary Gland - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Testis - Peritubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 8: Immune cells - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 12 "unprognostic (4.79e-2)" "unprognostic (1.35e-1)" "unprognostic (3.35e-3)" "unprognostic (1.95e-2)" "unprognostic (2.53e-2)" "unprognostic (1.18e-1)" "unprognostic (1.74e-1)" "unprognostic (3.11e-1)" "potential prognostic favorable (1.91e-10)" "unprognostic (3.10e-3)" "unprognostic (1.22e-2)" "unprognostic (1.17e-1)" "unprognostic (1.64e-1)" "unprognostic (9.00e-2)" "unprognostic (1.59e-1)" "unprognostic (6.62e-2)" "unprognostic (3.13e-1)" "unprognostic (9.74e-2)" "unprognostic (8.02e-2)" "unprognostic (5.89e-2)" "unprognostic (9.94e-2)" "unprognostic (2.03e-1)" "unprognostic (4.82e-2)" "unprognostic (7.71e-3)" "unprognostic (1.50e-3)" "unprognostic (1.25e-1)" "unprognostic (9.83e-2)" "unprognostic (1.49e-2)" CYSLTR1 "CysLT(1), CysLT1, CYSLT1R" ENSG00000173198 "Cysteinyl leukotriene receptor 1" Q9Y271 X 78271468-78327691 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 10.9" "Cell type enhanced" "Detected in many" "B-cells: 89.8;Hematopoietic stem cells: 46.1;Hofbauer cells: 67.7;Innate lymphoid cells: 129.5;Kupffer cells: 61.5;Macrophages: 35.6;Mast cells: 61.9;Microglia: 82.2;pDCs: 128.7;Plasma cells: 89.5;Thymic myoid cells: 34.0;Thymocytes: 66.1" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 107.0;endothelial cell: 47.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 85.9" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 13 "Leukemia: 7.9;lymphoma: 3.5;Myeloma: 7.0" "Adrenal gland - Fibroblasts, Breast - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA010546 Approved NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 3 "HPA010546: " "unprognostic (1.95e-1)" "unprognostic (1.70e-1)" "unprognostic (2.07e-1)" "potential prognostic favorable (2.20e-4)" "unprognostic (2.73e-1)" "unprognostic (7.16e-2)" "unprognostic (2.67e-1)" "potential prognostic favorable (4.83e-6)" "unprognostic (1.81e-2)" "unprognostic (4.92e-2)" "unprognostic (1.78e-3)" "unprognostic (8.24e-2)" "unprognostic (2.69e-2)" "unprognostic (2.89e-1)" "unprognostic (2.46e-1)" "unprognostic (1.75e-2)" "unprognostic (3.01e-1)" "unprognostic (1.22e-2)" "unprognostic (2.06e-1)" "unprognostic (7.04e-2)" "unprognostic (4.11e-2)" "unprognostic (2.69e-2)" "unprognostic (5.53e-2)" CYSLTR2 "CysLT(2), CYSLT2R" ENSG00000152207 "Cysteinyl leukotriene receptor 2" Q9NS75 13 48653711-48711226 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 21.6;seminal vesicle: 14.9" "Cell type enhanced" "Detected in many" "cDC: 41.7;Ependymal cells: 26.8;Fallopian secretory cells: 17.8;Granulosa cells: 31.6;Macrophages: 26.4;Melanocytes: 83.6;monocytes: 22.9;NK-cells: 22.4;Pericytes: 48.6;Pituicytes/FSCs: 44.7;Renal collecting duct principal cells: 29.8;Thymocytes: 18.6" "Cell type enriched" "Detected in some" 17 "pericyte: 426.1" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 20.2;Thyroid Carcinoma (TCGA): 15.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 12 "eosinophil: 89.7" "Lineage enriched" "Detected in many" 14 "granulocytes: 89.7" "Cancer enhanced" "Detected in some" "Leukemia: 3.6;lymphoma: 3.1;Neuroblastoma: 2.9" "Adrenal gland - Adrenal cortex cells" HPA046528 Approved NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 6 "HPA046528: " "unprognostic (1.55e-1)" "unprognostic (8.69e-2)" "unprognostic (3.77e-2)" "unprognostic (7.07e-2)" "unprognostic (4.21e-1)" "unprognostic (6.41e-2)" "unprognostic (1.85e-1)" "unprognostic (1.04e-2)" "unprognostic (1.41e-2)" "unprognostic (2.14e-1)" "unprognostic (3.08e-1)" "unprognostic (3.30e-1)" "unprognostic (1.12e-1)" "unprognostic (1.48e-1)" "unprognostic (5.22e-2)" "unprognostic (8.68e-2)" CYSRT1 "C9orf169, MGC59937" ENSG00000197191 "Cysteine rich tail 1" A8MQ03 9 137225174-137226315 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "esophagus: 460.4" "Cell type enriched" "Detected in some" 13 "Esophageal apical cells: 18747.8" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in all" "Head and Neck Squamous Cell Carcinoma (TCGA): 61.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.0" "Lineage enriched" "Detected in single" 6 "monocytes: 1.0" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA021883, HPA021886" Approved Approved "Nuclear speckles,Vesicles,Midbody" Yes No "Cluster 40: Monocytes - Innate immune response" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 84: Apical squamous epithelium - Cornification" 398 "Nuclear speckles" "Vesicles, Midbody" "HPA021883: , HPA021886: " "unprognostic (2.04e-1)" "unprognostic (8.58e-2)" "unprognostic (2.99e-2)" "unprognostic (2.17e-2)" "unprognostic (8.36e-2)" "unprognostic (1.20e-1)" "unprognostic (5.79e-2)" "unprognostic (1.73e-2)" "unprognostic (2.19e-2)" "unprognostic (1.66e-2)" "unprognostic (4.93e-2)" "unprognostic (1.76e-3)" "unprognostic (1.52e-1)" "unprognostic (5.14e-2)" "unprognostic (3.63e-1)" "unprognostic (1.28e-1)" "unprognostic (2.17e-1)" "unprognostic (2.03e-1)" "unprognostic (1.30e-3)" "unprognostic (5.64e-1)" "unprognostic (1.22e-1)" "unprognostic (1.28e-1)" "unprognostic (2.29e-1)" "unprognostic (8.59e-2)" "unprognostic (9.49e-2)" "unprognostic (2.33e-1)" "unprognostic (2.65e-1)" "unprognostic (3.12e-2)" CYSTM1 "C5orf32, ORF1-FL49" ENSG00000120306 "Cysteine rich transmembrane module containing 1" Q9H1C7 5 140175156-140282052 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "stomach 1: 1242.2" "Cell type enhanced" "Detected in all" "Foveolar cells: 2979.7;Gastric chief cells: 3255.4;Late spermatids: 2584.8;Mucous neck cells: 1923.7;Neutrophils: 2229.8;Parietal cells: 5545.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 7 "neutrophil: 427.5" "Lineage enriched" "Detected in all" 7 "granulocytes: 427.5" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Minor Salivary Gland - Endothelial cells, Stomach - Gastric mucous cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050930 Enhanced NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 76: Non-specific - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 97: Non-specific - Cellular respiration" 5 "HPA050930: " "unprognostic (2.00e-2)" "unprognostic (1.16e-1)" "unprognostic (1.56e-1)" "unprognostic (8.98e-2)" "unprognostic (8.48e-2)" "unprognostic (1.32e-2)" "unprognostic (2.16e-2)" "unprognostic (2.02e-3)" "unprognostic (3.15e-1)" "unprognostic (1.74e-3)" "unprognostic (1.17e-1)" "unprognostic (1.34e-2)" "potential prognostic unfavorable (2.88e-4)" "unprognostic (4.00e-1)" "unprognostic (1.77e-1)" "unprognostic (9.43e-2)" "unprognostic (1.28e-1)" "unprognostic (2.04e-1)" "unprognostic (3.95e-2)" "unprognostic (1.89e-1)" "unprognostic (1.53e-3)" "unprognostic (1.90e-1)" "unprognostic (1.99e-1)" "unprognostic (2.54e-2)" "unprognostic (2.88e-1)" "unprognostic (1.85e-1)" "unprognostic (1.49e-1)" "unprognostic (2.93e-1)" "unprognostic (5.78e-2)" CYTH1 "B2-1, cytohesin-1, D17S811E, PSCD1" ENSG00000108669 "Cytohesin 1" Q15438 17 78674048-78782297 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 556.9;monocytes: 697.7;Neutrophils: 872.4" "Cell type enhanced" "Detected in all" "leukocyte: 589.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 5: Spleen - Immune response" "Cluster 11: White matter - Signal transduction" "Cluster 55: Lymphoma - Immune response" "Cluster 82: Dendritic cells - Antigen presentation" 29 "unprognostic (1.44e-1)" "unprognostic (1.46e-2)" "unprognostic (3.15e-3)" "unprognostic (7.49e-2)" "unprognostic (2.36e-1)" "unprognostic (1.05e-1)" "unprognostic (6.38e-3)" "unprognostic (1.98e-3)" "potential prognostic favorable (7.57e-4)" "unprognostic (2.80e-2)" "unprognostic (3.71e-3)" "unprognostic (1.56e-3)" "unprognostic (7.77e-2)" "unprognostic (1.03e-2)" "unprognostic (2.39e-2)" "unprognostic (8.30e-2)" "unprognostic (6.21e-2)" "unprognostic (1.33e-2)" "unprognostic (8.11e-3)" "unprognostic (1.14e-1)" "unprognostic (2.87e-3)" "unprognostic (1.83e-1)" "unprognostic (1.78e-2)" "unprognostic (2.11e-1)" "unprognostic (4.40e-2)" "unprognostic (5.78e-2)" "unprognostic (2.13e-1)" "unprognostic (1.72e-1)" "unprognostic (1.18e-1)" "unprognostic (9.03e-2)" "unprognostic (3.06e-1)" CYTH2 "ARNO, CTS18.1, cytohesin-2, PSCD2, PSCD2L, Sec7p-L, Sec7p-like" ENSG00000105443 "Cytohesin 2" Q99418 19 48469208-48482314 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 363.6;Esophageal apical cells: 324.1;Late primary spermatocytes: 179.1;Late spermatids: 233.2;Syncytiotrophoblasts: 175.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB014872, HPA060662" Uncertain Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 47: Testis - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 56: Non-specific - Sensory perception" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 23 Cytosol "Golgi apparatus, Plasma membrane" "CAB014872: , HPA060662: " "unprognostic (1.04e-2)" "unprognostic (5.06e-2)" "unprognostic (1.84e-1)" "unprognostic (1.85e-1)" "unprognostic (4.64e-2)" "unprognostic (6.07e-2)" "unprognostic (1.42e-1)" "unprognostic (2.26e-2)" "unprognostic (3.62e-1)" "unprognostic (5.77e-2)" "potential prognostic unfavorable (2.05e-4)" "unprognostic (1.42e-1)" "unprognostic (2.18e-3)" "potential prognostic unfavorable (3.64e-4)" "unprognostic (1.25e-1)" "unprognostic (1.88e-2)" "unprognostic (1.74e-1)" "unprognostic (8.16e-2)" "unprognostic (4.05e-2)" "unprognostic (1.50e-1)" "unprognostic (3.16e-1)" "unprognostic (1.06e-1)" "unprognostic (6.39e-2)" "unprognostic (1.48e-3)" "unprognostic (2.23e-1)" "unprognostic (3.54e-1)" "unprognostic (8.42e-2)" "unprognostic (3.52e-1)" "unprognostic (3.87e-2)" "unprognostic (8.84e-2)" "unprognostic (8.60e-2)" CYTH3 "ARNO3, cytohesin-3, GRP1, PSCD3" ENSG00000008256 "Cytohesin 3" O43739 7 6161776-6272644 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Mast cells: 263.2;Melanocytes: 575.7;Pericytes: 213.0" "Cell type enhanced" "Detected in all" "pericyte: 612.3" "Cancer enriched" "Detected in all" 5 "Skin Cutaneous Melanoma (TCGA): 92.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 2.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013979 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 53: Neurons - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 61: Schwann cells & Melanocytes - Mixed function" 10 Cytosol Nucleoplasm "HPA013979: " "unprognostic (3.02e-1)" "unprognostic (3.45e-2)" "unprognostic (1.88e-1)" "unprognostic (2.58e-2)" "unprognostic (4.24e-2)" "unprognostic (2.63e-2)" "unprognostic (5.50e-2)" "unprognostic (3.24e-2)" "unprognostic (3.10e-2)" "potential prognostic unfavorable (2.41e-4)" "unprognostic (2.97e-3)" "potential prognostic favorable (6.32e-4)" "unprognostic (1.70e-1)" "unprognostic (2.59e-2)" "unprognostic (2.61e-1)" "unprognostic (1.14e-1)" "unprognostic (1.62e-2)" "unprognostic (1.19e-1)" "unprognostic (1.96e-1)" "unprognostic (1.11e-2)" "potential prognostic unfavorable (1.62e-5)" "unprognostic (3.72e-1)" "unprognostic (4.47e-1)" "unprognostic (1.83e-1)" "unprognostic (2.52e-1)" "unprognostic (6.72e-3)" "unprognostic (2.35e-2)" "unprognostic (7.82e-3)" "unprognostic (3.74e-1)" "unprognostic (1.75e-2)" "unprognostic (3.70e-3)" CYTH4 "CYT4, cytohesin-4, PSCD4" ENSG00000100055 "Cytohesin 4" Q9UIA0 22 37282027-37315341 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 55.0;lymphoid tissue: 63.5" "Cell type enhanced" "Detected in some" "cDC: 94.7;Hofbauer cells: 144.4;Kupffer cells: 85.1;Macrophages: 102.3;Mast cells: 54.4;Microglia: 116.3;monocytes: 86.0;Neutrophils: 336.9;NK-cells: 50.7;pDCs: 165.9;Plasma cells: 42.7;T-cells: 44.2" "Group enriched" "Detected in some" 70 "central nervous system macrophage: 144.5;leukocyte: 75.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 13 "Leukemia: 24.3;lymphoma: 25.1;Myeloma: 12.2" "Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Skeletal muscle - Macrophages, Spleen - Neutrophils_2, Testis - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004065, HPA071573" Approved Supported "Plasma membrane,Cytokinetic bridge,Centriolar satellite,Cytosol" Yes NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 24: Neutrophils - Innate immunity signal integration" 21 "Plasma membrane" "Cytokinetic bridge, Centriolar satellite, Cytosol" "HPA004065: , HPA071573: " "unprognostic (1.26e-2)" "unprognostic (2.20e-2)" "unprognostic (3.74e-3)" "unprognostic (8.09e-2)" "unprognostic (8.00e-2)" "unprognostic (8.95e-2)" "unprognostic (1.33e-2)" "unprognostic (1.33e-1)" "unprognostic (1.17e-2)" "unprognostic (2.13e-1)" "unprognostic (4.69e-2)" "unprognostic (2.47e-1)" "unprognostic (3.48e-1)" "unprognostic (3.33e-2)" "unprognostic (8.04e-2)" "unprognostic (8.39e-3)" "unprognostic (2.01e-1)" "unprognostic (1.45e-2)" "unprognostic (2.45e-1)" "unprognostic (3.22e-2)" "unprognostic (2.80e-1)" "unprognostic (3.11e-2)" "potential prognostic unfavorable (8.15e-5)" "unprognostic (2.29e-1)" "unprognostic (1.96e-2)" "unprognostic (8.07e-2)" "unprognostic (4.44e-3)" "unprognostic (1.64e-1)" "unprognostic (2.30e-2)" "unprognostic (2.09e-2)" "unprognostic (4.03e-2)" CYTIP "B3-1, CASP, CYBR, CYTHIP, HE, PSCDBP" ENSG00000115165 "Cytohesin 1 interacting protein" O60759 2 157414619-157488961 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 99.7;lymphoid tissue: 107.1" "Cell type enhanced" "Detected in many" "B-cells: 394.7;Breast lactating cells: 657.5;cDC: 492.5;Innate lymphoid cells: 267.7;monocytes: 353.9;Neutrophils: 1793.3;NK-cells: 459.5;Plasma cells: 515.3;T-cells: 578.5" "Cell type enriched" "Detected in some" 8 "leukocyte: 464.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 7 "lymphoma: 87.8;Myeloma: 106.5" "Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Minor Salivary Gland - Plasma cells, Prostate - T-cells, Skin - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA007191 Approved Supported Nucleoplasm,Cytosol No NA "Cluster 35: Neutrophils - Protein binding" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 9 Cytosol Nucleoplasm "HPA007191: " "unprognostic (3.98e-2)" "unprognostic (1.01e-3)" "unprognostic (5.22e-3)" "unprognostic (1.32e-3)" "unprognostic (1.21e-1)" "unprognostic (9.59e-2)" "unprognostic (2.69e-3)" "unprognostic (1.17e-2)" "unprognostic (2.30e-3)" "unprognostic (1.05e-1)" "unprognostic (6.26e-2)" "unprognostic (1.04e-1)" "unprognostic (2.26e-2)" "unprognostic (1.14e-1)" "unprognostic (1.39e-1)" "unprognostic (4.74e-3)" "unprognostic (1.46e-1)" "unprognostic (4.34e-2)" "unprognostic (2.10e-1)" "unprognostic (8.44e-2)" "unprognostic (7.91e-2)" "unprognostic (3.39e-2)" "unprognostic (5.10e-2)" "unprognostic (2.37e-1)" "unprognostic (6.91e-2)" "unprognostic (5.31e-2)" "unprognostic (7.68e-3)" "unprognostic (2.70e-1)" "unprognostic (4.76e-2)" "unprognostic (1.91e-1)" "unprognostic (4.65e-2)" CYTL1 "C17, C4orf4" ENSG00000170891 "Cytokine like 1" Q9NRR1 4 5014586-5019458 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "blood vessel: 198.0" "Cell type enhanced" "Detected in some" "Erythrocyte progenitors: 115.1;Hematopoietic stem cells: 93.2;Hofbauer cells: 27.3;Megakaryocyte progenitors: 49.1;Megakaryocyte-Erythroid progenitors: 271.3;Microglia: 77.7;Retinal pigment epithelial cells: 25.6;Vascular endothelial cells: 31.1" "Group enriched" "Detected in some" 26 "central nervous system macrophage: 102.6;fibroblast: 139.8" "Group enriched" "Detected in many" 4 "Glioblastoma Multiforme (TCGA): 40.6;Skin Cutaneous Melanoma (TCGA): 38.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 10 "NK-cell: 27.1" "Lineage enriched" "Detected in many" 10 "NK-cells: 27.1" "Cancer enhanced" "Detected in many" "Leukemia: 57.1;Sarcoma: 45.1;thyroid cancer: 41.4" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067201 Approved "Nuclear membrane,Endoplasmic reticulum" "Secreted in other tissues" "No annotated function" NA NA 220000 "Cluster 15: NK-cells - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "Nuclear membrane, Endoplasmic reticulum" "HPA067201: " "unprognostic (3.10e-1)" "unprognostic (2.22e-2)" "unprognostic (7.73e-2)" "unprognostic (7.91e-2)" "unprognostic (4.77e-2)" "unprognostic (6.30e-2)" "unprognostic (6.79e-2)" "unprognostic (2.05e-1)" "unprognostic (3.28e-1)" "unprognostic (3.11e-1)" "unprognostic (1.59e-1)" "unprognostic (1.22e-1)" "unprognostic (5.64e-2)" "unprognostic (4.32e-3)" "unprognostic (5.90e-2)" "unprognostic (1.81e-1)" "unprognostic (1.60e-1)" "unprognostic (3.68e-3)" "unprognostic (3.52e-2)" "unprognostic (1.72e-1)" "unprognostic (9.41e-2)" "unprognostic (4.34e-3)" "potential prognostic unfavorable (6.99e-5)" "unprognostic (2.40e-1)" "unprognostic (8.08e-3)" "unprognostic (1.66e-2)" CYYR1 C21orf95 ENSG00000166265 "Cysteine and tyrosine rich 1" Q96J86 21 26466209-26573286 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 333.0;Breast secretory cells: 60.1;Hematopoietic stem cells: 71.3;Lymphatic endothelial cells: 66.3;Medullary thymic epithelial cells: 129.6;Neutrophil progenitors: 138.4;pDCs: 88.7;Vascular endothelial cells: 420.8" "Cell type enriched" "Detected in many" 13 "endothelial cell: 451.9" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 28.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 38 "plasmacytoid DC: 31.5" "Lineage enriched" "Detected in single" 82 "dendritic cells: 31.5" "Cancer enhanced" "Detected in some" "Bone cancer: 14.6" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Pancreas - Endothelial cells, Pituitary gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Spleen - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034921, HPA067685" Uncertain Approved Nucleoplasm NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" Nucleoplasm "CAB034921: , HPA067685: " "unprognostic (7.15e-3)" "unprognostic (1.25e-1)" "unprognostic (2.17e-1)" "unprognostic (5.56e-2)" "unprognostic (1.85e-2)" "unprognostic (1.10e-2)" "unprognostic (7.62e-2)" "unprognostic (6.91e-3)" "unprognostic (4.52e-2)" "unprognostic (1.51e-3)" "validated prognostic favorable (2.73e-11)" "validated prognostic favorable (1.22e-4)" "unprognostic (6.85e-3)" "unprognostic (1.33e-3)" "unprognostic (2.91e-3)" "unprognostic (4.14e-2)" "unprognostic (1.87e-1)" "unprognostic (3.48e-2)" "unprognostic (5.09e-1)" "unprognostic (1.84e-1)" "unprognostic (2.36e-2)" "unprognostic (3.88e-2)" "unprognostic (4.02e-2)" "unprognostic (8.99e-2)" "unprognostic (1.40e-2)" "unprognostic (2.38e-1)" "unprognostic (6.70e-3)" "unprognostic (1.80e-2)" "unprognostic (2.52e-1)" "unprognostic (2.04e-1)" "unprognostic (1.46e-1)" CZIB "C1orf123, FLJ20580" ENSG00000162384 "CXXC motif containing zinc binding protein" Q9NWV4 1 53214099-53220634 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Decidual stromal cells: 167.1;Late primary spermatocytes: 167.3;Late spermatids: 390.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043835 Uncertain Approved "Vesicles,Mitotic spindle,Cytosol" Yes No 690000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 37: Non-specific - mRNA processing" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 1 Cytosol "Vesicles, Mitotic spindle" "HPA043835: " "unprognostic (1.56e-2)" "unprognostic (2.87e-1)" "unprognostic (1.92e-1)" "unprognostic (1.50e-1)" "unprognostic (7.51e-2)" "unprognostic (3.08e-1)" "unprognostic (1.59e-3)" "unprognostic (1.73e-3)" "unprognostic (1.93e-1)" "potential prognostic favorable (6.72e-4)" "unprognostic (5.75e-3)" "unprognostic (1.16e-1)" "unprognostic (3.47e-3)" "unprognostic (8.71e-2)" "unprognostic (6.12e-2)" "unprognostic (1.41e-2)" "unprognostic (2.00e-2)" "unprognostic (6.40e-2)" "unprognostic (1.32e-1)" "unprognostic (2.09e-2)" "unprognostic (2.14e-1)" "unprognostic (2.43e-1)" "unprognostic (7.21e-2)" "unprognostic (1.49e-1)" "unprognostic (6.94e-2)" "unprognostic (4.64e-3)" "unprognostic (2.69e-1)" "unprognostic (1.85e-1)" "unprognostic (2.55e-1)" D2HGDH "D2HGD, FLJ42195, MGC25181" ENSG00000180902 "D-2-hydroxyglutarate dehydrogenase" Q8N465 2 241734602-241768816 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubule cells: 180.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 2.5" "Group enriched" "Detected in many" 4 "B-cells: 2.5;T-cells: 1.0" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056216, HPA060548" Uncertain Supported Mitochondria NA NA "Cluster 24: Non-specific - Transcription" "Cluster 76: Non-specific - Metabolism" "Cluster 36: Choroid plexus - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 88: Proximal tubular cells - Transmembrane transport" 70 Mitochondria "HPA056216: , HPA060548: " "unprognostic (3.13e-1)" "unprognostic (9.72e-2)" "unprognostic (3.17e-2)" "unprognostic (3.03e-2)" "unprognostic (2.48e-1)" "unprognostic (1.33e-1)" "unprognostic (5.89e-2)" "unprognostic (1.72e-1)" "unprognostic (8.98e-3)" "unprognostic (3.08e-2)" "potential prognostic favorable (7.31e-5)" "unprognostic (9.82e-3)" "unprognostic (1.30e-2)" "unprognostic (3.48e-1)" "unprognostic (3.78e-3)" "unprognostic (4.55e-2)" "unprognostic (1.03e-1)" "unprognostic (2.80e-1)" "unprognostic (1.12e-2)" "unprognostic (3.48e-2)" "unprognostic (7.99e-2)" "unprognostic (2.26e-1)" "unprognostic (4.78e-2)" "unprognostic (6.32e-2)" "unprognostic (2.55e-2)" "unprognostic (2.37e-1)" "unprognostic (1.13e-2)" "unprognostic (3.08e-2)" "unprognostic (6.23e-2)" "unprognostic (3.49e-1)" "unprognostic (2.13e-2)" DAAM1 KIAA0666 ENSG00000100592 "Dishevelled associated activator of morphogenesis 1" Q9Y4D1 14 59188646-59371405 "Plasma proteins, Predicted intracellular proteins" "Wnt signaling pathway" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 786.0;Retinal pigment epithelial cells: 1155.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Skin - Keratinocyte (other), Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026605, HPA064789" Uncertain Approved "Plasma membrane,Cytosol" NA NA 5200 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 58: Skin - Keratinization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" 13 Cytosol "Plasma membrane" "HPA026605: , HPA064789: " "unprognostic (1.61e-1)" "unprognostic (3.00e-1)" "unprognostic (2.99e-1)" "unprognostic (6.62e-2)" "unprognostic (5.01e-2)" "unprognostic (1.37e-1)" "unprognostic (2.31e-1)" "unprognostic (3.63e-1)" "unprognostic (2.21e-1)" "potential prognostic unfavorable (9.07e-5)" "potential prognostic favorable (4.66e-5)" "unprognostic (1.18e-3)" "unprognostic (1.31e-1)" "unprognostic (7.94e-2)" "unprognostic (2.37e-1)" "unprognostic (1.33e-1)" "unprognostic (3.28e-1)" "unprognostic (3.74e-1)" "unprognostic (2.43e-1)" "unprognostic (8.51e-2)" "unprognostic (1.73e-3)" "unprognostic (1.35e-1)" "unprognostic (1.53e-2)" "unprognostic (6.95e-2)" "unprognostic (9.24e-2)" "unprognostic (2.35e-1)" "unprognostic (2.84e-1)" "unprognostic (5.04e-2)" "unprognostic (1.51e-1)" "unprognostic (4.55e-2)" "unprognostic (1.37e-1)" DAAM2 "KIAA0381, NPHS24" ENSG00000146122 "Dishevelled associated activator of morphogenesis 2" Q86T65 6 39792298-39904877 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Wnt signaling pathway" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 145.9" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 286.1;Astrocytes: 482.1;Kupffer cells: 198.8;Neutrophil progenitors: 165.4;Neutrophils: 600.2;Oligodendrocytes: 563.4;Pericytes: 266.1;Vascular smooth muscle cells: 156.5" "Group enriched" "Detected in many" 4 "astrocyte: 787.1;committed oligodendrocyte precursor: 273.6;oligodendrocyte: 719.8;pericyte: 567.6;vascular associated smooth muscle cell: 290.7" "Group enriched" "Detected in all" 4 "Glioblastoma Multiforme (TCGA): 35.5;Skin Cutaneous Melanoma (TCGA): 57.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "skin cancer: 66.7" "Kidney - Fibroblasts, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051300, HPA054630" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 24: Neutrophils - Innate immunity signal integration" Nucleoplasm "Vesicles, Cytosol" "HPA051300: , HPA054630: " "unprognostic (6.15e-2)" "unprognostic (1.16e-2)" "unprognostic (3.17e-1)" "unprognostic (3.30e-3)" "unprognostic (9.94e-2)" "unprognostic (2.32e-1)" "unprognostic (8.81e-2)" "unprognostic (4.64e-3)" "unprognostic (5.68e-2)" "unprognostic (1.21e-1)" "unprognostic (1.23e-3)" "potential prognostic favorable (7.78e-4)" "unprognostic (2.27e-3)" "unprognostic (9.42e-2)" "unprognostic (7.54e-3)" "potential prognostic favorable (2.95e-6)" "unprognostic (6.09e-2)" "unprognostic (6.85e-2)" "unprognostic (3.76e-1)" "unprognostic (2.08e-2)" "unprognostic (2.02e-3)" "unprognostic (2.08e-1)" "unprognostic (3.36e-1)" "unprognostic (1.37e-2)" "unprognostic (6.52e-2)" "unprognostic (3.84e-2)" "unprognostic (5.91e-2)" "unprognostic (3.96e-2)" "unprognostic (8.95e-2)" "unprognostic (1.29e-1)" "unprognostic (1.41e-1)" DAB1 ENSG00000173406 "DAB adaptor protein 1" O75553 1 56994778-58546734 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 15.2;intestine: 21.1;seminal vesicle: 9.4" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 1264.6;Brain inhibitory neurons: 682.3;Enterocytes: 640.7;Oligodendrocyte progenitor cells: 1218.2;Other brain neurons: 668.1;Retinal amacrine cells: 589.4;Retinal bipolar cells: 968.1;Retinal horizontal cells: 1240.1;Thyrotrophs: 431.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "MAIT T-cell: 2.1" "Lineage enhanced" "Detected in single" "T-cells: 2.1" "Cancer enriched" "Detected in some" 4 "Bone cancer: 20.5" "Adipose subcutaneous - Smooth muscle cells, Colon - Enteric glia cells, Skin - Outer root sheath cells, Stomach - Fibroblasts, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032329, HPA052033, HPA067495" Enhanced Enhanced Vesicles NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 77: Intestine - Digestion" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" 52 Vesicles "CAB032329: , HPA052033: , HPA067495: " "unprognostic (3.63e-2)" "unprognostic (1.32e-1)" "unprognostic (2.72e-1)" "unprognostic (2.49e-1)" "unprognostic (2.68e-1)" "unprognostic (5.85e-3)" "potential prognostic favorable (4.91e-5)" "unprognostic (3.54e-1)" "unprognostic (4.24e-1)" "unprognostic (1.52e-3)" "unprognostic (1.72e-1)" "unprognostic (1.05e-2)" DAB2 DOC-2 ENSG00000153071 "DAB adaptor protein 2" P98082 5 39371675-39462300 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Differentiation, Endocytosis, Protein transport, Transport, Wnt signaling pathway" "Developmental protein" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 167.4;placenta: 213.0" "Cell type enhanced" "Detected in many" "Breast lactating cells: 199.5;Epididymal efferent duct absorptive cells: 453.0;Epididymal principal cells: 305.0;Hofbauer cells: 1695.9;Platelets: 847.3;Syncytiotrophoblasts: 941.8" "Cell type enhanced" "Detected in many" "Bergmann glia: 32.9;endothelial cell: 19.4;fibroblast: 19.5" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 177.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 8 "plasmacytoid DC: 48.8" "Lineage enriched" "Detected in many" 8 "dendritic cells: 48.8" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009314, HPA028888" Enhanced Enhanced "Nucleoli fibrillar center,Vesicles,Plasma membrane" NA NA 53000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 33 "Vesicles, Plasma membrane" "Nucleoli fibrillar center" "CAB009314: , HPA028888: " "unprognostic (5.29e-2)" "unprognostic (1.85e-1)" "unprognostic (8.24e-2)" "unprognostic (2.36e-2)" "unprognostic (4.38e-1)" "unprognostic (1.37e-1)" "unprognostic (4.15e-3)" "unprognostic (1.60e-1)" "unprognostic (5.95e-2)" "unprognostic (3.28e-3)" "potential prognostic favorable (4.08e-7)" "unprognostic (8.64e-3)" "unprognostic (4.01e-2)" "potential prognostic unfavorable (3.80e-7)" "unprognostic (1.69e-1)" "unprognostic (1.55e-1)" "potential prognostic unfavorable (3.84e-4)" "unprognostic (5.20e-2)" "unprognostic (1.32e-2)" "unprognostic (5.60e-3)" "unprognostic (7.29e-3)" "unprognostic (1.03e-1)" "unprognostic (5.94e-2)" "unprognostic (2.06e-1)" "unprognostic (4.86e-2)" "unprognostic (1.44e-3)" "unprognostic (9.04e-2)" "potential prognostic unfavorable (3.90e-4)" "unprognostic (1.34e-2)" "unprognostic (2.92e-2)" "unprognostic (1.07e-1)" DAB2IP "AF9Q34, AIP1, DIP1/2, KIAA1743" ENSG00000136848 "DAB2 interacting protein" Q5VWQ8 9 121567057-121785530 "Disease related genes, Predicted intracellular proteins" "Angiogenesis, Apoptosis, Cell cycle, Growth regulation, Immunity, Inflammatory response, Innate immunity, Stress response, Unfolded protein response" "Developmental protein, GTPase activation" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 144.8" "Cell type enhanced" "Detected in many" "Müller glia: 254.1;Myonuclei: 333.5;Syncytiotrophoblasts: 174.8" "Cell type enhanced" "Detected in all" "endothelial cell: 197.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 16 "unprognostic (6.69e-2)" "unprognostic (5.88e-2)" "unprognostic (1.03e-1)" "unprognostic (5.03e-2)" "unprognostic (4.35e-2)" "unprognostic (4.31e-2)" "unprognostic (7.39e-2)" "potential prognostic favorable (9.83e-4)" "unprognostic (2.38e-1)" "unprognostic (1.62e-1)" "validated prognostic favorable (1.12e-10)" "validated prognostic favorable (4.53e-4)" "potential prognostic favorable (3.19e-5)" "unprognostic (3.59e-1)" "unprognostic (7.03e-2)" "unprognostic (4.56e-2)" "unprognostic (4.93e-2)" "unprognostic (3.13e-3)" "unprognostic (2.83e-1)" "unprognostic (1.44e-2)" "unprognostic (1.45e-1)" "unprognostic (1.27e-1)" "unprognostic (2.07e-1)" "unprognostic (5.75e-2)" "unprognostic (5.44e-2)" "unprognostic (1.08e-1)" "unprognostic (1.44e-2)" "unprognostic (4.97e-2)" "unprognostic (4.53e-1)" "unprognostic (5.29e-2)" "unprognostic (2.00e-1)" DACH1 DACH ENSG00000276644 "Dachshund family transcription factor 1" Q9UI36 13 71437966-71867204 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 19.3" "Cell type enhanced" "Detected in many" "Corticotrophs: 849.9;Distal convoluted tubule cells: 1034.1;Gonadotrophs: 783.7;Müller glia: 1078.8;Neutrophil progenitors: 1979.1;Neutrophils: 955.5;Paneth cells: 858.6;Podocytes: 5507.1;Renal connecting tubule cells: 750.7;Retinal horizontal cells: 753.3" "Cell type enhanced" "Detected in all" "endothelial cell: 827.9;medium spiny neuron: 810.4;pericyte: 1190.8" "Cancer enhanced" "Detected in many" "Rectum Adenocarcinoma (TCGA): 15.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "basophil: 6.0;eosinophil: 11.3;NK-cell: 5.7;plasmacytoid DC: 9.3" "Group enriched" "Detected in many" 29 "dendritic cells: 9.3;granulocytes: 11.3;NK-cells: 5.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 10.4" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Adrenal gland - Adrenal cortex cells, Liver - Hepatic stellate cells, Pituitary gland - Thyrotropes, Skin - Outer root sheath cells, Spleen - Endothelial cells, Testis - Early spermatids" "Region enriched" "Detected in all" 5 "basal ganglia: 38.8" "Region enriched" "Detected in all" 6 "basal ganglia: 45.2" "HPA012672, HPA012938, HPA073222" Approved Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 42: Retina - Visual perception" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 57: Podocytes - Glomerular filtration" 12 "Nucleoplasm, Nuclear speckles" "HPA012672: , HPA012938: , HPA073222: " "unprognostic (1.31e-1)" "unprognostic (2.38e-1)" "unprognostic (4.50e-2)" "unprognostic (8.11e-2)" "unprognostic (2.45e-1)" "unprognostic (4.54e-2)" "unprognostic (2.61e-2)" "unprognostic (1.26e-1)" "validated prognostic favorable (2.89e-4)" "validated prognostic favorable (6.01e-4)" "unprognostic (9.68e-2)" "unprognostic (1.27e-2)" "unprognostic (1.96e-1)" "unprognostic (2.19e-1)" "unprognostic (2.11e-2)" "unprognostic (1.06e-1)" "potential prognostic favorable (4.13e-4)" "unprognostic (3.40e-1)" "unprognostic (2.22e-1)" "unprognostic (2.87e-3)" "unprognostic (1.02e-1)" "unprognostic (1.22e-1)" "unprognostic (3.46e-3)" DACH2 ENSG00000126733 "Dachshund family transcription factor 2" Q96NX9 X 86148451-86832604 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.4;epididymis: 3.5;fallopian tube: 3.6" "Group enriched" "Detected in many" 4 "Corticotrophs: 636.5;Podocytes: 847.1" "Cell type enhanced" "Detected in all" "vascular associated smooth muscle cell: 191.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 1.4;Neuroblastoma: 1.0" "Colon - Colon enteroendocrine cells, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Beta cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA000258, HPA001367" Approved Approved Nucleoplasm NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 11: Neuronal - Sensory perception" "Cluster 57: Podocytes - Glomerular filtration" Nucleoplasm "HPA000258: , HPA001367: " "potential prognostic favorable (6.13e-4)" DACT1 "DAPPER, DAPPER1, FRODO, HDPR1, THYEX3" ENSG00000165617 "Dishevelled binding antagonist of beta catenin 1" Q9NYF0 14 58633967-58648321 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Neurogenesis, Wnt signaling pathway" "Developmental protein" "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 36.1" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 3.6;Endometrial stromal cells: 4.0;Fibroblasts: 5.1;Gonadotrophs: 5.8;Microglia: 3.2;Ovarian stromal cells: 4.1;Paneth cells: 3.9;Pericytes: 4.3;Salivary myoepithelial cells: 4.2;Schwann cells: 3.7;Undifferentiated spermatogonia: 2.7;Vascular smooth muscle cells: 4.0" "Cell type enhanced" "Detected in many" "fibroblast: 12.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003016, HPA074619" Enhanced Supported Nucleoplasm NA NA "Cluster 75: Ovary - Mixed function" "Cluster 35: Non-specific - DNA binding" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 103: Non-specific - Basic cellular processes" 8 Nucleoplasm "HPA003016: , HPA074619: " "unprognostic (3.56e-3)" "unprognostic (6.92e-2)" "unprognostic (4.91e-2)" "unprognostic (8.89e-3)" "unprognostic (2.00e-2)" "unprognostic (1.37e-2)" "unprognostic (1.84e-2)" "unprognostic (2.30e-1)" "unprognostic (4.26e-3)" "unprognostic (2.75e-1)" "unprognostic (2.09e-1)" "unprognostic (1.74e-2)" "unprognostic (1.64e-1)" "unprognostic (2.65e-2)" "unprognostic (2.96e-3)" "unprognostic (2.03e-1)" "unprognostic (1.71e-2)" "unprognostic (6.89e-3)" "unprognostic (2.77e-1)" "unprognostic (3.17e-2)" "unprognostic (5.96e-3)" "unprognostic (7.41e-2)" "unprognostic (7.29e-2)" "unprognostic (7.86e-2)" "unprognostic (2.95e-2)" "unprognostic (7.81e-2)" "unprognostic (1.40e-1)" "unprognostic (7.69e-3)" "unprognostic (2.56e-1)" "unprognostic (2.31e-3)" "unprognostic (2.28e-1)" DACT2 "bA503C24.7, C6orf116, DAPPER2" ENSG00000164488 "Dishevelled binding antagonist of beta catenin 2" Q5SW24 6 168292830-168319777 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.2;placenta: 12.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 74.2;Endometrial ciliated cells: 18.4;Endometrial luminal cells: 26.6;Migrating cytotrophoblasts: 40.9;Müller glia: 52.8;Retinal bipolar cells: 22.1;Syncytiotrophoblasts: 258.8" "Group enriched" "Detected in many" 4 "cerebellar inhibitory: 11.7;endothelial cell: 38.9;medium spiny neuron: 18.1" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 27.0" "Region enriched" "Detected in many" 5 "basal ganglia: 39.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Adrenocortical cancer: 14.2;Bone cancer: 25.1" "Prostate - Prostate glandular cells, Stomach - Chief cells" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "basal ganglia: 21.1;cerebral cortex: 26.4;hippocampal formation: 21.0" HPA030251 Approved Supported NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" "HPA030251: " "unprognostic (8.01e-2)" "unprognostic (2.33e-1)" "unprognostic (2.84e-2)" "unprognostic (3.32e-1)" "unprognostic (1.40e-1)" "unprognostic (1.33e-1)" "unprognostic (5.78e-2)" "unprognostic (1.26e-1)" "unprognostic (5.77e-3)" "unprognostic (1.99e-3)" "potential prognostic favorable (4.70e-5)" "unprognostic (3.64e-2)" "unprognostic (4.87e-3)" "unprognostic (8.08e-2)" "unprognostic (5.35e-3)" "unprognostic (4.11e-2)" "unprognostic (1.78e-3)" "unprognostic (7.29e-2)" "unprognostic (2.32e-2)" "unprognostic (5.31e-3)" "unprognostic (1.89e-3)" "unprognostic (2.56e-1)" "unprognostic (1.74e-2)" "unprognostic (3.67e-1)" "unprognostic (3.09e-1)" "unprognostic (1.48e-2)" "unprognostic (1.30e-2)" "unprognostic (1.36e-3)" DACT3 "DAPPER3, MGC15476, RRR1" ENSG00000197380 "Dishevelled binding antagonist of beta catenin 3" Q96B18 19 46647551-46661182 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 119.2" "Cell type enhanced" "Detected in many" "Astrocytes: 16.3;Bergmann glia: 27.1;Brain inhibitory neurons: 15.0;Early spermatids: 30.2;Microglia: 17.0;Oligodendrocyte progenitor cells: 24.2;Oligodendrocytes: 39.1;Peritubular myoid cells: 14.7;Retinal amacrine cells: 18.1;Smooth muscle cells: 57.9;Vascular smooth muscle cells: 72.7" "Cell type enhanced" "Detected in all" "vascular associated smooth muscle cell: 86.2" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 24.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.4" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Neuroblastoma: 17.1" "Adipose subcutaneous - Smooth muscle cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043053 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 74: Non-specific - Signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 62: Smooth muscle cells - Muscle contraction" 5 Vesicles Nucleoplasm "HPA043053: " "unprognostic (4.67e-3)" "unprognostic (4.55e-1)" "unprognostic (8.89e-2)" "unprognostic (1.60e-1)" "unprognostic (1.90e-2)" "unprognostic (1.83e-1)" "unprognostic (1.09e-1)" "unprognostic (1.45e-2)" "unprognostic (2.97e-1)" "unprognostic (9.33e-3)" "unprognostic (2.11e-1)" "unprognostic (2.26e-3)" "unprognostic (9.94e-3)" "unprognostic (2.63e-1)" "unprognostic (7.53e-2)" "unprognostic (2.05e-1)" "unprognostic (1.53e-1)" "unprognostic (5.35e-3)" "unprognostic (9.09e-2)" "unprognostic (2.18e-3)" "unprognostic (1.06e-2)" "unprognostic (1.73e-1)" "unprognostic (7.54e-2)" "unprognostic (1.09e-1)" "unprognostic (2.28e-2)" "unprognostic (6.81e-2)" "unprognostic (4.88e-3)" "unprognostic (3.56e-2)" "unprognostic (8.43e-2)" "unprognostic (1.58e-3)" "unprognostic (3.58e-2)" DAD1 OST2 ENSG00000129562 "Defender against cell death 1" P61803 14 22564907-22589224 "Cancer-related genes, Essential proteins, Metabolic proteins, Predicted membrane proteins, Transporters" Apoptosis "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 971.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028882 Uncertain Uncertain "Endoplasmic reticulum,Cytosol" NA NA 11000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 22: Epididymis - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 35: RS4;11 - Unknown function" "Cluster 8: Non-specific - Secretory pathway" 57 Cytosol "Endoplasmic reticulum" "HPA028882: " "unprognostic (6.04e-2)" "unprognostic (2.27e-1)" "unprognostic (5.22e-3)" "unprognostic (4.94e-2)" "unprognostic (1.18e-2)" "unprognostic (2.48e-1)" "unprognostic (3.13e-1)" "unprognostic (4.44e-1)" "potential prognostic unfavorable (3.41e-4)" "unprognostic (1.02e-3)" "potential prognostic favorable (2.63e-5)" "unprognostic (6.86e-2)" "unprognostic (1.82e-1)" "validated prognostic unfavorable (2.49e-4)" "validated prognostic unfavorable (9.21e-4)" "validated prognostic unfavorable (9.11e-4)" "validated prognostic unfavorable (5.07e-4)" "unprognostic (3.01e-1)" "unprognostic (6.41e-2)" "unprognostic (2.91e-1)" "unprognostic (3.47e-1)" "unprognostic (1.34e-2)" "unprognostic (2.89e-1)" "unprognostic (6.65e-2)" "unprognostic (2.24e-1)" "unprognostic (1.66e-2)" "unprognostic (1.07e-1)" "unprognostic (6.81e-2)" "unprognostic (5.11e-2)" "unprognostic (2.82e-1)" "unprognostic (1.08e-2)" DAG1 "156DAG, A3a, AGRNR, DAG" ENSG00000173402 "Dystroglycan 1" Q14118 3 49468713-49535618 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Limb-girdle muscular dystrophy, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 285.5;Myosatellite cells: 229.0;Schwann cells: 221.4;Thymic myoid cells: 186.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Smooth muscle cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001960, CAB016353, HPA070563" Enhanced Supported "Nucleoplasm,Vesicles,Plasma membrane" "Intracellular and membrane" Receptor NA NA 42000000 "Cluster 29: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 39 "Vesicles, Plasma membrane" Nucleoplasm "CAB001960: , CAB016353: , HPA070563: " "unprognostic (8.32e-2)" "unprognostic (1.10e-1)" "unprognostic (7.72e-2)" "unprognostic (2.01e-2)" "unprognostic (2.78e-2)" "unprognostic (1.98e-1)" "unprognostic (2.61e-1)" "unprognostic (2.67e-3)" "unprognostic (1.14e-1)" "unprognostic (5.21e-2)" "unprognostic (1.20e-2)" "unprognostic (1.70e-1)" "unprognostic (8.76e-3)" "unprognostic (1.19e-1)" "unprognostic (6.25e-3)" "unprognostic (4.55e-2)" "unprognostic (4.39e-2)" "unprognostic (8.21e-2)" "unprognostic (1.52e-1)" "unprognostic (5.13e-2)" "unprognostic (5.92e-2)" "unprognostic (6.52e-3)" "potential prognostic favorable (6.76e-6)" "unprognostic (2.62e-1)" "unprognostic (8.35e-2)" "unprognostic (8.33e-2)" "unprognostic (1.26e-1)" "unprognostic (9.82e-2)" "unprognostic (1.75e-1)" "unprognostic (1.47e-2)" "unprognostic (1.66e-1)" DAGLA "C11orf11, DAGLALPHA, KIAA0659, NSDDR" ENSG00000134780 "Diacylglycerol lipase alpha" Q9Y4D2 11 61680391-61747001 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease variant, Intellectual disability, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.3" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Spleen - Macrophages, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062497, CAB078793" Approved Supported NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" 9 "CAB078793: , HPA062497: " "unprognostic (3.64e-1)" "unprognostic (7.14e-2)" "unprognostic (1.96e-1)" "unprognostic (1.22e-1)" "unprognostic (2.19e-1)" "unprognostic (8.64e-2)" "potential prognostic favorable (1.76e-4)" "unprognostic (2.28e-2)" "unprognostic (5.74e-2)" "unprognostic (4.93e-2)" "unprognostic (2.35e-2)" "unprognostic (9.97e-2)" "unprognostic (2.81e-2)" "unprognostic (1.49e-2)" "unprognostic (2.12e-1)" "unprognostic (1.93e-1)" "unprognostic (2.06e-1)" "unprognostic (7.25e-3)" "unprognostic (5.00e-3)" "unprognostic (4.59e-2)" "unprognostic (6.69e-2)" "unprognostic (3.14e-1)" "unprognostic (2.49e-1)" "unprognostic (1.02e-1)" DAGLB "DAGLBETA, KCCR13L" ENSG00000164535 "Diacylglycerol lipase beta" Q8NCG7 7 6409126-6484190 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 71.3;Microglia: 97.6;Neutrophil progenitors: 78.3" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 118.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 88.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069377 Supported "Nucleoplasm,Plasma membrane" No No "Cluster 29: Non-specific - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 2 "Plasma membrane" Nucleoplasm "HPA069377: " "unprognostic (3.75e-1)" "unprognostic (1.27e-2)" "unprognostic (2.33e-1)" "unprognostic (1.39e-2)" "unprognostic (1.62e-1)" "unprognostic (2.36e-1)" "unprognostic (2.06e-2)" "unprognostic (1.05e-1)" "unprognostic (2.89e-2)" "unprognostic (5.54e-3)" "potential prognostic favorable (4.82e-4)" "unprognostic (1.46e-1)" "unprognostic (5.02e-2)" "potential prognostic unfavorable (1.22e-4)" "unprognostic (1.85e-1)" "unprognostic (9.90e-2)" "unprognostic (1.78e-1)" "unprognostic (1.09e-1)" "unprognostic (1.37e-1)" "unprognostic (6.40e-3)" "unprognostic (1.24e-2)" "unprognostic (1.98e-1)" "unprognostic (4.34e-3)" "unprognostic (8.67e-2)" "unprognostic (1.21e-1)" "unprognostic (5.59e-2)" "unprognostic (1.12e-1)" "unprognostic (1.49e-1)" "unprognostic (2.01e-1)" "unprognostic (2.09e-2)" "unprognostic (2.16e-1)" DALRD3 FLJ10496 ENSG00000178149 "DALR anticodon binding domain containing 3" Q5D0E6 3 49015488-49022293 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 149.3;Enterocytes: 172.2;Epicardial cells: 193.3;Fallopian tube ciliated cells: 166.7;Late primary spermatocytes: 243.0;Late spermatids: 452.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036862 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 21: Testis - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 65: Non-specific - Cell growth & division" 1 Nucleoplasm "Nuclear bodies, Cytosol" "HPA036862: " "unprognostic (8.27e-2)" "unprognostic (1.64e-2)" "unprognostic (1.10e-1)" "unprognostic (2.27e-2)" "unprognostic (1.84e-1)" "unprognostic (4.50e-2)" "unprognostic (4.19e-1)" "unprognostic (2.32e-2)" "unprognostic (1.26e-1)" "unprognostic (1.16e-3)" "unprognostic (1.79e-2)" "unprognostic (2.70e-1)" "potential prognostic favorable (8.06e-5)" "unprognostic (2.09e-2)" "unprognostic (1.06e-1)" "unprognostic (5.22e-1)" "unprognostic (1.51e-3)" "unprognostic (4.04e-2)" "unprognostic (2.05e-2)" "unprognostic (1.80e-2)" "unprognostic (1.82e-1)" "unprognostic (4.55e-3)" "unprognostic (3.09e-1)" "unprognostic (2.47e-1)" "unprognostic (1.69e-1)" "unprognostic (2.88e-1)" "unprognostic (6.36e-2)" "unprognostic (3.27e-2)" "unprognostic (2.05e-1)" "unprognostic (7.60e-2)" "unprognostic (1.14e-1)" DAND5 "CER2, CKTSF1B3, Coco, DANTE, DTE, FLJ38607, GREM3" ENSG00000179284 "DAN domain BMP antagonist family member 5" Q8N907 19 12965159-12974760 "Predicted secreted proteins" Heterotaxy "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 4.7;heart muscle: 7.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 37.3;Epididymal basal cells: 11.0;Granulosa cells: 21.1;Oocytes: 4.6;pDCs: 5.2;Smooth muscle cells: 7.8;Thymocytes: 5.9" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 4.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 1.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in some" "Heart muscle - Cardiomyocytes" "Not detected" "Not detected" "HPA043493, HPA049472" Uncertain Approved Mitochondria "Secreted in other tissues" "No annotated function" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 35: Non-specific - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 1: Neuronal - Visual perception" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" Mitochondria "HPA043493: , HPA049472: " "unprognostic (1.48e-1)" "unprognostic (4.67e-2)" "unprognostic (7.76e-3)" "unprognostic (1.59e-3)" "unprognostic (7.05e-3)" "unprognostic (4.44e-2)" "unprognostic (6.22e-3)" DAO "DAAO, DAMOX" ENSG00000110887 "D-amino acid oxidase" P14920 12 108858932-108901043 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 48.2;kidney: 84.2;liver: 139.9" "Group enriched" "Detected in some" 4 "Bergmann glia: 132.8;Hepatocytes: 53.0" "Group enriched" "Detected in many" 17 "astrocyte: 47.9;Bergmann glia: 174.8" "Cancer enriched" "Detected in some" 5 "Liver Hepatocellular Carcinoma (TCGA): 41.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Group enriched" "Detected in some" 10 "cerebellum: 66.4;pons and medulla: 20.2" "Low region specificity" "Detected in many" "HPA038653, HPA038654" Enhanced "Intracellular and membrane" Enzyme NA NA "Cluster 16: Liver & Kidney - Metabolism" "Cluster 25: Non-specific - Transcription" "Cluster 18: Liver cancer - Metabolism" "Cluster 28: Astrocytes - Homeostasis & neuron support" 5 "HPA038653: , HPA038654: " "unprognostic (2.11e-1)" "unprognostic (4.31e-3)" "potential prognostic favorable (1.16e-7)" "unprognostic (1.02e-2)" "unprognostic (2.20e-2)" "unprognostic (1.46e-3)" "potential prognostic favorable (2.61e-4)" DAOA G72 ENSG00000182346 "D-amino acid oxidase activator" P59103 13 105465867-105491034 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Schizophrenia "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA053114 Uncertain NA NA "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 2 "HPA053114: " DAP DAP1 ENSG00000112977 "Death associated protein" P51397 5 10679230-10761234 "Predicted intracellular proteins" "Apoptosis, Autophagy, Translation regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Breast lactating cells: 499.8" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 177.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029456 Uncertain Approved Nucleoplasm,Vesicles,Mitochondria NA NA 36000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 8: Pancreas - Proteolysis" "Cluster 8: Immune cells - Immune response" "Cluster 29: Non-specific - Unknown function" "Cluster 4: Breast lactating luminal cells - Lactation" 3 "Vesicles, Mitochondria" Nucleoplasm "HPA029456: " "unprognostic (1.36e-1)" "unprognostic (5.82e-2)" "unprognostic (1.22e-1)" "unprognostic (2.52e-1)" "unprognostic (1.14e-1)" "unprognostic (1.85e-1)" "unprognostic (1.85e-1)" "unprognostic (1.02e-2)" "unprognostic (1.52e-1)" "unprognostic (3.02e-1)" "potential prognostic favorable (2.68e-5)" "unprognostic (1.17e-1)" "unprognostic (1.90e-1)" "potential prognostic unfavorable (1.63e-6)" "unprognostic (2.27e-3)" "unprognostic (1.97e-1)" "potential prognostic unfavorable (2.26e-4)" "unprognostic (1.25e-1)" "unprognostic (1.31e-1)" "unprognostic (4.11e-2)" "unprognostic (2.08e-1)" "unprognostic (5.60e-2)" "unprognostic (5.58e-2)" "unprognostic (1.44e-1)" "unprognostic (3.27e-1)" "unprognostic (1.92e-2)" "unprognostic (1.02e-1)" "unprognostic (3.33e-1)" "unprognostic (1.48e-1)" "unprognostic (3.05e-1)" "unprognostic (2.41e-1)" DAP3 "bMRP-10, DAP-3, DKFZp686G12159, MGC126058, MGC126059, MRP-S29, MRPS29" ENSG00000132676 "Death associated protein 3" P51398 1 155687960-155739010 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" Apoptosis "Hydrolase, Ribonucleoprotein, Ribosomal protein" "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023687 Approved Enhanced Nucleoplasm,Mitochondria NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 52: Non-specific - Cellular respiration" "Cluster 6: Non-specific - Immune response" "Cluster 45: Non-specific - Nuclear processes" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 96 "Nucleoplasm, Mitochondria" "HPA023687: " "unprognostic (4.05e-1)" "unprognostic (1.45e-1)" "unprognostic (1.27e-1)" "unprognostic (1.63e-2)" "unprognostic (2.05e-1)" "unprognostic (1.72e-1)" "unprognostic (2.57e-1)" "unprognostic (2.74e-1)" "unprognostic (1.41e-2)" "unprognostic (2.85e-2)" "potential prognostic unfavorable (2.45e-6)" "unprognostic (2.85e-3)" "unprognostic (1.12e-2)" "potential prognostic unfavorable (9.22e-5)" "unprognostic (1.64e-2)" "potential prognostic unfavorable (6.21e-5)" "unprognostic (4.87e-3)" "unprognostic (2.48e-3)" "unprognostic (2.63e-1)" "unprognostic (3.27e-1)" "unprognostic (5.64e-2)" "unprognostic (4.64e-2)" "unprognostic (3.64e-1)" "unprognostic (1.17e-1)" "unprognostic (1.23e-1)" "unprognostic (1.49e-1)" "unprognostic (5.75e-3)" "unprognostic (2.80e-1)" "unprognostic (8.47e-3)" "unprognostic (2.86e-1)" "unprognostic (1.90e-1)" DAPK1 DAPK ENSG00000196730 "Death associated protein kinase 1" P53355 9 87497228-87708634 "Cancer-related genes, Enzymes, Human disease related genes, Predicted membrane proteins" "Apoptosis, Translation regulation" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epicardial cells: 707.3;Hematopoietic stem cells: 614.8;Mesothelial cells: 809.7;Renal collecting duct principal cells: 550.9;Transitional alveolar cells: 532.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 6.7;eosinophil: 8.7;intermediate monocyte: 14.0;myeloid DC: 4.8;non-classical monocyte: 15.3;plasmacytoid DC: 6.2" "Group enriched" "Detected in many" 56 "dendritic cells: 6.2;granulocytes: 8.7;monocytes: 15.3" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Skeletal muscle - Fibroblasts, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003516, CAB037302, HPA040472, HPA048436" Approved Approved Centrosome NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 61: Non-specific - Transcription" "Cluster 29: Forebrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 45 Centrosome "CAB037302: , HPA003516: , HPA040472: , HPA048436: " "unprognostic (1.67e-3)" "unprognostic (1.15e-1)" "unprognostic (1.55e-1)" "unprognostic (1.80e-1)" "unprognostic (9.84e-3)" "unprognostic (5.11e-3)" "unprognostic (2.55e-1)" "unprognostic (1.12e-3)" "unprognostic (1.17e-1)" "unprognostic (3.40e-3)" "potential prognostic favorable (5.29e-6)" "unprognostic (4.55e-3)" "unprognostic (3.96e-1)" "unprognostic (6.60e-2)" "unprognostic (2.00e-1)" "unprognostic (9.92e-2)" "unprognostic (7.40e-2)" "unprognostic (2.13e-1)" "unprognostic (2.48e-1)" "unprognostic (7.49e-3)" "unprognostic (6.50e-2)" "unprognostic (1.85e-2)" "unprognostic (2.72e-1)" "unprognostic (4.49e-3)" "unprognostic (1.10e-2)" "unprognostic (9.13e-2)" "unprognostic (1.09e-3)" "unprognostic (5.14e-2)" "unprognostic (5.38e-1)" "unprognostic (1.72e-1)" "unprognostic (3.60e-2)" DAPK2 "DRP-1, MGC119312" ENSG00000035664 "Death associated protein kinase 2" Q9UIK4 15 63907036-64072033 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 45.4;thyroid gland: 39.7" "Cell type enhanced" "Detected in many" "Adipocytes: 361.0;Alveolar cells type 1: 785.8;Cardiomyocytes: 281.1;Foveolar cells: 267.3;Myonuclei: 1089.6;Neutrophils: 415.8;Thymic myoid cells: 833.5;Transitional alveolar cells: 353.5" "Cell type enhanced" "Detected in many" "fibroblast: 68.0;oligodendrocyte: 179.9" "Cancer enriched" "Detected in all" 14 "Thyroid Carcinoma (TCGA): 153.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 15 "basophil: 64.8;eosinophil: 138.6;neutrophil: 39.2" "Lineage enriched" "Detected in many" 26 "granulocytes: 138.6" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 1, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Fibroblasts, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA071581 Supported "Golgi apparatus,Vesicles" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 11: White matter - Signal transduction" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 1 "Golgi apparatus, Vesicles" "HPA071581: " "unprognostic (6.78e-2)" "unprognostic (1.55e-1)" "unprognostic (5.16e-2)" "unprognostic (3.07e-2)" "unprognostic (5.00e-2)" "unprognostic (2.83e-1)" "unprognostic (4.20e-3)" "unprognostic (1.76e-2)" "unprognostic (8.97e-3)" "unprognostic (9.46e-2)" "unprognostic (7.74e-3)" "unprognostic (3.39e-1)" "unprognostic (3.70e-3)" "unprognostic (3.87e-1)" "unprognostic (1.50e-2)" "potential prognostic favorable (1.03e-6)" "unprognostic (4.16e-1)" "unprognostic (4.02e-1)" "unprognostic (1.80e-1)" "unprognostic (1.65e-1)" "unprognostic (1.52e-1)" "unprognostic (1.21e-1)" "unprognostic (3.26e-1)" "unprognostic (1.51e-1)" "unprognostic (2.69e-2)" "unprognostic (5.16e-2)" "unprognostic (3.72e-1)" "unprognostic (8.45e-2)" "unprognostic (1.74e-1)" "unprognostic (1.43e-2)" "unprognostic (3.64e-3)" DAPK3 "ZIP, ZIPK" ENSG00000167657 "Death associated protein kinase 3" O43293 19 3958453-3971123 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Transcription, Transcription regulation, Translation regulation" "Activator, Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 168.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028569 Approved Supported "Nucleoplasm,Vesicles,Primary cilium,Cytosol" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 74: Non-specific - Signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 62: Smooth muscle cells - Muscle contraction" 15 "Nucleoplasm, Cytosol" "Vesicles, Primary cilium" "HPA028569: " "unprognostic (8.38e-2)" "unprognostic (5.74e-2)" "unprognostic (8.91e-2)" "unprognostic (1.08e-2)" "unprognostic (3.35e-1)" "unprognostic (9.85e-2)" "unprognostic (2.49e-1)" "unprognostic (3.08e-1)" "unprognostic (4.19e-1)" "unprognostic (1.78e-2)" "unprognostic (1.75e-3)" "unprognostic (9.76e-2)" "unprognostic (2.38e-2)" "unprognostic (1.06e-2)" "unprognostic (1.47e-1)" "unprognostic (2.13e-1)" "unprognostic (5.75e-2)" "unprognostic (2.26e-1)" "unprognostic (1.34e-1)" "unprognostic (2.91e-1)" "unprognostic (3.96e-1)" "unprognostic (1.13e-1)" "unprognostic (1.50e-1)" "unprognostic (1.38e-1)" "unprognostic (1.45e-1)" "unprognostic (5.36e-3)" "unprognostic (1.54e-2)" "unprognostic (1.39e-1)" "unprognostic (1.94e-1)" "unprognostic (2.67e-2)" "unprognostic (6.54e-2)" DAPL1 ENSG00000163331 "Death associated protein like 1" A0PJW8 2 158795317-158862781 "Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Differentiation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 185.8;esophagus: 233.8;skin 1: 292.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 208.6;Epididymal principal cells: 281.3;Esophageal basal cells: 930.0;Esophageal suprabasal cells: 1285.0;Fallopian secretory cells: 412.1;Müller glia: 579.1;Ocular epithelial cells: 637.6;Suprabasal keratinocytes: 360.6" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 67.9;deep-layer near-projecting: 37.4;mammillary body: 34.2" "Group enriched" "Detected in all" 8 "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 73.4;Head and Neck Squamous Cell Carcinoma (TCGA): 79.1;Lung Squamous Cell Carcinoma (TCGA): 209.8;Ovary Serous Cystadenocarcinoma (TCGA): 246.5;Thyroid Carcinoma (TCGA): 165.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in many" 11 "prostate cancer: 275.2" "Minor Salivary Gland - Minor salivary gland basal cells, Pituitary gland - Thyrotropes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" "HPA046937, HPA058635" Enhanced Approved "Nucleoplasm,Nuclear bodies,Microtubules" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 58: Skin - Keratinization" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 60: Prostate cancer - Unknown function" "Cluster 100: Stratified epithelial cells - Barrier functions" 4 "Nucleoplasm, Nuclear bodies, Microtubules" "HPA046937: , HPA058635: " "unprognostic (3.05e-1)" "potential prognostic favorable (1.87e-6)" "unprognostic (3.51e-2)" "potential prognostic favorable (7.58e-4)" "unprognostic (7.28e-2)" "unprognostic (2.32e-2)" "unprognostic (2.31e-1)" "unprognostic (3.70e-2)" "unprognostic (2.90e-2)" "unprognostic (1.74e-1)" "unprognostic (1.40e-3)" "unprognostic (2.21e-2)" "unprognostic (3.36e-2)" "unprognostic (3.62e-1)" "unprognostic (4.07e-3)" "unprognostic (9.77e-2)" "unprognostic (1.54e-2)" "unprognostic (1.63e-1)" "unprognostic (1.12e-1)" "unprognostic (1.47e-1)" "unprognostic (7.90e-2)" "unprognostic (2.59e-1)" "unprognostic (2.13e-1)" "unprognostic (3.28e-1)" "unprognostic (1.99e-1)" "unprognostic (5.09e-2)" "unprognostic (2.26e-2)" "unprognostic (1.57e-1)" "unprognostic (3.78e-2)" "unprognostic (2.54e-1)" DAPP1 BAM32 ENSG00000070190 "Dual adaptor of phosphotyrosine and 3-phosphoinositides 1" Q9UN19 4 99816827-99870190 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 23.5;lymphoid tissue: 36.1" "Cell type enhanced" "Detected in many" "cDC: 284.6;Esophageal apical cells: 798.2;Esophageal suprabasal cells: 208.0;Megakaryocytes: 253.4;Neutrophils: 169.4;Ocular epithelial cells: 253.2;Plasma cells: 186.7;Platelets: 816.2;Suprabasal keratinocytes: 214.2;Urothelial cells: 714.3" "Group enriched" "Detected in some" 11 "central nervous system macrophage: 62.0;leukocyte: 36.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "lymphoma: 29.6" "Adrenal gland - Macrophages, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB033822, HPA046074" Approved NA NA 76000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 69: Urothelial cells - Basic cellular functions" 13 "CAB033822: , HPA046074: " "unprognostic (1.51e-2)" "unprognostic (1.86e-1)" "unprognostic (3.02e-2)" "unprognostic (6.35e-2)" "unprognostic (1.45e-1)" "unprognostic (1.42e-2)" "unprognostic (5.38e-2)" "unprognostic (4.94e-2)" "unprognostic (7.50e-2)" "unprognostic (1.96e-1)" "unprognostic (2.97e-2)" "unprognostic (3.35e-3)" "unprognostic (1.67e-1)" "unprognostic (3.88e-1)" "potential prognostic unfavorable (5.74e-4)" "unprognostic (2.52e-2)" "unprognostic (2.14e-2)" "unprognostic (2.50e-1)" "unprognostic (3.47e-1)" "unprognostic (4.29e-3)" "unprognostic (4.59e-2)" "unprognostic (1.40e-1)" "unprognostic (2.29e-1)" "unprognostic (2.36e-1)" "unprognostic (3.75e-1)" "unprognostic (4.76e-2)" "unprognostic (1.78e-1)" "unprognostic (2.58e-2)" DARS1 DARS ENSG00000115866 "Aspartyl-tRNA synthetase 1" P14868 2 135905881-135986100 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020451, HPA029804, HPA029805" Enhanced Enhanced Cytosol NA NA 250000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 51 Cytosol "HPA020451: , HPA029804: , HPA029805: " "unprognostic (4.61e-1)" "unprognostic (1.11e-3)" "potential prognostic unfavorable (2.17e-4)" "unprognostic (2.61e-2)" "unprognostic (7.04e-2)" "unprognostic (7.78e-2)" "unprognostic (1.51e-1)" "unprognostic (1.68e-1)" "unprognostic (4.83e-2)" "validated prognostic favorable (5.47e-8)" "validated prognostic favorable (1.45e-4)" "unprognostic (1.78e-2)" "unprognostic (1.19e-2)" "unprognostic (1.89e-2)" "unprognostic (1.66e-3)" "unprognostic (5.29e-1)" "unprognostic (9.32e-2)" "unprognostic (9.18e-2)" "unprognostic (1.44e-3)" "unprognostic (2.23e-3)" "potential prognostic unfavorable (9.14e-4)" "unprognostic (1.43e-1)" "unprognostic (4.72e-2)" "unprognostic (1.81e-2)" "unprognostic (1.04e-2)" "unprognostic (3.59e-2)" "unprognostic (1.65e-1)" "unprognostic (9.78e-2)" "unprognostic (8.11e-2)" DARS2 "FLJ10514, mtAspRS" ENSG00000117593 "Aspartyl-tRNA synthetase 2, mitochondrial" Q6PI48 1 173824653-173858808 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 57.6;Cardiomyocytes: 62.7;Epicardial cells: 143.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026506, HPA026528" Enhanced Supported Nucleoplasm,Mitochondria NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 45: Non-specific - Nuclear processes" "Cluster 20: Non-specific - Transcription regulation" 54 Mitochondria Nucleoplasm "HPA026506: , HPA026528: " "unprognostic (8.49e-3)" "unprognostic (1.59e-2)" "unprognostic (3.18e-2)" "unprognostic (9.63e-2)" "unprognostic (9.57e-2)" "unprognostic (3.84e-2)" "unprognostic (4.26e-2)" "unprognostic (2.36e-1)" "unprognostic (4.15e-2)" "unprognostic (1.25e-3)" "potential prognostic favorable (1.01e-4)" "unprognostic (1.36e-1)" "unprognostic (3.01e-2)" "unprognostic (1.25e-3)" "potential prognostic unfavorable (5.12e-4)" "potential prognostic unfavorable (4.42e-4)" "unprognostic (2.08e-1)" "unprognostic (5.40e-2)" "unprognostic (1.80e-1)" "unprognostic (2.78e-1)" "unprognostic (1.34e-1)" "unprognostic (1.85e-3)" "unprognostic (1.29e-1)" "unprognostic (1.28e-1)" "unprognostic (2.98e-1)" "unprognostic (4.74e-2)" "unprognostic (1.22e-1)" "unprognostic (9.57e-2)" "unprognostic (1.59e-1)" "unprognostic (7.01e-2)" "unprognostic (5.71e-2)" DAW1 "DNAAF18, FLJ25955, ODA16, WDR69" ENSG00000123977 "Dynein assembly factor with WD repeats 1" Q8N136 2 227871054-227924344 "Predicted intracellular proteins" "Ciliopathy, Disease variant, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "choroid plexus: 55.4;fallopian tube: 30.8;testis: 48.2" "Group enriched" "Detected in some" 4 "Choroid plexus epithelial cells: 145.8;Early spermatids: 105.7;Ependymal cells: 309.4;Epididymal efferent duct ciliated cells: 135.1;Fallopian tube ciliated cells: 183.6;Late primary spermatocytes: 388.1;Late spermatids: 331.7;Respiratory ciliated cells: 225.2" "Group enriched" "Detected in many" 7 "choroid plexus epithelial cell: 138.1;ependymal cell: 340.8" "Cancer enhanced" "Detected in some" "Lung Adenocarcinoma (TCGA): 2.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 10.0" "Adipose visceral - Mesothelial cells, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "midbrain: 20.8" HPA046118 Approved Approved "Plasma membrane,Mid piece,Principal piece,End piece" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 72: Neuronal - Signal transduction" "Cluster 34: Ciliated cells - Cilia assembly & function" "Mid piece, Principal piece, End piece" "Plasma membrane" "HPA046118: " "potential prognostic favorable (5.03e-4)" "unprognostic (6.74e-2)" "unprognostic (3.16e-2)" "unprognostic (3.88e-2)" "unprognostic (6.15e-2)" "unprognostic (5.82e-2)" "unprognostic (5.17e-3)" DAXX DAP6 ENSG00000204209 "Death domain associated protein" Q9UER7 6 33318558-33323016 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Transcription, Transcription regulation" "Chaperone, Chromatin regulator, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 60.2;Early primary spermatocytes: 48.7;Epididymal principal cells: 87.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002224, HPA008736, HPA008797, CAB025546, HPA065779" Enhanced Enhanced "Nucleoplasm,Nuclear bodies" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" 204 "Nucleoplasm, Nuclear bodies" "CAB002224: , CAB025546: , HPA008736: , HPA008797: , HPA065779: " "unprognostic (2.52e-1)" "unprognostic (7.50e-2)" "unprognostic (1.33e-1)" "unprognostic (9.31e-2)" "unprognostic (1.55e-1)" "unprognostic (2.93e-2)" "unprognostic (1.02e-2)" "unprognostic (1.41e-2)" "unprognostic (2.27e-1)" "unprognostic (4.06e-1)" "unprognostic (4.32e-2)" "unprognostic (1.10e-1)" "unprognostic (8.82e-2)" "unprognostic (2.15e-2)" "unprognostic (1.76e-3)" "unprognostic (1.59e-2)" "unprognostic (3.75e-1)" "unprognostic (1.29e-1)" "unprognostic (2.40e-2)" "unprognostic (6.53e-2)" "unprognostic (1.25e-1)" "unprognostic (5.08e-2)" "unprognostic (1.80e-2)" "unprognostic (2.82e-3)" "unprognostic (4.01e-3)" "unprognostic (1.68e-1)" "potential prognostic favorable (7.91e-4)" "unprognostic (2.08e-1)" "unprognostic (1.22e-2)" "potential prognostic unfavorable (1.58e-5)" "unprognostic (2.37e-1)" DAZ1 "DAZ, SPGY" ENSG00000188120 "Deleted in azoospermia 1" Q9NQZ3 Y 23129355-23199010 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 18 "testis: 1.9" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 2.2;Early primary spermatocytes: 1.2;Gastric chief cells: 1.1;Undifferentiated spermatogonia: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Myeloma: 2.4;Neuroblastoma: 1.9" HPA047113 Supported NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 20: Myeloma - Immune response" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 13 "HPA047113: " "unprognostic (2.00e-1)" DAZ2 "MGC126442, pDP1678" ENSG00000205944 "Deleted in azoospermia 2" Q13117 Y 23219447-23291356 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 17 "stomach 1: 5.0;testis: 2.8" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Stomach Adenocarcinoma (TCGA): 6.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 3.4;Neuroblastoma: 5.5" HPA047113 Approved NA NA "Cluster 21: Testis - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" "HPA047113: " "unprognostic (3.41e-1)" "unprognostic (4.60e-2)" DAZ3 ENSG00000187191 "Deleted in azoospermia 3" Q9NR90 Y 24763069-24813492 "Disease related genes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "testis: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047113 Approved NA NA "Cluster 47: Testis - Mixed function" "Cluster 20: Myeloma - Immune response" "HPA047113: " DAZ4 ENSG00000205916 "Deleted in azoospermia 4" Q86SG3 Y 24833843-24907040 "Disease related genes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 40 "stomach 1: 24.4;testis: 10.8" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Stomach Adenocarcinoma (TCGA): 4.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 7.2;Myeloma: 15.5;Neuroblastoma: 10.3" HPA047113 Approved NA NA "Cluster 60: Stomach - Digestion" "Cluster 20: Myeloma - Immune response" "Cluster 106: Spermatogonia - Spermatogonial differentiation" "HPA047113: " "unprognostic (4.41e-2)" "unprognostic (3.85e-2)" DAZAP1 MGC19907 ENSG00000071626 "DAZ associated protein 1" Q96EP5 19 1407569-1435687 "Plasma proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004201, HPA004631" Enhanced Supported Nucleoplasm,Midbody,Cytosol Yes NA 83000 "Cluster 13: Non-specific - Mitochondria" "Cluster 47: Testis - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 23: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 17 Nucleoplasm "Midbody, Cytosol" "HPA004201: , HPA004631: " "unprognostic (1.29e-1)" "unprognostic (1.69e-1)" "unprognostic (1.68e-1)" "unprognostic (4.16e-2)" "unprognostic (1.18e-2)" "unprognostic (3.53e-1)" "unprognostic (1.35e-2)" "unprognostic (8.09e-3)" "unprognostic (1.33e-2)" "unprognostic (7.09e-3)" "unprognostic (2.27e-1)" "unprognostic (5.17e-2)" "unprognostic (1.02e-1)" "potential prognostic unfavorable (1.46e-5)" "unprognostic (1.34e-3)" "unprognostic (2.08e-2)" "unprognostic (2.90e-3)" "unprognostic (4.13e-1)" "unprognostic (1.37e-2)" "unprognostic (2.57e-1)" "unprognostic (9.72e-3)" "unprognostic (1.69e-1)" "unprognostic (1.24e-2)" "unprognostic (1.35e-2)" "unprognostic (8.73e-3)" "potential prognostic favorable (2.19e-4)" "unprognostic (6.46e-2)" "unprognostic (1.43e-2)" "unprognostic (3.20e-1)" "unprognostic (1.33e-1)" "unprognostic (2.17e-3)" DAZAP2 KIAA0058 ENSG00000183283 "DAZ associated protein 2" Q15038 12 51238724-51271362 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Kupffer cells: 539.1;Neutrophils: 767.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Colon - Macrophages, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045940 Supported "Nuclear speckles" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 153 "Nuclear speckles" "HPA045940: " "unprognostic (2.30e-3)" "unprognostic (1.16e-2)" "unprognostic (1.94e-1)" "unprognostic (1.76e-3)" "unprognostic (2.80e-1)" "unprognostic (3.96e-2)" "unprognostic (6.30e-2)" "unprognostic (4.49e-2)" "unprognostic (1.19e-1)" "unprognostic (1.82e-2)" "potential prognostic favorable (1.12e-9)" "unprognostic (4.31e-2)" "unprognostic (7.84e-2)" "unprognostic (2.10e-1)" "unprognostic (8.51e-2)" "unprognostic (2.69e-1)" "unprognostic (4.25e-2)" "unprognostic (4.47e-2)" "unprognostic (1.51e-1)" "unprognostic (1.18e-1)" "unprognostic (1.54e-1)" "unprognostic (4.43e-3)" "unprognostic (2.37e-1)" "unprognostic (3.67e-1)" "unprognostic (1.63e-1)" "unprognostic (1.90e-1)" "unprognostic (4.86e-2)" "unprognostic (1.33e-1)" "unprognostic (1.76e-1)" "unprognostic (8.03e-2)" "unprognostic (2.84e-2)" DAZL "DAZH, DAZL1, DAZLA, MGC26406, SPGYLA" ENSG00000092345 "Deleted in azoospermia like" Q92904 3 16586792-16670306 "Predicted intracellular proteins" "Differentiation, Spermatogenesis, Translation regulation" "Developmental protein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 79 "testis: 74.5" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 149.8;Early primary spermatocytes: 306.7;Early spermatids: 50.0;Late primary spermatocytes: 145.0;Late spermatids: 56.6;Oocytes: 46.1;Undifferentiated spermatogonia: 53.9" "Cell type enhanced" "Detected in single" "thalamic excitatory: 1.2" "Cancer enriched" "Detected in single" 41 "Testicular Germ Cell Tumor (TCGA): 24.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Gastric cancer: 1.0;lymphoma: 1.2" "Testis - Spermatocytes" "Region enhanced" "Detected in many" "basal ganglia: 10.1" "Not detected" "Not detected" "HPA019777, HPA047113" Enhanced NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 5: Rhabdoid - Unknown function" "Cluster 3: Early primary spermatocytes - Early meiosis" 6 "HPA019777: , HPA047113: " "unprognostic (2.03e-1)" "unprognostic (4.02e-1)" DBF4 "ASK, chif, DBF4A, ZDBF1" ENSG00000006634 "DBF4 zinc finger" Q9UBU7 7 87876216-87909553 "Essential proteins, Predicted intracellular proteins" "Cell cycle, DNA replication" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 24 "testis: 14.2" "Group enriched" "Detected in many" 4 "Early spermatids: 314.8;Late primary spermatocytes: 1165.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA042923 Supported "Nucleoplasm,Nuclear bodies" Yes Yes "Cluster 57: Testis - Spermatogenesis" "Cluster 48: Non-specific - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 15 "Nucleoplasm, Nuclear bodies" "HPA042923: " "unprognostic (1.05e-1)" "unprognostic (1.57e-2)" "unprognostic (1.99e-2)" "unprognostic (3.30e-3)" "unprognostic (6.66e-3)" "potential prognostic unfavorable (5.43e-5)" "unprognostic (2.03e-1)" "unprognostic (8.53e-3)" "unprognostic (9.63e-2)" DBF4B "ASKL1, chifb, DRF1, FLJ13087, ZDBF1B" ENSG00000161692 "DBF4 zinc finger B" Q8NFT6 17 44708608-44752264 "Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 90.9;Retinal amacrine cells: 45.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048465, HPA077959" Approved Supported Nucleoplasm,Vesicles NA Yes "Cluster 45: Eosinophils - Unknown function" "Cluster 21: Testis - Mixed function" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Breast cancer - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 3 Nucleoplasm Vesicles "HPA048465: , HPA077959: " "unprognostic (1.00e-2)" "unprognostic (2.16e-1)" "unprognostic (2.01e-1)" "unprognostic (1.61e-1)" "unprognostic (1.28e-2)" "unprognostic (8.46e-2)" "unprognostic (7.75e-3)" "unprognostic (3.45e-2)" "unprognostic (6.93e-2)" "unprognostic (1.11e-3)" "unprognostic (5.14e-2)" "unprognostic (1.80e-2)" "unprognostic (1.16e-2)" "potential prognostic favorable (1.61e-4)" "unprognostic (1.25e-1)" "unprognostic (2.74e-1)" "potential prognostic unfavorable (2.23e-4)" "unprognostic (5.38e-2)" "unprognostic (4.85e-3)" "unprognostic (4.13e-2)" "unprognostic (5.59e-2)" "unprognostic (4.28e-1)" "unprognostic (2.09e-1)" "unprognostic (8.22e-2)" DBH DBM ENSG00000123454 "Dopamine beta-hydroxylase" P09172 9 133636363-133659329 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Catecholamine biosynthesis" "Monooxygenase, Oxidoreductase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "adrenal gland: 257.4" "Cell type enriched" "Detected in some" 9 "Adrenal medulla cells: 893.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Liver Hepatocellular Carcinoma (TCGA): 2.5" "Region enriched" "Detected in many" 22 "pons: 513.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 24 "Neuroblastoma: 209.4" "Adrenal gland - Adrenal medulla cells, Pituitary gland - Corticotropes" "Region enriched" "Detected in some" 6 "pons and medulla: 22.1" "Region enriched" "Detected in single" 26 "pons: 22.1" "HPA002130, HPA005960, HPA070789" Enhanced Supported "Endoplasmic reticulum,Vesicles" "Intracellular and membrane" Enzyme NA NA 520000000 "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 18: Adrenal cortex cells - Steroidogensis" 18 Vesicles "Endoplasmic reticulum" "HPA002130: , HPA005960: , HPA070789: " "unprognostic (1.28e-2)" "unprognostic (7.34e-3)" "potential prognostic favorable (1.86e-5)" "unprognostic (1.57e-1)" DBI "ACBD1, ACBP" ENSG00000155368 "Diazepam binding inhibitor, acyl-CoA binding protein" P07108 2 119366924-119372550 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 1417.2;Esophageal apical cells: 4467.2;Esophageal basal cells: 1821.2;Esophageal suprabasal cells: 4734.8;Hepatocytes: 2459.3;Suprabasal keratinocytes: 1642.2" "Cell type enhanced" "Detected in all" "Bergmann glia: 151.6" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 1952.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051428 Approved NA NA 11000000 "Cluster 41: Basophils - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 85: Squamous epithelial cells - Keratinization" "HPA051428: " "unprognostic (6.91e-2)" "unprognostic (2.67e-1)" "unprognostic (8.45e-2)" "unprognostic (8.27e-3)" "unprognostic (7.44e-2)" "unprognostic (1.13e-2)" "unprognostic (1.73e-2)" "unprognostic (1.06e-1)" "unprognostic (1.43e-1)" "unprognostic (3.53e-3)" "potential prognostic unfavorable (7.46e-6)" "unprognostic (3.51e-1)" "unprognostic (7.50e-3)" "unprognostic (3.56e-3)" "potential prognostic unfavorable (4.00e-5)" "unprognostic (1.30e-1)" "unprognostic (2.01e-2)" "unprognostic (1.97e-2)" "unprognostic (6.31e-2)" "unprognostic (6.07e-2)" "unprognostic (3.07e-1)" "unprognostic (2.35e-2)" "unprognostic (6.09e-1)" "unprognostic (1.39e-1)" "unprognostic (1.14e-1)" "unprognostic (1.35e-1)" "unprognostic (6.72e-2)" "unprognostic (3.15e-1)" "unprognostic (2.17e-1)" "unprognostic (1.09e-1)" "unprognostic (7.31e-2)" DBN1 D0S117E ENSG00000113758 "Drebrin 1" Q16643 5 177456608-177474401 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Actin-binding, Developmental protein" "Alzheimer disease, Amyloidosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 124.1;Fibroblasts: 59.7;Late spermatids: 68.1;Platelets: 99.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "dendritic cells: 5.3;granulocytes: 9.2;T-cells: 13.3" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Liver - Vascular endothelial cells, Prostate - Smooth muscle cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051452, HPA056940" Enhanced Supported Approved "Plasma membrane,Actin filaments" NA NA 1500000 "Cluster 1: T-cells - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 108: Fibroblasts - ECM organization" 51 "Plasma membrane" "Actin filaments" "HPA051452: , HPA056940: " "unprognostic (1.99e-1)" "unprognostic (6.60e-2)" "unprognostic (6.84e-2)" "potential prognostic unfavorable (6.85e-4)" "unprognostic (1.48e-1)" "unprognostic (8.88e-2)" "unprognostic (2.11e-1)" "unprognostic (7.32e-2)" "unprognostic (1.52e-1)" "unprognostic (1.66e-3)" "unprognostic (5.00e-3)" "unprognostic (6.20e-2)" "unprognostic (1.71e-1)" "unprognostic (2.98e-3)" "unprognostic (1.17e-1)" "unprognostic (2.84e-3)" "unprognostic (4.54e-3)" "unprognostic (9.22e-2)" "unprognostic (5.33e-2)" "unprognostic (2.36e-2)" "unprognostic (3.86e-1)" "unprognostic (1.89e-1)" "unprognostic (5.73e-3)" "unprognostic (3.08e-1)" "unprognostic (5.74e-2)" "unprognostic (1.68e-1)" "unprognostic (5.27e-2)" "unprognostic (1.08e-1)" "unprognostic (1.74e-1)" "unprognostic (8.82e-3)" "unprognostic (5.28e-2)" DBNDD1 "FLJ12582, MGC3101" ENSG00000003249 "Dysbindin domain containing 1" Q9H9R9 16 90004871-90019890 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 91.5;skeletal muscle: 46.9" "Cell type enhanced" "Detected in many" "Breast lactating cells: 23.4;Cardiomyocytes: 45.9;Cholangiocytes: 31.5;Epicardial cells: 18.2;Esophageal apical cells: 69.3;Esophageal suprabasal cells: 36.8" "Cell type enhanced" "Detected in many" "thalamic excitatory: 26.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "naive B-cell: 12.9" "Lineage enriched" "Detected in many" 4 "B-cells: 12.9" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043018 Uncertain Approved "Nuclear speckles,Cytosol,Equatorial segment,Mid piece,Principal piece,End piece" No No "Cluster 34: B-cells - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 85: Squamous epithelial cells - Keratinization" 1 "Nuclear speckles" "Cytosol, Equatorial segment, Mid piece, Principal piece, End piece" "HPA043018: " "unprognostic (7.83e-2)" "unprognostic (6.26e-2)" "unprognostic (4.39e-2)" "unprognostic (1.70e-2)" "unprognostic (2.35e-1)" "unprognostic (1.47e-2)" "unprognostic (7.20e-2)" "unprognostic (9.89e-3)" "unprognostic (1.40e-1)" "unprognostic (9.63e-3)" "unprognostic (1.91e-3)" "unprognostic (2.63e-1)" "potential prognostic favorable (1.84e-4)" "unprognostic (1.56e-1)" "unprognostic (5.16e-2)" "unprognostic (1.55e-1)" "unprognostic (6.52e-2)" "unprognostic (1.54e-1)" "unprognostic (4.37e-1)" "unprognostic (1.34e-1)" "unprognostic (2.41e-1)" "unprognostic (1.15e-1)" "unprognostic (3.30e-1)" "unprognostic (3.25e-2)" "unprognostic (3.06e-2)" "unprognostic (1.46e-1)" "unprognostic (5.65e-2)" "unprognostic (8.23e-2)" "unprognostic (3.60e-1)" "unprognostic (1.66e-1)" "unprognostic (1.37e-1)" DBNDD2 "C20orf35, HSMNP1" ENSG00000244274 "Dysbindin domain containing 2" Q9BQY9 20 45406057-45410610 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1567.7" "Cell type enriched" "Detected in some" 4 "Oligodendrocytes: 618.9" "Cell type enriched" "Detected in all" 4 "oligodendrocyte: 785.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 15 "dendritic cells: 18.8;monocytes: 12.5;T-cells: 9.2" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043991 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 62: Non-specific - Plasma proteins" "Cluster 80: Oligodendrocytes - Myelination" 2 "Nucleoplasm, Cytosol" "HPA043991: " "unprognostic (1.54e-2)" "unprognostic (6.48e-2)" "unprognostic (5.46e-2)" "unprognostic (1.40e-1)" "unprognostic (1.09e-1)" "unprognostic (6.91e-2)" "unprognostic (2.67e-1)" "unprognostic (6.15e-2)" "unprognostic (1.59e-1)" "unprognostic (2.38e-1)" "unprognostic (1.52e-1)" "unprognostic (7.28e-2)" "unprognostic (3.40e-1)" "unprognostic (2.31e-3)" "unprognostic (5.58e-2)" "unprognostic (1.78e-3)" "unprognostic (9.64e-3)" "unprognostic (2.21e-1)" "unprognostic (4.92e-2)" "unprognostic (2.06e-1)" "unprognostic (7.26e-2)" "unprognostic (3.08e-2)" "unprognostic (1.37e-1)" "unprognostic (1.09e-1)" "unprognostic (8.59e-2)" "unprognostic (1.21e-1)" "unprognostic (3.59e-3)" "unprognostic (2.03e-2)" "unprognostic (1.05e-1)" "unprognostic (1.32e-2)" "unprognostic (1.57e-1)" DBNL "ABP1, HIP-55, SH3P7" ENSG00000136279 "Drebrin like" Q9UJU6 7 44044640-44069456 "Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Endocytosis, Immunity, Transport" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 950.6;Esophageal suprabasal cells: 366.6;Hofbauer cells: 222.7;Megakaryocytes: 315.3;Platelets: 371.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020265, HPA027735" Enhanced Supported "Vesicles,Plasma membrane" NA NA 6400000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 67: Non-specific - Unknown function" "Cluster 47: Platelets - Hemostasis" 36 "Vesicles, Plasma membrane" "HPA020265: , HPA027735: " "unprognostic (7.80e-2)" "unprognostic (1.40e-1)" "unprognostic (3.37e-1)" "unprognostic (3.37e-1)" "unprognostic (1.09e-1)" "unprognostic (3.34e-2)" "potential prognostic unfavorable (3.16e-5)" "unprognostic (3.34e-2)" "unprognostic (9.43e-2)" "unprognostic (1.03e-1)" "unprognostic (5.43e-3)" "unprognostic (6.32e-2)" "unprognostic (1.34e-3)" "potential prognostic unfavorable (7.01e-4)" "unprognostic (1.02e-2)" "potential prognostic unfavorable (5.48e-4)" "unprognostic (1.80e-2)" "unprognostic (1.96e-1)" "unprognostic (1.05e-1)" "unprognostic (6.86e-3)" "unprognostic (1.62e-1)" "unprognostic (1.16e-1)" "unprognostic (1.66e-1)" "unprognostic (7.20e-2)" "unprognostic (2.98e-1)" "unprognostic (2.56e-1)" "unprognostic (6.22e-2)" "unprognostic (2.22e-1)" "unprognostic (1.57e-1)" "unprognostic (1.07e-1)" "unprognostic (6.15e-2)" DBP DABP ENSG00000105516 "D-box binding PAR bZIP transcription factor" Q10586 19 48630030-48637379 "Metabolic proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Müller glia: 153.9;Retinal amacrine cells: 78.4;Retinal bipolar cells: 194.5;Retinal horizontal cells: 132.2;Retinal pigment epithelial cells: 102.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 2: Non-specific - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 4 "unprognostic (5.92e-3)" "unprognostic (3.58e-1)" "unprognostic (3.63e-1)" "unprognostic (2.55e-3)" "unprognostic (2.18e-2)" "unprognostic (1.33e-1)" "unprognostic (2.66e-2)" "unprognostic (2.58e-1)" "unprognostic (1.03e-2)" "unprognostic (6.56e-2)" "potential prognostic favorable (6.81e-5)" "unprognostic (1.94e-2)" "unprognostic (2.55e-2)" "unprognostic (1.53e-1)" "potential prognostic favorable (6.39e-5)" "potential prognostic favorable (6.84e-4)" "unprognostic (3.84e-1)" "potential prognostic favorable (6.70e-4)" "unprognostic (1.60e-1)" "unprognostic (2.05e-1)" "unprognostic (5.93e-2)" "unprognostic (1.10e-2)" "potential prognostic favorable (4.68e-4)" "unprognostic (2.46e-1)" "potential prognostic unfavorable (6.13e-4)" "unprognostic (2.65e-1)" "unprognostic (9.17e-2)" "unprognostic (2.37e-2)" "unprognostic (2.07e-1)" "unprognostic (6.70e-2)" "unprognostic (2.60e-2)" DBR1 ENSG00000138231 "Debranching RNA lariats 1" Q9UK59 3 138160988-138174949 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "mRNA processing" Hydrolase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035365 Supported Approved Nucleoplasm NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 54: Non-specific - Ribosome" "Cluster 55: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 7 Nucleoplasm "HPA035365: " "unprognostic (2.18e-2)" "unprognostic (1.97e-1)" "unprognostic (2.58e-2)" "unprognostic (2.12e-1)" "unprognostic (1.34e-1)" "unprognostic (5.69e-3)" "unprognostic (3.96e-1)" "unprognostic (1.01e-1)" "unprognostic (1.85e-1)" "unprognostic (3.69e-2)" "potential prognostic favorable (4.12e-6)" "unprognostic (3.33e-3)" "unprognostic (2.90e-3)" "unprognostic (4.41e-3)" "unprognostic (2.49e-2)" "unprognostic (1.23e-1)" "unprognostic (7.43e-2)" "unprognostic (2.72e-2)" "unprognostic (1.29e-2)" "unprognostic (3.32e-1)" "unprognostic (7.39e-2)" "unprognostic (1.25e-1)" "unprognostic (1.58e-1)" "unprognostic (4.82e-2)" "unprognostic (2.47e-2)" "unprognostic (7.70e-2)" "unprognostic (1.38e-2)" "unprognostic (1.33e-1)" "unprognostic (1.64e-1)" "unprognostic (3.32e-1)" "unprognostic (1.37e-1)" DBT "BCKAD-E2, BCKDH-E2, BCOADC-E2" ENSG00000137992 "Dihydrolipoamide branched chain transacylase E2" P11182 1 100186919-100249834 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Acyltransferase, Transferase" "Disease variant, Maple syrup urine disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Parietal cells: 141.4;Prostatic glandular cells: 104.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 66.5" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Stomach - Parietal cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026481, HPA026485, HPA026533" Enhanced Supported Mitochondria NA NA "Cluster 24: Non-specific - Transcription" "Cluster 76: Non-specific - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 41 Mitochondria "HPA026481: , HPA026485: , HPA026533: " "unprognostic (3.47e-3)" "unprognostic (1.72e-2)" "unprognostic (8.60e-2)" "unprognostic (8.11e-2)" "unprognostic (7.39e-3)" "unprognostic (1.53e-1)" "unprognostic (1.24e-2)" "unprognostic (6.64e-3)" "unprognostic (1.06e-1)" "unprognostic (1.10e-1)" "validated prognostic favorable (3.24e-8)" "validated prognostic favorable (3.36e-5)" "unprognostic (6.11e-2)" "unprognostic (1.67e-1)" "unprognostic (7.82e-2)" "unprognostic (4.96e-2)" "unprognostic (4.80e-2)" "unprognostic (2.68e-1)" "unprognostic (2.11e-1)" "unprognostic (4.19e-2)" "unprognostic (9.47e-3)" "unprognostic (2.18e-3)" "unprognostic (3.02e-2)" "unprognostic (2.07e-1)" "unprognostic (1.73e-3)" "unprognostic (6.53e-2)" "unprognostic (3.27e-2)" "unprognostic (4.06e-1)" "unprognostic (3.51e-1)" "unprognostic (9.99e-2)" "unprognostic (6.23e-2)" DBX1 ENSG00000109851 "Developing brain homeobox 1" A6NMT0 11 20156155-20160475 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 16 "Rhabdoid: 11.0;Sarcoma: 12.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA039802 Uncertain NA NA "Cluster 33: Sarcoma - Muscle contraction" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" "HPA039802: " DBX2 FLJ16139 ENSG00000185610 "Developing brain homeobox 2" Q6ZNG2 12 45014672-45051099 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "brain: 3.4" "Group enriched" "Detected in some" 5 "Adipocytes: 8.6;Astrocytes: 17.4;Bergmann glia: 5.5;Fibro-adipogenic progenitors: 10.2;Oligodendrocyte progenitor cells: 21.8;Undifferentiated spermatogonia: 12.3" "Group enriched" "Detected in some" 5 "astrocyte: 25.6;Bergmann glia: 7.1;oligodendrocyte precursor cell: 27.2" "Cancer enriched" "Detected in single" 32 "Glioblastoma Multiforme (TCGA): 6.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065045, HPA066053" Uncertain Approved "Nucleoplasm,Nuclear membrane,Vesicles" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 28: Astrocytes - Homeostasis & neuron support" "Nucleoplasm, Nuclear membrane" Vesicles "HPA065045: , HPA066053: " "unprognostic (9.91e-2)" "unprognostic (1.75e-2)" "potential prognostic unfavorable (5.62e-4)" DCAF1 "KIAA0800, MGC102804, VPRBP" ENSG00000145041 "DDB1 and CUL4 associated factor 1" Q9Y4B6 3 51395867-51500015 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation, Ubl conjugation pathway" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 47.6" "Group enriched" "Detected in many" 4 "Early spermatids: 174.4;Late spermatids: 540.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036142, HPA052445, HPA053203" Approved Supported "Nucleoplasm,Nucleoli fibrillar center" No No "Cluster 24: Non-specific - Transcription" "Cluster 39: Testis - Nuclear processes" "Cluster 25: Non-specific - Transcription" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 75 Nucleoplasm "Nucleoli fibrillar center" "HPA036142: , HPA052445: , HPA053203: " "unprognostic (2.87e-2)" "unprognostic (3.55e-1)" "unprognostic (2.79e-2)" "unprognostic (2.18e-1)" "unprognostic (1.02e-1)" "unprognostic (5.54e-2)" "unprognostic (3.28e-1)" "unprognostic (3.05e-2)" "unprognostic (7.87e-2)" "potential prognostic favorable (5.09e-4)" "unprognostic (2.13e-3)" "unprognostic (3.25e-2)" "unprognostic (4.74e-2)" "unprognostic (4.78e-2)" "unprognostic (1.17e-2)" "unprognostic (6.68e-2)" "unprognostic (5.13e-3)" "unprognostic (9.94e-2)" "unprognostic (3.00e-2)" "unprognostic (3.28e-2)" "unprognostic (1.34e-1)" "unprognostic (2.53e-2)" "unprognostic (3.22e-2)" "unprognostic (1.31e-1)" "unprognostic (3.27e-1)" "unprognostic (7.77e-2)" "unprognostic (2.42e-1)" "unprognostic (3.42e-2)" "unprognostic (3.14e-1)" DCAF10 "FLJ23201, MGC10765, WDR32" ENSG00000122741 "DDB1 and CUL4 associated factor 10" Q5QP82 9 37800554-37867666 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 571.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024160 Uncertain Approved "Nucleoli fibrillar center" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 31 "Nucleoli fibrillar center" "HPA024160: " "unprognostic (1.06e-1)" "unprognostic (1.03e-1)" "unprognostic (6.55e-2)" "unprognostic (8.75e-2)" "unprognostic (7.65e-2)" "unprognostic (4.83e-2)" "unprognostic (5.46e-2)" "unprognostic (1.40e-1)" "unprognostic (8.14e-2)" "unprognostic (1.12e-2)" "validated prognostic favorable (1.13e-5)" "validated prognostic favorable (5.25e-4)" "unprognostic (2.71e-1)" "unprognostic (1.49e-1)" "unprognostic (1.57e-1)" "unprognostic (1.74e-1)" "unprognostic (3.12e-2)" "unprognostic (5.43e-2)" "unprognostic (6.45e-2)" "unprognostic (1.65e-2)" "unprognostic (2.00e-2)" "unprognostic (8.36e-2)" "unprognostic (9.71e-2)" "unprognostic (1.83e-2)" "unprognostic (1.67e-2)" "unprognostic (2.05e-1)" "unprognostic (3.86e-2)" "unprognostic (1.40e-1)" "unprognostic (2.35e-1)" "unprognostic (2.64e-2)" "unprognostic (3.46e-2)" DCAF11 "GL014, PRO2389, WDR23" ENSG00000100897 "DDB1 and CUL4 associated factor 11" Q8TEB1 14 24114195-24125242 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 13.4;Bergmann glia: 14.0;Brain excitatory neurons: 12.4;Brain inhibitory neurons: 10.1;Choroid plexus epithelial cells: 12.0;Ependymal cells: 12.8;Microglia: 13.5;Oligodendrocyte progenitor cells: 12.0;Oligodendrocytes: 14.1;Other brain neurons: 10.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003583, HPA031157" Approved Enhanced Nucleoplasm NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 70: Non-specific - Protein processing" "Cluster 51: Neurons - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 22: Non-specific - Basic cellular functions" 38 Nucleoplasm "HPA003583: , HPA031157: " "unprognostic (2.89e-1)" "unprognostic (2.34e-2)" "unprognostic (1.20e-1)" "unprognostic (9.69e-2)" "unprognostic (4.43e-1)" "unprognostic (1.15e-1)" "unprognostic (9.45e-2)" "potential prognostic favorable (1.92e-4)" "unprognostic (5.43e-2)" "unprognostic (3.18e-3)" "potential prognostic favorable (3.08e-4)" "unprognostic (6.03e-3)" "unprognostic (3.41e-3)" "unprognostic (1.47e-2)" "unprognostic (2.97e-2)" "unprognostic (7.24e-2)" "unprognostic (3.07e-3)" "unprognostic (7.08e-2)" "unprognostic (1.79e-2)" "unprognostic (1.32e-1)" "unprognostic (8.76e-2)" "unprognostic (1.05e-1)" "unprognostic (3.87e-2)" "unprognostic (5.10e-1)" "unprognostic (2.93e-2)" "unprognostic (1.30e-2)" "unprognostic (3.00e-1)" "unprognostic (3.36e-2)" "unprognostic (1.48e-1)" "unprognostic (4.05e-2)" "unprognostic (4.61e-1)" DCAF12 "CT102, DKFZP434O125, KIAA1892, MGC1058, TCC52, WDR40A" ENSG00000198876 "DDB1 and CUL4 associated factor 12" Q5T6F0 9 34086387-34127399 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 174.2;Erythrocytes: 402.3;Esophageal apical cells: 267.3;Kupffer cells: 129.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062279 Uncertain NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 39: Testis - Nuclear processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 12 "HPA062279: " "unprognostic (4.58e-2)" "unprognostic (2.25e-1)" "unprognostic (1.27e-2)" "unprognostic (6.82e-2)" "unprognostic (1.23e-1)" "unprognostic (4.98e-2)" "unprognostic (1.63e-1)" "unprognostic (2.56e-2)" "unprognostic (1.63e-1)" "unprognostic (8.42e-2)" "potential prognostic favorable (5.12e-7)" "unprognostic (3.26e-2)" "unprognostic (1.51e-1)" "unprognostic (2.17e-3)" "unprognostic (1.81e-2)" "unprognostic (1.48e-1)" "potential prognostic unfavorable (1.27e-5)" "unprognostic (2.28e-1)" "unprognostic (5.49e-2)" "unprognostic (5.19e-3)" "unprognostic (3.93e-1)" "unprognostic (6.76e-2)" "unprognostic (4.18e-1)" "unprognostic (2.25e-1)" "unprognostic (8.95e-2)" "unprognostic (4.40e-1)" "unprognostic (2.71e-2)" "unprognostic (6.46e-2)" "unprognostic (3.53e-1)" "unprognostic (2.32e-3)" "unprognostic (1.89e-1)" DCAF12L1 "KIAA1892L, WDR40B" ENSG00000198889 "DDB1 and CUL4 associated factor 12 like 1" Q5VU92 X 126549383-126552814 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 4.6;fallopian tube: 2.4;testis: 5.8" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 23.3;Early spermatids: 22.1;Epididymal efferent duct absorptive cells: 16.3;Epididymal efferent duct ciliated cells: 10.9;Epididymal principal cells: 13.1;Late spermatids: 71.6;Undifferentiated spermatogonia: 6.6" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney Renal Papillary Cell Carcinoma (TCGA): 3.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Kidney cancer: 5.6;ovarian cancer: 3.1;Uterine cancer: 3.0" "Adipose subcutaneous - Smooth muscle cells, Pituitary gland - Lactotropes" "HPA044737, HPA048981, HPA053138" Approved Uncertain Cytosol NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 3 Cytosol "HPA044737: , HPA048981: , HPA053138: " "unprognostic (1.78e-3)" "unprognostic (8.38e-2)" "unprognostic (3.21e-2)" "unprognostic (1.56e-1)" "unprognostic (1.88e-2)" "unprognostic (2.79e-1)" "unprognostic (8.57e-3)" DCAF12L2 WDR40C ENSG00000198354 "DDB1 and CUL4 associated factor 12 like 2" Q5VW00 X 126163499-126166289 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 20.2" "Cell type enhanced" "Detected in some" "Epididymal efferent duct absorptive cells: 14.9;Epididymal principal cells: 53.4;Oocytes: 4.6;Other brain neurons: 4.3;Peritubular myoid cells: 4.4;Sertoli cells: 8.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 1.4;prostate cancer: 1.3" "Adrenal gland - Adrenal medulla cells, Pituitary gland - Lactotropes, Testis - Sertoli cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA044737, HPA048981, HPA053138" Approved Uncertain Cytosol NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" 2 Cytosol "HPA044737: , HPA048981: , HPA053138: " "unprognostic (9.64e-2)" "unprognostic (9.89e-2)" "unprognostic (1.30e-1)" DCAF13 "DKFZP564O0463, Gm83, HSPC064, Sof1, WDSOF1" ENSG00000164934 "DDB1 and CUL4 associated factor 13" Q9NV06 8 103414714-103443453 "Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing, Ubl conjugation pathway" Ribonucleoprotein "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 153.2;Late primary spermatocytes: 150.1;Oocytes: 248.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044504 Uncertain Supported "Nucleoplasm,Nucleoli,Cell Junctions,Centrosome,Cytosol" NA NA 480000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 40: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 30 "Nucleoplasm, Nucleoli" "Cell Junctions, Centrosome, Cytosol" "HPA044504: " "unprognostic (2.53e-2)" "unprognostic (1.16e-3)" "unprognostic (3.81e-1)" "unprognostic (6.25e-3)" "unprognostic (1.02e-1)" "unprognostic (1.26e-1)" "unprognostic (1.24e-1)" "unprognostic (1.98e-3)" "unprognostic (2.08e-3)" "potential prognostic unfavorable (1.73e-4)" "unprognostic (1.66e-3)" "unprognostic (7.62e-2)" "potential prognostic unfavorable (1.52e-6)" "validated prognostic unfavorable (3.14e-8)" "validated prognostic unfavorable (1.53e-4)" "unprognostic (6.78e-3)" "unprognostic (6.74e-3)" "unprognostic (2.23e-1)" "unprognostic (2.56e-1)" "unprognostic (1.37e-2)" "unprognostic (1.22e-3)" "unprognostic (6.37e-3)" "unprognostic (1.97e-2)" "unprognostic (1.13e-2)" "unprognostic (1.08e-2)" "unprognostic (3.27e-1)" "unprognostic (9.84e-2)" "unprognostic (3.57e-1)" "unprognostic (2.22e-1)" "unprognostic (2.36e-2)" "unprognostic (1.73e-2)" DCAF15 "C19orf72, MGC99481" ENSG00000132017 "DDB1 and CUL4 associated factor 15" Q66K64 19 13952509-13961449 "Predicted intracellular proteins" "Immunity, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 13.7;Bergmann glia: 15.4;Brain excitatory neurons: 14.2;Brain inhibitory neurons: 8.6;Distal convoluted tubule cells: 8.0;Ependymal cells: 9.3;Loop of henle epithelial cells: 8.3;Microglia: 19.4;Oligodendrocyte progenitor cells: 11.7;Oligodendrocytes: 7.6;Other brain neurons: 9.4;Papillary tip epithelial cells: 10.6;Podocytes: 8.3;Renal collecting duct intercalated cells: 7.8;Renal collecting duct principal cells: 11.2;Renal connecting tubule cells: 9.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068351 Approved Vesicles,Mitochondria NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 67: Testis - Mixed function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 102: Non-specific - Mixed function" 9 Mitochondria Vesicles "HPA068351: " "unprognostic (2.36e-2)" "unprognostic (5.62e-2)" "unprognostic (1.82e-1)" "unprognostic (9.27e-2)" "unprognostic (1.19e-1)" "unprognostic (2.31e-2)" "unprognostic (5.90e-2)" "unprognostic (1.45e-1)" "unprognostic (1.38e-1)" "unprognostic (1.28e-2)" "unprognostic (2.89e-3)" "unprognostic (8.24e-2)" "unprognostic (6.43e-2)" "unprognostic (1.12e-3)" "unprognostic (1.87e-1)" "unprognostic (1.68e-1)" "unprognostic (9.88e-2)" "unprognostic (1.28e-1)" "unprognostic (1.19e-2)" "unprognostic (8.07e-2)" "unprognostic (3.37e-1)" "unprognostic (1.50e-1)" "unprognostic (8.62e-3)" "unprognostic (1.01e-1)" "unprognostic (1.57e-1)" "unprognostic (2.47e-2)" "unprognostic (1.41e-1)" "unprognostic (9.43e-2)" "unprognostic (6.58e-2)" "unprognostic (5.36e-2)" "unprognostic (1.56e-1)" DCAF16 "C4orf30, FLJ20280" ENSG00000163257 "DDB1 and CUL4 associated factor 16" Q9NXF7 4 17800655-17810758 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042487 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 54: Non-specific - Ribosome" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 7: Non-specific - Transcription" 12 "Plasma membrane, Cytosol" "HPA042487: " "unprognostic (3.00e-3)" "unprognostic (1.30e-1)" "unprognostic (1.74e-2)" "unprognostic (1.11e-1)" "unprognostic (9.63e-2)" "unprognostic (2.14e-1)" "unprognostic (1.18e-1)" "unprognostic (2.05e-3)" "unprognostic (1.44e-1)" "unprognostic (8.80e-3)" "unprognostic (1.03e-2)" "potential prognostic favorable (5.76e-4)" "unprognostic (1.70e-1)" "potential prognostic unfavorable (4.15e-4)" "unprognostic (2.09e-2)" "unprognostic (3.20e-2)" "unprognostic (1.25e-1)" "unprognostic (9.94e-2)" "unprognostic (5.07e-3)" "unprognostic (1.30e-1)" "unprognostic (1.16e-1)" "unprognostic (6.85e-2)" "unprognostic (1.10e-1)" "unprognostic (1.16e-1)" "unprognostic (3.42e-3)" "unprognostic (4.98e-3)" "unprognostic (1.28e-1)" "unprognostic (1.46e-1)" "unprognostic (1.57e-1)" "unprognostic (2.93e-2)" "unprognostic (1.82e-2)" DCAF17 "C2orf37, FLJ13096" ENSG00000115827 "DDB1 and CUL4 associated factor 17" Q5H9S7 2 171434217-171485052 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Deafness, Diabetes mellitus, Hypotrichosis, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 64.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053339, HPA055040" Uncertain Supported Nucleoplasm NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 61: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 7: Non-specific - Transcription" 5 Nucleoplasm "HPA053339: , HPA055040: " "unprognostic (1.95e-2)" "unprognostic (5.53e-3)" "unprognostic (2.16e-1)" "unprognostic (6.99e-3)" "unprognostic (3.11e-2)" "unprognostic (1.93e-1)" "unprognostic (1.42e-1)" "unprognostic (2.08e-1)" "unprognostic (3.99e-2)" "unprognostic (1.72e-2)" "unprognostic (7.87e-3)" "unprognostic (8.49e-3)" "unprognostic (4.35e-1)" "unprognostic (1.76e-2)" "unprognostic (2.46e-1)" "unprognostic (3.49e-2)" "unprognostic (1.69e-2)" "unprognostic (5.76e-2)" "unprognostic (9.90e-2)" "unprognostic (4.70e-2)" "unprognostic (1.06e-2)" "unprognostic (9.28e-2)" "unprognostic (1.04e-3)" "unprognostic (2.22e-1)" "unprognostic (2.18e-1)" "unprognostic (3.22e-1)" "unprognostic (4.75e-2)" "unprognostic (1.99e-1)" "unprognostic (3.06e-1)" "potential prognostic unfavorable (6.74e-4)" "unprognostic (2.18e-1)" DCAF4 "DKFZp434K114, WDR21, WDR21A" ENSG00000119599 "DDB1 and CUL4 associated factor 4" Q8WV16 14 72926377-72959703 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 40.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" HPA047276 Approved Approved Nucleoplasm NA NA "Cluster 18: Non-specific - Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 24: Neurons - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 21 Nucleoplasm "HPA047276: " "unprognostic (1.73e-1)" "unprognostic (1.29e-2)" "unprognostic (3.51e-1)" "unprognostic (2.05e-3)" "unprognostic (3.66e-1)" "unprognostic (2.98e-1)" "unprognostic (1.08e-1)" "unprognostic (4.58e-1)" "unprognostic (3.50e-1)" "unprognostic (1.08e-1)" "unprognostic (9.65e-3)" "unprognostic (2.97e-1)" "unprognostic (9.39e-3)" "potential prognostic unfavorable (1.11e-4)" "unprognostic (1.81e-2)" "unprognostic (1.35e-1)" "unprognostic (8.91e-3)" "unprognostic (4.04e-2)" "unprognostic (3.45e-1)" "unprognostic (1.84e-2)" "unprognostic (6.64e-3)" "unprognostic (3.57e-1)" "unprognostic (9.11e-2)" "unprognostic (1.94e-1)" "unprognostic (6.27e-3)" "potential prognostic unfavorable (4.67e-4)" "unprognostic (1.43e-1)" "unprognostic (1.81e-1)" "unprognostic (1.99e-1)" "unprognostic (9.06e-2)" "unprognostic (1.61e-1)" DCAF4L1 WDR21B ENSG00000182308 "DDB1 and CUL4 associated factor 4 like 1" Q3SXM0 4 41981756-41986465 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "testis: 23.1" "Group enriched" "Detected in some" 5 "Differentiating spermatogonia: 99.2;Early primary spermatocytes: 90.7;Late primary spermatocytes: 46.1;Undifferentiated spermatogonia: 179.0" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in single" 41 "Testicular Germ Cell Tumor (TCGA): 12.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pituitary gland - Somatotropes, Testis - Spermatogonia" CAB073535 Enhanced Supported Nucleoli,Cytosol NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 17 Cytosol Nucleoli "CAB073535: " "unprognostic (3.70e-1)" "unprognostic (1.25e-1)" "unprognostic (3.42e-1)" DCAF4L2 WDR21C ENSG00000176566 "DDB1 and CUL4 associated factor 4 like 2" Q8NA75 8 87870747-87874015 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 200 "testis: 19.9" "Group enriched" "Detected in some" 6 "Differentiating spermatogonia: 81.2;Early primary spermatocytes: 69.4;Late primary spermatocytes: 41.0;Oocytes: 23.0;Undifferentiated spermatogonia: 71.2" "Group enriched" "Detected in some" 21 "committed oligodendrocyte precursor: 4.4;oligodendrocyte precursor cell: 2.4" "Cancer enriched" "Detected in some" 7 "Testicular Germ Cell Tumor (TCGA): 30.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 5.3;liver cancer: 4.1;Myeloma: 7.5" "Testis - Spermatocytes, Testis - Spermatogonia" HPA067584 Uncertain NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 17 "HPA067584: " "unprognostic (7.71e-2)" "unprognostic (4.43e-2)" "unprognostic (1.62e-1)" "unprognostic (3.84e-1)" "unprognostic (2.82e-1)" DCAF5 "BCRG2, BCRP2, D14S1461E, KIAA1824, WDR22" ENSG00000139990 "DDB1 and CUL4 associated factor 5" Q96JK2 14 69050881-69153150 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041575, HPA048098" Uncertain Approved Mitochondria NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 39: Testis - Nuclear processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 7: Non-specific - Transcription" 37 Mitochondria "HPA041575: , HPA048098: " "unprognostic (7.45e-2)" "unprognostic (1.34e-1)" "unprognostic (7.84e-2)" "potential prognostic unfavorable (8.66e-4)" "unprognostic (6.73e-2)" "unprognostic (1.35e-2)" "unprognostic (1.45e-1)" "unprognostic (1.35e-2)" "unprognostic (4.05e-1)" "unprognostic (1.53e-2)" "potential prognostic favorable (1.57e-4)" "unprognostic (1.33e-2)" "unprognostic (1.56e-1)" "unprognostic (2.04e-2)" "unprognostic (4.99e-2)" "unprognostic (1.16e-1)" "unprognostic (1.38e-1)" "unprognostic (2.48e-1)" "unprognostic (9.03e-2)" "unprognostic (7.54e-2)" "unprognostic (6.82e-3)" "unprognostic (3.24e-1)" "unprognostic (5.28e-3)" "unprognostic (2.03e-1)" "unprognostic (1.59e-1)" "unprognostic (1.62e-1)" "unprognostic (3.51e-2)" "unprognostic (1.12e-1)" "unprognostic (5.96e-2)" "unprognostic (3.76e-2)" "unprognostic (5.92e-2)" DCAF6 "IQWD1, PC326" ENSG00000143164 "DDB1 and CUL4 associated factor 6" Q58WW2 1 167935783-168075843 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "skeletal muscle: 585.8;tongue: 429.2" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 599.5;Late spermatids: 1105.7;Myonuclei: 592.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA074904, HPA075774" Supported Nucleoplasm,Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 82: Dendritic cells - Antigen presentation" 33 Nucleoplasm Cytosol "HPA074904: , HPA075774: " "unprognostic (2.13e-1)" "unprognostic (3.18e-2)" "unprognostic (8.41e-2)" "unprognostic (4.57e-2)" "unprognostic (7.97e-2)" "unprognostic (3.16e-3)" "unprognostic (1.47e-1)" "unprognostic (1.79e-1)" "unprognostic (5.74e-2)" "unprognostic (2.62e-2)" "potential prognostic favorable (8.80e-6)" "unprognostic (8.23e-2)" "unprognostic (1.96e-1)" "unprognostic (2.36e-1)" "unprognostic (6.75e-2)" "unprognostic (3.04e-1)" "unprognostic (2.96e-1)" "unprognostic (7.03e-2)" "unprognostic (3.62e-1)" "unprognostic (2.15e-1)" "potential prognostic unfavorable (3.86e-4)" "unprognostic (2.30e-2)" "unprognostic (1.50e-1)" "unprognostic (2.78e-1)" "unprognostic (2.15e-1)" "unprognostic (2.88e-1)" "unprognostic (2.50e-1)" "unprognostic (2.35e-2)" "unprognostic (2.16e-1)" "unprognostic (1.29e-1)" "unprognostic (2.86e-1)" DCAF7 "HAN11, SWAN-1, WDR68" ENSG00000136485 "DDB1 and CUL4 associated factor 7" P61962 17 63550222-63594286 "Essential proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 46.3;Bergmann glia: 56.1;Brain excitatory neurons: 59.2;Brain inhibitory neurons: 57.7;Choroid plexus epithelial cells: 79.7;Distal convoluted tubule cells: 78.9;Loop of henle epithelial cells: 72.9;Microglia: 91.9;Oligodendrocyte progenitor cells: 61.0;Oligodendrocytes: 66.1;Other brain neurons: 52.5;Papillary tip epithelial cells: 66.6;Podocytes: 69.2;Proximal tubule cells: 89.3;Renal collecting duct intercalated cells: 82.6;Renal collecting duct principal cells: 75.6;Renal connecting tubule cells: 76.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022948, HPA022962" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 7: Non-specific - Ribosome" "Cluster 27: Breast cancer - Unknown function" "Cluster 102: Non-specific - Mixed function" 186 Nucleoplasm Cytosol "HPA022948: , HPA022962: " "unprognostic (2.21e-3)" "unprognostic (4.99e-2)" "unprognostic (1.45e-1)" "unprognostic (7.45e-3)" "unprognostic (8.29e-3)" "unprognostic (1.36e-1)" "unprognostic (1.06e-1)" "unprognostic (1.17e-1)" "unprognostic (1.46e-1)" "unprognostic (3.87e-3)" "validated prognostic favorable (2.45e-6)" "validated prognostic favorable (5.18e-4)" "unprognostic (1.93e-1)" "unprognostic (1.11e-3)" "unprognostic (1.38e-3)" "unprognostic (7.77e-3)" "unprognostic (1.20e-2)" "unprognostic (1.27e-1)" "unprognostic (9.75e-3)" "unprognostic (1.20e-1)" "unprognostic (4.61e-1)" "unprognostic (7.56e-2)" "unprognostic (2.47e-1)" "unprognostic (8.90e-2)" "unprognostic (1.26e-1)" "unprognostic (6.61e-2)" "unprognostic (8.20e-2)" "unprognostic (8.62e-2)" "unprognostic (1.35e-1)" "unprognostic (8.30e-2)" "unprognostic (1.73e-1)" DCAF8 "FLJ35857, H326, WDR42A" ENSG00000132716 "DDB1 and CUL4 associated factor 8" Q5TAQ9 1 160215715-160262549 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 75.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027218, HPA027381" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 45: Non-specific - Nuclear processes" "Cluster 22: Non-specific - Basic cellular functions" 46 Nucleoplasm Cytosol "HPA027218: , HPA027381: " "unprognostic (2.65e-2)" "unprognostic (9.12e-2)" "unprognostic (1.78e-1)" "unprognostic (8.44e-3)" "unprognostic (1.16e-1)" "unprognostic (1.64e-2)" "unprognostic (1.50e-1)" "unprognostic (2.08e-2)" "unprognostic (9.50e-3)" "unprognostic (2.36e-2)" "validated prognostic favorable (4.93e-5)" "validated prognostic favorable (7.22e-5)" "unprognostic (1.58e-1)" "unprognostic (1.54e-1)" "potential prognostic favorable (2.33e-4)" "unprognostic (8.33e-2)" "unprognostic (1.51e-1)" "unprognostic (6.96e-2)" "unprognostic (2.66e-2)" "unprognostic (1.40e-1)" "unprognostic (3.94e-2)" "unprognostic (8.56e-2)" "unprognostic (6.13e-2)" "unprognostic (2.33e-1)" "unprognostic (3.33e-2)" "unprognostic (2.95e-2)" "unprognostic (1.34e-1)" "unprognostic (2.22e-1)" "unprognostic (1.47e-1)" "unprognostic (4.15e-2)" "unprognostic (6.09e-2)" DCAF8L1 WDR42B ENSG00000226372 "DDB1 and CUL4 associated factor 8 like 1" A6NGE4 X 27977992-27981449 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "Differentiating spermatogonia: 6.0;Early primary spermatocytes: 11.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Spermatocytes, Testis - Spermatogonia" HPA043787 Enhanced NA NA "Cluster 51: Myeloma - Immunoglobulins" "Cluster 3: Early primary spermatocytes - Early meiosis" 1 "HPA043787: " DCAF8L2 WDR42C ENSG00000189186 "DDB1 and CUL4 associated factor 8 like 2" P0C7V8 X 27590344-27749942 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 25 "testis: 18.6" "Cell type enriched" "Detected in some" 26 "Sertoli cells: 1306.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 1.5;Rhabdoid: 2.0" "Testis - Sertoli cells" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 9 DCAKD FLJ22955 ENSG00000172992 "Dephospho-CoA kinase domain containing" Q8WVC6 17 45023338-45061131 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060997 Approved Nucleoplasm NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 73: Brain - Neuronal signaling" "Cluster 44: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 100: Stratified epithelial cells - Barrier functions" 16 Nucleoplasm "HPA060997: " "unprognostic (1.91e-2)" "unprognostic (1.59e-1)" "unprognostic (5.02e-2)" "unprognostic (1.75e-1)" "unprognostic (1.13e-1)" "unprognostic (8.95e-2)" "unprognostic (3.10e-1)" "unprognostic (1.49e-2)" "unprognostic (2.26e-2)" "unprognostic (4.20e-2)" "unprognostic (2.48e-1)" "unprognostic (1.88e-1)" "potential prognostic favorable (7.24e-4)" "unprognostic (2.35e-2)" "unprognostic (4.79e-2)" "unprognostic (6.18e-2)" "unprognostic (2.36e-1)" "unprognostic (4.31e-2)" "unprognostic (2.95e-2)" "unprognostic (3.09e-1)" "unprognostic (9.71e-2)" "unprognostic (1.01e-2)" "unprognostic (1.63e-1)" "unprognostic (1.08e-2)" "unprognostic (1.14e-3)" "unprognostic (9.49e-3)" "unprognostic (2.20e-2)" "unprognostic (7.71e-2)" "unprognostic (7.84e-2)" "unprognostic (4.50e-2)" "unprognostic (8.65e-3)" DCANP1 "C5orf20, DCNP1" ENSG00000251380 "Dendritic cell associated nuclear protein 1" Q8TF63 5 135444214-135447348 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "pDCs: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA048308 Uncertain Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 6 Nucleoplasm "Nuclear bodies" "HPA048308: " DCBLD1 "dJ94G16.1, MGC46341" ENSG00000164465 "Discoidin, CUB and LCCL domain containing 1" Q8N8Z6 6 117453817-117569858 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Gonadotrophs: 79.0;Pericytes: 121.4" "Cell type enhanced" "Detected in all" "endothelial cell: 88.9;pericyte: 105.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA059667 Approved Approved Cytosol NA NA 2500000 "Cluster 11: T-cells - Unknown function" "Cluster 60: Stomach - Digestion" "Cluster 53: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 110: Mural cells - ECM organization" 1 Cytosol "HPA059667: " "unprognostic (4.95e-2)" "unprognostic (8.67e-2)" "unprognostic (3.03e-1)" "unprognostic (4.76e-3)" "unprognostic (4.34e-2)" "unprognostic (1.30e-1)" "unprognostic (2.25e-1)" "unprognostic (3.10e-1)" "unprognostic (3.80e-3)" "potential prognostic unfavorable (6.81e-4)" "unprognostic (2.60e-1)" "unprognostic (5.10e-2)" "unprognostic (2.17e-2)" "unprognostic (1.23e-2)" "unprognostic (2.08e-1)" "unprognostic (1.04e-1)" "unprognostic (1.61e-2)" "potential prognostic unfavorable (6.30e-4)" "unprognostic (8.91e-3)" "unprognostic (2.22e-1)" "potential prognostic unfavorable (5.00e-4)" "unprognostic (2.27e-3)" "potential prognostic unfavorable (3.44e-4)" "unprognostic (6.65e-2)" "unprognostic (1.95e-1)" "unprognostic (1.12e-2)" "unprognostic (8.17e-2)" "unprognostic (2.36e-2)" "unprognostic (1.21e-1)" "unprognostic (5.71e-2)" "unprognostic (3.57e-1)" DCBLD2 "CLCP1, ESDN" ENSG00000057019 "Discoidin, CUB and LCCL domain containing 2" Q96PD2 3 98795941-98901695 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bergmann glia: 222.0;Podocytes: 218.6;Sertoli cells: 478.7" "Cell type enhanced" "Detected in all" "Bergmann glia: 267.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Smooth muscle cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016909 Approved Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA 1000000 "Cluster 61: Non-specific - Transcription" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 72: Neuronal - Signal transduction" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 1 "Plasma membrane, Cytosol" "Golgi apparatus" "HPA016909: " "unprognostic (1.31e-1)" "unprognostic (1.11e-1)" "unprognostic (1.32e-1)" "unprognostic (3.15e-1)" "unprognostic (8.91e-3)" "unprognostic (1.63e-1)" "unprognostic (1.70e-2)" "unprognostic (1.30e-1)" "unprognostic (5.53e-2)" "potential prognostic unfavorable (7.24e-4)" "validated prognostic unfavorable (5.13e-4)" "validated prognostic unfavorable (3.26e-4)" "unprognostic (4.20e-2)" "unprognostic (4.02e-3)" "potential prognostic unfavorable (1.02e-4)" "potential prognostic unfavorable (3.93e-4)" "unprognostic (1.11e-2)" "unprognostic (6.35e-2)" "unprognostic (2.13e-1)" "unprognostic (1.84e-1)" "unprognostic (1.15e-2)" "validated prognostic unfavorable (4.98e-4)" "validated prognostic unfavorable (1.81e-5)" "unprognostic (2.30e-1)" "unprognostic (3.51e-1)" "unprognostic (9.91e-2)" "unprognostic (1.17e-1)" "potential prognostic unfavorable (5.29e-4)" "unprognostic (2.35e-1)" "unprognostic (2.51e-1)" "unprognostic (5.28e-2)" DCC "IGDCC1, NTN1R1" ENSG00000187323 "DCC netrin 1 receptor" P43146 18 52340197-53535903 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Developmental protein, Receptor" "Cancer-related genes, Disease variant, Intellectual disability, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.0;testis: 7.2" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 744.0;Brain inhibitory neurons: 1141.3;Corticotrophs: 2012.7;Early spermatids: 414.9;Late spermatids: 291.7;Oligodendrocyte progenitor cells: 1894.5;Other brain neurons: 646.5;Plasma cells: 382.2;Retinal amacrine cells: 543.0;Thyrotrophs: 568.4" "Cell type enhanced" "Detected in all" "hippocampal CA4: 3187.4" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 2.1;Lung Squamous Cell Carcinoma (TCGA): 1.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Bone cancer: 6.9;Myeloma: 23.2" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Plasma cells, Spleen - Plasma cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Plasma cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA055376, HPA069552" Enhanced Approved "Golgi apparatus,Centriolar satellite,Centrosome,Basal body" NA NA 35000 "Cluster 67: Testis - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 20: Myeloma - Immune response" "Cluster 35: Neurons - Synaptic function & neurogenesis" 39 "Golgi apparatus" "Centriolar satellite, Centrosome, Basal body" "HPA055376: , HPA069552: " "unprognostic (5.96e-3)" "unprognostic (4.28e-2)" "unprognostic (2.76e-1)" "unprognostic (4.47e-3)" DCD "AIDD, DCD-1, DSEP, HCAP, PIF" ENSG00000161634 Dermcidin P81605 12 54644589-54648493 "Plasma proteins, Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial, Fungicide, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "skin 1: 3313.5" "Cell type enriched" "Detected in some" 76 "Smooth muscle cells: 114.3" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 9 "Breast Invasive Carcinoma (TCGA): 332.5" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 5 "Bone cancer: 1.0;breast cancer: 3.9" "Skin - Eccrine sweat gland cells" HPA063967 Enhanced "Secreted in other tissues" Enzyme NA NA 200000000 "Cluster 15: NK-cells - Unknown function" "Cluster 9: Skin - Hair follicle development" "Cluster 9: Non-specific - Receptor signaling" "Cluster 27: Breast cancer - Unknown function" "Cluster 62: Smooth muscle cells - Muscle contraction" 15 "HPA063967: " "unprognostic (8.31e-3)" "unprognostic (9.44e-2)" "unprognostic (4.61e-1)" "unprognostic (1.80e-1)" "unprognostic (1.02e-1)" DCDC1 "DCDC5, FLJ46154" ENSG00000170959 "Doublecortin domain containing 1" M0R2J8 11 30830369-31369810 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 2.6;fallopian tube: 2.7;liver: 2.6;retina: 2.7" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 751.7;Endometrial ciliated cells: 582.3;Ependymal cells: 1942.2;Epididymal efferent duct ciliated cells: 377.7;Fallopian tube ciliated cells: 549.1;Respiratory ciliated cells: 1301.0;Retinal ganglion cells: 861.4;Somatotrophs: 293.0;Thyrotrophs: 297.5" "Group enriched" "Detected in all" 8 "choroid plexus epithelial cell: 630.8;ependymal cell: 2099.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Pituitary gland - Somatotropes, Testis - Early spermatids" "Low region specificity" "Detected in all" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" "unprognostic (4.81e-2)" "unprognostic (1.40e-1)" "unprognostic (1.01e-1)" "unprognostic (3.87e-1)" "unprognostic (2.78e-1)" "unprognostic (2.79e-3)" DCDC2 "DCDC2A, DFNB66, KIAA1154, NPHP19, RU2" ENSG00000146038 "Doublecortin domain containing 2" Q9UHG0 6 24171755-24358059 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation, Neurogenesis" "Ciliopathy, Deafness, Disease variant, Nephronophthisis, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 19.5;kidney: 20.4;pancreas: 24.9" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 391.8;Distal convoluted tubule cells: 1047.2;Endometrial ciliated cells: 820.7;Endometrial glandular cells: 606.1;Endometrial luminal cells: 365.8;Ependymal cells: 369.9;Epididymal efferent duct absorptive cells: 796.2;Epididymal efferent duct ciliated cells: 781.1;Loop of henle epithelial cells: 373.0;Pancreatic duct cells: 574.2;Proximal tubule cells: 415.6;Renal collecting duct principal cells: 385.0;Renal connecting tubule cells: 1441.3" "Group enriched" "Detected in many" 10 "choroid plexus epithelial cell: 384.7;ependymal cell: 400.5" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 36.9" "Region enriched" "Detected in all" 5 "choroid plexus: 33.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 45.3;ovarian cancer: 38.7" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Pancreas - Ductal cells, Stomach - Parietal cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA031582, HPA031583, HPA031584" Enhanced Approved "Microtubules,Mitotic spindle,Centriolar satellite,Cytosol,Acrosome,Equatorial segment,Principal piece" Yes NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 17: Choroid plexus - Cilium" "Cluster 15: Kidney cancer - Membrane components" "Cluster 51: Secretory epithelial cells - Mixed function" 26 "Microtubules, Cytosol" "Mitotic spindle, Centriolar satellite, Acrosome, Equatorial segment, Principal piece" "HPA031582: , HPA031583: , HPA031584: " "unprognostic (1.27e-2)" "unprognostic (2.85e-2)" "unprognostic (2.43e-2)" "unprognostic (2.93e-2)" "unprognostic (5.12e-1)" "unprognostic (1.09e-1)" "unprognostic (1.19e-3)" "unprognostic (6.36e-3)" "unprognostic (2.04e-2)" "unprognostic (2.93e-3)" "unprognostic (9.69e-3)" "unprognostic (1.03e-1)" "unprognostic (8.42e-2)" "unprognostic (2.33e-1)" "unprognostic (2.05e-3)" "unprognostic (1.45e-1)" "unprognostic (5.55e-2)" "unprognostic (7.25e-2)" "unprognostic (1.49e-1)" "unprognostic (6.88e-2)" "unprognostic (5.39e-2)" "unprognostic (3.71e-1)" "unprognostic (2.19e-1)" "unprognostic (3.63e-2)" "unprognostic (5.90e-2)" "unprognostic (1.53e-1)" "unprognostic (2.12e-1)" DCDC2B ENSG00000222046 "Doublecortin domain containing 2B" A2VCK2 1 32209089-32216192 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "fallopian tube: 26.0" "Group enriched" "Detected in many" 4 "Endometrial ciliated cells: 40.8;Epididymal efferent duct ciliated cells: 85.2;Fallopian tube ciliated cells: 148.5;Respiratory ciliated cells: 152.0" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in some" 5 "Lung Adenocarcinoma (TCGA): 1.0;Uterine Corpus Endometrial Carcinoma (TCGA): 3.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA045832 Uncertain NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" 10 "HPA045832: " "unprognostic (1.22e-2)" "unprognostic (5.23e-3)" "unprognostic (2.68e-1)" DCDC2C ENSG00000214866 "Doublecortin domain containing 2C" A8MYV0 2 3703575-3848008 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 1.2;testis: 3.0" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 48.6;Early spermatids: 331.2;Late spermatids: 103.8;Leydig cells: 39.2;Lymphatic endothelial cells: 36.2;Medullary thymic epithelial cells: 26.4;Oocytes: 46.1;Peritubular myoid cells: 112.5;Pituitary stem cells: 52.3;Podocytes: 31.5" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 46.7;fibroblast: 90.0;medium spiny neuron: 52.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids, Thyroid gland - Fibroblasts" "Not detected" "Not detected" "Not detected" "Not detected" HPA045848 Uncertain Supported "End piece" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 32: Non-specific - Cell proliferation" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" "End piece" "HPA045848: " "unprognostic (1.64e-2)" "unprognostic (3.82e-2)" DCHS1 "CDH25, CDHR6, FIB1, FLJ11790, KIAA1773, PCDH16" ENSG00000166341 "Dachsous cadherin-related 1" Q96JQ0 11 6621330-6655809 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Deafness, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 15.7;Bergmann glia: 32.0;Decidual stromal cells: 15.8;Endometrial stromal cells: 19.3;Fibroblasts: 14.8;Granulosa cells: 12.2;Lymphatic endothelial cells: 25.4;Melanocytes: 15.1;Oligodendrocyte progenitor cells: 14.6;Ovarian stromal cells: 11.0;Pituicytes/FSCs: 14.8;Smooth muscle cells: 15.2;Vascular endothelial cells: 30.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 12.8;Neuroblastoma: 28.7" "Kidney - Endothelial cells, Lung - Endothelial cells, Minor Salivary Gland - Endothelial cells, Skeletal muscle - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017970, HPA050246" Approved Approved "Plasma membrane" NA NA 12000000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 1 "Plasma membrane" "HPA017970: , HPA050246: " "potential prognostic favorable (5.08e-4)" "unprognostic (2.56e-1)" "unprognostic (1.27e-1)" "unprognostic (6.83e-2)" "unprognostic (1.37e-2)" "unprognostic (2.38e-1)" "unprognostic (1.64e-1)" "unprognostic (1.78e-1)" "unprognostic (5.80e-3)" "unprognostic (1.12e-1)" "potential prognostic favorable (6.05e-4)" "unprognostic (6.09e-3)" "unprognostic (1.97e-2)" "unprognostic (1.51e-2)" "potential prognostic favorable (5.40e-4)" "unprognostic (1.26e-1)" "unprognostic (2.49e-2)" "unprognostic (9.09e-3)" "unprognostic (2.15e-1)" "unprognostic (6.22e-2)" "unprognostic (3.20e-1)" "unprognostic (6.10e-2)" "unprognostic (3.25e-1)" "unprognostic (2.97e-2)" "unprognostic (2.04e-1)" "unprognostic (5.95e-3)" "unprognostic (1.02e-2)" "unprognostic (6.36e-2)" "unprognostic (1.94e-1)" "unprognostic (1.93e-2)" "unprognostic (7.45e-2)" DCHS2 "CDH27, CDHJ, CDHR7, FLJ20047, PCDH23, PCDHJ" ENSG00000197410 "Dachsous cadherin-related 2" Q6V1P9 4 154231742-154491799 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.5;endometrium 1: 1.1;intestine: 1.0" "Cell type enhanced" "Detected in some" "Astrocytes: 115.2;Brain excitatory neurons: 26.8;Brain inhibitory neurons: 45.0;Ependymal cells: 13.8;Other brain neurons: 56.3" "Cell type enhanced" "Detected in all" "deep-layer corticothalamic and 6b: 181.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adrenal gland - Adrenal medulla cells, Kidney - Fibroblasts, Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA064159 Uncertain Approved "Vesicles,Plasma membrane" NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 14: Neurons - Synaptic function" "Cluster 40: Non-specific - Unknown function" "Cluster 28: Astrocytes - Homeostasis & neuron support" "Vesicles, Plasma membrane" "HPA064159: " "unprognostic (2.47e-1)" "unprognostic (3.81e-2)" "unprognostic (2.75e-2)" DCK ENSG00000156136 "Deoxycytidine kinase" P27707 4 70992538-71030914 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 98.5" "Cell type enhanced" "Detected in many" "B-cells: 66.1;Early primary spermatocytes: 66.3;Erythrocyte progenitors: 82.3;Kupffer cells: 85.1;Monocyte progenitors: 94.4;pDCs: 148.8;Platelets: 79.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "lymphoma: 102.1" "Low region specificity" "Detected in all" "HPA059609, HPA062773" Enhanced Supported Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 15 Nucleoplasm "HPA059609: , HPA062773: " "unprognostic (1.04e-1)" "unprognostic (1.89e-2)" "unprognostic (1.01e-1)" "unprognostic (1.05e-1)" "unprognostic (7.45e-3)" "unprognostic (1.93e-1)" "unprognostic (3.09e-1)" "unprognostic (1.29e-2)" "unprognostic (5.88e-2)" "potential prognostic unfavorable (5.35e-5)" "potential prognostic favorable (2.42e-8)" "unprognostic (1.95e-1)" "unprognostic (1.19e-1)" "potential prognostic unfavorable (1.29e-6)" "unprognostic (1.52e-2)" "potential prognostic unfavorable (9.80e-4)" "unprognostic (3.78e-2)" "unprognostic (2.32e-2)" "unprognostic (7.68e-2)" "unprognostic (1.25e-1)" "unprognostic (2.17e-2)" "unprognostic (1.76e-1)" "unprognostic (6.14e-3)" "unprognostic (1.77e-2)" "unprognostic (1.02e-1)" "unprognostic (1.97e-1)" "unprognostic (5.26e-2)" "unprognostic (1.19e-2)" "unprognostic (1.59e-1)" "unprognostic (3.13e-1)" "unprognostic (1.97e-1)" DCLK1 "DCAMKL1, DCDC3A, DCLK, KIAA0369" ENSG00000133083 "Doublecortin like kinase 1" O15075 13 35768652-36131382 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 93.3" "Cell type enhanced" "Detected in many" "Astrocytes: 537.6;Brain excitatory neurons: 755.7;Brain inhibitory neurons: 670.9;Corticotrophs: 1061.1;Ependymal cells: 323.8;Fibro-adipogenic progenitors: 1305.8;Fibroblasts: 603.2;Müller glia: 484.6;Other brain neurons: 695.6;Pituicytes/FSCs: 844.1;Retinal amacrine cells: 339.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 24.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Rhabdoid: 104.6" "Breast - Fibroblasts, Lung - Fibroblasts_2, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012405, HPA015040, HPA015655" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 108: Fibroblasts - ECM organization" 2 Nucleoplasm Cytosol "CAB012405: , HPA015040: , HPA015655: " "unprognostic (2.54e-2)" "unprognostic (1.12e-1)" "unprognostic (2.43e-1)" "unprognostic (1.07e-1)" "unprognostic (1.75e-1)" "unprognostic (1.10e-1)" "unprognostic (1.58e-1)" "unprognostic (2.27e-3)" "unprognostic (5.53e-3)" "unprognostic (4.76e-1)" "unprognostic (3.93e-2)" "unprognostic (4.73e-2)" "unprognostic (1.28e-1)" "unprognostic (1.19e-1)" "unprognostic (2.62e-1)" "unprognostic (7.04e-2)" "unprognostic (7.10e-2)" "unprognostic (1.54e-1)" "unprognostic (6.95e-2)" "unprognostic (1.98e-1)" "unprognostic (4.67e-3)" "unprognostic (1.26e-1)" "unprognostic (1.66e-1)" "unprognostic (2.02e-1)" DCLK2 "DCAMKL2, DCDC3, DCDC3B, DCK2, MGC45428" ENSG00000170390 "Doublecortin like kinase 2" Q8N568 4 150078445-150257438 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 45.8;retina: 17.1" "Cell type enhanced" "Detected in many" "Astrocytes: 1117.2;Bergmann glia: 843.0;Brain excitatory neurons: 232.5;Brain inhibitory neurons: 282.1;Ependymal cells: 418.3;Oligodendrocyte progenitor cells: 288.9;Other brain neurons: 229.3;Retinal amacrine cells: 267.0;Tuft cells: 426.5" "Cell type enhanced" "Detected in all" "astrocyte: 1768.4" "Cancer enriched" "Detected in many" 9 "Glioblastoma Multiforme (TCGA): 79.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 10.8" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015770 Enhanced Approved NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 29: Forebrain - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 28: Astrocytes - Homeostasis & neuron support" 2 "HPA015770: " "unprognostic (1.14e-2)" "unprognostic (5.53e-2)" "unprognostic (2.40e-1)" "unprognostic (2.88e-1)" "unprognostic (2.75e-1)" "unprognostic (2.19e-2)" "unprognostic (1.03e-1)" "unprognostic (1.70e-3)" "unprognostic (7.12e-3)" "potential prognostic favorable (1.98e-5)" "unprognostic (2.81e-3)" "unprognostic (1.45e-2)" "unprognostic (3.07e-2)" "unprognostic (7.47e-3)" "unprognostic (1.71e-2)" "potential prognostic favorable (7.10e-5)" "unprognostic (1.04e-1)" "unprognostic (4.56e-2)" "unprognostic (2.01e-1)" "unprognostic (1.59e-1)" "unprognostic (1.37e-2)" "unprognostic (2.88e-2)" "unprognostic (1.09e-1)" "unprognostic (2.80e-2)" DCLK3 "DCAMKL3, DCDC3C, KIAA1765" ENSG00000163673 "Doublecortin like kinase 3" Q9C098 3 36712421-36764553 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.8;testis: 2.6" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 21.3;Brain inhibitory neurons: 16.3;Cone photoreceptor cells: 10.4;Corticotrophs: 24.6;Early spermatids: 31.9;Lactotrophs: 14.6;Late primary spermatocytes: 60.6;Retinal amacrine cells: 20.9;Somatotrophs: 23.1;Thyrotrophs: 47.9" "Cell type enhanced" "Detected in many" "eccentric medium spiny neuron: 45.7;medium spiny neuron: 38.4" "Cancer enriched" "Detected in single" 5 "Testicular Germ Cell Tumor (TCGA): 1.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Neuroblastoma: 1.4" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA040685, HPA053234" Approved Approved Vesicles,Cytosol NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" 1 Cytosol Vesicles "HPA040685: , HPA053234: " "unprognostic (3.24e-1)" "unprognostic (4.64e-2)" "unprognostic (6.82e-2)" DCLRE1A "hSNM1, KIAA0086, PSO2, SNM1" ENSG00000198924 "DNA cross-link repair 1A" Q6PJP8 10 113834725-113854383 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Mitosis" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Erythrocyte progenitors: 21.3;Megakaryocytes: 80.4;Platelets: 66.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036907 Approved Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 47: Platelets - Hemostasis" 6 Nucleoplasm "Nucleoli fibrillar center" "HPA036907: " "unprognostic (4.58e-1)" "unprognostic (3.42e-1)" "unprognostic (7.26e-2)" "unprognostic (2.05e-1)" "unprognostic (2.27e-1)" "unprognostic (2.93e-1)" "unprognostic (2.98e-2)" "potential prognostic favorable (8.22e-4)" "unprognostic (5.65e-2)" "unprognostic (2.14e-1)" "potential prognostic favorable (1.07e-5)" "unprognostic (9.44e-2)" "unprognostic (2.14e-1)" "potential prognostic unfavorable (4.95e-4)" "unprognostic (1.34e-1)" "unprognostic (1.50e-3)" "unprognostic (2.97e-1)" "unprognostic (1.62e-1)" "unprognostic (1.45e-1)" "unprognostic (2.59e-1)" "unprognostic (3.61e-1)" "unprognostic (2.07e-1)" "unprognostic (1.75e-1)" "unprognostic (5.80e-2)" "unprognostic (2.56e-3)" "unprognostic (1.57e-1)" "unprognostic (8.84e-2)" "unprognostic (8.60e-2)" "unprognostic (4.46e-1)" "unprognostic (2.62e-1)" "unprognostic (2.98e-1)" DCLRE1B "APOLLO, FLJ12810, FLJ13998, SNM1B" ENSG00000118655 "DNA cross-link repair 1B" Q9H816 1 113904619-113914086 "Disease related genes, Enzymes, Essential proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "Exonuclease, Hydrolase, Nuclease" "Disease variant, Dyskeratosis congenita" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 13.9;Cardiomyocytes: 44.5;Erythrocyte progenitors: 20.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Macrophages, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064934 Supported "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 16 "Nucleoplasm, Nuclear bodies" "HPA064934: " "potential prognostic unfavorable (1.28e-4)" "unprognostic (3.13e-1)" "unprognostic (1.09e-1)" "unprognostic (2.35e-1)" "unprognostic (7.03e-3)" "unprognostic (8.07e-2)" "unprognostic (2.29e-1)" "unprognostic (9.11e-3)" "unprognostic (3.55e-3)" "unprognostic (3.03e-2)" "unprognostic (7.14e-3)" "unprognostic (1.48e-1)" "unprognostic (1.22e-1)" "validated prognostic unfavorable (1.47e-4)" "validated prognostic unfavorable (5.41e-4)" "unprognostic (9.57e-3)" "unprognostic (2.62e-3)" "unprognostic (7.94e-2)" "unprognostic (3.18e-2)" "unprognostic (7.39e-2)" "unprognostic (3.17e-1)" "unprognostic (2.19e-2)" "unprognostic (1.80e-1)" "unprognostic (9.13e-2)" "unprognostic (6.10e-3)" "unprognostic (5.70e-2)" "unprognostic (2.25e-2)" "unprognostic (1.09e-3)" "unprognostic (1.48e-1)" "unprognostic (9.91e-2)" "unprognostic (6.95e-2)" DCLRE1C "A-SCID, ARTEMIS, FLJ11360, SCIDA, SNM1C" ENSG00000152457 "DNA cross-link repair 1C" Q96SD1 10 14897359-14954432 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Adaptive immunity, DNA damage, DNA recombination, DNA repair, Immunity" "Endonuclease, Exonuclease, Hydrolase, Nuclease" "Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Urothelial cells: 154.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069295 Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 2: Neurons - Nucleosome" "Cluster 52: Non-specific - Mitochondria" "Cluster 69: Urothelial cells - Basic cellular functions" 17 Nucleoplasm "Golgi apparatus" "HPA069295: " "unprognostic (1.06e-1)" "unprognostic (8.49e-2)" "unprognostic (1.59e-1)" "unprognostic (1.02e-1)" "unprognostic (9.61e-2)" "unprognostic (7.58e-2)" "unprognostic (1.55e-2)" "potential prognostic favorable (1.86e-4)" "potential prognostic favorable (9.22e-5)" "unprognostic (2.11e-3)" "unprognostic (5.69e-2)" "unprognostic (3.09e-1)" "unprognostic (3.69e-2)" "potential prognostic unfavorable (9.11e-4)" "unprognostic (2.42e-2)" "unprognostic (1.51e-1)" "unprognostic (3.90e-2)" "unprognostic (1.03e-1)" "unprognostic (5.23e-2)" "unprognostic (1.84e-2)" "unprognostic (1.83e-1)" "unprognostic (1.30e-1)" "unprognostic (5.95e-2)" "unprognostic (1.29e-1)" "unprognostic (1.67e-1)" "unprognostic (2.40e-2)" "unprognostic (1.49e-1)" "unprognostic (2.81e-2)" "unprognostic (2.22e-1)" "unprognostic (2.12e-1)" "unprognostic (2.11e-1)" DCN "DSPG2, SLRR1B" ENSG00000011465 Decorin P07585 12 91140484-91183217 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Corneal dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 6126.8;Endometrial stromal cells: 912.5;Fibro-adipogenic progenitors: 1658.6;Fibroblasts: 7858.0;Hepatic stellate cells: 3014.4;Leydig cells: 5152.8;Ovarian stromal cells: 2189.7;Peritubular myoid cells: 1956.0" "Group enriched" "Detected in many" 4 "fibroblast: 1649.3;pericyte: 1333.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "basophil: 24.5" "Lineage enriched" "Detected in single" 35 "granulocytes: 24.5" "Cancer enriched" "Detected in many" 5 "Rhabdoid: 724.2" "Adrenal gland - Fibroblasts, Breast - Fibroblasts, Colon - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Pituitary gland - Fibroblasts, Prostate - Fibroblasts, Skin - Fibroblasts_2, Spleen - Smooth muscle cells, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 8 "spinal cord: 718.9" "HPA003315, CAB017118, HPA064736, CAB068930" Enhanced "Secreted to extracellular matrix" "No annotated function" NA NA 28000000 "Cluster 46: Basophils - Proteolysis" "Cluster 75: Ovary - Mixed function" "Cluster 8: Immune cells - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 6 "CAB017118: , CAB068930: , HPA003315: , HPA064736: " "unprognostic (1.16e-2)" "unprognostic (1.87e-1)" "unprognostic (4.21e-2)" "unprognostic (1.14e-1)" "unprognostic (6.55e-2)" "unprognostic (3.25e-1)" "unprognostic (5.05e-2)" "unprognostic (2.67e-3)" "unprognostic (2.84e-1)" "unprognostic (2.86e-2)" "unprognostic (1.93e-2)" "unprognostic (2.85e-1)" "potential prognostic unfavorable (2.71e-4)" "unprognostic (3.20e-2)" "unprognostic (4.03e-3)" "unprognostic (1.79e-2)" "unprognostic (2.26e-1)" "unprognostic (6.21e-2)" "unprognostic (1.42e-1)" "unprognostic (2.48e-2)" "unprognostic (1.30e-3)" "unprognostic (1.72e-1)" "unprognostic (1.56e-2)" "unprognostic (1.19e-1)" "unprognostic (1.65e-1)" "unprognostic (3.61e-3)" "unprognostic (2.27e-1)" "potential prognostic unfavorable (3.86e-4)" "unprognostic (6.69e-2)" "unprognostic (3.10e-3)" "unprognostic (1.06e-1)" DCP1A "HSA275986, SMAD4IP1, SMIF" ENSG00000272886 "Decapping mRNA 1A" Q9NPI6 3 53283429-53347586 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Nonsense-mediated mRNA decay" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013202 Approved Supported "Cytoplasmic bodies" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 61: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 80 "Cytoplasmic bodies" "HPA013202: " "unprognostic (1.59e-2)" "unprognostic (3.30e-1)" "unprognostic (2.52e-2)" "unprognostic (7.60e-2)" "unprognostic (6.15e-2)" "unprognostic (9.50e-3)" "unprognostic (1.12e-1)" "unprognostic (1.35e-2)" "unprognostic (2.21e-2)" "validated prognostic favorable (8.56e-5)" "validated prognostic favorable (6.29e-5)" "unprognostic (4.60e-2)" "potential prognostic unfavorable (4.84e-4)" "unprognostic (3.39e-2)" "unprognostic (1.02e-1)" "unprognostic (5.95e-3)" "unprognostic (3.63e-3)" "unprognostic (1.33e-1)" "unprognostic (1.64e-1)" "unprognostic (3.61e-1)" "unprognostic (4.72e-2)" "potential prognostic favorable (5.77e-4)" "unprognostic (6.42e-2)" "unprognostic (1.51e-1)" "unprognostic (6.43e-2)" "unprognostic (2.54e-1)" "unprognostic (9.00e-2)" "unprognostic (2.24e-2)" DCP1B FLJ31638 ENSG00000151065 "Decapping mRNA 1B" Q8IZD4 12 1946053-2004535 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Nonsense-mediated mRNA decay" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 55.3;Bergmann glia: 98.6;Brain inhibitory neurons: 39.0;Choroid plexus epithelial cells: 102.0;Distal convoluted tubule cells: 51.3;Early spermatids: 44.2;Ependymal cells: 52.4;Late primary spermatocytes: 34.8;Loop of henle epithelial cells: 40.4;Microglia: 46.6;Oligodendrocyte progenitor cells: 48.0;Oligodendrocytes: 41.1;Podocytes: 47.2;Proximal tubule cells: 41.3;Renal collecting duct intercalated cells: 40.7;Renal connecting tubule cells: 41.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Lineage enriched" "Detected in all" 5 "T-cells: 27.4" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039709 Approved Supported Vesicles,Cytosol NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 74: Non-specific - Signal transduction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 38: Non-specific - Transcription" "Cluster 102: Non-specific - Mixed function" 42 "Vesicles, Cytosol" "HPA039709: " "unprognostic (3.10e-1)" "unprognostic (1.70e-1)" "unprognostic (5.41e-2)" "unprognostic (2.26e-3)" "unprognostic (3.44e-2)" "unprognostic (6.46e-2)" "unprognostic (1.40e-1)" "unprognostic (3.17e-2)" "unprognostic (6.58e-2)" "unprognostic (7.06e-3)" "unprognostic (5.75e-2)" "unprognostic (3.62e-3)" "unprognostic (3.44e-2)" "unprognostic (3.69e-2)" "unprognostic (1.05e-1)" "unprognostic (1.19e-1)" "unprognostic (1.13e-2)" "unprognostic (1.71e-1)" "unprognostic (1.30e-3)" "unprognostic (2.03e-1)" "unprognostic (4.40e-1)" "unprognostic (1.99e-1)" "unprognostic (1.31e-3)" "unprognostic (1.11e-1)" "unprognostic (4.16e-3)" "unprognostic (2.49e-1)" "unprognostic (2.31e-1)" "unprognostic (1.58e-2)" "unprognostic (1.28e-1)" "unprognostic (6.37e-2)" "unprognostic (8.18e-2)" DCP2 NUDT20 ENSG00000172795 "Decapping mRNA 2" Q8IU60 5 112976702-113022195 "Enzymes, Essential proteins, Predicted intracellular proteins" "Nonsense-mediated mRNA decay" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 232.4;Neutrophils: 484.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011677, HPA057676" Approved Approved "Nucleoplasm,Cell Junctions,Cytoplasmic bodies" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 24: Neutrophils - Innate immunity signal integration" 26 "Nucleoplasm, Cytoplasmic bodies" "Cell Junctions" "CAB011677: , HPA057676: " "unprognostic (1.61e-2)" "unprognostic (2.03e-1)" "unprognostic (5.34e-2)" "unprognostic (1.12e-1)" "unprognostic (1.38e-1)" "unprognostic (1.58e-1)" "unprognostic (4.34e-1)" "unprognostic (4.43e-2)" "unprognostic (5.03e-3)" "unprognostic (2.43e-3)" "potential prognostic favorable (5.37e-4)" "unprognostic (6.16e-2)" "unprognostic (1.54e-1)" "unprognostic (1.17e-3)" "unprognostic (4.64e-2)" "unprognostic (2.47e-1)" "unprognostic (3.48e-2)" "unprognostic (5.65e-2)" "unprognostic (4.68e-1)" "unprognostic (1.62e-2)" "unprognostic (1.31e-2)" "unprognostic (1.67e-1)" "unprognostic (2.04e-3)" "unprognostic (2.56e-2)" "unprognostic (6.02e-2)" "unprognostic (2.89e-2)" "unprognostic (2.18e-2)" "unprognostic (6.30e-2)" "unprognostic (3.36e-1)" "unprognostic (3.45e-3)" "unprognostic (2.62e-2)" DCPS "HINT-5, HINT5, HSL1, HSPC015" ENSG00000110063 "Decapping enzyme, scavenger" Q96C86 11 126304060-126350005 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "mRNA processing, mRNA splicing" Hydrolase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 79.5" "Cell type enhanced" "Detected in many" "pDCs: 92.7;Plasma cells: 87.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 78.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 46.6" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039632, HPA058597" Enhanced Supported Nucleoplasm,Cytosol NA NA 490000 "Cluster 13: Non-specific - Mitochondria" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 23: Choroid plexus - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 44: Plasma cells - Antibody production & secretion" 10 Nucleoplasm Cytosol "HPA039632: , HPA058597: " "unprognostic (3.17e-2)" "unprognostic (7.51e-2)" "unprognostic (3.35e-2)" "unprognostic (3.33e-1)" "unprognostic (3.88e-2)" "unprognostic (1.12e-1)" "unprognostic (4.12e-2)" "unprognostic (3.96e-1)" "unprognostic (2.54e-1)" "unprognostic (1.42e-1)" "unprognostic (2.96e-3)" "unprognostic (3.38e-1)" "unprognostic (2.83e-1)" "unprognostic (3.03e-1)" "unprognostic (1.87e-2)" "unprognostic (1.44e-2)" "potential prognostic unfavorable (2.15e-4)" "unprognostic (6.61e-2)" "unprognostic (1.74e-2)" "unprognostic (2.42e-1)" "unprognostic (6.22e-2)" "unprognostic (2.01e-1)" "unprognostic (7.80e-2)" "unprognostic (2.26e-1)" "unprognostic (3.11e-1)" "unprognostic (9.12e-2)" "unprognostic (1.42e-1)" "unprognostic (8.47e-3)" "unprognostic (7.75e-2)" "unprognostic (3.37e-1)" "unprognostic (9.88e-2)" DCST1 FLJ32785 ENSG00000163357 "DC-STAMP domain containing 1" Q5T197 1 155033824-155050930 "Enzymes, Predicted membrane proteins" "Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "retina: 2.4;skin 1: 2.9;testis: 6.3" "Group enriched" "Detected in many" 5 "Cone photoreceptor cells: 49.7;Early spermatids: 32.0;Late primary spermatocytes: 50.8;Late spermatids: 28.6;Paneth cells: 15.5;Rod photoreceptor cells: 46.3" "Low cell type specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA060314 Uncertain Approved "Acrosome,Equatorial segment,Principal piece" NA NA "Cluster 47: Testis - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 79: Photoreceptor cells - Phototransduction" 1 "Principal piece" "Acrosome, Equatorial segment" "HPA060314: " "unprognostic (1.33e-1)" DCST2 FLJ32934 ENSG00000163354 "DC-STAMP domain containing 2" Q5T1A1 1 155018520-155033781 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "retina: 7.9;skin 1: 4.3" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 22.8;Early spermatids: 59.9;Extravillous trophoblasts: 26.4;Late primary spermatocytes: 46.7;Late spermatids: 41.8;Paneth cells: 19.3;Rod photoreceptor cells: 33.6" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" NA NA "Cluster 47: Testis - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" "unprognostic (1.89e-1)" "unprognostic (5.64e-2)" "unprognostic (6.15e-3)" DCSTAMP "DC-STAMP, FIND, TM7SF4" ENSG00000164935 "Dendrocyte expressed seven transmembrane protein" Q9H295 8 104339087-104356689 "Predicted membrane proteins, Transporters" "Differentiation, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 1.8;lung: 3.5" "Cell type enhanced" "Detected in some" "Hematopoietic stem cells: 2.4;Kupffer cells: 1.0;Macrophages: 14.4;monocytes: 5.8;Platelets: 4.2" "Group enriched" "Detected in some" 6 "amygdala excitatory: 13.4;deep-layer intratelencephalic: 4.9;hippocampal CA4: 8.1;thalamic excitatory: 5.2" "Cancer enriched" "Detected in some" 58 "Thyroid Carcinoma (TCGA): 64.9" "Region enhanced" "Detected in many" "amygdala: 9.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 1.6;thyroid cancer: 3.1" "Skin - Hair cortex cells, Skin - Inner root sheath cells" "Low region specificity" "Detected in many" "Not detected" "Not detected" NA NA "Cluster 13: Lung - Secretion" "Cluster 38: Sub-cortical - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 1 "unprognostic (3.55e-3)" "unprognostic (2.72e-2)" "unprognostic (3.22e-1)" "unprognostic (1.15e-2)" "unprognostic (1.00e-1)" "unprognostic (1.42e-1)" DCT "TRP-2, TRP2, TYRP2" ENSG00000080166 "Dopachrome tautomerase" P40126 13 94436811-94479682 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Melanin biosynthesis" Isomerase "Albinism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 35 "skin 1: 101.6" "Cell type enriched" "Detected in many" 90 "Melanocytes: 9101.9" "Cell type enriched" "Detected in many" 9 "committed oligodendrocyte precursor: 152.3" "Cancer enriched" "Detected in some" 203 "Skin Cutaneous Melanoma (TCGA): 338.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 26 "skin cancer: 361.4" "Liver - Hepatocytes, Skin - Melanocytes" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA010742, HPA010743, HPA010800, CAB017634" Enhanced Supported "Vesicles,Plasma membrane" NA NA "Cluster 37: Skin - Keratinization" "Cluster 33: Neurons - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 61: Schwann cells & Melanocytes - Mixed function" 7 "Plasma membrane" Vesicles "CAB017634: , HPA010742: , HPA010743: , HPA010800: " "unprognostic (3.25e-2)" "unprognostic (4.05e-3)" "unprognostic (1.94e-2)" DCTD ENSG00000129187 "DCMP deaminase" P32321 4 182890060-182917936 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Nucleotide biosynthesis" "Allosteric enzyme, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal suprabasal cells: 114.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA035894 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 22: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 97: Non-specific - Cellular respiration" 13 "Nucleoplasm, Cytosol" "HPA035894: " "unprognostic (5.98e-2)" "unprognostic (1.32e-1)" "potential prognostic unfavorable (2.87e-4)" "unprognostic (1.03e-1)" "unprognostic (3.37e-1)" "unprognostic (1.02e-1)" "unprognostic (1.88e-3)" "potential prognostic unfavorable (1.00e-5)" "unprognostic (3.16e-2)" "unprognostic (1.11e-1)" "potential prognostic favorable (1.69e-5)" "unprognostic (9.85e-2)" "unprognostic (9.47e-3)" "potential prognostic unfavorable (5.44e-4)" "unprognostic (1.22e-1)" "unprognostic (9.91e-3)" "unprognostic (3.02e-2)" "unprognostic (9.39e-3)" "unprognostic (2.31e-1)" "unprognostic (6.01e-2)" "unprognostic (1.26e-1)" "unprognostic (2.45e-2)" "unprognostic (2.17e-1)" "unprognostic (1.35e-1)" "unprognostic (1.17e-1)" "unprognostic (9.28e-2)" "unprognostic (1.25e-1)" "unprognostic (4.07e-1)" "unprognostic (5.62e-2)" "unprognostic (9.69e-2)" "unprognostic (1.16e-1)" DCTN1 ENSG00000204843 "Dynactin subunit 1" Q14203 2 74361154-74392087 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Transport" "Amyotrophic lateral sclerosis, Cancer-related genes, Neurodegeneration, Neuropathy, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Other brain neurons: 45.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009108, HPA034635, HPA069977, HPA071875" Approved Supported "Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Basal body,Acrosome,Perinuclear theca" Yes No 170000 "Cluster 25: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 98: Neurons - Neurotransmission & signaling" 168 Microtubules "Cytokinetic bridge, Mitotic spindle, Primary cilium, Basal body, Acrosome, Perinuclear theca" "CAB009108: , HPA034635: , HPA069977: , HPA071875: " "unprognostic (2.93e-1)" "unprognostic (1.64e-1)" "unprognostic (4.44e-2)" "unprognostic (1.80e-2)" "unprognostic (8.75e-2)" "unprognostic (1.54e-1)" "unprognostic (2.89e-1)" "potential prognostic favorable (1.61e-4)" "unprognostic (1.51e-1)" "unprognostic (1.89e-1)" "validated prognostic favorable (4.45e-9)" "validated prognostic favorable (7.92e-4)" "unprognostic (3.22e-2)" "unprognostic (1.86e-2)" "unprognostic (3.09e-3)" "unprognostic (4.18e-1)" "unprognostic (1.43e-1)" "unprognostic (6.76e-2)" "unprognostic (3.15e-1)" "unprognostic (4.64e-3)" "unprognostic (3.61e-2)" "unprognostic (1.98e-1)" "unprognostic (5.06e-2)" "unprognostic (1.24e-1)" "unprognostic (5.28e-2)" "unprognostic (1.86e-1)" "unprognostic (2.04e-1)" "unprognostic (1.37e-1)" "unprognostic (2.41e-1)" "unprognostic (4.81e-2)" "unprognostic (1.21e-1)" DCTN2 "DCTN-50, RBP50" ENSG00000175203 "Dynactin subunit 2" Q13561 12 57529633-57547224 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 522.6;Esophageal suprabasal cells: 309.3;Late spermatids: 425.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039715, HPA040040" Enhanced Supported "Centrosome,Basal body,Cytosol,Connecting piece,Mid piece,Principal piece,End piece" NA NA 660000 "Cluster 29: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 103 "Centrosome, Basal body" "Cytosol, Connecting piece, Mid piece, Principal piece, End piece" "HPA039715: , HPA040040: " "unprognostic (5.17e-2)" "unprognostic (1.89e-3)" "potential prognostic unfavorable (3.38e-4)" "unprognostic (3.32e-1)" "unprognostic (3.81e-2)" "unprognostic (7.78e-2)" "unprognostic (9.00e-2)" "unprognostic (1.44e-2)" "unprognostic (1.55e-1)" "unprognostic (2.47e-1)" "potential prognostic favorable (6.05e-5)" "unprognostic (9.88e-2)" "unprognostic (2.42e-1)" "validated prognostic unfavorable (4.78e-7)" "validated prognostic unfavorable (1.04e-5)" "unprognostic (3.73e-2)" "unprognostic (6.44e-3)" "unprognostic (1.01e-1)" "unprognostic (6.46e-2)" "unprognostic (4.25e-1)" "unprognostic (2.60e-1)" "unprognostic (4.19e-2)" "unprognostic (1.68e-2)" "unprognostic (2.62e-1)" "unprognostic (3.42e-1)" "unprognostic (3.48e-1)" "unprognostic (2.23e-1)" "unprognostic (4.05e-2)" "unprognostic (5.47e-1)" "unprognostic (1.60e-1)" "unprognostic (1.27e-1)" DCTN3 DCTN-22 ENSG00000137100 "Dynactin subunit 3" O75935 9 34613545-34620523 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 385.3;Esophageal suprabasal cells: 357.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044905 Approved Supported "Nucleoli,Cytosol,Perinuclear theca,Calyx,Mid piece,Principal piece" NA NA 27000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 97: Non-specific - Cellular respiration" 24 Cytosol "Nucleoli, Perinuclear theca, Calyx, Mid piece, Principal piece" "HPA044905: " "unprognostic (2.90e-2)" "unprognostic (3.25e-1)" "unprognostic (1.36e-2)" "unprognostic (1.21e-1)" "unprognostic (1.80e-1)" "unprognostic (2.61e-2)" "unprognostic (3.97e-1)" "potential prognostic favorable (1.24e-4)" "unprognostic (1.12e-1)" "unprognostic (7.56e-2)" "potential prognostic favorable (2.27e-10)" "unprognostic (1.45e-2)" "unprognostic (2.41e-3)" "unprognostic (2.85e-3)" "unprognostic (6.49e-3)" "unprognostic (6.34e-3)" "unprognostic (6.62e-3)" "unprognostic (2.15e-1)" "unprognostic (1.02e-1)" "potential prognostic favorable (1.68e-4)" "unprognostic (1.33e-1)" "unprognostic (1.55e-3)" "unprognostic (2.94e-1)" "unprognostic (3.37e-2)" "unprognostic (6.22e-2)" "unprognostic (1.29e-1)" "unprognostic (2.46e-2)" "unprognostic (7.66e-2)" "unprognostic (1.59e-1)" "unprognostic (8.70e-2)" "unprognostic (2.15e-2)" DCTN4 "Dyn4, p62" ENSG00000132912 "Dynactin subunit 4" Q9UJW0 5 150708440-150759095 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 314.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017532, HPA038026" Uncertain Approved Nucleoplasm,Centrosome,Calyx NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 103: Non-specific - Basic cellular processes" 48 "Nucleoplasm, Centrosome" Calyx "CAB017532: , HPA038026: " "unprognostic (2.92e-2)" "unprognostic (8.22e-2)" "unprognostic (2.48e-1)" "unprognostic (9.45e-3)" "unprognostic (1.14e-2)" "unprognostic (1.25e-1)" "unprognostic (2.15e-1)" "unprognostic (3.33e-2)" "unprognostic (6.15e-3)" "potential prognostic unfavorable (3.34e-4)" "potential prognostic favorable (2.50e-6)" "unprognostic (1.24e-2)" "unprognostic (2.41e-1)" "unprognostic (4.85e-3)" "unprognostic (2.15e-1)" "unprognostic (9.45e-2)" "unprognostic (2.35e-1)" "unprognostic (2.94e-1)" "unprognostic (4.52e-1)" "unprognostic (9.22e-2)" "unprognostic (7.27e-2)" "unprognostic (2.06e-1)" "unprognostic (1.87e-2)" "unprognostic (2.31e-1)" "unprognostic (4.42e-2)" "unprognostic (6.24e-2)" "unprognostic (3.01e-1)" "unprognostic (5.84e-2)" "unprognostic (4.57e-1)" "unprognostic (1.65e-2)" "unprognostic (3.14e-1)" DCTN5 "MGC3248, p25" ENSG00000166847 "Dynactin subunit 5" Q9BTE1 16 23641466-23677472 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 131.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042003, HPA063710" Approved Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 14: Neurons - Synaptic function" "Cluster 54: Non-specific - Transcription" "Cluster 35: Neurons - Synaptic function & neurogenesis" 37 "Nucleoplasm, Nuclear membrane" "HPA042003: , HPA063710: " "unprognostic (4.06e-2)" "unprognostic (1.73e-2)" "unprognostic (2.11e-1)" "unprognostic (1.48e-1)" "unprognostic (2.65e-1)" "unprognostic (2.12e-1)" "unprognostic (4.10e-1)" "potential prognostic favorable (2.60e-4)" "unprognostic (3.03e-2)" "unprognostic (4.01e-2)" "potential prognostic favorable (7.07e-6)" "unprognostic (9.62e-2)" "unprognostic (3.98e-2)" "unprognostic (4.76e-3)" "unprognostic (6.91e-2)" "unprognostic (4.11e-2)" "unprognostic (1.18e-2)" "unprognostic (1.45e-1)" "unprognostic (2.50e-1)" "unprognostic (1.82e-1)" "unprognostic (2.47e-3)" "unprognostic (8.86e-3)" "unprognostic (8.70e-3)" "unprognostic (2.70e-1)" "unprognostic (5.88e-2)" "unprognostic (1.61e-1)" "unprognostic (1.07e-1)" "unprognostic (2.34e-2)" "unprognostic (5.02e-2)" "unprognostic (7.64e-2)" "unprognostic (1.08e-1)" DCTN6 WS-3 ENSG00000104671 "Dynactin subunit 6" O00399 8 30156319-30183639 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 163.2;Syncytiotrophoblasts: 275.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024049, HPA024558" Approved Approved Cytosol NA Yes "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 27 Cytosol "HPA024049: , HPA024558: " "unprognostic (9.48e-2)" "unprognostic (1.57e-1)" "unprognostic (4.25e-1)" "unprognostic (1.11e-2)" "unprognostic (2.95e-2)" "unprognostic (1.46e-1)" "unprognostic (2.14e-1)" "unprognostic (8.45e-2)" "unprognostic (1.17e-1)" "unprognostic (5.45e-2)" "validated prognostic favorable (4.27e-9)" "validated prognostic favorable (3.27e-4)" "unprognostic (2.08e-1)" "potential prognostic unfavorable (7.45e-4)" "unprognostic (8.16e-2)" "unprognostic (6.02e-3)" "unprognostic (1.07e-1)" "unprognostic (2.18e-1)" "unprognostic (1.09e-1)" "unprognostic (8.28e-2)" "unprognostic (2.69e-3)" "unprognostic (2.17e-2)" "unprognostic (2.20e-2)" "unprognostic (1.63e-1)" "unprognostic (3.18e-2)" "unprognostic (8.50e-2)" "unprognostic (3.24e-1)" "unprognostic (4.07e-1)" "unprognostic (1.15e-1)" "unprognostic (3.43e-1)" "unprognostic (8.98e-2)" DCTPP1 "CDA03, MGC5627, RS21C6, XTP3TPA" ENSG00000179958 "DCTP pyrophosphatase 1" Q9H773 16 30423615-30430030 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 136.7;Enteric stem cells: 155.7;Enteric transient amplifying cells: 161.1;Esophageal basal cells: 169.7;Migrating cytotrophoblasts: 155.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002832 Uncertain Supported Nucleoplasm,Cytosol NA Yes 230000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 27: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 9 "Nucleoplasm, Cytosol" "HPA002832: " "unprognostic (1.67e-1)" "potential prognostic unfavorable (7.95e-6)" "unprognostic (4.69e-1)" "unprognostic (2.50e-1)" "unprognostic (4.62e-2)" "unprognostic (5.45e-3)" "unprognostic (2.38e-1)" "unprognostic (1.68e-1)" "unprognostic (1.14e-1)" "unprognostic (2.09e-3)" "potential prognostic favorable (2.21e-7)" "unprognostic (7.98e-2)" "potential prognostic favorable (8.94e-4)" "validated prognostic unfavorable (2.88e-5)" "validated prognostic unfavorable (2.27e-5)" "unprognostic (1.68e-1)" "unprognostic (1.04e-2)" "unprognostic (7.85e-2)" "unprognostic (2.47e-1)" "unprognostic (1.01e-1)" "unprognostic (2.92e-1)" "potential prognostic unfavorable (8.01e-4)" "unprognostic (2.20e-1)" "unprognostic (7.01e-2)" "unprognostic (3.03e-3)" "unprognostic (3.50e-1)" "unprognostic (1.33e-1)" "unprognostic (2.86e-2)" "unprognostic (7.36e-2)" "unprognostic (2.01e-2)" "unprognostic (2.95e-2)" DCUN1D1 "DCUN1L1, RP42, SCCRO, SCRO, Tes3" ENSG00000043093 "Defective in cullin neddylation 1 domain containing 1" Q96GG9 3 182938074-182985953 "Predicted intracellular proteins" "Ubl conjugation pathway" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "testis: 231.3" "Cell type enriched" "Detected in many" 8 "Late spermatids: 24837.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" HPA035911 Uncertain Approved Nucleoplasm,Cytosol NA NA 280000 "Cluster 7: Non-specific - Innate immune response" "Cluster 57: Testis - Spermatogenesis" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 35 Nucleoplasm Cytosol "HPA035911: " "unprognostic (3.41e-1)" "unprognostic (3.03e-2)" "unprognostic (3.67e-1)" "unprognostic (4.14e-2)" "unprognostic (2.34e-1)" "unprognostic (5.96e-2)" "unprognostic (8.76e-2)" "unprognostic (1.85e-1)" "unprognostic (7.34e-2)" "unprognostic (1.61e-2)" "potential prognostic favorable (8.70e-4)" "unprognostic (3.23e-1)" "unprognostic (7.66e-2)" "unprognostic (1.04e-1)" "unprognostic (3.64e-1)" "potential prognostic unfavorable (7.57e-6)" "unprognostic (5.90e-3)" "unprognostic (6.06e-2)" "unprognostic (1.12e-2)" "unprognostic (8.13e-2)" "potential prognostic unfavorable (1.33e-5)" "potential prognostic unfavorable (5.29e-5)" "unprognostic (5.23e-3)" "unprognostic (2.83e-2)" "unprognostic (4.66e-2)" "unprognostic (7.22e-2)" "unprognostic (8.51e-2)" "unprognostic (2.74e-1)" "unprognostic (3.51e-1)" "unprognostic (2.55e-2)" "unprognostic (6.49e-2)" DCUN1D2 "C13orf17, FLJ10704, FLJ20092" ENSG00000150401 "Defective in cullin neddylation 1 domain containing 2" Q6PH85 13 113455819-113490951 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 92.3;skeletal muscle: 101.9;tongue: 64.4" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 155.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 11.2" "Lineage enriched" "Detected in all" 4 "granulocytes: 11.2" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039349 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 5: Non-specific - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 9 "Plasma membrane, Cytosol" "HPA039349: " "unprognostic (3.09e-2)" "unprognostic (2.55e-2)" "unprognostic (3.85e-1)" "unprognostic (4.38e-2)" "unprognostic (7.64e-2)" "unprognostic (2.04e-1)" "unprognostic (6.80e-3)" "unprognostic (1.77e-3)" "unprognostic (4.48e-2)" "potential prognostic unfavorable (3.53e-4)" "unprognostic (8.31e-3)" "unprognostic (4.69e-2)" "unprognostic (2.98e-2)" "unprognostic (1.19e-1)" "unprognostic (3.23e-1)" "unprognostic (1.62e-1)" "unprognostic (9.75e-2)" "unprognostic (6.11e-2)" "unprognostic (1.68e-1)" "unprognostic (4.35e-2)" "unprognostic (3.31e-2)" "unprognostic (4.23e-3)" "unprognostic (1.08e-2)" "unprognostic (9.31e-2)" "unprognostic (8.88e-2)" "unprognostic (4.44e-2)" "unprognostic (1.51e-1)" "unprognostic (7.80e-2)" "unprognostic (1.84e-1)" "unprognostic (3.16e-2)" "unprognostic (8.21e-2)" DCUN1D3 "DKFZp686O0290, FLJ41725, MGC48972, SCCRO3" ENSG00000188215 "Defective in cullin neddylation 1 domain containing 3" Q8IWE4 16 20854925-20900358 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Early spermatids: 1.2;Gastric chief cells: 1.1;Late spermatids: 1.2;Medullary thymic epithelial cells: 2.4;Neutrophils: 1.1;Ocular epithelial cells: 1.3;Paneth cells: 3.9;Platelets: 1.4;Urothelial cells: 1.4" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041983, HPA043511" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 41: Basophils - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 55: Non-specific - Transcription" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 103: Non-specific - Basic cellular processes" 15 "Nucleoplasm, Cytosol" "HPA041983: , HPA043511: " "unprognostic (2.28e-1)" "unprognostic (2.85e-1)" "unprognostic (1.38e-1)" "unprognostic (6.88e-3)" "unprognostic (2.08e-1)" "unprognostic (6.04e-2)" "unprognostic (1.90e-1)" "unprognostic (4.96e-2)" "unprognostic (8.01e-2)" "unprognostic (3.79e-1)" "unprognostic (6.15e-2)" "unprognostic (1.84e-1)" "unprognostic (2.09e-2)" "unprognostic (3.55e-2)" "unprognostic (1.18e-1)" "unprognostic (9.78e-2)" "unprognostic (1.06e-2)" "unprognostic (7.35e-2)" "unprognostic (3.02e-1)" "unprognostic (2.49e-2)" "unprognostic (8.55e-2)" "unprognostic (6.70e-2)" "unprognostic (4.31e-2)" "unprognostic (1.25e-1)" "unprognostic (1.11e-1)" "unprognostic (1.66e-1)" "unprognostic (5.04e-2)" "unprognostic (9.37e-2)" "unprognostic (1.57e-1)" "unprognostic (2.36e-1)" "unprognostic (2.87e-1)" DCUN1D4 KIAA0276 ENSG00000109184 "Defective in cullin neddylation 1 domain containing 4" Q92564 4 51843000-51916837 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036483, HPA036484" Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 76: Non-specific - Metabolism" "Cluster 1: Neurons - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 8 Vesicles Nucleoplasm "HPA036483: , HPA036484: " "unprognostic (6.97e-2)" "unprognostic (1.37e-2)" "unprognostic (1.48e-1)" "unprognostic (1.59e-1)" "unprognostic (4.93e-2)" "unprognostic (1.50e-1)" "unprognostic (1.94e-1)" "unprognostic (2.33e-2)" "unprognostic (3.58e-1)" "unprognostic (5.92e-3)" "unprognostic (1.41e-3)" "unprognostic (4.39e-3)" "unprognostic (1.25e-1)" "unprognostic (3.53e-3)" "unprognostic (3.48e-2)" "unprognostic (4.39e-2)" "unprognostic (8.17e-2)" "unprognostic (5.38e-2)" "unprognostic (1.07e-1)" "unprognostic (1.07e-1)" "unprognostic (1.17e-1)" "unprognostic (3.30e-2)" "unprognostic (3.79e-3)" "unprognostic (1.17e-1)" "unprognostic (7.01e-2)" "unprognostic (1.85e-1)" "unprognostic (4.74e-2)" "unprognostic (1.63e-1)" "unprognostic (7.19e-2)" "unprognostic (1.62e-3)" "unprognostic (2.39e-1)" DCUN1D5 "FLJ32431, MGC2714" ENSG00000137692 "Defective in cullin neddylation 1 domain containing 5" Q9BTE7 11 103050686-103092194 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 193.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Bile duct cancer: 66.5" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050863 Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - DNA binding" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 17: Non-specific - RNA processing" 19 Nucleoli Nucleoplasm "HPA050863: " "unprognostic (1.48e-1)" "unprognostic (3.11e-2)" "unprognostic (2.67e-1)" "unprognostic (4.49e-1)" "unprognostic (8.94e-2)" "unprognostic (1.02e-1)" "unprognostic (1.06e-1)" "unprognostic (4.87e-2)" "unprognostic (2.06e-2)" "unprognostic (1.70e-1)" "validated prognostic unfavorable (8.12e-7)" "validated prognostic unfavorable (3.94e-4)" "unprognostic (1.48e-1)" "potential prognostic unfavorable (3.30e-4)" "unprognostic (8.05e-3)" "unprognostic (1.43e-3)" "unprognostic (3.86e-2)" "potential prognostic favorable (4.55e-4)" "unprognostic (1.14e-1)" "unprognostic (2.19e-3)" "unprognostic (2.17e-1)" "unprognostic (1.97e-2)" "potential prognostic unfavorable (2.55e-4)" "unprognostic (3.25e-2)" "unprognostic (1.95e-1)" "unprognostic (6.79e-2)" "potential prognostic unfavorable (9.88e-4)" "unprognostic (9.24e-2)" "unprognostic (2.28e-1)" "unprognostic (1.59e-1)" "unprognostic (1.57e-1)" DCX "DBCN, DC, LISX, SCLH, XLIS" ENSG00000077279 Doublecortin O43602 X 111293779-111412429 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Disease variant, Epilepsy, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.8;retina: 2.0" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 32.2;Brain inhibitory neurons: 94.3;Corticotrophs: 21.6;Extravillous trophoblasts: 20.9;Gonadotrophs: 16.3;Oligodendrocyte progenitor cells: 53.5;Other brain neurons: 64.5;Rod photoreceptor cells: 36.7" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in some" 5 "Glioblastoma Multiforme (TCGA): 9.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 10 "Neuroblastoma: 31.0" "Adrenal gland - Adrenal medulla cells, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Beta cells, Pituitary gland - Thyrotropes, Skin - Fibroblasts_1" "Region enriched" "Detected in many" 9 "olfactory bulb: 74.0" "Region enriched" "Detected in all" 5 "olfactory bulb: 103.8" "HPA036121, HPA059243" Enhanced Supported Enhanced Cytosol NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 21 Cytosol "HPA036121: , HPA059243: " "unprognostic (1.32e-1)" "unprognostic (2.05e-1)" "potential prognostic favorable (2.91e-4)" "unprognostic (1.28e-1)" DCXR "DCR, HCR2, KIDCR, P34H, SDR20C1" ENSG00000169738 "Dicarbonyl and L-xylulose reductase" Q7Z4W1 17 82035136-82037709 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism, Xylose metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "liver: 1923.6" "Cell type enhanced" "Detected in many" "Breast lactating cells: 1053.9;Epididymal efferent duct absorptive cells: 673.8;Epididymal principal cells: 1490.2;Extravillous trophoblasts: 619.8;Hepatocytes: 4221.6" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Liver Hepatocellular Carcinoma (TCGA): 886.6;Prostate Adenocarcinoma (TCGA): 496.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Pituitary gland - Corticotropes, Prostate - Prostate glandular cells, Stomach - Chief cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023371, HPA023863" Enhanced Approved Microtubules NA NA 4700000 "Cluster 29: Non-specific - Unknown function" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 45: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 93: Hepatocytes - Bile production & excretion" 2 Microtubules "HPA023371: , HPA023863: " "unprognostic (3.11e-1)" "unprognostic (3.18e-2)" "unprognostic (2.62e-1)" "unprognostic (2.20e-1)" "unprognostic (4.65e-2)" "unprognostic (7.43e-2)" "unprognostic (1.71e-1)" "unprognostic (1.38e-1)" "unprognostic (1.74e-1)" "unprognostic (5.08e-3)" "unprognostic (5.58e-2)" "unprognostic (1.42e-1)" "unprognostic (1.83e-1)" "unprognostic (5.16e-3)" "potential prognostic favorable (2.62e-4)" "unprognostic (2.54e-1)" "unprognostic (1.88e-1)" "unprognostic (5.66e-2)" "unprognostic (4.94e-2)" "unprognostic (9.86e-2)" "unprognostic (1.51e-2)" "unprognostic (1.63e-3)" "unprognostic (9.89e-2)" "unprognostic (1.44e-2)" "unprognostic (7.21e-2)" "unprognostic (7.62e-3)" "unprognostic (7.21e-2)" "unprognostic (2.18e-1)" "unprognostic (2.38e-1)" "unprognostic (8.47e-2)" "unprognostic (1.09e-1)" DDA1 "C19orf58, MGC2594, PCIA1" ENSG00000130311 "DET1 and DDB1 associated 1" Q9BW61 19 17309518-17323298 "Essential proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 151.9;Early spermatids: 473.3;Esophageal apical cells: 245.7;Extravillous trophoblasts: 196.5;Late primary spermatocytes: 293.2;Late spermatids: 158.8;Migrating cytotrophoblasts: 202.1;Syncytiotrophoblasts: 306.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042134, HPA055272" Approved Approved Nucleoplasm,Nucleoli No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 71 "Nucleoplasm, Nucleoli" "HPA042134: , HPA055272: " "unprognostic (1.71e-2)" "unprognostic (3.32e-1)" "unprognostic (2.34e-1)" "unprognostic (1.05e-1)" "unprognostic (9.34e-3)" "unprognostic (4.56e-2)" "unprognostic (9.02e-2)" "unprognostic (1.27e-1)" "unprognostic (5.01e-3)" "unprognostic (3.43e-1)" "unprognostic (1.55e-2)" "unprognostic (1.10e-1)" "unprognostic (1.01e-1)" "unprognostic (4.90e-3)" "unprognostic (2.04e-3)" "unprognostic (9.61e-3)" "unprognostic (3.07e-1)" "unprognostic (1.75e-1)" "unprognostic (1.05e-2)" "unprognostic (1.39e-1)" "unprognostic (2.00e-1)" "unprognostic (7.97e-2)" "unprognostic (1.27e-1)" "unprognostic (2.58e-2)" "unprognostic (1.11e-1)" "unprognostic (2.18e-1)" "unprognostic (3.94e-1)" "unprognostic (4.37e-2)" "unprognostic (1.70e-1)" "unprognostic (4.27e-2)" "unprognostic (1.40e-1)" DDAH1 DDAH ENSG00000153904 "Dimethylarginine dimethylaminohydrolase 1" O94760 1 85318481-85578363 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 116.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 337.5;Astrocytes: 423.4;Ependymal cells: 330.8;Hepatic stellate cells: 426.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Fibroblasts_1, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006308, HPA071064" Enhanced Approved "Nucleoli,Plasma membrane,Cytosol" NA NA 750000 "Cluster 36: Brain & Liver - Signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 51: Secretory epithelial cells - Mixed function" 2 "Plasma membrane, Cytosol" Nucleoli "HPA006308: , HPA071064: " "unprognostic (1.79e-2)" "unprognostic (1.17e-1)" "unprognostic (2.50e-1)" "unprognostic (1.66e-1)" "potential prognostic favorable (2.19e-4)" "unprognostic (1.50e-1)" "unprognostic (2.74e-2)" "unprognostic (4.67e-1)" "unprognostic (1.89e-2)" "unprognostic (4.26e-2)" "validated prognostic favorable (1.08e-13)" "validated prognostic favorable (1.05e-4)" "unprognostic (2.22e-2)" "unprognostic (1.32e-1)" "unprognostic (6.96e-2)" "unprognostic (1.37e-1)" "unprognostic (5.37e-2)" "unprognostic (7.75e-2)" "unprognostic (5.62e-2)" "unprognostic (1.09e-1)" "unprognostic (8.07e-2)" "unprognostic (9.90e-2)" "unprognostic (2.47e-3)" "unprognostic (9.47e-2)" "unprognostic (3.50e-1)" "unprognostic (7.80e-2)" "unprognostic (1.10e-1)" "unprognostic (5.71e-2)" "unprognostic (1.95e-1)" "unprognostic (2.14e-1)" "unprognostic (2.80e-1)" DDAH2 G6A ENSG00000213722 "Dimethylarginine dimethylaminohydrolase 2" O95865 6 31727038-31730617 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast secretory cells: 100.6;Colonocytes: 101.2;Decidual stromal cells: 130.3;Hofbauer cells: 95.3;Kupffer cells: 89.2" "Group enriched" "Detected in many" 4 "astrocyte: 25.2;Bergmann glia: 28.8;central nervous system macrophage: 29.2;endothelial cell: 46.7;ependymal cell: 39.8;fibroblast: 37.5;leukocyte: 17.9;oligodendrocyte precursor cell: 15.8;pericyte: 44.6;vascular associated smooth muscle cell: 51.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012389, HPA012509" Uncertain Supported Mitochondria NA NA 1800000 "Cluster 22: Eosinophils - Transcription" "Cluster 74: Non-specific - Signal transduction" "Cluster 39: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 15 Mitochondria "HPA012389: , HPA012509: " "unprognostic (5.04e-2)" "unprognostic (5.37e-3)" "unprognostic (6.76e-2)" "unprognostic (8.61e-2)" "unprognostic (1.48e-2)" "unprognostic (1.68e-1)" "unprognostic (9.76e-2)" "unprognostic (5.06e-2)" "unprognostic (1.76e-2)" "unprognostic (2.48e-1)" "unprognostic (1.17e-3)" "unprognostic (6.84e-2)" "unprognostic (1.68e-2)" "potential prognostic unfavorable (5.27e-8)" "unprognostic (4.83e-3)" "unprognostic (1.00e-1)" "unprognostic (1.41e-1)" "unprognostic (9.64e-2)" "unprognostic (1.70e-1)" "unprognostic (2.55e-1)" "unprognostic (2.24e-1)" "unprognostic (3.12e-1)" "unprognostic (7.48e-2)" "unprognostic (3.49e-2)" "unprognostic (4.84e-2)" "unprognostic (7.16e-2)" "unprognostic (5.50e-3)" "unprognostic (1.29e-1)" "unprognostic (4.54e-3)" "unprognostic (3.42e-1)" "unprognostic (6.32e-2)" DDB1 ENSG00000167986 "Damage specific DNA binding protein 1" Q16531 11 61299451-61342596 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, DNA damage, DNA repair, Host-virus interaction, Ubl conjugation pathway" DNA-binding "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adrenal cortex cells: 305.7;Cytotrophoblasts: 391.0;Rod photoreceptor cells: 385.8;Syncytiotrophoblasts: 543.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032821, HPA045174, HPA068456" Approved Enhanced "Nucleoplasm,Mid piece,Principal piece,End piece" NA NA 860000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 27: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 307 Nucleoplasm "Mid piece, Principal piece, End piece" "CAB032821: , HPA045174: , HPA068456: " "unprognostic (3.76e-2)" "unprognostic (1.06e-1)" "unprognostic (7.12e-2)" "unprognostic (1.09e-2)" "unprognostic (9.69e-2)" "unprognostic (2.23e-1)" "unprognostic (2.32e-2)" "unprognostic (2.49e-3)" "unprognostic (2.02e-2)" "unprognostic (7.87e-3)" "potential prognostic favorable (2.28e-8)" "unprognostic (1.14e-2)" "unprognostic (3.78e-2)" "unprognostic (9.34e-3)" "unprognostic (1.81e-3)" "unprognostic (1.44e-2)" "unprognostic (1.72e-3)" "unprognostic (1.35e-1)" "unprognostic (1.56e-1)" "unprognostic (1.17e-1)" "unprognostic (3.15e-1)" "unprognostic (1.85e-2)" "unprognostic (3.25e-1)" "unprognostic (4.33e-1)" "unprognostic (1.55e-2)" "unprognostic (1.31e-1)" "unprognostic (5.36e-2)" "unprognostic (2.60e-1)" "unprognostic (2.83e-1)" "unprognostic (5.39e-2)" "unprognostic (4.55e-2)" DDB2 "DDBB, FLJ34321, UV-DDB2, XPE" ENSG00000134574 "Damage specific DNA binding protein 2" Q92466 11 47214465-47239217 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" DNA-binding "Cancer-related genes, Disease variant, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 120.5" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 79.6;leukocyte: 58.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025912, HPA058406" Enhanced Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 58: Skin - Keratinization" "Cluster 30: White matter - Myelination" "Cluster 40: Non-specific - Unknown function" "Cluster 26: Keratinocytes - Keratinization" 82 "Nucleoplasm, Cell Junctions" "CAB025912: , HPA058406: " "unprognostic (9.99e-2)" "unprognostic (6.00e-2)" "unprognostic (2.51e-1)" "unprognostic (1.60e-1)" "unprognostic (7.66e-2)" "unprognostic (2.21e-1)" "unprognostic (2.54e-2)" "potential prognostic unfavorable (3.82e-5)" "unprognostic (1.26e-1)" "unprognostic (2.11e-1)" "validated prognostic favorable (2.50e-10)" "validated prognostic favorable (1.22e-4)" "unprognostic (3.41e-3)" "unprognostic (5.18e-2)" "unprognostic (7.95e-2)" "unprognostic (9.16e-2)" "unprognostic (8.83e-2)" "unprognostic (1.45e-2)" "unprognostic (9.09e-2)" "unprognostic (2.63e-1)" "unprognostic (1.73e-2)" "unprognostic (4.63e-2)" "unprognostic (3.24e-2)" "unprognostic (8.30e-2)" "unprognostic (3.78e-1)" "unprognostic (1.91e-1)" "unprognostic (7.88e-2)" "unprognostic (1.38e-2)" "unprognostic (4.43e-2)" "unprognostic (1.23e-2)" "unprognostic (1.07e-1)" DDC AADC ENSG00000132437 "Dopa decarboxylase" P20711 7 50458436-50565405 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Catecholamine biosynthesis" "Decarboxylase, Lyase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 156.1;kidney: 294.0;retina: 162.8" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 63.8;Enterocytes: 32.7;Neuroendocrine cells: 32.9;Proximal tubule cells: 16.3;Retinal bipolar cells: 10.7;Retinal ganglion cells: 11.6;Retinal horizontal cells: 14.0;Rod photoreceptor cells: 108.9" "Cell type enhanced" "Detected in single" "splatter: 1.3" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 9 "midbrain: 179.5;pons: 59.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 108.9" "Adrenal gland - Adrenal medulla cells, Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Sebaceous gland cells, Testis - Early spermatids, Thyroid gland - Parafollicular cells" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "midbrain: 97.7;pons: 40.1" HPA017742 Enhanced Approved "Actin filaments,Primary cilium" NA NA 130000 "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 79: Photoreceptor cells - Phototransduction" 1 "Actin filaments" "Primary cilium" "HPA017742: " "unprognostic (2.47e-1)" "unprognostic (1.89e-1)" "unprognostic (3.38e-2)" "unprognostic (1.47e-2)" "potential prognostic favorable (2.83e-8)" "unprognostic (1.73e-3)" "unprognostic (5.61e-2)" "unprognostic (2.73e-1)" "potential prognostic unfavorable (1.71e-5)" "unprognostic (9.25e-2)" "unprognostic (1.47e-1)" "unprognostic (4.93e-3)" "unprognostic (2.96e-2)" "unprognostic (4.48e-2)" "unprognostic (4.61e-3)" "unprognostic (1.85e-2)" "unprognostic (1.67e-2)" "unprognostic (1.02e-3)" "unprognostic (3.45e-1)" "unprognostic (6.25e-2)" "unprognostic (3.79e-1)" "potential prognostic unfavorable (2.27e-4)" DDHD1 "iPLA1alpha, KIAA1705, PA-PLA1, PAPLA1, SPG28" ENSG00000100523 "DDHD domain containing 1" Q8NEL9 14 53036745-53153323 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Phospholipid metabolism" Hydrolase "Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 28.8" "Cell type enhanced" "Detected in many" "Early spermatids: 358.4;Gonadotrophs: 238.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Spleen - B-cells (Spleen), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049870 Enhanced NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 65: Brain - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 7: Non-specific - Transcription" 5 "HPA049870: " "unprognostic (1.01e-1)" "unprognostic (1.11e-1)" "unprognostic (1.49e-1)" "unprognostic (2.03e-1)" "unprognostic (1.43e-1)" "unprognostic (1.22e-1)" "unprognostic (7.21e-3)" "unprognostic (8.54e-3)" "unprognostic (1.92e-1)" "unprognostic (1.28e-3)" "unprognostic (4.07e-2)" "unprognostic (1.83e-3)" "unprognostic (1.46e-1)" "unprognostic (2.68e-2)" "unprognostic (7.12e-2)" "unprognostic (1.55e-1)" "unprognostic (1.33e-1)" "unprognostic (9.22e-2)" "unprognostic (1.76e-2)" "unprognostic (5.67e-2)" "unprognostic (1.41e-1)" "unprognostic (3.15e-2)" "unprognostic (5.25e-3)" "unprognostic (1.73e-1)" "unprognostic (1.59e-1)" "potential prognostic favorable (7.03e-4)" "unprognostic (6.94e-2)" "unprognostic (3.10e-1)" "unprognostic (9.68e-2)" "unprognostic (9.46e-2)" "unprognostic (1.00e-1)" DDHD2 "iPLA1gamma, KIAA0725, p125B, SAMWD1, SPG54" ENSG00000085788 "DDHD domain containing 2" O94830 8 38225218-38275558 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 165.6;Epicardial cells: 218.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015202, HPA023143, HPA023147" Supported Supported "Centriolar satellite,Cytosol" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 37: Neurons - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 5 Cytosol "Centriolar satellite" "CAB015202: , HPA023143: , HPA023147: " "unprognostic (2.26e-2)" "unprognostic (1.34e-2)" "unprognostic (2.32e-1)" "unprognostic (1.95e-2)" "unprognostic (2.73e-1)" "unprognostic (3.05e-2)" "unprognostic (1.98e-1)" "unprognostic (6.39e-3)" "unprognostic (5.34e-3)" "potential prognostic unfavorable (1.63e-4)" "potential prognostic favorable (6.15e-6)" "unprognostic (9.22e-3)" "unprognostic (2.57e-2)" "unprognostic (4.83e-2)" "unprognostic (9.50e-2)" "unprognostic (1.33e-1)" "unprognostic (1.92e-1)" "unprognostic (5.90e-2)" "unprognostic (8.45e-3)" "unprognostic (5.04e-3)" "unprognostic (1.16e-2)" "unprognostic (3.90e-1)" "unprognostic (7.73e-2)" "unprognostic (3.69e-2)" "unprognostic (1.03e-1)" "unprognostic (2.89e-2)" "unprognostic (1.08e-1)" "unprognostic (1.71e-1)" "unprognostic (1.59e-1)" "unprognostic (2.59e-2)" "unprognostic (3.57e-1)" DDI1 FLJ36017 ENSG00000170967 "DNA damage inducible 1 homolog 1" Q8WTU0 11 104036640-104039196 "Predicted intracellular proteins" "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 241 "testis: 24.1" "Cell type enhanced" "Detected in some" "Early spermatids: 393.2;Late primary spermatocytes: 259.4;Late spermatids: 1504.0" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA079511 Enhanced NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 23: Choroid plexus - Mixed function" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 23 "HPA079511: " DDI2 MGC14844 ENSG00000197312 "DNA damage inducible 1 homolog 2" Q5TDH0 1 15617458-15669044 "Plasma proteins, Predicted intracellular proteins" "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 178.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "HPA043119, HPA043225" Approved Enhanced Nucleoplasm,Cytosol NA NA 720000 "Cluster 30: Non-specific - DNA binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 7: Non-specific - Transcription" 9 "Nucleoplasm, Cytosol" "HPA043119: , HPA043225: " "unprognostic (1.09e-1)" "unprognostic (8.36e-2)" "unprognostic (6.07e-2)" "unprognostic (9.19e-3)" "unprognostic (1.53e-2)" "unprognostic (1.40e-1)" "unprognostic (1.19e-1)" "unprognostic (9.32e-2)" "unprognostic (1.80e-3)" "potential prognostic unfavorable (1.97e-4)" "validated prognostic favorable (1.91e-6)" "validated prognostic favorable (8.68e-6)" "unprognostic (2.99e-3)" "unprognostic (3.45e-2)" "unprognostic (7.26e-2)" "unprognostic (1.71e-1)" "unprognostic (1.98e-2)" "unprognostic (5.89e-2)" "unprognostic (7.86e-2)" "unprognostic (3.02e-2)" "unprognostic (1.42e-1)" "unprognostic (1.44e-3)" "unprognostic (2.29e-2)" "unprognostic (2.26e-1)" "unprognostic (1.46e-1)" "unprognostic (4.07e-3)" "unprognostic (6.49e-3)" "unprognostic (1.53e-1)" "unprognostic (4.12e-1)" "unprognostic (2.66e-2)" "unprognostic (1.94e-1)" DDIAS "C11orf82, FLJ25416, FLJ38838, noxin" ENSG00000165490 "DNA damage induced apoptosis suppressor" Q8IXT1 11 82899975-82958277 "Predicted intracellular proteins" "Apoptosis, Cell cycle, Growth arrest" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 7.4;testis: 10.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 55.5;Differentiating spermatogonia: 30.9;Early primary spermatocytes: 21.4;Epicardial cells: 29.6;Erythrocyte progenitors: 20.8;Kupffer cells: 22.5;Megakaryocyte progenitors: 15.5;Monocyte progenitors: 26.2;Neutrophil progenitors: 30.5;Neutrophils: 19.8;Plasma cells: 21.7;Undifferentiated spermatogonia: 15.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA038540, HPA038541" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 11: White matter - Signal transduction" "Cluster 24: Non-specific - Unknown function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 1 "Plasma membrane, Cytosol" "HPA038540: , HPA038541: " "unprognostic (2.93e-1)" "unprognostic (2.48e-1)" "unprognostic (2.08e-2)" "unprognostic (2.61e-1)" "unprognostic (1.07e-1)" "unprognostic (9.58e-2)" "unprognostic (2.39e-1)" "unprognostic (1.01e-1)" "unprognostic (6.00e-3)" "potential prognostic unfavorable (3.69e-5)" "validated prognostic unfavorable (7.63e-4)" "validated prognostic unfavorable (8.52e-4)" "unprognostic (1.46e-2)" "unprognostic (7.54e-3)" "unprognostic (6.81e-2)" "unprognostic (6.20e-2)" "potential prognostic unfavorable (2.54e-4)" "unprognostic (2.72e-3)" "unprognostic (8.78e-3)" "unprognostic (1.87e-3)" "unprognostic (2.60e-3)" "unprognostic (2.53e-2)" "unprognostic (1.56e-1)" "unprognostic (2.96e-1)" DDIT3 "CHOP, CHOP10, GADD153" ENSG00000175197 "DNA damage inducible transcript 3" P35638 12 57516588-57521737 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Cell cycle, Growth arrest, Stress response, Transcription, Transcription regulation, Unfolded protein response, Wnt signaling pathway" "Activator, DNA-binding, Repressor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Epididymal principal cells: 3123.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 291.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 170.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058416, HPA068416" Uncertain Supported Nucleoplasm No No "Cluster 21: Neutrophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" 73 Nucleoplasm "HPA058416: , HPA068416: " "unprognostic (1.59e-1)" "unprognostic (6.69e-3)" "unprognostic (1.40e-1)" "unprognostic (2.68e-1)" "unprognostic (1.17e-2)" "unprognostic (2.38e-2)" "unprognostic (1.72e-2)" "unprognostic (9.47e-2)" "unprognostic (4.48e-2)" "unprognostic (3.79e-2)" "potential prognostic unfavorable (9.20e-6)" "unprognostic (6.97e-2)" "unprognostic (4.57e-2)" "potential prognostic unfavorable (7.09e-4)" "unprognostic (1.28e-1)" "unprognostic (3.62e-1)" "unprognostic (7.55e-2)" "unprognostic (1.14e-1)" "unprognostic (2.17e-1)" "unprognostic (2.36e-2)" "unprognostic (1.27e-1)" "unprognostic (6.76e-2)" "unprognostic (7.96e-3)" "unprognostic (9.13e-3)" "unprognostic (2.58e-1)" "unprognostic (1.64e-1)" "potential prognostic unfavorable (3.90e-5)" "unprognostic (2.69e-1)" "unprognostic (3.31e-1)" "unprognostic (1.46e-1)" "unprognostic (4.63e-2)" DDIT4 "Dig2, FLJ20500, REDD-1, REDD1, RTP801" ENSG00000168209 "DNA damage inducible transcript 4" Q9NX09 10 72273919-72276036 "Predicted intracellular proteins" "Antiviral defense, Apoptosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 903.1;Breast lactating cells: 800.6;Esophageal apical cells: 4026.6;Esophageal suprabasal cells: 1521.5;Pancreatic acinar cells: 804.7;Prostatic hillock cells: 1045.8" "Cell type enhanced" "Detected in all" "astrocyte: 315.6;Bergmann glia: 121.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034507, HPA034508" Approved Supported Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 54: Non-specific - Ribosome" "Cluster 25: Non-specific - Transcription" "Cluster 13: Non-specific - Mixed function" "Cluster 85: Squamous epithelial cells - Keratinization" 12 Cytosol "HPA034507: , HPA034508: " "unprognostic (1.78e-1)" "unprognostic (4.14e-3)" "unprognostic (2.43e-1)" "unprognostic (1.44e-3)" "unprognostic (1.02e-1)" "unprognostic (2.91e-2)" "unprognostic (8.25e-2)" "unprognostic (2.55e-1)" "potential prognostic unfavorable (1.08e-5)" "unprognostic (3.98e-2)" "unprognostic (6.20e-2)" "unprognostic (3.38e-2)" "unprognostic (8.49e-3)" "unprognostic (7.61e-2)" "potential prognostic unfavorable (1.52e-4)" "validated prognostic unfavorable (1.82e-4)" "validated prognostic unfavorable (5.37e-4)" "unprognostic (1.58e-1)" "unprognostic (2.56e-3)" "unprognostic (4.76e-3)" "unprognostic (1.80e-1)" "validated prognostic unfavorable (1.65e-4)" "validated prognostic unfavorable (1.95e-4)" "unprognostic (1.04e-2)" "unprognostic (3.73e-1)" "unprognostic (1.74e-2)" "unprognostic (6.07e-2)" "unprognostic (3.39e-2)" "unprognostic (1.21e-1)" "unprognostic (1.34e-1)" "unprognostic (1.95e-1)" DDIT4L "REDD2, Rtp801L" ENSG00000145358 "DNA damage inducible transcript 4 like" Q96D03 4 100185870-100190782 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "skeletal muscle: 303.4;tongue: 99.8" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 76.7;Endometrial secretory cells: 19.1;Extravillous trophoblasts: 25.9;Hofbauer cells: 27.4;Myonuclei: 53.6;Salivary basal cells: 20.4;Salivary duct cells: 28.6;Salivary ionocytes: 18.1;Thymic myoid cells: 96.5" "Cell type enhanced" "Detected in some" "Bergmann glia: 15.1;medium spiny neuron: 13.2" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 32.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 8.1" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050903 Approved "Nucleoplasm,Plasma membrane,Actin filaments" NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 19: Astrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 171 "Plasma membrane" "Nucleoplasm, Actin filaments" "HPA050903: " "unprognostic (1.38e-1)" "unprognostic (1.33e-1)" "unprognostic (5.00e-2)" "unprognostic (8.12e-2)" "unprognostic (1.84e-3)" "potential prognostic unfavorable (8.04e-4)" "unprognostic (4.74e-2)" "potential prognostic unfavorable (3.09e-4)" "validated prognostic favorable (4.28e-5)" "validated prognostic favorable (3.32e-4)" "unprognostic (1.64e-3)" "unprognostic (3.20e-1)" "unprognostic (1.51e-1)" "unprognostic (1.04e-2)" "unprognostic (2.68e-2)" "unprognostic (1.55e-2)" "unprognostic (1.53e-2)" "unprognostic (3.13e-1)" "unprognostic (2.82e-1)" "unprognostic (2.47e-1)" "unprognostic (2.73e-1)" "unprognostic (1.32e-2)" "unprognostic (6.11e-2)" DDN KIAA0749 ENSG00000181418 Dendrin O94850 12 48995149-48999375 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "brain: 234.0;skeletal muscle: 277.8" "Cell type enriched" "Detected in some" 11 "Podocytes: 117.2" "Cell type enhanced" "Detected in many" "eccentric medium spiny neuron: 27.2" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 3.4;Head and Neck Squamous Cell Carcinoma (TCGA): 3.7" "Group enriched" "Detected in all" 7 "amygdala: 357.7;basal ganglia: 287.4;cerebral cortex: 408.4;hippocampal formation: 307.9;white matter: 160.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 11.7" "Kidney - Podocytes, Pituitary gland - Gonadotropes, Spleen - Mitotic cells (Spleen), Stomach - Parietal cells" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 14 "amygdala: 215.8;basal ganglia: 277.5;cerebral cortex: 232.8;hippocampal formation: 223.4;olfactory bulb: 82.8" HPA060952 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 51: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 57: Podocytes - Glomerular filtration" 3 Nucleoplasm Cytosol "HPA060952: " "unprognostic (2.42e-1)" "unprognostic (1.18e-2)" "unprognostic (2.19e-1)" "unprognostic (8.60e-2)" "unprognostic (4.17e-3)" "unprognostic (5.99e-3)" "unprognostic (5.14e-2)" DDO "DASOX, DASPO" ENSG00000203797 "D-aspartate oxidase" Q99489 6 110391771-110415575 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 17.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 52.2;Fallopian tube ciliated cells: 10.1;Myonuclei: 16.1;Oligodendrocytes: 10.2;Paneth cells: 11.6" "Cell type enhanced" "Detected in many" "hippocampal dentate gyrus: 14.6;medium spiny neuron: 11.0;oligodendrocyte: 16.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 3.3;myeloid DC: 4.7" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Rhabdoid: 5.8" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Pituitary gland - Undifferentiated cells (Pituitary gland)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037525, HPA037526" Enhanced Enhanced Cytosol NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 1 Cytosol "HPA037525: , HPA037526: " "unprognostic (7.53e-2)" "unprognostic (2.54e-1)" "unprognostic (2.53e-1)" "unprognostic (1.11e-2)" "unprognostic (2.71e-1)" "unprognostic (1.25e-1)" "unprognostic (1.44e-1)" "unprognostic (1.29e-1)" "unprognostic (1.77e-1)" "potential prognostic favorable (1.56e-8)" "unprognostic (1.28e-2)" "unprognostic (1.07e-2)" "unprognostic (3.06e-2)" "unprognostic (1.20e-1)" "unprognostic (8.12e-3)" "unprognostic (6.74e-2)" "unprognostic (6.59e-3)" "unprognostic (1.60e-1)" "unprognostic (3.09e-1)" "unprognostic (3.82e-2)" "unprognostic (2.58e-1)" "unprognostic (8.66e-2)" "unprognostic (4.05e-1)" "unprognostic (4.08e-3)" "unprognostic (5.65e-2)" "unprognostic (1.13e-1)" "unprognostic (1.76e-3)" "unprognostic (1.61e-2)" "unprognostic (2.00e-1)" DDOST "KIAA0115, OST, OST48, WBP1" ENSG00000244038 "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit" P39656 1 20651767-20661544 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 403.7;Extravillous trophoblasts: 370.9;Migrating cytotrophoblasts: 367.7;Plasma cells: 320.2;Syncytiotrophoblasts: 400.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Macrophages, Prostate - Macrophages, Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009746, HPA046841, HPA052867" Supported Supported "Endoplasmic reticulum" NA NA 140000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 70: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 8: Non-specific - Secretory pathway" 194 "Endoplasmic reticulum" "CAB009746: , HPA046841: , HPA052867: " "unprognostic (3.69e-2)" "unprognostic (6.70e-3)" "unprognostic (7.42e-2)" "potential prognostic unfavorable (1.81e-5)" "potential prognostic favorable (1.07e-4)" "unprognostic (9.97e-2)" "unprognostic (2.93e-2)" "unprognostic (9.01e-2)" "unprognostic (8.64e-3)" "unprognostic (8.55e-3)" "unprognostic (4.61e-3)" "unprognostic (4.27e-2)" "unprognostic (2.07e-1)" "validated prognostic unfavorable (2.90e-5)" "validated prognostic unfavorable (6.71e-7)" "unprognostic (1.34e-1)" "unprognostic (2.55e-2)" "unprognostic (2.08e-2)" "unprognostic (3.44e-1)" "unprognostic (3.48e-1)" "unprognostic (6.78e-2)" "unprognostic (9.78e-2)" "unprognostic (1.43e-2)" "unprognostic (2.94e-1)" "unprognostic (2.29e-1)" "unprognostic (1.80e-2)" "unprognostic (2.04e-2)" "unprognostic (2.40e-1)" "unprognostic (3.97e-2)" "unprognostic (9.21e-3)" "unprognostic (1.72e-1)" DDR1 "CAK, CD167, EDDR1, NEP, NTRK4, PTK3A, RTK6" ENSG00000204580 "Discoidin domain receptor tyrosine kinase 1" Q08345 6 30876421-30900156 "CD markers, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lactation, Pregnancy" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 91.8;Bergmann glia: 29.4;Distal convoluted tubule cells: 24.4;Ependymal cells: 101.0;Loop of henle epithelial cells: 36.4;Oligodendrocyte progenitor cells: 97.9;Oligodendrocytes: 78.5;Papillary tip epithelial cells: 51.8;Renal collecting duct intercalated cells: 51.8;Renal collecting duct principal cells: 49.2;Renal connecting tubule cells: 43.2" "Cell type enhanced" "Detected in all" "astrocyte: 116.1;ependymal cell: 130.3;oligodendrocyte: 97.1;oligodendrocyte precursor cell: 99.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010162, CAB025656, HPA074209" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" Receptor NA NA 15000000 "Cluster 68: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 13 "Plasma membrane" "Nucleoplasm, Cytosol" "CAB010162: , CAB025656: , HPA074209: " "unprognostic (1.77e-1)" "unprognostic (6.79e-2)" "unprognostic (1.26e-1)" "potential prognostic unfavorable (8.28e-4)" "unprognostic (2.87e-1)" "unprognostic (3.71e-2)" "unprognostic (2.62e-1)" "unprognostic (1.55e-1)" "unprognostic (2.91e-1)" "unprognostic (1.92e-1)" "potential prognostic favorable (3.80e-6)" "unprognostic (6.51e-3)" "unprognostic (1.57e-1)" "unprognostic (4.83e-2)" "unprognostic (5.38e-3)" "unprognostic (2.42e-1)" "unprognostic (2.06e-1)" "unprognostic (1.57e-1)" "unprognostic (4.65e-2)" "unprognostic (8.30e-2)" "unprognostic (2.82e-1)" "unprognostic (3.47e-2)" "unprognostic (3.66e-2)" "unprognostic (1.72e-1)" "unprognostic (3.57e-2)" "unprognostic (5.69e-3)" "unprognostic (3.57e-2)" "unprognostic (2.37e-1)" "unprognostic (2.59e-1)" "unprognostic (3.20e-2)" "unprognostic (4.63e-2)" DDR2 "NTRKR3, TKT, TYRO10" ENSG00000162733 "Discoidin domain receptor tyrosine kinase 2" Q16832 1 162631373-162787405 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Osteogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 304.7;Adrenal cortex cells: 741.1;Choroid plexus epithelial cells: 586.4;Endometrial stromal cells: 184.4;Fibro-adipogenic progenitors: 516.1;Fibroblasts: 366.1;Retinal pigment epithelial cells: 306.9" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 472.9;fibroblast: 253.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 44.3" "Adrenal gland - Adrenal cortex cells, Lung - Fibroblasts_1, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070112 Approved "Plasma membrane,Actin filaments" Yes No 490000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 103: Non-specific - Basic cellular processes" 37 "Plasma membrane, Actin filaments" "HPA070112: " "unprognostic (4.93e-3)" "unprognostic (5.52e-2)" "unprognostic (1.10e-2)" "unprognostic (6.72e-3)" "unprognostic (5.10e-2)" "unprognostic (1.04e-1)" "unprognostic (6.48e-2)" "unprognostic (3.25e-2)" "unprognostic (1.76e-1)" "unprognostic (1.71e-1)" "unprognostic (4.29e-3)" "unprognostic (5.27e-2)" "potential prognostic unfavorable (5.22e-7)" "unprognostic (2.74e-1)" "unprognostic (3.36e-2)" "unprognostic (1.89e-2)" "unprognostic (8.95e-2)" "unprognostic (1.63e-1)" "unprognostic (2.07e-1)" "unprognostic (5.31e-3)" "potential prognostic unfavorable (9.83e-6)" "unprognostic (1.68e-1)" "unprognostic (4.52e-2)" "unprognostic (1.59e-1)" "unprognostic (5.70e-2)" "unprognostic (1.48e-2)" "unprognostic (6.21e-2)" "unprognostic (3.94e-3)" "unprognostic (6.62e-2)" "unprognostic (3.10e-2)" "unprognostic (1.49e-1)" DDRGK1 "C20orf116, dJ1187M17.3, UFBP1" ENSG00000198171 "DDRGK domain containing 1" Q96HY6 20 3190350-3204685 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Heart muscle - Macrophages, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013373, HPA013705" Approved Supported "Nucleoli,Endoplasmic reticulum" NA NA 9100 "Cluster 29: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 53: Neurons - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 97: Non-specific - Cellular respiration" 84 "Endoplasmic reticulum" Nucleoli "HPA013373: , HPA013705: " "unprognostic (2.60e-1)" "unprognostic (3.87e-2)" "unprognostic (2.97e-1)" "unprognostic (4.63e-2)" "unprognostic (1.98e-1)" "unprognostic (3.12e-3)" "unprognostic (1.12e-2)" "unprognostic (9.33e-3)" "unprognostic (1.14e-1)" "unprognostic (3.32e-2)" "potential prognostic favorable (9.12e-4)" "unprognostic (6.76e-2)" "unprognostic (1.83e-2)" "unprognostic (3.15e-2)" "unprognostic (3.62e-2)" "unprognostic (3.81e-1)" "unprognostic (1.52e-1)" "unprognostic (2.06e-3)" "unprognostic (1.50e-1)" "unprognostic (4.02e-2)" "unprognostic (4.05e-1)" "unprognostic (4.98e-3)" "unprognostic (2.76e-3)" "unprognostic (4.53e-2)" "unprognostic (1.10e-1)" "unprognostic (2.40e-2)" "unprognostic (2.04e-1)" "unprognostic (1.06e-2)" "unprognostic (7.28e-2)" "unprognostic (6.86e-2)" "unprognostic (3.45e-2)" DDT "D-DT, DDCT, MIF-2, MIF2" ENSG00000099977 "D-dopachrome tautomerase" P30046 22 23970542-23980525 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Melanin biosynthesis" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1021.2" "Cell type enhanced" "Detected in many" "Enterocytes: 573.3;Hepatocytes: 3219.6;Parietal cells: 979.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes" "HPA049871, HPA074115" Enhanced Approved Mitochondria NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 27: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 93: Hepatocytes - Bile production & excretion" Mitochondria "HPA049871: , HPA074115: " "unprognostic (1.18e-1)" "unprognostic (8.77e-2)" "potential prognostic favorable (4.25e-4)" "unprognostic (1.82e-1)" "unprognostic (1.60e-2)" "unprognostic (1.44e-1)" "unprognostic (8.00e-2)" "unprognostic (2.53e-1)" "unprognostic (5.69e-3)" "unprognostic (5.93e-2)" "unprognostic (7.37e-3)" "unprognostic (1.44e-1)" "unprognostic (1.09e-1)" "potential prognostic favorable (8.71e-4)" "unprognostic (3.63e-1)" "unprognostic (1.79e-1)" "unprognostic (1.35e-2)" "unprognostic (1.03e-1)" "unprognostic (1.83e-1)" "unprognostic (4.00e-2)" "unprognostic (1.25e-1)" "unprognostic (9.65e-2)" "unprognostic (1.88e-1)" "unprognostic (5.48e-2)" "unprognostic (1.60e-2)" "unprognostic (3.63e-1)" "unprognostic (7.22e-2)" "unprognostic (3.43e-1)" "unprognostic (1.23e-1)" "unprognostic (1.64e-1)" "unprognostic (2.14e-2)" DDTL ENSG00000099974 "D-dopachrome tautomerase like" A6NHG4 22 23966888-23972556 "Predicted intracellular proteins" Lyase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "liver: 57.8" "Cell type enhanced" "Detected in some" "Epicardial cells: 2.3;Loop of henle epithelial cells: 1.0;Proximal tubule cells: 1.5;Renal collecting duct intercalated cells: 1.4;Renal connecting tubule cells: 1.3" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 10 "basophil: 1.0" "Lineage enriched" "Detected in single" 10 "granulocytes: 1.0" "Low cancer specificity" "Detected in some" HPA074115 Approved NA NA "Cluster 70: Non-specific - Protein processing" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" "HPA074115: " "unprognostic (1.16e-2)" "unprognostic (5.70e-2)" "unprognostic (1.76e-1)" "unprognostic (2.49e-2)" "unprognostic (1.15e-1)" "unprognostic (4.30e-1)" "unprognostic (1.85e-1)" "unprognostic (2.41e-1)" "unprognostic (4.55e-3)" "unprognostic (1.37e-1)" "unprognostic (2.78e-3)" "unprognostic (1.95e-2)" "unprognostic (1.98e-1)" "potential prognostic favorable (6.61e-4)" "unprognostic (8.23e-2)" "unprognostic (1.29e-1)" "unprognostic (1.68e-1)" "unprognostic (4.01e-2)" "unprognostic (5.33e-2)" "unprognostic (2.41e-1)" "unprognostic (1.44e-2)" "unprognostic (1.96e-2)" "unprognostic (2.19e-2)" "unprognostic (3.19e-1)" "unprognostic (1.83e-2)" "unprognostic (9.47e-2)" "unprognostic (8.27e-2)" "unprognostic (1.07e-1)" "unprognostic (2.12e-1)" "unprognostic (2.67e-3)" "unprognostic (2.58e-2)" DDX1 DBP-RB ENSG00000079785 "DEAD-box helicase 1" Q92499 2 15591178-15634346 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity, mRNA processing, Transcription, Transcription regulation, tRNA processing" "Activator, DNA-binding, Exonuclease, Helicase, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 303.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in all" 20 "Neuroblastoma: 4589.7" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012280, HPA034502, HPA034503" Enhanced Supported Nucleoplasm,Cytosol NA NA 35000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 17: Non-specific - RNA processing" 60 Nucleoplasm Cytosol "CAB012280: , HPA034502: , HPA034503: " "unprognostic (4.37e-2)" "unprognostic (7.21e-2)" "unprognostic (5.81e-2)" "unprognostic (2.54e-2)" "unprognostic (3.04e-1)" "unprognostic (1.92e-1)" "unprognostic (3.96e-2)" "unprognostic (7.57e-2)" "unprognostic (4.54e-2)" "unprognostic (2.93e-2)" "potential prognostic favorable (1.88e-8)" "unprognostic (6.20e-3)" "unprognostic (7.45e-2)" "validated prognostic unfavorable (1.65e-6)" "validated prognostic unfavorable (5.15e-6)" "unprognostic (2.28e-2)" "unprognostic (8.31e-2)" "unprognostic (4.43e-3)" "unprognostic (7.44e-2)" "unprognostic (1.11e-1)" "unprognostic (6.97e-2)" "unprognostic (8.86e-3)" "unprognostic (5.03e-2)" "unprognostic (1.18e-1)" "unprognostic (1.66e-1)" "unprognostic (5.23e-2)" "unprognostic (4.59e-2)" "unprognostic (2.16e-1)" "unprognostic (2.64e-1)" "unprognostic (2.99e-1)" "unprognostic (1.90e-1)" DDX10 "Dbp4, HRH-J8" ENSG00000178105 "DEAD-box helicase 10" Q13206 11 108665058-108940999 "Cancer-related genes, Enzymes, Essential proteins, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 354.0;Sertoli cells: 308.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" HPA004691 Approved Approved Nucleoli NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 61 Nucleoli "HPA004691: " "unprognostic (9.13e-3)" "unprognostic (4.68e-2)" "unprognostic (3.77e-1)" "unprognostic (7.37e-2)" "unprognostic (1.14e-1)" "unprognostic (4.58e-2)" "unprognostic (1.38e-1)" "unprognostic (6.91e-3)" "unprognostic (9.84e-3)" "unprognostic (1.15e-3)" "potential prognostic favorable (1.09e-5)" "unprognostic (1.31e-1)" "unprognostic (2.08e-1)" "unprognostic (1.92e-3)" "unprognostic (3.80e-3)" "unprognostic (9.96e-3)" "potential prognostic unfavorable (1.36e-5)" "unprognostic (1.80e-1)" "unprognostic (3.06e-1)" "unprognostic (3.10e-2)" "unprognostic (2.37e-1)" "potential prognostic unfavorable (1.29e-4)" "unprognostic (1.38e-2)" "unprognostic (1.55e-1)" "unprognostic (2.05e-2)" "unprognostic (1.33e-1)" "unprognostic (6.00e-2)" "unprognostic (2.18e-1)" "unprognostic (7.98e-2)" "unprognostic (2.04e-2)" "unprognostic (3.19e-2)" DDX11 "CHL1, ChlR1, KRG-2, WABS" ENSG00000013573 "DEAD/H-box helicase 11" Q96FC9 12 31073860-31104799 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, Host-virus interaction, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Helicase, Hydrolase, Isomerase, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 33.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 180.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA065197 Supported Enhanced Nucleoplasm,Nucleoli No Yes "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 6: Non-specific - Immune response" "Cluster 38: Non-specific - Transcription" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 2 Nucleoplasm Nucleoli "HPA065197: " "unprognostic (6.28e-2)" "unprognostic (1.06e-1)" "unprognostic (1.49e-1)" "unprognostic (1.26e-2)" "unprognostic (1.33e-2)" "unprognostic (9.87e-2)" "unprognostic (1.15e-1)" "potential prognostic favorable (1.56e-4)" "unprognostic (2.16e-3)" "unprognostic (2.39e-2)" "potential prognostic unfavorable (3.58e-6)" "unprognostic (5.42e-3)" "unprognostic (2.13e-1)" "validated prognostic unfavorable (1.28e-5)" "validated prognostic unfavorable (9.08e-4)" "unprognostic (1.37e-2)" "unprognostic (1.68e-1)" "unprognostic (4.03e-1)" "unprognostic (1.70e-1)" "unprognostic (2.41e-1)" "potential prognostic favorable (6.14e-4)" "unprognostic (3.13e-2)" "unprognostic (2.13e-3)" "unprognostic (4.77e-1)" "unprognostic (1.92e-3)" "unprognostic (2.87e-1)" "potential prognostic unfavorable (7.88e-5)" "unprognostic (2.14e-2)" "unprognostic (3.87e-2)" "unprognostic (2.48e-2)" "unprognostic (3.08e-2)" DDX17 P72 ENSG00000100201 "DEAD-box helicase 17" Q92841 22 38483438-38507660 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Immunity, mRNA processing, mRNA splicing, RNA-mediated gene silencing, rRNA processing, Transcription, Transcription regulation" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB024908, HPA063142" Supported Supported "Nuclear speckles" "Intracellular and membrane" Transcription NA NA 110000 "Cluster 35: Neutrophils - Protein binding" "Cluster 64: Non-specific - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 66: Non-specific - Mitochondria" "Cluster 7: Non-specific - Transcription" 123 "Nuclear speckles" "CAB024908: , HPA063142: " "unprognostic (1.79e-3)" "unprognostic (9.21e-2)" "unprognostic (7.17e-2)" "unprognostic (6.87e-2)" "unprognostic (1.49e-1)" "unprognostic (3.10e-1)" "unprognostic (3.77e-2)" "unprognostic (5.43e-2)" "unprognostic (1.01e-1)" "unprognostic (4.69e-3)" "unprognostic (7.20e-2)" "potential prognostic favorable (4.05e-4)" "unprognostic (9.45e-3)" "unprognostic (9.50e-3)" "unprognostic (1.81e-1)" "unprognostic (1.27e-1)" "unprognostic (7.02e-2)" "unprognostic (2.59e-3)" "unprognostic (3.30e-2)" "unprognostic (3.81e-1)" "unprognostic (3.68e-1)" "unprognostic (7.71e-2)" "unprognostic (1.27e-3)" "unprognostic (9.44e-2)" "unprognostic (3.38e-3)" "unprognostic (1.34e-1)" "unprognostic (1.27e-1)" "unprognostic (2.29e-1)" "unprognostic (3.12e-1)" "unprognostic (4.92e-2)" "unprognostic (1.02e-1)" DDX18 "Has1, MrDb" ENSG00000088205 "DEAD-box helicase 18" Q9NVP1 2 117814691-117832377 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035400, HPA041056" Approved Enhanced "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No 4200 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 20: Non-specific - Transcription regulation" 65 "Nucleoli, Nucleoli rim, Mitotic chromosome" "HPA035400: , HPA041056: " "unprognostic (2.11e-2)" "unprognostic (1.37e-1)" "unprognostic (9.03e-2)" "unprognostic (3.55e-2)" "unprognostic (7.32e-2)" "unprognostic (2.53e-2)" "unprognostic (1.24e-1)" "unprognostic (7.26e-2)" "unprognostic (5.94e-3)" "unprognostic (3.03e-2)" "potential prognostic favorable (5.66e-6)" "unprognostic (3.18e-3)" "unprognostic (2.13e-1)" "potential prognostic unfavorable (2.78e-4)" "unprognostic (8.91e-3)" "unprognostic (1.69e-2)" "unprognostic (3.47e-3)" "unprognostic (5.39e-2)" "unprognostic (2.20e-3)" "unprognostic (2.70e-1)" "unprognostic (7.51e-2)" "unprognostic (9.80e-3)" "unprognostic (4.21e-3)" "unprognostic (1.07e-1)" "unprognostic (3.16e-2)" "unprognostic (3.16e-2)" "unprognostic (7.74e-3)" "unprognostic (1.29e-1)" "unprognostic (4.99e-1)" "unprognostic (2.72e-2)" "unprognostic (5.36e-1)" DDX19A "DDX19L, FLJ11126" ENSG00000168872 "DEAD-box helicase 19A" Q9NUU7 16 70346861-70373383 "Enzymes, Predicted intracellular proteins, Transporters" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045252, HPA066668" Approved Uncertain Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 17: Non-specific - RNA processing" 10 Nucleoplasm "HPA045252: , HPA066668: " "unprognostic (3.72e-2)" "unprognostic (4.76e-3)" "unprognostic (2.48e-1)" "unprognostic (2.88e-1)" "unprognostic (4.05e-1)" "unprognostic (6.37e-2)" "unprognostic (2.15e-2)" "unprognostic (7.52e-2)" "unprognostic (5.63e-3)" "unprognostic (9.36e-3)" "potential prognostic favorable (3.55e-6)" "unprognostic (8.20e-2)" "unprognostic (8.08e-3)" "validated prognostic unfavorable (2.30e-6)" "validated prognostic unfavorable (9.41e-4)" "unprognostic (7.55e-2)" "unprognostic (4.30e-3)" "unprognostic (5.76e-2)" "unprognostic (4.91e-2)" "unprognostic (1.29e-1)" "unprognostic (1.53e-1)" "unprognostic (9.78e-2)" "unprognostic (6.87e-2)" "unprognostic (8.76e-2)" "unprognostic (4.00e-1)" "unprognostic (8.09e-2)" "unprognostic (5.79e-2)" "unprognostic (1.01e-1)" "unprognostic (2.84e-1)" "unprognostic (9.72e-2)" "unprognostic (1.44e-1)" DDX19B "DBP5, DDX19" ENSG00000157349 "DEAD-box helicase 19B" Q9UMR2 16 70289663-70335305 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 10.2;Enterocytes: 9.9;Gastric chief cells: 10.9;Late primary spermatocytes: 12.2;Tuft cells: 11.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037229, CAB037284, HPA046380, HPA066668" Approved Uncertain Nucleoplasm NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 39: Testis - Nuclear processes" "Cluster 2: Neurons - Nucleosome" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 15: Non-specific - Protein processing" 47 Nucleoplasm "CAB037229: , CAB037284: , HPA046380: , HPA066668: " "unprognostic (5.03e-3)" "unprognostic (2.71e-1)" "unprognostic (5.87e-2)" "unprognostic (3.73e-1)" "unprognostic (2.31e-2)" "unprognostic (4.48e-2)" "unprognostic (5.11e-2)" "unprognostic (2.05e-3)" "unprognostic (2.12e-2)" "unprognostic (2.12e-2)" "potential prognostic favorable (8.26e-8)" "unprognostic (1.01e-2)" "unprognostic (8.64e-3)" "unprognostic (2.25e-1)" "unprognostic (1.33e-3)" "unprognostic (3.80e-1)" "unprognostic (2.07e-2)" "unprognostic (2.99e-1)" "unprognostic (2.90e-1)" "unprognostic (1.41e-2)" "unprognostic (3.20e-2)" "unprognostic (2.09e-3)" "unprognostic (4.04e-1)" "unprognostic (1.03e-1)" "unprognostic (1.57e-2)" "unprognostic (2.07e-1)" "unprognostic (6.13e-2)" "unprognostic (3.39e-1)" "unprognostic (2.72e-1)" "unprognostic (3.86e-2)" "unprognostic (3.02e-1)" DDX20 "DP103, GEMIN3" ENSG00000064703 "DEAD-box helicase 20" Q9UHI6 1 111754832-111775602 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "testis: 38.3" "Group enriched" "Detected in many" 6 "Early spermatids: 815.0;Late primary spermatocytes: 480.9;Late spermatids: 1199.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005516, CAB015427" Enhanced Enhanced "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 57: Testis - Spermatogenesis" "Cluster 51: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 79 "Nuclear bodies" "Nucleoplasm, Cytosol" "CAB015427: , HPA005516: " "unprognostic (4.99e-2)" "unprognostic (5.79e-2)" "unprognostic (1.76e-1)" "unprognostic (7.98e-2)" "unprognostic (2.60e-2)" "unprognostic (1.22e-3)" "unprognostic (1.07e-1)" "unprognostic (1.08e-2)" "unprognostic (8.35e-2)" "potential prognostic favorable (1.22e-9)" "unprognostic (1.46e-1)" "unprognostic (3.06e-1)" "unprognostic (7.24e-2)" "unprognostic (2.11e-1)" "unprognostic (1.03e-2)" "unprognostic (5.61e-2)" "unprognostic (5.00e-2)" "unprognostic (1.29e-1)" "unprognostic (1.50e-1)" "unprognostic (4.80e-2)" "unprognostic (1.25e-1)" "unprognostic (1.85e-1)" "potential prognostic favorable (2.46e-4)" "unprognostic (6.71e-2)" "unprognostic (5.97e-2)" "unprognostic (2.47e-1)" "unprognostic (4.20e-1)" "unprognostic (9.32e-3)" "unprognostic (1.13e-2)" DDX21 "GURDB, RH-II/GU" ENSG00000165732 "DExD-box helicase 21" Q9NR30 10 68956135-68985068 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity, rRNA processing, Transcription" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 574.0;Suprabasal keratinocytes: 576.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036592, HPA036593" Enhanced Enhanced "Nucleoplasm,Nucleoli rim,Mitotic chromosome" Yes No 370000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 21: Non-specific - Metabolism" "Cluster 52: Non-specific - Mitochondria" "Cluster 17: Non-specific - RNA processing" 345 "Nucleoli rim, Mitotic chromosome" Nucleoplasm "HPA036592: , HPA036593: " "unprognostic (9.67e-2)" "unprognostic (2.05e-1)" "unprognostic (7.85e-2)" "unprognostic (1.64e-3)" "unprognostic (8.88e-2)" "unprognostic (2.16e-1)" "unprognostic (2.40e-2)" "potential prognostic favorable (1.22e-4)" "unprognostic (2.83e-2)" "unprognostic (1.32e-2)" "potential prognostic favorable (1.49e-4)" "unprognostic (4.15e-1)" "unprognostic (1.45e-3)" "unprognostic (5.60e-3)" "unprognostic (2.12e-2)" "unprognostic (1.66e-2)" "unprognostic (2.51e-3)" "unprognostic (3.41e-1)" "unprognostic (1.26e-1)" "unprognostic (1.49e-1)" "unprognostic (2.01e-3)" "potential prognostic unfavorable (8.28e-4)" "unprognostic (1.01e-1)" "unprognostic (4.74e-2)" "unprognostic (1.96e-2)" "unprognostic (4.34e-2)" "unprognostic (1.03e-1)" "unprognostic (1.75e-1)" "unprognostic (8.87e-2)" "unprognostic (5.95e-3)" "unprognostic (1.38e-1)" DDX23 "prp28, PRPF28, SNRNP100, U5-100KD" ENSG00000174243 "DEAD-box helicase 23" Q9BUQ8 12 48829756-48852842 "Enzymes, Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038680, HPA039037" Approved Supported Nucleoplasm,Nucleoli NA NA 11000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 81 "Nucleoplasm, Nucleoli" "HPA038680: , HPA039037: " "unprognostic (1.62e-1)" "unprognostic (2.07e-3)" "unprognostic (1.04e-1)" "unprognostic (4.70e-2)" "unprognostic (2.19e-1)" "unprognostic (1.77e-1)" "unprognostic (4.74e-1)" "unprognostic (8.54e-2)" "unprognostic (2.15e-1)" "unprognostic (5.30e-3)" "potential prognostic favorable (2.32e-4)" "unprognostic (2.32e-3)" "unprognostic (1.59e-1)" "potential prognostic unfavorable (9.57e-6)" "unprognostic (5.63e-3)" "potential prognostic unfavorable (1.54e-4)" "unprognostic (4.26e-3)" "unprognostic (2.50e-2)" "unprognostic (3.16e-1)" "unprognostic (2.02e-1)" "unprognostic (8.22e-2)" "unprognostic (2.10e-1)" "unprognostic (2.10e-2)" "unprognostic (1.40e-1)" "unprognostic (1.13e-1)" "unprognostic (5.05e-3)" "unprognostic (6.40e-2)" "unprognostic (1.78e-1)" "unprognostic (1.00e-1)" "unprognostic (3.24e-1)" "unprognostic (7.43e-3)" DDX24 ENSG00000089737 "DEAD-box helicase 24" Q9GZR7 14 94048287-94081202 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 159.5;Brain inhibitory neurons: 168.5;Other brain neurons: 271.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 7.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002554 Uncertain Approved Nucleoli,Cytosol NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 98: Neurons - Neurotransmission & signaling" 138 "Nucleoli, Cytosol" "HPA002554: " "unprognostic (1.44e-1)" "unprognostic (1.66e-1)" "unprognostic (6.18e-2)" "unprognostic (8.79e-2)" "unprognostic (1.41e-1)" "unprognostic (2.37e-1)" "unprognostic (1.69e-1)" "unprognostic (4.35e-2)" "unprognostic (2.45e-2)" "unprognostic (5.01e-2)" "unprognostic (3.70e-3)" "unprognostic (6.41e-2)" "unprognostic (1.66e-2)" "unprognostic (2.81e-2)" "unprognostic (1.06e-1)" "unprognostic (7.34e-2)" "unprognostic (3.83e-1)" "potential prognostic favorable (1.75e-5)" "unprognostic (6.54e-2)" "unprognostic (2.35e-2)" "unprognostic (4.30e-3)" "unprognostic (1.18e-3)" "unprognostic (7.19e-2)" "unprognostic (2.96e-1)" "unprognostic (6.82e-2)" "unprognostic (1.62e-2)" "unprognostic (2.50e-2)" "unprognostic (8.77e-2)" "unprognostic (1.27e-1)" "unprognostic (1.84e-1)" "unprognostic (2.43e-2)" DDX25 GRTH ENSG00000109832 "DEAD-box helicase 25" Q9UHL0 11 125903348-125943702 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Differentiation, mRNA transport, Spermatogenesis, Translation regulation, Transport" "Developmental protein, Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 21.8;retina: 20.2;testis: 85.4" "Group enriched" "Detected in many" 4 "Early spermatids: 297.3;Epicardial cells: 352.5;Late primary spermatocytes: 626.8" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 8.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 5.9" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Pancreas - Alpha cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020137 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 67: Testis - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 24: Non-specific - Unknown function" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 2 Nucleoplasm Cytosol "HPA020137: " "unprognostic (2.37e-1)" "unprognostic (3.83e-3)" "unprognostic (1.78e-2)" "unprognostic (1.72e-1)" "unprognostic (4.02e-1)" "unprognostic (2.29e-3)" "potential prognostic unfavorable (6.01e-6)" "unprognostic (1.11e-1)" "unprognostic (9.61e-2)" "unprognostic (2.06e-2)" DDX27 "dJ686N3.1, DRS1" ENSG00000124228 "DEAD-box helicase 27" 20 49219347-49244077 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 201.3;Late spermatids: 187.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047087, HPA053455" Approved Approved Nucleoli NA No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 54: Non-specific - Ribosome" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 62: Non-specific - Plasma proteins" "Cluster 103: Non-specific - Basic cellular processes" 36 Nucleoli "HPA047087: , HPA053455: " "unprognostic (7.78e-2)" "unprognostic (4.51e-1)" "unprognostic (1.23e-1)" "unprognostic (1.57e-1)" "unprognostic (3.37e-2)" "unprognostic (1.69e-1)" "unprognostic (2.84e-1)" "unprognostic (1.73e-2)" "unprognostic (2.63e-2)" "unprognostic (2.13e-3)" "unprognostic (9.56e-3)" "unprognostic (8.05e-2)" "unprognostic (1.51e-1)" "validated prognostic unfavorable (7.92e-8)" "validated prognostic unfavorable (1.17e-4)" "unprognostic (2.91e-2)" "potential prognostic unfavorable (1.88e-4)" "unprognostic (1.38e-1)" "unprognostic (1.11e-1)" "unprognostic (7.64e-3)" "unprognostic (7.77e-2)" "unprognostic (1.64e-2)" "potential prognostic unfavorable (6.42e-5)" "unprognostic (6.68e-3)" "unprognostic (4.83e-3)" "unprognostic (5.93e-3)" "unprognostic (4.99e-1)" "unprognostic (9.97e-2)" "unprognostic (3.31e-1)" "unprognostic (1.89e-1)" "unprognostic (9.82e-2)" DDX28 "FLJ11282, MDDX28" ENSG00000182810 "DEAD-box helicase 28" Q9NUL7 16 68020916-68023232 "Enzymes, Predicted intracellular proteins" "Ribosome biogenesis" "Helicase, Hydrolase, RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 33.1;Esophageal basal cells: 24.9;Migrating cytotrophoblasts: 24.7;Syncytiotrophoblasts: 121.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Pancreas - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041911, HPA053585" Approved Supported Nucleoli,Mitochondria,Cytosol No No "Cluster 3: Non-specific - Nuclear processes" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 53 Mitochondria "Nucleoli, Cytosol" "HPA041911: , HPA053585: " "unprognostic (3.53e-2)" "unprognostic (7.99e-2)" "unprognostic (2.83e-2)" "unprognostic (2.12e-2)" "unprognostic (2.23e-2)" "unprognostic (5.90e-2)" "unprognostic (2.18e-1)" "potential prognostic favorable (8.49e-4)" "unprognostic (1.68e-2)" "unprognostic (1.40e-2)" "potential prognostic favorable (2.07e-4)" "unprognostic (9.43e-2)" "potential prognostic favorable (3.55e-4)" "unprognostic (3.80e-2)" "unprognostic (3.74e-1)" "unprognostic (8.51e-2)" "unprognostic (1.97e-1)" "unprognostic (9.75e-3)" "unprognostic (2.26e-2)" "unprognostic (1.47e-1)" "unprognostic (1.77e-1)" "unprognostic (3.20e-2)" "unprognostic (1.30e-2)" "unprognostic (7.34e-3)" "unprognostic (4.24e-3)" "unprognostic (2.03e-1)" "unprognostic (3.25e-1)" "unprognostic (7.95e-2)" "unprognostic (9.97e-2)" "unprognostic (6.12e-2)" "unprognostic (1.88e-1)" DDX31 "FLJ13633, FLJ14578, FLJ23349, PPP1R25" ENSG00000125485 "DEAD-box helicase 31" Q9H8H2 9 132592997-132670401 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase, Isomerase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020891 Supported "Nucleoli,Golgi apparatus,Vesicles" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 64: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 94: Gonadal somatic cells - Mixed function" 59 Nucleoli "Golgi apparatus, Vesicles" "HPA020891: " "unprognostic (2.88e-2)" "unprognostic (1.83e-2)" "unprognostic (2.72e-1)" "unprognostic (9.68e-2)" "unprognostic (2.27e-1)" "unprognostic (2.03e-2)" "unprognostic (7.04e-2)" "unprognostic (1.34e-3)" "unprognostic (7.45e-2)" "unprognostic (3.00e-1)" "potential prognostic favorable (1.86e-4)" "unprognostic (3.47e-3)" "unprognostic (1.07e-3)" "unprognostic (1.89e-3)" "unprognostic (6.25e-2)" "unprognostic (3.74e-1)" "unprognostic (1.24e-2)" "unprognostic (8.36e-2)" "unprognostic (1.79e-2)" "unprognostic (1.03e-1)" "unprognostic (2.39e-1)" "unprognostic (3.72e-1)" "unprognostic (1.08e-2)" "unprognostic (6.74e-2)" "unprognostic (4.20e-3)" "unprognostic (7.31e-2)" "unprognostic (1.96e-2)" "unprognostic (2.18e-2)" "unprognostic (1.92e-1)" "unprognostic (1.71e-1)" "unprognostic (1.50e-1)" DDX39A "BAT1L, DDX39, DDXL, URH49" ENSG00000123136 "DExD-box helicase 39A" O00148 19 14408798-14419383 "Enzymes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 155.6" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 226.7;Early spermatids: 288.1;Esophageal basal cells: 179.1;Late primary spermatocytes: 529.6;Late spermatids: 380.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055334 Approved Approved "Nuclear speckles" NA NA 270000 "Cluster 33: Non-specific - ATP binding" "Cluster 39: Testis - Nuclear processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 27: Non-specific - Cell proliferation" 43 "Nuclear speckles" "HPA055334: " "unprognostic (2.48e-1)" "unprognostic (1.69e-1)" "unprognostic (2.23e-3)" "unprognostic (2.09e-1)" "unprognostic (4.19e-2)" "unprognostic (2.45e-1)" "unprognostic (2.13e-1)" "unprognostic (8.32e-2)" "unprognostic (2.35e-2)" "unprognostic (9.03e-3)" "unprognostic (6.19e-3)" "unprognostic (3.05e-3)" "potential prognostic unfavorable (4.68e-4)" "unprognostic (2.24e-3)" "unprognostic (1.85e-3)" "potential prognostic unfavorable (7.78e-4)" "unprognostic (1.01e-1)" "unprognostic (3.15e-2)" "unprognostic (9.60e-2)" "unprognostic (4.89e-2)" "unprognostic (3.33e-2)" "unprognostic (1.18e-1)" "unprognostic (1.37e-2)" "unprognostic (2.95e-1)" "unprognostic (2.28e-2)" "unprognostic (8.34e-2)" "unprognostic (1.77e-2)" "unprognostic (3.03e-1)" "unprognostic (2.36e-2)" "unprognostic (2.77e-1)" DDX39B "BAT1, D6S81E, UAP56" ENSG00000198563 "DExD-box helicase 39B" Q13838 6 31530219-31542448 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "mRNA processing, mRNA splicing, mRNA transport, Transport" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 10 "Astrocytes: 85.3;Bergmann glia: 82.2;Brain excitatory neurons: 54.4;Brain inhibitory neurons: 48.5;Choroid plexus epithelial cells: 86.9;Ependymal cells: 54.9;Microglia: 79.2;Oligodendrocyte progenitor cells: 84.8;Oligodendrocytes: 70.6;Other brain neurons: 45.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034012, HPA055334, HPA058450" Enhanced Enhanced "Nuclear speckles" NA NA 540000 "Cluster 33: Non-specific - ATP binding" "Cluster 64: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 22: Non-specific - Basic cellular functions" 193 "Nuclear speckles" "CAB034012: , HPA055334: , HPA058450: " "unprognostic (5.79e-3)" "unprognostic (1.47e-2)" "unprognostic (2.69e-1)" "unprognostic (2.66e-1)" "unprognostic (1.11e-1)" "unprognostic (2.70e-3)" "unprognostic (1.04e-1)" "unprognostic (9.45e-2)" "unprognostic (3.49e-1)" "potential prognostic favorable (8.75e-5)" "unprognostic (2.00e-2)" "unprognostic (1.47e-1)" "unprognostic (1.39e-3)" "unprognostic (4.45e-2)" "unprognostic (1.20e-1)" "unprognostic (4.78e-2)" "unprognostic (1.82e-1)" "unprognostic (1.32e-1)" "unprognostic (5.97e-2)" "potential prognostic favorable (9.33e-4)" "unprognostic (1.32e-1)" "unprognostic (5.84e-3)" "unprognostic (4.29e-2)" "unprognostic (6.43e-2)" "unprognostic (3.69e-2)" "unprognostic (4.95e-2)" "unprognostic (1.81e-1)" "unprognostic (2.58e-1)" "unprognostic (2.50e-1)" "unprognostic (2.00e-1)" DDX3X "CAP-Rf, DBX, DDX14, DDX3, HLP2" ENSG00000215301 "DEAD-box helicase 3 X-linked" O00571 X 41333348-41364472 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Chromosome partition, Host-virus interaction, Immunity, Innate immunity, Ribosome biogenesis, Transcription, Transcription regulation, Translation regulation" "DNA-binding, Helicase, Hydrolase, RNA-binding" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 1604.6;Neutrophils: 1079.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001648, HPA005631, HPA059585" Supported Supported Approved "Plasma membrane,Cytosol" NA NA 120000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 36: Non-specific - mRNA processing" "Cluster 20: Non-specific - Transcription regulation" 112 Cytosol "Plasma membrane" "HPA001648: , HPA005631: , HPA059585: " "unprognostic (1.51e-1)" "unprognostic (1.04e-2)" "unprognostic (3.85e-1)" "unprognostic (5.89e-2)" "unprognostic (1.21e-3)" "unprognostic (9.44e-2)" "unprognostic (3.28e-1)" "unprognostic (3.60e-3)" "unprognostic (2.73e-2)" "unprognostic (6.15e-3)" "potential prognostic favorable (4.07e-6)" "unprognostic (1.25e-2)" "unprognostic (9.71e-2)" "unprognostic (4.28e-2)" "unprognostic (8.86e-2)" "unprognostic (3.51e-2)" "unprognostic (7.79e-2)" "unprognostic (8.41e-2)" "unprognostic (1.56e-1)" "unprognostic (1.23e-2)" "unprognostic (5.01e-3)" "unprognostic (6.02e-3)" "unprognostic (2.79e-1)" "unprognostic (4.20e-1)" "potential prognostic favorable (9.09e-4)" "unprognostic (5.28e-2)" "unprognostic (5.14e-2)" "unprognostic (1.92e-1)" "unprognostic (2.00e-1)" "unprognostic (2.15e-1)" "unprognostic (1.70e-1)" DDX3Y DBY ENSG00000067048 "DEAD-box helicase 3 Y-linked" O15523 Y 12904108-12920478 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA-binding, Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 90.4" "Cell type enhanced" "Detected in many" "Early spermatids: 307.2;Hematopoietic stem cells: 270.3;Late spermatids: 1005.1;Megakaryocyte-Erythroid progenitors: 211.8;Neutrophils: 257.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 140.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001648, HPA005631, HPA059583" Enhanced Supported Supported "Plasma membrane,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 47: Leukemia - Hemostasis" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 20 Cytosol "Plasma membrane" "HPA001648: , HPA005631: , HPA059583: " "unprognostic (7.46e-2)" "unprognostic (2.77e-2)" "unprognostic (7.96e-2)" "unprognostic (2.33e-1)" "unprognostic (5.31e-2)" "potential prognostic favorable (1.01e-4)" "unprognostic (2.03e-1)" "unprognostic (4.42e-2)" "unprognostic (1.00e-1)" "unprognostic (7.99e-2)" "unprognostic (4.49e-2)" "unprognostic (1.06e-2)" "unprognostic (2.71e-1)" "unprognostic (2.94e-1)" "unprognostic (7.99e-2)" "unprognostic (4.69e-1)" "unprognostic (8.77e-2)" "unprognostic (2.94e-1)" "unprognostic (7.38e-2)" "unprognostic (3.36e-2)" "unprognostic (1.20e-2)" "unprognostic (7.09e-2)" "unprognostic (1.71e-2)" "unprognostic (5.53e-1)" "unprognostic (1.70e-2)" DDX4 VASA ENSG00000152670 "DEAD-box helicase 4" Q9NQI0 5 55738017-55817157 "Enzymes, Predicted intracellular proteins" "Differentiation, Meiosis, RNA-mediated gene silencing, Spermatogenesis" "Developmental protein, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 113 "testis: 139.8" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 129.4;Early primary spermatocytes: 289.6;Early spermatids: 700.2;Late primary spermatocytes: 676.5;Late spermatids: 240.8;Oocytes: 138.2;Respiratory ionocytes: 109.2;Undifferentiated spermatogonia: 168.9" "Cell type enhanced" "Detected in many" "oligodendrocyte: 14.2" "Cancer enriched" "Detected in single" 40 "Testicular Germ Cell Tumor (TCGA): 7.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Minor Salivary Gland - Minor salivary gland ductal cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB026170, HPA037763, HPA037764" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 9: Non-specific - Receptor signaling" "Cluster 59: Leukemia - T-cell receptor" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" "Nucleoplasm, Plasma membrane, Cytosol" "CAB026170: , HPA037763: , HPA037764: " "unprognostic (9.65e-2)" DDX41 "ABS, MGC8828" ENSG00000183258 "DEAD-box helicase 41" Q9UJV9 5 177511577-177516961 "Disease related genes, Enzymes, Essential proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal suprabasal cells: 64.5;Extravillous trophoblasts: 80.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017911, HPA048803" Supported Supported Nucleoplasm,Nucleoli NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 97: Non-specific - Cellular respiration" 29 Nucleoplasm Nucleoli "HPA017911: , HPA048803: " "unprognostic (1.90e-2)" "unprognostic (2.14e-2)" "unprognostic (9.18e-2)" "potential prognostic unfavorable (9.78e-4)" "unprognostic (1.17e-1)" "unprognostic (8.71e-2)" "unprognostic (8.76e-2)" "unprognostic (9.23e-2)" "potential prognostic unfavorable (8.08e-5)" "unprognostic (7.69e-2)" "potential prognostic favorable (4.89e-6)" "unprognostic (2.97e-1)" "unprognostic (2.54e-2)" "unprognostic (3.64e-2)" "unprognostic (7.69e-3)" "unprognostic (7.83e-3)" "unprognostic (1.07e-3)" "unprognostic (5.23e-3)" "unprognostic (2.77e-1)" "unprognostic (1.71e-1)" "unprognostic (1.88e-1)" "unprognostic (2.19e-2)" "unprognostic (2.14e-1)" "unprognostic (3.25e-2)" "unprognostic (6.92e-2)" "unprognostic (2.69e-1)" "unprognostic (1.70e-1)" "unprognostic (1.79e-1)" "unprognostic (7.60e-2)" "unprognostic (1.37e-1)" "unprognostic (1.76e-1)" DDX42 "RHELP, RNAHP, SF3b125, SF3B8" ENSG00000198231 "DEAD-box helicase 42" Q86XP3 17 63773603-63819317 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023447, HPA023571, HPA025941" Approved Enhanced "Nuclear speckles" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 17: Non-specific - RNA processing" 64 "Nuclear speckles" "HPA023447: , HPA023571: , HPA025941: " "unprognostic (1.70e-1)" "unprognostic (7.21e-2)" "unprognostic (2.54e-1)" "unprognostic (1.14e-2)" "unprognostic (6.18e-2)" "unprognostic (8.76e-3)" "unprognostic (5.77e-2)" "unprognostic (1.14e-2)" "unprognostic (1.12e-1)" "unprognostic (7.36e-3)" "potential prognostic favorable (7.29e-5)" "unprognostic (5.46e-3)" "unprognostic (3.14e-2)" "unprognostic (5.10e-2)" "unprognostic (2.82e-3)" "unprognostic (1.27e-1)" "unprognostic (1.19e-3)" "unprognostic (2.30e-1)" "unprognostic (2.39e-2)" "unprognostic (1.28e-2)" "unprognostic (6.66e-2)" "unprognostic (2.47e-2)" "unprognostic (6.93e-2)" "unprognostic (6.39e-2)" "unprognostic (7.88e-2)" "unprognostic (1.51e-1)" "unprognostic (1.99e-1)" "unprognostic (2.28e-1)" "unprognostic (1.30e-1)" "unprognostic (2.64e-2)" "unprognostic (2.01e-1)" DDX43 "CT13, DKFZp434H2114, HAGE" ENSG00000080007 "DEAD-box helicase 43" Q9NXZ2 6 73394828-73417566 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "placenta: 4.6;testis: 18.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 28.9;Differentiating spermatogonia: 47.4;Early primary spermatocytes: 50.3;Late primary spermatocytes: 62.3;Oocytes: 96.7;Undifferentiated spermatogonia: 80.6" "Cell type enhanced" "Detected in many" "fibroblast: 9.0" "Cancer enriched" "Detected in many" 14 "Testicular Germ Cell Tumor (TCGA): 20.1" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 8.7" "Testis - Spermatocytes" HPA031381 Enhanced NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 49: Hindbrain - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 5 "HPA031381: " "unprognostic (9.20e-3)" "unprognostic (4.68e-2)" "unprognostic (2.23e-2)" "unprognostic (2.44e-1)" "unprognostic (3.19e-2)" "unprognostic (9.02e-2)" "unprognostic (1.21e-1)" "unprognostic (8.03e-2)" "unprognostic (3.33e-1)" "unprognostic (4.36e-1)" "unprognostic (2.49e-1)" "unprognostic (2.64e-1)" "unprognostic (3.05e-1)" "unprognostic (1.13e-1)" "unprognostic (6.91e-2)" "unprognostic (1.09e-1)" DDX46 "FLJ25329, KIAA0801, Prp5, PRPF5" ENSG00000145833 "DEAD-box helicase 46" Q7L014 5 134758771-134855133 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036554, HPA057501" Supported Supported "Nucleoli fibrillar center,Nuclear speckles" NA NA 44000 "Cluster 22: Eosinophils - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 17: Non-specific - RNA processing" 25 "Nuclear speckles" "Nucleoli fibrillar center" "HPA036554: , HPA057501: " "unprognostic (6.94e-2)" "unprognostic (1.05e-1)" "unprognostic (2.84e-1)" "unprognostic (1.27e-1)" "unprognostic (2.59e-2)" "unprognostic (4.38e-2)" "unprognostic (2.08e-2)" "unprognostic (1.71e-1)" "unprognostic (7.50e-2)" "potential prognostic unfavorable (1.28e-4)" "potential prognostic favorable (1.81e-7)" "unprognostic (7.72e-3)" "unprognostic (3.40e-1)" "unprognostic (3.06e-3)" "unprognostic (9.23e-2)" "unprognostic (1.72e-1)" "unprognostic (4.67e-2)" "unprognostic (2.59e-2)" "unprognostic (1.42e-1)" "unprognostic (3.77e-1)" "unprognostic (1.07e-2)" "unprognostic (1.95e-2)" "unprognostic (8.29e-3)" "unprognostic (1.30e-2)" "unprognostic (1.06e-2)" "unprognostic (4.00e-2)" "unprognostic (1.64e-1)" "unprognostic (7.06e-2)" "unprognostic (2.79e-1)" "unprognostic (1.68e-2)" "unprognostic (1.14e-1)" DDX47 "DKFZp564O176, FLJ30012, HQ0256, RRP3" ENSG00000213782 "DEAD-box helicase 47" Q9H0S4 12 12813316-12829981 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, mRNA processing, mRNA splicing, rRNA processing" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 10.1;Bergmann glia: 11.7;Brain excitatory neurons: 10.2;Brain inhibitory neurons: 9.7;Choroid plexus epithelial cells: 11.7;Enteric stem cells: 7.6;Ependymal cells: 9.2;Microglia: 18.2;Oligodendrocyte progenitor cells: 13.2;Oligodendrocytes: 15.7;Other brain neurons: 9.4;Paneth cells: 15.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014855 Approved Supported Nucleoli NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 38: Non-specific - Transcription" "Cluster 22: Non-specific - Basic cellular functions" 15 Nucleoli "HPA014855: " "unprognostic (3.51e-1)" "unprognostic (9.64e-2)" "unprognostic (2.36e-1)" "unprognostic (4.55e-2)" "unprognostic (1.06e-1)" "unprognostic (5.21e-2)" "unprognostic (1.31e-1)" "unprognostic (1.06e-3)" "unprognostic (4.92e-3)" "unprognostic (1.02e-3)" "potential prognostic favorable (1.89e-4)" "unprognostic (1.12e-1)" "unprognostic (6.03e-2)" "potential prognostic unfavorable (3.57e-7)" "unprognostic (1.58e-3)" "potential prognostic unfavorable (4.34e-4)" "unprognostic (3.28e-3)" "unprognostic (5.73e-2)" "unprognostic (1.54e-2)" "unprognostic (2.66e-2)" "unprognostic (1.10e-1)" "unprognostic (2.49e-3)" "potential prognostic unfavorable (1.73e-4)" "unprognostic (1.89e-1)" "unprognostic (9.33e-2)" "unprognostic (2.12e-1)" "unprognostic (1.52e-1)" "unprognostic (1.65e-1)" "unprognostic (3.23e-1)" "unprognostic (1.07e-1)" "unprognostic (1.09e-1)" DDX49 "Dbp8, FLJ10432" ENSG00000105671 "DEAD-box helicase 49" Q9Y6V7 19 18919705-18929189 "Enzymes, Essential proteins, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 184.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041870, HPA048093" Enhanced Approved Mitochondria NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 24: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 10 Mitochondria "HPA041870: , HPA048093: " "unprognostic (3.23e-2)" "unprognostic (7.65e-2)" "unprognostic (3.41e-1)" "unprognostic (1.12e-2)" "unprognostic (2.27e-1)" "unprognostic (1.19e-1)" "unprognostic (3.44e-1)" "unprognostic (2.92e-1)" "unprognostic (8.60e-2)" "potential prognostic unfavorable (1.69e-4)" "unprognostic (4.76e-3)" "unprognostic (2.69e-1)" "unprognostic (1.35e-1)" "potential prognostic unfavorable (6.28e-6)" "unprognostic (1.33e-2)" "unprognostic (3.02e-2)" "unprognostic (4.79e-2)" "unprognostic (1.59e-2)" "unprognostic (5.38e-2)" "unprognostic (5.51e-2)" "unprognostic (1.58e-1)" "unprognostic (7.35e-2)" "unprognostic (2.50e-1)" "unprognostic (2.42e-3)" "unprognostic (6.79e-2)" "potential prognostic favorable (1.37e-4)" "unprognostic (4.62e-3)" "unprognostic (5.60e-2)" "unprognostic (2.85e-1)" "unprognostic (6.13e-2)" "unprognostic (1.08e-1)" DDX5 "G17P1, HLR1, p68" ENSG00000108654 "DEAD-box helicase 5" P17844 17 64498254-64508199 "Cancer-related genes, Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Helicase, Hydrolase, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005868, HPA020043, HPA071154" Supported Supported Nucleoplasm,Nucleoli No No 180000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 61: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Breast cancer - Unknown function" "Cluster 20: Non-specific - Transcription regulation" 194 "Nucleoplasm, Nucleoli" "CAB005868: , HPA020043: , HPA071154: " "unprognostic (1.16e-2)" "unprognostic (9.27e-2)" "unprognostic (1.75e-1)" "unprognostic (5.77e-3)" "unprognostic (3.08e-2)" "unprognostic (2.52e-1)" "unprognostic (8.23e-2)" "unprognostic (4.53e-1)" "unprognostic (2.13e-1)" "unprognostic (5.90e-2)" "validated prognostic favorable (3.05e-10)" "validated prognostic favorable (3.51e-4)" "unprognostic (1.15e-1)" "unprognostic (2.08e-1)" "unprognostic (1.12e-1)" "unprognostic (1.93e-1)" "unprognostic (1.22e-1)" "unprognostic (5.72e-2)" "unprognostic (1.50e-1)" "unprognostic (1.78e-1)" "unprognostic (1.86e-1)" "unprognostic (8.86e-2)" "potential prognostic unfavorable (1.59e-4)" "unprognostic (7.38e-2)" "unprognostic (7.31e-2)" "potential prognostic favorable (1.91e-4)" "unprognostic (1.27e-1)" "unprognostic (4.34e-2)" "unprognostic (1.49e-1)" "unprognostic (7.88e-2)" "unprognostic (6.67e-2)" DDX50 "GU2, GUB, MGC3199, RH-II/GuB" ENSG00000107625 "DExD-box helicase 50" Q9BQ39 10 68901286-68946847 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037388, HPA037389, HPA058196" Approved Enhanced Nucleoli NA NA 66000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 39: Testis - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 7: Non-specific - Transcription" 86 Nucleoli "HPA037388: , HPA037389: , HPA058196: " "unprognostic (3.70e-1)" "unprognostic (5.82e-2)" "unprognostic (2.08e-1)" "unprognostic (2.74e-1)" "unprognostic (1.77e-1)" "unprognostic (3.30e-2)" "unprognostic (1.23e-1)" "potential prognostic favorable (6.72e-6)" "unprognostic (9.21e-2)" "unprognostic (2.44e-1)" "potential prognostic favorable (4.92e-5)" "unprognostic (1.07e-2)" "unprognostic (7.99e-3)" "potential prognostic unfavorable (5.36e-4)" "unprognostic (3.21e-3)" "unprognostic (2.81e-1)" "unprognostic (1.20e-2)" "unprognostic (2.18e-1)" "unprognostic (7.38e-2)" "unprognostic (1.01e-1)" "potential prognostic unfavorable (1.07e-4)" "unprognostic (5.95e-2)" "unprognostic (4.00e-2)" "unprognostic (1.48e-1)" "unprognostic (4.57e-2)" "unprognostic (1.20e-1)" "unprognostic (2.58e-1)" "unprognostic (5.33e-2)" "unprognostic (2.86e-1)" "unprognostic (3.10e-2)" "unprognostic (1.85e-1)" DDX51 ENSG00000185163 "DEAD-box helicase 51" Q8N8A6 12 132136594-132144319 "Enzymes, Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 10.7;Bergmann glia: 8.8;Brain excitatory neurons: 19.5;Brain inhibitory neurons: 19.8;Distal convoluted tubule cells: 8.8;Ependymal cells: 8.1;Loop of henle epithelial cells: 9.8;Microglia: 8.5;Oligodendrocyte progenitor cells: 9.2;Oligodendrocytes: 12.6;Other brain neurons: 11.7;Podocytes: 7.2;Proximal tubule cells: 10.6;Renal collecting duct intercalated cells: 9.1;Renal collecting duct principal cells: 8.5;Renal connecting tubule cells: 10.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039503 Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 64: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 102: Non-specific - Mixed function" 19 "Nucleoplasm, Nucleoli" Cytosol "HPA039503: " "unprognostic (4.41e-2)" "unprognostic (1.77e-1)" "unprognostic (4.28e-1)" "unprognostic (3.20e-1)" "unprognostic (1.81e-1)" "unprognostic (2.75e-1)" "unprognostic (1.67e-1)" "unprognostic (2.36e-1)" "unprognostic (4.44e-2)" "unprognostic (2.01e-1)" "unprognostic (1.80e-2)" "unprognostic (3.18e-2)" "potential prognostic favorable (1.68e-5)" "potential prognostic unfavorable (1.84e-4)" "unprognostic (1.01e-1)" "unprognostic (7.05e-2)" "unprognostic (9.92e-2)" "unprognostic (3.17e-1)" "unprognostic (1.37e-3)" "unprognostic (3.78e-1)" "unprognostic (2.50e-1)" "unprognostic (3.81e-2)" "unprognostic (6.05e-2)" "unprognostic (3.50e-1)" "unprognostic (2.16e-2)" "unprognostic (1.11e-3)" "unprognostic (3.67e-2)" "unprognostic (2.09e-1)" "unprognostic (7.69e-3)" "unprognostic (1.15e-1)" "unprognostic (1.22e-1)" DDX52 ROK1 ENSG00000278053 "DExD-box helicase 52" Q9Y2R4 17 37609739-37643446 "Enzymes, Essential proteins, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 195.2;Endometrial glandular cells: 159.8;Late spermatids: 91.6;Renal collecting duct intercalated cells: 103.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056173 Uncertain Supported Nucleoplasm,Nucleoli NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 49: Non-specific - Transcription" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 51: Secretory epithelial cells - Mixed function" 14 "Nucleoplasm, Nucleoli" "HPA056173: " "unprognostic (3.15e-1)" "unprognostic (3.03e-2)" "unprognostic (1.07e-1)" "unprognostic (7.46e-2)" "unprognostic (5.97e-2)" "unprognostic (1.09e-1)" "unprognostic (6.48e-2)" "unprognostic (5.34e-1)" "unprognostic (6.38e-3)" "unprognostic (3.99e-3)" "unprognostic (2.58e-2)" "unprognostic (2.07e-1)" "potential prognostic unfavorable (8.27e-5)" "unprognostic (1.31e-2)" "unprognostic (2.49e-3)" "unprognostic (3.70e-1)" "unprognostic (3.41e-1)" "unprognostic (1.43e-2)" "unprognostic (2.21e-1)" "unprognostic (4.69e-2)" "unprognostic (2.61e-2)" "unprognostic (4.20e-2)" "unprognostic (2.90e-1)" "unprognostic (5.01e-2)" "unprognostic (2.37e-1)" "unprognostic (1.64e-1)" "unprognostic (5.22e-2)" "unprognostic (1.45e-1)" DDX53 "CAGE, CT26" ENSG00000184735 "DEAD-box helicase 53" Q86TM3 X 22999960-23003589 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 51 "testis: 5.0" "Group enriched" "Detected in some" 4 "Early spermatids: 60.5;Late primary spermatocytes: 43.7" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "Testicular Germ Cell Tumor (TCGA): 1.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 1.4;prostate cancer: 1.0" "Testis - Early spermatids, Testis - Late spermatids" HPA003186 Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 2: Neurons - Nucleosome" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 1 Nucleoplasm "Nucleoli, Cytosol" "HPA003186: " "unprognostic (2.00e-1)" DDX54 "APR-5, DP97, MGC2835" ENSG00000123064 "DEAD-box helicase 54" Q8TDD1 12 113157173-113185479 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028244, HPA070786" Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 36: Choroid plexus - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 38 "Nucleoplasm, Nucleoli, Golgi apparatus" "HPA028244: , HPA070786: " "unprognostic (2.29e-1)" "unprognostic (2.15e-2)" "unprognostic (2.36e-1)" "unprognostic (1.18e-1)" "unprognostic (4.53e-2)" "unprognostic (2.33e-2)" "unprognostic (2.33e-2)" "unprognostic (6.88e-2)" "potential prognostic unfavorable (8.49e-4)" "unprognostic (8.07e-3)" "potential prognostic favorable (5.60e-4)" "unprognostic (1.00e-1)" "unprognostic (1.76e-1)" "validated prognostic unfavorable (4.37e-4)" "validated prognostic unfavorable (2.92e-5)" "potential prognostic unfavorable (7.74e-4)" "unprognostic (1.67e-3)" "unprognostic (1.64e-1)" "unprognostic (1.84e-2)" "unprognostic (6.47e-2)" "unprognostic (2.55e-1)" "unprognostic (1.47e-2)" "unprognostic (6.12e-2)" "unprognostic (7.07e-2)" "unprognostic (9.19e-2)" "unprognostic (6.80e-3)" "unprognostic (1.22e-1)" "unprognostic (9.54e-2)" "unprognostic (5.20e-1)" "unprognostic (3.33e-1)" "unprognostic (4.63e-2)" DDX55 KIAA1595 ENSG00000111364 "DEAD-box helicase 55" Q8NHQ9 12 123602077-123620943 "Enzymes, Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Helicase, Hydrolase, RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 107.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039962, HPA044101" Approved Enhanced Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 15: Bone marrow - Innate immune response" "Cluster 6: Non-specific - Immune response" "Cluster 38: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 24 Nucleoli "Nucleoplasm, Cytosol" "HPA039962: , HPA044101: " "unprognostic (2.73e-2)" "unprognostic (2.18e-2)" "unprognostic (1.54e-1)" "unprognostic (5.15e-2)" "unprognostic (2.66e-1)" "unprognostic (2.60e-2)" "unprognostic (2.77e-1)" "unprognostic (4.51e-2)" "unprognostic (2.43e-1)" "potential prognostic unfavorable (5.16e-4)" "unprognostic (1.47e-3)" "unprognostic (7.23e-2)" "unprognostic (7.93e-2)" "potential prognostic unfavorable (3.85e-12)" "unprognostic (3.25e-2)" "unprognostic (1.12e-2)" "unprognostic (1.57e-2)" "unprognostic (1.20e-1)" "unprognostic (5.07e-2)" "unprognostic (4.89e-2)" "unprognostic (1.21e-1)" "unprognostic (1.34e-1)" "unprognostic (3.27e-3)" "potential prognostic unfavorable (4.49e-4)" "unprognostic (8.99e-2)" "unprognostic (3.02e-2)" "unprognostic (5.91e-2)" "unprognostic (4.33e-2)" "unprognostic (2.26e-1)" "unprognostic (1.20e-1)" "unprognostic (5.31e-2)" DDX56 NOH61 ENSG00000136271 "DEAD-box helicase 56" Q9NY93 7 44565804-44575051 "Enzymes, Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019749, CAB037320" Uncertain Supported "Nucleoli,Mitotic chromosome" Yes NA 100000 "Cluster 33: Non-specific - ATP binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 72 Nucleoli "Mitotic chromosome" "CAB037320: , HPA019749: " "unprognostic (3.56e-2)" "unprognostic (1.58e-2)" "unprognostic (4.69e-2)" "unprognostic (5.69e-2)" "unprognostic (4.41e-1)" "unprognostic (1.03e-1)" "unprognostic (7.73e-3)" "unprognostic (3.10e-2)" "unprognostic (3.26e-3)" "unprognostic (5.30e-2)" "unprognostic (1.24e-3)" "unprognostic (1.22e-1)" "unprognostic (8.11e-2)" "unprognostic (1.85e-3)" "potential prognostic unfavorable (8.17e-4)" "potential prognostic unfavorable (1.44e-4)" "unprognostic (6.09e-3)" "unprognostic (2.94e-1)" "unprognostic (8.58e-2)" "unprognostic (2.46e-1)" "unprognostic (3.67e-2)" "unprognostic (1.37e-1)" "unprognostic (5.99e-3)" "unprognostic (4.22e-3)" "unprognostic (2.81e-2)" "unprognostic (2.21e-1)" "unprognostic (4.30e-2)" "unprognostic (1.83e-1)" "unprognostic (2.47e-1)" "unprognostic (1.35e-2)" "unprognostic (1.92e-2)" DDX59 "DKFZP564B1023, ZNHIT5" ENSG00000118197 "DEAD-box helicase 59" Q5T1V6 1 200623896-200669907 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast myoepithelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047166 Approved Supported "Nucleoplasm,Vesicles,Actin filaments,Primary cilium,Primary cilium tip,Centrosome,Basal body" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 24: Neutrophils - Innate immunity signal integration" 1 "Nucleoplasm, Actin filaments" "Vesicles, Primary cilium, Primary cilium tip, Centrosome, Basal body" "HPA047166: " "unprognostic (9.45e-2)" "unprognostic (2.19e-1)" "unprognostic (4.23e-2)" "unprognostic (7.93e-2)" "unprognostic (2.75e-1)" "unprognostic (1.16e-1)" "unprognostic (1.19e-1)" "unprognostic (4.30e-3)" "unprognostic (1.63e-1)" "unprognostic (2.25e-2)" "unprognostic (3.30e-2)" "unprognostic (2.91e-1)" "unprognostic (9.13e-2)" "unprognostic (4.16e-2)" "unprognostic (5.02e-1)" "unprognostic (8.15e-2)" "unprognostic (2.10e-1)" "unprognostic (1.48e-1)" "unprognostic (8.56e-3)" "unprognostic (5.74e-2)" "unprognostic (2.94e-1)" "unprognostic (2.98e-1)" "unprognostic (1.97e-2)" "unprognostic (9.88e-2)" "unprognostic (5.91e-2)" "unprognostic (8.92e-2)" "unprognostic (9.01e-2)" "unprognostic (3.07e-1)" "unprognostic (1.57e-1)" "unprognostic (1.12e-1)" "unprognostic (1.75e-1)" DDX6 "HLR2, RCK, Rck/p54" ENSG00000110367 "DEAD-box helicase 6" P26196 11 118747763-118791164 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Cancer-related genes, Disease variant, Intellectual disability, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004668, HPA024201, HPA026644" Approved Supported "Plasma membrane,Midbody,Cytosol,Cytoplasmic bodies" Yes NA 25000 "Cluster 21: Neutrophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 307 "Cytoplasmic bodies" "Plasma membrane, Midbody, Cytosol" "CAB004668: , HPA024201: , HPA026644: " "unprognostic (4.70e-2)" "unprognostic (2.29e-3)" "unprognostic (4.46e-2)" "unprognostic (3.74e-3)" "unprognostic (7.85e-2)" "unprognostic (6.22e-2)" "unprognostic (2.09e-2)" "unprognostic (1.03e-1)" "unprognostic (3.91e-2)" "unprognostic (1.77e-2)" "potential prognostic favorable (1.10e-5)" "unprognostic (2.08e-3)" "unprognostic (4.46e-2)" "potential prognostic unfavorable (3.46e-4)" "unprognostic (2.37e-1)" "unprognostic (2.54e-1)" "unprognostic (1.09e-3)" "unprognostic (4.63e-2)" "unprognostic (2.78e-2)" "unprognostic (3.71e-2)" "potential prognostic unfavorable (1.27e-5)" "unprognostic (2.57e-2)" "unprognostic (6.79e-2)" "unprognostic (2.78e-1)" "unprognostic (8.54e-2)" "unprognostic (1.91e-2)" "unprognostic (4.54e-3)" "unprognostic (9.20e-2)" "unprognostic (1.64e-1)" "unprognostic (1.47e-1)" "unprognostic (1.47e-1)" DDX60 FLJ20035 ENSG00000137628 "DExD/H-box helicase 60" Q8IY21 4 168216291-168318883 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "stomach 1: 38.5" "Cell type enriched" "Detected in many" 4 "Foveolar cells: 404.9" "Cell type enhanced" "Detected in many" "endothelial cell: 118.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA046952 Approved Supported "Intermediate filaments,Centrosome,Cytosol" No No "Cluster 33: Non-specific - ATP binding" "Cluster 60: Stomach - Digestion" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 68: Foveolar cells - Mucosal defense" 3 Cytosol "Intermediate filaments, Centrosome" "HPA046952: " "unprognostic (1.45e-1)" "unprognostic (1.11e-1)" "unprognostic (1.48e-1)" "unprognostic (2.22e-1)" "unprognostic (1.40e-1)" "unprognostic (2.11e-1)" "unprognostic (8.18e-2)" "unprognostic (2.26e-2)" "unprognostic (6.69e-2)" "unprognostic (2.72e-2)" "potential prognostic favorable (8.87e-5)" "unprognostic (1.31e-3)" "unprognostic (2.23e-1)" "unprognostic (2.84e-2)" "potential prognostic favorable (9.42e-4)" "unprognostic (5.10e-3)" "unprognostic (1.31e-2)" "unprognostic (2.00e-1)" "unprognostic (2.37e-1)" "unprognostic (1.53e-1)" "unprognostic (7.08e-2)" "potential prognostic unfavorable (7.92e-5)" "unprognostic (1.34e-2)" "unprognostic (2.69e-1)" "unprognostic (1.57e-1)" "unprognostic (1.83e-2)" "unprognostic (2.76e-1)" "unprognostic (1.53e-1)" "unprognostic (8.14e-2)" "unprognostic (3.28e-2)" "unprognostic (6.38e-2)" DDX60L FLJ31033 ENSG00000181381 "DExD/H-box 60 like" Q5H9U9 4 168356735-168537786 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 48.4" "Group enriched" "Detected in many" 7 "Cardiomyocytes: 3361.1;Neutrophils: 1326.0" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 137.9;endothelial cell: 195.8;leukocyte: 116.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 33.0" "Group enriched" "Detected in all" 4 "granulocytes: 33.0;monocytes: 13.3" "Low cancer specificity" "Detected in many" "Spleen - Neutrophils_2, Stomach - Gastric mucous cells" "HPA043211, HPA055501" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 2 "Plasma membrane, Cytosol" "HPA043211: , HPA055501: " "unprognostic (8.40e-2)" "unprognostic (2.53e-1)" "unprognostic (3.19e-1)" "unprognostic (1.32e-2)" "unprognostic (1.93e-2)" "unprognostic (1.61e-1)" "unprognostic (4.25e-2)" "unprognostic (2.07e-1)" "unprognostic (2.66e-1)" "unprognostic (1.82e-2)" "unprognostic (1.41e-3)" "unprognostic (3.21e-1)" "unprognostic (9.76e-2)" "unprognostic (5.62e-2)" "unprognostic (4.73e-3)" "unprognostic (1.44e-3)" "unprognostic (2.88e-2)" "unprognostic (3.97e-2)" "unprognostic (1.27e-1)" "unprognostic (1.30e-1)" "unprognostic (8.02e-2)" "potential prognostic unfavorable (5.18e-5)" "unprognostic (2.24e-3)" "unprognostic (3.06e-1)" "unprognostic (6.74e-3)" "unprognostic (1.49e-3)" "unprognostic (7.02e-2)" "unprognostic (9.63e-2)" "unprognostic (2.38e-1)" "unprognostic (5.94e-2)" "unprognostic (3.64e-2)" DEAF1 "NUDR, SPN, ZMYND5" ENSG00000177030 "DEAF1 transcription factor" O75398 11 644233-707118 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 42.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 220.8;Esophageal apical cells: 342.2;Renal collecting duct intercalated cells: 90.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030302 Approved Supported "Nucleoplasm,Nucleoli fibrillar center" "Intracellular and membrane" "Developmental protein" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 84: Apical squamous epithelium - Cornification" 22 "Nucleoplasm, Nucleoli fibrillar center" "HPA030302: " "unprognostic (5.15e-2)" "unprognostic (2.23e-2)" "unprognostic (3.20e-1)" "unprognostic (2.52e-2)" "unprognostic (7.76e-2)" "unprognostic (2.42e-2)" "unprognostic (2.15e-2)" "unprognostic (1.03e-1)" "unprognostic (3.56e-2)" "unprognostic (3.06e-1)" "potential prognostic favorable (3.24e-5)" "unprognostic (1.38e-1)" "unprognostic (8.12e-2)" "potential prognostic unfavorable (5.71e-6)" "unprognostic (6.02e-2)" "unprognostic (2.15e-1)" "unprognostic (5.18e-2)" "unprognostic (3.78e-2)" "unprognostic (2.50e-1)" "unprognostic (5.70e-2)" "unprognostic (2.80e-1)" "unprognostic (2.04e-2)" "unprognostic (1.00e-1)" "unprognostic (2.19e-1)" "unprognostic (1.82e-2)" "unprognostic (4.27e-2)" "unprognostic (3.12e-1)" "unprognostic (2.45e-1)" "unprognostic (5.83e-2)" "unprognostic (2.16e-1)" "unprognostic (1.09e-1)" DECR1 "DECR, SDR18C1" ENSG00000104325 "2,4-dienoyl-CoA reductase 1" Q16698 8 90001405-90053633 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 70.1" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 432.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023160, HPA023162, HPA023238" Enhanced Supported Mitochondria,Cytosol No No 260000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 76: Non-specific - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" 9 Mitochondria Cytosol "HPA023160: , HPA023162: , HPA023238: " "unprognostic (8.48e-2)" "unprognostic (1.56e-2)" "unprognostic (5.61e-2)" "potential prognostic favorable (3.29e-4)" "unprognostic (1.32e-1)" "unprognostic (8.76e-2)" "unprognostic (7.41e-2)" "unprognostic (9.69e-3)" "unprognostic (8.38e-3)" "unprognostic (9.91e-3)" "potential prognostic favorable (9.96e-5)" "unprognostic (5.60e-2)" "unprognostic (2.45e-1)" "unprognostic (1.93e-3)" "unprognostic (4.39e-3)" "unprognostic (7.78e-2)" "unprognostic (2.99e-1)" "unprognostic (3.11e-1)" "unprognostic (1.54e-1)" "unprognostic (6.04e-2)" "unprognostic (1.18e-2)" "unprognostic (7.19e-2)" "unprognostic (1.73e-1)" "unprognostic (4.85e-2)" "unprognostic (3.48e-3)" "unprognostic (3.38e-3)" "unprognostic (6.00e-2)" "unprognostic (1.17e-1)" "unprognostic (1.51e-1)" "unprognostic (1.49e-1)" "unprognostic (1.45e-1)" DECR2 "PDCR, SDR17C1" ENSG00000242612 "2,4-dienoyl-CoA reductase 2" Q9NUI1 16 401858-412487 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 174.4" "Cell type enhanced" "Detected in some" "Astrocytes: 6.7;Bergmann glia: 6.3;Brain excitatory neurons: 3.8;Brain inhibitory neurons: 3.5;Distal convoluted tubule cells: 4.0;Ependymal cells: 4.5;Loop of henle epithelial cells: 5.2;Oligodendrocyte progenitor cells: 4.1;Papillary tip epithelial cells: 4.0;Proximal tubule cells: 24.9;Renal collecting duct intercalated cells: 4.6;Renal collecting duct principal cells: 4.2;Renal connecting tubule cells: 4.4;Tuft cells: 11.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047631 Approved Peroxisomes,Microtubules NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 70: Non-specific - Protein processing" "Cluster 14: Neurons - Synaptic function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 88: Proximal tubular cells - Transmembrane transport" 8 Peroxisomes Microtubules "HPA047631: " "unprognostic (4.04e-2)" "unprognostic (5.15e-2)" "unprognostic (2.71e-1)" "unprognostic (3.99e-1)" "unprognostic (6.47e-2)" "unprognostic (4.50e-2)" "unprognostic (1.19e-1)" "unprognostic (2.92e-1)" "unprognostic (1.48e-1)" "unprognostic (1.92e-1)" "unprognostic (2.84e-3)" "unprognostic (1.62e-1)" "unprognostic (6.97e-3)" "unprognostic (2.28e-2)" "unprognostic (1.70e-3)" "unprognostic (8.16e-2)" "unprognostic (2.43e-2)" "unprognostic (1.71e-1)" "unprognostic (2.39e-1)" "unprognostic (9.95e-2)" "unprognostic (2.58e-1)" "unprognostic (5.05e-2)" "unprognostic (3.81e-2)" "unprognostic (2.19e-1)" "unprognostic (9.43e-2)" "unprognostic (1.32e-1)" "unprognostic (7.93e-2)" "unprognostic (7.77e-2)" "unprognostic (2.12e-1)" "unprognostic (2.14e-1)" "unprognostic (1.13e-2)" DEDD "CASP8IP1, DEDD1, DEFT, FLDED1, KE05" ENSG00000158796 "Death effector domain containing" O75618 1 161120974-161132688 "Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 142.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064486, HPA065101, HPA073628" Approved Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 24: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 45: Non-specific - Nuclear processes" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 8 "Nucleoplasm, Nucleoli" Cytosol "HPA064486: , HPA065101: , HPA073628: " "unprognostic (2.17e-1)" "unprognostic (2.30e-1)" "unprognostic (3.13e-1)" "unprognostic (1.21e-1)" "unprognostic (1.54e-1)" "unprognostic (5.09e-1)" "unprognostic (8.83e-2)" "unprognostic (2.06e-3)" "unprognostic (1.99e-1)" "unprognostic (1.61e-3)" "potential prognostic favorable (1.59e-5)" "unprognostic (3.93e-2)" "unprognostic (1.05e-1)" "unprognostic (2.99e-3)" "unprognostic (1.27e-1)" "unprognostic (2.75e-2)" "potential prognostic unfavorable (3.46e-5)" "unprognostic (1.37e-1)" "unprognostic (4.58e-2)" "unprognostic (3.21e-1)" "unprognostic (1.51e-2)" "unprognostic (2.72e-2)" "unprognostic (1.75e-1)" "unprognostic (1.07e-2)" "unprognostic (6.69e-2)" "unprognostic (1.04e-1)" "unprognostic (5.17e-2)" "unprognostic (4.71e-2)" "unprognostic (1.80e-1)" "unprognostic (2.21e-3)" "unprognostic (4.79e-2)" DEDD2 FLAME-3 ENSG00000160570 "Death effector domain containing 2" Q8WXF8 19 42198598-42220140 "Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 110.9;Neutrophils: 173.9;Syncytiotrophoblasts: 211.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043419 Approved Nucleoplasm NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 64: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 4: Non-specific - Transcription" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 6 Nucleoplasm "HPA043419: " "unprognostic (2.68e-1)" "unprognostic (6.39e-2)" "unprognostic (1.56e-1)" "unprognostic (5.40e-2)" "unprognostic (1.89e-1)" "unprognostic (2.20e-2)" "unprognostic (2.74e-2)" "potential prognostic unfavorable (1.02e-4)" "unprognostic (6.93e-2)" "unprognostic (4.38e-3)" "potential prognostic favorable (6.86e-5)" "unprognostic (2.93e-2)" "unprognostic (7.85e-2)" "unprognostic (8.74e-2)" "unprognostic (3.22e-2)" "unprognostic (6.59e-3)" "unprognostic (8.35e-2)" "unprognostic (2.28e-2)" "unprognostic (1.63e-1)" "unprognostic (2.49e-1)" "unprognostic (2.23e-1)" "unprognostic (6.17e-2)" "unprognostic (2.06e-1)" "unprognostic (3.08e-2)" "unprognostic (2.41e-2)" "unprognostic (1.90e-1)" "unprognostic (1.23e-1)" "unprognostic (2.04e-1)" "unprognostic (1.63e-1)" "unprognostic (1.27e-2)" "unprognostic (1.22e-1)" DEF6 "IBP, SLAT, SWAP70L" ENSG00000023892 "DEF6 guanine nucleotide exchange factor" Q9H4E7 6 35297818-35321771 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 60.1" "Cell type enhanced" "Detected in many" "Hofbauer cells: 197.0;Late primary spermatocytes: 97.2;Late spermatids: 252.5;Microglia: 92.7;Neutrophil progenitors: 104.2;Neutrophils: 114.5;NK-cells: 91.7;T-cells: 84.4" "Group enriched" "Detected in many" 7 "central nervous system macrophage: 110.8;leukocyte: 99.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 58.2;Myeloma: 41.2" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Skin - Keratinocyte (other), Spleen - T-cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA038975, HPA038976" Enhanced Enhanced Nucleoplasm Yes NA "Cluster 33: Non-specific - ATP binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 20 Nucleoplasm "HPA038975: , HPA038976: " "unprognostic (1.78e-1)" "validated prognostic favorable (1.16e-4)" "validated prognostic favorable (2.15e-4)" "unprognostic (6.06e-3)" "unprognostic (7.50e-2)" "unprognostic (1.77e-1)" "unprognostic (9.15e-2)" "unprognostic (1.20e-1)" "unprognostic (2.62e-2)" "unprognostic (2.19e-2)" "unprognostic (5.05e-3)" "unprognostic (1.64e-1)" "unprognostic (3.56e-1)" "unprognostic (2.54e-1)" "unprognostic (1.14e-2)" "unprognostic (8.68e-3)" "unprognostic (4.23e-2)" "unprognostic (2.08e-1)" "unprognostic (8.34e-2)" "unprognostic (6.27e-2)" "unprognostic (6.38e-3)" "unprognostic (1.07e-1)" "unprognostic (2.45e-2)" "unprognostic (2.99e-3)" "unprognostic (1.69e-1)" "unprognostic (7.12e-2)" "unprognostic (1.84e-1)" "unprognostic (6.65e-2)" "unprognostic (4.42e-2)" "unprognostic (3.53e-2)" "unprognostic (1.14e-1)" DEF8 FLJ20186 ENSG00000140995 "Differentially expressed in FDCP 8 homolog" Q6ZN54 16 89948697-89968060 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 200.0;Esophageal suprabasal cells: 96.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041745, HPA049434" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 64: Non-specific - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 2 "Nucleoplasm, Cytosol" "HPA041745: , HPA049434: " "unprognostic (5.95e-3)" "unprognostic (1.54e-2)" "unprognostic (2.68e-1)" "unprognostic (1.09e-1)" "unprognostic (4.51e-2)" "unprognostic (3.21e-2)" "unprognostic (9.02e-2)" "potential prognostic favorable (5.24e-5)" "unprognostic (1.27e-1)" "unprognostic (2.79e-2)" "unprognostic (8.52e-3)" "unprognostic (1.98e-1)" "unprognostic (9.28e-3)" "unprognostic (1.50e-2)" "unprognostic (1.58e-1)" "unprognostic (4.24e-2)" "unprognostic (1.33e-2)" "unprognostic (7.49e-2)" "unprognostic (3.94e-1)" "unprognostic (2.19e-2)" "unprognostic (1.71e-1)" "unprognostic (9.61e-3)" "unprognostic (1.65e-3)" "unprognostic (9.50e-3)" "unprognostic (2.39e-1)" "unprognostic (1.42e-1)" "unprognostic (3.58e-1)" "unprognostic (2.11e-2)" "unprognostic (1.18e-1)" "unprognostic (4.22e-3)" "unprognostic (9.28e-2)" DEFA1 "DEF1, DEFA2, HNP-1, MRS" ENSG00000206047 "Defensin alpha 1" P59665 8 6977649-6980092 "Cancer-related genes, Plasma proteins, Predicted secreted proteins, Transporters" "Antiviral defense, Host-virus interaction" "Antibiotic, Antimicrobial, Defensin, Fungicide" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 275 "bone marrow: 59493.5" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 1.5;Kidney Renal Clear Cell Carcinoma (TCGA): 1.7" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 21 "neutrophil: 2665.7" "Lineage enriched" "Detected in many" 21 "granulocytes: 2665.7" "Cancer enriched" "Detected in single" 60 "Leukemia: 47.0" "Lung - Neutrophils_1, Spleen - Neutrophils_1" "CAB032548, HPA052517" Enhanced "Secreted to blood" Defense NA NA 113000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 4 "CAB032548: , HPA052517: " "unprognostic (5.00e-3)" "unprognostic (1.65e-1)" "unprognostic (1.38e-2)" DEFA1B ENSG00000240247 "Defensin alpha 1B" P59665 8 6996766-6999198 "Cancer-related genes, Plasma proteins, Predicted secreted proteins, Transporters" "Antiviral defense, Host-virus interaction" "Antibiotic, Antimicrobial, Defensin, Fungicide" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 13 "lung: 563.0;lymphoid tissue: 1718.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Glioblastoma Multiforme (TCGA): 2.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Neutrophils_1, Spleen - Neutrophils_1" HPA052517 Supported "Secreted to blood" Defense NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 5: Spleen - Immune response" "Cluster 72: Neuronal - Signal transduction" 4 "HPA052517: " "unprognostic (7.50e-1)" DEFA3 "DEF3, HNP-3" ENSG00000239839 "Defensin alpha 3" P59666 8 7015869-7018297 "Cancer-related genes, Predicted secreted proteins" "Antiviral defense" "Antibiotic, Antimicrobial, Defensin, Fungicide" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 59 "bone marrow: 34745.3" "Cell type enriched" "Detected in some" 219 "Neutrophil progenitors: 5810.9" "Group enriched" "Detected in some" 5 "Glioblastoma Multiforme (TCGA): 3.4;Kidney Renal Clear Cell Carcinoma (TCGA): 1.1" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 20 "neutrophil: 833.8" "Lineage enriched" "Detected in many" 20 "granulocytes: 833.8" "Cancer enriched" "Detected in single" 223 "Leukemia: 22.3" "Lung - Neutrophils_1, Pituitary gland - Neutrophils, Spleen - Neutrophils_1" HPA052517 Supported "Secreted to blood" Defense NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" "HPA052517: " "unprognostic (1.03e-1)" "unprognostic (1.77e-2)" DEFA4 "DEF4, HP-4" ENSG00000164821 "Defensin alpha 4" P12838 8 6935820-6938306 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin, Fungicide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 54 "bone marrow: 2547.5" "Cell type enriched" "Detected in some" 21 "Neutrophil progenitors: 392.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 13 "neutrophil: 13.2" "Lineage enriched" "Detected in many" 13 "granulocytes: 13.2" "Cancer enriched" "Detected in single" 291 "Leukemia: 29.1" "Lung - Neutrophils_1, Pituitary gland - Neutrophils, Spleen - Neutrophils_1" HPA051266 Enhanced "Secreted to blood" Defense NA NA 23000 "Cluster 21: Neutrophils - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" "HPA051266: " DEFA5 "DEF5, HD-5" ENSG00000164816 "Defensin alpha 5" Q01523 8 7055304-7056739 "Plasma proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Antibiotic, Antimicrobial, Defensin, Fungicide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 754 "intestine: 9025.0" "Cell type enriched" "Detected in some" 760 "Paneth cells: 84212.6" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 216.0;Colon Adenocarcinoma (TCGA): 216.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 29 "Gastric cancer: 121.3" "HPA015309, HPA015775, CAB069919" Enhanced Approved Vesicles,Midbody "Secreted to digestive system" Immunity Yes NA 240000 "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 32: Non-specific - Cell proliferation" "Cluster 15: Non-specific - Protein processing" 1 Vesicles Midbody "CAB069919: , HPA015309: , HPA015775: " "unprognostic (3.14e-2)" "unprognostic (6.41e-2)" "unprognostic (2.40e-1)" "unprognostic (2.60e-1)" "unprognostic (7.09e-3)" "unprognostic (6.37e-3)" "unprognostic (9.21e-2)" DEFA6 "DEF6, HD-6" ENSG00000164822 "Defensin alpha 6" Q01524 8 6924697-6926076 "Plasma proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Antibiotic, Antimicrobial, Defensin, Fungicide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 861 "intestine: 4530.5" "Cell type enriched" "Detected in some" 1132 "Paneth cells: 45828.7" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 25.5;Colon Adenocarcinoma (TCGA): 100.9;Rectum Adenocarcinoma (TCGA): 70.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "colorectal cancer: 5.7;Gastric cancer: 12.8" HPA019462 Enhanced "Secreted to digestive system" Immunity NA NA 41000 "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 15: Non-specific - Protein processing" 3 "HPA019462: " "unprognostic (2.44e-2)" "unprognostic (2.93e-1)" "unprognostic (1.66e-1)" "unprognostic (3.56e-1)" "unprognostic (1.14e-1)" "unprognostic (4.05e-3)" "unprognostic (2.09e-1)" DEFB1 "BD1, DEFB-1, DEFB101, HBD-1, HBD1, MGC51822" ENSG00000164825 "Defensin beta 1" P60022 8 6870592-6877936 "Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "kidney: 2702.4;pancreas: 1076.1;salivary gland: 2947.6" "Cell type enhanced" "Detected in many" "Cholangiocytes: 1195.2;Distal convoluted tubule cells: 488.5;Endometrial glandular cells: 799.6;Endometrial luminal cells: 482.5;Endometrial secretory cells: 447.9;Epididymal clear cells: 1284.0;Renal connecting tubule cells: 475.3;Salivary acinar cells: 1021.5;Salivary basal cells: 1425.1;Salivary duct cells: 1189.9;Salivary ionocytes: 2730.1;Salivary myoepithelial cells: 509.4" "Group enriched" "Detected in some" 6 "fibroblast: 2.5;midbrain-derived inhibitory: 4.9;thalamic excitatory: 5.9" "Group enriched" "Detected in many" 6 "Kidney Chromophobe (TCGA): 2427.5;Kidney Renal Papillary Cell Carcinoma (TCGA): 690.1" "Group enriched" "Detected in many" 5 "amygdala: 2.9;cerebellum: 3.4;hypothalamus: 1.8;midbrain: 4.7;thalamus: 6.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Leukemia: 57.7;ovarian cancer: 43.5" "Kidney - Intercalated cells, Minor Salivary Gland - Minor salivary glandular cells" "Not detected" "Not detected" "Secreted in other tissues" Defense NA NA 620000 "Cluster 72: Kidney - Transmembrane transport" "Cluster 38: Sub-cortical - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 38: Secretory epithelial cells - Exocrine secretion" "unprognostic (2.66e-1)" "unprognostic (2.97e-1)" "unprognostic (4.11e-2)" "unprognostic (2.64e-1)" "unprognostic (2.28e-2)" "unprognostic (2.28e-1)" "unprognostic (5.92e-2)" "unprognostic (7.70e-2)" "unprognostic (1.19e-1)" "unprognostic (4.25e-2)" "unprognostic (1.21e-2)" "unprognostic (3.31e-1)" "unprognostic (1.06e-3)" "potential prognostic unfavorable (4.03e-4)" "unprognostic (1.05e-1)" "unprognostic (5.52e-2)" "unprognostic (2.03e-2)" "unprognostic (2.77e-2)" "unprognostic (4.58e-1)" "unprognostic (4.05e-3)" "unprognostic (2.14e-1)" "unprognostic (3.57e-2)" "unprognostic (1.07e-1)" "potential prognostic favorable (7.27e-4)" "unprognostic (1.69e-1)" "unprognostic (1.92e-1)" "unprognostic (1.88e-1)" "unprognostic (3.09e-2)" "unprognostic (1.27e-1)" DEFB103A "DEFB-3, DEFB103, DEFB3, HBD-3, HBD3, HBP-3, HBP3" ENSG00000176797 "Defensin beta 103A" P81534 8 7881392-7882663 "Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 4.7;esophagus: 6.3;lymphoid tissue: 7.1;salivary gland: 7.6;vagina: 9.5" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 9 "Head and Neck Squamous Cell Carcinoma (TCGA): 105.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 2.0" "Secreted in other tissues" Defense NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" 9 "unprognostic (2.78e-1)" "unprognostic (3.14e-2)" "unprognostic (8.86e-2)" "unprognostic (6.33e-2)" "unprognostic (2.92e-1)" "unprognostic (1.88e-1)" DEFB103B ENSG00000177243 "Defensin beta 103B" P81534 8 7428888-7430348 "Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "Head and Neck Squamous Cell Carcinoma (TCGA): 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" Defense NA NA "Cluster 53: Squamous epithelial cells - Keratinization" 9 "unprognostic (2.32e-2)" DEFB104A "DEFB-4, DEFB104, DEFB4" ENSG00000176782 "Defensin beta 104A" Q8WTQ1 8 7836436-7841242 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 755 "epididymis: 1228.6" "Cell type enriched" "Detected in single" 17 "Epididymal principal cells: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045292 Supported "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 15: Kidney cancer - Membrane components" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" "HPA045292: " DEFB104B ENSG00000177023 "Defensin beta 104B" Q8WTQ1 8 7470308-7475082 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045292 Supported "Secreted in male reproductive system" Defense NA NA "HPA045292: " DEFB105A "DEFB-5, DEFB105" ENSG00000186562 "Defensin beta 105A" Q8NG35 8 7821004-7823880 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1993 "epididymis: 1166.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.9" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Secreted in male reproductive system" Defense NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 48: Non-specific - Mixed function" "Cluster 56: Non-specific - Sensory perception" DEFB105B ENSG00000186599 "Defensin beta 105B" Q8NG35 8 7487679-7489593 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 2379 "epididymis: 473.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 46: Lymphoma - Humoral immune response" DEFB106A "DEFB-6, DEFB106" ENSG00000186579 "Defensin beta 106A" Q8N104 8 7825139-7829053 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 17254 "epididymis: 2870.7" "Cell type enriched" "Detected in single" 64 "Epididymal principal cells: 6.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045592 Supported "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 15: Kidney cancer - Membrane components" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" "HPA045592: " DEFB106B ENSG00000187082 "Defensin beta 106B" Q8N104 8 7482504-7486400 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 377 "epididymis: 37.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045592 Supported "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" "HPA045592: " DEFB107A "DEFB-7, DEFB107" ENSG00000186572 "Defensin beta 107A" Q8IZN7 8 7811720-7815716 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 1319 "epididymis: 131.9" "Cell type enriched" "Detected in single" 13 "Epididymal principal cells: 3.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045626 Approved "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" "HPA045626: " DEFB107B HsT21816 ENSG00000198129 "Defensin beta 107B" Q8IZN7 8 7495911-7509311 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 5014 "epididymis: 501.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045626 Approved "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 15: Kidney cancer - Membrane components" "HPA045626: " DEFB108B ENSG00000184276 "Defensin beta 108B" Q8NET1 11 71833200-71837710 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 121 "epididymis: 12.1" "Cell type enriched" "Detected in some" 27 "Epididymal principal cells: 63.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 3 DEFB109B DEFB109P1B ENSG00000206034 "Defensin beta 109B" Q30KR1 8 7312722-7320096 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 8 "epididymis: 14.9" "Cell type enhanced" "Detected in some" "Bergmann glia: 1.9;Brain excitatory neurons: 1.1;Cardiomyocytes: 3.0;Epicardial cells: 6.8;Myosatellite cells: 1.0;Oligodendrocyte progenitor cells: 1.3;Oligodendrocytes: 2.6;Retinal amacrine cells: 1.4" "Low cell type specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Secreted in male reproductive system" Defense NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 27: Breast cancer - Unknown function" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" DEFB110 "DEFB-10, DEFB-11, DEFB111" ENSG00000203970 "Defensin beta 110" Q30KQ9 6 50009138-50021994 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 4672 "epididymis: 820.7" "Cell type enriched" "Detected in some" 48 "Epididymal principal cells: 495.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" DEFB112 DEFB-12 ENSG00000180872 "Defensin beta 112" 6 50042099-50049929 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 56 "epididymis: 23.2" "Cell type enriched" "Detected in some" 52 "Epididymal principal cells: 107.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" DEFB113 DEFB-13 ENSG00000214642 "Defensin beta 113" Q30KQ7 6 49968677-49969625 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 447 "epididymis: 44.6" "Cell type enriched" "Detected in single" 206 "Epididymal principal cells: 20.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" DEFB114 DEFB-14 ENSG00000177684 "Defensin beta 114" Q30KQ6 6 49960249-49964164 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 498 "epididymis: 49.7" "Cell type enriched" "Detected in single" 116 "Epididymal principal cells: 71.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" DEFB115 DEFB-15 ENSG00000215547 "Defensin beta 115" Q30KQ5 20 31257664-31259632 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 11 "epididymis: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA053160 Uncertain "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 7: Liver cancer - Metabolism" 2 "HPA053160: " DEFB116 DEFB-16 ENSG00000215545 "Defensin beta 116" Q30KQ4 20 31303212-31308585 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047430 Uncertain "Secreted in male reproductive system" Defense NA NA "Cluster 51: Myeloma - Immunoglobulins" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" "HPA047430: " DEFB118 "C20orf63, DEFB-18, dJ1018D12.3, ESC42" ENSG00000131068 "Defensin beta 118" Q96PH6 20 31368601-31373923 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 9358 "epididymis: 935.8" "Cell type enriched" "Detected in some" 127 "Epididymal principal cells: 3732.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA042634 Enhanced "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 2 "HPA042634: " DEFB119 "DEFB-19, DEFB-20, DEFB120" ENSG00000180483 "Defensin beta 119" Q8N690 20 31377164-31390590 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "epididymis: 1809.3" "Cell type enriched" "Detected in some" 5 "Epididymal principal cells: 2819.2" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 87 "Testicular Germ Cell Tumor (TCGA): 8.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Sertoli cells" "Not detected" "Not detected" "Region enriched" "Detected in single" 8 "spinal cord: 1.9" HPA043059 Supported Approved Mitochondria "Secreted in male reproductive system" Defense NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" Mitochondria "HPA043059: " "unprognostic (8.99e-1)" "unprognostic (2.38e-1)" DEFB121 DEFB-21 ENSG00000204548 "Defensin beta 121" Q5J5C9 20 31404845-31412838 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 12056 "epididymis: 2453.5" "Cell type enriched" "Detected in some" 89 "Epididymal principal cells: 2744.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" HPA079460 Enhanced "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 8 "HPA079460: " DEFB123 DEFB-23 ENSG00000180424 "Defensin beta 123" Q8N688 20 31440632-31450257 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 458 "epididymis: 149.9;testis: 206.5" "Group enriched" "Detected in some" 6 "Epididymal principal cells: 118.6;Late spermatids: 59.7;Sertoli cells: 229.5" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 14 "Testicular Germ Cell Tumor (TCGA): 7.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Sertoli cells" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" Defense NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" "unprognostic (1.07e-1)" DEFB124 DEFB-24 ENSG00000180383 "Defensin beta 124" Q8NES8 20 31465471-31476757 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "testis: 1.0" "Cell type enhanced" "Detected in some" "Decidual stromal cells: 12.4;Endometrial stromal cells: 10.6;Epicardial cells: 4.5;Epididymal principal cells: 5.7;Fallopian tube ciliated cells: 16.8;Pericytes: 15.9;Respiratory ciliated cells: 8.0;Vascular smooth muscle cells: 3.1" "Cell type enhanced" "Detected in some" "pericyte: 2.6;vascular associated smooth muscle cell: 1.8" "Cancer enriched" "Detected in some" 7 "Testicular Germ Cell Tumor (TCGA): 9.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Enteric glia cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted in other tissues" Defense NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 3 "unprognostic (8.56e-1)" "unprognostic (1.74e-1)" "unprognostic (1.81e-1)" DEFB125 DEFB-25 ENSG00000178591 "Defensin beta 125" Q8N687 20 87250-97094 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 13 "epididymis: 1.4;seminal vesicle: 1.1" "Group enriched" "Detected in some" 4 "Adipocytes: 4.2;Cardiomyocytes: 6.8;Epicardial cells: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" Defense NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" DEFB126 "bA530N10.1, C20orf8, DEFB-26" ENSG00000125788 "Defensin beta 126" Q9BYW3 20 142590-145751 "Disease related genes, Predicted secreted proteins" Fertilization "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 297 "epididymis: 1210.1" "Cell type enriched" "Detected in some" 46 "Epididymal principal cells: 820.8" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Ovary Serous Cystadenocarcinoma (TCGA): 2.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" "unprognostic (1.38e-1)" "unprognostic (1.37e-2)" "unprognostic (2.28e-1)" "unprognostic (2.31e-1)" "unprognostic (4.89e-1)" DEFB127 "bA530N10.2, C20orf73, DEF-27" ENSG00000088782 "Defensin beta 127" Q9H1M4 20 157454-159163 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1161 "epididymis: 1016.3" "Cell type enriched" "Detected in some" 66 "Epididymal principal cells: 1189.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 12 DEFB128 DEFB-28 ENSG00000185982 "Defensin beta 128" Q7Z7B8 20 187853-189711 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 11250 "epididymis: 1124.9" "Cell type enriched" "Detected in some" 303 "Epididymal principal cells: 468.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 1 DEFB129 "bA530N10.3, C20orf87, DEFB-29" ENSG00000125903 "Defensin beta 129" Q9H1M3 20 227258-229886 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 584 "epididymis: 1833.2" "Cell type enriched" "Detected in some" 84 "Epididymal principal cells: 864.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA014581 Enhanced "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 34: Testis cancer - Unknown function" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" 2 "HPA014581: " DEFB130A "DEFB-30, DEFB130, DEFB30" ENSG00000232948 "Defensin beta 130A" P0DP74 8 12310962-12318316 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 24 "epididymis: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 37: Neurons - Mixed function" "Cluster 56: Non-specific - Sensory perception" DEFB130B ENSG00000233050 "Defensin beta 130B" P0DP73 8 12064389-12071747 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 24 "epididymis: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 37: Neurons - Mixed function" "Cluster 56: Non-specific - Sensory perception" DEFB131A "DEFB-31, DEFB131" ENSG00000186146 "Defensin beta 131A" P59861 4 9444414-9450666 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "epididymis: 125.9" "Cell type enriched" "Detected in some" 32 "Epididymal principal cells: 385.1" "Cell type enhanced" "Detected in single" "lower rhombic lip: 2.4" "Cancer enriched" "Detected in single" 28 "Thyroid Carcinoma (TCGA): 4.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Secreted in other tissues" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 49: Hindbrain - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" 1 "unprognostic (1.82e-1)" DEFB131B ENSG00000225805 "Defensin beta 131B" A0A096LNP1 11 71878453-71884561 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 67 "epididymis: 57.2" "Cell type enhanced" "Detected in some" "Adipocytes: 6.3;Cardiomyocytes: 4.5;Epicardial cells: 11.4;Epididymal principal cells: 39.7;Fibro-adipogenic progenitors: 3.9;Retinal ganglion cells: 7.7" "Cell type enhanced" "Detected in some" "vascular associated smooth muscle cell: 2.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" "unprognostic (2.33e-1)" "unprognostic (2.54e-2)" "potential prognostic favorable (4.97e-4)" "unprognostic (2.58e-2)" "unprognostic (3.36e-1)" "unprognostic (5.39e-2)" "unprognostic (6.32e-2)" "unprognostic (1.06e-1)" DEFB132 "DEFB32, RP5-1103G7.6" ENSG00000186458 "Defensin beta 132" Q7Z7B7 20 257724-261096 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "epididymis: 256.0" "Cell type enriched" "Detected in some" 65 "Epididymal principal cells: 665.9" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Liver Hepatocellular Carcinoma (TCGA): 1.0;Prostate Adenocarcinoma (TCGA): 2.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 63 "prostate cancer: 6.3" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Prostate - Prostate glandular cells" HPA046399 Approved "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 60: Prostate cancer - Unknown function" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" 1 "HPA046399: " "unprognostic (1.80e-2)" "potential prognostic favorable (4.21e-4)" "unprognostic (2.39e-2)" DEFB134 ENSG00000205882 "Defensin beta 134" Q4QY38 8 11993174-12000752 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 12 "epididymis: 23.7" "Group enriched" "Detected in some" 9 "Early spermatids: 2.7;Epididymal principal cells: 4.7;Late spermatids: 4.8" "Cell type enhanced" "Detected in single" "mammillary body: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Secreted in male reproductive system" Defense NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" DEFB135 ENSG00000205883 "Defensin beta 135" Q30KP9 8 11982256-11984590 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 353 "epididymis: 53.4" "Cell type enriched" "Detected in single" 107 "Epididymal principal cells: 22.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "white matter: 1.5" "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" DEFB136 DEFB137 ENSG00000205884 "Defensin beta 136" Q30KP8 8 11973937-11974599 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin, Fungicide" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 7 "epididymis: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA068255 Enhanced "Secreted in male reproductive system" Defense NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" "HPA068255: " DEFB4A "DEFB-2, DEFB102, DEFB2, DEFB4, HBD-2, SAP1" ENSG00000171711 "Defensin beta 4A" O15263 8 7894677-7896716 "Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 72.0;esophagus: 150.9" "Group enriched" "Detected in some" 4 "Esophageal apical cells: 146.8;Foveolar cells: 67.9" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Head and Neck Squamous Cell Carcinoma (TCGA): 154.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "head and neck cancer: 3.7;Uterine cancer: 8.1" "Secreted in other tissues" Defense NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 2 "unprognostic (2.27e-1)" "unprognostic (9.88e-3)" "unprognostic (3.80e-2)" "unprognostic (2.07e-1)" "unprognostic (1.73e-1)" "unprognostic (3.42e-1)" "unprognostic (2.51e-1)" "unprognostic (4.67e-2)" "unprognostic (3.18e-1)" "unprognostic (4.46e-1)" "unprognostic (4.57e-2)" "unprognostic (4.19e-1)" DEFB4B DEFB4P ENSG00000177257 "Defensin beta 4B" O15263 8 7414855-7416863 "Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 9.6;lymphoid tissue: 3.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 1.5;Endometrial secretory cells: 7.8;Esophageal apical cells: 8.5;Foveolar cells: 1.2;Respiratory deuterosomal cells: 2.1;Transitional alveolar cells: 2.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Head and Neck Squamous Cell Carcinoma (TCGA): 15.3;Skin Cutaneous Melanoma (TCGA): 6.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "head and neck cancer: 1.3" "Secreted in other tissues" Defense NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 84: Apical squamous epithelium - Cornification" 1 "unprognostic (1.34e-1)" "unprognostic (1.21e-1)" "unprognostic (3.17e-1)" DEGS1 "DEGS-1, Des-1, DES1, FADS7, MLD" ENSG00000143753 "Delta 4-desaturase, sphingolipid 1" O15121 1 224175756-224193441 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Isomerase, Oxidoreductase" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "skin 1: 505.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 244.1;Cytotrophoblasts: 361.6;Endometrial glandular cells: 226.6;Suprabasal keratinocytes: 239.6;Syncytiotrophoblasts: 237.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076422 Supported "Plasma membrane,Cytokinetic bridge,Primary cilium,Mitochondria" Yes NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 37: Skin - Keratinization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 45: Non-specific - Nuclear processes" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 7 Mitochondria "Plasma membrane, Cytokinetic bridge, Primary cilium" "HPA076422: " "unprognostic (2.90e-1)" "unprognostic (2.76e-1)" "unprognostic (2.69e-1)" "unprognostic (5.14e-2)" "unprognostic (1.48e-1)" "unprognostic (7.63e-3)" "unprognostic (2.81e-2)" "potential prognostic unfavorable (9.71e-5)" "unprognostic (7.72e-2)" "unprognostic (6.13e-3)" "unprognostic (1.30e-1)" "unprognostic (7.79e-2)" "unprognostic (1.49e-3)" "potential prognostic unfavorable (2.75e-5)" "unprognostic (1.17e-2)" "unprognostic (4.17e-3)" "unprognostic (1.98e-3)" "unprognostic (3.14e-2)" "unprognostic (8.32e-2)" "unprognostic (7.89e-2)" "potential prognostic unfavorable (4.99e-4)" "unprognostic (1.28e-1)" "unprognostic (2.24e-1)" "unprognostic (3.33e-1)" "unprognostic (4.83e-3)" "unprognostic (3.26e-1)" "unprognostic (2.31e-1)" "unprognostic (3.40e-2)" "unprognostic (5.44e-2)" "unprognostic (9.94e-2)" "unprognostic (1.81e-3)" DEGS2 "C14orf66, DES2, FADS8" ENSG00000168350 "Delta 4-desaturase, sphingolipid 2" Q6QHC5 14 100143957-100159645 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 36.8;intestine: 32.8;skin 1: 52.1" "Cell type enhanced" "Detected in many" "Enterocytes: 268.4;Epididymal efferent duct absorptive cells: 100.9;Esophageal apical cells: 508.1;Esophageal suprabasal cells: 243.0;Oocytes: 101.3;Respiratory ciliated cells: 138.3;Respiratory secretory cells: 172.5" "Cell type enhanced" "Detected in many" "endothelial cell: 78.0" "Cancer enhanced" "Detected in all" "Breast Invasive Carcinoma (TCGA): 70.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 3.5;eosinophil: 6.7;memory B-cell: 10.9;naive B-cell: 6.9" "Group enriched" "Detected in many" 5 "B-cells: 10.9;granulocytes: 6.7" "Cancer enhanced" "Detected in many" "breast cancer: 20.5;colorectal cancer: 11.3;Gastric cancer: 11.7" "Breast - Breast glandular cells, Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Pituitary gland - Corticotropes, Prostate - Urothelial cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046644 Approved Nucleoplasm,Nucleoli NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 77: Intestine - Digestion" "Cluster 15: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 85: Squamous epithelial cells - Keratinization" "Nucleoplasm, Nucleoli" "HPA046644: " "unprognostic (5.30e-2)" "unprognostic (8.91e-2)" "unprognostic (5.22e-2)" "unprognostic (3.28e-3)" "unprognostic (8.48e-2)" "unprognostic (3.11e-2)" "unprognostic (2.10e-1)" "unprognostic (1.25e-1)" "unprognostic (8.17e-2)" "validated prognostic favorable (3.22e-6)" "validated prognostic favorable (8.06e-4)" "unprognostic (1.03e-1)" "unprognostic (1.99e-1)" "unprognostic (1.89e-2)" "unprognostic (2.82e-2)" "unprognostic (2.57e-3)" "unprognostic (1.21e-1)" "unprognostic (3.46e-1)" "unprognostic (7.78e-2)" "unprognostic (1.73e-2)" "unprognostic (2.48e-1)" "unprognostic (3.16e-3)" "unprognostic (8.82e-2)" "unprognostic (2.52e-1)" "unprognostic (1.80e-3)" "unprognostic (7.27e-2)" "potential prognostic favorable (9.92e-4)" "unprognostic (1.87e-1)" "unprognostic (5.12e-2)" "unprognostic (3.64e-1)" DEK D6S231E ENSG00000124795 "DEK proto-oncogene" P35659 6 18223860-18264548 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Chromatin regulator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythrocyte progenitors: 759.6;Monocyte progenitors: 816.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015226, HPA054505, HPA057799" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 1: T-cells - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 27: Non-specific - Cell proliferation" 32 Nucleoplasm Cytosol "CAB015226: , HPA054505: , HPA057799: " "unprognostic (3.96e-1)" "unprognostic (1.16e-1)" "unprognostic (1.71e-1)" "unprognostic (1.16e-1)" "unprognostic (1.42e-1)" "unprognostic (2.01e-3)" "unprognostic (3.08e-1)" "unprognostic (6.80e-2)" "unprognostic (1.96e-2)" "potential prognostic unfavorable (1.84e-6)" "potential prognostic favorable (1.05e-5)" "unprognostic (1.51e-1)" "unprognostic (2.80e-3)" "unprognostic (3.66e-3)" "unprognostic (3.88e-3)" "unprognostic (1.20e-2)" "unprognostic (1.08e-3)" "unprognostic (1.99e-1)" "unprognostic (4.15e-2)" "unprognostic (2.71e-2)" "unprognostic (1.54e-1)" "unprognostic (1.15e-3)" "unprognostic (1.60e-1)" "unprognostic (1.29e-2)" "unprognostic (4.26e-2)" "unprognostic (6.16e-2)" "unprognostic (2.99e-2)" "unprognostic (6.28e-2)" "unprognostic (1.40e-1)" "unprognostic (1.18e-1)" "unprognostic (1.06e-1)" DELE1 "DELE, KIAA0141" ENSG00000081791 "DAP3 binding cell death enhancer 1" Q14154 5 141923855-141942047 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, DNA damage" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036548, HPA061490" Uncertain Uncertain "Nucleoplasm,Golgi apparatus" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 35: Non-specific - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 102: Non-specific - Mixed function" 6 Nucleoplasm "Golgi apparatus" "HPA036548: , HPA061490: " "unprognostic (1.57e-2)" "unprognostic (7.39e-2)" "unprognostic (1.58e-2)" "unprognostic (2.08e-3)" "unprognostic (9.88e-2)" "unprognostic (3.75e-2)" "unprognostic (3.41e-1)" "unprognostic (3.52e-1)" "unprognostic (4.70e-3)" "potential prognostic favorable (6.38e-8)" "unprognostic (1.66e-2)" "unprognostic (3.77e-3)" "unprognostic (1.45e-2)" "unprognostic (2.55e-2)" "unprognostic (1.06e-1)" "unprognostic (2.60e-3)" "unprognostic (2.53e-1)" "unprognostic (1.34e-3)" "unprognostic (3.35e-1)" "unprognostic (2.29e-1)" "unprognostic (2.18e-2)" "unprognostic (3.06e-1)" "unprognostic (2.90e-2)" "unprognostic (2.65e-1)" "unprognostic (1.02e-1)" "unprognostic (1.64e-1)" "unprognostic (1.46e-1)" "unprognostic (8.87e-2)" "unprognostic (9.97e-2)" DENND10 FAM45A ENSG00000119979 "DENN domain containing 10" Q8TCE6 10 119104086-119137984 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 181.0;Neutrophils: 148.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061569 Approved Vesicles NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 24 Vesicles "HPA061569: " "unprognostic (1.26e-1)" "unprognostic (2.92e-3)" "unprognostic (1.36e-2)" "unprognostic (2.38e-1)" "unprognostic (1.47e-1)" "unprognostic (2.26e-1)" "unprognostic (3.77e-3)" "unprognostic (1.29e-1)" "unprognostic (2.23e-1)" "potential prognostic favorable (2.14e-6)" "unprognostic (1.67e-2)" "unprognostic (3.75e-1)" "unprognostic (4.12e-3)" "unprognostic (6.69e-3)" "unprognostic (1.36e-1)" "unprognostic (1.72e-1)" "unprognostic (3.35e-1)" "unprognostic (3.87e-1)" "unprognostic (9.95e-3)" "unprognostic (1.01e-2)" "unprognostic (2.46e-2)" "unprognostic (5.30e-2)" "unprognostic (7.93e-2)" "unprognostic (1.34e-1)" "unprognostic (1.92e-1)" "unprognostic (1.87e-1)" "unprognostic (1.59e-1)" "unprognostic (2.87e-1)" "unprognostic (3.03e-1)" DENND11 "KIAA1147, LCHN" ENSG00000257093 "DENN domain containing 11" A4D1U4 7 141656728-141702166 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 48.5;Bergmann glia: 47.1;Brain excitatory neurons: 46.8;Brain inhibitory neurons: 47.5;Choroid plexus epithelial cells: 44.2;Distal convoluted tubule cells: 36.5;Loop of henle epithelial cells: 36.1;Microglia: 184.9;Oligodendrocyte progenitor cells: 39.8;Oligodendrocytes: 100.6;Papillary tip epithelial cells: 29.7;Proximal tubule cells: 46.5;Renal collecting duct intercalated cells: 26.7;Renal collecting duct principal cells: 31.3;Renal connecting tubule cells: 34.4" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 227.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "basophil: 1.7" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.7" "Low cancer specificity" "Detected in many" "Lung - Fibroblasts_1, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029467, HPA061437" Approved Approved "Golgi apparatus" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 4 "Golgi apparatus" "HPA029467: , HPA061437: " "unprognostic (1.00e-3)" "unprognostic (2.65e-2)" "unprognostic (6.48e-2)" "potential prognostic favorable (9.12e-4)" "potential prognostic favorable (1.46e-8)" "unprognostic (1.28e-2)" "unprognostic (1.44e-1)" "unprognostic (1.47e-1)" "unprognostic (9.55e-2)" "unprognostic (1.35e-2)" "unprognostic (7.53e-3)" "unprognostic (7.22e-2)" "unprognostic (2.82e-2)" "unprognostic (1.26e-1)" DENND1A "FAM31A, FLJ21129, KIAA1608" ENSG00000119522 "DENN domain containing 1A" Q8TEH3 9 123379654-123930152 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 675.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 8 "dendritic cells: 11.4;granulocytes: 14.0;monocytes: 19.9" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Spleen - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020481 Approved Vesicles,Cytosol NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 13 "Vesicles, Cytosol" "HPA020481: " "unprognostic (2.24e-3)" "unprognostic (1.88e-2)" "unprognostic (3.46e-1)" "unprognostic (2.20e-1)" "unprognostic (5.20e-2)" "unprognostic (3.46e-2)" "unprognostic (4.45e-2)" "unprognostic (2.74e-1)" "unprognostic (4.63e-2)" "unprognostic (3.69e-1)" "validated prognostic favorable (1.99e-7)" "validated prognostic favorable (5.42e-5)" "unprognostic (1.05e-1)" "unprognostic (4.95e-2)" "unprognostic (2.43e-1)" "unprognostic (3.46e-3)" "potential prognostic unfavorable (1.62e-4)" "unprognostic (5.18e-2)" "unprognostic (7.26e-2)" "unprognostic (2.56e-2)" "unprognostic (8.89e-2)" "unprognostic (1.05e-1)" "unprognostic (6.02e-3)" "unprognostic (1.22e-2)" "unprognostic (4.17e-2)" "unprognostic (2.15e-2)" "unprognostic (1.82e-2)" "unprognostic (2.71e-2)" "unprognostic (1.47e-1)" "unprognostic (8.96e-2)" "unprognostic (1.91e-1)" DENND1B "C1orf218, FAM31B, FLJ20054, MGC27044" ENSG00000213047 "DENN domain containing 1B" Q6P3S1 1 197504748-197775696 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Guanine-nucleotide releasing factor" Asthma "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ocular epithelial cells: 539.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skeletal muscle - Skeletal myocytes, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042586 Uncertain Supported "Nuclear speckles,Cytosol" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 100: Stratified epithelial cells - Barrier functions" Cytosol "Nuclear speckles" "HPA042586: " "unprognostic (1.02e-1)" "unprognostic (2.56e-1)" "unprognostic (2.33e-2)" "unprognostic (4.83e-2)" "unprognostic (8.64e-2)" "unprognostic (3.37e-1)" "unprognostic (2.19e-1)" "unprognostic (1.89e-1)" "unprognostic (4.24e-2)" "unprognostic (3.85e-3)" "unprognostic (2.28e-3)" "unprognostic (8.55e-2)" "unprognostic (1.16e-1)" "unprognostic (2.11e-1)" "unprognostic (1.31e-1)" "unprognostic (4.57e-2)" "unprognostic (1.68e-1)" "unprognostic (1.32e-1)" "unprognostic (5.01e-2)" "unprognostic (3.15e-1)" "unprognostic (2.66e-3)" "potential prognostic unfavorable (9.39e-4)" "unprognostic (6.49e-2)" "unprognostic (1.37e-1)" "unprognostic (3.27e-1)" "unprognostic (4.43e-2)" "unprognostic (2.37e-1)" "unprognostic (4.87e-2)" "unprognostic (1.34e-1)" "unprognostic (2.33e-2)" "unprognostic (3.92e-2)" DENND1C "FAM31C, FLJ22757" ENSG00000205744 "DENN domain containing 1C" Q8IV53 19 6467207-6482557 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.0;intestine: 13.8;lymphoid tissue: 34.2" "Cell type enhanced" "Detected in many" "B-cells: 35.4;cDC: 19.6;Hofbauer cells: 23.3;Innate lymphoid cells: 24.2;Microglia: 26.4;monocytes: 23.5;Neutrophil progenitors: 28.4;Neutrophils: 51.8;NK-cells: 63.0;pDCs: 23.3;T-cells: 54.1;Thymocytes: 28.8" "Group enriched" "Detected in some" 19 "central nervous system macrophage: 30.9;leukocyte: 58.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 29 "Leukemia: 21.7;lymphoma: 25.3;Myeloma: 8.7" "Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Colon - T-cells, Prostate - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA042758, HPA042839" Enhanced Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 1 Cytosol "Nucleoplasm, Centrosome" "HPA042758: , HPA042839: " "unprognostic (7.95e-2)" "unprognostic (1.94e-2)" "unprognostic (2.78e-2)" "unprognostic (1.01e-2)" "unprognostic (3.79e-2)" "unprognostic (1.74e-1)" "unprognostic (1.14e-1)" "unprognostic (1.10e-1)" "unprognostic (1.79e-3)" "unprognostic (3.59e-1)" "unprognostic (5.16e-2)" "unprognostic (2.03e-1)" "unprognostic (1.16e-1)" "unprognostic (1.33e-1)" "unprognostic (2.86e-1)" "unprognostic (1.63e-3)" "unprognostic (1.01e-1)" "unprognostic (6.19e-2)" "unprognostic (1.67e-1)" "unprognostic (2.10e-1)" "unprognostic (1.73e-1)" "unprognostic (7.04e-2)" "unprognostic (7.90e-2)" "unprognostic (1.71e-1)" "unprognostic (9.14e-3)" "unprognostic (7.64e-3)" "unprognostic (5.21e-2)" "unprognostic (1.68e-1)" "unprognostic (9.34e-2)" "unprognostic (2.36e-1)" "unprognostic (1.11e-1)" DENND2A "FAM31D, KIAA1277" ENSG00000146966 "DENN domain containing 2A" Q9ULE3 7 140518420-140673993 "Predicted intracellular proteins" "Protein transport, Transport" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 567.7;Fibro-adipogenic progenitors: 360.4;Gonadotrophs: 209.8;Granulosa cells: 278.2;Hepatic stellate cells: 219.5;Lactotrophs: 373.5;Loop of henle epithelial cells: 226.1;Retinal horizontal cells: 575.0;Retinal pigment epithelial cells: 306.9;Somatotrophs: 633.1;Thyrotrophs: 702.0" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 377.7;pericyte: 336.9" "Cancer enriched" "Detected in all" 7 "Glioblastoma Multiforme (TCGA): 74.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Minor Salivary Gland - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 43: Hindbrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 2 "unprognostic (3.70e-2)" "unprognostic (2.90e-1)" "unprognostic (9.52e-2)" "unprognostic (1.31e-1)" "unprognostic (4.72e-2)" "unprognostic (4.46e-1)" "unprognostic (1.28e-3)" "potential prognostic unfavorable (9.27e-5)" "unprognostic (4.43e-2)" "unprognostic (3.11e-2)" "unprognostic (8.79e-2)" "unprognostic (3.51e-1)" "potential prognostic unfavorable (5.48e-4)" "unprognostic (1.23e-1)" "unprognostic (2.68e-1)" "unprognostic (1.57e-1)" "unprognostic (3.10e-2)" "unprognostic (6.33e-3)" "unprognostic (7.96e-2)" "unprognostic (2.28e-1)" "unprognostic (2.75e-1)" "unprognostic (1.64e-3)" "unprognostic (1.55e-2)" "unprognostic (4.58e-2)" "unprognostic (1.03e-2)" "unprognostic (1.22e-1)" "unprognostic (2.31e-1)" "unprognostic (3.47e-2)" "unprognostic (1.10e-1)" "unprognostic (3.53e-2)" "unprognostic (1.02e-2)" DENND2B "HTS1, p126, ST5" ENSG00000166444 "DENN domain containing 2B" P78524 11 8693351-8910951 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 453.4;Rod photoreceptor cells: 399.8" "Cell type enhanced" "Detected in all" "pericyte: 460.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "non-classical monocyte: 2.9" "Lineage enriched" "Detected in single" 4 "monocytes: 2.9" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells, Breast - Breast myoepithelial cells, Prostate - Smooth muscle cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046796 Approved Approved Nucleoplasm NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 75: Ovary - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 79: Photoreceptor cells - Phototransduction" 10 Nucleoplasm "HPA046796: " "unprognostic (7.01e-2)" "unprognostic (6.09e-2)" "unprognostic (1.71e-2)" "unprognostic (2.86e-1)" "unprognostic (1.94e-1)" "unprognostic (1.56e-2)" "unprognostic (3.90e-2)" "unprognostic (9.44e-2)" "unprognostic (1.55e-1)" "unprognostic (7.27e-2)" "unprognostic (2.93e-1)" "unprognostic (1.71e-1)" "unprognostic (4.48e-2)" "unprognostic (1.99e-2)" "unprognostic (1.85e-2)" "unprognostic (5.06e-2)" "unprognostic (1.05e-1)" "unprognostic (2.43e-2)" "unprognostic (1.91e-1)" "unprognostic (6.58e-3)" "unprognostic (4.46e-3)" "unprognostic (2.26e-1)" "unprognostic (8.14e-2)" "unprognostic (8.38e-2)" "unprognostic (1.65e-1)" "unprognostic (1.11e-1)" "unprognostic (5.03e-2)" "unprognostic (4.16e-1)" "unprognostic (6.88e-2)" DENND2C "dJ1156J9.1, DKFZp686G0351, DKFZp779P1149, FLJ37099, RP5-1156J9.1" ENSG00000175984 "DENN domain containing 2C" Q68D51 1 114582848-114670422 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 16.6;skeletal muscle: 39.0" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 896.4;Endometrial luminal cells: 707.9;Endometrial secretory cells: 520.5;Epididymal basal cells: 730.0;Esophageal apical cells: 1927.8;Esophageal basal cells: 539.7;Esophageal suprabasal cells: 996.6;Myonuclei: 1580.9;Ocular epithelial cells: 1318.6;Respiratory basal cells: 496.6;Suprabasal keratinocytes: 920.8;Urothelial cells: 1086.6" "Cell type enhanced" "Detected in many" "endothelial cell: 152.0" "Group enriched" "Detected in some" 5 "Bladder Urothelial Carcinoma (TCGA): 2.7;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 6.5;Head and Neck Squamous Cell Carcinoma (TCGA): 6.3;Lung Squamous Cell Carcinoma (TCGA): 3.9;Testicular Germ Cell Tumor (TCGA): 2.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 3.0" "Lineage enriched" "Detected in single" 12 "granulocytes: 3.0" "Cancer enhanced" "Detected in many" "Bone cancer: 10.3;Myeloma: 10.2" "Skeletal muscle - Skeletal myocytes, Testis - Spermatocytes" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA029935, HPA054955" Uncertain Enhanced Nucleoplasm NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" Nucleoplasm "HPA029935: , HPA054955: " "unprognostic (1.40e-1)" "unprognostic (4.09e-1)" "unprognostic (1.69e-1)" "unprognostic (2.05e-1)" "unprognostic (1.12e-1)" "potential prognostic favorable (3.61e-5)" "unprognostic (3.95e-2)" "unprognostic (1.72e-1)" "unprognostic (1.73e-2)" "unprognostic (1.66e-1)" "potential prognostic unfavorable (9.32e-5)" "potential prognostic favorable (7.27e-4)" "unprognostic (2.98e-1)" DENND2D "FLJ22457, RP5-1180E21.2" ENSG00000162777 "DENN domain containing 2D" Q9H6A0 1 111185969-111204535 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 87.8" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 219.8;Esophageal suprabasal cells: 99.3;Hofbauer cells: 108.2;Late primary spermatocytes: 76.9;Late spermatids: 88.7;NK-cells: 111.7" "Cell type enriched" "Detected in some" 9 "leukocyte: 96.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "gdT-cell: 237.2;MAIT T-cell: 204.6;memory CD4 T-cell: 172.4;memory CD8 T-cell: 243.8;naive CD4 T-cell: 266.2;naive CD8 T-cell: 257.5;NK-cell: 279.1;T-reg: 79.7" "Group enriched" "Detected in all" 6 "NK-cells: 279.1;T-cells: 266.2" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Pituitary gland - Somatotropes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA043630, HPA048642" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 27: T-cells - Unknown function" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 3 "Nucleoplasm, Cytosol" "HPA043630: , HPA048642: " "unprognostic (1.61e-1)" "unprognostic (3.24e-1)" "unprognostic (2.25e-1)" "unprognostic (1.39e-1)" "unprognostic (4.80e-3)" "unprognostic (1.49e-1)" "unprognostic (8.21e-3)" "unprognostic (1.95e-2)" "unprognostic (4.87e-3)" "unprognostic (2.87e-2)" "potential prognostic favorable (1.82e-4)" "unprognostic (1.16e-1)" "unprognostic (6.94e-2)" "unprognostic (5.54e-2)" "unprognostic (1.87e-1)" "unprognostic (3.72e-1)" "unprognostic (1.84e-2)" "unprognostic (1.22e-2)" "unprognostic (1.95e-1)" "unprognostic (1.08e-1)" "unprognostic (6.71e-3)" "unprognostic (3.98e-2)" "unprognostic (1.17e-1)" "unprognostic (1.99e-1)" "unprognostic (7.06e-2)" "unprognostic (2.25e-1)" "unprognostic (4.49e-1)" "unprognostic (2.97e-2)" "unprognostic (2.77e-2)" "unprognostic (3.32e-1)" "unprognostic (9.20e-2)" DENND3 KIAA0870 ENSG00000105339 "DENN domain containing 3" A2RUS2 8 141117278-141195808 "Predicted intracellular proteins, Predicted membrane proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 100.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 301.6;Epicardial cells: 197.9;Microglia: 303.4;monocytes: 136.0;Neutrophil progenitors: 271.7;Neutrophils: 805.4" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 365.5;endothelial cell: 216.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 34.7;neutrophil: 40.5" "Group enriched" "Detected in many" 5 "granulocytes: 40.5;monocytes: 10.1" "Cancer enhanced" "Detected in all" "Leukemia: 67.4" "Spleen - Neutrophils_2, Testis - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA024491, HPA041668" Approved Approved Vesicles,Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 6: Leukemia - Signal transduction" "Cluster 29: Neutrophils - Innate immune cellular maintenance" "Vesicles, Cytosol" "HPA024491: , HPA041668: " "unprognostic (2.87e-3)" "unprognostic (1.14e-1)" "unprognostic (5.78e-3)" "unprognostic (1.98e-2)" "unprognostic (1.83e-1)" "unprognostic (3.06e-2)" "unprognostic (3.39e-2)" "unprognostic (4.16e-2)" "unprognostic (6.93e-2)" "unprognostic (7.57e-3)" "unprognostic (2.39e-2)" "unprognostic (2.15e-2)" "unprognostic (1.98e-2)" "unprognostic (4.09e-2)" "unprognostic (4.72e-3)" "unprognostic (4.42e-2)" "unprognostic (1.60e-1)" "unprognostic (1.21e-2)" "unprognostic (1.68e-1)" "unprognostic (2.71e-2)" "unprognostic (2.47e-2)" "unprognostic (7.73e-3)" "potential prognostic unfavorable (8.75e-4)" "unprognostic (3.77e-2)" "unprognostic (4.21e-1)" "unprognostic (7.71e-3)" "unprognostic (3.44e-1)" "unprognostic (1.57e-1)" "unprognostic (1.32e-1)" "unprognostic (2.18e-2)" "unprognostic (5.53e-2)" DENND4A "IRLB, MYCPBP" ENSG00000174485 "DENN domain containing 4A" Q7Z401 15 65658046-65792293 "Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 54.8" "Cell type enhanced" "Detected in all" "Mast cells: 1001.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065343 Uncertain Approved "Nucleoplasm,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 24: Non-specific - Transcription" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 35: Non-specific - DNA binding" "Cluster 55: Lymphoma - Immune response" "Cluster 103: Non-specific - Basic cellular processes" 33 "Nucleoli rim" "Nucleoplasm, Mitotic chromosome" "HPA065343: " "unprognostic (2.98e-2)" "unprognostic (9.94e-2)" "unprognostic (2.14e-2)" "unprognostic (2.45e-1)" "unprognostic (2.14e-1)" "unprognostic (5.83e-3)" "unprognostic (1.96e-1)" "unprognostic (1.77e-2)" "unprognostic (2.05e-1)" "unprognostic (6.76e-3)" "validated prognostic favorable (5.07e-4)" "validated prognostic favorable (9.39e-5)" "unprognostic (2.20e-1)" "unprognostic (2.35e-1)" "unprognostic (1.96e-2)" "unprognostic (2.84e-2)" "unprognostic (4.46e-1)" "unprognostic (2.26e-1)" "unprognostic (2.55e-1)" "unprognostic (1.48e-1)" "unprognostic (1.85e-2)" "unprognostic (1.92e-1)" "unprognostic (2.28e-3)" "unprognostic (1.73e-1)" "unprognostic (1.72e-2)" "unprognostic (1.88e-1)" "unprognostic (1.40e-1)" "unprognostic (1.06e-1)" "unprognostic (9.93e-2)" "unprognostic (2.41e-1)" "unprognostic (5.16e-2)" DENND4B KIAA0476 ENSG00000198837 "DENN domain containing 4B" O75064 1 153929501-153946718 "Predicted intracellular proteins, Predicted membrane proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglia: 64.9;Neutrophils: 61.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040188, HPA071133" Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 1 "Nucleoplasm, Golgi apparatus" "HPA040188: , HPA071133: " "unprognostic (1.72e-1)" "unprognostic (1.37e-1)" "unprognostic (3.49e-3)" "unprognostic (3.45e-2)" "unprognostic (4.47e-2)" "unprognostic (4.83e-2)" "unprognostic (1.67e-1)" "unprognostic (1.34e-2)" "unprognostic (2.07e-2)" "unprognostic (3.85e-2)" "unprognostic (3.58e-1)" "unprognostic (6.33e-2)" "unprognostic (1.61e-1)" "potential prognostic unfavorable (1.52e-4)" "unprognostic (1.31e-2)" "unprognostic (3.87e-1)" "unprognostic (3.37e-2)" "unprognostic (1.22e-1)" "unprognostic (3.12e-2)" "unprognostic (5.23e-1)" "unprognostic (3.21e-3)" "unprognostic (2.36e-2)" "unprognostic (7.05e-3)" "unprognostic (3.81e-1)" "unprognostic (8.38e-2)" "unprognostic (6.46e-2)" "unprognostic (4.24e-2)" "unprognostic (3.09e-1)" "unprognostic (2.75e-1)" "unprognostic (1.84e-2)" "unprognostic (2.01e-1)" DENND4C "bA513M16.3, C9orf55, C9orf55B, FLJ20686, RAB10GEF" ENSG00000137145 "DENN domain containing 4C" Q5VZ89 9 19230435-19374281 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014917, HPA015096" Approved Supported "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 77: Intestine - Digestion" "Cluster 15: Non-specific - Transcription" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 25 "Golgi apparatus, Vesicles, Cytosol" "HPA014917: , HPA015096: " "unprognostic (1.60e-2)" "unprognostic (2.22e-2)" "unprognostic (5.08e-1)" "unprognostic (5.32e-3)" "unprognostic (1.78e-1)" "unprognostic (2.46e-2)" "unprognostic (7.43e-2)" "unprognostic (2.31e-2)" "unprognostic (3.77e-1)" "unprognostic (5.02e-2)" "validated prognostic favorable (9.02e-9)" "validated prognostic favorable (2.87e-4)" "unprognostic (1.75e-2)" "unprognostic (1.62e-2)" "unprognostic (2.52e-1)" "unprognostic (4.32e-1)" "unprognostic (5.32e-2)" "unprognostic (7.73e-2)" "unprognostic (4.08e-1)" "unprognostic (3.33e-1)" "unprognostic (9.90e-3)" "unprognostic (4.06e-2)" "unprognostic (1.59e-1)" "unprognostic (1.89e-1)" "unprognostic (1.03e-2)" "unprognostic (6.84e-2)" "unprognostic (8.06e-2)" "unprognostic (3.32e-1)" "unprognostic (4.13e-1)" "unprognostic (8.17e-2)" "unprognostic (3.76e-2)" DENND5A "FLJ22354, FLJ33829, FLJ43455, KIAA1091, RAB6IP1" ENSG00000184014 "DENN domain containing 5A" Q6IQ26 11 9138825-9265959 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Guanine-nucleotide releasing factor" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Neutrophils: 4577.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 96.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pituitary gland - Endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052923, HPA055009" Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 1 "Golgi apparatus, Vesicles" "HPA052923: , HPA055009: " "unprognostic (1.12e-2)" "unprognostic (5.27e-2)" "unprognostic (2.14e-1)" "unprognostic (1.22e-1)" "unprognostic (1.06e-1)" "unprognostic (2.48e-1)" "unprognostic (1.55e-1)" "unprognostic (1.22e-1)" "unprognostic (4.31e-2)" "unprognostic (7.31e-2)" "potential prognostic favorable (3.38e-4)" "unprognostic (5.38e-2)" "unprognostic (1.13e-2)" "potential prognostic unfavorable (2.14e-5)" "unprognostic (5.09e-2)" "unprognostic (1.90e-2)" "unprognostic (3.01e-2)" "unprognostic (6.23e-2)" "unprognostic (2.01e-1)" "unprognostic (1.70e-1)" "unprognostic (1.44e-1)" "unprognostic (2.87e-1)" "unprognostic (6.22e-3)" "unprognostic (6.21e-2)" "unprognostic (3.69e-1)" "unprognostic (9.55e-2)" "unprognostic (1.20e-1)" "unprognostic (4.58e-3)" "unprognostic (6.02e-2)" "unprognostic (1.60e-1)" "unprognostic (3.23e-1)" DENND5B MGC24039 ENSG00000170456 "DENN domain containing 5B" Q6ZUT9 12 31382226-31591136 "Predicted intracellular proteins, Predicted membrane proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Lactotrophs: 482.6;Myonuclei: 456.2;Thyrotrophs: 468.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.4;naive B-cell: 1.6" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in all" "testis cancer: 52.8" "Adrenal gland - Adrenal cortex cells, Pituitary gland - Lactotropes, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038865 Approved Approved Microtubules NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 61: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 87: B-cells - Adaptive immunity: Humoral response" Microtubules "HPA038865: " "unprognostic (2.17e-1)" "unprognostic (2.46e-1)" "unprognostic (4.55e-3)" "unprognostic (1.92e-2)" "unprognostic (2.65e-2)" "unprognostic (1.62e-1)" "unprognostic (1.06e-1)" "potential prognostic favorable (4.91e-4)" "unprognostic (1.53e-1)" "unprognostic (2.44e-2)" "potential prognostic favorable (1.63e-4)" "unprognostic (1.39e-2)" "unprognostic (6.95e-2)" "unprognostic (1.81e-3)" "unprognostic (2.12e-2)" "unprognostic (1.08e-2)" "unprognostic (1.16e-1)" "unprognostic (1.87e-1)" "unprognostic (4.98e-2)" "unprognostic (7.39e-2)" "unprognostic (1.42e-1)" "unprognostic (1.66e-1)" "unprognostic (7.12e-2)" "unprognostic (2.42e-1)" "unprognostic (6.08e-2)" "unprognostic (1.35e-1)" "unprognostic (7.21e-2)" "unprognostic (5.21e-3)" "unprognostic (8.69e-2)" "unprognostic (3.49e-2)" "unprognostic (8.25e-2)" DENND6A "AFI1A, FAM116A, FLJ34969" ENSG00000174839 "DENN domain containing 6A" Q8IWF6 3 57625454-57693077 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 250.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 18.6" "Lineage enriched" "Detected in all" 5 "granulocytes: 18.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062618, HPA069725, HPA071711" Approved Supported Vesicles NA NA "Cluster 1: T-cells - Unknown function" "Cluster 49: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 9: T-cells - Adaptive immunity: Regulation" 5 Vesicles "HPA062618: , HPA069725: , HPA071711: " "unprognostic (9.15e-3)" "unprognostic (1.68e-1)" "unprognostic (3.03e-1)" "unprognostic (3.98e-2)" "unprognostic (2.41e-3)" "unprognostic (3.68e-1)" "unprognostic (4.62e-1)" "unprognostic (1.34e-1)" "unprognostic (1.10e-3)" "potential prognostic favorable (1.64e-4)" "unprognostic (4.46e-3)" "potential prognostic favorable (9.76e-4)" "unprognostic (1.60e-3)" "unprognostic (4.49e-1)" "unprognostic (9.94e-3)" "unprognostic (3.02e-2)" "unprognostic (1.08e-1)" "unprognostic (4.31e-2)" "unprognostic (1.27e-1)" "unprognostic (4.05e-2)" "unprognostic (7.00e-3)" "unprognostic (5.49e-2)" "unprognostic (2.05e-2)" "unprognostic (8.89e-3)" "unprognostic (8.48e-2)" "unprognostic (2.18e-1)" "unprognostic (8.85e-2)" "unprognostic (5.49e-3)" "unprognostic (2.97e-1)" DENND6B "AFI1B, FAM116B, MGC33692" ENSG00000205593 "DENN domain containing 6B" Q8NEG7 22 50309030-50327012 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.0" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 81.6;Ependymal cells: 114.9;Epididymal efferent duct ciliated cells: 96.1;Fallopian tube ciliated cells: 101.0;Late spermatids: 129.3;Megakaryocytes: 191.6;Respiratory ciliated cells: 180.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Lung - Respiratory ciliated cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018934, HPA021653, HPA029570" Uncertain Approved "Plasma membrane" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 64: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 107: Ciliated cells - Cilia assembly & function" "Plasma membrane" "HPA018934: , HPA021653: , HPA029570: " "unprognostic (6.07e-3)" "unprognostic (2.13e-1)" "unprognostic (2.67e-1)" "unprognostic (4.88e-3)" "unprognostic (8.26e-2)" "unprognostic (2.10e-1)" "unprognostic (8.59e-2)" "unprognostic (1.20e-1)" "unprognostic (3.57e-1)" "unprognostic (1.16e-2)" "unprognostic (7.66e-3)" "potential prognostic favorable (2.99e-4)" "potential prognostic unfavorable (6.81e-5)" "unprognostic (4.79e-2)" "unprognostic (3.48e-1)" "unprognostic (6.25e-2)" "unprognostic (2.79e-1)" "unprognostic (4.96e-3)" "unprognostic (3.44e-3)" "unprognostic (6.44e-2)" "unprognostic (3.94e-2)" "unprognostic (4.24e-1)" "unprognostic (1.89e-1)" "unprognostic (2.64e-1)" "unprognostic (1.33e-1)" "unprognostic (6.50e-2)" "unprognostic (1.96e-1)" "unprognostic (1.20e-1)" "unprognostic (2.13e-1)" DENR "DRP, DRP1, SMAP-3" ENSG00000139726 "Density regulated re-initiation and release factor" O43583 12 122752824-122771064 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 228.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021783 Approved Approved Cytosol NA NA 210000 "Cluster 41: Basophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 1: Neurons - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 8 Cytosol "HPA021783: " "unprognostic (1.15e-2)" "unprognostic (2.49e-2)" "unprognostic (1.12e-2)" "unprognostic (8.73e-3)" "unprognostic (1.30e-1)" "unprognostic (2.09e-1)" "unprognostic (2.25e-1)" "unprognostic (4.66e-2)" "unprognostic (4.95e-3)" "potential prognostic unfavorable (2.41e-5)" "unprognostic (1.67e-3)" "unprognostic (1.33e-1)" "unprognostic (2.04e-1)" "validated prognostic unfavorable (3.89e-8)" "validated prognostic unfavorable (6.83e-4)" "potential prognostic unfavorable (4.12e-4)" "unprognostic (2.47e-3)" "unprognostic (8.15e-2)" "unprognostic (4.71e-2)" "unprognostic (1.92e-1)" "unprognostic (1.36e-3)" "unprognostic (1.27e-1)" "unprognostic (1.38e-1)" "unprognostic (1.12e-2)" "unprognostic (1.87e-2)" "unprognostic (2.17e-2)" "unprognostic (2.01e-2)" "unprognostic (1.95e-1)" "unprognostic (4.73e-1)" "unprognostic (6.10e-2)" "unprognostic (8.48e-2)" DEPDC1 "DEP.8, DEPDC1A, FLJ20354, SDP35" ENSG00000024526 "DEP domain containing 1" Q5TB30 1 68474152-68497221 "Predicted intracellular proteins" "Transcription, Transcription regulation" "GTPase activation, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.7;lymphoid tissue: 7.5;testis: 7.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 23.9;Early primary spermatocytes: 68.9;Early spermatids: 37.1;Enteric transient amplifying cells: 30.7;Erythrocyte progenitors: 54.9;Esophageal basal cells: 27.0;Extravillous trophoblasts: 38.7;Late primary spermatocytes: 90.0;Late spermatids: 115.6;Megakaryocyte progenitors: 45.0;Migrating cytotrophoblasts: 32.4;Monocyte progenitors: 60.8" "Cell type enhanced" "Detected in some" "MGE interneuron: 5.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Thyroid gland - Mitotic cells (Thyroid)" "Not detected" "Not detected" "Not detected" "Not detected" CAB017845 Approved Supported "Nucleoplasm,Nucleoli fibrillar center" NA Yes "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 37: Non-specific - mRNA processing" "Cluster 27: Non-specific - Cell proliferation" 2 Nucleoplasm "Nucleoli fibrillar center" "CAB017845: " "potential prognostic unfavorable (7.42e-4)" "unprognostic (3.42e-1)" "unprognostic (2.09e-1)" "unprognostic (1.50e-1)" "unprognostic (5.92e-3)" "unprognostic (8.87e-2)" "unprognostic (3.46e-1)" "unprognostic (3.96e-2)" "unprognostic (8.85e-2)" "potential prognostic unfavorable (5.72e-6)" "validated prognostic unfavorable (1.66e-6)" "validated prognostic unfavorable (7.37e-9)" "validated prognostic unfavorable (8.75e-5)" "validated prognostic unfavorable (1.72e-4)" "unprognostic (1.40e-2)" "unprognostic (1.49e-1)" "unprognostic (2.14e-1)" "unprognostic (4.40e-1)" "potential prognostic unfavorable (7.83e-6)" "unprognostic (1.27e-3)" "unprognostic (2.46e-1)" "unprognostic (2.40e-3)" "unprognostic (1.80e-1)" "unprognostic (1.09e-2)" "unprognostic (8.38e-2)" "unprognostic (1.75e-1)" "unprognostic (5.39e-2)" DEPDC1B "BRCC3, XTP1" ENSG00000035499 "DEP domain containing 1B" Q8WUY9 5 60596912-60700190 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.5;gallbladder: 19.7;lymphoid tissue: 19.3;testis: 11.8" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 150.8;Early primary spermatocytes: 71.6;Endometrial glandular cells: 74.0;Endometrial luminal cells: 85.5;Epididymal clear cells: 67.4;Erythrocyte progenitors: 75.4;Late primary spermatocytes: 47.5;Megakaryocyte progenitors: 55.4;Monocyte progenitors: 118.2;Neutrophil progenitors: 78.5;Syncytiotrophoblasts: 191.7" "Cell type enhanced" "Detected in many" "hippocampal dentate gyrus: 29.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "T-reg: 3.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Kidney - Intercalated cells, Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA038255, HPA072558" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA Yes "Cluster 5: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 30: White matter - Myelination" "Cluster 15: Kidney cancer - Membrane components" "Cluster 27: Non-specific - Cell proliferation" 15 "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA038255: , HPA072558: " "unprognostic (2.29e-2)" "unprognostic (6.01e-2)" "unprognostic (3.81e-2)" "unprognostic (4.11e-2)" "unprognostic (6.74e-3)" "unprognostic (2.27e-1)" "unprognostic (2.78e-1)" "unprognostic (3.82e-2)" "unprognostic (5.03e-2)" "unprognostic (1.46e-3)" "validated prognostic unfavorable (4.79e-6)" "validated prognostic unfavorable (1.83e-4)" "potential prognostic unfavorable (3.03e-8)" "validated prognostic unfavorable (8.35e-5)" "validated prognostic unfavorable (8.56e-6)" "validated prognostic unfavorable (8.63e-7)" "validated prognostic unfavorable (1.82e-5)" "unprognostic (6.49e-2)" "unprognostic (6.30e-2)" "unprognostic (1.35e-1)" "unprognostic (1.81e-1)" "potential prognostic unfavorable (5.58e-4)" "unprognostic (3.41e-3)" "unprognostic (2.38e-2)" "unprognostic (1.15e-1)" "unprognostic (4.23e-2)" "unprognostic (2.44e-2)" "unprognostic (6.13e-2)" "unprognostic (3.88e-1)" "unprognostic (1.22e-1)" "unprognostic (3.96e-2)" DEPDC4 "DEP.4, FLJ33505" ENSG00000166153 "DEP domain containing 4" Q8N2C3 12 100203669-100267079 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "testis: 2.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 38.4;Epicardial cells: 40.9;Late spermatids: 31.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" HPA039323 Uncertain Approved Microtubules NA NA "Cluster 76: Non-specific - Metabolism" "Cluster 9: Non-specific - Receptor signaling" "Cluster 63: Non-specific - Protein processing" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" Microtubules "HPA039323: " "unprognostic (6.27e-2)" "unprognostic (2.81e-1)" "unprognostic (1.24e-1)" "unprognostic (6.91e-2)" "unprognostic (1.42e-2)" "unprognostic (1.78e-1)" DEPDC5 "DEP.5, KIAA0645" ENSG00000100150 "DEP domain containing 5, GATOR1 subcomplex subunit" O75140 22 31753867-31908033 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "GTPase activation" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Astrocytes: 33.3;Bergmann glia: 30.1;Brain excitatory neurons: 39.3;Brain inhibitory neurons: 35.8;Choroid plexus epithelial cells: 82.4;Ependymal cells: 30.0;Microglia: 50.5;Oligodendrocyte progenitor cells: 34.3;Oligodendrocytes: 41.8;Other brain neurons: 23.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 34.9" "Lineage enriched" "Detected in all" 5 "granulocytes: 34.9" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054969, HPA055619" Uncertain NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 53: Neurons - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 22: Non-specific - Basic cellular functions" 15 "HPA054969: , HPA055619: " "unprognostic (2.17e-2)" "unprognostic (2.23e-1)" "unprognostic (1.21e-1)" "unprognostic (3.08e-2)" "unprognostic (3.24e-3)" "unprognostic (2.89e-2)" "unprognostic (1.67e-2)" "unprognostic (4.27e-2)" "unprognostic (3.16e-1)" "unprognostic (5.63e-2)" "potential prognostic favorable (2.22e-5)" "unprognostic (3.60e-3)" "unprognostic (6.85e-2)" "unprognostic (2.51e-1)" "unprognostic (2.21e-2)" "unprognostic (3.38e-1)" "unprognostic (2.33e-1)" "unprognostic (1.58e-2)" "unprognostic (6.65e-3)" "unprognostic (1.90e-1)" "unprognostic (3.01e-1)" "unprognostic (6.77e-2)" "unprognostic (4.96e-3)" "unprognostic (2.78e-1)" "unprognostic (3.30e-2)" "unprognostic (1.84e-2)" "unprognostic (1.46e-1)" "unprognostic (6.48e-3)" "unprognostic (1.48e-1)" "unprognostic (4.82e-3)" "unprognostic (1.34e-1)" DEPDC7 ENSG00000121690 "DEP domain containing 7" Q96QD5 11 33015876-33033582 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 27.3;kidney: 18.2;liver: 69.2;testis: 26.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 38.6;Early spermatids: 179.7;Enterocytes: 45.1;Extravillous trophoblasts: 77.2;Hepatocytes: 41.2;Late primary spermatocytes: 150.8;Oocytes: 36.8;Schwann cells: 35.0;Tuft cells: 57.6" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 8.1;committed oligodendrocyte precursor: 9.2;oligodendrocyte: 14.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 6.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Spleen - Fibroblasts_1, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA015800 Approved Nucleoplasm,Nucleoli,Cytosol Yes No "Cluster 29: Non-specific - Unknown function" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" Nucleoli "Nucleoplasm, Cytosol" "HPA015800: " "unprognostic (1.42e-1)" "unprognostic (1.32e-1)" "unprognostic (3.97e-1)" "unprognostic (6.01e-2)" "unprognostic (3.65e-1)" "unprognostic (6.53e-2)" "unprognostic (1.21e-1)" "unprognostic (2.00e-2)" "unprognostic (1.90e-1)" "potential prognostic favorable (6.13e-6)" "unprognostic (2.08e-2)" "unprognostic (2.37e-1)" "validated prognostic favorable (2.69e-4)" "validated prognostic favorable (3.35e-4)" "unprognostic (1.70e-1)" "unprognostic (3.64e-2)" "unprognostic (1.68e-2)" "unprognostic (2.87e-2)" "unprognostic (2.93e-2)" "unprognostic (2.16e-3)" "unprognostic (7.84e-3)" "unprognostic (7.84e-3)" "unprognostic (1.93e-1)" "unprognostic (2.68e-1)" "unprognostic (1.38e-1)" "unprognostic (3.78e-2)" "unprognostic (1.01e-2)" "unprognostic (1.55e-1)" DEPP1 "C10orf10, DEPP, FIG, Fseg" ENSG00000165507 "DEPP1 autophagy regulator" Q9NTK1 10 44970981-44978809 "Predicted intracellular proteins" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 858.3;breast: 687.9" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 532.6;Epididymal principal cells: 213.2;Fibroblasts: 302.9;Lymphatic endothelial cells: 181.3;Neuroendocrine cells: 166.6;Ovarian stromal cells: 242.2;Pancreatic duct cells: 170.7;Pancreatic islet cells: 283.0;Pericytes: 218.4;Syncytiotrophoblasts: 402.9;Thymic myoid cells: 312.7;Vascular endothelial cells: 299.8;Vascular smooth muscle cells: 167.5" "Cell type enriched" "Detected in many" 5 "endothelial cell: 158.4" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 277.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.0" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Kidney cancer: 53.4" "Colon - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB013687, HPA037818, HPA037819" Uncertain Supported Vesicles,Mitochondria NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 44: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 1 Mitochondria Vesicles "CAB013687: , HPA037818: , HPA037819: " "unprognostic (3.08e-2)" "unprognostic (1.17e-2)" "potential prognostic unfavorable (3.66e-4)" "unprognostic (1.17e-2)" "potential prognostic unfavorable (4.08e-4)" "unprognostic (1.40e-2)" "unprognostic (7.12e-3)" "unprognostic (4.51e-3)" "unprognostic (2.06e-1)" "unprognostic (9.98e-2)" "unprognostic (2.61e-1)" "unprognostic (1.09e-2)" "unprognostic (1.61e-1)" "unprognostic (5.27e-2)" "unprognostic (5.48e-3)" "unprognostic (6.20e-2)" "unprognostic (2.34e-2)" "unprognostic (5.98e-2)" "unprognostic (8.46e-2)" "unprognostic (1.97e-1)" "unprognostic (1.68e-1)" "unprognostic (4.99e-2)" "unprognostic (2.16e-2)" "unprognostic (1.52e-3)" "unprognostic (1.59e-1)" "potential prognostic unfavorable (9.39e-4)" "unprognostic (2.69e-1)" "unprognostic (3.11e-1)" "unprognostic (1.95e-1)" DEPTOR "DEP.6, DEPDC6, FLJ12428" ENSG00000155792 "DEP domain containing MTOR interacting protein" Q8TB45 8 119873717-120050918 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 148.1;tongue: 114.2" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 318.2;Distal convoluted tubule cells: 416.6;Lacrimal acinar cells: 318.9;Loop of henle epithelial cells: 578.3;Myonuclei: 834.3;Pituicytes/FSCs: 448.9;Salivary acinar cells: 320.9" "Cell type enhanced" "Detected in all" "mammillary body: 269.0;oligodendrocyte: 242.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 11 "myeloid DC: 20.3" "Lineage enriched" "Detected in many" 11 "dendritic cells: 20.3" "Cancer enriched" "Detected in many" 4 "Myeloma: 105.1" "Adrenal gland - Adrenal cortex cells, Breast - Breast myoepithelial cells, Spleen - Fibroblasts_2, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020841, HPA023938, HPA023945, HPA024011" Enhanced Approved "Nucleoplasm,Nuclear bodies,Mitochondria" No No "Cluster 2: Dendritic cells - Unknown function" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 14 Mitochondria "Nucleoplasm, Nuclear bodies" "CAB020841: , HPA023938: , HPA023945: , HPA024011: " "unprognostic (1.49e-1)" "unprognostic (1.30e-1)" "unprognostic (5.58e-2)" "unprognostic (2.61e-2)" "unprognostic (2.11e-2)" "unprognostic (1.19e-1)" "unprognostic (1.96e-3)" "unprognostic (2.89e-1)" "unprognostic (1.28e-2)" "potential prognostic favorable (6.75e-8)" "unprognostic (3.68e-3)" "unprognostic (7.37e-2)" "unprognostic (2.54e-1)" "unprognostic (1.93e-1)" "unprognostic (2.35e-2)" "unprognostic (3.95e-2)" "unprognostic (3.16e-2)" "unprognostic (1.49e-1)" "unprognostic (6.09e-2)" "unprognostic (1.56e-1)" "unprognostic (1.82e-2)" "unprognostic (2.16e-2)" "unprognostic (4.91e-3)" "unprognostic (1.62e-1)" "unprognostic (2.20e-2)" "unprognostic (3.23e-1)" "unprognostic (7.65e-2)" "unprognostic (2.27e-1)" "unprognostic (3.40e-2)" "unprognostic (3.24e-2)" DERA "CGI-26, DEOC" ENSG00000023697 "Deoxyribose-phosphate aldolase" Q9Y315 12 15911302-16037381 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 97.7" "Cell type enhanced" "Detected in all" "Platelets: 463.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055897 Supported Nucleoplasm NA NA 290000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 76: Non-specific - Metabolism" "Cluster 8: Immune cells - Immune response" "Cluster 38: Non-specific - Transcription" "Cluster 47: Platelets - Hemostasis" 6 Nucleoplasm "HPA055897: " "unprognostic (2.55e-3)" "unprognostic (3.69e-2)" "unprognostic (1.36e-1)" "unprognostic (9.76e-2)" "unprognostic (2.56e-2)" "unprognostic (3.30e-1)" "unprognostic (2.42e-1)" "potential prognostic favorable (7.08e-4)" "unprognostic (1.35e-1)" "unprognostic (6.29e-3)" "potential prognostic favorable (1.29e-7)" "unprognostic (1.78e-1)" "unprognostic (1.67e-1)" "unprognostic (2.71e-1)" "potential prognostic unfavorable (6.71e-5)" "potential prognostic unfavorable (1.55e-4)" "unprognostic (2.27e-1)" "unprognostic (1.30e-2)" "unprognostic (3.84e-3)" "unprognostic (8.61e-2)" "unprognostic (1.55e-1)" "validated prognostic unfavorable (2.67e-4)" "validated prognostic unfavorable (8.21e-4)" "unprognostic (1.39e-1)" "unprognostic (7.26e-2)" "unprognostic (4.29e-2)" "unprognostic (7.61e-2)" "unprognostic (1.35e-1)" "unprognostic (1.13e-1)" "unprognostic (2.59e-3)" "unprognostic (8.22e-3)" DERL1 "DER-1, DER1, derlin-1, FLJ13784, MGC3067, PRO2577" ENSG00000136986 "Derlin 1" Q9BUN8 8 123013170-123042302 "Plasma proteins, Predicted membrane proteins, Transporters" "Host-virus interaction, Protein transport, Transport, Unfolded protein response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 255.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016562, CAB037269" Supported Supported "Endoplasmic reticulum" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 40: Non-specific - Unknown function" "Cluster 44: Plasma cells - Antibody production & secretion" 73 "Endoplasmic reticulum" "CAB037269: , HPA016562: " "unprognostic (3.85e-3)" "potential prognostic unfavorable (3.03e-4)" "unprognostic (1.29e-1)" "potential prognostic unfavorable (5.69e-4)" "unprognostic (1.35e-1)" "unprognostic (1.51e-2)" "unprognostic (1.83e-2)" "unprognostic (7.43e-2)" "unprognostic (3.33e-3)" "potential prognostic unfavorable (3.02e-5)" "unprognostic (1.01e-3)" "unprognostic (2.43e-1)" "unprognostic (2.07e-2)" "unprognostic (1.52e-2)" "unprognostic (6.24e-2)" "potential prognostic unfavorable (9.37e-4)" "unprognostic (3.65e-2)" "unprognostic (1.09e-1)" "unprognostic (3.51e-1)" "unprognostic (1.21e-1)" "unprognostic (1.63e-1)" "unprognostic (4.70e-3)" "unprognostic (8.01e-3)" "unprognostic (8.06e-2)" "unprognostic (2.22e-1)" "unprognostic (9.28e-3)" "unprognostic (1.41e-2)" "unprognostic (1.90e-2)" "unprognostic (8.11e-2)" "unprognostic (3.52e-1)" "unprognostic (8.41e-2)" DERL2 "CGI-101, derlin-2, F-LAN-1, F-LANa, FLANa" ENSG00000072849 "Derlin 2" Q9GZP9 17 5471254-5486811 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction, Unfolded protein response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 217.2;Late primary spermatocytes: 305.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037287, HPA048957, HPA056551" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 70: Non-specific - Protein processing" "Cluster 55: Non-specific - Transcription" "Cluster 42: Non-specific - Unknown function" "Cluster 8: Non-specific - Secretory pathway" 62 "Endoplasmic reticulum" "CAB037287: , HPA048957: , HPA056551: " "unprognostic (6.00e-2)" "unprognostic (1.20e-3)" "unprognostic (2.87e-2)" "unprognostic (1.31e-2)" "unprognostic (6.15e-2)" "unprognostic (2.49e-2)" "unprognostic (2.37e-2)" "unprognostic (3.93e-2)" "unprognostic (6.28e-2)" "unprognostic (4.52e-3)" "potential prognostic favorable (2.29e-5)" "unprognostic (3.74e-1)" "unprognostic (5.27e-2)" "unprognostic (1.74e-1)" "unprognostic (2.18e-1)" "unprognostic (1.10e-2)" "unprognostic (2.28e-1)" "unprognostic (3.39e-2)" "unprognostic (2.92e-2)" "unprognostic (2.15e-2)" "unprognostic (2.35e-1)" "unprognostic (4.36e-1)" "potential prognostic unfavorable (1.34e-4)" "unprognostic (2.89e-2)" "unprognostic (1.40e-1)" "unprognostic (6.64e-2)" "unprognostic (2.46e-1)" "unprognostic (2.25e-1)" "unprognostic (2.50e-1)" "unprognostic (1.15e-2)" "unprognostic (8.49e-2)" DERL3 "C22orf14, derlin-3, FLJ43842, IZP6, MGC71803" ENSG00000099958 "Derlin 3" Q96Q80 22 23834503-23839128 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 41.2;pancreas: 41.6;salivary gland: 34.3" "Cell type enriched" "Detected in some" 4 "Plasma cells: 800.5" "Cell type enhanced" "Detected in many" "ependymal cell: 14.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 14 "plasmacytoid DC: 187.8" "Lineage enriched" "Detected in many" 14 "dendritic cells: 187.8" "Cancer enriched" "Detected in many" 7 "Myeloma: 39.7" "Adipose visceral - Plasma cells, Breast - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB037234, HPA049306" Approved Uncertain Vesicles NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 60: Stomach - Digestion" "Cluster 46: Brainstem - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 67: Plasma cells - Plasma cell differentiation" 14 Vesicles "CAB037234: , HPA049306: " "unprognostic (2.36e-1)" "unprognostic (6.41e-2)" "unprognostic (2.29e-2)" "potential prognostic favorable (5.85e-6)" "unprognostic (2.90e-1)" "unprognostic (1.04e-1)" "unprognostic (8.67e-3)" "unprognostic (4.50e-2)" "unprognostic (3.62e-3)" "potential prognostic unfavorable (1.15e-4)" "unprognostic (3.98e-2)" "unprognostic (3.61e-2)" "unprognostic (2.48e-1)" "unprognostic (1.71e-1)" "unprognostic (9.95e-3)" "unprognostic (3.30e-1)" "unprognostic (2.07e-1)" "unprognostic (2.75e-1)" "unprognostic (1.78e-1)" "unprognostic (3.35e-1)" "unprognostic (2.59e-2)" "potential prognostic favorable (3.85e-5)" "unprognostic (8.98e-2)" "unprognostic (2.12e-1)" "unprognostic (3.37e-3)" "unprognostic (1.28e-1)" "unprognostic (1.51e-1)" "unprognostic (2.43e-2)" "unprognostic (3.16e-2)" "unprognostic (4.16e-1)" DERPC ENSG00000286140 "DERPC proline and glycine rich nuclear protein" P0CG12 16 69118010-69132588 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA051872, HPA065522" Approved Enhanced Nucleoplasm NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 22: Epididymis - Mixed function" "Cluster 7: Non-specific - Ribosome" "Cluster 68: Non-specific - Cell cycle regulation" Nucleoplasm "HPA051872: , HPA065522: " "unprognostic (1.28e-2)" "potential prognostic unfavorable (3.14e-4)" "unprognostic (1.31e-1)" "unprognostic (8.68e-2)" "unprognostic (2.74e-1)" "unprognostic (2.99e-1)" "unprognostic (3.60e-3)" "unprognostic (9.66e-2)" "unprognostic (6.34e-2)" "unprognostic (1.60e-2)" "potential prognostic favorable (8.92e-4)" "unprognostic (1.08e-3)" "unprognostic (1.42e-2)" "unprognostic (3.22e-3)" "unprognostic (1.70e-1)" "unprognostic (1.05e-1)" "unprognostic (2.15e-1)" "unprognostic (8.63e-2)" "unprognostic (9.89e-2)" "unprognostic (2.79e-1)" "unprognostic (1.15e-1)" "unprognostic (2.63e-1)" "unprognostic (6.22e-3)" "unprognostic (2.65e-1)" "unprognostic (2.09e-1)" "unprognostic (1.16e-1)" DES "CMD1I, CSM1, CSM2" ENSG00000175084 Desmin P17661 2 219418377-219426735 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Muscle protein" "Cancer-related genes, Cardiomyopathy, Desmin-related myopathy, Disease variant, Limb-girdle muscular dystrophy, Myofibrillar myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 5337.8;intestine: 4319.2;skeletal muscle: 10128.8" "Group enriched" "Detected in many" 7 "Smooth muscle cells: 7110.7;Thymic myoid cells: 2325.0" "Cell type enriched" "Detected in single" 195 "vascular associated smooth muscle cell: 60.0" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 805.1;Stomach Adenocarcinoma (TCGA): 661.4" "Region enhanced" "Detected in many" "cerebral cortex: 12.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 62 "Sarcoma: 73.7" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Adrenal gland - Smooth muscle cells, Colon - Smooth muscle cells, Heart muscle - Cardiomyocytes, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Skin - Smooth muscle cells, Spleen - Smooth muscle cells, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 5 "midbrain: 40.3" "CAB000034, HPA018803" Enhanced Supported "Intermediate filaments" NA NA 2300000 "Cluster 25: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 62: Smooth muscle cells - Muscle contraction" 79 "Intermediate filaments" "CAB000034: , HPA018803: " "potential prognostic favorable (9.68e-4)" "unprognostic (2.72e-1)" "unprognostic (2.29e-2)" "unprognostic (6.00e-3)" "unprognostic (1.37e-1)" "unprognostic (1.35e-1)" "unprognostic (2.11e-2)" "potential prognostic unfavorable (5.56e-6)" "unprognostic (4.24e-3)" "unprognostic (3.79e-2)" "unprognostic (4.42e-1)" "unprognostic (1.85e-2)" "potential prognostic unfavorable (8.04e-5)" "unprognostic (1.76e-1)" "unprognostic (3.18e-1)" "unprognostic (4.11e-3)" "unprognostic (5.68e-2)" "potential prognostic unfavorable (6.81e-4)" "unprognostic (1.02e-1)" "unprognostic (9.56e-2)" "unprognostic (1.80e-1)" "unprognostic (1.37e-1)" "unprognostic (6.25e-2)" "unprognostic (3.62e-2)" "unprognostic (9.99e-3)" "unprognostic (4.42e-2)" "unprognostic (3.63e-1)" "unprognostic (3.16e-2)" "unprognostic (2.42e-1)" "unprognostic (1.12e-1)" "unprognostic (1.64e-1)" DESI1 "D15Wsu75e, DESI-1, FAM152B, POST, PPPDE2" ENSG00000100418 "Desumoylating isopeptidase 1" Q6ICB0 22 41598028-41621043 "Predicted intracellular proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 935.5;Esophageal apical cells: 584.8;Esophageal suprabasal cells: 225.6;Late primary spermatocytes: 444.3;Late spermatids: 809.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053415 Approved Approved "Cytokinetic bridge,Cytosol" Yes No "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 76: Non-specific - Metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 29 Cytosol "Cytokinetic bridge" "HPA053415: " "unprognostic (2.34e-1)" "unprognostic (6.82e-2)" "unprognostic (7.29e-3)" "unprognostic (1.39e-1)" "unprognostic (8.35e-2)" "unprognostic (3.39e-2)" "unprognostic (3.26e-1)" "unprognostic (2.13e-3)" "unprognostic (3.72e-2)" "potential prognostic unfavorable (3.75e-4)" "unprognostic (1.00e-1)" "unprognostic (2.56e-1)" "unprognostic (7.69e-3)" "unprognostic (5.09e-3)" "unprognostic (1.09e-1)" "unprognostic (1.53e-1)" "unprognostic (3.34e-2)" "unprognostic (2.16e-1)" "unprognostic (2.26e-1)" "unprognostic (3.70e-2)" "unprognostic (2.59e-2)" "unprognostic (1.80e-2)" "unprognostic (5.16e-3)" "unprognostic (1.21e-1)" "unprognostic (7.11e-2)" "unprognostic (9.13e-2)" "unprognostic (1.69e-1)" "unprognostic (1.15e-2)" "unprognostic (2.41e-1)" DESI2 "C1orf121, CGI-146, DESI-2, FAM152A, FLJ21998, PNAS-4, PPPDE1" ENSG00000121644 "Desumoylating isopeptidase 2" Q9BSY9 1 244653103-244709033 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 226.6;Late primary spermatocytes: 294.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049950 Approved Vesicles NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 54: Immune cells - T cell receptor" "Cluster 45: Non-specific - Nuclear processes" "Cluster 81: Alveolar cells - Lung function" 10 Vesicles "HPA049950: " "unprognostic (6.33e-2)" "unprognostic (2.06e-2)" "unprognostic (1.89e-2)" "unprognostic (6.78e-2)" "unprognostic (4.40e-2)" "unprognostic (1.66e-1)" "unprognostic (5.44e-2)" "unprognostic (6.42e-2)" "unprognostic (1.42e-1)" "unprognostic (6.06e-3)" "unprognostic (2.89e-1)" "unprognostic (4.55e-2)" "unprognostic (1.08e-3)" "unprognostic (6.86e-2)" "unprognostic (2.25e-2)" "unprognostic (2.93e-1)" "unprognostic (1.33e-1)" "unprognostic (3.33e-1)" "unprognostic (1.15e-1)" "unprognostic (1.61e-3)" "unprognostic (1.65e-1)" "unprognostic (1.55e-1)" "unprognostic (1.20e-3)" "unprognostic (1.25e-1)" "unprognostic (2.78e-2)" "unprognostic (1.34e-1)" "unprognostic (1.67e-1)" "unprognostic (2.55e-2)" "unprognostic (1.00e-1)" DET1 FLJ10103 ENSG00000140543 "DET1 partner of COP1 E3 ubiquitin ligase" Q7L5Y6 15 88494440-88546681 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 10.2;Bergmann glia: 13.2;Cardiomyocytes: 14.0;Choroid plexus epithelial cells: 16.6;Distal convoluted tubule cells: 28.7;Ependymal cells: 13.7;Loop of henle epithelial cells: 30.5;Oligodendrocyte progenitor cells: 10.9;Oligodendrocytes: 11.6;Papillary tip epithelial cells: 24.4;Podocytes: 32.8;Proximal tubule cells: 20.1;Renal collecting duct intercalated cells: 29.1;Renal collecting duct principal cells: 26.7;Renal connecting tubule cells: 22.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048873 Uncertain Approved "Nucleoplasm,Microtubules,Cytokinetic bridge" Yes No "Cluster 29: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 105: Non-specific - Mixed function" 38 Microtubules "Nucleoplasm, Cytokinetic bridge" "HPA048873: " "unprognostic (1.20e-2)" "unprognostic (1.70e-1)" "unprognostic (1.16e-1)" "unprognostic (3.73e-2)" "unprognostic (2.96e-1)" "unprognostic (6.61e-2)" "unprognostic (1.61e-1)" "unprognostic (1.37e-3)" "unprognostic (9.95e-2)" "unprognostic (9.10e-2)" "validated prognostic favorable (1.90e-10)" "validated prognostic favorable (3.60e-4)" "unprognostic (6.27e-2)" "unprognostic (3.60e-3)" "unprognostic (4.79e-2)" "unprognostic (1.55e-1)" "unprognostic (1.69e-1)" "unprognostic (2.05e-1)" "unprognostic (9.65e-2)" "unprognostic (2.45e-1)" "unprognostic (2.51e-2)" "unprognostic (1.08e-1)" "unprognostic (3.25e-1)" "unprognostic (2.53e-1)" "unprognostic (5.11e-2)" "unprognostic (1.17e-1)" "unprognostic (1.64e-1)" "unprognostic (2.71e-2)" "unprognostic (1.81e-1)" "unprognostic (5.63e-2)" "unprognostic (7.23e-2)" DEUP1 "CCDC67, FLJ25393" ENSG00000165325 "Deuterosome assembly protein 1" Q05D60 11 93329971-93438487 "Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "fallopian tube: 4.5;testis: 15.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 80.4;Early spermatids: 234.6;Fallopian tube ciliated cells: 63.6;Late primary spermatocytes: 337.8;Late spermatids: 244.1;Respiratory ciliated cells: 61.9;Respiratory deuterosomal cells: 115.1" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 30.5;ependymal cell: 48.9" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Adrenocortical cancer: 1.2" "Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" 40 "unprognostic (9.13e-2)" "unprognostic (1.49e-1)" "unprognostic (1.67e-1)" "unprognostic (2.48e-2)" "unprognostic (2.83e-1)" DEXI MYLE ENSG00000182108 "Dexi homolog" O95424 16 10928891-10942468 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "cDC: 119.0;Hepatocytes: 126.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041511 Approved Approved "Nuclear speckles,Cytosol" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 82: Dendritic cells - Antigen presentation" 8 "Nuclear speckles" Cytosol "HPA041511: " "potential prognostic unfavorable (8.42e-4)" "unprognostic (1.45e-1)" "unprognostic (2.18e-2)" "unprognostic (2.42e-1)" "unprognostic (2.68e-1)" "unprognostic (9.81e-2)" "unprognostic (3.70e-2)" "unprognostic (1.14e-1)" "unprognostic (5.10e-2)" "unprognostic (2.74e-2)" "unprognostic (6.08e-3)" "unprognostic (2.72e-2)" "unprognostic (1.64e-1)" "unprognostic (1.58e-3)" "unprognostic (1.70e-2)" "unprognostic (1.79e-2)" "unprognostic (4.19e-1)" "unprognostic (1.43e-1)" "unprognostic (6.21e-2)" "potential prognostic unfavorable (8.63e-4)" "unprognostic (2.61e-2)" "unprognostic (1.48e-3)" "unprognostic (1.58e-1)" "unprognostic (4.10e-2)" "unprognostic (1.19e-2)" "unprognostic (1.25e-1)" "unprognostic (1.04e-1)" "potential prognostic unfavorable (4.75e-4)" "unprognostic (1.01e-1)" "unprognostic (3.32e-1)" "unprognostic (6.69e-2)" DFFA "DFF-45, DFF1, DFF45, ICAD" ENSG00000160049 "DNA fragmentation factor subunit alpha" O00273 1 10456522-10472529 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 117.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002679, HPA018859, HPA019938, HPA025230" Supported Approved "Plasma membrane,Cytosol" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 16 "Plasma membrane, Cytosol" "CAB002679: , HPA018859: , HPA019938: , HPA025230: " "unprognostic (2.94e-1)" "unprognostic (1.23e-1)" "unprognostic (8.25e-2)" "unprognostic (5.62e-3)" "unprognostic (8.47e-3)" "unprognostic (1.28e-1)" "unprognostic (3.60e-1)" "unprognostic (6.03e-2)" "unprognostic (2.95e-1)" "unprognostic (2.85e-3)" "validated prognostic favorable (1.71e-6)" "validated prognostic favorable (3.06e-4)" "unprognostic (7.96e-2)" "validated prognostic unfavorable (4.76e-5)" "validated prognostic unfavorable (6.37e-5)" "unprognostic (2.12e-1)" "unprognostic (1.97e-2)" "unprognostic (3.23e-2)" "unprognostic (6.47e-2)" "unprognostic (1.17e-2)" "unprognostic (1.66e-1)" "unprognostic (2.81e-2)" "unprognostic (1.73e-1)" "unprognostic (2.22e-1)" "unprognostic (1.59e-1)" "unprognostic (5.13e-3)" "unprognostic (1.48e-1)" "unprognostic (7.94e-3)" "unprognostic (1.54e-1)" "unprognostic (1.03e-1)" "unprognostic (3.28e-1)" DFFB "CAD, CPAN, DFF-40, DFF40" ENSG00000169598 "DNA fragmentation factor subunit beta" O76075 1 3857267-3885429 "Predicted intracellular proteins" Apoptosis "Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 82.8;Extravillous trophoblasts: 43.1;Megakaryocyte-Erythroid progenitors: 80.4;Thymocytes: 102.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004328, HPA052904" Approved Supported Nucleoplasm,Nucleoli NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 60: Stomach - Digestion" "Cluster 11: White matter - Signal transduction" "Cluster 37: Non-specific - mRNA processing" "Cluster 79: Photoreceptor cells - Phototransduction" 5 Nucleoli Nucleoplasm "CAB004328: , HPA052904: " "unprognostic (1.87e-2)" "unprognostic (3.57e-1)" "unprognostic (1.73e-1)" "unprognostic (8.90e-2)" "unprognostic (2.77e-2)" "unprognostic (1.56e-1)" "unprognostic (3.05e-2)" "unprognostic (1.38e-3)" "unprognostic (5.13e-2)" "unprognostic (3.00e-1)" "unprognostic (2.47e-1)" "unprognostic (1.24e-1)" "unprognostic (1.65e-1)" "unprognostic (1.71e-1)" "unprognostic (1.18e-1)" "unprognostic (5.52e-2)" "unprognostic (3.73e-1)" "unprognostic (6.25e-2)" "unprognostic (3.92e-2)" "unprognostic (5.13e-2)" "unprognostic (1.66e-1)" "unprognostic (8.02e-2)" "unprognostic (1.44e-1)" "unprognostic (5.80e-2)" DGAT1 "ARGP1, DGAT" ENSG00000185000 "Diacylglycerol O-acyltransferase 1" O75907 8 144314584-144326910 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid metabolism" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 41.8" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 20.4;Astrocytes: 19.0;Bergmann glia: 14.3;Brain excitatory neurons: 15.2;Brain inhibitory neurons: 14.9;Choroid plexus epithelial cells: 14.0;Enterocytes: 21.0;Oligodendrocyte progenitor cells: 23.7;Oligodendrocytes: 13.2;Other brain neurons: 11.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB032853 Enhanced Approved "Nucleoli,Nucleoli rim,Endoplasmic reticulum" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 15: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 102: Non-specific - Mixed function" 6 "Endoplasmic reticulum" "Nucleoli, Nucleoli rim" "CAB032853: " "unprognostic (5.29e-2)" "unprognostic (9.75e-3)" "unprognostic (1.91e-1)" "unprognostic (2.65e-2)" "unprognostic (2.87e-2)" "unprognostic (1.99e-1)" "unprognostic (6.02e-2)" "unprognostic (1.11e-1)" "unprognostic (9.95e-2)" "unprognostic (1.76e-2)" "unprognostic (3.06e-3)" "unprognostic (3.06e-1)" "unprognostic (1.06e-1)" "unprognostic (1.62e-1)" "unprognostic (8.10e-2)" "unprognostic (5.61e-2)" "unprognostic (1.07e-1)" "unprognostic (2.76e-2)" "unprognostic (3.34e-1)" "unprognostic (2.67e-1)" "unprognostic (1.20e-1)" "unprognostic (2.13e-1)" "unprognostic (9.71e-3)" "unprognostic (2.22e-1)" "unprognostic (8.83e-2)" "unprognostic (2.93e-1)" "unprognostic (5.87e-2)" "unprognostic (3.51e-2)" "unprognostic (3.40e-1)" "unprognostic (5.51e-2)" "unprognostic (4.10e-1)" DGAT2 ENSG00000062282 "Diacylglycerol O-acyltransferase 2" Q96PD7 11 75759512-75801535 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins" "Glycerol metabolism, Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "adipose tissue: 447.0;breast: 135.2;liver: 309.8;skin 1: 147.4" "Cell type enhanced" "Detected in many" "Adipocytes: 313.4;Early primary spermatocytes: 66.6;Early spermatids: 355.5;Esophageal apical cells: 187.1;Hepatocytes: 144.6;Late primary spermatocytes: 134.4;Late spermatids: 110.7;Neutrophils: 399.2" "Cell type enhanced" "Detected in many" "medium spiny neuron: 16.7" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 96.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "eosinophil: 138.1;neutrophil: 350.5" "Lineage enriched" "Detected in many" 16 "granulocytes: 350.5" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Lung - Neutrophils_2, Skin - Keratinocyte (granular), Spleen - Neutrophils_2, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "basal ganglia: 30.0" HPA013351 Approved Vesicles,Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 33: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 29: Neutrophils - Innate immune cellular maintenance" "Vesicles, Cytosol" "HPA013351: " "unprognostic (1.85e-2)" "unprognostic (4.05e-2)" "unprognostic (1.24e-1)" "unprognostic (2.44e-2)" "unprognostic (6.67e-2)" "unprognostic (4.34e-1)" "unprognostic (1.60e-1)" "unprognostic (3.47e-1)" "unprognostic (6.98e-2)" "unprognostic (2.95e-1)" "unprognostic (1.38e-2)" "unprognostic (6.16e-2)" "potential prognostic unfavorable (9.18e-4)" "unprognostic (7.96e-3)" "unprognostic (3.48e-3)" "unprognostic (2.47e-1)" "unprognostic (2.87e-2)" "unprognostic (5.92e-3)" "unprognostic (1.37e-1)" "unprognostic (3.39e-2)" "unprognostic (2.78e-1)" "unprognostic (2.15e-1)" "potential prognostic favorable (3.80e-4)" "unprognostic (2.98e-1)" "unprognostic (1.17e-2)" "unprognostic (2.64e-1)" "unprognostic (6.25e-2)" "unprognostic (1.35e-1)" "unprognostic (1.94e-1)" "unprognostic (2.81e-2)" "unprognostic (1.55e-1)" DGAT2L6 "DC3, FLJ25989" ENSG00000184210 "Diacylglycerol O-acyltransferase 2 like 6" Q6ZPD8 X 70177483-70205704 "Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 40 "breast: 1.9;skin 1: 6.1" "Cell type enhanced" "Detected in some" "Adipocytes: 7.8;Bergmann glia: 2.8;Cardiomyocytes: 4.1;Epicardial cells: 9.1;Fibro-adipogenic progenitors: 6.2;Hematopoietic stem cells: 3.9;Mesothelial cells: 4.1;Myonuclei: 8.2;Retinal amacrine cells: 3.2;Schwann cells: 4.2" "Cell type enhanced" "Detected in some" "Bergmann glia: 4.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Sebaceous gland cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 47: Leukemia - Hemostasis" "Cluster 89: Adipocytes - Lipid metabolism" 37 DGCR2 "DGS-C, IDD, KIAA0163, LAN, SEZ-12" ENSG00000070413 "DiGeorge syndrome critical region gene 2" P98153 22 19036282-19122454 "Human disease related genes, Predicted membrane proteins" "Cell adhesion" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 231.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000873 Uncertain NA NA 74000 "Cluster 21: Neutrophils - Unknown function" "Cluster 2: Non-specific - Mixed function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 24: Neutrophils - Innate immunity signal integration" 27 "HPA000873: " "unprognostic (3.94e-2)" "unprognostic (2.03e-1)" "unprognostic (1.34e-1)" "unprognostic (2.05e-2)" "unprognostic (1.93e-2)" "unprognostic (2.23e-1)" "unprognostic (5.81e-2)" "unprognostic (7.50e-2)" "unprognostic (7.45e-2)" "unprognostic (1.73e-1)" "potential prognostic favorable (1.79e-5)" "unprognostic (1.28e-3)" "unprognostic (1.63e-2)" "unprognostic (1.03e-2)" "unprognostic (2.50e-2)" "unprognostic (1.70e-1)" "unprognostic (7.47e-2)" "unprognostic (7.54e-3)" "unprognostic (1.16e-1)" "unprognostic (7.61e-2)" "unprognostic (5.51e-2)" "unprognostic (3.50e-2)" "unprognostic (3.70e-1)" "unprognostic (2.63e-2)" "unprognostic (9.59e-2)" "unprognostic (8.65e-2)" "unprognostic (1.13e-1)" "unprognostic (1.14e-1)" "unprognostic (3.08e-1)" "unprognostic (1.08e-1)" "unprognostic (1.24e-1)" DGCR6 ENSG00000183628 "DiGeorge syndrome critical region gene 6" Q14129 22 18906028-18914238 "Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 196.5" "Cell type enriched" "Detected in some" 7 "Late spermatids: 9.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 39.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 10.5" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "thyroid cancer: 13.0" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Pituitary gland - Gonadotropes, Testis - Late spermatids" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 66: Non-specific - Mitochondria" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 6 "unprognostic (1.64e-1)" "unprognostic (1.61e-1)" "unprognostic (9.63e-2)" "unprognostic (1.87e-1)" "unprognostic (1.72e-1)" "unprognostic (8.63e-2)" "unprognostic (2.76e-2)" "unprognostic (4.75e-2)" "unprognostic (1.96e-1)" "unprognostic (4.26e-2)" "unprognostic (4.12e-2)" "unprognostic (1.62e-2)" "unprognostic (1.57e-2)" "unprognostic (5.35e-3)" "unprognostic (8.69e-2)" "unprognostic (6.75e-2)" "unprognostic (8.94e-2)" "unprognostic (4.87e-3)" "unprognostic (1.63e-1)" "unprognostic (3.25e-3)" "unprognostic (2.08e-1)" "potential prognostic favorable (1.05e-4)" "unprognostic (2.62e-1)" "unprognostic (2.25e-1)" "unprognostic (5.56e-2)" "unprognostic (1.36e-2)" DGCR6L FLJ10666 ENSG00000128185 "DiGeorge syndrome critical region gene 6 like" Q9BY27 22 20314238-20320080 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 8 "Late spermatids: 5042.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 14 "unprognostic (2.39e-2)" "unprognostic (1.52e-1)" "unprognostic (4.07e-1)" "potential prognostic favorable (3.41e-4)" "unprognostic (1.26e-1)" "unprognostic (2.69e-2)" "unprognostic (4.01e-2)" "unprognostic (6.14e-2)" "unprognostic (1.48e-1)" "unprognostic (6.75e-2)" "unprognostic (1.74e-2)" "unprognostic (3.05e-2)" "unprognostic (1.68e-3)" "unprognostic (1.48e-1)" "unprognostic (5.94e-2)" "unprognostic (8.19e-3)" "unprognostic (2.10e-1)" "unprognostic (6.51e-2)" "unprognostic (1.81e-1)" "unprognostic (3.86e-2)" "unprognostic (2.45e-1)" "unprognostic (1.29e-2)" "unprognostic (1.82e-1)" "unprognostic (2.92e-3)" "unprognostic (2.10e-1)" "unprognostic (1.58e-1)" "unprognostic (4.29e-2)" "unprognostic (1.01e-1)" "unprognostic (1.37e-1)" "unprognostic (4.35e-1)" "unprognostic (2.46e-1)" DGCR8 "C22orf12, DGCRK6, Gy1, pasha" ENSG00000128191 "DGCR8 microprocessor complex subunit" Q8WYQ5 22 20080221-20111877 "Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 101.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA076916, HPA079351" Approved Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 61: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 66: Non-specific - Mitochondria" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 19 "Nucleoplasm, Nuclear bodies" "HPA076916: , HPA079351: " "unprognostic (2.14e-1)" "unprognostic (4.00e-2)" "unprognostic (1.54e-2)" "unprognostic (5.34e-3)" "unprognostic (2.61e-2)" "unprognostic (5.88e-2)" "unprognostic (1.40e-1)" "unprognostic (5.33e-3)" "unprognostic (4.17e-2)" "unprognostic (1.01e-1)" "potential prognostic favorable (6.56e-5)" "unprognostic (2.19e-3)" "unprognostic (1.03e-1)" "unprognostic (4.79e-3)" "unprognostic (2.66e-1)" "unprognostic (9.31e-2)" "unprognostic (9.87e-3)" "unprognostic (7.91e-2)" "unprognostic (7.58e-3)" "unprognostic (9.56e-2)" "unprognostic (4.45e-3)" "unprognostic (7.12e-2)" "unprognostic (4.70e-3)" "unprognostic (4.96e-1)" "unprognostic (6.83e-2)" "unprognostic (2.71e-1)" "unprognostic (6.63e-3)" "unprognostic (8.61e-2)" "unprognostic (2.65e-1)" "unprognostic (3.72e-3)" "unprognostic (8.76e-2)" DGKA "DAGK, DAGK1, DGK-alpha" ENSG00000065357 "Diacylglycerol kinase alpha" P23743 12 55927319-55954027 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 184.5" "Cell type enhanced" "Detected in many" "Enterocytes: 96.8;Esophageal apical cells: 200.1;Ocular epithelial cells: 87.6;Prostatic hillock cells: 84.8;Thymocytes: 75.4" "Cell type enhanced" "Detected in all" "leukocyte: 68.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Lineage enriched" "Detected in all" 4 "T-cells: 87.0" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Skin - Keratinocyte (other), Spleen - B-cells (Spleen), Testis - Early spermatids, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041645, HPA045462" Approved Approved Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 34: Non-specific - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" 1 Vesicles "Nucleoplasm, Mitochondria" "HPA041645: , HPA045462: " "unprognostic (3.26e-1)" "unprognostic (9.84e-3)" "potential prognostic favorable (1.00e-4)" "unprognostic (2.09e-1)" "unprognostic (1.77e-1)" "unprognostic (1.06e-2)" "unprognostic (2.16e-1)" "unprognostic (2.82e-3)" "unprognostic (1.45e-1)" "unprognostic (3.01e-1)" "unprognostic (3.65e-2)" "unprognostic (1.16e-1)" "unprognostic (1.25e-1)" "unprognostic (6.04e-2)" "unprognostic (6.41e-2)" "unprognostic (8.22e-3)" "unprognostic (1.21e-1)" "unprognostic (2.64e-3)" "unprognostic (4.49e-3)" "unprognostic (3.90e-2)" "unprognostic (2.71e-2)" "unprognostic (1.59e-2)" "unprognostic (1.30e-2)" "unprognostic (9.58e-2)" "unprognostic (1.02e-1)" "unprognostic (2.96e-1)" "unprognostic (5.76e-2)" "unprognostic (1.14e-1)" "unprognostic (7.79e-2)" "unprognostic (1.45e-1)" "unprognostic (5.24e-2)" DGKB "DAGK2, DGK, DGK-BETA, KIAA0718" ENSG00000136267 "Diacylglycerol kinase beta" Q9Y6T7 7 14145049-14974777 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 18.6" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 755.2;Brain excitatory neurons: 803.1;Brain inhibitory neurons: 1602.4;Corticotrophs: 1419.2;Granulosa cells: 357.6;Lactotrophs: 262.2;Oligodendrocyte progenitor cells: 309.9;Other brain neurons: 655.1;Retinal bipolar cells: 778.4;Vascular smooth muscle cells: 285.7" "Cell type enhanced" "Detected in all" "mammillary body: 4039.7;medium spiny neuron: 3076.0" "Cancer enriched" "Detected in single" 10 "Glioblastoma Multiforme (TCGA): 4.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "lung cancer: 1.8;Neuroblastoma: 4.0;Rhabdoid: 4.8" "Adrenal gland - Adrenal medulla cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "basal ganglia: 252.7" "HPA020321, HPA055763" Supported Approved "Nucleoplasm,Nuclear speckles,Plasma membrane" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 35: Neurons - Synaptic function & neurogenesis" "Plasma membrane" "Nucleoplasm, Nuclear speckles" "HPA020321: , HPA055763: " "unprognostic (6.78e-2)" "unprognostic (5.55e-2)" "unprognostic (4.91e-2)" DGKD "DGKdelta, KIAA0145" ENSG00000077044 "Diacylglycerol kinase delta" Q16760 2 233354494-233472104 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Endocytosis, Lipid metabolism, Protein transport, Transport" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 29.7;skeletal muscle: 26.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 204.1;Megakaryocytes: 160.7;Myonuclei: 199.4;Neutrophil progenitors: 158.8;Neutrophils: 228.2;Platelets: 186.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Spleen - B-cells (Spleen), Stomach - Gastric mucous cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027530, HPA049101" Approved Supported Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 24: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 6: Leukemia - Signal transduction" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 6 Cytosol "HPA027530: , HPA049101: " "unprognostic (4.00e-3)" "unprognostic (2.59e-2)" "unprognostic (1.66e-2)" "unprognostic (2.11e-1)" "unprognostic (1.68e-1)" "unprognostic (1.59e-1)" "unprognostic (4.51e-3)" "unprognostic (2.39e-3)" "unprognostic (9.78e-2)" "unprognostic (3.40e-2)" "unprognostic (1.19e-1)" "unprognostic (9.28e-2)" "unprognostic (5.45e-2)" "unprognostic (1.87e-1)" "unprognostic (2.38e-2)" "unprognostic (1.13e-1)" "unprognostic (2.48e-1)" "unprognostic (2.89e-3)" "unprognostic (6.06e-2)" "unprognostic (1.79e-1)" "unprognostic (2.09e-2)" "unprognostic (1.46e-1)" DGKE "DAGK6, DGK" ENSG00000153933 "Diacylglycerol kinase epsilon" P52429 17 56834107-56869567 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Kinase, Transferase" "Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 31.9" "Cell type enhanced" "Detected in many" "Bergmann glia: 97.9;Cone photoreceptor cells: 159.4;Lactotrophs: 118.8;Retinal bipolar cells: 243.3;Rod photoreceptor cells: 212.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Pituitary gland - Lactotropes, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017167 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 5: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 3 "Nucleoplasm, Cytosol" "HPA017167: " "unprognostic (3.46e-3)" "unprognostic (6.70e-2)" "unprognostic (1.32e-1)" "unprognostic (5.22e-2)" "unprognostic (1.96e-1)" "potential prognostic unfavorable (4.54e-5)" "unprognostic (7.45e-2)" "unprognostic (9.85e-2)" "unprognostic (3.87e-2)" "validated prognostic favorable (3.60e-4)" "validated prognostic favorable (8.82e-4)" "unprognostic (6.79e-2)" "unprognostic (6.18e-3)" "unprognostic (2.34e-1)" "unprognostic (1.48e-1)" "unprognostic (1.47e-1)" "unprognostic (1.80e-2)" "unprognostic (6.82e-2)" "unprognostic (1.20e-1)" "unprognostic (1.65e-2)" "unprognostic (4.23e-2)" "unprognostic (1.14e-1)" "unprognostic (2.18e-2)" "potential prognostic favorable (2.32e-4)" "unprognostic (2.88e-1)" "unprognostic (1.89e-1)" "unprognostic (2.52e-1)" "unprognostic (1.41e-2)" DGKG DAGK3 ENSG00000058866 "Diacylglycerol kinase gamma" P49619 3 186105668-186362234 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.7" "Cell type enhanced" "Detected in many" "Astrocytes: 529.5;Bergmann glia: 1728.3;Brain excitatory neurons: 303.4;Cardiomyocytes: 422.1;Neutrophil progenitors: 323.6;Oligodendrocyte progenitor cells: 819.5;Somatotrophs: 444.7;Vascular smooth muscle cells: 438.4" "Cell type enhanced" "Detected in all" "Bergmann glia: 1684.0" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 8.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 2.1;eosinophil: 1.2;intermediate monocyte: 1.2;myeloid DC: 1.5;neutrophil: 2.6;non-classical monocyte: 1.5" "Group enriched" "Detected in many" 7 "dendritic cells: 1.5;granulocytes: 2.6;monocytes: 2.1" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Heart muscle - Cardiomyocytes, Minor Salivary Gland - Smooth muscle cells, Pituitary gland - Corticotropes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036577 Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 27: Cerebellum - Synaptic function" "Cluster 37: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 28: Astrocytes - Homeostasis & neuron support" 4 "Vesicles, Plasma membrane" "HPA036577: " "unprognostic (1.39e-1)" "unprognostic (8.38e-3)" "unprognostic (2.15e-1)" "unprognostic (3.20e-1)" "unprognostic (3.83e-3)" "unprognostic (1.66e-1)" "unprognostic (4.77e-3)" "unprognostic (3.78e-1)" "unprognostic (3.81e-1)" "unprognostic (4.64e-2)" "unprognostic (1.60e-1)" "unprognostic (1.69e-2)" "unprognostic (2.97e-1)" "unprognostic (3.16e-1)" "unprognostic (1.10e-2)" DGKH DGKeta ENSG00000102780 "Diacylglycerol kinase eta" Q86XP1 13 42040036-42256578 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Respiratory basal cells: 584.7;Respiratory ciliated cells: 453.4;Urothelial cells: 1355.4" "Cell type enhanced" "Detected in all" "medium spiny neuron: 849.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039533, HPA040355, HPA061538" Uncertain Supported "Vesicles,Plasma membrane" NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 33: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 69: Urothelial cells - Basic cellular functions" 1 "Plasma membrane" Vesicles "HPA039533: , HPA040355: , HPA061538: " "unprognostic (7.07e-2)" "unprognostic (1.74e-1)" "unprognostic (1.19e-1)" "unprognostic (8.86e-3)" "unprognostic (7.78e-2)" "unprognostic (3.47e-2)" "unprognostic (2.65e-3)" "unprognostic (4.52e-3)" "unprognostic (3.32e-3)" "unprognostic (1.72e-2)" "potential prognostic favorable (8.65e-5)" "unprognostic (1.46e-3)" "unprognostic (3.90e-3)" "unprognostic (6.81e-2)" "potential prognostic unfavorable (2.26e-4)" "unprognostic (2.10e-1)" "unprognostic (4.82e-2)" "unprognostic (8.01e-2)" "unprognostic (1.35e-1)" "unprognostic (2.17e-3)" "unprognostic (3.68e-1)" "unprognostic (2.10e-1)" "unprognostic (1.25e-1)" "unprognostic (1.11e-1)" "unprognostic (2.60e-1)" "unprognostic (1.77e-1)" "unprognostic (5.30e-2)" "unprognostic (6.00e-2)" DGKI DGK-IOTA ENSG00000157680 "Diacylglycerol kinase iota" O75912 7 137381037-137847092 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 11.5;retina: 6.3;thyroid gland: 14.9" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 615.7;Brain inhibitory neurons: 859.8;Choroid plexus epithelial cells: 1778.5;Lactotrophs: 505.5;Respiratory ionocytes: 2131.1;Retinal amacrine cells: 584.2;Retinal bipolar cells: 933.2;Retinal horizontal cells: 1067.8;Salivary ionocytes: 4573.5;Thyrotrophs: 726.9" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Kidney Chromophobe (TCGA): 9.8;Thyroid Carcinoma (TCGA): 2.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "thyroid cancer: 9.5" "Minor Salivary Gland - Minor salivary gland ductal cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 33: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 35: Neurons - Synaptic function & neurogenesis" 1 "unprognostic (2.18e-1)" "unprognostic (1.78e-1)" "potential prognostic favorable (8.58e-5)" "unprognostic (1.47e-1)" "potential prognostic favorable (2.14e-9)" "unprognostic (2.53e-2)" "unprognostic (1.80e-1)" "unprognostic (7.42e-3)" DGKK ENSG00000274588 "Diacylglycerol kinase kappa" Q5KSL6 X 50365409-50470825 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 19 "adrenal gland: 3.2;brain: 4.3;pituitary gland: 5.7" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 74.5;Corticotrophs: 37.4;Gonadotrophs: 94.9;Other brain neurons: 13.5;Pituitary stem cells: 23.6" "Cell type enhanced" "Detected in some" "leukocyte: 10.1;medium spiny neuron: 6.6;splatter: 12.5" "Not detected" "Not detected" "Region enhanced" "Detected in many" "hypothalamus: 25.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 4.8;Neuroblastoma: 3.6" "Adrenal gland - Adrenal medulla cells, Lung - NK-cells (Lung), Pituitary gland - Corticotropes" "Region enhanced" "Detected in many" "hypothalamus: 19.8" "Low region specificity" "Detected in many" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 20: Pituitary gland - Hormone signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 18: Liver cancer - Metabolism" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" DGKQ "DAGK, DAGK4, DAGK7" ENSG00000145214 "Diacylglycerol kinase theta" P52824 4 958887-986895 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 32.1;Enterocytes: 33.3;Goblet cells: 29.7;Tuft cells: 23.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026797, CAB033835" Uncertain Approved Nucleoli NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 64: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 3 Nucleoli "CAB033835: , HPA026797: " "unprognostic (2.83e-2)" "unprognostic (3.99e-2)" "unprognostic (1.33e-1)" "unprognostic (6.70e-2)" "unprognostic (1.80e-1)" "unprognostic (3.33e-1)" "unprognostic (2.09e-1)" "unprognostic (1.99e-2)" "unprognostic (4.75e-2)" "unprognostic (1.49e-2)" "unprognostic (1.54e-1)" "unprognostic (1.17e-1)" "unprognostic (5.47e-3)" "unprognostic (2.24e-1)" "unprognostic (7.01e-2)" "unprognostic (1.48e-1)" "unprognostic (6.91e-2)" "unprognostic (3.87e-2)" "unprognostic (1.01e-1)" "unprognostic (1.93e-1)" "unprognostic (1.92e-3)" "unprognostic (3.46e-2)" "unprognostic (1.18e-1)" "unprognostic (4.30e-2)" "unprognostic (3.77e-1)" "unprognostic (6.11e-2)" "unprognostic (2.47e-1)" "potential prognostic favorable (3.48e-4)" "unprognostic (1.78e-1)" "potential prognostic unfavorable (4.86e-4)" "unprognostic (2.20e-1)" DGKZ "DAGK5, DAGK6, DGK-ZETA, hDGKzeta" ENSG00000149091 "Diacylglycerol kinase zeta" Q13574 11 46332905-46380554 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 223.0" "Cell type enhanced" "Detected in all" "Bergmann glia: 249.8;Extravillous trophoblasts: 171.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051336 Enhanced Supported Supported "Nuclear speckles" NA NA 15000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" 4 "Nuclear speckles" "HPA051336: " "unprognostic (4.01e-2)" "unprognostic (1.57e-1)" "unprognostic (6.88e-2)" "unprognostic (3.45e-2)" "unprognostic (9.63e-3)" "unprognostic (2.19e-2)" "unprognostic (5.03e-2)" "unprognostic (3.55e-1)" "unprognostic (2.45e-2)" "unprognostic (2.57e-1)" "unprognostic (1.17e-2)" "unprognostic (1.22e-1)" "unprognostic (1.20e-3)" "unprognostic (1.12e-3)" "unprognostic (2.86e-1)" "unprognostic (5.83e-2)" "unprognostic (1.12e-1)" "unprognostic (4.97e-2)" "unprognostic (3.64e-1)" "unprognostic (1.40e-2)" "unprognostic (1.34e-2)" "unprognostic (9.17e-3)" "potential prognostic unfavorable (1.65e-5)" "unprognostic (6.98e-2)" "unprognostic (5.96e-3)" "unprognostic (2.25e-1)" "unprognostic (1.03e-1)" "unprognostic (4.35e-2)" "unprognostic (2.99e-1)" "unprognostic (7.37e-2)" "unprognostic (2.15e-1)" DGLUCY "C14orf159, FLJ39975" ENSG00000133943 "D-glutamate cyclase" Q7Z3D6 14 91060333-91225632 "Enzymes, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 152.7" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 461.6;Choroid plexus epithelial cells: 396.6;Myonuclei: 353.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 201.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Stomach - Parietal cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "HPA041423, HPA052932" Approved Supported Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 52: Non-specific - Cellular respiration" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 1 Cytosol "HPA041423: , HPA052932: " "potential prognostic favorable (2.47e-4)" "unprognostic (2.22e-2)" "unprognostic (1.64e-1)" "unprognostic (1.35e-1)" "unprognostic (5.19e-2)" "unprognostic (2.32e-1)" "unprognostic (3.70e-1)" "unprognostic (9.25e-2)" "unprognostic (1.78e-1)" "potential prognostic favorable (7.01e-8)" "unprognostic (1.11e-3)" "potential prognostic favorable (1.88e-6)" "unprognostic (7.93e-2)" "unprognostic (5.43e-3)" "unprognostic (2.40e-2)" "unprognostic (4.87e-3)" "unprognostic (1.45e-1)" "unprognostic (4.89e-2)" "unprognostic (1.58e-1)" "unprognostic (2.77e-2)" "unprognostic (1.31e-2)" "unprognostic (4.85e-1)" "unprognostic (6.60e-2)" "unprognostic (3.43e-1)" "unprognostic (1.51e-1)" "unprognostic (1.30e-1)" "unprognostic (1.41e-1)" "unprognostic (1.96e-3)" "unprognostic (1.44e-2)" DGUOK dGK ENSG00000114956 "Deoxyguanosine kinase" Q16854 2 73926826-73958961 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Disease variant, Neuropathy, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034766, HPA057246" Approved NA NA "Cluster 41: Basophils - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 97: Non-specific - Cellular respiration" 3 "HPA034766: , HPA057246: " "unprognostic (3.49e-2)" "unprognostic (5.50e-2)" "unprognostic (3.04e-1)" "unprognostic (1.26e-1)" "unprognostic (3.15e-2)" "unprognostic (1.93e-2)" "unprognostic (6.10e-2)" "unprognostic (1.15e-2)" "unprognostic (1.48e-2)" "unprognostic (4.15e-2)" "potential prognostic unfavorable (1.56e-4)" "unprognostic (9.90e-3)" "potential prognostic unfavorable (9.98e-5)" "validated prognostic unfavorable (1.90e-4)" "validated prognostic unfavorable (2.03e-4)" "unprognostic (3.78e-2)" "unprognostic (1.49e-1)" "unprognostic (4.91e-3)" "unprognostic (3.66e-2)" "unprognostic (1.91e-1)" "unprognostic (8.92e-2)" "unprognostic (5.13e-2)" "unprognostic (1.77e-1)" "unprognostic (7.07e-2)" "unprognostic (3.21e-1)" "unprognostic (1.72e-2)" "unprognostic (1.46e-1)" "unprognostic (1.37e-1)" "unprognostic (1.71e-1)" "unprognostic (1.52e-1)" "unprognostic (5.97e-2)" DHCR24 "DCE, KIAA0018, seladin-1" ENSG00000116133 "24-dehydrocholesterol reductase" Q15392 1 54849627-54887195 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 1055.0;liver: 583.3" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 685.5;Alveolar cells type 1: 398.1;Alveolar cells type 2: 579.3;Esophageal apical cells: 287.4;Esophageal suprabasal cells: 371.8;Hepatocytes: 1036.7;Respiratory ionocytes: 251.5;Transitional alveolar cells: 317.0" "Cell type enhanced" "Detected in all" "midbrain-derived inhibitory: 122.1;oligodendrocyte: 120.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Liver - Hepatocytes, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Testis - Leydig cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017981, CAB037247, HPA063005" Enhanced NA NA "Cluster 41: Basophils - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 30: White matter - Myelination" "Cluster 15: Kidney cancer - Membrane components" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 52 "CAB037247: , HPA017981: , HPA063005: " "unprognostic (3.39e-1)" "unprognostic (1.32e-1)" "unprognostic (3.26e-1)" "unprognostic (2.90e-2)" "unprognostic (2.79e-3)" "unprognostic (2.16e-1)" "unprognostic (1.43e-1)" "unprognostic (3.17e-1)" "unprognostic (1.81e-1)" "unprognostic (2.74e-2)" "unprognostic (3.40e-2)" "unprognostic (2.70e-2)" "unprognostic (1.47e-1)" "unprognostic (6.55e-3)" "unprognostic (6.65e-2)" "unprognostic (5.41e-2)" "unprognostic (1.37e-1)" "unprognostic (9.88e-3)" "unprognostic (2.18e-1)" "unprognostic (2.51e-1)" "unprognostic (1.33e-1)" "unprognostic (8.51e-3)" "unprognostic (5.63e-2)" "unprognostic (4.05e-1)" "unprognostic (1.22e-1)" "unprognostic (1.51e-1)" "unprognostic (4.10e-1)" "unprognostic (1.93e-1)" "unprognostic (3.23e-1)" "unprognostic (6.62e-2)" "unprognostic (3.26e-2)" DHCR7 SLOS ENSG00000172893 "7-dehydrocholesterol reductase" Q9UBM7 11 71428193-71452868 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "Hydrolase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 112.5" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 64.9;Alveolar cells type 2: 96.1;Breast lactating cells: 69.2;Epididymal principal cells: 178.3;Esophageal apical cells: 71.6;Esophageal suprabasal cells: 66.9;Hepatocytes: 86.2;Respiratory ionocytes: 121.9;Syncytiotrophoblasts: 86.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Adrenal cortex cells, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044280 Approved Supported "Endoplasmic reticulum" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 76: Non-specific - Metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 10 "Endoplasmic reticulum" "HPA044280: " "unprognostic (1.56e-2)" "unprognostic (3.90e-1)" "unprognostic (1.09e-1)" "potential prognostic unfavorable (2.44e-4)" "unprognostic (5.12e-2)" "unprognostic (7.99e-2)" "unprognostic (7.70e-2)" "unprognostic (2.40e-2)" "potential prognostic unfavorable (9.90e-4)" "unprognostic (7.14e-3)" "potential prognostic favorable (7.01e-5)" "unprognostic (4.05e-2)" "unprognostic (2.05e-1)" "unprognostic (9.30e-3)" "potential prognostic unfavorable (3.23e-4)" "unprognostic (7.24e-3)" "unprognostic (4.51e-2)" "unprognostic (3.82e-1)" "unprognostic (1.19e-2)" "unprognostic (6.18e-2)" "unprognostic (2.11e-1)" "unprognostic (8.37e-3)" "unprognostic (4.85e-1)" "unprognostic (1.01e-1)" "unprognostic (1.77e-1)" "unprognostic (2.11e-1)" "unprognostic (3.80e-2)" "unprognostic (2.92e-1)" "unprognostic (2.75e-1)" "unprognostic (6.95e-2)" "unprognostic (1.61e-2)" DHDDS "DS, FLJ13102, hCIT, HDS, RP59" ENSG00000117682 "Dehydrodolichyl diphosphate synthase subunit" Q86SQ9 1 26432282-26471306 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" Transferase "Disease variant, Epilepsy, Intellectual disability, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 159.5;Cone photoreceptor cells: 279.5;Goblet cells: 127.2;Rod photoreceptor cells: 132.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026721, HPA026727" Uncertain Uncertain "Plasma membrane" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 71: Cerebellum - Nervous system development" "Cluster 25: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 79: Photoreceptor cells - Phototransduction" 2 "Plasma membrane" "HPA026721: , HPA026727: " "unprognostic (2.05e-2)" "unprognostic (1.75e-2)" "unprognostic (2.34e-1)" "unprognostic (2.99e-2)" "unprognostic (7.73e-2)" "unprognostic (2.52e-1)" "unprognostic (8.25e-2)" "unprognostic (1.64e-1)" "unprognostic (9.84e-2)" "unprognostic (5.11e-2)" "potential prognostic favorable (1.91e-6)" "unprognostic (9.43e-3)" "unprognostic (3.73e-3)" "unprognostic (4.95e-3)" "unprognostic (1.32e-2)" "unprognostic (2.63e-2)" "unprognostic (2.37e-1)" "unprognostic (7.79e-2)" "unprognostic (1.75e-1)" "unprognostic (1.11e-1)" "unprognostic (1.95e-2)" "unprognostic (2.13e-1)" "unprognostic (9.15e-2)" "unprognostic (7.55e-2)" "unprognostic (2.00e-2)" "unprognostic (1.90e-1)" "unprognostic (2.08e-1)" "unprognostic (1.39e-1)" "unprognostic (9.62e-2)" "unprognostic (1.10e-1)" "unprognostic (1.09e-1)" DHDH HUM2DD ENSG00000104808 "Dihydrodiol dehydrogenase" Q9UQ10 19 48933699-48944969 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 16.3;kidney: 16.8" "Cell type enriched" "Detected in many" 8 "Enterocytes: 224.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "basophil: 4.3" "Group enriched" "Detected in many" 33 "granulocytes: 4.3;T-cells: 2.3" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 6.3" "Kidney - Proximal tubular cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044131 Approved Approved "Nucleoplasm,Actin filaments" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 31: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 1: Enterocytes - Absorption and Digestion" 22 "Nucleoplasm, Actin filaments" "HPA044131: " "unprognostic (3.74e-2)" "unprognostic (1.47e-1)" "unprognostic (7.05e-2)" "potential prognostic favorable (3.02e-4)" "unprognostic (7.19e-2)" "unprognostic (1.77e-1)" "unprognostic (1.89e-1)" "potential prognostic favorable (4.21e-10)" "unprognostic (2.01e-3)" "unprognostic (4.00e-2)" "unprognostic (1.30e-1)" "unprognostic (7.86e-3)" "unprognostic (1.06e-1)" "unprognostic (1.43e-1)" "unprognostic (1.51e-1)" "unprognostic (5.51e-2)" "unprognostic (3.94e-1)" "unprognostic (2.68e-2)" "unprognostic (4.64e-2)" "unprognostic (4.64e-2)" "unprognostic (1.94e-2)" "unprognostic (2.19e-3)" "unprognostic (2.28e-2)" "unprognostic (1.05e-1)" "unprognostic (1.55e-1)" "potential prognostic unfavorable (6.77e-4)" DHFR ENSG00000228716 "Dihydrofolate reductase" P00374 5 80626226-80654983 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Methotrexate resistance, One-carbon metabolism" "Oxidoreductase, RNA-binding" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 446.4;Loop of henle epithelial cells: 307.4;Papillary tip epithelial cells: 244.2;Podocytes: 325.7;Proximal tubule cells: 882.7;Renal collecting duct intercalated cells: 455.3;Renal collecting duct principal cells: 228.4;Renal connecting tubule cells: 429.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Liver - Hepatocytes, Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037129, HPA051465" Uncertain Approved Mitochondria NA Yes "Cluster 9: T-regs - Cell cycle regulation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 88: Proximal tubular cells - Transmembrane transport" 49 Mitochondria "CAB037129: , HPA051465: " "unprognostic (3.41e-2)" "unprognostic (1.07e-1)" "unprognostic (2.42e-1)" "unprognostic (1.84e-2)" "unprognostic (2.53e-1)" "unprognostic (8.47e-2)" "unprognostic (2.72e-1)" "unprognostic (2.81e-1)" "unprognostic (1.17e-1)" "potential prognostic unfavorable (1.46e-4)" "unprognostic (2.78e-3)" "unprognostic (7.67e-2)" "unprognostic (8.30e-3)" "unprognostic (3.35e-3)" "unprognostic (2.07e-3)" "potential prognostic unfavorable (8.50e-4)" "unprognostic (8.24e-3)" "unprognostic (1.85e-2)" "unprognostic (1.23e-1)" "unprognostic (4.94e-2)" "unprognostic (1.01e-1)" "unprognostic (3.27e-2)" "unprognostic (2.73e-1)" "unprognostic (4.92e-2)" "unprognostic (2.31e-2)" "unprognostic (2.66e-1)" "unprognostic (2.15e-2)" "unprognostic (2.76e-2)" "unprognostic (2.01e-1)" "unprognostic (2.94e-1)" "unprognostic (1.81e-1)" DHFR2 "DHFRL1, DHFRP4, FLJ16119" ENSG00000178700 "Dihydrofolate reductase 2" Q86XF0 3 94047836-94063389 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" "One-carbon metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 42.7;Epicardial cells: 45.5;Late primary spermatocytes: 41.1;Tuft cells: 34.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Kidney - Fibroblasts, Thyroid gland - Thyroid glandular cells" HPA051465 Uncertain Supported Mitochondria NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 55: Breast - Lactation" "Cluster 7: Non-specific - Ribosome" "Cluster 63: Non-specific - Protein processing" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 12 Mitochondria "HPA051465: " "unprognostic (3.30e-2)" "unprognostic (5.52e-2)" "unprognostic (8.37e-2)" "unprognostic (4.19e-2)" "unprognostic (3.66e-2)" "unprognostic (2.49e-1)" "unprognostic (3.15e-1)" "unprognostic (1.75e-1)" "unprognostic (9.01e-3)" "potential prognostic favorable (2.23e-8)" "unprognostic (1.13e-2)" "unprognostic (3.61e-2)" "unprognostic (5.67e-2)" "unprognostic (1.24e-1)" "unprognostic (1.72e-1)" "unprognostic (1.84e-1)" "unprognostic (2.07e-3)" "unprognostic (5.86e-3)" "unprognostic (9.62e-3)" "unprognostic (4.17e-1)" "unprognostic (2.44e-1)" "unprognostic (1.67e-1)" "unprognostic (2.27e-1)" "unprognostic (1.54e-1)" "unprognostic (1.42e-1)" "unprognostic (3.02e-1)" "unprognostic (2.30e-1)" "unprognostic (1.61e-1)" "unprognostic (7.81e-3)" DHH "HHG-3, MGC35145" ENSG00000139549 "Desert hedgehog signaling molecule" O43323 12 49086656-49094801 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Developmental protein, Hydrolase, Protease, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 11 "testis: 9.8" "Group enriched" "Detected in some" 5 "Granulosa cells: 95.7;Schwann cells: 38.0;Sertoli cells: 40.7" "Cell type enriched" "Detected in some" 4 "endothelial cell: 8.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Minor Salivary Gland - Endothelial cells, Pituitary gland - Gonadotropes, Testis - Sertoli cells" "Not detected" "Not detected" "Region enriched" "Detected in some" 6 "spinal cord: 10.9" "Secreted in male reproductive system" "Developmental protein" NA NA "Cluster 67: Testis - Mixed function" "Cluster 25: Non-specific - Transcription" "Cluster 47: Leukemia - Hemostasis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 30 "unprognostic (5.07e-1)" DHODH ENSG00000102967 "Dihydroorotate dehydrogenase (quinone)" Q02127 16 72008588-72027664 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Pyrimidine biosynthesis" Oxidoreductase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "liver: 58.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 42.4;Epicardial cells: 163.7;Hepatocytes: 147.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010123, HPA011942" Approved Enhanced Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 53: Liver - Plasma proteins" "Cluster 11: White matter - Signal transduction" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 4 Mitochondria "Nucleoplasm, Cytosol" "HPA010123: , HPA011942: " "unprognostic (5.38e-2)" "unprognostic (1.10e-2)" "unprognostic (1.92e-1)" "potential prognostic unfavorable (1.51e-4)" "unprognostic (4.05e-1)" "unprognostic (3.05e-1)" "unprognostic (8.77e-2)" "unprognostic (5.58e-3)" "unprognostic (2.66e-2)" "unprognostic (9.93e-2)" "potential prognostic favorable (4.72e-5)" "unprognostic (2.65e-3)" "unprognostic (2.05e-3)" "unprognostic (1.05e-1)" "unprognostic (1.94e-3)" "unprognostic (2.00e-1)" "unprognostic (7.93e-3)" "unprognostic (3.08e-1)" "unprognostic (2.43e-3)" "unprognostic (1.18e-1)" "unprognostic (2.24e-1)" "unprognostic (5.56e-2)" "unprognostic (3.76e-2)" "unprognostic (1.23e-1)" "unprognostic (5.70e-2)" "unprognostic (1.21e-2)" "unprognostic (1.13e-1)" "unprognostic (2.03e-1)" "unprognostic (3.36e-1)" "potential prognostic unfavorable (3.01e-4)" "unprognostic (1.84e-2)" DHPS MIG13 ENSG00000095059 "Deoxyhypusine synthase" P49366 19 12675717-12681880 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hypusine biosynthesis" Transferase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bergmann glia: 19.1;Brain excitatory neurons: 22.7;Brain inhibitory neurons: 18.8;Colonocytes: 19.1;Enteric stem cells: 29.2;Enteric transient amplifying cells: 20.8;Enterocytes: 34.4;Epididymal basal cells: 18.4;Epididymal efferent duct absorptive cells: 19.2;Epididymal efferent duct ciliated cells: 19.7;Gastric chief cells: 27.3;Goblet cells: 20.8;Oligodendrocytes: 23.0;Other brain neurons: 23.9;Paneth cells: 27.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014461, HPA029413" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 15: Non-specific - Protein processing" 26 "Nucleoplasm, Cytosol" "HPA014461: , HPA029413: " "unprognostic (1.92e-1)" "potential prognostic unfavorable (1.40e-4)" "unprognostic (1.55e-1)" "unprognostic (3.00e-2)" "potential prognostic favorable (3.34e-4)" "unprognostic (2.16e-1)" "unprognostic (2.93e-1)" "unprognostic (1.58e-1)" "unprognostic (1.01e-1)" "unprognostic (3.07e-3)" "potential prognostic favorable (2.15e-6)" "unprognostic (2.10e-2)" "unprognostic (2.25e-2)" "unprognostic (1.33e-1)" "unprognostic (2.70e-1)" "unprognostic (7.44e-3)" "unprognostic (3.71e-2)" "unprognostic (7.82e-2)" "unprognostic (5.63e-3)" "unprognostic (1.18e-2)" "unprognostic (1.82e-1)" "unprognostic (4.15e-1)" "unprognostic (6.26e-2)" "unprognostic (4.52e-1)" "unprognostic (1.69e-2)" "unprognostic (3.03e-1)" "unprognostic (1.58e-1)" "unprognostic (2.09e-1)" "unprognostic (4.82e-2)" "unprognostic (2.27e-1)" "unprognostic (2.17e-1)" DHRS1 "FLJ25430, MGC20204, SDR19C1" ENSG00000157379 "Dehydrogenase/reductase 1" Q96LJ7 14 24290598-24299780 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 70.4;liver: 59.4" "Cell type enhanced" "Detected in many" "Astrocytes: 13.2;Bergmann glia: 16.0;Esophageal apical cells: 19.5;Late spermatids: 22.5;Microglia: 16.5;Oligodendrocytes: 17.7;Renal collecting duct principal cells: 13.2;Suprabasal keratinocytes: 16.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Liver - Hepatocytes, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000599, HPA076886" Approved Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 98: Neurons - Neurotransmission & signaling" 30 Nucleoplasm "Centrosome, Cytosol" "HPA000599: , HPA076886: " "unprognostic (2.65e-2)" "unprognostic (1.99e-2)" "unprognostic (5.82e-3)" "unprognostic (1.26e-1)" "unprognostic (3.11e-1)" "unprognostic (1.09e-2)" "unprognostic (2.29e-1)" "unprognostic (2.41e-2)" "unprognostic (8.54e-2)" "unprognostic (3.85e-1)" "potential prognostic favorable (6.06e-9)" "unprognostic (6.76e-2)" "unprognostic (3.26e-3)" "validated prognostic favorable (1.92e-5)" "validated prognostic favorable (6.72e-4)" "unprognostic (1.52e-2)" "unprognostic (6.97e-2)" "unprognostic (2.45e-2)" "unprognostic (7.17e-2)" "unprognostic (2.22e-1)" "unprognostic (1.57e-1)" "unprognostic (6.98e-3)" "unprognostic (1.56e-1)" "unprognostic (8.42e-2)" "unprognostic (2.93e-2)" "unprognostic (1.20e-1)" "unprognostic (1.58e-1)" "unprognostic (9.26e-2)" "unprognostic (1.66e-1)" "unprognostic (2.77e-1)" "unprognostic (7.30e-2)" DHRS11 "MGC4172, SDR24C1" ENSG00000278535 "Dehydrogenase/reductase 11" Q6UWP2 17 36591879-36600804 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "intestine: 203.2" "Cell type enhanced" "Detected in some" "Astrocytes: 6.0;Brain excitatory neurons: 10.5;Brain inhibitory neurons: 13.1;Choroid plexus epithelial cells: 12.1;Colonocytes: 6.2;Distal convoluted tubule cells: 8.6;Enterocytes: 10.7;Ependymal cells: 7.1;Loop of henle epithelial cells: 6.8;Other brain neurons: 14.0;Renal collecting duct intercalated cells: 6.5;Renal connecting tubule cells: 8.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Minor Salivary Gland - Minor salivary gland basal cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041226, HPA048236, HPA053623" Enhanced Approved "Golgi apparatus,Cytosol" "Secreted to digestive system" Enzyme NA NA 51000 "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 47: Leukemia - Hemostasis" "Cluster 98: Neurons - Neurotransmission & signaling" Cytosol "Golgi apparatus" "HPA041226: , HPA048236: , HPA053623: " "unprognostic (3.31e-2)" "unprognostic (3.60e-2)" "unprognostic (1.47e-1)" "unprognostic (2.87e-1)" "unprognostic (2.06e-2)" "unprognostic (1.96e-1)" "unprognostic (2.10e-3)" "unprognostic (9.49e-2)" "unprognostic (1.46e-1)" "unprognostic (1.04e-2)" "unprognostic (7.83e-2)" "unprognostic (9.87e-3)" "unprognostic (6.83e-2)" "unprognostic (2.53e-2)" "unprognostic (7.87e-2)" "unprognostic (1.21e-1)" "unprognostic (5.41e-2)" "unprognostic (2.71e-2)" "unprognostic (7.88e-2)" "unprognostic (8.49e-2)" "unprognostic (7.27e-2)" "unprognostic (4.92e-3)" "unprognostic (5.56e-2)" "unprognostic (1.16e-1)" "unprognostic (1.81e-1)" "unprognostic (2.55e-1)" "unprognostic (4.06e-2)" "unprognostic (7.13e-2)" DHRS12 "FLJ13639, SDR40C1" ENSG00000102796 "Dehydrogenase/reductase 12" A0PJE2 13 51767993-51804163 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 47.3" "Cell type enhanced" "Detected in many" "Early spermatids: 17.8;Epididymal efferent duct absorptive cells: 19.1;Late spermatids: 57.5;Oocytes: 23.0;Pancreatic acinar cells: 23.4;Parietal cells: 23.0" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 106.2" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Skeletal muscle - Fibroblasts" "CAB034238, HPA057028, HPA058315" Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 8: Pancreas - Proteolysis" "Cluster 55: Non-specific - Transcription" "Cluster 19: Non-specific - Unknown function" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" Nucleoplasm "Golgi apparatus, Vesicles" "CAB034238: , HPA057028: , HPA058315: " "unprognostic (1.55e-3)" "unprognostic (2.42e-3)" "unprognostic (8.19e-2)" "unprognostic (4.33e-2)" "unprognostic (2.13e-2)" "unprognostic (5.99e-2)" "unprognostic (4.14e-2)" "unprognostic (8.74e-2)" "unprognostic (1.30e-1)" "unprognostic (4.98e-3)" "potential prognostic favorable (8.05e-10)" "unprognostic (7.70e-3)" "potential prognostic favorable (1.41e-4)" "unprognostic (1.31e-2)" "unprognostic (1.12e-3)" "unprognostic (2.17e-1)" "unprognostic (7.94e-2)" "unprognostic (4.75e-2)" "unprognostic (1.04e-1)" "unprognostic (5.32e-2)" "unprognostic (8.88e-3)" "unprognostic (5.40e-3)" "unprognostic (3.73e-1)" "unprognostic (1.79e-1)" "unprognostic (2.54e-1)" "unprognostic (9.10e-2)" "unprognostic (6.20e-3)" "unprognostic (4.77e-2)" "unprognostic (1.29e-1)" "unprognostic (2.38e-1)" "unprognostic (1.97e-3)" DHRS13 "MGC23280, SDR7C5" ENSG00000167536 "Dehydrogenase/reductase 13" Q6UX07 17 28897781-28903079 "Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 39.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 34.7;Erythrocyte progenitors: 37.5;Neutrophils: 82.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "neutrophil: 55.5" "Lineage enriched" "Detected in all" 5 "granulocytes: 55.5" "Low cancer specificity" "Detected in all" "Heart muscle - Macrophages, Prostate - Prostate basal glandular cells, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022991 Uncertain Approved Vesicles "Secreted - unknown location" Enzyme NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 15: Bone marrow - Innate immune response" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 27: Breast cancer - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" 3 Vesicles "HPA022991: " "unprognostic (2.18e-2)" "unprognostic (2.41e-2)" "unprognostic (6.80e-2)" "unprognostic (2.66e-2)" "unprognostic (2.33e-1)" "unprognostic (1.22e-1)" "unprognostic (8.19e-3)" "unprognostic (1.71e-1)" "unprognostic (1.08e-1)" "unprognostic (4.07e-3)" "unprognostic (1.02e-3)" "unprognostic (6.52e-2)" "unprognostic (3.33e-1)" "validated prognostic unfavorable (9.20e-5)" "validated prognostic unfavorable (3.63e-6)" "unprognostic (2.69e-1)" "unprognostic (1.83e-1)" "unprognostic (2.00e-2)" "potential prognostic favorable (2.50e-4)" "unprognostic (1.41e-1)" "unprognostic (4.25e-2)" "unprognostic (3.35e-3)" "unprognostic (8.75e-3)" "unprognostic (1.64e-1)" "unprognostic (8.90e-2)" "unprognostic (2.88e-1)" "unprognostic (3.88e-1)" "unprognostic (1.43e-1)" "unprognostic (4.22e-1)" "unprognostic (2.46e-2)" "unprognostic (6.63e-2)" DHRS2 "HEP27, SDR25C1" ENSG00000100867 "Dehydrogenase/reductase 2" Q13268 14 23630115-23645639 "Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 316.3;urinary bladder: 417.5" "Cell type enriched" "Detected in many" 6 "Urothelial cells: 3414.2" "Cell type enhanced" "Detected in single" "hippocampal dentate gyrus: 1.5" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 782.0;Kidney Chromophobe (TCGA): 322.4" "Group enriched" "Detected in some" 5 "hypothalamus: 2.0;midbrain: 2.0;pons: 3.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 226.5;Sarcoma: 227.3" "Pituitary gland - Gonadotropes, Skin - Sebaceous gland cells" "Region enriched" "Detected in single" 4 "cerebellum: 2.4" "HPA053915, HPA069551" Enhanced Supported Nucleoplasm,Mitochondria No NA 4600 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 27: Breast cancer - Unknown function" "Cluster 69: Urothelial cells - Basic cellular functions" 3 Mitochondria Nucleoplasm "HPA053915: , HPA069551: " "unprognostic (2.41e-2)" "unprognostic (4.83e-1)" "unprognostic (9.83e-2)" "unprognostic (3.14e-2)" "unprognostic (2.50e-2)" "unprognostic (3.20e-2)" "unprognostic (8.53e-3)" "unprognostic (6.92e-3)" "unprognostic (3.95e-1)" "potential prognostic unfavorable (8.70e-5)" "unprognostic (2.37e-3)" "unprognostic (5.63e-2)" "unprognostic (7.42e-2)" "unprognostic (2.29e-2)" "unprognostic (2.55e-2)" "unprognostic (2.07e-2)" "unprognostic (3.79e-2)" "unprognostic (3.30e-2)" "unprognostic (1.22e-2)" "unprognostic (4.80e-2)" "unprognostic (4.35e-3)" "unprognostic (1.15e-1)" "unprognostic (2.39e-1)" "unprognostic (4.41e-1)" "unprognostic (4.60e-2)" "unprognostic (1.44e-1)" "unprognostic (4.00e-1)" "unprognostic (2.83e-1)" "unprognostic (1.23e-2)" DHRS3 "RDH17, retSDR1, Rsdr1, SDR1, SDR16C1" ENSG00000162496 "Dehydrogenase/reductase 3" O75911 1 12567910-12618210 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 238.1" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 594.8;Late spermatids: 561.2;Podocytes: 548.7;Prostatic hillock cells: 644.6;Salivary duct cells: 420.9" "Group enriched" "Detected in many" 4 "astrocyte: 70.8;central nervous system macrophage: 119.0;choroid plexus epithelial cell: 102.1;endothelial cell: 69.6;ependymal cell: 61.2;fibroblast: 57.2;leukocyte: 72.0;vascular associated smooth muscle cell: 50.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "gdT-cell: 87.0;MAIT T-cell: 63.2;memory CD4 T-cell: 47.0;memory CD8 T-cell: 41.0;myeloid DC: 24.1;naive CD4 T-cell: 79.4;naive CD8 T-cell: 50.2;NK-cell: 41.2" "Group enriched" "Detected in many" 5 "dendritic cells: 24.1;NK-cells: 41.2;T-cells: 87.0" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010844 Supported Approved Nucleoli,Mitochondria NA NA "Cluster 11: T-cells - Unknown function" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 12: Non-specific - Vasculature" "Cluster 69: Skin cancer - ECM organization" "Cluster 51: Secretory epithelial cells - Mixed function" 4 Mitochondria Nucleoli "HPA010844: " "unprognostic (4.18e-2)" "unprognostic (1.18e-1)" "unprognostic (3.75e-1)" "unprognostic (2.53e-1)" "unprognostic (4.70e-3)" "unprognostic (6.42e-2)" "unprognostic (1.35e-1)" "unprognostic (4.91e-2)" "unprognostic (1.64e-1)" "unprognostic (1.94e-1)" "validated prognostic favorable (7.22e-7)" "validated prognostic favorable (2.16e-4)" "unprognostic (3.50e-1)" "unprognostic (3.87e-2)" "unprognostic (1.35e-1)" "unprognostic (1.99e-2)" "unprognostic (1.13e-1)" "unprognostic (7.16e-2)" "unprognostic (6.76e-3)" "unprognostic (4.33e-2)" "unprognostic (8.68e-2)" "unprognostic (3.96e-3)" "unprognostic (5.77e-2)" "unprognostic (4.42e-1)" "unprognostic (1.20e-1)" "unprognostic (5.26e-2)" "unprognostic (2.94e-2)" "unprognostic (5.92e-2)" "unprognostic (2.86e-1)" "unprognostic (5.37e-3)" "unprognostic (3.99e-2)" DHRS4 "FLJ11008, humNRDR, SCAD-SRL, SDR-SRL, SDR25C2" ENSG00000157326 "Dehydrogenase/reductase 4" Q9BTZ2 14 23953734-23969279 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 36.4;Hepatocytes: 21.5;Megakaryocytes: 24.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes" HPA023972 Uncertain Approved "Nuclear membrane,Vesicles" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 72: Kidney - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 17: Non-specific - RNA processing" 3 Vesicles "Nuclear membrane" "HPA023972: " "unprognostic (2.23e-2)" "unprognostic (7.94e-2)" "unprognostic (1.31e-2)" "unprognostic (1.14e-2)" "unprognostic (1.36e-2)" "unprognostic (1.56e-2)" "unprognostic (1.76e-1)" "unprognostic (7.77e-2)" "unprognostic (4.33e-2)" "unprognostic (5.40e-3)" "potential prognostic favorable (2.86e-6)" "unprognostic (1.72e-2)" "unprognostic (1.41e-1)" "potential prognostic favorable (7.24e-4)" "unprognostic (9.74e-3)" "unprognostic (2.13e-1)" "unprognostic (1.25e-1)" "unprognostic (6.67e-2)" "unprognostic (3.36e-1)" "unprognostic (2.19e-1)" "unprognostic (2.62e-2)" "unprognostic (5.58e-3)" "potential prognostic favorable (5.56e-4)" "unprognostic (4.26e-2)" "unprognostic (1.00e-1)" "unprognostic (4.79e-3)" "unprognostic (2.22e-1)" "unprognostic (2.43e-1)" "unprognostic (9.07e-2)" "unprognostic (7.87e-2)" "unprognostic (1.35e-2)" DHRS4L2 SDR25C3 ENSG00000187630 "Dehydrogenase/reductase 4 like 2" Q6PKH6 14 23969874-24006408 "Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 122.6" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 15.5;Late primary spermatocytes: 17.2;Late spermatids: 13.5;Loop of henle epithelial cells: 13.3;Papillary tip epithelial cells: 12.0;Parietal cells: 10.6;Podocytes: 10.1;Proximal tubule cells: 27.0;Renal collecting duct intercalated cells: 10.1;Renal collecting duct principal cells: 8.8;Renal connecting tubule cells: 9.6" "Cell type enhanced" "Detected in some" "pericyte: 2.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Secreted - unknown location" Enzyme NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 88: Proximal tubular cells - Transmembrane transport" 2 "unprognostic (1.64e-3)" "unprognostic (6.84e-2)" "unprognostic (1.75e-3)" "potential prognostic favorable (2.18e-4)" "unprognostic (1.81e-2)" "unprognostic (1.26e-1)" "unprognostic (1.67e-1)" "unprognostic (6.55e-3)" "unprognostic (1.17e-1)" "unprognostic (1.02e-2)" "unprognostic (2.20e-3)" "unprognostic (1.31e-1)" "unprognostic (2.71e-1)" "unprognostic (2.23e-2)" "unprognostic (1.96e-2)" "unprognostic (1.90e-1)" "unprognostic (1.52e-1)" "unprognostic (7.82e-3)" "unprognostic (3.55e-1)" "unprognostic (1.81e-3)" "unprognostic (1.49e-2)" "unprognostic (9.71e-3)" "unprognostic (8.00e-3)" "unprognostic (4.22e-2)" "unprognostic (1.31e-1)" "unprognostic (3.48e-2)" "unprognostic (2.70e-1)" "unprognostic (5.83e-2)" "unprognostic (2.14e-1)" "unprognostic (1.00e-1)" "unprognostic (1.73e-1)" DHRS7 "retDSR4, SDR34C1" ENSG00000100612 "Dehydrogenase/reductase 7" Q9Y394 14 60144119-60169856 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 634.3" "Cell type enhanced" "Detected in many" "Breast lactating cells: 357.8;Enterocytes: 789.5;Epididymal clear cells: 420.5;Neutrophils: 407.9;Prostatic glandular cells: 1078.1;Salivary acinar cells: 449.4" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in all" 6 "Kidney Chromophobe (TCGA): 823.9;Prostate Adenocarcinoma (TCGA): 854.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Pancreas - Macrophages, Prostate - Prostate glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031121, HPA078401" Enhanced Approved Nucleoplasm,Mitochondria No No "Cluster 35: Neutrophils - Protein binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 11 "Nucleoplasm, Mitochondria" "HPA031121: , HPA078401: " "unprognostic (3.54e-2)" "unprognostic (5.06e-2)" "unprognostic (3.59e-1)" "unprognostic (3.12e-2)" "unprognostic (1.13e-1)" "unprognostic (1.50e-1)" "unprognostic (4.90e-1)" "unprognostic (2.33e-1)" "potential prognostic unfavorable (9.00e-5)" "unprognostic (2.88e-1)" "potential prognostic favorable (5.38e-9)" "unprognostic (1.56e-1)" "unprognostic (1.78e-1)" "unprognostic (5.29e-2)" "unprognostic (1.93e-1)" "unprognostic (3.10e-3)" "unprognostic (7.37e-2)" "unprognostic (2.03e-1)" "unprognostic (6.45e-3)" "unprognostic (5.10e-3)" "unprognostic (7.24e-2)" "unprognostic (9.85e-2)" "unprognostic (1.24e-2)" "unprognostic (1.50e-1)" "unprognostic (4.33e-2)" "unprognostic (1.58e-2)" "unprognostic (6.26e-2)" "unprognostic (9.19e-3)" "unprognostic (2.54e-1)" "unprognostic (9.41e-2)" "unprognostic (7.12e-2)" DHRS7B "CGI-93, DKFZp566O084, MGC8916, SDR32C1" ENSG00000109016 "Dehydrogenase/reductase 7B" Q6IAN0 17 21123364-21193265 "Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Myonuclei: 207.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012132, HPA016873" Uncertain Approved "Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 42: Non-specific - Unknown function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 29 "Plasma membrane, Cell Junctions, Cytosol" "HPA012132: , HPA016873: " "unprognostic (4.06e-2)" "unprognostic (7.95e-2)" "unprognostic (9.00e-2)" "unprognostic (1.20e-1)" "unprognostic (1.40e-1)" "unprognostic (4.73e-2)" "unprognostic (2.87e-1)" "unprognostic (3.70e-1)" "unprognostic (1.52e-1)" "unprognostic (1.55e-1)" "unprognostic (6.29e-2)" "unprognostic (1.82e-3)" "potential prognostic favorable (5.96e-7)" "unprognostic (2.41e-1)" "unprognostic (8.16e-2)" "unprognostic (3.19e-1)" "unprognostic (3.07e-1)" "unprognostic (2.83e-1)" "unprognostic (1.54e-2)" "unprognostic (3.54e-1)" "unprognostic (5.80e-2)" "unprognostic (3.62e-1)" "unprognostic (1.30e-1)" "unprognostic (1.83e-1)" "unprognostic (3.06e-2)" "unprognostic (8.53e-2)" "unprognostic (3.50e-2)" "unprognostic (2.36e-2)" "unprognostic (6.02e-2)" "unprognostic (2.13e-1)" "potential prognostic favorable (2.64e-4)" DHRS7C SDR32C2 ENSG00000184544 "Dehydrogenase/reductase 7C" A6NNS2 17 9771434-9791592 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 64 "heart muscle: 102.3;skeletal muscle: 288.6;tongue: 342.6" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 4.2;Corticotrophs: 5.0;Early spermatids: 7.9;Late primary spermatocytes: 3.7;Late spermatids: 27.7;Myonuclei: 22.4;Thymic myoid cells: 4.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Region enhanced" "Detected in single" "thalamus: 1.7" "Secreted in other tissues" Enzyme NA NA "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 11: Neuronal - Sensory perception" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" DHRS9 "3alpha-HSD, RDH15, RDHL, RETSDR8, SDR9C4" ENSG00000073737 "Dehydrogenase/reductase 9" Q9BPW9 2 169064789-169096167 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 50.2;intestine: 66.0" "Cell type enhanced" "Detected in many" "Colonocytes: 385.2;Conjunctival goblet cells: 116.5;Early spermatids: 158.8;Esophageal apical cells: 427.1;Foveolar cells: 161.7;Goblet cells: 136.5;Late primary spermatocytes: 112.6;Mast cells: 120.7;Microglia: 113.7;Neutrophil progenitors: 120.4;Neutrophils: 155.1;Respiratory ciliated cells: 115.8;Respiratory secretory cells: 186.2;Syncytiotrophoblasts: 577.4" "Cell type enriched" "Detected in some" 49 "central nervous system macrophage: 119.0" "Cancer enhanced" "Detected in many" "Pancreatic Adenocarcinoma (TCGA): 61.7" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "basophil: 259.3;eosinophil: 99.5;neutrophil: 77.6" "Lineage enriched" "Detected in many" 10 "granulocytes: 259.3" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 144.7;pancreatic cancer: 82.9" "Skin - Sebaceous gland cells, Spleen - Neutrophils_2, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA036491, HPA036667" Approved NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 1 "HPA036491: , HPA036667: " "unprognostic (8.22e-3)" "unprognostic (1.61e-1)" "unprognostic (3.00e-2)" "unprognostic (1.90e-3)" "unprognostic (2.12e-1)" "unprognostic (3.95e-2)" "unprognostic (6.57e-2)" "unprognostic (4.69e-3)" "unprognostic (3.56e-1)" "unprognostic (5.24e-3)" "unprognostic (4.56e-1)" "unprognostic (8.29e-2)" "unprognostic (1.55e-1)" "unprognostic (1.63e-1)" "unprognostic (1.31e-1)" "unprognostic (2.32e-2)" "unprognostic (4.32e-2)" "unprognostic (2.11e-1)" "potential prognostic unfavorable (9.63e-4)" "unprognostic (3.06e-2)" "potential prognostic unfavorable (1.05e-4)" "unprognostic (1.00e-2)" "unprognostic (1.48e-1)" "unprognostic (8.06e-2)" "unprognostic (6.24e-2)" "unprognostic (2.18e-1)" "unprognostic (3.70e-2)" "unprognostic (1.06e-2)" "unprognostic (5.32e-2)" "unprognostic (8.51e-2)" DHRSX "DHRS5X, DHRS5Y, DHRSXY, DHRSY, SDR46C1, SDR7C6" ENSG00000169084 "Dehydrogenase/reductase X-linked" Q8N5I4 X 2219506-2502805 "Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 983.7" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "HPA003035, HPA075955" Approved Uncertain "Mitotic spindle,Cytosol" "Secreted to blood" Enzyme Yes NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 70: Non-specific - Protein processing" "Cluster 46: Brainstem - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 15 Cytosol "Mitotic spindle" "HPA003035: , HPA075955: " "unprognostic (2.55e-1)" "unprognostic (1.29e-2)" "unprognostic (4.56e-2)" "unprognostic (1.25e-1)" "unprognostic (1.33e-2)" "unprognostic (1.08e-1)" "unprognostic (5.73e-2)" "unprognostic (1.12e-1)" "unprognostic (1.29e-1)" "potential prognostic favorable (7.84e-4)" "unprognostic (1.58e-1)" "unprognostic (1.65e-1)" "unprognostic (3.35e-1)" "potential prognostic unfavorable (3.05e-4)" "unprognostic (2.02e-2)" "unprognostic (1.78e-1)" "unprognostic (2.10e-1)" "unprognostic (2.72e-1)" "unprognostic (1.52e-1)" "unprognostic (3.96e-2)" "unprognostic (8.80e-2)" "unprognostic (2.80e-1)" "unprognostic (2.84e-1)" "unprognostic (6.15e-3)" "unprognostic (7.75e-2)" "unprognostic (3.17e-2)" "unprognostic (2.74e-1)" "unprognostic (3.04e-1)" "unprognostic (5.30e-2)" DHTKD1 "CMT2Q, DKFZP762M115, KIAA1630, MGC3090" ENSG00000181192 "Dehydrogenase E1 and transketolase domain containing 1" Q96HY7 10 12068954-12123221 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis Oxidoreductase "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 121.0" "Cell type enhanced" "Detected in many" "Hepatocytes: 400.6;Proximal tubule cells: 180.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Spleen - B-cells (Spleen), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037949, HPA037950, HPA066098" Enhanced Supported Mitochondria NA NA "Cluster 32: Basophils - Transcription" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 25: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 88: Proximal tubular cells - Transmembrane transport" 4 Mitochondria "HPA037949: , HPA037950: , HPA066098: " "unprognostic (1.26e-2)" "unprognostic (1.91e-2)" "unprognostic (4.04e-1)" "unprognostic (3.32e-1)" "unprognostic (1.12e-1)" "unprognostic (9.33e-2)" "unprognostic (1.67e-1)" "potential prognostic favorable (3.40e-6)" "unprognostic (1.39e-3)" "unprognostic (4.48e-2)" "potential prognostic favorable (2.45e-6)" "unprognostic (1.46e-2)" "unprognostic (2.85e-2)" "unprognostic (4.80e-3)" "unprognostic (1.28e-3)" "unprognostic (9.53e-2)" "unprognostic (1.75e-2)" "unprognostic (1.05e-1)" "unprognostic (1.99e-1)" "unprognostic (3.15e-2)" "unprognostic (1.09e-1)" "unprognostic (3.51e-1)" "unprognostic (2.04e-1)" "unprognostic (2.87e-1)" "unprognostic (9.23e-2)" "unprognostic (3.91e-2)" "unprognostic (9.80e-2)" "unprognostic (2.52e-1)" "unprognostic (1.34e-1)" "unprognostic (2.54e-3)" "unprognostic (4.10e-2)" DHX15 "DBP1, DDX15, HRH2, PRP43, PRPF43, PrPp43p" ENSG00000109606 "DEAH-box helicase 15" O43143 4 24517441-24584554 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity, mRNA processing, mRNA splicing" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047047 Approved Enhanced "Nuclear speckles" NA NA 610000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 17: Non-specific - RNA processing" 103 "Nuclear speckles" "HPA047047: " "unprognostic (1.93e-1)" "unprognostic (1.01e-2)" "unprognostic (5.52e-2)" "unprognostic (7.06e-2)" "potential prognostic favorable (8.79e-4)" "unprognostic (6.45e-2)" "unprognostic (1.04e-1)" "unprognostic (1.40e-2)" "unprognostic (1.26e-1)" "potential prognostic unfavorable (1.75e-4)" "validated prognostic favorable (1.16e-8)" "validated prognostic favorable (8.41e-5)" "unprognostic (2.77e-1)" "unprognostic (9.93e-3)" "unprognostic (1.99e-2)" "unprognostic (2.30e-3)" "unprognostic (7.61e-3)" "unprognostic (1.52e-1)" "unprognostic (5.35e-2)" "unprognostic (4.66e-1)" "unprognostic (1.87e-1)" "potential prognostic unfavorable (2.95e-5)" "unprognostic (2.25e-2)" "unprognostic (4.23e-2)" "unprognostic (6.13e-2)" "unprognostic (4.20e-1)" "unprognostic (9.10e-2)" "unprognostic (5.77e-2)" "unprognostic (1.67e-1)" "unprognostic (2.30e-2)" "unprognostic (2.59e-1)" DHX16 "DBP2, DDX16, Prp2, PRPF2" ENSG00000204560 "DEAH-box helicase 16" O60231 6 30653119-30673006 "Disease related genes, Enzymes, Essential proteins, Potential drug targets, Predicted intracellular proteins" "Immunity, Innate immunity, mRNA processing, mRNA splicing" "Helicase, Hydrolase" "Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 78.3;Late primary spermatocytes: 131.6;Late spermatids: 57.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051455 Supported Supported Nucleoplasm NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 24: Non-specific - Transcription" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 28: Non-specific - Nuclear processes" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 40 Nucleoplasm "HPA051455: " "unprognostic (6.53e-2)" "unprognostic (1.41e-1)" "unprognostic (4.07e-1)" "unprognostic (1.96e-3)" "unprognostic (2.59e-1)" "unprognostic (5.96e-2)" "unprognostic (2.36e-1)" "potential prognostic favorable (5.05e-4)" "unprognostic (2.89e-1)" "unprognostic (4.87e-2)" "validated prognostic favorable (8.59e-4)" "validated prognostic favorable (8.56e-4)" "unprognostic (1.78e-1)" "unprognostic (9.78e-3)" "unprognostic (6.02e-2)" "unprognostic (1.33e-1)" "unprognostic (2.06e-2)" "unprognostic (3.47e-1)" "unprognostic (4.54e-2)" "unprognostic (3.55e-1)" "unprognostic (2.25e-1)" "unprognostic (2.93e-1)" "unprognostic (3.16e-2)" "unprognostic (2.82e-1)" "unprognostic (7.19e-2)" "unprognostic (2.20e-1)" "unprognostic (1.29e-2)" "unprognostic (2.18e-1)" "unprognostic (4.29e-1)" "unprognostic (4.45e-2)" "unprognostic (8.69e-2)" DHX29 DDX29 ENSG00000067248 "DExH-box helicase 29" Q7Z478 5 55256055-55307694 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Helicase, Hydrolase, Initiation factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038317, HPA038318" Approved Approved Cytosol NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 7: Non-specific - Transcription" 19 Cytosol "HPA038317: , HPA038318: " "unprognostic (4.36e-1)" "unprognostic (1.72e-2)" "unprognostic (3.63e-1)" "unprognostic (2.88e-2)" "unprognostic (9.65e-2)" "unprognostic (7.50e-2)" "unprognostic (9.96e-2)" "unprognostic (4.97e-3)" "unprognostic (1.34e-1)" "potential prognostic unfavorable (1.97e-4)" "potential prognostic favorable (4.95e-6)" "unprognostic (1.48e-2)" "unprognostic (1.15e-1)" "unprognostic (1.80e-2)" "unprognostic (7.36e-2)" "unprognostic (1.81e-1)" "unprognostic (1.01e-1)" "unprognostic (1.08e-1)" "unprognostic (1.68e-1)" "unprognostic (1.26e-3)" "potential prognostic unfavorable (3.84e-4)" "unprognostic (9.45e-3)" "unprognostic (1.95e-1)" "unprognostic (9.23e-2)" "unprognostic (1.92e-1)" "unprognostic (1.91e-1)" "unprognostic (1.79e-1)" "unprognostic (3.59e-2)" "unprognostic (5.39e-1)" "unprognostic (2.82e-2)" "unprognostic (1.10e-1)" DHX30 "DDX30, FLJ11214, KIAA0890" ENSG00000132153 "DExH-box helicase 30" Q7L2E3 3 47802909-47850195 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Ribosome biogenesis" "Helicase, Hydrolase, RNA-binding" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 229.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034806 Supported Supported Mitochondria,Cytosol NA NA 38000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 67: Testis - Mixed function" "Cluster 14: Neurons - Synaptic function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 89 Mitochondria Cytosol "HPA034806: " "unprognostic (3.07e-1)" "unprognostic (1.62e-1)" "unprognostic (8.44e-2)" "unprognostic (1.42e-1)" "unprognostic (3.41e-1)" "unprognostic (1.15e-1)" "unprognostic (3.62e-1)" "unprognostic (1.05e-2)" "unprognostic (4.21e-1)" "unprognostic (3.69e-3)" "unprognostic (1.09e-3)" "unprognostic (1.52e-2)" "unprognostic (1.16e-2)" "validated prognostic unfavorable (1.03e-4)" "validated prognostic unfavorable (2.61e-4)" "unprognostic (5.12e-2)" "unprognostic (2.25e-2)" "unprognostic (2.73e-1)" "unprognostic (5.95e-2)" "unprognostic (1.70e-1)" "unprognostic (8.95e-2)" "unprognostic (6.38e-2)" "unprognostic (3.81e-1)" "unprognostic (1.64e-3)" "unprognostic (2.84e-2)" "unprognostic (8.77e-3)" "unprognostic (2.50e-1)" "unprognostic (1.13e-1)" "unprognostic (7.60e-2)" "unprognostic (1.05e-1)" "unprognostic (1.47e-2)" DHX32 "DDX32, DHLP1, FLJ10694, FLJ10889" ENSG00000089876 "DEAH-box helicase 32 (putative)" Q7L7V1 10 125836337-125896436 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 280.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Prostate basal glandular cells, Spleen - Endothelial cells, Stomach - Gastric mucous cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048872 Approved NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 21: Testis - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 52: Non-specific - Mitochondria" "Cluster 70: Intestinal goblet cells - Mucin production" 1 "HPA048872: " "unprognostic (6.48e-2)" "unprognostic (1.96e-2)" "unprognostic (3.15e-2)" "unprognostic (1.76e-1)" "unprognostic (2.72e-1)" "unprognostic (4.85e-2)" "unprognostic (1.32e-1)" "unprognostic (6.39e-2)" "unprognostic (1.28e-1)" "unprognostic (1.08e-1)" "unprognostic (1.56e-3)" "unprognostic (8.71e-2)" "unprognostic (3.30e-1)" "unprognostic (2.17e-2)" "unprognostic (2.77e-1)" "unprognostic (2.22e-2)" "unprognostic (2.34e-1)" "unprognostic (1.48e-1)" "unprognostic (5.99e-3)" "unprognostic (2.12e-1)" "unprognostic (1.04e-3)" "potential prognostic unfavorable (1.10e-4)" "unprognostic (1.45e-3)" "unprognostic (1.82e-3)" "unprognostic (2.09e-1)" "unprognostic (2.27e-1)" "unprognostic (4.06e-1)" "unprognostic (5.40e-2)" "unprognostic (1.94e-2)" "unprognostic (1.71e-1)" "unprognostic (1.84e-1)" DHX33 "DDX33, DKFZp762F2011, FLJ21972" ENSG00000005100 "DEAH-box helicase 33" Q9H6R0 17 5440917-5468982 "Enzymes, Essential proteins, Predicted intracellular proteins" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA071536, HPA073875" Supported Enhanced Nucleoli NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 42: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 12 Nucleoli "HPA071536: , HPA073875: " "unprognostic (7.94e-2)" "unprognostic (3.70e-3)" "unprognostic (1.68e-1)" "unprognostic (7.15e-2)" "unprognostic (4.85e-1)" "unprognostic (7.31e-2)" "unprognostic (6.98e-2)" "unprognostic (2.12e-2)" "unprognostic (2.95e-1)" "unprognostic (1.80e-2)" "unprognostic (2.09e-2)" "unprognostic (2.03e-2)" "unprognostic (1.27e-1)" "unprognostic (3.76e-2)" "unprognostic (2.73e-1)" "unprognostic (3.75e-3)" "unprognostic (3.62e-2)" "unprognostic (3.05e-1)" "unprognostic (5.14e-2)" "unprognostic (1.86e-1)" "unprognostic (2.16e-1)" "unprognostic (2.75e-1)" "unprognostic (3.38e-2)" "unprognostic (2.11e-3)" "unprognostic (1.41e-2)" "unprognostic (2.99e-1)" "unprognostic (2.04e-2)" "unprognostic (1.10e-1)" "unprognostic (1.96e-1)" "unprognostic (1.12e-2)" "unprognostic (6.81e-2)" DHX34 "DDX34, KIAA0134" ENSG00000134815 "DExH-box helicase 34" Q14147 19 47349315-47382704 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 92.9;Late spermatids: 106.8;monocytes: 114.4;Neutrophils: 423.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 11.7" "Lineage enriched" "Detected in many" 6 "granulocytes: 11.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042159, HPA043558" Uncertain Approved Nucleoplasm NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 67: Testis - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 2 Nucleoplasm "HPA042159: , HPA043558: " "unprognostic (2.17e-1)" "unprognostic (3.37e-1)" "unprognostic (3.83e-2)" "unprognostic (3.25e-1)" "unprognostic (3.66e-1)" "unprognostic (1.55e-2)" "unprognostic (2.77e-1)" "unprognostic (3.46e-2)" "unprognostic (6.70e-2)" "unprognostic (2.09e-1)" "unprognostic (4.60e-1)" "unprognostic (6.87e-2)" "unprognostic (2.12e-2)" "potential prognostic unfavorable (3.87e-6)" "unprognostic (7.01e-2)" "unprognostic (7.31e-2)" "unprognostic (7.46e-3)" "unprognostic (4.95e-2)" "unprognostic (8.79e-2)" "unprognostic (1.70e-1)" "unprognostic (2.50e-2)" "unprognostic (7.46e-2)" "unprognostic (1.72e-1)" "unprognostic (3.41e-2)" "unprognostic (1.08e-2)" "unprognostic (5.67e-3)" "unprognostic (3.78e-2)" "unprognostic (9.44e-2)" "unprognostic (2.23e-1)" "unprognostic (3.80e-2)" "unprognostic (4.79e-2)" DHX35 "C20orf15, DDX35, FLJ22759, KAIA0875" ENSG00000101452 "DEAH-box helicase 35" Q9H5Z1 20 38962299-39039723 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 91.0;Myonuclei: 77.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Prostate - Smooth muscle cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054451, HPA062700" Uncertain Approved "Nucleoplasm,Nuclear bodies,Centrosome" No No "Cluster 14: Non-specific - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 53: Neurons - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 84: Apical squamous epithelium - Cornification" 18 "Nuclear bodies" "Nucleoplasm, Centrosome" "HPA054451: , HPA062700: " "unprognostic (2.60e-2)" "unprognostic (5.99e-2)" "unprognostic (1.83e-2)" "unprognostic (4.85e-2)" "unprognostic (3.73e-3)" "unprognostic (1.74e-1)" "unprognostic (1.88e-1)" "unprognostic (1.58e-2)" "unprognostic (2.00e-2)" "unprognostic (6.38e-2)" "unprognostic (2.25e-3)" "unprognostic (7.41e-3)" "unprognostic (1.78e-1)" "unprognostic (4.32e-3)" "unprognostic (8.96e-3)" "unprognostic (1.65e-1)" "unprognostic (3.38e-2)" "unprognostic (1.26e-1)" "unprognostic (1.35e-2)" "unprognostic (1.40e-2)" "unprognostic (3.54e-1)" "unprognostic (1.76e-2)" "unprognostic (2.02e-2)" "unprognostic (1.84e-1)" "potential prognostic favorable (5.77e-4)" "unprognostic (9.46e-2)" "unprognostic (1.40e-1)" "unprognostic (4.07e-3)" "unprognostic (2.78e-1)" "unprognostic (8.75e-3)" "unprognostic (3.80e-2)" DHX36 "DDX36, KIAA1488, MLEL1, RHAU" ENSG00000174953 "DEAH-box helicase 36" Q9H2U1 3 154272546-154324487 "Enzymes, Essential proteins, Predicted intracellular proteins, Predicted membrane proteins" "Antiviral defense, Differentiation, Immunity, Innate immunity, Transcription, Transcription regulation, Translation regulation, Transport" "Activator, Developmental protein, DNA-binding, Helicase, Hydrolase, Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 582.9;Late spermatids: 455.4;Syncytiotrophoblasts: 426.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035399 Approved Supported Nucleoplasm,Cytosol NA NA 5000 "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 17 "Nucleoplasm, Cytosol" "HPA035399: " "unprognostic (1.33e-1)" "unprognostic (1.37e-1)" "unprognostic (1.50e-1)" "unprognostic (6.67e-3)" "unprognostic (1.10e-1)" "unprognostic (1.44e-1)" "unprognostic (7.54e-2)" "unprognostic (9.45e-2)" "unprognostic (3.13e-1)" "potential prognostic unfavorable (2.48e-4)" "potential prognostic favorable (7.62e-6)" "unprognostic (5.50e-3)" "unprognostic (1.68e-1)" "unprognostic (2.75e-2)" "unprognostic (3.79e-2)" "unprognostic (3.13e-3)" "unprognostic (4.42e-3)" "unprognostic (2.71e-1)" "unprognostic (1.96e-2)" "unprognostic (1.37e-1)" "unprognostic (3.94e-1)" "unprognostic (2.12e-2)" "potential prognostic unfavorable (6.55e-4)" "unprognostic (5.44e-2)" "unprognostic (1.02e-2)" "unprognostic (1.16e-2)" "unprognostic (1.28e-1)" "unprognostic (1.88e-1)" "unprognostic (2.69e-1)" "unprognostic (2.85e-2)" "unprognostic (7.48e-2)" DHX37 "DDX37, Dhr1, KIAA1517, MGC2695, MGC4322" ENSG00000150990 "DEAH-box helicase 37" Q8IY37 12 124946825-124989131 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Helicase, Hydrolase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047607 Approved Approved "Nuclear membrane" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 24: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 35 "Nuclear membrane" "HPA047607: " "unprognostic (1.24e-2)" "unprognostic (6.77e-2)" "unprognostic (3.41e-1)" "unprognostic (8.18e-2)" "unprognostic (2.47e-1)" "unprognostic (1.65e-2)" "unprognostic (8.06e-2)" "unprognostic (6.07e-2)" "unprognostic (2.43e-2)" "unprognostic (1.54e-2)" "unprognostic (2.56e-2)" "unprognostic (7.79e-2)" "unprognostic (1.72e-1)" "validated prognostic unfavorable (2.40e-8)" "validated prognostic unfavorable (7.09e-7)" "unprognostic (2.11e-3)" "unprognostic (4.93e-2)" "unprognostic (1.48e-1)" "unprognostic (5.06e-2)" "potential prognostic unfavorable (5.22e-4)" "unprognostic (5.21e-2)" "unprognostic (7.49e-2)" "unprognostic (3.73e-1)" "unprognostic (7.81e-2)" "unprognostic (2.86e-2)" "unprognostic (9.06e-3)" "unprognostic (4.19e-1)" "unprognostic (1.73e-1)" "unprognostic (1.42e-1)" "unprognostic (1.66e-2)" "unprognostic (2.81e-1)" DHX38 "DDX38, hPrp16, KIAA0224, PRP16, PRPF16" ENSG00000140829 "DEAH-box helicase 38" Q92620 16 72093613-72112912 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041347, HPA041604" Uncertain Supported Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 24: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 17: Non-specific - RNA processing" 35 Nucleoplasm "HPA041347: , HPA041604: " "unprognostic (6.61e-2)" "unprognostic (2.34e-1)" "unprognostic (9.26e-2)" "unprognostic (7.36e-3)" "unprognostic (2.08e-2)" "unprognostic (2.38e-1)" "unprognostic (1.64e-1)" "potential prognostic favorable (1.72e-5)" "unprognostic (7.55e-3)" "unprognostic (5.67e-2)" "unprognostic (1.49e-3)" "unprognostic (5.18e-2)" "unprognostic (2.21e-1)" "unprognostic (1.17e-3)" "unprognostic (2.12e-2)" "unprognostic (1.25e-1)" "unprognostic (3.29e-2)" "unprognostic (6.78e-2)" "unprognostic (6.70e-2)" "unprognostic (5.45e-2)" "unprognostic (5.36e-2)" "unprognostic (1.73e-2)" "potential prognostic unfavorable (3.26e-4)" "unprognostic (3.62e-3)" "unprognostic (3.67e-1)" "unprognostic (7.48e-2)" "unprognostic (4.89e-2)" "unprognostic (9.77e-2)" "unprognostic (3.26e-1)" "unprognostic (1.68e-1)" "unprognostic (2.11e-2)" DHX40 "ARG147, DDX40, FLJ22060, PAD" ENSG00000108406 "DEAH-box helicase 40" Q8IX18 17 59565558-59608345 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044350 Uncertain Approved Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 55: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 14 Nucleoplasm "HPA044350: " "unprognostic (3.33e-1)" "unprognostic (3.53e-2)" "unprognostic (3.52e-2)" "unprognostic (2.92e-1)" "unprognostic (3.28e-3)" "unprognostic (2.39e-1)" "unprognostic (4.32e-2)" "unprognostic (4.66e-1)" "unprognostic (2.73e-1)" "potential prognostic unfavorable (3.09e-4)" "potential prognostic favorable (1.69e-8)" "unprognostic (7.28e-2)" "unprognostic (2.29e-2)" "potential prognostic unfavorable (9.64e-5)" "unprognostic (1.24e-2)" "unprognostic (6.14e-2)" "unprognostic (2.10e-2)" "unprognostic (4.44e-1)" "unprognostic (3.34e-2)" "unprognostic (1.63e-1)" "unprognostic (1.54e-1)" "unprognostic (7.78e-2)" "unprognostic (3.88e-1)" "unprognostic (3.41e-1)" "unprognostic (4.37e-3)" "unprognostic (1.37e-2)" "unprognostic (1.48e-1)" "unprognostic (2.09e-1)" "unprognostic (7.52e-2)" "unprognostic (5.35e-2)" "unprognostic (9.99e-2)" DHX57 DDX57 ENSG00000163214 "DExH-box helicase 57" Q6P158 2 38797729-38875934 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 202.5;Late spermatids: 625.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036160, HPA036161" Uncertain Approved Cytosol NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 21: Testis - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 52 Cytosol "HPA036160: , HPA036161: " "unprognostic (1.06e-2)" "unprognostic (3.58e-2)" "unprognostic (8.89e-2)" "unprognostic (1.34e-2)" "unprognostic (4.58e-2)" "unprognostic (1.68e-2)" "unprognostic (7.26e-2)" "unprognostic (1.49e-2)" "unprognostic (8.53e-2)" "unprognostic (3.09e-3)" "unprognostic (4.84e-3)" "unprognostic (6.49e-2)" "unprognostic (4.35e-2)" "validated prognostic unfavorable (1.22e-4)" "validated prognostic unfavorable (3.01e-4)" "unprognostic (2.96e-1)" "unprognostic (2.51e-2)" "unprognostic (1.24e-2)" "unprognostic (4.95e-2)" "unprognostic (1.02e-1)" "unprognostic (2.02e-1)" "unprognostic (2.07e-2)" "unprognostic (1.19e-3)" "unprognostic (7.35e-2)" "unprognostic (7.96e-2)" "unprognostic (9.10e-2)" "unprognostic (1.23e-1)" "unprognostic (3.42e-1)" "unprognostic (9.45e-2)" "unprognostic (1.69e-2)" "unprognostic (7.33e-2)" DHX58 "D11LGP2, LGP2" ENSG00000108771 "DExH-box helicase 58" Q96C10 17 42101404-42112714 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 44.5;Oocytes: 32.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA018670, HPA019570" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 22 "Golgi apparatus, Cytosol" Nucleoplasm "HPA018670: , HPA019570: " "unprognostic (2.04e-1)" "unprognostic (1.47e-2)" "unprognostic (9.93e-2)" "unprognostic (2.52e-1)" "unprognostic (3.46e-2)" "unprognostic (2.35e-3)" "unprognostic (3.42e-2)" "unprognostic (2.78e-2)" "unprognostic (5.81e-2)" "unprognostic (3.31e-2)" "unprognostic (1.43e-1)" "unprognostic (6.73e-2)" "potential prognostic favorable (3.58e-4)" "unprognostic (5.14e-3)" "unprognostic (1.86e-3)" "unprognostic (1.21e-1)" "unprognostic (4.76e-1)" "unprognostic (2.18e-2)" "unprognostic (1.55e-1)" "unprognostic (5.05e-1)" "unprognostic (2.74e-1)" "unprognostic (3.92e-2)" "unprognostic (1.39e-1)" "unprognostic (3.10e-1)" "unprognostic (2.39e-1)" "unprognostic (8.93e-2)" "unprognostic (9.07e-2)" "unprognostic (7.90e-2)" "unprognostic (1.98e-2)" "unprognostic (2.13e-1)" "unprognostic (2.70e-2)" DHX8 "DDX8, Dhr2, HRH1, PRP22, PRPF22" ENSG00000067596 "DEAH-box helicase 8" Q14562 17 43483865-43610338 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049285 Approved Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 69 Nucleoplasm "Nuclear bodies" "HPA049285: " "unprognostic (4.21e-3)" "unprognostic (1.55e-1)" "unprognostic (4.69e-1)" "unprognostic (5.57e-2)" "unprognostic (2.17e-1)" "unprognostic (1.13e-3)" "unprognostic (3.80e-1)" "unprognostic (6.10e-3)" "unprognostic (3.81e-1)" "unprognostic (3.64e-2)" "unprognostic (9.19e-2)" "unprognostic (1.15e-1)" "unprognostic (2.03e-3)" "potential prognostic unfavorable (9.78e-4)" "unprognostic (1.34e-2)" "unprognostic (1.75e-2)" "unprognostic (2.32e-2)" "unprognostic (3.01e-1)" "unprognostic (6.25e-3)" "unprognostic (1.38e-2)" "unprognostic (2.47e-2)" "unprognostic (2.35e-1)" "unprognostic (2.02e-1)" "unprognostic (1.41e-1)" "unprognostic (1.01e-1)" "unprognostic (7.99e-2)" "unprognostic (2.49e-1)" "unprognostic (7.73e-2)" "unprognostic (1.90e-1)" "unprognostic (1.62e-1)" "unprognostic (1.61e-2)" DHX9 "DDX9, LKP, RHA" ENSG00000135829 "DExH-box helicase 9" Q08211 1 182839347-182887982 "Cancer-related genes, Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, DNA replication, Host-virus interaction, Immunity, Inflammatory response, Innate immunity, mRNA processing, mRNA splicing, mRNA transport, RNA-mediated gene silencing, Transcription, Transcription regulation, Transcription termination, Translation regulation, Transport" "Activator, DNA-binding, Helicase, Hydrolase, RNA-binding" "Autism spectrum disorder, Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011819, HPA028050, HPA055684" Supported Enhanced Nucleoplasm,Nucleoli NA NA 670000 "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 302 Nucleoplasm Nucleoli "CAB011819: , HPA028050: , HPA055684: " "unprognostic (4.66e-2)" "unprognostic (2.86e-2)" "unprognostic (1.44e-1)" "unprognostic (5.80e-2)" "unprognostic (2.11e-2)" "unprognostic (2.06e-1)" "unprognostic (5.09e-2)" "unprognostic (1.70e-2)" "unprognostic (1.06e-1)" "unprognostic (1.38e-2)" "potential prognostic favorable (2.14e-7)" "unprognostic (3.68e-3)" "unprognostic (7.47e-2)" "unprognostic (2.82e-2)" "unprognostic (8.12e-3)" "unprognostic (7.60e-2)" "unprognostic (1.06e-2)" "unprognostic (3.31e-1)" "unprognostic (2.63e-2)" "unprognostic (7.60e-2)" "unprognostic (1.90e-1)" "unprognostic (3.93e-3)" "unprognostic (1.17e-1)" "unprognostic (7.05e-2)" "unprognostic (3.83e-2)" "unprognostic (1.68e-1)" "unprognostic (8.67e-2)" "unprognostic (2.37e-1)" "unprognostic (2.71e-1)" "unprognostic (9.96e-2)" "unprognostic (1.57e-1)" DIABLO "DFNA64, DIABLO-S, FLJ10537, FLJ25049, SMAC" ENSG00000184047 "Diablo IAP-binding mitochondrial protein" Q9NR28 12 122207663-122227456 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 13.0;Bergmann glia: 14.4;Brain excitatory neurons: 20.6;Brain inhibitory neurons: 17.8;Choroid plexus epithelial cells: 16.2;Ependymal cells: 12.7;Microglia: 14.0;Oligodendrocyte progenitor cells: 14.9;Oligodendrocytes: 19.1;Other brain neurons: 22.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001825, CAB003857, CAB016688" Supported Supported "Mitochondria,Cytosol,Flagellar centriole,Mid piece,Principal piece,End piece" NA Yes "Cluster 33: Non-specific - ATP binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 38: Non-specific - Transcription" "Cluster 98: Neurons - Neurotransmission & signaling" 60 Mitochondria "Cytosol, Flagellar centriole, Mid piece, Principal piece, End piece" "CAB003857: , CAB016688: , HPA001825: " "unprognostic (2.35e-1)" "unprognostic (3.34e-2)" "unprognostic (7.12e-3)" "unprognostic (6.86e-3)" "unprognostic (9.47e-2)" "unprognostic (1.26e-2)" "unprognostic (2.85e-1)" "unprognostic (4.88e-2)" "unprognostic (2.13e-3)" "potential prognostic unfavorable (5.07e-4)" "potential prognostic favorable (4.99e-6)" "unprognostic (2.42e-1)" "unprognostic (1.49e-1)" "validated prognostic unfavorable (1.31e-4)" "validated prognostic unfavorable (3.81e-6)" "unprognostic (1.42e-3)" "unprognostic (2.26e-2)" "unprognostic (4.72e-2)" "unprognostic (2.51e-2)" "unprognostic (7.94e-2)" "unprognostic (2.51e-3)" "unprognostic (3.86e-2)" "unprognostic (1.67e-2)" "unprognostic (2.64e-1)" "unprognostic (1.40e-1)" "unprognostic (8.84e-2)" "unprognostic (4.16e-1)" "unprognostic (3.49e-1)" "unprognostic (1.93e-1)" "unprognostic (1.22e-1)" "unprognostic (6.17e-2)" DIAPH1 "DFNA1, hDIA1, LFHL1, mDia1" ENSG00000131504 "Diaphanous related formin 1" O60610 5 141515016-141619055 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Hearing Actin-binding "Cancer-related genes, Deafness, Disease variant, Epilepsy, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophil progenitors: 551.7;Neutrophils: 743.9;Platelets: 825.1" "Cell type enhanced" "Detected in all" "leukocyte: 378.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004916, HPA076913" Approved Uncertain "Plasma membrane,Cytosol" NA NA 1800000 "Cluster 25: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 30 "Plasma membrane, Cytosol" "HPA004916: , HPA076913: " "unprognostic (8.36e-2)" "unprognostic (1.48e-1)" "unprognostic (2.98e-1)" "unprognostic (4.11e-2)" "unprognostic (2.55e-2)" "unprognostic (1.22e-1)" "unprognostic (9.30e-2)" "unprognostic (3.94e-2)" "unprognostic (2.01e-2)" "unprognostic (9.30e-2)" "validated prognostic favorable (9.37e-7)" "validated prognostic favorable (7.10e-4)" "unprognostic (4.06e-3)" "unprognostic (2.17e-1)" "unprognostic (3.41e-2)" "unprognostic (3.72e-3)" "unprognostic (1.08e-2)" "unprognostic (8.37e-3)" "unprognostic (7.38e-2)" "unprognostic (1.84e-2)" "unprognostic (2.74e-2)" "validated prognostic unfavorable (6.07e-4)" "validated prognostic unfavorable (3.79e-4)" "unprognostic (1.21e-2)" "unprognostic (3.21e-1)" "unprognostic (6.45e-2)" "unprognostic (1.47e-1)" "unprognostic (2.56e-2)" "unprognostic (9.43e-2)" "unprognostic (1.42e-1)" "unprognostic (2.82e-2)" DIAPH2 "DIA, DIA2, POF, POF2" ENSG00000147202 "Diaphanous related formin 2" O60879 X 96684712-97604997 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Oogenesis" "Developmental protein" "Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Choroid plexus epithelial cells: 1354.9;Microglia: 1164.1;Myonuclei: 1100.6;Neutrophil progenitors: 1785.7;Sertoli cells: 1959.1;Syncytiotrophoblasts: 1294.5" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 1427.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells, Lung - Fibroblasts_1, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005647, CAB015461, CAB068183, CAB068184" Enhanced Supported "Nucleoli,Endoplasmic reticulum,Vesicles" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 8 "Endoplasmic reticulum, Vesicles" Nucleoli "CAB015461: , CAB068183: , CAB068184: , HPA005647: " "unprognostic (1.52e-1)" "unprognostic (1.28e-1)" "unprognostic (1.49e-1)" "unprognostic (2.50e-3)" "unprognostic (2.03e-1)" "unprognostic (4.43e-1)" "unprognostic (3.37e-1)" "unprognostic (6.81e-2)" "unprognostic (1.23e-2)" "unprognostic (8.22e-2)" "potential prognostic favorable (1.40e-4)" "unprognostic (5.71e-2)" "unprognostic (1.19e-2)" "unprognostic (1.48e-1)" "unprognostic (1.23e-1)" "unprognostic (1.28e-1)" "unprognostic (1.58e-1)" "unprognostic (4.96e-2)" "unprognostic (1.90e-1)" "unprognostic (1.89e-1)" "unprognostic (4.01e-2)" "unprognostic (7.44e-3)" "unprognostic (4.67e-2)" "unprognostic (3.91e-2)" "unprognostic (1.66e-2)" "unprognostic (6.85e-2)" "unprognostic (2.84e-1)" "unprognostic (4.74e-2)" "unprognostic (3.36e-2)" "potential prognostic unfavorable (3.89e-4)" "unprognostic (3.48e-2)" DIAPH3 "AN, AUNA1, DRF3, FLJ34705, NSDAN" ENSG00000139734 "Diaphanous related formin 3" Q9NSV4 13 59665583-60163928 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Deafness, Neuropathy, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.7;testis: 17.7" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 135.7;Early spermatids: 534.8;Erythrocyte progenitors: 291.6;Extravillous trophoblasts: 183.3;Late primary spermatocytes: 390.1;Megakaryocyte progenitors: 150.9;Mesothelial cells: 200.1;Migrating cytotrophoblasts: 152.9;Monocyte progenitors: 230.4;Neutrophil progenitors: 186.1;Parietal cells: 281.1" "Cell type enhanced" "Detected in many" "ependymal cell: 105.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Spleen - Mitotic cells (Spleen), Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032151 Supported "Plasma membrane,Microtubules" NA Yes "Cluster 39: Testis - Nuclear processes" "Cluster 19: Non-specific - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 8 "Plasma membrane, Microtubules" "HPA032151: " "unprognostic (5.77e-2)" "unprognostic (1.35e-1)" "unprognostic (1.43e-2)" "potential prognostic unfavorable (3.05e-4)" "unprognostic (4.93e-2)" "unprognostic (6.59e-2)" "unprognostic (3.94e-1)" "unprognostic (3.46e-1)" "unprognostic (5.85e-2)" "potential prognostic unfavorable (7.37e-5)" "unprognostic (4.00e-3)" "unprognostic (3.67e-2)" "unprognostic (2.30e-2)" "potential prognostic unfavorable (1.52e-7)" "validated prognostic unfavorable (6.38e-5)" "validated prognostic unfavorable (6.75e-5)" "unprognostic (2.16e-1)" "unprognostic (1.47e-1)" "unprognostic (3.43e-2)" "unprognostic (2.53e-1)" "potential prognostic unfavorable (6.87e-5)" "unprognostic (8.11e-3)" "unprognostic (1.58e-2)" "unprognostic (4.29e-3)" "unprognostic (4.30e-2)" "unprognostic (1.21e-1)" "unprognostic (1.65e-1)" "unprognostic (4.65e-2)" DICER1 "Dicer, HERNA, K12H4.8-LIKE, KIAA0928, MNG1" ENSG00000100697 "Dicer 1, ribonuclease III" Q9UPY3 14 95086228-95158010 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction, RNA-mediated gene silencing" "Endonuclease, Helicase, Hydrolase, Nuclease, RNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 455.8;Oligodendrocytes: 444.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000694, CAB068185" Approved Supported Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 24: Neutrophils - Innate immunity signal integration" 62 Cytosol "CAB068185: , HPA000694: " "unprognostic (1.34e-2)" "unprognostic (2.80e-1)" "unprognostic (4.03e-1)" "unprognostic (2.16e-2)" "unprognostic (1.60e-1)" "unprognostic (2.25e-1)" "unprognostic (4.73e-2)" "unprognostic (2.61e-2)" "unprognostic (6.65e-2)" "unprognostic (1.27e-1)" "potential prognostic favorable (1.03e-5)" "unprognostic (4.43e-3)" "unprognostic (3.06e-1)" "unprognostic (3.37e-2)" "unprognostic (1.61e-2)" "unprognostic (2.01e-1)" "unprognostic (1.17e-1)" "unprognostic (1.55e-1)" "unprognostic (3.03e-1)" "unprognostic (6.39e-2)" "unprognostic (3.16e-2)" "unprognostic (1.17e-1)" "unprognostic (4.86e-3)" "unprognostic (3.35e-1)" "unprognostic (1.12e-1)" "unprognostic (2.64e-2)" "unprognostic (2.75e-1)" "unprognostic (1.81e-1)" "unprognostic (3.57e-1)" "unprognostic (1.14e-2)" "unprognostic (6.12e-2)" DIDO1 "BYE1, C20orf158, DATF1, DIO-1, DIO1, dJ885L7.8, FLJ11265, KIAA0333" ENSG00000101191 "Death inducer-obliterator 1" Q9BTC0 20 62877738-62937952 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004374, HPA049904" Supported Approved Nucleoplasm,Vesicles,Cytosol No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 49: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 62: Non-specific - Plasma proteins" "Cluster 7: Non-specific - Transcription" 42 Nucleoplasm "Vesicles, Cytosol" "CAB004374: , HPA049904: " "potential prognostic favorable (6.81e-4)" "unprognostic (3.35e-3)" "unprognostic (3.23e-1)" "unprognostic (1.25e-2)" "unprognostic (5.57e-2)" "unprognostic (1.73e-1)" "unprognostic (4.00e-1)" "unprognostic (4.78e-2)" "unprognostic (7.52e-3)" "unprognostic (3.45e-2)" "unprognostic (2.64e-3)" "unprognostic (3.77e-1)" "unprognostic (2.36e-2)" "unprognostic (1.48e-3)" "unprognostic (2.16e-1)" "unprognostic (9.45e-3)" "unprognostic (4.26e-2)" "unprognostic (2.33e-1)" "unprognostic (7.71e-2)" "unprognostic (4.52e-1)" "unprognostic (1.26e-1)" "unprognostic (3.29e-2)" "unprognostic (5.10e-3)" "unprognostic (1.02e-1)" "unprognostic (1.89e-3)" "unprognostic (2.45e-3)" "unprognostic (1.63e-2)" "unprognostic (2.74e-1)" "unprognostic (1.57e-1)" "unprognostic (1.56e-1)" "unprognostic (2.82e-1)" DIMT1 "DIMT1L, HSA9761" ENSG00000086189 "DIM1 rRNA methyltransferase and ribosome maturation factor" Q9UNQ2 5 62347284-62403943 "Enzymes, Essential proteins, Predicted intracellular proteins" "rRNA processing" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042944 Approved Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 27: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 17: Non-specific - RNA processing" 42 "Nucleoli, Nucleoli rim" "Nucleoplasm, Cytosol" "HPA042944: " "unprognostic (1.99e-2)" "unprognostic (4.90e-2)" "unprognostic (1.13e-1)" "unprognostic (7.71e-2)" "unprognostic (1.29e-1)" "unprognostic (6.41e-2)" "unprognostic (9.84e-3)" "unprognostic (2.51e-2)" "unprognostic (3.26e-3)" "unprognostic (2.32e-2)" "unprognostic (5.08e-1)" "unprognostic (1.16e-1)" "potential prognostic unfavorable (2.47e-4)" "unprognostic (1.96e-3)" "unprognostic (2.13e-2)" "unprognostic (3.06e-2)" "unprognostic (1.16e-1)" "unprognostic (2.30e-1)" "unprognostic (9.51e-3)" "unprognostic (2.56e-2)" "unprognostic (3.68e-1)" "unprognostic (1.04e-1)" "unprognostic (1.02e-1)" "unprognostic (4.62e-2)" "unprognostic (2.57e-1)" "unprognostic (1.19e-1)" "unprognostic (3.55e-1)" "unprognostic (1.10e-1)" "unprognostic (5.86e-2)" DIO1 TXDI1 ENSG00000211452 "Iodothyronine deiodinase 1" P49895 1 53891239-53911086 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Thyroid hormones biosynthesis" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 42 "kidney: 135.2;liver: 173.3;thyroid gland: 243.4" "Group enriched" "Detected in many" 4 "Hepatocytes: 78.1;Proximal tubule cells: 81.2" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 7 "Liver Hepatocellular Carcinoma (TCGA): 70.8;Thyroid Carcinoma (TCGA): 85.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "breast cancer: 3.8;liver cancer: 2.5;prostate cancer: 4.9;thyroid cancer: 9.2" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 16: Liver & Kidney - Metabolism" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 88: Proximal tubular cells - Transmembrane transport" "unprognostic (2.06e-2)" "unprognostic (2.53e-2)" "unprognostic (1.54e-1)" "unprognostic (1.87e-1)" "unprognostic (2.35e-1)" "unprognostic (2.44e-3)" "unprognostic (7.60e-2)" "potential prognostic favorable (3.86e-4)" "unprognostic (1.88e-1)" "unprognostic (2.96e-1)" "unprognostic (1.93e-1)" "potential prognostic unfavorable (4.51e-4)" DIO2 "SELENOY, SelY, TXDI2" ENSG00000211448 "Iodothyronine deiodinase 2" Q92813 14 80197526-80387757 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Thyroid hormones biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 153.7;thyroid gland: 332.6" "Group enriched" "Detected in many" 4 "Esophageal apical cells: 2054.0;Extravillous trophoblasts: 1049.8" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Thyroid Carcinoma (TCGA): 85.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder cancer: 95.8;Brain cancer: 82.1" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells, Pituitary gland - Thyrotropes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048002 Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 33: Thyroid gland - Tissue development" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 4 "Nucleoplasm, Vesicles" "Plasma membrane" "HPA048002: " "unprognostic (7.95e-3)" "unprognostic (1.93e-1)" "unprognostic (1.15e-1)" "unprognostic (1.40e-1)" "unprognostic (9.24e-2)" "unprognostic (7.22e-2)" "unprognostic (2.69e-1)" "potential prognostic unfavorable (3.69e-4)" "unprognostic (1.76e-1)" "unprognostic (1.07e-1)" "unprognostic (7.20e-2)" "unprognostic (1.70e-1)" "unprognostic (5.99e-2)" "unprognostic (4.05e-1)" "unprognostic (1.40e-2)" "unprognostic (3.26e-2)" "unprognostic (3.28e-1)" "unprognostic (1.91e-2)" "unprognostic (1.44e-1)" "unprognostic (4.29e-2)" "unprognostic (5.17e-3)" "unprognostic (5.61e-2)" "unprognostic (1.42e-1)" "unprognostic (3.01e-1)" "unprognostic (1.44e-1)" "unprognostic (4.87e-2)" "unprognostic (2.03e-1)" "unprognostic (5.28e-2)" "unprognostic (1.46e-1)" "unprognostic (2.08e-2)" "unprognostic (2.32e-1)" DIO3 TXDI3 ENSG00000197406 "Iodothyronine deiodinase 3" P55073 14 101560139-101563452 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Thyroid hormones biosynthesis" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 20.8;placenta: 18.3" "Group enriched" "Detected in some" 5 "Adipocytes: 46.7;Fibroblasts: 28.8;Syncytiotrophoblasts: 104.4" "Cell type enriched" "Detected in single" 4 "pericyte: 3.1" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 8.4" "Region enhanced" "Detected in some" "thalamus: 7.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 8.1" "Thyroid gland - Macrophages" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "amygdala: 6.1;hippocampal formation: 7.7" HPA073684 Supported Vesicles NA NA "Cluster 75: Ovary - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 108: Fibroblasts - ECM organization" 12 Vesicles "HPA073684: " "unprognostic (5.51e-2)" "unprognostic (4.83e-3)" "unprognostic (1.15e-2)" "unprognostic (6.95e-3)" "unprognostic (2.44e-1)" "unprognostic (1.53e-1)" "unprognostic (1.98e-1)" "unprognostic (9.77e-2)" "potential prognostic favorable (8.86e-4)" "unprognostic (1.16e-1)" "unprognostic (1.99e-2)" "unprognostic (8.93e-2)" DIP2A "C21orf106, Dip2, KIAA0184" ENSG00000160305 "Disco interacting protein 2 homolog A" Q14689 21 46458891-46570015 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Neurogenesis "Developmental protein, Ligase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglia: 322.1;Neutrophil progenitors: 297.7;NK-cells: 279.2;Rod photoreceptor cells: 396.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044692, HPA052516" Uncertain Uncertain "Nucleoplasm,Plasma membrane,Actin filaments,Focal adhesion sites,Mitochondria" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 6: Non-specific - Immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 8 Nucleoplasm "Plasma membrane, Actin filaments, Focal adhesion sites, Mitochondria" "HPA044692: , HPA052516: " "unprognostic (1.00e-1)" "unprognostic (1.41e-2)" "unprognostic (1.40e-2)" "unprognostic (7.64e-3)" "unprognostic (2.27e-1)" "unprognostic (1.48e-1)" "unprognostic (2.48e-1)" "unprognostic (8.14e-3)" "unprognostic (8.87e-3)" "unprognostic (3.41e-2)" "potential prognostic favorable (1.05e-5)" "unprognostic (7.86e-3)" "unprognostic (1.80e-1)" "unprognostic (1.72e-1)" "unprognostic (1.84e-1)" "unprognostic (5.90e-2)" "unprognostic (7.41e-2)" "unprognostic (3.37e-1)" "unprognostic (6.43e-2)" "unprognostic (3.16e-3)" "unprognostic (4.86e-2)" "unprognostic (2.20e-1)" "unprognostic (3.67e-3)" "unprognostic (1.58e-1)" "unprognostic (7.25e-2)" "unprognostic (1.48e-1)" "unprognostic (1.27e-1)" "unprognostic (2.15e-1)" "unprognostic (2.03e-1)" "unprognostic (6.30e-2)" "unprognostic (8.83e-2)" DIP2B "FLJ34278, KIAA1463" ENSG00000066084 "Disco interacting protein 2 homolog B" Q9P265 12 50504985-50748657 "Human disease related genes, Predicted intracellular proteins" Neurogenesis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglia: 778.7;Neutrophils: 1190.2;Ocular epithelial cells: 658.0;Oligodendrocytes: 1072.9" "Cell type enhanced" "Detected in all" "oligodendrocyte: 1310.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038472, HPA046133, HPA056045" Enhanced Approved "Endoplasmic reticulum" No No "Cluster 20: Non-specific - DNA binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 24: Neutrophils - Innate immunity signal integration" 3 "Endoplasmic reticulum" "HPA038472: , HPA046133: , HPA056045: " "unprognostic (1.56e-3)" "unprognostic (2.71e-3)" "unprognostic (4.06e-1)" "unprognostic (5.83e-2)" "unprognostic (3.39e-2)" "unprognostic (4.78e-2)" "unprognostic (7.28e-2)" "unprognostic (7.64e-3)" "unprognostic (1.73e-1)" "potential prognostic unfavorable (3.81e-4)" "potential prognostic favorable (1.13e-5)" "unprognostic (9.05e-3)" "unprognostic (1.75e-1)" "unprognostic (2.72e-2)" "unprognostic (2.05e-2)" "unprognostic (5.91e-3)" "unprognostic (9.82e-3)" "unprognostic (1.38e-3)" "unprognostic (1.04e-1)" "unprognostic (6.46e-2)" "unprognostic (4.41e-2)" "unprognostic (1.41e-2)" "potential prognostic unfavorable (8.95e-5)" "unprognostic (7.74e-2)" "unprognostic (1.26e-1)" "unprognostic (1.92e-2)" "unprognostic (2.96e-2)" "unprognostic (1.39e-2)" "unprognostic (1.05e-1)" "unprognostic (1.74e-2)" "unprognostic (2.26e-1)" DIP2C KIAA0934 ENSG00000151240 "Disco interacting protein 2 homolog C" Q9Y2E4 10 274190-689668 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 734.7;Proximal tubule cells: 742.6;Renal collecting duct intercalated cells: 796.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030264, HPA059325" Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 58: Mast cells - Allergic inflammatory responses" Nucleoplasm "Vesicles, Cytosol" "HPA030264: , HPA059325: " "unprognostic (5.61e-3)" "unprognostic (4.66e-2)" "unprognostic (2.99e-1)" "unprognostic (2.94e-2)" "unprognostic (1.37e-1)" "unprognostic (1.41e-1)" "unprognostic (1.42e-1)" "potential prognostic favorable (3.09e-5)" "unprognostic (2.51e-1)" "unprognostic (1.68e-1)" "potential prognostic favorable (4.67e-10)" "unprognostic (3.93e-2)" "unprognostic (9.45e-3)" "unprognostic (3.17e-2)" "unprognostic (8.65e-2)" "unprognostic (2.50e-1)" "unprognostic (1.66e-1)" "unprognostic (4.63e-2)" "unprognostic (3.02e-1)" "unprognostic (1.26e-2)" "unprognostic (1.11e-2)" "unprognostic (2.64e-1)" "unprognostic (5.41e-2)" "unprognostic (1.28e-2)" "unprognostic (6.48e-2)" "unprognostic (6.33e-3)" "unprognostic (1.67e-1)" "unprognostic (2.63e-2)" "unprognostic (9.70e-2)" "unprognostic (6.42e-3)" "unprognostic (8.00e-2)" DIPK1A "FAM69A, FLJ23493" ENSG00000154511 "Divergent protein kinase domain 1A" Q5T7M9 1 92832737-92961522 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 245.4;Epicardial cells: 263.8;Mesothelial cells: 270.4;Oligodendrocytes: 237.5;Plasma cells: 288.0;Sertoli cells: 269.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 81.6" "Liver - Hepatocytes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015718, HPA017281" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 36: Brain & Liver - Signaling" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 87: B-cells - Adaptive immunity: Humoral response" Cytosol Nucleoplasm "HPA015718: , HPA017281: " "unprognostic (3.22e-1)" "unprognostic (2.26e-3)" "unprognostic (4.94e-2)" "unprognostic (1.33e-3)" "unprognostic (3.26e-2)" "unprognostic (3.23e-2)" "unprognostic (2.43e-1)" "unprognostic (3.77e-2)" "unprognostic (4.61e-2)" "unprognostic (5.71e-2)" "unprognostic (3.09e-1)" "potential prognostic unfavorable (8.64e-4)" "unprognostic (1.41e-2)" "unprognostic (1.69e-2)" "unprognostic (4.39e-1)" "unprognostic (3.75e-1)" "unprognostic (2.86e-1)" "unprognostic (1.57e-2)" "unprognostic (6.96e-2)" "unprognostic (2.59e-1)" "unprognostic (2.26e-3)" "unprognostic (4.61e-2)" "unprognostic (1.34e-1)" "unprognostic (1.18e-1)" "unprognostic (2.14e-1)" "unprognostic (9.19e-3)" "unprognostic (1.94e-1)" "unprognostic (6.36e-2)" "unprognostic (1.63e-2)" DIPK1B "C9orf136, FAM69B, MGC20262" ENSG00000165716 "Divergent protein kinase domain 1B" Q5VUD6 9 136712572-136724742 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hematopoietic stem cells: 57.7;Megakaryocyte progenitors: 44.8;Megakaryocyte-Erythroid progenitors: 54.3;Megakaryocytes: 74.2;Melanocytes: 33.3;Platelets: 126.9;Retinal horizontal cells: 36.1;Vascular endothelial cells: 48.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "memory B-cell: 1.0;naive B-cell: 2.8;plasmacytoid DC: 1.0" "Group enriched" "Detected in many" 9 "B-cells: 2.8;dendritic cells: 1.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054443 Approved "Nucleoplasm,Nuclear bodies,Vesicles" No No "Cluster 34: B-cells - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 35: RS4;11 - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 1 "Nuclear bodies" "Nucleoplasm, Vesicles" "HPA054443: " "unprognostic (2.98e-2)" "unprognostic (7.54e-2)" "unprognostic (1.22e-2)" "unprognostic (3.66e-3)" "unprognostic (2.60e-1)" "unprognostic (1.60e-1)" "unprognostic (1.02e-2)" "unprognostic (3.40e-2)" "unprognostic (3.03e-1)" "unprognostic (2.37e-2)" "unprognostic (1.06e-2)" "unprognostic (3.74e-1)" "unprognostic (2.50e-1)" "unprognostic (1.08e-1)" "unprognostic (2.73e-1)" "unprognostic (2.90e-1)" "unprognostic (2.40e-3)" "unprognostic (5.93e-2)" "unprognostic (1.23e-1)" "potential prognostic favorable (5.13e-5)" "unprognostic (8.84e-2)" "unprognostic (1.88e-1)" "unprognostic (1.49e-1)" "unprognostic (1.06e-1)" "unprognostic (3.90e-1)" "unprognostic (4.84e-2)" "unprognostic (2.95e-2)" "unprognostic (1.75e-1)" "unprognostic (7.76e-2)" DIPK1C "C18orf51, FAM69C" ENSG00000187773 "Divergent protein kinase domain 1C" Q0P6D2 18 74434775-74457944 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 36.3;retina: 15.3" "Cell type enriched" "Detected in some" 4 "Müller glia: 219.4" "Group enriched" "Detected in many" 6 "astrocyte: 42.2;Bergmann glia: 14.1;committed oligodendrocyte precursor: 28.5;oligodendrocyte: 42.4;oligodendrocyte precursor cell: 29.0;pericyte: 13.7" "Group enriched" "Detected in some" 21 "Glioblastoma Multiforme (TCGA): 35.2;Skin Cutaneous Melanoma (TCGA): 18.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "Leukemia: 2.5;skin cancer: 3.5" "Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048928 Enhanced NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 11: Muller glia cells - Retinal homeostasis" "HPA048928: " "unprognostic (3.28e-2)" "unprognostic (2.24e-3)" "unprognostic (3.90e-3)" "unprognostic (5.20e-2)" "unprognostic (1.41e-1)" "potential prognostic favorable (2.35e-5)" "unprognostic (8.79e-2)" DIPK2A "C3orf58, DIA1, HASF, MGC33365" ENSG00000181744 "Divergent protein kinase domain 2A" Q8NDZ4 3 143971823-144048719 "Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bergmann glia: 263.2;Ependymal cells: 173.1;Oligodendrocytes: 156.4;pDCs: 171.5" "Cell type enhanced" "Detected in all" "Bergmann glia: 285.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048992 Approved "Secreted in other tissues" "No annotated function" NA NA 20000 "Cluster 41: Basophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 20: Non-specific - Transcription regulation" 18 "HPA048992: " "unprognostic (3.59e-2)" "unprognostic (2.29e-1)" "unprognostic (3.89e-1)" "unprognostic (1.12e-1)" "unprognostic (1.70e-1)" "unprognostic (1.27e-1)" "unprognostic (3.54e-1)" "unprognostic (7.71e-2)" "unprognostic (1.71e-2)" "unprognostic (2.29e-3)" "unprognostic (7.98e-2)" "unprognostic (2.01e-3)" "unprognostic (2.72e-2)" "unprognostic (8.10e-2)" "unprognostic (2.22e-1)" "potential prognostic favorable (9.15e-4)" "unprognostic (2.84e-2)" "unprognostic (2.21e-2)" "unprognostic (1.68e-1)" "unprognostic (3.01e-1)" "unprognostic (2.57e-1)" "unprognostic (3.52e-1)" "unprognostic (1.54e-1)" "unprognostic (1.32e-2)" "unprognostic (1.03e-1)" "unprognostic (5.31e-2)" "unprognostic (2.46e-1)" "unprognostic (2.14e-1)" "unprognostic (9.59e-2)" DIPK2B "CXorf36, DIA1R, FLJ14103" ENSG00000147113 "Divergent protein kinase domain 2B" Q9H7Y0 X 45148373-45200901 "Disease related genes, Predicted secreted proteins" "Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 8 "Lymphatic endothelial cells: 248.1;Vascular endothelial cells: 279.9" "Cell type enriched" "Detected in some" 9 "endothelial cell: 406.1" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 27.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Pancreas - Endothelial cells, Pituitary gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid gland - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA002806 Uncertain "Secreted - unknown location" "No annotated function" NA NA 680000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 6: Non-specific - Immune response" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "HPA002806: " "unprognostic (7.89e-2)" "unprognostic (1.57e-1)" "unprognostic (2.84e-1)" "unprognostic (4.03e-2)" "unprognostic (2.92e-1)" "unprognostic (2.32e-1)" "unprognostic (8.00e-2)" "unprognostic (2.20e-2)" "unprognostic (9.74e-2)" "validated prognostic favorable (5.39e-6)" "validated prognostic favorable (3.23e-4)" "potential prognostic unfavorable (5.59e-4)" "unprognostic (6.31e-2)" "unprognostic (1.09e-1)" "unprognostic (3.51e-2)" "unprognostic (8.37e-3)" "unprognostic (2.97e-1)" "unprognostic (2.61e-1)" "unprognostic (1.04e-1)" "unprognostic (4.94e-2)" "unprognostic (3.02e-1)" "unprognostic (3.83e-2)" "unprognostic (7.49e-3)" "unprognostic (1.17e-1)" "unprognostic (2.12e-1)" "unprognostic (4.51e-3)" "unprognostic (6.80e-2)" "unprognostic (9.17e-2)" "unprognostic (1.48e-2)" DIRAS1 "Di-Ras1, GBTS1, RIG" ENSG00000176490 "DIRAS family GTPase 1" O95057 19 2714567-2721372 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 90.2;heart muscle: 98.9;tongue: 48.4" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 20.8;Brain inhibitory neurons: 20.1;Gonadotrophs: 12.7;Hofbauer cells: 10.6;Lactotrophs: 11.8;Other brain neurons: 13.9;Retinal amacrine cells: 33.3;Retinal horizontal cells: 38.1;Smooth muscle cells: 12.7" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 29.9;Skin Cutaneous Melanoma (TCGA): 25.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Lactotropes, Prostate - Smooth muscle cells, Spleen - B-cells (Spleen), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050164 Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 6: Leukemia - Signal transduction" "Cluster 109: Neurons - Neuronal signaling" 9 "Vesicles, Plasma membrane" Nucleoplasm "HPA050164: " "unprognostic (1.26e-3)" "unprognostic (2.32e-1)" "unprognostic (3.44e-2)" "unprognostic (1.24e-2)" "unprognostic (2.31e-1)" "unprognostic (4.57e-2)" "unprognostic (1.58e-3)" "unprognostic (1.99e-1)" "unprognostic (8.23e-2)" "unprognostic (1.55e-2)" "unprognostic (3.63e-2)" "unprognostic (4.77e-3)" "unprognostic (2.95e-2)" "unprognostic (4.37e-2)" "potential prognostic favorable (5.31e-4)" "unprognostic (2.12e-1)" "unprognostic (1.40e-1)" "unprognostic (1.81e-1)" "unprognostic (1.61e-2)" "unprognostic (5.17e-2)" "unprognostic (8.38e-2)" DIRAS2 "Di-Ras2, DKFZp761C07121" ENSG00000165023 "DIRAS family GTPase 2" Q96HU8 9 90609832-90642862 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 152.2" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 112.6;Brain inhibitory neurons: 45.5;Breast lactating cells: 30.4;Other brain neurons: 53.3;Retinal amacrine cells: 91.0;Retinal bipolar cells: 126.1;Retinal horizontal cells: 66.1;Rod photoreceptor cells: 46.0" "Cell type enhanced" "Detected in all" "deep-layer corticothalamic and 6b: 265.0;deep-layer near-projecting: 412.1" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 13.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 10.8;Rhabdoid: 8.5" "Adrenal gland - Adrenal medulla cells, Minor Salivary Gland - Minor salivary glandular cells, Stomach - Gastric enteroendocrine cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 34: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 5 "unprognostic (2.00e-3)" "unprognostic (1.94e-2)" "unprognostic (7.49e-2)" "unprognostic (2.18e-2)" "unprognostic (8.85e-2)" "unprognostic (9.06e-3)" "unprognostic (1.92e-1)" "validated prognostic favorable (4.53e-7)" "validated prognostic favorable (1.73e-4)" "unprognostic (1.70e-1)" "unprognostic (6.36e-2)" "unprognostic (1.05e-1)" "unprognostic (3.00e-1)" "unprognostic (7.98e-2)" "unprognostic (1.44e-1)" "unprognostic (6.29e-3)" "unprognostic (9.69e-2)" "unprognostic (7.60e-2)" "unprognostic (1.53e-1)" "unprognostic (2.27e-1)" "unprognostic (3.56e-3)" "unprognostic (2.92e-2)" DIRAS3 "ARHI, NOEY2" ENSG00000162595 "DIRAS family GTPase 3" O95661 1 68045886-68051717 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 184.1;ovary: 49.8;pituitary gland: 65.9" "Cell type enhanced" "Detected in many" "Corticotrophs: 28.0;Epididymal basal cells: 47.8;Gonadotrophs: 63.8;Neuroendocrine cells: 39.4;Oocytes: 27.6;Other brain neurons: 118.1;Ovarian stromal cells: 84.2;Pancreatic acinar cells: 36.6;Pancreatic islet cells: 32.3;Somatotrophs: 31.3" "Cell type enhanced" "Detected in many" "eccentric medium spiny neuron: 79.4" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 35.0;Thyroid Carcinoma (TCGA): 27.3" "Region enhanced" "Detected in all" "hypothalamus: 303.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Brain cancer: 37.8;Rhabdoid: 28.0" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "HPA028483, HPA028557, HPA029384" Approved Approved "Nuclear membrane,Cytosol" NA NA "Cluster 65: Brain - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 72: Neuronal - Signal transduction" "Cluster 98: Neurons - Neurotransmission & signaling" 5 "Nuclear membrane, Cytosol" "HPA028483: , HPA028557: , HPA029384: " "unprognostic (3.89e-2)" "unprognostic (1.41e-3)" "unprognostic (1.72e-2)" "unprognostic (2.71e-3)" "unprognostic (2.12e-2)" "unprognostic (1.09e-2)" "potential prognostic unfavorable (3.70e-4)" "unprognostic (1.37e-1)" "unprognostic (4.46e-2)" "unprognostic (7.86e-2)" "unprognostic (9.00e-2)" "potential prognostic favorable (2.55e-5)" "unprognostic (7.22e-2)" "unprognostic (2.69e-3)" "unprognostic (2.44e-1)" "unprognostic (9.87e-2)" "unprognostic (2.03e-2)" "unprognostic (5.23e-1)" "unprognostic (9.36e-2)" "unprognostic (1.58e-2)" "unprognostic (2.44e-2)" "unprognostic (1.05e-1)" "unprognostic (3.50e-1)" "unprognostic (1.64e-2)" "unprognostic (2.05e-1)" "unprognostic (1.92e-1)" "unprognostic (2.60e-2)" "unprognostic (1.57e-1)" DIS3 "dis3p, EXOSC11, KIAA1008, RRP44" ENSG00000083520 "DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease" Q9Y2L1 13 72752169-72782096 "Cancer-related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "rRNA processing" "Endonuclease, Exonuclease, Hydrolase, Nuclease, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 165.4;Late spermatids: 222.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039281, HPA058762" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 19: Non-specific - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 46 Nucleoplasm Cytosol "HPA039281: , HPA058762: " "unprognostic (1.99e-2)" "unprognostic (5.30e-3)" "unprognostic (1.04e-1)" "unprognostic (4.47e-2)" "unprognostic (1.09e-1)" "unprognostic (8.15e-3)" "unprognostic (1.33e-1)" "unprognostic (1.32e-1)" "unprognostic (1.38e-2)" "unprognostic (6.26e-3)" "potential prognostic favorable (1.15e-5)" "unprognostic (1.84e-3)" "unprognostic (3.11e-1)" "unprognostic (1.11e-1)" "unprognostic (1.71e-1)" "unprognostic (1.53e-2)" "unprognostic (2.19e-3)" "unprognostic (9.49e-2)" "unprognostic (2.75e-3)" "unprognostic (1.56e-1)" "unprognostic (6.11e-2)" "unprognostic (1.52e-3)" "unprognostic (1.52e-2)" "unprognostic (7.00e-3)" "unprognostic (6.59e-3)" "unprognostic (1.36e-1)" "unprognostic (1.47e-2)" "unprognostic (5.22e-2)" "unprognostic (2.42e-1)" "unprognostic (2.57e-2)" "unprognostic (6.90e-2)" DIS3L "DIS3L1, FLJ38088, KIAA1955, MGC4562" ENSG00000166938 "DIS3 like exosome 3'-5' exoribonuclease" Q8TF46 15 66293217-66333898 "Predicted intracellular proteins" "Exonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040475, HPA041805" Approved Supported "Plasma membrane,Centrosome,Basal body,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 33 "Centrosome, Basal body, Cytosol" "Plasma membrane" "HPA040475: , HPA041805: " "unprognostic (1.51e-1)" "unprognostic (4.76e-2)" "unprognostic (3.63e-1)" "unprognostic (1.45e-1)" "unprognostic (7.12e-2)" "unprognostic (2.40e-1)" "unprognostic (3.73e-1)" "unprognostic (2.64e-1)" "unprognostic (2.90e-1)" "unprognostic (1.74e-2)" "unprognostic (4.79e-3)" "unprognostic (2.29e-3)" "unprognostic (3.85e-2)" "unprognostic (1.66e-1)" "unprognostic (3.39e-2)" "unprognostic (1.35e-2)" "unprognostic (1.83e-1)" "unprognostic (1.37e-1)" "unprognostic (5.37e-2)" "unprognostic (6.15e-3)" "unprognostic (2.65e-1)" "unprognostic (2.47e-3)" "unprognostic (1.76e-1)" "unprognostic (3.13e-1)" "unprognostic (4.86e-2)" "unprognostic (3.02e-1)" "unprognostic (9.24e-2)" "unprognostic (1.51e-1)" "unprognostic (1.59e-1)" "unprognostic (2.50e-1)" "unprognostic (1.20e-1)" DIS3L2 "FAM6A, FLJ36974, MGC42174" ENSG00000144535 "DIS3 like 3'-5' exoribonuclease 2" Q8IYB7 2 231961245-232344350 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Exonuclease, Hydrolase, Nuclease, RNA-binding" "Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035796, HPA035797" Approved NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 64: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 7: Non-specific - Transcription" 3 "HPA035796: , HPA035797: " "unprognostic (2.07e-1)" "unprognostic (2.41e-1)" "unprognostic (1.37e-1)" "unprognostic (1.86e-3)" "unprognostic (1.08e-1)" "unprognostic (2.29e-2)" "unprognostic (3.04e-1)" "unprognostic (1.62e-1)" "unprognostic (7.50e-2)" "unprognostic (2.32e-1)" "unprognostic (9.17e-2)" "unprognostic (3.01e-2)" "potential prognostic favorable (1.97e-4)" "unprognostic (2.28e-3)" "unprognostic (6.57e-2)" "unprognostic (9.37e-2)" "unprognostic (3.43e-2)" "unprognostic (2.42e-1)" "unprognostic (3.06e-2)" "unprognostic (3.88e-1)" "unprognostic (6.82e-2)" "unprognostic (1.26e-1)" "unprognostic (1.71e-3)" "unprognostic (2.52e-2)" "unprognostic (2.24e-2)" "potential prognostic favorable (6.35e-4)" "unprognostic (2.81e-1)" "unprognostic (1.42e-1)" "unprognostic (2.57e-2)" "unprognostic (4.36e-2)" "unprognostic (9.08e-2)" DISC1 ENSG00000162946 "DISC1 scaffold protein" Q9NRI5 1 231626790-232041272 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Neurogenesis, Wnt signaling pathway" "Developmental protein" Schizophrenia "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 20.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 3199.9;Microglia: 1143.7;Neutrophils: 600.1;Oligodendrocyte progenitor cells: 792.5;Rod photoreceptor cells: 866.5" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 1466.3;oligodendrocyte precursor cell: 865.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Testis - Early spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA048911 Supported "Intermediate filaments,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 178 "Intermediate filaments, Cytosol" "HPA048911: " "unprognostic (1.55e-3)" "unprognostic (2.27e-1)" "unprognostic (1.70e-1)" "unprognostic (1.90e-1)" "unprognostic (8.78e-2)" "unprognostic (1.04e-1)" "unprognostic (5.60e-2)" "unprognostic (9.60e-2)" "unprognostic (8.83e-2)" "potential prognostic favorable (9.81e-5)" "unprognostic (1.79e-3)" "unprognostic (1.24e-1)" "unprognostic (2.15e-2)" "unprognostic (7.93e-2)" "unprognostic (4.18e-2)" "unprognostic (1.30e-1)" "unprognostic (4.13e-2)" "unprognostic (1.41e-1)" "unprognostic (3.31e-1)" "unprognostic (2.15e-1)" "unprognostic (2.25e-2)" "unprognostic (4.57e-2)" "unprognostic (4.41e-2)" "unprognostic (2.90e-2)" "unprognostic (1.81e-2)" "unprognostic (4.79e-3)" "unprognostic (4.69e-1)" "unprognostic (2.78e-1)" "unprognostic (1.69e-1)" DISP1 "DISPA, DKFZP434I0428, MGC13130, MGC16796" ENSG00000154309 "Dispatched RND transporter family member 1" Q96F81 1 222815022-223005995 "Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Choroid plexus epithelial cells: 698.1;Foveolar cells: 272.1;Mesothelial cells: 329.9;Microglia: 606.3;Oligodendrocyte progenitor cells: 269.2;Sertoli cells: 713.4" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 781.3;choroid plexus epithelial cell: 544.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Mesothelial cells, Breast - Fibroblasts, Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA051411, HPA078564" Uncertain Approved "Plasma membrane" NA No "Cluster 14: Non-specific - Unknown function" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 5: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 2 "Plasma membrane" "HPA051411: , HPA078564: " "unprognostic (6.68e-2)" "unprognostic (1.07e-1)" "unprognostic (3.49e-1)" "unprognostic (2.06e-2)" "unprognostic (1.75e-1)" "unprognostic (4.02e-2)" "unprognostic (6.42e-2)" "unprognostic (8.83e-3)" "unprognostic (1.12e-1)" "validated prognostic favorable (8.23e-8)" "validated prognostic favorable (2.50e-4)" "unprognostic (2.93e-1)" "unprognostic (1.61e-1)" "unprognostic (4.13e-3)" "unprognostic (1.16e-1)" "unprognostic (5.43e-2)" "unprognostic (4.73e-2)" "unprognostic (6.55e-2)" "unprognostic (3.18e-1)" "unprognostic (1.78e-1)" "unprognostic (1.89e-1)" "unprognostic (6.66e-2)" "unprognostic (3.45e-1)" "unprognostic (2.50e-1)" "unprognostic (1.15e-1)" "unprognostic (6.75e-2)" "unprognostic (1.16e-1)" "unprognostic (1.57e-1)" "unprognostic (1.58e-2)" "unprognostic (1.89e-1)" DISP2 "C15orf36, DISPB, HsT16908, KIAA1742, LINC00594" ENSG00000140323 "Dispatched RND transporter family member 2" A7MBM2 15 40358219-40378621 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "brain: 25.8" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 21.3;Brain excitatory neurons: 45.7;Brain inhibitory neurons: 30.8;Colonocytes: 26.8;Enteric stem cells: 13.5;Enteric transient amplifying cells: 13.8;Enterocytes: 19.8;Goblet cells: 35.6;Neuroendocrine cells: 20.9;Other brain neurons: 34.3;Paneth cells: 38.7;Retinal amacrine cells: 22.9" "Cell type enhanced" "Detected in many" "upper rhombic lip: 96.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal medulla cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059903 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 2: Cerebellar granular cells - Neuronal signaling" "Nucleoplasm, Vesicles" "HPA059903: " "unprognostic (2.45e-1)" "unprognostic (2.05e-2)" "unprognostic (6.70e-2)" "potential prognostic favorable (7.15e-4)" "potential prognostic unfavorable (1.63e-4)" "unprognostic (4.66e-1)" "unprognostic (1.81e-1)" DISP3 "KIAA1337, PTCHD2" ENSG00000204624 "Dispatched RND transporter family member 3" Q9P2K9 1 11479155-11537551 "Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol metabolism, Differentiation, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "brain: 8.7;pituitary gland: 3.5;retina: 4.2;testis: 6.2" "Cell type enhanced" "Detected in some" "Astrocytes: 35.6;Brain inhibitory neurons: 19.8;Cone photoreceptor cells: 18.6;Early spermatids: 69.8;Late spermatids: 91.2;Retinal amacrine cells: 76.8;Retinal ganglion cells: 54.1;Retinal horizontal cells: 92.2;Rod photoreceptor cells: 29.7;Tuft cells: 23.1" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 59.8;hippocampal dentate gyrus: 59.6" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 7.1;Testicular Germ Cell Tumor (TCGA): 4.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Pancreas - Beta cells, Pituitary gland - Corticotropes, Prostate - Prostate glandular cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054579 Uncertain Uncertain Nucleoplasm,Cytosol NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" Nucleoplasm Cytosol "HPA054579: " "unprognostic (1.25e-3)" "unprognostic (1.18e-1)" "unprognostic (1.36e-2)" "unprognostic (6.81e-2)" "unprognostic (6.26e-2)" "unprognostic (1.87e-1)" DIXDC1 "Dixin, KIAA1735" ENSG00000150764 "DIX domain containing 1" Q155Q3 11 111927144-112022653 "Predicted intracellular proteins" "Wnt signaling pathway" "Actin-binding, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 223.2;Cone photoreceptor cells: 252.6;Ependymal cells: 245.0;Proximal tubule cells: 235.5;Respiratory ciliated cells: 295.9;Rod photoreceptor cells: 253.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 11 "eosinophil: 5.2" "Lineage enriched" "Detected in single" 11 "granulocytes: 5.2" "Low cancer specificity" "Detected in many" "Spleen - Fibroblasts_2, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039424, HPA039658, HPA061366" Approved Supported Cytosol NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 74: Non-specific - Signal transduction" "Cluster 55: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" 4 Cytosol "HPA039424: , HPA039658: , HPA061366: " "unprognostic (2.33e-2)" "unprognostic (8.34e-2)" "unprognostic (1.35e-1)" "potential prognostic unfavorable (1.05e-4)" "unprognostic (1.12e-1)" "unprognostic (7.41e-2)" "unprognostic (2.41e-1)" "unprognostic (1.83e-2)" "unprognostic (2.27e-1)" "unprognostic (6.31e-2)" "potential prognostic favorable (1.93e-6)" "unprognostic (5.38e-2)" "potential prognostic favorable (2.96e-5)" "unprognostic (1.23e-1)" "unprognostic (3.81e-2)" "unprognostic (9.63e-2)" "unprognostic (9.48e-2)" "unprognostic (3.93e-2)" "unprognostic (1.81e-1)" "unprognostic (5.75e-2)" "unprognostic (1.15e-1)" "unprognostic (4.47e-2)" "unprognostic (2.14e-2)" "unprognostic (1.29e-1)" "unprognostic (8.18e-2)" "unprognostic (7.62e-3)" "unprognostic (3.75e-2)" "unprognostic (1.09e-2)" "unprognostic (1.75e-1)" "unprognostic (1.97e-2)" "unprognostic (7.07e-2)" DKC1 "Cbf5, DKC, dyskerin, NAP57, NOLA4, XAP101" ENSG00000130826 "Dyskerin pseudouridine synthase 1" O60832 X 154762742-154777689 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Isomerase, Ribonucleoprotein, RNA-binding" "Cataract, Deafness, Disease variant, Dyskeratosis congenita" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 204.0;Esophageal basal cells: 147.9;Megakaryocyte progenitors: 145.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000166, HPA000447, HPA001022, CAB033086" Supported Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA 4000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 36: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 129 "Nucleoli fibrillar center" Nucleoplasm "CAB033086: , HPA000166: , HPA000447: , HPA001022: " "unprognostic (4.14e-2)" "unprognostic (1.71e-2)" "unprognostic (9.20e-2)" "unprognostic (2.15e-1)" "unprognostic (1.99e-1)" "unprognostic (2.49e-1)" "unprognostic (2.76e-1)" "unprognostic (5.80e-2)" "unprognostic (1.27e-3)" "potential prognostic unfavorable (9.07e-4)" "potential prognostic favorable (4.00e-4)" "unprognostic (2.84e-3)" "potential prognostic unfavorable (1.24e-4)" "validated prognostic unfavorable (1.99e-6)" "validated prognostic unfavorable (1.15e-6)" "unprognostic (4.74e-3)" "potential prognostic unfavorable (1.66e-4)" "unprognostic (4.53e-3)" "unprognostic (3.27e-3)" "unprognostic (7.35e-2)" "unprognostic (1.16e-2)" "unprognostic (2.73e-3)" "unprognostic (1.29e-1)" "potential prognostic unfavorable (8.96e-4)" "potential prognostic favorable (6.10e-4)" "unprognostic (2.09e-2)" "unprognostic (7.48e-2)" "unprognostic (2.82e-1)" "unprognostic (5.09e-1)" "unprognostic (4.20e-2)" "unprognostic (4.42e-2)" DKK1 "DKK-1, SK" ENSG00000107984 "Dickkopf WNT signaling pathway inhibitor 1" O94907 10 52314281-52318042 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 20.7;cervix: 31.9;placenta: 46.0" "Cell type enriched" "Detected in some" 14 "Decidual stromal cells: 3375.2" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 8.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skin - Macrophages, Spleen - B-cells (Spleen)" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Secreted in other tissues" "Developmental protein" NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 10 "unprognostic (3.49e-3)" "unprognostic (5.16e-2)" "unprognostic (2.75e-1)" "unprognostic (2.87e-2)" "unprognostic (7.97e-2)" "unprognostic (5.57e-3)" "unprognostic (9.45e-2)" "unprognostic (2.19e-3)" "potential prognostic unfavorable (3.17e-8)" "unprognostic (3.52e-1)" "potential prognostic favorable (1.16e-5)" "unprognostic (4.12e-3)" "unprognostic (9.24e-2)" "unprognostic (3.34e-3)" "validated prognostic unfavorable (2.07e-10)" "validated prognostic unfavorable (3.46e-4)" "unprognostic (2.23e-1)" "unprognostic (9.39e-2)" "validated prognostic unfavorable (8.95e-5)" "validated prognostic unfavorable (3.13e-5)" "unprognostic (3.46e-1)" "unprognostic (1.35e-2)" "unprognostic (1.60e-1)" "unprognostic (2.78e-2)" "unprognostic (4.37e-3)" "unprognostic (3.62e-1)" "unprognostic (4.00e-1)" DKK2 ENSG00000155011 "Dickkopf WNT signaling pathway inhibitor 2" Q9UBU2 4 106921802-107283806 "Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 14.2" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 26.1;Conjunctival goblet cells: 24.3;Fibro-adipogenic progenitors: 32.9;Fibroblasts: 27.2;Hofbauer cells: 91.1;Medullary thymic epithelial cells: 69.6;Myosatellite cells: 27.4;Other brain neurons: 21.4;Thymic myoid cells: 65.3;Thyrotrophs: 31.6;Vascular endothelial cells: 24.2" "Cell type enhanced" "Detected in many" "endothelial cell: 100.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Bone cancer: 35.1;Neuroblastoma: 19.4;Rhabdoid: 47.7" "Minor Salivary Gland - Fibroblasts" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "cerebral cortex: 2.1;midbrain: 6.6;pons: 8.2;thalamus: 7.6" "CAB009727, HPA052611" Uncertain Supported "Golgi apparatus" "Secreted in other tissues" "Developmental protein" NA NA "Cluster 13: Lung - Secretion" "Cluster 38: Sub-cortical - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 33 "Golgi apparatus" "CAB009727: , HPA052611: " "unprognostic (4.10e-2)" "unprognostic (1.75e-3)" "unprognostic (3.93e-1)" "unprognostic (1.67e-2)" "unprognostic (1.12e-1)" "unprognostic (9.31e-2)" "unprognostic (3.38e-2)" "unprognostic (1.78e-1)" "unprognostic (2.00e-2)" "unprognostic (2.31e-1)" "unprognostic (4.28e-3)" "unprognostic (5.00e-2)" "unprognostic (3.00e-1)" "unprognostic (9.73e-2)" "unprognostic (1.82e-1)" "unprognostic (2.55e-1)" "unprognostic (6.17e-2)" "unprognostic (7.53e-2)" "unprognostic (3.48e-2)" "unprognostic (2.05e-1)" DKK3 "CRRL, REIC, RIG" ENSG00000050165 "Dickkopf WNT signaling pathway inhibitor 3" Q9UBP4 11 11956207-12009769 "Plasma proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 371.6;heart muscle: 1240.0" "Cell type enriched" "Detected in many" 4 "Müller glia: 1893.7" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 135.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 7.1;memory CD8 T-cell: 4.4" "Lineage enriched" "Detected in single" 72 "T-cells: 7.1" "Cancer enhanced" "Detected in many" "Brain cancer: 311.7" "Breast - Breast myoepithelial cells, Colon - Enteric glia cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblasts_1, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Testis - Sertoli cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011868, CAB024949" Approved Supported "Nuclear bodies,Vesicles,Cytosol" "Secreted in other tissues" "Developmental protein" No No 20000000 "Cluster 35: Non-specific - Mixed function" "Cluster 33: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 11: Muller glia cells - Retinal homeostasis" 6 Vesicles "Nuclear bodies, Cytosol" "CAB024949: , HPA011868: " "unprognostic (3.57e-1)" "unprognostic (1.12e-1)" "unprognostic (6.77e-2)" "unprognostic (1.06e-1)" "unprognostic (2.51e-1)" "unprognostic (2.04e-1)" "unprognostic (1.84e-3)" "unprognostic (2.42e-2)" "unprognostic (6.48e-3)" "unprognostic (1.81e-1)" "validated prognostic favorable (7.36e-5)" "validated prognostic favorable (3.37e-4)" "unprognostic (1.12e-1)" "unprognostic (5.22e-2)" "unprognostic (3.32e-2)" "unprognostic (5.73e-2)" "unprognostic (1.46e-1)" "unprognostic (1.75e-1)" "unprognostic (2.99e-1)" "unprognostic (1.50e-2)" "unprognostic (2.00e-2)" "unprognostic (5.24e-2)" "unprognostic (2.27e-2)" "unprognostic (1.37e-1)" "unprognostic (3.87e-1)" "potential prognostic favorable (2.61e-4)" "unprognostic (7.37e-2)" "unprognostic (7.32e-3)" "unprognostic (3.96e-1)" "unprognostic (1.43e-2)" "unprognostic (2.36e-1)" DKK4 ENSG00000104371 "Dickkopf WNT signaling pathway inhibitor 4" Q9UBT3 8 42374063-42377229 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 4.6;intestine: 2.3" "Group enriched" "Detected in some" 7 "Esophageal apical cells: 36.7;Ocular epithelial cells: 20.0" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 8 "Uterine Corpus Endometrial Carcinoma (TCGA): 160.3" "Region enhanced" "Detected in many" "cerebellum: 8.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 28 "breast cancer: 169.4" "Minor Salivary Gland - Minor salivary gland basal cells, Pituitary gland - Thyrotropes, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA052916 Uncertain "Secreted in other tissues" "Developmental protein" NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 35: Non-specific - DNA binding" "Cluster 70: DU4475 - Unknown function" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 6 "HPA052916: " "unprognostic (1.24e-1)" "unprognostic (2.75e-2)" "unprognostic (1.68e-2)" "unprognostic (1.54e-1)" "unprognostic (4.56e-1)" "unprognostic (1.79e-2)" "unprognostic (4.38e-2)" "unprognostic (2.19e-1)" "unprognostic (4.20e-2)" "unprognostic (5.42e-2)" "unprognostic (1.65e-2)" "unprognostic (2.76e-3)" "unprognostic (6.56e-3)" "unprognostic (2.46e-1)" "unprognostic (8.66e-2)" "unprognostic (1.22e-2)" "unprognostic (3.42e-3)" "unprognostic (1.67e-3)" DKKL1 "CT34, SGY-1" ENSG00000104901 "Dickkopf like acrosomal protein 1" Q9UK85 19 49361783-49375116 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 299 "testis: 352.3" "Group enriched" "Detected in some" 116 "Early spermatids: 2507.9;Late primary spermatocytes: 1665.2;Late spermatids: 3112.0" "Cell type enhanced" "Detected in some" "ependymal cell: 3.0" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 8.4" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 6 "memory B-cell: 1.7" "Lineage enriched" "Detected in single" 17 "B-cells: 1.7" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB025410, HPA047194" Enhanced Approved "Vesicles,Acrosome,Equatorial segment,Mid piece" "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 5: Rhabdoid - Unknown function" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 42 "Vesicles, Acrosome, Equatorial segment" "Mid piece" "CAB025410: , HPA047194: " "unprognostic (1.11e-1)" "unprognostic (4.16e-1)" "unprognostic (3.64e-3)" "unprognostic (1.09e-1)" "unprognostic (2.50e-1)" "unprognostic (3.18e-2)" "unprognostic (2.79e-1)" "unprognostic (6.23e-2)" "unprognostic (1.32e-1)" "unprognostic (1.12e-2)" DLAT "DLTA, E2, PDC-E2" ENSG00000150768 "Dihydrolipoamide S-acetyltransferase" P10515 11 112025408-112064404 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism, Tricarboxylic acid cycle" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 83.5" "Cell type enhanced" "Detected in many" "Adipocytes: 172.1;Cardiomyocytes: 206.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003782, HPA040786, HPA062766" Supported Supported "Mitochondria,Connecting piece" NA NA 16000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 21: Non-specific - Metabolism" "Cluster 24: Non-specific - Unknown function" "Cluster 89: Adipocytes - Lipid metabolism" 32 Mitochondria "Connecting piece" "CAB003782: , HPA040786: , HPA062766: " "unprognostic (4.60e-2)" "unprognostic (5.85e-3)" "unprognostic (1.58e-1)" "unprognostic (1.11e-1)" "unprognostic (6.21e-3)" "unprognostic (2.20e-2)" "unprognostic (3.95e-2)" "unprognostic (1.07e-1)" "unprognostic (6.98e-2)" "unprognostic (5.79e-3)" "potential prognostic favorable (2.14e-10)" "unprognostic (2.61e-2)" "unprognostic (3.00e-3)" "potential prognostic unfavorable (3.42e-5)" "unprognostic (1.34e-2)" "unprognostic (3.39e-3)" "unprognostic (2.28e-2)" "unprognostic (2.99e-1)" "unprognostic (2.78e-1)" "unprognostic (2.00e-1)" "unprognostic (7.63e-3)" "unprognostic (6.44e-3)" "unprognostic (3.65e-1)" "unprognostic (8.76e-2)" "unprognostic (5.65e-3)" "unprognostic (1.63e-1)" "unprognostic (3.05e-2)" "unprognostic (1.58e-1)" "unprognostic (1.44e-1)" "unprognostic (1.20e-1)" "unprognostic (6.94e-2)" DLC1 "ARHGAP7, DLC-1, HP, p122-RhoGAP, STARD12" ENSG00000164741 "DLC1 Rho GTPase activating protein" Q96QB1 8 13083361-13604610 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 1635.4;Adrenal medulla cells: 872.2;Bergmann glia: 762.0;Cardiomyocytes: 609.6;Fibro-adipogenic progenitors: 1550.1;Leydig cells: 992.7;Oligodendrocytes: 935.0;Pericytes: 2360.9;Pituicytes/FSCs: 1344.7;Schwann cells: 956.9;Vascular smooth muscle cells: 892.6" "Group enriched" "Detected in all" 4 "pericyte: 9442.6;vascular associated smooth muscle cell: 3776.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "basophil: 4.3;non-classical monocyte: 1.1" "Group enriched" "Detected in many" 19 "granulocytes: 4.3;monocytes: 1.1" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells, Minor Salivary Gland - Endothelial cells, Prostate - Endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017753, HPA061655, CAB080186" Uncertain Supported "Endoplasmic reticulum,Vesicles,Cytosol" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 11: White matter - Signal transduction" "Cluster 72: Neuronal - Signal transduction" "Cluster 110: Mural cells - ECM organization" 5 Cytosol "Endoplasmic reticulum, Vesicles" "CAB080186: , HPA017753: , HPA061655: " "unprognostic (1.13e-2)" "unprognostic (1.59e-1)" "unprognostic (1.14e-1)" "unprognostic (2.78e-1)" "unprognostic (4.39e-2)" "unprognostic (1.71e-3)" "unprognostic (6.17e-2)" "potential prognostic unfavorable (1.26e-5)" "unprognostic (1.49e-1)" "unprognostic (2.82e-1)" "potential prognostic favorable (9.34e-5)" "unprognostic (4.63e-3)" "unprognostic (2.34e-1)" "unprognostic (2.64e-2)" "unprognostic (3.03e-2)" "unprognostic (4.30e-3)" "unprognostic (9.01e-2)" "unprognostic (3.85e-3)" "unprognostic (2.62e-1)" "unprognostic (2.23e-2)" "unprognostic (6.58e-3)" "unprognostic (7.78e-3)" "unprognostic (6.05e-2)" "unprognostic (9.45e-2)" "unprognostic (2.90e-1)" "unprognostic (2.38e-2)" "unprognostic (7.23e-2)" "unprognostic (1.03e-3)" "unprognostic (1.40e-2)" "unprognostic (1.90e-1)" "unprognostic (6.20e-2)" DLD "DLDH, E3, GCSL, LAD, OGDC-E3" ENSG00000091140 "Dihydrolipoamide dehydrogenase" P09622 7 107891162-107931730 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 215.8;tongue: 228.7" "Cell type enhanced" "Detected in all" "Epicardial cells: 263.8;Parietal cells: 399.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044849 Supported Approved "Nucleoplasm,Cytokinetic bridge,Primary cilium,Mitochondria,Principal piece" Yes NA 8900000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 52: Non-specific - Cellular respiration" "Cluster 45: Non-specific - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 48 Mitochondria "Nucleoplasm, Cytokinetic bridge, Primary cilium, Principal piece" "HPA044849: " "unprognostic (3.44e-1)" "unprognostic (4.05e-3)" "unprognostic (1.33e-2)" "unprognostic (2.74e-1)" "unprognostic (1.45e-2)" "unprognostic (2.63e-2)" "unprognostic (6.68e-2)" "unprognostic (1.97e-2)" "unprognostic (1.44e-1)" "unprognostic (7.87e-3)" "potential prognostic favorable (1.06e-8)" "unprognostic (8.15e-2)" "unprognostic (7.64e-3)" "unprognostic (2.17e-1)" "unprognostic (1.19e-3)" "unprognostic (9.74e-3)" "unprognostic (3.59e-1)" "unprognostic (2.35e-1)" "unprognostic (1.15e-1)" "unprognostic (3.00e-3)" "unprognostic (7.93e-2)" "unprognostic (2.34e-1)" "unprognostic (1.20e-1)" "unprognostic (2.27e-1)" "unprognostic (1.42e-1)" "unprognostic (1.74e-2)" "unprognostic (2.61e-1)" "unprognostic (3.29e-1)" "unprognostic (1.73e-1)" "unprognostic (1.06e-2)" "unprognostic (5.63e-2)" DLEC1 "CFAP81, DLC1, FAP81" ENSG00000008226 "DLEC1 cilia and flagella associated protein" Q9Y238 3 38039205-38124025 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 14.4;fallopian tube: 17.9;pituitary gland: 9.2;testis: 12.4" "Group enriched" "Detected in many" 4 "Choroid plexus epithelial cells: 96.8;Endometrial ciliated cells: 106.7;Ependymal cells: 238.7;Epididymal efferent duct ciliated cells: 67.2;Fallopian tube ciliated cells: 137.6;Respiratory ciliated cells: 210.4" "Group enriched" "Detected in many" 11 "choroid plexus epithelial cell: 76.9;ependymal cell: 243.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA019077 Enhanced Supported Cytosol NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 65: Non-specific - Unknown function" "Cluster 34: Ciliated cells - Cilia assembly & function" Cytosol "HPA019077: " "unprognostic (1.88e-2)" "unprognostic (2.06e-1)" "unprognostic (1.29e-1)" "unprognostic (5.53e-2)" "unprognostic (7.63e-3)" "unprognostic (3.11e-1)" "unprognostic (4.95e-2)" "unprognostic (4.19e-3)" "unprognostic (2.71e-1)" "unprognostic (1.28e-1)" "unprognostic (3.78e-2)" DLEU7 FLJ44882 ENSG00000186047 "Deleted in lymphocytic leukemia 7" Q6UYE1 13 50519364-50843939 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 9 "brain: 5.2" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 41.0;Brain inhibitory neurons: 57.1;Early spermatids: 45.6;Kupffer cells: 98.4;Macrophages: 37.4;Microglia: 276.8;Oligodendrocyte progenitor cells: 46.5;Other brain neurons: 37.6;Thymocytes: 39.0" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 340.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adrenal gland - Macrophages, Lung - Macrophages, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA053750 Uncertain NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" "HPA053750: " "unprognostic (3.46e-1)" "unprognostic (1.10e-1)" "unprognostic (9.02e-2)" DLG1 "dJ1061C18.1.1, DLGH1, hdlg, SAP-97, SAP97" ENSG00000075711 "Discs large MAGUK scaffold protein 1" Q12959 3 197042560-197299330 "Predicted intracellular proteins, Transporters" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 2027.4" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 2251.0;oligodendrocyte: 2396.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016307, HPA069593" Supported Approved "Vesicles,Plasma membrane,Basal body" NA NA 9500 "Cluster 24: Non-specific - Transcription" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 72: Neuronal - Signal transduction" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 75 Vesicles "Plasma membrane, Basal body" "CAB016307: , HPA069593: " "unprognostic (6.62e-2)" "unprognostic (2.29e-2)" "unprognostic (2.42e-2)" "unprognostic (4.40e-3)" "unprognostic (3.00e-1)" "unprognostic (4.57e-3)" "unprognostic (8.65e-2)" "unprognostic (3.52e-1)" "unprognostic (1.69e-1)" "unprognostic (1.21e-3)" "potential prognostic favorable (4.02e-5)" "unprognostic (2.43e-1)" "unprognostic (1.48e-1)" "unprognostic (7.17e-2)" "unprognostic (6.79e-2)" "unprognostic (1.13e-1)" "unprognostic (8.54e-3)" "unprognostic (1.46e-1)" "unprognostic (7.96e-2)" "unprognostic (3.08e-2)" "unprognostic (7.32e-3)" "unprognostic (2.94e-3)" "unprognostic (3.42e-3)" "unprognostic (6.12e-2)" "unprognostic (4.72e-2)" "unprognostic (1.18e-2)" "unprognostic (3.90e-2)" "unprognostic (3.01e-1)" "unprognostic (3.81e-1)" "unprognostic (4.44e-2)" "unprognostic (3.14e-1)" DLG2 "chapsyn-110, PPP1R58, PSD-93, PSD93" ENSG00000150672 "Discs large MAGUK scaffold protein 2" Q15700 11 83455012-85628335 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 46.7" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 3711.7;Brain inhibitory neurons: 3586.7;Cone photoreceptor cells: 6564.3;Oligodendrocyte progenitor cells: 2976.1;Oligodendrocytes: 4673.4;Other brain neurons: 2372.4;Pituicytes/FSCs: 4337.8;Podocytes: 2874.7;Retinal bipolar cells: 12775.9" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 10.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 7 "Bone cancer: 45.9" "Liver - Hepatocytes, Lung - Fibroblasts_2, Skin - Keratinocyte (other), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021307, HPA023896, CAB072341" Enhanced Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 34: Non-specific - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 18 "Plasma membrane" Vesicles "CAB072341: , HPA021307: , HPA023896: " "unprognostic (1.08e-3)" "unprognostic (1.07e-1)" "unprognostic (2.14e-1)" "unprognostic (1.31e-1)" "unprognostic (1.66e-2)" "unprognostic (5.06e-2)" "unprognostic (5.61e-3)" "potential prognostic favorable (1.57e-4)" "unprognostic (3.24e-1)" "unprognostic (4.06e-2)" "unprognostic (3.90e-2)" "unprognostic (1.78e-3)" "unprognostic (5.56e-2)" "unprognostic (3.38e-2)" "unprognostic (2.37e-1)" "unprognostic (1.34e-1)" "unprognostic (5.86e-2)" "unprognostic (3.78e-3)" "unprognostic (1.81e-2)" "unprognostic (9.30e-2)" DLG3 "KIAA1232, MRX90, NE-Dlg, NEDLG, PPP1R82, SAP-102, SAP102" ENSG00000082458 "Discs large MAGUK scaffold protein 3" Q92796 X 70444835-70505490 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 88.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatic stellate cells, Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001733, HPA078130" Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 60: Stomach - Digestion" "Cluster 51: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 22 "Nucleoplasm, Nucleoli" "HPA001733: , HPA078130: " "unprognostic (2.19e-3)" "potential prognostic unfavorable (4.84e-5)" "unprognostic (7.86e-2)" "unprognostic (9.57e-2)" "unprognostic (1.26e-1)" "unprognostic (3.97e-2)" "unprognostic (9.12e-2)" "unprognostic (2.25e-3)" "unprognostic (2.13e-2)" "unprognostic (2.49e-1)" "potential prognostic favorable (4.60e-6)" "unprognostic (3.70e-3)" "unprognostic (3.67e-2)" "unprognostic (3.97e-1)" "unprognostic (5.10e-3)" "unprognostic (1.83e-1)" "unprognostic (2.32e-1)" "unprognostic (5.65e-3)" "unprognostic (4.16e-2)" "unprognostic (3.49e-1)" "unprognostic (7.77e-2)" "unprognostic (5.05e-2)" "unprognostic (4.33e-2)" "unprognostic (2.62e-1)" "unprognostic (1.72e-1)" "unprognostic (2.55e-2)" "unprognostic (6.34e-2)" "unprognostic (1.83e-2)" "unprognostic (2.08e-1)" "unprognostic (4.82e-2)" "unprognostic (2.52e-1)" DLG4 "PSD-95, PSD95, SAP-90, SAP90" ENSG00000132535 "Discs large MAGUK scaffold protein 4" P78352 17 7187187-7219841 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "brain: 211.2;retina: 200.9" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 48.6;Cone photoreceptor cells: 209.1;Retinal bipolar cells: 64.8;Rod photoreceptor cells: 141.9" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 28.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Pituitary gland - Lactotropes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001999, CAB002000, HPA010122, HPA071006" Enhanced Uncertain "Nucleoplasm,Plasma membrane,Primary cilium,Primary cilium tip,Centrosome,Basal body,Cytosol" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" 78 "Nucleoplasm, Centrosome, Basal body" "Plasma membrane, Primary cilium, Primary cilium tip, Cytosol" "CAB001999: , CAB002000: , HPA010122: , HPA071006: " "unprognostic (1.24e-1)" "unprognostic (5.94e-2)" "unprognostic (2.91e-1)" "unprognostic (4.86e-2)" "unprognostic (7.69e-2)" "unprognostic (1.07e-1)" "unprognostic (2.09e-2)" "unprognostic (8.02e-2)" "unprognostic (1.32e-1)" "unprognostic (2.80e-2)" "unprognostic (2.31e-2)" "unprognostic (9.33e-2)" "unprognostic (7.07e-2)" "unprognostic (3.59e-3)" "unprognostic (5.72e-3)" "unprognostic (3.67e-2)" "unprognostic (6.83e-3)" "unprognostic (2.66e-1)" "unprognostic (1.76e-1)" "unprognostic (2.05e-2)" "unprognostic (3.85e-1)" "potential prognostic favorable (3.85e-4)" "unprognostic (7.64e-3)" "unprognostic (1.24e-1)" "unprognostic (9.42e-2)" "unprognostic (7.68e-2)" "unprognostic (4.41e-1)" "unprognostic (1.71e-1)" "unprognostic (1.21e-1)" "unprognostic (9.84e-2)" "unprognostic (3.21e-1)" DLG5 "KIAA0583, P-dlg" ENSG00000151208 "Discs large MAGUK scaffold protein 5" Q8TDM6 10 77790791-77926755 "Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 49.7;Bergmann glia: 63.1;Choroid plexus epithelial cells: 129.9;Distal convoluted tubule cells: 95.4;Ependymal cells: 59.1;Loop of henle epithelial cells: 59.3;Papillary tip epithelial cells: 110.0;Podocytes: 243.4;Proximal tubule cells: 55.0;Renal collecting duct intercalated cells: 107.9;Renal collecting duct principal cells: 56.6;Renal connecting tubule cells: 66.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001746 Supported "Cell Junctions" NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 102: Non-specific - Mixed function" 18 "Cell Junctions" "HPA001746: " "unprognostic (2.49e-2)" "unprognostic (9.68e-2)" "unprognostic (2.40e-1)" "unprognostic (5.97e-3)" "unprognostic (5.18e-1)" "unprognostic (2.14e-1)" "unprognostic (8.98e-2)" "potential prognostic favorable (5.06e-6)" "unprognostic (5.20e-2)" "unprognostic (5.98e-3)" "potential prognostic unfavorable (2.33e-9)" "unprognostic (5.03e-2)" "unprognostic (2.16e-2)" "potential prognostic unfavorable (1.91e-5)" "unprognostic (1.30e-2)" "unprognostic (2.91e-3)" "unprognostic (9.47e-3)" "unprognostic (4.11e-2)" "unprognostic (2.07e-1)" "unprognostic (2.28e-2)" "unprognostic (1.59e-1)" "unprognostic (8.58e-2)" "potential prognostic unfavorable (5.49e-5)" "unprognostic (2.30e-2)" "potential prognostic unfavorable (7.40e-4)" "unprognostic (3.62e-3)" "unprognostic (3.95e-1)" "unprognostic (1.01e-1)" "unprognostic (3.24e-1)" "unprognostic (1.28e-1)" "unprognostic (1.48e-1)" DLGAP1 "DAP-1, GKAP, SAPAP1" ENSG00000170579 "DLG associated protein 1" O14490 18 3496032-4455307 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 51.7" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 2524.2;Brain inhibitory neurons: 3102.6;Endometrial glandular cells: 1041.1;Endometrial luminal cells: 903.4;Epicardial cells: 950.6;Oligodendrocyte progenitor cells: 1644.7;Pituicytes/FSCs: 3341.3;Prostatic glandular cells: 1134.4;Retinal amacrine cells: 2892.8;Retinal ganglion cells: 1483.3;Sertoli cells: 2068.6" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 9.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells, Prostate - Prostate glandular cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078234 Approved Vesicles,Cytosol NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" 12 Cytosol Vesicles "HPA078234: " "unprognostic (2.59e-3)" "unprognostic (1.24e-1)" "unprognostic (1.62e-2)" "potential prognostic favorable (4.91e-7)" "unprognostic (7.15e-2)" "unprognostic (6.47e-2)" "unprognostic (8.50e-2)" "unprognostic (6.26e-3)" "unprognostic (4.25e-1)" "unprognostic (6.19e-2)" "unprognostic (3.29e-1)" "unprognostic (1.11e-2)" "unprognostic (5.72e-2)" DLGAP2 "C8orf68, DAP-2, ERICH1-AS1" ENSG00000198010 "DLG associated protein 2" Q9P1A6 8 737628-1708476 "Nuclear receptors, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.1;testis: 11.5" "Group enriched" "Detected in many" 5 "Bergmann glia: 277.3;Brain excitatory neurons: 864.3;Brain inhibitory neurons: 871.2;Other brain neurons: 389.5" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Neuroblastoma: 1.5" "Adipose visceral - Mesothelial cells, Kidney - Proximal tubular cells, Pituitary gland - Somatotropes, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA030320 Uncertain NA NA "Cluster 67: Testis - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 35: Neurons - Synaptic function & neurogenesis" 7 "HPA030320: " "unprognostic (1.97e-1)" DLGAP3 "DAP3, SAPAP3" ENSG00000116544 "DLG associated protein 3" O95886 1 34865436-34929650 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 43.8" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 55.0;Brain inhibitory neurons: 69.3;Cone photoreceptor cells: 31.1;Early spermatids: 28.1;Gonadotrophs: 19.1;Hofbauer cells: 21.6;Late primary spermatocytes: 22.2;Late spermatids: 30.8;Other brain neurons: 32.3;Retinal amacrine cells: 38.9;Retinal ganglion cells: 30.9;Retinal horizontal cells: 28.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 9.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 5.3" "Adipose visceral - Macrophages, Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026445, HPA027304" Enhanced Approved "Endoplasmic reticulum,Plasma membrane,Midbody" Yes NA "Cluster 13: Non-specific - Mitochondria" "Cluster 78: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" 8 "Endoplasmic reticulum, Plasma membrane" Midbody "HPA026445: , HPA027304: " "unprognostic (2.99e-2)" "unprognostic (1.29e-1)" "potential prognostic favorable (5.51e-4)" "unprognostic (2.46e-1)" "unprognostic (7.82e-3)" "unprognostic (2.34e-1)" "unprognostic (1.42e-2)" DLGAP4 "DAP4, KIAA0964, SAPAP4" ENSG00000080845 "DLG associated protein 4" Q9Y2H0 20 36306336-36528637 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 302.5;Oocytes: 285.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054105, HPA056378" Approved Approved "Nucleoplasm,Vesicles,Focal adhesion sites" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 109: Neurons - Neuronal signaling" 9 Nucleoplasm "Vesicles, Focal adhesion sites" "HPA054105: , HPA056378: " "unprognostic (3.53e-2)" "unprognostic (7.92e-2)" "unprognostic (2.96e-1)" "unprognostic (1.24e-1)" "unprognostic (3.44e-1)" "unprognostic (1.92e-1)" "unprognostic (1.28e-1)" "unprognostic (6.15e-2)" "unprognostic (1.09e-1)" "unprognostic (2.89e-3)" "unprognostic (1.72e-1)" "unprognostic (1.93e-1)" "unprognostic (4.70e-2)" "potential prognostic unfavorable (7.42e-7)" "unprognostic (2.09e-1)" "unprognostic (5.72e-2)" "unprognostic (5.69e-2)" "unprognostic (3.55e-2)" "unprognostic (2.55e-1)" "unprognostic (2.66e-2)" "unprognostic (2.72e-1)" "unprognostic (2.29e-2)" "potential prognostic unfavorable (5.68e-4)" "unprognostic (2.95e-2)" "unprognostic (1.57e-1)" "unprognostic (6.27e-2)" "unprognostic (3.28e-2)" "unprognostic (1.62e-1)" "unprognostic (1.27e-1)" "unprognostic (1.85e-1)" "unprognostic (2.99e-1)" DLGAP5 "DLG1, DLG7, HURP, KIAA0008" ENSG00000126787 "DLG associated protein 5" Q15398 14 55148112-55191608 "Plasma proteins, Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 28.0;lymphoid tissue: 39.1;testis: 16.3" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 39.3;Early primary spermatocytes: 58.4;Erythrocyte progenitors: 233.0;Late primary spermatocytes: 71.9;Megakaryocyte progenitors: 81.2;Monocyte progenitors: 161.5;Neutrophil progenitors: 63.2;Oocytes: 280.9" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 5.4" "Lineage enriched" "Detected in many" 5 "T-cells: 5.4" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA005546, HPA071028" Enhanced Supported "Mitotic spindle,Cytosol" Yes Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 11: White matter - Signal transduction" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 27: Non-specific - Cell proliferation" 22 Cytosol "Mitotic spindle" "HPA005546: , HPA071028: " "unprognostic (2.67e-3)" "unprognostic (1.32e-1)" "unprognostic (4.87e-2)" "unprognostic (5.48e-2)" "unprognostic (1.75e-3)" "unprognostic (1.39e-1)" "unprognostic (1.24e-1)" "unprognostic (7.09e-2)" "unprognostic (2.26e-2)" "potential prognostic unfavorable (9.43e-5)" "validated prognostic unfavorable (5.92e-6)" "validated prognostic unfavorable (5.02e-4)" "validated prognostic unfavorable (5.64e-6)" "validated prognostic unfavorable (9.30e-9)" "potential prognostic unfavorable (2.27e-5)" "unprognostic (7.56e-3)" "unprognostic (2.99e-2)" "unprognostic (8.77e-2)" "unprognostic (2.32e-1)" "unprognostic (2.78e-2)" "validated prognostic unfavorable (1.28e-5)" "validated prognostic unfavorable (6.12e-4)" "unprognostic (1.39e-1)" "unprognostic (1.62e-2)" "unprognostic (1.81e-1)" "unprognostic (5.90e-2)" "unprognostic (7.61e-2)" "unprognostic (1.72e-1)" "unprognostic (2.04e-1)" DLK1 "Delta1, FA1, pG2, Pref-1, ZOG" ENSG00000185559 "Delta like non-canonical Notch ligand 1" P80370 14 100725705-100738224 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adrenal gland: 1265.2;pituitary gland: 731.7;placenta: 1533.9" "Group enriched" "Detected in many" 5 "Adrenal cortex cells: 966.3;Adrenal medulla cells: 1616.8;Fibroblasts: 448.6;Leydig cells: 1014.0;Pericytes: 608.8;Somatotrophs: 817.9" "Group enriched" "Detected in some" 5 "eccentric medium spiny neuron: 8.3;medium spiny neuron: 6.1;splatter: 14.4" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 105.8;Testicular Germ Cell Tumor (TCGA): 125.9" "Region enhanced" "Detected in many" "hypothalamus: 353.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Neuroblastoma: 489.9;Rhabdoid: 329.1" "Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Somatotropes" "Region enhanced" "Detected in many" "hypothalamus: 111.6" "Group enriched" "Detected in many" 5 "hypothalamus: 53.8;midbrain: 203.8" "CAB005872, HPA062262" Enhanced Approved "Golgi apparatus" NA NA 1500000 "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 65: Non-specific - Unknown function" "Cluster 108: Fibroblasts - ECM organization" 12 "Golgi apparatus" "CAB005872: , HPA062262: " "unprognostic (4.27e-2)" "unprognostic (3.80e-2)" "unprognostic (2.20e-1)" "unprognostic (6.68e-1)" "unprognostic (1.58e-1)" "unprognostic (2.10e-1)" "unprognostic (1.82e-1)" "unprognostic (7.16e-3)" "unprognostic (1.36e-1)" "unprognostic (2.78e-1)" "unprognostic (2.72e-1)" "unprognostic (3.21e-1)" "unprognostic (1.02e-1)" "unprognostic (1.75e-1)" "unprognostic (8.56e-2)" "unprognostic (6.27e-2)" "unprognostic (2.97e-2)" "unprognostic (4.71e-1)" "unprognostic (8.03e-2)" "unprognostic (8.30e-2)" DLK2 "EGFL9, MGC2487" ENSG00000171462 "Delta like non-canonical Notch ligand 2" Q6UY11 6 43450352-43456632 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 11.7;prostate: 12.4;skin 1: 12.3" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 17.0;Basal prostatic cells: 50.8;Breast myoepithelial cells: 80.1;Epididymal basal cells: 70.1;Esophageal basal cells: 34.8;Respiratory basal cells: 42.0;Retinal horizontal cells: 22.0;Salivary basal cells: 33.9;Salivary myoepithelial cells: 29.7" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 18.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 38.6" "Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA061223, HPA068672, HPA070955" Uncertain Approved Nucleoplasm,Nucleoli,Vesicles No No 23000 "Cluster 2: Non-specific - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 26: Keratinocytes - Keratinization" Nucleoplasm "Nucleoli, Vesicles" "HPA061223: , HPA068672: , HPA070955: " "unprognostic (1.55e-1)" "unprognostic (7.33e-3)" "unprognostic (1.92e-1)" "unprognostic (3.26e-1)" "unprognostic (2.53e-1)" "unprognostic (2.93e-1)" "unprognostic (2.73e-3)" "unprognostic (1.61e-1)" "potential prognostic unfavorable (1.12e-5)" "unprognostic (6.24e-2)" "unprognostic (1.32e-3)" "unprognostic (9.95e-2)" "unprognostic (5.86e-2)" "potential prognostic favorable (1.20e-4)" "unprognostic (7.44e-2)" "unprognostic (1.71e-2)" "unprognostic (1.50e-1)" "unprognostic (7.41e-2)" "unprognostic (1.49e-3)" "unprognostic (1.41e-3)" "unprognostic (5.69e-2)" "unprognostic (2.72e-2)" DLL1 ENSG00000198719 "Delta like canonical Notch ligand 1" O00548 6 170282206-170306565 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Notch signaling pathway" "Developmental protein" "Autism spectrum disorder, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 42.7" "Cell type enhanced" "Detected in some" "Astrocytes: 22.6;Bergmann glia: 23.8;Brain inhibitory neurons: 12.1;Choroid plexus epithelial cells: 13.7;Ependymal cells: 60.6;Loop of henle epithelial cells: 9.9;Oligodendrocyte progenitor cells: 36.7;Oligodendrocytes: 25.5;Other brain neurons: 13.2;Podocytes: 12.1;Renal collecting duct intercalated cells: 47.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "NK-cell: 3.3" "Lineage enriched" "Detected in single" 8 "NK-cells: 3.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 13.3" "Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA001255 Approved "Plasma membrane" NA NA 410000 "Cluster 15: NK-cells - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 11: White matter - Signal transduction" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" 3 "Plasma membrane" "HPA001255: " "unprognostic (5.04e-2)" "unprognostic (1.18e-1)" "unprognostic (2.72e-1)" "unprognostic (8.41e-3)" "unprognostic (1.34e-1)" "unprognostic (2.19e-2)" "unprognostic (2.22e-2)" "potential prognostic favorable (8.67e-6)" "unprognostic (7.90e-2)" "unprognostic (1.41e-1)" "validated prognostic favorable (3.60e-7)" "validated prognostic favorable (4.98e-4)" "unprognostic (2.64e-3)" "potential prognostic favorable (2.34e-6)" "unprognostic (2.50e-1)" "unprognostic (6.69e-2)" "unprognostic (4.20e-1)" "unprognostic (3.02e-2)" "unprognostic (2.14e-1)" "potential prognostic favorable (5.99e-4)" "unprognostic (3.78e-1)" "unprognostic (2.31e-1)" "unprognostic (2.26e-1)" "unprognostic (2.24e-1)" "unprognostic (5.94e-2)" "unprognostic (2.44e-2)" "unprognostic (4.52e-2)" DLL3 SCDO1 ENSG00000090932 "Delta like canonical Notch ligand 3" Q9NYJ7 19 39498895-39508481 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Notch signaling pathway" "Developmental protein" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "brain: 27.1" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 46.4;Early primary spermatocytes: 17.3;Epididymal basal cells: 13.0;Oligodendrocyte progenitor cells: 49.3;Oocytes: 96.7;Other brain neurons: 12.2;Undifferentiated spermatogonia: 27.3" "Cell type enhanced" "Detected in many" "oligodendrocyte precursor cell: 67.7" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 60.2;Skin Cutaneous Melanoma (TCGA): 26.8" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "memory B-cell: 2.6;naive CD8 T-cell: 1.4" "Group enriched" "Detected in many" 13 "B-cells: 2.6;T-cells: 1.4" "Cancer enhanced" "Detected in many" "Neuroblastoma: 17.9;skin cancer: 27.5" "Testis - Spermatogonia" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA024559, HPA056533" Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" Nucleoplasm "Golgi apparatus, Plasma membrane" "HPA024559: , HPA056533: " "unprognostic (8.13e-2)" "unprognostic (1.43e-1)" "unprognostic (4.14e-2)" "unprognostic (7.22e-2)" "potential prognostic favorable (6.19e-4)" "unprognostic (2.92e-2)" "unprognostic (1.49e-1)" "unprognostic (4.00e-2)" "unprognostic (4.37e-2)" "unprognostic (1.73e-1)" "unprognostic (3.53e-1)" "potential prognostic unfavorable (4.99e-5)" DLL4 ENSG00000128917 "Delta like canonical Notch ligand 4" Q9NR61 15 40929340-40939073 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Angiogenesis, Differentiation, Neurogenesis, Notch signaling pathway, Sensory transduction, Vision" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 17.2;Colonocytes: 55.5;Goblet cells: 95.4;Lymphatic endothelial cells: 55.5;Neuroendocrine cells: 39.1;Tuft cells: 69.2;Vascular endothelial cells: 68.9" "Group enriched" "Detected in many" 21 "endothelial cell: 81.0;vascular associated smooth muscle cell: 25.7" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 41.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 4.8;lung cancer: 4.7" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Liver - Vascular endothelial cells, Prostate - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA023392 Uncertain NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 1 "HPA023392: " "unprognostic (9.38e-2)" "unprognostic (1.33e-3)" "unprognostic (2.31e-1)" "potential prognostic unfavorable (4.02e-4)" "unprognostic (3.13e-2)" "unprognostic (1.18e-1)" "unprognostic (4.26e-1)" "unprognostic (2.37e-1)" "unprognostic (9.72e-2)" "unprognostic (1.30e-1)" "validated prognostic favorable (7.71e-4)" "validated prognostic favorable (5.11e-4)" "unprognostic (1.21e-3)" "unprognostic (3.69e-2)" "unprognostic (2.20e-1)" "unprognostic (4.18e-1)" "potential prognostic unfavorable (6.99e-4)" "unprognostic (1.71e-3)" "unprognostic (1.34e-1)" "unprognostic (3.74e-1)" "unprognostic (1.71e-1)" "unprognostic (3.98e-2)" "unprognostic (9.79e-2)" "unprognostic (4.15e-2)" "unprognostic (2.22e-1)" "unprognostic (1.75e-1)" "unprognostic (2.10e-1)" "unprognostic (1.38e-1)" "unprognostic (3.47e-1)" "unprognostic (5.77e-3)" "unprognostic (1.52e-2)" DLST "DLTS, KGD2, OGDC-E2" ENSG00000119689 "Dihydrolipoamide S-succinyltransferase" P36957 14 74881891-74903743 "Citric acid cycle related proteins, Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Minor Salivary Gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003010 Supported Supported Nucleoplasm,Mitochondria,Cytosol NA NA 110000 "Cluster 41: Basophils - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 85 Nucleoplasm "Mitochondria, Cytosol" "HPA003010: " "unprognostic (3.98e-1)" "unprognostic (6.41e-2)" "unprognostic (5.13e-3)" "unprognostic (5.53e-2)" "unprognostic (7.69e-2)" "unprognostic (1.47e-1)" "unprognostic (1.30e-1)" "unprognostic (1.46e-1)" "unprognostic (6.20e-2)" "unprognostic (1.50e-1)" "potential prognostic favorable (5.55e-8)" "unprognostic (1.04e-3)" "potential prognostic favorable (6.36e-5)" "unprognostic (8.16e-2)" "unprognostic (5.12e-2)" "unprognostic (1.63e-2)" "unprognostic (7.81e-2)" "unprognostic (1.24e-1)" "unprognostic (6.36e-3)" "unprognostic (5.02e-2)" "unprognostic (9.11e-2)" "unprognostic (4.62e-2)" "unprognostic (7.24e-3)" "unprognostic (3.31e-2)" "unprognostic (2.49e-2)" "unprognostic (5.35e-2)" "unprognostic (6.00e-2)" "unprognostic (1.08e-1)" "unprognostic (2.54e-1)" "unprognostic (2.35e-1)" "unprognostic (3.88e-1)" DLX1 ENSG00000144355 "Distal-less homeobox 1" P56177 2 172084740-172089677 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "brain: 16.9" "Group enriched" "Detected in some" 10 "Adrenal medulla cells: 10.6;Brain inhibitory neurons: 17.6;Conjunctival goblet cells: 5.8;Megakaryocytes: 6.2;Other brain neurons: 19.4;Schwann cells: 13.9;Tuft cells: 11.5" "Cell type enhanced" "Detected in some" "CGE interneuron: 84.9;LAMP5-LHX6 and Chandelier: 28.3;MGE interneuron: 42.4" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 6.9;Prostate Adenocarcinoma (TCGA): 7.4" "Region enhanced" "Detected in many" "hypothalamus: 43.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal medulla cells, Skin - Hair cortex cells, Skin - Inner root sheath cells" "Group enriched" "Detected in many" 5 "basal ganglia: 28.6;olfactory bulb: 82.6" "Region enriched" "Detected in many" 4 "olfactory bulb: 67.3" "HPA007175, HPA045884" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 109: Neurons - Neuronal signaling" Nucleoplasm "Vesicles, Cytosol" "HPA007175: , HPA045884: " "unprognostic (1.01e-1)" "unprognostic (3.23e-1)" "unprognostic (5.79e-2)" "unprognostic (3.38e-3)" "unprognostic (1.22e-1)" "unprognostic (2.58e-2)" "unprognostic (1.52e-1)" "unprognostic (4.00e-2)" DLX2 TES-1 ENSG00000115844 "Distal-less homeobox 2" Q07687 2 172099438-172102900 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 2.9" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 10.6;Brain inhibitory neurons: 4.7;Breast hormone-responsive cells: 3.3;Breast secretory cells: 3.0;Conjunctival goblet cells: 2.9;Early spermatids: 7.1;Innate lymphoid cells: 4.2;Melanocytes: 4.1;Other brain neurons: 5.6;Schwann cells: 9.5;Tuft cells: 11.5" "Cell type enhanced" "Detected in some" "CGE interneuron: 16.3;eccentric medium spiny neuron: 7.6;LAMP5-LHX6 and Chandelier: 10.3;MGE interneuron: 10.6" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "hypothalamus: 8.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal medulla cells, Skin - Hair cortex cells, Skin - Inner root sheath cells" "Region enhanced" "Detected in many" "olfactory bulb: 29.4" "Region enriched" "Detected in many" 5 "olfactory bulb: 36.3" HPA056965 Approved "Nuclear speckles" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 20: Non-specific - Transcription regulation" 2 "Nuclear speckles" "HPA056965: " "unprognostic (7.18e-2)" "unprognostic (1.62e-1)" "unprognostic (3.82e-1)" "unprognostic (9.29e-2)" "unprognostic (1.09e-1)" "unprognostic (2.87e-1)" "unprognostic (3.79e-1)" DLX3 ENSG00000064195 "Distal-less homeobox 3" O60479 17 49990005-49995224 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Amelogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "skin 1: 51.9" "Group enriched" "Detected in some" 4 "Cytotrophoblasts: 45.0;Extravillous trophoblasts: 97.2;Migrating cytotrophoblasts: 53.5;Syncytiotrophoblasts: 111.3" "Cell type enriched" "Detected in single" 8 "ependymal cell: 3.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 15.5" "Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary gland basal cells, Skin - Inner root sheath cells, Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" HPA031164 Approved Nucleoplasm,Cytosol NA NA "Cluster 37: Skin - Keratinization" "Cluster 46: Brainstem - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 7 Nucleoplasm Cytosol "HPA031164: " "unprognostic (7.04e-2)" "unprognostic (2.44e-1)" "unprognostic (2.94e-1)" "unprognostic (3.32e-2)" "unprognostic (1.38e-2)" "potential prognostic favorable (4.48e-5)" "unprognostic (2.94e-2)" "unprognostic (7.10e-2)" "unprognostic (1.31e-1)" "unprognostic (1.63e-2)" "unprognostic (1.01e-1)" "unprognostic (5.11e-2)" "unprognostic (1.39e-1)" "unprognostic (6.66e-3)" "unprognostic (2.05e-1)" "unprognostic (6.77e-3)" "unprognostic (1.48e-1)" "unprognostic (1.45e-1)" "unprognostic (2.78e-1)" "unprognostic (2.33e-1)" DLX4 "BP1, DLX7, DLX8, DLX9" ENSG00000108813 "Distal-less homeobox 4" Q92988 17 49968588-49974959 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 3.3;skin 1: 2.9" "Group enriched" "Detected in some" 4 "Extravillous trophoblasts: 102.2;Migrating cytotrophoblasts: 29.8" "Cell type enhanced" "Detected in single" "ependymal cell: 1.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 9.0" "Skin - Hair cortex cells, Skin - Inner root sheath cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA059933 Uncertain Supported Nucleoplasm NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 46: Brainstem - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 2 Nucleoplasm "HPA059933: " "unprognostic (8.19e-2)" "unprognostic (6.04e-2)" "unprognostic (2.37e-1)" "unprognostic (3.11e-2)" "unprognostic (1.71e-1)" "unprognostic (1.09e-1)" "unprognostic (1.98e-1)" "unprognostic (3.12e-2)" "potential prognostic favorable (1.49e-4)" "unprognostic (1.30e-1)" "unprognostic (2.25e-1)" "unprognostic (3.48e-1)" "unprognostic (1.25e-2)" "unprognostic (2.65e-1)" "unprognostic (1.12e-1)" DLX5 ENSG00000105880 "Distal-less homeobox 5" P56178 7 97020396-97024950 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Osteogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 13.2;placenta: 11.0;skin 1: 26.1" "Group enriched" "Detected in some" 4 "Cytotrophoblasts: 199.2;Endometrial ciliated cells: 163.2;Endometrial glandular cells: 132.7;Endometrial luminal cells: 274.1;Extravillous trophoblasts: 319.9;Migrating cytotrophoblasts: 196.0;Syncytiotrophoblasts: 361.2" "Cell type enhanced" "Detected in some" "CGE interneuron: 28.2;LAMP5-LHX6 and Chandelier: 22.8;MGE interneuron: 13.1" "Cancer enriched" "Detected in many" 6 "Uterine Corpus Endometrial Carcinoma (TCGA): 163.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells" "Group enriched" "Detected in many" 4 "basal ganglia: 13.5;olfactory bulb: 29.8" "Group enriched" "Detected in many" 4 "basal ganglia: 9.9;olfactory bulb: 24.1" HPA005670 Approved Approved Nucleoplasm NA NA "Cluster 37: Skin - Keratinization" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 1 Nucleoplasm "HPA005670: " "unprognostic (2.87e-1)" "unprognostic (2.11e-1)" "unprognostic (1.99e-1)" "unprognostic (1.33e-2)" "unprognostic (1.26e-1)" "unprognostic (2.85e-1)" "unprognostic (4.52e-2)" "unprognostic (1.29e-2)" "potential prognostic favorable (2.42e-6)" "unprognostic (5.21e-2)" "unprognostic (2.59e-3)" "unprognostic (2.38e-2)" "unprognostic (2.09e-2)" "unprognostic (1.60e-1)" "unprognostic (3.47e-2)" "unprognostic (2.94e-2)" "unprognostic (3.12e-1)" "unprognostic (1.99e-1)" "unprognostic (2.64e-3)" "unprognostic (1.86e-1)" "unprognostic (4.80e-2)" "unprognostic (1.40e-2)" DLX6 ENSG00000006377 "Distal-less homeobox 6" P56179 7 97005553-97011040 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.2;testis: 5.2" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 38.2;Endometrial ciliated cells: 33.8;Endometrial glandular cells: 21.9;Endometrial luminal cells: 37.7;Extravillous trophoblasts: 97.2;Late primary spermatocytes: 30.4;Migrating cytotrophoblasts: 44.9;Oocytes: 64.5;Syncytiotrophoblasts: 18.1;Undifferentiated spermatogonia: 14.5" "Group enriched" "Detected in some" 14 "CGE interneuron: 17.6;eccentric medium spiny neuron: 14.5;LAMP5-LHX6 and Chandelier: 19.2;medium spiny neuron: 16.5;MGE interneuron: 12.1;splatter: 5.4" "Cancer enriched" "Detected in many" 5 "Uterine Corpus Endometrial Carcinoma (TCGA): 30.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 17.8" "Colon - Enteric glia cells, Skin - Keratinocyte (granular), Testis - Late spermatids" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "basal ganglia: 31.1;olfactory bulb: 35.6" "HPA030608, HPA061460" Uncertain Approved "Nuclear bodies" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" "Nuclear bodies" "HPA030608: , HPA061460: " "unprognostic (4.06e-2)" "unprognostic (2.48e-1)" "unprognostic (6.38e-2)" "unprognostic (2.18e-1)" "unprognostic (1.14e-2)" "unprognostic (1.99e-1)" "unprognostic (1.41e-2)" "unprognostic (8.33e-3)" "unprognostic (9.95e-2)" "unprognostic (5.61e-2)" "unprognostic (3.20e-3)" "unprognostic (5.09e-1)" "unprognostic (1.03e-1)" "unprognostic (2.02e-2)" DMAC1 "C9orf123, MGC4730, TMEM261" ENSG00000137038 "Distal membrane arm assembly component 1" Q96GE9 9 7796500-7888380 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 380.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014585 Approved NA NA "Cluster 24: Non-specific - Transcription" "Cluster 52: Non-specific - Cellular respiration" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 97: Non-specific - Cellular respiration" "HPA014585: " "unprognostic (1.90e-1)" "unprognostic (1.79e-1)" "unprognostic (5.55e-2)" "unprognostic (5.27e-2)" "unprognostic (7.75e-2)" "unprognostic (1.89e-1)" "unprognostic (1.96e-1)" "unprognostic (6.54e-3)" "unprognostic (3.25e-2)" "validated prognostic favorable (5.84e-7)" "validated prognostic favorable (9.33e-4)" "potential prognostic favorable (8.14e-7)" "unprognostic (1.76e-1)" "unprognostic (4.13e-2)" "unprognostic (2.37e-1)" "unprognostic (2.35e-1)" "unprognostic (4.40e-2)" "unprognostic (3.85e-2)" "unprognostic (3.23e-1)" "potential prognostic favorable (7.30e-4)" "unprognostic (2.62e-1)" "unprognostic (5.80e-2)" "unprognostic (9.29e-3)" "unprognostic (1.55e-1)" "unprognostic (8.49e-3)" "unprognostic (2.21e-1)" "unprognostic (1.02e-1)" "unprognostic (5.31e-2)" "potential prognostic favorable (3.66e-4)" DMAC2 "ATP5SL, FLJ10241" ENSG00000105341 "Distal membrane arm assembly component 2" Q9NW81 19 41431318-41440717 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 94.8;Esophageal basal cells: 77.5;Extravillous trophoblasts: 80.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041427 Approved Approved Mitochondria NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 45: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 27: Non-specific - Cell proliferation" 1 Mitochondria "HPA041427: " "unprognostic (1.45e-3)" "unprognostic (4.22e-2)" "unprognostic (2.36e-1)" "unprognostic (1.30e-2)" "unprognostic (1.38e-1)" "unprognostic (1.16e-2)" "unprognostic (2.95e-1)" "unprognostic (3.86e-1)" "unprognostic (1.28e-1)" "validated prognostic favorable (8.64e-8)" "validated prognostic favorable (2.24e-4)" "unprognostic (5.24e-3)" "potential prognostic unfavorable (3.02e-4)" "unprognostic (1.84e-3)" "unprognostic (3.10e-2)" "unprognostic (1.17e-1)" "unprognostic (2.20e-1)" "unprognostic (1.28e-2)" "unprognostic (4.54e-2)" "unprognostic (1.40e-1)" "unprognostic (3.48e-1)" "unprognostic (2.19e-1)" "unprognostic (5.85e-2)" "unprognostic (7.98e-2)" "unprognostic (7.48e-2)" "unprognostic (2.55e-1)" "unprognostic (1.98e-1)" "unprognostic (1.73e-1)" "unprognostic (2.00e-1)" DMAC2L "ATP5S, ATPW, HSU79253" ENSG00000125375 "Distal membrane arm assembly component 2 like" Q99766 14 50312324-50335558 "Predicted intracellular proteins" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 312.4;Late primary spermatocytes: 242.4;Late spermatids: 191.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062690 Approved Nucleoplasm,Mitochondria NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 40: Non-specific - Mixed function" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" "Nucleoplasm, Mitochondria" "HPA062690: " "unprognostic (2.49e-2)" "unprognostic (3.54e-1)" "unprognostic (5.44e-2)" "unprognostic (1.25e-1)" "unprognostic (2.62e-2)" "unprognostic (7.38e-3)" "unprognostic (1.49e-2)" "unprognostic (1.47e-1)" "unprognostic (2.02e-1)" "potential prognostic favorable (6.27e-8)" "unprognostic (2.00e-3)" "unprognostic (3.00e-2)" "unprognostic (1.30e-1)" "unprognostic (2.09e-1)" "unprognostic (1.02e-1)" "unprognostic (8.41e-2)" "unprognostic (1.03e-1)" "unprognostic (4.02e-1)" "unprognostic (1.12e-1)" "unprognostic (1.31e-1)" "unprognostic (1.33e-1)" "unprognostic (2.11e-2)" "unprognostic (5.21e-2)" "unprognostic (6.10e-2)" "unprognostic (4.51e-3)" "unprognostic (2.99e-2)" "unprognostic (2.32e-1)" "unprognostic (2.96e-1)" "unprognostic (1.13e-1)" DMAP1 "DNMAP1, DNMTAP1, EAF2, FLJ11543, KIAA1425, MEAF2, SWC4" ENSG00000178028 "DNA methyltransferase 1 associated protein 1" Q9NPF5 1 44213455-44220681 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Growth regulation, Transcription, Transcription regulation" "Activator, Chromatin regulator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 88.6;Late spermatids: 101.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028419, CAB033018, HPA069527" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 37: Non-specific - mRNA processing" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 110 Nucleoplasm Cytosol "CAB033018: , HPA028419: , HPA069527: " "unprognostic (1.44e-1)" "unprognostic (4.29e-3)" "unprognostic (1.21e-1)" "unprognostic (8.00e-3)" "potential prognostic favorable (9.75e-4)" "unprognostic (2.37e-1)" "unprognostic (2.66e-1)" "unprognostic (9.59e-3)" "unprognostic (6.03e-2)" "unprognostic (3.43e-1)" "potential prognostic favorable (1.91e-6)" "unprognostic (3.25e-2)" "unprognostic (1.19e-2)" "potential prognostic unfavorable (3.40e-5)" "unprognostic (3.99e-3)" "unprognostic (4.16e-2)" "unprognostic (2.34e-1)" "unprognostic (3.05e-1)" "unprognostic (3.02e-1)" "unprognostic (2.53e-1)" "unprognostic (3.45e-2)" "unprognostic (3.25e-3)" "unprognostic (2.68e-2)" "unprognostic (9.35e-2)" "unprognostic (5.42e-2)" "unprognostic (2.41e-1)" "unprognostic (2.12e-2)" "unprognostic (6.83e-2)" "unprognostic (1.93e-1)" "unprognostic (1.19e-1)" "unprognostic (8.80e-2)" DMBT1 "Gp-340, GP340, hensin, muclin, SALSA, vomeroglandin" ENSG00000187908 "Deleted in malignant brain tumors 1" Q9UGM3 10 122560665-122643736 "Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Antiviral defense, Differentiation, Host-virus interaction, Protein transport, Transport" "Developmental protein" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 19 "intestine: 1551.2;salivary gland: 487.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 357.6;Enteric stem cells: 135.1;Enteric transient amplifying cells: 307.8;Enterocytes: 142.7;Gastric progenitor cells: 717.7;Lacrimal acinar cells: 1081.6;Paneth cells: 228.2;Salivary acinar cells: 664.7;Salivary myoepithelial cells: 156.0;Submucosal glandular cells: 644.8" "Cell type enriched" "Detected in single" 8 "oligodendrocyte: 5.4" "Group enriched" "Detected in many" 5 "Colon Adenocarcinoma (TCGA): 194.1;Lung Adenocarcinoma (TCGA): 109.7;Pancreatic Adenocarcinoma (TCGA): 132.2;Rectum Adenocarcinoma (TCGA): 107.3;Stomach Adenocarcinoma (TCGA): 321.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "pancreatic cancer: 26.1" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Urothelial cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA040778 Enhanced Approved "Centriolar satellite" "Secreted in other tissues" Transport NA NA 17000000 "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 30: White matter - Myelination" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 4 "Centriolar satellite" "HPA040778: " "unprognostic (1.22e-1)" "unprognostic (5.09e-2)" "unprognostic (6.38e-2)" "unprognostic (1.44e-2)" "unprognostic (5.47e-2)" "unprognostic (4.77e-2)" "unprognostic (2.91e-2)" "unprognostic (1.70e-1)" "unprognostic (3.69e-2)" "unprognostic (2.73e-2)" "unprognostic (1.58e-1)" "unprognostic (8.97e-2)" "unprognostic (2.69e-1)" "unprognostic (5.37e-2)" "unprognostic (2.82e-2)" "unprognostic (2.61e-1)" "unprognostic (2.77e-2)" "unprognostic (2.03e-1)" "unprognostic (4.40e-3)" "unprognostic (1.23e-2)" "unprognostic (2.60e-1)" "unprognostic (3.51e-2)" "unprognostic (2.42e-1)" DMBX1 "Atx, MBX, OTX3, PAXB" ENSG00000197587 "Diencephalon/mesencephalon homeobox 1" Q8NFW5 1 46489836-46516216 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Brain inhibitory neurons: 15.2;Corticotrophs: 2.2;Differentiating spermatogonia: 4.6;Early primary spermatocytes: 3.0;Epicardial cells: 2.3;Gastric progenitor cells: 2.6;Oocytes: 4.6;Retinal bipolar cells: 8.1;Retinal ganglion cells: 3.9;Undifferentiated spermatogonia: 3.7;Urothelial cells: 2.0" "Cell type enriched" "Detected in some" 39 "midbrain-derived inhibitory: 126.8" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "thalamus: 16.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Pituitary gland - Corticotropes, Skin - Sebaceous gland cells, Stomach - Mitotic cells (Stomach)" "Group enriched" "Detected in some" 7 "midbrain: 1.5;pons and medulla: 1.0" "Region enhanced" "Detected in some" "thalamus: 5.6" NA NA "Cluster 19: Astrocytes - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "unprognostic (2.25e-3)" "unprognostic (1.02e-2)" "unprognostic (3.18e-1)" "unprognostic (1.99e-1)" "unprognostic (2.32e-1)" "unprognostic (2.54e-1)" "unprognostic (4.29e-3)" DMC1 LIM15 ENSG00000100206 "DNA meiotic recombinase 1" Q14565 22 38518948-38570204 "Predicted intracellular proteins" "Cell cycle, Meiosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 11.0" "Cell type enriched" "Detected in many" 10 "Early primary spermatocytes: 269.5" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 6.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Prostate - Fibroblasts, Spleen - Mitotic cells (Spleen), Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA001232, CAB015397" Enhanced Approved Nucleoplasm NA NA "Cluster 39: Testis - Nuclear processes" "Cluster 37: Neurons - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 3: Early primary spermatocytes - Early meiosis" 15 Nucleoplasm "CAB015397: , HPA001232: " "unprognostic (7.39e-2)" "unprognostic (5.85e-2)" "unprognostic (2.92e-1)" "unprognostic (1.44e-1)" "unprognostic (9.67e-2)" "unprognostic (1.50e-1)" "unprognostic (8.09e-2)" "unprognostic (2.61e-2)" "unprognostic (1.16e-1)" "unprognostic (2.85e-1)" "unprognostic (1.04e-1)" "unprognostic (7.16e-2)" "unprognostic (3.43e-2)" "unprognostic (1.09e-1)" "unprognostic (1.70e-1)" "unprognostic (4.17e-2)" "unprognostic (1.42e-2)" DMD "BMD, DXS142, DXS164, DXS206, DXS230, DXS239, DXS268, DXS269, DXS270, DXS272, MRX85" ENSG00000198947 Dystrophin P11532 X 31097677-33339609 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transporters" Actin-binding "Cancer-related genes, Cardiomyopathy, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 1918.6;Cardiomyocytes: 6295.2;Cone photoreceptor cells: 2591.8;Myonuclei: 14979.2;Rod photoreceptor cells: 3789.5;Salivary myoepithelial cells: 2593.1;Thymic myoid cells: 7067.3" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Testicular Germ Cell Tumor (TCGA): 55.9;Thyroid Carcinoma (TCGA): 21.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast myoepithelial cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000119, HPA002725, HPA023885" Enhanced NA NA 120000 "Cluster 32: Basophils - Transcription" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 51: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 30 "CAB000119: , HPA002725: , HPA023885: " "unprognostic (1.05e-1)" "unprognostic (2.18e-2)" "unprognostic (1.39e-1)" "unprognostic (2.01e-1)" "unprognostic (1.04e-1)" "unprognostic (9.21e-2)" "unprognostic (5.06e-2)" "unprognostic (4.59e-2)" "unprognostic (6.60e-2)" "unprognostic (5.17e-2)" "potential prognostic favorable (1.01e-5)" "unprognostic (1.22e-3)" "unprognostic (5.02e-3)" "unprognostic (6.05e-2)" "unprognostic (2.92e-3)" "potential prognostic favorable (3.00e-4)" "unprognostic (1.62e-1)" "unprognostic (2.07e-1)" "unprognostic (4.82e-2)" "unprognostic (9.56e-2)" "unprognostic (4.15e-2)" "unprognostic (3.61e-2)" "unprognostic (2.01e-1)" "unprognostic (2.54e-1)" "unprognostic (5.69e-3)" "unprognostic (2.56e-1)" "unprognostic (1.20e-2)" "unprognostic (4.53e-3)" "unprognostic (1.70e-1)" "unprognostic (1.78e-1)" "unprognostic (2.09e-1)" DMGDH ME2GLYDH ENSG00000132837 "Dimethylglycine dehydrogenase" Q9UI17 5 78997564-79236038 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 18 "kidney: 158.2;liver: 265.4" "Cell type enhanced" "Detected in many" "Adipocytes: 185.6;Distal convoluted tubule cells: 150.5;Gonadotrophs: 132.9;Hepatocytes: 251.3;Loop of henle epithelial cells: 156.3;Proximal tubule cells: 229.9" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" 7 "Kidney Renal Clear Cell Carcinoma (TCGA): 39.0;Kidney Renal Papillary Cell Carcinoma (TCGA): 17.0;Liver Hepatocellular Carcinoma (TCGA): 32.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Adrenocortical cancer: 8.5;Kidney cancer: 9.2;liver cancer: 3.8" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA036441, HPA036442, HPA077849" Enhanced Supported Mitochondria NA NA 1300000 "Cluster 16: Liver & Kidney - Metabolism" "Cluster 46: Brainstem - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 89: Adipocytes - Lipid metabolism" Mitochondria "HPA036441: , HPA036442: , HPA077849: " "unprognostic (3.83e-2)" "unprognostic (1.45e-1)" "unprognostic (4.64e-1)" "unprognostic (1.95e-1)" "validated prognostic favorable (1.10e-10)" "validated prognostic favorable (8.83e-4)" "unprognostic (8.15e-3)" "validated prognostic favorable (1.71e-4)" "validated prognostic favorable (1.57e-4)" "unprognostic (1.04e-1)" "unprognostic (1.89e-1)" "unprognostic (4.06e-2)" "unprognostic (8.42e-2)" DMKN ZD52F10 ENSG00000161249 Dermokine Q6E0U4 19 35497220-35513658 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "skin 1: 4625.2" "Group enriched" "Detected in many" 4 "Esophageal apical cells: 1448.4;Suprabasal keratinocytes: 5448.0" "Cell type enhanced" "Detected in many" "ependymal cell: 39.8" "Cancer enhanced" "Detected in all" "Head and Neck Squamous Cell Carcinoma (TCGA): 458.5;Skin Cutaneous Melanoma (TCGA): 453.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 11.7" "Group enriched" "Detected in many" 5 "NK-cells: 11.7;T-cells: 6.4" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Colon - Enteric glia cells, Lung - Alveolar cells type 2" "Region enhanced" "Detected in all" "basal ganglia: 51.9" "Low region specificity" "Detected in some" "HPA029406, HPA071641" Enhanced Approved Nucleoplasm,Cytosol "Secreted in other tissues" "No annotated function" NA NA 12000000 "Cluster 15: NK-cells - Unknown function" "Cluster 37: Skin - Keratinization" "Cluster 49: Hindbrain - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 26: Keratinocytes - Keratinization" 6 "Nucleoplasm, Cytosol" "HPA029406: , HPA071641: " "unprognostic (1.63e-2)" "unprognostic (1.82e-2)" "unprognostic (4.48e-2)" "unprognostic (1.16e-1)" "unprognostic (1.40e-1)" "unprognostic (6.51e-2)" "unprognostic (1.68e-2)" "unprognostic (7.89e-2)" "unprognostic (5.98e-2)" "unprognostic (1.68e-3)" "unprognostic (5.30e-3)" "unprognostic (1.87e-2)" "unprognostic (2.00e-2)" "unprognostic (4.44e-2)" "unprognostic (2.64e-2)" "unprognostic (1.01e-1)" "unprognostic (2.00e-1)" "unprognostic (2.31e-1)" "unprognostic (9.46e-2)" "unprognostic (9.21e-2)" "unprognostic (1.92e-2)" "potential prognostic unfavorable (1.48e-5)" "unprognostic (7.13e-2)" "unprognostic (5.55e-2)" "unprognostic (3.87e-3)" "unprognostic (8.78e-2)" "unprognostic (2.73e-1)" "unprognostic (3.36e-1)" "unprognostic (4.36e-2)" "unprognostic (5.50e-2)" DMP1 ENSG00000152592 "Dentin matrix acidic phosphoprotein 1" Q13316 4 87650280-87664361 "Disease related genes, Human disease related genes, Predicted secreted proteins" Biomineralization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Early spermatids: 1.3;Fibroblasts: 1.1;Late primary spermatocytes: 1.7;Pericytes: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 21 "Rhabdoid: 15.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037465 Approved "Secreted to extracellular matrix" Other NA NA 48000 "Cluster 3: Rhabdoid - Membrane components" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 1 "HPA037465: " DMPK "DM, DM1, DM1PK, DMK, MDPK, MT-PK" ENSG00000104936 "DM1 protein kinase" Q09013 19 45769709-45782552 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 145.9;skeletal muscle: 193.1;tongue: 138.8" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 72.5;Smooth muscle cells: 112.7;Thymic myoid cells: 115.6;Vascular smooth muscle cells: 114.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Liver - Vascular endothelial cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007164, HPA008905" Enhanced Uncertain Vesicles,Cytosol NA NA "Cluster 41: Striated muscle - Muscle contraction" "Cluster 19: Astrocytes - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 62: Smooth muscle cells - Muscle contraction" 7 Cytosol Vesicles "HPA007164: , HPA008905: " "unprognostic (1.60e-2)" "unprognostic (1.09e-1)" "unprognostic (3.44e-1)" "unprognostic (2.41e-1)" "unprognostic (9.48e-2)" "unprognostic (1.14e-1)" "unprognostic (4.44e-2)" "unprognostic (1.23e-1)" "unprognostic (1.29e-1)" "unprognostic (1.51e-1)" "unprognostic (2.42e-2)" "unprognostic (1.15e-1)" "unprognostic (6.12e-2)" "unprognostic (6.11e-2)" "unprognostic (1.14e-1)" "unprognostic (2.09e-1)" "unprognostic (5.97e-2)" "unprognostic (2.08e-1)" "unprognostic (1.65e-1)" "unprognostic (1.28e-1)" "unprognostic (2.88e-3)" "unprognostic (4.48e-3)" "unprognostic (2.47e-1)" "unprognostic (4.63e-2)" "unprognostic (9.29e-2)" "unprognostic (2.82e-3)" "unprognostic (7.97e-3)" "unprognostic (7.74e-2)" "unprognostic (2.15e-1)" "potential prognostic unfavorable (9.82e-4)" "unprognostic (3.15e-2)" DMRT1 "CT154, DMT1" ENSG00000137090 "Doublesex and mab-3 related transcription factor 1" Q9Y5R6 9 841690-969090 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Sexual differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 83 "testis: 25.2" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 331.1;Early primary spermatocytes: 33.3;Early spermatids: 72.0;Sertoli cells: 213.2;Undifferentiated spermatogonia: 106.7" "Group enriched" "Detected in some" 5 "choroid plexus epithelial cell: 3.1;ependymal cell: 2.1" "Cancer enriched" "Detected in some" 10 "Testicular Germ Cell Tumor (TCGA): 11.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "lymphoma: 4.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA027850 Enhanced NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 1 "HPA027850: " "unprognostic (9.45e-2)" "unprognostic (6.19e-3)" DMRT2 ENSG00000173253 "Doublesex and mab-3 related transcription factor 2" Q9Y5R5 9 1049858-1057552 "Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "kidney: 32.6;lymphoid tissue: 17.8;parathyroid gland: 39.1;skeletal muscle: 12.2" "Cell type enhanced" "Detected in some" "Epididymal clear cells: 265.4;Medullary thymic epithelial cells: 45.6;Myosatellite cells: 31.5;Renal collecting duct intercalated cells: 192.7;Respiratory ionocytes: 144.8;Salivary ionocytes: 90.5" "Cell type enriched" "Detected in some" 7 "oligodendrocyte: 16.7" "Cancer enriched" "Detected in many" 19 "Kidney Chromophobe (TCGA): 239.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Esophageal cancer: 5.8" "Kidney - Intercalated cells, Minor Salivary Gland - Minor salivary gland ductal cells" "Low region specificity" "Detected in some" "Region enhanced" "Detected in single" "cerebral cortex: 2.5" "HPA003498, HPA029297" Uncertain Approved "Nucleoplasm,Nucleoli,Vesicles,Centriolar satellite" NA NA "Cluster 33: Thyroid gland - Tissue development" "Cluster 11: White matter - Signal transduction" "Cluster 24: Non-specific - Unknown function" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 1 "Nucleoplasm, Nucleoli" "Vesicles, Centriolar satellite" "HPA003498: , HPA029297: " "unprognostic (1.02e-2)" "unprognostic (8.98e-2)" "potential prognostic favorable (7.33e-4)" "unprognostic (1.01e-1)" "unprognostic (6.53e-2)" "unprognostic (2.94e-2)" "unprognostic (1.79e-2)" "unprognostic (1.11e-1)" "unprognostic (2.86e-1)" "potential prognostic unfavorable (2.77e-4)" "unprognostic (2.37e-2)" "unprognostic (1.02e-2)" "unprognostic (1.67e-2)" "unprognostic (4.96e-2)" "unprognostic (1.25e-1)" "unprognostic (1.63e-1)" DMRT3 DMRTA3 ENSG00000064218 "Doublesex and mab-3 related transcription factor 3" Q9NQL9 9 976655-991732 "Predicted intracellular proteins, Transcription factors" "Differentiation, Sexual differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 9.3;parathyroid gland: 25.3;testis: 9.1" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 20.2;Conjunctival goblet cells: 3.9;Differentiating spermatogonia: 7.4;Early primary spermatocytes: 31.0;Early spermatids: 4.7;Ependymal cells: 9.2;Myosatellite cells: 5.7;Respiratory basal cells: 12.3;Respiratory deuterosomal cells: 10.4;Respiratory secretory cells: 14.1;Undifferentiated spermatogonia: 5.1" "Group enriched" "Detected in some" 7 "choroid plexus epithelial cell: 12.6;ependymal cell: 4.1" "Cancer enhanced" "Detected in some" "Thyroid Carcinoma (TCGA): 6.7" "Region enriched" "Detected in many" 7 "choroid plexus: 22.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "thyroid cancer: 1.3" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.3" HPA077685 Approved NA NA "Cluster 69: Parathyroid gland - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 3: Early primary spermatocytes - Early meiosis" 66 "HPA077685: " "unprognostic (7.49e-2)" "unprognostic (4.09e-2)" "unprognostic (4.14e-2)" "unprognostic (1.87e-2)" "unprognostic (9.70e-3)" "potential prognostic unfavorable (9.58e-4)" DMRTA1 ENSG00000176399 "DMRT like family A1" Q5VZB9 9 22446824-22455740 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 7.8" "Cell type enhanced" "Detected in many" "Endometrial luminal cells: 17.3;Esophageal apical cells: 23.3;Esophageal suprabasal cells: 27.8;Hepatocytes: 36.3;Lacrimal acinar cells: 17.2;Retinal pigment epithelial cells: 42.6;Salivary acinar cells: 18.0" "Cell type enhanced" "Detected in some" "Bergmann glia: 6.7;choroid plexus epithelial cell: 11.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Kidney - Proximal tubular cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA044764, HPA062253" Uncertain Approved Vesicles NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 2 Vesicles "HPA044764: , HPA062253: " "unprognostic (9.59e-2)" "unprognostic (8.31e-2)" "unprognostic (1.21e-1)" "validated prognostic favorable (7.62e-10)" "validated prognostic favorable (2.87e-5)" "unprognostic (1.07e-2)" "unprognostic (1.24e-1)" "potential prognostic favorable (3.09e-4)" "unprognostic (2.50e-1)" "unprognostic (3.33e-2)" "unprognostic (1.32e-1)" "unprognostic (1.72e-1)" "unprognostic (9.65e-2)" "unprognostic (1.29e-1)" DMRTA2 ENSG00000142700 "DMRT like family A2" Q96SC8 1 50417550-50423443 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 1.4;pituitary gland: 1.9;testis: 1.7" "Cell type enhanced" "Detected in some" "Conjunctival goblet cells: 11.7;Gonadotrophs: 5.6;Late primary spermatocytes: 15.7;Ocular epithelial cells: 46.8;Pituitary stem cells: 13.0;Respiratory basal cells: 13.5;Respiratory deuterosomal cells: 12.4;Respiratory ionocytes: 5.1;Respiratory secretory cells: 11.3;Submucosal glandular cells: 9.0" "Cell type enhanced" "Detected in some" "oligodendrocyte: 1.5" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 9.1" "Region enhanced" "Detected in many" "white matter: 5.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 5.2;Sarcoma: 5.4" "Testis - Late spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA043098, HPA062958" Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 39: Testis - Nuclear processes" "Cluster 11: White matter - Signal transduction" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 100: Stratified epithelial cells - Barrier functions" Mitochondria Nucleoplasm "HPA043098: , HPA062958: " "unprognostic (2.34e-1)" "unprognostic (6.16e-3)" "unprognostic (1.90e-2)" "potential prognostic unfavorable (3.24e-5)" "unprognostic (1.70e-2)" "unprognostic (2.77e-2)" "unprognostic (2.41e-2)" "unprognostic (8.63e-2)" "unprognostic (1.43e-1)" DMRTB1 ENSG00000143006 "DMRT like family B with proline rich C-terminal 1" Q96MA1 1 53459399-53467488 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 73 "testis: 59.1" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 221.2;Early primary spermatocytes: 196.9;Early spermatids: 44.2;Late primary spermatocytes: 210.7;Late spermatids: 207.1;Oocytes: 55.3" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Testicular Germ Cell Tumor (TCGA): 2.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 64 "Gastric cancer: 6.4" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA036490, HPA058553" Enhanced NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 21 "HPA036490: , HPA058553: " "unprognostic (3.06e-1)" DMRTC1 ENSG00000269502 "DMRT like family C1" Q5HYR2 X 72872025-72943837 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 12.0;pituitary gland: 12.1" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 1.1;Brain inhibitory neurons: 1.0;Cone photoreceptor cells: 2.1;Early primary spermatocytes: 4.6;Gonadotrophs: 2.2;Lactotrophs: 2.1;Oligodendrocyte progenitor cells: 1.1;Other brain neurons: 1.1;Rod photoreceptor cells: 1.0;Sertoli cells: 2.2;Somatotrophs: 1.7;Thyrotrophs: 1.7" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Region enhanced" "Detected in many" "hypothalamus: 16.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046874, HPA046992" Uncertain Approved "Nucleoplasm,Intermediate filaments" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 78: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 3: Early primary spermatocytes - Early meiosis" Nucleoplasm "Intermediate filaments" "HPA046874: , HPA046992: " "unprognostic (3.91e-1)" DMRTC1B ENSG00000184911 "DMRT like family C1B" Q5HYR2 X 72776890-72848803 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.8;pituitary gland: 16.0" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 10.6;Brain excitatory neurons: 2.2;Brain inhibitory neurons: 2.5;Choroid plexus epithelial cells: 2.0;Gonadotrophs: 4.3;Lactotrophs: 4.2;Other brain neurons: 2.1;Pituitary stem cells: 2.1;Retinal amacrine cells: 2.1;Somatotrophs: 3.7;Thyrotrophs: 3.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046874, HPA046992" Uncertain Approved "Nucleoplasm,Intermediate filaments" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 78: Brain - Neuronal signaling" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 61: BICR 18 - Protein kinases" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" Nucleoplasm "Intermediate filaments" "HPA046874: , HPA046992: " "unprognostic (3.58e-2)" "unprognostic (6.73e-2)" "unprognostic (8.82e-2)" "unprognostic (9.88e-3)" "unprognostic (1.99e-2)" "unprognostic (1.28e-1)" "unprognostic (1.89e-3)" "unprognostic (1.29e-1)" "unprognostic (1.91e-2)" DMRTC2 ENSG00000142025 "DMRT like family C2" Q8IXT2 19 41844743-41852333 "Predicted intracellular proteins, Transcription factors" "Differentiation, Sexual differentiation, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 108 "testis: 38.5" "Cell type enriched" "Detected in some" 8 "Early primary spermatocytes: 347.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Spermatocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA045016 Uncertain NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 4: Non-specific - Transcription" "Cluster 3: Early primary spermatocytes - Early meiosis" "HPA045016: " DMTF1 "DMP1, DMTF, hDMP1, MRUL" ENSG00000135164 "Cyclin D binding myb like transcription factor 1" Q9Y222 7 87152409-87196337 "Predicted intracellular proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "Activator, DNA-binding" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023846 Supported Supported Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 39: Testis - Nuclear processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 1 Nucleoplasm "HPA023846: " "unprognostic (1.33e-2)" "unprognostic (1.18e-1)" "unprognostic (3.83e-1)" "unprognostic (2.61e-2)" "unprognostic (2.14e-1)" "unprognostic (4.29e-2)" "unprognostic (1.49e-1)" "unprognostic (1.60e-2)" "unprognostic (1.37e-1)" "unprognostic (5.90e-3)" "unprognostic (2.76e-1)" "unprognostic (2.18e-3)" "unprognostic (6.99e-2)" "unprognostic (1.27e-3)" "unprognostic (1.58e-1)" "unprognostic (1.17e-1)" "unprognostic (5.81e-2)" "unprognostic (3.01e-2)" "unprognostic (9.42e-2)" "unprognostic (2.56e-1)" "unprognostic (1.20e-1)" "unprognostic (1.51e-1)" "unprognostic (7.24e-3)" "unprognostic (9.02e-2)" "potential prognostic favorable (5.14e-4)" "unprognostic (4.60e-2)" "unprognostic (3.96e-2)" "unprognostic (7.59e-2)" "unprognostic (1.64e-1)" "unprognostic (5.89e-2)" "unprognostic (2.21e-1)" DMTN "DMT, EPB49" ENSG00000158856 "Dematin actin binding protein" Q08495 8 22048995-22082527 "Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 319.1" "Group enriched" "Detected in many" 4 "Erythrocytes: 244.2;Megakaryocytes: 253.4;Platelets: 624.5" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 171.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "gdT-cell: 1.7;MAIT T-cell: 1.7;memory CD4 T-cell: 3.7;memory CD8 T-cell: 1.6;naive CD4 T-cell: 1.5;naive CD8 T-cell: 1.5;neutrophil: 1.1;T-reg: 3.2" "Group enriched" "Detected in many" 9 "granulocytes: 1.1;T-cells: 3.7" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Heart muscle - Cardiomyocytes, Minor Salivary Gland - Minor salivary glandular cells, Skin - Keratinocyte (other), Spleen - Erythrocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024290, HPA058487" Uncertain NA NA 3000000 "Cluster 33: Non-specific - ATP binding" "Cluster 78: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 17 "HPA024290: , HPA058487: " "potential prognostic favorable (5.75e-4)" "unprognostic (2.37e-2)" "unprognostic (7.29e-2)" "unprognostic (1.28e-3)" "unprognostic (1.37e-3)" "unprognostic (5.56e-3)" "unprognostic (6.61e-3)" "unprognostic (1.57e-1)" "unprognostic (3.73e-2)" "potential prognostic favorable (8.44e-8)" "unprognostic (3.49e-3)" "unprognostic (1.13e-2)" "unprognostic (1.25e-2)" "unprognostic (3.18e-2)" "unprognostic (1.60e-1)" "unprognostic (3.53e-1)" "unprognostic (4.88e-2)" "unprognostic (8.24e-2)" "unprognostic (4.55e-2)" "unprognostic (2.66e-2)" "unprognostic (1.77e-1)" "unprognostic (2.54e-1)" "unprognostic (6.79e-2)" "unprognostic (1.89e-1)" "unprognostic (2.49e-2)" "unprognostic (5.30e-3)" "unprognostic (1.74e-1)" "unprognostic (2.17e-1)" "unprognostic (7.22e-2)" DMWD "D19S593E, DMR-N9, gene59" ENSG00000185800 "DM1 locus, WD repeat containing" Q09019 19 45782947-45792845 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 44.8;Platelets: 15.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Prostate - Smooth muscle cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA068172, HPA069843" Approved Approved "Plasma membrane,Actin filaments" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 74: Non-specific - Signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 8 "Plasma membrane, Actin filaments" "HPA068172: , HPA069843: " "unprognostic (1.29e-1)" "unprognostic (1.08e-1)" "unprognostic (4.41e-2)" "unprognostic (5.07e-2)" "unprognostic (2.20e-1)" "unprognostic (2.50e-1)" "unprognostic (6.20e-2)" "unprognostic (1.29e-1)" "unprognostic (1.95e-1)" "unprognostic (3.29e-2)" "unprognostic (7.57e-2)" "unprognostic (4.19e-1)" "unprognostic (1.38e-1)" "potential prognostic unfavorable (9.44e-5)" "unprognostic (1.92e-1)" "unprognostic (9.04e-3)" "unprognostic (6.99e-2)" "unprognostic (1.10e-1)" "unprognostic (1.61e-2)" "unprognostic (1.47e-2)" "unprognostic (3.64e-1)" "unprognostic (2.12e-1)" "unprognostic (6.78e-2)" "unprognostic (2.92e-1)" "unprognostic (2.75e-1)" "unprognostic (5.26e-3)" "unprognostic (2.51e-1)" "unprognostic (1.84e-1)" "unprognostic (1.16e-1)" "unprognostic (9.46e-3)" "unprognostic (1.12e-1)" DMXL1 ENSG00000172869 "Dmx like 1" Q9Y485 5 119037772-119249138 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Prostatic glandular cells: 1370.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Prostate glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036431, HPA036432" Approved Approved "Nucleoli,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 32: Basophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 30: White matter - Myelination" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 17 "Nucleoli, Nucleoli fibrillar center" Cytosol "HPA036431: , HPA036432: " "unprognostic (1.77e-1)" "unprognostic (1.41e-1)" "unprognostic (8.80e-2)" "unprognostic (1.61e-1)" "unprognostic (1.80e-1)" "unprognostic (1.79e-1)" "unprognostic (2.53e-1)" "unprognostic (2.34e-1)" "unprognostic (1.21e-1)" "potential prognostic unfavorable (3.99e-4)" "potential prognostic favorable (1.96e-8)" "unprognostic (3.73e-3)" "unprognostic (1.06e-1)" "unprognostic (2.44e-1)" "unprognostic (4.04e-2)" "unprognostic (1.65e-2)" "unprognostic (1.95e-1)" "unprognostic (5.99e-2)" "unprognostic (2.53e-2)" "potential prognostic unfavorable (7.00e-4)" "unprognostic (1.59e-3)" "unprognostic (2.00e-2)" "unprognostic (2.63e-2)" "unprognostic (1.40e-1)" "unprognostic (1.39e-1)" "unprognostic (1.09e-2)" "unprognostic (2.08e-1)" "unprognostic (1.22e-1)" "unprognostic (7.31e-2)" "unprognostic (3.88e-3)" "unprognostic (3.10e-2)" DMXL2 "DFNA71, KIAA0856, RC3" ENSG00000104093 "Dmx like 2" Q8TDJ6 15 51447711-51622833 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Deafness, Diabetes mellitus, Disease variant, Epilepsy, Hypogonadotropic hypogonadism, Neuropathy, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Kupffer cells: 443.8;Macrophages: 286.4;Monocyte progenitors: 331.4;monocytes: 733.1;Neutrophil progenitors: 364.3;Neutrophils: 691.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "classical monocyte: 2.8;intermediate monocyte: 2.2;neutrophil: 2.2;non-classical monocyte: 2.7" "Group enriched" "Detected in many" 4 "granulocytes: 2.2;monocytes: 2.8" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Smooth muscle cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039375, CAB080713, CAB080714" Approved Supported Vesicles,Cytosol NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 40: Non-specific - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 14 Vesicles Cytosol "CAB080713: , CAB080714: , HPA039375: " "unprognostic (1.61e-2)" "unprognostic (7.89e-2)" "unprognostic (9.19e-2)" "unprognostic (3.70e-2)" "unprognostic (5.77e-2)" "unprognostic (1.82e-1)" "unprognostic (1.55e-1)" "unprognostic (1.48e-2)" "unprognostic (3.71e-1)" "unprognostic (2.73e-3)" "unprognostic (4.48e-3)" "unprognostic (4.53e-2)" "unprognostic (1.92e-1)" "unprognostic (1.08e-1)" "unprognostic (7.57e-2)" "unprognostic (2.19e-1)" "unprognostic (1.07e-1)" "unprognostic (3.86e-1)" "unprognostic (4.84e-3)" "unprognostic (6.16e-3)" "unprognostic (3.90e-1)" "unprognostic (1.58e-3)" "unprognostic (1.23e-1)" "unprognostic (4.77e-2)" "unprognostic (1.54e-2)" "unprognostic (1.83e-1)" "unprognostic (1.89e-1)" "unprognostic (1.44e-1)" "unprognostic (2.22e-2)" "unprognostic (1.06e-2)" DNA2 "DNA2L, KIAA0083" ENSG00000138346 "DNA replication helicase/nuclease 2" P51530 10 68414064-68472121 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication" "DNA-binding, Endonuclease, Helicase, Hydrolase, Multifunctional enzyme, Nuclease" "Disease variant, Dwarfism, Ectodermal dysplasia, Hypotrichosis, Intellectual disability, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 7.6" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 44.6;Erythrocyte progenitors: 102.5;Megakaryocyte progenitors: 70.7;Monocyte progenitors: 63.6;Neutrophil progenitors: 58.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "NK-cell: 1.9" "Lineage enriched" "Detected in single" 5 "NK-cells: 1.9" "Low cancer specificity" "Detected in all" "Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA037487, HPA057526" Approved Supported Mitochondria No Yes "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 34: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 27: Non-specific - Cell proliferation" 23 Mitochondria "HPA037487: , HPA057526: " "unprognostic (1.31e-2)" "unprognostic (2.17e-1)" "unprognostic (1.75e-2)" "unprognostic (2.67e-1)" "unprognostic (1.39e-2)" "unprognostic (1.39e-1)" "unprognostic (1.13e-1)" "potential prognostic favorable (3.84e-4)" "unprognostic (3.23e-3)" "potential prognostic unfavorable (3.38e-6)" "unprognostic (1.03e-2)" "unprognostic (7.39e-2)" "potential prognostic unfavorable (7.11e-5)" "unprognostic (3.61e-1)" "potential prognostic unfavorable (8.26e-4)" "unprognostic (1.44e-2)" "unprognostic (9.28e-2)" "unprognostic (6.42e-2)" "unprognostic (1.52e-1)" "unprognostic (3.11e-1)" "unprognostic (6.09e-2)" "potential prognostic unfavorable (8.63e-4)" "unprognostic (5.20e-2)" "unprognostic (1.69e-2)" "unprognostic (1.11e-1)" "unprognostic (1.54e-1)" "unprognostic (1.36e-1)" "unprognostic (3.24e-1)" "unprognostic (1.26e-1)" DNAAF1 "CILD13, DAU1, FLJ25330, LRRC50, ODA7, swt" ENSG00000154099 "Dynein axonemal assembly factor 1" Q8NEP3 16 84145287-84178767 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 23.0;fallopian tube: 21.4;testis: 42.3" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 156.3;Endometrial ciliated cells: 459.5;Ependymal cells: 656.2;Epididymal efferent duct ciliated cells: 312.7;Fallopian tube ciliated cells: 415.2;Late primary spermatocytes: 187.4;Plasma cells: 146.9;Respiratory ciliated cells: 768.5" "Cell type enriched" "Detected in many" 6 "ependymal cell: 686.0" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 38.8" "Group enriched" "Detected in many" 6 "choroid plexus: 18.4;medulla oblongata: 7.5;midbrain: 13.3;pons: 6.6;spinal cord: 4.6" "Immune cell enhanced" "Detected in some" "neutrophil: 2.0" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in single" "Myeloma: 1.0" "Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA074239 Enhanced NA NA "Cluster 32: Basophils - Transcription" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 35: RS4;11 - Unknown function" "Cluster 78: Plasma cells - Antibody production & ER-stress response" 5 "HPA074239: " "unprognostic (1.79e-1)" "unprognostic (5.97e-2)" "unprognostic (8.31e-2)" "unprognostic (7.80e-3)" "unprognostic (2.73e-2)" "unprognostic (1.40e-2)" "unprognostic (4.81e-1)" "unprognostic (3.09e-3)" "unprognostic (4.32e-2)" "unprognostic (8.35e-3)" "unprognostic (3.31e-1)" "unprognostic (1.70e-2)" "unprognostic (2.91e-3)" "unprognostic (1.74e-2)" "potential prognostic unfavorable (4.78e-4)" "unprognostic (3.97e-2)" "unprognostic (1.64e-1)" "unprognostic (1.34e-1)" "unprognostic (1.34e-3)" "unprognostic (5.59e-2)" DNAAF10 "FLJ31741, Monad, WDR92" ENSG00000243667 "Dynein axonemal assembly factor 10" Q96MX6 2 68122936-68157549 "Essential proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ependymal cells: 55.4;Epididymal efferent duct ciliated cells: 45.7;Fallopian tube ciliated cells: 60.5;Respiratory ciliated cells: 68.4" "Cell type enhanced" "Detected in all" "ependymal cell: 65.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035335, HPA035336" Approved NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 22: Epididymis - Mixed function" "Cluster 17: Choroid plexus - Cilium" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 34: Ciliated cells - Cilia assembly & function" 69 "HPA035335: , HPA035336: " "unprognostic (4.51e-2)" "unprognostic (1.46e-2)" "unprognostic (2.35e-1)" "unprognostic (4.06e-2)" "unprognostic (1.91e-1)" "unprognostic (4.15e-2)" "unprognostic (2.26e-1)" "unprognostic (3.08e-1)" "unprognostic (4.91e-2)" "unprognostic (4.01e-2)" "unprognostic (1.67e-2)" "unprognostic (1.56e-1)" "unprognostic (6.21e-2)" "potential prognostic unfavorable (1.12e-4)" "unprognostic (6.62e-2)" "unprognostic (4.62e-2)" "unprognostic (1.05e-1)" "unprognostic (5.72e-3)" "unprognostic (2.91e-2)" "unprognostic (6.40e-2)" "unprognostic (4.65e-2)" "unprognostic (1.10e-1)" "unprognostic (1.40e-1)" "unprognostic (1.19e-1)" "unprognostic (1.77e-2)" "unprognostic (2.61e-1)" "unprognostic (1.28e-1)" "unprognostic (2.69e-1)" "unprognostic (3.39e-2)" "unprognostic (6.93e-2)" "unprognostic (6.94e-2)" DNAAF11 "CILD19, LRRC6, LRTP, tilB, TSLRP" ENSG00000129295 "Dynein axonemal assembly factor 11" Q86X45 8 132570416-132675592 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 46.5;testis: 24.5" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 315.3;Early spermatids: 189.2;Endometrial ciliated cells: 266.9;Ependymal cells: 440.4;Epididymal efferent duct ciliated cells: 207.8;Fallopian tube ciliated cells: 261.4;Late primary spermatocytes: 361.0;Respiratory ciliated cells: 397.1" "Cell type enhanced" "Detected in all" "ependymal cell: 485.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 2.5" "Lineage enriched" "Detected in single" 8 "granulocytes: 2.5" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 8.9" "Colon - Enteric glia cells, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA028043, HPA028058" Approved Approved "Mid piece,Principal piece" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" 9 "Mid piece, Principal piece" "HPA028043: , HPA028058: " "potential prognostic favorable (9.58e-5)" "unprognostic (1.67e-2)" "unprognostic (5.34e-2)" "unprognostic (1.07e-1)" "unprognostic (2.40e-1)" "unprognostic (2.58e-2)" "unprognostic (3.83e-2)" "unprognostic (8.45e-2)" "unprognostic (3.42e-2)" "unprognostic (1.68e-1)" "unprognostic (2.16e-1)" "unprognostic (1.23e-1)" "unprognostic (3.93e-3)" "unprognostic (1.94e-1)" "unprognostic (3.75e-2)" "unprognostic (1.24e-1)" "unprognostic (1.19e-1)" "unprognostic (6.73e-2)" "unprognostic (1.27e-1)" "unprognostic (2.04e-1)" "unprognostic (1.11e-1)" "unprognostic (3.91e-3)" "unprognostic (1.61e-1)" "unprognostic (1.02e-1)" "unprognostic (1.27e-1)" "unprognostic (4.49e-2)" "unprognostic (2.96e-2)" "unprognostic (3.82e-2)" "potential prognostic unfavorable (5.27e-4)" "unprognostic (2.15e-1)" DNAAF2 "C14orf104, CILD10, FLJ10563, KTU, PF13" ENSG00000165506 "Dynein axonemal assembly factor 2" Q9NVR5 14 49625174-49635244 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002894, HPA004113" Enhanced Approved "Nucleoli,Golgi apparatus,Primary cilium,Basal body,Cytosol" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 76: Non-specific - Metabolism" "Cluster 46: Brainstem - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 8 "Basal body, Cytosol" "Nucleoli, Golgi apparatus, Primary cilium" "HPA002894: , HPA004113: " "unprognostic (9.48e-2)" "unprognostic (2.05e-1)" "unprognostic (1.73e-1)" "unprognostic (1.05e-1)" "unprognostic (6.51e-3)" "unprognostic (2.90e-3)" "unprognostic (1.15e-2)" "unprognostic (2.15e-1)" "unprognostic (4.28e-2)" "potential prognostic favorable (8.49e-7)" "unprognostic (4.13e-3)" "unprognostic (2.34e-1)" "unprognostic (3.15e-2)" "unprognostic (1.66e-1)" "unprognostic (5.33e-1)" "unprognostic (2.14e-1)" "unprognostic (1.42e-2)" "unprognostic (1.99e-1)" "unprognostic (2.55e-1)" "unprognostic (1.51e-1)" "unprognostic (2.32e-1)" "unprognostic (7.55e-2)" "unprognostic (3.89e-2)" "potential prognostic favorable (8.18e-4)" "unprognostic (5.05e-2)" "unprognostic (5.78e-2)" "unprognostic (2.97e-1)" "unprognostic (3.24e-1)" "unprognostic (1.37e-2)" "unprognostic (1.66e-3)" DNAAF3 "C19orf51, CILD2, FLJ36139, FLJ40069, PCD, PF22" ENSG00000167646 "Dynein axonemal assembly factor 3" Q8N9W5 19 55158661-55166722 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "fallopian tube: 38.3;testis: 61.4" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 99.5;Early spermatids: 51.5;Endometrial ciliated cells: 10.8;Ependymal cells: 23.6;Fallopian tube ciliated cells: 24.6;Late primary spermatocytes: 10.6;Late spermatids: 10.6;Respiratory ciliated cells: 50.7;Respiratory deuterosomal cells: 14.5" "Cell type enriched" "Detected in some" 5 "ependymal cell: 23.9" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 15.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043222 Approved Vesicles,Cytosol NA No "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 47: Leukemia - Hemostasis" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 1 Cytosol Vesicles "HPA043222: " "unprognostic (2.39e-1)" "unprognostic (9.92e-2)" "unprognostic (7.19e-2)" "unprognostic (3.09e-1)" "unprognostic (2.38e-1)" "unprognostic (4.23e-2)" "unprognostic (2.55e-3)" "unprognostic (2.35e-1)" "unprognostic (5.16e-3)" "unprognostic (1.65e-1)" "potential prognostic favorable (5.05e-4)" "unprognostic (1.82e-1)" "unprognostic (1.30e-2)" "unprognostic (1.25e-1)" "unprognostic (2.88e-1)" "unprognostic (5.53e-2)" "unprognostic (2.53e-1)" "unprognostic (2.00e-2)" "unprognostic (3.59e-1)" "unprognostic (8.10e-3)" "unprognostic (5.51e-3)" "unprognostic (1.52e-1)" "unprognostic (2.40e-2)" "unprognostic (9.97e-2)" DNAAF4 "CILD25, DYX1C1, EKN1, FLJ37882" ENSG00000256061 "Dynein axonemal assembly factor 4" Q8WXU2 15 55410525-55508234 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Neurogenesis "Ciliopathy, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 27.4" "Cell type enhanced" "Detected in many" "Astrocytes: 39.0;Bergmann glia: 48.0;Brain excitatory neurons: 41.6;Brain inhibitory neurons: 51.1;Choroid plexus epithelial cells: 125.8;Distal convoluted tubule cells: 48.1;Endometrial ciliated cells: 33.9;Ependymal cells: 195.6;Loop of henle epithelial cells: 51.9;Other brain neurons: 68.0;Papillary tip epithelial cells: 39.2;Podocytes: 42.6;Proximal tubule cells: 56.3;Renal collecting duct principal cells: 71.9;Renal connecting tubule cells: 51.8" "Cell type enhanced" "Detected in all" "ependymal cell: 201.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051048, HPA070577" Uncertain Supported "Plasma membrane,Cytosol,Connecting piece,Mid piece,Principal piece" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" 7 "Cytosol, Mid piece" "Plasma membrane, Connecting piece, Principal piece" "HPA051048: , HPA070577: " "unprognostic (4.70e-2)" "unprognostic (1.24e-2)" "unprognostic (4.63e-2)" "unprognostic (9.11e-2)" "unprognostic (4.12e-2)" "unprognostic (2.67e-1)" "unprognostic (4.42e-2)" "unprognostic (1.38e-1)" "potential prognostic unfavorable (4.11e-4)" "unprognostic (1.63e-1)" "unprognostic (1.95e-1)" "potential prognostic favorable (8.78e-4)" "potential prognostic unfavorable (1.45e-4)" "unprognostic (2.69e-2)" "unprognostic (9.61e-2)" "unprognostic (6.01e-2)" "unprognostic (1.32e-1)" "unprognostic (5.11e-2)" "unprognostic (2.16e-1)" "unprognostic (9.34e-2)" "unprognostic (3.49e-3)" "unprognostic (1.42e-1)" "unprognostic (1.31e-1)" "unprognostic (1.24e-1)" "unprognostic (2.59e-2)" "unprognostic (1.43e-2)" "unprognostic (1.64e-1)" "unprognostic (2.65e-1)" "unprognostic (6.83e-3)" DNAAF5 "CILD18, FLJ20397, FLJ25564, FLJ31671, FLJ39381, HEATR2" ENSG00000164818 "Dynein axonemal assembly factor 5" Q86Y56 7 726699-786475 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 76.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020243, HPA060196" Uncertain Supported Nucleoli,Microtubules,Cytosol NA NA 4600 "Cluster 33: Non-specific - ATP binding" "Cluster 24: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 67: Non-specific - Unknown function" "Cluster 34: Ciliated cells - Cilia assembly & function" 27 Cytosol "Nucleoli, Microtubules" "HPA020243: , HPA060196: " "unprognostic (1.01e-1)" "unprognostic (2.04e-2)" "unprognostic (8.13e-3)" "unprognostic (1.66e-1)" "unprognostic (4.86e-2)" "unprognostic (6.41e-2)" "unprognostic (6.64e-3)" "unprognostic (1.08e-3)" "unprognostic (6.04e-3)" "potential prognostic favorable (9.00e-4)" "unprognostic (1.77e-1)" "unprognostic (5.23e-3)" "unprognostic (2.79e-3)" "unprognostic (1.84e-3)" "potential prognostic unfavorable (4.29e-4)" "unprognostic (1.32e-1)" "unprognostic (5.99e-2)" "unprognostic (3.83e-2)" "unprognostic (1.46e-1)" "unprognostic (9.62e-2)" "unprognostic (3.69e-3)" "unprognostic (6.81e-3)" "unprognostic (9.44e-3)" "unprognostic (8.05e-2)" "unprognostic (2.24e-1)" "unprognostic (1.18e-1)" "unprognostic (3.24e-1)" "unprognostic (1.14e-1)" "unprognostic (3.25e-2)" DNAAF6 "CXorf41, MGC35261, NYSAR97, PIH1D3, TWISTER" ENSG00000080572 "Dynein axonemal assembly factor 6" Q9NQM4 X 107206611-107244247 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "choroid plexus: 3.8;fallopian tube: 10.2;testis: 11.1" "Cell type enhanced" "Detected in some" "Early spermatids: 174.4;Endometrial ciliated cells: 61.1;Ependymal cells: 32.7;Epididymal efferent duct ciliated cells: 40.3;Fallopian tube ciliated cells: 97.0;Late primary spermatocytes: 147.7;Respiratory ciliated cells: 150.0" "Cell type enriched" "Detected in some" 8 "ependymal cell: 45.9" "Cancer enhanced" "Detected in single" "Uterine Corpus Endometrial Carcinoma (TCGA): 1.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in single" "Region enhanced" "Detected in some" "midbrain: 4.0" "HPA051099, HPA072496" Enhanced Approved "Nucleoplasm,Golgi apparatus,Primary cilium,Primary cilium tip,Basal body,Cytosol,Acrosome,Equatorial segment" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 107: Ciliated cells - Cilia assembly & function" 11 "Golgi apparatus, Primary cilium, Acrosome" "Nucleoplasm, Primary cilium tip, Basal body, Cytosol, Equatorial segment" "HPA051099: , HPA072496: " "unprognostic (2.45e-1)" DNAAF8 "C16orf71, DKFZp686H2240, FLJ43261" ENSG00000166246 "Dynein axonemal assembly factor 8" Q8IYS4 16 4734344-4749396 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "fallopian tube: 21.2;testis: 73.8" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 45.0;Early spermatids: 30.5;Ependymal cells: 38.9;Epididymal efferent duct ciliated cells: 38.6;Fallopian tube ciliated cells: 50.2;Late primary spermatocytes: 241.7;Late spermatids: 98.6;Respiratory ciliated cells: 68.4" "Group enriched" "Detected in many" 10 "choroid plexus epithelial cell: 17.0;ependymal cell: 49.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" HPA049468 Enhanced NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 27: Breast cancer - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" "HPA049468: " "unprognostic (1.60e-1)" "unprognostic (3.18e-2)" "unprognostic (6.63e-2)" "unprognostic (1.88e-3)" "unprognostic (1.61e-1)" "unprognostic (1.20e-2)" "unprognostic (1.24e-1)" "unprognostic (2.85e-2)" "unprognostic (1.23e-1)" "unprognostic (1.23e-1)" "unprognostic (8.32e-3)" "unprognostic (1.42e-1)" "unprognostic (3.18e-1)" "unprognostic (3.11e-1)" "unprognostic (2.65e-1)" "unprognostic (1.09e-1)" "unprognostic (1.24e-1)" "unprognostic (6.12e-3)" "unprognostic (2.04e-1)" "unprognostic (1.06e-1)" "unprognostic (4.87e-1)" "unprognostic (8.90e-2)" "unprognostic (1.15e-1)" "potential prognostic unfavorable (1.68e-5)" "unprognostic (1.68e-2)" DNAAF9 "C20orf194, DKFZp434N061" ENSG00000088854 "Dynein axonemal assembly factor 9" Q5TEA3 20 3249306-3407669 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 486.5;Distal convoluted tubule cells: 653.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Prostate - Smooth muscle cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052103, HPA067418" Approved Approved "Nucleoli fibrillar center,Cytosol" No No "Cluster 2: Dendritic cells - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" "Nucleoli fibrillar center, Cytosol" "HPA052103: , HPA067418: " "unprognostic (4.89e-2)" "unprognostic (1.00e-1)" "unprognostic (1.13e-2)" "unprognostic (5.40e-2)" "unprognostic (1.40e-2)" "unprognostic (7.17e-2)" "unprognostic (1.57e-1)" "unprognostic (6.46e-2)" "unprognostic (7.77e-2)" "unprognostic (1.41e-1)" "potential prognostic favorable (4.35e-5)" "unprognostic (1.13e-3)" "unprognostic (2.66e-1)" "unprognostic (8.53e-3)" "unprognostic (1.60e-1)" "unprognostic (2.19e-2)" "unprognostic (6.87e-2)" "unprognostic (1.86e-3)" "unprognostic (5.82e-2)" "unprognostic (3.71e-2)" "unprognostic (6.92e-2)" "unprognostic (1.83e-3)" "unprognostic (2.92e-3)" "unprognostic (2.86e-1)" "unprognostic (6.64e-3)" "unprognostic (1.25e-2)" "unprognostic (1.19e-1)" "unprognostic (1.91e-2)" "unprognostic (2.76e-1)" "unprognostic (1.27e-1)" "unprognostic (4.29e-3)" DNAH1 "DNAHC1, HDHC7, HL-11, HL11, XLHSRF-1" ENSG00000114841 "Dynein axonemal heavy chain 1" Q9P2D7 3 52316319-52400492 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Motor protein" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ependymal cells: 106.7;Respiratory ciliated cells: 101.1;Tuft cells: 46.1" "Cell type enriched" "Detected in all" 4 "ependymal cell: 106.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" "Region enhanced" "Detected in many" "midbrain: 4.6" "HPA036805, HPA036806" Uncertain NA NA "Cluster 44: Bone marrow - Nuclear processes" "Cluster 17: Choroid plexus - Cilium" "Cluster 6: Leukemia - Signal transduction" "Cluster 34: Ciliated cells - Cilia assembly & function" 1 "HPA036805: , HPA036806: " "unprognostic (1.71e-3)" "unprognostic (2.57e-2)" "potential prognostic favorable (4.22e-4)" "unprognostic (1.34e-1)" "potential prognostic favorable (2.72e-4)" "unprognostic (5.56e-3)" "unprognostic (7.56e-3)" "unprognostic (9.72e-2)" "unprognostic (1.99e-1)" "unprognostic (7.85e-3)" "unprognostic (1.17e-1)" "unprognostic (5.04e-2)" DNAH10 FLJ43808 ENSG00000197653 "Dynein axonemal heavy chain 10" Q8IVF4 12 123762188-123935720 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Motor protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 3.2;testis: 2.8" "Group enriched" "Detected in many" 4 "Endometrial ciliated cells: 99.6;Ependymal cells: 315.7;Fallopian tube ciliated cells: 118.4;Late spermatids: 109.9;Respiratory ciliated cells: 227.4" "Cell type enriched" "Detected in many" 14 "ependymal cell: 335.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA039066 Enhanced Supported "Principal piece" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 70: DU4475 - Unknown function" "Cluster 34: Ciliated cells - Cilia assembly & function" 2 "Principal piece" "HPA039066: " "potential prognostic favorable (4.65e-4)" "unprognostic (2.73e-2)" DNAH11 "CILD7, DNAHBL, Dnahc11, DNHBL, DPL11" ENSG00000105877 "Dynein axonemal heavy chain 11" Q96DT5 7 21543039-21901839 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Motor protein" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "parathyroid gland: 66.9" "Group enriched" "Detected in many" 4 "Cardiomyocytes: 555.8;Choroid plexus epithelial cells: 1446.0;Endometrial ciliated cells: 1106.0;Ependymal cells: 1709.9;Epididymal efferent duct ciliated cells: 797.9;Fallopian tube ciliated cells: 876.6;Respiratory ciliated cells: 1700.4;Thymic myoid cells: 688.0" "Group enriched" "Detected in many" 12 "choroid plexus epithelial cell: 1068.8;ependymal cell: 1766.4" "Cancer enhanced" "Detected in some" "Kidney Renal Clear Cell Carcinoma (TCGA): 4.0;Uterine Corpus Endometrial Carcinoma (TCGA): 3.2" "Region enhanced" "Detected in many" "choroid plexus: 75.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adrenal gland - Adrenal cortex cells, Lung - Respiratory ciliated cells, Prostate - Prostate basal glandular cells" "Not detected" "Not detected" "Region enhanced" "Detected in many" "midbrain: 8.6" "HPA045880, HPA056474" Approved NA NA "Cluster 69: Parathyroid gland - Mixed function" "Cluster 3: Choroid plexus - Cilium" "Cluster 15: Kidney cancer - Membrane components" "Cluster 34: Ciliated cells - Cilia assembly & function" 1 "HPA045880: , HPA056474: " "potential prognostic unfavorable (1.01e-4)" "unprognostic (5.02e-2)" "unprognostic (2.38e-2)" "potential prognostic unfavorable (2.16e-5)" "unprognostic (6.86e-2)" "unprognostic (1.30e-2)" "unprognostic (5.76e-2)" "potential prognostic unfavorable (1.46e-6)" "unprognostic (2.48e-1)" DNAH12 "DHC3, DLP12, DNAH12L, DNAH7L, Dnahc3, DNHD2, FLJ40427, FLJ44290, hdhc3, HL-19" ENSG00000174844 "Dynein axonemal heavy chain 12" Q6ZR08 3 57293699-57544344 "Cancer-related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Motor protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "choroid plexus: 8.7;fallopian tube: 9.7;lung: 3.5;testis: 8.4" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 457.4;Endometrial ciliated cells: 1090.3;Ependymal cells: 1304.3;Epididymal efferent duct ciliated cells: 350.9;Fallopian tube ciliated cells: 851.1;Respiratory ciliated cells: 2668.6;Respiratory deuterosomal cells: 235.3" "Group enriched" "Detected in all" 31 "choroid plexus epithelial cell: 367.3;ependymal cell: 1354.1" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 3.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA037493, HPA058203, HPA061365" Enhanced Approved "Centrosome,Cytosol,Mid piece,Principal piece" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 32: Non-specific - Cell proliferation" "Cluster 107: Ciliated cells - Cilia assembly & function" "Centrosome, Mid piece, Principal piece" Cytosol "HPA037493: , HPA058203: , HPA061365: " "unprognostic (8.72e-2)" "unprognostic (7.26e-2)" "unprognostic (6.43e-2)" "unprognostic (1.24e-2)" DNAH14 "C1orf67, DKFZp781B1548, Dnahc14, HL-18, HL18, MGC27277" ENSG00000185842 "Dynein axonemal heavy chain 14" Q0VDD8 1 224896262-225399292 "Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 18.5" "Cell type enhanced" "Detected in many" "Early spermatids: 359.7;Gonadotrophs: 374.6;Lactotrophs: 479.0;Retinal amacrine cells: 372.0;Somatotrophs: 438.7;Thyrotrophs: 448.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA027718, HPA028545, HPA031379" Uncertain Approved "Golgi apparatus,Centrosome,Basal body" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 21: Testis - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" "Centrosome, Basal body" "Golgi apparatus" "HPA027718: , HPA028545: , HPA031379: " "unprognostic (1.25e-3)" "unprognostic (3.52e-1)" "unprognostic (5.20e-1)" "unprognostic (7.45e-2)" "unprognostic (2.71e-1)" "unprognostic (1.58e-1)" "unprognostic (1.04e-1)" "unprognostic (1.42e-3)" "unprognostic (2.90e-2)" "validated prognostic unfavorable (9.46e-6)" "validated prognostic unfavorable (1.08e-4)" "unprognostic (1.84e-1)" "potential prognostic unfavorable (3.92e-4)" "unprognostic (1.94e-2)" "unprognostic (1.77e-3)" "unprognostic (5.88e-3)" "unprognostic (2.87e-3)" "unprognostic (1.39e-1)" "unprognostic (9.06e-3)" "unprognostic (4.06e-1)" "unprognostic (5.96e-2)" "unprognostic (4.48e-3)" "unprognostic (2.19e-2)" "unprognostic (2.56e-1)" "unprognostic (1.29e-1)" "unprognostic (1.31e-1)" "unprognostic (3.11e-2)" "unprognostic (1.87e-1)" "unprognostic (4.36e-2)" "unprognostic (4.93e-2)" DNAH17 "DNAHL1, DNEL2, FLJ40457" ENSG00000187775 "Dynein axonemal heavy chain 17" Q9UFH2 17 78423697-78577396 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Motor protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "retina: 2.3;testis: 5.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 223.6;Early spermatids: 69.5;Late primary spermatocytes: 58.8;Late spermatids: 59.3;monocytes: 43.9;Neutrophils: 94.8;Retinal bipolar cells: 312.1" "Cell type enriched" "Detected in all" 5 "oligodendrocyte: 76.5" "Cancer enhanced" "Detected in single" "Head and Neck Squamous Cell Carcinoma (TCGA): 2.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Endothelial cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA024354, HPA076261" Enhanced Supported "Mid piece,Principal piece,End piece" NA NA "Cluster 47: Testis - Mixed function" "Cluster 30: White matter - Myelination" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 1 "Mid piece, Principal piece, End piece" "HPA024354: , HPA076261: " "unprognostic (7.19e-3)" "unprognostic (2.57e-2)" "unprognostic (7.35e-2)" "potential prognostic unfavorable (1.08e-4)" DNAH2 "DNHD3, FLJ46675, KIAA1503" ENSG00000183914 "Dynein axonemal heavy chain 2" Q9P225 17 7717744-7833742 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Motor protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "fallopian tube: 12.3;parathyroid gland: 9.9;retina: 19.2;testis: 6.2" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 56.8;Ependymal cells: 204.4;Epicardial cells: 38.7;Epididymal efferent duct ciliated cells: 44.1;Fallopian tube ciliated cells: 108.0;Respiratory ciliated cells: 255.2;Rod photoreceptor cells: 256.5" "Cell type enriched" "Detected in all" 6 "ependymal cell: 211.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatic stellate cells, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA067103 Enhanced Approved "Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Basal body,Flagellar centriole,End piece" Yes NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 79: Photoreceptor cells - Phototransduction" 4 "Microtubules, Primary cilium, Flagellar centriole, End piece" "Cytokinetic bridge, Mitotic spindle, Basal body" "HPA067103: " "unprognostic (1.19e-2)" "unprognostic (5.47e-2)" "unprognostic (1.28e-1)" "unprognostic (5.56e-2)" "unprognostic (1.80e-1)" "unprognostic (2.12e-1)" "unprognostic (5.00e-2)" "unprognostic (1.33e-2)" "unprognostic (1.83e-1)" "unprognostic (1.71e-1)" "unprognostic (1.25e-1)" "unprognostic (7.56e-3)" "unprognostic (1.68e-1)" "unprognostic (3.29e-1)" "potential prognostic unfavorable (5.90e-4)" "unprognostic (3.24e-1)" "unprognostic (2.68e-1)" DNAH3 "DKFZp434N074, DLP3, Dnahc3b, Hsadhc3" ENSG00000158486 "Dynein axonemal heavy chain 3" Q8TD57 16 20933111-21159441 "Plasma proteins, Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "fallopian tube: 5.1;testis: 3.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 96.6;Early spermatids: 202.5;Endometrial ciliated cells: 284.6;Ependymal cells: 459.8;Epididymal efferent duct ciliated cells: 121.7;Fallopian tube ciliated cells: 315.7;Late primary spermatocytes: 87.1;Respiratory ciliated cells: 900.1" "Cell type enriched" "Detected in many" 57 "ependymal cell: 467.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA056212, HPA062493" Approved "Equatorial segment,Flagellar centriole,Mid piece,Principal piece" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 107: Ciliated cells - Cilia assembly & function" 1 "Mid piece, Principal piece" "Equatorial segment, Flagellar centriole" "HPA056212: , HPA062493: " "unprognostic (4.03e-1)" "unprognostic (1.09e-1)" "unprognostic (1.91e-1)" DNAH5 "CILD3, Dnahc5, HL1, KTGNR, PCD" ENSG00000039139 "Dynein axonemal heavy chain 5" Q8TE73 5 13690328-14011818 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Motor protein" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 2.8;fallopian tube: 3.3" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 1053.8;Ependymal cells: 552.3;Epididymal efferent duct ciliated cells: 436.5;Fallopian tube ciliated cells: 966.5;Respiratory ciliated cells: 1951.6;Respiratory deuterosomal cells: 285.1;Somatotrophs: 388.4" "Group enriched" "Detected in many" 10 "choroid plexus epithelial cell: 199.8;ependymal cell: 607.6" "Cancer enhanced" "Detected in some" "Prostate Adenocarcinoma (TCGA): 3.9" "Region enhanced" "Detected in all" "choroid plexus: 28.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Somatotropes, Prostate - Prostate glandular cells, Testis - Spermatogonia" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA037469, HPA037470" Enhanced NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 107: Ciliated cells - Cilia assembly & function" 1 "HPA037469: , HPA037470: " "unprognostic (3.34e-1)" "unprognostic (5.85e-2)" "unprognostic (4.76e-2)" "unprognostic (2.00e-1)" "unprognostic (1.30e-3)" "unprognostic (1.63e-2)" "unprognostic (2.94e-2)" "unprognostic (1.12e-2)" "unprognostic (2.14e-1)" "potential prognostic unfavorable (8.91e-4)" "unprognostic (5.91e-2)" DNAH6 "Dnahc6, DNHL1, FLJ37357, HL-2" ENSG00000115423 "Dynein axonemal heavy chain 6" Q9C0G6 2 84516455-84819589 "Plasma proteins, Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 5.0;fallopian tube: 5.1" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 1073.6;Corticotrophs: 299.0;Endometrial ciliated cells: 537.7;Ependymal cells: 1671.8;Epididymal efferent duct ciliated cells: 371.4;Fallopian tube ciliated cells: 649.1;Respiratory ciliated cells: 1137.5" "Group enriched" "Detected in all" 4 "choroid plexus epithelial cell: 779.6;ependymal cell: 1841.5" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA036391, HPA061401" Enhanced Approved "Plasma membrane,Primary cilium tip,Centriolar satellite,Basal body,Calyx,Connecting piece,Mid piece" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 34: Ciliated cells - Cilia assembly & function" 4 "Plasma membrane, Centriolar satellite, Basal body, Connecting piece, Mid piece" "Primary cilium tip, Calyx" "HPA036391: , HPA061401: " "unprognostic (2.55e-2)" "unprognostic (2.21e-1)" "unprognostic (7.02e-3)" "unprognostic (1.29e-1)" "unprognostic (2.35e-2)" "unprognostic (5.24e-2)" DNAH7 KIAA0944 ENSG00000118997 "Dynein axonemal heavy chain 7" Q8WXX0 2 195737703-196068837 "Plasma proteins, Predicted intracellular proteins" "Motor protein" "Ciliopathy, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 19.8;testis: 10.3" "Cell type enhanced" "Detected in many" "Astrocytes: 361.4;Choroid plexus epithelial cells: 1118.9;Endometrial ciliated cells: 860.4;Ependymal cells: 1863.8;Epididymal efferent duct ciliated cells: 576.7;Fallopian tube ciliated cells: 737.9;Respiratory ciliated cells: 1361.5;Somatotrophs: 327.9" "Group enriched" "Detected in all" 4 "choroid plexus epithelial cell: 912.2;ependymal cell: 2037.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Testis - Early spermatids" "Not detected" "Not detected" "Region enhanced" "Detected in many" "midbrain: 5.9" "HPA034724, HPA044070" Enhanced Supported "Vesicles,Cytosol,Mid piece,Annulus" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 50: Lymphoma - Unknown function" "Cluster 34: Ciliated cells - Cilia assembly & function" "Mid piece, Annulus" "Vesicles, Cytosol" "HPA034724: , HPA044070: " "unprognostic (3.38e-1)" "unprognostic (2.06e-1)" "unprognostic (5.54e-3)" "unprognostic (2.80e-3)" "unprognostic (2.82e-1)" "unprognostic (1.61e-1)" "unprognostic (1.87e-2)" "unprognostic (1.81e-2)" "unprognostic (2.95e-3)" "unprognostic (9.36e-2)" "unprognostic (1.29e-1)" "unprognostic (2.64e-1)" "unprognostic (1.80e-2)" "unprognostic (2.57e-2)" "unprognostic (3.43e-2)" "unprognostic (9.53e-2)" "unprognostic (1.09e-2)" "unprognostic (6.66e-2)" "unprognostic (3.14e-2)" DNAH8 hdhc9 ENSG00000124721 "Dynein axonemal heavy chain 8" Q96JB1 6 38715311-39030792 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Motor protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 2.4;prostate: 2.0;testis: 7.3" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 36.3;Early primary spermatocytes: 66.0;Early spermatids: 30.0;Foveolar cells: 29.9;Late primary spermatocytes: 85.4;Late spermatids: 20.9;Plasma cells: 16.2;Prostatic glandular cells: 28.2;Undifferentiated spermatogonia: 42.2" "Cell type enhanced" "Detected in many" "eccentric medium spiny neuron: 23.4;hippocampal dentate gyrus: 13.6" "Cancer enriched" "Detected in single" 10 "Prostate Adenocarcinoma (TCGA): 7.6" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 8 "basophil: 2.5" "Lineage enriched" "Detected in single" 8 "granulocytes: 2.5" "Cancer enhanced" "Detected in single" "prostate cancer: 2.5" "Spleen - Endothelial cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA028447, HPA030108, HPA030109" Uncertain Enhanced "Mid piece,Principal piece" NA NA "Cluster 32: Basophils - Transcription" "Cluster 22: Epididymis - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 1 "Mid piece, Principal piece" "HPA028447: , HPA030108: , HPA030109: " "unprognostic (1.98e-1)" DNAH9 "DNAH17L, Dnahc9, DNAL1, DYH9, HL-20, HL20, KIAA0357" ENSG00000007174 "Dynein axonemal heavy chain 9" Q9NYC9 17 11598470-11969748 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Motor protein" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 13.5;choroid plexus: 11.9;fallopian tube: 33.1" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 346.2;Endometrial ciliated cells: 690.8;Ependymal cells: 3138.6;Epididymal efferent duct ciliated cells: 595.6;Fallopian tube ciliated cells: 904.2;Respiratory ciliated cells: 1781.6" "Cell type enriched" "Detected in all" 12 "ependymal cell: 3176.0" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 13.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bone cancer: 1.9;skin cancer: 1.9" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA020639, HPA052641" Enhanced Supported "Cytosol,Flagellar centriole,End piece" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 69: Skin cancer - ECM organization" "Cluster 34: Ciliated cells - Cilia assembly & function" 1 "Flagellar centriole, End piece" Cytosol "HPA020639: , HPA052641: " "unprognostic (3.34e-1)" "validated prognostic unfavorable (6.80e-4)" "validated prognostic unfavorable (4.11e-4)" "unprognostic (8.68e-3)" "unprognostic (1.01e-1)" "unprognostic (5.95e-3)" "unprognostic (6.94e-2)" "unprognostic (1.75e-1)" "unprognostic (1.35e-2)" "unprognostic (5.06e-3)" "potential prognostic unfavorable (6.75e-4)" "unprognostic (1.08e-1)" "unprognostic (1.81e-1)" "unprognostic (8.77e-2)" "unprognostic (9.47e-3)" "unprognostic (5.81e-2)" DNAI1 "CILD1, DIC1, PCD" ENSG00000122735 "Dynein axonemal intermediate chain 1" Q9UI46 9 34457414-34520988 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Motor protein" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "choroid plexus: 65.4;fallopian tube: 31.9;testis: 31.3" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 296.0;Endometrial ciliated cells: 278.0;Ependymal cells: 572.4;Epididymal efferent duct ciliated cells: 251.0;Fallopian tube ciliated cells: 296.2;Gonadotrophs: 145.2;Lactotrophs: 95.2;Late primary spermatocytes: 155.1;Respiratory ciliated cells: 495.3;Somatotrophs: 127.3;Thyrotrophs: 128.5" "Group enriched" "Detected in many" 9 "choroid plexus epithelial cell: 228.9;ependymal cell: 610.4" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 9.5" "Region enhanced" "Detected in all" "choroid plexus: 59.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "breast cancer: 1.2" "Adrenal gland - Adrenal medulla cells, Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Pancreas - Beta cells, Pituitary gland - Somatotropes, Stomach - Gastric enteroendocrine cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA021649, HPA021843" Enhanced Supported "Vesicles,Primary cilium,Mid piece,Principal piece,End piece" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 27: Breast cancer - Unknown function" "Cluster 34: Ciliated cells - Cilia assembly & function" 1 "Primary cilium, Mid piece, End piece" "Vesicles, Principal piece" "HPA021649: , HPA021843: " "unprognostic (4.14e-2)" "unprognostic (2.53e-1)" "unprognostic (1.91e-1)" "unprognostic (3.41e-3)" "unprognostic (7.14e-2)" "unprognostic (7.46e-2)" "unprognostic (1.69e-1)" "potential prognostic favorable (1.15e-4)" "unprognostic (4.46e-1)" "unprognostic (4.81e-2)" DNAI2 "CILD9, DIC2" ENSG00000171595 "Dynein axonemal intermediate chain 2" Q9GZS0 17 74274234-74314884 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Motor protein" "Ciliopathy, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "fallopian tube: 28.6;testis: 18.2" "Group enriched" "Detected in some" 4 "Endometrial ciliated cells: 169.2;Ependymal cells: 212.4;Epididymal efferent duct ciliated cells: 187.2;Fallopian tube ciliated cells: 253.1;Late primary spermatocytes: 124.2;Respiratory ciliated cells: 480.2" "Cell type enriched" "Detected in some" 5 "ependymal cell: 216.3" "Cancer enhanced" "Detected in some" "Lung Adenocarcinoma (TCGA): 1.2;Uterine Corpus Endometrial Carcinoma (TCGA): 1.8" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 7 "NK-cell: 3.8" "Lineage enriched" "Detected in single" 7 "NK-cells: 3.8" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Pituitary gland - Somatotropes, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB006245, HPA027105, HPA050565" Enhanced Approved "Calyx,Connecting piece,Mid piece" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" 2 "Connecting piece, Mid piece" Calyx "CAB006245: , HPA027105: , HPA050565: " "unprognostic (4.03e-2)" "unprognostic (1.23e-1)" DNAI3 "DIC3, FLJ30067, NYD-SP29, WDR63" ENSG00000162643 "Dynein axonemal intermediate chain 3" Q8IWG1 1 84999147-85133138 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adrenal gland: 20.6;choroid plexus: 40.0;fallopian tube: 13.6;testis: 17.6" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 179.5;Choroid plexus epithelial cells: 149.2;Endometrial ciliated cells: 212.6;Ependymal cells: 450.8;Epicardial cells: 138.7;Epididymal efferent duct ciliated cells: 219.1;Fallopian tube ciliated cells: 281.9;Gonadotrophs: 103.1;Late primary spermatocytes: 148.8;Melanocytes: 363.6;Respiratory ciliated cells: 285.8" "Group enriched" "Detected in many" 7 "choroid plexus epithelial cell: 143.1;ependymal cell: 501.6" "Group enriched" "Detected in some" 4 "Skin Cutaneous Melanoma (TCGA): 7.8;Uterine Corpus Endometrial Carcinoma (TCGA): 6.8" "Region enhanced" "Detected in all" "choroid plexus: 49.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 3.3" "Lung - Respiratory ciliated cells, Skin - Melanocytes, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA038526 Enhanced Approved "Perinuclear theca,Calyx,Connecting piece,Mid piece" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 50: Lymphoma - Unknown function" "Cluster 34: Ciliated cells - Cilia assembly & function" "Connecting piece" "Perinuclear theca, Calyx, Mid piece" "HPA038526: " "unprognostic (1.25e-2)" "unprognostic (1.66e-2)" "potential prognostic favorable (1.80e-4)" "unprognostic (2.67e-1)" "unprognostic (1.27e-1)" "unprognostic (1.26e-2)" "unprognostic (1.08e-1)" "unprognostic (1.20e-1)" "unprognostic (2.69e-2)" "unprognostic (2.45e-2)" DNAI4 "DIC4, FLJ23129, WDR78" ENSG00000152763 "Dynein axonemal intermediate chain 4" Q5VTH9 1 66812885-66924856 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 19.4;fallopian tube: 26.1;testis: 32.9" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 541.2;Endometrial ciliated cells: 267.4;Ependymal cells: 819.2;Epididymal efferent duct ciliated cells: 375.6;Fallopian tube ciliated cells: 470.1;Late primary spermatocytes: 302.8;Respiratory ciliated cells: 665.5" "Group enriched" "Detected in all" 8 "choroid plexus epithelial cell: 433.6;ependymal cell: 884.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "NK-cell: 3.8" "Lineage enriched" "Detected in single" 4 "NK-cells: 3.8" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA054315 Approved "Flagellar centriole,Mid piece,Principal piece" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" "Flagellar centriole" "Mid piece, Principal piece" "HPA054315: " "unprognostic (2.25e-1)" "unprognostic (3.50e-1)" "unprognostic (7.30e-3)" "potential prognostic favorable (8.70e-4)" "unprognostic (2.14e-1)" "unprognostic (8.94e-2)" "unprognostic (1.09e-3)" "potential prognostic favorable (7.55e-9)" "unprognostic (2.01e-3)" "unprognostic (2.18e-2)" "unprognostic (1.59e-1)" "unprognostic (1.05e-1)" "unprognostic (1.25e-2)" "unprognostic (1.59e-1)" "unprognostic (2.39e-1)" "unprognostic (2.91e-3)" "unprognostic (1.01e-2)" "unprognostic (9.14e-2)" "unprognostic (4.17e-2)" "unprognostic (1.23e-1)" "unprognostic (1.16e-1)" "unprognostic (8.31e-2)" "unprognostic (1.06e-1)" "unprognostic (8.30e-2)" "unprognostic (3.19e-2)" "unprognostic (1.37e-1)" DNAI7 "CASC1, CFAP94, FLJ10921, LAS1, PPP1R54" ENSG00000118307 "Dynein axonemal intermediate chain 7" Q6TDU7 12 25108289-25195162 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 13.5;fallopian tube: 13.2;testis: 21.4" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 355.5;Early spermatids: 373.3;Endometrial ciliated cells: 198.2;Ependymal cells: 589.2;Epididymal efferent duct ciliated cells: 201.5;Fallopian tube ciliated cells: 348.6;Late primary spermatocytes: 315.9;Respiratory ciliated cells: 503.6" "Group enriched" "Detected in all" 10 "choroid plexus epithelial cell: 317.6;ependymal cell: 660.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Bile duct cancer: 4.2" "Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary gland ductal cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA039662, HPA040141" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 34: Ciliated cells - Cilia assembly & function" 1 Cytosol Vesicles "HPA039662: , HPA040141: " "unprognostic (3.13e-2)" "potential prognostic favorable (7.89e-4)" "unprognostic (5.00e-2)" "unprognostic (2.45e-1)" "unprognostic (1.25e-2)" "potential prognostic favorable (4.15e-4)" "unprognostic (4.75e-2)" "potential prognostic favorable (9.51e-4)" "unprognostic (3.76e-2)" "unprognostic (2.82e-2)" "unprognostic (9.02e-2)" "unprognostic (1.76e-1)" "potential prognostic favorable (1.76e-4)" "unprognostic (1.02e-2)" "unprognostic (2.83e-1)" "unprognostic (2.48e-1)" "unprognostic (1.46e-1)" "unprognostic (5.26e-2)" "unprognostic (7.13e-2)" DNAJA1 "dj-2, hdj-2, HSJ2, HSPF4, NEDD7" ENSG00000086061 "DnaJ heat shock protein family (Hsp40) member A1" P31689 9 33025273-33039907 "Essential proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001306, CAB033665" Approved Supported Microtubules,Cytosol NA Yes 93000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 21: Non-specific - Metabolism" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 20: Non-specific - Transcription regulation" 112 Cytosol Microtubules "CAB033665: , HPA001306: " "unprognostic (1.18e-1)" "unprognostic (1.74e-2)" "unprognostic (1.70e-2)" "unprognostic (9.15e-2)" "unprognostic (2.03e-1)" "unprognostic (7.27e-2)" "unprognostic (2.68e-1)" "unprognostic (2.24e-1)" "unprognostic (1.13e-1)" "unprognostic (1.24e-1)" "potential prognostic favorable (1.40e-7)" "unprognostic (1.96e-2)" "unprognostic (7.11e-2)" "unprognostic (1.73e-2)" "unprognostic (3.80e-2)" "unprognostic (2.70e-2)" "unprognostic (1.14e-2)" "unprognostic (1.96e-1)" "unprognostic (6.96e-2)" "unprognostic (7.50e-3)" "unprognostic (4.31e-1)" "unprognostic (2.91e-2)" "unprognostic (1.59e-3)" "unprognostic (6.39e-2)" "unprognostic (2.76e-1)" "unprognostic (1.07e-1)" "unprognostic (3.99e-2)" "unprognostic (3.84e-1)" "unprognostic (2.45e-1)" "unprognostic (3.30e-1)" "unprognostic (2.46e-1)" DNAJA2 "CPR3, DNAJ, DNJ3, HIRIP4" ENSG00000069345 "DnaJ heat shock protein family (Hsp40) member A2" O60884 16 46955362-46973674 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 312.2;Oocytes: 303.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049789, HPA060538" Approved Approved Nucleoli,Cytosol NA NA 110000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 31: Non-specific - Transcription" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 118 "Nucleoli, Cytosol" "HPA049789: , HPA060538: " "unprognostic (2.69e-1)" "unprognostic (4.19e-3)" "unprognostic (1.73e-1)" "unprognostic (4.42e-2)" "unprognostic (1.15e-1)" "unprognostic (2.57e-1)" "unprognostic (1.94e-1)" "unprognostic (5.12e-2)" "unprognostic (1.36e-3)" "unprognostic (4.70e-2)" "potential prognostic favorable (4.42e-5)" "unprognostic (1.18e-3)" "unprognostic (4.53e-2)" "unprognostic (6.46e-2)" "unprognostic (3.22e-2)" "unprognostic (7.63e-2)" "unprognostic (5.60e-1)" "unprognostic (1.52e-1)" "unprognostic (1.88e-1)" "unprognostic (1.62e-1)" "unprognostic (3.99e-2)" "unprognostic (1.26e-1)" "unprognostic (3.93e-1)" "unprognostic (2.18e-1)" "unprognostic (1.15e-1)" "unprognostic (2.32e-1)" "unprognostic (4.03e-2)" "unprognostic (4.57e-2)" "unprognostic (1.88e-1)" "unprognostic (3.15e-2)" "unprognostic (1.65e-3)" DNAJA3 "hTid-1, TID1" ENSG00000103423 "DnaJ heat shock protein family (Hsp40) member A3" Q96EY1 16 4425805-4456775 "Essential proteins, Predicted intracellular proteins" Apoptosis Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 26.5;Brain inhibitory neurons: 26.4;Distal convoluted tubule cells: 27.9;Early spermatids: 36.8;Late primary spermatocytes: 43.1;Late spermatids: 32.8;Loop of henle epithelial cells: 24.5;Oligodendrocytes: 22.3;Other brain neurons: 27.9;Papillary tip epithelial cells: 24.4;Renal collecting duct intercalated cells: 29.8;Renal collecting duct principal cells: 24.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016095, HPA040875, HPA044229" Approved Supported Vesicles,Mitochondria NA NA 33000 "Cluster 24: Non-specific - Transcription" "Cluster 24: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 98: Neurons - Neurotransmission & signaling" 47 Mitochondria Vesicles "CAB016095: , HPA040875: , HPA044229: " "unprognostic (2.10e-2)" "unprognostic (7.11e-3)" "unprognostic (1.42e-2)" "unprognostic (9.34e-3)" "unprognostic (3.60e-2)" "unprognostic (1.49e-1)" "unprognostic (6.01e-2)" "unprognostic (7.60e-3)" "unprognostic (2.05e-1)" "unprognostic (2.17e-2)" "potential prognostic favorable (3.38e-5)" "unprognostic (1.26e-1)" "unprognostic (1.22e-1)" "unprognostic (9.00e-3)" "unprognostic (9.61e-3)" "unprognostic (2.57e-2)" "unprognostic (6.76e-2)" "unprognostic (3.37e-1)" "unprognostic (1.55e-1)" "unprognostic (2.76e-2)" "unprognostic (2.92e-1)" "unprognostic (4.28e-3)" "unprognostic (8.24e-3)" "unprognostic (2.35e-3)" "potential prognostic favorable (7.23e-4)" "unprognostic (3.69e-1)" "unprognostic (1.13e-1)" "unprognostic (3.38e-1)" "unprognostic (1.75e-1)" "unprognostic (2.61e-1)" "unprognostic (1.81e-1)" DNAJA4 PRO1472 ENSG00000140403 "DnaJ heat shock protein family (Hsp40) member A4" Q8WW22 15 78264086-78282196 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 135.1" "Cell type enhanced" "Detected in many" "Breast lactating cells: 259.9;Early spermatids: 842.3;Epididymal efferent duct absorptive cells: 494.8;Epididymal efferent duct ciliated cells: 415.5;Late spermatids: 2211.9;Respiratory ciliated cells: 267.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Skin - Keratinocyte (other), Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004646, HPA041790" Uncertain Approved "Nuclear membrane,Plasma membrane,Primary cilium,Centriolar satellite,Basal body,Cytosol" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 52: Non-specific - Cellular respiration" "Cluster 1: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 16 "Plasma membrane, Cytosol" "Nuclear membrane, Primary cilium, Centriolar satellite, Basal body" "CAB004646: , HPA041790: " "potential prognostic favorable (6.30e-4)" "unprognostic (5.98e-2)" "unprognostic (1.71e-1)" "unprognostic (1.80e-1)" "unprognostic (1.84e-1)" "unprognostic (7.85e-2)" "unprognostic (1.24e-3)" "unprognostic (5.29e-3)" "unprognostic (1.16e-1)" "unprognostic (1.66e-1)" "potential prognostic favorable (8.85e-6)" "unprognostic (7.79e-3)" "unprognostic (2.12e-3)" "unprognostic (2.11e-2)" "unprognostic (1.55e-3)" "unprognostic (5.07e-2)" "unprognostic (5.88e-2)" "unprognostic (2.26e-1)" "unprognostic (1.25e-1)" "unprognostic (1.17e-1)" "potential prognostic favorable (8.16e-4)" "unprognostic (2.80e-2)" "unprognostic (3.09e-3)" "unprognostic (6.23e-2)" "unprognostic (1.05e-1)" "unprognostic (1.72e-1)" "unprognostic (3.31e-2)" "unprognostic (8.78e-2)" "unprognostic (2.34e-1)" "unprognostic (5.87e-2)" "unprognostic (1.93e-1)" DNAJB1 "Hsp40, HSPF1, RSPH16B, Sis1" ENSG00000132002 "DnaJ heat shock protein family (Hsp40) member B1" P25685 19 14514769-14560391 "Cancer-related genes, Predicted intracellular proteins" "Stress response" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epididymal efferent duct absorptive cells: 1640.6;Esophageal apical cells: 2850.7;Pancreatic duct cells: 2411.4" "Cell type enhanced" "Detected in all" "endothelial cell: 153.4;leukocyte: 169.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017450, HPA063247" Enhanced Supported Nucleoplasm,Cytosol NA Yes 32000 "Cluster 31: T-cells - T-cell receptor" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 55: Non-specific - Transcription" "Cluster 23: Non-specific - Transcription" "Cluster 75: Non-specific - Chaperones and protein folding" 106 Nucleoplasm Cytosol "CAB017450: , HPA063247: " "unprognostic (1.96e-1)" "unprognostic (5.13e-3)" "unprognostic (5.57e-2)" "unprognostic (2.02e-1)" "unprognostic (2.75e-1)" "unprognostic (1.12e-1)" "unprognostic (1.94e-1)" "unprognostic (1.43e-1)" "unprognostic (1.85e-1)" "unprognostic (9.50e-2)" "potential prognostic favorable (2.95e-5)" "unprognostic (1.06e-1)" "unprognostic (1.16e-1)" "unprognostic (1.56e-1)" "unprognostic (3.43e-2)" "unprognostic (1.04e-2)" "unprognostic (4.03e-2)" "unprognostic (2.70e-1)" "unprognostic (2.06e-1)" "unprognostic (5.16e-2)" "unprognostic (2.29e-2)" "unprognostic (1.25e-2)" "unprognostic (1.29e-3)" "unprognostic (2.17e-1)" "unprognostic (3.26e-1)" "unprognostic (9.69e-3)" "unprognostic (5.84e-2)" "unprognostic (5.49e-2)" "unprognostic (3.15e-2)" "unprognostic (6.47e-3)" "unprognostic (1.67e-1)" DNAJB11 "EDJ, ERdj3, HEDJ" ENSG00000090520 "DnaJ heat shock protein family (Hsp40) member B11" Q9UBS4 3 186567403-186585800 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Chaperone "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 191.2;Plasma cells: 98.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010814, HPA017051" Supported Supported "Endoplasmic reticulum" "Intracellular and membrane" Other NA NA 270000 "Cluster 29: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 65: Non-specific - Cell growth & division" 85 "Endoplasmic reticulum" "HPA010814: , HPA017051: " "unprognostic (8.00e-2)" "unprognostic (5.52e-2)" "unprognostic (9.25e-2)" "unprognostic (3.79e-2)" "unprognostic (1.44e-1)" "unprognostic (8.06e-3)" "unprognostic (1.82e-1)" "unprognostic (8.66e-2)" "potential prognostic unfavorable (7.88e-4)" "unprognostic (1.27e-1)" "unprognostic (6.23e-2)" "unprognostic (2.24e-3)" "unprognostic (3.58e-2)" "unprognostic (9.67e-3)" "unprognostic (3.42e-3)" "unprognostic (2.12e-2)" "unprognostic (1.23e-2)" "unprognostic (1.69e-2)" "unprognostic (3.16e-2)" "unprognostic (2.18e-2)" "unprognostic (1.79e-1)" "unprognostic (6.09e-3)" "unprognostic (6.65e-3)" "unprognostic (7.96e-2)" "unprognostic (2.01e-1)" "unprognostic (1.66e-1)" "unprognostic (1.94e-1)" "unprognostic (4.94e-1)" "unprognostic (6.46e-2)" "unprognostic (6.01e-2)" "unprognostic (1.30e-1)" DNAJB12 "DJ10, FLJ20027" ENSG00000148719 "DnaJ heat shock protein family (Hsp40) member B12" Q9NXW2 10 72332830-72355149 "Predicted membrane proteins, Transporters" "Host-virus interaction" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 347.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010642, HPA072702" Approved Supported "Nuclear membrane,Endoplasmic reticulum" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 70: Non-specific - Protein processing" "Cluster 25: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 31 "Nuclear membrane, Endoplasmic reticulum" "HPA010642: , HPA072702: " "unprognostic (5.47e-2)" "unprognostic (4.06e-2)" "unprognostic (7.79e-2)" "unprognostic (3.96e-2)" "unprognostic (2.95e-1)" "unprognostic (5.77e-2)" "unprognostic (9.84e-2)" "potential prognostic favorable (1.48e-5)" "unprognostic (2.65e-3)" "unprognostic (1.59e-1)" "unprognostic (5.28e-3)" "unprognostic (1.91e-1)" "unprognostic (5.09e-3)" "potential prognostic unfavorable (6.82e-4)" "unprognostic (2.03e-1)" "unprognostic (8.39e-2)" "unprognostic (2.93e-1)" "unprognostic (1.33e-3)" "unprognostic (2.37e-2)" "unprognostic (6.81e-2)" "unprognostic (7.64e-2)" "unprognostic (3.35e-1)" "unprognostic (1.53e-2)" "unprognostic (1.36e-1)" "unprognostic (3.79e-2)" "unprognostic (3.83e-2)" "unprognostic (5.52e-3)" "unprognostic (1.10e-1)" "unprognostic (2.49e-1)" "unprognostic (4.80e-2)" "unprognostic (1.45e-1)" DNAJB13 "RSPH16A, TSARG6" ENSG00000187726 "DnaJ heat shock protein family (Hsp40) member B13" P59910 11 73951026-73970366 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" Chaperone "Ciliopathy, Disease variant, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "choroid plexus: 25.4;fallopian tube: 50.1;testis: 18.0" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 52.8;Early spermatids: 76.8;Endometrial ciliated cells: 170.5;Ependymal cells: 110.1;Epididymal efferent duct ciliated cells: 141.0;Fallopian tube ciliated cells: 273.2;Late primary spermatocytes: 91.4;Late spermatids: 80.8;Oocytes: 41.4;Respiratory ciliated cells: 137.4" "Group enriched" "Detected in many" 23 "choroid plexus epithelial cell: 40.5;ependymal cell: 113.2" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 21.4;Uterine Corpus Endometrial Carcinoma (TCGA): 25.9" "Region enhanced" "Detected in all" "choroid plexus: 23.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA052465, HPA061330" Enhanced Uncertain "Nucleoli,Nucleoli rim,Mitotic chromosome,Vesicles,Plasma membrane,Primary cilium,Primary cilium tip,Mid piece,Principal piece,End piece" Yes NA "Cluster 41: Basophils - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 107: Ciliated cells - Cilia assembly & function" 10 "Plasma membrane, Mid piece, Principal piece, End piece" "Nucleoli, Nucleoli rim, Mitotic chromosome, Vesicles, Primary cilium, Primary cilium tip" "HPA052465: , HPA061330: " "unprognostic (1.53e-2)" "unprognostic (4.15e-1)" "unprognostic (4.39e-2)" "unprognostic (1.99e-2)" "unprognostic (2.97e-1)" "unprognostic (4.64e-3)" "unprognostic (1.54e-1)" "unprognostic (2.75e-1)" "unprognostic (1.10e-2)" "unprognostic (1.32e-1)" "unprognostic (7.84e-2)" "unprognostic (2.00e-1)" "unprognostic (5.12e-2)" "unprognostic (5.37e-2)" "unprognostic (6.36e-2)" "unprognostic (1.72e-1)" "unprognostic (7.12e-2)" DNAJB14 FLJ14281 ENSG00000164031 "DnaJ heat shock protein family (Hsp40) member B14" Q8TBM8 4 99896248-99946618 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036016, HPA057968" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 42: Retina - Visual perception" "Cluster 14: Neurons - Synaptic function" "Cluster 38: Non-specific - Transcription" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 4 "Endoplasmic reticulum" "HPA036016: , HPA057968: " "unprognostic (6.95e-3)" "unprognostic (2.73e-2)" "unprognostic (2.65e-1)" "unprognostic (1.30e-2)" "unprognostic (7.58e-2)" "unprognostic (8.97e-3)" "unprognostic (2.60e-1)" "unprognostic (3.31e-1)" "unprognostic (2.65e-2)" "unprognostic (2.88e-2)" "validated prognostic favorable (2.47e-9)" "validated prognostic favorable (4.25e-6)" "unprognostic (1.32e-1)" "unprognostic (1.32e-2)" "unprognostic (7.30e-2)" "unprognostic (2.29e-2)" "unprognostic (1.18e-1)" "unprognostic (1.51e-1)" "unprognostic (3.53e-1)" "unprognostic (7.15e-3)" "unprognostic (1.38e-3)" "unprognostic (7.59e-2)" "unprognostic (9.89e-3)" "unprognostic (3.24e-2)" "unprognostic (6.73e-2)" "unprognostic (5.54e-2)" "unprognostic (1.38e-1)" "unprognostic (8.66e-2)" "unprognostic (1.52e-1)" "unprognostic (6.53e-2)" "unprognostic (6.07e-3)" DNAJB2 "CMT2T, HSJ1, HSPF3" ENSG00000135924 "DnaJ heat shock protein family (Hsp40) member B2" P25686 2 219279342-219286898 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Chaperone "Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 284.8" "Cell type enhanced" "Detected in many" "Breast lactating cells: 252.2;Epididymal principal cells: 142.9;Esophageal apical cells: 157.5;Oligodendrocytes: 160.3" "Cell type enhanced" "Detected in all" "oligodendrocyte: 189.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036268 Approved Enhanced "Nuclear membrane" NA NA 5000 "Cluster 22: Eosinophils - Transcription" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 62: Non-specific - Plasma proteins" "Cluster 97: Non-specific - Cellular respiration" 15 "Nuclear membrane" "HPA036268: " "unprognostic (1.77e-2)" "unprognostic (1.04e-2)" "unprognostic (3.43e-1)" "unprognostic (6.15e-2)" "unprognostic (7.44e-2)" "unprognostic (2.88e-3)" "unprognostic (8.81e-2)" "unprognostic (5.82e-2)" "unprognostic (1.78e-1)" "unprognostic (3.64e-1)" "potential prognostic favorable (4.25e-4)" "unprognostic (3.08e-2)" "unprognostic (1.80e-1)" "potential prognostic unfavorable (2.35e-5)" "unprognostic (5.81e-2)" "unprognostic (2.11e-1)" "unprognostic (1.76e-1)" "unprognostic (1.85e-2)" "unprognostic (5.06e-2)" "unprognostic (4.32e-2)" "unprognostic (3.12e-1)" "unprognostic (8.12e-2)" "potential prognostic unfavorable (5.71e-4)" "unprognostic (2.79e-1)" "unprognostic (3.24e-2)" "unprognostic (1.84e-1)" "unprognostic (1.11e-1)" "unprognostic (1.40e-1)" "unprognostic (2.61e-2)" "unprognostic (6.15e-2)" "unprognostic (3.54e-2)" DNAJB4 HLJ1 ENSG00000162616 "DnaJ heat shock protein family (Hsp40) member B4" Q9UDY4 1 77979175-78017964 "Plasma proteins, Predicted intracellular proteins" "Stress response" Chaperone "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 21.9;Early spermatids: 113.6;Late primary spermatocytes: 32.7;Late spermatids: 58.5;Pancreatic duct cells: 14.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004995, HPA028383, HPA028385" Approved Enhanced "Nucleoplasm,Plasma membrane,Cytosol" NA NA 8100 "Cluster 30: Non-specific - DNA binding" "Cluster 35: Non-specific - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 60 Nucleoplasm "Plasma membrane, Cytosol" "CAB004995: , HPA028383: , HPA028385: " "unprognostic (7.98e-2)" "unprognostic (7.32e-2)" "unprognostic (3.09e-1)" "unprognostic (8.77e-3)" "unprognostic (2.94e-1)" "unprognostic (1.40e-1)" "unprognostic (5.92e-2)" "unprognostic (3.78e-1)" "unprognostic (1.64e-3)" "unprognostic (3.53e-1)" "validated prognostic favorable (1.94e-6)" "validated prognostic favorable (5.20e-4)" "unprognostic (4.00e-2)" "unprognostic (1.81e-3)" "unprognostic (7.94e-2)" "potential prognostic unfavorable (2.47e-4)" "unprognostic (8.56e-2)" "unprognostic (3.67e-1)" "unprognostic (5.64e-2)" "unprognostic (3.49e-2)" "unprognostic (1.11e-3)" "unprognostic (2.62e-1)" "unprognostic (1.59e-2)" "unprognostic (2.66e-1)" "unprognostic (3.54e-1)" "unprognostic (5.74e-2)" "unprognostic (1.33e-1)" "unprognostic (2.57e-3)" "unprognostic (4.72e-1)" "unprognostic (1.29e-3)" "unprognostic (3.62e-2)" DNAJB5 Hsc40 ENSG00000137094 "DnaJ heat shock protein family (Hsp40) member B5" O75953 9 34989641-34998900 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 154.1;tongue: 203.7" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 28.4;Epicardial cells: 54.6;Epididymal principal cells: 17.8;Lactotrophs: 18.9;Myonuclei: 17.5;Schwann cells: 16.5;Smooth muscle cells: 37.7;Vascular smooth muscle cells: 21.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "myeloid DC: 5.5;neutrophil: 5.2" "Group enriched" "Detected in many" 5 "dendritic cells: 5.5;granulocytes: 5.2" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Colon - Smooth muscle cells, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Spleen - Fibroblasts_1, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023818, HPA050794" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - DNA binding" "Cluster 72: Neuronal - Signal transduction" "Cluster 62: Smooth muscle cells - Muscle contraction" 23 Nucleoplasm Cytosol "HPA023818: , HPA050794: " "unprognostic (2.65e-1)" "unprognostic (5.93e-3)" "unprognostic (9.44e-2)" "unprognostic (6.99e-2)" "unprognostic (2.31e-2)" "unprognostic (1.47e-2)" "unprognostic (8.05e-2)" "unprognostic (1.95e-3)" "unprognostic (1.15e-2)" "unprognostic (1.86e-2)" "potential prognostic favorable (5.65e-4)" "unprognostic (1.02e-1)" "unprognostic (1.35e-2)" "unprognostic (2.74e-1)" "unprognostic (4.59e-2)" "unprognostic (9.55e-2)" "unprognostic (7.77e-2)" "unprognostic (6.23e-2)" "unprognostic (1.10e-1)" "unprognostic (5.48e-2)" "unprognostic (3.87e-1)" "unprognostic (7.62e-3)" "unprognostic (4.00e-2)" "unprognostic (6.15e-2)" "unprognostic (3.56e-2)" "unprognostic (5.09e-2)" "unprognostic (2.69e-1)" "unprognostic (2.73e-3)" "unprognostic (1.41e-1)" "unprognostic (5.54e-2)" "unprognostic (2.04e-2)" DNAJB6 "LGMD1D, MRJ" ENSG00000105993 "DnaJ heat shock protein family (Hsp40) member B6" O75190 7 157335381-157417439 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Chaperone "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Breast lactating cells: 1094.4;Esophageal apical cells: 930.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004670, HPA024258, HPA058593" Supported Supported Nucleoplasm,Cytosol NA NA 8600 "Cluster 42: Non-specific - Vesicular transport" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 39: Non-specific - Transcription" "Cluster 75: Non-specific - Chaperones and protein folding" 82 Nucleoplasm Cytosol "CAB004670: , HPA024258: , HPA058593: " "unprognostic (6.78e-2)" "unprognostic (1.02e-1)" "unprognostic (1.89e-1)" "unprognostic (8.66e-2)" "unprognostic (2.83e-2)" "unprognostic (2.42e-2)" "unprognostic (2.74e-3)" "unprognostic (1.31e-1)" "unprognostic (2.45e-1)" "unprognostic (9.37e-2)" "potential prognostic favorable (9.88e-5)" "unprognostic (3.40e-2)" "unprognostic (6.92e-2)" "potential prognostic unfavorable (1.92e-4)" "unprognostic (1.03e-3)" "unprognostic (1.45e-2)" "unprognostic (3.21e-2)" "unprognostic (3.13e-1)" "unprognostic (1.11e-2)" "unprognostic (3.05e-3)" "unprognostic (2.17e-2)" "unprognostic (1.14e-2)" "unprognostic (5.50e-2)" "unprognostic (8.15e-2)" "unprognostic (1.11e-1)" "unprognostic (1.51e-1)" "unprognostic (1.81e-1)" "unprognostic (1.93e-1)" "unprognostic (1.64e-1)" "unprognostic (7.39e-2)" "unprognostic (2.14e-1)" DNAJB7 HSC3 ENSG00000172404 "DnaJ heat shock protein family (Hsp40) member B7" Q7Z6W7 22 40859549-40862113 "Predicted intracellular proteins" Chaperone "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 13 "testis: 10.0" "Cell type enriched" "Detected in some" 6 "Early spermatids: 726.2" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" HPA000534 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 48: Non-specific - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 1 Nucleoplasm "Golgi apparatus, Cytosol" "HPA000534: " "unprognostic (5.53e-2)" "unprognostic (1.12e-1)" DNAJB8 "CT156, MGC33884" ENSG00000179407 "DnaJ heat shock protein family (Hsp40) member B8" Q8NHS0 3 128462437-128466968 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 580 "testis: 57.9" "Cell type enriched" "Detected in some" 5 "Late spermatids: 6975.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 15 DNAJB9 MDG1 ENSG00000128590 "DnaJ heat shock protein family (Hsp40) member B9" Q9UBS3 7 108569867-108574850 "Predicted intracellular proteins" "Unfolded protein response" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 391.2;Epididymal efferent duct absorptive cells: 317.7;Epididymal principal cells: 332.4;Late primary spermatocytes: 292.0;Late spermatids: 289.7;Plasma cells: 397.8;Syncytiotrophoblasts: 828.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040967, HPA041553" Supported Approved "Endoplasmic reticulum,Cytosol" "Intracellular and membrane" Other NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 22: Epididymis - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 103: Non-specific - Basic cellular processes" 65 "Endoplasmic reticulum, Cytosol" "HPA040967: , HPA041553: " "unprognostic (5.04e-3)" "unprognostic (3.58e-2)" "unprognostic (4.58e-1)" "unprognostic (2.52e-2)" "unprognostic (2.36e-1)" "unprognostic (7.48e-2)" "unprognostic (2.98e-3)" "unprognostic (8.51e-3)" "unprognostic (4.95e-1)" "unprognostic (6.53e-2)" "potential prognostic favorable (1.44e-10)" "unprognostic (3.01e-2)" "unprognostic (3.13e-2)" "unprognostic (1.86e-1)" "unprognostic (1.40e-2)" "unprognostic (6.08e-3)" "unprognostic (5.41e-2)" "unprognostic (8.75e-3)" "unprognostic (1.31e-1)" "unprognostic (1.84e-1)" "unprognostic (8.69e-2)" "unprognostic (1.95e-1)" "potential prognostic unfavorable (2.74e-4)" "unprognostic (1.02e-1)" "unprognostic (2.59e-2)" "unprognostic (5.50e-2)" "unprognostic (4.90e-2)" "unprognostic (2.54e-1)" "unprognostic (2.43e-1)" "unprognostic (4.52e-2)" "unprognostic (1.81e-2)" DNAJC1 "DNAJL1, ERdj1, MTJ1" ENSG00000136770 "DnaJ heat shock protein family (Hsp40) member C1" Q96KC8 10 21756548-22003769 "Predicted membrane proteins, Transcription factors" "Chaperone, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 775.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Myeloma: 135.5" "Minor Salivary Gland - Minor salivary glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013432 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 70: Non-specific - Protein processing" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 8: Non-specific - Secretory pathway" 33 "Endoplasmic reticulum" "HPA013432: " "unprognostic (1.11e-1)" "unprognostic (3.58e-1)" "unprognostic (2.85e-1)" "unprognostic (1.68e-1)" "unprognostic (5.32e-2)" "unprognostic (2.52e-2)" "unprognostic (5.36e-2)" "unprognostic (1.28e-1)" "unprognostic (1.49e-1)" "unprognostic (7.90e-2)" "potential prognostic favorable (1.15e-7)" "unprognostic (3.79e-3)" "unprognostic (2.93e-3)" "potential prognostic unfavorable (2.51e-5)" "unprognostic (1.17e-2)" "unprognostic (5.76e-3)" "unprognostic (2.74e-1)" "unprognostic (2.07e-1)" "unprognostic (2.20e-1)" "unprognostic (5.24e-2)" "unprognostic (2.33e-1)" "unprognostic (1.49e-1)" "unprognostic (1.35e-1)" "unprognostic (6.96e-2)" "unprognostic (1.46e-1)" "unprognostic (5.43e-2)" "unprognostic (1.62e-1)" "unprognostic (3.85e-2)" "unprognostic (4.17e-2)" "unprognostic (8.83e-2)" "unprognostic (8.96e-2)" DNAJC10 "ERdj5, PDIA19" ENSG00000077232 "DnaJ heat shock protein family (Hsp40) member C10" Q8IXB1 2 182716255-182794464 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 107.6" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 434.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Skin - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031111 Approved NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 22: Epididymis - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 21 "HPA031111: " "unprognostic (3.25e-1)" "unprognostic (1.87e-2)" "unprognostic (1.12e-1)" "unprognostic (1.11e-2)" "unprognostic (2.91e-2)" "unprognostic (2.19e-1)" "unprognostic (4.59e-1)" "unprognostic (3.11e-2)" "unprognostic (3.07e-1)" "unprognostic (1.31e-1)" "unprognostic (1.03e-3)" "unprognostic (1.76e-1)" "potential prognostic unfavorable (7.35e-4)" "unprognostic (3.78e-2)" "unprognostic (5.18e-2)" "unprognostic (1.87e-2)" "unprognostic (1.54e-1)" "unprognostic (1.40e-2)" "unprognostic (1.52e-1)" "unprognostic (2.54e-1)" "unprognostic (4.05e-2)" "unprognostic (1.41e-2)" "unprognostic (3.81e-1)" "unprognostic (9.09e-2)" "unprognostic (2.16e-1)" "unprognostic (1.63e-1)" "unprognostic (2.97e-2)" "unprognostic (2.16e-1)" "unprognostic (1.42e-1)" "potential prognostic unfavorable (4.91e-4)" "unprognostic (1.28e-1)" DNAJC11 FLJ10737 ENSG00000007923 "DnaJ heat shock protein family (Hsp40) member C11" Q9NVH1 1 6634168-6701924 "Essential proteins, Predicted intracellular proteins, Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 146.3;Loop of henle epithelial cells: 145.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023707, HPA028705" Uncertain Supported Mitochondria No No "Cluster 13: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cellular respiration" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 37: Non-specific - mRNA processing" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 44 Mitochondria "HPA023707: , HPA028705: " "unprognostic (1.06e-1)" "unprognostic (1.53e-2)" "unprognostic (2.11e-1)" "unprognostic (5.34e-3)" "unprognostic (3.74e-2)" "unprognostic (1.36e-1)" "unprognostic (2.28e-1)" "potential prognostic favorable (6.40e-4)" "unprognostic (8.10e-2)" "unprognostic (2.15e-1)" "potential prognostic favorable (4.16e-5)" "unprognostic (5.45e-3)" "potential prognostic favorable (2.57e-4)" "validated prognostic unfavorable (1.91e-4)" "validated prognostic unfavorable (8.37e-4)" "unprognostic (4.69e-2)" "unprognostic (1.32e-2)" "unprognostic (3.11e-1)" "unprognostic (1.14e-1)" "unprognostic (2.37e-1)" "unprognostic (4.32e-2)" "unprognostic (5.97e-2)" "unprognostic (1.66e-1)" "unprognostic (1.00e-1)" "unprognostic (1.84e-1)" "unprognostic (9.02e-2)" "unprognostic (1.96e-1)" "unprognostic (1.36e-1)" "unprognostic (1.26e-1)" "unprognostic (5.76e-2)" "unprognostic (1.39e-1)" DNAJC12 JDP1 ENSG00000108176 "DnaJ heat shock protein family (Hsp40) member C12" Q9UKB3 10 67796669-67838188 "Disease related genes, Predicted intracellular proteins" Chaperone "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 66.9;brain: 82.3;liver: 63.1" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 125.7;Breast lactating cells: 305.7;Goblet cells: 73.4;Gonadotrophs: 63.5;Hepatocytes: 94.7;Neuroendocrine cells: 160.5;Pancreatic acinar cells: 108.7;Pancreatic islet cells: 390.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 67.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "plasmacytoid DC: 7.7" "Lineage enriched" "Detected in single" 24 "dendritic cells: 7.7" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Breast - Breast glandular cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036289 Enhanced NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 76: Non-specific - Metabolism" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 2 "HPA036289: " "unprognostic (1.50e-1)" "unprognostic (2.52e-2)" "unprognostic (9.54e-2)" "unprognostic (2.40e-2)" "unprognostic (9.50e-2)" "unprognostic (1.43e-1)" "unprognostic (1.43e-1)" "unprognostic (2.66e-3)" "unprognostic (4.54e-3)" "potential prognostic unfavorable (3.34e-6)" "unprognostic (5.95e-3)" "unprognostic (1.19e-1)" "unprognostic (1.80e-2)" "unprognostic (1.16e-1)" "unprognostic (1.39e-1)" "unprognostic (4.48e-1)" "unprognostic (1.75e-1)" "unprognostic (6.00e-2)" "unprognostic (1.15e-1)" "unprognostic (2.21e-1)" "unprognostic (4.94e-2)" "unprognostic (1.13e-1)" "unprognostic (1.59e-2)" "unprognostic (3.39e-1)" "potential prognostic unfavorable (1.36e-4)" "unprognostic (3.95e-1)" "unprognostic (6.41e-3)" "unprognostic (8.64e-2)" "unprognostic (1.36e-2)" DNAJC13 "KIAA0678, RME8" ENSG00000138246 "DnaJ heat shock protein family (Hsp40) member C13" O75165 3 132417502-132539032 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Protein transport, Transport" Chaperone "Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophil progenitors: 438.0;Retinal horizontal cells: 218.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036923, HPA036924" Approved Supported Vesicles,Cytosol NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 75: Ovary - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 35 Vesicles Cytosol "HPA036923: , HPA036924: " "unprognostic (1.24e-2)" "unprognostic (8.05e-3)" "unprognostic (2.02e-1)" "unprognostic (1.12e-2)" "unprognostic (1.99e-1)" "unprognostic (7.83e-2)" "unprognostic (1.07e-1)" "unprognostic (1.32e-1)" "unprognostic (1.99e-2)" "potential prognostic unfavorable (3.44e-4)" "potential prognostic favorable (2.55e-5)" "unprognostic (1.05e-1)" "unprognostic (2.75e-1)" "unprognostic (3.08e-3)" "unprognostic (3.41e-2)" "unprognostic (1.42e-2)" "unprognostic (2.94e-2)" "unprognostic (1.60e-1)" "unprognostic (2.64e-1)" "unprognostic (2.70e-1)" "unprognostic (1.55e-2)" "unprognostic (3.60e-3)" "potential prognostic unfavorable (6.35e-4)" "unprognostic (2.05e-1)" "unprognostic (7.21e-2)" "unprognostic (6.94e-2)" "unprognostic (1.08e-1)" "unprognostic (1.74e-1)" "unprognostic (1.35e-1)" "unprognostic (6.50e-3)" "unprognostic (2.78e-3)" DNAJC14 "DNAJ, DRIP78, FLJ32792, HDJ3, LIP6" ENSG00000135392 "DnaJ heat shock protein family (Hsp40) member C14" Q6Y2X3 12 55820960-55830824 "Predicted membrane proteins" "Protein transport, Transport" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Adipocytes: 44.9;Cardiomyocytes: 22.0;Epicardial cells: 47.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Colon - Macrophages, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017653 Approved NA NA "Cluster 32: Basophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 38: Non-specific - Transcription" "Cluster 89: Adipocytes - Lipid metabolism" 4 "HPA017653: " "unprognostic (4.31e-2)" "unprognostic (1.26e-2)" "potential prognostic favorable (1.49e-4)" "unprognostic (6.23e-3)" "unprognostic (1.32e-1)" "unprognostic (1.91e-2)" "unprognostic (1.61e-1)" "unprognostic (1.67e-1)" "unprognostic (2.19e-1)" "unprognostic (7.97e-3)" "potential prognostic favorable (5.16e-4)" "unprognostic (9.12e-2)" "unprognostic (2.59e-1)" "unprognostic (1.21e-2)" "unprognostic (5.86e-3)" "unprognostic (4.08e-2)" "unprognostic (5.14e-3)" "unprognostic (8.44e-2)" "unprognostic (4.42e-2)" "unprognostic (9.24e-2)" "unprognostic (1.16e-2)" "unprognostic (3.50e-1)" "unprognostic (9.08e-2)" "unprognostic (1.00e-1)" "unprognostic (1.83e-1)" "unprognostic (1.20e-1)" "unprognostic (4.75e-2)" "unprognostic (5.62e-2)" "unprognostic (1.78e-1)" "unprognostic (1.10e-1)" "unprognostic (1.56e-2)" DNAJC15 "DNAJD1, MCJ" ENSG00000120675 "DnaJ heat shock protein family (Hsp40) member C15" Q9Y5T4 13 43023203-43114213 "Disease related genes, Predicted membrane proteins" "Protein transport, Translocation, Transport" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 437.9;Extravillous trophoblasts: 438.1;Gastric progenitor cells: 437.1;Late primary spermatocytes: 731.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 10 "unprognostic (2.29e-2)" "unprognostic (2.31e-1)" "unprognostic (1.13e-2)" "unprognostic (3.52e-2)" "unprognostic (5.91e-2)" "unprognostic (3.92e-1)" "unprognostic (9.66e-3)" "potential prognostic unfavorable (9.16e-4)" "potential prognostic unfavorable (6.63e-4)" "unprognostic (5.25e-2)" "unprognostic (1.08e-3)" "unprognostic (2.85e-3)" "unprognostic (5.60e-2)" "unprognostic (6.71e-2)" "unprognostic (1.37e-2)" "unprognostic (1.05e-1)" "unprognostic (8.40e-3)" "unprognostic (9.66e-2)" "unprognostic (5.65e-2)" "unprognostic (2.43e-1)" "unprognostic (2.18e-1)" "unprognostic (1.31e-2)" "unprognostic (2.40e-2)" "unprognostic (3.20e-1)" "unprognostic (2.95e-1)" "unprognostic (2.14e-1)" "unprognostic (1.91e-1)" "unprognostic (2.78e-2)" "unprognostic (4.07e-2)" "unprognostic (1.51e-1)" "unprognostic (2.42e-1)" DNAJC16 KIAA0962 ENSG00000116138 "DnaJ heat shock protein family (Hsp40) member C16" Q9Y2G8 1 15526813-15592379 "Predicted membrane proteins" Autophagy "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043643 Approved Approved Vesicles NA NA "Cluster 24: Non-specific - Transcription" "Cluster 76: Non-specific - Metabolism" "Cluster 31: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 41 Vesicles "HPA043643: " "unprognostic (6.65e-2)" "unprognostic (3.89e-2)" "unprognostic (2.86e-1)" "unprognostic (7.68e-2)" "unprognostic (3.87e-2)" "unprognostic (7.55e-2)" "unprognostic (1.08e-1)" "unprognostic (1.10e-1)" "unprognostic (2.06e-2)" "unprognostic (2.80e-3)" "validated prognostic favorable (3.31e-7)" "validated prognostic favorable (2.64e-4)" "unprognostic (2.66e-2)" "unprognostic (2.52e-3)" "unprognostic (1.28e-1)" "unprognostic (4.10e-1)" "unprognostic (2.56e-1)" "unprognostic (3.45e-2)" "unprognostic (1.15e-2)" "unprognostic (1.19e-2)" "unprognostic (2.17e-1)" "unprognostic (4.70e-2)" "unprognostic (2.06e-1)" "unprognostic (6.48e-2)" "unprognostic (1.50e-1)" "unprognostic (4.23e-1)" "unprognostic (4.70e-1)" "unprognostic (4.12e-2)" "unprognostic (1.57e-1)" "unprognostic (1.49e-1)" "unprognostic (1.97e-1)" DNAJC17 FLJ10634 ENSG00000104129 "DnaJ heat shock protein family (Hsp40) member C17" Q9NVM6 15 40765161-40807478 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chaperone, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040914, HPA041187" Approved Approved Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 75: Ovary - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 54 Nucleoplasm "HPA040914: , HPA041187: " "unprognostic (5.63e-2)" "unprognostic (2.25e-1)" "unprognostic (5.86e-2)" "unprognostic (2.60e-3)" "unprognostic (1.22e-2)" "unprognostic (1.54e-1)" "unprognostic (1.63e-1)" "unprognostic (1.42e-3)" "unprognostic (1.52e-2)" "unprognostic (1.61e-1)" "potential prognostic favorable (9.19e-6)" "unprognostic (1.98e-3)" "unprognostic (4.61e-2)" "unprognostic (1.69e-2)" "unprognostic (1.07e-1)" "unprognostic (1.92e-1)" "unprognostic (5.73e-2)" "unprognostic (1.84e-1)" "unprognostic (1.79e-1)" "unprognostic (5.83e-2)" "unprognostic (1.14e-1)" "unprognostic (1.74e-1)" "unprognostic (3.97e-2)" "unprognostic (2.96e-1)" "unprognostic (2.70e-1)" "unprognostic (4.78e-2)" "unprognostic (1.17e-1)" "unprognostic (1.75e-1)" "unprognostic (1.76e-1)" "unprognostic (3.96e-2)" "unprognostic (6.52e-2)" DNAJC18 MGC29463 ENSG00000170464 "DnaJ heat shock protein family (Hsp40) member C18" Q9H819 5 139408588-139444491 "Predicted intracellular proteins, Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 73.9" "Group enriched" "Detected in many" 5 "Early spermatids: 503.4;Late spermatids: 1921.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 8.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Lung - Endothelial cells, Minor Salivary Gland - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036538, HPA060154" Approved Approved "Cell Junctions,Cytosol" NA NA "Cluster 18: Non-specific - Translation" "Cluster 67: Testis - Mixed function" "Cluster 16: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 3 "Cell Junctions" Cytosol "HPA036538: , HPA060154: " "unprognostic (3.96e-3)" "unprognostic (5.71e-1)" "unprognostic (2.61e-1)" "unprognostic (5.59e-2)" "unprognostic (1.70e-1)" "unprognostic (1.35e-1)" "unprognostic (1.19e-1)" "unprognostic (1.21e-1)" "unprognostic (7.57e-2)" "potential prognostic unfavorable (1.39e-4)" "unprognostic (1.17e-3)" "unprognostic (1.66e-2)" "unprognostic (1.02e-1)" "unprognostic (7.74e-2)" "unprognostic (2.36e-1)" "unprognostic (1.43e-2)" "unprognostic (2.38e-1)" "unprognostic (1.29e-1)" "potential prognostic unfavorable (5.00e-8)" "unprognostic (1.27e-2)" "unprognostic (6.52e-2)" "unprognostic (1.16e-1)" "unprognostic (2.89e-2)" "unprognostic (2.46e-1)" "unprognostic (2.75e-2)" "unprognostic (2.49e-1)" "unprognostic (1.62e-1)" "unprognostic (7.42e-2)" DNAJC19 "Pam18, Tim14, TIMM14" ENSG00000205981 "DnaJ heat shock protein family (Hsp40) member C19" Q96DA6 3 180983697-180989774 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Translocation, Transport" Chaperone Cardiomyopathy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037782 Approved NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 97: Non-specific - Cellular respiration" 8 "HPA037782: " "unprognostic (6.98e-3)" "unprognostic (1.14e-1)" "unprognostic (9.00e-3)" "unprognostic (4.92e-3)" "unprognostic (1.41e-1)" "unprognostic (2.25e-3)" "unprognostic (2.21e-2)" "unprognostic (2.39e-1)" "unprognostic (2.01e-2)" "unprognostic (1.41e-2)" "potential prognostic favorable (6.90e-4)" "unprognostic (1.33e-1)" "unprognostic (2.37e-2)" "unprognostic (1.26e-1)" "unprognostic (4.35e-3)" "unprognostic (5.02e-2)" "unprognostic (4.21e-2)" "unprognostic (1.78e-2)" "unprognostic (2.37e-3)" "potential prognostic favorable (1.19e-5)" "unprognostic (3.25e-3)" "unprognostic (1.48e-2)" "unprognostic (2.69e-2)" "unprognostic (2.31e-2)" "unprognostic (4.37e-2)" "unprognostic (2.14e-1)" "unprognostic (2.64e-2)" "unprognostic (6.13e-2)" "unprognostic (1.83e-1)" "unprognostic (1.18e-1)" "unprognostic (4.81e-1)" DNAJC2 "MPHOSPH11, MPP11, ZRF1, ZUO1, zuotin" ENSG00000105821 "DnaJ heat shock protein family (Hsp40) member C2" Q99543 7 103312289-103344830 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Chaperone, Chromatin regulator" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 218.9;Late primary spermatocytes: 353.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 61.6" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020454 Approved Supported Cytosol NA Yes "Cluster 41: Basophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 39: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 145 Cytosol "HPA020454: " "unprognostic (2.19e-1)" "unprognostic (1.23e-1)" "unprognostic (3.70e-1)" "unprognostic (8.80e-2)" "unprognostic (3.14e-1)" "unprognostic (8.98e-2)" "unprognostic (4.90e-1)" "unprognostic (1.69e-1)" "unprognostic (8.11e-2)" "unprognostic (5.73e-3)" "unprognostic (1.22e-1)" "unprognostic (3.65e-2)" "unprognostic (1.22e-1)" "validated prognostic unfavorable (4.66e-5)" "validated prognostic unfavorable (4.90e-4)" "unprognostic (7.47e-3)" "unprognostic (3.16e-2)" "unprognostic (1.03e-2)" "unprognostic (2.36e-2)" "unprognostic (3.18e-2)" "unprognostic (3.56e-1)" "unprognostic (3.29e-2)" "unprognostic (3.65e-2)" "unprognostic (1.92e-2)" "unprognostic (6.40e-2)" "unprognostic (6.96e-2)" "unprognostic (3.43e-1)" "unprognostic (1.44e-1)" "unprognostic (2.31e-1)" "unprognostic (1.09e-1)" "unprognostic (8.12e-2)" DNAJC21 "DNAJA5, GS3, JJJ1" ENSG00000168724 "DnaJ heat shock protein family (Hsp40) member C21" Q5F1R6 5 34929559-34958964 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" HPA040789 Approved Supported Nucleoli,Cytosol NA NA "Cluster 32: Basophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" "Cluster 29: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 11 "Nucleoli, Cytosol" "HPA040789: " "unprognostic (6.88e-2)" "unprognostic (9.22e-2)" "unprognostic (2.66e-1)" "unprognostic (1.56e-2)" "unprognostic (2.07e-1)" "unprognostic (8.96e-2)" "unprognostic (6.94e-2)" "unprognostic (3.30e-1)" "unprognostic (8.03e-2)" "unprognostic (1.42e-2)" "potential prognostic favorable (1.94e-6)" "unprognostic (3.81e-2)" "unprognostic (2.19e-2)" "potential prognostic unfavorable (1.96e-5)" "unprognostic (1.60e-2)" "unprognostic (2.32e-2)" "unprognostic (7.05e-2)" "unprognostic (1.68e-1)" "unprognostic (2.62e-1)" "unprognostic (2.14e-3)" "unprognostic (1.89e-1)" "potential prognostic unfavorable (1.29e-4)" "unprognostic (2.32e-3)" "unprognostic (9.79e-2)" "unprognostic (8.78e-2)" "unprognostic (6.90e-2)" "unprognostic (6.19e-2)" "unprognostic (3.02e-1)" "unprognostic (3.73e-1)" "unprognostic (8.15e-2)" "unprognostic (2.66e-1)" DNAJC22 "FLJ13236, wus" ENSG00000178401 "DnaJ heat shock protein family (Hsp40) member C22" Q8N4W6 12 49346888-49357546 "Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "liver: 17.3" "Cell type enhanced" "Detected in many" "Cholangiocytes: 57.9;Colonocytes: 44.3;Enteric stem cells: 27.8;Enteric transient amplifying cells: 34.4;Enterocytes: 67.3;Epididymal efferent duct absorptive cells: 41.7;Gastric chief cells: 26.2;Goblet cells: 44.3;Hepatocytes: 84.4;Mucous neck cells: 37.7;Neuroendocrine cells: 32.0;Proximal tubule cells: 27.3" "Cell type enhanced" "Detected in many" "lower rhombic lip: 5.8;oligodendrocyte: 12.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Adrenal gland - Fibroblasts, Breast - Breast glandular cells, Colon - Colon enterocytes, Kidney - Proximal tubular cells, Skin - Outer root sheath cells" "Region enhanced" "Detected in single" "midbrain: 1.2" "Low region specificity" "Detected in all" HPA039953 Approved Vesicles NA NA "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 43: Hindbrain - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 1 Vesicles "HPA039953: " "unprognostic (1.77e-2)" "unprognostic (4.17e-1)" "unprognostic (1.60e-2)" "unprognostic (2.61e-1)" "unprognostic (2.32e-1)" "unprognostic (1.05e-2)" "potential prognostic unfavorable (2.31e-4)" "unprognostic (2.04e-3)" "unprognostic (7.49e-2)" "unprognostic (1.21e-2)" "unprognostic (1.27e-1)" "unprognostic (6.27e-2)" "potential prognostic unfavorable (2.08e-4)" "unprognostic (1.40e-3)" "unprognostic (3.08e-1)" "unprognostic (4.40e-3)" "unprognostic (3.42e-2)" "unprognostic (6.66e-2)" "unprognostic (3.25e-1)" "unprognostic (8.95e-2)" "unprognostic (2.71e-3)" "unprognostic (1.62e-1)" "unprognostic (3.87e-2)" "unprognostic (3.90e-1)" "unprognostic (6.36e-2)" DNAJC24 "DPH4, JJJ3, ZCSL3" ENSG00000170946 "DnaJ heat shock protein family (Hsp40) member C24" Q6P3W2 11 31369840-31432835 "Predicted intracellular proteins" "Electron transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 218.9;Late primary spermatocytes: 139.1;Late spermatids: 356.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020025, HPA025237" Approved Approved Cytosol NA NA "Cluster 27: T-cells - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 24: Non-specific - Unknown function" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 4 Cytosol "HPA020025: , HPA025237: " "unprognostic (9.60e-2)" "unprognostic (4.40e-2)" "unprognostic (6.51e-2)" "unprognostic (2.30e-2)" "unprognostic (2.36e-3)" "unprognostic (5.90e-2)" "unprognostic (3.30e-1)" "unprognostic (3.24e-2)" "unprognostic (1.56e-1)" "unprognostic (7.45e-3)" "unprognostic (1.00e-1)" "unprognostic (1.40e-1)" "unprognostic (3.22e-1)" "potential prognostic unfavorable (3.99e-4)" "unprognostic (1.79e-2)" "unprognostic (4.02e-2)" "unprognostic (1.04e-1)" "unprognostic (1.88e-1)" "unprognostic (2.16e-1)" "unprognostic (9.95e-2)" "potential prognostic unfavorable (4.94e-5)" "unprognostic (1.27e-1)" "unprognostic (2.84e-3)" "unprognostic (3.22e-1)" "unprognostic (1.60e-2)" "unprognostic (9.53e-2)" "unprognostic (2.97e-2)" "unprognostic (1.03e-1)" "unprognostic (4.93e-1)" "unprognostic (2.73e-2)" "unprognostic (1.23e-1)" DNAJC25 bA16L21.2.1 ENSG00000059769 "DnaJ heat shock protein family (Hsp40) member C25" Q9H1X3 9 111631334-111654351 "Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 30.0" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 24.3;Brain inhibitory neurons: 23.7;Choroid plexus epithelial cells: 36.3;Ependymal cells: 36.3;Epididymal principal cells: 18.7;Hepatocytes: 25.9;Microglia: 18.2;Other brain neurons: 21.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019122 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 17: Choroid plexus - Cilium" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 22: Non-specific - Basic cellular functions" 11 Nucleoplasm Cytosol "HPA019122: " "unprognostic (1.13e-1)" "unprognostic (1.16e-2)" "unprognostic (1.09e-2)" "unprognostic (2.56e-3)" "unprognostic (1.83e-1)" "unprognostic (6.84e-3)" "unprognostic (1.57e-1)" "unprognostic (1.20e-3)" "unprognostic (1.76e-3)" "unprognostic (1.99e-1)" "potential prognostic favorable (5.73e-5)" "unprognostic (1.72e-1)" "unprognostic (1.25e-1)" "unprognostic (7.00e-2)" "unprognostic (1.09e-2)" "unprognostic (4.67e-2)" "unprognostic (1.44e-1)" "unprognostic (1.10e-2)" "unprognostic (3.59e-3)" "unprognostic (4.98e-3)" "unprognostic (4.06e-2)" "unprognostic (1.51e-1)" "potential prognostic unfavorable (5.33e-4)" "unprognostic (1.27e-1)" "unprognostic (3.98e-3)" "unprognostic (3.44e-1)" "unprognostic (4.94e-2)" "unprognostic (1.21e-1)" "unprognostic (2.51e-1)" "unprognostic (1.28e-1)" "unprognostic (1.77e-3)" DNAJC25-GNG10 ENSG00000244115 "DNAJC25-GNG10 readthrough" 9 111631386-111670229 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enteric transient amplifying cells: 6.5;Enterocytes: 7.8;Gastric chief cells: 7.6;Kupffer cells: 7.2;Mucous neck cells: 8.7;Neutrophils: 15.8;Parietal cells: 10.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 8 "neutrophil: 73.4" "Lineage enriched" "Detected in all" 11 "granulocytes: 73.4" "Low cancer specificity" "Detected in all" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 36: Brain & Liver - Signaling" "Cluster 21: Non-specific - Metabolism" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 15: Non-specific - Protein processing" "potential prognostic unfavorable (9.89e-4)" "unprognostic (1.53e-1)" "unprognostic (4.35e-2)" "unprognostic (8.75e-2)" "unprognostic (1.96e-1)" "unprognostic (1.31e-2)" "potential prognostic unfavorable (9.11e-5)" "unprognostic (1.67e-2)" "potential prognostic favorable (2.64e-4)" "unprognostic (5.93e-2)" "potential prognostic unfavorable (1.37e-4)" "unprognostic (3.11e-2)" "unprognostic (2.01e-3)" "unprognostic (6.78e-2)" "unprognostic (1.17e-1)" "unprognostic (1.77e-1)" "unprognostic (1.41e-1)" "unprognostic (7.52e-2)" "unprognostic (7.29e-2)" "unprognostic (3.95e-1)" "unprognostic (1.80e-1)" "unprognostic (4.18e-2)" "unprognostic (6.87e-2)" "unprognostic (1.29e-1)" "unprognostic (1.35e-1)" "unprognostic (2.39e-1)" DNAJC27 "RabJS, RBJ" ENSG00000115137 "DnaJ heat shock protein family (Hsp40) member C27" Q9NZQ0 2 24943636-24972094 "Predicted intracellular proteins" Oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 20.8" "Cell type enhanced" "Detected in all" "Granulosa cells: 128.1;Vascular smooth muscle cells: 109.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036815, HPA036816" Uncertain Approved Cytosol NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 103: Non-specific - Basic cellular processes" 6 Cytosol "HPA036815: , HPA036816: " "unprognostic (6.83e-3)" "unprognostic (6.10e-2)" "unprognostic (1.36e-2)" "unprognostic (8.97e-2)" "unprognostic (2.24e-2)" "unprognostic (2.82e-1)" "unprognostic (2.16e-1)" "unprognostic (8.74e-2)" "unprognostic (1.36e-2)" "unprognostic (7.00e-2)" "validated prognostic favorable (5.57e-5)" "validated prognostic favorable (1.99e-4)" "unprognostic (1.36e-1)" "unprognostic (1.08e-1)" "unprognostic (4.92e-3)" "unprognostic (2.20e-1)" "unprognostic (1.91e-1)" "unprognostic (4.50e-1)" "unprognostic (2.23e-1)" "unprognostic (1.27e-1)" "unprognostic (1.04e-3)" "unprognostic (2.16e-3)" "unprognostic (2.76e-2)" "unprognostic (1.30e-2)" "unprognostic (1.91e-1)" "unprognostic (1.32e-1)" "unprognostic (3.16e-1)" "unprognostic (3.39e-1)" "unprognostic (1.78e-2)" "unprognostic (2.20e-1)" DNAJC28 "C21orf55, C21orf78" ENSG00000177692 "DnaJ heat shock protein family (Hsp40) member C28" Q9NX36 21 33485530-33491716 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 6.3" "Cell type enhanced" "Detected in some" "Astrocytes: 3.0;Bergmann glia: 5.5;Brain excitatory neurons: 4.4;Brain inhibitory neurons: 4.0;Choroid plexus epithelial cells: 5.1;Distal convoluted tubule cells: 2.7;Early spermatids: 3.1;Late primary spermatocytes: 3.2;Loop of henle epithelial cells: 3.3;Oligodendrocyte progenitor cells: 2.6;Oligodendrocytes: 3.7;Other brain neurons: 4.1;Podocytes: 3.6;Proximal tubule cells: 4.4;Renal collecting duct principal cells: 2.6;Renal connecting tubule cells: 3.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018003, HPA030076, HPA077153" Approved Approved "Nucleoplasm,Nuclear bodies,Centrosome,Cytosol" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 9: Non-specific - Receptor signaling" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 98: Neurons - Neurotransmission & signaling" 1 "Nucleoplasm, Centrosome" "Nuclear bodies, Cytosol" "HPA018003: , HPA030076: , HPA077153: " "unprognostic (3.31e-2)" "unprognostic (1.25e-1)" "unprognostic (2.92e-1)" "potential prognostic favorable (6.27e-4)" "unprognostic (7.45e-3)" "unprognostic (2.09e-2)" "unprognostic (2.01e-1)" "unprognostic (1.54e-2)" DNAJC3 "ERdj6, HP58, P58, p58(IPK), P58IPK, PRKRI" ENSG00000102580 "DnaJ heat shock protein family (Hsp40) member C3" Q13217 13 95677139-95794988 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Antiviral defense, Stress response, Translation regulation, Unfolded protein response" "Chaperone, Repressor" "Deafness, Diabetes mellitus, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 694.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039336, HPA041326" Uncertain Approved "Endoplasmic reticulum" "Intracellular and membrane" Defense NA NA 1600000 "Cluster 41: Basophils - Unknown function" "Cluster 22: Epididymis - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 34 "Endoplasmic reticulum" "HPA039336: , HPA041326: " "unprognostic (2.17e-1)" "unprognostic (2.87e-2)" "unprognostic (1.63e-1)" "unprognostic (6.95e-3)" "unprognostic (7.14e-2)" "unprognostic (1.24e-1)" "unprognostic (1.28e-1)" "unprognostic (1.13e-3)" "unprognostic (4.07e-2)" "unprognostic (1.09e-2)" "potential prognostic favorable (2.48e-6)" "unprognostic (2.34e-2)" "unprognostic (3.07e-1)" "unprognostic (1.34e-1)" "unprognostic (1.21e-1)" "unprognostic (1.76e-1)" "unprognostic (4.24e-2)" "unprognostic (2.42e-3)" "unprognostic (2.73e-1)" "unprognostic (2.81e-1)" "unprognostic (1.17e-2)" "unprognostic (2.17e-1)" "unprognostic (6.29e-2)" "unprognostic (3.49e-1)" "unprognostic (1.02e-1)" "unprognostic (7.91e-2)" "unprognostic (2.73e-2)" "unprognostic (1.06e-1)" "unprognostic (1.34e-1)" "unprognostic (1.67e-2)" "unprognostic (4.71e-2)" DNAJC30 WBSCR18 ENSG00000176410 "DnaJ heat shock protein family (Hsp40) member C30" Q96LL9 7 73680918-73683453 "Disease related genes, Human disease related genes, Predicted membrane proteins" "ATP synthesis" Chaperone "Disease variant, Leber hereditary optic neuropathy, Primary mitochondrial disease, Williams-Beuren syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 124.4;Late primary spermatocytes: 133.2;Late spermatids: 360.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017318 Supported NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 70: Non-specific - Protein processing" "Cluster 24: Neurons - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 82 "HPA017318: " "unprognostic (2.76e-1)" "unprognostic (6.01e-2)" "unprognostic (9.84e-2)" "unprognostic (9.66e-2)" "unprognostic (9.03e-2)" "unprognostic (1.43e-1)" "potential prognostic unfavorable (1.18e-4)" "unprognostic (3.12e-3)" "unprognostic (1.65e-3)" "unprognostic (1.91e-1)" "potential prognostic favorable (3.57e-7)" "unprognostic (8.82e-2)" "potential prognostic favorable (2.40e-9)" "unprognostic (2.95e-1)" "unprognostic (9.42e-2)" "unprognostic (6.13e-2)" "unprognostic (2.23e-1)" "unprognostic (2.03e-2)" "unprognostic (1.74e-1)" "unprognostic (7.83e-2)" "unprognostic (1.86e-1)" "potential prognostic favorable (5.56e-4)" "unprognostic (5.12e-2)" "unprognostic (3.22e-1)" "unprognostic (3.04e-2)" "unprognostic (2.35e-1)" "unprognostic (2.28e-1)" "unprognostic (1.55e-1)" "unprognostic (2.60e-1)" "unprognostic (2.07e-1)" "unprognostic (8.81e-2)" DNAJC4 "HSPF2, MCG18" ENSG00000110011 "DnaJ heat shock protein family (Hsp40) member C4" Q9NNZ3 11 64230278-64234286 "Predicted intracellular proteins, Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 231.9" "Cell type enriched" "Detected in many" 8 "Late spermatids: 6443.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011947 Uncertain NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 21: Testis - Mixed function" "Cluster 18: Non-specific - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 5 "HPA011947: " "unprognostic (1.89e-1)" "unprognostic (1.23e-2)" "unprognostic (3.74e-2)" "unprognostic (5.20e-2)" "unprognostic (5.76e-2)" "unprognostic (9.22e-2)" "unprognostic (1.41e-1)" "unprognostic (2.58e-1)" "unprognostic (3.79e-1)" "unprognostic (1.53e-2)" "unprognostic (1.31e-2)" "unprognostic (1.28e-2)" "potential prognostic favorable (4.97e-4)" "unprognostic (3.51e-2)" "unprognostic (3.67e-1)" "unprognostic (9.37e-2)" "unprognostic (7.99e-2)" "unprognostic (2.21e-1)" "unprognostic (1.23e-1)" "unprognostic (2.25e-3)" "unprognostic (2.17e-1)" "unprognostic (2.70e-2)" "unprognostic (3.58e-1)" "unprognostic (2.41e-1)" "unprognostic (6.27e-2)" "unprognostic (1.07e-1)" "unprognostic (2.33e-1)" "unprognostic (2.11e-1)" "unprognostic (1.58e-1)" "unprognostic (2.61e-1)" "unprognostic (2.52e-1)" DNAJC5 "CLN4, DNAJC5A, FLJ00118, FLJ13070" ENSG00000101152 "DnaJ heat shock protein family (Hsp40) member C5" Q9H3Z4 20 63895126-63936031 "Disease related genes, Human disease related genes, Predicted membrane proteins" Chaperone "Disease variant, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 320.5;Late spermatids: 200.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012737, HPA012781, HPA013154" Approved Supported "Golgi apparatus,Vesicles,Perinuclear theca,Principal piece,End piece" NA NA 8000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 1: Neurons - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 102: Non-specific - Mixed function" 34 Vesicles "Golgi apparatus, Perinuclear theca, Principal piece, End piece" "HPA012737: , HPA012781: , HPA013154: " "unprognostic (4.12e-2)" "unprognostic (1.14e-2)" "unprognostic (1.66e-2)" "unprognostic (1.35e-2)" "unprognostic (1.28e-1)" "unprognostic (3.75e-2)" "unprognostic (3.12e-1)" "unprognostic (6.91e-2)" "unprognostic (1.35e-1)" "unprognostic (2.89e-1)" "potential prognostic favorable (5.58e-4)" "unprognostic (1.36e-1)" "unprognostic (1.72e-2)" "potential prognostic unfavorable (9.79e-5)" "unprognostic (8.14e-3)" "unprognostic (2.24e-3)" "unprognostic (4.79e-2)" "unprognostic (2.96e-2)" "unprognostic (2.84e-1)" "unprognostic (2.04e-2)" "unprognostic (1.10e-1)" "unprognostic (2.77e-3)" "potential prognostic unfavorable (3.71e-4)" "unprognostic (2.33e-2)" "unprognostic (8.82e-2)" "unprognostic (4.15e-2)" "unprognostic (2.68e-1)" "unprognostic (5.46e-2)" "unprognostic (1.32e-1)" "unprognostic (8.35e-2)" "unprognostic (8.38e-2)" DNAJC5B "CSP-beta, MGC26226" ENSG00000147570 "DnaJ heat shock protein family (Hsp40) member C5 beta" Q9UF47 8 66021553-66101245 "Predicted intracellular proteins, Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 57.9" "Group enriched" "Detected in some" 7 "Early spermatids: 1214.9;Late spermatids: 4363.1" "Group enriched" "Detected in some" 6 "CGE interneuron: 3.3;lower rhombic lip: 1.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "white matter: 1.2" "Immune cell enhanced" "Detected in some" "memory B-cell: 5.8" "Lineage enriched" "Detected in many" 5 "B-cells: 5.8" "Cancer enhanced" "Detected in some" "lymphoma: 15.5;Rhabdoid: 5.2" "Lung - Macrophages, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 39: Testis - Nuclear processes" "Cluster 30: White matter - Myelination" "Cluster 55: Lymphoma - Immune response" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 14 "unprognostic (2.18e-1)" "unprognostic (8.93e-2)" "unprognostic (3.90e-2)" "unprognostic (2.19e-2)" "unprognostic (5.02e-2)" "unprognostic (6.10e-1)" "unprognostic (1.70e-1)" "unprognostic (1.85e-1)" "unprognostic (3.27e-3)" "unprognostic (1.04e-2)" "unprognostic (1.31e-1)" "unprognostic (2.52e-1)" "unprognostic (8.42e-2)" "unprognostic (8.30e-3)" "unprognostic (5.64e-3)" "unprognostic (1.27e-2)" "unprognostic (1.85e-1)" "unprognostic (8.78e-3)" "unprognostic (3.15e-1)" DNAJC5G "CSP-gamma, FLJ40417" ENSG00000163793 "DnaJ heat shock protein family (Hsp40) member C5 gamma" Q8N7S2 2 27275433-27281499 "Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "epididymis: 44.2;testis: 21.3" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 30.6;Differentiating spermatogonia: 37.7;Early primary spermatocytes: 136.6;Early spermatids: 60.9;Epididymal principal cells: 180.2;Late primary spermatocytes: 184.1;Late spermatids: 122.1;Sertoli cells: 44.8;Undifferentiated spermatogonia: 42.5" "Group enriched" "Detected in many" 4 "amygdala excitatory: 14.3;deep-layer intratelencephalic: 22.2;hippocampal dentate gyrus: 24.5;miscellaneous: 6.3;upper-layer intratelencephalic: 24.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA041445 Approved NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" "HPA041445: " "unprognostic (4.77e-3)" "unprognostic (2.14e-1)" "unprognostic (3.09e-2)" "unprognostic (1.49e-1)" "unprognostic (2.26e-1)" DNAJC6 "KIAA0473, PARK19" ENSG00000116675 "DnaJ heat shock protein family (Hsp40) member C6" O75061 1 65248219-65415871 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Chaperone, Hydrolase, Protein phosphatase" "Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 90.0;retina: 48.9" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 320.7;Brain inhibitory neurons: 247.6;Corticotrophs: 196.4;Erythrocyte progenitors: 216.8;Gonadotrophs: 202.5;Lactotrophs: 256.5;Megakaryocyte-Erythroid progenitors: 209.2;Oligodendrocyte progenitor cells: 187.8;Oligodendrocytes: 1219.5;Other brain neurons: 306.9;Retinal amacrine cells: 184.6;Retinal horizontal cells: 202.3;Somatotrophs: 183.5;Thyrotrophs: 216.9" "Cell type enhanced" "Detected in all" "oligodendrocyte: 1616.5" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 12.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 34.4" "Colon - Colon enteroendocrine cells, Skin - Hair cortex cells, Skin - Inner root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031182, HPA054917" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 80: Oligodendrocytes - Myelination" 6 Cytosol "Nucleoplasm, Plasma membrane" "HPA031182: , HPA054917: " "unprognostic (8.59e-2)" "unprognostic (1.91e-1)" "unprognostic (9.04e-2)" "unprognostic (6.36e-2)" "unprognostic (4.25e-1)" "potential prognostic favorable (8.81e-4)" "unprognostic (2.95e-2)" "potential prognostic favorable (1.17e-4)" "unprognostic (5.21e-3)" "unprognostic (9.94e-2)" "potential prognostic unfavorable (5.02e-4)" "unprognostic (3.41e-2)" "unprognostic (1.96e-2)" "unprognostic (2.85e-2)" "unprognostic (2.35e-1)" "unprognostic (2.05e-1)" "unprognostic (4.84e-1)" "unprognostic (1.28e-2)" "unprognostic (8.05e-2)" "unprognostic (2.30e-1)" "unprognostic (8.68e-2)" "unprognostic (1.78e-1)" "unprognostic (1.02e-1)" "unprognostic (2.58e-2)" "unprognostic (1.19e-1)" "unprognostic (3.24e-1)" DNAJC7 "TPR2, TTC2" ENSG00000168259 "DnaJ heat shock protein family (Hsp40) member C7" Q99615 17 41976421-42021376 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023015, HPA052395" Approved Supported Nucleoplasm,Cytosol NA NA 11000 "Cluster 13: Non-specific - Mitochondria" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 130 "Nucleoplasm, Cytosol" "HPA023015: , HPA052395: " "unprognostic (5.09e-2)" "unprognostic (4.44e-2)" "unprognostic (3.05e-1)" "unprognostic (1.89e-2)" "unprognostic (5.22e-2)" "unprognostic (2.07e-1)" "unprognostic (1.33e-1)" "potential prognostic favorable (2.06e-4)" "unprognostic (9.22e-3)" "unprognostic (3.12e-2)" "unprognostic (7.57e-2)" "unprognostic (3.34e-2)" "unprognostic (2.76e-2)" "validated prognostic unfavorable (3.60e-4)" "validated prognostic unfavorable (7.32e-5)" "unprognostic (7.98e-2)" "unprognostic (2.51e-3)" "unprognostic (2.53e-1)" "unprognostic (2.13e-1)" "potential prognostic unfavorable (6.37e-4)" "unprognostic (1.38e-1)" "unprognostic (5.44e-2)" "potential prognostic unfavorable (3.09e-5)" "unprognostic (5.87e-2)" "unprognostic (1.14e-1)" "unprognostic (2.02e-1)" "unprognostic (1.78e-1)" "unprognostic (1.98e-2)" "unprognostic (2.21e-1)" "unprognostic (6.14e-2)" "unprognostic (2.80e-2)" DNAJC8 SPF31 ENSG00000126698 "DnaJ heat shock protein family (Hsp40) member C8" O75937 1 28199456-28233029 "Essential proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026275, HPA026283" Approved Enhanced "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes NA "Cluster 29: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 70 Nucleoplasm "Cytokinetic bridge, Cytosol" "HPA026275: , HPA026283: " "unprognostic (9.60e-2)" "unprognostic (2.43e-2)" "potential prognostic unfavorable (9.79e-5)" "unprognostic (2.33e-1)" "unprognostic (7.97e-2)" "unprognostic (4.00e-1)" "unprognostic (8.57e-2)" "unprognostic (7.62e-2)" "unprognostic (1.69e-1)" "unprognostic (9.45e-3)" "potential prognostic favorable (2.63e-9)" "unprognostic (3.55e-2)" "unprognostic (3.30e-2)" "validated prognostic unfavorable (3.18e-4)" "validated prognostic unfavorable (8.13e-4)" "unprognostic (1.02e-1)" "unprognostic (1.71e-2)" "unprognostic (1.28e-1)" "unprognostic (1.95e-1)" "unprognostic (1.78e-1)" "unprognostic (2.38e-1)" "unprognostic (1.04e-1)" "unprognostic (2.30e-1)" "unprognostic (4.24e-2)" "unprognostic (2.26e-1)" "unprognostic (2.53e-2)" "unprognostic (6.79e-3)" "unprognostic (1.75e-1)" "unprognostic (6.00e-2)" "unprognostic (2.50e-1)" "unprognostic (2.50e-2)" DNAJC9 "JDD1, SB73" ENSG00000213551 "DnaJ heat shock protein family (Hsp40) member C9" Q8WXX5 10 73183362-73247255 "Essential proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 86.6" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 257.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035215, HPA035216" Supported Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 89000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 37: Neurons - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 27: Non-specific - Cell proliferation" 47 Nucleoplasm "Plasma membrane, Cytosol" "HPA035215: , HPA035216: " "unprognostic (1.22e-1)" "unprognostic (1.92e-2)" "unprognostic (2.62e-3)" "unprognostic (1.06e-3)" "unprognostic (3.34e-1)" "unprognostic (3.78e-1)" "unprognostic (1.17e-1)" "potential prognostic favorable (1.98e-6)" "unprognostic (1.19e-1)" "unprognostic (3.77e-1)" "unprognostic (1.50e-2)" "unprognostic (8.61e-2)" "unprognostic (4.07e-2)" "validated prognostic unfavorable (6.90e-4)" "validated prognostic unfavorable (4.33e-4)" "potential prognostic unfavorable (1.12e-4)" "unprognostic (4.38e-2)" "unprognostic (2.18e-1)" "unprognostic (2.72e-1)" "unprognostic (2.61e-1)" "unprognostic (1.72e-1)" "unprognostic (1.80e-2)" "unprognostic (1.72e-3)" "unprognostic (1.40e-3)" "unprognostic (1.55e-1)" "unprognostic (4.45e-2)" "unprognostic (1.39e-1)" "unprognostic (1.32e-2)" "unprognostic (1.69e-1)" "unprognostic (2.34e-1)" "unprognostic (1.39e-1)" DNAL1 "1700010H15RiK, C14orf168, CILD16, MGC12435" ENSG00000119661 "Dynein axonemal light chain 1" Q4LDG9 14 73644875-73703732 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Motor protein" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 51.0" "Cell type enhanced" "Detected in many" "Early spermatids: 306.5;Endometrial ciliated cells: 161.4;Ependymal cells: 116.2;Epididymal efferent duct ciliated cells: 138.1;Fallopian tube ciliated cells: 188.8;Late primary spermatocytes: 521.6;Respiratory ciliated cells: 231.7" "Cell type enhanced" "Detected in all" "ependymal cell: 144.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Skin - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053129, HPA060974" Approved Approved "Nucleoplasm,Centriolar satellite,Centrosome,Basal body,Cytosol,Acrosome,Mid piece,Principal piece,End piece" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 29: Forebrain - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 107: Ciliated cells - Cilia assembly & function" 2 "Nucleoplasm, Basal body, Cytosol, Principal piece" "Centriolar satellite, Centrosome, Acrosome, Mid piece, End piece" "HPA053129: , HPA060974: " "unprognostic (1.44e-1)" "unprognostic (1.01e-1)" "unprognostic (1.85e-1)" "unprognostic (1.28e-1)" "unprognostic (7.29e-2)" "unprognostic (5.13e-2)" "unprognostic (2.27e-1)" "unprognostic (2.20e-2)" "unprognostic (3.70e-3)" "potential prognostic unfavorable (1.04e-4)" "potential prognostic favorable (1.58e-4)" "unprognostic (1.28e-2)" "unprognostic (1.30e-3)" "potential prognostic unfavorable (2.72e-4)" "unprognostic (1.31e-1)" "unprognostic (5.33e-2)" "unprognostic (3.74e-1)" "unprognostic (2.32e-1)" "unprognostic (2.42e-1)" "unprognostic (4.70e-1)" "potential prognostic unfavorable (6.28e-6)" "unprognostic (4.44e-2)" "unprognostic (2.80e-3)" "unprognostic (3.04e-2)" "unprognostic (1.02e-2)" "unprognostic (9.86e-2)" "unprognostic (8.00e-2)" "unprognostic (3.57e-2)" "unprognostic (1.84e-1)" "unprognostic (5.57e-2)" "unprognostic (2.30e-1)" DNAL4 "dJ327J16, PIG27" ENSG00000100246 "Dynein axonemal light chain 4" O96015 22 38778508-38794198 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in some" 6 "Late spermatids: 246.4" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" HPA003647 Approved Approved "Nucleoplasm,Nucleoli,Primary cilium transition zone,Centrosome,Basal body,Cytosol,Acrosome,Equatorial segment,Perinuclear theca,Calyx,Principal piece" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 21: Testis - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 24 "Centrosome, Basal body, Acrosome" "Nucleoplasm, Nucleoli, Primary cilium transition zone, Cytosol, Equatorial segment, Perinuclear theca, Calyx, Principal piece" "HPA003647: " "unprognostic (3.31e-1)" "unprognostic (4.68e-2)" "unprognostic (3.51e-1)" "unprognostic (8.89e-2)" "unprognostic (3.34e-1)" "unprognostic (1.08e-1)" "unprognostic (6.74e-2)" "unprognostic (3.27e-1)" "unprognostic (1.42e-1)" "unprognostic (5.67e-2)" "potential prognostic favorable (1.68e-5)" "unprognostic (3.40e-2)" "unprognostic (3.68e-2)" "unprognostic (2.42e-3)" "unprognostic (8.40e-3)" "unprognostic (2.94e-2)" "unprognostic (2.81e-1)" "unprognostic (1.35e-1)" "unprognostic (2.26e-1)" "unprognostic (3.95e-2)" "unprognostic (1.96e-1)" "unprognostic (3.99e-2)" "unprognostic (1.09e-2)" "unprognostic (2.53e-1)" "unprognostic (7.75e-2)" "unprognostic (4.67e-1)" "unprognostic (5.59e-2)" "unprognostic (4.24e-2)" "unprognostic (8.28e-2)" "unprognostic (7.43e-3)" "unprognostic (3.62e-3)" DNALI1 "dJ423B22.5, hp28, P28" ENSG00000163879 "Dynein axonemal light intermediate chain 1" O14645 1 37556919-37566857 "Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 75.0;fallopian tube: 51.2" "Cell type enhanced" "Detected in many" "Early spermatids: 657.8;Endometrial ciliated cells: 336.5;Epididymal efferent duct ciliated cells: 363.9;Fallopian tube ciliated cells: 391.2;Late primary spermatocytes: 514.2;Late spermatids: 1404.5;Respiratory ciliated cells: 447.7" "Group enriched" "Detected in many" 5 "choroid plexus epithelial cell: 70.6;ependymal cell: 177.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 8.1" "Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA028305, HPA031633" Enhanced Supported "Nucleoplasm,Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Mid piece,Principal piece,End piece" Yes NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 63 "Primary cilium, Mid piece, Principal piece, End piece" "Nucleoplasm, Microtubules, Cytokinetic bridge, Mitotic spindle" "HPA028305: , HPA031633: " "unprognostic (1.87e-2)" "unprognostic (3.31e-1)" "unprognostic (8.36e-2)" "unprognostic (3.13e-2)" "unprognostic (9.88e-2)" "unprognostic (2.69e-1)" "unprognostic (1.55e-1)" "unprognostic (3.57e-2)" "unprognostic (1.10e-1)" "validated prognostic favorable (4.56e-6)" "validated prognostic favorable (1.14e-4)" "unprognostic (5.38e-3)" "unprognostic (3.17e-2)" "unprognostic (1.21e-1)" "potential prognostic favorable (3.17e-4)" "unprognostic (2.50e-1)" "unprognostic (9.15e-2)" "unprognostic (2.64e-1)" "unprognostic (1.96e-2)" "unprognostic (1.72e-1)" "unprognostic (3.03e-2)" "unprognostic (1.47e-1)" "unprognostic (3.92e-2)" "unprognostic (2.42e-1)" "unprognostic (1.02e-1)" "unprognostic (1.76e-1)" "unprognostic (6.72e-2)" "unprognostic (1.14e-1)" "unprognostic (6.83e-2)" "unprognostic (1.62e-1)" DNASE1 DNL1 ENSG00000213918 "Deoxyribonuclease 1" P24855 16 3611728-3680143 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" Apoptosis "Actin-binding, Endonuclease, Hydrolase, Nuclease" "Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "intestine: 112.5;kidney: 63.2;pancreas: 145.6" "Cell type enriched" "Detected in all" 4 "Enterocytes: 688.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 46.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Ascending Loop of Henle cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA010703 Enhanced Supported Vesicles "Secreted to digestive system" Enzyme NA NA 710000 "Cluster 20: Non-specific - DNA binding" "Cluster 60: Stomach - Digestion" "Cluster 6: Non-specific - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 1: Enterocytes - Absorption and Digestion" Vesicles "HPA010703: " "unprognostic (3.73e-1)" "unprognostic (8.01e-3)" "unprognostic (8.80e-2)" "unprognostic (1.26e-1)" "unprognostic (2.07e-2)" "unprognostic (1.83e-1)" "unprognostic (1.99e-1)" "unprognostic (6.47e-3)" "unprognostic (2.11e-2)" "unprognostic (4.23e-1)" "unprognostic (2.23e-3)" "unprognostic (1.39e-2)" "unprognostic (3.05e-1)" "unprognostic (2.61e-2)" "unprognostic (1.48e-1)" "unprognostic (1.26e-1)" "unprognostic (2.49e-1)" "unprognostic (1.91e-1)" "unprognostic (5.27e-3)" "unprognostic (1.44e-1)" "unprognostic (9.78e-2)" "unprognostic (3.50e-3)" "unprognostic (1.16e-3)" "unprognostic (1.10e-3)" "unprognostic (1.77e-1)" "unprognostic (3.42e-2)" "unprognostic (2.80e-1)" "unprognostic (4.63e-2)" "unprognostic (1.36e-1)" "unprognostic (3.55e-1)" "unprognostic (5.62e-2)" DNASE1L1 "DNAS1L1, DNASEX, DNL1L, XIB" ENSG00000013563 "Deoxyribonuclease 1 like 1" P49184 X 154401236-154412112 "Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 136.0;tongue: 88.4" "Cell type enriched" "Detected in many" 5 "Cardiomyocytes: 295.6" "Cell type enhanced" "Detected in all" "endothelial cell: 21.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072635 Approved "Intracellular and membrane" Enzyme NA NA 33000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 36: Non-specific - mRNA processing" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 71 "HPA072635: " "unprognostic (5.87e-2)" "unprognostic (3.65e-3)" "unprognostic (3.28e-1)" "unprognostic (8.88e-2)" "unprognostic (6.91e-2)" "unprognostic (3.07e-2)" "unprognostic (3.56e-2)" "unprognostic (3.83e-2)" "unprognostic (1.77e-3)" "unprognostic (4.87e-2)" "potential prognostic favorable (2.54e-5)" "unprognostic (4.44e-3)" "unprognostic (6.96e-2)" "unprognostic (6.63e-2)" "unprognostic (1.45e-1)" "unprognostic (8.15e-2)" "unprognostic (3.22e-2)" "unprognostic (8.35e-3)" "unprognostic (2.07e-2)" "unprognostic (2.95e-1)" "unprognostic (5.63e-2)" "unprognostic (3.72e-2)" "unprognostic (2.03e-1)" "unprognostic (3.81e-1)" "unprognostic (2.10e-1)" "unprognostic (7.61e-2)" "unprognostic (9.17e-2)" "unprognostic (1.26e-1)" "unprognostic (5.40e-2)" "unprognostic (1.90e-1)" "unprognostic (2.48e-2)" DNASE1L2 DNAS1L2 ENSG00000167968 "Deoxyribonuclease 1 like 2" Q92874 16 2235816-2238711 "Predicted secreted proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 16.2;skin 1: 43.9" "Cell type enhanced" "Detected in some" "Astrocytes: 3.7;Brain excitatory neurons: 2.8;Brain inhibitory neurons: 3.3;Epididymal principal cells: 9.0;Gonadotrophs: 2.3;Neuroendocrine cells: 2.5;Oligodendrocytes: 2.6;Other brain neurons: 2.8;Respiratory ionocytes: 2.5;Thymic myoid cells: 4.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skin - Hair cortex cells, Skin - Inner root sheath cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA044714 Approved Mitochondria "Secreted in other tissues" Enzyme NA NA "Cluster 2: Non-specific - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 3: Rhabdoid - Membrane components" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 8 Mitochondria "HPA044714: " "unprognostic (8.98e-2)" "unprognostic (1.54e-2)" "unprognostic (3.09e-2)" "potential prognostic favorable (2.49e-4)" "unprognostic (1.99e-2)" "unprognostic (1.57e-2)" "unprognostic (2.14e-1)" "potential prognostic favorable (1.66e-5)" "unprognostic (7.62e-2)" "unprognostic (9.45e-2)" "unprognostic (2.00e-2)" "unprognostic (7.78e-2)" "unprognostic (1.85e-1)" "unprognostic (1.65e-3)" "unprognostic (2.23e-2)" "potential prognostic unfavorable (8.71e-4)" "unprognostic (9.79e-2)" "unprognostic (3.89e-1)" "unprognostic (1.03e-1)" "unprognostic (3.91e-2)" DNASE1L3 "DNAS1L3, LSD" ENSG00000163687 "Deoxyribonuclease 1 like 3" Q13609 3 58192257-58214697 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Necrosis" "Endonuclease, Hydrolase, Nuclease" "Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "liver: 253.4;lymphoid tissue: 247.9" "Cell type enhanced" "Detected in many" "cDC: 130.0;Esophageal basal cells: 71.9;Esophageal suprabasal cells: 98.2;Hepatic stellate cells: 116.2;Kupffer cells: 60.5;Lymphatic endothelial cells: 77.4;Macrophages: 45.1;pDCs: 306.6;Suprabasal keratinocytes: 114.4;Vascular endothelial cells: 134.9" "Cell type enhanced" "Detected in some" "cerebellar inhibitory: 2.8;endothelial cell: 4.3;fibroblast: 10.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 10 "plasmacytoid DC: 426.2" "Lineage enriched" "Detected in many" 20 "dendritic cells: 426.2" "Cancer enhanced" "Detected in some" "Leukemia: 3.1;lymphoma: 3.5;Rhabdoid: 4.8" "Adrenal gland - Endothelial cells, Liver - Sinusoid Endothelial cells, Minor Salivary Gland - Minor salivary gland basal cells" "Not detected" "Not detected" "Region enhanced" "Detected in single" "spinal cord: 1.0" HPA019955 Approved "Secreted to blood" Enzyme NA NA 5700000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 2 "HPA019955: " "unprognostic (1.01e-1)" "unprognostic (2.66e-2)" "unprognostic (2.59e-2)" "unprognostic (1.94e-2)" "unprognostic (7.52e-3)" "unprognostic (6.38e-2)" "unprognostic (2.59e-2)" "unprognostic (2.06e-3)" "validated prognostic favorable (3.77e-10)" "validated prognostic favorable (1.34e-4)" "unprognostic (1.72e-3)" "validated prognostic favorable (4.43e-7)" "validated prognostic favorable (2.02e-5)" "potential prognostic favorable (2.56e-6)" "unprognostic (2.59e-2)" "unprognostic (5.01e-2)" "unprognostic (5.99e-1)" "unprognostic (3.84e-3)" "unprognostic (5.85e-3)" "unprognostic (1.26e-1)" "unprognostic (2.13e-2)" "unprognostic (7.81e-2)" "unprognostic (2.05e-1)" "unprognostic (1.42e-1)" "unprognostic (2.60e-1)" "unprognostic (1.61e-1)" DNASE2 "DNL, DNL2" ENSG00000105612 "Deoxyribonuclease 2, lysosomal" O00115 19 12875209-12881595 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Apoptosis "Developmental protein, Endonuclease, Hydrolase, Nuclease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 131.9;Hofbauer cells: 210.7;Kupffer cells: 109.7" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 28.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Kidney - Fibroblasts, Lung - Macrophages, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066185 Enhanced "Intracellular and membrane" "Developmental protein" NA NA 130000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 70: Non-specific - Protein processing" "Cluster 39: Astrocytes - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 1 "HPA066185: " "unprognostic (8.53e-2)" "unprognostic (8.62e-2)" "unprognostic (1.30e-2)" "unprognostic (1.85e-1)" "unprognostic (8.18e-2)" "unprognostic (5.07e-2)" "unprognostic (3.08e-2)" "unprognostic (7.15e-3)" "unprognostic (3.33e-1)" "unprognostic (3.10e-3)" "potential prognostic favorable (5.42e-4)" "unprognostic (6.95e-2)" "unprognostic (1.26e-1)" "unprognostic (2.02e-1)" "unprognostic (2.80e-1)" "unprognostic (2.25e-2)" "unprognostic (1.79e-1)" "unprognostic (2.54e-2)" "unprognostic (6.48e-2)" "unprognostic (2.93e-2)" "unprognostic (1.50e-1)" "unprognostic (7.03e-2)" "unprognostic (3.43e-1)" "unprognostic (2.20e-1)" "unprognostic (7.06e-2)" "unprognostic (2.26e-3)" "unprognostic (5.76e-2)" "unprognostic (9.03e-2)" "unprognostic (3.98e-2)" "unprognostic (2.91e-1)" "unprognostic (1.01e-2)" DNASE2B DLAD ENSG00000137976 "Deoxyribonuclease 2 beta" Q8WZ79 1 84398484-84415018 "Enzymes, Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 25 "salivary gland: 160.3" "Group enriched" "Detected in some" 6 "Lacrimal acinar cells: 33.5;Salivary acinar cells: 98.4;Salivary myoepithelial cells: 52.3" "Low cell type specificity" "Detected in some" "Group enriched" "Detected in some" 4 "Prostate Adenocarcinoma (TCGA): 19.4;Skin Cutaneous Melanoma (TCGA): 5.7" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "head and neck cancer: 8.4;prostate cancer: 4.1" "Lung - Macrophages, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Intracellular and membrane" Enzyme NA NA "Cluster 82: Salivary gland - Secretion" "Cluster 30: White matter - Myelination" "Cluster 65: Non-specific - Unknown function" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 3 "unprognostic (2.13e-1)" "unprognostic (4.43e-2)" "unprognostic (7.87e-2)" "unprognostic (7.44e-3)" "unprognostic (6.46e-2)" "unprognostic (1.66e-2)" "unprognostic (1.28e-1)" "unprognostic (1.96e-1)" "unprognostic (6.16e-2)" DND1 "MGC34750, RBMS4" ENSG00000256453 "DND microRNA-mediated repression inhibitor 1" Q8IYX4 5 140670794-140673576 "Predicted intracellular proteins" "Developmental protein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 3.3;testis: 11.6" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 10.8;Differentiating spermatogonia: 25.4;Early primary spermatocytes: 10.5;Early spermatids: 46.8;Epicardial cells: 13.6;Oocytes: 152.0;Undifferentiated spermatogonia: 40.0" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in some" 4 "Testicular Germ Cell Tumor (TCGA): 27.8" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA038443, HPA059723" Supported "Nucleoplasm,Focal adhesion sites,Cytosol" NA NA "Cluster 67: Testis - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 56: Non-specific - Sensory perception" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 5 Nucleoplasm "Focal adhesion sites, Cytosol" "HPA038443: , HPA059723: " "unprognostic (1.75e-1)" "unprognostic (1.37e-3)" "unprognostic (9.12e-2)" "unprognostic (1.77e-2)" "potential prognostic unfavorable (3.60e-4)" "unprognostic (1.59e-2)" "unprognostic (2.41e-1)" DNER "bet, UNQ26" ENSG00000187957 "Delta/notch like EGF repeat containing" Q8NFT8 2 229357629-229714555 "Cancer-related genes, Predicted membrane proteins" "Notch signaling pathway" "Activator, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 67.9;brain: 121.9;choroid plexus: 144.6" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 273.2;Bergmann glia: 238.8;Brain inhibitory neurons: 265.9;Choroid plexus epithelial cells: 571.9;Corticotrophs: 567.5;Ependymal cells: 244.8;Lactotrophs: 234.7;Oligodendrocyte progenitor cells: 644.2;Oligodendrocytes: 348.6;Other brain neurons: 321.6;Parietal cells: 194.5;Retinal amacrine cells: 371.3;Retinal ganglion cells: 197.0;Salivary acinar cells: 388.6;Somatotrophs: 195.9;Thyrotrophs: 202.4" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 24 "Glioblastoma Multiforme (TCGA): 142.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 106.9" "Adrenal gland - Adrenal cortex cells, Colon - Colon enteroendocrine cells, Lung - Respiratory ciliated cells, Pituitary gland - Corticotropes, Skin - Eccrine sweat gland cells, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017320 Enhanced NA NA 1300000 "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 45: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 109: Neurons - Neuronal signaling" 1 "HPA017320: " "unprognostic (8.32e-3)" "unprognostic (1.41e-2)" "unprognostic (4.12e-2)" "unprognostic (1.01e-3)" "unprognostic (1.42e-1)" "unprognostic (3.09e-1)" "unprognostic (2.25e-2)" "unprognostic (2.69e-1)" "potential prognostic unfavorable (7.18e-5)" "unprognostic (4.71e-3)" "unprognostic (1.62e-2)" "potential prognostic unfavorable (3.42e-4)" "potential prognostic unfavorable (5.73e-6)" "unprognostic (1.40e-1)" "unprognostic (2.33e-1)" "unprognostic (2.62e-1)" "unprognostic (1.78e-1)" "unprognostic (1.85e-1)" "unprognostic (2.14e-3)" "unprognostic (1.17e-1)" "unprognostic (8.52e-2)" "unprognostic (2.14e-2)" "unprognostic (9.19e-2)" "unprognostic (1.02e-2)" DNHD1 "C11orf47, CCDC35, DHCD1, DKFZp686J0796, DNHD1L, FLJ32752, FLJ35709, FLJ46184" ENSG00000179532 "Dynein heavy chain domain 1" Q96M86 11 6497260-6593758 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 165.1;Cardiomyocytes: 300.4;Epicardial cells: 227.4;Myonuclei: 150.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in many" "HPA039698, HPA040267" Uncertain Supported "Mid piece,Annulus" NA No "Cluster 67: Testis - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 1 "Mid piece" Annulus "HPA039698: , HPA040267: " "unprognostic (1.05e-2)" "unprognostic (2.70e-1)" "unprognostic (8.04e-3)" "unprognostic (2.22e-1)" "unprognostic (2.57e-1)" "unprognostic (1.02e-1)" "unprognostic (1.42e-2)" "potential prognostic unfavorable (5.65e-5)" "unprognostic (2.19e-1)" "unprognostic (3.06e-1)" "unprognostic (1.09e-2)" "unprognostic (2.02e-1)" "unprognostic (3.64e-1)" "unprognostic (9.11e-2)" "unprognostic (3.38e-2)" "unprognostic (4.02e-2)" "unprognostic (1.63e-2)" "unprognostic (2.10e-2)" "unprognostic (1.82e-1)" "unprognostic (2.66e-1)" "unprognostic (2.85e-1)" DNLZ "bA413M3.2, C9orf151, HEP, RP11-413M3.2, TIMM15, ZIM17" ENSG00000213221 "DNL-type zinc finger" Q5SXM8 9 136359480-136363744 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 10.6;Epididymal clear cells: 6.1;Epididymal principal cells: 11.8;Fallopian secretory cells: 4.8;Respiratory ionocytes: 5.1" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062738 Supported Nucleoplasm,Mitochondria NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 24: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 15: Non-specific - Protein processing" 2 Mitochondria Nucleoplasm "HPA062738: " "unprognostic (1.76e-2)" "unprognostic (8.46e-2)" "unprognostic (1.06e-1)" "unprognostic (8.94e-3)" "unprognostic (5.93e-2)" "unprognostic (3.71e-2)" "unprognostic (7.06e-2)" "unprognostic (1.19e-1)" "unprognostic (1.44e-1)" "unprognostic (7.06e-2)" "unprognostic (2.49e-1)" "unprognostic (1.92e-1)" "unprognostic (3.64e-2)" "unprognostic (9.95e-3)" "unprognostic (2.28e-2)" "unprognostic (6.92e-2)" "unprognostic (9.61e-2)" "unprognostic (1.45e-1)" "unprognostic (2.98e-2)" "unprognostic (3.87e-3)" "unprognostic (6.64e-2)" "unprognostic (2.88e-2)" "unprognostic (8.81e-2)" "unprognostic (9.07e-2)" "unprognostic (1.17e-1)" "unprognostic (1.30e-1)" "unprognostic (6.56e-2)" "unprognostic (1.47e-1)" DNM1 DNM ENSG00000106976 "Dynamin 1" Q05193 9 128191655-128255248 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Endocytosis "Hydrolase, Motor protein" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "brain: 353.4" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 310.3;Brain inhibitory neurons: 220.5;Cone photoreceptor cells: 211.2;Fibro-adipogenic progenitors: 195.7;Other brain neurons: 179.4;Proximal tubule cells: 141.6;Retinal amacrine cells: 239.5;Retinal bipolar cells: 200.0;Retinal ganglion cells: 394.0;Rod photoreceptor cells: 199.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Renal Papillary Cell Carcinoma (TCGA): 46.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Lung - Fibroblasts_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005920, HPA049910" Enhanced NA NA 79000 "Cluster 10: Brain - Synaptic signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 42 "CAB005920: , HPA049910: " "unprognostic (2.12e-1)" "unprognostic (4.73e-3)" "unprognostic (1.59e-1)" "unprognostic (1.01e-1)" "unprognostic (1.88e-3)" "unprognostic (1.16e-1)" "unprognostic (4.53e-2)" "unprognostic (8.41e-3)" "unprognostic (6.77e-2)" "unprognostic (7.01e-3)" "unprognostic (1.88e-1)" "unprognostic (2.55e-1)" "unprognostic (1.46e-1)" "potential prognostic unfavorable (3.31e-5)" "unprognostic (9.31e-2)" "unprognostic (4.14e-2)" "unprognostic (5.20e-2)" "unprognostic (1.48e-1)" "unprognostic (8.17e-2)" "unprognostic (4.09e-2)" "unprognostic (2.17e-1)" "unprognostic (5.21e-3)" "unprognostic (1.18e-2)" "unprognostic (1.71e-1)" "unprognostic (8.19e-2)" "unprognostic (6.29e-2)" "unprognostic (5.57e-2)" "unprognostic (1.76e-1)" "unprognostic (1.01e-1)" "unprognostic (1.22e-2)" "unprognostic (1.50e-2)" DNM1L "DRP1, DVLP, DYMPLE, HDYNIV, VPS1" ENSG00000087470 "Dynamin 1 like" O00429 12 32679200-32745650 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Biological rhythms, Endocytosis, Necrosis" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009952, HPA039324" Approved Supported Vesicles,Cytosol NA NA 2500000 "Cluster 13: Non-specific - Mitochondria" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 38: Non-specific - Transcription" "Cluster 69: Urothelial cells - Basic cellular functions" 41 Cytosol Vesicles "CAB009952: , HPA039324: " "unprognostic (2.32e-1)" "unprognostic (2.10e-2)" "unprognostic (3.18e-1)" "unprognostic (2.52e-1)" "unprognostic (7.63e-2)" "unprognostic (1.76e-1)" "unprognostic (2.25e-1)" "unprognostic (1.69e-2)" "unprognostic (1.49e-1)" "potential prognostic unfavorable (2.06e-5)" "unprognostic (3.84e-2)" "unprognostic (1.15e-1)" "unprognostic (3.69e-2)" "potential prognostic unfavorable (1.42e-4)" "unprognostic (3.73e-2)" "unprognostic (3.37e-3)" "unprognostic (1.02e-1)" "unprognostic (1.30e-1)" "unprognostic (3.51e-1)" "unprognostic (1.44e-1)" "unprognostic (3.97e-1)" "unprognostic (3.41e-1)" "unprognostic (4.44e-3)" "unprognostic (1.06e-1)" "unprognostic (3.30e-2)" "unprognostic (9.74e-2)" "unprognostic (2.61e-2)" "unprognostic (2.23e-1)" "unprognostic (5.66e-1)" "unprognostic (6.20e-2)" "unprognostic (1.11e-1)" DNM2 "CMT2M, CMTDI1, CMTDIB, DI-CMTB, DYN2, DYNII" ENSG00000079805 "Dynamin 2" P50570 19 10718055-10833488 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Endocytosis, Phagocytosis" "Hydrolase, Motor protein" "Cancer-related genes, Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 569.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054246 Supported Supported "Golgi apparatus,Cytosol" NA NA 150000 "Cluster 29: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 23: Non-specific - Transcription" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 65 "Golgi apparatus, Cytosol" "HPA054246: " "unprognostic (3.08e-2)" "unprognostic (1.48e-1)" "unprognostic (1.26e-2)" "unprognostic (1.60e-1)" "unprognostic (1.74e-1)" "unprognostic (3.58e-2)" "unprognostic (2.26e-1)" "unprognostic (7.90e-2)" "potential prognostic favorable (5.81e-4)" "unprognostic (4.66e-3)" "potential prognostic favorable (1.55e-4)" "unprognostic (1.27e-1)" "unprognostic (2.76e-1)" "unprognostic (3.43e-3)" "unprognostic (2.15e-2)" "unprognostic (4.69e-1)" "unprognostic (6.57e-2)" "unprognostic (1.80e-1)" "unprognostic (1.07e-1)" "unprognostic (1.62e-1)" "unprognostic (2.35e-1)" "unprognostic (1.04e-2)" "unprognostic (9.77e-2)" "unprognostic (3.82e-2)" "unprognostic (7.23e-2)" "unprognostic (1.41e-1)" "unprognostic (1.56e-1)" "unprognostic (5.63e-2)" "unprognostic (5.38e-2)" "unprognostic (1.71e-1)" "unprognostic (8.70e-2)" DNM3 KIAA0820 ENSG00000197959 "Dynamin 3" Q9UQ16 1 171817887-172418466 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Endocytosis "Hydrolase, Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 39.9" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 531.3;Brain excitatory neurons: 807.0;Brain inhibitory neurons: 732.1;Choroid plexus epithelial cells: 687.5;Lactotrophs: 833.8;Oligodendrocyte progenitor cells: 1327.0;Oligodendrocytes: 2116.5;Other brain neurons: 598.4;Platelets: 764.0;Thyrotrophs: 569.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 15.4" "Adipose subcutaneous - Endothelial cells, Colon - Enteric glia cells, Testis - Early spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064121 Uncertain "Golgi apparatus" NA NA 43000 "Cluster 35: Neutrophils - Protein binding" "Cluster 27: Cerebellum - Synaptic function" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 80: Oligodendrocytes - Myelination" 12 "Golgi apparatus" "HPA064121: " "unprognostic (2.54e-1)" "unprognostic (3.92e-2)" "unprognostic (2.03e-2)" "unprognostic (9.31e-3)" "unprognostic (9.79e-2)" "unprognostic (1.87e-2)" "unprognostic (1.28e-1)" "potential prognostic favorable (2.20e-5)" "unprognostic (7.03e-2)" "potential prognostic favorable (4.75e-4)" "potential prognostic favorable (4.01e-5)" "unprognostic (2.35e-3)" "unprognostic (1.37e-2)" "unprognostic (4.98e-2)" "unprognostic (3.68e-1)" "unprognostic (1.75e-2)" "unprognostic (7.73e-2)" "unprognostic (9.37e-3)" "unprognostic (5.42e-3)" "unprognostic (3.93e-1)" "unprognostic (3.39e-1)" "unprognostic (1.51e-1)" "unprognostic (1.07e-1)" "unprognostic (7.71e-2)" "unprognostic (5.93e-2)" "unprognostic (6.85e-3)" "unprognostic (1.01e-1)" "unprognostic (3.14e-1)" "unprognostic (1.19e-1)" DNMBP "ARHGEF36, KIAA1010, Tuba" ENSG00000107554 "Dynamin binding protein" Q6XZF7 10 99875577-100009947 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Cataract, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 278.4;Ocular epithelial cells: 416.6;Urothelial cells: 493.9" "Cell type enhanced" "Detected in all" "fibroblast: 159.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037878, HPA058216" Uncertain Approved "Nucleoplasm,Nucleoli,Nuclear bodies,Golgi apparatus,Cytosol" Yes No "Cluster 14: Non-specific - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 100: Stratified epithelial cells - Barrier functions" 24 "Nucleoli, Golgi apparatus, Cytosol" "Nucleoplasm, Nuclear bodies" "HPA037878: , HPA058216: " "unprognostic (1.49e-2)" "unprognostic (2.09e-1)" "unprognostic (2.40e-2)" "unprognostic (3.49e-1)" "unprognostic (1.95e-1)" "unprognostic (2.46e-1)" "unprognostic (2.77e-3)" "unprognostic (1.58e-2)" "unprognostic (1.41e-1)" "unprognostic (2.00e-1)" "validated prognostic favorable (1.61e-5)" "validated prognostic favorable (3.17e-4)" "unprognostic (1.88e-2)" "unprognostic (1.12e-1)" "unprognostic (1.22e-2)" "unprognostic (2.74e-2)" "unprognostic (1.57e-2)" "unprognostic (7.05e-2)" "unprognostic (8.72e-2)" "unprognostic (4.06e-2)" "unprognostic (7.11e-2)" "unprognostic (2.72e-3)" "unprognostic (3.60e-1)" "unprognostic (5.21e-2)" "unprognostic (3.02e-2)" "unprognostic (2.58e-2)" "unprognostic (1.10e-1)" "unprognostic (2.24e-1)" "unprognostic (4.28e-2)" "unprognostic (2.21e-2)" "potential prognostic favorable (2.12e-4)" DNMT1 "CXXC9, DNMT, MCMT" ENSG00000130816 "DNA methyltransferase 1" P26358 19 10133342-10231286 "Disease related genes, Enzymes, Essential proteins, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Chromatin regulator, DNA-binding, Methyltransferase, Repressor, Transferase" "Deafness, Disease variant, FDA approved drug targets, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 570.4;Early primary spermatocytes: 285.0;Erythrocyte progenitors: 317.5;Megakaryocyte progenitors: 240.7;Migrating cytotrophoblasts: 391.2;Monocyte progenitors: 256.8;Syncytiotrophoblasts: 382.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002694, CAB005876" Enhanced Supported Nucleoplasm NA Yes "Cluster 30: Non-specific - DNA binding" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 6: Non-specific - Immune response" "Cluster 23: Non-specific - Transcription" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 85 Nucleoplasm "CAB005876: , HPA002694: " "unprognostic (3.94e-3)" "unprognostic (2.04e-1)" "unprognostic (1.06e-1)" "unprognostic (2.78e-1)" "unprognostic (1.87e-1)" "unprognostic (9.37e-2)" "unprognostic (2.28e-1)" "unprognostic (5.79e-2)" "unprognostic (4.99e-3)" "unprognostic (1.53e-1)" "potential prognostic favorable (9.36e-4)" "unprognostic (1.05e-1)" "unprognostic (8.29e-2)" "potential prognostic unfavorable (5.33e-4)" "unprognostic (4.58e-3)" "unprognostic (5.90e-3)" "unprognostic (1.78e-3)" "unprognostic (8.93e-2)" "unprognostic (1.78e-2)" "unprognostic (2.30e-1)" "unprognostic (1.65e-1)" "unprognostic (2.76e-3)" "unprognostic (9.00e-3)" "unprognostic (6.39e-3)" "unprognostic (2.54e-2)" "unprognostic (2.99e-2)" "unprognostic (5.50e-2)" "unprognostic (2.26e-2)" "unprognostic (2.32e-1)" "unprognostic (8.67e-2)" "unprognostic (1.24e-1)" DNMT3A ENSG00000119772 "DNA methyltransferase 3 alpha" Q9Y6K1 2 25227855-25342590 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Chromatin regulator, DNA-binding, Methyltransferase, Repressor, Transferase" "Cancer-related genes, Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gonadotrophs: 233.8;Myonuclei: 261.5;Rod photoreceptor cells: 254.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009469, HPA026588" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 7: Non-specific - Transcription" 57 Nucleoplasm Vesicles "CAB009469: , HPA026588: " "potential prognostic favorable (9.16e-4)" "unprognostic (1.30e-1)" "unprognostic (2.86e-1)" "unprognostic (2.27e-1)" "unprognostic (6.48e-2)" "unprognostic (1.06e-1)" "unprognostic (8.92e-2)" "unprognostic (1.87e-1)" "unprognostic (7.16e-2)" "unprognostic (2.32e-2)" "unprognostic (8.53e-2)" "unprognostic (3.65e-2)" "unprognostic (3.73e-2)" "validated prognostic unfavorable (4.36e-6)" "validated prognostic unfavorable (7.61e-4)" "unprognostic (2.62e-2)" "potential prognostic unfavorable (6.96e-4)" "unprognostic (1.50e-1)" "unprognostic (1.81e-2)" "unprognostic (1.18e-1)" "unprognostic (1.47e-1)" "unprognostic (2.73e-1)" "unprognostic (1.44e-2)" "unprognostic (2.00e-2)" "unprognostic (1.79e-1)" "unprognostic (8.88e-2)" "unprognostic (2.89e-1)" "unprognostic (3.80e-2)" "unprognostic (1.60e-1)" "unprognostic (1.69e-1)" "unprognostic (1.52e-1)" DNMT3B ENSG00000088305 "DNA methyltransferase 3 beta" Q9UBC3 20 32762385-32809359 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Activator, DNA-binding, Methyltransferase, Repressor, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 5.8;testis: 5.7" "Cell type enhanced" "Detected in many" "Hematopoietic stem cells: 46.6;Megakaryocyte progenitors: 55.9;Megakaryocyte-Erythroid progenitors: 26.9;Migrating cytotrophoblasts: 18.4;Pancreatic acinar cells: 21.3;Retinal amacrine cells: 19.2;Sertoli cells: 61.9;Thymocytes: 18.6" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in many" 18 "Testicular Germ Cell Tumor (TCGA): 242.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in all" 6 "testis cancer: 122.2" "Skeletal muscle - Fibroblasts, Stomach - Mitotic cells (Stomach)" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA001595, HPA001803, CAB069896" Enhanced Supported Nucleoplasm NA Yes "Cluster 21: Testis - Mixed function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 34: Testis cancer - Unknown function" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 40 Nucleoplasm "CAB069896: , HPA001595: , HPA001803: " "unprognostic (1.98e-1)" "unprognostic (1.67e-2)" "unprognostic (5.85e-2)" "unprognostic (3.88e-3)" "unprognostic (2.49e-2)" "unprognostic (3.86e-2)" "unprognostic (4.01e-1)" "unprognostic (1.20e-1)" "unprognostic (1.92e-1)" "unprognostic (2.19e-1)" "potential prognostic unfavorable (4.16e-6)" "unprognostic (1.20e-3)" "unprognostic (2.80e-2)" "unprognostic (5.04e-2)" "unprognostic (7.76e-3)" "unprognostic (6.66e-2)" "unprognostic (5.99e-2)" "unprognostic (4.01e-3)" "unprognostic (1.89e-1)" "unprognostic (2.67e-1)" "unprognostic (3.62e-2)" "potential prognostic unfavorable (5.87e-4)" "unprognostic (1.41e-2)" "unprognostic (6.30e-2)" "unprognostic (1.00e-2)" "unprognostic (3.63e-1)" "unprognostic (1.35e-1)" "unprognostic (2.19e-1)" "unprognostic (7.90e-2)" DNMT3L MGC1090 ENSG00000142182 "DNA methyltransferase 3 like" Q9UJW3 21 44246339-44262216 "Metabolic proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "liver: 1.8" "Group enriched" "Detected in some" 4 "Epicardial cells: 20.5;Hepatocytes: 22.1" "Cell type enhanced" "Detected in single" "vascular associated smooth muscle cell: 1.5" "Cancer enriched" "Detected in some" 45 "Testicular Germ Cell Tumor (TCGA): 101.9" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "testis cancer: 5.3" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA055234, HPA066780" Approved Approved "Nuclear speckles" NA NA "Cluster 16: Liver & Kidney - Metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 34: Testis cancer - Unknown function" "Cluster 93: Hepatocytes - Bile production & excretion" 11 "Nuclear speckles" "HPA055234: , HPA066780: " "unprognostic (2.18e-2)" "unprognostic (5.98e-2)" DNPEP "ASPEP, DAP" ENSG00000123992 "Aspartyl aminopeptidase" Q9ULA0 2 219372043-219400022 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 466.7;Enterocytes: 205.5;Late spermatids: 716.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036398, HPA044860" Enhanced Supported Cytosol NA NA 360000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 77: Intestine - Digestion" "Cluster 19: Astrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 19 Cytosol "HPA036398: , HPA044860: " "unprognostic (7.09e-3)" "unprognostic (6.41e-2)" "unprognostic (1.12e-1)" "unprognostic (1.78e-1)" "unprognostic (1.60e-1)" "unprognostic (2.92e-1)" "unprognostic (8.05e-2)" "unprognostic (1.61e-2)" "unprognostic (3.31e-1)" "unprognostic (7.79e-2)" "potential prognostic favorable (2.51e-6)" "unprognostic (1.29e-1)" "unprognostic (1.77e-2)" "potential prognostic unfavorable (2.84e-4)" "unprognostic (1.82e-2)" "unprognostic (1.29e-3)" "unprognostic (7.67e-3)" "unprognostic (5.25e-2)" "unprognostic (1.61e-2)" "unprognostic (9.41e-2)" "unprognostic (1.76e-3)" "unprognostic (8.30e-3)" "unprognostic (2.41e-1)" "unprognostic (1.25e-1)" "unprognostic (7.06e-2)" "unprognostic (1.70e-1)" "unprognostic (2.44e-1)" "unprognostic (2.49e-2)" "unprognostic (2.79e-2)" "unprognostic (1.76e-1)" "unprognostic (8.32e-2)" DNPH1 "C6orf108, dJ330M21.3, rcl" ENSG00000112667 "2'-deoxynucleoside 5'-phosphate N-hydrolase 1" O43598 6 43225629-43229481 "Predicted intracellular proteins" "Nucleotide metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enteric transient amplifying cells: 289.4;Enterocytes: 713.3;Epididymal efferent duct absorptive cells: 371.1;Epididymal efferent duct ciliated cells: 410.5;Fallopian tube ciliated cells: 391.5;Hepatocytes: 270.4;Hofbauer cells: 432.6;Respiratory ciliated cells: 295.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029675, HPA029676" Enhanced Approved Nucleoplasm,Cytosol No No 290000 "Cluster 33: Non-specific - ATP binding" "Cluster 72: Kidney - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 1: Enterocytes - Absorption and Digestion" 5 Nucleoplasm Cytosol "HPA029675: , HPA029676: " "unprognostic (7.89e-2)" "unprognostic (1.99e-2)" "unprognostic (2.92e-1)" "unprognostic (5.26e-2)" "unprognostic (3.49e-2)" "unprognostic (1.74e-1)" "unprognostic (2.03e-1)" "unprognostic (5.86e-2)" "unprognostic (6.35e-2)" "unprognostic (4.58e-2)" "unprognostic (1.18e-1)" "unprognostic (2.51e-2)" "unprognostic (1.75e-1)" "unprognostic (1.86e-1)" "unprognostic (1.39e-1)" "unprognostic (1.43e-2)" "unprognostic (2.98e-1)" "unprognostic (1.91e-2)" "unprognostic (4.05e-2)" "unprognostic (7.41e-2)" "unprognostic (3.29e-3)" "unprognostic (4.05e-1)" "unprognostic (9.85e-2)" "unprognostic (1.25e-2)" "unprognostic (8.61e-2)" "unprognostic (8.53e-2)" "unprognostic (2.02e-1)" "unprognostic (2.44e-3)" "unprognostic (1.02e-2)" DNTT TDT ENSG00000107447 "DNA nucleotidylexotransferase" P04053 10 96304409-96338564 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Terminal addition" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "lymphoid tissue: 306.4" "Cell type enriched" "Detected in some" 8 "Thymocytes: 160.1" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "Kidney Chromophobe (TCGA): 2.3" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "naive CD4 T-cell: 1.3" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in some" 6 "Leukemia: 225.7" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA036532, HPA044194" Supported Nucleoplasm,Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 80: Thymus - Adaptive immune response" "Cluster 6: Leukemia - Signal transduction" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 7 Nucleoplasm Cytosol "HPA036532: , HPA044194: " "unprognostic (3.86e-2)" DNTTIP1 "C20orf167, dJ447F3.4, Tdif1" ENSG00000101457 "Deoxynucleotidyltransferase terminal interacting protein 1" Q9H147 20 45791954-45811427 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 160.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 125.6" "Group enriched" "Detected in all" 6 "dendritic cells: 43.4;granulocytes: 125.6;monocytes: 51.0" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Spleen - Neutrophils_2, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045496 Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 21: Neutrophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 24: Neutrophils - Innate immunity signal integration" 35 "Nucleoli, Nucleoli rim, Mitotic chromosome" Nucleoplasm "HPA045496: " "unprognostic (1.17e-1)" "unprognostic (2.80e-1)" "unprognostic (2.29e-1)" "unprognostic (3.80e-1)" "unprognostic (4.45e-2)" "unprognostic (2.12e-1)" "unprognostic (7.43e-2)" "unprognostic (3.45e-1)" "unprognostic (1.07e-2)" "unprognostic (2.08e-1)" "validated prognostic unfavorable (4.26e-8)" "validated prognostic unfavorable (5.82e-7)" "unprognostic (2.20e-1)" "validated prognostic unfavorable (8.76e-6)" "validated prognostic unfavorable (1.04e-4)" "unprognostic (5.29e-2)" "potential prognostic unfavorable (3.44e-4)" "unprognostic (6.74e-2)" "unprognostic (1.30e-1)" "unprognostic (2.97e-1)" "unprognostic (8.90e-2)" "unprognostic (1.43e-2)" "unprognostic (1.31e-2)" "unprognostic (5.38e-2)" "unprognostic (1.04e-1)" "unprognostic (9.92e-2)" "unprognostic (3.01e-1)" "unprognostic (3.64e-1)" "unprognostic (4.98e-1)" "unprognostic (5.89e-2)" "unprognostic (8.16e-2)" DNTTIP2 "ERBP, HSU15552, TdIF2" ENSG00000067334 "Deoxynucleotidyltransferase terminal interacting protein 2" Q5QJE6 1 93866284-93879918 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 41.3" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044502, HPA053707" Supported Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 21 "Nucleoli, Nucleoli rim" "Nucleoplasm, Mitotic chromosome" "HPA044502: , HPA053707: " "unprognostic (2.02e-1)" "unprognostic (2.90e-1)" "unprognostic (8.38e-2)" "unprognostic (2.12e-1)" "unprognostic (2.38e-2)" "unprognostic (2.62e-2)" "unprognostic (2.91e-2)" "unprognostic (4.45e-1)" "unprognostic (3.82e-2)" "potential prognostic unfavorable (9.57e-6)" "unprognostic (3.01e-3)" "unprognostic (1.21e-3)" "unprognostic (1.57e-3)" "potential prognostic unfavorable (1.76e-7)" "unprognostic (2.66e-2)" "potential prognostic unfavorable (8.37e-4)" "unprognostic (7.42e-3)" "unprognostic (3.34e-2)" "unprognostic (5.54e-2)" "unprognostic (5.99e-2)" "unprognostic (2.88e-1)" "unprognostic (3.09e-2)" "unprognostic (1.91e-2)" "unprognostic (2.23e-1)" "unprognostic (9.66e-3)" "unprognostic (9.84e-3)" "unprognostic (1.54e-2)" "unprognostic (2.48e-1)" "unprognostic (1.63e-1)" "unprognostic (1.30e-1)" "unprognostic (3.41e-1)" DOC2A ENSG00000149927 "Double C2 domain alpha" Q14183 16 30005514-30023270 "Predicted intracellular proteins" Exocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 91.7;testis: 35.5" "Group enriched" "Detected in many" 5 "Early spermatids: 363.6;Ependymal cells: 226.0;Late primary spermatocytes: 130.5;Late spermatids: 407.6;Respiratory ciliated cells: 146.1" "Cell type enhanced" "Detected in all" "ependymal cell: 222.1" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 20.6;Kidney Renal Papillary Cell Carcinoma (TCGA): 20.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA065676 Approved "Nucleoplasm,Nucleoli,Cell Junctions" NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" 12 "Cell Junctions" "Nucleoplasm, Nucleoli" "HPA065676: " "unprognostic (3.86e-2)" "unprognostic (2.49e-2)" "unprognostic (4.58e-2)" "unprognostic (3.75e-2)" "unprognostic (2.80e-3)" "unprognostic (1.51e-1)" "unprognostic (1.70e-2)" "unprognostic (2.57e-1)" "unprognostic (1.93e-1)" "unprognostic (6.02e-2)" "unprognostic (2.61e-2)" "unprognostic (1.75e-2)" "unprognostic (1.55e-1)" "unprognostic (5.15e-2)" "unprognostic (4.26e-2)" "unprognostic (3.14e-2)" "unprognostic (7.71e-2)" "unprognostic (5.73e-3)" "unprognostic (1.01e-1)" "unprognostic (3.44e-3)" "unprognostic (2.74e-2)" "unprognostic (3.07e-2)" "unprognostic (3.12e-2)" "unprognostic (2.13e-1)" "unprognostic (4.12e-2)" "unprognostic (4.47e-2)" "unprognostic (5.73e-2)" DOC2B DOC2BL ENSG00000272636 "Double C2 domain beta" Q14184 17 142789-181650 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 53.3;retina: 39.0" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 16.5;Brain inhibitory neurons: 12.7;Lymphatic endothelial cells: 8.4;Müller glia: 9.1;Oocytes: 27.6;Other brain neurons: 14.0;Papillary tip epithelial cells: 16.6;Renal collecting duct principal cells: 58.2;Renal connecting tubule cells: 45.6;Rod photoreceptor cells: 8.1" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 6.9;Stomach Adenocarcinoma (TCGA): 5.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Neuroblastoma: 19.1" "Breast - Endothelial cells, Heart muscle - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "basal ganglia: 71.0" HPA043168 Uncertain NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 29: Forebrain - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 1 "HPA043168: " "unprognostic (1.88e-2)" "unprognostic (6.51e-2)" "unprognostic (7.25e-2)" "unprognostic (5.75e-2)" "unprognostic (3.74e-1)" "unprognostic (2.64e-3)" "unprognostic (1.36e-1)" "unprognostic (1.36e-1)" "unprognostic (3.61e-1)" "unprognostic (8.60e-3)" "unprognostic (7.69e-2)" "unprognostic (2.82e-1)" "unprognostic (5.74e-2)" "unprognostic (2.54e-2)" DOCK1 "ced5, DOCK180" ENSG00000150760 "Dedicator of cytokinesis 1" Q14185 10 126905409-127452517 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Phagocytosis" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Loop of henle epithelial cells: 638.8;Oligodendrocytes: 600.2" "Cell type enhanced" "Detected in all" "endothelial cell: 661.0;oligodendrocyte: 748.6;oligodendrocyte precursor cell: 652.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Skeletal muscle - Endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004378, HPA048692, HPA070232" Approved Approved "Nucleoplasm,Nucleoli,Plasma membrane,Actin filaments,Focal adhesion sites,Cytosol" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 33 "Nucleoplasm, Cytosol" "Nucleoli, Plasma membrane, Actin filaments, Focal adhesion sites" "CAB004378: , HPA048692: , HPA070232: " "unprognostic (1.56e-2)" "unprognostic (1.68e-1)" "unprognostic (1.71e-1)" "potential prognostic unfavorable (4.76e-4)" "unprognostic (1.94e-1)" "unprognostic (3.53e-2)" "unprognostic (5.69e-2)" "unprognostic (2.66e-1)" "unprognostic (2.44e-1)" "unprognostic (1.72e-1)" "potential prognostic favorable (1.85e-6)" "unprognostic (8.77e-3)" "unprognostic (2.44e-1)" "unprognostic (2.52e-1)" "unprognostic (1.80e-2)" "unprognostic (9.53e-3)" "unprognostic (1.54e-1)" "unprognostic (1.39e-1)" "unprognostic (5.48e-3)" "unprognostic (9.20e-2)" "unprognostic (1.20e-2)" "unprognostic (3.19e-2)" "unprognostic (2.24e-2)" "unprognostic (4.06e-1)" "unprognostic (5.79e-3)" "unprognostic (7.60e-2)" "unprognostic (1.32e-1)" "unprognostic (1.09e-1)" "unprognostic (5.31e-2)" "unprognostic (9.29e-2)" "unprognostic (2.70e-1)" DOCK10 "KIAA0694, ZIZ3" ENSG00000135905 "Dedicator of cytokinesis 10" Q96BY6 2 224765090-225042468 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 34.2;lymphoid tissue: 35.0" "Cell type enhanced" "Detected in many" "cDC: 485.5;Innate lymphoid cells: 426.8;Mast cells: 714.0;Melanocytes: 475.7;Microglia: 1041.2;Monocyte progenitors: 502.3;monocytes: 443.5;NK-cells: 558.6;Oligodendrocyte progenitor cells: 646.3;Oligodendrocytes: 2022.0;Retinal horizontal cells: 809.4;T-cells: 649.9" "Cell type enhanced" "Detected in all" "oligodendrocyte: 2639.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Breast - T-cells, Lung - T-cells, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058106 Enhanced Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 11: White matter - Signal transduction" "Cluster 55: Lymphoma - Immune response" "Cluster 80: Oligodendrocytes - Myelination" 3 "Nucleoplasm, Cytosol" "HPA058106: " "unprognostic (3.28e-2)" "unprognostic (3.97e-2)" "unprognostic (1.49e-3)" "unprognostic (1.10e-1)" "unprognostic (2.18e-1)" "unprognostic (2.57e-1)" "unprognostic (1.13e-1)" "unprognostic (3.22e-2)" "unprognostic (3.53e-3)" "unprognostic (1.05e-1)" "unprognostic (2.15e-2)" "unprognostic (5.04e-2)" "unprognostic (1.86e-2)" "unprognostic (5.43e-2)" "unprognostic (1.38e-1)" "unprognostic (5.43e-2)" "unprognostic (3.99e-2)" "unprognostic (4.25e-1)" "unprognostic (2.42e-2)" "unprognostic (6.50e-2)" "unprognostic (7.28e-2)" "unprognostic (2.45e-3)" "unprognostic (5.67e-3)" "unprognostic (2.09e-1)" "unprognostic (6.15e-2)" "unprognostic (6.79e-2)" "unprognostic (1.84e-1)" "unprognostic (9.19e-2)" "unprognostic (1.10e-1)" "unprognostic (2.55e-1)" "unprognostic (2.66e-1)" DOCK11 "ACG, FLJ32122, FLJ43653, ZIZ2" ENSG00000147251 "Dedicator of cytokinesis 11" Q5JSL3 X 118495815-118686163 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 500.4;B-cells: 243.4;Hematopoietic stem cells: 216.4;Lactotrophs: 244.0;Macrophages: 241.9;Microglia: 287.3;Monocyte progenitors: 308.2;monocytes: 239.6;Neutrophil progenitors: 570.5;Neutrophils: 927.2" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 364.0;leukocyte: 383.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Leukemia: 23.9" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059695 Uncertain NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 21: Non-specific - Metabolism" "Cluster 49: HMC-1 - Innate immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 19 "HPA059695: " "unprognostic (1.32e-1)" "unprognostic (3.41e-2)" "unprognostic (9.04e-2)" "unprognostic (2.76e-2)" "unprognostic (5.04e-2)" "unprognostic (3.87e-2)" "unprognostic (4.52e-1)" "unprognostic (4.01e-3)" "unprognostic (8.90e-3)" "unprognostic (7.22e-2)" "unprognostic (8.34e-3)" "unprognostic (3.55e-1)" "unprognostic (1.62e-2)" "unprognostic (8.70e-2)" "unprognostic (7.84e-2)" "unprognostic (3.38e-2)" "unprognostic (1.13e-2)" "unprognostic (1.30e-1)" "unprognostic (9.75e-2)" "unprognostic (2.01e-2)" "unprognostic (5.96e-2)" "unprognostic (7.01e-2)" "unprognostic (1.91e-2)" "unprognostic (1.65e-1)" "unprognostic (3.43e-2)" "unprognostic (1.24e-1)" "unprognostic (7.65e-2)" "unprognostic (6.19e-3)" "unprognostic (2.83e-1)" "unprognostic (2.54e-2)" "unprognostic (1.10e-2)" DOCK2 KIAA0209 ENSG00000134516 "Dedicator of cytokinesis 2" Q92608 5 169637268-170083382 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 50.1;lung: 14.7;lymphoid tissue: 46.8" "Cell type enhanced" "Detected in many" "B-cells: 429.4;cDC: 364.7;Hematopoietic stem cells: 309.1;Kupffer cells: 362.8;Macrophages: 456.1;Microglia: 790.5;Monocyte progenitors: 644.4;monocytes: 642.9;Neutrophil progenitors: 1068.5;Neutrophils: 1627.5;NK-cells: 298.0;pDCs: 383.9;T-cells: 308.7;Thymocytes: 274.4" "Group enriched" "Detected in all" 15 "central nervous system macrophage: 1056.9;leukocyte: 741.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Kidney cancer: 30.7;Leukemia: 85.2;lymphoma: 97.1;Myeloma: 38.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Skeletal muscle - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA036469 Enhanced NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 38 "HPA036469: " "unprognostic (1.22e-1)" "unprognostic (1.24e-1)" "unprognostic (4.51e-3)" "unprognostic (1.24e-1)" "unprognostic (1.51e-1)" "unprognostic (1.97e-1)" "unprognostic (2.03e-1)" "unprognostic (1.11e-1)" "unprognostic (3.27e-3)" "unprognostic (1.36e-3)" "unprognostic (2.15e-1)" "unprognostic (3.13e-2)" "unprognostic (3.06e-2)" "unprognostic (3.12e-3)" "unprognostic (6.16e-2)" "unprognostic (6.14e-2)" "unprognostic (1.80e-1)" "unprognostic (2.71e-2)" "unprognostic (4.36e-1)" "unprognostic (9.07e-2)" "unprognostic (7.71e-3)" "unprognostic (2.48e-1)" "potential prognostic favorable (9.58e-4)" "unprognostic (4.10e-2)" "unprognostic (1.21e-1)" "unprognostic (7.89e-2)" "unprognostic (2.15e-2)" "unprognostic (2.42e-1)" DOCK3 "KIAA0299, MOCA, PBP" ENSG00000088538 "Dedicator of cytokinesis 3" Q8IZD9 3 50674927-51384198 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.5;retina: 9.3" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 888.8;Brain inhibitory neurons: 958.6;Choroid plexus epithelial cells: 664.3;Corticotrophs: 658.5;Gonadotrophs: 550.2;Lactotrophs: 508.7;Oligodendrocyte progenitor cells: 709.2;Oligodendrocytes: 963.7;Other brain neurons: 765.7;Retinal amacrine cells: 738.9;Retinal bipolar cells: 632.4;Retinal ganglion cells: 579.4;Retinal horizontal cells: 1139.9;Somatotrophs: 511.0;Thyrotrophs: 614.9" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Glioblastoma Multiforme (TCGA): 4.0;Thyroid Carcinoma (TCGA): 10.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037543, HPA037544" Enhanced Supported Enhanced Cytosol NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 53: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 109: Neurons - Neuronal signaling" 8 Cytosol "HPA037543: , HPA037544: " "unprognostic (2.04e-1)" "unprognostic (2.76e-1)" "unprognostic (2.68e-1)" "unprognostic (2.90e-3)" "unprognostic (7.85e-2)" "unprognostic (1.34e-1)" "unprognostic (2.98e-2)" DOCK4 "FLJ34238, KIAA0716" ENSG00000128512 "Dedicator of cytokinesis 4" Q8N1I0 7 111726110-112206407 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.0" "Cell type enhanced" "Detected in many" "Astrocytes: 1167.0;Macrophages: 1540.4;Microglia: 6744.0;monocytes: 1634.2;Neutrophils: 3894.0;Oligodendrocytes: 1144.3;Thyrotrophs: 1035.9" "Cell type enriched" "Detected in all" 4 "central nervous system macrophage: 8867.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Stomach - Endothelial cells, Thyroid gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071516 Approved "Nucleoli,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 36: Brain & Liver - Signaling" "Cluster 51: Neurons - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 9 "Nucleoli, Plasma membrane" "Golgi apparatus, Cytosol" "HPA071516: " "unprognostic (1.13e-1)" "unprognostic (2.18e-1)" "unprognostic (4.28e-1)" "unprognostic (2.56e-1)" "unprognostic (9.58e-2)" "unprognostic (7.74e-2)" "unprognostic (7.09e-2)" "unprognostic (1.14e-1)" "unprognostic (4.11e-2)" "potential prognostic unfavorable (2.16e-4)" "potential prognostic favorable (2.05e-6)" "unprognostic (2.44e-3)" "unprognostic (1.58e-1)" "unprognostic (1.71e-1)" "unprognostic (2.86e-1)" "unprognostic (6.74e-3)" "unprognostic (8.01e-2)" "unprognostic (2.48e-1)" "unprognostic (4.57e-3)" "unprognostic (1.37e-2)" "unprognostic (5.76e-3)" "unprognostic (1.11e-1)" "unprognostic (2.38e-2)" "unprognostic (1.99e-1)" "unprognostic (2.94e-2)" "unprognostic (7.93e-2)" "unprognostic (5.23e-2)" "unprognostic (1.82e-2)" "unprognostic (2.26e-1)" "unprognostic (8.66e-2)" "unprognostic (1.56e-1)" DOCK5 FLJ21034 ENSG00000147459 "Dedicator of cytokinesis 5" Q9H7D0 8 25184689-25418082 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 3294.7;Oligodendrocytes: 1106.9;Podocytes: 2267.7;Thyrotrophs: 748.4" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 920.8;oligodendrocyte: 1478.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 30.7" "Lineage enriched" "Detected in many" 4 "granulocytes: 30.7" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Colon - Enteric glia cells, Minor Salivary Gland - Minor salivary glandular cells, Spleen - Endothelial cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017719, HPA056837" Approved Enhanced Cytosol No No "Cluster 35: Neutrophils - Protein binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 24: Neutrophils - Innate immunity signal integration" 29 Cytosol "HPA017719: , HPA056837: " "unprognostic (1.24e-1)" "unprognostic (3.27e-1)" "unprognostic (4.79e-2)" "unprognostic (1.94e-2)" "unprognostic (1.99e-2)" "unprognostic (1.36e-1)" "unprognostic (1.14e-1)" "unprognostic (5.13e-2)" "unprognostic (1.14e-1)" "unprognostic (3.01e-3)" "unprognostic (9.02e-2)" "unprognostic (9.69e-2)" "unprognostic (3.82e-2)" "unprognostic (3.12e-2)" "unprognostic (1.05e-2)" "potential prognostic unfavorable (4.36e-4)" "unprognostic (2.29e-1)" "unprognostic (2.01e-2)" "unprognostic (1.46e-1)" "unprognostic (1.15e-1)" "unprognostic (8.82e-2)" "potential prognostic unfavorable (8.42e-4)" "unprognostic (1.35e-3)" "unprognostic (2.02e-1)" "unprognostic (5.84e-2)" "unprognostic (3.87e-2)" "unprognostic (4.65e-2)" "unprognostic (2.97e-1)" "unprognostic (2.55e-1)" "unprognostic (1.29e-3)" "unprognostic (3.13e-2)" DOCK6 "KIAA1395, ZIR1" ENSG00000130158 "Dedicator of cytokinesis 6" Q96HP0 19 11199295-11262524 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 120.5;Cardiomyocytes: 132.0;Lymphatic endothelial cells: 144.4;Pericytes: 97.1;Vascular endothelial cells: 135.4" "Cell type enhanced" "Detected in all" "endothelial cell: 161.7;fibroblast: 116.5;pericyte: 231.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells, Minor Salivary Gland - Endothelial cells, Pituitary gland - Endothelial cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049423, HPA049424" Approved Supported Cytosol NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 15 Cytosol "HPA049423: , HPA049424: " "unprognostic (1.79e-1)" "unprognostic (5.33e-2)" "unprognostic (6.43e-2)" "unprognostic (3.69e-3)" "unprognostic (3.26e-1)" "unprognostic (4.08e-1)" "unprognostic (8.05e-2)" "unprognostic (1.14e-3)" "unprognostic (2.21e-2)" "unprognostic (5.33e-2)" "validated prognostic favorable (5.03e-6)" "validated prognostic favorable (4.50e-4)" "unprognostic (6.44e-2)" "unprognostic (7.26e-2)" "unprognostic (5.23e-2)" "unprognostic (1.33e-1)" "unprognostic (1.45e-3)" "unprognostic (4.70e-2)" "unprognostic (2.07e-1)" "unprognostic (5.77e-2)" "unprognostic (6.07e-2)" "unprognostic (2.13e-1)" "unprognostic (1.66e-3)" "unprognostic (8.98e-2)" "unprognostic (4.03e-2)" "unprognostic (6.27e-2)" "unprognostic (1.10e-2)" "unprognostic (2.01e-1)" "unprognostic (2.46e-1)" "unprognostic (1.34e-1)" "unprognostic (1.81e-2)" DOCK7 "KIAA1771, ZIR2" ENSG00000116641 "Dedicator of cytokinesis 7" Q96N67 1 62454298-62688386 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein, Guanine-nucleotide releasing factor" Epilepsy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 532.4;Ependymal cells: 348.8;Retinal pigment epithelial cells: 694.9" "Cell type enhanced" "Detected in all" "astrocyte: 667.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.4" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 73: Brain - Neuronal signaling" "Cluster 39: Astrocytes - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 28: Astrocytes - Homeostasis & neuron support" 51 "unprognostic (5.61e-2)" "unprognostic (3.52e-1)" "unprognostic (2.96e-1)" "unprognostic (1.87e-2)" "unprognostic (2.44e-2)" "unprognostic (2.95e-1)" "unprognostic (6.11e-2)" "unprognostic (8.55e-2)" "unprognostic (1.27e-1)" "unprognostic (1.21e-1)" "potential prognostic favorable (1.10e-6)" "unprognostic (1.23e-1)" "unprognostic (1.04e-1)" "potential prognostic unfavorable (9.07e-5)" "unprognostic (2.81e-2)" "unprognostic (4.31e-2)" "unprognostic (8.22e-3)" "unprognostic (1.65e-1)" "unprognostic (1.97e-1)" "unprognostic (4.65e-2)" "unprognostic (7.75e-3)" "potential prognostic unfavorable (4.37e-4)" "unprognostic (1.24e-1)" "unprognostic (1.11e-1)" "unprognostic (4.95e-2)" "unprognostic (7.04e-2)" "unprognostic (1.59e-1)" "unprognostic (2.51e-1)" "unprognostic (1.67e-1)" "unprognostic (6.51e-2)" "unprognostic (1.21e-1)" DOCK8 "FLJ00026, FLJ00152, FLJ00346, ZIR8" ENSG00000107099 "Dedicator of cytokinesis 8" Q8NF50 9 214854-465259 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 35.7;lymphoid tissue: 57.8" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 1461.7;Microglia: 2809.4;Monocyte progenitors: 606.3;monocytes: 637.7;Neutrophil progenitors: 1121.6;Neutrophils: 2638.1;Thymocytes: 605.6" "Group enriched" "Detected in all" 7 "central nervous system macrophage: 3289.7;choroid plexus epithelial cell: 1065.3;leukocyte: 910.6" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "choroid plexus: 64.7" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Leukemia: 46.2;lymphoma: 39.0;Myeloma: 19.4" "Adrenal gland - Adrenal cortex cells, Thyroid gland - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA003218, HPA003219, HPA073349" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 19 "Plasma membrane, Cytosol" "HPA003218: , HPA003219: , HPA073349: " "unprognostic (5.68e-2)" "unprognostic (1.18e-1)" "potential prognostic favorable (6.03e-4)" "unprognostic (1.03e-1)" "unprognostic (1.90e-1)" "unprognostic (2.94e-1)" "unprognostic (2.62e-1)" "unprognostic (2.71e-2)" "unprognostic (6.05e-3)" "unprognostic (1.55e-1)" "validated prognostic favorable (2.87e-9)" "validated prognostic favorable (8.14e-4)" "potential prognostic favorable (1.76e-5)" "unprognostic (1.64e-1)" "unprognostic (4.16e-2)" "unprognostic (1.24e-2)" "unprognostic (1.08e-1)" "unprognostic (1.40e-1)" "unprognostic (2.62e-1)" "unprognostic (8.86e-2)" "unprognostic (1.51e-1)" "unprognostic (2.03e-1)" "unprognostic (8.79e-2)" "unprognostic (7.72e-2)" "unprognostic (4.22e-2)" "unprognostic (6.63e-2)" "unprognostic (2.64e-2)" "unprognostic (2.47e-1)" "unprognostic (2.72e-2)" "unprognostic (1.37e-1)" "unprognostic (1.21e-2)" DOCK9 "KIAA1058, ZIZ1" ENSG00000088387 "Dedicator of cytokinesis 9" Q9BZ29 13 98793429-99086625 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 1287.0;Lymphatic endothelial cells: 533.5;Oligodendrocytes: 544.3;Vascular endothelial cells: 686.1" "Cell type enhanced" "Detected in all" "endothelial cell: 1719.0" "Cancer enhanced" "Detected in all" "Thyroid Carcinoma (TCGA): 144.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "gdT-cell: 1.5;MAIT T-cell: 4.0;memory CD4 T-cell: 4.2;memory CD8 T-cell: 1.7;naive CD4 T-cell: 5.3;naive CD8 T-cell: 3.2;NK-cell: 6.1;T-reg: 1.9" "Group enriched" "Detected in many" 12 "NK-cells: 6.1;T-cells: 5.3" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034061, CAB034065, HPA043940" Uncertain NA NA "Cluster 11: T-cells - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 19: Non-specific - Unknown function" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 15 "CAB034061: , CAB034065: , HPA043940: " "unprognostic (1.09e-2)" "potential prognostic unfavorable (6.27e-4)" "unprognostic (1.52e-1)" "unprognostic (3.14e-2)" "unprognostic (6.77e-2)" "unprognostic (2.03e-1)" "unprognostic (1.59e-1)" "unprognostic (2.25e-1)" "unprognostic (1.54e-1)" "unprognostic (1.49e-3)" "validated prognostic favorable (1.93e-8)" "validated prognostic favorable (3.06e-5)" "unprognostic (9.48e-2)" "unprognostic (1.16e-1)" "unprognostic (2.28e-2)" "unprognostic (1.01e-2)" "unprognostic (5.55e-3)" "potential prognostic unfavorable (5.79e-4)" "unprognostic (4.31e-1)" "unprognostic (2.68e-2)" "unprognostic (1.39e-2)" "unprognostic (5.37e-3)" "unprognostic (6.17e-2)" "unprognostic (3.98e-1)" "unprognostic (2.15e-1)" "unprognostic (1.41e-1)" "unprognostic (1.54e-1)" "unprognostic (1.69e-1)" "unprognostic (1.57e-1)" "unprognostic (2.62e-2)" "unprognostic (2.40e-1)" DOHH "HLRC1, MGC4293" ENSG00000129932 "Deoxyhypusine hydroxylase" Q9BU89 19 3490821-3500674 "Enzymes, Predicted intracellular proteins" "Hypusine biosynthesis" "Monooxygenase, Oxidoreductase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 38.7" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 50.3;Esophageal suprabasal cells: 47.8" "Cell type enhanced" "Detected in all" "oligodendrocyte: 48.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041953, HPA076271" Approved Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 23: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 2 Cytosol "Nucleoplasm, Nucleoli" "HPA041953: , HPA076271: " "unprognostic (9.00e-2)" "unprognostic (1.36e-1)" "unprognostic (5.07e-2)" "unprognostic (2.57e-1)" "unprognostic (6.03e-2)" "unprognostic (1.72e-1)" "unprognostic (4.47e-1)" "unprognostic (4.10e-1)" "unprognostic (2.34e-3)" "unprognostic (2.35e-1)" "unprognostic (1.93e-2)" "unprognostic (1.23e-1)" "unprognostic (9.97e-2)" "unprognostic (1.62e-2)" "unprognostic (2.29e-2)" "unprognostic (2.11e-1)" "unprognostic (3.03e-2)" "unprognostic (5.89e-2)" "unprognostic (9.67e-2)" "unprognostic (5.62e-2)" "unprognostic (2.29e-1)" "unprognostic (4.08e-3)" "unprognostic (3.08e-1)" "unprognostic (1.16e-2)" "unprognostic (1.15e-1)" "unprognostic (1.02e-3)" "unprognostic (2.58e-1)" "unprognostic (1.95e-2)" "unprognostic (4.88e-1)" "unprognostic (1.17e-1)" "unprognostic (3.10e-3)" DOK1 p62dok ENSG00000115325 "Docking protein 1" Q99704 2 74549026-74557551 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 32.3;Hofbauer cells: 63.4;Megakaryocyte progenitors: 35.1;Megakaryocytes: 148.4;Microglia: 33.3;Platelets: 87.4" "Cell type enriched" "Detected in many" 4 "central nervous system macrophage: 38.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast), Lung - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004224, HPA048561" Approved Supported Cytosol NA NA 37000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 44: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 47: Platelets - Hemostasis" 22 Cytosol "CAB004224: , HPA048561: " "unprognostic (4.22e-1)" "unprognostic (3.35e-2)" "unprognostic (1.20e-3)" "unprognostic (5.23e-3)" "unprognostic (4.02e-2)" "unprognostic (1.65e-1)" "unprognostic (3.14e-3)" "potential prognostic unfavorable (1.69e-4)" "unprognostic (1.06e-1)" "unprognostic (2.47e-1)" "unprognostic (3.79e-2)" "unprognostic (8.65e-2)" "unprognostic (3.16e-3)" "unprognostic (9.35e-3)" "unprognostic (3.36e-1)" "potential prognostic favorable (1.23e-4)" "unprognostic (8.08e-2)" "unprognostic (8.43e-2)" "unprognostic (1.58e-1)" "potential prognostic unfavorable (2.35e-4)" "unprognostic (1.98e-1)" "unprognostic (7.43e-2)" "unprognostic (2.66e-2)" "unprognostic (1.01e-2)" "unprognostic (2.03e-1)" "unprognostic (9.02e-2)" "unprognostic (1.89e-1)" "unprognostic (7.87e-2)" "unprognostic (5.51e-2)" "unprognostic (1.21e-2)" "unprognostic (1.72e-2)" DOK2 "Dok-2, p56dok-2" ENSG00000147443 "Docking protein 2" O60496 8 21908873-21913690 "Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 24.2;lymphoid tissue: 44.0" "Cell type enhanced" "Detected in some" "cDC: 166.0;Hofbauer cells: 202.0;Kupffer cells: 186.5;Macrophages: 97.1;Megakaryocytes: 123.6;monocytes: 140.6;NK-cells: 146.1;Platelets: 559.2;T-cells: 96.2" "Cell type enriched" "Detected in single" 75 "leukocyte: 59.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "eosinophil: 1568.8" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 49 "Leukemia: 36.3;lymphoma: 9.8;Myeloma: 11.1" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Liver - Kupffer cells, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Skeletal muscle - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA002862, CAB004379, HPA066571, HPA069121" Enhanced Enhanced "Plasma membrane" NA NA 130000 "Cluster 25: Non-specific - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 17 "Plasma membrane" "CAB004379: , HPA002862: , HPA066571: , HPA069121: " "unprognostic (1.37e-1)" "unprognostic (6.10e-2)" "unprognostic (1.15e-3)" "unprognostic (5.51e-3)" "unprognostic (5.18e-2)" "unprognostic (2.27e-2)" "potential prognostic unfavorable (2.49e-4)" "unprognostic (8.09e-3)" "unprognostic (3.10e-3)" "unprognostic (2.67e-2)" "unprognostic (7.23e-2)" "unprognostic (2.70e-1)" "unprognostic (2.17e-1)" "unprognostic (1.60e-1)" "unprognostic (1.20e-1)" "unprognostic (5.37e-3)" "unprognostic (2.82e-1)" "unprognostic (1.01e-1)" "unprognostic (3.91e-1)" "unprognostic (3.47e-1)" "unprognostic (4.01e-2)" "unprognostic (8.88e-2)" "unprognostic (8.80e-3)" "unprognostic (6.47e-2)" "unprognostic (7.08e-2)" "unprognostic (6.62e-2)" "potential prognostic favorable (5.77e-5)" "unprognostic (3.14e-1)" "unprognostic (4.55e-3)" "unprognostic (1.93e-1)" "unprognostic (2.10e-1)" DOK3 FLJ22570 ENSG00000146094 "Docking protein 3" Q7L591 5 177501904-177511274 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 88.4;lymphoid tissue: 83.8" "Group enriched" "Detected in many" 4 "Neutrophil progenitors: 173.8;Neutrophils: 585.6" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 37.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 134.3" "Group enriched" "Detected in many" 6 "B-cells: 37.3;granulocytes: 134.3;monocytes: 78.1" "Group enriched" "Detected in all" 6 "Leukemia: 72.6;lymphoma: 95.9;Myeloma: 24.7" "Adipose subcutaneous - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Kidney - Macrophages, Lung - Neutrophils_2, Spleen - Neutrophils_2, Stomach - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA077312 Enhanced Supported "Nucleoplasm,Plasma membrane,Cytokinetic bridge,Cytosol" Yes NA 130000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 8 "Plasma membrane" "Nucleoplasm, Cytokinetic bridge, Cytosol" "HPA077312: " "unprognostic (2.77e-3)" "unprognostic (7.49e-2)" "unprognostic (6.01e-2)" "unprognostic (2.17e-1)" "unprognostic (7.50e-2)" "unprognostic (9.46e-2)" "unprognostic (2.30e-3)" "unprognostic (3.60e-1)" "unprognostic (1.56e-3)" "unprognostic (1.19e-2)" "potential prognostic unfavorable (8.04e-5)" "unprognostic (6.49e-2)" "unprognostic (1.71e-1)" "unprognostic (2.12e-2)" "unprognostic (2.94e-2)" "unprognostic (4.48e-2)" "unprognostic (7.96e-2)" "unprognostic (1.87e-1)" "unprognostic (1.59e-1)" "unprognostic (3.20e-1)" "unprognostic (6.09e-2)" "unprognostic (1.12e-2)" "unprognostic (2.27e-2)" "unprognostic (7.14e-2)" "unprognostic (2.44e-2)" "unprognostic (2.27e-1)" "unprognostic (2.04e-2)" "unprognostic (1.74e-1)" "unprognostic (1.06e-1)" "unprognostic (2.65e-1)" "unprognostic (6.82e-2)" DOK4 FLJ10488 ENSG00000125170 "Docking protein 4" Q8TEW6 16 57471922-57487327 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 94.8;Enterocytes: 99.4;Esophageal apical cells: 97.3;Esophageal suprabasal cells: 46.0;Foveolar cells: 53.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.3" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in all" "Neuroblastoma: 186.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008348, HPA055849" Supported Approved Cytosol NA No "Cluster 35: Neutrophils - Protein binding" "Cluster 77: Intestine - Digestion" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 28 Cytosol "HPA008348: , HPA055849: " "unprognostic (8.59e-3)" "unprognostic (5.36e-3)" "unprognostic (3.09e-1)" "unprognostic (1.81e-2)" "unprognostic (1.00e-1)" "unprognostic (9.48e-2)" "unprognostic (1.52e-1)" "unprognostic (5.29e-3)" "unprognostic (8.53e-2)" "unprognostic (2.59e-1)" "unprognostic (1.09e-3)" "unprognostic (1.07e-1)" "potential prognostic favorable (7.86e-5)" "unprognostic (7.08e-2)" "unprognostic (2.90e-2)" "unprognostic (1.61e-2)" "unprognostic (1.28e-1)" "unprognostic (2.00e-2)" "unprognostic (1.92e-1)" "unprognostic (1.94e-2)" "unprognostic (2.81e-2)" "unprognostic (1.23e-2)" "unprognostic (1.01e-1)" "unprognostic (4.51e-2)" "unprognostic (2.03e-1)" "unprognostic (5.08e-3)" "unprognostic (4.83e-2)" "unprognostic (3.21e-2)" "unprognostic (1.79e-1)" "unprognostic (1.74e-2)" "unprognostic (2.17e-1)" DOK5 "C20orf180, dJ805C22.1" ENSG00000101134 "Docking protein 5" Q9P104 20 54475593-54651169 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 43.1;tongue: 22.7" "Cell type enhanced" "Detected in many" "Astrocytes: 146.5;Choroid plexus epithelial cells: 123.0;Endometrial glandular cells: 93.6;Ependymal cells: 175.4;Epididymal basal cells: 82.5;Fallopian secretory cells: 80.2;Hofbauer cells: 107.2;Müller glia: 147.9;Myonuclei: 175.3;Oligodendrocyte progenitor cells: 104.2;Other brain neurons: 89.0;Retinal amacrine cells: 365.6;Retinal ganglion cells: 108.2;Retinal horizontal cells: 110.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 42.1;Ovary Serous Cystadenocarcinoma (TCGA): 44.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 8.1" "Lung - Fibroblasts_2, Prostate - Fibroblasts, Skeletal muscle - Skeletal myocytes, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054460, HPA065235" Uncertain Approved "Focal adhesion sites" NA NA "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 14: Neurons - Synaptic function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 1 "Focal adhesion sites" "HPA054460: , HPA065235: " "unprognostic (1.58e-1)" "unprognostic (3.58e-1)" "unprognostic (1.66e-1)" "unprognostic (3.14e-2)" "unprognostic (7.77e-3)" "unprognostic (1.32e-1)" "unprognostic (2.41e-2)" "unprognostic (1.51e-2)" "unprognostic (6.47e-2)" "unprognostic (1.57e-1)" "unprognostic (1.20e-1)" "unprognostic (3.74e-1)" "unprognostic (4.84e-3)" "unprognostic (3.23e-1)" "unprognostic (2.81e-1)" "unprognostic (7.54e-2)" "unprognostic (3.08e-1)" "unprognostic (1.42e-1)" "unprognostic (3.01e-1)" "unprognostic (4.38e-2)" "unprognostic (1.66e-1)" "unprognostic (1.68e-1)" "unprognostic (2.60e-1)" "unprognostic (1.05e-1)" "unprognostic (2.45e-3)" "unprognostic (2.48e-1)" "unprognostic (1.68e-2)" "unprognostic (5.48e-2)" DOK6 "DOK5L, HsT3226, MGC20785" ENSG00000206052 "Docking protein 6" Q6PKX4 18 69400888-69849087 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.9;parathyroid gland: 11.7;retina: 20.6" "Cell type enriched" "Detected in many" 4 "Retinal bipolar cells: 1939.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 6.4;testis cancer: 7.0" "Kidney - Proximal tubular cells, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041099, HPA063534" Approved Approved "Focal adhesion sites,Cytosol" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 24: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 11 "Focal adhesion sites, Cytosol" "HPA041099: , HPA063534: " "unprognostic (1.86e-1)" "unprognostic (3.38e-1)" "unprognostic (1.93e-1)" "unprognostic (7.34e-2)" "potential prognostic favorable (3.10e-6)" "validated prognostic favorable (7.51e-5)" "validated prognostic favorable (8.19e-4)" "potential prognostic unfavorable (5.49e-4)" "unprognostic (1.09e-2)" "unprognostic (2.52e-3)" "unprognostic (9.56e-2)" "unprognostic (3.23e-2)" "unprognostic (1.96e-1)" "unprognostic (3.96e-2)" DOK7 "C4orf25, Dok-7, FLJ33718, FLJ39137" ENSG00000175920 "Docking protein 7" Q18PE1 4 3463306-3501473 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 42.8;skeletal muscle: 31.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 16.4;Choroid plexus epithelial cells: 30.8;Epicardial cells: 22.7;Epididymal principal cells: 19.2;Gonadotrophs: 53.9;Lactotrophs: 33.1;Myonuclei: 32.8;Sertoli cells: 18.7;Somatotrophs: 35.1;Thymic myoid cells: 23.1;Thyrotrophs: 25.5" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 37.5" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 23.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 16 "memory B-cell: 3.4;naive B-cell: 2.3;NK-cell: 1.9" "Group enriched" "Detected in many" 16 "B-cells: 3.4;NK-cells: 1.9" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "HPA059449, HPA062780" Approved Enhanced Nucleoplasm,Mitochondria NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 3 Nucleoplasm Mitochondria "HPA059449: , HPA062780: " "unprognostic (5.25e-2)" "unprognostic (1.04e-3)" "unprognostic (5.70e-2)" "unprognostic (1.82e-1)" "unprognostic (9.91e-2)" "unprognostic (1.36e-2)" "unprognostic (3.09e-2)" "unprognostic (1.82e-2)" "unprognostic (2.63e-3)" "unprognostic (2.05e-2)" "unprognostic (7.00e-3)" "unprognostic (1.08e-1)" "unprognostic (3.48e-3)" "unprognostic (1.37e-1)" "unprognostic (1.60e-1)" "unprognostic (1.92e-1)" "unprognostic (8.72e-2)" "unprognostic (4.68e-3)" "unprognostic (1.23e-1)" "unprognostic (6.08e-2)" "unprognostic (4.37e-3)" "unprognostic (6.21e-2)" "potential prognostic favorable (5.11e-4)" DOLK "DK1, KIAA1094, TMEM15" ENSG00000175283 "Dolichol kinase" Q9UPQ8 9 128945530-128947603 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism" "Kinase, Transferase" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 30.5;Late primary spermatocytes: 32.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066767, HPA068706" Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 22: Epididymis - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 27 "Nucleoplasm, Nucleoli" Cytosol "HPA066767: , HPA068706: " "unprognostic (1.63e-3)" "unprognostic (8.14e-3)" "unprognostic (8.77e-2)" "unprognostic (3.72e-2)" "unprognostic (4.66e-1)" "unprognostic (1.97e-2)" "unprognostic (1.72e-1)" "unprognostic (2.31e-1)" "unprognostic (9.78e-3)" "unprognostic (2.24e-2)" "potential prognostic favorable (3.74e-4)" "unprognostic (1.10e-1)" "unprognostic (2.11e-2)" "unprognostic (1.09e-2)" "unprognostic (1.93e-2)" "unprognostic (1.30e-1)" "unprognostic (5.41e-2)" "unprognostic (2.32e-1)" "unprognostic (3.08e-2)" "unprognostic (1.99e-1)" "unprognostic (2.68e-1)" "unprognostic (1.10e-2)" "unprognostic (9.15e-2)" "unprognostic (7.87e-2)" "unprognostic (2.61e-1)" "unprognostic (9.47e-2)" "unprognostic (3.12e-1)" "unprognostic (1.95e-1)" "unprognostic (2.37e-1)" "unprognostic (3.97e-3)" "potential prognostic favorable (5.47e-5)" DOLPP1 LSFR2 ENSG00000167130 "Dolichyldiphosphatase 1" Q86YN1 9 129081111-129090438 "Enzymes, Metabolic proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 40.4;Esophageal apical cells: 25.4;Platelets: 26.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019179 Approved Approved "Vesicles,Intermediate filaments" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 77: Intestine - Digestion" "Cluster 45: Non-specific - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" Vesicles "Intermediate filaments" "HPA019179: " "potential prognostic unfavorable (3.80e-4)" "potential prognostic unfavorable (4.37e-4)" "unprognostic (9.99e-2)" "unprognostic (2.51e-2)" "unprognostic (2.68e-1)" "unprognostic (1.87e-2)" "unprognostic (4.39e-2)" "unprognostic (9.23e-3)" "unprognostic (2.63e-2)" "unprognostic (3.66e-1)" "unprognostic (2.17e-3)" "unprognostic (2.29e-2)" "unprognostic (3.67e-2)" "unprognostic (2.22e-1)" "unprognostic (2.02e-3)" "unprognostic (1.90e-1)" "unprognostic (1.23e-1)" "unprognostic (9.00e-2)" "unprognostic (3.94e-3)" "unprognostic (2.49e-2)" "unprognostic (4.40e-2)" "unprognostic (3.46e-1)" "unprognostic (2.02e-1)" "unprognostic (1.35e-2)" "unprognostic (8.07e-2)" "unprognostic (6.25e-2)" "unprognostic (9.21e-2)" "unprognostic (4.66e-2)" "unprognostic (1.24e-1)" "unprognostic (3.32e-1)" "unprognostic (4.81e-2)" DONSON "B17, C21orf60, C2TA, DKFZP434M035" ENSG00000159147 "DNA replication fork stabilization factor DONSON" Q9NYP3 21 33559542-33588706 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 7 "Cardiomyocytes: 513.7;Epicardial cells: 745.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039558, HPA049033" Uncertain Approved "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 39: Testis - Nuclear processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 6 "Nucleoplasm, Cell Junctions" Cytosol "HPA039558: , HPA049033: " "unprognostic (4.28e-2)" "unprognostic (2.82e-2)" "unprognostic (2.96e-1)" "unprognostic (4.79e-3)" "unprognostic (2.68e-2)" "unprognostic (4.64e-2)" "unprognostic (3.45e-1)" "unprognostic (2.23e-1)" "unprognostic (1.49e-2)" "unprognostic (5.67e-2)" "potential prognostic unfavorable (1.12e-7)" "unprognostic (4.14e-3)" "potential prognostic unfavorable (4.60e-4)" "potential prognostic unfavorable (2.38e-4)" "unprognostic (5.28e-3)" "unprognostic (2.76e-3)" "unprognostic (1.48e-3)" "unprognostic (4.89e-2)" "unprognostic (2.05e-2)" "unprognostic (2.79e-1)" "unprognostic (5.77e-3)" "unprognostic (8.43e-3)" "unprognostic (9.95e-2)" "unprognostic (5.47e-3)" "unprognostic (7.83e-3)" "unprognostic (2.66e-2)" "unprognostic (3.56e-3)" "unprognostic (2.27e-2)" "unprognostic (4.34e-2)" "unprognostic (1.68e-1)" "unprognostic (1.26e-3)" DOP1A "dJ202D23.2, DOPEY1, KIAA1117" ENSG00000083097 "DOP1 leucine zipper like protein A" Q5JWR5 6 83067666-83171350 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027902, HPA027904" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 42: Retina - Visual perception" "Cluster 31: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 79: Photoreceptor cells - Phototransduction" 1 Nucleoplasm Vesicles "HPA027902: , HPA027904: " "unprognostic (8.64e-2)" "unprognostic (1.34e-1)" "unprognostic (2.01e-2)" "unprognostic (1.09e-1)" "unprognostic (4.20e-1)" "unprognostic (9.89e-3)" "potential prognostic favorable (8.76e-4)" "unprognostic (2.49e-2)" "unprognostic (6.25e-2)" "validated prognostic favorable (4.78e-5)" "validated prognostic favorable (6.40e-5)" "unprognostic (7.57e-2)" "unprognostic (3.35e-3)" "unprognostic (1.03e-1)" "unprognostic (5.67e-2)" "unprognostic (4.25e-2)" "unprognostic (1.47e-1)" "unprognostic (2.56e-1)" "unprognostic (1.86e-1)" "unprognostic (1.20e-1)" "unprognostic (3.39e-1)" "unprognostic (9.87e-3)" "unprognostic (8.75e-2)" "unprognostic (3.44e-1)" "unprognostic (3.21e-1)" "unprognostic (3.54e-1)" "unprognostic (4.17e-3)" "unprognostic (8.31e-2)" DOP1B "C21orf5, DOPEY2, KIAA0933" ENSG00000142197 "DOP1 leucine zipper like protein B" Q9Y3R5 21 36156782-36294274 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 24.1" "Cell type enhanced" "Detected in many" "Foveolar cells: 182.8;Goblet cells: 250.1;Neutrophil progenitors: 418.9;Prostatic glandular cells: 194.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 5.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Stomach - Gastric mucous cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072065 Enhanced Approved Nucleoplasm,Mitochondria Yes No "Cluster 23: B-cells - Immunoglobulins" "Cluster 76: Non-specific - Metabolism" "Cluster 15: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 37: Neutrophil progenitors - Granulopoiesis" Nucleoplasm Mitochondria "HPA072065: " "unprognostic (3.10e-1)" "potential prognostic unfavorable (1.67e-4)" "unprognostic (3.77e-1)" "unprognostic (7.23e-2)" "unprognostic (2.80e-2)" "unprognostic (1.75e-1)" "unprognostic (1.73e-1)" "unprognostic (9.38e-2)" "unprognostic (4.10e-1)" "potential prognostic favorable (1.60e-4)" "unprognostic (1.08e-2)" "unprognostic (1.65e-1)" "unprognostic (9.57e-3)" "unprognostic (2.96e-1)" "unprognostic (2.42e-2)" "unprognostic (1.48e-2)" "unprognostic (1.53e-1)" "unprognostic (8.15e-2)" "unprognostic (2.44e-1)" "unprognostic (5.89e-2)" "unprognostic (3.27e-2)" "unprognostic (1.50e-1)" "unprognostic (1.46e-2)" "unprognostic (3.99e-2)" "unprognostic (1.64e-1)" "unprognostic (1.41e-2)" "unprognostic (3.44e-2)" "unprognostic (3.20e-1)" "unprognostic (2.50e-2)" DOT1L "DOT1, KIAA1814, KMT4" ENSG00000104885 "DOT1 like histone lysine methyltransferase" Q8TEK3 19 2163933-2232578 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Chromatin regulator, DNA-binding, Methyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 49.2" "Cell type enhanced" "Detected in many" "Neutrophils: 140.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Kidney - Macrophages, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011875, HPA071217, HPA074977" Uncertain Enhanced Nucleoplasm NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 67: Testis - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 23: Non-specific - Transcription" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 32 Nucleoplasm "HPA011875: , HPA071217: , HPA074977: " "unprognostic (5.58e-2)" "unprognostic (5.82e-3)" "unprognostic (1.45e-2)" "unprognostic (9.62e-2)" "unprognostic (2.04e-1)" "unprognostic (1.03e-1)" "unprognostic (1.48e-1)" "unprognostic (2.06e-2)" "potential prognostic favorable (5.68e-4)" "unprognostic (2.04e-2)" "unprognostic (2.66e-1)" "unprognostic (6.88e-2)" "unprognostic (2.17e-2)" "potential prognostic unfavorable (7.82e-4)" "unprognostic (4.19e-2)" "unprognostic (1.82e-2)" "unprognostic (3.26e-2)" "unprognostic (1.59e-1)" "unprognostic (7.42e-2)" "unprognostic (2.42e-2)" "unprognostic (9.90e-3)" "unprognostic (1.61e-3)" "potential prognostic unfavorable (6.87e-4)" "potential prognostic unfavorable (6.69e-4)" "unprognostic (1.04e-1)" "unprognostic (1.56e-2)" "unprognostic (1.97e-2)" "unprognostic (1.45e-3)" "unprognostic (2.94e-1)" "unprognostic (4.39e-2)" "unprognostic (2.21e-1)" DPAGT1 "ALG7, CDG-Ij, D11S366, DGPT, DPAGT, DPAGT2, GPT" ENSG00000172269 "Dolichyl-phosphate N-acetylglucosaminephosphotransferase 1" Q9H3H5 11 119096025-119108331 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 57.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053878 Approved NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 70: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 24: Non-specific - Unknown function" "Cluster 8: Non-specific - Secretory pathway" 1 "HPA053878: " "unprognostic (2.89e-1)" "unprognostic (1.30e-2)" "unprognostic (2.09e-1)" "unprognostic (4.72e-2)" "unprognostic (3.05e-1)" "unprognostic (1.92e-2)" "unprognostic (1.65e-1)" "unprognostic (1.84e-1)" "unprognostic (4.66e-2)" "unprognostic (9.85e-2)" "unprognostic (3.03e-3)" "unprognostic (3.98e-2)" "unprognostic (2.72e-1)" "potential prognostic unfavorable (2.69e-4)" "unprognostic (2.05e-2)" "potential prognostic unfavorable (7.69e-4)" "unprognostic (8.25e-2)" "unprognostic (1.05e-1)" "unprognostic (3.39e-1)" "unprognostic (1.24e-1)" "unprognostic (2.60e-1)" "unprognostic (5.89e-3)" "unprognostic (4.66e-1)" "unprognostic (2.60e-2)" "unprognostic (3.52e-2)" "unprognostic (8.62e-2)" "unprognostic (1.34e-1)" "unprognostic (1.18e-2)" "unprognostic (1.13e-2)" "unprognostic (2.48e-1)" "unprognostic (9.19e-2)" DPCD "DKFZP566F084, RP11-529I10.4" ENSG00000166171 "Deleted in primary ciliary dyskinesia homolog (mouse)" Q9BVM2 10 101570560-101609662 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 141.8;testis: 135.5" "Cell type enhanced" "Detected in many" "Early spermatids: 497.6;Epididymal efferent duct ciliated cells: 254.8;Fallopian tube ciliated cells: 310.1;Late primary spermatocytes: 886.4;Late spermatids: 1610.2;Respiratory ciliated cells: 316.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 20.3;intermediate monocyte: 22.3;myeloid DC: 29.7;non-classical monocyte: 9.5" "Group enriched" "Detected in all" 14 "dendritic cells: 29.7;monocytes: 22.3" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Liver - Vascular endothelial cells, Lung - Respiratory ciliated cells, Pituitary gland - Somatotropes, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036603, HPA036604" Enhanced Approved "Nucleoplasm,Vesicles,Plasma membrane,Mitotic spindle,Primary cilium" Yes NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 16 "Nucleoplasm, Vesicles" "Plasma membrane, Mitotic spindle, Primary cilium" "HPA036603: , HPA036604: " "unprognostic (2.02e-2)" "unprognostic (1.19e-1)" "unprognostic (1.37e-1)" "unprognostic (4.81e-2)" "unprognostic (1.31e-1)" "unprognostic (6.03e-2)" "unprognostic (9.74e-2)" "unprognostic (2.36e-2)" "unprognostic (1.42e-1)" "potential prognostic unfavorable (7.58e-4)" "unprognostic (3.55e-2)" "unprognostic (4.67e-1)" "unprognostic (1.13e-2)" "unprognostic (1.14e-3)" "unprognostic (3.46e-3)" "unprognostic (1.34e-2)" "unprognostic (1.39e-3)" "unprognostic (2.40e-1)" "unprognostic (6.92e-2)" "unprognostic (1.69e-1)" "unprognostic (3.33e-3)" "unprognostic (6.75e-2)" "unprognostic (1.67e-1)" "unprognostic (1.11e-1)" "unprognostic (2.01e-1)" "unprognostic (1.36e-1)" "unprognostic (3.95e-1)" "unprognostic (1.30e-1)" "unprognostic (7.39e-3)" "unprognostic (6.79e-3)" "unprognostic (5.57e-3)" DPEP1 ENSG00000015413 "Dipeptidase 1" P16444 16 89613308-89638456 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Dipeptidase, Hydrolase, Metalloprotease, Protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "intestine: 364.7;kidney: 245.4;pancreas: 477.7" "Group enriched" "Detected in many" 8 "Enterocytes: 4466.3;Peritubular myoid cells: 1128.1" "Cell type enhanced" "Detected in some" "ependymal cell: 3.9" "Group enriched" "Detected in many" 5 "Colon Adenocarcinoma (TCGA): 177.2;Rectum Adenocarcinoma (TCGA): 210.7" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "colorectal cancer: 134.1" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Minor Salivary Gland - Plasma cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Spleen - Plasma cells, Stomach - Gastric enteroendocrine cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA009426, HPA012783" Enhanced Approved "Nucleoplasm,Cell Junctions" "Intracellular and membrane" Enzyme NA NA 240000 "Cluster 60: Stomach - Digestion" "Cluster 46: Brainstem - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 1: Enterocytes - Absorption and Digestion" 21 "Nucleoplasm, Cell Junctions" "HPA009426: , HPA012783: " "unprognostic (7.53e-2)" "unprognostic (3.14e-2)" "unprognostic (2.54e-1)" "unprognostic (1.94e-1)" "unprognostic (3.09e-1)" "unprognostic (2.17e-2)" "unprognostic (3.61e-2)" "unprognostic (2.43e-1)" "potential prognostic favorable (7.23e-5)" "unprognostic (5.49e-3)" "unprognostic (3.41e-2)" "unprognostic (9.61e-2)" "unprognostic (2.73e-1)" "unprognostic (2.16e-1)" "unprognostic (7.48e-2)" "unprognostic (1.52e-2)" "unprognostic (8.28e-3)" "unprognostic (3.01e-1)" "unprognostic (6.14e-2)" "unprognostic (3.09e-2)" "unprognostic (8.77e-3)" "unprognostic (6.57e-2)" "unprognostic (3.45e-1)" "unprognostic (1.23e-2)" "unprognostic (2.91e-1)" "unprognostic (1.39e-1)" DPEP2 ENSG00000167261 "Dipeptidase 2" Q9H4A9 16 67987394-68000586 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Dipeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 22.0;lymphoid tissue: 27.4" "Cell type enhanced" "Detected in many" "B-cells: 49.2;cDC: 41.3;Kupffer cells: 105.6;Macrophages: 44.3;Microglia: 28.9;monocytes: 49.4;Neutrophil progenitors: 41.0;Neutrophils: 235.8;NK-cells: 35.7;Syncytiotrophoblasts: 108.6;Thymocytes: 32.2" "Group enriched" "Detected in some" 8 "central nervous system macrophage: 38.2;endothelial cell: 32.1;leukocyte: 37.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 411.4;eosinophil: 844.3;neutrophil: 361.3" "Lineage enriched" "Detected in all" 7 "granulocytes: 844.3" "Cancer enriched" "Detected in some" 5 "Leukemia: 6.0" "Kidney - T-cells" "Not detected" "Not detected" "Region enhanced" "Detected in many" "midbrain: 16.6" HPA035644 Approved NA NA 49000000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" "HPA035644: " "unprognostic (3.12e-2)" "unprognostic (3.05e-1)" "unprognostic (5.79e-2)" "potential prognostic favorable (1.51e-5)" "unprognostic (1.10e-1)" "unprognostic (6.23e-2)" "unprognostic (8.54e-2)" "unprognostic (7.18e-2)" "unprognostic (4.59e-2)" "unprognostic (3.11e-1)" "unprognostic (4.26e-3)" "unprognostic (1.69e-2)" "potential prognostic favorable (2.51e-4)" "unprognostic (1.87e-1)" "unprognostic (4.33e-2)" "potential prognostic favorable (3.35e-4)" "unprognostic (9.35e-2)" "unprognostic (8.10e-2)" "unprognostic (6.43e-2)" "unprognostic (1.66e-1)" "unprognostic (9.04e-2)" "unprognostic (1.88e-2)" "unprognostic (2.18e-1)" "unprognostic (8.41e-2)" "unprognostic (1.01e-1)" "unprognostic (3.52e-2)" "unprognostic (7.97e-2)" "unprognostic (3.30e-2)" "unprognostic (1.97e-3)" "unprognostic (4.51e-2)" "unprognostic (1.32e-1)" DPEP2NB ENSG00000263201 "DPEP2 neighbor" A0A0U1RQF7 16 68013436-68015911 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 5 "testis: 3.9" "Cell type enriched" "Detected in some" 4 "Syncytiotrophoblasts: 84.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "eosinophil: 1.0" "Lineage enriched" "Detected in single" 11 "granulocytes: 1.0" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 6 DPEP3 ENSG00000141096 "Dipeptidase 3" Q9H4B8 16 67975663-67980549 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 28 "testis: 54.8" "Group enriched" "Detected in some" 6 "Differentiating spermatogonia: 313.9;Early primary spermatocytes: 428.2" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "Ovary Serous Cystadenocarcinoma (TCGA): 25.5;Skin Cutaneous Melanoma (TCGA): 7.9;Testicular Germ Cell Tumor (TCGA): 9.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "neutrophil: 6.7;NK-cell: 1.8" "Group enriched" "Detected in many" 8 "granulocytes: 6.7;NK-cells: 1.8" "Cancer enhanced" "Detected in some" "cervical cancer: 17.2" "Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA031870, HPA058607" Enhanced NA NA 29000000 "Cluster 35: Neutrophils - Protein binding" "Cluster 23: Testis - Spermatogenesis" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 3: Early primary spermatocytes - Early meiosis" 1 "HPA031870: , HPA058607: " "unprognostic (5.89e-2)" "unprognostic (8.30e-3)" "unprognostic (3.13e-1)" "unprognostic (3.75e-2)" "unprognostic (5.09e-2)" "unprognostic (1.36e-1)" "unprognostic (1.04e-3)" "unprognostic (4.81e-2)" "unprognostic (2.57e-1)" DPF1 "BAF45b, NEUD4, neuro-d4, SMARCG1" ENSG00000011332 "Double PHD fingers 1" Q92782 19 38211006-38229714 "Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "brain: 30.9" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 26.0;Brain inhibitory neurons: 31.2;Early primary spermatocytes: 15.3;Early spermatids: 35.1;Late spermatids: 48.2;Oligodendrocyte progenitor cells: 32.2;Other brain neurons: 24.0;Retinal amacrine cells: 29.5;Retinal bipolar cells: 16.1;Retinal ganglion cells: 19.3;Retinal horizontal cells: 28.0;Sertoli cells: 24.9" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 6 "Glioblastoma Multiforme (TCGA): 20.5;Testicular Germ Cell Tumor (TCGA): 14.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Neuroblastoma: 24.6" "Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049148 Enhanced Approved Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" 30 "Nucleoplasm, Cytosol" Mitochondria "HPA049148: " "unprognostic (7.86e-2)" "unprognostic (1.92e-1)" "unprognostic (8.66e-2)" "unprognostic (7.04e-2)" "unprognostic (2.15e-3)" "unprognostic (3.43e-1)" "unprognostic (2.64e-2)" "unprognostic (2.96e-1)" "unprognostic (7.45e-2)" "unprognostic (1.26e-1)" "unprognostic (3.84e-1)" "unprognostic (3.22e-2)" DPF2 "BAF45d, REQ, SMARCG2, ubi-d4" ENSG00000133884 "Double PHD fingers 2" Q92785 11 65333843-65354262 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" "Chromatin regulator" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 179.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020880, HPA056786" Approved Supported Nucleoplasm,Vesicles,Centrosome,Cytosol NA NA "Cluster 41: Basophils - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 94: Gonadal somatic cells - Mixed function" 76 Nucleoplasm "Vesicles, Centrosome, Cytosol" "HPA020880: , HPA056786: " "unprognostic (3.84e-2)" "unprognostic (1.92e-2)" "unprognostic (1.96e-1)" "unprognostic (7.07e-3)" "unprognostic (1.95e-3)" "unprognostic (2.36e-3)" "unprognostic (2.31e-2)" "unprognostic (7.41e-3)" "unprognostic (4.06e-2)" "unprognostic (3.49e-3)" "unprognostic (1.73e-2)" "unprognostic (6.95e-2)" "unprognostic (1.96e-1)" "potential prognostic unfavorable (8.11e-5)" "unprognostic (1.69e-2)" "unprognostic (8.32e-2)" "potential prognostic unfavorable (9.13e-7)" "unprognostic (2.46e-2)" "unprognostic (1.69e-1)" "unprognostic (2.50e-1)" "unprognostic (1.52e-1)" "unprognostic (2.16e-1)" "unprognostic (2.66e-3)" "unprognostic (2.14e-1)" "unprognostic (4.03e-1)" "unprognostic (2.39e-1)" "unprognostic (3.70e-1)" "unprognostic (3.87e-2)" "unprognostic (4.07e-2)" "unprognostic (1.39e-2)" "unprognostic (8.22e-2)" DPF3 "BAF45c, cer-d4, Cerd4, FLJ14079, SMARCG3" ENSG00000205683 "Double PHD fingers 3" Q92784 14 72609034-72894101 "Predicted intracellular proteins" "Myogenesis, Neurogenesis, Transcription, Transcription regulation" "Activator, Chromatin regulator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 16.4;heart muscle: 3.9;retina: 4.8" "Cell type enhanced" "Detected in many" "Astrocytes: 200.4;Cardiomyocytes: 739.1;Cone photoreceptor cells: 724.5;Granulosa cells: 200.3;Myonuclei: 957.9;Oligodendrocyte progenitor cells: 161.4;Retinal amacrine cells: 235.9;Rod photoreceptor cells: 472.5" "Cell type enhanced" "Detected in all" "hippocampal CA4: 365.3;upper rhombic lip: 346.5" "Cancer enriched" "Detected in some" 8 "Glioblastoma Multiforme (TCGA): 8.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Stomach - Parietal cells, Testis - Early spermatids, Testis - Late spermatids" "Region enhanced" "Detected in all" "cerebellum: 49.5" "Low region specificity" "Detected in all" "HPA066790, HPA070601" Enhanced Enhanced Nucleoplasm NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 35: Non-specific - DNA binding" "Cluster 72: Neuronal - Signal transduction" "Cluster 55: Myocytes - Oxidative muscle function" 29 Nucleoplasm "HPA066790: , HPA070601: " "unprognostic (1.11e-1)" "unprognostic (2.60e-2)" "unprognostic (2.86e-1)" "unprognostic (1.11e-1)" "unprognostic (1.07e-1)" "unprognostic (2.55e-1)" "unprognostic (7.20e-2)" "unprognostic (4.37e-3)" "unprognostic (1.39e-2)" "unprognostic (9.82e-2)" DPH1 "DPH2L, DPH2L1, OVCA1" ENSG00000108963 "Diphthamide biosynthesis 1" Q9BZG8 17 2030137-2043898 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant, Dwarfism, Ectodermal dysplasia, Hypotrichosis, Intellectual disability, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 14 "Epicardial cells: 825.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069750, HPA073864" Approved Approved "Nucleoplasm,Cell Junctions" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 24: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 42: Non-specific - Unknown function" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 5 Nucleoplasm "Cell Junctions" "HPA069750: , HPA073864: " "unprognostic (6.16e-2)" "unprognostic (7.65e-2)" "unprognostic (1.01e-1)" "unprognostic (2.21e-1)" "unprognostic (4.91e-2)" "unprognostic (7.31e-2)" "unprognostic (5.64e-2)" "unprognostic (1.69e-2)" "unprognostic (7.96e-2)" "unprognostic (3.76e-1)" "potential prognostic favorable (2.77e-5)" "unprognostic (1.10e-1)" "unprognostic (9.91e-3)" "unprognostic (1.81e-1)" "unprognostic (2.23e-2)" "unprognostic (4.15e-1)" "unprognostic (2.77e-1)" "unprognostic (2.10e-1)" "unprognostic (1.67e-1)" "unprognostic (4.36e-1)" "unprognostic (1.11e-1)" "potential prognostic favorable (5.59e-4)" "unprognostic (1.19e-1)" "unprognostic (1.97e-2)" "unprognostic (4.43e-2)" "unprognostic (1.88e-1)" "unprognostic (2.04e-1)" "unprognostic (2.63e-1)" "unprognostic (2.30e-1)" "unprognostic (6.34e-2)" "unprognostic (6.25e-2)" DPH2 DPH2L2 ENSG00000132768 "Diphthamide biosynthesis 2" Q9BQC3 1 43970000-43973369 "Disease related genes, Predicted intracellular proteins" "Disease variant, Dwarfism, Ectodermal dysplasia, Hypotrichosis, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 38.9;Esophageal basal cells: 28.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028119, HPA061083" Approved Approved "Endoplasmic reticulum,Cytosol" NA No "Cluster 13: Non-specific - Mitochondria" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 13 Cytosol "Endoplasmic reticulum" "HPA028119: , HPA061083: " "unprognostic (1.17e-3)" "unprognostic (5.43e-2)" "unprognostic (6.21e-2)" "unprognostic (1.49e-2)" "unprognostic (2.34e-2)" "unprognostic (7.27e-2)" "unprognostic (4.85e-2)" "unprognostic (4.94e-3)" "unprognostic (2.85e-1)" "unprognostic (3.69e-1)" "unprognostic (2.55e-3)" "unprognostic (2.89e-1)" "unprognostic (1.95e-1)" "validated prognostic unfavorable (4.44e-10)" "validated prognostic unfavorable (5.20e-6)" "unprognostic (1.37e-1)" "unprognostic (1.81e-2)" "unprognostic (1.33e-1)" "unprognostic (7.84e-2)" "unprognostic (2.59e-1)" "unprognostic (1.54e-2)" "unprognostic (9.62e-3)" "unprognostic (2.98e-1)" "unprognostic (1.39e-2)" "unprognostic (2.67e-2)" "unprognostic (1.51e-1)" "unprognostic (1.28e-1)" "unprognostic (1.39e-2)" "unprognostic (2.36e-1)" "unprognostic (9.97e-3)" "unprognostic (1.05e-1)" DPH3 "DELGIP, DELGIP1, DESR1, DPH3A, KTI11, MGC20197, ZCSL2" ENSG00000154813 "Diphthamide biosynthesis 3" Q96FX2 3 16257061-16264969 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 180.0;Hofbauer cells: 149.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035287 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 97: Non-specific - Cellular respiration" 5 Nucleoplasm Cytosol "HPA035287: " "unprognostic (1.48e-1)" "unprognostic (4.54e-2)" "unprognostic (4.03e-2)" "unprognostic (3.90e-1)" "unprognostic (1.62e-1)" "unprognostic (9.60e-2)" "unprognostic (2.55e-1)" "potential prognostic unfavorable (7.90e-6)" "unprognostic (1.73e-1)" "unprognostic (8.16e-3)" "potential prognostic favorable (6.26e-5)" "unprognostic (3.28e-2)" "unprognostic (6.91e-2)" "unprognostic (2.02e-3)" "unprognostic (1.85e-3)" "unprognostic (1.04e-1)" "unprognostic (3.48e-1)" "unprognostic (4.65e-2)" "unprognostic (3.01e-1)" "unprognostic (1.08e-1)" "unprognostic (1.97e-2)" "unprognostic (6.07e-2)" "unprognostic (1.44e-2)" "unprognostic (1.40e-2)" "unprognostic (1.21e-1)" "unprognostic (8.43e-2)" "unprognostic (1.11e-1)" "unprognostic (3.15e-2)" "unprognostic (1.88e-1)" "unprognostic (1.71e-2)" "unprognostic (1.14e-1)" DPH5 CGI-30 ENSG00000117543 "Diphthamide biosynthesis 5" Q9H2P9 1 100989623-101026088 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 132.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046439, HPA076234" Approved Approved "Nucleoli,Golgi apparatus" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 25: Non-specific - Ribosome" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" "Golgi apparatus" Nucleoli "HPA046439: , HPA076234: " "potential prognostic unfavorable (1.27e-4)" "unprognostic (1.03e-1)" "unprognostic (3.98e-1)" "unprognostic (3.77e-2)" "unprognostic (1.24e-2)" "unprognostic (6.96e-2)" "unprognostic (1.56e-2)" "unprognostic (1.79e-3)" "unprognostic (6.70e-2)" "unprognostic (5.96e-2)" "unprognostic (1.01e-2)" "unprognostic (8.18e-2)" "unprognostic (7.96e-2)" "unprognostic (2.16e-3)" "unprognostic (8.38e-3)" "unprognostic (7.19e-2)" "unprognostic (8.60e-2)" "potential prognostic favorable (6.16e-4)" "unprognostic (3.12e-1)" "unprognostic (6.13e-2)" "unprognostic (1.37e-1)" "unprognostic (1.19e-2)" "unprognostic (5.59e-2)" "unprognostic (2.09e-3)" "potential prognostic favorable (7.72e-4)" "unprognostic (1.01e-1)" "unprognostic (3.83e-2)" "unprognostic (1.15e-2)" "unprognostic (2.71e-1)" "unprognostic (2.69e-1)" "unprognostic (1.82e-2)" DPH6 "ATPBD4, MGC14798" ENSG00000134146 "Diphthamine biosynthesis 6" Q7L8W6 15 35217345-35546193 "Enzymes, Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042976, HPA055496" Approved Approved "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 54: Non-specific - Ribosome" "Cluster 55: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" 1 "Nucleoli, Nucleoli rim" Nucleoplasm "HPA042976: , HPA055496: " "unprognostic (2.23e-1)" "unprognostic (1.13e-2)" "unprognostic (3.40e-2)" "unprognostic (7.56e-2)" "unprognostic (1.22e-1)" "unprognostic (1.44e-1)" "unprognostic (3.22e-2)" "unprognostic (3.78e-3)" "unprognostic (8.72e-2)" "validated prognostic favorable (1.89e-5)" "validated prognostic favorable (4.48e-4)" "unprognostic (8.67e-2)" "unprognostic (4.56e-2)" "unprognostic (7.20e-3)" "unprognostic (3.67e-3)" "unprognostic (3.30e-2)" "unprognostic (1.48e-2)" "unprognostic (2.15e-2)" "unprognostic (5.61e-2)" "potential prognostic unfavorable (2.93e-6)" "unprognostic (6.50e-3)" "unprognostic (3.11e-1)" "unprognostic (8.60e-2)" "unprognostic (2.70e-1)" "unprognostic (8.18e-2)" "unprognostic (3.48e-2)" "unprognostic (1.31e-1)" "unprognostic (3.75e-1)" "unprognostic (2.19e-1)" DPH7 "C9orf112, FLJ90634, RRT2, WDR85" ENSG00000148399 "Diphthamide biosynthesis 7" Q9BTV6 9 137554444-137578925 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Early primary spermatocytes: 289.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022911 Uncertain Approved "Nuclear bodies" Yes No "Cluster 46: Basophils - Proteolysis" "Cluster 70: Non-specific - Protein processing" "Cluster 11: White matter - Signal transduction" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 3: Early primary spermatocytes - Early meiosis" 7 "Nuclear bodies" "HPA022911: " "unprognostic (4.41e-3)" "unprognostic (4.61e-3)" "unprognostic (1.38e-1)" "unprognostic (2.45e-1)" "unprognostic (3.10e-1)" "unprognostic (6.12e-2)" "potential prognostic favorable (2.37e-5)" "unprognostic (5.89e-2)" "unprognostic (2.77e-1)" "unprognostic (2.15e-2)" "unprognostic (6.47e-3)" "unprognostic (4.77e-2)" "potential prognostic unfavorable (2.15e-4)" "unprognostic (7.07e-2)" "unprognostic (1.75e-1)" "unprognostic (3.40e-1)" "unprognostic (1.69e-2)" "unprognostic (1.02e-1)" "unprognostic (1.14e-2)" "unprognostic (2.22e-2)" "unprognostic (2.37e-3)" "unprognostic (5.92e-2)" "potential prognostic favorable (3.46e-4)" "unprognostic (6.85e-3)" "unprognostic (7.78e-2)" "unprognostic (2.08e-2)" "unprognostic (9.41e-2)" "unprognostic (9.85e-2)" "unprognostic (4.27e-1)" DPM1 "CDGIE, MPDS" ENSG00000000419 "Dolichyl-phosphate mannosyltransferase subunit 1, catalytic" O60762 20 50934867-50959140 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Congenital muscular dystrophy, Disease variant, Dystroglycanopathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 272.5;Syncytiotrophoblasts: 337.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051818 Approved NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 62: Non-specific - Plasma proteins" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 22 "HPA051818: " "unprognostic (1.36e-1)" "unprognostic (2.05e-2)" "unprognostic (6.36e-2)" "unprognostic (1.28e-1)" "unprognostic (9.08e-2)" "unprognostic (1.25e-1)" "unprognostic (1.21e-2)" "unprognostic (1.15e-1)" "potential prognostic unfavorable (6.80e-4)" "unprognostic (1.46e-2)" "unprognostic (3.22e-3)" "unprognostic (1.99e-1)" "unprognostic (1.38e-2)" "validated prognostic unfavorable (5.68e-7)" "validated prognostic unfavorable (8.11e-4)" "unprognostic (8.94e-2)" "unprognostic (3.96e-2)" "unprognostic (9.83e-2)" "unprognostic (1.91e-1)" "unprognostic (1.02e-1)" "unprognostic (1.09e-3)" "unprognostic (5.86e-3)" "unprognostic (4.80e-3)" "unprognostic (5.21e-2)" "unprognostic (3.10e-3)" "unprognostic (6.53e-3)" "unprognostic (7.55e-2)" "unprognostic (4.26e-1)" "unprognostic (1.48e-1)" "potential prognostic unfavorable (9.78e-4)" "unprognostic (2.18e-1)" DPM2 "MGC111193, MGC21559" ENSG00000136908 "Dolichyl-phosphate mannosyltransferase subunit 2, regulatory" O94777 9 127935099-127937854 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Congenital disorder of glycosylation, Congenital muscular dystrophy, Disease variant, Dystroglycanopathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 132.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064623 Approved NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 38: Sub-cortical - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Secretory pathway" 4 "HPA064623: " "unprognostic (2.27e-3)" "unprognostic (2.69e-2)" "unprognostic (1.22e-2)" "unprognostic (3.87e-1)" "unprognostic (7.51e-3)" "potential prognostic unfavorable (8.85e-4)" "unprognostic (1.58e-1)" "potential prognostic favorable (9.89e-4)" "unprognostic (1.31e-2)" "unprognostic (2.65e-1)" "unprognostic (1.30e-2)" "unprognostic (6.96e-2)" "potential prognostic favorable (2.15e-4)" "potential prognostic unfavorable (1.28e-4)" "unprognostic (7.14e-2)" "unprognostic (2.37e-1)" "unprognostic (9.68e-2)" "unprognostic (8.73e-2)" "unprognostic (4.13e-2)" "unprognostic (7.53e-2)" "unprognostic (8.64e-2)" "unprognostic (2.10e-2)" "unprognostic (3.93e-2)" "unprognostic (1.36e-1)" "unprognostic (4.88e-2)" "unprognostic (3.83e-2)" "unprognostic (1.25e-1)" "unprognostic (6.26e-3)" "unprognostic (1.54e-1)" "unprognostic (2.93e-1)" "unprognostic (3.92e-2)" DPM3 "MGC125904, MGC125905, MGC34275" ENSG00000179085 "Dolichyl-phosphate mannosyltransferase subunit 3, regulatory" Q9P2X0 1 155139891-155140595 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Congenital disorder of glycosylation, Congenital muscular dystrophy, Disease variant, Dystroglycanopathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 361.1;Hepatocytes: 289.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014667 Approved NA NA 1300000 "Cluster 29: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 45: Non-specific - Nuclear processes" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 4 "HPA014667: " "unprognostic (3.41e-1)" "unprognostic (2.17e-2)" "unprognostic (2.42e-1)" "unprognostic (1.81e-2)" "unprognostic (2.55e-1)" "unprognostic (4.31e-2)" "unprognostic (9.33e-2)" "unprognostic (3.11e-1)" "unprognostic (8.49e-2)" "unprognostic (1.04e-1)" "unprognostic (4.32e-2)" "unprognostic (1.07e-1)" "unprognostic (1.30e-1)" "unprognostic (1.44e-2)" "unprognostic (2.37e-1)" "unprognostic (4.86e-2)" "unprognostic (1.24e-1)" "unprognostic (1.53e-1)" "unprognostic (1.31e-2)" "potential prognostic favorable (7.41e-6)" "unprognostic (5.26e-2)" "unprognostic (1.59e-3)" "unprognostic (1.52e-2)" "unprognostic (3.18e-2)" "unprognostic (3.23e-2)" "unprognostic (1.74e-1)" "unprognostic (2.56e-1)" "unprognostic (4.39e-2)" "unprognostic (1.36e-1)" "unprognostic (4.89e-1)" "unprognostic (4.09e-2)" DPP10 "DPL2, DPPY, DPRP3" ENSG00000175497 "Dipeptidyl peptidase like 10" Q8N608 2 114442299-115845780 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Asthma "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adrenal gland: 10.1;brain: 20.3;pancreas: 16.3" "Group enriched" "Detected in many" 5 "Astrocytes: 7509.2;Ependymal cells: 9176.2" "Cell type enhanced" "Detected in all" "astrocyte: 10556.8" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 3.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "lung cancer: 4.8;Rhabdoid: 10.6" "Adipose visceral - Mesothelial cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048767 Uncertain NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 53: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 28: Astrocytes - Homeostasis & neuron support" 1 "HPA048767: " "unprognostic (8.17e-2)" "unprognostic (1.70e-2)" "unprognostic (1.17e-3)" "unprognostic (3.06e-3)" "unprognostic (9.45e-2)" "unprognostic (1.10e-1)" "unprognostic (3.09e-1)" "unprognostic (7.96e-2)" "unprognostic (6.31e-2)" "unprognostic (1.04e-1)" "unprognostic (4.24e-2)" DPP3 ENSG00000254986 "Dipeptidyl peptidase 3" Q9NY33 11 66480013-66509657 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 18.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Macrophages, Kidney - Macrophages, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035780, HPA035781" Approved Supported Cytosol NA NA 4900000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 17: Intestine - Digestion" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" 5 Cytosol "HPA035780: , HPA035781: " "unprognostic (1.50e-3)" "unprognostic (3.17e-2)" "unprognostic (3.61e-1)" "unprognostic (2.07e-2)" "unprognostic (2.17e-3)" "unprognostic (7.26e-3)" "unprognostic (3.05e-1)" "unprognostic (2.41e-1)" "unprognostic (2.97e-2)" "potential prognostic unfavorable (1.37e-4)" "unprognostic (3.93e-2)" "unprognostic (2.05e-3)" "unprognostic (2.29e-1)" "potential prognostic unfavorable (4.40e-4)" "unprognostic (2.07e-2)" "unprognostic (2.39e-2)" "potential prognostic unfavorable (9.53e-4)" "unprognostic (2.73e-2)" "unprognostic (2.24e-1)" "unprognostic (2.47e-1)" "unprognostic (3.02e-1)" "unprognostic (2.33e-3)" "unprognostic (7.48e-2)" "unprognostic (4.84e-1)" "unprognostic (4.42e-2)" "unprognostic (1.28e-1)" "unprognostic (1.78e-1)" "unprognostic (4.05e-3)" "unprognostic (7.97e-2)" "unprognostic (2.80e-2)" "unprognostic (1.46e-1)" DPP4 "ADCP2, CD26, DPPIV" ENSG00000197635 "Dipeptidyl peptidase 4" P27487 2 161992245-162074394 "CD markers, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Cell adhesion, Host-virus interaction" "Aminopeptidase, Hydrolase, Protease, Receptor, Serine protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 130.0;parathyroid gland: 146.6;placenta: 126.0;prostate: 100.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 112.8;Cytotrophoblasts: 202.9;Endometrial glandular cells: 162.5;Enterocytes: 347.6;Migrating cytotrophoblasts: 186.2;Neuroendocrine cells: 100.9;Prostatic glandular cells: 367.3;Salivary acinar cells: 190.5;Syncytiotrophoblasts: 238.1" "Cell type enhanced" "Detected in many" "deep-layer corticothalamic and 6b: 38.5;leukocyte: 104.6" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 108.1" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 52.4" "Lineage enriched" "Detected in many" 10 "T-cells: 52.4" "Cancer enhanced" "Detected in many" "Kidney cancer: 54.4" "Adipose visceral - Mesothelial cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB045970, HPA068778, HPA071236" Enhanced "Secreted to blood" Receptor NA NA 643000000 84000000 "Cluster 1: T-cells - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 53: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 51: Secretory epithelial cells - Mixed function" 143 "CAB045970: , HPA068778: , HPA071236: " "unprognostic (1.45e-1)" "unprognostic (1.91e-1)" "unprognostic (1.51e-1)" "unprognostic (1.34e-1)" "unprognostic (1.94e-1)" "unprognostic (1.04e-2)" "unprognostic (2.26e-1)" "unprognostic (8.68e-3)" "unprognostic (1.05e-1)" "unprognostic (2.95e-1)" "validated prognostic favorable (2.36e-9)" "validated prognostic favorable (2.32e-5)" "unprognostic (2.15e-3)" "unprognostic (1.78e-1)" "unprognostic (3.32e-2)" "unprognostic (8.15e-3)" "unprognostic (1.45e-2)" "unprognostic (2.33e-2)" "unprognostic (1.31e-1)" "unprognostic (1.94e-1)" "unprognostic (3.22e-1)" "unprognostic (2.64e-1)" "unprognostic (1.80e-3)" "potential prognostic unfavorable (9.06e-4)" "unprognostic (2.10e-1)" "unprognostic (1.01e-1)" "unprognostic (9.98e-2)" "unprognostic (3.70e-2)" "unprognostic (2.22e-2)" "unprognostic (1.07e-3)" "unprognostic (1.58e-1)" DPP6 "DPL1, DPPX" ENSG00000130226 "Dipeptidyl peptidase like 6" P42658 7 153748133-154894285 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant, Intellectual disability, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 55.9;endometrium 1: 51.4" "Cell type enhanced" "Detected in many" "Bergmann glia: 2537.6;Brain excitatory neurons: 1519.3;Brain inhibitory neurons: 1224.6;Choroid plexus epithelial cells: 3135.4;Ependymal cells: 1743.1;Gonadotrophs: 1250.8;Medullary thymic epithelial cells: 1308.1;Oligodendrocyte progenitor cells: 3309.6;Podocytes: 3210.5;Retinal amacrine cells: 1053.6;Retinal ganglion cells: 2244.3;Sertoli cells: 1585.5" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 13 "Glioblastoma Multiforme (TCGA): 56.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Neuroblastoma: 11.0" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Kidney - Podocytes, Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050509 Enhanced Supported NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 24: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 1 "HPA050509: " "unprognostic (1.49e-1)" "unprognostic (7.28e-2)" "unprognostic (1.93e-1)" "unprognostic (7.78e-2)" "unprognostic (7.85e-2)" "unprognostic (2.41e-1)" "unprognostic (6.75e-3)" "unprognostic (4.96e-2)" "unprognostic (2.96e-1)" "unprognostic (1.38e-3)" "unprognostic (1.06e-1)" "unprognostic (3.31e-3)" "unprognostic (3.17e-1)" DPP7 "DPP2, DPPII" ENSG00000176978 "Dipeptidyl peptidase 7" Q9UHL4 9 137110542-137118309 "Enzymes, Plasma proteins, Predicted secreted proteins" "Aminopeptidase, Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Late spermatids: 1745.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021282, CAB025541, HPA059381" Enhanced Supported "Golgi apparatus,Vesicles" "Secreted - unknown location" Enzyme NA NA 2000000 "Cluster 13: Non-specific - Mitochondria" "Cluster 70: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" Vesicles "Golgi apparatus" "CAB025541: , HPA021282: , HPA059381: " "unprognostic (2.01e-1)" "unprognostic (1.89e-2)" "unprognostic (2.77e-1)" "unprognostic (9.22e-2)" "validated prognostic unfavorable (1.88e-4)" "validated prognostic unfavorable (5.06e-4)" "unprognostic (4.14e-2)" "unprognostic (9.52e-3)" "unprognostic (2.13e-2)" "unprognostic (1.54e-1)" "potential prognostic favorable (1.16e-4)" "unprognostic (1.88e-1)" "unprognostic (2.06e-2)" "unprognostic (2.21e-2)" "unprognostic (1.97e-2)" "unprognostic (5.72e-2)" "unprognostic (2.48e-1)" "unprognostic (6.20e-3)" "unprognostic (2.75e-1)" "unprognostic (4.87e-2)" "unprognostic (2.01e-2)" "potential prognostic favorable (7.78e-4)" "unprognostic (3.42e-1)" "unprognostic (8.25e-3)" "unprognostic (1.78e-3)" "unprognostic (1.37e-1)" "unprognostic (1.42e-1)" "unprognostic (9.26e-2)" "unprognostic (4.59e-2)" "unprognostic (3.89e-1)" "unprognostic (1.50e-3)" DPP8 "DP8, DPRP1, FLJ14920, FLJ20283, MGC26191, MSTP141" ENSG00000074603 "Dipeptidyl peptidase 8" Q6V1X1 15 65442463-65517704 "Enzymes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Aminopeptidase, Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008706 Approved Supported Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" 3 Cytosol "HPA008706: " "unprognostic (3.90e-3)" "unprognostic (1.43e-1)" "unprognostic (3.01e-1)" "unprognostic (3.16e-2)" "unprognostic (3.62e-1)" "unprognostic (1.38e-1)" "unprognostic (6.32e-2)" "unprognostic (5.03e-1)" "unprognostic (2.71e-1)" "unprognostic (2.60e-3)" "validated prognostic favorable (3.31e-4)" "validated prognostic favorable (4.77e-4)" "unprognostic (3.33e-1)" "unprognostic (1.30e-1)" "unprognostic (2.28e-1)" "unprognostic (2.46e-1)" "unprognostic (2.45e-1)" "unprognostic (1.98e-1)" "unprognostic (1.33e-1)" "unprognostic (1.41e-1)" "unprognostic (4.36e-2)" "potential prognostic unfavorable (6.18e-4)" "unprognostic (2.92e-2)" "unprognostic (1.32e-1)" "unprognostic (1.14e-2)" "unprognostic (9.36e-2)" "unprognostic (3.48e-2)" "unprognostic (1.08e-1)" "unprognostic (3.26e-1)" "unprognostic (6.63e-2)" "unprognostic (4.49e-2)" DPP9 ENSG00000142002 "Dipeptidyl peptidase 9" Q86TI2 19 4674341-4724673 "Enzymes, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Protease, Serine protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 98.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036059 Approved Supported Cytosol NA NA 44000 "Cluster 13: Non-specific - Mitochondria" "Cluster 24: Non-specific - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 5 Cytosol "HPA036059: " "unprognostic (2.87e-2)" "unprognostic (4.72e-2)" "unprognostic (2.51e-3)" "unprognostic (1.15e-2)" "unprognostic (2.46e-1)" "unprognostic (2.57e-1)" "unprognostic (1.55e-1)" "unprognostic (2.08e-1)" "unprognostic (1.51e-1)" "potential prognostic unfavorable (8.37e-4)" "unprognostic (1.32e-1)" "unprognostic (7.74e-2)" "unprognostic (2.77e-1)" "unprognostic (8.11e-2)" "unprognostic (2.70e-2)" "unprognostic (5.12e-2)" "unprognostic (2.21e-2)" "unprognostic (8.35e-2)" "unprognostic (1.41e-1)" "unprognostic (5.88e-2)" "unprognostic (9.67e-2)" "unprognostic (2.93e-2)" "potential prognostic unfavorable (1.56e-5)" "unprognostic (3.64e-2)" "unprognostic (3.74e-2)" "unprognostic (6.79e-2)" "unprognostic (2.19e-1)" "unprognostic (1.64e-2)" "unprognostic (1.84e-1)" "unprognostic (2.31e-2)" "unprognostic (2.82e-2)" DPPA2 "CT100, PESCRG1" ENSG00000163530 "Developmental pluripotency associated 2" Q7Z7J5 3 109293788-109316517 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 9 "testis: 3.1" "Group enriched" "Detected in some" 4 "Extravillous trophoblasts: 16.5;Undifferentiated spermatogonia: 32.4" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 24 "Testicular Germ Cell Tumor (TCGA): 44.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "cervical cancer: 3.3;Gastric cancer: 7.2;ovarian cancer: 6.8;Rhabdoid: 2.7;testis cancer: 6.0" "Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA036134 Uncertain Approved Nucleoplasm NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 15: Kidney cancer - Membrane components" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 6 Nucleoplasm "HPA036134: " "unprognostic (4.71e-1)" "unprognostic (4.06e-2)" "unprognostic (3.27e-2)" DPPA3 "Pgc7, Stella" ENSG00000187569 "Developmental pluripotency associated 3" Q6W0C5 12 7711433-7717559 "Predicted intracellular proteins" "Chromatin regulator, Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 1.0;ovary: 3.0;testis: 1.0" "Cell type enriched" "Detected in some" 347 "Oocytes: 902.6" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 855 "Testicular Germ Cell Tumor (TCGA): 594.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 99 "testis cancer: 48.9" "Not detected" "Not detected" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 46: Brainstem - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 41: Oocytes - Oogenesis" 15 "unprognostic (1.34e-1)" DPPA4 FLJ10713 ENSG00000121570 "Developmental pluripotency associated 4" Q7L190 3 109326144-109337546 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.5;lymphoid tissue: 11.6;testis: 3.9" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 30.7;Extravillous trophoblasts: 21.7;Hematopoietic stem cells: 139.7;Innate lymphoid cells: 22.0;Megakaryocyte progenitors: 82.4;Megakaryocyte-Erythroid progenitors: 64.9;Megakaryocytes: 37.1;Migrating cytotrophoblasts: 18.1;pDCs: 26.4;Pituitary stem cells: 28.5;Thymocytes: 52.5;Undifferentiated spermatogonia: 29.5" "Cell type enhanced" "Detected in some" "pericyte: 2.2;vascular associated smooth muscle cell: 1.2" "Cancer enriched" "Detected in single" 266 "Testicular Germ Cell Tumor (TCGA): 123.4" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 12 "plasmacytoid DC: 7.5" "Lineage enriched" "Detected in single" 12 "dendritic cells: 7.5" "Cancer enriched" "Detected in some" 15 "testis cancer: 113.1" "Liver - Hepatocytes, Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB020678, HPA035249, HPA035250" Enhanced Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome,Cytosol" Yes NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 34: Testis cancer - Unknown function" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 33 "Nucleoli, Nucleoli rim" "Nucleoplasm, Mitotic chromosome, Cytosol" "CAB020678: , HPA035249: , HPA035250: " "unprognostic (1.26e-2)" "unprognostic (3.31e-2)" DPPA5 Esg1 ENSG00000203909 "Developmental pluripotency associated 5" A6NC42 6 73353063-73354276 "Predicted intracellular proteins" "Developmental protein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "testis: 2.0" "Cell type enriched" "Detected in some" 68 "Oocytes: 207.2" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 1949 "Testicular Germ Cell Tumor (TCGA): 539.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "testis cancer: 6.3" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA055016, HPA064505" Uncertain Uncertain "Cell Junctions" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 41: Oocytes - Oogenesis" "Cell Junctions" "HPA055016: , HPA064505: " "unprognostic (1.35e-1)" DPRX ENSG00000204595 "Divergent-paired related homeobox" A6NFQ7 19 53631999-53637014 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "placenta: 1.0;skeletal muscle: 1.0" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 1.5;Early spermatids: 1.2;Late spermatids: 2.7;Migrating cytotrophoblasts: 1.9;Oocytes: 4.6;pDCs: 1.3;Syncytiotrophoblasts: 7.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 32 "Testicular Germ Cell Tumor (TCGA): 2.6;Thyroid Carcinoma (TCGA): 7.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA043682 Uncertain NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" "HPA043682: " "unprognostic (1.16e-1)" "unprognostic (1.10e-1)" DPT ENSG00000143196 Dermatopontin Q07507 1 168695468-168729206 "Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 431.1" "Cell type enhanced" "Detected in some" "Fibro-adipogenic progenitors: 24.9;Fibroblasts: 135.2;Hepatic stellate cells: 71.0;Leydig cells: 103.5;Peritubular myoid cells: 83.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 3.0;thyroid cancer: 6.0" "Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Minor Salivary Gland - Fibroblasts, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in single" "Region enhanced" "Detected in single" "midbrain: 1.4" HPA065548 Approved Vesicles "Secreted to extracellular matrix" "Cell adhesion" NA NA 3500000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 53: Neurons - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" Vesicles "HPA065548: " "unprognostic (3.75e-1)" "unprognostic (2.29e-1)" "unprognostic (6.34e-2)" "unprognostic (7.34e-3)" "unprognostic (3.73e-2)" "unprognostic (4.96e-2)" "unprognostic (9.90e-2)" "unprognostic (1.02e-1)" "unprognostic (2.19e-3)" "unprognostic (2.06e-2)" "unprognostic (1.15e-1)" "unprognostic (8.81e-2)" "unprognostic (5.91e-2)" "potential prognostic favorable (3.08e-4)" "unprognostic (1.46e-1)" "unprognostic (2.08e-2)" "unprognostic (6.71e-2)" "unprognostic (1.84e-1)" "unprognostic (1.97e-3)" "unprognostic (1.44e-2)" "unprognostic (4.12e-2)" "unprognostic (7.86e-2)" "unprognostic (8.47e-3)" "unprognostic (1.22e-1)" "unprognostic (7.79e-3)" "unprognostic (2.87e-1)" "unprognostic (7.01e-3)" "unprognostic (5.01e-2)" "unprognostic (7.08e-2)" "unprognostic (1.58e-2)" DPY19L1 KIAA0877 ENSG00000173852 "Dpy-19 like C-mannosyltransferase 1" Q2PZI1 7 34927292-35038271 "Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 207.7;Early spermatids: 287.2;Platelets: 222.7;Sertoli cells: 160.1" "Cell type enhanced" "Detected in all" "deep-layer near-projecting: 375.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Skin - Endothelial cells, Spleen - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059139 Uncertain Approved Vesicles NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 81: Alveolar cells - Lung function" 15 Vesicles "HPA059139: " "unprognostic (2.18e-1)" "unprognostic (8.12e-2)" "unprognostic (6.76e-2)" "unprognostic (4.31e-3)" "unprognostic (5.43e-2)" "unprognostic (4.51e-3)" "unprognostic (3.87e-2)" "potential prognostic unfavorable (3.63e-4)" "unprognostic (2.01e-2)" "unprognostic (1.09e-1)" "unprognostic (2.53e-2)" "unprognostic (1.67e-1)" "unprognostic (3.56e-2)" "potential prognostic unfavorable (2.40e-4)" "unprognostic (1.78e-3)" "unprognostic (1.39e-3)" "unprognostic (2.36e-3)" "unprognostic (3.93e-1)" "unprognostic (3.02e-2)" "unprognostic (7.77e-2)" "unprognostic (1.84e-1)" "unprognostic (2.36e-3)" "unprognostic (3.63e-3)" "unprognostic (2.61e-1)" "unprognostic (1.72e-2)" "unprognostic (1.07e-1)" "unprognostic (8.43e-2)" "unprognostic (2.17e-1)" "unprognostic (5.15e-2)" "unprognostic (4.01e-1)" "unprognostic (9.90e-2)" DPY19L2 "FLJ32949, SPATA34" ENSG00000177990 "Dpy-19 like 2" Q6NUT2 12 63558913-63668939 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Spermatogenesis" "Developmental protein, Glycosyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 78.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 519.9;Distal convoluted tubule cells: 234.2;Ependymal cells: 176.5;Late spermatids: 174.3;Oligodendrocyte progenitor cells: 161.4;Pituitary stem cells: 192.8;Renal collecting duct intercalated cells: 335.1;Renal connecting tubule cells: 455.5;Somatotrophs: 163.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "MAIT T-cell: 1.0" "Lineage enriched" "Detected in single" 5 "T-cells: 1.0" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skin - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA071264, HPA078305" Enhanced Approved Nucleoplasm,Mitochondria Yes No "Cluster 24: Non-specific - Transcription" "Cluster 35: Non-specific - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" Mitochondria Nucleoplasm "HPA071264: , HPA078305: " "unprognostic (8.04e-2)" "unprognostic (3.34e-1)" "unprognostic (8.70e-2)" "unprognostic (6.15e-2)" "unprognostic (1.28e-1)" "unprognostic (4.73e-1)" "unprognostic (8.12e-2)" "unprognostic (1.01e-3)" "unprognostic (1.54e-2)" "unprognostic (4.16e-2)" "unprognostic (1.36e-1)" "unprognostic (1.23e-2)" "potential prognostic favorable (7.31e-4)" "unprognostic (3.66e-3)" "unprognostic (1.45e-1)" "unprognostic (1.92e-2)" "unprognostic (2.79e-1)" "unprognostic (2.98e-2)" "unprognostic (1.15e-1)" "potential prognostic unfavorable (4.42e-4)" "potential prognostic unfavorable (7.63e-4)" DPY19L3 ENSG00000178904 "Dpy-19 like C-mannosyltransferase 3" Q6ZPD9 19 32405543-32485895 "Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bergmann glia: 250.7;Podocytes: 202.9;Retinal horizontal cells: 296.5;Somatotrophs: 161.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008325 Approved Approved Microtubules NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 65: Brain - Transcription" "Cluster 29: Forebrain - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 48: Neutrophils - Phagocytosis & degranulation" Microtubules "HPA008325: " "unprognostic (5.23e-2)" "unprognostic (5.51e-2)" "unprognostic (1.28e-1)" "unprognostic (1.08e-1)" "unprognostic (1.26e-1)" "unprognostic (2.27e-2)" "unprognostic (3.72e-2)" "unprognostic (6.54e-2)" "unprognostic (1.06e-3)" "unprognostic (4.58e-2)" "potential prognostic favorable (6.24e-6)" "unprognostic (2.26e-1)" "unprognostic (1.41e-1)" "unprognostic (7.41e-2)" "unprognostic (1.21e-1)" "unprognostic (2.57e-1)" "unprognostic (5.77e-2)" "unprognostic (9.54e-2)" "unprognostic (6.02e-3)" "unprognostic (1.88e-1)" "unprognostic (1.42e-1)" "unprognostic (8.65e-3)" "unprognostic (2.97e-3)" "unprognostic (3.71e-1)" "unprognostic (1.30e-1)" "unprognostic (9.96e-2)" "unprognostic (1.65e-2)" "unprognostic (2.97e-2)" "unprognostic (2.13e-1)" "unprognostic (1.37e-1)" "unprognostic (1.80e-2)" DPY19L4 ENSG00000156162 "Dpy-19 like 4" Q7Z388 8 94719703-94793836 "Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Parietal cells: 122.0;Sertoli cells: 130.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024780 Approved Approved Vesicles NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 8 Vesicles "HPA024780: " "unprognostic (3.11e-2)" "unprognostic (1.02e-2)" "unprognostic (1.96e-2)" "potential prognostic unfavorable (1.01e-4)" "unprognostic (1.48e-1)" "unprognostic (5.04e-2)" "unprognostic (2.51e-1)" "unprognostic (4.60e-2)" "unprognostic (2.11e-1)" "unprognostic (6.63e-2)" "potential prognostic favorable (3.16e-5)" "unprognostic (2.38e-3)" "unprognostic (3.56e-1)" "unprognostic (6.99e-3)" "unprognostic (4.50e-3)" "unprognostic (2.47e-3)" "unprognostic (2.20e-1)" "unprognostic (2.06e-1)" "unprognostic (1.32e-1)" "unprognostic (1.26e-3)" "unprognostic (2.47e-2)" "unprognostic (8.39e-2)" "potential prognostic unfavorable (8.23e-4)" "unprognostic (8.16e-2)" "unprognostic (1.96e-1)" "unprognostic (2.02e-1)" "unprognostic (1.75e-2)" "unprognostic (2.71e-2)" "unprognostic (3.54e-1)" "unprognostic (1.13e-2)" "unprognostic (1.29e-1)" DPY30 "Cps25, HDPY-30, Saf19" ENSG00000162961 "Dpy-30 histone methyltransferase complex regulatory subunit" Q9C005 2 31867809-32039805 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 358.5;Epididymal efferent duct ciliated cells: 397.0;Esophageal apical cells: 465.2;Fallopian tube ciliated cells: 455.8;Oocytes: 428.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043761 Supported Supported "Nucleoplasm,Golgi apparatus" NA NA 13000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 76: Non-specific - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 107: Ciliated cells - Cilia assembly & function" 54 Nucleoplasm "Golgi apparatus" "HPA043761: " "unprognostic (5.75e-2)" "unprognostic (8.21e-2)" "unprognostic (6.23e-2)" "unprognostic (1.53e-2)" "unprognostic (2.88e-1)" "unprognostic (2.86e-1)" "unprognostic (1.13e-1)" "unprognostic (4.62e-2)" "unprognostic (2.58e-3)" "unprognostic (3.97e-3)" "unprognostic (6.53e-3)" "unprognostic (1.86e-1)" "unprognostic (3.13e-3)" "validated prognostic unfavorable (1.31e-5)" "validated prognostic unfavorable (1.82e-5)" "unprognostic (2.38e-2)" "unprognostic (1.52e-1)" "unprognostic (1.52e-2)" "unprognostic (5.60e-2)" "unprognostic (1.19e-3)" "unprognostic (6.71e-2)" "unprognostic (2.78e-3)" "unprognostic (1.87e-3)" "unprognostic (9.50e-2)" "unprognostic (2.98e-2)" "unprognostic (1.09e-1)" "unprognostic (1.02e-1)" "unprognostic (1.63e-1)" "unprognostic (1.00e-1)" "unprognostic (4.13e-2)" "unprognostic (2.09e-2)" DPYD "DHPDHase, DPD" ENSG00000188641 "Dihydropyrimidine dehydrogenase" Q12882 1 97077743-97995000 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 64.0" "Cell type enhanced" "Detected in many" "Corticotrophs: 1559.1;Kupffer cells: 1295.5;Monocyte progenitors: 1635.3;monocytes: 2567.4;Neutrophil progenitors: 2214.0;Neutrophils: 6341.9;Oligodendrocytes: 1526.4" "Cell type enhanced" "Detected in all" "oligodendrocyte: 2324.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Liver - Hepatocytes, Prostate - Fibroblasts, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033241, HPA045210" Uncertain NA NA 1500000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 11: White matter - Signal transduction" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 24: Neutrophils - Innate immunity signal integration" 4 "CAB033241: , HPA045210: " "unprognostic (6.22e-2)" "unprognostic (2.32e-2)" "unprognostic (1.50e-1)" "unprognostic (3.09e-1)" "unprognostic (1.30e-1)" "unprognostic (1.98e-1)" "unprognostic (2.71e-2)" "unprognostic (1.51e-2)" "unprognostic (8.94e-2)" "unprognostic (1.55e-2)" "unprognostic (2.35e-3)" "unprognostic (2.47e-1)" "unprognostic (3.20e-2)" "unprognostic (2.23e-1)" "unprognostic (5.42e-2)" "unprognostic (2.54e-1)" "unprognostic (2.26e-3)" "unprognostic (9.10e-3)" "potential prognostic unfavorable (1.27e-4)" "unprognostic (7.89e-2)" "unprognostic (1.62e-1)" "potential prognostic unfavorable (5.61e-4)" "unprognostic (3.58e-2)" "unprognostic (1.21e-1)" "unprognostic (8.01e-2)" "unprognostic (9.39e-2)" "unprognostic (1.12e-1)" "unprognostic (6.47e-2)" "unprognostic (8.87e-3)" "unprognostic (2.92e-1)" "unprognostic (1.93e-1)" DPYS DHPase ENSG00000147647 Dihydropyrimidinase Q14117 8 104330324-104467055 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 40 "kidney: 186.1;liver: 446.6" "Group enriched" "Detected in many" 8 "Hepatocytes: 686.5;Medullary thymic epithelial cells: 559.3;Mesothelial cells: 321.4;Proximal tubule cells: 389.5" "Cell type enhanced" "Detected in many" "thalamic excitatory: 106.6" "Cancer enhanced" "Detected in some" "Liver Hepatocellular Carcinoma (TCGA): 126.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Rhabdoid: 1.2" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA024785, HPA070814" Enhanced NA NA 750000 "Cluster 16: Liver & Kidney - Metabolism" "Cluster 38: Sub-cortical - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 88: Proximal tubular cells - Transmembrane transport" 10 "HPA024785: , HPA070814: " "potential prognostic favorable (4.90e-6)" "unprognostic (3.55e-3)" "unprognostic (4.78e-2)" "unprognostic (1.43e-3)" "potential prognostic favorable (5.00e-4)" "unprognostic (2.18e-3)" "unprognostic (9.54e-2)" "unprognostic (4.75e-1)" DPYSL2 "CRMP2, DHPRP2, DRP-2, DRP2" ENSG00000092964 "Dihydropyrimidinase like 2" Q16555 8 26514031-26658178 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 231.1" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 319.2;Kupffer cells: 326.9;Oligodendrocytes: 588.8;Other brain neurons: 352.3;Retinal amacrine cells: 317.3;Retinal ganglion cells: 367.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 215.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 65.8;intermediate monocyte: 74.5;myeloid DC: 71.2;non-classical monocyte: 49.0;plasmacytoid DC: 42.3" "Group enriched" "Detected in all" 5 "dendritic cells: 71.2;monocytes: 74.5" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Prostate - Fibroblasts, Skeletal muscle - Endothelial cells, Thyroid gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002381, CAB018719" Supported Supported "Plasma membrane,Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Cytosol" Yes NA 2500000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 80: Oligodendrocytes - Myelination" 38 "Microtubules, Cytosol" "Plasma membrane, Cytokinetic bridge, Mitotic spindle, Primary cilium" "CAB018719: , HPA002381: " "unprognostic (1.85e-2)" "unprognostic (1.43e-1)" "unprognostic (1.20e-2)" "unprognostic (1.08e-2)" "unprognostic (1.91e-1)" "potential prognostic unfavorable (1.11e-4)" "unprognostic (1.23e-1)" "unprognostic (3.09e-2)" "unprognostic (2.27e-2)" "unprognostic (1.30e-1)" "potential prognostic favorable (6.01e-6)" "unprognostic (8.88e-3)" "unprognostic (3.45e-2)" "unprognostic (8.42e-2)" "unprognostic (4.37e-2)" "unprognostic (4.32e-3)" "unprognostic (1.28e-1)" "unprognostic (5.66e-3)" "unprognostic (2.36e-1)" "unprognostic (2.30e-1)" "unprognostic (1.12e-3)" "unprognostic (3.32e-2)" "unprognostic (3.96e-2)" "unprognostic (6.48e-2)" "unprognostic (3.15e-1)" "unprognostic (1.06e-1)" "unprognostic (2.08e-1)" "unprognostic (2.44e-2)" "unprognostic (2.75e-1)" "unprognostic (3.59e-3)" "unprognostic (5.31e-2)" DPYSL3 "CRMP4, DRP-3, ULIP" ENSG00000113657 "Dihydropyrimidinase like 3" Q14195 5 147390808-147510068 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 1140.6;Ependymal cells: 416.4;Fibro-adipogenic progenitors: 261.0;Granulosa cells: 449.3;Ovarian stromal cells: 260.3;Peritubular myoid cells: 329.3;Prostatic glandular cells: 233.5;Rod photoreceptor cells: 526.0;Smooth muscle cells: 351.1;Tuft cells: 564.9" "Cell type enhanced" "Detected in many" "astrocyte: 336.9;ependymal cell: 469.3" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 228.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Prostate - Smooth muscle cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010948 Approved Approved Cytosol NA NA 680000 "Cluster 74: Non-specific - Signal transduction" "Cluster 39: Astrocytes - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 79: Photoreceptor cells - Phototransduction" 9 Cytosol "HPA010948: " "unprognostic (4.16e-2)" "unprognostic (1.11e-1)" "unprognostic (3.26e-2)" "unprognostic (1.27e-1)" "unprognostic (6.29e-2)" "unprognostic (1.35e-1)" "unprognostic (8.69e-2)" "unprognostic (2.53e-1)" "unprognostic (1.34e-1)" "unprognostic (2.14e-2)" "unprognostic (1.14e-2)" "unprognostic (2.43e-2)" "potential prognostic unfavorable (6.69e-6)" "unprognostic (7.43e-2)" "unprognostic (3.74e-2)" "unprognostic (8.71e-2)" "unprognostic (1.10e-2)" "unprognostic (4.49e-1)" "unprognostic (2.09e-1)" "unprognostic (1.39e-2)" "unprognostic (1.62e-2)" "unprognostic (3.74e-1)" "unprognostic (1.47e-1)" "unprognostic (1.43e-1)" "unprognostic (5.02e-3)" "unprognostic (3.14e-2)" "unprognostic (1.18e-1)" "unprognostic (9.15e-3)" "unprognostic (2.09e-1)" "unprognostic (8.28e-2)" "unprognostic (1.45e-1)" DPYSL4 "CRMP3, DRP-4, ULIP4" ENSG00000151640 "Dihydropyrimidinase like 4" O14531 10 132186948-132205759 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.8;heart muscle: 33.0" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 13.8;Brain inhibitory neurons: 18.9;Cone photoreceptor cells: 62.1;Late primary spermatocytes: 11.6;Late spermatids: 14.5;Oligodendrocyte progenitor cells: 17.1;Oligodendrocytes: 17.1;Other brain neurons: 15.4;Retinal amacrine cells: 49.6;Retinal bipolar cells: 42.8;Retinal horizontal cells: 26.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 27.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 63.8" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049066 Approved Approved Vesicles,Mitochondria NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 16 Mitochondria Vesicles "HPA049066: " "potential prognostic unfavorable (2.72e-4)" "unprognostic (1.14e-1)" "unprognostic (1.30e-1)" "unprognostic (2.28e-2)" "unprognostic (3.46e-1)" "potential prognostic favorable (2.63e-4)" "unprognostic (4.69e-2)" "unprognostic (1.59e-1)" "unprognostic (5.99e-2)" "unprognostic (8.63e-2)" "unprognostic (1.32e-1)" "unprognostic (2.53e-1)" "unprognostic (3.13e-2)" "unprognostic (1.39e-1)" "unprognostic (4.48e-2)" "unprognostic (6.08e-2)" "unprognostic (8.40e-2)" "unprognostic (1.02e-2)" "unprognostic (2.18e-1)" "unprognostic (2.07e-2)" "unprognostic (1.15e-1)" DPYSL5 "CRAM, CRMP-5, CRMP5, CV2, Ulip6" ENSG00000157851 "Dihydropyrimidinase like 5" Q9BPU6 2 26847747-26950351 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "brain: 128.7" "Cell type enhanced" "Detected in some" "Bergmann glia: 139.6;Brain inhibitory neurons: 124.5;Cone photoreceptor cells: 364.3;Corticotrophs: 73.0;Lactotrophs: 95.1;Late spermatids: 254.0;Oligodendrocytes: 327.7;Other brain neurons: 84.0;Retinal ganglion cells: 127.5;Thyrotrophs: 90.1" "Cell type enhanced" "Detected in all" "oligodendrocyte: 593.5" "Group enriched" "Detected in some" 16 "Glioblastoma Multiforme (TCGA): 38.9;Testicular Germ Cell Tumor (TCGA): 18.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Bone cancer: 32.9;lung cancer: 23.5;Neuroblastoma: 77.2" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034544, HPA072387" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 80: Oligodendrocytes - Myelination" 27 Nucleoplasm Cytosol "HPA034544: , HPA072387: " "unprognostic (4.34e-1)" "unprognostic (1.35e-2)" "unprognostic (2.75e-1)" "unprognostic (4.71e-2)" "unprognostic (2.15e-1)" "unprognostic (4.03e-2)" DQX1 FLJ23757 ENSG00000144045 "DEAQ-box RNA dependent ATPase 1" Q8TE96 2 74518131-74526281 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 15.4" "Cell type enhanced" "Detected in some" "Colonocytes: 20.0;Enteric stem cells: 9.5;Enteric transient amplifying cells: 13.6;Enterocytes: 44.2;Esophageal apical cells: 7.7;Esophageal suprabasal cells: 6.6;Foveolar cells: 20.0;Goblet cells: 20.6;Paneth cells: 7.7;Tuft cells: 23.1" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 2.5" "Adrenal gland - Adrenal medulla cells, Colon - Colon enterocytes, Prostate - Urothelial cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA039158, HPA046763" Enhanced Approved "Nucleoli fibrillar center" NA NA "Cluster 77: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 1: Enterocytes - Absorption and Digestion" "Nucleoli fibrillar center" "HPA039158: , HPA046763: " "unprognostic (5.04e-1)" "unprognostic (1.57e-2)" "unprognostic (1.87e-2)" "unprognostic (7.28e-2)" "unprognostic (4.46e-2)" "unprognostic (1.74e-2)" "unprognostic (2.75e-3)" "unprognostic (1.87e-2)" "unprognostic (1.67e-2)" "unprognostic (4.67e-3)" "unprognostic (3.06e-2)" "unprognostic (6.95e-2)" "unprognostic (4.30e-2)" DR1 "NC2-BETA, NC2B, NCB2" ENSG00000117505 "Down-regulator of transcription 1" Q01658 1 93345907-93369493 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 283.0;Megakaryocytes: 185.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050785, HPA055308" Enhanced Supported Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 39: Testis - Nuclear processes" "Cluster 21: Non-specific - Metabolism" "Cluster 37: Non-specific - mRNA processing" "Cluster 26: Keratinocytes - Keratinization" 75 Nucleoplasm "HPA050785: , HPA055308: " "unprognostic (1.69e-1)" "unprognostic (2.06e-1)" "unprognostic (1.78e-2)" "unprognostic (4.15e-2)" "unprognostic (1.72e-2)" "unprognostic (1.93e-2)" "unprognostic (8.64e-2)" "unprognostic (1.18e-1)" "unprognostic (9.69e-2)" "unprognostic (3.76e-3)" "potential prognostic favorable (2.22e-6)" "unprognostic (6.97e-3)" "unprognostic (2.95e-2)" "potential prognostic unfavorable (4.52e-9)" "unprognostic (8.31e-3)" "unprognostic (1.19e-2)" "unprognostic (4.74e-3)" "unprognostic (1.73e-1)" "unprognostic (2.49e-1)" "unprognostic (3.13e-1)" "unprognostic (2.32e-2)" "potential prognostic unfavorable (1.32e-4)" "unprognostic (2.81e-1)" "unprognostic (4.62e-2)" "unprognostic (1.65e-1)" "unprognostic (6.75e-2)" "unprognostic (7.71e-2)" "unprognostic (3.13e-1)" "unprognostic (1.52e-1)" "unprognostic (4.46e-2)" "unprognostic (3.24e-1)" DRAM1 "DRAM, FLJ11259" ENSG00000136048 "DNA damage regulated autophagy modulator 1" Q8N682 12 101877580-102012130 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Autophagy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 88.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 464.9;Early spermatids: 268.6;monocytes: 246.7;Neutrophil progenitors: 190.9;Neutrophils: 424.2;Transitional alveolar cells: 269.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 13: Lung - Secretion" "Cluster 31: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 6 "unprognostic (1.68e-1)" "unprognostic (1.32e-1)" "unprognostic (1.46e-1)" "unprognostic (2.73e-1)" "unprognostic (1.03e-1)" "unprognostic (3.65e-2)" "unprognostic (4.02e-2)" "potential prognostic unfavorable (1.16e-5)" "unprognostic (2.59e-3)" "unprognostic (3.55e-1)" "potential prognostic favorable (3.85e-4)" "unprognostic (8.09e-3)" "unprognostic (2.33e-2)" "unprognostic (1.58e-3)" "unprognostic (1.21e-2)" "unprognostic (8.40e-3)" "unprognostic (3.96e-1)" "unprognostic (1.05e-2)" "unprognostic (1.64e-1)" "unprognostic (6.23e-2)" "unprognostic (4.54e-1)" "unprognostic (3.51e-2)" "unprognostic (2.19e-1)" "unprognostic (2.08e-1)" "unprognostic (1.28e-1)" "potential prognostic favorable (4.73e-4)" "unprognostic (2.53e-1)" "unprognostic (4.95e-2)" "unprognostic (3.68e-3)" "unprognostic (1.44e-1)" "unprognostic (1.62e-1)" DRAM2 "MGC54289, PRO180, RP5-1180E21.1, TMEM77, WWFQ154" ENSG00000156171 "DNA damage regulated autophagy modulator 2" Q6UX65 1 111117163-111140203 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Apoptosis, Autophagy" "Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "B-cells: 196.7;Hofbauer cells: 228.7;Kupffer cells: 235.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018036, HPA061701" Supported Enhanced "Golgi apparatus,Vesicles" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 25: Non-specific - Ribosome" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 1 "Golgi apparatus, Vesicles" "HPA018036: , HPA061701: " "unprognostic (2.25e-1)" "unprognostic (2.27e-1)" "unprognostic (2.87e-1)" "unprognostic (2.57e-1)" "potential prognostic favorable (1.58e-4)" "unprognostic (2.29e-1)" "unprognostic (4.26e-2)" "unprognostic (5.52e-2)" "unprognostic (1.03e-2)" "unprognostic (3.79e-3)" "unprognostic (2.20e-2)" "unprognostic (3.92e-1)" "unprognostic (4.54e-2)" "potential prognostic unfavorable (2.86e-6)" "unprognostic (1.35e-3)" "unprognostic (2.51e-1)" "unprognostic (8.36e-2)" "unprognostic (3.71e-3)" "unprognostic (1.25e-1)" "unprognostic (2.59e-1)" "unprognostic (4.87e-2)" "unprognostic (7.07e-3)" "unprognostic (1.11e-1)" "unprognostic (1.16e-1)" "unprognostic (3.04e-2)" "unprognostic (4.41e-2)" "unprognostic (6.38e-3)" "unprognostic (2.29e-1)" "unprognostic (1.24e-1)" "unprognostic (3.09e-1)" "unprognostic (1.26e-2)" DRAP1 NC2-alpha ENSG00000175550 "DR1 associated protein 1" Q14919 11 65919274-65921563 "Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 601.0;Esophageal apical cells: 426.3;Esophageal suprabasal cells: 472.9;Suprabasal keratinocytes: 791.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Stomach - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006790 Uncertain Approved Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 26: Keratinocytes - Keratinization" 29 Cytosol "HPA006790: " "unprognostic (1.10e-2)" "unprognostic (2.00e-2)" "unprognostic (5.12e-2)" "unprognostic (4.73e-2)" "unprognostic (1.00e-1)" "unprognostic (1.77e-1)" "unprognostic (8.31e-3)" "unprognostic (4.21e-2)" "unprognostic (2.87e-3)" "unprognostic (4.01e-2)" "validated prognostic unfavorable (8.26e-4)" "validated prognostic unfavorable (7.94e-4)" "unprognostic (2.33e-2)" "potential prognostic unfavorable (6.42e-5)" "unprognostic (4.83e-2)" "unprognostic (2.35e-2)" "unprognostic (9.32e-3)" "unprognostic (1.71e-1)" "unprognostic (2.78e-2)" "unprognostic (2.12e-1)" "unprognostic (2.68e-2)" "unprognostic (3.66e-2)" "unprognostic (1.99e-2)" "unprognostic (1.96e-2)" "unprognostic (8.64e-2)" "unprognostic (1.85e-1)" "unprognostic (3.64e-2)" "unprognostic (2.08e-2)" "unprognostic (2.29e-1)" "unprognostic (3.04e-2)" "unprognostic (3.76e-2)" DRAXIN "C1orf187, FLJ34999, Neucrin" ENSG00000162490 "Dorsal inhibitory axon guidance protein" Q8NBI3 1 11691710-11725857 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.0" "Cell type enhanced" "Detected in some" "Brain inhibitory neurons: 3.4;Late spermatids: 3.1;Neutrophil progenitors: 2.6;NK-cells: 15.7;pDCs: 2.6;T-cells: 4.3;Undifferentiated spermatogonia: 3.5" "Cell type enhanced" "Detected in many" "eccentric medium spiny neuron: 15.1" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 7.9;Testicular Germ Cell Tumor (TCGA): 5.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.4" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.4" "Cancer enhanced" "Detected in some" "testis cancer: 4.2" "Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA014302 Uncertain "Secreted in brain" "Developmental protein" NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 34: Non-specific - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 1 "HPA014302: " "unprognostic (1.87e-1)" "unprognostic (2.83e-1)" "unprognostic (1.04e-1)" "unprognostic (1.90e-1)" "unprognostic (1.85e-1)" "unprognostic (1.38e-1)" "unprognostic (6.07e-2)" DRC1 "C2orf39, CCDC164, CILD21, FLJ32660, MGC16372" ENSG00000157856 "Dynein regulatory complex subunit 1" Q96MC2 2 26401920-26456711 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "choroid plexus: 23.0;fallopian tube: 36.9;testis: 19.6" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 204.2;Early spermatids: 165.1;Endometrial ciliated cells: 218.8;Ependymal cells: 306.0;Epididymal efferent duct ciliated cells: 165.8;Fallopian tube ciliated cells: 293.7;Late primary spermatocytes: 116.8;Late spermatids: 499.1;Respiratory ciliated cells: 383.6" "Group enriched" "Detected in many" 13 "choroid plexus epithelial cell: 151.4;ependymal cell: 321.6" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 7.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 89 "neutrophil: 8.9" "Lineage enriched" "Detected in single" 89 "granulocytes: 8.9" "Cancer enhanced" "Detected in single" "Bile duct cancer: 2.9" "Colon - Enteric glia cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "midbrain: 10.3" HPA051247 Approved "Nucleoplasm,Primary cilium transition zone" NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" "Nucleoplasm, Primary cilium transition zone" "HPA051247: " "unprognostic (9.58e-2)" "unprognostic (1.94e-3)" "potential prognostic unfavorable (1.67e-6)" "unprognostic (7.36e-2)" "unprognostic (1.37e-1)" "unprognostic (3.17e-1)" "unprognostic (2.01e-3)" "unprognostic (6.32e-2)" DRC3 "CFAP134, DKFZP586M1120, LRRC48" ENSG00000171962 "Dynein regulatory complex subunit 3" Q9H069 17 17972813-18016889 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 25.1;fallopian tube: 57.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 84.9;Endometrial ciliated cells: 206.1;Ependymal cells: 311.1;Epididymal efferent duct ciliated cells: 238.8;Fallopian tube ciliated cells: 354.4;Respiratory ciliated cells: 459.3" "Cell type enriched" "Detected in all" 4 "ependymal cell: 340.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells, Spleen - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036040, HPA036041" Approved Approved "Mid piece,Principal piece,End piece" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" "Mid piece, Principal piece, End piece" "HPA036040: , HPA036041: " "unprognostic (1.72e-2)" "unprognostic (3.11e-3)" "unprognostic (2.62e-2)" "unprognostic (1.58e-1)" "potential prognostic favorable (2.53e-6)" "unprognostic (3.15e-3)" "unprognostic (1.49e-3)" "unprognostic (7.17e-2)" "unprognostic (1.57e-2)" "unprognostic (2.84e-1)" "unprognostic (2.84e-1)" "unprognostic (1.51e-1)" "unprognostic (8.15e-2)" "unprognostic (3.54e-3)" "unprognostic (5.53e-3)" "unprognostic (2.14e-1)" "unprognostic (1.51e-1)" "unprognostic (1.68e-1)" "unprognostic (2.05e-1)" DRC7 "C16orf50, CCDC135, CFAP50, DKFZp434I099, FAP50" ENSG00000159625 "Dynein regulatory complex subunit 7" Q8IY82 16 57694793-57731805 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "choroid plexus: 11.7;fallopian tube: 19.8;testis: 43.1" "Group enriched" "Detected in some" 6 "Early spermatids: 110.7;Endometrial ciliated cells: 54.4;Ependymal cells: 105.0;Epididymal efferent duct ciliated cells: 53.3;Fallopian tube ciliated cells: 74.0;Late primary spermatocytes: 179.0;Late spermatids: 206.8;Respiratory ciliated cells: 138.3" "Cell type enriched" "Detected in many" 7 "ependymal cell: 120.4" "Group enriched" "Detected in some" 4 "Kidney Renal Papillary Cell Carcinoma (TCGA): 10.7;Uterine Corpus Endometrial Carcinoma (TCGA): 8.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 8 "basophil: 10.9" "Lineage enriched" "Detected in single" 43 "granulocytes: 10.9" "Cancer enhanced" "Detected in some" "Bile duct cancer: 2.0" "Adipose visceral - Mesothelial cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" 4 "unprognostic (4.04e-2)" "unprognostic (7.83e-2)" "unprognostic (1.54e-2)" "unprognostic (1.40e-3)" "unprognostic (1.97e-1)" "unprognostic (7.36e-3)" "unprognostic (2.06e-1)" "unprognostic (3.47e-2)" "unprognostic (1.01e-2)" "unprognostic (2.85e-2)" DRD1 ENSG00000184845 "Dopamine receptor D1" P21728 5 175440036-175444182 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 16 "brain: 26.0;retina: 7.8" "Group enriched" "Detected in some" 4 "Brain inhibitory neurons: 31.5;Ependymal cells: 18.2;Retinal amacrine cells: 33.8;Retinal bipolar cells: 21.0;Retinal horizontal cells: 32.1" "Group enriched" "Detected in many" 4 "eccentric medium spiny neuron: 118.5;medium spiny neuron: 74.5" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "basal ganglia: 46.6;cerebral cortex: 12.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 1.1;Bone cancer: 1.6" "Breast - Endothelial cells, Kidney - Fibroblasts" "Region enriched" "Detected in many" 9 "basal ganglia: 164.5" "Region enriched" "Detected in many" 13 "basal ganglia: 119.1" "HPA013393, HPA017304" Supported Approved "Plasma membrane,Cytosol" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Neurons - Synaptic function & neurogenesis" 11 "Plasma membrane" Cytosol "HPA013393: , HPA017304: " "unprognostic (4.46e-1)" "unprognostic (1.71e-1)" "unprognostic (6.72e-3)" "unprognostic (2.58e-1)" DRD2 ENSG00000149295 "Dopamine receptor D2" P14416 11 113409605-113475691 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 62.0;pituitary gland: 56.6" "Cell type enhanced" "Detected in some" "Brain inhibitory neurons: 51.3;Lactotrophs: 356.3;Other brain neurons: 27.3;Retinal horizontal cells: 162.3;Thyrotrophs: 87.6" "Cell type enriched" "Detected in many" 9 "medium spiny neuron: 148.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "basal ganglia: 163.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 7.6" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pituitary gland - Lactotropes, Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in many" 10 "basal ganglia: 205.4" "Region enriched" "Detected in many" 4 "basal ganglia: 192.0" "HPA015139, HPA015691" Supported Supported NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 19 "HPA015139: , HPA015691: " "unprognostic (3.30e-1)" "unprognostic (2.17e-1)" "unprognostic (7.41e-2)" "unprognostic (6.47e-2)" "unprognostic (1.62e-2)" "unprognostic (4.03e-2)" "unprognostic (9.51e-2)" "unprognostic (9.94e-2)" "unprognostic (3.06e-1)" "unprognostic (3.16e-3)" "unprognostic (1.36e-1)" "unprognostic (1.02e-1)" DRD3 ENSG00000151577 "Dopamine receptor D3" P35462 3 114127580-114199407 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets, Schizophrenia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 8 "brain: 5.2" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 5.6;Brain inhibitory neurons: 26.0;Early spermatids: 38.8;Late spermatids: 70.7;Other brain neurons: 11.6" "Group enriched" "Detected in many" 4 "mammillary body: 106.0;medium spiny neuron: 57.9" "Not detected" "Not detected" "Region enhanced" "Detected in some" "basal ganglia: 9.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Region enriched" "Detected in some" 5 "basal ganglia: 7.4" "Region enriched" "Detected in all" 9 "basal ganglia: 26.2" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 35: Neurons - Synaptic function & neurogenesis" 5 DRD4 ENSG00000069696 "Dopamine receptor D4" P21917 11 637269-640706 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "Biological rhythms" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 9.8;Cone photoreceptor cells: 8.3;Ependymal cells: 15.1;pDCs: 16.9;Retinal bipolar cells: 12.1;Retinal pigment epithelial cells: 42.6;Rod photoreceptor cells: 49.7" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 14.4" "Cancer enhanced" "Detected in single" "Ovary Serous Cystadenocarcinoma (TCGA): 1.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Enteric glia cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA062682 Uncertain "Plasma membrane,Centrosome" NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 64: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 79: Photoreceptor cells - Phototransduction" 10 "Plasma membrane" Centrosome "HPA062682: " "unprognostic (1.24e-1)" "unprognostic (1.25e-1)" "unprognostic (3.92e-3)" "unprognostic (2.59e-2)" DRD5 "DRD1B, DRD1L2" ENSG00000169676 "Dopamine receptor D5" P21918 4 9781634-9784009 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Dystonia, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 2.6;lymphoid tissue: 1.3;stomach 1: 4.2" "Cell type enhanced" "Detected in some" "Adipocytes: 1.7;Brain excitatory neurons: 1.4;Brain inhibitory neurons: 1.2;Other brain neurons: 3.0;Parietal cells: 1.8;Retinal amacrine cells: 1.4" "Cell type enhanced" "Detected in some" "deep-layer intratelencephalic: 6.9;LAMP5-LHX6 and Chandelier: 8.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Skin - Inner root sheath cells" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "thalamus: 9.1" HPA048930 Supported NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 24: Neurons - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 109: Neurons - Neuronal signaling" 2 "HPA048930: " DRG1 NEDD3 ENSG00000185721 "Developmentally regulated GTP binding protein 1" Q9Y295 22 31399604-31530634 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" Hydrolase "Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 149.8" "Group enriched" "Detected in all" 4 "Early spermatids: 703.5;Late primary spermatocytes: 1074.6;Late spermatids: 871.0;Oocytes: 419.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001218 Enhanced Supported "Nucleoplasm,Nuclear bodies,Cytosol" No No 17000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 39: Testis - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 66: Non-specific - Mitochondria" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 241 "Nucleoplasm, Nuclear bodies" Cytosol "HPA001218: " "unprognostic (7.57e-3)" "unprognostic (1.86e-2)" "unprognostic (2.18e-1)" "unprognostic (2.08e-3)" "unprognostic (5.39e-3)" "unprognostic (1.37e-2)" "unprognostic (5.82e-2)" "unprognostic (1.99e-1)" "unprognostic (4.12e-3)" "unprognostic (8.19e-2)" "validated prognostic favorable (2.12e-8)" "validated prognostic favorable (7.38e-4)" "unprognostic (4.05e-1)" "validated prognostic unfavorable (3.41e-5)" "validated prognostic unfavorable (8.93e-7)" "unprognostic (5.21e-3)" "unprognostic (1.95e-2)" "unprognostic (4.57e-2)" "unprognostic (2.92e-3)" "unprognostic (5.66e-3)" "unprognostic (1.14e-1)" "potential prognostic unfavorable (3.68e-4)" "unprognostic (8.52e-2)" "unprognostic (1.31e-1)" "unprognostic (1.44e-2)" "unprognostic (6.86e-2)" "unprognostic (1.92e-1)" "unprognostic (2.59e-1)" "unprognostic (2.46e-1)" "unprognostic (1.26e-1)" "unprognostic (1.36e-1)" DRG2 ENSG00000108591 "Developmentally regulated GTP binding protein 2" P55039 17 18087892-18107970 "Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007716 Approved Supported Nucleoplasm,Vesicles,Cytosol No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 24: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 14 "Vesicles, Cytosol" Nucleoplasm "HPA007716: " "unprognostic (3.87e-2)" "unprognostic (6.55e-2)" "unprognostic (6.12e-2)" "unprognostic (1.31e-1)" "unprognostic (1.04e-1)" "unprognostic (2.75e-1)" "validated prognostic unfavorable (3.59e-4)" "validated prognostic unfavorable (1.14e-4)" "unprognostic (4.46e-3)" "unprognostic (1.07e-1)" "potential prognostic favorable (8.73e-4)" "unprognostic (1.34e-1)" "unprognostic (6.19e-2)" "unprognostic (2.73e-3)" "unprognostic (2.33e-1)" "unprognostic (2.81e-2)" "unprognostic (1.17e-1)" "unprognostic (3.14e-2)" "unprognostic (8.65e-3)" "unprognostic (2.43e-1)" "unprognostic (1.21e-1)" "unprognostic (2.18e-2)" "unprognostic (1.02e-2)" "unprognostic (4.17e-2)" "unprognostic (1.24e-1)" "unprognostic (8.53e-2)" "unprognostic (6.48e-2)" "unprognostic (1.01e-1)" "unprognostic (1.77e-1)" "unprognostic (1.37e-1)" "unprognostic (1.14e-1)" DRGX "DRG11, PRRXL1" ENSG00000165606 "Dorsal root ganglia homeobox" A6NNA5 10 49364066-49396089 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 9 "adrenal gland: 5.1;brain: 1.9" "Cell type enriched" "Detected in some" 18 "Adrenal medulla cells: 42.5" "Group enriched" "Detected in some" 5 "lower rhombic lip: 17.0;splatter: 9.2" "Cancer enhanced" "Detected in some" "Bladder Urothelial Carcinoma (TCGA): 1.2;Lung Adenocarcinoma (TCGA): 1.1" "Group enriched" "Detected in many" 9 "medulla oblongata: 9.3;pons: 22.2;spinal cord: 17.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Neuroblastoma: 5.3;Sarcoma: 2.7" "Adrenal gland - Adrenal medulla cells" "Region enriched" "Detected in single" 6 "pons and medulla: 3.9" "Group enriched" "Detected in some" 10 "cerebral cortex: 5.2;hippocampal formation: 2.1;medulla oblongata: 3.1;spinal cord: 4.9" HPA043978 Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 109: Neurons - Neuronal signaling" "Nucleoplasm, Nucleoli" Cytosol "HPA043978: " "unprognostic (3.29e-1)" "unprognostic (3.84e-2)" DRICH1 C22orf43 ENSG00000189269 "Aspartate rich 1" Q6PGQ1 22 23608452-23632321 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 16.0;testis: 44.0" "Group enriched" "Detected in many" 7 "Early spermatids: 762.0;Late spermatids: 1462.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Testis - Late spermatids" HPA020446 Approved Nucleoplasm,Nucleoli No No "Cluster 22: Epididymis - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 5 "Nucleoplasm, Nucleoli" "HPA020446: " "unprognostic (4.28e-2)" "unprognostic (4.68e-2)" "unprognostic (2.12e-1)" "unprognostic (1.62e-2)" "unprognostic (2.55e-2)" "unprognostic (4.36e-2)" "unprognostic (4.18e-1)" "unprognostic (1.39e-2)" "unprognostic (1.23e-1)" "unprognostic (1.13e-2)" DROSHA "Etohi2, HSA242976, RN3, RNASE3L, RNASEN" ENSG00000113360 "Drosha ribonuclease III" Q9NRR4 5 31400494-31532196 "Cancer-related genes, Enzymes, Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis, RNA-mediated gene silencing" "Endonuclease, Hydrolase, Nuclease, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031150 Supported Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 29: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 26 Nucleoplasm Cytosol "HPA031150: " "unprognostic (1.75e-1)" "unprognostic (2.49e-2)" "potential prognostic unfavorable (4.04e-4)" "unprognostic (2.23e-1)" "unprognostic (1.38e-1)" "unprognostic (1.93e-1)" "unprognostic (7.28e-3)" "unprognostic (1.31e-1)" "potential prognostic unfavorable (4.90e-4)" "potential prognostic favorable (2.28e-4)" "unprognostic (7.50e-2)" "unprognostic (1.01e-1)" "unprognostic (8.15e-3)" "unprognostic (1.32e-1)" "unprognostic (1.01e-1)" "unprognostic (3.65e-3)" "unprognostic (1.83e-1)" "unprognostic (6.01e-2)" "unprognostic (3.47e-2)" "unprognostic (1.62e-2)" "unprognostic (5.21e-2)" "unprognostic (1.49e-2)" "unprognostic (2.09e-1)" "unprognostic (3.85e-3)" "unprognostic (7.19e-2)" "unprognostic (2.73e-2)" "unprognostic (1.69e-1)" "unprognostic (2.38e-1)" "unprognostic (4.92e-3)" "unprognostic (3.01e-1)" DRP2 ENSG00000102385 "Dystrophin related protein 2" Q13474 X 101219769-101264502 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 12.4;lymphoid tissue: 4.4" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 26.9;Brain inhibitory neurons: 32.4;Gonadotrophs: 20.4;Lactotrophs: 10.1;Oligodendrocyte progenitor cells: 21.7;Other brain neurons: 15.7;Retinal amacrine cells: 23.9;Retinal bipolar cells: 6.2;Schwann cells: 20.5" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in single" "Glioblastoma Multiforme (TCGA): 2.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adrenal gland - Adrenal medulla cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 71.7" HPA002949 Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 35: Neurons - Synaptic function & neurogenesis" 2 "Nuclear speckles, Plasma membrane" "HPA002949: " "unprognostic (2.92e-1)" "unprognostic (3.51e-2)" "potential prognostic favorable (8.85e-5)" "unprognostic (3.25e-2)" "unprognostic (1.94e-1)" DSC1 CDHF1 ENSG00000134765 "Desmocollin 1" Q08554 18 31129236-31162856 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skin 1: 216.0" "Group enriched" "Detected in some" 8 "Cardiomyocytes: 44.7;Suprabasal keratinocytes: 145.3" "Cell type enhanced" "Detected in some" "astrocyte: 2.4" "Group enriched" "Detected in some" 7 "Head and Neck Squamous Cell Carcinoma (TCGA): 10.4;Skin Cutaneous Melanoma (TCGA): 6.2" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 8 "naive CD4 T-cell: 2.7;naive CD8 T-cell: 2.6" "Lineage enriched" "Detected in single" 8 "T-cells: 2.7" "Cancer enriched" "Detected in single" 7 "ovarian cancer: 6.4" "Heart muscle - Cardiomyocytes, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA075379 Enhanced NA NA 29000000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 37: Skin - Keratinization" "Cluster 53: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 26: Keratinocytes - Keratinization" 10 "HPA075379: " "potential prognostic unfavorable (3.72e-4)" "unprognostic (2.00e-2)" "unprognostic (9.69e-2)" "unprognostic (4.38e-2)" DSC2 "CDHF2, DSC3" ENSG00000134755 "Desmocollin 2" Q02487 18 31058840-31102522 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 160.9;lymphoid tissue: 60.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 339.0;Colonocytes: 404.7;Esophageal apical cells: 2014.7;Esophageal basal cells: 337.3;Esophageal suprabasal cells: 1659.0;Neutrophils: 437.8;Ocular epithelial cells: 1279.1;Suprabasal keratinocytes: 1490.2" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 26.9" "Cancer enhanced" "Detected in all" "Head and Neck Squamous Cell Carcinoma (TCGA): 142.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "eosinophil: 29.9;neutrophil: 8.4" "Lineage enriched" "Detected in many" 14 "granulocytes: 29.9" "Low cancer specificity" "Detected in many" "Prostate - Prostate glandular cells, Skin - Outer root sheath cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA011911, HPA012615" Enhanced Supported "Endoplasmic reticulum,Plasma membrane" NA NA 18000000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 9 "Plasma membrane" "Endoplasmic reticulum" "HPA011911: , HPA012615: " "unprognostic (1.77e-2)" "unprognostic (1.48e-2)" "unprognostic (3.79e-1)" "unprognostic (1.95e-1)" "validated prognostic favorable (6.39e-4)" "validated prognostic favorable (6.93e-4)" "unprognostic (5.42e-2)" "unprognostic (2.80e-1)" "unprognostic (5.56e-2)" "unprognostic (1.23e-2)" "potential prognostic favorable (3.24e-4)" "unprognostic (1.17e-2)" "unprognostic (1.02e-2)" "unprognostic (6.58e-3)" "potential prognostic unfavorable (3.82e-4)" "potential prognostic unfavorable (1.05e-4)" "unprognostic (1.28e-2)" "unprognostic (8.34e-2)" "unprognostic (1.85e-1)" "unprognostic (1.59e-1)" "unprognostic (1.12e-1)" "unprognostic (2.92e-3)" "unprognostic (5.03e-3)" "unprognostic (2.26e-1)" "unprognostic (1.21e-1)" "unprognostic (5.45e-2)" "unprognostic (5.65e-2)" "unprognostic (3.54e-1)" "unprognostic (1.46e-1)" "unprognostic (1.44e-1)" "unprognostic (7.58e-2)" DSC3 "CDHF3, DSC, DSC1, DSC2, DSC4" ENSG00000134762 "Desmocollin 3" Q14574 18 30989365-31042815 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" Hypotrichosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 93.2;skin 1: 351.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 836.6;Esophageal apical cells: 241.7;Esophageal basal cells: 506.0;Esophageal suprabasal cells: 534.3;Ocular epithelial cells: 841.5;Prostatic hillock cells: 147.8;Suprabasal keratinocytes: 1019.9" "Cell type enhanced" "Detected in some" "amygdala excitatory: 1.9;fibroblast: 2.7;miscellaneous: 3.9" "Group enriched" "Detected in many" 6 "Bladder Urothelial Carcinoma (TCGA): 44.6;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 130.8;Head and Neck Squamous Cell Carcinoma (TCGA): 161.2;Lung Squamous Cell Carcinoma (TCGA): 69.0" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Bladder cancer: 21.2;cervical cancer: 33.3;Esophageal cancer: 44.7;Gallbladder cancer: 15.6;head and neck cancer: 54.7" "Adipose visceral - Mesothelial cells, Breast - Breast myoepithelial cells, Skin - Keratinocyte (other)" "Region enhanced" "Detected in some" "hippocampal formation: 3.3" "Low region specificity" "Detected in many" "CAB037328, HPA049265, HPA073937" Enhanced Enhanced "Plasma membrane,Cell Junctions" NA NA 8900000 "Cluster 58: Skin - Keratinization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 10 "Plasma membrane, Cell Junctions" "CAB037328: , HPA049265: , HPA073937: " "unprognostic (2.85e-2)" "unprognostic (1.09e-2)" "unprognostic (1.76e-1)" "unprognostic (1.41e-1)" "unprognostic (8.41e-3)" "unprognostic (1.43e-2)" "unprognostic (3.71e-3)" "unprognostic (1.35e-1)" "unprognostic (2.73e-3)" "unprognostic (2.26e-1)" "unprognostic (3.02e-2)" "unprognostic (2.63e-1)" "unprognostic (3.82e-3)" "potential prognostic unfavorable (1.10e-4)" "unprognostic (2.03e-1)" "unprognostic (2.38e-2)" "unprognostic (3.33e-1)" "unprognostic (1.78e-1)" "unprognostic (2.29e-2)" "unprognostic (1.69e-1)" "unprognostic (3.87e-1)" DSCAM "CHD2-42, CHD2-52" ENSG00000171587 "DS cell adhesion molecule" O60469 21 40010999-40847158 "Plasma proteins, Predicted membrane proteins" "Cell adhesion, Neurogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 6.8;pituitary gland: 3.9;retina: 1.7" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 941.8;Brain inhibitory neurons: 1013.5;Lactotrophs: 2491.5;Microglia: 1230.2;Oligodendrocyte progenitor cells: 7951.4;Oligodendrocytes: 1297.6;Other brain neurons: 1355.6;Pituitary stem cells: 5253.1;Retinal amacrine cells: 1189.7;Retinal bipolar cells: 884.1;Retinal ganglion cells: 3109.5;Somatotrophs: 1575.4;Thyrotrophs: 2228.7" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 6349.4;oligodendrocyte precursor cell: 9545.4" "Cancer enriched" "Detected in single" 15 "Glioblastoma Multiforme (TCGA): 6.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019324, HPA057493" Enhanced Approved "Golgi apparatus,Cytosol" "Intracellular and membrane" "Cell adhesion" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 3 "Golgi apparatus" Cytosol "HPA019324: , HPA057493: " "unprognostic (1.04e-1)" "unprognostic (2.05e-3)" DSCAML1 KIAA1132 ENSG00000177103 "DS cell adhesion molecule like 1" Q8TD84 11 117427772-117817525 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Neurogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 9.9;retina: 18.7" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 378.8;Loop of henle epithelial cells: 399.1;Oligodendrocyte progenitor cells: 651.3;Oligodendrocytes: 884.9;Proximal tubule cells: 340.7;Renal collecting duct intercalated cells: 536.1;Retinal bipolar cells: 1266.5;Rod photoreceptor cells: 2159.5" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 5.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney cancer: 4.2;Uterine cancer: 5.2" "Adipose visceral - Mesothelial cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035230 Uncertain NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 11: White matter - Signal transduction" "Cluster 1: Neuronal - Visual perception" "Cluster 79: Photoreceptor cells - Phototransduction" "HPA035230: " "unprognostic (1.70e-1)" "unprognostic (4.13e-2)" "unprognostic (4.86e-2)" "potential prognostic favorable (3.23e-5)" "unprognostic (2.65e-2)" "potential prognostic favorable (8.46e-6)" "unprognostic (5.32e-2)" "unprognostic (2.17e-2)" "unprognostic (8.15e-2)" "unprognostic (2.54e-3)" "unprognostic (2.60e-2)" "unprognostic (2.32e-1)" "unprognostic (1.10e-1)" DSCC1 "DCC1, hDCC1, MGC5528" ENSG00000136982 "DNA replication and sister chromatid cohesion 1" Q9BVC3 8 119833976-119855894 "Predicted intracellular proteins" "Cell cycle, DNA replication" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 9.2" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 33.5;Erythrocyte progenitors: 43.9;Extravillous trophoblasts: 21.7;Gastric progenitor cells: 23.1;Megakaryocyte progenitors: 48.0;Monocyte progenitors: 21.7;Oocytes: 78.3;Undifferentiated spermatogonia: 22.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Spleen - Mitotic cells (Spleen), Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA023780, HPA024401" Uncertain Approved Nucleoplasm NA Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 22 Nucleoplasm "HPA023780: , HPA024401: " "unprognostic (8.29e-3)" "unprognostic (6.00e-3)" "unprognostic (1.97e-1)" "unprognostic (1.44e-1)" "unprognostic (1.30e-1)" "unprognostic (1.19e-2)" "unprognostic (4.27e-1)" "unprognostic (1.65e-1)" "unprognostic (1.22e-1)" "unprognostic (8.51e-2)" "unprognostic (4.95e-2)" "potential prognostic unfavorable (6.86e-4)" "validated prognostic unfavorable (4.63e-6)" "validated prognostic unfavorable (3.97e-6)" "potential prognostic unfavorable (7.53e-5)" "unprognostic (1.80e-2)" "unprognostic (1.20e-1)" "unprognostic (1.98e-2)" "unprognostic (1.57e-3)" "unprognostic (7.91e-2)" "unprognostic (5.03e-3)" "unprognostic (2.16e-3)" "unprognostic (3.19e-2)" "unprognostic (7.43e-2)" "unprognostic (1.16e-1)" "unprognostic (9.06e-3)" "unprognostic (3.54e-2)" "unprognostic (1.53e-1)" "unprognostic (7.29e-2)" "unprognostic (1.84e-2)" DSE "DS-Epi1, DSEPI, SART2" ENSG00000111817 "Dermatan sulfate epimerase" Q9UL01 6 116254173-116444861 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Isomerase "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ependymal cells: 395.2;Late spermatids: 523.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 5.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Adrenal gland - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014764 Uncertain "Intracellular and membrane" Enzyme NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 1 "HPA014764: " "unprognostic (4.56e-1)" "unprognostic (5.24e-2)" "unprognostic (1.94e-1)" "unprognostic (1.04e-3)" "unprognostic (3.99e-2)" "unprognostic (1.67e-1)" "unprognostic (2.81e-3)" "unprognostic (3.04e-1)" "unprognostic (6.80e-2)" "unprognostic (3.50e-1)" "unprognostic (2.70e-2)" "unprognostic (8.34e-2)" "unprognostic (2.82e-1)" "unprognostic (1.24e-1)" "unprognostic (1.54e-2)" "unprognostic (8.57e-2)" "potential prognostic unfavorable (2.07e-4)" "unprognostic (1.80e-2)" "potential prognostic unfavorable (3.94e-4)" "unprognostic (1.23e-3)" "unprognostic (5.39e-2)" "unprognostic (6.00e-2)" "unprognostic (1.75e-2)" "unprognostic (3.46e-1)" "unprognostic (5.97e-2)" "unprognostic (3.68e-3)" "unprognostic (8.73e-2)" "unprognostic (1.08e-3)" "unprognostic (1.23e-1)" "unprognostic (1.61e-2)" "unprognostic (1.12e-1)" DSEL "C18orf4, DE-epi2, FLJ11477, NCAG1" ENSG00000171451 "Dermatan sulfate epimerase like" Q8IZU8 18 67506587-67516720 "Predicted membrane proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 27.2;Brain inhibitory neurons: 55.1;Oligodendrocyte progenitor cells: 155.5;Oligodendrocytes: 106.9;Other brain neurons: 37.9;Proximal tubule cells: 15.4" "Cell type enhanced" "Detected in all" "midbrain-derived inhibitory: 222.6;oligodendrocyte precursor cell: 195.6" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 13.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Heart muscle - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060942 Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" "Plasma membrane" Nucleoplasm "HPA060942: " "unprognostic (1.42e-1)" "unprognostic (2.53e-1)" "unprognostic (1.07e-1)" "unprognostic (4.23e-2)" "unprognostic (3.91e-1)" "unprognostic (2.15e-1)" "unprognostic (2.32e-2)" "unprognostic (1.86e-2)" "potential prognostic favorable (1.28e-6)" "unprognostic (4.54e-3)" "unprognostic (5.61e-2)" "potential prognostic unfavorable (6.21e-4)" "unprognostic (2.58e-2)" "unprognostic (1.05e-2)" "unprognostic (1.66e-1)" "unprognostic (4.28e-2)" "unprognostic (1.82e-1)" "unprognostic (8.90e-2)" "unprognostic (6.48e-2)" "unprognostic (5.94e-2)" "unprognostic (3.22e-2)" "unprognostic (1.64e-1)" "unprognostic (4.55e-2)" "unprognostic (4.66e-2)" "unprognostic (6.82e-2)" "unprognostic (9.65e-2)" DSG1 "CDHF4, DSG" ENSG00000134760 "Desmoglein 1" Q02413 18 31318160-31359246 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Hypotrichosis, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "skin 1: 533.0" "Group enriched" "Detected in some" 4 "Basal keratinocytes: 335.3;Ocular epithelial cells: 912.7;Suprabasal keratinocytes: 1054.4" "Not detected" "Not detected" "Group enriched" "Detected in many" 8 "Head and Neck Squamous Cell Carcinoma (TCGA): 60.7;Skin Cutaneous Melanoma (TCGA): 20.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 1.4;Esophageal cancer: 1.7;ovarian cancer: 3.3" "Liver - Hepatocytes, Minor Salivary Gland - Minor salivary gland basal cells, Skin - Keratinocyte (other), Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA022128, HPA074188" Enhanced NA NA 86000000 "Cluster 37: Skin - Keratinization" "Cluster 5: Rhabdoid - Unknown function" "Cluster 100: Stratified epithelial cells - Barrier functions" 18 "HPA022128: , HPA074188: " "unprognostic (1.55e-2)" "unprognostic (7.21e-3)" "unprognostic (4.18e-2)" "unprognostic (2.54e-2)" "unprognostic (2.31e-2)" "unprognostic (9.11e-3)" "unprognostic (1.04e-3)" "unprognostic (1.43e-2)" "unprognostic (4.96e-1)" "unprognostic (8.85e-2)" DSG2 CDHF5 ENSG00000046604 "Desmoglein 2" Q14126 18 31498177-31549008 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 99.0;parathyroid gland: 148.5" "Cell type enhanced" "Detected in many" "Colonocytes: 380.6;Foveolar cells: 389.2;Gastric progenitor cells: 241.0;Parietal cells: 235.1;Urothelial cells: 345.5" "Cell type enriched" "Detected in many" 5 "choroid plexus epithelial cell: 54.3" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 10 "choroid plexus: 63.2" "Immune cell enriched" "Detected in single" 12 "basophil: 8.7" "Lineage enriched" "Detected in single" 12 "granulocytes: 8.7" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Skeletal muscle - Endothelial cells, Stomach - Gastric mucous cells, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA004896, CAB025122" Enhanced Supported "Vesicles,Plasma membrane,Cell Junctions" NA NA 94000000 "Cluster 41: Basophils - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 36: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 69: Urothelial cells - Basic cellular functions" 29 "Cell Junctions" "Vesicles, Plasma membrane" "CAB025122: , HPA004896: " "unprognostic (7.88e-2)" "unprognostic (2.01e-2)" "unprognostic (4.97e-1)" "potential prognostic unfavorable (1.72e-4)" "unprognostic (7.61e-3)" "unprognostic (9.20e-2)" "potential prognostic unfavorable (8.44e-5)" "unprognostic (2.32e-3)" "unprognostic (4.89e-3)" "unprognostic (6.83e-3)" "potential prognostic favorable (2.68e-7)" "unprognostic (1.77e-2)" "unprognostic (2.05e-2)" "unprognostic (1.57e-3)" "unprognostic (1.06e-3)" "potential prognostic unfavorable (4.07e-6)" "unprognostic (1.43e-1)" "unprognostic (2.47e-1)" "unprognostic (2.74e-2)" "unprognostic (9.21e-2)" "unprognostic (4.76e-1)" "potential prognostic unfavorable (4.26e-4)" "unprognostic (9.83e-3)" "unprognostic (1.47e-1)" "unprognostic (3.84e-2)" "unprognostic (5.30e-2)" "unprognostic (8.51e-2)" "unprognostic (1.70e-1)" "unprognostic (1.93e-1)" "unprognostic (1.26e-1)" "unprognostic (1.66e-1)" DSG3 CDHF6 ENSG00000134757 "Desmoglein 3" P32926 18 31447741-31478702 "Disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 93.0;esophagus: 296.1;vagina: 115.5" "Group enriched" "Detected in many" 11 "Basal keratinocytes: 1104.5;Esophageal apical cells: 4223.7;Esophageal basal cells: 1625.9;Esophageal suprabasal cells: 3206.1;Ocular epithelial cells: 2845.1;Suprabasal keratinocytes: 2019.9" "Group enriched" "Detected in some" 5 "hippocampal CA1-3: 1.1;upper-layer intratelencephalic: 1.7" "Group enriched" "Detected in many" 4 "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 160.8;Head and Neck Squamous Cell Carcinoma (TCGA): 251.6;Lung Squamous Cell Carcinoma (TCGA): 98.4" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 53 "basophil: 8.1" "Lineage enriched" "Detected in single" 82 "granulocytes: 8.1" "Cancer enhanced" "Detected in many" "Esophageal cancer: 39.7;Gallbladder cancer: 47.1;head and neck cancer: 72.0" "Prostate - Urothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA046864, HPA056863, CAB069880" Enhanced NA NA 160000 "Cluster 46: Basophils - Proteolysis" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 13 "CAB069880: , HPA046864: , HPA056863: " "unprognostic (1.05e-1)" "unprognostic (9.29e-3)" "unprognostic (2.41e-1)" "unprognostic (2.90e-1)" "unprognostic (4.18e-2)" "unprognostic (8.21e-2)" "unprognostic (2.07e-2)" "unprognostic (3.00e-1)" "unprognostic (1.69e-3)" "unprognostic (1.35e-2)" "unprognostic (3.19e-1)" "potential prognostic unfavorable (1.03e-5)" "unprognostic (2.39e-3)" "unprognostic (2.99e-1)" "unprognostic (1.36e-1)" "unprognostic (1.20e-1)" "unprognostic (8.83e-2)" "unprognostic (1.32e-1)" "unprognostic (1.98e-1)" DSG4 "CDHF13, LAH" ENSG00000175065 "Desmoglein 4" Q86SJ6 18 31376777-31414912 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "skin 1: 2.4" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 3.6;Colonocytes: 2.4;Early spermatids: 1.8;Epicardial cells: 2.3;Esophageal apical cells: 2.3;Esophageal suprabasal cells: 1.6;Late primary spermatocytes: 3.2;Late spermatids: 2.1;Medullary thymic epithelial cells: 7.2;Neuroendocrine cells: 2.2;Ocular epithelial cells: 1.9;Paneth cells: 7.7;Prostatic hillock cells: 2.9;Suprabasal keratinocytes: 5.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "colorectal cancer: 1.8" "Skin - Hair cortex cells, Skin - Inner root sheath cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA059456, HPA079244" Enhanced NA NA 73000 "Cluster 37: Skin - Keratinization" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 85: Squamous epithelial cells - Keratinization" 1 "HPA059456: , HPA079244: " DSN1 "C20orf172, dJ469A13.2, hKNL-3, KNL3, MIS13" ENSG00000149636 "DSN1 component of MIS12 kinetochore complex" Q9H410 20 36751791-36773818 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 87.2;Differentiating spermatogonia: 81.1;Early primary spermatocytes: 147.5;Migrating cytotrophoblasts: 72.6;Oocytes: 101.3;Syncytiotrophoblasts: 90.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002813, HPA030627" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Nuclear bodies,Kinetochore,Cytosol" Yes Yes "Cluster 41: Basophils - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 27: Non-specific - Cell proliferation" 51 Nucleoplasm "Nucleoli fibrillar center, Nuclear bodies, Kinetochore, Cytosol" "HPA002813: , HPA030627: " "unprognostic (1.07e-1)" "unprognostic (2.61e-2)" "unprognostic (4.09e-2)" "unprognostic (2.95e-2)" "unprognostic (3.98e-1)" "unprognostic (3.23e-2)" "unprognostic (2.26e-2)" "unprognostic (2.30e-1)" "unprognostic (2.90e-2)" "unprognostic (1.28e-2)" "unprognostic (3.39e-3)" "unprognostic (3.53e-2)" "unprognostic (2.14e-1)" "validated prognostic unfavorable (2.95e-4)" "validated prognostic unfavorable (1.77e-5)" "unprognostic (8.51e-2)" "unprognostic (1.29e-2)" "unprognostic (9.56e-2)" "unprognostic (1.73e-1)" "unprognostic (1.18e-1)" "unprognostic (4.48e-1)" "unprognostic (1.56e-2)" "unprognostic (1.94e-3)" "unprognostic (6.13e-2)" "unprognostic (1.18e-2)" "unprognostic (1.06e-2)" "unprognostic (1.73e-1)" "unprognostic (1.60e-2)" "unprognostic (2.08e-1)" "unprognostic (6.78e-2)" "unprognostic (3.25e-2)" DSP "DPI, DPII, KPPS2, PPKS2" ENSG00000096696 Desmoplakin P15924 6 7541617-7586714 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Cardiomyopathy, Disease variant, Epidermolysis bullosa, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 437.5;skin 1: 807.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 1933.0;Esophageal apical cells: 3342.1;Esophageal basal cells: 1428.6;Esophageal suprabasal cells: 3402.7;Ocular epithelial cells: 2856.0;Suprabasal keratinocytes: 4671.6" "Group enriched" "Detected in many" 5 "choroid plexus epithelial cell: 20.6;endothelial cell: 40.8;fibroblast: 58.6;hippocampal dentate gyrus: 23.6" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 478.3" "Region enriched" "Detected in all" 4 "choroid plexus: 42.3" "Immune cell enriched" "Detected in single" 16 "naive B-cell: 2.3" "Lineage enriched" "Detected in single" 24 "B-cells: 2.3" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Pituitary gland - Thyrotropes, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Region enriched" "Detected in single" 23 "hippocampal formation: 11.6" "Region enhanced" "Detected in many" "spinal cord: 12.7" "CAB037324, HPA045840, HPA054950" Enhanced Supported "Cell Junctions" NA NA 130000000 "Cluster 34: B-cells - Unknown function" "Cluster 58: Skin - Keratinization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 45 "Cell Junctions" "CAB037324: , HPA045840: , HPA054950: " "unprognostic (5.26e-2)" "unprognostic (8.88e-2)" "unprognostic (2.63e-1)" "unprognostic (9.03e-2)" "unprognostic (2.22e-2)" "unprognostic (5.96e-2)" "unprognostic (1.08e-2)" "unprognostic (2.24e-2)" "unprognostic (3.10e-2)" "validated prognostic favorable (3.33e-5)" "validated prognostic favorable (9.83e-4)" "unprognostic (1.29e-1)" "unprognostic (1.11e-1)" "unprognostic (7.94e-2)" "unprognostic (2.91e-3)" "unprognostic (1.64e-2)" "unprognostic (3.23e-2)" "unprognostic (2.13e-1)" "unprognostic (9.11e-2)" "unprognostic (3.22e-3)" "unprognostic (1.19e-1)" "unprognostic (3.51e-2)" "unprognostic (2.22e-2)" "unprognostic (2.86e-2)" "unprognostic (4.10e-1)" "unprognostic (5.16e-2)" "unprognostic (2.81e-1)" "unprognostic (2.10e-1)" "unprognostic (4.20e-2)" "unprognostic (2.69e-1)" DSPP "DFNA39, DGI1, DMP3" ENSG00000152591 "Dentin sialophosphoprotein" Q9NZW4 4 87608529-87616873 "Disease related genes, Human disease related genes, Predicted secreted proteins" Biomineralization "Deafness, Disease variant" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 115 "Rhabdoid: 11.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA036230 Uncertain "Secreted in other tissues" Other NA NA 34000 "Cluster 5: Rhabdoid - Unknown function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "HPA036230: " DST "BP240, BPA, BPAG1, CATX-15, FLJ13425, FLJ21489, FLJ30627, FLJ32235, KIAA0728, MACF2" ENSG00000151914 Dystonin Q03001 6 56457987-56954830 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Actin-binding, Muscle protein" "Cancer-related genes, Epidermolysis bullosa, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 4071.0;Oligodendrocytes: 1791.2;Podocytes: 1829.7;Salivary myoepithelial cells: 2557.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.2" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Breast - Breast myoepithelial cells, Lung - Fibroblasts_1, Minor Salivary Gland - Minor salivary glandular cells, Spleen - Endothelial cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030200 Uncertain Approved Nucleoplasm,Microtubules,Cytosol NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 26: Keratinocytes - Keratinization" 32 "Nucleoplasm, Microtubules" Cytosol "HPA030200: " "unprognostic (4.29e-1)" "unprognostic (1.09e-3)" "unprognostic (1.95e-2)" "unprognostic (1.71e-1)" "unprognostic (4.31e-2)" "unprognostic (3.12e-3)" "unprognostic (1.29e-2)" "unprognostic (1.06e-1)" "unprognostic (1.27e-1)" "unprognostic (9.80e-2)" "unprognostic (3.18e-1)" "unprognostic (9.28e-2)" "unprognostic (3.92e-2)" "unprognostic (1.88e-1)" "unprognostic (1.57e-1)" "unprognostic (4.33e-2)" "unprognostic (6.14e-3)" "unprognostic (1.84e-1)" "unprognostic (5.68e-2)" "unprognostic (2.19e-2)" "unprognostic (1.97e-1)" "unprognostic (9.13e-2)" "unprognostic (1.48e-2)" "unprognostic (1.41e-1)" "unprognostic (2.08e-1)" "unprognostic (9.55e-3)" "unprognostic (9.81e-2)" "unprognostic (9.79e-3)" "unprognostic (4.88e-2)" "unprognostic (1.99e-1)" "unprognostic (6.56e-2)" DSTN "ACTDP, ADF" ENSG00000125868 "Destrin, actin depolymerizing factor" P60981 20 17570075-17609919 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 2615.7" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 3626.8;Esophageal apical cells: 3180.9;Smooth muscle cells: 3354.9;Vascular smooth muscle cells: 4533.4" "Cell type enriched" "Detected in all" 4 "vascular associated smooth muscle cell: 1186.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Colon - Smooth muscle cells, Prostate - Smooth muscle cells, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037094, HPA077782" Approved Approved "Plasma membrane" NA NA 5800000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 27: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 62: Smooth muscle cells - Muscle contraction" 22 "Plasma membrane" "CAB037094: , HPA077782: " "unprognostic (4.71e-2)" "potential prognostic unfavorable (2.63e-4)" "unprognostic (7.58e-3)" "unprognostic (4.13e-3)" "unprognostic (5.09e-2)" "unprognostic (1.01e-1)" "unprognostic (2.65e-2)" "potential prognostic unfavorable (4.78e-4)" "unprognostic (9.94e-3)" "unprognostic (2.92e-1)" "potential prognostic favorable (1.22e-7)" "unprognostic (1.37e-2)" "unprognostic (2.60e-2)" "unprognostic (1.66e-3)" "unprognostic (9.24e-2)" "unprognostic (4.33e-1)" "unprognostic (1.88e-1)" "unprognostic (7.15e-3)" "potential prognostic unfavorable (9.17e-4)" "unprognostic (2.98e-1)" "unprognostic (2.09e-1)" "unprognostic (4.13e-2)" "unprognostic (1.35e-2)" "unprognostic (1.19e-1)" "unprognostic (1.34e-1)" "unprognostic (1.69e-2)" "unprognostic (8.74e-2)" "unprognostic (8.08e-2)" "unprognostic (2.32e-1)" "unprognostic (1.33e-1)" "unprognostic (2.91e-1)" DSTYK "DustyPK, KIAA0472, RIP5, RIPK5, SPG23" ENSG00000133059 "Dual serine/threonine and tyrosine protein kinase" Q6XUX3 1 205142505-205211702 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Melanocytes: 288.6;Neutrophil progenitors: 180.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Endothelial cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044140 Approved NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 65: Brain - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 61: Schwann cells & Melanocytes - Mixed function" "HPA044140: " "unprognostic (1.52e-1)" "potential prognostic unfavorable (2.85e-4)" "unprognostic (3.60e-1)" "unprognostic (4.09e-2)" "unprognostic (9.31e-2)" "unprognostic (2.06e-1)" "unprognostic (1.67e-1)" "unprognostic (5.70e-2)" "unprognostic (2.60e-1)" "unprognostic (2.55e-3)" "potential prognostic favorable (4.56e-5)" "unprognostic (4.75e-3)" "unprognostic (6.85e-3)" "unprognostic (8.43e-2)" "unprognostic (1.79e-1)" "unprognostic (1.07e-2)" "unprognostic (2.31e-2)" "unprognostic (5.97e-2)" "unprognostic (1.02e-1)" "unprognostic (1.16e-1)" "unprognostic (1.57e-3)" "unprognostic (5.28e-3)" "unprognostic (9.51e-2)" "unprognostic (8.99e-2)" "unprognostic (6.84e-3)" "unprognostic (1.05e-2)" "unprognostic (8.90e-2)" "unprognostic (2.97e-2)" "unprognostic (1.75e-1)" "unprognostic (2.92e-1)" "unprognostic (3.35e-1)" DTD1 "bA379J5.3, bA555E18.1, C20orf88, DUEB, HARS2, MGC119131, MGC41905, pqn-68" ENSG00000125821 "D-aminoacyl-tRNA deacylase 1" Q8TEA8 20 18587942-18766644 "Enzymes, Predicted intracellular proteins" "DNA replication" "DNA-binding, Hydrolase, RNA-binding, tRNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 138.8;Early primary spermatocytes: 128.2;Megakaryocytes: 272.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040981 Uncertain Uncertain Nucleoli,Cytosol NA NA 310000 "Cluster 15: NK-cells - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 9: Non-specific - Receptor signaling" "Cluster 62: Non-specific - Plasma proteins" "Cluster 47: Platelets - Hemostasis" 1 "Nucleoli, Cytosol" "HPA040981: " "unprognostic (1.92e-1)" "unprognostic (2.54e-1)" "unprognostic (2.38e-1)" "unprognostic (1.45e-1)" "unprognostic (5.95e-2)" "unprognostic (2.49e-1)" "unprognostic (1.22e-1)" "unprognostic (7.71e-2)" "unprognostic (1.83e-1)" "unprognostic (5.19e-2)" "unprognostic (6.29e-3)" "unprognostic (7.63e-2)" "unprognostic (6.86e-2)" "unprognostic (1.44e-3)" "potential prognostic unfavorable (3.69e-4)" "unprognostic (7.49e-2)" "unprognostic (2.90e-2)" "unprognostic (1.29e-1)" "unprognostic (1.18e-1)" "unprognostic (2.50e-1)" "unprognostic (3.72e-1)" "unprognostic (3.62e-1)" "unprognostic (1.37e-1)" "unprognostic (1.65e-1)" "unprognostic (8.03e-2)" "unprognostic (7.00e-2)" "unprognostic (4.39e-1)" "unprognostic (1.97e-1)" "unprognostic (2.75e-1)" "unprognostic (1.24e-1)" "unprognostic (2.58e-1)" DTD2 "C14orf126, MGC9912" ENSG00000129480 "D-aminoacyl-tRNA deacylase 2" Q96FN9 14 31446036-31457506 "Enzymes, Predicted intracellular proteins" "Hydrolase, RNA-binding, tRNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Early spermatids: 3.9;Fallopian tube ciliated cells: 3.0;Late primary spermatocytes: 7.4;Late spermatids: 7.7;Megakaryocyte progenitors: 3.0" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001117 Approved Approved Vesicles NA NA "Cluster 24: Non-specific - Transcription" "Cluster 36: Brain & Liver - Signaling" "Cluster 11: White matter - Signal transduction" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" Vesicles "HPA001117: " "unprognostic (1.14e-1)" "unprognostic (6.50e-2)" "unprognostic (2.42e-3)" "unprognostic (2.52e-3)" "unprognostic (1.18e-1)" "unprognostic (1.97e-1)" "unprognostic (2.33e-1)" "unprognostic (8.89e-3)" "unprognostic (5.02e-3)" "unprognostic (4.78e-3)" "unprognostic (3.77e-2)" "unprognostic (2.35e-1)" "unprognostic (6.15e-3)" "unprognostic (4.37e-2)" "unprognostic (1.06e-2)" "unprognostic (1.39e-2)" "unprognostic (2.23e-2)" "unprognostic (1.62e-1)" "unprognostic (8.67e-2)" "unprognostic (3.94e-1)" "unprognostic (9.18e-2)" "unprognostic (3.77e-1)" "unprognostic (5.19e-2)" "unprognostic (1.14e-1)" "unprognostic (4.19e-2)" "unprognostic (3.29e-1)" "unprognostic (2.62e-2)" "potential prognostic unfavorable (7.34e-4)" "unprognostic (3.65e-3)" DTHD1 FLJ16686 ENSG00000197057 "Death domain containing 1" Q6ZMT9 4 36281616-36347511 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 12.9;lymphoid tissue: 3.7" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 560.8;Ependymal cells: 1132.4;Epididymal efferent duct ciliated cells: 279.5;Fallopian tube ciliated cells: 464.3;NK-cells: 206.0;Respiratory ciliated cells: 978.6;T-cells: 128.2" "Cell type enriched" "Detected in some" 7 "ependymal cell: 1239.2" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "gdT-cell: 3.4" "Lineage enriched" "Detected in single" 5 "T-cells: 3.4" "Not detected" "Not detected" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - T-cells, Prostate - T-cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in single" "Region enhanced" "Detected in many" "midbrain: 46.9" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" "unprognostic (2.11e-2)" "unprognostic (2.12e-2)" "unprognostic (1.99e-1)" "unprognostic (2.58e-1)" "unprognostic (2.63e-1)" "unprognostic (2.11e-2)" "unprognostic (2.01e-2)" DTL "CDT2, DCAF2, L2DTL, RAMP" ENSG00000143476 "Denticleless E3 ubiquitin protein ligase homolog" Q9NZJ0 1 212035553-212107400 "Essential proteins, Predicted intracellular proteins" "Biological rhythms, DNA damage, DNA replication, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 13.8;intestine: 4.5;lymphoid tissue: 13.2;placenta: 3.7;testis: 12.8" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 54.5;Early primary spermatocytes: 78.0;Erythrocyte progenitors: 141.9;Extravillous trophoblasts: 38.6;Late primary spermatocytes: 59.5;Megakaryocyte progenitors: 117.8;Megakaryocyte-Erythroid progenitors: 49.9;Migrating cytotrophoblasts: 42.6;Monocyte progenitors: 102.1;Neutrophil progenitors: 77.7" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 2.0" "Lineage enriched" "Detected in single" 8 "T-cells: 2.0" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA028016, HPA032023, HPA032031" Supported Supported Nucleoplasm,Nucleoli,Cytosol Yes Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 45: Non-specific - Nuclear processes" "Cluster 27: Non-specific - Cell proliferation" 36 Nucleoplasm "Nucleoli, Cytosol" "HPA028016: , HPA032023: , HPA032031: " "unprognostic (1.23e-1)" "unprognostic (1.40e-1)" "unprognostic (7.00e-2)" "unprognostic (1.90e-2)" "unprognostic (3.71e-2)" "unprognostic (4.49e-2)" "unprognostic (3.38e-1)" "unprognostic (1.40e-3)" "unprognostic (6.77e-2)" "unprognostic (3.35e-2)" "potential prognostic unfavorable (1.50e-4)" "potential prognostic unfavorable (1.68e-7)" "validated prognostic unfavorable (1.88e-4)" "validated prognostic unfavorable (3.93e-5)" "validated prognostic unfavorable (8.52e-7)" "validated prognostic unfavorable (2.51e-4)" "unprognostic (3.71e-2)" "unprognostic (6.00e-2)" "unprognostic (3.42e-1)" "unprognostic (1.50e-1)" "potential prognostic unfavorable (3.66e-4)" "unprognostic (2.53e-2)" "unprognostic (4.27e-2)" "unprognostic (3.50e-1)" "unprognostic (4.25e-3)" "unprognostic (7.39e-2)" "unprognostic (3.63e-1)" "unprognostic (1.42e-2)" "unprognostic (1.51e-1)" DTNA "D18S892E, DRP3, DTN, DTN-1, DTN-2, DTN-3" ENSG00000134769 "Dystrobrevin alpha" Q9Y4J8 18 34493291-34891844 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Cardiomyopathy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 204.2;choroid plexus: 72.0;heart muscle: 140.1;skeletal muscle: 152.8;tongue: 197.5" "Cell type enhanced" "Detected in many" "Astrocytes: 3051.9;Bergmann glia: 5155.1;Cardiomyocytes: 993.4;Ependymal cells: 1605.0;Myonuclei: 1700.4;Pancreatic acinar cells: 1233.1;Pituicytes/FSCs: 963.4" "Cell type enhanced" "Detected in all" "astrocyte: 3777.2;Bergmann glia: 5440.0" "Cancer enriched" "Detected in all" 15 "Glioblastoma Multiforme (TCGA): 197.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "dendritic cells: 3.4;T-cells: 4.4" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015196, HPA071177" Enhanced Approved "Nucleoplasm,Cell Junctions,Intermediate filaments" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 28: Astrocytes - Homeostasis & neuron support" 21 "Cell Junctions, Intermediate filaments" Nucleoplasm "CAB015196: , HPA071177: " "unprognostic (1.75e-1)" "unprognostic (6.17e-2)" "unprognostic (1.32e-1)" "unprognostic (6.70e-2)" "unprognostic (3.41e-2)" "unprognostic (1.98e-1)" "unprognostic (1.82e-1)" "unprognostic (3.13e-2)" "unprognostic (6.77e-3)" "unprognostic (1.15e-1)" "unprognostic (1.98e-3)" "unprognostic (2.47e-2)" "potential prognostic favorable (2.10e-5)" "unprognostic (3.81e-1)" "unprognostic (1.20e-1)" "unprognostic (2.59e-2)" "unprognostic (3.58e-1)" "unprognostic (2.93e-1)" "unprognostic (2.47e-2)" "unprognostic (9.38e-2)" "unprognostic (1.16e-1)" "potential prognostic favorable (2.17e-4)" "unprognostic (1.21e-2)" "unprognostic (1.18e-1)" "unprognostic (2.68e-1)" "unprognostic (3.15e-2)" "unprognostic (1.68e-1)" "unprognostic (4.14e-3)" "unprognostic (1.32e-1)" "unprognostic (2.56e-2)" "unprognostic (9.58e-3)" DTNB ENSG00000138101 "Dystrobrevin beta" O60941 2 25377198-25673647 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 24.4;salivary gland: 33.9" "Cell type enhanced" "Detected in many" "Hofbauer cells: 451.4;Lacrimal acinar cells: 627.7;Salivary acinar cells: 663.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Skin - Eccrine sweat gland cells, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "HPA047168, HPA061357" Uncertain Approved "Golgi apparatus" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 46 "Golgi apparatus" "HPA047168: , HPA061357: " "unprognostic (1.28e-2)" "unprognostic (2.96e-1)" "unprognostic (1.78e-1)" "unprognostic (7.01e-2)" "unprognostic (2.12e-2)" "unprognostic (1.77e-1)" "unprognostic (8.64e-2)" "unprognostic (1.65e-1)" "unprognostic (1.37e-1)" "unprognostic (7.32e-2)" "unprognostic (8.68e-2)" "unprognostic (4.66e-2)" "unprognostic (1.80e-1)" "potential prognostic unfavorable (6.23e-4)" "unprognostic (1.13e-1)" "unprognostic (1.20e-1)" "unprognostic (3.33e-2)" "unprognostic (6.27e-3)" "unprognostic (1.48e-2)" "unprognostic (1.45e-1)" "unprognostic (3.17e-1)" "unprognostic (5.05e-2)" "unprognostic (3.40e-2)" "unprognostic (5.50e-2)" "unprognostic (1.90e-1)" "unprognostic (6.13e-3)" "unprognostic (3.05e-1)" "unprognostic (1.09e-1)" "unprognostic (1.18e-1)" "unprognostic (3.35e-2)" "unprognostic (2.22e-1)" DTNBP1 "BLOC1S8, DBND, Dysbindin, HPS7, My031" ENSG00000047579 "Dystrobrevin binding protein 1" Q96EV8 6 15522807-15663058 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction" "Albinism, Hermansky-Pudlak syndrome, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 89.8;retina: 117.7" "Cell type enhanced" "Detected in all" "Retinal amacrine cells: 254.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028053, HPA029615, HPA029616" Approved Enhanced Microtubules,Midbody Yes No "Cluster 14: Non-specific - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 61 Microtubules Midbody "HPA028053: , HPA029615: , HPA029616: " "unprognostic (1.03e-1)" "unprognostic (1.29e-1)" "unprognostic (1.04e-1)" "unprognostic (8.42e-2)" "unprognostic (8.80e-2)" "unprognostic (8.93e-2)" "unprognostic (4.43e-2)" "unprognostic (1.55e-1)" "unprognostic (3.16e-2)" "unprognostic (1.60e-1)" "potential prognostic favorable (6.32e-4)" "unprognostic (7.94e-3)" "unprognostic (2.38e-1)" "potential prognostic unfavorable (4.12e-4)" "unprognostic (3.34e-3)" "unprognostic (7.11e-3)" "unprognostic (2.56e-1)" "unprognostic (8.44e-2)" "unprognostic (6.10e-2)" "unprognostic (2.02e-2)" "unprognostic (2.11e-1)" "unprognostic (1.25e-2)" "unprognostic (1.57e-1)" "unprognostic (3.16e-1)" "unprognostic (5.20e-2)" "unprognostic (2.06e-2)" "unprognostic (7.55e-2)" "unprognostic (1.36e-1)" "unprognostic (7.71e-2)" "unprognostic (5.41e-2)" "unprognostic (1.08e-1)" DTWD1 "MDS009, MGC111207" ENSG00000104047 "DTW domain containing 1" Q8N5C7 15 49621037-49656232 "Enzymes, Predicted intracellular proteins" "tRNA processing" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042214 Uncertain Approved "Nucleoplasm,Nucleoli rim,Mitotic chromosome,Vesicles" Yes No "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 55: Breast - Lactation" "Cluster 31: Non-specific - Transcription" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 7: Non-specific - Transcription" "Nucleoli rim" "Nucleoplasm, Mitotic chromosome, Vesicles" "HPA042214: " "unprognostic (7.23e-2)" "unprognostic (4.60e-1)" "unprognostic (2.81e-1)" "unprognostic (3.29e-3)" "unprognostic (1.31e-1)" "unprognostic (1.32e-1)" "unprognostic (1.27e-1)" "unprognostic (8.74e-2)" "unprognostic (8.45e-2)" "unprognostic (2.13e-3)" "potential prognostic favorable (1.96e-5)" "unprognostic (6.08e-3)" "unprognostic (3.58e-1)" "unprognostic (9.64e-2)" "unprognostic (2.43e-1)" "unprognostic (1.03e-1)" "unprognostic (7.32e-2)" "unprognostic (2.77e-1)" "unprognostic (6.86e-2)" "unprognostic (1.02e-1)" "unprognostic (2.06e-2)" "unprognostic (1.51e-3)" "unprognostic (6.25e-2)" "unprognostic (4.89e-1)" "unprognostic (2.35e-2)" "unprognostic (7.62e-2)" "unprognostic (5.69e-3)" "unprognostic (1.76e-1)" "unprognostic (1.49e-1)" "unprognostic (7.89e-3)" "unprognostic (2.91e-3)" DTWD2 FLJ33977 ENSG00000169570 "DTW domain containing 2" Q8NBA8 5 118836074-118988547 "Enzymes, Predicted intracellular proteins" "tRNA processing" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 214.0;Myonuclei: 211.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA053173, HPA054864" Approved Approved "Nuclear bodies" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 31: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 55: Myocytes - Oxidative muscle function" 5 "Nuclear bodies" "HPA053173: , HPA054864: " "potential prognostic favorable (6.27e-4)" "unprognostic (1.47e-1)" "unprognostic (2.89e-1)" "unprognostic (5.97e-2)" "unprognostic (1.27e-2)" "unprognostic (8.20e-3)" "unprognostic (5.82e-2)" "unprognostic (4.92e-2)" "unprognostic (3.11e-1)" "potential prognostic unfavorable (5.73e-4)" "potential prognostic favorable (1.19e-6)" "unprognostic (9.17e-2)" "unprognostic (5.27e-3)" "unprognostic (2.20e-1)" "unprognostic (1.26e-2)" "unprognostic (2.09e-1)" "unprognostic (3.51e-1)" "unprognostic (9.28e-2)" "unprognostic (7.41e-2)" "unprognostic (3.08e-3)" "potential prognostic unfavorable (2.30e-7)" "unprognostic (1.57e-2)" "unprognostic (4.33e-1)" "unprognostic (7.57e-2)" "unprognostic (6.60e-3)" "unprognostic (2.23e-1)" "unprognostic (1.40e-1)" "unprognostic (2.74e-1)" "unprognostic (2.36e-1)" "potential prognostic unfavorable (2.94e-4)" "unprognostic (1.01e-1)" DTX1 "hDx-1, RNF140" ENSG00000135144 "Deltex E3 ubiquitin ligase 1" Q86Y01 12 113056730-113098028 "Enzymes, Predicted intracellular proteins" "Notch signaling pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 8.9;lymphoid tissue: 11.7" "Cell type enriched" "Detected in many" 4 "Retinal horizontal cells: 338.6" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 7.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "lymphoma: 90.1" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Skeletal muscle - Fibroblasts, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051249, HPA055275" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 18: Lymphoid tissue - Immune response" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 109: Neurons - Neuronal signaling" 10 "Nucleoplasm, Cytosol" "Nuclear bodies" "HPA051249: , HPA055275: " "unprognostic (1.63e-2)" "unprognostic (1.80e-2)" "unprognostic (6.26e-2)" "unprognostic (3.89e-1)" "unprognostic (6.89e-2)" "unprognostic (1.18e-2)" "unprognostic (9.85e-3)" "unprognostic (7.61e-2)" "unprognostic (6.44e-2)" "unprognostic (1.35e-1)" "unprognostic (1.07e-1)" "unprognostic (5.72e-2)" "unprognostic (9.48e-2)" "unprognostic (8.74e-3)" "unprognostic (9.66e-2)" "unprognostic (1.80e-3)" DTX2 "KIAA1528, RNF58" ENSG00000091073 "Deltex E3 ubiquitin ligase 2" Q86UW9 7 76461676-76505995 "Enzymes, Predicted intracellular proteins" "Notch signaling pathway, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 51.1" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 35.4;Microglia: 34.6;Papillary tip epithelial cells: 53.3;Proximal tubule cells: 35.9;Renal collecting duct intercalated cells: 36.9;Sertoli cells: 41.5" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 42.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042931 Approved Supported "Nucleoplasm,Nuclear membrane,Vesicles,Plasma membrane,Cytosol" NA Yes "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 105: Non-specific - Mixed function" 129 "Nucleoplasm, Nuclear membrane" "Vesicles, Plasma membrane, Cytosol" "HPA042931: " "unprognostic (6.33e-2)" "unprognostic (2.81e-2)" "unprognostic (4.48e-2)" "unprognostic (1.18e-1)" "unprognostic (9.02e-2)" "unprognostic (8.14e-2)" "unprognostic (4.12e-2)" "unprognostic (1.62e-1)" "unprognostic (8.82e-2)" "unprognostic (1.37e-3)" "unprognostic (1.55e-1)" "unprognostic (2.77e-1)" "unprognostic (1.28e-2)" "potential prognostic unfavorable (4.02e-4)" "unprognostic (1.74e-3)" "unprognostic (6.69e-3)" "unprognostic (6.82e-2)" "unprognostic (1.55e-1)" "unprognostic (1.67e-1)" "unprognostic (3.60e-2)" "unprognostic (5.68e-2)" "unprognostic (3.97e-2)" "unprognostic (2.34e-2)" "unprognostic (4.29e-1)" "unprognostic (8.54e-2)" "unprognostic (9.32e-2)" "unprognostic (2.11e-1)" "unprognostic (3.62e-2)" "unprognostic (5.08e-1)" "unprognostic (1.27e-1)" "unprognostic (1.82e-1)" DTX3 "FLJ34766, RNF154" ENSG00000178498 "Deltex E3 ubiquitin ligase 3" Q8N9I9 12 57604622-57609804 "Enzymes, Predicted intracellular proteins" "Notch signaling pathway, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ependymal cells: 50.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 206.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 5 "NK-cells: 1.0;T-cells: 2.5" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059654 Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus" No No "Cluster 27: T-cells - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 53: Neurons - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 110: Mural cells - ECM organization" 40 "Nucleoplasm, Nucleoli" "Golgi apparatus" "HPA059654: " "unprognostic (1.19e-3)" "unprognostic (7.94e-2)" "unprognostic (6.53e-2)" "unprognostic (1.16e-1)" "unprognostic (2.27e-2)" "unprognostic (1.80e-1)" "unprognostic (4.55e-1)" "unprognostic (5.27e-3)" "unprognostic (4.32e-2)" "unprognostic (9.84e-2)" "unprognostic (6.44e-2)" "unprognostic (7.94e-2)" "unprognostic (1.24e-2)" "unprognostic (1.23e-1)" "unprognostic (1.51e-1)" "unprognostic (8.52e-2)" "unprognostic (1.87e-1)" "unprognostic (1.02e-3)" "unprognostic (5.04e-3)" "unprognostic (1.45e-1)" "unprognostic (2.10e-1)" "potential prognostic favorable (6.15e-4)" "unprognostic (1.02e-1)" "unprognostic (1.46e-1)" "unprognostic (1.08e-1)" "unprognostic (4.00e-2)" "unprognostic (6.15e-2)" "unprognostic (9.57e-2)" "unprognostic (1.45e-1)" "unprognostic (6.69e-2)" "unprognostic (1.47e-1)" DTX3L "BBAP, RNF143" ENSG00000163840 "Deltex E3 ubiquitin ligase 3L" Q8TDB6 3 122564338-122575203 "Enzymes, Predicted intracellular proteins" "Antiviral defense, DNA damage, DNA repair, Host-virus interaction, Immunity, Innate immunity, Protein transport, Transport, Ubl conjugation pathway" "Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 80.4" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 30.9;endothelial cell: 59.2;leukocyte: 40.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010570 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 13 "Nucleoplasm, Cytosol" "HPA010570: " "unprognostic (9.38e-3)" "unprognostic (8.29e-2)" "unprognostic (1.80e-1)" "unprognostic (5.29e-1)" "unprognostic (6.29e-2)" "unprognostic (2.66e-1)" "unprognostic (2.95e-1)" "unprognostic (1.03e-1)" "unprognostic (8.67e-2)" "unprognostic (5.66e-3)" "potential prognostic favorable (2.77e-4)" "unprognostic (7.73e-2)" "unprognostic (2.63e-2)" "unprognostic (9.45e-2)" "unprognostic (4.43e-2)" "unprognostic (2.00e-2)" "unprognostic (2.26e-2)" "unprognostic (2.19e-2)" "unprognostic (8.82e-2)" "unprognostic (1.55e-1)" "unprognostic (1.09e-1)" "potential prognostic unfavorable (5.43e-4)" "unprognostic (5.33e-2)" "unprognostic (5.06e-2)" "unprognostic (5.52e-2)" "unprognostic (2.73e-1)" "unprognostic (2.67e-1)" "unprognostic (7.42e-2)" "unprognostic (3.93e-2)" "unprognostic (1.43e-1)" "unprognostic (2.28e-1)" DTX4 "KIAA0937, RNF155" ENSG00000110042 "Deltex E3 ubiquitin ligase 4" Q9Y2E6 11 59171430-59208588 "Enzymes, Predicted intracellular proteins" "Notch signaling pathway, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 55.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 61.5;Oligodendrocytes: 49.4;Prostatic hillock cells: 42.9" "Cell type enhanced" "Detected in all" "oligodendrocyte: 91.5" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 90.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 2.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056760, HPA059294" Approved Approved Vesicles NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 69: Urothelial cells - Basic cellular functions" 2 Vesicles "HPA056760: , HPA059294: " "unprognostic (1.55e-2)" "unprognostic (5.15e-2)" "unprognostic (4.85e-1)" "unprognostic (2.43e-2)" "unprognostic (1.04e-1)" "unprognostic (7.88e-2)" "unprognostic (3.16e-2)" "unprognostic (6.46e-3)" "unprognostic (2.98e-1)" "unprognostic (1.53e-1)" "unprognostic (1.14e-2)" "unprognostic (1.29e-1)" "unprognostic (1.14e-1)" "unprognostic (3.84e-2)" "unprognostic (2.16e-1)" "unprognostic (2.15e-1)" "unprognostic (2.09e-2)" "unprognostic (3.24e-1)" "unprognostic (4.54e-2)" "unprognostic (3.40e-1)" "unprognostic (7.32e-2)" "unprognostic (2.80e-1)" "unprognostic (3.51e-1)" "potential prognostic favorable (7.52e-4)" "unprognostic (8.05e-3)" "unprognostic (3.52e-1)" "unprognostic (2.52e-2)" "unprognostic (2.84e-1)" "potential prognostic favorable (8.84e-4)" "unprognostic (3.36e-2)" DTYMK "CDC8, TMPK, TYMK" ENSG00000168393 "Deoxythymidylate kinase" P23919 2 241675747-241686944 "Disease related genes, Enzymes, Essential proteins, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotide biosynthesis" "Kinase, Transferase" "Disease variant, Intellectual disability, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enteric transient amplifying cells: 107.9;Erythrocyte progenitors: 127.1;Esophageal basal cells: 161.6;Extravillous trophoblasts: 172.4;Hofbauer cells: 102.2;Migrating cytotrophoblasts: 128.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042593, HPA042719" Approved Approved Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 6: Non-specific - Immune response" "Cluster 35: RS4;11 - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 6 Mitochondria "HPA042593: , HPA042719: " "unprognostic (1.69e-1)" "unprognostic (1.01e-1)" "unprognostic (2.84e-1)" "unprognostic (3.66e-1)" "unprognostic (2.81e-1)" "unprognostic (1.55e-2)" "unprognostic (3.44e-1)" "unprognostic (9.10e-3)" "unprognostic (7.78e-2)" "unprognostic (3.53e-2)" "validated prognostic unfavorable (2.35e-4)" "validated prognostic unfavorable (1.97e-4)" "unprognostic (3.35e-1)" "validated prognostic unfavorable (7.02e-7)" "validated prognostic unfavorable (2.23e-12)" "potential prognostic unfavorable (2.15e-5)" "unprognostic (2.22e-3)" "unprognostic (3.31e-2)" "unprognostic (2.08e-1)" "unprognostic (2.65e-1)" "unprognostic (4.54e-2)" "unprognostic (2.04e-3)" "unprognostic (3.78e-2)" "unprognostic (2.37e-1)" "unprognostic (4.68e-1)" "unprognostic (7.45e-3)" "unprognostic (2.36e-3)" "unprognostic (1.00e-1)" "unprognostic (3.31e-1)" "unprognostic (7.38e-2)" "unprognostic (3.21e-2)" DUOX1 "LNOX1, NOXEF1, THOX1" ENSG00000137857 "Dual oxidase 1" Q9NRD9 15 45129933-45165576 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrogen peroxide, Thyroid hormones biosynthesis" "Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 77.7;esophagus: 69.8;skin 1: 98.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 385.9;Alveolar cells type 2: 439.9;Endometrial luminal cells: 145.1;Esophageal apical cells: 454.2;Esophageal suprabasal cells: 236.1;Respiratory secretory cells: 163.1;Transitional alveolar cells: 282.7" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 81.3" "Region enriched" "Detected in all" 5 "cerebellum: 77.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 13.3;head and neck cancer: 15.4" "Breast - Breast myoepithelial cells, Colon - Enteric glia cells, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary gland basal cells, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Region enriched" "Detected in many" 5 "cerebellum: 13.5" HPA023544 Approved NA NA "Cluster 58: Skin - Keratinization" "Cluster 35: Non-specific - DNA binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 81: Alveolar cells - Lung function" 5 "HPA023544: " "unprognostic (2.29e-2)" "unprognostic (2.05e-2)" "unprognostic (6.51e-2)" "potential prognostic favorable (7.74e-4)" "unprognostic (1.45e-1)" "unprognostic (2.50e-1)" "unprognostic (3.00e-2)" "unprognostic (7.06e-3)" "unprognostic (1.15e-1)" "unprognostic (9.20e-2)" "unprognostic (1.34e-2)" "unprognostic (7.24e-2)" "unprognostic (5.25e-2)" "unprognostic (6.75e-2)" "unprognostic (1.94e-3)" "unprognostic (2.68e-3)" "unprognostic (7.59e-2)" "unprognostic (9.49e-2)" "unprognostic (1.59e-1)" "unprognostic (2.67e-1)" "unprognostic (2.08e-2)" "unprognostic (3.22e-2)" "unprognostic (2.59e-1)" "unprognostic (9.50e-3)" "unprognostic (2.12e-2)" "unprognostic (1.79e-1)" DUOX2 "LNOX2, P138-TOX, P138(TOX), THOX2" ENSG00000140279 "Dual oxidase 2" Q9NRD8 15 45092650-45114172 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Hydrogen peroxide, Thyroid hormones biosynthesis" "Oxidoreductase, Peroxidase" "Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 273.1;thyroid gland: 70.8;urinary bladder: 86.8" "Group enriched" "Detected in many" 5 "Conjunctival goblet cells: 322.3;Foveolar cells: 1151.8;Salivary duct cells: 383.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 137.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 1.9;Esophageal cancer: 2.2;head and neck cancer: 3.4" "Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Urothelial cells, Stomach - Gastric mucous cells, Thyroid gland - Thyroid glandular cells" "Region enhanced" "Detected in single" "basal ganglia: 1.2" "Not detected" "Not detected" NA NA "Cluster 13: Lung - Secretion" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 68: Foveolar cells - Mucosal defense" 1 "unprognostic (1.19e-1)" "unprognostic (2.03e-1)" "unprognostic (2.08e-1)" "unprognostic (8.54e-3)" "unprognostic (2.17e-2)" "unprognostic (6.01e-2)" "unprognostic (2.35e-3)" "unprognostic (2.71e-1)" "unprognostic (1.63e-2)" "unprognostic (1.53e-1)" "unprognostic (2.01e-2)" "unprognostic (1.61e-1)" "unprognostic (1.06e-1)" "unprognostic (7.76e-3)" "unprognostic (1.68e-1)" "unprognostic (4.54e-2)" DUOXA1 "FLJ32334, mol, NIP, NUMBIP" ENSG00000140254 "Dual oxidase maturation factor 1" Q1HG43 15 45117366-45129938 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 137.2;skin 1: 65.3;thyroid gland: 78.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 219.1;Alveolar cells type 2: 215.9;Endometrial luminal cells: 74.8;Esophageal apical cells: 387.6;Esophageal suprabasal cells: 179.5;Prostatic hillock cells: 69.8;Respiratory basal cells: 63.0;Respiratory deuterosomal cells: 64.3;Respiratory secretory cells: 76.7;Suprabasal keratinocytes: 99.9;Transitional alveolar cells: 155.1;Urothelial cells: 69.6" "Cell type enhanced" "Detected in some" "hippocampal dentate gyrus: 3.1" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 105.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bladder cancer: 8.0;cervical cancer: 9.9;Esophageal cancer: 9.7;head and neck cancer: 21.2" "Colon - Enteric glia cells, Minor Salivary Gland - Minor salivary gland basal cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA041578 Approved NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 81: Alveolar cells - Lung function" 1 "HPA041578: " "unprognostic (1.14e-1)" "unprognostic (1.96e-1)" "unprognostic (2.62e-1)" "unprognostic (8.69e-2)" "unprognostic (4.78e-2)" "unprognostic (9.27e-2)" "unprognostic (6.51e-3)" "unprognostic (5.73e-3)" "unprognostic (1.06e-2)" "unprognostic (2.09e-1)" "unprognostic (6.47e-2)" "unprognostic (1.35e-3)" "unprognostic (8.99e-2)" "unprognostic (1.58e-1)" "potential prognostic unfavorable (2.77e-4)" "unprognostic (3.84e-2)" "unprognostic (3.53e-1)" "unprognostic (9.57e-2)" "unprognostic (5.60e-2)" "unprognostic (1.38e-2)" "unprognostic (4.62e-2)" "unprognostic (1.23e-1)" "unprognostic (7.23e-2)" DUOXA2 ENSG00000140274 "Dual oxidase maturation factor 2" Q1HG44 15 45114326-45118421 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Protein transport, Transport" "Congenital hypothyroidism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "gallbladder: 60.1;urinary bladder: 39.0" "Cell type enhanced" "Detected in some" "Conjunctival goblet cells: 247.6;Esophageal apical cells: 56.4;Foveolar cells: 402.5;Pancreatic acinar cells: 77.8;Pancreatic duct cells: 132.4;Salivary duct cells: 248.8;Urothelial cells: 57.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Pancreatic Adenocarcinoma (TCGA): 56.4;Thyroid Carcinoma (TCGA): 46.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Urothelial cells, Stomach - Gastric mucous cells, Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA063548 Enhanced NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 68: Foveolar cells - Mucosal defense" 21 "HPA063548: " "unprognostic (2.27e-1)" "unprognostic (2.95e-1)" "unprognostic (9.35e-2)" "unprognostic (2.11e-2)" "unprognostic (1.40e-1)" "unprognostic (1.18e-1)" "unprognostic (1.87e-3)" "unprognostic (1.77e-1)" "unprognostic (3.48e-1)" "unprognostic (9.19e-3)" "unprognostic (3.28e-1)" "unprognostic (8.00e-2)" "unprognostic (1.20e-2)" "unprognostic (5.68e-2)" "unprognostic (1.02e-1)" DUS1L "DUS1, PP3111" ENSG00000169718 "Dihydrouridine synthase 1 like" Q6P1R4 17 82057506-82065887 "Enzymes, Predicted intracellular proteins" "tRNA processing" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 155.1;Late spermatids: 227.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Spleen - B-cells (Spleen), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023384 Uncertain Approved "Plasma membrane" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 24: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 17: Non-specific - RNA processing" 2 "Plasma membrane" "HPA023384: " "unprognostic (1.32e-1)" "unprognostic (3.89e-2)" "unprognostic (9.92e-2)" "unprognostic (1.05e-1)" "unprognostic (1.81e-1)" "unprognostic (2.29e-2)" "unprognostic (9.12e-3)" "unprognostic (1.60e-3)" "unprognostic (2.53e-1)" "unprognostic (1.25e-2)" "validated prognostic unfavorable (2.02e-5)" "validated prognostic unfavorable (2.07e-5)" "unprognostic (1.91e-1)" "unprognostic (1.85e-3)" "potential prognostic unfavorable (8.41e-4)" "unprognostic (1.91e-1)" "unprognostic (2.44e-1)" "unprognostic (1.89e-1)" "unprognostic (5.95e-2)" "unprognostic (4.45e-2)" "unprognostic (2.55e-3)" "unprognostic (6.76e-3)" "unprognostic (1.07e-1)" "unprognostic (1.04e-1)" "unprognostic (2.27e-2)" "unprognostic (1.30e-3)" "unprognostic (1.35e-2)" "unprognostic (5.91e-2)" "unprognostic (3.87e-1)" "unprognostic (3.78e-1)" "unprognostic (1.37e-1)" DUS2 "DUS2L, FLJ20399, SMM1" ENSG00000167264 "Dihydrouridine synthase 2" Q9NX74 16 67987746-68079320 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Oxidoreductase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 68.8;Myonuclei: 57.2;Neutrophils: 51.7;Retinal ganglion cells: 46.4;Syncytiotrophoblasts: 74.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042560, HPA043528" Enhanced Enhanced Cytosol NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 6: Non-specific - Immune response" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 3 Cytosol "HPA042560: , HPA043528: " "unprognostic (1.82e-1)" "unprognostic (2.33e-3)" "unprognostic (1.45e-2)" "unprognostic (2.15e-1)" "unprognostic (1.84e-1)" "unprognostic (5.26e-2)" "potential prognostic favorable (1.61e-5)" "unprognostic (1.86e-2)" "unprognostic (5.30e-2)" "potential prognostic favorable (2.07e-4)" "unprognostic (1.63e-1)" "unprognostic (3.01e-2)" "unprognostic (1.37e-3)" "unprognostic (3.43e-1)" "unprognostic (6.87e-2)" "unprognostic (2.51e-2)" "unprognostic (4.54e-2)" "unprognostic (2.44e-1)" "unprognostic (1.36e-1)" "unprognostic (1.98e-2)" "potential prognostic unfavorable (5.50e-5)" "unprognostic (2.08e-1)" "unprognostic (7.62e-2)" "unprognostic (2.18e-1)" "unprognostic (2.20e-1)" "unprognostic (4.09e-2)" "unprognostic (4.09e-2)" "unprognostic (3.01e-2)" "unprognostic (1.33e-1)" DUS3L "DUS3, FLJ13896" ENSG00000141994 "Dihydrouridine synthase 3 like" Q96G46 19 5784832-5791225 "Enzymes, Predicted intracellular proteins" "mRNA processing, tRNA processing" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 130.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041854, HPA041944, HPA062846" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 24: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 23: Non-specific - Transcription" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 5 Nucleoplasm Cytosol "HPA041854: , HPA041944: , HPA062846: " "unprognostic (2.18e-1)" "unprognostic (4.80e-2)" "unprognostic (1.82e-2)" "unprognostic (8.30e-2)" "unprognostic (9.70e-2)" "unprognostic (4.80e-2)" "unprognostic (1.89e-1)" "unprognostic (8.09e-2)" "unprognostic (1.23e-2)" "unprognostic (7.00e-2)" "unprognostic (1.11e-1)" "unprognostic (3.04e-1)" "unprognostic (1.90e-1)" "unprognostic (1.73e-1)" "unprognostic (5.00e-2)" "unprognostic (1.48e-1)" "unprognostic (2.85e-2)" "unprognostic (1.06e-1)" "unprognostic (3.09e-2)" "unprognostic (9.32e-2)" "unprognostic (4.09e-2)" "unprognostic (6.73e-3)" "unprognostic (9.59e-2)" "unprognostic (2.31e-3)" "unprognostic (8.95e-2)" "unprognostic (1.38e-3)" "unprognostic (4.29e-2)" "unprognostic (2.42e-2)" "unprognostic (2.12e-1)" "unprognostic (1.16e-1)" "unprognostic (4.37e-2)" DUS4L "DUS4, PP35" ENSG00000105865 "Dihydrouridine synthase 4 like" O95620 7 107563484-107578523 "Enzymes, Predicted intracellular proteins" "tRNA processing" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 7.8;Bergmann glia: 7.3;Brain excitatory neurons: 6.4;Brain inhibitory neurons: 8.7;Choroid plexus epithelial cells: 5.7;Distal convoluted tubule cells: 11.2;Ependymal cells: 7.8;Late spermatids: 5.6;Loop of henle epithelial cells: 7.6;Microglia: 7.3;Oligodendrocyte progenitor cells: 7.0;Oligodendrocytes: 12.5;Other brain neurons: 8.8;Papillary tip epithelial cells: 7.5;Podocytes: 8.3;Proximal tubule cells: 8.2;Renal collecting duct intercalated cells: 10.5;Renal collecting duct principal cells: 9.7;Renal connecting tubule cells: 6.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044301 Approved Approved Cytosol NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 102: Non-specific - Mixed function" Cytosol "HPA044301: " "unprognostic (8.06e-2)" "unprognostic (6.98e-3)" "unprognostic (7.94e-2)" "unprognostic (8.09e-3)" "unprognostic (7.24e-2)" "potential prognostic unfavorable (5.25e-4)" "unprognostic (3.40e-2)" "unprognostic (1.65e-1)" "unprognostic (1.17e-3)" "unprognostic (1.28e-2)" "unprognostic (1.16e-1)" "unprognostic (4.43e-2)" "unprognostic (7.04e-3)" "potential prognostic unfavorable (3.51e-4)" "unprognostic (2.28e-3)" "unprognostic (7.75e-2)" "unprognostic (4.36e-2)" "unprognostic (1.35e-1)" "unprognostic (2.42e-2)" "unprognostic (1.33e-1)" "unprognostic (5.43e-2)" "unprognostic (4.07e-2)" "unprognostic (8.84e-2)" "unprognostic (1.56e-2)" "unprognostic (3.66e-2)" "unprognostic (2.11e-1)" "unprognostic (1.93e-2)" "unprognostic (1.20e-3)" "unprognostic (6.11e-2)" DUS4L-BCAP29 ENSG00000288558 "DUS4L-BCAP29 readthrough" 7 107563971-107623317 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Early spermatids: 1.1;Gastric chief cells: 1.1;Late spermatids: 1.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "HPA029215, HPA044301, HPA049694" Approved Approved Cytosol NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" Cytosol "HPA029215: , HPA044301: , HPA049694: " "unprognostic (5.84e-2)" "unprognostic (2.75e-1)" "unprognostic (9.24e-2)" "unprognostic (8.12e-2)" "unprognostic (6.24e-2)" "unprognostic (9.01e-2)" "unprognostic (2.11e-1)" "unprognostic (5.97e-2)" "unprognostic (8.53e-2)" "unprognostic (6.50e-2)" "unprognostic (5.70e-2)" "unprognostic (3.87e-3)" "unprognostic (7.63e-2)" "unprognostic (7.23e-2)" "unprognostic (3.47e-1)" "unprognostic (5.02e-1)" "unprognostic (1.63e-1)" "unprognostic (3.62e-2)" "unprognostic (2.09e-1)" "unprognostic (7.85e-2)" "unprognostic (2.66e-2)" "unprognostic (2.89e-1)" "unprognostic (5.14e-3)" "unprognostic (1.19e-2)" "unprognostic (2.46e-2)" "unprognostic (1.40e-1)" DUSP1 "CL100, HVH1, MKP-1, PTPN10" ENSG00000120129 "Dual specificity phosphatase 1" P28562 5 172768096-172771195 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Cell cycle, Stress response" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 3856.7;monocytes: 2271.8;Neutrophils: 6470.4;Smooth muscle cells: 2354.6" "Cell type enhanced" "Detected in all" "endothelial cell: 653.9;vascular associated smooth muscle cell: 402.9" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 762.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "neutrophil: 7452.7" "Lineage enriched" "Detected in all" 9 "granulocytes: 7452.7" "Low cancer specificity" "Detected in all" "Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069577 Approved Nucleoli,Cytosol NA Yes "Cluster 35: Neutrophils - Protein binding" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 12: Non-specific - Vasculature" "Cluster 72: Neuronal - Signal transduction" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 19 Nucleoli Cytosol "HPA069577: " "unprognostic (2.41e-2)" "unprognostic (1.47e-1)" "unprognostic (4.00e-2)" "unprognostic (7.88e-2)" "unprognostic (1.83e-2)" "unprognostic (5.00e-2)" "unprognostic (1.18e-1)" "unprognostic (2.63e-3)" "unprognostic (1.65e-2)" "unprognostic (9.76e-2)" "potential prognostic favorable (3.64e-4)" "unprognostic (2.80e-2)" "unprognostic (2.79e-1)" "unprognostic (8.45e-2)" "unprognostic (1.71e-2)" "unprognostic (8.15e-2)" "unprognostic (1.51e-1)" "unprognostic (5.89e-3)" "unprognostic (3.48e-1)" "unprognostic (3.89e-3)" "unprognostic (2.55e-1)" "unprognostic (2.44e-1)" "unprognostic (1.10e-2)" "unprognostic (5.86e-2)" "unprognostic (1.60e-1)" "unprognostic (1.11e-3)" "unprognostic (2.20e-1)" "potential prognostic unfavorable (1.22e-5)" "unprognostic (1.59e-1)" "unprognostic (1.35e-2)" "unprognostic (1.39e-1)" DUSP10 "MKP-5, MKP5" ENSG00000143507 "Dual specificity phosphatase 10" Q9Y6W6 1 221701424-221742089 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 30.8" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 126.3;Mast cells: 210.8;Salivary ionocytes: 171.2" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 238.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 19.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016758 Approved Supported Nucleoplasm,Cytosol No No "Cluster 33: Non-specific - ATP binding" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 11: White matter - Signal transduction" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 15 "Nucleoplasm, Cytosol" "HPA016758: " "unprognostic (2.00e-1)" "unprognostic (1.17e-1)" "unprognostic (2.56e-2)" "unprognostic (4.88e-2)" "unprognostic (2.21e-1)" "unprognostic (2.24e-2)" "unprognostic (8.35e-2)" "unprognostic (5.45e-2)" "unprognostic (4.28e-3)" "unprognostic (2.93e-1)" "unprognostic (7.95e-2)" "unprognostic (1.06e-1)" "unprognostic (1.49e-1)" "unprognostic (5.03e-3)" "potential prognostic favorable (9.48e-5)" "unprognostic (1.23e-1)" "unprognostic (8.61e-2)" "unprognostic (9.85e-2)" "unprognostic (9.55e-2)" "unprognostic (2.15e-1)" "unprognostic (2.03e-1)" "potential prognostic unfavorable (3.87e-4)" "unprognostic (1.31e-2)" "unprognostic (1.89e-1)" "unprognostic (4.23e-2)" "unprognostic (5.69e-3)" "unprognostic (6.02e-3)" "unprognostic (1.19e-1)" "unprognostic (1.25e-1)" "unprognostic (3.07e-3)" "unprognostic (2.34e-1)" DUSP11 PIR1 ENSG00000144048 "Dual specificity phosphatase 11" O75319 2 73761782-73780132 "Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 217.9;Oocytes: 124.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021052 Supported "Nucleoplasm,Nucleoli fibrillar center,Cytokinetic bridge" Yes Yes "Cluster 3: Non-specific - Nuclear processes" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 9: Non-specific - Receptor signaling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 26: Keratinocytes - Keratinization" 4 "Nucleoplasm, Nucleoli fibrillar center" "Cytokinetic bridge" "HPA021052: " "unprognostic (2.07e-2)" "unprognostic (2.03e-1)" "unprognostic (9.61e-2)" "unprognostic (2.09e-1)" "unprognostic (3.73e-2)" "unprognostic (4.74e-1)" "unprognostic (1.07e-1)" "unprognostic (4.41e-2)" "unprognostic (9.24e-3)" "unprognostic (5.33e-2)" "potential prognostic favorable (8.79e-6)" "unprognostic (2.08e-2)" "unprognostic (1.59e-1)" "potential prognostic unfavorable (4.43e-8)" "unprognostic (3.10e-3)" "unprognostic (2.75e-2)" "unprognostic (1.95e-3)" "unprognostic (1.51e-2)" "unprognostic (1.07e-1)" "unprognostic (2.59e-1)" "unprognostic (2.29e-2)" "unprognostic (2.31e-2)" "unprognostic (2.04e-3)" "unprognostic (3.48e-2)" "unprognostic (7.25e-2)" "unprognostic (2.45e-1)" "unprognostic (2.08e-2)" "unprognostic (3.15e-1)" "unprognostic (5.01e-1)" "unprognostic (1.79e-1)" "unprognostic (2.02e-1)" DUSP12 "DUSP1, YVH1" ENSG00000081721 "Dual specificity phosphatase 12" Q9UNI6 1 161749758-161757238 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008840 Uncertain Supported Nucleoplasm NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 15: Bone marrow - Innate immune response" "Cluster 55: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 97: Non-specific - Cellular respiration" 9 Nucleoplasm "HPA008840: " "unprognostic (2.97e-3)" "unprognostic (1.13e-2)" "unprognostic (1.13e-2)" "unprognostic (1.35e-1)" "unprognostic (1.35e-1)" "unprognostic (1.77e-1)" "unprognostic (1.10e-2)" "unprognostic (5.74e-2)" "unprognostic (1.47e-1)" "unprognostic (1.01e-2)" "unprognostic (2.26e-1)" "unprognostic (1.20e-1)" "unprognostic (1.47e-1)" "potential prognostic unfavorable (2.83e-6)" "unprognostic (2.64e-2)" "unprognostic (3.00e-2)" "unprognostic (7.00e-2)" "unprognostic (2.73e-1)" "unprognostic (5.74e-2)" "unprognostic (6.62e-2)" "unprognostic (2.92e-1)" "unprognostic (8.53e-2)" "unprognostic (8.96e-3)" "unprognostic (3.19e-3)" "unprognostic (5.54e-2)" "unprognostic (1.27e-1)" "unprognostic (2.69e-2)" "unprognostic (3.72e-2)" "unprognostic (2.56e-1)" "potential prognostic unfavorable (4.08e-4)" "unprognostic (6.18e-2)" DUSP13 "BEDP, DUSP13A, DUSP13B, FLJ32450, MDSP, TMDP" ENSG00000079393 "Dual specificity phosphatase 13" "Q6B8I1, Q9UII6" 10 75094432-75109221 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skeletal muscle: 240.9;testis: 50.8;tongue: 104.0" "Cell type enhanced" "Detected in some" "Early spermatids: 441.8;Late primary spermatocytes: 265.8;Late spermatids: 83.1;Myonuclei: 140.7;Thymic myoid cells: 35.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Lung Adenocarcinoma (TCGA): 2.1" "Region enhanced" "Detected in single" "pons: 3.2" "Immune cell enriched" "Detected in single" 14 "neutrophil: 1.4" "Lineage enriched" "Detected in single" 14 "granulocytes: 1.4" "Cancer enhanced" "Detected in some" "Sarcoma: 3.6" "Heart muscle - Cardiomyocytes, Lung - Neutrophils_1, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 14 "unprognostic (1.62e-1)" "unprognostic (1.13e-3)" "unprognostic (1.46e-1)" DUSP14 "MKP-L, MKP6" ENSG00000276023 "Dual specificity phosphatase 14" O95147 17 37489891-37513501 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 44.5" "Cell type enhanced" "Detected in some" "Astrocytes: 4.9;Bergmann glia: 5.1;Brain excitatory neurons: 13.3;Brain inhibitory neurons: 12.2;Choroid plexus epithelial cells: 16.1;Ependymal cells: 27.7;Late spermatids: 3.9;Loop of henle epithelial cells: 4.6;Other brain neurons: 12.1;Podocytes: 7.2;Renal collecting duct intercalated cells: 4.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 1.6" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 8 "Bile duct cancer: 40.2;testis cancer: 23.0" "Skin - Hair cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019911 Approved Approved Nucleoplasm,Cytosol NA Yes "Cluster 35: Neutrophils - Protein binding" "Cluster 2: Non-specific - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 34: Ciliated cells - Cilia assembly & function" 31 "Nucleoplasm, Cytosol" "HPA019911: " "unprognostic (4.29e-2)" "unprognostic (8.47e-2)" "unprognostic (5.21e-1)" "unprognostic (1.35e-1)" "unprognostic (8.64e-2)" "unprognostic (4.30e-2)" "unprognostic (1.89e-2)" "unprognostic (1.39e-1)" "unprognostic (1.65e-2)" "potential prognostic unfavorable (1.47e-4)" "unprognostic (8.37e-2)" "unprognostic (3.52e-2)" "unprognostic (1.25e-3)" "potential prognostic unfavorable (8.11e-4)" "unprognostic (4.49e-1)" "unprognostic (2.94e-2)" "potential prognostic favorable (8.45e-5)" "unprognostic (2.53e-1)" "unprognostic (1.92e-2)" "unprognostic (1.52e-1)" "unprognostic (1.02e-1)" "unprognostic (2.74e-2)" "unprognostic (1.42e-1)" "unprognostic (7.89e-2)" "unprognostic (1.26e-1)" "unprognostic (1.55e-1)" DUSP15 "bA243J16.5, bA243J16.6, C20orf57, FLJ20645, VHY" ENSG00000149599 "Dual specificity phosphatase 15" Q9H1R2 20 31847637-31870664 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "testis: 208.8" "Cell type enriched" "Detected in many" 4 "Late spermatids: 1777.2" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in many" 10 "Kidney Chromophobe (TCGA): 144.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 7.4" "Breast - Breast glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076649 Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 67: Testis - Mixed function" "Cluster 30: White matter - Myelination" "Cluster 11: Neuronal - Sensory perception" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 1 "Plasma membrane, Cytosol" "HPA076649: " "unprognostic (1.93e-2)" "unprognostic (6.30e-2)" "unprognostic (5.54e-2)" "unprognostic (7.96e-3)" "unprognostic (4.56e-1)" "unprognostic (5.80e-2)" "unprognostic (3.24e-2)" "unprognostic (4.62e-2)" "unprognostic (1.72e-1)" "unprognostic (4.31e-1)" "unprognostic (1.25e-1)" "potential prognostic favorable (4.44e-5)" "unprognostic (4.37e-2)" "unprognostic (8.92e-2)" "unprognostic (2.22e-1)" "potential prognostic favorable (2.35e-5)" "unprognostic (4.64e-2)" "unprognostic (2.23e-1)" "unprognostic (7.98e-3)" "unprognostic (2.68e-1)" "unprognostic (3.59e-3)" "unprognostic (2.43e-1)" "potential prognostic unfavorable (4.65e-4)" "unprognostic (2.87e-3)" DUSP16 "KIAA1700, MKP-7, MKP7" ENSG00000111266 "Dual specificity phosphatase 16" Q9BY84 12 12473282-12562863 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 49.2;Bergmann glia: 74.3;Choroid plexus epithelial cells: 122.3;Distal convoluted tubule cells: 53.6;Ependymal cells: 51.7;Loop of henle epithelial cells: 54.2;Microglia: 90.3;Oligodendrocyte progenitor cells: 98.3;Oligodendrocytes: 217.5;Papillary tip epithelial cells: 143.0;Podocytes: 116.1;Proximal tubule cells: 73.6;Renal collecting duct intercalated cells: 67.9;Renal collecting duct principal cells: 68.6;Renal connecting tubule cells: 81.8" "Cell type enhanced" "Detected in all" "oligodendrocyte: 258.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 3.9" "Lineage enriched" "Detected in single" 5 "T-cells: 3.9" "Cancer enhanced" "Detected in all" "Bile duct cancer: 49.6" "Adrenal gland - Adrenal cortex cells, Prostate - Prostate glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020326 Approved Supported Nucleoplasm NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 76: Non-specific - Metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 38: Non-specific - Transcription" "Cluster 102: Non-specific - Mixed function" 17 Nucleoplasm "HPA020326: " "potential prognostic favorable (1.88e-4)" "unprognostic (1.55e-1)" "unprognostic (1.60e-1)" "unprognostic (6.09e-2)" "unprognostic (9.11e-3)" "unprognostic (2.96e-2)" "unprognostic (2.06e-1)" "unprognostic (3.12e-2)" "unprognostic (2.34e-3)" "unprognostic (1.98e-1)" "potential prognostic favorable (1.21e-6)" "unprognostic (4.88e-3)" "unprognostic (2.42e-2)" "unprognostic (1.03e-1)" "unprognostic (3.59e-1)" "unprognostic (8.81e-2)" "unprognostic (3.95e-1)" "unprognostic (6.72e-2)" "unprognostic (3.96e-2)" "unprognostic (7.71e-2)" "unprognostic (2.87e-1)" "unprognostic (8.06e-2)" "unprognostic (2.02e-1)" "unprognostic (1.73e-1)" "unprognostic (4.98e-3)" "unprognostic (5.53e-3)" "unprognostic (9.69e-2)" "unprognostic (1.81e-2)" "unprognostic (2.32e-1)" "unprognostic (6.08e-2)" "unprognostic (1.30e-1)" DUSP18 DUSP20 ENSG00000167065 "Dual specificity phosphatase 18" Q8NEJ0 22 30652051-30667887 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 225.7;Early spermatids: 143.8;Ependymal cells: 111.9;Fallopian tube ciliated cells: 97.6;Late primary spermatocytes: 119.8;Late spermatids: 643.9;Respiratory ciliated cells: 173.2" "Cell type enhanced" "Detected in all" "ependymal cell: 126.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034070, HPA051349" Uncertain Supported Nucleoplasm Yes No "Cluster 42: Non-specific - Vesicular transport" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 5 Nucleoplasm "CAB034070: , HPA051349: " "unprognostic (4.93e-2)" "unprognostic (1.26e-1)" "unprognostic (1.43e-1)" "unprognostic (1.58e-2)" "unprognostic (2.07e-2)" "unprognostic (6.40e-2)" "unprognostic (1.42e-1)" "unprognostic (4.91e-2)" "unprognostic (7.95e-2)" "unprognostic (2.73e-1)" "unprognostic (2.41e-2)" "unprognostic (1.90e-1)" "unprognostic (3.02e-1)" "unprognostic (3.45e-1)" "unprognostic (2.96e-1)" "unprognostic (5.75e-2)" "unprognostic (2.55e-2)" "unprognostic (3.24e-2)" "unprognostic (1.63e-1)" "unprognostic (9.47e-2)" "unprognostic (8.96e-2)" "unprognostic (4.18e-1)" "unprognostic (3.72e-1)" "potential prognostic favorable (8.13e-4)" "unprognostic (2.92e-1)" "unprognostic (1.34e-1)" "unprognostic (4.74e-2)" "unprognostic (3.98e-2)" "unprognostic (2.53e-2)" "unprognostic (4.63e-2)" DUSP19 "DUSP17, SKRP1" ENSG00000162999 "Dual specificity phosphatase 19" Q8WTR2 2 183078559-183100008 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fallopian tube ciliated cells: 28.7;Late primary spermatocytes: 32.2;Megakaryocytes: 24.7;Parietal cells: 109.6;Respiratory ciliated cells: 26.9" "Cell type enhanced" "Detected in all" "hippocampal CA4: 49.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Stomach - Parietal cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021501 Approved Approved Nucleoplasm Yes No "Cluster 43: Non-specific - Transcription & Translation" "Cluster 61: Non-specific - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 97: Non-specific - Cellular respiration" 7 Nucleoplasm "HPA021501: " "unprognostic (1.30e-2)" "unprognostic (8.68e-2)" "unprognostic (2.78e-2)" "unprognostic (1.19e-1)" "unprognostic (2.66e-1)" "unprognostic (1.35e-1)" "unprognostic (3.05e-3)" "unprognostic (6.64e-2)" "unprognostic (1.65e-3)" "unprognostic (2.12e-2)" "unprognostic (4.48e-1)" "unprognostic (2.52e-2)" "unprognostic (1.94e-1)" "unprognostic (3.13e-2)" "unprognostic (6.20e-2)" "unprognostic (9.39e-2)" "unprognostic (5.93e-2)" "unprognostic (1.01e-1)" "unprognostic (2.88e-1)" "unprognostic (1.70e-2)" "unprognostic (6.03e-2)" "unprognostic (5.79e-2)" "unprognostic (9.28e-2)" "unprognostic (2.26e-1)" DUSP2 PAC-1 ENSG00000158050 "Dual specificity phosphatase 2" Q05923 2 96143169-96145440 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 122.1" "Cell type enhanced" "Detected in many" "Breast secretory cells: 224.0;cDC: 607.2;Endometrial glandular cells: 357.8;Endometrial luminal cells: 263.3;Epididymal basal cells: 325.3;Epididymal principal cells: 497.3;Innate lymphoid cells: 538.1;monocytes: 338.0;NK-cells: 662.5;Plasma cells: 223.7;T-cells: 613.2;Urothelial cells: 286.0" "Cell type enriched" "Detected in many" 20 "leukocyte: 153.8" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebral cortex: 93.1" "Immune cell enhanced" "Detected in all" "gdT-cell: 199.8" "Group enriched" "Detected in all" 10 "NK-cells: 148.3;T-cells: 199.8" "Cancer enriched" "Detected in many" 5 "lymphoma: 83.5" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Thyroid gland - T-cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA071920 Supported "Nucleoplasm,Nuclear membrane" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 29: Forebrain - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 4 "Nuclear membrane" Nucleoplasm "HPA071920: " "unprognostic (6.71e-2)" "unprognostic (6.43e-2)" "unprognostic (5.63e-2)" "unprognostic (2.94e-2)" "unprognostic (2.46e-1)" "unprognostic (1.17e-1)" "unprognostic (3.31e-2)" "unprognostic (1.94e-1)" "unprognostic (1.53e-1)" "unprognostic (3.76e-1)" "unprognostic (7.04e-3)" "unprognostic (8.01e-2)" "unprognostic (1.62e-1)" "unprognostic (2.29e-1)" "unprognostic (5.93e-2)" "unprognostic (9.38e-3)" "unprognostic (1.42e-1)" "unprognostic (1.86e-1)" "unprognostic (3.04e-1)" "unprognostic (2.89e-2)" "unprognostic (5.85e-2)" "unprognostic (2.57e-1)" "unprognostic (3.83e-2)" "unprognostic (9.84e-2)" "unprognostic (2.76e-1)" "potential prognostic favorable (1.66e-4)" "unprognostic (3.49e-1)" "unprognostic (3.71e-1)" "unprognostic (7.95e-2)" "unprognostic (8.85e-2)" "unprognostic (3.95e-1)" DUSP21 ENSG00000189037 "Dual specificity phosphatase 21" Q9H596 X 44844021-44844888 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 42 "testis: 10.2" "Cell type enriched" "Detected in some" 5 "Late spermatids: 518.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" HPA059171 Approved "Nucleoli,Centrosome,Connecting piece,Mid piece,Principal piece" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 47: Leukemia - Hemostasis" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 17 Centrosome "Nucleoli, Connecting piece, Mid piece, Principal piece" "HPA059171: " DUSP22 "JKAP, JSP1, MKPX, VHX" ENSG00000112679 "Dual specificity phosphatase 22" Q9NRW4 6 291630-351355 "Enzymes, Human disease related genes, Predicted intracellular proteins" Immunity "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 284.9;Esophageal suprabasal cells: 176.9;Oocytes: 216.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Myeloma: 134.6" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031394 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 85: Squamous epithelial cells - Keratinization" 3 "Nucleoplasm, Vesicles" "HPA031394: " "unprognostic (1.91e-2)" "unprognostic (2.78e-2)" "unprognostic (3.67e-1)" "unprognostic (4.66e-2)" "unprognostic (4.10e-3)" "potential prognostic unfavorable (3.73e-4)" "unprognostic (1.72e-1)" "unprognostic (1.11e-1)" "unprognostic (1.84e-1)" "unprognostic (6.54e-2)" "potential prognostic favorable (8.07e-5)" "unprognostic (4.57e-2)" "unprognostic (1.28e-1)" "unprognostic (3.32e-3)" "unprognostic (2.29e-2)" "unprognostic (4.07e-2)" "unprognostic (8.77e-2)" "unprognostic (2.04e-3)" "unprognostic (1.87e-1)" "unprognostic (4.34e-2)" "unprognostic (2.40e-1)" "unprognostic (1.56e-1)" "unprognostic (2.14e-1)" "unprognostic (4.08e-1)" "unprognostic (2.01e-2)" "unprognostic (3.78e-1)" "unprognostic (1.29e-1)" "unprognostic (1.36e-1)" "unprognostic (3.17e-2)" "unprognostic (6.34e-3)" "unprognostic (1.99e-1)" DUSP23 "DUSP25, FLJ20442" ENSG00000158716 "Dual specificity phosphatase 23" Q9BVJ7 1 159780932-159782543 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal efferent duct absorptive cells: 249.7;Esophageal suprabasal cells: 257.2;Hepatocytes: 261.4;Oocytes: 327.0;Salivary acinar cells: 279.7;Submucosal glandular cells: 292.2" "Cell type enhanced" "Detected in many" "endothelial cell: 29.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028211, HPA045792" Approved Supported Nucleoplasm NA NA 15000 "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 9 Nucleoplasm "HPA028211: , HPA045792: " "unprognostic (6.74e-2)" "unprognostic (1.32e-1)" "unprognostic (1.75e-1)" "unprognostic (1.23e-1)" "unprognostic (5.42e-2)" "unprognostic (2.25e-1)" "unprognostic (1.28e-2)" "potential prognostic unfavorable (5.74e-4)" "unprognostic (8.29e-2)" "unprognostic (3.84e-2)" "potential prognostic unfavorable (4.55e-5)" "unprognostic (7.32e-2)" "unprognostic (1.24e-1)" "potential prognostic unfavorable (1.66e-5)" "unprognostic (1.08e-2)" "unprognostic (7.39e-2)" "unprognostic (6.63e-2)" "unprognostic (1.76e-1)" "unprognostic (2.78e-1)" "unprognostic (1.30e-1)" "unprognostic (2.32e-2)" "unprognostic (4.67e-2)" "unprognostic (1.59e-2)" "unprognostic (4.70e-2)" "unprognostic (3.33e-2)" "unprognostic (8.58e-3)" "unprognostic (1.74e-1)" "unprognostic (5.71e-2)" "unprognostic (3.82e-2)" "unprognostic (1.05e-1)" "unprognostic (4.50e-2)" DUSP26 "DUSP24, MGC1136, NEAP" ENSG00000133878 "Dual specificity phosphatase 26" Q9BV47 8 33591330-33600023 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 394.8;tongue: 190.8" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 22.8;Brain inhibitory neurons: 24.9;Cone photoreceptor cells: 35.2;Corticotrophs: 43.8;Lactotrophs: 29.7;Myonuclei: 53.6;Neuroendocrine cells: 23.3;Other brain neurons: 39.7;Pancreatic islet cells: 51.5;Retinal amacrine cells: 24.8;Retinal bipolar cells: 52.8;Rod photoreceptor cells: 48.5;Somatotrophs: 29.0;Thymic myoid cells: 74.8;Thyrotrophs: 24.6" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 14.2;Pancreatic Adenocarcinoma (TCGA): 8.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 8.8;Neuroblastoma: 28.5" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Kidney - Ascending Loop of Henle cells, Pancreas - Alpha cells, Pancreas - Beta cells, Prostate - Fibroblasts, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018221 Approved Supported Nucleoplasm NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 79: Photoreceptor cells - Phototransduction" 10 Nucleoplasm "HPA018221: " "unprognostic (2.31e-3)" "unprognostic (1.53e-1)" "potential prognostic favorable (1.31e-4)" "unprognostic (7.75e-2)" "unprognostic (1.89e-3)" "unprognostic (2.84e-3)" "unprognostic (2.56e-1)" "unprognostic (8.67e-3)" "unprognostic (1.09e-1)" "unprognostic (6.40e-2)" DUSP28 "DUSP26, VHP" ENSG00000188542 "Dual specificity phosphatase 28" Q4G0W2 2 240560054-240565256 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 55.0;Early primary spermatocytes: 35.8;Early spermatids: 39.8;Late primary spermatocytes: 49.0;Late spermatids: 52.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 8.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 8.8" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Prostate - Prostate basal glandular cells, Skeletal muscle - Skeletal myocytes, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047456, CAB069448" Uncertain Uncertain "Nuclear speckles,Cytosol" NA NA "Cluster 32: Basophils - Transcription" "Cluster 24: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 56: Non-specific - Sensory perception" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "Nuclear speckles" Cytosol "CAB069448: , HPA047456: " "unprognostic (8.87e-3)" "unprognostic (1.26e-1)" "unprognostic (3.70e-2)" "unprognostic (6.66e-3)" "unprognostic (1.39e-2)" "unprognostic (2.31e-1)" "unprognostic (3.05e-1)" "unprognostic (8.73e-2)" "unprognostic (1.16e-1)" "potential prognostic unfavorable (3.82e-5)" "unprognostic (3.34e-3)" "unprognostic (1.35e-2)" "unprognostic (8.30e-3)" "unprognostic (7.98e-2)" "unprognostic (1.62e-1)" "unprognostic (1.36e-1)" "potential prognostic favorable (1.08e-4)" "unprognostic (3.38e-2)" "unprognostic (3.19e-1)" "potential prognostic favorable (1.40e-4)" "unprognostic (2.19e-1)" "unprognostic (6.89e-2)" "unprognostic (7.75e-2)" "unprognostic (1.67e-1)" "potential prognostic unfavorable (1.29e-4)" "unprognostic (6.85e-2)" "unprognostic (2.96e-1)" "unprognostic (1.40e-1)" "unprognostic (4.28e-2)" DUSP29 "DUPD1, DUSP27" ENSG00000188716 "Dual specificity phosphatase 29" Q68J44 10 75037472-75073642 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "skeletal muscle: 97.3" "Cell type enriched" "Detected in single" 8 "Myonuclei: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pituitary gland - Gonadotropes" "Not detected" "Not detected" "Not detected" "Not detected" HPA042964 Uncertain NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 27: Breast cancer - Unknown function" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 16 "HPA042964: " DUSP3 VHR ENSG00000108861 "Dual specificity phosphatase 3" P51452 17 43766125-43778977 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 245.3" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 200.2;Hepatocytes: 121.3;Hofbauer cells: 143.1;Late spermatids: 287.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 9 "dendritic cells: 33.5;granulocytes: 10.9;monocytes: 29.4" "Low cancer specificity" "Detected in all" "Colon - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" HPA073671 Supported Nucleoplasm,Cytosol NA NA 1500000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 14: Neurons - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 17: Non-specific - RNA processing" 14 Nucleoplasm Cytosol "HPA073671: " "unprognostic (4.11e-2)" "unprognostic (2.27e-1)" "unprognostic (1.24e-1)" "unprognostic (6.03e-2)" "unprognostic (1.76e-1)" "unprognostic (2.60e-2)" "unprognostic (1.52e-3)" "unprognostic (1.73e-1)" "potential prognostic unfavorable (8.82e-4)" "unprognostic (7.57e-2)" "potential prognostic favorable (2.24e-5)" "unprognostic (5.16e-2)" "unprognostic (9.50e-3)" "unprognostic (7.39e-2)" "unprognostic (4.24e-1)" "unprognostic (1.75e-1)" "unprognostic (8.24e-2)" "unprognostic (4.66e-2)" "unprognostic (2.24e-1)" "unprognostic (5.73e-2)" "potential prognostic unfavorable (4.60e-4)" "unprognostic (9.66e-2)" "unprognostic (1.61e-1)" "unprognostic (1.45e-1)" "unprognostic (3.48e-2)" "unprognostic (1.69e-1)" "unprognostic (2.56e-1)" "unprognostic (9.89e-3)" "unprognostic (1.92e-1)" "unprognostic (4.00e-1)" "unprognostic (3.68e-2)" DUSP4 "HVH2, MKP-2, TYP" ENSG00000120875 "Dual specificity phosphatase 4" Q13115 8 29333064-29350684 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 30.4;stomach 1: 30.5" "Cell type enhanced" "Detected in many" "Breast lactating cells: 197.5;Endometrial glandular cells: 146.2;Endometrial luminal cells: 204.1;Foveolar cells: 126.6;Pancreatic acinar cells: 280.4;Parietal cells: 335.9;Prostatic club cells: 200.4;Retinal pigment epithelial cells: 136.4;T-cells: 141.7;Urothelial cells: 273.0" "Cell type enhanced" "Detected in many" "hippocampal CA4: 49.7" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 87.1" "Region enhanced" "Detected in all" "hippocampal formation: 47.4" "Immune cell enriched" "Detected in single" 9 "T-reg: 6.8" "Lineage enriched" "Detected in single" 20 "T-cells: 6.8" "Cancer enhanced" "Detected in all" "skin cancer: 149.2" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA077183 Supported Nucleoplasm NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 8: Pancreas - Proteolysis" "Cluster 29: Forebrain - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 9: T-cells - Adaptive immunity: Regulation" 26 Nucleoplasm "HPA077183: " "unprognostic (4.32e-1)" "unprognostic (1.84e-1)" "unprognostic (4.87e-2)" "potential prognostic unfavorable (5.25e-4)" "unprognostic (5.89e-2)" "unprognostic (2.20e-2)" "unprognostic (2.05e-2)" "unprognostic (1.77e-2)" "unprognostic (8.73e-3)" "unprognostic (6.22e-2)" "unprognostic (1.43e-2)" "potential prognostic favorable (2.51e-4)" "unprognostic (7.46e-3)" "unprognostic (1.05e-1)" "unprognostic (4.56e-2)" "unprognostic (2.76e-2)" "unprognostic (2.02e-1)" "unprognostic (9.94e-2)" "unprognostic (2.50e-2)" "unprognostic (6.81e-2)" "unprognostic (2.13e-1)" "unprognostic (2.07e-3)" "unprognostic (3.51e-1)" "unprognostic (3.15e-2)" "unprognostic (2.77e-1)" "unprognostic (1.98e-1)" "unprognostic (3.34e-2)" "unprognostic (1.00e-1)" "unprognostic (1.97e-1)" "unprognostic (1.79e-2)" "unprognostic (1.57e-3)" DUSP5 HVH3 ENSG00000138166 "Dual specificity phosphatase 5" Q16690 10 110497907-110511533 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "urinary bladder: 163.7" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 330.4;Esophageal apical cells: 652.9;Ocular epithelial cells: 568.8;pDCs: 404.3;Plasma cells: 430.6;Prostatic club cells: 306.5;Respiratory secretory cells: 238.0;Urothelial cells: 550.3" "Cell type enhanced" "Detected in many" "endothelial cell: 102.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 10.3;plasmacytoid DC: 14.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Region enhanced" "Detected in all" "cerebellum: 60.7" "Region enriched" "Detected in many" 5 "cerebellum: 61.2" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 15: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 78: Plasma cells - Antibody production & ER-stress response" 6 "unprognostic (5.16e-2)" "unprognostic (1.18e-2)" "unprognostic (1.69e-2)" "unprognostic (1.67e-1)" "unprognostic (2.86e-1)" "unprognostic (2.18e-1)" "unprognostic (2.72e-2)" "unprognostic (2.38e-1)" "unprognostic (1.77e-3)" "potential prognostic favorable (5.71e-5)" "unprognostic (1.17e-1)" "unprognostic (7.29e-3)" "unprognostic (1.16e-1)" "unprognostic (2.04e-2)" "unprognostic (4.66e-2)" "potential prognostic unfavorable (4.21e-5)" "unprognostic (1.44e-1)" "unprognostic (1.08e-2)" "unprognostic (1.50e-1)" "unprognostic (1.67e-2)" "unprognostic (9.57e-2)" "unprognostic (2.55e-2)" "unprognostic (4.19e-3)" "unprognostic (3.18e-3)" "unprognostic (5.92e-2)" "potential prognostic favorable (1.07e-5)" "unprognostic (1.81e-2)" "unprognostic (1.87e-1)" "unprognostic (4.44e-2)" "unprognostic (2.44e-1)" "unprognostic (6.57e-2)" DUSP6 "MKP-3, PYST1" ENSG00000139318 "Dual specificity phosphatase 6" Q16828 12 89347235-89352501 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 213.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 383.7;Kupffer cells: 200.9;Macrophages: 185.7;Mast cells: 284.5;Medullary thymic epithelial cells: 350.4;monocytes: 380.1;Neutrophil progenitors: 262.5;Retinal pigment epithelial cells: 392.2" "Cell type enhanced" "Detected in many" "endothelial cell: 65.1" "Cancer enhanced" "Detected in all" "Thyroid Carcinoma (TCGA): 289.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 1642.6" "Group enriched" "Detected in all" 13 "granulocytes: 1642.6;monocytes: 845.6" "Low cancer specificity" "Detected in all" "Adrenal gland - Endothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017566, HPA053188, HPA064692" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 23: Choroid plexus - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 14 "Nucleoplasm, Cytosol" "CAB017566: , HPA053188: , HPA064692: " "unprognostic (1.77e-2)" "unprognostic (2.29e-2)" "unprognostic (1.63e-1)" "unprognostic (2.92e-3)" "unprognostic (2.72e-1)" "unprognostic (2.80e-1)" "unprognostic (7.99e-3)" "unprognostic (1.16e-3)" "unprognostic (6.75e-3)" "unprognostic (1.03e-1)" "validated prognostic favorable (3.36e-7)" "validated prognostic favorable (1.50e-4)" "unprognostic (6.27e-3)" "unprognostic (2.92e-2)" "unprognostic (5.37e-3)" "unprognostic (1.70e-1)" "unprognostic (1.42e-1)" "unprognostic (3.17e-3)" "unprognostic (3.19e-1)" "unprognostic (1.41e-1)" "unprognostic (1.32e-1)" "unprognostic (3.29e-3)" "unprognostic (1.96e-2)" "unprognostic (1.77e-1)" "unprognostic (2.76e-1)" "unprognostic (1.81e-2)" "unprognostic (1.30e-1)" "unprognostic (5.17e-2)" "unprognostic (3.87e-2)" "unprognostic (1.25e-1)" "unprognostic (8.38e-3)" DUSP7 "MKP-X, PYST2" ENSG00000164086 "Dual specificity phosphatase 7" Q16829 3 52048919-52056571 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 84.9;Basal keratinocytes: 97.8;Esophageal apical cells: 48.0;Esophageal basal cells: 57.9;Esophageal suprabasal cells: 79.8;Megakaryocytes: 49.5;Ocular epithelial cells: 84.7;Suprabasal keratinocytes: 96.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073007 Approved NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 26: Keratinocytes - Keratinization" 9 "HPA073007: " "unprognostic (1.43e-1)" "unprognostic (2.37e-1)" "unprognostic (2.00e-2)" "unprognostic (1.44e-2)" "unprognostic (1.65e-1)" "unprognostic (2.49e-2)" "unprognostic (3.11e-1)" "potential prognostic favorable (1.78e-6)" "unprognostic (1.72e-2)" "unprognostic (1.49e-1)" "unprognostic (4.98e-3)" "unprognostic (5.91e-3)" "potential prognostic unfavorable (3.00e-5)" "unprognostic (1.58e-2)" "unprognostic (2.64e-2)" "unprognostic (1.39e-1)" "unprognostic (5.17e-3)" "unprognostic (1.04e-1)" "unprognostic (6.71e-2)" "unprognostic (1.28e-2)" "unprognostic (4.93e-2)" "unprognostic (3.49e-3)" "unprognostic (1.08e-3)" "potential prognostic unfavorable (8.81e-6)" "unprognostic (1.86e-2)" "unprognostic (3.09e-2)" "unprognostic (1.30e-1)" "unprognostic (1.35e-1)" "unprognostic (1.47e-1)" "unprognostic (3.10e-3)" "unprognostic (4.94e-2)" DUSP8 "C11orf81, FLJ42958, HB5, HVH-5" ENSG00000184545 "Dual specificity phosphatase 8" Q13202 11 1554051-1572271 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 44.4" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 22.1;Brain inhibitory neurons: 24.0;Distal convoluted tubule cells: 5.0;Oligodendrocyte progenitor cells: 8.4;Oligodendrocytes: 9.2;Other brain neurons: 20.3;Podocytes: 8.0;Renal collecting duct intercalated cells: 6.5;Renal collecting duct principal cells: 4.1;Renal connecting tubule cells: 7.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Smooth muscle cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020071 Approved Approved Cytosol NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 4 Cytosol "HPA020071: " "unprognostic (1.09e-1)" "unprognostic (1.70e-1)" "unprognostic (1.26e-2)" "unprognostic (9.18e-2)" "unprognostic (2.41e-1)" "unprognostic (1.70e-3)" "unprognostic (1.86e-1)" "unprognostic (2.19e-1)" "unprognostic (1.64e-1)" "unprognostic (1.72e-1)" "unprognostic (7.16e-3)" "unprognostic (2.53e-1)" DUSP9 "MKP-4, MKP4" ENSG00000130829 "Dual specificity phosphatase 9" Q99956 X 153642492-153651326 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "kidney: 52.1;placenta: 68.3" "Group enriched" "Detected in some" 30 "Cytotrophoblasts: 1517.6;Migrating cytotrophoblasts: 545.5;Syncytiotrophoblasts: 1984.4" "Cell type enhanced" "Detected in many" "hippocampal dentate gyrus: 11.1" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 15.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Gastric cancer: 21.2;liver cancer: 62.7" "Kidney - Ascending Loop of Henle cells, Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA003336 Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 51: Neurons - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 19 "Endoplasmic reticulum" "HPA003336: " "unprognostic (7.31e-2)" "unprognostic (7.66e-2)" "unprognostic (2.43e-2)" "unprognostic (7.00e-2)" "unprognostic (9.46e-2)" "unprognostic (3.57e-3)" "unprognostic (5.97e-2)" "unprognostic (1.29e-2)" "unprognostic (1.50e-2)" "unprognostic (1.13e-2)" "unprognostic (2.75e-3)" "unprognostic (2.27e-2)" "unprognostic (5.27e-2)" "potential prognostic favorable (8.44e-4)" "unprognostic (2.60e-1)" "unprognostic (8.30e-2)" "unprognostic (1.12e-1)" "unprognostic (8.41e-2)" "unprognostic (1.94e-1)" "unprognostic (3.86e-3)" DUT dUTPase ENSG00000128951 "Deoxyuridine triphosphatase" P33316 15 48331011-48343373 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early primary spermatocytes: 616.9;Erythrocyte progenitors: 735.6;Megakaryocyte progenitors: 588.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054422, HPA060360" Enhanced Supported Nucleoplasm No Yes 15000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 54: Non-specific - Ribosome" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 27: Non-specific - Cell proliferation" 4 Nucleoplasm "HPA054422: , HPA060360: " "unprognostic (3.72e-2)" "unprognostic (1.27e-2)" "unprognostic (1.81e-1)" "unprognostic (3.80e-2)" "unprognostic (5.26e-3)" "unprognostic (8.32e-2)" "unprognostic (1.16e-2)" "unprognostic (7.62e-2)" "unprognostic (1.77e-1)" "unprognostic (3.35e-3)" "potential prognostic favorable (3.82e-4)" "unprognostic (4.76e-2)" "unprognostic (5.97e-2)" "unprognostic (1.62e-1)" "unprognostic (5.13e-2)" "potential prognostic unfavorable (7.15e-4)" "unprognostic (5.88e-2)" "unprognostic (9.07e-3)" "unprognostic (6.44e-2)" "unprognostic (7.68e-2)" "unprognostic (1.91e-1)" "unprognostic (3.00e-2)" "unprognostic (5.76e-2)" "unprognostic (1.20e-1)" "unprognostic (1.02e-2)" "unprognostic (2.96e-2)" "unprognostic (6.89e-3)" "unprognostic (6.30e-2)" "unprognostic (1.38e-1)" "unprognostic (1.97e-3)" "unprognostic (3.24e-2)" DUX4 ENSG00000260596 "Double homeobox 4" Q9UBX2 4 190173774-190185942 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Transcription factors, Transporters" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Early spermatids: 2.7;Late spermatids: 2.6" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Breast Invasive Carcinoma (TCGA): 1.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "Myeloma: 10.2" "Low region specificity" "Detected in some" HPA058451 Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Cytosol" NA NA "Cluster 53: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 45 "Nucleoplasm, Nucleoli" "Golgi apparatus, Cytosol" "HPA058451: " "unprognostic (9.44e-3)" "unprognostic (1.41e-1)" DUXA ENSG00000258873 "Double homeobox A" A6NLW8 19 57154021-57167485 "Essential proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Late spermatids: 1.6;Sertoli cells: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA059358 Uncertain NA NA "Cluster 9: Non-specific - Receptor signaling" "Cluster 56: Non-specific - Sensory perception" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" "HPA059358: " DUXB ENSG00000282757 "Double homeobox B" A0A1W2PPF3 16 75693893-75701461 "Predicted intracellular proteins" DNA-binding "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Adipocytes: 5.1;Cardiomyocytes: 8.7;Cone photoreceptor cells: 6.2;Epicardial cells: 9.1;Fibro-adipogenic progenitors: 7.6;Mesothelial cells: 3.3;Myonuclei: 5.6;Myosatellite cells: 4.2;Oocytes: 9.2;Retinal ganglion cells: 3.9;Retinal horizontal cells: 4.0;Rod photoreceptor cells: 3.4" "Low cell type specificity" "Detected in some" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" NA NA "Cluster 30: White matter - Myelination" "Cluster 47: Leukemia - Hemostasis" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" DVL1 ENSG00000107404 "Dishevelled segment polarity protein 1" O14640 1 1335276-1349418 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Wnt signaling pathway" "Developmental protein" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 215.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 77.6;Esophageal apical cells: 91.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011538, HPA073607" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Focal adhesion sites" NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 51: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 30 "Nucleoplasm, Plasma membrane" "Vesicles, Focal adhesion sites" "CAB011538: , HPA073607: " "unprognostic (8.54e-2)" "unprognostic (8.92e-2)" "unprognostic (3.67e-1)" "unprognostic (1.90e-2)" "unprognostic (1.93e-1)" "unprognostic (6.58e-2)" "unprognostic (1.35e-1)" "unprognostic (1.46e-2)" "unprognostic (4.56e-2)" "unprognostic (1.63e-1)" "unprognostic (2.65e-2)" "unprognostic (2.62e-1)" "unprognostic (1.27e-1)" "unprognostic (1.05e-3)" "unprognostic (2.67e-2)" "unprognostic (1.31e-1)" "unprognostic (1.15e-2)" "unprognostic (4.05e-3)" "unprognostic (2.73e-1)" "unprognostic (4.20e-2)" "unprognostic (4.67e-2)" "potential prognostic unfavorable (4.63e-4)" "unprognostic (4.04e-2)" "unprognostic (3.17e-2)" "unprognostic (6.12e-2)" "unprognostic (7.70e-3)" "unprognostic (5.40e-2)" "unprognostic (1.15e-1)" "unprognostic (1.85e-2)" "unprognostic (1.97e-1)" "unprognostic (1.49e-1)" DVL2 ENSG00000004975 "Dishevelled segment polarity protein 2" O14641 17 7225342-7234517 "Predicted intracellular proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021611, HPA022914, HPA064732" Approved Approved "Nucleoplasm,Nuclear bodies,Aggresome" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 64: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 42: Non-specific - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 146 "Nucleoplasm, Nuclear bodies" Aggresome "HPA021611: , HPA022914: , HPA064732: " "unprognostic (1.35e-1)" "unprognostic (8.22e-2)" "unprognostic (6.12e-2)" "unprognostic (1.75e-1)" "unprognostic (9.77e-2)" "unprognostic (3.70e-1)" "unprognostic (2.07e-1)" "unprognostic (7.57e-3)" "unprognostic (2.99e-2)" "unprognostic (2.90e-3)" "potential prognostic favorable (4.62e-4)" "unprognostic (5.01e-3)" "unprognostic (1.44e-1)" "potential prognostic unfavorable (9.64e-6)" "unprognostic (2.47e-2)" "unprognostic (4.50e-3)" "unprognostic (1.40e-1)" "unprognostic (3.32e-1)" "unprognostic (6.28e-2)" "unprognostic (1.92e-1)" "unprognostic (4.04e-1)" "unprognostic (8.55e-3)" "unprognostic (8.16e-3)" "unprognostic (2.01e-1)" "unprognostic (2.25e-1)" "unprognostic (8.28e-2)" "unprognostic (2.38e-1)" "unprognostic (3.32e-1)" "unprognostic (3.21e-1)" "unprognostic (3.43e-2)" "unprognostic (3.63e-1)" DVL3 KIAA0208 ENSG00000161202 "Dishevelled segment polarity protein 3" Q92997 3 184155377-184173614 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Wnt signaling pathway" "Developmental protein" "Cancer-related genes, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046486, HPA058265" Approved Approved "Golgi apparatus,Plasma membrane,Intermediate filaments,Midbody ring,Centrosome,Basal body" Yes No "Cluster 7: Non-specific - Innate immune response" "Cluster 74: Non-specific - Signal transduction" "Cluster 55: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 152 "Midbody ring, Basal body" "Golgi apparatus, Plasma membrane, Intermediate filaments, Centrosome" "CAB046486: , HPA058265: " "unprognostic (2.01e-1)" "unprognostic (2.20e-2)" "unprognostic (4.18e-1)" "unprognostic (6.29e-2)" "unprognostic (6.64e-3)" "unprognostic (1.41e-1)" "unprognostic (2.68e-2)" "unprognostic (5.97e-2)" "unprognostic (3.54e-1)" "unprognostic (2.91e-2)" "unprognostic (2.79e-3)" "unprognostic (8.30e-3)" "unprognostic (2.57e-2)" "unprognostic (1.14e-3)" "unprognostic (3.16e-2)" "unprognostic (2.33e-2)" "unprognostic (1.73e-2)" "unprognostic (3.80e-2)" "potential prognostic favorable (1.41e-4)" "unprognostic (4.48e-1)" "unprognostic (3.25e-2)" "unprognostic (7.03e-2)" "unprognostic (4.84e-2)" "potential prognostic unfavorable (7.04e-5)" "unprognostic (2.00e-2)" "unprognostic (1.23e-1)" "unprognostic (7.46e-2)" "unprognostic (1.83e-1)" "unprognostic (4.87e-1)" "unprognostic (7.61e-2)" "unprognostic (1.93e-1)" DXO DOM3Z ENSG00000204348 "Decapping exoribonuclease" O77932 6 31969810-31972290 "Predicted intracellular proteins" "Exonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 11 "Early spermatids: 502.4;Late primary spermatocytes: 176.7;Late spermatids: 342.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046708 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 18: Non-specific - Translation" "Cluster 21: Testis - Mixed function" "Cluster 44: Non-specific - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 15 "Nucleoplasm, Cytosol" "Plasma membrane" "HPA046708: " "unprognostic (3.73e-2)" "unprognostic (1.56e-1)" "unprognostic (5.80e-2)" "unprognostic (5.19e-2)" "unprognostic (2.81e-1)" "unprognostic (2.19e-1)" "unprognostic (2.11e-2)" "unprognostic (5.21e-3)" "potential prognostic unfavorable (6.12e-4)" "unprognostic (2.76e-3)" "unprognostic (1.95e-1)" "unprognostic (6.37e-2)" "potential prognostic unfavorable (4.90e-4)" "unprognostic (6.03e-2)" "unprognostic (1.30e-1)" "unprognostic (1.45e-2)" "unprognostic (1.93e-1)" "unprognostic (2.37e-3)" "unprognostic (2.33e-2)" "unprognostic (6.94e-3)" "unprognostic (8.73e-2)" "unprognostic (3.06e-1)" "unprognostic (1.86e-2)" "unprognostic (8.19e-2)" "unprognostic (4.75e-2)" "unprognostic (7.97e-3)" "unprognostic (1.40e-1)" "unprognostic (1.11e-1)" "unprognostic (4.34e-2)" DYDC1 "bA36D19.5, DPY30D1" ENSG00000170788 "DPY30 domain containing 1" Q8WWB3 10 80336105-80356755 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "testis: 114.4" "Cell type enriched" "Detected in some" 4 "Late primary spermatocytes: 809.0" "Cell type enriched" "Detected in some" 4 "ependymal cell: 43.1" "Cancer enhanced" "Detected in single" "Uterine Corpus Endometrial Carcinoma (TCGA): 3.2" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 6 "basophil: 1.7" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.7" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA037790, HPA037791" Uncertain Approved "Mid piece,Principal piece,End piece" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 17: Choroid plexus - Cilium" "Cluster 59: Leukemia - T-cell receptor" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 26 "Mid piece, Principal piece, End piece" "HPA037790: , HPA037791: " "unprognostic (3.78e-2)" "unprognostic (1.95e-1)" DYDC2 "bA36D19.6, MGC16186" ENSG00000133665 "DPY30 domain containing 2" Q96IM9 10 80344745-80368073 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "choroid plexus: 25.3;fallopian tube: 91.5" "Cell type enhanced" "Detected in some" "Early spermatids: 51.4;Endometrial ciliated cells: 218.3;Ependymal cells: 82.8;Epididymal efferent duct ciliated cells: 183.8;Fallopian tube ciliated cells: 296.1;Late primary spermatocytes: 81.9;Late spermatids: 49.6;Respiratory ciliated cells: 261.3" "Cell type enriched" "Detected in many" 10 "ependymal cell: 132.9" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 13.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA038006, HPA038007" Enhanced Approved "Vesicles,Cytosol,Principal piece" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" 9 "Vesicles, Principal piece" Cytosol "HPA038006: , HPA038007: " "unprognostic (7.08e-2)" "unprognostic (2.25e-1)" "unprognostic (1.05e-2)" "potential prognostic favorable (1.74e-4)" "unprognostic (2.66e-1)" "unprognostic (2.57e-1)" "unprognostic (3.45e-1)" "unprognostic (2.60e-2)" "unprognostic (3.34e-1)" "unprognostic (1.61e-1)" "unprognostic (1.41e-1)" "unprognostic (1.52e-2)" "unprognostic (6.80e-2)" "unprognostic (3.20e-3)" "unprognostic (1.15e-2)" "unprognostic (3.02e-2)" "unprognostic (9.28e-2)" DYM "DMC, FLJ20071, SMC" ENSG00000141627 Dymeclin Q7RTS9 18 49036387-49461347 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043551, HPA049187" Approved Supported "Golgi apparatus" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 8: Pancreas - Proteolysis" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 25: Non-specific - Ribosome" "Cluster 7: Non-specific - Transcription" 20 "Golgi apparatus" "HPA043551: , HPA049187: " "unprognostic (9.67e-2)" "unprognostic (2.03e-2)" "unprognostic (2.05e-1)" "unprognostic (2.89e-1)" "unprognostic (3.18e-3)" "unprognostic (1.66e-1)" "unprognostic (1.01e-1)" "unprognostic (6.88e-3)" "unprognostic (3.79e-1)" "potential prognostic unfavorable (2.52e-4)" "validated prognostic favorable (6.25e-6)" "validated prognostic favorable (3.11e-4)" "unprognostic (7.06e-2)" "unprognostic (1.29e-2)" "potential prognostic unfavorable (3.46e-4)" "unprognostic (2.39e-1)" "unprognostic (1.44e-1)" "unprognostic (3.91e-1)" "unprognostic (1.86e-1)" "unprognostic (1.79e-1)" "unprognostic (3.21e-2)" "potential prognostic unfavorable (7.62e-4)" "unprognostic (7.58e-2)" "unprognostic (9.02e-2)" "unprognostic (2.06e-1)" "unprognostic (5.92e-2)" "unprognostic (2.39e-2)" "unprognostic (7.75e-2)" "unprognostic (1.96e-1)" "unprognostic (1.78e-2)" "unprognostic (8.23e-2)" DYNAP "C18orf26, FLJ39106" ENSG00000178690 "Dynactin associated protein" Q8N1N2 18 54587757-54599493 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "esophagus: 27.6" "Group enriched" "Detected in some" 18 "Esophageal apical cells: 341.2;Esophageal suprabasal cells: 101.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Skin - Outer root sheath cells" "Not detected" "Not detected" HPA011148 Uncertain NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 9: Non-specific - Receptor signaling" "Cluster 56: Non-specific - Sensory perception" "Cluster 85: Squamous epithelial cells - Keratinization" "HPA011148: " "unprognostic (2.15e-1)" "unprognostic (1.61e-3)" "unprognostic (1.68e-1)" "unprognostic (9.73e-2)" "unprognostic (1.03e-1)" "unprognostic (1.62e-1)" "unprognostic (2.02e-1)" "unprognostic (2.95e-1)" "unprognostic (4.85e-2)" DYNC1H1 "CMT2O, DHC1, DNCH1, Dnchc1, DNCL, DNECL, HL-3, p22" ENSG00000197102 "Dynein cytoplasmic 1 heavy chain 1" Q14204 14 101964573-102056443 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Transport" "Motor protein" "Charcot-Marie-Tooth disease, Disease variant, Intellectual disability, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 15.0" "Cell type enhanced" "Detected in all" "Retinal ganglion cells: 591.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003742, CAB010443" Enhanced Approved "Centrosome,Cytosol,Flagellar centriole,Mid piece,Annulus" NA NA 540000 "Cluster 21: Neutrophils - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 149 Cytosol "Centrosome, Flagellar centriole, Mid piece, Annulus" "CAB010443: , HPA003742: " "unprognostic (5.32e-2)" "unprognostic (2.66e-1)" "unprognostic (1.28e-1)" "unprognostic (1.72e-2)" "unprognostic (7.30e-2)" "unprognostic (9.32e-2)" "unprognostic (4.14e-2)" "unprognostic (1.09e-1)" "unprognostic (1.01e-2)" "unprognostic (4.75e-2)" "unprognostic (7.63e-2)" "unprognostic (1.92e-1)" "unprognostic (2.22e-1)" "unprognostic (4.18e-2)" "unprognostic (1.97e-2)" "unprognostic (5.05e-2)" "unprognostic (2.98e-1)" "unprognostic (6.14e-3)" "unprognostic (3.77e-2)" "unprognostic (3.41e-1)" "unprognostic (4.56e-2)" "unprognostic (1.17e-2)" "unprognostic (1.37e-1)" "unprognostic (6.41e-2)" "unprognostic (5.82e-2)" "unprognostic (2.65e-3)" "unprognostic (5.66e-3)" "unprognostic (3.00e-1)" "unprognostic (1.75e-1)" "unprognostic (3.30e-2)" "unprognostic (2.23e-1)" DYNC1I1 "DNCI1, DNCIC1" ENSG00000158560 "Dynein cytoplasmic 1 intermediate chain 1" O14576 7 95772506-96110322 "Predicted intracellular proteins" Transport "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 61.4" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 702.0;Brain excitatory neurons: 633.1;Brain inhibitory neurons: 579.0;Choroid plexus epithelial cells: 862.8;Corticotrophs: 861.3;Gonadotrophs: 522.8;Lactotrophs: 653.6;Müller glia: 705.2;Other brain neurons: 573.7;Podocytes: 687.1;Retinal ganglion cells: 475.1;Retinal pigment epithelial cells: 588.3;Somatotrophs: 606.7;Thyrotrophs: 429.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal medulla cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061689 Enhanced Supported NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 27: Cerebellum - Synaptic function" "Cluster 1: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 26 "HPA061689: " "unprognostic (1.51e-1)" "unprognostic (1.35e-1)" "unprognostic (1.84e-1)" "unprognostic (3.16e-2)" "unprognostic (1.62e-2)" "unprognostic (2.86e-2)" "unprognostic (9.78e-2)" "unprognostic (1.21e-2)" "potential prognostic unfavorable (4.88e-4)" "unprognostic (2.03e-2)" "unprognostic (3.68e-3)" "unprognostic (4.64e-2)" "unprognostic (1.05e-1)" "unprognostic (1.74e-3)" "unprognostic (3.94e-1)" "unprognostic (3.39e-1)" "unprognostic (1.23e-1)" "unprognostic (3.82e-2)" "unprognostic (3.01e-1)" "unprognostic (7.24e-3)" "unprognostic (2.90e-1)" "unprognostic (8.12e-2)" "unprognostic (4.42e-1)" "unprognostic (9.87e-3)" "unprognostic (2.57e-2)" "potential prognostic unfavorable (7.46e-5)" "unprognostic (1.87e-1)" "unprognostic (3.32e-3)" "unprognostic (1.56e-2)" DYNC1I2 "DIC74, DNCI2" ENSG00000077380 "Dynein cytoplasmic 1 intermediate chain 2" Q13409 2 171687409-171750158 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction, Transport" "Motor protein" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033836, HPA040619, HPA053987" Supported Approved "Microtubules,Centrosome,Cytosol,Flagellar centriole,Mid piece,Principal piece,End piece" NA NA 57000 "Cluster 32: Basophils - Transcription" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 17: Non-specific - RNA processing" 77 "Microtubules, Centrosome, Cytosol, Flagellar centriole, Mid piece, Principal piece" "End piece" "CAB033836: , HPA040619: , HPA053987: " "unprognostic (4.58e-2)" "unprognostic (6.13e-3)" "unprognostic (7.79e-2)" "unprognostic (1.29e-1)" "unprognostic (3.47e-1)" "unprognostic (2.71e-1)" "unprognostic (8.39e-2)" "unprognostic (9.59e-2)" "unprognostic (6.01e-2)" "unprognostic (2.49e-1)" "validated prognostic favorable (1.92e-8)" "validated prognostic favorable (5.76e-5)" "unprognostic (6.81e-2)" "unprognostic (1.26e-2)" "unprognostic (2.06e-2)" "unprognostic (8.71e-3)" "unprognostic (1.84e-2)" "unprognostic (7.28e-3)" "unprognostic (5.25e-2)" "unprognostic (3.50e-1)" "unprognostic (1.07e-2)" "unprognostic (1.38e-3)" "potential prognostic unfavorable (5.45e-4)" "unprognostic (1.62e-1)" "unprognostic (9.29e-2)" "unprognostic (1.93e-1)" "unprognostic (2.26e-1)" "unprognostic (1.19e-1)" "unprognostic (2.51e-1)" "unprognostic (5.85e-2)" "unprognostic (1.85e-1)" DYNC1LI1 DNCLI1 ENSG00000144635 "Dynein cytoplasmic 1 light intermediate chain 1" Q9Y6G9 3 32525974-32570858 "Predicted intracellular proteins" "Cell cycle, Cell division, Host-virus interaction, Mitosis, Transport" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 238.7;Neutrophils: 248.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035013 Approved Uncertain "Nucleoplasm,Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 40: Non-specific - Mixed function" "Cluster 16: Non-specific - Transcription" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 82: Dendritic cells - Antigen presentation" 91 Centrosome "Nucleoplasm, Plasma membrane, Cytosol" "HPA035013: " "unprognostic (2.07e-1)" "unprognostic (3.17e-1)" "unprognostic (6.20e-2)" "unprognostic (1.47e-1)" "unprognostic (2.50e-1)" "unprognostic (2.36e-1)" "unprognostic (5.15e-2)" "unprognostic (3.39e-3)" "unprognostic (3.98e-2)" "potential prognostic unfavorable (6.95e-5)" "potential prognostic favorable (1.12e-8)" "unprognostic (6.65e-2)" "unprognostic (1.92e-1)" "validated prognostic unfavorable (1.41e-7)" "validated prognostic unfavorable (8.83e-4)" "unprognostic (6.86e-2)" "unprognostic (1.44e-2)" "unprognostic (5.16e-2)" "unprognostic (2.15e-1)" "unprognostic (3.25e-2)" "unprognostic (7.26e-3)" "unprognostic (1.84e-1)" "unprognostic (2.50e-2)" "unprognostic (5.76e-2)" "unprognostic (3.30e-2)" "unprognostic (6.51e-2)" "unprognostic (9.03e-2)" "unprognostic (3.08e-2)" "unprognostic (9.07e-3)" "unprognostic (3.24e-1)" "unprognostic (2.01e-1)" DYNC1LI2 DNCLI2 ENSG00000135720 "Dynein cytoplasmic 1 light intermediate chain 2" O43237 16 66720893-66751609 "Predicted intracellular proteins" Transport "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 269.4" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049538, HPA057201" Approved Approved "Centrosome,Cytosol,End piece" NA NA 19000 "Cluster 28: Neutrophils - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 17: Non-specific - RNA processing" 34 "Centrosome, End piece" Cytosol "HPA049538: , HPA057201: " "unprognostic (6.60e-2)" "unprognostic (5.63e-2)" "unprognostic (3.48e-1)" "unprognostic (7.75e-2)" "unprognostic (5.13e-1)" "unprognostic (2.75e-2)" "unprognostic (4.37e-2)" "unprognostic (7.76e-2)" "unprognostic (1.12e-1)" "unprognostic (1.46e-2)" "validated prognostic favorable (5.39e-5)" "validated prognostic favorable (7.96e-4)" "unprognostic (2.29e-1)" "unprognostic (6.02e-3)" "unprognostic (6.49e-2)" "unprognostic (4.13e-2)" "unprognostic (7.18e-2)" "unprognostic (4.71e-3)" "unprognostic (8.11e-2)" "unprognostic (1.23e-1)" "unprognostic (2.06e-3)" "unprognostic (2.20e-2)" "unprognostic (4.14e-3)" "unprognostic (2.40e-2)" "unprognostic (3.13e-2)" "unprognostic (1.78e-1)" "unprognostic (2.09e-1)" "unprognostic (1.60e-2)" "unprognostic (1.93e-1)" "unprognostic (1.59e-2)" "unprognostic (5.70e-2)" DYNC2H1 "DHC1b, DHC2, DNCH2, DYH1B, hdhc11" ENSG00000187240 "Dynein cytoplasmic 2 heavy chain 1" Q8NCM8 11 103109410-103479863 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Developmental protein, Motor protein" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 18.0" "Cell type enhanced" "Detected in all" "Corticotrophs: 481.2;Distal convoluted tubule cells: 495.3;Endometrial ciliated cells: 568.1;Ependymal cells: 1088.9;Fallopian tube ciliated cells: 539.2;Respiratory ciliated cells: 952.2;Somatotrophs: 435.2;Thyrotrophs: 431.0" "Cell type enhanced" "Detected in all" "ependymal cell: 1183.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Lung - Respiratory ciliated cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039015, HPA039016" Approved Approved "Nucleoplasm,Mitochondria,Cytosol,Mid piece,Principal piece" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 3: Rhabdoid - Membrane components" "Cluster 34: Ciliated cells - Cilia assembly & function" 7 "Mitochondria, Mid piece" "Nucleoplasm, Cytosol, Principal piece" "HPA039015: , HPA039016: " "unprognostic (1.13e-2)" "unprognostic (3.02e-1)" "unprognostic (9.08e-2)" "unprognostic (1.37e-2)" "unprognostic (3.76e-2)" "unprognostic (3.43e-1)" "unprognostic (2.75e-1)" "unprognostic (9.25e-3)" "unprognostic (1.29e-2)" "validated prognostic favorable (5.10e-11)" "validated prognostic favorable (1.27e-4)" "unprognostic (5.29e-2)" "unprognostic (2.78e-2)" "unprognostic (3.12e-2)" "unprognostic (1.13e-1)" "unprognostic (2.43e-1)" "unprognostic (3.04e-2)" "unprognostic (1.12e-1)" "unprognostic (8.18e-2)" "unprognostic (2.93e-1)" "unprognostic (1.64e-3)" "unprognostic (9.46e-2)" "unprognostic (1.96e-1)" "unprognostic (1.92e-1)" "unprognostic (1.37e-1)" DYNC2I1 "CFAP163, DIC6, FAP163, FLJ10300, WDR60" ENSG00000126870 "Dynein 2 intermediate chain 1" Q8WVS4 7 158856558-158956747 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 575.7;Endometrial ciliated cells: 489.5;Ependymal cells: 695.7;Late primary spermatocytes: 888.4;Respiratory ciliated cells: 501.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Spleen - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020607, HPA021316" Approved Supported "Primary cilium,Centrosome,Basal body,Cytosol" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 39: Non-specific - Transcription" "Cluster 34: Ciliated cells - Cilia assembly & function" 28 "Centrosome, Basal body" "Primary cilium, Cytosol" "HPA020607: , HPA021316: " "unprognostic (3.79e-2)" "unprognostic (4.51e-1)" "unprognostic (1.31e-1)" "unprognostic (3.33e-1)" "unprognostic (3.77e-1)" "unprognostic (2.55e-1)" "unprognostic (2.30e-1)" "unprognostic (5.86e-2)" "unprognostic (6.07e-3)" "potential prognostic favorable (5.24e-4)" "unprognostic (1.16e-1)" "unprognostic (4.76e-3)" "unprognostic (1.88e-1)" "unprognostic (1.77e-1)" "unprognostic (1.07e-3)" "unprognostic (5.09e-1)" "unprognostic (1.46e-1)" "unprognostic (7.05e-2)" "unprognostic (2.90e-1)" "unprognostic (1.50e-1)" "unprognostic (2.69e-3)" "unprognostic (3.29e-1)" "unprognostic (1.48e-1)" "unprognostic (3.14e-1)" "unprognostic (9.70e-2)" "unprognostic (1.95e-1)" "unprognostic (6.64e-2)" "unprognostic (2.22e-3)" "unprognostic (6.78e-2)" DYNC2I2 "bA216B9.3, CFAP133, DIC5, FAP133, MGC20486, WDR34" ENSG00000119333 "Dynein 2 intermediate chain 2" Q96EX3 9 128633653-128656847 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 165.9;Enterocytes: 154.5;Fallopian tube ciliated cells: 155.7;Late primary spermatocytes: 156.4;Late spermatids: 367.9;Oocytes: 165.8;Respiratory ciliated cells: 195.9" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 37.9;ependymal cell: 40.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 35.9;naive B-cell: 53.2" "Lineage enriched" "Detected in all" 5 "B-cells: 53.2" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Kidney - Fibroblasts, Minor Salivary Gland - Minor salivary glandular cells, Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040764, HPA041091" Approved Supported "Nucleoplasm,Nucleoli,Nuclear bodies,Primary cilium,Centrosome,Basal body,Cytosol" NA Yes "Cluster 17: B-cells - Immunoglobulins" "Cluster 70: Non-specific - Protein processing" "Cluster 3: Choroid plexus - Cilium" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 35 "Nucleoplasm, Centrosome, Basal body" "Nucleoli, Nuclear bodies, Primary cilium, Cytosol" "HPA040764: , HPA041091: " "unprognostic (1.59e-1)" "unprognostic (4.79e-3)" "unprognostic (6.90e-3)" "unprognostic (2.40e-1)" "unprognostic (9.47e-2)" "unprognostic (2.66e-1)" "unprognostic (2.09e-1)" "unprognostic (2.12e-3)" "unprognostic (1.07e-1)" "potential prognostic favorable (8.09e-5)" "unprognostic (4.07e-2)" "potential prognostic favorable (8.31e-5)" "potential prognostic unfavorable (4.97e-4)" "unprognostic (2.60e-3)" "unprognostic (4.11e-2)" "unprognostic (4.29e-2)" "unprognostic (4.87e-2)" "unprognostic (1.01e-1)" "potential prognostic favorable (5.23e-4)" "unprognostic (1.70e-1)" "unprognostic (1.49e-1)" "unprognostic (8.67e-2)" "unprognostic (1.31e-1)" "unprognostic (1.46e-2)" "unprognostic (3.47e-1)" "unprognostic (4.57e-2)" "unprognostic (4.31e-1)" "unprognostic (3.89e-2)" "unprognostic (2.30e-3)" DYNC2LI1 "CGI-60, D2LIC, DKFZP564A033, LIC3" ENSG00000138036 "Dynein cytoplasmic 2 light intermediate chain 1" Q8TCX1 2 43774039-43810010 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Developmental protein, Motor protein" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ependymal cells: 202.5;Late primary spermatocytes: 330.9;Respiratory ciliated cells: 225.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Renal Papillary Cell Carcinoma (TCGA): 92.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 15.2" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062905 Approved Supported "Primary cilium,Basal body,Cytosol,Equatorial segment,Perinuclear theca,Mid piece,Principal piece,Annulus" NA NA "Cluster 32: Basophils - Transcription" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 15: Kidney cancer - Membrane components" "Cluster 34: Ciliated cells - Cilia assembly & function" 15 "Cytosol, Mid piece" "Primary cilium, Basal body, Equatorial segment, Perinuclear theca, Principal piece, Annulus" "HPA062905: " "unprognostic (3.85e-1)" "unprognostic (1.31e-1)" "unprognostic (3.84e-1)" "unprognostic (6.16e-2)" "unprognostic (1.84e-1)" "unprognostic (1.54e-2)" "unprognostic (3.32e-2)" "unprognostic (2.47e-2)" "unprognostic (3.57e-2)" "unprognostic (1.70e-1)" "potential prognostic favorable (1.52e-7)" "unprognostic (1.33e-2)" "potential prognostic favorable (4.48e-4)" "potential prognostic unfavorable (2.86e-4)" "unprognostic (4.31e-3)" "unprognostic (7.98e-2)" "unprognostic (5.66e-2)" "unprognostic (3.60e-1)" "unprognostic (4.39e-1)" "unprognostic (4.60e-1)" "unprognostic (1.59e-2)" "unprognostic (2.14e-2)" "unprognostic (3.08e-2)" "unprognostic (2.40e-1)" "potential prognostic favorable (2.45e-4)" "unprognostic (3.65e-1)" "unprognostic (5.31e-2)" "unprognostic (1.94e-1)" "unprognostic (2.54e-1)" "unprognostic (5.18e-2)" "unprognostic (9.00e-2)" DYNLL1 "DLC1, DLC8, DNCL1, hdlc1, LC8, PIN" ENSG00000088986 "Dynein light chain LC8-type 1" P63167 12 120469850-120498493 "Cancer-related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, DNA damage, Host-virus interaction, Transcription, Transcription regulation, Transport" "Activator, Motor protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 9920.4;Esophageal suprabasal cells: 5019.2;Fallopian tube ciliated cells: 2436.9;Late spermatids: 6544.0;Respiratory ciliated cells: 2307.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039954 Approved "Nucleoplasm,Cytosol,Mid piece,Principal piece" NA Yes 910000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 14: Neurons - Synaptic function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 85: Squamous epithelial cells - Keratinization" 430 "Nucleoplasm, Cytosol, Mid piece, Principal piece" "HPA039954: " "unprognostic (1.64e-2)" "unprognostic (1.12e-2)" "unprognostic (1.70e-1)" "unprognostic (2.32e-1)" "unprognostic (1.48e-1)" "unprognostic (3.60e-1)" "unprognostic (1.68e-2)" "unprognostic (1.60e-2)" "unprognostic (3.47e-2)" "potential prognostic unfavorable (5.36e-5)" "unprognostic (7.26e-2)" "unprognostic (3.56e-3)" "unprognostic (4.61e-3)" "potential prognostic unfavorable (9.70e-8)" "unprognostic (9.58e-2)" "potential prognostic unfavorable (1.16e-5)" "unprognostic (1.88e-2)" "unprognostic (9.73e-3)" "unprognostic (2.88e-1)" "unprognostic (7.41e-2)" "unprognostic (2.19e-2)" "unprognostic (1.13e-1)" "potential prognostic unfavorable (5.55e-5)" "unprognostic (9.94e-2)" "unprognostic (2.63e-1)" "potential prognostic unfavorable (1.98e-4)" "unprognostic (1.52e-3)" "unprognostic (5.19e-2)" "unprognostic (1.09e-1)" "unprognostic (3.90e-2)" "unprognostic (6.91e-2)" DYNLL2 "Dlc2, DNCL1B, MGC17810, RSPH22" ENSG00000264364 "Dynein light chain LC8-type 2" Q96FJ2 17 58083419-58095542 "Predicted intracellular proteins" Transport "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 523.2;Late spermatids: 1191.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039954 Uncertain "Nucleoplasm,Cytosol,Mid piece,Principal piece" NA NA 760000 "Cluster 52: Non-specific - Cellular respiration" "Cluster 45: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 338 "Nucleoplasm, Cytosol, Mid piece, Principal piece" "HPA039954: " "unprognostic (1.02e-2)" "unprognostic (1.13e-2)" "unprognostic (3.11e-1)" "unprognostic (3.47e-2)" "unprognostic (6.21e-2)" "unprognostic (9.30e-2)" "unprognostic (4.30e-1)" "unprognostic (1.65e-1)" "unprognostic (4.26e-2)" "unprognostic (2.60e-2)" "validated prognostic favorable (5.92e-10)" "validated prognostic favorable (2.72e-6)" "potential prognostic favorable (1.44e-6)" "unprognostic (1.27e-3)" "unprognostic (6.54e-2)" "unprognostic (1.43e-1)" "unprognostic (2.68e-1)" "unprognostic (1.38e-1)" "unprognostic (7.38e-3)" "unprognostic (1.10e-1)" "unprognostic (4.13e-1)" "potential prognostic favorable (9.53e-4)" "unprognostic (3.37e-1)" "unprognostic (1.82e-1)" "unprognostic (2.37e-1)" "unprognostic (8.89e-2)" "unprognostic (2.25e-1)" "unprognostic (2.12e-1)" "unprognostic (2.91e-1)" "unprognostic (1.74e-1)" "unprognostic (2.91e-2)" DYNLRB1 "DNCL2A, DNLC2A, ROBLD1" ENSG00000125971 "Dynein light chain roadblock-type 1" Q9NP97 20 34516395-34540958 "Essential proteins, Plasma proteins, Predicted intracellular proteins" Transport "Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 222.2;Epididymal clear cells: 159.2;Goblet cells: 170.7;Megakaryocytes: 204.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB009845 Approved NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 15: Non-specific - Protein processing" 42 "CAB009845: " "unprognostic (1.60e-1)" "unprognostic (8.77e-2)" "unprognostic (1.32e-1)" "unprognostic (1.35e-1)" "unprognostic (3.77e-2)" "unprognostic (1.21e-1)" "unprognostic (1.22e-1)" "unprognostic (1.87e-1)" "unprognostic (1.29e-1)" "unprognostic (2.22e-1)" "unprognostic (2.28e-1)" "unprognostic (1.21e-1)" "unprognostic (9.99e-3)" "unprognostic (1.01e-3)" "potential prognostic unfavorable (2.77e-4)" "unprognostic (1.10e-2)" "unprognostic (3.04e-2)" "unprognostic (1.15e-1)" "unprognostic (3.72e-2)" "unprognostic (2.82e-1)" "unprognostic (3.89e-1)" "unprognostic (3.12e-1)" "unprognostic (1.07e-1)" "unprognostic (1.70e-1)" "unprognostic (1.44e-1)" "unprognostic (3.97e-2)" "unprognostic (1.21e-3)" "unprognostic (1.43e-1)" "unprognostic (4.14e-2)" "unprognostic (1.43e-1)" "unprognostic (3.04e-3)" DYNLRB2 "DNCL2B, DNLC2B, ROBLD2" ENSG00000168589 "Dynein light chain roadblock-type 2" Q8TF09 16 80540734-80550811 "Predicted intracellular proteins" Transport "Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "choroid plexus: 54.7;fallopian tube: 57.1;testis: 157.8" "Group enriched" "Detected in many" 4 "Early spermatids: 2370.8;Epididymal efferent duct ciliated cells: 768.5;Fallopian tube ciliated cells: 637.5;Late primary spermatocytes: 2421.1;Late spermatids: 1174.1;Respiratory ciliated cells: 729.2" "Cell type enriched" "Detected in many" 7 "ependymal cell: 313.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "breast cancer: 2.7" "Breast - Breast glandular cells, Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 27: Breast cancer - Unknown function" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 7 "unprognostic (1.74e-1)" "unprognostic (8.81e-2)" "unprognostic (4.85e-2)" "unprognostic (7.30e-2)" "potential prognostic favorable (3.04e-5)" "unprognostic (8.34e-3)" "unprognostic (1.19e-2)" "unprognostic (3.50e-3)" "unprognostic (2.18e-1)" "unprognostic (1.14e-2)" "unprognostic (1.84e-1)" "unprognostic (2.01e-1)" "unprognostic (1.85e-1)" "unprognostic (6.57e-3)" "unprognostic (4.82e-1)" "potential prognostic unfavorable (6.81e-4)" "unprognostic (1.37e-1)" DYNLT1 "TCTEL1, Tctex-1, TCTEX1" ENSG00000146425 "Dynein light chain Tctex-type 1" P63172 6 158636474-158644743 "Predicted intracellular proteins" "Cell cycle, Cell division, Cytoplasmic inwards viral transport, Host-virus interaction, Microtubular inwards viral transport, Mitosis, Neurogenesis, Transport, Virus entry into host cell" "Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial ciliated cells: 678.9;Epididymal efferent duct ciliated cells: 627.9;Esophageal apical cells: 1750.9;Esophageal suprabasal cells: 739.4;Fallopian tube ciliated cells: 819.7;Late primary spermatocytes: 657.0;Respiratory ciliated cells: 753.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067502 Approved Cytosol,Acrosome NA Yes "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 22: Epididymis - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 107: Ciliated cells - Cilia assembly & function" 95 "Cytosol, Acrosome" "HPA067502: " "unprognostic (2.08e-2)" "potential prognostic unfavorable (1.35e-5)" "unprognostic (6.04e-2)" "unprognostic (2.16e-1)" "unprognostic (2.08e-1)" "unprognostic (1.26e-1)" "unprognostic (1.37e-1)" "unprognostic (2.15e-1)" "unprognostic (4.77e-2)" "unprognostic (6.69e-2)" "unprognostic (3.76e-2)" "unprognostic (7.19e-2)" "unprognostic (1.12e-2)" "potential prognostic unfavorable (5.04e-7)" "unprognostic (4.22e-3)" "unprognostic (1.49e-1)" "unprognostic (1.86e-1)" "unprognostic (1.55e-2)" "unprognostic (1.15e-1)" "unprognostic (1.96e-1)" "unprognostic (8.46e-2)" "unprognostic (5.78e-3)" "unprognostic (1.57e-1)" "unprognostic (1.35e-1)" "unprognostic (2.70e-1)" "unprognostic (5.74e-2)" "unprognostic (2.43e-1)" "unprognostic (1.75e-1)" "unprognostic (6.13e-2)" "unprognostic (2.86e-1)" "unprognostic (2.73e-2)" DYNLT2 "TCTE3, TCTEX1D3, TCTEX2, Tctex4" ENSG00000184786 "Dynein light chain Tctex-type 2" Q8IZS6 6 169740109-169751587 "Predicted intracellular proteins" Transport "Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 146 "testis: 16.7" "Group enriched" "Detected in some" 8 "Early spermatids: 144.6;Late primary spermatocytes: 316.8" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 1 "unprognostic (1.03e-2)" DYNLT2B "MGC33212, TCTEX1D2" ENSG00000213123 "Dynein light chain Tctex-type 2B" Q8WW35 3 196291219-196318299 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Differentiating spermatogonia: 115.9;Early primary spermatocytes: 347.0;Early spermatids: 198.9;Endometrial ciliated cells: 202.4;Epididymal efferent duct ciliated cells: 360.9;Fallopian tube ciliated cells: 423.9;Late primary spermatocytes: 242.4;Respiratory ciliated cells: 338.8" "Cell type enhanced" "Detected in all" "ependymal cell: 29.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 5 "B-cells: 22.0;dendritic cells: 16.2;T-cells: 25.2" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049555 Approved "Microtubules,Mitotic spindle,Primary cilium,Basal body,Cytosol" Yes NA "Cluster 18: Non-specific - Translation" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 17: Choroid plexus - Cilium" "Cluster 63: Non-specific - Protein processing" "Cluster 107: Ciliated cells - Cilia assembly & function" 28 "Microtubules, Primary cilium" "Mitotic spindle, Basal body, Cytosol" "HPA049555: " "unprognostic (2.58e-3)" "unprognostic (7.55e-3)" "potential prognostic favorable (2.67e-4)" "unprognostic (3.56e-2)" "unprognostic (2.86e-1)" "unprognostic (1.82e-1)" "unprognostic (2.68e-1)" "unprognostic (1.32e-1)" "unprognostic (4.90e-2)" "unprognostic (6.85e-2)" "unprognostic (2.79e-1)" "unprognostic (7.68e-2)" "unprognostic (3.88e-2)" "unprognostic (2.14e-2)" "unprognostic (3.00e-3)" "unprognostic (1.14e-2)" "unprognostic (1.20e-1)" "unprognostic (4.70e-2)" "unprognostic (2.56e-2)" "unprognostic (1.30e-1)" "unprognostic (5.00e-2)" "unprognostic (1.12e-1)" "unprognostic (1.03e-1)" "unprognostic (3.09e-1)" "unprognostic (6.02e-2)" "unprognostic (4.09e-1)" "unprognostic (1.92e-1)" "unprognostic (4.71e-1)" "unprognostic (6.08e-2)" DYNLT3 "TCTE1L, TCTEX1L" ENSG00000165169 "Dynein light chain Tctex-type 3" P51808 X 37836757-37847571 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Transport" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 818.7;Endometrial glandular cells: 399.2;Esophageal apical cells: 999.5;Esophageal suprabasal cells: 476.8;Late primary spermatocytes: 253.1;Late spermatids: 605.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003938 Approved NA NA "Cluster 1: T-cells - Unknown function" "Cluster 36: Brain & Liver - Signaling" "Cluster 1: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 51: Secretory epithelial cells - Mixed function" 24 "HPA003938: " "unprognostic (2.07e-1)" "unprognostic (9.52e-2)" "unprognostic (2.81e-1)" "unprognostic (1.88e-1)" "unprognostic (9.13e-2)" "unprognostic (4.00e-2)" "validated prognostic unfavorable (2.77e-4)" "validated prognostic unfavorable (4.35e-6)" "unprognostic (1.55e-1)" "unprognostic (1.70e-1)" "potential prognostic favorable (4.30e-8)" "unprognostic (7.69e-2)" "unprognostic (1.60e-2)" "unprognostic (3.35e-3)" "unprognostic (1.33e-1)" "unprognostic (1.64e-2)" "unprognostic (1.86e-1)" "unprognostic (8.51e-3)" "unprognostic (3.35e-1)" "unprognostic (5.51e-2)" "unprognostic (4.88e-3)" "unprognostic (9.89e-2)" "unprognostic (1.97e-1)" "unprognostic (4.29e-2)" "unprognostic (1.63e-1)" "unprognostic (1.42e-2)" "unprognostic (1.46e-1)" "unprognostic (8.55e-2)" "unprognostic (8.84e-2)" "unprognostic (2.02e-1)" "unprognostic (8.41e-2)" DYNLT4 TCTEX1D4 ENSG00000188396 "Dynein light chain Tctex-type 4" Q5JR98 1 44805893-44807351 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "choroid plexus: 22.9;fallopian tube: 6.5" "Group enriched" "Detected in some" 8 "Endometrial ciliated cells: 101.3;Epididymal efferent duct ciliated cells: 390.7;Fallopian tube ciliated cells: 220.5;Respiratory ciliated cells: 217.2" "Group enriched" "Detected in some" 12 "choroid plexus epithelial cell: 39.5;ependymal cell: 15.2" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 3.9" "Region enhanced" "Detected in all" "choroid plexus: 43.4" "Immune cell enriched" "Detected in single" 12 "neutrophil: 8.0" "Lineage enriched" "Detected in single" 12 "granulocytes: 8.0" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA050116, HPA062652" Enhanced Supported Vesicles NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 8: Immune cells - Immune response" "Cluster 56: Non-specific - Sensory perception" "Cluster 107: Ciliated cells - Cilia assembly & function" 8 Vesicles "HPA050116: , HPA062652: " "unprognostic (3.62e-2)" "unprognostic (6.80e-3)" "unprognostic (3.76e-2)" "unprognostic (2.52e-2)" "unprognostic (6.08e-2)" "unprognostic (8.29e-2)" "unprognostic (1.42e-1)" "unprognostic (6.52e-2)" "unprognostic (3.18e-2)" "unprognostic (7.66e-3)" "unprognostic (1.68e-1)" "unprognostic (4.59e-2)" "unprognostic (1.60e-1)" DYNLT5 "FLJ40873, TCTEX1D1" ENSG00000152760 "Dynein light chain Tctex-type family member 5" Q8N7M0 1 66752459-66779047 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 12.6;fallopian tube: 8.4" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 195.4;Endometrial ciliated cells: 97.6;Ependymal cells: 840.6;Epididymal efferent duct ciliated cells: 219.5;Fallopian tube ciliated cells: 202.1;Hematopoietic stem cells: 111.1;Mast cells: 69.9;Megakaryocytes: 68.0;Neutrophil progenitors: 67.6;Respiratory ciliated cells: 278.8" "Cell type enriched" "Detected in many" 6 "ependymal cell: 930.8" "Cancer enriched" "Detected in single" 10 "Glioblastoma Multiforme (TCGA): 6.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 14 "Leukemia: 4.0" "Kidney - Endothelial cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA028420 Uncertain NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 3: Choroid plexus - Cilium" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 34: Ciliated cells - Cilia assembly & function" 2 "HPA028420: " "unprognostic (2.16e-1)" "unprognostic (1.32e-3)" "potential prognostic unfavorable (2.77e-4)" "unprognostic (1.32e-3)" DYRK1A "DYRK, DYRK1, MNBH" ENSG00000157540 "Dual specificity tyrosine phosphorylation regulated kinase 1A" Q13627 21 37365573-37526358 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 1182.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015323, HPA015810, HPA015813" Approved Supported "Nucleoplasm,Nuclear speckles,Centrosome,Cytosol" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 47: Leukemia - Hemostasis" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 206 "Nuclear speckles" "Nucleoplasm, Centrosome, Cytosol" "HPA015323: , HPA015810: , HPA015813: " "unprognostic (1.57e-2)" "unprognostic (4.88e-2)" "unprognostic (7.89e-2)" "unprognostic (8.10e-2)" "unprognostic (3.97e-3)" "unprognostic (3.16e-2)" "unprognostic (2.83e-2)" "unprognostic (6.88e-2)" "unprognostic (1.77e-1)" "unprognostic (2.60e-2)" "validated prognostic favorable (4.07e-4)" "validated prognostic favorable (6.51e-4)" "unprognostic (3.80e-1)" "unprognostic (1.14e-1)" "unprognostic (4.25e-2)" "unprognostic (1.23e-1)" "unprognostic (1.13e-1)" "unprognostic (2.27e-1)" "unprognostic (1.48e-1)" "unprognostic (5.48e-2)" "unprognostic (1.71e-1)" "unprognostic (9.40e-2)" "unprognostic (2.18e-1)" "unprognostic (3.03e-2)" "unprognostic (8.10e-2)" "unprognostic (7.62e-2)" "unprognostic (5.79e-2)" "unprognostic (1.67e-1)" "unprognostic (1.49e-1)" "unprognostic (1.45e-1)" "unprognostic (9.74e-2)" DYRK1B MIRK ENSG00000105204 "Dual specificity tyrosine phosphorylation regulated kinase 1B" Q9Y463 19 39825350-39834201 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Diabetes mellitus, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 124.8;testis: 79.9" "Cell type enhanced" "Detected in some" "Astrocytes: 8.4;Bergmann glia: 6.8;Brain excitatory neurons: 8.3;Brain inhibitory neurons: 10.1;Choroid plexus epithelial cells: 17.1;Distal convoluted tubule cells: 8.9;Ependymal cells: 18.3;Late spermatids: 13.8;Loop of henle epithelial cells: 8.9;Oligodendrocyte progenitor cells: 8.4;Oligodendrocytes: 8.4;Other brain neurons: 10.2;Papillary tip epithelial cells: 6.4;Podocytes: 10.8;Proximal tubule cells: 15.2;Renal collecting duct principal cells: 7.1;Renal connecting tubule cells: 6.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028522, HPA028786" Uncertain Supported "Nucleoplasm,Mitotic chromosome" Yes No "Cluster 13: Non-specific - Mitochondria" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 98: Neurons - Neurotransmission & signaling" 51 Nucleoplasm "Mitotic chromosome" "HPA028522: , HPA028786: " "unprognostic (4.38e-3)" "unprognostic (1.51e-1)" "unprognostic (4.14e-1)" "unprognostic (7.03e-2)" "unprognostic (1.60e-1)" "unprognostic (2.77e-1)" "unprognostic (1.17e-1)" "unprognostic (2.61e-2)" "unprognostic (5.93e-3)" "unprognostic (2.64e-1)" "unprognostic (1.27e-2)" "unprognostic (5.31e-2)" "potential prognostic favorable (8.31e-5)" "unprognostic (1.21e-1)" "unprognostic (4.05e-1)" "unprognostic (1.01e-1)" "unprognostic (8.15e-2)" "unprognostic (1.46e-2)" "unprognostic (7.85e-2)" "unprognostic (1.25e-3)" "unprognostic (1.35e-1)" "unprognostic (1.33e-1)" "unprognostic (4.26e-2)" "unprognostic (3.75e-2)" "unprognostic (2.00e-1)" "unprognostic (6.45e-2)" "unprognostic (3.55e-1)" "unprognostic (1.03e-1)" "unprognostic (5.39e-2)" "unprognostic (2.03e-1)" "unprognostic (4.34e-2)" DYRK2 ENSG00000127334 "Dual specificity tyrosine phosphorylation regulated kinase 2" Q92630 12 67648338-67665406 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 86.8;Goblet cells: 81.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027230, HPA056902" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 52: Non-specific - Cellular respiration" "Cluster 29: Forebrain - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 32 Nucleoplasm Cytosol "HPA027230: , HPA056902: " "unprognostic (2.15e-1)" "unprognostic (1.18e-1)" "unprognostic (2.56e-1)" "unprognostic (8.53e-2)" "unprognostic (3.59e-1)" "unprognostic (3.22e-1)" "unprognostic (9.62e-2)" "potential prognostic favorable (4.41e-6)" "unprognostic (1.89e-1)" "unprognostic (6.86e-3)" "potential prognostic favorable (1.27e-5)" "unprognostic (1.47e-3)" "unprognostic (2.38e-1)" "unprognostic (3.22e-3)" "unprognostic (2.07e-1)" "unprognostic (2.54e-2)" "unprognostic (2.32e-2)" "unprognostic (1.00e-2)" "unprognostic (4.65e-1)" "unprognostic (4.17e-2)" "potential prognostic unfavorable (3.00e-4)" "unprognostic (8.32e-3)" "unprognostic (8.11e-2)" "unprognostic (1.79e-1)" "unprognostic (1.48e-2)" "unprognostic (2.27e-1)" "unprognostic (1.23e-2)" "unprognostic (7.94e-2)" "unprognostic (6.09e-2)" "unprognostic (5.05e-2)" "unprognostic (1.98e-1)" DYRK3 "hYAK3-2, RED, REDK" ENSG00000143479 "Dual specificity tyrosine phosphorylation regulated kinase 3" O43781 1 206635536-206684419 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 44.8" "Cell type enhanced" "Detected in many" "Early spermatids: 214.0;Erythrocyte progenitors: 91.0;Late primary spermatocytes: 364.5;Salivary basal cells: 89.8" "Cell type enhanced" "Detected in many" "ependymal cell: 70.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 2.7" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary gland ductal cells, Skeletal muscle - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA075041 Supported Nucleoplasm,Cytosol NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 57: Testis - Spermatogenesis" "Cluster 46: Brainstem - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 103: Non-specific - Basic cellular processes" 1 Nucleoplasm Cytosol "HPA075041: " "unprognostic (1.53e-1)" "unprognostic (1.27e-1)" "unprognostic (1.35e-1)" "unprognostic (6.22e-2)" "unprognostic (8.63e-2)" "unprognostic (1.34e-2)" "unprognostic (7.30e-3)" "unprognostic (6.60e-2)" "unprognostic (3.53e-1)" "unprognostic (1.23e-1)" "potential prognostic favorable (1.25e-5)" "unprognostic (3.62e-2)" "unprognostic (2.16e-2)" "unprognostic (1.73e-3)" "unprognostic (8.45e-3)" "unprognostic (6.23e-3)" "unprognostic (1.11e-2)" "unprognostic (1.49e-2)" "unprognostic (2.81e-1)" "unprognostic (1.44e-1)" "unprognostic (3.22e-3)" "unprognostic (6.55e-2)" "unprognostic (2.11e-2)" "unprognostic (2.87e-1)" "unprognostic (2.19e-1)" "unprognostic (1.04e-2)" "unprognostic (1.64e-1)" "unprognostic (3.20e-1)" "unprognostic (1.36e-1)" "unprognostic (1.55e-3)" "unprognostic (9.38e-2)" DYRK4 ENSG00000010219 "Dual specificity tyrosine phosphorylation regulated kinase 4" Q9NR20 12 4562208-4615302 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 34.3" "Group enriched" "Detected in many" 7 "Early spermatids: 338.6;Late spermatids: 446.7" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 12.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA028065, HPA056073" Enhanced Enhanced Vesicles No No "Cluster 23: B-cells - Immunoglobulins" "Cluster 22: Epididymis - Mixed function" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 38: Non-specific - Transcription" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 9 Vesicles "HPA028065: , HPA056073: " "unprognostic (5.15e-3)" "unprognostic (7.32e-2)" "unprognostic (4.40e-2)" "unprognostic (1.39e-2)" "unprognostic (1.40e-1)" "unprognostic (3.23e-1)" "unprognostic (6.17e-2)" "unprognostic (8.49e-2)" "unprognostic (7.29e-3)" "unprognostic (1.62e-2)" "unprognostic (3.48e-2)" "unprognostic (2.27e-2)" "unprognostic (2.18e-2)" "potential prognostic unfavorable (3.43e-4)" "unprognostic (3.20e-1)" "unprognostic (9.16e-2)" "unprognostic (1.64e-1)" "unprognostic (7.92e-2)" "unprognostic (2.53e-2)" "unprognostic (1.21e-2)" "unprognostic (2.35e-1)" "unprognostic (5.85e-2)" "unprognostic (3.31e-2)" "unprognostic (4.46e-1)" "unprognostic (9.78e-3)" "unprognostic (6.11e-3)" "unprognostic (6.56e-2)" "unprognostic (3.07e-2)" "unprognostic (4.28e-2)" "unprognostic (3.77e-3)" "unprognostic (4.82e-2)" DYSF "FER1L1, LGMD2B" ENSG00000135636 Dysferlin O75923 2 71453561-71686763 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 49.3;skeletal muscle: 119.0" "Cell type enriched" "Detected in many" 4 "Neutrophils: 2844.8" "Cell type enhanced" "Detected in all" "mammillary body: 168.4" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 22.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "neutrophil: 51.7" "Lineage enriched" "Detected in many" 6 "granulocytes: 51.7" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells, Lung - Neutrophils_2, Minor Salivary Gland - Endothelial cells, Spleen - Neutrophils_2, Thyroid gland - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002510, HPA017071, HPA021945" Enhanced Approved "Plasma membrane,Centriolar satellite,Mid piece" Yes No "Cluster 21: Neutrophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 72: Neuronal - Signal transduction" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 47 "Plasma membrane, Centriolar satellite, Mid piece" "CAB002510: , HPA017071: , HPA021945: " "unprognostic (9.90e-2)" "unprognostic (1.32e-1)" "unprognostic (1.34e-1)" "unprognostic (1.21e-2)" "unprognostic (3.84e-2)" "unprognostic (2.45e-1)" "unprognostic (3.29e-1)" "unprognostic (1.01e-1)" "unprognostic (3.32e-1)" "unprognostic (4.09e-1)" "validated prognostic favorable (2.13e-11)" "validated prognostic favorable (7.59e-4)" "unprognostic (3.10e-1)" "unprognostic (2.80e-1)" "unprognostic (5.39e-3)" "unprognostic (7.17e-2)" "unprognostic (1.45e-2)" "unprognostic (7.23e-2)" "unprognostic (5.53e-2)" "unprognostic (4.52e-2)" "unprognostic (2.84e-1)" "unprognostic (2.53e-2)" "unprognostic (8.42e-2)" "unprognostic (7.85e-2)" "unprognostic (3.80e-2)" "unprognostic (6.45e-2)" "unprognostic (1.90e-2)" "unprognostic (4.23e-2)" "unprognostic (5.27e-2)" "unprognostic (6.90e-2)" DYTN ENSG00000232125 Dystrotelin A2CJ06 2 206651621-206721570 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 4 "Hematopoietic stem cells: 201.9" "Cell type enhanced" "Detected in many" "ependymal cell: 11.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Spleen - Neutrophils_2" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" DZANK1 "ANKRD64, bA189K21.8, C20orf12, C20orf84, dJ568F9.2, FLJ10600, FLJ30892" ENSG00000089091 "Double zinc ribbon and ankyrin repeat domains 1" Q9NVP4 20 18383367-18467281 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 99.9;Ependymal cells: 226.4;Fallopian tube ciliated cells: 117.4;Respiratory ciliated cells: 195.3;Somatotrophs: 75.7;Thyrotrophs: 106.9" "Cell type enhanced" "Detected in all" "ependymal cell: 239.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Rhabdoid: 19.9" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059478 Uncertain NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 3: Rhabdoid - Membrane components" "Cluster 34: Ciliated cells - Cilia assembly & function" 2 "HPA059478: " "unprognostic (2.04e-1)" "unprognostic (3.95e-3)" "unprognostic (2.09e-1)" "unprognostic (1.74e-1)" "unprognostic (9.51e-2)" "unprognostic (3.86e-1)" "unprognostic (7.61e-2)" "unprognostic (7.27e-3)" "unprognostic (1.56e-2)" "potential prognostic unfavorable (4.77e-6)" "unprognostic (2.05e-1)" "unprognostic (1.64e-3)" "unprognostic (2.24e-1)" "unprognostic (2.29e-1)" "unprognostic (1.15e-1)" "unprognostic (7.05e-2)" "unprognostic (1.40e-1)" "potential prognostic favorable (4.85e-4)" "potential prognostic favorable (1.17e-4)" "unprognostic (1.87e-2)" "unprognostic (2.12e-1)" "unprognostic (7.31e-3)" "potential prognostic favorable (2.09e-4)" "unprognostic (5.94e-2)" "unprognostic (6.69e-2)" "unprognostic (2.32e-1)" "unprognostic (4.19e-2)" "unprognostic (1.64e-1)" DZIP1 "DZIP, KIAA0996" ENSG00000134874 "DAZ interacting zinc finger protein 1" Q86YF9 13 95578202-95644706 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Differentiation, Spermatogenesis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Early spermatids: 369.3;Late primary spermatocytes: 525.4;Late spermatids: 1213.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 20.6" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Testis - Early spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054891, HPA057272" Uncertain Supported "Nucleoplasm,Centrosome,Basal body,Cytosol" NA NA "Cluster 65: Brain - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 7 "Nucleoplasm, Centrosome, Basal body" Cytosol "HPA054891: , HPA057272: " "unprognostic (1.51e-2)" "unprognostic (2.13e-2)" "unprognostic (2.40e-1)" "unprognostic (1.55e-2)" "unprognostic (4.12e-1)" "unprognostic (3.54e-2)" "unprognostic (4.09e-3)" "unprognostic (3.40e-2)" "validated prognostic favorable (7.33e-4)" "validated prognostic favorable (5.28e-4)" "unprognostic (5.76e-2)" "unprognostic (1.68e-3)" "unprognostic (8.31e-2)" "unprognostic (2.03e-1)" "unprognostic (4.75e-2)" "unprognostic (7.65e-2)" "unprognostic (1.53e-1)" "unprognostic (1.13e-1)" "unprognostic (2.38e-2)" "unprognostic (1.48e-1)" "unprognostic (1.14e-1)" "unprognostic (4.58e-2)" "unprognostic (2.86e-2)" "unprognostic (1.69e-3)" "unprognostic (2.79e-1)" "unprognostic (3.84e-1)" "unprognostic (1.72e-1)" DZIP1L "DZIP2, FLJ32844" ENSG00000158163 "DAZ interacting zinc finger protein 1 like" Q8IYY4 3 138061990-138115818 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 56.6;Endometrial ciliated cells: 123.7;Ependymal cells: 107.1;Fallopian tube ciliated cells: 125.7;Respiratory ciliated cells: 209.8" "Cell type enhanced" "Detected in many" "ependymal cell: 113.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Lung - Respiratory ciliated cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030404 Approved Approved "Nucleoplasm,Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Basal body,Cytosol" Yes No "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 3: Rhabdoid - Membrane components" "Cluster 107: Ciliated cells - Cilia assembly & function" 13 "Microtubules, Cytokinetic bridge, Mitotic spindle, Primary cilium, Basal body" "Nucleoplasm, Cytosol" "HPA030404: " "unprognostic (6.53e-2)" "unprognostic (9.54e-2)" "unprognostic (3.89e-1)" "unprognostic (7.38e-3)" "unprognostic (1.69e-1)" "unprognostic (3.81e-3)" "unprognostic (1.07e-1)" "unprognostic (4.64e-2)" "unprognostic (4.02e-1)" "unprognostic (4.66e-2)" "unprognostic (3.03e-2)" "unprognostic (2.62e-1)" "unprognostic (1.09e-1)" "unprognostic (2.97e-1)" "unprognostic (6.70e-2)" "unprognostic (2.11e-1)" "unprognostic (5.34e-2)" "unprognostic (3.85e-3)" "unprognostic (3.70e-1)" "unprognostic (5.66e-2)" "unprognostic (5.68e-2)" "unprognostic (7.11e-2)" "unprognostic (1.02e-1)" "unprognostic (1.23e-2)" "unprognostic (4.51e-1)" "unprognostic (7.22e-2)" "unprognostic (4.27e-3)" DZIP3 "hRUL138, PPP1R66" ENSG00000198919 "DAZ interacting zinc finger protein 3" Q86Y13 3 108589705-108694840 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 538.2;Corticotrophs: 345.7;Early primary spermatocytes: 416.4;Ependymal cells: 388.4;Gonadotrophs: 398.6;Lactotrophs: 269.6;Respiratory ciliated cells: 412.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Pituitary gland - Lactotropes, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035066, HPA049232" Approved Approved Vesicles No No "Cluster 24: Non-specific - Transcription" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 63: Non-specific - Protein processing" "Cluster 34: Ciliated cells - Cilia assembly & function" 49 Vesicles "HPA035066: , HPA049232: " "unprognostic (2.66e-2)" "unprognostic (1.87e-1)" "unprognostic (3.05e-1)" "unprognostic (1.11e-1)" "unprognostic (1.65e-1)" "unprognostic (4.44e-2)" "unprognostic (4.69e-1)" "unprognostic (1.23e-2)" "unprognostic (1.22e-1)" "unprognostic (3.35e-2)" "potential prognostic favorable (2.48e-7)" "unprognostic (1.03e-2)" "unprognostic (4.39e-2)" "unprognostic (2.33e-1)" "unprognostic (1.22e-1)" "unprognostic (6.58e-3)" "unprognostic (9.41e-2)" "unprognostic (4.25e-1)" "unprognostic (9.84e-2)" "unprognostic (1.89e-1)" "unprognostic (3.10e-2)" "unprognostic (1.07e-2)" "unprognostic (5.12e-2)" "unprognostic (2.90e-1)" "unprognostic (3.20e-3)" "unprognostic (7.38e-3)" "unprognostic (3.05e-1)" "unprognostic (1.11e-1)" "unprognostic (5.69e-2)" "unprognostic (1.06e-2)" "unprognostic (5.38e-2)" E2F1 "RBBP3, RBP3" ENSG00000101412 "E2F transcription factor 1" Q01094 20 33675477-33686385 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Apoptosis, Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 32.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 18.3;Differentiating spermatogonia: 38.2;Early primary spermatocytes: 24.1;Erythrocyte progenitors: 38.0;Megakaryocyte progenitors: 19.8;Monocyte progenitors: 20.7;Neutrophil progenitors: 15.8;Platelets: 142.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB000329, HPA008003, CAB019308, HPA029735" Enhanced Supported Nucleoplasm,Centrosome NA Yes "Cluster 44: Bone marrow - Nuclear processes" "Cluster 34: Non-specific - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 47: Platelets - Hemostasis" 105 Nucleoplasm Centrosome "CAB000329: , CAB019308: , HPA008003: , HPA029735: " "unprognostic (3.32e-1)" "unprognostic (7.30e-2)" "unprognostic (9.45e-2)" "unprognostic (2.83e-2)" "unprognostic (1.96e-1)" "unprognostic (1.11e-1)" "unprognostic (3.08e-2)" "unprognostic (3.09e-2)" "unprognostic (2.48e-2)" "potential prognostic unfavorable (1.15e-6)" "unprognostic (1.10e-3)" "potential prognostic unfavorable (6.62e-5)" "potential prognostic unfavorable (3.71e-4)" "validated prognostic unfavorable (1.27e-4)" "validated prognostic unfavorable (4.86e-7)" "unprognostic (1.30e-3)" "unprognostic (5.91e-3)" "unprognostic (1.63e-1)" "unprognostic (1.84e-2)" "unprognostic (5.05e-2)" "unprognostic (1.14e-2)" "potential prognostic unfavorable (1.29e-4)" "unprognostic (1.86e-3)" "unprognostic (1.25e-2)" "unprognostic (5.68e-2)" "unprognostic (4.45e-3)" "unprognostic (4.72e-2)" "unprognostic (2.09e-2)" "unprognostic (1.60e-1)" "potential prognostic favorable (8.78e-4)" "unprognostic (1.72e-2)" E2F2 E2F-2 ENSG00000007968 "E2F transcription factor 2" Q14209 1 23506438-23531233 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 23.7;esophagus: 8.3;lymphoid tissue: 14.7" "Cell type enriched" "Detected in some" 6 "Late spermatids: 32.5" "Cell type enhanced" "Detected in single" "leukocyte: 2.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "basophil: 4.1" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Myeloma: 22.1" "Adrenal gland - Mitotic cells (Adrenal gland), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in single" "Not detected" "Not detected" CAB016313 Uncertain NA Yes "Cluster 42: Non-specific - Vesicular transport" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 14 "CAB016313: " "unprognostic (9.90e-2)" "unprognostic (4.33e-2)" "unprognostic (6.18e-2)" "unprognostic (1.08e-1)" "unprognostic (1.24e-1)" "unprognostic (5.25e-2)" "unprognostic (4.14e-1)" "unprognostic (1.22e-3)" "potential prognostic favorable (8.26e-4)" "unprognostic (6.25e-3)" "unprognostic (1.51e-1)" "unprognostic (3.77e-2)" "unprognostic (2.73e-2)" "unprognostic (1.95e-1)" "unprognostic (2.21e-1)" "unprognostic (2.26e-2)" "unprognostic (2.94e-2)" "unprognostic (1.87e-2)" "potential prognostic favorable (9.00e-4)" "unprognostic (4.82e-2)" "unprognostic (7.23e-2)" E2F3 ENSG00000112242 "E2F transcription factor 3" O00716 6 20401879-20493714 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Megakaryocyte progenitors: 192.8;Megakaryocyte-Erythroid progenitors: 194.6;Monocyte progenitors: 244.2;Neutrophil progenitors: 366.3;Neutrophils: 916.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Macrophages, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010523, HPA065012" Supported Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 51: Neurons - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 24: Neutrophils - Innate immunity signal integration" 19 Nucleoplasm "HPA010523: , HPA065012: " "unprognostic (3.10e-2)" "unprognostic (1.43e-1)" "unprognostic (2.95e-1)" "unprognostic (1.16e-2)" "unprognostic (4.23e-2)" "unprognostic (1.71e-2)" "unprognostic (1.71e-1)" "unprognostic (5.93e-2)" "unprognostic (1.66e-1)" "unprognostic (1.79e-1)" "unprognostic (1.07e-1)" "unprognostic (4.56e-2)" "unprognostic (1.36e-2)" "unprognostic (3.68e-3)" "unprognostic (1.03e-2)" "unprognostic (5.49e-2)" "unprognostic (1.68e-2)" "unprognostic (4.52e-1)" "unprognostic (7.09e-2)" "unprognostic (2.07e-2)" "unprognostic (1.02e-1)" "unprognostic (1.61e-2)" "unprognostic (6.21e-2)" "unprognostic (8.24e-2)" "unprognostic (8.41e-2)" "unprognostic (1.15e-1)" "unprognostic (3.84e-2)" "unprognostic (1.94e-1)" "unprognostic (4.14e-1)" "unprognostic (8.62e-2)" "unprognostic (1.31e-1)" E2F4 E2F-4 ENSG00000205250 "E2F transcription factor 4" Q16254 16 67192155-67198918 "Predicted intracellular proteins, Transcription factors" "Cell cycle, Cilium biogenesis/degradation, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 136.3;Erythrocyte progenitors: 127.7;Late spermatids: 143.3;Migrating cytotrophoblasts: 129.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054128 Supported Nucleoplasm NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 47 Nucleoplasm "HPA054128: " "unprognostic (4.15e-1)" "unprognostic (4.96e-2)" "unprognostic (1.09e-2)" "unprognostic (2.77e-2)" "unprognostic (3.85e-2)" "unprognostic (4.61e-2)" "unprognostic (2.84e-1)" "potential prognostic favorable (5.47e-5)" "unprognostic (1.93e-3)" "unprognostic (3.18e-1)" "unprognostic (1.84e-1)" "unprognostic (9.19e-2)" "unprognostic (1.51e-1)" "potential prognostic unfavorable (3.17e-5)" "unprognostic (7.89e-2)" "unprognostic (3.42e-2)" "unprognostic (3.66e-2)" "unprognostic (1.74e-3)" "unprognostic (2.50e-2)" "unprognostic (5.95e-2)" "unprognostic (1.71e-1)" "unprognostic (1.81e-1)" "unprognostic (1.20e-3)" "unprognostic (1.78e-3)" "unprognostic (1.76e-1)" "unprognostic (1.75e-1)" "unprognostic (2.01e-1)" "unprognostic (2.51e-1)" "unprognostic (2.71e-1)" "unprognostic (2.75e-1)" "unprognostic (8.02e-3)" E2F5 ENSG00000133740 "E2F transcription factor 5" Q15329 8 85177154-85217158 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Cilium biogenesis/degradation, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 27.7" "Cell type enhanced" "Detected in many" "B-cells: 86.4;Cardiomyocytes: 53.7;Plasma cells: 61.4;Thymocytes: 60.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "memory B-cell: 13.5;naive B-cell: 8.9" "Lineage enriched" "Detected in many" 9 "B-cells: 13.5" "Cancer enhanced" "Detected in all" "lymphoma: 68.0" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055723, HPA065441" Supported Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 39: Astrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 5 Nucleoplasm "Nucleoli, Vesicles" "HPA055723: , HPA065441: " "unprognostic (2.31e-2)" "unprognostic (4.77e-2)" "unprognostic (1.95e-1)" "unprognostic (1.57e-1)" "unprognostic (1.05e-1)" "unprognostic (2.54e-2)" "unprognostic (1.89e-2)" "unprognostic (2.87e-2)" "unprognostic (2.87e-1)" "unprognostic (5.39e-2)" "potential prognostic favorable (2.09e-6)" "unprognostic (1.88e-1)" "unprognostic (2.44e-2)" "validated prognostic unfavorable (1.43e-5)" "validated prognostic unfavorable (6.47e-4)" "unprognostic (1.40e-1)" "unprognostic (6.28e-2)" "unprognostic (1.38e-1)" "unprognostic (2.37e-1)" "unprognostic (1.06e-1)" "unprognostic (3.55e-2)" "unprognostic (1.59e-1)" "unprognostic (2.39e-1)" "unprognostic (6.53e-2)" "unprognostic (4.52e-2)" "unprognostic (2.21e-1)" "unprognostic (2.92e-2)" "unprognostic (6.75e-2)" "unprognostic (5.35e-2)" "unprognostic (3.55e-1)" "unprognostic (1.14e-1)" E2F6 E2F-6 ENSG00000169016 "E2F transcription factor 6" O75461 2 11444375-11466177 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 16 "basophil: 7.8" "Lineage enriched" "Detected in single" 16 "granulocytes: 7.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA075185 Supported Nucleoplasm NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 17: Non-specific - RNA processing" 92 Nucleoplasm "HPA075185: " "unprognostic (4.46e-3)" "unprognostic (7.40e-2)" "unprognostic (6.43e-3)" "unprognostic (2.22e-2)" "unprognostic (6.46e-2)" "unprognostic (1.49e-1)" "unprognostic (3.14e-1)" "unprognostic (2.07e-1)" "unprognostic (1.04e-1)" "unprognostic (2.24e-1)" "unprognostic (8.57e-2)" "unprognostic (1.24e-1)" "unprognostic (9.81e-2)" "validated prognostic unfavorable (3.12e-5)" "validated prognostic unfavorable (5.24e-5)" "unprognostic (1.19e-1)" "unprognostic (3.63e-1)" "unprognostic (3.23e-2)" "unprognostic (1.57e-1)" "unprognostic (1.26e-2)" "unprognostic (1.77e-1)" "potential prognostic favorable (1.47e-4)" "unprognostic (4.20e-3)" "unprognostic (1.95e-2)" "unprognostic (1.50e-2)" "unprognostic (1.14e-1)" "unprognostic (8.07e-2)" "unprognostic (1.87e-1)" "unprognostic (3.81e-1)" "unprognostic (1.92e-1)" "unprognostic (4.85e-2)" E2F7 ENSG00000165891 "E2F transcription factor 7" Q96AV8 12 77021248-77065569 "Predicted intracellular proteins, Transcription factors" "Cell cycle, DNA damage, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.7;lymphoid tissue: 7.7" "Cell type enhanced" "Detected in many" "Early spermatids: 54.3;Endometrial ciliated cells: 47.6;Ependymal cells: 43.8;Late spermatids: 112.0;Monocyte progenitors: 26.0;Respiratory deuterosomal cells: 64.3;Urothelial cells: 58.3" "Cell type enriched" "Detected in some" 19 "ependymal cell: 48.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.8" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Pituitary gland - Corticotropes, Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 8 "midbrain: 8.9;pons: 9.6;thalamus: 16.9" HPA063960 Supported "Nucleoplasm,Primary cilium,Primary cilium tip,Cytosol" NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 46: Brainstem - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 27: Non-specific - Cell proliferation" 6 Nucleoplasm "Primary cilium, Primary cilium tip, Cytosol" "HPA063960: " "unprognostic (6.09e-2)" "unprognostic (2.60e-1)" "unprognostic (2.36e-1)" "unprognostic (1.90e-1)" "unprognostic (1.33e-1)" "unprognostic (3.45e-2)" "unprognostic (3.27e-1)" "unprognostic (1.40e-1)" "unprognostic (3.73e-1)" "potential prognostic unfavorable (5.02e-4)" "validated prognostic unfavorable (1.13e-4)" "validated prognostic unfavorable (4.46e-4)" "unprognostic (2.12e-1)" "unprognostic (3.18e-2)" "unprognostic (4.22e-2)" "unprognostic (2.67e-1)" "potential prognostic unfavorable (1.07e-4)" "unprognostic (1.67e-1)" "unprognostic (6.90e-2)" "unprognostic (2.71e-1)" "unprognostic (4.10e-2)" "unprognostic (1.01e-1)" "unprognostic (9.44e-2)" E2F8 FLJ23311 ENSG00000129173 "E2F transcription factor 8" A0AVK6 11 19224063-19241620 "Predicted intracellular proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 13.4;lymphoid tissue: 11.0;skeletal muscle: 11.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 52.6;Enteric transient amplifying cells: 17.7;Erythrocyte progenitors: 65.0;Gastric chief cells: 16.4;Megakaryocyte progenitors: 24.6;Monocyte progenitors: 66.8;Mucous neck cells: 27.0;Myonuclei: 47.7;Neutrophil progenitors: 31.0;Respiratory deuterosomal cells: 22.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skeletal muscle - Skeletal myocytes, Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA064882, HPA076614" Enhanced Supported Nucleoplasm,Nucleoli,Cytosol No No "Cluster 9: T-regs - Cell cycle regulation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 48: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 17 "Nucleoplasm, Nucleoli" Cytosol "HPA064882: , HPA076614: " "unprognostic (8.07e-2)" "unprognostic (1.59e-1)" "unprognostic (1.93e-1)" "unprognostic (4.88e-2)" "unprognostic (7.83e-2)" "unprognostic (2.22e-2)" "unprognostic (1.74e-1)" "unprognostic (1.24e-1)" "unprognostic (7.67e-3)" "unprognostic (1.78e-2)" "potential prognostic unfavorable (6.44e-4)" "validated prognostic unfavorable (9.89e-6)" "validated prognostic unfavorable (6.61e-5)" "unprognostic (1.23e-3)" "potential prognostic unfavorable (7.58e-5)" "unprognostic (2.23e-1)" "unprognostic (1.26e-1)" "unprognostic (2.44e-1)" "unprognostic (8.46e-2)" "unprognostic (3.12e-3)" "unprognostic (1.21e-2)" "unprognostic (1.96e-3)" "unprognostic (1.59e-1)" "potential prognostic unfavorable (5.60e-4)" "unprognostic (4.87e-3)" "unprognostic (4.61e-1)" "unprognostic (1.72e-1)" E4F1 E4F ENSG00000167967 "E4F transcription factor 1" Q66K89 16 2223580-2235742 "Enzymes, Essential proteins, Predicted intracellular proteins, Transcription factors" "Cell cycle, Cell division, Growth regulation, Host-virus interaction, Mitosis, Transcription, Transcription regulation, Ubl conjugation pathway" "DNA-binding, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069007, HPA071325, HPA072309" Enhanced Supported Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 24: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 65: Non-specific - Cell growth & division" 15 Nucleoplasm "HPA069007: , HPA071325: , HPA072309: " "unprognostic (9.95e-2)" "unprognostic (9.21e-3)" "unprognostic (4.58e-1)" "unprognostic (8.20e-3)" "unprognostic (7.89e-2)" "unprognostic (1.08e-1)" "unprognostic (2.91e-1)" "potential prognostic favorable (6.36e-4)" "unprognostic (5.08e-3)" "unprognostic (5.90e-2)" "unprognostic (1.08e-2)" "unprognostic (2.64e-1)" "unprognostic (2.88e-1)" "unprognostic (1.49e-2)" "unprognostic (9.27e-2)" "unprognostic (1.02e-1)" "unprognostic (9.08e-2)" "unprognostic (1.37e-1)" "unprognostic (3.08e-2)" "unprognostic (2.87e-1)" "unprognostic (1.68e-1)" "unprognostic (5.66e-2)" "unprognostic (1.37e-2)" "unprognostic (1.64e-2)" "unprognostic (1.25e-1)" "unprognostic (3.04e-2)" "unprognostic (2.36e-1)" "unprognostic (1.81e-1)" "unprognostic (1.69e-1)" "unprognostic (3.28e-1)" "unprognostic (1.28e-1)" EAF1 ENSG00000144597 "ELL associated factor 1" Q96JC9 3 15427598-15450635 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 53.9" "Cell type enhanced" "Detected in many" "Early spermatids: 350.1;Late spermatids: 617.0;monocytes: 124.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059516, HPA060569, HPA069538" Supported Approved "Nucleoplasm,Nuclear bodies,Vesicles" NA No "Cluster 5: Non-specific - Cell proliferation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 1: Neurons - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 70 "Nucleoplasm, Nuclear bodies" Vesicles "HPA059516: , HPA060569: , HPA069538: " "unprognostic (2.27e-1)" "unprognostic (9.87e-3)" "unprognostic (4.51e-2)" "unprognostic (1.29e-2)" "unprognostic (2.97e-1)" "unprognostic (9.91e-2)" "unprognostic (4.86e-1)" "unprognostic (8.79e-2)" "unprognostic (1.35e-1)" "potential prognostic unfavorable (4.63e-4)" "potential prognostic favorable (3.85e-4)" "unprognostic (1.72e-2)" "unprognostic (1.54e-2)" "unprognostic (4.37e-2)" "unprognostic (7.78e-3)" "unprognostic (9.44e-3)" "unprognostic (5.08e-3)" "unprognostic (3.13e-3)" "unprognostic (2.55e-1)" "unprognostic (5.62e-2)" "unprognostic (2.55e-2)" "unprognostic (9.58e-2)" "unprognostic (6.04e-2)" "unprognostic (1.19e-1)" "unprognostic (3.55e-2)" "unprognostic (6.62e-2)" "unprognostic (7.11e-2)" "unprognostic (5.49e-2)" "unprognostic (2.83e-1)" "unprognostic (3.14e-3)" "unprognostic (2.77e-1)" EAF2 "BM040, TRAITS, U19" ENSG00000145088 "ELL associated factor 2" Q96CJ1 3 121835183-121886526 "Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 67.8;lymphoid tissue: 50.0" "Cell type enhanced" "Detected in all" "B-cells: 121.8;Hematopoietic stem cells: 119.9;Megakaryocytes: 185.4;Monocyte progenitors: 131.0;Neutrophil progenitors: 216.4;Plasma cells: 365.5;Prostatic glandular cells: 178.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "memory B-cell: 104.8" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in all" 8 "Leukemia: 31.8;lymphoma: 51.9;Myeloma: 61.4" "Adipose visceral - Macrophages, Breast - Plasma cells, Kidney - Proximal tubular cells, Minor Salivary Gland - Plasma cells, Prostate - Prostate glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA008411 Enhanced NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 44: Plasma cells - Antibody production & secretion" 23 "HPA008411: " "unprognostic (9.91e-2)" "unprognostic (3.39e-1)" "unprognostic (3.72e-2)" "potential prognostic favorable (1.02e-4)" "unprognostic (2.68e-1)" "unprognostic (7.68e-2)" "unprognostic (9.88e-2)" "unprognostic (3.98e-2)" "unprognostic (4.63e-2)" "unprognostic (1.99e-1)" "potential prognostic favorable (3.43e-4)" "unprognostic (1.48e-1)" "unprognostic (4.70e-2)" "potential prognostic unfavorable (3.43e-4)" "unprognostic (5.97e-3)" "unprognostic (2.28e-3)" "unprognostic (1.11e-1)" "unprognostic (1.89e-1)" "unprognostic (1.16e-1)" "unprognostic (9.56e-2)" "unprognostic (1.35e-1)" "unprognostic (4.93e-2)" "unprognostic (1.44e-3)" "unprognostic (3.07e-1)" "unprognostic (1.29e-2)" "unprognostic (7.52e-2)" "unprognostic (8.17e-2)" "unprognostic (1.90e-1)" "unprognostic (4.58e-1)" "unprognostic (4.62e-1)" "unprognostic (2.25e-1)" EAPP "BM036, C14orf11, FLJ20578" ENSG00000129518 "E2F associated phosphoprotein" Q56P03 14 34515938-34539704 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002916, HPA071031" Approved Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 49 Nucleoplasm "Nuclear speckles" "HPA002916: , HPA071031: " "unprognostic (1.10e-1)" "unprognostic (1.74e-1)" "unprognostic (1.47e-3)" "unprognostic (4.04e-2)" "unprognostic (6.82e-2)" "unprognostic (2.93e-2)" "unprognostic (1.29e-1)" "unprognostic (3.19e-1)" "unprognostic (9.24e-2)" "unprognostic (1.21e-2)" "potential prognostic favorable (3.28e-8)" "unprognostic (1.07e-3)" "unprognostic (4.52e-2)" "unprognostic (1.38e-1)" "unprognostic (1.07e-1)" "unprognostic (1.40e-1)" "unprognostic (1.79e-1)" "unprognostic (6.87e-3)" "unprognostic (9.06e-2)" "unprognostic (2.72e-1)" "unprognostic (9.77e-2)" "unprognostic (9.96e-2)" "unprognostic (7.70e-2)" "unprognostic (7.81e-2)" "unprognostic (3.95e-2)" "unprognostic (1.32e-2)" "unprognostic (1.53e-1)" "unprognostic (2.19e-2)" "unprognostic (1.59e-1)" "unprognostic (2.94e-2)" "unprognostic (3.33e-2)" EARS2 "KIAA1970, MSE1, mtGlnRS" ENSG00000103356 "Glutamyl-tRNA synthetase 2, mitochondrial" Q5JPH6 16 23520754-23557731 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase, RNA-binding" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043289, HPA043633" Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 54: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 21 Mitochondria Nucleoplasm "HPA043289: , HPA043633: " "unprognostic (8.55e-2)" "unprognostic (4.55e-3)" "unprognostic (5.55e-2)" "unprognostic (9.82e-2)" "unprognostic (1.10e-1)" "unprognostic (4.71e-2)" "unprognostic (3.24e-1)" "unprognostic (2.80e-1)" "unprognostic (3.63e-2)" "unprognostic (3.09e-1)" "unprognostic (7.35e-2)" "unprognostic (2.68e-1)" "unprognostic (2.32e-1)" "unprognostic (4.78e-2)" "unprognostic (4.51e-2)" "unprognostic (2.45e-1)" "unprognostic (4.45e-1)" "unprognostic (1.87e-1)" "unprognostic (4.86e-2)" "unprognostic (2.21e-1)" "unprognostic (4.55e-2)" "unprognostic (2.09e-1)" "unprognostic (3.80e-2)" "unprognostic (2.86e-3)" "unprognostic (7.74e-3)" "unprognostic (1.81e-1)" "unprognostic (7.36e-2)" "unprognostic (3.58e-1)" "unprognostic (1.88e-1)" "unprognostic (8.31e-3)" "unprognostic (2.11e-2)" EBAG9 "EB9, RCAS1" ENSG00000147654 "Estrogen receptor binding site associated antigen 9" O00559 8 109539711-109570072 "Cancer-related genes, Predicted intracellular proteins" Apoptosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 171.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021153, HPA021154, CAB072810, CAB072811, CAB072812" Enhanced Enhanced "Golgi apparatus" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 3: Early primary spermatocytes - Early meiosis" 27 "Golgi apparatus" "CAB072810: , CAB072811: , CAB072812: , HPA021153: , HPA021154: " "unprognostic (2.88e-1)" "unprognostic (2.76e-2)" "unprognostic (2.75e-1)" "unprognostic (3.08e-1)" "unprognostic (7.28e-2)" "unprognostic (3.70e-2)" "unprognostic (8.35e-2)" "unprognostic (1.75e-1)" "unprognostic (3.00e-2)" "unprognostic (4.61e-3)" "potential prognostic favorable (1.70e-8)" "unprognostic (4.54e-3)" "unprognostic (1.91e-1)" "unprognostic (4.34e-1)" "unprognostic (3.52e-2)" "unprognostic (6.19e-3)" "unprognostic (2.93e-1)" "unprognostic (2.76e-1)" "unprognostic (8.98e-2)" "unprognostic (2.61e-1)" "unprognostic (8.21e-3)" "unprognostic (3.09e-2)" "unprognostic (4.39e-2)" "unprognostic (3.23e-1)" "unprognostic (3.88e-1)" "unprognostic (3.36e-1)" "unprognostic (1.92e-2)" "unprognostic (1.88e-1)" "unprognostic (1.97e-1)" "unprognostic (8.07e-2)" "unprognostic (1.59e-1)" EBF1 "COE1, EBF, OLF1" ENSG00000164330 "EBF transcription factor 1" Q9UH73 5 158695916-159099916 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 35.4" "Cell type enhanced" "Detected in many" "Adipocytes: 5390.7;B-cells: 1040.0;Fibro-adipogenic progenitors: 2758.4;Fibroblasts: 888.0;Leydig cells: 2524.6;Pericytes: 1220.5;Peritubular myoid cells: 790.4;Pituitary stem cells: 613.5;Retinal ganglion cells: 1039.1;Vascular smooth muscle cells: 1112.2" "Group enriched" "Detected in many" 4 "endothelial cell: 1015.5;fibroblast: 935.5;pericyte: 3043.0;vascular associated smooth muscle cell: 2855.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 22 "memory B-cell: 12.1;naive B-cell: 10.2" "Lineage enriched" "Detected in single" 24 "B-cells: 12.1" "Cancer enhanced" "Detected in many" "Leukemia: 15.8;lymphoma: 18.1" "Adrenal gland - Fibroblasts, Pituitary gland - Fibroblasts, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061169 Approved Nucleoplasm,Vesicles NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 25: Non-specific - Transcription" "Cluster 6: Leukemia - Signal transduction" "Cluster 89: Adipocytes - Lipid metabolism" 6 Nucleoplasm Vesicles "HPA061169: " "unprognostic (4.31e-3)" "unprognostic (2.03e-1)" "unprognostic (7.43e-2)" "unprognostic (1.08e-2)" "unprognostic (1.76e-1)" "unprognostic (4.08e-2)" "unprognostic (8.42e-2)" "unprognostic (1.22e-3)" "unprognostic (1.80e-3)" "potential prognostic favorable (7.21e-4)" "potential prognostic unfavorable (6.87e-5)" "unprognostic (1.94e-1)" "unprognostic (3.21e-1)" "unprognostic (1.35e-1)" "unprognostic (8.44e-2)" "unprognostic (3.65e-2)" "unprognostic (5.93e-2)" "unprognostic (4.79e-2)" "unprognostic (2.51e-1)" "unprognostic (1.28e-1)" "unprognostic (6.18e-2)" "unprognostic (2.38e-1)" "unprognostic (1.98e-2)" "unprognostic (1.01e-1)" "unprognostic (1.33e-2)" "unprognostic (6.30e-2)" EBF2 "COE2, FLJ11500" ENSG00000221818 "EBF transcription factor 2" Q9HAK2 8 25841725-26045413 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 16.7" "Cell type enhanced" "Detected in many" "Adipocytes: 82.5;Fibro-adipogenic progenitors: 965.5;Fibroblasts: 175.5;Pericytes: 344.3;Renal collecting duct intercalated cells: 99.1;Vascular smooth muscle cells: 152.8" "Cell type enhanced" "Detected in many" "fibroblast: 141.7;splatter: 54.9" "Group enriched" "Detected in many" 5 "Kidney Chromophobe (TCGA): 14.9;Kidney Renal Clear Cell Carcinoma (TCGA): 3.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 16 "Sarcoma: 21.9" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells" "Group enriched" "Detected in many" 4 "basal ganglia: 5.7;cerebellum: 3.1;hypothalamus: 2.0;midbrain: 4.4;pons and medulla: 2.8" "Region enriched" "Detected in many" 5 "spinal cord: 11.4" "HPA003954, HPA055101" Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 54: Non-specific - Transcription" "Cluster 110: Mural cells - ECM organization" 3 Nucleoplasm "Nuclear bodies" "HPA003954: , HPA055101: " "unprognostic (1.10e-1)" "unprognostic (3.99e-1)" "unprognostic (6.93e-2)" "unprognostic (6.76e-2)" "unprognostic (3.31e-1)" "unprognostic (1.89e-1)" "unprognostic (3.44e-3)" "potential prognostic favorable (3.21e-5)" "unprognostic (1.58e-1)" "unprognostic (6.35e-2)" "unprognostic (1.97e-1)" "unprognostic (3.79e-2)" "unprognostic (1.64e-1)" "unprognostic (1.76e-2)" EBF3 "COE3, DKFZp667B0210" ENSG00000108001 "EBF transcription factor 3" Q9H4W6 10 129835233-129973053 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 15.8" "Cell type enhanced" "Detected in some" "Adipocytes: 115.5;Fibro-adipogenic progenitors: 328.8;Fibroblasts: 50.8;Myosatellite cells: 175.2;Oocytes: 46.1;Pericytes: 48.0;Retinal ganglion cells: 123.6;Vascular endothelial cells: 78.6;Vascular smooth muscle cells: 33.3" "Cell type enhanced" "Detected in many" "fibroblast: 38.1;splatter: 89.5" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 35.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 19.1;Neuroblastoma: 10.4" "Breast - Endothelial cells, Kidney - Fibroblasts, Prostate - Endothelial cells, Testis - Spermatogonia, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA061169 Approved Nucleoplasm,Vesicles NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 1 Nucleoplasm Vesicles "HPA061169: " "unprognostic (3.28e-1)" "potential prognostic favorable (5.88e-4)" "unprognostic (8.30e-2)" "unprognostic (2.88e-1)" "unprognostic (6.35e-3)" "validated prognostic favorable (2.09e-4)" "validated prognostic favorable (1.11e-4)" "unprognostic (1.08e-1)" "unprognostic (4.31e-2)" "unprognostic (4.77e-2)" "unprognostic (4.14e-2)" "unprognostic (1.03e-1)" "unprognostic (1.21e-2)" "unprognostic (2.86e-1)" "unprognostic (5.56e-2)" EBF4 "COE4, KIAA1442, O/E-4, RP5-860F19.3" ENSG00000088881 "EBF family member 4" Q9BQW3 20 2692780-2760108 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 58.0;Endometrial stromal cells: 52.7;Oligodendrocyte progenitor cells: 94.3;Somatotrophs: 68.1" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 91.2;oligodendrocyte precursor cell: 106.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 15.8" "Adipose subcutaneous - Smooth muscle cells, Breast - Breast glandular cells, Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" "unprognostic (3.88e-3)" "unprognostic (1.86e-2)" "unprognostic (3.49e-1)" "unprognostic (6.83e-3)" "unprognostic (6.09e-3)" "unprognostic (1.21e-1)" "unprognostic (2.80e-2)" "unprognostic (1.07e-2)" "unprognostic (7.68e-2)" "unprognostic (1.96e-1)" "unprognostic (1.68e-1)" "unprognostic (2.15e-3)" "unprognostic (6.04e-2)" "unprognostic (4.09e-2)" "unprognostic (2.09e-3)" "unprognostic (1.78e-1)" "unprognostic (2.80e-1)" "unprognostic (2.78e-2)" "unprognostic (4.86e-2)" "unprognostic (2.86e-1)" "unprognostic (1.21e-3)" "potential prognostic favorable (3.82e-4)" "unprognostic (2.76e-1)" "unprognostic (2.56e-2)" "unprognostic (1.61e-1)" "unprognostic (1.08e-1)" "potential prognostic unfavorable (1.75e-4)" "unprognostic (4.37e-3)" "unprognostic (2.35e-1)" "unprognostic (5.55e-3)" "unprognostic (2.37e-2)" EBI3 "IL27B, IL35B" ENSG00000105246 "Epstein-Barr virus induced 3" Q14213 19 4229523-4237528 "Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "placenta: 138.8" "Cell type enhanced" "Detected in some" "cDC: 71.9;Extravillous trophoblasts: 973.7;Kupffer cells: 220.4;Macrophages: 61.9;Migrating cytotrophoblasts: 81.8;Syncytiotrophoblasts: 442.1" "Cell type enriched" "Detected in some" 32 "central nervous system macrophage: 52.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "intermediate monocyte: 4.9;memory B-cell: 18.7;naive B-cell: 14.8;non-classical monocyte: 6.4" "Group enriched" "Detected in many" 14 "B-cells: 18.7;monocytes: 6.4" "Cancer enriched" "Detected in many" 4 "lymphoma: 69.9" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Spleen - Macrophages, Stomach - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA046635 Enhanced "Secreted to blood" Cytokine NA NA 203000 490000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." "HPA046635: " "unprognostic (1.72e-1)" "unprognostic (3.63e-2)" "unprognostic (6.86e-2)" "unprognostic (4.08e-2)" "unprognostic (2.66e-1)" "unprognostic (2.29e-1)" "unprognostic (2.09e-1)" "unprognostic (5.44e-3)" "unprognostic (5.63e-2)" "unprognostic (5.87e-2)" "potential prognostic unfavorable (3.66e-4)" "unprognostic (2.72e-2)" "potential prognostic unfavorable (7.99e-4)" "unprognostic (6.42e-2)" "unprognostic (4.42e-2)" "unprognostic (1.36e-1)" "unprognostic (4.74e-2)" "unprognostic (7.73e-3)" "unprognostic (1.76e-2)" "unprognostic (1.78e-1)" "unprognostic (3.98e-1)" "unprognostic (4.69e-3)" "unprognostic (2.09e-3)" "unprognostic (1.89e-1)" "unprognostic (8.87e-2)" "unprognostic (7.83e-3)" "unprognostic (3.77e-2)" "unprognostic (4.19e-1)" "unprognostic (7.01e-2)" "unprognostic (1.20e-1)" "unprognostic (4.31e-2)" EBLN1 ENSG00000223601 "Endogenous Bornavirus like nucleoprotein 1" P0CF75 10 22208475-22218015 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 10 "testis: 1.9" "Group enriched" "Detected in some" 15 "Early spermatids: 17.6;Late primary spermatocytes: 23.8;Late spermatids: 12.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" NA NA "Cluster 47: Testis - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" EBLN2 ENSG00000255423 "Endogenous Bornavirus like nucleoprotein 2" Q6P2I7 3 73061659-73063337 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 4 "bone marrow: 14.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "HPA062510, HPA068795" Uncertain Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 15: Bone marrow - Innate immune response" "Cluster 11: White matter - Signal transduction" "Cluster 56: Non-specific - Sensory perception" 2 "Nuclear bodies" Nucleoplasm "HPA062510: , HPA068795: " "unprognostic (1.82e-3)" "unprognostic (1.53e-1)" "unprognostic (8.16e-2)" "unprognostic (4.01e-2)" "unprognostic (1.23e-2)" "unprognostic (7.99e-3)" "unprognostic (2.86e-3)" "unprognostic (1.54e-3)" "unprognostic (1.40e-1)" "unprognostic (2.80e-1)" EBNA1BP2 "EBP2, NOBP, P40" ENSG00000117395 "EBNA1 binding protein 2" Q99848 1 43164175-43270936 "Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 396.9;Proximal tubule cells: 388.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in all" 5 "Adrenocortical cancer: 1042.1" "Pituitary gland - Somatotropes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026512, HPA028277" Approved Enhanced "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No 9300 "Cluster 13: Non-specific - Mitochondria" "Cluster 70: Non-specific - Protein processing" "Cluster 23: Choroid plexus - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 88: Proximal tubular cells - Transmembrane transport" 74 "Nucleoli, Nucleoli rim" "Mitotic chromosome" "HPA026512: , HPA028277: " "unprognostic (5.44e-3)" "unprognostic (6.34e-2)" "unprognostic (2.78e-2)" "unprognostic (1.62e-1)" "unprognostic (2.18e-2)" "unprognostic (2.84e-1)" "unprognostic (7.20e-2)" "unprognostic (4.13e-2)" "unprognostic (3.21e-2)" "unprognostic (1.19e-3)" "potential prognostic favorable (2.91e-4)" "unprognostic (3.11e-1)" "unprognostic (3.46e-2)" "potential prognostic unfavorable (1.42e-8)" "unprognostic (5.30e-2)" "unprognostic (3.84e-2)" "unprognostic (1.73e-3)" "unprognostic (8.48e-2)" "unprognostic (2.30e-1)" "unprognostic (2.56e-2)" "unprognostic (9.43e-3)" "unprognostic (3.42e-2)" "unprognostic (5.18e-2)" "unprognostic (1.64e-3)" "unprognostic (1.28e-1)" "unprognostic (4.40e-2)" "unprognostic (2.49e-1)" "unprognostic (3.56e-2)" "unprognostic (3.00e-1)" "unprognostic (1.87e-1)" "unprognostic (1.89e-1)" EBP "CDPX2, CHO2, CPX, CPXD" ENSG00000147155 "EBP cholestenol delta-isomerase" Q15125 X 48521799-48528716 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "Hydrolase, Isomerase" "Cataract, Disease variant, Dwarfism, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 307.1" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 9.0;Brain excitatory neurons: 13.9;Brain inhibitory neurons: 14.7;Hepatocytes: 9.4;Loop of henle epithelial cells: 8.3;Oligodendrocyte progenitor cells: 10.2;Other brain neurons: 13.8;Papillary tip epithelial cells: 8.6;Parietal cells: 12.4;Proximal tubule cells: 11.2;Renal collecting duct intercalated cells: 8.3;Renal collecting duct principal cells: 8.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003130 Approved Supported "Nuclear membrane,Endoplasmic reticulum" NA Yes "Cluster 5: Non-specific - Cell proliferation" "Cluster 76: Non-specific - Metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 98: Neurons - Neurotransmission & signaling" 164 "Nuclear membrane, Endoplasmic reticulum" "HPA003130: " "unprognostic (5.50e-2)" "unprognostic (1.83e-2)" "unprognostic (1.08e-2)" "unprognostic (7.48e-2)" "unprognostic (3.99e-1)" "unprognostic (1.38e-1)" "unprognostic (2.24e-1)" "unprognostic (1.90e-2)" "unprognostic (1.11e-1)" "unprognostic (3.69e-3)" "potential prognostic favorable (2.94e-4)" "potential prognostic unfavorable (8.33e-4)" "unprognostic (1.29e-1)" "unprognostic (5.61e-2)" "unprognostic (2.59e-2)" "unprognostic (4.85e-3)" "unprognostic (6.86e-2)" "unprognostic (1.02e-1)" "unprognostic (3.48e-2)" "unprognostic (2.26e-1)" "unprognostic (6.69e-3)" "unprognostic (9.43e-3)" "unprognostic (4.89e-2)" "unprognostic (1.59e-1)" "unprognostic (3.51e-1)" "unprognostic (1.72e-1)" "unprognostic (4.34e-2)" "unprognostic (2.11e-1)" "unprognostic (2.02e-1)" "unprognostic (1.22e-1)" "unprognostic (5.82e-2)" EBPL EBRP ENSG00000123179 "EBP like" Q9BY08 13 49660674-49691486 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 92.8" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 383.8;Esophageal suprabasal cells: 509.7;Hepatocytes: 349.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049891 Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 19: Non-specific - Unknown function" "Cluster 85: Squamous epithelial cells - Keratinization" "Endoplasmic reticulum" "HPA049891: " "unprognostic (2.12e-2)" "unprognostic (3.26e-1)" "unprognostic (2.36e-1)" "potential prognostic unfavorable (4.73e-4)" "unprognostic (4.46e-2)" "unprognostic (1.33e-1)" "unprognostic (2.62e-1)" "unprognostic (1.01e-1)" "unprognostic (2.18e-3)" "unprognostic (1.45e-3)" "unprognostic (3.58e-3)" "unprognostic (2.28e-2)" "unprognostic (7.27e-3)" "unprognostic (2.87e-2)" "unprognostic (5.76e-2)" "unprognostic (2.11e-2)" "unprognostic (3.07e-2)" "unprognostic (7.43e-2)" "unprognostic (5.13e-2)" "unprognostic (1.08e-3)" "unprognostic (1.89e-2)" "unprognostic (5.39e-3)" "potential prognostic unfavorable (5.31e-5)" "unprognostic (8.66e-2)" "unprognostic (2.50e-2)" "unprognostic (2.45e-1)" "unprognostic (7.54e-2)" "unprognostic (5.84e-2)" "unprognostic (2.00e-1)" "unprognostic (1.87e-1)" "unprognostic (5.08e-2)" ECD "GCR2, hSGT1" ENSG00000122882 "Ecdysoneless cell cycle regulator" O95905 10 73130155-73169055 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006465 Approved Supported Nucleoplasm,Cytosol Yes No "Cluster 28: Neutrophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 55 "Nucleoplasm, Cytosol" "HPA006465: " "unprognostic (1.72e-2)" "unprognostic (3.65e-2)" "unprognostic (3.83e-1)" "unprognostic (4.48e-2)" "unprognostic (1.60e-1)" "unprognostic (8.52e-2)" "unprognostic (1.06e-1)" "potential prognostic favorable (1.07e-6)" "unprognostic (6.99e-2)" "potential prognostic unfavorable (4.79e-5)" "unprognostic (1.38e-3)" "unprognostic (2.06e-2)" "unprognostic (1.94e-1)" "unprognostic (2.22e-3)" "unprognostic (1.60e-1)" "unprognostic (7.64e-2)" "unprognostic (1.80e-2)" "unprognostic (9.68e-2)" "unprognostic (8.39e-2)" "unprognostic (4.41e-2)" "unprognostic (1.06e-1)" "unprognostic (1.59e-2)" "unprognostic (4.50e-3)" "unprognostic (3.33e-1)" "unprognostic (5.26e-3)" "unprognostic (6.89e-2)" "unprognostic (2.20e-1)" "unprognostic (1.75e-1)" "unprognostic (2.77e-1)" "unprognostic (1.50e-1)" "unprognostic (3.79e-1)" ECE1 ECE ENSG00000117298 "Endothelin converting enzyme 1" P42892 1 21217247-21345572 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant, Hirschsprung disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Neutrophils: 1703.1" "Cell type enhanced" "Detected in all" "pericyte: 258.7;vascular associated smooth muscle cell: 277.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 29.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Kidney - Endothelial cells, Lung - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001490, HPA013616" Enhanced NA NA 470000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 12 "HPA001490: , HPA013616: " "unprognostic (6.73e-2)" "unprognostic (4.34e-2)" "unprognostic (1.00e-2)" "unprognostic (5.49e-2)" "unprognostic (1.40e-2)" "unprognostic (2.86e-1)" "unprognostic (5.34e-2)" "unprognostic (1.97e-2)" "unprognostic (2.51e-1)" "unprognostic (5.01e-2)" "unprognostic (2.24e-2)" "unprognostic (2.10e-2)" "unprognostic (2.02e-1)" "unprognostic (5.62e-2)" "unprognostic (6.76e-2)" "unprognostic (6.83e-2)" "potential prognostic unfavorable (2.60e-4)" "unprognostic (7.12e-2)" "unprognostic (3.96e-2)" "unprognostic (1.76e-3)" "unprognostic (5.16e-2)" "unprognostic (2.70e-1)" "unprognostic (1.22e-1)" "unprognostic (2.63e-1)" "unprognostic (2.04e-1)" "unprognostic (5.95e-3)" "unprognostic (9.35e-2)" "unprognostic (1.13e-1)" "unprognostic (2.52e-1)" "unprognostic (5.66e-2)" "unprognostic (3.49e-1)" ECE2 "KIAA0604, MGC2408" ENSG00000145194 "Endothelin converting enzyme 2" P0DPD6 3 184276011-184293031 "Enzymes, Predicted membrane proteins" "Hydrolase, Metalloprotease, Methyltransferase, Multifunctional enzyme, Protease, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 58.1;pancreas: 24.1;pituitary gland: 19.1" "Cell type enhanced" "Detected in some" "Astrocytes: 16.5;Bergmann glia: 19.9;Brain excitatory neurons: 46.5;Brain inhibitory neurons: 93.3;Oligodendrocyte progenitor cells: 43.8;Other brain neurons: 126.2" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in some" 5 "Glioblastoma Multiforme (TCGA): 5.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Neuroblastoma: 1.1" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 70: Non-specific - Protein processing" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" "unprognostic (2.33e-1)" "unprognostic (1.08e-3)" "unprognostic (3.35e-1)" "potential prognostic unfavorable (8.66e-9)" "unprognostic (2.27e-1)" "unprognostic (6.45e-3)" "unprognostic (9.50e-3)" ECEL1 "DINE, XCE" ENSG00000171551 "Endothelin converting enzyme like 1" O95672 2 232479827-232487834 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 84.5;ovary: 97.5;pituitary gland: 28.1" "Cell type enhanced" "Detected in some" "Corticotrophs: 10.7;Lactotrophs: 9.0;Müller glia: 109.4;Other brain neurons: 62.6;Ovarian stromal cells: 9.0;Peritubular myoid cells: 21.0;Retinal bipolar cells: 22.7;Somatotrophs: 16.9;Thyrotrophs: 8.7" "Cell type enriched" "Detected in many" 5 "splatter: 16.1" "Cancer enriched" "Detected in many" 4 "Uterine Corpus Endometrial Carcinoma (TCGA): 31.4" "Region enhanced" "Detected in all" "hypothalamus: 235.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "head and neck cancer: 13.8" "Region enhanced" "Detected in many" "hypothalamus: 70.7" "Low region specificity" "Detected in many" "HPA067560, HPA069756, HPA077424" Approved Supported Uncertain "Nucleoplasm,Nuclear membrane,Nucleoli" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 65: Non-specific - Unknown function" "Cluster 11: Muller glia cells - Retinal homeostasis" 54 Nucleoplasm "Nuclear membrane, Nucleoli" "HPA067560: , HPA069756: , HPA077424: " "unprognostic (3.33e-2)" "unprognostic (1.51e-2)" "unprognostic (1.61e-2)" "unprognostic (4.77e-3)" "unprognostic (3.37e-1)" "unprognostic (9.71e-3)" "unprognostic (1.83e-3)" "unprognostic (1.40e-2)" "unprognostic (4.54e-2)" "unprognostic (6.52e-3)" "unprognostic (1.34e-1)" "unprognostic (3.54e-2)" "unprognostic (2.83e-2)" "unprognostic (2.83e-1)" "unprognostic (3.33e-1)" "unprognostic (1.54e-1)" "unprognostic (1.24e-2)" "unprognostic (3.69e-2)" "unprognostic (2.40e-2)" "unprognostic (4.15e-2)" "unprognostic (1.73e-1)" "unprognostic (2.24e-1)" "unprognostic (1.32e-1)" ECH1 HPXEL ENSG00000104823 "Enoyl-CoA hydratase 1" Q13011 19 38815422-38831841 "Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 769.1;skeletal muscle: 904.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 384.9;Extravillous trophoblasts: 201.6;Migrating cytotrophoblasts: 332.5;Syncytiotrophoblasts: 278.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002907, HPA005835" Supported Supported Supported Mitochondria No No 1300000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 29 Mitochondria "HPA002907: , HPA005835: " "unprognostic (1.59e-1)" "unprognostic (4.73e-2)" "potential prognostic unfavorable (4.54e-5)" "unprognostic (1.59e-1)" "unprognostic (1.34e-1)" "unprognostic (8.66e-2)" "unprognostic (1.49e-1)" "unprognostic (8.56e-2)" "unprognostic (1.70e-1)" "unprognostic (3.37e-1)" "potential prognostic favorable (5.12e-8)" "unprognostic (7.17e-3)" "unprognostic (4.06e-3)" "unprognostic (1.84e-1)" "unprognostic (9.17e-2)" "unprognostic (4.18e-3)" "unprognostic (6.08e-3)" "unprognostic (4.05e-2)" "unprognostic (1.65e-2)" "unprognostic (1.34e-2)" "unprognostic (2.67e-1)" "unprognostic (3.80e-2)" "unprognostic (2.45e-1)" "unprognostic (1.90e-1)" "unprognostic (2.58e-1)" "unprognostic (1.43e-1)" "unprognostic (3.72e-2)" "potential prognostic unfavorable (2.93e-4)" "unprognostic (1.15e-1)" "unprognostic (9.45e-2)" "unprognostic (4.82e-2)" ECHDC1 dJ351K20.2 ENSG00000093144 "Ethylmalonyl-CoA decarboxylase 1" Q9NTX5 6 127288712-127343609 "Enzymes, Plasma proteins, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 310.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035445, HPA035446" Uncertain Approved Vesicles NA NA 33000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 28: Non-specific - Nuclear processes" "Cluster 89: Adipocytes - Lipid metabolism" 2 Vesicles "HPA035445: , HPA035446: " "unprognostic (3.73e-1)" "unprognostic (1.22e-1)" "unprognostic (3.92e-2)" "unprognostic (6.44e-3)" "unprognostic (2.25e-3)" "unprognostic (1.95e-2)" "unprognostic (1.27e-1)" "unprognostic (2.52e-2)" "unprognostic (1.30e-1)" "potential prognostic unfavorable (5.35e-5)" "potential prognostic favorable (9.33e-7)" "unprognostic (3.84e-2)" "unprognostic (1.27e-1)" "potential prognostic unfavorable (1.20e-4)" "unprognostic (4.86e-3)" "unprognostic (4.55e-2)" "unprognostic (4.05e-2)" "unprognostic (8.54e-2)" "unprognostic (1.85e-1)" "unprognostic (1.74e-1)" "unprognostic (1.76e-1)" "unprognostic (6.41e-2)" "unprognostic (3.24e-1)" "unprognostic (9.02e-2)" "unprognostic (2.12e-2)" "unprognostic (2.05e-1)" "unprognostic (4.28e-2)" "unprognostic (2.10e-1)" "unprognostic (1.37e-1)" "unprognostic (3.06e-1)" "unprognostic (1.61e-2)" ECHDC2 FLJ10948 ENSG00000121310 "Enoyl-CoA hydratase domain containing 2" Q86YB7 1 52895910-52927212 "Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 174.8" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 654.9;Hepatocytes: 1510.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026731, HPA026768" Enhanced Approved Mitochondria NA NA 210000 "Cluster 33: Non-specific - ATP binding" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 15: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 93: Hepatocytes - Bile production & excretion" 7 Mitochondria "HPA026731: , HPA026768: " "unprognostic (3.13e-1)" "unprognostic (1.13e-1)" "unprognostic (9.30e-2)" "unprognostic (4.40e-2)" "unprognostic (3.78e-2)" "unprognostic (1.40e-1)" "unprognostic (3.19e-2)" "unprognostic (2.52e-2)" "unprognostic (5.42e-3)" "unprognostic (1.03e-1)" "potential prognostic favorable (5.05e-7)" "unprognostic (8.42e-2)" "unprognostic (1.25e-3)" "potential prognostic favorable (8.62e-4)" "unprognostic (2.40e-3)" "unprognostic (2.27e-2)" "unprognostic (7.83e-2)" "unprognostic (1.92e-1)" "unprognostic (3.32e-2)" "unprognostic (2.55e-1)" "unprognostic (1.77e-2)" "unprognostic (1.59e-1)" "unprognostic (1.22e-1)" "unprognostic (3.20e-1)" "unprognostic (9.91e-2)" "unprognostic (4.17e-3)" "unprognostic (5.06e-2)" "unprognostic (1.17e-2)" "unprognostic (1.11e-1)" "unprognostic (5.84e-2)" "unprognostic (1.89e-1)" ECHDC3 FLJ20909 ENSG00000134463 "Enoyl-CoA hydratase domain containing 3" Q96DC8 10 11742366-11764070 "Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 157.5;skeletal muscle: 122.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 108.2;Cytotrophoblasts: 105.2;Esophageal apical cells: 120.4;Hepatocytes: 173.0;Migrating cytotrophoblasts: 84.7;Neutrophils: 217.7;Parietal cells: 93.7;Thymic myoid cells: 406.5" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 13.2;fibroblast: 21.3" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "choroid plexus: 33.6" "Immune cell enriched" "Detected in many" 4 "eosinophil: 15.5" "Lineage enriched" "Detected in many" 9 "granulocytes: 15.5" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA038306 Enhanced NA NA 170000 "Cluster 19: Eosinophils - Unknown function" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 36: Choroid plexus - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 6 "HPA038306: " "potential prognostic unfavorable (4.09e-4)" "potential prognostic unfavorable (4.36e-4)" "unprognostic (3.33e-1)" "unprognostic (2.27e-1)" "unprognostic (2.65e-1)" "unprognostic (8.66e-2)" "unprognostic (3.19e-2)" "unprognostic (1.88e-2)" "unprognostic (1.80e-2)" "unprognostic (5.26e-3)" "potential prognostic favorable (5.56e-9)" "unprognostic (4.43e-2)" "unprognostic (8.78e-2)" "unprognostic (1.05e-1)" "unprognostic (2.24e-2)" "unprognostic (6.04e-2)" "unprognostic (2.40e-1)" "unprognostic (1.15e-2)" "unprognostic (6.05e-2)" "unprognostic (4.66e-2)" "unprognostic (1.19e-1)" "unprognostic (1.02e-1)" "unprognostic (3.18e-3)" "unprognostic (2.34e-1)" "unprognostic (2.11e-1)" "unprognostic (2.42e-2)" "unprognostic (2.43e-1)" "unprognostic (3.75e-2)" "unprognostic (2.91e-1)" "unprognostic (6.87e-2)" "unprognostic (6.02e-2)" ECHS1 SCEH ENSG00000127884 "Enoyl-CoA hydratase, short chain 1" P30084 10 133362485-133373354 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Lyase" "Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1285.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 583.4;Esophageal apical cells: 621.3;Esophageal suprabasal cells: 449.0;Hepatocytes: 1715.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003783, HPA021995, HPA022476" Enhanced Enhanced Mitochondria NA NA 1000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 52: Non-specific - Mitochondria" "Cluster 93: Hepatocytes - Bile production & excretion" 24 Mitochondria "CAB003783: , HPA021995: , HPA022476: " "unprognostic (1.02e-2)" "unprognostic (1.27e-2)" "unprognostic (3.49e-1)" "unprognostic (2.88e-2)" "unprognostic (4.02e-1)" "unprognostic (1.22e-1)" "unprognostic (2.69e-1)" "unprognostic (1.79e-2)" "unprognostic (5.28e-2)" "unprognostic (1.89e-1)" "potential prognostic favorable (2.89e-5)" "unprognostic (1.98e-1)" "unprognostic (1.61e-2)" "unprognostic (6.28e-3)" "unprognostic (2.24e-3)" "unprognostic (2.84e-1)" "unprognostic (9.70e-2)" "unprognostic (2.75e-1)" "unprognostic (3.09e-2)" "unprognostic (5.45e-2)" "unprognostic (3.39e-1)" "unprognostic (1.34e-1)" "unprognostic (3.50e-2)" "unprognostic (7.90e-2)" "unprognostic (2.70e-2)" "unprognostic (2.34e-2)" "unprognostic (4.40e-3)" "unprognostic (2.36e-2)" "unprognostic (9.27e-2)" "unprognostic (2.59e-2)" "unprognostic (3.50e-2)" ECI1 DCI ENSG00000167969 "Enoyl-CoA delta isomerase 1" P42126 16 2239402-2252300 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 298.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041746, HPA043227" Enhanced Enhanced Mitochondria NA NA 3100000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 70: Non-specific - Protein processing" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 54: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" Mitochondria "HPA041746: , HPA043227: " "unprognostic (2.60e-2)" "unprognostic (2.12e-1)" "potential prognostic favorable (3.16e-4)" "unprognostic (3.14e-2)" "unprognostic (3.87e-2)" "unprognostic (1.25e-1)" "unprognostic (4.08e-3)" "unprognostic (3.70e-2)" "potential prognostic favorable (5.89e-4)" "potential prognostic favorable (6.86e-6)" "unprognostic (4.10e-2)" "potential prognostic favorable (3.88e-4)" "unprognostic (5.50e-3)" "unprognostic (2.76e-2)" "unprognostic (5.68e-2)" "unprognostic (2.27e-1)" "unprognostic (2.13e-1)" "unprognostic (1.56e-1)" "unprognostic (2.81e-1)" "unprognostic (1.41e-2)" "unprognostic (8.46e-2)" "unprognostic (1.19e-1)" "unprognostic (2.53e-2)" "unprognostic (3.99e-2)" "unprognostic (2.51e-1)" "unprognostic (1.78e-1)" "unprognostic (5.06e-2)" "unprognostic (2.46e-1)" "unprognostic (5.57e-2)" "unprognostic (1.38e-1)" ECI2 "ACBD2, DRS1, HCA88, PECI" ENSG00000198721 "Enoyl-CoA delta isomerase 2" O75521 6 4115693-4135597 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 395.0" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 373.9;Hepatocytes: 216.0;Migrating cytotrophoblasts: 205.9;Parietal cells: 245.7;Respiratory ciliated cells: 205.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022130, HPA031626" Enhanced Enhanced Peroxisomes,Mitochondria NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 72: Neuronal - Signal transduction" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 14 "Peroxisomes, Mitochondria" "HPA022130: , HPA031626: " "unprognostic (9.35e-2)" "unprognostic (3.06e-1)" "unprognostic (1.62e-1)" "unprognostic (2.24e-2)" "unprognostic (1.89e-1)" "unprognostic (1.23e-3)" "unprognostic (3.38e-2)" "unprognostic (1.74e-3)" "unprognostic (3.58e-2)" "potential prognostic favorable (6.74e-10)" "unprognostic (6.39e-2)" "potential prognostic favorable (5.03e-4)" "unprognostic (1.19e-2)" "unprognostic (5.32e-3)" "unprognostic (2.42e-1)" "unprognostic (6.89e-2)" "unprognostic (4.78e-2)" "unprognostic (3.04e-2)" "potential prognostic favorable (5.07e-4)" "unprognostic (3.40e-1)" "unprognostic (2.53e-2)" "unprognostic (6.23e-2)" "unprognostic (3.06e-2)" "unprognostic (7.94e-2)" "unprognostic (5.19e-2)" "unprognostic (1.22e-1)" "unprognostic (1.55e-1)" "unprognostic (1.81e-1)" "unprognostic (1.20e-1)" "unprognostic (5.07e-2)" ECM1 ENSG00000143369 "Extracellular matrix protein 1" Q16610 1 150508062-150513789 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Angiogenesis, Biomineralization, Mineral balance, Osteogenesis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 457.0;esophagus: 1332.1" "Cell type enriched" "Detected in many" 76 "Esophageal apical cells: 29206.8" "Cell type enhanced" "Detected in all" "pericyte: 47.5" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 275.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 178.2" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Adrenal gland - Fibroblasts, Colon - Fibroblasts, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Pituitary gland - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027241, HPA076029" Enhanced Approved Nucleoplasm,Cytosol "Secreted to extracellular matrix" "Developmental protein" NA NA 3900000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 24: Neurons - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 84: Apical squamous epithelium - Cornification" 27 Cytosol Nucleoplasm "HPA027241: , HPA076029: " "unprognostic (3.43e-1)" "unprognostic (3.75e-2)" "unprognostic (1.51e-1)" "unprognostic (7.20e-2)" "unprognostic (1.57e-1)" "unprognostic (1.46e-1)" "unprognostic (2.34e-1)" "unprognostic (1.96e-1)" "unprognostic (1.56e-2)" "unprognostic (5.43e-2)" "unprognostic (2.99e-3)" "unprognostic (2.04e-1)" "unprognostic (1.54e-2)" "unprognostic (2.40e-1)" "unprognostic (1.10e-2)" "unprognostic (7.65e-2)" "unprognostic (5.52e-3)" "unprognostic (6.36e-2)" "unprognostic (1.27e-1)" "unprognostic (3.90e-2)" "potential prognostic unfavorable (1.89e-4)" "potential prognostic unfavorable (4.10e-4)" "unprognostic (1.66e-1)" "unprognostic (1.00e-1)" "unprognostic (5.57e-2)" "unprognostic (5.31e-2)" "unprognostic (1.15e-1)" "unprognostic (5.30e-2)" "unprognostic (1.38e-1)" "unprognostic (2.25e-1)" "unprognostic (3.35e-1)" ECM2 ENSG00000106823 "Extracellular matrix protein 2" O94769 9 92493554-92536655 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 116.6;ovary: 109.9" "Cell type enhanced" "Detected in many" "Adipocytes: 217.9;Bergmann glia: 110.7;Ependymal cells: 130.5;Epicardial cells: 166.0;Fibro-adipogenic progenitors: 168.9;Fibroblasts: 90.8;Hepatocytes: 91.1;Leydig cells: 225.2;Myosatellite cells: 78.7;Ovarian stromal cells: 91.8;Pericytes: 85.3;Peritubular myoid cells: 110.1;Vascular smooth muscle cells: 80.7" "Group enriched" "Detected in all" 4 "Bergmann glia: 122.4;ependymal cell: 141.9;fibroblast: 242.1;pericyte: 170.0;vascular associated smooth muscle cell: 75.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 2.9" "Adrenal gland - Fibroblasts, Breast - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatocytes, Minor Salivary Gland - Fibroblasts, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035347 Approved Approved "Nucleoli fibrillar center,Endoplasmic reticulum" "Secreted to extracellular matrix" "No annotated function" NA NA 6300000 "Cluster 75: Ovary - Mixed function" "Cluster 46: Brainstem - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 89: Adipocytes - Lipid metabolism" "Nucleoli fibrillar center, Endoplasmic reticulum" "HPA035347: " "unprognostic (4.28e-2)" "unprognostic (3.37e-1)" "unprognostic (9.82e-2)" "unprognostic (4.80e-2)" "unprognostic (1.90e-3)" "unprognostic (1.35e-1)" "unprognostic (7.30e-2)" "unprognostic (1.55e-3)" "unprognostic (1.38e-1)" "unprognostic (3.79e-1)" "validated prognostic favorable (1.63e-4)" "validated prognostic favorable (1.85e-4)" "unprognostic (2.31e-2)" "validated prognostic favorable (9.23e-5)" "validated prognostic favorable (1.02e-7)" "unprognostic (5.06e-3)" "unprognostic (1.33e-1)" "unprognostic (2.38e-2)" "unprognostic (3.51e-2)" "unprognostic (2.39e-3)" "potential prognostic unfavorable (1.81e-4)" "unprognostic (9.53e-2)" "unprognostic (3.56e-2)" "unprognostic (1.32e-1)" "unprognostic (9.67e-2)" "unprognostic (7.18e-3)" "unprognostic (2.05e-2)" "unprognostic (2.88e-3)" "unprognostic (6.66e-2)" "unprognostic (2.38e-2)" "unprognostic (1.21e-1)" ECPAS "ECM29, FLJ22036, KIAA0368" ENSG00000136813 "Ecm29 proteasome adaptor and scaffold" Q5VYK3 9 111360685-111484745 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 227.2" "Cell type enhanced" "Detected in all" "Myonuclei: 505.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Endothelial cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021646, HPA059795" Uncertain Supported Nucleoplasm Yes No 15000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 14: Neurons - Synaptic function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 103: Non-specific - Basic cellular processes" 91 Nucleoplasm "HPA021646: , HPA059795: " "unprognostic (2.84e-1)" "unprognostic (3.73e-2)" "unprognostic (5.71e-2)" "unprognostic (1.58e-1)" "unprognostic (2.58e-3)" "unprognostic (1.63e-1)" "unprognostic (3.20e-2)" "unprognostic (8.27e-2)" "unprognostic (3.53e-1)" "potential prognostic favorable (1.09e-8)" "unprognostic (7.30e-3)" "unprognostic (5.15e-2)" "unprognostic (8.61e-3)" "unprognostic (1.37e-3)" "unprognostic (1.79e-1)" "unprognostic (5.59e-2)" "unprognostic (1.79e-1)" "unprognostic (8.05e-2)" "unprognostic (1.23e-1)" "unprognostic (1.11e-1)" "unprognostic (4.57e-1)" "unprognostic (6.08e-2)" "unprognostic (5.08e-2)" "unprognostic (3.66e-1)" "unprognostic (4.28e-2)" "unprognostic (3.07e-1)" "unprognostic (1.36e-1)" "unprognostic (3.38e-1)" "unprognostic (4.79e-2)" ECRG4 "augurin, C2orf40" ENSG00000119147 "ECRG4 augurin precursor" Q9H1Z8 2 106063246-106078155 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 412.4" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 885.2;Early spermatids: 1213.9;Late primary spermatocytes: 238.8;Late spermatids: 226.9;Pericytes: 418.8;Respiratory ciliated cells: 590.0;Vascular smooth muscle cells: 238.7" "Group enriched" "Detected in many" 4 "choroid plexus epithelial cell: 314.7;ependymal cell: 101.8" "Cancer enriched" "Detected in many" 12 "Thyroid Carcinoma (TCGA): 295.2" "Region enriched" "Detected in all" 10 "choroid plexus: 467.0" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 8.5;naive CD8 T-cell: 7.2" "Lineage enriched" "Detected in single" 83 "T-cells: 8.5" "Not detected" "Not detected" "Liver - Hepatic stellate cells, Spleen - Fibroblasts_1, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008546 Uncertain "Secreted to blood" "No annotated function" NA NA 180000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 110: Mural cells - ECM organization" 2 "HPA008546: " "unprognostic (1.67e-1)" "unprognostic (1.53e-3)" "unprognostic (1.04e-1)" "unprognostic (8.22e-3)" "unprognostic (1.92e-1)" "unprognostic (3.41e-2)" "validated prognostic favorable (5.13e-7)" "validated prognostic favorable (7.90e-5)" "unprognostic (4.07e-2)" "unprognostic (1.21e-3)" "unprognostic (1.24e-1)" "unprognostic (2.18e-1)" "unprognostic (1.52e-1)" "unprognostic (1.48e-1)" "unprognostic (2.82e-1)" "potential prognostic favorable (8.65e-4)" "unprognostic (4.01e-3)" "unprognostic (1.30e-2)" "unprognostic (3.46e-2)" "unprognostic (4.34e-1)" "unprognostic (4.35e-2)" "unprognostic (2.63e-1)" "unprognostic (1.55e-2)" "unprognostic (1.78e-1)" ECSCR "ARIA, ECSM2" ENSG00000249751 "Endothelial cell surface expressed chemotaxis and apoptosis regulator" Q19T08 5 139448560-139462743 "Predicted membrane proteins" "Angiogenesis, Apoptosis, Chemotaxis, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 6 "Lymphatic endothelial cells: 4.8;Vascular endothelial cells: 9.4" "Cell type enriched" "Detected in some" 4 "endothelial cell: 9.7" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 31.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "ovarian cancer: 15.8;pancreatic cancer: 11.4" "Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Lung - Endothelial cells, Minor Salivary Gland - Endothelial cells, Pancreas - Endothelial cells, Pituitary gland - Endothelial cells, Prostate - Endothelial cells, Testis - Endothelial cells, Thyroid gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA063337 Supported "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 1 "Vesicles, Plasma membrane" Nucleoplasm "HPA063337: " "unprognostic (3.62e-1)" "unprognostic (2.93e-1)" "unprognostic (1.39e-1)" "unprognostic (2.83e-2)" "unprognostic (1.33e-2)" "unprognostic (1.18e-1)" "unprognostic (1.30e-1)" "unprognostic (4.55e-2)" "unprognostic (3.36e-2)" "unprognostic (1.89e-1)" "potential prognostic favorable (3.19e-6)" "unprognostic (1.78e-3)" "potential prognostic unfavorable (3.64e-5)" "unprognostic (4.91e-2)" "unprognostic (1.63e-3)" "unprognostic (1.00e-1)" "unprognostic (2.45e-1)" "unprognostic (7.31e-3)" "unprognostic (8.20e-3)" "unprognostic (2.17e-1)" "unprognostic (6.04e-3)" "unprognostic (7.50e-2)" "unprognostic (3.80e-2)" "unprognostic (2.85e-2)" "unprognostic (3.26e-2)" "unprognostic (1.37e-1)" "unprognostic (8.32e-2)" "unprognostic (1.05e-3)" "unprognostic (2.39e-1)" "unprognostic (1.75e-1)" "unprognostic (1.34e-1)" ECSIT SITPEC ENSG00000130159 "ECSIT signaling integrator" Q9BQ95 19 11505929-11529172 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042979 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cellular respiration" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 23: Non-specific - Transcription" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 77 Nucleoplasm Cytosol "HPA042979: " "unprognostic (5.71e-3)" "unprognostic (7.45e-2)" "unprognostic (4.85e-2)" "unprognostic (5.79e-2)" "unprognostic (1.39e-1)" "unprognostic (2.09e-1)" "unprognostic (1.13e-1)" "unprognostic (8.96e-2)" "unprognostic (2.40e-2)" "unprognostic (3.27e-2)" "potential prognostic favorable (6.46e-11)" "unprognostic (1.57e-2)" "unprognostic (8.03e-3)" "unprognostic (2.68e-1)" "unprognostic (5.05e-3)" "unprognostic (1.92e-1)" "unprognostic (2.18e-1)" "unprognostic (2.31e-2)" "unprognostic (1.58e-1)" "unprognostic (1.69e-1)" "unprognostic (7.94e-2)" "unprognostic (2.63e-2)" "unprognostic (3.34e-1)" "unprognostic (2.35e-1)" "unprognostic (2.90e-3)" "unprognostic (1.53e-2)" "unprognostic (9.97e-2)" "unprognostic (5.76e-2)" "unprognostic (1.78e-1)" "unprognostic (2.56e-2)" "unprognostic (1.07e-1)" ECT2 ARHGEF31 ENSG00000114346 "Epithelial cell transforming 2" Q9H8V3 3 172750682-172821474 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Neurogenesis, Protein transport, Transport" "Guanine-nucleotide releasing factor" Oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 134.6;Early primary spermatocytes: 61.0;Erythrocyte progenitors: 65.9;Gastric progenitor cells: 100.0;Monocyte progenitors: 126.4;Neutrophil progenitors: 85.4;Respiratory deuterosomal cells: 61.2" "Cell type enriched" "Detected in all" 4 "endothelial cell: 57.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA036363, HPA053261" Enhanced Nucleoplasm,Cytosol No Yes "Cluster 32: Basophils - Transcription" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 37: Neurons - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 27: Non-specific - Cell proliferation" 67 Nucleoplasm Cytosol "HPA036363: , HPA053261: " "unprognostic (2.00e-2)" "unprognostic (1.02e-1)" "unprognostic (4.81e-2)" "unprognostic (1.23e-1)" "unprognostic (3.18e-2)" "unprognostic (1.30e-1)" "unprognostic (1.50e-1)" "unprognostic (3.64e-2)" "unprognostic (2.06e-2)" "unprognostic (1.72e-3)" "unprognostic (1.17e-3)" "potential prognostic unfavorable (1.88e-6)" "unprognostic (3.32e-2)" "validated prognostic unfavorable (2.93e-6)" "validated prognostic unfavorable (1.66e-6)" "potential prognostic unfavorable (4.55e-7)" "unprognostic (2.77e-3)" "unprognostic (1.38e-2)" "unprognostic (3.85e-2)" "unprognostic (1.02e-1)" "unprognostic (1.45e-2)" "potential prognostic unfavorable (1.34e-5)" "unprognostic (3.33e-2)" "unprognostic (3.60e-2)" "unprognostic (1.25e-1)" "unprognostic (1.05e-1)" "unprognostic (7.28e-2)" "unprognostic (4.09e-3)" "unprognostic (3.05e-1)" "unprognostic (3.33e-2)" "unprognostic (3.05e-1)" ECT2L "ARHGEF32, C6orf91, FBXO49, LFDH" ENSG00000203734 "Epithelial cell transforming 2 like" Q008S8 6 138795911-138904070 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "fallopian tube: 8.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 971.2;Endometrial ciliated cells: 79.4;Ependymal cells: 226.3;Fallopian tube ciliated cells: 226.5;Respiratory ciliated cells: 568.6" "Cell type enriched" "Detected in all" 5 "ependymal cell: 276.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA035488 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 1 Nucleoplasm Vesicles "HPA035488: " "unprognostic (5.68e-2)" EDA "ED1, ED1-A1, ED1-A2, EDA-A1, EDA-A2, EDA1, EDA2, HED, ODT1, XHED, XLHED" ENSG00000158813 "Ectodysplasin A" Q92838 X 69616067-70039472 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Differentiation "Cytokine, Developmental protein" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 298.7;Cardiomyocytes: 265.9;Epicardial cells: 209.2;Fibro-adipogenic progenitors: 400.3;Lacrimal acinar cells: 286.2;Macrophages: 202.8;Mesothelial cells: 200.3" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 220.4;midbrain-derived inhibitory: 210.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.2;MAIT T-cell: 1.3" "Group enriched" "Detected in many" 5 "monocytes: 1.2;T-cells: 1.3" "Cancer enhanced" "Detected in many" "prostate cancer: 6.1" "Adrenal gland - Adrenal cortex cells, Skeletal muscle - Fibroblasts, Stomach - Chief cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA037972, HPA037973" Supported "Vesicles,Lipid droplets" "Secreted - unknown location" Cytokine NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 11: Neuronal - Sensory perception" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 24 Vesicles "Lipid droplets" "HPA037972: , HPA037973: " "unprognostic (1.35e-1)" "unprognostic (3.05e-2)" "unprognostic (1.22e-1)" "unprognostic (4.05e-2)" "unprognostic (5.02e-2)" "unprognostic (3.04e-2)" "unprognostic (1.12e-1)" "unprognostic (5.63e-2)" "unprognostic (1.24e-1)" "validated prognostic favorable (2.26e-7)" "validated prognostic favorable (4.08e-4)" "unprognostic (3.37e-3)" "unprognostic (1.39e-3)" "unprognostic (1.09e-1)" "unprognostic (1.58e-1)" "unprognostic (6.47e-2)" "unprognostic (2.41e-1)" "unprognostic (1.16e-1)" "unprognostic (9.12e-2)" "unprognostic (1.03e-1)" "unprognostic (1.56e-3)" "unprognostic (1.55e-1)" "unprognostic (1.73e-1)" "unprognostic (8.36e-2)" "unprognostic (8.72e-2)" "unprognostic (1.25e-3)" "unprognostic (2.40e-1)" "unprognostic (9.67e-2)" "unprognostic (1.37e-2)" EDA2R "EDA-A2R, EDAA2R, TNFRSF27, XEDAR" ENSG00000131080 "Ectodysplasin A2 receptor" Q9HAV5 X 66595637-66639298 "Predicted membrane proteins" Differentiation "Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 13.9;Medullary thymic epithelial cells: 12.0;Microglia: 20.7;Myonuclei: 10.6;Pituitary stem cells: 9.5;Thymic myoid cells: 32.6" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 29.3;fibroblast: 14.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 18.3;testis cancer: 23.3" "Adipose subcutaneous - Adipose progenitor cells, Skeletal muscle - Fibroblasts, Skin - Endothelial cells" "Not detected" "Not detected" HPA054522 Approved "Cell Junctions" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 30: White matter - Myelination" "Cluster 40: Non-specific - Unknown function" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 14 "Cell Junctions" "HPA054522: " "unprognostic (9.94e-3)" "unprognostic (7.07e-3)" "unprognostic (3.59e-2)" "unprognostic (1.61e-1)" "unprognostic (4.41e-3)" "potential prognostic unfavorable (5.62e-5)" "unprognostic (7.59e-2)" "validated prognostic favorable (1.43e-4)" "validated prognostic favorable (2.26e-4)" "unprognostic (9.19e-3)" "unprognostic (1.96e-3)" "unprognostic (1.04e-2)" "unprognostic (6.41e-2)" "unprognostic (2.54e-2)" "unprognostic (7.83e-2)" "unprognostic (6.30e-3)" "unprognostic (3.57e-1)" "unprognostic (2.95e-1)" "unprognostic (4.28e-1)" "unprognostic (2.36e-1)" "unprognostic (4.36e-2)" EDAR "DL, ED1R, ED3, ED5, EDA1R, EDA3" ENSG00000135960 "Ectodysplasin A receptor" Q9UNE0 2 108894471-108989372 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Apoptosis, Differentiation" "Developmental protein, Receptor" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 3.5" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 10.7;Epicardial cells: 15.9;Esophageal apical cells: 11.9;Esophageal basal cells: 13.4;Esophageal suprabasal cells: 22.0;Prostatic hillock cells: 28.0;Proximal tubule cells: 21.6;Respiratory basal cells: 10.6;Respiratory deuterosomal cells: 9.3;Salivary duct cells: 22.3;Submucosal glandular cells: 16.6;Undifferentiated spermatogonia: 9.1" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in many" "Rectum Adenocarcinoma (TCGA): 8.8" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "naive CD4 T-cell: 7.5;naive CD8 T-cell: 3.8" "Lineage enriched" "Detected in single" 76 "T-cells: 7.5" "Cancer enhanced" "Detected in many" "colorectal cancer: 9.6;Gastric cancer: 9.2;pancreatic cancer: 7.2" "Liver - Hepatocytes, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA042292 Approved NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 9: T-cells - Adaptive immunity: Regulation" "HPA042292: " "unprognostic (1.01e-1)" "unprognostic (6.17e-2)" "unprognostic (1.93e-2)" "unprognostic (7.53e-2)" "unprognostic (2.25e-2)" "potential prognostic favorable (7.35e-4)" "unprognostic (1.86e-1)" "unprognostic (9.54e-2)" "unprognostic (7.16e-2)" "unprognostic (2.07e-1)" "unprognostic (7.15e-2)" "unprognostic (3.42e-1)" "unprognostic (1.28e-2)" "unprognostic (1.98e-1)" EDARADD ENSG00000186197 "EDAR associated death domain" Q8WWZ3 1 236348257-236502915 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Differentiation "Developmental protein" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 8.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 87.2;Epididymal basal cells: 80.4;Mast cells: 139.0;Pancreatic islet cells: 71.9;Papillary tip epithelial cells: 143.4;Renal collecting duct intercalated cells: 125.4;Respiratory basal cells: 100.7;Syncytiotrophoblasts: 62.2;Urothelial cells: 112.3" "Cell type enriched" "Detected in many" 5 "leukocyte: 22.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 8 "basophil: 49.4" "Lineage enriched" "Detected in many" 8 "granulocytes: 49.4" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Minor Salivary Gland - Minor salivary gland basal cells, Stomach - Parietal cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA018836 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 41: Basophils - Unknown function" "Cluster 58: Skin - Keratinization" "Cluster 27: Breast cancer - Unknown function" "Cluster 58: Mast cells - Allergic inflammatory responses" 13 Nucleoplasm Cytosol "HPA018836: " "unprognostic (3.67e-2)" "unprognostic (1.23e-1)" "unprognostic (8.56e-2)" "unprognostic (3.54e-2)" "unprognostic (1.49e-2)" "unprognostic (8.64e-2)" "unprognostic (5.27e-2)" "unprognostic (1.29e-2)" "unprognostic (2.45e-2)" "unprognostic (5.44e-2)" "unprognostic (1.92e-2)" "unprognostic (6.84e-2)" "unprognostic (5.05e-2)" "unprognostic (1.09e-1)" "unprognostic (4.01e-3)" "unprognostic (1.25e-2)" "unprognostic (5.44e-2)" "unprognostic (9.64e-2)" "unprognostic (2.48e-1)" "unprognostic (1.52e-1)" "unprognostic (1.12e-2)" "unprognostic (2.08e-3)" EDC3 "FLJ21128, hYjeF_N2-15q23, LSM16, YJDC, YJEFN2" ENSG00000179151 "Enhancer of mRNA decapping 3" Q96F86 15 74630558-74696292 "Disease related genes, Human disease related genes, Predicted intracellular proteins" RNA-binding "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 149.3;Late spermatids: 308.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040650, HPA044206, HPA066137" Uncertain Supported "Cytoplasmic bodies" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 39: Testis - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 75 "Cytoplasmic bodies" "HPA040650: , HPA044206: , HPA066137: " "unprognostic (3.08e-1)" "unprognostic (1.01e-1)" "unprognostic (3.59e-1)" "unprognostic (3.44e-2)" "unprognostic (1.31e-1)" "unprognostic (3.09e-1)" "unprognostic (2.63e-1)" "unprognostic (1.44e-2)" "unprognostic (1.25e-1)" "unprognostic (5.21e-3)" "potential prognostic favorable (2.59e-4)" "unprognostic (3.90e-3)" "unprognostic (3.93e-1)" "validated prognostic unfavorable (2.27e-6)" "validated prognostic unfavorable (1.24e-5)" "unprognostic (5.77e-2)" "potential prognostic unfavorable (2.62e-5)" "unprognostic (6.79e-2)" "unprognostic (1.16e-2)" "unprognostic (3.83e-2)" "unprognostic (1.90e-1)" "unprognostic (2.96e-1)" "unprognostic (8.14e-3)" "unprognostic (1.44e-1)" "unprognostic (5.92e-2)" "unprognostic (4.80e-2)" "unprognostic (6.19e-2)" "unprognostic (3.06e-2)" "unprognostic (3.52e-1)" "unprognostic (4.89e-2)" "unprognostic (1.33e-1)" EDC4 "Ge-1, HEDLS, RCD-8" ENSG00000038358 "Enhancer of mRNA decapping 4" Q6P2E9 16 67873052-67884499 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 12.3;Bergmann glia: 10.4;Brain excitatory neurons: 15.2;Brain inhibitory neurons: 17.1;Cardiomyocytes: 11.1;Choroid plexus epithelial cells: 8.4;Ependymal cells: 11.0;Epicardial cells: 13.6;Microglia: 9.8;Oligodendrocyte progenitor cells: 13.2;Oligodendrocytes: 14.7;Other brain neurons: 15.7;Tuft cells: 11.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041164, HPA043038" Supported Supported "Nucleoplasm,Cytoplasmic bodies" NA NA 86000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 34: Non-specific - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 22: Non-specific - Basic cellular functions" 46 "Cytoplasmic bodies" Nucleoplasm "HPA041164: , HPA043038: " "unprognostic (3.58e-1)" "unprognostic (3.45e-2)" "unprognostic (1.10e-1)" "unprognostic (1.17e-1)" "unprognostic (3.50e-2)" "unprognostic (7.34e-2)" "unprognostic (1.24e-1)" "potential prognostic favorable (9.00e-4)" "unprognostic (2.08e-1)" "unprognostic (5.48e-2)" "potential prognostic unfavorable (1.15e-4)" "unprognostic (7.21e-2)" "unprognostic (1.02e-2)" "unprognostic (6.81e-3)" "unprognostic (1.42e-1)" "unprognostic (1.02e-1)" "unprognostic (1.61e-2)" "unprognostic (2.29e-1)" "unprognostic (4.81e-2)" "unprognostic (1.88e-1)" "unprognostic (1.29e-1)" "potential prognostic favorable (4.74e-5)" "unprognostic (3.75e-3)" "unprognostic (1.70e-1)" "unprognostic (3.50e-1)" "unprognostic (8.68e-2)" "unprognostic (1.61e-1)" "unprognostic (3.60e-2)" "unprognostic (1.84e-1)" "unprognostic (1.29e-1)" "unprognostic (7.39e-2)" EDDM13 ENSG00000267710 "Epididymal protein 13" A0A1B0GTR0 19 56272748-56310454 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 142 "epididymis: 93.2" "Cell type enriched" "Detected in many" 9 "Epididymal principal cells: 1798.7" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Prostate - Urothelial cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" "unprognostic (1.90e-1)" "unprognostic (2.32e-1)" EDDM3A "FAM12A, HE3-ALPHA" ENSG00000181562 "Epididymal protein 3A" Q14507 14 20745887-20748380 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "epididymis: 600.6" "Cell type enriched" "Detected in some" 87 "Epididymal principal cells: 713.8" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA049952 Approved "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 11: White matter - Signal transduction" "Cluster 50: Lymphoma - Unknown function" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" 7 "HPA049952: " "unprognostic (5.01e-2)" EDDM3B "FAM12B, HE3-BETA" ENSG00000181552 "Epididymal protein 3B" P56851 14 20768404-20770948 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 279 "epididymis: 2419.9" "Cell type enriched" "Detected in some" 88 "Epididymal principal cells: 3064.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA001323 Enhanced "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 50: Lymphoma - Unknown function" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" 17 "HPA001323: " "unprognostic (5.06e-2)" EDEM1 "EDEM, KIAA0212" ENSG00000134109 "ER degradation enhancing alpha-mannosidase like protein 1" Q92611 3 5187646-5219958 "Plasma proteins, Predicted intracellular proteins" "Unfolded protein response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 73.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 134.7;cDC: 166.3;monocytes: 116.7;Neutrophil progenitors: 202.0;Plasma cells: 192.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Spleen - Mitotic cells (Spleen), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029565 Uncertain Enhanced "Endoplasmic reticulum,Aggresome" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 6: Leukemia - Signal transduction" "Cluster 82: Dendritic cells - Antigen presentation" 19 "Endoplasmic reticulum" Aggresome "HPA029565: " "unprognostic (1.60e-1)" "unprognostic (7.96e-2)" "unprognostic (1.01e-1)" "unprognostic (3.67e-2)" "unprognostic (8.85e-2)" "unprognostic (1.55e-1)" "unprognostic (3.09e-1)" "unprognostic (1.27e-1)" "unprognostic (2.09e-2)" "unprognostic (2.63e-2)" "unprognostic (6.57e-2)" "unprognostic (6.27e-2)" "unprognostic (2.22e-1)" "unprognostic (1.61e-1)" "unprognostic (6.38e-2)" "unprognostic (1.52e-2)" "unprognostic (1.45e-1)" "unprognostic (1.42e-3)" "unprognostic (2.12e-1)" "unprognostic (3.89e-3)" "unprognostic (1.24e-1)" "unprognostic (1.64e-3)" "unprognostic (8.42e-3)" "unprognostic (2.26e-1)" "unprognostic (7.17e-2)" "unprognostic (5.28e-3)" "unprognostic (4.24e-2)" "unprognostic (2.90e-1)" "unprognostic (3.54e-2)" "unprognostic (1.29e-1)" "unprognostic (1.33e-1)" EDEM2 "bA4204.1, C20orf31, C20orf49, FLJ10783" ENSG00000088298 "ER degradation enhancing alpha-mannosidase like protein 2" Q9BV94 20 35115364-35147336 "Predicted intracellular proteins" "Unfolded protein response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 212.4;Plasma cells: 95.1;Syncytiotrophoblasts: 116.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Macrophages, Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037238, HPA048353" Approved "Intracellular and membrane" Other NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 70: Non-specific - Protein processing" "Cluster 25: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 8: Non-specific - Secretory pathway" 1 "CAB037238: , HPA048353: " "unprognostic (4.08e-2)" "unprognostic (5.56e-2)" "unprognostic (6.17e-2)" "unprognostic (5.34e-2)" "unprognostic (2.59e-1)" "unprognostic (9.01e-2)" "unprognostic (1.48e-2)" "unprognostic (2.64e-3)" "unprognostic (1.06e-1)" "unprognostic (3.20e-2)" "unprognostic (3.38e-3)" "potential prognostic unfavorable (2.19e-5)" "unprognostic (3.12e-1)" "potential prognostic unfavorable (6.73e-5)" "unprognostic (5.68e-3)" "unprognostic (2.76e-1)" "unprognostic (3.54e-2)" "unprognostic (3.08e-1)" "unprognostic (1.47e-1)" "unprognostic (1.89e-1)" "unprognostic (3.76e-2)" "unprognostic (5.41e-2)" "unprognostic (9.01e-2)" "unprognostic (2.18e-1)" "unprognostic (7.65e-3)" "unprognostic (2.77e-3)" "unprognostic (1.92e-1)" "unprognostic (1.78e-1)" "unprognostic (4.23e-2)" "unprognostic (3.14e-1)" "unprognostic (2.57e-1)" EDEM3 C1orf22 ENSG00000116406 "ER degradation enhancing alpha-mannosidase like protein 3" Q9BZQ6 1 184690237-184754907 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Unfolded protein response" Hydrolase "Congenital disorder of glycosylation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Lactotrophs: 246.4;Neutrophil progenitors: 506.1;Thyrotrophs: 261.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Myeloma: 76.1" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025754, HPA025755, HPA027297" Approved Approved "Endoplasmic reticulum" "Intracellular and membrane" Enzyme NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 77: Intestine - Digestion" "Cluster 21: Non-specific - Metabolism" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 35 "Endoplasmic reticulum" "HPA025754: , HPA025755: , HPA027297: " "unprognostic (2.66e-1)" "unprognostic (1.22e-1)" "unprognostic (1.57e-1)" "unprognostic (4.02e-3)" "unprognostic (2.00e-2)" "unprognostic (1.74e-1)" "unprognostic (1.70e-1)" "unprognostic (8.34e-2)" "unprognostic (1.39e-1)" "unprognostic (4.73e-3)" "potential prognostic favorable (5.78e-4)" "unprognostic (3.10e-2)" "unprognostic (1.19e-2)" "unprognostic (2.28e-1)" "unprognostic (1.82e-1)" "unprognostic (7.66e-2)" "unprognostic (2.25e-2)" "unprognostic (1.88e-2)" "unprognostic (1.26e-1)" "unprognostic (1.48e-1)" "unprognostic (5.65e-3)" "unprognostic (4.04e-2)" "unprognostic (3.43e-3)" "unprognostic (1.01e-1)" "unprognostic (6.55e-2)" "potential prognostic unfavorable (1.10e-5)" "unprognostic (7.84e-2)" "unprognostic (2.03e-1)" "unprognostic (1.31e-1)" "unprognostic (9.08e-3)" "unprognostic (7.91e-2)" EDF1 "CFAP280, EDF-1" ENSG00000107223 "Endothelial differentiation related factor 1" O60869 9 136862119-136866308 "Predicted intracellular proteins" "Differentiation, Transcription, Transcription regulation" "Activator, Calmodulin-binding, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 2429.1;Esophageal apical cells: 2970.1;Esophageal suprabasal cells: 1512.5;Syncytiotrophoblasts: 1387.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035642 Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA 9300 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 70: Non-specific - Protein processing" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 22 Cytosol "Nucleoplasm, Nucleoli" "HPA035642: " "unprognostic (8.23e-2)" "unprognostic (2.66e-1)" "unprognostic (7.83e-2)" "unprognostic (5.81e-3)" "unprognostic (7.90e-2)" "unprognostic (1.40e-3)" "unprognostic (4.38e-3)" "unprognostic (7.55e-2)" "unprognostic (3.35e-2)" "unprognostic (3.19e-1)" "unprognostic (6.96e-2)" "unprognostic (3.03e-2)" "unprognostic (4.44e-2)" "unprognostic (5.30e-3)" "unprognostic (3.55e-2)" "unprognostic (2.35e-2)" "unprognostic (1.54e-1)" "unprognostic (7.15e-2)" "unprognostic (1.19e-1)" "unprognostic (2.05e-1)" "unprognostic (9.46e-2)" "unprognostic (2.19e-3)" "unprognostic (2.14e-1)" "unprognostic (1.45e-1)" "unprognostic (5.65e-2)" "unprognostic (4.18e-3)" "unprognostic (2.76e-2)" "unprognostic (5.46e-2)" "unprognostic (3.08e-2)" "unprognostic (3.24e-1)" "unprognostic (5.77e-2)" EDIL3 DEL1 ENSG00000164176 "EGF like repeats and discoidin domains 3" O43854 5 83940554-84384880 "Predicted secreted proteins" "Cell adhesion" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 82.2;brain: 174.8" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 475.9;Oligodendrocyte progenitor cells: 765.7;Oligodendrocytes: 2348.9;Other brain neurons: 260.2;Pancreatic islet cells: 322.7;Retinal amacrine cells: 422.9;Retinal bipolar cells: 1093.5;Retinal ganglion cells: 301.3;Salivary duct cells: 266.4;Vascular smooth muscle cells: 306.7" "Cell type enhanced" "Detected in all" "hippocampal dentate gyrus: 2255.3;oligodendrocyte: 3119.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 114.3;Kidney cancer: 115.5" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Prostate - Fibroblasts, Skin - Outer root sheath cells, Spleen - Smooth muscle cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020415, HPA022122" Approved Uncertain "Plasma membrane" "Secreted to blood" "Developmental protein" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "Plasma membrane" "HPA020415: , HPA022122: " "unprognostic (3.11e-2)" "unprognostic (5.14e-2)" "unprognostic (2.92e-1)" "unprognostic (2.28e-1)" "unprognostic (9.77e-2)" "unprognostic (3.36e-1)" "unprognostic (1.67e-1)" "unprognostic (1.41e-1)" "unprognostic (9.89e-2)" "unprognostic (2.98e-1)" "unprognostic (7.52e-3)" "unprognostic (2.13e-2)" "unprognostic (3.68e-2)" "unprognostic (2.41e-2)" "unprognostic (1.23e-1)" "unprognostic (7.06e-2)" "unprognostic (5.94e-2)" "unprognostic (1.76e-1)" "unprognostic (1.72e-1)" "unprognostic (1.98e-1)" "potential prognostic unfavorable (4.78e-4)" "unprognostic (1.68e-1)" "unprognostic (1.73e-1)" "unprognostic (8.74e-2)" "unprognostic (2.00e-1)" "unprognostic (1.11e-1)" "unprognostic (2.03e-2)" "unprognostic (2.52e-2)" "unprognostic (1.93e-1)" "unprognostic (4.54e-3)" "unprognostic (9.47e-3)" EDN1 ET1 ENSG00000078401 "Endothelin 1" P05305 6 12290361-12297194 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Vasoactive, Vasoconstrictor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 41.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 226.1;Basal keratinocytes: 170.8;Breast secretory cells: 252.1;Colonocytes: 167.4;Endometrial ciliated cells: 173.4;Endometrial glandular cells: 279.9;Endometrial luminal cells: 242.6;Endometrial secretory cells: 224.3;Enteric stem cells: 294.4;Enteric transient amplifying cells: 170.1;Enterocytes: 141.9;Epididymal basal cells: 356.3;Epididymal efferent duct absorptive cells: 211.6;Pancreatic duct cells: 256.3;Vascular endothelial cells: 182.0" "Cell type enriched" "Detected in many" 24 "endothelial cell: 140.5" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 51.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "non-classical monocyte: 4.9" "Lineage enriched" "Detected in single" 6 "monocytes: 4.9" "Cancer enhanced" "Detected in many" "testis cancer: 108.1" "Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA031976, HPA031978, CAB032500, CAB037291" Approved Approved "Golgi apparatus" "Secreted to blood" Other NA Yes 9740 "Cluster 25: Non-specific - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "Golgi apparatus" "CAB032500: , CAB037291: , HPA031976: , HPA031978: " "unprognostic (2.12e-1)" "unprognostic (1.41e-2)" "unprognostic (2.30e-1)" "unprognostic (1.60e-1)" "unprognostic (1.12e-1)" "unprognostic (6.91e-3)" "unprognostic (3.35e-1)" "unprognostic (1.20e-1)" "unprognostic (1.42e-1)" "unprognostic (9.57e-3)" "validated prognostic favorable (1.94e-5)" "validated prognostic favorable (1.95e-5)" "unprognostic (1.65e-1)" "unprognostic (4.91e-2)" "unprognostic (7.88e-3)" "unprognostic (3.91e-1)" "unprognostic (2.86e-1)" "unprognostic (1.62e-3)" "unprognostic (4.40e-2)" "unprognostic (2.26e-2)" "unprognostic (1.15e-2)" "unprognostic (1.80e-2)" "unprognostic (1.43e-1)" "unprognostic (3.27e-1)" "unprognostic (1.31e-2)" "unprognostic (4.43e-3)" "unprognostic (1.13e-1)" "unprognostic (1.15e-1)" "unprognostic (1.54e-1)" "unprognostic (8.11e-2)" "unprognostic (1.22e-1)" EDN2 ET2 ENSG00000127129 "Endothelin 2" P20800 1 41478775-41484683 "Predicted secreted proteins" "Vasoactive, Vasoconstrictor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 29.8;esophagus: 20.2;vagina: 31.7" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 85.4;Conjunctival goblet cells: 421.4;Enterocytes: 93.6;Esophageal apical cells: 376.7;Prostatic club cells: 175.4;Prostatic hillock cells: 152.9;Salivary duct cells: 56.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 47.7" "Region enriched" "Detected in single" 7 "choroid plexus: 2.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 30.6;Uterine cancer: 24.8" "Adipose visceral - Mesothelial cells, Minor Salivary Gland - Minor salivary gland basal cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA028459 Uncertain Approved Cytosol "Secreted to blood" Other NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 36: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 84: Apical squamous epithelium - Cornification" Cytosol "HPA028459: " "unprognostic (2.77e-1)" "unprognostic (1.02e-1)" "unprognostic (2.25e-1)" "unprognostic (6.92e-2)" "unprognostic (2.02e-2)" "unprognostic (1.82e-1)" "potential prognostic favorable (2.81e-5)" "unprognostic (1.19e-3)" "unprognostic (1.26e-3)" "unprognostic (9.04e-2)" "unprognostic (8.24e-3)" "unprognostic (2.97e-2)" "unprognostic (1.44e-1)" "unprognostic (3.92e-2)" "unprognostic (8.40e-2)" "potential prognostic unfavorable (4.74e-4)" "unprognostic (2.71e-3)" "unprognostic (1.37e-2)" "unprognostic (5.48e-2)" "unprognostic (3.61e-2)" "unprognostic (5.42e-2)" EDN3 ET3 ENSG00000124205 "Endothelin 3" P14138 20 59300443-59325992 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Vasoactive, Vasoconstrictor" "Deafness, Disease variant, Hirschsprung disease, Waardenburg syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 47.1;pituitary gland: 45.8;salivary gland: 64.3;vagina: 102.4" "Cell type enriched" "Detected in some" 6 "Pituicytes/FSCs: 722.6" "Group enriched" "Detected in some" 11 "endothelial cell: 95.4;fibroblast: 146.8" "Cancer enhanced" "Detected in many" "Pancreatic Adenocarcinoma (TCGA): 17.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 19.1;Uterine cancer: 25.7" "Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" Other NA NA 30900 "Cluster 11: Esophagus - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 52 "unprognostic (9.03e-3)" "unprognostic (9.80e-2)" "unprognostic (1.83e-1)" "unprognostic (4.41e-2)" "unprognostic (3.00e-1)" "potential prognostic favorable (1.16e-4)" "unprognostic (1.15e-1)" "unprognostic (5.84e-2)" "unprognostic (1.79e-1)" "unprognostic (2.30e-1)" "unprognostic (1.48e-2)" "unprognostic (8.71e-2)" "unprognostic (1.51e-2)" "unprognostic (2.07e-1)" "unprognostic (2.08e-1)" "unprognostic (1.73e-1)" "unprognostic (4.41e-2)" "unprognostic (1.23e-1)" "unprognostic (1.98e-2)" "unprognostic (2.00e-3)" EDNRA "ET-A, ETA-R, hET-AR" ENSG00000151617 "Endothelin receptor type A" P25101 4 147480917-147544954 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 107.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 83.6;Decidual stromal cells: 133.8;Endometrial stromal cells: 191.7;Leydig cells: 127.0;Ovarian stromal cells: 112.2;Pericytes: 260.6;Peritubular myoid cells: 161.1;Respiratory ionocytes: 55.9;Smooth muscle cells: 81.2;Vascular smooth muscle cells: 302.2" "Group enriched" "Detected in many" 24 "pericyte: 307.5;vascular associated smooth muscle cell: 339.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Liver - Hepatic stellate cells, Minor Salivary Gland - Fibroblasts, Prostate - Smooth muscle cells, Spleen - Fibroblasts_1, Testis - Peritubular cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013774, CAB018957" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 110: Mural cells - ECM organization" 27 "Plasma membrane, Cytosol" "CAB018957: , HPA013774: " "unprognostic (1.06e-1)" "unprognostic (8.17e-2)" "unprognostic (3.08e-2)" "unprognostic (5.06e-2)" "unprognostic (1.01e-1)" "unprognostic (4.26e-2)" "unprognostic (9.72e-2)" "potential prognostic favorable (1.72e-4)" "unprognostic (4.08e-1)" "unprognostic (7.02e-2)" "unprognostic (4.67e-3)" "potential prognostic favorable (9.23e-4)" "potential prognostic unfavorable (4.71e-5)" "unprognostic (5.16e-2)" "unprognostic (2.76e-1)" "unprognostic (2.27e-1)" "unprognostic (1.79e-3)" "unprognostic (2.34e-2)" "unprognostic (1.62e-1)" "unprognostic (2.98e-3)" "potential prognostic unfavorable (1.36e-5)" "unprognostic (8.61e-3)" "unprognostic (1.43e-1)" "unprognostic (2.19e-1)" "unprognostic (2.53e-1)" "unprognostic (3.86e-2)" "unprognostic (4.74e-3)" "unprognostic (2.35e-3)" "unprognostic (1.32e-2)" "unprognostic (1.80e-2)" "unprognostic (1.97e-2)" EDNRB "ETB, HSCR, HSCR2" ENSG00000136160 "Endothelin receptor type B" P24530 13 77895481-77975529 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Albinism, Deafness, Disease variant, FDA approved drug targets, Hirschsprung disease, Waardenburg syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 120.1" "Cell type enhanced" "Detected in many" "Astrocytes: 304.8;Bergmann glia: 185.5;Fibroblasts: 111.2;Hepatic stellate cells: 174.3;Lymphatic endothelial cells: 193.0;Melanocytes: 750.2;Müller glia: 136.6;Pericytes: 261.6;Pituicytes/FSCs: 91.5;Schwann cells: 104.1;Vascular endothelial cells: 98.0" "Group enriched" "Detected in many" 4 "astrocyte: 449.1;Bergmann glia: 203.3" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 284.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 12 "Myeloma: 84.2;skin cancer: 130.7" "Adrenal gland - Fibroblasts, Liver - Hepatic stellate cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017842, HPA027546" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 17: Non-specific - RNA processing" 1 "Plasma membrane" Cytosol "CAB017842: , HPA027546: " "unprognostic (2.40e-1)" "unprognostic (1.63e-1)" "unprognostic (1.29e-2)" "unprognostic (2.14e-1)" "unprognostic (1.03e-2)" "unprognostic (1.26e-1)" "unprognostic (2.97e-2)" "unprognostic (5.30e-2)" "unprognostic (1.58e-2)" "unprognostic (1.66e-1)" "validated prognostic favorable (7.14e-12)" "validated prognostic favorable (1.07e-4)" "unprognostic (1.35e-3)" "unprognostic (3.71e-3)" "unprognostic (3.39e-3)" "unprognostic (2.64e-1)" "unprognostic (1.57e-2)" "potential prognostic unfavorable (7.94e-4)" "unprognostic (1.01e-1)" "unprognostic (6.55e-2)" "unprognostic (7.17e-2)" "unprognostic (1.32e-1)" "unprognostic (4.97e-2)" "unprognostic (4.04e-2)" "unprognostic (1.70e-1)" "unprognostic (9.80e-2)" "unprognostic (7.73e-2)" "unprognostic (3.67e-3)" "unprognostic (8.02e-2)" "unprognostic (4.03e-2)" "unprognostic (1.84e-1)" EDRF1 "C10orf137, DKFZp586F1019, FLJ21617" ENSG00000107938 "Erythroid differentiation regulatory factor 1" Q3B7T1 10 125719515-125764143 "Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 256.9;Sertoli cells: 175.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031820 Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 18 Nucleoplasm "Centrosome, Cytosol" "HPA031820: " "unprognostic (1.89e-2)" "unprognostic (2.31e-3)" "unprognostic (3.55e-1)" "unprognostic (1.72e-1)" "unprognostic (1.09e-2)" "unprognostic (1.80e-1)" "potential prognostic favorable (2.54e-4)" "unprognostic (4.27e-3)" "unprognostic (4.50e-2)" "unprognostic (1.49e-2)" "unprognostic (2.00e-1)" "unprognostic (2.88e-1)" "unprognostic (2.30e-2)" "unprognostic (1.13e-1)" "unprognostic (3.06e-1)" "unprognostic (5.25e-2)" "unprognostic (4.93e-2)" "unprognostic (2.94e-1)" "unprognostic (2.43e-1)" "unprognostic (9.34e-3)" "unprognostic (2.79e-3)" "unprognostic (5.73e-2)" "unprognostic (1.02e-2)" "unprognostic (1.45e-1)" "unprognostic (3.50e-1)" "unprognostic (1.29e-1)" "unprognostic (1.72e-1)" "unprognostic (4.69e-2)" "unprognostic (3.84e-2)" EEA1 ZFYVE2 ENSG00000102189 "Early endosome antigen 1" Q15075 12 92770637-92929331 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005861, CAB018782, HPA038158, HPA038159" Supported Supported Vesicles NA NA 47000 "Cluster 63: Non-specific - Basic cellular processes" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 100: Stratified epithelial cells - Barrier functions" 33 Vesicles "CAB005861: , CAB018782: , HPA038158: , HPA038159: " "unprognostic (5.92e-3)" "unprognostic (1.19e-1)" "unprognostic (7.96e-2)" "unprognostic (1.83e-1)" "unprognostic (1.43e-1)" "unprognostic (2.47e-2)" "unprognostic (1.75e-1)" "unprognostic (5.99e-2)" "unprognostic (1.07e-2)" "potential prognostic unfavorable (1.01e-4)" "unprognostic (2.28e-3)" "unprognostic (9.00e-2)" "unprognostic (1.95e-1)" "unprognostic (3.18e-2)" "unprognostic (8.34e-3)" "unprognostic (4.52e-2)" "unprognostic (4.91e-2)" "unprognostic (2.03e-3)" "unprognostic (1.01e-1)" "unprognostic (1.74e-1)" "unprognostic (1.26e-3)" "unprognostic (1.31e-1)" "unprognostic (2.23e-2)" "unprognostic (1.34e-1)" "unprognostic (1.90e-2)" "unprognostic (3.33e-1)" "unprognostic (2.53e-1)" "unprognostic (8.89e-2)" "unprognostic (2.92e-1)" "unprognostic (2.69e-2)" "unprognostic (1.88e-1)" EED "HEED, WAIT-1" ENSG00000074266 "Embryonic ectoderm development" O75530 11 86201212-86278813 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012211, HPA046731, HPA061140" Supported Supported Nucleoplasm,Cytosol NA Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 49: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 9: T-cells - Adaptive immunity: Regulation" 96 Nucleoplasm Cytosol "CAB012211: , HPA046731: , HPA061140: " "unprognostic (3.06e-2)" "unprognostic (4.52e-2)" "unprognostic (1.79e-2)" "unprognostic (1.31e-1)" "unprognostic (2.77e-1)" "unprognostic (1.87e-2)" "unprognostic (8.72e-2)" "unprognostic (3.66e-2)" "unprognostic (1.29e-1)" "unprognostic (4.70e-3)" "unprognostic (3.98e-2)" "unprognostic (4.00e-1)" "unprognostic (3.50e-1)" "potential prognostic unfavorable (8.16e-6)" "unprognostic (5.62e-2)" "unprognostic (1.22e-2)" "unprognostic (2.99e-3)" "unprognostic (1.66e-1)" "unprognostic (2.04e-1)" "unprognostic (2.36e-1)" "unprognostic (4.00e-1)" "unprognostic (1.76e-1)" "unprognostic (1.36e-3)" "unprognostic (1.06e-3)" "unprognostic (5.46e-2)" "unprognostic (1.03e-1)" "unprognostic (9.84e-3)" "unprognostic (4.94e-2)" "unprognostic (4.88e-2)" "unprognostic (4.41e-2)" "unprognostic (1.08e-1)" EEF1A1 "EE1A1, EEF1A, EF1A, EF1A1, EF1alpha1, LENG7" ENSG00000156508 "Eukaryotic translation elongation factor 1 alpha 1" P68104 6 73489308-73525587 "Cancer-related genes, Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis, Transcription, Transcription regulation" "Elongation factor, Hydrolase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enteric stem cells: 5147.5;Enteric transient amplifying cells: 3989.8;Epididymal basal cells: 3857.6;Epididymal efferent duct absorptive cells: 4827.8;Epididymal principal cells: 3303.8;Paneth cells: 4010.5" "Cell type enhanced" "Detected in all" "leukocyte: 147.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA051759, HPA053862, HPA056990" Supported Supported Cytosol NA NA 76000000 "Cluster 33: Non-specific - ATP binding" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 158 Cytosol "HPA051759: , HPA053862: , HPA056990: " "unprognostic (1.27e-2)" "unprognostic (1.40e-1)" "unprognostic (1.79e-1)" "unprognostic (1.77e-2)" "unprognostic (8.02e-2)" "unprognostic (7.54e-3)" "unprognostic (1.71e-2)" "unprognostic (9.77e-2)" "unprognostic (5.07e-2)" "unprognostic (2.66e-1)" "validated prognostic favorable (5.22e-5)" "validated prognostic favorable (6.73e-4)" "unprognostic (7.90e-2)" "potential prognostic unfavorable (1.24e-6)" "unprognostic (6.25e-3)" "unprognostic (3.97e-2)" "unprognostic (1.32e-1)" "unprognostic (1.45e-1)" "unprognostic (7.02e-2)" "unprognostic (1.16e-1)" "unprognostic (5.60e-3)" "unprognostic (2.08e-1)" "unprognostic (6.81e-2)" "unprognostic (2.04e-1)" "unprognostic (1.11e-2)" "unprognostic (1.20e-1)" "unprognostic (1.36e-1)" "unprognostic (9.60e-2)" "unprognostic (4.38e-1)" "unprognostic (4.33e-1)" "unprognostic (6.98e-2)" EEF1A2 "EEF1AL, HS1, STN, STNL" ENSG00000101210 "Eukaryotic translation elongation factor 1 alpha 2" Q05639 20 63488013-63499239 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Elongation factor, Hydrolase" "Autism spectrum disorder, Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 722.2;skeletal muscle: 1827.0" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 113.4;Brain inhibitory neurons: 77.9;Corticotrophs: 84.1;Gonadotrophs: 74.4;Myonuclei: 71.1;Other brain neurons: 133.8;Pancreatic islet cells: 167.5;Retinal amacrine cells: 60.1;Retinal bipolar cells: 83.7;Retinal horizontal cells: 154.3;Thymic myoid cells: 613.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034019, HPA051759, HPA053862, HPA056990" Approved Approved Cytosol NA NA 44000000 "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 60 Cytosol "CAB034019: , HPA051759: , HPA053862: , HPA056990: " "unprognostic (7.36e-2)" "unprognostic (2.95e-2)" "unprognostic (3.43e-1)" "unprognostic (9.03e-2)" "potential prognostic unfavorable (9.06e-4)" "unprognostic (1.94e-2)" "unprognostic (4.71e-3)" "unprognostic (2.06e-1)" "unprognostic (5.90e-3)" "unprognostic (1.86e-2)" "unprognostic (5.67e-3)" "unprognostic (1.18e-1)" "unprognostic (2.41e-1)" "unprognostic (4.89e-1)" "unprognostic (1.95e-2)" "unprognostic (2.37e-1)" "unprognostic (4.03e-2)" "unprognostic (1.52e-1)" "unprognostic (1.41e-1)" "unprognostic (1.03e-2)" "unprognostic (7.52e-3)" "unprognostic (1.11e-2)" "unprognostic (1.66e-3)" "unprognostic (3.07e-1)" "unprognostic (4.09e-2)" "unprognostic (1.58e-2)" "unprognostic (1.79e-2)" "unprognostic (3.49e-3)" "unprognostic (1.52e-1)" "unprognostic (9.06e-3)" "potential prognostic unfavorable (2.26e-4)" EEF1AKMT1 N6AMT2 ENSG00000150456 "EEF1A lysine methyltransferase 1" Q8WVE0 13 20728731-20773961 "Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 95.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040417, HPA042543" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 76: Non-specific - Metabolism" "Cluster 31: Non-specific - Transcription" "Cluster 19: Non-specific - Unknown function" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 2 "Plasma membrane, Cytosol" "HPA040417: , HPA042543: " "unprognostic (2.74e-1)" "unprognostic (1.60e-1)" "unprognostic (1.34e-2)" "unprognostic (3.88e-1)" "unprognostic (2.61e-1)" "unprognostic (3.29e-2)" "potential prognostic unfavorable (1.37e-4)" "unprognostic (1.37e-1)" "unprognostic (1.80e-3)" "potential prognostic favorable (2.17e-4)" "unprognostic (8.17e-2)" "potential prognostic favorable (3.24e-4)" "unprognostic (2.94e-1)" "unprognostic (5.80e-2)" "unprognostic (1.49e-2)" "unprognostic (4.59e-2)" "unprognostic (2.81e-3)" "unprognostic (1.76e-1)" "unprognostic (4.33e-2)" "unprognostic (2.01e-2)" "unprognostic (2.10e-1)" "unprognostic (3.75e-2)" "unprognostic (1.42e-1)" "unprognostic (1.54e-2)" "unprognostic (3.30e-2)" "unprognostic (2.67e-1)" "unprognostic (1.60e-1)" "unprognostic (5.88e-2)" "unprognostic (7.17e-3)" EEF1AKMT2 "C10orf138, Efm4, METTL10" ENSG00000203791 "EEF1A lysine methyltransferase 2" Q5JPI9 10 124748149-124791887 "Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 12.6;Late primary spermatocytes: 35.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050138 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 1: T-cells - Unknown function" "Cluster 65: Brain - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 1 "Nucleoplasm, Cytosol" "HPA050138: " "unprognostic (4.18e-2)" "unprognostic (2.50e-1)" "unprognostic (4.88e-3)" "unprognostic (4.34e-2)" "unprognostic (7.68e-2)" "unprognostic (1.32e-1)" "unprognostic (6.64e-3)" "unprognostic (3.40e-1)" "unprognostic (7.17e-2)" "potential prognostic favorable (5.38e-5)" "unprognostic (3.14e-2)" "unprognostic (3.32e-1)" "unprognostic (8.13e-3)" "unprognostic (2.23e-3)" "unprognostic (5.67e-2)" "unprognostic (2.16e-3)" "unprognostic (1.15e-3)" "unprognostic (3.30e-1)" "unprognostic (2.93e-2)" "unprognostic (5.23e-1)" "unprognostic (1.21e-2)" "unprognostic (1.53e-3)" "unprognostic (1.01e-1)" "unprognostic (3.47e-2)" "unprognostic (2.18e-2)" "unprognostic (3.50e-1)" "unprognostic (4.13e-1)" "potential prognostic unfavorable (9.02e-5)" "unprognostic (2.20e-1)" EEF1AKMT3 "DKFZP586D0919, FAM119B, METTL21B" ENSG00000123427 "EEF1A lysine methyltransferase 3" Q96AZ1 12 57771492-57782541 "Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 6.2;Early spermatids: 12.0;Epicardial cells: 27.3;Late spermatids: 23.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Stomach - Chief cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA043020, HPA045492" Uncertain Approved "Nucleoplasm,Mitotic chromosome,Centrosome" Yes NA "Cluster 33: Non-specific - ATP binding" "Cluster 60: Stomach - Digestion" "Cluster 6: Non-specific - Immune response" "Cluster 38: Non-specific - Transcription" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 176 Centrosome "Nucleoplasm, Mitotic chromosome" "HPA043020: , HPA045492: " "unprognostic (1.21e-2)" "unprognostic (1.34e-1)" "unprognostic (3.39e-2)" "unprognostic (1.04e-1)" "unprognostic (2.63e-1)" "unprognostic (3.73e-1)" "unprognostic (1.07e-1)" "unprognostic (1.84e-1)" "unprognostic (1.27e-3)" "unprognostic (1.56e-3)" "unprognostic (1.47e-2)" "unprognostic (1.61e-1)" "unprognostic (3.30e-3)" "unprognostic (9.25e-2)" "unprognostic (5.25e-3)" "unprognostic (1.20e-1)" "unprognostic (6.64e-2)" "unprognostic (3.61e-2)" "unprognostic (8.95e-2)" "unprognostic (2.18e-1)" "unprognostic (6.78e-2)" "unprognostic (2.78e-1)" "unprognostic (1.92e-2)" "unprognostic (3.48e-2)" "unprognostic (9.51e-3)" "unprognostic (1.32e-1)" "unprognostic (6.34e-2)" "unprognostic (9.99e-3)" "unprognostic (1.90e-1)" EEF1AKMT4 ENSG00000284753 "EEF1A lysine methyltransferase 4" P0DPD7 3 184249672-184258759 "Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 3.5;Brain excitatory neurons: 2.4;Brain inhibitory neurons: 2.3;Choroid plexus epithelial cells: 2.3;Early spermatids: 2.6;Late primary spermatocytes: 4.7;Late spermatids: 4.5;Melanocytes: 2.0;Microglia: 2.0;Mucous neck cells: 2.0;Other brain neurons: 4.0;Parietal cells: 1.8;Suprabasal keratinocytes: 5.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Macrophages, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA062215 Uncertain Nucleoplasm,Cytosol NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 21: Testis - Mixed function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 63: Non-specific - Protein processing" "Cluster 98: Neurons - Neurotransmission & signaling" "Nucleoplasm, Cytosol" "HPA062215: " "unprognostic (6.42e-3)" "unprognostic (4.72e-3)" "unprognostic (5.99e-2)" "unprognostic (5.23e-2)" "unprognostic (9.12e-3)" "unprognostic (2.88e-1)" "unprognostic (4.71e-2)" "unprognostic (7.42e-3)" "validated prognostic unfavorable (1.89e-4)" "validated prognostic unfavorable (5.94e-5)" "potential prognostic unfavorable (2.00e-6)" "potential prognostic unfavorable (1.47e-4)" "potential prognostic unfavorable (2.71e-4)" "unprognostic (7.08e-3)" "unprognostic (9.72e-3)" "unprognostic (1.48e-3)" "unprognostic (6.34e-3)" "unprognostic (7.31e-3)" "unprognostic (1.76e-2)" "unprognostic (2.79e-1)" "unprognostic (3.32e-1)" "unprognostic (1.90e-1)" "unprognostic (2.74e-2)" "unprognostic (3.42e-1)" "unprognostic (1.23e-1)" "unprognostic (1.39e-1)" EEF1AKMT4-ECE2 ENSG00000284917 "EEF1AKMT4-ECE2 readthrough" P0DPD8 3 184249695-184293031 "Enzymes, Predicted membrane proteins" "Hydrolase, Metalloprotease, Methyltransferase, Multifunctional enzyme, Protease, Transferase" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Early spermatids: 19.5;Late spermatids: 51.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA062215 Uncertain Nucleoplasm,Cytosol NA NA "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" "Nucleoplasm, Cytosol" "HPA062215: " EEF1B2 ENSG00000114942 "Eukaryotic translation elongation factor 1 beta 2" P24534 2 206159585-206162928 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Elongation factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 2359.3;Esophageal suprabasal cells: 3042.7;Pancreatic acinar cells: 2272.4" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 204.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012477, HPA035029" Supported Approved "Nucleoli fibrillar center,Cytosol" NA NA 940000 "Cluster 24: Non-specific - Transcription" "Cluster 24: Non-specific - Transcription" "Cluster 36: Choroid plexus - Mixed function" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 27 "Nucleoli fibrillar center, Cytosol" "CAB012477: , HPA035029: " "unprognostic (1.29e-2)" "unprognostic (2.76e-3)" "unprognostic (7.37e-2)" "unprognostic (2.16e-2)" "unprognostic (2.87e-1)" "unprognostic (6.08e-2)" "unprognostic (1.01e-1)" "unprognostic (4.06e-2)" "unprognostic (1.72e-1)" "unprognostic (6.28e-2)" "unprognostic (2.38e-3)" "unprognostic (2.08e-1)" "unprognostic (1.66e-3)" "validated prognostic unfavorable (1.11e-4)" "validated prognostic unfavorable (1.29e-5)" "unprognostic (5.86e-2)" "unprognostic (2.55e-3)" "unprognostic (2.36e-1)" "unprognostic (1.37e-2)" "unprognostic (2.14e-1)" "unprognostic (3.06e-1)" "unprognostic (5.16e-3)" "unprognostic (3.40e-1)" "unprognostic (1.15e-1)" "unprognostic (1.79e-2)" "unprognostic (9.18e-2)" "unprognostic (1.65e-1)" "unprognostic (3.88e-1)" "unprognostic (4.00e-1)" "unprognostic (3.61e-1)" "unprognostic (2.34e-1)" EEF1D "EF-1D, FLJ20897" ENSG00000104529 "Eukaryotic translation elongation factor 1 delta" P29692 8 143579697-143599541 "Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis, Transcription, Transcription regulation" "DNA-binding, Elongation factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric progenitor cells: 2150.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045101, HPA051002" Supported Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA 1200000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 24: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 40: Non-specific - Unknown function" "Cluster 67: Plasma cells - Plasma cell differentiation" 53 "Nucleoplasm, Nucleoli fibrillar center" "HPA045101: , HPA051002: " "unprognostic (3.43e-1)" "unprognostic (1.51e-2)" "unprognostic (3.29e-3)" "unprognostic (2.01e-1)" "unprognostic (3.28e-1)" "unprognostic (1.53e-1)" "unprognostic (1.92e-1)" "unprognostic (4.88e-3)" "unprognostic (5.35e-2)" "potential prognostic unfavorable (7.30e-5)" "unprognostic (1.45e-1)" "unprognostic (6.67e-2)" "unprognostic (2.45e-1)" "unprognostic (1.09e-3)" "unprognostic (4.55e-3)" "unprognostic (9.39e-2)" "unprognostic (3.50e-3)" "unprognostic (4.10e-3)" "unprognostic (4.47e-2)" "unprognostic (1.14e-1)" "unprognostic (1.70e-1)" "unprognostic (1.47e-2)" "unprognostic (3.12e-2)" "unprognostic (1.04e-1)" "unprognostic (6.74e-2)" "unprognostic (4.57e-2)" "unprognostic (1.74e-1)" "unprognostic (1.88e-1)" "unprognostic (1.02e-1)" "unprognostic (5.20e-2)" "unprognostic (1.16e-1)" EEF1E1 "AIMP3, P18" ENSG00000124802 "Eukaryotic translation elongation factor 1 epsilon 1" O43324 6 8073360-8102559 "Predicted intracellular proteins, Predicted membrane proteins" "Protein biosynthesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 212.3;Late spermatids: 222.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027901, HPA057866" Approved Supported Nucleoplasm,Cytosol NA NA 29000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 23 "Nucleoplasm, Cytosol" "HPA027901: , HPA057866: " "unprognostic (2.32e-1)" "potential prognostic unfavorable (1.99e-4)" "unprognostic (1.10e-1)" "unprognostic (1.27e-1)" "unprognostic (2.53e-1)" "unprognostic (9.35e-2)" "unprognostic (2.69e-2)" "unprognostic (6.48e-2)" "unprognostic (6.26e-2)" "unprognostic (2.18e-1)" "unprognostic (8.46e-2)" "unprognostic (1.78e-1)" "unprognostic (2.90e-1)" "validated prognostic unfavorable (5.97e-7)" "validated prognostic unfavorable (5.53e-4)" "unprognostic (4.12e-3)" "unprognostic (1.20e-1)" "unprognostic (1.34e-1)" "unprognostic (6.93e-2)" "unprognostic (1.74e-3)" "unprognostic (6.96e-3)" "unprognostic (9.93e-2)" "unprognostic (1.82e-2)" "unprognostic (6.08e-2)" "unprognostic (1.21e-1)" "unprognostic (3.93e-1)" "unprognostic (4.48e-3)" "unprognostic (7.66e-2)" "unprognostic (2.47e-1)" "unprognostic (8.66e-2)" "unprognostic (2.48e-2)" EEF1G EF1G ENSG00000254772 "Eukaryotic translation elongation factor 1 gamma" P26641 11 62559596-62574086 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Elongation factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 35.1;Brain inhibitory neurons: 32.2;Choroid plexus epithelial cells: 34.3;Colonocytes: 38.6;Enteric stem cells: 89.1;Enteric transient amplifying cells: 70.1;Enterocytes: 38.7;Ependymal cells: 30.7;Epididymal basal cells: 49.0;Epididymal efferent duct absorptive cells: 33.4;Goblet cells: 34.3;Microglia: 38.4;Oligodendrocytes: 33.8;Other brain neurons: 57.0;Paneth cells: 58.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040688, HPA055316" Enhanced Approved "Golgi apparatus,Cytosol" NA NA 7000000 "Cluster 18: Non-specific - Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 88 Cytosol "Golgi apparatus" "HPA040688: , HPA055316: " "unprognostic (9.88e-3)" "unprognostic (9.45e-3)" "unprognostic (1.70e-1)" "unprognostic (4.21e-2)" "unprognostic (8.71e-2)" "unprognostic (2.62e-1)" "unprognostic (6.83e-3)" "unprognostic (2.52e-3)" "unprognostic (3.32e-3)" "unprognostic (1.03e-1)" "potential prognostic favorable (9.67e-4)" "unprognostic (2.23e-3)" "unprognostic (3.07e-2)" "unprognostic (1.74e-3)" "unprognostic (9.90e-3)" "unprognostic (1.25e-2)" "unprognostic (1.14e-3)" "unprognostic (3.51e-2)" "unprognostic (9.67e-2)" "unprognostic (2.48e-2)" "unprognostic (2.72e-2)" "unprognostic (6.03e-2)" "unprognostic (1.66e-1)" "unprognostic (2.06e-1)" "unprognostic (1.38e-2)" "unprognostic (3.16e-2)" "unprognostic (8.19e-2)" "unprognostic (1.13e-1)" "unprognostic (3.66e-1)" "unprognostic (1.53e-1)" "unprognostic (1.09e-1)" EEF2 "EEF-2, EF2" ENSG00000167658 "Eukaryotic translation elongation factor 2" P13639 19 3976056-3985463 "Cancer-related genes, Disease related genes, Essential proteins, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Elongation factor, Hydrolase" "Cancer-related genes, Disease variant, FDA approved drug targets, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Decidual stromal cells: 2701.8;Pancreatic acinar cells: 2575.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007795, HPA040534, HPA057351" Enhanced Approved "Plasma membrane,Cytosol" NA NA 25000000 "Cluster 18: Non-specific - Translation" "Cluster 24: Non-specific - Transcription" "Cluster 47: Endothelial cells - Vasculature" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 66 "Plasma membrane, Cytosol" "CAB007795: , HPA040534: , HPA057351: " "unprognostic (8.33e-2)" "unprognostic (1.60e-2)" "unprognostic (5.34e-2)" "unprognostic (5.62e-3)" "unprognostic (2.09e-1)" "unprognostic (2.01e-1)" "unprognostic (9.38e-2)" "unprognostic (7.69e-2)" "unprognostic (1.64e-1)" "unprognostic (1.71e-1)" "potential prognostic favorable (2.48e-4)" "unprognostic (6.19e-3)" "unprognostic (2.53e-1)" "unprognostic (2.47e-3)" "unprognostic (4.40e-3)" "unprognostic (3.01e-1)" "unprognostic (1.02e-1)" "unprognostic (2.21e-1)" "unprognostic (3.96e-1)" "unprognostic (1.12e-2)" "unprognostic (1.18e-2)" "unprognostic (3.52e-2)" "unprognostic (1.40e-2)" "unprognostic (1.20e-1)" "unprognostic (2.43e-2)" "unprognostic (1.93e-1)" "unprognostic (2.63e-1)" "unprognostic (5.65e-2)" "unprognostic (1.15e-1)" "unprognostic (9.39e-2)" "potential prognostic favorable (3.75e-4)" EEF2K "CaMKIII, eEF-2K" ENSG00000103319 "Eukaryotic elongation factor 2 kinase" O00418 16 22206278-22288738 "Enzymes, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 45.9" "Cell type enhanced" "Detected in many" "Astrocytes: 60.0;Brain excitatory neurons: 50.5;Brain inhibitory neurons: 37.2;Choroid plexus epithelial cells: 56.6;Early spermatids: 47.2;Ependymal cells: 48.9;Late spermatids: 96.2;Microglia: 33.6;Oligodendrocyte progenitor cells: 58.0;Other brain neurons: 32.9;Papillary tip epithelial cells: 45.0;Podocytes: 48.3;Proximal tubule cells: 40.8;Renal collecting duct principal cells: 50.0;Tuft cells: 34.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Minor Salivary Gland - Smooth muscle cells, Prostate - Smooth muscle cells, Spleen - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007818, HPA056061" Approved Approved Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 102: Non-specific - Mixed function" 7 Nucleoplasm "CAB007818: , HPA056061: " "unprognostic (1.74e-1)" "unprognostic (3.38e-2)" "unprognostic (1.05e-1)" "unprognostic (6.27e-2)" "unprognostic (5.25e-2)" "unprognostic (2.26e-2)" "unprognostic (5.28e-3)" "unprognostic (1.63e-2)" "unprognostic (2.17e-1)" "unprognostic (3.10e-1)" "unprognostic (2.50e-1)" "unprognostic (2.19e-2)" "unprognostic (4.24e-2)" EEF2KMT "EFM3, FAM86A, MGC19636, SB153" ENSG00000118894 "Eukaryotic elongation factor 2 lysine methyltransferase" Q96G04 16 5084284-5097795 "Essential proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 13 "Early spermatids: 204.2;Late spermatids: 492.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" HPA041610 Approved Uncertain Vesicles NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 67: Testis - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 14 Vesicles "HPA041610: " "unprognostic (1.03e-2)" "unprognostic (2.62e-2)" "unprognostic (2.37e-2)" "unprognostic (1.96e-2)" "unprognostic (1.02e-1)" "unprognostic (1.17e-1)" "potential prognostic favorable (3.30e-4)" "unprognostic (5.94e-2)" "unprognostic (3.55e-1)" "unprognostic (2.59e-2)" "unprognostic (6.95e-2)" "unprognostic (1.93e-1)" "unprognostic (1.44e-3)" "unprognostic (1.29e-2)" "unprognostic (1.62e-2)" "unprognostic (4.69e-2)" "unprognostic (1.30e-1)" "unprognostic (7.33e-3)" "unprognostic (2.58e-1)" "potential prognostic unfavorable (2.51e-4)" "unprognostic (2.66e-1)" "unprognostic (1.47e-1)" "unprognostic (3.57e-2)" "unprognostic (8.18e-2)" "unprognostic (2.93e-1)" "unprognostic (1.52e-1)" "unprognostic (3.71e-1)" "unprognostic (1.68e-1)" "unprognostic (6.85e-2)" EEFSEC "EFSEC, SELB" ENSG00000132394 "Eukaryotic elongation factor, selenocysteine-tRNA specific" P57772 3 128153481-128408646 "Predicted intracellular proteins" "Protein biosynthesis" Hydrolase "Disease variant, Intellectual disability, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bergmann glia: 51.0;Brain inhibitory neurons: 52.6;Choroid plexus epithelial cells: 89.6;Distal convoluted tubule cells: 60.7;Loop of henle epithelial cells: 52.7;Microglia: 93.0;Oligodendrocyte progenitor cells: 66.9;Other brain neurons: 51.5;Podocytes: 52.4;Proximal tubule cells: 113.6;Renal collecting duct intercalated cells: 65.9;Renal collecting duct principal cells: 49.7;Renal connecting tubule cells: 66.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035795 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 4200 "Cluster 25: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 102: Non-specific - Mixed function" "Nucleoplasm, Nuclear bodies" Cytosol "HPA035795: " "unprognostic (8.23e-2)" "unprognostic (9.98e-3)" "unprognostic (1.04e-1)" "unprognostic (7.75e-2)" "unprognostic (1.11e-2)" "unprognostic (4.98e-2)" "unprognostic (1.75e-1)" "unprognostic (1.59e-1)" "unprognostic (1.83e-1)" "unprognostic (1.34e-2)" "unprognostic (1.26e-1)" "unprognostic (1.10e-1)" "unprognostic (2.34e-1)" "unprognostic (2.05e-3)" "potential prognostic favorable (1.44e-4)" "unprognostic (1.97e-2)" "unprognostic (4.19e-1)" "unprognostic (1.89e-2)" "unprognostic (6.81e-2)" "unprognostic (2.64e-1)" "unprognostic (4.46e-2)" "unprognostic (4.29e-1)" "potential prognostic favorable (2.21e-4)" "unprognostic (2.27e-1)" "unprognostic (9.61e-2)" "unprognostic (9.18e-2)" "unprognostic (1.08e-1)" "unprognostic (2.68e-1)" "unprognostic (2.09e-1)" EEPD1 KIAA1706 ENSG00000122547 "Endonuclease/exonuclease/phosphatase family domain containing 1" Q7L9B9 7 36153254-36301538 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 45.3" "Cell type enhanced" "Detected in many" "Adipocytes: 643.7;Cholangiocytes: 332.0;Cone photoreceptor cells: 256.7;Foveolar cells: 274.2;Myonuclei: 319.4;Neutrophil progenitors: 223.5;Neutrophils: 332.3;Pancreatic duct cells: 243.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 51.9;neutrophil: 46.7" "Group enriched" "Detected in many" 6 "granulocytes: 51.9;T-cells: 23.1" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053668 Approved "Nuclear speckles,Vesicles" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 24: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 89: Adipocytes - Lipid metabolism" "Nuclear speckles" Vesicles "HPA053668: " "unprognostic (6.75e-2)" "unprognostic (6.51e-2)" "unprognostic (4.59e-2)" "unprognostic (1.34e-1)" "unprognostic (1.06e-2)" "unprognostic (5.25e-3)" "unprognostic (1.59e-1)" "potential prognostic favorable (1.23e-5)" "unprognostic (1.20e-1)" "potential prognostic unfavorable (8.45e-4)" "unprognostic (3.06e-1)" "unprognostic (1.40e-1)" "unprognostic (8.62e-3)" "unprognostic (7.85e-2)" "unprognostic (2.58e-2)" "unprognostic (2.63e-3)" "unprognostic (2.25e-2)" "unprognostic (1.54e-2)" "unprognostic (4.79e-2)" "unprognostic (3.18e-1)" "unprognostic (2.64e-1)" "unprognostic (7.36e-2)" "unprognostic (8.03e-2)" "unprognostic (3.32e-2)" "unprognostic (1.15e-1)" "unprognostic (9.75e-3)" "unprognostic (2.06e-1)" "unprognostic (7.26e-3)" "unprognostic (1.70e-1)" "unprognostic (1.39e-2)" "unprognostic (1.04e-1)" EFCAB10 ENSG00000185055 "EF-hand calcium binding domain 10" A6NFE3 7 105565120-105600875 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "choroid plexus: 12.0;fallopian tube: 27.9;testis: 22.0" "Cell type enhanced" "Detected in many" "Early spermatids: 230.0;Endometrial ciliated cells: 155.1;Ependymal cells: 83.5;Epididymal efferent duct ciliated cells: 100.3;Fallopian tube ciliated cells: 201.7;Late primary spermatocytes: 279.6;Late spermatids: 106.2;Oocytes: 529.6;Respiratory ciliated cells: 236.3" "Cell type enriched" "Detected in many" 5 "ependymal cell: 105.7" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 13.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019751 Uncertain NA NA "Cluster 41: Basophils - Unknown function" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 1: Neuronal - Visual perception" "Cluster 107: Ciliated cells - Cilia assembly & function" "HPA019751: " "unprognostic (6.96e-3)" "unprognostic (1.76e-2)" "unprognostic (1.13e-1)" "unprognostic (4.76e-3)" "unprognostic (1.13e-1)" "unprognostic (1.10e-1)" "unprognostic (6.25e-3)" "unprognostic (2.96e-2)" "unprognostic (2.79e-2)" "potential prognostic unfavorable (1.58e-4)" "unprognostic (2.84e-2)" "unprognostic (8.71e-2)" "unprognostic (4.78e-2)" "unprognostic (2.65e-2)" "unprognostic (4.40e-2)" "unprognostic (2.24e-1)" "unprognostic (5.68e-2)" "unprognostic (1.48e-1)" "unprognostic (4.54e-2)" "unprognostic (2.69e-3)" "unprognostic (1.33e-1)" "unprognostic (6.39e-2)" "unprognostic (4.44e-2)" "unprognostic (2.63e-1)" "unprognostic (2.42e-1)" EFCAB11 C14orf143 ENSG00000140025 "EF-hand calcium binding domain 11" Q9BUY7 14 89794669-89954777 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 35.2" "Group enriched" "Detected in many" 7 "Early spermatids: 486.1;Late primary spermatocytes: 281.8;Late spermatids: 366.5" "Cell type enhanced" "Detected in some" "ependymal cell: 2.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 14.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA051209 Approved "Cell Junctions,Cytosol" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 67: Testis - Mixed function" "Cluster 46: Brainstem - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 7 "Cell Junctions, Cytosol" "HPA051209: " "unprognostic (2.99e-2)" "unprognostic (1.70e-1)" "unprognostic (1.52e-1)" "unprognostic (5.74e-2)" "unprognostic (4.73e-2)" "unprognostic (2.42e-2)" "unprognostic (2.56e-1)" "unprognostic (1.06e-3)" "unprognostic (8.46e-3)" "potential prognostic favorable (7.32e-6)" "unprognostic (2.40e-1)" "unprognostic (7.91e-2)" "unprognostic (4.44e-3)" "unprognostic (8.46e-3)" "unprognostic (1.80e-3)" "unprognostic (1.28e-1)" "unprognostic (6.09e-2)" "unprognostic (2.39e-1)" "unprognostic (4.09e-2)" "unprognostic (3.49e-3)" "unprognostic (1.54e-2)" "unprognostic (2.28e-2)" "unprognostic (5.63e-2)" "unprognostic (1.63e-1)" "unprognostic (1.32e-1)" "unprognostic (6.13e-2)" "unprognostic (8.23e-2)" "unprognostic (2.75e-1)" "unprognostic (4.53e-2)" "unprognostic (6.56e-2)" EFCAB12 C3orf25 ENSG00000172771 "EF-hand calcium binding domain 12" Q6NXP0 3 129401321-129428651 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 10.2;fallopian tube: 18.5" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 51.9;Early spermatids: 40.7;Endometrial ciliated cells: 61.1;Ependymal cells: 130.6;Epididymal efferent duct ciliated cells: 35.3;Fallopian tube ciliated cells: 72.0;Late spermatids: 29.9;Respiratory ciliated cells: 91.9" "Cell type enriched" "Detected in many" 4 "ependymal cell: 148.0" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 5.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "prostate cancer: 1.2" "Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "midbrain: 11.8" "HPA037694, HPA057532" Uncertain Supported Approved "Nucleoplasm,Nuclear bodies,Midbody ring" Yes NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 60: Prostate cancer - Unknown function" "Cluster 34: Ciliated cells - Cilia assembly & function" 2 Nucleoplasm "Nuclear bodies, Midbody ring" "HPA037694: , HPA057532: " "unprognostic (2.09e-2)" "unprognostic (6.33e-2)" "unprognostic (7.65e-2)" "unprognostic (7.74e-2)" "unprognostic (2.30e-2)" "unprognostic (6.77e-2)" "unprognostic (8.90e-2)" "unprognostic (3.16e-3)" "unprognostic (5.26e-1)" "unprognostic (3.03e-1)" EFCAB13 "C17orf57, FLJ40342" ENSG00000178852 "EF-hand calcium binding domain 13" Q8IY85 17 47323290-47441312 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 19.1" "Cell type enhanced" "Detected in many" "Adipocytes: 147.6;Cardiomyocytes: 173.6;Early primary spermatocytes: 192.7;Early spermatids: 246.9;Epicardial cells: 347.9;Fibro-adipogenic progenitors: 126.5;Late spermatids: 278.3;Podocytes: 268.9" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 125.6" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 11.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002501, HPA021633, HPA023249, HPA026561" Uncertain Enhanced "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 32: Basophils - Transcription" "Cluster 21: Testis - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "Nucleoplasm, Cytosol" "Nuclear speckles" "CAB002501: , HPA021633: , HPA023249: , HPA026561: " "unprognostic (2.30e-1)" "unprognostic (2.28e-2)" "unprognostic (8.80e-2)" "unprognostic (2.41e-2)" "unprognostic (3.23e-1)" "unprognostic (5.09e-3)" "unprognostic (4.67e-2)" "unprognostic (8.00e-2)" "unprognostic (1.74e-3)" "unprognostic (4.35e-2)" "unprognostic (1.27e-1)" "unprognostic (6.45e-2)" "unprognostic (6.51e-2)" "unprognostic (6.07e-2)" "unprognostic (5.03e-2)" "unprognostic (1.43e-1)" "potential prognostic favorable (6.56e-4)" "unprognostic (1.71e-1)" "unprognostic (3.63e-2)" "unprognostic (9.08e-3)" "unprognostic (1.81e-1)" "validated prognostic favorable (5.07e-4)" "validated prognostic favorable (1.47e-4)" "unprognostic (3.25e-1)" "unprognostic (2.06e-1)" "unprognostic (2.88e-1)" "unprognostic (1.66e-2)" "unprognostic (9.07e-2)" EFCAB14 KIAA0494 ENSG00000159658 "EF-hand calcium binding domain 14" O75071 1 46674659-46719146 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 150.0" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 501.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011224, HPA011938" Approved Approved "Nucleoli,Golgi apparatus,Cytosol" NA NA 70000 "Cluster 1: T-cells - Unknown function" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 69: Urothelial cells - Basic cellular functions" 9 Cytosol "Nucleoli, Golgi apparatus" "HPA011224: , HPA011938: " "unprognostic (3.03e-1)" "unprognostic (1.44e-1)" "unprognostic (8.32e-2)" "unprognostic (5.70e-2)" "unprognostic (1.91e-1)" "unprognostic (7.51e-2)" "unprognostic (2.57e-2)" "unprognostic (7.74e-3)" "unprognostic (4.46e-2)" "validated prognostic favorable (9.80e-10)" "validated prognostic favorable (9.89e-5)" "unprognostic (8.34e-2)" "unprognostic (5.58e-2)" "unprognostic (9.53e-2)" "unprognostic (1.69e-1)" "potential prognostic unfavorable (7.42e-4)" "unprognostic (1.20e-2)" "unprognostic (2.80e-2)" "unprognostic (1.59e-2)" "potential prognostic unfavorable (1.41e-4)" "unprognostic (1.32e-2)" "unprognostic (1.41e-1)" "unprognostic (9.21e-2)" "unprognostic (1.58e-1)" "unprognostic (3.04e-1)" "unprognostic (3.45e-2)" "unprognostic (2.40e-1)" "unprognostic (3.77e-2)" "unprognostic (2.73e-2)" EFCAB2 "CFAP200, DRC8, MGC12458" ENSG00000203666 "EF-hand calcium binding domain 2" Q5VUJ9 1 244969682-245127164 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Choroid plexus epithelial cells: 564.8;Ependymal cells: 865.0;Fallopian tube ciliated cells: 471.8;Myonuclei: 558.6;Respiratory ciliated cells: 700.7" "Cell type enhanced" "Detected in all" "ependymal cell: 878.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 5.4" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031206 Approved Approved "Plasma membrane,Mitochondria,Cytosol,Mid piece" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 34: Ciliated cells - Cilia assembly & function" "Plasma membrane, Cytosol, Mid piece" Mitochondria "HPA031206: " "unprognostic (9.54e-2)" "unprognostic (1.07e-1)" "unprognostic (3.33e-2)" "unprognostic (9.75e-2)" "unprognostic (4.43e-2)" "unprognostic (1.91e-1)" "unprognostic (6.79e-2)" "unprognostic (2.10e-1)" "unprognostic (2.19e-1)" "unprognostic (2.44e-2)" "unprognostic (1.21e-1)" "unprognostic (3.44e-2)" "unprognostic (1.80e-1)" "unprognostic (2.15e-3)" "unprognostic (8.71e-2)" "unprognostic (3.51e-2)" "unprognostic (1.35e-1)" "unprognostic (8.36e-3)" "unprognostic (2.27e-1)" "unprognostic (2.35e-1)" "unprognostic (8.34e-3)" "unprognostic (2.35e-2)" "unprognostic (2.73e-3)" "unprognostic (2.29e-2)" "unprognostic (3.48e-2)" "unprognostic (1.62e-1)" "unprognostic (2.85e-2)" "unprognostic (1.03e-1)" "unprognostic (1.91e-1)" "unprognostic (6.90e-3)" "unprognostic (1.38e-1)" EFCAB3 FLJ25818 ENSG00000172421 "EF-hand calcium binding domain 3" Q8N7B9 17 62343941-62416480 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 14 "testis: 5.5" "Cell type enriched" "Detected in some" 4 "Early spermatids: 139.2" "Cell type enhanced" "Detected in some" "deep-layer corticothalamic and 6b: 5.3" "Cancer enhanced" "Detected in single" "Kidney Renal Clear Cell Carcinoma (TCGA): 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA046862 Uncertain NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 15: Kidney cancer - Membrane components" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" "HPA046862: " "unprognostic (1.36e-2)" "unprognostic (2.91e-1)" "potential prognostic unfavorable (5.99e-4)" EFCAB5 FLJ46247 ENSG00000176927 "EF-hand calcium binding domain 5" A4FU69 17 29929200-30108452 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "testis: 8.0" "Group enriched" "Detected in many" 4 "Cardiomyocytes: 146.4;Early primary spermatocytes: 61.8;Early spermatids: 201.3;Late primary spermatocytes: 207.1;Late spermatids: 167.6" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.4;eosinophil: 3.2" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in single" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA022852 Approved "Nuclear bodies,Mitochondria" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 57: Testis - Spermatogenesis" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 15: Kidney cancer - Membrane components" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" "Nuclear bodies" Mitochondria "HPA022852: " "unprognostic (6.46e-2)" "unprognostic (1.03e-3)" "unprognostic (1.02e-1)" EFCAB6 "dJ185D5.1, DJBP, FLJ23588, HSCBCIP1, KIAA1672" ENSG00000186976 "EF-hand calcium binding domain 6" Q5THR3 22 43528744-43812337 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "fallopian tube: 7.2;testis: 22.7" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 305.6;Early spermatids: 473.2;Endometrial ciliated cells: 226.3;Ependymal cells: 733.1;Fallopian tube ciliated cells: 223.7;Late spermatids: 802.6;Respiratory ciliated cells: 516.7" "Group enriched" "Detected in all" 4 "choroid plexus epithelial cell: 239.0;ependymal cell: 804.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA003098, HPA018946" Supported "Nucleoplasm,Mid piece,Principal piece" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" 2 Nucleoplasm "Mid piece, Principal piece" "HPA003098: , HPA018946: " "unprognostic (1.29e-1)" "unprognostic (3.38e-1)" "unprognostic (3.01e-1)" "validated prognostic favorable (4.00e-8)" "validated prognostic favorable (1.06e-5)" "unprognostic (4.02e-2)" "unprognostic (5.37e-2)" "unprognostic (2.51e-3)" "unprognostic (1.01e-2)" EFCAB7 "KIAA1799, RP4-534K7.1" ENSG00000203965 "EF-hand calcium binding domain 7" A8K855 1 63523372-63572693 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 92.2;Late primary spermatocytes: 138.8;Thymic myoid cells: 239.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 10.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029611, HPA029612, HPA029613" Enhanced Approved "Primary cilium,Cytosol" NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 31: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 2 "Primary cilium, Cytosol" "HPA029611: , HPA029612: , HPA029613: " "unprognostic (3.05e-2)" "unprognostic (5.88e-2)" "unprognostic (1.21e-2)" "unprognostic (2.73e-3)" "unprognostic (2.09e-1)" "unprognostic (4.31e-1)" "unprognostic (3.92e-3)" "unprognostic (1.41e-1)" "unprognostic (3.68e-2)" "potential prognostic unfavorable (1.67e-4)" "potential prognostic favorable (5.32e-6)" "unprognostic (7.42e-3)" "unprognostic (1.27e-1)" "potential prognostic unfavorable (3.66e-4)" "unprognostic (1.11e-1)" "unprognostic (3.83e-1)" "unprognostic (9.03e-2)" "unprognostic (2.80e-1)" "unprognostic (1.14e-1)" "unprognostic (2.39e-1)" "unprognostic (7.06e-2)" "unprognostic (1.22e-1)" "unprognostic (1.29e-1)" "unprognostic (1.86e-1)" "unprognostic (7.83e-3)" "unprognostic (1.47e-2)" "unprognostic (4.42e-2)" "unprognostic (1.85e-1)" "unprognostic (4.93e-2)" "unprognostic (2.51e-1)" "unprognostic (2.66e-1)" EFCAB8 ENSG00000215529 "EF-hand calcium binding domain 8" A8MWE9 20 32858923-32961845 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 9 "testis: 3.4" "Cell type enhanced" "Detected in many" "Early spermatids: 11.3;Epididymal clear cells: 8.2;Innate lymphoid cells: 12.2;Late primary spermatocytes: 18.2;Neutrophils: 18.0;Pancreatic islet cells: 8.4;Pituitary stem cells: 15.4" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "CAB034246, HPA042751" Uncertain NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 59: Leukemia - T-cell receptor" "Cluster 24: Neutrophils - Innate immunity signal integration" "CAB034246: , HPA042751: " EFCAB9 ENSG00000214360 "EF-hand calcium binding domain 9" A8MZ26 5 172194172-172203454 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 41 "testis: 9.5" "Group enriched" "Detected in some" 9 "Early spermatids: 93.2;Late primary spermatocytes: 83.0;Late spermatids: 35.4" "Cell type enhanced" "Detected in single" "Bergmann glia: 1.7" "Not detected" "Not detected" "Region enriched" "Detected in single" 10 "cerebellum: 3.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 35: Non-specific - DNA binding" "Cluster 55: Lymphoma - Immune response" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" EFCC1 "C3orf73, CCDC48, FLJ12057" ENSG00000114654 "EF-hand and coiled-coil domain containing 1" Q9HA90 3 129001304-129040742 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lung: 3.8;ovary: 3.6" "Cell type enhanced" "Detected in many" "Early spermatids: 51.2;Ependymal cells: 19.0;Hematopoietic stem cells: 49.5;Late spermatids: 199.4;Lymphatic endothelial cells: 59.5;Thyrotrophs: 17.1;Vascular endothelial cells: 17.3" "Cell type enhanced" "Detected in many" "endothelial cell: 25.3;ependymal cell: 21.1;fibroblast: 51.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "cervical cancer: 1.6" "Colon - Enteric glia cells, Liver - Hepatic stellate cells" "Low region specificity" "Detected in many" "HPA042798, HPA050888, HPA076069" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 13: Lung - Secretion" "Cluster 24: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" Nucleoplasm Cytosol "HPA042798: , HPA050888: , HPA076069: " "unprognostic (1.12e-1)" "unprognostic (2.51e-1)" "unprognostic (1.23e-2)" "unprognostic (8.47e-2)" "unprognostic (4.67e-3)" "unprognostic (1.51e-1)" "unprognostic (9.42e-2)" "unprognostic (6.69e-2)" "unprognostic (7.08e-3)" "unprognostic (2.99e-2)" "unprognostic (1.28e-2)" "unprognostic (1.79e-1)" EFEMP1 "DHRD, FBLN3, FBNL, MTLV, S1-5" ENSG00000115380 "EGF containing fibulin extracellular matrix protein 1" Q12805 2 55865967-55924139 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Disease variant, Glaucoma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 977.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 310.4;Astrocytes: 475.1;Breast myoepithelial cells: 367.7;Choroid plexus epithelial cells: 496.3;Cytotrophoblasts: 1819.7;Fibroblasts: 392.4;Hepatic stellate cells: 393.7;Lymphatic endothelial cells: 568.7;Mesothelial cells: 404.4;Migrating cytotrophoblasts: 660.3;Retinal pigment epithelial cells: 370.9;Syncytiotrophoblasts: 1002.0" "Group enriched" "Detected in many" 7 "astrocyte: 630.9;Bergmann glia: 304.7;choroid plexus epithelial cell: 309.3;ependymal cell: 292.5" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 233.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 474.4" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Fibroblasts, Breast - Fibroblasts, Heart muscle - Fibroblasts, Lung - Fibroblasts_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_2, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016368, HPA049806, HPA070841, HPA071588" Supported Supported Mitochondria "Secreted to extracellular matrix" "Growth factor" NA NA 1500000000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 46: Brainstem - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 42 Mitochondria "CAB016368: , HPA049806: , HPA070841: , HPA071588: " "unprognostic (8.22e-2)" "unprognostic (7.30e-3)" "unprognostic (3.35e-2)" "unprognostic (1.55e-1)" "unprognostic (1.05e-2)" "unprognostic (1.06e-1)" "unprognostic (1.94e-2)" "unprognostic (3.55e-3)" "unprognostic (1.99e-2)" "unprognostic (1.05e-2)" "unprognostic (3.92e-2)" "potential prognostic unfavorable (5.17e-4)" "potential prognostic unfavorable (4.50e-6)" "unprognostic (1.50e-1)" "unprognostic (8.06e-3)" "unprognostic (5.09e-2)" "unprognostic (2.47e-1)" "unprognostic (1.22e-1)" "unprognostic (2.81e-2)" "unprognostic (1.16e-1)" "unprognostic (5.51e-2)" "unprognostic (2.91e-2)" "unprognostic (3.26e-1)" "unprognostic (1.30e-1)" "unprognostic (1.77e-1)" "unprognostic (3.69e-2)" "unprognostic (1.57e-1)" "unprognostic (7.97e-3)" "unprognostic (6.31e-2)" "unprognostic (2.29e-1)" "unprognostic (3.26e-2)" EFEMP2 "FBLN4, UPH1" ENSG00000172638 "EGF containing fibulin extracellular matrix protein 2" O95967 11 65866441-65873592 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 65.4;Decidual stromal cells: 272.6;Fibroblasts: 96.9;Granulosa cells: 65.7;Hepatic stellate cells: 148.5;Late primary spermatocytes: 107.4;Ovarian stromal cells: 95.4;Peritubular myoid cells: 99.6;Smooth muscle cells: 70.3" "Cell type enhanced" "Detected in many" "astrocyte: 32.9;fibroblast: 36.7;pericyte: 48.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.7" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Fibroblasts, Breast - Fibroblasts, Colon - Enteric glia cells, Kidney - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023270 Approved "Secreted to extracellular matrix" "No annotated function" NA NA 3800000 "Cluster 21: Neutrophils - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 44: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 93 "HPA023270: " "unprognostic (9.67e-2)" "unprognostic (1.46e-1)" "unprognostic (2.56e-1)" "unprognostic (5.41e-3)" "unprognostic (5.48e-3)" "unprognostic (1.74e-1)" "unprognostic (1.12e-3)" "potential prognostic unfavorable (9.75e-7)" "unprognostic (1.32e-1)" "unprognostic (4.02e-2)" "unprognostic (1.92e-2)" "unprognostic (7.85e-2)" "potential prognostic favorable (5.78e-4)" "unprognostic (7.72e-2)" "unprognostic (6.97e-3)" "unprognostic (2.21e-1)" "unprognostic (1.47e-2)" "unprognostic (6.69e-3)" "unprognostic (1.07e-1)" "unprognostic (4.75e-2)" "unprognostic (1.09e-2)" "unprognostic (2.54e-2)" "unprognostic (3.93e-1)" "unprognostic (1.63e-2)" "unprognostic (9.53e-2)" "unprognostic (6.77e-2)" "unprognostic (1.72e-2)" "unprognostic (1.62e-2)" "unprognostic (5.71e-2)" "unprognostic (1.67e-1)" "unprognostic (1.79e-1)" EFHB "CFAP21, FLJ25200" ENSG00000163576 "EF-hand domain family member B" Q8N7U6 3 19879472-19947025 "Predicted intracellular proteins" "Calcium transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 16.0;testis: 14.5" "Cell type enhanced" "Detected in many" "Early spermatids: 57.0;Endometrial ciliated cells: 81.5;Ependymal cells: 136.1;Epididymal efferent duct ciliated cells: 176.3;Fallopian tube ciliated cells: 152.0;Late primary spermatocytes: 96.5;Respiratory ciliated cells: 152.2" "Cell type enriched" "Detected in many" 7 "ependymal cell: 166.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 2.7;Kidney cancer: 4.1" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA034835 Approved "Nuclear bodies,Vesicles,Cytosol,Connecting piece" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 34: Ciliated cells - Cilia assembly & function" 1 Cytosol "Nuclear bodies, Vesicles, Connecting piece" "HPA034835: " "unprognostic (1.50e-1)" "unprognostic (3.96e-3)" "unprognostic (2.95e-1)" "unprognostic (8.04e-3)" "unprognostic (3.09e-1)" "unprognostic (4.42e-1)" "unprognostic (1.26e-1)" "unprognostic (2.19e-2)" EFHC1 "EJM, EJM1, FLJ10466, POC9, RIB72" ENSG00000096093 "EF-hand domain containing 1" Q5JVL4 6 52362123-52529886 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "fallopian tube: 32.5" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 352.3;Endometrial ciliated cells: 432.2;Ependymal cells: 456.8;Epididymal efferent duct ciliated cells: 481.4;Fallopian tube ciliated cells: 483.2;Respiratory ciliated cells: 663.6" "Group enriched" "Detected in all" 4 "choroid plexus epithelial cell: 353.8;ependymal cell: 505.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 6.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035307 Approved Uncertain "Plasma membrane,Cytosol,Equatorial segment,Mid piece,Principal piece,End piece" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" 64 "Plasma membrane, Mid piece, Principal piece, End piece" "Cytosol, Equatorial segment" "HPA035307: " "unprognostic (5.48e-2)" "unprognostic (1.60e-2)" "unprognostic (2.26e-2)" "unprognostic (1.83e-1)" "unprognostic (5.58e-2)" "unprognostic (9.94e-2)" "unprognostic (2.85e-1)" "unprognostic (7.40e-2)" "unprognostic (1.55e-1)" "unprognostic (7.01e-2)" "unprognostic (6.19e-2)" "unprognostic (8.55e-2)" "unprognostic (5.74e-2)" "unprognostic (7.51e-2)" "unprognostic (1.36e-1)" "unprognostic (1.68e-1)" "unprognostic (2.40e-2)" "unprognostic (2.74e-1)" "unprognostic (2.18e-1)" "unprognostic (2.25e-2)" "unprognostic (7.92e-3)" "unprognostic (2.18e-2)" "unprognostic (1.29e-1)" "unprognostic (6.04e-2)" "unprognostic (9.71e-2)" "unprognostic (1.46e-1)" "unprognostic (1.11e-1)" "unprognostic (1.58e-1)" "unprognostic (4.36e-2)" "unprognostic (1.54e-1)" EFHC2 "FLJ22843, MRX74" ENSG00000183690 "EF-hand domain containing 2" Q5JST6 X 44147872-44343672 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 26.4;fallopian tube: 13.8" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 392.9;Endometrial ciliated cells: 186.7;Ependymal cells: 360.8;Epididymal efferent duct ciliated cells: 146.5;Fallopian tube ciliated cells: 237.0;Platelets: 115.7;Respiratory ciliated cells: 296.5" "Group enriched" "Detected in many" 5 "choroid plexus epithelial cell: 323.0;ependymal cell: 415.5" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "choroid plexus: 36.5" "Group enriched" "Detected in some" 7 "basophil: 16.3;NK-cell: 5.8" "Group enriched" "Detected in many" 7 "granulocytes: 16.3;NK-cells: 5.8" "Cancer enhanced" "Detected in some" "Bile duct cancer: 1.2;Leukemia: 1.6" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034492 Approved Supported NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 34: Ciliated cells - Cilia assembly & function" 85 "HPA034492: " "unprognostic (7.49e-2)" "unprognostic (1.14e-1)" "unprognostic (2.10e-2)" "unprognostic (6.01e-3)" "potential prognostic unfavorable (4.40e-4)" "unprognostic (2.03e-3)" "potential prognostic favorable (2.64e-4)" "potential prognostic favorable (6.77e-4)" "unprognostic (4.78e-3)" "unprognostic (4.02e-1)" "unprognostic (5.52e-2)" "unprognostic (6.38e-3)" "unprognostic (6.17e-2)" "unprognostic (5.56e-2)" "unprognostic (2.85e-3)" "unprognostic (1.26e-1)" EFHD1 FLJ13612 ENSG00000115468 "EF-hand domain family member D1" Q9BUP0 2 232606057-232682776 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 313.4;brain: 324.6" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 452.1;Breast lactating cells: 304.7;Distal convoluted tubule cells: 262.3;Hepatocytes: 174.2;Loop of henle epithelial cells: 281.4;Migrating cytotrophoblasts: 238.9;Oligodendrocytes: 216.3;Pericytes: 187.4;Renal collecting duct intercalated cells: 281.7;Syncytiotrophoblasts: 426.3;Vascular smooth muscle cells: 259.2" "Cell type enhanced" "Detected in all" "oligodendrocyte: 275.2;pericyte: 271.6;vascular associated smooth muscle cell: 190.6" "Group enriched" "Detected in all" 4 "Breast Invasive Carcinoma (TCGA): 314.4;Kidney Chromophobe (TCGA): 235.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.2" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in many" 5 "breast cancer: 172.9" "Breast - Breast glandular cells, Breast - Breast glandular cells, Pituitary gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049331, HPA056959" Enhanced Supported "Nucleoli fibrillar center,Golgi apparatus" No NA "Cluster 21: Neutrophils - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 27: Breast cancer - Unknown function" "Cluster 110: Mural cells - ECM organization" 12 "Golgi apparatus" "Nucleoli fibrillar center" "HPA049331: , HPA056959: " "unprognostic (5.17e-2)" "unprognostic (5.49e-3)" "unprognostic (7.17e-2)" "unprognostic (7.30e-3)" "unprognostic (2.75e-2)" "unprognostic (9.60e-2)" "unprognostic (1.55e-1)" "unprognostic (2.14e-1)" "unprognostic (7.86e-2)" "unprognostic (4.20e-3)" "validated prognostic favorable (5.51e-6)" "validated prognostic favorable (4.24e-4)" "unprognostic (3.65e-3)" "unprognostic (9.24e-2)" "unprognostic (4.98e-3)" "unprognostic (1.78e-1)" "unprognostic (4.69e-3)" "unprognostic (1.32e-2)" "unprognostic (1.89e-1)" "unprognostic (8.77e-2)" "unprognostic (7.88e-2)" "unprognostic (8.20e-2)" "unprognostic (1.19e-1)" "unprognostic (7.45e-2)" "unprognostic (1.12e-2)" "unprognostic (2.83e-2)" "unprognostic (4.23e-2)" "unprognostic (1.35e-2)" "unprognostic (2.26e-1)" "unprognostic (3.95e-2)" "unprognostic (1.24e-2)" EFHD2 MGC4342 ENSG00000142634 "EF-hand domain family member D2" Q96C19 1 15409888-15430339 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 290.1;Extravillous trophoblasts: 304.5;Foveolar cells: 395.2;Hofbauer cells: 289.6;Late spermatids: 355.1;monocytes: 406.3;Neutrophils: 927.6;Pancreatic acinar cells: 455.3;Urothelial cells: 276.9" "Cell type enhanced" "Detected in all" "deep-layer near-projecting: 185.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 133.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Macrophages, Prostate - Urothelial cells, Spleen - Neutrophils_2, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048961 Enhanced Approved Cytosol No No 250000 "Cluster 7: Non-specific - Innate immune response" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 24: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 2 Cytosol "HPA048961: " "unprognostic (9.09e-2)" "unprognostic (2.78e-3)" "unprognostic (2.32e-2)" "unprognostic (3.43e-2)" "unprognostic (1.15e-1)" "unprognostic (1.31e-1)" "unprognostic (1.75e-2)" "unprognostic (7.09e-2)" "unprognostic (2.64e-2)" "unprognostic (2.02e-2)" "unprognostic (1.46e-2)" "unprognostic (8.90e-2)" "unprognostic (8.03e-2)" "unprognostic (6.90e-2)" "unprognostic (1.17e-2)" "potential prognostic unfavorable (9.87e-4)" "unprognostic (1.35e-2)" "unprognostic (6.25e-2)" "unprognostic (1.02e-1)" "unprognostic (1.20e-2)" "unprognostic (2.15e-2)" "unprognostic (1.06e-1)" "unprognostic (3.38e-1)" "unprognostic (4.98e-2)" "unprognostic (7.92e-3)" "unprognostic (3.87e-1)" "unprognostic (1.68e-1)" "unprognostic (7.92e-2)" "unprognostic (7.71e-2)" "potential prognostic favorable (7.91e-4)" "unprognostic (1.37e-1)" EFL1 "EFTUD1, FAM42A, FLJ13119, HsT19294, RIA1" ENSG00000140598 "Elongation factor like GTPase 1" Q7Z2Z2 15 82130206-82262773 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Protein biosynthesis, Ribosome biogenesis" "Elongation factor, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039654, HPA047110, HPA052345" Uncertain Approved Cytosol NA NA 14000 "Cluster 25: Non-specific - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 58: Non-specific - Nuclear processes" "Cluster 69: Urothelial cells - Basic cellular functions" 5 Cytosol "HPA039654: , HPA047110: , HPA052345: " "unprognostic (1.66e-2)" "unprognostic (1.67e-1)" "unprognostic (1.05e-1)" "unprognostic (9.39e-2)" "unprognostic (1.39e-1)" "unprognostic (2.05e-1)" "potential prognostic favorable (5.86e-4)" "unprognostic (1.78e-1)" "unprognostic (1.71e-2)" "potential prognostic favorable (1.65e-7)" "unprognostic (1.10e-2)" "unprognostic (3.04e-2)" "potential prognostic unfavorable (6.23e-4)" "unprognostic (2.60e-1)" "unprognostic (2.42e-3)" "unprognostic (3.32e-1)" "unprognostic (1.06e-1)" "unprognostic (5.62e-2)" "unprognostic (1.35e-1)" "unprognostic (3.69e-2)" "unprognostic (1.03e-1)" "unprognostic (3.37e-1)" "unprognostic (8.14e-3)" "unprognostic (8.00e-2)" "unprognostic (1.66e-1)" "unprognostic (1.13e-1)" "unprognostic (3.02e-2)" "unprognostic (1.20e-1)" "unprognostic (7.22e-3)" EFNA1 "ECKLG, EPLG1, GMAN, LERK1, TNFAIP4" ENSG00000169242 "Ephrin A1" P20827 1 155127876-155134899 "Cancer-related genes, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 476.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 298.6;Extravillous trophoblasts: 1373.1;Migrating cytotrophoblasts: 583.3;Prostatic club cells: 256.4;Syncytiotrophoblasts: 299.2" "Group enriched" "Detected in many" 4 "endothelial cell: 55.9;oligodendrocyte: 35.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "naive CD4 T-cell: 11.5;naive CD8 T-cell: 5.9" "Lineage enriched" "Detected in single" 23 "T-cells: 11.5" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Lung - Alveolar cells type 1, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069549 Approved "Secreted to blood" "Developmental protein" NA Yes 790000 1000000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 7 "HPA069549: " "unprognostic (6.81e-3)" "unprognostic (1.45e-1)" "unprognostic (1.66e-2)" "unprognostic (2.65e-3)" "unprognostic (1.56e-1)" "unprognostic (1.51e-1)" "unprognostic (7.51e-2)" "unprognostic (4.56e-2)" "unprognostic (1.28e-2)" "unprognostic (4.46e-1)" "validated prognostic favorable (2.97e-4)" "validated prognostic favorable (5.02e-7)" "unprognostic (1.41e-1)" "unprognostic (1.86e-3)" "unprognostic (4.33e-2)" "unprognostic (1.12e-1)" "unprognostic (2.49e-2)" "unprognostic (3.44e-2)" "unprognostic (3.11e-1)" "unprognostic (7.41e-2)" "unprognostic (5.59e-3)" "unprognostic (1.42e-2)" "unprognostic (2.46e-1)" "unprognostic (1.58e-1)" "unprognostic (3.61e-2)" "unprognostic (1.18e-2)" "unprognostic (1.14e-1)" "unprognostic (2.94e-1)" "unprognostic (3.45e-1)" "unprognostic (1.85e-1)" "unprognostic (1.58e-1)" EFNA2 "ELF-1, EPLG6, LERK6" ENSG00000099617 "Ephrin A2" O43921 19 1285873-1301431 "Cancer-related genes, Predicted intracellular proteins, RAS pathway related proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "gallbladder: 3.3;intestine: 11.6;liver: 12.6" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 49.1;Colonocytes: 68.3;Enteric stem cells: 29.2;Enteric transient amplifying cells: 39.2;Enterocytes: 60.0;Epididymal basal cells: 36.2;Gastric progenitor cells: 19.2;Goblet cells: 20.9;Paneth cells: 23.2" "Cell type enhanced" "Detected in many" "oligodendrocyte precursor cell: 14.9" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 16.2;Rectum Adenocarcinoma (TCGA): 16.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 9.0" "Colon - Colon enterocytes, Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067567 Approved Mitochondria,Cytosol "Intracellular and membrane" "No annotated function" NA NA "Cluster 77: Intestine - Digestion" "Cluster 38: Sub-cortical - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 20: Non-specific - Transcription regulation" 33 "Mitochondria, Cytosol" "HPA067567: " "unprognostic (3.03e-2)" "unprognostic (1.13e-2)" "unprognostic (7.54e-3)" "potential prognostic favorable (9.43e-4)" "unprognostic (1.10e-1)" "unprognostic (2.56e-2)" "unprognostic (6.25e-2)" "unprognostic (7.93e-2)" "unprognostic (5.19e-3)" "potential prognostic unfavorable (3.24e-4)" "unprognostic (1.00e-2)" "unprognostic (3.02e-2)" "unprognostic (2.90e-1)" "unprognostic (1.55e-2)" "unprognostic (2.64e-1)" "unprognostic (6.90e-2)" "unprognostic (7.22e-2)" "unprognostic (2.09e-2)" EFNA3 "Ehk1-L, EPLG3, LERK3" ENSG00000143590 "Ephrin A3" P52797 1 155078837-155087538 "Essential proteins, Predicted membrane proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 29.0;skin 1: 94.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 48.0;Breast secretory cells: 33.3;Esophageal apical cells: 132.9;Esophageal basal cells: 33.0;Esophageal suprabasal cells: 119.0;Extravillous trophoblasts: 43.6;Oocytes: 96.7;Suprabasal keratinocytes: 84.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010494 Uncertain NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 2: Non-specific - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 85: Squamous epithelial cells - Keratinization" 7 "CAB010494: " "unprognostic (4.63e-2)" "unprognostic (4.44e-2)" "unprognostic (1.19e-1)" "unprognostic (5.30e-3)" "unprognostic (1.58e-1)" "unprognostic (2.24e-2)" "unprognostic (3.39e-1)" "potential prognostic favorable (9.29e-4)" "unprognostic (1.18e-1)" "potential prognostic unfavorable (1.45e-4)" "unprognostic (6.17e-2)" "unprognostic (1.48e-1)" "validated prognostic unfavorable (2.89e-6)" "validated prognostic unfavorable (1.83e-5)" "unprognostic (2.73e-3)" "unprognostic (1.33e-2)" "unprognostic (3.44e-2)" "unprognostic (2.52e-3)" "unprognostic (6.83e-2)" "unprognostic (3.10e-2)" "unprognostic (7.08e-2)" "unprognostic (2.04e-1)" "unprognostic (2.76e-1)" "unprognostic (3.29e-3)" "unprognostic (1.30e-1)" "unprognostic (6.61e-2)" "potential prognostic favorable (6.52e-4)" "unprognostic (2.59e-2)" "unprognostic (2.05e-1)" "unprognostic (1.90e-1)" EFNA4 "EPLG4, LERK4" ENSG00000243364 "Ephrin A4" P52798 1 155063737-155069553 "Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 29.2" "Cell type enhanced" "Detected in some" "Astrocytes: 1.7;Choroid plexus epithelial cells: 1.3;Ependymal cells: 1.7;Gastric chief cells: 1.1;Microglia: 2.2;Oligodendrocytes: 1.1" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 3.3;leukocyte: 3.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" CAB021350 Uncertain "Secreted to blood" "No annotated function" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 58: Skin - Keratinization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Non-specific - Basic cellular functions" 7 "CAB021350: " "unprognostic (9.03e-2)" "unprognostic (9.01e-2)" "unprognostic (5.05e-1)" "unprognostic (3.73e-3)" "unprognostic (2.23e-1)" "unprognostic (1.42e-1)" "unprognostic (5.76e-3)" "unprognostic (8.57e-2)" "unprognostic (1.58e-1)" "unprognostic (2.47e-2)" "potential prognostic unfavorable (6.47e-4)" "unprognostic (1.52e-3)" "unprognostic (3.25e-1)" "potential prognostic unfavorable (2.20e-5)" "unprognostic (5.44e-2)" "unprognostic (3.69e-1)" "unprognostic (4.60e-2)" "unprognostic (5.57e-2)" "unprognostic (8.38e-2)" "unprognostic (1.32e-2)" "unprognostic (1.61e-1)" "unprognostic (9.17e-3)" "unprognostic (2.70e-1)" "unprognostic (5.69e-2)" "unprognostic (1.17e-1)" "unprognostic (1.72e-1)" "unprognostic (2.32e-1)" "unprognostic (1.74e-3)" "unprognostic (1.82e-2)" "unprognostic (1.57e-1)" "unprognostic (1.28e-2)" EFNA4-EFNA3 ENSG00000251246 "EFNA4-EFNA3 readthrough" 1 155063748-155086807 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.2;Mucous neck cells: 1.6;Paneth cells: 3.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 24: Neurons - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "unprognostic (1.49e-1)" "unprognostic (5.60e-2)" EFNA5 "AF1, EPLG7, LERK7" ENSG00000184349 "Ephrin A5" P52803 5 107376894-107670937 "Cancer-related genes, Predicted membrane proteins, RAS pathway related proteins" "Differentiation, Neurogenesis" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 1532.3;Lactotrophs: 946.3;Mesothelial cells: 1166.8;Pituicytes/FSCs: 1942.0;Salivary ionocytes: 1075.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Prostate - Urothelial cells, Skin - Outer root sheath cells, Spleen - Fibroblasts_1, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013282, HPA054047" Approved Approved Vesicles,Cytosol NA Yes 8300 "Cluster 15: NK-cells - Unknown function" "Cluster 58: Skin - Keratinization" "Cluster 53: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 40 "Vesicles, Cytosol" "CAB013282: , HPA054047: " "unprognostic (1.62e-2)" "unprognostic (2.57e-1)" "unprognostic (2.97e-1)" "unprognostic (2.85e-2)" "unprognostic (5.54e-3)" "potential prognostic unfavorable (5.43e-4)" "unprognostic (8.35e-3)" "unprognostic (2.72e-1)" "unprognostic (7.02e-2)" "unprognostic (6.79e-2)" "potential prognostic unfavorable (3.83e-7)" "unprognostic (1.17e-3)" "unprognostic (1.30e-2)" "unprognostic (1.69e-1)" "potential prognostic unfavorable (1.66e-4)" "unprognostic (1.55e-1)" "unprognostic (7.79e-2)" "unprognostic (1.64e-1)" "unprognostic (1.26e-3)" "unprognostic (5.77e-2)" "potential prognostic unfavorable (8.03e-4)" "unprognostic (1.56e-3)" "unprognostic (1.28e-1)" "unprognostic (4.71e-2)" "unprognostic (4.34e-1)" "unprognostic (8.20e-3)" "unprognostic (1.76e-1)" "potential prognostic unfavorable (6.16e-4)" EFNB1 "CFNS, Elk-L, EPLG2, LERK2" ENSG00000090776 "Ephrin B1" P98172 X 68829021-68842160 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Cancer-related genes, Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 112.0;Colonocytes: 53.1;Esophageal basal cells: 74.7;Extravillous trophoblasts: 119.5;Foveolar cells: 55.4;Podocytes: 77.4;Suprabasal keratinocytes: 88.5;Urothelial cells: 67.1;Vascular endothelial cells: 51.4" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 12.5;fibroblast: 14.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 3.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Kidney - Endothelial cells, Liver - Vascular endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB031489, HPA067188" Uncertain Supported "Plasma membrane" NA NA 990000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 58: Skin - Keratinization" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 30 "Plasma membrane" "CAB031489: , HPA067188: " "unprognostic (2.86e-1)" "unprognostic (1.97e-2)" "unprognostic (4.18e-3)" "unprognostic (1.81e-2)" "unprognostic (2.23e-1)" "unprognostic (2.06e-1)" "unprognostic (2.95e-1)" "unprognostic (1.11e-1)" "unprognostic (1.00e-2)" "unprognostic (1.15e-1)" "potential prognostic favorable (3.51e-4)" "unprognostic (3.49e-1)" "unprognostic (4.76e-3)" "unprognostic (1.16e-2)" "unprognostic (4.71e-2)" "unprognostic (1.98e-1)" "unprognostic (9.84e-3)" "unprognostic (2.24e-1)" "unprognostic (2.06e-1)" "unprognostic (7.40e-2)" "unprognostic (1.46e-1)" "potential prognostic unfavorable (5.49e-4)" "unprognostic (9.94e-2)" "unprognostic (2.24e-2)" "unprognostic (2.65e-1)" "unprognostic (1.09e-1)" "unprognostic (1.68e-3)" "unprognostic (3.51e-2)" "unprognostic (8.47e-2)" "unprognostic (8.20e-2)" "unprognostic (6.54e-2)" EFNB2 "EPLG5, Htk-L, HTKL, LERK5, MGC126226, MGC126227, MGC126228" ENSG00000125266 "Ephrin B2" P52799 13 106489745-106535662 "Cancer-related genes, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Differentiation, Host-virus interaction, Neurogenesis" "Developmental protein, Host cell receptor for virus entry, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Colonocytes: 179.3;Foveolar cells: 209.3;Lymphatic endothelial cells: 192.0;Prostatic glandular cells: 224.6;Salivary basal cells: 181.9;Suprabasal keratinocytes: 202.3;Vascular endothelial cells: 297.9" "Cell type enhanced" "Detected in all" "endothelial cell: 278.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Lung - Endothelial cells, Thyroid gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008999, CAB009368" Supported Supported Nucleoplasm,Cytosol NA NA 670000 "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 8 Nucleoplasm Cytosol "CAB009368: , HPA008999: " "unprognostic (2.24e-1)" "unprognostic (8.36e-2)" "unprognostic (1.59e-3)" "unprognostic (3.00e-3)" "unprognostic (9.39e-2)" "unprognostic (2.48e-1)" "unprognostic (6.14e-2)" "unprognostic (3.02e-3)" "potential prognostic unfavorable (9.35e-5)" "unprognostic (9.99e-2)" "validated prognostic favorable (2.85e-10)" "validated prognostic favorable (1.12e-4)" "unprognostic (5.33e-2)" "unprognostic (1.33e-1)" "unprognostic (3.07e-1)" "unprognostic (1.83e-2)" "unprognostic (8.40e-3)" "unprognostic (2.33e-2)" "unprognostic (9.46e-2)" "unprognostic (1.58e-2)" "potential prognostic unfavorable (6.66e-4)" "potential prognostic unfavorable (2.03e-5)" "unprognostic (6.31e-2)" "unprognostic (2.10e-1)" "unprognostic (2.04e-1)" "unprognostic (1.14e-1)" "unprognostic (1.30e-1)" "unprognostic (1.88e-1)" "unprognostic (1.71e-1)" "unprognostic (1.18e-2)" "unprognostic (2.34e-2)" EFNB3 "EPLG8, LERK-8" ENSG00000108947 "Ephrin B3" Q15768 17 7705202-7711372 "Cancer-related genes, Predicted membrane proteins" "Differentiation, Host-virus interaction, Neurogenesis" "Developmental protein, Host cell receptor for virus entry, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 41.5" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 11.9;Brain inhibitory neurons: 19.1;Early spermatids: 9.4;Ependymal cells: 22.0;Epididymal efferent duct ciliated cells: 17.2;Hepatic stellate cells: 12.9;Other brain neurons: 21.6;Pancreatic islet cells: 10.0;Respiratory ciliated cells: 24.4;Retinal amacrine cells: 8.9" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 25.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 17.5" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells, Liver - Hepatic stellate cells, Lung - Respiratory ciliated cells, Prostate - Prostate basal glandular cells, Skin - Outer root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001623 Approved NA NA 5600 "Cluster 78: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" 4 "HPA001623: " "unprognostic (4.83e-3)" "unprognostic (1.31e-2)" "unprognostic (1.27e-1)" "unprognostic (4.32e-2)" "unprognostic (6.23e-2)" "unprognostic (2.46e-1)" "unprognostic (6.66e-2)" "unprognostic (1.19e-2)" "unprognostic (7.46e-2)" "unprognostic (1.78e-1)" "unprognostic (3.74e-1)" "unprognostic (5.93e-2)" "unprognostic (2.83e-1)" "unprognostic (5.98e-2)" "unprognostic (7.46e-2)" "unprognostic (2.87e-1)" "unprognostic (2.54e-3)" "unprognostic (2.14e-1)" "unprognostic (1.88e-1)" "unprognostic (4.53e-2)" "unprognostic (1.52e-1)" "unprognostic (1.71e-2)" "unprognostic (2.05e-1)" EFR3A KIAA0143 ENSG00000132294 "EFR3 homolog A" Q14156 8 131904093-132013642 "Disease related genes, Predicted intracellular proteins" "Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 112.6" "Cell type enhanced" "Detected in all" "Retinal bipolar cells: 680.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022859, HPA023092, HPA023402" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 42: Retina - Visual perception" "Cluster 24: Neurons - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 5 "Plasma membrane, Cytosol" "HPA022859: , HPA023092: , HPA023402: " "unprognostic (1.65e-1)" "unprognostic (4.36e-2)" "unprognostic (1.30e-1)" "unprognostic (6.48e-3)" "unprognostic (2.84e-1)" "unprognostic (6.63e-2)" "unprognostic (1.19e-1)" "unprognostic (2.08e-1)" "unprognostic (2.48e-1)" "unprognostic (1.13e-3)" "potential prognostic favorable (3.24e-4)" "unprognostic (2.10e-2)" "unprognostic (1.61e-1)" "unprognostic (8.75e-2)" "unprognostic (1.08e-1)" "unprognostic (8.06e-2)" "unprognostic (4.15e-2)" "unprognostic (3.08e-1)" "unprognostic (8.76e-2)" "unprognostic (6.58e-2)" "unprognostic (5.48e-3)" "unprognostic (4.64e-3)" "unprognostic (1.42e-2)" "unprognostic (1.60e-1)" "unprognostic (1.18e-1)" "unprognostic (3.24e-1)" "unprognostic (2.35e-1)" "unprognostic (8.77e-2)" "unprognostic (1.84e-1)" "unprognostic (1.20e-1)" "unprognostic (3.74e-3)" EFR3B "FLJ37871, KIAA0953" ENSG00000084710 "EFR3 homolog B" Q9Y2G0 2 25042076-25159135 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.5;skeletal muscle: 18.6" "Cell type enhanced" "Detected in many" "Astrocytes: 207.7;Bergmann glia: 92.7;Brain excitatory neurons: 135.0;Brain inhibitory neurons: 164.0;Corticotrophs: 100.3;Lactotrophs: 125.1;Retinal ganglion cells: 239.5;Retinal pigment epithelial cells: 537.1;Thyrotrophs: 121.5" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 10.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.3" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Lung - Alveolar cells type 1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038089, HPA071831" Uncertain Supported "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 32: Basophils - Transcription" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 24: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" 4 "Plasma membrane" "Actin filaments, Cytosol" "HPA038089: , HPA071831: " "unprognostic (6.40e-2)" "unprognostic (4.57e-1)" "unprognostic (1.65e-2)" "unprognostic (2.89e-1)" "unprognostic (2.10e-2)" "unprognostic (1.52e-2)" "unprognostic (7.70e-2)" "unprognostic (2.60e-2)" "potential prognostic favorable (1.07e-5)" "unprognostic (1.82e-1)" "unprognostic (3.12e-1)" "unprognostic (8.48e-2)" "unprognostic (7.41e-2)" "unprognostic (1.53e-1)" "unprognostic (2.60e-2)" EFS "CASS3, EFS1, EFS2, HEFS, SIN" ENSG00000100842 "Embryonal Fyn-associated substrate" O43281 14 23356403-23365752 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bergmann glia: 36.2;Breast lactating cells: 35.4;Esophageal apical cells: 33.2;Esophageal suprabasal cells: 39.9;Hepatic stellate cells: 38.7;Oligodendrocyte progenitor cells: 46.6;Oligodendrocytes: 63.5;Schwann cells: 50.4" "Cell type enhanced" "Detected in many" "oligodendrocyte: 79.4;oligodendrocyte precursor cell: 50.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Testis - Peritubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001581, HPA001790" Approved Uncertain Nucleoplasm,Cytosol No NA "Cluster 68: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 85: Squamous epithelial cells - Keratinization" 16 Nucleoplasm Cytosol "HPA001581: , HPA001790: " "unprognostic (1.21e-1)" "unprognostic (2.26e-2)" "unprognostic (3.32e-2)" "unprognostic (2.55e-2)" "unprognostic (1.44e-2)" "unprognostic (2.77e-1)" "unprognostic (8.75e-2)" "potential prognostic favorable (2.02e-4)" "unprognostic (7.53e-2)" "unprognostic (5.54e-3)" "unprognostic (1.04e-1)" "unprognostic (5.11e-2)" "unprognostic (1.68e-1)" "unprognostic (4.02e-2)" "unprognostic (1.03e-1)" "unprognostic (2.37e-2)" "unprognostic (2.62e-2)" "unprognostic (8.46e-2)" "unprognostic (1.54e-1)" "unprognostic (3.11e-1)" "unprognostic (2.19e-1)" "unprognostic (2.12e-2)" "unprognostic (2.05e-1)" "unprognostic (1.53e-1)" "unprognostic (2.95e-2)" "unprognostic (7.58e-3)" "unprognostic (1.23e-1)" "unprognostic (3.58e-1)" "unprognostic (1.47e-1)" EFTUD2 "SNRNP116, Snrp116, Snu114, U5-116KD" ENSG00000108883 "Elongation factor Tu GTP binding domain containing 2" Q15029 17 44849948-44899445 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022021 Supported Supported Nucleoplasm,Vesicles,Cytosol NA NA 190000 "Cluster 29: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 17: Non-specific - RNA processing" 326 Nucleoplasm "Vesicles, Cytosol" "HPA022021: " "unprognostic (8.50e-3)" "potential prognostic unfavorable (7.91e-4)" "unprognostic (1.09e-1)" "unprognostic (1.89e-1)" "unprognostic (3.31e-3)" "unprognostic (2.54e-1)" "unprognostic (1.48e-1)" "unprognostic (2.43e-3)" "unprognostic (3.24e-2)" "potential prognostic unfavorable (3.75e-4)" "potential prognostic favorable (4.93e-5)" "unprognostic (4.89e-2)" "unprognostic (1.38e-1)" "validated prognostic unfavorable (3.43e-5)" "validated prognostic unfavorable (7.07e-5)" "unprognostic (4.76e-3)" "unprognostic (2.99e-3)" "unprognostic (1.15e-1)" "unprognostic (5.83e-3)" "unprognostic (1.09e-1)" "unprognostic (1.77e-1)" "unprognostic (4.45e-2)" "unprognostic (3.11e-3)" "unprognostic (2.13e-1)" "unprognostic (1.17e-2)" "unprognostic (4.20e-2)" "unprognostic (1.57e-1)" "unprognostic (1.01e-1)" "unprognostic (2.68e-1)" "unprognostic (2.04e-1)" "unprognostic (3.04e-2)" EGF ENSG00000138798 "Epidermal growth factor" P01133 4 109912883-110013766 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins" "Growth factor" "Cancer-related genes, Disease variant, FDA approved drug targets, Primary hypomagnesemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "kidney: 102.9;pancreas: 84.4;skeletal muscle: 26.0" "Cell type enriched" "Detected in many" 4 "Distal convoluted tubule cells: 4773.2" "Cell type enhanced" "Detected in many" "hippocampal CA4: 46.4;lower rhombic lip: 44.0" "Cancer enriched" "Detected in many" 9 "Kidney Chromophobe (TCGA): 27.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Exocrine glandular cells, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" NA NA 980000 "Cluster 72: Kidney - Transmembrane transport" "Cluster 39: Astrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 6 "unprognostic (5.33e-3)" "unprognostic (8.70e-2)" "unprognostic (2.56e-2)" "unprognostic (6.29e-2)" "unprognostic (4.94e-2)" "unprognostic (1.01e-2)" "unprognostic (1.52e-2)" "unprognostic (5.41e-3)" "unprognostic (4.37e-3)" "unprognostic (1.19e-1)" "unprognostic (2.50e-2)" "unprognostic (3.45e-1)" "unprognostic (1.81e-1)" "potential prognostic unfavorable (8.39e-4)" "unprognostic (1.89e-1)" "unprognostic (9.49e-2)" EGFL6 MAEG ENSG00000198759 "EGF like domain multiple 6" Q8IUX8 X 13569601-13633575 "Predicted secreted proteins" "Cell adhesion, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 25 "placenta: 605.7" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 28.6;Esophageal suprabasal cells: 36.9;Fibroblasts: 143.3;Oocytes: 64.5;Parietal cells: 40.7;Pericytes: 186.9;Respiratory deuterosomal cells: 20.7;Respiratory secretory cells: 31.2" "Cell type enhanced" "Detected in some" "CGE interneuron: 7.2;LAMP5-LHX6 and Chandelier: 26.3" "Cancer enhanced" "Detected in many" "Lung Squamous Cell Carcinoma (TCGA): 20.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Rhabdoid: 24.7" "Kidney - Ascending Loop of Henle cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA001838 Enhanced "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 108: Fibroblasts - ECM organization" 4 "HPA001838: " "unprognostic (2.21e-3)" "unprognostic (1.76e-1)" "unprognostic (1.49e-1)" "unprognostic (2.66e-2)" "unprognostic (9.96e-2)" "unprognostic (9.50e-2)" "unprognostic (6.39e-2)" "unprognostic (3.67e-3)" "unprognostic (1.69e-2)" "validated prognostic unfavorable (9.56e-4)" "validated prognostic unfavorable (5.14e-4)" "unprognostic (2.05e-1)" "unprognostic (2.96e-2)" "unprognostic (1.07e-1)" "unprognostic (1.91e-1)" "unprognostic (2.54e-2)" "unprognostic (2.88e-1)" "unprognostic (2.50e-3)" "unprognostic (2.08e-2)" "unprognostic (9.03e-2)" "unprognostic (6.12e-3)" "unprognostic (1.60e-2)" "unprognostic (4.64e-2)" "unprognostic (3.42e-2)" "unprognostic (1.86e-1)" EGFL7 ZNEU1 ENSG00000172889 "EGF like domain multiple 7" Q9UHF1 9 136658856-136672678 "Predicted secreted proteins" "Angiogenesis, Cell adhesion, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 191.6;Epididymal principal cells: 237.0;Hematopoietic stem cells: 184.9;Hofbauer cells: 665.8;Lymphatic endothelial cells: 381.1;Megakaryocytes: 160.7;Pancreatic islet cells: 119.7;Platelets: 382.4;Undifferentiated spermatogonia: 138.2;Vascular endothelial cells: 574.3" "Cell type enriched" "Detected in many" 13 "endothelial cell: 586.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 2.1;eosinophil: 3.5;intermediate monocyte: 6.2;non-classical monocyte: 5.6;plasmacytoid DC: 5.9" "Group enriched" "Detected in many" 20 "dendritic cells: 5.9;granulocytes: 3.5;monocytes: 6.2" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050716 Approved "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 12 "HPA050716: " "unprognostic (1.58e-1)" "unprognostic (3.79e-2)" "unprognostic (2.78e-2)" "unprognostic (3.82e-2)" "unprognostic (3.42e-3)" "unprognostic (1.37e-1)" "unprognostic (4.05e-2)" "unprognostic (2.86e-1)" "unprognostic (7.73e-3)" "unprognostic (6.44e-3)" "unprognostic (5.61e-2)" "unprognostic (2.35e-3)" "unprognostic (4.77e-3)" "unprognostic (2.49e-1)" "unprognostic (6.55e-2)" "unprognostic (2.56e-2)" "unprognostic (4.09e-1)" "unprognostic (5.86e-2)" "unprognostic (1.65e-1)" "unprognostic (1.33e-1)" "unprognostic (3.09e-1)" "potential prognostic favorable (4.70e-4)" "unprognostic (2.45e-2)" "unprognostic (3.11e-2)" "unprognostic (2.50e-2)" "unprognostic (2.10e-1)" "unprognostic (2.91e-3)" "unprognostic (3.64e-2)" "unprognostic (1.93e-1)" "unprognostic (1.27e-2)" "unprognostic (1.31e-2)" EGFL8 "C6orf8, NG3" ENSG00000241404 "EGF like domain multiple 8" Q99944 6 32164595-32168281 "Metabolic proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 15.0;Bergmann glia: 14.4;Brain excitatory neurons: 5.6;Brain inhibitory neurons: 4.7;Choroid plexus epithelial cells: 10.4;Ependymal cells: 13.1;Microglia: 4.9;Oligodendrocyte progenitor cells: 8.6;Oligodendrocytes: 9.5;Other brain neurons: 3.4;Vascular endothelial cells: 3.9" "Cell type enriched" "Detected in all" 4 "endothelial cell: 130.5" "Cancer enriched" "Detected in some" 8 "Skin Cutaneous Melanoma (TCGA): 24.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 8 "skin cancer: 10.1" "Colon - Enteric glia cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA061173 Uncertain Approved "Nuclear speckles,Vesicles" "Secreted - unknown location" "No annotated function" NA NA "Cluster 64: Non-specific - Transcription" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 69: Skin cancer - ECM organization" "Cluster 104: Brain endothelial cells - Blood brain barrier" 40 Vesicles "Nuclear speckles" "HPA061173: " "unprognostic (1.52e-1)" "unprognostic (9.71e-2)" "unprognostic (3.06e-2)" "unprognostic (5.37e-2)" "unprognostic (2.75e-2)" "unprognostic (5.05e-2)" "unprognostic (2.77e-1)" "unprognostic (1.13e-3)" "unprognostic (3.03e-3)" "unprognostic (3.93e-2)" "unprognostic (2.41e-2)" "unprognostic (3.79e-1)" EGFLAM "AGRINL, AGRNL, FLJ39155, PIKA" ENSG00000164318 "EGF like, fibronectin type III and laminin G domains" Q63HQ2 5 38258409-38465480 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 113.3" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 329.7;Cone photoreceptor cells: 1159.3;Leydig cells: 161.1;Pericytes: 330.1;Rod photoreceptor cells: 369.0" "Cell type enhanced" "Detected in many" "fibroblast: 23.2;lower rhombic lip: 58.0;vascular associated smooth muscle cell: 22.7" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 26.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 37.6" "Prostate - Fibroblasts, Stomach - Fibroblasts, Testis - Late spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA066577 Approved "Secreted - unknown location" "No annotated function" NA NA "Cluster 63: Non-specific - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 110: Mural cells - ECM organization" 1 "HPA066577: " "unprognostic (4.99e-2)" "unprognostic (6.03e-2)" "unprognostic (5.35e-1)" "unprognostic (4.34e-2)" "unprognostic (1.50e-1)" "unprognostic (2.80e-1)" "unprognostic (1.00e-2)" "unprognostic (1.79e-2)" "unprognostic (4.68e-2)" "unprognostic (5.43e-2)" "unprognostic (2.14e-2)" "unprognostic (4.65e-3)" "potential prognostic unfavorable (6.62e-4)" "unprognostic (2.80e-1)" "unprognostic (1.14e-1)" "unprognostic (2.37e-1)" "unprognostic (1.74e-2)" "unprognostic (2.16e-1)" "unprognostic (2.67e-2)" "unprognostic (1.09e-2)" "unprognostic (1.13e-1)" "unprognostic (3.24e-1)" "unprognostic (3.28e-2)" "unprognostic (8.06e-2)" "unprognostic (1.11e-2)" "unprognostic (5.69e-2)" "unprognostic (1.13e-2)" "potential prognostic unfavorable (2.68e-4)" "unprognostic (2.30e-1)" "unprognostic (9.72e-2)" "unprognostic (2.63e-2)" EGFR "ERBB, ERBB1, ERRP" ENSG00000146648 "Epidermal growth factor receptor" P00533 7 55019017-55211628 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins, Transporters" "Host-virus interaction" "Developmental protein, Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 61.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1190.3;Fibro-adipogenic progenitors: 1097.7;Myosatellite cells: 789.2;Respiratory basal cells: 935.5;Syncytiotrophoblasts: 1481.8" "Cell type enhanced" "Detected in many" "astrocyte: 363.8;Bergmann glia: 419.5" "Cancer enriched" "Detected in all" 4 "Glioblastoma Multiforme (TCGA): 324.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000035, HPA001200, HPA018530, CAB068186, CAB073534, CAB080313, CAB080314, CAB080473, CAB080474, CAB080475, CAB080506, CAB080507, CAB080508, CAB080509, CAB080510, CAB080511, CAB080513" Enhanced Supported "Golgi apparatus,Plasma membrane,Cell Junctions,Primary cilium,Basal body,Mid piece,Principal piece,End piece" "Secreted to blood" Receptor NA NA 4740000 19000000 "Cluster 11: Esophagus - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 108: Fibroblasts - ECM organization" 926 "Golgi apparatus, Plasma membrane" "Cell Junctions, Primary cilium, Basal body, Mid piece, Principal piece, End piece" "CAB000035: , CAB068186: , CAB073534: , CAB080313: , CAB080314: , CAB080473: , CAB080474: , CAB080475: , CAB080506: , CAB080507: , CAB080508: , CAB080509: , CAB080510: , CAB080511: , CAB080513: , HPA001200: , HPA018530: " "unprognostic (7.14e-2)" "unprognostic (2.28e-2)" "unprognostic (9.66e-2)" "unprognostic (2.14e-3)" "unprognostic (9.48e-2)" "unprognostic (9.42e-2)" "unprognostic (1.44e-1)" "unprognostic (2.07e-2)" "unprognostic (3.73e-2)" "unprognostic (2.68e-3)" "potential prognostic favorable (8.23e-5)" "unprognostic (1.24e-2)" "unprognostic (1.11e-1)" "unprognostic (1.35e-1)" "unprognostic (1.01e-2)" "unprognostic (4.78e-2)" "unprognostic (1.38e-1)" "unprognostic (6.90e-2)" "unprognostic (2.25e-1)" "unprognostic (3.35e-3)" "unprognostic (2.91e-1)" "unprognostic (5.73e-3)" "potential prognostic unfavorable (4.42e-5)" "unprognostic (1.11e-1)" "unprognostic (3.51e-2)" "unprognostic (1.84e-1)" "unprognostic (1.92e-2)" "unprognostic (4.08e-2)" "unprognostic (1.52e-1)" "unprognostic (4.14e-2)" "unprognostic (9.81e-2)" EGLN1 "C1orf12, HIFPH2, PHD2, SM-20, ZMYND6" ENSG00000135766 "Egl-9 family hypoxia inducible factor 1" Q9GZT9 1 231363751-231422287 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Congenital erythrocytosis, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "skeletal muscle: 396.2;tongue: 143.2" "Cell type enhanced" "Detected in many" "Astrocytes: 54.5;Bergmann glia: 69.4;Brain excitatory neurons: 64.5;Brain inhibitory neurons: 65.0;Choroid plexus epithelial cells: 88.8;Distal convoluted tubule cells: 94.6;Loop of henle epithelial cells: 71.3;Microglia: 95.8;Oligodendrocyte progenitor cells: 71.0;Oligodendrocytes: 62.3;Other brain neurons: 49.6;Papillary tip epithelial cells: 53.4;Podocytes: 57.6;Proximal tubule cells: 72.1;Renal collecting duct intercalated cells: 168.2;Renal collecting duct principal cells: 81.8;Renal connecting tubule cells: 68.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 29.2" "Lineage enriched" "Detected in many" 15 "granulocytes: 29.2" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022129 Approved Supported Vesicles,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 7: Non-specific - Ribosome" "Cluster 45: Non-specific - Nuclear processes" "Cluster 102: Non-specific - Mixed function" 30 Cytosol Vesicles "HPA022129: " "unprognostic (2.79e-2)" "unprognostic (5.90e-2)" "unprognostic (1.83e-1)" "unprognostic (4.35e-3)" "unprognostic (4.38e-2)" "unprognostic (1.16e-2)" "unprognostic (3.39e-1)" "unprognostic (1.56e-1)" "unprognostic (2.06e-1)" "unprognostic (1.97e-1)" "potential prognostic favorable (8.41e-8)" "unprognostic (1.39e-2)" "unprognostic (1.10e-1)" "unprognostic (6.51e-2)" "unprognostic (1.96e-1)" "potential prognostic unfavorable (5.96e-5)" "unprognostic (5.67e-2)" "unprognostic (3.92e-1)" "unprognostic (5.72e-2)" "unprognostic (2.29e-1)" "unprognostic (1.03e-2)" "unprognostic (4.79e-2)" "unprognostic (2.36e-1)" "unprognostic (2.81e-1)" "unprognostic (1.18e-1)" "unprognostic (9.51e-3)" "unprognostic (2.89e-1)" "unprognostic (1.07e-1)" "unprognostic (2.63e-1)" "unprognostic (2.76e-2)" "unprognostic (2.93e-1)" EGLN2 "HIFPH1, PHD1" ENSG00000269858 "Egl-9 family hypoxia inducible factor 2" Q96KS0 19 40798996-40808434 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 223.9" "Cell type enhanced" "Detected in some" "Early spermatids: 1.0;Late primary spermatocytes: 2.1;Platelets: 2.8" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056649 Supported Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 67: Testis - Mixed function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 98: Neurons - Neurotransmission & signaling" 8 Nucleoplasm "HPA056649: " "unprognostic (3.36e-2)" "unprognostic (4.74e-2)" "unprognostic (3.24e-2)" "unprognostic (3.15e-2)" "unprognostic (3.82e-2)" "unprognostic (1.01e-1)" "unprognostic (1.23e-1)" "unprognostic (4.91e-2)" "unprognostic (1.06e-2)" "unprognostic (6.38e-2)" "unprognostic (1.14e-1)" "unprognostic (1.84e-1)" "unprognostic (4.89e-2)" "unprognostic (5.19e-3)" "unprognostic (6.82e-2)" "unprognostic (8.56e-2)" "unprognostic (1.36e-1)" "unprognostic (7.28e-2)" "unprognostic (1.02e-1)" "unprognostic (8.54e-2)" "unprognostic (2.09e-1)" "unprognostic (4.53e-3)" "unprognostic (2.52e-1)" "unprognostic (4.27e-1)" "unprognostic (4.34e-1)" "unprognostic (5.21e-3)" "unprognostic (3.87e-2)" "unprognostic (2.58e-1)" "unprognostic (2.74e-1)" "unprognostic (2.16e-1)" "unprognostic (1.53e-1)" EGLN3 "HIFPH3, PHD3" ENSG00000129521 "Egl-9 family hypoxia inducible factor 3" Q9H6Z9 14 33924227-34462774 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Apoptosis, DNA damage" "Dioxygenase, Oxidoreductase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 101.7;skin 1: 114.3" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 576.3;Extravillous trophoblasts: 263.9;Fallopian tube ciliated cells: 187.2;Melanocytes: 419.4;pDCs: 206.8;Prostatic club cells: 218.7;Respiratory ciliated cells: 239.1;Suprabasal keratinocytes: 191.5;Urothelial cells: 272.4" "Cell type enhanced" "Detected in all" "astrocyte: 202.0" "Cancer enriched" "Detected in all" 5 "Kidney Renal Clear Cell Carcinoma (TCGA): 379.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 10 "plasmacytoid DC: 25.5" "Lineage enriched" "Detected in many" 14 "dendritic cells: 25.5" "Cancer enhanced" "Detected in all" "Kidney cancer: 97.0" "Liver - Vascular endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064895 Supported Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 58: Skin - Keratinization" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 69: Urothelial cells - Basic cellular functions" 56 Cytosol "HPA064895: " "unprognostic (2.03e-1)" "unprognostic (4.41e-2)" "unprognostic (4.70e-1)" "unprognostic (5.28e-3)" "unprognostic (2.99e-1)" "unprognostic (1.23e-1)" "unprognostic (7.91e-2)" "unprognostic (8.97e-3)" "unprognostic (1.58e-2)" "potential prognostic unfavorable (1.45e-5)" "potential prognostic favorable (1.01e-4)" "unprognostic (1.83e-3)" "unprognostic (1.15e-2)" "validated prognostic unfavorable (1.32e-5)" "validated prognostic unfavorable (3.69e-4)" "potential prognostic unfavorable (1.62e-4)" "unprognostic (1.90e-3)" "unprognostic (1.94e-1)" "unprognostic (1.58e-2)" "unprognostic (3.83e-1)" "unprognostic (3.63e-1)" "unprognostic (2.23e-2)" "unprognostic (3.27e-1)" "unprognostic (1.73e-1)" "unprognostic (1.26e-1)" "potential prognostic unfavorable (3.66e-4)" "unprognostic (6.39e-3)" "unprognostic (1.39e-1)" "unprognostic (1.83e-1)" "unprognostic (1.41e-2)" "unprognostic (1.67e-1)" EGR1 "225, AT225, G0S30, KROX-24, NGFI-A, TIS8, ZIF-268" ENSG00000120738 "Early growth response 1" P18146 5 138465479-138469303 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal basal cells: 1777.0;Medullary thymic epithelial cells: 1219.3;Ovarian stromal cells: 1277.4;Thymic myoid cells: 1354.2" "Cell type enhanced" "Detected in many" "vascular associated smooth muscle cell: 81.1" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 273.3" "Immune cell enhanced" "Detected in some" "neutrophil: 7.1" "Group enriched" "Detected in many" 7 "granulocytes: 7.1;monocytes: 3.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019427, HPA029937, HPA029938" Supported Enhanced Nucleoplasm No No "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 75: Ovary - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 16 Nucleoplasm "CAB019427: , HPA029937: , HPA029938: " "unprognostic (2.84e-2)" "unprognostic (7.42e-2)" "unprognostic (5.87e-2)" "unprognostic (4.23e-2)" "unprognostic (1.95e-2)" "unprognostic (2.03e-1)" "unprognostic (1.13e-1)" "unprognostic (5.12e-2)" "unprognostic (2.72e-1)" "unprognostic (2.78e-1)" "potential prognostic favorable (2.64e-5)" "unprognostic (2.32e-2)" "unprognostic (1.38e-1)" "unprognostic (3.24e-1)" "unprognostic (4.45e-3)" "unprognostic (1.04e-1)" "unprognostic (1.22e-1)" "unprognostic (6.23e-2)" "unprognostic (7.02e-2)" "potential prognostic unfavorable (9.26e-4)" "unprognostic (4.08e-1)" "unprognostic (1.46e-1)" "unprognostic (2.54e-1)" "unprognostic (1.69e-2)" "unprognostic (2.63e-1)" "potential prognostic favorable (3.57e-4)" "unprognostic (2.84e-1)" "unprognostic (1.94e-2)" "unprognostic (1.42e-1)" "unprognostic (2.70e-1)" "unprognostic (3.52e-1)" EGR2 KROX20 ENSG00000122877 "Early growth response 2" P11161 10 62811996-62819167 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, DNA-binding, Transferase" "Charcot-Marie-Tooth disease, Dejerine-Sottas syndrome, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 56.3;thyroid gland: 114.5" "Cell type enhanced" "Detected in many" "Breast secretory cells: 115.5;Epididymal basal cells: 78.6;Epididymal principal cells: 453.6" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 3.7" "Cancer enhanced" "Detected in all" "Thyroid Carcinoma (TCGA): 36.0" "Group enriched" "Detected in all" 5 "cerebral cortex: 18.8;hippocampal formation: 11.4" "Group enriched" "Detected in some" 5 "intermediate monocyte: 2.3;non-classical monocyte: 2.2" "Lineage enriched" "Detected in single" 5 "monocytes: 2.3" "Cancer enhanced" "Detected in many" "lymphoma: 11.2" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA031165, HPA065377" Approved Nucleoplasm NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 22: Epididymis - Mixed function" "Cluster 29: Forebrain - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 3 Nucleoplasm "HPA031165: , HPA065377: " "unprognostic (3.32e-1)" "potential prognostic favorable (7.46e-4)" "unprognostic (4.50e-2)" "unprognostic (6.62e-2)" "unprognostic (5.51e-2)" "unprognostic (1.30e-2)" "unprognostic (1.84e-1)" "unprognostic (8.89e-3)" "unprognostic (2.39e-1)" "unprognostic (2.81e-1)" "unprognostic (1.24e-1)" "unprognostic (9.22e-2)" "unprognostic (7.14e-2)" "unprognostic (2.23e-1)" "potential prognostic favorable (6.35e-4)" "unprognostic (1.70e-2)" "unprognostic (6.16e-2)" "unprognostic (2.85e-2)" "unprognostic (4.33e-1)" "unprognostic (1.41e-2)" "unprognostic (2.31e-1)" "unprognostic (7.25e-2)" "unprognostic (2.10e-1)" "unprognostic (1.86e-1)" "unprognostic (1.03e-1)" "unprognostic (3.63e-3)" "unprognostic (1.47e-1)" "unprognostic (1.81e-1)" "unprognostic (1.37e-2)" "unprognostic (1.04e-1)" "unprognostic (2.55e-2)" EGR3 PILOT ENSG00000179388 "Early growth response 3" Q06889 8 22687659-22693480 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 41.7" "Cell type enhanced" "Detected in many" "Breast secretory cells: 211.9;Endometrial glandular cells: 122.5;Endometrial luminal cells: 144.2;Endometrial secretory cells: 120.9;Epididymal basal cells: 119.6;Epididymal efferent duct absorptive cells: 81.7;Fallopian secretory cells: 83.1;Mast cells: 83.9;Neuroendocrine cells: 121.4;Neutrophils: 291.0;Salivary myoepithelial cells: 113.4" "Cell type enhanced" "Detected in many" "upper-layer intratelencephalic: 19.6" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "cerebral cortex: 111.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 12.3" "Skeletal muscle - Fibroblasts, Skin - Keratinocyte (granular), Testis - Late spermatids" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 9 "amygdala: 25.5;basal ganglia: 59.0;cerebral cortex: 56.6;hippocampal formation: 49.0;olfactory bulb: 39.1" "HPA006206, CAB009373" Uncertain Uncertain Nucleoplasm,Vesicles NA NA "Cluster 58: Skin - Keratinization" "Cluster 51: Neurons - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" Nucleoplasm Vesicles "CAB009373: , HPA006206: " "unprognostic (2.02e-2)" "potential prognostic favorable (4.12e-4)" "unprognostic (1.72e-3)" "unprognostic (1.58e-1)" "unprognostic (1.08e-1)" "unprognostic (1.31e-2)" "unprognostic (5.10e-2)" "unprognostic (1.76e-1)" "unprognostic (2.78e-2)" "unprognostic (4.89e-3)" "unprognostic (8.73e-3)" "unprognostic (8.51e-3)" "unprognostic (6.61e-3)" "unprognostic (3.27e-2)" "unprognostic (7.18e-2)" "unprognostic (8.48e-2)" "unprognostic (2.42e-1)" "unprognostic (1.99e-1)" "unprognostic (1.62e-2)" "unprognostic (6.09e-2)" "unprognostic (7.69e-2)" "unprognostic (1.29e-1)" "unprognostic (1.02e-1)" "unprognostic (2.47e-2)" "unprognostic (2.80e-3)" "unprognostic (7.49e-3)" "unprognostic (7.64e-3)" "unprognostic (1.34e-1)" "unprognostic (9.78e-3)" "unprognostic (2.48e-1)" EGR4 "NGFI-C, PAT133" ENSG00000135625 "Early growth response 4" Q05215 2 73290929-73293701 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 19.1" "Cell type enhanced" "Detected in some" "Breast secretory cells: 25.3;Endometrial glandular cells: 21.2;Endometrial secretory cells: 15.9;Epididymal basal cells: 18.1;Granulosa cells: 58.4;Neuroendocrine cells: 48.4;Pancreatic islet cells: 9.9;Undifferentiated spermatogonia: 23.2" "Cell type enhanced" "Detected in many" "medium spiny neuron: 16.3" "Not detected" "Not detected" "Group enriched" "Detected in all" 5 "cerebellum: 68.0;cerebral cortex: 113.4;hippocampal formation: 48.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Neuroblastoma: 1.0" "Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA028983 Enhanced NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 15: Non-specific - Transcription" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" 1 "HPA028983: " EHBP1 "KIAA0903, NACSIN" ENSG00000115504 "EH domain binding protein 1" Q8NDI1 2 62673851-63046487 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 1746.1;Schwann cells: 1537.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035468, HPA035469" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 75: Ovary - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 89: Adipocytes - Lipid metabolism" 5 "Plasma membrane" Cytosol "HPA035468: , HPA035469: " "unprognostic (3.78e-2)" "unprognostic (1.10e-1)" "unprognostic (2.53e-1)" "unprognostic (6.34e-3)" "unprognostic (2.50e-1)" "unprognostic (1.83e-1)" "unprognostic (5.47e-2)" "unprognostic (2.76e-2)" "unprognostic (3.29e-2)" "unprognostic (6.84e-2)" "potential prognostic favorable (1.95e-7)" "unprognostic (5.73e-3)" "unprognostic (1.96e-1)" "unprognostic (1.61e-1)" "unprognostic (1.40e-1)" "potential prognostic unfavorable (1.52e-4)" "unprognostic (2.23e-1)" "unprognostic (1.31e-1)" "unprognostic (3.67e-2)" "unprognostic (1.90e-2)" "unprognostic (1.24e-1)" "unprognostic (2.15e-3)" "unprognostic (1.93e-3)" "unprognostic (1.20e-1)" "unprognostic (1.65e-1)" "unprognostic (4.03e-2)" "unprognostic (3.04e-1)" "unprognostic (3.67e-2)" "unprognostic (1.57e-1)" "unprognostic (2.85e-2)" "unprognostic (1.04e-2)" EHBP1L1 "DKFZp762C186, TANGERIN" ENSG00000173442 "EH domain binding protein 1 like 1" Q8N3D4 11 65576046-65592650 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 239.6" "Cell type enhanced" "Detected in many" "Foveolar cells: 142.2;Kupffer cells: 127.1;monocytes: 132.7;Myonuclei: 211.0;Neutrophils: 171.9;Thymic myoid cells: 103.3" "Group enriched" "Detected in many" 4 "central nervous system macrophage: 71.9;endothelial cell: 32.6;ependymal cell: 88.8;fibroblast: 31.6;leukocyte: 78.4;pericyte: 47.0;vascular associated smooth muscle cell: 112.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039479, HPA073476" Enhanced Approved "Vesicles,Plasma membrane" NA NA 91000 "Cluster 25: Non-specific - Basic cellular processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 7 "Vesicles, Plasma membrane" "HPA039479: , HPA073476: " "unprognostic (3.80e-2)" "unprognostic (5.25e-2)" "unprognostic (5.59e-2)" "unprognostic (9.65e-3)" "unprognostic (2.77e-1)" "unprognostic (2.39e-1)" "unprognostic (1.37e-1)" "unprognostic (6.76e-2)" "unprognostic (1.72e-1)" "potential prognostic unfavorable (4.42e-4)" "unprognostic (7.25e-3)" "unprognostic (2.70e-1)" "unprognostic (7.50e-2)" "potential prognostic unfavorable (2.92e-5)" "unprognostic (5.40e-1)" "unprognostic (3.29e-1)" "unprognostic (9.56e-3)" "unprognostic (1.41e-1)" "unprognostic (4.29e-1)" "unprognostic (4.08e-2)" "unprognostic (5.62e-2)" "unprognostic (2.73e-2)" "unprognostic (7.17e-2)" "unprognostic (4.08e-2)" "unprognostic (7.95e-2)" "potential prognostic favorable (2.30e-4)" "unprognostic (1.76e-1)" "unprognostic (1.68e-2)" "unprognostic (4.98e-2)" "unprognostic (5.43e-2)" "unprognostic (1.25e-1)" EHD1 "FLJ42622, FLJ44618, H-PAST, HPAST1, PAST1" ENSG00000110047 "EH domain containing 1" Q9H4M9 11 64851642-64888296 "Plasma proteins, Predicted intracellular proteins, Transporters" "Cilium biogenesis/degradation, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 143.0;testis: 148.3" "Group enriched" "Detected in many" 5 "Early spermatids: 1211.5;Late spermatids: 3099.1;Neutrophils: 1042.5" "Cell type enhanced" "Detected in all" "leukocyte: 56.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Stomach - Fibroblasts, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049890, HPA049986, HPA066751, HPA067747" Approved Supported "Plasma membrane,Primary cilium,Primary cilium transition zone" NA NA 6100000 "Cluster 7: Non-specific - Innate immune response" "Cluster 39: Testis - Nuclear processes" "Cluster 25: Non-specific - Transcription" "Cluster 55: Lymphoma - Immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 46 "Plasma membrane" "Primary cilium, Primary cilium transition zone" "HPA049890: , HPA049986: , HPA066751: , HPA067747: " "unprognostic (2.37e-1)" "unprognostic (1.86e-1)" "unprognostic (2.83e-3)" "unprognostic (1.60e-2)" "unprognostic (1.21e-1)" "unprognostic (8.89e-2)" "unprognostic (2.12e-1)" "unprognostic (1.09e-2)" "unprognostic (3.00e-1)" "unprognostic (3.57e-3)" "potential prognostic favorable (2.48e-6)" "unprognostic (7.85e-2)" "unprognostic (4.58e-2)" "potential prognostic unfavorable (3.82e-8)" "unprognostic (3.20e-2)" "unprognostic (6.10e-2)" "potential prognostic unfavorable (9.09e-4)" "unprognostic (1.86e-3)" "unprognostic (2.79e-1)" "unprognostic (2.02e-2)" "unprognostic (4.69e-1)" "potential prognostic unfavorable (7.67e-4)" "unprognostic (1.66e-1)" "unprognostic (1.20e-1)" "unprognostic (6.53e-2)" "unprognostic (8.27e-2)" "unprognostic (2.10e-2)" "unprognostic (2.64e-1)" "unprognostic (4.98e-2)" "unprognostic (5.34e-2)" "unprognostic (2.08e-1)" EHD2 PAST2 ENSG00000024422 "EH domain containing 2" Q9NZN4 19 47713422-47743134 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 246.8;Decidual stromal cells: 129.5;Fibroblasts: 70.6;Hepatic stellate cells: 135.6;Leydig cells: 94.2;Lymphatic endothelial cells: 99.3;Pericytes: 179.2;Peritubular myoid cells: 101.4;Vascular endothelial cells: 72.1;Vascular smooth muscle cells: 164.0" "Group enriched" "Detected in many" 5 "pericyte: 142.0;vascular associated smooth muscle cell: 126.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Endothelial cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047394, HPA049890, HPA049986, HPA066751" Approved Supported "Plasma membrane,Primary cilium,Primary cilium transition zone" NA NA 740000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 19: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 110: Mural cells - ECM organization" 4 "Plasma membrane" "Primary cilium, Primary cilium transition zone" "HPA047394: , HPA049890: , HPA049986: , HPA066751: " "unprognostic (1.87e-1)" "unprognostic (1.21e-1)" "unprognostic (1.18e-1)" "unprognostic (7.23e-3)" "unprognostic (2.27e-2)" "unprognostic (5.12e-2)" "unprognostic (6.52e-2)" "potential prognostic unfavorable (1.88e-4)" "unprognostic (2.01e-2)" "unprognostic (2.71e-2)" "potential prognostic favorable (1.59e-4)" "unprognostic (3.81e-2)" "unprognostic (8.37e-2)" "unprognostic (1.40e-2)" "unprognostic (1.49e-1)" "unprognostic (1.78e-2)" "unprognostic (3.16e-2)" "unprognostic (1.28e-2)" "unprognostic (3.80e-3)" "unprognostic (1.40e-3)" "unprognostic (2.05e-1)" "unprognostic (7.77e-3)" "unprognostic (1.06e-2)" "unprognostic (7.60e-2)" "unprognostic (1.73e-2)" "unprognostic (5.22e-2)" "unprognostic (4.28e-2)" "unprognostic (7.65e-3)" "unprognostic (7.03e-2)" "unprognostic (5.73e-2)" "unprognostic (1.30e-1)" EHD3 PAST3 ENSG00000013016 "EH domain containing 3" Q9NZN3 2 31234152-31269451 "Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 41.0;esophagus: 40.9" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 331.5;Esophageal suprabasal cells: 44.7;Megakaryocytes: 105.1;Ocular epithelial cells: 67.8;Oligodendrocyte progenitor cells: 58.5;Platelets: 273.4;Syncytiotrophoblasts: 88.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "memory B-cell: 20.9;naive B-cell: 5.6" "Lineage enriched" "Detected in many" 7 "B-cells: 20.9" "Low cancer specificity" "Detected in many" "Liver - Sinusoid Endothelial cells, Prostate - Fibroblasts, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049890, HPA049986, HPA066751" Approved Supported "Plasma membrane,Primary cilium,Primary cilium transition zone" NA NA 8800000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 20: Myeloma - Immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 14 "Plasma membrane" "Primary cilium, Primary cilium transition zone" "HPA049890: , HPA049986: , HPA066751: " "unprognostic (1.77e-1)" "unprognostic (7.39e-2)" "unprognostic (2.23e-1)" "unprognostic (7.85e-2)" "unprognostic (2.18e-1)" "unprognostic (5.98e-2)" "unprognostic (1.83e-1)" "unprognostic (6.04e-3)" "unprognostic (1.58e-1)" "unprognostic (2.82e-2)" "validated prognostic favorable (5.01e-6)" "validated prognostic favorable (5.45e-4)" "unprognostic (2.35e-1)" "unprognostic (9.24e-2)" "unprognostic (2.37e-2)" "unprognostic (8.92e-2)" "unprognostic (1.57e-3)" "unprognostic (5.09e-2)" "unprognostic (1.74e-1)" "unprognostic (7.71e-3)" "unprognostic (3.85e-2)" "unprognostic (4.76e-2)" "unprognostic (3.02e-1)" "unprognostic (2.87e-1)" "unprognostic (4.43e-1)" "unprognostic (7.41e-2)" "unprognostic (2.51e-1)" "unprognostic (2.24e-3)" "unprognostic (1.63e-1)" "unprognostic (5.07e-3)" "unprognostic (2.26e-2)" EHD4 PAST4 ENSG00000103966 "EH domain containing 4" Q9H223 15 41895933-41972557 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 305.4;Urothelial cells: 435.9" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 50.4;endothelial cell: 61.1;oligodendrocyte precursor cell: 59.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049890, HPA049986, HPA052729, HPA066751" Approved Uncertain "Plasma membrane,Primary cilium,Primary cilium transition zone" NA NA 510000 "Cluster 33: Non-specific - ATP binding" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 25: Non-specific - Transcription" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 12 "Plasma membrane" "Primary cilium, Primary cilium transition zone" "HPA049890: , HPA049986: , HPA052729: , HPA066751: " "unprognostic (3.79e-2)" "unprognostic (3.76e-2)" "unprognostic (1.81e-2)" "unprognostic (1.74e-2)" "unprognostic (6.29e-3)" "unprognostic (7.01e-3)" "unprognostic (4.76e-3)" "unprognostic (3.85e-3)" "unprognostic (2.21e-2)" "unprognostic (4.68e-2)" "potential prognostic favorable (3.95e-8)" "unprognostic (1.67e-3)" "unprognostic (2.49e-1)" "unprognostic (1.75e-1)" "unprognostic (2.37e-1)" "unprognostic (8.02e-2)" "potential prognostic unfavorable (1.83e-5)" "unprognostic (6.02e-3)" "unprognostic (2.50e-1)" "unprognostic (7.82e-2)" "unprognostic (7.30e-2)" "unprognostic (2.40e-2)" "unprognostic (8.09e-3)" "unprognostic (1.42e-1)" "unprognostic (2.18e-1)" "unprognostic (6.07e-2)" "unprognostic (6.95e-2)" "unprognostic (1.56e-1)" "unprognostic (3.10e-1)" "unprognostic (3.32e-1)" "unprognostic (2.79e-1)" EHF "ESE3, ESEJ" ENSG00000135373 "ETS homologous factor" Q9NZC4 11 34621093-34663288 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 196.3;salivary gland: 270.9" "Cell type enhanced" "Detected in many" "Breast lactating cells: 972.0;Endometrial glandular cells: 877.5;Epididymal basal cells: 875.9;Esophageal apical cells: 3809.7;Esophageal suprabasal cells: 837.8;Lacrimal acinar cells: 2264.6;Ocular epithelial cells: 850.8;Prostatic club cells: 802.7;Prostatic hillock cells: 805.0;Salivary acinar cells: 1080.9" "Cell type enriched" "Detected in some" 5 "ependymal cell: 35.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 11 "myeloid DC: 1.7" "Lineage enriched" "Detected in single" 11 "dendritic cells: 1.7" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Heart muscle - Cardiomyocytes, Liver - Cholangiocytes, Lung - Alveolar cells type 2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA050923, HPA060734" Enhanced Supported "Nucleoplasm,Golgi apparatus" No NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 4 Nucleoplasm "Golgi apparatus" "HPA050923: , HPA060734: " "unprognostic (5.53e-3)" "unprognostic (4.32e-2)" "unprognostic (1.15e-1)" "unprognostic (1.55e-1)" "unprognostic (8.00e-2)" "unprognostic (6.18e-2)" "unprognostic (4.75e-2)" "unprognostic (4.39e-3)" "unprognostic (9.48e-2)" "unprognostic (2.23e-3)" "unprognostic (3.42e-2)" "unprognostic (7.82e-2)" "unprognostic (3.49e-1)" "unprognostic (2.25e-1)" "unprognostic (3.36e-1)" "unprognostic (1.09e-1)" "unprognostic (8.10e-2)" "unprognostic (1.11e-1)" "unprognostic (9.91e-2)" "unprognostic (4.10e-3)" "unprognostic (7.29e-3)" "unprognostic (1.76e-2)" "unprognostic (2.52e-1)" "unprognostic (5.05e-3)" "unprognostic (4.91e-1)" "unprognostic (1.31e-1)" "unprognostic (1.34e-2)" "unprognostic (1.58e-1)" "unprognostic (2.35e-1)" "unprognostic (2.34e-1)" EHHADH ECHD ENSG00000113790 "Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase" Q08426 3 185190624-185281990 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Lyase, Multifunctional enzyme, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 11 "kidney: 134.7;liver: 322.1" "Cell type enhanced" "Detected in many" "Adipocytes: 77.6;Hepatocytes: 401.7;Proximal tubule cells: 271.5;Retinal pigment epithelial cells: 85.3" "Cell type enhanced" "Detected in all" "astrocyte: 41.7;choroid plexus epithelial cell: 42.8" "Group enriched" "Detected in all" 5 "Kidney Renal Clear Cell Carcinoma (TCGA): 56.8;Kidney Renal Papillary Cell Carcinoma (TCGA): 39.8;Liver Hepatocellular Carcinoma (TCGA): 66.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036401, HPA042021" Enhanced NA NA 4500 "Cluster 13: Non-specific - Mitochondria" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 15: Kidney cancer - Membrane components" "Cluster 88: Proximal tubular cells - Transmembrane transport" 105 "HPA036401: , HPA042021: " "unprognostic (1.57e-1)" "unprognostic (1.97e-2)" "unprognostic (1.16e-1)" "unprognostic (4.82e-1)" "unprognostic (2.84e-3)" "unprognostic (1.28e-1)" "unprognostic (2.69e-1)" "unprognostic (1.55e-1)" "unprognostic (9.08e-2)" "unprognostic (4.45e-3)" "potential prognostic favorable (6.09e-10)" "unprognostic (1.09e-3)" "unprognostic (3.05e-2)" "unprognostic (1.76e-3)" "potential prognostic favorable (6.25e-4)" "unprognostic (1.65e-2)" "unprognostic (1.31e-1)" "unprognostic (2.16e-2)" "unprognostic (3.57e-2)" "unprognostic (2.32e-1)" "unprognostic (2.26e-1)" "unprognostic (2.13e-2)" "unprognostic (7.93e-2)" "unprognostic (2.10e-1)" "unprognostic (1.80e-1)" "unprognostic (2.07e-3)" "unprognostic (6.48e-2)" "unprognostic (2.88e-1)" "unprognostic (3.34e-1)" "unprognostic (2.51e-2)" "unprognostic (6.87e-2)" EHMT1 "bA188C12.1, EHMT1-IT1, Eu-HMTase1, FLJ12879, FLJ40292, GLP, KIAA1876, KMT1D" ENSG00000181090 "Euchromatic histone lysine methyltransferase 1" Q9H9B1 9 137618992-137870016 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Chromatin regulator, Methyltransferase, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 516.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060022, HPA074729" Approved Supported "Nucleoplasm,Nuclear bodies" No No "Cluster 21: Neutrophils - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 6: Non-specific - Immune response" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 44: Plasma cells - Antibody production & secretion" 38 "Nucleoplasm, Nuclear bodies" "HPA060022: , HPA074729: " "unprognostic (1.22e-1)" "unprognostic (4.55e-2)" "unprognostic (3.98e-1)" "unprognostic (7.75e-2)" "unprognostic (1.09e-1)" "unprognostic (7.95e-2)" "unprognostic (1.78e-1)" "potential prognostic favorable (2.76e-4)" "unprognostic (3.06e-2)" "unprognostic (3.62e-2)" "unprognostic (1.32e-3)" "unprognostic (9.53e-3)" "unprognostic (1.09e-1)" "unprognostic (1.08e-1)" "unprognostic (7.65e-2)" "unprognostic (1.17e-1)" "potential prognostic unfavorable (7.28e-4)" "unprognostic (2.94e-2)" "unprognostic (3.32e-3)" "unprognostic (1.05e-1)" "unprognostic (2.12e-1)" "unprognostic (2.03e-1)" "unprognostic (1.76e-2)" "unprognostic (6.47e-2)" "unprognostic (3.81e-2)" "unprognostic (1.49e-2)" "unprognostic (1.32e-2)" "unprognostic (7.80e-3)" "unprognostic (4.00e-1)" "unprognostic (8.91e-3)" "unprognostic (3.22e-1)" EHMT2 "BAT8, C6orf30, Em:AF134726.3, G9A, KMT1C, NG36/G9a" ENSG00000204371 "Euchromatic histone lysine methyltransferase 2" Q96KQ7 6 31879759-31897698 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Chromatin regulator, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 32.9;Brain inhibitory neurons: 31.6;Late spermatids: 31.0;Oligodendrocyte progenitor cells: 30.0;Oligodendrocytes: 36.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050550, HPA060259" Supported Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 64: Non-specific - Transcription" "Cluster 19: Astrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 102: Non-specific - Mixed function" 96 "Nucleoplasm, Nuclear speckles" "HPA050550: , HPA060259: " "unprognostic (2.86e-1)" "unprognostic (1.16e-1)" "unprognostic (1.28e-1)" "unprognostic (5.58e-2)" "unprognostic (1.96e-1)" "unprognostic (1.14e-1)" "unprognostic (1.12e-2)" "unprognostic (2.96e-3)" "unprognostic (7.87e-2)" "unprognostic (2.52e-2)" "unprognostic (3.75e-3)" "unprognostic (1.97e-1)" "unprognostic (3.11e-1)" "unprognostic (8.03e-2)" "unprognostic (3.14e-1)" "unprognostic (1.64e-1)" "unprognostic (5.53e-3)" "unprognostic (2.23e-1)" "unprognostic (7.40e-2)" "unprognostic (4.87e-2)" "unprognostic (5.46e-2)" "unprognostic (3.52e-1)" "unprognostic (1.99e-1)" "unprognostic (5.29e-1)" "unprognostic (8.63e-2)" "unprognostic (2.69e-2)" "unprognostic (3.31e-1)" EI24 "EPG4, PIG8, TP53I8" ENSG00000149547 "EI24 autophagy associated transmembrane protein" O14681 11 125569280-125584684 "Cancer-related genes, Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Autophagy" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 434.6" "Cell type enhanced" "Detected in many" "Esophageal suprabasal cells: 284.1;Hepatocytes: 700.0;Oocytes: 345.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Pituitary gland - Corticotropes, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047165, HPA051029" Approved Supported "Endoplasmic reticulum,Golgi apparatus,Cytosol" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 93: Hepatocytes - Bile production & excretion" 31 Cytosol "Endoplasmic reticulum, Golgi apparatus" "HPA047165: , HPA051029: " "unprognostic (2.46e-1)" "potential prognostic unfavorable (9.46e-4)" "unprognostic (8.42e-3)" "unprognostic (3.64e-2)" "unprognostic (7.27e-2)" "unprognostic (1.07e-2)" "unprognostic (5.01e-1)" "unprognostic (6.70e-2)" "unprognostic (1.62e-2)" "unprognostic (1.42e-2)" "potential prognostic favorable (6.80e-5)" "unprognostic (4.55e-2)" "unprognostic (7.29e-2)" "unprognostic (6.42e-2)" "unprognostic (3.43e-2)" "unprognostic (3.40e-3)" "potential prognostic unfavorable (9.49e-6)" "unprognostic (5.87e-2)" "unprognostic (7.47e-2)" "unprognostic (1.79e-1)" "unprognostic (1.88e-2)" "unprognostic (1.05e-3)" "unprognostic (1.79e-1)" "unprognostic (8.39e-2)" "unprognostic (1.70e-2)" "unprognostic (1.99e-2)" "unprognostic (9.00e-2)" "unprognostic (1.35e-1)" "unprognostic (3.25e-2)" "unprognostic (6.71e-2)" "unprognostic (3.49e-2)" EID1 "C15orf3, CRI1, EID-1" ENSG00000255302 "EP300 interacting inhibitor of differentiation 1" Q9Y6B2 15 48878134-48880173 "Predicted intracellular proteins" "Cell cycle, Differentiation, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Decidual stromal cells: 735.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Fibroblasts, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "HPA051122, HPA051123" Approved Supported Nucleoplasm NA Yes "Cluster 10: Non-specific - Membrane trafficking" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 14: Neurons - Synaptic function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 62: Smooth muscle cells - Muscle contraction" 12 Nucleoplasm "HPA051122: , HPA051123: " "unprognostic (2.05e-2)" "unprognostic (9.22e-2)" "unprognostic (6.14e-2)" "unprognostic (1.71e-2)" "unprognostic (4.55e-2)" "unprognostic (1.68e-1)" "unprognostic (2.68e-1)" "unprognostic (6.77e-2)" "unprognostic (6.48e-3)" "unprognostic (8.49e-3)" "validated prognostic favorable (6.37e-10)" "validated prognostic favorable (4.22e-4)" "unprognostic (1.65e-1)" "unprognostic (2.19e-1)" "unprognostic (2.74e-1)" "unprognostic (1.86e-1)" "unprognostic (3.95e-1)" "unprognostic (1.83e-1)" "unprognostic (1.83e-3)" "unprognostic (1.08e-1)" "unprognostic (2.54e-3)" "unprognostic (5.55e-3)" "unprognostic (1.59e-1)" "unprognostic (4.19e-1)" "unprognostic (8.51e-2)" "unprognostic (3.33e-1)" "unprognostic (4.45e-2)" "unprognostic (1.84e-2)" "unprognostic (2.20e-2)" "unprognostic (3.06e-1)" "potential prognostic favorable (6.25e-4)" EID2 "CRI2, EID-2, MGC20452" ENSG00000176396 "EP300 interacting inhibitor of differentiation 2" Q8N6I1 19 39538707-39540161 "Predicted intracellular proteins" "Differentiation, Myogenesis, Transcription, Transcription regulation" "Developmental protein, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 57.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045477 Uncertain Supported Nucleoplasm,Centrosome NA NA "Cluster 24: Non-specific - Transcription" "Cluster 36: Brain & Liver - Signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 4: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 3 Nucleoplasm Centrosome "HPA045477: " "unprognostic (2.41e-1)" "unprognostic (4.76e-1)" "unprognostic (2.07e-1)" "unprognostic (6.97e-2)" "unprognostic (4.41e-3)" "unprognostic (3.66e-2)" "unprognostic (7.01e-2)" "unprognostic (2.60e-1)" "unprognostic (3.99e-2)" "unprognostic (6.82e-2)" "unprognostic (3.80e-3)" "unprognostic (1.44e-1)" "unprognostic (1.38e-1)" "potential prognostic unfavorable (1.86e-5)" "unprognostic (7.93e-2)" "unprognostic (3.62e-2)" "unprognostic (8.08e-3)" "unprognostic (1.43e-2)" "unprognostic (5.37e-2)" "unprognostic (1.01e-1)" "unprognostic (5.08e-2)" "unprognostic (4.41e-2)" "unprognostic (2.76e-1)" "unprognostic (2.13e-3)" "unprognostic (3.15e-2)" "unprognostic (1.73e-1)" "unprognostic (2.96e-1)" "unprognostic (8.63e-2)" "unprognostic (6.51e-2)" "unprognostic (1.85e-1)" "unprognostic (1.24e-2)" EID2B "EID-3, FLJ38944" ENSG00000176401 "EP300 interacting inhibitor of differentiation 2B" Q96D98 19 39530987-39532852 "Predicted intracellular proteins" "Differentiation, Myogenesis, Transcription, Transcription regulation" "Developmental protein, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 15.5" "Cell type enhanced" "Detected in many" "Other brain neurons: 25.1;Respiratory ciliated cells: 23.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064185 Approved NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 65: Brain - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 4: Non-specific - Transcription" "Cluster 98: Neurons - Neurotransmission & signaling" 6 "HPA064185: " "unprognostic (5.59e-2)" "unprognostic (2.26e-1)" "unprognostic (5.71e-2)" "unprognostic (1.33e-2)" "unprognostic (2.41e-1)" "unprognostic (9.73e-2)" "unprognostic (4.19e-2)" "unprognostic (4.56e-2)" "unprognostic (4.83e-2)" "unprognostic (1.64e-1)" "unprognostic (1.60e-2)" "unprognostic (4.66e-2)" "unprognostic (3.23e-3)" "unprognostic (2.22e-2)" "unprognostic (2.79e-1)" "unprognostic (5.58e-2)" "unprognostic (8.38e-2)" "unprognostic (2.08e-1)" "potential prognostic favorable (4.49e-4)" "unprognostic (6.96e-3)" "unprognostic (7.10e-2)" "unprognostic (1.32e-2)" "unprognostic (2.67e-2)" "unprognostic (3.09e-2)" "unprognostic (4.66e-2)" "unprognostic (6.74e-2)" "unprognostic (1.23e-1)" EID3 "FLJ25832, NSE4B, NSMCE4B" ENSG00000255150 "EP300 interacting inhibitor of differentiation 3" Q8N140 12 104303739-104305205 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "testis: 57.2" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 8.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 11.7" "Prostate - Smooth muscle cells, Stomach - Fibroblasts, Testis - Early spermatids" "Not detected" "Not detected" HPA059367 Uncertain Supported Nucleoplasm,Nucleoli NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 57: Testis - Spermatogenesis" "Cluster 12: Non-specific - Vasculature" "Cluster 7: Liver cancer - Metabolism" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 20 "Nucleoplasm, Nucleoli" "HPA059367: " "unprognostic (5.35e-2)" "unprognostic (1.42e-1)" "unprognostic (1.50e-1)" "unprognostic (1.98e-2)" "unprognostic (2.67e-1)" "potential prognostic unfavorable (1.66e-4)" "unprognostic (6.16e-2)" "unprognostic (1.69e-1)" "unprognostic (4.98e-2)" "unprognostic (2.76e-1)" "unprognostic (8.39e-2)" "unprognostic (1.80e-2)" "unprognostic (9.95e-2)" "unprognostic (4.65e-3)" "unprognostic (5.65e-2)" "unprognostic (1.06e-1)" "unprognostic (3.81e-2)" "unprognostic (2.92e-3)" "unprognostic (2.83e-2)" "unprognostic (5.78e-3)" "unprognostic (1.24e-3)" "unprognostic (2.97e-2)" "potential prognostic favorable (6.05e-4)" "unprognostic (1.71e-1)" "unprognostic (3.68e-1)" "unprognostic (4.41e-2)" "unprognostic (1.09e-2)" EIF1 "A121, EIF-1, EIF1A, ISO1, SUI1" ENSG00000173812 "Eukaryotic translation initiation factor 1" P41567 17 41688885-41692668 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 15381.7;Late spermatids: 10962.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 24: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 15: Non-specific - Protein processing" 12 "unprognostic (1.59e-1)" "unprognostic (2.26e-2)" "unprognostic (2.38e-3)" "unprognostic (2.03e-3)" "unprognostic (7.70e-2)" "unprognostic (8.07e-3)" "unprognostic (2.26e-2)" "unprognostic (6.53e-3)" "unprognostic (8.17e-3)" "unprognostic (4.49e-2)" "potential prognostic favorable (4.27e-7)" "unprognostic (1.18e-2)" "unprognostic (5.04e-2)" "unprognostic (2.14e-1)" "unprognostic (2.73e-3)" "unprognostic (6.75e-2)" "unprognostic (3.94e-1)" "unprognostic (6.68e-2)" "unprognostic (6.57e-2)" "unprognostic (1.52e-2)" "unprognostic (3.90e-2)" "potential prognostic favorable (2.99e-4)" "unprognostic (5.05e-3)" "unprognostic (5.35e-2)" "unprognostic (4.97e-2)" "unprognostic (3.02e-2)" "unprognostic (1.67e-2)" "unprognostic (2.82e-1)" "unprognostic (3.09e-1)" "unprognostic (2.19e-2)" "unprognostic (2.04e-1)" EIF1AD "haponin, MGC11102" ENSG00000175376 "Eukaryotic translation initiation factor 1A domain containing" Q8N9N8 11 65996545-66002176 "Essential proteins, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 51.0;Megakaryocytes: 49.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054991, HPA058735" Uncertain Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 24: Non-specific - Unknown function" "Cluster 75: Non-specific - Chaperones and protein folding" 41 "Nucleoplasm, Vesicles" Cytosol "HPA054991: , HPA058735: " "unprognostic (7.70e-2)" "unprognostic (3.55e-2)" "unprognostic (1.04e-1)" "unprognostic (3.46e-2)" "unprognostic (6.81e-2)" "unprognostic (4.46e-2)" "unprognostic (4.46e-2)" "unprognostic (1.47e-1)" "unprognostic (1.60e-2)" "unprognostic (8.58e-3)" "unprognostic (4.52e-3)" "unprognostic (1.59e-2)" "unprognostic (1.09e-1)" "potential prognostic unfavorable (5.13e-4)" "unprognostic (9.14e-2)" "unprognostic (1.02e-3)" "potential prognostic unfavorable (1.61e-4)" "unprognostic (2.85e-1)" "unprognostic (3.14e-1)" "unprognostic (1.12e-1)" "unprognostic (1.01e-1)" "unprognostic (3.04e-3)" "potential prognostic unfavorable (2.75e-4)" "unprognostic (3.52e-3)" "unprognostic (2.89e-2)" "unprognostic (1.02e-1)" "unprognostic (2.07e-1)" "unprognostic (6.80e-2)" "unprognostic (1.62e-1)" "unprognostic (3.56e-1)" "unprognostic (1.95e-2)" EIF1AX "eIF-1A, eIF-4C, EIF1A, EIF4C" ENSG00000173674 "Eukaryotic translation initiation factor 1A X-linked" P47813 X 20124525-20141838 "Essential proteins, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Initiation factor, RNA-binding, tRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 475.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002561 Uncertain Supported Approved Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 26: Keratinocytes - Keratinization" 25 Cytosol "HPA002561: " "unprognostic (1.01e-1)" "unprognostic (1.02e-1)" "unprognostic (1.24e-1)" "unprognostic (4.07e-2)" "unprognostic (8.71e-3)" "unprognostic (5.50e-2)" "unprognostic (1.18e-1)" "unprognostic (1.83e-1)" "unprognostic (1.56e-3)" "unprognostic (2.14e-2)" "potential prognostic favorable (3.80e-6)" "unprognostic (3.79e-2)" "unprognostic (1.36e-2)" "unprognostic (5.04e-3)" "potential prognostic unfavorable (5.64e-4)" "unprognostic (2.62e-3)" "unprognostic (7.22e-3)" "potential prognostic favorable (5.95e-4)" "unprognostic (1.76e-1)" "unprognostic (3.15e-2)" "unprognostic (3.35e-3)" "unprognostic (6.65e-3)" "unprognostic (2.29e-1)" "unprognostic (2.77e-2)" "unprognostic (5.80e-3)" "unprognostic (2.10e-1)" "unprognostic (1.99e-1)" "unprognostic (1.74e-2)" "unprognostic (1.93e-1)" "unprognostic (1.39e-1)" "unprognostic (8.20e-3)" EIF1AY ENSG00000198692 "Eukaryotic translation initiation factor 1A Y-linked" O14602 Y 20575776-20593154 "Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor, RNA-binding, tRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 113.5;tongue: 122.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 155.4;Erythrocyte progenitors: 131.8;Erythrocytes: 126.5;Migrating cytotrophoblasts: 112.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 169.3" "Low region specificity" "Detected in all" HPA002561 Uncertain Supported Approved Cytosol NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 27: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 3 Cytosol "HPA002561: " "unprognostic (2.95e-1)" "unprognostic (4.88e-2)" "unprognostic (4.47e-2)" "unprognostic (2.95e-1)" "unprognostic (5.31e-2)" "unprognostic (1.15e-3)" "unprognostic (5.18e-2)" "unprognostic (2.99e-2)" "unprognostic (1.71e-1)" "unprognostic (4.19e-2)" "unprognostic (3.49e-2)" "unprognostic (1.01e-2)" "unprognostic (1.36e-1)" "unprognostic (3.89e-1)" "unprognostic (1.57e-1)" "unprognostic (4.07e-1)" "unprognostic (5.51e-2)" "unprognostic (2.99e-2)" "unprognostic (7.03e-2)" "unprognostic (2.54e-2)" "unprognostic (7.08e-3)" "unprognostic (1.23e-1)" "unprognostic (4.74e-3)" "unprognostic (2.75e-1)" "unprognostic (6.16e-2)" EIF1B GC20 ENSG00000114784 "Eukaryotic translation initiation factor 1B" O60739 3 40309707-40312424 "Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early primary spermatocytes: 505.5;Oocytes: 1307.8;Platelets: 625.1;Tuft cells: 576.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 103: Non-specific - Basic cellular processes" 12 "unprognostic (7.35e-2)" "unprognostic (2.85e-1)" "potential prognostic unfavorable (8.64e-4)" "unprognostic (1.19e-1)" "unprognostic (1.55e-1)" "unprognostic (1.03e-2)" "unprognostic (3.03e-1)" "unprognostic (1.08e-1)" "unprognostic (1.32e-1)" "unprognostic (9.47e-3)" "validated prognostic favorable (4.99e-8)" "validated prognostic favorable (2.39e-4)" "unprognostic (3.51e-1)" "validated prognostic unfavorable (5.16e-6)" "validated prognostic unfavorable (1.69e-4)" "unprognostic (1.82e-1)" "unprognostic (2.25e-1)" "unprognostic (1.11e-1)" "unprognostic (1.46e-1)" "unprognostic (3.59e-2)" "unprognostic (1.53e-1)" "unprognostic (9.61e-2)" "unprognostic (1.19e-1)" "unprognostic (1.71e-1)" "unprognostic (3.35e-1)" "unprognostic (2.46e-1)" "unprognostic (1.55e-1)" "unprognostic (3.02e-3)" "unprognostic (7.92e-2)" "unprognostic (3.15e-1)" "unprognostic (9.02e-2)" EIF2A EIF-2A ENSG00000144895 "Eukaryotic translation initiation factor 2A" Q9BY44 3 150546678-150586016 "Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis, Translation regulation" "Initiation factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036256, CAB080320" Approved Approved Cytosol NA No 6400 "Cluster 13: Non-specific - Mitochondria" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 15: Non-specific - Protein processing" 28 Cytosol "CAB080320: , HPA036256: " "unprognostic (1.65e-1)" "unprognostic (2.51e-2)" "unprognostic (2.85e-1)" "unprognostic (6.06e-2)" "unprognostic (1.67e-1)" "unprognostic (1.26e-1)" "unprognostic (6.28e-2)" "unprognostic (1.64e-1)" "unprognostic (1.20e-1)" "unprognostic (2.59e-2)" "potential prognostic favorable (1.52e-8)" "unprognostic (1.11e-2)" "unprognostic (1.61e-2)" "unprognostic (1.06e-2)" "potential prognostic unfavorable (5.82e-4)" "unprognostic (1.27e-1)" "unprognostic (3.44e-3)" "unprognostic (5.91e-3)" "unprognostic (8.05e-2)" "unprognostic (1.13e-1)" "potential prognostic unfavorable (9.62e-4)" "potential prognostic unfavorable (8.26e-5)" "unprognostic (4.93e-3)" "unprognostic (3.52e-2)" "unprognostic (5.44e-2)" "unprognostic (2.35e-1)" "unprognostic (1.75e-1)" "unprognostic (1.14e-1)" "unprognostic (2.99e-1)" "unprognostic (1.19e-1)" "unprognostic (1.49e-1)" EIF2AK1 "HCR, hHRI, HRI, KIAA1369" ENSG00000086232 "Eukaryotic translation initiation factor 2 alpha kinase 1" Q9BQI3 7 6022247-6059175 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Kinase, Protein synthesis inhibitor, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 295.1;Erythrocyte progenitors: 318.5;Platelets: 1348.7;Syncytiotrophoblasts: 521.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016496, CAB022082, HPA061675" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 7 Nucleoplasm Cytosol "CAB022082: , HPA016496: , HPA061675: " "unprognostic (3.29e-1)" "unprognostic (2.80e-3)" "unprognostic (1.74e-2)" "unprognostic (8.08e-3)" "unprognostic (9.89e-2)" "unprognostic (1.53e-1)" "unprognostic (2.46e-2)" "unprognostic (1.80e-3)" "unprognostic (1.70e-2)" "potential prognostic unfavorable (3.47e-6)" "potential prognostic favorable (3.16e-4)" "unprognostic (6.69e-2)" "unprognostic (3.87e-1)" "unprognostic (2.70e-3)" "potential prognostic unfavorable (2.64e-4)" "unprognostic (1.87e-2)" "unprognostic (1.77e-2)" "unprognostic (2.23e-2)" "unprognostic (1.91e-1)" "unprognostic (1.20e-1)" "unprognostic (1.17e-2)" "unprognostic (3.81e-2)" "unprognostic (1.49e-1)" "unprognostic (2.72e-2)" "unprognostic (1.15e-1)" "unprognostic (9.40e-2)" "unprognostic (1.75e-1)" "unprognostic (2.22e-1)" "unprognostic (8.92e-2)" "unprognostic (2.60e-2)" "unprognostic (3.26e-2)" EIF2AK2 "PKR, PPP1R83, PRKR" ENSG00000055332 "Eukaryotic translation initiation factor 2 alpha kinase 2" P19525 2 37099210-37157522 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation" "Kinase, RNA-binding, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Disease variant, Dystonia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003845, HPA019795, HPA063893" Approved Enhanced Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 15: Bone marrow - Innate immune response" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 115 Cytosol "CAB003845: , HPA019795: , HPA063893: " "unprognostic (1.70e-1)" "unprognostic (6.33e-2)" "unprognostic (2.40e-1)" "unprognostic (1.00e-1)" "unprognostic (1.03e-1)" "unprognostic (3.25e-2)" "unprognostic (6.80e-2)" "unprognostic (4.34e-2)" "unprognostic (1.48e-1)" "potential prognostic unfavorable (3.55e-6)" "unprognostic (1.91e-3)" "unprognostic (1.41e-1)" "unprognostic (1.66e-2)" "unprognostic (2.54e-3)" "unprognostic (1.29e-1)" "unprognostic (1.59e-3)" "unprognostic (5.10e-3)" "unprognostic (2.16e-1)" "unprognostic (5.02e-2)" "unprognostic (2.65e-1)" "unprognostic (1.76e-1)" "potential prognostic unfavorable (1.70e-4)" "unprognostic (1.23e-3)" "unprognostic (1.31e-1)" "unprognostic (1.52e-1)" "unprognostic (7.55e-3)" "unprognostic (8.49e-2)" "unprognostic (3.57e-1)" "unprognostic (2.36e-1)" "unprognostic (5.94e-2)" "unprognostic (4.11e-2)" EIF2AK3 "PEK, PERK" ENSG00000172071 "Eukaryotic translation initiation factor 2 alpha kinase 3" Q9NZJ5 2 88556741-88691518 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Stress response, Translation regulation, Unfolded protein response" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 20.1" "Cell type enhanced" "Detected in many" "B-cells: 451.6;Epididymal principal cells: 449.7;monocytes: 407.3;Pancreatic acinar cells: 394.5;Plasma cells: 941.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Myeloma: 30.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009204, HPA015737" Approved Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 60: Stomach - Digestion" "Cluster 55: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 23 "Nucleoplasm, Cytosol" Mitochondria "CAB009204: , HPA015737: " "unprognostic (1.01e-1)" "unprognostic (2.11e-1)" "unprognostic (1.98e-1)" "unprognostic (2.37e-1)" "unprognostic (6.01e-2)" "unprognostic (1.58e-1)" "unprognostic (1.36e-1)" "unprognostic (2.54e-1)" "unprognostic (5.14e-2)" "unprognostic (2.62e-2)" "potential prognostic favorable (5.11e-6)" "unprognostic (2.01e-1)" "unprognostic (1.44e-1)" "unprognostic (8.92e-2)" "unprognostic (3.91e-3)" "unprognostic (2.41e-2)" "unprognostic (1.69e-1)" "unprognostic (4.32e-2)" "unprognostic (1.08e-2)" "unprognostic (8.06e-3)" "unprognostic (2.67e-1)" "unprognostic (9.19e-2)" "unprognostic (1.30e-1)" "unprognostic (6.58e-3)" "unprognostic (3.10e-2)" "unprognostic (3.41e-1)" "unprognostic (1.66e-1)" "unprognostic (5.85e-2)" "unprognostic (3.01e-2)" EIF2AK4 "GCN2, KIAA1338" ENSG00000128829 "Eukaryotic translation initiation factor 2 alpha kinase 4" Q9P2K8 15 39934115-40035591 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Activation of host autophagy by virus, Adaptive immunity, Antiviral defense, Cell cycle, Growth arrest, Host-virus interaction, Immunity, Neurogenesis, Stress response, Translation regulation" "Activator, Kinase, RNA-binding, Serine/threonine-protein kinase, Transferase, tRNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 345.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 66.6" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011811 Approved Approved Cytosol NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 73: Brain - Neuronal signaling" "Cluster 34: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 44: Plasma cells - Antibody production & secretion" 4 Cytosol "HPA011811: " "unprognostic (5.17e-2)" "unprognostic (9.61e-2)" "unprognostic (9.53e-2)" "unprognostic (4.15e-1)" "unprognostic (1.89e-1)" "unprognostic (6.26e-2)" "unprognostic (3.11e-1)" "unprognostic (5.08e-2)" "unprognostic (1.57e-1)" "unprognostic (1.19e-1)" "unprognostic (2.65e-3)" "unprognostic (1.00e-1)" "unprognostic (2.84e-1)" "unprognostic (2.62e-1)" "unprognostic (8.76e-2)" "unprognostic (1.59e-2)" "unprognostic (1.35e-2)" "unprognostic (6.61e-3)" "unprognostic (6.70e-2)" "unprognostic (1.57e-1)" "unprognostic (2.13e-1)" "unprognostic (3.79e-2)" "unprognostic (1.04e-1)" "unprognostic (1.79e-2)" "unprognostic (8.06e-2)" "unprognostic (4.08e-2)" "unprognostic (8.04e-2)" "potential prognostic unfavorable (4.65e-4)" "unprognostic (1.88e-1)" "unprognostic (8.15e-2)" "unprognostic (3.51e-2)" EIF2B1 "EIF-2B, EIF-2Balpha, EIF2B, EIF2BA, EIF2Balpha" ENSG00000111361 "Eukaryotic translation initiation factor 2B subunit alpha" Q14232 12 123620406-123633766 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 138.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034258, HPA049509" Approved Approved Cytosol NA NA 9600 "Cluster 25: Non-specific - Unknown function" "Cluster 49: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 46 Cytosol "CAB034258: , HPA049509: " "unprognostic (2.91e-1)" "unprognostic (5.10e-2)" "unprognostic (5.84e-2)" "unprognostic (6.77e-2)" "unprognostic (8.00e-3)" "unprognostic (1.86e-1)" "unprognostic (1.44e-1)" "unprognostic (6.50e-2)" "unprognostic (1.95e-1)" "potential prognostic unfavorable (1.02e-5)" "unprognostic (2.58e-1)" "unprognostic (2.63e-1)" "unprognostic (2.50e-1)" "validated prognostic unfavorable (6.22e-9)" "validated prognostic unfavorable (4.54e-4)" "unprognostic (1.77e-2)" "potential prognostic unfavorable (1.31e-4)" "unprognostic (4.34e-2)" "unprognostic (1.79e-1)" "unprognostic (4.62e-1)" "unprognostic (8.54e-3)" "unprognostic (3.81e-1)" "unprognostic (1.66e-3)" "unprognostic (1.50e-3)" "unprognostic (9.59e-3)" "unprognostic (4.83e-2)" "unprognostic (1.75e-2)" "unprognostic (1.84e-1)" "unprognostic (2.56e-1)" "unprognostic (1.95e-1)" "unprognostic (1.14e-1)" EIF2B2 "EIF-2Bbeta, EIF2B, EIF2Bbeta" ENSG00000119718 "Eukaryotic translation initiation factor 2B subunit beta" P49770 14 75002921-75012366 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 111.8;Syncytiotrophoblasts: 245.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Inner root sheath cells, Skin - Outer root sheath cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005841, CAB037105, HPA048028" Enhanced Approved "Nucleoplasm,Plasma membrane,Focal adhesion sites" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 41 "Plasma membrane, Focal adhesion sites" Nucleoplasm "CAB037105: , HPA005841: , HPA048028: " "unprognostic (1.81e-2)" "unprognostic (5.28e-2)" "unprognostic (1.32e-1)" "unprognostic (1.29e-1)" "unprognostic (7.18e-2)" "unprognostic (1.67e-1)" "unprognostic (4.34e-2)" "unprognostic (1.11e-1)" "unprognostic (1.24e-1)" "unprognostic (1.09e-2)" "unprognostic (1.86e-1)" "unprognostic (1.46e-2)" "unprognostic (1.99e-1)" "potential prognostic unfavorable (1.53e-4)" "unprognostic (2.11e-3)" "unprognostic (7.22e-2)" "unprognostic (4.32e-2)" "unprognostic (1.02e-2)" "unprognostic (1.89e-1)" "unprognostic (3.08e-1)" "unprognostic (7.25e-2)" "unprognostic (7.16e-2)" "unprognostic (2.08e-2)" "unprognostic (8.78e-2)" "unprognostic (1.37e-1)" "unprognostic (4.51e-3)" "unprognostic (3.59e-2)" "unprognostic (5.18e-2)" "unprognostic (1.57e-1)" "unprognostic (3.94e-2)" "unprognostic (3.83e-2)" EIF2B3 "EIF-2B, EIF2Bgamma" ENSG00000070785 "Eukaryotic translation initiation factor 2B subunit gamma" Q9NR50 1 44850522-44986722 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Myonuclei: 444.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skin - Outer root sheath cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024213, HPA024218, HPA024219" Supported Supported Vesicles,Cytosol NA NA 5900 "Cluster 13: Non-specific - Mitochondria" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 32 "Vesicles, Cytosol" "HPA024213: , HPA024218: , HPA024219: " "unprognostic (5.64e-2)" "unprognostic (3.04e-3)" "unprognostic (1.04e-3)" "unprognostic (1.51e-1)" "unprognostic (8.41e-3)" "unprognostic (8.74e-3)" "unprognostic (1.60e-1)" "unprognostic (3.91e-2)" "unprognostic (2.81e-3)" "unprognostic (1.44e-2)" "potential prognostic favorable (1.84e-7)" "unprognostic (1.18e-1)" "unprognostic (4.62e-3)" "potential prognostic unfavorable (2.16e-5)" "unprognostic (4.68e-3)" "unprognostic (1.80e-1)" "unprognostic (1.03e-2)" "unprognostic (4.42e-2)" "unprognostic (7.46e-2)" "unprognostic (2.20e-1)" "unprognostic (2.95e-1)" "unprognostic (1.56e-1)" "unprognostic (7.20e-2)" "unprognostic (2.14e-1)" "unprognostic (5.56e-2)" "potential prognostic favorable (6.74e-4)" "unprognostic (1.23e-2)" "unprognostic (4.56e-2)" "unprognostic (4.97e-2)" "unprognostic (3.13e-1)" "unprognostic (1.81e-1)" EIF2B4 "DKFZP586J0119, EIF-2B, EIF2B, EIF2Bdelta" ENSG00000115211 "Eukaryotic translation initiation factor 2B subunit delta" Q9UI10 2 27364352-27370338 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 223.8;Esophageal apical cells: 110.9;Late primary spermatocytes: 126.2;Late spermatids: 419.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Skin - Hair cortex cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032234, HPA068855" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 24: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 22 "Endoplasmic reticulum" "CAB032234: , HPA068855: " "unprognostic (1.78e-2)" "unprognostic (2.28e-1)" "unprognostic (3.52e-2)" "unprognostic (1.48e-2)" "unprognostic (3.47e-2)" "unprognostic (2.20e-1)" "unprognostic (1.57e-1)" "unprognostic (3.53e-3)" "unprognostic (4.28e-2)" "unprognostic (2.00e-1)" "unprognostic (4.29e-3)" "unprognostic (4.45e-2)" "unprognostic (4.58e-3)" "validated prognostic unfavorable (1.61e-5)" "validated prognostic unfavorable (1.99e-4)" "unprognostic (1.71e-2)" "potential prognostic unfavorable (3.62e-4)" "unprognostic (3.27e-2)" "unprognostic (2.25e-2)" "unprognostic (6.96e-2)" "unprognostic (2.51e-2)" "unprognostic (7.86e-2)" "unprognostic (3.76e-2)" "unprognostic (1.39e-1)" "unprognostic (1.04e-1)" "unprognostic (2.11e-1)" "unprognostic (6.74e-2)" "unprognostic (4.34e-2)" "unprognostic (2.59e-1)" "unprognostic (2.80e-1)" "unprognostic (4.28e-2)" EIF2B5 "EIF-2B, EIF2Bepsilon" ENSG00000145191 "Eukaryotic translation initiation factor 2B subunit epsilon" Q13144 3 184135038-184146127 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015412, HPA064370, HPA069303" Approved Enhanced Cytosol NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 97: Non-specific - Cellular respiration" 60 Cytosol "CAB015412: , HPA064370: , HPA069303: " "unprognostic (6.83e-2)" "unprognostic (1.10e-2)" "unprognostic (3.07e-1)" "unprognostic (1.59e-2)" "unprognostic (1.77e-2)" "unprognostic (3.54e-2)" "unprognostic (5.29e-1)" "potential prognostic favorable (1.94e-4)" "unprognostic (8.19e-2)" "unprognostic (7.09e-2)" "potential prognostic favorable (8.71e-9)" "unprognostic (1.47e-2)" "unprognostic (1.41e-1)" "validated prognostic unfavorable (1.30e-6)" "validated prognostic unfavorable (6.17e-4)" "unprognostic (9.23e-3)" "unprognostic (1.84e-2)" "unprognostic (3.49e-2)" "unprognostic (2.15e-3)" "unprognostic (8.78e-2)" "unprognostic (1.33e-1)" "unprognostic (8.55e-2)" "unprognostic (7.81e-2)" "unprognostic (4.08e-1)" "unprognostic (1.21e-1)" "unprognostic (1.20e-1)" "unprognostic (6.55e-2)" "unprognostic (1.67e-1)" "unprognostic (3.48e-1)" "unprognostic (4.12e-1)" "unprognostic (1.11e-2)" EIF2D LGTN ENSG00000143486 "Eukaryotic translation initiation factor 2D" P41214 1 206571292-206612465 "Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028220 Approved Supported "Nuclear bodies,Cytosol" NA NA "Cluster 18: Non-specific - Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 11: White matter - Signal transduction" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 3 Cytosol "Nuclear bodies" "HPA028220: " "unprognostic (2.49e-1)" "unprognostic (1.98e-1)" "unprognostic (9.02e-2)" "unprognostic (2.03e-1)" "unprognostic (2.50e-1)" "unprognostic (2.55e-1)" "unprognostic (3.11e-1)" "unprognostic (2.60e-1)" "unprognostic (6.72e-3)" "unprognostic (1.04e-3)" "unprognostic (2.49e-1)" "unprognostic (6.41e-3)" "unprognostic (1.01e-2)" "unprognostic (1.60e-2)" "unprognostic (5.48e-2)" "unprognostic (2.12e-1)" "unprognostic (4.88e-2)" "unprognostic (2.68e-1)" "unprognostic (4.05e-1)" "unprognostic (2.88e-2)" "unprognostic (3.80e-1)" "unprognostic (1.50e-1)" "unprognostic (2.33e-1)" "unprognostic (1.98e-1)" "unprognostic (8.33e-2)" "unprognostic (1.29e-1)" "unprognostic (2.38e-1)" "unprognostic (3.11e-1)" "unprognostic (3.23e-2)" "unprognostic (3.75e-3)" EIF2S1 "EIF-2alpha, EIF2, EIF2A" ENSG00000134001 "Eukaryotic translation initiation factor 2 subunit alpha" P05198 14 67360328-67386516 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis, Translation regulation" "Initiation factor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 211.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011663, HPA064885" Supported Enhanced Cytosol NA NA 160000 "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 17: Non-specific - RNA processing" 59 Cytosol "CAB011663: , HPA064885: " "unprognostic (2.57e-2)" "unprognostic (1.14e-2)" "unprognostic (7.40e-2)" "unprognostic (1.20e-1)" "unprognostic (9.85e-2)" "unprognostic (1.52e-1)" "unprognostic (1.11e-1)" "unprognostic (1.74e-1)" "potential prognostic unfavorable (3.90e-4)" "unprognostic (5.02e-2)" "potential prognostic favorable (8.64e-7)" "unprognostic (3.61e-2)" "unprognostic (4.23e-1)" "potential prognostic unfavorable (3.05e-7)" "unprognostic (1.22e-2)" "potential prognostic unfavorable (6.00e-4)" "unprognostic (2.21e-2)" "unprognostic (9.50e-2)" "unprognostic (1.06e-1)" "unprognostic (2.56e-1)" "unprognostic (1.33e-3)" "potential prognostic unfavorable (2.92e-4)" "unprognostic (1.92e-2)" "unprognostic (7.34e-2)" "unprognostic (5.51e-2)" "unprognostic (1.44e-1)" "unprognostic (2.70e-1)" "unprognostic (1.54e-1)" "unprognostic (1.15e-1)" "unprognostic (6.25e-3)" "unprognostic (1.60e-1)" EIF2S2 "EIF2, EIF2beta, PPP1R67" ENSG00000125977 "Eukaryotic translation initiation factor 2 subunit beta" P20042 20 34088309-34112243 "Cancer-related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Initiation factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 682.7;Syncytiotrophoblasts: 691.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034415, HPA041262, HPA041332, HPA065768" Enhanced Approved "Endoplasmic reticulum,Cytosol" NA NA 190000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 71 "Endoplasmic reticulum" Cytosol "CAB034415: , HPA041262: , HPA041332: , HPA065768: " "unprognostic (4.16e-3)" "unprognostic (4.51e-3)" "unprognostic (4.04e-2)" "unprognostic (2.30e-2)" "unprognostic (1.22e-1)" "unprognostic (9.90e-2)" "unprognostic (2.45e-1)" "unprognostic (3.30e-2)" "unprognostic (5.96e-3)" "unprognostic (1.76e-2)" "potential prognostic favorable (3.96e-4)" "unprognostic (1.72e-1)" "unprognostic (1.78e-3)" "validated prognostic unfavorable (2.58e-7)" "validated prognostic unfavorable (8.33e-5)" "unprognostic (1.25e-3)" "unprognostic (1.44e-3)" "unprognostic (9.61e-2)" "unprognostic (4.72e-1)" "unprognostic (6.59e-2)" "unprognostic (1.26e-1)" "unprognostic (1.39e-3)" "unprognostic (1.13e-2)" "potential prognostic unfavorable (8.35e-4)" "unprognostic (4.22e-3)" "unprognostic (3.65e-2)" "unprognostic (4.10e-1)" "unprognostic (7.73e-2)" "unprognostic (1.60e-1)" "unprognostic (2.75e-1)" "unprognostic (4.03e-2)" EIF2S3 "EIF2, EIF2G, EIF2gamma" ENSG00000130741 "Eukaryotic translation initiation factor 2 subunit gamma" P41091 X 24054946-24078810 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Hydrolase, Initiation factor" "Disease variant, Epilepsy, Intellectual disability, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" CAB012471 Approved NA NA 600000 "Cluster 13: Non-specific - Mitochondria" "Cluster 54: Non-specific - Ribosome" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 36: Non-specific - mRNA processing" "Cluster 15: Non-specific - Protein processing" 159 "CAB012471: " "unprognostic (2.71e-1)" "unprognostic (7.97e-2)" "unprognostic (4.88e-3)" "unprognostic (3.50e-1)" "unprognostic (2.32e-1)" "unprognostic (4.26e-2)" "unprognostic (2.83e-1)" "unprognostic (7.61e-2)" "unprognostic (1.37e-3)" "unprognostic (4.04e-3)" "potential prognostic favorable (2.11e-4)" "unprognostic (2.27e-2)" "potential prognostic unfavorable (2.12e-6)" "unprognostic (1.59e-3)" "unprognostic (2.06e-3)" "unprognostic (6.71e-3)" "unprognostic (1.35e-3)" "unprognostic (5.05e-3)" "unprognostic (3.78e-1)" "unprognostic (1.59e-1)" "unprognostic (3.55e-2)" "unprognostic (2.61e-3)" "unprognostic (3.38e-1)" "unprognostic (3.39e-2)" "unprognostic (2.19e-2)" "unprognostic (8.88e-2)" "unprognostic (2.36e-1)" "unprognostic (1.07e-1)" "unprognostic (2.77e-1)" "unprognostic (1.39e-1)" "unprognostic (1.67e-1)" EIF2S3B "eIF-2-gamma2, eIF2gA" ENSG00000180574 "Eukaryotic translation initiation factor 2 subunit gamma B" Q2VIR3 12 10505602-10523135 "Enzymes, Predicted intracellular proteins" "Protein biosynthesis" "Hydrolase, Initiation factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 7.1;Early primary spermatocytes: 13.8;Early spermatids: 8.6;Goblet cells: 12.1;Hepatic stellate cells: 6.5;Late primary spermatocytes: 9.5;Undifferentiated spermatogonia: 8.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 47: Testis - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 70: Intestinal goblet cells - Mucin production" 1 "unprognostic (4.51e-2)" "unprognostic (7.02e-3)" "unprognostic (1.77e-1)" "unprognostic (1.70e-1)" EIF3A "EIF3, eIF3-p170, eIF3-theta, EIF3S10, KIAA0139, TIF32" ENSG00000107581 "Eukaryotic translation initiation factor 3 subunit A" Q14152 10 119033670-119080823 "Essential proteins, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Initiation factor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythrocyte progenitors: 754.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038315, HPA038316" Enhanced Approved Nucleoplasm,Cytosol Yes No 140000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 52: Non-specific - Mitochondria" "Cluster 17: Non-specific - RNA processing" 140 "Nucleoplasm, Cytosol" "HPA038315: , HPA038316: " "unprognostic (2.21e-2)" "unprognostic (1.89e-1)" "unprognostic (3.37e-1)" "potential prognostic unfavorable (1.73e-4)" "unprognostic (1.93e-1)" "unprognostic (7.10e-2)" "unprognostic (1.63e-3)" "unprognostic (1.37e-2)" "unprognostic (4.35e-1)" "unprognostic (5.18e-3)" "potential prognostic favorable (5.51e-7)" "unprognostic (1.08e-2)" "unprognostic (4.31e-2)" "unprognostic (2.93e-2)" "unprognostic (3.33e-2)" "unprognostic (7.84e-2)" "unprognostic (2.42e-3)" "unprognostic (4.09e-2)" "unprognostic (2.99e-1)" "unprognostic (7.64e-2)" "unprognostic (1.20e-3)" "potential prognostic unfavorable (2.03e-4)" "unprognostic (2.86e-2)" "unprognostic (7.53e-2)" "unprognostic (1.57e-1)" "unprognostic (2.42e-1)" "unprognostic (2.62e-1)" "unprognostic (1.74e-1)" "unprognostic (2.33e-1)" "unprognostic (4.23e-2)" "unprognostic (4.79e-2)" EIF3B "EIF3S9, PRT1" ENSG00000106263 "Eukaryotic translation initiation factor 3 subunit B" P55884 7 2354086-2380745 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Breast lactating cells: 241.9;Erythrocyte progenitors: 242.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017562, HPA048983" Approved Supported Nucleoplasm,Cytosol NA NA 230000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 205 Cytosol Nucleoplasm "CAB017562: , HPA048983: " "unprognostic (6.86e-3)" "potential prognostic unfavorable (2.85e-4)" "unprognostic (1.73e-2)" "unprognostic (8.62e-2)" "unprognostic (9.15e-2)" "unprognostic (6.80e-2)" "unprognostic (1.10e-1)" "unprognostic (6.12e-2)" "potential prognostic unfavorable (1.14e-5)" "potential prognostic unfavorable (7.97e-4)" "unprognostic (1.67e-3)" "unprognostic (3.87e-1)" "unprognostic (4.81e-2)" "validated prognostic unfavorable (4.71e-9)" "validated prognostic unfavorable (2.40e-8)" "unprognostic (1.30e-3)" "potential prognostic unfavorable (9.35e-5)" "unprognostic (9.45e-3)" "unprognostic (1.05e-1)" "unprognostic (6.18e-2)" "unprognostic (5.10e-2)" "unprognostic (1.14e-2)" "unprognostic (1.59e-2)" "unprognostic (4.12e-2)" "unprognostic (3.99e-1)" "unprognostic (7.92e-2)" "unprognostic (2.49e-1)" "unprognostic (2.76e-1)" "unprognostic (9.82e-2)" "unprognostic (1.60e-1)" "unprognostic (1.96e-1)" EIF3C "eIF3-p110, EIF3S8" ENSG00000184110 "Eukaryotic translation initiation factor 3 subunit C" Q99613 16 28688558-28735727 "Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bergmann glia: 14.3;Brain excitatory neurons: 30.4;Brain inhibitory neurons: 28.9;Ependymal cells: 24.2;Microglia: 15.8;Oligodendrocyte progenitor cells: 19.7;Oligodendrocytes: 25.4;Other brain neurons: 51.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "CAB034045, HPA047097, HPA049495, HPA050112" Supported Supported Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 54: Non-specific - Transcription" "Cluster 98: Neurons - Neurotransmission & signaling" 69 Cytosol "CAB034045: , HPA047097: , HPA049495: , HPA050112: " "unprognostic (2.94e-3)" "unprognostic (1.44e-1)" "potential prognostic favorable (7.78e-5)" "unprognostic (2.92e-2)" "unprognostic (7.84e-2)" "unprognostic (3.20e-1)" "unprognostic (1.98e-1)" "unprognostic (3.45e-2)" "unprognostic (8.24e-2)" "unprognostic (4.90e-2)" "potential prognostic favorable (3.04e-5)" "unprognostic (3.16e-2)" "unprognostic (1.46e-1)" "unprognostic (7.01e-3)" "unprognostic (1.87e-2)" "unprognostic (2.38e-1)" "potential prognostic unfavorable (6.47e-5)" "unprognostic (2.21e-1)" "unprognostic (9.21e-2)" "unprognostic (6.35e-2)" "unprognostic (1.70e-1)" "unprognostic (7.47e-2)" "unprognostic (1.10e-2)" "unprognostic (1.43e-3)" "unprognostic (4.59e-2)" "unprognostic (5.00e-2)" "unprognostic (9.93e-2)" "unprognostic (2.09e-1)" "unprognostic (2.57e-1)" "unprognostic (9.15e-2)" "unprognostic (1.87e-1)" EIF3CL ENSG00000205609 "Eukaryotic translation initiation factor 3 subunit C like" B5ME19 16 28379579-28403841 "Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 4.1;Hepatic stellate cells: 6.5;Medullary thymic epithelial cells: 7.2;Myonuclei: 4.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "HPA047097, HPA049495, HPA050112" Supported Approved Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 37: Neurons - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 15: Non-specific - Protein processing" 17 Cytosol "HPA047097: , HPA049495: , HPA050112: " "unprognostic (2.78e-2)" "unprognostic (6.49e-2)" "unprognostic (8.36e-3)" "potential prognostic favorable (7.00e-4)" "unprognostic (1.53e-1)" "unprognostic (4.49e-2)" "unprognostic (2.60e-1)" "unprognostic (2.22e-3)" "unprognostic (5.34e-2)" "unprognostic (2.15e-1)" "potential prognostic unfavorable (1.87e-7)" "unprognostic (4.24e-2)" "unprognostic (9.55e-2)" "potential prognostic unfavorable (5.70e-5)" "unprognostic (2.53e-2)" "unprognostic (7.48e-2)" "unprognostic (2.95e-3)" "unprognostic (1.49e-2)" "unprognostic (3.12e-1)" "unprognostic (6.25e-2)" "unprognostic (5.49e-2)" "unprognostic (6.38e-2)" "unprognostic (1.37e-1)" "unprognostic (2.60e-1)" "unprognostic (1.20e-2)" "unprognostic (7.76e-3)" "unprognostic (2.72e-3)" "unprognostic (5.14e-2)" "unprognostic (1.52e-1)" "unprognostic (1.11e-1)" "unprognostic (1.54e-1)" EIF3D "eIF3-p66, eIF3-zeta, EIF3S7" ENSG00000100353 "Eukaryotic translation initiation factor 3 subunit D" O15371 22 36510855-36529184 "Disease related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Initiation factor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 457.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045882, HPA063330, HPA066216" Approved Supported Cytosol NA NA 35000 "Cluster 33: Non-specific - ATP binding" "Cluster 54: Non-specific - Ribosome" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 110 Cytosol "HPA045882: , HPA063330: , HPA066216: " "unprognostic (3.53e-1)" "unprognostic (8.89e-2)" "unprognostic (3.16e-1)" "unprognostic (2.12e-1)" "unprognostic (6.96e-2)" "unprognostic (2.56e-1)" "unprognostic (1.55e-1)" "unprognostic (1.01e-1)" "potential prognostic unfavorable (5.84e-4)" "unprognostic (1.93e-2)" "validated prognostic favorable (3.96e-7)" "validated prognostic favorable (2.33e-4)" "unprognostic (1.97e-1)" "validated prognostic unfavorable (1.43e-4)" "validated prognostic unfavorable (5.02e-4)" "potential prognostic unfavorable (5.59e-5)" "unprognostic (1.96e-3)" "unprognostic (2.98e-2)" "unprognostic (1.79e-1)" "unprognostic (2.52e-2)" "unprognostic (5.61e-2)" "potential prognostic unfavorable (2.64e-4)" "unprognostic (2.10e-1)" "unprognostic (9.80e-2)" "unprognostic (7.48e-3)" "unprognostic (3.99e-2)" "unprognostic (3.57e-1)" "unprognostic (1.12e-1)" "unprognostic (2.70e-1)" "unprognostic (1.51e-1)" "unprognostic (3.18e-2)" EIF3E "eIF3-p48, EIF3S6, INT6" ENSG00000104408 "Eukaryotic translation initiation factor 3 subunit E" P60228 8 108162787-108443496 "Cancer-related genes, Essential proteins, Predicted intracellular proteins, Predicted membrane proteins" "Protein biosynthesis" "Initiation factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Decidual stromal cells: 1314.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023973 Approved Supported Cytosol NA NA 150000 "Cluster 33: Non-specific - ATP binding" "Cluster 54: Non-specific - Ribosome" "Cluster 55: Non-specific - Transcription" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 126 Cytosol "HPA023973: " "unprognostic (8.84e-2)" "unprognostic (2.37e-1)" "unprognostic (2.67e-1)" "unprognostic (1.07e-1)" "unprognostic (5.27e-1)" "unprognostic (1.06e-2)" "unprognostic (3.60e-2)" "unprognostic (5.50e-3)" "unprognostic (1.13e-3)" "unprognostic (7.08e-2)" "potential prognostic unfavorable (1.16e-7)" "unprognostic (5.36e-2)" "unprognostic (7.08e-3)" "potential prognostic unfavorable (2.44e-4)" "unprognostic (1.47e-2)" "unprognostic (1.36e-2)" "unprognostic (1.38e-2)" "unprognostic (1.65e-2)" "unprognostic (2.45e-1)" "unprognostic (1.56e-1)" "unprognostic (4.87e-3)" "unprognostic (4.88e-2)" "potential prognostic unfavorable (3.09e-6)" "unprognostic (1.23e-1)" "unprognostic (2.02e-1)" "unprognostic (1.91e-2)" "unprognostic (3.82e-2)" "unprognostic (2.50e-1)" "unprognostic (5.26e-2)" "unprognostic (1.26e-1)" "unprognostic (3.99e-1)" EIF3F "eIF3-epsilon, eIF3-p47, EIF3S5" ENSG00000175390 "Eukaryotic translation initiation factor 3 subunit F" O00303 11 7970251-8001862 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis, Ubl conjugation pathway" "Hydrolase, Initiation factor, Protease, Thiol protease" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 706.2;Decidual stromal cells: 698.9;Extravillous trophoblasts: 765.8;Late spermatids: 1226.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049250 Approved NA NA 120000 "Cluster 33: Non-specific - ATP binding" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 123 "HPA049250: " "unprognostic (5.98e-2)" "unprognostic (2.34e-1)" "unprognostic (5.74e-3)" "unprognostic (3.12e-2)" "unprognostic (7.16e-2)" "unprognostic (2.42e-2)" "unprognostic (8.66e-2)" "unprognostic (1.97e-1)" "unprognostic (2.82e-1)" "unprognostic (3.39e-1)" "unprognostic (2.46e-2)" "potential prognostic favorable (7.72e-4)" "unprognostic (1.08e-1)" "unprognostic (6.73e-2)" "potential prognostic unfavorable (6.63e-7)" "unprognostic (5.34e-2)" "unprognostic (3.71e-2)" "unprognostic (4.21e-2)" "unprognostic (4.13e-3)" "unprognostic (1.90e-2)" "unprognostic (4.42e-2)" "unprognostic (2.34e-3)" "unprognostic (1.74e-1)" "unprognostic (1.02e-1)" "unprognostic (3.89e-2)" "unprognostic (4.64e-1)" "unprognostic (4.94e-2)" "unprognostic (2.77e-1)" "unprognostic (1.83e-1)" "unprognostic (7.45e-2)" "unprognostic (1.01e-1)" EIF3G "eIF3-delta, eIF3-p44, EIF3S4" ENSG00000130811 "Eukaryotic translation initiation factor 3 subunit G" O75821 19 10115014-10119918 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Late spermatids: 2427.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041997 Approved Enhanced Cytosol NA NA 42000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 24: Non-specific - Transcription" "Cluster 7: Non-specific - Ribosome" "Cluster 23: Non-specific - Transcription" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 139 Cytosol "HPA041997: " "unprognostic (7.09e-3)" "unprognostic (5.38e-2)" "unprognostic (1.11e-2)" "unprognostic (1.26e-1)" "unprognostic (2.89e-1)" "unprognostic (6.13e-2)" "unprognostic (8.71e-2)" "unprognostic (1.32e-1)" "unprognostic (3.13e-2)" "unprognostic (5.11e-2)" "unprognostic (1.12e-3)" "unprognostic (1.42e-1)" "unprognostic (8.16e-2)" "unprognostic (7.08e-3)" "potential prognostic unfavorable (1.04e-4)" "unprognostic (3.52e-2)" "unprognostic (2.25e-2)" "unprognostic (1.70e-1)" "unprognostic (1.12e-2)" "potential prognostic favorable (6.53e-4)" "unprognostic (5.81e-2)" "unprognostic (4.77e-2)" "unprognostic (1.37e-1)" "unprognostic (2.16e-1)" "unprognostic (9.81e-2)" "unprognostic (3.90e-2)" "unprognostic (2.09e-1)" "unprognostic (7.73e-2)" "unprognostic (4.82e-2)" "unprognostic (1.80e-1)" "unprognostic (7.33e-3)" EIF3H "eIF3-gamma, eIF3-p40, EIF3S3" ENSG00000147677 "Eukaryotic translation initiation factor 3 subunit H" O15372 8 116642130-116766925 "Cancer-related genes, Essential proteins, Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1458.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023117, HPA023553" Approved Approved Cytosol NA NA 72000 "Cluster 33: Non-specific - ATP binding" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 40: Non-specific - Unknown function" "Cluster 15: Non-specific - Protein processing" 119 Cytosol "HPA023117: , HPA023553: " "unprognostic (1.57e-1)" "potential prognostic unfavorable (4.29e-4)" "unprognostic (1.53e-1)" "unprognostic (1.36e-2)" "unprognostic (2.05e-1)" "unprognostic (5.12e-3)" "unprognostic (9.25e-2)" "unprognostic (2.97e-2)" "unprognostic (2.80e-3)" "unprognostic (1.67e-3)" "potential prognostic favorable (1.12e-5)" "unprognostic (8.67e-3)" "unprognostic (5.00e-3)" "unprognostic (2.96e-3)" "unprognostic (1.45e-2)" "potential prognostic unfavorable (2.23e-4)" "unprognostic (6.40e-3)" "unprognostic (2.78e-1)" "unprognostic (1.08e-1)" "unprognostic (1.23e-1)" "unprognostic (6.85e-2)" "potential prognostic unfavorable (1.78e-4)" "unprognostic (3.28e-2)" "unprognostic (5.38e-2)" "unprognostic (1.52e-2)" "unprognostic (7.73e-2)" "unprognostic (1.83e-1)" "unprognostic (6.72e-2)" "unprognostic (3.88e-1)" "unprognostic (1.83e-1)" "unprognostic (4.75e-3)" EIF3I "eIF3-beta, eIF3-p36, EIF3S2, TRIP-1" ENSG00000084623 "Eukaryotic translation initiation factor 3 subunit I" Q13347 1 32221077-32245397 "Essential proteins, Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 469.2;Esophageal suprabasal cells: 522.4;Extravillous trophoblasts: 401.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029939, HPA029940" Enhanced Approved Cytosol NA NA 26000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 37: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 101 Cytosol "HPA029939: , HPA029940: " "unprognostic (6.70e-2)" "unprognostic (1.48e-1)" "potential prognostic unfavorable (2.96e-4)" "unprognostic (1.13e-1)" "unprognostic (1.30e-2)" "unprognostic (5.18e-2)" "unprognostic (2.33e-1)" "unprognostic (2.19e-1)" "unprognostic (5.33e-3)" "unprognostic (2.98e-3)" "unprognostic (1.57e-2)" "unprognostic (2.51e-1)" "unprognostic (2.76e-1)" "unprognostic (1.31e-3)" "unprognostic (7.28e-3)" "unprognostic (9.31e-3)" "potential prognostic unfavorable (1.48e-5)" "unprognostic (2.97e-1)" "unprognostic (7.30e-2)" "unprognostic (2.98e-1)" "unprognostic (7.46e-2)" "unprognostic (9.86e-3)" "unprognostic (8.79e-2)" "unprognostic (2.23e-1)" "unprognostic (1.35e-2)" "unprognostic (2.81e-2)" "unprognostic (2.14e-2)" "unprognostic (3.38e-1)" "unprognostic (5.13e-3)" "unprognostic (2.06e-3)" "unprognostic (9.10e-3)" EIF3J "eIF3-alpha, eIF3-p35, EIF3S1" ENSG00000104131 "Eukaryotic translation initiation factor 3 subunit J" O75822 15 44537125-44563029 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 196.4" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050977 Approved Approved Cytosol NA NA 140000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 71 Cytosol "HPA050977: " "unprognostic (4.85e-2)" "unprognostic (7.03e-3)" "unprognostic (3.78e-2)" "unprognostic (1.51e-1)" "unprognostic (9.38e-2)" "unprognostic (3.89e-1)" "unprognostic (1.32e-2)" "unprognostic (5.50e-2)" "unprognostic (1.36e-3)" "unprognostic (1.21e-2)" "potential prognostic favorable (3.92e-5)" "unprognostic (3.86e-2)" "unprognostic (8.17e-2)" "unprognostic (2.80e-3)" "unprognostic (1.35e-3)" "unprognostic (2.42e-3)" "unprognostic (1.14e-2)" "unprognostic (2.90e-1)" "unprognostic (7.40e-2)" "unprognostic (1.13e-1)" "unprognostic (2.77e-1)" "unprognostic (8.64e-3)" "unprognostic (1.68e-3)" "unprognostic (6.08e-3)" "unprognostic (9.68e-2)" "unprognostic (5.38e-2)" "unprognostic (7.19e-2)" "unprognostic (1.14e-1)" "unprognostic (1.59e-1)" "unprognostic (7.53e-2)" "unprognostic (2.97e-1)" EIF3K "ARG134, EIF3S12, HSPC029, M9, PLAC-24, PRO1474, PTD001" ENSG00000178982 "Eukaryotic translation initiation factor 3 subunit K" Q9UBQ5 19 38619082-38636955 "Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 1055.1;Esophageal suprabasal cells: 1086.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045446, HPA054590" Uncertain Supported Cytosol No No 8800 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 4: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 105 Cytosol "HPA045446: , HPA054590: " "unprognostic (2.75e-1)" "unprognostic (3.86e-2)" "unprognostic (1.71e-1)" "potential prognostic favorable (2.46e-5)" "unprognostic (2.32e-1)" "unprognostic (1.75e-1)" "unprognostic (2.50e-1)" "unprognostic (2.05e-3)" "unprognostic (1.57e-1)" "unprognostic (4.74e-1)" "potential prognostic favorable (2.98e-5)" "unprognostic (3.05e-1)" "unprognostic (7.31e-3)" "unprognostic (1.62e-3)" "unprognostic (2.38e-3)" "unprognostic (2.09e-2)" "unprognostic (1.87e-1)" "unprognostic (3.68e-2)" "unprognostic (2.67e-2)" "unprognostic (1.89e-3)" "unprognostic (1.32e-1)" "unprognostic (2.61e-2)" "unprognostic (1.19e-1)" "unprognostic (1.09e-2)" "unprognostic (4.59e-2)" "unprognostic (1.31e-1)" "unprognostic (7.82e-2)" "unprognostic (3.48e-2)" "unprognostic (2.34e-1)" "unprognostic (2.72e-1)" "unprognostic (1.89e-1)" EIF3L "EIF3EIP, EIF3S11, EIF3S6IP, HSPC021, HSPC025" ENSG00000100129 "Eukaryotic translation initiation factor 3 subunit L" Q9Y262 22 37848868-37889407 "Predicted intracellular proteins, Predicted membrane proteins" "Protein biosynthesis" "Initiation factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003028 Approved Approved Nucleoplasm,Nucleoli NA NA 18000 "Cluster 13: Non-specific - Mitochondria" "Cluster 54: Non-specific - Ribosome" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 25: Non-specific - Ribosome" "Cluster 17: Non-specific - RNA processing" 101 Nucleoli Nucleoplasm "HPA003028: " "unprognostic (2.44e-1)" "unprognostic (1.95e-1)" "unprognostic (1.90e-1)" "unprognostic (1.45e-1)" "unprognostic (4.76e-2)" "unprognostic (2.05e-1)" "unprognostic (4.22e-2)" "unprognostic (3.63e-2)" "unprognostic (4.35e-2)" "potential prognostic unfavorable (7.32e-4)" "unprognostic (4.80e-3)" "unprognostic (4.88e-2)" "unprognostic (1.84e-1)" "unprognostic (3.48e-3)" "unprognostic (6.25e-3)" "unprognostic (5.08e-2)" "unprognostic (4.00e-1)" "unprognostic (1.24e-1)" "unprognostic (2.09e-1)" "unprognostic (3.40e-1)" "unprognostic (3.29e-2)" "unprognostic (1.21e-1)" "unprognostic (7.49e-2)" "unprognostic (1.29e-1)" "unprognostic (2.39e-2)" "unprognostic (9.14e-3)" "unprognostic (4.08e-2)" "unprognostic (8.98e-2)" "unprognostic (3.24e-1)" "unprognostic (1.10e-1)" "unprognostic (1.76e-2)" EIF3M "FLJ29030, GA17, hfl-B5, PCID1, TANGO7" ENSG00000149100 "Eukaryotic translation initiation factor 3 subunit M" Q7L2H7 11 32583798-32606264 "Essential proteins, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Initiation factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Decidual stromal cells: 520.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031063 Approved Approved Cytosol NA NA 210000 "Cluster 13: Non-specific - Mitochondria" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 15: Non-specific - Protein processing" 104 Cytosol "HPA031063: " "potential prognostic unfavorable (2.19e-4)" "unprognostic (3.74e-2)" "unprognostic (2.41e-2)" "unprognostic (2.52e-1)" "unprognostic (2.16e-1)" "unprognostic (5.06e-2)" "unprognostic (1.86e-2)" "unprognostic (1.85e-1)" "unprognostic (2.48e-3)" "potential prognostic unfavorable (3.57e-4)" "potential prognostic favorable (9.59e-6)" "unprognostic (3.19e-1)" "unprognostic (7.77e-3)" "validated prognostic unfavorable (7.29e-8)" "validated prognostic unfavorable (3.76e-4)" "validated prognostic unfavorable (1.04e-7)" "validated prognostic unfavorable (7.94e-5)" "unprognostic (2.32e-2)" "unprognostic (1.32e-1)" "unprognostic (4.35e-2)" "unprognostic (3.38e-3)" "potential prognostic unfavorable (3.13e-5)" "unprognostic (3.15e-2)" "unprognostic (8.62e-2)" "unprognostic (1.41e-2)" "unprognostic (7.31e-2)" "unprognostic (9.52e-3)" "unprognostic (5.13e-2)" "unprognostic (1.91e-1)" "unprognostic (3.82e-2)" "unprognostic (2.57e-2)" EIF4A1 "DDX2A, EIF-4A, EIF4A" ENSG00000161960 "Eukaryotic translation initiation factor 4A1" P60842 17 7572824-7579006 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Helicase, Hydrolase, Initiation factor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 51.5;Bergmann glia: 50.2;Brain excitatory neurons: 37.8;Brain inhibitory neurons: 42.9;Choroid plexus epithelial cells: 25.6;Ependymal cells: 36.9;Microglia: 81.7;Oligodendrocyte progenitor cells: 47.5;Oligodendrocytes: 54.1;Other brain neurons: 53.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Colon - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011689, HPA068286" Uncertain Approved Cytosol NA NA 6500000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 21: Non-specific - Metabolism" "Cluster 42: Non-specific - Unknown function" "Cluster 22: Non-specific - Basic cellular functions" 105 Cytosol "CAB011689: , HPA068286: " "potential prognostic unfavorable (1.47e-4)" "unprognostic (7.00e-3)" "unprognostic (9.82e-2)" "unprognostic (1.32e-1)" "unprognostic (6.66e-2)" "unprognostic (2.92e-2)" "unprognostic (2.87e-1)" "unprognostic (1.39e-1)" "potential prognostic unfavorable (1.72e-4)" "unprognostic (1.02e-2)" "unprognostic (1.89e-3)" "unprognostic (6.83e-2)" "unprognostic (7.62e-2)" "potential prognostic unfavorable (2.75e-4)" "unprognostic (8.82e-3)" "potential prognostic unfavorable (2.42e-5)" "unprognostic (1.73e-2)" "unprognostic (2.80e-1)" "unprognostic (3.41e-2)" "unprognostic (3.55e-1)" "unprognostic (1.96e-1)" "unprognostic (8.35e-3)" "unprognostic (3.35e-1)" "unprognostic (2.01e-1)" "unprognostic (2.25e-2)" "unprognostic (2.53e-1)" "unprognostic (1.21e-1)" "unprognostic (1.42e-1)" "unprognostic (5.44e-2)" "unprognostic (3.21e-1)" "unprognostic (8.52e-2)" EIF4A2 "BM-010, DDX2B, EIF4A, EIF4F" ENSG00000156976 "Eukaryotic translation initiation factor 4A2" Q14240 3 186783205-186789897 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Helicase, Hydrolase, Initiation factor, RNA-binding" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1755.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011690, HPA068286" Uncertain Approved Cytosol NA NA 3800000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 84: Apical squamous epithelium - Cornification" 59 Cytosol "CAB011690: , HPA068286: " "unprognostic (1.35e-1)" "unprognostic (1.17e-1)" "unprognostic (4.74e-1)" "unprognostic (2.66e-1)" "unprognostic (4.91e-3)" "unprognostic (6.04e-3)" "unprognostic (3.53e-2)" "unprognostic (2.09e-2)" "unprognostic (2.34e-3)" "unprognostic (3.93e-1)" "potential prognostic favorable (1.82e-4)" "unprognostic (1.64e-3)" "unprognostic (7.88e-2)" "unprognostic (1.59e-1)" "unprognostic (7.03e-3)" "unprognostic (1.19e-1)" "unprognostic (6.27e-2)" "unprognostic (2.51e-2)" "unprognostic (1.55e-2)" "unprognostic (3.71e-1)" "unprognostic (1.16e-1)" "unprognostic (2.31e-1)" "unprognostic (7.22e-3)" "unprognostic (1.65e-1)" "unprognostic (8.52e-2)" "unprognostic (2.19e-1)" "unprognostic (2.36e-1)" "unprognostic (1.10e-1)" "unprognostic (2.35e-1)" "unprognostic (1.19e-1)" "unprognostic (1.84e-2)" EIF4A3 "DDX48, EIF4AIII, Fal1, KIAA0111" ENSG00000141543 "Eukaryotic translation initiation factor 4A3" P38919 17 80134369-80147151 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "mRNA processing, mRNA splicing, mRNA transport, Nonsense-mediated mRNA decay, rRNA processing, Translation regulation, Transport" "Helicase, Hydrolase, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "pDCs: 420.9;Urothelial cells: 406.2" "Cell type enhanced" "Detected in all" "vascular associated smooth muscle cell: 91.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021878 Supported Supported Nucleoplasm,Vesicles,Cytosol NA NA 400000 "Cluster 13: Non-specific - Mitochondria" "Cluster 15: Bone marrow - Innate immune response" "Cluster 55: Non-specific - Transcription" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 103: Non-specific - Basic cellular processes" 159 Nucleoplasm "Vesicles, Cytosol" "HPA021878: " "unprognostic (1.55e-2)" "unprognostic (1.84e-2)" "unprognostic (1.14e-1)" "unprognostic (6.67e-2)" "unprognostic (1.28e-2)" "unprognostic (1.59e-1)" "unprognostic (1.98e-1)" "unprognostic (1.38e-2)" "unprognostic (2.88e-3)" "unprognostic (6.59e-2)" "potential prognostic favorable (3.15e-4)" "unprognostic (1.02e-2)" "unprognostic (5.39e-3)" "validated prognostic unfavorable (2.57e-4)" "validated prognostic unfavorable (3.42e-7)" "unprognostic (3.08e-3)" "potential prognostic unfavorable (1.41e-5)" "unprognostic (1.74e-1)" "unprognostic (3.00e-2)" "unprognostic (4.12e-1)" "unprognostic (3.36e-2)" "unprognostic (4.64e-2)" "unprognostic (1.24e-1)" "unprognostic (1.96e-2)" "unprognostic (6.52e-2)" "unprognostic (2.26e-1)" "unprognostic (2.01e-1)" "unprognostic (2.98e-2)" "unprognostic (3.78e-1)" "unprognostic (3.82e-1)" "unprognostic (3.25e-1)" EIF4B ENSG00000063046 "Eukaryotic translation initiation factor 4B" P23588 12 53006282-53042215 "Essential proteins, Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 907.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039072, HPA046164" Approved Approved "Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA 1200000 "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 73 "Endoplasmic reticulum, Cytosol" "Plasma membrane" "HPA039072: , HPA046164: " "unprognostic (3.45e-2)" "unprognostic (4.41e-2)" "unprognostic (1.70e-1)" "unprognostic (5.04e-3)" "unprognostic (8.93e-2)" "unprognostic (1.27e-1)" "unprognostic (7.60e-2)" "unprognostic (2.44e-2)" "unprognostic (1.37e-2)" "unprognostic (1.08e-2)" "validated prognostic favorable (1.57e-9)" "validated prognostic favorable (2.06e-5)" "unprognostic (1.26e-1)" "unprognostic (1.34e-2)" "potential prognostic unfavorable (2.67e-4)" "unprognostic (1.82e-1)" "unprognostic (2.50e-2)" "unprognostic (1.01e-1)" "unprognostic (8.74e-2)" "unprognostic (5.67e-3)" "unprognostic (1.60e-2)" "unprognostic (2.28e-1)" "unprognostic (3.29e-2)" "unprognostic (8.28e-2)" "potential prognostic favorable (4.37e-4)" "unprognostic (2.91e-1)" "unprognostic (5.84e-2)" "unprognostic (2.69e-1)" "unprognostic (1.12e-1)" "unprognostic (1.39e-1)" "unprognostic (2.90e-2)" EIF4E "EIF4E1, EIF4EL1, EIF4F" ENSG00000151247 "Eukaryotic translation initiation factor 4E" P06730 4 98879276-98929133 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, mRNA transport, Protein biosynthesis, Translation regulation, Transport" "Initiation factor, RNA-binding" "Autism, Autism spectrum disorder, Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 320.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004077, CAB016316, HPA068358" Supported Supported "Nucleoplasm,Cytosol,Cytoplasmic bodies" NA NA 160000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 39: Testis - Nuclear processes" "Cluster 21: Non-specific - Metabolism" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 102 "Cytosol, Cytoplasmic bodies" Nucleoplasm "CAB004077: , CAB016316: , HPA068358: " "unprognostic (3.04e-3)" "unprognostic (3.64e-3)" "unprognostic (2.80e-3)" "unprognostic (8.73e-2)" "unprognostic (4.69e-3)" "unprognostic (3.65e-2)" "unprognostic (3.37e-2)" "unprognostic (2.46e-2)" "unprognostic (4.86e-2)" "unprognostic (3.44e-2)" "potential prognostic favorable (3.34e-7)" "unprognostic (1.85e-3)" "unprognostic (1.67e-1)" "potential prognostic unfavorable (9.29e-6)" "unprognostic (5.04e-2)" "unprognostic (5.65e-3)" "unprognostic (4.33e-3)" "unprognostic (5.10e-2)" "unprognostic (1.50e-1)" "unprognostic (1.24e-2)" "unprognostic (9.64e-3)" "unprognostic (1.55e-2)" "unprognostic (1.04e-2)" "unprognostic (1.02e-1)" "unprognostic (6.96e-2)" "unprognostic (8.95e-2)" "unprognostic (2.03e-1)" "unprognostic (2.51e-1)" "unprognostic (5.69e-2)" "unprognostic (6.89e-2)" "unprognostic (7.25e-2)" EIF4E1B FLJ36951 ENSG00000175766 "Eukaryotic translation initiation factor 4E family member 1B" A6NMX2 5 176630618-176646644 "Predicted intracellular proteins" "Protein biosynthesis, Translation regulation" "Initiation factor, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.4;retina: 2.5" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 47.6;Oocytes: 92.1;Retinal amacrine cells: 24.1;Retinal bipolar cells: 26.4;Retinal ganglion cells: 27.0;Retinal horizontal cells: 18.0;Rod photoreceptor cells: 39.6;Somatotrophs: 10.7" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Beta cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA045045 Approved NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 37: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 5 "HPA045045: " "unprognostic (2.41e-2)" EIF4E2 "4EHP, EIF4EL3, IF4e" ENSG00000135930 "Eukaryotic translation initiation factor 4E family member 2" O60573 2 232550659-232583644 "Predicted intracellular proteins" "Protein biosynthesis, RNA-mediated gene silencing, Translation regulation" "Initiation factor, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 277.5;Late spermatids: 489.4;Myonuclei: 253.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019253, HPA077074" Approved Mitochondria,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 73 Mitochondria Cytosol "HPA019253: , HPA077074: " "unprognostic (1.08e-1)" "unprognostic (1.65e-1)" "unprognostic (4.28e-1)" "unprognostic (9.46e-2)" "unprognostic (1.86e-1)" "unprognostic (8.02e-2)" "unprognostic (1.37e-1)" "unprognostic (1.46e-1)" "unprognostic (5.57e-2)" "unprognostic (4.44e-3)" "unprognostic (4.34e-2)" "unprognostic (1.26e-2)" "unprognostic (3.95e-2)" "validated prognostic unfavorable (2.59e-5)" "validated prognostic unfavorable (5.07e-4)" "unprognostic (6.25e-3)" "unprognostic (7.27e-3)" "unprognostic (3.14e-1)" "unprognostic (6.09e-2)" "unprognostic (1.02e-1)" "unprognostic (2.01e-1)" "unprognostic (5.86e-3)" "unprognostic (1.48e-3)" "unprognostic (6.37e-2)" "unprognostic (1.51e-2)" "unprognostic (2.23e-1)" "unprognostic (1.40e-2)" "unprognostic (1.43e-1)" "unprognostic (8.95e-3)" "unprognostic (3.32e-2)" "unprognostic (1.60e-1)" EIF4E3 MGC39820 ENSG00000163412 "Eukaryotic translation initiation factor 4E family member 3" Q8N5X7 3 71675414-71754773 "Predicted intracellular proteins" "Protein biosynthesis, Translation regulation" "Initiation factor, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 15.2;Brain inhibitory neurons: 15.1;Distal convoluted tubule cells: 30.4;Loop of henle epithelial cells: 26.4;Neutrophils: 13.2;Other brain neurons: 12.0;Papillary tip epithelial cells: 19.3;Podocytes: 36.4;Proximal tubule cells: 19.3;Renal collecting duct intercalated cells: 16.2;Renal collecting duct principal cells: 18.8;Renal connecting tubule cells: 29.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 14.7" "Group enriched" "Detected in many" 7 "granulocytes: 14.7;monocytes: 4.2;T-cells: 5.7" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058649, HPA076465" Approved Approved "Nucleoli fibrillar center" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 51: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 105: Non-specific - Mixed function" 2 "Nucleoli fibrillar center" "HPA058649: , HPA076465: " "unprognostic (3.52e-2)" "unprognostic (2.83e-2)" "unprognostic (3.11e-2)" "unprognostic (5.15e-2)" "unprognostic (9.61e-3)" "unprognostic (2.35e-2)" "unprognostic (1.57e-1)" "unprognostic (1.50e-1)" "unprognostic (2.17e-1)" "unprognostic (5.30e-2)" "potential prognostic favorable (1.31e-8)" "unprognostic (3.48e-3)" "unprognostic (7.35e-2)" "unprognostic (2.02e-2)" "unprognostic (1.91e-3)" "unprognostic (1.58e-2)" "unprognostic (1.17e-2)" "unprognostic (2.72e-2)" "unprognostic (4.55e-2)" "potential prognostic favorable (3.83e-5)" "unprognostic (1.22e-1)" "unprognostic (3.81e-1)" "unprognostic (3.77e-1)" "unprognostic (3.09e-1)" "unprognostic (6.87e-2)" "unprognostic (5.15e-3)" "unprognostic (1.52e-1)" "unprognostic (2.49e-1)" "unprognostic (9.97e-2)" "unprognostic (1.77e-1)" "unprognostic (1.12e-1)" EIF4EBP1 "4E-BP1, PHAS-I" ENSG00000187840 "Eukaryotic translation initiation factor 4E binding protein 1" Q13541 8 38030534-38060365 "Cancer-related genes, Predicted intracellular proteins" "Translation regulation" "Protein synthesis inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 309.6" "Cell type enhanced" "Detected in many" "Breast lactating cells: 249.4;Esophageal apical cells: 504.0;Esophageal basal cells: 492.6;Esophageal suprabasal cells: 550.3;Extravillous trophoblasts: 290.7;Gastric progenitor cells: 269.2;Hofbauer cells: 299.0;Pancreatic acinar cells: 435.8;Salivary acinar cells: 282.6" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 16.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB005032, CAB005039, HPA023501" Supported Supported Nucleoplasm,Cytosol NA NA 33000 "Cluster 29: Non-specific - Unknown function" "Cluster 8: Pancreas - Proteolysis" "Cluster 39: Astrocytes - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 85: Squamous epithelial cells - Keratinization" 28 "Nucleoplasm, Cytosol" "CAB005032: , CAB005039: , HPA023501: " "unprognostic (1.07e-1)" "unprognostic (2.00e-3)" "unprognostic (6.45e-3)" "unprognostic (8.02e-3)" "unprognostic (1.67e-1)" "potential prognostic unfavorable (6.26e-5)" "unprognostic (5.01e-2)" "unprognostic (1.51e-1)" "unprognostic (2.88e-1)" "potential prognostic unfavorable (3.09e-5)" "potential prognostic unfavorable (6.97e-8)" "unprognostic (1.23e-3)" "potential prognostic unfavorable (3.28e-8)" "potential prognostic unfavorable (9.01e-4)" "unprognostic (2.92e-2)" "unprognostic (4.68e-3)" "unprognostic (2.29e-3)" "unprognostic (1.98e-2)" "unprognostic (4.17e-1)" "unprognostic (2.69e-2)" "unprognostic (2.85e-1)" "unprognostic (1.55e-3)" "unprognostic (2.25e-1)" "unprognostic (3.24e-1)" "unprognostic (3.01e-1)" "unprognostic (4.18e-2)" "unprognostic (2.95e-1)" "unprognostic (1.69e-1)" "unprognostic (2.38e-1)" "unprognostic (1.57e-2)" "unprognostic (9.31e-3)" EIF4EBP2 ENSG00000148730 "Eukaryotic translation initiation factor 4E binding protein 2" Q13542 10 70404145-70428618 "Predicted intracellular proteins" "Translation regulation" "Protein synthesis inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 422.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019415, HPA037410, HPA061665" Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 84: Apical squamous epithelium - Cornification" 6 "Nucleoplasm, Mitochondria" "CAB019415: , HPA037410: , HPA061665: " "potential prognostic favorable (1.31e-4)" "unprognostic (3.76e-2)" "unprognostic (6.14e-2)" "unprognostic (7.20e-2)" "unprognostic (1.19e-1)" "unprognostic (1.14e-2)" "unprognostic (1.35e-1)" "unprognostic (1.02e-3)" "unprognostic (1.88e-1)" "unprognostic (2.30e-1)" "validated prognostic favorable (6.62e-11)" "validated prognostic favorable (3.76e-8)" "unprognostic (3.01e-3)" "unprognostic (2.21e-1)" "unprognostic (1.22e-2)" "unprognostic (1.65e-1)" "unprognostic (1.66e-2)" "unprognostic (8.11e-2)" "unprognostic (1.45e-2)" "unprognostic (4.42e-2)" "unprognostic (3.55e-3)" "unprognostic (6.49e-2)" "unprognostic (3.60e-2)" "unprognostic (1.29e-1)" "unprognostic (3.86e-1)" "unprognostic (6.51e-2)" "unprognostic (8.56e-2)" "unprognostic (3.75e-1)" "unprognostic (2.56e-1)" "unprognostic (6.77e-2)" "unprognostic (3.28e-1)" EIF4EBP3 4E-BP3 ENSG00000243056 "Eukaryotic translation initiation factor 4E binding protein 3" O60516 5 140547662-140549576 "Metabolic proteins, Predicted intracellular proteins" "Translation regulation" "Protein synthesis inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 17.0;Enteric stem cells: 23.6;Enteric transient amplifying cells: 15.8;Enterocytes: 34.0;Epididymal clear cells: 36.7;Epididymal efferent duct absorptive cells: 36.1;Epididymal efferent duct ciliated cells: 21.0;Fallopian tube ciliated cells: 14.9;Foveolar cells: 14.3;Gastric chief cells: 29.5;Mucous neck cells: 15.6;Paneth cells: 19.3;Parietal cells: 38.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "prostate cancer: 38.6" "Breast - Breast glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA045537 Uncertain NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 35: RS4;11 - Unknown function" "Cluster 15: Non-specific - Protein processing" 7 "HPA045537: " "unprognostic (2.40e-1)" "unprognostic (1.33e-1)" "unprognostic (1.44e-1)" "unprognostic (2.69e-3)" "unprognostic (1.11e-2)" "unprognostic (3.66e-2)" "unprognostic (6.69e-3)" "unprognostic (5.78e-3)" "unprognostic (1.34e-3)" "unprognostic (2.00e-1)" "potential prognostic favorable (3.73e-5)" "unprognostic (9.83e-2)" "unprognostic (1.84e-2)" "unprognostic (6.41e-2)" "unprognostic (3.59e-1)" "unprognostic (1.17e-1)" "unprognostic (8.05e-2)" "unprognostic (3.52e-1)" "unprognostic (1.51e-2)" "unprognostic (3.34e-2)" "unprognostic (9.53e-2)" "unprognostic (3.35e-3)" "unprognostic (2.13e-2)" "unprognostic (6.26e-2)" "unprognostic (1.25e-3)" "unprognostic (1.33e-1)" "unprognostic (1.09e-1)" "unprognostic (9.08e-2)" "unprognostic (9.73e-2)" "unprognostic (1.23e-1)" "unprognostic (1.48e-1)" EIF4ENIF1 "2610509L04Rik, 4E-T, Clast4, FLJ21601" ENSG00000184708 "Eukaryotic translation initiation factor 4E nuclear import factor 1" Q9NRA8 22 31436977-31496108 "Plasma proteins, Predicted intracellular proteins" "Protein transport, RNA-mediated gene silencing, Translation regulation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 156.1;Oocytes: 128.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001619, HPA002078" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 67: Testis - Mixed function" "Cluster 16: Non-specific - Transcription" "Cluster 66: Non-specific - Mitochondria" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 46 Vesicles Cytosol "HPA001619: , HPA002078: " "unprognostic (3.31e-2)" "unprognostic (9.01e-2)" "unprognostic (4.83e-1)" "unprognostic (2.96e-2)" "unprognostic (7.53e-2)" "unprognostic (3.08e-1)" "unprognostic (8.07e-2)" "unprognostic (1.68e-1)" "unprognostic (3.15e-1)" "unprognostic (1.30e-1)" "validated prognostic favorable (1.63e-4)" "validated prognostic favorable (1.45e-4)" "potential prognostic favorable (1.36e-4)" "potential prognostic unfavorable (1.61e-4)" "unprognostic (4.48e-2)" "unprognostic (1.82e-1)" "unprognostic (8.13e-2)" "unprognostic (1.93e-1)" "potential prognostic favorable (4.36e-4)" "unprognostic (3.31e-1)" "unprognostic (7.06e-2)" "unprognostic (5.42e-2)" "unprognostic (1.12e-1)" "unprognostic (2.30e-1)" "unprognostic (4.84e-3)" "unprognostic (1.01e-1)" "unprognostic (1.35e-2)" "unprognostic (5.69e-2)" "unprognostic (3.22e-1)" "unprognostic (5.01e-2)" "unprognostic (1.14e-1)" EIF4G1 "EIF4F, EIF4G, p220, PARK18" ENSG00000114867 "Eukaryotic translation initiation factor 4 gamma 1" Q04637 3 184314495-184335358 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis, Translation regulation" "Initiation factor, RNA-binding, Translational shunt" "Cancer-related genes, Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 321.6;Late spermatids: 314.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB014774, HPA028487, HPA043866" Approved Supported Cytosol NA NA 480000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 17: Non-specific - RNA processing" 108 Cytosol "CAB014774: , HPA028487: , HPA043866: " "unprognostic (3.33e-1)" "unprognostic (5.45e-3)" "unprognostic (9.40e-2)" "unprognostic (3.47e-3)" "unprognostic (1.03e-1)" "unprognostic (2.96e-1)" "unprognostic (2.12e-1)" "unprognostic (6.01e-2)" "unprognostic (1.35e-1)" "unprognostic (3.49e-2)" "potential prognostic favorable (6.40e-5)" "unprognostic (2.24e-1)" "unprognostic (2.19e-1)" "unprognostic (1.06e-1)" "unprognostic (5.48e-2)" "unprognostic (1.04e-3)" "potential prognostic unfavorable (5.59e-6)" "unprognostic (1.03e-1)" "unprognostic (6.43e-3)" "unprognostic (1.57e-1)" "unprognostic (2.30e-2)" "potential prognostic unfavorable (1.92e-4)" "unprognostic (9.73e-2)" "unprognostic (8.72e-2)" "unprognostic (1.47e-1)" "unprognostic (5.37e-2)" "unprognostic (1.89e-1)" "unprognostic (4.08e-1)" "unprognostic (5.39e-1)" "unprognostic (1.80e-2)" "unprognostic (2.23e-1)" EIF4G2 "DAP5, NAT1, p97" ENSG00000110321 "Eukaryotic translation initiation factor 4 gamma 2" P78344 11 10797050-10808940 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis, Translation regulation" "Initiation factor, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1473.0;Syncytiotrophoblasts: 1414.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005163, HPA006773, HPA016965" Approved Enhanced Cytosol NA NA 36000 "Cluster 40: Monocytes - Innate immune response" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 27 Cytosol "CAB005163: , HPA006773: , HPA016965: " "unprognostic (1.20e-1)" "unprognostic (4.66e-3)" "unprognostic (2.91e-1)" "unprognostic (3.98e-2)" "unprognostic (1.30e-1)" "unprognostic (8.76e-2)" "unprognostic (3.18e-2)" "unprognostic (1.83e-3)" "unprognostic (1.39e-1)" "unprognostic (4.76e-2)" "potential prognostic favorable (2.90e-6)" "unprognostic (3.18e-3)" "unprognostic (1.29e-1)" "potential prognostic unfavorable (2.40e-4)" "unprognostic (2.34e-2)" "unprognostic (1.29e-1)" "unprognostic (1.42e-3)" "unprognostic (2.05e-3)" "unprognostic (8.97e-2)" "unprognostic (3.00e-1)" "potential prognostic unfavorable (9.51e-4)" "unprognostic (2.40e-2)" "unprognostic (6.01e-2)" "unprognostic (8.82e-2)" "unprognostic (2.17e-2)" "unprognostic (2.00e-1)" "unprognostic (6.96e-2)" "unprognostic (1.26e-2)" "unprognostic (4.73e-1)" "unprognostic (8.98e-2)" "unprognostic (2.24e-1)" EIF4G3 eIF4GII ENSG00000075151 "Eukaryotic translation initiation factor 4 gamma 3" O43432 1 20806292-21177285 "Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis, Translation regulation" "Initiation factor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Choroid plexus epithelial cells: 2146.1;Neutrophil progenitors: 1639.9;Neutrophils: 1801.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025031, HPA025039, HPA025041" Enhanced Approved Cytosol NA NA 60000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 34 Cytosol "HPA025031: , HPA025039: , HPA025041: " "unprognostic (3.50e-2)" "unprognostic (4.77e-2)" "unprognostic (1.61e-1)" "unprognostic (2.02e-2)" "unprognostic (7.85e-3)" "unprognostic (2.24e-2)" "unprognostic (7.16e-2)" "unprognostic (1.30e-1)" "unprognostic (1.45e-1)" "unprognostic (1.39e-3)" "potential prognostic favorable (3.31e-4)" "unprognostic (5.01e-3)" "unprognostic (4.15e-1)" "potential prognostic unfavorable (6.14e-4)" "unprognostic (3.01e-1)" "unprognostic (5.19e-2)" "unprognostic (1.63e-1)" "unprognostic (8.50e-2)" "unprognostic (9.32e-2)" "unprognostic (3.05e-3)" "unprognostic (5.95e-2)" "unprognostic (5.91e-2)" "unprognostic (2.65e-1)" "unprognostic (9.01e-2)" "unprognostic (2.43e-1)" "unprognostic (1.85e-2)" "unprognostic (7.81e-2)" "unprognostic (2.54e-1)" "unprognostic (1.75e-1)" "unprognostic (4.07e-2)" "unprognostic (1.32e-1)" EIF4H "KIAA0038, WBSCR1, WSCR1" ENSG00000106682 "Eukaryotic translation initiation factor 4H" Q15056 7 74174231-74197122 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Initiation factor, RNA-binding" "Cancer-related genes, Williams-Beuren syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 7 "Early spermatids: 1195.3;Late spermatids: 4262.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030542 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 640000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 24: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 13 Cytosol "Nucleoplasm, Nuclear bodies" "HPA030542: " "unprognostic (4.19e-3)" "unprognostic (2.40e-1)" "unprognostic (1.42e-1)" "unprognostic (9.09e-2)" "unprognostic (6.59e-2)" "unprognostic (1.99e-2)" "unprognostic (1.76e-2)" "unprognostic (7.25e-3)" "unprognostic (7.30e-3)" "unprognostic (5.70e-2)" "potential prognostic favorable (1.31e-7)" "unprognostic (1.64e-2)" "unprognostic (1.64e-1)" "unprognostic (5.47e-3)" "potential prognostic unfavorable (1.80e-5)" "validated prognostic unfavorable (8.46e-6)" "validated prognostic unfavorable (5.26e-4)" "unprognostic (4.35e-2)" "unprognostic (1.14e-1)" "unprognostic (4.82e-2)" "unprognostic (2.69e-1)" "unprognostic (1.99e-2)" "unprognostic (6.90e-2)" "unprognostic (1.02e-1)" "unprognostic (6.81e-2)" "unprognostic (3.44e-2)" "unprognostic (3.09e-1)" "unprognostic (3.49e-2)" "unprognostic (1.70e-1)" "unprognostic (1.89e-1)" "unprognostic (7.05e-2)" EIF5 ENSG00000100664 "Eukaryotic translation initiation factor 5" P55010 14 103333544-103345025 "Essential proteins, Predicted intracellular proteins" "Protein biosynthesis" "GTPase activation, Initiation factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 1162.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000867, CAB004226" Supported Approved "Plasma membrane,Primary cilium,Primary cilium tip,Cytosol" NA NA 93000 "Cluster 22: Eosinophils - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 20: Myeloma - Immune response" "Cluster 20: Non-specific - Transcription regulation" 96 Cytosol "Plasma membrane, Primary cilium, Primary cilium tip" "CAB004226: , HPA000867: " "unprognostic (1.37e-1)" "unprognostic (3.59e-2)" "unprognostic (3.96e-2)" "unprognostic (2.70e-2)" "unprognostic (1.22e-1)" "unprognostic (1.72e-1)" "unprognostic (2.06e-1)" "unprognostic (7.30e-2)" "unprognostic (2.80e-1)" "unprognostic (1.11e-2)" "potential prognostic favorable (5.69e-7)" "unprognostic (1.68e-2)" "potential prognostic favorable (6.55e-4)" "unprognostic (3.68e-2)" "unprognostic (8.51e-2)" "unprognostic (1.66e-1)" "unprognostic (3.19e-2)" "unprognostic (1.76e-2)" "unprognostic (1.47e-2)" "unprognostic (2.31e-1)" "unprognostic (4.35e-3)" "unprognostic (2.13e-2)" "unprognostic (8.28e-2)" "unprognostic (2.16e-3)" "unprognostic (3.64e-2)" "unprognostic (1.09e-1)" "unprognostic (6.16e-2)" "unprognostic (1.61e-1)" "unprognostic (1.31e-1)" "unprognostic (1.95e-2)" "unprognostic (2.13e-1)" EIF5A "EIF-5A, EIF5A1, MGC104255, MGC99547" ENSG00000132507 "Eukaryotic translation initiation factor 5A" P63241 17 7306999-7312463 "Cancer-related genes, Disease related genes, Essential proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein biosynthesis" "Elongation factor, RNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 79.7;Megakaryocyte progenitors: 67.3;Megakaryocytes: 61.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Stomach - Mitotic cells (Stomach)" "CAB005042, HPA061298, HPA074052" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 24: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 28 Cytosol "Nucleoplasm, Plasma membrane" "CAB005042: , HPA061298: , HPA074052: " "potential prognostic unfavorable (3.49e-4)" "unprognostic (2.64e-2)" "unprognostic (1.23e-1)" "unprognostic (8.12e-2)" "unprognostic (6.32e-2)" "unprognostic (2.27e-2)" "unprognostic (2.26e-1)" "unprognostic (4.53e-2)" "unprognostic (4.86e-2)" "unprognostic (2.22e-2)" "validated prognostic unfavorable (2.37e-6)" "validated prognostic unfavorable (1.27e-5)" "unprognostic (9.52e-2)" "unprognostic (2.09e-3)" "unprognostic (1.67e-2)" "potential prognostic unfavorable (5.28e-9)" "unprognostic (6.91e-3)" "unprognostic (1.17e-1)" "unprognostic (2.28e-1)" "unprognostic (6.83e-2)" "unprognostic (3.49e-2)" "unprognostic (2.57e-2)" "unprognostic (2.61e-1)" "unprognostic (9.24e-2)" "unprognostic (1.45e-1)" "unprognostic (2.39e-1)" "unprognostic (2.61e-1)" "unprognostic (3.39e-1)" "unprognostic (2.94e-1)" "unprognostic (1.57e-1)" "unprognostic (3.53e-1)" EIF5A2 ENSG00000163577 "Eukaryotic translation initiation factor 5A2" Q9GZV4 3 170888418-170908644 "Predicted intracellular proteins, Transporters" "Protein biosynthesis" "Elongation factor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 26.8" "Cell type enhanced" "Detected in many" "Early spermatids: 379.9;Late primary spermatocytes: 187.0;Late spermatids: 1292.1;Parietal cells: 242.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Liver - Vascular endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Parietal cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029090 Approved Supported Vesicles NA NA "Cluster 1: T-cells - Unknown function" "Cluster 57: Testis - Spermatogenesis" "Cluster 45: Non-specific - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 14 Vesicles "HPA029090: " "unprognostic (1.52e-1)" "unprognostic (2.15e-1)" "unprognostic (4.92e-2)" "unprognostic (1.52e-1)" "unprognostic (3.42e-1)" "unprognostic (1.71e-1)" "unprognostic (1.44e-1)" "unprognostic (7.08e-3)" "unprognostic (1.98e-3)" "potential prognostic unfavorable (4.85e-4)" "unprognostic (7.70e-2)" "unprognostic (3.56e-2)" "unprognostic (1.17e-1)" "unprognostic (2.02e-3)" "unprognostic (6.06e-2)" "unprognostic (1.61e-2)" "unprognostic (4.10e-2)" "unprognostic (2.41e-1)" "unprognostic (1.86e-1)" "unprognostic (6.56e-3)" "unprognostic (1.41e-2)" "unprognostic (2.58e-2)" "unprognostic (1.62e-3)" "unprognostic (2.74e-1)" "unprognostic (8.03e-2)" "unprognostic (2.90e-1)" "unprognostic (1.66e-1)" "unprognostic (6.59e-2)" "unprognostic (1.31e-1)" "unprognostic (5.87e-3)" "unprognostic (5.42e-2)" EIF5AL1 "bA342M3.3, EIF5AP1" ENSG00000253626 "Eukaryotic translation initiation factor 5A like 1" Q6IS14 10 79512533-79516440 "Essential proteins, Predicted intracellular proteins, Transporters" "Protein biosynthesis" "Elongation factor, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "testis: 9.9" "Cell type enhanced" "Detected in many" "Colonocytes: 35.6;Enteric stem cells: 36.1;Enteric transient amplifying cells: 44.6;Esophageal basal cells: 34.1;Esophageal suprabasal cells: 27.2;Foveolar cells: 26.4;Goblet cells: 35.6;Late primary spermatocytes: 62.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Testis - Early spermatids" HPA074052 Approved "Plasma membrane,Cytosol" NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 67: Testis - Mixed function" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 61: BICR 18 - Protein kinases" "Cluster 15: Non-specific - Protein processing" 1 Cytosol "Plasma membrane" "HPA074052: " "unprognostic (3.88e-2)" "unprognostic (5.10e-3)" "unprognostic (3.57e-3)" "unprognostic (1.82e-3)" "unprognostic (1.90e-2)" "unprognostic (7.90e-2)" "unprognostic (3.89e-3)" "unprognostic (2.10e-1)" "unprognostic (1.04e-2)" "unprognostic (2.21e-3)" "unprognostic (4.28e-2)" "unprognostic (3.45e-1)" "unprognostic (9.90e-3)" "unprognostic (3.51e-2)" "unprognostic (6.12e-2)" "unprognostic (1.17e-2)" "unprognostic (1.22e-1)" "unprognostic (3.05e-1)" "unprognostic (6.50e-2)" "unprognostic (1.66e-1)" "unprognostic (2.44e-1)" "unprognostic (5.93e-3)" EIF5B "DKFZp434I036, FLJ10524, IF2, KIAA0741" ENSG00000158417 "Eukaryotic translation initiation factor 5B" O60841 2 99337371-99401326 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Hydrolase, Initiation factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early primary spermatocytes: 751.1;Early spermatids: 752.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034648, HPA040095" Approved Approved "Plasma membrane,Cytosol" NA Yes 130000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 17: Non-specific - RNA processing" 16 Cytosol "Plasma membrane" "HPA034648: , HPA040095: " "unprognostic (2.35e-1)" "unprognostic (8.41e-2)" "unprognostic (1.94e-1)" "unprognostic (2.92e-1)" "unprognostic (8.14e-2)" "unprognostic (2.40e-2)" "unprognostic (2.64e-2)" "unprognostic (2.58e-2)" "unprognostic (1.02e-2)" "unprognostic (1.49e-3)" "unprognostic (3.98e-1)" "unprognostic (2.77e-2)" "unprognostic (1.87e-2)" "potential prognostic unfavorable (8.54e-11)" "unprognostic (3.49e-3)" "potential prognostic unfavorable (6.92e-4)" "unprognostic (4.93e-2)" "unprognostic (2.38e-3)" "unprognostic (7.31e-2)" "unprognostic (2.82e-2)" "unprognostic (4.45e-2)" "unprognostic (5.74e-3)" "potential prognostic unfavorable (7.18e-4)" "unprognostic (2.50e-1)" "unprognostic (4.55e-1)" "unprognostic (4.10e-2)" "unprognostic (1.25e-2)" "unprognostic (1.89e-1)" "unprognostic (3.83e-2)" "unprognostic (2.27e-1)" "unprognostic (3.10e-1)" EIF6 "b(2)gcn, EIF3A, ITGB4BP, p27BBP" ENSG00000242372 "Eukaryotic translation initiation factor 6" P56537 20 35278907-35284985 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis, Ribosome biogenesis" "Initiation factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 184.9;Esophageal apical cells: 314.0;Esophageal suprabasal cells: 203.5;Gastric progenitor cells: 191.0;Suprabasal keratinocytes: 258.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040873 Enhanced Supported Nucleoplasm NA NA 650000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 62: Non-specific - Plasma proteins" "Cluster 26: Keratinocytes - Keratinization" 53 Nucleoplasm "HPA040873: " "unprognostic (2.14e-2)" "unprognostic (2.52e-1)" "unprognostic (1.02e-1)" "unprognostic (1.72e-2)" "unprognostic (1.36e-1)" "unprognostic (3.51e-1)" "unprognostic (1.16e-1)" "unprognostic (1.48e-1)" "unprognostic (6.89e-2)" "unprognostic (4.80e-2)" "unprognostic (3.19e-3)" "unprognostic (9.52e-2)" "unprognostic (5.11e-2)" "validated prognostic unfavorable (1.21e-5)" "validated prognostic unfavorable (7.14e-5)" "potential prognostic unfavorable (3.72e-4)" "unprognostic (5.32e-3)" "unprognostic (2.06e-1)" "unprognostic (6.02e-2)" "unprognostic (1.46e-1)" "unprognostic (2.82e-1)" "unprognostic (4.72e-3)" "unprognostic (2.84e-1)" "unprognostic (1.51e-1)" "unprognostic (2.70e-2)" "unprognostic (9.25e-2)" "unprognostic (1.61e-1)" "unprognostic (1.52e-1)" "unprognostic (1.94e-1)" "unprognostic (1.46e-1)" "unprognostic (2.35e-1)" EIPR1 "EIPR-1, TSSC1" ENSG00000032389 "EARP complex and GARP complex interacting protein 1" Q53HC9 2 3188925-3377830 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031231, HPA031232, HPA031233, HPA031234" Approved Supported "Nucleoplasm,Nucleoli,Intermediate filaments" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 14: Neurons - Synaptic function" "Cluster 6: Leukemia - Signal transduction" "Cluster 7: Non-specific - Transcription" 37 "Nucleoplasm, Nucleoli" "Intermediate filaments" "HPA031231: , HPA031232: , HPA031233: , HPA031234: " "unprognostic (3.25e-2)" "unprognostic (2.78e-1)" "unprognostic (1.09e-1)" "unprognostic (3.09e-1)" "unprognostic (6.81e-2)" "unprognostic (2.57e-2)" "potential prognostic favorable (1.50e-5)" "unprognostic (7.59e-2)" "unprognostic (3.46e-1)" "unprognostic (5.42e-2)" "unprognostic (1.75e-2)" "unprognostic (2.12e-1)" "potential prognostic unfavorable (2.31e-7)" "unprognostic (9.10e-3)" "unprognostic (2.75e-2)" "potential prognostic favorable (7.08e-4)" "unprognostic (2.51e-1)" "unprognostic (1.38e-1)" "unprognostic (1.46e-1)" "unprognostic (1.30e-1)" "unprognostic (6.20e-2)" "unprognostic (8.50e-2)" "unprognostic (1.05e-1)" "unprognostic (1.19e-2)" "unprognostic (1.86e-1)" "unprognostic (1.12e-2)" "unprognostic (1.42e-1)" "unprognostic (4.43e-2)" "unprognostic (7.87e-2)" ELAC1 D29 ENSG00000141642 "ElaC ribonuclease Z 1" Q9H777 18 50967991-50988121 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 1.2;Conjunctival goblet cells: 2.9;Early spermatids: 2.0;Late spermatids: 2.7;Medullary thymic epithelial cells: 2.4;pDCs: 1.9" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040867, HPA066483" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 22: Epididymis - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 13: Non-specific - Mixed function" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" Nucleoplasm Cytosol "HPA040867: , HPA066483: " "unprognostic (2.98e-1)" "unprognostic (3.39e-2)" "unprognostic (6.24e-2)" "unprognostic (5.70e-2)" "potential prognostic favorable (3.75e-4)" "unprognostic (6.42e-2)" "unprognostic (2.76e-2)" "unprognostic (2.21e-2)" "unprognostic (4.73e-2)" "unprognostic (2.68e-2)" "potential prognostic favorable (9.97e-5)" "unprognostic (1.18e-2)" "unprognostic (1.01e-3)" "unprognostic (5.82e-2)" "unprognostic (1.96e-1)" "unprognostic (4.79e-2)" "unprognostic (1.30e-1)" "unprognostic (4.66e-2)" "unprognostic (3.81e-2)" "unprognostic (2.49e-3)" "unprognostic (4.09e-1)" "potential prognostic favorable (3.59e-4)" "unprognostic (7.05e-2)" "unprognostic (8.82e-2)" "unprognostic (3.57e-1)" "unprognostic (5.14e-2)" "unprognostic (6.85e-2)" "unprognostic (1.63e-1)" "unprognostic (6.04e-2)" "unprognostic (4.88e-2)" "unprognostic (2.82e-2)" ELAC2 "FLJ10530, HPC2" ENSG00000006744 "ElaC ribonuclease Z 2" Q9BQ52 17 12991612-13018065 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "Endonuclease, Hydrolase, Nuclease" "Disease variant, Primary mitochondrial disease, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 75.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "testis cancer: 363.3" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019535 Approved Supported Nucleoplasm NA NA 3700 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 26 Nucleoplasm "HPA019535: " "unprognostic (7.11e-3)" "unprognostic (2.73e-3)" "unprognostic (3.72e-2)" "unprognostic (3.84e-2)" "unprognostic (2.89e-2)" "unprognostic (4.96e-2)" "unprognostic (2.67e-1)" "unprognostic (2.17e-2)" "unprognostic (1.87e-1)" "unprognostic (3.48e-2)" "potential prognostic favorable (9.26e-4)" "unprognostic (1.62e-1)" "unprognostic (3.96e-2)" "unprognostic (2.16e-1)" "unprognostic (2.72e-1)" "unprognostic (1.66e-1)" "unprognostic (1.71e-1)" "unprognostic (1.09e-1)" "unprognostic (1.52e-1)" "unprognostic (1.19e-1)" "unprognostic (5.93e-2)" "unprognostic (5.96e-2)" "unprognostic (3.74e-2)" "unprognostic (1.59e-1)" "unprognostic (1.54e-1)" "unprognostic (1.11e-1)" "unprognostic (5.87e-2)" "unprognostic (1.94e-1)" "unprognostic (7.31e-2)" "unprognostic (8.58e-2)" "unprognostic (1.19e-1)" ELANE "ELA2, HLE, HNE, NE, PMN-E" ENSG00000197561 "Elastase, neutrophil expressed" P08246 19 851014-856247 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 87 "bone marrow: 3672.0" "Group enriched" "Detected in some" 29 "Monocyte progenitors: 552.5;Neutrophil progenitors: 524.5" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "Pancreatic Adenocarcinoma (TCGA): 5.4;Stomach Adenocarcinoma (TCGA): 7.9" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "classical monocyte: 4.0;neutrophil: 12.2" "Group enriched" "Detected in many" 9 "granulocytes: 12.2;monocytes: 4.0" "Cancer enriched" "Detected in some" 227 "Leukemia: 236.6" "Lung - Neutrophils_1, Pituitary gland - Neutrophils, Skin - Fibroblasts_2, Spleen - Neutrophils_1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB015409, HPA066836, HPA073774" Enhanced Supported "Golgi apparatus,Vesicles" "Secreted to blood" Enzyme NA NA 157000000 3000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 15: Bone marrow - Innate immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 4 Vesicles "Golgi apparatus" "CAB015409: , HPA066836: , HPA073774: " "unprognostic (1.95e-1)" "unprognostic (2.50e-1)" "unprognostic (1.86e-2)" ELAPOR1 "EIG121, KIAA1324, maba1" ENSG00000116299 "Endosome-lysosome associated apoptosis and autophagy regulator 1" Q6UXG2 1 109113679-109206781 "Predicted intracellular proteins, Predicted membrane proteins" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 147.7;salivary gland: 156.2;stomach 1: 83.2" "Cell type enhanced" "Detected in many" "Corticotrophs: 466.9;Goblet cells: 332.0;Gonadotrophs: 313.6;Lacrimal acinar cells: 485.5;Lactotrophs: 452.9;Mucous neck cells: 297.6;Pancreatic islet cells: 392.9;Paneth cells: 506.6;Prostatic glandular cells: 738.4;Salivary acinar cells: 524.0;Somatotrophs: 379.1;Thyrotrophs: 360.2;Tuft cells: 299.7" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 79.6;Prostate Adenocarcinoma (TCGA): 78.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 65.7" "Lineage enriched" "Detected in many" 7 "granulocytes: 65.7" "Cancer enhanced" "Detected in many" "breast cancer: 34.8" "Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Stomach - Chief cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA029869, HPA070749" Enhanced Supported "Plasma membrane" NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 82: Salivary gland - Secretion" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 70: Intestinal goblet cells - Mucin production" "Plasma membrane" "HPA029869: , HPA070749: " "unprognostic (3.13e-1)" "unprognostic (6.59e-2)" "unprognostic (5.86e-2)" "unprognostic (1.33e-2)" "unprognostic (1.73e-1)" "unprognostic (1.21e-1)" "unprognostic (3.98e-2)" "potential prognostic favorable (2.59e-4)" "unprognostic (2.47e-1)" "unprognostic (5.54e-2)" "unprognostic (3.67e-3)" "unprognostic (8.38e-3)" "unprognostic (8.89e-2)" "unprognostic (4.25e-2)" "unprognostic (1.33e-2)" "unprognostic (2.53e-1)" "unprognostic (3.98e-3)" "potential prognostic unfavorable (7.10e-4)" "unprognostic (1.79e-1)" "unprognostic (2.79e-1)" "unprognostic (7.22e-2)" "unprognostic (4.20e-2)" ELAPOR2 "EIG121L, FLJ31340, KIAA1324L" ENSG00000164659 "Endosome-lysosome associated apoptosis and autophagy regulator family member 2" A8MWY0 7 86876906-87059654 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 20.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 298.1;Corticotrophs: 217.9;Lactotrophs: 240.1;Late spermatids: 147.9;Oligodendrocytes: 362.8;Somatotrophs: 159.6;Thyrotrophs: 164.9" "Cell type enhanced" "Detected in all" "oligodendrocyte: 511.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 5 "B-cells: 1.9;NK-cells: 2.3;T-cells: 2.7" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044527, HPA076093" Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 80: Oligodendrocytes - Myelination" 3 "Endoplasmic reticulum" "HPA044527: , HPA076093: " "unprognostic (5.20e-2)" "unprognostic (1.49e-1)" "unprognostic (1.86e-2)" "unprognostic (3.59e-1)" "unprognostic (2.58e-1)" "unprognostic (2.57e-1)" "potential prognostic favorable (5.18e-4)" "unprognostic (2.69e-1)" "unprognostic (6.47e-2)" "unprognostic (2.13e-3)" "potential prognostic favorable (2.38e-4)" "unprognostic (5.49e-3)" "unprognostic (2.48e-2)" "unprognostic (7.37e-2)" "unprognostic (1.21e-1)" "unprognostic (2.57e-3)" "unprognostic (9.79e-2)" "unprognostic (2.28e-2)" "unprognostic (4.88e-2)" "unprognostic (4.89e-2)" "unprognostic (3.47e-1)" "unprognostic (2.36e-2)" "unprognostic (3.73e-1)" "unprognostic (5.49e-2)" "unprognostic (7.34e-3)" "unprognostic (3.57e-1)" "unprognostic (1.62e-1)" "unprognostic (3.20e-3)" ELAVL1 "Hua, HUR, MelG" ENSG00000066044 "ELAV like RNA binding protein 1" Q15717 19 7958573-8005659 "Plasma proteins, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 250.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005256, HPA046298" Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA 15000 "Cluster 45: Eosinophils - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 14: Neurons - Synaptic function" "Cluster 23: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 197 Nucleoplasm "Nucleoli, Cytosol" "CAB005256: , HPA046298: " "unprognostic (4.69e-1)" "unprognostic (1.38e-1)" "unprognostic (1.34e-1)" "unprognostic (1.60e-1)" "unprognostic (3.45e-2)" "unprognostic (1.57e-1)" "unprognostic (1.35e-1)" "unprognostic (1.21e-1)" "unprognostic (3.45e-2)" "unprognostic (1.39e-1)" "potential prognostic favorable (7.44e-6)" "unprognostic (1.69e-1)" "unprognostic (2.08e-1)" "unprognostic (8.62e-3)" "unprognostic (3.91e-3)" "unprognostic (1.69e-2)" "potential prognostic unfavorable (2.03e-4)" "unprognostic (5.24e-1)" "unprognostic (1.91e-2)" "unprognostic (2.39e-2)" "unprognostic (1.17e-1)" "unprognostic (7.83e-3)" "unprognostic (5.96e-2)" "unprognostic (1.38e-2)" "unprognostic (1.01e-1)" "unprognostic (3.59e-2)" "unprognostic (6.56e-2)" "unprognostic (2.64e-1)" "unprognostic (1.30e-1)" "unprognostic (1.52e-1)" "unprognostic (1.75e-1)" ELAVL2 "HEL-N1, HuB" ENSG00000107105 "ELAV like RNA binding protein 2" Q12926 9 23690104-23826337 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 22.3;testis: 40.3" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 128.9;Brain inhibitory neurons: 159.8;Corticotrophs: 104.4;Differentiating spermatogonia: 186.6;Granulosa cells: 63.3;Late primary spermatocytes: 89.5;Oocytes: 202.6;Other brain neurons: 353.3;Retinal ganglion cells: 251.1;Undifferentiated spermatogonia: 269.9" "Cell type enhanced" "Detected in all" "mammillary body: 559.3;MGE interneuron: 708.9" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 10.5;Testicular Germ Cell Tumor (TCGA): 17.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Neuroblastoma: 23.2" "Skin - Outer root sheath cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022222, HPA063001" Enhanced Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 12 Nucleoplasm Cytosol "CAB022222: , HPA063001: " "unprognostic (1.80e-1)" "unprognostic (2.49e-1)" "unprognostic (9.90e-2)" "unprognostic (3.16e-2)" "unprognostic (1.29e-2)" "unprognostic (2.33e-1)" "potential prognostic favorable (3.76e-4)" "unprognostic (2.72e-1)" "unprognostic (1.36e-1)" "unprognostic (1.13e-1)" "unprognostic (3.95e-1)" "unprognostic (2.82e-1)" "unprognostic (5.06e-2)" "unprognostic (2.28e-2)" "unprognostic (1.73e-3)" ELAVL3 "DKFZp547J036, HUC, HUCL, MGC20653, PLE21" ENSG00000196361 "ELAV like RNA binding protein 3" Q14576 19 11451326-11481046 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 26 "brain: 145.3" "Group enriched" "Detected in some" 7 "Astrocytes: 40.7;Bergmann glia: 46.1;Brain excitatory neurons: 133.2;Brain inhibitory neurons: 104.7;Gonadotrophs: 63.8;Oligodendrocyte progenitor cells: 64.9;Oligodendrocytes: 158.1;Other brain neurons: 98.2;Retinal amacrine cells: 141.5;Retinal ganglion cells: 112.0" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in some" 8 "Glioblastoma Multiforme (TCGA): 22.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "Neuroblastoma: 88.2" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pituitary gland - Gonadotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB013066 Enhanced NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 37: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 11 "CAB013066: " "unprognostic (2.18e-1)" "unprognostic (2.04e-2)" "unprognostic (1.56e-2)" "unprognostic (2.70e-1)" ELAVL4 "HUD, PNEM" ENSG00000162374 "ELAV like RNA binding protein 4" P26378 1 50024029-50203772 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 10.5;brain: 38.1" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 382.9;Brain excitatory neurons: 105.4;Brain inhibitory neurons: 93.7;Corticotrophs: 171.8;Early spermatids: 251.0;Lactotrophs: 91.2;Late primary spermatocytes: 104.8;Late spermatids: 346.0;Oligodendrocyte progenitor cells: 103.2;Other brain neurons: 153.8;Pancreatic islet cells: 119.6;Retinal ganglion cells: 123.6;Thyrotrophs: 211.0" "Cell type enhanced" "Detected in all" "lower rhombic lip: 507.2" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 9.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.2" "Lineage enriched" "Detected in single" 5 "monocytes: 1.2" "Cancer enriched" "Detected in some" 18 "Neuroblastoma: 135.7" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004442, HPA043047" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 24: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 2 "Nucleoplasm, Vesicles" "CAB004442: , HPA043047: " "unprognostic (1.10e-1)" "unprognostic (1.43e-3)" "unprognostic (1.16e-1)" "unprognostic (4.36e-3)" "unprognostic (1.64e-1)" "unprognostic (5.23e-2)" ELF1 ENSG00000120690 "E74 like ETS transcription factor 1" P32519 13 40931924-41061440 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 189.8" "Cell type enhanced" "Detected in all" "Neutrophils: 1903.9" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 420.3;endothelial cell: 381.7;leukocyte: 531.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001755, CAB005172" Enhanced Supported Nucleoplasm NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 30: White matter - Myelination" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 7 Nucleoplasm "CAB005172: , HPA001755: " "unprognostic (1.21e-1)" "unprognostic (1.69e-1)" "unprognostic (4.45e-1)" "unprognostic (1.06e-2)" "unprognostic (9.63e-2)" "unprognostic (2.30e-2)" "unprognostic (8.30e-2)" "unprognostic (3.40e-1)" "unprognostic (1.04e-1)" "unprognostic (8.47e-2)" "potential prognostic favorable (3.27e-10)" "unprognostic (6.38e-3)" "unprognostic (3.40e-1)" "unprognostic (3.48e-1)" "unprognostic (1.43e-1)" "unprognostic (3.16e-1)" "unprognostic (3.19e-2)" "unprognostic (5.01e-2)" "unprognostic (6.21e-2)" "unprognostic (1.12e-2)" "unprognostic (3.04e-3)" "unprognostic (9.30e-3)" "unprognostic (4.02e-2)" "unprognostic (3.68e-2)" "unprognostic (2.50e-1)" "unprognostic (4.03e-2)" "unprognostic (2.25e-1)" "unprognostic (3.24e-1)" "unprognostic (1.95e-1)" "unprognostic (2.75e-1)" "unprognostic (2.27e-1)" ELF2 "EU32, NERF, NERF-1A, NERF-1B, NERF-2" ENSG00000109381 "E74 like ETS transcription factor 2" Q15723 4 139028112-139177218 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 5 "Neutrophils: 4633.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "HPA006057, HPA071166" Enhanced Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 10 Nucleoplasm "Nuclear bodies" "HPA006057: , HPA071166: " "unprognostic (8.85e-2)" "unprognostic (1.37e-1)" "unprognostic (3.18e-1)" "unprognostic (1.41e-1)" "unprognostic (1.67e-1)" "unprognostic (1.20e-1)" "unprognostic (2.49e-1)" "unprognostic (8.39e-2)" "unprognostic (2.47e-2)" "unprognostic (3.20e-1)" "validated prognostic favorable (6.79e-6)" "validated prognostic favorable (1.04e-5)" "unprognostic (1.00e-1)" "unprognostic (2.02e-1)" "unprognostic (4.19e-1)" "unprognostic (2.72e-2)" "unprognostic (1.84e-1)" "unprognostic (3.10e-1)" "unprognostic (3.02e-1)" "unprognostic (3.30e-2)" "unprognostic (3.71e-2)" "unprognostic (1.06e-1)" "unprognostic (3.58e-2)" "unprognostic (4.60e-2)" "unprognostic (1.29e-1)" "unprognostic (3.08e-2)" "unprognostic (7.91e-2)" "unprognostic (1.57e-1)" "unprognostic (1.49e-1)" "unprognostic (5.20e-2)" "unprognostic (9.84e-2)" ELF3 "EPR-1, ERT, ESE-1, ESX" ENSG00000163435 "E74 like ETS transcription factor 3" P78545 1 202007945-202017183 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Inflammatory response, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 229.3" "Cell type enhanced" "Detected in many" "Colonocytes: 1283.5;Endometrial glandular cells: 1004.6;Esophageal apical cells: 4004.9;Foveolar cells: 957.8;Goblet cells: 1187.3;Prostatic club cells: 1509.8;Prostatic hillock cells: 1267.1;Urothelial cells: 1275.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Prostate - Urothelial cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Region enhanced" "Detected in single" "basal ganglia: 1.1" "HPA003316, HPA003479" Enhanced Enhanced Nucleoplasm NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 84: Apical squamous epithelium - Cornification" 12 Nucleoplasm "HPA003316: , HPA003479: " "unprognostic (1.89e-3)" "unprognostic (3.13e-2)" "unprognostic (1.15e-1)" "unprognostic (1.90e-1)" "unprognostic (1.66e-2)" "unprognostic (1.44e-1)" "unprognostic (1.13e-1)" "unprognostic (2.50e-1)" "unprognostic (4.98e-1)" "unprognostic (1.65e-1)" "unprognostic (2.18e-2)" "unprognostic (1.39e-2)" "unprognostic (6.23e-2)" "unprognostic (4.38e-1)" "unprognostic (2.20e-2)" "unprognostic (7.98e-2)" "unprognostic (4.00e-2)" "unprognostic (2.35e-3)" "unprognostic (4.20e-2)" "unprognostic (9.25e-3)" "unprognostic (2.97e-1)" "unprognostic (5.25e-2)" "unprognostic (9.50e-2)" "unprognostic (1.56e-1)" "unprognostic (1.54e-1)" "unprognostic (1.78e-2)" "unprognostic (7.74e-2)" "unprognostic (4.10e-1)" "unprognostic (5.54e-2)" ELF4 "ELFR, MEF" ENSG00000102034 "E74 like ETS transcription factor 4" Q99607 X 130063955-130110716 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 50.1" "Cell type enhanced" "Detected in many" "Epicardial cells: 77.3;Extravillous trophoblasts: 61.8;Neutrophil progenitors: 81.4;Neutrophils: 130.8;Urothelial cells: 112.8" "Group enriched" "Detected in some" 5 "central nervous system macrophage: 28.6;leukocyte: 41.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Breast - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Gastric mucous cells, Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA058595, HPA060277" Enhanced Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 15: Bone marrow - Innate immune response" "Cluster 6: Non-specific - Immune response" "Cluster 36: Non-specific - mRNA processing" "Cluster 69: Urothelial cells - Basic cellular functions" 3 "Nuclear bodies" Nucleoplasm "HPA058595: , HPA060277: " "unprognostic (2.46e-1)" "unprognostic (3.04e-1)" "unprognostic (3.66e-2)" "unprognostic (6.35e-2)" "unprognostic (1.36e-1)" "unprognostic (1.47e-1)" "unprognostic (1.93e-2)" "unprognostic (4.22e-2)" "unprognostic (1.07e-1)" "unprognostic (1.77e-2)" "unprognostic (3.19e-2)" "unprognostic (2.71e-1)" "unprognostic (3.19e-3)" "unprognostic (3.22e-3)" "unprognostic (6.93e-2)" "unprognostic (3.14e-2)" "unprognostic (8.73e-3)" "unprognostic (1.98e-1)" "unprognostic (5.15e-1)" "unprognostic (9.40e-2)" "unprognostic (2.40e-1)" "unprognostic (1.93e-2)" "unprognostic (2.10e-1)" "unprognostic (2.86e-1)" "unprognostic (4.11e-2)" "unprognostic (2.34e-1)" "unprognostic (1.63e-2)" "unprognostic (1.28e-1)" "unprognostic (6.22e-2)" "unprognostic (2.50e-1)" "unprognostic (2.64e-2)" ELF5 ENSG00000135374 "E74 like ETS transcription factor 5" Q9UKW6 11 34478791-34525193 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "breast: 140.5;salivary gland: 138.9" "Cell type enriched" "Detected in some" 5 "Breast lactating cells: 1231.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 25.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Bile duct cancer: 18.5;breast cancer: 23.5" "Kidney - Ascending Loop of Henle cells, Minor Salivary Gland - Minor salivary glandular cells, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA062706 Approved Nucleoplasm NA NA "Cluster 82: Salivary gland - Secretion" "Cluster 48: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 4: Breast lactating luminal cells - Lactation" 5 Nucleoplasm "HPA062706: " "unprognostic (4.80e-2)" "unprognostic (7.08e-2)" "unprognostic (3.28e-2)" "unprognostic (2.33e-3)" "unprognostic (1.91e-1)" "unprognostic (1.46e-1)" "unprognostic (4.11e-2)" "potential prognostic favorable (1.52e-4)" "unprognostic (2.03e-1)" "unprognostic (2.29e-1)" "unprognostic (1.92e-1)" "unprognostic (6.89e-2)" "unprognostic (6.81e-3)" "unprognostic (2.53e-2)" "unprognostic (1.96e-2)" "unprognostic (1.21e-1)" "unprognostic (7.00e-3)" "unprognostic (1.36e-1)" ELFN1 PPP1R28 ENSG00000225968 "Extracellular leucine rich repeat and fibronectin type III domain containing 1" P0C7U0 7 1665745-1747946 "Predicted membrane proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "liver: 13.2" "Cell type enhanced" "Detected in some" "Brain inhibitory neurons: 11.7;Cardiomyocytes: 13.8;Cone photoreceptor cells: 62.1;Early spermatids: 14.8;Hepatocytes: 17.0;Late spermatids: 17.9;Mesothelial cells: 10.2;Other brain neurons: 14.0;Retinal ganglion cells: 23.2;Rod photoreceptor cells: 36.1;Vascular endothelial cells: 11.8" "Cell type enhanced" "Detected in many" "CGE interneuron: 30.9;MGE interneuron: 52.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 10.4;Sarcoma: 14.1" "Colon - Endothelial cells, Liver - Hepatocytes, Minor Salivary Gland - Endothelial cells, Stomach - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA066382 Approved "Nucleoplasm,Cell Junctions" NA NA 29000 "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 6: Leukemia - Signal transduction" "Cluster 79: Photoreceptor cells - Phototransduction" "Nucleoplasm, Cell Junctions" "HPA066382: " "unprognostic (2.60e-3)" "unprognostic (1.84e-1)" "unprognostic (4.14e-1)" "potential prognostic unfavorable (7.43e-4)" "unprognostic (1.34e-1)" "unprognostic (5.25e-3)" "unprognostic (8.94e-2)" "unprognostic (7.11e-2)" "potential prognostic favorable (1.68e-4)" "unprognostic (5.25e-3)" "unprognostic (7.76e-2)" "unprognostic (2.30e-3)" "potential prognostic favorable (6.65e-7)" "unprognostic (6.92e-3)" "unprognostic (7.15e-2)" "unprognostic (1.57e-3)" "unprognostic (1.96e-2)" "unprognostic (6.17e-3)" "unprognostic (3.56e-2)" "unprognostic (3.45e-1)" "unprognostic (6.94e-2)" "unprognostic (5.33e-2)" ELFN2 "dJ63G5.3, KIAA1904, LRRC62, PPP1R29" ENSG00000166897 "Extracellular leucine rich repeat and fibronectin type III domain containing 2" Q5R3F8 22 37367960-37427479 "Predicted membrane proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 17.3;retina: 5.6" "Group enriched" "Detected in some" 4 "Loop of henle epithelial cells: 5.2;Proximal tubule cells: 16.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney Renal Papillary Cell Carcinoma (TCGA): 5.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 21.8" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000781 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 88: Proximal tubular cells - Transmembrane transport" "Nucleoplasm, Vesicles" "HPA000781: " "unprognostic (1.29e-1)" "unprognostic (1.72e-3)" "unprognostic (6.43e-2)" "unprognostic (1.57e-2)" "unprognostic (7.71e-2)" "unprognostic (5.19e-1)" "unprognostic (1.55e-1)" "unprognostic (1.06e-1)" "potential prognostic unfavorable (5.31e-4)" "unprognostic (3.80e-1)" ELK1 ENSG00000126767 "ETS transcription factor ELK1" P19419 X 47635521-47650604 "Predicted intracellular proteins, RAS pathway related proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 145.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003808, HPA036084, HPA064381" Enhanced Enhanced Nucleoplasm NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 65: Brain - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 94: Gonadal somatic cells - Mixed function" 22 Nucleoplasm "CAB003808: , HPA036084: , HPA064381: " "unprognostic (4.84e-2)" "unprognostic (7.00e-2)" "unprognostic (3.35e-1)" "unprognostic (6.56e-2)" "unprognostic (1.68e-1)" "unprognostic (1.47e-1)" "unprognostic (9.54e-2)" "unprognostic (1.96e-1)" "unprognostic (2.90e-1)" "unprognostic (3.12e-2)" "unprognostic (5.89e-3)" "unprognostic (1.54e-1)" "unprognostic (1.18e-2)" "unprognostic (2.06e-2)" "unprognostic (1.00e-3)" "unprognostic (1.06e-2)" "potential prognostic unfavorable (7.49e-4)" "unprognostic (1.89e-1)" "unprognostic (2.63e-1)" "unprognostic (1.50e-1)" "unprognostic (4.15e-1)" "unprognostic (1.01e-1)" "unprognostic (2.50e-1)" "unprognostic (7.74e-2)" "unprognostic (5.34e-2)" "unprognostic (2.03e-3)" "unprognostic (1.31e-1)" "unprognostic (2.29e-1)" "unprognostic (8.74e-2)" "unprognostic (7.18e-2)" "unprognostic (2.66e-1)" ELK3 "ERP, NET, SAP2" ENSG00000111145 "ETS transcription factor ELK3" P41970 12 96194375-96269824 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal basal cells: 278.8;Esophageal apical cells: 300.8;Lymphatic endothelial cells: 469.9;Ocular epithelial cells: 262.8;Platelets: 269.0;Vascular endothelial cells: 298.6" "Group enriched" "Detected in all" 4 "central nervous system macrophage: 160.7;endothelial cell: 173.0;leukocyte: 50.5;upper rhombic lip: 54.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001600 Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 25: Non-specific - Transcription" "Cluster 72: Neuronal - Signal transduction" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 15 Nucleoplasm Mitochondria "HPA001600: " "unprognostic (6.17e-3)" "unprognostic (3.63e-1)" "unprognostic (2.96e-1)" "potential prognostic unfavorable (3.30e-4)" "unprognostic (1.13e-1)" "unprognostic (1.75e-1)" "unprognostic (4.07e-2)" "unprognostic (1.49e-3)" "unprognostic (3.16e-1)" "unprognostic (1.40e-1)" "potential prognostic favorable (1.31e-4)" "unprognostic (3.43e-3)" "unprognostic (4.02e-3)" "unprognostic (1.62e-1)" "unprognostic (7.55e-2)" "unprognostic (6.38e-3)" "unprognostic (5.22e-3)" "unprognostic (1.11e-2)" "unprognostic (2.78e-3)" "potential prognostic unfavorable (1.95e-5)" "unprognostic (2.61e-3)" "unprognostic (8.26e-3)" "unprognostic (2.04e-3)" "unprognostic (3.56e-1)" "unprognostic (2.03e-1)" "unprognostic (1.99e-2)" "unprognostic (7.58e-2)" "potential prognostic unfavorable (1.78e-4)" "unprognostic (3.74e-2)" "unprognostic (2.50e-1)" "unprognostic (2.76e-1)" ELK4 SAP1 ENSG00000158711 "ETS transcription factor ELK4" P28324 1 205597556-205632011 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 165.9;Prostatic glandular cells: 569.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 6.7" "Lineage enriched" "Detected in many" 4 "granulocytes: 6.7" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028863 Uncertain Supported Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 49: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 4 Nucleoplasm "HPA028863: " "unprognostic (2.78e-2)" "unprognostic (7.32e-2)" "unprognostic (1.53e-1)" "unprognostic (2.90e-1)" "unprognostic (9.76e-2)" "unprognostic (1.03e-1)" "unprognostic (1.18e-1)" "unprognostic (1.50e-1)" "unprognostic (7.24e-3)" "unprognostic (4.10e-3)" "potential prognostic favorable (6.18e-4)" "unprognostic (7.77e-3)" "unprognostic (4.40e-3)" "unprognostic (3.52e-1)" "unprognostic (6.37e-2)" "unprognostic (8.73e-2)" "unprognostic (1.63e-1)" "unprognostic (5.24e-2)" "unprognostic (1.03e-1)" "unprognostic (2.25e-1)" "unprognostic (1.75e-3)" "unprognostic (1.28e-2)" "unprognostic (3.58e-2)" "unprognostic (6.68e-2)" "unprognostic (1.66e-1)" "unprognostic (2.12e-2)" "unprognostic (1.52e-1)" "unprognostic (2.09e-1)" "unprognostic (3.31e-1)" "unprognostic (7.96e-3)" "unprognostic (1.21e-1)" ELL "C19orf17, ELL1, Men, PPP1R68" ENSG00000105656 "Elongation factor for RNA polymerase II" P55199 19 18442663-18522116 "Cancer-related genes, Disease related genes, Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 396.1;Late spermatids: 305.3;Neutrophils: 458.2;Syncytiotrophoblasts: 209.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Neutrophils, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004202, HPA046076" Uncertain Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 67: Testis - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 23: Non-specific - Transcription" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 31 Nucleoplasm "Nuclear bodies, Cytosol" "HPA004202: , HPA046076: " "unprognostic (8.83e-3)" "unprognostic (3.26e-1)" "unprognostic (3.11e-1)" "unprognostic (1.84e-3)" "unprognostic (7.77e-2)" "unprognostic (2.25e-1)" "unprognostic (3.75e-2)" "unprognostic (1.04e-1)" "unprognostic (2.45e-1)" "unprognostic (1.74e-1)" "unprognostic (7.21e-2)" "unprognostic (1.14e-1)" "unprognostic (2.16e-1)" "unprognostic (3.62e-2)" "unprognostic (1.22e-1)" "unprognostic (1.29e-1)" "unprognostic (1.90e-1)" "unprognostic (6.71e-2)" "unprognostic (3.41e-2)" "unprognostic (2.26e-2)" "unprognostic (2.87e-1)" "unprognostic (1.15e-1)" "unprognostic (4.68e-2)" "unprognostic (5.68e-2)" "unprognostic (1.85e-1)" "potential prognostic favorable (2.56e-4)" "unprognostic (2.92e-1)" "unprognostic (3.27e-1)" "unprognostic (2.67e-1)" "unprognostic (1.10e-1)" "unprognostic (2.43e-1)" ELL2 MRCCAT1 ENSG00000118985 "Elongation factor for RNA polymerase II 2" O00472 5 95885098-95961851 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Mast cells: 2267.5;monocytes: 1491.8;Myosatellite cells: 1257.0;Neutrophils: 5147.6;Pancreatic acinar cells: 1448.3;Plasma cells: 1499.4;Salivary acinar cells: 1375.7" "Cell type enhanced" "Detected in all" "oligodendrocyte: 567.6;vascular associated smooth muscle cell: 570.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 7.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013569 Supported Nucleoplasm No No "Cluster 22: Eosinophils - Transcription" "Cluster 70: Non-specific - Protein processing" "Cluster 11: White matter - Signal transduction" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 28 Nucleoplasm "HPA013569: " "unprognostic (1.78e-1)" "unprognostic (1.91e-1)" "unprognostic (6.54e-2)" "unprognostic (1.28e-1)" "unprognostic (2.26e-2)" "unprognostic (1.03e-1)" "unprognostic (4.23e-1)" "unprognostic (7.52e-2)" "unprognostic (1.32e-1)" "potential prognostic unfavorable (3.80e-4)" "unprognostic (2.58e-1)" "unprognostic (7.10e-2)" "unprognostic (3.86e-1)" "unprognostic (1.31e-1)" "unprognostic (2.04e-1)" "unprognostic (1.35e-1)" "unprognostic (3.16e-2)" "unprognostic (5.10e-2)" "unprognostic (4.30e-2)" "unprognostic (1.49e-1)" "unprognostic (7.03e-2)" "unprognostic (1.32e-1)" "potential prognostic unfavorable (3.21e-6)" "unprognostic (1.83e-1)" "unprognostic (3.84e-1)" "unprognostic (2.28e-1)" "unprognostic (6.19e-2)" "unprognostic (3.15e-3)" "unprognostic (4.77e-2)" "potential prognostic unfavorable (5.54e-4)" "unprognostic (8.66e-2)" ELL3 FLJ22637 ENSG00000128886 "Elongation factor for RNA polymerase II 3" Q9HB65 15 43772605-43777315 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 54.0;skin 1: 25.0" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 6.9;Colonocytes: 1.3;Enteric stem cells: 1.0;Enteric transient amplifying cells: 1.8;Enterocytes: 2.7;Ependymal cells: 1.2;Goblet cells: 1.2;Parietal cells: 1.8" "Cell type enriched" "Detected in some" 7 "choroid plexus epithelial cell: 10.8" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 8 "choroid plexus: 11.0" "Group enriched" "Detected in some" 4 "memory B-cell: 11.2;naive B-cell: 17.0" "Lineage enriched" "Detected in many" 5 "B-cells: 17.0" "Cancer enriched" "Detected in many" 5 "lymphoma: 72.9" "Lung - Respiratory ciliated cells, Skin - Keratinocyte (other), Testis - Early spermatids" "Region enriched" "Detected in single" 11 "olfactory bulb: 1.9" "Not detected" "Not detected" "HPA028938, HPA073494" Approved Supported "Nucleoplasm,Nucleoli,Mitotic chromosome" Yes NA "Cluster 14: Non-specific - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 36: Choroid plexus - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 11 "Nucleoplasm, Nucleoli" "Mitotic chromosome" "HPA028938: , HPA073494: " "unprognostic (9.95e-2)" "unprognostic (1.78e-2)" "unprognostic (3.92e-1)" "unprognostic (5.64e-2)" "unprognostic (1.34e-2)" "unprognostic (1.53e-2)" "unprognostic (3.34e-2)" "unprognostic (9.38e-2)" "unprognostic (2.52e-2)" "unprognostic (2.32e-1)" "unprognostic (3.06e-2)" "unprognostic (4.29e-2)" "unprognostic (2.39e-1)" "unprognostic (7.39e-2)" "unprognostic (2.16e-1)" "unprognostic (3.18e-1)" "unprognostic (2.54e-1)" "unprognostic (5.36e-2)" "unprognostic (3.29e-1)" "unprognostic (5.70e-2)" "unprognostic (1.27e-2)" "unprognostic (1.03e-1)" ELMO1 "CED-12, CED12, ELMO-1, KIAA0281" ENSG00000155849 "Engulfment and cell motility 1" Q92556 7 36852906-37449223 "Predicted intracellular proteins" "Apoptosis, Phagocytosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 117.5" "Cell type enhanced" "Detected in many" "Hematopoietic stem cells: 4535.4;Macrophages: 957.6;Mast cells: 892.9;Megakaryocyte-Erythroid progenitors: 1805.9;Microglia: 1925.0;Neutrophil progenitors: 1278.2;Neutrophils: 1758.6;Oligodendrocytes: 1828.8;Pituicytes/FSCs: 1100.1;Thymocytes: 1196.7" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 2611.5;oligodendrocyte: 2508.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 70.9;lymphoma: 106.2;Myeloma: 81.9" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Lung - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 59: Leukemia - T-cell receptor" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 29 "unprognostic (1.72e-1)" "unprognostic (1.54e-1)" "unprognostic (2.06e-3)" "unprognostic (4.33e-3)" "unprognostic (1.18e-1)" "unprognostic (7.03e-2)" "unprognostic (7.83e-2)" "potential prognostic favorable (2.04e-4)" "unprognostic (1.51e-1)" "unprognostic (5.25e-2)" "potential prognostic favorable (5.94e-4)" "unprognostic (4.20e-2)" "unprognostic (1.32e-1)" "unprognostic (1.52e-2)" "unprognostic (9.44e-2)" "potential prognostic favorable (6.71e-6)" "unprognostic (5.05e-2)" "unprognostic (9.14e-2)" "unprognostic (1.87e-1)" "unprognostic (1.06e-1)" "unprognostic (3.08e-1)" "potential prognostic favorable (6.60e-4)" "unprognostic (1.30e-1)" "unprognostic (2.60e-1)" "unprognostic (2.67e-2)" "unprognostic (1.01e-2)" "unprognostic (4.47e-2)" "unprognostic (1.11e-2)" "unprognostic (7.76e-2)" "unprognostic (4.34e-3)" "unprognostic (3.43e-1)" ELMO2 "CED-12, CED12, ELMO-2, FLJ11656, KIAA1834" ENSG00000062598 "Engulfment and cell motility 2" Q96JJ3 20 46366050-46432985 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Phagocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 99.8;Neutrophils: 85.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018811 Approved Supported Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 27: Cerebellum - Synaptic function" "Cluster 15: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 10 Cytosol "HPA018811: " "unprognostic (1.16e-1)" "unprognostic (1.23e-2)" "unprognostic (2.25e-1)" "unprognostic (4.91e-2)" "unprognostic (1.50e-1)" "unprognostic (1.79e-1)" "unprognostic (2.28e-1)" "potential prognostic favorable (3.76e-4)" "unprognostic (1.61e-1)" "unprognostic (9.16e-2)" "unprognostic (9.15e-3)" "unprognostic (3.94e-1)" "unprognostic (2.40e-1)" "potential prognostic unfavorable (8.80e-5)" "unprognostic (3.13e-1)" "unprognostic (3.70e-2)" "unprognostic (3.73e-2)" "unprognostic (2.44e-2)" "unprognostic (2.42e-1)" "unprognostic (1.18e-1)" "unprognostic (2.79e-2)" "potential prognostic favorable (6.67e-4)" "unprognostic (2.42e-3)" "unprognostic (1.40e-1)" "unprognostic (5.64e-2)" "unprognostic (1.73e-2)" "unprognostic (3.59e-1)" "unprognostic (2.77e-1)" "unprognostic (2.77e-1)" "unprognostic (8.79e-2)" "unprognostic (8.98e-2)" ELMO3 "CED-12, CED12, ELMO-3, FLJ13824" ENSG00000102890 "Engulfment and cell motility 3" Q96BJ8 16 67199111-67204029 "Predicted intracellular proteins" "Apoptosis, Phagocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast lactating cells: 97.3;Colonocytes: 63.7;Enteric transient amplifying cells: 46.9;Enterocytes: 87.9;Foveolar cells: 45.6;Late spermatids: 67.1" "Cell type enhanced" "Detected in many" "lower rhombic lip: 7.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Pituitary gland - Somatotropes, Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA021484 Approved Approved "Plasma membrane,Cell Junctions" NA NA "Cluster 60: Stomach - Digestion" "Cluster 6: Non-specific - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 97: Non-specific - Cellular respiration" "Plasma membrane, Cell Junctions" "HPA021484: " "unprognostic (4.28e-2)" "unprognostic (2.87e-3)" "unprognostic (1.84e-1)" "unprognostic (3.59e-2)" "unprognostic (1.05e-1)" "unprognostic (1.96e-1)" "unprognostic (2.94e-1)" "unprognostic (2.68e-3)" "unprognostic (3.14e-2)" "unprognostic (1.97e-3)" "unprognostic (4.38e-3)" "unprognostic (1.32e-1)" "potential prognostic favorable (2.32e-4)" "unprognostic (3.23e-1)" "unprognostic (6.67e-3)" "unprognostic (2.14e-1)" "unprognostic (9.73e-2)" "potential prognostic unfavorable (1.22e-4)" "unprognostic (3.45e-1)" "unprognostic (2.74e-2)" "unprognostic (2.48e-1)" "unprognostic (3.68e-2)" "unprognostic (1.66e-1)" "unprognostic (2.88e-2)" "unprognostic (4.55e-2)" "unprognostic (2.55e-1)" "unprognostic (2.20e-1)" "unprognostic (3.11e-1)" "unprognostic (4.68e-1)" "unprognostic (3.44e-1)" "unprognostic (1.44e-1)" ELMOD1 DKFZp547C176 ENSG00000110675 "ELMO domain containing 1" Q8N336 11 107591091-107666779 "Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 51.8;pituitary gland: 20.0;retina: 30.2;skin 1: 27.3" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 135.9;Brain inhibitory neurons: 268.0;Ependymal cells: 68.3;Lactotrophs: 121.1;Oligodendrocyte progenitor cells: 123.7;Other brain neurons: 104.1;Retinal amacrine cells: 99.8;Retinal bipolar cells: 99.3;Retinal horizontal cells: 90.2;Rod photoreceptor cells: 76.9;Somatotrophs: 334.3;Thyrotrophs: 158.4" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in some" 10 "Glioblastoma Multiforme (TCGA): 15.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Rhabdoid: 26.2" "Kidney - Proximal tubular cells, Pituitary gland - Somatotropes, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038434, HPA038435" Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 2: Non-specific - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" 1 Nucleoplasm "Vesicles, Cytosol" "HPA038434: , HPA038435: " "unprognostic (1.53e-2)" "unprognostic (3.96e-2)" "unprognostic (3.14e-1)" "unprognostic (7.65e-3)" "unprognostic (1.04e-2)" "unprognostic (1.72e-1)" "unprognostic (2.99e-3)" "unprognostic (1.91e-1)" "potential prognostic unfavorable (3.78e-4)" ELMOD2 MGC10084 ENSG00000179387 "ELMO domain containing 2" Q8IZ81 4 140524168-140553770 "Predicted intracellular proteins" "Antiviral defense" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041468, HPA047600" Approved Approved "Nucleoplasm,Nuclear bodies,Actin filaments,Cytosol" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 42: Retina - Visual perception" "Cluster 55: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 7: Non-specific - Transcription" 1 "Nuclear bodies, Actin filaments" "Nucleoplasm, Cytosol" "HPA041468: , HPA047600: " "unprognostic (4.81e-1)" "unprognostic (8.35e-2)" "unprognostic (2.59e-1)" "unprognostic (5.73e-2)" "unprognostic (1.60e-2)" "unprognostic (3.39e-2)" "unprognostic (6.77e-2)" "unprognostic (1.29e-2)" "unprognostic (4.07e-1)" "unprognostic (1.12e-2)" "potential prognostic favorable (8.34e-7)" "unprognostic (2.89e-3)" "unprognostic (1.34e-3)" "unprognostic (3.70e-3)" "unprognostic (1.55e-1)" "unprognostic (3.60e-3)" "unprognostic (2.10e-1)" "unprognostic (2.49e-1)" "unprognostic (3.21e-1)" "unprognostic (1.98e-1)" "unprognostic (8.73e-3)" "unprognostic (4.31e-1)" "unprognostic (3.20e-2)" "unprognostic (2.43e-1)" "unprognostic (7.71e-2)" "unprognostic (7.03e-2)" "unprognostic (2.08e-1)" "unprognostic (2.63e-2)" "unprognostic (3.26e-1)" "unprognostic (1.31e-2)" "unprognostic (4.16e-3)" ELMOD3 "DFNB88, FLJ21977, RBED1, RBM29" ENSG00000115459 "ELMO domain containing 3" Q96FG2 2 85354394-85391752 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "GTPase activation" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Adipocytes: 580.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012126 Approved NA NA "Cluster 32: Basophils - Transcription" "Cluster 74: Non-specific - Signal transduction" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 89: Adipocytes - Lipid metabolism" 1 "HPA012126: " "unprognostic (9.04e-2)" "unprognostic (9.98e-3)" "unprognostic (3.75e-1)" "unprognostic (8.09e-2)" "unprognostic (4.41e-2)" "unprognostic (1.01e-1)" "unprognostic (1.19e-1)" "unprognostic (1.02e-2)" "unprognostic (2.18e-1)" "unprognostic (2.35e-1)" "unprognostic (2.75e-3)" "unprognostic (1.31e-1)" "unprognostic (1.40e-1)" "unprognostic (1.90e-2)" "unprognostic (5.90e-2)" "unprognostic (8.26e-2)" "unprognostic (1.53e-1)" "unprognostic (9.20e-2)" "unprognostic (2.27e-1)" "unprognostic (2.68e-2)" "unprognostic (6.89e-2)" "unprognostic (9.54e-3)" "unprognostic (1.63e-3)" "unprognostic (2.53e-1)" "unprognostic (2.85e-2)" "unprognostic (2.53e-1)" "unprognostic (3.19e-1)" "unprognostic (1.30e-1)" "unprognostic (2.31e-1)" "potential prognostic unfavorable (6.52e-4)" "unprognostic (9.59e-2)" ELN "SVAS, WBS, WS" ENSG00000049540 Elastin P15502 7 74027789-74069907 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "blood vessel: 1227.9" "Cell type enhanced" "Detected in many" "Fibro-adipogenic progenitors: 206.8;Fibroblasts: 319.5;Hepatic stellate cells: 568.0;Leydig cells: 233.1;Peritubular myoid cells: 347.1;Thymic myoid cells: 579.2;Vascular smooth muscle cells: 306.8" "Cell type enhanced" "Detected in many" "endothelial cell: 117.7;ependymal cell: 104.3;fibroblast: 136.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Brain cancer: 62.6;Sarcoma: 187.5" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skin - Fibroblasts_2, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010750, HPA018111, HPA056941" Supported Approved "Plasma membrane" "Secreted to extracellular matrix" "No annotated function" NA NA 570000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 6: Non-specific - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 5 "Plasma membrane" "CAB010750: , HPA018111: , HPA056941: " "unprognostic (4.70e-3)" "unprognostic (4.93e-3)" "unprognostic (6.27e-3)" "unprognostic (1.79e-1)" "unprognostic (2.29e-2)" "unprognostic (5.12e-2)" "unprognostic (2.41e-2)" "unprognostic (1.86e-2)" "unprognostic (3.45e-2)" "unprognostic (5.79e-2)" "validated prognostic favorable (2.77e-4)" "validated prognostic favorable (1.73e-4)" "potential prognostic unfavorable (3.82e-8)" "unprognostic (1.93e-2)" "unprognostic (4.46e-3)" "unprognostic (3.45e-2)" "unprognostic (9.90e-2)" "unprognostic (4.94e-3)" "unprognostic (2.20e-1)" "unprognostic (6.52e-3)" "unprognostic (2.12e-2)" "unprognostic (1.12e-1)" "unprognostic (1.46e-2)" "unprognostic (2.46e-1)" "unprognostic (7.50e-2)" "unprognostic (3.45e-2)" "unprognostic (2.33e-2)" "unprognostic (7.22e-3)" "unprognostic (5.72e-2)" "potential prognostic unfavorable (4.29e-4)" "unprognostic (2.94e-1)" ELOA "SIII, TCEB3, TCEB3A" ENSG00000011007 "Elongin A" Q14241 1 23743448-23762059 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005910 Approved Approved "Nuclear speckles,Cytosol" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 55: Breast - Lactation" "Cluster 55: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 61 "Nuclear speckles" Cytosol "HPA005910: " "unprognostic (1.54e-1)" "unprognostic (3.26e-2)" "potential prognostic unfavorable (7.67e-4)" "unprognostic (1.02e-1)" "unprognostic (1.53e-1)" "unprognostic (1.49e-1)" "potential prognostic favorable (7.20e-4)" "unprognostic (1.89e-2)" "potential prognostic unfavorable (9.53e-4)" "potential prognostic favorable (2.43e-5)" "unprognostic (2.56e-2)" "unprognostic (4.92e-2)" "potential prognostic unfavorable (2.02e-6)" "unprognostic (7.82e-2)" "unprognostic (1.06e-1)" "unprognostic (9.32e-2)" "unprognostic (2.29e-1)" "unprognostic (5.71e-2)" "unprognostic (2.55e-1)" "unprognostic (2.82e-1)" "unprognostic (1.21e-1)" "unprognostic (1.37e-2)" "unprognostic (1.96e-1)" "unprognostic (6.61e-2)" "unprognostic (1.42e-1)" "unprognostic (2.58e-1)" "unprognostic (5.11e-1)" "unprognostic (4.05e-2)" "unprognostic (1.44e-1)" ELOA2 "HsT832, TCEB3B, TCEB3L" ENSG00000206181 "Elongin A2" Q8IYF1 18 47032527-47035621 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 38 "testis: 3.8" "Group enriched" "Detected in some" 4 "Early spermatids: 33.7;Late primary spermatocytes: 21.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "HPA041009, HPA043501, HPA048971, HPA049178, HPA050086, HPA053158" Approved Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 6: Non-specific - Immune response" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 11 Nucleoplasm "Nucleoli, Cytosol" "HPA041009: , HPA043501: , HPA048971: , HPA049178: , HPA050086: , HPA053158: " ELOB "SIII, TCEB2" ENSG00000103363 "Elongin B" Q15370 16 2771414-2777289 "Essential proteins, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Late spermatids: 12046.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064006 Approved NA NA 160000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 111 "HPA064006: " "unprognostic (5.12e-2)" "unprognostic (2.06e-1)" "unprognostic (2.07e-3)" "unprognostic (1.31e-1)" "unprognostic (1.42e-1)" "unprognostic (1.03e-1)" "unprognostic (1.44e-1)" "unprognostic (5.58e-3)" "unprognostic (3.09e-1)" "unprognostic (2.84e-3)" "unprognostic (1.68e-3)" "unprognostic (7.06e-2)" "unprognostic (1.15e-2)" "unprognostic (9.24e-3)" "unprognostic (3.65e-2)" "unprognostic (2.58e-1)" "unprognostic (3.40e-1)" "unprognostic (1.60e-1)" "unprognostic (8.84e-2)" "unprognostic (1.58e-1)" "unprognostic (1.19e-1)" "unprognostic (3.86e-2)" "unprognostic (1.14e-1)" "unprognostic (4.36e-2)" "unprognostic (8.61e-2)" "unprognostic (1.37e-1)" "unprognostic (1.41e-1)" "unprognostic (2.09e-1)" "unprognostic (3.58e-2)" ELOC "SIII, TCEB1" ENSG00000154582 "Elongin C" Q15369 8 73939169-73972307 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 636.2;Esophageal apical cells: 992.3;Late primary spermatocytes: 919.2;Late spermatids: 588.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA078113 Approved "Nucleoli,Vesicles,Cell Junctions" NA NA 51000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 103: Non-specific - Basic cellular processes" 112 Vesicles "Nucleoli, Cell Junctions" "HPA078113: " "unprognostic (6.33e-3)" "potential prognostic unfavorable (1.34e-4)" "unprognostic (6.51e-2)" "unprognostic (1.82e-1)" "unprognostic (3.77e-1)" "potential prognostic unfavorable (1.44e-4)" "unprognostic (1.37e-1)" "unprognostic (2.21e-3)" "unprognostic (1.00e-2)" "unprognostic (9.23e-3)" "unprognostic (1.47e-2)" "potential prognostic unfavorable (9.88e-4)" "potential prognostic unfavorable (5.90e-4)" "unprognostic (3.58e-3)" "unprognostic (1.40e-2)" "unprognostic (9.39e-2)" "unprognostic (1.38e-2)" "unprognostic (7.29e-2)" "unprognostic (4.06e-2)" "unprognostic (1.74e-3)" "potential prognostic unfavorable (3.89e-5)" "unprognostic (1.32e-2)" "unprognostic (2.58e-2)" "unprognostic (1.20e-1)" "unprognostic (8.23e-2)" "unprognostic (1.80e-1)" "unprognostic (2.18e-1)" "unprognostic (1.33e-1)" "unprognostic (5.22e-2)" ELOF1 "ELF1, MGC4549" ENSG00000130165 "Elongation factor 1" P60002 19 11551147-11559230 "Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 455.0;Late primary spermatocytes: 643.0;Late spermatids: 2533.2;Oocytes: 414.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045606 Uncertain Approved Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 31: Non-specific - Transcription" "Cluster 23: Non-specific - Transcription" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 2 Cytosol "HPA045606: " "unprognostic (5.75e-3)" "unprognostic (1.65e-1)" "unprognostic (2.15e-1)" "unprognostic (1.65e-1)" "unprognostic (5.64e-3)" "unprognostic (1.34e-1)" "unprognostic (8.85e-2)" "unprognostic (1.51e-1)" "unprognostic (1.95e-1)" "unprognostic (1.30e-2)" "unprognostic (1.85e-1)" "unprognostic (2.72e-1)" "unprognostic (1.79e-1)" "potential prognostic unfavorable (6.88e-5)" "unprognostic (7.47e-2)" "unprognostic (9.78e-2)" "unprognostic (2.79e-2)" "unprognostic (6.63e-3)" "unprognostic (2.60e-2)" "unprognostic (3.85e-2)" "unprognostic (2.46e-1)" "unprognostic (7.03e-2)" "unprognostic (4.05e-1)" "unprognostic (5.08e-2)" "unprognostic (2.05e-2)" "unprognostic (1.59e-1)" "unprognostic (5.22e-2)" "unprognostic (1.27e-2)" "unprognostic (9.79e-2)" "unprognostic (2.15e-1)" "unprognostic (2.75e-1)" ELOVL1 Ssc1 ENSG00000066322 "ELOVL fatty acid elongase 1" Q9BW60 1 43363398-43368074 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 357.2" "Cell type enhanced" "Detected in many" "Breast lactating cells: 316.0;Esophageal apical cells: 589.3;Esophageal suprabasal cells: 270.3;Extravillous trophoblasts: 164.0" "Group enriched" "Detected in all" 4 "committed oligodendrocyte precursor: 45.5;oligodendrocyte: 135.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Adrenal cortex cells, Skin - Keratinocyte (granular), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033426, HPA056557" Enhanced Supported "Endoplasmic reticulum" NA Yes 110000 "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 37: Non-specific - mRNA processing" "Cluster 85: Squamous epithelial cells - Keratinization" 15 "Endoplasmic reticulum" "CAB033426: , HPA056557: " "unprognostic (4.10e-2)" "unprognostic (2.45e-2)" "unprognostic (1.65e-1)" "potential prognostic unfavorable (1.88e-4)" "unprognostic (6.30e-2)" "unprognostic (3.69e-3)" "unprognostic (1.37e-2)" "unprognostic (1.63e-2)" "unprognostic (1.81e-1)" "unprognostic (6.88e-3)" "unprognostic (2.39e-3)" "unprognostic (8.54e-2)" "unprognostic (2.02e-1)" "potential prognostic unfavorable (5.95e-8)" "unprognostic (5.65e-3)" "unprognostic (1.61e-1)" "unprognostic (1.32e-1)" "unprognostic (6.95e-2)" "unprognostic (2.81e-2)" "unprognostic (2.45e-1)" "unprognostic (2.39e-1)" "potential prognostic unfavorable (4.59e-4)" "unprognostic (1.18e-1)" "unprognostic (3.37e-1)" "unprognostic (9.71e-2)" "unprognostic (1.02e-1)" "unprognostic (1.05e-1)" "unprognostic (7.88e-2)" "unprognostic (1.28e-1)" "unprognostic (5.17e-2)" "unprognostic (1.06e-1)" ELOVL2 Ssc2 ENSG00000197977 "ELOVL fatty acid elongase 2" Q9NXB9 6 10980759-11044305 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.3;liver: 49.1;placenta: 33.1;retina: 25.8" "Cell type enhanced" "Detected in many" "Astrocytes: 129.2;Bergmann glia: 278.5;Cone photoreceptor cells: 161.5;Epicardial cells: 293.4;Oocytes: 271.7;Pituicytes/FSCs: 127.7;Rod photoreceptor cells: 68.2;Sertoli cells: 90.2" "Group enriched" "Detected in all" 6 "astrocyte: 118.6;Bergmann glia: 348.1" "Group enriched" "Detected in many" 8 "Breast Invasive Carcinoma (TCGA): 18.2;Glioblastoma Multiforme (TCGA): 41.7;Liver Hepatocellular Carcinoma (TCGA): 29.4;Prostate Adenocarcinoma (TCGA): 13.2;Skin Cutaneous Melanoma (TCGA): 22.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 26.9" "Breast - Breast glandular cells, Colon - Enteric glia cells, Liver - Hepatocytes, Lung - Fibroblasts_2, Pituitary gland - Undifferentiated cells (Pituitary gland), Prostate - Prostate glandular cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 27: Breast cancer - Unknown function" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 6 "potential prognostic favorable (3.02e-4)" "unprognostic (1.96e-1)" "unprognostic (3.33e-2)" "potential prognostic unfavorable (1.78e-4)" "unprognostic (5.49e-3)" "unprognostic (9.60e-2)" "unprognostic (6.91e-2)" "unprognostic (1.81e-2)" "unprognostic (3.14e-1)" "unprognostic (3.17e-1)" "unprognostic (2.74e-2)" "potential prognostic favorable (9.85e-4)" "unprognostic (7.69e-3)" "unprognostic (2.02e-2)" "unprognostic (9.13e-2)" ELOVL3 CIG-30 ENSG00000119915 "ELOVL fatty acid elongase 3" Q9HB03 10 102226299-102229589 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skin 1: 28.1" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 4.3;Breast secretory cells: 2.7;Differentiating spermatogonia: 2.3;Endometrial secretory cells: 4.2;Monocyte progenitors: 4.9;Myosatellite cells: 2.3;Neutrophil progenitors: 4.9;Oocytes: 18.4;Schwann cells: 2.2;Undifferentiated spermatogonia: 4.5" "Cell type enhanced" "Detected in single" "amygdala excitatory: 1.8" "Group enriched" "Detected in many" 4 "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 4.4;Testicular Germ Cell Tumor (TCGA): 15.8" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 10 "classical monocyte: 7.1;intermediate monocyte: 2.4;myeloid DC: 2.0;non-classical monocyte: 6.0" "Group enriched" "Detected in many" 10 "dendritic cells: 2.0;monocytes: 7.1" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Prostate - Fibroblasts, Skin - Sebaceous gland cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA036236 Enhanced Approved Vesicles,Cytosol NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 9: Skin - Hair follicle development" "Cluster 51: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 4 "Vesicles, Cytosol" "HPA036236: " "unprognostic (6.73e-2)" "unprognostic (1.77e-1)" "unprognostic (6.27e-2)" "unprognostic (2.14e-1)" "unprognostic (8.10e-2)" "unprognostic (2.49e-2)" "unprognostic (1.39e-1)" "unprognostic (7.95e-2)" "unprognostic (5.08e-3)" "unprognostic (9.50e-2)" "unprognostic (3.48e-3)" ELOVL4 "CT118, SCA34, STGD2, STGD3" ENSG00000118402 "ELOVL fatty acid elongase 4" Q9GZR5 6 79914814-79947553 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Disease variant, FDA approved drug targets, Ichthyosis, Intellectual disability, Neurodegeneration, Spinocerebellar ataxia, Stargardt disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 98.1;retina: 163.6" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 63.3;Brain inhibitory neurons: 60.3;Cone photoreceptor cells: 161.5;Esophageal apical cells: 188.4;Esophageal suprabasal cells: 89.4;Other brain neurons: 64.3;Retinal amacrine cells: 53.5;Rod photoreceptor cells: 354.2;Suprabasal keratinocytes: 80.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "MAIT T-cell: 23.8" "Lineage enriched" "Detected in single" 238 "T-cells: 23.8" "Cancer enhanced" "Detected in many" "Rhabdoid: 18.8" "Colon - Colon enteroendocrine cells, Kidney - Podocytes, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 79: Photoreceptor cells - Phototransduction" 79 "unprognostic (2.29e-1)" "unprognostic (1.20e-1)" "unprognostic (1.24e-1)" "unprognostic (5.32e-2)" "unprognostic (5.06e-2)" "unprognostic (1.86e-1)" "unprognostic (7.39e-2)" "potential prognostic unfavorable (3.00e-5)" "unprognostic (3.83e-1)" "unprognostic (4.25e-1)" "unprognostic (9.85e-2)" "unprognostic (1.72e-1)" "unprognostic (1.85e-1)" "unprognostic (6.68e-3)" "unprognostic (1.18e-1)" "unprognostic (2.62e-1)" "unprognostic (5.44e-2)" "unprognostic (4.53e-2)" "unprognostic (1.31e-1)" "potential prognostic unfavorable (1.30e-5)" ELOVL5 "dJ483K16.1, HELO1, SCA38" ENSG00000012660 "ELOVL fatty acid elongase 5" Q9NYP7 6 53267398-53349179 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 707.4;Breast hormone-responsive cells: 563.4;Neutrophils: 1048.2;Prostatic glandular cells: 660.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Prostate - Prostate glandular cells, Skeletal muscle - Endothelial cells, Skin - Sebaceous gland cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017042, HPA047752, HPA054197" Enhanced Enhanced "Endoplasmic reticulum" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 25 "Endoplasmic reticulum" "CAB017042: , HPA047752: , HPA054197: " "unprognostic (1.15e-1)" "unprognostic (9.36e-2)" "unprognostic (2.91e-1)" "unprognostic (1.77e-2)" "unprognostic (1.21e-1)" "unprognostic (2.62e-1)" "unprognostic (3.48e-1)" "unprognostic (2.24e-3)" "unprognostic (3.52e-2)" "unprognostic (3.38e-3)" "unprognostic (6.39e-3)" "unprognostic (1.07e-1)" "potential prognostic unfavorable (1.04e-8)" "unprognostic (1.08e-1)" "unprognostic (1.36e-3)" "unprognostic (2.29e-1)" "unprognostic (2.04e-3)" "unprognostic (1.23e-1)" "unprognostic (1.29e-1)" "unprognostic (1.17e-1)" "unprognostic (8.91e-2)" "unprognostic (2.23e-1)" "unprognostic (2.95e-2)" "unprognostic (5.23e-2)" "unprognostic (3.68e-2)" "unprognostic (3.89e-3)" "unprognostic (9.93e-2)" "unprognostic (1.11e-1)" "unprognostic (1.11e-1)" "unprognostic (7.19e-3)" "unprognostic (1.35e-1)" ELOVL6 "FLJ23378, LCE, MGC5487" ENSG00000170522 "ELOVL fatty acid elongase 6" Q9H5J4 4 110045846-110199199 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 31.1" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 192.6;Esophageal apical cells: 188.2;Foveolar cells: 277.7;Megakaryocyte-Erythroid progenitors: 189.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 31.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "gdT-cell: 2.4;MAIT T-cell: 2.6;memory CD4 T-cell: 1.0;memory CD8 T-cell: 1.3;naive CD8 T-cell: 1.0;NK-cell: 3.3" "Group enriched" "Detected in many" 21 "NK-cells: 3.3;T-cells: 2.6" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary gland basal cells, Skeletal muscle - Endothelial cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042355 Uncertain NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 37: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 69: Urothelial cells - Basic cellular functions" 4 "HPA042355: " "unprognostic (2.05e-1)" "unprognostic (2.11e-2)" "unprognostic (2.14e-1)" "unprognostic (6.95e-2)" "potential prognostic favorable (3.94e-4)" "unprognostic (8.50e-2)" "unprognostic (3.63e-2)" "unprognostic (1.23e-1)" "unprognostic (2.02e-3)" "unprognostic (1.99e-3)" "unprognostic (1.07e-3)" "unprognostic (4.42e-1)" "unprognostic (5.06e-2)" "unprognostic (2.84e-1)" "unprognostic (1.04e-1)" "validated prognostic unfavorable (5.83e-4)" "validated prognostic unfavorable (5.47e-4)" "unprognostic (7.20e-2)" "unprognostic (3.10e-2)" "unprognostic (1.32e-1)" "unprognostic (3.47e-1)" "unprognostic (1.23e-1)" "unprognostic (7.52e-2)" "unprognostic (1.53e-2)" "unprognostic (1.42e-2)" "unprognostic (3.71e-3)" "unprognostic (2.35e-1)" "unprognostic (1.58e-1)" "unprognostic (1.48e-1)" "unprognostic (1.83e-2)" "unprognostic (6.94e-2)" ELOVL7 FLJ23563 ENSG00000164181 "ELOVL fatty acid elongase 7" A1L3X0 5 60751791-60844274 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 346.5;Distal convoluted tubule cells: 230.6;Endometrial luminal cells: 351.5;Epicardial cells: 286.5;Platelets: 466.5;Renal collecting duct intercalated cells: 230.8;Salivary basal cells: 185.4" "Cell type enriched" "Detected in all" 5 "endothelial cell: 1911.7" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 51.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 1.9;neutrophil: 1.3" "Lineage enriched" "Detected in single" 17 "granulocytes: 1.9" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells, Liver - Cholangiocytes, Prostate - Prostate glandular cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036337 Approved NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 47: Endothelial cells - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 104: Brain endothelial cells - Blood brain barrier" 11 "HPA036337: " "unprognostic (3.16e-2)" "unprognostic (6.80e-2)" "unprognostic (7.38e-2)" "unprognostic (2.00e-1)" "unprognostic (6.16e-2)" "unprognostic (2.31e-2)" "unprognostic (2.08e-1)" "unprognostic (2.34e-2)" "unprognostic (2.96e-1)" "unprognostic (1.11e-2)" "potential prognostic favorable (1.36e-9)" "unprognostic (4.08e-3)" "unprognostic (3.08e-2)" "unprognostic (1.15e-2)" "unprognostic (1.86e-2)" "unprognostic (1.63e-2)" "unprognostic (1.86e-2)" "unprognostic (2.15e-1)" "unprognostic (4.81e-2)" "unprognostic (5.75e-2)" "unprognostic (3.72e-1)" "unprognostic (1.25e-1)" "unprognostic (3.80e-2)" "unprognostic (1.79e-1)" "unprognostic (2.48e-2)" "unprognostic (1.46e-2)" "unprognostic (5.00e-1)" "unprognostic (5.61e-2)" "unprognostic (5.58e-2)" "unprognostic (1.74e-1)" "potential prognostic unfavorable (8.13e-4)" ELP1 "DYS, IKAP, IKBKAP, IKI3, TOT1" ENSG00000070061 "Elongator acetyltransferase complex subunit 1" O95163 9 108866898-108934328 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "tRNA processing" "Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adrenal cortex cells: 330.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 8 "basophil: 36.7" "Lineage enriched" "Detected in all" 8 "granulocytes: 36.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB021340, HPA049677, HPA050686" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 32: Basophils - Transcription" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 44: Non-specific - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 18: Adrenal cortex cells - Steroidogensis" 39 Cytosol Nucleoplasm "CAB021340: , HPA049677: , HPA050686: " "unprognostic (2.38e-3)" "potential prognostic unfavorable (9.67e-5)" "unprognostic (2.17e-1)" "unprognostic (2.02e-1)" "unprognostic (5.75e-2)" "unprognostic (7.13e-2)" "potential prognostic favorable (3.10e-4)" "unprognostic (2.59e-1)" "unprognostic (1.60e-1)" "potential prognostic favorable (3.38e-7)" "unprognostic (2.45e-3)" "unprognostic (1.67e-1)" "unprognostic (2.91e-2)" "unprognostic (5.56e-2)" "unprognostic (1.40e-1)" "unprognostic (9.21e-2)" "unprognostic (6.62e-2)" "unprognostic (2.66e-2)" "unprognostic (2.69e-1)" "unprognostic (1.13e-1)" "unprognostic (5.08e-2)" "unprognostic (1.13e-1)" "potential prognostic favorable (1.93e-4)" "unprognostic (1.48e-2)" "unprognostic (1.09e-1)" "unprognostic (2.19e-1)" "unprognostic (4.82e-2)" "unprognostic (1.03e-1)" "unprognostic (8.10e-2)" ELP2 "FLJ10879, STATIP1, StIP" ENSG00000134759 "Elongator acetyltransferase complex subunit 2" Q6IA86 18 36129444-36180557 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "tRNA processing" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002996, CAB020835" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 75: Ovary - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 13: Non-specific - Mixed function" "Cluster 7: Non-specific - Transcription" 10 Cytosol Nucleoplasm "CAB020835: , HPA002996: " "unprognostic (2.92e-2)" "unprognostic (4.82e-1)" "unprognostic (5.33e-1)" "unprognostic (7.46e-2)" "unprognostic (2.72e-2)" "unprognostic (3.43e-1)" "unprognostic (6.78e-2)" "potential prognostic favorable (7.59e-4)" "unprognostic (2.06e-1)" "unprognostic (3.33e-2)" "validated prognostic favorable (8.63e-6)" "validated prognostic favorable (3.26e-4)" "unprognostic (2.28e-2)" "unprognostic (6.05e-3)" "unprognostic (3.31e-1)" "unprognostic (2.38e-1)" "unprognostic (1.22e-1)" "unprognostic (7.06e-2)" "unprognostic (1.63e-3)" "unprognostic (9.30e-2)" "unprognostic (7.31e-2)" "unprognostic (9.60e-2)" "unprognostic (2.54e-1)" "unprognostic (7.60e-2)" "unprognostic (1.93e-1)" "unprognostic (5.41e-2)" "unprognostic (1.31e-1)" "unprognostic (1.99e-1)" "unprognostic (1.01e-1)" "unprognostic (3.88e-2)" "unprognostic (1.11e-1)" ELP3 "FLJ10422, KAT9" ENSG00000134014 "Elongator acetyltransferase complex subunit 3" Q9H9T3 8 28089673-28191156 "Disease related genes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" "Neurogenesis, tRNA processing" "Acyltransferase, RNA-binding, Transferase, tRNA-binding" "Amyotrophic lateral sclerosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 164.4;Endometrial luminal cells: 230.8;Renal collecting duct intercalated cells: 299.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025297, HPA025812" Uncertain Enhanced Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 13 Cytosol "HPA025297: , HPA025812: " "unprognostic (1.66e-1)" "unprognostic (3.50e-2)" "unprognostic (8.96e-2)" "unprognostic (1.43e-2)" "unprognostic (1.71e-3)" "unprognostic (3.11e-2)" "unprognostic (1.55e-1)" "unprognostic (1.30e-3)" "unprognostic (2.74e-1)" "unprognostic (3.09e-1)" "validated prognostic favorable (5.54e-6)" "validated prognostic favorable (9.17e-6)" "unprognostic (9.71e-2)" "unprognostic (4.72e-2)" "unprognostic (2.37e-1)" "unprognostic (2.68e-1)" "unprognostic (1.05e-1)" "unprognostic (4.21e-2)" "unprognostic (1.35e-1)" "unprognostic (3.00e-2)" "unprognostic (1.42e-2)" "unprognostic (4.42e-1)" "unprognostic (3.74e-2)" "unprognostic (2.37e-2)" "unprognostic (8.98e-2)" "unprognostic (3.54e-2)" "unprognostic (3.79e-2)" "unprognostic (3.52e-2)" "unprognostic (4.68e-1)" "unprognostic (1.75e-1)" "unprognostic (4.67e-2)" ELP4 "C11orf19, PAXNEB" ENSG00000109911 "Elongator acetyltransferase complex subunit 4" Q96EB1 11 31509755-31790324 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "tRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038572, HPA038573" Approved Supported Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 27: Cerebellum - Synaptic function" "Cluster 15: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 7: Non-specific - Transcription" 8 Nucleoplasm "HPA038572: , HPA038573: " "unprognostic (9.68e-3)" "unprognostic (6.62e-2)" "unprognostic (8.16e-2)" "unprognostic (1.76e-1)" "unprognostic (1.46e-1)" "unprognostic (3.13e-2)" "unprognostic (2.08e-1)" "unprognostic (1.88e-1)" "unprognostic (3.34e-3)" "unprognostic (8.02e-3)" "unprognostic (1.40e-3)" "unprognostic (8.30e-2)" "unprognostic (2.14e-1)" "potential prognostic unfavorable (1.78e-4)" "unprognostic (1.79e-3)" "potential prognostic unfavorable (1.72e-4)" "unprognostic (1.14e-1)" "potential prognostic favorable (7.01e-4)" "unprognostic (1.50e-1)" "unprognostic (9.70e-2)" "unprognostic (2.63e-2)" "unprognostic (2.71e-1)" "unprognostic (2.99e-2)" "unprognostic (6.60e-2)" "unprognostic (5.54e-2)" "unprognostic (3.17e-2)" "unprognostic (2.05e-2)" "unprognostic (2.24e-1)" "unprognostic (7.31e-2)" "unprognostic (4.54e-1)" "unprognostic (2.28e-1)" ELP5 "C17orf81, DERP6" ENSG00000170291 "Elongator acetyltransferase complex subunit 5" Q8TE02 17 7251416-7259940 "Essential proteins, Predicted intracellular proteins" "tRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 160.8" "Group enriched" "Detected in many" 9 "Early spermatids: 188.8;Late primary spermatocytes: 284.8;Late spermatids: 742.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023279, HPA052411" Uncertain Supported Nucleoplasm,Cytosol "Intracellular and membrane" Other NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 67: Testis - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 10 Nucleoplasm Cytosol "HPA023279: , HPA052411: " "unprognostic (2.50e-1)" "unprognostic (1.53e-1)" "potential prognostic favorable (6.46e-4)" "unprognostic (3.56e-1)" "unprognostic (5.82e-2)" "unprognostic (1.39e-1)" "unprognostic (3.58e-2)" "unprognostic (1.17e-1)" "unprognostic (3.24e-3)" "unprognostic (8.62e-2)" "unprognostic (6.88e-2)" "unprognostic (7.59e-3)" "unprognostic (5.35e-3)" "unprognostic (2.11e-2)" "unprognostic (2.78e-1)" "unprognostic (3.84e-1)" "unprognostic (7.41e-2)" "unprognostic (8.66e-2)" "unprognostic (4.28e-1)" "unprognostic (5.70e-2)" "unprognostic (3.42e-1)" "unprognostic (2.66e-1)" "unprognostic (3.33e-1)" "unprognostic (2.54e-1)" "unprognostic (1.86e-2)" "unprognostic (8.13e-2)" "unprognostic (1.93e-1)" "unprognostic (2.36e-3)" "unprognostic (1.88e-2)" ELP6 "C3orf75, FLJ20211, TMEM103" ENSG00000163832 "Elongator acetyltransferase complex subunit 6" Q0PNE2 3 47495640-47513712 "Essential proteins, Predicted intracellular proteins, Predicted membrane proteins" "tRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046358, HPA064545" Uncertain Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 8 "Nucleoplasm, Cytosol" Centrosome "HPA046358: , HPA064545: " "unprognostic (1.49e-1)" "unprognostic (2.25e-2)" "unprognostic (7.73e-2)" "unprognostic (4.02e-2)" "unprognostic (1.43e-1)" "unprognostic (3.51e-1)" "unprognostic (8.81e-3)" "unprognostic (2.91e-1)" "potential prognostic unfavorable (1.29e-5)" "unprognostic (3.80e-3)" "unprognostic (2.05e-2)" "potential prognostic favorable (1.05e-4)" "unprognostic (2.97e-3)" "unprognostic (8.23e-2)" "unprognostic (6.77e-3)" "unprognostic (2.35e-1)" "unprognostic (1.55e-1)" "unprognostic (2.96e-3)" "unprognostic (1.37e-1)" "unprognostic (2.83e-1)" "unprognostic (2.08e-1)" "unprognostic (2.80e-2)" "unprognostic (9.99e-2)" "unprognostic (1.74e-1)" "unprognostic (2.92e-3)" "unprognostic (7.47e-2)" "unprognostic (5.17e-2)" "unprognostic (1.61e-1)" "unprognostic (6.02e-3)" ELSPBP1 "E12, EDDM12, HE12" ENSG00000169393 "Epididymal sperm binding protein 1" Q96BH3 19 47994632-48025154 "Predicted intracellular proteins, Predicted secreted proteins" Fertilization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 39 "epididymis: 2669.4" "Cell type enriched" "Detected in some" 34 "Epididymal principal cells: 3233.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney Chromophobe (TCGA): 1.3;Skin Cutaneous Melanoma (TCGA): 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "Brain cancer: 3.3" "Not detected" "Not detected" "HPA044256, HPA050341" Enhanced "Secreted in male reproductive system" Other NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 38: Non-specific - Transcription" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" 51 "HPA044256: , HPA050341: " "unprognostic (4.62e-1)" "unprognostic (3.84e-1)" "unprognostic (3.84e-1)" EMB MGC71745 ENSG00000170571 Embigin Q6PCB8 5 50396192-50443248 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 161.1" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 260.8;Monocyte progenitors: 393.0;Neutrophil progenitors: 1921.4;Neutrophils: 837.4;NK-cells: 261.0;T-cells: 362.8" "Cell type enhanced" "Detected in many" "leukocyte: 546.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal cortex cells, Heart muscle - Macrophages, Skeletal muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 43: Hindbrain - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 6 "unprognostic (1.87e-1)" "unprognostic (1.28e-3)" "unprognostic (2.82e-2)" "unprognostic (1.84e-1)" "unprognostic (4.18e-2)" "unprognostic (7.23e-3)" "unprognostic (4.47e-2)" "unprognostic (1.73e-1)" "unprognostic (1.06e-2)" "unprognostic (1.87e-1)" "unprognostic (1.00e-1)" "unprognostic (7.02e-2)" "unprognostic (1.98e-2)" "unprognostic (1.06e-1)" "unprognostic (6.90e-2)" "unprognostic (9.12e-2)" "unprognostic (5.67e-2)" "unprognostic (1.07e-1)" "unprognostic (5.02e-3)" "unprognostic (1.45e-2)" "unprognostic (5.36e-3)" "unprognostic (1.53e-1)" "unprognostic (2.41e-2)" "unprognostic (1.75e-1)" "unprognostic (2.09e-2)" "unprognostic (1.01e-2)" "unprognostic (4.24e-1)" "potential prognostic unfavorable (8.84e-4)" "unprognostic (1.60e-1)" "unprognostic (2.11e-2)" "unprognostic (1.35e-1)" EMC1 KIAA0090 ENSG00000127463 "ER membrane protein complex subunit 1" Q8N766 1 19215660-19251552 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epicardial cells: 84.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048904 Approved NA NA 13000 "Cluster 33: Non-specific - ATP binding" "Cluster 42: Retina - Visual perception" "Cluster 14: Neurons - Synaptic function" "Cluster 37: Non-specific - mRNA processing" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 58 "HPA048904: " "unprognostic (1.65e-1)" "unprognostic (3.68e-2)" "unprognostic (8.60e-3)" "unprognostic (1.46e-2)" "unprognostic (3.86e-1)" "unprognostic (2.15e-1)" "unprognostic (8.51e-2)" "unprognostic (8.34e-2)" "unprognostic (2.00e-3)" "potential prognostic favorable (1.11e-4)" "unprognostic (9.96e-2)" "unprognostic (1.96e-1)" "potential prognostic unfavorable (1.42e-6)" "unprognostic (1.06e-2)" "unprognostic (3.30e-2)" "unprognostic (5.35e-2)" "unprognostic (3.63e-1)" "unprognostic (9.37e-2)" "unprognostic (3.59e-1)" "unprognostic (2.50e-2)" "unprognostic (1.94e-1)" "unprognostic (2.32e-1)" "unprognostic (6.24e-2)" "potential prognostic favorable (2.97e-5)" "unprognostic (3.58e-1)" "unprognostic (1.22e-1)" "unprognostic (2.51e-1)" "unprognostic (1.03e-1)" "unprognostic (1.27e-1)" EMC10 "C19orf63, HSM1, HSS1, INM02" ENSG00000161671 "ER membrane protein complex subunit 10" Q5UCC4 19 50476400-50490871 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" Angiogenesis "Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 173.6" "Cell type enriched" "Detected in many" 4 "Myonuclei: 3291.4" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 126.1;oligodendrocyte: 142.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053905, HPA062723" Approved "Secreted to blood" "Developmental protein" NA NA 1000000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 24: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 29 "HPA053905: , HPA062723: " "unprognostic (1.37e-1)" "unprognostic (6.59e-2)" "unprognostic (3.97e-2)" "unprognostic (8.49e-2)" "unprognostic (1.81e-1)" "unprognostic (8.41e-2)" "unprognostic (4.77e-2)" "unprognostic (8.51e-2)" "potential prognostic favorable (8.69e-4)" "unprognostic (8.78e-3)" "unprognostic (4.70e-2)" "potential prognostic favorable (1.85e-4)" "unprognostic (1.68e-1)" "unprognostic (1.17e-1)" "unprognostic (1.59e-1)" "unprognostic (2.89e-3)" "unprognostic (4.55e-1)" "unprognostic (1.99e-1)" "unprognostic (1.31e-1)" "potential prognostic favorable (3.52e-5)" "unprognostic (2.83e-1)" "unprognostic (2.24e-1)" "unprognostic (4.75e-1)" "unprognostic (1.69e-1)" "unprognostic (1.16e-1)" "unprognostic (3.89e-2)" "unprognostic (1.41e-1)" "unprognostic (5.62e-2)" "unprognostic (3.14e-2)" EMC2 "KIAA0103, TTC35" ENSG00000104412 "ER membrane protein complex subunit 2" Q15006 8 108443601-108489196 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 231.9;Late primary spermatocytes: 286.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022838 Approved NA NA 7100 "Cluster 29: Non-specific - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 61: BICR 18 - Protein kinases" "Cluster 110: Mural cells - ECM organization" 113 "HPA022838: " "unprognostic (3.96e-2)" "potential prognostic unfavorable (2.25e-5)" "unprognostic (8.60e-2)" "unprognostic (1.70e-1)" "unprognostic (9.09e-3)" "unprognostic (7.99e-2)" "unprognostic (1.40e-1)" "unprognostic (2.15e-1)" "unprognostic (6.52e-2)" "unprognostic (1.37e-1)" "unprognostic (6.00e-2)" "unprognostic (1.42e-2)" "unprognostic (6.24e-3)" "unprognostic (2.56e-2)" "unprognostic (1.13e-1)" "unprognostic (7.83e-2)" "unprognostic (1.00e-1)" "unprognostic (4.35e-2)" "unprognostic (2.33e-2)" "unprognostic (2.25e-1)" "unprognostic (2.35e-2)" "unprognostic (7.93e-2)" "unprognostic (1.28e-1)" "unprognostic (1.03e-1)" "unprognostic (1.63e-1)" "unprognostic (4.82e-2)" "unprognostic (4.99e-1)" "unprognostic (2.26e-1)" "unprognostic (3.50e-2)" EMC3 TMEM111 ENSG00000125037 "ER membrane protein complex subunit 3" Q9P0I2 3 9962682-10011202 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 360.6;Esophageal apical cells: 548.8;Late primary spermatocytes: 441.1;Platelets: 715.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042372 Approved NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 47: Platelets - Hemostasis" 47 "HPA042372: " "unprognostic (2.96e-1)" "unprognostic (2.01e-2)" "potential prognostic unfavorable (4.27e-4)" "unprognostic (8.39e-2)" "unprognostic (2.57e-1)" "unprognostic (1.23e-1)" "unprognostic (8.75e-2)" "unprognostic (6.28e-2)" "unprognostic (1.78e-2)" "potential prognostic favorable (3.25e-9)" "unprognostic (5.71e-2)" "unprognostic (6.60e-3)" "unprognostic (6.68e-2)" "unprognostic (3.99e-2)" "unprognostic (1.77e-1)" "unprognostic (3.36e-2)" "unprognostic (3.53e-1)" "unprognostic (9.91e-3)" "unprognostic (3.13e-2)" "unprognostic (1.23e-2)" "unprognostic (1.66e-1)" "unprognostic (1.23e-1)" "unprognostic (7.17e-2)" "unprognostic (8.78e-2)" "unprognostic (4.16e-3)" "unprognostic (1.85e-1)" "unprognostic (1.34e-1)" "unprognostic (3.26e-1)" "unprognostic (2.86e-1)" EMC4 "FLJ90746, MGC24415, PIG17, TMEM85" ENSG00000128463 "ER membrane protein complex subunit 4" Q5J8M3 15 34225013-34230156 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 543.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053440 Approved NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 85: Squamous epithelial cells - Keratinization" 79 "HPA053440: " "unprognostic (8.29e-2)" "unprognostic (8.96e-2)" "unprognostic (1.31e-1)" "unprognostic (1.24e-1)" "unprognostic (1.65e-2)" "unprognostic (2.36e-1)" "unprognostic (1.92e-1)" "potential prognostic unfavorable (4.96e-4)" "potential prognostic unfavorable (5.07e-4)" "unprognostic (2.99e-3)" "unprognostic (5.08e-2)" "unprognostic (2.95e-1)" "unprognostic (1.22e-1)" "potential prognostic unfavorable (2.25e-4)" "unprognostic (6.25e-2)" "unprognostic (6.85e-2)" "unprognostic (1.67e-1)" "unprognostic (8.76e-3)" "unprognostic (1.60e-1)" "unprognostic (3.14e-2)" "unprognostic (2.67e-2)" "unprognostic (2.36e-2)" "unprognostic (4.79e-2)" "unprognostic (1.56e-1)" "unprognostic (1.78e-1)" "unprognostic (4.14e-3)" "unprognostic (1.64e-1)" "unprognostic (1.29e-1)" "unprognostic (1.48e-1)" EMC6 "MGC2963, RAB5IFL, TMEM93" ENSG00000127774 "ER membrane protein complex subunit 6" Q9BV81 17 3668812-3669668 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 178.5" "Cell type enhanced" "Detected in all" "Early spermatids: 257.2;Esophageal apical cells: 271.7;Late primary spermatocytes: 238.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062681 Uncertain Approved Nucleoplasm,Centrosome NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 42: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 32 Centrosome Nucleoplasm "HPA062681: " "unprognostic (1.84e-2)" "unprognostic (9.40e-2)" "unprognostic (9.05e-2)" "unprognostic (1.99e-1)" "unprognostic (7.38e-2)" "unprognostic (4.24e-2)" "unprognostic (7.59e-2)" "unprognostic (5.55e-2)" "unprognostic (3.42e-2)" "unprognostic (9.65e-2)" "unprognostic (1.76e-1)" "unprognostic (1.22e-2)" "unprognostic (1.59e-2)" "potential prognostic unfavorable (1.44e-5)" "unprognostic (4.93e-1)" "unprognostic (2.98e-1)" "unprognostic (4.07e-1)" "unprognostic (3.81e-3)" "unprognostic (7.70e-2)" "unprognostic (1.62e-2)" "unprognostic (2.05e-2)" "unprognostic (4.23e-2)" "unprognostic (1.89e-1)" "unprognostic (1.84e-1)" "unprognostic (1.30e-1)" "unprognostic (1.39e-1)" "unprognostic (1.69e-1)" "unprognostic (2.04e-1)" "unprognostic (3.02e-1)" EMC7 "C11orf3, C15orf24" ENSG00000134153 "ER membrane protein complex subunit 7" Q9NPA0 15 34084017-34101862 "Essential proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 324.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010029 Approved NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 8: Non-specific - Secretory pathway" 67 "HPA010029: " "unprognostic (1.40e-1)" "unprognostic (1.36e-1)" "unprognostic (7.31e-3)" "unprognostic (2.01e-1)" "unprognostic (1.10e-2)" "unprognostic (3.27e-1)" "unprognostic (3.67e-2)" "potential prognostic unfavorable (1.85e-4)" "unprognostic (1.28e-3)" "potential prognostic favorable (6.80e-4)" "unprognostic (1.01e-1)" "unprognostic (4.78e-2)" "unprognostic (2.61e-1)" "unprognostic (1.20e-2)" "unprognostic (1.86e-1)" "unprognostic (2.33e-1)" "unprognostic (1.34e-1)" "unprognostic (1.45e-2)" "unprognostic (8.81e-2)" "unprognostic (1.01e-1)" "unprognostic (5.92e-3)" "unprognostic (2.52e-1)" "unprognostic (2.72e-1)" "unprognostic (1.01e-1)" "unprognostic (2.24e-1)" "unprognostic (2.93e-1)" "unprognostic (1.18e-1)" "unprognostic (1.01e-2)" "unprognostic (2.42e-1)" EMC8 "C16orf2, C16orf4, COX4NB, FAM158B, NOC4" ENSG00000131148 "ER membrane protein complex subunit 8" O43402 16 85771758-85799608 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 248.1;Late primary spermatocytes: 187.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049476 Approved Supported "Endoplasmic reticulum,Golgi apparatus" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 90 "Endoplasmic reticulum" "Golgi apparatus" "HPA049476: " "unprognostic (7.46e-3)" "unprognostic (5.96e-3)" "unprognostic (8.71e-2)" "unprognostic (1.56e-1)" "unprognostic (4.07e-2)" "unprognostic (2.72e-2)" "unprognostic (1.64e-2)" "potential prognostic unfavorable (7.76e-4)" "potential prognostic favorable (3.69e-4)" "unprognostic (2.43e-3)" "unprognostic (2.87e-3)" "unprognostic (7.52e-3)" "potential prognostic unfavorable (3.05e-7)" "unprognostic (2.25e-3)" "unprognostic (1.40e-2)" "unprognostic (1.14e-1)" "unprognostic (1.53e-1)" "unprognostic (6.77e-2)" "unprognostic (2.13e-1)" "unprognostic (1.36e-1)" "unprognostic (4.34e-2)" "unprognostic (2.75e-2)" "unprognostic (3.21e-1)" "unprognostic (1.04e-1)" "unprognostic (1.28e-1)" "unprognostic (6.10e-2)" "unprognostic (1.61e-1)" "unprognostic (8.79e-3)" "unprognostic (5.52e-2)" EMC9 "C14orf122, CGI-112, FAM158A" ENSG00000100908 "ER membrane protein complex subunit 9" Q9Y3B6 14 24138959-24141591 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 61.9;Enterocytes: 51.0;Late primary spermatocytes: 74.7;Late spermatids: 212.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078254 Approved NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 145 "HPA078254: " "unprognostic (3.04e-1)" "unprognostic (4.44e-2)" "unprognostic (1.43e-2)" "unprognostic (1.90e-1)" "unprognostic (5.90e-3)" "unprognostic (1.03e-1)" "unprognostic (1.16e-3)" "unprognostic (9.31e-2)" "unprognostic (1.38e-1)" "unprognostic (1.02e-3)" "unprognostic (2.04e-2)" "unprognostic (3.87e-3)" "unprognostic (5.88e-2)" "unprognostic (1.51e-3)" "unprognostic (5.55e-3)" "unprognostic (2.57e-2)" "unprognostic (1.75e-1)" "unprognostic (2.22e-2)" "unprognostic (2.15e-3)" "unprognostic (1.16e-2)" "unprognostic (2.06e-2)" "unprognostic (8.04e-2)" "unprognostic (2.76e-2)" "unprognostic (2.44e-2)" "unprognostic (4.36e-2)" "unprognostic (3.95e-1)" "unprognostic (1.29e-1)" "unprognostic (4.78e-2)" "unprognostic (2.07e-1)" EMCN MUC14 ENSG00000164035 Endomucin Q9ULC0 4 100395341-100880126 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hematopoietic stem cells: 128.6;Lymphatic endothelial cells: 251.1;Oocytes: 244.1;Tuft cells: 172.9;Vascular endothelial cells: 971.0" "Cell type enriched" "Detected in many" 9 "endothelial cell: 806.0" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 46.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Liver - Vascular endothelial cells, Prostate - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005928 Approved "Intracellular and membrane" "No annotated function" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" "HPA005928: " "unprognostic (2.18e-2)" "unprognostic (1.78e-1)" "unprognostic (2.89e-1)" "unprognostic (3.79e-2)" "unprognostic (3.18e-2)" "unprognostic (1.22e-1)" "unprognostic (1.29e-1)" "unprognostic (9.44e-3)" "unprognostic (1.51e-3)" "unprognostic (2.65e-2)" "validated prognostic favorable (3.76e-13)" "validated prognostic favorable (2.19e-5)" "unprognostic (3.95e-2)" "validated prognostic favorable (1.34e-4)" "validated prognostic favorable (1.27e-4)" "unprognostic (8.59e-3)" "unprognostic (9.98e-2)" "potential prognostic unfavorable (9.88e-4)" "unprognostic (1.50e-1)" "unprognostic (2.16e-1)" "unprognostic (6.04e-2)" "unprognostic (4.84e-2)" "unprognostic (1.09e-1)" "unprognostic (2.26e-2)" "unprognostic (3.11e-2)" "unprognostic (8.77e-2)" "unprognostic (3.06e-3)" "unprognostic (1.91e-3)" "unprognostic (2.36e-1)" "unprognostic (1.51e-1)" "unprognostic (2.09e-1)" EMD "LEMD5, STA" ENSG00000102119 Emerin P50402 X 154379273-154381574 "Disease related genes, Human disease related genes, Predicted membrane proteins" Actin-binding "Cardiomyopathy, Disease variant, Emery-Dreifuss muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Megakaryocytes: 272.0;Platelets: 198.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000609, CAB001545, CAB002029, CAB058694, CAB062552" Supported Enhanced "Nuclear membrane,Endoplasmic reticulum" NA NA 86000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 24: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 36: Non-specific - mRNA processing" "Cluster 103: Non-specific - Basic cellular processes" 194 "Nuclear membrane" "Endoplasmic reticulum" "CAB001545: , CAB002029: , CAB058694: , CAB062552: , HPA000609: " "unprognostic (1.81e-1)" "unprognostic (1.27e-1)" "unprognostic (3.35e-1)" "unprognostic (1.19e-1)" "unprognostic (5.22e-2)" "unprognostic (6.23e-2)" "unprognostic (8.07e-2)" "unprognostic (2.43e-2)" "unprognostic (6.00e-3)" "unprognostic (1.56e-2)" "unprognostic (1.95e-1)" "unprognostic (1.78e-1)" "unprognostic (8.68e-2)" "unprognostic (1.67e-1)" "potential prognostic unfavorable (5.26e-4)" "unprognostic (1.14e-1)" "unprognostic (6.50e-2)" "unprognostic (4.92e-2)" "unprognostic (6.76e-2)" "unprognostic (1.78e-1)" "unprognostic (5.11e-3)" "unprognostic (6.17e-2)" "unprognostic (2.01e-2)" "potential prognostic unfavorable (6.06e-4)" "unprognostic (9.57e-2)" "unprognostic (4.10e-2)" "unprognostic (2.52e-2)" "unprognostic (9.38e-2)" "unprognostic (3.45e-2)" "unprognostic (1.65e-2)" "unprognostic (1.14e-1)" EME1 "FLJ31364, MMS4L, SLX2A" ENSG00000154920 "Essential meiotic structure-specific endonuclease 1" Q96AY2 17 50373220-50381483 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.1;epididymis: 6.0;testis: 5.5" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 17.0;Early primary spermatocytes: 16.0;Epicardial cells: 31.8;Epididymal principal cells: 63.9;Megakaryocyte progenitors: 11.2;Megakaryocytes: 12.4;Oocytes: 9.2" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 34 "basophil: 18.7" "Lineage enriched" "Detected in single" 34 "granulocytes: 18.7" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Kidney - Fibroblasts, Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "CAB016127, HPA021202, HPA023854" Supported Approved Nucleoplasm NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 27: Breast cancer - Unknown function" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" 9 Nucleoplasm "CAB016127: , HPA021202: , HPA023854: " "unprognostic (1.88e-2)" "unprognostic (1.18e-1)" "unprognostic (2.79e-1)" "unprognostic (1.81e-1)" "unprognostic (6.84e-2)" "unprognostic (1.82e-1)" "unprognostic (2.38e-1)" "unprognostic (1.66e-3)" "unprognostic (3.46e-2)" "potential prognostic unfavorable (3.16e-6)" "validated prognostic unfavorable (1.91e-4)" "validated prognostic unfavorable (3.24e-6)" "unprognostic (1.26e-3)" "potential prognostic unfavorable (3.88e-6)" "unprognostic (1.60e-2)" "unprognostic (1.81e-3)" "unprognostic (7.37e-2)" "unprognostic (7.65e-2)" "potential prognostic unfavorable (1.18e-4)" "unprognostic (1.55e-1)" "unprognostic (3.45e-2)" "unprognostic (5.03e-3)" "unprognostic (5.27e-2)" "unprognostic (1.99e-1)" "unprognostic (1.66e-1)" "unprognostic (2.50e-1)" EME2 "FLJ00151, SLX2B" ENSG00000197774 "Essential meiotic structure-specific endonuclease subunit 2" A4GXA9 16 1772810-1781708 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Cardiomyocytes: 810.7;Epicardial cells: 366.1" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in some" 7 "Prostate Adenocarcinoma (TCGA): 7.9;Uterine Corpus Endometrial Carcinoma (TCGA): 6.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045770 Uncertain NA NA "Cluster 64: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 1 "HPA045770: " "unprognostic (3.68e-2)" "potential prognostic favorable (4.07e-5)" "unprognostic (9.60e-3)" "unprognostic (5.53e-3)" "unprognostic (4.95e-2)" "unprognostic (2.20e-3)" "unprognostic (2.05e-2)" "unprognostic (2.21e-2)" "unprognostic (2.49e-1)" "unprognostic (2.85e-2)" "unprognostic (4.27e-1)" EMG1 "C2F, Grcc2f, NEP1" ENSG00000126749 "EMG1 N1-specific pseudouridine methyltransferase" Q92979 12 6970913-6979936 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Methyltransferase, RNA-binding, rRNA-binding, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 54.8;Extravillous trophoblasts: 68.2;Migrating cytotrophoblasts: 73.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039304, HPA039666" Supported Supported "Nucleoplasm,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 22 "Nucleoli rim" "Nucleoplasm, Mitotic chromosome" "HPA039304: , HPA039666: " "unprognostic (3.38e-3)" "unprognostic (2.47e-1)" "potential prognostic favorable (6.45e-4)" "unprognostic (7.50e-2)" "unprognostic (1.14e-1)" "unprognostic (2.68e-1)" "unprognostic (2.15e-1)" "unprognostic (1.34e-1)" "unprognostic (9.72e-3)" "unprognostic (2.73e-2)" "unprognostic (5.12e-2)" "unprognostic (1.07e-1)" "unprognostic (5.52e-2)" "validated prognostic unfavorable (2.15e-4)" "validated prognostic unfavorable (3.18e-5)" "unprognostic (1.26e-2)" "unprognostic (1.23e-2)" "unprognostic (5.63e-2)" "unprognostic (2.30e-1)" "unprognostic (6.72e-2)" "unprognostic (1.37e-1)" "unprognostic (1.04e-1)" "unprognostic (7.97e-3)" "unprognostic (3.38e-2)" "unprognostic (1.35e-2)" "potential prognostic favorable (6.19e-4)" "unprognostic (1.69e-1)" "unprognostic (1.13e-1)" "unprognostic (2.00e-1)" "unprognostic (1.29e-1)" "unprognostic (1.41e-1)" EMID1 "EMI5, EMU1, hEmu1" ENSG00000186998 "EMI domain containing 1" Q96A84 22 29205896-29259597 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.5;lymphoid tissue: 53.2" "Cell type enhanced" "Detected in many" "Astrocytes: 107.6;Bergmann glia: 73.8;Erythrocyte progenitors: 73.4;Hematopoietic stem cells: 86.4;Mast cells: 46.9;Megakaryocyte progenitors: 68.2;Megakaryocyte-Erythroid progenitors: 165.0;Myosatellite cells: 47.8;Oligodendrocyte progenitor cells: 104.5;Thymocytes: 57.6" "Cell type enhanced" "Detected in many" "astrocyte: 79.4;Bergmann glia: 81.6;oligodendrocyte precursor cell: 100.5" "Cancer enhanced" "Detected in all" "Uterine Corpus Endometrial Carcinoma (TCGA): 108.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Leukemia: 31.5" "Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000592 Uncertain "Secreted in other tissues" "No annotated function" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" "HPA000592: " "unprognostic (1.36e-2)" "unprognostic (4.12e-2)" "unprognostic (2.39e-1)" "unprognostic (1.29e-1)" "unprognostic (2.92e-3)" "unprognostic (1.44e-2)" "unprognostic (2.00e-2)" "unprognostic (1.77e-2)" "unprognostic (2.45e-1)" "unprognostic (3.93e-2)" "unprognostic (3.66e-3)" "unprognostic (2.18e-2)" "unprognostic (1.86e-1)" "unprognostic (4.08e-1)" "unprognostic (7.60e-2)" "unprognostic (6.94e-3)" "unprognostic (1.11e-1)" "unprognostic (1.65e-1)" "unprognostic (3.15e-2)" "unprognostic (2.04e-1)" "unprognostic (6.15e-2)" "unprognostic (1.82e-3)" "unprognostic (1.08e-1)" "unprognostic (1.34e-1)" "unprognostic (3.44e-2)" "unprognostic (5.40e-2)" "unprognostic (1.98e-2)" "unprognostic (3.64e-2)" "unprognostic (4.92e-1)" "unprognostic (5.40e-2)" "unprognostic (6.61e-2)" EMILIN1 "DKFZp586M121, EMILIN, gp115" ENSG00000138080 "Elastin microfibril interfacer 1" Q9Y6C2 2 27078615-27086403 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 98.0;Endometrial stromal cells: 57.4;Fibroblasts: 91.8;Hepatic stellate cells: 180.7;Leydig cells: 104.8;Ovarian stromal cells: 78.3;Pericytes: 53.7;Peritubular myoid cells: 191.3;Pituicytes/FSCs: 39.2;Smooth muscle cells: 135.7;Vascular smooth muscle cells: 50.1" "Cell type enhanced" "Detected in some" "fibroblast: 33.1;pericyte: 30.2;vascular associated smooth muscle cell: 37.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 114.3" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Adrenal gland - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA002822 Supported "Secreted to extracellular matrix" "Cell adhesion" NA NA 4700000 "Cluster 13: Non-specific - Mitochondria" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 22 "HPA002822: " "potential prognostic favorable (2.82e-4)" "unprognostic (2.54e-1)" "unprognostic (2.39e-1)" "unprognostic (1.25e-2)" "unprognostic (3.96e-2)" "unprognostic (2.87e-2)" "unprognostic (3.85e-3)" "unprognostic (4.83e-2)" "unprognostic (5.66e-2)" "unprognostic (8.15e-2)" "potential prognostic unfavorable (4.15e-4)" "unprognostic (2.40e-2)" "potential prognostic unfavorable (4.15e-4)" "unprognostic (1.70e-1)" "unprognostic (1.24e-2)" "unprognostic (6.49e-2)" "unprognostic (4.59e-2)" "unprognostic (3.90e-2)" "unprognostic (3.07e-1)" "unprognostic (3.73e-2)" "unprognostic (6.25e-2)" "unprognostic (3.01e-1)" "unprognostic (1.11e-1)" "unprognostic (8.14e-2)" "unprognostic (2.58e-1)" "unprognostic (1.70e-2)" "unprognostic (1.28e-3)" "unprognostic (2.80e-2)" "unprognostic (3.42e-2)" "unprognostic (2.11e-2)" "unprognostic (1.85e-1)" EMILIN2 "FLJ33200, FOAP-10" ENSG00000132205 "Elastin microfibril interfacer 2" Q9BXX0 18 2847006-2916003 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 71.6" "Cell type enhanced" "Detected in many" "cDC: 295.1;Decidual stromal cells: 159.5;Endometrial luminal cells: 241.5;Endometrial stromal cells: 172.0;Hofbauer cells: 125.1;Macrophages: 221.8;Mast cells: 220.2;Monocyte progenitors: 262.9;monocytes: 571.1;Neutrophils: 204.9" "Group enriched" "Detected in many" 4 "leukocyte: 50.7;oligodendrocyte: 30.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 5.5" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "testis cancer: 23.6" "Adipose subcutaneous - Macrophages, Adrenal gland - Macrophages, Colon - Macrophages, Lung - Macrophages, Minor Salivary Gland - Macrophages, Skeletal muscle - Macrophages, Skin - Fibroblasts_2, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "spinal cord: 33.7" HPA064576 Supported "Secreted to extracellular matrix" "Cell adhesion" NA NA 1100000 "Cluster 41: Basophils - Unknown function" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 30: White matter - Myelination" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 2 "HPA064576: " "unprognostic (5.97e-2)" "unprognostic (3.05e-1)" "unprognostic (6.24e-3)" "unprognostic (1.72e-1)" "unprognostic (2.32e-1)" "unprognostic (1.20e-1)" "unprognostic (4.28e-2)" "unprognostic (3.87e-2)" "unprognostic (1.58e-2)" "unprognostic (9.62e-2)" "unprognostic (2.15e-2)" "unprognostic (3.63e-1)" "unprognostic (3.96e-2)" "unprognostic (2.60e-1)" "unprognostic (2.76e-2)" "unprognostic (9.28e-3)" "unprognostic (1.23e-1)" "unprognostic (3.47e-1)" "unprognostic (1.97e-1)" "unprognostic (2.00e-1)" "unprognostic (2.05e-1)" "unprognostic (6.07e-2)" "unprognostic (2.96e-1)" "unprognostic (8.62e-3)" "unprognostic (2.52e-2)" "unprognostic (1.79e-1)" "unprognostic (3.83e-2)" "unprognostic (2.08e-2)" "unprognostic (1.36e-1)" "unprognostic (1.88e-2)" EMILIN3 "C20orf130, dJ620E11.4, EMILIN5" ENSG00000183798 "Elastin microfibril interfacer 3" Q9NT22 20 41359962-41366818 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "epididymis: 50.6" "Group enriched" "Detected in some" 4 "Adipocytes: 16.2;Cardiomyocytes: 31.5;Endometrial stromal cells: 17.3;Epicardial cells: 56.9;Epididymal efferent duct absorptive cells: 44.1;Epididymal principal cells: 48.9;Oligodendrocyte progenitor cells: 20.0" "Group enriched" "Detected in some" 30 "fibroblast: 41.5;oligodendrocyte precursor cell: 28.4" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 21.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 3.4" "Adipose subcutaneous - Smooth muscle cells, Colon - Enteric glia cells, Kidney - Macrophages, Skin - Sebaceous gland cells, Stomach - Fibroblasts" "Region enriched" "Detected in single" 30 "cerebellum: 3.3" "Region enriched" "Detected in some" 4 "spinal cord: 5.4" "HPA044034, HPA059912, HPA078559" Enhanced Approved "Golgi apparatus" "Secreted to extracellular matrix" "No annotated function" NA NA 620000 "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 45: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 7 "Golgi apparatus" "HPA044034: , HPA059912: , HPA078559: " "unprognostic (1.90e-2)" "unprognostic (4.23e-3)" "unprognostic (2.68e-1)" "unprognostic (2.20e-2)" "unprognostic (1.16e-1)" "potential prognostic favorable (9.92e-4)" "unprognostic (1.42e-3)" "unprognostic (1.61e-1)" "unprognostic (5.44e-3)" "unprognostic (1.74e-1)" "unprognostic (3.42e-1)" "unprognostic (1.58e-1)" EML1 "ELP79, EMAP, EMAPL, HuEMAP" ENSG00000066629 "EMAP like 1" O00423 14 99737693-99942060 "Disease related genes, Predicted intracellular proteins" "Disease variant, Epilepsy, Intellectual disability, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 140.9;Choroid plexus epithelial cells: 126.1;Cone photoreceptor cells: 430.6;Microglia: 144.2;Retinal ganglion cells: 146.8;Rod photoreceptor cells: 437.1;Vascular endothelial cells: 131.0" "Cell type enhanced" "Detected in all" "medium spiny neuron: 311.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Prostate - Smooth muscle cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033137, HPA049105" Uncertain NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 13 "CAB033137: , HPA049105: " "unprognostic (1.21e-1)" "unprognostic (1.72e-2)" "unprognostic (2.00e-1)" "unprognostic (3.34e-1)" "unprognostic (5.38e-1)" "unprognostic (1.37e-2)" "unprognostic (1.10e-1)" "unprognostic (1.91e-1)" "unprognostic (6.46e-2)" "unprognostic (6.92e-3)" "potential prognostic favorable (1.57e-8)" "unprognostic (2.94e-3)" "unprognostic (9.26e-2)" "unprognostic (6.19e-2)" "unprognostic (1.20e-2)" "unprognostic (1.02e-1)" "unprognostic (1.80e-2)" "unprognostic (2.51e-2)" "unprognostic (5.96e-3)" "unprognostic (4.18e-2)" "unprognostic (1.81e-1)" "unprognostic (8.94e-3)" "unprognostic (9.08e-2)" "unprognostic (9.37e-2)" "unprognostic (2.74e-2)" "unprognostic (6.95e-2)" "unprognostic (7.46e-2)" "unprognostic (1.29e-2)" "unprognostic (6.67e-2)" "unprognostic (1.41e-2)" "unprognostic (5.56e-2)" EML2 "ELP70, EMAP-2, EMAP2" ENSG00000125746 "EMAP like 2" O95834 19 45606994-45645602 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Rod photoreceptor cells: 265.6;Syncytiotrophoblasts: 183.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skin - Keratinocyte (other), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012757 Approved NA NA 1200000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 73: Brain - Neuronal signaling" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 79: Photoreceptor cells - Phototransduction" 5 "HPA012757: " "unprognostic (5.86e-2)" "unprognostic (7.58e-2)" "unprognostic (1.58e-2)" "unprognostic (2.04e-1)" "unprognostic (1.45e-1)" "unprognostic (1.36e-1)" "unprognostic (1.25e-1)" "unprognostic (2.78e-2)" "unprognostic (6.74e-2)" "unprognostic (3.52e-1)" "potential prognostic favorable (5.52e-4)" "unprognostic (7.53e-2)" "unprognostic (4.28e-1)" "unprognostic (2.87e-2)" "unprognostic (2.08e-1)" "unprognostic (1.22e-2)" "unprognostic (5.39e-2)" "unprognostic (1.72e-1)" "unprognostic (3.08e-1)" "potential prognostic unfavorable (9.02e-4)" "unprognostic (1.95e-1)" "unprognostic (9.88e-2)" "unprognostic (3.63e-1)" "unprognostic (8.00e-3)" "unprognostic (2.09e-1)" "unprognostic (5.24e-2)" "unprognostic (1.95e-1)" "unprognostic (1.73e-2)" "unprognostic (1.42e-1)" "unprognostic (7.43e-2)" "unprognostic (1.50e-1)" EML3 "ELP95, FLJ35827" ENSG00000149499 "EMAP like 3" Q32P44 11 62602218-62612775 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 7 "Esophageal apical cells: 767.1;Esophageal suprabasal cells: 212.9" "Cell type enhanced" "Detected in many" "astrocyte: 29.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells, Pituitary gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 24: Non-specific - Unknown function" "Cluster 85: Squamous epithelial cells - Keratinization" 32 "unprognostic (6.39e-2)" "unprognostic (3.47e-2)" "unprognostic (6.26e-3)" "unprognostic (3.33e-2)" "unprognostic (5.43e-2)" "unprognostic (7.21e-2)" "unprognostic (3.15e-1)" "unprognostic (4.50e-3)" "unprognostic (2.01e-1)" "unprognostic (1.58e-1)" "unprognostic (1.32e-2)" "unprognostic (1.98e-2)" "unprognostic (7.87e-2)" "unprognostic (3.45e-2)" "unprognostic (2.69e-2)" "unprognostic (4.80e-2)" "unprognostic (3.56e-2)" "unprognostic (1.91e-1)" "unprognostic (8.30e-2)" "unprognostic (2.98e-2)" "unprognostic (2.13e-2)" "unprognostic (7.37e-3)" "unprognostic (1.06e-1)" "unprognostic (3.38e-1)" "unprognostic (4.90e-2)" "unprognostic (2.13e-3)" "unprognostic (2.31e-1)" "unprognostic (3.51e-1)" "unprognostic (5.07e-2)" "unprognostic (2.16e-1)" "unprognostic (8.50e-2)" EML4 "C2orf2, ELP120, ROPP120" ENSG00000143924 "EMAP like 4" Q9HC35 2 42169353-42332548 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Innate lymphoid cells: 1052.7;Neutrophil progenitors: 731.7;Neutrophils: 800.0;Pituicytes/FSCs: 672.7;T-cells: 898.7;Urothelial cells: 685.3" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 543.8;leukocyte: 709.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Rhabdoid: 174.7" "Skeletal muscle - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036687, HPA036688, HPA065337" Enhanced Supported "Microtubules,Cytokinetic bridge,Primary cilium,Cytosol,Perinuclear theca,Calyx,Principal piece,Annulus" Yes NA 25000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 12: Non-specific - Vasculature" "Cluster 5: Rhabdoid - Unknown function" "Cluster 9: T-cells - Adaptive immunity: Regulation" 29 "Microtubules, Primary cilium, Annulus" "Cytokinetic bridge, Cytosol, Perinuclear theca, Calyx, Principal piece" "HPA036687: , HPA036688: , HPA065337: " "unprognostic (1.51e-1)" "unprognostic (1.19e-1)" "unprognostic (7.71e-3)" "unprognostic (3.55e-2)" "unprognostic (2.15e-2)" "unprognostic (1.51e-1)" "unprognostic (1.55e-2)" "unprognostic (1.67e-2)" "unprognostic (4.26e-2)" "unprognostic (2.13e-3)" "potential prognostic favorable (1.20e-7)" "unprognostic (3.22e-2)" "unprognostic (4.54e-2)" "unprognostic (5.48e-2)" "unprognostic (9.11e-3)" "unprognostic (1.26e-1)" "unprognostic (2.47e-2)" "unprognostic (2.07e-1)" "unprognostic (2.31e-1)" "unprognostic (8.68e-3)" "unprognostic (3.29e-1)" "potential prognostic unfavorable (8.70e-4)" "unprognostic (2.68e-2)" "unprognostic (1.40e-1)" "unprognostic (7.47e-3)" "unprognostic (7.95e-2)" "unprognostic (1.09e-2)" "unprognostic (3.25e-1)" "unprognostic (2.81e-1)" "unprognostic (2.30e-2)" "unprognostic (9.38e-2)" EML5 "EMAP-2, FAP16, HuEMAP-2" ENSG00000165521 "EMAP like 5" Q05BV3 14 88612431-88792953 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "ovary: 10.4;retina: 8.4" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 872.2;Brain inhibitory neurons: 239.0;Cone photoreceptor cells: 335.4;Granulosa cells: 540.9;Lactotrophs: 245.5;Pancreatic islet cells: 250.5;Prostatic glandular cells: 383.1;Retinal amacrine cells: 255.0;Retinal ganglion cells: 575.6;Thyrotrophs: 367.8" "Cell type enhanced" "Detected in all" "cerebellar inhibitory: 1415.8" "Group enriched" "Detected in some" 8 "Prostate Adenocarcinoma (TCGA): 5.2;Uterine Corpus Endometrial Carcinoma (TCGA): 2.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 15 "Neuroblastoma: 35.2" "Adrenal gland - Adrenal cortex cells, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "olfactory bulb: 42.5" "HPA054019, HPA055379" Uncertain NA NA "Cluster 61: Non-specific - Transcription" "Cluster 35: Non-specific - DNA binding" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 1 "HPA054019: , HPA055379: " "unprognostic (1.49e-1)" "potential prognostic favorable (8.78e-4)" "unprognostic (1.81e-1)" "unprognostic (7.83e-2)" "unprognostic (1.54e-2)" "unprognostic (1.47e-1)" "unprognostic (4.15e-1)" EML6 FLJ42562 ENSG00000214595 "EMAP like 6" Q6ZMW3 2 54723499-54972025 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 8.9;retina: 11.3" "Cell type enhanced" "Detected in many" "Astrocytes: 193.3;Brain excitatory neurons: 283.8;Brain inhibitory neurons: 258.7;Ependymal cells: 371.0;Gonadotrophs: 187.4;Lactotrophs: 175.7;Other brain neurons: 219.0;Retinal bipolar cells: 171.7;Retinal horizontal cells: 246.4;Rod photoreceptor cells: 194.2;Somatotrophs: 183.8;Thyrotrophs: 192.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "lymphoma: 9.7;Neuroblastoma: 7.2" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062808, HPA068759" Uncertain Approved Vesicles,Mitochondria NA NA "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 53: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 109: Neurons - Neuronal signaling" Mitochondria Vesicles "HPA062808: , HPA068759: " "unprognostic (6.28e-3)" "unprognostic (1.11e-1)" "unprognostic (3.00e-2)" "unprognostic (2.84e-2)" "potential prognostic favorable (3.26e-5)" "unprognostic (6.32e-2)" "unprognostic (3.50e-1)" "unprognostic (3.66e-3)" "unprognostic (3.00e-2)" "unprognostic (3.75e-1)" "unprognostic (3.99e-2)" EMP1 "CL-20, TMP" ENSG00000134531 "Epithelial membrane protein 1" P54849 12 13196723-13219941 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 1936.4;vagina: 705.5" "Cell type enriched" "Detected in many" 7 "Esophageal apical cells: 30858.3" "Cell type enhanced" "Detected in many" "endothelial cell: 133.1;fibroblast: 80.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "myeloid DC: 3.5" "Lineage enriched" "Detected in single" 13 "dendritic cells: 3.5" "Cancer enhanced" "Detected in all" "Rhabdoid: 589.7" "Kidney - Endothelial cells, Spleen - Fibroblasts_2, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "midbrain: 5.9;spinal cord: 21.0" HPA046912 Approved Vesicles NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 39: Astrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 84: Apical squamous epithelium - Cornification" 55 Vesicles "HPA046912: " "unprognostic (1.54e-1)" "unprognostic (1.58e-2)" "unprognostic (2.79e-1)" "unprognostic (2.70e-1)" "unprognostic (2.16e-1)" "unprognostic (2.07e-1)" "unprognostic (2.42e-1)" "unprognostic (2.15e-3)" "unprognostic (2.18e-1)" "unprognostic (2.67e-1)" "unprognostic (1.23e-2)" "potential prognostic favorable (1.56e-4)" "unprognostic (2.03e-1)" "unprognostic (1.07e-2)" "unprognostic (1.25e-2)" "unprognostic (4.06e-2)" "potential prognostic unfavorable (4.90e-4)" "unprognostic (1.30e-1)" "unprognostic (1.13e-1)" "potential prognostic unfavorable (2.13e-5)" "unprognostic (9.60e-2)" "potential prognostic unfavorable (9.74e-5)" "unprognostic (3.46e-3)" "unprognostic (3.85e-1)" "unprognostic (9.94e-2)" "potential prognostic favorable (5.28e-4)" "unprognostic (3.97e-2)" "unprognostic (3.23e-2)" "unprognostic (5.16e-2)" "unprognostic (1.31e-1)" "unprognostic (3.25e-2)" EMP2 XMP ENSG00000213853 "Epithelial membrane protein 2" P54851 16 10528422-10580632 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 214.6" "Cell type enriched" "Detected in many" 4 "Alveolar cells type 1: 5548.1" "Cell type enhanced" "Detected in many" "endothelial cell: 251.9;pericyte: 119.1;vascular associated smooth muscle cell: 115.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Liver - Hepatocytes, Lung - Alveolar cells type 1, Skeletal muscle - Endothelial cells, Thyroid gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014711, HPA070816" Approved Approved Nucleoplasm,Cytosol No Yes "Cluster 58: Skin - Keratinization" "Cluster 19: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 81: Alveolar cells - Lung function" 1 Nucleoplasm Cytosol "HPA014711: , HPA070816: " "unprognostic (2.47e-2)" "unprognostic (3.55e-2)" "unprognostic (2.03e-1)" "unprognostic (3.35e-2)" "unprognostic (4.36e-2)" "unprognostic (8.06e-2)" "validated prognostic unfavorable (1.27e-4)" "validated prognostic unfavorable (3.33e-4)" "unprognostic (1.90e-1)" "unprognostic (4.55e-2)" "unprognostic (1.72e-1)" "unprognostic (8.32e-2)" "potential prognostic unfavorable (6.54e-4)" "unprognostic (6.44e-3)" "unprognostic (8.42e-3)" "unprognostic (2.44e-2)" "unprognostic (1.76e-1)" "unprognostic (5.66e-2)" "unprognostic (2.48e-1)" "unprognostic (7.60e-2)" "unprognostic (1.99e-1)" "unprognostic (4.05e-2)" "unprognostic (2.80e-1)" "unprognostic (2.17e-1)" "unprognostic (1.67e-1)" "unprognostic (6.10e-2)" "unprognostic (3.57e-1)" "unprognostic (3.07e-1)" "unprognostic (1.97e-1)" "unprognostic (1.44e-1)" "unprognostic (1.03e-1)" EMP3 YMP ENSG00000142227 "Epithelial membrane protein 3" P54852 19 48321509-48330553 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "cDC: 752.3;Decidual stromal cells: 698.7;Hofbauer cells: 551.4;Macrophages: 402.2;Mast cells: 672.5;Melanocytes: 1040.7;Monocyte progenitors: 368.2;monocytes: 816.5;Plasma cells: 382.9;Platelets: 891.0" "Cell type enhanced" "Detected in many" "leukocyte: 161.1;pericyte: 119.2" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 922.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062030 Approved "Vesicles,Plasma membrane" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 82: Dendritic cells - Antigen presentation" 45 "Vesicles, Plasma membrane" "HPA062030: " "unprognostic (4.29e-1)" "unprognostic (1.25e-3)" "unprognostic (8.17e-2)" "unprognostic (1.85e-2)" "unprognostic (1.07e-2)" "unprognostic (2.32e-1)" "unprognostic (2.58e-2)" "potential prognostic unfavorable (2.37e-6)" "unprognostic (3.26e-3)" "unprognostic (2.95e-1)" "unprognostic (1.64e-3)" "unprognostic (1.06e-2)" "unprognostic (3.75e-2)" "unprognostic (1.13e-2)" "unprognostic (2.11e-1)" "unprognostic (6.73e-2)" "unprognostic (1.09e-2)" "unprognostic (4.53e-2)" "unprognostic (1.24e-1)" "unprognostic (5.24e-2)" "unprognostic (9.34e-2)" "unprognostic (3.85e-2)" "unprognostic (2.76e-3)" "unprognostic (3.21e-1)" "unprognostic (2.04e-2)" "unprognostic (1.85e-2)" "unprognostic (4.11e-2)" "unprognostic (1.98e-3)" "unprognostic (1.15e-1)" "unprognostic (2.51e-1)" "unprognostic (2.24e-1)" EMSY C11orf30 ENSG00000158636 "EMSY transcriptional repressor, BRCA2 interacting" Q7Z589 11 76444923-76553031 "Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012234, HPA050777" Supported Supported Nucleoplasm,Centrosome NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 16: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 28 Nucleoplasm Centrosome "CAB012234: , HPA050777: " "unprognostic (1.19e-3)" "unprognostic (3.78e-2)" "unprognostic (9.15e-3)" "unprognostic (2.12e-2)" "unprognostic (2.28e-1)" "unprognostic (9.46e-2)" "unprognostic (2.82e-2)" "unprognostic (3.37e-2)" "potential prognostic unfavorable (1.55e-4)" "validated prognostic favorable (9.45e-4)" "validated prognostic favorable (2.09e-4)" "unprognostic (1.02e-1)" "unprognostic (2.89e-2)" "unprognostic (1.70e-2)" "unprognostic (1.41e-1)" "unprognostic (3.24e-1)" "unprognostic (3.06e-2)" "unprognostic (2.51e-1)" "unprognostic (1.30e-1)" "unprognostic (9.36e-3)" "unprognostic (2.47e-3)" "unprognostic (3.62e-2)" "potential prognostic favorable (5.60e-4)" "unprognostic (9.31e-2)" "unprognostic (2.79e-3)" "unprognostic (3.20e-1)" "unprognostic (1.61e-1)" "unprognostic (3.41e-2)" "unprognostic (1.94e-1)" EMX1 ENSG00000135638 "Empty spiracles homeobox 1" Q04741 2 72916260-72936071 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 16.4;kidney: 39.9" "Group enriched" "Detected in some" 4 "Distal convoluted tubule cells: 236.7;Oocytes: 119.7;Renal collecting duct principal cells: 103.8;Renal connecting tubule cells: 257.1" "Cell type enhanced" "Detected in some" "hippocampal CA4: 22.0;upper-layer intratelencephalic: 22.6" "Group enriched" "Detected in many" 6 "Kidney Chromophobe (TCGA): 23.6;Kidney Renal Clear Cell Carcinoma (TCGA): 8.6;Kidney Renal Papillary Cell Carcinoma (TCGA): 20.1" "Group enriched" "Detected in many" 10 "amygdala: 15.8;basal ganglia: 21.8;cerebral cortex: 58.5;hippocampal formation: 21.1;white matter: 31.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Kidney - Intercalated cells" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 14 "amygdala: 4.5;cerebral cortex: 14.5;hippocampal formation: 11.1" "HPA006230, HPA006421" Approved Supported "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 72: Kidney - Transmembrane transport" "Cluster 53: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 1 "Nucleoli, Nucleoli rim" "Mitotic chromosome" "HPA006230: , HPA006421: " "unprognostic (8.02e-2)" "unprognostic (1.66e-2)" "unprognostic (6.24e-2)" "unprognostic (1.80e-1)" "unprognostic (1.52e-2)" "unprognostic (1.12e-1)" "potential prognostic favorable (1.65e-4)" "unprognostic (3.04e-2)" "unprognostic (4.56e-3)" "unprognostic (2.80e-1)" "unprognostic (5.80e-2)" "unprognostic (7.08e-2)" "unprognostic (2.31e-1)" EMX2 ENSG00000170370 "Empty spiracles homeobox 2" Q04743 10 117542445-117549546 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 64.0;endometrium 1: 79.8;epididymis: 98.5" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 219.4;Endometrial stromal cells: 122.5;Epididymal basal cells: 169.4;Epididymal efferent duct absorptive cells: 477.4;Epididymal efferent duct ciliated cells: 179.6;Epididymal principal cells: 455.0;Fallopian secretory cells: 113.9;Granulosa cells: 459.0;Renal collecting duct principal cells: 128.7;Renal connecting tubule cells: 102.3;Smooth muscle cells: 113.0" "Cell type enhanced" "Detected in some" "astrocyte: 55.1;pericyte: 26.3;vascular associated smooth muscle cell: 32.3" "Group enriched" "Detected in many" 9 "Kidney Chromophobe (TCGA): 26.5;Kidney Renal Clear Cell Carcinoma (TCGA): 32.2;Kidney Renal Papillary Cell Carcinoma (TCGA): 62.1;Ovary Serous Cystadenocarcinoma (TCGA): 81.2;Uterine Corpus Endometrial Carcinoma (TCGA): 87.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Kidney cancer: 3.8;ovarian cancer: 13.2;Uterine cancer: 12.8" "Skin - Fibroblasts_2, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "amygdala: 17.5;basal ganglia: 18.8;cerebral cortex: 23.3;hippocampal formation: 30.0;white matter: 10.9" "HPA003497, HPA065294" Enhanced Supported Approved Nucleoplasm NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 2 Nucleoplasm "HPA003497: , HPA065294: " "unprognostic (1.88e-1)" "unprognostic (2.04e-1)" "potential prognostic favorable (1.53e-4)" "unprognostic (1.89e-1)" "unprognostic (1.18e-3)" "unprognostic (5.04e-2)" "validated prognostic favorable (1.92e-9)" "validated prognostic favorable (1.73e-5)" "potential prognostic favorable (5.00e-4)" "unprognostic (1.73e-1)" "unprognostic (6.65e-2)" "unprognostic (2.70e-1)" "potential prognostic favorable (1.63e-4)" EN1 ENSG00000163064 "Engrailed homeobox 1" Q05925 2 118842171-118847648 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" Dwarfism "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 5 "adipose tissue: 3.4;brain: 8.5;skeletal muscle: 13.0;skin 1: 10.0" "Cell type enhanced" "Detected in some" "Breast hormone-responsive cells: 3.0;Breast myoepithelial cells: 4.3;Breast secretory cells: 10.2;Epididymal clear cells: 6.1;Fibroblasts: 3.2;Myonuclei: 9.6;Myosatellite cells: 8.1;Other brain neurons: 3.1;Pericytes: 2.7;Smooth muscle cells: 36.4" "Cell type enhanced" "Detected in some" "Bergmann glia: 2.0;oligodendrocyte precursor cell: 3.5" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 9.2" "Region enriched" "Detected in many" 6 "midbrain: 42.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 6.7;breast cancer: 6.9" "Skin - Eccrine sweat gland cells" "Region enriched" "Detected in single" 5 "midbrain: 4.9" "Region enriched" "Detected in some" 6 "midbrain: 28.7" "CAB014884, HPA073141" Enhanced Approved "Nucleoplasm,Nucleoli rim" NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 27: Breast cancer - Unknown function" "Cluster 62: Smooth muscle cells - Muscle contraction" 7 "Nucleoli rim" Nucleoplasm "CAB014884: , HPA073141: " "unprognostic (3.46e-2)" "unprognostic (8.58e-2)" "unprognostic (1.03e-1)" "unprognostic (4.63e-2)" "potential prognostic unfavorable (3.01e-4)" "unprognostic (1.65e-2)" "unprognostic (3.02e-1)" "unprognostic (2.87e-1)" "unprognostic (2.86e-1)" "unprognostic (9.61e-2)" "unprognostic (8.85e-2)" "unprognostic (1.89e-1)" "potential prognostic unfavorable (2.99e-4)" EN2 ENSG00000164778 "Engrailed homeobox 2" P19622 7 155458129-155464831 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 41 "brain: 34.8" "Cell type enhanced" "Detected in some" "Bergmann glia: 6.8;Brain excitatory neurons: 12.2;Endometrial glandular cells: 10.3;Endometrial luminal cells: 7.4;Epididymal efferent duct absorptive cells: 23.7;Epididymal efferent duct ciliated cells: 10.1;Melanocytes: 5.6;Oocytes: 4.6" "Group enriched" "Detected in some" 4 "cerebellar inhibitory: 41.5;upper rhombic lip: 38.7" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 10.1" "Group enriched" "Detected in many" 6 "cerebellum: 38.7;midbrain: 16.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 12.7" "Testis - Spermatocytes" "Region enriched" "Detected in some" 8 "cerebellum: 27.8" "Region enriched" "Detected in many" 5 "cerebellum: 82.1" "HPA045646, HPA069809" Supported "Nucleoplasm,Nucleoli,Nucleoli fibrillar center" No No "Cluster 71: Cerebellum - Nervous system development" "Cluster 2: Neurons - Nucleosome" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 2: Cerebellar granular cells - Neuronal signaling" Nucleoplasm "Nucleoli, Nucleoli fibrillar center" "HPA045646: , HPA069809: " "unprognostic (3.55e-2)" "potential prognostic unfavorable (1.07e-5)" "unprognostic (1.05e-2)" "unprognostic (2.98e-1)" "potential prognostic unfavorable (1.18e-5)" "unprognostic (5.95e-3)" "unprognostic (2.13e-1)" "unprognostic (4.44e-2)" ENAH "FLJ10773, MENA, NDPP1" ENSG00000154380 "ENAH actin regulator" Q8N8S7 1 225486765-225653142 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Sertoli cells: 614.7;Smooth muscle cells: 693.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028448, HPA028696" Enhanced Enhanced "Plasma membrane,Focal adhesion sites,Cytosol" NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 19: Astrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 62: Smooth muscle cells - Muscle contraction" 31 "Plasma membrane, Focal adhesion sites, Cytosol" "HPA028448: , HPA028696: " "unprognostic (1.44e-1)" "unprognostic (2.64e-2)" "unprognostic (9.41e-2)" "unprognostic (2.23e-3)" "unprognostic (1.20e-1)" "unprognostic (2.44e-2)" "unprognostic (3.52e-3)" "potential prognostic favorable (2.55e-4)" "unprognostic (1.70e-1)" "potential prognostic unfavorable (6.45e-4)" "unprognostic (1.45e-2)" "unprognostic (1.18e-2)" "unprognostic (1.26e-2)" "unprognostic (4.99e-3)" "unprognostic (2.68e-2)" "unprognostic (2.80e-1)" "unprognostic (2.56e-2)" "unprognostic (1.06e-1)" "unprognostic (9.34e-3)" "unprognostic (2.38e-1)" "unprognostic (2.78e-3)" "unprognostic (5.45e-2)" "unprognostic (2.78e-1)" "unprognostic (1.02e-1)" "unprognostic (1.13e-2)" "unprognostic (2.27e-2)" "unprognostic (4.57e-2)" "unprognostic (1.57e-1)" "unprognostic (1.62e-1)" "unprognostic (2.49e-2)" "unprognostic (1.58e-1)" ENAM AIH2 ENSG00000132464 Enamelin Q9NRM1 4 70628744-70646824 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Biomineralization "Amelogenesis imperfecta, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 7.1;heart muscle: 6.1;kidney: 8.4;skeletal muscle: 4.5" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 9.6;Loop of henle epithelial cells: 7.9;Myonuclei: 2.9;pDCs: 3.9;Proximal tubule cells: 3.9;Renal collecting duct intercalated cells: 12.8;Renal collecting duct principal cells: 3.1;Renal connecting tubule cells: 9.9" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Kidney Chromophobe (TCGA): 9.2;Kidney Renal Clear Cell Carcinoma (TCGA): 2.6;Kidney Renal Papillary Cell Carcinoma (TCGA): 4.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 2.8;Rhabdoid: 1.1" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Cardiomyocytes, Pituitary gland - Corticotropes, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Secreted to extracellular matrix" Other NA NA 16000 "Cluster 72: Kidney - Transmembrane transport" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" "unprognostic (6.00e-2)" "validated prognostic favorable (3.02e-9)" "validated prognostic favorable (9.33e-4)" "unprognostic (1.34e-2)" "unprognostic (6.22e-2)" "unprognostic (1.86e-3)" "unprognostic (1.91e-2)" ENC1 "ENC-1, KLHL37, NRPB, PIG10, TP53I10" ENSG00000171617 "Ectodermal-neural cortex 1" O14682 5 74627406-74641424 "Cancer-related genes, Predicted intracellular proteins" "Actin-binding, Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "brain: 279.1" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 197.3;Gastric progenitor cells: 106.4;Granulosa cells: 131.4;Mucous neck cells: 141.4;Ocular epithelial cells: 99.5;Pancreatic duct cells: 147.0;Respiratory ionocytes: 94.0" "Cell type enhanced" "Detected in all" "hippocampal CA4: 479.3;upper-layer intratelencephalic: 516.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Pancreas - Ductal cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 688.5" HPA078061 Uncertain "Plasma membrane" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Neurons - Synaptic function & neurogenesis" 11 "Plasma membrane" "HPA078061: " "unprognostic (7.91e-2)" "potential prognostic unfavorable (6.04e-4)" "unprognostic (9.60e-2)" "unprognostic (3.92e-2)" "unprognostic (6.96e-2)" "unprognostic (3.87e-2)" "unprognostic (9.18e-2)" "unprognostic (4.87e-2)" "unprognostic (3.60e-3)" "unprognostic (1.97e-3)" "unprognostic (1.79e-2)" "unprognostic (9.23e-2)" "unprognostic (2.16e-2)" "unprognostic (9.49e-2)" "unprognostic (3.61e-2)" "unprognostic (2.63e-1)" "unprognostic (7.13e-2)" "unprognostic (3.33e-3)" "unprognostic (9.18e-3)" "unprognostic (1.99e-1)" "unprognostic (1.07e-1)" "unprognostic (8.67e-2)" "unprognostic (1.70e-2)" "unprognostic (2.12e-1)" "unprognostic (6.26e-2)" "unprognostic (4.36e-2)" "unprognostic (1.11e-1)" "unprognostic (1.80e-1)" "unprognostic (2.30e-1)" "unprognostic (1.36e-1)" "unprognostic (3.64e-1)" ENDOD1 KIAA0830 ENSG00000149218 "Endonuclease domain containing 1" O94919 11 95089846-95132645 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Platelets: 695.2" "Cell type enhanced" "Detected in all" "oligodendrocyte: 209.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008932, HPA010517" Enhanced Approved "Nuclear membrane" "Secreted - unknown location" Immunity NA NA 4800000 "Cluster 14: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 47: Platelets - Hemostasis" 33 "Nuclear membrane" "HPA008932: , HPA010517: " "unprognostic (3.41e-1)" "potential prognostic unfavorable (5.25e-4)" "unprognostic (2.92e-3)" "unprognostic (1.12e-2)" "unprognostic (1.29e-1)" "unprognostic (1.36e-1)" "unprognostic (1.85e-1)" "unprognostic (4.56e-3)" "unprognostic (2.74e-2)" "unprognostic (1.17e-1)" "potential prognostic favorable (3.25e-7)" "unprognostic (3.67e-2)" "unprognostic (1.48e-1)" "unprognostic (5.81e-2)" "unprognostic (5.28e-2)" "unprognostic (2.13e-1)" "unprognostic (1.15e-2)" "unprognostic (1.02e-1)" "unprognostic (3.65e-2)" "unprognostic (1.47e-1)" "unprognostic (2.33e-2)" "unprognostic (2.16e-3)" "unprognostic (2.61e-1)" "unprognostic (1.73e-1)" "unprognostic (3.53e-2)" "unprognostic (1.76e-1)" "unprognostic (8.77e-2)" "unprognostic (1.71e-1)" "unprognostic (2.41e-1)" "unprognostic (2.81e-2)" "unprognostic (7.97e-3)" ENDOG ENSG00000167136 "Endonuclease G" Q14249 9 128818500-128822676 "Plasma proteins, Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 126.7" "Cell type enhanced" "Detected in many" "Fallopian tube ciliated cells: 184.5;Late primary spermatocytes: 121.8;Late spermatids: 232.1;Respiratory ciliated cells: 266.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021335, HPA021830" Approved "Intracellular and membrane" Enzyme NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 107: Ciliated cells - Cilia assembly & function" 21 "HPA021335: , HPA021830: " "unprognostic (4.25e-2)" "unprognostic (1.31e-1)" "unprognostic (1.08e-1)" "unprognostic (6.67e-3)" "unprognostic (8.09e-2)" "unprognostic (1.61e-1)" "unprognostic (4.14e-1)" "unprognostic (5.98e-2)" "unprognostic (4.11e-1)" "unprognostic (4.03e-3)" "unprognostic (3.42e-3)" "unprognostic (1.65e-1)" "potential prognostic favorable (3.78e-5)" "unprognostic (6.59e-2)" "unprognostic (1.81e-1)" "unprognostic (7.55e-3)" "unprognostic (5.18e-2)" "unprognostic (2.76e-2)" "unprognostic (8.29e-2)" "unprognostic (2.79e-2)" "unprognostic (2.55e-1)" "unprognostic (3.30e-2)" "unprognostic (3.87e-2)" "unprognostic (2.25e-1)" "unprognostic (1.42e-1)" "unprognostic (4.52e-1)" "unprognostic (2.95e-1)" "unprognostic (4.13e-2)" "unprognostic (3.68e-2)" "unprognostic (9.04e-2)" "unprognostic (6.80e-2)" ENDOU "P11, PP11, PRSS26" ENSG00000111405 "Endonuclease, poly(U) specific" P21128 12 47709734-47725567 "Predicted secreted proteins" "Endonuclease, Hydrolase, Lyase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 23.2;esophagus: 80.6;vagina: 29.9" "Cell type enriched" "Detected in some" 4 "Esophageal apical cells: 511.8" "Cell type enhanced" "Detected in some" "astrocyte: 3.4;committed oligodendrocyte precursor: 2.1" "Cancer enhanced" "Detected in some" "Head and Neck Squamous Cell Carcinoma (TCGA): 4.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "testis cancer: 4.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA012388, HPA067448" Enhanced "Secreted in other tissues" Enzyme NA NA 13000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" "HPA012388: , HPA067448: " "unprognostic (4.38e-2)" "unprognostic (6.83e-2)" "unprognostic (9.30e-2)" "potential prognostic favorable (8.86e-4)" "unprognostic (1.07e-1)" "unprognostic (5.55e-2)" "unprognostic (8.62e-2)" ENDOV FLJ35220 ENSG00000173818 "Endonuclease V" Q8N8Q3 17 80415165-80438086 "Predicted intracellular proteins" "DNA-binding, Endonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 47: Testis - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 65: Non-specific - Cell growth & division" "unprognostic (1.01e-1)" "unprognostic (3.61e-3)" "unprognostic (1.17e-1)" "unprognostic (2.09e-2)" "unprognostic (4.75e-2)" "unprognostic (2.44e-1)" "unprognostic (1.03e-1)" "unprognostic (1.58e-1)" "unprognostic (1.97e-2)" "unprognostic (2.04e-1)" "unprognostic (1.54e-1)" "unprognostic (5.08e-2)" "unprognostic (3.10e-1)" "unprognostic (1.05e-1)" "unprognostic (1.36e-3)" "unprognostic (1.79e-1)" "unprognostic (5.05e-2)" "unprognostic (3.48e-1)" "unprognostic (8.03e-2)" "unprognostic (7.01e-2)" "unprognostic (1.48e-1)" "unprognostic (5.43e-2)" "potential prognostic unfavorable (4.46e-4)" "unprognostic (7.01e-2)" "unprognostic (2.25e-1)" "unprognostic (6.81e-2)" "unprognostic (2.45e-1)" "unprognostic (3.19e-2)" "potential prognostic unfavorable (7.31e-6)" "unprognostic (2.25e-1)" ENG "CD105, END, HHT1, ORW, ORW1" ENSG00000106991 Endoglin P17813 9 127815013-127854658 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Cell adhesion" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 518.6" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 494.5;Hepatic stellate cells: 264.6;Leydig cells: 764.5;Peritubular myoid cells: 1903.9;Syncytiotrophoblasts: 673.5;Vascular endothelial cells: 642.6" "Cell type enhanced" "Detected in many" "endothelial cell: 451.0;fibroblast: 178.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 19.9;intermediate monocyte: 28.2;myeloid DC: 10.3;NK-cell: 7.6;non-classical monocyte: 22.2" "Group enriched" "Detected in many" 4 "dendritic cells: 10.3;monocytes: 28.2;NK-cells: 7.6" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Prostate - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000096, HPA011862, HPA067440, CAB072873" Enhanced Supported "Plasma membrane" NA NA 43000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 11 "Plasma membrane" "CAB000096: , CAB072873: , HPA011862: , HPA067440: " "unprognostic (1.19e-1)" "unprognostic (1.93e-1)" "unprognostic (3.89e-3)" "unprognostic (7.97e-3)" "unprognostic (2.94e-2)" "unprognostic (2.27e-2)" "unprognostic (4.13e-2)" "unprognostic (1.87e-2)" "unprognostic (5.99e-3)" "unprognostic (1.19e-1)" "validated prognostic favorable (2.31e-7)" "validated prognostic favorable (7.87e-5)" "unprognostic (1.34e-1)" "validated prognostic favorable (1.53e-5)" "validated prognostic favorable (2.80e-4)" "unprognostic (7.58e-2)" "unprognostic (4.91e-2)" "unprognostic (4.32e-3)" "unprognostic (2.33e-1)" "unprognostic (4.71e-2)" "unprognostic (2.13e-1)" "unprognostic (2.84e-2)" "unprognostic (2.71e-1)" "unprognostic (2.64e-1)" "unprognostic (7.10e-2)" "unprognostic (8.68e-2)" "unprognostic (2.03e-1)" "potential prognostic unfavorable (7.45e-4)" "unprognostic (8.01e-2)" "unprognostic (2.22e-1)" "unprognostic (4.65e-2)" ENGASE FLJ21865 ENSG00000167280 Endo-beta-N-acetylglucosaminidase Q8NFI3 17 79074824-79088599 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 68.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021551 Approved Approved Centrosome,Cytosol No No "Cluster 24: Non-specific - Transcription" "Cluster 18: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 55: Myocytes - Oxidative muscle function" Cytosol Centrosome "HPA021551: " "unprognostic (9.83e-2)" "unprognostic (1.24e-1)" "unprognostic (9.53e-3)" "unprognostic (4.43e-2)" "unprognostic (1.05e-1)" "unprognostic (1.05e-2)" "unprognostic (1.97e-1)" "unprognostic (1.75e-1)" "unprognostic (6.13e-2)" "unprognostic (1.35e-1)" "unprognostic (1.12e-3)" "unprognostic (2.50e-1)" "unprognostic (4.47e-2)" "unprognostic (1.46e-3)" "unprognostic (7.31e-2)" "unprognostic (9.48e-3)" "unprognostic (4.84e-1)" "unprognostic (1.19e-1)" "unprognostic (3.19e-2)" "unprognostic (4.65e-2)" "unprognostic (1.35e-2)" "potential prognostic favorable (2.94e-5)" "unprognostic (1.16e-3)" "unprognostic (9.91e-2)" "potential prognostic favorable (6.34e-5)" "unprognostic (1.70e-2)" "unprognostic (3.10e-2)" "unprognostic (2.64e-3)" "unprognostic (4.92e-1)" "unprognostic (3.81e-2)" "unprognostic (1.86e-1)" ENHO "C9orf165, UNQ470" ENSG00000168913 "Energy homeostasis associated" Q6UWT2 9 34521043-34522990 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 22 "brain: 589.2" "Cell type enhanced" "Detected in many" "Astrocytes: 95.3;Bergmann glia: 122.2;cDC: 37.7;Müller glia: 68.5;Oligodendrocyte progenitor cells: 51.3;Prostatic glandular cells: 38.3;Schwann cells: 26.0;Undifferentiated spermatogonia: 26.6" "Cell type enhanced" "Detected in all" "astrocyte: 98.6;Bergmann glia: 208.9" "Cancer enriched" "Detected in many" 4 "Glioblastoma Multiforme (TCGA): 89.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 8 "myeloid DC: 28.1" "Lineage enriched" "Detected in many" 8 "dendritic cells: 28.1" "Cancer enhanced" "Detected in many" "Neuroblastoma: 11.2" "Prostate - Prostate glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042575 Approved "Secreted in brain" "No annotated function" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 78: Brain - Neuronal signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 11: Muller glia cells - Retinal homeostasis" "HPA042575: " "unprognostic (4.74e-2)" "unprognostic (1.17e-1)" "unprognostic (1.58e-1)" "unprognostic (1.85e-2)" "unprognostic (2.23e-1)" "unprognostic (6.78e-2)" "potential prognostic favorable (5.93e-5)" "unprognostic (5.39e-2)" "unprognostic (2.24e-1)" "unprognostic (8.17e-2)" "unprognostic (4.19e-2)" "unprognostic (1.19e-3)" "unprognostic (4.81e-2)" "unprognostic (2.35e-2)" "unprognostic (2.77e-1)" "potential prognostic favorable (4.59e-4)" "unprognostic (8.92e-2)" "unprognostic (1.87e-3)" "unprognostic (7.29e-2)" "unprognostic (1.85e-1)" "unprognostic (1.34e-1)" ENKD1 "C16orf48, DKFZP434A1319, FBB11" ENSG00000124074 "Enkurin domain containing 1" Q9H0I2 16 67662945-67667265 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 40.4;Endometrial ciliated cells: 42.7;Epididymal efferent duct ciliated cells: 49.9;Fallopian tube ciliated cells: 74.7;Respiratory ciliated cells: 81.7" "Cell type enhanced" "Detected in all" "ependymal cell: 35.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041163, HPA041478" Approved Supported "Plasma membrane,Primary cilium,Centrosome,Basal body" NA No "Cluster 2: Dendritic cells - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 2: Neurons - Nucleosome" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 107: Ciliated cells - Cilia assembly & function" 171 "Plasma membrane, Centrosome, Basal body" "Primary cilium" "HPA041163: , HPA041478: " "unprognostic (7.44e-2)" "unprognostic (7.09e-2)" "unprognostic (7.24e-2)" "unprognostic (1.54e-3)" "unprognostic (2.53e-2)" "unprognostic (1.70e-1)" "unprognostic (1.36e-2)" "unprognostic (1.57e-1)" "unprognostic (1.86e-1)" "unprognostic (6.59e-2)" "unprognostic (4.55e-2)" "potential prognostic favorable (3.48e-5)" "unprognostic (5.67e-3)" "unprognostic (1.32e-1)" "unprognostic (1.25e-1)" "unprognostic (1.29e-2)" "unprognostic (2.53e-1)" "unprognostic (6.56e-2)" "unprognostic (7.72e-2)" "unprognostic (1.67e-1)" "unprognostic (5.53e-2)" "unprognostic (5.10e-2)" "unprognostic (2.87e-1)" "unprognostic (2.07e-1)" "unprognostic (3.18e-3)" "unprognostic (3.65e-1)" "unprognostic (2.62e-1)" "unprognostic (1.97e-1)" "unprognostic (1.52e-2)" ENKUR "C10orf63, CFAP106, enkurin, MGC26778" ENSG00000151023 "Enkurin, TRPC channel interacting protein" Q8TC29 10 24981979-25062279 "Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 11.3;choroid plexus: 15.8;fallopian tube: 41.0" "Cell type enhanced" "Detected in many" "Early spermatids: 67.7;Endometrial ciliated cells: 159.6;Ependymal cells: 165.9;Epididymal efferent duct ciliated cells: 183.8;Fallopian tube ciliated cells: 296.5;Late primary spermatocytes: 104.3;Platelets: 172.2;Respiratory ciliated cells: 386.8" "Cell type enhanced" "Detected in many" "ependymal cell: 194.3" "Group enriched" "Detected in many" 4 "Glioblastoma Multiforme (TCGA): 14.9;Uterine Corpus Endometrial Carcinoma (TCGA): 8.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 2.7" "Lineage enriched" "Detected in single" 9 "granulocytes: 2.7" "Cancer enhanced" "Detected in some" "Rhabdoid: 2.4" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037593, HPA037594, HPA061503" Enhanced Supported "Cytosol,Mid piece,Principal piece" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 107: Ciliated cells - Cilia assembly & function" 11 "Mid piece" "Cytosol, Principal piece" "HPA037593: , HPA037594: , HPA061503: " "unprognostic (1.13e-1)" "unprognostic (5.92e-3)" "unprognostic (2.39e-1)" "unprognostic (9.20e-2)" "unprognostic (1.42e-2)" "unprognostic (4.38e-1)" "unprognostic (2.40e-1)" "unprognostic (1.20e-1)" "unprognostic (1.43e-1)" "unprognostic (1.63e-2)" "unprognostic (1.12e-1)" "unprognostic (7.79e-2)" "unprognostic (2.60e-2)" "potential prognostic unfavorable (2.38e-4)" "unprognostic (1.14e-1)" "unprognostic (1.16e-1)" ENO1 "ENO1L1, MBP-1, MPB1, PPH" ENSG00000074800 "Enolase 1" P06733 1 8861000-8879190 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glycolysis, Plasminogen activation, Transcription, Transcription regulation" "DNA-binding, Lyase, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 2123.3;Esophageal basal cells: 2585.6;Esophageal suprabasal cells: 2329.2;Extravillous trophoblasts: 2438.6;Migrating cytotrophoblasts: 2045.2;Müller glia: 2322.9;Ocular epithelial cells: 1811.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018614, HPA068284, HPA068721, CAB069394, CAB080034" Supported Enhanced "Plasma membrane,Cytosol" NA NA 280000000 "Cluster 33: Non-specific - ATP binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 15: Kidney cancer - Membrane components" "Cluster 11: Muller glia cells - Retinal homeostasis" 95 "Plasma membrane, Cytosol" "CAB018614: , CAB069394: , CAB080034: , HPA068284: , HPA068721: " "potential prognostic unfavorable (1.29e-4)" "potential prognostic unfavorable (6.67e-4)" "unprognostic (1.73e-1)" "unprognostic (5.66e-3)" "unprognostic (2.31e-3)" "unprognostic (2.32e-1)" "potential prognostic unfavorable (4.46e-4)" "unprognostic (3.80e-2)" "unprognostic (1.03e-2)" "potential prognostic unfavorable (7.17e-7)" "potential prognostic favorable (1.76e-5)" "unprognostic (1.36e-2)" "unprognostic (1.91e-2)" "validated prognostic unfavorable (8.23e-8)" "validated prognostic unfavorable (1.25e-8)" "potential prognostic unfavorable (4.92e-4)" "unprognostic (1.23e-3)" "unprognostic (3.51e-1)" "unprognostic (1.16e-2)" "unprognostic (7.15e-3)" "unprognostic (2.84e-2)" "unprognostic (6.59e-3)" "unprognostic (4.28e-2)" "unprognostic (9.51e-2)" "unprognostic (1.93e-1)" "unprognostic (1.21e-2)" "unprognostic (7.46e-2)" "unprognostic (7.70e-2)" "unprognostic (2.82e-1)" "unprognostic (2.81e-1)" "unprognostic (6.99e-2)" ENO2 NSE ENSG00000111674 "Enolase 2" P09104 12 6913745-6923698 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis Lyase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "brain: 857.9;retina: 1573.2" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 165.6;Brain inhibitory neurons: 124.1;Cone photoreceptor cells: 360.2;Other brain neurons: 131.7;Retinal bipolar cells: 164.1;Retinal horizontal cells: 198.3;Rod photoreceptor cells: 468.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 9.9;MAIT T-cell: 11.4;memory B-cell: 6.8;memory CD4 T-cell: 13.1;memory CD8 T-cell: 11.4;naive B-cell: 4.5;naive CD4 T-cell: 8.2;naive CD8 T-cell: 8.6;neutrophil: 7.0;T-reg: 7.5" "Group enriched" "Detected in many" 7 "B-cells: 6.8;granulocytes: 7.0;T-cells: 13.1" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen), Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000063, HPA068284, HPA068721, CAB073539, CAB079023" Enhanced Supported Enhanced "Plasma membrane,Cytosol" NA NA 47000000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 79: Photoreceptor cells - Phototransduction" 12 "Plasma membrane, Cytosol" "CAB000063: , CAB073539: , CAB079023: , HPA068284: , HPA068721: " "potential prognostic favorable (6.50e-4)" "unprognostic (2.31e-1)" "unprognostic (1.22e-1)" "unprognostic (4.55e-2)" "unprognostic (1.57e-3)" "unprognostic (7.86e-2)" "potential prognostic unfavorable (9.52e-4)" "unprognostic (2.33e-1)" "unprognostic (1.73e-2)" "unprognostic (4.55e-3)" "potential prognostic unfavorable (6.20e-4)" "unprognostic (3.11e-3)" "unprognostic (1.61e-2)" "unprognostic (1.03e-3)" "unprognostic (1.45e-1)" "unprognostic (8.18e-2)" "unprognostic (3.68e-2)" "unprognostic (2.06e-1)" "unprognostic (2.21e-1)" "unprognostic (1.71e-1)" "unprognostic (1.32e-1)" "unprognostic (3.16e-1)" "potential prognostic unfavorable (6.28e-4)" "unprognostic (5.19e-2)" "unprognostic (1.25e-1)" "unprognostic (1.82e-1)" "unprognostic (1.05e-1)" "unprognostic (9.28e-2)" "unprognostic (3.58e-1)" "unprognostic (1.14e-2)" "unprognostic (9.17e-2)" ENO3 ENSG00000108515 "Enolase 3" P13929 17 4948092-4957131 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis Lyase "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 27 "skeletal muscle: 13830.4;tongue: 10054.3" "Cell type enhanced" "Detected in many" "Adipocytes: 62.2;Cardiomyocytes: 212.4;Epicardial cells: 150.1;Mesothelial cells: 87.0;Myonuclei: 163.8;Plasma cells: 82.2;Thymic myoid cells: 444.6;Thymocytes: 65.2" "Cell type enhanced" "Detected in many" "upper rhombic lip: 12.2" "Cancer enhanced" "Detected in all" "Uterine Corpus Endometrial Carcinoma (TCGA): 64.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000793, HPA068284, HPA068721" Enhanced Enhanced "Plasma membrane,Cytosol" Yes No 65000000 "Cluster 29: Non-specific - Unknown function" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 25: Non-specific - Transcription" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 11 "Plasma membrane, Cytosol" "HPA000793: , HPA068284: , HPA068721: " "unprognostic (4.90e-3)" "unprognostic (1.07e-1)" "unprognostic (1.45e-1)" "unprognostic (2.83e-2)" "unprognostic (3.41e-3)" "unprognostic (2.84e-3)" "unprognostic (5.13e-2)" "unprognostic (1.93e-1)" "unprognostic (1.05e-1)" "unprognostic (5.96e-2)" "unprognostic (4.88e-3)" "unprognostic (6.38e-2)" "unprognostic (1.72e-2)" "unprognostic (5.00e-2)" "unprognostic (9.82e-2)" "unprognostic (1.01e-2)" "unprognostic (6.83e-2)" "unprognostic (1.53e-2)" "unprognostic (2.48e-2)" "unprognostic (1.84e-1)" "unprognostic (8.99e-3)" "unprognostic (2.52e-3)" "unprognostic (1.23e-3)" "unprognostic (1.44e-1)" "unprognostic (2.04e-2)" "unprognostic (1.85e-1)" "unprognostic (4.59e-2)" "unprognostic (1.69e-2)" "unprognostic (1.18e-1)" "unprognostic (2.77e-2)" "unprognostic (3.94e-1)" ENO4 "AC023283.3, C10orf134" ENSG00000188316 "Enolase 4" A6NNW6 10 116849499-116911788 "Enzymes, Predicted intracellular proteins" Glycolysis Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 5.2;fallopian tube: 4.7" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 116.3;cDC: 96.4;Choroid plexus epithelial cells: 80.3;Ependymal cells: 254.9;Epicardial cells: 354.8;Fallopian tube ciliated cells: 106.6;Oligodendrocytes: 115.6;Respiratory ciliated cells: 104.9" "Cell type enhanced" "Detected in many" "ependymal cell: 273.3;oligodendrocyte: 198.8" "Cancer enhanced" "Detected in single" "Uterine Corpus Endometrial Carcinoma (TCGA): 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA037938 Enhanced Approved Vesicles,Cytosol NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 11: White matter - Signal transduction" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" Vesicles Cytosol "HPA037938: " "potential prognostic unfavorable (1.16e-4)" "unprognostic (1.34e-1)" "unprognostic (2.57e-2)" ENOPH1 "E1, MASA, mtnC" ENSG00000145293 "Enolase-phosphatase 1" Q9UHY7 4 82430590-82461177 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Amino-acid biosynthesis, Methionine biosynthesis" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 129.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 117.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004985, HPA044607, HPA050480" Enhanced Approved "Nucleoplasm,Nucleoli,Nuclear bodies" NA NA 300000 "Cluster 1: T-cells - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 9 Nucleoplasm "Nucleoli, Nuclear bodies" "CAB004985: , HPA044607: , HPA050480: " "unprognostic (5.56e-2)" "unprognostic (6.31e-3)" "unprognostic (7.44e-3)" "unprognostic (8.28e-2)" "unprognostic (2.11e-2)" "unprognostic (3.75e-3)" "unprognostic (1.76e-1)" "unprognostic (1.44e-1)" "unprognostic (7.20e-3)" "potential prognostic unfavorable (3.71e-5)" "potential prognostic favorable (1.35e-5)" "unprognostic (1.60e-2)" "unprognostic (1.15e-1)" "potential prognostic unfavorable (1.06e-5)" "unprognostic (1.62e-3)" "unprognostic (6.00e-3)" "unprognostic (1.47e-2)" "unprognostic (1.47e-1)" "unprognostic (2.46e-2)" "unprognostic (3.00e-1)" "unprognostic (1.92e-1)" "unprognostic (6.22e-2)" "unprognostic (8.67e-2)" "unprognostic (9.73e-2)" "unprognostic (8.11e-2)" "unprognostic (7.24e-2)" "unprognostic (8.18e-2)" "unprognostic (6.22e-2)" "unprognostic (2.39e-1)" "unprognostic (9.49e-2)" "unprognostic (7.55e-2)" ENOSF1 "FUCD, HSRTSBETA, rTS, TYMSAS" ENSG00000132199 "Enolase superfamily member 1" Q7L5Y1 18 670318-712662 "Enzymes, Predicted intracellular proteins" "Isomerase, Lyase" "Dyskeratosis congenita" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cell type enhanced" "Detected in all" "oligodendrocyte: 304.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" HPA047829 Enhanced NA NA 3700 "Cluster 3: Non-specific - Nuclear processes" "Cluster 72: Kidney - Transmembrane transport" "Cluster 11: White matter - Signal transduction" "Cluster 13: Non-specific - Mixed function" "Cluster 7: Non-specific - Transcription" "HPA047829: " "unprognostic (1.75e-2)" "unprognostic (1.38e-1)" "unprognostic (8.01e-2)" "unprognostic (1.53e-3)" "potential prognostic favorable (5.27e-4)" "unprognostic (9.79e-2)" "unprognostic (7.34e-2)" "unprognostic (4.53e-2)" "unprognostic (2.44e-1)" "unprognostic (1.33e-1)" "validated prognostic favorable (3.54e-5)" "validated prognostic favorable (1.27e-4)" "potential prognostic favorable (1.03e-4)" "unprognostic (2.23e-1)" "unprognostic (4.69e-2)" "unprognostic (4.08e-2)" "unprognostic (2.02e-2)" "unprognostic (2.01e-1)" "unprognostic (2.57e-2)" "unprognostic (1.02e-2)" "potential prognostic favorable (2.74e-4)" "potential prognostic favorable (9.81e-4)" "unprognostic (1.22e-2)" "unprognostic (1.94e-2)" "unprognostic (4.82e-1)" "unprognostic (3.39e-1)" "unprognostic (1.35e-2)" "unprognostic (4.20e-1)" "unprognostic (4.99e-2)" "unprognostic (2.19e-1)" "unprognostic (3.04e-1)" ENOX1 "cCNOX, CNOX, FLJ10094, PIG38" ENSG00000120658 "Ecto-NOX disulfide-thiol exchanger 1" Q8TC92 13 43213130-43786972 "Predicted intracellular proteins" "Biological rhythms, Electron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 470.5;Brain inhibitory neurons: 519.6;Cardiomyocytes: 333.9;Early spermatids: 357.7;Late spermatids: 418.0;Loop of henle epithelial cells: 338.1;Medullary thymic epithelial cells: 420.0;Oligodendrocytes: 793.2;Other brain neurons: 300.6;Retinal amacrine cells: 550.5;Retinal ganglion cells: 378.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 13.8" "Adipose visceral - Mesothelial cells, Adrenal gland - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038355 Approved Supported "Plasma membrane" "Intracellular and membrane" Transport NA NA "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 82: Dendritic cells - Antigen presentation" 6 "Plasma membrane" "HPA038355: " "unprognostic (7.66e-2)" "unprognostic (8.65e-2)" "unprognostic (1.22e-1)" "unprognostic (7.76e-3)" "unprognostic (7.10e-2)" "potential prognostic favorable (7.21e-4)" "unprognostic (1.83e-1)" "unprognostic (2.93e-3)" "unprognostic (4.25e-1)" "unprognostic (2.36e-1)" "unprognostic (5.76e-3)" "unprognostic (3.92e-2)" "unprognostic (1.58e-1)" "unprognostic (1.58e-1)" "unprognostic (1.41e-1)" "unprognostic (5.19e-3)" "unprognostic (2.25e-1)" "unprognostic (1.49e-3)" "unprognostic (8.81e-2)" ENOX2 "APK1, COVA1, tNOX" ENSG00000165675 "Ecto-NOX disulfide-thiol exchanger 2" Q16206 X 130622325-130903234 "Predicted intracellular proteins" "Biological rhythms, Electron transport, Growth regulation, Transport" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000514, HPA003027" Uncertain Approved "Plasma membrane,Cytosol" "Intracellular and membrane" Transport NA NA "Cluster 41: Basophils - Unknown function" "Cluster 35: Non-specific - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 36: Non-specific - mRNA processing" "Cluster 82: Dendritic cells - Antigen presentation" Cytosol "Plasma membrane" "HPA000514: , HPA003027: " "unprognostic (5.19e-1)" "unprognostic (9.77e-3)" "unprognostic (2.19e-1)" "unprognostic (1.38e-1)" "unprognostic (2.49e-1)" "unprognostic (5.46e-2)" "unprognostic (3.08e-1)" "unprognostic (1.16e-2)" "unprognostic (2.04e-1)" "potential prognostic unfavorable (7.48e-6)" "potential prognostic favorable (9.99e-7)" "unprognostic (4.92e-2)" "unprognostic (5.50e-2)" "unprognostic (3.08e-2)" "unprognostic (1.37e-1)" "unprognostic (4.10e-1)" "unprognostic (6.53e-3)" "unprognostic (2.49e-1)" "unprognostic (7.58e-2)" "unprognostic (3.21e-2)" "unprognostic (1.30e-1)" "unprognostic (1.43e-1)" "unprognostic (2.23e-2)" "unprognostic (3.63e-1)" "unprognostic (4.35e-2)" "unprognostic (4.13e-2)" "unprognostic (2.08e-3)" "unprognostic (6.51e-2)" "unprognostic (4.58e-2)" "unprognostic (9.89e-2)" "unprognostic (1.16e-1)" ENPEP "CD249, gp160" ENSG00000138792 "Glutamyl aminopeptidase" Q07075 4 110365733-110565285 "CD markers, Enzymes, Plasma proteins, Predicted membrane proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 154.1;kidney: 84.1" "Group enriched" "Detected in many" 4 "Enterocytes: 922.1;Podocytes: 1667.1;Proximal tubule cells: 455.1" "Group enriched" "Detected in many" 4 "ependymal cell: 264.6;pericyte: 81.0" "Group enriched" "Detected in many" 8 "Kidney Renal Clear Cell Carcinoma (TCGA): 93.2;Kidney Renal Papillary Cell Carcinoma (TCGA): 24.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 5.3;Kidney cancer: 14.1" "Adipose subcutaneous - Endothelial cells, Adrenal gland - Fibroblasts, Breast - Endothelial cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Pituitary gland - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA005128 Enhanced NA NA 25000000 "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 57: Podocytes - Glomerular filtration" "HPA005128: " "unprognostic (2.56e-1)" "unprognostic (2.35e-3)" "unprognostic (3.39e-1)" "unprognostic (7.02e-3)" "unprognostic (3.76e-1)" "unprognostic (3.44e-1)" "unprognostic (3.94e-1)" "unprognostic (1.87e-1)" "unprognostic (1.43e-1)" "potential prognostic favorable (5.27e-9)" "unprognostic (4.07e-3)" "potential prognostic favorable (6.81e-4)" "unprognostic (2.14e-2)" "potential prognostic favorable (4.67e-5)" "unprognostic (1.08e-1)" "unprognostic (3.26e-2)" "unprognostic (8.87e-2)" "potential prognostic unfavorable (2.87e-4)" "unprognostic (2.09e-2)" "unprognostic (1.96e-2)" "unprognostic (7.41e-2)" "unprognostic (1.67e-3)" "unprognostic (8.38e-2)" "unprognostic (5.73e-2)" "potential prognostic unfavorable (2.70e-4)" "unprognostic (6.37e-2)" "unprognostic (3.24e-2)" ENPP1 "M6S1, NPPS, PC-1, PCA1, PDNP1" ENSG00000197594 "Ectonucleotide pyrophosphatase/phosphodiesterase 1" P22413 6 131808016-131895155 "CD markers, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins" Biomineralization Hydrolase "Diabetes mellitus, Disease variant, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 40.7" "Cell type enhanced" "Detected in many" "Adipocytes: 91.8;Decidual stromal cells: 101.2;Endometrial stromal cells: 126.0;Hepatocytes: 216.8;Lactotrophs: 426.1;Medullary thymic epithelial cells: 110.4;Pancreatic acinar cells: 108.2;Peritubular myoid cells: 121.3;Somatotrophs: 290.9" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 83.2;cerebellar inhibitory: 46.9" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 18.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 1.5" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Fibroblasts, Liver - Hepatocytes, Pituitary gland - Somatotropes, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032904, HPA062066" Enhanced "Secreted - unknown location" Enzyme NA NA 1600000 "Cluster 35: Neutrophils - Protein binding" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 8 "CAB032904: , HPA062066: " "unprognostic (2.75e-1)" "unprognostic (1.09e-1)" "unprognostic (1.49e-1)" "potential prognostic unfavorable (7.86e-4)" "unprognostic (1.55e-1)" "unprognostic (3.07e-2)" "unprognostic (3.90e-1)" "unprognostic (1.80e-2)" "unprognostic (1.79e-1)" "unprognostic (3.62e-3)" "unprognostic (1.40e-1)" "unprognostic (1.91e-1)" "unprognostic (3.28e-2)" "unprognostic (1.34e-1)" "unprognostic (2.86e-1)" "potential prognostic unfavorable (3.95e-4)" "unprognostic (1.10e-1)" "unprognostic (2.80e-1)" "unprognostic (9.70e-2)" "potential prognostic unfavorable (6.75e-4)" "unprognostic (1.94e-1)" "unprognostic (1.57e-1)" "unprognostic (3.26e-1)" "unprognostic (1.79e-1)" "unprognostic (5.56e-2)" "unprognostic (4.92e-2)" "unprognostic (1.91e-1)" "unprognostic (3.53e-1)" "unprognostic (8.97e-2)" "unprognostic (1.06e-2)" ENPP2 "ATX, PD-IALPHA, PDNP2" ENSG00000136960 "Ectonucleotide pyrophosphatase/phosphodiesterase 2" Q13822 8 119557086-119673453 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Chemotaxis, Lipid degradation, Lipid metabolism" Hydrolase "Cancer-related genes, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "choroid plexus: 1260.1" "Group enriched" "Detected in many" 7 "Choroid plexus epithelial cells: 2401.3;Oligodendrocytes: 1108.0;Retinal pigment epithelial cells: 2391.5" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 1864.0;oligodendrocyte: 1518.1" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 260.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "basophil: 54.0" "Lineage enriched" "Detected in many" 8 "granulocytes: 54.0" "Cancer enhanced" "Detected in many" "Neuroblastoma: 88.1" "Breast - Endothelial cells, Skeletal muscle - Endothelial cells, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023700, HPA053652" Approved Approved "Nucleoplasm,Golgi apparatus,Actin filaments" "Secreted to blood" Enzyme NA NA 290000000 "Cluster 41: Basophils - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" "Nucleoplasm, Golgi apparatus" "Actin filaments" "HPA023700: , HPA053652: " "unprognostic (6.64e-2)" "unprognostic (3.39e-2)" "potential prognostic favorable (3.92e-4)" "unprognostic (1.84e-1)" "unprognostic (5.10e-2)" "unprognostic (6.86e-3)" "unprognostic (1.62e-1)" "unprognostic (2.14e-1)" "unprognostic (2.57e-1)" "unprognostic (1.15e-2)" "potential prognostic favorable (2.97e-5)" "unprognostic (3.04e-2)" "unprognostic (6.53e-2)" "unprognostic (4.16e-3)" "unprognostic (2.82e-2)" "unprognostic (1.51e-2)" "unprognostic (1.06e-1)" "unprognostic (1.94e-3)" "unprognostic (1.34e-1)" "unprognostic (1.83e-1)" "unprognostic (1.34e-1)" "potential prognostic favorable (7.61e-5)" "unprognostic (7.87e-3)" "unprognostic (7.17e-2)" "unprognostic (5.67e-2)" "unprognostic (1.41e-1)" "unprognostic (3.86e-2)" "unprognostic (3.82e-2)" "unprognostic (4.27e-2)" "unprognostic (4.67e-2)" "unprognostic (1.29e-2)" ENPP3 "B10, CD203c, gp130RB13-6, PD-IBETA, PDNP3" ENSG00000154269 "Ectonucleotide pyrophosphatase/phosphodiesterase 3" O14638 6 131628442-131747418 "CD markers, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 30.3;intestine: 41.9" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 118.0;Endometrial ciliated cells: 125.0;Endometrial glandular cells: 375.7;Endometrial luminal cells: 934.0;Enterocytes: 169.4;Epididymal efferent duct absorptive cells: 103.8;Lacrimal acinar cells: 156.7;Mast cells: 393.7;Medullary thymic epithelial cells: 189.6;Proximal tubule cells: 148.6" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in many" 11 "Kidney Renal Clear Cell Carcinoma (TCGA): 138.1" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 86 "basophil: 30.6" "Lineage enriched" "Detected in single" 86 "granulocytes: 30.6" "Cancer enhanced" "Detected in some" "Bone cancer: 4.1;Kidney cancer: 4.0;Leukemia: 6.2" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Mast cells, Skeletal muscle - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA043772 Enhanced "Secreted - unknown location" Enzyme NA NA 340000 "Cluster 46: Basophils - Proteolysis" "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 2: Neurons - Nucleosome" "Cluster 47: Leukemia - Hemostasis" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" "HPA043772: " "unprognostic (2.21e-1)" "unprognostic (6.86e-3)" "unprognostic (2.91e-2)" "unprognostic (1.88e-1)" "unprognostic (4.47e-2)" "unprognostic (2.27e-2)" "potential prognostic favorable (1.57e-7)" "unprognostic (4.73e-2)" "unprognostic (9.67e-2)" "unprognostic (1.08e-1)" "unprognostic (7.65e-2)" "unprognostic (4.73e-3)" "unprognostic (3.79e-2)" "unprognostic (8.41e-2)" "unprognostic (4.65e-2)" "unprognostic (4.76e-1)" "unprognostic (8.40e-2)" "unprognostic (6.39e-2)" "unprognostic (1.93e-1)" "unprognostic (3.07e-1)" ENPP4 "AP3Aase, KIAA0879, NPP4" ENSG00000001561 "Ectonucleotide pyrophosphatase/phosphodiesterase 4" Q9Y6X5 6 46129989-46146688 "Enzymes, Predicted membrane proteins" "Blood coagulation, Hemostasis" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 126.2;Neutrophil progenitors: 151.9;Oligodendrocytes: 100.9;Salivary duct cells: 154.0" "Cell type enhanced" "Detected in all" "oligodendrocyte: 134.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016594 Approved NA NA 22000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 11 "HPA016594: " "unprognostic (2.80e-3)" "unprognostic (3.31e-2)" "unprognostic (1.22e-1)" "unprognostic (3.11e-2)" "unprognostic (1.04e-1)" "unprognostic (6.38e-2)" "unprognostic (3.36e-1)" "unprognostic (3.71e-2)" "unprognostic (1.58e-1)" "unprognostic (8.10e-2)" "validated prognostic favorable (9.86e-9)" "validated prognostic favorable (8.91e-4)" "unprognostic (1.19e-1)" "unprognostic (1.25e-1)" "unprognostic (7.98e-2)" "unprognostic (9.59e-3)" "unprognostic (2.23e-2)" "potential prognostic unfavorable (6.48e-4)" "unprognostic (3.14e-2)" "unprognostic (1.66e-1)" "unprognostic (1.30e-3)" "unprognostic (1.88e-1)" "unprognostic (1.60e-1)" "unprognostic (2.55e-1)" "unprognostic (1.02e-1)" "unprognostic (1.08e-2)" "unprognostic (2.35e-1)" "unprognostic (1.12e-1)" "unprognostic (2.14e-1)" "unprognostic (1.75e-2)" "unprognostic (2.51e-1)" ENPP5 ENSG00000112796 "Ectonucleotide pyrophosphatase/phosphodiesterase family member 5" Q9UJA9 6 46159185-46170980 "Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "epididymis: 230.1" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 394.7;Müller glia: 132.7;Myonuclei: 73.6;Myosatellite cells: 82.4;Pituicytes/FSCs: 205.7;Prostatic glandular cells: 77.9;Retinal pigment epithelial cells: 76.7;Sertoli cells: 114.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 14.9" "Lineage enriched" "Detected in many" 5 "T-cells: 14.9" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Breast - Breast glandular cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Prostate - Prostate glandular cells, Stomach - Parietal cells, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016902 Enhanced Approved Nucleoplasm,Cytosol "Intracellular and membrane" Enzyme NA NA 340000 "Cluster 1: T-cells - Unknown function" "Cluster 22: Epididymis - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 3 Cytosol Nucleoplasm "HPA016902: " "unprognostic (2.79e-2)" "unprognostic (3.53e-2)" "unprognostic (1.75e-2)" "unprognostic (7.08e-2)" "unprognostic (6.10e-2)" "unprognostic (1.51e-2)" "unprognostic (9.15e-2)" "unprognostic (1.57e-1)" "unprognostic (1.73e-1)" "unprognostic (9.97e-3)" "potential prognostic favorable (6.39e-11)" "unprognostic (1.03e-3)" "unprognostic (8.20e-3)" "unprognostic (2.06e-1)" "unprognostic (1.08e-1)" "potential prognostic favorable (9.71e-4)" "unprognostic (3.39e-3)" "unprognostic (3.72e-3)" "unprognostic (1.35e-1)" "unprognostic (3.11e-1)" "unprognostic (1.25e-2)" "unprognostic (1.20e-2)" "unprognostic (1.09e-1)" "unprognostic (1.40e-1)" "unprognostic (1.73e-2)" "unprognostic (5.66e-2)" "unprognostic (3.22e-1)" "unprognostic (6.38e-2)" "unprognostic (4.97e-2)" "unprognostic (2.24e-1)" "unprognostic (5.52e-2)" ENPP6 MGC33971 ENSG00000164303 "Ectonucleotide pyrophosphatase/phosphodiesterase 6" Q6UWR7 4 184088706-184221230 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 27.6;kidney: 28.6;ovary: 15.2" "Group enriched" "Detected in many" 4 "Oligodendrocytes: 110.2;Peritubular myoid cells: 52.1;Pituitary stem cells: 46.6;Proximal tubule cells: 118.1" "Group enriched" "Detected in all" 7 "committed oligodendrocyte precursor: 169.7;fibroblast: 140.7;oligodendrocyte: 159.1" "Cancer enriched" "Detected in some" 5 "Glioblastoma Multiforme (TCGA): 5.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Myeloma: 1.3" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Minor Salivary Gland - Fibroblasts, Pituitary gland - Fibroblasts, Skeletal muscle - Fibroblasts, Testis - Peritubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042740, HPA069197" Enhanced Approved "Golgi apparatus" "Intracellular and membrane" Enzyme NA NA 51000 "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 59: Leukemia - T-cell receptor" "Cluster 88: Proximal tubular cells - Transmembrane transport" 2 "Golgi apparatus" "HPA042740: , HPA069197: " "unprognostic (2.71e-1)" "unprognostic (2.29e-1)" "unprognostic (3.34e-1)" "unprognostic (1.50e-2)" "unprognostic (2.27e-2)" "unprognostic (2.13e-1)" "unprognostic (1.27e-1)" "unprognostic (1.31e-1)" ENPP7 "alk-SMase, NPP7" ENSG00000182156 "Ectonucleotide pyrophosphatase/phosphodiesterase 7" Q6UWV6 17 79730943-79742219 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "intestine: 98.5" "Group enriched" "Detected in some" 6 "Enterocytes: 27.0;Hepatocytes: 14.3" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Liver Hepatocellular Carcinoma (TCGA): 13.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Myeloma: 1.5" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA024603 Approved "Intracellular and membrane" Enzyme NA NA 260000 "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 1: Enterocytes - Absorption and Digestion" 14 "HPA024603: " "potential prognostic favorable (1.09e-5)" "unprognostic (2.99e-2)" "unprognostic (3.10e-1)" "unprognostic (2.11e-1)" "unprognostic (2.53e-1)" ENSA "ARPP-19e, MGC4319, MGC78563, MGC8394" ENSG00000143420 "Endosulfine alpha" O43768 1 150600851-150629612 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1268.4;Esophageal suprabasal cells: 1066.1;Neutrophils: 759.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051294 Uncertain Approved Nucleoplasm,Nucleoli,Microtubules,Cytosol NA NA 1100000 "Cluster 45: Eosinophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 53: Neurons - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 3 "Nucleoplasm, Nucleoli" "Microtubules, Cytosol" "HPA051294: " "unprognostic (2.60e-1)" "potential prognostic unfavorable (7.74e-4)" "unprognostic (5.68e-2)" "unprognostic (1.12e-1)" "unprognostic (1.79e-1)" "unprognostic (1.44e-1)" "unprognostic (1.94e-1)" "unprognostic (2.28e-3)" "unprognostic (2.67e-1)" "unprognostic (1.74e-3)" "unprognostic (1.39e-2)" "unprognostic (3.07e-2)" "unprognostic (3.11e-1)" "unprognostic (7.57e-3)" "unprognostic (2.46e-2)" "unprognostic (3.75e-2)" "unprognostic (3.50e-2)" "unprognostic (1.73e-2)" "unprognostic (5.80e-2)" "unprognostic (5.36e-2)" "unprognostic (1.23e-1)" "unprognostic (1.22e-1)" "unprognostic (7.02e-2)" "unprognostic (2.56e-2)" "unprognostic (2.59e-2)" "unprognostic (1.35e-1)" "unprognostic (1.76e-1)" "unprognostic (1.54e-1)" "unprognostic (1.74e-1)" "unprognostic (3.93e-2)" "unprognostic (2.73e-1)" ENSG00000111780 ENSG00000111780 "Novel protein" 12 120438198-120460006 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 22.9;Colonocytes: 56.0;Enteric stem cells: 30.4;Enteric transient amplifying cells: 43.3;Enterocytes: 63.0;Epididymal clear cells: 20.4;Goblet cells: 28.6;Parietal cells: 26.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" HPA062394 Uncertain Approved "Mitochondria,Principal piece" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 61: BICR 18 - Protein kinases" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" Mitochondria "Principal piece" "HPA062394: " "unprognostic (3.53e-1)" "unprognostic (3.33e-1)" "unprognostic (9.91e-2)" "unprognostic (5.89e-2)" ENSG00000131152 ENSG00000131152 "Novel protein" 16 87302876-87334273 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "skeletal muscle: 4.0" "Cell type enhanced" "Detected in many" "Adipocytes: 19.3;Cardiomyocytes: 39.0;Cone photoreceptor cells: 16.6;Epicardial cells: 9.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" HPA040850 Approved NA NA "Cluster 24: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 23: Non-specific - Transcription" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "HPA040850: " "unprognostic (7.42e-3)" "unprognostic (1.06e-1)" "unprognostic (1.90e-1)" "unprognostic (1.70e-1)" "potential prognostic favorable (6.80e-4)" ENSG00000142539 ENSG00000142539 "Novel protein" 19 50415799-50428409 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.0;plasmacytoid DC: 2.0" "Group enriched" "Detected in many" 15 "B-cells: 1.0;dendritic cells: 2.0" "Not detected" "Not detected" HPA018523 Uncertain NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 35: RS4;11 - Unknown function" "Cluster 82: Dendritic cells - Antigen presentation" "HPA018523: " ENSG00000144785 ENSG00000144785 "Novel protein" 12 56285916-56316059 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 35.2;Myonuclei: 32.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "HPA038466, HPA068007" Uncertain Approved "Nucleoplasm,Centriolar satellite" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 70: Non-specific - Protein processing" "Cluster 23: Choroid plexus - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 55: Myocytes - Oxidative muscle function" "Nucleoplasm, Centriolar satellite" "HPA038466: , HPA068007: " "unprognostic (1.27e-1)" "unprognostic (2.43e-2)" "unprognostic (6.18e-2)" "unprognostic (3.54e-2)" "unprognostic (5.01e-2)" "unprognostic (1.40e-1)" "unprognostic (2.17e-3)" "unprognostic (2.68e-1)" "potential prognostic favorable (7.33e-4)" "unprognostic (9.27e-2)" "unprognostic (7.04e-3)" "unprognostic (2.87e-1)" "unprognostic (4.97e-3)" "unprognostic (9.54e-2)" "unprognostic (3.67e-2)" "unprognostic (4.33e-2)" "unprognostic (1.99e-2)" "unprognostic (2.96e-2)" "unprognostic (4.24e-2)" "unprognostic (1.43e-1)" "unprognostic (5.32e-1)" "unprognostic (2.84e-3)" "unprognostic (1.48e-1)" "unprognostic (1.06e-1)" "unprognostic (1.01e-1)" "unprognostic (2.95e-2)" ENSG00000170846 ENSG00000170846 "Novel protein, similar to Morf4 family associated protein 1" B2RBV5 4 6663396-6676755 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 50.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" "unprognostic (2.42e-2)" "unprognostic (7.64e-2)" "unprognostic (4.70e-2)" "unprognostic (4.94e-2)" "unprognostic (6.45e-3)" "unprognostic (4.44e-1)" "unprognostic (2.76e-2)" "unprognostic (3.58e-2)" "unprognostic (3.22e-1)" "unprognostic (9.65e-3)" "unprognostic (4.04e-2)" "unprognostic (4.36e-2)" "unprognostic (1.50e-1)" "unprognostic (1.93e-1)" "unprognostic (8.36e-3)" "unprognostic (5.79e-2)" "unprognostic (1.69e-3)" "unprognostic (6.83e-2)" "unprognostic (2.25e-1)" "unprognostic (1.56e-1)" "unprognostic (1.99e-1)" "unprognostic (1.86e-2)" "unprognostic (1.68e-2)" "unprognostic (2.17e-1)" "unprognostic (3.49e-2)" "unprognostic (1.12e-1)" "unprognostic (5.01e-1)" "unprognostic (5.61e-2)" "unprognostic (3.57e-1)" ENSG00000173366 ENSG00000173366 "Novel twinfilin, actin-binding protein, homolog 2 (Drosophila) (TWF2) and toll-like receptor 9 (TLR9) protein" 3 52221081-52231190 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Cholangiocytes: 2.0;Enterocytes: 1.1;Neuroendocrine cells: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 15: Non-specific - Protein processing" 3 ENSG00000173867 ENSG00000173867 "Novel transcript" 15 88459501-88546585 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 29.1;Cardiomyocytes: 93.6;Epicardial cells: 18.2;Thyrotrophs: 13.2" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" HPA048873 Uncertain Approved "Nucleoplasm,Microtubules,Cytokinetic bridge" Yes NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 75: Ovary - Mixed function" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 58: Non-specific - Nuclear processes" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" Microtubules "Nucleoplasm, Cytokinetic bridge" "HPA048873: " "unprognostic (5.81e-2)" "unprognostic (6.12e-2)" ENSG00000187186 ENSG00000187186 "Novel protein" 9 34664163-34666112 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 94.4;testis: 280.6" "Cell type enriched" "Detected in many" 4 "Late spermatids: 2680.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 18.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Testis - Late spermatids" "Low region specificity" "Detected in all" HPA069617 Enhanced Approved "Nucleoli,Endoplasmic reticulum,Vesicles" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 67: Testis - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" Vesicles "Nucleoli, Endoplasmic reticulum" "HPA069617: " "unprognostic (1.85e-2)" "unprognostic (3.21e-3)" "unprognostic (3.75e-3)" "unprognostic (6.13e-3)" "unprognostic (1.71e-1)" "validated prognostic unfavorable (1.27e-4)" "validated prognostic unfavorable (2.67e-5)" "unprognostic (9.32e-2)" "unprognostic (2.32e-1)" "unprognostic (7.88e-3)" "unprognostic (4.65e-2)" "potential prognostic favorable (7.91e-7)" "unprognostic (1.64e-2)" "unprognostic (4.53e-2)" "unprognostic (1.01e-2)" "unprognostic (1.29e-1)" "unprognostic (3.41e-1)" "unprognostic (1.92e-2)" "unprognostic (3.64e-2)" "unprognostic (4.44e-3)" "unprognostic (4.09e-1)" "unprognostic (8.23e-2)" "unprognostic (1.21e-1)" "unprognostic (5.16e-2)" "unprognostic (3.34e-3)" "unprognostic (1.54e-1)" "unprognostic (1.03e-1)" "unprognostic (3.51e-2)" "unprognostic (1.07e-1)" ENSG00000188897 ENSG00000188897 "Novel lipoprotein amino terminal region containing protein" 16 11359845-11527247 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 17.7" "Cell type enriched" "Detected in many" 7 "Neutrophils: 1842.5" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 24.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 12 "neutrophil: 3.5" "Lineage enriched" "Detected in single" 12 "granulocytes: 3.5" "Cancer enhanced" "Detected in some" "Myeloma: 3.8" "Adipose visceral - Neutrophils, Minor Salivary Gland - Minor salivary glandular cells, Skin - Keratinocyte (granular), Spleen - Neutrophils_2" "Not detected" "Not detected" HPA042154 Uncertain NA NA "Cluster 5: Spleen - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 24: Neutrophils - Innate immunity signal integration" "HPA042154: " "unprognostic (4.61e-2)" "potential prognostic favorable (4.21e-4)" "unprognostic (4.66e-3)" "unprognostic (3.07e-2)" "unprognostic (1.06e-3)" "unprognostic (3.15e-1)" "unprognostic (3.95e-2)" "unprognostic (3.59e-1)" ENSG00000196826 ENSG00000196826 "Novel zinc finger protein" 19 12461559-12551474 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "Late spermatids: 26.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in single" "Testicular Germ Cell Tumor (TCGA): 1.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 29: Neutrophils - Innate immune cellular maintenance" "unprognostic (5.58e-2)" "unprognostic (3.14e-1)" "unprognostic (1.17e-2)" "unprognostic (4.18e-1)" ENSG00000197991 ENSG00000197991 "Novel protein" 13 61409858-61427849 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA062669 Approved "Vesicles,Cytokinetic bridge" Yes NA "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" Vesicles "Cytokinetic bridge" "HPA062669: " "unprognostic (5.74e-2)" "unprognostic (7.91e-3)" ENSG00000198211 ENSG00000198211 "Novel protein (MC1R-TUBB3 readthrough)" 16 89919165-89936092 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 10 "testis: 5.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Skin Cutaneous Melanoma (TCGA): 2.9" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "skin cancer: 1.9" "CAB011512, HPA043640, HPA046280" Uncertain Approved "Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Primary cilium tip,Basal body,Flagellar centriole,Principal piece,End piece" Yes NA "Cluster 79: Testis - Spermatogenesis" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 58: Mast cells - Allergic inflammatory responses" 1 Microtubules "Cytokinetic bridge, Mitotic spindle, Primary cilium, Primary cilium tip, Basal body, Flagellar centriole, Principal piece, End piece" "CAB011512: , HPA043640: , HPA046280: " "unprognostic (5.56e-2)" "unprognostic (3.64e-1)" ENSG00000203546 ENSG00000203546 "Novel protein" 14 31334312-31457441 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "adipose tissue: 1.1;skeletal muscle: 1.1" "Cell type enhanced" "Detected in many" "Myonuclei: 39.8;Oligodendrocyte progenitor cells: 40.0;Oligodendrocytes: 63.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "NK-cell: 1.3" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral)" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 66: Non-specific - Mitochondria" "Cluster 89: Adipocytes - Lipid metabolism" "unprognostic (9.56e-2)" "unprognostic (6.65e-2)" "unprognostic (9.60e-2)" "unprognostic (5.39e-2)" "unprognostic (1.82e-1)" ENSG00000206549 ENSG00000206549 "Novel protein identical to PRSS50" 3 46712115-46812574 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "pituitary gland: 4.1;skeletal muscle: 4.5;thyroid gland: 5.1" "Cell type enriched" "Detected in some" 4 "Myonuclei: 25.6" "Cancer enhanced" "Detected in single" "Thyroid Carcinoma (TCGA): 1.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA040768 Supported NA NA "Cluster 21: Testis - Mixed function" "Cluster 44: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 55: Myocytes - Oxidative muscle function" "HPA040768: " "unprognostic (2.76e-2)" "unprognostic (1.74e-1)" ENSG00000225528 ENSG00000225528 "Novel protein similar to translation machinery associated 7 homolog (S. cerevisiae) TMA7" 22 39960397-39964905 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Tissue enhanced" "Detected in some" "bone marrow: 1.1;lymphoid tissue: 3.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Adipose visceral - T-cells, Thyroid gland - T-cells" HPA047397 Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Nuclear bodies" Yes NA "Cluster 33: Non-specific - ATP binding" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 26: Keratinocytes - Keratinization" "Nucleoli, Nucleoli rim" "Nucleoplasm, Nuclear bodies" "HPA047397: " ENSG00000226690 ENSG00000226690 "Novel protein" 7 12469621-12542222 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 7 "fallopian tube: 4.1" "Cell type enhanced" "Detected in some" "Early spermatids: 62.1;Endometrial ciliated cells: 126.0;Ependymal cells: 294.7;Epididymal efferent duct ciliated cells: 113.7;Fallopian tube ciliated cells: 125.0;Late primary spermatocytes: 78.5;Late spermatids: 250.1;Respiratory ciliated cells: 164.4" "Cell type enriched" "Detected in some" 69 "ependymal cell: 352.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Region enhanced" "Detected in many" "midbrain: 8.5" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 34: Ciliated cells - Cilia assembly & function" "unprognostic (2.45e-2)" ENSG00000230707 ENSG00000230707 "Novel protein (LOC389895)" X 140091678-140092911 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "adrenal gland: 7.4;brain: 7.1;testis: 2.3" "Cell type enhanced" "Detected in some" "Adrenal cortex cells: 4.3;Differentiating spermatogonia: 2.0;Early primary spermatocytes: 5.8;Fallopian tube ciliated cells: 1.7;Oocytes: 4.6;Retinal bipolar cells: 1.1;Undifferentiated spermatogonia: 1.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 1.2;Testicular Germ Cell Tumor (TCGA): 1.2;Uterine Corpus Endometrial Carcinoma (TCGA): 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Bone cancer: 1.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041568 Uncertain NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 51: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 18: Adrenal cortex cells - Steroidogensis" 2 "HPA041568: " "unprognostic (1.35e-1)" "unprognostic (2.17e-1)" "unprognostic (2.25e-1)" "unprognostic (2.23e-1)" ENSG00000233757 ENSG00000233757 "Novel C2H2 type zinc finger protein" 2 95207521-95259774 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Early spermatids: 35.7;Late spermatids: 33.8;Oligodendrocyte progenitor cells: 41.0;Oligodendrocytes: 47.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" NA NA "Cluster 61: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 109: Neurons - Neuronal signaling" "unprognostic (1.99e-1)" "unprognostic (2.56e-3)" "unprognostic (2.66e-1)" "unprognostic (8.03e-2)" "unprognostic (1.55e-3)" "unprognostic (8.00e-3)" "unprognostic (3.16e-1)" ENSG00000235007 ENSG00000235007 "Novel protein" 9 129139413-129260575 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "Astrocytes: 13.5;Cardiomyocytes: 21.1;Epicardial cells: 13.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD8 T-cell: 2.1" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in single" "testis cancer: 1.7" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 37: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "unprognostic (1.78e-2)" "unprognostic (1.67e-1)" "unprognostic (7.89e-3)" "unprognostic (3.10e-1)" "unprognostic (1.88e-1)" ENSG00000236543 ENSG00000236543 "Novel beta-lactoglobulin-like protein" 9 135604345-135619893 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 42 "skin 1: 10.8" "Cell type enhanced" "Detected in some" "Endometrial glandular cells: 1.6;Epididymal efferent duct ciliated cells: 1.3" "Cell type enhanced" "Detected in single" "Bergmann glia: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 37: Skin - Keratinization" "Cluster 34: Testis cancer - Unknown function" "Cluster 51: Secretory epithelial cells - Mixed function" ENSG00000237378 ENSG00000237378 "Novel keratin-associated protein" 13 63746741-63751080 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "breast: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 105: Non-specific - Mixed function" ENSG00000239395 ENSG00000239395 "Novel protein" 1 247711813-247723764 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 14 "testis: 1.3" "Cell type enhanced" "Detected in some" "Adipocytes: 4.7;Early spermatids: 4.4;Late primary spermatocytes: 2.8;Late spermatids: 6.9;Mast cells: 1.0;Myosatellite cells: 1.0;Thymocytes: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 72: Neuronal - Signal transduction" "Cluster 89: Adipocytes - Lipid metabolism" ENSG00000241489 ENSG00000241489 "Novel protein" X 149477104-149540926 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Platelets: 1.4;Salivary ionocytes: 1.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 15.9" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 22: Epididymis - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 47: Platelets - Hemostasis" "unprognostic (1.63e-1)" "unprognostic (4.26e-1)" "unprognostic (9.32e-3)" "unprognostic (2.60e-2)" "unprognostic (1.41e-1)" "unprognostic (2.12e-1)" "unprognostic (2.05e-1)" "unprognostic (2.96e-2)" "potential prognostic unfavorable (3.73e-4)" "potential prognostic unfavorable (3.29e-5)" "unprognostic (1.72e-1)" "unprognostic (3.09e-1)" "unprognostic (3.83e-2)" "unprognostic (2.22e-2)" "unprognostic (3.52e-1)" "unprognostic (7.50e-2)" "unprognostic (6.27e-3)" "unprognostic (1.53e-1)" "unprognostic (1.39e-1)" "unprognostic (2.72e-3)" "unprognostic (1.58e-1)" "unprognostic (1.00e-2)" "unprognostic (7.86e-3)" "unprognostic (2.95e-3)" "unprognostic (7.63e-3)" "unprognostic (2.93e-2)" "unprognostic (7.41e-2)" "unprognostic (3.22e-1)" "unprognostic (7.67e-3)" ENSG00000241690 ENSG00000241690 "Novel protein" 20 2814968-2818066 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 16 "testis: 6.1" "Cell type enriched" "Detected in some" 6 "Late spermatids: 33.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA077873 Approved "Vesicles,Plasma membrane" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" "Plasma membrane" Vesicles "HPA077873: " ENSG00000244255 ENSG00000244255 "Novel complement component 2 (C2) and complement factor B (CFB) protein" 6 31927698-31952048 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "liver: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA000951, HPA001817, HPA001832" Approved Approved "Endoplasmic reticulum,Vesicles,Cell Junctions" NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Endoplasmic reticulum, Vesicles" "Cell Junctions" "HPA000951: , HPA001817: , HPA001832: " "unprognostic (1.72e-1)" "unprognostic (9.20e-2)" ENSG00000248235 ENSG00000248235 "Novel protein" 8 22589274-22602084 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 2.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 4.7" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 3.3" HPA024667 Uncertain NA NA "Cluster 66: Lymphoid tissue - Immune response" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 82: Dendritic cells - Antigen presentation" "HPA024667: " "unprognostic (1.73e-1)" "unprognostic (2.26e-1)" "unprognostic (5.08e-2)" "unprognostic (2.08e-3)" "unprognostic (1.67e-2)" "unprognostic (1.94e-1)" "unprognostic (1.97e-1)" "unprognostic (2.15e-1)" "unprognostic (5.61e-1)" ENSG00000248751 ENSG00000248751 "Novel protein" 22 30285238-30299482 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Cone photoreceptor cells: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA073183 Uncertain NA NA "Cluster 44: Connective tissue cells - ECM organization" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "HPA073183: " ENSG00000248993 ENSG00000248993 "Novel protein" 6 32937364-32953122 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Uterine Corpus Endometrial Carcinoma (TCGA): 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA012298 Uncertain NA NA "Cluster 46: Lymphoma - Humoral immune response" "Cluster 105: Non-specific - Mixed function" "HPA012298: " "unprognostic (2.36e-1)" ENSG00000249141 ENSG00000249141 "Novel protein" 6 166858094-166956124 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "pancreas: 3.3" "Cell type enhanced" "Detected in many" "B-cells: 12.6;cDC: 12.1;Endometrial glandular cells: 13.3;Endometrial luminal cells: 14.7;Macrophages: 13.4;Microglia: 34.3;monocytes: 12.2;Neutrophils: 33.9;Thymocytes: 17.8" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 41.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in some" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 60: Stomach - Digestion" "Cluster 33: Neurons - Mixed function" "Cluster 61: BICR 18 - Protein kinases" "Cluster 24: Neutrophils - Innate immunity signal integration" "unprognostic (1.40e-2)" "unprognostic (8.50e-2)" "unprognostic (3.77e-2)" "unprognostic (1.19e-1)" "unprognostic (1.16e-1)" "unprognostic (1.18e-2)" "unprognostic (2.85e-1)" "potential prognostic unfavorable (3.17e-4)" "unprognostic (4.91e-3)" "unprognostic (3.78e-2)" "unprognostic (1.19e-1)" "unprognostic (6.40e-2)" "unprognostic (8.39e-3)" "unprognostic (1.15e-1)" "unprognostic (8.00e-2)" "unprognostic (1.00e-1)" "unprognostic (3.31e-1)" "unprognostic (2.99e-1)" ENSG00000249209 ENSG00000249209 "Novel protein similar to ATP synthase delta (OSCP) subunit domain" 21 33584687-33931607 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in single" "Group enriched" "Detected in many" 4 "Adipocytes: 1994.6;Epicardial cells: 1798.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Lineage enriched" "Detected in all" 6 "T-cells: 12.8" "Low cancer specificity" "Detected in many" HPA039558 Uncertain NA NA "Cluster 11: T-cells - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 56: Non-specific - Sensory perception" "Cluster 89: Adipocytes - Lipid metabolism" "HPA039558: " "unprognostic (1.41e-1)" "unprognostic (2.00e-1)" "unprognostic (2.21e-1)" "potential prognostic unfavorable (7.35e-4)" "unprognostic (1.46e-2)" "unprognostic (4.67e-3)" "unprognostic (4.12e-1)" "unprognostic (3.39e-2)" "unprognostic (3.13e-1)" "unprognostic (1.44e-1)" "unprognostic (1.14e-1)" "potential prognostic favorable (5.71e-4)" "unprognostic (2.19e-1)" "unprognostic (3.44e-2)" "unprognostic (1.96e-1)" "unprognostic (7.74e-2)" ENSG00000249240 ENSG00000249240 "Novel protein" 15 64841883-64930920 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 5.5" "Cell type enhanced" "Detected in many" "Astrocytes: 60.8;Bergmann glia: 69.5;cDC: 69.2;Hofbauer cells: 154.7;Kupffer cells: 65.6;Macrophages: 97.4;monocytes: 85.2;Müller glia: 127.3;Neutrophils: 254.7" "Cell type enhanced" "Detected in many" "astrocyte: 70.1;Bergmann glia: 71.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 55: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 29: Neutrophils - Innate immune cellular maintenance" "unprognostic (4.73e-2)" "unprognostic (1.29e-2)" "unprognostic (5.37e-2)" "unprognostic (1.37e-2)" "unprognostic (1.92e-1)" "unprognostic (4.35e-1)" ENSG00000249319 ENSG00000249319 "Novel protein" 7 66087761-66152277 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hepatocytes: 44.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 1: Neurons - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 65: Non-specific - Cell growth & division" "unprognostic (5.17e-2)" "unprognostic (3.05e-1)" "unprognostic (2.39e-2)" "unprognostic (4.13e-2)" "unprognostic (4.20e-1)" "unprognostic (3.51e-1)" "unprognostic (2.70e-1)" "unprognostic (1.54e-1)" "unprognostic (4.33e-2)" "unprognostic (4.11e-3)" "unprognostic (7.05e-2)" "unprognostic (1.96e-1)" "unprognostic (2.54e-2)" "unprognostic (2.69e-1)" "unprognostic (1.25e-1)" "unprognostic (3.37e-1)" ENSG00000249590 ENSG00000249590 "Novel SEC14-like 2 (S. cerevisiae) (SEC14L2) and mitochondrial protein 18 kDa (MTP18) protein" 22 30409255-30428990 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "liver: 1.8;retina: 6.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 12.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 1.2;testis cancer: 1.2" NA NA "Cluster 42: Retina - Visual perception" "Cluster 21: Non-specific - Metabolism" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (6.88e-2)" "potential prognostic unfavorable (7.90e-4)" "unprognostic (1.35e-1)" "unprognostic (3.35e-1)" "unprognostic (1.32e-2)" "unprognostic (1.72e-1)" "unprognostic (7.18e-2)" "unprognostic (2.28e-2)" "unprognostic (9.44e-2)" "unprognostic (5.25e-1)" "unprognostic (6.02e-1)" "unprognostic (6.63e-1)" ENSG00000249624 ENSG00000249624 "Novel protein" 21 33229892-33297160 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Epicardial cells: 4.5;Kupffer cells: 2.0;Macrophages: 1.3;monocytes: 1.8;Neutrophils: 3.4;pDCs: 2.1;Platelets: 1.4;Retinal horizontal cells: 2.0" "Cell type enhanced" "Detected in single" "endothelial cell: 1.5" "Cancer enhanced" "Detected in single" "Stomach Adenocarcinoma (TCGA): 1.3" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Myeloma: 2.3" HPA047550 Uncertain NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "HPA047550: " "unprognostic (2.14e-1)" "unprognostic (1.62e-2)" "unprognostic (5.17e-2)" "unprognostic (1.19e-1)" ENSG00000249773 ENSG00000249773 "Novel zinc finger protein 713 (ZNF713) and mitochondrial ribosomal protein S17 (MRPS17) protein" 7 55887277-55955239 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "testis: 2.6" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 8.9;Fallopian tube ciliated cells: 7.8;Lactotrophs: 7.6;Respiratory ciliated cells: 9.0;Somatotrophs: 7.6;Thyrotrophs: 13.4" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 3.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" HPA047159 Uncertain NA NA "Cluster 67: Testis - Mixed function" "Cluster 27: Non-specific - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 107: Ciliated cells - Cilia assembly & function" "HPA047159: " "unprognostic (2.29e-1)" "unprognostic (3.57e-3)" "unprognostic (1.30e-1)" "unprognostic (1.03e-1)" "unprognostic (1.98e-1)" "unprognostic (2.79e-2)" "unprognostic (5.44e-1)" ENSG00000249967 ENSG00000249967 "Novel protein" 10 97584374-97673910 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "tongue: 1.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 96.2;Cholangiocytes: 21.0;Endometrial glandular cells: 19.6;Endometrial luminal cells: 27.4;Epicardial cells: 31.8;Late spermatids: 31.3;Proximal tubule cells: 28.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA076857 Uncertain "Plasma membrane" NA NA "Cluster 63: Non-specific - Basic cellular processes" "Cluster 61: BICR 18 - Protein kinases" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" "Plasma membrane" "HPA076857: " ENSG00000250264 ENSG00000250264 "Novel protein, TAP2-HLA-DOB readthrough" 6 32813767-32838822 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 6.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" HPA001312 Approved Approved "Nuclear speckles,Endoplasmic reticulum" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 27: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 105: Non-specific - Mixed function" "Nuclear speckles, Endoplasmic reticulum" "HPA001312: " "unprognostic (4.53e-2)" "unprognostic (5.01e-3)" "unprognostic (1.17e-1)" "unprognostic (2.04e-2)" "unprognostic (1.12e-3)" "unprognostic (2.37e-1)" "unprognostic (3.79e-2)" "unprognostic (2.01e-2)" "potential prognostic favorable (3.15e-6)" "unprognostic (3.50e-2)" "unprognostic (2.02e-1)" "unprognostic (2.29e-1)" "unprognostic (2.06e-1)" "unprognostic (1.95e-1)" "unprognostic (8.24e-2)" "unprognostic (1.92e-1)" "unprognostic (8.08e-2)" "unprognostic (4.08e-2)" "unprognostic (7.53e-2)" "unprognostic (4.61e-1)" "unprognostic (4.40e-2)" "unprognostic (2.43e-2)" "unprognostic (4.48e-2)" "unprognostic (1.09e-1)" "unprognostic (1.47e-1)" "unprognostic (1.23e-2)" "unprognostic (3.48e-1)" "unprognostic (3.01e-1)" ENSG00000250349 ENSG00000250349 "Novel proline rich Gla (G-carboxyglutamic acid) 1 (PRRG1) and tetraspanin 7 (TSPAN7) protein" X 37349330-38687674 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "skeletal muscle: 4.4" "Group enriched" "Detected in some" 4 "Distal convoluted tubule cells: 25.1;Loop of henle epithelial cells: 45.5;Papillary tip epithelial cells: 23.2;Proximal tubule cells: 30.4;Renal collecting duct intercalated cells: 55.5;Renal collecting duct principal cells: 45.2;Renal connecting tubule cells: 27.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA003140 Uncertain NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 30: White matter - Myelination" "Cluster 59: Leukemia - T-cell receptor" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" "HPA003140: " "unprognostic (6.17e-3)" "unprognostic (2.00e-1)" ENSG00000250424 ENSG00000250424 "Novel protein, MINDY4 and AQP1 readthrough" 7 30852273-30923812 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "blood vessel: 1.2" "Cell type enhanced" "Detected in some" "Enterocytes: 2.9;Epicardial cells: 6.8;Erythrocyte progenitors: 1.9;Fibro-adipogenic progenitors: 3.0;Mesothelial cells: 3.9;Renal collecting duct principal cells: 1.6;Renal connecting tubule cells: 2.9;Thyrotrophs: 1.7" "Cancer enhanced" "Detected in single" "Uterine Corpus Endometrial Carcinoma (TCGA): 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA019206, HPA030130" Approved Approved "Plasma membrane" NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 70: DU4475 - Unknown function" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" "Plasma membrane" "HPA019206: , HPA030130: " "unprognostic (4.60e-1)" ENSG00000250644 ENSG00000250644 "Novel protein" 11 1734821-1763954 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "adrenal gland: 198.1;blood vessel: 79.3" "Cell type enhanced" "Detected in some" "Epicardial cells: 2.3;Gastric progenitor cells: 1.3;Macrophages: 1.2;Mast cells: 3.6;monocytes: 1.8;Neutrophils: 1.3;Prostatic hillock cells: 1.9;Renal connecting tubule cells: 1.7;Respiratory basal cells: 1.2;Retinal pigment epithelial cells: 4.3;Thymic myoid cells: 1.4;Urothelial cells: 1.2" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 1.1;choroid plexus epithelial cell: 1.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Kidney cancer: 71.5" HPA003001 Uncertain NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 58: Mast cells - Allergic inflammatory responses" "HPA003001: " "unprognostic (6.00e-2)" "unprognostic (5.55e-3)" "unprognostic (2.26e-1)" "unprognostic (1.94e-3)" "unprognostic (1.84e-2)" "potential prognostic unfavorable (9.93e-5)" "unprognostic (3.06e-1)" "unprognostic (2.39e-1)" "unprognostic (7.28e-2)" "unprognostic (1.88e-3)" "unprognostic (1.66e-1)" "unprognostic (5.73e-2)" "unprognostic (3.09e-1)" "unprognostic (1.69e-1)" "unprognostic (2.27e-2)" "unprognostic (6.38e-2)" "unprognostic (1.60e-1)" "unprognostic (2.52e-1)" "unprognostic (3.01e-2)" "unprognostic (8.06e-2)" "unprognostic (2.01e-1)" "unprognostic (1.78e-3)" "unprognostic (6.74e-3)" "unprognostic (2.51e-1)" "unprognostic (1.49e-2)" "unprognostic (3.85e-1)" "unprognostic (1.73e-3)" "unprognostic (4.00e-1)" ENSG00000250803 ENSG00000250803 "Zinc finger protein 474-like (LOC100505841)" 5 122129622-122182658 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 93 "testis: 185.2" "Group enriched" "Detected in some" 6 "Early spermatids: 120.6;Late spermatids: 326.1" "Cell type enriched" "Detected in some" 6 "ependymal cell: 40.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Late spermatids" "Not detected" "Not detected" "Region enhanced" "Detected in many" "midbrain: 14.3" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 46: Brainstem - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" "unprognostic (6.99e-2)" ENSG00000251012 ENSG00000251012 "Novel chromosome 3 open reading frame 30 (C3orf30) and uroplakin 1B (UPK1B)" 3 119147375-119187807 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Early spermatids: 103.5;Late primary spermatocytes: 88.5;Late spermatids: 26.9" "Low cell type specificity" "Detected in single" "Not detected" "Not detected" "Region enhanced" "Detected in single" "white matter: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" ENSG00000251184 ENSG00000251184 "Novel protein" 9 128941478-128957021 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "retina: 2.3;skeletal muscle: 1.4" "Cell type enhanced" "Detected in some" "Adipocytes: 7.0;Bergmann glia: 4.6;Breast myoepithelial cells: 5.2;Cardiomyocytes: 13.5;Epicardial cells: 11.4;Rod photoreceptor cells: 4.5" "Cell type enhanced" "Detected in some" "astrocyte: 3.5;Bergmann glia: 2.3" "Cancer enhanced" "Detected in single" "Uterine Corpus Endometrial Carcinoma (TCGA): 1.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" ENSG00000251357 ENSG00000251357 "Novel protein" 22 23862188-23895223 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Astrocytes: 4.1;Bergmann glia: 2.6;Brain excitatory neurons: 3.7;Brain inhibitory neurons: 3.8;Choroid plexus epithelial cells: 3.3;Distal convoluted tubule cells: 3.0;Ependymal cells: 3.1;Loop of henle epithelial cells: 4.3;Oligodendrocyte progenitor cells: 2.1;Oligodendrocytes: 2.7;Other brain neurons: 3.1;Papillary tip epithelial cells: 1.6;Podocytes: 2.1;Proximal tubule cells: 6.2;Renal collecting duct intercalated cells: 2.6;Renal collecting duct principal cells: 2.7;Renal connecting tubule cells: 4.5" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA042960 Uncertain NA NA "Cluster 24: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 88: Proximal tubular cells - Transmembrane transport" "HPA042960: " ENSG00000251537 ENSG00000251537 "Novel tripartite motif-containing 16 (TRIM16) and CMT1A duplicated region transcript 1 (CDRT1) protein" 17 15571491-15651653 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 10.6;Endometrial luminal cells: 7.2;Esophageal apical cells: 11.7;Foveolar cells: 8.5;Ocular epithelial cells: 16.1;Paneth cells: 7.7;Salivary duct cells: 8.6;Suprabasal keratinocytes: 8.1;Urothelial cells: 18.4" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA023623, HPA066431" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 42: Choroid plexus - Mitochondria" "Cluster 7: Liver cancer - Metabolism" "Cluster 100: Stratified epithelial cells - Barrier functions" Cytosol "Plasma membrane" "HPA023623: , HPA066431: " ENSG00000251569 ENSG00000251569 "Novel protein" 2 169479480-169525922 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "retina: 16.6;testis: 8.0" "Cell type enhanced" "Detected in some" "Adrenal cortex cells: 2.2;Gastric chief cells: 2.2;Gonadotrophs: 2.0;Myonuclei: 5.4;Parietal cells: 5.3;Respiratory ciliated cells: 1.8;Thymic myoid cells: 9.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "skin cancer: 1.2" HPA046125 Uncertain Approved "Primary cilium,Basal body,Cytosol,Acrosome,Perinuclear theca" NA NA "Cluster 42: Retina - Visual perception" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 46: Skeletal myocytes - Muscle structure & formation" "Basal body, Cytosol, Acrosome" "Primary cilium, Perinuclear theca" "HPA046125: " "unprognostic (1.19e-1)" ENSG00000254692 ENSG00000254692 "Novel protein" 14 24189157-24213473 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Group enriched" "Detected in some" 10 "Distal convoluted tubule cells: 13.6;Loop of henle epithelial cells: 17.5;Papillary tip epithelial cells: 16.6;Podocytes: 18.6;Proximal tubule cells: 18.7;Renal collecting duct intercalated cells: 14.9;Renal collecting duct principal cells: 15.0;Renal connecting tubule cells: 14.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" HPA059249 Approved Approved "Golgi apparatus" NA NA "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 105: Non-specific - Mixed function" "Golgi apparatus" "HPA059249: " "unprognostic (3.21e-1)" "unprognostic (7.13e-3)" "unprognostic (2.60e-1)" "unprognostic (5.47e-2)" "unprognostic (4.59e-3)" "unprognostic (2.05e-1)" "unprognostic (3.87e-1)" "unprognostic (2.47e-1)" "unprognostic (1.36e-1)" "unprognostic (9.52e-3)" "unprognostic (6.04e-2)" "unprognostic (5.70e-2)" "unprognostic (1.63e-1)" ENSG00000254706 ENSG00000254706 "Novel protein" 1 162365407-162383531 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 53.2;Cone photoreceptor cells: 31.1;Thyrotrophs: 12.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "HPA052251, HPA074060" Uncertain Approved Nucleoplasm NA NA "Cluster 60: Stomach - Digestion" "Cluster 44: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 79: Photoreceptor cells - Phototransduction" Nucleoplasm "HPA052251: , HPA074060: " "unprognostic (1.49e-2)" "unprognostic (4.47e-3)" "unprognostic (8.26e-2)" "unprognostic (1.19e-1)" "unprognostic (3.64e-2)" "unprognostic (3.05e-3)" "unprognostic (1.05e-1)" "unprognostic (1.18e-2)" "unprognostic (7.06e-2)" "unprognostic (1.85e-1)" "unprognostic (1.65e-1)" "unprognostic (6.75e-2)" "unprognostic (4.69e-1)" "unprognostic (4.44e-2)" "unprognostic (2.67e-2)" "unprognostic (4.71e-1)" "unprognostic (1.41e-1)" "unprognostic (1.65e-1)" "unprognostic (1.76e-2)" "unprognostic (1.61e-1)" "unprognostic (1.09e-1)" "unprognostic (3.53e-2)" ENSG00000254979 ENSG00000254979 "Novel protein" 11 57387365-57424059 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 12.5;liver: 6.8;placenta: 6.6" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 4.3;Basal keratinocytes: 3.2;Erythrocyte progenitors: 5.6;Fibro-adipogenic progenitors: 6.7;Hepatocytes: 3.2;Macrophages: 3.3;Mast cells: 3.7;monocytes: 8.0;Neutrophil progenitors: 3.4;Neutrophils: 7.0;Respiratory deuterosomal cells: 3.1;Salivary basal cells: 6.3;Transitional alveolar cells: 3.4" "Cell type enhanced" "Detected in some" "pericyte: 1.2;vascular associated smooth muscle cell: 1.3" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 5.4" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 9 "basophil: 3.6" "Lineage enriched" "Detected in single" 9 "granulocytes: 3.6" "Cancer enriched" "Detected in some" 5 "Leukemia: 13.0" HPA038515 Supported NA NA "Cluster 15: Bone marrow - Innate immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" "HPA038515: " "unprognostic (3.56e-1)" "unprognostic (1.43e-2)" "unprognostic (1.40e-1)" "unprognostic (4.82e-2)" "unprognostic (9.05e-2)" "unprognostic (2.94e-1)" "unprognostic (3.55e-2)" "unprognostic (2.69e-1)" "unprognostic (6.29e-2)" "unprognostic (3.51e-2)" ENSG00000255432 ENSG00000255432 "Novel protein" 11 62649694-62665178 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "skeletal muscle: 1.0" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 6.2;Paneth cells: 7.7;Retinal ganglion cells: 11.6;Rod photoreceptor cells: 4.7;Thymocytes: 4.2" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 3.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 32: Basophils - Transcription" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 61: BICR 18 - Protein kinases" "Cluster 79: Photoreceptor cells - Phototransduction" 11 ENSG00000255439 ENSG00000255439 "Novel protein, VKORC1 and PRSS53 readthrough" 16 31083439-31094956 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Leydig cells: 7.5;Retinal amacrine cells: 6.2;Retinal bipolar cells: 5.9;Rod photoreceptor cells: 5.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" HPA042720 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 2: Non-specific - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 94: Gonadal somatic cells - Mixed function" "Endoplasmic reticulum" "HPA042720: " "unprognostic (6.08e-2)" ENSG00000255639 ENSG00000255639 "Novel protein" 12 4649101-4774184 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 21.7;tongue: 17.3" "Cell type enhanced" "Detected in many" "Early spermatids: 98.2;Late primary spermatocytes: 22.6;Oligodendrocyte progenitor cells: 28.0;Retinal bipolar cells: 24.0;Undifferentiated spermatogonia: 56.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA012638, HPA042268, HPA073212" Supported Approved Nucleoplasm,Mitochondria No NA "Cluster 33: Non-specific - ATP binding" "Cluster 76: Non-specific - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" Mitochondria Nucleoplasm "HPA012638: , HPA042268: , HPA073212: " "unprognostic (2.27e-1)" "unprognostic (2.29e-1)" "unprognostic (4.63e-2)" "unprognostic (4.67e-2)" "unprognostic (3.21e-2)" "unprognostic (1.61e-1)" "unprognostic (7.27e-3)" "unprognostic (8.09e-2)" "potential prognostic favorable (2.18e-7)" "unprognostic (2.52e-1)" "unprognostic (7.05e-3)" "potential prognostic unfavorable (4.39e-4)" "unprognostic (2.26e-1)" "unprognostic (2.23e-1)" "unprognostic (1.92e-1)" "unprognostic (1.36e-2)" "unprognostic (1.17e-2)" "unprognostic (8.51e-2)" "unprognostic (2.24e-2)" "unprognostic (1.91e-2)" "unprognostic (2.62e-1)" "unprognostic (9.49e-2)" "unprognostic (1.56e-1)" "unprognostic (1.40e-1)" ENSG00000255641 ENSG00000255641 "Novel protein" 12 10412312-10436001 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 6.4;lymphoid tissue: 4.4" "Group enriched" "Detected in some" 9 "NK-cells: 28.1;T-cells: 8.5" "Cancer enriched" "Detected in some" 4 "Glioblastoma Multiforme (TCGA): 4.8" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 6 "NK-cell: 135.0" "Lineage enriched" "Detected in many" 6 "NK-cells: 135.0" "Cancer enhanced" "Detected in some" "testis cancer: 3.0;thyroid cancer: 3.7" HPA062570 Uncertain NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" "HPA062570: " "unprognostic (2.01e-3)" "unprognostic (3.38e-2)" "potential prognostic favorable (4.44e-4)" ENSG00000255730 ENSG00000255730 "Novel protein" 19 41350853-41425001 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 25.3;Epicardial cells: 27.3;Megakaryocytes: 12.4;Neutrophils: 9.4;Platelets: 33.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "neutrophil: 2.4" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" HPA036640 Approved NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" "HPA036640: " "unprognostic (4.26e-1)" "unprognostic (1.93e-2)" "unprognostic (4.88e-1)" "unprognostic (2.93e-1)" "unprognostic (4.40e-1)" "unprognostic (2.63e-1)" ENSG00000255835 ENSG00000255835 "Novel protein" 1 225886696-225924278 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 10.4;Lactotrophs: 9.4;Retinal bipolar cells: 10.8;Rod photoreceptor cells: 14.8;Thyrotrophs: 14.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA065738, HPA067935" Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 14: Neurons - Synaptic function" "Cluster 72: Neuronal - Signal transduction" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" Nucleoplasm "Vesicles, Cytosol" "HPA065738: , HPA067935: " ENSG00000256349 ENSG00000256349 "Novel protein" 11 66509079-66533613 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "retina: 2.1" "Cell type enriched" "Detected in some" 4 "Rod photoreceptor cells: 11.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA058283 Uncertain Approved Midbody Yes NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 55: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 79: Photoreceptor cells - Phototransduction" Midbody "HPA058283: " "unprognostic (9.60e-3)" "unprognostic (6.05e-1)" "unprognostic (8.15e-3)" "unprognostic (4.54e-1)" "unprognostic (6.38e-3)" "unprognostic (9.03e-2)" "unprognostic (1.12e-1)" "unprognostic (3.55e-1)" "unprognostic (8.18e-2)" "unprognostic (4.40e-1)" "unprognostic (7.16e-2)" ENSG00000256500 ENSG00000256500 "Novel protein" 14 103562962-103685924 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 21.3;tongue: 15.3" "Group enriched" "Detected in some" 8 "Early spermatids: 2.0;Late spermatids: 6.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "HPA044617, HPA052450" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol,Acrosome,Equatorial segment" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 1: Neurons - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" "Plasma membrane, Acrosome, Equatorial segment" "Nucleoplasm, Cytosol" "HPA044617: , HPA052450: " "unprognostic (1.25e-1)" "unprognostic (2.29e-1)" "unprognostic (1.01e-1)" "unprognostic (4.39e-3)" "unprognostic (3.55e-1)" "unprognostic (3.69e-3)" "unprognostic (1.93e-1)" "potential prognostic favorable (2.10e-5)" "unprognostic (3.94e-2)" "potential prognostic unfavorable (2.12e-5)" "unprognostic (1.31e-2)" "unprognostic (1.76e-1)" "unprognostic (3.48e-1)" "unprognostic (1.63e-1)" "unprognostic (1.28e-1)" "unprognostic (8.15e-3)" "unprognostic (8.17e-3)" "unprognostic (3.39e-2)" "unprognostic (1.80e-1)" "unprognostic (1.16e-1)" "unprognostic (7.00e-2)" "unprognostic (1.22e-1)" "unprognostic (2.26e-1)" "unprognostic (1.18e-1)" "unprognostic (2.48e-1)" ENSG00000256514 ENSG00000256514 "Novel protein" 11 67351572-67373584 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 8.3;Endometrial glandular cells: 6.3;Endometrial luminal cells: 8.1;Epicardial cells: 15.9;Salivary myoepithelial cells: 7.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA078008 Approved "Centriolar satellite" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 70: Non-specific - Protein processing" "Cluster 27: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" "Centriolar satellite" "HPA078008: " "unprognostic (4.55e-2)" "unprognostic (9.10e-2)" "unprognostic (9.98e-2)" "unprognostic (3.89e-2)" "unprognostic (8.18e-3)" "potential prognostic unfavorable (9.12e-4)" "unprognostic (7.64e-2)" "unprognostic (9.95e-2)" "validated prognostic unfavorable (6.40e-6)" "validated prognostic unfavorable (2.30e-5)" "unprognostic (2.62e-1)" "unprognostic (1.50e-1)" "unprognostic (2.03e-2)" "potential prognostic unfavorable (8.97e-5)" "unprognostic (3.40e-1)" "unprognostic (3.05e-3)" "unprognostic (3.03e-1)" "unprognostic (1.55e-1)" "unprognostic (1.27e-2)" "unprognostic (4.56e-2)" "unprognostic (1.34e-1)" "unprognostic (3.78e-2)" "unprognostic (6.08e-2)" "unprognostic (2.78e-1)" "unprognostic (1.76e-1)" "unprognostic (1.62e-1)" "unprognostic (2.53e-1)" ENSG00000256591 ENSG00000256591 "Novel transcript" 11 61429220-61485822 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Myonuclei: 142.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA039732 Approved NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 61: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 55: Myocytes - Oxidative muscle function" "HPA039732: " "unprognostic (1.68e-2)" "unprognostic (2.88e-2)" "unprognostic (6.66e-2)" "unprognostic (4.83e-2)" "unprognostic (8.13e-2)" "unprognostic (1.78e-2)" "unprognostic (1.38e-2)" "unprognostic (3.75e-1)" "unprognostic (4.22e-2)" "unprognostic (2.51e-1)" "unprognostic (2.06e-1)" "unprognostic (2.02e-1)" "unprognostic (9.41e-2)" "unprognostic (4.18e-2)" "unprognostic (2.12e-1)" "unprognostic (2.52e-1)" "unprognostic (1.01e-2)" "unprognostic (2.26e-1)" "unprognostic (2.48e-2)" "unprognostic (1.36e-1)" "unprognostic (1.88e-2)" "unprognostic (1.49e-1)" "unprognostic (1.40e-1)" "unprognostic (1.34e-2)" "unprognostic (2.68e-1)" "unprognostic (1.04e-1)" "unprognostic (5.87e-1)" ENSG00000256646 ENSG00000256646 "Novel PSMA2 and C7orf25 readthrough" 7 42909273-42932214 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Epicardial cells: 4.5;Hepatic stellate cells: 6.5;Oocytes: 4.6;Sertoli cells: 4.5" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in single" "Uterine Corpus Endometrial Carcinoma (TCGA): 1.0" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" HPA008188 Uncertain NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 67: Non-specific - Unknown function" "Cluster 37: Neutrophil progenitors - Granulopoiesis" "HPA008188: " "unprognostic (3.18e-2)" "unprognostic (6.64e-2)" "unprognostic (7.58e-2)" ENSG00000256825 ENSG00000256825 "Novel protein" 12 133130984-133202369 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 10.6;Early primary spermatocytes: 5.9;Late primary spermatocytes: 7.3;Pancreatic islet cells: 9.0;pDCs: 8.4;Thymocytes: 14.4;Undifferentiated spermatogonia: 8.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" ENSG00000257184 ENSG00000257184 "HOXA10-HOXA9 readthrough" 7 27163535-27180013 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "Uterine Corpus Endometrial Carcinoma (TCGA): 2.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 15: Kidney cancer - Membrane components" "Cluster 108: Fibroblasts - ECM organization" "unprognostic (3.90e-1)" ENSG00000257390 ENSG00000257390 "Novel protein" 12 55757275-55827546 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 9 "testis: 8.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 17.2;Epicardial cells: 20.5;Late spermatids: 6.3;Thymocytes: 6.8" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in some" "HPA017653, HPA030902, HPA030903" Uncertain Approved "Nuclear speckles,Cytoplasmic bodies" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 47: Testis - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "Nuclear speckles" "Cytoplasmic bodies" "HPA017653: , HPA030902: , HPA030903: " "unprognostic (2.99e-2)" "unprognostic (1.21e-1)" "unprognostic (1.27e-1)" "unprognostic (2.45e-2)" "unprognostic (7.16e-2)" "unprognostic (5.00e-3)" "unprognostic (6.92e-3)" "unprognostic (8.98e-3)" "unprognostic (7.73e-2)" "unprognostic (1.94e-2)" "unprognostic (1.89e-1)" "unprognostic (1.43e-1)" "unprognostic (3.42e-1)" "unprognostic (1.08e-1)" "unprognostic (4.51e-2)" "unprognostic (3.58e-1)" "unprognostic (3.54e-1)" "unprognostic (2.72e-1)" ENSG00000257411 ENSG00000257411 "Novel protein" 12 56101331-56109289 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 31.7;Epicardial cells: 11.4;Suprabasal keratinocytes: 5.5" "Group enriched" "Detected in some" 5 "Ovary Serous Cystadenocarcinoma (TCGA): 12.9;Stomach Adenocarcinoma (TCGA): 17.1" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 22 "testis cancer: 37.7" NA NA "Cluster 61: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" "unprognostic (1.72e-3)" "unprognostic (1.33e-1)" "unprognostic (1.14e-2)" "unprognostic (6.94e-3)" "unprognostic (4.82e-2)" "unprognostic (4.44e-2)" "unprognostic (1.96e-1)" "unprognostic (9.14e-2)" ENSG00000257767 ENSG00000257767 "Novel protein" 12 111753890-111791418 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "adipose tissue: 60.1;skeletal muscle: 35.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 6.2;Tuft cells: 11.5" "Cancer enhanced" "Detected in many" "Stomach Adenocarcinoma (TCGA): 42.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 90.0;myeloid DC: 88.9" "Group enriched" "Detected in many" 5 "dendritic cells: 88.9;monocytes: 90.0" "Low cancer specificity" "Detected in many" NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 95: Tuft cells - Chemosensory signaling" "unprognostic (4.72e-1)" "unprognostic (2.73e-1)" "unprognostic (1.87e-1)" "unprognostic (1.61e-1)" "unprognostic (1.29e-2)" "unprognostic (4.36e-2)" "unprognostic (3.76e-1)" "potential prognostic favorable (1.13e-5)" "unprognostic (3.58e-3)" "unprognostic (2.23e-1)" "unprognostic (3.09e-1)" "unprognostic (8.40e-2)" "unprognostic (1.67e-1)" "unprognostic (1.94e-1)" "unprognostic (1.56e-1)" "unprognostic (1.16e-1)" "unprognostic (4.65e-2)" "unprognostic (2.26e-1)" "unprognostic (4.64e-1)" ENSG00000257921 ENSG00000257921 "Novel protein" 12 57772660-57797554 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 71: Lymphoma - Inflammatory response" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" "unprognostic (4.61e-2)" ENSG00000258311 ENSG00000258311 "Novel protein" 12 55716036-55724703 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 2.1;Conjunctival goblet cells: 1.9;Epicardial cells: 2.3;Myonuclei: 3.2;Myosatellite cells: 2.1;Neutrophils: 2.1;Paneth cells: 3.9;Parietal cells: 1.8;Rod photoreceptor cells: 2.3" "Cell type enhanced" "Detected in single" "pericyte: 1.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" NA NA "Cluster 32: Basophils - Transcription" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 50: Lymphoma - Unknown function" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "unprognostic (2.15e-2)" "unprognostic (2.93e-2)" "unprognostic (7.33e-3)" "unprognostic (1.11e-2)" "unprognostic (8.63e-2)" "unprognostic (4.60e-2)" "unprognostic (3.16e-1)" "unprognostic (1.47e-1)" "unprognostic (2.05e-3)" "unprognostic (1.38e-1)" "unprognostic (7.41e-2)" "unprognostic (1.92e-3)" "unprognostic (4.88e-2)" "unprognostic (1.84e-1)" "unprognostic (7.98e-2)" "unprognostic (1.22e-1)" "unprognostic (3.48e-2)" "unprognostic (8.94e-2)" "unprognostic (4.28e-2)" "unprognostic (8.71e-2)" "unprognostic (4.26e-2)" "unprognostic (1.97e-2)" "unprognostic (3.73e-1)" "unprognostic (1.03e-1)" "unprognostic (9.84e-2)" "unprognostic (1.14e-1)" "unprognostic (5.33e-3)" "unprognostic (6.14e-2)" ENSG00000258417 ENSG00000258417 "Novel protein" 8 132024238-132085655 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "Testicular Germ Cell Tumor (TCGA): 2.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 38: Sub-cortical - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 68: Foveolar cells - Mucosal defense" "unprognostic (1.47e-1)" ENSG00000258465 ENSG00000258465 "Novel protein" 1 160216800-160285130 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "Adipocytes: 18.8" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "cerebellum: 2.5" "Immune cell enriched" "Detected in single" 8 "basophil: 1.0" "Lineage enriched" "Detected in single" 8 "granulocytes: 1.0" "Not detected" "Not detected" HPA044837 Uncertain NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 35: Non-specific - DNA binding" "Cluster 59: Leukemia - T-cell receptor" "Cluster 7: Non-specific - Transcription" "HPA044837: " "unprognostic (2.68e-1)" ENSG00000258472 ENSG00000258472 "Novel protein" 17 28580012-28614185 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 5 "Proximal tubule cells: 98.7" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" HPA046590 Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 56: Non-specific - Sensory perception" "Cluster 88: Proximal tubular cells - Transmembrane transport" "Vesicles, Plasma membrane" Nucleoplasm "HPA046590: " "unprognostic (6.50e-2)" "unprognostic (3.55e-3)" ENSG00000258529 ENSG00000258529 "Novel protein" 11 111786286-111879425 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "testis: 1.0" "Cell type enhanced" "Detected in some" "Adipocytes: 4.2;Cardiomyocytes: 3.8;Epicardial cells: 2.3;Gastric chief cells: 1.1;Lacrimal acinar cells: 1.8;Parietal cells: 1.8;Sertoli cells: 1.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in single" HPA038575 Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 24: Non-specific - Unknown function" "Cluster 89: Adipocytes - Lipid metabolism" "Endoplasmic reticulum" "HPA038575: " "unprognostic (1.14e-1)" "unprognostic (1.43e-1)" ENSG00000258674 ENSG00000258674 "Novel protein" 19 19516227-19536076 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 9.1" "Group enriched" "Detected in some" 5 "Late spermatids: 13.7;Megakaryocytes: 6.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" "unprognostic (3.12e-2)" "unprognostic (1.15e-1)" "potential prognostic favorable (1.04e-4)" "unprognostic (1.49e-1)" "unprognostic (9.10e-2)" "unprognostic (2.62e-1)" "unprognostic (1.66e-1)" "unprognostic (3.16e-1)" "potential prognostic unfavorable (1.97e-5)" "unprognostic (1.28e-2)" "unprognostic (2.30e-1)" "unprognostic (5.59e-2)" "unprognostic (5.52e-2)" "unprognostic (2.67e-1)" "unprognostic (1.28e-2)" "unprognostic (5.92e-2)" "potential prognostic favorable (3.41e-5)" "unprognostic (8.01e-2)" "unprognostic (5.87e-2)" "unprognostic (1.43e-1)" "unprognostic (4.89e-2)" "unprognostic (1.57e-1)" "unprognostic (2.44e-1)" "unprognostic (5.36e-2)" ENSG00000258691 ENSG00000258691 "Novel protein" 14 96204844-96263929 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "esophagus: 1.7;urinary bladder: 1.4" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 4.7;Endometrial secretory cells: 5.2;Esophageal apical cells: 21.4;Esophageal suprabasal cells: 10.2;Loop of henle epithelial cells: 8.2;Pancreatic acinar cells: 5.9;Pancreatic duct cells: 5.9;Renal collecting duct intercalated cells: 5.3;Salivary duct cells: 5.9" "Cell type enhanced" "Detected in some" "lower rhombic lip: 2.7;upper rhombic lip: 3.0" "Cancer enhanced" "Detected in some" "Kidney Chromophobe (TCGA): 2.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "head and neck cancer: 3.5" NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 15: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "unprognostic (6.71e-2)" "unprognostic (3.27e-3)" "unprognostic (1.81e-2)" ENSG00000258728 ENSG00000258728 "Novel protein (GALT-IL11RA readthrough)" 9 34646631-34661886 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Adipocytes: 2.6;Cardiomyocytes: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 64: Connective tissue cells - ECM organization" "Cluster 89: Adipocytes - Lipid metabolism" ENSG00000258881 ENSG00000258881 "Novel protein" 2 70939318-70995336 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "retina: 1.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 24.8;Distal convoluted tubule cells: 54.5;Renal collecting duct intercalated cells: 113.1;Renal connecting tubule cells: 29.0;Respiratory ionocytes: 17.8;Rod photoreceptor cells: 19.5;Salivary duct cells: 57.7;Salivary ionocytes: 40.9" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in single" "Skin Cutaneous Melanoma (TCGA): 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "skin cancer: 2.9" NA NA "Cluster 40: Non-specific - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" "unprognostic (6.27e-2)" "unprognostic (5.49e-2)" "unprognostic (8.10e-2)" ENSG00000258989 ENSG00000258989 "Novel protein" 14 61529128-61657964 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "retina: 8.2" "Group enriched" "Detected in many" 7 "Epicardial cells: 120.5;Neutrophils: 67.1" "Cell type enhanced" "Detected in some" "endothelial cell: 4.6;leukocyte: 4.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "granulocytes: 1.3;NK-cells: 1.2;T-cells: 1.4" "Low cancer specificity" "Detected in all" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 40: Non-specific - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" "unprognostic (9.21e-3)" "unprognostic (3.93e-3)" "unprognostic (9.45e-2)" "unprognostic (2.55e-3)" "unprognostic (3.03e-2)" "unprognostic (2.52e-1)" "unprognostic (2.04e-1)" "potential prognostic unfavorable (5.03e-5)" "unprognostic (2.00e-2)" "unprognostic (1.97e-1)" "unprognostic (4.33e-2)" "potential prognostic unfavorable (1.83e-5)" "unprognostic (1.67e-1)" "unprognostic (9.58e-2)" "unprognostic (7.90e-2)" "unprognostic (4.23e-1)" "unprognostic (3.38e-1)" "unprognostic (4.33e-2)" "unprognostic (9.35e-2)" "unprognostic (2.11e-1)" "unprognostic (1.23e-2)" "unprognostic (1.26e-2)" "unprognostic (5.13e-2)" "unprognostic (2.40e-1)" "unprognostic (3.59e-2)" "unprognostic (1.07e-1)" ENSG00000259060 ENSG00000259060 "Novel protein" 14 20582892-20609795 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 6 "epididymis: 3.5" "Cell type enhanced" "Detected in single" "Late spermatids: 3.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" ENSG00000259066 ENSG00000259066 "Novel protein" 14 93184973-93218586 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Astrocytes: 4.4;Bergmann glia: 5.1;Brain excitatory neurons: 4.4;Brain inhibitory neurons: 4.3;Choroid plexus epithelial cells: 6.5;Distal convoluted tubule cells: 3.7;Ependymal cells: 2.6;Loop of henle epithelial cells: 5.4;Microglia: 3.4;Oligodendrocyte progenitor cells: 3.8;Oligodendrocytes: 5.0;Other brain neurons: 4.0;Papillary tip epithelial cells: 3.1;Podocytes: 3.4;Proximal tubule cells: 4.3;Renal collecting duct intercalated cells: 4.0;Renal collecting duct principal cells: 4.5;Renal connecting tubule cells: 3.1" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: BICR 18 - Protein kinases" "Cluster 102: Non-specific - Mixed function" "unprognostic (5.19e-2)" ENSG00000259132 ENSG00000259132 "Novel protein" 14 22946270-22982258 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 12.8;Suprabasal keratinocytes: 15.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Bile duct cancer: 7.0" HPA029803 Approved NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 70: Non-specific - Protein processing" "Cluster 51: Neurons - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 26: Keratinocytes - Keratinization" "HPA029803: " "unprognostic (1.60e-1)" "unprognostic (3.06e-3)" "unprognostic (2.66e-2)" "unprognostic (2.69e-1)" "unprognostic (1.23e-1)" "unprognostic (1.51e-1)" "unprognostic (9.75e-2)" "unprognostic (3.12e-2)" "potential prognostic unfavorable (9.80e-5)" "unprognostic (5.10e-2)" "unprognostic (5.27e-3)" "unprognostic (2.45e-2)" "unprognostic (7.39e-2)" "unprognostic (3.88e-2)" "unprognostic (2.36e-3)" "unprognostic (3.50e-1)" "unprognostic (1.71e-1)" "unprognostic (3.04e-2)" "unprognostic (1.84e-1)" "unprognostic (4.97e-2)" "unprognostic (1.30e-1)" "unprognostic (1.27e-1)" "unprognostic (5.22e-3)" "unprognostic (2.17e-3)" "unprognostic (3.29e-2)" "unprognostic (1.72e-1)" "unprognostic (1.31e-1)" ENSG00000259171 ENSG00000259171 "Novel protein, ANG-RNASE4 readthrough" 14 20684587-20700576 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "liver: 107.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "classical monocyte: 9.9;memory B-cell: 3.6;myeloid DC: 5.8" "Group enriched" "Detected in many" 12 "B-cells: 3.6;dendritic cells: 5.8;monocytes: 9.9" "Low cancer specificity" "Detected in many" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 39: Astrocytes - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 108: Fibroblasts - ECM organization" "unprognostic (2.75e-1)" "unprognostic (4.20e-2)" "unprognostic (8.00e-3)" "unprognostic (1.38e-1)" "unprognostic (4.02e-1)" "unprognostic (1.75e-3)" "unprognostic (8.00e-3)" "validated prognostic favorable (2.21e-8)" "validated prognostic favorable (3.78e-4)" "unprognostic (2.45e-1)" "potential prognostic favorable (3.62e-5)" "unprognostic (8.78e-2)" "unprognostic (2.62e-1)" "unprognostic (5.73e-3)" "unprognostic (5.44e-2)" "unprognostic (8.26e-3)" "unprognostic (1.96e-1)" "unprognostic (3.40e-1)" "potential prognostic favorable (5.91e-4)" "unprognostic (1.65e-1)" "unprognostic (1.42e-1)" "potential prognostic unfavorable (4.40e-5)" "unprognostic (2.57e-2)" "unprognostic (1.26e-1)" "unprognostic (1.35e-1)" "unprognostic (7.18e-2)" "unprognostic (2.04e-1)" ENSG00000259371 ENSG00000259371 "Novel protein" 14 24120956-24131829 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Distal convoluted tubule cells: 1.5;Loop of henle epithelial cells: 1.9;Papillary tip epithelial cells: 1.5;Podocytes: 1.3;Proximal tubule cells: 2.5;Renal collecting duct intercalated cells: 1.0;Renal collecting duct principal cells: 2.0;Renal connecting tubule cells: 2.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 105: Non-specific - Mixed function" ENSG00000259784 ENSG00000259784 "Novel protein" 16 2513965-2527955 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "bone marrow: 1.8;intestine: 1.0" "Cell type enhanced" "Detected in some" "Colonocytes: 3.8;Epididymal clear cells: 8.2;Epididymal efferent duct absorptive cells: 4.2;Esophageal apical cells: 4.1;Foveolar cells: 3.2;Megakaryocytes: 12.4;Neutrophils: 3.2;Paneth cells: 3.9;Parietal cells: 3.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 15: Bone marrow - Innate immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 15: Non-specific - Protein processing" "unprognostic (4.21e-1)" "unprognostic (2.20e-1)" "unprognostic (7.39e-3)" ENSG00000260007 ENSG00000260007 "Novel protein" 15 68184032-68229718 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "Adipocytes: 17.9;Cardiomyocytes: 83.2;Epicardial cells: 54.6;Fibro-adipogenic progenitors: 16.2;Retinal bipolar cells: 20.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 52: Non-specific - Mitochondria" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" ENSG00000260170 ENSG00000260170 "Novel protein" 15 45587351-45676314 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "Early spermatids: 10.8;Endometrial glandular cells: 4.4;Endometrial luminal cells: 4.7;Epicardial cells: 4.5" "Cancer enhanced" "Detected in single" "Uterine Corpus Endometrial Carcinoma (TCGA): 1.3" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "neutrophil: 6.3" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" HPA041589 Approved NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 21: Non-specific - Metabolism" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 20: Non-specific - Transcription regulation" "HPA041589: " "unprognostic (7.94e-2)" "unprognostic (2.48e-1)" ENSG00000260272 ENSG00000260272 "Novel protein" 16 2496032-2520218 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "kidney: 1.4" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 3.5;Hofbauer cells: 3.0;Kupffer cells: 5.1;Renal collecting duct intercalated cells: 3.1;Retinal ganglion cells: 7.7" "Cancer enhanced" "Detected in some" "Kidney Chromophobe (TCGA): 3.3;Kidney Renal Papillary Cell Carcinoma (TCGA): 4.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA044712 Uncertain NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" "HPA044712: " "unprognostic (2.59e-1)" "unprognostic (3.94e-2)" ENSG00000260342 ENSG00000260342 "Novel protein" 16 18788063-18801519 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "testis: 13.4" "Cell type enhanced" "Detected in many" "Colonocytes: 9.3;Enteric transient amplifying cells: 14.6;Epididymal basal cells: 12.7;Foveolar cells: 20.2" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 5.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA045307 Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 57: Testis - Spermatogenesis" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 15: Non-specific - Protein processing" "Endoplasmic reticulum" "HPA045307: " "unprognostic (2.61e-2)" "unprognostic (2.27e-3)" "unprognostic (1.97e-1)" "unprognostic (1.80e-1)" "unprognostic (1.19e-1)" "unprognostic (2.44e-1)" "unprognostic (9.77e-2)" "unprognostic (1.35e-1)" "potential prognostic favorable (1.36e-4)" "unprognostic (2.41e-1)" "unprognostic (1.72e-2)" "unprognostic (1.15e-2)" "unprognostic (4.01e-2)" "unprognostic (3.07e-1)" "unprognostic (8.14e-2)" "unprognostic (1.41e-2)" ENSG00000260371 ENSG00000260371 "Novel protein" 16 69335091-69356306 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Retinal ganglion cells: 23.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in single" "testis cancer: 2.5" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 9: Non-specific - Receptor signaling" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 87: B-cells - Adaptive immunity: Humoral response" "unprognostic (3.35e-1)" "unprognostic (3.39e-2)" "unprognostic (9.29e-2)" "unprognostic (2.15e-1)" "unprognostic (2.18e-1)" "unprognostic (1.00e-1)" "unprognostic (8.16e-3)" "unprognostic (3.47e-2)" "unprognostic (2.52e-2)" "unprognostic (2.03e-1)" "unprognostic (1.67e-1)" "unprognostic (7.50e-1)" ENSG00000260537 ENSG00000260537 "Novel protein, DDX19B and DDX19A readthrough" 16 70299194-70372582 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 20.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "HPA046380, HPA066668" Approved Uncertain Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" Nucleoplasm "HPA046380: , HPA066668: " "unprognostic (4.64e-1)" "unprognostic (3.78e-1)" "unprognostic (1.56e-1)" "unprognostic (6.19e-2)" "unprognostic (7.47e-2)" "unprognostic (2.76e-1)" "potential prognostic favorable (9.71e-7)" "unprognostic (5.48e-2)" "unprognostic (2.67e-1)" "unprognostic (5.47e-2)" "unprognostic (6.04e-2)" "unprognostic (6.37e-2)" "unprognostic (2.29e-1)" "unprognostic (4.04e-2)" "unprognostic (1.44e-1)" "unprognostic (2.12e-2)" "unprognostic (1.53e-1)" "unprognostic (2.34e-1)" "unprognostic (1.69e-1)" "unprognostic (3.04e-2)" ENSG00000260643 ENSG00000260643 "Novel protein" 16 81053587-81096296 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.1" "Group enriched" "Detected in some" 4 "Early spermatids: 6.5;Late primary spermatocytes: 1.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" HPA041368 Approved Approved Vesicles NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" Vesicles "HPA041368: " "unprognostic (8.91e-3)" "unprognostic (2.57e-1)" "unprognostic (1.12e-2)" "unprognostic (1.62e-1)" "unprognostic (1.99e-1)" "unprognostic (4.38e-1)" "unprognostic (2.90e-3)" "unprognostic (3.09e-1)" "unprognostic (4.84e-2)" "unprognostic (2.22e-1)" "unprognostic (9.45e-2)" "unprognostic (6.25e-3)" "unprognostic (4.63e-2)" "unprognostic (2.28e-2)" "unprognostic (4.37e-2)" "unprognostic (4.93e-2)" "unprognostic (1.03e-2)" "unprognostic (1.19e-1)" "unprognostic (2.40e-2)" "unprognostic (3.70e-2)" "unprognostic (1.51e-1)" "unprognostic (2.38e-1)" "unprognostic (1.98e-2)" "unprognostic (1.66e-1)" "unprognostic (3.09e-2)" "unprognostic (1.30e-1)" "unprognostic (8.17e-2)" "unprognostic (1.41e-2)" ENSG00000260836 ENSG00000260836 "Novel protein" 15 82536788-82573194 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 1.6;Oligodendrocytes: 2.1;Other brain neurons: 1.4;Parietal cells: 1.8" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA055060 Uncertain Approved "Nucleoli,Endoplasmic reticulum,Cytosol" NA NA "Cluster 14: Neurons - Synaptic function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 80: Oligodendrocytes - Myelination" "Endoplasmic reticulum" "Nucleoli, Cytosol" "HPA055060: " ENSG00000260861 ENSG00000260861 "Novel protein, SIRPB1-SIRPD readthrough" 20 1540144-1620009 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "bone marrow: 2.6;brain: 2.7;lymphoid tissue: 2.4;testis: 3.1" "Cell type enhanced" "Detected in some" "Early spermatids: 4.9;Late primary spermatocytes: 1.4;Late spermatids: 5.8;Microglia: 1.1;Monocyte progenitors: 1.4;monocytes: 1.8;Neutrophil progenitors: 3.8;Neutrophils: 13.4" "Cell type enhanced" "Detected in single" "central nervous system macrophage: 2.1" "Cancer enhanced" "Detected in single" "Skin Cutaneous Melanoma (TCGA): 2.3" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "eosinophil: 78.8;neutrophil: 129.8" "Group enriched" "Detected in many" 7 "granulocytes: 129.8;monocytes: 44.2" "Cancer enhanced" "Detected in some" "thyroid cancer: 2.1" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" "unprognostic (3.16e-1)" ENSG00000260914 ENSG00000260914 "Novel protein" 16 69299682-69322700 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 146.6" "Cell type enhanced" "Detected in some" "Parietal cells: 1.8;Respiratory deuterosomal cells: 1.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA060092 Approved Midbody Yes NA "Cluster 25: Non-specific - Unknown function" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 14: Neurons - Synaptic function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" Midbody "HPA060092: " "unprognostic (1.38e-1)" "unprognostic (1.05e-1)" "unprognostic (1.11e-1)" "unprognostic (3.82e-2)" "unprognostic (3.11e-2)" "unprognostic (3.02e-2)" "unprognostic (2.79e-3)" "unprognostic (2.28e-1)" "potential prognostic favorable (7.86e-11)" "unprognostic (4.86e-2)" "potential prognostic favorable (3.88e-4)" "unprognostic (1.34e-2)" "unprognostic (4.06e-2)" "unprognostic (2.12e-2)" "unprognostic (2.75e-3)" "unprognostic (1.22e-1)" "unprognostic (1.83e-1)" "unprognostic (2.76e-1)" "unprognostic (6.16e-2)" "unprognostic (5.24e-2)" "unprognostic (3.27e-2)" "unprognostic (1.80e-1)" "unprognostic (1.45e-1)" "unprognostic (9.22e-2)" "unprognostic (1.93e-1)" "unprognostic (1.63e-1)" "unprognostic (6.95e-2)" ENSG00000261130 ENSG00000261130 "Novel protein" 16 15395754-15515348 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Astrocytes: 1.4;Brain excitatory neurons: 2.9;Brain inhibitory neurons: 3.0;Choroid plexus epithelial cells: 1.4;Ependymal cells: 1.1;Oligodendrocyte progenitor cells: 1.9;Oligodendrocytes: 1.1;Other brain neurons: 2.2;Proximal tubule cells: 1.2" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 18: Liver cancer - Metabolism" "Cluster 109: Neurons - Neuronal signaling" ENSG00000261341 ENSG00000261341 "Novel protein" 19 50776141-50793142 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Tissue enriched" "Detected in some" 41 "testis: 346.8" "Cell type enriched" "Detected in many" 7 "Late spermatids: 10828.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Late spermatids" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 79: Testis - Spermatogenesis" "Cluster 15: Non-specific - Transcription" "Cluster 60: Prostate cancer - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" "unprognostic (1.44e-1)" "unprognostic (1.65e-2)" "unprognostic (6.55e-2)" ENSG00000261717 ENSG00000261717 "Novel TMEM170A-CFDP1 readthrough protein" 16 75412684-75464706 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "skeletal muscle: 2.1;testis: 1.7" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 32.8;Cone photoreceptor cells: 8.3" "Cell type enhanced" "Detected in many" "oligodendrocyte: 10.3" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 6.9;Uterine Corpus Endometrial Carcinoma (TCGA): 13.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" HPA041316 Uncertain NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" "HPA041316: " "unprognostic (8.24e-2)" "unprognostic (9.07e-2)" "unprognostic (2.02e-1)" "unprognostic (2.72e-2)" "unprognostic (2.59e-2)" "unprognostic (1.40e-1)" "unprognostic (2.37e-3)" "unprognostic (7.26e-3)" "unprognostic (2.96e-1)" "unprognostic (1.24e-1)" ENSG00000261793 ENSG00000261793 "Novel transcript, TMEM210 and LRRC26 readthrough" 9 137168854-137171984 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 4 "salivary gland: 43.5" "Cell type enhanced" "Detected in some" "Early spermatids: 2.6;Late spermatids: 3.6" "Cancer enriched" "Detected in many" 4 "Prostate Adenocarcinoma (TCGA): 26.9" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 31 "plasmacytoid DC: 3.1" "Lineage enriched" "Detected in single" 31 "dendritic cells: 3.1" "Cancer enhanced" "Detected in some" "prostate cancer: 2.4" NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 82: Salivary gland - Secretion" "Cluster 15: Non-specific - Transcription" "Cluster 6: Leukemia - Signal transduction" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" "unprognostic (3.66e-1)" "unprognostic (6.12e-2)" "unprognostic (2.81e-2)" "unprognostic (3.08e-1)" "unprognostic (2.48e-1)" "unprognostic (7.94e-2)" "unprognostic (5.61e-3)" "unprognostic (2.86e-1)" "potential prognostic unfavorable (2.49e-5)" "unprognostic (2.20e-2)" "unprognostic (1.83e-1)" ENSG00000261832 ENSG00000261832 "Novel protein" 16 28456371-28492098 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Neutrophils: 2.9;Papillary tip epithelial cells: 3.1;Renal collecting duct principal cells: 3.9;Tuft cells: 11.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA053611 Uncertain Approved Nucleoplasm NA NA "Cluster 95: Tuft cells - Chemosensory signaling" Nucleoplasm "HPA053611: " ENSG00000262660 ENSG00000262660 "Novel protein" 17 81703371-81720539 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 2.2;skeletal muscle: 1.0" "Cell type enhanced" "Detected in many" "Colonocytes: 38.6;Enteric stem cells: 31.5;Enteric transient amplifying cells: 43.9;Enterocytes: 23.7;Goblet cells: 22.0;Neuroendocrine cells: 13.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA022853, HPA023043, HPA023048" Approved Supported Mitochondria NA NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 4 Mitochondria "HPA022853: , HPA023043: , HPA023048: " "unprognostic (2.70e-1)" "unprognostic (2.82e-1)" "unprognostic (2.38e-2)" "unprognostic (1.95e-1)" "unprognostic (4.32e-1)" "unprognostic (2.19e-1)" "unprognostic (1.54e-1)" ENSG00000263020 ENSG00000263020 "Novel protein" 6 31666102-31673546 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder Urothelial Carcinoma (TCGA): 2.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA005944, HPA048307" Uncertain NA NA "Cluster 64: Non-specific - Transcription" "Cluster 16: Thyroid cancer - Neuronal signaling" "HPA005944: , HPA048307: " "unprognostic (1.28e-1)" "unprognostic (9.22e-2)" "potential prognostic favorable (1.55e-4)" "unprognostic (1.64e-1)" "unprognostic (4.11e-2)" "unprognostic (2.72e-1)" ENSG00000263620 ENSG00000263620 "Novel protein" 17 8150816-8162975 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 45.5" "Cell type enriched" "Detected in some" 6 "Epicardial cells: 43.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 24: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 42: Non-specific - Unknown function" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" "unprognostic (1.28e-2)" "unprognostic (8.52e-2)" "unprognostic (3.38e-1)" "unprognostic (3.20e-1)" "unprognostic (9.38e-2)" "unprognostic (3.82e-2)" "unprognostic (7.31e-2)" "unprognostic (7.54e-2)" "unprognostic (1.89e-2)" "unprognostic (1.49e-2)" "unprognostic (6.26e-2)" "unprognostic (6.18e-2)" "unprognostic (1.86e-1)" "unprognostic (1.96e-3)" "unprognostic (2.05e-2)" "potential prognostic favorable (1.90e-5)" "unprognostic (1.55e-1)" "unprognostic (2.04e-1)" "unprognostic (3.32e-1)" "unprognostic (4.05e-2)" "unprognostic (7.97e-3)" "potential prognostic unfavorable (2.86e-4)" "unprognostic (6.89e-2)" "unprognostic (5.23e-3)" "unprognostic (1.27e-2)" ENSG00000264668 ENSG00000264668 "Novel protein" 8 143247110-143276403 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "brain: 1.2" "Cell type enhanced" "Detected in many" "Colonocytes: 6.2;Cone photoreceptor cells: 6.2;Hepatic stellate cells: 6.5;Proximal tubule cells: 5.3;Retinal horizontal cells: 6.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047232, HPA056268" Uncertain Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Plasma membrane" NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" "Nucleoli, Nucleoli rim" "Nucleoplasm, Plasma membrane" "HPA047232: , HPA056268: " ENSG00000265118 ENSG00000265118 "Novel protein" 17 31305213-31318831 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 4 "lymphoid tissue: 7.8" "Cell type enhanced" "Detected in some" "Adipocytes: 1.9;Cardiomyocytes: 8.4;Epicardial cells: 2.3;Neutrophils: 4.7;NK-cells: 2.1;Oligodendrocytes: 2.7;Plasma cells: 1.3;Retinal horizontal cells: 2.0;T-cells: 1.2" "Cell type enriched" "Detected in single" 5 "oligodendrocyte: 4.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 221.1" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Leukemia: 2.0;lymphoma: 2.0;Myeloma: 3.1" HPA045033 Uncertain Approved "Golgi apparatus,Vesicles,Plasma membrane,Primary cilium,Primary cilium transition zone,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 30: White matter - Myelination" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "Golgi apparatus, Vesicles, Plasma membrane, Primary cilium" "Primary cilium transition zone, Cytosol" "HPA045033: " "unprognostic (5.05e-3)" "unprognostic (9.27e-2)" "unprognostic (3.23e-1)" "unprognostic (5.47e-3)" "unprognostic (2.19e-1)" "unprognostic (1.08e-1)" "unprognostic (6.15e-2)" "unprognostic (2.86e-3)" "unprognostic (4.78e-2)" "unprognostic (2.96e-1)" ENSG00000265303 ENSG00000265303 "Novel protein" 17 59197566-59215226 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in single" "Foveolar cells: 1.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "NK-cell: 1.7" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in single" 12 "Bile duct cancer: 11.6" NA NA "Cluster 68: Non-specific - Basic cellular processes" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 27: Non-specific - Cell proliferation" "unprognostic (2.95e-1)" "unprognostic (2.11e-1)" "unprognostic (2.64e-2)" "unprognostic (1.02e-1)" "unprognostic (4.62e-2)" "unprognostic (2.94e-1)" "unprognostic (2.27e-1)" "potential prognostic unfavorable (1.26e-6)" "unprognostic (4.96e-2)" "unprognostic (1.45e-2)" "unprognostic (8.50e-2)" "unprognostic (3.38e-3)" "unprognostic (1.76e-1)" "unprognostic (6.49e-3)" "unprognostic (3.00e-1)" "unprognostic (7.82e-3)" "unprognostic (6.80e-2)" "unprognostic (1.29e-1)" "unprognostic (2.76e-2)" "unprognostic (1.58e-1)" ENSG00000266202 ENSG00000266202 "Novel protein" 17 27798806-27893365 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "pancreas: 1.6" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 14.8;Brain inhibitory neurons: 17.9;Distal convoluted tubule cells: 20.3;Myonuclei: 16.3;Podocytes: 15.5;Renal connecting tubule cells: 15.3;Retinal amacrine cells: 17.9;Retinal ganglion cells: 30.9;Undifferentiated spermatogonia: 22.7" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA023051 Uncertain NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 24: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Neurons - Synaptic function & neurogenesis" "HPA023051: " ENSG00000266953 ENSG00000266953 "Novel protein, readthrough between GPI and PDCD2" 19 34396315-34409364 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "bone marrow: 1.0;retina: 2.4;skeletal muscle: 2.5" "Cell type enhanced" "Detected in some" "Epididymal clear cells: 2.0;Medullary thymic epithelial cells: 2.4;Myonuclei: 2.0;Neutrophil progenitors: 4.1;Paneth cells: 7.7;Retinal horizontal cells: 4.0" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 6.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 15: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 37: Neutrophil progenitors - Granulopoiesis" "unprognostic (1.36e-1)" "unprognostic (3.70e-3)" "unprognostic (1.72e-1)" "unprognostic (6.68e-3)" "unprognostic (2.20e-2)" "unprognostic (2.10e-1)" "unprognostic (1.12e-2)" "unprognostic (1.07e-2)" "unprognostic (1.83e-1)" ENSG00000267001 ENSG00000267001 "Novel protein" 19 2717769-2740048 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 13.0" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 6.2;Epicardial cells: 4.5;Late primary spermatocytes: 2.8;Megakaryocyte-Erythroid progenitors: 1.3;Myosatellite cells: 1.2;Retinal horizontal cells: 4.0" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" HPA058526 Uncertain NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 67: Testis - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" "HPA058526: " "unprognostic (2.18e-2)" "unprognostic (1.28e-1)" "unprognostic (6.59e-2)" "unprognostic (3.07e-2)" "unprognostic (1.23e-1)" "unprognostic (1.52e-1)" "potential prognostic favorable (2.81e-4)" "unprognostic (7.96e-2)" "unprognostic (1.71e-1)" "unprognostic (5.98e-2)" "unprognostic (1.98e-1)" "unprognostic (7.36e-2)" "unprognostic (1.18e-3)" "unprognostic (4.19e-2)" "unprognostic (1.24e-1)" "unprognostic (1.26e-1)" "unprognostic (8.83e-2)" "unprognostic (2.31e-2)" "unprognostic (1.90e-1)" "unprognostic (4.07e-1)" "unprognostic (2.00e-1)" "unprognostic (1.65e-1)" "unprognostic (3.41e-1)" "unprognostic (1.30e-1)" "unprognostic (2.32e-1)" ENSG00000267140 ENSG00000267140 "Novel protein" 18 35443871-35497940 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 4.5" "Cell type enhanced" "Detected in single" "Lymphatic endothelial cells: 1.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 61: Non-specific - Transcription" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "unprognostic (8.17e-3)" "unprognostic (9.45e-2)" "unprognostic (1.84e-1)" "unprognostic (1.47e-1)" "unprognostic (2.23e-1)" "potential prognostic unfavorable (4.14e-4)" "unprognostic (6.13e-2)" "unprognostic (4.05e-2)" "unprognostic (1.77e-3)" "unprognostic (1.31e-2)" "unprognostic (1.98e-2)" "unprognostic (8.75e-2)" "unprognostic (2.77e-1)" "unprognostic (8.01e-2)" ENSG00000267157 ENSG00000267157 "Novel protein" 19 5784005-5785619 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 7 "Cardiomyocytes: 1.0" "Cancer enhanced" "Detected in single" "Uterine Corpus Endometrial Carcinoma (TCGA): 1.8" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" NA NA "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 23: Non-specific - Transcription" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "unprognostic (1.08e-1)" "unprognostic (1.22e-1)" "unprognostic (4.18e-1)" ENSG00000267168 ENSG00000267168 "Novel protein" 17 76732978-76738522 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "Cardiomyocytes: 308.4;Epicardial cells: 391.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in single" "Uterine Corpus Endometrial Carcinoma (TCGA): 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" "unprognostic (2.06e-1)" ENSG00000267173 ENSG00000267173 "Novel protein" 19 44329695-44401608 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Adipocytes: 1.9;Adrenal cortex cells: 1.8;Distal convoluted tubule cells: 1.6;Early spermatids: 2.2;Granulosa cells: 1.6;Late primary spermatocytes: 1.8;Mucous neck cells: 4.4;Pituitary stem cells: 2.1;Podocytes: 2.1;Retinal amacrine cells: 2.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" ENSG00000267179 ENSG00000267179 "Novel protein" 19 11925075-11979290 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 8.9;Loop of henle epithelial cells: 10.9;Proximal tubule cells: 9.0;Renal collecting duct principal cells: 7.7;Renal connecting tubule cells: 7.9" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047845 Uncertain Uncertain Nucleoplasm NA NA "Cluster 41: Basophils - Unknown function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" Nucleoplasm "HPA047845: " "unprognostic (1.32e-2)" ENSG00000267261 ENSG00000267261 "Novel protein" 17 42119674-42154916 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "Colonocytes: 28.1;Enteric stem cells: 14.4;Enteric transient amplifying cells: 17.2;Enterocytes: 33.3;Epididymal clear cells: 12.2;Epididymal efferent duct absorptive cells: 14.6;Epididymal efferent duct ciliated cells: 12.6;Epididymal principal cells: 11.4;Foveolar cells: 13.4;Gastric chief cells: 13.1;Goblet cells: 16.5;Paneth cells: 15.5;Parietal cells: 21.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" NA NA "Cluster 14: Neurons - Synaptic function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 15: Non-specific - Protein processing" ENSG00000267318 ENSG00000267318 "Novel protein" 17 59940908-59973101 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "skeletal muscle: 23.5;tongue: 21.4" "Group enriched" "Detected in many" 6 "Adipocytes: 115.7;Cardiomyocytes: 280.6;Epicardial cells: 116.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 52: Non-specific - Cellular respiration" "Cluster 25: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 89: Adipocytes - Lipid metabolism" "unprognostic (6.85e-2)" "unprognostic (1.51e-1)" "unprognostic (5.88e-3)" "unprognostic (1.67e-1)" "unprognostic (1.73e-1)" "unprognostic (2.33e-1)" "unprognostic (3.41e-2)" "unprognostic (2.19e-2)" "unprognostic (1.59e-2)" "potential prognostic favorable (1.35e-5)" "unprognostic (9.82e-2)" "unprognostic (4.56e-2)" "unprognostic (1.26e-1)" "unprognostic (3.59e-2)" "unprognostic (1.19e-1)" "unprognostic (5.94e-3)" "unprognostic (1.10e-2)" "unprognostic (5.37e-1)" "unprognostic (1.97e-1)" "unprognostic (3.59e-2)" "unprognostic (1.42e-1)" "unprognostic (1.89e-1)" "unprognostic (9.39e-2)" "unprognostic (1.79e-1)" ENSG00000267335 ENSG00000267335 "Novel protein" 19 49022953-49036895 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 6 "pituitary gland: 15.5" "Cell type enhanced" "Detected in some" "pDCs: 1.3;Retinal ganglion cells: 3.9" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Pancreatic Adenocarcinoma (TCGA): 1.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" HPA038925 Uncertain "Secreted - unknown location" NA NA "Cluster 20: Pituitary gland - Hormone signaling" "Cluster 29: Forebrain - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" "HPA038925: " "unprognostic (1.26e-2)" ENSG00000267360 ENSG00000267360 "Novel protein" 19 37093019-37210512 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "Adipocytes: 27.4;Cardiomyocytes: 37.5;Cone photoreceptor cells: 16.6;Fibro-adipogenic progenitors: 30.0;Myonuclei: 34.5;Myosatellite cells: 17.0;Retinal bipolar cells: 17.2;Retinal horizontal cells: 18.0" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 15: Non-specific - Transcription" "Cluster 59: Leukemia - T-cell receptor" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "unprognostic (2.65e-2)" ENSG00000267561 ENSG00000267561 "Novel protein" 1 86993009-87169204 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 18.1" "Cell type enhanced" "Detected in some" "Adrenal cortex cells: 3.1;Epicardial cells: 2.3;Mast cells: 2.1;Pancreatic islet cells: 2.1;Retinal amacrine cells: 2.1;Retinal ganglion cells: 3.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "eosinophil: 1.7" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.7" "Group enriched" "Detected in some" 5 "Leukemia: 3.4;Rhabdoid: 7.7" "HPA043069, HPA043603" Approved Uncertain Mitochondria NA NA "Cluster 61: Non-specific - Transcription" "Cluster 53: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" Mitochondria "HPA043069: , HPA043603: " "unprognostic (1.72e-1)" "unprognostic (1.12e-2)" "unprognostic (1.05e-1)" "unprognostic (4.40e-2)" "unprognostic (2.85e-2)" "unprognostic (6.81e-3)" "unprognostic (2.06e-1)" "unprognostic (2.25e-2)" "unprognostic (1.55e-1)" "unprognostic (1.51e-1)" "unprognostic (2.20e-1)" "unprognostic (3.21e-1)" "unprognostic (4.43e-1)" "unprognostic (1.77e-2)" "unprognostic (1.91e-2)" "unprognostic (1.84e-1)" "unprognostic (2.04e-1)" ENSG00000267618 ENSG00000267618 "RAD51L3-RFFL readthrough" 17 35011349-35121493 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "testis: 4.1" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 1.2;Early spermatids: 1.2;Late spermatids: 2.6;Neutrophil progenitors: 1.4" "Low cell type specificity" "Detected in single" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 7 "NK-cell: 1.2" "Lineage enriched" "Detected in single" 7 "NK-cells: 1.2" "Low cancer specificity" "Detected in single" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 53: Neurons - Mixed function" "Cluster 61: BICR 18 - Protein kinases" "Cluster 37: Neutrophil progenitors - Granulopoiesis" "unprognostic (5.56e-1)" "unprognostic (1.67e-1)" ENSG00000267740 ENSG00000267740 "Novel protein" 19 5866171-5903787 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 5.2;Hematopoietic stem cells: 6.3;Medullary thymic epithelial cells: 4.8;Retinal horizontal cells: 6.0" "Low cell type specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 12.7" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" HPA072209 Approved "Mitochondria,Perinuclear theca,Principal piece,End piece" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 51: Secretory epithelial cells - Mixed function" "Mitochondria, End piece" "Perinuclear theca, Principal piece" "HPA072209: " "unprognostic (1.58e-2)" "unprognostic (1.23e-3)" "unprognostic (1.21e-1)" "unprognostic (3.94e-2)" "unprognostic (3.22e-1)" "unprognostic (1.65e-1)" "unprognostic (2.21e-1)" "unprognostic (2.81e-1)" "potential prognostic unfavorable (8.89e-4)" "unprognostic (1.33e-3)" "unprognostic (1.15e-1)" "unprognostic (5.72e-3)" "unprognostic (1.70e-1)" "unprognostic (1.67e-2)" "unprognostic (9.51e-2)" "unprognostic (3.45e-2)" "unprognostic (1.16e-1)" "unprognostic (3.23e-1)" "unprognostic (2.94e-2)" "unprognostic (6.54e-2)" "unprognostic (6.02e-2)" ENSG00000267748 ENSG00000267748 "Novel protein" 19 38289151-38304910 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "blood vessel: 5.8;salivary gland: 10.9" "Cell type enhanced" "Detected in many" "Breast lactating cells: 16.1;Endometrial glandular cells: 21.7;Endometrial luminal cells: 19.2;Salivary acinar cells: 14.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 60: Stomach - Digestion" "Cluster 15: Kidney cancer - Membrane components" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" "unprognostic (2.10e-1)" "unprognostic (2.14e-3)" "unprognostic (3.24e-3)" "unprognostic (5.57e-2)" "unprognostic (1.99e-1)" "unprognostic (8.54e-2)" "unprognostic (2.37e-1)" "unprognostic (1.40e-2)" "unprognostic (2.11e-1)" "unprognostic (3.11e-1)" "unprognostic (4.47e-2)" "unprognostic (2.95e-2)" "potential prognostic unfavorable (4.73e-4)" "unprognostic (1.52e-3)" "unprognostic (2.02e-2)" "unprognostic (1.42e-1)" "unprognostic (3.67e-1)" "unprognostic (3.49e-2)" "unprognostic (3.11e-1)" "unprognostic (9.18e-2)" "unprognostic (2.48e-1)" "unprognostic (2.08e-2)" ENSG00000267881 ENSG00000267881 "Novel protein, readthrough between CEACAM5-CEACAM6" 19 41708657-41756737 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 4 "intestine: 3.1" "Group enriched" "Detected in some" 5 "Colonocytes: 209.3;Esophageal apical cells: 59.7;Foveolar cells: 141.8;Goblet cells: 146.7" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 4.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Gallbladder cancer: 1.0" NA NA "Cluster 17: Intestine - Digestion" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" "unprognostic (5.00e-2)" "unprognostic (1.75e-1)" "unprognostic (1.39e-1)" "unprognostic (3.08e-1)" "unprognostic (7.55e-2)" "unprognostic (7.05e-2)" "unprognostic (2.06e-1)" ENSG00000267952 ENSG00000267952 "Novel transcript" 19 7507052-7519622 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "retina: 4.7;skeletal muscle: 11.5" "Cell type enhanced" "Detected in some" "Early spermatids: 4.0;Endometrial luminal cells: 4.3;Endometrial secretory cells: 1.9;Enteric stem cells: 2.5;Gastric chief cells: 2.2;Gonadotrophs: 4.5;Late spermatids: 7.4;Neuroendocrine cells: 1.9;Retinal ganglion cells: 3.9;Rod photoreceptor cells: 8.1" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 14 "testis cancer: 10.8" NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 79: Photoreceptor cells - Phototransduction" "unprognostic (2.89e-1)" "unprognostic (2.61e-2)" "unprognostic (1.92e-1)" "potential prognostic favorable (7.46e-4)" "unprognostic (8.90e-2)" "unprognostic (7.37e-1)" "unprognostic (3.48e-1)" "unprognostic (2.27e-1)" "unprognostic (1.27e-1)" "unprognostic (3.18e-2)" "unprognostic (3.59e-1)" "unprognostic (2.43e-1)" "unprognostic (8.97e-3)" "unprognostic (5.88e-1)" "unprognostic (2.74e-1)" "unprognostic (3.84e-2)" ENSG00000268083 ENSG00000268083 "Novel protein" 19 38817471-38840178 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skeletal muscle: 1.3" "Cell type enhanced" "Detected in some" "Papillary tip epithelial cells: 1.3;Renal connecting tubule cells: 1.3" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in single" "Leukemia: 1.3" "HPA002907, HPA051748" Uncertain Uncertain Mitochondria NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 35: RS4;11 - Unknown function" "Cluster 102: Non-specific - Mixed function" Mitochondria "HPA002907: , HPA051748: " "unprognostic (9.43e-2)" "unprognostic (1.44e-2)" "unprognostic (5.43e-2)" "unprognostic (2.37e-2)" "unprognostic (1.24e-1)" "unprognostic (1.28e-2)" "unprognostic (3.84e-1)" "potential prognostic unfavorable (8.77e-4)" "unprognostic (2.54e-1)" "unprognostic (9.78e-2)" "unprognostic (2.76e-1)" "unprognostic (8.00e-2)" "unprognostic (3.29e-3)" "unprognostic (3.62e-3)" "unprognostic (6.14e-2)" "unprognostic (1.33e-1)" "unprognostic (3.64e-2)" "unprognostic (3.76e-2)" "unprognostic (1.54e-1)" "unprognostic (1.85e-1)" "unprognostic (1.31e-1)" ENSG00000268133 ENSG00000268133 "Novel protein" 19 57363566-57398584 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 2.0;Cone photoreceptor cells: 4.1;Epididymal clear cells: 2.0;Müller glia: 2.1;Pancreatic islet cells: 2.1;Retinal horizontal cells: 4.0;Thymocytes: 3.4" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 58: Non-specific - Nuclear processes" "Cluster 20: Non-specific - Transcription regulation" "unprognostic (7.07e-3)" ENSG00000268163 ENSG00000268163 "Novel transcript" 19 57437970-57477536 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "retina: 1.1;skeletal muscle: 1.0" "Cell type enhanced" "Detected in many" "Bergmann glia: 64.7;Choroid plexus epithelial cells: 73.4;Myonuclei: 139.3;Rod photoreceptor cells: 61.6;Sertoli cells: 85.9;Somatotrophs: 66.9;Thyrotrophs: 69.7" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 16: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 55: Myocytes - Oxidative muscle function" "unprognostic (5.67e-2)" "unprognostic (2.02e-3)" ENSG00000268361 ENSG00000268361 "Novel protein" 19 43554692-43593036 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 4 "brain: 1.0" "Cell type enhanced" "Detected in some" "Adipocytes: 5.5;Epicardial cells: 22.7;Fibroblasts: 4.6;Hepatic stellate cells: 12.9;Retinal amacrine cells: 4.4;Retinal horizontal cells: 6.0" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 64: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" ENSG00000268434 ENSG00000268434 "Novel protein" 19 45779437-45785973 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "skeletal muscle: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney Chromophobe (TCGA): 2.4;Uterine Corpus Endometrial Carcinoma (TCGA): 2.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 61: BICR 18 - Protein kinases" "Cluster 110: Mural cells - ECM organization" ENSG00000268465 ENSG00000268465 "Novel protein" 19 48465837-48472431 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "intestine: 1.1;retina: 4.6;testis: 1.5" "Cell type enhanced" "Detected in some" "Early spermatids: 10.0;Late primary spermatocytes: 6.1;Paneth cells: 7.7;Retinal ganglion cells: 7.7;Rod photoreceptor cells: 24.9" "Cancer enhanced" "Detected in some" "Bladder Urothelial Carcinoma (TCGA): 1.0;Uterine Corpus Endometrial Carcinoma (TCGA): 1.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA060662 Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 42: Retina - Visual perception" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 61: BICR 18 - Protein kinases" "Cluster 79: Photoreceptor cells - Phototransduction" "Plasma membrane, Cytosol" "HPA060662: " ENSG00000268533 ENSG00000268533 "Novel protein" 19 57394183-57438457 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "retina: 7.8;skin 1: 6.2" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 22.0;Brain inhibitory neurons: 21.8;Cardiomyocytes: 19.3;Choroid plexus epithelial cells: 20.2;Myonuclei: 21.9;Other brain neurons: 19.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 40: Non-specific - Mixed function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 56: Non-specific - Sensory perception" "Cluster 109: Neurons - Neuronal signaling" "unprognostic (5.59e-3)" "unprognostic (1.20e-1)" "unprognostic (2.85e-1)" "unprognostic (2.49e-1)" "unprognostic (3.24e-2)" "potential prognostic unfavorable (8.22e-4)" "unprognostic (1.57e-1)" "unprognostic (1.05e-1)" "unprognostic (5.37e-2)" "unprognostic (3.46e-2)" "potential prognostic favorable (1.32e-4)" "unprognostic (1.12e-1)" "unprognostic (2.42e-1)" "unprognostic (7.20e-3)" "unprognostic (7.85e-2)" "unprognostic (7.40e-3)" "unprognostic (2.82e-1)" "unprognostic (7.47e-2)" "unprognostic (3.49e-2)" ENSG00000268643 ENSG00000268643 "Novel protein" 19 42234583-42255132 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 10.0" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 4.7;Breast secretory cells: 8.3;Cardiomyocytes: 8.7;Epicardial cells: 6.8;Salivary myoepithelial cells: 10.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 6.5;Stomach Adenocarcinoma (TCGA): 4.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "testis cancer: 19.2" HPA006495 Approved Nucleoplasm,Cytosol NA NA "Cluster 42: Retina - Visual perception" "Cluster 55: Non-specific - Transcription" "Cluster 61: BICR 18 - Protein kinases" "Cluster 20: Non-specific - Transcription regulation" Nucleoplasm Cytosol "HPA006495: " "unprognostic (6.96e-3)" "unprognostic (1.54e-1)" "unprognostic (4.15e-3)" "unprognostic (4.49e-3)" "unprognostic (4.98e-2)" "unprognostic (3.42e-1)" "unprognostic (5.72e-2)" "unprognostic (8.11e-2)" "unprognostic (1.19e-1)" ENSG00000268655 ENSG00000268655 "Novel protein" 19 49017968-49020549 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "pancreas: 8.5;testis: 2.6" "Cell type enhanced" "Detected in some" "Early spermatids: 5.1;Late primary spermatocytes: 8.3;Late spermatids: 5.1;Oocytes: 23.0" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Exocrine glandular cells, Pituitary gland - Gonadotropes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 15: Non-specific - Transcription" "Cluster 72: Neuronal - Signal transduction" "Cluster 41: Oocytes - Oogenesis" ENSG00000268674 ENSG00000268674 P0DMU3 Unmapped 35407-35916 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "HPA043267, HPA043292" Uncertain NA NA "Cluster 24: Non-specific - Transcription" "Cluster 22: Epididymis - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "HPA043267: , HPA043292: " ENSG00000268750 ENSG00000268750 "Novel protein" 19 57819719-57858941 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 10.6;Cardiomyocytes: 7.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" HPA056213 Uncertain NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 60: Stomach - Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" "HPA056213: " "unprognostic (7.39e-3)" "unprognostic (1.60e-1)" "unprognostic (1.20e-2)" "unprognostic (4.53e-2)" "unprognostic (3.65e-1)" "unprognostic (2.08e-1)" "unprognostic (3.23e-2)" "unprognostic (1.71e-1)" "unprognostic (5.37e-2)" "unprognostic (1.40e-2)" "unprognostic (2.85e-1)" "unprognostic (9.53e-2)" "unprognostic (2.76e-1)" "unprognostic (2.53e-3)" "unprognostic (2.14e-1)" "unprognostic (6.80e-3)" "unprognostic (1.46e-1)" "unprognostic (3.94e-1)" "unprognostic (3.26e-1)" "unprognostic (3.45e-3)" "unprognostic (2.35e-1)" "potential prognostic favorable (8.41e-4)" "unprognostic (3.11e-1)" "unprognostic (2.03e-2)" "unprognostic (1.04e-1)" "unprognostic (3.77e-1)" "potential prognostic unfavorable (1.69e-4)" "unprognostic (1.25e-1)" ENSG00000268790 ENSG00000268790 "Novel protein" 19 16577642-16660115 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "skeletal muscle: 1.7" "Cell type enhanced" "Detected in some" "Adipocytes: 3.3;Gastric chief cells: 1.1;Myonuclei: 2.5;pDCs: 1.8;Retinal horizontal cells: 4.0" "Cell type enhanced" "Detected in single" "upper rhombic lip: 1.1" "Cancer enriched" "Detected in single" 8 "Uterine Corpus Endometrial Carcinoma (TCGA): 6.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 49: HMC-1 - Innate immune response" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" "unprognostic (9.03e-3)" ENSG00000268870 ENSG00000268870 "Novel zinc finger protein" 19 12391949-12441082 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "Early spermatids: 21.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "HPA003150, HPA018683" Uncertain Uncertain "Nucleoplasm,Centriolar satellite" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 30: White matter - Myelination" "Cluster 4: Non-specific - Transcription" "Cluster 29: Neutrophils - Innate immune cellular maintenance" Nucleoplasm "Centriolar satellite" "HPA003150: , HPA018683: " "unprognostic (6.95e-2)" "unprognostic (4.01e-2)" "unprognostic (2.21e-2)" "unprognostic (2.07e-2)" "unprognostic (8.38e-2)" ENSG00000269026 ENSG00000269026 "Novel protein" 19 57682045-57753575 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 61.5;Myonuclei: 38.6;Sertoli cells: 52.0" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" HPA068553 Approved Nucleoplasm NA NA "Cluster 4: Non-specific - Transcription" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" Nucleoplasm "HPA068553: " "unprognostic (2.26e-2)" "unprognostic (3.91e-2)" ENSG00000269035 ENSG00000269035 "Novel protein" 19 17436611-17460804 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "Cone photoreceptor cells: 207.0;Retinal pigment epithelial cells: 76.7;Rod photoreceptor cells: 276.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA041580 Approved Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 79: Photoreceptor cells - Phototransduction" "Nuclear membrane" "Nucleoplasm, Cytosol" "HPA041580: " ENSG00000269095 ENSG00000269095 "Novel protein" 19 17235940-17255448 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Adipocytes: 1.0;Cone photoreceptor cells: 2.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 3.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 25: Non-specific - Transcription" "Cluster 34: Testis cancer - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "unprognostic (9.84e-2)" "unprognostic (5.76e-1)" "unprognostic (2.41e-1)" "unprognostic (3.75e-1)" ENSG00000269533 ENSG00000269533 "Novel transcript" 19 57389884-57419994 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 4: Non-specific - Transcription" "unprognostic (3.04e-1)" ENSG00000269547 ENSG00000269547 "Novel protein" 19 38915404-38949855 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Astrocytes: 1.7;Choroid plexus epithelial cells: 2.2;Distal convoluted tubule cells: 3.6;Loop of henle epithelial cells: 4.2;Oligodendrocyte progenitor cells: 1.2;Podocytes: 5.7;Proximal tubule cells: 11.3;Renal collecting duct intercalated cells: 3.2;Renal collecting duct principal cells: 1.7;Renal connecting tubule cells: 3.5" "Low cell type specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA052730, HPA056957" Uncertain Uncertain Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 4: Non-specific - Transcription" "Cluster 88: Proximal tubular cells - Transmembrane transport" "Nucleoplasm, Mitochondria" Vesicles "HPA052730: , HPA056957: " ENSG00000269590 ENSG00000269590 "Novel protein" 19 12664828-12669397 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 1.1;lymphoid tissue: 1.3;skeletal muscle: 1.2" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 18.2;Enterocytes: 3.9;Gastric progenitor cells: 3.8;Oocytes: 9.2;Parietal cells: 3.5;Retinal ganglion cells: 3.9" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in single" "Uterine Corpus Endometrial Carcinoma (TCGA): 1.6" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "neutrophil: 2.5" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.5" "Not detected" "Not detected" HPA065685 Uncertain Approved "Nuclear membrane,Endoplasmic reticulum" NA NA "Cluster 32: Basophils - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 20: Myeloma - Immune response" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" "Nuclear membrane, Endoplasmic reticulum" "HPA065685: " ENSG00000269711 ENSG00000269711 "Novel protein" 19 7678501-7682854 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 7 "bone marrow: 20.8;intestine: 7.3;lung: 17.8;lymphoid tissue: 11.9" "Group enriched" "Detected in some" 5 "Neutrophil progenitors: 7.6;Neutrophils: 16.9" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 9.6" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "classical monocyte: 192.8;neutrophil: 82.3" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in single" 5 "Leukemia: 4.8" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" "unprognostic (9.03e-2)" "unprognostic (5.08e-2)" "unprognostic (9.33e-2)" "potential prognostic unfavorable (7.34e-4)" "unprognostic (1.15e-3)" "unprognostic (9.19e-2)" "unprognostic (1.24e-1)" "unprognostic (1.11e-1)" "unprognostic (4.27e-3)" "unprognostic (2.84e-3)" "unprognostic (9.24e-3)" "unprognostic (4.87e-2)" "unprognostic (8.25e-2)" "unprognostic (3.28e-2)" "unprognostic (1.31e-2)" ENSG00000269825 ENSG00000269825 "Novel zinc finger protein" 19 52650447-52690496 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 3.3;Cone photoreceptor cells: 2.1;Erythrocyte progenitors: 1.2;Megakaryocytes: 6.2;Ocular epithelial cells: 1.8;Pancreatic duct cells: 1.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" HPA042466 Uncertain Approved "Nucleoli rim" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 40: Non-specific - Mixed function" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 3: Rhabdoid - Membrane components" "Cluster 17: Non-specific - RNA processing" "Nucleoli rim" "HPA042466: " "potential prognostic favorable (3.55e-4)" "unprognostic (1.20e-2)" "unprognostic (1.36e-2)" "unprognostic (7.41e-2)" "unprognostic (1.13e-2)" "unprognostic (1.98e-1)" "potential prognostic favorable (1.22e-5)" "unprognostic (2.91e-3)" "unprognostic (1.15e-1)" "unprognostic (5.71e-3)" "unprognostic (1.37e-1)" "unprognostic (4.73e-1)" "unprognostic (7.49e-2)" "potential prognostic unfavorable (8.53e-5)" "unprognostic (3.49e-1)" "unprognostic (7.99e-2)" "unprognostic (4.23e-1)" "unprognostic (1.11e-1)" ENSG00000270249 ENSG00000270249 "Novel protein" 7 102541501-102592444 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skeletal muscle: 2.1" "Cell type enhanced" "Detected in some" "Myonuclei: 7.1;Neuroendocrine cells: 1.3;Podocytes: 1.0;Proximal tubule cells: 1.4;Retinal bipolar cells: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" HPA046970 Uncertain Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 37: Neurons - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" Nucleoplasm "HPA046970: " "unprognostic (1.73e-2)" "unprognostic (1.24e-1)" ENSG00000270299 ENSG00000270299 "Novel protein" 20 646626-675800 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.4;Epicardial cells: 2.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" NA NA "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 7: Liver cancer - Metabolism" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" "unprognostic (2.86e-3)" ENSG00000271254 ENSG00000271254 Unmapped 4612-29626 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 67.3;Early primary spermatocytes: 192.5;Late primary spermatocytes: 113.4;Leydig cells: 40.4" "Low cell type specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050" Uncertain Approved "Golgi apparatus,Vesicles,Microtubules,Cytokinetic bridge,Primary cilium,Cytosol,Mid piece,Principal piece,End piece" Yes NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 30: White matter - Myelination" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 3: Early primary spermatocytes - Early meiosis" "Primary cilium, Cytosol" "Golgi apparatus, Vesicles, Microtubules, Cytokinetic bridge, Mid piece, Principal piece, End piece" "HPA042595: , HPA043105: , HPA043692: , HPA044023: , HPA046971: , HPA058050: " ENSG00000271810 ENSG00000271810 "Novel protein, PPM1J-RHOC readthrough" 1 112702614-112711433 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "testis: 3.6" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 1.7;Cone photoreceptor cells: 4.1;Epicardial cells: 2.3;Myonuclei: 4.6;pDCs: 2.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 61: Non-specific - Transcription" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" "unprognostic (3.13e-2)" "unprognostic (1.64e-3)" "unprognostic (2.25e-1)" "unprognostic (2.45e-2)" "unprognostic (2.68e-2)" "unprognostic (5.22e-1)" ENSG00000272104 ENSG00000272104 "Novel protein" 3 50350892-50367923 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 5 "Cardiomyocytes: 36.4;Epicardial cells: 25.0" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 60: Stomach - Digestion" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "unprognostic (3.14e-2)" "unprognostic (1.01e-2)" "potential prognostic favorable (1.25e-4)" "unprognostic (1.07e-1)" "unprognostic (1.73e-1)" "unprognostic (2.69e-2)" "unprognostic (3.67e-1)" "potential prognostic favorable (6.91e-5)" "unprognostic (5.04e-3)" "unprognostic (2.53e-3)" "unprognostic (1.99e-3)" "unprognostic (2.48e-1)" "unprognostic (5.76e-2)" "unprognostic (9.98e-2)" "unprognostic (1.02e-1)" "unprognostic (1.17e-1)" "unprognostic (3.29e-2)" "unprognostic (2.93e-1)" "unprognostic (1.38e-1)" "unprognostic (6.89e-2)" ENSG00000272297 ENSG00000272297 "Novel protein" 4 186426546-186555328 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 14 "testis: 28.3" "Group enriched" "Detected in some" 4 "Endometrial secretory cells: 20.7;Proximal tubule cells: 41.7" "Cell type enhanced" "Detected in some" "oligodendrocyte precursor cell: 4.9;upper rhombic lip: 8.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bone cancer: 4.1;Gallbladder cancer: 1.1" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 53: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 88: Proximal tubular cells - Transmembrane transport" ENSG00000272617 ENSG00000272617 "Novel protein, COG8-PDF readthrough" 16 69328644-69334871 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 31: Non-specific - Transcription" "Cluster 68: Non-specific - Cell cycle regulation" "unprognostic (2.98e-1)" "unprognostic (1.43e-2)" "unprognostic (3.67e-2)" "unprognostic (1.15e-1)" "unprognostic (8.49e-2)" "unprognostic (3.52e-1)" "unprognostic (1.17e-3)" "unprognostic (6.58e-2)" "potential prognostic favorable (4.38e-5)" "unprognostic (1.19e-1)" "unprognostic (1.74e-3)" "unprognostic (1.00e-2)" "unprognostic (4.06e-3)" "unprognostic (4.62e-3)" "unprognostic (1.65e-1)" "unprognostic (5.27e-2)" "unprognostic (1.90e-1)" "unprognostic (1.46e-1)" "unprognostic (1.06e-1)" "unprognostic (7.44e-2)" "unprognostic (2.85e-1)" "unprognostic (1.67e-1)" "unprognostic (8.49e-2)" "unprognostic (5.35e-2)" "unprognostic (4.69e-1)" "unprognostic (2.14e-1)" ENSG00000272772 ENSG00000272772 "Novel protein" 5 134157088-134225861 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 2.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA053745 Approved "Nucleoplasm,Cytokinetic bridge,Primary cilium,Centrosome,Basal body,Cytosol" Yes NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 27: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 3 "Nucleoplasm, Cytosol" "Cytokinetic bridge, Primary cilium, Centrosome, Basal body" "HPA053745: " "unprognostic (9.29e-3)" "unprognostic (2.69e-1)" "unprognostic (3.45e-1)" "unprognostic (4.53e-2)" ENSG00000272822 ENSG00000272822 "Novel protein" 12 48903503-48957365 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 2.7" "Cell type enhanced" "Detected in many" "Granulosa cells: 97.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 6.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" HPA068942 Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 27: T-cells - Unknown function" "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 103: Non-specific - Basic cellular processes" "Nucleoplasm, Nuclear bodies" "HPA068942: " "potential prognostic unfavorable (1.58e-4)" "unprognostic (1.08e-1)" "unprognostic (2.15e-1)" "unprognostic (4.98e-3)" "unprognostic (1.92e-2)" "unprognostic (4.58e-2)" "unprognostic (1.61e-2)" "unprognostic (6.06e-2)" ENSG00000272980 ENSG00000272980 "Novel protein" 6 166999336-167139138 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 7 "testis: 22.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 26.9;Early primary spermatocytes: 14.3;Early spermatids: 26.7;Innate lymphoid cells: 22.1;Late spermatids: 39.2;Retinal ganglion cells: 19.3;Rod photoreceptor cells: 26.4" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA071876 Approved Approved "Centriolar satellite,Centrosome,Basal body" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 57: Testis - Spermatogenesis" "Cluster 1: Neurons - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 9: T-cells - Adaptive immunity: Regulation" "Centrosome, Basal body" "Centriolar satellite" "HPA071876: " ENSG00000273047 ENSG00000273047 "Novel transcript, LIME1-SLC2A4RG readthrough" 20 63738270-63740398 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "liver: 7.0" "Cell type enhanced" "Detected in some" "Colonocytes: 2.4;Enteric stem cells: 2.8;Enterocytes: 3.8;Foveolar cells: 5.7;Gastric chief cells: 13.1;Hepatocytes: 3.1;Mucous neck cells: 4.7;Paneth cells: 3.9;Plasma cells: 7.1;T-cells: 3.5;Tuft cells: 11.5" "Cell type enhanced" "Detected in single" "leukocyte: 3.0" "Cancer enriched" "Detected in many" 4 "Liver Hepatocellular Carcinoma (TCGA): 23.6" "Region enhanced" "Detected in single" "white matter: 1.1" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 6.2" "Group enriched" "Detected in many" 31 "dendritic cells: 6.2;T-cells: 4.3" "Not detected" "Not detected" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 11: White matter - Signal transduction" "Cluster 18: Liver cancer - Metabolism" "Cluster 67: Plasma cells - Plasma cell differentiation" "unprognostic (4.86e-1)" "potential prognostic favorable (3.85e-4)" "unprognostic (1.31e-1)" "unprognostic (3.41e-1)" "unprognostic (1.12e-2)" ENSG00000273049 ENSG00000273049 "Novel protein, readthrough between HOXC10 and HOXC5" 12 53985845-54034888 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 4 "skeletal muscle: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 2.0" NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 3: Rhabdoid - Membrane components" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" ENSG00000273088 ENSG00000273088 "Novel protein" 1 155169409-155187272 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "epididymis: 1.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 21.5;Breast lactating cells: 27.0;Conjunctival goblet cells: 11.7;Endometrial glandular cells: 13.2;Endometrial luminal cells: 17.9;Epicardial cells: 15.9;Papillary tip epithelial cells: 12.9;Prostatic hillock cells: 11.7;Salivary basal cells: 14.9;Transitional alveolar cells: 22.6" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 1.5;Ovary Serous Cystadenocarcinoma (TCGA): 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 45: Non-specific - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" "unprognostic (1.37e-1)" "unprognostic (1.44e-1)" ENSG00000273154 ENSG00000273154 "Novel protein, ZGPAT-LIME1 readthrough" 20 63708864-63739103 "Predicted intracellular proteins, Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Kupffer cells: 1.0;Neuroendocrine cells: 1.8" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 2.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 27: Breast cancer - Unknown function" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" "unprognostic (8.92e-1)" "unprognostic (3.50e-3)" ENSG00000273155 ENSG00000273155 "Novel LIPT1-MRPL30 readthrough" 2 99154998-99195298 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Cholangiocytes: 2.0;Epididymal basal cells: 1.4;Extravillous trophoblasts: 1.0;Gastric chief cells: 2.2;Parietal cells: 1.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in some" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 31: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 15: Non-specific - Protein processing" "unprognostic (1.33e-2)" "unprognostic (1.61e-1)" ENSG00000273171 ENSG00000273171 "Novel protein, readthrough between VTN and SEBOX" 17 28364288-28368012 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 6 "liver: 1.1" "Cell type enriched" "Detected in some" 4 "Hepatocytes: 29.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" ENSG00000273217 ENSG00000273217 "Novel protein" 5 131425891-131796983 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Early spermatids: 7.3;Late spermatids: 7.5;Myonuclei: 5.6;Neutrophil progenitors: 7.1;Neutrophils: 16.8;Thymocytes: 5.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Lineage enriched" "Detected in many" 4 "T-cells: 8.2" "Not detected" "Not detected" "HPA037982, HPA037983" Uncertain Approved Centrosome,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" Cytosol Centrosome "HPA037982: , HPA037983: " ENSG00000273291 ENSG00000273291 "Novel protein" 3 42809446-43055871 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 8 "testis: 1.0" "Cell type enhanced" "Detected in many" "Oligodendrocyte progenitor cells: 15.7;Pituicytes/FSCs: 12.3;Pituitary stem cells: 12.6;Retinal ganglion cells: 15.5;Sertoli cells: 15.4;Syncytiotrophoblasts: 12.5" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 7: Non-specific - Transcription" "unprognostic (1.18e-1)" ENSG00000273554 ENSG00000273554 Unmapped 1139577-1147868 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "skin 1: 1.5;testis: 4.3" "Group enriched" "Detected in some" 17 "Early spermatids: 6.6;Late spermatids: 6.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" NA NA "Cluster 47: Testis - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" ENSG00000273748 ENSG00000273748 Unmapped 54224-83311 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA049380 Approved NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 22: Epididymis - Mixed function" "Cluster 34: Non-specific - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" "HPA049380: " ENSG00000274175 ENSG00000274175 Unmapped 17234-19833 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 29 "epididymis: 5.7;testis: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047832, HPA060916" Uncertain "Centriolar satellite" NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Centriolar satellite" "HPA047832: , HPA060916: " ENSG00000274792 ENSG00000274792 Unmapped 386278-387620 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA057442 Uncertain Uncertain Centrosome NA NA Centrosome "HPA057442: " ENSG00000274944 ENSG00000274944 "Novel protein" 1 38864501-38881617 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "testis: 4.7" "Cell type enhanced" "Detected in some" "Adipocytes: 1.2;Cardiomyocytes: 1.5;Early spermatids: 3.9;Epicardial cells: 2.3;Late primary spermatocytes: 7.9;Thymocytes: 1.7" "Cell type enhanced" "Detected in single" "ependymal cell: 1.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 3.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "HPA041188, HPA078331" Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 37: Non-specific - mRNA processing" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" Nucleoplasm Mitochondria "HPA041188: , HPA078331: " "unprognostic (3.98e-2)" "unprognostic (1.40e-2)" "unprognostic (2.55e-3)" "unprognostic (3.58e-1)" "unprognostic (8.51e-2)" "unprognostic (2.51e-1)" "unprognostic (4.60e-3)" "unprognostic (4.42e-1)" "potential prognostic unfavorable (3.97e-4)" "unprognostic (9.62e-2)" "unprognostic (1.19e-2)" "unprognostic (3.16e-2)" "potential prognostic favorable (2.32e-4)" "unprognostic (2.95e-3)" "unprognostic (1.26e-1)" "unprognostic (1.21e-1)" "unprognostic (9.02e-3)" "unprognostic (2.50e-2)" "potential prognostic unfavorable (2.23e-4)" "unprognostic (5.08e-2)" "unprognostic (4.04e-3)" ENSG00000275063 ENSG00000275063 P0DP08 Unmapped 41444-41876 "Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 583.6;lymphoid tissue: 715.9;urinary bladder: 406.8" "Cell type enriched" "Detected in some" 9 "Plasma cells: 30.7" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebral cortex: 2.2" "Group enriched" "Detected in some" 368 "memory B-cell: 404.4;naive B-cell: 260.3" "Lineage enriched" "Detected in single" 447 "B-cells: 404.4" "Cancer enriched" "Detected in some" 4 "lymphoma: 47.9" "Secreted to blood" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 13: Non-specific - Mixed function" "Cluster 78: Plasma cells - Antibody production & ER-stress response" ENSG00000275163 ENSG00000275163 "Potassium large conductance calcium-activated channel, subfamily M, beta member 2 (KCNMB2-IT1 - KCNMB2 readthrough transcript)" 3 178419123-178843300 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 7 "fallopian tube: 5.2;kidney: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 1.2;Rhabdoid: 3.0" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" ENSG00000275249 ENSG00000275249 Unmapped 372322-373405 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA058889 Uncertain NA NA "HPA058889: " ENSG00000275674 ENSG00000275674 "Novel protein" 15 90266317-90314499 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "intestine: 1.1;pancreas: 1.1" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 60: Stomach - Digestion" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 7: Liver cancer - Metabolism" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" ENSG00000275740 ENSG00000275740 "Novel readthrough transcript" 5 146203550-146339251 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "testis: 6.3" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 20.9;Thymocytes: 26.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA035944, HPA036422" Approved Approved "Nuclear speckles" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 16: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 51: Secretory epithelial cells - Mixed function" "Nuclear speckles" "HPA035944: , HPA036422: " "unprognostic (2.46e-1)" "unprognostic (4.12e-1)" "unprognostic (1.04e-1)" "unprognostic (5.93e-2)" "unprognostic (1.36e-2)" "unprognostic (5.15e-3)" "unprognostic (6.40e-2)" "unprognostic (1.97e-1)" "unprognostic (1.56e-1)" "unprognostic (2.10e-1)" "unprognostic (9.99e-2)" "unprognostic (3.99e-2)" "unprognostic (4.68e-2)" ENSG00000275778 ENSG00000275778 "PRH1-PRR4 readthrough" 12 10845849-11171600 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 4 "Late spermatids: 15.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" HPA042133 Uncertain NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 64: Non-specific - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" "HPA042133: " ENSG00000275869 ENSG00000275869 Unmapped 933862-936467 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "testis: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047832, HPA060916" Approved "Centriolar satellite" NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 3: Early primary spermatocytes - Early meiosis" "Centriolar satellite" "HPA047832: , HPA060916: " ENSG00000276017 ENSG00000276017 Unmapped 72411-74814 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 67 "testis: 10.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 105: Non-specific - Mixed function" ENSG00000276256 ENSG00000276256 Unmapped 42939-49164 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 23.1;Bergmann glia: 31.1;Brain excitatory neurons: 7.3;Distal convoluted tubule cells: 18.7;Loop of henle epithelial cells: 12.9;Oligodendrocyte progenitor cells: 46.3;Oligodendrocytes: 8.9;Other brain neurons: 8.0;Papillary tip epithelial cells: 9.8;Podocytes: 8.5;Proximal tubule cells: 17.4;Renal collecting duct intercalated cells: 10.7;Renal collecting duct principal cells: 13.1;Renal connecting tubule cells: 29.1" "Cell type enhanced" "Detected in many" "oligodendrocyte precursor cell: 52.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 7.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 44: Non-specific - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" ENSG00000276302 ENSG00000276302 "Novel protein" 6 28267121-28281580 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 3.1;Brain inhibitory neurons: 3.0;Cardiomyocytes: 4.5;Choroid plexus epithelial cells: 3.9;Cone photoreceptor cells: 8.3;Myonuclei: 3.0;Oligodendrocytes: 3.8;Podocytes: 3.1;Thymocytes: 3.4" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 34: Non-specific - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" ENSG00000276345 ENSG00000276345 Unmapped 2585-11802 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "choroid plexus: 33.5" "Cell type enhanced" "Detected in many" "Enteric transient amplifying cells: 19.3;Enterocytes: 60.7;Extravillous trophoblasts: 38.5;Gastric chief cells: 30.6;Kupffer cells: 28.7;Mucous neck cells: 15.7;Paneth cells: 58.0;Parietal cells: 44.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" HPA050406 Uncertain Approved "Nucleoli fibrillar center,Mitochondria" NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 35: RS4;11 - Unknown function" "Cluster 67: Plasma cells - Plasma cell differentiation" "Nucleoli fibrillar center, Mitochondria" "HPA050406: " ENSG00000276760 ENSG00000276760 Unmapped 136160-167571 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA ENSG00000277400 ENSG00000277400 Q8WZ33 Unmapped 53590-115018 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 20 "Astrocytes: 77.3;Bergmann glia: 90.4;Brain excitatory neurons: 52.6;Brain inhibitory neurons: 75.3;Choroid plexus epithelial cells: 191.8;Ependymal cells: 78.4;Microglia: 116.3;Oligodendrocyte progenitor cells: 88.7;Oligodendrocytes: 126.8;Other brain neurons: 58.0" "Low cell type specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 6: Non-specific - Immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 22: Non-specific - Basic cellular functions" ENSG00000277475 ENSG00000277475 Unmapped 31698-32528 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "pancreas: 7.2;testis: 13.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 12 "eosinophil: 9.1" "Lineage enriched" "Detected in single" 12 "granulocytes: 9.1" "Low cancer specificity" "Detected in many" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 8: Pancreas - Proteolysis" "Cluster 1: Neurons - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" ENSG00000277535 ENSG00000277535 "Novel cancer/testis antigen family protein" X 119072993-119076765 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Tissue enriched" "Detected in single" 43 "testis: 4.2" "Cell type enriched" "Detected in some" 20 "Early primary spermatocytes: 190.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Spermatocytes" HPA042483 Supported Approved Nucleoli NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 3: Early primary spermatocytes - Early meiosis" Nucleoli "HPA042483: " ENSG00000277630 ENSG00000277630 Unmapped 108007-139659 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 33 "testis: 3.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" ENSG00000277639 ENSG00000277639 "Novel protein" 16 53035690-53052897 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Tissue enriched" "Detected in many" 4 "choroid plexus: 163.8" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 102.7;Endometrial ciliated cells: 302.8;Epididymal efferent duct ciliated cells: 187.2;Fallopian secretory cells: 261.6;Fallopian tube ciliated cells: 486.5;Respiratory ciliated cells: 603.3;Respiratory deuterosomal cells: 100.6;Tuft cells: 161.4" "Group enriched" "Detected in some" 17 "choroid plexus epithelial cell: 91.0;ependymal cell: 94.2" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 27.8" "Region enriched" "Detected in many" 8 "choroid plexus: 117.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Esophageal cancer: 8.7;Rhabdoid: 9.9" "Lung - Respiratory ciliated cells, Skin - Eccrine sweat gland cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 107: Ciliated cells - Cilia assembly & function" "unprognostic (3.63e-2)" "unprognostic (3.04e-2)" "unprognostic (5.19e-3)" "unprognostic (9.83e-2)" "unprognostic (2.10e-1)" "unprognostic (6.48e-2)" "unprognostic (3.45e-2)" "unprognostic (2.21e-1)" "unprognostic (2.64e-1)" "unprognostic (8.32e-2)" "unprognostic (9.27e-2)" "unprognostic (3.20e-1)" "unprognostic (1.58e-1)" "unprognostic (1.43e-1)" "unprognostic (6.75e-3)" "unprognostic (4.04e-2)" "unprognostic (1.03e-1)" "unprognostic (4.11e-1)" "unprognostic (1.55e-1)" "unprognostic (1.23e-1)" "unprognostic (1.79e-1)" ENSG00000277836 ENSG00000277836 Unmapped 1270984-1271271 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "intestine: 89.0;lymphoid tissue: 119.9;salivary gland: 52.4;stomach 1: 64.3;urinary bladder: 37.7" "Cell type enriched" "Detected in single" 11 "Plasma cells: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 133 "memory B-cell: 17.7;naive B-cell: 8.7" "Lineage enriched" "Detected in single" 178 "B-cells: 17.7" "Cancer enriched" "Detected in some" 6 "lymphoma: 64.9" NA NA "Cluster 18: Non-specific - Translation" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 44: Plasma cells - Antibody production & secretion" ENSG00000277856 ENSG00000277856 Unmapped 26241-26534 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 93.5;lymphoid tissue: 209.1;stomach 1: 87.7" "Cell type enriched" "Detected in single" 74 "Plasma cells: 27.7" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 311 "memory B-cell: 27.5;naive B-cell: 34.5" "Lineage enriched" "Detected in single" 345 "B-cells: 34.5" "Group enriched" "Detected in some" 11 "Leukemia: 6.1;lymphoma: 12.9" NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 22: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 44: Plasma cells - Antibody production & secretion" ENSG00000278263 ENSG00000278263 "Novel protein, identical to IGHV4-4" 15 21742364-21742799 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 48.8;lymphoid tissue: 53.9;urinary bladder: 91.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 30 "memory B-cell: 24.1;naive B-cell: 7.8" "Lineage enriched" "Detected in single" 45 "B-cells: 24.1" "Not detected" "Not detected" "Adipose visceral - Plasma cells, Breast - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Prostate - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 46: Lymphoma - Humoral immune response" "unprognostic (2.55e-1)" "unprognostic (1.12e-1)" "unprognostic (2.31e-1)" "unprognostic (1.02e-1)" "unprognostic (1.60e-1)" "potential prognostic favorable (3.94e-4)" "unprognostic (1.76e-2)" "unprognostic (2.10e-1)" "unprognostic (9.69e-2)" "unprognostic (4.27e-2)" "unprognostic (1.72e-1)" "unprognostic (3.37e-2)" "unprognostic (2.31e-1)" "unprognostic (7.20e-2)" "unprognostic (6.35e-2)" "unprognostic (1.80e-1)" "unprognostic (2.39e-2)" "unprognostic (2.28e-1)" "unprognostic (3.62e-1)" "unprognostic (5.37e-2)" "unprognostic (2.27e-1)" "unprognostic (1.79e-1)" "unprognostic (1.15e-1)" ENSG00000278384 ENSG00000278384 Unmapped 51867-54893 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "retina: 5.1" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 5.9;Lactotrophs: 5.5;Myonuclei: 6.0;Pituicytes/FSCs: 5.7;Podocytes: 7.2;Proximal tubule cells: 6.8;Renal collecting duct intercalated cells: 7.7;Sertoli cells: 7.0" "Low cell type specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 6: Non-specific - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 88: Proximal tubular cells - Transmembrane transport" ENSG00000278633 ENSG00000278633 Unmapped 10598-13001 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 303 "testis: 32.9" "Cell type enhanced" "Detected in some" "Early primary spermatocytes: 1.4;Late primary spermatocytes: 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" ENSG00000278646 ENSG00000278646 "Novel protein similar to cancer/testis antigen family 47, member A12 (CT47A12)" X 120877496-120878924 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 8 "testis: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Liver Hepatocellular Carcinoma (TCGA): 1.8;Testicular Germ Cell Tumor (TCGA): 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA042483 Supported Uncertain Nucleoli NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 20: Myeloma - Immune response" Nucleoli "HPA042483: " "unprognostic (5.87e-1)" "unprognostic (3.22e-2)" ENSG00000278704 ENSG00000278704 Unmapped 56140-58376 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 1.6;Epicardial cells: 2.3;Sertoli cells: 1.1;Vascular endothelial cells: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" NA NA "Cluster 49: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" ENSG00000278817 ENSG00000278817 Unmapped 131494-137392 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "choroid plexus: 75.0;heart muscle: 51.8;skeletal muscle: 107.0;tongue: 125.6" "Cell type enriched" "Detected in many" 5 "Late spermatids: 1092.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 52: Non-specific - Cellular respiration" "Cluster 44: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" ENSG00000279073 ENSG00000279073 "Novel protein" 9 137031241-137040436 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 10.6;Brain excitatory neurons: 10.5;Brain inhibitory neurons: 9.2;Gastric chief cells: 8.7;Goblet cells: 26.3;Macrophages: 9.0;Neuroendocrine cells: 8.9;Other brain neurons: 10.1;Vascular endothelial cells: 14.8" "Low cell type specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in some" 4 "Leukemia: 7.3" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 15: Non-specific - Transcription" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" ENSG00000279983 ENSG00000279983 "Novel protein" 5 141223372-141245861 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "epididymis: 1.6" "Cell type enhanced" "Detected in many" "Corticotrophs: 21.9;Fibro-adipogenic progenitors: 10.0;Lactotrophs: 18.7;Myosatellite cells: 7.7;Pituicytes/FSCs: 12.4;Pituitary stem cells: 12.9;Podocytes: 8.0;Retinal bipolar cells: 12.7;Retinal pigment epithelial cells: 12.8;Somatotrophs: 10.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 15: Kidney cancer - Membrane components" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" ENSG00000280571 ENSG00000280571 "Novel protein" 3 42705756-42804518 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 9 "retina: 7.1" "Cell type enhanced" "Detected in many" "Colonocytes: 16.2" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047429 Approved "Nucleoplasm,Centriolar satellite,Basal body,Cytosol" NA NA "Cluster 42: Retina - Visual perception" "Cluster 11: White matter - Signal transduction" "Cluster 1: Neuronal - Visual perception" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" "Centriolar satellite" "Nucleoplasm, Basal body, Cytosol" "HPA047429: " ENSG00000280778 ENSG00000280778 "Novel protein, lncRNA-POLR3GL readthrough" 1 145927258-145977811 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Adipocytes: 2.7;Cardiomyocytes: 2.8;Cone photoreceptor cells: 2.1;Epicardial cells: 4.5;Late primary spermatocytes: 1.4;Late spermatids: 1.5;Medullary thymic epithelial cells: 2.4;Myonuclei: 1.2;Thymic myoid cells: 2.7" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 7.6" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 10 "neutrophil: 1.8" "Lineage enriched" "Detected in single" 10 "granulocytes: 1.8" "Not detected" "Not detected" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" ENSG00000281039 ENSG00000281039 "Novel protein" 7 30497077-30550761 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 27.1;Distal convoluted tubule cells: 55.8;Epicardial cells: 27.3;Loop of henle epithelial cells: 45.1;Papillary tip epithelial cells: 27.9;Podocytes: 68.9;Proximal tubule cells: 52.3;Renal collecting duct intercalated cells: 37.1;Renal collecting duct principal cells: 27.1;Renal connecting tubule cells: 41.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" HPA020735 Uncertain NA NA "Cluster 40: Non-specific - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 105: Non-specific - Mixed function" "HPA020735: " "unprognostic (1.89e-2)" "unprognostic (1.29e-1)" "unprognostic (8.10e-2)" "unprognostic (7.03e-3)" "unprognostic (9.01e-2)" "unprognostic (1.33e-1)" "unprognostic (1.93e-2)" "unprognostic (8.94e-2)" "potential prognostic unfavorable (2.02e-5)" "unprognostic (2.88e-1)" "unprognostic (3.58e-2)" "unprognostic (2.21e-1)" "unprognostic (1.61e-2)" "unprognostic (2.00e-1)" "unprognostic (1.79e-1)" "unprognostic (1.11e-1)" "unprognostic (9.03e-2)" "potential prognostic favorable (6.59e-5)" "unprognostic (5.71e-2)" "unprognostic (8.07e-2)" "unprognostic (2.32e-1)" "unprognostic (1.17e-1)" "unprognostic (2.68e-1)" "unprognostic (3.92e-1)" "unprognostic (7.10e-2)" "unprognostic (2.15e-2)" ENSG00000281179 ENSG00000281179 "Novel gene identicle to IGHV1OR15-1" 15 21717808-21718245 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 73.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "memory B-cell: 94.7;naive B-cell: 112.0" "Group enriched" "Detected in many" 18 "B-cells: 112.0;T-cells: 61.1" "Group enriched" "Detected in some" 23 "Leukemia: 7.2;lymphoma: 3.2;Myeloma: 3.5" "Breast - Plasma cells, Minor Salivary Gland - Plasma cells, Stomach - Plasma cells" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "potential prognostic favorable (7.49e-4)" "unprognostic (5.65e-2)" "unprognostic (1.89e-1)" "unprognostic (2.57e-2)" "potential prognostic favorable (1.15e-4)" "unprognostic (1.77e-2)" "unprognostic (8.41e-2)" "unprognostic (1.20e-2)" "unprognostic (3.47e-1)" "unprognostic (2.03e-2)" "unprognostic (1.16e-1)" "unprognostic (1.09e-1)" "unprognostic (2.03e-1)" "unprognostic (7.18e-2)" "unprognostic (1.96e-1)" "unprognostic (7.79e-2)" "unprognostic (3.66e-1)" "unprognostic (9.38e-2)" ENSG00000281613 ENSG00000281613 "Novel ret finger protein-like 4B" 6 112236806-112350094 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 12 "testis: 4.4" "Cell type enhanced" "Detected in some" "Early spermatids: 4.3;Extravillous trophoblasts: 5.4;Gastric chief cells: 1.1;Late spermatids: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA059324 Uncertain NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 5: Rhabdoid - Unknown function" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" "HPA059324: " ENSG00000282218 ENSG00000282218 "Novel protein, GOPC-ROS1 readthrough" 6 117318211-117573571 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "Adipocytes: 28.7;Alveolar cells type 2: 57.3;Cardiomyocytes: 87.7;Early spermatids: 22.7;Epicardial cells: 79.6;Late spermatids: 70.2;Myonuclei: 28.8;Pericytes: 96.7" "Cell type enhanced" "Detected in many" "pericyte: 12.2" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "cerebral cortex: 1.2;pons: 1.3;white matter: 1.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA019477 Uncertain Approved "Golgi apparatus,Calyx,Connecting piece,Mid piece,Principal piece" NA NA "Cluster 53: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "Golgi apparatus, Calyx, Mid piece" "Connecting piece, Principal piece" "HPA019477: " ENSG00000282278 ENSG00000282278 "Novel FIP1L1-PDGFRA fusion protein" 4 53377839-54295272 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "tongue: 2.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 488.6;Endometrial glandular cells: 434.0;Epicardial cells: 991.5;Fibro-adipogenic progenitors: 252.4;Loop of henle epithelial cells: 512.8;Myonuclei: 285.4" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "head and neck cancer: 4.5;Rhabdoid: 4.9;thyroid cancer: 6.2" "HPA058202, HPA079225, HPA079228" Supported Nucleoplasm NA NA "Cluster 61: Non-specific - Transcription" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 61: BICR 18 - Protein kinases" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" Nucleoplasm "HPA058202: , HPA079225: , HPA079228: " "unprognostic (4.67e-2)" "unprognostic (5.90e-3)" "unprognostic (1.88e-1)" "unprognostic (2.84e-2)" ENSG00000282804 ENSG00000282804 "Novel protein" 6 24797373-24809798 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 13 "Neutrophils: 201.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 59: Leukemia - T-cell receptor" "Cluster 24: Neutrophils - Innate immunity signal integration" ENSG00000282936 ENSG00000282936 "Novel protein" 17 6628619-6640456 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Spermatocytes" "Low region specificity" "Detected in all" NA NA "Cluster 65: Brain - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 42: Non-specific - Unknown function" ENSG00000282988 ENSG00000282988 "Novel protein" 6 26195595-26199293 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "esophagus: 4.2;prostate: 4.1" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 88.4;Colonocytes: 87.7;Erythrocyte progenitors: 66.1;Hematopoietic stem cells: 119.4;Megakaryocyte progenitors: 82.7;Megakaryocyte-Erythroid progenitors: 100.2;Monocyte progenitors: 79.0;Platelets: 89.0;Prostatic club cells: 74.3;Thymocytes: 64.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 17.0;neutrophil: 30.6" "Lineage enriched" "Detected in many" 6 "granulocytes: 30.6" "Low cancer specificity" "Detected in many" HPA041189 Uncertain Approved Nucleoplasm NA Yes "Cluster 35: Neutrophils - Protein binding" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 55: Non-specific - Transcription" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 65: Non-specific - Cell growth & division" Nucleoplasm "HPA041189: " "unprognostic (5.28e-3)" "unprognostic (3.44e-2)" "potential prognostic favorable (5.77e-4)" "unprognostic (1.23e-1)" "unprognostic (1.17e-1)" "unprognostic (3.29e-2)" "unprognostic (1.08e-2)" "unprognostic (2.00e-1)" "unprognostic (1.42e-1)" "unprognostic (5.38e-2)" "unprognostic (7.38e-2)" "unprognostic (2.42e-1)" "unprognostic (6.97e-2)" "unprognostic (4.54e-1)" "unprognostic (8.01e-2)" ENSG00000283128 ENSG00000283128 "Novel protein" 7 155474256-155644406 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Bergmann glia: 4.0;Early spermatids: 5.3;Epididymal efferent duct absorptive cells: 5.3;Late primary spermatocytes: 4.4;Late spermatids: 4.9;Myonuclei: 5.5;Neutrophils: 4.4;Thymic myoid cells: 8.2" "Cell type enhanced" "Detected in some" "Bergmann glia: 5.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047400 Uncertain NA NA "Cluster 70: DU4475 - Unknown function" "Cluster 37: Neutrophil progenitors - Granulopoiesis" "HPA047400: " ENSG00000283149 ENSG00000283149 "Novel protein" 3 186581995-186597103 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 4.8;Erythrocyte progenitors: 5.1;Loop of henle epithelial cells: 5.7;Papillary tip epithelial cells: 8.2;Renal collecting duct principal cells: 6.9;Retinal pigment epithelial cells: 4.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA010814 Uncertain Supported "Endoplasmic reticulum" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 70: Non-specific - Protein processing" "Cluster 16: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" "Endoplasmic reticulum" "HPA010814: " "unprognostic (3.25e-1)" "unprognostic (1.43e-1)" "unprognostic (1.88e-1)" "unprognostic (2.40e-1)" "unprognostic (7.92e-2)" "unprognostic (1.22e-1)" "unprognostic (1.26e-3)" "unprognostic (2.84e-3)" "potential prognostic unfavorable (2.85e-5)" "unprognostic (9.40e-3)" "unprognostic (3.32e-2)" "unprognostic (3.62e-2)" "unprognostic (1.25e-2)" "unprognostic (1.54e-1)" "unprognostic (2.23e-2)" "unprognostic (5.56e-3)" "unprognostic (1.46e-3)" "unprognostic (2.26e-3)" "unprognostic (3.03e-2)" "unprognostic (2.48e-1)" "unprognostic (3.33e-3)" "unprognostic (7.93e-2)" "unprognostic (1.05e-1)" "unprognostic (3.23e-2)" "unprognostic (1.54e-1)" "unprognostic (2.35e-2)" ENSG00000283189 ENSG00000283189 "Novel protein" 3 49416777-49429314 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 59: Leukemia - T-cell receptor" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" ENSG00000283201 ENSG00000283201 "Zinc finger protein 724" 19 23222755-23274221 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Epididymal basal cells: 19.0;Epididymal clear cells: 22.5;Proximal tubule cells: 13.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 22: Epididymis - Mixed function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 35: Neurons - Synaptic function & neurogenesis" 4 "unprognostic (4.69e-2)" "unprognostic (1.65e-1)" "unprognostic (1.66e-1)" "unprognostic (2.39e-2)" "unprognostic (4.10e-2)" "unprognostic (7.42e-2)" "potential prognostic favorable (4.59e-7)" "unprognostic (1.75e-3)" "unprognostic (1.33e-1)" "unprognostic (4.11e-3)" "unprognostic (2.13e-2)" "unprognostic (1.17e-1)" "unprognostic (3.72e-2)" "unprognostic (3.60e-1)" "unprognostic (7.03e-2)" "potential prognostic favorable (4.01e-5)" "unprognostic (3.01e-1)" "unprognostic (1.39e-1)" "unprognostic (7.87e-2)" "unprognostic (1.92e-1)" "unprognostic (1.12e-1)" ENSG00000283205 ENSG00000283205 "Novel protein" 9 87956214-87956883 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 49 "testis: 5.7" "Group enriched" "Detected in some" 19 "Early spermatids: 73.6;Late primary spermatocytes: 48.6;Late spermatids: 82.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" ENSG00000283208 ENSG00000283208 "Novel protein" 13 76992078-77129589 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "bone marrow: 4.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 59.2;Epicardial cells: 70.5" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Prostate Adenocarcinoma (TCGA): 2.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 15: Bone marrow - Innate immune response" "Cluster 9: Non-specific - Receptor signaling" "Cluster 19: Non-specific - Unknown function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "unprognostic (8.15e-2)" "unprognostic (9.76e-2)" "unprognostic (3.95e-2)" "unprognostic (2.27e-1)" ENSG00000283321 ENSG00000283321 "Novel protein" 7 17299295-17467234 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 6 "cervix: 7.9;urinary bladder: 14.3" "Cell type enhanced" "Detected in many" "cDC: 12.8;Conjunctival goblet cells: 19.4;Endometrial glandular cells: 17.0;Endometrial luminal cells: 11.7;Innate lymphoid cells: 11.4;Mast cells: 11.6;Schwann cells: 16.8;Urothelial cells: 25.7" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 15.8;Kidney Renal Papillary Cell Carcinoma (TCGA): 9.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Kidney cancer: 8.6" HPA029722 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 13: Lung - Secretion" "Cluster 15: Kidney cancer - Membrane components" "Cluster 69: Urothelial cells - Basic cellular functions" "Nucleoplasm, Cytosol" "HPA029722: " "unprognostic (8.62e-2)" "unprognostic (2.91e-3)" "unprognostic (1.26e-1)" "unprognostic (2.10e-1)" "unprognostic (1.28e-1)" "unprognostic (3.15e-2)" "unprognostic (1.64e-2)" "unprognostic (1.29e-1)" "unprognostic (4.13e-1)" "unprognostic (3.19e-1)" "unprognostic (1.83e-1)" "unprognostic (5.32e-2)" "unprognostic (5.80e-2)" ENSG00000283536 ENSG00000283536 "Novel protein" 12 53241900-53242722 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 46 "retina: 16.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 42: Retina - Visual perception" "Cluster 1: Neuronal - Visual perception" "Cluster 79: Photoreceptor cells - Phototransduction" ENSG00000283599 ENSG00000283599 "Novel protein similar to CXorf49" X 71667542-71671527 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 29 "testis: 8.1" "Group enriched" "Detected in some" 4 "Differentiating spermatogonia: 6.2;Early primary spermatocytes: 18.5;Late primary spermatocytes: 4.6;Undifferentiated spermatogonia: 11.4" "Cell type enhanced" "Detected in some" "amygdala excitatory: 2.7;upper-layer intratelencephalic: 5.8" "Cancer enhanced" "Detected in some" "Liver Hepatocellular Carcinoma (TCGA): 1.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "thyroid cancer: 1.7" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 106: Spermatogonia - Spermatogonial differentiation" "unprognostic (3.89e-1)" "unprognostic (7.60e-3)" "unprognostic (4.94e-1)" ENSG00000283761 ENSG00000283761 "Novel protein" 1 99970011-100083321 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Adipocytes: 3.9;Cardiomyocytes: 17.9;Epicardial cells: 6.8;Late spermatids: 4.7;Thymocytes: 3.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 6.0" HPA073681 Approved Vesicles NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 21: Non-specific - Metabolism" "Cluster 37: Non-specific - mRNA processing" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" Vesicles "HPA073681: " "unprognostic (3.26e-3)" "unprognostic (3.60e-2)" "unprognostic (6.08e-2)" ENSG00000283765 ENSG00000283765 "Novel protein" 3 183815568-183884889 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 16.6" "Group enriched" "Detected in some" 4 "Early spermatids: 3.3;Epicardial cells: 2.3;Late primary spermatocytes: 2.0;Late spermatids: 4.1;Neuroendocrine cells: 1.2;Retinal ganglion cells: 3.9" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 4.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" HPA019545 Uncertain Approved Mitochondria NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 6: Non-specific - Immune response" "Cluster 63: Non-specific - Protein processing" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" Mitochondria "HPA019545: " "unprognostic (1.44e-1)" "unprognostic (1.15e-1)" "unprognostic (5.94e-2)" "potential prognostic unfavorable (4.89e-4)" "unprognostic (2.21e-2)" ENSG00000283782 ENSG00000283782 "Novel protein" 5 132410832-132646079 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 98.3;Epicardial cells: 368.4;Podocytes: 221.2;Renal connecting tubule cells: 110.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" HPA052291 Approved Approved Nucleoplasm NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 25: Non-specific - Transcription" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 105: Non-specific - Mixed function" Nucleoplasm "HPA052291: " "unprognostic (9.00e-2)" "unprognostic (7.50e-2)" "unprognostic (1.92e-2)" "unprognostic (6.22e-2)" "unprognostic (9.87e-3)" "unprognostic (2.75e-1)" "unprognostic (6.32e-2)" "unprognostic (2.46e-1)" "validated prognostic favorable (7.95e-6)" "validated prognostic favorable (4.56e-4)" "unprognostic (1.06e-1)" "unprognostic (1.34e-1)" "unprognostic (9.69e-2)" "unprognostic (2.74e-1)" "unprognostic (1.23e-1)" "unprognostic (5.11e-1)" "unprognostic (9.62e-2)" "unprognostic (2.17e-1)" "unprognostic (5.00e-2)" "unprognostic (1.12e-2)" "unprognostic (3.40e-2)" "unprognostic (3.47e-2)" "unprognostic (5.90e-2)" "unprognostic (2.14e-1)" "unprognostic (2.51e-2)" "unprognostic (1.28e-1)" ENSG00000283809 ENSG00000283809 "Novel protein" 22 18906238-18947732 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bergmann glia: 1.8;Cardiomyocytes: 3.4;Distal convoluted tubule cells: 2.7;Loop of henle epithelial cells: 5.6;Medullary thymic epithelial cells: 2.4;Papillary tip epithelial cells: 2.7;Podocytes: 1.5;Proximal tubule cells: 6.0;Renal collecting duct intercalated cells: 1.6;Renal connecting tubule cells: 2.1" "Cell type enhanced" "Detected in single" "Bergmann glia: 1.9" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 181.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "testis cancer: 48.3" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 48: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 105: Non-specific - Mixed function" "unprognostic (1.13e-1)" "unprognostic (5.24e-2)" "unprognostic (7.12e-3)" "unprognostic (9.73e-3)" "unprognostic (7.50e-2)" "unprognostic (1.30e-2)" "unprognostic (3.06e-1)" "potential prognostic unfavorable (6.95e-5)" "unprognostic (1.08e-3)" "unprognostic (1.21e-1)" "unprognostic (6.76e-2)" "potential prognostic unfavorable (6.78e-6)" "unprognostic (1.38e-1)" "unprognostic (5.77e-2)" "unprognostic (2.55e-3)" "unprognostic (9.09e-3)" "unprognostic (6.14e-2)" "unprognostic (2.92e-2)" "unprognostic (4.02e-1)" "unprognostic (2.87e-1)" "unprognostic (1.58e-1)" "unprognostic (7.58e-2)" "unprognostic (5.98e-2)" "unprognostic (1.99e-1)" "unprognostic (1.76e-2)" "unprognostic (3.81e-2)" ENSG00000283886 ENSG00000283886 Q8NFD4 9 39816599-39874562 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 3.4;Bergmann glia: 2.8;Brain excitatory neurons: 5.9;Brain inhibitory neurons: 6.9;Choroid plexus epithelial cells: 3.0;Ependymal cells: 2.7;Microglia: 1.6;Oligodendrocyte progenitor cells: 4.9;Oligodendrocytes: 5.5;Other brain neurons: 6.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA021733 Approved Nucleoplasm,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 61: Non-specific - Transcription" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 109: Neurons - Neuronal signaling" Nucleoplasm Cytosol "HPA021733: " "unprognostic (4.65e-2)" "unprognostic (6.60e-2)" "unprognostic (3.89e-2)" "unprognostic (2.31e-1)" "unprognostic (9.19e-2)" "unprognostic (1.12e-1)" "unprognostic (2.59e-2)" "unprognostic (5.94e-2)" "unprognostic (2.50e-1)" "unprognostic (3.39e-1)" "unprognostic (1.43e-1)" "unprognostic (4.21e-2)" "unprognostic (5.98e-3)" "unprognostic (3.46e-1)" "unprognostic (2.14e-1)" "unprognostic (1.14e-2)" "unprognostic (6.24e-2)" "unprognostic (3.20e-1)" "unprognostic (1.62e-1)" "unprognostic (1.31e-1)" ENSG00000283952 ENSG00000283952 "Novel protein" 1 211082872-211188533 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 64: Connective tissue cells - ECM organization" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" ENSG00000284057 ENSG00000284057 "Novel protein, C11orf54-MED17 readthrough" 11 93741664-93812378 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 8.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 47.6;Myonuclei: 16.9;Proximal tubule cells: 14.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in some" "HPA040511, HPA046619" Approved Approved "Nuclear speckles,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" "Nuclear speckles" Cytosol "HPA040511: , HPA046619: " "unprognostic (6.24e-2)" "validated prognostic favorable (1.28e-10)" "validated prognostic favorable (5.36e-5)" "unprognostic (9.63e-2)" "unprognostic (3.44e-1)" "unprognostic (1.11e-1)" "unprognostic (5.35e-2)" "unprognostic (1.76e-1)" ENSG00000284188 ENSG00000284188 "Novel protein" 1 244729701-244731015 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 11 "testis: 4.7" "Group enriched" "Detected in some" 4 "Early spermatids: 196.2;Late primary spermatocytes: 108.4" "Cell type enhanced" "Detected in some" "ependymal cell: 6.5" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 33: Neurons - Mixed function" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" ENSG00000284209 ENSG00000284209 "Novel protein similar to cyclin Y CCNY" 16 34351499-34381110 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 4 "bone marrow: 1.1;testis: 3.3" "Group enriched" "Detected in some" 4 "Early spermatids: 4.1;Late spermatids: 10.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" NA NA "Cluster 44: Bone marrow - Nuclear processes" "Cluster 48: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" ENSG00000284292 ENSG00000284292 "Novel protein, ARPC1A and ARPC1B readthrough" 7 99325879-99394653 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "Parietal cells: 12.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" HPA004334 Uncertain Approved "Cell Junctions,Cytosol" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 45: Non-specific - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 103: Non-specific - Basic cellular processes" 8 "Cell Junctions" Cytosol "HPA004334: " "unprognostic (5.80e-3)" "unprognostic (2.50e-2)" "unprognostic (6.07e-2)" "unprognostic (4.69e-3)" "potential prognostic unfavorable (6.37e-4)" "unprognostic (2.77e-1)" "unprognostic (1.77e-1)" "unprognostic (6.33e-2)" "unprognostic (1.93e-2)" "unprognostic (9.82e-2)" "unprognostic (1.61e-1)" "unprognostic (6.06e-1)" "unprognostic (3.36e-1)" ENSG00000284512 ENSG00000284512 "Novel protein" 16 81022316-81096284 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 6.1" "Cell type enhanced" "Detected in many" "Adipocytes: 13.4;Cardiomyocytes: 20.1;Early spermatids: 27.7;Epicardial cells: 38.7;Late spermatids: 17.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" HPA041368 Uncertain Approved Vesicles NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" Vesicles "HPA041368: " "unprognostic (1.25e-1)" "unprognostic (8.79e-2)" "unprognostic (1.43e-1)" "unprognostic (7.58e-3)" ENSG00000284526 ENSG00000284526 "Novel protein" 17 76563710-76570544 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "skeletal muscle: 23.4" "Cell type enhanced" "Detected in many" "Epicardial cells: 66.0;Retinal pigment epithelial cells: 46.9;Salivary myoepithelial cells: 20.7;Thymic myoid cells: 31.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Skin - Outer root sheath cells, Testis - Late spermatids" "Not detected" "Not detected" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 40: Non-specific - Mixed function" "Cluster 8: Immune cells - Immune response" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" "unprognostic (2.80e-2)" "unprognostic (1.35e-1)" "unprognostic (2.54e-1)" "potential prognostic favorable (2.57e-4)" "unprognostic (8.59e-2)" "unprognostic (1.16e-1)" "unprognostic (2.41e-2)" "unprognostic (1.56e-2)" "potential prognostic unfavorable (4.60e-8)" "unprognostic (3.10e-2)" "unprognostic (3.26e-3)" "potential prognostic unfavorable (3.25e-4)" "unprognostic (2.22e-2)" "unprognostic (3.69e-2)" "unprognostic (3.48e-2)" "unprognostic (5.74e-2)" "unprognostic (3.82e-2)" "unprognostic (2.36e-1)" "unprognostic (2.06e-1)" "unprognostic (1.18e-1)" "unprognostic (1.39e-1)" "unprognostic (1.41e-1)" "unprognostic (1.02e-1)" "unprognostic (3.09e-1)" "unprognostic (7.86e-2)" "unprognostic (7.96e-2)" ENSG00000284554 ENSG00000284554 "Novel protein" 22 39014363-39033276 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 6 "lymphoid tissue: 2.7" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" HPA055116 Uncertain NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 5: Spleen - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 67: Plasma cells - Plasma cell differentiation" "HPA055116: " "unprognostic (2.21e-2)" "potential prognostic favorable (1.52e-4)" "unprognostic (1.35e-2)" ENSG00000284684 ENSG00000284684 "Novel protein" 4 6064977-6070162 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 33: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" ENSG00000284691 ENSG00000284691 "Novel zinc finger protein" 7 150400702-150412470 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "B-cells: 18.9;Parietal cells: 24.8;pDCs: 18.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 3.9;MAIT T-cell: 3.0;memory B-cell: 5.2;memory CD4 T-cell: 5.4;memory CD8 T-cell: 3.5;naive B-cell: 6.1;naive CD4 T-cell: 6.0;naive CD8 T-cell: 4.1;plasmacytoid DC: 8.0;T-reg: 3.9" "Group enriched" "Detected in many" 6 "B-cells: 6.1;dendritic cells: 8.0;T-cells: 6.0" "Cancer enhanced" "Detected in many" "Myeloma: 16.4" "Low region specificity" "Detected in all" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 15: Non-specific - Protein processing" "unprognostic (9.92e-2)" "unprognostic (3.39e-2)" "unprognostic (6.58e-3)" "unprognostic (8.54e-2)" "unprognostic (1.64e-1)" "unprognostic (5.01e-2)" "unprognostic (1.02e-1)" "unprognostic (7.14e-3)" "unprognostic (2.30e-1)" "unprognostic (3.28e-2)" "unprognostic (2.36e-1)" "unprognostic (2.00e-2)" "unprognostic (3.30e-2)" "unprognostic (1.47e-1)" "unprognostic (4.29e-2)" "potential prognostic favorable (5.15e-5)" "unprognostic (8.20e-2)" "unprognostic (8.40e-2)" "unprognostic (1.98e-2)" "unprognostic (3.87e-1)" "unprognostic (1.35e-2)" "unprognostic (1.82e-1)" "unprognostic (1.53e-2)" "unprognostic (1.38e-1)" ENSG00000284732 ENSG00000284732 "Novel olfactory receptor" 11 56459221-56473352 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 9: Non-specific - Receptor signaling" "Cluster 56: Non-specific - Sensory perception" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" ENSG00000284762 ENSG00000284762 "Phosphodiesterase 8B" 5 77086732-77427124 "Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 11.7" "Cell type enhanced" "Detected in many" "Adipocytes: 54.8;Adrenal medulla cells: 21.3;Fallopian tube ciliated cells: 19.2;Prostatic glandular cells: 54.8;Renal collecting duct intercalated cells: 16.1;Renal collecting duct principal cells: 14.5;Renal connecting tubule cells: 29.0" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 2.1;Thyroid Carcinoma (TCGA): 2.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" HPA036912 Supported NA NA "Cluster 61: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 89: Adipocytes - Lipid metabolism" "HPA036912: " "unprognostic (5.70e-3)" "unprognostic (2.43e-1)" "unprognostic (9.43e-2)" "unprognostic (7.34e-2)" ENSG00000284773 ENSG00000284773 "Novel protein" 1 34974356-34985313 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Renal collecting duct principal cells: 6.9;Renal connecting tubule cells: 7.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" NA NA "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 6: Leukemia - Signal transduction" "Cluster 102: Non-specific - Mixed function" "unprognostic (2.32e-1)" "unprognostic (7.64e-3)" "unprognostic (1.63e-1)" "unprognostic (2.31e-1)" "unprognostic (2.47e-2)" "unprognostic (4.26e-2)" "unprognostic (8.92e-2)" ENSG00000284776 ENSG00000284776 "Novel protein" 20 18567453-18744216 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 10.6;Myonuclei: 3.6;Retinal ganglion cells: 3.9;Tuft cells: 11.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA040981 Uncertain Uncertain Nucleoli,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 95: Tuft cells - Chemosensory signaling" "Nucleoli, Cytosol" "HPA040981: " "unprognostic (1.29e-1)" "unprognostic (2.46e-2)" "unprognostic (1.10e-2)" "unprognostic (1.03e-1)" "unprognostic (4.03e-2)" "unprognostic (1.58e-2)" "unprognostic (2.98e-1)" "unprognostic (8.54e-2)" "unprognostic (2.15e-3)" "unprognostic (1.70e-2)" "unprognostic (1.74e-1)" "potential prognostic unfavorable (1.47e-4)" "unprognostic (7.34e-2)" "unprognostic (2.19e-2)" "unprognostic (3.63e-2)" "unprognostic (1.14e-1)" "unprognostic (8.20e-2)" "unprognostic (1.22e-1)" "unprognostic (3.25e-1)" "unprognostic (1.34e-2)" "unprognostic (2.79e-3)" "unprognostic (8.00e-2)" "unprognostic (3.50e-1)" "unprognostic (3.25e-1)" "unprognostic (9.92e-2)" "unprognostic (4.33e-1)" ENSG00000284779 ENSG00000284779 "Novel protein" 11 2131395-2149603 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 39 "liver: 12.2" "Not detected" "Not detected" "Group enriched" "Detected in some" 55 "fibroblast: 2.9;pericyte: 10.2;vascular associated smooth muscle cell: 3.4" "Group enriched" "Detected in some" 9 "Liver Hepatocellular Carcinoma (TCGA): 2.3;Ovary Serous Cystadenocarcinoma (TCGA): 7.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 9 "Sarcoma: 1.9" "Liver - Hepatocytes, Pancreas - Beta cells" "Not detected" "Not detected" HPA071234 Approved Nucleoplasm "Intracellular and membrane" NA NA "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 22: Non-specific - Basic cellular functions" Nucleoplasm "HPA071234: " "unprognostic (4.19e-3)" "unprognostic (1.58e-2)" ENSG00000284797 ENSG00000284797 "Novel protein" 19 18249950-18255419 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "intestine: 3.0;stomach 1: 1.4;testis: 1.3" "Cell type enhanced" "Detected in some" "Colonocytes: 204.2;Enteric stem cells: 41.0;Enteric transient amplifying cells: 87.1;Enterocytes: 58.3;Esophageal apical cells: 109.9;Foveolar cells: 140.1;Gastric progenitor cells: 123.0;Goblet cells: 36.0;Late spermatids: 34.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Colon Adenocarcinoma (TCGA): 3.4;Pancreatic Adenocarcinoma (TCGA): 3.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "Esophageal cancer: 7.1" "Colon - Colon enterocytes, Prostate - Urothelial cells, Stomach - Gastric mucous cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 17: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" "unprognostic (6.37e-2)" "unprognostic (1.30e-2)" "unprognostic (1.05e-1)" "unprognostic (1.51e-1)" ENSG00000284895 ENSG00000284895 "Novel protein" 1 41585306-41628816 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" ENSG00000284906 ENSG00000284906 "Novel protein" 15 30624548-30773002 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.2;lymphoid tissue: 4.8;retina: 4.7" "Cell type enhanced" "Detected in some" "B-cells: 1.4;Distal convoluted tubule cells: 2.7;Late spermatids: 1.7;Loop of henle epithelial cells: 3.2;Papillary tip epithelial cells: 9.3;Podocytes: 3.9;Proximal tubule cells: 3.7;Renal collecting duct intercalated cells: 2.8;Renal collecting duct principal cells: 9.6;Renal connecting tubule cells: 4.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" HPA064479 Uncertain NA Yes "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 6: Non-specific - Immune response" "Cluster 56: Non-specific - Sensory perception" "Cluster 105: Non-specific - Mixed function" "HPA064479: " ENSG00000284931 ENSG00000284931 "Novel protein" 11 5248270-5254783 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 23 "placenta: 4081.1" "Group enriched" "Detected in some" 16 "Erythrocyte progenitors: 167.6;Erythrocytes: 97.0;Platelets: 46.3" "Cell type enriched" "Detected in single" 4 "deep-layer near-projecting: 3.0" "Group enriched" "Detected in some" 9 "Glioblastoma Multiforme (TCGA): 3.3;Kidney Renal Clear Cell Carcinoma (TCGA): 4.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 57 "Leukemia: 1897.6" HPA043234 Uncertain NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 47: Endothelial cells - Vasculature" "Cluster 47: Leukemia - Hemostasis" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" "HPA043234: " "unprognostic (5.42e-2)" "unprognostic (3.14e-3)" ENSG00000284934 ENSG00000284934 "Novel protein" 12 122207662-122227534 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 5 "adrenal gland: 2.8" "Cell type enriched" "Detected in single" 11 "Paneth cells: 3.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 18 "Neuroblastoma: 9.7" NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 29: Forebrain - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 15: Non-specific - Protein processing" ENSG00000284956 ENSG00000284956 "Novel protein" 8 23084403-23115536 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "bone marrow: 1.2;gallbladder: 1.4;testis: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 8.5" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in some" 7 "neutrophil: 223.8" "Lineage enriched" "Detected in many" 142 "granulocytes: 223.8" "Low cancer specificity" "Detected in all" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 15: Kidney cancer - Membrane components" "Cluster 24: Neutrophils - Innate immunity signal integration" "unprognostic (6.51e-2)" "unprognostic (1.85e-1)" "unprognostic (9.04e-2)" "unprognostic (1.35e-1)" "unprognostic (2.64e-1)" "unprognostic (2.31e-1)" "unprognostic (1.70e-1)" "unprognostic (8.20e-3)" "unprognostic (1.59e-2)" "unprognostic (9.21e-3)" "unprognostic (2.87e-1)" "unprognostic (3.08e-1)" "unprognostic (1.33e-2)" "unprognostic (8.14e-3)" "potential prognostic favorable (8.67e-6)" "unprognostic (6.97e-2)" "unprognostic (3.97e-1)" "unprognostic (1.84e-1)" "unprognostic (5.58e-3)" ENSG00000284969 ENSG00000284969 "Novel protein" 11 33698261-33722467 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Breast secretory cells: 5.8;Conjunctival goblet cells: 3.9;Endometrial secretory cells: 7.1;Esophageal apical cells: 9.7;Melanocytes: 4.0;Vascular endothelial cells: 3.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" HPA026494 Uncertain Uncertain "Golgi apparatus,Vesicles" NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 44: Non-specific - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "Golgi apparatus, Vesicles" "HPA026494: " "unprognostic (6.44e-2)" "unprognostic (3.28e-1)" "unprognostic (1.50e-2)" "unprognostic (2.09e-3)" "unprognostic (3.16e-1)" "unprognostic (1.44e-1)" "unprognostic (2.03e-2)" "unprognostic (5.12e-3)" "unprognostic (1.50e-1)" "unprognostic (7.14e-2)" "unprognostic (7.43e-2)" "unprognostic (7.35e-3)" "unprognostic (1.68e-3)" "potential prognostic unfavorable (2.99e-5)" "unprognostic (1.22e-1)" "unprognostic (1.16e-2)" "unprognostic (2.60e-1)" ENSG00000284976 ENSG00000284976 "Novel RING finger protein" 9 137217494-137219361 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "esophagus: 65.5" "Cell type enhanced" "Detected in some" "Astrocytes: 11.1;Bergmann glia: 5.3;Brain inhibitory neurons: 4.0;Choroid plexus epithelial cells: 4.4;Distal convoluted tubule cells: 6.6;Ependymal cells: 5.5;Loop of henle epithelial cells: 6.7;Microglia: 5.7;Oligodendrocyte progenitor cells: 4.3;Oligodendrocytes: 9.5;Papillary tip epithelial cells: 8.2;Podocytes: 10.3;Proximal tubule cells: 11.5;Renal collecting duct intercalated cells: 7.6;Renal collecting duct principal cells: 5.0;Renal connecting tubule cells: 9.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "prostate cancer: 17.6" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 6: Non-specific - Immune response" "Cluster 35: RS4;11 - Unknown function" "Cluster 102: Non-specific - Mixed function" "unprognostic (2.64e-1)" "unprognostic (2.02e-1)" "unprognostic (1.56e-1)" "unprognostic (7.79e-3)" "unprognostic (2.99e-2)" "unprognostic (1.31e-1)" "unprognostic (6.94e-3)" "unprognostic (6.29e-3)" "potential prognostic unfavorable (1.86e-5)" "unprognostic (1.13e-2)" "unprognostic (1.08e-2)" "potential prognostic unfavorable (3.82e-4)" "unprognostic (2.66e-1)" "unprognostic (1.92e-1)" "unprognostic (1.88e-2)" "unprognostic (4.77e-3)" "unprognostic (4.69e-2)" "unprognostic (1.78e-1)" "unprognostic (4.40e-1)" "unprognostic (7.46e-2)" "unprognostic (7.72e-2)" "unprognostic (1.61e-1)" "unprognostic (3.19e-2)" "unprognostic (5.98e-2)" "unprognostic (4.55e-2)" "unprognostic (1.74e-2)" ENSG00000285025 ENSG00000285025 "Mitochondrial elongation factor 1" L0R8F8 22 39504231-39504443 "Predicted intracellular proteins" "Ribosome biogenesis, Translation regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 11 "skeletal muscle: 4.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Skin Cutaneous Melanoma (TCGA): 2.7" "Region enhanced" "Detected in some" "choroid plexus: 2.8" "Immune cell enhanced" "Detected in single" "eosinophil: 1.0" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 17: Choroid plexus - Cilium" "Cluster 61: BICR 18 - Protein kinases" 4 "unprognostic (6.87e-2)" ENSG00000285043 ENSG00000285043 "Novel protein" 16 30053123-30070414 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in all" 7 "tongue: 96.7" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 6.3;Cone photoreceptor cells: 8.3;Ependymal cells: 14.6;Fallopian tube ciliated cells: 6.1;Respiratory ciliated cells: 12.7;Respiratory deuterosomal cells: 8.3;Rod photoreceptor cells: 12.0" "Cell type enhanced" "Detected in many" "ependymal cell: 17.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Testis - Early spermatids" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 29: Forebrain - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 79: Photoreceptor cells - Phototransduction" "unprognostic (2.82e-2)" "unprognostic (2.66e-2)" "potential prognostic favorable (9.93e-4)" "unprognostic (2.05e-2)" "unprognostic (3.02e-1)" "unprognostic (8.31e-2)" "unprognostic (3.46e-2)" "unprognostic (2.77e-3)" "potential prognostic favorable (5.53e-4)" "unprognostic (9.06e-3)" "unprognostic (1.85e-1)" "unprognostic (6.61e-3)" "unprognostic (1.30e-3)" "unprognostic (1.70e-1)" "unprognostic (7.63e-2)" "unprognostic (1.01e-1)" "unprognostic (2.50e-1)" "unprognostic (5.35e-3)" "unprognostic (1.14e-1)" "unprognostic (1.39e-1)" "unprognostic (6.57e-3)" "unprognostic (3.86e-1)" "unprognostic (5.13e-1)" "unprognostic (7.72e-2)" "unprognostic (1.04e-1)" ENSG00000285082 ENSG00000285082 "Novel protein" 9 117704157-118083691 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "retina: 2.2" "Cell type enhanced" "Detected in many" "Astrocytes: 414.5;Bergmann glia: 207.8;Ependymal cells: 44.6;Macrophages: 35.3;Microglia: 84.8;Neutrophils: 115.1" "Cell type enhanced" "Detected in many" "astrocyte: 447.7;Bergmann glia: 211.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in single" 5 "Gallbladder cancer: 4.0" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 28: Astrocytes - Homeostasis & neuron support" "unprognostic (1.28e-1)" "unprognostic (1.06e-1)" "unprognostic (3.14e-2)" "unprognostic (3.00e-1)" "potential prognostic unfavorable (1.53e-5)" ENSG00000285085 ENSG00000285085 "Novel protein" 6 32150495-32154373 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 1.3;Loop of henle epithelial cells: 1.3;Podocytes: 1.0;Renal collecting duct principal cells: 2.4;Renal connecting tubule cells: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 4: Non-specific - Transcription" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" ENSG00000285130 ENSG00000285130 "Novel protein" 9 69035747-69255187 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "Megakaryocyte-Erythroid progenitors: 40.0;Myonuclei: 49.3;Respiratory ciliated cells: 59.5" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Ovary Serous Cystadenocarcinoma (TCGA): 1.1;Stomach Adenocarcinoma (TCGA): 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001813, HPA068304, HPA070714" Uncertain Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 55: Myocytes - Oxidative muscle function" "Nucleoplasm, Plasma membrane, Cell Junctions" "HPA001813: , HPA068304: , HPA070714: " "unprognostic (2.83e-1)" "unprognostic (5.89e-2)" ENSG00000285133 ENSG00000285133 "Novel protein" P0DPQ6 12 57517712-57520480 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skeletal muscle: 17.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney Renal Papillary Cell Carcinoma (TCGA): 5.2;Stomach Adenocarcinoma (TCGA): 11.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 13 "basophil: 9.6;neutrophil: 21.5" "Lineage enriched" "Detected in many" 19 "granulocytes: 21.5" "Cancer enhanced" "Detected in many" "Gastric cancer: 4.7" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 5: Non-specific - Mixed function" "Cluster 61: BICR 18 - Protein kinases" "unprognostic (1.37e-1)" "unprognostic (3.78e-1)" "unprognostic (1.54e-2)" ENSG00000285188 ENSG00000285188 "Novel protein" 19 18207961-18255419 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 6.4;Breast myoepithelial cells: 15.5;Colonocytes: 10.3;Enteric stem cells: 8.5;Enteric transient amplifying cells: 6.3;Epididymal basal cells: 8.0;Foveolar cells: 10.2;Paneth cells: 7.7;pDCs: 11.6" "Cancer enhanced" "Detected in some" "Thyroid Carcinoma (TCGA): 2.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Gallbladder cancer: 1.1" "HPA048975, HPA054218" Uncertain Approved "Midbody ring,Centrosome,Basal body,Cytosol" Yes NA "Cluster 74: Non-specific - Signal transduction" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 20: Non-specific - Transcription regulation" "Centrosome, Basal body, Cytosol" "Midbody ring" "HPA048975: , HPA054218: " "unprognostic (3.53e-1)" "unprognostic (5.82e-2)" "unprognostic (7.27e-2)" "unprognostic (1.41e-1)" ENSG00000285218 ENSG00000285218 "Novel protein" 3 170418868-170860380 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 6.1" "Group enriched" "Detected in some" 10 "Oligodendrocytes: 239.1;Podocytes: 332.4" "Group enriched" "Detected in many" 9 "committed oligodendrocyte precursor: 112.4;fibroblast: 286.4;oligodendrocyte: 333.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" NA NA "Cluster 40: Non-specific - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 80: Oligodendrocytes - Myelination" "unprognostic (2.93e-2)" "unprognostic (1.97e-1)" "unprognostic (6.92e-2)" "unprognostic (3.12e-1)" "unprognostic (1.39e-1)" "unprognostic (2.00e-1)" "unprognostic (2.47e-2)" "unprognostic (9.00e-3)" "unprognostic (1.19e-1)" "unprognostic (3.56e-2)" "unprognostic (3.53e-3)" "unprognostic (3.73e-3)" "unprognostic (1.15e-1)" "unprognostic (1.14e-1)" "unprognostic (7.70e-2)" "potential prognostic unfavorable (6.18e-5)" "unprognostic (3.35e-1)" "unprognostic (7.58e-3)" "unprognostic (4.74e-2)" ENSG00000285245 ENSG00000285245 "Novel protein" 9 133098121-133163914 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 10.6;Breast lactating cells: 4.7;Erythrocyte progenitors: 12.3;Fibro-adipogenic progenitors: 5.5;Macrophages: 6.1;Megakaryocyte-Erythroid progenitors: 15.0;Neutrophils: 6.6;Retinal amacrine cells: 4.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Leukemia: 1.3" HPA025961 Uncertain Uncertain Nucleoplasm NA NA "Cluster 44: Non-specific - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" Nucleoplasm "HPA025961: " "unprognostic (3.89e-2)" "unprognostic (1.13e-1)" ENSG00000285253 ENSG00000285253 "Novel protein" 15 56652488-56918571 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 41.4;Fibro-adipogenic progenitors: 39.1;Loop of henle epithelial cells: 41.3;Podocytes: 81.8;Proximal tubule cells: 42.1;Renal connecting tubule cells: 39.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 55: Breast - Lactation" "Cluster 11: White matter - Signal transduction" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 105: Non-specific - Mixed function" 3 "unprognostic (1.47e-1)" "unprognostic (3.20e-1)" "unprognostic (3.66e-1)" "unprognostic (1.66e-1)" "unprognostic (4.10e-2)" "potential prognostic unfavorable (2.11e-4)" "unprognostic (6.89e-2)" "unprognostic (2.84e-3)" "validated prognostic favorable (8.01e-6)" "validated prognostic favorable (3.62e-5)" "unprognostic (3.43e-1)" "unprognostic (1.11e-2)" "unprognostic (1.01e-1)" "unprognostic (2.86e-1)" "unprognostic (8.58e-2)" "unprognostic (6.59e-3)" "unprognostic (1.38e-1)" "unprognostic (2.35e-1)" "unprognostic (8.68e-2)" "unprognostic (3.39e-2)" "unprognostic (2.07e-2)" "unprognostic (2.01e-1)" "unprognostic (1.72e-2)" "unprognostic (1.93e-1)" "unprognostic (6.82e-2)" ENSG00000285283 ENSG00000285283 "Novel protein" 11 31812391-32104665 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 8.2;lymphoid tissue: 5.2;retina: 6.6" "Group enriched" "Detected in some" 4 "Early spermatids: 86.9;Late primary spermatocytes: 92.2;Late spermatids: 49.3;Retinal amacrine cells: 67.2;Retinal ganglion cells: 30.9" "Group enriched" "Detected in some" 12 "astrocyte: 7.4;Bergmann glia: 17.4;upper rhombic lip: 16.7" "Group enriched" "Detected in many" 4 "Ovary Serous Cystadenocarcinoma (TCGA): 6.5;Stomach Adenocarcinoma (TCGA): 12.3" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" HPA038474 Uncertain Supported "Endoplasmic reticulum" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 25: Non-specific - Transcription" "Cluster 1: Neuronal - Visual perception" "Cluster 109: Neurons - Neuronal signaling" "Endoplasmic reticulum" "HPA038474: " "unprognostic (1.16e-1)" "potential prognostic unfavorable (6.08e-4)" "unprognostic (1.98e-2)" "unprognostic (1.75e-1)" "unprognostic (6.67e-2)" "unprognostic (2.01e-2)" "unprognostic (1.83e-1)" "unprognostic (3.29e-1)" "unprognostic (6.70e-1)" "unprognostic (2.13e-2)" "unprognostic (8.67e-2)" "unprognostic (8.36e-2)" ENSG00000285304 ENSG00000285304 "Novel protein" 22 37639693-37666932 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 8.3;intestine: 7.6" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 4.3;Myosatellite cells: 1.2;Prostatic hillock cells: 1.3;Thymocytes: 1.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" HPA000757 Approved Approved Cytosol NA NA "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 53: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" Cytosol "HPA000757: " "unprognostic (1.90e-2)" "unprognostic (1.70e-3)" "unprognostic (2.51e-1)" "unprognostic (6.54e-2)" "unprognostic (4.30e-2)" "unprognostic (1.03e-1)" "unprognostic (2.48e-1)" "potential prognostic favorable (9.12e-5)" "unprognostic (6.30e-3)" "unprognostic (1.95e-1)" "unprognostic (2.17e-2)" "unprognostic (7.24e-2)" "unprognostic (1.10e-2)" "unprognostic (1.53e-1)" "unprognostic (4.46e-3)" "unprognostic (2.43e-2)" "unprognostic (1.15e-2)" "unprognostic (1.80e-1)" "unprognostic (1.13e-1)" "unprognostic (3.00e-1)" "unprognostic (5.52e-2)" ENSG00000285330 ENSG00000285330 "Novel protein" 4 109713916-109801999 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "liver: 7.4" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 8.1;Epididymal efferent duct absorptive cells: 4.8;Loop of henle epithelial cells: 7.4;Papillary tip epithelial cells: 4.9;Proximal tubule cells: 21.2;Renal collecting duct intercalated cells: 3.4;Renal collecting duct principal cells: 6.5;Renal connecting tubule cells: 8.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "HPA001143, HPA024061, HPA035909" Uncertain NA NA "Cluster 76: Non-specific - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 88: Proximal tubular cells - Transmembrane transport" "HPA001143: , HPA024061: , HPA035909: " "unprognostic (5.85e-2)" "unprognostic (9.77e-2)" "unprognostic (6.84e-2)" "unprognostic (9.22e-2)" "unprognostic (4.74e-2)" "unprognostic (6.49e-2)" "unprognostic (1.22e-1)" "unprognostic (5.12e-2)" "potential prognostic favorable (4.06e-7)" "unprognostic (1.16e-2)" "unprognostic (3.68e-2)" "unprognostic (6.18e-2)" "unprognostic (2.82e-1)" "unprognostic (7.21e-3)" "unprognostic (4.67e-2)" "unprognostic (2.44e-1)" "unprognostic (1.56e-1)" "unprognostic (9.66e-3)" "unprognostic (5.87e-2)" "unprognostic (2.91e-1)" "unprognostic (2.33e-2)" "unprognostic (5.65e-2)" "unprognostic (4.71e-2)" "unprognostic (1.55e-1)" "unprognostic (3.66e-1)" "unprognostic (4.07e-1)" ENSG00000285382 ENSG00000285382 "Novel protein" 20 32632183-32743567 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.3;retina: 1.2" "Cell type enhanced" "Detected in many" "Retinal amacrine cells: 44.6;Retinal bipolar cells: 32.9;Retinal ganglion cells: 34.8;Retinal horizontal cells: 40.1" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA054119 Approved Vesicles NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 9: Non-specific - Receptor signaling" "Cluster 47: Leukemia - Hemostasis" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 7 Vesicles "HPA054119: " ENSG00000285404 ENSG00000285404 "Novel protein, DEPDC5-YWHAH readthrough" 22 31754899-31956243 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "Platelets: 19.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA054969, HPA055619" Uncertain NA NA "Cluster 61: BICR 18 - Protein kinases" "Cluster 87: B-cells - Adaptive immunity: Humoral response" "HPA054969: , HPA055619: " ENSG00000285446 ENSG00000285446 "Novel protein" 6 116399395-116463696 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "cDC: 5.7;Endometrial secretory cells: 4.9;Epicardial cells: 20.5;Epididymal basal cells: 5.4;Fibro-adipogenic progenitors: 4.7;Hepatic stellate cells: 6.5;Macrophages: 7.1;Mesothelial cells: 8.7;monocytes: 12.5;Neutrophils: 16.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Gallbladder cancer: 1.3" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" "unprognostic (2.65e-3)" "unprognostic (1.01e-1)" ENSG00000285458 ENSG00000285458 "Novel protein" 4 86886472-86936178 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Myonuclei: 42.8;Renal collecting duct principal cells: 33.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" HPA057434 Uncertain Approved "Focal adhesion sites,Cytosol" NA NA "Cluster 61: Non-specific - Transcription" "Cluster 9: Non-specific - Receptor signaling" "Cluster 56: Non-specific - Sensory perception" "Cluster 70: Intestinal goblet cells - Mucin production" "Focal adhesion sites" Cytosol "HPA057434: " "unprognostic (7.26e-3)" "unprognostic (5.46e-2)" "unprognostic (1.76e-2)" "unprognostic (4.50e-3)" "unprognostic (3.75e-3)" "unprognostic (9.74e-2)" "unprognostic (2.79e-1)" "potential prognostic unfavorable (1.95e-4)" "unprognostic (2.30e-1)" "potential prognostic favorable (6.47e-4)" "unprognostic (4.68e-2)" "unprognostic (2.47e-2)" "unprognostic (1.94e-2)" "unprognostic (1.70e-1)" "unprognostic (4.75e-2)" "unprognostic (1.59e-1)" "unprognostic (8.45e-3)" "unprognostic (1.48e-1)" "unprognostic (8.47e-3)" "unprognostic (8.23e-3)" "unprognostic (7.98e-2)" "unprognostic (1.20e-1)" "unprognostic (4.66e-3)" "unprognostic (1.07e-1)" ENSG00000285471 ENSG00000285471 "Novel protein" 17 5772926-6080792 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 5.8;Differentiating spermatogonia: 9.4;Oocytes: 13.8;Respiratory ionocytes: 5.1;Retinal ganglion cells: 3.9;Undifferentiated spermatogonia: 24.2" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Sarcoma: 14.7" NA NA "Cluster 49: Hindbrain - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 106: Spermatogonia - Spermatogonial differentiation" ENSG00000285526 ENSG00000285526 "Novel protein" 19 35106510-35124297 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "choroid plexus: 4.6;salivary gland: 7.0" "Cell type enhanced" "Detected in some" "Colonocytes: 1.3;Gastric chief cells: 2.2;Müller glia: 2.4;Retinal pigment epithelial cells: 4.3;Schwann cells: 4.2" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 9.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 4.4" HPA010856 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 60: Stomach - Digestion" "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" Nucleoplasm "Plasma membrane" "HPA010856: " "potential prognostic unfavorable (6.14e-6)" "unprognostic (2.30e-1)" "unprognostic (6.65e-3)" "unprognostic (5.30e-3)" "unprognostic (1.77e-1)" "potential prognostic favorable (6.65e-4)" "unprognostic (1.56e-1)" "unprognostic (2.33e-1)" "unprognostic (1.96e-2)" "unprognostic (1.42e-1)" "unprognostic (4.63e-3)" "unprognostic (2.13e-2)" "unprognostic (2.67e-1)" ENSG00000285547 ENSG00000285547 "Novel protein" X 72301691-72572843 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 6 "epididymis: 1.2" "Cell type enhanced" "Detected in some" "Adipocytes: 4.3;Cone photoreceptor cells: 4.1;Epididymal principal cells: 6.3;Lactotrophs: 3.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA048560, HPA049051" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" Nucleoplasm Cytosol "HPA048560: , HPA049051: " ENSG00000285566 ENSG00000285566 "Novel keratin-associated protein" 13 63832361-63833053 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "breast: 3.0;testis: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 15 "skin cancer: 1.5;testis cancer: 1.5" "Testis - Early spermatids" NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" ENSG00000285585 ENSG00000285585 "Novel protein" 3 119703076-119807570 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 16.7;Endometrial ciliated cells: 9.3;Ependymal cells: 20.1;Epididymal efferent duct ciliated cells: 18.0;Fallopian tube ciliated cells: 11.4;Granulosa cells: 6.5;Late primary spermatocytes: 10.6;Respiratory ciliated cells: 19.9;Rod photoreceptor cells: 7.3" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 17.9;ependymal cell: 17.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA074084 Uncertain NA NA "Cluster 20: Myeloma - Immune response" "Cluster 34: Ciliated cells - Cilia assembly & function" "HPA074084: " ENSG00000285625 ENSG00000285625 "Novel protein" 12 56714612-56741535 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "skeletal muscle: 3.3" "Cell type enhanced" "Detected in some" "Gastric chief cells: 2.2;Paneth cells: 3.9" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 26.7" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" HPA073152 Approved Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 110: Mural cells - ECM organization" Cytosol "HPA073152: " "unprognostic (8.20e-2)" "unprognostic (4.97e-2)" "unprognostic (4.78e-3)" "unprognostic (9.54e-2)" "unprognostic (1.08e-1)" "unprognostic (4.11e-2)" "unprognostic (1.87e-1)" "unprognostic (3.05e-1)" "unprognostic (2.38e-1)" "unprognostic (2.50e-1)" "unprognostic (1.72e-1)" "unprognostic (7.50e-3)" "unprognostic (1.08e-2)" "unprognostic (5.40e-2)" "unprognostic (4.68e-2)" "unprognostic (2.64e-1)" "unprognostic (1.56e-1)" "unprognostic (1.28e-1)" "potential prognostic favorable (5.30e-6)" "potential prognostic unfavorable (7.05e-4)" "unprognostic (9.95e-2)" "unprognostic (1.60e-1)" "unprognostic (4.19e-2)" "unprognostic (3.83e-2)" ENSG00000285655 ENSG00000285655 "Novel protein" 8 66430185-66445324 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Adipocytes: 8.2;Cardiomyocytes: 17.1;Myonuclei: 5.0;Smooth muscle cells: 3.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 11 "Rhabdoid: 2.3" NA NA "Cluster 5: Rhabdoid - Unknown function" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" ENSG00000285708 ENSG00000285708 "Novel protein" 3 70959226-71754229 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in many" 5 "Neutrophils: 455.5" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA003876 Uncertain Approved Nucleoplasm NA NA "Cluster 31: Non-specific - Transcription" "Cluster 24: Neutrophils - Innate immunity signal integration" Nucleoplasm "HPA003876: " ENSG00000285733 ENSG00000285733 "Novel protein" 6 169419969-169702047 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 6 "Epicardial cells: 61.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 37: Neurons - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" "unprognostic (1.98e-1)" "unprognostic (7.51e-3)" "unprognostic (3.88e-2)" "unprognostic (4.53e-2)" ENSG00000285749 ENSG00000285749 "Novel protein" 3 51798803-51830856 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "testis: 2.9" "Cell type enriched" "Detected in some" 5 "Late spermatids: 670.4" "Cell type enhanced" "Detected in some" "deep-layer corticothalamic and 6b: 4.1;deep-layer near-projecting: 1.1" "Cancer enhanced" "Detected in single" "Stomach Adenocarcinoma (TCGA): 1.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Testis - Early spermatids, Testis - Late spermatids" HPA055755 Approved Nucleoli NA NA "Cluster 47: Testis - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 56: Non-specific - Sensory perception" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" Nucleoli "HPA055755: " "unprognostic (3.59e-2)" "unprognostic (3.81e-2)" "unprognostic (1.36e-1)" ENSG00000285772 ENSG00000285772 "Novel protein" 7 92112159-92179511 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "breast: 2.5;testis: 7.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 57: Testis - Spermatogenesis" "Cluster 30: White matter - Myelination" "Cluster 5: Rhabdoid - Unknown function" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" "unprognostic (1.04e-3)" "unprognostic (9.34e-3)" "unprognostic (1.62e-2)" "unprognostic (2.58e-3)" "unprognostic (2.20e-1)" "unprognostic (2.15e-1)" "unprognostic (1.07e-1)" "unprognostic (7.52e-2)" "unprognostic (5.98e-2)" "unprognostic (1.66e-2)" "unprognostic (3.79e-1)" "unprognostic (7.83e-2)" ENSG00000285827 ENSG00000285827 "Novel protein" 11 118401602-118482737 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.8" "Group enriched" "Detected in some" 6 "Cardiomyocytes: 17.6;Epicardial cells: 6.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" HPA044629 Uncertain Approved "Mitochondria,Principal piece" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 15: Bone marrow - Innate immune response" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" Mitochondria "Principal piece" "HPA044629: " "unprognostic (1.14e-1)" "unprognostic (5.54e-2)" "unprognostic (1.49e-1)" "unprognostic (1.56e-1)" "unprognostic (2.35e-2)" "unprognostic (2.81e-3)" "unprognostic (6.10e-3)" "unprognostic (1.03e-2)" "unprognostic (3.50e-3)" "unprognostic (1.25e-2)" "unprognostic (1.45e-1)" "unprognostic (8.62e-2)" "unprognostic (8.18e-2)" "unprognostic (5.51e-3)" "unprognostic (1.27e-2)" "unprognostic (7.99e-2)" "unprognostic (2.58e-2)" "potential prognostic favorable (6.69e-4)" "unprognostic (1.33e-2)" "unprognostic (2.94e-2)" "unprognostic (3.54e-1)" "unprognostic (7.02e-2)" ENSG00000285837 ENSG00000285837 "Novel protein" 10 62374192-62672011 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "gallbladder: 1.3" "Group enriched" "Detected in some" 4 "Oligodendrocyte progenitor cells: 159.6;Oligodendrocytes: 181.8" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 332.5;oligodendrocyte precursor cell: 185.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA052446 Uncertain Approved "Vesicles,Centriolar satellite,Centrosome" NA NA "Cluster 13: Lung - Secretion" "Cluster 53: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" "Vesicles, Centriolar satellite, Centrosome" "HPA052446: " "unprognostic (9.75e-2)" "unprognostic (1.89e-1)" ENSG00000285868 ENSG00000285868 "Novel protein" 5 157341596-157460100 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "intestine: 6.5" "Cell type enhanced" "Detected in many" "B-cells: 43.0;Cardiomyocytes: 103.1;Cone photoreceptor cells: 31.1;NK-cells: 29.1;Retinal amacrine cells: 37.7;Retinal bipolar cells: 40.1;Retinal ganglion cells: 42.5;Retinal horizontal cells: 58.1;Rod photoreceptor cells: 37.7;T-cells: 26.0;Thymocytes: 54.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 77: Intestine - Digestion" "Cluster 15: Non-specific - Transcription" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" "unprognostic (1.64e-2)" ENSG00000285880 ENSG00000285880 "ADRB3-GOT1L1 readthrough" 8 37934340-37965953 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Adipocytes: 1.6;cDC: 1.1;Endometrial glandular cells: 1.9;Endometrial luminal cells: 1.5;Foveolar cells: 2.1;Late primary spermatocytes: 1.3;Ovarian stromal cells: 3.1;Smooth muscle cells: 3.1;Syncytiotrophoblasts: 1.1" "Cell type enhanced" "Detected in some" "amygdala excitatory: 5.2;CGE interneuron: 4.4;LAMP5-LHX6 and Chandelier: 4.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA061969, HPA065408" Uncertain Uncertain "Vesicles,Basal body" NA NA "Cluster 48: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 94: Gonadal somatic cells - Mixed function" "Vesicles, Basal body" "HPA061969: , HPA065408: " "unprognostic (7.38e-2)" ENSG00000285920 ENSG00000285920 "Novel protein" 15 41284007-41380996 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 17 "Astrocytes: 5.4;Bergmann glia: 5.6;Brain excitatory neurons: 2.8;Brain inhibitory neurons: 2.9;Choroid plexus epithelial cells: 7.9;Ependymal cells: 4.4;Microglia: 3.3;Oligodendrocyte progenitor cells: 2.2;Oligodendrocytes: 3.3;Other brain neurons: 2.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "HPA042904, HPA074847" Uncertain Approved "Nucleoplasm,Nucleoli,Nucleoli fibrillar center" Yes Yes "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 61: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 22: Non-specific - Basic cellular functions" "Nucleoplasm, Nucleoli, Nucleoli fibrillar center" "HPA042904: , HPA074847: " "unprognostic (9.15e-2)" "unprognostic (2.32e-1)" "unprognostic (5.94e-2)" "unprognostic (2.55e-2)" "unprognostic (1.33e-1)" "unprognostic (1.59e-1)" "potential prognostic favorable (8.79e-4)" "unprognostic (1.64e-1)" "unprognostic (1.25e-2)" "unprognostic (2.15e-1)" "unprognostic (1.46e-1)" "unprognostic (3.04e-2)" ENSG00000285938 ENSG00000285938 "BCL6 antisense 1" 3 187743686-187746028 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 4 "bone marrow: 6.6;skeletal muscle: 21.4" "Group enriched" "Detected in many" 5 "Adipocytes: 247.7;Cardiomyocytes: 337.8;Epicardial cells: 297.9;Neutrophils: 94.8" "Cell type enhanced" "Detected in some" "astrocyte: 6.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 11 "neutrophil: 10.3" "Lineage enriched" "Detected in single" 12 "granulocytes: 10.3" "Cancer enhanced" "Detected in some" "lymphoma: 4.7" "Kidney - Macrophages, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 44: Non-specific - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "unprognostic (1.27e-1)" "unprognostic (1.21e-1)" "unprognostic (2.68e-1)" "unprognostic (1.49e-1)" "unprognostic (5.18e-3)" "unprognostic (7.19e-2)" "unprognostic (3.48e-2)" ENSG00000285947 ENSG00000285947 "Novel protein" 17 63917203-63931385 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 7 "pituitary gland: 2.3" "Group enriched" "Detected in some" 4 "B-cells: 3.5;pDCs: 3.9;Somatotrophs: 4.9" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "memory B-cell: 14.1;naive B-cell: 18.4" "Lineage enriched" "Detected in many" 5 "B-cells: 18.4" "Not detected" "Not detected" "HPA009178, HPA043715" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 20: Pituitary gland - Hormone signaling" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA009178: , HPA043715: " ENSG00000285953 ENSG00000285953 "Novel protein" 7 92144723-92245943 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 10 "testis: 6.1" "Cell type enhanced" "Detected in some" "Astrocytes: 9.6;Bergmann glia: 9.7;Brain excitatory neurons: 15.6;Brain inhibitory neurons: 18.7;Choroid plexus epithelial cells: 19.2;Early spermatids: 4.7;Ependymal cells: 11.7;Late spermatids: 22.6;Microglia: 5.6;Oligodendrocyte progenitor cells: 11.5;Oligodendrocytes: 14.7;Other brain neurons: 14.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049606, HPA079440" Uncertain Approved Vesicles NA NA "Cluster 67: Testis - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 22: Non-specific - Basic cellular functions" 2 Vesicles "HPA049606: , HPA079440: " "unprognostic (1.62e-1)" "unprognostic (1.42e-3)" "unprognostic (4.01e-1)" "unprognostic (1.91e-1)" "unprognostic (1.20e-1)" "unprognostic (2.03e-2)" ENSG00000285976 ENSG00000285976 "Novel protein" 6 63572472-63583587 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "liver: 35.7;skeletal muscle: 25.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "cervical cancer: 68.3" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 76: Non-specific - Metabolism" "Cluster 45: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 100: Stratified epithelial cells - Barrier functions" "unprognostic (9.23e-2)" "unprognostic (7.97e-2)" "unprognostic (7.75e-3)" "unprognostic (2.56e-2)" "unprognostic (3.25e-2)" "unprognostic (6.02e-2)" "unprognostic (7.32e-2)" "unprognostic (3.97e-2)" "potential prognostic favorable (1.01e-5)" "unprognostic (3.18e-3)" "unprognostic (6.36e-2)" "unprognostic (2.16e-2)" "unprognostic (1.18e-1)" "unprognostic (4.17e-1)" "unprognostic (1.63e-2)" "unprognostic (1.25e-1)" "unprognostic (2.24e-1)" "unprognostic (7.78e-3)" "unprognostic (9.68e-2)" "unprognostic (7.99e-2)" "unprognostic (9.46e-2)" "unprognostic (3.65e-2)" "unprognostic (3.56e-2)" "unprognostic (2.18e-1)" "unprognostic (1.14e-2)" "unprognostic (1.46e-1)" ENSG00000285982 ENSG00000285982 "Novel protein" 8 103398658-103501895 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "retina: 6.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 71.6;Early spermatids: 142.1;Epicardial cells: 211.5;Late primary spermatocytes: 86.5;Late spermatids: 684.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" HPA024763 Approved Nucleoplasm,Mitochondria NA NA "Cluster 42: Retina - Visual perception" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" Mitochondria Nucleoplasm "HPA024763: " "unprognostic (5.07e-2)" "unprognostic (6.94e-3)" "unprognostic (1.26e-1)" "unprognostic (2.20e-1)" "unprognostic (5.60e-2)" "unprognostic (5.44e-2)" "unprognostic (1.00e-1)" "unprognostic (1.80e-1)" "unprognostic (9.21e-2)" "unprognostic (9.91e-3)" "unprognostic (2.56e-2)" "unprognostic (7.08e-2)" "unprognostic (4.68e-2)" "unprognostic (3.15e-1)" "unprognostic (2.57e-1)" "unprognostic (4.20e-1)" ENSG00000286015 ENSG00000286015 "Novel protein" 1 248681249-248748349 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 11 "brain: 1.7" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 11.0;Brain inhibitory neurons: 6.2;Colonocytes: 51.7;Early spermatids: 11.1;Goblet cells: 43.5;Late spermatids: 12.9;Neuroendocrine cells: 13.4" "Cell type enhanced" "Detected in many" "deep-layer intratelencephalic: 28.6;upper-layer intratelencephalic: 39.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" ENSG00000286022 ENSG00000286022 "Novel protein" 20 2207328-2341059 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 1.6;esophagus: 2.9;fallopian tube: 3.2" "Cell type enhanced" "Detected in some" "Epididymal efferent duct ciliated cells: 10.1;Esophageal apical cells: 26.2;Fallopian tube ciliated cells: 7.9;Late primary spermatocytes: 10.9;Late spermatids: 8.7;Neutrophils: 8.9;Respiratory ciliated cells: 35.2" "Cancer enhanced" "Detected in some" "Prostate Adenocarcinoma (TCGA): 3.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 1.7" HPA004728 Uncertain NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" "HPA004728: " "unprognostic (5.75e-2)" "unprognostic (8.10e-2)" "unprognostic (2.74e-1)" ENSG00000286098 ENSG00000286098 "Novel protein" 19 11987641-12078106 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 10.6;Sertoli cells: 8.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" HPA046982 Uncertain NA NA "Cluster 24: Non-specific - Transcription" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 25: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 65: Non-specific - Cell growth & division" "HPA046982: " "unprognostic (5.72e-2)" "unprognostic (3.82e-1)" "unprognostic (8.73e-2)" "unprognostic (2.36e-1)" "unprognostic (1.17e-1)" "unprognostic (8.07e-3)" "unprognostic (4.34e-2)" "unprognostic (3.39e-2)" "unprognostic (2.56e-1)" "unprognostic (3.07e-2)" "unprognostic (1.95e-2)" "unprognostic (2.64e-2)" "unprognostic (2.24e-1)" "unprognostic (1.18e-1)" "unprognostic (1.98e-1)" "unprognostic (1.62e-1)" ENSG00000286112 ENSG00000286112 "Kynurenine aminotransferase 1" 9 128819663-128881931 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 14.5;Megakaryocytes: 6.2;Retinal ganglion cells: 7.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "HPA021176, HPA021177, HPA027736" Uncertain Approved Cytosol NA NA "Cluster 18: Non-specific - Translation" "Cluster 64: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 65: Non-specific - Cell growth & division" 1 Cytosol "HPA021176: , HPA021177: , HPA027736: " ENSG00000286131 ENSG00000286131 "Novel protein" 8 32647202-32647390 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 43: Hindbrain - Mixed function" ENSG00000286135 ENSG00000286135 "Novel protein similar to AQN-1 protein AQN-1 (Sus scrofa)" 10 122672850-122679494 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Tissue enriched" "Detected in single" 332 "epididymis: 111.6" "Cell type enriched" "Detected in some" 33 "Epididymal principal cells: 205.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Sebaceous gland cells" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 15: Kidney cancer - Membrane components" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" ENSG00000286143 ENSG00000286143 "Novel protein" 2 219491867-219498244 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "blood vessel: 5.0;skeletal muscle: 10.7" "Cell type enhanced" "Detected in some" "Epicardial cells: 6.8;Mesothelial cells: 1.1;Myonuclei: 8.6;Smooth muscle cells: 1.3;Thymic myoid cells: 1.4;Vascular smooth muscle cells: 2.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Neuroblastoma: 1.5" NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" ENSG00000286165 ENSG00000286165 "Novel protein" 2 189661519-189667881 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 6.9" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" HPA075042 Approved Cytosol NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 66: Non-specific - Mitochondria" Cytosol "HPA075042: " "unprognostic (1.22e-1)" "unprognostic (5.30e-1)" "unprognostic (1.14e-1)" "unprognostic (6.44e-2)" "unprognostic (6.45e-1)" "unprognostic (1.55e-1)" "unprognostic (6.54e-2)" ENSG00000286185 ENSG00000286185 "Novel protein, identical to neuroblastoma breakpoint family, member 19 NBPF19" 1 149390623-149556361 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "monocytes: 31.2;Myosatellite cells: 27.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050" Uncertain Approved "Golgi apparatus,Vesicles,Microtubules,Cytokinetic bridge,Primary cilium,Cytosol,Mid piece,Principal piece,End piece" Yes NA "Cluster 30: Non-specific - Gene expression regulation" "Cluster 15: Non-specific - Protein processing" "Primary cilium, Cytosol" "Golgi apparatus, Vesicles, Microtubules, Cytokinetic bridge, Mid piece, Principal piece, End piece" "HPA042595: , HPA043105: , HPA043692: , HPA044023: , HPA046971: , HPA058050: " ENSG00000286190 ENSG00000286190 "Novel protein" 17 5499427-5501006 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 8 "brain: 363.4;pituitary gland: 495.3" "Cell type enhanced" "Detected in some" "Astrocytes: 20.6;Bergmann glia: 24.9;Brain excitatory neurons: 51.7;Brain inhibitory neurons: 52.0;Ependymal cells: 51.9;Microglia: 19.1;Oligodendrocyte progenitor cells: 19.6;Other brain neurons: 166.9" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 8 "Glioblastoma Multiforme (TCGA): 280.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "basophil: 3.3" "Lineage enriched" "Detected in single" 11 "granulocytes: 3.3" "Cancer enhanced" "Detected in many" "Rhabdoid: 47.1" "Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Pancreas - Alpha cells, Prostate - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" "unprognostic (1.31e-1)" "unprognostic (2.46e-2)" "unprognostic (3.53e-2)" "unprognostic (2.77e-2)" "unprognostic (2.58e-2)" "unprognostic (7.15e-3)" "unprognostic (3.02e-3)" "unprognostic (6.54e-3)" "unprognostic (1.11e-2)" "unprognostic (1.81e-1)" "unprognostic (1.00e-1)" "unprognostic (8.48e-2)" "unprognostic (6.51e-2)" "unprognostic (1.62e-1)" "unprognostic (8.55e-2)" "unprognostic (5.02e-2)" "unprognostic (8.33e-3)" "potential prognostic favorable (3.44e-4)" "unprognostic (9.65e-2)" "unprognostic (4.27e-2)" "unprognostic (8.55e-2)" "unprognostic (1.01e-1)" "unprognostic (7.68e-2)" "unprognostic (2.51e-1)" "unprognostic (5.03e-2)" "unprognostic (5.96e-2)" ENSG00000286221 ENSG00000286221 "Novel protein" 16 80828736-81006894 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "Adipocytes: 12.6;Cardiomyocytes: 17.6;Myonuclei: 12.1;Prostatic glandular cells: 9.5;Retinal bipolar cells: 9.7;Thymocytes: 17.8;Tuft cells: 11.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 55: Lymphoma - Immune response" "Cluster 55: Myocytes - Oxidative muscle function" ENSG00000286224 ENSG00000286224 "Novel protein" 21 46326288-46326491 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 57: Stomach & Colon cancer - Digestion" "unprognostic (3.07e-1)" "unprognostic (8.62e-2)" ENSG00000286235 ENSG00000286235 "Novel protein" 20 5950949-6039856 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 4.3;Monocyte progenitors: 3.5;Myonuclei: 1.8;Neutrophil progenitors: 2.6;Retinal horizontal cells: 2.0;Thymic myoid cells: 2.7" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 6.2" "HPA045141, HPA066433" Approved Nucleoplasm,Cytosol NA NA "Cluster 61: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" Nucleoplasm Cytosol "HPA045141: , HPA066433: " "unprognostic (1.09e-2)" "unprognostic (3.08e-1)" "unprognostic (3.34e-1)" "unprognostic (6.71e-2)" "unprognostic (3.00e-2)" "unprognostic (1.72e-2)" "unprognostic (7.90e-3)" ENSG00000286264 ENSG00000286264 "Novel protein" 11 64241095-64244132 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cholangiocytes: 3.3;Endometrial ciliated cells: 3.8;Endometrial glandular cells: 3.6;Endometrial secretory cells: 5.8;Hepatocytes: 5.2;Parietal cells: 10.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.6" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 47: Endothelial cells - Vasculature" "Cluster 24: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" "unprognostic (2.09e-1)" "unprognostic (1.52e-1)" "unprognostic (2.02e-2)" "unprognostic (1.48e-2)" "unprognostic (1.59e-1)" "unprognostic (9.83e-2)" "unprognostic (2.03e-1)" "unprognostic (2.05e-1)" "unprognostic (2.77e-1)" "unprognostic (2.58e-1)" "potential prognostic favorable (2.57e-4)" "unprognostic (3.37e-2)" "unprognostic (3.31e-1)" "unprognostic (1.83e-1)" "unprognostic (2.72e-1)" "unprognostic (1.01e-1)" "unprognostic (8.02e-2)" "unprognostic (1.24e-1)" "unprognostic (1.34e-1)" "unprognostic (4.90e-1)" "unprognostic (4.63e-2)" "unprognostic (4.66e-1)" "unprognostic (1.76e-1)" "unprognostic (2.25e-1)" "unprognostic (2.01e-1)" "unprognostic (3.60e-1)" ENSG00000286268 ENSG00000286268 "Novel protein" X 48521806-48545469 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 8.9;Endometrial ciliated cells: 3.8;Endometrial glandular cells: 6.1;Endometrial luminal cells: 6.2;Endometrial secretory cells: 5.5;Rod photoreceptor cells: 13.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA003130 Uncertain Approved "Nuclear membrane,Endoplasmic reticulum" NA NA "Cluster 48: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 79: Photoreceptor cells - Phototransduction" "Nuclear membrane, Endoplasmic reticulum" "HPA003130: " ENSG00000287585 ENSG00000287585 "Novel protein, similar to CXorf51A" X 149414877-149415506 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Group enriched" "Detected in some" 55 "Early spermatids: 2.7;Late spermatids: 8.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" NA NA "Cluster 61: BICR 18 - Protein kinases" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" ENSG00000287856 ENSG00000287856 "Novel protein" 1 231363797-231528603 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 76.4;Early spermatids: 58.0;Late primary spermatocytes: 77.0;Late spermatids: 258.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 59.7;neutrophil: 44.1" "Lineage enriched" "Detected in all" 6 "granulocytes: 59.7" "Low cancer specificity" "Detected in all" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" "unprognostic (7.34e-2)" "unprognostic (6.94e-2)" "unprognostic (1.40e-2)" "unprognostic (4.92e-2)" "unprognostic (1.33e-1)" "unprognostic (3.30e-1)" "unprognostic (7.51e-2)" "potential prognostic unfavorable (9.85e-4)" "potential prognostic unfavorable (3.55e-4)" "unprognostic (6.78e-3)" "potential prognostic unfavorable (2.11e-4)" "potential prognostic unfavorable (1.07e-5)" "potential prognostic unfavorable (7.57e-5)" "unprognostic (6.27e-2)" "unprognostic (2.52e-1)" "unprognostic (1.78e-1)" "unprognostic (4.78e-2)" "unprognostic (2.28e-3)" "unprognostic (3.49e-1)" "unprognostic (1.79e-1)" "unprognostic (2.69e-2)" "unprognostic (5.70e-2)" "unprognostic (2.15e-1)" "unprognostic (6.68e-2)" "unprognostic (3.98e-3)" "unprognostic (4.01e-2)" ENSG00000288000 ENSG00000288000 "Novel protein" 20 43458054-43541881 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "pDCs: 84.9;Thymocytes: 77.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA059648 Approved "Nucleoplasm,Nuclear bodies,Midbody ring" Yes NA "Cluster 20: Non-specific - Transcription regulation" Nucleoplasm "Nuclear bodies, Midbody ring" "HPA059648: " ENSG00000288053 ENSG00000288053 "Novel protein" X 49071470-49079887 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Gastric chief cells: 1.1;Hematopoietic stem cells: 1.5" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in single" "neutrophil: 1.0" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.0" "Not detected" "Not detected" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 44: Non-specific - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 18: Adrenal cortex cells - Steroidogensis" ENSG00000288520 ENSG00000288520 "Novel protein" G9CGD6 6 154159828-154510114 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in single" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 28.8;Endometrial glandular cells: 34.5;Endometrial luminal cells: 61.4;Epididymal clear cells: 28.6;Lymphatic endothelial cells: 16.6;Myosatellite cells: 16.7;Retinal pigment epithelial cells: 21.3" "Cell type enhanced" "Detected in many" "midbrain-derived inhibitory: 6.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA028708, HPA028710, HPA049651" Uncertain Approved "Nucleoli,Nuclear speckles,Plasma membrane,Cytoplasmic bodies" NA NA "Cluster 55: Breast - Lactation" "Cluster 30: White matter - Myelination" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" "Nuclear speckles, Plasma membrane" "Nucleoli, Cytoplasmic bodies" "HPA028708: , HPA028710: , HPA049651: " "unprognostic (3.74e-2)" "potential prognostic favorable (2.24e-4)" "unprognostic (2.28e-1)" ENSG00000288529 ENSG00000288529 "Novel protein" 6 133953304-133980088 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 2.9;Uterine Corpus Endometrial Carcinoma (TCGA): 2.8" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "unprognostic (2.66e-1)" "unprognostic (2.04e-1)" ENSG00000288570 ENSG00000288570 "Novel protein" 9 130713626-130713724 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "stomach 1: 1.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Skin Cutaneous Melanoma (TCGA): 2.9" "Region enriched" "Detected in single" 52 "cerebral cortex: 5.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "head and neck cancer: 1.2" NA NA "Cluster 42: Retina - Visual perception" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 61: BICR 18 - Protein kinases" "unprognostic (2.79e-1)" ENSG00000288593 ENSG00000288593 "Novel protein" 21 43939919-43959673 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 18 "retina: 15.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 42: Retina - Visual perception" "Cluster 6: Non-specific - Immune response" "Cluster 55: Lymphoma - Immune response" ENSG00000288608 ENSG00000288608 "Novel protein" 7 151061928-151061978 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 9 "Kidney Renal Papillary Cell Carcinoma (TCGA): 2.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA ENSG00000288614 ENSG00000288614 "Novel protein" 6 53041266-53041385 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder Urothelial Carcinoma (TCGA): 1.2" "Group enriched" "Detected in some" 6 "cerebral cortex: 9.6;medulla oblongata: 3.7;pons: 3.6" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in single" 9 "head and neck cancer: 1.5" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 74: Non-specific - Signal transduction" "Cluster 37: Neurons - Mixed function" "Cluster 61: BICR 18 - Protein kinases" "unprognostic (4.39e-1)" ENSG00000288623 ENSG00000288623 "Novel protein" 12 120534697-120534957 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "skeletal muscle: 11.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 10.9;Stomach Adenocarcinoma (TCGA): 15.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 23.4" "Lineage enriched" "Detected in all" 5 "granulocytes: 23.4" "Low cancer specificity" "Detected in many" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 18: Non-specific - Mixed function" "Cluster 61: BICR 18 - Protein kinases" "unprognostic (2.17e-1)" "unprognostic (6.85e-2)" "unprognostic (2.68e-2)" ENSG00000288625 ENSG00000288625 "Novel protein" 15 81002142-81002279 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "kidney: 2.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Stomach Adenocarcinoma (TCGA): 1.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 14: Neurons - Synaptic function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (1.11e-2)" ENSG00000288626 ENSG00000288626 "Novel protein" 1 147611590-147611796 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "adipose tissue: 1.2;skeletal muscle: 1.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Kidney Chromophobe (TCGA): 3.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 61: BICR 18 - Protein kinases" ENSG00000288629 ENSG00000288629 "Novel protein" 1 89579592-89579654 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 13 "Bladder Urothelial Carcinoma (TCGA): 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 51: Myeloma - Immunoglobulins" ENSG00000288634 ENSG00000288634 "Novel protein" 7 112450487-112450645 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "bone marrow: 25.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 61: BICR 18 - Protein kinases" "unprognostic (6.07e-1)" "unprognostic (1.53e-1)" "unprognostic (4.20e-1)" "unprognostic (1.78e-1)" "unprognostic (2.47e-1)" "unprognostic (2.05e-2)" "unprognostic (2.81e-1)" ENSG00000288635 ENSG00000288635 "Novel protein, readthrough ST7-OT4 - ST7" 7 116954391-117119719 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "testis: 12.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 39: Astrocytes - Mixed function" "Cluster 39: Non-specific - Transcription" "unprognostic (2.59e-1)" "unprognostic (2.02e-1)" "unprognostic (9.93e-2)" "unprognostic (1.56e-1)" "unprognostic (4.54e-2)" "unprognostic (1.49e-2)" "unprognostic (1.62e-1)" "unprognostic (8.98e-2)" ENSG00000288636 ENSG00000288636 "Novel protein" 1 17005068-17011757 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "intestine: 1.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 2.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 63: Non-specific - Basic cellular processes" "Cluster 44: Connective tissue cells - ECM organization" "unprognostic (5.49e-1)" ENSG00000288637 ENSG00000288637 "Novel protein" 4 153152435-153415081 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 6.8;Endometrial glandular cells: 5.0;Endometrial luminal cells: 11.7;Oocytes: 9.2;Retinal horizontal cells: 4.0;Tuft cells: 23.1" "Cancer enhanced" "Detected in single" "Kidney Chromophobe (TCGA): 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 4.2" "HPA035853, HPA035854, HPA043499" Uncertain Approved Centrosome NA NA "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" Centrosome "HPA035853: , HPA035854: , HPA043499: " "unprognostic (3.05e-1)" "potential prognostic unfavorable (9.06e-4)" "unprognostic (7.37e-2)" ENSG00000288644 ENSG00000288644 "Novel protein" 1 203802094-203802192 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder Urothelial Carcinoma (TCGA): 1.4;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 1.3" "Group enriched" "Detected in some" 44 "cerebral cortex: 6.4;pons: 2.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 51: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "unprognostic (6.65e-2)" "unprognostic (5.01e-2)" ENSG00000288645 ENSG00000288645 "Novel protein" 15 50648802-50686717 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 1.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 20: Myeloma - Immune response" ENSG00000288646 ENSG00000288646 "Novel protein" 6 53065602-53065673 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 1.8;Uterine Corpus Endometrial Carcinoma (TCGA): 1.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 34: B-cells - Unknown function" ENSG00000288654 ENSG00000288654 "Novel protein" 3 88058139-88058216 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 47 "skeletal muscle: 4.7" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder Urothelial Carcinoma (TCGA): 6.1;Testicular Germ Cell Tumor (TCGA): 12.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" ENSG00000288658 ENSG00000288658 "Novel protein, ortholog of Gm2102 (M. musculus)" 2 222314148-222320155 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 5.0" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 10.6;Decidual stromal cells: 3.5;Endometrial stromal cells: 3.0;monocytes: 2.2;Myosatellite cells: 2.3;Pancreatic islet cells: 3.4;Respiratory ionocytes: 2.5;Thymic myoid cells: 5.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Neuroblastoma: 1.3" "Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" "unprognostic (3.41e-1)" "unprognostic (2.09e-3)" "unprognostic (2.66e-2)" "unprognostic (1.55e-1)" ENSG00000288661 ENSG00000288661 "Novel protein" X 63754485-63754664 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "blood vessel: 3.9" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in single" "testis cancer: 1.1" NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 61: BICR 18 - Protein kinases" "unprognostic (1.61e-1)" "unprognostic (2.72e-1)" "unprognostic (3.30e-1)" ENSG00000288671 ENSG00000288671 "Novel protein" 19 42215133-42232149 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 21.3;Epicardial cells: 13.6" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" ENSG00000288678 ENSG00000288678 "Novel protein" 1 31919563-31919628 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder Urothelial Carcinoma (TCGA): 1.8;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 1.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 12 "head and neck cancer: 1.1" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 61: BICR 18 - Protein kinases" ENSG00000288681 ENSG00000288681 "Novel protein" 11 308408-315272 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in many" 8 "Neutrophils: 119.3" "Group enriched" "Detected in many" 7 "Ovary Serous Cystadenocarcinoma (TCGA): 136.5;Stomach Adenocarcinoma (TCGA): 81.0;Uterine Corpus Endometrial Carcinoma (TCGA): 38.1" "Group enriched" "Detected in some" 6 "cerebral cortex: 7.6;hippocampal formation: 3.6" "Immune cell enhanced" "Detected in all" "neutrophil: 488.7" "Lineage enriched" "Detected in all" 6 "granulocytes: 488.7" "Cancer enriched" "Detected in single" 59 "Bile duct cancer: 7.9" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 24: Neutrophils - Innate immunity signal integration" "unprognostic (1.18e-1)" "unprognostic (3.50e-3)" "potential prognostic unfavorable (5.19e-4)" "unprognostic (3.16e-1)" ENSG00000288684 ENSG00000288684 "Novel protein" 9 32455323-32552603 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 5.4" "Lineage enriched" "Detected in single" 7 "granulocytes: 5.4" "Low cancer specificity" "Detected in single" "HPA047193, HPA073217" Uncertain Approved "Plasma membrane,Cytosol" No NA "Cluster 35: Neutrophils - Protein binding" "Cluster 27: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 20: Non-specific - Transcription regulation" "Plasma membrane, Cytosol" "HPA047193: , HPA073217: " "unprognostic (2.76e-2)" ENSG00000288695 ENSG00000288695 "Novel protein, SRD5A3-RP11-177J6.1 readthrough" 4 55346228-55388368 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 2.2;skeletal muscle: 2.8" "Cell type enhanced" "Detected in some" "Endometrial glandular cells: 2.7;Foveolar cells: 1.0;Gastric progenitor cells: 1.3;pDCs: 1.8;Respiratory deuterosomal cells: 1.0;Retinal amacrine cells: 1.4;Schwann cells: 1.1;Thymic myoid cells: 1.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 51: Secretory epithelial cells - Mixed function" "unprognostic (1.54e-1)" "unprognostic (4.18e-2)" ENSG00000288706 ENSG00000288706 "Novel protein" X 23783278-23783367 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 29 "head and neck cancer: 5.8" NA NA "Cluster 61: BICR 18 - Protein kinases" ENSG00000288708 ENSG00000288708 "Novel protein" 6 16328342-16328431 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 22 "lymphoid tissue: 3.1;skeletal muscle: 6.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 17: Neuroblastoma - Neuronal signaling" ENSG00000288712 ENSG00000288712 "Novel protein" 6 68635890-68635967 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 33: Sarcoma - Muscle contraction" ENSG00000288715 ENSG00000288715 "Novel protein" 16 89317046-89418292 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 14 "neutrophil: 1.3" "Lineage enriched" "Detected in single" 14 "granulocytes: 1.3" "Not detected" "Not detected" NA NA "Cluster 4: Neutrophils - Degranulation" ENSG00000288716 ENSG00000288716 "Novel protein" 13 77326905-77326988 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "bone marrow: 9.7;retina: 2.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 5.7" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 15: Bone marrow - Innate immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" ENSG00000288796 ENSG00000288796 "Novel protein" 4 73981074-73988190 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "bone marrow: 15.4" "Group enriched" "Detected in some" 72 "Megakaryocytes: 1112.7;Platelets: 2444.8" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 10 "basophil: 174.4;neutrophil: 71.6" "Lineage enriched" "Detected in many" 14 "granulocytes: 174.4" "Not detected" "Not detected" "HPA008354, HPA052485" Supported NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 47: Platelets - Hemostasis" "HPA008354: , HPA052485: " ENSG00000288841 ENSG00000288841 "Novel protein" 9 131432759-131446473 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 3.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 65: Brain - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 61: BICR 18 - Protein kinases" ENSG00000288914 ENSG00000288914 "Novel protein" 7 105040858-105040956 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA ENSG00000289025 ENSG00000289025 "Novel protein" 15 52045846-52045899 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: BICR 18 - Protein kinases" ENSG00000289027 ENSG00000289027 "Novel protein" 7 92112176-92245924 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "testis cancer: 10.9" "HPA041325, HPA043508, HPA049606" Uncertain Approved "Endoplasmic reticulum,Vesicles" NA NA "Cluster 33: Thyroid gland - Tissue development" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" "Endoplasmic reticulum, Vesicles" "HPA041325: , HPA043508: , HPA049606: " ENSG00000289051 ENSG00000289051 "Novel protein" C0HLV8 10 87863559-87863654 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 72: Neuronal - Signal transduction" ENSG00000289258 ENSG00000289258 "Novel protein" 10 86654518-86700020 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 34 "Cardiomyocytes: 13.3" "Region enhanced" "Detected in single" "basal ganglia: 1.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA039147, HPA048955" Uncertain Approved "Nucleoplasm,Focal adhesion sites,Cytosol" NA NA "Cluster 33: Neurons - Mixed function" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" "Focal adhesion sites" "Nucleoplasm, Cytosol" "HPA039147: , HPA048955: " ENSG00000289281 ENSG00000289281 "Novel protein" 16 3004132-3004859 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 1.0;Corticotrophs: 2.0;Neutrophils: 1.5;Pancreatic duct cells: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 37: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 48: Neutrophils - Phagocytosis & degranulation" ENSG00000289282 ENSG00000289282 "Novel protein" 6 31623874-31625499 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "esophagus: 8.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 61: BICR 18 - Protein kinases" ENSG00000289325 ENSG00000289325 "Novel protein" 10 66926308-66926346 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA ENSG00000289346 ENSG00000289346 "Novel protein" 7 74796150-74890585 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA056679, HPA056680" Approved Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 6: Non-specific - Immune response" "Cluster 39: Non-specific - Transcription" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" Nucleoplasm "HPA056679: , HPA056680: " ENSG00000289360 ENSG00000289360 "Novel protein" 7 105040848-105040925 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA ENSG00000289490 ENSG00000289490 "Novel protein" 2 202377112-202377168 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 45 "skeletal muscle: 4.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 30: Skeletal muscle - Striated muscle contraction" ENSG00000289491 ENSG00000289491 "Novel protein" C0HLU2 16 30610211-30610351 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 1.9;choroid plexus: 1.5;intestine: 1.7;lymphoid tissue: 1.4;skeletal muscle: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" ENSG00000289653 ENSG00000289653 "Novel protein" 8 102858046-102863860 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 4 "skeletal muscle: 1.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 36: Choroid plexus - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" ENSG00000289690 ENSG00000289690 "Novel transcript" 7 100397577-100434107 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "bone marrow: 2.0" "Cell type enhanced" "Detected in some" "Adipocytes: 6.3;Cardiomyocytes: 23.2;Early primary spermatocytes: 10.2;Epicardial cells: 11.4;monocytes: 13.7;Neutrophils: 30.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.6" "Group enriched" "Detected in many" 5 "dendritic cells: 2.7;granulocytes: 4.6;monocytes: 1.5" "Not detected" "Not detected" HPA051587 Uncertain NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 15: Bone marrow - Innate immune response" "Cluster 35: Non-specific - DNA binding" "Cluster 56: Non-specific - Sensory perception" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" "HPA051587: " ENSG00000289692 ENSG00000289692 "Novel protein" 1 22636506-22644067 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 18.1;lymphoid tissue: 16.3" "Group enriched" "Detected in some" 4 "Hofbauer cells: 6.5;Kupffer cells: 15.4;Macrophages: 7.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 38 "intermediate monocyte: 10.7;non-classical monocyte: 9.5" "Lineage enriched" "Detected in single" 48 "monocytes: 10.7" "Not detected" "Not detected" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 1: Neuronal - Visual perception" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" ENSG00000289694 ENSG00000289694 "Novel protein" 1 22025142-22092943 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "cDC: 9.3;Epicardial cells: 13.6;Hofbauer cells: 12.3;Innate lymphoid cells: 9.1;Monocyte progenitors: 11.0;Paneth cells: 11.6;pDCs: 9.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA069590 Approved NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "HPA069590: " ENSG00000289697 ENSG00000289697 "Novel protein" 1 196651852-196795393 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "liver: 158.5" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 1.5;Epicardial cells: 2.3;Epididymal basal cells: 1.4;Fibro-adipogenic progenitors: 1.5;Fibroblasts: 3.0;Hepatocytes: 2.4;Mesothelial cells: 4.4;Peritubular myoid cells: 1.2;Respiratory deuterosomal cells: 3.1;Salivary basal cells: 1.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 16.0" "HPA049176, HPA053326" Uncertain NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 8: Immune cells - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 103: Non-specific - Basic cellular processes" "HPA049176: , HPA053326: " ENSG00000289700 ENSG00000289700 "Novel protein" 1 209779629-209806179 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 1.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 23.1;Endometrial ciliated cells: 22.8;Endometrial glandular cells: 22.9;Endometrial luminal cells: 45.9;Esophageal apical cells: 27.6;Esophageal basal cells: 24.7;Esophageal suprabasal cells: 35.4;Ocular epithelial cells: 61.5;Salivary basal cells: 29.8;Suprabasal keratinocytes: 39.2;Urothelial cells: 41.2" "Region enhanced" "Detected in single" "cerebellum: 1.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 7.9;head and neck cancer: 9.3" "HPA063121, HPA076162" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 35: Non-specific - DNA binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" Cytosol Nucleoplasm "HPA063121: , HPA076162: " ENSG00000289710 ENSG00000289710 "Novel protein, similar to CD24 molecule CD52" 1 30576655-30576825 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in some" "midbrain: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 49: Hindbrain - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" ENSG00000289715 ENSG00000289715 "Novel protein" 1 21547404-21554002 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 57 "retina: 21.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 28 "neutrophil: 2.7" "Lineage enriched" "Detected in single" 28 "granulocytes: 2.7" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 42: Retina - Visual perception" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 71: Lymphoma - Inflammatory response" ENSG00000289722 ENSG00000289722 "Novel protein" 16 1833987-1884294 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 18 "testis: 9.0" "Cell type enhanced" "Detected in single" "Early primary spermatocytes: 2.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 3: Early primary spermatocytes - Early meiosis" ENSG00000289723 ENSG00000289723 "Novel T cell receptor alpha variable" 14 21861353-21862012 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "fallopian tube: 7.6;lymphoid tissue: 13.0" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.2" "Group enriched" "Detected in many" 28 "MAIT T-cell: 8.4;memory CD4 T-cell: 16.5;memory CD8 T-cell: 13.1;naive CD4 T-cell: 19.3;naive CD8 T-cell: 13.9;T-reg: 20.8" "Lineage enriched" "Detected in single" 38 "T-cells: 20.8" "Not detected" "Not detected" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 53: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" ENSG00000289724 ENSG00000289724 "Novel protein, SERPINB2-SERPINB10 readthrough" 18 63897174-63917490 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 7.3;Conjunctival goblet cells: 1.9;Epicardial cells: 2.3;Esophageal apical cells: 5.4;Monocyte progenitors: 1.9;monocytes: 18.2;Neutrophil progenitors: 2.3;Ocular epithelial cells: 6.9;Syncytiotrophoblasts: 2.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA015480 Uncertain NA NA "Cluster 64: Connective tissue cells - ECM organization" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" "HPA015480: " ENSG00000289747 ENSG00000289747 "Novel protein" 3 195908695-195909561 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 1.2;skeletal muscle: 3.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 51: Neurons - Mixed function" "Cluster 40: Non-specific - Unknown function" ENSG00000289760 ENSG00000289760 "Novel protein" 7 100478099-100478170 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 33: Non-specific - ATP binding" ENSG00000289761 ENSG00000289761 "Novel protein" 4 41143022-41143099 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA ENSG00000289763 ENSG00000289763 "Novel protein" 3 10249042-10249366 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Sarcoma: 1.6" "Not detected" "Not detected" NA NA "Cluster 5: Spleen - Immune response" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 61: BICR 18 - Protein kinases" ENSG00000289764 ENSG00000289764 "Novel protein" 17 80545075-80545134 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 15: NK-cells - Unknown function" ENSG00000289766 ENSG00000289766 "Novel protein" 12 13088784-13103484 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 1: Neuronal - Visual perception" ENSG00000289767 ENSG00000289767 "Novel protein" 8 109539726-109539800 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 7 "skeletal muscle: 8.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 61: BICR 18 - Protein kinases" ENSG00000289768 ENSG00000289768 "Novel protein similar to Fc fragment of IgG, low affinity III, receptor (CD16a) proteins" 1 161544807-161631456 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 12.4" "Group enriched" "Detected in some" 4 "cDC: 69.5;Epicardial cells: 34.1;Macrophages: 129.2;Neutrophils: 44.1" "Group enriched" "Detected in some" 4 "cerebral cortex: 1.8;medulla oblongata: 1.1;pons: 1.7" "Immune cell enriched" "Detected in many" 35 "neutrophil: 1484.3" "Lineage enriched" "Detected in many" 35 "granulocytes: 1484.3" "Not detected" "Not detected" NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" ENSG00000289791 ENSG00000289791 "Novel protein" 5 33997007-34008084 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "adipose tissue: 1.1;liver: 1.0;prostate: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Kidney cancer: 6.1" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" ENSG00000289809 ENSG00000289809 "Novel protein" 3 12825768-12871919 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "adipose tissue: 4.3;testis: 9.5" "Cell type enhanced" "Detected in many" "B-cells: 115.2;Cardiomyocytes: 105.0;Epicardial cells: 220.6;Medullary thymic epithelial cells: 55.2;Mesothelial cells: 378.6;Plasma cells: 126.2;T-cells: 74.3;Thymocytes: 249.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 8: Immune cells - Immune response" "Cluster 35: RS4;11 - Unknown function" "Cluster 9: T-cells - Adaptive immunity: Regulation" ENSG00000290147 ENSG00000290147 "Novel protein" P43080 6 42155406-42180056 "Disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "retina: 43.9" "Group enriched" "Detected in some" 16 "Early spermatids: 45.3;Late spermatids: 164.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA005561, HPA075056" Supported Uncertain "Plasma membrane" NA NA "Cluster 42: Retina - Visual perception" "Cluster 1: Neuronal - Visual perception" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 7 "Plasma membrane" "HPA005561: , HPA075056: " ENSG00000290149 ENSG00000290149 "Novel protein, GPR141-NME8-EPDR1 readthrough" 7 37683843-37950412 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 4 "skeletal muscle: 1.2" "Cell type enhanced" "Detected in some" "cDC: 19.4;Endometrial stromal cells: 21.0;Mast cells: 33.5;Neutrophil progenitors: 138.2;Neutrophils: 101.4;NK-cells: 38.3;pDCs: 88.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 48: Neutrophils - Phagocytosis & degranulation" ENSG00000290183 ENSG00000290183 "Novel protein" 16 3263800-3291029 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 19.3;Medullary thymic epithelial cells: 24.0;Neutrophil progenitors: 36.0;Neutrophils: 108.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 2: Neurons - Nucleosome" "Cluster 54: Non-specific - Transcription" "Cluster 24: Neutrophils - Innate immunity signal integration" ENSG00000290184 ENSG00000290184 "Novel protein" X 49258343-49270477 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "epididymis: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 17 "T-reg: 2.0" "Lineage enriched" "Detected in single" 21 "T-cells: 2.0" "Not detected" "Not detected" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 51: Myeloma - Immunoglobulins" ENSG00000290217 ENSG00000290217 "Novel protein" 6 25652210-25738044 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 12 "testis: 3.8" "Group enriched" "Detected in some" 4 "Differentiating spermatogonia: 19.7;Early primary spermatocytes: 56.9;Late primary spermatocytes: 77.2;Late spermatids: 34.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 106: Spermatogonia - Spermatogonial differentiation" ENSG00000290315 ENSG00000290315 "Novel protein" 3 49024345-49094071 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "pons: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001400, HPA037677, HPA037678" Uncertain Approved "Nucleoplasm,Cytosol,Rods & Rings" NA NA "Cluster 45: Non-specific - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "Nucleoplasm, Cytosol, Rods & Rings" "HPA001400: , HPA037677: , HPA037678: " ENSG00000290316 ENSG00000290316 "Novel protein, CYP4V2-KLKB1 readthrough" 4 186208979-186258469 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "retina: 1.2" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 14.8;Adrenal medulla cells: 10.6;Corticotrophs: 10.0;Epididymal clear cells: 8.2;Lactotrophs: 14.7;Müller glia: 15.3;Pituicytes/FSCs: 17.1;Pituitary stem cells: 8.4" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 3: Choroid plexus - Cilium" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" ENSG00000290317 ENSG00000290317 "Novel protein, ACKR2-ZNF662-KRBOX1 readthrough" C9JBD0 3 42809483-42942792 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "placenta: 1.2" "Cell type enhanced" "Detected in some" "Early primary spermatocytes: 1.1;Late primary spermatocytes: 2.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA046901 Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" Nucleoplasm "Golgi apparatus" "HPA046901: " ENSG00000290318 ENSG00000290318 "Novel protein" 3 49357176-49412051 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Colonocytes: 5.6;Enteric stem cells: 3.6;Enteric transient amplifying cells: 5.9;Enterocytes: 5.1;Epididymal clear cells: 6.1;Gastric chief cells: 4.4;Goblet cells: 3.3;Kupffer cells: 6.1;Megakaryocytes: 6.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 15: Non-specific - Protein processing" ENSG00000291239 ENSG00000291239 "Novel protein" 19 36850858-36998682 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Cardiomyocytes: 9.0;Epicardial cells: 13.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" ENSG00000291302 ENSG00000291302 "Novel protein" 6 31622774-31622860 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 20: Non-specific - DNA binding" ENSG00000291303 ENSG00000291303 "Novel protein" 9 131430129-131430218 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.2" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" NA NA "Cluster 24: Non-specific - Transcription" ENSG00000291312 ENSG00000291312 "Novel protein" 19 39830482-39831956 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" ENSG00000291313 ENSG00000291313 "Novel protein" 14 103334237-103335932 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "adipose tissue: 2.1;brain: 1.0;stomach 1: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 27: Non-specific - Mixed function" "Cluster 40: Non-specific - Unknown function" ENSG00000291314 ENSG00000291314 "Novel protein" X 10566888-10576955 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 19: Astrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" ENSG00000291315 ENSG00000291315 "Novel protein" 3 40312086-40312214 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 15 "skeletal muscle: 37.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 20: Myeloma - Immune response" ENSG00000291316 ENSG00000291316 "Novel protein, LOC84773-CYHR1 readthrough" Q6ZMK1 8 144449582-144465430 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in single" "Thymic myoid cells: 1.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053653, HPA059543" Approved Approved Nucleoplasm NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 51: Neurons - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 2 Nucleoplasm "HPA053653: , HPA059543: " ENTHD1 FLJ25421 ENSG00000176177 "ENTH domain containing 1" Q8IYW4 22 39743044-39893864 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 10.3" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 227.0;Early primary spermatocytes: 125.1;Early spermatids: 32.6;Epicardial cells: 31.8;Late primary spermatocytes: 47.5;Late spermatids: 26.8;Mast cells: 29.6;Sertoli cells: 52.9;Thymic myoid cells: 27.2" "Cell type enhanced" "Detected in some" "medium spiny neuron: 8.3" "Cancer enriched" "Detected in single" 30 "Skin Cutaneous Melanoma (TCGA): 12.1" "Region enriched" "Detected in single" 6 "basal ganglia: 1.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "skin cancer: 3.4" "Testis - Early spermatids, Testis - Spermatocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA019800 Uncertain NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 33: Neurons - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 3 "HPA019800: " "unprognostic (3.02e-1)" "unprognostic (7.32e-2)" ENTPD1 "ATPDase, CD39, NTPDase-1, SPG64" ENSG00000138185 "Ectonucleoside triphosphate diphosphohydrolase 1" P49961 10 95711779-95877266 "CD markers, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" Hydrolase "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "cDC: 342.1;Macrophages: 197.7;Microglia: 633.7;monocytes: 138.4;Neutrophil progenitors: 989.1;Neutrophils: 978.4;Vascular endothelial cells: 141.4" "Group enriched" "Detected in all" 4 "central nervous system macrophage: 763.4;endothelial cell: 342.1;vascular associated smooth muscle cell: 240.7" "Cancer enhanced" "Detected in all" "Thyroid Carcinoma (TCGA): 71.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 102.4" "Group enriched" "Detected in all" 4 "dendritic cells: 31.9;granulocytes: 102.4;monocytes: 41.0" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002494, HPA014067, CAB079986" Enhanced Uncertain Microtubules NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 3 Microtubules "CAB002494: , CAB079986: , HPA014067: " "unprognostic (2.22e-2)" "unprognostic (3.00e-1)" "unprognostic (1.79e-1)" "unprognostic (1.28e-1)" "unprognostic (1.29e-1)" "unprognostic (3.12e-2)" "unprognostic (1.12e-1)" "unprognostic (3.99e-2)" "unprognostic (6.37e-3)" "unprognostic (8.45e-2)" "validated prognostic favorable (3.00e-6)" "validated prognostic favorable (3.51e-4)" "unprognostic (2.65e-2)" "unprognostic (5.53e-2)" "unprognostic (2.83e-1)" "potential prognostic favorable (4.08e-4)" "unprognostic (1.59e-1)" "unprognostic (5.19e-2)" "unprognostic (2.77e-2)" "potential prognostic unfavorable (2.98e-4)" "unprognostic (1.28e-3)" "unprognostic (2.69e-1)" "unprognostic (2.02e-2)" "unprognostic (1.39e-1)" "unprognostic (1.43e-1)" "potential prognostic favorable (1.44e-4)" "unprognostic (3.27e-2)" "unprognostic (2.57e-2)" "unprognostic (1.30e-1)" "unprognostic (6.70e-3)" "unprognostic (2.58e-1)" ENTPD2 "CD39L1, NTPDase-2" ENSG00000054179 "Ectonucleoside triphosphate diphosphohydrolase 2" Q9Y5L3 9 137048107-137054061 "Metabolic proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 44.3;Breast myoepithelial cells: 32.7;Colonocytes: 26.1;Enterocytes: 55.9;Ependymal cells: 77.5;Leydig cells: 204.1;Peritubular myoid cells: 98.8;Schwann cells: 63.3" "Group enriched" "Detected in many" 7 "astrocyte: 63.0;ependymal cell: 104.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 15.3" "Adipose subcutaneous - Smooth muscle cells, Minor Salivary Gland - Smooth muscle cells, Prostate - Prostate glandular cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017676 Approved NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 39: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 94: Gonadal somatic cells - Mixed function" 2 "HPA017676: " "unprognostic (1.10e-1)" "unprognostic (1.73e-1)" "unprognostic (1.18e-1)" "unprognostic (1.41e-1)" "unprognostic (2.68e-1)" "unprognostic (5.70e-2)" "unprognostic (1.03e-2)" "unprognostic (1.50e-3)" "unprognostic (9.64e-2)" "unprognostic (8.45e-2)" "potential prognostic favorable (1.63e-5)" "unprognostic (4.21e-2)" "potential prognostic favorable (3.79e-4)" "potential prognostic unfavorable (2.57e-5)" "unprognostic (5.99e-3)" "potential prognostic unfavorable (7.45e-4)" "unprognostic (2.04e-1)" "unprognostic (1.03e-1)" "unprognostic (2.04e-1)" "unprognostic (2.50e-1)" "unprognostic (2.62e-1)" "unprognostic (1.61e-1)" "unprognostic (4.83e-2)" "unprognostic (2.46e-1)" "unprognostic (1.30e-1)" "unprognostic (3.13e-2)" "unprognostic (2.84e-1)" "potential prognostic favorable (5.73e-4)" "unprognostic (1.86e-1)" "unprognostic (1.27e-1)" "unprognostic (1.30e-1)" ENTPD3 "CD39L3, HB6, NTPDase-3" ENSG00000168032 "Ectonucleoside triphosphate diphosphohydrolase 3" O75355 3 40387184-40428744 "Enzymes, Metabolic proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.3;cervix: 20.1;salivary gland: 20.8" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 113.8;Breast lactating cells: 93.2;Cardiomyocytes: 88.7;Endometrial glandular cells: 57.8;Lacrimal acinar cells: 50.7;Retinal ganglion cells: 77.3;Urothelial cells: 132.8" "Cell type enhanced" "Detected in all" "CGE interneuron: 185.4;medium spiny neuron: 221.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "plasmacytoid DC: 3.5" "Lineage enriched" "Detected in single" 7 "dendritic cells: 3.5" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 18.5" "Colon - Colon enteroendocrine cells, Heart muscle - Smooth muscle cells, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Skin - Inner root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071802 Approved Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 36: Brain & Liver - Signaling" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 69: Urothelial cells - Basic cellular functions" 1 Cytosol "HPA071802: " "unprognostic (1.17e-2)" "unprognostic (8.44e-2)" "unprognostic (1.46e-1)" "unprognostic (3.76e-3)" "unprognostic (8.82e-2)" "unprognostic (1.58e-1)" "unprognostic (8.17e-2)" "unprognostic (8.19e-2)" "unprognostic (2.09e-2)" "unprognostic (3.43e-2)" "unprognostic (1.89e-1)" "unprognostic (3.55e-2)" "unprognostic (6.27e-3)" "unprognostic (1.06e-2)" "unprognostic (7.60e-2)" "unprognostic (1.00e-1)" "potential prognostic favorable (3.41e-5)" "unprognostic (1.88e-1)" "unprognostic (3.89e-1)" "unprognostic (7.58e-2)" "unprognostic (8.25e-2)" "unprognostic (3.45e-1)" "unprognostic (2.09e-1)" "unprognostic (9.83e-3)" ENTPD4 "KIAA0392, LALP70, LAP70, LYSAL1, NTPDase-4, UDPase" ENSG00000197217 "Ectonucleoside triphosphate diphosphohydrolase 4" Q9Y227 8 23385783-23457695 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017655 Supported Approved Vesicles NA NA 78000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 5 Vesicles "HPA017655: " "potential prognostic favorable (3.78e-4)" "unprognostic (1.38e-1)" "potential prognostic favorable (9.59e-4)" "unprognostic (1.32e-1)" "unprognostic (4.26e-3)" "unprognostic (3.22e-1)" "unprognostic (9.81e-2)" "unprognostic (1.93e-3)" "unprognostic (6.27e-3)" "unprognostic (6.82e-3)" "unprognostic (8.19e-2)" "unprognostic (2.87e-1)" "unprognostic (1.12e-1)" "unprognostic (4.12e-2)" "unprognostic (4.98e-2)" "unprognostic (8.22e-2)" "unprognostic (4.39e-1)" "unprognostic (2.29e-1)" "unprognostic (4.27e-2)" "unprognostic (4.66e-2)" "unprognostic (2.54e-2)" "unprognostic (3.01e-1)" "unprognostic (3.37e-3)" "unprognostic (1.86e-1)" "unprognostic (4.68e-2)" "unprognostic (1.70e-1)" "unprognostic (2.46e-1)" "unprognostic (2.89e-1)" "unprognostic (2.91e-1)" "unprognostic (7.48e-2)" "unprognostic (1.18e-1)" ENTPD5 "CD39L4, NTPDase-5, PCPH" ENSG00000187097 "Ectonucleoside triphosphate diphosphohydrolase 5 (inactive)" O75356 14 73958010-74019399 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 100.7;kidney: 88.8;liver: 246.5" "Cell type enhanced" "Detected in many" "Colonocytes: 187.5;Goblet cells: 127.2;Hepatocytes: 163.8;Prostatic club cells: 252.8;Prostatic glandular cells: 142.2;Proximal tubule cells: 114.1" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Liver Hepatocellular Carcinoma (TCGA): 58.9;Prostate Adenocarcinoma (TCGA): 150.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 18.4;eosinophil: 9.4" "Lineage enriched" "Detected in many" 7 "granulocytes: 18.4" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Stomach - Gastric mucous cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002927 Enhanced "Secreted to blood" Enzyme NA NA 5800000 "Cluster 46: Basophils - Proteolysis" "Cluster 76: Non-specific - Metabolism" "Cluster 30: White matter - Myelination" "Cluster 18: Liver cancer - Metabolism" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 3 "HPA002927: " "unprognostic (4.41e-1)" "unprognostic (2.69e-1)" "unprognostic (4.49e-2)" "unprognostic (5.05e-3)" "unprognostic (3.55e-2)" "unprognostic (1.02e-2)" "unprognostic (3.28e-1)" "unprognostic (2.12e-3)" "unprognostic (1.25e-2)" "unprognostic (1.21e-3)" "potential prognostic favorable (9.70e-7)" "unprognostic (8.50e-3)" "unprognostic (1.19e-2)" "unprognostic (4.67e-2)" "unprognostic (5.55e-2)" "unprognostic (5.43e-2)" "unprognostic (1.18e-1)" "unprognostic (2.05e-2)" "unprognostic (3.19e-1)" "unprognostic (2.17e-1)" "unprognostic (8.97e-2)" "unprognostic (6.59e-2)" "unprognostic (1.07e-1)" "unprognostic (4.61e-2)" "unprognostic (3.58e-2)" "unprognostic (2.11e-3)" "unprognostic (8.32e-2)" "unprognostic (6.42e-2)" "unprognostic (2.10e-2)" "unprognostic (2.38e-1)" "unprognostic (4.47e-1)" ENTPD6 "CD39L2, dJ738P15.3, IL6ST2, NTPDase-6" ENSG00000197586 "Ectonucleoside triphosphate diphosphohydrolase 6" O75354 20 25195693-25228075 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 115.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015491, HPA069555" Approved Supported "Golgi apparatus" "Secreted to blood" Enzyme NA NA 38000 "Cluster 13: Non-specific - Mitochondria" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 33: Neurons - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 3 "Golgi apparatus" "HPA015491: , HPA069555: " "unprognostic (8.22e-2)" "unprognostic (1.02e-1)" "unprognostic (4.36e-2)" "unprognostic (4.93e-3)" "unprognostic (2.56e-2)" "unprognostic (4.86e-2)" "unprognostic (4.39e-2)" "unprognostic (2.03e-2)" "unprognostic (1.84e-1)" "unprognostic (7.67e-2)" "unprognostic (4.26e-3)" "unprognostic (2.37e-3)" "unprognostic (7.30e-2)" "potential prognostic unfavorable (8.82e-4)" "unprognostic (4.96e-3)" "unprognostic (1.08e-2)" "unprognostic (4.42e-2)" "unprognostic (1.06e-2)" "unprognostic (2.38e-1)" "unprognostic (4.00e-2)" "unprognostic (1.33e-1)" "unprognostic (2.01e-1)" "unprognostic (9.24e-2)" "unprognostic (1.52e-1)" "unprognostic (1.61e-3)" "unprognostic (2.83e-1)" "unprognostic (4.51e-2)" "unprognostic (2.86e-3)" "unprognostic (1.31e-1)" "unprognostic (3.02e-1)" "unprognostic (3.48e-2)" ENTPD7 "FLJ30978, LALP1" ENSG00000198018 "Ectonucleoside triphosphate diphosphohydrolase 7" Q9NQZ7 10 99659509-99711241 "Enzymes, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 13.8" "Cell type enhanced" "Detected in many" "Endometrial secretory cells: 68.1;Enterocytes: 93.4;Epididymal basal cells: 74.6;Ocular epithelial cells: 120.4;Urothelial cells: 193.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014351 Uncertain Approved Nucleoplasm NA NA 18000 "Cluster 13: Non-specific - Mitochondria" "Cluster 77: Intestine - Digestion" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 15: Kidney cancer - Membrane components" "Cluster 69: Urothelial cells - Basic cellular functions" 15 Nucleoplasm "HPA014351: " "unprognostic (8.02e-2)" "unprognostic (1.82e-1)" "unprognostic (2.15e-1)" "unprognostic (9.99e-2)" "unprognostic (1.57e-2)" "unprognostic (7.65e-2)" "unprognostic (9.18e-2)" "unprognostic (1.24e-1)" "unprognostic (3.76e-3)" "unprognostic (1.75e-3)" "unprognostic (2.14e-1)" "unprognostic (1.63e-1)" "unprognostic (1.98e-1)" "unprognostic (2.47e-2)" "unprognostic (3.01e-3)" "unprognostic (1.69e-2)" "unprognostic (1.84e-1)" "unprognostic (2.71e-1)" "unprognostic (3.82e-2)" "unprognostic (5.15e-3)" "unprognostic (4.50e-3)" "unprognostic (1.77e-1)" "unprognostic (4.71e-2)" "unprognostic (1.73e-1)" "unprognostic (3.36e-2)" "unprognostic (7.13e-2)" "unprognostic (5.51e-2)" "unprognostic (1.85e-1)" "unprognostic (4.00e-3)" "unprognostic (8.99e-3)" ENTPD8 "NTPDase-8, UNQ2492" ENSG00000188833 "Ectonucleoside triphosphate diphosphohydrolase 8" Q5MY95 9 137434364-137441816 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 26.0;liver: 15.0" "Group enriched" "Detected in some" 8 "Colonocytes: 125.7;Enterocytes: 167.2;Goblet cells: 243.0" "Cell type enhanced" "Detected in single" "ependymal cell: 1.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 5.2" "Colon - Colon enterocytes, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Corticotropes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA021509 Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 77: Intestine - Digestion" "Cluster 15: Non-specific - Transcription" "Cluster 32: Non-specific - Cell proliferation" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" "Nucleoplasm, Cytosol" Vesicles "HPA021509: " "unprognostic (3.30e-2)" "unprognostic (3.64e-2)" "unprognostic (1.74e-1)" "unprognostic (1.01e-2)" "unprognostic (6.98e-2)" "unprognostic (3.81e-2)" "unprognostic (8.47e-3)" "potential prognostic favorable (4.27e-4)" "unprognostic (3.24e-2)" "potential prognostic favorable (2.93e-4)" "unprognostic (1.35e-1)" "potential prognostic favorable (5.73e-4)" "unprognostic (6.71e-2)" "unprognostic (1.86e-1)" "unprognostic (1.81e-1)" "unprognostic (3.46e-1)" "unprognostic (1.39e-1)" "potential prognostic unfavorable (4.18e-4)" "potential prognostic favorable (9.88e-4)" "unprognostic (3.74e-1)" "unprognostic (1.33e-1)" "unprognostic (8.37e-2)" ENTR1 "NY-CO-3, SDCCAG3" ENSG00000165689 "Endosome associated trafficking regulator 1" Q96C92 9 136401922-136410614 "Predicted intracellular proteins" "Cell cycle, Cell division, Cilium biogenesis/degradation, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 74.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029303 Approved NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 70: Non-specific - Protein processing" "Cluster 6: Non-specific - Immune response" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 17: Non-specific - RNA processing" 31 "HPA029303: " "unprognostic (5.80e-2)" "unprognostic (7.86e-3)" "unprognostic (8.32e-3)" "unprognostic (3.05e-1)" "unprognostic (1.55e-1)" "unprognostic (2.67e-1)" "potential prognostic favorable (1.11e-4)" "unprognostic (2.48e-2)" "unprognostic (3.77e-2)" "unprognostic (3.42e-3)" "unprognostic (7.04e-2)" "unprognostic (1.26e-1)" "potential prognostic unfavorable (6.49e-4)" "unprognostic (8.40e-2)" "unprognostic (8.58e-3)" "unprognostic (9.79e-2)" "unprognostic (1.85e-2)" "unprognostic (4.48e-2)" "unprognostic (1.47e-1)" "unprognostic (2.76e-1)" "unprognostic (6.04e-2)" "potential prognostic unfavorable (9.58e-4)" "unprognostic (7.64e-2)" "unprognostic (5.81e-2)" "unprognostic (6.94e-2)" "unprognostic (3.82e-2)" "unprognostic (1.49e-1)" "unprognostic (2.24e-3)" "unprognostic (1.33e-3)" ENTREP1 "C9orf61, ENTREP, FAM189A2, X123" ENSG00000135063 "Endosomal transmembrane epsin interactor 1" Q15884 9 69324567-69392558 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 45.9;thyroid gland: 50.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 189.5;Astrocytes: 490.6;Cardiomyocytes: 179.5;Gonadotrophs: 216.8;Müller glia: 198.5;Myonuclei: 354.0;Smooth muscle cells: 459.6;Thymic myoid cells: 257.0" "Cell type enriched" "Detected in many" 4 "astrocyte: 743.8" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 33.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Alveolar cells type 1, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029411, HPA057207" Approved NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 44: Non-specific - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 28: Astrocytes - Homeostasis & neuron support" 22 "HPA029411: , HPA057207: " "unprognostic (6.10e-2)" "unprognostic (3.86e-3)" "unprognostic (5.16e-2)" "unprognostic (1.03e-1)" "unprognostic (1.19e-1)" "unprognostic (3.00e-2)" "unprognostic (1.14e-1)" "potential prognostic favorable (3.20e-6)" "potential prognostic favorable (8.79e-4)" "potential prognostic favorable (1.39e-5)" "unprognostic (3.17e-2)" "unprognostic (9.98e-2)" "unprognostic (2.52e-2)" "unprognostic (4.41e-3)" "unprognostic (4.64e-3)" "unprognostic (2.43e-1)" "unprognostic (3.29e-3)" "unprognostic (6.60e-2)" "unprognostic (1.68e-2)" "unprognostic (4.21e-1)" "unprognostic (5.80e-2)" "unprognostic (1.63e-1)" ENTREP2 "FAM189A1, KIAA0574, TMEM228" ENSG00000104059 "Endosomal transmembrane epsin interactor 2" O60320 15 29120252-29570979 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 23.2" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 192.5;Brain inhibitory neurons: 150.1;Choroid plexus epithelial cells: 312.3;Distal convoluted tubule cells: 126.0;Oligodendrocyte progenitor cells: 92.5;Other brain neurons: 135.3;Papillary tip epithelial cells: 56.2;Proximal tubule cells: 163.4;Renal connecting tubule cells: 113.3" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in single" 6 "Kidney Renal Papillary Cell Carcinoma (TCGA): 3.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Bile duct cancer: 2.1" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009410, HPA010637" Uncertain Approved Nucleoplasm,Vesicles,Aggresome NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" Nucleoplasm "Vesicles, Aggresome" "HPA009410: , HPA010637: " "unprognostic (1.70e-1)" "unprognostic (1.77e-1)" "unprognostic (1.44e-1)" ENTREP3 "C1orf2, cote1, FAM189B" ENSG00000160767 "Endosomal transmembrane epsin interactor 3" P81408 1 155247205-155255483 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 9.8;Bergmann glia: 11.3;Brain excitatory neurons: 16.7;Brain inhibitory neurons: 14.9;Choroid plexus epithelial cells: 5.2;Distal convoluted tubule cells: 5.9;Ependymal cells: 5.4;Loop of henle epithelial cells: 6.2;Microglia: 4.8;Oligodendrocyte progenitor cells: 11.9;Oligodendrocytes: 9.4;Other brain neurons: 16.5;Papillary tip epithelial cells: 6.4;Podocytes: 5.2;Proximal tubule cells: 5.4;Renal collecting duct principal cells: 6.1;Renal connecting tubule cells: 4.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 2.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006659, HPA050674" Uncertain Supported Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 102: Non-specific - Mixed function" 2 Nucleoplasm "HPA006659: , HPA050674: " "unprognostic (2.10e-1)" "unprognostic (9.27e-2)" "unprognostic (7.15e-2)" "unprognostic (1.39e-3)" "unprognostic (4.40e-2)" "unprognostic (2.32e-2)" "unprognostic (8.60e-2)" "unprognostic (1.02e-2)" "unprognostic (7.37e-3)" "unprognostic (2.89e-2)" "potential prognostic favorable (7.28e-4)" "unprognostic (6.30e-2)" "unprognostic (8.32e-3)" "unprognostic (2.80e-3)" "potential prognostic unfavorable (9.49e-4)" "unprognostic (1.82e-3)" "unprognostic (3.55e-1)" "unprognostic (2.09e-1)" "unprognostic (2.01e-1)" "unprognostic (8.93e-2)" "unprognostic (1.11e-1)" "unprognostic (9.13e-2)" "unprognostic (1.83e-1)" "unprognostic (2.53e-2)" "unprognostic (4.16e-2)" "unprognostic (7.66e-2)" "unprognostic (4.89e-2)" "unprognostic (7.20e-2)" "unprognostic (1.31e-1)" "unprognostic (1.14e-3)" "unprognostic (2.62e-1)" ENY2 "DC6, FLJ20480, Sus1" ENSG00000120533 "ENY2 transcription and export complex 2 subunit" Q9NPA8 8 109334324-109345954 "Essential proteins, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Transcription, Transcription regulation, Translocation, Transport" "Activator, Chromatin regulator" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 690.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024648 Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 40: Non-specific - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 148 "Nucleoplasm, Mitochondria" "HPA024648: " "unprognostic (1.30e-2)" "potential prognostic unfavorable (9.02e-4)" "unprognostic (1.93e-1)" "unprognostic (2.93e-1)" "unprognostic (2.20e-1)" "unprognostic (1.11e-1)" "unprognostic (1.53e-2)" "unprognostic (5.25e-2)" "unprognostic (4.04e-3)" "unprognostic (5.02e-3)" "unprognostic (1.73e-1)" "unprognostic (1.72e-3)" "unprognostic (2.11e-3)" "unprognostic (4.96e-3)" "potential prognostic unfavorable (2.20e-4)" "potential prognostic unfavorable (1.03e-4)" "unprognostic (1.80e-2)" "unprognostic (2.21e-3)" "unprognostic (1.95e-1)" "unprognostic (1.39e-1)" "unprognostic (2.28e-2)" "unprognostic (2.23e-3)" "unprognostic (5.46e-3)" "unprognostic (5.90e-3)" "unprognostic (2.41e-1)" "unprognostic (3.26e-1)" "unprognostic (9.81e-2)" "unprognostic (6.41e-2)" "unprognostic (1.74e-1)" "unprognostic (8.94e-2)" "unprognostic (7.07e-2)" EOGT "AER61, C3orf64, FLJ33770" ENSG00000163378 "EGF domain specific O-linked N-acetylglucosamine transferase" Q5NDL2 3 68975217-69013684 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 141.1;Salivary myoepithelial cells: 99.8;Smooth muscle cells: 105.9;Vascular smooth muscle cells: 81.5" "Cell type enhanced" "Detected in all" "endothelial cell: 153.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019460 Approved Approved "Nucleoplasm,Nuclear membrane,Cytosol" "Intracellular and membrane" Enzyme NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 62: Smooth muscle cells - Muscle contraction" "Nucleoplasm, Nuclear membrane" Cytosol "HPA019460: " "unprognostic (2.39e-2)" "unprognostic (4.02e-1)" "unprognostic (7.67e-2)" "unprognostic (3.34e-1)" "unprognostic (1.65e-1)" "unprognostic (3.98e-2)" "unprognostic (6.50e-2)" "unprognostic (1.27e-1)" "unprognostic (2.96e-2)" "unprognostic (9.18e-2)" "unprognostic (2.83e-2)" "unprognostic (2.77e-2)" "potential prognostic unfavorable (5.46e-4)" "unprognostic (4.06e-2)" "unprognostic (9.32e-3)" "unprognostic (7.76e-2)" "unprognostic (6.54e-2)" "unprognostic (1.80e-1)" "unprognostic (3.57e-3)" "unprognostic (1.07e-1)" "unprognostic (8.74e-2)" "unprognostic (1.88e-1)" "unprognostic (2.33e-1)" "unprognostic (1.49e-2)" "unprognostic (5.00e-2)" "unprognostic (3.52e-1)" "unprognostic (9.88e-2)" "unprognostic (1.69e-2)" "unprognostic (4.52e-2)" EOLA1 "CXorf40, CXorf40A" ENSG00000197620 "Endothelium and lymphocyte associated ASCH domain 1" Q8TE69 X 149540355-149550510 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 103.2;Cytotrophoblasts: 34.1;Epicardial cells: 47.8;Syncytiotrophoblasts: 84.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells" "Low region specificity" "Detected in all" HPA060897 Approved NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 27: Breast cancer - Unknown function" "Cluster 103: Non-specific - Basic cellular processes" 1 "HPA060897: " "unprognostic (1.75e-2)" "unprognostic (8.06e-2)" "unprognostic (1.42e-2)" "unprognostic (1.66e-2)" "unprognostic (2.74e-1)" "validated prognostic unfavorable (8.96e-5)" "validated prognostic unfavorable (4.35e-5)" "unprognostic (1.41e-1)" "unprognostic (2.40e-1)" "unprognostic (2.11e-3)" "unprognostic (1.49e-1)" "unprognostic (5.55e-3)" "unprognostic (4.52e-2)" "unprognostic (2.17e-2)" "unprognostic (1.37e-1)" "unprognostic (5.55e-2)" "unprognostic (9.20e-2)" "unprognostic (5.31e-2)" "unprognostic (5.40e-2)" "unprognostic (2.84e-2)" "unprognostic (2.78e-1)" "unprognostic (8.95e-2)" "unprognostic (5.23e-2)" "unprognostic (1.53e-1)" "unprognostic (1.44e-1)" "unprognostic (4.65e-2)" "unprognostic (4.22e-1)" "unprognostic (7.31e-2)" "unprognostic (4.31e-2)" EOLA2 CXorf40B ENSG00000197021 "Endothelium and lymphocyte associated ASCH domain 2" Q96DE9 X 149929527-149938700 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 60.6;Granulosa cells: 43.0;Migrating cytotrophoblasts: 39.8;Oocytes: 50.7;Syncytiotrophoblasts: 104.4" "Cell type enhanced" "Detected in all" "vascular associated smooth muscle cell: 11.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells" HPA060897 Approved NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 55: Non-specific - Transcription" "Cluster 36: Non-specific - mRNA processing" "Cluster 103: Non-specific - Basic cellular processes" "HPA060897: " "unprognostic (1.89e-2)" "unprognostic (5.66e-2)" "unprognostic (6.54e-3)" "unprognostic (6.23e-2)" "unprognostic (2.29e-2)" "unprognostic (9.17e-3)" "unprognostic (1.95e-1)" "unprognostic (1.26e-1)" "unprognostic (1.12e-2)" "unprognostic (3.71e-3)" "unprognostic (3.21e-2)" "unprognostic (2.42e-1)" "potential prognostic unfavorable (1.02e-4)" "unprognostic (2.23e-1)" "unprognostic (1.44e-2)" "unprognostic (1.02e-1)" "unprognostic (9.74e-2)" "unprognostic (6.15e-2)" "unprognostic (1.67e-1)" "unprognostic (5.46e-2)" "unprognostic (5.84e-2)" "unprognostic (3.49e-2)" "unprognostic (1.46e-1)" "unprognostic (1.57e-2)" "unprognostic (1.46e-1)" "unprognostic (2.40e-1)" "unprognostic (1.04e-1)" "unprognostic (2.61e-3)" "unprognostic (2.16e-1)" EOMES TBR2 ENSG00000163508 Eomesodermin O95936 3 27715949-27722711 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Adaptive immunity, Differentiation, Gastrulation, Immunity, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 15.1;lymphoid tissue: 14.0" "Group enriched" "Detected in some" 6 "NK-cells: 67.7;T-cells: 37.2" "Group enriched" "Detected in some" 24 "leukocyte: 39.8;upper rhombic lip: 20.3" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 13.6" "Region enriched" "Detected in some" 14 "cerebellum: 17.1" "Group enriched" "Detected in many" 7 "gdT-cell: 16.6;MAIT T-cell: 26.2;memory CD8 T-cell: 19.4;naive CD8 T-cell: 11.9;NK-cell: 33.0" "Group enriched" "Detected in many" 107 "NK-cells: 33.0;T-cells: 26.2" "Group enriched" "Detected in some" 5 "lymphoma: 3.6;Rhabdoid: 8.5" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Minor Salivary Gland - T-cells, Testis - Spermatogonia, Thyroid gland - T-cells" "Region enriched" "Detected in many" 8 "olfactory bulb: 77.5" "Group enriched" "Detected in some" 23 "cerebellum: 42.5;olfactory bulb: 18.3" HPA028896 Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 35: Non-specific - DNA binding" "Cluster 50: Lymphoma - Unknown function" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" Nucleoplasm "Golgi apparatus, Cytosol" "HPA028896: " "unprognostic (1.56e-3)" "unprognostic (3.19e-2)" "unprognostic (1.77e-3)" "unprognostic (6.70e-2)" "unprognostic (1.35e-2)" "unprognostic (1.17e-1)" "potential prognostic favorable (4.54e-5)" "unprognostic (1.60e-2)" "unprognostic (2.92e-1)" "unprognostic (3.58e-3)" "unprognostic (1.42e-1)" "unprognostic (2.11e-1)" "unprognostic (9.28e-2)" "unprognostic (9.16e-2)" "unprognostic (2.49e-1)" EP300 "KAT3B, p300" ENSG00000100393 "E1A binding protein p300" Q09472 22 41092592-41180077 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Acyltransferase, Transferase" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 447.5;Neutrophils: 860.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000146, HPA003128, HPA004112" Supported Supported Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 16: Non-specific - Transcription" "Cluster 66: Non-specific - Mitochondria" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 438 Nucleoplasm "Centrosome, Cytosol" "CAB000146: , HPA003128: , HPA004112: " "unprognostic (7.02e-2)" "unprognostic (1.18e-1)" "unprognostic (9.89e-2)" "unprognostic (4.26e-2)" "unprognostic (2.04e-1)" "unprognostic (1.02e-3)" "unprognostic (1.76e-2)" "unprognostic (2.79e-1)" "unprognostic (1.92e-1)" "unprognostic (1.27e-1)" "validated prognostic favorable (1.07e-5)" "validated prognostic favorable (1.68e-5)" "unprognostic (1.22e-1)" "unprognostic (1.76e-2)" "unprognostic (3.30e-1)" "unprognostic (8.42e-2)" "unprognostic (1.01e-1)" "unprognostic (7.79e-3)" "unprognostic (1.30e-3)" "unprognostic (2.35e-2)" "unprognostic (7.28e-2)" "unprognostic (7.45e-2)" "unprognostic (1.30e-1)" "unprognostic (1.61e-1)" "unprognostic (5.65e-3)" "unprognostic (1.62e-2)" "unprognostic (1.87e-1)" "unprognostic (2.89e-1)" "unprognostic (2.88e-1)" "unprognostic (3.25e-2)" "unprognostic (2.50e-2)" EP400 "CAGH32, DKFZP434I225, KIAA1498, KIAA1818, P400, TNRC12" ENSG00000183495 "E1A binding protein p400" Q96L91 12 131949942-132080460 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 4.1;dendritic cells: 4.8;T-cells: 1.8" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016704, HPA049013" Supported Supported Nucleoplasm NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 11: Neuronal - Sensory perception" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 61 Nucleoplasm "HPA016704: , HPA049013: " "unprognostic (1.05e-1)" "unprognostic (2.90e-1)" "unprognostic (2.50e-1)" "unprognostic (3.51e-1)" "unprognostic (5.49e-2)" "unprognostic (2.15e-2)" "unprognostic (2.08e-1)" "unprognostic (3.38e-1)" "unprognostic (1.86e-1)" "unprognostic (3.23e-2)" "unprognostic (1.10e-2)" "unprognostic (2.61e-1)" "unprognostic (3.55e-1)" "potential prognostic unfavorable (1.14e-5)" "unprognostic (2.51e-1)" "unprognostic (9.68e-2)" "unprognostic (4.48e-1)" "unprognostic (1.11e-1)" "unprognostic (4.72e-3)" "unprognostic (7.15e-2)" "unprognostic (1.83e-1)" "unprognostic (1.51e-3)" "unprognostic (2.87e-3)" "unprognostic (2.07e-1)" "unprognostic (1.35e-1)" "unprognostic (2.12e-3)" "unprognostic (1.16e-1)" "unprognostic (2.52e-1)" "unprognostic (2.81e-1)" "unprognostic (1.74e-2)" "unprognostic (6.19e-2)" EPAS1 "bHLHe73, HIF2A, HLF, MOP2, PASD2" ENSG00000116016 "Endothelial PAS domain protein 1" Q99814 2 46293667-46386697 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Angiogenesis, Differentiation, Host-virus interaction, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Congenital erythrocytosis, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 388.8;placenta: 419.0" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 583.5;Extravillous trophoblasts: 1049.1;Pericytes: 619.2;Respiratory basal cells: 657.3;Respiratory secretory cells: 722.3;Syncytiotrophoblasts: 996.6;Vascular endothelial cells: 1356.1" "Group enriched" "Detected in all" 4 "endothelial cell: 1673.4;pericyte: 727.1;vascular associated smooth muscle cell: 610.1" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 231.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 18 "basophil: 20.7;eosinophil: 8.4" "Lineage enriched" "Detected in single" 26 "granulocytes: 20.7" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Pituitary gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031200, HPA069697" Supported "Nucleoplasm,Actin filaments,Cytokinetic bridge,Cytosol" Yes NA "Cluster 46: Basophils - Proteolysis" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 43 Nucleoplasm "Actin filaments, Cytokinetic bridge, Cytosol" "HPA031200: , HPA069697: " "unprognostic (1.14e-1)" "unprognostic (1.51e-1)" "unprognostic (1.55e-2)" "unprognostic (1.03e-2)" "unprognostic (1.42e-1)" "unprognostic (2.07e-2)" "unprognostic (9.03e-2)" "potential prognostic unfavorable (3.95e-4)" "unprognostic (9.01e-2)" "unprognostic (1.67e-1)" "validated prognostic favorable (5.01e-10)" "validated prognostic favorable (1.32e-4)" "unprognostic (7.43e-2)" "unprognostic (1.03e-1)" "unprognostic (3.50e-2)" "unprognostic (5.04e-2)" "unprognostic (7.29e-2)" "unprognostic (1.65e-1)" "unprognostic (3.21e-2)" "unprognostic (9.83e-2)" "unprognostic (8.80e-2)" "unprognostic (6.22e-2)" "unprognostic (8.41e-2)" "unprognostic (2.10e-1)" "unprognostic (5.28e-2)" "unprognostic (1.40e-1)" "unprognostic (6.29e-2)" "unprognostic (1.49e-2)" "unprognostic (1.12e-1)" "unprognostic (1.22e-2)" "unprognostic (1.42e-1)" EPB41 "4.1R, EL1" ENSG00000159023 "Erythrocyte membrane protein band 4.1" P11171 1 28887091-29120046 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell cycle, Cell division, Mitosis, Transport" "Actin-binding, Calmodulin-binding" "Elliptocytosis, Hereditary hemolytic anemia, Pyropoikilocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 74.1" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 900.5;Neutrophils: 878.8;Retinal bipolar cells: 769.2;Rod photoreceptor cells: 1120.2" "Cell type enhanced" "Detected in all" "upper rhombic lip: 737.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 92.6" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 8 "cerebellum: 142.2" "HPA028076, HPA028096, HPA028412, HPA028414" Supported Approved "Nuclear bodies,Plasma membrane,Cell Junctions,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes No 7000000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 15: Non-specific - Transcription" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 15 "Plasma membrane, Cell Junctions" "Nuclear bodies, Cytokinetic bridge, Mitotic spindle, Cytosol" "HPA028076: , HPA028096: , HPA028412: , HPA028414: " "unprognostic (1.43e-1)" "unprognostic (1.88e-1)" "unprognostic (2.96e-1)" "unprognostic (2.00e-2)" "unprognostic (3.88e-2)" "unprognostic (3.56e-2)" "unprognostic (6.99e-2)" "unprognostic (1.51e-3)" "unprognostic (4.16e-3)" "unprognostic (6.60e-2)" "potential prognostic favorable (1.69e-4)" "unprognostic (1.03e-1)" "unprognostic (2.88e-2)" "unprognostic (3.65e-3)" "unprognostic (5.89e-2)" "unprognostic (3.64e-2)" "unprognostic (2.47e-1)" "unprognostic (9.97e-2)" "unprognostic (7.19e-3)" "unprognostic (6.86e-3)" "unprognostic (7.20e-2)" "unprognostic (6.31e-2)" "unprognostic (2.79e-1)" "unprognostic (7.99e-2)" "unprognostic (1.38e-2)" "unprognostic (3.19e-2)" "unprognostic (1.97e-1)" "unprognostic (5.14e-2)" "unprognostic (1.80e-1)" "unprognostic (4.17e-2)" "unprognostic (2.77e-1)" EPB41L1 "4.1N, KIAA0338" ENSG00000088367 "Erythrocyte membrane protein band 4.1 like 1" Q9H4G0 20 36091504-36232799 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 432.7;Distal convoluted tubule cells: 287.7;Loop of henle epithelial cells: 288.0;Renal connecting tubule cells: 373.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 10 "plasmacytoid DC: 1.0" "Lineage enriched" "Detected in single" 10 "dendritic cells: 1.0" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054104, HPA056817" Enhanced Supported "Plasma membrane" NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 36: Brain & Liver - Signaling" "Cluster 1: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 19 "Plasma membrane" "HPA054104: , HPA056817: " "potential prognostic favorable (6.57e-5)" "unprognostic (1.36e-1)" "unprognostic (9.41e-2)" "unprognostic (1.49e-2)" "unprognostic (1.94e-2)" "unprognostic (3.52e-2)" "unprognostic (1.84e-2)" "unprognostic (1.63e-2)" "unprognostic (3.64e-1)" "unprognostic (1.70e-1)" "validated prognostic favorable (4.67e-10)" "validated prognostic favorable (3.24e-5)" "unprognostic (2.14e-2)" "unprognostic (5.27e-2)" "unprognostic (6.44e-2)" "unprognostic (4.63e-2)" "unprognostic (2.04e-1)" "unprognostic (1.25e-1)" "unprognostic (1.84e-3)" "unprognostic (6.19e-3)" "unprognostic (1.67e-1)" "potential prognostic unfavorable (8.33e-4)" "unprognostic (5.34e-2)" "unprognostic (3.05e-1)" "unprognostic (1.78e-1)" "unprognostic (1.65e-1)" "unprognostic (2.29e-3)" "unprognostic (1.62e-1)" "unprognostic (2.56e-1)" "unprognostic (2.65e-1)" "unprognostic (7.94e-2)" EPB41L2 "4.1-G, 4.1G" ENSG00000079819 "Erythrocyte membrane protein band 4.1 like 2" O43491 6 130839347-131063322 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Mitosis, Transport" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 327.6" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 726.6;Fibro-adipogenic progenitors: 693.7;Kupffer cells: 805.6;Microglia: 1812.6;Müller glia: 869.1;Oligodendrocytes: 594.1;Rod photoreceptor cells: 2298.8;Sertoli cells: 651.8" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 2248.2;committed oligodendrocyte precursor: 1661.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Colon - Enteric glia cells, Kidney - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005730, HPA006642" Supported Enhanced "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA 160000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 30: White matter - Myelination" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 46 "Plasma membrane" "Nucleoplasm, Cell Junctions" "HPA005730: , HPA006642: " "unprognostic (9.57e-3)" "unprognostic (7.85e-2)" "unprognostic (6.65e-2)" "unprognostic (1.60e-2)" "unprognostic (1.86e-2)" "potential prognostic favorable (2.67e-4)" "unprognostic (1.08e-1)" "unprognostic (4.76e-3)" "unprognostic (8.70e-2)" "unprognostic (1.44e-2)" "potential prognostic favorable (1.92e-6)" "unprognostic (1.59e-2)" "unprognostic (7.03e-2)" "unprognostic (1.01e-3)" "unprognostic (1.89e-2)" "unprognostic (1.07e-1)" "unprognostic (4.53e-3)" "unprognostic (1.59e-1)" "unprognostic (3.54e-1)" "unprognostic (1.72e-3)" "unprognostic (7.64e-2)" "unprognostic (1.65e-1)" "unprognostic (3.02e-2)" "unprognostic (1.66e-1)" "unprognostic (1.81e-2)" "unprognostic (1.42e-2)" "unprognostic (4.14e-1)" "unprognostic (5.39e-2)" "unprognostic (3.31e-1)" "unprognostic (1.22e-1)" "unprognostic (3.79e-1)" EPB41L3 "4.1B, DAL1, KIAA0987" ENSG00000082397 "Erythrocyte membrane protein band 4.1 like 3" Q9Y2J2 18 5392381-5630700 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis Actin-binding "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 461.6;Enterocytes: 471.9;Esophageal apical cells: 440.7;Kupffer cells: 452.0;Late spermatids: 459.7;Macrophages: 479.3;monocytes: 600.8;Proximal tubule cells: 557.9;Retinal amacrine cells: 527.1;Retinal ganglion cells: 591.0;Sertoli cells: 461.0;Syncytiotrophoblasts: 542.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 7.7;non-classical monocyte: 12.5" "Lineage enriched" "Detected in many" 5 "monocytes: 12.5" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Kidney - Proximal tubular cells, Spleen - Macrophages, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028605 Enhanced Supported "Plasma membrane,Cell Junctions,Primary cilium,Basal body" NA NA 380000 "Cluster 40: Monocytes - Innate immune response" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 59 "Plasma membrane, Cell Junctions" "Primary cilium, Basal body" "HPA028605: " "unprognostic (1.77e-1)" "unprognostic (1.37e-2)" "unprognostic (9.32e-2)" "unprognostic (2.51e-1)" "unprognostic (1.95e-1)" "unprognostic (5.93e-2)" "unprognostic (2.30e-1)" "unprognostic (5.00e-2)" "unprognostic (8.30e-3)" "unprognostic (4.56e-2)" "potential prognostic favorable (2.61e-5)" "unprognostic (4.08e-2)" "unprognostic (1.48e-2)" "unprognostic (1.00e-1)" "unprognostic (9.99e-2)" "unprognostic (1.83e-1)" "unprognostic (1.07e-1)" "unprognostic (1.65e-1)" "unprognostic (2.18e-3)" "unprognostic (1.95e-1)" "unprognostic (2.51e-2)" "unprognostic (7.71e-2)" "unprognostic (8.21e-2)" "unprognostic (2.88e-2)" "unprognostic (2.58e-1)" "unprognostic (1.62e-1)" "unprognostic (2.01e-3)" "unprognostic (2.05e-1)" "unprognostic (8.77e-3)" "unprognostic (7.64e-2)" EPB41L4A NBL4 ENSG00000129595 "Erythrocyte membrane protein band 4.1 like 4A" Q9HCS5 5 112142441-112419313 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 532.1;Pituitary stem cells: 474.5;Vascular endothelial cells: 416.6" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 432.7;endothelial cell: 628.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Skeletal muscle - Endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA036580 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 32: Basophils - Transcription" "Cluster 22: Epididymis - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 15: Kidney cancer - Membrane components" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 2 "Plasma membrane" Nucleoplasm "HPA036580: " "unprognostic (3.13e-3)" "unprognostic (1.17e-1)" "unprognostic (1.28e-1)" "unprognostic (1.51e-1)" "unprognostic (6.87e-2)" "unprognostic (3.89e-1)" "unprognostic (9.61e-2)" "unprognostic (1.92e-1)" "unprognostic (5.20e-3)" "unprognostic (5.31e-1)" "potential prognostic favorable (3.77e-7)" "unprognostic (6.42e-3)" "unprognostic (2.79e-3)" "unprognostic (9.10e-2)" "unprognostic (8.86e-2)" "unprognostic (2.72e-2)" "unprognostic (1.17e-2)" "unprognostic (1.43e-1)" "unprognostic (1.04e-1)" "unprognostic (6.24e-2)" "unprognostic (4.16e-2)" "unprognostic (1.73e-1)" "unprognostic (4.60e-1)" "potential prognostic unfavorable (3.10e-4)" "unprognostic (1.76e-1)" "unprognostic (1.13e-3)" "unprognostic (9.12e-2)" "unprognostic (4.59e-2)" "unprognostic (1.22e-2)" "unprognostic (2.57e-1)" "unprognostic (9.81e-2)" EPB41L4B "EHM2, LULU2" ENSG00000095203 "Erythrocyte membrane protein band 4.1 like 4B" Q9H329 9 109171974-109321059 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 83.1;pancreas: 140.8" "Cell type enhanced" "Detected in many" "Colonocytes: 178.6;Hepatocytes: 226.3;Pancreatic acinar cells: 448.4;Respiratory ciliated cells: 148.6;Retinal horizontal cells: 166.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Colon - Colon enterocytes, Heart muscle - Cardiomyocytes, Minor Salivary Gland - Minor salivary gland ductal cells, Prostate - Prostate glandular cells, Stomach - Chief cells, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042862 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 23: Choroid plexus - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 1 "Plasma membrane, Cytosol" "HPA042862: " "unprognostic (3.43e-1)" "potential prognostic unfavorable (6.88e-5)" "unprognostic (1.99e-2)" "unprognostic (1.86e-1)" "unprognostic (3.74e-2)" "unprognostic (1.07e-1)" "unprognostic (5.18e-2)" "unprognostic (1.65e-2)" "unprognostic (9.97e-2)" "unprognostic (1.21e-1)" "potential prognostic unfavorable (5.98e-6)" "unprognostic (1.04e-1)" "unprognostic (2.28e-1)" "unprognostic (9.00e-2)" "unprognostic (1.30e-1)" "unprognostic (1.07e-1)" "unprognostic (3.34e-2)" "unprognostic (1.33e-1)" "unprognostic (3.87e-2)" "unprognostic (2.63e-1)" "unprognostic (1.05e-2)" "unprognostic (1.67e-1)" "unprognostic (1.98e-2)" "unprognostic (1.09e-2)" "unprognostic (6.31e-3)" "unprognostic (1.88e-1)" "unprognostic (7.13e-2)" "unprognostic (7.24e-2)" EPB41L5 "BE37, FLJ12957, KIAA1548, LULU, LULU1, YMO1, YRT" ENSG00000115109 "Erythrocyte membrane protein band 4.1 like 5" Q9HCM4 2 120013077-120179119 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Podocytes: 1344.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Liver - Hepatocytes, Lung - Alveolar cells type 1, Minor Salivary Gland - Minor salivary glandular cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037563, HPA037564" Uncertain Enhanced "Plasma membrane" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 76: Non-specific - Metabolism" "Cluster 2: Neurons - Nucleosome" "Cluster 15: Kidney cancer - Membrane components" "Cluster 57: Podocytes - Glomerular filtration" 22 "Plasma membrane" "HPA037563: , HPA037564: " "unprognostic (1.83e-2)" "unprognostic (7.96e-3)" "unprognostic (2.26e-1)" "unprognostic (7.22e-2)" "unprognostic (2.81e-2)" "unprognostic (2.01e-1)" "unprognostic (7.77e-2)" "unprognostic (6.11e-3)" "unprognostic (1.62e-2)" "unprognostic (7.37e-2)" "potential prognostic favorable (1.82e-10)" "unprognostic (3.32e-3)" "unprognostic (2.16e-2)" "unprognostic (2.87e-1)" "unprognostic (9.15e-2)" "potential prognostic favorable (6.54e-4)" "unprognostic (4.60e-2)" "unprognostic (4.09e-1)" "unprognostic (7.65e-3)" "unprognostic (2.74e-1)" "unprognostic (7.77e-2)" "unprognostic (1.04e-1)" "unprognostic (7.74e-2)" "unprognostic (7.37e-2)" "unprognostic (1.50e-2)" "unprognostic (6.00e-2)" "unprognostic (4.79e-2)" "unprognostic (8.29e-2)" "unprognostic (5.07e-1)" "unprognostic (2.22e-2)" "unprognostic (2.00e-1)" EPB42 "MGC116735, MGC116737, PA" ENSG00000166947 "Erythrocyte membrane protein band 4.2" P16452 15 43197227-43221018 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell shape, Erythrocyte maturation" "Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 31 "bone marrow: 93.3" "Group enriched" "Detected in some" 12 "Erythrocyte progenitors: 141.8;Erythrocytes: 82.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 84 "Leukemia: 8.3" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Erythroid cells, Pituitary gland - Neutrophils, Spleen - Erythrocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA040261 Supported Uncertain Nucleoplasm,Cytosol NA NA 840000 "Cluster 15: Bone marrow - Innate immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 4 "Nucleoplasm, Cytosol" "HPA040261: " EPC1 Epl1 ENSG00000120616 "Enhancer of polycomb homolog 1" Q9H2F5 10 32267751-32378798 "Predicted intracellular proteins" "Differentiation, Growth regulation, Spermatogenesis, Transcription, Transcription regulation" "Activator, Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "bone marrow: 141.2" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005811, HPA071652" Supported "Nucleoplasm,Nucleoli,Nuclear bodies" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 25: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 9: T-cells - Adaptive immunity: Regulation" 34 Nucleoplasm "Nucleoli, Nuclear bodies" "HPA005811: , HPA071652: " "unprognostic (4.16e-3)" "unprognostic (3.94e-2)" "unprognostic (2.83e-1)" "unprognostic (2.63e-1)" "unprognostic (1.91e-2)" "unprognostic (6.14e-2)" "unprognostic (1.48e-1)" "potential prognostic favorable (3.25e-5)" "potential prognostic favorable (3.44e-4)" "unprognostic (2.60e-2)" "validated prognostic favorable (3.87e-5)" "validated prognostic favorable (2.98e-4)" "unprognostic (5.97e-2)" "unprognostic (2.47e-3)" "unprognostic (6.54e-3)" "unprognostic (1.45e-2)" "unprognostic (2.89e-1)" "unprognostic (2.45e-1)" "unprognostic (2.54e-1)" "unprognostic (1.07e-1)" "unprognostic (1.25e-1)" "unprognostic (2.74e-2)" "unprognostic (6.47e-3)" "unprognostic (4.42e-1)" "unprognostic (4.07e-1)" "unprognostic (3.13e-2)" "unprognostic (2.95e-3)" "unprognostic (1.31e-1)" "unprognostic (1.09e-1)" "unprognostic (6.87e-2)" "unprognostic (3.04e-1)" EPC2 DKFZP566F2124 ENSG00000135999 "Enhancer of polycomb homolog 2" Q52LR7 2 148644440-148787569 "Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036759 Uncertain Approved "Nuclear speckles" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 7: Non-specific - Transcription" 39 "Nuclear speckles" "HPA036759: " "unprognostic (1.56e-2)" "unprognostic (5.65e-2)" "unprognostic (1.78e-1)" "unprognostic (2.29e-2)" "unprognostic (4.48e-2)" "unprognostic (1.50e-1)" "unprognostic (3.49e-2)" "unprognostic (1.07e-2)" "unprognostic (5.69e-2)" "unprognostic (6.35e-3)" "validated prognostic favorable (2.09e-5)" "validated prognostic favorable (4.55e-4)" "unprognostic (3.66e-3)" "unprognostic (1.45e-3)" "unprognostic (7.00e-2)" "unprognostic (1.93e-2)" "unprognostic (1.33e-1)" "unprognostic (1.30e-1)" "unprognostic (4.91e-2)" "unprognostic (1.21e-1)" "unprognostic (6.52e-2)" "unprognostic (2.28e-1)" "unprognostic (1.48e-2)" "unprognostic (1.92e-1)" "unprognostic (1.33e-2)" "unprognostic (1.98e-1)" "unprognostic (1.44e-1)" "unprognostic (8.84e-3)" "unprognostic (2.08e-1)" "unprognostic (1.37e-1)" "unprognostic (1.53e-1)" EPCAM "17-1A, 323/A3, Ber-Ep4, BerEp4, CD326, CO-17A, EGP-2, EGP34, EGP40, Ep-CAM, ESA, GA733-2, HEA125, KS1/4, KSA, Ly74, M4S1, MH99, MIC18, MK-1, MOC-31, MOC31, TACST-1, TACSTD1, TROP1" ENSG00000119888 "Epithelial cell adhesion molecule" P16422 2 47345158-47387601 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Tumor antigen" "Cancer-related genes, Disease variant, FDA approved drug targets, Hereditary nonpolyposis colorectal cancer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 756.2" "Cell type enhanced" "Detected in many" "Colonocytes: 2714.8;Enteric stem cells: 1605.1;Enteric transient amplifying cells: 1859.2;Enterocytes: 2694.4;Goblet cells: 1377.2;Oocytes: 819.7;Pancreatic duct cells: 803.5;Paneth cells: 1256.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 762.9" "Breast - Breast glandular cells, Colon - Colon enterocytes, Liver - Cholangiocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Skin - Eccrine sweat gland cells, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB003809, HPA026761, CAB030012, CAB055098, HPA067463" Enhanced Supported "Plasma membrane" NA NA 8800 "Cluster 77: Intestine - Digestion" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 7 "Plasma membrane" "CAB003809: , CAB030012: , CAB055098: , HPA026761: , HPA067463: " "unprognostic (3.41e-2)" "unprognostic (1.52e-2)" "unprognostic (8.29e-3)" "unprognostic (2.22e-1)" "unprognostic (4.13e-1)" "unprognostic (8.83e-3)" "unprognostic (9.22e-3)" "unprognostic (4.51e-2)" "unprognostic (2.73e-1)" "potential prognostic favorable (3.91e-4)" "unprognostic (4.55e-2)" "unprognostic (3.08e-2)" "unprognostic (1.83e-1)" "unprognostic (5.00e-2)" "unprognostic (9.92e-2)" "unprognostic (2.74e-2)" "unprognostic (5.14e-2)" "unprognostic (4.88e-3)" "unprognostic (2.48e-2)" "unprognostic (2.18e-1)" "unprognostic (3.62e-2)" "unprognostic (1.84e-1)" "unprognostic (2.81e-2)" "unprognostic (3.65e-1)" "unprognostic (1.42e-2)" "unprognostic (6.94e-3)" "unprognostic (7.93e-2)" "unprognostic (3.56e-2)" "unprognostic (6.07e-2)" EPDR1 "EPDR, MERP-1, MERP1, UCC1" ENSG00000086289 "Ependymin related 1" Q9UM22 7 37920640-37951936 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 113.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 59.9;Alveolar cells type 2: 80.0;Brain excitatory neurons: 68.9;Decidual stromal cells: 55.9;Epididymal clear cells: 106.1;Epididymal efferent duct ciliated cells: 63.8;Granulosa cells: 54.3;Other brain neurons: 91.6;Peritubular myoid cells: 83.6" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 111.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 2.2" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in all" "Kidney cancer: 143.0" "Adrenal gland - Adrenal cortex cells, Skeletal muscle - Skeletal myocytes, Spleen - Fibroblasts_1, Spleen - Fibroblasts_2, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026298, HPA072321" Enhanced "Secreted in other tissues" "No annotated function" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 24: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 98: Neurons - Neurotransmission & signaling" 34 "CAB026298: , HPA072321: " "unprognostic (1.84e-2)" "unprognostic (8.82e-3)" "unprognostic (3.06e-1)" "unprognostic (1.21e-1)" "unprognostic (1.19e-1)" "unprognostic (1.59e-1)" "unprognostic (1.36e-1)" "unprognostic (1.25e-3)" "unprognostic (1.90e-2)" "unprognostic (2.82e-1)" "unprognostic (2.10e-3)" "unprognostic (8.78e-2)" "unprognostic (3.01e-2)" "unprognostic (1.56e-3)" "potential prognostic unfavorable (8.61e-5)" "unprognostic (1.07e-1)" "unprognostic (2.79e-2)" "unprognostic (1.16e-3)" "unprognostic (1.33e-1)" "unprognostic (2.79e-1)" "unprognostic (1.40e-1)" "unprognostic (1.86e-1)" "unprognostic (1.11e-3)" "unprognostic (1.60e-1)" "unprognostic (3.52e-2)" "unprognostic (2.67e-1)" "unprognostic (9.12e-2)" "potential prognostic unfavorable (7.98e-5)" "unprognostic (1.06e-1)" "unprognostic (8.07e-3)" "unprognostic (1.83e-1)" EPG5 "hEPG5, KIAA1632" ENSG00000152223 "Ectopic P-granules 5 autophagy tethering factor" Q9HCE0 18 45800581-45967329 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Autophagy "Cataract, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 288.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031689 Uncertain Approved "Nuclear speckles" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 1 "Nuclear speckles" "HPA031689: " "unprognostic (4.93e-2)" "unprognostic (4.95e-2)" "unprognostic (4.18e-2)" "unprognostic (6.39e-2)" "unprognostic (5.52e-2)" "unprognostic (1.02e-1)" "unprognostic (3.03e-2)" "unprognostic (9.45e-2)" "unprognostic (2.16e-1)" "unprognostic (4.55e-3)" "unprognostic (2.52e-3)" "unprognostic (1.21e-3)" "unprognostic (7.65e-3)" "unprognostic (1.05e-1)" "unprognostic (3.67e-2)" "unprognostic (6.01e-2)" "unprognostic (2.66e-1)" "unprognostic (7.71e-2)" "unprognostic (9.37e-2)" "unprognostic (6.35e-2)" "unprognostic (2.02e-3)" "unprognostic (1.39e-2)" "unprognostic (4.16e-2)" "unprognostic (2.63e-1)" "unprognostic (4.94e-2)" "unprognostic (1.99e-1)" "unprognostic (8.16e-2)" "unprognostic (1.08e-1)" "unprognostic (2.56e-1)" "unprognostic (9.91e-2)" EPGN "ALGV3072, EPG, PRO9904" ENSG00000182585 "Epithelial mitogen" Q6UW88 4 74308470-74316789 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "esophagus: 46.0" "Cell type enhanced" "Detected in some" "Esophageal apical cells: 305.8;Esophageal suprabasal cells: 105.8;Hematopoietic stem cells: 134.4;Innate lymphoid cells: 51.2;Megakaryocyte progenitors: 25.9;Megakaryocyte-Erythroid progenitors: 86.5;Ocular epithelial cells: 30.9;Suprabasal keratinocytes: 25.8" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Head and Neck Squamous Cell Carcinoma (TCGA): 21.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA014420 Approved Nucleoplasm,Vesicles,Cytosol "Secreted in other tissues" "Growth factor" NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 48: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 85: Squamous epithelial cells - Keratinization" 1 "Nucleoplasm, Cytosol" Vesicles "HPA014420: " "potential prognostic unfavorable (7.55e-4)" "unprognostic (2.12e-1)" "unprognostic (1.48e-2)" "unprognostic (2.68e-1)" "unprognostic (3.15e-1)" "unprognostic (4.91e-2)" "unprognostic (3.40e-2)" "unprognostic (4.01e-1)" "unprognostic (6.51e-2)" "unprognostic (8.77e-2)" EPHA1 "EPH, EPHT, EPHT1" ENSG00000146904 "EPH receptor A1" P21709 7 143390289-143408856 "Cancer-related genes, Enzymes, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Cell adhesion" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 55.7;parathyroid gland: 194.2" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 2.6;Choroid plexus epithelial cells: 3.3;Distal convoluted tubule cells: 2.7;Early spermatids: 4.7;Esophageal apical cells: 2.5;Loop of henle epithelial cells: 5.0;Papillary tip epithelial cells: 9.3;Proximal tubule cells: 3.6;Renal collecting duct intercalated cells: 2.8;Renal collecting duct principal cells: 5.0;Renal connecting tubule cells: 3.5" "Cell type enhanced" "Detected in some" "leukocyte: 7.9" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "choroid plexus: 2.6" "Group enriched" "Detected in some" 6 "memory CD4 T-cell: 1.9;naive CD4 T-cell: 3.8;naive CD8 T-cell: 2.9" "Lineage enriched" "Detected in single" 8 "T-cells: 3.8" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Prostate - Prostate basal glandular cells, Testis - Late spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" CAB026144 Uncertain NA NA 5700000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 5: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 20 "CAB026144: " "unprognostic (1.87e-1)" "unprognostic (9.06e-2)" "unprognostic (5.91e-2)" "unprognostic (5.97e-2)" "unprognostic (2.14e-1)" "unprognostic (1.49e-2)" "unprognostic (2.06e-1)" "unprognostic (1.40e-2)" "potential prognostic favorable (8.11e-5)" "unprognostic (9.23e-2)" "potential prognostic favorable (6.44e-4)" "unprognostic (1.48e-2)" "unprognostic (9.04e-2)" "unprognostic (3.05e-1)" "unprognostic (7.26e-2)" "unprognostic (6.65e-2)" "unprognostic (6.30e-2)" "unprognostic (8.83e-2)" "unprognostic (1.76e-1)" "unprognostic (8.45e-3)" "unprognostic (2.01e-1)" "unprognostic (1.96e-1)" "unprognostic (8.24e-3)" "unprognostic (7.88e-2)" "unprognostic (1.53e-1)" "unprognostic (4.71e-2)" EPHA10 "FLJ16103, FLJ33655" ENSG00000183317 "EPH receptor A10" Q5JZY3 1 37713880-37765133 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.9;intestine: 12.5;testis: 12.4" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 50.5;Colonocytes: 33.1;Cone photoreceptor cells: 126.3;Early spermatids: 63.2;Gonadotrophs: 37.6;Late primary spermatocytes: 65.4;Late spermatids: 327.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Prostate - Prostate glandular cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027497 Uncertain "Intracellular and membrane" Receptor NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 33: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 6 "HPA027497: " "unprognostic (4.09e-2)" "unprognostic (1.04e-1)" "unprognostic (1.15e-3)" "unprognostic (1.62e-2)" "unprognostic (4.68e-2)" "unprognostic (3.05e-2)" "unprognostic (9.48e-3)" "unprognostic (2.10e-1)" "unprognostic (2.35e-1)" "unprognostic (1.32e-2)" "unprognostic (1.89e-1)" "unprognostic (2.92e-1)" "unprognostic (1.28e-3)" "unprognostic (1.33e-2)" "unprognostic (1.66e-2)" "unprognostic (4.58e-2)" "unprognostic (3.13e-1)" EPHA2 ECK ENSG00000142627 "EPH receptor A2" P29317 1 16124337-16156069 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, RAS pathway related proteins" "Angiogenesis, Apoptosis, Cell adhesion, Differentiation, Host-virus interaction" "Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Cataract, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 142.7" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 197.8;Endometrial luminal cells: 221.0;Esophageal apical cells: 1038.5;Esophageal suprabasal cells: 325.0;Ocular epithelial cells: 384.2;Prostatic hillock cells: 217.5;Respiratory basal cells: 192.0;Suprabasal keratinocytes: 251.0;Urothelial cells: 391.6" "Group enriched" "Detected in some" 4 "endothelial cell: 18.5;pericyte: 45.1;vascular associated smooth muscle cell: 30.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 94 "plasmacytoid DC: 9.4" "Lineage enriched" "Detected in single" 94 "dendritic cells: 9.4" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Colon - Endothelial cells, Minor Salivary Gland - Minor salivary gland basal cells, Pituitary gland - Endothelial cells, Prostate - Urothelial cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" CAB010464 Supported "Nuclear speckles,Golgi apparatus,Plasma membrane,Cell Junctions" NA Yes "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 128 "Plasma membrane, Cell Junctions" "Nuclear speckles, Golgi apparatus" "CAB010464: " "unprognostic (1.53e-2)" "unprognostic (7.88e-2)" "unprognostic (2.56e-1)" "unprognostic (5.74e-2)" "unprognostic (4.10e-1)" "unprognostic (1.92e-1)" "unprognostic (4.20e-2)" "unprognostic (1.30e-3)" "unprognostic (7.53e-2)" "unprognostic (1.91e-1)" "validated prognostic favorable (3.23e-5)" "validated prognostic favorable (6.42e-5)" "unprognostic (5.34e-2)" "unprognostic (4.66e-2)" "unprognostic (3.51e-2)" "unprognostic (3.45e-2)" "unprognostic (2.64e-1)" "unprognostic (2.90e-2)" "unprognostic (1.46e-1)" "unprognostic (6.79e-3)" "unprognostic (1.76e-1)" "potential prognostic unfavorable (1.75e-4)" "unprognostic (6.78e-2)" "unprognostic (2.73e-1)" "unprognostic (1.99e-1)" "unprognostic (1.46e-2)" "unprognostic (9.96e-3)" "unprognostic (1.27e-1)" "unprognostic (1.31e-1)" "unprognostic (1.95e-2)" "unprognostic (2.45e-1)" EPHA3 "ETK, ETK1, HEK, HEK4, TYRO4" ENSG00000044524 "EPH receptor A3" P29320 3 89107621-89482134 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 29.5" "Cell type enhanced" "Detected in many" "Adipocytes: 82.8;Brain inhibitory neurons: 112.0;Corticotrophs: 300.2;Fibro-adipogenic progenitors: 210.2;Fibroblasts: 90.1;Hepatic stellate cells: 77.5;Other brain neurons: 80.8;Pericytes: 165.9;Retinal bipolar cells: 132.1;Retinal ganglion cells: 81.1;Retinal horizontal cells: 360.6;Rod photoreceptor cells: 296.6;Somatotrophs: 96.9;Vascular smooth muscle cells: 133.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 12.8" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblasts_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010462, HPA069390" Approved Supported "Nucleoplasm,Nuclear membrane,Plasma membrane,Actin filaments,Cytosol" "Intracellular and membrane" Receptor NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 24: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 17 "Nuclear membrane, Plasma membrane, Cytosol" "Nucleoplasm, Actin filaments" "CAB010462: , HPA069390: " "unprognostic (3.91e-3)" "unprognostic (3.10e-3)" "unprognostic (2.82e-1)" "unprognostic (5.48e-2)" "unprognostic (1.80e-1)" "unprognostic (2.61e-1)" "unprognostic (1.98e-2)" "unprognostic (4.14e-3)" "unprognostic (1.14e-2)" "unprognostic (7.47e-2)" "unprognostic (6.37e-3)" "potential prognostic unfavorable (4.79e-6)" "unprognostic (2.15e-1)" "unprognostic (2.23e-2)" "unprognostic (7.61e-3)" "unprognostic (1.21e-1)" "unprognostic (4.25e-2)" "unprognostic (6.80e-3)" "unprognostic (2.09e-1)" "unprognostic (6.53e-2)" "unprognostic (1.51e-1)" "unprognostic (3.21e-1)" "unprognostic (2.17e-2)" "unprognostic (1.67e-2)" "unprognostic (2.39e-2)" "unprognostic (2.55e-2)" "unprognostic (5.56e-2)" EPHA4 "Hek8, TYRO1" ENSG00000116106 "EPH receptor A4" P54764 2 221418027-221574202 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.6" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 269.7;Choroid plexus epithelial cells: 872.0;Pituicytes/FSCs: 256.4;Sertoli cells: 555.7;Vascular endothelial cells: 230.1" "Cell type enhanced" "Detected in all" "hippocampal CA4: 1112.5" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 20.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "basophil: 1.6;gdT-cell: 1.7;MAIT T-cell: 1.7;memory B-cell: 1.3;memory CD4 T-cell: 2.5;memory CD8 T-cell: 1.7;naive B-cell: 1.2;naive CD4 T-cell: 1.0;NK-cell: 3.5;T-reg: 1.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB028368 Enhanced NA NA 8600000 "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 23: Choroid plexus - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 30 "CAB028368: " "unprognostic (3.95e-2)" "unprognostic (8.84e-2)" "unprognostic (2.18e-1)" "unprognostic (1.14e-3)" "unprognostic (9.93e-2)" "unprognostic (1.92e-1)" "unprognostic (7.89e-2)" "unprognostic (1.09e-2)" "unprognostic (2.98e-2)" "unprognostic (5.62e-2)" "potential prognostic favorable (7.56e-9)" "unprognostic (1.89e-3)" "unprognostic (1.28e-1)" "unprognostic (1.30e-2)" "unprognostic (1.02e-1)" "unprognostic (8.94e-3)" "unprognostic (4.93e-2)" "unprognostic (5.97e-2)" "unprognostic (1.01e-3)" "unprognostic (8.83e-2)" "unprognostic (6.35e-2)" "unprognostic (2.22e-1)" "unprognostic (3.10e-3)" "unprognostic (1.02e-1)" "unprognostic (9.04e-2)" "unprognostic (2.22e-1)" "unprognostic (2.85e-2)" "unprognostic (1.76e-1)" "unprognostic (4.13e-1)" "unprognostic (5.47e-2)" EPHA5 "CEK7, EHK1, Hek7, TYRO4" ENSG00000145242 "EPH receptor A5" P54756 4 65319563-65670495 "Enzymes, Predicted membrane proteins" Neurogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 10.5" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 106.4;Brain excitatory neurons: 296.3;Brain inhibitory neurons: 137.5;Lactotrophs: 275.0;Melanocytes: 120.9;Oligodendrocyte progenitor cells: 111.6;Other brain neurons: 205.9;Prostatic glandular cells: 290.2;Retinal amacrine cells: 100.2;Retinal ganglion cells: 258.8;Somatotrophs: 134.1" "Cell type enhanced" "Detected in all" "hippocampal CA4: 930.6" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 1.7;Prostate Adenocarcinoma (TCGA): 1.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 10.7;Sarcoma: 21.2" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Stomach - Chief cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034528 Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA 98000 "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" 13 "Golgi apparatus" "Vesicles, Plasma membrane" "HPA034528: " "unprognostic (4.73e-3)" "unprognostic (3.34e-1)" "unprognostic (1.44e-1)" EPHA6 FLJ35246 ENSG00000080224 "EPH receptor A6" Q9UF33 3 96814581-97761532 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "ovary: 3.8;testis: 7.7" "Group enriched" "Detected in many" 4 "Astrocytes: 312.0;Brain excitatory neurons: 909.0;Brain inhibitory neurons: 983.4;Early spermatids: 481.9;Gonadotrophs: 309.6;Late primary spermatocytes: 392.9;Late spermatids: 463.7;Other brain neurons: 709.8;Retinal amacrine cells: 382.3;Retinal ganglion cells: 668.3" "Cell type enhanced" "Detected in all" "eccentric medium spiny neuron: 3566.6" "Cancer enhanced" "Detected in some" "Prostate Adenocarcinoma (TCGA): 2.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 11.1;prostate cancer: 7.6;Rhabdoid: 7.2" "Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007397 Uncertain Approved "Mid piece" NA NA 36000 "Cluster 75: Ovary - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 35: Neurons - Synaptic function & neurogenesis" 10 "Mid piece" "HPA007397: " "unprognostic (1.19e-1)" "unprognostic (2.77e-2)" "unprognostic (1.51e-1)" "unprognostic (2.91e-3)" "unprognostic (1.69e-1)" "unprognostic (1.01e-1)" "unprognostic (3.69e-1)" "unprognostic (1.18e-1)" "unprognostic (9.47e-2)" EPHA7 Hek11 ENSG00000135333 "EPH receptor A7" Q15375 6 93240020-93419687 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "parathyroid gland: 65.8" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 274.0;Brain inhibitory neurons: 238.5;Breast lactating cells: 82.9;Epididymal efferent duct absorptive cells: 231.9;Epididymal efferent duct ciliated cells: 86.5;Fibro-adipogenic progenitors: 103.4;Lacrimal acinar cells: 226.5;Other brain neurons: 118.5;Podocytes: 85.4;Proximal tubule cells: 201.7;Retinal bipolar cells: 114.7;Smooth muscle cells: 88.6;Thyrotrophs: 226.4" "Cell type enhanced" "Detected in all" "hippocampal dentate gyrus: 902.2" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 8.1;Kidney Renal Papillary Cell Carcinoma (TCGA): 9.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 33.5;Sarcoma: 26.4" "Heart muscle - Cardiomyocytes, Pituitary gland - Thyrotropes, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Eccrine sweat gland cells, Spleen - Endothelial cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "hippocampal formation: 81.6" "HPA000858, CAB010496" Approved Approved "Principal piece" "Intracellular and membrane" Receptor NA NA 930000 "Cluster 69: Parathyroid gland - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" 33 "Principal piece" "CAB010496: , HPA000858: " "unprognostic (3.98e-1)" "unprognostic (1.87e-2)" "potential prognostic favorable (8.69e-5)" "unprognostic (9.03e-2)" "unprognostic (1.37e-1)" "unprognostic (1.04e-2)" "unprognostic (1.73e-3)" "unprognostic (1.19e-1)" "unprognostic (1.00e-1)" "unprognostic (3.57e-2)" "unprognostic (1.38e-2)" "unprognostic (6.79e-2)" "unprognostic (2.60e-1)" EPHA8 "EEK, Hek3" ENSG00000070886 "EPH receptor A8" P29322 1 22563489-22603595 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "choroid plexus: 31.5" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 31.9;Brain excitatory neurons: 4.7;Brain inhibitory neurons: 8.5;Choroid plexus epithelial cells: 11.7;Late primary spermatocytes: 4.3;Late spermatids: 18.7;Oocytes: 9.2;Other brain neurons: 4.5;Pancreatic islet cells: 4.3;Retinal amacrine cells: 5.0;Retinal horizontal cells: 12.0;Rod photoreceptor cells: 6.8" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 31.1;mammillary body: 38.8;midbrain-derived inhibitory: 31.1" "Cancer enhanced" "Detected in single" "Testicular Germ Cell Tumor (TCGA): 1.4" "Region enriched" "Detected in all" 5 "choroid plexus: 62.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Uterine cancer: 4.0" "Adrenal gland - Adrenal medulla cells" "Region enhanced" "Detected in many" "cerebellum: 13.0" "Region enriched" "Detected in many" 5 "cerebellum: 17.6" "CAB009660, HPA031433" Uncertain "Intracellular and membrane" Receptor NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 1: Neuronal - Visual perception" "Cluster 109: Neurons - Neuronal signaling" 19 "CAB009660: , HPA031433: " "unprognostic (7.51e-2)" "unprognostic (1.87e-1)" EPHB1 "EPHT2, Hek6" ENSG00000154928 "EPH receptor B1" P54762 3 134795260-135260467 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Neurogenesis" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.3" "Cell type enhanced" "Detected in many" "Astrocytes: 293.8;Brain excitatory neurons: 238.6;Brain inhibitory neurons: 209.1;Lactotrophs: 92.2;Oligodendrocyte progenitor cells: 151.8;Oligodendrocytes: 222.0;Other brain neurons: 121.0;pDCs: 235.3;Retinal ganglion cells: 96.6;Sertoli cells: 209.6;Thymic myoid cells: 247.5" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 823.0" "Cancer enriched" "Detected in many" 6 "Glioblastoma Multiforme (TCGA): 18.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 23 "neutrophil: 10.1;plasmacytoid DC: 23.3" "Group enriched" "Detected in many" 23 "dendritic cells: 23.3;granulocytes: 10.1" "Cancer enhanced" "Detected in many" "lymphoma: 10.5" "Breast - Breast myoepithelial cells, Kidney - Fibroblasts, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067740 Enhanced Supported "Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 27: Cerebellum - Synaptic function" "Cluster 2: Neurons - Nucleosome" "Cluster 50: Lymphoma - Unknown function" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 10 "Endoplasmic reticulum, Plasma membrane" Cytosol "HPA067740: " "unprognostic (1.66e-1)" "unprognostic (3.12e-1)" "unprognostic (2.54e-2)" "unprognostic (3.70e-1)" "unprognostic (1.46e-1)" "unprognostic (6.53e-2)" "unprognostic (1.49e-3)" "unprognostic (2.89e-1)" "unprognostic (2.52e-1)" "unprognostic (5.84e-2)" "unprognostic (1.27e-1)" "unprognostic (8.00e-2)" "unprognostic (1.50e-1)" "unprognostic (1.05e-1)" "unprognostic (6.67e-3)" "unprognostic (8.32e-2)" "unprognostic (9.50e-2)" "unprognostic (6.14e-2)" "unprognostic (1.25e-1)" "unprognostic (2.36e-1)" "unprognostic (5.80e-3)" "unprognostic (1.80e-1)" "unprognostic (8.12e-2)" "unprognostic (7.85e-2)" "unprognostic (1.77e-3)" "unprognostic (5.17e-2)" EPHB2 "DRT, EPHT3, ERK, Hek5, Tyro5" ENSG00000133216 "EPH receptor B2" P29323 1 22710839-22921500 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Neurogenesis "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 21.9" "Cell type enhanced" "Detected in many" "Enteric stem cells: 337.1;Enteric transient amplifying cells: 209.9;Late spermatids: 366.1;Neuroendocrine cells: 100.4;Paneth cells: 425.4;Pituicytes/FSCs: 100.3;Retinal amacrine cells: 117.1" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Colon Adenocarcinoma (TCGA): 74.6;Rectum Adenocarcinoma (TCGA): 72.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Skin - Outer root sheath cells, Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB013647, HPA071200" Approved Supported "Nucleoplasm,Plasma membrane" "Intracellular and membrane" Receptor No No 520000 "Cluster 77: Intestine - Digestion" "Cluster 30: White matter - Myelination" "Cluster 72: Neuronal - Signal transduction" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 25 "Plasma membrane" Nucleoplasm "CAB013647: , HPA071200: " "unprognostic (8.42e-2)" "unprognostic (1.03e-2)" "unprognostic (8.41e-2)" "unprognostic (6.28e-3)" "unprognostic (1.64e-3)" "unprognostic (6.59e-3)" "unprognostic (9.17e-2)" "unprognostic (6.57e-2)" "unprognostic (4.09e-2)" "unprognostic (1.04e-2)" "unprognostic (2.24e-2)" "unprognostic (9.05e-3)" "unprognostic (6.22e-3)" "unprognostic (1.39e-1)" "unprognostic (6.17e-2)" "potential prognostic unfavorable (3.18e-4)" "unprognostic (6.93e-3)" "unprognostic (5.85e-3)" "unprognostic (6.96e-3)" "unprognostic (3.58e-3)" "unprognostic (2.53e-2)" "unprognostic (2.23e-2)" "unprognostic (4.43e-2)" "unprognostic (1.49e-1)" "unprognostic (1.87e-3)" "unprognostic (3.99e-1)" "unprognostic (1.28e-1)" "unprognostic (1.26e-1)" "unprognostic (6.19e-2)" "unprognostic (1.31e-2)" "unprognostic (7.58e-2)" EPHB3 "ETK2, Hek2, Tyro6" ENSG00000182580 "EPH receptor B3" P54753 3 184561785-184582408 "Cancer-related genes, Enzymes, Predicted membrane proteins" "Angiogenesis, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 49.5" "Cell type enhanced" "Detected in many" "Breast secretory cells: 63.1;Enteric stem cells: 76.4;Esophageal apical cells: 136.7;Esophageal suprabasal cells: 58.0;Gastric chief cells: 64.4;Hofbauer cells: 51.2;Mucous neck cells: 106.5;Ocular epithelial cells: 81.3;Paneth cells: 92.8;Parietal cells: 77.8;Suprabasal keratinocytes: 62.2;Tuft cells: 46.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007698, HPA008184, CAB034350" Enhanced NA NA 180000 "Cluster 58: Skin - Keratinization" "Cluster 37: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 100: Stratified epithelial cells - Barrier functions" 5 "CAB034350: , HPA007698: , HPA008184: " "unprognostic (1.30e-2)" "unprognostic (5.77e-2)" "unprognostic (6.50e-2)" "unprognostic (4.00e-1)" "unprognostic (2.40e-1)" "unprognostic (3.67e-2)" "unprognostic (1.24e-1)" "unprognostic (2.04e-1)" "unprognostic (9.58e-2)" "unprognostic (2.59e-3)" "unprognostic (1.95e-2)" "unprognostic (5.32e-2)" "unprognostic (2.83e-1)" "unprognostic (2.02e-1)" "unprognostic (1.29e-3)" "unprognostic (1.80e-1)" "potential prognostic favorable (5.01e-4)" "unprognostic (2.06e-1)" "unprognostic (4.63e-2)" "unprognostic (4.37e-2)" "potential prognostic favorable (1.91e-4)" "unprognostic (2.88e-1)" "unprognostic (2.77e-2)" "unprognostic (2.12e-3)" "unprognostic (5.24e-2)" "unprognostic (2.26e-3)" "unprognostic (6.82e-2)" "unprognostic (3.93e-3)" "unprognostic (6.59e-2)" EPHB4 "HTK, Tyro11" ENSG00000196411 "EPH receptor B4" P54760 7 100802565-100827523 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Angiogenesis "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 106.0;Lymphatic endothelial cells: 95.7;Syncytiotrophoblasts: 292.3;Vascular endothelial cells: 73.8" "Cell type enriched" "Detected in some" 4 "endothelial cell: 26.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 2.0;neutrophil: 4.3" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Pituitary gland - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB013537 Uncertain NA NA 1700000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 75: Ovary - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 24 "CAB013537: " "unprognostic (2.33e-1)" "unprognostic (6.93e-3)" "unprognostic (1.77e-1)" "potential prognostic unfavorable (4.44e-4)" "unprognostic (1.28e-3)" "unprognostic (7.61e-2)" "unprognostic (2.45e-2)" "unprognostic (1.20e-2)" "unprognostic (2.20e-2)" "unprognostic (1.47e-1)" "potential prognostic favorable (2.20e-4)" "unprognostic (4.99e-3)" "unprognostic (3.85e-2)" "unprognostic (1.64e-1)" "unprognostic (6.68e-3)" "unprognostic (6.19e-2)" "unprognostic (4.15e-3)" "unprognostic (5.98e-2)" "unprognostic (5.42e-2)" "unprognostic (5.19e-2)" "unprognostic (2.79e-1)" "unprognostic (1.03e-3)" "unprognostic (7.20e-2)" "unprognostic (1.74e-1)" "unprognostic (7.34e-2)" "unprognostic (3.67e-1)" "unprognostic (2.20e-1)" "unprognostic (2.15e-1)" "unprognostic (8.75e-2)" "unprognostic (8.71e-3)" "unprognostic (2.87e-2)" EPHB6 HEP ENSG00000106123 "EPH receptor B6" 7 142855061-142871094 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 69.8;skin 1: 79.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 43.7;Brain inhibitory neurons: 51.6;Cholangiocytes: 38.7;Mesothelial cells: 61.3;Müller glia: 137.0;Prostatic glandular cells: 57.3;Suprabasal keratinocytes: 82.4" "Cell type enhanced" "Detected in all" "MGE interneuron: 104.9" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in all" 4 "basal ganglia: 70.9;cerebral cortex: 120.2;white matter: 83.2" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA035784 Uncertain "Nuclear speckles" "Intracellular and membrane" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 2: Non-specific - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 35: Neurons - Synaptic function & neurogenesis" 5 "Nuclear speckles" "HPA035784: " "unprognostic (3.97e-2)" "unprognostic (1.92e-2)" "unprognostic (5.16e-3)" "unprognostic (1.11e-1)" "unprognostic (4.98e-2)" "unprognostic (5.69e-2)" "unprognostic (1.71e-2)" "unprognostic (8.63e-2)" "unprognostic (3.33e-3)" "unprognostic (2.17e-1)" "potential prognostic favorable (1.20e-6)" "unprognostic (4.08e-2)" "unprognostic (1.11e-1)" "unprognostic (2.78e-2)" "unprognostic (9.11e-3)" "unprognostic (6.67e-2)" "unprognostic (2.16e-1)" "unprognostic (2.18e-3)" "unprognostic (2.07e-1)" "unprognostic (1.53e-1)" "unprognostic (8.33e-3)" "unprognostic (3.12e-3)" "unprognostic (3.54e-1)" "unprognostic (6.68e-2)" "unprognostic (5.29e-2)" "unprognostic (1.58e-1)" "unprognostic (1.23e-1)" "unprognostic (2.18e-1)" "unprognostic (8.03e-2)" EPHX1 EPHX ENSG00000143819 "Epoxide hydrolase 1" P07099 1 225810124-225845563 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Aromatic hydrocarbons catabolism, Detoxification, Lipid metabolism" Hydrolase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 1147.0;liver: 1594.1" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 608.5;Hepatocytes: 1002.0;Oocytes: 557.2;Ovarian stromal cells: 344.8;Respiratory ciliated cells: 325.9;Respiratory secretory cells: 355.2" "Cell type enhanced" "Detected in all" "fibroblast: 139.5;pericyte: 153.9" "Cancer enriched" "Detected in all" 5 "Liver Hepatocellular Carcinoma (TCGA): 2047.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "classical monocyte: 2.6" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Testis - Leydig cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020593, HPA048847" Enhanced NA NA 300000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 76: Non-specific - Metabolism" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 7: Liver cancer - Metabolism" "Cluster 18: Adrenal cortex cells - Steroidogensis" 21 "HPA020593: , HPA048847: " "unprognostic (2.66e-1)" "potential prognostic unfavorable (8.17e-4)" "unprognostic (1.04e-1)" "unprognostic (3.21e-1)" "unprognostic (1.30e-1)" "unprognostic (1.45e-1)" "unprognostic (3.88e-1)" "unprognostic (1.19e-2)" "unprognostic (6.27e-2)" "unprognostic (4.71e-3)" "validated prognostic favorable (2.35e-4)" "validated prognostic favorable (6.57e-4)" "unprognostic (4.90e-3)" "unprognostic (4.65e-2)" "potential prognostic favorable (2.65e-4)" "potential prognostic favorable (5.52e-6)" "unprognostic (1.19e-1)" "unprognostic (1.23e-1)" "unprognostic (2.35e-1)" "unprognostic (1.78e-2)" "unprognostic (4.07e-1)" "unprognostic (2.61e-1)" "unprognostic (7.06e-2)" "unprognostic (1.16e-2)" "unprognostic (6.22e-3)" "unprognostic (1.24e-1)" "unprognostic (5.46e-2)" "unprognostic (3.87e-1)" "unprognostic (1.59e-1)" "unprognostic (4.44e-2)" "unprognostic (1.17e-1)" EPHX2 "ABHD20, sEH" ENSG00000120915 "Epoxide hydrolase 2" P34913 8 27490781-27545564 "Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Aromatic hydrocarbons catabolism, Detoxification, Lipid metabolism" "Hydrolase, Multifunctional enzyme" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 311.3" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 224.3;Enterocytes: 378.4;Epididymal efferent duct absorptive cells: 140.1;Hepatocytes: 166.3;Proximal tubule cells: 139.8" "Cell type enhanced" "Detected in all" "ependymal cell: 64.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory CD4 T-cell: 35.1;naive CD4 T-cell: 107.0;naive CD8 T-cell: 50.6;T-reg: 29.7" "Lineage enriched" "Detected in many" 23 "T-cells: 107.0" "Cancer enhanced" "Detected in all" "prostate cancer: 37.9" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023094, HPA023660" Enhanced Enhanced Cytosol NA NA 1200000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 36: Choroid plexus - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 1: Enterocytes - Absorption and Digestion" Cytosol "HPA023094: , HPA023660: " "unprognostic (8.99e-2)" "unprognostic (2.08e-1)" "unprognostic (7.43e-3)" "unprognostic (4.42e-3)" "unprognostic (1.13e-3)" "unprognostic (3.02e-1)" "unprognostic (3.71e-2)" "unprognostic (1.23e-2)" "unprognostic (1.38e-2)" "unprognostic (8.70e-2)" "validated prognostic favorable (1.91e-8)" "validated prognostic favorable (3.56e-4)" "potential prognostic favorable (7.06e-4)" "unprognostic (1.66e-3)" "potential prognostic favorable (3.45e-6)" "unprognostic (1.01e-2)" "unprognostic (1.94e-2)" "unprognostic (2.12e-1)" "unprognostic (1.04e-1)" "unprognostic (3.18e-1)" "unprognostic (1.83e-1)" "unprognostic (2.95e-3)" "unprognostic (3.87e-3)" "unprognostic (1.59e-1)" "unprognostic (1.59e-1)" "unprognostic (2.31e-2)" "unprognostic (2.03e-1)" "unprognostic (6.97e-2)" "unprognostic (1.88e-1)" "unprognostic (2.45e-1)" "unprognostic (1.17e-1)" EPHX3 "ABHD9, FLJ22408" ENSG00000105131 "Epoxide hydrolase 3" Q9H6B9 19 15226919-15233435 "Enzymes, Predicted intracellular proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "cervix: 26.2;esophagus: 66.3;lymphoid tissue: 25.1;skin 1: 73.7;vagina: 35.0" "Group enriched" "Detected in many" 5 "Esophageal apical cells: 607.4;Esophageal suprabasal cells: 198.5" "Group enriched" "Detected in some" 4 "pericyte: 7.0;vascular associated smooth muscle cell: 2.1" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 56.7" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.9;non-classical monocyte: 2.4" "Group enriched" "Detected in many" 19 "dendritic cells: 1.3;monocytes: 2.4" "Cancer enhanced" "Detected in some" "Bile duct cancer: 5.7;testis cancer: 3.1" "Prostate - Urothelial cells, Spleen - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA012842 Uncertain Approved Nucleoplasm NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 1 Nucleoplasm "HPA012842: " "unprognostic (1.04e-1)" "unprognostic (2.69e-1)" "unprognostic (2.46e-2)" "unprognostic (2.14e-2)" "unprognostic (9.62e-2)" "potential prognostic favorable (4.04e-5)" "unprognostic (9.08e-2)" "unprognostic (2.25e-1)" "unprognostic (5.78e-2)" "unprognostic (9.13e-3)" "unprognostic (4.12e-2)" "unprognostic (4.41e-2)" "unprognostic (8.78e-2)" "unprognostic (1.38e-1)" "unprognostic (1.27e-1)" "unprognostic (6.05e-2)" "unprognostic (1.95e-2)" "unprognostic (1.98e-2)" "unprognostic (1.26e-1)" "unprognostic (1.51e-1)" "unprognostic (2.17e-1)" "unprognostic (2.12e-2)" "unprognostic (3.41e-1)" "unprognostic (4.02e-2)" "unprognostic (9.28e-2)" EPHX4 "ABHD7, EH4, EPHXRP, FLJ90341" ENSG00000172031 "Epoxide hydrolase 4" Q8IUS5 1 92029985-92063538 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 14.2;choroid plexus: 6.6" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 10.6;Brain excitatory neurons: 20.2;Brain inhibitory neurons: 37.1;Endometrial secretory cells: 13.0;Oocytes: 9.2;Respiratory secretory cells: 9.6;Retinal amacrine cells: 41.9;Retinal ganglion cells: 23.2;Smooth muscle cells: 12.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 12.1" "Lineage enriched" "Detected in single" 22 "T-cells: 12.1" "Low cancer specificity" "Detected in many" "Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA035067 Uncertain Approved Vesicles NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 53: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Neurons - Synaptic function & neurogenesis" 6 Vesicles "HPA035067: " "unprognostic (7.83e-2)" "unprognostic (2.14e-1)" "unprognostic (3.44e-1)" "unprognostic (7.98e-2)" "unprognostic (1.34e-1)" "unprognostic (1.04e-1)" "unprognostic (1.57e-1)" "unprognostic (3.02e-1)" "unprognostic (1.10e-1)" "unprognostic (3.89e-2)" "unprognostic (4.88e-2)" "unprognostic (2.80e-2)" "unprognostic (3.43e-2)" "unprognostic (1.69e-1)" "unprognostic (9.79e-2)" "unprognostic (6.39e-2)" "unprognostic (2.03e-1)" "potential prognostic unfavorable (6.05e-4)" "unprognostic (2.83e-2)" "unprognostic (5.08e-3)" "unprognostic (3.27e-2)" "unprognostic (4.73e-3)" "unprognostic (8.72e-2)" "unprognostic (3.39e-1)" "unprognostic (4.51e-2)" EPM2A "LD, LDE" ENSG00000112425 "EPM2A glucan phosphatase, laforin" O95278 6 145382535-145736023 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Autophagy, Carbohydrate metabolism, Glycogen metabolism" "Hydrolase, Protein phosphatase" "Disease variant, Epilepsy, Glycogen storage disease, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 71.9;tongue: 74.2" "Cell type enhanced" "Detected in many" "Astrocytes: 147.6;Myonuclei: 294.0;Retinal horizontal cells: 238.4;Tuft cells: 760.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 2.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053643, HPA055468" Supported Nucleoplasm NA NA "Cluster 18: Non-specific - Translation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 95: Tuft cells - Chemosensory signaling" 18 Nucleoplasm "HPA053643: , HPA055468: " "unprognostic (9.25e-2)" "unprognostic (1.46e-2)" "unprognostic (9.54e-2)" "unprognostic (3.72e-2)" "unprognostic (1.39e-1)" "unprognostic (2.28e-1)" "unprognostic (3.93e-3)" "unprognostic (1.72e-1)" "unprognostic (1.54e-1)" "unprognostic (1.75e-1)" "validated prognostic favorable (7.46e-7)" "validated prognostic favorable (2.13e-4)" "potential prognostic favorable (1.02e-4)" "unprognostic (2.42e-2)" "unprognostic (3.44e-3)" "unprognostic (3.88e-2)" "unprognostic (4.04e-2)" "unprognostic (1.51e-1)" "unprognostic (1.06e-1)" "unprognostic (3.87e-2)" "unprognostic (1.26e-1)" "potential prognostic favorable (2.46e-4)" "unprognostic (2.02e-2)" "unprognostic (1.11e-1)" "unprognostic (3.54e-1)" "unprognostic (1.12e-1)" "unprognostic (1.31e-1)" "potential prognostic unfavorable (1.64e-4)" "unprognostic (5.71e-2)" "unprognostic (3.20e-2)" "unprognostic (3.15e-1)" EPM2AIP1 "FLJ11207, KIAA0766" ENSG00000178567 "EPM2A interacting protein 1" Q7L775 3 36985043-36993131 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 32: Basophils - Transcription" "Cluster 65: Brain - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Transcription" 48 "potential prognostic favorable (1.24e-5)" "unprognostic (7.64e-2)" "unprognostic (3.09e-1)" "unprognostic (2.02e-1)" "unprognostic (1.80e-2)" "unprognostic (1.73e-2)" "unprognostic (1.85e-1)" "unprognostic (1.27e-1)" "unprognostic (3.80e-3)" "unprognostic (2.59e-3)" "unprognostic (5.48e-3)" "unprognostic (7.63e-2)" "unprognostic (7.72e-3)" "unprognostic (3.44e-1)" "unprognostic (8.01e-3)" "unprognostic (4.44e-3)" "unprognostic (2.67e-1)" "unprognostic (1.79e-1)" "unprognostic (2.47e-1)" "unprognostic (1.35e-1)" "unprognostic (2.01e-1)" "unprognostic (4.97e-2)" "unprognostic (6.28e-2)" "unprognostic (2.37e-1)" "unprognostic (1.91e-1)" "unprognostic (2.08e-1)" "unprognostic (1.46e-1)" "unprognostic (3.98e-2)" "unprognostic (9.65e-2)" "unprognostic (9.97e-3)" "unprognostic (1.19e-1)" EPN1 ENSG00000063245 "Epsin 1" Q9Y6I3 19 55675226-55709858 "Plasma proteins, Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 366.6;Esophageal apical cells: 237.5;Kupffer cells: 254.2;Late spermatids: 315.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009729, HPA061136, HPA071503" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" No No "Cluster 25: Non-specific - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 1: Enterocytes - Absorption and Digestion" 33 "Plasma membrane, Cytosol" "Nucleoplasm, Vesicles" "CAB009729: , HPA061136: , HPA071503: " "unprognostic (3.79e-2)" "unprognostic (1.25e-1)" "unprognostic (1.01e-1)" "unprognostic (1.10e-2)" "unprognostic (4.96e-2)" "unprognostic (1.28e-1)" "unprognostic (1.13e-1)" "unprognostic (1.62e-1)" "unprognostic (3.20e-1)" "unprognostic (2.91e-2)" "unprognostic (1.38e-1)" "unprognostic (4.54e-1)" "unprognostic (2.56e-3)" "unprognostic (1.81e-3)" "unprognostic (7.60e-2)" "potential prognostic unfavorable (6.45e-4)" "unprognostic (8.04e-3)" "unprognostic (1.57e-1)" "unprognostic (1.71e-1)" "unprognostic (2.63e-1)" "unprognostic (1.27e-1)" "unprognostic (1.62e-1)" "unprognostic (1.31e-1)" "unprognostic (2.08e-2)" "unprognostic (1.33e-1)" "unprognostic (4.90e-2)" "unprognostic (3.34e-2)" "unprognostic (1.16e-2)" "unprognostic (1.46e-1)" "unprognostic (1.58e-3)" "unprognostic (7.22e-2)" EPN2 "EHB21, KIAA1065" ENSG00000072134 "Epsin 2" O95208 17 19215615-19336715 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte progenitor cells: 1696.4;Oligodendrocytes: 431.7" "Cell type enhanced" "Detected in all" "oligodendrocyte precursor cell: 1848.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 13.4;eosinophil: 28.4;neutrophil: 8.6" "Lineage enriched" "Detected in many" 8 "granulocytes: 28.4" "Cancer enhanced" "Detected in all" "testis cancer: 117.5" "Spleen - Endothelial cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049809, HPA053360" Approved Supported Vesicles NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 42: Non-specific - Unknown function" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 17 Vesicles "HPA049809: , HPA053360: " "unprognostic (2.77e-1)" "unprognostic (2.49e-3)" "unprognostic (4.34e-2)" "potential prognostic unfavorable (4.76e-4)" "unprognostic (2.77e-1)" "potential prognostic unfavorable (1.01e-4)" "unprognostic (1.16e-1)" "potential prognostic favorable (8.89e-4)" "unprognostic (4.58e-3)" "unprognostic (8.47e-3)" "potential prognostic favorable (1.48e-4)" "unprognostic (3.27e-3)" "unprognostic (8.16e-2)" "unprognostic (1.84e-3)" "unprognostic (1.83e-2)" "unprognostic (1.70e-1)" "unprognostic (6.82e-2)" "unprognostic (2.37e-1)" "unprognostic (5.05e-2)" "unprognostic (2.64e-2)" "unprognostic (5.42e-2)" "unprognostic (2.55e-1)" "potential prognostic unfavorable (7.39e-4)" "unprognostic (2.24e-1)" "unprognostic (2.69e-1)" "unprognostic (1.18e-1)" "unprognostic (2.01e-1)" "unprognostic (2.53e-1)" "unprognostic (2.55e-1)" "unprognostic (2.08e-1)" "unprognostic (1.62e-2)" EPN3 "FLJ20778, MGC129899" ENSG00000049283 "Epsin 3" Q9H201 17 50532682-50543750 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 34.8;skin 1: 30.1;stomach 1: 34.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 89.5;Esophageal apical cells: 132.4;Esophageal basal cells: 31.7;Esophageal suprabasal cells: 45.4;Foveolar cells: 38.1;Gastric chief cells: 31.7;Granulosa cells: 33.3;Migrating cytotrophoblasts: 44.9;Parietal cells: 63.6;Prostatic club cells: 32.2;Salivary duct cells: 32.7" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 6.2;lower rhombic lip: 6.5;mammillary body: 4.2;thalamic excitatory: 5.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 48.6" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA055546, HPA063224" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 3 Vesicles Nucleoplasm "HPA055546: , HPA063224: " "unprognostic (3.79e-1)" "unprognostic (1.31e-3)" "unprognostic (4.42e-2)" "unprognostic (6.01e-3)" "unprognostic (2.61e-1)" "unprognostic (1.11e-1)" "unprognostic (2.05e-1)" "unprognostic (3.63e-1)" "unprognostic (1.18e-1)" "unprognostic (6.31e-2)" "unprognostic (8.23e-2)" "unprognostic (2.86e-1)" "unprognostic (5.11e-2)" "unprognostic (5.15e-2)" "unprognostic (7.76e-2)" "unprognostic (2.48e-2)" "unprognostic (3.52e-2)" "unprognostic (3.60e-2)" "unprognostic (1.52e-1)" "unprognostic (6.38e-3)" "unprognostic (1.17e-1)" "unprognostic (2.61e-1)" "unprognostic (4.57e-2)" "unprognostic (7.69e-2)" EPO EP ENSG00000130427 Erythropoietin P01588 7 100720468-100723700 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Erythrocyte maturation" Hormone "Cancer-related genes, Congenital erythrocytosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 34.4" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 3.2;Extravillous trophoblasts: 18.4;Hepatic stellate cells: 6.5;Hepatocytes: 6.8;Migrating cytotrophoblasts: 3.6;Pancreatic acinar cells: 21.6;Syncytiotrophoblasts: 3.1;Undifferentiated spermatogonia: 2.5" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "Kidney Renal Clear Cell Carcinoma (TCGA): 10.7;Liver Hepatocellular Carcinoma (TCGA): 2.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "liver cancer: 1.0" "Minor Salivary Gland - Minor salivary glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" CAB010336 Supported "Secreted to blood" Hormone NA NA 12300 "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 18: Liver cancer - Metabolism" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 6 "CAB010336: " "unprognostic (3.40e-1)" "unprognostic (2.73e-1)" "unprognostic (1.20e-2)" "unprognostic (3.65e-2)" "potential prognostic unfavorable (2.74e-5)" "unprognostic (1.82e-3)" EPOP "C17orf96, LOC100170841, PRR28" ENSG00000273604 "Elongin BC and polycomb repressive complex 2 associated protein" A6NHQ4 17 38671703-38674957 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 13.5;testis: 11.1" "Cell type enhanced" "Detected in some" "Bergmann glia: 1.4;Brain excitatory neurons: 1.9;Brain inhibitory neurons: 2.0;Oligodendrocyte progenitor cells: 1.6" "Cell type enhanced" "Detected in many" "deep-layer intratelencephalic: 8.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA055190, HPA056555" Enhanced Supported "Nucleoplasm,Cytosol,Cytoplasmic bodies" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" 14 Nucleoplasm "Cytosol, Cytoplasmic bodies" "HPA055190: , HPA056555: " "unprognostic (9.73e-2)" "unprognostic (1.31e-1)" "unprognostic (1.00e-2)" "unprognostic (2.74e-3)" "unprognostic (2.36e-2)" "unprognostic (2.83e-1)" "unprognostic (2.49e-2)" "unprognostic (2.11e-1)" "potential prognostic unfavorable (3.15e-5)" "unprognostic (6.17e-3)" "unprognostic (1.90e-3)" "unprognostic (2.90e-1)" "unprognostic (1.35e-2)" "unprognostic (1.98e-1)" "unprognostic (2.34e-2)" "unprognostic (3.63e-3)" "unprognostic (1.42e-2)" "unprognostic (2.15e-2)" "unprognostic (1.38e-1)" "unprognostic (5.95e-2)" "unprognostic (5.00e-2)" "unprognostic (3.06e-2)" "unprognostic (1.32e-1)" "unprognostic (7.80e-2)" "unprognostic (1.45e-1)" "unprognostic (4.40e-2)" EPOR ENSG00000187266 "Erythropoietin receptor" P19235 19 11377207-11384342 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" Receptor "Cancer-related genes, Congenital erythrocytosis, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 125.8;Hofbauer cells: 103.5;Platelets: 98.8;Renal collecting duct principal cells: 47.2" "Cell type enhanced" "Detected in all" "astrocyte: 24.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077654 Supported "Nuclear speckles,Plasma membrane" "Intracellular and membrane" Receptor NA Yes "Cluster 35: Neutrophils - Protein binding" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 16: Non-specific - Transcription" "Cluster 47: Leukemia - Hemostasis" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 20 "Plasma membrane" "Nuclear speckles" "HPA077654: " "unprognostic (6.99e-2)" "unprognostic (2.81e-1)" "unprognostic (1.64e-1)" "unprognostic (4.71e-2)" "unprognostic (1.28e-1)" "unprognostic (4.01e-1)" "unprognostic (1.01e-1)" "unprognostic (7.42e-2)" "unprognostic (4.23e-2)" "unprognostic (1.17e-1)" "potential prognostic unfavorable (1.87e-4)" "unprognostic (1.99e-1)" "unprognostic (4.77e-1)" "unprognostic (6.64e-2)" "unprognostic (5.72e-2)" "unprognostic (7.62e-2)" "unprognostic (5.87e-2)" "unprognostic (4.53e-3)" "unprognostic (1.86e-1)" "unprognostic (1.37e-1)" "unprognostic (7.58e-2)" "unprognostic (5.95e-3)" "potential prognostic unfavorable (5.13e-4)" "unprognostic (1.26e-2)" "unprognostic (1.61e-1)" "unprognostic (3.74e-1)" "unprognostic (1.46e-2)" "unprognostic (1.23e-1)" "unprognostic (2.14e-1)" "unprognostic (1.20e-1)" "unprognostic (9.21e-2)" EPPIN "CT71, dJ461P17.2, EPPIN1, EPPIN2, EPPIN3, SPINLW1, WAP7, WFDC7" ENSG00000101448 "Epididymal peptidase inhibitor" O95925 20 45540626-45547752 "Predicted intracellular proteins, Predicted secreted proteins" "Antimicrobial, Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "epididymis: 309.3" "Group enriched" "Detected in some" 4 "Epididymal principal cells: 65.8;Sertoli cells: 63.7" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 3.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Lung - Respiratory ciliated cells, Testis - Sertoli cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA067335 Supported "Secreted in male reproductive system" "Enzyme inhibitor" NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 72: Neuronal - Signal transduction" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 2 "HPA067335: " "unprognostic (2.18e-1)" "unprognostic (4.37e-2)" "unprognostic (1.04e-2)" "unprognostic (1.42e-1)" "unprognostic (2.84e-1)" "potential prognostic unfavorable (1.80e-4)" EPPIN-WFDC6 SPINLW1-WFDC6 ENSG00000249139 "EPPIN-WFDC6 readthrough" O95925 20 45534196-45547662 "Predicted secreted proteins" "Antimicrobial, Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 78 "epididymis: 60.2;testis: 50.1" "Group enriched" "Detected in some" 4 "Epididymal principal cells: 7.9;Respiratory ciliated cells: 12.4;Sertoli cells: 11.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA067335 Supported "Secreted in male reproductive system" "Enzyme inhibitor" NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 107: Ciliated cells - Cilia assembly & function" "HPA067335: " EPPK1 EPIPL1 ENSG00000261150 "Epiplakin 1" P58107 8 143857324-143878467 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 15.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 83.9;Basal keratinocytes: 124.4;Gastric progenitor cells: 70.5;Ocular epithelial cells: 101.2;Suprabasal keratinocytes: 207.3;Urothelial cells: 48.1" "Cell type enriched" "Detected in some" 5 "ependymal cell: 31.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 27.6" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Kidney - Macrophages, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Smooth muscle cells, Skin - Keratinocyte (granular), Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA066808, HPA067357, HPA069333" Approved Enhanced "Intermediate filaments" NA NA 11000000 "Cluster 9: Skin - Hair follicle development" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 26: Keratinocytes - Keratinization" 23 "Intermediate filaments" "HPA066808: , HPA067357: , HPA069333: " "unprognostic (1.15e-1)" "unprognostic (2.76e-1)" "unprognostic (7.81e-2)" "unprognostic (3.46e-1)" "unprognostic (2.60e-2)" "unprognostic (1.41e-1)" "unprognostic (1.83e-1)" "potential prognostic favorable (2.17e-4)" "unprognostic (1.67e-2)" "unprognostic (4.62e-3)" "unprognostic (1.49e-2)" "unprognostic (4.23e-2)" "unprognostic (1.54e-1)" "unprognostic (6.66e-2)" "unprognostic (2.80e-2)" "unprognostic (1.47e-1)" "unprognostic (1.70e-1)" "unprognostic (5.08e-3)" "unprognostic (3.89e-1)" "unprognostic (1.14e-1)" "unprognostic (6.59e-3)" "unprognostic (1.56e-1)" "unprognostic (1.96e-2)" "unprognostic (3.68e-1)" "unprognostic (9.40e-3)" "unprognostic (1.25e-1)" EPRS1 "EARS, EPRS, GLUPRORS, PARS, QARS, QPRS" ENSG00000136628 "Glutamyl-prolyl-tRNA synthetase 1" P07814 1 219968600-220046530 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis, Translation regulation" "Aminoacyl-tRNA synthetase, Ligase, Multifunctional enzyme, RNA-binding" "Disease variant, Leukodystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Salivary acinar cells: 250.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026490, HPA030052" Enhanced Supported "Cytosol,Mid piece" NA NA 610000 "Cluster 33: Non-specific - ATP binding" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 73 Cytosol "Mid piece" "HPA026490: , HPA030052: " "unprognostic (7.73e-2)" "unprognostic (1.13e-2)" "potential prognostic unfavorable (9.92e-4)" "unprognostic (2.94e-2)" "unprognostic (2.14e-1)" "unprognostic (4.17e-3)" "unprognostic (2.63e-1)" "unprognostic (3.64e-2)" "unprognostic (3.93e-3)" "potential prognostic favorable (1.55e-5)" "unprognostic (2.09e-1)" "unprognostic (6.15e-3)" "unprognostic (1.54e-3)" "unprognostic (2.10e-2)" "unprognostic (1.31e-3)" "unprognostic (1.82e-1)" "unprognostic (3.68e-1)" "unprognostic (1.34e-1)" "potential prognostic unfavorable (2.10e-4)" "unprognostic (1.18e-2)" "unprognostic (2.99e-1)" "unprognostic (4.69e-2)" "unprognostic (3.03e-2)" "unprognostic (3.25e-2)" "unprognostic (2.89e-1)" "unprognostic (1.36e-1)" "unprognostic (1.36e-1)" "unprognostic (2.74e-2)" "unprognostic (4.49e-2)" EPS15 "AF-1P, MLLT5" ENSG00000085832 "Epidermal growth factor receptor pathway substrate 15" P42566 1 51354263-51519328 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Endocytosis, Host-virus interaction, Protein transport, Transport" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Melanocytes: 745.5;Neutrophils: 753.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Fibroblasts, Spleen - Endothelial cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008451, CAB010164, HPA061431" Approved Enhanced Vesicles,Cytosol NA NA 32000 "Cluster 16: Non-specific - Cell proliferation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 34: Non-specific - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 90 "Vesicles, Cytosol" "CAB010164: , HPA008451: , HPA061431: " "unprognostic (5.26e-2)" "unprognostic (9.54e-2)" "unprognostic (2.98e-2)" "potential prognostic unfavorable (3.85e-4)" "unprognostic (1.19e-1)" "unprognostic (2.18e-2)" "unprognostic (2.21e-1)" "unprognostic (5.90e-2)" "unprognostic (1.97e-1)" "unprognostic (1.05e-2)" "potential prognostic favorable (4.59e-5)" "unprognostic (6.53e-2)" "unprognostic (8.28e-2)" "unprognostic (2.39e-3)" "unprognostic (1.64e-1)" "unprognostic (3.06e-1)" "unprognostic (1.02e-2)" "unprognostic (9.64e-3)" "unprognostic (3.71e-2)" "unprognostic (1.14e-1)" "unprognostic (6.27e-2)" "unprognostic (1.57e-1)" "unprognostic (2.45e-1)" "unprognostic (2.16e-1)" "unprognostic (1.57e-1)" "unprognostic (2.26e-1)" "unprognostic (3.79e-2)" "unprognostic (6.49e-2)" "unprognostic (3.00e-1)" "unprognostic (1.55e-1)" "potential prognostic unfavorable (5.71e-5)" EPS15L1 eps15R ENSG00000127527 "Epidermal growth factor receptor pathway substrate 15 like 1" Q9UBC2 19 16355239-16472085 "Plasma proteins, Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 253.0;Neutrophils: 324.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019237, HPA055309" Approved Approved Vesicles NA NA 67000 "Cluster 32: Basophils - Transcription" "Cluster 24: Non-specific - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 48 Vesicles "HPA019237: , HPA055309: " "unprognostic (5.32e-2)" "unprognostic (7.79e-2)" "unprognostic (8.90e-2)" "unprognostic (9.82e-3)" "unprognostic (4.08e-1)" "unprognostic (9.63e-2)" "unprognostic (2.72e-1)" "unprognostic (2.32e-1)" "unprognostic (1.86e-1)" "unprognostic (1.00e-1)" "unprognostic (3.67e-1)" "unprognostic (1.37e-2)" "unprognostic (1.14e-1)" "unprognostic (4.98e-3)" "unprognostic (1.48e-2)" "unprognostic (2.82e-1)" "unprognostic (5.79e-2)" "unprognostic (1.07e-1)" "unprognostic (3.28e-2)" "unprognostic (5.44e-3)" "unprognostic (5.48e-2)" "unprognostic (1.31e-2)" "potential prognostic unfavorable (1.61e-4)" "unprognostic (3.01e-3)" "unprognostic (8.55e-2)" "unprognostic (1.24e-3)" "unprognostic (4.58e-3)" "unprognostic (1.03e-2)" "unprognostic (3.40e-1)" "unprognostic (2.29e-1)" "unprognostic (9.28e-2)" EPS8 ENSG00000151491 "Epidermal growth factor receptor pathway substrate 8" Q12929 12 15620134-15882329 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Colonocytes: 904.6;Endometrial glandular cells: 883.7;Pericytes: 1360.2;Renal collecting duct intercalated cells: 1398.5" "Group enriched" "Detected in all" 4 "pericyte: 3175.1;vascular associated smooth muscle cell: 1605.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 22.3" "Lineage enriched" "Detected in all" 4 "monocytes: 22.3" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Breast - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003897, HPA050209" Approved Approved "Plasma membrane" NA NA 16000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 49: Hindbrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 110: Mural cells - ECM organization" 41 "Plasma membrane" "HPA003897: , HPA050209: " "unprognostic (2.66e-2)" "unprognostic (9.97e-2)" "unprognostic (6.66e-2)" "unprognostic (9.17e-2)" "unprognostic (1.39e-1)" "unprognostic (6.95e-2)" "unprognostic (3.14e-1)" "unprognostic (2.60e-2)" "unprognostic (6.29e-2)" "potential prognostic unfavorable (2.73e-4)" "potential prognostic favorable (8.22e-8)" "unprognostic (1.18e-3)" "unprognostic (6.70e-2)" "unprognostic (1.89e-1)" "unprognostic (4.71e-2)" "unprognostic (8.65e-2)" "unprognostic (1.64e-1)" "unprognostic (2.27e-1)" "unprognostic (1.88e-1)" "unprognostic (1.44e-2)" "unprognostic (1.12e-2)" "validated prognostic unfavorable (2.87e-6)" "validated prognostic unfavorable (3.68e-5)" "unprognostic (3.41e-1)" "unprognostic (1.24e-2)" "unprognostic (6.94e-3)" "unprognostic (9.68e-2)" "unprognostic (1.90e-2)" "unprognostic (6.47e-2)" "unprognostic (3.26e-2)" "unprognostic (4.50e-2)" EPS8L1 "DRC3, FLJ20258, MGC23164, MGC4642" ENSG00000131037 "EPS8 like 1" Q8TE68 19 55072020-55087923 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 120.5;skin 1: 59.2" "Group enriched" "Detected in many" 4 "Esophageal apical cells: 1809.3;Syncytiotrophoblasts: 624.4" "Cell type enhanced" "Detected in some" "endothelial cell: 2.3;pericyte: 2.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "eosinophil: 2.3" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Liver - Cholangiocytes, Skin - Keratinocyte (granular), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041851, HPA043545" Uncertain Supported Cytosol NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 15: Kidney cancer - Membrane components" "Cluster 84: Apical squamous epithelium - Cornification" 17 Cytosol "HPA041851: , HPA043545: " "unprognostic (2.64e-1)" "unprognostic (2.12e-1)" "unprognostic (1.69e-2)" "unprognostic (2.19e-2)" "unprognostic (6.41e-2)" "unprognostic (1.42e-1)" "unprognostic (4.78e-2)" "unprognostic (4.25e-2)" "unprognostic (3.41e-3)" "unprognostic (7.97e-2)" "unprognostic (1.60e-2)" "unprognostic (1.96e-1)" "unprognostic (4.24e-2)" "unprognostic (2.42e-2)" "unprognostic (4.74e-2)" "unprognostic (2.19e-2)" "unprognostic (5.51e-2)" "unprognostic (1.99e-1)" "unprognostic (1.84e-1)" "unprognostic (3.42e-3)" "unprognostic (1.35e-1)" "unprognostic (1.18e-2)" "unprognostic (2.56e-1)" "unprognostic (4.38e-2)" "unprognostic (2.16e-1)" "unprognostic (1.54e-2)" "unprognostic (1.92e-1)" "unprognostic (1.72e-1)" "unprognostic (2.40e-1)" EPS8L2 "FLJ21935, FLJ22171, MGC3088" ENSG00000177106 "EPS8 like 2" Q9H6S3 11 694438-727727 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 184.2" "Cell type enriched" "Detected in many" 4 "Esophageal apical cells: 1188.6" "Cell type enhanced" "Detected in many" "deep-layer near-projecting: 54.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.4" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Breast - Breast glandular cells, Lung - Alveolar cells type 1, Skeletal muscle - Fibroblasts, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Region enriched" "Detected in some" 10 "cerebellum: 12.2" HPA041143 Approved Supported Centrosome,Cytosol NA NA 3900 "Cluster 11: Esophagus - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 15 "Centrosome, Cytosol" "HPA041143: " "unprognostic (1.27e-1)" "unprognostic (4.30e-2)" "unprognostic (1.86e-1)" "unprognostic (1.59e-3)" "unprognostic (1.08e-1)" "potential prognostic favorable (1.78e-4)" "potential prognostic unfavorable (9.28e-4)" "unprognostic (1.13e-3)" "unprognostic (2.65e-1)" "unprognostic (4.86e-2)" "potential prognostic favorable (1.76e-6)" "unprognostic (6.82e-3)" "unprognostic (1.68e-2)" "unprognostic (1.06e-2)" "unprognostic (9.97e-2)" "unprognostic (2.86e-1)" "unprognostic (4.40e-1)" "unprognostic (3.23e-3)" "unprognostic (1.32e-1)" "unprognostic (6.20e-3)" "unprognostic (5.72e-1)" "unprognostic (6.14e-3)" "unprognostic (2.60e-3)" "unprognostic (6.90e-2)" "unprognostic (2.75e-2)" "unprognostic (1.89e-1)" "unprognostic (1.74e-1)" "unprognostic (3.93e-2)" "unprognostic (1.05e-1)" "unprognostic (8.92e-2)" "unprognostic (2.45e-1)" EPS8L3 "FLJ21522, MGC16817" ENSG00000198758 "EPS8 like 3" Q8TE67 1 109750080-109764027 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "gallbladder: 33.5;intestine: 133.8;stomach 1: 47.9" "Cell type enhanced" "Detected in some" "Colonocytes: 199.9;Enteric stem cells: 90.3;Enteric transient amplifying cells: 101.2;Enterocytes: 330.2;Foveolar cells: 62.8;Goblet cells: 106.6;Late spermatids: 265.3;Neuroendocrine cells: 56.7;Paneth cells: 85.1;Tuft cells: 149.9" "Not detected" "Not detected" "Group enriched" "Detected in many" 8 "Colon Adenocarcinoma (TCGA): 100.4;Pancreatic Adenocarcinoma (TCGA): 58.8;Rectum Adenocarcinoma (TCGA): 98.7;Stomach Adenocarcinoma (TCGA): 51.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 65.2;Gastric cancer: 30.1" "Colon - Colon enterocytes, Heart muscle - Cardiomyocytes, Pancreas - Ductal cells, Stomach - Gastric mucous cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA030998 Approved Approved Vesicles NA NA "Cluster 77: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" Vesicles "HPA030998: " "unprognostic (1.21e-2)" "unprognostic (2.37e-1)" "unprognostic (1.37e-1)" "potential prognostic favorable (1.45e-4)" "unprognostic (9.83e-3)" "unprognostic (1.16e-1)" "unprognostic (1.10e-2)" "potential prognostic unfavorable (2.14e-6)" "unprognostic (8.17e-3)" "potential prognostic unfavorable (8.29e-5)" "unprognostic (2.34e-1)" "unprognostic (9.24e-2)" "unprognostic (1.12e-1)" "unprognostic (8.36e-3)" "unprognostic (1.59e-1)" "unprognostic (1.21e-2)" "unprognostic (7.71e-2)" "unprognostic (2.80e-2)" EPSTI1 "BRESI1, MGC29634" ENSG00000133106 "Epithelial stromal interaction 1" Q96J88 13 42886388-42992271 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "cDC: 130.9;Enterocytes: 167.2;Extravillous trophoblasts: 292.0;Macrophages: 133.2;Megakaryocyte-Erythroid progenitors: 148.3;Microglia: 171.0;Oocytes: 142.8" "Group enriched" "Detected in many" 6 "central nervous system macrophage: 228.5;endothelial cell: 317.8;fibroblast: 103.3;leukocyte: 80.2;pericyte: 154.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Thyroid gland - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA017362 Approved NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 82: Dendritic cells - Antigen presentation" 1 "HPA017362: " "unprognostic (1.55e-1)" "unprognostic (2.89e-1)" "unprognostic (4.37e-2)" "unprognostic (2.27e-1)" "unprognostic (2.55e-1)" "unprognostic (1.15e-1)" "unprognostic (2.25e-1)" "unprognostic (2.25e-1)" "unprognostic (4.74e-2)" "unprognostic (1.89e-1)" "potential prognostic favorable (2.12e-4)" "unprognostic (3.79e-1)" "unprognostic (1.40e-1)" "unprognostic (1.08e-1)" "unprognostic (2.15e-2)" "unprognostic (2.74e-2)" "unprognostic (4.40e-2)" "unprognostic (5.89e-2)" "unprognostic (3.46e-1)" "unprognostic (7.50e-2)" "unprognostic (1.76e-1)" "validated prognostic unfavorable (6.59e-4)" "validated prognostic unfavorable (3.87e-4)" "unprognostic (1.00e-1)" "unprognostic (1.68e-1)" "potential prognostic favorable (7.70e-4)" "unprognostic (3.18e-1)" "unprognostic (2.88e-1)" "unprognostic (3.07e-2)" "unprognostic (3.85e-2)" "unprognostic (2.05e-2)" EPX "EPO, EPP, EPX-PEN" ENSG00000121053 "Eosinophil peroxidase" P11678 17 58192726-58205174 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Hydrogen peroxide" "Oxidoreductase, Peroxidase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "bone marrow: 31.7" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 4.2;Brain inhibitory neurons: 3.3;Fallopian tube ciliated cells: 3.5;Monocyte progenitors: 5.0;Other brain neurons: 3.2;Retinal amacrine cells: 5.7;Sertoli cells: 3.9" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 23 "eosinophil: 2.2" "Lineage enriched" "Detected in single" 23 "granulocytes: 2.2" "Group enriched" "Detected in some" 25 "Leukemia: 7.7;lymphoma: 18.4" "Lung - Neutrophils_1, Spleen - Neutrophils_1" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA076792 Enhanced NA NA 4000000 "Cluster 22: Eosinophils - Transcription" "Cluster 15: Bone marrow - Innate immune response" "Cluster 37: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 98: Neurons - Neurotransmission & signaling" 1 "HPA076792: " EPYC "DSPG3, Pg-Lb, SLRR3B" ENSG00000083782 Epiphycan Q99645 12 90963682-91005026 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "placenta: 6.0" "Cell type enhanced" "Detected in some" "Decidual stromal cells: 2.3;Fibro-adipogenic progenitors: 1.4;Late primary spermatocytes: 1.1;Late spermatids: 1.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 13.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "Rhabdoid: 25.9;Sarcoma: 10.8" "Prostate - Fibroblasts, Skin - Hair cortex cells, Skin - Inner root sheath cells" "Region enhanced" "Detected in single" "midbrain: 1.4" "Low region specificity" "Detected in all" "HPA038212, HPA045455" Approved "Secreted to extracellular matrix" "No annotated function" NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 108: Fibroblasts - ECM organization" 2 "HPA038212: , HPA045455: " "unprognostic (1.67e-1)" "unprognostic (1.56e-1)" "unprognostic (6.75e-2)" "unprognostic (3.08e-3)" "unprognostic (1.66e-1)" "unprognostic (1.50e-1)" "unprognostic (3.40e-1)" "unprognostic (1.26e-3)" "unprognostic (3.06e-2)" "unprognostic (2.10e-2)" "unprognostic (8.33e-2)" "unprognostic (1.82e-1)" "unprognostic (1.47e-3)" "unprognostic (1.58e-1)" "unprognostic (1.32e-2)" "potential prognostic unfavorable (2.90e-4)" "unprognostic (1.68e-1)" "unprognostic (2.54e-1)" "unprognostic (4.25e-3)" "unprognostic (3.56e-2)" "unprognostic (5.66e-2)" EQTN "AFAF, C9orf11, equatorin, SPACA8" ENSG00000120160 Equatorin Q9NQ60 9 27284654-27297150 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 52 "testis: 35.3" "Group enriched" "Detected in some" 18 "Early spermatids: 757.8;Late primary spermatocytes: 553.5" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 5.1;oligodendrocyte: 5.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "HPA015089, HPA015504" Enhanced Approved "Plasma membrane,Actin filaments" "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" "Plasma membrane, Actin filaments" "HPA015089: , HPA015504: " "potential prognostic favorable (7.63e-4)" ERAL1 HERA-B ENSG00000132591 "Era like 12S mitochondrial rRNA chaperone 1" O75616 17 28855010-28861061 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ribosome biogenesis" "RNA-binding, rRNA-binding" "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 80.5;Extravillous trophoblasts: 65.1;Migrating cytotrophoblasts: 71.8;Oocytes: 64.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021425, HPA024423" Supported Enhanced Mitochondria,Cytosol NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 54 Mitochondria Cytosol "HPA021425: , HPA024423: " "unprognostic (2.99e-2)" "unprognostic (4.87e-2)" "unprognostic (9.45e-2)" "unprognostic (1.56e-1)" "unprognostic (9.89e-2)" "unprognostic (4.61e-1)" "unprognostic (3.72e-1)" "unprognostic (1.22e-2)" "unprognostic (1.52e-2)" "unprognostic (2.66e-1)" "unprognostic (1.16e-3)" "unprognostic (1.86e-1)" "unprognostic (4.37e-2)" "validated prognostic unfavorable (4.78e-4)" "validated prognostic unfavorable (9.15e-6)" "unprognostic (2.88e-2)" "unprognostic (1.59e-1)" "unprognostic (5.92e-3)" "unprognostic (3.43e-2)" "unprognostic (1.88e-1)" "unprognostic (2.58e-1)" "unprognostic (6.57e-2)" "unprognostic (4.16e-2)" "unprognostic (3.11e-1)" "unprognostic (2.16e-2)" "unprognostic (1.71e-2)" "unprognostic (1.22e-2)" "unprognostic (2.28e-1)" "unprognostic (1.78e-1)" "unprognostic (2.52e-1)" "unprognostic (5.85e-2)" ERAP1 "A-LAP, ARTS-1, ERAAP1, KIAA0525, PILS-AP" ENSG00000164307 "Endoplasmic reticulum aminopeptidase 1" Q9NZ08 5 96760810-96808100 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Cardiomyocytes: 643.9;Epicardial cells: 1557.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025095, HPA042317" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" Immunity NA NA 3520000 34000000 "Cluster 1: T-cells - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 30: White matter - Myelination" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 2 "Nucleoplasm, Cytosol" "Plasma membrane" "CAB025095: , HPA042317: " "potential prognostic favorable (6.96e-5)" "unprognostic (2.40e-2)" "unprognostic (3.87e-1)" "unprognostic (6.32e-2)" "unprognostic (5.42e-3)" "unprognostic (3.83e-1)" "unprognostic (8.28e-2)" "unprognostic (7.79e-2)" "unprognostic (2.68e-1)" "unprognostic (6.36e-3)" "unprognostic (3.79e-3)" "unprognostic (1.65e-1)" "unprognostic (4.54e-2)" "unprognostic (1.98e-2)" "unprognostic (8.79e-2)" "unprognostic (1.99e-1)" "unprognostic (2.42e-1)" "unprognostic (4.16e-2)" "unprognostic (2.90e-1)" "unprognostic (1.61e-1)" "unprognostic (2.66e-3)" "unprognostic (3.62e-2)" "unprognostic (2.28e-1)" "unprognostic (1.94e-1)" "unprognostic (7.44e-2)" "unprognostic (6.55e-2)" "unprognostic (4.20e-2)" "unprognostic (6.33e-2)" "unprognostic (2.18e-2)" "unprognostic (3.30e-2)" "unprognostic (5.61e-2)" ERAP2 "L-RAP, LRAP" ENSG00000164308 "Endoplasmic reticulum aminopeptidase 2" Q6P179 5 96875986-96919703 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 46.5" "Cell type enhanced" "Detected in many" "B-cells: 107.9;Plasma cells: 99.7;T-cells: 88.1" "Cell type enhanced" "Detected in all" "endothelial cell: 58.8;leukocyte: 131.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB025618, HPA034498, HPA064360" Enhanced Approved "Golgi apparatus" "Secreted to blood" Immunity NA NA 13000000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 30: White matter - Myelination" "Cluster 15: Kidney cancer - Membrane components" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 2 "Golgi apparatus" "CAB025618: , HPA034498: , HPA064360: " "unprognostic (1.14e-1)" "unprognostic (1.63e-1)" "unprognostic (1.80e-1)" "unprognostic (2.13e-1)" "unprognostic (2.23e-1)" "unprognostic (4.04e-2)" "unprognostic (2.03e-1)" "unprognostic (1.86e-1)" "unprognostic (5.12e-2)" "unprognostic (1.88e-1)" "unprognostic (6.48e-2)" "unprognostic (1.16e-1)" "unprognostic (2.66e-3)" "unprognostic (7.36e-3)" "unprognostic (2.20e-1)" "unprognostic (1.88e-2)" "potential prognostic unfavorable (1.50e-4)" "unprognostic (1.10e-1)" "unprognostic (7.39e-2)" "unprognostic (2.25e-1)" "unprognostic (1.02e-1)" "potential prognostic unfavorable (1.11e-4)" "unprognostic (8.67e-2)" "unprognostic (9.96e-2)" "unprognostic (2.16e-2)" "unprognostic (2.71e-3)" "unprognostic (5.03e-2)" "unprognostic (1.05e-1)" "unprognostic (2.77e-2)" "unprognostic (3.10e-1)" "unprognostic (2.17e-1)" ERAS "HRAS2, HRASP" ENSG00000187682 "ES cell expressed Ras" Q7Z444 X 48826513-48830138 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.2" "Cell type enhanced" "Detected in some" "Astrocytes: 1.5;Bergmann glia: 1.5;Brain inhibitory neurons: 1.4;Differentiating spermatogonia: 2.2;Early primary spermatocytes: 2.8;Gastric progenitor cells: 1.3;Hepatocytes: 1.4;Oligodendrocytes: 1.1;Other brain neurons: 2.2;Paneth cells: 3.9;Sertoli cells: 3.4" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in some" 5 "Ovary Serous Cystadenocarcinoma (TCGA): 2.4;Testicular Germ Cell Tumor (TCGA): 1.4;Uterine Corpus Endometrial Carcinoma (TCGA): 5.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Myeloma: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in single" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 98: Neurons - Neurotransmission & signaling" 1 "unprognostic (1.22e-2)" "unprognostic (4.49e-2)" "unprognostic (1.95e-1)" "unprognostic (2.49e-1)" ERBB2 "c-ERB-2, c-ERB2, CD340, HER-2, HER2, MLN-19, NEU, NGL, p185(erbB2)" ENSG00000141736 "Erb-b2 receptor tyrosine kinase 2" P04626 17 39687914-39730426 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Transcription, Transcription regulation" "Activator, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 241.3;Prostatic club cells: 178.9" "Group enriched" "Detected in many" 4 "astrocyte: 27.0;Bergmann glia: 16.9;choroid plexus epithelial cell: 15.4;ependymal cell: 55.2;fibroblast: 34.0;pericyte: 14.2;vascular associated smooth muscle cell: 20.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 5.0" "Group enriched" "Detected in many" 5 "granulocytes: 1.2;T-cells: 5.0" "Group enriched" "Detected in all" 5 "breast cancer: 705.7;Esophageal cancer: 445.4;Gastric cancer: 199.3" "Adrenal gland - Fibroblasts, Breast - Breast glandular cells, Lung - Alveolar cells type 1, Pituitary gland - Undifferentiated cells (Pituitary gland), Spleen - Fibroblasts_1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB000043, HPA001060, HPA001338, HPA001383, HPA007983, CAB020416, CAB062555" Enhanced Enhanced "Nucleoplasm,Plasma membrane,Cytosol" NA NA 360000 "Cluster 24: Non-specific - Transcription" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 202 "Plasma membrane" "Nucleoplasm, Cytosol" "CAB000043: , CAB020416: , CAB062555: , HPA001060: , HPA001338: , HPA001383: , HPA007983: " "unprognostic (6.10e-2)" "unprognostic (5.53e-2)" "unprognostic (4.02e-2)" "unprognostic (2.28e-1)" "unprognostic (5.11e-3)" "unprognostic (2.48e-1)" "unprognostic (7.78e-2)" "potential prognostic unfavorable (7.20e-5)" "unprognostic (2.40e-2)" "unprognostic (1.18e-1)" "potential prognostic favorable (1.76e-8)" "unprognostic (1.16e-3)" "unprognostic (5.15e-3)" "unprognostic (8.44e-2)" "unprognostic (5.43e-2)" "unprognostic (3.03e-1)" "unprognostic (1.06e-2)" "unprognostic (1.99e-1)" "unprognostic (1.94e-1)" "potential prognostic unfavorable (6.98e-4)" "unprognostic (5.27e-1)" "potential prognostic unfavorable (6.95e-4)" "unprognostic (1.50e-1)" "unprognostic (1.40e-1)" "unprognostic (1.56e-2)" "unprognostic (1.78e-1)" "unprognostic (2.07e-2)" "unprognostic (8.31e-2)" "unprognostic (2.00e-1)" "unprognostic (1.04e-1)" "unprognostic (1.76e-1)" ERBB3 "HER3, LCCS2" ENSG00000065361 "Erb-b2 receptor tyrosine kinase 3" P21860 12 56076799-56103505 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Enterocytes: 111.6;Esophageal apical cells: 275.6;Oligodendrocytes: 307.1" "Group enriched" "Detected in many" 17 "committed oligodendrocyte precursor: 315.9;oligodendrocyte: 330.4;oligodendrocyte precursor cell: 87.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.0" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Breast - Breast glandular cells, Colon - Enteric glia cells, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Skin - Keratinocyte (granular), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025331, HPA045396, HPA070524" Approved Supported "Plasma membrane,Actin filaments" "Secreted - unknown location" Receptor NA NA 240000 "Cluster 77: Intestine - Digestion" "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 80: Oligodendrocytes - Myelination" 102 "Plasma membrane" "Actin filaments" "CAB025331: , HPA045396: , HPA070524: " "unprognostic (7.09e-2)" "unprognostic (1.97e-1)" "unprognostic (5.39e-2)" "unprognostic (3.58e-1)" "unprognostic (2.12e-2)" "unprognostic (9.74e-3)" "unprognostic (4.38e-1)" "unprognostic (2.72e-3)" "unprognostic (2.11e-2)" "unprognostic (5.50e-2)" "validated prognostic favorable (6.64e-5)" "validated prognostic favorable (4.22e-4)" "unprognostic (4.51e-2)" "potential prognostic unfavorable (2.29e-4)" "unprognostic (3.71e-3)" "unprognostic (1.76e-1)" "unprognostic (1.37e-1)" "unprognostic (3.94e-1)" "unprognostic (6.19e-2)" "unprognostic (2.13e-2)" "unprognostic (5.93e-2)" "unprognostic (1.13e-2)" "unprognostic (4.00e-2)" "unprognostic (2.44e-1)" "unprognostic (3.75e-2)" "unprognostic (1.42e-1)" "unprognostic (1.47e-1)" "unprognostic (9.29e-2)" "unprognostic (1.67e-1)" "unprognostic (1.77e-2)" "unprognostic (6.29e-2)" ERBB4 "ALS19, HER4" ENSG00000178568 "Erb-b2 receptor tyrosine kinase 4" Q15303 2 211375717-212538841 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Lactation, Transcription, Transcription regulation" "Activator, Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Amyotrophic lateral sclerosis, Cancer-related genes, Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 7.6;brain: 7.7;fallopian tube: 10.6" "Cell type enhanced" "Detected in many" "Astrocytes: 3533.4;Brain inhibitory neurons: 3028.7;Breast hormone-responsive cells: 2747.5;Corticotrophs: 2166.6;Distal convoluted tubule cells: 6347.8;Loop of henle epithelial cells: 3889.2;Oligodendrocyte progenitor cells: 3083.7;Pituicytes/FSCs: 10589.5;Renal connecting tubule cells: 3168.3;Sertoli cells: 5848.0" "Cell type enhanced" "Detected in all" "CGE interneuron: 8806.8;eccentric medium spiny neuron: 8570.1;LAMP5-LHX6 and Chandelier: 11575.6;MGE interneuron: 8483.6" "Cancer enhanced" "Detected in some" "Breast Invasive Carcinoma (TCGA): 7.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 4.0" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Skin - Eccrine sweat gland cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000276, HPA012016, CAB025522" Enhanced NA NA 170000 "Cluster 65: Brain - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 61 "CAB000276: , CAB025522: , HPA012016: " "unprognostic (1.71e-1)" "unprognostic (8.96e-2)" "unprognostic (2.79e-1)" "unprognostic (2.37e-1)" "unprognostic (2.88e-2)" "unprognostic (1.34e-1)" "unprognostic (2.80e-2)" "unprognostic (1.63e-1)" "unprognostic (1.99e-1)" "unprognostic (6.81e-3)" ERBIN "ERBB2IP, LAP2" ENSG00000112851 "Erbb2 interacting protein" Q96RT1 5 65883128-66082546 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 1130.9;Oligodendrocytes: 1371.3" "Cell type enhanced" "Detected in all" "oligodendrocyte: 1720.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048606, HPA059863" Approved Supported "Plasma membrane,Cell Junctions" NA NA 16000 "Cluster 35: Neutrophils - Protein binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 42 "Plasma membrane, Cell Junctions" "HPA048606: , HPA059863: " "potential prognostic favorable (4.28e-4)" "unprognostic (2.52e-1)" "unprognostic (4.15e-2)" "unprognostic (2.70e-1)" "unprognostic (2.86e-2)" "unprognostic (3.80e-1)" "unprognostic (1.62e-2)" "unprognostic (1.31e-2)" "unprognostic (6.03e-2)" "potential prognostic favorable (8.24e-7)" "unprognostic (4.09e-2)" "unprognostic (2.08e-1)" "unprognostic (1.22e-1)" "unprognostic (1.95e-2)" "unprognostic (2.53e-2)" "unprognostic (2.86e-1)" "unprognostic (3.70e-1)" "unprognostic (9.77e-2)" "unprognostic (4.60e-2)" "unprognostic (2.85e-3)" "unprognostic (6.85e-2)" "unprognostic (2.27e-1)" "unprognostic (4.12e-1)" "unprognostic (8.89e-2)" "unprognostic (7.79e-2)" "unprognostic (2.66e-2)" "unprognostic (3.56e-1)" "unprognostic (9.50e-2)" "unprognostic (2.34e-1)" ERC1 "CAST2, ELKS, KIAA1081, MGC12974, RAB6IP2" ENSG00000082805 "ELKS/RAB6-interacting/CAST family member 1" Q8IUD2 12 990509-1495933 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Lactotrophs: 1227.9;Thyrotrophs: 1727.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Smooth muscle cells, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019513, HPA019523, HPA024130" Approved Approved "Vesicles,Plasma membrane,Centrosome" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 74: Non-specific - Signal transduction" "Cluster 25: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 25 "Plasma membrane" "Vesicles, Centrosome" "HPA019513: , HPA019523: , HPA024130: " "unprognostic (5.44e-2)" "unprognostic (2.09e-1)" "unprognostic (2.14e-2)" "unprognostic (9.70e-3)" "unprognostic (4.84e-1)" "unprognostic (2.32e-1)" "unprognostic (1.88e-1)" "unprognostic (4.32e-2)" "unprognostic (6.69e-2)" "potential prognostic unfavorable (6.46e-4)" "potential prognostic favorable (3.62e-6)" "unprognostic (5.28e-2)" "unprognostic (8.57e-2)" "unprognostic (3.11e-2)" "unprognostic (2.41e-1)" "unprognostic (7.26e-2)" "unprognostic (9.63e-2)" "unprognostic (6.40e-2)" "unprognostic (8.17e-2)" "unprognostic (3.45e-2)" "unprognostic (6.10e-2)" "unprognostic (9.31e-2)" "unprognostic (7.35e-3)" "unprognostic (1.62e-1)" "unprognostic (3.95e-2)" "unprognostic (1.90e-2)" "unprognostic (2.03e-1)" "unprognostic (4.43e-2)" "unprognostic (4.84e-1)" "unprognostic (3.38e-2)" "unprognostic (3.96e-1)" ERC2 "CAST, CAST1, ELKSL, KIAA0378, SPBC110, Spc110" ENSG00000187672 "ELKS/RAB6-interacting/CAST family member 2" O15083 3 55508311-56469095 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 9.6" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 950.1;Brain inhibitory neurons: 625.8;Cone photoreceptor cells: 546.5;Lactotrophs: 770.0;Oligodendrocyte progenitor cells: 468.2;Other brain neurons: 1049.6;Pituitary stem cells: 334.0;Retinal amacrine cells: 367.5;Retinal ganglion cells: 397.9;Somatotrophs: 1247.4;Thyrotrophs: 1295.3" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Rhabdoid: 1.6" "Adipose visceral - Mesothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073739 Enhanced NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" 9 "HPA073739: " "potential prognostic favorable (7.39e-6)" "unprognostic (9.63e-3)" ERCC1 RAD10 ENSG00000012061 "ERCC excision repair 1, endonuclease non-catalytic subunit" P07992 19 45407334-45478828 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" DNA-binding "Cancer-related genes, Cataract" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Epicardial cells: 5321.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004390, HPA029773, HPA050182, CAB072859, CAB072860" Supported Supported Nucleoplasm NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 35: Non-specific - Mixed function" "Cluster 45: Non-specific - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 31 Nucleoplasm "CAB004390: , CAB072859: , CAB072860: , HPA029773: , HPA050182: " "unprognostic (2.39e-1)" "unprognostic (1.56e-2)" "unprognostic (1.12e-1)" "unprognostic (1.47e-1)" "unprognostic (3.71e-2)" "unprognostic (1.28e-1)" "potential prognostic favorable (8.42e-4)" "unprognostic (1.51e-2)" "unprognostic (2.28e-1)" "unprognostic (5.28e-3)" "unprognostic (4.48e-2)" "unprognostic (2.42e-3)" "potential prognostic favorable (7.51e-4)" "potential prognostic unfavorable (5.03e-4)" "unprognostic (1.16e-2)" "unprognostic (2.12e-3)" "unprognostic (2.27e-2)" "unprognostic (8.58e-2)" "unprognostic (2.29e-1)" "unprognostic (1.15e-1)" "unprognostic (1.98e-2)" "unprognostic (3.79e-1)" "unprognostic (2.93e-1)" "unprognostic (4.47e-2)" "unprognostic (1.32e-1)" "unprognostic (1.02e-1)" "unprognostic (1.21e-1)" "unprognostic (2.39e-1)" "unprognostic (1.11e-1)" "unprognostic (2.62e-2)" "unprognostic (1.04e-1)" ERCC2 "EM9, MAG, MGC102762, MGC126218, MGC126219, XPD" ENSG00000104884 "ERCC excision repair 2, TFIIH core complex helicase subunit" P18074 19 45349837-45370918 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Chromosome partition, DNA damage, DNA repair, Host-virus interaction, Transcription, Transcription regulation" "DNA-binding, Helicase, Hydrolase, Isomerase" "Cancer-related genes, Cataract, Cockayne syndrome, Deafness, Disease variant, Dwarfism, Ichthyosis, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 48.9;Oocytes: 115.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005375, HPA038057, HPA069266" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 67: Testis - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 41: Oocytes - Oogenesis" 38 Nucleoplasm Cytosol "CAB005375: , HPA038057: , HPA069266: " "unprognostic (1.11e-1)" "unprognostic (1.93e-1)" "unprognostic (1.90e-1)" "unprognostic (1.65e-1)" "unprognostic (1.38e-1)" "unprognostic (1.97e-2)" "unprognostic (9.38e-2)" "unprognostic (2.39e-1)" "unprognostic (8.75e-3)" "unprognostic (1.98e-2)" "potential prognostic favorable (4.09e-5)" "unprognostic (4.11e-2)" "potential prognostic favorable (9.44e-4)" "unprognostic (2.92e-3)" "unprognostic (2.31e-3)" "unprognostic (6.35e-2)" "unprognostic (1.76e-1)" "unprognostic (1.73e-1)" "unprognostic (3.89e-2)" "unprognostic (8.02e-3)" "unprognostic (3.23e-3)" "unprognostic (3.05e-2)" "unprognostic (2.23e-1)" "unprognostic (1.57e-3)" "unprognostic (5.66e-2)" "unprognostic (3.70e-2)" "unprognostic (1.71e-1)" "unprognostic (2.04e-1)" "unprognostic (8.41e-2)" "unprognostic (3.25e-3)" "unprognostic (4.52e-2)" ERCC3 "BTF2, RAD25, Ssl2, XPB" ENSG00000163161 "ERCC excision repair 3, TFIIH core complex helicase subunit" P19447 2 127257290-127294166 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction, Transcription, Transcription regulation" "DNA-binding, Helicase, Hydrolase, Isomerase" "Cancer-related genes, Cockayne syndrome, Deafness, Disease variant, Dwarfism, Ichthyosis, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037153, HPA046077" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 7: Non-specific - Transcription" 92 Nucleoplasm Vesicles "CAB037153: , HPA046077: " "unprognostic (6.91e-3)" "unprognostic (6.88e-2)" "unprognostic (1.19e-1)" "unprognostic (1.05e-1)" "unprognostic (1.16e-1)" "unprognostic (8.82e-2)" "unprognostic (2.67e-1)" "unprognostic (2.29e-3)" "unprognostic (5.08e-3)" "unprognostic (1.15e-1)" "potential prognostic favorable (2.17e-5)" "unprognostic (1.68e-2)" "unprognostic (5.78e-2)" "potential prognostic unfavorable (3.43e-4)" "unprognostic (7.64e-2)" "unprognostic (1.04e-1)" "unprognostic (5.39e-2)" "unprognostic (1.86e-1)" "unprognostic (1.12e-1)" "unprognostic (2.54e-1)" "unprognostic (1.74e-1)" "unprognostic (4.10e-2)" "potential prognostic unfavorable (3.34e-4)" "unprognostic (2.29e-1)" "unprognostic (1.35e-1)" "unprognostic (2.41e-1)" "unprognostic (5.76e-2)" "unprognostic (4.12e-2)" "unprognostic (2.13e-1)" "unprognostic (1.12e-1)" "unprognostic (4.51e-2)" ERCC4 "FANCQ, RAD1, XPF" ENSG00000175595 "ERCC excision repair 4, endonuclease catalytic subunit" Q92889 16 13920138-13952348 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Endonuclease, Hydrolase, Nuclease" "Cancer-related genes, Cockayne syndrome, Disease variant, Dwarfism, Fanconi anemia, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 17.1" "Cell type enhanced" "Detected in many" "Early spermatids: 264.6;Late spermatids: 220.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000156, HPA045828" Approved Supported "Nucleoplasm,Nuclear bodies,Plasma membrane" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 31: Non-specific - Transcription" "Cluster 54: Non-specific - Transcription" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 27 "Nucleoplasm, Nuclear bodies" "Plasma membrane" "CAB000156: , HPA045828: " "unprognostic (9.55e-3)" "unprognostic (1.25e-1)" "unprognostic (1.36e-1)" "unprognostic (2.72e-2)" "unprognostic (1.72e-1)" "unprognostic (9.46e-2)" "unprognostic (1.77e-1)" "unprognostic (3.69e-1)" "unprognostic (5.88e-2)" "unprognostic (1.34e-1)" "potential prognostic favorable (2.94e-4)" "unprognostic (1.99e-2)" "unprognostic (2.24e-1)" "unprognostic (4.87e-3)" "unprognostic (2.58e-1)" "unprognostic (1.53e-1)" "unprognostic (5.40e-2)" "unprognostic (4.17e-1)" "unprognostic (3.03e-2)" "unprognostic (4.13e-2)" "potential prognostic unfavorable (4.59e-4)" "unprognostic (1.47e-1)" "unprognostic (1.69e-2)" "unprognostic (4.53e-1)" "unprognostic (3.30e-3)" "unprognostic (1.69e-1)" "unprognostic (1.84e-1)" "unprognostic (2.00e-1)" "unprognostic (3.37e-1)" "unprognostic (7.35e-3)" "unprognostic (8.99e-2)" ERCC5 "ERCM2, XPGC" ENSG00000134899 "ERCC excision repair 5, endonuclease" P28715 13 102845831-102875995 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Endonuclease, Hydrolase, Nuclease" "Cancer-related genes, Cockayne syndrome, Deafness, Disease variant, Dwarfism, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Astrocytes: 25.7;Bergmann glia: 39.3;Brain excitatory neurons: 42.7;Brain inhibitory neurons: 44.2;Choroid plexus epithelial cells: 35.6;Ependymal cells: 15.8;Microglia: 49.0;Oligodendrocyte progenitor cells: 34.1;Oligodendrocytes: 45.0;Other brain neurons: 35.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045845, HPA050374" Supported Supported Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 6: Non-specific - Immune response" "Cluster 19: Non-specific - Unknown function" "Cluster 22: Non-specific - Basic cellular functions" 15 Nucleoplasm "HPA045845: , HPA050374: " "unprognostic (1.49e-1)" "unprognostic (2.05e-1)" "unprognostic (1.07e-2)" "unprognostic (2.91e-2)" "unprognostic (6.49e-2)" "unprognostic (8.89e-2)" "unprognostic (9.17e-2)" "potential prognostic favorable (8.18e-4)" "unprognostic (2.35e-1)" "unprognostic (2.73e-1)" "validated prognostic favorable (4.22e-7)" "validated prognostic favorable (3.12e-4)" "unprognostic (9.13e-3)" "unprognostic (1.49e-1)" "unprognostic (1.08e-2)" "unprognostic (9.11e-2)" "unprognostic (6.24e-3)" "unprognostic (1.88e-2)" "unprognostic (1.27e-1)" "unprognostic (6.34e-2)" "unprognostic (1.03e-1)" "unprognostic (1.82e-3)" "unprognostic (1.96e-1)" "unprognostic (6.35e-2)" "unprognostic (1.21e-1)" "unprognostic (1.23e-1)" "unprognostic (6.39e-2)" "unprognostic (2.75e-1)" "unprognostic (7.31e-2)" "unprognostic (2.63e-2)" "unprognostic (8.43e-2)" ERCC6 "ARMD5, CKN2, CSB, RAD26" ENSG00000225830 "ERCC excision repair 6, chromatin remodeling factor" "P0DP91, Q03468" 10 49454168-49539538 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Neurogenesis, Transcription, Transcription regulation" "DNA-binding, Helicase, Hydrolase" "Age-related macular degeneration, Cancer-related genes, Cataract, Cockayne syndrome, Deafness, Disease variant, Dwarfism, Intellectual disability, Premature ovarian failure, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Choroid plexus epithelial cells: 159.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" HPA071297 Supported "Nucleoplasm,Nuclear bodies" Yes No "Cluster 7: Non-specific - Innate immune response" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 7: Non-specific - Transcription" 64 Nucleoplasm "Nuclear bodies" "HPA071297: " "potential prognostic unfavorable (4.61e-4)" "unprognostic (7.93e-2)" "unprognostic (1.35e-1)" "unprognostic (1.13e-1)" "unprognostic (3.13e-1)" "unprognostic (1.05e-3)" "unprognostic (1.20e-1)" "potential prognostic favorable (5.20e-4)" "unprognostic (1.35e-1)" "unprognostic (6.34e-2)" "validated prognostic favorable (5.61e-5)" "validated prognostic favorable (8.76e-4)" "unprognostic (2.84e-1)" "unprognostic (9.98e-2)" "unprognostic (3.63e-1)" "unprognostic (3.57e-1)" "unprognostic (1.82e-1)" "unprognostic (1.34e-1)" "unprognostic (4.97e-2)" "potential prognostic unfavorable (3.85e-4)" "unprognostic (4.97e-3)" "unprognostic (4.72e-3)" "unprognostic (7.77e-2)" "unprognostic (5.75e-2)" "unprognostic (3.77e-2)" "unprognostic (4.51e-2)" "unprognostic (8.02e-2)" "unprognostic (2.52e-1)" "unprognostic (1.27e-1)" "unprognostic (2.45e-1)" ERCC6L "FLJ20105, PICH, RAD26L" ENSG00000186871 "ERCC excision repair 6 like, spindle assembly checkpoint helicase" Q2NKX8 X 72204657-72239027 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 3.0;lymphoid tissue: 3.3" "Cell type enhanced" "Detected in many" "Adipocytes: 15.0;Cardiomyocytes: 32.1;Epicardial cells: 31.8;Erythrocyte progenitors: 24.1;Fibro-adipogenic progenitors: 16.9;Megakaryocyte progenitors: 13.6;Monocyte progenitors: 14.8;Myonuclei: 14.0;Myosatellite cells: 10.8" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 15.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "NK-cell: 1.7" "Lineage enriched" "Detected in single" 4 "NK-cells: 1.7" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA050492 Approved Uncertain Nucleoplasm,Centrosome,Cytosol No Yes "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 48: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 15 Centrosome "Nucleoplasm, Cytosol" "HPA050492: " "unprognostic (6.11e-2)" "unprognostic (1.18e-3)" "unprognostic (1.11e-1)" "unprognostic (9.01e-2)" "unprognostic (2.43e-1)" "unprognostic (2.08e-1)" "unprognostic (2.41e-1)" "unprognostic (1.80e-1)" "unprognostic (4.68e-1)" "validated prognostic unfavorable (1.43e-4)" "validated prognostic unfavorable (1.95e-5)" "unprognostic (2.04e-2)" "unprognostic (1.54e-1)" "unprognostic (1.20e-1)" "unprognostic (1.74e-1)" "unprognostic (5.13e-3)" "potential prognostic favorable (8.43e-4)" "unprognostic (3.36e-2)" "unprognostic (4.65e-2)" "unprognostic (7.60e-3)" "unprognostic (1.45e-1)" "unprognostic (3.84e-2)" ERCC6L2 "C9orf102, FLJ37706, HEBO, RAD26L" ENSG00000182150 "ERCC excision repair 6 like 2" Q5T890 9 95871264-96121154 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "HPA021259, HPA021260, HPA021271, HPA022422" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 9: Non-specific - Receptor signaling" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 94: Gonadal somatic cells - Mixed function" 3 "Nucleoplasm, Cytosol" "HPA021259: , HPA021260: , HPA021271: , HPA022422: " "unprognostic (4.60e-2)" "unprognostic (1.69e-2)" "unprognostic (4.61e-2)" "unprognostic (1.22e-2)" "unprognostic (4.80e-3)" "unprognostic (1.20e-2)" "unprognostic (1.77e-2)" "unprognostic (9.15e-2)" "unprognostic (5.07e-2)" "potential prognostic favorable (8.09e-6)" "unprognostic (4.73e-3)" "unprognostic (4.67e-2)" "unprognostic (1.03e-1)" "unprognostic (7.20e-2)" "unprognostic (4.33e-2)" "unprognostic (1.58e-1)" "unprognostic (1.35e-2)" "unprognostic (1.71e-2)" "unprognostic (3.51e-2)" "unprognostic (1.68e-2)" "unprognostic (2.58e-1)" "unprognostic (5.27e-2)" "unprognostic (5.47e-3)" "unprognostic (5.27e-2)" "unprognostic (3.41e-1)" "unprognostic (2.59e-1)" "unprognostic (2.87e-1)" "unprognostic (5.60e-2)" "unprognostic (3.21e-2)" ERCC8 "CKN1, CSA" ENSG00000049167 "ERCC excision repair 8, CSA ubiquitin ligase complex subunit" Q13216 5 60866454-60945073 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Cockayne syndrome, Deafness, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Myonuclei: 144.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029328 Approved "Nuclear speckles" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 9: Non-specific - Receptor signaling" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 7: Non-specific - Transcription" 35 "Nuclear speckles" "HPA029328: " "unprognostic (1.21e-1)" "unprognostic (3.96e-2)" "unprognostic (8.54e-3)" "unprognostic (1.34e-1)" "unprognostic (1.88e-2)" "unprognostic (4.39e-2)" "unprognostic (8.01e-3)" "unprognostic (4.16e-2)" "unprognostic (6.73e-2)" "unprognostic (4.09e-3)" "potential prognostic favorable (7.29e-4)" "unprognostic (4.43e-1)" "unprognostic (1.33e-1)" "unprognostic (3.29e-2)" "unprognostic (1.15e-2)" "unprognostic (6.02e-2)" "unprognostic (1.91e-1)" "unprognostic (3.57e-2)" "unprognostic (2.21e-1)" "unprognostic (5.82e-3)" "unprognostic (6.23e-2)" "unprognostic (5.46e-2)" "unprognostic (2.54e-1)" "unprognostic (1.99e-1)" "unprognostic (5.21e-2)" "unprognostic (1.49e-2)" "unprognostic (1.78e-1)" "unprognostic (6.95e-2)" "unprognostic (2.04e-2)" "unprognostic (1.02e-1)" EREG ER ENSG00000124882 Epiregulin O14944 4 74365145-74388749 "Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Mitogen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "bone marrow: 121.5" "Cell type enhanced" "Detected in many" "cDC: 393.0;Esophageal apical cells: 833.0;Hematopoietic stem cells: 947.6;Megakaryocyte progenitors: 935.3;Megakaryocyte-Erythroid progenitors: 1194.8;Monocyte progenitors: 3242.6;monocytes: 3369.3;Neutrophil progenitors: 402.2" "Group enriched" "Detected in some" 36 "CGE interneuron: 10.8;leukocyte: 21.9" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 18.3;Rectum Adenocarcinoma (TCGA): 23.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 126.8" "Adipose visceral - Neutrophils, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA047186, HPA054373" Approved Vesicles,Cytosol "Secreted to blood" "Growth factor" NA NA 46000 "Cluster 15: Bone marrow - Innate immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 7 Vesicles Cytosol "HPA047186: , HPA054373: " "unprognostic (7.67e-2)" "unprognostic (1.26e-1)" "potential prognostic unfavorable (8.82e-6)" "unprognostic (4.04e-2)" "unprognostic (9.73e-3)" "unprognostic (2.06e-2)" "unprognostic (6.06e-2)" "unprognostic (5.07e-2)" "potential prognostic unfavorable (5.68e-4)" "unprognostic (6.14e-3)" "potential prognostic unfavorable (7.21e-4)" "unprognostic (2.95e-3)" "validated prognostic unfavorable (9.01e-5)" "validated prognostic unfavorable (3.99e-4)" "unprognostic (1.92e-2)" "potential prognostic favorable (2.50e-4)" "unprognostic (1.23e-2)" "unprognostic (4.65e-1)" ERF "PE-2, PE2" ENSG00000105722 "ETS2 repressor factor" P50548 19 42247569-42255128 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Epicardial cells: 6.8;Epididymal clear cells: 2.0;Fallopian secretory cells: 2.0;Fallopian tube ciliated cells: 1.8;Ocular epithelial cells: 1.7;Schwann cells: 3.7" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058532, HPA067952, HPA072144" Approved Supported "Nucleoplasm,Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 11: White matter - Signal transduction" "Cluster 4: Non-specific - Transcription" "Cluster 103: Non-specific - Basic cellular processes" 27 Nucleoplasm "Nucleoli, Plasma membrane, Cytosol" "HPA058532: , HPA067952: , HPA072144: " "unprognostic (5.96e-2)" "unprognostic (1.62e-2)" "unprognostic (4.04e-2)" "unprognostic (3.23e-3)" "unprognostic (1.68e-2)" "unprognostic (5.36e-3)" "unprognostic (7.73e-2)" "unprognostic (5.69e-2)" "unprognostic (1.54e-1)" "unprognostic (3.37e-1)" "potential prognostic favorable (3.29e-4)" "unprognostic (3.46e-2)" "unprognostic (6.25e-2)" "unprognostic (3.26e-1)" "unprognostic (1.74e-1)" "unprognostic (7.00e-3)" "unprognostic (2.16e-1)" "unprognostic (1.72e-1)" "unprognostic (3.07e-3)" "unprognostic (1.17e-1)" "unprognostic (1.91e-1)" "unprognostic (3.07e-1)" "unprognostic (8.94e-2)" "unprognostic (3.48e-1)" "unprognostic (2.40e-2)" "unprognostic (3.62e-2)" "unprognostic (1.22e-1)" "unprognostic (2.00e-1)" "unprognostic (4.99e-1)" "unprognostic (6.31e-3)" "unprognostic (5.58e-2)" ERFE "C1QTNF15, CTRP15, FAM132B, FLJ37034" ENSG00000178752 Erythroferrone Q4G0M1 2 238158970-238168900 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skeletal muscle: 14.1;testis: 12.4;thyroid gland: 23.1" "Group enriched" "Detected in some" 4 "Early spermatids: 52.0;Late primary spermatocytes: 67.9;Myosatellite cells: 25.8" "Cell type enhanced" "Detected in some" "deep-layer near-projecting: 6.8;miscellaneous: 2.9;upper rhombic lip: 3.5" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 31.9;Thyroid Carcinoma (TCGA): 49.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Uterine cancer: 25.9" "Breast - Endothelial cells, Spleen - Erythrocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Secreted to blood" Hormone NA NA 277000 "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 15: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 12 "unprognostic (7.36e-3)" "unprognostic (1.61e-1)" "unprognostic (3.92e-3)" "unprognostic (5.26e-3)" "unprognostic (4.04e-2)" "unprognostic (1.78e-1)" "potential prognostic unfavorable (1.43e-4)" "validated prognostic unfavorable (2.34e-5)" "validated prognostic unfavorable (7.74e-5)" "potential prognostic favorable (1.06e-5)" "unprognostic (1.06e-3)" "potential prognostic unfavorable (4.12e-4)" "unprognostic (1.55e-1)" "unprognostic (1.56e-3)" "unprognostic (4.43e-3)" "unprognostic (8.38e-2)" "unprognostic (1.33e-2)" "unprognostic (3.09e-3)" "unprognostic (1.67e-3)" "unprognostic (1.42e-1)" "unprognostic (2.70e-2)" "unprognostic (3.44e-1)" "unprognostic (3.65e-2)" "unprognostic (5.29e-2)" "unprognostic (3.31e-2)" "unprognostic (1.45e-2)" ERFL erfl1 ENSG00000268041 "ETS repressor factor like" A0A1W2PQ73 19 41907704-41928449 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "intestine: 2.6;lymphoid tissue: 2.9" "Cell type enhanced" "Detected in some" "B-cells: 2.6;Early primary spermatocytes: 3.2;Endometrial stromal cells: 2.7;Epicardial cells: 4.5;Gastric progenitor cells: 2.6;Granulosa cells: 2.4;Hematopoietic stem cells: 3.9;Medullary thymic epithelial cells: 7.2;NK-cells: 3.7;Retinal horizontal cells: 4.0;T-cells: 4.4;Thymocytes: 5.9" "Cell type enhanced" "Detected in some" "leukocyte: 4.2" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lymphoma: 3.5" "Adipose visceral - T-cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA072144 Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 5: Spleen - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 9: T-cells - Adaptive immunity: Regulation" "Nucleoplasm, Nucleoli" Cytosol "HPA072144: " "unprognostic (5.45e-2)" "unprognostic (7.06e-3)" "unprognostic (2.95e-1)" "unprognostic (1.43e-1)" ERG "erg-3, p55" ENSG00000157554 "ETS transcription factor ERG" P11308 21 38380027-38661780 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 38.4" "Cell type enhanced" "Detected in many" "Hematopoietic stem cells: 724.0;Lymphatic endothelial cells: 317.6;Mast cells: 136.2;Megakaryocyte-Erythroid progenitors: 261.0;Neutrophil progenitors: 685.0;Thymocytes: 195.6;Vascular endothelial cells: 559.5" "Cell type enriched" "Detected in many" 7 "endothelial cell: 838.9" "Group enriched" "Detected in all" 4 "Kidney Renal Clear Cell Carcinoma (TCGA): 17.4;Prostate Adenocarcinoma (TCGA): 40.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "Leukemia: 24.0;prostate cancer: 21.4" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Lung - Endothelial cells, Minor Salivary Gland - Endothelial cells, Pancreas - Endothelial cells, Pituitary gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Spleen - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018377, HPA046598" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 6: Leukemia - Signal transduction" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 83 Nucleoplasm Cytosol "CAB018377: , HPA046598: " "unprognostic (1.37e-1)" "unprognostic (1.74e-1)" "unprognostic (2.28e-1)" "potential prognostic unfavorable (2.11e-9)" "unprognostic (2.54e-3)" "unprognostic (2.35e-2)" "unprognostic (1.08e-1)" "unprognostic (1.33e-2)" "unprognostic (3.08e-1)" "unprognostic (8.97e-2)" "validated prognostic favorable (1.10e-8)" "validated prognostic favorable (2.10e-4)" "potential prognostic unfavorable (4.67e-5)" "unprognostic (2.98e-3)" "potential prognostic favorable (5.04e-4)" "unprognostic (9.66e-3)" "unprognostic (2.07e-1)" "unprognostic (6.24e-2)" "unprognostic (1.03e-1)" "unprognostic (6.17e-2)" "unprognostic (4.69e-2)" "unprognostic (1.37e-1)" "unprognostic (2.05e-1)" "unprognostic (1.80e-1)" "unprognostic (8.10e-2)" "unprognostic (3.53e-1)" "unprognostic (2.07e-1)" "unprognostic (1.65e-3)" "unprognostic (1.41e-1)" "unprognostic (6.48e-3)" "unprognostic (2.37e-1)" ERG28 "C14orf1, NET51" ENSG00000133935 "Ergosterol biosynthesis 28 homolog" Q9UKR5 14 75649791-75660876 "Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 203.2;Epididymal principal cells: 220.7;Esophageal apical cells: 312.6;Esophageal suprabasal cells: 275.7;Extravillous trophoblasts: 196.0;Granulosa cells: 204.4;Late primary spermatocytes: 347.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary gland basal cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043172 Approved NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 47: Testis - Mixed function" "Cluster 44: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 59 "HPA043172: " "unprognostic (5.32e-2)" "unprognostic (2.14e-1)" "unprognostic (9.19e-2)" "unprognostic (7.13e-2)" "unprognostic (1.71e-3)" "unprognostic (1.26e-1)" "unprognostic (3.76e-1)" "potential prognostic unfavorable (2.60e-4)" "unprognostic (2.90e-1)" "potential prognostic favorable (4.37e-4)" "unprognostic (2.49e-2)" "unprognostic (3.47e-2)" "unprognostic (8.80e-2)" "unprognostic (1.97e-2)" "unprognostic (8.54e-2)" "unprognostic (8.78e-2)" "unprognostic (3.41e-1)" "unprognostic (1.67e-1)" "unprognostic (1.69e-1)" "unprognostic (2.80e-1)" "unprognostic (2.32e-1)" "unprognostic (3.40e-1)" "unprognostic (1.87e-1)" "unprognostic (6.28e-3)" "unprognostic (9.23e-2)" "unprognostic (2.97e-2)" "unprognostic (4.09e-1)" "unprognostic (2.87e-2)" "unprognostic (1.46e-1)" ERGIC1 "ERGIC-32, ERGIC32, KIAA1181, NET24" ENSG00000113719 "Endoplasmic reticulum-golgi intermediate compartment 1" Q969X5 5 172834251-172952792 "Disease related genes, Human disease related genes, Predicted membrane proteins" "ER-Golgi transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 1218.5;Prostatic glandular cells: 469.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Spleen - Fibroblasts_2, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018666, HPA018900" Enhanced Enhanced Nucleoplasm,Vesicles NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 76: Non-specific - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 14 "Nucleoplasm, Vesicles" "HPA018666: , HPA018900: " "unprognostic (5.21e-3)" "unprognostic (2.98e-2)" "unprognostic (6.81e-2)" "unprognostic (5.33e-3)" "unprognostic (1.16e-2)" "unprognostic (5.19e-2)" "unprognostic (4.38e-1)" "potential prognostic unfavorable (9.93e-4)" "unprognostic (1.48e-2)" "unprognostic (6.12e-2)" "potential prognostic favorable (1.87e-4)" "unprognostic (1.43e-1)" "unprognostic (3.49e-2)" "unprognostic (6.79e-3)" "unprognostic (1.46e-1)" "unprognostic (3.78e-2)" "unprognostic (1.03e-1)" "unprognostic (7.90e-3)" "unprognostic (1.45e-1)" "unprognostic (2.70e-1)" "unprognostic (7.15e-3)" "unprognostic (4.53e-2)" "unprognostic (3.69e-1)" "unprognostic (1.84e-1)" "unprognostic (2.74e-2)" "unprognostic (3.99e-3)" "unprognostic (2.56e-1)" "unprognostic (2.80e-1)" "unprognostic (1.44e-1)" "unprognostic (4.56e-2)" "unprognostic (5.09e-2)" ERGIC2 "Erv41, PTX1" ENSG00000087502 "ERGIC and golgi 2" Q96RQ1 12 29337352-29381189 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 393.0;Late primary spermatocytes: 282.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049695 Approved Supported "Nucleoli rim,Golgi apparatus,Vesicles" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 38 "Golgi apparatus, Vesicles" "Nucleoli rim" "HPA049695: " "unprognostic (2.66e-1)" "unprognostic (1.28e-2)" "unprognostic (7.43e-2)" "unprognostic (1.48e-2)" "unprognostic (3.16e-2)" "unprognostic (2.92e-1)" "unprognostic (9.61e-2)" "unprognostic (6.01e-2)" "unprognostic (6.39e-3)" "unprognostic (1.17e-2)" "potential prognostic favorable (2.39e-5)" "unprognostic (7.96e-2)" "unprognostic (2.42e-2)" "unprognostic (1.56e-2)" "unprognostic (4.01e-3)" "unprognostic (2.84e-3)" "unprognostic (8.46e-3)" "unprognostic (1.41e-1)" "unprognostic (1.10e-1)" "unprognostic (1.56e-1)" "unprognostic (6.06e-2)" "validated prognostic unfavorable (7.14e-5)" "validated prognostic unfavorable (1.02e-4)" "unprognostic (1.16e-1)" "unprognostic (4.21e-3)" "unprognostic (2.28e-1)" "unprognostic (4.00e-2)" "unprognostic (1.14e-1)" "unprognostic (2.01e-1)" "unprognostic (3.64e-1)" "unprognostic (4.54e-2)" ERGIC3 "C20orf47, CGI-54, Erv46, NY-BR-84, PRO0989, SDBCAG84" ENSG00000125991 "ERGIC and golgi 3" Q9Y282 20 35542038-35557634 "Predicted membrane proteins" "ER-Golgi transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 566.5;Early spermatids: 807.9;Epididymal principal cells: 579.0;Extravillous trophoblasts: 686.3;Late spermatids: 940.6;Syncytiotrophoblasts: 705.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015242, HPA015968" Approved NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 22: Epididymis - Mixed function" "Cluster 36: Choroid plexus - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 15: Non-specific - Protein processing" 205 "HPA015242: , HPA015968: " "unprognostic (2.94e-2)" "unprognostic (1.26e-1)" "unprognostic (2.03e-1)" "unprognostic (1.30e-1)" "unprognostic (1.04e-1)" "unprognostic (1.89e-1)" "unprognostic (1.87e-1)" "unprognostic (5.23e-2)" "unprognostic (9.37e-3)" "unprognostic (1.04e-2)" "unprognostic (5.72e-2)" "potential prognostic unfavorable (1.21e-4)" "unprognostic (5.73e-2)" "validated prognostic unfavorable (1.44e-7)" "validated prognostic unfavorable (9.19e-6)" "unprognostic (6.21e-2)" "unprognostic (6.00e-2)" "unprognostic (5.06e-2)" "unprognostic (6.87e-2)" "unprognostic (1.22e-1)" "unprognostic (8.05e-3)" "unprognostic (8.65e-2)" "unprognostic (2.53e-1)" "unprognostic (1.10e-1)" "unprognostic (1.37e-1)" "unprognostic (1.90e-1)" "unprognostic (4.27e-2)" "unprognostic (3.31e-1)" "unprognostic (4.61e-1)" "unprognostic (1.32e-1)" "unprognostic (9.69e-2)" ERH DROER ENSG00000100632 "ERH mRNA splicing and mitosis factor" P84090 14 69380128-69398299 "Essential proteins, Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 649.2;Oocytes: 824.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002567 Approved Approved Nucleoplasm,Cytosol NA Yes 310000 "Cluster 30: Non-specific - DNA binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 21: Non-specific - Metabolism" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 97: Non-specific - Cellular respiration" 65 Nucleoplasm Cytosol "HPA002567: " "unprognostic (1.32e-3)" "unprognostic (7.28e-2)" "unprognostic (1.03e-2)" "unprognostic (1.68e-2)" "unprognostic (3.18e-1)" "unprognostic (4.20e-1)" "unprognostic (1.05e-1)" "unprognostic (1.02e-1)" "unprognostic (1.41e-3)" "unprognostic (1.63e-2)" "unprognostic (6.14e-3)" "unprognostic (6.58e-2)" "unprognostic (2.82e-2)" "validated prognostic unfavorable (1.40e-4)" "validated prognostic unfavorable (3.83e-4)" "potential prognostic unfavorable (8.40e-4)" "unprognostic (1.46e-1)" "unprognostic (1.51e-3)" "unprognostic (6.04e-2)" "unprognostic (5.39e-2)" "unprognostic (8.63e-2)" "unprognostic (5.22e-2)" "unprognostic (7.06e-2)" "unprognostic (5.86e-2)" "unprognostic (2.47e-1)" "unprognostic (1.46e-1)" "unprognostic (7.07e-2)" "unprognostic (1.49e-2)" "unprognostic (3.57e-1)" "unprognostic (6.51e-2)" "unprognostic (3.13e-1)" ERI1 "3'HEXO, THEX1" ENSG00000104626 "Exoribonuclease 1" Q8IV48 8 9002147-9116746 "Predicted intracellular proteins" "RNA-mediated gene silencing, rRNA processing" "Exonuclease, Hydrolase, Nuclease, RNA-binding" "Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 34.0;Ependymal cells: 31.1;Microglia: 28.8;Neutrophils: 30.7;Renal collecting duct principal cells: 30.1;Rod photoreceptor cells: 29.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033838, HPA055548, HPA056074" Uncertain Approved Vesicles,Microtubules NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 55: Non-specific - Transcription" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 102: Non-specific - Mixed function" 11 Microtubules Vesicles "CAB033838: , HPA055548: , HPA056074: " "unprognostic (1.24e-1)" "unprognostic (1.72e-1)" "unprognostic (7.54e-3)" "unprognostic (4.91e-2)" "potential prognostic favorable (2.17e-4)" "unprognostic (1.04e-1)" "unprognostic (5.55e-2)" "unprognostic (1.10e-1)" "unprognostic (2.71e-2)" "potential prognostic unfavorable (3.67e-5)" "unprognostic (3.70e-3)" "unprognostic (1.01e-1)" "unprognostic (4.07e-3)" "potential prognostic unfavorable (9.69e-4)" "unprognostic (3.08e-2)" "unprognostic (1.25e-2)" "potential prognostic unfavorable (8.89e-4)" "unprognostic (3.84e-1)" "unprognostic (1.10e-1)" "unprognostic (1.03e-1)" "unprognostic (8.33e-3)" "unprognostic (2.73e-3)" "unprognostic (2.43e-2)" "unprognostic (1.95e-1)" "unprognostic (5.74e-3)" "unprognostic (2.50e-2)" "unprognostic (5.84e-2)" "unprognostic (8.53e-2)" "unprognostic (1.72e-1)" "unprognostic (1.70e-2)" "unprognostic (4.89e-2)" ERI2 "EXOD1, KIAA1504, MGC16943, ZGRF5" ENSG00000196678 "ERI1 exoribonuclease family member 2" A8K979 16 20780193-20900349 "Predicted intracellular proteins" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 102.1;Epicardial cells: 197.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 13.8" "Lineage enriched" "Detected in many" 5 "granulocytes: 13.8" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035384, HPA035385" Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 76: Non-specific - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" Nucleoplasm "Golgi apparatus" "HPA035384: , HPA035385: " "unprognostic (1.38e-1)" "unprognostic (1.56e-1)" "unprognostic (2.41e-1)" "unprognostic (3.10e-1)" "unprognostic (1.17e-1)" "unprognostic (4.83e-3)" "unprognostic (1.53e-1)" "unprognostic (1.79e-3)" "unprognostic (2.59e-1)" "unprognostic (6.83e-2)" "potential prognostic favorable (1.25e-4)" "unprognostic (9.44e-2)" "unprognostic (2.38e-3)" "unprognostic (1.26e-1)" "unprognostic (2.23e-1)" "unprognostic (5.44e-3)" "unprognostic (2.57e-2)" "unprognostic (4.59e-2)" "unprognostic (1.70e-1)" "unprognostic (4.55e-2)" "potential prognostic unfavorable (7.01e-4)" "unprognostic (7.26e-3)" "unprognostic (2.58e-1)" "unprognostic (4.07e-2)" "potential prognostic favorable (2.20e-4)" "unprognostic (2.51e-1)" "unprognostic (9.70e-2)" "unprognostic (9.97e-2)" "unprognostic (2.96e-1)" "unprognostic (2.17e-2)" "unprognostic (2.90e-2)" ERI3 "FLJ22943, PINT1, PRNPIP" ENSG00000117419 "ERI1 exoribonuclease family member 3" O43414 1 44221070-44355260 "Predicted intracellular proteins" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 6 "Late spermatids: 1634.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027147, HPA029895" Approved Approved Nucleoplasm,Cytosol Yes No "Cluster 13: Non-specific - Mitochondria" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 51: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" "Nucleoplasm, Cytosol" "HPA027147: , HPA029895: " "unprognostic (7.57e-2)" "unprognostic (2.58e-2)" "potential prognostic unfavorable (3.15e-5)" "unprognostic (1.66e-2)" "unprognostic (3.60e-2)" "unprognostic (1.77e-1)" "unprognostic (2.03e-1)" "unprognostic (5.78e-2)" "unprognostic (1.75e-1)" "unprognostic (5.05e-2)" "unprognostic (8.15e-2)" "unprognostic (1.28e-1)" "unprognostic (2.80e-1)" "validated prognostic unfavorable (2.50e-6)" "validated prognostic unfavorable (4.94e-5)" "unprognostic (2.92e-2)" "unprognostic (4.57e-2)" "unprognostic (3.41e-1)" "unprognostic (8.44e-2)" "unprognostic (5.02e-2)" "unprognostic (4.42e-2)" "unprognostic (1.26e-1)" "unprognostic (4.20e-2)" "unprognostic (1.14e-1)" "unprognostic (3.34e-1)" "unprognostic (5.01e-2)" "unprognostic (7.93e-2)" "unprognostic (1.48e-1)" "unprognostic (1.60e-1)" "unprognostic (7.15e-2)" "unprognostic (8.98e-2)" ERICH1 ENSG00000104714 "Glutamate rich 1" Q86X53 8 614746-738106 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hematopoietic stem cells: 352.3;Platelets: 310.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003725 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 40: Non-specific - Unknown function" "Cluster 82: Dendritic cells - Antigen presentation" 4 "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "HPA003725: " "unprognostic (2.10e-2)" "unprognostic (3.59e-1)" "potential prognostic favorable (3.88e-4)" "unprognostic (1.49e-1)" "unprognostic (7.65e-2)" "unprognostic (1.89e-1)" "unprognostic (7.31e-2)" "unprognostic (2.49e-2)" "unprognostic (8.37e-2)" "unprognostic (2.54e-3)" "potential prognostic favorable (1.14e-4)" "unprognostic (4.27e-3)" "unprognostic (1.47e-3)" "unprognostic (6.35e-3)" "unprognostic (4.15e-2)" "unprognostic (1.35e-1)" "unprognostic (2.24e-1)" "unprognostic (8.35e-2)" "unprognostic (8.82e-2)" "unprognostic (3.26e-1)" "unprognostic (2.11e-1)" "unprognostic (3.35e-2)" "unprognostic (2.13e-2)" "unprognostic (2.99e-1)" "unprognostic (7.54e-3)" "unprognostic (4.62e-3)" "unprognostic (1.34e-1)" "unprognostic (1.06e-1)" "unprognostic (1.59e-1)" "unprognostic (1.14e-1)" "unprognostic (3.70e-2)" ERICH2 ENSG00000204334 "Glutamate rich 2" A1L162 2 170766878-170798977 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "choroid plexus: 45.3;testis: 155.9" "Group enriched" "Detected in many" 5 "Early spermatids: 2878.1;Late primary spermatocytes: 1068.9" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 33.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "olfactory bulb: 33.6" HPA061010 Approved "Nucleoli fibrillar center,Vesicles" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 4 "Nucleoli fibrillar center" Vesicles "HPA061010: " "unprognostic (4.90e-3)" "unprognostic (9.34e-2)" "unprognostic (3.90e-2)" "unprognostic (3.32e-1)" "unprognostic (1.00e-1)" "unprognostic (1.08e-2)" "potential prognostic unfavorable (2.51e-7)" "unprognostic (1.50e-1)" "potential prognostic unfavorable (8.41e-4)" "unprognostic (2.33e-3)" "unprognostic (2.54e-2)" "potential prognostic unfavorable (4.70e-4)" "unprognostic (1.38e-3)" "unprognostic (2.92e-1)" "unprognostic (2.77e-2)" "unprognostic (5.93e-2)" "unprognostic (2.48e-1)" "unprognostic (7.42e-2)" "unprognostic (1.81e-2)" "unprognostic (1.60e-2)" "unprognostic (1.74e-1)" "unprognostic (1.94e-3)" "unprognostic (2.61e-3)" "unprognostic (1.16e-1)" "unprognostic (3.82e-2)" "unprognostic (5.33e-2)" "unprognostic (4.65e-2)" ERICH3 "C1orf173, DKFZp547I048, RP11-653A5.1" ENSG00000178965 "Glutamate rich 3" Q5RHP9 1 74568117-74673792 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.4;fallopian tube: 16.3;testis: 22.6" "Cell type enhanced" "Detected in many" "Early spermatids: 320.0;Endometrial ciliated cells: 283.1;Ependymal cells: 236.5;Epididymal efferent duct ciliated cells: 296.7;Fallopian tube ciliated cells: 554.7;Lactotrophs: 141.6;Late primary spermatocytes: 252.8;Late spermatids: 532.9;Respiratory ciliated cells: 984.9;Thyrotrophs: 140.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 2.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Rhabdoid: 4.0" "Colon - Colon enteroendocrine cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028655, HPA072916" Approved Uncertain "Nuclear membrane,Nucleoli,Endoplasmic reticulum,Primary cilium" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 51: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 107: Ciliated cells - Cilia assembly & function" "Nuclear membrane, Endoplasmic reticulum" "Nucleoli, Primary cilium" "HPA028655: , HPA072916: " "unprognostic (1.20e-1)" "unprognostic (7.07e-3)" "unprognostic (3.68e-3)" "unprognostic (7.73e-2)" ERICH4 "C19orf69, LOC100170765" ENSG00000204978 "Glutamate rich 4" A6NGS2 19 41443156-41444765 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "intestine: 40.0;kidney: 15.4" "Cell type enriched" "Detected in some" 14 "Enterocytes: 190.2" "Cell type enriched" "Detected in single" 31 "endothelial cell: 5.9" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Minor Salivary Gland - Fibroblasts, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA042632, HPA048484" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 47: Endothelial cells - Vasculature" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 1: Enterocytes - Absorption and Digestion" 2 Nucleoplasm Cytosol "HPA042632: , HPA048484: " "unprognostic (2.45e-1)" ERICH5 "C8orf47, FLJ39553" ENSG00000177459 "Glutamate rich 5" Q6P6B1 8 98064522-98093610 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 32.2" "Cell type enhanced" "Detected in many" "Cholangiocytes: 108.7;Fallopian tube ciliated cells: 65.2;Ocular epithelial cells: 350.1;Pancreatic duct cells: 92.9;Respiratory ciliated cells: 91.6" "Cell type enhanced" "Detected in many" "midbrain-derived inhibitory: 9.3" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 42.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "myeloid DC: 2.2" "Lineage enriched" "Detected in single" 11 "dendritic cells: 2.2" "Cancer enhanced" "Detected in many" "liver cancer: 10.6" "Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells" "Not detected" "Not detected" "HPA025070, HPA025293, HPA027233" Enhanced Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 8: Pancreas - Proteolysis" "Cluster 1: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 100: Stratified epithelial cells - Barrier functions" 4 "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA025070: , HPA025293: , HPA027233: " "potential prognostic favorable (4.33e-4)" "unprognostic (2.85e-1)" "unprognostic (9.93e-2)" "unprognostic (1.27e-1)" "validated prognostic favorable (1.71e-10)" "validated prognostic favorable (8.87e-6)" "unprognostic (1.33e-1)" "unprognostic (1.68e-1)" "unprognostic (3.34e-1)" "unprognostic (1.21e-1)" "unprognostic (9.34e-2)" "unprognostic (1.26e-1)" "unprognostic (2.41e-1)" "unprognostic (1.01e-1)" "unprognostic (1.09e-1)" "unprognostic (9.18e-2)" "unprognostic (4.54e-1)" "unprognostic (4.26e-1)" "unprognostic (1.61e-2)" "unprognostic (8.17e-2)" "unprognostic (1.74e-1)" "unprognostic (3.80e-1)" "unprognostic (1.02e-2)" ERICH6 "C3orf44, ERICH6A, FAM194A, MGC39662" ENSG00000163645 "Glutamate rich 6" Q7L0X2 3 150659885-150703971 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "testis: 27.8" "Group enriched" "Detected in many" 6 "Early spermatids: 131.8;Late primary spermatocytes: 142.0;Late spermatids: 128.5" "Cell type enhanced" "Detected in many" "ependymal cell: 22.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA048373 Enhanced NA NA "Cluster 24: Non-specific - Transcription" "Cluster 57: Testis - Spermatogenesis" "Cluster 33: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" "HPA048373: " "unprognostic (1.04e-2)" "unprognostic (1.18e-2)" "unprognostic (2.32e-1)" "unprognostic (2.23e-1)" "unprognostic (8.89e-2)" ERICH6B "FAM194B, FLJ32682" ENSG00000165837 "Glutamate rich 6B" Q5W0A0 13 45534522-45615739 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 9 "testis: 1.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 37.0;Early spermatids: 41.9;Ependymal cells: 12.4;Epicardial cells: 25.0;Late primary spermatocytes: 52.2;Late spermatids: 27.9" "Cell type enhanced" "Detected in many" "ependymal cell: 14.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" HPA043559 Uncertain NA NA "Cluster 47: Testis - Mixed function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "HPA043559: " ERLEC1 "C2orf30, CL25084, ERLECTIN, XTP3-B, XTP3TPB" ENSG00000068912 "Endoplasmic reticulum lectin 1" Q96DZ1 2 53787009-53833038 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epididymal principal cells: 333.6;Plasma cells: 464.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031501, HPA031502, HPA031503" Enhanced "Intracellular and membrane" "No annotated function" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 22: Epididymis - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 44: Plasma cells - Antibody production & secretion" 52 "HPA031501: , HPA031502: , HPA031503: " "unprognostic (3.21e-2)" "unprognostic (3.27e-3)" "unprognostic (1.58e-1)" "unprognostic (1.31e-3)" "unprognostic (1.97e-1)" "unprognostic (4.40e-2)" "unprognostic (1.08e-2)" "unprognostic (2.90e-3)" "unprognostic (9.94e-2)" "unprognostic (4.51e-2)" "potential prognostic favorable (4.94e-5)" "unprognostic (3.62e-1)" "unprognostic (1.37e-2)" "unprognostic (5.47e-3)" "unprognostic (2.22e-3)" "unprognostic (2.08e-1)" "unprognostic (1.68e-1)" "unprognostic (4.90e-2)" "unprognostic (1.41e-1)" "unprognostic (2.83e-1)" "potential prognostic unfavorable (1.24e-4)" "unprognostic (1.67e-1)" "unprognostic (1.14e-2)" "unprognostic (3.06e-1)" "unprognostic (3.71e-1)" "unprognostic (1.98e-1)" "unprognostic (8.73e-2)" "unprognostic (1.45e-1)" "unprognostic (3.65e-2)" "unprognostic (2.14e-2)" "unprognostic (1.13e-1)" ERLIN1 "C10orf69, Erlin-1, KE04, SPFH1, SPG62" ENSG00000107566 "ER lipid raft associated 1" O75477 10 100150094-100186033 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 106.7" "Cell type enhanced" "Detected in many" "Monocyte progenitors: 142.2;Neutrophil progenitors: 215.5;Neutrophils: 150.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Urothelial cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" HPA011252 Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 31: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 56 "Endoplasmic reticulum" "HPA011252: " "unprognostic (3.70e-2)" "unprognostic (8.10e-2)" "unprognostic (1.95e-1)" "unprognostic (1.48e-2)" "unprognostic (1.94e-1)" "unprognostic (8.62e-2)" "unprognostic (1.90e-1)" "unprognostic (1.41e-2)" "unprognostic (7.46e-2)" "unprognostic (3.07e-2)" "potential prognostic favorable (2.35e-5)" "unprognostic (1.91e-1)" "unprognostic (7.51e-3)" "unprognostic (8.14e-2)" "unprognostic (3.98e-2)" "unprognostic (1.10e-3)" "unprognostic (2.64e-2)" "unprognostic (2.05e-1)" "unprognostic (1.06e-1)" "unprognostic (5.62e-2)" "unprognostic (1.18e-2)" "potential prognostic unfavorable (3.49e-4)" "unprognostic (1.12e-1)" "unprognostic (6.01e-2)" "unprognostic (6.17e-3)" "unprognostic (2.74e-1)" "unprognostic (2.12e-1)" "unprognostic (2.14e-2)" "unprognostic (3.10e-1)" "unprognostic (1.79e-1)" "unprognostic (5.33e-2)" ERLIN2 "C8orf2, Erlin-2, NET32, SPFH2, SPG18" ENSG00000147475 "ER lipid raft associated 2" O94905 8 37736601-37758422 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cell type enhanced" "Detected in all" "ependymal cell: 66.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002025, CAB014894" Supported Supported "Endoplasmic reticulum" "Intracellular and membrane" Other NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 70 "Endoplasmic reticulum" "CAB014894: , HPA002025: " "unprognostic (1.09e-2)" "unprognostic (1.95e-3)" "unprognostic (4.75e-1)" "unprognostic (1.56e-2)" "unprognostic (1.24e-2)" "unprognostic (7.68e-3)" "unprognostic (3.47e-3)" "unprognostic (6.10e-2)" "unprognostic (3.27e-2)" "potential prognostic unfavorable (3.31e-4)" "potential prognostic favorable (2.43e-8)" "unprognostic (6.03e-3)" "unprognostic (1.20e-2)" "unprognostic (6.63e-2)" "unprognostic (1.82e-1)" "unprognostic (1.68e-1)" "unprognostic (3.29e-1)" "unprognostic (4.23e-2)" "unprognostic (5.89e-3)" "unprognostic (3.58e-1)" "unprognostic (1.38e-2)" "unprognostic (3.20e-3)" "unprognostic (4.00e-2)" "unprognostic (8.52e-3)" "unprognostic (1.58e-2)" "unprognostic (5.72e-2)" "unprognostic (6.92e-2)" "unprognostic (1.47e-1)" "unprognostic (2.22e-1)" "unprognostic (2.77e-1)" "unprognostic (7.00e-2)" ERMAP "BTN5, RD, SC" ENSG00000164010 "Erythroblast membrane associated protein (Scianna blood group)" Q96PL5 1 42817122-42844991 "Blood group antigen proteins, Predicted intracellular proteins, Predicted membrane proteins" "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 99.3;Late spermatids: 65.7;Microglia: 85.2" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 104.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" "HPA042573, HPA054672" Uncertain Approved "Golgi apparatus,Cytosol" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 22: Epididymis - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 7 "Golgi apparatus" Cytosol "HPA042573: , HPA054672: " "unprognostic (1.47e-2)" "unprognostic (1.65e-1)" "unprognostic (9.04e-2)" "unprognostic (3.19e-3)" "unprognostic (1.01e-1)" "unprognostic (6.85e-2)" "unprognostic (5.35e-2)" "unprognostic (3.12e-1)" "unprognostic (1.29e-2)" "unprognostic (1.20e-1)" "potential prognostic favorable (3.62e-7)" "unprognostic (9.60e-2)" "unprognostic (2.46e-2)" "unprognostic (5.34e-2)" "potential prognostic favorable (2.40e-4)" "unprognostic (5.67e-2)" "unprognostic (1.04e-1)" "unprognostic (3.20e-2)" "unprognostic (2.49e-3)" "unprognostic (1.39e-1)" "unprognostic (2.36e-1)" "unprognostic (2.49e-1)" "unprognostic (5.77e-2)" "unprognostic (1.32e-1)" "unprognostic (1.78e-2)" "unprognostic (3.87e-1)" "unprognostic (1.72e-1)" "unprognostic (3.70e-2)" "unprognostic (1.54e-1)" "unprognostic (1.97e-1)" "unprognostic (3.43e-2)" ERMARD "C6orf70, dJ266L20.3, FLJ11152" ENSG00000130023 "ER membrane associated RNA degradation" Q5T6L9 6 169751622-169781600 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 37.8;Early spermatids: 41.3;Ependymal cells: 40.2;Late primary spermatocytes: 52.1;Late spermatids: 65.0;Oocytes: 170.4;Podocytes: 46.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041741 Approved Approved Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 67: Testis - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 41: Oocytes - Oogenesis" Cytosol "HPA041741: " "unprognostic (4.51e-3)" "unprognostic (3.74e-3)" "unprognostic (7.90e-2)" "unprognostic (1.08e-2)" "unprognostic (4.04e-1)" "unprognostic (2.35e-1)" "unprognostic (2.89e-1)" "unprognostic (6.05e-2)" "unprognostic (6.13e-2)" "unprognostic (7.83e-3)" "unprognostic (3.61e-2)" "unprognostic (4.84e-2)" "unprognostic (1.75e-1)" "unprognostic (9.13e-2)" "unprognostic (2.55e-2)" "unprognostic (6.31e-2)" "unprognostic (4.75e-3)" "unprognostic (1.47e-2)" "unprognostic (3.09e-2)" "potential prognostic favorable (1.79e-4)" "unprognostic (1.38e-2)" "unprognostic (3.80e-1)" "unprognostic (2.26e-2)" "unprognostic (9.82e-3)" "unprognostic (2.93e-1)" "unprognostic (1.79e-1)" "unprognostic (1.12e-1)" "unprognostic (2.71e-1)" "unprognostic (2.91e-2)" ERMN "ERMIN, JN, KIAA1189" ENSG00000136541 Ermin Q8TAM6 2 157318631-157327713 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "brain: 596.2" "Group enriched" "Detected in some" 28 "Oligodendrocytes: 273.5;Retinal pigment epithelial cells: 716.2" "Cell type enriched" "Detected in many" 6 "oligodendrocyte: 407.8" "Cancer enriched" "Detected in many" 5 "Glioblastoma Multiforme (TCGA): 19.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in some" "Myeloma: 6.3" "Kidney - T-cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038295, HPA038296" Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" 1 "Plasma membrane" Cytosol "HPA038295: , HPA038296: " "unprognostic (9.27e-2)" "unprognostic (2.74e-2)" "unprognostic (4.79e-2)" "unprognostic (1.25e-1)" "unprognostic (2.02e-1)" "unprognostic (1.63e-1)" "unprognostic (4.96e-3)" "unprognostic (1.03e-1)" "unprognostic (2.29e-1)" "unprognostic (2.81e-2)" "unprognostic (2.01e-1)" "unprognostic (1.64e-3)" "unprognostic (2.89e-2)" "unprognostic (1.66e-1)" "unprognostic (9.28e-2)" ERMP1 "FLJ23309, FXNA, KIAA1815" ENSG00000099219 "Endoplasmic reticulum metallopeptidase 1" Q7Z2K6 9 5749832-5879537 "Enzymes, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 20.9" "Cell type enhanced" "Detected in many" "Epicardial cells: 486.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 1.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary gland ductal cells, Skin - Mitotic cells (Skin), Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055582 Approved NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 56 "HPA055582: " "unprognostic (4.36e-1)" "unprognostic (5.91e-2)" "unprognostic (6.09e-2)" "unprognostic (6.47e-3)" "unprognostic (9.56e-2)" "unprognostic (3.94e-1)" "unprognostic (3.45e-1)" "unprognostic (1.09e-1)" "unprognostic (2.05e-1)" "unprognostic (1.98e-1)" "potential prognostic favorable (1.09e-8)" "unprognostic (1.98e-3)" "unprognostic (1.86e-1)" "unprognostic (1.93e-1)" "unprognostic (2.70e-2)" "unprognostic (2.75e-1)" "unprognostic (6.91e-2)" "unprognostic (9.02e-2)" "unprognostic (8.48e-2)" "unprognostic (3.30e-2)" "unprognostic (5.43e-2)" "unprognostic (1.40e-2)" "unprognostic (1.87e-1)" "unprognostic (2.30e-2)" "unprognostic (7.43e-3)" "unprognostic (7.05e-2)" "unprognostic (4.29e-2)" "unprognostic (1.51e-1)" "unprognostic (3.11e-1)" "unprognostic (5.47e-2)" "unprognostic (8.17e-3)" ERN1 "IRE1, IRE1P" ENSG00000178607 "Endoplasmic reticulum to nucleus signaling 1" O75460 17 64039080-64130819 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Transcription, Transcription regulation, Unfolded protein response" "Hydrolase, Kinase, Multifunctional enzyme, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 63.0" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 522.6;Neutrophils: 710.5;pDCs: 926.1;Plasma cells: 519.1" "Cell type enriched" "Detected in all" 4 "leukocyte: 165.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 17.9" "Group enriched" "Detected in many" 5 "dendritic cells: 7.7;granulocytes: 17.9;T-cells: 9.0" "Cancer enriched" "Detected in all" 8 "Myeloma: 91.4" "Adrenal gland - Adrenal cortex cells, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009495, HPA027730" Supported NA Yes "Cluster 41: Basophils - Unknown function" "Cluster 8: Pancreas - Proteolysis" "Cluster 48: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 22 "CAB009495: , HPA027730: " "unprognostic (5.57e-2)" "unprognostic (2.66e-1)" "unprognostic (3.23e-1)" "unprognostic (2.48e-3)" "unprognostic (1.54e-1)" "unprognostic (2.08e-3)" "unprognostic (2.24e-1)" "unprognostic (1.21e-3)" "unprognostic (2.54e-2)" "unprognostic (2.88e-3)" "unprognostic (2.21e-2)" "unprognostic (1.38e-2)" "unprognostic (1.16e-1)" "unprognostic (1.90e-1)" "unprognostic (1.45e-1)" "unprognostic (1.80e-1)" "unprognostic (8.41e-2)" "unprognostic (6.07e-3)" "unprognostic (1.54e-1)" "unprognostic (1.28e-1)" "unprognostic (1.88e-3)" "unprognostic (2.49e-1)" "unprognostic (2.34e-3)" "unprognostic (9.60e-2)" "unprognostic (2.65e-2)" "unprognostic (1.09e-3)" "unprognostic (5.45e-2)" "unprognostic (3.46e-1)" "unprognostic (4.14e-1)" "unprognostic (2.68e-2)" "unprognostic (1.76e-1)" ERN2 IRE1b ENSG00000134398 "Endoplasmic reticulum to nucleus signaling 2" Q76MJ5 16 23690310-23713226 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Transcription, Transcription regulation" "Hydrolase, Kinase, Multifunctional enzyme, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "cervix: 18.3;gallbladder: 15.9;intestine: 27.7;salivary gland: 22.5;stomach 1: 49.0" "Cell type enhanced" "Detected in some" "Colonocytes: 109.3;Conjunctival goblet cells: 107.8;Enteric stem cells: 68.7;Enteric transient amplifying cells: 66.0;Foveolar cells: 164.5;Goblet cells: 269.7;Mucous neck cells: 93.0;Papillary tip epithelial cells: 65.3;Prostatic club cells: 153.3;Prostatic hillock cells: 118.4;Respiratory basal cells: 61.9;Respiratory deuterosomal cells: 71.5;Respiratory secretory cells: 178.5;Submucosal glandular cells: 51.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 28.1;Pancreatic Adenocarcinoma (TCGA): 32.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Bile duct cancer: 13.3;colorectal cancer: 19.5;Gallbladder cancer: 8.9;Gastric cancer: 16.2;pancreatic cancer: 8.7" "Breast - Adipocytes (Breast), Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Ductal cells, Pituitary gland - Gonadotropes, Prostate - Urothelial cells, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA076875 Approved Approved "Endoplasmic reticulum,Cytosol" "Intracellular and membrane" Transcription NA NA "Cluster 17: Intestine - Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 70: Intestinal goblet cells - Mucin production" "Endoplasmic reticulum, Cytosol" "HPA076875: " "unprognostic (6.86e-2)" "unprognostic (1.78e-2)" "unprognostic (7.65e-2)" "unprognostic (1.58e-2)" "potential prognostic unfavorable (1.09e-8)" "unprognostic (1.24e-1)" "unprognostic (2.08e-3)" "unprognostic (8.37e-2)" "unprognostic (2.16e-1)" "unprognostic (7.69e-2)" "unprognostic (1.56e-2)" "unprognostic (1.37e-1)" "unprognostic (2.69e-3)" "unprognostic (9.01e-2)" "unprognostic (6.28e-3)" ERO1A "ERO1-alpha, Ero1alpha, ERO1L" ENSG00000197930 "Endoplasmic reticulum oxidoreductase 1 alpha" Q96HE7 14 52639915-52695900 "Plasma proteins, Predicted intracellular proteins, Transporters" "Apoptosis, Electron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 169.0" "Cell type enriched" "Detected in many" 20 "Esophageal apical cells: 10958.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026653, HPA030053, CAB034294" Enhanced "Intracellular and membrane" Transport NA NA 30000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 84: Apical squamous epithelium - Cornification" 18 "CAB034294: , HPA026653: , HPA030053: " "unprognostic (7.01e-2)" "unprognostic (6.30e-2)" "unprognostic (1.14e-3)" "unprognostic (1.20e-1)" "unprognostic (7.19e-2)" "unprognostic (6.78e-3)" "unprognostic (4.92e-2)" "unprognostic (6.19e-2)" "unprognostic (3.18e-3)" "potential prognostic unfavorable (8.64e-4)" "unprognostic (1.78e-1)" "unprognostic (2.56e-3)" "potential prognostic unfavorable (1.95e-4)" "validated prognostic unfavorable (1.22e-8)" "validated prognostic unfavorable (1.26e-4)" "unprognostic (2.60e-2)" "unprognostic (6.14e-2)" "unprognostic (7.19e-2)" "unprognostic (1.12e-1)" "potential prognostic unfavorable (6.78e-4)" "unprognostic (1.27e-3)" "unprognostic (1.85e-1)" "unprognostic (7.20e-2)" "unprognostic (1.41e-2)" "unprognostic (6.47e-2)" "unprognostic (1.93e-1)" "unprognostic (1.65e-1)" "unprognostic (3.34e-2)" "unprognostic (1.74e-2)" ERO1B "ERO1-L(beta), Ero1beta, ERO1LB" ENSG00000086619 "Endoplasmic reticulum oxidoreductase 1 beta" Q86YB8 1 236214681-236282019 "Predicted intracellular proteins" "Electron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "pancreas: 172.5" "Cell type enhanced" "Detected in all" "Gastric chief cells: 323.2;Pancreatic acinar cells: 430.8;Pancreatic islet cells: 742.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Stomach - Chief cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028085 Enhanced "Intracellular and membrane" Transport NA NA "Cluster 41: Basophils - Unknown function" "Cluster 8: Pancreas - Proteolysis" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 7 "HPA028085: " "unprognostic (1.44e-2)" "unprognostic (5.68e-2)" "unprognostic (3.69e-2)" "unprognostic (1.51e-1)" "unprognostic (8.02e-2)" "unprognostic (2.13e-1)" "unprognostic (1.58e-1)" "unprognostic (2.19e-1)" "unprognostic (8.43e-2)" "potential prognostic favorable (3.53e-7)" "unprognostic (1.40e-2)" "unprognostic (4.35e-2)" "unprognostic (3.90e-2)" "validated prognostic favorable (1.18e-4)" "validated prognostic favorable (6.11e-4)" "unprognostic (2.84e-1)" "unprognostic (1.28e-1)" "unprognostic (2.76e-2)" "unprognostic (2.11e-1)" "unprognostic (3.67e-2)" "unprognostic (5.58e-3)" "unprognostic (1.52e-1)" "unprognostic (3.51e-1)" "unprognostic (3.23e-2)" "unprognostic (9.99e-2)" "unprognostic (2.36e-1)" "unprognostic (6.99e-2)" "unprognostic (3.76e-3)" "unprognostic (5.25e-2)" ERP27 "C12orf46, FLJ32115, PDIA8" ENSG00000139055 "Endoplasmic reticulum protein 27" Q96DN0 12 14914039-14938537 "Predicted intracellular proteins" "Unfolded protein response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 23 "pancreas: 1699.9" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 51.3;Epididymal clear cells: 179.6;Fallopian secretory cells: 123.8;Fallopian tube ciliated cells: 159.6;Pancreatic acinar cells: 317.9;Pancreatic duct cells: 50.9;Prostatic club cells: 44.8;Transitional alveolar cells: 55.0;Urothelial cells: 46.1" "Group enriched" "Detected in some" 10 "central nervous system macrophage: 10.2;leukocyte: 20.7" "Cancer enriched" "Detected in all" 8 "Kidney Chromophobe (TCGA): 339.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Bile duct cancer: 23.7" "Pancreas - Exocrine glandular cells" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA039636, HPA052851" Enhanced "Intracellular and membrane" Other NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 8: Pancreas - Proteolysis" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 9: T-cells - Adaptive immunity: Regulation" 20 "HPA039636: , HPA052851: " "unprognostic (2.95e-1)" "unprognostic (8.38e-2)" "unprognostic (2.70e-2)" "unprognostic (1.82e-1)" "unprognostic (2.51e-1)" "unprognostic (9.41e-3)" "unprognostic (1.68e-1)" "unprognostic (1.50e-1)" "unprognostic (4.95e-2)" "unprognostic (8.45e-2)" "unprognostic (6.45e-2)" "unprognostic (1.80e-2)" "unprognostic (4.31e-2)" "unprognostic (2.00e-1)" "unprognostic (1.20e-1)" "unprognostic (1.84e-1)" "unprognostic (2.57e-2)" "unprognostic (8.73e-2)" "unprognostic (1.29e-1)" "unprognostic (1.18e-1)" "unprognostic (1.38e-1)" "unprognostic (1.81e-2)" "unprognostic (1.25e-3)" "unprognostic (6.84e-2)" "unprognostic (1.35e-1)" "unprognostic (5.59e-2)" "unprognostic (4.31e-2)" "unprognostic (1.22e-2)" "unprognostic (2.59e-1)" "unprognostic (2.33e-2)" "unprognostic (7.97e-2)" ERP29 "C12orf8, ERp28, ERp31, PDI-DB, PDIA9" ENSG00000089248 "Endoplasmic reticulum protein 29" P30040 12 112013348-112023449 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 592.8;Esophageal apical cells: 595.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Skin - Keratinocyte (other), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039363, HPA039456" Enhanced Uncertain Nucleoplasm,Microtubules "Intracellular and membrane" "No annotated function" NA NA 1400000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 70: Non-specific - Protein processing" "Cluster 44: Non-specific - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 26 Microtubules Nucleoplasm "HPA039363: , HPA039456: " "unprognostic (1.24e-2)" "unprognostic (2.44e-1)" "unprognostic (4.53e-2)" "unprognostic (5.04e-2)" "unprognostic (2.55e-1)" "unprognostic (3.13e-1)" "unprognostic (7.49e-3)" "unprognostic (1.67e-2)" "unprognostic (2.02e-1)" "potential prognostic unfavorable (5.16e-4)" "unprognostic (6.77e-3)" "unprognostic (2.21e-3)" "unprognostic (1.55e-1)" "validated prognostic unfavorable (2.13e-5)" "validated prognostic unfavorable (9.44e-5)" "unprognostic (1.94e-1)" "unprognostic (3.23e-1)" "unprognostic (1.30e-1)" "unprognostic (3.68e-2)" "unprognostic (3.84e-2)" "unprognostic (6.13e-2)" "unprognostic (2.94e-2)" "unprognostic (3.63e-2)" "unprognostic (1.34e-1)" "unprognostic (8.83e-2)" "unprognostic (1.68e-1)" "unprognostic (8.47e-2)" "unprognostic (1.37e-2)" "unprognostic (2.61e-1)" "unprognostic (1.33e-3)" "unprognostic (6.90e-3)" ERP44 "KIAA0573, PDIA10, TXNDC4" ENSG00000023318 "Endoplasmic reticulum protein 44" Q9BS26 9 99979185-100099052 "Plasma proteins, Predicted intracellular proteins" "Stress response" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001318 Supported "Intracellular and membrane" Other NA NA 6700000 "Cluster 40: Monocytes - Innate immune response" "Cluster 22: Epididymis - Mixed function" "Cluster 2: Neurons - Nucleosome" "Cluster 63: Non-specific - Protein processing" "Cluster 8: Non-specific - Secretory pathway" 28 "HPA001318: " "unprognostic (2.23e-1)" "unprognostic (4.33e-3)" "unprognostic (1.94e-1)" "unprognostic (5.26e-2)" "unprognostic (1.60e-1)" "unprognostic (2.90e-2)" "unprognostic (2.84e-1)" "unprognostic (1.95e-1)" "potential prognostic unfavorable (3.58e-4)" "unprognostic (9.99e-3)" "potential prognostic favorable (2.94e-6)" "unprognostic (4.94e-2)" "unprognostic (9.51e-3)" "unprognostic (1.89e-1)" "unprognostic (1.56e-1)" "unprognostic (1.36e-1)" "unprognostic (3.71e-1)" "unprognostic (2.55e-3)" "unprognostic (2.53e-1)" "unprognostic (2.06e-1)" "unprognostic (5.59e-2)" "unprognostic (4.91e-2)" "unprognostic (1.49e-1)" "unprognostic (1.64e-1)" "unprognostic (2.65e-1)" "unprognostic (2.89e-3)" "unprognostic (1.27e-1)" "unprognostic (1.87e-1)" "unprognostic (8.36e-2)" "unprognostic (1.80e-1)" "unprognostic (7.69e-3)" ERRFI1 "GENE-33, MIG-6, RALT" ENSG00000116285 "ERBB receptor feedback inhibitor 1" Q9UJM3 1 8004404-8026309 "Predicted intracellular proteins" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 695.4;pancreas: 640.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 800.4;Basal keratinocytes: 1275.1;Epididymal basal cells: 806.0;Hepatocytes: 1316.1;Pancreatic acinar cells: 759.6;Proximal tubule cells: 984.2;Thymic myoid cells: 985.7" "Cell type enhanced" "Detected in all" "vascular associated smooth muscle cell: 123.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "non-classical monocyte: 2.0" "Lineage enriched" "Detected in single" 5 "monocytes: 2.0" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027206, HPA076543" Enhanced Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 70: Non-specific - Protein processing" "Cluster 25: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 26: Keratinocytes - Keratinization" 28 Cytosol "HPA027206: , HPA076543: " "unprognostic (1.77e-2)" "unprognostic (1.21e-3)" "unprognostic (1.07e-1)" "unprognostic (1.49e-3)" "unprognostic (6.10e-2)" "unprognostic (1.41e-2)" "unprognostic (4.14e-3)" "potential prognostic unfavorable (1.20e-4)" "unprognostic (2.13e-3)" "unprognostic (3.06e-1)" "unprognostic (5.39e-3)" "unprognostic (2.67e-1)" "unprognostic (7.77e-2)" "unprognostic (1.90e-2)" "unprognostic (2.16e-1)" "potential prognostic unfavorable (1.56e-4)" "unprognostic (2.78e-3)" "unprognostic (2.97e-2)" "unprognostic (1.15e-1)" "unprognostic (2.99e-2)" "unprognostic (1.13e-1)" "unprognostic (6.92e-2)" "potential prognostic unfavorable (8.05e-5)" "unprognostic (4.98e-1)" "unprognostic (2.83e-1)" "potential prognostic favorable (2.69e-4)" "unprognostic (7.00e-2)" "unprognostic (1.37e-3)" "unprognostic (2.99e-1)" "unprognostic (3.30e-2)" "unprognostic (1.12e-1)" ERV3-1 "envR, ERV-R, ERV3, H-PLK, HERV-R" ENSG00000213462 "Endogenous retrovirus group 3 member 1, envelope" Q14264 7 64990356-65006743 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 7 "Platelets: 109.9" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 1.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 7.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Skin - Sebaceous gland cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "HPA017209, HPA046508" Enhanced Approved "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 47: Platelets - Hemostasis" Vesicles "Golgi apparatus, Cytosol" "HPA017209: , HPA046508: " "unprognostic (4.85e-2)" "unprognostic (1.27e-1)" "unprognostic (1.29e-2)" "unprognostic (5.39e-2)" "unprognostic (1.21e-1)" "unprognostic (2.07e-1)" "unprognostic (1.04e-1)" "unprognostic (1.47e-1)" "unprognostic (4.50e-2)" "unprognostic (1.40e-1)" "unprognostic (2.41e-2)" "unprognostic (2.18e-1)" "unprognostic (4.44e-2)" "unprognostic (1.80e-1)" "unprognostic (1.73e-1)" "unprognostic (4.01e-1)" "unprognostic (2.25e-1)" "unprognostic (3.62e-1)" "unprognostic (2.48e-2)" "unprognostic (1.47e-2)" "unprognostic (1.10e-1)" "unprognostic (8.37e-2)" "unprognostic (1.54e-1)" "unprognostic (7.23e-2)" "unprognostic (3.21e-2)" "unprognostic (1.44e-1)" "unprognostic (9.97e-2)" "unprognostic (4.07e-1)" "unprognostic (5.56e-2)" ERVFRD-1 "envFRD, ERVFRDE1, HERV-FRD, HERV-W/FRD, syncytin-2" ENSG00000244476 "Endogenous retrovirus group FRD member 1, envelope" P60508 6 11102489-11111725 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "placenta: 34.8" "Cell type enriched" "Detected in some" 30 "Syncytiotrophoblasts: 906.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Kidney Chromophobe (TCGA): 2.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 53 "testis cancer: 35.7" "Adipose subcutaneous - Mast cells, Colon - Mast cells, Minor Salivary Gland - Mast cells, Prostate - Fibroblasts" HPA011812 Uncertain "Nucleoplasm,Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 15: Non-specific - Transcription" "Cluster 34: Testis cancer - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 21 "Plasma membrane, Actin filaments" "Nucleoplasm, Cytosol" "HPA011812: " "unprognostic (1.12e-1)" "unprognostic (3.42e-1)" "unprognostic (2.17e-1)" ERVH48-1 "C21orf105, NDUFV3-AS1, SUPYN" ENSG00000233056 "Endogenous retrovirus group 48 member 1" M5A8F1 21 42916803-42925630 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 99 "placenta: 143.9" "Group enriched" "Detected in some" 7 "Cytotrophoblasts: 164.7;Extravillous trophoblasts: 370.5;Migrating cytotrophoblasts: 206.7;Syncytiotrophoblasts: 95.8" "Low cell type specificity" "Detected in some" "Cancer enriched" "Detected in some" 15 "Testicular Germ Cell Tumor (TCGA): 134.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "neutrophil: 7.8" "Lineage enriched" "Detected in single" 12 "granulocytes: 7.8" "Cancer enriched" "Detected in many" 5 "testis cancer: 41.3" "Prostate - Prostate glandular cells" "Secreted in female reproductive system" "No annotated function" NA NA 24000 "Cluster 21: Neutrophils - Unknown function" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 34: Testis cancer - Unknown function" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" "unprognostic (1.39e-1)" "unprognostic (7.93e-2)" "unprognostic (8.36e-2)" "unprognostic (1.36e-2)" "unprognostic (9.51e-2)" "unprognostic (8.89e-2)" "unprognostic (3.07e-1)" ERVK3-1 HERV-K(HML6-1) ENSG00000142396 "Endogenous retrovirus group K3 member 1" 19 58305374-58316812 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 73.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 15: Non-specific - Protein processing" "unprognostic (5.28e-3)" "unprognostic (2.74e-1)" "unprognostic (3.33e-1)" "unprognostic (3.17e-2)" "unprognostic (2.84e-1)" "unprognostic (8.19e-2)" "unprognostic (9.13e-2)" "unprognostic (1.71e-2)" "unprognostic (2.03e-3)" "unprognostic (1.04e-2)" "unprognostic (2.22e-2)" "unprognostic (9.28e-2)" "potential prognostic unfavorable (1.78e-6)" "unprognostic (9.32e-3)" "unprognostic (2.45e-1)" "unprognostic (3.25e-2)" "unprognostic (2.16e-1)" "unprognostic (2.52e-2)" "unprognostic (1.77e-2)" "unprognostic (1.28e-1)" "unprognostic (5.64e-2)" "unprognostic (5.38e-3)" "unprognostic (1.51e-1)" "unprognostic (9.37e-2)" "unprognostic (2.36e-2)" "unprognostic (3.33e-1)" "unprognostic (3.85e-2)" "unprognostic (2.15e-1)" "unprognostic (2.87e-1)" ERVMER34-1 envMER34 ENSG00000226887 "Endogenous retrovirus group MER34 member 1, envelope" Q9H9K5 4 52722618-52751586 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "parathyroid gland: 12.1;placenta: 10.2" "Group enriched" "Detected in many" 7 "Cytotrophoblasts: 101.1;Extravillous trophoblasts: 114.5;Migrating cytotrophoblasts: 143.1" "Cell type enriched" "Detected in some" 4 "endothelial cell: 8.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes" "HPA011423, HPA024053" Approved Approved Nucleoplasm,Cytosol "Secreted to blood" "No annotated function" NA NA 520000 "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 8 Nucleoplasm Cytosol "HPA011423: , HPA024053: " "unprognostic (5.58e-2)" "unprognostic (3.45e-3)" "unprognostic (1.59e-1)" "unprognostic (8.50e-2)" "unprognostic (7.51e-3)" "unprognostic (4.15e-2)" "unprognostic (1.44e-3)" "unprognostic (5.14e-2)" "unprognostic (1.11e-2)" "unprognostic (2.85e-2)" "unprognostic (3.79e-2)" "unprognostic (3.73e-3)" "unprognostic (4.41e-2)" "unprognostic (1.10e-2)" "unprognostic (3.08e-1)" "unprognostic (1.53e-2)" "unprognostic (8.05e-3)" "unprognostic (1.96e-2)" "unprognostic (1.42e-2)" "unprognostic (1.09e-1)" "unprognostic (1.59e-2)" ERVV-1 "ENVV1, FLJ32214, HERV-V1" ENSG00000269526 "Endogenous retrovirus group V member 1, envelope" B6SEH8 19 53013921-53016123 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 15 "placenta: 15.1" "Cell type enriched" "Detected in some" 45 "Syncytiotrophoblasts: 385.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder Urothelial Carcinoma (TCGA): 1.7;Kidney Renal Papillary Cell Carcinoma (TCGA): 2.2" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 11 "testis cancer: 5.7" HPA076115 Approved Centrosome,Cytosol NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 34: Testis cancer - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" Cytosol Centrosome "HPA076115: " "unprognostic (1.03e-1)" "unprognostic (3.49e-1)" ERVV-2 ENVV2 ENSG00000268964 "Endogenous retrovirus group V member 2, envelope" B6SEH9 19 53044740-53051680 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 14 "placenta: 7.9" "Cell type enriched" "Detected in some" 28 "Syncytiotrophoblasts: 133.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney Renal Papillary Cell Carcinoma (TCGA): 3.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 18 "testis cancer: 10.0" HPA076115 Approved Centrosome,Cytosol NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 48: Non-specific - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" Cytosol Centrosome "HPA076115: " "unprognostic (4.19e-1)" "unprognostic (1.21e-1)" ERVW-1 "envW, ERVWE1, HERV-7q, HERV-W, HERV-W-ENV, HERVW" ENSG00000242950 "Endogenous retrovirus group W member 1, envelope" Q9UQF0 7 92468380-92477986 "Essential proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "placenta: 51.3" "Group enriched" "Detected in some" 4 "Cytotrophoblasts: 306.9;Syncytiotrophoblasts: 1171.4" "Cell type enhanced" "Detected in single" "oligodendrocyte: 2.1" "Cancer enriched" "Detected in some" 40 "Testicular Germ Cell Tumor (TCGA): 61.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "Sarcoma: 24.7;testis cancer: 24.2" "Skin - Hair cortex cells, Skin - Inner root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" NA NA 47000 "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 6: Non-specific - Immune response" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" "unprognostic (1.12e-1)" "unprognostic (1.49e-1)" "unprognostic (1.84e-2)" "unprognostic (2.02e-1)" "unprognostic (4.82e-2)" "unprognostic (2.79e-1)" "unprognostic (6.70e-3)" ESAM W117m ENSG00000149564 "Endothelial cell adhesion molecule" Q96AP7 11 124752583-124762290 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Platelets: 1018.0;Vascular endothelial cells: 263.3" "Group enriched" "Detected in many" 21 "endothelial cell: 194.5;pericyte: 113.9;vascular associated smooth muscle cell: 101.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 8.2;naive B-cell: 7.5" "Group enriched" "Detected in many" 9 "B-cells: 7.5;granulocytes: 8.2;T-cells: 2.2" "Cancer enhanced" "Detected in many" "Leukemia: 19.0;pancreatic cancer: 16.2" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Lung - Endothelial cells, Minor Salivary Gland - Endothelial cells, Pancreas - Endothelial cells, Pituitary gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056293, HPA072563" Uncertain Approved "Cell Junctions,Cytosol" NA NA 4300000 "Cluster 20: Non-specific - DNA binding" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 2 "Cell Junctions" Cytosol "HPA056293: , HPA072563: " "unprognostic (6.99e-2)" "unprognostic (4.25e-2)" "unprognostic (2.69e-1)" "unprognostic (7.66e-3)" "unprognostic (1.88e-2)" "unprognostic (1.32e-2)" "unprognostic (6.04e-2)" "unprognostic (5.94e-2)" "unprognostic (1.76e-2)" "unprognostic (1.06e-1)" "validated prognostic favorable (7.17e-7)" "validated prognostic favorable (1.29e-5)" "unprognostic (1.53e-1)" "unprognostic (2.18e-1)" "unprognostic (4.82e-2)" "unprognostic (1.69e-1)" "unprognostic (7.65e-2)" "unprognostic (4.79e-3)" "unprognostic (1.83e-1)" "unprognostic (6.80e-2)" "unprognostic (5.19e-3)" "unprognostic (1.34e-1)" "unprognostic (9.60e-2)" "unprognostic (5.10e-2)" "unprognostic (3.38e-3)" "unprognostic (5.97e-2)" "unprognostic (4.07e-2)" "unprognostic (1.59e-2)" "unprognostic (5.32e-2)" "unprognostic (2.94e-1)" "unprognostic (2.50e-2)" ESCO1 "EFO1, ESO1, KIAA1911" ENSG00000141446 "Establishment of sister chromatid cohesion N-acetyltransferase 1" Q5FWF5 18 21529284-21600884 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Myonuclei: 233.4;Neutrophils: 225.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042497 Approved NA NA "Cluster 24: Non-specific - Transcription" "Cluster 39: Testis - Nuclear processes" "Cluster 16: Non-specific - Transcription" "Cluster 13: Non-specific - Mixed function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 3 "HPA042497: " "unprognostic (8.93e-2)" "unprognostic (3.60e-1)" "unprognostic (9.41e-2)" "unprognostic (2.19e-1)" "unprognostic (1.84e-1)" "unprognostic (1.65e-1)" "unprognostic (2.77e-1)" "unprognostic (2.44e-2)" "unprognostic (6.18e-2)" "unprognostic (7.58e-2)" "unprognostic (2.34e-1)" "unprognostic (1.40e-1)" "unprognostic (1.75e-1)" "unprognostic (3.66e-3)" "unprognostic (1.19e-1)" "unprognostic (9.87e-2)" "unprognostic (3.06e-2)" "unprognostic (1.99e-2)" "unprognostic (2.14e-2)" "unprognostic (3.86e-3)" "unprognostic (1.03e-1)" "unprognostic (3.50e-2)" "unprognostic (9.80e-3)" "unprognostic (1.62e-2)" "unprognostic (1.79e-1)" "unprognostic (3.60e-2)" "unprognostic (2.55e-2)" "unprognostic (1.52e-1)" "unprognostic (2.15e-1)" "unprognostic (3.05e-1)" "unprognostic (2.04e-1)" ESCO2 "EFO2, RBS" ENSG00000171320 "Establishment of sister chromatid cohesion N-acetyltransferase 2" Q56NI9 8 27771949-27812640 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle" "Acyltransferase, Transferase" "Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.6;intestine: 10.3;lymphoid tissue: 7.9;testis: 5.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 42.1;Differentiating spermatogonia: 77.7;Early primary spermatocytes: 127.1;Erythrocyte progenitors: 80.4;Megakaryocyte progenitors: 38.1;Monocyte progenitors: 49.1;Oocytes: 336.2" "Cell type enhanced" "Detected in some" "hippocampal CA4: 5.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.4" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA027243, HPA053679" Supported "Nucleoplasm,Golgi apparatus,Cell Junctions" Yes Yes "Cluster 9: T-regs - Cell cycle regulation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 9: Non-specific - Receptor signaling" "Cluster 40: Non-specific - Unknown function" "Cluster 41: Oocytes - Oogenesis" 11 Nucleoplasm "Golgi apparatus, Cell Junctions" "HPA027243: , HPA053679: " "unprognostic (4.54e-2)" "unprognostic (1.97e-1)" "unprognostic (5.63e-2)" "unprognostic (5.73e-2)" "potential prognostic favorable (9.95e-5)" "unprognostic (2.74e-1)" "unprognostic (1.21e-1)" "unprognostic (4.53e-3)" "unprognostic (3.10e-2)" "unprognostic (9.42e-3)" "unprognostic (3.12e-3)" "potential prognostic unfavorable (6.31e-4)" "unprognostic (1.42e-2)" "unprognostic (1.28e-3)" "unprognostic (8.08e-2)" "unprognostic (5.81e-2)" "unprognostic (5.31e-2)" "potential prognostic unfavorable (8.43e-4)" "unprognostic (2.22e-2)" "potential prognostic favorable (2.79e-5)" "unprognostic (3.33e-2)" "unprognostic (2.11e-2)" "unprognostic (5.19e-2)" "unprognostic (2.92e-1)" "unprognostic (2.55e-1)" ESD ENSG00000139684 "Esterase D" P10768 13 46771256-46797420 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Decidual stromal cells: 428.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039700 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 8100000 "Cluster 13: Non-specific - Mitochondria" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 19: Non-specific - Unknown function" "Cluster 62: Smooth muscle cells - Muscle contraction" 18 "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA039700: " "unprognostic (9.36e-2)" "unprognostic (1.85e-1)" "unprognostic (6.90e-2)" "unprognostic (3.07e-2)" "unprognostic (3.46e-2)" "unprognostic (5.67e-1)" "unprognostic (3.84e-2)" "unprognostic (3.12e-3)" "potential prognostic unfavorable (3.99e-5)" "unprognostic (7.44e-2)" "potential prognostic favorable (1.21e-11)" "unprognostic (2.27e-3)" "unprognostic (2.01e-2)" "unprognostic (3.36e-2)" "unprognostic (9.96e-3)" "unprognostic (1.16e-1)" "unprognostic (2.32e-2)" "unprognostic (4.44e-2)" "unprognostic (1.80e-1)" "unprognostic (3.95e-3)" "unprognostic (1.52e-2)" "unprognostic (2.69e-2)" "unprognostic (8.47e-2)" "unprognostic (8.57e-2)" "unprognostic (8.06e-2)" "unprognostic (2.27e-1)" "unprognostic (3.92e-2)" "unprognostic (2.28e-2)" "unprognostic (1.42e-1)" "unprognostic (7.23e-2)" "unprognostic (2.62e-1)" ESF1 "bA526K24.1, C20orf6" ENSG00000089048 "ESF1 nucleolar pre-rRNA processing protein homolog" Q9H501 20 13714322-13784919 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early primary spermatocytes: 286.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047083, HPA050396" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 24: Non-specific - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 17: Non-specific - RNA processing" 19 "Nucleoplasm, Nucleoli" "HPA047083: , HPA050396: " "unprognostic (9.44e-2)" "unprognostic (1.07e-1)" "unprognostic (3.62e-1)" "unprognostic (1.40e-2)" "unprognostic (1.51e-1)" "unprognostic (1.88e-1)" "unprognostic (2.12e-2)" "unprognostic (5.18e-2)" "unprognostic (2.19e-2)" "potential prognostic unfavorable (1.12e-4)" "potential prognostic favorable (7.86e-4)" "unprognostic (5.86e-2)" "unprognostic (8.04e-2)" "potential prognostic unfavorable (9.78e-7)" "unprognostic (1.65e-2)" "unprognostic (6.26e-3)" "unprognostic (1.42e-1)" "unprognostic (2.25e-1)" "unprognostic (1.39e-1)" "unprognostic (2.02e-1)" "unprognostic (4.03e-2)" "unprognostic (2.76e-3)" "potential prognostic unfavorable (5.22e-4)" "unprognostic (2.57e-2)" "unprognostic (6.41e-2)" "unprognostic (2.51e-2)" "unprognostic (1.43e-1)" "unprognostic (1.31e-1)" "unprognostic (2.01e-1)" "unprognostic (1.89e-2)" "unprognostic (1.19e-1)" ESM1 ENSG00000164283 "Endothelial cell specific molecule 1" Q9NQ30 5 54977867-55022671 "Predicted secreted proteins" Angiogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 18.6;thyroid gland: 16.2" "Cell type enhanced" "Detected in some" "Epididymal clear cells: 16.3;Lacrimal acinar cells: 6.3;Platelets: 7.1;Salivary acinar cells: 17.1;Salivary basal cells: 5.0;Salivary duct cells: 16.4;Salivary ionocytes: 17.4;Salivary myoepithelial cells: 5.8;Vascular endothelial cells: 36.9" "Group enriched" "Detected in some" 7 "endothelial cell: 3.2;ependymal cell: 7.0;fibroblast: 6.8;leukocyte: 3.0" "Cancer enriched" "Detected in all" 7 "Kidney Renal Clear Cell Carcinoma (TCGA): 213.8" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "NK-cell: 1.4" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "ovarian cancer: 67.4;Sarcoma: 47.6;thyroid cancer: 85.4" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in single" "Region enhanced" "Detected in some" "midbrain: 3.6" "CAB047364, HPA075535" Approved Approved Vesicles "Secreted to blood" "Developmental protein" NA NA 1540000 610000 "Cluster 1: T-cells - Unknown function" "Cluster 72: Kidney - Transmembrane transport" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 72: Neuronal - Signal transduction" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 8 Vesicles "CAB047364: , HPA075535: " "unprognostic (1.45e-2)" "unprognostic (2.76e-2)" "unprognostic (3.29e-2)" "potential prognostic unfavorable (1.66e-6)" "unprognostic (2.88e-2)" "unprognostic (4.33e-2)" "unprognostic (1.84e-2)" "unprognostic (4.07e-2)" "unprognostic (2.14e-1)" "unprognostic (9.64e-2)" "validated prognostic favorable (4.98e-7)" "validated prognostic favorable (2.83e-4)" "unprognostic (3.61e-3)" "unprognostic (7.58e-3)" "unprognostic (2.76e-3)" "unprognostic (3.25e-2)" "unprognostic (4.57e-3)" "unprognostic (2.62e-2)" "unprognostic (2.86e-1)" "unprognostic (3.07e-2)" "unprognostic (1.52e-3)" "unprognostic (1.64e-1)" "unprognostic (9.93e-2)" "unprognostic (9.13e-3)" "unprognostic (1.29e-1)" "unprognostic (2.58e-2)" "unprognostic (3.03e-1)" "unprognostic (1.43e-2)" "unprognostic (2.04e-1)" "unprognostic (8.68e-2)" "unprognostic (2.89e-2)" ESPL1 "ESP1, KIAA0165, SEPA" ENSG00000135476 "Extra spindle pole bodies like 1, separase" Q14674 12 53268299-53293638 "Enzymes, Essential proteins, Predicted intracellular proteins, Predicted membrane proteins" "Chromosome partition" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 8.0;esophagus: 14.2;lymphoid tissue: 9.9" "Cell type enriched" "Detected in many" 4 "Esophageal apical cells: 161.8" "Low cell type specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 16.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Thyroid gland - Mitotic cells (Thyroid)" "Not detected" "Not detected" "Not detected" "Not detected" "CAB012185, HPA073188" Approved Supported Nucleoplasm,Vesicles NA Yes "Cluster 9: T-regs - Cell cycle regulation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 38: Non-specific - Transcription" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 11 Nucleoplasm Vesicles "CAB012185: , HPA073188: " "unprognostic (2.28e-2)" "unprognostic (1.44e-1)" "unprognostic (2.38e-2)" "unprognostic (9.04e-3)" "unprognostic (1.20e-1)" "unprognostic (2.65e-1)" "unprognostic (3.15e-1)" "unprognostic (7.91e-2)" "unprognostic (2.53e-1)" "potential prognostic unfavorable (3.13e-4)" "potential prognostic unfavorable (2.77e-4)" "unprognostic (1.98e-3)" "validated prognostic unfavorable (1.25e-4)" "validated prognostic unfavorable (1.36e-4)" "unprognostic (3.39e-1)" "unprognostic (2.76e-2)" "unprognostic (2.30e-1)" "unprognostic (3.83e-2)" "unprognostic (2.43e-3)" "potential prognostic unfavorable (3.50e-4)" "unprognostic (1.74e-2)" "unprognostic (1.42e-2)" "unprognostic (9.08e-3)" "unprognostic (5.21e-2)" "unprognostic (2.39e-1)" "unprognostic (9.49e-2)" ESPN DFNB36 ENSG00000187017 Espin B1AK53 1 6424776-6461367 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hearing Actin-binding "Deafness, Disease variant, Non-syndromic deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 170.3;retina: 109.8;testis: 159.4" "Cell type enhanced" "Detected in many" "Colonocytes: 166.2;Cone photoreceptor cells: 147.0;Early spermatids: 178.3;Enterocytes: 491.5;Hepatocytes: 117.3;Late spermatids: 849.6;Müller glia: 289.5;Proximal tubule cells: 121.5;Rod photoreceptor cells: 183.4;Sertoli cells: 157.8" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 29.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 92.9" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary gland basal cells, Skin - Keratinocyte (other), Testis - Sertoli cells" "Low region specificity" "Detected in some" "Region enhanced" "Detected in some" "cerebellum: 4.0" "HPA028674, HPA060220" Enhanced Approved Vesicles NA NA "Cluster 47: Testis - Mixed function" "Cluster 35: Non-specific - DNA binding" "Cluster 47: Leukemia - Hemostasis" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 6 Vesicles "HPA028674: , HPA060220: " "unprognostic (1.54e-1)" "unprognostic (8.53e-2)" "unprognostic (8.98e-2)" "unprognostic (6.37e-2)" "unprognostic (2.09e-1)" "unprognostic (1.07e-3)" "unprognostic (2.52e-2)" "unprognostic (5.07e-2)" "unprognostic (1.13e-1)" "validated prognostic favorable (2.97e-5)" "validated prognostic favorable (6.16e-5)" "unprognostic (1.50e-3)" "unprognostic (1.18e-1)" "unprognostic (1.11e-1)" "unprognostic (2.50e-2)" "unprognostic (1.11e-1)" "unprognostic (4.42e-1)" "unprognostic (2.44e-2)" "unprognostic (4.40e-2)" "unprognostic (1.03e-1)" "unprognostic (7.11e-3)" "unprognostic (1.69e-1)" "unprognostic (2.57e-2)" "unprognostic (3.49e-1)" "unprognostic (5.87e-2)" "unprognostic (1.71e-1)" "unprognostic (2.58e-1)" "unprognostic (2.92e-1)" "unprognostic (3.84e-2)" "unprognostic (3.82e-2)" ESPNL FLJ42568 ENSG00000144488 "Espin like" Q6ZVH7 2 238100340-238133287 "Predicted intracellular proteins" Hearing Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.2;intestine: 3.3" "Cell type enriched" "Detected in some" 4 "Gonadotrophs: 20.6" "Cell type enhanced" "Detected in some" "upper rhombic lip: 4.7" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in some" 5 "cerebellum: 10.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 2.8" "Liver - Hepatocytes, Pituitary gland - Gonadotropes" "Not detected" "Not detected" "Not detected" "Not detected" HPA055103 Uncertain Approved "Nucleoplasm,Nuclear bodies,Vesicles,Cytosol" NA NA "Cluster 64: Non-specific - Transcription" "Cluster 35: Non-specific - DNA binding" "Cluster 11: Neuronal - Sensory perception" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 3 Cytosol "Nucleoplasm, Nuclear bodies, Vesicles" "HPA055103: " "potential prognostic favorable (8.47e-4)" "unprognostic (5.95e-2)" "unprognostic (1.93e-1)" "unprognostic (4.46e-1)" "unprognostic (1.83e-1)" "unprognostic (3.26e-1)" ESR1 "ER-alpha, Era, ESR, NR3A1" ENSG00000091831 "Estrogen receptor 1" P03372 6 151656691-152129619 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Cancer-related genes, Disease variant, FDA approved drug targets, Osteoporosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 80.7;endometrium 1: 103.7;fallopian tube: 61.1" "Cell type enhanced" "Detected in many" "Adipocytes: 391.0;Breast hormone-responsive cells: 507.0;Endometrial ciliated cells: 572.2;Endometrial glandular cells: 463.2;Endometrial luminal cells: 449.7;Endometrial stromal cells: 737.2;Epicardial cells: 436.6;Epididymal efferent duct absorptive cells: 946.8;Fallopian secretory cells: 405.0;Gonadotrophs: 1651.4;Hepatocytes: 394.3;Lactotrophs: 377.5;Retinal horizontal cells: 803.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 132.3;Uterine Corpus Endometrial Carcinoma (TCGA): 57.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 20.8" "Breast - Breast glandular cells, Kidney - Fibroblasts, Liver - Hepatocytes, Pituitary gland - Gonadotropes, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB000037, HPA000449, HPA000450, CAB055099, CAB072858" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 75: Ovary - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 27: Breast cancer - Unknown function" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 572 Vesicles Nucleoplasm "CAB000037: , CAB055099: , CAB072858: , HPA000449: , HPA000450: " "unprognostic (1.02e-1)" "unprognostic (2.06e-2)" "unprognostic (1.67e-1)" "unprognostic (8.50e-2)" "unprognostic (6.55e-2)" "potential prognostic favorable (1.23e-4)" "unprognostic (3.05e-2)" "potential prognostic favorable (3.01e-4)" "unprognostic (6.60e-2)" "validated prognostic favorable (3.29e-5)" "validated prognostic favorable (1.09e-9)" "unprognostic (1.04e-1)" "unprognostic (1.71e-1)" "unprognostic (1.69e-2)" "unprognostic (1.14e-2)" "unprognostic (8.06e-2)" "unprognostic (3.43e-1)" "unprognostic (1.22e-1)" "unprognostic (9.78e-2)" "unprognostic (7.71e-2)" "unprognostic (2.47e-2)" ESR2 "ER-beta, Erb, NR3A2" ENSG00000140009 "Estrogen receptor 2" Q92731 14 64084232-64338112 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 6.5;ovary: 6.2;testis: 5.6" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 212.8;Cardiomyocytes: 389.3;Epicardial cells: 909.7;Myonuclei: 183.5;Rod photoreceptor cells: 291.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "lymphoma: 5.6" "Adipose subcutaneous - Adipocytes (Subcutaneous)" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebellum: 10.0" "HPA068406, CAB079300" Enhanced Supported Nucleoplasm,Vesicles NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 75: Ovary - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 68 Nucleoplasm Vesicles "CAB079300: , HPA068406: " "unprognostic (1.12e-3)" "unprognostic (3.19e-1)" "unprognostic (5.24e-2)" "unprognostic (1.53e-2)" "unprognostic (4.20e-2)" "unprognostic (1.92e-1)" "unprognostic (1.48e-1)" "unprognostic (2.72e-1)" "unprognostic (2.58e-2)" ESRP1 "FLJ20171, RBM35A" ENSG00000104413 "Epithelial splicing regulatory protein 1" Q6NXG1 8 94641074-94707466 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 639.3;Esophageal suprabasal cells: 236.1;Foveolar cells: 227.0;Goblet cells: 209.7" "Cell type enhanced" "Detected in some" "lower rhombic lip: 3.8;thalamic excitatory: 3.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Liver - Cholangiocytes, Lung - Alveolar cells type 2, Skin - Keratinocyte (other), Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA023719, HPA023720, HPA067104" Enhanced Enhanced "Nucleoplasm,Nuclear bodies" NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 70: Intestinal goblet cells - Mucin production" 32 "Nuclear bodies" Nucleoplasm "HPA023719: , HPA023720: , HPA067104: " "unprognostic (4.17e-3)" "potential prognostic unfavorable (1.17e-4)" "unprognostic (1.73e-1)" "unprognostic (1.18e-2)" "unprognostic (1.48e-2)" "unprognostic (3.75e-1)" "unprognostic (2.12e-2)" "potential prognostic unfavorable (2.45e-4)" "unprognostic (5.59e-2)" "unprognostic (1.10e-1)" "unprognostic (7.25e-2)" "unprognostic (2.35e-1)" "unprognostic (5.57e-2)" "unprognostic (7.93e-3)" "unprognostic (1.19e-1)" "unprognostic (1.49e-1)" "unprognostic (2.60e-3)" "unprognostic (5.34e-2)" "potential prognostic unfavorable (2.47e-4)" "unprognostic (1.39e-2)" "unprognostic (8.25e-3)" "unprognostic (1.77e-1)" "unprognostic (1.13e-2)" "unprognostic (1.56e-2)" "unprognostic (6.83e-2)" "unprognostic (2.56e-1)" "unprognostic (1.05e-1)" "unprognostic (4.24e-2)" ESRP2 "FLJ21918, RBM35B" ENSG00000103067 "Epithelial splicing regulatory protein 2" Q9H6T0 16 68229033-68238102 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 64.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 46.9;Esophageal apical cells: 142.2;Esophageal suprabasal cells: 100.3;Late spermatids: 141.9;Syncytiotrophoblasts: 71.3" "Cell type enriched" "Detected in single" 5 "choroid plexus epithelial cell: 2.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Pituitary gland - Corticotropes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA040751, HPA048597, HPA048618" Uncertain Enhanced Nucleoplasm NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 4 Nucleoplasm "HPA040751: , HPA048597: , HPA048618: " "unprognostic (9.91e-2)" "unprognostic (4.03e-2)" "unprognostic (1.42e-1)" "unprognostic (1.33e-1)" "unprognostic (2.15e-1)" "unprognostic (3.13e-1)" "unprognostic (4.32e-2)" "unprognostic (9.30e-3)" "unprognostic (3.52e-3)" "unprognostic (6.94e-3)" "unprognostic (3.80e-2)" "unprognostic (1.30e-1)" "unprognostic (1.16e-3)" "unprognostic (9.39e-2)" "unprognostic (1.45e-1)" "unprognostic (8.51e-2)" "unprognostic (9.64e-2)" "unprognostic (3.48e-1)" "unprognostic (5.85e-2)" "unprognostic (1.73e-2)" "unprognostic (8.28e-2)" "unprognostic (2.22e-1)" "unprognostic (7.63e-2)" "potential prognostic unfavorable (3.27e-4)" "unprognostic (8.64e-2)" "unprognostic (4.21e-1)" "unprognostic (4.39e-1)" "unprognostic (1.14e-1)" "unprognostic (1.07e-1)" ESRRA "ERR1, ERRa, ERRalpha, ESRL1, NR3B1" ENSG00000173153 "Estrogen related receptor alpha" P11474 11 64305497-64316743 "Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 179.8" "Cell type enhanced" "Detected in many" "Colonocytes: 198.7;Enterocytes: 212.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053785, HPA077297" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium" Yes No "Cluster 7: Non-specific - Innate immune response" "Cluster 52: Non-specific - Cellular respiration" "Cluster 18: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 22 "Nucleoplasm, Nucleoli fibrillar center" "Microtubules, Cytokinetic bridge, Mitotic spindle, Primary cilium" "HPA053785: , HPA077297: " "unprognostic (5.17e-2)" "unprognostic (1.18e-2)" "unprognostic (1.23e-2)" "unprognostic (2.12e-1)" "unprognostic (6.50e-2)" "unprognostic (7.76e-2)" "unprognostic (1.57e-1)" "unprognostic (1.99e-1)" "unprognostic (8.12e-2)" "unprognostic (7.13e-2)" "potential prognostic favorable (5.69e-6)" "unprognostic (2.09e-1)" "unprognostic (1.70e-3)" "unprognostic (5.76e-2)" "unprognostic (2.00e-1)" "unprognostic (1.95e-1)" "unprognostic (1.73e-2)" "unprognostic (1.72e-1)" "unprognostic (3.08e-1)" "unprognostic (2.49e-2)" "unprognostic (2.01e-1)" "unprognostic (2.03e-2)" "unprognostic (8.04e-2)" "unprognostic (3.10e-2)" "unprognostic (4.76e-2)" "unprognostic (4.49e-2)" "unprognostic (2.14e-1)" "unprognostic (2.78e-2)" "unprognostic (6.77e-2)" "unprognostic (1.16e-2)" "unprognostic (3.75e-1)" ESRRB "DFNB35, ERR2, ERRb, ERRbeta, ESRL2, NR3B2" ENSG00000119715 "Estrogen related receptor beta" O95718 14 76310712-76501837 "Disease related genes, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "kidney: 15.2;retina: 33.9" "Group enriched" "Detected in many" 5 "Distal convoluted tubule cells: 461.0;Loop of henle epithelial cells: 497.0;Myonuclei: 261.2;Retinal horizontal cells: 452.8;Rod photoreceptor cells: 838.4" "Group enriched" "Detected in many" 4 "central nervous system macrophage: 23.6;choroid plexus epithelial cell: 61.0" "Cancer enriched" "Detected in single" 5 "Kidney Chromophobe (TCGA): 3.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 3.9" "Heart muscle - Cardiomyocytes, Kidney - Ascending Loop of Henle cells, Skeletal muscle - Skeletal myocytes, Stomach - Parietal cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" HPA074772 Supported Nucleoplasm,Cytosol NA NA "Cluster 42: Retina - Visual perception" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 79: Photoreceptor cells - Phototransduction" 4 Nucleoplasm Cytosol "HPA074772: " "unprognostic (7.12e-2)" "unprognostic (1.07e-1)" ESRRG "ERR-gamma, ERRg, NR3B3" ENSG00000196482 "Estrogen related receptor gamma" P62508 1 216503246-217137755 "FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 27.1;parathyroid gland: 43.5;retina: 33.5;stomach 1: 33.1" "Cell type enhanced" "Detected in many" "Bergmann glia: 2711.2;Distal convoluted tubule cells: 6180.5;Loop of henle epithelial cells: 3812.1;Parietal cells: 1371.9;Renal collecting duct intercalated cells: 3411.9;Renal connecting tubule cells: 4138.3" "Cell type enhanced" "Detected in all" "Bergmann glia: 2637.2" "Cancer enriched" "Detected in many" 5 "Kidney Chromophobe (TCGA): 18.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 14.7" "Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Prostate - Prostate glandular cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Skin - Eccrine sweat gland cells, Stomach - Parietal cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044678 Uncertain Approved Nucleoplasm No NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 49: Hindbrain - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 25 Nucleoplasm "HPA044678: " "unprognostic (4.12e-2)" "unprognostic (2.01e-2)" "unprognostic (2.54e-2)" "unprognostic (4.38e-2)" "unprognostic (2.99e-1)" "unprognostic (1.05e-1)" "unprognostic (8.80e-2)" "potential prognostic favorable (7.11e-8)" "unprognostic (1.51e-2)" "unprognostic (5.77e-2)" "unprognostic (2.72e-2)" "unprognostic (6.85e-2)" "unprognostic (1.06e-1)" "unprognostic (7.35e-3)" "unprognostic (1.29e-1)" "unprognostic (1.00e-1)" "unprognostic (3.99e-2)" "unprognostic (5.18e-2)" "unprognostic (3.61e-2)" "unprognostic (2.55e-1)" "potential prognostic unfavorable (5.35e-4)" "unprognostic (3.25e-1)" ESS2 "bis1, DGCR13, DGCR14, DGS-H, DGSI, ES2, Es2el, ESS-2" ENSG00000100056 "Ess-2 splicing factor homolog" Q96DF8 22 19130279-19144684 "Essential proteins, Human disease related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 4.7" "Cell type enriched" "Detected in many" 4 "Late spermatids: 3408.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001221, HPA001222" Enhanced Approved Nucleoplasm NA NA "Cluster 67: Testis - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 66: Non-specific - Mitochondria" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 29 Nucleoplasm "HPA001221: , HPA001222: " "unprognostic (9.44e-2)" "potential prognostic favorable (7.50e-4)" "unprognostic (1.58e-1)" "unprognostic (8.27e-2)" "unprognostic (2.32e-3)" "unprognostic (1.34e-1)" "potential prognostic favorable (1.58e-4)" "unprognostic (9.72e-2)" "unprognostic (6.39e-2)" "unprognostic (1.13e-2)" "unprognostic (1.09e-1)" "unprognostic (5.05e-1)" "unprognostic (1.98e-1)" ESX1 "ESX1L, ESXR1" ENSG00000123576 "ESX homeobox 1" Q8N693 X 104250038-104254933 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 69 "testis: 8.4" "Group enriched" "Detected in some" 4 "Differentiating spermatogonia: 155.7;Undifferentiated spermatogonia: 50.5" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "Testicular Germ Cell Tumor (TCGA): 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Adrenocortical cancer: 4.7" "Testis - Spermatogonia" "Not detected" "Not detected" "HPA051992, HPA073330" Enhanced Supported "Nuclear speckles" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 106: Spermatogonia - Spermatogonial differentiation" "Nuclear speckles" "HPA051992: , HPA073330: " "unprognostic (2.17e-1)" ESYT1 "FAM62A, KIAA0747, MBC2" ENSG00000139641 "Extended synaptotagmin 1" Q9BSJ8 12 56118250-56144674 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal efferent duct ciliated cells: 82.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016858, HPA076926" Approved Supported "Endoplasmic reticulum" NA NA 1000000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 49: Hindbrain - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 58: Mast cells - Allergic inflammatory responses" 114 "Endoplasmic reticulum" "HPA016858: , HPA076926: " "unprognostic (8.25e-3)" "unprognostic (2.96e-2)" "unprognostic (6.51e-2)" "unprognostic (9.90e-3)" "unprognostic (4.34e-2)" "unprognostic (2.94e-1)" "unprognostic (8.39e-2)" "unprognostic (3.69e-3)" "unprognostic (2.84e-1)" "unprognostic (4.01e-3)" "potential prognostic favorable (9.54e-8)" "unprognostic (5.20e-2)" "unprognostic (1.32e-1)" "unprognostic (3.71e-2)" "unprognostic (1.06e-2)" "unprognostic (3.31e-1)" "unprognostic (5.87e-3)" "unprognostic (2.15e-1)" "unprognostic (2.47e-2)" "unprognostic (2.96e-1)" "unprognostic (4.13e-2)" "unprognostic (6.95e-3)" "unprognostic (1.91e-1)" "unprognostic (3.23e-1)" "unprognostic (1.11e-1)" "unprognostic (1.50e-3)" "unprognostic (1.81e-1)" "unprognostic (1.36e-1)" "unprognostic (1.84e-2)" "unprognostic (1.13e-1)" "unprognostic (7.60e-2)" ESYT2 "CHR2SYT, FAM62B, KIAA1228" ENSG00000117868 "Extended synaptotagmin 2" A0FGR8 7 158730995-158830253 "Plasma proteins, Predicted membrane proteins, Transporters" "Endocytosis, Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Somatotrophs: 922.7;Vascular smooth muscle cells: 875.1" "Cell type enhanced" "Detected in all" "endothelial cell: 1378.2;vascular associated smooth muscle cell: 1373.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002132, HPA070823" Approved Approved "Plasma membrane,Cytosol" NA NA 6300 "Cluster 1: T-cells - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 1: Neurons - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 103: Non-specific - Basic cellular processes" 54 "Plasma membrane, Cytosol" "HPA002132: , HPA070823: " "unprognostic (2.24e-2)" "unprognostic (5.02e-2)" "unprognostic (4.04e-1)" "unprognostic (6.49e-3)" "unprognostic (1.51e-1)" "unprognostic (1.53e-2)" "unprognostic (7.51e-2)" "unprognostic (2.69e-2)" "unprognostic (3.06e-2)" "unprognostic (1.17e-2)" "potential prognostic favorable (1.05e-5)" "unprognostic (3.21e-1)" "unprognostic (1.00e-1)" "unprognostic (8.50e-2)" "unprognostic (5.44e-3)" "unprognostic (1.59e-2)" "unprognostic (1.07e-3)" "unprognostic (2.92e-3)" "unprognostic (5.64e-2)" "unprognostic (2.15e-2)" "unprognostic (1.27e-1)" "unprognostic (1.11e-3)" "unprognostic (7.54e-3)" "unprognostic (5.02e-1)" "unprognostic (1.19e-2)" "unprognostic (6.72e-2)" "unprognostic (3.56e-1)" "unprognostic (1.09e-1)" "unprognostic (8.72e-2)" "unprognostic (1.18e-3)" "unprognostic (2.34e-1)" ESYT3 "CHR3SYT, FAM62C" ENSG00000158220 "Extended synaptotagmin 3" A0FGR9 3 138434586-138481686 "Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.2;lung: 4.4;skin 1: 6.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 65.2;Alveolar cells type 2: 75.8;Brain excitatory neurons: 20.6;Cardiomyocytes: 56.1;Epicardial cells: 38.7;Gonadotrophs: 24.0;Oocytes: 23.0;Pituicytes/FSCs: 21.6;Transitional alveolar cells: 34.3" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Thyroid Carcinoma (TCGA): 3.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Skin - Keratinocyte (granular), Testis - Spermatogonia" "Region enhanced" "Detected in many" "hypothalamus: 7.3" "Low region specificity" "Detected in all" HPA039200 Approved NA NA "Cluster 2: Non-specific - Mixed function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 29: Non-specific - Unknown function" "Cluster 81: Alveolar cells - Lung function" 2 "HPA039200: " "unprognostic (5.23e-2)" "unprognostic (1.30e-1)" "potential prognostic favorable (1.41e-4)" "unprognostic (7.18e-2)" "unprognostic (1.48e-1)" "unprognostic (3.75e-3)" "unprognostic (3.81e-1)" ETAA1 ETAA16 ENSG00000143971 "ETAA1 activator of ATR kinase" Q9NY74 2 67397322-67412089 "Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035048, HPA035049" Uncertain Supported "Nucleoplasm,Nuclear speckles,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 18: Adrenal cortex cells - Steroidogensis" 10 Nucleoplasm "Nuclear speckles, Vesicles, Plasma membrane, Cytosol" "HPA035048: , HPA035049: " "unprognostic (3.18e-2)" "unprognostic (2.17e-1)" "unprognostic (2.06e-2)" "unprognostic (1.19e-1)" "unprognostic (2.99e-1)" "unprognostic (1.66e-1)" "unprognostic (3.30e-1)" "unprognostic (1.04e-1)" "unprognostic (2.14e-2)" "unprognostic (2.51e-1)" "potential prognostic favorable (3.31e-4)" "unprognostic (2.80e-2)" "unprognostic (3.14e-1)" "unprognostic (1.93e-2)" "unprognostic (4.15e-3)" "unprognostic (2.05e-1)" "unprognostic (7.93e-2)" "unprognostic (9.32e-2)" "unprognostic (4.16e-2)" "unprognostic (1.38e-1)" "unprognostic (8.25e-2)" "unprognostic (8.44e-2)" "unprognostic (4.67e-2)" "unprognostic (3.24e-1)" "unprognostic (1.79e-2)" "unprognostic (9.50e-2)" "unprognostic (1.06e-2)" "unprognostic (5.11e-2)" "unprognostic (4.37e-1)" "unprognostic (7.51e-2)" "unprognostic (7.37e-2)" ETDA ENSG00000238210 "Embryonic testis differentiation homolog A" Q3ZM63 X 135252061-135253583 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 24 "testis: 16.3" "Group enriched" "Detected in some" 11 "Early spermatids: 49.5;Late primary spermatocytes: 53.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" ETDB LINC00633 ENSG00000224107 "Embryonic testis differentiation homolog B" P0DPP9 X 135118955-135120526 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 31 "testis: 11.2" "Group enriched" "Detected in some" 7 "Early spermatids: 16.7;Late primary spermatocytes: 15.1" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" ETDC ENSG00000283644 "Embryonic testis differentiation homolog C" A0A1B0GVM5 X 135309480-135309659 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "skin 1: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" NA NA "Cluster 40: Non-specific - Mixed function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 72: Neuronal - Signal transduction" "unprognostic (2.41e-1)" "unprognostic (9.08e-2)" ETF1 "ERF, ERF1, RF1, SUP45L1, TB3-1" ENSG00000120705 "Eukaryotic translation termination factor 1" P62495 5 138506095-138543236 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Nonsense-mediated mRNA decay, Protein biosynthesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 496.9;Esophageal apical cells: 432.9;Neutrophils: 1218.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011686, HPA037511" Approved NA NA 610000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 19 "CAB011686: , HPA037511: " "unprognostic (2.85e-1)" "unprognostic (2.17e-2)" "unprognostic (2.89e-1)" "unprognostic (2.71e-1)" "unprognostic (5.91e-3)" "unprognostic (1.84e-2)" "unprognostic (3.24e-1)" "unprognostic (1.30e-3)" "unprognostic (2.92e-3)" "unprognostic (3.58e-2)" "potential prognostic favorable (3.87e-6)" "unprognostic (1.06e-1)" "unprognostic (1.85e-1)" "potential prognostic unfavorable (3.44e-4)" "unprognostic (9.54e-3)" "unprognostic (8.96e-3)" "unprognostic (8.17e-2)" "unprognostic (1.81e-1)" "unprognostic (1.58e-1)" "unprognostic (1.04e-1)" "potential prognostic unfavorable (9.79e-4)" "unprognostic (2.83e-2)" "unprognostic (2.01e-2)" "unprognostic (9.09e-2)" "unprognostic (3.02e-3)" "unprognostic (2.66e-1)" "unprognostic (1.42e-1)" "unprognostic (2.14e-1)" "unprognostic (5.32e-2)" "potential prognostic unfavorable (6.74e-4)" "unprognostic (2.68e-1)" ETFA "EMA, GA2, MADD" ENSG00000140374 "Electron transfer flavoprotein subunit alpha" P13804 15 76188555-76311730 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Electron transport, Transport" "Disease variant, Glutaricaciduria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 244.8;tongue: 244.5" "Cell type enhanced" "Detected in all" "Hepatocytes: 523.5;Platelets: 913.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018990, HPA018993, HPA018996, HPA024089" Enhanced Enhanced Mitochondria NA NA 450000 "Cluster 33: Non-specific - ATP binding" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 58: Non-specific - Nuclear processes" "Cluster 47: Platelets - Hemostasis" 33 Mitochondria "HPA018990: , HPA018993: , HPA018996: , HPA024089: " "unprognostic (4.41e-2)" "unprognostic (4.25e-3)" "unprognostic (8.69e-2)" "unprognostic (1.63e-1)" "unprognostic (3.15e-2)" "unprognostic (1.92e-2)" "unprognostic (6.89e-3)" "unprognostic (1.40e-2)" "unprognostic (3.59e-2)" "unprognostic (8.65e-3)" "potential prognostic favorable (4.97e-12)" "unprognostic (4.06e-3)" "unprognostic (4.40e-3)" "unprognostic (3.77e-2)" "unprognostic (7.86e-3)" "unprognostic (7.91e-2)" "unprognostic (1.83e-3)" "unprognostic (2.71e-2)" "unprognostic (2.75e-1)" "unprognostic (7.91e-2)" "unprognostic (1.29e-1)" "unprognostic (1.35e-3)" "unprognostic (2.21e-1)" "unprognostic (1.44e-1)" "unprognostic (5.27e-2)" "unprognostic (5.07e-2)" "unprognostic (1.71e-1)" "unprognostic (2.65e-1)" "unprognostic (2.25e-2)" "unprognostic (8.06e-3)" "unprognostic (3.65e-1)" ETFB ENSG00000105379 "Electron transfer flavoprotein subunit beta" P38117 19 51345169-51366388 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Electron transport, Transport" "Disease variant, Glutaricaciduria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 489.9" "Cell type enhanced" "Detected in all" "Enterocytes: 644.9;Esophageal apical cells: 556.7;Esophageal suprabasal cells: 493.5;Hepatocytes: 1286.2;Late spermatids: 571.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018910, HPA018921, HPA018923" Supported Enhanced Mitochondria NA NA 100000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 76: Non-specific - Metabolism" "Cluster 27: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 97: Non-specific - Cellular respiration" 24 Mitochondria "HPA018910: , HPA018921: , HPA018923: " "unprognostic (8.59e-2)" "unprognostic (8.71e-2)" "unprognostic (8.78e-2)" "unprognostic (3.37e-2)" "unprognostic (1.83e-1)" "unprognostic (1.38e-1)" "unprognostic (3.56e-2)" "unprognostic (2.61e-1)" "unprognostic (2.88e-2)" "unprognostic (2.26e-1)" "potential prognostic favorable (4.51e-5)" "unprognostic (2.17e-1)" "potential prognostic favorable (7.52e-4)" "unprognostic (3.83e-1)" "unprognostic (5.73e-3)" "potential prognostic unfavorable (1.72e-4)" "unprognostic (2.64e-1)" "unprognostic (4.15e-2)" "unprognostic (1.35e-1)" "unprognostic (2.00e-1)" "unprognostic (3.52e-3)" "unprognostic (1.73e-1)" "unprognostic (2.11e-3)" "unprognostic (3.14e-1)" "unprognostic (1.89e-1)" "unprognostic (3.96e-1)" "unprognostic (5.19e-2)" "unprognostic (2.23e-1)" "unprognostic (1.25e-1)" "unprognostic (1.72e-1)" "unprognostic (9.93e-2)" ETFBKMT "C12orf72, DKFZp451L235, METTL20, MGC50559" ENSG00000139160 "Electron transfer flavoprotein subunit beta lysine methyltransferase" Q8IXQ9 12 31647160-31673114 "Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 37.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" HPA039024 Uncertain NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 34: Non-specific - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 65: Non-specific - Cell growth & division" 13 "HPA039024: " "unprognostic (2.68e-1)" "unprognostic (2.95e-1)" "unprognostic (6.82e-2)" "unprognostic (1.10e-1)" "unprognostic (2.88e-1)" "unprognostic (9.53e-2)" "unprognostic (7.99e-2)" "unprognostic (5.92e-2)" "unprognostic (2.24e-2)" "potential prognostic favorable (2.01e-5)" "unprognostic (1.06e-3)" "unprognostic (2.19e-2)" "unprognostic (1.21e-2)" "unprognostic (5.81e-2)" "unprognostic (1.23e-1)" "unprognostic (2.58e-1)" "unprognostic (3.20e-1)" "unprognostic (1.92e-2)" "unprognostic (5.32e-2)" "unprognostic (2.85e-1)" "unprognostic (5.67e-2)" "unprognostic (3.85e-1)" "unprognostic (1.17e-1)" "unprognostic (2.14e-2)" "unprognostic (5.62e-3)" "unprognostic (7.53e-2)" "unprognostic (5.39e-2)" "unprognostic (1.33e-1)" "unprognostic (2.94e-1)" ETFDH ETFQO ENSG00000171503 "Electron transfer flavoprotein dehydrogenase" Q16134 4 158671968-158710742 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Transport" Oxidoreductase "Disease variant, FDA approved drug targets, Glutaricaciduria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 148.9;tongue: 162.8" "Cell type enhanced" "Detected in many" "Myonuclei: 241.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041978, HPA058140" Enhanced Supported Nucleoplasm,Mitochondria,Cytosol NA NA 3700 "Cluster 25: Non-specific - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 55: Myocytes - Oxidative muscle function" 5 Mitochondria "Nucleoplasm, Cytosol" "HPA041978: , HPA058140: " "unprognostic (2.87e-1)" "unprognostic (5.95e-3)" "unprognostic (2.33e-1)" "unprognostic (1.53e-1)" "unprognostic (4.98e-3)" "unprognostic (2.61e-1)" "unprognostic (4.62e-1)" "unprognostic (1.26e-1)" "unprognostic (3.42e-2)" "unprognostic (1.18e-2)" "validated prognostic favorable (2.13e-10)" "validated prognostic favorable (5.12e-5)" "unprognostic (1.33e-2)" "unprognostic (2.90e-2)" "unprognostic (1.29e-2)" "unprognostic (2.85e-1)" "unprognostic (1.79e-1)" "unprognostic (2.01e-1)" "unprognostic (1.72e-1)" "unprognostic (3.06e-1)" "unprognostic (1.10e-1)" "unprognostic (1.24e-1)" "unprognostic (2.70e-1)" "unprognostic (9.76e-2)" "unprognostic (3.78e-2)" "unprognostic (3.28e-2)" "unprognostic (1.01e-2)" "unprognostic (1.53e-2)" "unprognostic (1.71e-1)" "potential prognostic unfavorable (6.28e-4)" "unprognostic (4.02e-2)" ETFRF1 LYRM5 ENSG00000205707 "Electron transfer flavoprotein regulatory factor 1" Q6IPR1 12 25195216-25209645 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 220.2;Late primary spermatocytes: 714.0;Parietal cells: 275.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Bile duct cancer: 107.2" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Liver - Hepatocytes, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044255 Approved NA NA "Cluster 24: Non-specific - Transcription" "Cluster 76: Non-specific - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 14 "HPA044255: " "unprognostic (7.21e-2)" "unprognostic (9.76e-2)" "unprognostic (2.83e-2)" "unprognostic (1.10e-1)" "unprognostic (3.60e-2)" "unprognostic (1.88e-1)" "unprognostic (2.36e-2)" "unprognostic (3.64e-2)" "unprognostic (4.40e-3)" "potential prognostic favorable (1.85e-5)" "unprognostic (6.45e-2)" "unprognostic (1.04e-2)" "unprognostic (1.20e-3)" "unprognostic (8.62e-2)" "unprognostic (1.31e-1)" "unprognostic (2.81e-2)" "unprognostic (1.83e-1)" "unprognostic (3.37e-1)" "unprognostic (2.55e-3)" "unprognostic (7.85e-2)" "unprognostic (1.10e-1)" "unprognostic (1.26e-1)" "unprognostic (7.81e-2)" "unprognostic (3.78e-3)" "unprognostic (2.38e-1)" "unprognostic (2.74e-3)" "unprognostic (1.80e-1)" "unprognostic (3.79e-2)" "potential prognostic favorable (7.74e-4)" ETHE1 "HSCO, YF13H12" ENSG00000105755 "ETHE1 persulfide dioxygenase" O95571 19 43506719-43527230 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 239.8" "Cell type enhanced" "Detected in many" "Colonocytes: 1275.3;Enteric stem cells: 296.8;Enteric transient amplifying cells: 501.1;Enterocytes: 317.2;Esophageal apical cells: 1127.8;Goblet cells: 262.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028360, HPA029028, HPA029029" Enhanced Enhanced Mitochondria No No "Cluster 13: Non-specific - Mitochondria" "Cluster 17: Intestine - Digestion" "Cluster 19: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 5 Mitochondria "HPA028360: , HPA029028: , HPA029029: " "unprognostic (2.40e-1)" "unprognostic (1.21e-1)" "unprognostic (4.35e-2)" "unprognostic (8.60e-3)" "unprognostic (7.11e-2)" "unprognostic (1.69e-1)" "unprognostic (6.22e-2)" "unprognostic (2.07e-1)" "unprognostic (6.15e-2)" "unprognostic (7.44e-2)" "unprognostic (2.38e-2)" "unprognostic (2.17e-1)" "unprognostic (7.34e-3)" "unprognostic (2.47e-1)" "unprognostic (3.51e-2)" "unprognostic (1.13e-3)" "unprognostic (1.63e-2)" "unprognostic (2.27e-1)" "unprognostic (2.39e-2)" "unprognostic (3.04e-1)" "unprognostic (1.74e-1)" "unprognostic (2.97e-2)" "unprognostic (1.26e-2)" "unprognostic (2.16e-1)" "unprognostic (3.25e-1)" "unprognostic (4.31e-1)" "unprognostic (6.25e-2)" "unprognostic (1.45e-1)" "unprognostic (1.32e-1)" "unprognostic (1.44e-2)" "unprognostic (3.37e-1)" ETNK1 "EKI, EKI1" ENSG00000139163 "Ethanolamine kinase 1" Q9HBU6 12 22625075-22690665 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Foveolar cells: 671.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010712, HPA029407" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 42: Retina - Visual perception" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 38: Non-specific - Transcription" "Cluster 68: Foveolar cells - Mucosal defense" 6 "Nucleoplasm, Plasma membrane, Cytosol" "HPA010712: , HPA029407: " "unprognostic (3.75e-1)" "unprognostic (1.37e-1)" "unprognostic (5.14e-2)" "unprognostic (3.06e-2)" "unprognostic (4.60e-3)" "unprognostic (5.61e-3)" "unprognostic (6.27e-2)" "unprognostic (7.60e-3)" "unprognostic (3.08e-2)" "unprognostic (6.74e-2)" "unprognostic (3.08e-2)" "unprognostic (7.94e-2)" "unprognostic (9.08e-2)" "unprognostic (3.50e-3)" "unprognostic (2.52e-2)" "unprognostic (2.29e-2)" "unprognostic (1.30e-1)" "unprognostic (1.72e-2)" "unprognostic (3.24e-1)" "unprognostic (9.14e-3)" "unprognostic (1.96e-2)" "unprognostic (2.08e-1)" "unprognostic (1.70e-1)" "unprognostic (1.35e-1)" "unprognostic (1.03e-1)" "unprognostic (1.78e-2)" "unprognostic (1.23e-1)" "unprognostic (3.00e-1)" "unprognostic (2.34e-1)" "unprognostic (1.78e-1)" "unprognostic (6.72e-2)" ETNK2 "EKI2, FLJ10761" ENSG00000143845 "Ethanolamine kinase 2" Q9NVF9 1 204131062-204152044 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 100.2;liver: 219.7;testis: 118.5" "Cell type enriched" "Detected in many" 4 "Late spermatids: 2339.1" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 23.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Spleen - Fibroblasts_2, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 9 "basal ganglia: 33.9" HPA057167 Enhanced NA NA "Cluster 1: T-cells - Unknown function" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 27: Breast cancer - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 7 "HPA057167: " "unprognostic (9.23e-2)" "unprognostic (2.11e-1)" "unprognostic (3.34e-1)" "unprognostic (5.06e-2)" "unprognostic (1.09e-1)" "unprognostic (2.19e-1)" "potential prognostic unfavorable (2.13e-5)" "unprognostic (2.77e-2)" "unprognostic (1.77e-1)" "unprognostic (3.59e-3)" "potential prognostic favorable (1.91e-8)" "unprognostic (5.42e-2)" "unprognostic (7.73e-2)" "unprognostic (7.99e-3)" "unprognostic (1.47e-3)" "unprognostic (8.95e-2)" "unprognostic (1.16e-1)" "unprognostic (2.11e-1)" "unprognostic (1.17e-3)" "unprognostic (1.59e-1)" "unprognostic (5.73e-2)" "unprognostic (3.76e-2)" "potential prognostic unfavorable (3.87e-4)" "unprognostic (4.34e-2)" "unprognostic (3.83e-1)" "unprognostic (3.73e-2)" "unprognostic (1.23e-3)" "unprognostic (9.15e-3)" "unprognostic (5.15e-2)" "unprognostic (1.03e-1)" "unprognostic (2.49e-1)" ETNPPL AGXT2L1 ENSG00000164089 "Ethanolamine-phosphate phospho-lyase" Q8TBG4 4 108742048-108763054 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 264.5;liver: 178.6" "Cell type enhanced" "Detected in some" "Astrocytes: 513.6;Bergmann glia: 175.7;Hepatocytes: 34.0;Parietal cells: 118.4;Salivary acinar cells: 40.2" "Group enriched" "Detected in many" 25 "astrocyte: 542.6;Bergmann glia: 207.2" "Group enriched" "Detected in some" 21 "Glioblastoma Multiforme (TCGA): 18.2;Liver Hepatocellular Carcinoma (TCGA): 39.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "liver cancer: 1.1" "Heart muscle - Cardiomyocytes, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044546, HPA072938" Enhanced Approved Nucleoplasm Yes NA "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 28: Astrocytes - Homeostasis & neuron support" 1 Nucleoplasm "HPA044546: , HPA072938: " "unprognostic (5.74e-3)" "unprognostic (3.01e-3)" "unprognostic (9.00e-2)" "unprognostic (3.09e-3)" "unprognostic (1.16e-1)" "unprognostic (3.51e-1)" "unprognostic (2.14e-1)" ETS1 "ETS-1, EWSR2, FLJ10768" ENSG00000134954 "ETS proto-oncogene 1, transcription factor" P14921 11 128458761-128587558 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins, Transcription factors" "Immunity, Transcription, Transcription regulation" DNA-binding Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 253.0" "Cell type enhanced" "Detected in many" "B-cells: 226.5;Innate lymphoid cells: 387.5;Lymphatic endothelial cells: 248.7;Melanocytes: 278.6;NK-cells: 688.7;T-cells: 738.6;Vascular endothelial cells: 390.9" "Group enriched" "Detected in many" 5 "endothelial cell: 425.9;leukocyte: 767.2;pericyte: 441.8;vascular associated smooth muscle cell: 199.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Pancreas - Endothelial cells, Pituitary gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002575, HPA063230" Enhanced Supported Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 9: T-cells - Adaptive immunity: Regulation" 24 Nucleoplasm "CAB002575: , HPA063230: " "potential prognostic favorable (3.91e-4)" "unprognostic (4.10e-2)" "unprognostic (1.61e-2)" "unprognostic (1.24e-1)" "unprognostic (3.45e-2)" "unprognostic (3.91e-2)" "unprognostic (2.57e-1)" "unprognostic (1.89e-1)" "unprognostic (3.66e-1)" "unprognostic (3.09e-1)" "validated prognostic favorable (2.39e-6)" "validated prognostic favorable (2.44e-4)" "unprognostic (2.84e-2)" "unprognostic (2.87e-2)" "unprognostic (4.38e-2)" "unprognostic (8.56e-2)" "unprognostic (9.10e-3)" "unprognostic (9.72e-2)" "unprognostic (2.15e-2)" "unprognostic (1.01e-1)" "unprognostic (3.26e-2)" "unprognostic (5.71e-2)" "potential prognostic unfavorable (8.96e-4)" "unprognostic (1.71e-1)" "unprognostic (2.57e-1)" "unprognostic (8.31e-2)" "unprognostic (4.23e-3)" "unprognostic (9.36e-2)" "unprognostic (3.37e-2)" "unprognostic (6.00e-2)" "unprognostic (6.66e-2)" ETS2 ENSG00000157557 "ETS proto-oncogene 2, transcription factor" P15036 21 38805183-38824955 "Predicted intracellular proteins, RAS pathway related proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 811.4;Neutrophils: 1862.9;Respiratory basal cells: 658.6" "Cell type enriched" "Detected in many" 4 "endothelial cell: 528.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "dendritic cells: 33.6;granulocytes: 37.1;monocytes: 32.5" "Low cancer specificity" "Detected in all" "Colon - Neutrophils, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Spleen - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003176 Enhanced "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 77: Intestine - Digestion" "Cluster 53: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 24 Nucleoplasm "Plasma membrane, Cytosol" "HPA003176: " "unprognostic (3.47e-2)" "unprognostic (2.92e-2)" "unprognostic (2.87e-2)" "unprognostic (4.32e-2)" "unprognostic (1.15e-3)" "unprognostic (2.53e-2)" "unprognostic (1.08e-1)" "unprognostic (5.95e-3)" "unprognostic (1.07e-1)" "unprognostic (1.43e-1)" "validated prognostic favorable (5.69e-4)" "validated prognostic favorable (5.57e-5)" "unprognostic (1.19e-1)" "unprognostic (8.93e-3)" "unprognostic (5.66e-3)" "unprognostic (5.74e-2)" "unprognostic (8.11e-2)" "unprognostic (7.29e-2)" "unprognostic (1.29e-1)" "unprognostic (1.11e-2)" "unprognostic (2.60e-1)" "unprognostic (1.80e-2)" "unprognostic (7.12e-2)" "unprognostic (1.83e-1)" "unprognostic (8.48e-3)" "unprognostic (1.04e-1)" "unprognostic (1.65e-3)" "unprognostic (1.16e-1)" "unprognostic (1.18e-1)" "unprognostic (1.16e-2)" "unprognostic (8.07e-2)" ETV1 ER81 ENSG00000006468 "ETS variant transcription factor 1" P50549 7 13891229-13991425 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 124.0;salivary gland: 85.2" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 130.9;Alveolar cells type 2: 218.9;Bergmann glia: 106.6;Brain excitatory neurons: 256.6;Corticotrophs: 232.5;Neuroendocrine cells: 170.5;Oligodendrocyte progenitor cells: 260.0;Salivary acinar cells: 300.2" "Cell type enhanced" "Detected in all" "upper rhombic lip: 760.4" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 85.5" "Group enriched" "Detected in all" 4 "cerebellum: 235.6;thalamus: 74.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "prostate cancer: 72.9" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Eccrine sweat gland cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 284.0" "HPA068389, HPA077249" Supported Approved Nucleoplasm No No "Cluster 27: Cerebellum - Synaptic function" "Cluster 15: Non-specific - Transcription" "Cluster 60: Prostate cancer - Unknown function" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 12 Nucleoplasm "HPA068389: , HPA077249: " "unprognostic (2.05e-2)" "unprognostic (1.10e-1)" "unprognostic (1.10e-1)" "unprognostic (5.39e-3)" "unprognostic (2.94e-2)" "unprognostic (4.51e-2)" "unprognostic (9.17e-2)" "unprognostic (1.77e-2)" "unprognostic (7.45e-2)" "unprognostic (2.87e-2)" "unprognostic (3.57e-1)" "unprognostic (1.07e-1)" "unprognostic (1.54e-1)" "potential prognostic unfavorable (1.40e-6)" "unprognostic (9.11e-2)" "unprognostic (1.75e-2)" "unprognostic (3.51e-2)" "unprognostic (2.25e-1)" "unprognostic (3.06e-1)" "unprognostic (1.57e-2)" "potential prognostic unfavorable (1.13e-6)" "unprognostic (3.50e-1)" "unprognostic (2.95e-1)" "unprognostic (2.93e-1)" "unprognostic (2.65e-2)" "unprognostic (2.91e-2)" "unprognostic (1.67e-1)" "unprognostic (4.85e-3)" "unprognostic (2.60e-1)" "unprognostic (7.98e-2)" "unprognostic (2.73e-1)" ETV2 ER71 ENSG00000105672 "ETS variant transcription factor 2" O00321 19 35641745-35644871 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 6 "testis: 18.2" "Cell type enriched" "Detected in many" 4 "Late spermatids: 830.1" "Cell type enhanced" "Detected in some" "Bergmann glia: 3.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 6 "plasmacytoid DC: 20.8" "Lineage enriched" "Detected in many" 6 "dendritic cells: 20.8" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (other), Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 23: Testis - Spermatogenesis" "Cluster 35: Non-specific - DNA binding" "Cluster 4: Non-specific - Transcription" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 1 "unprognostic (6.77e-3)" "unprognostic (1.01e-1)" "unprognostic (1.22e-1)" "unprognostic (4.90e-2)" "unprognostic (9.53e-2)" "unprognostic (2.00e-2)" "unprognostic (1.54e-1)" "unprognostic (5.08e-2)" "unprognostic (1.69e-1)" "unprognostic (1.77e-2)" "unprognostic (1.72e-2)" "unprognostic (2.60e-2)" "unprognostic (7.02e-2)" "unprognostic (1.10e-1)" "unprognostic (6.93e-2)" "unprognostic (2.89e-1)" "unprognostic (4.31e-2)" "unprognostic (3.19e-2)" "potential prognostic favorable (8.09e-4)" "unprognostic (1.27e-1)" "unprognostic (3.38e-2)" "unprognostic (3.13e-3)" "unprognostic (5.51e-2)" "potential prognostic favorable (2.75e-4)" "unprognostic (1.84e-1)" "unprognostic (3.16e-2)" "unprognostic (1.13e-1)" ETV3 PE-1 ENSG00000117036 "ETS variant transcription factor 3" P41162 1 157121191-157138474 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "cDC: 325.2;Epididymal basal cells: 132.4;monocytes: 127.9;Ocular epithelial cells: 162.4;pDCs: 147.0;Urothelial cells: 157.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004794, HPA072144, HPA073211" Supported Approved Nucleoplasm,Nucleoli,Vesicles,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 58: Skin - Keratinization" "Cluster 7: Non-specific - Ribosome" "Cluster 45: Non-specific - Nuclear processes" "Cluster 82: Dendritic cells - Antigen presentation" 25 Nucleoplasm "Nucleoli, Vesicles, Cytosol" "HPA004794: , HPA072144: , HPA073211: " "potential prognostic favorable (5.74e-4)" "unprognostic (1.63e-1)" "unprognostic (4.14e-1)" "unprognostic (5.84e-2)" "unprognostic (2.38e-2)" "unprognostic (3.58e-1)" "unprognostic (2.38e-1)" "unprognostic (2.14e-1)" "unprognostic (7.04e-2)" "unprognostic (2.28e-2)" "potential prognostic favorable (1.89e-5)" "unprognostic (3.26e-3)" "unprognostic (8.08e-3)" "unprognostic (1.20e-2)" "unprognostic (1.68e-1)" "unprognostic (4.44e-2)" "unprognostic (3.54e-2)" "unprognostic (1.40e-1)" "unprognostic (6.87e-2)" "unprognostic (3.99e-3)" "unprognostic (1.80e-2)" "unprognostic (1.85e-3)" "unprognostic (1.55e-1)" "unprognostic (1.58e-1)" "unprognostic (3.84e-3)" "unprognostic (1.87e-1)" "unprognostic (8.95e-2)" "unprognostic (3.94e-1)" "unprognostic (9.18e-2)" "unprognostic (6.82e-3)" "unprognostic (1.61e-1)" ETV3L FLJ16478 ENSG00000253831 "ETS variant transcription factor 3 like" Q6ZN32 1 157092043-157112412 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 10 "choroid plexus: 8.7" "Cell type enhanced" "Detected in some" "Breast secretory cells: 2.4;cDC: 7.1;Gastric progenitor cells: 1.3;Gonadotrophs: 1.7;Kupffer cells: 2.0;Macrophages: 2.3;monocytes: 2.5;pDCs: 1.3;Prostatic club cells: 1.8;Prostatic hillock cells: 1.5;Thymocytes: 1.7" "Cell type enhanced" "Detected in single" "medium spiny neuron: 2.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "choroid plexus: 3.6;hypothalamus: 3.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "lymphoma: 1.0" "Pituitary gland - Gonadotropes" "Not detected" "Not detected" HPA072144 Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 82: Dendritic cells - Antigen presentation" 1 "Nucleoplasm, Nucleoli" Cytosol "HPA072144: " ETV4 "E1A-F, E1AF, PEA3" ENSG00000175832 "ETS variant transcription factor 4" P43268 17 43527844-43579620 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cholangiocytes: 33.4;Extravillous trophoblasts: 30.7;Gastric progenitor cells: 26.9;Pituitary stem cells: 36.7;Syncytiotrophoblasts: 23.4;Tuft cells: 69.2" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 202.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Colon - Enteric glia cells, Liver - Cholangiocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA005768 Approved Supported "Nucleoli rim,Mitotic chromosome" Yes No "Cluster 82: Salivary gland - Secretion" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 7 "Nucleoli rim" "Mitotic chromosome" "HPA005768: " "potential prognostic unfavorable (4.30e-4)" "unprognostic (1.46e-1)" "unprognostic (3.31e-1)" "unprognostic (1.20e-2)" "unprognostic (1.63e-1)" "unprognostic (4.74e-2)" "unprognostic (3.35e-2)" "potential prognostic unfavorable (9.92e-4)" "unprognostic (2.73e-3)" "unprognostic (2.47e-1)" "unprognostic (2.13e-2)" "potential prognostic unfavorable (7.48e-5)" "unprognostic (4.49e-3)" "unprognostic (6.11e-2)" "unprognostic (1.45e-1)" "unprognostic (1.53e-1)" "unprognostic (3.69e-2)" "unprognostic (1.82e-1)" "unprognostic (4.17e-1)" "unprognostic (9.37e-2)" "unprognostic (1.52e-1)" "unprognostic (2.03e-1)" "unprognostic (1.96e-2)" "unprognostic (3.24e-1)" "unprognostic (2.15e-1)" "unprognostic (2.84e-1)" "unprognostic (1.69e-1)" "unprognostic (3.88e-2)" "unprognostic (4.45e-2)" ETV5 ERM ENSG00000244405 "ETS variant transcription factor 5" P41161 3 186046314-186110318 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 146.5;Bergmann glia: 174.2;Hofbauer cells: 127.4;Kupffer cells: 219.3;Microglia: 229.5;Mucous neck cells: 140.5;Oligodendrocyte progenitor cells: 194.0;Pituitary stem cells: 174.6;Syncytiotrophoblasts: 129.4" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 275.6" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 110.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "skin cancer: 100.7" "Lung - Alveolar cells type 2, Spleen - Macrophages, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009590, HPA063065, HPA073889" Approved Supported Nucleoplasm NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 51: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 3 Nucleoplasm "CAB009590: , HPA063065: , HPA073889: " "unprognostic (9.61e-2)" "unprognostic (3.75e-1)" "unprognostic (4.59e-2)" "unprognostic (1.00e-2)" "unprognostic (1.51e-2)" "potential prognostic unfavorable (2.17e-5)" "unprognostic (1.92e-1)" "unprognostic (2.05e-2)" "unprognostic (5.12e-2)" "unprognostic (2.08e-2)" "unprognostic (1.18e-3)" "unprognostic (3.12e-1)" "unprognostic (5.27e-2)" "potential prognostic unfavorable (8.67e-10)" "unprognostic (2.52e-2)" "unprognostic (5.53e-2)" "unprognostic (5.52e-2)" "unprognostic (9.28e-2)" "potential prognostic favorable (7.38e-4)" "unprognostic (2.02e-1)" "unprognostic (3.40e-2)" "unprognostic (3.47e-2)" "unprognostic (3.98e-2)" "unprognostic (3.17e-1)" "unprognostic (7.60e-3)" "unprognostic (1.30e-1)" "unprognostic (1.32e-1)" "unprognostic (1.59e-1)" "unprognostic (1.70e-1)" "unprognostic (2.75e-2)" "unprognostic (4.60e-2)" ETV6 TEL ENSG00000139083 "ETS variant transcription factor 6" P41212 12 11649674-11895377 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hematopoietic stem cells: 1563.4;Lacrimal acinar cells: 1322.5;Neutrophils: 1149.1;Thymocytes: 1200.1" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 987.8;vascular associated smooth muscle cell: 738.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Liver - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000264 Enhanced Approved Nucleoli,Cytosol NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 44: Non-specific - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 51: Secretory epithelial cells - Mixed function" 26 Nucleoli Cytosol "HPA000264: " "potential prognostic favorable (5.26e-4)" "unprognostic (1.99e-2)" "potential prognostic favorable (7.75e-4)" "unprognostic (2.23e-1)" "unprognostic (1.14e-1)" "unprognostic (1.10e-1)" "unprognostic (2.53e-1)" "unprognostic (1.44e-1)" "unprognostic (1.87e-2)" "unprognostic (1.30e-3)" "potential prognostic unfavorable (4.64e-5)" "unprognostic (1.59e-1)" "unprognostic (1.79e-1)" "unprognostic (7.12e-2)" "unprognostic (3.90e-2)" "unprognostic (2.57e-1)" "unprognostic (1.34e-2)" "unprognostic (8.87e-2)" "unprognostic (5.51e-2)" "unprognostic (4.38e-3)" "unprognostic (4.49e-2)" "potential prognostic unfavorable (7.53e-4)" "unprognostic (1.96e-2)" "unprognostic (1.52e-1)" "unprognostic (2.27e-1)" "unprognostic (1.75e-1)" "unprognostic (2.25e-1)" "unprognostic (1.19e-2)" "unprognostic (6.22e-2)" "unprognostic (1.56e-1)" "unprognostic (8.17e-2)" ETV7 "TEL-2, TEL2" ENSG00000010030 "ETS variant transcription factor 7" Q9Y603 6 36354091-36387800 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 15.0;skin 1: 14.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 37.5;Differentiating spermatogonia: 62.8;Early primary spermatocytes: 17.1;Enterocytes: 20.7;Epicardial cells: 20.5;Esophageal basal cells: 16.5;Migrating cytotrophoblasts: 23.9;Tuft cells: 34.6" "Group enriched" "Detected in some" 4 "pericyte: 12.4;vascular associated smooth muscle cell: 13.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 18.9;T-reg: 16.4" "Group enriched" "Detected in many" 4 "granulocytes: 18.9;monocytes: 5.7;T-cells: 16.4" "Low cancer specificity" "Detected in many" "Breast - T-cells, Skin - Keratinocyte (granular), Thyroid gland - T-cells" "Low region specificity" "Detected in all" HPA029033 Uncertain Supported Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 77: Intestine - Digestion" "Cluster 8: Immune cells - Immune response" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 7 Nucleoplasm "HPA029033: " "unprognostic (3.34e-2)" "unprognostic (1.10e-2)" "unprognostic (3.88e-2)" "unprognostic (3.56e-2)" "unprognostic (1.42e-1)" "unprognostic (3.20e-1)" "unprognostic (2.90e-1)" "potential prognostic unfavorable (9.04e-4)" "potential prognostic favorable (2.44e-4)" "unprognostic (5.38e-2)" "unprognostic (1.07e-1)" "unprognostic (1.16e-1)" "unprognostic (4.24e-2)" "unprognostic (1.12e-1)" "unprognostic (4.67e-2)" "unprognostic (1.52e-1)" "unprognostic (3.07e-2)" "unprognostic (9.52e-2)" "unprognostic (5.29e-2)" "unprognostic (3.72e-3)" "potential prognostic favorable (4.23e-4)" "unprognostic (2.24e-3)" "unprognostic (3.15e-1)" "unprognostic (2.28e-1)" "unprognostic (1.80e-2)" "unprognostic (1.60e-2)" "unprognostic (2.49e-2)" "unprognostic (6.30e-3)" "unprognostic (4.97e-1)" "unprognostic (4.24e-3)" "unprognostic (1.25e-2)" EVA1A "FAM176A, FLJ13391, TMEM166" ENSG00000115363 "Eva-1 homolog A, regulator of programmed cell death" Q9H8M9 2 75469302-75569722 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Autophagy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "liver: 178.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 85.2;Alveolar cells type 2: 70.8;Cytotrophoblasts: 71.8;Hepatocytes: 99.1;Melanocytes: 56.6;Pancreatic acinar cells: 83.9;Pancreatic islet cells: 63.1;Proximal tubule cells: 201.0;Syncytiotrophoblasts: 208.5" "Cell type enhanced" "Detected in all" "endothelial cell: 21.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 81.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008055 Approved Supported "Vesicles,Plasma membrane" NA Yes "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 43: Hindbrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 88: Proximal tubular cells - Transmembrane transport" 5 Vesicles "Plasma membrane" "HPA008055: " "potential prognostic unfavorable (6.68e-4)" "unprognostic (1.87e-1)" "unprognostic (2.24e-2)" "unprognostic (6.40e-2)" "unprognostic (4.21e-2)" "potential prognostic unfavorable (2.24e-4)" "unprognostic (2.27e-2)" "unprognostic (1.23e-2)" "unprognostic (4.26e-1)" "potential prognostic favorable (2.96e-6)" "unprognostic (1.98e-2)" "unprognostic (5.27e-2)" "unprognostic (8.84e-3)" "potential prognostic favorable (4.08e-4)" "unprognostic (1.93e-2)" "unprognostic (3.26e-3)" "unprognostic (1.59e-2)" "unprognostic (1.38e-2)" "unprognostic (2.74e-1)" "unprognostic (1.84e-2)" "unprognostic (1.14e-2)" "unprognostic (1.66e-1)" "unprognostic (2.46e-1)" "unprognostic (5.64e-2)" "unprognostic (6.76e-3)" "unprognostic (2.32e-2)" "unprognostic (9.97e-3)" "unprognostic (2.65e-1)" EVA1B "C1orf78, FAM176B, FLJ10647" ENSG00000142694 "Eva-1 homolog B" Q9NVM1 1 36322030-36324154 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 228.3;Breast lactating cells: 204.2;Extravillous trophoblasts: 363.5;Megakaryocytes: 136.0;Platelets: 214.0;Syncytiotrophoblasts: 190.7" "Group enriched" "Detected in some" 4 "endothelial cell: 45.1;fibroblast: 44.3;pericyte: 112.9;vascular associated smooth muscle cell: 33.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 4.3" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA041928, HPA043537" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 44: Non-specific - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 19 "Plasma membrane" "Nucleoplasm, Cytosol" "HPA041928: , HPA043537: " "unprognostic (2.73e-1)" "unprognostic (1.32e-3)" "unprognostic (9.40e-2)" "unprognostic (3.62e-3)" "unprognostic (5.95e-2)" "unprognostic (5.44e-2)" "unprognostic (2.51e-2)" "unprognostic (1.39e-1)" "unprognostic (1.32e-1)" "unprognostic (2.23e-1)" "unprognostic (9.48e-2)" "unprognostic (1.67e-1)" "potential prognostic unfavorable (4.27e-4)" "unprognostic (2.99e-2)" "unprognostic (2.06e-1)" "unprognostic (2.15e-1)" "unprognostic (2.45e-2)" "unprognostic (4.01e-2)" "unprognostic (3.84e-2)" "unprognostic (1.35e-1)" "unprognostic (1.22e-2)" "unprognostic (1.48e-2)" "unprognostic (6.21e-2)" "unprognostic (5.21e-3)" "unprognostic (4.31e-2)" "unprognostic (1.00e-1)" "unprognostic (1.05e-1)" EVA1C "B18, B19, C21orf63, C21orf64, FAM176C, PRED34" ENSG00000166979 "Eva-1 homolog C" P58658 21 32412006-32515397 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late spermatids: 412.9;Respiratory ciliated cells: 420.4;Respiratory secretory cells: 410.2;Vascular endothelial cells: 442.6" "Cell type enhanced" "Detected in all" "endothelial cell: 373.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 1.1;gdT-cell: 3.1;MAIT T-cell: 3.8;memory CD4 T-cell: 3.2;memory CD8 T-cell: 3.2;naive CD8 T-cell: 1.6;NK-cell: 3.2" "Group enriched" "Detected in many" 7 "granulocytes: 1.1;NK-cells: 3.2;T-cells: 3.8" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015720, HPA029944, CAB034174, HPA076996" Enhanced Approved Cytosol NA NA "Cluster 1: T-cells - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 6: Non-specific - Immune response" "Cluster 7: Liver cancer - Metabolism" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" Cytosol "CAB034174: , HPA015720: , HPA029944: , HPA076996: " "unprognostic (7.72e-2)" "unprognostic (1.25e-2)" "unprognostic (2.58e-2)" "unprognostic (8.35e-2)" "unprognostic (1.53e-1)" "unprognostic (2.11e-2)" "potential prognostic unfavorable (2.02e-6)" "potential prognostic favorable (5.17e-4)" "potential prognostic favorable (5.60e-5)" "unprognostic (1.75e-3)" "unprognostic (5.17e-3)" "unprognostic (2.03e-3)" "unprognostic (2.65e-1)" "unprognostic (9.33e-2)" "unprognostic (5.21e-3)" "unprognostic (3.74e-2)" "unprognostic (8.35e-3)" "unprognostic (5.70e-2)" "unprognostic (3.46e-2)" "unprognostic (3.31e-2)" "unprognostic (1.49e-1)" "unprognostic (1.37e-1)" "unprognostic (1.24e-2)" "unprognostic (1.82e-1)" "unprognostic (2.06e-2)" "unprognostic (1.79e-1)" "unprognostic (2.73e-2)" "unprognostic (4.52e-2)" EVC "DWF-1, EVC1" ENSG00000072840 "EvC ciliary complex subunit 1" P57679 4 5711201-5814305 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Ciliopathy, Disease variant, Dwarfism, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 71.4;Fibro-adipogenic progenitors: 73.0;Loop of henle epithelial cells: 216.8;Myosatellite cells: 97.2;Proximal tubule cells: 162.8;Renal collecting duct intercalated cells: 60.1" "Cell type enhanced" "Detected in many" "astrocyte: 30.8;fibroblast: 41.7" "Cancer enhanced" "Detected in all" "Kidney Renal Papillary Cell Carcinoma (TCGA): 52.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008703, HPA016046" Uncertain Approved "Nucleoplasm,Primary cilium,Basal body,Cytosol" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 44: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" "Nucleoplasm, Basal body" "Primary cilium, Cytosol" "HPA008703: , HPA016046: " "unprognostic (4.70e-2)" "unprognostic (2.09e-1)" "unprognostic (2.10e-2)" "unprognostic (3.19e-3)" "unprognostic (5.50e-2)" "unprognostic (3.32e-1)" "unprognostic (4.70e-2)" "potential prognostic unfavorable (5.56e-6)" "unprognostic (1.48e-1)" "unprognostic (3.41e-1)" "validated prognostic favorable (4.86e-9)" "validated prognostic favorable (9.99e-4)" "unprognostic (1.44e-3)" "unprognostic (6.16e-2)" "unprognostic (7.76e-2)" "unprognostic (3.22e-1)" "unprognostic (6.01e-3)" "unprognostic (7.47e-2)" "unprognostic (2.18e-1)" "unprognostic (1.01e-2)" "unprognostic (6.41e-3)" "unprognostic (5.22e-2)" "unprognostic (1.25e-1)" "unprognostic (3.99e-1)" "unprognostic (2.89e-1)" "unprognostic (1.13e-3)" "unprognostic (1.26e-1)" "unprognostic (4.79e-2)" "unprognostic (9.36e-2)" "unprognostic (1.19e-2)" "unprognostic (4.45e-1)" EVC2 LBN ENSG00000173040 "EvC ciliary complex subunit 2" Q86UK5 4 5542772-5709548 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Ciliopathy, Disease variant, Dwarfism, Ectodermal dysplasia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibro-adipogenic progenitors: 109.6;Leydig cells: 56.6;Loop of henle epithelial cells: 58.1;Mesothelial cells: 56.9;Myosatellite cells: 61.3;Proximal tubule cells: 58.9;Renal collecting duct intercalated cells: 57.7" "Group enriched" "Detected in many" 4 "astrocyte: 30.2;Bergmann glia: 19.8;choroid plexus epithelial cell: 15.4;ependymal cell: 34.7;fibroblast: 57.2;pericyte: 22.7;vascular associated smooth muscle cell: 23.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Heart muscle - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040910, HPA048122" Uncertain Approved "Nucleoplasm,Plasma membrane,Microtubules,Cytokinetic bridge,Primary cilium,Primary cilium tip,Basal body,Cytosol" Yes NA "Cluster 75: Ovary - Mixed function" "Cluster 3: Choroid plexus - Cilium" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" "Plasma membrane, Microtubules, Cytokinetic bridge, Primary cilium" "Nucleoplasm, Primary cilium tip, Basal body, Cytosol" "HPA040910: , HPA048122: " "unprognostic (1.41e-1)" "unprognostic (8.81e-2)" "unprognostic (3.66e-1)" "unprognostic (4.30e-2)" "unprognostic (2.30e-2)" "unprognostic (8.63e-3)" "potential prognostic unfavorable (7.11e-6)" "unprognostic (2.85e-1)" "unprognostic (1.86e-2)" "potential prognostic favorable (6.40e-6)" "unprognostic (2.44e-2)" "unprognostic (5.64e-2)" "unprognostic (3.32e-2)" "unprognostic (1.45e-2)" "unprognostic (3.59e-2)" "unprognostic (1.16e-1)" "unprognostic (1.38e-1)" "unprognostic (3.88e-2)" "unprognostic (1.93e-1)" "unprognostic (3.09e-2)" "unprognostic (1.50e-1)" "unprognostic (1.19e-1)" "unprognostic (2.87e-2)" "unprognostic (1.87e-1)" "unprognostic (1.43e-1)" "unprognostic (1.35e-1)" "unprognostic (9.91e-2)" EVI2A "EVDA, EVI2" ENSG00000126860 "Ecotropic viral integration site 2A" P22794 17 31316410-31321749 "Predicted membrane proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 164.5;lymphoid tissue: 97.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 45.3;cDC: 15.9;Epicardial cells: 22.7;Innate lymphoid cells: 18.8;Kupffer cells: 18.4;Macrophages: 18.0;Mast cells: 17.8;Microglia: 19.4;Monocyte progenitors: 17.0;monocytes: 24.6;Neutrophils: 68.7;NK-cells: 26.1;Oligodendrocytes: 74.3;Plasma cells: 23.7;T-cells: 27.0" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 24.2;oligodendrocyte: 95.4" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 35.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 30.0;Myeloma: 68.8" "Adipose subcutaneous - Macrophages, Adrenal gland - Macrophages, Minor Salivary Gland - Macrophages, Skeletal muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045033 Uncertain Supported "Golgi apparatus,Vesicles,Plasma membrane,Primary cilium,Primary cilium transition zone,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 9: T-cells - Adaptive immunity: Regulation" 8 "Golgi apparatus, Vesicles, Plasma membrane, Primary cilium" "Primary cilium transition zone, Cytosol" "HPA045033: " "unprognostic (3.34e-1)" "unprognostic (1.21e-1)" "unprognostic (2.23e-1)" "unprognostic (1.44e-2)" "unprognostic (1.29e-1)" "unprognostic (2.22e-1)" "unprognostic (1.24e-1)" "unprognostic (1.87e-1)" "unprognostic (6.70e-2)" "unprognostic (2.86e-1)" "unprognostic (4.76e-2)" "unprognostic (1.82e-1)" "unprognostic (2.34e-1)" "unprognostic (1.23e-1)" "unprognostic (1.59e-1)" "unprognostic (1.71e-2)" "unprognostic (8.55e-2)" "unprognostic (1.94e-2)" "unprognostic (1.54e-1)" "unprognostic (1.34e-1)" "unprognostic (1.09e-2)" "unprognostic (7.14e-2)" "unprognostic (9.03e-2)" "unprognostic (2.05e-2)" "unprognostic (7.12e-2)" "unprognostic (2.06e-1)" "unprognostic (1.89e-3)" "unprognostic (6.39e-2)" "unprognostic (3.45e-2)" "unprognostic (3.35e-2)" "unprognostic (6.49e-2)" EVI2B "CD361, D17S376, EVDB" ENSG00000185862 "Ecotropic viral integration site 2B" P34910 17 31303770-31314105 "CD markers, Predicted membrane proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 178.5;lymphoid tissue: 159.2" "Cell type enhanced" "Detected in many" "B-cells: 166.7;cDC: 178.9;Kupffer cells: 470.4;Macrophages: 188.4;Monocyte progenitors: 209.5;monocytes: 449.3;Neutrophil progenitors: 349.6;Neutrophils: 1773.9;Plasma cells: 184.7" "Group enriched" "Detected in some" 6 "central nervous system macrophage: 61.1;leukocyte: 58.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1371.1" "Group enriched" "Detected in all" 5 "granulocytes: 1371.1;monocytes: 383.9" "Group enriched" "Detected in many" 11 "Adrenocortical cancer: 21.0;Leukemia: 50.5;lymphoma: 45.6;Myeloma: 68.3" "Adipose subcutaneous - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Heart muscle - Macrophages, Lung - Neutrophils_2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA007346, HPA053383" Enhanced Approved "Plasma membrane" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 30: White matter - Myelination" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" "Plasma membrane" "HPA007346: , HPA053383: " "unprognostic (5.10e-2)" "unprognostic (1.47e-2)" "unprognostic (1.43e-1)" "unprognostic (1.18e-1)" "unprognostic (1.76e-1)" "unprognostic (3.31e-1)" "unprognostic (8.15e-2)" "unprognostic (2.59e-1)" "unprognostic (1.75e-2)" "unprognostic (2.97e-1)" "unprognostic (6.74e-2)" "unprognostic (6.11e-2)" "unprognostic (1.96e-1)" "unprognostic (1.26e-1)" "unprognostic (5.37e-2)" "unprognostic (2.85e-3)" "unprognostic (2.00e-1)" "unprognostic (1.73e-1)" "unprognostic (2.83e-1)" "unprognostic (3.08e-1)" "unprognostic (5.88e-2)" "unprognostic (5.96e-2)" "unprognostic (3.01e-2)" "unprognostic (1.36e-1)" "unprognostic (1.18e-1)" "unprognostic (1.43e-1)" "unprognostic (3.33e-2)" "unprognostic (1.67e-2)" "unprognostic (4.39e-2)" "unprognostic (1.24e-1)" "unprognostic (3.37e-1)" EVI5 NB4S ENSG00000067208 "Ecotropic viral integration site 5" O60447 1 92508696-92792404 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Choroid plexus epithelial cells: 693.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027339 Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 46: Brainstem - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 32 "Golgi apparatus" Vesicles "HPA027339: " "unprognostic (2.45e-1)" "unprognostic (2.58e-1)" "unprognostic (1.30e-1)" "unprognostic (7.74e-2)" "potential prognostic favorable (5.30e-4)" "unprognostic (5.98e-3)" "unprognostic (1.83e-2)" "unprognostic (6.35e-2)" "unprognostic (4.85e-3)" "unprognostic (5.33e-3)" "unprognostic (1.02e-3)" "potential prognostic favorable (7.21e-4)" "unprognostic (2.50e-1)" "unprognostic (1.86e-2)" "unprognostic (1.28e-1)" "unprognostic (1.36e-1)" "unprognostic (3.29e-1)" "unprognostic (1.42e-1)" "unprognostic (2.39e-1)" "unprognostic (1.23e-1)" "unprognostic (1.60e-2)" "unprognostic (6.59e-3)" "unprognostic (4.58e-1)" "unprognostic (1.80e-1)" "unprognostic (5.14e-2)" "unprognostic (3.76e-1)" "unprognostic (2.62e-1)" "unprognostic (1.14e-1)" "unprognostic (1.26e-1)" "unprognostic (1.44e-1)" "unprognostic (9.08e-2)" EVI5L ENSG00000142459 "Ecotropic viral integration site 5 like" Q96CN4 19 7830218-7864976 "Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 41.4" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 102.1;Oligodendrocyte progenitor cells: 85.5;Oligodendrocytes: 92.8;Retinal amacrine cells: 72.9;Retinal horizontal cells: 70.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.2" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043099 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 23: Non-specific - Transcription" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 13 Nucleoplasm "Golgi apparatus, Cytosol" "HPA043099: " "unprognostic (9.77e-2)" "unprognostic (1.58e-2)" "unprognostic (1.27e-1)" "unprognostic (3.79e-2)" "unprognostic (2.11e-1)" "unprognostic (1.19e-1)" "unprognostic (2.74e-1)" "unprognostic (3.45e-3)" "unprognostic (2.33e-2)" "unprognostic (1.86e-1)" "unprognostic (1.56e-2)" "unprognostic (1.91e-1)" "unprognostic (4.06e-3)" "unprognostic (1.85e-2)" "unprognostic (1.19e-1)" "unprognostic (9.03e-2)" "unprognostic (6.17e-2)" "unprognostic (2.86e-1)" "unprognostic (2.53e-1)" "unprognostic (2.75e-1)" "unprognostic (3.17e-2)" "unprognostic (2.61e-2)" "unprognostic (2.80e-1)" "unprognostic (6.18e-2)" "unprognostic (2.14e-3)" "unprognostic (5.10e-2)" "unprognostic (1.73e-1)" "unprognostic (8.83e-2)" "unprognostic (7.24e-2)" "unprognostic (1.07e-1)" "unprognostic (1.81e-1)" EVL RNB6 ENSG00000196405 Enah/Vasp-like Q9UI08 14 99971449-100144236 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 476.1;NK-cells: 433.1;Rod photoreceptor cells: 828.2;T-cells: 473.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Leukemia: 149.1" "Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018849, HPA019536, CAB033987" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" 21 "Vesicles, Cytosol" "CAB033987: , HPA018849: , HPA019536: " "unprognostic (4.75e-2)" "unprognostic (3.83e-3)" "unprognostic (3.60e-1)" "unprognostic (2.76e-2)" "unprognostic (8.27e-2)" "unprognostic (1.71e-1)" "unprognostic (4.13e-1)" "potential prognostic favorable (3.26e-5)" "unprognostic (1.73e-2)" "unprognostic (1.61e-1)" "unprognostic (3.99e-2)" "unprognostic (1.11e-2)" "potential prognostic favorable (8.18e-4)" "unprognostic (2.40e-2)" "unprognostic (1.42e-2)" "unprognostic (7.38e-2)" "unprognostic (1.14e-1)" "unprognostic (9.19e-2)" "unprognostic (1.70e-3)" "unprognostic (2.10e-1)" "unprognostic (9.03e-2)" "potential prognostic favorable (7.55e-5)" "unprognostic (4.16e-2)" "unprognostic (1.54e-2)" "unprognostic (2.03e-1)" "unprognostic (8.24e-2)" "unprognostic (9.05e-2)" "unprognostic (5.18e-2)" "unprognostic (2.99e-1)" "potential prognostic unfavorable (8.40e-4)" "unprognostic (1.99e-1)" EVPL EVPK ENSG00000167880 Envoplakin Q92817 17 76004502-76027306 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 90.8;esophagus: 289.2;skin 1: 148.1;vagina: 102.1" "Group enriched" "Detected in many" 4 "Esophageal apical cells: 1222.7;Esophageal suprabasal cells: 348.3" "Group enriched" "Detected in some" 6 "choroid plexus epithelial cell: 2.6;lower rhombic lip: 4.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Mast cells, Adipose visceral - Mesothelial cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in many" "Region enhanced" "Detected in single" "spinal cord: 1.4" "CAB002220, HPA053969" Enhanced Supported "Intermediate filaments,Cytosol" NA NA 93000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 22 "Intermediate filaments" Cytosol "CAB002220: , HPA053969: " "unprognostic (1.32e-2)" "unprognostic (1.11e-1)" "unprognostic (5.63e-2)" "unprognostic (1.61e-1)" "unprognostic (2.30e-1)" "unprognostic (8.39e-2)" "unprognostic (2.04e-2)" "unprognostic (7.82e-2)" "unprognostic (9.58e-3)" "unprognostic (1.21e-1)" "unprognostic (3.81e-2)" "unprognostic (1.39e-1)" "unprognostic (1.30e-3)" "unprognostic (2.45e-1)" "unprognostic (1.20e-1)" "unprognostic (1.74e-1)" "unprognostic (5.52e-2)" "unprognostic (9.22e-2)" "unprognostic (1.61e-2)" "unprognostic (1.15e-2)" "unprognostic (5.75e-2)" "unprognostic (2.02e-2)" "unprognostic (9.37e-2)" "unprognostic (1.29e-1)" "unprognostic (1.94e-1)" "unprognostic (1.97e-1)" "unprognostic (7.65e-2)" "unprognostic (1.11e-1)" "unprognostic (6.79e-2)" EVPLL ENSG00000214860 "Envoplakin like" A8MZ36 17 18377778-18389647 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 7.3;esophagus: 17.1;skin 1: 6.0;vagina: 8.6" "Cell type enhanced" "Detected in some" "Loop of henle epithelial cells: 1.7;Papillary tip epithelial cells: 11.3;Proximal tubule cells: 1.8;Renal collecting duct intercalated cells: 1.3;Renal collecting duct principal cells: 6.7;Renal connecting tubule cells: 2.9" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 1.3;Esophageal cancer: 1.6" "Prostate - Urothelial cells" HPA045728 Uncertain Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 7: Liver cancer - Metabolism" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" "Nucleoplasm, Nuclear bodies" "HPA045728: " "unprognostic (4.26e-1)" "unprognostic (2.27e-1)" "unprognostic (2.94e-2)" "potential prognostic favorable (9.04e-6)" "potential prognostic favorable (3.32e-4)" "unprognostic (7.37e-2)" "unprognostic (4.46e-2)" "unprognostic (1.60e-1)" EVX1 ENSG00000106038 "Even-skipped homeobox 1" P49640 7 27242700-27250493 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 2.8;prostate: 3.8;seminal vesicle: 2.8;urinary bladder: 2.8;vagina: 3.4" "Group enriched" "Detected in some" 5 "Early spermatids: 76.4;Late spermatids: 109.8" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder Urothelial Carcinoma (TCGA): 4.9;Testicular Germ Cell Tumor (TCGA): 4.9" "Region enhanced" "Detected in some" "medulla oblongata: 3.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "colorectal cancer: 7.2;Gastric cancer: 1.9" "Kidney - Podocytes, Testis - Late spermatids" "Region enhanced" "Detected in single" "pons and medulla: 1.0" "Region enhanced" "Detected in single" "medulla oblongata: 1.4" HPA055132 Approved Nucleoplasm NA NA "Cluster 75: Ovary - Mixed function" "Cluster 43: Hindbrain - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" Nucleoplasm "HPA055132: " "unprognostic (3.84e-2)" "unprognostic (4.53e-1)" "unprognostic (2.83e-2)" "unprognostic (1.37e-1)" "unprognostic (4.02e-1)" "unprognostic (1.50e-3)" "unprognostic (1.86e-1)" "unprognostic (1.14e-1)" EVX2 ENSG00000174279 "Even-skipped homeobox 2" Q03828 2 176077472-176083962 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "prostate: 1.2;seminal vesicle: 1.5;testis: 2.8;vagina: 1.0" "Group enriched" "Detected in some" 5 "Early spermatids: 14.1;Late spermatids: 7.4" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in some" "pons: 2.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Neuroblastoma: 1.1" "Testis - Early spermatids, Testis - Late spermatids" "Group enriched" "Detected in some" 13 "midbrain: 1.3;pons and medulla: 1.1" "Not detected" "Not detected" HPA041576 Uncertain NA NA "Cluster 21: Testis - Mixed function" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 7 "HPA041576: " EWSR1 EWS ENSG00000182944 "EWS RNA binding protein 1" Q01844 22 29268009-29300525 "Cancer-related genes, Disease related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Calmodulin-binding, Repressor, RNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004230, HPA051771, HPA062953" Enhanced Supported Nucleoplasm,Nucleoli No No 21000 "Cluster 40: Monocytes - Innate immune response" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 16: Non-specific - Transcription" "Cluster 66: Non-specific - Mitochondria" "Cluster 17: Non-specific - RNA processing" 138 Nucleoplasm Nucleoli "CAB004230: , HPA051771: , HPA062953: " "unprognostic (3.29e-2)" "unprognostic (1.81e-1)" "unprognostic (1.89e-1)" "unprognostic (2.13e-2)" "unprognostic (1.44e-1)" "unprognostic (3.97e-1)" "unprognostic (2.22e-1)" "unprognostic (2.63e-1)" "unprognostic (8.70e-3)" "unprognostic (4.28e-2)" "unprognostic (2.78e-3)" "unprognostic (3.34e-2)" "unprognostic (5.11e-2)" "potential prognostic unfavorable (6.65e-8)" "unprognostic (3.15e-2)" "unprognostic (2.76e-2)" "potential prognostic unfavorable (2.64e-4)" "unprognostic (1.66e-2)" "potential prognostic favorable (4.53e-4)" "unprognostic (9.50e-2)" "unprognostic (1.82e-2)" "unprognostic (3.66e-2)" "unprognostic (9.05e-2)" "unprognostic (8.11e-2)" "unprognostic (2.44e-2)" "unprognostic (4.68e-2)" "unprognostic (7.79e-2)" "unprognostic (4.16e-2)" "unprognostic (2.57e-1)" "unprognostic (1.85e-1)" "unprognostic (3.31e-2)" EXD1 "EXDL1, MGC33637" ENSG00000178997 "Exonuclease 3'-5' domain containing 1" Q8NHP7 15 41182725-41230757 "Predicted intracellular proteins" "Meiosis, RNA-mediated gene silencing" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 30 "testis: 11.7" "Group enriched" "Detected in some" 4 "Early primary spermatocytes: 50.5;Late primary spermatocytes: 58.0" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Region enriched" "Detected in single" 4 "pons: 3.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 1 "unprognostic (5.13e-2)" EXD2 "C14orf114, EXDL2, FLJ10738" ENSG00000081177 "Exonuclease 3'-5' domain containing 2" Q9NVH0 14 69191498-69244020 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 79.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002906, HPA005848" Uncertain Approved "Intermediate filaments,Mitochondria" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 13 Mitochondria "Intermediate filaments" "HPA002906: , HPA005848: " "unprognostic (3.41e-2)" "unprognostic (2.27e-1)" "unprognostic (1.01e-1)" "unprognostic (1.16e-1)" "unprognostic (2.70e-1)" "unprognostic (8.35e-2)" "unprognostic (1.84e-1)" "unprognostic (1.41e-1)" "unprognostic (2.31e-1)" "unprognostic (2.19e-3)" "potential prognostic favorable (2.43e-7)" "unprognostic (2.03e-2)" "unprognostic (1.10e-2)" "unprognostic (6.73e-3)" "unprognostic (4.50e-2)" "unprognostic (6.08e-2)" "unprognostic (2.04e-1)" "unprognostic (2.84e-2)" "unprognostic (3.87e-2)" "unprognostic (1.67e-1)" "unprognostic (1.50e-3)" "unprognostic (1.15e-1)" "unprognostic (2.00e-1)" "unprognostic (1.19e-1)" "unprognostic (2.02e-2)" "unprognostic (1.32e-1)" "unprognostic (3.30e-1)" "unprognostic (6.83e-2)" "unprognostic (1.79e-1)" "unprognostic (4.31e-2)" "unprognostic (1.88e-2)" EXD3 "FLJ20433, LOC54932, mut-7, Nbr" ENSG00000187609 "Exonuclease 3'-5' domain containing 3" Q8N9H8 9 137306896-137423211 "Predicted intracellular proteins" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late spermatids: 123.9;Paneth cells: 119.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" HPA047395 Approved Approved "Actin filaments,Focal adhesion sites" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 64: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 1 "Focal adhesion sites" "Actin filaments" "HPA047395: " "unprognostic (4.77e-2)" "unprognostic (1.07e-1)" "unprognostic (1.62e-1)" "unprognostic (2.41e-1)" "unprognostic (6.22e-2)" "unprognostic (2.36e-2)" "unprognostic (1.91e-1)" "unprognostic (3.57e-3)" "unprognostic (4.84e-2)" "unprognostic (5.18e-2)" "unprognostic (2.63e-1)" "unprognostic (7.06e-2)" "unprognostic (2.64e-1)" "unprognostic (3.47e-3)" "potential prognostic favorable (9.32e-4)" "unprognostic (6.21e-2)" "unprognostic (3.34e-1)" "unprognostic (3.65e-1)" "unprognostic (6.00e-2)" "unprognostic (1.28e-1)" "unprognostic (2.79e-2)" "unprognostic (1.57e-2)" "unprognostic (7.65e-2)" "unprognostic (1.37e-2)" "unprognostic (1.64e-1)" "unprognostic (1.79e-1)" "unprognostic (5.40e-2)" "unprognostic (3.34e-2)" "unprognostic (1.66e-1)" "unprognostic (2.30e-1)" "unprognostic (6.02e-2)" EXO1 "HEX1, hExoI" ENSG00000174371 "Exonuclease 1" Q9UQ84 1 241847967-241895148 "Predicted intracellular proteins" "DNA damage, DNA excision, DNA repair, Immunity, Meiosis" "DNA-binding, Endonuclease, Excision nuclease, Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 16.4;lymphoid tissue: 10.3" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 24.6;Early primary spermatocytes: 18.2;Erythrocyte progenitors: 64.2;Extravillous trophoblasts: 35.1;Late primary spermatocytes: 14.5;Megakaryocyte progenitors: 33.8;Megakaryocytes: 18.5;Migrating cytotrophoblasts: 26.5;Monocyte progenitors: 40.7;Neutrophil progenitors: 17.6;Undifferentiated spermatogonia: 14.1" "Cell type enriched" "Detected in some" 4 "CGE interneuron: 7.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA053079, HPA069738" Enhanced "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 5: Non-specific - Cell proliferation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 53: Neurons - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 38 Nucleoplasm "Nuclear bodies" "HPA053079: , HPA069738: " "unprognostic (7.63e-2)" "unprognostic (2.82e-2)" "unprognostic (5.63e-2)" "unprognostic (6.79e-2)" "unprognostic (2.18e-2)" "unprognostic (4.39e-2)" "unprognostic (1.66e-1)" "unprognostic (9.04e-2)" "unprognostic (9.06e-2)" "validated prognostic unfavorable (1.55e-4)" "validated prognostic unfavorable (6.77e-5)" "potential prognostic unfavorable (1.27e-9)" "validated prognostic unfavorable (1.01e-5)" "validated prognostic unfavorable (3.44e-7)" "validated prognostic unfavorable (1.16e-4)" "validated prognostic unfavorable (1.72e-4)" "unprognostic (1.66e-2)" "unprognostic (6.38e-2)" "unprognostic (2.70e-2)" "unprognostic (2.63e-1)" "unprognostic (6.95e-3)" "unprognostic (1.80e-2)" "unprognostic (1.70e-1)" "unprognostic (4.82e-2)" "unprognostic (4.35e-2)" "potential prognostic unfavorable (1.02e-4)" "unprognostic (1.73e-1)" "unprognostic (4.15e-1)" "unprognostic (1.37e-1)" EXO5 "C1orf176, DEM1, FLJ21144" ENSG00000164002 "Exonuclease 5" Q9H790 1 40508741-40516038 "Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Tuft cells: 11.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028429 Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 49: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 82: Dendritic cells - Antigen presentation" 2 Nucleoplasm "Nuclear speckles, Cytosol" "HPA028429: " "unprognostic (2.12e-2)" "unprognostic (2.61e-1)" "unprognostic (1.15e-1)" "unprognostic (6.46e-2)" "unprognostic (5.07e-2)" "unprognostic (1.57e-1)" "potential prognostic favorable (7.82e-4)" "unprognostic (1.60e-2)" "unprognostic (3.87e-2)" "validated prognostic favorable (3.65e-6)" "validated prognostic favorable (8.64e-4)" "potential prognostic favorable (7.62e-4)" "potential prognostic unfavorable (2.85e-5)" "unprognostic (1.36e-1)" "unprognostic (4.50e-2)" "unprognostic (6.31e-2)" "unprognostic (7.18e-2)" "unprognostic (1.86e-1)" "unprognostic (3.32e-1)" "unprognostic (1.82e-1)" "unprognostic (3.02e-2)" "unprognostic (8.22e-2)" "unprognostic (7.38e-2)" "unprognostic (8.12e-2)" "unprognostic (8.10e-2)" "unprognostic (8.52e-2)" "unprognostic (2.83e-2)" "unprognostic (1.49e-1)" "unprognostic (2.69e-1)" EXOC1 "BM-102, FLJ10893, SEC3, SEC3L1, Sec3p" ENSG00000090989 "Exocyst complex component 1" Q9NV70 4 55853648-55905086 "Essential proteins, Predicted intracellular proteins, Transporters" "Antiviral defense, Exocytosis, Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037706, HPA044873" Uncertain Uncertain "Plasma membrane,Microtubules,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 30: White matter - Myelination" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 7: Non-specific - Transcription" 78 "Plasma membrane, Microtubules" Cytosol "HPA037706: , HPA044873: " "unprognostic (8.15e-2)" "potential prognostic unfavorable (3.37e-4)" "unprognostic (2.63e-1)" "unprognostic (1.65e-1)" "unprognostic (2.88e-1)" "unprognostic (2.45e-2)" "unprognostic (2.80e-1)" "unprognostic (3.13e-3)" "unprognostic (3.71e-1)" "unprognostic (5.53e-3)" "potential prognostic favorable (1.12e-5)" "unprognostic (2.58e-3)" "unprognostic (6.31e-2)" "potential prognostic unfavorable (3.11e-4)" "unprognostic (7.03e-3)" "unprognostic (1.56e-2)" "unprognostic (2.36e-2)" "unprognostic (8.17e-2)" "unprognostic (2.98e-1)" "unprognostic (1.07e-1)" "unprognostic (2.32e-1)" "unprognostic (4.58e-3)" "unprognostic (4.02e-2)" "unprognostic (1.52e-1)" "unprognostic (1.00e-3)" "unprognostic (3.02e-1)" "unprognostic (2.93e-2)" "unprognostic (2.11e-1)" "unprognostic (4.52e-2)" "unprognostic (1.62e-1)" "unprognostic (6.23e-2)" EXOC1L ENSG00000250821 "Exocyst complex component 1 like" A0A1B0GW35 4 55819790-55837489 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Adipocytes: 2.1;Early spermatids: 11.6;Lactotrophs: 1.3;Late spermatids: 8.9;Retinal pigment epithelial cells: 4.3" "Cell type enhanced" "Detected in some" "LAMP5-LHX6 and Chandelier: 9.7;splatter: 2.7;thalamic excitatory: 3.7" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 20 "NK-cell: 1.9" "Lineage enriched" "Detected in single" 20 "NK-cells: 1.9" "Not detected" "Not detected" "Skin - Sebaceous gland cells, Testis - Late spermatids" "Region enriched" "Detected in single" 4 "pons and medulla: 2.8" "Not detected" "Not detected" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 47: Leukemia - Hemostasis" "Cluster 98: Neurons - Neurotransmission & signaling" EXOC2 "FLJ11026, Sec5, SEC5L1" ENSG00000112685 "Exocyst complex component 2" Q96KP1 6 485154-693139 "Disease related genes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins, Transporters" "Exocytosis, Protein transport, Transport" "Disease variant, Intellectual disability, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032093 Approved Vesicles NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 30: White matter - Myelination" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 7: Non-specific - Transcription" 37 Vesicles "HPA032093: " "unprognostic (4.05e-2)" "unprognostic (3.24e-2)" "unprognostic (4.19e-2)" "unprognostic (3.52e-2)" "unprognostic (9.80e-2)" "unprognostic (8.60e-3)" "unprognostic (3.93e-2)" "unprognostic (5.01e-2)" "unprognostic (3.14e-2)" "unprognostic (3.95e-3)" "potential prognostic favorable (1.11e-5)" "unprognostic (3.52e-2)" "unprognostic (4.98e-2)" "unprognostic (5.51e-3)" "unprognostic (6.80e-2)" "unprognostic (4.54e-1)" "unprognostic (1.29e-1)" "unprognostic (7.77e-2)" "unprognostic (8.87e-2)" "unprognostic (1.87e-1)" "unprognostic (2.51e-2)" "unprognostic (6.06e-2)" "unprognostic (1.10e-1)" "unprognostic (1.36e-1)" "unprognostic (5.45e-2)" "unprognostic (1.15e-1)" "unprognostic (8.02e-2)" "unprognostic (3.27e-1)" "unprognostic (3.30e-1)" "unprognostic (2.31e-2)" "unprognostic (3.41e-1)" EXOC3 "Sec6, SEC6L1" ENSG00000180104 "Exocyst complex component 3" O60645 5 443175-471937 "Essential proteins, Predicted intracellular proteins, Transporters" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 61.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070202 Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 7: Non-specific - Transcription" 33 "Plasma membrane, Cytosol" "HPA070202: " "unprognostic (1.08e-1)" "unprognostic (1.06e-2)" "unprognostic (3.19e-2)" "unprognostic (9.69e-2)" "unprognostic (9.23e-2)" "unprognostic (1.22e-1)" "unprognostic (1.57e-1)" "unprognostic (1.20e-2)" "unprognostic (5.83e-2)" "unprognostic (3.63e-2)" "potential prognostic favorable (3.68e-9)" "unprognostic (4.51e-3)" "unprognostic (8.08e-2)" "unprognostic (1.00e-3)" "unprognostic (1.17e-2)" "unprognostic (3.18e-1)" "unprognostic (9.85e-2)" "unprognostic (6.67e-2)" "unprognostic (1.57e-2)" "unprognostic (2.58e-1)" "unprognostic (2.58e-2)" "unprognostic (2.73e-1)" "unprognostic (2.12e-2)" "unprognostic (4.99e-2)" "unprognostic (8.54e-3)" "unprognostic (3.97e-1)" "unprognostic (2.07e-1)" "unprognostic (2.20e-1)" "unprognostic (1.28e-1)" "unprognostic (1.05e-1)" "unprognostic (3.47e-1)" EXOC3L1 "EXOC3L, FLJ35539, FLJ35587" ENSG00000179044 "Exocyst complex component 3 like 1" Q86VI1 16 67184379-67190185 "Predicted intracellular proteins" Exocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 43.9" "Cell type enhanced" "Detected in some" "Early primary spermatocytes: 11.8;Enterocytes: 7.4;Extravillous trophoblasts: 7.5;Granulosa cells: 14.6;Late spermatids: 7.9;Leydig cells: 11.6;Lymphatic endothelial cells: 27.9;Ovarian stromal cells: 20.6;Peritubular myoid cells: 20.2;Vascular endothelial cells: 17.6" "Cell type enhanced" "Detected in some" "endothelial cell: 4.4;lower rhombic lip: 4.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose visceral - Endothelial cells, Liver - Vascular endothelial cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA029574 Uncertain Approved "Vesicles,Plasma membrane" NA NA "Cluster 5: Spleen - Immune response" "Cluster 37: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 7 "Vesicles, Plasma membrane" "HPA029574: " "unprognostic (1.11e-1)" "unprognostic (4.59e-3)" "unprognostic (1.95e-2)" "unprognostic (3.35e-3)" "unprognostic (4.15e-2)" "unprognostic (1.12e-1)" "unprognostic (2.93e-1)" "unprognostic (5.80e-2)" "unprognostic (1.12e-1)" "validated prognostic favorable (2.66e-8)" "validated prognostic favorable (3.04e-4)" "unprognostic (1.04e-2)" "unprognostic (3.69e-2)" "potential prognostic favorable (1.49e-4)" "unprognostic (2.20e-1)" "unprognostic (1.70e-2)" "unprognostic (6.14e-3)" "unprognostic (5.10e-2)" "unprognostic (8.15e-2)" "unprognostic (9.43e-3)" "unprognostic (2.49e-1)" "unprognostic (1.71e-1)" "unprognostic (2.60e-1)" "unprognostic (6.68e-2)" "unprognostic (3.11e-1)" "unprognostic (5.39e-1)" "unprognostic (1.98e-1)" "unprognostic (2.49e-2)" EXOC3L2 "FLJ36147, XTP7" ENSG00000283632 "Exocyst complex component 3 like 2" 19 45212370-45245407 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "kidney: 20.6;thyroid gland: 18.1" "Cell type enhanced" "Detected in some" "Megakaryocyte progenitors: 27.3;Megakaryocytes: 80.4;Oocytes: 46.1;Platelets: 32.5;Undifferentiated spermatogonia: 17.1;Vascular endothelial cells: 59.5" "Cell type enhanced" "Detected in some" "endothelial cell: 9.4" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 26.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Leukemia: 3.0" "Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Liver - Vascular endothelial cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041595, HPA061110" Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Vesicles,Mid piece" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 6: Non-specific - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "Golgi apparatus, Vesicles" "Nucleoplasm, Nucleoli, Mid piece" "HPA041595: , HPA061110: " "unprognostic (7.57e-2)" "unprognostic (2.49e-1)" "unprognostic (2.99e-1)" "unprognostic (3.47e-1)" "unprognostic (2.07e-2)" "unprognostic (2.88e-2)" "unprognostic (2.70e-2)" "unprognostic (8.44e-3)" "unprognostic (2.44e-2)" "validated prognostic favorable (4.97e-9)" "validated prognostic favorable (1.39e-5)" "unprognostic (2.02e-3)" "validated prognostic favorable (1.91e-5)" "validated prognostic favorable (3.03e-5)" "unprognostic (4.28e-1)" "unprognostic (3.24e-1)" "unprognostic (4.52e-2)" "unprognostic (2.70e-2)" "unprognostic (1.96e-1)" "potential prognostic favorable (3.64e-4)" "unprognostic (6.59e-2)" "unprognostic (6.10e-2)" "unprognostic (5.69e-2)" "unprognostic (9.31e-3)" "unprognostic (4.55e-2)" "unprognostic (4.93e-2)" "unprognostic (3.30e-1)" "unprognostic (1.54e-1)" EXOC3L4 C14orf73 ENSG00000205436 "Exocyst complex component 3 like 4" Q17RC7 14 103094725-103110559 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 17.1;liver: 20.9" "Cell type enhanced" "Detected in some" "Cholangiocytes: 26.9;Enterocytes: 91.0;Foveolar cells: 30.0;Gastric chief cells: 21.8;Goblet cells: 17.3;Hepatocytes: 42.1;Megakaryocytes: 61.8;Mucous neck cells: 30.3;Myosatellite cells: 24.1;Proximal tubule cells: 44.9;Tuft cells: 46.1" "Cell type enhanced" "Detected in single" "fibroblast: 2.3" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 6.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 2.3" "Pituitary gland - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043661 Approved NA NA "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 18: Liver cancer - Metabolism" "Cluster 1: Enterocytes - Absorption and Digestion" "HPA043661: " "unprognostic (1.87e-2)" "unprognostic (2.50e-1)" "unprognostic (3.24e-1)" "unprognostic (1.46e-1)" "potential prognostic favorable (9.34e-6)" "unprognostic (7.94e-3)" "unprognostic (4.87e-2)" "unprognostic (6.95e-2)" "potential prognostic favorable (1.72e-5)" "unprognostic (4.30e-2)" "unprognostic (2.07e-1)" "unprognostic (1.46e-1)" "unprognostic (1.37e-3)" "unprognostic (1.77e-1)" "unprognostic (2.15e-2)" EXOC4 "KIAA1699, MGC27170, SEC8, SEC8L1, Sec8p" ENSG00000131558 "Exocyst complex component 4" Q96A65 7 133253073-134066589 "Plasma proteins, Predicted intracellular proteins, Transporters" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Rod photoreceptor cells: 2892.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031443 Approved NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 79: Photoreceptor cells - Phototransduction" 68 "HPA031443: " "unprognostic (6.85e-2)" "unprognostic (9.70e-2)" "unprognostic (4.67e-2)" "unprognostic (3.02e-2)" "unprognostic (5.29e-2)" "unprognostic (1.80e-1)" "unprognostic (7.89e-2)" "unprognostic (2.76e-2)" "unprognostic (9.50e-3)" "potential prognostic unfavorable (5.47e-4)" "potential prognostic favorable (4.67e-8)" "unprognostic (4.68e-2)" "unprognostic (9.63e-3)" "unprognostic (2.46e-2)" "potential prognostic unfavorable (3.05e-4)" "unprognostic (5.35e-2)" "unprognostic (1.11e-2)" "unprognostic (2.65e-1)" "unprognostic (9.42e-2)" "unprognostic (1.87e-2)" "unprognostic (5.84e-2)" "potential prognostic unfavorable (1.51e-4)" "unprognostic (2.12e-2)" "unprognostic (1.28e-1)" "unprognostic (7.83e-2)" "unprognostic (8.93e-2)" "unprognostic (2.70e-1)" "unprognostic (6.56e-2)" "unprognostic (2.33e-1)" "unprognostic (1.85e-1)" "unprognostic (4.68e-1)" EXOC5 "SEC10, SEC10L1, SEC10P" ENSG00000070367 "Exocyst complex component 5" O00471 14 57200507-57268905 "Essential proteins, Predicted intracellular proteins, Transporters" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060837, HPA067574" Approved Approved Vesicles NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 34: Ciliated cells - Cilia assembly & function" 78 Vesicles "HPA060837: , HPA067574: " "unprognostic (2.85e-1)" "unprognostic (1.66e-1)" "unprognostic (1.14e-2)" "unprognostic (9.23e-3)" "unprognostic (3.32e-1)" "unprognostic (6.77e-2)" "unprognostic (2.95e-2)" "unprognostic (5.94e-2)" "unprognostic (6.62e-2)" "unprognostic (1.12e-3)" "potential prognostic favorable (1.12e-5)" "unprognostic (6.48e-3)" "unprognostic (1.14e-1)" "unprognostic (1.43e-2)" "unprognostic (7.89e-2)" "unprognostic (6.22e-2)" "unprognostic (1.28e-1)" "unprognostic (9.74e-2)" "unprognostic (1.44e-1)" "unprognostic (6.38e-3)" "potential prognostic unfavorable (5.50e-5)" "unprognostic (1.44e-1)" "unprognostic (8.86e-3)" "unprognostic (1.04e-1)" "unprognostic (2.17e-1)" "unprognostic (1.07e-2)" "unprognostic (1.99e-1)" "unprognostic (5.83e-2)" "unprognostic (1.25e-1)" "unprognostic (1.71e-1)" "unprognostic (1.46e-1)" EXOC6 "DKFZp761I2124, EXOC6A, FLJ1125, MGC33397, Sec15, SEC15L, SEC15L1" ENSG00000138190 "Exocyst complex component 6" Q8TAG9 10 92826831-93059493 "Plasma proteins, Predicted intracellular proteins, Transporters" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "retina: 152.0" "Cell type enhanced" "Detected in all" "Myonuclei: 1054.9;Neutrophil progenitors: 592.8;Neutrophils: 876.3;Rod photoreceptor cells: 469.7;Sertoli cells: 630.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 30.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adrenal gland - Adrenal cortex cells, Skeletal muscle - Skeletal myocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036285 Approved Uncertain "Centrosome,Basal body,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 42: Retina - Visual perception" "Cluster 23: Choroid plexus - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 37 "Centrosome, Basal body, Cytosol" "HPA036285: " "unprognostic (1.47e-2)" "unprognostic (3.94e-2)" "unprognostic (3.90e-2)" "unprognostic (1.92e-1)" "unprognostic (1.05e-2)" "unprognostic (1.21e-1)" "unprognostic (9.67e-2)" "potential prognostic favorable (2.09e-4)" "unprognostic (6.84e-2)" "unprognostic (2.50e-2)" "potential prognostic favorable (8.64e-6)" "unprognostic (3.48e-2)" "unprognostic (3.14e-1)" "unprognostic (6.86e-2)" "unprognostic (3.66e-3)" "unprognostic (1.20e-1)" "unprognostic (7.22e-2)" "unprognostic (2.49e-1)" "unprognostic (2.81e-1)" "unprognostic (5.04e-2)" "unprognostic (1.53e-3)" "unprognostic (2.90e-2)" "unprognostic (2.50e-1)" "unprognostic (3.57e-2)" "unprognostic (1.43e-1)" "unprognostic (1.25e-1)" "unprognostic (3.42e-1)" "unprognostic (5.27e-2)" "unprognostic (8.93e-2)" "unprognostic (3.27e-1)" "unprognostic (2.14e-1)" EXOC6B "KIAA0919, SEC15B, SEC15L2" ENSG00000144036 "Exocyst complex component 6B" Q9Y2D4 2 72175984-72826041 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Exocytosis, Protein transport, Transport" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 47.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 1237.6;Oligodendrocytes: 1149.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Lung - Fibroblasts_1, Skin - Keratinocyte (other), Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034546, HPA063991" Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 35: Non-specific - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 26: Keratinocytes - Keratinization" 27 "Nucleoplasm, Nuclear bodies" Cytosol "HPA034546: , HPA063991: " "unprognostic (1.49e-1)" "unprognostic (7.78e-2)" "unprognostic (1.73e-1)" "unprognostic (2.90e-2)" "unprognostic (1.09e-1)" "unprognostic (2.52e-2)" "unprognostic (1.38e-1)" "unprognostic (3.68e-2)" "unprognostic (2.15e-1)" "unprognostic (3.14e-2)" "potential prognostic favorable (2.61e-6)" "unprognostic (1.89e-3)" "unprognostic (1.88e-1)" "unprognostic (2.82e-2)" "unprognostic (3.63e-1)" "unprognostic (3.91e-2)" "unprognostic (4.56e-2)" "unprognostic (4.44e-1)" "unprognostic (2.93e-2)" "potential prognostic unfavorable (6.87e-4)" "unprognostic (1.11e-3)" "unprognostic (1.28e-2)" "unprognostic (3.86e-2)" "unprognostic (1.74e-1)" "unprognostic (1.45e-1)" "unprognostic (2.98e-1)" "unprognostic (9.03e-2)" "unprognostic (1.30e-2)" "unprognostic (1.98e-1)" "unprognostic (8.09e-2)" "unprognostic (3.66e-2)" EXOC7 "BLOM4, EXO70, Exo70p, KIAA1067, YJL085W" ENSG00000182473 "Exocyst complex component 7" Q9UPT5 17 76081016-76121576 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Exocytosis, Protein transport, Transport" Epilepsy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 180.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022840, HPA022842" Supported Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 24: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 44 Cytosol "Vesicles, Plasma membrane" "HPA022840: , HPA022842: " "unprognostic (6.59e-2)" "unprognostic (4.07e-1)" "unprognostic (2.30e-3)" "unprognostic (7.49e-2)" "unprognostic (5.38e-2)" "unprognostic (2.60e-2)" "unprognostic (1.52e-1)" "unprognostic (8.80e-3)" "unprognostic (1.31e-1)" "unprognostic (1.65e-3)" "potential prognostic favorable (2.32e-7)" "unprognostic (5.63e-3)" "unprognostic (1.17e-1)" "unprognostic (4.79e-2)" "unprognostic (2.67e-2)" "unprognostic (1.63e-1)" "unprognostic (4.28e-3)" "unprognostic (1.91e-1)" "unprognostic (6.60e-2)" "unprognostic (2.16e-1)" "unprognostic (9.06e-2)" "unprognostic (9.75e-2)" "unprognostic (1.59e-1)" "unprognostic (9.55e-2)" "unprognostic (7.42e-2)" "unprognostic (3.42e-3)" "unprognostic (6.04e-2)" "unprognostic (2.13e-1)" "unprognostic (1.30e-1)" "unprognostic (7.64e-2)" "unprognostic (1.26e-1)" EXOC8 "EXO84, Exo84p, SEC84" ENSG00000116903 "Exocyst complex component 8" Q8IYI6 1 231332753-231337852 "Disease related genes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Exocytosis, Protein transport, Transport" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 31.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027438 Approved Approved Cytosol NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 103 Cytosol "HPA027438: " "unprognostic (1.35e-1)" "unprognostic (1.95e-2)" "unprognostic (1.26e-1)" "unprognostic (1.74e-3)" "unprognostic (1.44e-1)" "unprognostic (1.02e-1)" "unprognostic (5.33e-2)" "unprognostic (2.68e-2)" "unprognostic (4.66e-2)" "unprognostic (1.01e-1)" "potential prognostic favorable (5.72e-6)" "unprognostic (3.30e-2)" "unprognostic (1.67e-1)" "unprognostic (1.31e-1)" "unprognostic (4.80e-1)" "unprognostic (4.98e-2)" "unprognostic (8.20e-2)" "unprognostic (4.20e-2)" "unprognostic (1.38e-1)" "unprognostic (6.09e-2)" "unprognostic (4.21e-2)" "unprognostic (1.19e-1)" "unprognostic (1.10e-1)" "unprognostic (1.58e-1)" "unprognostic (3.81e-2)" "unprognostic (1.47e-2)" "unprognostic (4.41e-2)" "unprognostic (2.35e-1)" "unprognostic (3.84e-1)" "unprognostic (8.21e-2)" "unprognostic (1.16e-1)" EXOG "ENDOGL1, ENDOGL2, ENGL, ENGL-a, ENGL-b" ENSG00000157036 "Exo/endonuclease G" Q9Y2C4 3 38496127-38542161 "Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 161.8;Myonuclei: 112.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012531, HPA071050" Enhanced Supported Mitochondria NA NA "Cluster 24: Non-specific - Transcription" "Cluster 35: Non-specific - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 55: Myocytes - Oxidative muscle function" 1 Mitochondria "HPA012531: , HPA071050: " "potential prognostic favorable (6.44e-4)" "unprognostic (1.82e-1)" "unprognostic (1.70e-1)" "unprognostic (4.60e-2)" "unprognostic (2.78e-2)" "unprognostic (1.15e-1)" "unprognostic (1.93e-2)" "unprognostic (9.20e-2)" "unprognostic (1.11e-3)" "unprognostic (2.10e-3)" "unprognostic (1.00e-1)" "unprognostic (5.91e-2)" "unprognostic (1.16e-3)" "unprognostic (2.13e-3)" "unprognostic (6.75e-2)" "unprognostic (1.44e-1)" "unprognostic (3.75e-2)" "unprognostic (4.29e-1)" "unprognostic (1.54e-1)" "unprognostic (2.14e-1)" "unprognostic (1.34e-1)" "potential prognostic favorable (1.70e-5)" "unprognostic (1.05e-3)" "potential prognostic unfavorable (8.05e-4)" "unprognostic (2.26e-1)" "unprognostic (7.08e-2)" "unprognostic (1.03e-1)" "unprognostic (1.57e-1)" "unprognostic (2.32e-1)" "unprognostic (2.51e-1)" "unprognostic (6.03e-2)" EXOSC1 "CGI-108, CSL4, Csl4p, hCsl4p, p13, SKI4, Ski4p" ENSG00000171311 "Exosome component 1" Q9Y3B2 10 97435909-97446017 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "rRNA processing" RNA-binding "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038370 Approved Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 70: Non-specific - Protein processing" "Cluster 25: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 97: Non-specific - Cellular respiration" 68 "Nuclear bodies" Nucleoplasm "HPA038370: " "unprognostic (2.62e-1)" "unprognostic (2.03e-1)" "unprognostic (2.99e-1)" "unprognostic (2.48e-1)" "unprognostic (1.33e-1)" "unprognostic (3.52e-1)" "unprognostic (4.14e-2)" "potential prognostic favorable (1.27e-5)" "unprognostic (3.27e-3)" "unprognostic (1.19e-1)" "potential prognostic unfavorable (1.49e-6)" "unprognostic (1.06e-3)" "unprognostic (1.62e-1)" "potential prognostic unfavorable (5.62e-4)" "unprognostic (1.15e-1)" "unprognostic (2.25e-2)" "unprognostic (4.06e-2)" "unprognostic (1.46e-2)" "unprognostic (6.23e-2)" "unprognostic (6.61e-2)" "unprognostic (4.28e-3)" "unprognostic (6.14e-2)" "unprognostic (6.96e-2)" "unprognostic (3.19e-1)" "unprognostic (1.20e-2)" "unprognostic (2.44e-1)" "unprognostic (3.43e-2)" "unprognostic (2.31e-1)" "unprognostic (9.34e-2)" "unprognostic (2.52e-2)" "unprognostic (6.83e-3)" EXOSC10 "p2, p3, p4, PM-Scl, PM/Scl-100, PMSCL2, RRP6, Rrp6p" ENSG00000171824 "Exosome component 10" Q01780 1 11066618-11099869 "Essential proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Nonsense-mediated mRNA decay, rRNA processing" "Exonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028470, HPA028484, CAB037141" Supported Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 49: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 37: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 67 "Nucleoli, Nucleoli rim" "Nucleoplasm, Cytosol" "CAB037141: , HPA028470: , HPA028484: " "unprognostic (2.89e-1)" "unprognostic (1.17e-1)" "unprognostic (6.31e-2)" "unprognostic (8.53e-3)" "unprognostic (3.98e-3)" "unprognostic (1.20e-1)" "unprognostic (1.48e-1)" "unprognostic (2.59e-2)" "unprognostic (3.08e-1)" "potential prognostic unfavorable (8.51e-4)" "potential prognostic favorable (2.25e-5)" "unprognostic (2.15e-3)" "unprognostic (1.01e-1)" "validated prognostic unfavorable (4.83e-7)" "validated prognostic unfavorable (8.53e-4)" "unprognostic (5.79e-2)" "unprognostic (3.94e-2)" "unprognostic (3.14e-1)" "unprognostic (1.79e-1)" "unprognostic (1.41e-1)" "unprognostic (1.36e-1)" "unprognostic (2.04e-2)" "unprognostic (2.34e-2)" "unprognostic (8.27e-2)" "unprognostic (2.78e-2)" "unprognostic (2.93e-3)" "unprognostic (1.34e-1)" "unprognostic (2.68e-1)" "unprognostic (1.32e-1)" "unprognostic (5.75e-2)" "unprognostic (4.41e-2)" EXOSC2 "hRrp4p, p7, RRP4, Rrp4p" ENSG00000130713 "Exosome component 2" Q13868 9 130693721-130707288 "Disease related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "rRNA processing" RNA-binding "Deafness, Disease variant, Dwarfism, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 42.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pancreas - Endothelial cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021756, HPA021790" Approved Supported Nucleoplasm,Nucleoli NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 17: Non-specific - RNA processing" 71 "Nucleoplasm, Nucleoli" "HPA021756: , HPA021790: " "unprognostic (5.51e-3)" "unprognostic (1.43e-2)" "unprognostic (1.30e-1)" "unprognostic (2.29e-1)" "unprognostic (2.04e-1)" "unprognostic (1.44e-2)" "unprognostic (9.52e-2)" "unprognostic (2.13e-3)" "unprognostic (1.74e-3)" "unprognostic (6.96e-3)" "potential prognostic favorable (4.74e-7)" "unprognostic (1.63e-3)" "unprognostic (9.46e-2)" "potential prognostic unfavorable (1.01e-5)" "unprognostic (2.35e-3)" "potential prognostic unfavorable (3.50e-5)" "unprognostic (1.46e-3)" "unprognostic (2.37e-1)" "unprognostic (4.68e-3)" "unprognostic (3.44e-2)" "unprognostic (1.02e-1)" "unprognostic (1.99e-2)" "unprognostic (2.99e-2)" "unprognostic (1.28e-2)" "unprognostic (5.42e-2)" "unprognostic (1.05e-1)" "unprognostic (5.46e-2)" "unprognostic (5.93e-2)" "unprognostic (2.79e-1)" "unprognostic (7.75e-2)" "unprognostic (2.07e-1)" EXOSC3 "CGI-102, hRrp-40, hRrp40p, p10, RRP40, Rrp40p" ENSG00000107371 "Exosome component 3" Q9NQT5 9 37759234-37832117 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "rRNA processing" RNA-binding "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 32.5;Bergmann glia: 37.6;Brain excitatory neurons: 32.5;Brain inhibitory neurons: 30.5;Choroid plexus epithelial cells: 27.9;Early spermatids: 40.4;Ependymal cells: 24.4;Late primary spermatocytes: 27.7;Microglia: 25.6;Oligodendrocyte progenitor cells: 31.7;Oligodendrocytes: 37.9;Other brain neurons: 23.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020485 Supported Supported Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 39: Testis - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 22: Non-specific - Basic cellular functions" 65 Nucleoplasm "HPA020485: " "unprognostic (1.34e-2)" "unprognostic (1.15e-1)" "unprognostic (3.02e-1)" "unprognostic (3.66e-1)" "unprognostic (2.37e-1)" "unprognostic (1.48e-1)" "unprognostic (1.83e-2)" "unprognostic (1.58e-2)" "unprognostic (2.61e-2)" "unprognostic (2.91e-1)" "potential prognostic favorable (1.17e-5)" "unprognostic (1.51e-1)" "unprognostic (7.97e-2)" "potential prognostic unfavorable (1.27e-4)" "unprognostic (1.76e-2)" "unprognostic (3.24e-3)" "unprognostic (2.19e-2)" "unprognostic (7.45e-2)" "unprognostic (9.13e-3)" "unprognostic (5.59e-2)" "unprognostic (2.68e-1)" "unprognostic (4.11e-2)" "unprognostic (2.65e-2)" "unprognostic (1.08e-2)" "unprognostic (3.27e-2)" "unprognostic (2.61e-1)" "unprognostic (2.20e-3)" "unprognostic (3.85e-2)" "unprognostic (1.89e-1)" "unprognostic (6.36e-2)" "unprognostic (1.29e-1)" EXOSC4 "FLJ20591, hRrp41p, p12A, RRP41, RRP41A, Rrp41p, SKI6, Ski6p" ENSG00000178896 "Exosome component 4" Q9NPD3 8 144078648-144080648 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "rRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 94.0" "Cell type enhanced" "Detected in some" "Astrocytes: 4.0;Bergmann glia: 3.8;Brain excitatory neurons: 5.7;Brain inhibitory neurons: 5.4;Ependymal cells: 3.0;Loop of henle epithelial cells: 2.8;Microglia: 3.2;Oligodendrocyte progenitor cells: 4.4;Oligodendrocytes: 6.0;Other brain neurons: 7.9;Papillary tip epithelial cells: 2.6;Renal collecting duct intercalated cells: 1.8;Renal collecting duct principal cells: 2.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024792, HPA065103" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 12: Non-specific - Vasculature" "Cluster 40: Non-specific - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" 81 "Nucleoplasm, Cytosol" Vesicles "HPA024792: , HPA065103: " "unprognostic (3.56e-2)" "unprognostic (1.36e-1)" "unprognostic (7.66e-2)" "unprognostic (3.38e-2)" "unprognostic (1.62e-1)" "unprognostic (1.15e-1)" "unprognostic (6.09e-2)" "potential prognostic favorable (1.22e-4)" "unprognostic (2.84e-2)" "unprognostic (1.23e-2)" "unprognostic (1.21e-1)" "unprognostic (1.70e-2)" "unprognostic (7.67e-2)" "unprognostic (6.46e-3)" "unprognostic (8.02e-3)" "unprognostic (1.36e-3)" "unprognostic (2.58e-2)" "unprognostic (2.15e-2)" "unprognostic (9.54e-2)" "potential prognostic favorable (8.93e-4)" "unprognostic (1.33e-1)" "unprognostic (7.06e-2)" "unprognostic (1.41e-1)" "unprognostic (2.10e-1)" "unprognostic (1.34e-1)" "unprognostic (2.15e-2)" "unprognostic (6.61e-2)" "unprognostic (2.23e-1)" "unprognostic (1.45e-1)" "unprognostic (2.21e-1)" "unprognostic (2.01e-1)" EXOSC5 "hRrp46p, MGC12901, p12B, RRP41B, RRP46, Rrp46p" ENSG00000077348 "Exosome component 5" Q9NQT4 19 41386371-41397362 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "rRNA processing" DNA-binding "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 64.6;Esophageal basal cells: 84.6;Extravillous trophoblasts: 148.6;Migrating cytotrophoblasts: 94.0;Oocytes: 73.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053150, HPA055677" Approved Enhanced Nucleoplasm,Nucleoli NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 24: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 107 Nucleoli Nucleoplasm "HPA053150: , HPA055677: " "unprognostic (8.20e-2)" "unprognostic (2.60e-1)" "unprognostic (3.03e-2)" "unprognostic (1.70e-1)" "unprognostic (3.73e-2)" "unprognostic (8.22e-2)" "unprognostic (6.51e-2)" "unprognostic (2.07e-1)" "unprognostic (7.91e-2)" "unprognostic (6.66e-2)" "unprognostic (1.74e-2)" "unprognostic (8.39e-3)" "potential prognostic unfavorable (3.06e-5)" "unprognostic (1.56e-3)" "potential prognostic unfavorable (4.63e-5)" "unprognostic (2.09e-2)" "unprognostic (4.85e-2)" "unprognostic (1.70e-2)" "unprognostic (4.00e-1)" "unprognostic (1.04e-1)" "unprognostic (7.90e-2)" "unprognostic (1.26e-1)" "unprognostic (6.07e-2)" "unprognostic (5.08e-3)" "potential prognostic favorable (6.82e-4)" "unprognostic (9.17e-3)" "unprognostic (1.96e-1)" "unprognostic (1.08e-1)" "unprognostic (2.98e-1)" "unprognostic (1.54e-1)" "unprognostic (3.92e-1)" EXOSC6 "EAP4, hMtr3p, MTR3, Mtr3p, p11" ENSG00000223496 "Exosome component 6" Q5RKV6 16 70246778-70251940 "Essential proteins, Predicted intracellular proteins" "rRNA processing" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 2: Non-specific - Mixed function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 17: Non-specific - RNA processing" 36 "unprognostic (1.72e-1)" "unprognostic (8.97e-2)" "unprognostic (7.87e-2)" "unprognostic (2.76e-1)" "unprognostic (4.58e-3)" "unprognostic (2.89e-1)" "unprognostic (4.64e-2)" "unprognostic (1.01e-3)" "unprognostic (2.84e-2)" "unprognostic (1.22e-2)" "unprognostic (5.91e-2)" "unprognostic (6.99e-2)" "unprognostic (3.78e-2)" "unprognostic (3.19e-3)" "potential prognostic unfavorable (4.42e-4)" "unprognostic (2.73e-3)" "unprognostic (1.56e-1)" "unprognostic (6.40e-3)" "potential prognostic favorable (2.92e-4)" "unprognostic (1.42e-1)" "unprognostic (1.57e-1)" "unprognostic (9.08e-3)" "unprognostic (6.57e-2)" "unprognostic (3.87e-1)" "unprognostic (1.84e-1)" "unprognostic (2.65e-2)" "unprognostic (1.19e-1)" "unprognostic (9.56e-2)" "unprognostic (2.76e-1)" "unprognostic (5.88e-1)" "unprognostic (5.11e-2)" EXOSC7 "EAP1, hRrp42p, KIAA0116, p8, RRP42, Rrp42p" ENSG00000075914 "Exosome component 7" Q15024 3 44975241-45036066 "Essential proteins, Predicted intracellular proteins" "rRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 167.2;Oocytes: 128.9;Renal collecting duct intercalated cells: 180.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036182, HPA057980" Approved Supported "Nuclear speckles" NA NA 33000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 55: Myocytes - Oxidative muscle function" 61 "Nuclear speckles" "HPA036182: , HPA057980: " "unprognostic (7.85e-2)" "unprognostic (1.22e-2)" "unprognostic (3.43e-1)" "unprognostic (2.06e-2)" "unprognostic (3.31e-1)" "unprognostic (3.63e-2)" "unprognostic (1.40e-1)" "potential prognostic favorable (1.96e-4)" "unprognostic (7.25e-2)" "unprognostic (2.56e-2)" "unprognostic (2.36e-2)" "unprognostic (7.86e-2)" "unprognostic (1.22e-1)" "unprognostic (8.71e-3)" "potential prognostic unfavorable (7.49e-4)" "unprognostic (3.90e-1)" "potential prognostic unfavorable (7.06e-4)" "unprognostic (3.42e-2)" "unprognostic (3.06e-1)" "unprognostic (1.13e-1)" "unprognostic (2.01e-2)" "unprognostic (2.28e-3)" "unprognostic (1.98e-1)" "unprognostic (2.70e-2)" "unprognostic (2.96e-2)" "unprognostic (3.29e-2)" "unprognostic (3.84e-1)" "unprognostic (1.65e-1)" "unprognostic (1.87e-1)" "unprognostic (2.49e-1)" "unprognostic (3.21e-2)" EXOSC8 "bA421P11.3, CIP3, EAP2, OIP2, p9, RRP43, Rrp43p" ENSG00000120699 "Exosome component 8" Q96B26 13 36998816-37025881 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "rRNA processing" RNA-binding "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 265.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034240, HPA039702, HPA043942, HPA075230" Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center,Mitotic chromosome,Vesicles,Cytosol" Yes NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 39: Testis - Nuclear processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 96 "Nucleoli fibrillar center, Mitotic chromosome" "Nucleoplasm, Vesicles, Cytosol" "CAB034240: , HPA039702: , HPA043942: , HPA075230: " "potential prognostic unfavorable (3.42e-4)" "unprognostic (1.91e-1)" "unprognostic (2.18e-1)" "unprognostic (1.12e-2)" "unprognostic (8.56e-2)" "unprognostic (1.97e-2)" "unprognostic (4.49e-2)" "unprognostic (2.35e-2)" "unprognostic (5.15e-3)" "unprognostic (7.98e-3)" "unprognostic (1.40e-1)" "unprognostic (2.22e-1)" "unprognostic (8.86e-3)" "unprognostic (1.55e-2)" "unprognostic (1.05e-2)" "unprognostic (4.88e-3)" "unprognostic (1.05e-2)" "unprognostic (1.41e-1)" "unprognostic (2.04e-1)" "unprognostic (1.05e-1)" "unprognostic (6.40e-2)" "unprognostic (4.65e-2)" "potential prognostic unfavorable (7.16e-5)" "unprognostic (1.76e-1)" "unprognostic (1.32e-1)" "unprognostic (2.47e-1)" "unprognostic (6.37e-3)" "unprognostic (6.52e-3)" "unprognostic (2.24e-1)" "unprognostic (1.88e-1)" "unprognostic (7.09e-3)" EXOSC9 "p5, p6, PM/Scl-75, PMSCL1, RRP45, Rrp45p" ENSG00000123737 "Exosome component 9" Q06265 4 121801318-121817021 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "rRNA processing" RNA-binding "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 106.0;Early spermatids: 131.2;Late primary spermatocytes: 313.4;Oocytes: 101.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041838, HPA048257, CAB070171" Approved Enhanced Nucleoplasm,Nucleoli NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 39: Testis - Nuclear processes" "Cluster 34: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 38 Nucleoli Nucleoplasm "CAB070171: , HPA041838: , HPA048257: " "unprognostic (5.53e-2)" "unprognostic (1.63e-2)" "unprognostic (1.84e-2)" "unprognostic (2.16e-1)" "unprognostic (7.26e-2)" "unprognostic (2.04e-1)" "unprognostic (6.23e-2)" "unprognostic (1.99e-1)" "potential prognostic unfavorable (9.41e-4)" "unprognostic (1.80e-3)" "potential prognostic favorable (5.49e-4)" "unprognostic (5.97e-3)" "unprognostic (3.21e-2)" "potential prognostic unfavorable (4.81e-4)" "unprognostic (5.59e-3)" "unprognostic (3.86e-3)" "unprognostic (6.86e-3)" "unprognostic (2.70e-2)" "unprognostic (8.94e-2)" "unprognostic (3.86e-2)" "unprognostic (2.39e-1)" "unprognostic (8.74e-2)" "unprognostic (3.01e-3)" "unprognostic (1.55e-3)" "unprognostic (1.85e-1)" "unprognostic (2.02e-2)" "unprognostic (2.23e-1)" "unprognostic (2.20e-1)" "unprognostic (2.77e-1)" "unprognostic (3.81e-1)" "unprognostic (5.31e-2)" EXPH5 SLAC2-B ENSG00000110723 "Exophilin 5" Q8NEV8 11 108505435-108593768 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Epidermolysis bullosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 15.1;skin 1: 24.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 272.9;Endometrial ciliated cells: 345.9;Endometrial glandular cells: 405.3;Ependymal cells: 251.4;Podocytes: 908.0" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 275.4;choroid plexus epithelial cell: 159.6;ependymal cell: 220.0;upper rhombic lip: 208.1" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 5 "cerebellum: 144.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Late spermatids" "Group enriched" "Detected in many" 4 "cerebellum: 20.9;cerebral cortex: 6.7" "Region enriched" "Detected in all" 8 "cerebellum: 41.9" "CAB080597, CAB080733" Approved Cytosol NA NA "Cluster 2: Non-specific - Mixed function" "Cluster 35: Non-specific - DNA binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 51: Secretory epithelial cells - Mixed function" 4 Cytosol "CAB080597: , CAB080733: " "unprognostic (3.34e-2)" "unprognostic (2.16e-2)" "unprognostic (2.02e-1)" "unprognostic (8.37e-2)" "unprognostic (1.03e-1)" "unprognostic (2.26e-2)" "unprognostic (3.58e-1)" "unprognostic (3.64e-3)" "unprognostic (1.76e-1)" "potential prognostic favorable (2.27e-5)" "unprognostic (2.79e-3)" "unprognostic (2.73e-1)" "potential prognostic favorable (7.21e-5)" "potential prognostic favorable (7.28e-4)" "unprognostic (4.28e-2)" "unprognostic (1.69e-1)" "unprognostic (2.53e-1)" "unprognostic (1.65e-1)" "unprognostic (2.74e-1)" "unprognostic (5.96e-3)" "unprognostic (1.10e-1)" "unprognostic (2.29e-1)" "unprognostic (4.18e-3)" "unprognostic (2.11e-1)" "unprognostic (3.88e-2)" "unprognostic (5.39e-1)" "unprognostic (3.32e-3)" EXT1 "LGCR, LGS, ttv" ENSG00000182197 "Exostosin glycosyltransferase 1" Q16394 8 117794490-118111826 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes, Disease variant, Hereditary multiple exostoses, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 1643.6;Epididymal basal cells: 1627.1;Kupffer cells: 2691.4;Neutrophils: 2109.8;Ocular epithelial cells: 1595.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044394 Uncertain NA Yes 12000000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 29: Forebrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 100: Stratified epithelial cells - Barrier functions" 6 "HPA044394: " "unprognostic (1.06e-1)" "unprognostic (1.39e-2)" "unprognostic (1.41e-1)" "unprognostic (1.65e-2)" "unprognostic (2.10e-1)" "unprognostic (3.09e-2)" "unprognostic (1.15e-1)" "unprognostic (1.84e-2)" "unprognostic (1.32e-1)" "unprognostic (5.07e-3)" "unprognostic (4.92e-3)" "unprognostic (1.23e-1)" "unprognostic (6.18e-2)" "unprognostic (1.64e-1)" "unprognostic (3.10e-2)" "potential prognostic unfavorable (2.52e-5)" "unprognostic (1.01e-3)" "unprognostic (4.57e-2)" "unprognostic (1.33e-1)" "unprognostic (3.73e-1)" "unprognostic (5.09e-2)" "unprognostic (4.83e-3)" "unprognostic (7.96e-2)" "unprognostic (5.53e-2)" "unprognostic (4.12e-2)" "unprognostic (2.83e-1)" "unprognostic (3.12e-2)" "unprognostic (3.20e-2)" "unprognostic (1.65e-1)" "unprognostic (1.30e-3)" "unprognostic (9.15e-2)" EXT2 SOTV ENSG00000151348 "Exostosin glycosyltransferase 2" Q93063 11 44095648-44251962 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes, Disease variant, Epilepsy, Hereditary multiple exostoses, Intellectual disability, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078409 Supported "Golgi apparatus" "Intracellular and membrane" Enzyme NA NA 21000000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 51: Secretory epithelial cells - Mixed function" 30 "Golgi apparatus" "HPA078409: " "unprognostic (7.82e-2)" "unprognostic (2.22e-2)" "unprognostic (1.21e-1)" "unprognostic (1.80e-2)" "unprognostic (1.39e-2)" "unprognostic (4.39e-2)" "unprognostic (2.67e-2)" "unprognostic (1.30e-1)" "unprognostic (3.54e-3)" "unprognostic (1.56e-2)" "unprognostic (7.24e-3)" "unprognostic (2.66e-1)" "unprognostic (3.20e-2)" "potential prognostic unfavorable (5.81e-4)" "unprognostic (3.95e-3)" "unprognostic (3.32e-2)" "unprognostic (8.47e-3)" "unprognostic (3.26e-1)" "unprognostic (1.98e-1)" "unprognostic (3.88e-2)" "unprognostic (3.15e-3)" "potential prognostic unfavorable (5.25e-4)" "unprognostic (1.85e-1)" "unprognostic (1.70e-1)" "unprognostic (4.89e-3)" "unprognostic (1.88e-1)" "unprognostic (1.63e-1)" "unprognostic (1.21e-2)" "unprognostic (1.85e-1)" "unprognostic (9.65e-2)" "unprognostic (1.77e-1)" EXTL1 "EXTL, MGC70794" ENSG00000158008 "Exostosin like glycosyltransferase 1" Q92935 1 26019884-26036464 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 30.8;skeletal muscle: 11.9;tongue: 27.8" "Group enriched" "Detected in some" 4 "Breast lactating cells: 95.3;Cardiomyocytes: 80.9" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in some" 14 "Skin Cutaneous Melanoma (TCGA): 37.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Rhabdoid: 8.6;skin cancer: 25.6" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010726, HPA037749" Uncertain Approved "Centrosome,Basal body" NA NA 57000 "Cluster 25: Non-specific - Basic cellular processes" "Cluster 51: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 4 "Centrosome, Basal body" "HPA010726: , HPA037749: " "unprognostic (6.62e-2)" "unprognostic (3.80e-3)" "unprognostic (3.64e-2)" "unprognostic (1.01e-3)" "unprognostic (1.18e-1)" EXTL2 ENSG00000162694 "Exostosin like glycosyltransferase 2" Q9UBQ6 1 100872372-100895179 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 122.7;Cytotrophoblasts: 304.4;Migrating cytotrophoblasts: 158.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 84.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020716, HPA068921" Approved Approved Nucleoplasm,Cytosol "Intracellular and membrane" Enzyme NA NA 21000000 "Cluster 41: Basophils - Unknown function" "Cluster 65: Brain - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 37: Non-specific - mRNA processing" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 10 Nucleoplasm Cytosol "CAB020716: , HPA068921: " "unprognostic (2.74e-1)" "unprognostic (1.08e-1)" "unprognostic (3.26e-2)" "unprognostic (6.60e-2)" "unprognostic (2.39e-1)" "unprognostic (3.79e-2)" "unprognostic (5.54e-2)" "unprognostic (1.58e-1)" "unprognostic (1.76e-1)" "unprognostic (1.80e-1)" "potential prognostic favorable (2.62e-8)" "unprognostic (3.13e-2)" "unprognostic (2.44e-1)" "potential prognostic unfavorable (3.82e-5)" "unprognostic (2.52e-1)" "unprognostic (1.25e-2)" "unprognostic (1.89e-1)" "unprognostic (1.28e-1)" "unprognostic (4.80e-2)" "unprognostic (2.29e-1)" "unprognostic (4.07e-1)" "unprognostic (8.54e-2)" "unprognostic (2.07e-1)" "unprognostic (2.09e-1)" "unprognostic (7.86e-2)" "unprognostic (3.47e-2)" "unprognostic (4.15e-2)" "unprognostic (1.60e-1)" "unprognostic (1.38e-1)" "unprognostic (3.77e-2)" "unprognostic (2.28e-1)" EXTL3 "botv, REGR" ENSG00000012232 "Exostosin like glycosyltransferase 3" O43909 8 28600469-28756561 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Receptor, Transferase" "Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Mesothelial cells: 103.3;Neutrophils: 225.4;Rod photoreceptor cells: 122.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 6.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Smooth muscle cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025387 Approved NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 24: Neutrophils - Innate immunity signal integration" 40 "CAB025387: " "unprognostic (5.58e-2)" "unprognostic (2.94e-2)" "unprognostic (4.82e-1)" "unprognostic (5.27e-2)" "unprognostic (4.30e-3)" "unprognostic (2.21e-1)" "unprognostic (1.36e-1)" "unprognostic (1.35e-1)" "unprognostic (1.20e-1)" "unprognostic (4.80e-3)" "potential prognostic favorable (1.19e-6)" "unprognostic (1.33e-3)" "unprognostic (5.16e-3)" "potential prognostic unfavorable (4.24e-5)" "unprognostic (3.08e-2)" "unprognostic (9.19e-3)" "unprognostic (1.92e-2)" "unprognostic (7.04e-2)" "unprognostic (1.56e-1)" "unprognostic (3.40e-1)" "unprognostic (2.46e-3)" "unprognostic (8.52e-2)" "unprognostic (2.52e-2)" "unprognostic (1.47e-2)" "unprognostic (3.79e-2)" "unprognostic (1.77e-2)" "unprognostic (3.87e-1)" "unprognostic (1.06e-1)" "unprognostic (2.69e-1)" "unprognostic (4.58e-2)" "unprognostic (3.91e-2)" EYA1 BOR ENSG00000104313 "EYA transcriptional coactivator and phosphatase 1" Q99502 8 71197433-71592025 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, Hydrolase, Protein phosphatase" "Deafness, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 14.3;parathyroid gland: 22.3;prostate: 11.3" "Cell type enhanced" "Detected in many" "Astrocytes: 330.2;Choroid plexus epithelial cells: 651.8;Corticotrophs: 652.3;Ependymal cells: 559.7;Gonadotrophs: 1089.0;Medullary thymic epithelial cells: 1041.7;Pituitary stem cells: 2528.5;Respiratory basal cells: 443.7;Respiratory ciliated cells: 443.2;Respiratory secretory cells: 384.5;Somatotrophs: 337.1" "Group enriched" "Detected in many" 5 "astrocyte: 360.1;choroid plexus epithelial cell: 539.4;ependymal cell: 580.1;fibroblast: 360.1;medium spiny neuron: 208.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 20.9" "Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Pituitary gland - Gonadotropes, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 26.6" HPA028917 Supported "Nucleoplasm,Nuclear bodies,Vesicles,Primary cilium" NA NA "Cluster 69: Parathyroid gland - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 11: Neuronal - Sensory perception" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 9 "Nucleoplasm, Nuclear bodies" "Vesicles, Primary cilium" "HPA028917: " "unprognostic (1.54e-2)" "unprognostic (2.08e-1)" "unprognostic (3.48e-2)" "potential prognostic favorable (9.69e-5)" "unprognostic (3.98e-1)" "unprognostic (1.95e-2)" "unprognostic (2.27e-1)" "unprognostic (1.76e-1)" "unprognostic (9.43e-2)" "unprognostic (1.31e-1)" "unprognostic (2.48e-1)" "unprognostic (5.69e-2)" "unprognostic (1.11e-1)" EYA2 EAB1 ENSG00000064655 "EYA transcriptional coactivator and phosphatase 2" O00167 20 46894624-47188844 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 52.3" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 546.5;Conjunctival goblet cells: 419.4;Endometrial glandular cells: 482.8;Prostatic hillock cells: 649.3;Respiratory basal cells: 780.6;Respiratory ionocytes: 497.8;Respiratory secretory cells: 500.3;Salivary basal cells: 743.2;Salivary duct cells: 806.3;Salivary ionocytes: 759.2;Salivary myoepithelial cells: 470.7" "Cell type enhanced" "Detected in all" "astrocyte: 352.0;eccentric medium spiny neuron: 217.0;fibroblast: 212.9" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 138.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 23.8" "Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA027024, HPA059291" Uncertain Supported Cytosol NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 20: Myeloma - Immune response" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 9 Cytosol "HPA027024: , HPA059291: " "unprognostic (2.62e-2)" "unprognostic (9.11e-2)" "unprognostic (2.17e-1)" "unprognostic (1.01e-1)" "unprognostic (3.58e-1)" "unprognostic (3.09e-1)" "unprognostic (3.10e-2)" "unprognostic (6.56e-3)" "unprognostic (1.01e-1)" "unprognostic (1.05e-1)" "unprognostic (1.49e-1)" "unprognostic (2.12e-2)" "unprognostic (5.17e-3)" "unprognostic (1.02e-1)" "unprognostic (1.92e-1)" "unprognostic (2.03e-1)" "unprognostic (3.50e-2)" "unprognostic (2.23e-1)" "unprognostic (2.48e-1)" "unprognostic (8.60e-2)" "unprognostic (2.22e-1)" "unprognostic (2.81e-1)" "unprognostic (1.21e-1)" "unprognostic (7.38e-2)" "unprognostic (3.05e-1)" "unprognostic (2.31e-1)" "unprognostic (1.42e-1)" "potential prognostic unfavorable (7.53e-5)" "unprognostic (2.58e-2)" EYA3 DKFZp686C132 ENSG00000158161 "EYA transcriptional coactivator and phosphatase 3" Q99504 1 27970344-28088637 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Renal connecting tubule cells: 493.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052432, HPA062889" Uncertain Enhanced Nucleoplasm,Centrosome Yes No "Cluster 16: Non-specific - Cell proliferation" "Cluster 39: Testis - Nuclear processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 11 Nucleoplasm Centrosome "HPA052432: , HPA062889: " "unprognostic (7.65e-3)" "unprognostic (1.85e-1)" "unprognostic (1.97e-1)" "unprognostic (8.32e-2)" "unprognostic (6.55e-2)" "unprognostic (4.18e-1)" "unprognostic (2.03e-1)" "unprognostic (1.23e-2)" "unprognostic (1.92e-2)" "unprognostic (3.50e-2)" "potential prognostic favorable (4.23e-6)" "unprognostic (3.54e-3)" "unprognostic (3.00e-3)" "potential prognostic unfavorable (6.92e-4)" "unprognostic (1.73e-3)" "unprognostic (1.74e-1)" "unprognostic (4.69e-2)" "unprognostic (3.13e-1)" "unprognostic (9.98e-2)" "unprognostic (3.14e-2)" "unprognostic (9.15e-2)" "unprognostic (6.22e-2)" "unprognostic (1.17e-2)" "unprognostic (5.78e-2)" "unprognostic (3.21e-2)" "unprognostic (5.57e-2)" "unprognostic (5.80e-2)" "unprognostic (1.41e-1)" "unprognostic (1.58e-1)" "unprognostic (4.80e-2)" "unprognostic (9.14e-3)" EYA4 "CMD1J, DFNA10" ENSG00000112319 "EYA transcriptional coactivator and phosphatase 4" O95677 6 133240514-133532128 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, Hydrolase, Protein phosphatase" "Cardiomyopathy, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 29.0;tongue: 18.7" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 414.8;Cardiomyocytes: 429.9;Choroid plexus epithelial cells: 475.1;Corticotrophs: 320.8;Ependymal cells: 821.1;Medullary thymic epithelial cells: 523.2;Myonuclei: 1095.3;Pituitary stem cells: 1750.9;Renal collecting duct principal cells: 717.4;Respiratory basal cells: 277.6;Thymic myoid cells: 311.4" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 414.3;ependymal cell: 957.0;LAMP5-LHX6 and Chandelier: 676.6" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 4.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells, Kidney - Fibroblasts, Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA004805, HPA038771, HPA038772" Enhanced Approved Nucleoplasm No NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 3: Choroid plexus - Cilium" "Cluster 5: Rhabdoid - Unknown function" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 10 Nucleoplasm "HPA004805: , HPA038771: , HPA038772: " "unprognostic (2.82e-1)" "unprognostic (2.08e-1)" "potential prognostic unfavorable (3.13e-4)" "unprognostic (1.41e-2)" "unprognostic (7.22e-2)" "unprognostic (7.32e-2)" "unprognostic (2.51e-2)" "unprognostic (2.00e-1)" "unprognostic (7.67e-2)" "unprognostic (6.91e-2)" "unprognostic (6.95e-2)" EYS "bA166P24.2, bA307F22.3, bA74E24.1, C6orf178, C6orf179, C6orf180, dJ1018A4.2, dJ303F19.1, EGFL10, EGFL11, RP25, SPAM" ENSG00000188107 "Eyes shut homolog" Q5T1H1 6 63719980-65707226 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Sensory transduction, Vision" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 37 "retina: 23.1" "Group enriched" "Detected in many" 12 "Cone photoreceptor cells: 6630.6;Rod photoreceptor cells: 4150.9" "Cell type enhanced" "Detected in all" "hippocampal CA4: 421.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.1" "Cancer enhanced" "Detected in some" "Rhabdoid: 2.4" "Testis - Early spermatids, Testis - Late spermatids" HPA027103 Uncertain "Plasma membrane,Cytosol,Flagellar centriole" "Secreted in other tissues" Other NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 42: Retina - Visual perception" "Cluster 37: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 79: Photoreceptor cells - Phototransduction" "Plasma membrane, Cytosol, Flagellar centriole" "HPA027103: " "unprognostic (1.23e-1)" "unprognostic (8.47e-2)" "potential prognostic favorable (8.44e-4)" "unprognostic (7.12e-3)" "unprognostic (3.39e-2)" "unprognostic (1.43e-1)" EZH1 "KIAA0388, KMT6B" ENSG00000108799 "Enhancer of zeste 1 polycomb repressive complex 2 subunit" Q92800 17 42700275-42745049 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 123.7" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 267.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005478, HPA077684" Supported Supported Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 79: Photoreceptor cells - Phototransduction" 15 Nucleoplasm "HPA005478: , HPA077684: " "unprognostic (1.23e-2)" "unprognostic (3.99e-1)" "unprognostic (5.24e-3)" "unprognostic (3.28e-1)" "unprognostic (5.41e-2)" "unprognostic (3.66e-3)" "unprognostic (2.72e-1)" "unprognostic (4.79e-2)" "unprognostic (5.33e-3)" "unprognostic (4.89e-2)" "validated prognostic favorable (3.55e-5)" "validated prognostic favorable (6.99e-5)" "unprognostic (8.37e-3)" "unprognostic (4.59e-2)" "unprognostic (1.72e-1)" "unprognostic (1.38e-2)" "unprognostic (8.97e-2)" "unprognostic (2.62e-1)" "unprognostic (4.84e-1)" "unprognostic (6.27e-3)" "unprognostic (2.14e-1)" "unprognostic (2.66e-3)" "unprognostic (3.15e-2)" "unprognostic (1.51e-2)" "unprognostic (1.71e-3)" "unprognostic (1.65e-3)" "unprognostic (1.20e-1)" "unprognostic (2.92e-2)" "unprognostic (3.87e-2)" "unprognostic (1.65e-1)" "unprognostic (8.19e-2)" EZH2 "ENX-1, EZH1, KMT6, KMT6A" ENSG00000106462 "Enhancer of zeste 2 polycomb repressive complex 2 subunit" Q15910 7 148807257-148884321 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 23.9;lymphoid tissue: 34.1;testis: 24.5" "Cell type enhanced" "Detected in all" "Erythrocyte progenitors: 263.2;Late primary spermatocytes: 222.2;Megakaryocyte progenitors: 167.3;Monocyte progenitors: 269.0;Neutrophil progenitors: 246.2;Respiratory deuterosomal cells: 180.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 7.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Mitotic cells (Colon), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009589, HPA029131" Enhanced Enhanced Nucleoplasm NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 39: Non-specific - Transcription" "Cluster 27: Non-specific - Cell proliferation" 275 Nucleoplasm "CAB009589: , HPA029131: " "unprognostic (2.39e-1)" "unprognostic (1.04e-1)" "unprognostic (3.10e-2)" "unprognostic (3.75e-3)" "unprognostic (2.57e-2)" "unprognostic (6.06e-2)" "unprognostic (1.57e-1)" "unprognostic (4.43e-2)" "unprognostic (2.72e-3)" "potential prognostic unfavorable (1.07e-4)" "unprognostic (1.21e-3)" "unprognostic (1.42e-2)" "potential prognostic unfavorable (5.10e-5)" "validated prognostic unfavorable (1.91e-7)" "validated prognostic unfavorable (2.43e-5)" "unprognostic (4.25e-3)" "unprognostic (2.68e-3)" "unprognostic (1.50e-2)" "unprognostic (8.93e-2)" "unprognostic (2.52e-3)" "unprognostic (8.84e-3)" "potential prognostic unfavorable (3.12e-4)" "unprognostic (4.68e-2)" "unprognostic (1.01e-3)" "unprognostic (2.65e-1)" "unprognostic (3.64e-1)" "unprognostic (9.03e-3)" "unprognostic (1.06e-3)" "unprognostic (1.92e-1)" "unprognostic (1.39e-1)" "unprognostic (1.27e-2)" EZHIP "CATACOMB, CXorf67" ENSG00000187690 "EZH inhibitory protein" Q86X51 X 51406948-51408843 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.7;testis: 5.8" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Testicular Germ Cell Tumor (TCGA): 18.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bone cancer: 1.9;Brain cancer: 1.0" "Testis - Spermatogonia" "HPA004003, HPA006128" Enhanced Enhanced Nucleoplasm NA NA "Cluster 67: Testis - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 51: Myeloma - Immunoglobulins" 5 Nucleoplasm "HPA004003: , HPA006128: " "unprognostic (3.98e-2)" "unprognostic (9.25e-2)" "unprognostic (3.42e-2)" "unprognostic (5.54e-2)" EZR VIL2 ENSG00000092820 Ezrin P15311 6 158765741-158819368 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell shape" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 2059.1;Esophageal apical cells: 2062.0;Ocular epithelial cells: 3071.0;Syncytiotrophoblasts: 2089.8;Urothelial cells: 2184.8" "Group enriched" "Detected in many" 4 "astrocyte: 190.9;choroid plexus epithelial cell: 490.9;ependymal cell: 300.3;leukocyte: 200.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal cortex cells, Skin - Keratinocyte (other), Spleen - B-cells (Spleen), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004035, HPA021616, CAB047324, CAB075739" Enhanced Supported "Plasma membrane" NA NA 33000000 "Cluster 16: Non-specific - Cell proliferation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 8: Immune cells - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 124 "Plasma membrane" "CAB004035: , CAB047324: , CAB075739: , HPA021616: " "unprognostic (3.75e-1)" "unprognostic (2.88e-3)" "unprognostic (1.63e-1)" "unprognostic (2.90e-2)" "unprognostic (4.11e-2)" "unprognostic (2.76e-1)" "unprognostic (4.30e-2)" "unprognostic (2.82e-1)" "unprognostic (6.87e-3)" "unprognostic (8.98e-2)" "potential prognostic favorable (1.21e-10)" "unprognostic (1.02e-3)" "potential prognostic favorable (1.01e-4)" "unprognostic (9.77e-3)" "unprognostic (6.42e-2)" "unprognostic (5.78e-2)" "unprognostic (2.01e-1)" "unprognostic (2.92e-1)" "unprognostic (2.44e-1)" "unprognostic (4.17e-2)" "unprognostic (2.71e-1)" "potential prognostic unfavorable (1.85e-4)" "unprognostic (2.15e-3)" "unprognostic (1.57e-1)" "unprognostic (1.28e-2)" "unprognostic (5.45e-2)" "unprognostic (2.22e-1)" "unprognostic (1.54e-1)" "unprognostic (2.54e-1)" "unprognostic (2.79e-1)" "unprognostic (2.72e-1)" F10 ENSG00000126218 "Coagulation factor X" P00742 13 113122799-113149529 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 149.7" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 95.1;Fibroblasts: 118.4;Hepatocytes: 234.7;Late primary spermatocytes: 57.1;Leydig cells: 188.4;Pancreatic islet cells: 287.8;Pericytes: 72.1;Peritubular myoid cells: 233.2" "Cell type enhanced" "Detected in many" "fibroblast: 49.8;pericyte: 28.0" "Cancer enriched" "Detected in many" 9 "Liver Hepatocellular Carcinoma (TCGA): 183.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Adrenocortical cancer: 6.9;liver cancer: 16.8" "Breast - Fibroblasts, Colon - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatocytes, Minor Salivary Gland - Fibroblasts, Pituitary gland - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblasts_1, Skin - Fibroblasts_2, Spleen - Fibroblasts_1, Spleen - Fibroblasts_2, Thyroid gland - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to blood" "Blood coagulation" NA NA 3400000000 "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 49: Hindbrain - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 108: Fibroblasts - ECM organization" 11 "unprognostic (1.38e-1)" "unprognostic (1.14e-1)" "unprognostic (1.65e-2)" "unprognostic (1.71e-3)" "unprognostic (1.31e-1)" "unprognostic (1.27e-1)" "unprognostic (1.54e-1)" "unprognostic (4.04e-1)" "unprognostic (3.01e-2)" "unprognostic (1.77e-1)" "unprognostic (3.78e-3)" "unprognostic (6.28e-2)" "unprognostic (5.64e-3)" "unprognostic (2.49e-3)" "unprognostic (5.69e-2)" "potential prognostic unfavorable (4.00e-4)" "unprognostic (1.88e-1)" "unprognostic (1.15e-1)" "unprognostic (3.99e-2)" "potential prognostic favorable (4.34e-5)" "unprognostic (4.45e-2)" "unprognostic (1.95e-2)" "unprognostic (1.78e-2)" "unprognostic (5.29e-2)" "unprognostic (6.38e-2)" "unprognostic (3.50e-2)" "unprognostic (3.61e-2)" "unprognostic (2.18e-2)" "unprognostic (3.01e-2)" F11 FXI ENSG00000088926 "Coagulation factor XI" P03951 4 186266189-186289681 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Heparin-binding, Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "liver: 227.2" "Cell type enhanced" "Detected in some" "Cholangiocytes: 11.9;Distal convoluted tubule cells: 47.4;Hepatocytes: 133.7;Loop of henle epithelial cells: 42.5;Pancreatic acinar cells: 22.5;Pancreatic duct cells: 11.8;pDCs: 13.6;Proximal tubule cells: 17.9;Renal connecting tubule cells: 13.4" "Cell type enriched" "Detected in some" 9 "midbrain-derived inhibitory: 33.8" "Cancer enriched" "Detected in some" 12 "Liver Hepatocellular Carcinoma (TCGA): 46.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "liver cancer: 1.8" "Kidney - Ascending Loop of Henle cells, Liver - Hepatocytes, Lung - Alveolar cells type 2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA039808 Approved Vesicles "Secreted to blood" "Blood coagulation" NA NA 1500000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 38: Sub-cortical - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" Vesicles "HPA039808: " "unprognostic (1.91e-2)" "potential prognostic favorable (4.99e-4)" "unprognostic (2.90e-3)" "validated prognostic favorable (1.19e-4)" "validated prognostic favorable (5.80e-6)" "unprognostic (3.74e-2)" "unprognostic (6.64e-2)" "unprognostic (6.81e-2)" "unprognostic (4.06e-2)" F11R "CD321, JAM-1, JAM-A, JAM1, JAMA, JCAM, PAM-1" ENSG00000158769 "F11 receptor" Q9Y624 1 160995211-161021343 "CD markers, Plasma proteins, Predicted membrane proteins" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 164.7;Esophageal apical cells: 314.2;Extravillous trophoblasts: 254.6;Ocular epithelial cells: 242.2;Pancreatic acinar cells: 173.6;Urothelial cells: 235.0" "Cell type enhanced" "Detected in many" "endothelial cell: 54.7;ependymal cell: 30.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "eosinophil: 166.2;neutrophil: 114.1" "Lineage enriched" "Detected in all" 5 "granulocytes: 166.2" "Cancer enhanced" "Detected in all" "testis cancer: 214.6" "Heart muscle - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004671, HPA043616, HPA061700" Enhanced Supported "Cell Junctions,Microtubules" NA NA 1800000 "Cluster 21: Neutrophils - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 30 Microtubules "Cell Junctions" "CAB004671: , HPA043616: , HPA061700: " "unprognostic (2.88e-1)" "unprognostic (1.56e-3)" "unprognostic (5.01e-2)" "unprognostic (1.28e-1)" "unprognostic (5.52e-2)" "unprognostic (2.86e-1)" "unprognostic (7.60e-2)" "unprognostic (2.79e-3)" "unprognostic (1.32e-1)" "unprognostic (4.69e-2)" "potential prognostic favorable (8.87e-6)" "unprognostic (5.87e-2)" "unprognostic (1.95e-1)" "unprognostic (1.82e-1)" "unprognostic (1.52e-1)" "unprognostic (1.59e-1)" "unprognostic (3.71e-2)" "unprognostic (1.82e-1)" "unprognostic (1.42e-1)" "unprognostic (1.59e-1)" "unprognostic (3.65e-2)" "potential prognostic unfavorable (4.26e-4)" "unprognostic (1.38e-1)" "unprognostic (4.38e-2)" "unprognostic (4.10e-3)" "unprognostic (1.35e-2)" "unprognostic (3.68e-1)" "unprognostic (9.89e-2)" "unprognostic (2.07e-1)" "unprognostic (1.22e-1)" "unprognostic (1.21e-1)" F12 ENSG00000131187 "Coagulation factor XII" P00748 5 177402133-177416583 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis" "Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 316 "liver: 593.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 48.9;Enteric transient amplifying cells: 50.9;Enterocytes: 59.6;Esophageal basal cells: 174.7;Esophageal suprabasal cells: 132.7;Gastric progenitor cells: 48.7;Hepatocytes: 618.3;Late spermatids: 62.8;Suprabasal keratinocytes: 64.8" "Cell type enhanced" "Detected in many" "hippocampal CA4: 19.9" "Cancer enriched" "Detected in many" 96 "Liver Hepatocellular Carcinoma (TCGA): 275.5" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "eosinophil: 1.7" "Lineage enhanced" "Detected in single" "granulocytes: 1.7" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA003825 Approved "Secreted to blood" "Blood coagulation" NA NA 1040000 10000000000 "Cluster 19: Eosinophils - Unknown function" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 93: Hepatocytes - Bile production & excretion" 43 "HPA003825: " "unprognostic (5.73e-2)" "unprognostic (4.24e-1)" "unprognostic (1.13e-3)" "unprognostic (8.13e-2)" "unprognostic (8.98e-3)" "unprognostic (8.33e-2)" "unprognostic (1.72e-1)" "unprognostic (2.39e-1)" "unprognostic (1.81e-2)" "unprognostic (8.65e-2)" "unprognostic (2.12e-1)" "validated prognostic favorable (8.62e-5)" "validated prognostic favorable (1.55e-4)" "unprognostic (3.36e-2)" "unprognostic (2.85e-1)" "unprognostic (2.65e-1)" "unprognostic (4.61e-1)" "unprognostic (3.83e-1)" "unprognostic (1.37e-1)" "unprognostic (7.12e-2)" F13A1 F13A ENSG00000124491 "Coagulation factor XIII A chain" P00488 6 6144084-6321013 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Acyltransferase, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 217.7;placenta: 459.5" "Group enriched" "Detected in many" 8 "Hofbauer cells: 3096.2;Macrophages: 1161.7;Megakaryocytes: 1242.5;Platelets: 2650.3" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 99.1;fibroblast: 174.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 141.3;myeloid DC: 179.8" "Group enriched" "Detected in many" 184 "dendritic cells: 179.8;granulocytes: 50.0;monocytes: 141.3" "Cancer enhanced" "Detected in some" "cervical cancer: 13.1;Leukemia: 20.7" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Lung - Macrophages, Minor Salivary Gland - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA001804, CAB002155" Enhanced "Secreted to blood" "Blood coagulation" NA NA 2500000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 8: Immune cells - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 15 "CAB002155: , HPA001804: " "unprognostic (1.58e-1)" "unprognostic (1.71e-1)" "unprognostic (3.05e-1)" "unprognostic (1.49e-2)" "unprognostic (1.69e-1)" "unprognostic (6.99e-3)" "unprognostic (6.41e-3)" "unprognostic (3.38e-3)" "unprognostic (4.55e-2)" "unprognostic (1.18e-1)" "unprognostic (2.02e-2)" "unprognostic (1.01e-1)" "unprognostic (3.27e-2)" "unprognostic (3.94e-2)" "unprognostic (3.04e-2)" "unprognostic (1.05e-2)" "unprognostic (8.60e-3)" "potential prognostic unfavorable (3.86e-4)" "unprognostic (1.59e-1)" "unprognostic (2.11e-2)" "unprognostic (1.15e-2)" "unprognostic (2.40e-2)" "unprognostic (1.31e-1)" "unprognostic (4.81e-1)" "unprognostic (1.46e-1)" "unprognostic (3.87e-2)" "unprognostic (1.90e-2)" "unprognostic (5.49e-3)" "unprognostic (1.76e-1)" "unprognostic (1.52e-1)" "unprognostic (1.30e-1)" F13B FXIIIB ENSG00000143278 "Coagulation factor XIII B chain" P05160 1 197038741-197067260 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 210 "liver: 187.2" "Cell type enriched" "Detected in some" 34 "Hepatocytes: 137.0" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 580 "Liver Hepatocellular Carcinoma (TCGA): 57.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA003827, HPA052139" Supported "Secreted to blood" "Blood coagulation" NA NA 7400000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 18: Liver cancer - Metabolism" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 1 "HPA003827: , HPA052139: " "potential prognostic favorable (6.42e-5)" "unprognostic (4.78e-2)" F2 ENSG00000180210 "Coagulation factor II, thrombin" P00734 11 46719196-46739506 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase, Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1206 "liver: 1138.4" "Cell type enriched" "Detected in some" 7 "Hepatocytes: 1119.0" "Low cell type specificity" "Detected in single" "Cancer enriched" "Detected in some" 76 "Liver Hepatocellular Carcinoma (TCGA): 827.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 10 "liver cancer: 64.3" "Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB016780, HPA051476, HPA054698" Enhanced "Secreted to blood" "Blood coagulation" NA NA 108000000000 69000000000 "Cluster 53: Liver - Plasma proteins" "Cluster 15: Non-specific - Transcription" "Cluster 18: Liver cancer - Metabolism" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 8 "CAB016780: , HPA051476: , HPA054698: " "validated prognostic unfavorable (1.23e-6)" "validated prognostic unfavorable (4.97e-4)" "unprognostic (1.43e-1)" "unprognostic (1.69e-3)" "potential prognostic unfavorable (1.80e-4)" "unprognostic (9.50e-3)" "unprognostic (4.13e-1)" F2R "CF2R, PAR-1, PAR1, TR" ENSG00000181104 "Coagulation factor II thrombin receptor" P25116 5 76716126-76735770 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Blood coagulation, Hemostasis" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 65.4" "Cell type enriched" "Detected in many" 4 "Platelets: 557.2" "Cell type enhanced" "Detected in many" "fibroblast: 35.2;leukocyte: 56.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 25.5" "Group enriched" "Detected in many" 14 "NK-cells: 7.0;T-cells: 25.5" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008973, CAB012962" Approved NA NA "Cluster 24: Non-specific - Transcription" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 46: Brainstem - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 47: Platelets - Hemostasis" 6 "CAB008973: , CAB012962: " "unprognostic (2.77e-1)" "unprognostic (3.04e-1)" "unprognostic (4.25e-2)" "unprognostic (3.49e-2)" "unprognostic (9.10e-2)" "unprognostic (7.49e-2)" "unprognostic (2.80e-2)" "unprognostic (1.66e-1)" "unprognostic (2.67e-1)" "unprognostic (1.20e-1)" "unprognostic (2.89e-3)" "unprognostic (1.49e-2)" "potential prognostic unfavorable (1.32e-5)" "unprognostic (8.59e-2)" "unprognostic (7.32e-2)" "unprognostic (6.94e-3)" "unprognostic (4.29e-3)" "unprognostic (3.47e-2)" "unprognostic (7.55e-2)" "unprognostic (3.85e-2)" "unprognostic (5.22e-3)" "unprognostic (2.28e-1)" "unprognostic (2.93e-1)" "unprognostic (4.85e-1)" "unprognostic (3.99e-1)" "unprognostic (5.85e-3)" "unprognostic (5.24e-2)" "unprognostic (9.34e-3)" "unprognostic (3.87e-1)" "unprognostic (4.13e-2)" "unprognostic (2.19e-1)" F2RL1 "GPR11, PAR2" ENSG00000164251 "F2R like trypsin receptor 1" P55085 5 76818933-76835315 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 55.6;stomach 1: 41.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 86.2;Colonocytes: 112.2;Endometrial glandular cells: 91.2;Enteric stem cells: 67.3;Enteric transient amplifying cells: 65.4;Enterocytes: 96.5;Epididymal efferent duct absorptive cells: 62.7;Foveolar cells: 141.7;Goblet cells: 69.1;Ocular epithelial cells: 104.3;Pancreatic duct cells: 77.6;Suprabasal keratinocytes: 121.8;Urothelial cells: 134.6" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 5.4;choroid plexus epithelial cell: 6.0;ependymal cell: 5.4" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "choroid plexus: 18.1" "Immune cell enhanced" "Detected in many" "neutrophil: 42.2" "Lineage enriched" "Detected in many" 4 "granulocytes: 42.2" "Cancer enhanced" "Detected in many" "Bile duct cancer: 184.1" "Colon - Colon enterocytes, Kidney - Macrophages, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Somatotropes, Skin - Keratinocyte (other), Spleen - Macrophages, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB012989, HPA014091" Approved Approved "Plasma membrane" NA Yes "Cluster 21: Neutrophils - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 3: Choroid plexus - Cilium" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 100: Stratified epithelial cells - Barrier functions" 82 "Plasma membrane" "CAB012989: , HPA014091: " "unprognostic (9.10e-2)" "unprognostic (6.12e-2)" "unprognostic (1.33e-1)" "unprognostic (6.73e-2)" "unprognostic (1.90e-2)" "unprognostic (2.99e-2)" "unprognostic (1.73e-1)" "unprognostic (2.12e-1)" "unprognostic (1.15e-3)" "unprognostic (1.84e-1)" "potential prognostic favorable (8.10e-14)" "unprognostic (4.34e-3)" "unprognostic (4.27e-2)" "unprognostic (1.04e-1)" "unprognostic (2.98e-3)" "potential prognostic unfavorable (6.06e-5)" "unprognostic (1.19e-2)" "unprognostic (8.06e-2)" "unprognostic (5.80e-2)" "unprognostic (4.89e-2)" "unprognostic (1.06e-1)" "unprognostic (1.77e-3)" "unprognostic (4.18e-1)" "unprognostic (2.14e-2)" "unprognostic (2.34e-2)" "unprognostic (1.16e-1)" "unprognostic (5.00e-2)" "unprognostic (1.04e-1)" "unprognostic (1.94e-1)" "unprognostic (9.19e-3)" "unprognostic (1.83e-1)" F2RL2 PAR3 ENSG00000164220 "Coagulation factor II thrombin receptor like 2" O00254 5 76615482-76623413 "G-protein coupled receptors, Predicted membrane proteins" "Blood coagulation, Hemostasis" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 6.4" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 6.2;Early spermatids: 5.6;Fibroblasts: 5.8;Hematopoietic stem cells: 14.6;Hepatic stellate cells: 6.5;Innate lymphoid cells: 6.0;Macrophages: 5.8;NK-cells: 9.7;Retinal pigment epithelial cells: 17.1;Rod photoreceptor cells: 16.8;Schwann cells: 8.8;T-cells: 7.1;Thymocytes: 14.4;Tuft cells: 11.5" "Group enriched" "Detected in some" 4 "astrocyte: 3.2;ependymal cell: 1.6;fibroblast: 1.6;leukocyte: 3.3;MGE interneuron: 1.5;midbrain-derived inhibitory: 4.8" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 15.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "basophil: 10.3" "Lineage enriched" "Detected in many" 9 "granulocytes: 10.3" "Cancer enhanced" "Detected in many" "Rhabdoid: 36.3" "Colon - Enteric glia cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 42: Retina - Visual perception" "Cluster 46: Brainstem - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 1 "unprognostic (4.01e-1)" "unprognostic (1.31e-2)" "unprognostic (9.33e-2)" "unprognostic (6.77e-2)" "unprognostic (7.31e-3)" "unprognostic (2.77e-1)" "unprognostic (3.79e-2)" "unprognostic (7.18e-3)" "unprognostic (4.20e-2)" "unprognostic (7.93e-2)" "unprognostic (1.07e-1)" "potential prognostic unfavorable (5.17e-5)" "unprognostic (1.77e-1)" "unprognostic (4.98e-3)" "unprognostic (3.17e-1)" "unprognostic (1.05e-1)" "unprognostic (2.05e-1)" "unprognostic (1.07e-1)" "unprognostic (2.64e-1)" "unprognostic (3.53e-1)" "unprognostic (4.11e-2)" "unprognostic (5.90e-3)" "unprognostic (6.13e-2)" "unprognostic (1.25e-1)" F2RL3 PAR4 ENSG00000127533 "F2R like thrombin or trypsin receptor 3" Q96RI0 19 16888999-16892606 "G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Blood coagulation, Hemostasis" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 18.9;breast: 19.0;lung: 33.0;thyroid gland: 19.3" "Group enriched" "Detected in some" 4 "Lymphatic endothelial cells: 48.9;Megakaryocytes: 61.8;Platelets: 108.8;Vascular endothelial cells: 97.2" "Cell type enhanced" "Detected in single" "endothelial cell: 1.1" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 15.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Leukemia: 10.6" "Testis - Sertoli cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA031401, HPA042340" Supported "Plasma membrane" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 48: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "Plasma membrane" "HPA031401: , HPA042340: " "unprognostic (2.84e-1)" "unprognostic (3.48e-1)" "unprognostic (5.83e-2)" "unprognostic (7.16e-2)" "unprognostic (1.49e-1)" "unprognostic (2.26e-1)" "unprognostic (2.69e-1)" "unprognostic (1.80e-1)" "unprognostic (1.95e-2)" "unprognostic (4.14e-1)" "validated prognostic favorable (4.41e-8)" "validated prognostic favorable (2.50e-6)" "unprognostic (3.23e-2)" "unprognostic (1.72e-1)" "unprognostic (6.54e-2)" "unprognostic (1.38e-2)" "potential prognostic unfavorable (7.64e-4)" "unprognostic (2.13e-2)" "unprognostic (1.17e-1)" "unprognostic (2.38e-1)" "unprognostic (5.08e-2)" "unprognostic (1.05e-1)" "unprognostic (9.91e-2)" "unprognostic (2.67e-1)" "potential prognostic favorable (1.80e-5)" "unprognostic (6.66e-3)" "unprognostic (1.01e-1)" "unprognostic (2.92e-1)" "unprognostic (4.51e-2)" F3 "CD142, TF" ENSG00000117525 "Coagulation factor III, tissue factor" P13726 1 94529173-94541759 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Blood coagulation, Hemostasis" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 814.0;Alveolar cells type 2: 428.7;Conjunctival goblet cells: 927.2;Endometrial secretory cells: 544.8;Epididymal basal cells: 469.8;Müller glia: 426.2;Ocular epithelial cells: 1205.2;Pancreatic acinar cells: 965.0;Peritubular myoid cells: 763.1;Respiratory basal cells: 686.2;Respiratory deuterosomal cells: 869.7;Respiratory secretory cells: 950.2" "Cell type enhanced" "Detected in many" "astrocyte: 248.5;fibroblast: 443.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 655.6" "Kidney - Podocytes, Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009438, HPA049292, HPA069132" Uncertain Approved Vesicles "Secreted to blood" "Blood coagulation" NA NA 603000 "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 12 Vesicles "CAB009438: , HPA049292: , HPA069132: " "unprognostic (1.24e-1)" "unprognostic (5.40e-2)" "unprognostic (2.52e-1)" "unprognostic (2.73e-2)" "unprognostic (4.70e-2)" "unprognostic (1.35e-1)" "unprognostic (3.11e-2)" "potential prognostic unfavorable (7.75e-5)" "unprognostic (4.84e-3)" "unprognostic (1.44e-3)" "potential prognostic unfavorable (2.57e-4)" "unprognostic (3.19e-2)" "unprognostic (1.61e-2)" "unprognostic (5.22e-2)" "unprognostic (4.06e-2)" "unprognostic (7.62e-2)" "unprognostic (1.06e-1)" "unprognostic (3.99e-1)" "unprognostic (1.71e-1)" "unprognostic (4.70e-2)" "unprognostic (1.43e-1)" "potential prognostic unfavorable (1.26e-5)" "unprognostic (2.62e-2)" "unprognostic (2.11e-1)" "unprognostic (6.14e-2)" "unprognostic (3.20e-2)" "unprognostic (3.77e-1)" "unprognostic (5.69e-2)" "unprognostic (1.18e-1)" "unprognostic (1.55e-1)" "unprognostic (8.97e-2)" F5 ENSG00000198734 "Coagulation factor V" P12259 1 169511951-169586588 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "choroid plexus: 77.1;liver: 164.8;placenta: 44.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 163.8;Cholangiocytes: 72.0;Choroid plexus epithelial cells: 441.9;Cytotrophoblasts: 122.6;Epididymal efferent duct ciliated cells: 103.7;Hepatocytes: 487.0;Neutrophils: 312.3;Podocytes: 90.9;Syncytiotrophoblasts: 73.1" "Cell type enriched" "Detected in many" 7 "choroid plexus epithelial cell: 358.5" "Cancer enriched" "Detected in many" 6 "Liver Hepatocellular Carcinoma (TCGA): 78.0" "Region enriched" "Detected in all" 22 "choroid plexus: 306.3" "Group enriched" "Detected in some" 4 "classical monocyte: 4.1;eosinophil: 8.1;neutrophil: 7.0;T-reg: 6.2" "Group enriched" "Detected in many" 13 "granulocytes: 8.1;monocytes: 4.1;T-cells: 6.2" "Cancer enhanced" "Detected in many" "liver cancer: 17.9" "Kidney - Podocytes, Liver - Hepatocytes, Lung - Neutrophils_2, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Urothelial cells, Skin - Eccrine sweat gland cells, Spleen - Neutrophils_2, Stomach - Gastric mucous cells, Testis - Early spermatids" "Group enriched" "Detected in many" 5 "basal ganglia: 2.7;hippocampal formation: 6.6;pons and medulla: 4.4;thalamus: 5.5" "Group enriched" "Detected in all" 7 "amygdala: 53.1;basal ganglia: 46.2;cerebral cortex: 89.3;hippocampal formation: 80.9;olfactory bulb: 37.0" HPA002036 Approved "Golgi apparatus" "Secreted to blood" "Blood coagulation" NA NA 7670000000 5500000000 "Cluster 7: Non-specific - Innate immune response" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 36: Choroid plexus - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 4 "Golgi apparatus" "HPA002036: " "unprognostic (1.18e-1)" "unprognostic (1.31e-1)" "unprognostic (2.79e-1)" "unprognostic (5.12e-2)" "unprognostic (1.69e-1)" "unprognostic (1.84e-1)" "unprognostic (2.60e-2)" "unprognostic (1.72e-1)" "potential prognostic unfavorable (7.66e-5)" "potential prognostic favorable (9.55e-4)" "unprognostic (3.33e-1)" "unprognostic (2.70e-2)" "unprognostic (2.41e-2)" "unprognostic (1.70e-2)" "unprognostic (1.38e-1)" "unprognostic (2.70e-2)" "unprognostic (3.66e-2)" "unprognostic (7.12e-2)" "unprognostic (3.54e-2)" "unprognostic (9.36e-2)" "unprognostic (3.92e-1)" "unprognostic (1.42e-3)" "unprognostic (5.88e-2)" "unprognostic (3.13e-1)" "unprognostic (6.90e-2)" F7 ENSG00000057593 "Coagulation factor VII" P08709 13 113105788-113120685 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 95 "liver: 128.6" "Cell type enriched" "Detected in some" 22 "Hepatocytes: 176.5" "Cell type enhanced" "Detected in some" "mammillary body: 1.2" "Cancer enriched" "Detected in some" 15 "Liver Hepatocellular Carcinoma (TCGA): 63.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 3.0;liver cancer: 8.7" "Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" "Blood coagulation" NA NA 351000000 200000000 "Cluster 53: Liver - Plasma proteins" "Cluster 1: Neurons - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 93: Hepatocytes - Bile production & excretion" 3 "unprognostic (5.69e-2)" "unprognostic (7.46e-2)" "unprognostic (1.38e-1)" "potential prognostic favorable (3.40e-5)" "unprognostic (2.90e-3)" "unprognostic (1.50e-1)" "unprognostic (3.37e-1)" "unprognostic (1.16e-1)" "unprognostic (1.60e-1)" F8 "DXS1253E, F8C, FVIII, HEMA" ENSG00000185010 "Coagulation factor VIII" P00451 X 154835788-155026940 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase, Blood coagulation, Hemostasis" "Disease variant, FDA approved drug targets, Hemophilia, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 51.1" "Group enriched" "Detected in many" 6 "Lymphatic endothelial cells: 212.8;Sertoli cells: 83.9;Vascular endothelial cells: 234.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 33.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" CAB018777 Enhanced "Secreted to blood" "Blood coagulation" NA NA 32000000 "Cluster 33: Non-specific - ATP binding" "Cluster 35: Non-specific - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 2 "CAB018777: " "unprognostic (1.45e-1)" "unprognostic (1.26e-1)" "unprognostic (2.21e-1)" "unprognostic (1.81e-2)" "unprognostic (5.87e-3)" "unprognostic (1.52e-2)" "unprognostic (8.58e-2)" "unprognostic (1.14e-1)" "unprognostic (1.58e-1)" "unprognostic (1.91e-1)" "potential prognostic favorable (7.94e-10)" "unprognostic (2.34e-3)" "unprognostic (7.71e-2)" "unprognostic (1.82e-2)" "unprognostic (3.51e-3)" "unprognostic (2.86e-2)" "unprognostic (1.38e-1)" "unprognostic (1.41e-1)" "unprognostic (1.28e-2)" "unprognostic (2.00e-1)" "unprognostic (1.11e-1)" "unprognostic (1.13e-1)" "unprognostic (6.08e-2)" "unprognostic (9.94e-2)" "unprognostic (3.16e-1)" "unprognostic (1.12e-1)" "unprognostic (1.91e-1)" "unprognostic (6.20e-3)" "unprognostic (4.84e-2)" "unprognostic (1.68e-2)" "unprognostic (8.40e-2)" F8A1 "DXS522E, F8A" ENSG00000288722 "Coagulation factor VIII associated 1" P23610 X 154886355-154888061 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 36: Non-specific - mRNA processing" "Cluster 97: Non-specific - Cellular respiration" 3 F8A2 ENSG00000288709 "Coagulation factor VIII associated 2" P23610 X 155382095-155383801 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 8.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "eosinophil: 1.5" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.5" "Low cancer specificity" "Detected in many" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 76: Non-specific - Metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 30: Non-specific - Gene expression regulation" 1 F8A3 ENSG00000277150 "Coagulation factor VIII associated 3" P23610 X 155456914-155458620 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "eosinophil: 1.5" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.5" "Low cancer specificity" "Detected in many" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 30: Non-specific - Gene expression regulation" 1 "unprognostic (7.87e-3)" "unprognostic (1.81e-1)" "unprognostic (9.63e-3)" "unprognostic (5.62e-3)" "unprognostic (9.95e-2)" "unprognostic (3.26e-1)" "unprognostic (1.15e-1)" "unprognostic (2.54e-1)" "unprognostic (4.67e-2)" "unprognostic (8.42e-2)" "unprognostic (7.43e-2)" "unprognostic (1.00e-2)" "unprognostic (1.52e-1)" "unprognostic (5.37e-2)" "unprognostic (5.48e-2)" "unprognostic (3.03e-1)" "unprognostic (1.70e-2)" "unprognostic (5.00e-2)" "unprognostic (4.93e-1)" "unprognostic (1.52e-1)" "unprognostic (2.06e-1)" "unprognostic (1.14e-1)" "unprognostic (1.62e-2)" "unprognostic (3.05e-1)" "unprognostic (8.79e-3)" "unprognostic (3.56e-2)" F9 FIX ENSG00000101981 "Coagulation factor IX" P00740 X 139530739-139563459 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets, Hemophilia, Thrombophilia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 2787 "liver: 659.1" "Cell type enriched" "Detected in some" 104 "Hepatocytes: 677.2" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 823 "Liver Hepatocellular Carcinoma (TCGA): 82.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" "Blood coagulation" NA NA 3100000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" "unprognostic (1.65e-3)" "potential prognostic favorable (3.31e-5)" FA2H "FAAH, FAXDC1, FLJ25287, SPG35" ENSG00000103089 "Fatty acid 2-hydroxylase" Q7L5A8 16 74712955-74774831 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Sphingolipid metabolism" Oxidoreductase "Disease variant, Hereditary spastic paraplegia, Leukodystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 182.4;stomach 1: 57.6" "Cell type enhanced" "Detected in many" "Colonocytes: 222.3;Foveolar cells: 556.4;Goblet cells: 161.2;Ocular epithelial cells: 211.0;Oligodendrocytes: 472.0;Pancreatic acinar cells: 234.0;Prostatic club cells: 256.6;Prostatic hillock cells: 353.2;Urothelial cells: 808.3" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 396.0;oligodendrocyte: 572.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells (progenitors), Liver - Cholangiocytes, Lung - Alveolar cells type 2, Skin - Sebaceous gland cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056614, HPA077840" Approved Uncertain "Nuclear membrane" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 69: Urothelial cells - Basic cellular functions" 34 "Nuclear membrane" "HPA056614: , HPA077840: " "unprognostic (3.75e-3)" "unprognostic (5.37e-2)" "unprognostic (4.63e-2)" "unprognostic (5.89e-2)" "unprognostic (3.28e-1)" "unprognostic (2.12e-2)" "unprognostic (1.64e-1)" "unprognostic (2.78e-2)" "unprognostic (7.25e-2)" "unprognostic (2.32e-1)" "unprognostic (1.06e-2)" "unprognostic (3.54e-2)" "unprognostic (6.50e-3)" "unprognostic (1.46e-3)" "unprognostic (5.10e-3)" "potential prognostic unfavorable (7.74e-4)" "unprognostic (2.58e-1)" "unprognostic (6.12e-2)" "unprognostic (7.02e-3)" "unprognostic (7.30e-2)" "potential prognostic unfavorable (4.04e-4)" "unprognostic (5.42e-2)" "unprognostic (7.24e-2)" "unprognostic (5.78e-2)" "unprognostic (1.30e-2)" "unprognostic (8.74e-2)" "unprognostic (1.16e-1)" "unprognostic (3.63e-3)" "unprognostic (1.70e-2)" FAAH FAAH-1 ENSG00000117480 "Fatty acid amide hydrolase" O00519 1 46394317-46413848 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 84.5;Late primary spermatocytes: 157.1;Late spermatids: 222.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 106.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 29.2" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "prostate cancer: 32.7" "Adipose visceral - Adipocytes (Visceral), Breast - Breast glandular cells, Breast - Breast glandular cells, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007425 Approved Approved Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 30: White matter - Myelination" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 6 Cytosol "HPA007425: " "unprognostic (1.78e-2)" "unprognostic (1.13e-1)" "unprognostic (1.74e-2)" "unprognostic (7.69e-2)" "unprognostic (5.72e-3)" "unprognostic (6.15e-3)" "unprognostic (7.00e-2)" "unprognostic (1.73e-2)" "unprognostic (1.23e-1)" "unprognostic (3.89e-3)" "validated prognostic favorable (7.86e-8)" "validated prognostic favorable (3.65e-4)" "potential prognostic favorable (1.51e-7)" "unprognostic (4.52e-1)" "potential prognostic favorable (1.66e-5)" "potential prognostic favorable (5.21e-4)" "unprognostic (2.81e-1)" "unprognostic (1.58e-2)" "unprognostic (3.76e-1)" "unprognostic (2.67e-2)" "unprognostic (2.50e-1)" "unprognostic (2.42e-2)" "unprognostic (2.03e-1)" "unprognostic (3.21e-1)" "unprognostic (1.87e-2)" "unprognostic (7.55e-2)" "unprognostic (1.70e-2)" "potential prognostic favorable (1.88e-4)" "unprognostic (3.50e-1)" "unprognostic (2.91e-3)" "unprognostic (6.68e-2)" FAAH2 "AMDD, FAAH-2, FLJ31204, RP11-479E16.1" ENSG00000165591 "Fatty acid amide hydrolase 2" Q6GMR7 X 57286706-57489193 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Lactotrophs: 363.3;Pancreatic acinar cells: 457.9;Plasma cells: 303.2;Prostatic glandular cells: 293.6;Somatotrophs: 413.0;Thyrotrophs: 363.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 16.7" "Lineage enriched" "Detected in many" 9 "T-cells: 16.7" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Lactotropes, Skin - Keratinocyte (other)" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 78: Plasma cells - Antibody production & ER-stress response" "unprognostic (1.96e-1)" "unprognostic (6.30e-2)" "unprognostic (4.13e-2)" "unprognostic (2.19e-1)" "unprognostic (1.55e-1)" "unprognostic (2.57e-1)" "unprognostic (3.26e-2)" "unprognostic (1.10e-1)" "unprognostic (8.58e-2)" "validated prognostic favorable (4.41e-10)" "validated prognostic favorable (7.23e-5)" "unprognostic (1.84e-2)" "unprognostic (5.53e-2)" "unprognostic (1.75e-2)" "unprognostic (1.74e-1)" "unprognostic (2.25e-1)" "unprognostic (9.88e-2)" "unprognostic (8.98e-2)" "unprognostic (1.31e-1)" "unprognostic (8.84e-2)" "unprognostic (5.03e-2)" "unprognostic (3.57e-2)" "unprognostic (2.28e-1)" "potential prognostic favorable (2.47e-4)" "unprognostic (3.76e-1)" "unprognostic (3.66e-3)" "unprognostic (1.05e-1)" "unprognostic (5.67e-3)" "unprognostic (1.65e-1)" FAAP100 "C17orf70, FLJ22175" ENSG00000185504 "FA core complex associated protein 100" Q0VG06 17 81539885-81553961 "Essential proteins, Predicted intracellular proteins" "DNA damage, DNA repair" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023954, HPA024626, HPA026532" Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 31 Nucleoplasm Cytosol "HPA023954: , HPA024626: , HPA026532: " "unprognostic (7.37e-3)" "unprognostic (7.48e-2)" "unprognostic (1.39e-1)" "unprognostic (4.01e-2)" "unprognostic (6.10e-2)" "unprognostic (1.47e-1)" "unprognostic (9.17e-2)" "unprognostic (3.36e-1)" "unprognostic (1.12e-3)" "potential prognostic unfavorable (8.41e-7)" "unprognostic (1.27e-2)" "unprognostic (5.04e-2)" "unprognostic (8.17e-3)" "unprognostic (1.88e-1)" "unprognostic (5.13e-2)" "unprognostic (2.22e-1)" "unprognostic (5.62e-2)" "unprognostic (4.77e-2)" "unprognostic (5.54e-3)" "unprognostic (1.15e-3)" "unprognostic (1.22e-1)" "unprognostic (1.04e-1)" "unprognostic (4.41e-3)" "unprognostic (1.92e-2)" "unprognostic (1.17e-1)" "unprognostic (2.44e-1)" "unprognostic (5.51e-1)" "unprognostic (7.37e-2)" "unprognostic (1.25e-1)" FAAP20 "C1orf86, FLJ31031" ENSG00000162585 "FA core complex associated protein 20" Q6NZ36 1 2184461-2212720 "Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 617.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038829 Uncertain Supported "Nucleoplasm,Nuclear bodies,Cell Junctions" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 15 Nucleoplasm "Nuclear bodies, Cell Junctions" "HPA038829: " "unprognostic (6.70e-2)" "unprognostic (2.42e-1)" "unprognostic (3.28e-2)" "unprognostic (2.29e-1)" "unprognostic (2.04e-1)" "unprognostic (1.18e-1)" "unprognostic (1.60e-2)" "unprognostic (1.46e-1)" "unprognostic (5.23e-2)" "unprognostic (1.12e-3)" "unprognostic (1.10e-1)" "unprognostic (1.42e-1)" "potential prognostic unfavorable (2.34e-4)" "unprognostic (3.21e-2)" "unprognostic (1.03e-1)" "unprognostic (3.38e-2)" "unprognostic (1.65e-2)" "unprognostic (1.83e-1)" "unprognostic (8.64e-2)" "unprognostic (1.24e-3)" "unprognostic (3.64e-2)" "unprognostic (1.56e-1)" "unprognostic (4.32e-2)" "unprognostic (2.46e-2)" "unprognostic (4.19e-1)" "unprognostic (2.63e-2)" "unprognostic (1.50e-1)" "unprognostic (3.38e-2)" "unprognostic (2.82e-1)" FAAP24 "C19orf40, FLJ46828, MGC32020" ENSG00000131944 "FA core complex associated protein 24" Q9BTP7 19 32972209-32978229 "Essential proteins, Predicted intracellular proteins" "DNA damage, DNA repair" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 14.6;Early primary spermatocytes: 12.8;Extravillous trophoblasts: 19.8;Late primary spermatocytes: 42.2;Late spermatids: 17.6;Migrating cytotrophoblasts: 13.0;Oocytes: 13.8" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041168 Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 11: White matter - Signal transduction" "Cluster 4: Non-specific - Transcription" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 8 Nucleoplasm Vesicles "HPA041168: " "unprognostic (2.68e-2)" "unprognostic (1.85e-1)" "unprognostic (6.48e-2)" "unprognostic (5.57e-2)" "unprognostic (3.07e-2)" "unprognostic (3.67e-2)" "unprognostic (2.78e-1)" "unprognostic (4.86e-1)" "potential prognostic unfavorable (7.83e-6)" "validated prognostic unfavorable (1.68e-8)" "validated prognostic unfavorable (4.27e-4)" "unprognostic (2.03e-2)" "unprognostic (1.95e-3)" "unprognostic (1.59e-3)" "unprognostic (2.24e-2)" "unprognostic (1.04e-1)" "unprognostic (1.86e-1)" "unprognostic (5.52e-2)" "unprognostic (2.43e-1)" "unprognostic (9.45e-3)" "unprognostic (2.04e-3)" "unprognostic (8.35e-2)" "unprognostic (7.35e-2)" "unprognostic (1.87e-2)" "unprognostic (1.16e-1)" "unprognostic (1.04e-1)" "unprognostic (1.80e-1)" "unprognostic (2.43e-2)" "unprognostic (2.13e-2)" FABP1 L-FABP ENSG00000163586 "Fatty acid binding protein 1" P07148 2 88122982-88128062 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 12 "intestine: 5139.5;liver: 12176.2" "Cell type enhanced" "Detected in some" "Colonocytes: 24611.3;Enteric transient amplifying cells: 5231.9;Enterocytes: 14089.0;Hepatocytes: 5907.7" "Cell type enhanced" "Detected in single" "Bergmann glia: 1.1" "Group enriched" "Detected in many" 13 "Colon Adenocarcinoma (TCGA): 1875.4;Liver Hepatocellular Carcinoma (TCGA): 3548.7;Rectum Adenocarcinoma (TCGA): 2030.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 408.0;colorectal cancer: 909.1;liver cancer: 309.9" "Colon - Colon enterocytes, Kidney - Proximal tubular cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB002305, HPA028275" Enhanced Approved Nucleoplasm,Cytosol NA NA 35000000 "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 3 "Nucleoplasm, Cytosol" "CAB002305: , HPA028275: " "unprognostic (3.14e-1)" "potential prognostic favorable (9.93e-4)" "potential prognostic favorable (1.49e-5)" "unprognostic (7.38e-3)" "unprognostic (1.19e-1)" "unprognostic (2.28e-2)" "unprognostic (1.16e-1)" "unprognostic (2.41e-1)" "unprognostic (1.99e-2)" "unprognostic (2.50e-1)" "unprognostic (4.77e-2)" "unprognostic (3.06e-2)" "unprognostic (8.99e-1)" "unprognostic (5.37e-2)" "unprognostic (1.18e-1)" "unprognostic (4.96e-1)" FABP12 ENSG00000197416 "Fatty acid binding protein 12" A6NFH5 8 81524981-81590139 "Metabolic proteins, Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "retina: 52.1" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 163.5;Early spermatids: 118.8;Esophageal basal cells: 47.9;Esophageal suprabasal cells: 58.2;Late primary spermatocytes: 38.9;Late spermatids: 207.1;Rod photoreceptor cells: 314.9" "Cell type enriched" "Detected in single" 4 "deep-layer near-projecting: 1.6" "Cancer enhanced" "Detected in single" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pituitary gland - Corticotropes, Skin - Inner root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" HPA044041 Enhanced NA NA "Cluster 42: Retina - Visual perception" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 79: Photoreceptor cells - Phototransduction" "HPA044041: " "unprognostic (1.07e-1)" FABP2 I-FABP ENSG00000145384 "Fatty acid binding protein 2" P12104 4 119317250-119322138 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 172 "intestine: 517.8" "Cell type enriched" "Detected in some" 12 "Enterocytes: 5633.9" "Cell type enriched" "Detected in single" 22 "choroid plexus epithelial cell: 8.2" "Group enriched" "Detected in some" 8 "Colon Adenocarcinoma (TCGA): 5.5;Pancreatic Adenocarcinoma (TCGA): 2.6;Rectum Adenocarcinoma (TCGA): 4.6;Stomach Adenocarcinoma (TCGA): 4.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 1.6;neutrophil: 4.2" "Lineage enriched" "Detected in single" 9 "granulocytes: 4.2" "Group enriched" "Detected in some" 5 "Bile duct cancer: 2.0;colorectal cancer: 1.8;Gastric cancer: 1.1" "Colon - Colon enterocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA034607, CAB047325, CAB047326" Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" NA NA 710000 "Cluster 35: Neutrophils - Protein binding" "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 9: Non-specific - Receptor signaling" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 1: Enterocytes - Absorption and Digestion" 2 "Actin filaments, Cytosol" "Plasma membrane" "CAB047325: , CAB047326: , HPA034607: " "unprognostic (5.26e-2)" "unprognostic (6.08e-2)" "unprognostic (3.15e-1)" "unprognostic (1.05e-1)" "unprognostic (5.42e-2)" "unprognostic (1.52e-3)" "unprognostic (1.29e-1)" FABP3 "FABP11, H-FABP, MDGI, O-FABP" ENSG00000121769 "Fatty acid binding protein 3" P05413 1 31365253-31376850 "Candidate cardiovascular disease genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 12 "heart muscle: 1397.8;skeletal muscle: 525.2;tongue: 1347.3" "Cell type enriched" "Detected in many" 16 "Breast lactating cells: 6817.2" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in all" 5 "Kidney Chromophobe (TCGA): 83.7;Kidney Renal Clear Cell Carcinoma (TCGA): 42.5;Kidney Renal Papillary Cell Carcinoma (TCGA): 50.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Pituitary gland - Gonadotropes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017830, HPA055754" Enhanced Uncertain "Golgi apparatus,Plasma membrane,Focal adhesion sites" NA NA 5600000 "Cluster 41: Striated muscle - Muscle contraction" "Cluster 24: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 4: Breast lactating luminal cells - Lactation" 3 "Focal adhesion sites" "Golgi apparatus, Plasma membrane" "CAB017830: , HPA055754: " "unprognostic (9.40e-2)" "unprognostic (9.21e-2)" "unprognostic (7.63e-2)" "unprognostic (3.61e-2)" "unprognostic (2.47e-3)" "unprognostic (7.15e-2)" "unprognostic (6.13e-3)" "unprognostic (2.11e-2)" "unprognostic (2.16e-2)" "unprognostic (1.58e-1)" "potential prognostic favorable (1.43e-4)" "unprognostic (2.03e-2)" "unprognostic (1.05e-2)" "potential prognostic unfavorable (5.96e-4)" "unprognostic (2.48e-1)" "unprognostic (3.74e-2)" "unprognostic (1.42e-1)" "unprognostic (3.02e-1)" "unprognostic (1.90e-1)" "unprognostic (1.31e-2)" "unprognostic (7.21e-2)" "unprognostic (1.86e-1)" "unprognostic (2.54e-1)" "unprognostic (4.90e-3)" "unprognostic (3.40e-3)" "unprognostic (2.70e-1)" "unprognostic (1.38e-1)" "unprognostic (4.50e-3)" "unprognostic (3.38e-1)" "unprognostic (4.35e-2)" "unprognostic (2.03e-2)" FABP4 "A-FABP, aP2" ENSG00000170323 "Fatty acid binding protein 4" P15090 8 81478419-81483236 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "adipose tissue: 3555.6;breast: 2416.5" "Cell type enhanced" "Detected in many" "Adipocytes: 1143.4;Lymphatic endothelial cells: 944.3;Macrophages: 285.3;Pericytes: 1116.7;Urothelial cells: 1743.6;Vascular endothelial cells: 1669.2;Vascular smooth muscle cells: 342.0" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 21.2;pericyte: 6.8" "Group enriched" "Detected in many" 5 "Bladder Urothelial Carcinoma (TCGA): 50.2;Breast Invasive Carcinoma (TCGA): 46.3;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 90.0;Head and Neck Squamous Cell Carcinoma (TCGA): 75.5" "Region enriched" "Detected in some" 10 "choroid plexus: 71.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Bladder cancer: 168.0;Rhabdoid: 56.8" "Adipose subcutaneous - Adipocytes (Subcutaneous), Colon - Endothelial cells, Minor Salivary Gland - Adipocytes (Minor salivary gland), Testis - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA002188, CAB024961, CAB080201" Enhanced Approved Nucleoplasm,Cytosol NA NA 19000000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 36: Choroid plexus - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 5 "Nucleoplasm, Cytosol" "CAB024961: , CAB080201: , HPA002188: " "unprognostic (1.24e-1)" "unprognostic (8.56e-2)" "unprognostic (7.61e-3)" "potential prognostic unfavorable (3.03e-4)" "unprognostic (8.15e-3)" "unprognostic (1.68e-1)" "unprognostic (2.11e-1)" "unprognostic (3.15e-2)" "unprognostic (4.04e-3)" "unprognostic (1.66e-1)" "potential prognostic favorable (8.60e-5)" "unprognostic (3.44e-2)" "potential prognostic favorable (4.95e-4)" "unprognostic (3.97e-3)" "unprognostic (1.68e-1)" "unprognostic (1.33e-1)" "unprognostic (5.63e-3)" "unprognostic (2.29e-2)" "unprognostic (4.19e-1)" "unprognostic (1.36e-1)" "unprognostic (1.14e-1)" "unprognostic (3.29e-1)" "unprognostic (3.90e-2)" "unprognostic (1.79e-2)" "unprognostic (1.55e-1)" "unprognostic (1.42e-3)" "unprognostic (9.99e-3)" "unprognostic (1.87e-1)" FABP5 "E-FABP, KFABP, PA-FABP" ENSG00000164687 "Fatty acid binding protein 5" Q01469 8 81280536-81284777 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Lipid transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 2768.1;esophagus: 4866.2;vagina: 3490.8" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 4150.4;Esophageal basal cells: 7537.5;Esophageal suprabasal cells: 12602.8;Ocular epithelial cells: 4932.8;Suprabasal keratinocytes: 3004.1;Urothelial cells: 1527.8" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 142.8" "Cancer enhanced" "Detected in all" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 2964.6;Head and Neck Squamous Cell Carcinoma (TCGA): 4902.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Macrophages, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017831, CAB040577, HPA051895" Enhanced Supported "Plasma membrane,Cytosol" "Intracellular and membrane" Transport NA NA 12000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 8: Immune cells - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 6 Cytosol "Plasma membrane" "CAB017831: , CAB040577: , HPA051895: " "unprognostic (1.14e-2)" "unprognostic (4.25e-2)" "unprognostic (8.84e-2)" "unprognostic (6.61e-2)" "unprognostic (3.86e-1)" "unprognostic (6.80e-2)" "unprognostic (1.31e-3)" "potential prognostic unfavorable (4.34e-4)" "unprognostic (7.13e-2)" "unprognostic (2.90e-1)" "validated prognostic unfavorable (2.77e-5)" "validated prognostic unfavorable (3.43e-4)" "unprognostic (2.84e-2)" "potential prognostic unfavorable (5.74e-6)" "unprognostic (1.84e-2)" "unprognostic (2.83e-3)" "unprognostic (5.06e-3)" "unprognostic (2.25e-1)" "unprognostic (9.27e-3)" "unprognostic (9.26e-2)" "unprognostic (1.59e-1)" "unprognostic (1.47e-1)" "unprognostic (2.48e-3)" "unprognostic (4.46e-2)" "unprognostic (4.71e-2)" "unprognostic (1.01e-1)" "unprognostic (7.03e-2)" "unprognostic (1.26e-1)" "unprognostic (3.87e-1)" "unprognostic (3.19e-1)" "unprognostic (1.59e-1)" FABP6 "I-15P, I-BABP, I-BALB, I-BAP, ILBP, ILBP3, ILLBP" ENSG00000170231 "Fatty acid binding protein 6" P51161 5 160187367-160238735 "Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 84 "intestine: 4264.5" "Cell type enriched" "Detected in many" 21 "Enterocytes: 49086.7" "Cell type enriched" "Detected in many" 5 "ependymal cell: 136.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 62.8" "Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebellum: 6.6" "HPA012601, CAB024713" Enhanced "Intracellular and membrane" Transport NA NA 2800000 "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 44: Non-specific - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 1: Enterocytes - Absorption and Digestion" "CAB024713: , HPA012601: " "unprognostic (9.34e-2)" "potential prognostic unfavorable (6.40e-4)" "unprognostic (1.51e-1)" "unprognostic (2.45e-1)" "unprognostic (1.52e-1)" "unprognostic (1.43e-1)" "potential prognostic unfavorable (5.71e-4)" "unprognostic (3.90e-1)" "unprognostic (3.43e-1)" "unprognostic (1.02e-3)" "unprognostic (1.76e-3)" "unprognostic (1.13e-1)" "potential prognostic unfavorable (7.43e-4)" "validated prognostic unfavorable (7.34e-6)" "validated prognostic unfavorable (3.06e-4)" "unprognostic (8.65e-3)" "unprognostic (1.15e-1)" "potential prognostic unfavorable (9.51e-4)" "unprognostic (3.13e-1)" "unprognostic (2.96e-2)" "unprognostic (3.70e-1)" "unprognostic (2.27e-1)" "unprognostic (9.86e-3)" "unprognostic (8.78e-3)" "unprognostic (4.33e-2)" "unprognostic (8.47e-3)" "unprognostic (4.76e-2)" "potential prognostic unfavorable (4.83e-4)" FABP7 "B-FABP, BLBP" ENSG00000164434 "Fatty acid binding protein 7" O15540 6 122779716-122784074 "FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" Transport "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 232.2;retina: 162.4;tongue: 186.2" "Group enriched" "Detected in some" 6 "Extravillous trophoblasts: 325.7;Müller glia: 895.8" "Cell type enhanced" "Detected in many" "Bergmann glia: 58.7;deep-layer near-projecting: 62.7" "Group enriched" "Detected in many" 10 "Glioblastoma Multiforme (TCGA): 894.0;Kidney Renal Clear Cell Carcinoma (TCGA): 510.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 41.3;Kidney cancer: 40.7;skin cancer: 60.5" "Pituitary gland - Undifferentiated cells (Pituitary gland)" "Region enriched" "Detected in all" 5 "olfactory bulb: 1195.5" "Low region specificity" "Detected in all" "CAB025488, HPA028825, CAB058697" Enhanced Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 27: Cerebellum - Synaptic function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 11: Muller glia cells - Retinal homeostasis" 5 Nucleoplasm "Golgi apparatus, Cytosol" "CAB025488: , CAB058697: , HPA028825: " "unprognostic (1.73e-2)" "potential prognostic favorable (1.58e-4)" "unprognostic (3.92e-1)" "unprognostic (1.52e-1)" "unprognostic (7.27e-2)" "potential prognostic unfavorable (1.91e-4)" "unprognostic (1.94e-2)" "unprognostic (7.43e-3)" "unprognostic (9.44e-2)" "potential prognostic unfavorable (7.16e-4)" "unprognostic (8.74e-2)" "unprognostic (1.13e-1)" "unprognostic (1.07e-1)" "unprognostic (1.71e-1)" "unprognostic (4.34e-3)" "unprognostic (1.27e-1)" "unprognostic (2.55e-2)" "unprognostic (6.28e-2)" FABP9 "PERF, PERF15, T-FABP" ENSG00000205186 "Fatty acid binding protein 9" Q0Z7S8 8 81458253-81461579 "Metabolic proteins, Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 33 "skin 1: 33.5" "Cell type enhanced" "Detected in some" "Adipocytes: 1.8;Ocular epithelial cells: 2.0;Retinal ganglion cells: 3.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Adipocytes (Visceral), Skin - Inner root sheath cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA073619 Enhanced NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 22: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "HPA073619: " FADD "GIG3, MORT1" ENSG00000168040 "Fas associated via death domain" Q13158 11 70203296-70207390 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Immunity, Innate immunity" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 93.4;Esophageal basal cells: 51.3;Esophageal suprabasal cells: 43.2;Extravillous trophoblasts: 42.8;Migrating cytotrophoblasts: 62.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001464, CAB010209" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 70: Non-specific - Protein processing" "Cluster 44: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 60 "Nucleoplasm, Cytosol" "CAB010209: , HPA001464: " "unprognostic (1.06e-3)" "unprognostic (2.74e-1)" "unprognostic (2.74e-1)" "unprognostic (4.01e-2)" "unprognostic (2.83e-2)" "unprognostic (2.46e-2)" "unprognostic (4.51e-2)" "unprognostic (1.78e-1)" "potential prognostic unfavorable (3.86e-4)" "unprognostic (2.24e-2)" "potential prognostic favorable (4.53e-4)" "unprognostic (2.27e-1)" "unprognostic (5.96e-3)" "unprognostic (1.67e-3)" "unprognostic (5.64e-2)" "validated prognostic unfavorable (2.50e-7)" "validated prognostic unfavorable (6.52e-5)" "unprognostic (6.77e-2)" "unprognostic (1.05e-2)" "unprognostic (7.72e-2)" "unprognostic (1.70e-2)" "potential prognostic unfavorable (8.91e-4)" "unprognostic (2.20e-1)" "unprognostic (3.63e-3)" "unprognostic (4.49e-2)" "unprognostic (1.95e-1)" "unprognostic (1.67e-1)" "unprognostic (4.51e-2)" "unprognostic (1.36e-1)" "unprognostic (2.69e-2)" "unprognostic (2.81e-2)" FADS1 "D5D, FADS6, FADSD5, LLCDL1, TU12" ENSG00000149485 "Fatty acid desaturase 1" O60427 11 61799627-61829318 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Transport" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 165.1;Alveolar cells type 2: 199.0;Megakaryocyte progenitors: 123.2;Retinal pigment epithelial cells: 187.6;Thymic myoid cells: 288.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skin - Sebaceous gland cells, Testis - Leydig cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042705 Approved NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 46: Brainstem - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 18: Adrenal cortex cells - Steroidogensis" 2 "HPA042705: " "unprognostic (2.96e-2)" "unprognostic (7.25e-2)" "unprognostic (9.65e-2)" "unprognostic (1.84e-1)" "unprognostic (2.94e-2)" "unprognostic (2.26e-1)" "unprognostic (3.36e-2)" "unprognostic (1.15e-3)" "unprognostic (3.40e-1)" "unprognostic (6.95e-3)" "unprognostic (9.65e-3)" "unprognostic (3.86e-2)" "unprognostic (4.61e-2)" "unprognostic (1.76e-3)" "potential prognostic unfavorable (8.71e-4)" "unprognostic (5.54e-3)" "unprognostic (1.13e-1)" "unprognostic (5.83e-2)" "unprognostic (3.76e-1)" "unprognostic (6.90e-2)" "unprognostic (2.70e-1)" "unprognostic (1.62e-1)" "potential prognostic unfavorable (3.79e-4)" "unprognostic (1.02e-1)" "unprognostic (1.37e-1)" "unprognostic (5.92e-2)" "unprognostic (3.68e-2)" "unprognostic (7.19e-3)" "unprognostic (3.87e-2)" "potential prognostic unfavorable (3.95e-6)" "unprognostic (1.77e-1)" FADS2 "D6D, DES6, FADSD6, LLCDL2, SLL0262, TU13" ENSG00000134824 "Fatty acid desaturase 2" O95864 11 61792980-61867354 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Transport" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 302.5" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 164.1;Astrocytes: 145.0;Megakaryocyte progenitors: 150.3;Retinal ganglion cells: 115.9;Retinal pigment epithelial cells: 183.3" "Cell type enhanced" "Detected in all" "astrocyte: 188.6" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 280.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006741, HPA079284" Approved Approved "Nuclear membrane,Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 46: Brainstem - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 2 "Endoplasmic reticulum" "Nuclear membrane, Plasma membrane" "HPA006741: , HPA079284: " "unprognostic (2.02e-2)" "unprognostic (1.73e-1)" "unprognostic (2.76e-2)" "unprognostic (1.29e-1)" "unprognostic (1.00e-1)" "unprognostic (2.22e-1)" "unprognostic (1.80e-1)" "unprognostic (1.66e-3)" "unprognostic (4.23e-2)" "unprognostic (9.39e-3)" "unprognostic (1.28e-1)" "unprognostic (4.61e-2)" "unprognostic (1.93e-2)" "unprognostic (4.54e-2)" "unprognostic (5.86e-3)" "unprognostic (5.10e-2)" "unprognostic (4.53e-2)" "unprognostic (8.81e-3)" "unprognostic (2.72e-1)" "unprognostic (4.30e-1)" "unprognostic (1.16e-1)" "unprognostic (2.99e-3)" "unprognostic (2.44e-2)" "unprognostic (1.28e-1)" "unprognostic (6.61e-2)" "unprognostic (1.08e-1)" "unprognostic (5.21e-3)" "unprognostic (6.84e-2)" "unprognostic (9.02e-2)" "unprognostic (9.43e-3)" "unprognostic (1.03e-1)" FADS3 "CYB5RP, LLCDL3" ENSG00000221968 "Fatty acid desaturase 3" Q9Y5Q0 11 61873519-61892051 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Transport" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 250.9;Extravillous trophoblasts: 179.6;Schwann cells: 103.5;Vascular smooth muscle cells: 121.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 7.7;naive B-cell: 8.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045224 Approved Approved "Nucleoli fibrillar center" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 23: Choroid plexus - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 103: Non-specific - Basic cellular processes" 9 "Nucleoli fibrillar center" "HPA045224: " "unprognostic (2.60e-2)" "unprognostic (1.01e-1)" "unprognostic (1.41e-1)" "unprognostic (1.21e-2)" "unprognostic (1.84e-2)" "unprognostic (1.40e-2)" "unprognostic (3.94e-3)" "unprognostic (5.92e-2)" "potential prognostic unfavorable (1.05e-4)" "unprognostic (1.49e-1)" "unprognostic (1.43e-3)" "unprognostic (1.24e-3)" "unprognostic (7.14e-2)" "potential prognostic unfavorable (7.60e-4)" "unprognostic (1.14e-2)" "unprognostic (1.23e-1)" "unprognostic (1.19e-1)" "unprognostic (6.47e-2)" "potential prognostic unfavorable (1.21e-4)" "unprognostic (1.89e-1)" "unprognostic (3.62e-1)" "unprognostic (7.61e-2)" "unprognostic (1.75e-3)" "unprognostic (2.87e-1)" "unprognostic (2.04e-1)" "potential prognostic favorable (3.32e-4)" "unprognostic (5.30e-2)" "unprognostic (1.58e-1)" "unprognostic (6.59e-2)" "unprognostic (1.43e-1)" "unprognostic (4.01e-2)" FADS6 ENSG00000172782 "Fatty acid desaturase 6" 17 74877302-74893781 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 12.4;epididymis: 16.9;intestine: 13.1" "Cell type enhanced" "Detected in some" "Adrenal cortex cells: 18.4;Brain excitatory neurons: 7.4;Brain inhibitory neurons: 7.3;Enterocytes: 90.8;Epididymal principal cells: 36.2;Esophageal suprabasal cells: 7.9;Retinal amacrine cells: 8.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016802 Uncertain NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 22: Epididymis - Mixed function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 61: BICR 18 - Protein kinases" "Cluster 1: Enterocytes - Absorption and Digestion" "HPA016802: " "unprognostic (1.25e-1)" "unprognostic (6.63e-3)" "unprognostic (7.35e-3)" "unprognostic (5.87e-2)" "unprognostic (8.23e-2)" "unprognostic (3.02e-1)" "unprognostic (2.78e-1)" "unprognostic (3.61e-2)" "unprognostic (6.59e-2)" "unprognostic (2.60e-1)" "unprognostic (9.83e-3)" "unprognostic (3.18e-1)" "unprognostic (3.17e-2)" "unprognostic (7.50e-2)" "unprognostic (9.79e-2)" "unprognostic (4.05e-2)" FAF1 "CGI-03, hFAF1, HFAF1s, UBXD12, UBXN3A" ENSG00000185104 "Fas associated factor 1" Q9UNN5 1 50437028-50960267 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018253, CAB072814" Approved Enhanced "Nucleoplasm,Acrosome,Equatorial segment,Perinuclear theca" NA NA 22000 "Cluster 16: Non-specific - Cell proliferation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 79: Photoreceptor cells - Phototransduction" 77 Nucleoplasm "Acrosome, Equatorial segment, Perinuclear theca" "CAB072814: , HPA018253: " "unprognostic (4.93e-2)" "unprognostic (2.09e-1)" "unprognostic (1.94e-3)" "unprognostic (4.22e-2)" "unprognostic (1.44e-1)" "unprognostic (2.59e-2)" "unprognostic (8.40e-2)" "unprognostic (1.20e-2)" "unprognostic (2.75e-2)" "unprognostic (8.41e-3)" "unprognostic (1.31e-1)" "unprognostic (1.40e-1)" "unprognostic (2.87e-1)" "validated prognostic unfavorable (1.52e-5)" "validated prognostic unfavorable (6.14e-6)" "unprognostic (6.38e-2)" "unprognostic (1.06e-1)" "unprognostic (1.74e-1)" "unprognostic (3.02e-1)" "unprognostic (1.34e-1)" "unprognostic (4.15e-2)" "unprognostic (4.57e-2)" "unprognostic (3.89e-1)" "unprognostic (9.73e-2)" "unprognostic (1.48e-1)" "unprognostic (1.27e-1)" "unprognostic (2.98e-1)" "unprognostic (1.36e-1)" "unprognostic (2.21e-1)" "unprognostic (3.01e-2)" "unprognostic (8.40e-2)" FAF2 "ETEA, KIAA0887, UBXD8, UBXN3B" ENSG00000113194 "Fas associated factor family member 2" Q96CS3 5 176447628-176510074 "Predicted intracellular proteins, Predicted membrane proteins" "Unfolded protein response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065968, HPA071246, HPA073828" Approved Enhanced "Endoplasmic reticulum,Lipid droplets" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 1: Neurons - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 75 "Lipid droplets" "Endoplasmic reticulum" "HPA065968: , HPA071246: , HPA073828: " "unprognostic (2.56e-1)" "unprognostic (7.43e-3)" "unprognostic (3.87e-1)" "unprognostic (7.68e-2)" "unprognostic (1.19e-2)" "unprognostic (1.58e-1)" "unprognostic (6.60e-2)" "unprognostic (1.42e-2)" "unprognostic (2.45e-2)" "unprognostic (1.58e-3)" "potential prognostic favorable (4.49e-6)" "unprognostic (2.79e-2)" "unprognostic (8.56e-2)" "potential prognostic unfavorable (9.29e-4)" "unprognostic (1.47e-2)" "potential prognostic unfavorable (1.18e-4)" "unprognostic (4.20e-3)" "unprognostic (3.81e-3)" "unprognostic (1.81e-1)" "unprognostic (8.06e-2)" "unprognostic (9.79e-3)" "unprognostic (1.67e-1)" "unprognostic (1.50e-2)" "unprognostic (1.91e-1)" "unprognostic (4.38e-3)" "unprognostic (3.68e-1)" "unprognostic (2.03e-1)" "unprognostic (2.54e-1)" "unprognostic (2.34e-1)" "unprognostic (1.73e-2)" "unprognostic (5.43e-1)" FAH ENSG00000103876 "Fumarylacetoacetate hydrolase" P16930 15 80152490-80186946 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Phenylalanine catabolism, Tyrosine catabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 282.9" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 79.9;Hepatocytes: 339.2;Hofbauer cells: 90.0;Megakaryocytes: 123.6;Platelets: 425.8" "Cell type enhanced" "Detected in many" "astrocyte: 23.9;Bergmann glia: 27.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 33.3" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Pituitary gland - Somatotropes, Spleen - Fibroblasts_2, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041370, HPA044093" Enhanced Approved Nucleoplasm,Cytosol NA NA 54000000 "Cluster 46: Basophils - Proteolysis" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 93: Hepatocytes - Bile production & excretion" 6 Cytosol Nucleoplasm "HPA041370: , HPA044093: " "unprognostic (1.89e-2)" "unprognostic (1.12e-1)" "unprognostic (1.41e-2)" "unprognostic (1.82e-1)" "unprognostic (1.81e-1)" "unprognostic (1.37e-1)" "unprognostic (1.25e-3)" "unprognostic (3.40e-2)" "potential prognostic unfavorable (2.38e-4)" "unprognostic (1.05e-2)" "potential prognostic favorable (4.07e-5)" "unprognostic (1.67e-1)" "unprognostic (3.31e-2)" "unprognostic (1.24e-1)" "unprognostic (4.14e-2)" "unprognostic (2.28e-2)" "unprognostic (6.33e-2)" "unprognostic (3.23e-1)" "unprognostic (3.29e-1)" "unprognostic (1.00e-1)" "unprognostic (4.92e-2)" "unprognostic (8.24e-2)" "unprognostic (8.18e-2)" "unprognostic (2.61e-1)" "unprognostic (1.91e-2)" "unprognostic (1.97e-1)" "unprognostic (3.61e-2)" "unprognostic (1.05e-2)" "unprognostic (1.75e-1)" "unprognostic (2.07e-1)" "unprognostic (1.70e-1)" FAHD1 "C16orf36, DKFZP566J2046" ENSG00000180185 "Fumarylacetoacetate hydrolase domain containing 1" Q6P587 16 1826967-1840207 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Isomerase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 69.0" "Cell type enhanced" "Detected in many" "Early spermatids: 117.4;Enterocytes: 99.2;Esophageal suprabasal cells: 85.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025530, HPA043226, HPA043534" Enhanced Enhanced Nucleoplasm,Mitochondria NA NA 9000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 76: Non-specific - Metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 54: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 2 Mitochondria Nucleoplasm "CAB025530: , HPA043226: , HPA043534: " "unprognostic (9.19e-2)" "unprognostic (1.01e-1)" "unprognostic (1.68e-1)" "unprognostic (4.43e-1)" "unprognostic (7.53e-3)" "unprognostic (9.63e-2)" "unprognostic (6.29e-2)" "unprognostic (5.91e-2)" "unprognostic (4.10e-3)" "unprognostic (2.82e-1)" "potential prognostic favorable (2.30e-10)" "unprognostic (1.80e-2)" "unprognostic (3.07e-3)" "unprognostic (1.14e-1)" "unprognostic (2.61e-1)" "unprognostic (2.00e-1)" "unprognostic (5.29e-2)" "unprognostic (9.10e-2)" "unprognostic (3.22e-2)" "unprognostic (1.91e-1)" "unprognostic (3.44e-2)" "unprognostic (3.58e-1)" "unprognostic (3.65e-1)" "unprognostic (5.76e-2)" "unprognostic (6.08e-3)" "unprognostic (1.04e-1)" "unprognostic (2.10e-2)" "unprognostic (3.30e-1)" "unprognostic (3.00e-1)" "unprognostic (1.68e-1)" "unprognostic (2.50e-2)" FAHD2A CGI-105 ENSG00000115042 "Fumarylacetoacetate hydrolase domain containing 2A" Q96GK7 2 95402708-95416616 "Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 107.6" "Cell type enhanced" "Detected in many" "Early spermatids: 60.3;Enterocytes: 64.9;Lacrimal acinar cells: 76.1;Late spermatids: 52.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042145, HPA044987, CAB045971, CAB045972" Enhanced NA NA 100000 "Cluster 13: Non-specific - Mitochondria" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 53: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 9 "CAB045971: , CAB045972: , HPA042145: , HPA044987: " "unprognostic (4.56e-2)" "unprognostic (2.20e-2)" "unprognostic (6.22e-2)" "potential prognostic favorable (2.93e-4)" "unprognostic (1.81e-1)" "unprognostic (9.24e-2)" "potential prognostic unfavorable (1.21e-4)" "potential prognostic favorable (4.10e-4)" "unprognostic (1.46e-1)" "unprognostic (9.51e-2)" "unprognostic (7.67e-2)" "unprognostic (2.62e-1)" "unprognostic (7.56e-3)" "unprognostic (1.34e-1)" "unprognostic (4.69e-2)" "unprognostic (2.50e-1)" "unprognostic (5.32e-2)" "unprognostic (2.81e-1)" "unprognostic (6.76e-3)" "unprognostic (3.16e-1)" "unprognostic (3.10e-2)" "unprognostic (3.20e-1)" "unprognostic (3.08e-1)" "unprognostic (1.16e-1)" "unprognostic (2.84e-2)" "unprognostic (6.17e-2)" "unprognostic (9.05e-2)" "unprognostic (5.93e-2)" "unprognostic (1.35e-1)" "unprognostic (4.48e-3)" "unprognostic (1.35e-1)" FAHD2B DKFZp434N062 ENSG00000144199 "Fumarylacetoacetate hydrolase domain containing 2B" Q6P2I3 2 97083583-97094882 "Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Early spermatids: 259.1;Epididymal principal cells: 117.6;Late primary spermatocytes: 120.2;Late spermatids: 302.7;Oocytes: 96.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "HPA042145, HPA044987" Approved NA NA "Cluster 1: T-cells - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 6 "HPA042145: , HPA044987: " "potential prognostic unfavorable (7.55e-4)" "unprognostic (6.73e-2)" "unprognostic (1.76e-3)" "potential prognostic favorable (5.37e-4)" "unprognostic (4.11e-2)" "unprognostic (9.16e-2)" "unprognostic (1.05e-3)" "potential prognostic unfavorable (3.69e-5)" "unprognostic (6.85e-3)" "unprognostic (1.21e-1)" "unprognostic (5.29e-2)" "unprognostic (1.48e-1)" "unprognostic (5.65e-2)" "unprognostic (4.92e-3)" "unprognostic (1.82e-1)" "unprognostic (8.01e-2)" "unprognostic (2.98e-1)" "unprognostic (2.27e-1)" "unprognostic (7.01e-3)" "unprognostic (9.21e-2)" "unprognostic (7.45e-2)" "unprognostic (2.54e-2)" "unprognostic (1.80e-1)" "unprognostic (3.43e-1)" "unprognostic (1.03e-1)" "unprognostic (2.55e-1)" "unprognostic (2.18e-1)" "unprognostic (1.35e-1)" "unprognostic (3.80e-2)" "unprognostic (1.05e-3)" "unprognostic (4.27e-2)" FAIM "FAIM1, FLJ10582" ENSG00000158234 "Fas apoptotic inhibitory molecule" Q9NVQ4 3 138608606-138633376 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "retina: 217.5" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 191.0;Fallopian tube ciliated cells: 342.4;Respiratory ciliated cells: 138.7;Rod photoreceptor cells: 182.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA042440, HPA052209" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 32: Basophils - Transcription" "Cluster 42: Retina - Visual perception" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" 3 "Plasma membrane, Cytosol" "HPA042440: , HPA052209: " "unprognostic (1.72e-1)" "unprognostic (4.62e-2)" "unprognostic (7.26e-2)" "unprognostic (2.19e-2)" "unprognostic (2.26e-1)" "unprognostic (1.38e-1)" "unprognostic (1.09e-1)" "unprognostic (1.03e-1)" "unprognostic (1.01e-1)" "unprognostic (6.95e-2)" "potential prognostic favorable (1.54e-4)" "unprognostic (7.36e-2)" "unprognostic (1.92e-2)" "potential prognostic unfavorable (3.51e-5)" "unprognostic (3.58e-3)" "unprognostic (6.22e-2)" "unprognostic (1.61e-2)" "unprognostic (5.39e-2)" "unprognostic (2.14e-2)" "unprognostic (4.67e-2)" "unprognostic (2.74e-1)" "unprognostic (4.28e-2)" "unprognostic (7.66e-2)" "unprognostic (1.03e-1)" "unprognostic (2.53e-1)" "unprognostic (2.22e-2)" "unprognostic (1.63e-1)" "unprognostic (4.40e-2)" "unprognostic (6.34e-2)" "unprognostic (5.64e-2)" "unprognostic (1.03e-1)" FAIM2 "KIAA0950, LFG, LFG2, LIFEGUARD, NMP35, TMBIM2" ENSG00000135472 "Fas apoptotic inhibitory molecule 2" Q9BWQ8 12 49866896-49904217 "Predicted membrane proteins, Transporters" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 309.1;parathyroid gland: 91.9" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 127.6;Bergmann glia: 56.5;Brain excitatory neurons: 104.1;Brain inhibitory neurons: 147.0;Early spermatids: 189.5;Ependymal cells: 108.9;Late primary spermatocytes: 179.9;Late spermatids: 57.9;Oligodendrocyte progenitor cells: 63.4;Oligodendrocytes: 102.3;Other brain neurons: 148.6;Retinal amacrine cells: 94.3;Retinal bipolar cells: 106.1;Retinal horizontal cells: 138.2" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 7 "Glioblastoma Multiforme (TCGA): 74.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 3.0" "Lineage enriched" "Detected in single" 8 "T-cells: 3.0" "Cancer enriched" "Detected in many" 5 "Neuroblastoma: 38.5" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Kidney - Fibroblasts, Lung - Fibroblasts_2, Minor Salivary Gland - Fibroblasts, Pituitary gland - Undifferentiated cells (Pituitary gland), Prostate - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018790, HPA048800" Enhanced Uncertain "Intermediate filaments" NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 98: Neurons - Neurotransmission & signaling" 4 "Intermediate filaments" "HPA018790: , HPA048800: " "unprognostic (1.56e-2)" "unprognostic (7.46e-2)" "unprognostic (2.06e-1)" "potential prognostic favorable (1.59e-4)" "unprognostic (6.09e-2)" "unprognostic (1.95e-1)" "unprognostic (8.50e-3)" "unprognostic (1.80e-2)" "unprognostic (1.26e-3)" "unprognostic (1.18e-1)" "unprognostic (1.90e-1)" "unprognostic (1.05e-3)" "unprognostic (2.95e-2)" "unprognostic (3.25e-2)" "unprognostic (1.77e-2)" "unprognostic (3.94e-2)" "unprognostic (1.83e-1)" "unprognostic (1.05e-1)" "unprognostic (8.59e-3)" "unprognostic (2.34e-1)" "unprognostic (2.77e-1)" "unprognostic (4.11e-2)" FAM102A "bA203J24.7, C9orf132, Eeig1, SYM-3A" ENSG00000167106 "Family with sequence similarity 102 member A" Q5T9C2 9 127940582-127980989 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 202.9;Enterocytes: 241.6;Esophageal apical cells: 282.8;Foveolar cells: 440.3" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 139.2;oligodendrocyte: 164.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Pituitary gland - Lactotropes, Spleen - B-cells (Spleen), Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036030 Approved Cytosol NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 68: Foveolar cells - Mucosal defense" 2 Cytosol "HPA036030: " "unprognostic (2.39e-1)" "unprognostic (2.62e-1)" "unprognostic (5.09e-1)" "unprognostic (2.45e-3)" "unprognostic (4.00e-2)" "unprognostic (1.28e-3)" "unprognostic (3.04e-1)" "unprognostic (3.65e-1)" "unprognostic (3.95e-2)" "potential prognostic favorable (1.15e-4)" "unprognostic (4.20e-2)" "unprognostic (2.56e-1)" "unprognostic (1.16e-1)" "unprognostic (7.58e-2)" "unprognostic (8.89e-2)" "unprognostic (1.84e-1)" "unprognostic (5.79e-2)" "unprognostic (2.90e-1)" "unprognostic (1.64e-2)" "unprognostic (1.66e-2)" "unprognostic (8.10e-2)" "unprognostic (6.57e-2)" "unprognostic (8.06e-2)" "unprognostic (5.02e-2)" "unprognostic (1.75e-1)" "unprognostic (1.58e-1)" "unprognostic (3.15e-2)" "unprognostic (1.68e-1)" "unprognostic (1.59e-1)" "unprognostic (8.66e-2)" "unprognostic (5.66e-2)" FAM102B "DKFZp779B126, SYM-3B" ENSG00000162636 "Family with sequence similarity 102 member B" Q5T8I3 1 108560089-108644900 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "cDC: 159.1;Kupffer cells: 139.4;Macrophages: 176.4;Mast cells: 157.8;Microglia: 190.0;monocytes: 252.0;Neutrophil progenitors: 249.0;Urothelial cells: 147.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Testis - Spermatogonia, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028451 Uncertain Approved Nucleoli,Cytosol NA NA "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 14: Neurons - Synaptic function" "Cluster 7: Liver cancer - Metabolism" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" "Nucleoli, Cytosol" "HPA028451: " "unprognostic (1.85e-2)" "unprognostic (2.26e-1)" "unprognostic (2.59e-2)" "unprognostic (6.67e-2)" "unprognostic (2.19e-3)" "unprognostic (1.90e-1)" "unprognostic (1.34e-1)" "unprognostic (1.43e-2)" "potential prognostic favorable (9.64e-4)" "unprognostic (1.87e-2)" "unprognostic (2.17e-2)" "unprognostic (5.79e-2)" "potential prognostic unfavorable (4.53e-4)" "unprognostic (1.29e-1)" "unprognostic (2.33e-2)" "unprognostic (7.65e-3)" "unprognostic (4.77e-2)" "unprognostic (1.78e-1)" "unprognostic (1.45e-1)" "unprognostic (2.94e-2)" "unprognostic (1.10e-1)" "unprognostic (1.01e-2)" "unprognostic (7.75e-2)" "unprognostic (2.17e-2)" "unprognostic (1.23e-2)" "unprognostic (2.89e-2)" "unprognostic (8.86e-2)" "unprognostic (3.23e-1)" "unprognostic (1.71e-1)" "unprognostic (1.30e-1)" FAM104A FLJ14775 ENSG00000133193 "Family with sequence similarity 104 member A" Q969W3 17 73207353-73236753 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 92.9" "Cell type enhanced" "Detected in all" "Early spermatids: 1446.7;Late primary spermatocytes: 786.3;Late spermatids: 2602.2;Syncytiotrophoblasts: 416.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "HPA021459, HPA079514" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 39: Testis - Nuclear processes" "Cluster 15: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 10 Nucleoplasm Cytosol "HPA021459: , HPA079514: " "unprognostic (2.11e-1)" "unprognostic (6.30e-2)" "unprognostic (1.57e-1)" "unprognostic (1.86e-2)" "unprognostic (7.55e-2)" "unprognostic (2.40e-1)" "unprognostic (7.69e-2)" "unprognostic (1.08e-2)" "unprognostic (1.03e-2)" "unprognostic (2.28e-1)" "unprognostic (3.35e-2)" "unprognostic (9.54e-2)" "unprognostic (1.61e-2)" "potential prognostic unfavorable (1.29e-7)" "unprognostic (6.42e-2)" "unprognostic (1.27e-2)" "unprognostic (1.52e-2)" "unprognostic (2.30e-1)" "unprognostic (2.90e-2)" "unprognostic (4.49e-1)" "unprognostic (4.37e-3)" "unprognostic (4.44e-2)" "unprognostic (1.43e-1)" "potential prognostic unfavorable (9.90e-4)" "unprognostic (6.11e-2)" "unprognostic (2.65e-1)" "unprognostic (4.12e-2)" "unprognostic (2.85e-1)" "unprognostic (1.31e-1)" "unprognostic (1.83e-1)" "unprognostic (6.68e-2)" FAM104B "CXorf44, FLJ20434" ENSG00000182518 "Family with sequence similarity 104 member B" Q5XKR9 X 55143102-55161310 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 131.9;Fallopian tube ciliated cells: 138.8;Late spermatids: 350.5;Respiratory ciliated cells: 129.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" HPA049082 Approved NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" "HPA049082: " "unprognostic (7.22e-3)" "unprognostic (8.26e-3)" "unprognostic (7.05e-2)" "unprognostic (3.19e-2)" "unprognostic (2.16e-3)" "unprognostic (2.74e-2)" "unprognostic (3.63e-1)" "unprognostic (6.56e-2)" "unprognostic (1.29e-1)" "unprognostic (1.38e-3)" "unprognostic (1.79e-1)" "unprognostic (1.92e-1)" "unprognostic (2.31e-1)" "potential prognostic unfavorable (4.27e-5)" "unprognostic (1.10e-3)" "unprognostic (5.80e-2)" "unprognostic (1.73e-1)" "unprognostic (4.18e-3)" "potential prognostic favorable (7.51e-4)" "unprognostic (1.87e-3)" "unprognostic (1.84e-1)" "unprognostic (3.25e-2)" "unprognostic (7.95e-2)" "unprognostic (7.04e-3)" "unprognostic (5.44e-2)" "unprognostic (2.13e-1)" "unprognostic (4.83e-2)" "unprognostic (5.29e-2)" "unprognostic (1.21e-1)" "unprognostic (1.53e-2)" "unprognostic (1.16e-1)" FAM107A "DRR1, TU3A" ENSG00000168309 "Family with sequence similarity 107 member A" O95990 3 58564117-58627610 "Predicted intracellular proteins" "Cell cycle, Growth regulation, Stress response" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 1181.3;choroid plexus: 331.5" "Cell type enhanced" "Detected in many" "Astrocytes: 135.9;Bergmann glia: 209.0;Cone photoreceptor cells: 204.9;Endometrial luminal cells: 104.9;Fallopian secretory cells: 219.9;Lacrimal acinar cells: 218.3;Medullary thymic epithelial cells: 192.0;Pituitary stem cells: 238.9;Retinal pigment epithelial cells: 153.5;Rod photoreceptor cells: 194.8;Salivary acinar cells: 262.9;Salivary myoepithelial cells: 96.6;Vascular endothelial cells: 186.2" "Group enriched" "Detected in many" 4 "astrocyte: 119.9;Bergmann glia: 228.4;endothelial cell: 91.3" "Cancer enriched" "Detected in all" 7 "Glioblastoma Multiforme (TCGA): 303.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "ovarian cancer: 12.5;Uterine cancer: 14.5" "Skin - Macrophages, Testis - Endothelial cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" HPA055888 Enhanced Supported "Nuclear speckles" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 8 "Nuclear speckles" "HPA055888: " "unprognostic (3.11e-2)" "unprognostic (1.42e-1)" "unprognostic (2.00e-2)" "unprognostic (4.30e-2)" "unprognostic (2.16e-1)" "unprognostic (2.17e-1)" "unprognostic (2.72e-1)" "potential prognostic unfavorable (9.78e-4)" "unprognostic (5.27e-3)" "unprognostic (4.08e-2)" "potential prognostic favorable (3.33e-8)" "unprognostic (3.56e-3)" "unprognostic (1.62e-1)" "unprognostic (1.46e-3)" "potential prognostic favorable (2.56e-4)" "unprognostic (5.12e-2)" "unprognostic (3.90e-2)" "unprognostic (9.70e-3)" "unprognostic (2.31e-1)" "unprognostic (9.33e-2)" "unprognostic (5.69e-2)" "unprognostic (3.06e-3)" "unprognostic (3.81e-2)" "unprognostic (2.42e-2)" "unprognostic (2.95e-1)" "unprognostic (6.97e-2)" "unprognostic (7.17e-3)" "unprognostic (3.25e-2)" "unprognostic (3.03e-1)" "unprognostic (1.34e-1)" "unprognostic (8.27e-2)" FAM107B "C10orf45, FLJ45505, HITS, MGC11034" ENSG00000065809 "Family with sequence similarity 107 member B" Q9H098 10 14518557-14774897 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Mast cells: 922.0;monocytes: 947.9;Neutrophil progenitors: 1631.4;Neutrophils: 2431.2;Pancreatic acinar cells: 1019.7;Urothelial cells: 1282.3" "Cell type enhanced" "Detected in all" "oligodendrocyte: 865.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "granulocytes: 64.0;NK-cells: 54.0;T-cells: 106.6" "Cancer enhanced" "Detected in all" "lymphoma: 264.4" "Heart muscle - Fibroblasts, Lung - Alveolar cells type 1, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "HPA039661, HPA058814, HPA073195" Approved Supported "Nucleoplasm,Golgi apparatus" NA NA 71000 "Cluster 11: T-cells - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 1 Nucleoplasm "Golgi apparatus" "HPA039661: , HPA058814: , HPA073195: " "unprognostic (2.69e-2)" "unprognostic (1.55e-1)" "unprognostic (1.07e-1)" "unprognostic (3.16e-1)" "unprognostic (8.15e-3)" "unprognostic (1.01e-2)" "unprognostic (5.45e-1)" "unprognostic (1.61e-3)" "unprognostic (1.25e-2)" "unprognostic (2.07e-3)" "potential prognostic favorable (8.38e-5)" "unprognostic (1.15e-2)" "unprognostic (1.79e-1)" "unprognostic (2.51e-1)" "unprognostic (6.88e-2)" "unprognostic (1.61e-1)" "unprognostic (1.42e-1)" "unprognostic (6.17e-3)" "unprognostic (1.02e-1)" "unprognostic (1.58e-1)" "unprognostic (1.58e-1)" "unprognostic (2.39e-2)" "unprognostic (2.43e-1)" "unprognostic (2.69e-1)" "unprognostic (3.44e-1)" "unprognostic (3.53e-1)" "unprognostic (3.11e-1)" "unprognostic (2.16e-1)" "unprognostic (2.36e-1)" "unprognostic (2.06e-2)" "unprognostic (1.96e-1)" FAM110A "bA371L19.3, C20orf55" ENSG00000125898 "Family with sequence similarity 110 member A" Q9BQ89 20 833715-857463 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 68.7" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 96.3;Esophageal basal cells: 59.5;Esophageal suprabasal cells: 75.5;Extravillous trophoblasts: 218.7;Megakaryocytes: 86.5;Migrating cytotrophoblasts: 58.3;Platelets: 260.0" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 12.3;leukocyte: 23.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "basophil: 546.1;eosinophil: 163.7;intermediate monocyte: 160.5;non-classical monocyte: 249.3" "Group enriched" "Detected in all" 9 "granulocytes: 546.1;monocytes: 249.3" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells, Skin - Keratinocyte (granular), Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB034110, HPA069240" Uncertain Uncertain Nucleoplasm,Vesicles,Cytosol Yes Yes "Cluster 25: Non-specific - Unknown function" "Cluster 58: Skin - Keratinization" "Cluster 49: Hindbrain - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 44 "Nucleoplasm, Vesicles" Cytosol "CAB034110: , HPA069240: " "unprognostic (9.56e-2)" "unprognostic (6.43e-3)" "unprognostic (1.82e-2)" "unprognostic (2.98e-1)" "unprognostic (5.92e-2)" "unprognostic (1.61e-1)" "unprognostic (2.14e-1)" "unprognostic (6.01e-2)" "unprognostic (1.15e-1)" "unprognostic (6.44e-2)" "unprognostic (1.61e-1)" "unprognostic (6.44e-2)" "unprognostic (2.85e-1)" "potential prognostic unfavorable (5.00e-4)" "unprognostic (2.67e-2)" "unprognostic (1.88e-1)" "unprognostic (2.56e-2)" "unprognostic (2.41e-3)" "unprognostic (6.73e-3)" "unprognostic (3.09e-2)" "unprognostic (2.46e-1)" "unprognostic (3.01e-2)" "unprognostic (6.35e-2)" "unprognostic (1.54e-1)" "unprognostic (7.13e-2)" "unprognostic (1.14e-2)" "unprognostic (1.08e-1)" "unprognostic (1.02e-2)" "unprognostic (2.39e-2)" "unprognostic (7.05e-2)" "unprognostic (1.12e-1)" FAM110B "C8orf72, MGC39325" ENSG00000169122 "Family with sequence similarity 110 member B" Q8TC76 8 57994523-58204279 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 21.1" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 316.3;Epicardial cells: 218.3;Epididymal basal cells: 243.3;Myosatellite cells: 237.5;Oligodendrocyte progenitor cells: 418.8;Renal collecting duct intercalated cells: 231.8;Renal connecting tubule cells: 373.9;Sertoli cells: 393.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 27.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "eosinophil: 14.0;intermediate monocyte: 3.7;non-classical monocyte: 7.1" "Group enriched" "Detected in many" 11 "granulocytes: 14.0;monocytes: 7.1" "Cancer enhanced" "Detected in many" "Rhabdoid: 12.7" "Adipose subcutaneous - Adipose progenitor cells, Prostate - Fibroblasts, Spleen - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008318, HPA011781" Uncertain Supported Mitochondria,Cytosol NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 1: Neurons - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 109: Neurons - Neuronal signaling" 8 "Mitochondria, Cytosol" "HPA008318: , HPA011781: " "unprognostic (1.03e-1)" "unprognostic (5.95e-2)" "unprognostic (9.25e-2)" "unprognostic (1.64e-1)" "unprognostic (6.48e-2)" "potential prognostic favorable (9.60e-5)" "unprognostic (1.38e-1)" "unprognostic (2.63e-2)" "unprognostic (4.66e-3)" "unprognostic (3.71e-3)" "potential prognostic favorable (1.18e-4)" "unprognostic (5.38e-2)" "unprognostic (1.51e-2)" "unprognostic (1.34e-1)" "unprognostic (1.66e-1)" "unprognostic (3.66e-1)" "unprognostic (6.22e-2)" "unprognostic (1.82e-1)" "unprognostic (4.10e-1)" "potential prognostic favorable (4.00e-4)" "unprognostic (2.02e-1)" "unprognostic (3.32e-3)" "unprognostic (8.11e-2)" "unprognostic (1.23e-1)" "unprognostic (3.12e-3)" "unprognostic (1.17e-1)" "unprognostic (1.20e-1)" "unprognostic (1.75e-1)" FAM110C ENSG00000184731 "Family with sequence similarity 110 member C" Q1W6H9 2 38814-46870 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 30.3" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 139.5;Endometrial luminal cells: 250.3;Epididymal basal cells: 327.0;Esophageal apical cells: 261.8;Esophageal suprabasal cells: 111.0;Ocular epithelial cells: 209.6;Urothelial cells: 131.5" "Cell type enhanced" "Detected in many" "eccentric medium spiny neuron: 16.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 18.1" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Pituitary gland - Corticotropes" "Region enriched" "Detected in single" 6 "olfactory bulb: 1.9" "Low region specificity" "Detected in all" "HPA036144, HPA036145" Uncertain NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 4 "HPA036144: , HPA036145: " "unprognostic (3.21e-1)" "unprognostic (1.07e-1)" "unprognostic (1.47e-1)" "unprognostic (2.26e-1)" "unprognostic (2.60e-1)" "unprognostic (2.54e-1)" "validated prognostic unfavorable (2.18e-4)" "validated prognostic unfavorable (4.46e-4)" "unprognostic (1.12e-2)" "unprognostic (2.75e-1)" "potential prognostic favorable (5.66e-8)" "unprognostic (1.78e-3)" "unprognostic (3.26e-1)" "unprognostic (3.50e-1)" "potential prognostic favorable (2.92e-4)" "unprognostic (9.51e-3)" "unprognostic (3.39e-2)" "unprognostic (3.74e-2)" "unprognostic (4.96e-2)" "unprognostic (8.15e-2)" "unprognostic (3.48e-1)" "unprognostic (2.13e-1)" "unprognostic (4.47e-1)" "unprognostic (7.37e-2)" "unprognostic (1.54e-3)" "unprognostic (1.29e-1)" "unprognostic (2.12e-1)" "unprognostic (5.03e-3)" "unprognostic (2.58e-2)" "unprognostic (2.42e-1)" FAM110D "FLJ14050, GRRP1" ENSG00000197245 "Family with sequence similarity 110 member D" Q8TAY7 1 26159079-26163962 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 8 "Vascular endothelial cells: 107.1" "Cell type enriched" "Detected in some" 13 "endothelial cell: 32.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.2" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA013664 Approved NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 47: Endothelial cells - Vasculature" "Cluster 54: Non-specific - Transcription" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 6 "HPA013664: " "unprognostic (5.56e-2)" "unprognostic (1.35e-1)" "unprognostic (5.62e-3)" "unprognostic (5.79e-2)" "unprognostic (1.51e-1)" "unprognostic (2.21e-1)" "unprognostic (2.12e-1)" "validated prognostic favorable (2.96e-5)" "validated prognostic favorable (9.00e-4)" "unprognostic (7.65e-2)" "unprognostic (6.28e-3)" "unprognostic (1.97e-1)" "unprognostic (2.20e-2)" "unprognostic (1.82e-1)" "unprognostic (7.17e-2)" "unprognostic (1.25e-1)" "unprognostic (1.70e-1)" "unprognostic (1.15e-1)" "unprognostic (6.50e-2)" FAM111A "FLJ22794, KIAA1895" ENSG00000166801 "FAM111 trypsin like peptidase A" Q96PZ2 11 59142748-59155039 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, Host-virus interaction" "DNA-binding, Hydrolase, Protease" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Monocyte progenitors: 236.3;Neutrophil progenitors: 120.7" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 73.2;endothelial cell: 75.5;leukocyte: 63.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039529, HPA040176" Approved Approved "Nucleoplasm,Nucleoli fibrillar center" NA Yes "Cluster 33: Non-specific - ATP binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 24: Non-specific - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 41 "Nucleoplasm, Nucleoli fibrillar center" "HPA039529: , HPA040176: " "unprognostic (1.64e-2)" "unprognostic (1.69e-2)" "unprognostic (1.07e-1)" "unprognostic (1.29e-1)" "unprognostic (1.59e-1)" "unprognostic (1.43e-1)" "unprognostic (2.63e-1)" "unprognostic (3.87e-2)" "unprognostic (1.11e-1)" "unprognostic (2.61e-2)" "unprognostic (3.85e-3)" "unprognostic (1.09e-1)" "unprognostic (5.11e-3)" "unprognostic (4.19e-3)" "potential prognostic favorable (4.15e-4)" "unprognostic (2.27e-2)" "unprognostic (7.57e-2)" "unprognostic (2.17e-1)" "unprognostic (4.43e-1)" "unprognostic (5.39e-2)" "unprognostic (1.16e-1)" "unprognostic (2.06e-2)" "unprognostic (4.31e-2)" "unprognostic (1.31e-1)" "unprognostic (1.58e-2)" "unprognostic (1.78e-1)" "unprognostic (2.09e-1)" "unprognostic (1.92e-2)" "unprognostic (5.17e-2)" "unprognostic (4.40e-3)" "unprognostic (3.68e-1)" FAM111B CANP ENSG00000189057 "FAM111 trypsin like peptidase B" Q6SJ93 11 59107185-59127412 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Hydrolase, Protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 16.7" "Cell type enriched" "Detected in many" 11 "Respiratory deuterosomal cells: 433.3" "Cell type enhanced" "Detected in some" "leukocyte: 1.3;oligodendrocyte precursor cell: 1.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 3.3;naive B-cell: 2.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in many" HPA038637 Uncertain Approved Nucleoplasm,Cytosol No Yes "Cluster 14: Non-specific - Unknown function" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 9: Non-specific - Receptor signaling" "Cluster 24: Non-specific - Unknown function" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 6 Nucleoplasm Cytosol "HPA038637: " "unprognostic (1.67e-1)" "unprognostic (1.55e-1)" "unprognostic (2.40e-2)" "unprognostic (8.60e-2)" "unprognostic (1.29e-1)" "unprognostic (6.36e-2)" "unprognostic (4.04e-1)" "unprognostic (4.14e-2)" "unprognostic (2.30e-2)" "potential prognostic unfavorable (1.09e-5)" "unprognostic (5.94e-2)" "unprognostic (5.68e-2)" "potential prognostic unfavorable (7.34e-6)" "potential prognostic unfavorable (1.80e-4)" "unprognostic (5.96e-3)" "potential prognostic unfavorable (1.29e-6)" "unprognostic (1.20e-3)" "unprognostic (2.43e-1)" "unprognostic (6.96e-2)" "unprognostic (4.11e-2)" "unprognostic (4.56e-2)" "potential prognostic unfavorable (6.45e-5)" "unprognostic (1.00e-1)" "unprognostic (6.79e-3)" "unprognostic (1.48e-3)" "unprognostic (2.42e-1)" "unprognostic (1.42e-1)" "unprognostic (4.46e-2)" "unprognostic (1.43e-1)" "potential prognostic favorable (3.69e-4)" "unprognostic (2.42e-2)" FAM114A1 Noxp20 ENSG00000197712 "Family with sequence similarity 114 member A1" Q8IWE2 4 38867677-38945739 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 264.5;Lacrimal acinar cells: 345.1;Salivary acinar cells: 221.7;Salivary ionocytes: 270.7" "Cell type enhanced" "Detected in many" "fibroblast: 134.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 3.2;intermediate monocyte: 3.6;myeloid DC: 2.6;neutrophil: 2.4;non-classical monocyte: 1.4" "Group enriched" "Detected in many" 7 "dendritic cells: 2.6;granulocytes: 2.4;monocytes: 3.6" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Liver - Hepatocytes, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067948, HPA069104, HPA069701" Uncertain Enhanced "Nucleoplasm,Golgi apparatus,Cytosol" No No 13000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 75: Ovary - Mixed function" "Cluster 8: Immune cells - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 10 "Golgi apparatus, Cytosol" Nucleoplasm "HPA067948: , HPA069104: , HPA069701: " "unprognostic (2.14e-2)" "unprognostic (9.94e-3)" "unprognostic (3.91e-1)" "unprognostic (5.95e-3)" "unprognostic (5.46e-2)" "unprognostic (1.66e-2)" "unprognostic (4.04e-2)" "potential prognostic unfavorable (1.69e-4)" "unprognostic (9.03e-2)" "unprognostic (1.31e-2)" "potential prognostic favorable (4.11e-4)" "unprognostic (2.79e-1)" "unprognostic (5.52e-3)" "unprognostic (1.68e-1)" "unprognostic (9.44e-2)" "unprognostic (3.27e-2)" "potential prognostic unfavorable (5.67e-4)" "unprognostic (5.93e-2)" "unprognostic (1.43e-1)" "unprognostic (3.00e-1)" "unprognostic (3.80e-2)" "unprognostic (5.56e-2)" "unprognostic (1.56e-1)" "unprognostic (2.44e-1)" "unprognostic (5.77e-2)" "unprognostic (2.31e-1)" "unprognostic (5.43e-2)" "unprognostic (1.28e-1)" "unprognostic (1.78e-1)" "unprognostic (1.24e-2)" "unprognostic (1.23e-1)" FAM114A2 "133K02, C5orf3" ENSG00000055147 "Family with sequence similarity 114 member A2" Q9NRY5 5 153990148-154038936 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 106.1;Late primary spermatocytes: 99.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035869, HPA035870" Approved Approved Vesicles NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 3: Early primary spermatocytes - Early meiosis" 12 Vesicles "HPA035869: , HPA035870: " "unprognostic (1.11e-1)" "unprognostic (1.16e-1)" "unprognostic (3.09e-1)" "unprognostic (4.46e-3)" "unprognostic (1.67e-1)" "unprognostic (1.46e-1)" "unprognostic (2.96e-1)" "unprognostic (6.35e-2)" "unprognostic (1.66e-1)" "unprognostic (4.94e-3)" "potential prognostic favorable (2.07e-6)" "unprognostic (7.70e-3)" "unprognostic (1.58e-1)" "unprognostic (1.21e-2)" "unprognostic (1.43e-1)" "unprognostic (4.65e-2)" "unprognostic (5.93e-2)" "unprognostic (3.31e-3)" "unprognostic (1.50e-1)" "unprognostic (1.71e-1)" "unprognostic (3.33e-2)" "unprognostic (3.60e-1)" "potential prognostic unfavorable (6.91e-4)" "unprognostic (3.00e-1)" "unprognostic (9.49e-2)" "unprognostic (1.35e-1)" "unprognostic (2.81e-1)" "unprognostic (4.21e-3)" "unprognostic (1.73e-1)" "unprognostic (1.18e-2)" "unprognostic (2.34e-1)" FAM117A ENSG00000121104 "Family with sequence similarity 117 member A" Q9C073 17 49710332-49789180 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 72.2" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 193.6;Erythrocyte progenitors: 168.3;Hematopoietic stem cells: 207.2;Megakaryocyte-Erythroid progenitors: 255.4;NK-cells: 102.8;Thymocytes: 169.4" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 141.1;leukocyte: 120.9" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "choroid plexus: 76.6" "Immune cell enhanced" "Detected in many" "basophil: 50.5" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 62.9" "Kidney - Fibroblasts, Stomach - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022531 Approved Approved Nucleoplasm NA NA "Cluster 32: Basophils - Transcription" "Cluster 15: Bone marrow - Innate immune response" "Cluster 23: Choroid plexus - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 20: Non-specific - Transcription regulation" 12 Nucleoplasm "HPA022531: " "unprognostic (7.16e-2)" "potential prognostic favorable (5.43e-4)" "unprognostic (8.74e-2)" "unprognostic (1.65e-1)" "unprognostic (4.18e-3)" "unprognostic (3.24e-1)" "unprognostic (2.54e-1)" "unprognostic (3.73e-2)" "unprognostic (1.55e-2)" "unprognostic (1.06e-1)" "potential prognostic favorable (3.72e-5)" "unprognostic (1.08e-2)" "unprognostic (1.92e-1)" "unprognostic (1.31e-1)" "unprognostic (7.83e-2)" "potential prognostic favorable (7.36e-6)" "unprognostic (1.58e-2)" "unprognostic (2.43e-1)" "unprognostic (8.32e-2)" "unprognostic (9.32e-2)" "unprognostic (6.48e-2)" "potential prognostic favorable (2.59e-4)" "unprognostic (1.48e-1)" "unprognostic (4.47e-2)" "unprognostic (2.24e-1)" "unprognostic (6.51e-2)" "unprognostic (4.16e-1)" "unprognostic (5.84e-2)" "unprognostic (1.31e-1)" "unprognostic (7.24e-2)" "unprognostic (2.94e-1)" FAM117B "ALS2CR13, FLJ38771" ENSG00000138439 "Family with sequence similarity 117 member B" Q6P1L5 2 202634969-202769757 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "B-cells: 200.1;Prostatic glandular cells: 202.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skin - Keratinocyte (other), Spleen - B-cells (Spleen), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003229, HPA028746" Uncertain Approved Nucleoplasm,Centrosome Yes No "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 43 Nucleoplasm Centrosome "HPA003229: , HPA028746: " "unprognostic (2.05e-1)" "unprognostic (1.16e-1)" "unprognostic (1.24e-1)" "unprognostic (8.51e-2)" "unprognostic (2.34e-1)" "unprognostic (2.31e-2)" "unprognostic (1.21e-1)" "unprognostic (1.02e-3)" "unprognostic (2.59e-2)" "unprognostic (1.84e-1)" "potential prognostic favorable (6.88e-5)" "unprognostic (1.78e-2)" "unprognostic (1.35e-1)" "unprognostic (1.70e-2)" "unprognostic (2.62e-2)" "unprognostic (2.61e-1)" "unprognostic (7.11e-2)" "unprognostic (3.40e-2)" "potential prognostic favorable (5.30e-5)" "unprognostic (7.73e-2)" "unprognostic (2.39e-1)" "unprognostic (2.75e-2)" "unprognostic (1.17e-2)" "unprognostic (4.07e-1)" "unprognostic (3.75e-3)" "unprognostic (1.96e-1)" "unprognostic (7.97e-2)" "unprognostic (2.15e-1)" "unprognostic (3.81e-1)" "unprognostic (1.17e-1)" "unprognostic (2.73e-1)" FAM118A "bK268H5.C22.4, C22orf8, FLJ20635" ENSG00000100376 "Family with sequence similarity 118 member A" Q9NWS6 22 45308968-45341955 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 137.7;Early spermatids: 166.9;Ependymal cells: 165.4;Microglia: 170.6;Syncytiotrophoblasts: 147.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003902 Uncertain Uncertain "Intermediate filaments,Cytosol" NA NA "Cluster 18: Non-specific - Translation" "Cluster 49: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 9: T-cells - Adaptive immunity: Regulation" 12 "Intermediate filaments" Cytosol "HPA003902: " "unprognostic (7.48e-3)" "unprognostic (3.81e-2)" "unprognostic (1.62e-2)" "unprognostic (7.24e-2)" "unprognostic (1.21e-1)" "unprognostic (1.18e-1)" "unprognostic (2.74e-1)" "unprognostic (1.82e-1)" "unprognostic (2.49e-2)" "unprognostic (1.65e-1)" "unprognostic (1.47e-2)" "unprognostic (1.69e-1)" "unprognostic (1.83e-1)" "unprognostic (6.47e-3)" "unprognostic (8.80e-2)" "unprognostic (1.38e-1)" "unprognostic (1.80e-1)" "unprognostic (1.20e-2)" "unprognostic (3.29e-3)" "unprognostic (2.22e-2)" "unprognostic (2.61e-1)" "unprognostic (4.36e-3)" "unprognostic (1.26e-1)" "unprognostic (1.35e-2)" "unprognostic (3.18e-2)" "unprognostic (4.14e-2)" "unprognostic (4.72e-3)" "unprognostic (2.62e-1)" "unprognostic (4.56e-2)" "unprognostic (2.26e-1)" "potential prognostic favorable (8.05e-4)" FAM118B FLJ21103 ENSG00000197798 "Family with sequence similarity 118 member B" Q9BPY3 11 126211724-126262984 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 72.4;Pituicytes/FSCs: 82.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041644, HPA042100" Approved NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 15 "HPA041644: , HPA042100: " "unprognostic (3.26e-2)" "unprognostic (3.02e-3)" "unprognostic (3.51e-1)" "unprognostic (8.90e-2)" "unprognostic (1.59e-2)" "unprognostic (1.78e-2)" "unprognostic (8.37e-2)" "unprognostic (1.42e-1)" "unprognostic (7.34e-2)" "unprognostic (1.56e-3)" "potential prognostic favorable (7.39e-4)" "unprognostic (7.76e-2)" "unprognostic (2.28e-1)" "potential prognostic unfavorable (1.58e-7)" "unprognostic (6.47e-3)" "unprognostic (7.93e-2)" "unprognostic (1.01e-1)" "unprognostic (2.64e-1)" "unprognostic (1.03e-1)" "unprognostic (1.48e-1)" "unprognostic (5.24e-2)" "unprognostic (8.35e-2)" "unprognostic (4.23e-2)" "unprognostic (2.85e-1)" "unprognostic (1.38e-2)" "unprognostic (1.19e-1)" "unprognostic (1.99e-3)" "unprognostic (6.34e-2)" "unprognostic (3.48e-1)" "unprognostic (2.21e-1)" "unprognostic (1.82e-2)" FAM120A "C9orf10, KIAA0183, OSSA" ENSG00000048828 "Family with sequence similarity 120A" Q9NZB2 9 93451685-93566112 "Plasma proteins, Predicted intracellular proteins" RNA-binding "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019734, HPA055800" Approved Enhanced Cytosol NA NA 4900 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 76: Non-specific - Metabolism" "Cluster 8: Immune cells - Immune response" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 65 Cytosol "HPA019734: , HPA055800: " "unprognostic (1.47e-2)" "unprognostic (1.27e-1)" "unprognostic (9.78e-2)" "unprognostic (7.22e-3)" "unprognostic (3.06e-1)" "unprognostic (9.40e-2)" "unprognostic (3.22e-1)" "unprognostic (6.37e-3)" "unprognostic (5.46e-2)" "unprognostic (4.79e-2)" "potential prognostic favorable (1.66e-7)" "unprognostic (2.19e-2)" "unprognostic (8.83e-2)" "unprognostic (1.08e-1)" "unprognostic (7.04e-2)" "unprognostic (9.38e-2)" "unprognostic (2.66e-3)" "unprognostic (9.59e-2)" "unprognostic (3.21e-2)" "unprognostic (2.90e-2)" "unprognostic (6.48e-2)" "unprognostic (1.74e-2)" "unprognostic (1.07e-2)" "unprognostic (2.47e-2)" "unprognostic (3.63e-2)" "unprognostic (2.86e-2)" "unprognostic (2.80e-1)" "unprognostic (6.33e-2)" "unprognostic (1.15e-1)" "unprognostic (1.44e-1)" "unprognostic (5.19e-2)" FAM120AOS C9orf10OS ENSG00000188938 "Family with sequence similarity 120A opposite strand" Q5T036 9 93431441-93453581 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 261.4;Migrating cytotrophoblasts: 217.2;Syncytiotrophoblasts: 425.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" HPA021475 Approved NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 33: Thyroid gland - Tissue development" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." 1 "HPA021475: " "unprognostic (4.89e-3)" "unprognostic (2.22e-1)" "unprognostic (4.60e-2)" "unprognostic (4.18e-2)" "unprognostic (7.28e-3)" "unprognostic (1.02e-2)" "unprognostic (1.21e-3)" "unprognostic (8.65e-2)" "unprognostic (3.41e-1)" "unprognostic (2.29e-1)" "potential prognostic favorable (3.80e-6)" "unprognostic (5.62e-3)" "unprognostic (1.50e-2)" "potential prognostic unfavorable (5.45e-5)" "unprognostic (6.61e-3)" "unprognostic (1.05e-1)" "unprognostic (3.28e-1)" "unprognostic (1.31e-1)" "unprognostic (1.37e-1)" "unprognostic (3.07e-1)" "unprognostic (8.09e-2)" "unprognostic (2.12e-2)" "unprognostic (2.94e-2)" "unprognostic (3.88e-2)" "unprognostic (2.35e-1)" "unprognostic (1.14e-1)" "unprognostic (3.41e-2)" "unprognostic (5.84e-2)" "unprognostic (4.99e-1)" "unprognostic (2.01e-2)" "unprognostic (4.46e-2)" FAM120B "CCPG, KIAA1838, PGCC1, SAN1" ENSG00000112584 "Family with sequence similarity 120B" Q96EK7 6 170290703-170407067 "Predicted intracellular proteins" "Differentiation, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Late spermatids: 2298.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037518, HPA037519" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 64: Non-specific - Transcription" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 10 Nucleoplasm Cytosol "HPA037518: , HPA037519: " "unprognostic (5.22e-2)" "unprognostic (2.76e-3)" "unprognostic (4.01e-2)" "unprognostic (4.18e-3)" "unprognostic (3.63e-2)" "unprognostic (1.58e-2)" "unprognostic (4.88e-2)" "unprognostic (8.67e-3)" "unprognostic (5.65e-2)" "unprognostic (2.43e-1)" "potential prognostic favorable (2.74e-4)" "unprognostic (3.54e-2)" "unprognostic (1.31e-1)" "unprognostic (9.32e-3)" "unprognostic (2.24e-1)" "unprognostic (5.09e-2)" "unprognostic (7.82e-2)" "unprognostic (5.95e-3)" "unprognostic (1.52e-2)" "unprognostic (6.36e-3)" "unprognostic (3.29e-1)" "unprognostic (1.05e-1)" "unprognostic (1.41e-2)" "unprognostic (7.66e-2)" "unprognostic (1.15e-3)" "unprognostic (6.95e-2)" "unprognostic (5.33e-2)" "unprognostic (3.49e-1)" "unprognostic (5.51e-2)" "unprognostic (2.83e-1)" "unprognostic (5.07e-2)" FAM120C "CXorf17, FLJ20506, ORF34" ENSG00000184083 "Family with sequence similarity 120C" Q9NX05 X 54068324-54183281 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047677, HPA054250" Uncertain Approved "Nuclear membrane,Endoplasmic reticulum" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 65: Brain - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 7: Non-specific - Transcription" 6 "Nuclear membrane" "Endoplasmic reticulum" "HPA047677: , HPA054250: " "unprognostic (7.22e-2)" "unprognostic (2.26e-2)" "unprognostic (2.38e-1)" "unprognostic (5.67e-2)" "unprognostic (1.04e-2)" "unprognostic (3.22e-2)" "unprognostic (3.98e-2)" "unprognostic (1.61e-3)" "unprognostic (2.38e-2)" "unprognostic (7.61e-3)" "unprognostic (2.08e-1)" "unprognostic (1.69e-1)" "unprognostic (3.60e-2)" "potential prognostic unfavorable (1.40e-4)" "unprognostic (1.11e-2)" "unprognostic (6.28e-2)" "unprognostic (3.20e-1)" "unprognostic (7.29e-3)" "unprognostic (6.87e-3)" "unprognostic (1.49e-1)" "unprognostic (1.61e-2)" "unprognostic (5.75e-3)" "unprognostic (1.20e-1)" "unprognostic (2.98e-1)" "unprognostic (1.43e-1)" "unprognostic (4.25e-3)" "unprognostic (2.36e-1)" "unprognostic (1.70e-3)" "unprognostic (5.21e-2)" "unprognostic (7.13e-2)" "unprognostic (1.76e-1)" FAM124A FLJ30707 ENSG00000150510 "Family with sequence similarity 124 member A" Q86V42 13 51222334-51284239 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.1;choroid plexus: 21.4;retina: 23.8" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 170.9;Cone photoreceptor cells: 93.2;Conjunctival goblet cells: 46.6;Ependymal cells: 100.9;Epicardial cells: 61.4;Medullary thymic epithelial cells: 50.4;Oligodendrocytes: 277.5;Pituitary stem cells: 56.8;Rod photoreceptor cells: 118.1" "Cell type enhanced" "Detected in all" "oligodendrocyte: 396.6" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 11.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 6.6" "Breast - Endothelial cells, Kidney - Proximal tubular cells, Prostate - Smooth muscle cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048182 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 11: White matter - Signal transduction" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 80: Oligodendrocytes - Myelination" 22 Nucleoplasm Cytosol "HPA048182: " "unprognostic (1.36e-2)" "unprognostic (1.04e-2)" "unprognostic (1.55e-2)" "unprognostic (2.55e-1)" "unprognostic (2.48e-1)" "unprognostic (2.34e-1)" "unprognostic (6.99e-2)" "unprognostic (2.72e-2)" "unprognostic (5.40e-2)" "unprognostic (4.20e-3)" "unprognostic (6.24e-2)" "unprognostic (7.02e-2)" "unprognostic (2.77e-2)" "unprognostic (7.34e-2)" "unprognostic (8.33e-2)" "unprognostic (7.74e-2)" "unprognostic (1.95e-2)" "unprognostic (1.98e-2)" "unprognostic (2.44e-1)" "unprognostic (3.30e-2)" "unprognostic (4.63e-2)" "unprognostic (2.72e-2)" "unprognostic (1.11e-1)" "unprognostic (1.76e-3)" "unprognostic (1.45e-1)" FAM124B FLJ22746 ENSG00000124019 "Family with sequence similarity 124 member B" Q9H5Z6 2 224378698-224402107 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 8.0" "Cell type enhanced" "Detected in some" "Erythrocyte progenitors: 51.6;Hematopoietic stem cells: 62.1;Innate lymphoid cells: 13.3;Mast cells: 11.1;Megakaryocyte progenitors: 27.0;Megakaryocyte-Erythroid progenitors: 167.6;Vascular endothelial cells: 15.7" "Group enriched" "Detected in some" 4 "endothelial cell: 22.2;ependymal cell: 11.7" "Cancer enriched" "Detected in many" 8 "Testicular Germ Cell Tumor (TCGA): 15.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 29.7;eosinophil: 17.2" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in single" 7 "Leukemia: 3.8" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Skeletal muscle - Endothelial cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA070240 Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 46: Brainstem - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 28 Nucleoplasm Mitochondria "HPA070240: " "unprognostic (2.38e-2)" "unprognostic (9.49e-2)" "unprognostic (2.04e-1)" "unprognostic (3.18e-1)" "unprognostic (3.21e-1)" "potential prognostic favorable (6.09e-7)" "unprognostic (1.57e-3)" "unprognostic (4.70e-2)" "unprognostic (3.08e-2)" "unprognostic (5.14e-2)" "unprognostic (3.23e-1)" "unprognostic (1.22e-1)" "unprognostic (6.12e-2)" "unprognostic (4.49e-2)" "unprognostic (1.69e-2)" "unprognostic (3.37e-1)" "unprognostic (1.27e-1)" FAM131A "C3orf40, MGC21688" ENSG00000175182 "Family with sequence similarity 131 member A" Q6UXB0 3 184335926-184348421 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 96.5" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 63.8;Lactotrophs: 85.7;Somatotrophs: 60.9;Syncytiotrophoblasts: 54.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042800 Uncertain Approved "Nucleoli rim,Mitotic chromosome" Yes No "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 73: Brain - Neuronal signaling" "Cluster 29: Forebrain - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" "Nucleoli rim" "Mitotic chromosome" "HPA042800: " "unprognostic (1.29e-1)" "unprognostic (9.27e-2)" "unprognostic (1.93e-1)" "unprognostic (2.52e-2)" "unprognostic (2.00e-2)" "unprognostic (2.98e-1)" "unprognostic (1.27e-1)" "unprognostic (5.01e-2)" "unprognostic (1.21e-1)" "unprognostic (1.74e-2)" "unprognostic (1.64e-1)" "unprognostic (4.67e-2)" "unprognostic (3.89e-3)" "unprognostic (4.50e-3)" "unprognostic (1.10e-2)" "unprognostic (1.47e-1)" "unprognostic (7.77e-2)" "unprognostic (4.24e-2)" "potential prognostic favorable (5.85e-4)" "unprognostic (6.73e-2)" "unprognostic (6.33e-2)" "unprognostic (2.11e-1)" "unprognostic (5.01e-2)" "unprognostic (1.02e-2)" "unprognostic (1.83e-2)" "unprognostic (1.03e-1)" "unprognostic (1.08e-2)" "unprognostic (9.44e-3)" "unprognostic (1.69e-1)" "unprognostic (1.62e-1)" "unprognostic (8.07e-2)" FAM131B KIAA0773 ENSG00000159784 "Family with sequence similarity 131 member B" Q86XD5 7 143353400-143362770 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "brain: 55.1" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 18.0;Brain inhibitory neurons: 9.7;Decidual stromal cells: 4.8;Late spermatids: 6.9;Medullary thymic epithelial cells: 4.8;Megakaryocytes: 6.2;Oligodendrocyte progenitor cells: 12.7;Oligodendrocytes: 30.9;Other brain neurons: 8.4;Paneth cells: 3.9;Retinal amacrine cells: 5.2;Retinal ganglion cells: 3.9" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in many" 12 "Glioblastoma Multiforme (TCGA): 28.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "colorectal cancer: 5.8;Gallbladder cancer: 12.0;Neuroblastoma: 15.0" "Minor Salivary Gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021371, HPA029992" Enhanced Nucleoplasm,Cytosol NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 53: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 1 Nucleoplasm Cytosol "HPA021371: , HPA029992: " "unprognostic (6.89e-2)" "unprognostic (8.00e-2)" "unprognostic (4.36e-2)" "unprognostic (3.79e-2)" "unprognostic (3.02e-1)" "unprognostic (1.26e-1)" "unprognostic (2.11e-1)" "unprognostic (2.20e-1)" "unprognostic (1.57e-2)" "unprognostic (1.04e-1)" "unprognostic (2.40e-2)" "unprognostic (1.70e-1)" FAM131C "C1orf117, FLJ36766" ENSG00000185519 "Family with sequence similarity 131 member C" Q96AQ9 1 16057769-16073651 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 72.1;kidney: 19.0" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 13.7;Early spermatids: 9.4;Epididymal clear cells: 30.6;Epididymal efferent duct ciliated cells: 12.2;Late spermatids: 9.6;Loop of henle epithelial cells: 16.4;Müller glia: 15.3;Pancreatic islet cells: 15.3;Renal collecting duct intercalated cells: 12.5;Respiratory ionocytes: 68.6;Retinal horizontal cells: 18.0" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 30.0;upper rhombic lip: 32.2" "Group enriched" "Detected in many" 4 "Kidney Chromophobe (TCGA): 25.9;Kidney Renal Clear Cell Carcinoma (TCGA): 8.3;Kidney Renal Papillary Cell Carcinoma (TCGA): 26.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031046 Uncertain Approved "Nucleoli,Intermediate filaments,Cytosol" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 25: Non-specific - Transcription" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 5 "Intermediate filaments, Cytosol" Nucleoli "HPA031046: " "unprognostic (4.76e-2)" "unprognostic (4.81e-2)" "unprognostic (4.65e-2)" "unprognostic (3.09e-1)" "unprognostic (2.23e-2)" "unprognostic (1.32e-1)" "unprognostic (5.45e-2)" "unprognostic (1.10e-2)" "unprognostic (4.86e-3)" "potential prognostic favorable (2.31e-4)" "unprognostic (1.15e-1)" "unprognostic (1.50e-2)" "unprognostic (2.58e-1)" "unprognostic (1.43e-1)" "potential prognostic unfavorable (9.02e-5)" "unprognostic (2.49e-1)" "unprognostic (1.15e-1)" "unprognostic (4.32e-2)" FAM133A "CT115, FLJ37659, RP1-32F7.2" ENSG00000179083 "Family with sequence similarity 133 member A" Q8N9E0 X 93674013-93712274 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.9;testis: 7.3" "Cell type enriched" "Detected in some" 8 "Sertoli cells: 385.6" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 3.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Gallbladder cancer: 27.2;Myeloma: 13.5" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Prostate - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in all" "HPA066175, HPA069513" Approved Nucleoplasm,Nucleoli NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 20: Myeloma - Immune response" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 58 Nucleoli Nucleoplasm "HPA066175: , HPA069513: " "unprognostic (1.64e-2)" "potential prognostic favorable (6.87e-4)" "unprognostic (2.22e-3)" "potential prognostic unfavorable (1.15e-4)" "unprognostic (3.81e-2)" "unprognostic (1.10e-1)" "unprognostic (3.63e-2)" "unprognostic (8.76e-2)" "unprognostic (1.16e-1)" "unprognostic (2.93e-1)" FAM133B MGC40405 ENSG00000234545 "Family with sequence similarity 133 member B" Q5BKY9 7 92560758-92590393 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066175, HPA069513" Enhanced Nucleoplasm,Nucleoli NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 34: Non-specific - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 51: Secretory epithelial cells - Mixed function" Nucleoli Nucleoplasm "HPA066175: , HPA069513: " "unprognostic (1.01e-3)" "unprognostic (1.30e-1)" "unprognostic (6.70e-2)" "unprognostic (5.99e-2)" "unprognostic (1.64e-1)" "unprognostic (1.07e-1)" "unprognostic (2.17e-1)" "potential prognostic favorable (3.44e-4)" "unprognostic (3.63e-1)" "unprognostic (3.78e-2)" "unprognostic (5.87e-3)" "unprognostic (1.06e-1)" "unprognostic (2.15e-1)" "unprognostic (3.53e-2)" "unprognostic (4.53e-2)" "unprognostic (2.11e-1)" "unprognostic (6.42e-2)" "unprognostic (1.29e-2)" "unprognostic (1.13e-1)" "unprognostic (1.19e-1)" "unprognostic (5.54e-2)" "unprognostic (1.14e-1)" "unprognostic (1.13e-2)" "unprognostic (1.88e-1)" "unprognostic (9.23e-2)" "unprognostic (6.56e-2)" "unprognostic (1.88e-2)" "unprognostic (1.10e-1)" "unprognostic (4.55e-1)" "unprognostic (3.24e-1)" "unprognostic (2.87e-1)" FAM135A "FLJ20176, KIAA1411" ENSG00000082269 "Family with sequence similarity 135 member A" Q9P2D6 6 70412941-70561174 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 28.1" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 770.5;Prostatic glandular cells: 762.7;Retinal horizontal cells: 1274.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031743, HPA031744" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 8 Nucleoplasm Cytosol "HPA031743: , HPA031744: " "unprognostic (4.05e-1)" "unprognostic (1.04e-1)" "unprognostic (1.34e-2)" "unprognostic (1.82e-1)" "unprognostic (5.92e-3)" "unprognostic (1.65e-1)" "unprognostic (2.34e-2)" "unprognostic (5.22e-2)" "unprognostic (1.15e-1)" "potential prognostic unfavorable (4.86e-5)" "validated prognostic favorable (2.23e-5)" "validated prognostic favorable (7.37e-4)" "unprognostic (2.47e-1)" "unprognostic (3.56e-1)" "unprognostic (7.28e-2)" "unprognostic (2.95e-2)" "unprognostic (2.96e-1)" "unprognostic (2.37e-1)" "unprognostic (2.75e-1)" "unprognostic (5.78e-2)" "unprognostic (2.37e-2)" "unprognostic (2.67e-1)" "unprognostic (2.20e-1)" "unprognostic (1.28e-3)" "unprognostic (1.59e-1)" "unprognostic (3.14e-1)" "unprognostic (3.35e-1)" "unprognostic (4.89e-1)" "unprognostic (5.39e-2)" "unprognostic (5.56e-2)" FAM135B C8ORFK32 ENSG00000147724 "Family with sequence similarity 135 member B" Q49AJ0 8 138130023-138497261 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "adrenal gland: 2.5;brain: 6.6;retina: 9.1;testis: 3.6" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 159.6;Bergmann glia: 163.3;Brain excitatory neurons: 210.0;Brain inhibitory neurons: 262.3;Cone photoreceptor cells: 604.5;Early spermatids: 517.9;Ependymal cells: 252.5;Lactotrophs: 230.7;Late primary spermatocytes: 226.0;Late spermatids: 210.7;Retinal bipolar cells: 706.4;Thyrotrophs: 270.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in single" "Glioblastoma Multiforme (TCGA): 2.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Enteric glia cells, Pancreas - Alpha cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA023911, HPA023950, HPA024815" Uncertain Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 3 "Nuclear membrane" Nucleoplasm "HPA023911: , HPA023950: , HPA024815: " "unprognostic (1.10e-1)" "unprognostic (2.09e-1)" "unprognostic (1.11e-2)" FAM136A FLJ14668 ENSG00000035141 "Family with sequence similarity 136 member A" Q96C01 2 70295976-70302067 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 199.3;Oocytes: 161.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030103, HPA030104" Enhanced Approved Mitochondria NA NA "Cluster 32: Basophils - Transcription" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 24: Neurons - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 44: Plasma cells - Antibody production & secretion" 22 Mitochondria "HPA030103: , HPA030104: " "unprognostic (3.09e-2)" "unprognostic (3.69e-2)" "unprognostic (7.67e-2)" "unprognostic (4.08e-2)" "unprognostic (1.92e-1)" "unprognostic (3.07e-2)" "unprognostic (1.95e-1)" "unprognostic (1.08e-2)" "unprognostic (1.73e-2)" "unprognostic (6.78e-2)" "unprognostic (2.35e-2)" "unprognostic (1.79e-2)" "unprognostic (5.56e-3)" "validated prognostic unfavorable (9.76e-7)" "validated prognostic unfavorable (1.58e-7)" "potential prognostic unfavorable (1.47e-4)" "unprognostic (1.42e-1)" "unprognostic (1.54e-2)" "unprognostic (5.88e-2)" "unprognostic (1.15e-2)" "unprognostic (2.65e-2)" "unprognostic (4.18e-3)" "unprognostic (1.93e-3)" "unprognostic (2.27e-1)" "unprognostic (2.22e-1)" "unprognostic (2.93e-1)" "unprognostic (2.11e-1)" "unprognostic (2.22e-2)" "unprognostic (4.32e-1)" "unprognostic (3.20e-1)" "unprognostic (2.89e-1)" FAM13A "ARHGAP48, FAM13A1, KIAA0914" ENSG00000138640 "Family with sequence similarity 13 member A" O94988 4 88725955-89111398 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 918.1;Pancreatic acinar cells: 2377.8;Pituicytes/FSCs: 1236.3;Syncytiotrophoblasts: 1030.2;Transitional alveolar cells: 726.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038108, HPA038109" Uncertain Approved "Nucleoli,Cell Junctions,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 5: Non-specific - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 89: Adipocytes - Lipid metabolism" 10 Cytosol "Nucleoli, Cell Junctions" "HPA038108: , HPA038109: " "unprognostic (6.52e-2)" "unprognostic (1.64e-1)" "unprognostic (1.32e-1)" "unprognostic (1.45e-1)" "unprognostic (3.48e-2)" "unprognostic (1.39e-1)" "unprognostic (3.07e-1)" "unprognostic (2.87e-2)" "unprognostic (2.54e-2)" "unprognostic (4.90e-3)" "potential prognostic favorable (1.57e-4)" "unprognostic (1.78e-3)" "unprognostic (5.24e-2)" "unprognostic (3.22e-1)" "unprognostic (1.82e-1)" "unprognostic (4.46e-1)" "unprognostic (4.80e-3)" "unprognostic (2.95e-2)" "unprognostic (4.08e-2)" "unprognostic (1.19e-1)" "unprognostic (3.76e-1)" "unprognostic (8.60e-3)" "unprognostic (1.88e-1)" "unprognostic (2.58e-1)" "unprognostic (1.92e-2)" "unprognostic (3.31e-1)" "unprognostic (5.02e-2)" "unprognostic (2.58e-2)" "unprognostic (1.17e-1)" "unprognostic (4.17e-1)" "unprognostic (1.57e-1)" FAM13B "ARHGAP49, C5orf5, FAM13B1, KHCHP, N61" ENSG00000031003 "Family with sequence similarity 13 member B" Q9NYF5 5 137937960-138051961 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 480.6;Sertoli cells: 485.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036525, HPA041819, HPA071936" Uncertain Approved Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 4 Nucleoplasm "HPA036525: , HPA041819: , HPA071936: " "unprognostic (2.96e-3)" "unprognostic (9.60e-3)" "unprognostic (1.64e-1)" "unprognostic (1.32e-1)" "unprognostic (1.02e-1)" "unprognostic (1.15e-1)" "unprognostic (2.36e-2)" "unprognostic (1.42e-1)" "unprognostic (2.56e-2)" "unprognostic (3.23e-2)" "validated prognostic favorable (8.82e-8)" "validated prognostic favorable (9.73e-4)" "unprognostic (8.69e-2)" "unprognostic (3.02e-2)" "unprognostic (1.27e-1)" "unprognostic (3.16e-3)" "unprognostic (1.35e-1)" "unprognostic (1.94e-1)" "unprognostic (3.78e-2)" "unprognostic (2.23e-1)" "unprognostic (9.11e-3)" "unprognostic (6.82e-2)" "unprognostic (1.28e-2)" "unprognostic (2.71e-1)" "unprognostic (1.24e-2)" "unprognostic (8.38e-2)" "unprognostic (1.19e-1)" "unprognostic (3.17e-1)" "unprognostic (3.72e-1)" "unprognostic (6.56e-2)" "unprognostic (2.63e-1)" FAM13C FAM13C1 ENSG00000148541 "Family with sequence similarity 13 member C" Q8NE31 10 59246130-59363181 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 38.2" "Cell type enhanced" "Detected in many" "Myonuclei: 149.6;Oligodendrocytes: 571.7;Pericytes: 158.2;Prostatic glandular cells: 181.2;Renal collecting duct intercalated cells: 268.9;Salivary ionocytes: 248.6;Thymic myoid cells: 157.7" "Cell type enhanced" "Detected in all" "oligodendrocyte: 758.6" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 22.0;Prostate Adenocarcinoma (TCGA): 21.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 7.4;Rhabdoid: 12.2" "Liver - Hepatic stellate cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037888 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 3: Rhabdoid - Membrane components" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 12 "Nucleoplasm, Cytosol" "HPA037888: " "unprognostic (1.03e-3)" "unprognostic (1.98e-1)" "potential prognostic favorable (6.26e-4)" "unprognostic (2.01e-1)" "unprognostic (1.85e-2)" "unprognostic (2.66e-1)" "unprognostic (1.05e-3)" "unprognostic (3.19e-2)" "unprognostic (5.45e-2)" "validated prognostic favorable (3.74e-4)" "validated prognostic favorable (3.14e-4)" "unprognostic (5.40e-2)" "unprognostic (3.42e-2)" "unprognostic (3.97e-2)" "unprognostic (3.93e-2)" "unprognostic (1.25e-1)" "unprognostic (9.16e-2)" "unprognostic (3.93e-2)" "unprognostic (1.13e-1)" "unprognostic (3.66e-1)" "unprognostic (9.74e-3)" "unprognostic (1.61e-1)" "unprognostic (1.79e-1)" "unprognostic (1.67e-2)" "unprognostic (6.81e-2)" "unprognostic (1.98e-2)" "unprognostic (2.93e-1)" "unprognostic (3.17e-2)" "unprognostic (2.70e-1)" FAM149A "DKFZP564J102, MST119, MSTP119" ENSG00000109794 "Family with sequence similarity 149 member A" A5PLN7 4 186104419-186175337 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 46.8" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 150.2;Cone photoreceptor cells: 182.2;Microglia: 619.6;Pancreatic duct cells: 168.2;Respiratory ciliated cells: 146.2;Rod photoreceptor cells: 160.4" "Cell type enriched" "Detected in all" 5 "central nervous system macrophage: 729.4" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 42.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.2" "Lineage enriched" "Detected in single" 4 "T-cells: 1.2" "Cancer enriched" "Detected in many" 4 "Kidney cancer: 21.1" "Liver - Hepatocytes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044019, HPA055004" Uncertain Approved "Golgi apparatus" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 36: Brain & Liver - Signaling" "Cluster 29: Forebrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" "Golgi apparatus" "HPA044019: , HPA055004: " "unprognostic (7.79e-2)" "unprognostic (1.14e-2)" "unprognostic (2.10e-3)" "unprognostic (4.06e-2)" "unprognostic (3.68e-2)" "unprognostic (7.41e-2)" "unprognostic (1.07e-1)" "unprognostic (1.03e-1)" "unprognostic (7.12e-2)" "unprognostic (1.81e-1)" "unprognostic (1.03e-1)" "unprognostic (1.86e-2)" "potential prognostic favorable (5.31e-6)" "unprognostic (8.08e-3)" "unprognostic (2.01e-3)" "unprognostic (1.72e-1)" "unprognostic (1.50e-1)" "unprognostic (1.50e-2)" "unprognostic (6.91e-2)" "unprognostic (1.18e-1)" "unprognostic (1.56e-1)" "unprognostic (8.32e-2)" "unprognostic (6.35e-2)" "unprognostic (7.78e-2)" "unprognostic (3.36e-1)" "unprognostic (1.83e-1)" "unprognostic (2.19e-2)" "unprognostic (4.61e-2)" "unprognostic (8.52e-2)" "unprognostic (1.05e-1)" "unprognostic (4.99e-2)" FAM149B1 KIAA0974 ENSG00000138286 "Family with sequence similarity 149 member B1" Q96BN6 10 73168119-73244504 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039189, HPA039859" Uncertain Approved "Microtubules,Primary cilium,Cytosol" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "Microtubules, Primary cilium" Cytosol "HPA039189: , HPA039859: " "unprognostic (1.10e-1)" "unprognostic (2.50e-2)" "unprognostic (1.55e-1)" "unprognostic (6.32e-2)" "unprognostic (1.40e-1)" "unprognostic (1.41e-1)" "unprognostic (2.31e-1)" "potential prognostic favorable (8.82e-5)" "unprognostic (4.73e-2)" "unprognostic (4.35e-2)" "potential prognostic favorable (2.91e-7)" "unprognostic (5.42e-3)" "unprognostic (4.27e-2)" "unprognostic (2.11e-1)" "unprognostic (1.81e-1)" "unprognostic (2.70e-1)" "unprognostic (4.09e-2)" "unprognostic (4.77e-2)" "unprognostic (6.28e-2)" "unprognostic (5.36e-2)" "unprognostic (3.51e-2)" "unprognostic (6.52e-3)" "unprognostic (7.37e-2)" "unprognostic (6.28e-2)" "unprognostic (8.23e-2)" "unprognostic (1.21e-1)" "unprognostic (2.87e-2)" "unprognostic (1.71e-1)" "unprognostic (2.21e-1)" "unprognostic (8.60e-2)" "unprognostic (7.93e-2)" FAM151A "C1orf179, MGC27169" ENSG00000162391 "Family with sequence similarity 151 member A" Q8WW52 1 54609181-54623556 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "intestine: 68.2;kidney: 163.0" "Group enriched" "Detected in many" 5 "Cardiomyocytes: 233.8;Enterocytes: 469.9" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 16.8;ependymal cell: 12.9" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 15.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 2.7;Gastric cancer: 2.6;liver cancer: 2.7" "Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA016840 Approved NA NA 6900 "Cluster 72: Kidney - Transmembrane transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 18: Liver cancer - Metabolism" "Cluster 1: Enterocytes - Absorption and Digestion" "HPA016840: " "unprognostic (6.00e-2)" "unprognostic (1.61e-1)" "unprognostic (4.59e-2)" "unprognostic (8.48e-3)" "unprognostic (1.17e-1)" "unprognostic (1.21e-3)" "unprognostic (1.91e-2)" "unprognostic (8.79e-2)" "unprognostic (1.65e-1)" "unprognostic (4.87e-2)" "unprognostic (3.10e-1)" "unprognostic (3.33e-2)" "unprognostic (3.11e-1)" "unprognostic (3.30e-2)" "unprognostic (7.86e-2)" "unprognostic (2.20e-1)" FAM151B UNQ9217 ENSG00000152380 "Family with sequence similarity 151 member B" Q6UXP7 5 80487969-80542563 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.4" "Cell type enhanced" "Detected in many" "Ependymal cells: 53.9;Neutrophil progenitors: 179.2;Neutrophils: 88.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043805 Uncertain Approved Cytosol NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 15: Bone marrow - Innate immune response" "Cluster 29: Forebrain - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 1 Cytosol "HPA043805: " "unprognostic (6.42e-2)" "unprognostic (5.10e-1)" "unprognostic (2.84e-1)" "potential prognostic unfavorable (9.28e-4)" "unprognostic (3.75e-1)" "unprognostic (1.30e-1)" "unprognostic (4.84e-3)" "unprognostic (2.64e-1)" "unprognostic (1.56e-1)" "unprognostic (3.57e-2)" "unprognostic (2.12e-1)" "unprognostic (1.23e-1)" FAM153A NY-REN-7 ENSG00000170074 "Family with sequence similarity 153 member A" Q9UHL3 5 177707981-177784435 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 26.6" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 91.1;Brain inhibitory neurons: 50.4;Early spermatids: 133.1;Epicardial cells: 111.4;Gonadotrophs: 62.0;Granulosa cells: 94.9;Peritubular myoid cells: 46.7;Sertoli cells: 139.0;Somatotrophs: 113.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in single" "Kidney Renal Clear Cell Carcinoma (TCGA): 2.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 2.5;plasmacytoid DC: 1.8" "Group enriched" "Detected in many" 7 "dendritic cells: 1.8;T-cells: 2.5" "Cancer enhanced" "Detected in some" "Kidney cancer: 4.6" "Adipose visceral - Mesothelial cells" "HPA042585, HPA044022, HPA046691, HPA052337, HPA055498" Uncertain NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 34: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 35: Neurons - Synaptic function & neurogenesis" 2 "HPA042585: , HPA044022: , HPA046691: , HPA052337: , HPA055498: " "unprognostic (1.79e-2)" "unprognostic (1.02e-1)" "unprognostic (2.05e-1)" "unprognostic (2.22e-1)" FAM156A "PRO0659, TMEM29" ENSG00000268350 "Family with sequence similarity 156 member A" Q8NDB6 X 52926402-52995472 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 30.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA056640, HPA056643" Approved NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 64: Non-specific - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 7: Non-specific - Transcription" 6 "HPA056640: , HPA056643: " "unprognostic (4.15e-2)" "unprognostic (1.30e-1)" "unprognostic (1.72e-2)" "unprognostic (2.26e-2)" "unprognostic (1.50e-1)" "unprognostic (2.40e-1)" "unprognostic (1.60e-1)" "unprognostic (1.25e-2)" "unprognostic (1.76e-1)" "unprognostic (2.44e-3)" "unprognostic (3.38e-1)" "unprognostic (1.27e-1)" "unprognostic (4.74e-3)" "unprognostic (1.71e-2)" "unprognostic (2.37e-2)" "unprognostic (5.97e-2)" "unprognostic (4.18e-2)" "unprognostic (2.11e-2)" "unprognostic (3.39e-3)" "unprognostic (3.59e-2)" "unprognostic (1.09e-1)" "unprognostic (2.85e-3)" "unprognostic (6.31e-2)" "unprognostic (1.79e-2)" "unprognostic (1.11e-1)" "unprognostic (1.65e-2)" "unprognostic (1.17e-2)" FAM156B TMEM29B ENSG00000179304 "Family with sequence similarity 156 member B" Q8NDB6 X 52891306-52908560 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "HPA056640, HPA056643" Uncertain NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 64: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 6 "HPA056640: , HPA056643: " "unprognostic (4.15e-2)" "unprognostic (4.02e-2)" "unprognostic (3.67e-3)" "unprognostic (1.68e-2)" "unprognostic (4.12e-2)" "unprognostic (1.04e-1)" "unprognostic (2.50e-1)" "unprognostic (1.70e-1)" "unprognostic (3.00e-1)" "potential prognostic unfavorable (5.66e-11)" "unprognostic (1.98e-3)" "unprognostic (1.04e-1)" "potential prognostic unfavorable (1.15e-4)" "unprognostic (2.41e-1)" "unprognostic (1.45e-2)" "unprognostic (2.45e-2)" "unprognostic (4.25e-3)" "unprognostic (1.89e-2)" "unprognostic (2.80e-3)" "unprognostic (1.10e-2)" "unprognostic (3.20e-3)" "unprognostic (4.40e-2)" "unprognostic (1.49e-1)" "unprognostic (2.35e-2)" "unprognostic (7.63e-2)" "unprognostic (2.12e-1)" "unprognostic (2.14e-1)" "unprognostic (5.49e-2)" "unprognostic (1.63e-2)" FAM161A "FLJ13305, RP28" ENSG00000170264 "FAM161 centrosomal protein A" Q3B820 2 61824848-61854143 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Sensory transduction, Vision" "Ciliopathy, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "retina: 26.9" "Cell type enhanced" "Detected in many" "Early spermatids: 157.4;Late primary spermatocytes: 168.2;Late spermatids: 474.9;Respiratory ciliated cells: 107.6;Retinal pigment epithelial cells: 162.0;Rod photoreceptor cells: 395.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032119, HPA064830" Approved Supported "Nucleoplasm,Golgi apparatus,Centrosome,Basal body,Cytosol,Flagellar centriole" NA Yes "Cluster 42: Retina - Visual perception" "Cluster 23: Choroid plexus - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 79: Photoreceptor cells - Phototransduction" 125 "Centrosome, Basal body, Flagellar centriole" "Nucleoplasm, Golgi apparatus, Cytosol" "HPA032119: , HPA064830: " "unprognostic (5.14e-2)" "unprognostic (2.67e-1)" "unprognostic (6.35e-2)" "unprognostic (1.02e-1)" "unprognostic (7.75e-2)" "unprognostic (2.74e-1)" "potential prognostic favorable (9.19e-7)" "unprognostic (4.63e-2)" "unprognostic (4.72e-3)" "unprognostic (2.69e-1)" "unprognostic (2.24e-1)" "unprognostic (1.91e-1)" "unprognostic (3.96e-3)" "unprognostic (3.61e-2)" "unprognostic (2.05e-1)" "unprognostic (2.26e-2)" "unprognostic (2.23e-1)" "unprognostic (3.48e-1)" "unprognostic (6.85e-3)" "unprognostic (2.65e-1)" FAM161B "C14orf44, FLJ31697" ENSG00000156050 "FAM161 centrosomal protein B" Q96MY7 14 73931501-73950414 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 35.3;Early spermatids: 85.7;Late spermatids: 195.4;Retinal ganglion cells: 34.8;Rod photoreceptor cells: 31.6" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Uterine Corpus Endometrial Carcinoma (TCGA): 35.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Bile duct cancer: 19.9" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019125 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 75: Ovary - Mixed function" "Cluster 24: Neurons - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 65: Non-specific - Cell growth & division" 54 "Nucleoplasm, Plasma membrane" "Vesicles, Cytosol" "HPA019125: " "unprognostic (1.98e-1)" "unprognostic (1.24e-1)" "unprognostic (1.94e-1)" "unprognostic (2.48e-2)" "unprognostic (7.66e-3)" "unprognostic (2.87e-1)" "unprognostic (1.22e-1)" "unprognostic (3.03e-1)" "unprognostic (2.73e-3)" "unprognostic (1.22e-2)" "unprognostic (3.34e-2)" "unprognostic (6.00e-3)" "unprognostic (3.29e-1)" "potential prognostic unfavorable (5.82e-4)" "unprognostic (6.09e-3)" "unprognostic (4.48e-2)" "unprognostic (1.13e-1)" "unprognostic (5.45e-2)" "unprognostic (3.29e-2)" "unprognostic (1.32e-1)" "unprognostic (1.91e-2)" "unprognostic (9.64e-2)" "unprognostic (3.67e-1)" "unprognostic (1.55e-1)" "unprognostic (2.90e-2)" "unprognostic (6.00e-2)" "unprognostic (9.77e-2)" "unprognostic (5.95e-2)" "unprognostic (4.56e-2)" "unprognostic (1.17e-3)" "unprognostic (3.18e-2)" FAM162A "C3orf28, E2IG5" ENSG00000114023 "Family with sequence similarity 162 member A" Q96A26 3 122384161-122412334 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 541.8;Esophageal apical cells: 1354.6;Esophageal suprabasal cells: 1359.5;Parietal cells: 567.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary gland basal cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035856, HPA075611" Approved Supported Mitochondria NA NA 17000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 70: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 15: Kidney cancer - Membrane components" "Cluster 85: Squamous epithelial cells - Keratinization" 16 Mitochondria "HPA035856: , HPA075611: " "unprognostic (1.23e-1)" "unprognostic (7.20e-2)" "unprognostic (9.61e-2)" "unprognostic (7.03e-2)" "unprognostic (2.60e-2)" "unprognostic (2.81e-2)" "unprognostic (6.15e-2)" "unprognostic (6.05e-2)" "unprognostic (1.59e-1)" "unprognostic (3.86e-3)" "unprognostic (5.44e-2)" "unprognostic (1.83e-1)" "unprognostic (2.65e-2)" "unprognostic (6.13e-2)" "unprognostic (6.43e-2)" "unprognostic (9.24e-3)" "unprognostic (1.28e-2)" "unprognostic (1.29e-2)" "unprognostic (3.10e-1)" "unprognostic (1.72e-1)" "unprognostic (3.57e-2)" "potential prognostic unfavorable (9.12e-4)" "unprognostic (7.29e-2)" "unprognostic (6.98e-3)" "unprognostic (8.08e-2)" "potential prognostic unfavorable (5.49e-4)" "unprognostic (4.29e-2)" "unprognostic (3.67e-1)" "unprognostic (2.62e-1)" "unprognostic (1.59e-3)" "unprognostic (5.85e-2)" FAM162B "bA86F4.2, C6orf189" ENSG00000183807 "Family with sequence similarity 162 member B" Q5T6X4 6 116752197-116765719 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 61.2" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 159.6;Decidual stromal cells: 35.1;Fibro-adipogenic progenitors: 48.7;Pericytes: 206.6;Salivary ionocytes: 297.8;Vascular smooth muscle cells: 58.2" "Cell type enriched" "Detected in many" 4 "pericyte: 269.0" "Cancer enriched" "Detected in many" 13 "Testicular Germ Cell Tumor (TCGA): 47.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Neuroblastoma: 7.7;testis cancer: 4.3" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA036112, HPA060342" Enhanced NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 53: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 110: Mural cells - ECM organization" "HPA036112: , HPA060342: " "unprognostic (4.68e-2)" "unprognostic (1.00e-1)" "unprognostic (4.30e-3)" "unprognostic (3.31e-1)" "unprognostic (1.74e-1)" "unprognostic (3.50e-3)" "unprognostic (1.89e-3)" "potential prognostic favorable (6.20e-5)" "unprognostic (2.01e-1)" "unprognostic (2.71e-1)" "unprognostic (1.77e-2)" "unprognostic (6.69e-2)" "unprognostic (2.31e-2)" "unprognostic (9.40e-2)" "unprognostic (8.19e-2)" "unprognostic (3.26e-2)" "unprognostic (1.51e-3)" "unprognostic (4.00e-2)" "unprognostic (3.70e-2)" "unprognostic (2.15e-3)" "unprognostic (1.69e-1)" "unprognostic (1.06e-2)" "unprognostic (8.97e-2)" FAM163A "C1orf76, MGC16664, NDSP" ENSG00000143340 "Family with sequence similarity 163 member A" Q96GL9 1 179743291-179816198 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 14.9;pituitary gland: 29.7;testis: 12.5" "Group enriched" "Detected in some" 4 "Lactotrophs: 923.4;Somatotrophs: 490.4" "Cell type enhanced" "Detected in many" "lower rhombic lip: 164.6" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in all" "pons: 44.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 15 "Adrenocortical cancer: 45.6;Neuroblastoma: 56.7" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Pituitary gland - Lactotropes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 80: Thymus - Adaptive immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 26 "unprognostic (7.00e-3)" "unprognostic (1.16e-2)" "unprognostic (2.36e-1)" FAM163B C9orf166 ENSG00000196990 "Family with sequence similarity 163 member B" P0C2L3 9 133577081-133609389 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 61.2" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 31.9;Brain excitatory neurons: 22.2;Brain inhibitory neurons: 27.5;Colonocytes: 6.9;Early spermatids: 20.2;Hepatic stellate cells: 25.8;Late spermatids: 50.6;Other brain neurons: 11.6" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in single" 7 "Glioblastoma Multiforme (TCGA): 5.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Neuroblastoma: 12.9" "Adrenal gland - Adrenal medulla cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067336 Enhanced Approved "Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 35: Neurons - Synaptic function & neurogenesis" 3 "Nuclear bodies, Plasma membrane, Cytosol" "HPA067336: " "unprognostic (3.32e-2)" "unprognostic (5.14e-3)" "potential prognostic favorable (1.44e-4)" FAM166A ENSG00000188163 "Family with sequence similarity 166 member A" Q6J272 9 137243584-137247770 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 31 "testis: 56.7" "Group enriched" "Detected in some" 14 "Early spermatids: 772.3;Late spermatids: 2031.4" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 8 "Uterine Corpus Endometrial Carcinoma (TCGA): 3.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA023307 Enhanced Approved "Mid piece,Principal piece,End piece" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 5 "Mid piece, Principal piece, End piece" "HPA023307: " "unprognostic (1.94e-1)" "unprognostic (1.20e-2)" "unprognostic (1.37e-1)" FAM166B ENSG00000215187 "Family with sequence similarity 166 member B" A8MTA8 9 35561831-35563899 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 474.8;skeletal muscle: 299.2" "Cell type enhanced" "Detected in some" "Adrenal cortex cells: 52.7;Endometrial ciliated cells: 122.0;Ependymal cells: 71.4;Epididymal efferent duct ciliated cells: 285.4;Fallopian tube ciliated cells: 235.5;Myonuclei: 33.8;Respiratory ciliated cells: 111.7" "Cell type enriched" "Detected in some" 6 "ependymal cell: 92.6" "Cancer enhanced" "Detected in some" "Ovary Serous Cystadenocarcinoma (TCGA): 3.1;Uterine Corpus Endometrial Carcinoma (TCGA): 4.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Lung - Respiratory ciliated cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA045540 Enhanced NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 3: Choroid plexus - Cilium" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 107: Ciliated cells - Cilia assembly & function" "HPA045540: " "unprognostic (7.15e-2)" "unprognostic (5.09e-2)" "unprognostic (2.52e-1)" "unprognostic (1.17e-1)" "unprognostic (5.37e-2)" "unprognostic (7.62e-2)" "unprognostic (3.63e-3)" "unprognostic (4.11e-3)" "unprognostic (2.52e-2)" FAM166C "C2orf70, LOC339778" ENSG00000173557 "Family with sequence similarity 166 member C" A6NJV1 2 26562585-26579532 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 8.2;fallopian tube: 7.1;testis: 25.3" "Cell type enhanced" "Detected in some" "Early spermatids: 155.5;Epididymal efferent duct ciliated cells: 38.2;Fallopian tube ciliated cells: 44.8;Late primary spermatocytes: 103.8;Late spermatids: 610.5" "Group enriched" "Detected in some" 13 "choroid plexus epithelial cell: 9.2;ependymal cell: 26.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 4.5" "Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA062453 Enhanced Uncertain "Nuclear membrane,Vesicles" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 11: Neuronal - Sensory perception" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" "Nuclear membrane, Vesicles" "HPA062453: " "unprognostic (4.48e-2)" "unprognostic (1.17e-1)" "unprognostic (1.44e-2)" "unprognostic (1.13e-2)" "unprognostic (1.79e-2)" "unprognostic (1.70e-2)" "unprognostic (2.71e-2)" "unprognostic (4.14e-1)" "unprognostic (1.12e-2)" "unprognostic (7.80e-3)" "unprognostic (2.79e-2)" "unprognostic (1.37e-1)" "unprognostic (3.08e-1)" "unprognostic (2.23e-1)" "unprognostic (5.29e-1)" "unprognostic (2.34e-3)" "unprognostic (1.83e-2)" FAM167A "C8orf13, DIORA-1" ENSG00000154319 "Family with sequence similarity 167 member A" Q96KS9 8 11421476-11475908 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.9;thyroid gland: 49.9" "Cell type enhanced" "Detected in some" "Astrocytes: 32.4;Basal prostatic cells: 6.9;Bergmann glia: 43.3;Choroid plexus epithelial cells: 17.7;Ependymal cells: 9.1;Late spermatids: 8.3;Loop of henle epithelial cells: 8.6;Mucous neck cells: 7.9;Renal collecting duct principal cells: 6.1" "Cell type enhanced" "Detected in many" "astrocyte: 39.3;Bergmann glia: 54.9" "Group enriched" "Detected in many" 4 "Glioblastoma Multiforme (TCGA): 16.1;Thyroid Carcinoma (TCGA): 29.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.2" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Neuroblastoma: 32.4" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Lung - Alveolar cells type 1, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA023915, HPA030426" Approved Approved Mitochondria NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 33: Thyroid gland - Tissue development" "Cluster 44: Non-specific - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 28: Astrocytes - Homeostasis & neuron support" 45 Mitochondria "HPA023915: , HPA030426: " "unprognostic (3.90e-2)" "unprognostic (1.04e-1)" "unprognostic (3.31e-1)" "unprognostic (2.67e-2)" "unprognostic (2.59e-1)" "unprognostic (7.74e-2)" "unprognostic (2.00e-2)" "unprognostic (1.18e-2)" "unprognostic (2.09e-1)" "potential prognostic unfavorable (9.79e-5)" "unprognostic (1.11e-1)" "unprognostic (2.57e-2)" "unprognostic (1.54e-2)" "unprognostic (7.75e-2)" "unprognostic (2.47e-1)" "unprognostic (6.03e-3)" "unprognostic (2.17e-1)" "unprognostic (2.07e-1)" "unprognostic (8.59e-2)" "unprognostic (3.00e-1)" "unprognostic (4.42e-2)" "unprognostic (4.32e-2)" "unprognostic (1.18e-1)" "unprognostic (8.27e-2)" "unprognostic (1.50e-1)" "unprognostic (1.42e-2)" "unprognostic (6.71e-2)" FAM167B "C1orf90, DIORA-2, MGC10820" ENSG00000183615 "Family with sequence similarity 167 member B" Q9BTA0 1 32247222-32248856 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 44.4" "Cell type enriched" "Detected in some" 4 "Vascular endothelial cells: 92.5" "Group enriched" "Detected in some" 4 "endothelial cell: 8.1;ependymal cell: 2.6;vascular associated smooth muscle cell: 2.5" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 82.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.7" "Lineage enriched" "Detected in single" 5 "T-cells: 1.7" "Cancer enriched" "Detected in many" 6 "skin cancer: 47.4" "Adipose visceral - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in some" "Region enhanced" "Detected in single" "cerebellum: 1.0" "HPA029398, HPA062074" Uncertain Approved "Actin filaments" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 47: Endothelial cells - Vasculature" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "Actin filaments" "HPA029398: , HPA062074: " "unprognostic (4.56e-1)" "unprognostic (1.21e-1)" "unprognostic (2.11e-1)" "unprognostic (5.46e-3)" "unprognostic (4.81e-3)" "unprognostic (8.02e-2)" "unprognostic (2.03e-3)" "unprognostic (1.14e-1)" "unprognostic (5.79e-3)" "unprognostic (6.27e-3)" "potential prognostic favorable (4.61e-4)" "unprognostic (4.13e-3)" "unprognostic (1.01e-1)" "unprognostic (1.55e-2)" "potential prognostic favorable (6.42e-4)" "unprognostic (2.13e-1)" "unprognostic (7.93e-3)" "unprognostic (3.36e-2)" "unprognostic (1.80e-1)" "unprognostic (1.48e-2)" "unprognostic (9.24e-2)" "unprognostic (2.04e-2)" "unprognostic (1.03e-1)" "unprognostic (1.15e-1)" "unprognostic (7.55e-2)" "unprognostic (6.15e-2)" "unprognostic (7.74e-3)" "unprognostic (5.29e-3)" "unprognostic (1.64e-1)" "unprognostic (2.16e-1)" "unprognostic (6.74e-3)" FAM168A "KIAA0280, TCRP1" ENSG00000054965 "Family with sequence similarity 168 member A" Q92567 11 73400487-73598189 "Disease related genes, Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 6.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Pituitary gland - Undifferentiated cells (Pituitary gland), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037580 Enhanced Approved Nucleoplasm NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 23 Nucleoplasm "HPA037580: " "unprognostic (2.74e-3)" "unprognostic (2.82e-1)" "unprognostic (3.31e-1)" "unprognostic (5.16e-2)" "unprognostic (2.46e-2)" "potential prognostic unfavorable (8.87e-4)" "unprognostic (3.11e-2)" "unprognostic (7.39e-2)" "unprognostic (1.07e-1)" "unprognostic (3.28e-3)" "potential prognostic favorable (1.09e-5)" "unprognostic (3.82e-2)" "unprognostic (1.19e-1)" "unprognostic (1.22e-2)" "unprognostic (8.69e-2)" "unprognostic (3.86e-2)" "unprognostic (6.40e-3)" "unprognostic (8.10e-2)" "unprognostic (2.46e-1)" "unprognostic (1.33e-2)" "unprognostic (3.70e-2)" "unprognostic (2.76e-1)" "unprognostic (1.94e-1)" "unprognostic (3.59e-1)" "unprognostic (1.04e-1)" "unprognostic (1.26e-1)" "unprognostic (2.06e-1)" "unprognostic (6.71e-2)" "unprognostic (4.85e-2)" "unprognostic (3.52e-2)" "unprognostic (2.39e-2)" FAM168B "KIAA0280L, MANI" ENSG00000152102 "Family with sequence similarity 168 member B" A1KXE4 2 131047876-131093460 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Prostate - Smooth muscle cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043778, HPA061659" Enhanced NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 33: Neurons - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 1 "HPA043778: , HPA061659: " "unprognostic (4.21e-2)" "unprognostic (1.16e-1)" "unprognostic (5.74e-2)" "unprognostic (8.31e-3)" "unprognostic (2.15e-1)" "unprognostic (1.02e-1)" "unprognostic (6.17e-2)" "unprognostic (2.07e-2)" "unprognostic (1.21e-2)" "unprognostic (3.20e-2)" "validated prognostic favorable (5.29e-7)" "validated prognostic favorable (3.57e-4)" "unprognostic (3.35e-1)" "unprognostic (2.92e-3)" "potential prognostic unfavorable (8.92e-4)" "unprognostic (1.28e-2)" "unprognostic (9.83e-2)" "unprognostic (1.02e-1)" "unprognostic (4.68e-2)" "unprognostic (6.91e-2)" "unprognostic (7.82e-2)" "unprognostic (1.04e-1)" "unprognostic (2.33e-1)" "unprognostic (2.63e-1)" "unprognostic (1.08e-2)" "unprognostic (1.22e-1)" "unprognostic (7.71e-2)" "unprognostic (2.60e-1)" "unprognostic (4.23e-1)" "unprognostic (9.63e-2)" "unprognostic (2.87e-1)" FAM169A "KIAA0888, SLAP75" ENSG00000198780 "Family with sequence similarity 169 member A" Q9Y6X4 5 74777574-74866966 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 72.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 383.0;Müller glia: 437.9;Renal collecting duct principal cells: 182.0;Retinal amacrine cells: 246.7;Retinal bipolar cells: 299.0;Retinal horizontal cells: 188.3;Rod photoreceptor cells: 731.6" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 9.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Lineage enriched" "Detected in single" 4 "T-cells: 1.1" "Low cancer specificity" "Detected in many" "Skin - Inner root sheath cells, Skin - Outer root sheath cells, Testis - Early spermatids, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041574 Enhanced Supported "Nuclear membrane,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 42: Retina - Visual perception" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" 7 "Nuclear membrane, Cytosol" "HPA041574: " "unprognostic (1.50e-2)" "unprognostic (5.69e-2)" "unprognostic (1.09e-1)" "unprognostic (3.64e-3)" "unprognostic (3.57e-1)" "unprognostic (2.77e-1)" "unprognostic (5.61e-2)" "unprognostic (1.24e-2)" "potential prognostic unfavorable (6.12e-4)" "unprognostic (2.74e-1)" "unprognostic (8.74e-2)" "unprognostic (2.63e-1)" "unprognostic (3.28e-1)" "unprognostic (2.45e-2)" "unprognostic (1.50e-1)" "unprognostic (3.10e-1)" "unprognostic (7.09e-2)" "unprognostic (1.80e-2)" "unprognostic (1.85e-2)" "unprognostic (3.53e-1)" "unprognostic (1.08e-1)" "unprognostic (2.19e-3)" "unprognostic (1.05e-2)" FAM170A ZNFD ENSG00000164334 "Family with sequence similarity 170 member A" A1A519 5 119629558-119635822 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 52 "testis: 13.4" "Cell type enriched" "Detected in some" 6 "Late primary spermatocytes: 96.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA037900, HPA037902" Enhanced NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" "HPA037900: , HPA037902: " FAM170B "AC084727.4, C10orf73" ENSG00000172538 "Family with sequence similarity 170 member B" A6NMN3 10 49131154-49134021 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 61 "testis: 6.1" "Cell type enriched" "Detected in some" 4 "Early spermatids: 117.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 20 "eosinophil: 1.9" "Lineage enriched" "Detected in single" 20 "granulocytes: 1.9" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043899, HPA050610" Uncertain NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 55: Lymphoma - Immune response" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" "HPA043899: , HPA050610: " FAM171A1 "APCN, C10orf38, FLJ12884" ENSG00000148468 "Family with sequence similarity 171 member A1" Q5VUB5 10 15211643-15371289 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 97.5" "Cell type enhanced" "Detected in many" "Astrocytes: 413.6;Bergmann glia: 251.9;Brain inhibitory neurons: 219.9;Cholangiocytes: 282.4;Distal convoluted tubule cells: 351.3;Loop of henle epithelial cells: 207.8;Oligodendrocytes: 220.4;Renal connecting tubule cells: 444.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 1.7;MAIT T-cell: 4.4;memory CD4 T-cell: 2.5;memory CD8 T-cell: 2.2;naive CD4 T-cell: 4.7;naive CD8 T-cell: 2.4" "Lineage enriched" "Detected in single" 19 "T-cells: 4.7" "Low cancer specificity" "Detected in many" "Spleen - Endothelial cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051345 Approved Approved "Nucleoplasm,Plasma membrane" NA NA 67000 "Cluster 11: T-cells - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 7 "Plasma membrane" Nucleoplasm "HPA051345: " "unprognostic (4.34e-3)" "unprognostic (1.49e-2)" "unprognostic (2.45e-3)" "unprognostic (3.64e-1)" "unprognostic (5.54e-2)" "unprognostic (2.02e-1)" "unprognostic (3.35e-1)" "potential prognostic favorable (6.10e-4)" "unprognostic (6.18e-2)" "unprognostic (3.54e-1)" "potential prognostic favorable (8.93e-4)" "unprognostic (5.87e-2)" "unprognostic (5.61e-3)" "unprognostic (1.14e-1)" "unprognostic (5.19e-2)" "unprognostic (2.83e-1)" "unprognostic (5.23e-2)" "unprognostic (2.24e-2)" "unprognostic (3.58e-2)" "unprognostic (2.71e-1)" "unprognostic (1.40e-1)" "unprognostic (3.13e-2)" "unprognostic (1.11e-2)" "unprognostic (1.47e-1)" "unprognostic (1.76e-2)" "unprognostic (7.59e-2)" "unprognostic (2.37e-1)" "unprognostic (3.21e-1)" "unprognostic (1.75e-1)" "potential prognostic unfavorable (2.50e-4)" "unprognostic (1.59e-1)" FAM171A2 MGC34829 ENSG00000161682 "Family with sequence similarity 171 member A2" A8MVW0 17 44353215-44363853 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.1;pituitary gland: 7.7" "Cell type enriched" "Detected in many" 4 "Müller glia: 143.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 21.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 15.4" "Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019770 Uncertain NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 11: Muller glia cells - Retinal homeostasis" 9 "HPA019770: " "unprognostic (7.43e-2)" "unprognostic (7.31e-3)" "unprognostic (1.11e-1)" "unprognostic (4.04e-1)" "unprognostic (9.55e-2)" "potential prognostic favorable (9.60e-4)" "unprognostic (4.15e-2)" "unprognostic (1.75e-1)" "potential prognostic unfavorable (4.15e-6)" "unprognostic (5.78e-2)" "unprognostic (2.19e-1)" "unprognostic (4.14e-2)" "unprognostic (3.12e-1)" "unprognostic (2.43e-3)" "unprognostic (3.25e-1)" "unprognostic (1.45e-2)" "unprognostic (1.85e-2)" "unprognostic (8.72e-2)" "unprognostic (3.78e-2)" "unprognostic (2.68e-1)" FAM171B "FLJ34104, KIAA1946" ENSG00000144369 "Family with sequence similarity 171 member B" Q6P995 2 186694060-186765959 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 66.4" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 276.6;Astrocytes: 387.8;Bergmann glia: 233.9;Brain excitatory neurons: 150.4;Brain inhibitory neurons: 162.2;Corticotrophs: 178.2;Lactotrophs: 183.4;Oligodendrocyte progenitor cells: 154.4;Oligodendrocytes: 118.4;Other brain neurons: 143.4;Retinal bipolar cells: 329.0;Somatotrophs: 185.8;Thyrotrophs: 183.6" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 5 "Glioblastoma Multiforme (TCGA): 24.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Sarcoma: 39.8" "Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010529, HPA010639, HPA013434" Approved Approved Nucleoplasm,Nucleoli,Mitochondria,Cytosol NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "Nucleoplasm, Mitochondria" "Nucleoli, Cytosol" "HPA010529: , HPA010639: , HPA013434: " "unprognostic (1.19e-2)" "unprognostic (1.04e-1)" "unprognostic (7.52e-2)" "unprognostic (1.82e-2)" "unprognostic (9.05e-2)" "unprognostic (5.41e-2)" "unprognostic (4.39e-3)" "unprognostic (2.47e-2)" "unprognostic (1.31e-1)" "unprognostic (3.93e-3)" "unprognostic (1.09e-2)" "potential prognostic unfavorable (8.21e-7)" "unprognostic (1.60e-2)" "unprognostic (8.48e-2)" "unprognostic (8.01e-2)" "unprognostic (6.64e-2)" "unprognostic (9.72e-2)" "unprognostic (3.80e-1)" "unprognostic (2.96e-3)" "unprognostic (2.99e-2)" "unprognostic (2.72e-1)" "unprognostic (2.05e-2)" "unprognostic (1.08e-1)" "unprognostic (2.77e-3)" "unprognostic (1.46e-1)" "unprognostic (2.27e-3)" "unprognostic (9.68e-3)" FAM172A "C5orf21, DKFZP564D172, Toupee" ENSG00000113391 "Family with sequence similarity 172 member A" Q8WUF8 5 93617725-94111699 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 1725.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012299, HPA045505" Approved Supported Nucleoplasm,Cytosol "Intracellular and membrane" Other NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" 11 Nucleoplasm Cytosol "HPA012299: , HPA045505: " "unprognostic (1.22e-2)" "potential prognostic unfavorable (7.31e-4)" "unprognostic (3.82e-2)" "unprognostic (6.98e-2)" "unprognostic (2.09e-1)" "unprognostic (7.03e-2)" "unprognostic (3.05e-2)" "unprognostic (7.39e-2)" "unprognostic (1.98e-2)" "unprognostic (3.25e-3)" "potential prognostic favorable (3.87e-8)" "unprognostic (3.20e-3)" "unprognostic (1.19e-1)" "unprognostic (4.22e-2)" "unprognostic (8.33e-2)" "unprognostic (6.39e-2)" "unprognostic (1.53e-1)" "unprognostic (1.97e-2)" "unprognostic (1.73e-1)" "unprognostic (3.26e-3)" "unprognostic (5.18e-3)" "unprognostic (2.98e-2)" "unprognostic (1.05e-1)" "unprognostic (3.08e-1)" "unprognostic (4.92e-2)" "unprognostic (2.23e-1)" "unprognostic (1.30e-1)" "unprognostic (7.47e-2)" "unprognostic (7.53e-2)" "unprognostic (3.46e-3)" "unprognostic (1.75e-1)" FAM174A "NS5ATP6, TMEM157, UNQ1912" ENSG00000174132 "Family with sequence similarity 174 member A" Q8TBP5 5 100535374-100586741 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 245.1;Endometrial ciliated cells: 230.7;Epididymal efferent duct ciliated cells: 401.7;Esophageal apical cells: 176.5;Fallopian tube ciliated cells: 319.8;Respiratory ciliated cells: 305.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 7 "neutrophil: 55.9" "Lineage enriched" "Detected in all" 10 "granulocytes: 55.9" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019539 Approved Approved "Golgi apparatus,Cytosol" NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 3: Choroid plexus - Cilium" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 107: Ciliated cells - Cilia assembly & function" 132 "Golgi apparatus" Cytosol "HPA019539: " "unprognostic (3.45e-1)" "unprognostic (1.08e-1)" "unprognostic (8.77e-2)" "unprognostic (6.52e-2)" "unprognostic (1.90e-1)" "unprognostic (1.33e-1)" "potential prognostic unfavorable (1.16e-4)" "unprognostic (1.28e-3)" "unprognostic (1.45e-2)" "unprognostic (1.10e-1)" "potential prognostic favorable (1.97e-7)" "unprognostic (3.76e-3)" "unprognostic (6.33e-2)" "unprognostic (1.28e-1)" "unprognostic (1.68e-1)" "unprognostic (1.32e-1)" "unprognostic (1.21e-1)" "unprognostic (9.66e-2)" "unprognostic (3.73e-3)" "unprognostic (1.33e-2)" "unprognostic (2.91e-2)" "unprognostic (2.01e-2)" "unprognostic (8.89e-2)" "unprognostic (2.85e-2)" "unprognostic (1.00e-1)" "unprognostic (7.55e-2)" "unprognostic (9.77e-2)" "unprognostic (3.56e-2)" "unprognostic (2.71e-1)" "unprognostic (1.67e-2)" "unprognostic (1.75e-2)" FAM174B "LOC400451, MGC102891" ENSG00000185442 "Family with sequence similarity 174 member B" Q3ZCQ3 15 92617448-92809884 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 75.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 217.2;Neutrophils: 219.3;Transitional alveolar cells: 175.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 8.9" "Group enriched" "Detected in many" 7 "dendritic cells: 3.5;granulocytes: 2.9;T-cells: 8.9" "Cancer enhanced" "Detected in many" "prostate cancer: 66.4" "Breast - Breast glandular cells, Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Spleen - Macrophages, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015306 Approved Approved "Intermediate filaments" No No "Cluster 13: Non-specific - Mitochondria" "Cluster 60: Stomach - Digestion" "Cluster 24: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 24: Neutrophils - Innate immunity signal integration" "Intermediate filaments" "HPA015306: " "unprognostic (3.10e-2)" "potential prognostic unfavorable (1.90e-4)" "unprognostic (9.18e-2)" "unprognostic (3.22e-1)" "unprognostic (9.08e-2)" "unprognostic (6.65e-2)" "unprognostic (1.47e-1)" "unprognostic (5.15e-2)" "unprognostic (1.46e-1)" "unprognostic (1.19e-1)" "potential prognostic favorable (7.34e-4)" "unprognostic (5.89e-2)" "unprognostic (6.66e-2)" "unprognostic (1.12e-1)" "unprognostic (1.41e-2)" "potential prognostic favorable (7.37e-4)" "unprognostic (4.40e-1)" "unprognostic (1.44e-2)" "unprognostic (4.25e-1)" "unprognostic (7.61e-2)" "unprognostic (2.35e-1)" "unprognostic (1.13e-1)" "unprognostic (8.65e-2)" "unprognostic (5.47e-2)" "unprognostic (3.23e-2)" "unprognostic (4.61e-2)" "unprognostic (8.66e-3)" "unprognostic (7.31e-2)" "unprognostic (3.13e-1)" "unprognostic (2.02e-2)" "unprognostic (3.73e-3)" FAM174C "C19orf24, FLJ20640" ENSG00000228300 "Family with sequence similarity 174 member C" Q9BVV8 19 1275530-1279244 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal suprabasal cells: 204.0;Late spermatids: 574.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043279, HPA047026" Uncertain Approved "Nuclear speckles,Golgi apparatus" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 70: Non-specific - Protein processing" "Cluster 18: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" "Nuclear speckles" "Golgi apparatus" "HPA043279: , HPA047026: " "unprognostic (1.67e-1)" "unprognostic (2.25e-1)" "unprognostic (1.49e-1)" "unprognostic (4.22e-2)" "unprognostic (1.04e-1)" "unprognostic (2.49e-1)" "unprognostic (1.73e-1)" "unprognostic (1.89e-1)" "unprognostic (2.00e-2)" "unprognostic (2.52e-2)" "unprognostic (2.43e-3)" "unprognostic (4.60e-2)" "unprognostic (3.11e-3)" "unprognostic (1.28e-1)" "unprognostic (8.03e-2)" "unprognostic (7.99e-3)" "unprognostic (2.86e-1)" "unprognostic (1.30e-1)" "unprognostic (6.07e-2)" "unprognostic (1.52e-2)" "unprognostic (1.64e-1)" "unprognostic (7.14e-3)" "unprognostic (3.04e-1)" "unprognostic (2.82e-1)" "unprognostic (2.04e-1)" "unprognostic (3.08e-3)" "unprognostic (1.30e-1)" "unprognostic (4.70e-1)" "unprognostic (2.49e-1)" FAM177A1 C14orf24 ENSG00000151327 "Family with sequence similarity 177 member A1" Q8N128 14 35045117-35116630 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 729.4;Late primary spermatocytes: 634.9;Late spermatids: 704.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 1, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053222, HPA055440" Uncertain Approved Nucleoplasm,Vesicles "Secreted to blood" "No annotated function" NA NA 110000 "Cluster 35: Neutrophils - Protein binding" "Cluster 67: Testis - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 4 Vesicles Nucleoplasm "HPA053222: , HPA055440: " "unprognostic (2.64e-2)" "unprognostic (3.31e-2)" "unprognostic (1.01e-2)" "unprognostic (1.32e-2)" "unprognostic (1.14e-1)" "unprognostic (1.60e-1)" "unprognostic (4.92e-2)" "unprognostic (8.59e-2)" "unprognostic (3.82e-3)" "unprognostic (6.99e-2)" "potential prognostic favorable (4.27e-6)" "unprognostic (1.76e-2)" "unprognostic (9.59e-2)" "unprognostic (1.57e-3)" "unprognostic (6.65e-2)" "unprognostic (1.27e-1)" "unprognostic (6.69e-2)" "unprognostic (1.46e-1)" "unprognostic (1.09e-1)" "unprognostic (2.69e-2)" "unprognostic (2.90e-1)" "unprognostic (1.10e-2)" "unprognostic (3.65e-1)" "unprognostic (3.93e-2)" "unprognostic (1.71e-1)" "unprognostic (3.12e-2)" "unprognostic (2.25e-1)" "unprognostic (3.72e-1)" "unprognostic (4.12e-1)" "unprognostic (4.29e-2)" "unprognostic (3.61e-2)" FAM177B "FLJ43505, RP11-452F19.2" ENSG00000197520 "Family with sequence similarity 177 member B" A6PVY3 1 222737202-222751004 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "stomach 1: 42.6" "Cell type enhanced" "Detected in many" "B-cells: 80.0;Epididymal basal cells: 53.2;Fallopian secretory cells: 52.0;Foveolar cells: 266.6;Goblet cells: 257.5;Microglia: 187.5;monocytes: 52.4" "Cell type enriched" "Detected in some" 138 "central nervous system macrophage: 225.9" "Cancer enhanced" "Detected in many" "Pancreatic Adenocarcinoma (TCGA): 8.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 19 "memory B-cell: 40.0;naive B-cell: 50.3" "Lineage enriched" "Detected in many" 21 "B-cells: 50.3" "Cancer enhanced" "Detected in some" "lymphoma: 2.0;prostate cancer: 1.2" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Macrophages, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" HPA063059 Uncertain Approved "Mid piece" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 60: Stomach - Digestion" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 70: Intestinal goblet cells - Mucin production" "Mid piece" "HPA063059: " "unprognostic (1.32e-1)" "unprognostic (8.02e-2)" "unprognostic (1.27e-2)" "unprognostic (5.60e-2)" "unprognostic (1.00e-1)" "unprognostic (4.96e-2)" "unprognostic (3.02e-2)" "unprognostic (2.29e-1)" "unprognostic (2.57e-1)" "unprognostic (3.82e-2)" "unprognostic (6.57e-2)" "potential prognostic unfavorable (3.70e-5)" "unprognostic (1.60e-1)" FAM178B LOC51252 ENSG00000168754 "Family with sequence similarity 178 member B" Q8IXR5 2 96875882-96986580 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 17.8;brain: 15.9;epididymis: 5.2;lymphoid tissue: 11.4;testis: 7.8" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 71.6;Epididymal principal cells: 115.2;Erythrocyte progenitors: 396.7;Megakaryocyte-Erythroid progenitors: 50.1;Melanocytes: 42.2;Oligodendrocytes: 36.9;Undifferentiated spermatogonia: 75.0" "Cell type enhanced" "Detected in many" "oligodendrocyte: 42.6" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 18.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 7.0;skin cancer: 10.5" "Prostate - Smooth muscle cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Stomach - Fibroblasts" "Not detected" "Not detected" "Region enhanced" "Detected in some" "spinal cord: 3.8" "HPA042516, HPA062110" Uncertain Approved "Nuclear speckles,Golgi apparatus" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 47: Leukemia - Hemostasis" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" "Nuclear speckles" "Golgi apparatus" "HPA042516: , HPA062110: " "unprognostic (8.75e-3)" "unprognostic (2.54e-3)" "unprognostic (5.72e-1)" "unprognostic (3.35e-2)" "unprognostic (9.38e-2)" "unprognostic (1.67e-2)" "unprognostic (4.86e-2)" "potential prognostic favorable (1.93e-4)" "unprognostic (2.52e-1)" "potential prognostic unfavorable (1.96e-4)" "unprognostic (3.20e-2)" "unprognostic (5.14e-2)" "unprognostic (7.56e-2)" "unprognostic (1.72e-1)" "unprognostic (4.67e-2)" "unprognostic (9.67e-2)" "unprognostic (4.93e-2)" "unprognostic (1.56e-2)" FAM180A "HWKM1940, UNQ1940" ENSG00000189320 "Family with sequence similarity 180 member A" Q6UWF9 7 135728348-135748813 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 35.4;gallbladder: 15.0;heart muscle: 14.9" "Group enriched" "Detected in some" 7 "Fibroblasts: 40.1;Hepatic stellate cells: 142.0;Podocytes: 126.5" "Cell type enriched" "Detected in some" 15 "fibroblast: 28.1" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in many" 6 "choroid plexus: 9.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 8.8;Sarcoma: 21.6" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Colon - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021224, HPA062966" Uncertain Approved Vesicles "Secreted - unknown location" "No annotated function" NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" Vesicles "HPA021224: , HPA062966: " "unprognostic (3.35e-2)" "unprognostic (1.43e-1)" "unprognostic (1.16e-1)" "unprognostic (3.52e-1)" "unprognostic (6.86e-3)" "unprognostic (3.15e-2)" "potential prognostic favorable (1.34e-4)" "unprognostic (7.15e-2)" "unprognostic (4.38e-1)" "potential prognostic unfavorable (2.15e-4)" "unprognostic (3.64e-3)" "unprognostic (4.05e-1)" "potential prognostic favorable (2.69e-4)" "unprognostic (9.61e-3)" FAM180B LOC399888 ENSG00000196666 "Family with sequence similarity 180 member B" Q6P0A1 11 47586678-47589194 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "choroid plexus: 25.6" "Cell type enhanced" "Detected in some" "Astrocytes: 1.3;Bergmann glia: 1.2;Microglia: 3.6" "Cell type enhanced" "Detected in some" "astrocyte: 3.0;Bergmann glia: 4.5;central nervous system macrophage: 3.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Fibroblasts, Minor Salivary Gland - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblasts_1, Skin - Fibroblasts_2, Thyroid gland - Fibroblasts" "Region enhanced" "Detected in many" "spinal cord: 7.7" HPA029408 Uncertain "Secreted in other tissues" "No annotated function" NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 15: Non-specific - Transcription" "Cluster 6: Leukemia - Signal transduction" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 1 "HPA029408: " "unprognostic (1.68e-2)" "unprognostic (1.41e-1)" FAM181A C14orf152 ENSG00000140067 "Family with sequence similarity 181 member A" Q8N9Y4 14 93918894-93929608 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 13.9;testis: 32.1" "Group enriched" "Detected in some" 16 "Astrocytes: 10.1;Bergmann glia: 13.4;Ependymal cells: 20.5" "Group enriched" "Detected in some" 7 "astrocyte: 11.6;Bergmann glia: 20.6;ependymal cell: 27.7" "Group enriched" "Detected in some" 6 "Glioblastoma Multiforme (TCGA): 12.2;Ovary Serous Cystadenocarcinoma (TCGA): 5.1;Uterine Corpus Endometrial Carcinoma (TCGA): 3.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pituitary gland - Undifferentiated cells (Pituitary gland), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "basal ganglia: 42.1" "HPA001603, HPA018522" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 67: Testis - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 34: Ciliated cells - Cilia assembly & function" Nucleoplasm Cytosol "HPA001603: , HPA018522: " "unprognostic (1.34e-2)" "unprognostic (1.56e-2)" "unprognostic (6.02e-2)" "unprognostic (1.00e-1)" "unprognostic (5.88e-2)" "unprognostic (4.95e-2)" FAM181B "LOC220382, MGC33846" ENSG00000182103 "Family with sequence similarity 181 member B" A6NEQ2 11 82729940-82733864 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "brain: 19.9" "Cell type enhanced" "Detected in some" "Astrocytes: 83.6;Bergmann glia: 322.7;Endometrial ciliated cells: 23.9;Ependymal cells: 65.6;Epididymal efferent duct ciliated cells: 31.5;Oligodendrocyte progenitor cells: 56.4;Oligodendrocytes: 29.0;Schwann cells: 36.0" "Cell type enriched" "Detected in many" 4 "Bergmann glia: 422.0" "Cancer enriched" "Detected in some" 20 "Glioblastoma Multiforme (TCGA): 46.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "head and neck cancer: 2.7" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Stomach - Fibroblasts, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066861 Enhanced Approved "Nuclear membrane,Mitochondria" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 28: Astrocytes - Homeostasis & neuron support" Mitochondria "Nuclear membrane" "HPA066861: " "unprognostic (3.95e-2)" "unprognostic (9.95e-2)" "unprognostic (3.89e-2)" "unprognostic (2.95e-2)" "unprognostic (3.16e-2)" "unprognostic (1.15e-2)" "unprognostic (3.11e-2)" "unprognostic (2.63e-1)" "unprognostic (1.43e-1)" "unprognostic (1.28e-1)" FAM183A "hCG23177, LOC440585" ENSG00000186973 "Family with sequence similarity 183 member A" A6NL82 1 43145153-43156396 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "choroid plexus: 61.2;fallopian tube: 109.8" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 542.6;Ependymal cells: 183.5;Epididymal efferent duct ciliated cells: 1049.3;Fallopian tube ciliated cells: 1288.0;Late spermatids: 298.6;Respiratory ciliated cells: 951.3" "Cell type enriched" "Detected in some" 8 "ependymal cell: 245.6" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 18.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA043382, HPA049120" Approved Approved "Mid piece" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 107: Ciliated cells - Cilia assembly & function" "Mid piece" "HPA043382: , HPA049120: " "potential prognostic unfavorable (7.29e-5)" "unprognostic (4.01e-1)" "unprognostic (9.71e-2)" "unprognostic (1.94e-1)" "unprognostic (8.28e-2)" "unprognostic (7.58e-3)" "unprognostic (5.56e-2)" "unprognostic (7.42e-2)" "unprognostic (9.57e-2)" "unprognostic (1.10e-1)" "potential prognostic unfavorable (2.60e-6)" "unprognostic (6.63e-2)" "unprognostic (9.86e-2)" "unprognostic (1.90e-1)" "unprognostic (1.54e-1)" "unprognostic (2.00e-1)" "unprognostic (1.52e-3)" "unprognostic (4.37e-1)" "unprognostic (1.89e-1)" "unprognostic (3.69e-1)" FAM184A "C6orf60, FLJ13942" ENSG00000111879 "Family with sequence similarity 184 member A" Q8NB25 6 118959763-119149387 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 255.6;Astrocytes: 327.2;Bergmann glia: 334.5;Corticotrophs: 292.7;Cytotrophoblasts: 228.5;Ependymal cells: 471.1;Pituicytes/FSCs: 305.2;Pituitary stem cells: 228.7;Respiratory ciliated cells: 225.1;Salivary myoepithelial cells: 263.9;Syncytiotrophoblasts: 794.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 12.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 8.9" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034571 Uncertain Supported "Vesicles,Centriolar satellite,Basal body,Cytosol" NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 11: Neuronal - Sensory perception" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 16 "Centriolar satellite, Basal body, Cytosol" Vesicles "HPA034571: " "unprognostic (5.29e-2)" "unprognostic (1.05e-1)" "unprognostic (3.72e-2)" "unprognostic (2.03e-2)" "unprognostic (1.64e-1)" "unprognostic (2.16e-1)" "unprognostic (1.35e-1)" "unprognostic (2.23e-1)" "unprognostic (2.25e-1)" "unprognostic (2.99e-2)" "unprognostic (4.08e-2)" "unprognostic (3.04e-2)" "unprognostic (2.11e-1)" "unprognostic (2.84e-3)" "unprognostic (1.50e-2)" "unprognostic (8.01e-2)" "unprognostic (1.12e-1)" "unprognostic (6.97e-2)" "unprognostic (1.09e-2)" "potential prognostic favorable (4.20e-4)" "unprognostic (4.26e-1)" "unprognostic (3.91e-2)" "unprognostic (7.86e-2)" "unprognostic (1.85e-1)" "unprognostic (7.82e-3)" "unprognostic (1.34e-1)" "unprognostic (1.02e-2)" FAM184B KIAA1276 ENSG00000047662 "Family with sequence similarity 184 member B" Q9ULE4 4 17629306-17781621 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.8;retina: 1.6;skeletal muscle: 3.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 72.1;Epicardial cells: 93.2;Müller glia: 86.8;Myonuclei: 109.5;Oligodendrocyte progenitor cells: 99.0;Oocytes: 165.8;Renal collecting duct intercalated cells: 174.4;Retinal bipolar cells: 82.9;Thymic myoid cells: 88.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Kidney Chromophobe (TCGA): 4.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044119, HPA048458" Enhanced NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 1 "HPA044119: , HPA048458: " "unprognostic (7.31e-2)" "unprognostic (2.94e-1)" "unprognostic (4.72e-2)" "unprognostic (6.22e-2)" "unprognostic (3.57e-2)" "unprognostic (7.05e-2)" "unprognostic (1.36e-1)" "potential prognostic unfavorable (6.60e-4)" "unprognostic (2.95e-1)" FAM185A MGC35361 ENSG00000222011 "Family with sequence similarity 185 member A" Q8N0U4 7 102748971-102809225 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Epicardial cells: 252.4;Myonuclei: 108.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020470, HPA029883" Uncertain Approved Cytosol NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 76: Non-specific - Metabolism" "Cluster 31: Non-specific - Transcription" "Cluster 39: Non-specific - Transcription" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 1 Cytosol "HPA020470: , HPA029883: " "unprognostic (1.91e-1)" "unprognostic (4.72e-2)" "unprognostic (1.42e-1)" "unprognostic (5.60e-2)" "unprognostic (9.41e-2)" "potential prognostic favorable (9.40e-4)" "unprognostic (6.73e-2)" "unprognostic (2.28e-1)" "unprognostic (1.63e-2)" "unprognostic (1.46e-1)" "unprognostic (2.47e-1)" "unprognostic (9.69e-2)" "unprognostic (5.89e-2)" "unprognostic (5.18e-2)" FAM186A LOC121006 ENSG00000185958 "Family with sequence similarity 186 member A" A6NE01 12 50326230-50396622 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "testis: 14.2" "Group enriched" "Detected in many" 8 "Early spermatids: 602.3;Late primary spermatocytes: 187.8" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047128, HPA064735" Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 9: Non-specific - Receptor signaling" "Cluster 35: RS4;11 - Unknown function" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" "Nucleoplasm, Vesicles" "Plasma membrane" "HPA047128: , HPA064735: " "unprognostic (4.54e-2)" "unprognostic (1.73e-2)" FAM186B "C12orf25, DKFZP434J0113" ENSG00000135436 "Family with sequence similarity 186 member B" Q8IYM0 12 49582885-49605639 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 29 "testis: 44.3" "Group enriched" "Detected in many" 4 "Cardiomyocytes: 100.3;Early spermatids: 76.7;Late primary spermatocytes: 111.2;Late spermatids: 148.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039736, HPA040028" Uncertain Approved "Nucleoplasm,Centrosome,Basal body,Cytosol" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 56: Non-specific - Sensory perception" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 1 "Nucleoplasm, Cytosol" "Centrosome, Basal body" "HPA039736: , HPA040028: " "unprognostic (2.58e-1)" "unprognostic (4.35e-2)" "unprognostic (2.65e-1)" "unprognostic (1.38e-3)" "unprognostic (1.22e-1)" "unprognostic (4.61e-3)" "unprognostic (2.09e-1)" FAM187A ENSG00000214447 "Family with sequence similarity 187 member A" A6NFU0 17 44899774-44905390 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 4.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA056723 Approved Acrosome NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 21: Lymphoma - Adaptive immune response" Acrosome "HPA056723: " "unprognostic (1.33e-2)" "unprognostic (1.06e-1)" "unprognostic (1.70e-2)" "unprognostic (1.44e-1)" "unprognostic (1.07e-1)" "unprognostic (2.29e-1)" "unprognostic (4.55e-1)" "potential prognostic favorable (4.85e-5)" "unprognostic (1.30e-1)" "unprognostic (4.34e-2)" "unprognostic (8.28e-2)" "unprognostic (3.40e-3)" "unprognostic (6.83e-3)" "unprognostic (8.49e-2)" "unprognostic (8.45e-2)" "unprognostic (2.69e-1)" "unprognostic (2.64e-1)" "unprognostic (1.23e-3)" "unprognostic (2.49e-2)" "unprognostic (1.24e-1)" "unprognostic (1.94e-1)" "unprognostic (4.40e-2)" "unprognostic (2.03e-1)" "unprognostic (2.71e-2)" FAM187B "FLJ25660, TMEM162" ENSG00000177558 "Family with sequence similarity 187 member B" Q17R55 19 35224800-35228739 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 238 "testis: 65.2" "Cell type enriched" "Detected in some" 5 "Late spermatids: 3917.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA079535 Enhanced NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 1 "HPA079535: " FAM193A "C4orf8, RES4-22" ENSG00000125386 "Family with sequence similarity 193 member A" P78312 4 2536647-2732573 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043116 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 67: Testis - Mixed function" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 7: Non-specific - Transcription" 2 "Plasma membrane, Cytosol" "HPA043116: " "unprognostic (1.68e-1)" "unprognostic (2.95e-1)" "unprognostic (1.00e-1)" "unprognostic (1.64e-2)" "unprognostic (9.60e-2)" "unprognostic (2.73e-2)" "unprognostic (1.15e-1)" "unprognostic (1.12e-1)" "unprognostic (1.05e-2)" "unprognostic (1.19e-1)" "unprognostic (1.11e-2)" "potential prognostic favorable (3.82e-4)" "unprognostic (7.44e-2)" "unprognostic (5.82e-3)" "unprognostic (1.40e-1)" "unprognostic (1.98e-1)" "unprognostic (1.02e-1)" "unprognostic (2.35e-1)" "unprognostic (1.25e-1)" "unprognostic (2.52e-1)" "unprognostic (2.17e-2)" "unprognostic (1.14e-2)" "unprognostic (6.12e-3)" "unprognostic (6.06e-3)" "unprognostic (1.43e-2)" "unprognostic (1.12e-1)" "unprognostic (2.40e-1)" "unprognostic (1.07e-1)" "unprognostic (2.44e-1)" "unprognostic (4.00e-2)" "unprognostic (1.11e-1)" FAM193B "FLJ10404, IRIZIO, KIAA1931" ENSG00000146067 "Family with sequence similarity 193 member B" Q96PV7 5 177519789-177554586 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035847, HPA035848" Approved Enhanced Nucleoplasm,Nucleoli NA NA "Cluster 64: Non-specific - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 56: Non-specific - Sensory perception" "Cluster 7: Non-specific - Transcription" 6 "Nucleoplasm, Nucleoli" "HPA035847: , HPA035848: " "unprognostic (8.09e-2)" "unprognostic (3.37e-2)" "unprognostic (1.66e-1)" "unprognostic (4.54e-1)" "unprognostic (5.80e-2)" "unprognostic (2.53e-1)" "unprognostic (3.93e-2)" "unprognostic (9.62e-2)" "potential prognostic favorable (9.24e-5)" "unprognostic (1.55e-2)" "potential prognostic unfavorable (8.95e-6)" "unprognostic (1.11e-2)" "unprognostic (4.88e-2)" "unprognostic (3.66e-2)" "unprognostic (1.32e-1)" "unprognostic (2.41e-2)" "unprognostic (3.35e-1)" "unprognostic (3.50e-1)" "unprognostic (3.55e-2)" "unprognostic (2.39e-1)" "unprognostic (6.71e-3)" "unprognostic (5.34e-3)" "potential prognostic unfavorable (2.38e-4)" "unprognostic (3.76e-2)" "unprognostic (5.50e-2)" "unprognostic (3.40e-1)" "unprognostic (1.88e-1)" "unprognostic (5.74e-2)" "unprognostic (2.17e-1)" "unprognostic (3.19e-1)" "unprognostic (4.06e-2)" FAM199X CXorf39 ENSG00000123575 "Family with sequence similarity 199, X-linked" Q6PEV8 X 104166453-104195902 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003093 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 22: Epididymis - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 89: Adipocytes - Lipid metabolism" 5 "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA003093: " "unprognostic (1.35e-1)" "unprognostic (5.86e-3)" "unprognostic (1.85e-1)" "unprognostic (1.93e-1)" "unprognostic (5.96e-2)" "unprognostic (8.76e-2)" "unprognostic (5.68e-2)" "unprognostic (2.26e-1)" "unprognostic (2.64e-1)" "unprognostic (1.22e-2)" "unprognostic (1.00e-2)" "unprognostic (1.72e-2)" "unprognostic (2.62e-1)" "unprognostic (8.09e-2)" "unprognostic (4.95e-3)" "unprognostic (2.49e-1)" "unprognostic (8.00e-3)" "unprognostic (1.07e-1)" "unprognostic (3.10e-1)" "unprognostic (1.78e-1)" "potential prognostic unfavorable (5.38e-4)" "unprognostic (1.42e-1)" "unprognostic (4.68e-2)" "unprognostic (7.73e-2)" "unprognostic (4.31e-2)" "unprognostic (1.78e-1)" "unprognostic (2.21e-1)" "unprognostic (1.04e-1)" "unprognostic (1.78e-1)" "unprognostic (6.27e-2)" "unprognostic (1.12e-1)" FAM200A "C7orf38, DKFZp727G131, FLJ36794" ENSG00000221909 "Family with sequence similarity 200 member A" Q8TCP9 7 99546300-99558536 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 104.8;Late primary spermatocytes: 62.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017855 Uncertain NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 39: Non-specific - Transcription" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 1 "HPA017855: " "unprognostic (8.95e-3)" "unprognostic (7.61e-2)" "unprognostic (2.61e-3)" "potential prognostic unfavorable (1.38e-4)" "unprognostic (6.08e-2)" "unprognostic (6.69e-2)" "potential prognostic unfavorable (2.73e-5)" "unprognostic (5.48e-2)" "unprognostic (1.51e-1)" "unprognostic (3.99e-3)" "potential prognostic favorable (2.41e-5)" "unprognostic (6.86e-3)" "unprognostic (3.40e-2)" "potential prognostic unfavorable (6.83e-5)" "unprognostic (4.46e-2)" "unprognostic (6.93e-2)" "unprognostic (7.59e-2)" "unprognostic (2.50e-2)" "potential prognostic favorable (9.17e-4)" "unprognostic (3.66e-1)" "unprognostic (2.93e-2)" "unprognostic (7.97e-2)" "unprognostic (1.12e-1)" "unprognostic (2.10e-1)" "unprognostic (3.76e-2)" "unprognostic (8.54e-3)" "unprognostic (7.04e-2)" "unprognostic (2.13e-1)" "unprognostic (2.48e-2)" "unprognostic (5.26e-2)" "unprognostic (3.06e-2)" FAM200B C4orf53 ENSG00000237765 "Family with sequence similarity 200 member B" P0CF97 4 15681662-15690447 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 34.1;Brain inhibitory neurons: 35.9;Early spermatids: 68.6;Late primary spermatocytes: 73.1;Late spermatids: 110.0;Neutrophils: 29.4;Oligodendrocytes: 51.5;Other brain neurons: 39.1;Podocytes: 36.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 15.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA017855 Uncertain NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 31: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 98: Neurons - Neurotransmission & signaling" "HPA017855: " "unprognostic (1.98e-1)" "unprognostic (8.60e-3)" "unprognostic (3.14e-3)" "unprognostic (1.46e-1)" "unprognostic (2.31e-1)" "unprognostic (1.95e-1)" "unprognostic (1.57e-1)" "unprognostic (2.35e-3)" "unprognostic (1.21e-1)" "unprognostic (3.53e-3)" "unprognostic (1.19e-3)" "potential prognostic favorable (5.93e-5)" "potential prognostic favorable (1.43e-4)" "unprognostic (3.95e-2)" "unprognostic (1.89e-1)" "unprognostic (4.41e-1)" "unprognostic (8.99e-3)" "potential prognostic favorable (2.17e-4)" "unprognostic (5.61e-3)" "unprognostic (1.05e-2)" "unprognostic (2.54e-1)" "unprognostic (8.95e-3)" "unprognostic (6.71e-2)" "unprognostic (2.36e-1)" "unprognostic (7.63e-3)" "unprognostic (1.39e-2)" "unprognostic (1.22e-1)" "unprognostic (4.58e-2)" "unprognostic (5.12e-2)" "unprognostic (1.21e-2)" "unprognostic (1.23e-1)" FAM204A "bA319I23.1, C10orf84, FLJ13188" ENSG00000165669 "Family with sequence similarity 204 member A" Q9H8W3 10 118297925-118342328 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 344.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038182, HPA062025" Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 14: Neurons - Synaptic function" "Cluster 52: Non-specific - Mitochondria" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 6 "Nucleoplasm, Nucleoli" "HPA038182: , HPA062025: " "unprognostic (4.52e-2)" "unprognostic (2.00e-1)" "unprognostic (1.53e-1)" "unprognostic (5.33e-3)" "unprognostic (1.01e-1)" "unprognostic (4.12e-2)" "unprognostic (8.85e-3)" "unprognostic (5.38e-3)" "unprognostic (4.45e-3)" "potential prognostic favorable (5.34e-8)" "unprognostic (1.87e-1)" "unprognostic (2.27e-1)" "unprognostic (2.75e-2)" "unprognostic (7.37e-2)" "unprognostic (1.74e-1)" "unprognostic (5.59e-2)" "unprognostic (4.71e-1)" "unprognostic (5.69e-2)" "unprognostic (1.24e-1)" "unprognostic (1.71e-3)" "unprognostic (3.21e-2)" "unprognostic (6.01e-3)" "unprognostic (4.64e-2)" "unprognostic (5.04e-2)" "unprognostic (1.13e-1)" "unprognostic (9.58e-2)" "unprognostic (1.15e-1)" "unprognostic (2.18e-1)" "unprognostic (6.33e-3)" "unprognostic (1.42e-2)" FAM205A C9orf144B ENSG00000205108 "Family with sequence similarity 205 member A" Q6ZU69 9 34723053-34729488 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 233 "testis: 23.3" "Group enriched" "Detected in some" 5 "Early spermatids: 170.8;Late primary spermatocytes: 52.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" HPA071267 Enhanced Approved "Nucleoli fibrillar center,Plasma membrane,Acrosome,Mid piece,Principal piece" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 23: Choroid plexus - Mixed function" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" "Plasma membrane, Acrosome" "Nucleoli fibrillar center, Mid piece, Principal piece" "HPA071267: " FAM205C FAM205CP ENSG00000187791 "Family with sequence similarity 205 member C" A6NFA0 9 34889066-34895764 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 39 "testis: 28.2" "Group enriched" "Detected in some" 12 "Early spermatids: 386.3;Late spermatids: 634.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Testis - Late spermatids" "Low region specificity" "Detected in many" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 51: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" FAM209A "C20orf106, dJ1153D9.3" ENSG00000124103 "Family with sequence similarity 209 member A" Q5JX71 20 56517187-56526152 "Predicted membrane proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "testis: 150.9" "Cell type enriched" "Detected in many" 4 "Early spermatids: 2793.0" "Low cell type specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Testis - Early spermatids, Testis - Late spermatids" HPA079442 Uncertain "Plasma membrane,Cell Junctions" NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 57: Testis - Spermatogenesis" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 200 "Plasma membrane, Cell Junctions" "HPA079442: " FAM209B "C20orf107, dJ1153D9.4" ENSG00000213714 "Family with sequence similarity 209 member B" Q5JX69 20 56533246-56536520 "Predicted membrane proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "testis: 108.0" "Group enriched" "Detected in some" 5 "Early spermatids: 2103.6;Late primary spermatocytes: 552.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in single" "eosinophil: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in single" "Testis - Early spermatids, Testis - Late spermatids" HPA042144 Enhanced NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 31: Non-specific - Transcription" "Cluster 20: Myeloma - Immune response" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" "HPA042144: " FAM20A DKFZp434F2322 ENSG00000108950 "FAM20A golgi associated secretory pathway pseudokinase" Q96MK3 17 68535113-68601367 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Biomineralization "Amelogenesis imperfecta, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 23.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 212.3;Epicardial cells: 218.3;Fibro-adipogenic progenitors: 158.6;Hepatocytes: 155.5;Hofbauer cells: 486.4;Kupffer cells: 184.5;Lacrimal acinar cells: 207.4;Late spermatids: 311.4;Macrophages: 152.3;monocytes: 187.1;Renal collecting duct principal cells: 318.1;Salivary acinar cells: 217.7;Sertoli cells: 171.5;Transitional alveolar cells: 193.0" "Group enriched" "Detected in all" 5 "fibroblast: 205.2;thalamic excitatory: 67.9;vascular associated smooth muscle cell: 61.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "testis cancer: 2.0" "Adipose subcutaneous - Adipose progenitor cells, Colon - Endothelial cells, Heart muscle - Macrophages, Kidney - Macrophages, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048964 Approved "Secreted in other tissues" Other NA NA 4100000 "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 38: Sub-cortical - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 1 "HPA048964: " "unprognostic (1.65e-1)" "unprognostic (2.21e-2)" "unprognostic (4.38e-2)" "unprognostic (7.16e-2)" "unprognostic (1.80e-1)" "unprognostic (4.45e-2)" "unprognostic (6.99e-2)" "unprognostic (8.23e-2)" "potential prognostic unfavorable (3.56e-7)" "unprognostic (7.26e-2)" "unprognostic (2.61e-1)" "unprognostic (3.63e-3)" "potential prognostic favorable (3.42e-4)" "unprognostic (9.80e-3)" "unprognostic (5.62e-3)" "unprognostic (2.52e-3)" "unprognostic (1.72e-1)" "unprognostic (1.64e-1)" "unprognostic (1.28e-1)" "unprognostic (1.62e-2)" "potential prognostic unfavorable (3.75e-4)" "unprognostic (8.60e-2)" "unprognostic (1.37e-1)" "unprognostic (7.87e-3)" "unprognostic (5.32e-2)" "unprognostic (1.45e-1)" "unprognostic (8.26e-2)" FAM20B "GXK1, KIAA0475" ENSG00000116199 "FAM20B glycosaminoglycan xylosylkinase" O75063 1 179025804-179076567 "Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007409 Approved Supported "Nucleoplasm,Golgi apparatus" NA NA 340000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 75: Ovary - Mixed function" "Cluster 14: Neurons - Synaptic function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 21 "Golgi apparatus" Nucleoplasm "HPA007409: " "unprognostic (1.28e-2)" "unprognostic (8.12e-2)" "unprognostic (1.21e-1)" "unprognostic (1.33e-1)" "unprognostic (5.25e-2)" "unprognostic (2.77e-2)" "unprognostic (9.90e-2)" "unprognostic (7.53e-2)" "unprognostic (2.45e-1)" "unprognostic (7.76e-3)" "potential prognostic favorable (2.39e-4)" "unprognostic (2.61e-2)" "unprognostic (1.76e-2)" "unprognostic (7.02e-2)" "unprognostic (8.41e-2)" "unprognostic (1.38e-2)" "unprognostic (1.06e-2)" "unprognostic (2.35e-1)" "unprognostic (2.75e-2)" "unprognostic (1.70e-1)" "unprognostic (2.80e-2)" "unprognostic (3.06e-2)" "unprognostic (3.35e-2)" "unprognostic (1.57e-1)" "unprognostic (1.32e-2)" "unprognostic (1.97e-1)" "unprognostic (1.17e-1)" "unprognostic (9.88e-2)" "unprognostic (1.59e-1)" "unprognostic (2.77e-2)" "unprognostic (2.09e-1)" FAM20C "DKFZp547D065, DMP4, G-CK, IMAGE:4942737" ENSG00000177706 "FAM20C golgi associated secretory pathway kinase" Q8IXL6 7 192571-260772 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" Biomineralization "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 35.9;Oligodendrocytes: 25.5;Papillary tip epithelial cells: 41.9;Podocytes: 99.9;Proximal tubule cells: 212.9;Renal collecting duct intercalated cells: 42.5;Renal collecting duct principal cells: 140.2;Renal connecting tubule cells: 88.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 50.0" "Minor Salivary Gland - Minor salivary glandular cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019823 Supported "Nucleoplasm,Golgi apparatus" "Secreted in other tissues" Enzyme NA NA 49000000 "Cluster 74: Non-specific - Signal transduction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 88: Proximal tubular cells - Transmembrane transport" 5 "Golgi apparatus" Nucleoplasm "HPA019823: " "unprognostic (1.31e-1)" "unprognostic (4.50e-2)" "unprognostic (2.09e-1)" "potential prognostic unfavorable (1.09e-4)" "unprognostic (3.00e-2)" "unprognostic (8.39e-2)" "unprognostic (2.31e-3)" "unprognostic (2.50e-2)" "unprognostic (8.29e-2)" "potential prognostic favorable (8.81e-6)" "potential prognostic favorable (1.27e-4)" "unprognostic (1.87e-2)" "unprognostic (1.38e-1)" "unprognostic (1.83e-1)" "unprognostic (4.95e-2)" "unprognostic (1.10e-2)" "unprognostic (4.03e-2)" "unprognostic (2.90e-2)" "unprognostic (3.58e-1)" "potential prognostic unfavorable (3.19e-4)" "unprognostic (1.90e-3)" "unprognostic (9.29e-2)" "unprognostic (3.31e-1)" "unprognostic (2.64e-1)" "unprognostic (3.62e-1)" "unprognostic (1.35e-2)" "unprognostic (3.46e-1)" "unprognostic (4.15e-3)" "unprognostic (9.69e-2)" "unprognostic (1.45e-1)" "unprognostic (2.60e-2)" FAM210A "C18orf19, HsT2329, MGC24180" ENSG00000177150 "Family with sequence similarity 210 member A" Q96ND0 18 13663347-13726663 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 30.9" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 171.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014324, HPA051564" Uncertain Approved "Nucleoplasm,Golgi apparatus,Mitochondria" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 21: Non-specific - Metabolism" "Cluster 69: Skin cancer - ECM organization" "Cluster 75: Non-specific - Chaperones and protein folding" 11 "Nucleoplasm, Golgi apparatus, Mitochondria" "HPA014324: , HPA051564: " "unprognostic (1.35e-2)" "unprognostic (1.46e-1)" "unprognostic (3.18e-2)" "unprognostic (1.66e-1)" "unprognostic (7.35e-2)" "unprognostic (8.63e-2)" "unprognostic (2.26e-2)" "unprognostic (3.98e-2)" "unprognostic (8.11e-3)" "validated prognostic favorable (6.47e-7)" "validated prognostic favorable (7.63e-5)" "unprognostic (2.86e-2)" "unprognostic (1.92e-2)" "unprognostic (8.45e-3)" "unprognostic (2.21e-2)" "unprognostic (4.66e-2)" "unprognostic (2.06e-1)" "unprognostic (4.96e-2)" "unprognostic (3.09e-2)" "unprognostic (4.84e-3)" "potential prognostic unfavorable (3.39e-4)" "unprognostic (1.09e-2)" "unprognostic (1.76e-1)" "unprognostic (2.78e-1)" "unprognostic (2.21e-1)" "unprognostic (2.12e-2)" "unprognostic (3.53e-1)" "unprognostic (3.22e-1)" "unprognostic (7.81e-2)" FAM210B "C20orf108, dJ1167H4.1, DKFZP434A1114" ENSG00000124098 "Family with sequence similarity 210 member B" Q96KR6 20 56358974-56368663 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Erythrocyte maturation" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 250.7;Erythrocytes: 276.4;Hepatocytes: 176.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042652 Approved Approved "Plasma membrane,Cytosol" No No "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 76: Non-specific - Metabolism" "Cluster 38: Sub-cortical - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 58 "Plasma membrane, Cytosol" "HPA042652: " "unprognostic (8.26e-2)" "unprognostic (1.62e-1)" "unprognostic (4.53e-2)" "unprognostic (2.54e-1)" "unprognostic (1.01e-1)" "unprognostic (1.12e-1)" "unprognostic (3.37e-2)" "unprognostic (5.77e-2)" "unprognostic (4.34e-2)" "potential prognostic favorable (7.61e-6)" "unprognostic (3.94e-2)" "unprognostic (3.96e-2)" "unprognostic (2.06e-1)" "potential prognostic favorable (7.15e-4)" "unprognostic (1.50e-1)" "unprognostic (1.43e-1)" "unprognostic (1.04e-1)" "unprognostic (1.98e-1)" "unprognostic (1.46e-1)" "unprognostic (2.51e-1)" "unprognostic (1.02e-1)" "unprognostic (2.13e-1)" "unprognostic (2.20e-2)" "unprognostic (4.99e-3)" "unprognostic (7.73e-2)" "unprognostic (1.14e-1)" "unprognostic (6.07e-2)" "unprognostic (9.22e-2)" "unprognostic (1.03e-3)" FAM216A "C12orf24, HSU79274" ENSG00000204856 "Family with sequence similarity 216 member A" Q8WUB2 12 110468415-110490385 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "brain: 30.4;testis: 55.5" "Group enriched" "Detected in many" 4 "Early primary spermatocytes: 153.6;Late primary spermatocytes: 286.5;Late spermatids: 78.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038286 Enhanced Approved "Actin filaments" NA NA "Cluster 18: Non-specific - Translation" "Cluster 39: Testis - Nuclear processes" "Cluster 1: Neurons - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 1 "Actin filaments" "HPA038286: " "unprognostic (3.36e-2)" "unprognostic (3.57e-2)" "unprognostic (6.13e-2)" "unprognostic (5.59e-2)" "unprognostic (2.14e-1)" "unprognostic (2.49e-1)" "potential prognostic favorable (1.28e-5)" "unprognostic (1.45e-2)" "unprognostic (1.97e-2)" "unprognostic (4.74e-3)" "unprognostic (1.03e-1)" "unprognostic (4.37e-3)" "potential prognostic unfavorable (2.39e-4)" "unprognostic (1.76e-2)" "potential prognostic unfavorable (5.93e-4)" "unprognostic (5.16e-2)" "unprognostic (1.82e-1)" "unprognostic (5.48e-2)" "unprognostic (1.21e-1)" "unprognostic (2.17e-2)" "unprognostic (2.42e-2)" "unprognostic (9.79e-3)" "unprognostic (8.61e-2)" "unprognostic (1.78e-1)" "unprognostic (4.29e-1)" "unprognostic (3.80e-2)" "unprognostic (1.44e-1)" "unprognostic (2.10e-3)" "unprognostic (4.49e-2)" FAM216B "C13orf30, FLJ40919" ENSG00000179813 "Family with sequence similarity 216 member B" Q8N7L0 13 42781550-42791549 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "fallopian tube: 73.0" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 190.2;Ependymal cells: 81.7;Epididymal efferent duct ciliated cells: 167.0;Fallopian tube ciliated cells: 270.8;Respiratory ciliated cells: 408.6" "Cell type enriched" "Detected in some" 15 "ependymal cell: 111.8" "Cancer enhanced" "Detected in some" "Lung Adenocarcinoma (TCGA): 2.8;Uterine Corpus Endometrial Carcinoma (TCGA): 4.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 8 "skin cancer: 1.6" "Lung - Respiratory ciliated cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA040118 Uncertain NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 66: Non-specific - Mitochondria" "Cluster 107: Ciliated cells - Cilia assembly & function" "HPA040118: " "unprognostic (1.49e-1)" "unprognostic (1.58e-2)" "unprognostic (9.83e-2)" "unprognostic (2.63e-1)" "unprognostic (1.78e-2)" "unprognostic (1.07e-1)" FAM217A "C6orf146, MGC43581" ENSG00000145975 "Family with sequence similarity 217 member A" Q8IXS0 6 4049434-4087344 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "testis: 13.9" "Group enriched" "Detected in many" 4 "Cardiomyocytes: 217.6;Early spermatids: 213.9;Epicardial cells: 195.6;Late primary spermatocytes: 205.9;Late spermatids: 703.6" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Ascending Loop of Henle cells, Pituitary gland - Somatotropes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" HPA035455 Uncertain NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 11: Neuronal - Sensory perception" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 1 "HPA035455: " FAM217B "C20orf177, dJ551D2.5" ENSG00000196227 "Family with sequence similarity 217 member B" Q9NTX9 20 59933764-59948680 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophil progenitors: 109.4;Neutrophils: 108.0;Tuft cells: 80.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pituitary gland - Somatotropes, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041021, HPA056698" Approved Enhanced Nucleoplasm NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 34: Non-specific - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 19 Nucleoplasm "HPA041021: , HPA056698: " "unprognostic (1.74e-1)" "unprognostic (5.00e-2)" "unprognostic (8.60e-2)" "unprognostic (1.91e-2)" "unprognostic (7.47e-2)" "unprognostic (1.82e-1)" "unprognostic (2.05e-1)" "unprognostic (8.92e-2)" "unprognostic (6.48e-3)" "potential prognostic favorable (8.36e-4)" "unprognostic (1.87e-1)" "unprognostic (3.62e-2)" "potential prognostic unfavorable (3.59e-5)" "unprognostic (3.12e-2)" "unprognostic (6.75e-2)" "unprognostic (2.90e-3)" "unprognostic (1.72e-2)" "unprognostic (3.10e-1)" "potential prognostic unfavorable (2.86e-6)" "unprognostic (3.42e-2)" "unprognostic (8.67e-3)" "unprognostic (5.95e-2)" "potential prognostic favorable (9.77e-4)" "unprognostic (2.37e-2)" "unprognostic (3.19e-2)" "unprognostic (2.53e-1)" "unprognostic (1.70e-1)" "unprognostic (2.57e-1)" "unprognostic (2.50e-1)" FAM219A "bA573M23.5, C9orf25, FLJ39031" ENSG00000164970 "Family with sequence similarity 219 member A" Q8IW50 9 34398184-34458570 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 73.6" "Cell type enhanced" "Detected in many" "Myonuclei: 101.3;Retinal ganglion cells: 100.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019338, HPA052909" Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 45: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 4 "Golgi apparatus" "Nucleoplasm, Vesicles" "HPA019338: , HPA052909: " "unprognostic (8.85e-2)" "unprognostic (5.67e-3)" "unprognostic (1.03e-1)" "unprognostic (2.68e-2)" "unprognostic (1.67e-3)" "unprognostic (9.89e-2)" "unprognostic (4.54e-2)" "unprognostic (1.17e-1)" "unprognostic (1.65e-2)" "unprognostic (8.25e-2)" "unprognostic (6.78e-2)" "unprognostic (2.72e-2)" "potential prognostic unfavorable (1.04e-6)" "unprognostic (1.17e-2)" "unprognostic (1.99e-3)" "unprognostic (8.57e-2)" "unprognostic (1.78e-3)" "unprognostic (2.32e-1)" "unprognostic (1.11e-2)" "unprognostic (1.27e-3)" "unprognostic (4.79e-2)" "unprognostic (9.53e-2)" "unprognostic (9.47e-2)" "unprognostic (1.84e-3)" "unprognostic (9.61e-2)" "unprognostic (8.52e-2)" "unprognostic (2.75e-1)" "unprognostic (2.87e-2)" "unprognostic (2.81e-2)" FAM219B "C15orf17, FLJ00005" ENSG00000178761 "Family with sequence similarity 219 member B" Q5XKK7 15 74899992-74906883 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 225.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048929, HPA058064" Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 20: Pituitary gland - Hormone signaling" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 58: Non-specific - Nuclear processes" "Cluster 85: Squamous epithelial cells - Keratinization" 9 Nucleoplasm "Golgi apparatus" "HPA048929: , HPA058064: " "unprognostic (4.00e-3)" "unprognostic (9.09e-2)" "unprognostic (2.71e-1)" "unprognostic (1.03e-3)" "unprognostic (5.33e-2)" "unprognostic (3.58e-1)" "potential prognostic favorable (7.88e-4)" "unprognostic (1.89e-1)" "unprognostic (1.69e-1)" "validated prognostic favorable (5.95e-7)" "validated prognostic favorable (3.02e-4)" "potential prognostic favorable (1.42e-4)" "unprognostic (1.30e-2)" "unprognostic (1.15e-3)" "unprognostic (2.80e-1)" "unprognostic (4.13e-1)" "unprognostic (1.78e-2)" "unprognostic (2.12e-1)" "unprognostic (1.07e-1)" "unprognostic (1.39e-2)" "unprognostic (9.41e-2)" "unprognostic (3.31e-2)" "unprognostic (2.23e-1)" "unprognostic (1.75e-1)" "unprognostic (1.34e-1)" "unprognostic (1.11e-1)" "unprognostic (2.10e-1)" "unprognostic (1.15e-1)" "unprognostic (3.70e-1)" FAM220A "ACPIN1, C7orf70, MGC12966, SIPAR" ENSG00000178397 "Family with sequence similarity 220 member A" Q7Z4H9 7 6329411-6348981 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 65.9;testis: 72.9" "Cell type enhanced" "Detected in some" "Bergmann glia: 1.9;Brain excitatory neurons: 3.3;Brain inhibitory neurons: 3.3;Distal convoluted tubule cells: 5.5;Ependymal cells: 1.8;Loop of henle epithelial cells: 4.6;Microglia: 3.0;Oligodendrocyte progenitor cells: 2.3;Oligodendrocytes: 2.3;Other brain neurons: 3.4;Papillary tip epithelial cells: 3.6;Podocytes: 3.9;Proximal tubule cells: 3.9;Renal collecting duct intercalated cells: 5.1;Renal collecting duct principal cells: 3.1;Renal connecting tubule cells: 4.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" HPA055050 Approved Vesicles NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 67: Testis - Mixed function" "Cluster 34: Non-specific - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" 2 Vesicles "HPA055050: " "unprognostic (1.68e-2)" "unprognostic (2.38e-2)" "unprognostic (1.66e-1)" "unprognostic (1.85e-1)" "unprognostic (3.84e-2)" "unprognostic (1.58e-2)" "potential prognostic unfavorable (6.79e-4)" "unprognostic (8.05e-2)" "unprognostic (7.11e-2)" "potential prognostic favorable (3.31e-6)" "unprognostic (1.08e-1)" "unprognostic (2.04e-2)" "potential prognostic unfavorable (6.65e-6)" "unprognostic (2.51e-2)" "unprognostic (1.26e-2)" "unprognostic (2.47e-2)" "unprognostic (7.81e-2)" "unprognostic (7.37e-2)" "unprognostic (1.96e-3)" "unprognostic (6.28e-2)" "unprognostic (1.06e-1)" "unprognostic (6.12e-2)" "unprognostic (1.20e-2)" "unprognostic (5.02e-2)" "unprognostic (6.89e-2)" "unprognostic (7.61e-3)" "unprognostic (8.94e-3)" "potential prognostic unfavorable (3.94e-4)" "unprognostic (1.69e-1)" FAM221A "C7orf46, DKFZp686F0810, FLJ45875, MGC72075" ENSG00000188732 "Family with sequence similarity 221 member A" A4D161 7 23680130-23703249 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 30.1" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 88.8;Oligodendrocytes: 98.0;Retinal pigment epithelial cells: 251.5;Sertoli cells: 104.0" "Cell type enhanced" "Detected in all" "oligodendrocyte: 131.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA019719, HPA026748, HPA026752" Enhanced Approved Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" 11 Cytosol "HPA019719: , HPA026748: , HPA026752: " "unprognostic (2.42e-1)" "unprognostic (1.44e-1)" "unprognostic (7.42e-3)" "unprognostic (9.27e-3)" "unprognostic (3.99e-2)" "unprognostic (1.81e-2)" "unprognostic (2.16e-3)" "unprognostic (2.33e-1)" "unprognostic (2.00e-1)" "potential prognostic favorable (1.00e-4)" "unprognostic (3.25e-2)" "unprognostic (3.12e-2)" "potential prognostic unfavorable (7.68e-4)" "unprognostic (1.58e-3)" "unprognostic (1.69e-1)" "unprognostic (6.44e-2)" "unprognostic (2.12e-1)" "unprognostic (1.31e-1)" "unprognostic (6.60e-2)" "unprognostic (1.75e-1)" "unprognostic (2.24e-2)" "unprognostic (1.40e-1)" "unprognostic (8.73e-2)" "unprognostic (7.47e-3)" "unprognostic (1.61e-1)" "unprognostic (7.99e-2)" "unprognostic (2.56e-2)" "unprognostic (1.16e-1)" "unprognostic (1.44e-1)" FAM221B C9orf128 ENSG00000204930 "Family with sequence similarity 221 member B" A6H8Z2 9 35816391-35828747 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "bone marrow: 2.7;testis: 8.3" "Group enriched" "Detected in some" 59 "Early spermatids: 242.9;Late primary spermatocytes: 83.1;Late spermatids: 125.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney Chromophobe (TCGA): 5.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 2.8" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in single" "Adrenocortical cancer: 2.3" "Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA026577 Enhanced NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 25: Non-specific - Transcription" "Cluster 56: Non-specific - Sensory perception" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 13 "HPA026577: " "unprognostic (1.73e-1)" "unprognostic (1.77e-1)" "unprognostic (1.24e-1)" "unprognostic (1.27e-3)" "unprognostic (9.48e-2)" FAM222A "C12orf34, FLJ14721" ENSG00000139438 "Family with sequence similarity 222 member A" Q5U5X8 12 109713825-109770495 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 50.4" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 89.0;Early spermatids: 171.5;Late spermatids: 117.5;Oligodendrocytes: 106.7;Retinal horizontal cells: 140.2;Rod photoreceptor cells: 185.9;Somatotrophs: 81.2" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 63.0;oligodendrocyte: 141.0" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 23.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 7 "Neuroblastoma: 49.6" "Adrenal gland - Adrenal cortex cells, Kidney - Ascending Loop of Henle cells, Minor Salivary Gland - Minor salivary glandular cells, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040181, HPA075616" Uncertain Approved "Golgi apparatus,Cell Junctions,Midbody ring" Yes NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 6: Non-specific - Immune response" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 20: Non-specific - Transcription regulation" 1 "Golgi apparatus" "Cell Junctions, Midbody ring" "HPA040181: , HPA075616: " "unprognostic (7.81e-2)" "unprognostic (1.44e-2)" "unprognostic (2.00e-2)" "unprognostic (2.01e-1)" "unprognostic (3.77e-3)" "unprognostic (1.85e-1)" "potential prognostic favorable (4.95e-4)" "unprognostic (4.47e-2)" "unprognostic (6.14e-2)" "unprognostic (1.62e-1)" "unprognostic (2.44e-2)" "unprognostic (4.18e-2)" "unprognostic (3.34e-2)" "unprognostic (9.27e-3)" "unprognostic (7.28e-2)" "unprognostic (3.61e-1)" "unprognostic (3.35e-3)" "unprognostic (7.29e-2)" "unprognostic (1.18e-1)" "potential prognostic favorable (1.06e-4)" "unprognostic (7.20e-2)" "unprognostic (1.41e-1)" "unprognostic (7.39e-2)" "unprognostic (8.08e-2)" "unprognostic (4.84e-2)" "unprognostic (1.97e-3)" "unprognostic (8.34e-2)" "unprognostic (1.81e-1)" "unprognostic (5.56e-2)" FAM222B "C17orf63, FLJ10700" ENSG00000173065 "Family with sequence similarity 222 member B" Q8WU58 17 28755980-28855232 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051840, HPA062239" Approved Enhanced Nucleoplasm NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 67: Testis - Mixed function" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Breast cancer - Unknown function" "Cluster 58: Mast cells - Allergic inflammatory responses" 28 Nucleoplasm "HPA051840: , HPA062239: " "unprognostic (2.84e-2)" "unprognostic (6.19e-2)" "potential prognostic unfavorable (7.65e-4)" "unprognostic (1.56e-1)" "unprognostic (9.48e-2)" "unprognostic (1.80e-1)" "unprognostic (3.73e-1)" "unprognostic (2.33e-2)" "unprognostic (8.41e-3)" "unprognostic (1.25e-3)" "unprognostic (6.46e-2)" "unprognostic (8.86e-2)" "potential prognostic unfavorable (2.66e-5)" "potential prognostic unfavorable (5.46e-4)" "unprognostic (2.52e-1)" "unprognostic (6.27e-3)" "unprognostic (4.62e-2)" "unprognostic (1.23e-2)" "unprognostic (1.94e-2)" "unprognostic (1.36e-2)" "unprognostic (6.33e-3)" "unprognostic (3.73e-1)" "unprognostic (5.45e-2)" "unprognostic (2.52e-1)" "unprognostic (5.13e-2)" "unprognostic (1.22e-1)" "unprognostic (2.52e-1)" "unprognostic (3.67e-2)" "unprognostic (2.18e-1)" FAM227A ENSG00000184949 "Family with sequence similarity 227 member A" F5H4B4 22 38578118-38656629 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 4.7;testis: 4.7" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 207.7;Early spermatids: 144.3;Endometrial ciliated cells: 175.8;Ependymal cells: 303.9;Epididymal efferent duct ciliated cells: 88.6;Fallopian tube ciliated cells: 136.5;Lactotrophs: 81.3;Late spermatids: 88.1;Respiratory ciliated cells: 363.7;Respiratory deuterosomal cells: 79.8" "Group enriched" "Detected in many" 4 "choroid plexus epithelial cell: 162.7;ependymal cell: 321.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Skin - Outer root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA003077 Uncertain Uncertain Nucleoplasm NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 34: Ciliated cells - Cilia assembly & function" 1 Nucleoplasm "HPA003077: " "unprognostic (5.46e-2)" "unprognostic (2.15e-1)" "unprognostic (1.82e-2)" "unprognostic (8.95e-2)" "unprognostic (1.52e-1)" "unprognostic (1.77e-2)" "unprognostic (2.84e-3)" "unprognostic (1.45e-2)" "unprognostic (1.40e-1)" "unprognostic (6.22e-2)" FAM227B "C15orf33, FLJ32800" ENSG00000166262 "Family with sequence similarity 227 member B" Q96M60 15 49326962-49620929 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 614.6;Epicardial cells: 413.9;Fibro-adipogenic progenitors: 352.7;Myonuclei: 192.3;Oocytes: 225.6" "Cell type enhanced" "Detected in all" "ependymal cell: 167.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA049774, HPA061695" Uncertain Approved "Nuclear speckles" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 46: Brainstem - Mixed function" "Cluster 20: Myeloma - Immune response" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "Nuclear speckles" "HPA049774: , HPA061695: " "unprognostic (8.64e-2)" "unprognostic (2.51e-1)" "unprognostic (7.36e-3)" "unprognostic (7.92e-2)" "unprognostic (2.64e-2)" "unprognostic (3.29e-1)" "unprognostic (2.53e-1)" "unprognostic (1.98e-2)" "unprognostic (6.30e-2)" "validated prognostic favorable (6.12e-9)" "validated prognostic favorable (1.28e-7)" "potential prognostic favorable (3.77e-4)" "potential prognostic favorable (8.63e-4)" "unprognostic (2.82e-1)" "unprognostic (1.73e-1)" "unprognostic (3.08e-1)" "unprognostic (1.89e-1)" "unprognostic (6.09e-2)" "unprognostic (5.06e-2)" "unprognostic (1.27e-2)" "unprognostic (1.02e-1)" "unprognostic (6.56e-2)" "unprognostic (1.82e-1)" "unprognostic (1.04e-1)" "unprognostic (1.93e-1)" "unprognostic (2.04e-1)" "unprognostic (1.99e-1)" "unprognostic (9.62e-2)" "unprognostic (3.82e-2)" FAM228A "C2orf84, FLJ30851" ENSG00000186453 "Family with sequence similarity 228 member A" Q86W67 2 24175053-24200849 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "testis: 33.8" "Cell type enhanced" "Detected in some" "Early primary spermatocytes: 52.7;Early spermatids: 66.7;Late primary spermatocytes: 249.2;Late spermatids: 15.6;Oocytes: 69.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Adipocytes (Breast), Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA075817 Approved Nucleoplasm NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 9: Non-specific - Receptor signaling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 16 Nucleoplasm "HPA075817: " "potential prognostic favorable (8.93e-4)" "unprognostic (9.28e-3)" "unprognostic (1.35e-1)" FAM228B ENSG00000219626 "Family with sequence similarity 228 member B" P0C875 2 24076526-24169640 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 137.8;Late spermatids: 129.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052598, HPA063357" Uncertain Approved "Golgi apparatus" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "Golgi apparatus" "HPA052598: , HPA063357: " "unprognostic (4.28e-2)" "unprognostic (9.30e-2)" "unprognostic (1.41e-1)" "unprognostic (1.86e-2)" "unprognostic (1.19e-1)" "unprognostic (1.79e-2)" "unprognostic (2.26e-1)" "unprognostic (1.40e-1)" "unprognostic (5.72e-2)" "potential prognostic unfavorable (2.31e-5)" "unprognostic (5.23e-3)" "unprognostic (8.92e-2)" "unprognostic (9.96e-3)" "unprognostic (5.02e-2)" "unprognostic (2.29e-1)" "unprognostic (1.52e-1)" "unprognostic (5.73e-2)" "unprognostic (3.05e-1)" "unprognostic (1.71e-1)" "unprognostic (1.86e-3)" "unprognostic (5.37e-3)" "unprognostic (2.49e-2)" "unprognostic (9.36e-2)" "unprognostic (5.16e-2)" "unprognostic (1.81e-2)" "potential prognostic unfavorable (2.59e-4)" "unprognostic (2.11e-1)" "unprognostic (8.30e-2)" "unprognostic (1.09e-2)" FAM229A ENSG00000225828 "Family with sequence similarity 229 member A" H3BQW9 1 32361270-32364278 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in many" 9 "testis: 86.7" "Cell type enhanced" "Detected in many" "Early spermatids: 3595.3;Late primary spermatocytes: 1138.7;Late spermatids: 5145.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Late spermatids" "Not detected" "Not detected" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 15: Non-specific - Transcription" "Cluster 35: RS4;11 - Unknown function" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" "unprognostic (2.86e-1)" "unprognostic (9.51e-2)" "unprognostic (1.72e-2)" "unprognostic (6.28e-2)" "potential prognostic favorable (4.17e-4)" "unprognostic (3.31e-1)" "unprognostic (2.61e-1)" "unprognostic (1.18e-1)" "unprognostic (3.72e-2)" "unprognostic (1.28e-1)" "unprognostic (1.01e-1)" "unprognostic (2.13e-2)" "unprognostic (1.21e-3)" "unprognostic (1.78e-1)" "unprognostic (2.15e-1)" "unprognostic (4.00e-2)" "unprognostic (3.75e-2)" "unprognostic (6.99e-2)" "unprognostic (6.47e-2)" "unprognostic (5.04e-3)" "unprognostic (7.34e-2)" FAM229B "C6orf225, DKFZp586F0922, LOC619208" ENSG00000203778 "Family with sequence similarity 229 member B" Q4G0N7 6 112087591-112102790 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "testis: 427.8" "Cell type enhanced" "Detected in many" "Early spermatids: 3604.4;Late primary spermatocytes: 2623.1;Late spermatids: 10748.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 96.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA036068 Approved "Nucleoplasm,Nucleoli,Golgi apparatus" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 21: Non-specific - Metabolism" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 4 Nucleoplasm "Nucleoli, Golgi apparatus" "HPA036068: " "unprognostic (6.55e-2)" "unprognostic (1.72e-1)" "unprognostic (3.46e-1)" "unprognostic (3.04e-2)" "unprognostic (1.55e-1)" "unprognostic (7.36e-2)" "unprognostic (2.07e-1)" "unprognostic (1.54e-2)" "unprognostic (1.44e-2)" "unprognostic (2.03e-1)" "unprognostic (7.07e-2)" "unprognostic (3.62e-3)" "unprognostic (1.32e-2)" "unprognostic (9.31e-3)" "unprognostic (4.03e-2)" "unprognostic (5.39e-2)" "unprognostic (1.81e-1)" "unprognostic (1.18e-1)" "unprognostic (1.57e-1)" "potential prognostic favorable (2.61e-4)" "unprognostic (2.70e-1)" "unprognostic (8.20e-2)" "unprognostic (2.42e-1)" "unprognostic (4.35e-1)" "unprognostic (1.90e-1)" "potential prognostic unfavorable (9.88e-4)" "unprognostic (1.97e-1)" "unprognostic (8.16e-2)" "unprognostic (2.10e-2)" FAM234A "C16orf9, DKFZP761D0211, FLJ32603, ITFG3" ENSG00000167930 "Family with sequence similarity 234 member A" Q9H0X4 16 234521-272183 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 154.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011651, HPA071871" Uncertain Approved Nucleoplasm,Mitochondria NA NA 1600000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 54: Non-specific - Transcription" "Cluster 1: Enterocytes - Absorption and Digestion" 23 Mitochondria Nucleoplasm "HPA011651: , HPA071871: " "unprognostic (6.52e-2)" "unprognostic (1.68e-2)" "unprognostic (2.98e-2)" "unprognostic (4.65e-3)" "unprognostic (1.84e-1)" "unprognostic (1.03e-1)" "unprognostic (2.98e-1)" "unprognostic (1.79e-1)" "unprognostic (1.59e-2)" "unprognostic (3.14e-1)" "unprognostic (7.50e-3)" "unprognostic (5.44e-2)" "unprognostic (7.00e-3)" "unprognostic (3.59e-2)" "unprognostic (6.25e-2)" "unprognostic (1.06e-1)" "unprognostic (6.83e-2)" "unprognostic (4.75e-2)" "unprognostic (2.28e-1)" "unprognostic (5.93e-2)" "unprognostic (4.23e-1)" "unprognostic (1.63e-1)" "unprognostic (3.20e-2)" "unprognostic (7.60e-2)" "unprognostic (2.24e-1)" "unprognostic (1.12e-1)" "unprognostic (1.18e-1)" "unprognostic (2.51e-2)" "unprognostic (3.08e-1)" FAM234B KIAA1467 ENSG00000084444 "Family with sequence similarity 234 member B" A2RU67 12 13044381-13142521 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 21.7" "Cell type enhanced" "Detected in many" "Breast lactating cells: 53.1;Early spermatids: 102.6;Late spermatids: 40.8;Retinal bipolar cells: 45.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Breast Invasive Carcinoma (TCGA): 33.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Skin - Keratinocyte (other), Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010803, HPA010850" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 14 "Endoplasmic reticulum" "HPA010803: , HPA010850: " "unprognostic (1.73e-2)" "potential prognostic unfavorable (2.88e-4)" "unprognostic (2.40e-2)" "unprognostic (5.32e-3)" "unprognostic (1.30e-1)" "unprognostic (2.43e-1)" "unprognostic (1.98e-2)" "unprognostic (4.02e-3)" "unprognostic (2.68e-1)" "potential prognostic favorable (2.30e-4)" "unprognostic (2.61e-3)" "unprognostic (3.27e-1)" "unprognostic (3.37e-2)" "unprognostic (1.37e-2)" "unprognostic (5.56e-3)" "unprognostic (4.35e-2)" "unprognostic (1.31e-1)" "unprognostic (4.09e-3)" "unprognostic (2.26e-1)" "unprognostic (5.62e-2)" "potential prognostic unfavorable (1.60e-4)" "unprognostic (7.03e-2)" "unprognostic (1.81e-1)" "unprognostic (4.77e-1)" "unprognostic (3.89e-1)" "unprognostic (6.24e-2)" "unprognostic (2.49e-1)" "unprognostic (4.61e-3)" "unprognostic (7.46e-2)" FAM236A "DMRTC1-AS1, LINC00684" ENSG00000275520 "Family with sequence similarity 235 member A" A0A1B0GUQ0 X 72938163-72938958 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 78 "testis: 144.8" "Cell type enhanced" "Detected in some" "Early spermatids: 4.4;Late primary spermatocytes: 5.2;Late spermatids: 15.4;Sertoli cells: 24.5" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "Testicular Germ Cell Tumor (TCGA): 3.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 29: Forebrain - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" "unprognostic (2.62e-1)" FAM236B ENSG00000268994 "Family with sequence similarity 236 member B" A0A1B0GV22 X 72781865-72782660 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 78 "testis: 96.8" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 59: Leukemia - T-cell receptor" FAM236C ENSG00000283594 "Family with sequence similarity 236 member C" P0DP71 X 72912615-72913401 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 18 "testis: 2.3" "Cell type enriched" "Detected in single" 11 "Sertoli cells: 9.8" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" FAM236D ENSG00000225396 "Family with sequence similarity 236 member D" A0A1B0GTK5 X 72807425-72808210 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 18 "testis: 2.3" "Cell type enriched" "Detected in single" 9 "Sertoli cells: 6.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" FAM237A ENSG00000235118 "Family with sequence similarity 237 member A" A0A1B0GTK4 2 206642487-206649365 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 4 "brain: 1.8" "Group enriched" "Detected in some" 4 "Early spermatids: 5.2;Late primary spermatocytes: 8.3;Late spermatids: 3.8;Other brain neurons: 2.4" "Cell type enhanced" "Detected in some" "medium spiny neuron: 3.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Pituitary gland - Thyrotropes, Testis - Early spermatids, Testis - Late spermatids" "Region enhanced" "Detected in single" "hypothalamus: 1.7" "Region enhanced" "Detected in single" "basal ganglia: 1.4" "Intracellular and membrane" "No annotated function" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 109: Neurons - Neuronal signaling" FAM237B ENSG00000283267 "Family with sequence similarity 237 member B" A0A1B0GVD1 7 90316503-90321304 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Epicardial cells: 34.1;Müller glia: 14.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Group enriched" "Detected in some" 6 "hypothalamus: 1.6;thalamus: 4.9" "Low region specificity" "Detected in all" "Secreted in other tissues" "No annotated function" NA NA "Cluster 17: Choroid plexus - Cilium" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" FAM240A ENSG00000283473 "Family with sequence similarity 240 member A" A0A1B0GVK7 3 46612525-46626543 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 5 "Breast lactating cells: 24.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA "Cluster 53: Neurons - Mixed function" "Cluster 4: Breast lactating luminal cells - Lactation" FAM240B ENSG00000283329 "Family with sequence similarity 240 member B" A0A1B0GVZ2 9 38694266-38720133 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Epicardial cells: 2.3;Thymic myoid cells: 6.8;Undifferentiated spermatogonia: 3.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 4.2" "Lineage enriched" "Detected in single" 6 "granulocytes: 4.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 34: Non-specific - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 46: Skeletal myocytes - Muscle structure & formation" "unprognostic (4.64e-1)" "unprognostic (2.65e-1)" "unprognostic (3.26e-1)" FAM240C ENSG00000216921 "Family with sequence similarity 240 member C" A0A1B0GVR7 2 241893988-241902551 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "tongue: 209.9" "Cell type enhanced" "Detected in some" "Astrocytes: 2.2;Granulosa cells: 1.6;Late spermatids: 8.4;Myosatellite cells: 9.5;Pancreatic acinar cells: 1.9;Parietal cells: 1.8;Thymic myoid cells: 6.8" "Cell type enhanced" "Detected in some" "fibroblast: 2.4;lower rhombic lip: 3.0" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 8.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" HPA073342 Approved Nucleoplasm NA NA "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 19: Astrocytes - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" Nucleoplasm "HPA073342: " "unprognostic (3.26e-2)" "unprognostic (1.76e-2)" "unprognostic (3.71e-2)" "unprognostic (3.55e-1)" "unprognostic (1.84e-1)" "unprognostic (1.78e-2)" "unprognostic (1.70e-1)" FAM241A "C4orf32, FLJ39370" ENSG00000174749 "Family with sequence similarity 241 member A" Q8N8J7 4 112145454-112195256 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 175.6;Breast lactating cells: 237.0;Thymocytes: 159.2;Vascular endothelial cells: 253.5" "Cell type enhanced" "Detected in many" "hippocampal CA4: 155.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Pancreas - Endothelial cells, Spleen - Endothelial cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062443, HPA069294" Approved Enhanced "Golgi apparatus" No No "Cluster 20: Non-specific - DNA binding" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 9: Non-specific - Receptor signaling" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 32 "Golgi apparatus" "HPA062443: , HPA069294: " "unprognostic (1.37e-1)" "unprognostic (4.19e-2)" "potential prognostic unfavorable (1.34e-4)" "unprognostic (1.19e-2)" "unprognostic (2.68e-2)" "unprognostic (3.39e-2)" "unprognostic (4.78e-3)" "unprognostic (2.07e-2)" "unprognostic (3.49e-3)" "unprognostic (3.90e-2)" "potential prognostic favorable (6.78e-4)" "unprognostic (7.83e-2)" "unprognostic (6.58e-3)" "unprognostic (1.43e-1)" "unprognostic (3.40e-1)" "unprognostic (1.19e-1)" "unprognostic (5.69e-2)" "unprognostic (4.68e-2)" "unprognostic (5.15e-2)" "unprognostic (6.98e-2)" "unprognostic (8.88e-3)" "unprognostic (7.54e-3)" "unprognostic (2.35e-2)" "unprognostic (5.34e-3)" "unprognostic (2.98e-1)" "unprognostic (9.31e-3)" "unprognostic (2.79e-1)" "unprognostic (1.48e-2)" "unprognostic (1.43e-2)" FAM241B C10orf35 ENSG00000171224 "Family with sequence similarity 241 member B" Q96D05 10 69630247-69633596 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 73.4" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 31.0;Early primary spermatocytes: 31.4;Early spermatids: 117.8;Late spermatids: 28.7;Oocytes: 46.1;Other brain neurons: 28.9;Retinal pigment epithelial cells: 29.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 13 "gdT-cell: 4.3;MAIT T-cell: 10.9;memory CD4 T-cell: 10.6;memory CD8 T-cell: 7.0;naive CD4 T-cell: 17.2;naive CD8 T-cell: 5.8;T-reg: 7.8" "Lineage enriched" "Detected in single" 25 "T-cells: 17.2" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Skin - Outer root sheath cells, Spleen - T-cells, Testis - Late spermatids" "Low region specificity" "Detected in all" HPA034591 Enhanced Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 11: T-cells - Unknown function" "Cluster 27: Cerebellum - Synaptic function" "Cluster 29: Forebrain - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 33 "Nucleoplasm, Centrosome" Cytosol "HPA034591: " "unprognostic (7.37e-2)" "unprognostic (1.31e-1)" "unprognostic (6.01e-2)" "unprognostic (4.79e-2)" "unprognostic (6.52e-2)" "unprognostic (2.10e-3)" "unprognostic (1.14e-2)" "potential prognostic unfavorable (6.28e-4)" "unprognostic (3.29e-2)" "unprognostic (4.09e-2)" "unprognostic (3.75e-3)" "unprognostic (1.35e-2)" "potential prognostic unfavorable (2.34e-4)" "unprognostic (1.08e-1)" "unprognostic (2.29e-1)" "unprognostic (6.25e-2)" "unprognostic (3.21e-1)" "unprognostic (1.70e-1)" "unprognostic (3.40e-2)" "unprognostic (2.89e-2)" "unprognostic (1.70e-2)" "unprognostic (5.74e-2)" "unprognostic (5.97e-3)" "unprognostic (9.86e-2)" "unprognostic (3.61e-3)" "unprognostic (3.45e-2)" "unprognostic (2.93e-1)" "unprognostic (1.02e-1)" "unprognostic (2.11e-1)" FAM246A ENSG00000286102 "Family with sequence similarity 246 member A" A0A494C0Y3 22 21360601-21361299 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 24: Neurons - Mixed function" FAM246B ENSG00000286175 "Family with sequence similarity 246 member B" A0A494C0N9 22 18633984-18634682 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA FAM246C ENSG00000286025 "Family with sequence similarity 246 member C (gene/pseudogene)" 22 19029524-19031242 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 1.6;liver: 1.0;retina: 1.1;testis: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Kidney - Proximal tubular cells, Testis - Early spermatids, Testis - Late spermatids" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" FAM24A AC073585.4 ENSG00000203795 "Family with sequence similarity 24 member A" A6NFZ4 10 122910610-122913111 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 166 "testis: 16.5" "Group enriched" "Detected in some" 20 "Early spermatids: 156.9;Late primary spermatocytes: 383.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" HPA052490 Supported "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 27: Breast cancer - Unknown function" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" "HPA052490: " FAM24B "AC073585.2, MGC45962" ENSG00000213185 "Family with sequence similarity 24 member B" Q8N5W8 10 122849078-122879641 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 15.1" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 8.7;Brain inhibitory neurons: 10.0;Epididymal clear cells: 12.2;Late primary spermatocytes: 26.9;Microglia: 10.0;Oligodendrocytes: 10.4;Other brain neurons: 8.5;Renal collecting duct intercalated cells: 26.8;Renal connecting tubule cells: 8.2;Respiratory ionocytes: 45.7" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 4 "Kidney Chromophobe (TCGA): 31.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Intercalated cells, Pituitary gland - Somatotropes, Testis - Early spermatids" HPA052490 Supported "Intracellular and membrane" "No annotated function" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 72: Kidney - Transmembrane transport" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" 2 "HPA052490: " "unprognostic (3.80e-2)" "unprognostic (2.51e-2)" "unprognostic (4.43e-2)" "unprognostic (4.97e-3)" "unprognostic (4.32e-3)" "unprognostic (1.66e-1)" "unprognostic (2.36e-1)" "unprognostic (2.09e-1)" "unprognostic (5.40e-2)" "unprognostic (3.49e-2)" "potential prognostic unfavorable (1.09e-4)" "unprognostic (3.40e-1)" "unprognostic (3.41e-2)" "validated prognostic unfavorable (4.85e-6)" "validated prognostic unfavorable (4.60e-4)" "unprognostic (2.74e-1)" "unprognostic (1.61e-2)" "unprognostic (6.62e-2)" "unprognostic (5.59e-2)" "unprognostic (2.24e-1)" "unprognostic (2.36e-1)" "unprognostic (1.09e-1)" "unprognostic (1.54e-2)" "unprognostic (3.34e-2)" "unprognostic (9.52e-3)" "unprognostic (1.63e-1)" "unprognostic (9.96e-3)" "unprognostic (1.28e-1)" "unprognostic (1.36e-1)" "unprognostic (2.92e-1)" "unprognostic (3.15e-3)" FAM25A bA96C23.5 ENSG00000188100 "Family with sequence similarity 25 member A" B3EWG3 10 87020294-87024730 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 200.4;esophagus: 510.0;skin 1: 173.2;vagina: 179.4" "Cell type enriched" "Detected in some" 40 "Esophageal apical cells: 1430.7" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Head and Neck Squamous Cell Carcinoma (TCGA): 189.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 12.0;head and neck cancer: 9.1" "Skin - Keratinocyte (granular)" HPA044808 Uncertain NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 84: Apical squamous epithelium - Cornification" 16 "HPA044808: " "unprognostic (3.38e-2)" "unprognostic (4.44e-1)" "unprognostic (4.07e-1)" "unprognostic (5.21e-2)" "unprognostic (6.97e-2)" "unprognostic (1.20e-1)" "unprognostic (2.49e-2)" "potential prognostic unfavorable (1.88e-6)" "unprognostic (2.21e-1)" "unprognostic (3.08e-3)" "unprognostic (8.30e-1)" FAM25C bA164N7.4 ENSG00000276430 "Family with sequence similarity 25 member C" B3EWG5 10 47995322-47999791 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "cervix: 11.6;esophagus: 21.2;salivary gland: 9.5;skin 1: 37.6;vagina: 10.1" "Cell type enhanced" "Detected in single" "Papillary tip epithelial cells: 1.1" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Head and Neck Squamous Cell Carcinoma (TCGA): 26.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 7.3;head and neck cancer: 2.9" HPA044808 Uncertain NA NA "Cluster 58: Skin - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" "HPA044808: " "unprognostic (5.47e-1)" "unprognostic (1.33e-1)" "unprognostic (2.49e-2)" "unprognostic (6.66e-1)" FAM25G bA301J7.4 ENSG00000189090 "Family with sequence similarity 25 member G" B3EWG6 10 47487219-47491700 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 7 "cervix: 11.6;esophagus: 20.8;salivary gland: 9.5;skin 1: 37.8;vagina: 9.8" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 2.7;Esophageal suprabasal cells: 1.6;Oocytes: 4.6;Suprabasal keratinocytes: 2.5;Undifferentiated spermatogonia: 5.1" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "Head and Neck Squamous Cell Carcinoma (TCGA): 2.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 7.3;head and neck cancer: 2.9" HPA044808 Uncertain NA NA "Cluster 58: Skin - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" "HPA044808: " "unprognostic (3.86e-1)" FAM32A "DKFZP586O0120, OTAG-12" ENSG00000105058 "Family with sequence similarity 32 member A" Q9Y421 19 16185380-16192046 "Essential proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 257.7;Platelets: 161.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051712 Approved Supported Nucleoplasm,Nucleoli NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 38: Sub-cortical - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 4 "Nucleoplasm, Nucleoli" "HPA051712: " "unprognostic (1.20e-1)" "unprognostic (5.11e-2)" "unprognostic (1.72e-1)" "unprognostic (5.23e-2)" "unprognostic (8.76e-2)" "unprognostic (7.01e-2)" "unprognostic (7.29e-2)" "unprognostic (1.87e-2)" "unprognostic (1.17e-1)" "unprognostic (8.07e-3)" "unprognostic (2.58e-3)" "unprognostic (2.33e-2)" "unprognostic (1.49e-1)" "validated prognostic unfavorable (2.41e-4)" "validated prognostic unfavorable (3.75e-4)" "unprognostic (1.72e-1)" "unprognostic (1.55e-2)" "unprognostic (5.13e-2)" "unprognostic (1.34e-3)" "unprognostic (4.08e-2)" "unprognostic (1.15e-1)" "unprognostic (1.53e-2)" "unprognostic (2.12e-1)" "unprognostic (2.37e-3)" "unprognostic (1.27e-1)" "unprognostic (3.39e-1)" "unprognostic (4.52e-2)" "unprognostic (3.00e-1)" "unprognostic (7.52e-2)" "unprognostic (7.93e-2)" "unprognostic (2.70e-2)" FAM3A "2-19, DXS560S, XAP-7" ENSG00000071889 "FAM3 metabolism regulating signaling molecule A" P98173 X 154506159-154516242 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 117.7;Esophageal apical cells: 131.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025016, HPA035268, HPA056991" Uncertain Approved "Nucleoplasm,Nucleoli rim,Mitotic chromosome" "Secreted to blood" "No annotated function" Yes No "Cluster 41: Basophils - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 30: White matter - Myelination" "Cluster 36: Non-specific - mRNA processing" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 2 "Nucleoli rim" "Nucleoplasm, Mitotic chromosome" "CAB025016: , HPA035268: , HPA056991: " "unprognostic (7.07e-2)" "unprognostic (4.38e-2)" "unprognostic (7.93e-3)" "unprognostic (2.08e-1)" "unprognostic (6.76e-3)" "unprognostic (2.14e-1)" "potential prognostic unfavorable (2.66e-4)" "unprognostic (1.83e-1)" "unprognostic (6.97e-3)" "unprognostic (6.64e-2)" "unprognostic (5.94e-2)" "unprognostic (8.98e-2)" "potential prognostic favorable (6.40e-4)" "unprognostic (4.15e-2)" "unprognostic (4.83e-2)" "unprognostic (2.57e-1)" "unprognostic (1.81e-1)" "unprognostic (4.37e-2)" "unprognostic (4.17e-1)" "unprognostic (9.28e-2)" "unprognostic (4.71e-3)" "unprognostic (3.89e-2)" "unprognostic (4.00e-1)" "unprognostic (2.01e-1)" "unprognostic (6.49e-2)" "unprognostic (5.42e-2)" "unprognostic (1.43e-1)" "unprognostic (1.29e-1)" "unprognostic (3.82e-1)" "unprognostic (2.43e-1)" "unprognostic (1.21e-1)" FAM3B "2-21, C21orf11, C21orf76, D21M16SJHU19e, ORF9, PANDER, PRED44" ENSG00000183844 "FAM3 metabolism regulating signaling molecule B" P58499 21 41304212-41357727 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Apoptosis Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 134.3;pancreas: 191.7;salivary gland: 112.4;stomach 1: 108.3" "Cell type enhanced" "Detected in many" "Breast lactating cells: 264.2;Cytotrophoblasts: 416.6;Enterocytes: 791.7;Esophageal apical cells: 809.1;Esophageal suprabasal cells: 306.1;Foveolar cells: 267.4;Gastric chief cells: 292.7;Pancreatic acinar cells: 456.9;Paneth cells: 278.5;Urothelial cells: 375.1" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 6.7;choroid plexus epithelial cell: 3.8" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 191.5" "Region enriched" "Detected in single" 9 "choroid plexus: 2.3" "Immune cell enhanced" "Detected in some" "eosinophil: 1.4;neutrophil: 2.8" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.8" "Cancer enhanced" "Detected in many" "breast cancer: 12.3;colorectal cancer: 8.6;lung cancer: 7.7" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells (progenitors), Liver - Cholangiocytes, Pituitary gland - Corticotropes, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015885, HPA029777, CAB034131" Enhanced Approved Vesicles "Secreted to blood" Cytokine NA NA 2080000 85000 "Cluster 60: Stomach - Digestion" "Cluster 36: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 1: Enterocytes - Absorption and Digestion" 7 Vesicles "CAB034131: , HPA015885: , HPA029777: " "potential prognostic favorable (6.29e-5)" "unprognostic (2.26e-1)" "unprognostic (1.26e-1)" "unprognostic (3.57e-3)" "unprognostic (1.46e-1)" "unprognostic (1.19e-1)" "unprognostic (3.86e-1)" "unprognostic (1.34e-2)" "unprognostic (1.56e-1)" "unprognostic (2.89e-2)" "unprognostic (1.35e-1)" "unprognostic (1.10e-1)" "unprognostic (2.56e-3)" "unprognostic (6.45e-2)" "unprognostic (1.42e-2)" "unprognostic (9.54e-2)" "unprognostic (3.90e-2)" "unprognostic (8.82e-2)" "unprognostic (3.25e-1)" "unprognostic (4.67e-1)" "unprognostic (5.97e-2)" "unprognostic (2.16e-1)" "unprognostic (1.70e-1)" "unprognostic (2.80e-1)" "unprognostic (1.86e-3)" "unprognostic (2.15e-1)" "unprognostic (1.91e-1)" "unprognostic (1.50e-1)" "unprognostic (7.73e-2)" FAM3C "GS3876, ILEI" ENSG00000196937 "FAM3 metabolism regulating signaling molecule C" Q92520 7 121348878-121396364 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Developmental protein" Oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 257.4;Parietal cells: 236.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "memory B-cell: 22.6;naive B-cell: 20.1" "Lineage enriched" "Detected in many" 7 "B-cells: 22.6" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043376, HPA050548" Enhanced Enhanced "Golgi apparatus" "Secreted in other tissues" "Developmental protein" NA NA 13000000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 77: Intestine - Digestion" "Cluster 14: Neurons - Synaptic function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 56 "Golgi apparatus" "HPA043376: , HPA050548: " "unprognostic (1.93e-2)" "unprognostic (2.18e-2)" "unprognostic (2.03e-1)" "unprognostic (2.05e-2)" "unprognostic (9.97e-2)" "unprognostic (7.68e-2)" "unprognostic (5.60e-3)" "unprognostic (1.88e-3)" "unprognostic (3.22e-3)" "unprognostic (6.16e-3)" "potential prognostic favorable (2.06e-5)" "unprognostic (1.88e-2)" "potential prognostic unfavorable (4.91e-4)" "unprognostic (4.56e-3)" "unprognostic (8.14e-2)" "unprognostic (1.36e-2)" "potential prognostic unfavorable (5.66e-5)" "unprognostic (4.18e-2)" "unprognostic (2.27e-1)" "unprognostic (8.03e-3)" "unprognostic (6.75e-3)" "unprognostic (7.32e-3)" "unprognostic (5.36e-3)" "unprognostic (1.76e-1)" "unprognostic (1.70e-1)" "unprognostic (1.09e-1)" "unprognostic (1.48e-1)" "unprognostic (1.14e-2)" "unprognostic (1.07e-1)" "unprognostic (2.67e-1)" "unprognostic (3.24e-2)" FAM3D "EF7, OIT1" ENSG00000198643 "FAM3 metabolism regulating signaling molecule D" Q96BQ1 3 58633946-58666834 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 270.0;intestine: 458.5;salivary gland: 440.9" "Cell type enriched" "Detected in many" 4 "Esophageal apical cells: 4926.0" "Cell type enriched" "Detected in single" 4 "endothelial cell: 1.5" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 342.1;Rectum Adenocarcinoma (TCGA): 371.8" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "neutrophil: 3.7" "Lineage enhanced" "Detected in single" "granulocytes: 3.7" "Group enriched" "Detected in some" 6 "colorectal cancer: 29.2;Gastric cancer: 13.6" "Breast - Breast glandular cells (progenitors), Colon - Colon enterocytes, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Ductal cells, Prostate - Urothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA013844 Approved "Secreted to digestive system" "No annotated function" NA NA 16000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 84: Apical squamous epithelium - Cornification" 4 "HPA013844: " "unprognostic (1.95e-1)" "unprognostic (5.02e-3)" "unprognostic (1.65e-1)" "unprognostic (4.85e-3)" "unprognostic (1.07e-1)" "unprognostic (3.89e-2)" "unprognostic (1.33e-3)" "unprognostic (1.45e-1)" "unprognostic (2.85e-2)" "unprognostic (2.50e-2)" "unprognostic (1.20e-1)" "unprognostic (9.92e-2)" "unprognostic (1.86e-1)" "unprognostic (1.18e-1)" "unprognostic (7.74e-3)" "unprognostic (1.51e-2)" "unprognostic (8.16e-3)" "unprognostic (2.92e-1)" "unprognostic (3.61e-2)" "unprognostic (1.87e-3)" "unprognostic (1.96e-1)" "unprognostic (1.68e-1)" "unprognostic (1.63e-3)" "unprognostic (1.59e-1)" FAM43A FLJ90022 ENSG00000185112 "Family with sequence similarity 43 member A" Q8N2R8 3 194685883-194689037 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 47.6" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 97.5;Extravillous trophoblasts: 128.3;Lymphatic endothelial cells: 122.3;Podocytes: 53.9;Prostatic glandular cells: 82.1;Respiratory ionocytes: 101.6;Syncytiotrophoblasts: 203.9;Vascular endothelial cells: 88.7" "Cell type enhanced" "Detected in many" "endothelial cell: 56.2;fibroblast: 67.5;lower rhombic lip: 59.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 4.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Skeletal muscle - Fibroblasts, Skin - Hair cortex cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048345 Uncertain Approved Vesicles NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 16 Vesicles "HPA048345: " "unprognostic (1.69e-1)" "unprognostic (1.47e-1)" "unprognostic (5.57e-2)" "unprognostic (6.22e-2)" "unprognostic (1.97e-1)" "unprognostic (1.18e-1)" "unprognostic (5.86e-3)" "unprognostic (5.44e-2)" "unprognostic (4.78e-2)" "unprognostic (1.84e-1)" "unprognostic (1.89e-3)" "unprognostic (3.34e-2)" "unprognostic (1.10e-2)" "unprognostic (5.07e-2)" "unprognostic (6.66e-2)" "unprognostic (1.30e-1)" "unprognostic (9.06e-2)" "unprognostic (2.26e-3)" "unprognostic (1.89e-2)" "unprognostic (1.17e-1)" "unprognostic (1.12e-1)" "unprognostic (1.11e-2)" "unprognostic (1.16e-1)" "unprognostic (4.95e-2)" "unprognostic (5.20e-2)" "unprognostic (3.82e-1)" "unprognostic (8.38e-3)" "unprognostic (4.37e-2)" "unprognostic (2.18e-1)" "unprognostic (8.66e-3)" "unprognostic (3.63e-1)" FAM43B FLJ44952 ENSG00000183114 "Family with sequence similarity 43 member B" Q6ZT52 1 20552573-20555020 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adrenal gland: 21.1;brain: 14.5" "Cell type enhanced" "Detected in some" "Adrenal cortex cells: 4.7;Astrocytes: 3.9;Brain excitatory neurons: 6.1;Brain inhibitory neurons: 9.0;Ependymal cells: 3.8;Fibroblasts: 3.2;Other brain neurons: 13.1;Retinal amacrine cells: 3.5;Tuft cells: 11.5" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 7.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Adrenocortical cancer: 3.8;Bone cancer: 3.3;Rhabdoid: 3.5" "Lung - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050813 Approved Approved Cytosol NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 45: Non-specific - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" Cytosol "HPA050813: " "unprognostic (3.10e-3)" "unprognostic (1.35e-2)" "unprognostic (6.87e-2)" "unprognostic (7.34e-3)" "unprognostic (1.79e-2)" "unprognostic (7.26e-2)" FAM47A MGC27003 ENSG00000185448 "Family with sequence similarity 47 member A" Q5JRC9 X 34129752-34132314 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 28 "testis: 2.7" "Group enriched" "Detected in some" 49 "Early spermatids: 9.8;Late primary spermatocytes: 8.5;Late spermatids: 3.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" HPA000610 Uncertain NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 53: Neurons - Mixed function" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" 1 "HPA000610: " FAM47B FLJ35782 ENSG00000189132 "Family with sequence similarity 47 member B" Q8NA70 X 34942796-34944915 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 88 "testis: 8.8" "Group enriched" "Detected in some" 166 "Early spermatids: 49.4;Late primary spermatocytes: 38.7;Late spermatids: 39.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "HPA046829, HPA050996" Uncertain NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 2 "HPA046829: , HPA050996: " FAM47C ENSG00000198173 "Family with sequence similarity 47 member C" Q5HY64 X 37008366-37011664 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 18 "testis: 2.7" "Group enriched" "Detected in some" 7 "Early spermatids: 7.8;Late primary spermatocytes: 8.8;Late spermatids: 3.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" FAM47E "FLJ42946, LOC100129583" ENSG00000189157 "Family with sequence similarity 47 member E" Q6ZV65 4 76214040-76283783 "Predicted intracellular proteins" "Chromatin regulator" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 21.0;Bergmann glia: 17.5;Brain excitatory neurons: 12.5;Brain inhibitory neurons: 11.3;Choroid plexus epithelial cells: 43.4;Early spermatids: 12.6;Ependymal cells: 48.6;Late primary spermatocytes: 15.4;Oligodendrocytes: 19.0;Other brain neurons: 15.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA053331 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 27: Breast cancer - Unknown function" "Cluster 28: Astrocytes - Homeostasis & neuron support" 1 "Plasma membrane, Cytosol" Nucleoplasm "HPA053331: " "unprognostic (1.17e-1)" "unprognostic (1.29e-1)" "unprognostic (4.48e-1)" "unprognostic (8.37e-2)" "unprognostic (2.31e-1)" "unprognostic (1.40e-1)" "unprognostic (3.01e-3)" "unprognostic (2.69e-1)" "unprognostic (1.20e-2)" "validated prognostic favorable (8.94e-10)" "validated prognostic favorable (1.07e-4)" "unprognostic (3.47e-3)" "unprognostic (4.30e-2)" "unprognostic (3.27e-2)" "unprognostic (1.33e-2)" "unprognostic (8.31e-2)" "unprognostic (2.05e-2)" "unprognostic (1.51e-1)" "unprognostic (2.68e-2)" "unprognostic (1.72e-1)" "unprognostic (1.40e-2)" "unprognostic (3.70e-2)" "unprognostic (4.93e-2)" "unprognostic (8.71e-2)" "unprognostic (4.69e-2)" "unprognostic (2.16e-2)" "unprognostic (4.70e-2)" "unprognostic (1.97e-1)" "unprognostic (4.54e-2)" "unprognostic (1.14e-1)" FAM47E-STBD1 ENSG00000272414 "FAM47E-STBD1 readthrough" 4 76251721-76311129 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Adipocytes: 42.0;Cardiomyocytes: 72.6;Fallopian tube ciliated cells: 11.9;Myonuclei: 16.9;Podocytes: 14.7;Respiratory ciliated cells: 14.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA053331 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 27: Non-specific - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" "Plasma membrane, Cytosol" Nucleoplasm "HPA053331: " "unprognostic (2.37e-2)" "unprognostic (3.50e-1)" "unprognostic (1.46e-2)" "unprognostic (6.96e-2)" "unprognostic (1.89e-2)" FAM50A "9F, DXS9928E, HXC-26, XAP5" ENSG00000071859 "Family with sequence similarity 50 member A" Q14320 X 154444141-154450654 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 201.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003585 Supported Supported Nucleoplasm NA NA 9500 "Cluster 25: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 36: Non-specific - mRNA processing" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 28 Nucleoplasm "HPA003585: " "unprognostic (2.80e-1)" "unprognostic (1.30e-1)" "unprognostic (2.94e-1)" "unprognostic (5.93e-3)" "unprognostic (2.47e-3)" "unprognostic (3.22e-3)" "unprognostic (4.71e-2)" "unprognostic (4.41e-2)" "unprognostic (2.75e-1)" "unprognostic (4.82e-2)" "unprognostic (7.17e-2)" "unprognostic (8.47e-3)" "unprognostic (1.14e-1)" "validated prognostic unfavorable (7.61e-6)" "validated prognostic unfavorable (1.37e-4)" "unprognostic (2.15e-1)" "unprognostic (2.54e-2)" "unprognostic (1.80e-1)" "unprognostic (3.50e-2)" "unprognostic (3.15e-1)" "unprognostic (2.74e-2)" "unprognostic (4.39e-3)" "unprognostic (2.02e-2)" "unprognostic (4.72e-2)" "unprognostic (1.42e-1)" "potential prognostic favorable (9.59e-4)" "unprognostic (1.63e-1)" "unprognostic (2.28e-1)" "unprognostic (1.56e-1)" "unprognostic (2.20e-2)" "unprognostic (9.94e-2)" FAM50B "D6S2654E, X5L" ENSG00000145945 "Family with sequence similarity 50 member B" Q9Y247 6 3849373-3851320 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Loop of henle epithelial cells: 2.1;Papillary tip epithelial cells: 1.8;Podocytes: 1.0;Proximal tubule cells: 1.2;Renal collecting duct intercalated cells: 1.2;Renal collecting duct principal cells: 2.0;Thymic myoid cells: 1.4" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA064111, HPA067817" Approved Approved "Nucleoplasm,Cytokinetic bridge,Midbody" Yes NA "Cluster 33: Non-specific - ATP binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 33: Neurons - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 43 Nucleoplasm "Cytokinetic bridge, Midbody" "HPA064111: , HPA067817: " "unprognostic (1.21e-1)" "unprognostic (9.61e-2)" "unprognostic (6.32e-2)" "unprognostic (2.13e-1)" "unprognostic (3.85e-3)" "unprognostic (2.26e-2)" "unprognostic (5.50e-3)" "unprognostic (1.99e-3)" "unprognostic (1.30e-1)" "unprognostic (1.54e-1)" "potential prognostic favorable (8.10e-9)" "unprognostic (9.00e-2)" "potential prognostic favorable (8.15e-4)" "unprognostic (1.41e-2)" "unprognostic (3.20e-1)" "unprognostic (3.41e-1)" "unprognostic (1.40e-1)" "unprognostic (1.06e-1)" "unprognostic (4.12e-3)" "unprognostic (1.69e-1)" "unprognostic (3.55e-1)" "unprognostic (2.52e-1)" "unprognostic (1.21e-1)" "unprognostic (2.35e-1)" "unprognostic (1.51e-1)" "unprognostic (1.30e-2)" "unprognostic (1.52e-1)" "unprognostic (2.22e-1)" "unprognostic (1.11e-1)" "unprognostic (3.10e-1)" "unprognostic (1.71e-1)" FAM53A DNTNP ENSG00000174137 "Family with sequence similarity 53 member A" Q6NSI3 4 1617915-1684313 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 12.9" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 15.3;Early primary spermatocytes: 30.9;Endometrial luminal cells: 12.5;Lactotrophs: 34.7;Oligodendrocytes: 13.2;Somatotrophs: 26.5;Thyrotrophs: 18.8;Undifferentiated spermatogonia: 13.1" "Cell type enhanced" "Detected in all" "oligodendrocyte: 17.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036452, HPA058138" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 67: Testis - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 27: Breast cancer - Unknown function" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" "Nucleoplasm, Plasma membrane" "HPA036452: , HPA058138: " "unprognostic (1.95e-2)" "unprognostic (2.35e-1)" "unprognostic (2.33e-1)" "unprognostic (3.12e-2)" "unprognostic (3.12e-1)" "unprognostic (2.84e-3)" "potential prognostic unfavorable (2.64e-5)" "unprognostic (2.58e-3)" "unprognostic (1.34e-2)" "unprognostic (1.38e-2)" "unprognostic (4.60e-2)" "unprognostic (7.72e-2)" "unprognostic (1.62e-2)" "unprognostic (8.00e-2)" "unprognostic (3.45e-3)" "unprognostic (2.92e-1)" "unprognostic (1.16e-2)" "unprognostic (1.10e-1)" "unprognostic (1.72e-2)" "unprognostic (7.90e-2)" "unprognostic (5.39e-2)" "unprognostic (3.14e-3)" "unprognostic (1.72e-1)" FAM53B "bA12J10.2, KIAA0140, smp" ENSG00000189319 "Family with sequence similarity 53 member B" Q14153 10 124619292-124744378 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Early spermatids: 15.0;Epicardial cells: 2.3;Late primary spermatocytes: 10.7;Late spermatids: 4.0;Oocytes: 4.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Spleen - B-cells (Spleen), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037751, HPA037752" Approved Approved Cytosol NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 11 Cytosol "HPA037751: , HPA037752: " "unprognostic (1.03e-1)" "unprognostic (1.55e-1)" "potential prognostic favorable (2.36e-5)" "unprognostic (7.13e-2)" "unprognostic (1.08e-1)" "unprognostic (1.03e-2)" "unprognostic (2.81e-1)" "unprognostic (4.02e-3)" "potential prognostic favorable (2.67e-5)" "unprognostic (4.32e-2)" "validated prognostic favorable (3.98e-8)" "validated prognostic favorable (8.72e-4)" "unprognostic (4.71e-2)" "unprognostic (3.60e-2)" "unprognostic (1.33e-1)" "unprognostic (8.19e-3)" "unprognostic (1.73e-1)" "unprognostic (1.78e-1)" "unprognostic (8.33e-2)" "unprognostic (1.26e-2)" "unprognostic (3.14e-2)" "validated prognostic favorable (2.13e-4)" "validated prognostic favorable (9.98e-4)" "unprognostic (2.47e-1)" "unprognostic (5.40e-2)" "unprognostic (6.32e-2)" "unprognostic (1.83e-1)" "unprognostic (2.12e-3)" "unprognostic (1.88e-1)" "unprognostic (1.97e-1)" "unprognostic (2.66e-1)" FAM53C C5orf6 ENSG00000120709 "Family with sequence similarity 53 member C" Q9NYF3 5 138331935-138349729 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 388.8;Late spermatids: 876.6;Neutrophils: 425.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "neutrophil: 29.5" "Lineage enriched" "Detected in all" 6 "granulocytes: 29.5" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Spleen - Neutrophils_2, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042796 Approved NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 33 "HPA042796: " "unprognostic (1.17e-3)" "unprognostic (1.19e-1)" "unprognostic (1.78e-1)" "unprognostic (1.17e-2)" "unprognostic (2.27e-1)" "unprognostic (1.62e-1)" "unprognostic (2.44e-1)" "unprognostic (2.21e-3)" "unprognostic (1.82e-1)" "unprognostic (3.50e-2)" "potential prognostic favorable (1.21e-4)" "unprognostic (2.66e-2)" "unprognostic (2.98e-1)" "unprognostic (1.08e-3)" "unprognostic (4.84e-3)" "unprognostic (1.68e-1)" "unprognostic (6.73e-3)" "unprognostic (2.02e-1)" "unprognostic (1.36e-1)" "unprognostic (1.93e-2)" "unprognostic (8.67e-3)" "unprognostic (9.07e-2)" "unprognostic (5.72e-2)" "unprognostic (1.60e-1)" "unprognostic (1.34e-2)" "unprognostic (2.03e-1)" "unprognostic (1.06e-1)" "unprognostic (6.17e-2)" "unprognostic (2.05e-1)" "unprognostic (8.27e-3)" "unprognostic (6.33e-2)" FAM72A "LMPIP, MGC57827, p17, RP11-312O7.1, UGENE" ENSG00000196550 "Family with sequence similarity 72 member A" Q5TYM5 1 206186179-206204414 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 10.3" "Cell type enhanced" "Detected in some" "Early primary spermatocytes: 8.5;Early spermatids: 12.4;Epicardial cells: 40.9;Kupffer cells: 12.3;Late primary spermatocytes: 49.7;Late spermatids: 12.1;Paneth cells: 7.7" "Group enriched" "Detected in some" 4 "central nervous system macrophage: 5.1;endothelial cell: 2.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Mitotic cells (Minor salivary gland), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "HPA043271, HPA067321" Uncertain Approved "Vesicles,Plasma membrane,Cytosol" NA Yes "Cluster 33: Non-specific - ATP binding" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 25: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 2 Vesicles "Plasma membrane, Cytosol" "HPA043271: , HPA067321: " "unprognostic (3.72e-2)" "unprognostic (2.37e-2)" "unprognostic (1.38e-1)" "unprognostic (1.34e-1)" "unprognostic (1.40e-1)" "unprognostic (2.66e-3)" "unprognostic (7.01e-2)" "unprognostic (4.55e-3)" "unprognostic (3.69e-2)" "unprognostic (4.54e-3)" "unprognostic (1.55e-3)" "potential prognostic unfavorable (2.52e-5)" "potential prognostic unfavorable (5.22e-5)" "potential prognostic unfavorable (1.38e-5)" "unprognostic (1.52e-3)" "unprognostic (3.52e-2)" "unprognostic (1.61e-1)" "unprognostic (4.21e-2)" "unprognostic (8.07e-2)" "unprognostic (1.94e-1)" "unprognostic (8.43e-2)" "unprognostic (2.09e-1)" "unprognostic (6.24e-2)" "unprognostic (3.18e-2)" "unprognostic (5.95e-2)" "unprognostic (2.31e-1)" "unprognostic (1.15e-1)" "unprognostic (1.15e-1)" "unprognostic (1.14e-1)" FAM72B RP11-439A17.6 ENSG00000188610 "Family with sequence similarity 72 member B" Q86X60 1 121167646-121185539 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.8;lymphoid tissue: 9.6" "Cell type enhanced" "Detected in some" "Early primary spermatocytes: 10.9;Early spermatids: 10.9;Epicardial cells: 18.2;Erythrocyte progenitors: 7.2;Hofbauer cells: 11.7;Kupffer cells: 13.3;Late primary spermatocytes: 32.1;Late spermatids: 30.9;Megakaryocyte progenitors: 7.3;Monocyte progenitors: 9.1;Tuft cells: 11.5" "Cell type enhanced" "Detected in single" "central nervous system macrophage: 1.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Mitotic cells (Minor salivary gland), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach)" "HPA043271, HPA067321" Uncertain Approved "Vesicles,Plasma membrane,Cytosol" NA Yes "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 25: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Non-specific - Cell proliferation" Vesicles "Plasma membrane, Cytosol" "HPA043271: , HPA067321: " "unprognostic (4.68e-3)" "unprognostic (4.54e-2)" "unprognostic (4.15e-1)" "unprognostic (1.63e-3)" "unprognostic (6.16e-3)" "unprognostic (1.51e-2)" "unprognostic (4.47e-1)" "unprognostic (1.94e-2)" "unprognostic (2.29e-1)" "potential prognostic unfavorable (4.63e-5)" "potential prognostic unfavorable (2.93e-6)" "validated prognostic unfavorable (1.34e-5)" "validated prognostic unfavorable (5.80e-4)" "unprognostic (1.50e-2)" "unprognostic (1.95e-1)" "unprognostic (3.19e-1)" "unprognostic (6.31e-2)" "unprognostic (2.92e-3)" "potential prognostic unfavorable (5.98e-5)" "unprognostic (1.62e-1)" "unprognostic (8.36e-2)" "unprognostic (1.62e-1)" "unprognostic (5.53e-2)" "unprognostic (4.44e-1)" "unprognostic (6.09e-2)" FAM72C RP5-998N21.9 ENSG00000263513 "Family with sequence similarity 72 member C" H0Y354 1 143955287-143971986 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "bone marrow: 2.7;lymphoid tissue: 4.9" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 2.5;Differentiating spermatogonia: 4.6;Early primary spermatocytes: 6.8;Extravillous trophoblasts: 5.8;Hofbauer cells: 2.8;Kupffer cells: 3.1;Late primary spermatocytes: 6.8;Migrating cytotrophoblasts: 3.2;Monocyte progenitors: 3.6;Oocytes: 4.6;Paneth cells: 7.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach)" "HPA043271, HPA067321" Uncertain Approved "Vesicles,Plasma membrane,Cytosol" NA Yes "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 45: Non-specific - Nuclear processes" "Cluster 27: Non-specific - Cell proliferation" Vesicles "Plasma membrane, Cytosol" "HPA043271: , HPA067321: " "unprognostic (1.43e-2)" "unprognostic (2.19e-1)" "unprognostic (9.67e-3)" "unprognostic (3.02e-2)" "unprognostic (1.76e-1)" "unprognostic (2.19e-1)" "unprognostic (1.54e-3)" "potential prognostic unfavorable (1.33e-5)" "potential prognostic unfavorable (7.12e-6)" "unprognostic (4.94e-3)" "unprognostic (4.42e-2)" "unprognostic (3.41e-1)" "unprognostic (1.22e-1)" "unprognostic (2.13e-2)" "unprognostic (1.74e-1)" "unprognostic (1.30e-1)" "unprognostic (1.21e-1)" "unprognostic (2.66e-1)" "unprognostic (2.89e-2)" FAM72D ENSG00000215784 "Family with sequence similarity 72 member D" Q6L9T8 1 145095974-145112696 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 3.7;lymphoid tissue: 6.2" "Cell type enhanced" "Detected in some" "Colonocytes: 4.8;Differentiating spermatogonia: 7.8;Early primary spermatocytes: 13.5;Enteric transient amplifying cells: 5.4;Epicardial cells: 4.5;Erythrocyte progenitors: 4.6;Extravillous trophoblasts: 7.2;Goblet cells: 4.6;Late primary spermatocytes: 14.9;Megakaryocyte progenitors: 4.9;Monocyte progenitors: 8.7;Oocytes: 4.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Mitotic cells (Minor salivary gland), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach)" "HPA043271, HPA067321" Uncertain Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 45: Non-specific - Nuclear processes" "Cluster 27: Non-specific - Cell proliferation" 3 Vesicles "Plasma membrane, Cytosol" "HPA043271: , HPA067321: " "unprognostic (4.49e-3)" "unprognostic (1.04e-2)" "unprognostic (2.48e-1)" "unprognostic (2.61e-2)" "unprognostic (1.19e-1)" "unprognostic (2.12e-2)" "unprognostic (9.01e-2)" "unprognostic (1.35e-1)" "unprognostic (3.26e-2)" "potential prognostic unfavorable (6.76e-6)" "validated prognostic unfavorable (1.62e-5)" "validated prognostic unfavorable (2.04e-5)" "unprognostic (4.17e-2)" "unprognostic (3.26e-1)" "unprognostic (4.34e-2)" "unprognostic (6.93e-2)" "unprognostic (1.32e-3)" "unprognostic (1.74e-2)" "unprognostic (3.11e-1)" "unprognostic (4.23e-3)" "unprognostic (4.27e-2)" "unprognostic (1.56e-1)" "unprognostic (6.91e-2)" "unprognostic (6.02e-3)" FAM76A MGC34648 ENSG00000009780 "Family with sequence similarity 76 member A" Q8TAV0 1 27725961-27763116 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 168.2;Late spermatids: 150.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044762, HPA077897" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 40: Non-specific - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 37: Non-specific - mRNA processing" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 1 "Nucleoplasm, Cytosol" "HPA044762: , HPA077897: " "unprognostic (9.72e-3)" "unprognostic (9.60e-2)" "unprognostic (1.16e-2)" "unprognostic (1.06e-1)" "unprognostic (1.57e-1)" "unprognostic (1.65e-1)" "unprognostic (6.67e-2)" "unprognostic (3.91e-1)" "unprognostic (2.20e-3)" "potential prognostic unfavorable (7.98e-4)" "potential prognostic favorable (6.24e-5)" "unprognostic (4.21e-3)" "potential prognostic favorable (8.96e-7)" "unprognostic (7.04e-3)" "unprognostic (1.18e-1)" "unprognostic (2.81e-3)" "unprognostic (2.48e-1)" "unprognostic (1.61e-1)" "unprognostic (1.53e-1)" "unprognostic (1.76e-1)" "unprognostic (4.34e-2)" "unprognostic (1.15e-1)" "unprognostic (1.82e-2)" "unprognostic (3.32e-2)" "unprognostic (1.75e-1)" "unprognostic (3.55e-2)" "unprognostic (1.28e-2)" "unprognostic (1.40e-1)" "unprognostic (1.55e-1)" "unprognostic (4.27e-2)" "unprognostic (2.71e-1)" FAM76B MGC33371 ENSG00000077458 "Family with sequence similarity 76 member B" Q5HYJ3 11 95768953-95790409 "Predicted intracellular proteins, Predicted membrane proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 37.3" "Group enriched" "Detected in all" 4 "Early spermatids: 320.0;Late spermatids: 665.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036608 Approved Approved "Nucleoplasm,Nucleoli fibrillar center" No No "Cluster 33: Non-specific - ATP binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 10 Nucleoplasm "Nucleoli fibrillar center" "HPA036608: " "unprognostic (5.94e-3)" "unprognostic (1.32e-2)" "unprognostic (7.93e-2)" "unprognostic (1.08e-2)" "unprognostic (1.19e-1)" "unprognostic (5.21e-2)" "unprognostic (1.88e-1)" "unprognostic (1.88e-2)" "unprognostic (5.80e-3)" "unprognostic (6.21e-3)" "validated prognostic favorable (7.68e-5)" "validated prognostic favorable (4.10e-4)" "unprognostic (1.36e-1)" "unprognostic (3.06e-1)" "unprognostic (3.70e-2)" "unprognostic (1.72e-1)" "unprognostic (1.62e-2)" "unprognostic (1.93e-1)" "unprognostic (3.03e-2)" "unprognostic (2.16e-1)" "unprognostic (3.09e-1)" "potential prognostic unfavorable (4.04e-4)" "unprognostic (3.65e-3)" "unprognostic (2.37e-2)" "unprognostic (1.40e-3)" "unprognostic (7.07e-2)" "unprognostic (4.73e-2)" "unprognostic (7.65e-2)" "unprognostic (3.71e-1)" "unprognostic (4.33e-2)" "unprognostic (8.58e-2)" FAM78A "C9orf59, FLJ00024" ENSG00000126882 "Family with sequence similarity 78 member A" Q5JUQ0 9 131258076-131277365 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 58.8;testis: 30.0" "Cell type enhanced" "Detected in some" "Early spermatids: 112.2;Extravillous trophoblasts: 57.9;Hofbauer cells: 42.5;Late spermatids: 185.1;Microglia: 53.1;Monocyte progenitors: 36.2;NK-cells: 33.2;Platelets: 38.1;Retinal bipolar cells: 117.2;T-cells: 32.8" "Group enriched" "Detected in many" 5 "central nervous system macrophage: 62.0;leukocyte: 51.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Leukemia: 42.0;lymphoma: 25.8;Myeloma: 17.1" "Adrenal gland - Macrophages, Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021472, HPA023914" Uncertain Uncertain Nucleoplasm,Vesicles "Intracellular and membrane" "No annotated function" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 51: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 2 "Nucleoplasm, Vesicles" "HPA021472: , HPA023914: " "unprognostic (3.91e-2)" "unprognostic (1.75e-2)" "unprognostic (1.21e-2)" "unprognostic (7.13e-2)" "unprognostic (1.40e-1)" "unprognostic (8.40e-2)" "unprognostic (3.84e-1)" "unprognostic (1.63e-1)" "potential prognostic favorable (2.81e-4)" "unprognostic (5.83e-3)" "unprognostic (5.37e-2)" "unprognostic (3.23e-2)" "unprognostic (9.42e-3)" "unprognostic (3.85e-2)" "unprognostic (3.43e-3)" "potential prognostic favorable (5.20e-4)" "unprognostic (9.64e-2)" "unprognostic (3.60e-2)" "unprognostic (1.79e-1)" "unprognostic (3.61e-1)" "unprognostic (3.63e-1)" "unprognostic (4.90e-2)" "unprognostic (4.20e-2)" "unprognostic (5.90e-2)" "unprognostic (9.29e-2)" "unprognostic (3.41e-1)" "unprognostic (6.03e-2)" "unprognostic (2.02e-2)" "unprognostic (9.65e-2)" "unprognostic (2.44e-1)" "unprognostic (1.48e-1)" FAM78B ENSG00000188859 "Family with sequence similarity 78 member B" Q5VT40 1 166057426-166167001 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Cone photoreceptor cells: 310.5;Retinal horizontal cells: 615.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 4.4" "Colon - Enteric glia cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA052789, HPA073246" Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 53: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 109: Neurons - Neuronal signaling" "Golgi apparatus, Vesicles" "HPA052789: , HPA073246: " "unprognostic (7.44e-3)" "unprognostic (3.06e-2)" "unprognostic (6.45e-3)" "unprognostic (4.75e-3)" "unprognostic (1.33e-1)" "unprognostic (8.88e-2)" "unprognostic (1.73e-1)" "unprognostic (1.54e-1)" "unprognostic (1.97e-2)" FAM81A MGC26690 ENSG00000157470 "Family with sequence similarity 81 member A" Q8TBF8 15 59372693-59523555 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 26.3" "Cell type enhanced" "Detected in many" "Ependymal cells: 180.0;Epididymal basal cells: 97.3;Podocytes: 162.9;Renal collecting duct principal cells: 160.1;Respiratory ciliated cells: 122.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 5.1;plasmacytoid DC: 11.7" "Lineage enriched" "Detected in many" 5 "dendritic cells: 11.7" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001847, HPA065797" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 78: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 35: Neurons - Synaptic function & neurogenesis" 5 Nucleoplasm Cytosol "HPA001847: , HPA065797: " "unprognostic (3.17e-2)" "unprognostic (1.13e-1)" "unprognostic (1.19e-1)" "unprognostic (1.18e-2)" "unprognostic (3.68e-1)" "unprognostic (1.05e-1)" "unprognostic (1.52e-1)" "unprognostic (1.60e-1)" "unprognostic (4.71e-2)" "unprognostic (2.14e-3)" "unprognostic (7.80e-2)" "potential prognostic favorable (7.96e-4)" "unprognostic (2.13e-1)" "unprognostic (2.97e-3)" "unprognostic (1.82e-1)" "unprognostic (1.38e-1)" "unprognostic (4.10e-2)" "unprognostic (3.75e-2)" "unprognostic (3.59e-2)" "unprognostic (2.19e-2)" "unprognostic (1.52e-1)" "unprognostic (3.58e-1)" "unprognostic (2.82e-1)" "unprognostic (2.96e-2)" "unprognostic (9.10e-3)" "unprognostic (3.70e-3)" "unprognostic (3.23e-1)" "unprognostic (3.80e-2)" FAM81B FLJ25333 ENSG00000153347 "Family with sequence similarity 81 member B" Q96LP2 5 95391366-95450454 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "choroid plexus: 58.9;fallopian tube: 45.4;testis: 78.7" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 175.1;Early spermatids: 955.3;Endometrial ciliated cells: 213.5;Ependymal cells: 238.0;Epididymal efferent duct ciliated cells: 382.8;Fallopian tube ciliated cells: 458.0;Late primary spermatocytes: 323.4;Late spermatids: 2644.1;Respiratory ciliated cells: 395.5" "Group enriched" "Detected in many" 31 "choroid plexus epithelial cell: 187.0;ependymal cell: 292.5" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 11.2" "Region enhanced" "Detected in all" "choroid plexus: 34.5" "Immune cell enriched" "Detected in single" 62 "basophil: 6.7" "Lineage enriched" "Detected in single" 62 "granulocytes: 6.7" "Cancer enhanced" "Detected in single" "Bile duct cancer: 2.3" "Lung - Respiratory ciliated cells, Pituitary gland - Thyrotropes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" HPA072554 Approved NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 8 "HPA072554: " "unprognostic (2.36e-2)" "unprognostic (2.58e-2)" "unprognostic (6.47e-2)" "unprognostic (4.40e-3)" "unprognostic (7.24e-2)" "unprognostic (9.72e-3)" "unprognostic (5.60e-2)" "unprognostic (5.42e-3)" "unprognostic (1.52e-1)" "unprognostic (2.37e-1)" "unprognostic (8.22e-2)" "unprognostic (3.73e-2)" "unprognostic (3.50e-2)" "unprognostic (1.99e-2)" "unprognostic (4.76e-2)" "unprognostic (5.21e-2)" "unprognostic (1.21e-1)" "unprognostic (1.60e-1)" FAM83A "BJ-TSA-9, MGC14128" ENSG00000147689 "Family with sequence similarity 83 member A" Q86UY5 8 123178960-123210079 "Predicted intracellular proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "esophagus: 59.6" "Group enriched" "Detected in many" 4 "Esophageal apical cells: 1358.6;Ocular epithelial cells: 644.0" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 94.6;Head and Neck Squamous Cell Carcinoma (TCGA): 143.3" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 76.6" "Adipose visceral - Mesothelial cells, Lung - Respiratory ciliated cells, Prostate - Urothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA052615 Approved Nucleoplasm,Cytosol NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 23 Nucleoplasm Cytosol "HPA052615: " "unprognostic (1.57e-1)" "unprognostic (3.07e-2)" "unprognostic (4.63e-2)" "unprognostic (2.21e-3)" "unprognostic (1.12e-1)" "unprognostic (2.70e-1)" "unprognostic (2.11e-1)" "validated prognostic unfavorable (4.39e-9)" "validated prognostic unfavorable (4.98e-4)" "unprognostic (4.37e-3)" "potential prognostic unfavorable (3.44e-5)" "unprognostic (1.77e-1)" "unprognostic (3.53e-2)" "validated prognostic unfavorable (5.30e-6)" "validated prognostic unfavorable (6.79e-4)" "unprognostic (3.00e-1)" "unprognostic (1.98e-1)" "unprognostic (2.53e-1)" "unprognostic (6.43e-2)" "unprognostic (1.92e-1)" "unprognostic (1.92e-2)" FAM83B "C6orf143, FLJ30642" ENSG00000168143 "Family with sequence similarity 83 member B" Q5T0W9 6 54846771-54945099 "Predicted intracellular proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 12.4;skin 1: 24.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 258.9;Epididymal basal cells: 125.3;Esophageal basal cells: 128.0;Esophageal suprabasal cells: 145.8;Ocular epithelial cells: 351.5;Renal collecting duct principal cells: 108.7;Suprabasal keratinocytes: 352.3;Urothelial cells: 253.4" "Group enriched" "Detected in some" 4 "deep-layer corticothalamic and 6b: 2.5;splatter: 1.0;thalamic excitatory: 1.5" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 23.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Esophageal cancer: 12.9" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary gland basal cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA031464, HPA031465" Enhanced NA NA "Cluster 58: Skin - Keratinization" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 25 "HPA031464: , HPA031465: " "unprognostic (4.01e-2)" "unprognostic (7.73e-2)" "unprognostic (2.91e-1)" "unprognostic (1.82e-1)" "unprognostic (1.45e-1)" "unprognostic (1.89e-1)" "unprognostic (3.35e-2)" "unprognostic (9.13e-2)" "potential prognostic unfavorable (1.14e-8)" "unprognostic (7.57e-2)" "unprognostic (2.39e-2)" "unprognostic (4.40e-2)" "unprognostic (1.40e-3)" "unprognostic (2.67e-1)" "unprognostic (5.89e-2)" "unprognostic (9.42e-2)" "unprognostic (2.63e-1)" "unprognostic (9.17e-2)" "unprognostic (1.82e-1)" "unprognostic (4.47e-1)" "unprognostic (1.37e-2)" FAM83C "C20orf128, dJ614O4.7" ENSG00000125998 "Family with sequence similarity 83 member C" Q9BQN1 20 35285731-35292425 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "cervix: 10.3;esophagus: 31.5;skin 1: 40.1;vagina: 14.2" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 28.7;Early spermatids: 15.2;Esophageal apical cells: 43.5;Esophageal basal cells: 46.1;Esophageal suprabasal cells: 64.8;Late spermatids: 8.3;Suprabasal keratinocytes: 66.9" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 17.1;Head and Neck Squamous Cell Carcinoma (TCGA): 24.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "Bladder cancer: 1.2;Esophageal cancer: 1.8;head and neck cancer: 4.2" "Prostate - Urothelial cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "CAB034227, HPA049978" Uncertain NA NA "Cluster 58: Skin - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 1 "CAB034227: , HPA049978: " "unprognostic (5.37e-2)" "unprognostic (6.30e-2)" "unprognostic (8.85e-3)" "unprognostic (4.57e-2)" "unprognostic (2.80e-1)" "unprognostic (3.75e-1)" FAM83D "C20orf129, CHICA, dJ616B8.3" ENSG00000101447 "Family with sequence similarity 83 member D" Q9H4H8 20 38926312-38953106 "Disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 81.8;intestine: 76.6;smooth muscle: 88.9" "Group enriched" "Detected in many" 4 "Esophageal apical cells: 561.4;Syncytiotrophoblasts: 261.4" "Group enriched" "Detected in many" 4 "committed oligodendrocyte precursor: 33.1;hippocampal CA1-3: 10.1;medium spiny neuron: 11.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "B-cells: 1.1;NK-cells: 1.1;T-cells: 2.0" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Smooth muscle cells, Spleen - Mitotic cells (Spleen), Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA049333, HPA060854" Supported "Microtubules,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 53: Neurons - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 84: Apical squamous epithelium - Cornification" 26 "Mitotic spindle" "Microtubules, Cytokinetic bridge, Cytosol" "HPA049333: , HPA060854: " "unprognostic (2.49e-1)" "unprognostic (1.87e-2)" "unprognostic (5.33e-2)" "unprognostic (3.09e-1)" "unprognostic (1.95e-1)" "unprognostic (9.30e-2)" "unprognostic (6.62e-2)" "unprognostic (3.39e-3)" "unprognostic (9.12e-2)" "potential prognostic unfavorable (5.10e-5)" "unprognostic (6.22e-2)" "unprognostic (8.73e-3)" "potential prognostic unfavorable (5.91e-9)" "validated prognostic unfavorable (1.31e-5)" "validated prognostic unfavorable (1.00e-6)" "validated prognostic unfavorable (2.17e-5)" "validated prognostic unfavorable (1.89e-4)" "unprognostic (2.52e-3)" "unprognostic (5.35e-2)" "unprognostic (2.41e-2)" "unprognostic (2.49e-1)" "potential prognostic unfavorable (3.68e-5)" "unprognostic (2.68e-1)" "unprognostic (2.31e-2)" "unprognostic (1.70e-1)" "unprognostic (9.30e-3)" "unprognostic (2.71e-2)" "unprognostic (1.51e-2)" "unprognostic (5.19e-2)" "unprognostic (1.13e-1)" FAM83E FLJ20200 ENSG00000105523 "Family with sequence similarity 83 member E" Q2M2I3 19 48599961-48615076 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 30.9;salivary gland: 28.6;stomach 1: 35.3" "Cell type enhanced" "Detected in many" "Colonocytes: 125.6;Enteric stem cells: 72.4;Enteric transient amplifying cells: 65.9;Enterocytes: 67.6;Foveolar cells: 252.7;Goblet cells: 268.5;Neuroendocrine cells: 72.8;Respiratory secretory cells: 65.6;Tuft cells: 80.7" "Low cell type specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 12.3;Gastric cancer: 9.9" "Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Ductal cells, Prostate - Urothelial cells, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049305, HPA075968" Uncertain Approved Vesicles,Cytosol NA NA "Cluster 77: Intestine - Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 70: Intestinal goblet cells - Mucin production" 1 Cytosol Vesicles "HPA049305: , HPA075968: " "unprognostic (1.22e-1)" "unprognostic (2.98e-1)" "unprognostic (7.85e-2)" "unprognostic (1.93e-2)" "unprognostic (2.53e-1)" "unprognostic (3.09e-2)" "unprognostic (1.31e-3)" "unprognostic (9.92e-2)" "unprognostic (2.01e-1)" "unprognostic (6.84e-2)" "unprognostic (1.15e-1)" "unprognostic (6.12e-2)" "unprognostic (1.17e-1)" "unprognostic (9.84e-2)" "unprognostic (1.12e-1)" "unprognostic (3.25e-2)" "unprognostic (5.32e-2)" "unprognostic (1.74e-1)" "unprognostic (5.19e-3)" "unprognostic (1.51e-2)" "unprognostic (1.20e-1)" "unprognostic (8.22e-2)" FAM83F ENSG00000133477 "Family with sequence similarity 83 member F" Q8NEG4 22 39994954-40043534 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 18.9;testis: 38.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 88.1;Breast lactating cells: 71.3;Esophageal basal cells: 57.8;Late spermatids: 116.1;Ocular epithelial cells: 69.2;Prostatic glandular cells: 52.0;Renal collecting duct principal cells: 80.8;Suprabasal keratinocytes: 58.5" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 2.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Breast glandular cells, Colon - Colon enterocytes, Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Skin - Keratinocyte (granular), Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA051207, HPA064657" Enhanced Approved Nucleoplasm,Mitochondria NA NA "Cluster 21: Testis - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 26: Keratinocytes - Keratinization" 1 Mitochondria Nucleoplasm "HPA051207: , HPA064657: " "unprognostic (4.37e-1)" "unprognostic (4.28e-2)" "unprognostic (1.50e-1)" "unprognostic (4.79e-3)" "unprognostic (8.45e-3)" "unprognostic (6.29e-2)" "unprognostic (9.10e-2)" "unprognostic (2.42e-1)" "unprognostic (2.38e-3)" "unprognostic (4.44e-3)" "potential prognostic favorable (3.59e-5)" "unprognostic (1.86e-2)" "unprognostic (4.81e-1)" "unprognostic (5.40e-2)" "unprognostic (1.17e-1)" "unprognostic (2.22e-2)" "unprognostic (3.79e-3)" "unprognostic (2.55e-1)" "unprognostic (1.87e-1)" "unprognostic (3.64e-3)" "unprognostic (1.30e-2)" "unprognostic (2.79e-1)" "unprognostic (2.13e-1)" "unprognostic (2.75e-1)" "unprognostic (3.23e-1)" "unprognostic (1.24e-1)" FAM83G "FLJ41564, PAWS1" ENSG00000188522 "Family with sequence similarity 83 member G" A6ND36 17 18968789-19004764 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 49.7;skin 1: 65.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 80.4;Colonocytes: 36.8;Esophageal apical cells: 76.9;Esophageal basal cells: 58.9;Esophageal suprabasal cells: 106.3;Ocular epithelial cells: 50.9;Suprabasal keratinocytes: 93.3" "Cell type enhanced" "Detected in some" "leukocyte: 2.6" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 45.2" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Heart muscle - Macrophages, Skin - Keratinocyte (granular), Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA023369, HPA023940" Enhanced Supported Cytosol NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 58: Skin - Keratinization" "Cluster 44: Non-specific - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 26: Keratinocytes - Keratinization" 19 Cytosol "HPA023369: , HPA023940: " "unprognostic (1.60e-2)" "unprognostic (2.51e-3)" "unprognostic (8.11e-2)" "unprognostic (8.66e-3)" "unprognostic (1.44e-1)" "unprognostic (1.90e-1)" "unprognostic (3.75e-2)" "unprognostic (1.25e-2)" "unprognostic (2.24e-1)" "unprognostic (2.75e-2)" "unprognostic (5.71e-2)" "unprognostic (7.14e-2)" "potential prognostic unfavorable (8.65e-4)" "unprognostic (2.02e-2)" "unprognostic (1.13e-3)" "unprognostic (2.36e-1)" "unprognostic (1.45e-1)" "unprognostic (2.01e-1)" "unprognostic (2.34e-2)" "unprognostic (1.30e-1)" "unprognostic (8.90e-2)" "unprognostic (1.42e-1)" "unprognostic (2.49e-1)" "unprognostic (5.74e-3)" "unprognostic (1.67e-1)" "unprognostic (9.94e-2)" "potential prognostic favorable (6.79e-4)" "unprognostic (1.86e-1)" "unprognostic (1.42e-1)" "unprognostic (2.43e-1)" FAM83H FLJ46072 ENSG00000180921 "Family with sequence similarity 83 member H" Q6ZRV2 8 143723933-143738234 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Biomineralization "Amelogenesis imperfecta, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 68.1;skin 1: 33.5" "Group enriched" "Detected in some" 5 "Choroid plexus epithelial cells: 7.6;Distal convoluted tubule cells: 7.2;Ependymal cells: 5.6;Loop of henle epithelial cells: 11.0;Papillary tip epithelial cells: 21.7;Podocytes: 8.3;Proximal tubule cells: 7.6;Renal collecting duct intercalated cells: 9.3;Renal collecting duct principal cells: 14.2;Renal connecting tubule cells: 11.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA024505, HPA024604" Enhanced Approved Cytosol NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 17: Choroid plexus - Cilium" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 28 Cytosol "HPA024505: , HPA024604: " "unprognostic (8.41e-2)" "unprognostic (5.00e-2)" "unprognostic (2.35e-1)" "potential prognostic unfavorable (2.81e-4)" "unprognostic (1.48e-1)" "unprognostic (7.83e-2)" "unprognostic (1.07e-2)" "unprognostic (6.23e-2)" "unprognostic (4.47e-1)" "unprognostic (1.61e-1)" "unprognostic (9.37e-2)" "unprognostic (4.94e-2)" "unprognostic (3.41e-3)" "unprognostic (5.57e-2)" "potential prognostic unfavorable (3.47e-4)" "unprognostic (1.83e-1)" "unprognostic (4.68e-2)" "unprognostic (1.07e-1)" "unprognostic (2.03e-1)" "unprognostic (2.47e-1)" "unprognostic (3.82e-3)" "unprognostic (1.18e-3)" "unprognostic (3.78e-1)" "unprognostic (9.13e-2)" "unprognostic (1.95e-1)" "unprognostic (2.47e-1)" "unprognostic (4.62e-3)" "unprognostic (4.17e-1)" "unprognostic (2.09e-1)" "unprognostic (2.62e-1)" FAM86B1 MGC16279 ENSG00000186523 "Family with sequence similarity 86 member B1" Q8N7N1 8 12182096-12194133 "Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 7.3;pituitary gland: 6.9" "Cell type enhanced" "Detected in some" "Bergmann glia: 1.9;Cholangiocytes: 2.0;Choroid plexus epithelial cells: 2.6;Ependymal cells: 5.2;Epicardial cells: 2.3;Epididymal efferent duct ciliated cells: 2.9;Loop of henle epithelial cells: 2.1;Medullary thymic epithelial cells: 2.4;Papillary tip epithelial cells: 2.4;Proximal tubule cells: 3.8;Renal collecting duct principal cells: 2.5;Renal connecting tubule cells: 1.9" "Cell type enhanced" "Detected in many" "ependymal cell: 5.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 1.1;eosinophil: 1.1;neutrophil: 1.3" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.3" "Low cancer specificity" "Detected in many" "HPA041610, HPA055718" Uncertain Uncertain Vesicles NA NA "Cluster 32: Basophils - Transcription" "Cluster 65: Brain - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 34: Ciliated cells - Cilia assembly & function" Vesicles "HPA041610: , HPA055718: " "unprognostic (5.97e-3)" "unprognostic (3.87e-2)" "unprognostic (6.00e-2)" "potential prognostic unfavorable (7.15e-4)" "unprognostic (1.37e-1)" "unprognostic (1.73e-1)" "unprognostic (3.62e-2)" "unprognostic (6.06e-2)" "unprognostic (5.57e-2)" "unprognostic (7.12e-2)" "unprognostic (5.11e-1)" FAM86B2 ENSG00000145002 "Family with sequence similarity 86 member B2" P0C5J1 8 12424411-12436406 "Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Gonadotrophs: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA041610 Uncertain Uncertain Vesicles NA NA "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 55: Myocytes - Oxidative muscle function" Vesicles "HPA041610: " "unprognostic (3.78e-3)" FAM89A "C1orf153, MGC15887" ENSG00000182118 "Family with sequence similarity 89 member A" Q96GI7 1 231018958-231040254 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 56.3;placenta: 64.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 242.5;Extravillous trophoblasts: 405.2;Migrating cytotrophoblasts: 153.8;Podocytes: 154.3;Retinal pigment epithelial cells: 85.3;Rod photoreceptor cells: 89.8;Syncytiotrophoblasts: 293.6" "Cell type enhanced" "Detected in many" "endothelial cell: 95.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.4" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Endothelial cells, Heart muscle - Endothelial cells, Liver - Neutrophils, Skeletal muscle - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA059052, HPA059578" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 44: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 2 "Golgi apparatus, Vesicles" Nucleoplasm "HPA059052: , HPA059578: " "unprognostic (4.19e-2)" "unprognostic (6.64e-2)" "unprognostic (1.37e-1)" "unprognostic (1.32e-2)" "unprognostic (2.12e-2)" "unprognostic (9.07e-2)" "unprognostic (1.51e-1)" "unprognostic (1.77e-3)" "unprognostic (6.75e-2)" "unprognostic (5.10e-2)" "unprognostic (2.42e-1)" "unprognostic (3.59e-2)" "unprognostic (2.59e-2)" "unprognostic (7.17e-3)" "unprognostic (1.06e-1)" "potential prognostic unfavorable (4.68e-4)" "unprognostic (1.72e-2)" "unprognostic (1.61e-1)" "unprognostic (2.37e-1)" "unprognostic (2.36e-1)" "unprognostic (2.38e-1)" "unprognostic (1.91e-1)" "unprognostic (2.50e-3)" "unprognostic (3.46e-2)" "unprognostic (2.23e-1)" "unprognostic (1.82e-1)" "unprognostic (9.67e-2)" "unprognostic (6.68e-2)" "unprognostic (2.54e-1)" "unprognostic (3.06e-2)" "unprognostic (6.47e-3)" FAM89B "LRAP25, MTVR1" ENSG00000176973 "Family with sequence similarity 89 member B" Q8N5H3 11 65572349-65574198 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 117.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046895 Approved NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" "HPA046895: " "unprognostic (1.74e-1)" "unprognostic (3.28e-1)" "unprognostic (1.90e-1)" "unprognostic (4.34e-2)" "unprognostic (2.49e-1)" "unprognostic (3.12e-1)" "unprognostic (3.14e-1)" "unprognostic (1.99e-2)" "unprognostic (1.94e-2)" "unprognostic (1.42e-1)" "unprognostic (2.16e-1)" "unprognostic (1.74e-1)" "unprognostic (1.38e-1)" "potential prognostic unfavorable (8.99e-4)" "unprognostic (1.03e-2)" "unprognostic (1.40e-1)" "unprognostic (1.25e-3)" "unprognostic (6.03e-2)" "unprognostic (3.75e-1)" "unprognostic (6.98e-2)" "unprognostic (2.22e-1)" "unprognostic (3.25e-2)" "unprognostic (1.65e-1)" "unprognostic (1.67e-2)" "unprognostic (8.56e-2)" "unprognostic (1.24e-2)" "unprognostic (1.26e-1)" "unprognostic (1.21e-1)" "unprognostic (2.49e-1)" "unprognostic (9.41e-2)" "unprognostic (2.12e-1)" FAM8A1 AHCP ENSG00000137414 "Family with sequence similarity 8 member A1" Q9UBU6 6 17600302-17611719 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 911.1;Late primary spermatocytes: 267.0;Late spermatids: 269.3;Neutrophil progenitors: 121.9;Neutrophils: 240.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 5.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044698, HPA073675" Approved Approved "Golgi apparatus" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 55: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 25 "Golgi apparatus" "HPA044698: , HPA073675: " "unprognostic (3.51e-2)" "unprognostic (3.39e-1)" "unprognostic (1.56e-1)" "unprognostic (1.73e-1)" "unprognostic (1.83e-1)" "unprognostic (1.21e-1)" "unprognostic (2.89e-1)" "unprognostic (3.11e-2)" "unprognostic (3.93e-3)" "unprognostic (3.53e-1)" "validated prognostic favorable (2.70e-7)" "validated prognostic favorable (4.32e-5)" "unprognostic (2.71e-2)" "unprognostic (1.70e-1)" "unprognostic (2.88e-1)" "unprognostic (2.80e-2)" "unprognostic (8.23e-2)" "unprognostic (1.23e-1)" "unprognostic (1.88e-1)" "unprognostic (2.47e-2)" "unprognostic (3.92e-2)" "unprognostic (1.11e-1)" "unprognostic (1.45e-1)" "unprognostic (1.91e-1)" "unprognostic (1.15e-1)" "unprognostic (1.52e-1)" "unprognostic (1.06e-1)" "unprognostic (5.74e-3)" "unprognostic (3.31e-1)" "unprognostic (3.61e-2)" "unprognostic (2.18e-1)" FAM90A1 FLJ10408 ENSG00000171847 "Family with sequence similarity 90 member A1" Q86YD7 12 8221260-8227618 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 6.6" "Cell type enhanced" "Detected in many" "Early spermatids: 13.9;Epididymal principal cells: 6.5;Late spermatids: 5.4;Müller glia: 4.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skeletal muscle - Fibroblasts" HPA060078 Approved Nucleoplasm,Nucleoli NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 34: Non-specific - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 138 Nucleoplasm Nucleoli "HPA060078: " "unprognostic (8.88e-2)" "unprognostic (1.33e-1)" "unprognostic (8.23e-2)" "unprognostic (6.14e-3)" "unprognostic (1.21e-1)" "unprognostic (1.63e-3)" "unprognostic (7.21e-2)" "unprognostic (8.79e-2)" "potential prognostic unfavorable (3.06e-6)" "unprognostic (1.12e-1)" "unprognostic (6.08e-2)" "unprognostic (3.53e-1)" "unprognostic (2.17e-1)" "unprognostic (7.01e-2)" "unprognostic (3.73e-2)" "unprognostic (1.81e-1)" "unprognostic (7.38e-2)" "unprognostic (3.81e-3)" "unprognostic (1.97e-1)" "unprognostic (6.24e-2)" "unprognostic (3.19e-1)" "unprognostic (7.43e-2)" "unprognostic (1.24e-1)" "unprognostic (1.72e-1)" FAM90A10 FAM90A10P ENSG00000285950 "Family with sequence similarity 90 member A10" A6NDY2 8 7768977-7771988 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA060078 Approved Nucleoplasm,Nucleoli NA NA Nucleoplasm Nucleoli "HPA060078: " FAM90A11P FAM90A11 ENSG00000233115 "Family with sequence similarity 90 member A11, pseudogene" 8 8011782-8017011 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "retina: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA060078 Approved Nucleoplasm,Nucleoli NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 9: Non-specific - Receptor signaling" "Cluster 27: Breast cancer - Unknown function" Nucleoplasm Nucleoli "HPA060078: " FAM90A12P FAM90A12 ENSG00000254229 "Family with sequence similarity 90 member A12, pseudogene" A8MX19 8 8027077-8031818 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA060078 Approved Nucleoplasm,Nucleoli NA NA "Cluster 32: Cerebral cortex - Mixed function" Nucleoplasm Nucleoli "HPA060078: " FAM90A13P FAM90A13 ENSG00000223885 "Family with sequence similarity 90 member A13, pseudogene" P0C7W8 8 7279770-7282780 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA060078 Approved Nucleoplasm,Nucleoli NA NA "Cluster 48: Non-specific - Mixed function" Nucleoplasm Nucleoli "HPA060078: " FAM90A14 FAM90A14P ENSG00000285814 "Family with sequence similarity 90 member A14" P0C7W9 8 7715443-7718453 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA060078 Approved Nucleoplasm,Nucleoli NA NA Nucleoplasm Nucleoli "HPA060078: " FAM90A15P FAM90A15 ENSG00000230045 "Family with sequence similarity 90 member A15, pseudogene" P0C7V4 8 7256904-7259914 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA060078 Approved Nucleoplasm,Nucleoli NA NA "Cluster 32: Cerebral cortex - Mixed function" Nucleoplasm Nucleoli "HPA060078: " FAM90A16 FAM90A16P ENSG00000285620 "Family with sequence similarity 90 member A16" P0DV73 8 7730739-7733749 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA060078 Approved Nucleoplasm,Nucleoli NA NA Nucleoplasm Nucleoli "HPA060078: " FAM90A17 FAM90A17P ENSG00000285720 "Family with sequence similarity 90 member A17" P0DV74 8 7746034-7749044 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA060078 Approved Nucleoplasm,Nucleoli NA NA Nucleoplasm Nucleoli "HPA060078: " FAM90A18 FAM90A18P ENSG00000285913 "Family with sequence similarity 90 member A18" P0DV75 8 7723091-7726101 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA060078 Approved Nucleoplasm,Nucleoli NA NA Nucleoplasm Nucleoli "HPA060078: " FAM90A19 FAM90A19P ENSG00000285657 "Family with sequence similarity 90 member A19" P0DV76 8 7753682-7756692 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA060078 Approved Nucleoplasm,Nucleoli NA NA Nucleoplasm Nucleoli "HPA060078: " FAM90A20P FAM90A20 ENSG00000233295 "Family with sequence similarity 90 member A20, pseudogene" A6NIJ5 8 7295014-7298024 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA060078 Approved Nucleoplasm,Nucleoli NA NA "Cluster 6: Non-specific - Immune response" "Cluster 27: Breast cancer - Unknown function" Nucleoplasm Nucleoli "HPA060078: " FAM90A22 FAM90A22P ENSG00000285687 "Family with sequence similarity 90 member A22" A8MWA6 8 7571995-7575006 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA060078 Approved Nucleoplasm,Nucleoli NA NA Nucleoplasm Nucleoli "HPA060078: " FAM90A23 FAM90A23P ENSG00000285765 "Family with sequence similarity 90 member A23" A8MXZ1 8 7579644-7582653 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA060078 Approved Nucleoplasm,Nucleoli NA NA Nucleoplasm Nucleoli "HPA060078: " FAM90A24P FAM90A24 ENSG00000215354 "Family with sequence similarity 90 member A24, pseudogene" P0C7X0 8 8019429-8024652 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 22 "Epicardial cells: 2.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA060078 Approved Nucleoplasm,Nucleoli NA NA "Cluster 9: Non-specific - Receptor signaling" "Cluster 27: Breast cancer - Unknown function" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" Nucleoplasm Nucleoli "HPA060078: " FAM90A26 FAM90A26P ENSG00000229924 "Family with sequence similarity 90 member A26" D6RGX4 4 9170409-9176730 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 5 "Epididymal principal cells: 12.0" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA060078 Approved Nucleoplasm,Nucleoli NA NA "Cluster 32: Cerebral cortex - Mixed function" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" Nucleoplasm Nucleoli "HPA060078: " FAM90A27P ENSG00000189348 "Family with sequence similarity 90 member A27, pseudogene" 19 53277462-53284947 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Early spermatids: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" HPA042086 Uncertain Cytosol NA NA "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" Cytosol "HPA042086: " FAM90A3P FAM90A3 ENSG00000233132 "Family with sequence similarity 90 member A3, pseudogene" 8 7264526-7267536 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA060078 Approved Nucleoplasm,Nucleoli NA NA Nucleoplasm Nucleoli "HPA060078: " FAM90A5P FAM90A5 ENSG00000215373 "Family with sequence similarity 90 member A5, pseudogene" A8MXJ8 8 7287392-7290402 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA060078 Approved Nucleoplasm,Nucleoli NA NA Nucleoplasm Nucleoli "HPA060078: " FAM90A7 FAM90A7P ENSG00000285975 "Family with sequence similarity 90 member A7" A6NKC0 8 7556700-7559712 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA060078 Approved Nucleoplasm,Nucleoli NA NA Nucleoplasm Nucleoli "HPA060078: " FAM90A8 FAM90A8P ENSG00000285937 "Family with sequence similarity 90 member A8" A6NJQ4 8 7738387-7741396 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA060078 Approved Nucleoplasm,Nucleoli NA NA Nucleoplasm Nucleoli "HPA060078: " FAM90A9 FAM90A9P ENSG00000285607 "Family with sequence similarity 90 member A9" A6NNJ1 8 7761330-7764340 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA060078 Approved Nucleoplasm,Nucleoli NA NA Nucleoplasm Nucleoli "HPA060078: " FAM91A1 FLJ23790 ENSG00000176853 "Family with sequence similarity 91 member A1" Q658Y4 8 123768439-123815452 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 257.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027978 Approved Approved Nucleoplasm,Microtubules NA NA 3900 "Cluster 25: Non-specific - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 55: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 26 "Nucleoplasm, Microtubules" "HPA027978: " "unprognostic (4.71e-1)" "unprognostic (2.45e-3)" "unprognostic (4.40e-2)" "unprognostic (3.02e-2)" "unprognostic (6.47e-2)" "unprognostic (1.77e-2)" "unprognostic (3.02e-1)" "unprognostic (1.14e-2)" "unprognostic (1.14e-1)" "unprognostic (6.15e-2)" "unprognostic (1.09e-3)" "unprognostic (6.29e-2)" "unprognostic (1.75e-2)" "unprognostic (4.36e-3)" "unprognostic (1.24e-2)" "potential prognostic unfavorable (7.54e-4)" "unprognostic (3.62e-3)" "unprognostic (1.01e-1)" "unprognostic (7.73e-2)" "unprognostic (1.55e-1)" "unprognostic (2.47e-2)" "unprognostic (1.16e-2)" "potential prognostic unfavorable (5.42e-5)" "unprognostic (1.31e-2)" "unprognostic (6.12e-2)" "unprognostic (2.47e-2)" "unprognostic (2.78e-1)" "unprognostic (8.81e-2)" "unprognostic (2.47e-1)" "unprognostic (7.69e-2)" "unprognostic (1.18e-1)" FAM98A DKFZP564F0522 ENSG00000119812 "Family with sequence similarity 98 member A" Q8NCA5 2 33532744-33599347 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 345.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036250, HPA036251" Uncertain Approved Vesicles NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 27 Vesicles "HPA036250: , HPA036251: " "unprognostic (7.10e-2)" "unprognostic (1.42e-2)" "unprognostic (1.75e-2)" "unprognostic (5.16e-3)" "unprognostic (4.72e-2)" "unprognostic (1.30e-1)" "unprognostic (2.39e-1)" "unprognostic (1.33e-2)" "unprognostic (7.79e-3)" "potential prognostic unfavorable (8.73e-7)" "unprognostic (1.28e-3)" "unprognostic (3.86e-1)" "unprognostic (1.81e-1)" "validated prognostic unfavorable (2.73e-8)" "validated prognostic unfavorable (2.61e-4)" "unprognostic (9.91e-3)" "unprognostic (1.78e-2)" "unprognostic (1.56e-1)" "unprognostic (1.33e-1)" "unprognostic (2.40e-1)" "unprognostic (3.70e-2)" "unprognostic (1.23e-2)" "unprognostic (3.68e-2)" "unprognostic (2.00e-1)" "unprognostic (3.48e-2)" "unprognostic (4.98e-2)" "unprognostic (6.08e-2)" "unprognostic (5.82e-2)" "unprognostic (1.54e-1)" "potential prognostic unfavorable (6.71e-5)" "unprognostic (1.41e-1)" FAM98B FLJ38426 ENSG00000171262 "Family with sequence similarity 98 member B" Q52LJ0 15 38454127-38487710 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 92.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008320, HPA008502" Enhanced Supported Nucleoplasm,Vesicles NA NA 8000 "Cluster 22: Eosinophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 17 "Nucleoplasm, Vesicles" "HPA008320: , HPA008502: " "unprognostic (2.06e-1)" "potential prognostic unfavorable (4.65e-4)" "unprognostic (2.21e-2)" "unprognostic (2.00e-1)" "unprognostic (1.34e-1)" "unprognostic (8.80e-2)" "unprognostic (9.82e-3)" "unprognostic (2.36e-2)" "unprognostic (7.21e-2)" "unprognostic (1.21e-2)" "potential prognostic favorable (5.84e-8)" "unprognostic (3.22e-3)" "unprognostic (5.75e-2)" "unprognostic (6.15e-3)" "unprognostic (8.49e-3)" "potential prognostic unfavorable (8.17e-4)" "unprognostic (1.33e-1)" "unprognostic (9.52e-2)" "unprognostic (9.26e-3)" "unprognostic (3.15e-2)" "unprognostic (1.61e-2)" "unprognostic (6.16e-2)" "unprognostic (7.77e-3)" "unprognostic (9.42e-2)" "unprognostic (8.34e-2)" "unprognostic (1.95e-1)" "unprognostic (8.46e-2)" "unprognostic (1.85e-1)" "unprognostic (3.82e-1)" "unprognostic (9.73e-2)" "unprognostic (5.23e-2)" FAM98C FLJ44669 ENSG00000130244 "Family with sequence similarity 98 member C" Q17RN3 19 38403093-38409088 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 90.2;Esophageal apical cells: 62.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Skeletal muscle - Fibroblasts, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040930, HPA041730" Approved Approved Nucleoplasm,Nucleoli,Cytosol No No "Cluster 45: Eosinophils - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 51: Neurons - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 14 "Nucleoplasm, Nucleoli" Cytosol "HPA040930: , HPA041730: " "unprognostic (3.64e-2)" "unprognostic (1.13e-1)" "unprognostic (3.00e-1)" "unprognostic (1.11e-1)" "unprognostic (2.50e-1)" "unprognostic (1.40e-1)" "unprognostic (2.39e-1)" "unprognostic (2.33e-1)" "unprognostic (8.09e-3)" "unprognostic (1.78e-1)" "potential prognostic favorable (6.12e-6)" "unprognostic (1.86e-1)" "unprognostic (2.53e-2)" "unprognostic (8.55e-2)" "unprognostic (5.56e-2)" "unprognostic (6.04e-2)" "unprognostic (1.65e-1)" "unprognostic (1.09e-1)" "unprognostic (1.15e-1)" "unprognostic (1.53e-3)" "unprognostic (2.30e-2)" "unprognostic (2.27e-1)" "unprognostic (6.87e-2)" "unprognostic (3.02e-2)" "unprognostic (9.81e-2)" "unprognostic (2.38e-1)" "unprognostic (1.11e-1)" "unprognostic (3.32e-3)" "unprognostic (4.24e-2)" "unprognostic (4.40e-2)" "unprognostic (1.38e-1)" FAM9A TEX39A ENSG00000183304 "Family with sequence similarity 9 member A" Q8IZU1 X 8790795-8801383 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 5 "testis: 4.1" "Group enriched" "Detected in some" 4 "Differentiating spermatogonia: 31.1;Early primary spermatocytes: 70.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 1.2;Sarcoma: 1.1" "Testis - Spermatocytes" HPA056076 Uncertain Approved "Mid piece" NA NA "Cluster 47: Testis - Mixed function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 3: Early primary spermatocytes - Early meiosis" 57 "Mid piece" "HPA056076: " FAM9B TEX39B ENSG00000177138 "Family with sequence similarity 9 member B" Q8IZU0 X 9024232-9295682 "Plasma proteins, Predicted intracellular proteins" Meiosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "endometrium 1: 2.0;liver: 3.6;testis: 5.9" "Cell type enhanced" "Detected in some" "Decidual stromal cells: 17.8;Differentiating spermatogonia: 75.6;Early primary spermatocytes: 167.5;Epididymal principal cells: 58.9;Hepatocytes: 19.1;Oocytes: 69.1;Peritubular myoid cells: 17.6;Somatotrophs: 35.7;Undifferentiated spermatogonia: 19.7" "Cell type enhanced" "Detected in many" "medium spiny neuron: 16.7;thalamic excitatory: 31.4" "Cancer enhanced" "Detected in single" "Testicular Germ Cell Tumor (TCGA): 1.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "Myeloma: 5.5;skin cancer: 6.1" "Testis - Spermatocytes" HPA035135 Uncertain Uncertain Nucleoplasm NA NA "Cluster 47: Testis - Mixed function" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 66: Non-specific - Mitochondria" "Cluster 3: Early primary spermatocytes - Early meiosis" 126 Nucleoplasm "HPA035135: " "unprognostic (1.58e-2)" "unprognostic (2.01e-1)" FAM9C TEX39C ENSG00000187268 "Family with sequence similarity 9 member C" Q8IZT9 X 13035617-13044682 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "lymphoid tissue: 35.9" "Cell type enriched" "Detected in some" 10 "Early primary spermatocytes: 125.8" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 15 "Testicular Germ Cell Tumor (TCGA): 21.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 142.1" "Testis - Spermatocytes" NA NA "Cluster 66: Lymphoid tissue - Immune response" "Cluster 14: Neurons - Synaptic function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 3: Early primary spermatocytes - Early meiosis" 15 "unprognostic (3.31e-1)" "unprognostic (2.67e-1)" FAN1 "KIAA1018, MTMR15" ENSG00000198690 "FANCD2 and FANCI associated nuclease 1" Q9Y2M0 15 30890559-30943108 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" "Endonuclease, Exonuclease, Hydrolase, Nuclease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 39.5;Bergmann glia: 42.0;Brain excitatory neurons: 38.5;Brain inhibitory neurons: 36.1;Choroid plexus epithelial cells: 52.8;Distal convoluted tubule cells: 52.3;Ependymal cells: 33.4;Loop of henle epithelial cells: 43.7;Microglia: 33.0;Oligodendrocyte progenitor cells: 40.4;Oligodendrocytes: 63.9;Other brain neurons: 43.0;Proximal tubule cells: 36.1;Renal collecting duct intercalated cells: 40.5;Renal collecting duct principal cells: 32.2;Renal connecting tubule cells: 45.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048198 Approved "Nucleoplasm,Cytokinetic bridge,Primary cilium,Cytosol" Yes NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 64: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 102: Non-specific - Mixed function" 10 "Nucleoplasm, Cytosol" "Cytokinetic bridge, Primary cilium" "HPA048198: " "unprognostic (1.73e-2)" "unprognostic (6.89e-3)" "unprognostic (1.79e-3)" "unprognostic (6.62e-2)" "potential prognostic favorable (2.21e-4)" "unprognostic (1.53e-1)" "unprognostic (4.29e-3)" "unprognostic (6.69e-3)" "unprognostic (2.72e-2)" "potential prognostic favorable (1.23e-4)" "unprognostic (1.19e-1)" "unprognostic (5.50e-2)" "unprognostic (6.61e-2)" "unprognostic (7.83e-2)" "unprognostic (6.62e-2)" "unprognostic (7.06e-2)" "unprognostic (9.56e-3)" "unprognostic (3.66e-1)" "unprognostic (3.48e-3)" "unprognostic (2.16e-1)" "unprognostic (9.33e-3)" "unprognostic (2.25e-2)" "unprognostic (1.24e-1)" "unprognostic (7.57e-3)" "unprognostic (7.67e-3)" "unprognostic (2.70e-1)" "unprognostic (3.19e-1)" "unprognostic (1.40e-1)" "unprognostic (3.02e-1)" "unprognostic (1.09e-1)" FANCA "FA-H, FAA, FACA, FAH, FANCH" ENSG00000187741 "FA complementation group A" O15360 16 89726683-89816977 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 21.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 85.8;Differentiating spermatogonia: 85.2;Early primary spermatocytes: 143.1;Epicardial cells: 95.5;Erythrocyte progenitors: 121.5;Megakaryocyte progenitors: 69.2;Monocyte progenitors: 83.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA063236 Supported Nucleoplasm NA Yes "Cluster 25: Non-specific - Unknown function" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 53: Neurons - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 27: Non-specific - Cell proliferation" 73 Nucleoplasm "HPA063236: " "unprognostic (8.70e-2)" "unprognostic (7.67e-2)" "unprognostic (8.91e-2)" "unprognostic (4.22e-2)" "unprognostic (2.52e-1)" "unprognostic (8.30e-3)" "unprognostic (1.75e-1)" "unprognostic (5.26e-2)" "unprognostic (3.67e-1)" "unprognostic (7.29e-3)" "potential prognostic unfavorable (2.49e-5)" "unprognostic (5.59e-3)" "unprognostic (2.14e-1)" "unprognostic (1.94e-3)" "unprognostic (4.83e-2)" "unprognostic (2.74e-3)" "unprognostic (2.22e-3)" "unprognostic (1.69e-1)" "unprognostic (1.08e-1)" "unprognostic (4.67e-2)" "unprognostic (4.90e-3)" "unprognostic (7.02e-3)" "unprognostic (2.69e-2)" "potential prognostic unfavorable (5.39e-4)" "unprognostic (2.43e-2)" "unprognostic (2.87e-1)" "unprognostic (8.15e-2)" "unprognostic (5.38e-2)" "unprognostic (3.24e-1)" "unprognostic (8.44e-2)" "unprognostic (2.94e-1)" FANCB "FAAP95, FAB, FLJ34064" ENSG00000181544 "FA complementation group B" Q8NB91 X 14690388-14873255 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "Fanconi anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 2.3;lymphoid tissue: 1.7" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 31.4;Erythrocyte progenitors: 97.1;Extravillous trophoblasts: 29.8;Megakaryocyte progenitors: 44.4;Megakaryocyte-Erythroid progenitors: 27.8;Monocyte progenitors: 59.5;Neutrophil progenitors: 46.4;Oligodendrocytes: 34.7;Undifferentiated spermatogonia: 27.4" "Cell type enhanced" "Detected in all" "oligodendrocyte: 44.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA003124 Uncertain NA NA "Cluster 32: Basophils - Transcription" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 27: Non-specific - Cell proliferation" 17 "HPA003124: " "unprognostic (2.82e-1)" "unprognostic (1.17e-1)" "unprognostic (3.15e-1)" "unprognostic (1.33e-1)" "unprognostic (1.45e-1)" "unprognostic (7.35e-3)" "unprognostic (2.18e-1)" "potential prognostic unfavorable (2.66e-4)" "unprognostic (1.02e-2)" "unprognostic (1.79e-1)" FANCC "FA3, FAC, FACC" ENSG00000158169 "FA complementation group C" Q00597 9 95099054-95426796 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 23.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 495.0;Myonuclei: 298.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "basophil: 10.6" "Lineage enriched" "Detected in many" 7 "granulocytes: 10.6" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017793, HPA030771" Approved Supported Nucleoplasm NA NA "Cluster 32: Basophils - Transcription" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 25: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 48 Nucleoplasm "CAB017793: , HPA030771: " "unprognostic (5.57e-2)" "unprognostic (9.37e-3)" "unprognostic (3.00e-1)" "unprognostic (3.23e-2)" "unprognostic (1.33e-1)" "unprognostic (2.17e-1)" "unprognostic (1.82e-1)" "unprognostic (2.74e-2)" "unprognostic (2.76e-2)" "unprognostic (6.34e-2)" "validated prognostic favorable (7.08e-7)" "validated prognostic favorable (2.70e-4)" "unprognostic (8.54e-3)" "unprognostic (1.72e-2)" "unprognostic (7.60e-2)" "unprognostic (4.19e-3)" "unprognostic (4.08e-2)" "unprognostic (6.39e-2)" "unprognostic (1.44e-2)" "unprognostic (1.75e-1)" "unprognostic (8.22e-2)" "unprognostic (6.90e-2)" "unprognostic (1.35e-2)" "unprognostic (1.90e-2)" "unprognostic (1.06e-2)" "unprognostic (1.05e-1)" "unprognostic (2.13e-2)" "unprognostic (5.81e-2)" "unprognostic (3.16e-1)" "unprognostic (2.85e-1)" "unprognostic (1.32e-2)" FANCD2 "FA-D2, FACD, FAD, FANCD" ENSG00000144554 "FA complementation group D2" Q9BXW9 3 10026370-10101932 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 12.8;lymphoid tissue: 10.0" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 59.3;Early primary spermatocytes: 103.7;Erythrocyte progenitors: 90.2;Megakaryocyte progenitors: 69.7;Monocyte progenitors: 72.8;Neutrophil progenitors: 52.6" "Cell type enhanced" "Detected in many" "leukocyte: 15.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Lung - Mitotic cells (Lung), Spleen - B-cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB016117, HPA063742" Approved Supported "Nucleoplasm,Nucleoli,Nuclear bodies,Cytosol" No No "Cluster 32: Basophils - Transcription" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 6: Non-specific - Immune response" "Cluster 34: Testis cancer - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 88 "Nucleoplasm, Nuclear bodies" "Nucleoli, Cytosol" "CAB016117: , HPA063742: " "unprognostic (1.27e-1)" "unprognostic (3.27e-3)" "unprognostic (5.45e-2)" "unprognostic (2.30e-1)" "unprognostic (1.17e-2)" "unprognostic (2.95e-1)" "unprognostic (2.26e-1)" "unprognostic (2.99e-3)" "unprognostic (3.31e-2)" "potential prognostic unfavorable (1.89e-4)" "unprognostic (5.41e-3)" "unprognostic (1.30e-1)" "unprognostic (3.89e-2)" "unprognostic (1.34e-3)" "potential prognostic unfavorable (1.50e-4)" "unprognostic (8.86e-2)" "potential prognostic unfavorable (6.14e-4)" "unprognostic (1.71e-1)" "unprognostic (1.69e-2)" "unprognostic (7.62e-3)" "unprognostic (3.60e-1)" "unprognostic (6.00e-2)" "unprognostic (1.06e-2)" "unprognostic (1.30e-1)" "unprognostic (1.19e-3)" "unprognostic (1.69e-2)" "unprognostic (6.85e-2)" "unprognostic (3.68e-3)" "unprognostic (3.55e-1)" "unprognostic (1.52e-3)" "unprognostic (2.51e-2)" FANCD2OS "C3orf24, MGC40179" ENSG00000163705 "FANCD2 opposite strand" Q96PS1 3 10081317-10108255 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 59 "testis: 58.0" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 66.6;Early spermatids: 664.2;Late primary spermatocytes: 222.0;Late spermatids: 1078.7" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "neutrophil: 5.3" "Lineage enriched" "Detected in many" 5 "granulocytes: 5.3" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA065487 Approved Vesicles NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 23: Testis - Spermatogenesis" "Cluster 15: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 13 Vesicles "HPA065487: " "unprognostic (9.50e-2)" FANCE "FACE, FAE" ENSG00000112039 "FA complementation group E" Q9HB96 6 35452338-35467104 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 25.8;Extravillous trophoblasts: 152.7;Migrating cytotrophoblasts: 28.8;Syncytiotrophoblasts: 61.6" "Cell type enhanced" "Detected in many" "pericyte: 14.5;vascular associated smooth muscle cell: 10.0" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013343, CAB014893" Enhanced Supported "Nucleoplasm,Mitotic chromosome,Centrosome" Yes NA "Cluster 24: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 16 Nucleoplasm "Mitotic chromosome, Centrosome" "CAB014893: , HPA013343: " "unprognostic (2.69e-2)" "unprognostic (1.10e-1)" "unprognostic (1.74e-1)" "unprognostic (1.04e-2)" "unprognostic (1.53e-1)" "unprognostic (5.92e-2)" "unprognostic (2.00e-1)" "unprognostic (9.47e-2)" "unprognostic (1.19e-3)" "unprognostic (1.73e-1)" "unprognostic (4.40e-3)" "unprognostic (1.19e-1)" "unprognostic (1.66e-1)" "validated prognostic unfavorable (1.36e-8)" "validated prognostic unfavorable (1.44e-4)" "unprognostic (5.16e-2)" "unprognostic (2.23e-1)" "unprognostic (1.94e-2)" "unprognostic (1.89e-2)" "unprognostic (2.38e-1)" "unprognostic (6.90e-2)" "unprognostic (1.86e-1)" "unprognostic (2.34e-2)" "unprognostic (4.70e-2)" "unprognostic (7.44e-3)" "unprognostic (2.06e-2)" "unprognostic (6.82e-2)" "unprognostic (8.09e-2)" "unprognostic (2.78e-1)" "unprognostic (5.31e-2)" "unprognostic (1.73e-1)" FANCF FAF ENSG00000183161 "FA complementation group F" Q9NPI8 11 22622533-22625823 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "Cancer-related genes, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 173.2;Late primary spermatocytes: 113.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008899 Supported Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 19 Nucleoplasm "HPA008899: " "unprognostic (2.10e-3)" "unprognostic (6.50e-2)" "unprognostic (1.45e-1)" "unprognostic (1.81e-2)" "unprognostic (9.76e-2)" "unprognostic (1.82e-1)" "unprognostic (1.93e-2)" "unprognostic (1.08e-2)" "unprognostic (9.51e-2)" "unprognostic (6.63e-3)" "unprognostic (5.74e-3)" "unprognostic (3.60e-2)" "unprognostic (1.28e-1)" "unprognostic (1.63e-3)" "unprognostic (1.07e-2)" "unprognostic (3.61e-2)" "unprognostic (3.28e-3)" "unprognostic (2.51e-1)" "unprognostic (3.19e-1)" "unprognostic (1.07e-2)" "unprognostic (7.53e-2)" "unprognostic (1.36e-1)" "unprognostic (2.45e-1)" "unprognostic (3.61e-1)" "potential prognostic favorable (1.00e-4)" "unprognostic (1.63e-1)" "unprognostic (3.24e-1)" "unprognostic (5.05e-2)" "unprognostic (2.23e-1)" "unprognostic (1.64e-1)" "unprognostic (9.22e-2)" FANCG "FAG, XRCC9" ENSG00000221829 "FA complementation group G" O15287 9 35073835-35080004 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 13.2;Early primary spermatocytes: 12.4;Megakaryocyte progenitors: 8.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006695, CAB008105" Approved Supported "Nuclear speckles" NA Yes "Cluster 5: Non-specific - Cell proliferation" "Cluster 49: Non-specific - Transcription" "Cluster 39: Astrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 27: Non-specific - Cell proliferation" 82 "Nuclear speckles" "CAB008105: , HPA006695: " "unprognostic (9.74e-3)" "unprognostic (4.29e-1)" "unprognostic (8.13e-2)" "unprognostic (1.58e-1)" "unprognostic (1.23e-1)" "unprognostic (3.03e-2)" "unprognostic (2.63e-1)" "potential prognostic favorable (2.28e-4)" "unprognostic (1.24e-2)" "unprognostic (8.72e-3)" "potential prognostic favorable (1.17e-5)" "unprognostic (2.71e-1)" "unprognostic (2.13e-1)" "potential prognostic unfavorable (2.30e-4)" "unprognostic (4.40e-3)" "unprognostic (2.75e-2)" "unprognostic (1.35e-3)" "unprognostic (1.44e-1)" "unprognostic (3.61e-2)" "unprognostic (5.90e-2)" "unprognostic (6.74e-3)" "unprognostic (3.49e-1)" "unprognostic (3.54e-2)" "unprognostic (2.33e-1)" "unprognostic (4.25e-2)" "unprognostic (2.99e-2)" "unprognostic (6.55e-2)" "unprognostic (5.32e-2)" "unprognostic (4.19e-2)" "unprognostic (1.10e-1)" "unprognostic (2.03e-1)" FANCI "FLJ10719, KIAA1794" ENSG00000140525 "FA complementation group I" Q9NVI1 15 89243945-89317261 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, DNA damage, DNA repair" DNA-binding "Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 28.0;lymphoid tissue: 41.4;testis: 29.9" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 102.5;Early primary spermatocytes: 179.0;Erythrocyte progenitors: 193.8;Megakaryocyte progenitors: 137.4;Monocyte progenitors: 136.5;Neutrophil progenitors: 109.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 22.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA039972, HPA040379" Approved Enhanced Nucleoplasm NA NA "Cluster 32: Basophils - Transcription" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 37: Neurons - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 27: Non-specific - Cell proliferation" 26 Nucleoplasm "HPA039972: , HPA040379: " "unprognostic (9.23e-2)" "unprognostic (1.00e-2)" "unprognostic (3.59e-1)" "unprognostic (1.91e-1)" "unprognostic (1.78e-1)" "unprognostic (1.78e-1)" "unprognostic (3.98e-1)" "potential prognostic favorable (2.36e-4)" "unprognostic (2.27e-1)" "potential prognostic unfavorable (1.46e-6)" "unprognostic (1.64e-1)" "unprognostic (4.80e-2)" "unprognostic (6.36e-3)" "validated prognostic unfavorable (2.59e-5)" "validated prognostic unfavorable (2.62e-4)" "unprognostic (1.38e-3)" "potential prognostic unfavorable (2.11e-4)" "unprognostic (2.05e-2)" "unprognostic (1.62e-2)" "unprognostic (1.92e-2)" "unprognostic (1.35e-1)" "unprognostic (1.87e-3)" "unprognostic (9.77e-3)" "unprognostic (4.73e-2)" "unprognostic (1.18e-2)" "unprognostic (1.10e-1)" "unprognostic (5.16e-2)" "unprognostic (4.62e-2)" "unprognostic (4.21e-1)" "unprognostic (1.64e-1)" "unprognostic (1.53e-1)" FANCL "FAAP43, FLJ10335, PHF9, Pog" ENSG00000115392 "FA complementation group L" Q9NW38 2 58159243-58241410 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Lactotrophs: 236.5;Oligodendrocytes: 180.3;Somatotrophs: 226.9;Thyrotrophs: 205.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033842, HPA036685, HPA036686" Supported Approved "Nuclear bodies,Vesicles" NA Yes "Cluster 14: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 60 "Nuclear bodies" Vesicles "CAB033842: , HPA036685: , HPA036686: " "unprognostic (4.57e-2)" "unprognostic (2.67e-1)" "unprognostic (3.24e-1)" "unprognostic (8.80e-2)" "unprognostic (8.01e-3)" "unprognostic (4.17e-2)" "unprognostic (8.52e-3)" "unprognostic (6.59e-3)" "unprognostic (6.56e-2)" "unprognostic (2.45e-2)" "unprognostic (1.90e-2)" "unprognostic (1.31e-1)" "unprognostic (3.13e-2)" "potential prognostic unfavorable (1.10e-7)" "unprognostic (1.19e-2)" "potential prognostic unfavorable (2.09e-5)" "unprognostic (7.39e-2)" "unprognostic (1.57e-2)" "unprognostic (1.14e-1)" "unprognostic (4.16e-2)" "unprognostic (1.94e-2)" "unprognostic (1.52e-2)" "unprognostic (4.04e-2)" "unprognostic (9.00e-2)" "unprognostic (2.51e-2)" "unprognostic (2.11e-1)" "unprognostic (1.71e-3)" "unprognostic (4.57e-2)" "unprognostic (1.21e-1)" "unprognostic (9.44e-3)" "unprognostic (2.64e-2)" FANCM "FAAP250, KIAA1596" ENSG00000187790 "FA complementation group M" Q8IYD8 14 45135930-45200890 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Helicase, Hydrolase" "Disease variant, Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 6.5" "Cell type enhanced" "Detected in many" "Early spermatids: 101.8;Late spermatids: 345.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055144 Supported Nucleoplasm NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 39: Testis - Nuclear processes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 31 Nucleoplasm "HPA055144: " "unprognostic (1.12e-1)" "unprognostic (1.86e-2)" "unprognostic (6.90e-2)" "unprognostic (3.73e-2)" "unprognostic (1.90e-1)" "unprognostic (1.47e-1)" "unprognostic (1.95e-1)" "unprognostic (1.99e-3)" "unprognostic (6.66e-3)" "unprognostic (3.39e-2)" "potential prognostic favorable (8.72e-4)" "unprognostic (1.41e-2)" "unprognostic (5.83e-2)" "unprognostic (1.21e-3)" "unprognostic (2.33e-3)" "unprognostic (4.52e-2)" "unprognostic (2.66e-2)" "unprognostic (7.11e-2)" "unprognostic (2.77e-1)" "unprognostic (1.34e-1)" "unprognostic (3.61e-1)" "potential prognostic unfavorable (2.92e-4)" "unprognostic (7.89e-2)" "unprognostic (3.05e-1)" "unprognostic (3.95e-2)" "unprognostic (3.33e-2)" "unprognostic (2.35e-1)" "unprognostic (1.93e-1)" "unprognostic (1.08e-1)" "unprognostic (2.27e-1)" FANK1 ENSG00000203780 "Fibronectin type III and ankyrin repeat domains 1" Q8TC84 10 125896564-126009592 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 64.6;fallopian tube: 32.9;testis: 56.5" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 370.0;Early spermatids: 691.1;Endometrial ciliated cells: 340.5;Ependymal cells: 605.1;Epididymal efferent duct ciliated cells: 369.8;Fallopian tube ciliated cells: 337.9;Late primary spermatocytes: 505.0;Late spermatids: 815.4;Respiratory ciliated cells: 685.5" "Group enriched" "Detected in many" 8 "choroid plexus epithelial cell: 295.4;ependymal cell: 642.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 16 "T-reg: 61.4" "Lineage enriched" "Detected in single" 614 "T-cells: 61.4" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA038413 Supported Nucleoplasm NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 59: Leukemia - T-cell receptor" "Cluster 34: Ciliated cells - Cilia assembly & function" 7 Nucleoplasm "HPA038413: " "unprognostic (1.58e-1)" "unprognostic (3.17e-1)" "unprognostic (3.21e-2)" "unprognostic (8.03e-3)" "unprognostic (1.14e-1)" "unprognostic (4.68e-2)" "unprognostic (2.87e-3)" "unprognostic (6.05e-2)" "unprognostic (3.15e-1)" "unprognostic (3.49e-1)" "unprognostic (3.51e-2)" "unprognostic (1.15e-1)" "unprognostic (1.90e-2)" "unprognostic (3.72e-1)" "unprognostic (3.50e-2)" "unprognostic (1.34e-1)" "unprognostic (9.74e-2)" "unprognostic (4.61e-1)" "unprognostic (1.74e-1)" "unprognostic (3.84e-1)" "unprognostic (1.95e-2)" "unprognostic (1.22e-3)" "unprognostic (6.16e-2)" "unprognostic (1.38e-1)" "unprognostic (1.01e-1)" "unprognostic (9.78e-2)" "unprognostic (1.60e-2)" "unprognostic (1.67e-2)" "unprognostic (1.57e-1)" "unprognostic (1.02e-1)" FAP DPPIV ENSG00000078098 "Fibroblast activation protein alpha" Q12884 2 162170684-162245151 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Apoptosis, Cell adhesion" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 29.4" "Group enriched" "Detected in many" 4 "Decidual stromal cells: 126.0;Endometrial stromal cells: 155.2;Fibro-adipogenic progenitors: 234.0;Fibroblasts: 70.9;Müller glia: 202.8;Pancreatic islet cells: 213.1" "Cell type enhanced" "Detected in many" "astrocyte: 72.9;fibroblast: 61.2;thalamic excitatory: 35.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 27.0" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Minor Salivary Gland - Macrophages, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Testis - Early spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "cerebral cortex: 4.0;hippocampal formation: 3.1" HPA059739 Uncertain "Secreted to blood" "Cell adhesion" NA NA 108000000 58000000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 7 "HPA059739: " "unprognostic (1.86e-1)" "unprognostic (4.33e-2)" "unprognostic (2.94e-2)" "unprognostic (1.54e-2)" "unprognostic (2.92e-2)" "unprognostic (9.41e-2)" "unprognostic (9.99e-3)" "unprognostic (2.73e-2)" "unprognostic (3.00e-3)" "unprognostic (4.78e-2)" "unprognostic (6.91e-2)" "potential prognostic unfavorable (3.63e-6)" "unprognostic (6.90e-3)" "unprognostic (1.21e-1)" "unprognostic (6.19e-2)" "unprognostic (2.15e-2)" "unprognostic (1.62e-2)" "unprognostic (1.07e-2)" "unprognostic (3.70e-3)" "potential prognostic unfavorable (9.40e-5)" "unprognostic (2.33e-2)" "unprognostic (2.05e-2)" "unprognostic (2.48e-1)" "unprognostic (2.23e-1)" "unprognostic (1.31e-3)" "unprognostic (1.21e-1)" "potential prognostic unfavorable (2.77e-4)" "unprognostic (8.85e-3)" "unprognostic (5.06e-2)" "unprognostic (8.35e-2)" FAR1 "FLJ22728, MLSTD2, SDR10E1" ENSG00000197601 "Fatty acyl-CoA reductase 1" Q8WVX9 11 13668668-13732346 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Cataract, Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Foveolar cells: 432.5;Neutrophil progenitors: 670.4;Neutrophils: 682.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017322 Approved Supported Peroxisomes NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 24: Non-specific - Unknown function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 7 Peroxisomes "HPA017322: " "unprognostic (1.68e-1)" "unprognostic (1.80e-2)" "unprognostic (3.20e-2)" "unprognostic (5.27e-2)" "unprognostic (3.26e-2)" "unprognostic (2.87e-1)" "unprognostic (3.43e-2)" "unprognostic (1.06e-1)" "unprognostic (4.97e-1)" "unprognostic (5.15e-3)" "unprognostic (5.09e-2)" "unprognostic (4.31e-3)" "unprognostic (4.19e-2)" "unprognostic (1.80e-1)" "unprognostic (2.48e-1)" "unprognostic (1.44e-1)" "unprognostic (1.09e-1)" "unprognostic (3.45e-1)" "unprognostic (2.21e-1)" "unprognostic (7.11e-3)" "potential prognostic unfavorable (8.60e-4)" "unprognostic (3.02e-2)" "unprognostic (3.41e-3)" "unprognostic (1.71e-2)" "unprognostic (2.53e-3)" "unprognostic (2.23e-1)" "unprognostic (3.40e-1)" "unprognostic (9.98e-2)" "unprognostic (1.32e-1)" "unprognostic (4.10e-2)" "unprognostic (2.50e-1)" FAR2 "FLJ10462, MLSTD1, SDR10E2" ENSG00000064763 "Fatty acyl-CoA reductase 2" Q96K12 12 29149016-29341121 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 18.1;intestine: 21.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 713.9;Microglia: 267.0;Neutrophil progenitors: 903.9;Neutrophils: 523.8;Syncytiotrophoblasts: 641.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 39.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Macrophages, Prostate - Endothelial cells, Skin - Sebaceous gland cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015884 Approved Approved "Nucleoli,Golgi apparatus" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 77: Intestine - Digestion" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 4 "Golgi apparatus" Nucleoli "HPA015884: " "unprognostic (3.42e-2)" "unprognostic (2.24e-1)" "unprognostic (2.74e-1)" "potential prognostic unfavorable (2.19e-4)" "unprognostic (2.99e-2)" "unprognostic (1.57e-1)" "unprognostic (4.94e-1)" "potential prognostic unfavorable (5.91e-4)" "unprognostic (1.64e-1)" "unprognostic (5.17e-2)" "potential prognostic favorable (3.81e-4)" "unprognostic (3.50e-1)" "unprognostic (1.81e-1)" "unprognostic (6.58e-2)" "unprognostic (6.39e-2)" "unprognostic (3.13e-2)" "unprognostic (2.15e-1)" "unprognostic (1.06e-1)" "unprognostic (8.07e-2)" "unprognostic (1.62e-1)" "unprognostic (3.38e-1)" "unprognostic (4.83e-3)" "unprognostic (8.29e-2)" "unprognostic (1.86e-1)" "unprognostic (1.30e-1)" "unprognostic (4.16e-2)" "unprognostic (3.36e-2)" "unprognostic (3.31e-1)" "unprognostic (1.12e-1)" "unprognostic (2.62e-1)" "unprognostic (2.70e-2)" FARP1 "CDEP, GLCC1, MGC87400, PLEKHC2, PPP1R75" ENSG00000152767 "FERM, ARH/RhoGEF and pleckstrin domain protein 1" Q9Y4F1 13 98142562-98455176 "Predicted intracellular proteins" "Developmental protein, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 674.1;Loop of henle epithelial cells: 703.2;Pituitary stem cells: 712.6;Proximal tubule cells: 1116.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000760 Approved Cytosol NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 51: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 88: Proximal tubular cells - Transmembrane transport" 6 Cytosol "HPA000760: " "potential prognostic favorable (1.71e-5)" "unprognostic (3.96e-2)" "unprognostic (8.16e-2)" "unprognostic (4.73e-3)" "unprognostic (1.20e-1)" "unprognostic (1.16e-1)" "unprognostic (8.38e-3)" "unprognostic (2.61e-2)" "unprognostic (2.43e-1)" "potential prognostic unfavorable (5.11e-4)" "potential prognostic favorable (1.47e-5)" "unprognostic (6.21e-3)" "potential prognostic favorable (7.76e-4)" "unprognostic (1.26e-1)" "unprognostic (2.09e-1)" "unprognostic (1.69e-1)" "potential prognostic unfavorable (6.89e-5)" "unprognostic (5.79e-2)" "unprognostic (1.12e-2)" "unprognostic (5.90e-2)" "unprognostic (2.75e-1)" "unprognostic (1.10e-1)" "unprognostic (7.49e-2)" "unprognostic (2.92e-1)" "unprognostic (1.20e-2)" "unprognostic (1.02e-2)" "unprognostic (3.07e-1)" "unprognostic (6.41e-2)" "unprognostic (1.45e-1)" "unprognostic (1.42e-2)" "unprognostic (3.01e-1)" FARP2 "FIR, FRG, KIAA0793, PLEKHC3" ENSG00000006607 "FERM, ARH/RhoGEF and pleckstrin domain protein 2" O94887 2 241356285-241494841 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Melanocytes: 300.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031226, HPA055592" Approved Approved Cytosol NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 21: Testis - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 82: Dendritic cells - Antigen presentation" 11 Cytosol "HPA031226: , HPA055592: " "unprognostic (5.50e-2)" "unprognostic (1.08e-1)" "unprognostic (4.20e-2)" "unprognostic (2.49e-2)" "unprognostic (3.68e-2)" "unprognostic (1.21e-1)" "unprognostic (4.12e-1)" "unprognostic (1.79e-1)" "unprognostic (4.09e-2)" "unprognostic (2.29e-1)" "potential prognostic favorable (1.97e-5)" "unprognostic (3.24e-2)" "unprognostic (8.54e-2)" "unprognostic (7.86e-2)" "unprognostic (1.27e-1)" "unprognostic (5.36e-2)" "unprognostic (5.93e-2)" "unprognostic (9.72e-2)" "unprognostic (1.88e-2)" "unprognostic (4.61e-2)" "unprognostic (2.97e-1)" "unprognostic (8.77e-2)" "unprognostic (6.84e-2)" "unprognostic (9.90e-2)" "unprognostic (2.29e-1)" "unprognostic (7.92e-2)" "unprognostic (1.49e-1)" "unprognostic (3.65e-2)" "unprognostic (4.88e-2)" "unprognostic (6.56e-2)" "unprognostic (1.69e-1)" FARS2 "dJ236A3.1, FARS1, mtPheRS" ENSG00000145982 "Phenylalanyl-tRNA synthetase 2, mitochondrial" O95363 6 5261044-5829192 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Choroid plexus epithelial cells: 890.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018148, HPA028836" Approved NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 7: Non-specific - Transcription" 63 "HPA018148: , HPA028836: " "unprognostic (1.19e-1)" "unprognostic (8.77e-2)" "unprognostic (5.84e-2)" "unprognostic (1.33e-1)" "unprognostic (6.55e-3)" "unprognostic (2.29e-2)" "unprognostic (1.54e-1)" "unprognostic (4.22e-2)" "unprognostic (3.67e-2)" "unprognostic (5.38e-2)" "potential prognostic favorable (1.38e-7)" "unprognostic (2.73e-3)" "potential prognostic favorable (6.98e-4)" "unprognostic (2.78e-2)" "unprognostic (1.29e-1)" "unprognostic (4.10e-3)" "unprognostic (6.08e-2)" "unprognostic (2.19e-1)" "unprognostic (3.69e-1)" "unprognostic (3.38e-2)" "unprognostic (4.16e-2)" "unprognostic (2.91e-1)" "unprognostic (9.96e-2)" "unprognostic (1.16e-1)" "unprognostic (1.21e-2)" "unprognostic (6.21e-2)" "unprognostic (1.15e-1)" "unprognostic (3.23e-2)" "unprognostic (2.99e-1)" "unprognostic (1.43e-2)" "unprognostic (2.20e-1)" FARSA "CML33, FARSL, FARSLA" ENSG00000179115 "Phenylalanyl-tRNA synthetase subunit alpha" Q9Y285 19 12922479-12934037 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 106.6;Syncytiotrophoblasts: 122.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Stomach - Mitotic cells (Stomach), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001911 Enhanced Approved Cytosol NA NA 17000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 1: Neurons - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 21 Cytosol "HPA001911: " "unprognostic (7.94e-2)" "unprognostic (2.71e-2)" "unprognostic (3.92e-2)" "unprognostic (9.88e-3)" "unprognostic (2.29e-1)" "unprognostic (1.18e-1)" "unprognostic (1.21e-1)" "unprognostic (1.65e-2)" "unprognostic (1.14e-1)" "potential prognostic unfavorable (4.54e-4)" "potential prognostic favorable (2.62e-4)" "unprognostic (9.32e-2)" "unprognostic (9.16e-2)" "unprognostic (3.87e-3)" "potential prognostic unfavorable (1.80e-5)" "unprognostic (2.04e-2)" "unprognostic (1.85e-2)" "potential prognostic favorable (5.50e-4)" "unprognostic (5.30e-2)" "unprognostic (4.02e-2)" "unprognostic (1.04e-1)" "unprognostic (9.44e-2)" "unprognostic (2.36e-1)" "potential prognostic unfavorable (4.35e-4)" "unprognostic (1.41e-2)" "unprognostic (1.13e-1)" "unprognostic (8.65e-2)" "unprognostic (8.42e-3)" "unprognostic (3.26e-1)" "unprognostic (1.20e-1)" "unprognostic (2.40e-1)" FARSB "FARSLB, FRSB, PheHB" ENSG00000116120 "Phenylalanyl-tRNA synthetase subunit beta" Q9NSD9 2 222566899-222656092 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Intellectual disability, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 202.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036677, HPA036678, HPA061398" Enhanced Supported Nucleoplasm,Cytosol NA NA 37000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 17: Non-specific - RNA processing" 13 Nucleoplasm Cytosol "HPA036677: , HPA036678: , HPA061398: " "unprognostic (2.77e-1)" "potential prognostic unfavorable (7.22e-4)" "unprognostic (5.38e-2)" "unprognostic (1.12e-1)" "unprognostic (6.31e-2)" "unprognostic (1.73e-2)" "unprognostic (1.45e-1)" "unprognostic (1.79e-1)" "unprognostic (3.35e-2)" "unprognostic (1.26e-3)" "unprognostic (9.96e-2)" "unprognostic (1.03e-1)" "unprognostic (2.14e-3)" "validated prognostic unfavorable (4.60e-13)" "validated prognostic unfavorable (8.30e-9)" "potential prognostic unfavorable (3.39e-4)" "unprognostic (1.28e-2)" "unprognostic (1.72e-2)" "unprognostic (2.80e-1)" "unprognostic (5.27e-2)" "unprognostic (1.40e-1)" "unprognostic (4.19e-3)" "unprognostic (1.79e-1)" "unprognostic (5.16e-2)" "unprognostic (1.76e-1)" "unprognostic (7.68e-3)" "unprognostic (1.08e-1)" "unprognostic (9.18e-2)" "unprognostic (5.39e-2)" "unprognostic (2.09e-1)" "unprognostic (2.36e-1)" FAS "APO-1, APT1, CD95, FAS1, TNFRSF6" ENSG00000026103 "Fas cell surface death receptor" P25445 10 88953813-89029605 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Apoptosis "Calmodulin-binding, Receptor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 93.9;Alveolar cells type 1: 104.1;Epicardial cells: 95.5;Epididymal basal cells: 143.7;Fallopian secretory cells: 108.1;Mesothelial cells: 106.6;Neutrophils: 161.2" "Group enriched" "Detected in many" 4 "astrocyte: 31.2;central nervous system macrophage: 20.9;endothelial cell: 20.1;ependymal cell: 26.1;fibroblast: 29.7;leukocyte: 33.9;pericyte: 33.9;vascular associated smooth muscle cell: 21.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 101.1" "Group enriched" "Detected in all" 5 "granulocytes: 101.1;T-cells: 90.6" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027444 Uncertain Supported "Nuclear bodies,Plasma membrane,Cytosol" "Secreted to blood" Receptor NA NA 11900000 560000 "Cluster 35: Neutrophils - Protein binding" "Cluster 49: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 9: T-cells - Adaptive immunity: Regulation" 34 "Plasma membrane" "Nuclear bodies, Cytosol" "HPA027444: " "unprognostic (4.87e-2)" "unprognostic (4.15e-2)" "unprognostic (3.99e-2)" "unprognostic (1.23e-1)" "unprognostic (4.12e-3)" "unprognostic (4.53e-2)" "unprognostic (1.05e-2)" "potential prognostic unfavorable (6.97e-4)" "unprognostic (1.90e-1)" "unprognostic (2.22e-1)" "potential prognostic favorable (1.96e-5)" "unprognostic (1.11e-1)" "unprognostic (2.77e-1)" "unprognostic (1.16e-1)" "unprognostic (2.03e-3)" "unprognostic (4.06e-2)" "unprognostic (1.60e-2)" "unprognostic (6.50e-2)" "unprognostic (4.36e-3)" "unprognostic (6.94e-3)" "unprognostic (6.86e-2)" "potential prognostic unfavorable (1.39e-4)" "unprognostic (1.20e-1)" "unprognostic (3.30e-1)" "unprognostic (1.44e-1)" "unprognostic (2.14e-1)" "unprognostic (2.38e-1)" "unprognostic (1.96e-1)" "unprognostic (2.98e-2)" "unprognostic (5.49e-2)" "unprognostic (3.10e-1)" FASLG "APT1LG1, CD178, FasL, TNFSF6" ENSG00000117560 "Fas ligand" P48023 1 172659103-172666876 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins, Transporters" "Apoptosis, Transcription, Transcription regulation" "Cytokine, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 5.3" "Group enriched" "Detected in some" 11 "NK-cells: 52.7;T-cells: 25.0" "Cell type enriched" "Detected in single" 90 "leukocyte: 39.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "gdT-cell: 58.2" "Group enriched" "Detected in many" 9 "NK-cells: 41.6;T-cells: 58.2" "Cancer enriched" "Detected in single" 4 "colorectal cancer: 1.3" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - NK-cells (Liver), Minor Salivary Gland - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Spleen - T-cells, Stomach - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA054959 Approved "Secreted to blood" Cytokine NA NA 73600 "Cluster 15: NK-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 9: Non-specific - Receptor signaling" "Cluster 32: Non-specific - Cell proliferation" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 62 "HPA054959: " "unprognostic (9.66e-3)" "unprognostic (1.11e-1)" "unprognostic (3.36e-3)" "unprognostic (4.01e-2)" "unprognostic (1.76e-3)" "unprognostic (8.66e-2)" "unprognostic (1.80e-1)" "potential prognostic favorable (7.12e-4)" "unprognostic (8.23e-3)" "unprognostic (2.44e-1)" "unprognostic (1.28e-1)" "unprognostic (1.07e-2)" "unprognostic (2.64e-1)" "unprognostic (1.40e-1)" "unprognostic (3.34e-2)" "unprognostic (1.03e-1)" FASN "FAS, SDR27X1" ENSG00000169710 "Fatty acid synthase" P49327 17 82078338-82098294 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Hydrolase, Lyase, Multifunctional enzyme, Oxidoreductase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 364.3;breast: 270.5;liver: 192.6" "Cell type enriched" "Detected in many" 4 "Breast lactating cells: 3382.5" "Cell type enhanced" "Detected in all" "cerebellar inhibitory: 93.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Lung - Alveolar cells type 2, Pituitary gland - Corticotropes, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005192, HPA006461, CAB015417, HPA056108" Enhanced Enhanced "Plasma membrane,Cytosol" No No 3300000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 6: Non-specific - Immune response" "Cluster 27: Breast cancer - Unknown function" "Cluster 4: Breast lactating luminal cells - Lactation" 60 "Plasma membrane, Cytosol" "CAB005192: , CAB015417: , HPA006461: , HPA056108: " "unprognostic (2.78e-2)" "unprognostic (6.23e-2)" "unprognostic (8.08e-2)" "potential prognostic unfavorable (8.58e-6)" "unprognostic (6.36e-2)" "unprognostic (8.71e-2)" "unprognostic (4.76e-2)" "unprognostic (1.46e-1)" "unprognostic (5.38e-2)" "unprognostic (7.40e-3)" "potential prognostic unfavorable (2.84e-4)" "unprognostic (8.13e-3)" "potential prognostic unfavorable (3.88e-4)" "unprognostic (3.83e-2)" "unprognostic (2.13e-1)" "unprognostic (1.89e-1)" "unprognostic (1.90e-2)" "unprognostic (1.11e-2)" "unprognostic (1.98e-2)" "unprognostic (1.51e-1)" "unprognostic (4.17e-3)" "unprognostic (7.36e-2)" "unprognostic (1.94e-1)" "unprognostic (1.70e-1)" "unprognostic (7.55e-2)" "unprognostic (7.18e-2)" "unprognostic (8.07e-2)" "unprognostic (5.28e-2)" "unprognostic (2.00e-1)" "unprognostic (1.73e-2)" "unprognostic (5.37e-2)" FASTK FAST ENSG00000164896 "Fas activated serine/threonine kinase" Q14296 7 151076624-151080866 "Enzymes, Predicted intracellular proteins" Apoptosis "Kinase, RNA-binding, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031621, CAB032539" Approved Supported "Nuclear speckles,Mitochondria" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 85: Squamous epithelial cells - Keratinization" 7 Mitochondria "Nuclear speckles" "CAB032539: , HPA031621: " "unprognostic (2.82e-1)" "unprognostic (1.76e-1)" "unprognostic (2.24e-2)" "unprognostic (1.10e-1)" "unprognostic (5.36e-2)" "unprognostic (7.06e-2)" "unprognostic (7.55e-3)" "unprognostic (1.92e-1)" "unprognostic (6.39e-2)" "unprognostic (2.02e-3)" "unprognostic (1.14e-3)" "unprognostic (9.77e-2)" "unprognostic (2.02e-2)" "unprognostic (9.21e-3)" "unprognostic (9.85e-3)" "unprognostic (1.47e-2)" "unprognostic (2.74e-3)" "unprognostic (2.97e-3)" "unprognostic (2.28e-1)" "unprognostic (2.89e-2)" "unprognostic (1.89e-1)" "unprognostic (1.27e-3)" "unprognostic (1.80e-1)" "unprognostic (8.33e-2)" "unprognostic (5.81e-3)" "unprognostic (2.42e-1)" "unprognostic (5.33e-2)" "unprognostic (1.88e-2)" "unprognostic (6.34e-2)" "unprognostic (2.41e-2)" "unprognostic (1.71e-1)" FASTKD1 FLJ21901 ENSG00000138399 "FAST kinase domains 1" Q53R41 2 169528508-169573875 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 213.1;Myonuclei: 172.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043719 Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 32: Basophils - Transcription" "Cluster 52: Non-specific - Cellular respiration" "Cluster 5: Non-specific - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 42 Mitochondria Nucleoplasm "HPA043719: " "unprognostic (1.51e-1)" "unprognostic (4.33e-3)" "unprognostic (4.09e-1)" "unprognostic (6.45e-2)" "unprognostic (4.24e-2)" "unprognostic (6.45e-3)" "unprognostic (9.83e-2)" "unprognostic (5.14e-2)" "unprognostic (5.62e-2)" "unprognostic (4.26e-3)" "unprognostic (1.79e-3)" "unprognostic (6.51e-3)" "unprognostic (4.56e-2)" "unprognostic (7.34e-3)" "unprognostic (1.14e-1)" "unprognostic (1.26e-1)" "unprognostic (2.57e-1)" "unprognostic (1.32e-1)" "unprognostic (1.97e-1)" "unprognostic (1.07e-2)" "unprognostic (1.10e-1)" "unprognostic (2.18e-1)" "unprognostic (1.27e-2)" "unprognostic (7.99e-2)" "unprognostic (6.71e-3)" "unprognostic (2.95e-1)" "unprognostic (5.74e-3)" "unprognostic (6.22e-2)" "unprognostic (1.39e-1)" "unprognostic (7.01e-2)" "unprognostic (3.67e-2)" FASTKD2 KIAA0971 ENSG00000118246 "FAST kinase domains 2" Q9NYY8 2 206765357-206796189 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ribosome biogenesis" "RNA-binding, rRNA-binding" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067191 Supported Mitochondria NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 76: Non-specific - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 17: Non-specific - RNA processing" 23 Mitochondria "HPA067191: " "unprognostic (2.23e-1)" "unprognostic (5.47e-2)" "unprognostic (1.93e-1)" "unprognostic (1.32e-2)" "potential prognostic favorable (1.27e-4)" "unprognostic (1.63e-2)" "unprognostic (1.25e-1)" "unprognostic (5.44e-2)" "unprognostic (2.45e-2)" "unprognostic (4.84e-3)" "potential prognostic favorable (9.57e-9)" "unprognostic (5.11e-3)" "unprognostic (2.18e-1)" "potential prognostic unfavorable (7.87e-4)" "unprognostic (5.33e-2)" "unprognostic (3.55e-3)" "unprognostic (6.72e-2)" "unprognostic (6.98e-2)" "unprognostic (1.97e-1)" "unprognostic (2.26e-1)" "unprognostic (3.61e-1)" "unprognostic (1.73e-3)" "unprognostic (3.21e-2)" "unprognostic (6.63e-2)" "unprognostic (6.54e-3)" "unprognostic (3.11e-2)" "unprognostic (1.53e-2)" "unprognostic (1.37e-1)" "unprognostic (3.49e-1)" "unprognostic (1.34e-2)" "unprognostic (7.98e-2)" FASTKD3 "FLJ23274, MGC5297" ENSG00000124279 "FAST kinase domains 3" Q14CZ7 5 7859159-7869037 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA068525, HPA074462" Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 76: Non-specific - Metabolism" "Cluster 31: Non-specific - Transcription" "Cluster 29: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 7 "Nucleoplasm, Mitochondria" "HPA068525: , HPA074462: " "unprognostic (1.99e-2)" "unprognostic (2.16e-3)" "unprognostic (6.62e-2)" "unprognostic (2.07e-1)" "unprognostic (3.07e-2)" "unprognostic (6.56e-2)" "unprognostic (7.63e-2)" "unprognostic (1.90e-3)" "unprognostic (3.79e-2)" "unprognostic (9.71e-2)" "potential prognostic favorable (2.52e-5)" "unprognostic (2.38e-1)" "unprognostic (2.97e-1)" "potential prognostic unfavorable (1.35e-4)" "unprognostic (3.04e-2)" "unprognostic (2.80e-1)" "unprognostic (2.44e-2)" "unprognostic (9.72e-2)" "unprognostic (3.63e-2)" "unprognostic (1.61e-1)" "unprognostic (1.21e-1)" "unprognostic (9.12e-2)" "unprognostic (8.04e-2)" "unprognostic (1.33e-2)" "potential prognostic favorable (7.86e-6)" "unprognostic (2.19e-1)" "unprognostic (2.77e-2)" "unprognostic (5.04e-2)" "unprognostic (2.56e-1)" "unprognostic (6.44e-2)" "unprognostic (1.49e-2)" FASTKD5 FLJ13149 ENSG00000215251 "FAST kinase domains 5" Q7L8L6 20 3146519-3159865 "Predicted intracellular proteins" "mRNA processing" "RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Megakaryocytes: 12.4;Paneth cells: 3.9;Platelets: 5.6;Thymic myoid cells: 4.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043833 Approved NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 47: Platelets - Hemostasis" 28 "HPA043833: " "unprognostic (6.71e-2)" "unprognostic (6.59e-2)" "unprognostic (2.36e-1)" "unprognostic (8.04e-2)" "unprognostic (9.50e-2)" "unprognostic (9.07e-2)" "unprognostic (3.12e-1)" "unprognostic (1.38e-1)" "unprognostic (1.58e-1)" "unprognostic (2.20e-1)" "validated prognostic favorable (6.66e-8)" "validated prognostic favorable (7.89e-4)" "unprognostic (3.79e-3)" "potential prognostic unfavorable (1.66e-4)" "unprognostic (1.01e-1)" "unprognostic (5.43e-2)" "unprognostic (8.79e-2)" "unprognostic (1.01e-1)" "unprognostic (7.10e-2)" "unprognostic (5.89e-2)" "unprognostic (2.66e-1)" "unprognostic (3.19e-1)" "unprognostic (9.47e-2)" "unprognostic (1.57e-1)" "unprognostic (2.61e-2)" "unprognostic (1.31e-1)" "unprognostic (4.44e-1)" "unprognostic (3.94e-1)" "unprognostic (5.45e-1)" "unprognostic (6.91e-2)" "unprognostic (3.38e-1)" FAT1 "CDHF7, CDHR8, FAT" ENSG00000083857 "FAT atypical cadherin 1" Q14517 4 186587794-186726722 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 81.8" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 475.6;Endometrial secretory cells: 326.4;Epicardial cells: 327.5;Ocular epithelial cells: 378.4;Podocytes: 523.9;Somatotrophs: 367.7;Urothelial cells: 462.6" "Cell type enhanced" "Detected in many" "Bergmann glia: 261.4;choroid plexus epithelial cell: 432.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Breast myoepithelial cells, Minor Salivary Gland - Smooth muscle cells, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "HPA001869, HPA023882" Enhanced "Intracellular and membrane" "Cell adhesion" NA NA 12000000 "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 44: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 100: Stratified epithelial cells - Barrier functions" 5 "HPA001869: , HPA023882: " "unprognostic (7.54e-2)" "unprognostic (1.84e-1)" "unprognostic (2.02e-1)" "unprognostic (4.81e-3)" "unprognostic (1.67e-1)" "unprognostic (1.35e-1)" "unprognostic (1.72e-1)" "unprognostic (2.28e-1)" "unprognostic (3.33e-2)" "unprognostic (1.16e-1)" "potential prognostic favorable (3.84e-4)" "unprognostic (7.02e-2)" "unprognostic (2.21e-2)" "unprognostic (2.34e-1)" "unprognostic (2.47e-3)" "unprognostic (4.09e-3)" "unprognostic (1.21e-1)" "unprognostic (5.58e-2)" "unprognostic (1.28e-1)" "unprognostic (3.81e-2)" "unprognostic (1.39e-1)" "unprognostic (2.12e-3)" "unprognostic (8.65e-2)" "unprognostic (9.32e-2)" "unprognostic (6.19e-2)" "unprognostic (2.44e-3)" "unprognostic (2.76e-1)" "unprognostic (3.30e-2)" "unprognostic (9.37e-2)" "unprognostic (3.04e-3)" "unprognostic (7.98e-2)" FAT2 "CDHF8, CDHR9, HFAT2, MEGF1" ENSG00000086570 "FAT atypical cadherin 2" Q9NYQ8 5 151504092-151591331 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 223.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 86.8;Basal prostatic cells: 55.9;Brain excitatory neurons: 110.4;Esophageal basal cells: 54.0;Esophageal suprabasal cells: 76.1;Ocular epithelial cells: 123.9;Papillary tip epithelial cells: 53.8;Prostatic hillock cells: 85.1;Respiratory basal cells: 108.1;Suprabasal keratinocytes: 110.2" "Cell type enriched" "Detected in many" 6 "upper rhombic lip: 379.8" "Group enriched" "Detected in many" 9 "Bladder Urothelial Carcinoma (TCGA): 21.5;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 50.3;Head and Neck Squamous Cell Carcinoma (TCGA): 53.2;Lung Squamous Cell Carcinoma (TCGA): 29.1" "Region enriched" "Detected in all" 6 "cerebellum: 234.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Esophageal cancer: 27.8;Gallbladder cancer: 40.3;head and neck cancer: 50.9" "Minor Salivary Gland - Minor salivary gland basal cells, Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in some" 18 "cerebellum: 32.0" "Region enriched" "Detected in many" 58 "cerebellum: 313.3" "CAB033680, HPA044656" Enhanced Uncertain Vesicles NA NA 250000 "Cluster 71: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 2: Cerebellar granular cells - Neuronal signaling" Vesicles "CAB033680: , HPA044656: " "unprognostic (9.23e-2)" "unprognostic (3.94e-3)" "unprognostic (8.91e-2)" "unprognostic (8.74e-2)" "unprognostic (3.66e-1)" "unprognostic (1.81e-1)" "unprognostic (1.10e-1)" "unprognostic (1.54e-1)" "unprognostic (2.62e-1)" "unprognostic (1.48e-1)" "unprognostic (4.65e-3)" "unprognostic (8.55e-2)" "unprognostic (1.10e-1)" "unprognostic (4.51e-1)" FAT3 "CDHF15, CDHR10, KIAA1989" ENSG00000165323 "FAT atypical cadherin 3" Q8TDW7 11 92224818-92896473 "Predicted membrane proteins" "Cell adhesion" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "blood vessel: 5.3;brain: 13.6" "Cell type enhanced" "Detected in many" "Astrocytes: 659.4;Bergmann glia: 1132.1;Brain excitatory neurons: 345.5;Brain inhibitory neurons: 813.2;Ependymal cells: 463.6;Pituicytes/FSCs: 2681.6;Retinal amacrine cells: 431.4;Salivary ionocytes: 431.4" "Cell type enhanced" "Detected in all" "mammillary body: 2248.0" "Cancer enriched" "Detected in single" 8 "Glioblastoma Multiforme (TCGA): 5.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Smooth muscle cells, Heart muscle - Smooth muscle cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Minor Salivary Gland - Minor salivary gland ductal cells, Prostate - Smooth muscle cells, Spleen - Smooth muscle cells, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026878, HPA074824" Uncertain Approved "Cell Junctions" NA NA 210000 "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 1 "Cell Junctions" "HPA026878: , HPA074824: " "unprognostic (7.95e-2)" "unprognostic (1.27e-1)" "unprognostic (5.48e-2)" "unprognostic (2.08e-3)" FAT4 "CDHF14, CDHR11, FAT-J" ENSG00000196159 "FAT atypical cadherin 4" Q6V0I7 4 125314918-125492932 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes, Deafness, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibro-adipogenic progenitors: 192.8;Fibroblasts: 93.9;Hepatic stellate cells: 64.5;Lymphatic endothelial cells: 93.3;Oligodendrocytes: 82.1;Podocytes: 54.2;Renal connecting tubule cells: 66.3;Thyrotrophs: 65.5;Vascular endothelial cells: 138.6" "Cell type enhanced" "Detected in many" "endothelial cell: 195.4;fibroblast: 165.0;hippocampal dentate gyrus: 225.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 18.4" "Breast - Fibroblasts, Prostate - Fibroblasts, Spleen - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA052819 Approved Approved Cytosol NA NA 2500000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 1 Cytosol "HPA052819: " "unprognostic (2.20e-1)" "unprognostic (3.15e-1)" "unprognostic (3.85e-1)" "unprognostic (6.33e-2)" "unprognostic (2.27e-1)" "unprognostic (8.31e-2)" "validated prognostic favorable (2.56e-8)" "validated prognostic favorable (3.00e-5)" "unprognostic (2.98e-2)" "unprognostic (1.70e-3)" "unprognostic (1.57e-1)" "unprognostic (6.75e-2)" "unprognostic (3.54e-1)" "unprognostic (1.92e-1)" "unprognostic (4.29e-2)" "unprognostic (9.58e-2)" "unprognostic (1.45e-1)" "unprognostic (4.77e-2)" "unprognostic (3.93e-2)" "unprognostic (2.68e-1)" "unprognostic (6.78e-3)" FATE1 "CT43, FATE" ENSG00000147378 "Fetal and adult testis expressed 1" Q969F0 X 151716035-151723194 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 107 "testis: 232.5" "Group enriched" "Detected in some" 7 "Late spermatids: 96.6;Sertoli cells: 311.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "Kidney Renal Clear Cell Carcinoma (TCGA): 3.1;Testicular Germ Cell Tumor (TCGA): 9.3" "Region enhanced" "Detected in single" "cerebral cortex: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Sertoli cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA034604 Enhanced NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 53: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 80 "HPA034604: " "unprognostic (2.10e-1)" "validated prognostic favorable (1.05e-6)" "validated prognostic favorable (1.30e-4)" "unprognostic (1.20e-1)" FAU "asr1, FLJ22986, Fub1, Fubi, MNSFbeta, RPS30, S30" ENSG00000149806 "FAU ubiquitin like and ribosomal protein S30 fusion" P62861 11 65120630-65122177 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059015 Supported Enhanced "Nucleoli,Endoplasmic reticulum,Cytosol" No No "Cluster 18: Non-specific - Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 64 "Endoplasmic reticulum, Cytosol" Nucleoli "HPA059015: " "unprognostic (3.79e-3)" "unprognostic (3.32e-3)" "unprognostic (9.15e-2)" "unprognostic (2.20e-2)" "unprognostic (1.12e-1)" "unprognostic (3.34e-2)" "unprognostic (9.78e-2)" "unprognostic (2.28e-2)" "potential prognostic unfavorable (7.43e-4)" "unprognostic (2.82e-1)" "unprognostic (3.28e-1)" "unprognostic (2.77e-1)" "unprognostic (4.35e-2)" "unprognostic (4.87e-2)" "unprognostic (1.09e-2)" "unprognostic (2.16e-1)" "unprognostic (4.48e-3)" "unprognostic (2.65e-1)" "unprognostic (1.90e-2)" "unprognostic (1.11e-2)" "unprognostic (2.31e-1)" "unprognostic (3.58e-2)" "unprognostic (4.02e-1)" "unprognostic (1.46e-1)" "unprognostic (2.12e-1)" "unprognostic (6.99e-2)" "unprognostic (1.11e-1)" "unprognostic (2.09e-1)" "unprognostic (8.54e-2)" "unprognostic (9.04e-2)" "unprognostic (7.39e-2)" FAXC "C6orf168, dJ273F20, MGC2817" ENSG00000146267 "Failed axon connections homolog, metaxin like GST domain containing" Q5TGI0 6 99271168-99350062 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 21.7" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 71.9;Brain inhibitory neurons: 81.1;Corticotrophs: 58.9;Gonadotrophs: 83.9;Lactotrophs: 59.0;Oligodendrocyte progenitor cells: 61.0;Other brain neurons: 57.4;Pituicytes/FSCs: 81.1;Retinal amacrine cells: 57.0;Somatotrophs: 98.7;Thyrotrophs: 68.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Prostate - Smooth muscle cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" HPA039106 Uncertain Approved Nucleoplasm NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 50: Lymphoma - Unknown function" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 13 Nucleoplasm "HPA039106: " "unprognostic (1.40e-2)" "unprognostic (8.91e-2)" "unprognostic (4.47e-3)" "unprognostic (1.49e-2)" "unprognostic (3.65e-1)" "unprognostic (3.55e-1)" "potential prognostic favorable (9.18e-4)" "unprognostic (1.71e-2)" "unprognostic (1.64e-1)" "unprognostic (4.72e-1)" "unprognostic (3.63e-2)" "unprognostic (1.52e-1)" "unprognostic (1.19e-2)" "unprognostic (5.26e-3)" "unprognostic (1.95e-2)" "unprognostic (3.37e-1)" "potential prognostic favorable (8.71e-4)" "unprognostic (3.86e-3)" "unprognostic (1.25e-1)" "unprognostic (9.63e-2)" "unprognostic (6.07e-3)" "unprognostic (4.25e-2)" "unprognostic (2.80e-2)" "unprognostic (1.32e-1)" "unprognostic (3.79e-2)" "unprognostic (4.63e-3)" FAXDC2 "C5orf4, FLJ13758" ENSG00000170271 "Fatty acid hydroxylase domain containing 2" Q96IV6 5 154818492-154859252 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 286.7" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 169.5;Oligodendrocytes: 245.1;Platelets: 708.0" "Cell type enhanced" "Detected in all" "endothelial cell: 244.8;oligodendrocyte: 291.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Kidney - Fibroblasts, Liver - Hepatocytes, Skeletal muscle - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 47: Leukemia - Hemostasis" "Cluster 47: Platelets - Hemostasis" 28 "unprognostic (3.38e-2)" "unprognostic (9.66e-3)" "unprognostic (4.36e-1)" "unprognostic (8.13e-2)" "unprognostic (1.12e-1)" "unprognostic (4.67e-2)" "unprognostic (4.20e-1)" "unprognostic (3.52e-2)" "unprognostic (4.91e-2)" "validated prognostic favorable (5.11e-7)" "validated prognostic favorable (1.58e-5)" "potential prognostic favorable (1.19e-4)" "potential prognostic favorable (9.03e-4)" "unprognostic (5.01e-2)" "unprognostic (4.75e-3)" "unprognostic (1.10e-1)" "unprognostic (1.02e-1)" "unprognostic (9.59e-2)" "unprognostic (9.07e-2)" "unprognostic (3.02e-1)" "unprognostic (1.64e-1)" "unprognostic (8.78e-2)" "unprognostic (1.30e-1)" "unprognostic (2.08e-1)" "unprognostic (8.47e-2)" "unprognostic (4.98e-2)" "unprognostic (3.69e-1)" "potential prognostic unfavorable (3.59e-4)" "unprognostic (6.91e-2)" FBF1 "ALB, FBF-1, FLJ00103, KIAA1863" ENSG00000188878 "Fas binding factor 1" Q8TES7 17 75909574-75941140 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 29.7" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 52.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023677 Supported "Primary cilium,Centrosome,Basal body" NA NA "Cluster 47: Testis - Mixed function" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 65: Non-specific - Cell growth & division" 8 "Centrosome, Basal body" "Primary cilium" "HPA023677: " "unprognostic (1.56e-1)" "unprognostic (1.12e-1)" "potential prognostic favorable (5.00e-4)" "unprognostic (1.80e-1)" "unprognostic (1.69e-1)" "unprognostic (3.24e-2)" "unprognostic (2.15e-2)" "unprognostic (1.32e-1)" "unprognostic (1.28e-3)" "unprognostic (2.07e-2)" "potential prognostic unfavorable (3.87e-8)" "unprognostic (5.04e-3)" "unprognostic (1.64e-1)" "unprognostic (2.02e-3)" "unprognostic (3.59e-2)" "unprognostic (2.87e-1)" "unprognostic (5.40e-3)" "unprognostic (1.17e-1)" "unprognostic (1.76e-2)" "unprognostic (1.90e-2)" "unprognostic (8.25e-3)" "potential prognostic favorable (1.56e-4)" "unprognostic (1.36e-1)" "unprognostic (3.86e-1)" "unprognostic (1.61e-2)" "unprognostic (3.99e-3)" "unprognostic (2.14e-1)" "unprognostic (1.54e-1)" "unprognostic (7.05e-2)" "unprognostic (1.78e-1)" "unprognostic (2.43e-1)" FBH1 "Fbx18, FBXO18, FLJ14590" ENSG00000134452 "F-box DNA helicase 1" Q8NFZ0 10 5890203-5937594 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "DNA-binding, Helicase, Hydrolase, Isomerase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002844 Supported NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 35: Non-specific - Mixed function" "Cluster 36: Choroid plexus - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 44: Plasma cells - Antibody production & secretion" 13 "HPA002844: " "unprognostic (1.20e-1)" "unprognostic (7.96e-3)" "unprognostic (1.97e-1)" "unprognostic (3.35e-2)" "unprognostic (1.48e-1)" "unprognostic (4.88e-2)" "potential prognostic favorable (1.05e-6)" "unprognostic (5.85e-2)" "unprognostic (2.31e-2)" "potential prognostic favorable (1.25e-4)" "unprognostic (8.33e-2)" "unprognostic (3.13e-1)" "potential prognostic unfavorable (2.54e-5)" "unprognostic (2.35e-1)" "unprognostic (1.82e-1)" "unprognostic (2.63e-1)" "unprognostic (4.13e-1)" "unprognostic (4.24e-2)" "unprognostic (1.29e-2)" "unprognostic (1.42e-2)" "unprognostic (2.34e-2)" "unprognostic (1.28e-1)" "unprognostic (1.34e-1)" "unprognostic (9.04e-2)" "unprognostic (7.80e-2)" "unprognostic (5.35e-2)" "unprognostic (9.78e-2)" "unprognostic (4.93e-2)" "unprognostic (2.15e-2)" FBL "FIB, FLRN, Nop1, RNU3IP1" ENSG00000105202 Fibrillarin P22087 19 39834458-39846379 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "rRNA processing" "Methyltransferase, Ribonucleoprotein, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 401.8;Esophageal basal cells: 376.8;Extravillous trophoblasts: 280.5;Late spermatids: 855.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001514, HPA049546, HPA077724" Supported Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA 42000 "Cluster 24: Non-specific - Transcription" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 4: Non-specific - Transcription" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 231 "Nucleoli fibrillar center" Nucleoplasm "CAB001514: , HPA049546: , HPA077724: " "unprognostic (8.95e-2)" "unprognostic (3.14e-3)" "unprognostic (1.47e-1)" "unprognostic (8.77e-2)" "unprognostic (7.18e-2)" "unprognostic (3.12e-1)" "unprognostic (1.89e-3)" "unprognostic (6.83e-2)" "unprognostic (1.66e-1)" "unprognostic (4.31e-1)" "potential prognostic favorable (7.09e-4)" "unprognostic (4.27e-2)" "unprognostic (4.14e-2)" "validated prognostic unfavorable (6.00e-6)" "validated prognostic unfavorable (5.45e-7)" "unprognostic (7.98e-3)" "unprognostic (1.09e-3)" "unprognostic (5.64e-2)" "unprognostic (2.33e-1)" "unprognostic (7.71e-2)" "unprognostic (3.47e-3)" "unprognostic (9.91e-3)" "unprognostic (1.23e-1)" "unprognostic (1.39e-1)" "unprognostic (3.00e-3)" "unprognostic (1.15e-1)" "unprognostic (9.57e-2)" "unprognostic (3.81e-1)" "unprognostic (2.26e-1)" "unprognostic (1.47e-1)" "unprognostic (2.04e-1)" FBLIM1 "CAL, FBLP-1, migfilin" ENSG00000162458 "Filamin binding LIM protein 1" Q8WUP2 1 15756607-15786594 "Essential proteins, Predicted intracellular proteins" "Cell adhesion, Cell shape" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "blood vessel: 444.4" "Cell type enhanced" "Detected in many" "Colonocytes: 241.1;Decidual stromal cells: 123.1;Enterocytes: 268.0;Extravillous trophoblasts: 196.9;Foveolar cells: 228.4;Ocular epithelial cells: 180.7;Pericytes: 116.9;Peritubular myoid cells: 235.4" "Cell type enriched" "Detected in many" 4 "vascular associated smooth muscle cell: 64.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.5" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Fibroblasts, Lung - Smooth muscle cells, Minor Salivary Gland - Minor salivary glandular cells, Spleen - Fibroblasts_1, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA025287, HPA072750" Approved Enhanced "Nucleoli fibrillar center,Cell Junctions,Focal adhesion sites" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 23 "Cell Junctions, Focal adhesion sites" "Nucleoli fibrillar center" "HPA025287: , HPA072750: " "unprognostic (5.39e-2)" "unprognostic (1.25e-1)" "unprognostic (3.36e-1)" "unprognostic (3.68e-3)" "unprognostic (2.57e-1)" "unprognostic (1.38e-1)" "unprognostic (3.87e-2)" "unprognostic (1.13e-1)" "unprognostic (6.11e-2)" "unprognostic (1.17e-2)" "unprognostic (2.58e-1)" "unprognostic (6.62e-2)" "unprognostic (4.27e-2)" "unprognostic (6.08e-2)" "unprognostic (2.31e-2)" "unprognostic (4.52e-2)" "unprognostic (1.85e-2)" "unprognostic (6.92e-3)" "potential prognostic unfavorable (2.72e-4)" "unprognostic (2.98e-2)" "unprognostic (1.77e-2)" "unprognostic (2.58e-2)" "unprognostic (1.36e-2)" "unprognostic (1.94e-1)" "unprognostic (1.40e-1)" "unprognostic (5.08e-2)" "potential prognostic unfavorable (6.73e-4)" "unprognostic (8.81e-2)" "unprognostic (1.55e-1)" "unprognostic (9.54e-3)" "unprognostic (1.04e-1)" FBLL1 LOC345630 ENSG00000188573 "Fibrillarin like 1" A6NHQ2 5 168529305-168530634 "Predicted intracellular proteins" "rRNA processing" "Methyltransferase, Ribonucleoprotein, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 41.4;pituitary gland: 17.2" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 31.9;Brain excitatory neurons: 7.8;Brain inhibitory neurons: 8.9;Corticotrophs: 6.3;Late primary spermatocytes: 6.7;Other brain neurons: 13.7;Pancreatic islet cells: 15.3;Retinal amacrine cells: 5.2;Thyrotrophs: 7.3" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 9.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 7 "Neuroblastoma: 23.6" "Colon - Colon enteroendocrine cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049546, HPA077724" Uncertain Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" "Nucleoli fibrillar center" Nucleoplasm "HPA049546: , HPA077724: " "unprognostic (3.02e-2)" "unprognostic (9.16e-3)" "unprognostic (1.39e-3)" "unprognostic (1.58e-1)" "unprognostic (1.21e-2)" "unprognostic (1.08e-1)" "unprognostic (1.55e-2)" "unprognostic (3.13e-2)" "unprognostic (1.61e-3)" "unprognostic (3.78e-2)" "unprognostic (1.89e-1)" "unprognostic (1.41e-1)" "unprognostic (7.07e-2)" "unprognostic (1.61e-1)" FBLN1 FBLN ENSG00000077942 "Fibulin 1" P23142 22 45502238-45601135 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 1775.4" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 687.6;Cytotrophoblasts: 845.8;Decidual stromal cells: 1116.5;Endometrial glandular cells: 398.2;Endometrial stromal cells: 689.3;Extravillous trophoblasts: 993.6;Fibro-adipogenic progenitors: 374.6;Fibroblasts: 1820.2;Hepatic stellate cells: 400.2;Migrating cytotrophoblasts: 731.1;Syncytiotrophoblasts: 1557.0" "Group enriched" "Detected in many" 4 "choroid plexus epithelial cell: 514.9;fibroblast: 764.6" "Cancer enhanced" "Detected in all" "Uterine Corpus Endometrial Carcinoma (TCGA): 641.7" "Region enriched" "Detected in all" 13 "choroid plexus: 1731.1" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Adrenal gland - Fibroblasts, Breast - Fibroblasts, Colon - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblasts_2, Pancreas - Fibroblasts, Pituitary gland - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblasts_2, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001612, HPA001613, CAB004393, CAB068187" Enhanced Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" Other NA NA 5600000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 8 "Endoplasmic reticulum" "CAB004393: , CAB068187: , HPA001612: , HPA001613: " "potential prognostic favorable (2.24e-4)" "unprognostic (1.84e-1)" "unprognostic (1.64e-2)" "unprognostic (2.56e-1)" "unprognostic (1.77e-1)" "unprognostic (3.62e-1)" "potential prognostic unfavorable (7.09e-4)" "unprognostic (6.87e-2)" "unprognostic (6.92e-2)" "unprognostic (8.56e-3)" "potential prognostic unfavorable (6.46e-4)" "unprognostic (3.20e-2)" "potential prognostic unfavorable (5.88e-5)" "unprognostic (6.51e-3)" "unprognostic (1.17e-1)" "unprognostic (8.59e-2)" "unprognostic (5.73e-2)" "unprognostic (1.03e-1)" "unprognostic (4.11e-1)" "unprognostic (7.32e-3)" "unprognostic (5.96e-3)" "unprognostic (1.53e-1)" "unprognostic (1.33e-2)" "unprognostic (1.93e-2)" "unprognostic (3.89e-2)" "unprognostic (7.92e-3)" "unprognostic (8.48e-2)" "unprognostic (2.41e-3)" "unprognostic (1.88e-1)" "unprognostic (2.11e-2)" "unprognostic (3.31e-2)" FBLN2 ENSG00000163520 "Fibulin 2" P98095 3 13549125-13638422 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 287.6" "Cell type enhanced" "Detected in many" "Adipocytes: 85.7;Decidual stromal cells: 262.3;Endometrial stromal cells: 91.9;Fibro-adipogenic progenitors: 228.7;Fibroblasts: 430.8;Hepatic stellate cells: 71.0;Leydig cells: 193.7;Peritubular myoid cells: 263.7;Salivary duct cells: 97.0;Schwann cells: 86.1;Sertoli cells: 73.7" "Cell type enriched" "Detected in many" 8 "fibroblast: 337.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 6.7;naive CD8 T-cell: 3.7" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 92.6" "Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblasts_2, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblasts_2, Spleen - B-cells (Spleen), Stomach - Fibroblasts" "Group enriched" "Detected in many" 4 "olfactory bulb: 12.4;white matter: 3.1" "Low region specificity" "Detected in all" "HPA001934, CAB018622" Enhanced Uncertain "Plasma membrane" "Secreted to extracellular matrix" "No annotated function" NA NA 11000000 "Cluster 18: Non-specific - Translation" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 51: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 12 "Plasma membrane" "CAB018622: , HPA001934: " "unprognostic (5.76e-2)" "unprognostic (1.16e-1)" "unprognostic (3.06e-1)" "unprognostic (4.69e-2)" "unprognostic (1.24e-1)" "unprognostic (1.14e-1)" "unprognostic (4.67e-3)" "unprognostic (3.53e-3)" "unprognostic (6.80e-2)" "unprognostic (6.09e-2)" "validated prognostic favorable (3.18e-4)" "validated prognostic favorable (9.74e-6)" "unprognostic (1.54e-3)" "potential prognostic favorable (3.34e-4)" "unprognostic (7.68e-3)" "unprognostic (2.96e-1)" "unprognostic (2.93e-1)" "unprognostic (1.02e-2)" "unprognostic (3.70e-1)" "unprognostic (2.22e-2)" "potential prognostic unfavorable (9.28e-6)" "unprognostic (3.51e-1)" "unprognostic (5.18e-2)" "unprognostic (1.67e-2)" "unprognostic (1.12e-1)" "potential prognostic favorable (1.55e-4)" "unprognostic (1.26e-1)" "unprognostic (2.68e-2)" "unprognostic (9.63e-2)" "unprognostic (6.57e-2)" "unprognostic (1.71e-2)" FBLN5 "ARMD3, DANCE, EVEC, UP50" ENSG00000140092 "Fibulin 5" Q9UBX5 14 91869411-91947987 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Age-related macular degeneration, Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 668.4" "Group enriched" "Detected in many" 7 "Decidual stromal cells: 253.5;Fibro-adipogenic progenitors: 270.3;Fibroblasts: 322.1;Hepatic stellate cells: 464.7;Leydig cells: 705.7;Peritubular myoid cells: 856.1" "Cell type enhanced" "Detected in many" "endothelial cell: 83.2;fibroblast: 161.6" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 106.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 6.7" "Lineage enriched" "Detected in many" 4 "granulocytes: 6.7" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Minor Salivary Gland - Macrophages, Prostate - Fibroblasts, Spleen - Fibroblasts_1, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000848, HPA000868, CAB025843" Supported Uncertain "Plasma membrane" "Secreted to extracellular matrix" "Cell adhesion" NA NA 10000000 "Cluster 41: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 16 "Plasma membrane" "CAB025843: , HPA000848: , HPA000868: " "unprognostic (1.27e-2)" "unprognostic (8.52e-3)" "unprognostic (2.98e-2)" "unprognostic (6.88e-3)" "unprognostic (6.42e-2)" "unprognostic (3.38e-1)" "unprognostic (4.40e-3)" "unprognostic (1.37e-2)" "unprognostic (1.01e-1)" "unprognostic (3.80e-3)" "unprognostic (3.85e-2)" "unprognostic (1.78e-3)" "unprognostic (1.50e-1)" "validated prognostic favorable (8.72e-4)" "validated prognostic favorable (9.07e-5)" "unprognostic (2.69e-3)" "unprognostic (6.11e-3)" "unprognostic (1.60e-1)" "unprognostic (5.08e-1)" "unprognostic (5.75e-3)" "unprognostic (8.12e-3)" "unprognostic (3.78e-2)" "unprognostic (1.96e-1)" "unprognostic (7.78e-2)" "unprognostic (1.28e-2)" "unprognostic (6.63e-2)" "unprognostic (5.10e-2)" "potential prognostic unfavorable (1.47e-4)" "unprognostic (1.66e-1)" "unprognostic (2.34e-2)" "unprognostic (2.22e-1)" FBLN7 "FLJ37440, TM14" ENSG00000144152 "Fibulin 7" Q53RD9 2 112138385-112188218 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" Heparin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ependymal cells: 55.2;Lactotrophs: 39.3;Melanocytes: 28.9;Myosatellite cells: 60.6;Oocytes: 165.8;Rod photoreceptor cells: 36.3;Somatotrophs: 65.7;Thyrotrophs: 80.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 26 "memory CD4 T-cell: 34.5;naive CD4 T-cell: 29.6;T-reg: 36.6" "Lineage enriched" "Detected in many" 35 "T-cells: 36.6" "Cancer enhanced" "Detected in many" "thyroid cancer: 17.4" "Breast - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatocytes, Minor Salivary Gland - Fibroblasts, Pituitary gland - Lactotropes, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA034992 Approved "Plasma membrane,Cell Junctions" "Secreted to extracellular matrix" "Cell adhesion" NA NA 310000 "Cluster 31: T-cells - T-cell receptor" "Cluster 64: Non-specific - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 108: Fibroblasts - ECM organization" "Plasma membrane" "Cell Junctions" "HPA034992: " "unprognostic (1.48e-1)" "unprognostic (3.08e-1)" "unprognostic (3.05e-1)" "unprognostic (1.39e-2)" "unprognostic (2.33e-2)" "unprognostic (8.00e-2)" "unprognostic (1.33e-1)" "potential prognostic unfavorable (9.47e-5)" "unprognostic (6.04e-3)" "unprognostic (9.93e-3)" "unprognostic (2.40e-1)" "unprognostic (5.36e-2)" "potential prognostic favorable (2.30e-5)" "unprognostic (2.35e-1)" "unprognostic (3.65e-3)" "unprognostic (1.42e-1)" "unprognostic (2.72e-1)" "unprognostic (8.69e-2)" "unprognostic (2.88e-1)" "unprognostic (3.38e-1)" "unprognostic (5.78e-2)" "unprognostic (3.90e-2)" "unprognostic (3.54e-2)" "unprognostic (7.44e-2)" "unprognostic (3.41e-1)" "unprognostic (5.11e-2)" "unprognostic (3.47e-2)" "unprognostic (7.65e-2)" "unprognostic (1.97e-1)" "unprognostic (4.74e-3)" "unprognostic (8.33e-2)" FBN1 "FBN, MASS, MFS1, OCTD, SGS, WMS" ENSG00000166147 "Fibrillin 1" P35555 15 48408313-48645721 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Heparin-binding, Hormone" "Aortic aneurysm, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 49.5;placenta: 61.7" "Cell type enhanced" "Detected in many" "Adipocytes: 338.4;Cytotrophoblasts: 303.0;Fibro-adipogenic progenitors: 1451.2;Fibroblasts: 743.1;Hepatic stellate cells: 490.6;Leydig cells: 670.7;Myosatellite cells: 334.9;Oligodendrocytes: 251.2;Peritubular myoid cells: 574.9;Pituicytes/FSCs: 251.4" "Cell type enhanced" "Detected in all" "midbrain-derived inhibitory: 794.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 71.3" "Adipose subcutaneous - Adipose progenitor cells, Colon - Fibroblasts, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblasts_2, Skeletal muscle - Fibroblasts, Skin - Fibroblasts_2, Spleen - Fibroblasts_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002670, HPA017759, HPA021057, CAB058696, CAB068188, CAB080202" Enhanced Approved "Golgi apparatus,Plasma membrane" "Secreted to blood" Hormone NA NA 50600000 110000000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 45: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 8 "Golgi apparatus" "Plasma membrane" "CAB002670: , CAB058696: , CAB068188: , CAB080202: , HPA017759: , HPA021057: " "unprognostic (4.22e-2)" "unprognostic (4.58e-2)" "unprognostic (1.02e-1)" "unprognostic (6.38e-3)" "unprognostic (4.84e-2)" "unprognostic (2.72e-1)" "unprognostic (1.40e-1)" "unprognostic (1.72e-1)" "unprognostic (4.57e-2)" "potential prognostic unfavorable (5.17e-5)" "unprognostic (3.26e-3)" "unprognostic (4.60e-2)" "unprognostic (5.76e-3)" "unprognostic (1.63e-1)" "unprognostic (4.06e-2)" "unprognostic (1.66e-1)" "unprognostic (6.43e-2)" "unprognostic (7.41e-2)" "unprognostic (2.68e-1)" "unprognostic (3.56e-3)" "potential prognostic unfavorable (6.96e-7)" "unprognostic (9.85e-2)" "unprognostic (1.23e-1)" "unprognostic (1.75e-1)" "unprognostic (3.22e-1)" "unprognostic (8.10e-3)" "unprognostic (2.34e-2)" "unprognostic (3.39e-3)" "unprognostic (7.81e-2)" "unprognostic (9.39e-3)" "unprognostic (2.67e-1)" FBN2 "CCA, DA9" ENSG00000138829 "Fibrillin 2" P35556 5 128257909-128659185 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" Hormone "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "placenta: 63.2" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 721.7;Cardiomyocytes: 232.1;Cytotrophoblasts: 1452.5;Migrating cytotrophoblasts: 435.8;Pituitary stem cells: 485.1;Syncytiotrophoblasts: 379.5" "Cell type enhanced" "Detected in many" "LAMP5-LHX6 and Chandelier: 117.3;midbrain-derived inhibitory: 237.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 2.2" "Lineage enriched" "Detected in single" 6 "monocytes: 2.2" "Cancer enhanced" "Detected in many" "Sarcoma: 46.8" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Region enhanced" "Detected in single" "olfactory bulb: 2.0" "Low region specificity" "Detected in many" "HPA012853, CAB026401" Enhanced Approved "Nucleoplasm,Primary cilium,Cytosol" "Secreted to blood" Hormone NA NA 4700000 "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 3: Choroid plexus - Cilium" "Cluster 3: Rhabdoid - Membrane components" "Cluster 63: Cytotrophoblasts - Basic cellular functions" Cytosol "Nucleoplasm, Primary cilium" "CAB026401: , HPA012853: " "unprognostic (1.59e-2)" "unprognostic (1.97e-1)" "unprognostic (1.66e-1)" "unprognostic (3.39e-2)" "unprognostic (6.04e-2)" "unprognostic (1.79e-2)" "potential prognostic favorable (4.70e-4)" "unprognostic (2.72e-1)" "unprognostic (6.24e-3)" "unprognostic (8.11e-3)" "unprognostic (2.49e-2)" "unprognostic (1.61e-1)" "unprognostic (2.61e-1)" "unprognostic (2.44e-1)" "unprognostic (5.10e-2)" "unprognostic (9.78e-2)" "unprognostic (8.50e-2)" "unprognostic (1.21e-1)" FBN3 KIAA1776 ENSG00000142449 "Fibrillin 3" Q75N90 19 8065402-8149592 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 2.3;salivary gland: 4.0" "Cell type enhanced" "Detected in some" "Epididymal clear cells: 47.0;Granulosa cells: 29.2;Lacrimal acinar cells: 11.8;Oligodendrocyte progenitor cells: 28.6;Pituitary stem cells: 21.3;Renal collecting duct intercalated cells: 85.5;Sertoli cells: 17.7" "Group enriched" "Detected in many" 8 "CGE interneuron: 12.9;oligodendrocyte precursor cell: 38.4" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 19.7;Testicular Germ Cell Tumor (TCGA): 16.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 3.9;testis cancer: 4.2" "Breast - Breast glandular cells, Kidney - Intercalated cells" "Low region specificity" "Detected in single" HPA049482 Uncertain "Secreted to extracellular matrix" "No annotated function" NA NA 170000 "Cluster 72: Kidney - Transmembrane transport" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" "HPA049482: " "unprognostic (1.78e-1)" "unprognostic (1.90e-1)" "unprognostic (4.01e-1)" "unprognostic (3.40e-2)" "unprognostic (9.85e-2)" "unprognostic (3.66e-2)" "unprognostic (3.42e-2)" "unprognostic (9.14e-3)" "unprognostic (7.19e-2)" "unprognostic (2.92e-1)" "unprognostic (2.72e-1)" "unprognostic (1.38e-1)" "unprognostic (8.57e-2)" FBP1 FBP ENSG00000165140 "Fructose-bisphosphatase 1" P09467 9 94603133-94640249 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Gluconeogenesis" "Allosteric enzyme, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 289.1;kidney: 275.8;liver: 819.2" "Cell type enhanced" "Detected in many" "Breast lactating cells: 266.9;Enterocytes: 1019.3;Hepatocytes: 665.7;Prostatic club cells: 456.7;Prostatic hillock cells: 169.4;Urothelial cells: 472.4" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 12.4;leukocyte: 9.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 403.7" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "breast cancer: 70.7" "Adipose subcutaneous - Macrophages, Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Breast - Breast glandular cells, Heart muscle - Macrophages, Kidney - Proximal tubular cells, Liver - Hepatocytes, Pituitary gland - Gonadotropes, Skeletal muscle - Macrophages, Skin - Inner root sheath cells, Spleen - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA005857, HPA012513, CAB033869" Enhanced Approved Mitochondria NA NA 18000000 "Cluster 25: Non-specific - Unknown function" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 27: Breast cancer - Unknown function" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 24 Mitochondria "CAB033869: , HPA005857: , HPA012513: " "potential prognostic favorable (8.84e-5)" "unprognostic (1.88e-2)" "unprognostic (4.70e-1)" "unprognostic (7.31e-2)" "unprognostic (2.20e-1)" "unprognostic (1.35e-1)" "unprognostic (3.13e-3)" "unprognostic (1.60e-2)" "unprognostic (1.79e-1)" "unprognostic (1.44e-1)" "validated prognostic favorable (1.81e-7)" "validated prognostic favorable (4.11e-5)" "unprognostic (2.19e-3)" "unprognostic (1.90e-3)" "unprognostic (2.10e-3)" "potential prognostic favorable (3.82e-4)" "unprognostic (3.20e-2)" "unprognostic (4.65e-2)" "unprognostic (4.66e-2)" "unprognostic (2.43e-1)" "unprognostic (6.81e-3)" "unprognostic (6.34e-2)" "potential prognostic favorable (4.91e-4)" "unprognostic (2.61e-1)" "unprognostic (9.24e-2)" "unprognostic (9.40e-3)" "unprognostic (8.05e-2)" "unprognostic (1.83e-1)" "unprognostic (5.68e-2)" "unprognostic (8.60e-2)" "unprognostic (1.34e-1)" FBP2 ENSG00000130957 "Fructose-bisphosphatase 2" O00757 9 94558720-94593824 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Gluconeogenesis" "Allosteric enzyme, Hydrolase" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "choroid plexus: 217.1;skeletal muscle: 706.1;tongue: 359.7" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 192.1;Differentiating spermatogonia: 15.1;Gastric chief cells: 68.8;Mucous neck cells: 37.2;Myonuclei: 87.7;Oocytes: 36.8;Parietal cells: 15.9" "Cell type enriched" "Detected in some" 17 "choroid plexus epithelial cell: 170.6" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in many" 12 "choroid plexus: 155.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Skin - Sebaceous gland cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA012513, HPA077371" Enhanced Approved "Plasma membrane,Cytosol" NA NA 1900000 "Cluster 25: Non-specific - Basic cellular processes" "Cluster 36: Choroid plexus - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 8 "Plasma membrane, Cytosol" "HPA012513: , HPA077371: " "unprognostic (2.92e-1)" "unprognostic (2.03e-1)" "unprognostic (9.47e-2)" "unprognostic (2.51e-1)" "unprognostic (1.39e-2)" "unprognostic (3.21e-2)" "unprognostic (1.04e-2)" "unprognostic (5.31e-2)" "unprognostic (1.99e-2)" "unprognostic (3.64e-2)" FBRS "FBS, FBS1, FLJ11618" ENSG00000156860 Fibrosin Q9HAH7 16 30658431-30670810 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 121.9;Late spermatids: 191.8;Neutrophils: 172.1;Platelets: 140.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044117 Approved Approved Nucleoplasm NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 67: Testis - Mixed function" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 19 Nucleoplasm "HPA044117: " "unprognostic (1.53e-2)" "unprognostic (5.15e-1)" "unprognostic (7.98e-2)" "unprognostic (2.19e-1)" "unprognostic (2.50e-1)" "unprognostic (1.39e-1)" "unprognostic (1.71e-1)" "unprognostic (1.31e-1)" "unprognostic (1.07e-1)" "unprognostic (3.63e-1)" "unprognostic (2.48e-1)" "unprognostic (2.67e-1)" "unprognostic (2.65e-1)" "potential prognostic unfavorable (1.71e-4)" "unprognostic (1.19e-1)" "unprognostic (2.11e-2)" "unprognostic (1.10e-1)" "unprognostic (8.74e-2)" "unprognostic (1.36e-2)" "unprognostic (6.57e-2)" "unprognostic (1.85e-2)" "unprognostic (2.43e-2)" "potential prognostic unfavorable (9.21e-4)" "unprognostic (4.13e-2)" "unprognostic (3.66e-1)" "unprognostic (2.21e-1)" "unprognostic (8.55e-2)" "unprognostic (2.19e-1)" "unprognostic (8.17e-2)" "unprognostic (5.03e-2)" "unprognostic (1.69e-2)" FBRSL1 KIAA1545 ENSG00000112787 "Fibrosin like 1" Q9HCM7 12 132489551-132585188 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Sertoli cells: 106.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Pituitary gland - Corticotropes, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049880 Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 82: Dendritic cells - Antigen presentation" 12 "Nucleoplasm, Cytosol" "Plasma membrane" "HPA049880: " "unprognostic (1.13e-1)" "unprognostic (1.77e-1)" "unprognostic (6.54e-1)" "unprognostic (5.21e-2)" "unprognostic (4.93e-2)" "unprognostic (1.02e-1)" "unprognostic (1.97e-1)" "unprognostic (2.56e-2)" "unprognostic (1.60e-1)" "unprognostic (2.03e-1)" "unprognostic (2.67e-1)" "unprognostic (1.47e-1)" "unprognostic (1.01e-2)" "unprognostic (9.31e-2)" "unprognostic (1.16e-1)" "unprognostic (2.95e-1)" "unprognostic (2.06e-1)" "unprognostic (3.19e-1)" "unprognostic (7.69e-3)" "unprognostic (2.15e-1)" "unprognostic (2.14e-1)" "potential prognostic favorable (4.15e-4)" "unprognostic (4.85e-2)" "potential prognostic unfavorable (1.04e-4)" "unprognostic (2.93e-1)" "potential prognostic favorable (2.55e-4)" "unprognostic (7.65e-2)" "unprognostic (2.39e-1)" "unprognostic (8.14e-2)" "unprognostic (4.39e-3)" "unprognostic (1.38e-1)" FBXL12 "Fbl12, FLJ20188" ENSG00000127452 "F-box and leucine rich repeat protein 12" Q9NXK8 19 9810267-9827816 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 75.0;Syncytiotrophoblasts: 83.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002843 Approved Approved Mitochondria NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 49: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 23: Non-specific - Transcription" "Cluster 108: Fibroblasts - ECM organization" 19 Mitochondria "HPA002843: " "unprognostic (6.88e-2)" "unprognostic (1.56e-1)" "unprognostic (5.57e-2)" "unprognostic (1.73e-1)" "unprognostic (1.16e-1)" "unprognostic (1.17e-1)" "unprognostic (1.05e-1)" "unprognostic (1.77e-1)" "potential prognostic favorable (4.98e-4)" "unprognostic (1.00e-1)" "unprognostic (2.61e-2)" "unprognostic (4.48e-2)" "unprognostic (4.03e-2)" "potential prognostic unfavorable (7.20e-5)" "unprognostic (3.14e-2)" "unprognostic (4.72e-1)" "unprognostic (7.61e-2)" "unprognostic (5.63e-2)" "unprognostic (3.44e-3)" "unprognostic (4.92e-3)" "unprognostic (4.45e-1)" "unprognostic (4.21e-2)" "unprognostic (2.69e-1)" "unprognostic (4.77e-3)" "unprognostic (2.95e-3)" "unprognostic (1.45e-1)" "potential prognostic unfavorable (2.40e-5)" "unprognostic (1.08e-1)" "unprognostic (2.42e-1)" "unprognostic (2.57e-1)" "unprognostic (1.25e-2)" FBXL13 "CFAP169, DRC6, Fbl13, MGC21636" ENSG00000161040 "F-box and leucine rich repeat protein 13" Q8NEE6 7 102811189-103074839 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "stomach 1: 4.8;testis: 3.7" "Cell type enhanced" "Detected in many" "Early spermatids: 267.6;Ependymal cells: 459.4;Epicardial cells: 293.4;Fallopian tube ciliated cells: 328.2;Late spermatids: 747.8;Mucous neck cells: 243.6;Neutrophils: 625.4;Respiratory ciliated cells: 467.8" "Cell type enhanced" "Detected in all" "ependymal cell: 495.4" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 51 "eosinophil: 14.8;neutrophil: 56.7" "Lineage enriched" "Detected in single" 148 "granulocytes: 56.7" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA057232 Uncertain NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 48: Non-specific - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 24: Neutrophils - Innate immunity signal integration" 1 "HPA057232: " "unprognostic (3.99e-1)" "unprognostic (1.36e-1)" "unprognostic (4.42e-2)" "unprognostic (5.35e-2)" "unprognostic (1.01e-1)" "unprognostic (3.95e-2)" "unprognostic (7.45e-3)" "unprognostic (1.83e-1)" FBXL14 "Fbl14, MGC40195" ENSG00000171823 "F-box and leucine rich repeat protein 14" Q8N1E6 12 1565993-1594581 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 93.2;Late spermatids: 129.9;Pancreatic duct cells: 78.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" HPA053889 Approved NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 36: Brain & Liver - Signaling" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 75: Non-specific - Chaperones and protein folding" 16 "HPA053889: " "unprognostic (6.06e-2)" "unprognostic (7.98e-2)" "unprognostic (2.00e-1)" "unprognostic (5.89e-3)" "unprognostic (1.02e-1)" "unprognostic (6.22e-3)" "unprognostic (2.74e-1)" "unprognostic (1.46e-1)" "unprognostic (1.89e-1)" "unprognostic (3.80e-2)" "potential prognostic favorable (3.63e-5)" "unprognostic (2.56e-2)" "unprognostic (8.46e-2)" "unprognostic (1.87e-1)" "unprognostic (1.20e-1)" "unprognostic (1.33e-2)" "unprognostic (1.53e-1)" "unprognostic (6.86e-2)" "unprognostic (5.82e-2)" "unprognostic (7.47e-2)" "unprognostic (2.43e-1)" "unprognostic (1.09e-1)" "unprognostic (3.08e-1)" "unprognostic (1.51e-1)" "unprognostic (1.54e-2)" "unprognostic (1.22e-1)" "unprognostic (8.54e-2)" "unprognostic (2.26e-2)" "unprognostic (2.56e-1)" "unprognostic (1.49e-1)" "unprognostic (1.07e-1)" FBXL15 "Fbl15, FBXO37, MGC11279" ENSG00000107872 "F-box and leucine rich repeat protein 15" Q9H469 10 102419189-102423136 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Enterocytes: 157.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 52: Non-specific - Mitochondria" "Cluster 97: Non-specific - Cellular respiration" 17 "unprognostic (3.59e-3)" "unprognostic (2.86e-1)" "unprognostic (2.69e-2)" "unprognostic (2.23e-1)" "unprognostic (2.98e-2)" "unprognostic (4.78e-2)" "unprognostic (1.25e-1)" "unprognostic (4.01e-3)" "unprognostic (8.12e-2)" "unprognostic (6.06e-3)" "unprognostic (1.37e-1)" "unprognostic (1.56e-1)" "unprognostic (2.83e-2)" "unprognostic (1.03e-2)" "unprognostic (1.19e-1)" "unprognostic (5.12e-2)" "unprognostic (2.55e-1)" "unprognostic (2.27e-2)" "unprognostic (3.24e-1)" "unprognostic (1.43e-1)" "unprognostic (1.24e-2)" "potential prognostic favorable (5.94e-4)" "unprognostic (4.27e-3)" "unprognostic (1.44e-1)" "unprognostic (6.09e-2)" "unprognostic (1.86e-3)" "unprognostic (1.86e-1)" "unprognostic (1.54e-2)" "unprognostic (1.29e-1)" "unprognostic (1.47e-1)" "unprognostic (2.71e-1)" FBXL16 "C16orf22, Fbl16, MGC33974" ENSG00000127585 "F-box and leucine rich repeat protein 16" Q8N461 16 692498-705808 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 17 "brain: 504.7" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 37.8;Brain inhibitory neurons: 46.3;Corticotrophs: 19.0;Esophageal apical cells: 27.8;Lactotrophs: 17.2;Other brain neurons: 24.1;Retinal amacrine cells: 22.4;Retinal bipolar cells: 33.2;Retinal horizontal cells: 24.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 22.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 32.1" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Stomach - Gastric enteroendocrine cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "amygdala: 307.2;basal ganglia: 914.3;cerebral cortex: 485.6;hippocampal formation: 458.5" "HPA039504, HPA056354" Enhanced NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" 12 "HPA039504: , HPA056354: " "unprognostic (6.35e-3)" "unprognostic (1.10e-2)" "unprognostic (4.52e-2)" "unprognostic (1.06e-2)" "unprognostic (1.46e-2)" "unprognostic (6.02e-2)" "unprognostic (2.03e-3)" "unprognostic (1.01e-1)" "potential prognostic favorable (6.17e-4)" "validated prognostic favorable (8.64e-8)" "validated prognostic favorable (6.87e-5)" "unprognostic (1.53e-1)" "unprognostic (3.53e-2)" "unprognostic (2.21e-2)" "unprognostic (8.49e-2)" "unprognostic (8.78e-2)" "unprognostic (2.78e-2)" "unprognostic (1.17e-3)" "potential prognostic unfavorable (6.82e-4)" "unprognostic (1.98e-1)" "unprognostic (4.67e-2)" "unprognostic (1.47e-1)" "unprognostic (1.71e-2)" FBXL17 "DKFZP434C1715, Fbl17, Fbx13, FBXO13" ENSG00000145743 "F-box and leucine rich repeat protein 17" Q9UF56 5 107859035-108382098 "Predicted intracellular proteins, Predicted membrane proteins" "Neurogenesis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Myonuclei: 1151.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "prostate cancer: 31.9" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036410, HPA036411" Uncertain Supported Nucleoplasm NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 60: Prostate cancer - Unknown function" "Cluster 7: Non-specific - Transcription" 38 Nucleoplasm "HPA036410: , HPA036411: " "unprognostic (1.20e-1)" "unprognostic (2.24e-2)" "unprognostic (5.87e-2)" "unprognostic (3.16e-2)" "unprognostic (6.62e-2)" "unprognostic (1.30e-2)" "unprognostic (4.47e-1)" "unprognostic (1.85e-1)" "unprognostic (2.31e-2)" "unprognostic (2.76e-2)" "validated prognostic favorable (1.97e-9)" "validated prognostic favorable (1.14e-4)" "unprognostic (3.39e-3)" "unprognostic (1.04e-1)" "unprognostic (3.27e-1)" "unprognostic (1.36e-1)" "unprognostic (3.05e-2)" "unprognostic (7.95e-2)" "potential prognostic unfavorable (3.27e-4)" "unprognostic (2.93e-2)" "unprognostic (1.66e-3)" "unprognostic (6.36e-2)" "unprognostic (5.62e-2)" "unprognostic (1.26e-1)" "unprognostic (6.87e-2)" "unprognostic (2.53e-2)" "unprognostic (5.27e-2)" "unprognostic (1.33e-1)" "unprognostic (7.90e-2)" "unprognostic (1.11e-2)" "unprognostic (9.66e-2)" FBXL18 "Fbl18, FLJ11467" ENSG00000155034 "F-box and leucine rich repeat protein 18" Q96ME1 7 5431335-5513809 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 7.4" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 89.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036049 Approved Nucleoplasm,Cytosol No No "Cluster 2: Dendritic cells - Unknown function" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 10 Nucleoplasm Cytosol "HPA036049: " "unprognostic (7.59e-2)" "potential prognostic unfavorable (9.93e-4)" "unprognostic (1.86e-1)" "unprognostic (1.48e-3)" "unprognostic (4.18e-2)" "unprognostic (5.70e-1)" "unprognostic (4.47e-2)" "unprognostic (1.13e-1)" "unprognostic (2.26e-1)" "unprognostic (9.97e-3)" "unprognostic (1.59e-1)" "unprognostic (1.23e-1)" "unprognostic (4.45e-2)" "potential prognostic unfavorable (2.69e-6)" "unprognostic (7.42e-2)" "unprognostic (2.12e-3)" "unprognostic (2.41e-1)" "unprognostic (2.04e-1)" "unprognostic (4.30e-2)" "unprognostic (2.79e-2)" "potential prognostic unfavorable (9.39e-5)" "unprognostic (1.71e-3)" "unprognostic (4.99e-3)" "unprognostic (7.29e-2)" "unprognostic (1.45e-1)" "unprognostic (3.26e-1)" "unprognostic (1.26e-1)" "unprognostic (2.75e-1)" "unprognostic (3.58e-2)" "unprognostic (1.00e-3)" "unprognostic (4.75e-2)" FBXL19 "CXXC11, DKFZp434K0410, Fbl19, JHDM1C" ENSG00000099364 "F-box and leucine rich repeat protein 19" Q6PCT2 16 30923055-30948783 "Predicted intracellular proteins" "Ubl conjugation pathway" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Sertoli cells: 34.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Liver - Vascular endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074250 Approved Nucleoplasm NA No "Cluster 2: Dendritic cells - Unknown function" "Cluster 67: Testis - Mixed function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 11 Nucleoplasm "HPA074250: " "unprognostic (1.79e-1)" "unprognostic (2.76e-2)" "unprognostic (2.55e-2)" "potential prognostic unfavorable (1.21e-5)" "unprognostic (6.19e-2)" "unprognostic (1.90e-2)" "unprognostic (3.55e-1)" "unprognostic (2.34e-3)" "unprognostic (3.29e-1)" "unprognostic (2.30e-1)" "unprognostic (3.36e-3)" "unprognostic (1.70e-2)" "unprognostic (2.08e-1)" "potential prognostic unfavorable (1.96e-4)" "unprognostic (1.49e-2)" "unprognostic (9.85e-3)" "unprognostic (3.16e-1)" "unprognostic (3.60e-2)" "unprognostic (2.32e-2)" "unprognostic (8.15e-3)" "unprognostic (2.86e-2)" "unprognostic (1.45e-2)" "unprognostic (1.47e-2)" "unprognostic (2.56e-2)" "unprognostic (2.73e-2)" "unprognostic (1.16e-1)" "unprognostic (2.98e-2)" "unprognostic (1.21e-2)" "unprognostic (4.56e-2)" "unprognostic (1.51e-1)" "unprognostic (4.22e-2)" FBXL2 "FBL2, FBL3" ENSG00000153558 "F-box and leucine rich repeat protein 2" Q9UKC9 3 33277025-33403662 "Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" Calmodulin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 312.3;Endometrial ciliated cells: 347.1;Ependymal cells: 316.1;Epididymal efferent duct ciliated cells: 282.5;Respiratory ciliated cells: 331.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatic stellate cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003240, HPA061783" Approved Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 1: Neurons - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 51: Secretory epithelial cells - Mixed function" 20 "Plasma membrane" "Nucleoplasm, Nucleoli" "HPA003240: , HPA061783: " "unprognostic (1.97e-1)" "unprognostic (1.38e-1)" "unprognostic (1.54e-2)" "unprognostic (1.13e-1)" "unprognostic (1.19e-1)" "unprognostic (1.12e-1)" "unprognostic (8.97e-3)" "potential prognostic unfavorable (3.55e-4)" "unprognostic (5.06e-2)" "unprognostic (1.09e-2)" "unprognostic (8.01e-2)" "unprognostic (5.38e-2)" "unprognostic (1.74e-1)" "unprognostic (1.90e-2)" "unprognostic (5.61e-2)" "unprognostic (3.56e-2)" "unprognostic (1.77e-3)" "potential prognostic unfavorable (2.86e-5)" "unprognostic (3.78e-2)" "unprognostic (1.51e-1)" "unprognostic (1.01e-1)" "unprognostic (7.55e-2)" "unprognostic (9.69e-3)" "unprognostic (6.72e-2)" FBXL20 "Fbl2, Fbl20, MGC15482" ENSG00000108306 "F-box and leucine rich repeat protein 20" Q96IG2 17 39252663-39402523 "Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 518.6;Sertoli cells: 529.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044748, HPA050397" Uncertain Supported Microtubules NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 39: Testis - Nuclear processes" "Cluster 14: Neurons - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 8 Microtubules "HPA044748: , HPA050397: " "unprognostic (8.56e-2)" "unprognostic (1.99e-2)" "unprognostic (1.25e-1)" "unprognostic (7.32e-2)" "unprognostic (1.76e-1)" "unprognostic (4.19e-2)" "unprognostic (1.53e-1)" "unprognostic (1.51e-3)" "unprognostic (6.90e-2)" "unprognostic (6.13e-2)" "unprognostic (3.21e-3)" "unprognostic (6.61e-3)" "unprognostic (2.65e-1)" "unprognostic (8.67e-3)" "unprognostic (9.24e-2)" "unprognostic (1.16e-1)" "unprognostic (2.64e-1)" "unprognostic (2.34e-1)" "unprognostic (1.21e-1)" "potential prognostic unfavorable (1.12e-4)" "unprognostic (2.55e-2)" "unprognostic (2.53e-1)" "unprognostic (8.32e-3)" "unprognostic (2.27e-1)" "potential prognostic favorable (3.60e-4)" "unprognostic (2.85e-2)" "unprognostic (6.00e-2)" "unprognostic (6.18e-2)" "unprognostic (2.27e-1)" "unprognostic (1.25e-1)" "unprognostic (2.93e-1)" FBXL22 "Fbl22, FLJ39626" ENSG00000197361 "F-box and leucine rich repeat protein 22" Q6P050 15 63597353-63602428 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 49.5;intestine: 55.6" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 21.5;Cardiomyocytes: 29.6;Epididymal principal cells: 37.7;Oocytes: 18.4;Smooth muscle cells: 85.7;Vascular smooth muscle cells: 19.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Breast - Breast myoepithelial cells, Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Skin - Smooth muscle cells, Stomach - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA047624, HPA054627" Uncertain Uncertain Cytosol NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 15: Non-specific - Transcription" "Cluster 60: Prostate cancer - Unknown function" "Cluster 62: Smooth muscle cells - Muscle contraction" 9 Cytosol "HPA047624: , HPA054627: " "potential prognostic favorable (5.61e-4)" "unprognostic (1.23e-1)" "unprognostic (4.98e-2)" "unprognostic (1.70e-1)" "unprognostic (1.30e-3)" "unprognostic (9.71e-2)" "unprognostic (1.30e-1)" "unprognostic (1.31e-2)" "unprognostic (5.72e-2)" "potential prognostic favorable (5.78e-4)" "unprognostic (2.00e-1)" "unprognostic (1.69e-1)" "unprognostic (3.51e-1)" "unprognostic (1.96e-1)" "unprognostic (3.42e-2)" "unprognostic (1.22e-1)" "unprognostic (2.48e-2)" "unprognostic (5.74e-2)" "unprognostic (3.17e-1)" "unprognostic (8.50e-2)" "unprognostic (2.38e-2)" "unprognostic (7.42e-2)" "unprognostic (1.88e-2)" "unprognostic (1.80e-1)" "unprognostic (8.19e-2)" "unprognostic (5.62e-1)" FBXL3 "FBL3, FBL3A, FBXL3A" ENSG00000005812 "F-box and leucine rich repeat protein 3" Q9UKT7 13 76992598-77027195 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Biological rhythms, Ubl conjugation pathway" "Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053283, HPA065626" Enhanced "Nuclear bodies" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 13 "Nuclear bodies" "HPA053283: , HPA065626: " "unprognostic (9.54e-3)" "unprognostic (3.68e-1)" "unprognostic (1.04e-1)" "unprognostic (4.70e-2)" "unprognostic (1.13e-1)" "unprognostic (2.15e-2)" "unprognostic (4.13e-1)" "unprognostic (1.63e-1)" "unprognostic (1.58e-1)" "unprognostic (2.57e-1)" "validated prognostic favorable (7.00e-11)" "validated prognostic favorable (1.07e-5)" "unprognostic (3.50e-2)" "unprognostic (3.29e-1)" "unprognostic (2.76e-1)" "unprognostic (1.17e-1)" "unprognostic (2.42e-2)" "unprognostic (1.19e-1)" "unprognostic (7.20e-2)" "unprognostic (4.97e-2)" "unprognostic (1.40e-2)" "unprognostic (2.96e-1)" "unprognostic (3.03e-1)" "unprognostic (1.05e-1)" "unprognostic (1.41e-2)" "unprognostic (4.51e-2)" "unprognostic (2.55e-2)" "unprognostic (2.40e-2)" "unprognostic (2.52e-1)" "unprognostic (2.13e-1)" "unprognostic (2.99e-1)" FBXL4 "FBL4, FBL5" ENSG00000112234 "F-box and leucine rich repeat protein 4" Q9UKA2 6 98868535-98948006 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029140, CAB033362" Approved Supported "Nuclear speckles" NA NA "Cluster 32: Basophils - Transcription" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 14 "Nuclear speckles" "CAB033362: , HPA029140: " "unprognostic (1.96e-1)" "unprognostic (2.96e-2)" "unprognostic (5.62e-2)" "unprognostic (7.39e-3)" "unprognostic (2.22e-1)" "unprognostic (3.79e-2)" "unprognostic (1.25e-1)" "unprognostic (1.67e-1)" "unprognostic (3.02e-1)" "potential prognostic unfavorable (9.15e-5)" "validated prognostic favorable (8.40e-7)" "validated prognostic favorable (1.67e-4)" "unprognostic (4.63e-2)" "unprognostic (2.76e-1)" "unprognostic (4.11e-1)" "unprognostic (3.78e-1)" "unprognostic (2.30e-2)" "unprognostic (1.33e-1)" "unprognostic (1.28e-1)" "unprognostic (6.22e-2)" "unprognostic (4.59e-2)" "unprognostic (2.04e-1)" "unprognostic (7.10e-2)" "unprognostic (8.26e-2)" "potential prognostic favorable (5.43e-4)" "unprognostic (9.93e-2)" "unprognostic (3.73e-1)" "unprognostic (1.23e-1)" "unprognostic (1.83e-1)" "unprognostic (1.31e-1)" "unprognostic (2.35e-1)" FBXL5 "FBL4, FBL5, FLR1" ENSG00000118564 "F-box and leucine rich repeat protein 5" Q9UKA1 4 15604381-15681679 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Neutrophil progenitors: 899.0;Neutrophils: 1809.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 409.3" "Group enriched" "Detected in all" 5 "dendritic cells: 108.3;granulocytes: 409.3;monocytes: 225.9" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Spleen - Neutrophils_2, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002484 Approved NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 72: Kidney - Transmembrane transport" "Cluster 55: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 21 "HPA002484: " "unprognostic (2.84e-3)" "unprognostic (2.71e-2)" "unprognostic (1.49e-1)" "unprognostic (2.45e-1)" "potential prognostic favorable (2.22e-4)" "unprognostic (3.34e-3)" "unprognostic (1.32e-1)" "unprognostic (2.30e-2)" "unprognostic (1.91e-1)" "unprognostic (2.05e-2)" "validated prognostic favorable (3.68e-9)" "validated prognostic favorable (1.96e-4)" "potential prognostic favorable (9.06e-9)" "unprognostic (5.35e-2)" "unprognostic (1.15e-2)" "unprognostic (2.40e-1)" "unprognostic (2.94e-1)" "unprognostic (1.20e-1)" "unprognostic (1.74e-1)" "unprognostic (7.84e-2)" "unprognostic (9.33e-2)" "unprognostic (9.00e-2)" "unprognostic (1.90e-1)" "unprognostic (2.84e-1)" "unprognostic (3.20e-1)" "unprognostic (2.64e-1)" "unprognostic (3.88e-2)" "unprognostic (1.75e-3)" "unprognostic (2.85e-2)" "unprognostic (6.98e-3)" "unprognostic (7.06e-2)" FBXL6 FBL6 ENSG00000182325 "F-box and leucine rich repeat protein 6" Q8N531 8 144355431-144359376 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast lactating cells: 22.3;Enterocytes: 30.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.6" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008867 Approved Nucleoplasm,Vesicles Yes No "Cluster 29: Non-specific - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 12: Non-specific - Vasculature" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 104: Brain endothelial cells - Blood brain barrier" 49 Nucleoplasm Vesicles "HPA008867: " "unprognostic (2.04e-2)" "unprognostic (3.37e-3)" "unprognostic (1.34e-1)" "unprognostic (3.08e-1)" "unprognostic (3.55e-2)" "unprognostic (2.15e-1)" "unprognostic (2.98e-1)" "potential prognostic favorable (4.26e-4)" "unprognostic (5.92e-3)" "unprognostic (4.59e-1)" "unprognostic (2.32e-3)" "unprognostic (5.09e-3)" "unprognostic (7.19e-2)" "unprognostic (1.29e-1)" "unprognostic (6.26e-2)" "unprognostic (7.90e-2)" "unprognostic (5.81e-2)" "unprognostic (8.00e-2)" "unprognostic (2.85e-2)" "unprognostic (1.33e-2)" "unprognostic (1.85e-3)" "potential prognostic unfavorable (9.40e-4)" "unprognostic (1.95e-2)" "unprognostic (3.82e-2)" "unprognostic (2.68e-2)" "unprognostic (8.39e-2)" "unprognostic (1.12e-3)" "unprognostic (1.01e-1)" "unprognostic (9.01e-2)" "unprognostic (7.39e-2)" "unprognostic (9.31e-2)" FBXL7 "FBL6, FBL7, KIAA0840" ENSG00000183580 "F-box and leucine rich repeat protein 7" Q9UJT9 5 15500180-15939795 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 1878.8;Astrocytes: 1436.9;Choroid plexus epithelial cells: 1467.9;Fibro-adipogenic progenitors: 1682.0;Leydig cells: 980.3;Lymphatic endothelial cells: 933.3;Oligodendrocytes: 952.4;Pituicytes/FSCs: 1530.9;Podocytes: 947.2;Retinal horizontal cells: 1718.9" "Cell type enhanced" "Detected in all" "astrocyte: 1466.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Liver - Vascular endothelial cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA055464 Uncertain NA NA "Cluster 75: Ovary - Mixed function" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 103: Non-specific - Basic cellular processes" 6 "HPA055464: " "unprognostic (2.42e-2)" "unprognostic (2.06e-1)" "unprognostic (9.18e-2)" "unprognostic (1.14e-1)" "unprognostic (1.03e-2)" "unprognostic (1.96e-1)" "unprognostic (1.93e-1)" "unprognostic (8.62e-3)" "unprognostic (5.99e-2)" "unprognostic (5.02e-2)" "unprognostic (4.37e-3)" "unprognostic (1.18e-2)" "unprognostic (2.78e-1)" "potential prognostic unfavorable (1.14e-4)" "unprognostic (1.77e-1)" "unprognostic (1.77e-1)" "unprognostic (1.19e-1)" "unprognostic (6.16e-2)" "unprognostic (2.79e-1)" "unprognostic (1.77e-1)" "unprognostic (2.88e-3)" "unprognostic (2.16e-1)" "unprognostic (3.72e-1)" "unprognostic (2.03e-1)" "unprognostic (2.72e-2)" "unprognostic (5.66e-2)" "unprognostic (8.78e-2)" "unprognostic (2.81e-3)" "unprognostic (1.39e-1)" "potential prognostic unfavorable (8.52e-4)" "unprognostic (1.81e-1)" FBXL8 Fbl8 ENSG00000135722 "F-box and leucine rich repeat protein 8" Q96CD0 16 67159932-67164570 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Tuft cells: 11.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA035587, HPA035588" Uncertain Approved "Golgi apparatus" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 70: Non-specific - Protein processing" "Cluster 6: Non-specific - Immune response" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 65: Non-specific - Cell growth & division" 7 "Golgi apparatus" "HPA035587: , HPA035588: " "unprognostic (5.27e-2)" "unprognostic (3.45e-1)" "unprognostic (6.37e-2)" "unprognostic (6.37e-3)" "unprognostic (3.68e-3)" "unprognostic (1.51e-1)" "unprognostic (2.03e-1)" "unprognostic (1.19e-1)" "unprognostic (1.41e-1)" "unprognostic (9.30e-2)" "unprognostic (7.25e-3)" "unprognostic (2.89e-1)" "unprognostic (3.55e-2)" "unprognostic (1.56e-2)" "unprognostic (6.12e-2)" "unprognostic (1.59e-2)" "unprognostic (2.59e-1)" "unprognostic (7.41e-2)" "unprognostic (1.29e-2)" "unprognostic (6.24e-2)" "unprognostic (1.07e-2)" "unprognostic (7.88e-2)" "unprognostic (4.20e-1)" "unprognostic (1.67e-1)" "unprognostic (7.77e-3)" "unprognostic (4.82e-2)" "unprognostic (1.97e-1)" "unprognostic (2.45e-1)" "unprognostic (1.25e-1)" "unprognostic (1.92e-2)" "unprognostic (1.59e-2)" FBXO10 FBX10 ENSG00000147912 "F-box protein 10" Q9UK96 9 37510892-37576380 "Disease related genes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 27.4" "Cell type enhanced" "Detected in many" "Early spermatids: 36.0;Epididymal principal cells: 9.7;Gonadotrophs: 12.9;Late primary spermatocytes: 9.8;Late spermatids: 42.2;Tuft cells: 11.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory B-cell: 2.1;naive B-cell: 1.3" "Lineage enriched" "Detected in single" 5 "B-cells: 2.1" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002863, HPA072721" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 3 "Nucleoplasm, Cytosol" "HPA002863: , HPA072721: " "unprognostic (1.07e-2)" "unprognostic (4.95e-2)" "unprognostic (1.86e-1)" "unprognostic (1.11e-1)" "unprognostic (1.56e-1)" "unprognostic (1.52e-2)" "unprognostic (2.18e-1)" "unprognostic (2.66e-3)" "unprognostic (5.74e-2)" "unprognostic (8.23e-2)" "potential prognostic favorable (4.81e-4)" "unprognostic (8.44e-2)" "unprognostic (2.13e-3)" "potential prognostic unfavorable (1.34e-4)" "unprognostic (1.37e-1)" "unprognostic (2.16e-1)" "unprognostic (1.69e-1)" "unprognostic (3.02e-1)" "unprognostic (1.03e-1)" "unprognostic (3.10e-2)" "unprognostic (3.75e-1)" "unprognostic (3.58e-3)" "unprognostic (8.62e-3)" "unprognostic (2.84e-1)" "unprognostic (2.43e-1)" "unprognostic (7.21e-2)" "unprognostic (3.73e-2)" "unprognostic (9.65e-2)" "unprognostic (8.98e-2)" "unprognostic (1.54e-1)" "unprognostic (2.17e-1)" FBXO11 "FBX11, UBR6" ENSG00000138081 "F-box protein 11" Q86XK2 2 47789316-47906498 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 971.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002690 Supported Nucleoplasm,Nucleoli NA NA "Cluster 32: Basophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 20: Non-specific - Transcription regulation" 23 "Nucleoplasm, Nucleoli" "HPA002690: " "unprognostic (1.92e-1)" "unprognostic (7.19e-2)" "unprognostic (3.47e-1)" "unprognostic (2.07e-2)" "unprognostic (2.07e-1)" "unprognostic (7.87e-3)" "unprognostic (6.51e-2)" "unprognostic (5.97e-3)" "unprognostic (2.14e-1)" "unprognostic (2.13e-2)" "potential prognostic favorable (2.35e-5)" "unprognostic (9.16e-3)" "unprognostic (4.26e-1)" "unprognostic (3.40e-3)" "unprognostic (6.72e-2)" "unprognostic (3.97e-1)" "unprognostic (1.77e-1)" "unprognostic (1.13e-1)" "unprognostic (9.93e-3)" "unprognostic (3.96e-2)" "unprognostic (2.72e-1)" "unprognostic (9.17e-2)" "unprognostic (3.74e-3)" "unprognostic (1.26e-2)" "unprognostic (2.05e-1)" "unprognostic (3.18e-1)" "unprognostic (7.95e-2)" "unprognostic (2.06e-1)" "unprognostic (2.21e-1)" "unprognostic (1.67e-1)" "unprognostic (1.37e-1)" FBXO15 "FBX15, MGC39671" ENSG00000141665 "F-box protein 15" Q8NCQ5 18 74073353-74147843 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 3.8;testis: 7.2" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 59.9;Endometrial ciliated cells: 66.3;Ependymal cells: 233.3;Epididymal efferent duct ciliated cells: 81.8;Fallopian tube ciliated cells: 85.2;Late primary spermatocytes: 71.0;Respiratory ciliated cells: 143.7" "Cell type enriched" "Detected in all" 7 "ependymal cell: 237.3" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 2.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD4 T-cell: 1.6" "Lineage enriched" "Detected in single" 6 "T-cells: 1.6" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Not detected" "Not detected" "Region enriched" "Detected in all" 6 "basal ganglia: 23.3" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 34: Ciliated cells - Cilia assembly & function" 6 "unprognostic (7.36e-2)" "unprognostic (6.97e-2)" "potential prognostic favorable (3.04e-4)" "unprognostic (1.54e-2)" "unprognostic (2.19e-1)" "unprognostic (1.05e-1)" "unprognostic (1.10e-2)" "unprognostic (1.17e-1)" FBXO16 FBX16 ENSG00000214050 "F-box protein 16" Q8IX29 8 28348287-28490278 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 17.3;pituitary gland: 16.7" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 111.8;Corticotrophs: 226.9;Epididymal principal cells: 141.0;Gonadotrophs: 221.7;Lactotrophs: 264.6;Rod photoreceptor cells: 193.7;Somatotrophs: 275.1;Thyrotrophs: 222.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 13 "plasmacytoid DC: 8.8" "Lineage enriched" "Detected in single" 15 "dendritic cells: 8.8" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Prostate - Prostate glandular cells, Skin - Outer root sheath cells, Spleen - Plasma cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058676, HPA076472" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 22: Epididymis - Mixed function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 9 "Nucleoplasm, Vesicles, Plasma membrane, Cytosol" "HPA058676: , HPA076472: " "unprognostic (6.37e-2)" "unprognostic (2.75e-1)" "unprognostic (1.74e-1)" "unprognostic (1.29e-1)" "unprognostic (1.33e-3)" "unprognostic (6.61e-2)" "unprognostic (3.63e-2)" "unprognostic (1.51e-1)" "unprognostic (1.32e-1)" "unprognostic (1.20e-3)" "unprognostic (1.80e-2)" "unprognostic (2.65e-1)" "unprognostic (5.22e-2)" "unprognostic (1.31e-2)" "unprognostic (1.44e-1)" "unprognostic (3.39e-2)" "unprognostic (3.66e-1)" "unprognostic (1.17e-1)" "unprognostic (1.41e-1)" "unprognostic (3.04e-3)" "unprognostic (1.24e-3)" "unprognostic (2.05e-2)" "unprognostic (2.92e-3)" "unprognostic (1.63e-1)" "unprognostic (9.78e-2)" "unprognostic (8.26e-2)" "unprognostic (2.19e-1)" "unprognostic (2.60e-2)" "unprognostic (7.40e-2)" "unprognostic (8.42e-2)" "unprognostic (1.53e-1)" FBXO17 "FBG4, Fbx17, FBXO26, FLJ11798, FLJ25205, MGC9379" ENSG00000269190 "F-box protein 17" Q96EF6 19 38941401-38975742 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 70.5" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 24.1;Brain inhibitory neurons: 21.5;Choroid plexus epithelial cells: 31.6;Distal convoluted tubule cells: 98.3;Loop of henle epithelial cells: 88.7;Podocytes: 80.8;Proximal tubule cells: 113.2;Renal collecting duct intercalated cells: 62.9;Renal collecting duct principal cells: 34.7;Renal connecting tubule cells: 96.3" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 44.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Heart muscle - Fibroblasts, Spleen - Fibroblasts_1, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 15: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 88: Proximal tubular cells - Transmembrane transport" 41 "unprognostic (5.44e-2)" "unprognostic (1.43e-1)" "unprognostic (8.59e-2)" "unprognostic (1.09e-3)" "unprognostic (1.99e-2)" "unprognostic (1.64e-1)" "unprognostic (3.57e-3)" "potential prognostic unfavorable (4.55e-7)" "unprognostic (2.16e-1)" "unprognostic (3.17e-1)" "potential prognostic favorable (8.93e-4)" "unprognostic (4.35e-2)" "unprognostic (2.92e-1)" "unprognostic (1.28e-1)" "unprognostic (8.55e-2)" "potential prognostic unfavorable (1.37e-4)" "unprognostic (1.10e-1)" "unprognostic (6.77e-2)" "unprognostic (4.10e-1)" "unprognostic (5.15e-3)" "unprognostic (3.12e-1)" "unprognostic (6.31e-3)" "unprognostic (2.00e-1)" "unprognostic (8.89e-3)" "unprognostic (1.49e-1)" "unprognostic (4.97e-2)" "unprognostic (6.57e-3)" "potential prognostic unfavorable (7.59e-4)" "unprognostic (2.64e-2)" "unprognostic (1.64e-2)" FBXO2 "Fbg1, Fbs1, FBX2, Nfb42, OCP1" ENSG00000116661 "F-box protein 2" Q9UK22 1 11637018-11655785 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 374.1;pituitary gland: 136.0" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 266.9;Epididymal principal cells: 126.5;Hepatocytes: 112.8;Medullary thymic epithelial cells: 98.4;Pancreatic acinar cells: 226.7;Salivary myoepithelial cells: 123.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "cervical cancer: 82.5" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005472 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 98: Neurons - Neurotransmission & signaling" 171 "Nucleoplasm, Cytosol" "HPA005472: " "unprognostic (2.65e-2)" "unprognostic (5.43e-2)" "unprognostic (4.33e-2)" "unprognostic (1.11e-1)" "unprognostic (2.29e-1)" "potential prognostic favorable (1.06e-5)" "unprognostic (1.43e-1)" "unprognostic (9.00e-2)" "unprognostic (4.80e-2)" "unprognostic (4.18e-1)" "unprognostic (2.38e-2)" "unprognostic (2.79e-2)" "unprognostic (5.23e-3)" "unprognostic (5.44e-2)" "unprognostic (1.08e-2)" "unprognostic (8.33e-2)" "unprognostic (5.26e-2)" "potential prognostic unfavorable (8.82e-4)" "unprognostic (3.85e-2)" "unprognostic (4.10e-1)" "unprognostic (3.97e-2)" "unprognostic (2.03e-2)" "unprognostic (2.25e-2)" "unprognostic (1.51e-2)" "unprognostic (2.72e-1)" "unprognostic (2.29e-2)" "unprognostic (4.93e-3)" "unprognostic (1.05e-1)" "unprognostic (1.40e-1)" "unprognostic (2.93e-2)" "unprognostic (2.97e-2)" FBXO21 "FBX21, KIAA0875" ENSG00000135108 "F-box protein 21" O94952 12 117141991-117190470 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "fallopian tube: 108.4" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 469.8;Fallopian secretory cells: 487.5;Pituicytes/FSCs: 335.1;Podocytes: 494.5;Sertoli cells: 329.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071452 Approved Approved "Primary cilium,Primary cilium tip,Centrosome,Basal body,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 22: Epididymis - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 38: Non-specific - Transcription" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 12 "Centrosome, Cytosol" "Primary cilium, Primary cilium tip, Basal body" "HPA071452: " "unprognostic (2.30e-2)" "unprognostic (1.36e-2)" "unprognostic (8.39e-2)" "unprognostic (1.61e-1)" "unprognostic (1.80e-2)" "unprognostic (1.58e-2)" "unprognostic (1.58e-1)" "potential prognostic favorable (2.09e-4)" "unprognostic (2.44e-1)" "unprognostic (7.90e-2)" "validated prognostic favorable (1.36e-9)" "validated prognostic favorable (6.22e-7)" "unprognostic (1.73e-1)" "unprognostic (3.62e-1)" "unprognostic (1.96e-1)" "unprognostic (3.05e-1)" "unprognostic (1.65e-1)" "unprognostic (1.19e-1)" "potential prognostic favorable (2.81e-4)" "unprognostic (1.26e-1)" "unprognostic (7.66e-2)" "unprognostic (1.62e-1)" "unprognostic (8.31e-3)" "unprognostic (8.46e-2)" "unprognostic (9.26e-2)" "unprognostic (1.02e-2)" "unprognostic (1.07e-1)" "unprognostic (9.83e-2)" "unprognostic (1.95e-1)" "unprognostic (2.74e-1)" "unprognostic (1.99e-1)" FBXO22 "FBX22, FISTC1" ENSG00000167196 "F-box protein 22" Q8NEZ5 15 75903876-75942511 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 198.7;Rod photoreceptor cells: 186.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 47: Testis - Mixed function" "Cluster 25: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 79: Photoreceptor cells - Phototransduction" 24 "unprognostic (2.16e-1)" "unprognostic (7.11e-2)" "unprognostic (2.15e-1)" "unprognostic (2.33e-1)" "unprognostic (1.51e-2)" "unprognostic (3.72e-1)" "unprognostic (2.23e-2)" "unprognostic (2.46e-1)" "unprognostic (1.54e-2)" "unprognostic (7.22e-2)" "potential prognostic favorable (8.31e-7)" "unprognostic (1.92e-2)" "unprognostic (4.58e-2)" "unprognostic (1.86e-2)" "potential prognostic unfavorable (7.23e-4)" "potential prognostic unfavorable (3.90e-5)" "unprognostic (1.63e-2)" "unprognostic (1.17e-1)" "unprognostic (8.59e-2)" "unprognostic (2.30e-2)" "unprognostic (6.54e-2)" "potential prognostic unfavorable (1.06e-4)" "unprognostic (7.54e-3)" "unprognostic (1.01e-1)" "unprognostic (2.78e-2)" "unprognostic (1.37e-1)" "unprognostic (9.44e-2)" "unprognostic (6.91e-2)" "unprognostic (5.34e-2)" "unprognostic (1.08e-1)" "unprognostic (1.51e-1)" FBXO24 FBX24 ENSG00000106336 "F-box protein 24" O75426 7 100583982-100601117 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 53 "testis: 77.1" "Group enriched" "Detected in many" 4 "Early spermatids: 666.5;Late spermatids: 907.1" "Cell type enhanced" "Detected in some" "fibroblast: 8.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Colon - Enteric glia cells, Kidney - Fibroblasts, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA050951 Enhanced NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 25: Non-specific - Transcription" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 4 "HPA050951: " "unprognostic (5.01e-2)" "unprognostic (2.57e-1)" "unprognostic (5.31e-2)" "unprognostic (2.35e-1)" "unprognostic (1.12e-1)" "potential prognostic unfavorable (5.02e-4)" "unprognostic (1.88e-2)" "unprognostic (1.08e-1)" FBXO25 FBX25 ENSG00000147364 "F-box protein 25" Q8TCJ0 8 406428-477967 "Disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 91.6" "Cell type enhanced" "Detected in all" "Early primary spermatocytes: 317.5;Early spermatids: 536.1;Late primary spermatocytes: 1195.1;Late spermatids: 375.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 57: Testis - Spermatogenesis" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 59: Leukemia - T-cell receptor" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 8 "unprognostic (1.22e-1)" "unprognostic (1.61e-2)" "unprognostic (2.24e-2)" "potential prognostic favorable (7.40e-4)" "unprognostic (4.27e-3)" "unprognostic (3.71e-2)" "unprognostic (1.38e-1)" "unprognostic (6.96e-3)" "unprognostic (7.48e-2)" "potential prognostic unfavorable (6.02e-5)" "validated prognostic favorable (2.06e-6)" "validated prognostic favorable (2.73e-4)" "unprognostic (8.97e-2)" "unprognostic (5.78e-2)" "potential prognostic favorable (9.25e-4)" "unprognostic (3.13e-3)" "unprognostic (6.60e-2)" "unprognostic (2.34e-1)" "unprognostic (6.94e-2)" "unprognostic (3.31e-1)" "potential prognostic unfavorable (2.69e-4)" "unprognostic (2.07e-1)" "unprognostic (2.83e-1)" "unprognostic (1.45e-1)" "unprognostic (1.23e-2)" "unprognostic (1.30e-1)" "unprognostic (1.75e-1)" "unprognostic (4.13e-1)" "unprognostic (1.57e-1)" "unprognostic (2.17e-1)" "unprognostic (1.69e-2)" FBXO27 "Fbg5, Fbx27" ENSG00000161243 "F-box protein 27" Q8NI29 19 38990714-39032785 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 35.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 77.2;Ocular epithelial cells: 44.1;Retinal amacrine cells: 46.3;Syncytiotrophoblasts: 44.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA046800, HPA062242" Approved Approved Nucleoplasm NA NA "Cluster 2: Non-specific - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 7 Nucleoplasm "HPA046800: , HPA062242: " "unprognostic (9.17e-2)" "unprognostic (1.92e-2)" "unprognostic (4.48e-1)" "unprognostic (3.05e-1)" "unprognostic (4.75e-2)" "unprognostic (1.29e-1)" "unprognostic (7.40e-3)" "potential prognostic unfavorable (6.39e-5)" "unprognostic (6.54e-3)" "unprognostic (1.58e-1)" "unprognostic (1.35e-2)" "unprognostic (2.18e-2)" "unprognostic (4.62e-3)" "unprognostic (8.41e-2)" "unprognostic (1.10e-1)" "unprognostic (3.36e-2)" "unprognostic (1.14e-2)" "unprognostic (1.02e-1)" "unprognostic (6.15e-2)" "unprognostic (5.75e-3)" "unprognostic (1.85e-1)" "unprognostic (1.33e-2)" "unprognostic (3.96e-3)" "unprognostic (1.22e-1)" "unprognostic (7.57e-3)" "unprognostic (9.38e-2)" "unprognostic (2.54e-1)" "unprognostic (6.32e-2)" "unprognostic (3.72e-2)" "unprognostic (3.85e-2)" "unprognostic (4.82e-2)" FBXO28 "CENP-30, Fbx28, FLJ10766, KIAA0483" ENSG00000143756 "F-box protein 28" Q9NVF7 1 224114111-224162047 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003289 Approved Supported "Nucleoplasm,Focal adhesion sites" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" 65 Nucleoplasm "Focal adhesion sites" "HPA003289: " "unprognostic (9.04e-2)" "unprognostic (3.47e-3)" "unprognostic (3.10e-1)" "unprognostic (2.79e-2)" "unprognostic (7.92e-2)" "unprognostic (1.13e-1)" "unprognostic (2.33e-2)" "unprognostic (4.34e-2)" "unprognostic (1.53e-1)" "potential prognostic unfavorable (9.42e-4)" "potential prognostic favorable (1.02e-5)" "unprognostic (1.12e-2)" "unprognostic (7.63e-2)" "unprognostic (3.19e-1)" "unprognostic (2.80e-1)" "unprognostic (5.23e-3)" "unprognostic (1.05e-2)" "unprognostic (4.76e-2)" "unprognostic (1.50e-1)" "unprognostic (1.53e-2)" "unprognostic (2.84e-3)" "unprognostic (5.87e-3)" "unprognostic (4.84e-3)" "unprognostic (7.33e-2)" "unprognostic (4.27e-3)" "unprognostic (2.60e-2)" "unprognostic (1.20e-1)" "unprognostic (1.45e-1)" "unprognostic (5.69e-2)" "unprognostic (1.89e-2)" "unprognostic (5.62e-2)" FBXO3 "FBA, FBX3" ENSG00000110429 "F-box protein 3" Q9UK99 11 33740939-33774543 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 165.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002467 Approved Nucleoplasm,Cytosol NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 31: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 17 Nucleoplasm Cytosol "HPA002467: " "unprognostic (8.06e-3)" "unprognostic (7.31e-2)" "unprognostic (2.03e-1)" "unprognostic (3.68e-2)" "unprognostic (1.81e-1)" "unprognostic (4.02e-2)" "unprognostic (2.64e-1)" "unprognostic (1.64e-2)" "unprognostic (6.28e-2)" "unprognostic (1.78e-3)" "validated prognostic favorable (3.88e-13)" "validated prognostic favorable (6.30e-4)" "potential prognostic favorable (3.34e-4)" "unprognostic (2.12e-1)" "unprognostic (3.86e-2)" "unprognostic (4.26e-2)" "unprognostic (2.02e-2)" "unprognostic (8.36e-2)" "unprognostic (6.17e-2)" "unprognostic (2.59e-2)" "potential prognostic unfavorable (3.82e-4)" "unprognostic (5.63e-3)" "unprognostic (3.85e-2)" "unprognostic (1.12e-1)" "unprognostic (1.79e-2)" "unprognostic (1.56e-1)" "unprognostic (1.37e-1)" "unprognostic (2.49e-2)" "unprognostic (1.05e-1)" "unprognostic (3.65e-1)" "unprognostic (3.52e-1)" FBXO30 "Fbx30, MGC21674" ENSG00000118496 "F-box protein 30" Q8TB52 6 145793502-145814795 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "basophil: 9.3" "Lineage enriched" "Detected in many" 6 "granulocytes: 9.3" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Smooth muscle cells, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012583 Approved Approved Microtubules NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 62: Smooth muscle cells - Muscle contraction" 23 Microtubules "HPA012583: " "unprognostic (6.94e-2)" "unprognostic (4.50e-3)" "unprognostic (1.71e-1)" "unprognostic (5.86e-3)" "unprognostic (8.81e-2)" "unprognostic (4.51e-2)" "unprognostic (8.28e-3)" "unprognostic (2.06e-1)" "unprognostic (1.87e-1)" "unprognostic (3.17e-1)" "potential prognostic favorable (7.64e-6)" "unprognostic (3.18e-2)" "unprognostic (1.11e-1)" "potential prognostic unfavorable (5.05e-7)" "unprognostic (1.49e-1)" "unprognostic (4.63e-2)" "unprognostic (1.47e-1)" "unprognostic (2.16e-1)" "unprognostic (8.54e-2)" "unprognostic (6.17e-3)" "unprognostic (7.37e-2)" "unprognostic (6.28e-2)" "unprognostic (5.27e-2)" "unprognostic (2.76e-1)" "unprognostic (5.91e-3)" "unprognostic (1.21e-1)" "unprognostic (2.41e-1)" "unprognostic (2.05e-1)" "unprognostic (7.01e-2)" "unprognostic (1.73e-1)" "unprognostic (2.99e-1)" FBXO31 "FBX14, Fbx31, FBXO14, MGC15419" ENSG00000103264 "F-box protein 31" Q5XUX0 16 87326987-87392142 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, DNA damage, Ubl conjugation pathway" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 60.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 178.0;Early primary spermatocytes: 285.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Pituitary gland - Corticotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030150 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 24: Non-specific - Transcription" "Cluster 35: Non-specific - DNA binding" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 3: Early primary spermatocytes - Early meiosis" 15 Nucleoplasm "Golgi apparatus, Cytosol" "HPA030150: " "unprognostic (1.05e-1)" "unprognostic (4.16e-1)" "unprognostic (1.54e-1)" "unprognostic (5.09e-2)" "unprognostic (9.33e-2)" "unprognostic (3.37e-1)" "unprognostic (1.57e-1)" "potential prognostic favorable (5.96e-5)" "unprognostic (1.03e-1)" "unprognostic (4.97e-3)" "potential prognostic favorable (4.26e-6)" "unprognostic (4.56e-3)" "unprognostic (3.93e-3)" "unprognostic (7.94e-3)" "unprognostic (2.60e-1)" "unprognostic (3.42e-3)" "unprognostic (1.64e-1)" "unprognostic (1.54e-3)" "unprognostic (1.15e-1)" "unprognostic (2.91e-2)" "unprognostic (1.32e-1)" "unprognostic (6.38e-3)" "unprognostic (2.76e-1)" "unprognostic (9.90e-2)" "unprognostic (1.72e-2)" "unprognostic (9.09e-3)" "unprognostic (6.08e-2)" "unprognostic (1.73e-1)" "unprognostic (7.49e-2)" "unprognostic (1.47e-2)" "unprognostic (1.93e-1)" FBXO32 "ATROGIN1, Fbx32, MAFbx" ENSG00000156804 "F-box protein 32" Q969P5 8 123497889-123541206 "Disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "skeletal muscle: 604.9" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 947.2;Myonuclei: 1465.6;Myosatellite cells: 462.0;Salivary myoepithelial cells: 611.5;Smooth muscle cells: 473.4;Thymic myoid cells: 1537.7" "Cell type enhanced" "Detected in all" "oligodendrocyte: 255.7;vascular associated smooth muscle cell: 240.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "basophil: 2.9;gdT-cell: 2.6;MAIT T-cell: 2.5;memory CD4 T-cell: 3.6;memory CD8 T-cell: 3.8;naive CD4 T-cell: 4.2;naive CD8 T-cell: 5.4;NK-cell: 3.2;T-reg: 3.8" "Group enriched" "Detected in many" 8 "granulocytes: 2.9;NK-cells: 3.2;T-cells: 5.4" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058955, HPA065209" Enhanced Nucleoplasm,Cytosol NA NA "Cluster 27: T-cells - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 72: Neuronal - Signal transduction" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 15 "Nucleoplasm, Cytosol" "HPA058955: , HPA065209: " "unprognostic (8.78e-3)" "unprognostic (3.32e-1)" "unprognostic (2.56e-1)" "unprognostic (2.31e-1)" "unprognostic (1.85e-1)" "unprognostic (2.24e-2)" "unprognostic (2.44e-1)" "unprognostic (4.14e-1)" "unprognostic (9.22e-2)" "unprognostic (4.42e-2)" "unprognostic (2.47e-1)" "unprognostic (4.05e-3)" "unprognostic (2.34e-2)" "unprognostic (2.43e-1)" "unprognostic (3.63e-2)" "unprognostic (1.40e-2)" "unprognostic (6.86e-3)" "unprognostic (1.74e-1)" "potential prognostic unfavorable (1.20e-4)" "unprognostic (6.29e-2)" "unprognostic (9.89e-3)" "unprognostic (1.66e-2)" "unprognostic (6.82e-2)" "unprognostic (2.24e-1)" "unprognostic (9.24e-3)" "unprognostic (7.13e-2)" "unprognostic (3.04e-1)" "unprognostic (1.28e-2)" "unprognostic (2.27e-1)" "unprognostic (3.50e-1)" "unprognostic (2.32e-1)" FBXO33 Fbx33 ENSG00000165355 "F-box protein 33" Q7Z6M2 14 39397684-39432466 "Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 50.5" "Cell type enhanced" "Detected in many" "Neutrophils: 493.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046657 Approved Approved Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 53: Neurons - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 10 Nucleoplasm "HPA046657: " "unprognostic (1.46e-1)" "unprognostic (5.77e-3)" "unprognostic (3.10e-1)" "unprognostic (1.19e-1)" "unprognostic (1.16e-1)" "unprognostic (1.90e-1)" "unprognostic (9.51e-2)" "unprognostic (4.68e-3)" "unprognostic (1.18e-1)" "unprognostic (2.64e-2)" "validated prognostic favorable (2.72e-6)" "validated prognostic favorable (4.82e-4)" "unprognostic (1.04e-2)" "unprognostic (4.88e-2)" "unprognostic (2.24e-2)" "unprognostic (1.93e-2)" "unprognostic (4.31e-1)" "unprognostic (1.06e-2)" "unprognostic (7.91e-3)" "unprognostic (1.48e-1)" "unprognostic (7.11e-3)" "unprognostic (2.15e-1)" "unprognostic (2.63e-1)" "unprognostic (1.57e-1)" "unprognostic (1.32e-2)" "unprognostic (9.40e-2)" "unprognostic (1.49e-1)" "unprognostic (2.67e-1)" "unprognostic (2.78e-1)" "unprognostic (2.30e-1)" "unprognostic (6.15e-2)" FBXO34 "Fbx34, FLJ20725" ENSG00000178974 "F-box protein 34" Q9NWN3 14 55271344-55370053 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 698.6;Myonuclei: 588.2;Neutrophils: 720.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast myoepithelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052592 Uncertain Approved "Nuclear speckles,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 51: Neurons - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 103: Non-specific - Basic cellular processes" 25 "Nuclear speckles" Cytosol "HPA052592: " "unprognostic (8.52e-3)" "unprognostic (2.47e-1)" "unprognostic (3.80e-2)" "unprognostic (2.30e-1)" "unprognostic (4.83e-2)" "unprognostic (1.60e-2)" "unprognostic (2.57e-1)" "potential prognostic favorable (5.52e-5)" "unprognostic (6.34e-2)" "unprognostic (5.56e-2)" "validated prognostic favorable (1.38e-9)" "validated prognostic favorable (8.69e-6)" "unprognostic (8.96e-3)" "unprognostic (1.68e-2)" "unprognostic (2.11e-1)" "unprognostic (1.62e-1)" "unprognostic (5.71e-3)" "unprognostic (1.10e-1)" "unprognostic (1.26e-1)" "unprognostic (7.67e-2)" "unprognostic (1.80e-1)" "unprognostic (1.83e-2)" "unprognostic (3.36e-1)" "unprognostic (1.07e-1)" "unprognostic (6.19e-3)" "unprognostic (3.23e-2)" "unprognostic (3.12e-1)" "unprognostic (1.86e-2)" "unprognostic (1.84e-1)" "unprognostic (2.68e-1)" "unprognostic (8.94e-2)" FBXO36 "Fbx36, FLJ37592" ENSG00000153832 "F-box protein 36" Q8NEA4 2 229922302-230013119 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 113.9;Endometrial ciliated cells: 101.7;Ependymal cells: 117.5;Fallopian tube ciliated cells: 105.1;Late primary spermatocytes: 176.8;Respiratory ciliated cells: 172.4;Rod photoreceptor cells: 94.9" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 20.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053865 Approved Nucleoplasm,Nucleoli NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" 1 "Nucleoplasm, Nucleoli" "HPA053865: " "unprognostic (2.51e-1)" "unprognostic (1.45e-1)" "unprognostic (9.92e-2)" "unprognostic (4.03e-2)" "unprognostic (1.53e-3)" "unprognostic (1.45e-1)" "unprognostic (1.41e-1)" "potential prognostic unfavorable (2.85e-5)" "unprognostic (9.18e-2)" "unprognostic (3.32e-1)" "potential prognostic favorable (5.83e-6)" "unprognostic (2.29e-1)" "unprognostic (1.80e-1)" "unprognostic (9.76e-3)" "unprognostic (8.28e-2)" "unprognostic (1.55e-1)" "unprognostic (3.74e-1)" "unprognostic (1.48e-2)" "unprognostic (3.24e-1)" "unprognostic (7.66e-2)" "unprognostic (1.22e-1)" "unprognostic (6.50e-2)" "unprognostic (2.17e-1)" "unprognostic (9.62e-2)" "unprognostic (2.11e-1)" "unprognostic (3.30e-2)" "unprognostic (1.43e-1)" "unprognostic (1.76e-1)" "unprognostic (2.69e-1)" "unprognostic (1.51e-3)" "unprognostic (8.68e-2)" FBXO38 "Fbx38, FLJ13962, MOKA, SP329" ENSG00000145868 "F-box protein 38" Q6PIJ6 5 148383935-148442836 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Adaptive immunity, Immunity, Ubl conjugation pathway" "Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 357.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034821 Approved Approved "Nucleoplasm,Plasma membrane,Primary cilium,Basal body" NA No "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 24: Neutrophils - Innate immunity signal integration" 15 "Nucleoplasm, Plasma membrane" "Primary cilium, Basal body" "HPA034821: " "unprognostic (2.16e-3)" "unprognostic (3.69e-2)" "unprognostic (6.78e-3)" "unprognostic (4.10e-3)" "unprognostic (1.07e-1)" "unprognostic (2.19e-1)" "unprognostic (7.86e-2)" "unprognostic (2.58e-2)" "unprognostic (1.97e-1)" "unprognostic (1.15e-1)" "potential prognostic favorable (1.17e-6)" "unprognostic (3.18e-2)" "unprognostic (1.25e-1)" "unprognostic (6.70e-2)" "unprognostic (4.46e-1)" "unprognostic (2.57e-2)" "unprognostic (1.10e-1)" "unprognostic (2.29e-1)" "unprognostic (3.61e-1)" "unprognostic (3.09e-2)" "unprognostic (1.02e-1)" "unprognostic (2.44e-2)" "unprognostic (2.07e-2)" "unprognostic (1.39e-1)" "unprognostic (3.88e-2)" "unprognostic (1.90e-1)" "unprognostic (1.42e-1)" "unprognostic (3.45e-2)" "unprognostic (2.45e-1)" "unprognostic (2.71e-2)" "unprognostic (1.41e-1)" FBXO39 "CT144, Fbx39, MGC35179" ENSG00000177294 "F-box protein 39" Q8N4B4 17 6776215-6797101 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 28 "testis: 28.5" "Group enriched" "Detected in some" 34 "Early spermatids: 541.8;Late spermatids: 726.6" "Cell type enhanced" "Detected in some" "pericyte: 3.1;vascular associated smooth muscle cell: 3.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" "unprognostic (9.36e-2)" "potential prognostic unfavorable (6.53e-4)" FBXO4 FBX4 ENSG00000151876 "F-box protein 4" Q9UKT5 5 41925254-41941743 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003362 Approved Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 55: Non-specific - Transcription" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 67: Plasma cells - Plasma cell differentiation" 21 Nucleoplasm "HPA003362: " "unprognostic (3.32e-2)" "unprognostic (1.30e-1)" "unprognostic (5.75e-2)" "unprognostic (2.17e-1)" "unprognostic (3.85e-1)" "unprognostic (7.89e-2)" "unprognostic (2.76e-1)" "unprognostic (4.03e-3)" "unprognostic (1.13e-1)" "potential prognostic unfavorable (4.75e-4)" "potential prognostic favorable (5.69e-7)" "unprognostic (2.63e-1)" "unprognostic (3.00e-1)" "unprognostic (2.04e-2)" "unprognostic (3.67e-2)" "unprognostic (1.30e-1)" "unprognostic (8.75e-2)" "unprognostic (3.24e-3)" "unprognostic (1.11e-2)" "unprognostic (6.82e-2)" "unprognostic (2.68e-1)" "unprognostic (1.23e-2)" "unprognostic (1.60e-1)" "unprognostic (6.87e-2)" "unprognostic (1.08e-2)" "unprognostic (2.31e-1)" "unprognostic (1.88e-1)" "unprognostic (6.15e-2)" "unprognostic (8.26e-2)" "unprognostic (5.53e-2)" "unprognostic (3.26e-1)" FBXO40 "Fbx40, KIAA1195" ENSG00000163833 "F-box protein 40" Q9UH90 3 121593379-121630295 "Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 96 "heart muscle: 84.7;skeletal muscle: 152.0;tongue: 93.8" "Group enriched" "Detected in some" 30 "Cardiomyocytes: 428.3;Myonuclei: 492.0" "Cell type enhanced" "Detected in many" "mammillary body: 8.1;MGE interneuron: 8.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes" "Region enhanced" "Detected in some" "pons and medulla: 1.7" "Low region specificity" "Detected in many" NA NA "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 53: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 55: Myocytes - Oxidative muscle function" 9 FBXO41 "Fbx41, KIAA1940" ENSG00000163013 "F-box protein 41" Q8TF61 2 73254682-73284478 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 53.8" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 36.0;Brain inhibitory neurons: 32.9;Gonadotrophs: 44.9;Lactotrophs: 20.6;Other brain neurons: 26.8;Retinal amacrine cells: 30.3;Thyrotrophs: 19.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Breast - Breast glandular cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055246, HPA058386" Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 2: Cerebellar granular cells - Neuronal signaling" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA055246: , HPA058386: " "unprognostic (7.14e-2)" "potential prognostic unfavorable (6.68e-4)" "potential prognostic favorable (9.84e-4)" "unprognostic (9.56e-2)" "unprognostic (8.64e-2)" "unprognostic (1.28e-1)" "unprognostic (5.21e-2)" "unprognostic (1.77e-1)" "unprognostic (6.00e-2)" "potential prognostic unfavorable (3.06e-4)" "unprognostic (3.07e-2)" "unprognostic (1.51e-1)" "unprognostic (3.87e-2)" "unprognostic (8.13e-2)" "unprognostic (1.03e-2)" "unprognostic (1.65e-1)" "unprognostic (1.21e-3)" "unprognostic (1.45e-2)" "unprognostic (4.89e-2)" "unprognostic (1.39e-2)" "unprognostic (3.27e-2)" "unprognostic (7.06e-2)" "unprognostic (4.79e-2)" "unprognostic (3.23e-2)" "unprognostic (4.41e-2)" "unprognostic (4.91e-2)" "unprognostic (2.20e-1)" "unprognostic (1.79e-1)" "unprognostic (7.00e-2)" FBXO42 "Fbx42, KIAA1332" ENSG00000037637 "F-box protein 42" Q6P3S6 1 16246840-16352480 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pancreas - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025071 Approved Approved Nucleoplasm NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 24: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 37: Non-specific - mRNA processing" "Cluster 7: Non-specific - Transcription" 29 Nucleoplasm "HPA025071: " "unprognostic (9.42e-2)" "unprognostic (4.23e-2)" "unprognostic (7.24e-2)" "unprognostic (9.76e-2)" "unprognostic (1.41e-1)" "unprognostic (1.33e-2)" "unprognostic (1.89e-1)" "unprognostic (4.48e-3)" "unprognostic (1.60e-1)" "unprognostic (4.03e-2)" "unprognostic (4.47e-3)" "unprognostic (1.53e-2)" "unprognostic (1.46e-1)" "potential prognostic unfavorable (6.98e-5)" "unprognostic (8.35e-2)" "unprognostic (1.13e-1)" "unprognostic (2.95e-2)" "unprognostic (2.28e-1)" "unprognostic (1.31e-1)" "unprognostic (2.20e-2)" "unprognostic (3.12e-1)" "unprognostic (1.35e-1)" "unprognostic (1.44e-1)" "unprognostic (6.19e-2)" "unprognostic (9.24e-2)" "potential prognostic favorable (8.76e-4)" "unprognostic (8.31e-2)" "unprognostic (8.18e-2)" "unprognostic (5.38e-1)" "unprognostic (6.87e-2)" "unprognostic (1.40e-1)" FBXO43 Fbx43 ENSG00000156509 "F-box protein 43" Q4G163 8 100133351-100145817 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Meiosis, Ubl conjugation pathway" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 10 "testis: 3.0" "Cell type enhanced" "Detected in some" "Early primary spermatocytes: 38.8;Early spermatids: 9.7;Late primary spermatocytes: 41.1;Late spermatids: 10.8;Megakaryocyte progenitors: 12.4;Monocyte progenitors: 12.2;Neutrophil progenitors: 10.8" "Cell type enhanced" "Detected in some" "ependymal cell: 5.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adrenal gland - Mitotic cells (Adrenal gland), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Spleen - Mitotic cells (Spleen), Testis - Early spermatids" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.3" "HPA024292, HPA024295, HPA024824" Uncertain Approved Cytosol NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 40: Non-specific - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 7 Cytosol "HPA024292: , HPA024295: , HPA024824: " "unprognostic (4.19e-3)" "unprognostic (2.86e-1)" "potential prognostic unfavorable (7.87e-4)" "unprognostic (1.35e-3)" FBXO44 "FBG3, FBX30, Fbx44, Fbxo6a, MGC14140" ENSG00000132879 "F-box protein 44" Q9H4M3 1 11654375-11663327 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 260.4" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 62.6;Brain inhibitory neurons: 63.7;Other brain neurons: 50.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003363 Approved Approved Nucleoplasm NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 27: Cerebellum - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 109: Neurons - Neuronal signaling" 12 Nucleoplasm "HPA003363: " "unprognostic (8.00e-2)" "unprognostic (4.64e-1)" "unprognostic (1.71e-1)" "unprognostic (3.60e-2)" "unprognostic (8.83e-2)" "potential prognostic favorable (9.71e-5)" "unprognostic (1.37e-1)" "unprognostic (2.02e-1)" "unprognostic (3.57e-2)" "unprognostic (7.85e-3)" "unprognostic (2.98e-3)" "unprognostic (7.21e-2)" "potential prognostic favorable (9.35e-7)" "unprognostic (1.99e-1)" "unprognostic (3.96e-2)" "unprognostic (9.41e-3)" "unprognostic (1.20e-1)" "unprognostic (5.36e-2)" "unprognostic (3.44e-1)" "unprognostic (1.77e-1)" "unprognostic (3.97e-1)" "potential prognostic favorable (4.94e-4)" "unprognostic (2.60e-3)" "unprognostic (3.38e-1)" "unprognostic (3.67e-2)" "unprognostic (2.84e-3)" "unprognostic (1.13e-1)" "unprognostic (5.95e-2)" "unprognostic (1.78e-1)" "unprognostic (1.41e-1)" "unprognostic (3.87e-1)" FBXO45 Fbx45 ENSG00000174013 "F-box protein 45" P0C2W1 3 196568611-196589059 "Predicted intracellular proteins, Predicted secreted proteins" "Neurogenesis, Ubl conjugation pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040730, HPA075467" Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" "Secreted in other tissues" "Developmental protein" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 34: Non-specific - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 17: Non-specific - RNA processing" 37 "Nucleoplasm, Plasma membrane, Cytosol" Vesicles "HPA040730: , HPA075467: " "unprognostic (1.11e-1)" "unprognostic (1.73e-2)" "unprognostic (1.02e-1)" "unprognostic (6.75e-2)" "unprognostic (1.64e-1)" "unprognostic (3.26e-1)" "unprognostic (1.13e-1)" "unprognostic (3.35e-2)" "unprognostic (1.23e-1)" "potential prognostic unfavorable (3.24e-4)" "unprognostic (2.07e-3)" "unprognostic (1.66e-1)" "unprognostic (2.67e-2)" "validated prognostic unfavorable (4.87e-4)" "validated prognostic unfavorable (4.25e-5)" "validated prognostic unfavorable (1.61e-5)" "validated prognostic unfavorable (4.27e-4)" "unprognostic (3.53e-2)" "unprognostic (1.56e-1)" "unprognostic (1.42e-2)" "unprognostic (4.14e-2)" "unprognostic (1.75e-3)" "potential prognostic unfavorable (8.16e-4)" "potential prognostic unfavorable (3.73e-4)" "unprognostic (5.82e-2)" "unprognostic (5.47e-2)" "unprognostic (9.46e-2)" "unprognostic (6.40e-2)" "unprognostic (8.14e-2)" "unprognostic (1.77e-1)" "unprognostic (3.42e-2)" FBXO46 "20D7-FC4, Fbx46, FBXO34L" ENSG00000177051 "F-box protein 46" Q6PJ61 19 45710629-45730896 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Foveolar cells: 63.1;Suprabasal keratinocytes: 53.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049390 Uncertain Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 49: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 26: Keratinocytes - Keratinization" 5 "Nucleoplasm, Vesicles" Cytosol "HPA049390: " "unprognostic (2.08e-2)" "unprognostic (3.24e-1)" "unprognostic (1.71e-1)" "unprognostic (1.69e-1)" "unprognostic (5.29e-2)" "unprognostic (5.30e-2)" "unprognostic (1.19e-1)" "unprognostic (4.11e-2)" "unprognostic (1.51e-3)" "unprognostic (3.87e-2)" "unprognostic (7.73e-2)" "unprognostic (2.19e-1)" "unprognostic (4.62e-2)" "potential prognostic unfavorable (2.59e-6)" "unprognostic (1.67e-2)" "unprognostic (5.85e-2)" "unprognostic (2.12e-1)" "unprognostic (8.85e-3)" "potential prognostic favorable (8.41e-4)" "unprognostic (5.90e-2)" "unprognostic (2.38e-1)" "unprognostic (1.07e-3)" "unprognostic (8.69e-2)" "unprognostic (3.63e-2)" "unprognostic (1.39e-2)" "unprognostic (4.33e-3)" "unprognostic (1.66e-2)" "unprognostic (2.45e-1)" "unprognostic (1.85e-1)" "unprognostic (1.42e-1)" "unprognostic (1.69e-1)" FBXO47 ENSG00000204952 "F-box protein 47" Q5MNV8 17 38936432-38967403 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 37 "testis: 3.6" "Cell type enriched" "Detected in some" 10 "Early primary spermatocytes: 131.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Spermatocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA057438 Uncertain NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 3: Early primary spermatocytes - Early meiosis" "HPA057438: " FBXO48 ENSG00000204923 "F-box protein 48" Q5FWF7 2 68459422-68467294 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 23.3;Platelets: 21.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA049775, HPA054782" Uncertain Approved "Nuclear bodies" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 20: Non-specific - Transcription regulation" 3 "Nuclear bodies" "HPA049775: , HPA054782: " "unprognostic (1.12e-1)" "unprognostic (6.32e-2)" "unprognostic (5.00e-3)" "unprognostic (7.44e-2)" "unprognostic (1.09e-1)" "unprognostic (9.77e-2)" "unprognostic (6.53e-2)" "potential prognostic favorable (3.27e-4)" "potential prognostic favorable (2.64e-4)" "unprognostic (8.78e-3)" "unprognostic (1.44e-1)" "unprognostic (3.85e-1)" "unprognostic (2.77e-2)" "unprognostic (8.73e-3)" "unprognostic (2.21e-1)" "unprognostic (3.70e-1)" "unprognostic (2.93e-1)" "unprognostic (3.27e-2)" "unprognostic (9.85e-2)" "unprognostic (1.24e-2)" "potential prognostic favorable (6.22e-5)" "unprognostic (4.27e-2)" "unprognostic (1.39e-2)" "unprognostic (1.57e-1)" "unprognostic (1.86e-1)" "unprognostic (2.74e-3)" FBXO5 "EMI1, FBX5, Fbxo31" ENSG00000112029 "F-box protein 5" Q9UKT4 6 152970519-152983579 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 41.6;lymphoid tissue: 25.4" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 46.8;Erythrocyte progenitors: 94.4;Extravillous trophoblasts: 35.4;Megakaryocyte progenitors: 47.6;Monocyte progenitors: 90.0;Neutrophil progenitors: 51.8;Oocytes: 46.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB008106, HPA029048" Approved Supported Nucleoplasm NA Yes "Cluster 24: Non-specific - Transcription" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 25: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 27: Non-specific - Cell proliferation" 38 Nucleoplasm "CAB008106: , HPA029048: " "unprognostic (5.05e-3)" "unprognostic (1.50e-2)" "unprognostic (2.77e-2)" "unprognostic (8.81e-2)" "unprognostic (5.69e-2)" "unprognostic (2.58e-1)" "unprognostic (1.47e-1)" "unprognostic (2.49e-2)" "unprognostic (2.36e-2)" "potential prognostic unfavorable (6.60e-4)" "unprognostic (4.99e-3)" "unprognostic (5.90e-2)" "unprognostic (3.24e-2)" "validated prognostic unfavorable (8.79e-9)" "validated prognostic unfavorable (2.17e-6)" "potential prognostic unfavorable (2.12e-4)" "unprognostic (1.19e-2)" "unprognostic (9.68e-2)" "unprognostic (1.06e-1)" "unprognostic (3.47e-2)" "unprognostic (1.08e-1)" "unprognostic (1.68e-1)" "potential prognostic unfavorable (2.63e-4)" "unprognostic (1.19e-2)" "unprognostic (1.78e-2)" "unprognostic (1.22e-1)" "unprognostic (5.09e-2)" "unprognostic (2.48e-2)" "unprognostic (1.23e-1)" "unprognostic (4.48e-1)" "unprognostic (1.04e-1)" FBXO6 "FBG2, FBS2, FBX6, Fbx6b" ENSG00000116663 "F-box protein 6" Q9NRD1 1 11664200-11674354 "Cancer-related genes, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway, Unfolded protein response" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 77.1;Late spermatids: 189.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051175 Approved NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 18: Liver cancer - Metabolism" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 181 "HPA051175: " "unprognostic (3.75e-2)" "unprognostic (1.79e-2)" "unprognostic (2.18e-1)" "unprognostic (2.24e-1)" "unprognostic (1.57e-2)" "unprognostic (3.02e-3)" "unprognostic (3.63e-2)" "unprognostic (1.55e-2)" "unprognostic (3.86e-2)" "unprognostic (1.28e-2)" "unprognostic (1.29e-3)" "unprognostic (3.61e-1)" "unprognostic (2.00e-1)" "unprognostic (4.97e-3)" "unprognostic (5.27e-2)" "unprognostic (6.99e-2)" "unprognostic (7.70e-2)" "unprognostic (2.23e-1)" "unprognostic (5.07e-1)" "unprognostic (1.21e-3)" "unprognostic (2.61e-1)" "unprognostic (4.72e-3)" "unprognostic (3.48e-1)" "unprognostic (6.02e-2)" "unprognostic (1.39e-1)" "unprognostic (9.19e-3)" "unprognostic (2.76e-1)" "unprognostic (1.86e-2)" "unprognostic (2.50e-1)" "unprognostic (1.29e-1)" "unprognostic (2.21e-2)" FBXO7 "Fbx, FBX7, PARK15" ENSG00000100225 "F-box protein 7" Q9Y3I1 22 32474676-32498829 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 263.7" "Cell type enhanced" "Detected in all" "Early spermatids: 332.1;Erythrocytes: 347.7;Late spermatids: 1098.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032113, HPA032114, CAB034296, HPA057352" Uncertain Supported Nucleoplasm,Cytosol NA NA 310000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 99 "Nucleoplasm, Cytosol" "CAB034296: , HPA032113: , HPA032114: , HPA057352: " "unprognostic (3.73e-3)" "unprognostic (2.44e-1)" "unprognostic (4.13e-1)" "unprognostic (2.35e-1)" "unprognostic (1.84e-2)" "unprognostic (4.73e-2)" "unprognostic (1.40e-1)" "unprognostic (1.66e-2)" "unprognostic (1.56e-2)" "unprognostic (7.07e-2)" "validated prognostic favorable (6.53e-8)" "validated prognostic favorable (1.97e-6)" "unprognostic (1.15e-2)" "unprognostic (1.35e-1)" "unprognostic (2.60e-1)" "unprognostic (4.01e-2)" "unprognostic (3.05e-2)" "unprognostic (6.11e-2)" "unprognostic (1.48e-1)" "unprognostic (9.20e-2)" "unprognostic (8.29e-2)" "unprognostic (6.64e-2)" "unprognostic (9.51e-2)" "unprognostic (5.87e-2)" "unprognostic (1.88e-3)" "unprognostic (3.97e-2)" "unprognostic (1.14e-1)" "unprognostic (4.63e-2)" "unprognostic (2.22e-1)" "unprognostic (2.62e-1)" "unprognostic (1.25e-1)" FBXO8 "FBS, FBX8" ENSG00000164117 "F-box protein 8" Q9NRD0 4 174236658-174283667 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 117.9;Syncytiotrophoblasts: 119.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002885 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 76: Non-specific - Metabolism" "Cluster 55: Non-specific - Transcription" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 108: Fibroblasts - ECM organization" 9 Nucleoplasm Cytosol "HPA002885: " "unprognostic (1.41e-2)" "unprognostic (3.25e-2)" "unprognostic (4.72e-3)" "unprognostic (2.97e-2)" "unprognostic (1.19e-1)" "unprognostic (3.02e-2)" "unprognostic (1.73e-2)" "unprognostic (1.58e-1)" "unprognostic (2.48e-3)" "unprognostic (9.13e-2)" "validated prognostic favorable (5.03e-9)" "validated prognostic favorable (1.58e-5)" "unprognostic (9.96e-2)" "unprognostic (7.06e-2)" "unprognostic (2.12e-3)" "unprognostic (2.92e-1)" "unprognostic (5.37e-2)" "unprognostic (1.03e-1)" "unprognostic (3.99e-2)" "unprognostic (4.93e-2)" "unprognostic (1.02e-3)" "unprognostic (3.66e-2)" "unprognostic (1.04e-1)" "unprognostic (1.20e-2)" "unprognostic (1.46e-1)" "unprognostic (1.77e-1)" "unprognostic (4.26e-2)" "unprognostic (1.29e-1)" "unprognostic (2.03e-1)" "unprognostic (1.71e-1)" "unprognostic (1.15e-1)" FBXO9 "FBX9, NY-REN-57" ENSG00000112146 "F-box protein 9" Q9UK97 6 53051991-53100873 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 296.4;Neutrophil progenitors: 383.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064246 Approved Centrosome NA NA "Cluster 41: Basophils - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 31: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 6 Centrosome "HPA064246: " "unprognostic (2.18e-1)" "unprognostic (1.05e-2)" "unprognostic (3.34e-1)" "unprognostic (3.31e-1)" "unprognostic (2.08e-1)" "unprognostic (1.15e-1)" "unprognostic (1.23e-1)" "unprognostic (3.87e-2)" "unprognostic (2.30e-2)" "unprognostic (1.69e-2)" "validated prognostic favorable (1.61e-4)" "validated prognostic favorable (5.60e-4)" "unprognostic (1.65e-2)" "unprognostic (8.73e-2)" "unprognostic (1.97e-2)" "unprognostic (6.88e-3)" "unprognostic (5.77e-1)" "unprognostic (2.30e-1)" "unprognostic (2.35e-2)" "unprognostic (5.07e-3)" "unprognostic (2.62e-1)" "unprognostic (2.12e-3)" "unprognostic (1.19e-1)" "unprognostic (5.39e-2)" "unprognostic (1.01e-1)" "unprognostic (1.01e-1)" "unprognostic (1.04e-3)" "unprognostic (7.45e-2)" "unprognostic (2.09e-1)" "unprognostic (5.77e-2)" "unprognostic (1.92e-1)" FBXW10 "C17orf1, C17orf1A, Fbw10, HREP, SM2SH2" ENSG00000171931 "F-box and WD repeat domain containing 10" Q5XX13 17 18744026-18779349 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "testis: 9.1" "Cell type enhanced" "Detected in some" "Early spermatids: 62.8;Late primary spermatocytes: 30.6;Late spermatids: 19.8;Respiratory ciliated cells: 9.1;Retinal ganglion cells: 7.7;Tuft cells: 11.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 3.7;liver cancer: 1.6" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA047457 Approved Nucleoplasm NA NA "Cluster 67: Testis - Mixed function" "Cluster 46: Brainstem - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 2 Nucleoplasm "HPA047457: " "unprognostic (3.01e-2)" "unprognostic (1.44e-2)" FBXW10B "CDRT1, FBXW10P1, HREP, SM25H2" ENSG00000241322 "F-box and WD repeat domain containing 10B" O95170 17 15565483-15619704 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "esophagus: 7.8;testis: 11.6" "Group enriched" "Detected in some" 4 "Early spermatids: 20.4;Ependymal cells: 5.2;Late primary spermatocytes: 19.3;Late spermatids: 10.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 11.3" "Stomach - Gastric mucous cells, Testis - Early spermatids" "HPA013332, HPA047457" Approved Nucleoplasm,Nucleoli NA NA "Cluster 39: Testis - Nuclear processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" "Nucleoplasm, Nucleoli" "HPA013332: , HPA047457: " "unprognostic (1.05e-1)" "unprognostic (9.75e-2)" "unprognostic (5.22e-2)" "unprognostic (6.63e-2)" "unprognostic (1.09e-2)" "unprognostic (6.87e-2)" "unprognostic (3.49e-2)" "unprognostic (3.76e-2)" "unprognostic (2.04e-1)" "unprognostic (8.39e-2)" "unprognostic (2.14e-2)" "unprognostic (6.90e-2)" "unprognostic (1.21e-1)" "unprognostic (3.04e-1)" "unprognostic (1.03e-1)" FBXW11 "BTRC2, BTRCP2, Fbw11, Fbw1b, FBXW1B, Hos, KIAA0696" ENSG00000072803 "F-box and WD repeat domain containing 11" Q9UKB1 5 171861549-172006873 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Host-virus interaction, Ubl conjugation pathway, Wnt signaling pathway" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072204 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 32: Basophils - Transcription" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 51: Secretory epithelial cells - Mixed function" 172 "Vesicles, Plasma membrane" Nucleoplasm "HPA072204: " "unprognostic (4.49e-2)" "unprognostic (2.86e-2)" "unprognostic (1.64e-1)" "unprognostic (2.90e-2)" "unprognostic (4.63e-2)" "unprognostic (3.91e-2)" "unprognostic (1.40e-1)" "unprognostic (1.07e-1)" "unprognostic (2.21e-1)" "unprognostic (7.48e-3)" "potential prognostic favorable (2.93e-9)" "unprognostic (9.18e-3)" "unprognostic (2.91e-1)" "unprognostic (2.08e-2)" "unprognostic (2.18e-1)" "unprognostic (3.40e-1)" "unprognostic (1.18e-2)" "unprognostic (4.84e-2)" "unprognostic (3.37e-1)" "unprognostic (4.51e-2)" "potential prognostic unfavorable (3.47e-6)" "unprognostic (9.79e-2)" "unprognostic (3.47e-1)" "unprognostic (6.66e-2)" "unprognostic (1.44e-1)" "unprognostic (2.95e-1)" "unprognostic (1.14e-1)" "unprognostic (2.65e-2)" "unprognostic (2.64e-1)" "unprognostic (1.51e-2)" "unprognostic (1.77e-2)" FBXW12 "Fbw12, FBXO35" ENSG00000164049 "F-box and WD repeat domain containing 12" Q6X9E4 3 48372219-48401259 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 8 "pancreas: 5.7" "Group enriched" "Detected in some" 5 "Epicardial cells: 50.0;Oocytes: 170.4" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "HPA037491, HPA037492" Uncertain Approved Vesicles,Cytosol NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 51: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 41: Oocytes - Oogenesis" 1 Cytosol Vesicles "HPA037491: , HPA037492: " FBXW2 "FBW2, Fwd2, Md6" ENSG00000119402 "F-box and WD repeat domain containing 2" Q9UKT8 9 120751978-120793416 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 304.5;Neutrophil progenitors: 302.2;Neutrophils: 229.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067878 Approved Approved Nucleoplasm NA NA "Cluster 41: Basophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 22 Nucleoplasm "HPA067878: " "unprognostic (2.21e-2)" "unprognostic (2.77e-2)" "unprognostic (1.57e-2)" "unprognostic (1.86e-1)" "unprognostic (1.00e-1)" "potential prognostic unfavorable (1.78e-5)" "unprognostic (1.93e-1)" "unprognostic (4.01e-1)" "unprognostic (2.99e-1)" "unprognostic (1.07e-2)" "potential prognostic favorable (4.96e-8)" "unprognostic (1.80e-3)" "unprognostic (4.70e-2)" "unprognostic (1.74e-2)" "unprognostic (6.65e-3)" "unprognostic (1.93e-1)" "unprognostic (5.47e-2)" "unprognostic (1.28e-2)" "unprognostic (1.31e-1)" "unprognostic (7.77e-2)" "unprognostic (8.35e-3)" "unprognostic (1.51e-1)" "unprognostic (8.01e-2)" "unprognostic (2.19e-2)" "unprognostic (4.80e-2)" "unprognostic (1.70e-1)" "unprognostic (2.62e-1)" "unprognostic (4.95e-2)" "unprognostic (1.59e-1)" "unprognostic (8.51e-2)" "unprognostic (1.73e-1)" FBXW4 "dactylin, Fbw4, SHFM3" ENSG00000107829 "F-box and WD repeat domain containing 4" P57775 10 101610664-101695295 "Disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway, Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043496 Approved Approved "Golgi apparatus" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 7: Non-specific - Transcription" 30 "Golgi apparatus" "HPA043496: " "unprognostic (9.94e-2)" "unprognostic (1.06e-1)" "unprognostic (2.86e-1)" "unprognostic (3.04e-2)" "unprognostic (3.29e-2)" "unprognostic (3.60e-2)" "unprognostic (3.85e-1)" "unprognostic (7.56e-2)" "unprognostic (8.76e-2)" "unprognostic (9.46e-2)" "unprognostic (3.28e-3)" "unprognostic (1.18e-2)" "unprognostic (4.41e-3)" "unprognostic (1.49e-2)" "unprognostic (1.54e-1)" "unprognostic (3.55e-3)" "unprognostic (2.44e-1)" "unprognostic (9.84e-2)" "unprognostic (2.03e-1)" "unprognostic (3.25e-1)" "unprognostic (5.02e-2)" "potential prognostic favorable (1.24e-4)" "unprognostic (2.54e-2)" "unprognostic (1.38e-1)" "unprognostic (2.71e-1)" "unprognostic (3.53e-1)" "unprognostic (1.07e-1)" "unprognostic (9.57e-2)" "unprognostic (3.82e-2)" "unprognostic (9.58e-2)" "unprognostic (7.33e-3)" FBXW5 "DKFZP434B205, Fbw5, MGC20962" ENSG00000159069 "F-box and WD repeat domain containing 5" Q969U6 9 136940435-136944738 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 219.8" "Cell type enriched" "Detected in many" 5 "Late spermatids: 3413.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046615 Approved Approved Mitochondria No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 67: Testis - Mixed function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 89 Mitochondria "HPA046615: " "unprognostic (1.16e-1)" "unprognostic (1.71e-2)" "unprognostic (3.81e-2)" "unprognostic (2.75e-3)" "unprognostic (4.08e-1)" "unprognostic (2.26e-1)" "unprognostic (2.38e-1)" "unprognostic (2.54e-1)" "unprognostic (2.69e-1)" "unprognostic (1.51e-2)" "potential prognostic favorable (1.88e-7)" "unprognostic (2.97e-1)" "unprognostic (3.45e-2)" "unprognostic (7.19e-3)" "unprognostic (1.34e-1)" "unprognostic (2.57e-2)" "unprognostic (4.63e-1)" "unprognostic (9.97e-3)" "unprognostic (2.35e-1)" "unprognostic (2.02e-1)" "unprognostic (3.43e-2)" "unprognostic (4.84e-2)" "unprognostic (1.40e-1)" "unprognostic (5.00e-2)" "unprognostic (9.20e-2)" "unprognostic (1.04e-1)" "unprognostic (1.41e-1)" "unprognostic (6.29e-2)" "unprognostic (9.68e-2)" "unprognostic (1.20e-1)" "unprognostic (1.79e-1)" FBXW7 "AGO, CDC4, FBW7, FBX30, FBXW6, FLJ11071, SEL-10, SEL10" ENSG00000109670 "F-box and WD repeat domain containing 7" Q969H0 4 152320544-152536092 "Cancer-related genes, Predicted intracellular proteins" "Biological rhythms, DNA damage, DNA repair, Host-virus interaction, Ubl conjugation pathway" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 58.3;skin 1: 57.7" "Cell type enhanced" "Detected in all" "Neutrophils: 1270.6;Plasma cells: 1258.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 20.9" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013793, CAB029987" Supported Supported Nucleoplasm,Vesicles NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 2: Non-specific - Mixed function" "Cluster 34: Non-specific - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 44: Plasma cells - Antibody production & secretion" 188 "Nucleoplasm, Vesicles" "CAB013793: , CAB029987: " "unprognostic (1.85e-1)" "unprognostic (1.34e-1)" "unprognostic (5.63e-2)" "unprognostic (1.45e-1)" "unprognostic (1.22e-2)" "unprognostic (6.82e-2)" "unprognostic (1.25e-1)" "unprognostic (5.08e-1)" "unprognostic (1.59e-2)" "potential prognostic unfavorable (2.30e-4)" "unprognostic (5.94e-3)" "unprognostic (1.68e-3)" "unprognostic (1.58e-1)" "unprognostic (2.46e-1)" "unprognostic (2.72e-2)" "unprognostic (4.55e-1)" "unprognostic (6.57e-2)" "unprognostic (6.23e-2)" "unprognostic (5.91e-1)" "unprognostic (4.03e-2)" "unprognostic (1.26e-1)" "unprognostic (1.36e-1)" "unprognostic (8.60e-3)" "unprognostic (1.48e-1)" "unprognostic (2.43e-2)" "unprognostic (1.86e-2)" "unprognostic (7.83e-2)" "unprognostic (2.71e-1)" "unprognostic (3.17e-1)" "unprognostic (2.50e-1)" "unprognostic (1.76e-1)" FBXW8 "FBW6, FBW8, FBX29, FBXO29" ENSG00000174989 "F-box and WD repeat domain containing 8" Q8N3Y1 12 116910950-117031148 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 347.1;Choroid plexus epithelial cells: 236.0;Lactotrophs: 196.0;Somatotrophs: 232.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038850, HPA038851" Supported Supported Cytosol NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 17: Choroid plexus - Cilium" "Cluster 38: Non-specific - Transcription" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 21 Cytosol "HPA038850: , HPA038851: " "unprognostic (3.51e-2)" "unprognostic (4.11e-2)" "unprognostic (1.17e-1)" "unprognostic (1.84e-2)" "unprognostic (7.72e-3)" "unprognostic (6.18e-3)" "unprognostic (2.51e-1)" "unprognostic (2.60e-2)" "unprognostic (1.40e-2)" "potential prognostic unfavorable (4.90e-4)" "unprognostic (2.53e-3)" "unprognostic (1.23e-1)" "unprognostic (4.21e-1)" "unprognostic (1.24e-2)" "unprognostic (2.21e-2)" "unprognostic (7.83e-2)" "unprognostic (9.49e-3)" "unprognostic (5.61e-2)" "unprognostic (4.43e-2)" "unprognostic (6.74e-2)" "unprognostic (3.18e-2)" "unprognostic (1.89e-1)" "unprognostic (9.42e-2)" "unprognostic (9.43e-2)" "unprognostic (1.48e-2)" "unprognostic (4.93e-2)" "unprognostic (4.67e-2)" "unprognostic (4.39e-1)" "unprognostic (5.00e-2)" "unprognostic (2.01e-2)" "unprognostic (7.55e-3)" FBXW9 "Fbw9, MEC-15, MGC10870" ENSG00000132004 "F-box and WD repeat domain containing 9" Q5XUX1 19 12688053-12696631 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 75.6;Epididymal efferent duct ciliated cells: 59.6;Fallopian tube ciliated cells: 88.7;Late primary spermatocytes: 39.8;Megakaryocytes: 123.6;Respiratory ciliated cells: 77.1" "Cell type enhanced" "Detected in all" "ependymal cell: 26.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042087 Approved Approved Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 23: Non-specific - Transcription" "Cluster 107: Ciliated cells - Cilia assembly & function" 5 Cytosol "HPA042087: " "unprognostic (1.79e-1)" "unprognostic (1.05e-1)" "unprognostic (7.06e-2)" "unprognostic (8.36e-2)" "unprognostic (1.83e-1)" "unprognostic (2.42e-2)" "unprognostic (2.63e-1)" "unprognostic (1.95e-1)" "unprognostic (2.87e-3)" "unprognostic (3.93e-2)" "unprognostic (2.44e-2)" "unprognostic (7.35e-2)" "unprognostic (1.11e-2)" "potential prognostic unfavorable (3.87e-5)" "unprognostic (1.22e-3)" "unprognostic (1.15e-1)" "unprognostic (7.50e-2)" "unprognostic (6.40e-3)" "unprognostic (5.35e-2)" "unprognostic (1.54e-1)" "unprognostic (1.40e-1)" "unprognostic (8.93e-2)" "unprognostic (1.24e-1)" "unprognostic (5.12e-2)" "unprognostic (1.61e-3)" "potential prognostic favorable (2.49e-5)" "potential prognostic unfavorable (5.22e-4)" "unprognostic (1.24e-2)" "unprognostic (3.70e-2)" "unprognostic (8.77e-2)" "unprognostic (1.83e-1)" FCAMR "CD351, FCA/MR, Fcalpha/muR, FKSG87" ENSG00000162897 "Fc alpha and mu receptor" Q8WWV6 1 206957965-206970625 "CD markers, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "kidney: 35.6;lymphoid tissue: 24.5" "Group enriched" "Detected in some" 5 "Paneth cells: 3.9;Proximal tubule cells: 10.9" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney Renal Papillary Cell Carcinoma (TCGA): 20.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA056505 Enhanced NA NA 1500000 "Cluster 72: Kidney - Transmembrane transport" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 88: Proximal tubular cells - Transmembrane transport" "HPA056505: " "unprognostic (1.50e-1)" "unprognostic (1.69e-3)" "unprognostic (1.88e-2)" "unprognostic (1.85e-1)" "unprognostic (6.26e-3)" "unprognostic (3.47e-3)" "unprognostic (3.37e-1)" "unprognostic (8.60e-2)" FCAR "CD89, FcalphaR, FcalphaRI" ENSG00000186431 "Fc alpha receptor" P24071 19 54874235-54891420 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "IgA-binding protein, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 24.7;lung: 10.7;lymphoid tissue: 14.5" "Cell type enhanced" "Detected in some" "Microglia: 3.1;monocytes: 6.7;Neutrophil progenitors: 7.3;Neutrophils: 20.0" "Group enriched" "Detected in some" 4 "central nervous system macrophage: 5.4;leukocyte: 6.8" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "classical monocyte: 1.3;neutrophil: 4.1" "Group enriched" "Detected in many" 27 "granulocytes: 4.1;monocytes: 1.3" "Not detected" "Not detected" "Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophils_2, Pituitary gland - Neutrophils, Skeletal muscle - Neutrophils, Spleen - Neutrophils_2, Stomach - Neutrophils, Thyroid gland - Neutrophils" "Not detected" "Not detected" HPA014050 Approved Supported "Plasma membrane" "Intracellular and membrane" Receptor NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 1 "Plasma membrane" "HPA014050: " "unprognostic (1.77e-1)" "unprognostic (2.25e-2)" "unprognostic (2.14e-2)" FCER1A "FCE1A, FcepsilonRIalpha, FCERIA" ENSG00000179639 "Fc epsilon receptor Ia" P12319 1 159289714-159308224 "FDA approved drug targets, Predicted membrane proteins" "IgE-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 35.1" "Cell type enriched" "Detected in some" 7 "cDC: 1200.2" "Group enriched" "Detected in some" 4 "central nervous system macrophage: 1.5;leukocyte: 3.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 8 "basophil: 21795.4" "Lineage enriched" "Detected in all" 8 "granulocytes: 21795.4" "Group enriched" "Detected in some" 116 "Leukemia: 39.1;lymphoma: 10.8" "Skin - Langerhans cells" "Not detected" "Not detected" "Region enriched" "Detected in single" 8 "spinal cord: 1.0" "CAB022102, HPA036051, CAB055526" Approved NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 55: Breast - Lactation" "Cluster 47: Leukemia - Hemostasis" "Cluster 82: Dendritic cells - Antigen presentation" 8 "CAB022102: , CAB055526: , HPA036051: " "unprognostic (1.06e-1)" "unprognostic (8.32e-3)" "unprognostic (8.26e-3)" "unprognostic (5.73e-2)" "unprognostic (2.25e-2)" "unprognostic (1.49e-2)" "unprognostic (3.06e-1)" "unprognostic (2.26e-3)" "validated prognostic favorable (4.30e-9)" "validated prognostic favorable (5.63e-6)" "unprognostic (6.82e-2)" "unprognostic (7.44e-2)" "unprognostic (3.35e-2)" "unprognostic (6.85e-3)" "unprognostic (2.07e-1)" "unprognostic (1.95e-1)" "unprognostic (3.42e-1)" "unprognostic (3.55e-2)" "unprognostic (7.99e-2)" "unprognostic (1.39e-1)" "unprognostic (1.75e-1)" "unprognostic (3.65e-1)" "unprognostic (1.48e-1)" "unprognostic (3.09e-1)" "unprognostic (2.33e-2)" "unprognostic (9.56e-2)" "unprognostic (4.20e-1)" "unprognostic (3.98e-1)" FCER1G FcepsilonRIgamma ENSG00000158869 "Fc epsilon receptor Ig" P30273 1 161215234-161220699 "FDA approved drug targets, Predicted membrane proteins" "Immunity, Innate immunity" "IgE-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 416.9;lymphoid tissue: 448.7" "Cell type enhanced" "Detected in many" "cDC: 1062.3;Hofbauer cells: 2845.3;Kupffer cells: 2554.1;Macrophages: 1050.3;Mast cells: 778.2;Megakaryocytes: 1316.7;monocytes: 1400.6;Neutrophil progenitors: 491.8;Neutrophils: 3045.3;NK-cells: 482.7;pDCs: 650.1;Platelets: 917.9" "Group enriched" "Detected in some" 29 "central nervous system macrophage: 94.5;leukocyte: 60.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 7025.3" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Leukemia: 55.5;lymphoma: 18.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022108, HPA026872" Supported NA NA 77000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 5 "CAB022108: , HPA026872: " "unprognostic (2.13e-1)" "unprognostic (1.10e-2)" "unprognostic (7.61e-2)" "unprognostic (1.06e-1)" "unprognostic (7.52e-2)" "unprognostic (8.27e-2)" "unprognostic (1.94e-2)" "unprognostic (5.02e-2)" "unprognostic (1.50e-1)" "unprognostic (4.65e-1)" "potential prognostic unfavorable (7.40e-4)" "unprognostic (2.68e-1)" "unprognostic (2.06e-1)" "unprognostic (2.25e-3)" "unprognostic (5.09e-2)" "unprognostic (1.19e-1)" "unprognostic (2.91e-2)" "unprognostic (1.45e-1)" "unprognostic (2.43e-1)" "unprognostic (1.55e-1)" "unprognostic (3.13e-1)" "unprognostic (6.46e-2)" "unprognostic (9.97e-2)" "unprognostic (2.03e-2)" "unprognostic (1.79e-3)" "unprognostic (3.07e-1)" "unprognostic (2.01e-1)" "unprognostic (2.52e-2)" "unprognostic (1.00e-2)" "unprognostic (4.64e-2)" "unprognostic (2.90e-1)" FCER2 "CD23, CD23A, CLEC4J, FCE2, FcepsilonRII, FCErII" ENSG00000104921 "Fc epsilon receptor II" P06734 19 7688758-7702146 "Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "IgE-binding protein, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "lymphoid tissue: 39.5" "Cell type enriched" "Detected in some" 18 "B-cells: 115.8" "Cell type enriched" "Detected in single" 5 "leukocyte: 2.7" "Cancer enhanced" "Detected in many" "Pancreatic Adenocarcinoma (TCGA): 4.5" "Region enhanced" "Detected in single" "cerebral cortex: 2.8" "Group enriched" "Detected in many" 24 "memory B-cell: 201.7;naive B-cell: 497.3" "Lineage enriched" "Detected in many" 34 "B-cells: 497.3" "Group enriched" "Detected in some" 16 "Leukemia: 49.4;lymphoma: 34.1;Myeloma: 41.1" "Liver - T-cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in single" "Not detected" "Not detected" "CAB002624, HPA008928, HPA067430" Enhanced "Secreted to blood" Receptor NA NA 81000 "Cluster 18: Non-specific - Translation" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 55: Lymphoma - Immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 1 "CAB002624: , HPA008928: , HPA067430: " "unprognostic (2.76e-1)" "unprognostic (3.12e-3)" "unprognostic (3.71e-3)" "unprognostic (2.52e-1)" "potential prognostic favorable (9.66e-4)" "unprognostic (1.79e-1)" "unprognostic (6.24e-2)" "unprognostic (2.13e-1)" "unprognostic (1.26e-1)" FCF1 "Bka, C14orf111, CGI-35, UTP24" ENSG00000119616 "FCF1 rRNA-processing protein" Q9Y324 14 74713144-74738620 "Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 109.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046681 Approved Approved Nucleoplasm NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 75: Ovary - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 93: Hepatocytes - Bile production & excretion" 12 Nucleoplasm "HPA046681: " "unprognostic (5.12e-2)" "unprognostic (7.78e-2)" "unprognostic (1.89e-1)" "unprognostic (1.43e-3)" "unprognostic (2.27e-1)" "unprognostic (1.67e-1)" "unprognostic (1.14e-1)" "unprognostic (9.07e-2)" "unprognostic (2.99e-2)" "unprognostic (6.64e-3)" "potential prognostic favorable (6.26e-6)" "unprognostic (2.42e-2)" "unprognostic (1.26e-1)" "potential prognostic unfavorable (6.39e-4)" "unprognostic (2.34e-3)" "unprognostic (2.02e-2)" "unprognostic (2.68e-3)" "unprognostic (2.42e-1)" "unprognostic (1.06e-1)" "unprognostic (3.14e-2)" "potential prognostic unfavorable (1.35e-4)" "potential prognostic unfavorable (7.07e-5)" "unprognostic (2.28e-3)" "unprognostic (2.60e-1)" "unprognostic (1.51e-2)" "unprognostic (2.44e-2)" "unprognostic (6.97e-2)" "unprognostic (8.44e-2)" "unprognostic (2.99e-1)" "unprognostic (3.11e-2)" "unprognostic (3.02e-2)" FCGBP "FC(GAMMA)BP, FcgammaBP" ENSG00000275395 "Fc gamma binding protein" 19 39863323-39934626 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 192.6;salivary gland: 87.6;thyroid gland: 93.6" "Cell type enriched" "Detected in many" 10 "Goblet cells: 10323.0" "Cell type enriched" "Detected in many" 4 "central nervous system macrophage: 76.5" "Cancer enhanced" "Detected in all" "Colon Adenocarcinoma (TCGA): 108.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Gastric cancer: 12.2" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Heart muscle - Macrophages, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Macrophages, Pituitary gland - Macrophages, Skeletal muscle - Macrophages, Skin - Langerhans cells" "HPA003517, HPA003564" Enhanced Approved "Golgi apparatus,Plasma membrane,Cytokinetic bridge" "Secreted in other tissues" Yes NA "Cluster 77: Intestine - Digestion" "Cluster 12: Non-specific - Vasculature" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 70: Intestinal goblet cells - Mucin production" "Plasma membrane" "Golgi apparatus, Cytokinetic bridge" "HPA003517: , HPA003564: " "unprognostic (6.84e-2)" "unprognostic (9.14e-3)" "unprognostic (1.46e-1)" "unprognostic (2.67e-1)" "unprognostic (1.10e-3)" "unprognostic (2.16e-2)" "unprognostic (3.07e-2)" "potential prognostic favorable (1.22e-6)" "unprognostic (5.49e-3)" "unprognostic (8.03e-2)" "unprognostic (5.52e-1)" "unprognostic (3.89e-2)" "potential prognostic unfavorable (1.12e-5)" "unprognostic (7.45e-2)" "unprognostic (9.40e-3)" "unprognostic (2.25e-1)" "unprognostic (1.54e-1)" "potential prognostic unfavorable (5.05e-5)" "unprognostic (2.23e-1)" "unprognostic (9.67e-3)" "unprognostic (7.08e-3)" "unprognostic (8.98e-2)" "unprognostic (7.54e-2)" "unprognostic (1.42e-1)" "unprognostic (3.65e-1)" "potential prognostic unfavorable (1.61e-4)" "unprognostic (1.96e-2)" FCGR1A "CD64, CD64A, FCG1, FcgammaRI, FcgammaRIa, FCGR1" ENSG00000150337 "Fc gamma receptor Ia" P12314 1 149782671-149791675 "CD markers, Essential proteins, FDA approved drug targets, Predicted membrane proteins" "Immunity, Innate immunity" "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 95.0" "Cell type enhanced" "Detected in some" "Early spermatids: 30.2;Epididymal principal cells: 55.3;Hofbauer cells: 350.0;Kupffer cells: 73.8;Late spermatids: 88.1;Macrophages: 50.2;monocytes: 61.3;Neutrophils: 80.6" "Cell type enriched" "Detected in single" 27 "central nervous system macrophage: 24.2" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 65.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 137.1;intermediate monocyte: 57.3;myeloid DC: 37.3;neutrophil: 98.7" "Group enriched" "Detected in many" 55 "dendritic cells: 37.3;granulocytes: 98.7;monocytes: 137.1" "Cancer enriched" "Detected in single" 27 "Leukemia: 25.7" "Adipose visceral - Macrophages, Adrenal gland - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Lung - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Stomach - Macrophages, Testis - Late spermatids, Thyroid gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026910 Uncertain "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 22: Epididymis - Mixed function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 21 Vesicles "Golgi apparatus, Plasma membrane" "HPA026910: " "unprognostic (5.28e-2)" "unprognostic (5.91e-2)" "unprognostic (1.22e-1)" "unprognostic (1.68e-2)" "unprognostic (3.77e-2)" "unprognostic (3.53e-2)" "unprognostic (1.74e-2)" "unprognostic (3.24e-2)" "unprognostic (8.62e-2)" "unprognostic (3.13e-1)" "unprognostic (5.95e-3)" "unprognostic (1.16e-1)" "unprognostic (1.87e-1)" "unprognostic (2.51e-2)" "unprognostic (5.11e-2)" "unprognostic (1.49e-1)" "unprognostic (1.57e-2)" "unprognostic (4.07e-2)" "unprognostic (2.05e-1)" "unprognostic (9.91e-2)" "unprognostic (3.07e-1)" "unprognostic (1.57e-1)" "unprognostic (4.21e-1)" "unprognostic (1.21e-1)" "unprognostic (2.77e-2)" "unprognostic (2.69e-2)" "unprognostic (6.35e-2)" "unprognostic (3.73e-2)" "unprognostic (7.51e-3)" "unprognostic (5.60e-2)" "unprognostic (1.35e-1)" FCGR2A "CD32, CD32A, CDw32, Fc-gamma-RIIa, FCG2, FcgammaRIIa, FCGR2, FCGR2A1, IGFR2" ENSG00000143226 "Fc gamma receptor IIa" P12318 1 161505430-161524013 "CD markers, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Immunity "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 113.4;placenta: 126.7" "Cell type enriched" "Detected in some" 4 "Neutrophils: 452.3" "Group enriched" "Detected in some" 31 "central nervous system macrophage: 82.9;leukocyte: 22.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 2531.1" "Lineage enriched" "Detected in many" 6 "granulocytes: 2531.1" "Cancer enriched" "Detected in some" 5 "Leukemia: 40.8" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Neutrophils, Lung - Neutrophils_2, Pancreas - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Spleen - Neutrophils_2, Stomach - Macrophages, Thyroid gland - Macrophages" "HPA010718, HPA010776, HPA014730" Supported Supported "Golgi apparatus,Plasma membrane" NA NA 34000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 24: Neutrophils - Innate immunity signal integration" 4 "Plasma membrane" "Golgi apparatus" "HPA010718: , HPA010776: , HPA014730: " "unprognostic (2.04e-1)" "unprognostic (1.41e-2)" "unprognostic (1.23e-1)" "unprognostic (5.86e-2)" "unprognostic (2.23e-1)" "unprognostic (1.57e-2)" "unprognostic (6.11e-2)" "unprognostic (5.06e-3)" "unprognostic (3.20e-2)" "unprognostic (2.79e-1)" "unprognostic (1.68e-2)" "unprognostic (2.65e-1)" "unprognostic (9.49e-2)" "unprognostic (1.31e-2)" "unprognostic (1.51e-1)" "unprognostic (8.99e-2)" "unprognostic (2.18e-3)" "unprognostic (3.85e-3)" "unprognostic (9.64e-2)" "unprognostic (1.02e-3)" "unprognostic (1.90e-2)" "unprognostic (3.68e-2)" "unprognostic (7.81e-2)" "unprognostic (1.77e-1)" "unprognostic (4.83e-3)" "unprognostic (9.63e-2)" "unprognostic (1.18e-1)" "unprognostic (2.83e-2)" "unprognostic (2.36e-2)" "unprognostic (1.91e-1)" "unprognostic (4.06e-1)" FCGR2B "CD32, CD32B, FCG2, FcgammaRIIb, FCGR2, FcGRIIB" ENSG00000072694 "Fc gamma receptor IIb" P31994 1 161663143-161678654 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" "Host-virus interaction" "IgG-binding protein, Receptor" "Cancer-related genes, FDA approved drug targets, Proto-oncogene, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 10 "placenta: 378.4" "Cell type enhanced" "Detected in some" "B-cells: 56.2;cDC: 237.0;Macrophages: 116.7;monocytes: 39.5;Neutrophils: 19.1;Plasma cells: 72.4;Vascular endothelial cells: 48.5" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 8.4;leukocyte: 3.7;vascular associated smooth muscle cell: 1.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 328.6;memory B-cell: 203.6" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Leukemia: 10.4;lymphoma: 25.1" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Liver - Sinusoid Endothelial cells, Minor Salivary Gland - Macrophages, Skeletal muscle - Macrophages, Spleen - B-cells (Spleen), Testis - Macrophages, Thyroid gland - Macrophages" "CAB007796, HPA014730" Enhanced NA NA "Cluster 32: Basophils - Transcription" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 8: Immune cells - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 82: Dendritic cells - Antigen presentation" 8 "CAB007796: , HPA014730: " "unprognostic (4.29e-1)" "unprognostic (8.73e-2)" "unprognostic (2.89e-1)" "unprognostic (3.90e-2)" "unprognostic (1.46e-1)" "unprognostic (9.19e-2)" "unprognostic (1.84e-3)" "unprognostic (2.43e-3)" "unprognostic (9.25e-3)" "unprognostic (1.72e-1)" "unprognostic (2.71e-2)" "unprognostic (2.52e-2)" "unprognostic (9.35e-3)" "unprognostic (1.47e-1)" "unprognostic (6.11e-2)" "unprognostic (7.35e-3)" "unprognostic (9.11e-3)" "unprognostic (1.22e-1)" "unprognostic (5.90e-2)" "unprognostic (3.96e-3)" "unprognostic (2.74e-1)" "unprognostic (6.03e-2)" "unprognostic (2.48e-2)" "unprognostic (4.38e-1)" "unprognostic (3.28e-2)" "unprognostic (9.93e-2)" "unprognostic (2.19e-1)" "unprognostic (5.77e-2)" "unprognostic (4.86e-2)" "unprognostic (2.59e-1)" "unprognostic (1.55e-1)" FCGR2C "CD32C, Fc-gamma-RIIc, FcgammaRIIc, hFcRII-C" ENSG00000244682 "Fc gamma receptor IIc (gene/pseudogene)" 1 161581339-161605662 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 11 "placenta: 26.6" "Group enriched" "Detected in some" 5 "cDC: 22.8;Macrophages: 28.6;Microglia: 13.2;monocytes: 15.5" "Group enriched" "Detected in some" 23 "central nervous system macrophage: 37.4;leukocyte: 23.4" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 7.4" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in single" "Leukemia: 1.4" "Adipose subcutaneous - Macrophages, Adrenal gland - Macrophages, Skeletal muscle - Macrophages" "HPA010718, HPA010776, HPA014730" Uncertain Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 8: Immune cells - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" "Plasma membrane" "Golgi apparatus" "HPA010718: , HPA010776: , HPA014730: " FCGR3A "CD16, CD16a, FCG3, FcgammaRIIIa, FCGR3, FcGRIIIA" ENSG00000203747 "Fc gamma receptor IIIa" P08637 1 161541759-161550968 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" Immunity "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 196.4;lymphoid tissue: 285.0" "Cell type enriched" "Detected in some" 5 "Kupffer cells: 1731.1" "Group enriched" "Detected in some" 73 "central nervous system macrophage: 8.0;leukocyte: 6.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "intermediate monocyte: 1806.3;non-classical monocyte: 4107.1" "Lineage enriched" "Detected in all" 6 "monocytes: 4107.1" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Spleen - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid gland - Macrophages" "CAB032435, HPA055431" Supported "Secreted to blood" Receptor NA NA 260000000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 4 "CAB032435: , HPA055431: " "unprognostic (1.54e-1)" "unprognostic (6.90e-2)" "unprognostic (2.67e-1)" "unprognostic (6.27e-2)" "unprognostic (8.73e-2)" "unprognostic (6.79e-2)" "unprognostic (2.89e-2)" "unprognostic (6.36e-2)" "unprognostic (3.07e-1)" "unprognostic (1.24e-1)" "unprognostic (3.02e-2)" "unprognostic (2.89e-1)" "unprognostic (1.16e-2)" "unprognostic (3.05e-2)" "unprognostic (2.18e-1)" "unprognostic (3.46e-1)" "unprognostic (4.24e-3)" "unprognostic (3.67e-2)" "unprognostic (3.44e-1)" "unprognostic (2.90e-2)" "unprognostic (1.39e-1)" "unprognostic (9.13e-3)" "unprognostic (3.31e-2)" "unprognostic (2.98e-1)" "unprognostic (3.55e-2)" "unprognostic (2.45e-2)" "unprognostic (2.53e-1)" "unprognostic (9.66e-2)" "unprognostic (6.55e-2)" "unprognostic (2.44e-2)" "unprognostic (4.57e-2)" FCGR3B "CD16, CD16b, FCG3, FcgammaRIIIb, FCGR3, FcRIIIb" ENSG00000162747 "Fc gamma receptor IIIb" O75015 1 161623196-161631963 "CD markers, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 31.0;lymphoid tissue: 77.5" "Cell type enriched" "Detected in some" 21 "Neutrophils: 41.4" "Group enriched" "Detected in some" 23 "central nervous system macrophage: 2.1;leukocyte: 2.6" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 6 "cerebral cortex: 11.0;pons: 4.2" "Immune cell enriched" "Detected in many" 356 "neutrophil: 6077.6" "Lineage enriched" "Detected in many" 356 "granulocytes: 6077.6" "Not detected" "Not detected" "Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Pituitary gland - Neutrophils, Skeletal muscle - Neutrophils, Spleen - Neutrophils_2, Stomach - Neutrophils, Thyroid gland - Neutrophils" "Secreted to blood" Receptor NA NA 260000000 "Cluster 4: Neutrophils - Degranulation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 16 "unprognostic (9.39e-3)" "unprognostic (1.59e-1)" "unprognostic (2.46e-1)" "unprognostic (1.08e-1)" "unprognostic (8.14e-2)" "unprognostic (1.31e-1)" "unprognostic (2.27e-1)" "unprognostic (2.06e-3)" "unprognostic (7.70e-2)" "unprognostic (5.61e-2)" "unprognostic (9.38e-3)" "unprognostic (8.82e-2)" "unprognostic (3.26e-2)" "potential prognostic favorable (1.48e-4)" "unprognostic (1.44e-1)" "unprognostic (2.08e-1)" "unprognostic (8.95e-2)" "unprognostic (7.10e-2)" "unprognostic (1.20e-1)" "unprognostic (1.03e-1)" "unprognostic (6.78e-2)" "unprognostic (1.21e-2)" "unprognostic (1.95e-1)" "unprognostic (1.94e-1)" "unprognostic (5.97e-2)" "unprognostic (7.81e-2)" FCGRT "FcgammaRn, FcRn" ENSG00000104870 "Fc gamma receptor and transporter" P55899 19 49506816-49526428 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 600.5;Enteric stem cells: 525.3;Enteric transient amplifying cells: 572.7;Enterocytes: 1575.5;Hofbauer cells: 2332.4;Kupffer cells: 1472.8;Macrophages: 605.0;Paneth cells: 584.0" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 118.2;fibroblast: 65.1;pericyte: 58.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 2360.0" "Group enriched" "Detected in all" 17 "dendritic cells: 924.4;granulocytes: 2360.0;monocytes: 1367.7" "Cancer enhanced" "Detected in all" "Bone cancer: 261.3" "Adipose subcutaneous - Macrophages, Adrenal gland - Macrophages, Liver - Hepatocytes, Minor Salivary Gland - Macrophages, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012122, HPA015130" Uncertain NA NA 2800000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 28: Liver & Adrenal gland - Secretion" "Cluster 8: Immune cells - Immune response" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 34 "HPA012122: , HPA015130: " "potential prognostic favorable (8.13e-4)" "unprognostic (5.52e-2)" "unprognostic (1.20e-1)" "unprognostic (9.80e-2)" "unprognostic (1.51e-1)" "unprognostic (1.58e-1)" "unprognostic (2.43e-2)" "potential prognostic unfavorable (5.47e-4)" "unprognostic (2.31e-1)" "unprognostic (3.03e-1)" "potential prognostic favorable (1.19e-8)" "unprognostic (9.39e-3)" "potential prognostic favorable (1.88e-4)" "unprognostic (6.20e-2)" "unprognostic (2.67e-2)" "potential prognostic favorable (9.33e-6)" "unprognostic (1.33e-1)" "unprognostic (1.17e-1)" "unprognostic (1.03e-1)" "unprognostic (1.19e-1)" "unprognostic (1.69e-1)" "unprognostic (1.91e-1)" "potential prognostic favorable (3.67e-4)" "unprognostic (9.36e-2)" "unprognostic (8.29e-2)" "unprognostic (3.60e-1)" "unprognostic (2.49e-2)" "unprognostic (1.30e-1)" "unprognostic (5.12e-2)" "unprognostic (1.62e-2)" "unprognostic (2.36e-1)" FCHO1 KIAA0290 ENSG00000130475 "FCH and mu domain containing endocytic adaptor 1" O14526 19 17747718-17788568 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Endocytosis "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.8;lymphoid tissue: 14.9;skin 1: 20.2" "Cell type enhanced" "Detected in many" "B-cells: 29.3;cDC: 42.5;Innate lymphoid cells: 26.4;Microglia: 41.0;Neutrophils: 55.6;Oligodendrocytes: 70.5;pDCs: 43.0;Platelets: 25.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 7 "Leukemia: 23.4;lymphoma: 29.2;Myeloma: 22.3" "Adipose subcutaneous - Macrophages, Colon - T-cells, Kidney - T-cells, Prostate - T-cells, Skin - Keratinocyte (granular), Testis - Spermatogonia, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041653, HPA062981" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 7 Nucleoplasm Cytosol "HPA041653: , HPA062981: " "unprognostic (1.79e-2)" "unprognostic (1.87e-1)" "unprognostic (8.97e-2)" "unprognostic (9.16e-2)" "unprognostic (4.81e-2)" "unprognostic (5.80e-2)" "unprognostic (1.76e-2)" "unprognostic (7.46e-2)" "unprognostic (3.40e-2)" "unprognostic (2.14e-2)" "potential prognostic unfavorable (8.66e-7)" "unprognostic (1.13e-2)" "unprognostic (4.00e-2)" "unprognostic (1.32e-2)" "unprognostic (1.65e-1)" "unprognostic (1.25e-1)" "unprognostic (9.61e-2)" "unprognostic (1.10e-1)" "unprognostic (7.38e-2)" "unprognostic (1.66e-2)" "unprognostic (1.31e-1)" "unprognostic (1.69e-2)" "unprognostic (2.53e-1)" "unprognostic (2.02e-2)" "potential prognostic favorable (1.81e-4)" "unprognostic (4.92e-2)" "unprognostic (3.65e-1)" "unprognostic (5.82e-3)" "unprognostic (2.57e-1)" "unprognostic (1.55e-1)" "unprognostic (3.71e-2)" FCHO2 ENSG00000157107 "FCH and mu domain containing endocytic adaptor 2" Q0JRZ9 5 72956041-73090522 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 345.8;Esophageal apical cells: 767.1;Kupffer cells: 390.5" "Cell type enhanced" "Detected in all" "endothelial cell: 414.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 19.4;neutrophil: 20.7" "Group enriched" "Detected in many" 9 "granulocytes: 20.7;monocytes: 6.6" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037685, HPA037686, HPA077850" Enhanced Approved Vesicles,Centrosome,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 22 Centrosome "Vesicles, Cytosol" "HPA037685: , HPA037686: , HPA077850: " "potential prognostic favorable (4.05e-4)" "unprognostic (9.49e-2)" "unprognostic (4.26e-1)" "unprognostic (6.48e-2)" "unprognostic (2.05e-1)" "unprognostic (1.50e-1)" "unprognostic (4.82e-1)" "unprognostic (1.12e-1)" "potential prognostic favorable (1.55e-4)" "unprognostic (2.78e-3)" "potential prognostic favorable (3.25e-9)" "unprognostic (2.17e-3)" "unprognostic (3.36e-3)" "unprognostic (1.00e-1)" "unprognostic (1.81e-2)" "unprognostic (1.46e-1)" "unprognostic (4.71e-2)" "unprognostic (1.15e-2)" "unprognostic (4.73e-2)" "unprognostic (2.29e-2)" "unprognostic (5.08e-2)" "unprognostic (8.86e-3)" "unprognostic (1.43e-2)" "unprognostic (2.59e-1)" "unprognostic (5.95e-3)" "unprognostic (4.94e-3)" "unprognostic (7.89e-2)" "unprognostic (1.61e-1)" "unprognostic (1.16e-1)" "unprognostic (8.87e-2)" "unprognostic (9.61e-2)" FCHSD1 FLJ00007 ENSG00000197948 "FCH and double SH3 domains 1" Q86WN1 5 141639302-141651418 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 47.7" "Cell type enhanced" "Detected in many" "Retinal horizontal cells: 54.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043795 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 109: Neurons - Neuronal signaling" 1 Nucleoplasm Cytosol "HPA043795: " "unprognostic (5.24e-2)" "unprognostic (1.92e-1)" "unprognostic (1.46e-1)" "unprognostic (8.70e-3)" "unprognostic (1.96e-1)" "unprognostic (1.51e-3)" "unprognostic (2.32e-3)" "unprognostic (1.65e-3)" "unprognostic (9.73e-3)" "unprognostic (1.09e-3)" "unprognostic (6.45e-2)" "unprognostic (6.01e-2)" "unprognostic (3.83e-1)" "unprognostic (1.12e-1)" "unprognostic (1.29e-2)" "unprognostic (4.11e-2)" "unprognostic (1.89e-1)" "unprognostic (3.36e-1)" "unprognostic (1.92e-1)" "unprognostic (7.78e-3)" "unprognostic (6.76e-2)" "unprognostic (7.27e-2)" "potential prognostic unfavorable (3.88e-4)" "unprognostic (5.96e-3)" "unprognostic (7.64e-3)" "potential prognostic favorable (6.95e-4)" "unprognostic (4.87e-2)" "unprognostic (1.17e-1)" "unprognostic (4.70e-1)" "unprognostic (8.47e-2)" "unprognostic (2.00e-1)" FCHSD2 "KIAA0769, SH3MD3" ENSG00000137478 "FCH and double SH3 domains 2" O94868 11 72836745-73142318 "Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 1232.7;Microglia: 1168.0;Neutrophils: 884.3;pDCs: 2334.7" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 1570.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adrenal gland - Fibroblasts, Breast - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038545, HPA038546" Uncertain Approved "Nuclear speckles,Plasma membrane,Actin filaments,Focal adhesion sites" Yes No "Cluster 32: Basophils - Transcription" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 7: Non-specific - Ribosome" "Cluster 55: Lymphoma - Immune response" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 11 "Plasma membrane, Actin filaments" "Nuclear speckles, Focal adhesion sites" "HPA038545: , HPA038546: " "unprognostic (1.76e-3)" "unprognostic (4.06e-1)" "unprognostic (6.82e-2)" "unprognostic (4.10e-2)" "unprognostic (3.97e-1)" "unprognostic (3.36e-1)" "unprognostic (7.84e-2)" "unprognostic (8.27e-3)" "potential prognostic favorable (3.74e-4)" "unprognostic (2.22e-2)" "potential prognostic favorable (3.15e-5)" "unprognostic (4.52e-2)" "unprognostic (8.58e-2)" "unprognostic (3.69e-2)" "unprognostic (1.32e-2)" "unprognostic (2.17e-2)" "unprognostic (5.58e-2)" "unprognostic (5.80e-2)" "unprognostic (3.00e-1)" "unprognostic (7.84e-2)" "unprognostic (6.35e-2)" "unprognostic (3.19e-2)" "unprognostic (6.21e-3)" "unprognostic (8.92e-2)" "unprognostic (2.19e-2)" "unprognostic (1.72e-2)" "unprognostic (5.51e-3)" "unprognostic (5.12e-2)" "unprognostic (1.73e-1)" "unprognostic (5.27e-2)" "unprognostic (2.35e-1)" FCMR "FAIM3, FcmuR, TOSO" ENSG00000162894 "Fc mu receptor" O60667 1 206903317-206923247 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Immunity Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 56.3;lymphoid tissue: 169.0" "Cell type enhanced" "Detected in many" "B-cells: 296.5;Epicardial cells: 91.0;Innate lymphoid cells: 42.3;NK-cells: 108.3;T-cells: 99.7;Thymocytes: 61.8" "Cell type enriched" "Detected in single" 81 "leukocyte: 71.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 10 "Leukemia: 23.9;lymphoma: 55.8;Myeloma: 45.1" "Spleen - B-cells (Spleen)" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA003910 Approved Approved "Nucleoplasm,Golgi apparatus,Plasma membrane,Centrosome" "Secreted to blood" Receptor NA NA 2500000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 1 "Nucleoplasm, Plasma membrane" "Golgi apparatus, Centrosome" "HPA003910: " "unprognostic (4.08e-2)" "unprognostic (3.91e-3)" "unprognostic (7.05e-3)" "unprognostic (6.12e-2)" "unprognostic (2.23e-1)" "unprognostic (3.95e-1)" "unprognostic (2.99e-1)" "unprognostic (1.57e-3)" "unprognostic (3.38e-1)" "potential prognostic favorable (7.92e-4)" "unprognostic (1.38e-1)" "unprognostic (1.03e-2)" "potential prognostic favorable (3.00e-4)" "potential prognostic favorable (8.47e-4)" "unprognostic (1.16e-1)" "unprognostic (1.27e-1)" "unprognostic (2.22e-1)" "unprognostic (1.19e-1)" "unprognostic (1.05e-1)" "potential prognostic favorable (8.26e-4)" "unprognostic (9.73e-2)" "unprognostic (3.18e-1)" "unprognostic (2.50e-1)" "unprognostic (3.09e-2)" "unprognostic (2.55e-3)" "unprognostic (6.59e-2)" "unprognostic (5.53e-2)" "unprognostic (2.90e-2)" "unprognostic (1.14e-1)" FCN1 FCNM ENSG00000085265 "Ficolin 1" O00602 9 134903232-134917912 "Plasma proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "bone marrow: 150.0;lymphoid tissue: 45.0" "Cell type enhanced" "Detected in some" "cDC: 203.9;Macrophages: 82.6;Monocyte progenitors: 322.6;monocytes: 1136.9;Neutrophil progenitors: 713.6;Neutrophils: 345.7" "Cell type enriched" "Detected in single" 606 "leukocyte: 101.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 1694.0;intermediate monocyte: 1189.2" "Lineage enhanced" "Detected in all" "monocytes: 1694.0" "Cancer enriched" "Detected in single" 7 "Leukemia: 1.1" "Adipose visceral - Neutrophils, Lung - Neutrophils_2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA000685, HPA001295, CAB016760" Enhanced "Secreted to blood" Immunity NA NA 1060000000 29000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 15: Bone marrow - Innate immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 13 "CAB016760: , HPA000685: , HPA001295: " "unprognostic (5.76e-2)" "unprognostic (1.62e-2)" "unprognostic (2.27e-1)" "unprognostic (9.34e-2)" "unprognostic (1.42e-1)" "unprognostic (7.87e-2)" "unprognostic (6.55e-2)" "unprognostic (9.51e-2)" "potential prognostic favorable (8.48e-4)" "unprognostic (5.71e-2)" "unprognostic (3.04e-2)" "unprognostic (1.66e-1)" "unprognostic (7.54e-3)" "unprognostic (1.38e-2)" "unprognostic (2.24e-2)" "unprognostic (1.82e-1)" "unprognostic (2.11e-1)" "unprognostic (3.04e-1)" "unprognostic (2.17e-3)" "unprognostic (1.72e-2)" "unprognostic (2.46e-2)" FCN2 "EBP-37, FCNL, ficolin-2, P35" ENSG00000160339 "Ficolin 2" Q15485 9 134880810-134887523 "Plasma proteins, Predicted secreted proteins" "Complement activation lectin pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "adrenal gland: 24.2;liver: 93.1" "Group enriched" "Detected in some" 4 "Breast lactating cells: 50.6;Hepatic stellate cells: 38.7;Kupffer cells: 53.3;Vascular endothelial cells: 42.9" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Liver Hepatocellular Carcinoma (TCGA): 2.8" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "classical monocyte: 5.5;intermediate monocyte: 4.6" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Prostate - Prostate glandular cells" "Region enriched" "Detected in some" 24 "spinal cord: 51.0" "Secreted to blood" Immunity NA NA 8100000000 430000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 53: Liver - Plasma proteins" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 4 "unprognostic (2.45e-1)" "unprognostic (3.78e-2)" "potential prognostic favorable (1.88e-4)" "unprognostic (1.68e-2)" "unprognostic (3.69e-2)" "unprognostic (8.70e-3)" "unprognostic (8.94e-2)" FCN3 "FCNH, HAKA1" ENSG00000142748 "Ficolin 3" O75636 1 27369110-27374824 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement activation lectin pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "liver: 260.7;lung: 688.3" "Cell type enriched" "Detected in some" 4 "Vascular endothelial cells: 388.8" "Cell type enhanced" "Detected in single" "endothelial cell: 2.4" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 41.0" "Region enriched" "Detected in all" 8 "choroid plexus: 20.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Sinusoid Endothelial cells" CAB025945 Approved "Secreted to blood" Immunity NA NA 22800000000 4600000000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 36: Choroid plexus - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 2 "CAB025945: " "unprognostic (2.73e-2)" "unprognostic (9.48e-2)" "unprognostic (2.23e-1)" "unprognostic (2.39e-3)" "unprognostic (4.53e-2)" "unprognostic (6.28e-2)" "potential prognostic unfavorable (2.64e-4)" "unprognostic (5.44e-2)" "unprognostic (1.05e-1)" "unprognostic (2.66e-3)" "validated prognostic favorable (7.23e-6)" "validated prognostic favorable (1.33e-5)" "unprognostic (3.09e-2)" "unprognostic (1.19e-3)" "unprognostic (5.18e-3)" "unprognostic (3.47e-2)" "unprognostic (3.57e-2)" "unprognostic (1.01e-3)" "unprognostic (2.89e-1)" "unprognostic (4.65e-3)" "unprognostic (1.72e-2)" "unprognostic (4.52e-2)" "unprognostic (1.10e-1)" "unprognostic (6.22e-2)" "unprognostic (6.30e-2)" "unprognostic (1.36e-1)" "potential prognostic favorable (9.24e-4)" "unprognostic (2.94e-3)" "unprognostic (1.91e-1)" "unprognostic (3.01e-2)" "unprognostic (2.10e-2)" FCRL1 "CD307a, FCRH1, IFGP1, IRTA5" ENSG00000163534 "Fc receptor like 1" Q96LA6 1 157794403-157820120 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 16 "bone marrow: 7.6;intestine: 7.9;lymphoid tissue: 25.5" "Cell type enriched" "Detected in some" 4 "B-cells: 543.2" "Cell type enriched" "Detected in single" 38 "leukocyte: 24.3" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 49 "memory B-cell: 39.4;naive B-cell: 68.3" "Lineage enriched" "Detected in many" 62 "B-cells: 68.3" "Cancer enriched" "Detected in single" 36 "lymphoma: 9.1" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA013323 Enhanced NA NA 87000 "Cluster 14: Non-specific - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" "HPA013323: " "unprognostic (1.35e-3)" FCRL2 "CD307b, FCRH2, IRTA4, SPAP1" ENSG00000132704 "Fc receptor like 2" Q96LA5 1 157745733-157777132 "CD markers, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "intestine: 19.5;lymphoid tissue: 33.2" "Group enriched" "Detected in some" 14 "B-cells: 141.3;Plasma cells: 55.3" "Cell type enriched" "Detected in single" 36 "leukocyte: 9.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 34 "memory B-cell: 29.8;naive B-cell: 18.5" "Lineage enriched" "Detected in single" 42 "B-cells: 29.8" "Group enriched" "Detected in some" 71 "lymphoma: 13.7;Myeloma: 5.3" "Breast - Plasma cells, Lung - B-cells (Lung), Minor Salivary Gland - Plasma cells, Pituitary gland - Plasma cells, Spleen - B-cells (Spleen)" NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 9: Non-specific - Receptor signaling" "Cluster 55: Lymphoma - Immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 2 "potential prognostic favorable (4.10e-4)" "unprognostic (1.15e-1)" "potential prognostic favorable (6.25e-4)" "unprognostic (2.57e-1)" "unprognostic (2.89e-1)" "unprognostic (2.81e-2)" "unprognostic (2.45e-2)" "unprognostic (3.25e-2)" "unprognostic (2.67e-3)" "unprognostic (2.75e-1)" FCRL3 "CD307c, FCRH3, IFGP3, IRTA3, SPAP2, SPAP2a, SPAP2b, SPAP2c, SPAP2d, SPAP2e" ENSG00000160856 "Fc receptor like 3" Q96P31 1 157674321-157700769 "CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Fertilization Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "lymphoid tissue: 46.2" "Cell type enhanced" "Detected in some" "B-cells: 54.9;Early spermatids: 10.1;Hepatic stellate cells: 6.5;Late primary spermatocytes: 4.8;Late spermatids: 15.5;NK-cells: 47.1;T-cells: 10.3" "Cell type enriched" "Detected in single" 63 "leukocyte: 33.2" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 2.3" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "naive B-cell: 35.4" "Group enriched" "Detected in many" 54 "B-cells: 35.4;NK-cells: 20.5;T-cells: 19.1" "Cancer enriched" "Detected in single" 81 "lymphoma: 17.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Heart muscle - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Pituitary gland - T-cells, Spleen - B-cells (Spleen), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" HPA048022 Enhanced NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 1 "HPA048022: " "unprognostic (3.41e-3)" "unprognostic (1.67e-1)" "unprognostic (2.38e-1)" "unprognostic (1.65e-3)" "unprognostic (2.55e-1)" "unprognostic (1.32e-1)" "unprognostic (8.42e-2)" "unprognostic (4.83e-2)" "unprognostic (2.78e-1)" "unprognostic (1.16e-1)" FCRL4 "CD307d, FCRH4, IGFP2, IRTA1" ENSG00000163518 "Fc receptor like 4" Q96PJ5 1 157573747-157598085 "Cancer-related genes, CD markers, Disease related genes, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 9.8" "Group enriched" "Detected in some" 4 "B-cells: 3.4;Gastric chief cells: 1.1;Goblet cells: 3.2;NK-cells: 3.8;Plasma cells: 1.6;Thymocytes: 3.4" "Cell type enhanced" "Detected in single" "LAMP5-LHX6 and Chandelier: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "lymphoma: 1.7" "Spleen - B-cells (Spleen)" "Not detected" "Not detected" HPA054030 Approved NA NA "Cluster 18: Lymphoid tissue - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 67: Plasma cells - Plasma cell differentiation" 8 "HPA054030: " FCRL5 "BXMAS1, CD307e, FCRH5, IRTA2" ENSG00000143297 "Fc receptor like 5" Q96RD9 1 157513377-157552515 "CD markers, Disease related genes, Predicted membrane proteins, Predicted secreted proteins" Fertilization Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "lymphoid tissue: 34.1" "Cell type enhanced" "Detected in some" "B-cells: 114.5;Early spermatids: 62.1;Late primary spermatocytes: 38.1;Plasma cells: 350.1" "Cell type enriched" "Detected in single" 18 "leukocyte: 6.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "memory B-cell: 13.0;naive B-cell: 14.2" "Lineage enriched" "Detected in single" 17 "B-cells: 14.2" "Group enriched" "Detected in some" 12 "lymphoma: 20.4;Myeloma: 7.2" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Plasma cells" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" Receptor NA NA 169000000 12000000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 44: Plasma cells - Antibody production & secretion" 2 "potential prognostic favorable (4.47e-4)" "unprognostic (5.25e-2)" "unprognostic (6.86e-3)" "unprognostic (5.14e-2)" "unprognostic (1.37e-1)" "potential prognostic favorable (4.64e-5)" "unprognostic (2.59e-1)" "unprognostic (1.80e-2)" "unprognostic (2.44e-3)" "unprognostic (9.65e-2)" "unprognostic (2.17e-1)" "unprognostic (2.55e-1)" "unprognostic (1.94e-1)" "unprognostic (2.46e-2)" "unprognostic (6.90e-2)" "unprognostic (3.86e-1)" FCRL6 "FcRH6, FLJ16056, IFGP6" ENSG00000181036 "Fc receptor like 6" Q6DN72 1 159800511-159816257 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 7.4;lymphoid tissue: 12.0" "Group enriched" "Detected in some" 8 "NK-cells: 81.1;T-cells: 35.6" "Cell type enriched" "Detected in single" 178 "leukocyte: 90.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 143.2;memory CD8 T-cell: 134.3;naive CD8 T-cell: 103.2;NK-cell: 51.5" "Group enriched" "Detected in many" 26 "NK-cells: 51.5;T-cells: 143.2" "Not detected" "Not detected" "Adipose visceral - T-cells, Colon - T-cells, Heart muscle - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 1 "unprognostic (9.97e-2)" "unprognostic (9.84e-2)" "unprognostic (1.87e-2)" "unprognostic (5.64e-2)" "unprognostic (2.58e-3)" "potential prognostic favorable (2.31e-4)" "unprognostic (2.91e-1)" "unprognostic (1.34e-1)" "unprognostic (2.51e-1)" "unprognostic (6.79e-2)" "unprognostic (4.36e-2)" "unprognostic (1.80e-1)" "unprognostic (3.28e-2)" FCRLA "FCRL, FCRLb, FCRLc1, FCRLc2, FCRLd, FCRLe, FCRLM1, FCRLX, FREB, MGC4595" ENSG00000132185 "Fc receptor like A" Q7L513 1 161706972-161714352 "Predicted intracellular proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 92.1" "Cell type enhanced" "Detected in some" "B-cells: 67.8;Melanocytes: 26.9;pDCs: 6.8;Plasma cells: 15.5" "Group enriched" "Detected in some" 6 "committed oligodendrocyte precursor: 2.3;leukocyte: 1.7" "Cancer enriched" "Detected in many" 23 "Skin Cutaneous Melanoma (TCGA): 107.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "memory B-cell: 369.4;naive B-cell: 342.8" "Lineage enriched" "Detected in many" 10 "B-cells: 369.4" "Cancer enriched" "Detected in some" 5 "lymphoma: 220.7" "Minor Salivary Gland - Plasma cells, Skin - Melanocytes, Spleen - B-cells (Spleen)" "Not detected" "Not detected" "Not detected" "Not detected" CAB016545 Enhanced "Intracellular and membrane" Other NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" "CAB016545: " "unprognostic (1.28e-1)" "potential prognostic favorable (5.77e-4)" "unprognostic (1.32e-1)" "unprognostic (3.52e-1)" "unprognostic (4.23e-1)" "unprognostic (2.32e-2)" "potential prognostic favorable (2.93e-4)" "unprognostic (9.99e-2)" "potential prognostic favorable (6.04e-4)" "unprognostic (9.86e-3)" "unprognostic (1.89e-1)" "unprognostic (9.89e-2)" "unprognostic (2.68e-2)" "unprognostic (3.96e-2)" "unprognostic (1.44e-1)" "unprognostic (4.31e-2)" "unprognostic (8.20e-2)" "unprognostic (2.51e-1)" FCRLB "FCRL2, FCRLM2, FCRLY, FLJ31052, FREB-2" ENSG00000162746 "Fc receptor like B" Q6BAA4 1 161721544-161728143 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.6" "Cell type enhanced" "Detected in some" "Extravillous trophoblasts: 7.3;Fallopian secretory cells: 6.0;Granulosa cells: 7.3;Hepatic stellate cells: 6.5;NK-cells: 5.6;Thymic myoid cells: 10.9;Urothelial cells: 8.2" "Cell type enhanced" "Detected in many" "hippocampal CA4: 6.3" "Cancer enhanced" "Detected in some" "Breast Invasive Carcinoma (TCGA): 5.7" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in some" 17 "lymphoma: 25.9" "Not detected" "Not detected" "Not detected" "Not detected" CAB026139 Uncertain Supported Cytosol "Intracellular and membrane" "No annotated function" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" Cytosol "CAB026139: " "unprognostic (8.47e-2)" "unprognostic (3.00e-1)" "unprognostic (7.02e-3)" "unprognostic (3.32e-2)" "unprognostic (3.18e-1)" "unprognostic (1.12e-1)" "unprognostic (2.01e-1)" "unprognostic (3.32e-2)" "unprognostic (2.93e-2)" "unprognostic (1.91e-2)" FCSK "FLJ39408, FUK" ENSG00000157353 "Fucose kinase" Q8N0W3 16 70454595-70480274 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 38.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041971 Approved Approved Vesicles NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 70: Non-specific - Protein processing" "Cluster 25: Non-specific - Transcription" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 3: Early primary spermatocytes - Early meiosis" 2 Vesicles "HPA041971: " "unprognostic (1.01e-1)" "unprognostic (1.81e-1)" "unprognostic (1.43e-2)" "unprognostic (9.07e-2)" "unprognostic (1.24e-1)" "unprognostic (2.06e-2)" "unprognostic (4.33e-2)" "unprognostic (4.23e-3)" "unprognostic (4.80e-3)" "potential prognostic favorable (1.60e-6)" "unprognostic (7.64e-2)" "potential prognostic favorable (2.10e-5)" "unprognostic (1.13e-2)" "unprognostic (3.58e-2)" "unprognostic (1.73e-1)" "unprognostic (1.87e-2)" "unprognostic (1.40e-1)" "unprognostic (1.04e-1)" "unprognostic (6.03e-2)" "unprognostic (1.72e-1)" "unprognostic (1.80e-1)" "unprognostic (4.85e-2)" "unprognostic (2.57e-2)" "unprognostic (3.48e-2)" "unprognostic (2.99e-1)" "unprognostic (3.50e-2)" "unprognostic (1.75e-1)" "unprognostic (2.40e-1)" "unprognostic (2.11e-1)" FDCSP "C4orf7, FDC-SP" ENSG00000181617 "Follicular dendritic cell secreted protein" Q8NFU4 4 70226124-70235252 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 31 "lymphoid tissue: 3043.3;salivary gland: 7470.4" "Cell type enriched" "Detected in some" 4 "Salivary acinar cells: 12134.7" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Breast Invasive Carcinoma (TCGA): 534.7;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 404.0;Head and Neck Squamous Cell Carcinoma (TCGA): 739.9;Lung Squamous Cell Carcinoma (TCGA): 420.8" "Region enhanced" "Detected in single" "midbrain: 1.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 85.9;Rhabdoid: 24.2" "Minor Salivary Gland - Minor salivary glandular cells" "Not detected" "Not detected" "HPA014326, CAB014890" Enhanced "Secreted in other tissues" "No annotated function" NA NA "Cluster 82: Salivary gland - Secretion" "Cluster 3: Choroid plexus - Cilium" "Cluster 1: Neuronal - Visual perception" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 1 "CAB014890: , HPA014326: " "unprognostic (2.09e-1)" "unprognostic (3.31e-3)" "unprognostic (8.78e-2)" "unprognostic (1.76e-1)" "unprognostic (6.56e-2)" "unprognostic (2.38e-1)" "potential prognostic favorable (2.66e-4)" "potential prognostic unfavorable (1.52e-5)" "unprognostic (6.24e-2)" "potential prognostic unfavorable (3.35e-5)" "unprognostic (6.08e-3)" "unprognostic (2.50e-3)" "unprognostic (9.53e-3)" "unprognostic (8.30e-3)" "unprognostic (7.75e-2)" "unprognostic (2.74e-1)" "unprognostic (1.31e-1)" "unprognostic (1.06e-1)" "unprognostic (2.15e-1)" "unprognostic (4.89e-1)" "unprognostic (7.80e-2)" "unprognostic (1.96e-1)" "unprognostic (1.83e-1)" "unprognostic (1.93e-1)" "unprognostic (4.53e-2)" "unprognostic (2.47e-1)" "unprognostic (8.36e-3)" FDFT1 SQS ENSG00000079459 "Farnesyl-diphosphate farnesyltransferase 1" P37268 8 11795573-11839304 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 158.2;Late primary spermatocytes: 236.1;Late spermatids: 165.2;Oligodendrocytes: 137.3;Oocytes: 152.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008874 Approved Supported "Endoplasmic reticulum" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 102: Non-specific - Mixed function" 34 "Endoplasmic reticulum" "HPA008874: " "unprognostic (2.69e-1)" "unprognostic (1.18e-2)" "unprognostic (1.11e-1)" "unprognostic (4.24e-2)" "potential prognostic favorable (7.44e-4)" "unprognostic (1.52e-1)" "unprognostic (1.25e-1)" "unprognostic (2.13e-3)" "unprognostic (3.23e-1)" "unprognostic (4.19e-3)" "validated prognostic favorable (1.64e-8)" "validated prognostic favorable (4.59e-4)" "unprognostic (1.12e-1)" "validated prognostic unfavorable (2.46e-4)" "validated prognostic unfavorable (4.87e-4)" "unprognostic (2.25e-1)" "unprognostic (1.02e-1)" "unprognostic (1.69e-1)" "unprognostic (1.03e-3)" "unprognostic (2.52e-1)" "unprognostic (1.05e-2)" "unprognostic (1.13e-3)" "unprognostic (1.33e-1)" "unprognostic (8.59e-2)" "unprognostic (1.07e-2)" "unprognostic (1.80e-1)" "unprognostic (1.50e-1)" "unprognostic (3.74e-2)" "unprognostic (1.52e-1)" "unprognostic (2.91e-1)" "unprognostic (1.05e-2)" FDPS ENSG00000160752 "Farnesyl diphosphate synthase" P14324 1 155308748-155320666 "Disease related genes, Enzymes, Essential proteins, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Host-virus interaction, Isoprene biosynthesis, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Transferase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 332.6" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 465.5;Breast lactating cells: 497.3;Colonocytes: 712.8;Epididymal principal cells: 806.1;Esophageal apical cells: 653.7;Esophageal suprabasal cells: 535.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Colon - Macrophages, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028200 Approved Approved Nucleoplasm,Cytosol NA NA 3900000 "Cluster 25: Non-specific - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 22 Cytosol Nucleoplasm "HPA028200: " "unprognostic (3.56e-2)" "unprognostic (1.95e-1)" "unprognostic (2.29e-2)" "unprognostic (2.27e-2)" "unprognostic (1.13e-1)" "unprognostic (1.68e-1)" "unprognostic (4.76e-2)" "unprognostic (8.31e-3)" "unprognostic (2.24e-2)" "unprognostic (6.62e-2)" "potential prognostic favorable (2.24e-6)" "unprognostic (3.22e-3)" "unprognostic (1.94e-1)" "unprognostic (1.47e-3)" "unprognostic (1.35e-3)" "unprognostic (1.41e-2)" "unprognostic (2.18e-2)" "unprognostic (1.98e-1)" "unprognostic (1.87e-1)" "unprognostic (1.81e-2)" "unprognostic (2.16e-1)" "unprognostic (6.36e-2)" "unprognostic (3.88e-1)" "unprognostic (6.98e-2)" "unprognostic (1.14e-1)" "unprognostic (1.77e-1)" "unprognostic (4.45e-2)" "unprognostic (4.03e-1)" "unprognostic (2.11e-1)" "unprognostic (4.39e-1)" "unprognostic (2.96e-2)" FDX1 "ADX, FDX" ENSG00000137714 "Ferredoxin 1" P10109 11 110429948-110464884 "Predicted intracellular proteins" "Cholesterol metabolism, Electron transport, Lipid metabolism, Steroid metabolism, Steroidogenesis, Sterol metabolism, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "adrenal gland: 300.4" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 1824.0;Mast cells: 405.8;Syncytiotrophoblasts: 1367.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041630, HPA062087" Enhanced Enhanced Mitochondria NA NA 6100 "Cluster 3: Non-specific - Nuclear processes" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 18: Adrenal cortex cells - Steroidogensis" 1 Mitochondria "HPA041630: , HPA062087: " "unprognostic (3.73e-1)" "unprognostic (9.50e-2)" "unprognostic (3.36e-2)" "unprognostic (4.30e-2)" "unprognostic (1.27e-2)" "unprognostic (1.95e-1)" "unprognostic (2.80e-1)" "unprognostic (2.79e-1)" "unprognostic (3.50e-3)" "unprognostic (1.14e-1)" "potential prognostic favorable (4.74e-8)" "unprognostic (2.56e-3)" "unprognostic (1.41e-2)" "unprognostic (1.03e-2)" "potential prognostic favorable (1.64e-5)" "unprognostic (8.33e-2)" "unprognostic (1.30e-1)" "unprognostic (4.81e-2)" "unprognostic (4.85e-2)" "unprognostic (1.43e-1)" "unprognostic (8.80e-2)" "unprognostic (7.55e-2)" "unprognostic (3.28e-1)" "unprognostic (1.72e-1)" "unprognostic (3.59e-2)" "unprognostic (2.54e-1)" "potential prognostic unfavorable (8.41e-4)" "unprognostic (1.64e-1)" "unprognostic (1.54e-1)" "unprognostic (8.04e-2)" "unprognostic (4.44e-2)" FDX2 "FDX1L, MGC19604" ENSG00000267673 "Ferredoxin 2" Q6P4F2 19 10309916-10316015 "Disease related genes, Essential proteins, Predicted intracellular proteins" "Electron transport, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043986 Approved NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 14: Neurons - Synaptic function" "Cluster 23: Non-specific - Transcription" "Cluster 98: Neurons - Neurotransmission & signaling" 2 "HPA043986: " "unprognostic (2.64e-1)" "unprognostic (2.84e-1)" "unprognostic (6.86e-2)" "unprognostic (2.64e-1)" "unprognostic (6.68e-2)" "unprognostic (4.68e-2)" "unprognostic (3.87e-1)" "unprognostic (5.52e-2)" "unprognostic (1.67e-3)" "unprognostic (1.25e-1)" "unprognostic (3.07e-2)" "unprognostic (4.76e-3)" "potential prognostic unfavorable (3.96e-4)" "unprognostic (3.40e-1)" "unprognostic (1.45e-2)" "unprognostic (5.75e-2)" "unprognostic (1.01e-1)" "unprognostic (2.90e-2)" "unprognostic (1.34e-1)" "unprognostic (1.41e-2)" "unprognostic (5.58e-2)" "unprognostic (6.85e-3)" "unprognostic (1.59e-1)" "unprognostic (6.94e-2)" "unprognostic (8.42e-2)" "unprognostic (1.85e-1)" "unprognostic (2.36e-1)" "unprognostic (3.50e-1)" "unprognostic (3.31e-1)" FDXACB1 "hCG_2033039, LOC91893" ENSG00000255561 "Ferredoxin-fold anticodon binding domain containing 1" Q9BRP7 11 111874056-111881243 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 13.1;Epicardial cells: 4.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039012, HPA061375" Uncertain Uncertain Nucleoplasm,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 24: Non-specific - Unknown function" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 3 "Nucleoplasm, Cytosol" "HPA039012: , HPA061375: " "unprognostic (1.12e-1)" "unprognostic (5.17e-2)" "unprognostic (2.71e-1)" "unprognostic (1.08e-1)" "unprognostic (5.28e-2)" "unprognostic (6.85e-3)" "unprognostic (1.66e-2)" "unprognostic (7.27e-2)" "unprognostic (1.69e-1)" "unprognostic (1.22e-1)" "unprognostic (1.57e-1)" "unprognostic (9.47e-2)" "unprognostic (5.99e-2)" "unprognostic (1.75e-1)" "unprognostic (1.38e-1)" "unprognostic (4.24e-2)" "unprognostic (1.91e-1)" "unprognostic (3.88e-2)" "unprognostic (1.29e-2)" "unprognostic (9.67e-2)" "unprognostic (5.26e-2)" "unprognostic (3.51e-2)" "unprognostic (1.45e-1)" "unprognostic (1.47e-1)" "unprognostic (8.66e-3)" "unprognostic (8.07e-2)" "potential prognostic unfavorable (1.17e-4)" "unprognostic (5.74e-2)" "unprognostic (2.32e-1)" "unprognostic (1.43e-1)" "unprognostic (1.06e-2)" FDXR "ADR, ADXR" ENSG00000161513 "Ferredoxin reductase" P22570 17 74862497-74873031 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Electron transport, Lipid metabolism, Steroid metabolism, Sterol metabolism, Transport" Oxidoreductase "Deafness, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "adrenal gland: 339.7" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 90.5;Cytotrophoblasts: 65.0;Esophageal basal cells: 82.7;Esophageal suprabasal cells: 90.6;Fallopian tube ciliated cells: 95.3;Granulosa cells: 207.6;Respiratory ciliated cells: 83.7;Sertoli cells: 70.7" "Cell type enhanced" "Detected in all" "ependymal cell: 24.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "CAB008597, CAB009818, HPA044393, HPA053673" Enhanced Enhanced Mitochondria NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 40: Non-specific - Unknown function" "Cluster 18: Adrenal cortex cells - Steroidogensis" 1 Mitochondria "CAB008597: , CAB009818: , HPA044393: , HPA053673: " "unprognostic (1.10e-1)" "unprognostic (2.84e-1)" "unprognostic (2.19e-1)" "unprognostic (5.26e-2)" "unprognostic (3.63e-3)" "unprognostic (3.48e-2)" "unprognostic (6.42e-2)" "unprognostic (4.65e-2)" "unprognostic (3.61e-2)" "unprognostic (1.15e-1)" "unprognostic (2.10e-3)" "unprognostic (5.67e-3)" "unprognostic (4.19e-3)" "unprognostic (1.58e-1)" "unprognostic (9.88e-2)" "unprognostic (3.48e-1)" "unprognostic (6.17e-2)" "unprognostic (1.47e-1)" "unprognostic (2.58e-2)" "unprognostic (2.69e-1)" "unprognostic (9.67e-2)" "unprognostic (1.27e-1)" "unprognostic (2.59e-1)" "unprognostic (2.36e-1)" "unprognostic (1.45e-1)" "unprognostic (1.20e-1)" "unprognostic (3.51e-1)" "unprognostic (3.69e-2)" "unprognostic (1.83e-1)" "unprognostic (4.70e-2)" "unprognostic (1.08e-1)" FECH ENSG00000066926 Ferrochelatase P22830 18 57544377-57586732 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Heme biosynthesis, Porphyrin biosynthesis" Lyase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 36.8" "Group enriched" "Detected in many" 4 "Erythrocyte progenitors: 240.8;Erythrocytes: 235.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044100, HPA048177" Approved NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 22 "HPA044100: , HPA048177: " "unprognostic (2.18e-1)" "unprognostic (2.53e-1)" "unprognostic (2.74e-1)" "unprognostic (3.58e-3)" "unprognostic (1.13e-1)" "unprognostic (2.53e-1)" "unprognostic (9.14e-2)" "unprognostic (1.44e-1)" "unprognostic (2.80e-2)" "unprognostic (1.30e-1)" "validated prognostic favorable (4.69e-5)" "validated prognostic favorable (4.76e-4)" "unprognostic (5.78e-3)" "unprognostic (1.05e-1)" "unprognostic (4.81e-2)" "unprognostic (2.67e-3)" "unprognostic (3.52e-2)" "unprognostic (3.98e-3)" "unprognostic (2.01e-1)" "unprognostic (2.01e-1)" "unprognostic (2.43e-2)" "unprognostic (5.72e-2)" "unprognostic (2.90e-2)" "unprognostic (1.24e-2)" "unprognostic (1.32e-1)" "unprognostic (5.87e-2)" "unprognostic (1.79e-2)" "unprognostic (7.72e-2)" "unprognostic (1.48e-1)" "unprognostic (3.01e-2)" "unprognostic (4.49e-1)" FEM1A ENSG00000141965 "Fem-1 homolog A" Q9BSK4 19 4791734-4801273 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "skeletal muscle: 256.2;tongue: 113.3" "Cell type enhanced" "Detected in many" "Thymic myoid cells: 130.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016565, HPA063622" Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 15: Non-specific - Transcription" "Cluster 23: Non-specific - Transcription" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 31 "Nucleoplasm, Golgi apparatus" Cytosol "HPA016565: , HPA063622: " "unprognostic (2.91e-3)" "unprognostic (1.03e-1)" "unprognostic (4.14e-1)" "unprognostic (4.87e-2)" "unprognostic (9.94e-2)" "unprognostic (1.52e-1)" "unprognostic (1.50e-1)" "unprognostic (1.68e-2)" "unprognostic (5.94e-2)" "unprognostic (1.53e-1)" "potential prognostic favorable (9.72e-7)" "unprognostic (3.92e-3)" "unprognostic (1.04e-2)" "unprognostic (3.51e-1)" "unprognostic (4.59e-2)" "unprognostic (5.53e-2)" "unprognostic (3.71e-2)" "unprognostic (3.01e-2)" "unprognostic (1.26e-3)" "unprognostic (4.09e-1)" "potential prognostic unfavorable (2.75e-4)" "unprognostic (4.26e-2)" "unprognostic (7.39e-2)" "unprognostic (9.90e-2)" "unprognostic (1.08e-1)" "unprognostic (2.18e-1)" "unprognostic (2.30e-1)" "potential prognostic favorable (6.69e-4)" "unprognostic (1.64e-1)" "unprognostic (1.26e-1)" "unprognostic (6.70e-3)" FEM1B ENSG00000169018 "Fem-1 homolog B" Q9UK73 15 68277745-68295862 "Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 899.5;Late primary spermatocytes: 377.8;Late spermatids: 364.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041920, HPA042192" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 39: Testis - Nuclear processes" "Cluster 34: Non-specific - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 28 Nucleoplasm Cytosol "HPA041920: , HPA042192: " "unprognostic (1.81e-1)" "unprognostic (6.44e-2)" "unprognostic (1.19e-1)" "unprognostic (3.64e-2)" "unprognostic (1.17e-1)" "unprognostic (1.95e-1)" "unprognostic (2.55e-2)" "unprognostic (1.13e-2)" "unprognostic (5.23e-2)" "unprognostic (6.56e-3)" "validated prognostic favorable (8.73e-8)" "validated prognostic favorable (4.69e-4)" "unprognostic (6.97e-2)" "unprognostic (1.20e-1)" "unprognostic (2.85e-1)" "unprognostic (2.06e-1)" "unprognostic (1.28e-2)" "unprognostic (2.68e-1)" "unprognostic (1.08e-1)" "unprognostic (3.46e-2)" "unprognostic (8.01e-2)" "unprognostic (1.28e-1)" "unprognostic (3.71e-2)" "unprognostic (8.83e-2)" "unprognostic (2.72e-2)" "unprognostic (1.33e-2)" "unprognostic (1.89e-1)" "unprognostic (2.57e-2)" "unprognostic (1.44e-1)" "unprognostic (2.74e-2)" "unprognostic (9.30e-2)" FEM1C "EUROIMAGE686608, EUROIMAGE783647, FEM1A, KIAA1785" ENSG00000145780 "Fem-1 homolog C" Q96JP0 5 115520908-115544775 "Disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 59.6" "Cell type enhanced" "Detected in many" "Late spermatids: 146.7;Neutrophil progenitors: 122.2;Neutrophils: 149.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059919, HPA060977" Approved Enhanced Nucleoplasm NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 16: Non-specific - Transcription" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 8 Nucleoplasm "HPA059919: , HPA060977: " "unprognostic (1.22e-2)" "unprognostic (1.79e-3)" "unprognostic (8.47e-2)" "unprognostic (1.33e-1)" "unprognostic (2.13e-1)" "unprognostic (9.95e-3)" "unprognostic (1.65e-1)" "unprognostic (4.12e-3)" "unprognostic (2.38e-1)" "unprognostic (2.26e-3)" "unprognostic (3.06e-3)" "unprognostic (3.20e-3)" "unprognostic (1.44e-1)" "unprognostic (2.83e-1)" "unprognostic (6.11e-2)" "unprognostic (1.93e-1)" "unprognostic (1.22e-1)" "unprognostic (2.20e-1)" "unprognostic (2.46e-2)" "unprognostic (3.90e-2)" "unprognostic (7.75e-3)" "unprognostic (1.27e-3)" "unprognostic (1.32e-2)" "unprognostic (1.60e-1)" "unprognostic (2.81e-3)" "unprognostic (4.74e-2)" "unprognostic (1.45e-1)" "unprognostic (1.94e-1)" "unprognostic (3.24e-1)" "unprognostic (9.48e-3)" "unprognostic (2.08e-1)" FEN1 "FEN-1, MF1, RAD2" ENSG00000168496 "Flap structure-specific endonuclease 1" P39748 11 61792911-61797238 "Cancer-related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication" "Endonuclease, Exonuclease, Hydrolase, Nuclease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 42.9" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 1.2;Early primary spermatocytes: 3.8;Early spermatids: 1.3;Erythrocyte progenitors: 3.5;Late primary spermatocytes: 1.8;Megakaryocyte progenitors: 1.5;Monocyte progenitors: 1.1;Oocytes: 4.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002262, HPA006748, HPA073857" Enhanced Supported Nucleoplasm,Nucleoli NA Yes 110000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 24: Non-specific - Unknown function" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 35 Nucleoplasm Nucleoli "CAB002262: , HPA006748: , HPA073857: " "unprognostic (2.00e-2)" "unprognostic (7.16e-2)" "unprognostic (1.16e-1)" "unprognostic (1.43e-1)" "unprognostic (1.22e-1)" "unprognostic (3.07e-1)" "unprognostic (3.05e-1)" "unprognostic (4.96e-2)" "unprognostic (2.19e-1)" "unprognostic (7.26e-3)" "unprognostic (1.79e-3)" "unprognostic (6.57e-2)" "potential prognostic unfavorable (5.52e-5)" "validated prognostic unfavorable (1.03e-6)" "validated prognostic unfavorable (3.71e-8)" "validated prognostic unfavorable (3.81e-5)" "validated prognostic unfavorable (1.02e-5)" "unprognostic (2.05e-2)" "unprognostic (4.43e-2)" "unprognostic (1.74e-2)" "unprognostic (4.93e-1)" "potential prognostic unfavorable (6.44e-4)" "unprognostic (6.98e-2)" "unprognostic (1.99e-2)" "unprognostic (9.60e-2)" "unprognostic (3.40e-2)" "unprognostic (4.01e-1)" "unprognostic (2.70e-3)" "unprognostic (4.11e-1)" "unprognostic (3.39e-2)" "unprognostic (1.87e-1)" FER "PPP1R74, TYK3" ENSG00000151422 "FER tyrosine kinase" P16591 5 108747841-109196841 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Mast cells: 2092.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007641, CAB022464" Approved Supported Cytosol NA NA "Cluster 61: Non-specific - Transcription" "Cluster 22: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 58: Mast cells - Allergic inflammatory responses" 13 Cytosol "CAB022464: , HPA007641: " "unprognostic (1.05e-1)" "unprognostic (2.87e-1)" "unprognostic (3.41e-1)" "unprognostic (8.40e-3)" "unprognostic (2.19e-1)" "unprognostic (1.75e-1)" "unprognostic (2.63e-2)" "unprognostic (1.93e-2)" "unprognostic (1.51e-1)" "unprognostic (7.37e-3)" "potential prognostic favorable (5.39e-5)" "unprognostic (1.40e-3)" "unprognostic (2.12e-1)" "unprognostic (1.84e-2)" "unprognostic (1.54e-2)" "unprognostic (3.10e-2)" "unprognostic (3.21e-2)" "unprognostic (2.85e-2)" "unprognostic (1.75e-1)" "unprognostic (4.73e-2)" "unprognostic (4.30e-2)" "unprognostic (3.20e-2)" "potential prognostic unfavorable (2.39e-4)" "unprognostic (2.49e-1)" "unprognostic (1.60e-1)" "unprognostic (4.63e-2)" "unprognostic (2.22e-1)" "unprognostic (2.60e-2)" "unprognostic (1.69e-1)" "unprognostic (3.39e-2)" "unprognostic (1.33e-1)" FER1L5 DKFZp434I0121 ENSG00000249715 "Fer-1 like family member 5" A0AVI2 2 96642737-96704887 "Essential proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 4.0" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 28.1;Early spermatids: 102.6;Ependymal cells: 27.0;Late primary spermatocytes: 62.3;Pituicytes/FSCs: 32.8;Renal collecting duct principal cells: 20.0;Renal connecting tubule cells: 19.4;Respiratory ciliated cells: 18.7" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Breast glandular cells, Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Skin - Outer root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA049568 Approved "Plasma membrane" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" "Plasma membrane" "HPA049568: " FER1L6 C8ORFK23 ENSG00000214814 "Fer-1 like family member 6" Q2WGJ9 8 123851987-124120061 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "stomach 1: 40.7" "Group enriched" "Detected in many" 6 "Foveolar cells: 1012.8;Goblet cells: 1164.9" "Cell type enriched" "Detected in many" 5 "deep-layer near-projecting: 38.6" "Cancer enhanced" "Detected in some" "Pancreatic Adenocarcinoma (TCGA): 5.9;Stomach Adenocarcinoma (TCGA): 7.7" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 1.5;pancreatic cancer: 2.0" "Colon - Colon enterocytes, Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA054117 Enhanced Approved "Plasma membrane,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes NA "Cluster 17: Intestine - Digestion" "Cluster 51: Neurons - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 70: Intestinal goblet cells - Mucin production" "Plasma membrane" "Cytokinetic bridge, Mitotic spindle, Cytosol" "HPA054117: " "unprognostic (3.25e-3)" "unprognostic (6.26e-2)" "unprognostic (1.42e-1)" "unprognostic (2.09e-2)" "unprognostic (6.92e-2)" "unprognostic (2.57e-1)" "unprognostic (1.60e-2)" "unprognostic (1.70e-2)" "unprognostic (4.78e-3)" "unprognostic (2.14e-2)" "unprognostic (6.31e-2)" FERD3L "bHLHa31, N-TWIST, NATO3" ENSG00000146618 "Fer3 like bHLH transcription factor" Q96RJ6 7 19144782-19145421 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in many" "midbrain: 12.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "Neuroblastoma: 6.2" "Not detected" "Not detected" "Region enriched" "Detected in some" 17 "midbrain: 27.0" HPA043494 Uncertain NA NA "Cluster 24: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 7 "HPA043494: " FERMT1 "C20orf42, FLJ20116, KIND1, UNC112A, URP1" ENSG00000101311 "FERM domain containing kindlin 1" Q9BQL6 20 6074845-6123214 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell adhesion" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 29.9" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 125.1;Enteric stem cells: 117.2;Epicardial cells: 789.1;Esophageal apical cells: 248.4;Esophageal basal cells: 133.7;Esophageal suprabasal cells: 188.5;Gastric progenitor cells: 110.2;Oligodendrocyte progenitor cells: 356.2" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 139.2;oligodendrocyte precursor cell: 456.5" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 63.9;Rectum Adenocarcinoma (TCGA): 66.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Breast - Breast myoepithelial cells, Minor Salivary Gland - Minor salivary gland basal cells, Skeletal muscle - Fibroblasts, Skin - Keratinocyte (other), Spleen - Fibroblasts_1, Thyroid gland - Thyroid glandular cells" "Region enriched" "Detected in single" 5 "hippocampal formation: 2.0" "Not detected" "Not detected" "HPA039778, HPA041966" Approved NA NA "Cluster 77: Intestine - Digestion" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" "HPA039778: , HPA041966: " "unprognostic (2.27e-1)" "unprognostic (2.79e-3)" "unprognostic (3.14e-1)" "unprognostic (6.61e-3)" "unprognostic (1.60e-1)" "unprognostic (9.44e-2)" "unprognostic (9.94e-3)" "potential prognostic favorable (3.92e-5)" "unprognostic (1.70e-1)" "unprognostic (4.84e-2)" "unprognostic (8.08e-2)" "potential prognostic unfavorable (8.48e-4)" "unprognostic (3.25e-2)" "unprognostic (1.08e-1)" "unprognostic (1.04e-2)" "unprognostic (3.60e-2)" "unprognostic (4.92e-2)" "unprognostic (7.62e-2)" "potential prognostic unfavorable (1.16e-5)" "unprognostic (1.53e-1)" "unprognostic (1.07e-1)" "unprognostic (6.88e-3)" "potential prognostic favorable (6.69e-4)" "unprognostic (2.20e-3)" "unprognostic (8.21e-2)" "unprognostic (3.18e-1)" FERMT2 "KIND2, mig-2, PLEKHC1, UNC112B" ENSG00000073712 "FERM domain containing kindlin 2" Q96AC1 14 52857268-52952435 "Predicted intracellular proteins" "Cell adhesion, Cell shape, Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 419.6;Podocytes: 360.0;Smooth muscle cells: 536.9" "Cell type enhanced" "Detected in all" "pericyte: 324.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040505, HPA072965" Uncertain Supported "Nucleoplasm,Focal adhesion sites,Cytosol" NA NA 81000 "Cluster 1: T-cells - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 19 "Focal adhesion sites" "Nucleoplasm, Cytosol" "HPA040505: , HPA072965: " "unprognostic (1.29e-1)" "unprognostic (2.93e-2)" "unprognostic (2.46e-1)" "unprognostic (1.72e-1)" "unprognostic (1.18e-2)" "unprognostic (6.62e-2)" "unprognostic (2.91e-2)" "unprognostic (2.50e-2)" "unprognostic (6.94e-3)" "unprognostic (2.65e-2)" "potential prognostic favorable (1.23e-5)" "unprognostic (1.94e-2)" "unprognostic (4.47e-2)" "unprognostic (7.13e-2)" "unprognostic (7.24e-2)" "unprognostic (5.23e-2)" "unprognostic (2.68e-2)" "unprognostic (8.90e-2)" "unprognostic (1.53e-1)" "unprognostic (1.65e-2)" "unprognostic (7.09e-3)" "unprognostic (2.08e-1)" "unprognostic (1.52e-1)" "unprognostic (2.13e-1)" "unprognostic (2.31e-2)" "unprognostic (2.66e-2)" "unprognostic (4.23e-2)" "unprognostic (3.60e-3)" "unprognostic (1.52e-1)" "unprognostic (8.86e-2)" "unprognostic (2.13e-2)" FERMT3 "KIND3, MGC10966, MIG2B, UNC112C, URP2" ENSG00000149781 "FERM domain containing kindlin 3" Q86UX7 11 64205926-64223896 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 95.6;lymphoid tissue: 125.3" "Group enriched" "Detected in many" 6 "Megakaryocytes: 2225.4;Platelets: 2366.1" "Group enriched" "Detected in many" 5 "central nervous system macrophage: 28.9;leukocyte: 49.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 126.8;lymphoma: 93.3;Myeloma: 55.6" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Pituitary gland - Macrophages, Skeletal muscle - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA065231 Approved Vesicles NA NA 200000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 35: RS4;11 - Unknown function" "Cluster 47: Platelets - Hemostasis" 1 Vesicles "HPA065231: " "unprognostic (1.58e-2)" "unprognostic (8.96e-3)" "unprognostic (1.47e-2)" "potential prognostic favorable (7.89e-4)" "unprognostic (3.41e-2)" "unprognostic (1.02e-1)" "unprognostic (1.18e-2)" "unprognostic (1.51e-1)" "unprognostic (1.38e-2)" "unprognostic (3.49e-1)" "unprognostic (2.83e-3)" "unprognostic (3.44e-1)" "unprognostic (1.47e-1)" "unprognostic (2.57e-2)" "unprognostic (1.49e-1)" "unprognostic (1.17e-1)" "unprognostic (1.51e-1)" "unprognostic (9.66e-2)" "unprognostic (2.74e-1)" "unprognostic (4.17e-1)" "unprognostic (1.57e-2)" "unprognostic (2.31e-1)" "unprognostic (1.67e-3)" "unprognostic (3.19e-1)" "unprognostic (2.46e-1)" "unprognostic (1.54e-1)" "unprognostic (5.05e-2)" "unprognostic (9.70e-3)" "unprognostic (3.13e-2)" "unprognostic (1.15e-1)" "unprognostic (3.61e-2)" FES FPS ENSG00000182511 "FES proto-oncogene, tyrosine kinase" P07332 15 90883695-90895776 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 78.7;lymphoid tissue: 110.0" "Cell type enhanced" "Detected in many" "cDC: 57.7;Hofbauer cells: 83.8;Innate lymphoid cells: 65.5;Kupffer cells: 102.5;Macrophages: 49.4;Monocyte progenitors: 80.4;monocytes: 97.3;Neutrophil progenitors: 119.8;Neutrophils: 127.9;Salivary acinar cells: 59.4;Tuft cells: 103.8" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 19.5;endothelial cell: 30.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 316.6" "Group enriched" "Detected in many" 4 "dendritic cells: 162.8;granulocytes: 316.6;monocytes: 151.9" "Cancer enriched" "Detected in many" 5 "Leukemia: 52.5" "Colon - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001376 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 11 "Nucleoplasm, Cytosol" Vesicles "HPA001376: " "unprognostic (6.01e-3)" "unprognostic (1.45e-2)" "unprognostic (2.34e-1)" "unprognostic (4.36e-2)" "potential prognostic unfavorable (9.69e-4)" "unprognostic (1.71e-2)" "potential prognostic unfavorable (8.27e-4)" "unprognostic (1.36e-2)" "unprognostic (4.30e-2)" "unprognostic (2.55e-1)" "unprognostic (2.27e-2)" "unprognostic (1.41e-2)" "unprognostic (3.69e-1)" "unprognostic (1.85e-1)" "unprognostic (4.12e-2)" "unprognostic (6.41e-2)" "unprognostic (2.03e-3)" "unprognostic (9.96e-3)" "unprognostic (1.01e-1)" "unprognostic (7.18e-2)" "unprognostic (9.18e-3)" "unprognostic (1.27e-2)" "unprognostic (6.49e-2)" "unprognostic (8.69e-3)" "unprognostic (2.69e-2)" "potential prognostic favorable (5.94e-5)" "potential prognostic unfavorable (4.54e-4)" "unprognostic (5.01e-3)" "unprognostic (8.12e-2)" "unprognostic (1.20e-1)" "unprognostic (1.84e-1)" FETUB ENSG00000090512 "Fetuin B" Q9UGM5 3 186635969-186653141 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Fertilization "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 27 "liver: 219.3" "Group enriched" "Detected in some" 6 "Esophageal apical cells: 70.4;Hepatocytes: 55.6" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Liver Hepatocellular Carcinoma (TCGA): 44.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Ascending Loop of Henle cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035132, HPA035133" Supported Approved Vesicles "Secreted to blood" "Enzyme inhibitor" NA NA 47500000000 2500000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 6 Vesicles "HPA035132: , HPA035133: " "unprognostic (1.21e-2)" "unprognostic (2.01e-1)" "unprognostic (1.79e-2)" "unprognostic (6.27e-3)" "unprognostic (5.14e-3)" "unprognostic (2.15e-1)" FEV Pet-1 ENSG00000163497 "FEV transcription factor, ETS family member" Q99581 2 218981087-218985184 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 4.0;pituitary gland: 3.3;prostate: 3.0;stomach 1: 3.0" "Cell type enriched" "Detected in some" 7 "Neuroendocrine cells: 565.8" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "Pancreatic Adenocarcinoma (TCGA): 6.4;Prostate Adenocarcinoma (TCGA): 16.6;Stomach Adenocarcinoma (TCGA): 5.0" "Group enriched" "Detected in many" 7 "midbrain: 153.7;pons: 42.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 16 "Neuroblastoma: 40.7" "Adrenal gland - Adrenal medulla cells, Pancreas - Alpha cells, Pituitary gland - Corticotropes, Prostate - Prostate glandular cells, Stomach - Gastric enteroendocrine cells" "Region enhanced" "Detected in single" "midbrain: 1.9" "Group enriched" "Detected in some" 5 "midbrain: 8.3;pons: 4.4" HPA067679 Supported Supported "Nuclear speckles" NA NA "Cluster 77: Intestine - Digestion" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" "Nuclear speckles" "HPA067679: " "unprognostic (2.59e-1)" "unprognostic (1.46e-3)" "unprognostic (3.01e-1)" "unprognostic (1.48e-1)" FEZ1 UNC-76 ENSG00000149557 "Fasciculation and elongation protein zeta 1" Q99689 11 125442881-125592568 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "brain: 281.1" "Cell type enhanced" "Detected in many" "Hofbauer cells: 209.6;Melanocytes: 139.6;Oligodendrocytes: 349.9;Retinal amacrine cells: 108.5;Retinal horizontal cells: 154.3;Schwann cells: 100.2" "Cell type enhanced" "Detected in all" "oligodendrocyte: 520.7" "Cancer enriched" "Detected in many" 8 "Glioblastoma Multiforme (TCGA): 96.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 23.4;MAIT T-cell: 15.6" "Lineage enriched" "Detected in many" 23 "T-cells: 23.4" "Cancer enhanced" "Detected in many" "testis cancer: 25.1" "Adipose visceral - Adipose progenitor cells, Adrenal gland - Fibroblasts, Liver - Sinusoid Endothelial cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038490, HPA076844" Approved Approved Microtubules,Cytosol NA NA "Cluster 1: T-cells - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 80: Oligodendrocytes - Myelination" 31 "Microtubules, Cytosol" "HPA038490: , HPA076844: " "unprognostic (5.04e-2)" "unprognostic (1.37e-1)" "unprognostic (4.86e-3)" "unprognostic (1.54e-3)" "unprognostic (2.81e-1)" "unprognostic (1.11e-1)" "unprognostic (1.93e-1)" "unprognostic (3.96e-1)" "unprognostic (4.74e-3)" "unprognostic (3.47e-3)" "potential prognostic favorable (3.56e-4)" "unprognostic (1.78e-1)" "unprognostic (8.85e-2)" "unprognostic (4.71e-2)" "unprognostic (3.34e-1)" "unprognostic (1.38e-1)" "unprognostic (2.64e-1)" "unprognostic (2.36e-1)" "unprognostic (1.02e-1)" "unprognostic (7.12e-3)" "unprognostic (1.51e-1)" "unprognostic (8.58e-2)" "unprognostic (1.87e-1)" "unprognostic (2.27e-1)" "unprognostic (4.87e-2)" "unprognostic (1.38e-1)" "unprognostic (5.17e-3)" "unprognostic (6.09e-2)" "unprognostic (3.07e-2)" "unprognostic (1.26e-1)" FEZ2 ENSG00000171055 "Fasciculation and elongation protein zeta 2" Q9UHY8 2 36531805-36646087 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epicardial cells: 818.7;Myonuclei: 416.9;Syncytiotrophoblasts: 472.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 15.6" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035978 Uncertain Approved "Nucleoli,Nucleoli rim,Golgi apparatus,Cytosol" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 72: Neuronal - Signal transduction" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 18 "Nucleoli, Nucleoli rim" "Golgi apparatus, Cytosol" "HPA035978: " "unprognostic (8.36e-3)" "unprognostic (4.84e-2)" "unprognostic (1.59e-1)" "unprognostic (2.32e-2)" "unprognostic (2.02e-1)" "unprognostic (1.01e-1)" "unprognostic (3.34e-2)" "unprognostic (4.22e-1)" "unprognostic (2.18e-3)" "unprognostic (1.23e-2)" "potential prognostic favorable (2.05e-6)" "unprognostic (3.04e-2)" "unprognostic (1.00e-1)" "potential prognostic unfavorable (9.86e-6)" "unprognostic (3.16e-2)" "potential prognostic unfavorable (1.35e-5)" "unprognostic (2.19e-2)" "unprognostic (1.65e-1)" "unprognostic (3.35e-1)" "unprognostic (3.52e-2)" "unprognostic (3.85e-3)" "unprognostic (5.04e-2)" "unprognostic (1.06e-2)" "unprognostic (9.89e-2)" "unprognostic (8.38e-2)" "unprognostic (3.09e-1)" "unprognostic (9.80e-2)" "unprognostic (2.46e-2)" "unprognostic (3.57e-2)" "unprognostic (1.58e-1)" "unprognostic (1.36e-1)" FEZF1 ZNF312B ENSG00000128610 "FEZ family zinc finger 1" A0PJY2 7 122301303-122310691 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 13.1;pituitary gland: 3.0;testis: 4.2" "Cell type enhanced" "Detected in some" "Gastric progenitor cells: 35.9;Late primary spermatocytes: 20.1;Oocytes: 4.6;Other brain neurons: 3.4;Pituicytes/FSCs: 9.2;Retinal bipolar cells: 6.3" "Cell type enhanced" "Detected in some" "amygdala excitatory: 1.4;astrocyte: 1.8;ependymal cell: 1.4;splatter: 1.0" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 38 "hypothalamus: 270.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 8 "Bone cancer: 53.3" "Testis - Early spermatids" "Region enriched" "Detected in some" 11 "hypothalamus: 11.7" "Region enriched" "Detected in single" 14 "hypothalamus: 9.6" "HPA064639, HPA073693" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 98: Neurons - Neurotransmission & signaling" 6 Nucleoplasm Cytosol "HPA064639: , HPA073693: " "unprognostic (1.59e-1)" "unprognostic (4.37e-2)" "unprognostic (1.79e-1)" "unprognostic (1.58e-3)" "unprognostic (3.60e-2)" "potential prognostic unfavorable (3.95e-5)" "unprognostic (3.36e-1)" "unprognostic (1.80e-1)" "unprognostic (6.46e-3)" "unprognostic (2.24e-3)" "potential prognostic favorable (2.44e-4)" "unprognostic (2.44e-1)" "unprognostic (3.74e-3)" "unprognostic (2.35e-1)" "unprognostic (6.66e-3)" "unprognostic (1.27e-1)" FEZF2 "FEZL, FKSG36, FLJ10142, TOF, Zfp312, ZNF312" ENSG00000153266 "FEZ family zinc finger 2" Q8TBJ5 3 62369681-62374324 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 25.8" "Cell type enhanced" "Detected in some" "Astrocytes: 8.3;Brain excitatory neurons: 8.7;Oocytes: 13.8;Retinal bipolar cells: 41.6" "Cell type enhanced" "Detected in some" "deep-layer corticothalamic and 6b: 36.5;deep-layer near-projecting: 53.8;hippocampal CA1-3: 51.6" "Group enriched" "Detected in some" 5 "Ovary Serous Cystadenocarcinoma (TCGA): 9.2;Stomach Adenocarcinoma (TCGA): 3.3" "Group enriched" "Detected in many" 6 "cerebral cortex: 329.8;hippocampal formation: 114.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Breast glandular cells (progenitors)" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "amygdala: 21.4;cerebral cortex: 21.8;hippocampal formation: 38.3" "HPA047169, HPA072981" Approved Nucleoplasm,Vesicles,Centrosome,Cytosol NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 1 "Nucleoplasm, Vesicles" "Centrosome, Cytosol" "HPA047169: , HPA072981: " "unprognostic (4.38e-2)" "unprognostic (3.18e-1)" "unprognostic (9.47e-2)" "unprognostic (3.37e-1)" "unprognostic (5.71e-2)" "unprognostic (1.05e-2)" FFAR1 "FFA1R, GPR40" ENSG00000126266 "Free fatty acid receptor 1" O14842 19 35347902-35353864 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 2.9;brain: 2.2;ovary: 2.5;pancreas: 2.4" "Cell type enriched" "Detected in some" 4 "Pancreatic islet cells: 34.2" "Group enriched" "Detected in some" 11 "committed oligodendrocyte precursor: 2.8;oligodendrocyte: 6.0" "Cancer enriched" "Detected in single" 9 "Pancreatic Adenocarcinoma (TCGA): 3.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.0" "Cancer enhanced" "Detected in single" "lymphoma: 1.3" "Pancreas - Beta cells" "Not detected" "Not detected" HPA048933 Supported "Plasma membrane" NA NA "Cluster 68: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" "Plasma membrane" "HPA048933: " "unprognostic (4.73e-2)" FFAR2 "FFA2R, GPR43" ENSG00000126262 "Free fatty acid receptor 2" O15552 19 35443907-35451767 "G-protein coupled receptors, Predicted membrane proteins" "Immunity, Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.1;lymphoid tissue: 21.0" "Cell type enriched" "Detected in some" 7 "Neutrophils: 314.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 8.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 25 "eosinophil: 85.0;neutrophil: 249.8" "Lineage enriched" "Detected in many" 38 "granulocytes: 249.8" "Cancer enhanced" "Detected in some" "Gastric cancer: 1.9;prostate cancer: 2.8" "Breast - Endothelial cells, Heart muscle - Neutrophils, Liver - Neutrophils, Pituitary gland - Neutrophils, Prostate - Prostate glandular cells, Skeletal muscle - Neutrophils, Spleen - Neutrophils_2, Stomach - Neutrophils, Thyroid gland - Neutrophils" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA023985 Approved NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 11: White matter - Signal transduction" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 93 "HPA023985: " "unprognostic (2.18e-1)" "unprognostic (1.91e-3)" "unprognostic (1.18e-2)" "unprognostic (3.90e-2)" "unprognostic (1.65e-3)" "unprognostic (1.59e-1)" "unprognostic (1.69e-2)" "unprognostic (3.77e-2)" "unprognostic (9.81e-2)" "unprognostic (1.36e-1)" "unprognostic (4.95e-1)" "unprognostic (5.67e-3)" "unprognostic (9.77e-2)" "unprognostic (1.90e-1)" "unprognostic (3.05e-2)" "unprognostic (4.34e-1)" "unprognostic (1.58e-1)" "unprognostic (1.48e-1)" FFAR3 "FFA3R, GPR41" ENSG00000185897 "Free fatty acid receptor 3" O14843 19 35358460-35360489 "G-protein coupled receptors, Predicted membrane proteins" "Immunity, Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 3.8;breast: 2.2;lymphoid tissue: 2.4" "Cell type enhanced" "Detected in some" "cDC: 1.8;Hofbauer cells: 1.1;Innate lymphoid cells: 4.2;Kupffer cells: 3.1;Macrophages: 2.0;Mast cells: 8.8;monocytes: 4.9;Neutrophils: 2.5;Pancreatic islet cells: 2.5;Parietal cells: 1.8;Pericytes: 1.6;T-cells: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 5 "eosinophil: 2.5;neutrophil: 2.8" "Lineage enriched" "Detected in single" 5 "granulocytes: 2.8" "Not detected" "Not detected" HPA044681 Uncertain NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 11: White matter - Signal transduction" "Cluster 50: Lymphoma - Unknown function" "Cluster 58: Mast cells - Allergic inflammatory responses" 12 "HPA044681: " "unprognostic (1.29e-1)" FFAR4 "GPR120, GPR129, O3FAR1, PGR4" ENSG00000186188 "Free fatty acid receptor 4" Q5NUL3 10 93566665-93604480 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "Differentiation, Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "adipose tissue: 3.8;intestine: 10.7;lung: 3.4;pituitary gland: 10.4" "Cell type enhanced" "Detected in some" "Adipocytes: 167.0;Corticotrophs: 30.4;Early spermatids: 66.0;Epicardial cells: 357.0;Goblet cells: 126.3;Microglia: 30.0;Somatotrophs: 111.5" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 36.7" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 7.3;Rectum Adenocarcinoma (TCGA): 5.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 4.3" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Macrophages, Breast - Adipocytes (Breast), Colon - Colon enterocytes, Pituitary gland - Corticotropes, Testis - Late spermatids, Thyroid gland - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA042563 Supported "Vesicles,Plasma membrane,Basal body" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 17: Intestine - Digestion" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 70: Intestinal goblet cells - Mucin production" "Plasma membrane" "Vesicles, Basal body" "HPA042563: " "unprognostic (8.43e-2)" "unprognostic (2.07e-3)" "unprognostic (1.68e-1)" "unprognostic (4.03e-1)" "unprognostic (2.93e-1)" "unprognostic (7.64e-2)" "unprognostic (5.70e-3)" "unprognostic (1.56e-1)" "unprognostic (3.24e-1)" "unprognostic (1.88e-1)" "unprognostic (1.29e-1)" "unprognostic (7.93e-2)" "unprognostic (8.04e-2)" FGA ENSG00000171560 "Fibrinogen alpha chain" P02671 4 154583126-154590742 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Adaptive immunity, Blood coagulation, Hemostasis, Immunity, Innate immunity" "Amyloidosis, Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 384 "liver: 17201.5" "Cell type enriched" "Detected in some" 44 "Hepatocytes: 17123.8" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 21 "Liver Hepatocellular Carcinoma (TCGA): 5313.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "liver cancer: 180.5" "Liver - Hepatocytes, Stomach - Parietal cells, Testis - Early spermatids, Testis - Late spermatids" "CAB016776, HPA051370, HPA064755" Supported Enhanced "Endoplasmic reticulum" "Secreted to blood" "Blood coagulation" NA NA 407000000 210000000000 "Cluster 53: Liver - Plasma proteins" "Cluster 18: Liver cancer - Metabolism" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 15 "Endoplasmic reticulum" "CAB016776: , HPA051370: , HPA064755: " "unprognostic (1.36e-1)" "unprognostic (4.10e-2)" "unprognostic (5.40e-2)" "unprognostic (2.33e-2)" "unprognostic (1.65e-2)" "unprognostic (1.41e-3)" "unprognostic (1.26e-3)" "unprognostic (2.52e-2)" "unprognostic (2.72e-1)" "potential prognostic unfavorable (3.10e-5)" "unprognostic (2.81e-1)" "unprognostic (1.59e-1)" "potential prognostic unfavorable (7.62e-6)" "unprognostic (7.32e-2)" "unprognostic (3.70e-1)" "unprognostic (2.73e-1)" "unprognostic (1.16e-1)" "unprognostic (4.56e-1)" FGB ENSG00000171564 "Fibrinogen beta chain" P02675 4 154563011-154572807 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Blood coagulation, Hemostasis, Immunity, Innate immunity" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 351 "liver: 16764.8" "Cell type enriched" "Detected in some" 76 "Hepatocytes: 17547.8" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 21 "Liver Hepatocellular Carcinoma (TCGA): 4509.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 8 "liver cancer: 219.4" "Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA001900, HPA001901, CAB008624" Enhanced Enhanced "Endoplasmic reticulum" "Secreted to blood" "Blood coagulation" NA NA 170000000000 "Cluster 53: Liver - Plasma proteins" "Cluster 18: Liver cancer - Metabolism" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 24 "Endoplasmic reticulum" "CAB008624: , HPA001900: , HPA001901: " "unprognostic (1.05e-3)" "unprognostic (8.75e-2)" "unprognostic (1.35e-2)" "unprognostic (1.84e-2)" "unprognostic (3.73e-3)" "unprognostic (1.02e-1)" "unprognostic (4.31e-2)" "unprognostic (4.17e-2)" "unprognostic (7.12e-3)" "potential prognostic favorable (7.15e-4)" "unprognostic (7.37e-3)" "unprognostic (1.02e-1)" "unprognostic (2.83e-1)" "unprognostic (8.27e-2)" "potential prognostic unfavorable (3.44e-9)" "unprognostic (1.46e-1)" "unprognostic (3.78e-1)" "unprognostic (2.40e-2)" "unprognostic (9.50e-2)" "unprognostic (1.01e-1)" FGD1 "FGDY, ZFYVE3" ENSG00000102302 "FYVE, RhoGEF and PH domain containing 1" P98174 X 54445454-54496234 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Retinal horizontal cells: 30.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 33.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000911, HPA076516" Approved Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 29: Forebrain - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 35: Neurons - Synaptic function & neurogenesis" 2 "Plasma membrane, Cytosol" "HPA000911: , HPA076516: " "unprognostic (4.63e-2)" "unprognostic (2.92e-1)" "unprognostic (8.95e-2)" "unprognostic (1.57e-1)" "unprognostic (1.81e-2)" "unprognostic (1.92e-2)" "unprognostic (3.29e-1)" "unprognostic (2.31e-3)" "unprognostic (1.59e-1)" "unprognostic (5.30e-3)" "unprognostic (5.54e-2)" "unprognostic (2.09e-3)" "potential prognostic unfavorable (6.91e-4)" "unprognostic (8.40e-3)" "unprognostic (4.53e-2)" "unprognostic (1.96e-2)" "potential prognostic unfavorable (8.38e-4)" "unprognostic (6.62e-2)" "unprognostic (1.97e-2)" "unprognostic (1.22e-1)" "unprognostic (7.19e-2)" "potential prognostic favorable (5.58e-4)" "unprognostic (1.55e-2)" "unprognostic (2.54e-1)" "unprognostic (2.04e-1)" "unprognostic (1.14e-2)" "unprognostic (5.71e-2)" "unprognostic (6.32e-3)" "unprognostic (4.07e-2)" "unprognostic (1.19e-2)" "unprognostic (1.98e-1)" FGD2 ZFYVE4 ENSG00000146192 "FYVE, RhoGEF and PH domain containing 2" Q7Z6J4 6 37005646-37029069 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 39.6" "Cell type enhanced" "Detected in many" "B-cells: 135.4;cDC: 154.3;Hofbauer cells: 49.6;Kupffer cells: 221.4;Macrophages: 165.4;Microglia: 284.7;Monocyte progenitors: 80.5;monocytes: 129.2;pDCs: 93.8" "Cell type enriched" "Detected in some" 6 "central nervous system macrophage: 327.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "classical monocyte: 22.7;intermediate monocyte: 65.6;memory B-cell: 24.0;myeloid DC: 35.5;naive B-cell: 19.1;non-classical monocyte: 72.0;plasmacytoid DC: 27.9" "Group enriched" "Detected in many" 18 "B-cells: 24.0;dendritic cells: 35.5;monocytes: 72.0" "Group enriched" "Detected in some" 7 "Leukemia: 3.4;lymphoma: 10.2;Myeloma: 3.2" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Testis - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA029145, HPA049692" Approved NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 5 "HPA029145: , HPA049692: " "unprognostic (2.32e-1)" "unprognostic (8.16e-2)" "unprognostic (3.07e-3)" "unprognostic (4.78e-2)" "unprognostic (5.72e-2)" "unprognostic (1.26e-1)" "unprognostic (8.72e-2)" "unprognostic (1.25e-1)" "unprognostic (1.10e-3)" "unprognostic (1.08e-2)" "unprognostic (3.03e-1)" "unprognostic (1.72e-2)" "unprognostic (9.46e-2)" "unprognostic (3.11e-2)" "unprognostic (4.90e-3)" "unprognostic (1.22e-1)" "unprognostic (9.88e-2)" "unprognostic (4.73e-2)" "unprognostic (4.41e-2)" "unprognostic (5.68e-3)" "unprognostic (5.48e-2)" "unprognostic (5.17e-2)" "unprognostic (3.82e-1)" "unprognostic (3.57e-2)" "unprognostic (5.15e-2)" "unprognostic (1.24e-2)" "unprognostic (2.74e-1)" "unprognostic (7.89e-3)" "unprognostic (1.59e-1)" FGD3 "FLJ00004, ZFYVE5" ENSG00000127084 "FYVE, RhoGEF and PH domain containing 3" Q5JSP0 9 92947523-93036236 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 37.3;lymphoid tissue: 32.5" "Cell type enhanced" "Detected in many" "Early spermatids: 113.5;Late spermatids: 227.5;Microglia: 84.4;Neutrophil progenitors: 217.7;Neutrophils: 683.2;NK-cells: 136.2;Oocytes: 87.5;T-cells: 113.5" "Group enriched" "Detected in many" 7 "central nervous system macrophage: 102.0;leukocyte: 187.7" "Cancer enhanced" "Detected in all" "Breast Invasive Carcinoma (TCGA): 27.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 23.9" "Pituitary gland - T-cells, Prostate - T-cells, Spleen - Neutrophils_2, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020963, HPA021018" Approved Approved Nucleoplasm,Cytosol NA NA 4400 "Cluster 35: Neutrophils - Protein binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 59: Leukemia - T-cell receptor" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 2 "Nucleoplasm, Cytosol" "HPA020963: , HPA021018: " "unprognostic (3.45e-3)" "unprognostic (3.51e-2)" "unprognostic (1.41e-2)" "unprognostic (4.37e-2)" "unprognostic (4.35e-3)" "unprognostic (2.74e-1)" "unprognostic (8.35e-2)" "unprognostic (9.46e-3)" "potential prognostic favorable (1.79e-7)" "unprognostic (6.73e-2)" "unprognostic (4.69e-2)" "unprognostic (1.79e-1)" "unprognostic (1.00e-1)" "unprognostic (1.79e-1)" "unprognostic (3.79e-2)" "unprognostic (2.13e-3)" "unprognostic (7.79e-2)" "unprognostic (1.50e-1)" "unprognostic (2.45e-1)" "unprognostic (2.54e-1)" "unprognostic (1.42e-1)" "unprognostic (1.01e-1)" "unprognostic (2.00e-2)" "unprognostic (3.71e-1)" "unprognostic (3.94e-1)" "unprognostic (4.28e-3)" "unprognostic (1.46e-2)" "unprognostic (1.96e-1)" "unprognostic (1.67e-1)" "unprognostic (1.57e-1)" "unprognostic (6.84e-2)" FGD4 "CMT4H, frabin, FRABP, ZFYVE6" ENSG00000139132 "FYVE, RhoGEF and PH domain containing 4" Q96M96 12 32399558-32646050 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin-binding, Guanine-nucleotide releasing factor" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 1393.7;Neutrophil progenitors: 1727.6;Neutrophils: 4466.3;Rod photoreceptor cells: 1140.4" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 1071.7" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 35.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 3.5;eosinophil: 8.2;intermediate monocyte: 5.8;myeloid DC: 3.4;neutrophil: 5.2;non-classical monocyte: 5.2" "Group enriched" "Detected in many" 6 "dendritic cells: 3.4;granulocytes: 8.2;monocytes: 5.8" "Low cancer specificity" "Detected in all" "Stomach - Parietal cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039235 Approved Approved "Actin filaments" No No "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 42: Retina - Visual perception" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" "Actin filaments" "HPA039235: " "unprognostic (5.62e-2)" "unprognostic (4.61e-2)" "unprognostic (6.23e-2)" "unprognostic (1.81e-3)" "unprognostic (2.65e-2)" "unprognostic (3.52e-1)" "unprognostic (3.51e-1)" "unprognostic (1.24e-1)" "unprognostic (1.71e-2)" "unprognostic (3.60e-3)" "potential prognostic favorable (1.16e-4)" "unprognostic (6.96e-2)" "unprognostic (1.60e-1)" "unprognostic (6.19e-3)" "potential prognostic favorable (8.05e-4)" "unprognostic (1.04e-1)" "unprognostic (2.16e-1)" "unprognostic (5.78e-3)" "unprognostic (4.17e-3)" "unprognostic (8.45e-2)" "unprognostic (1.61e-1)" "unprognostic (2.21e-3)" "unprognostic (1.02e-1)" "unprognostic (8.65e-2)" "unprognostic (4.24e-2)" "unprognostic (7.17e-2)" "unprognostic (1.34e-2)" "unprognostic (2.16e-1)" "unprognostic (1.16e-1)" "unprognostic (1.12e-1)" "unprognostic (3.60e-2)" FGD5 "FLJ00274, FLJ39957, ZFYVE23" ENSG00000154783 "FYVE, RhoGEF and PH domain containing 5" Q6ZNL6 3 14810853-14934571 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Corticotrophs: 54.7;Decidual stromal cells: 30.6;Fibro-adipogenic progenitors: 97.4;Fibroblasts: 34.3;Hematopoietic stem cells: 50.9;Hofbauer cells: 44.5;Leydig cells: 43.3;Lymphatic endothelial cells: 130.5;Proximal tubule cells: 71.7;Undifferentiated spermatogonia: 36.2;Vascular endothelial cells: 197.5" "Cell type enriched" "Detected in many" 4 "endothelial cell: 240.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 6.2;testis cancer: 6.1" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Breast - Endothelial cells, Heart muscle - Endothelial cells, Liver - Vascular endothelial cells, Pancreas - Endothelial cells, Skeletal muscle - Endothelial cells, Spleen - Endothelial cells, Stomach - Endothelial cells, Testis - Spermatogonia, Thyroid gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014436, HPA014536, HPA019191" Uncertain Supported "Plasma membrane" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 11 "Plasma membrane" "HPA014436: , HPA014536: , HPA019191: " "unprognostic (3.03e-1)" "unprognostic (1.58e-1)" "unprognostic (1.03e-1)" "unprognostic (9.08e-2)" "unprognostic (1.02e-1)" "unprognostic (1.68e-1)" "unprognostic (1.63e-1)" "unprognostic (2.99e-3)" "unprognostic (1.98e-2)" "unprognostic (1.80e-2)" "validated prognostic favorable (2.60e-9)" "validated prognostic favorable (6.45e-5)" "unprognostic (1.26e-1)" "unprognostic (2.04e-1)" "unprognostic (3.24e-2)" "unprognostic (2.05e-3)" "unprognostic (2.62e-2)" "unprognostic (2.87e-2)" "unprognostic (2.08e-1)" "unprognostic (9.67e-2)" "unprognostic (1.46e-1)" "unprognostic (1.90e-1)" "unprognostic (2.91e-1)" "unprognostic (2.05e-2)" "unprognostic (3.28e-1)" "unprognostic (2.46e-3)" "unprognostic (7.39e-2)" "unprognostic (2.82e-2)" "unprognostic (2.17e-1)" "unprognostic (1.41e-2)" "unprognostic (1.57e-1)" FGD6 "FLJ11183, ZFYVE24" ENSG00000180263 "FYVE, RhoGEF and PH domain containing 6" Q6ZV73 12 95076749-95217482 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 211.7;Syncytiotrophoblasts: 246.4" "Group enriched" "Detected in all" 4 "astrocyte: 122.1;endothelial cell: 349.0;fibroblast: 439.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 2.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007974 Approved Approved Vesicles NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 58: Skin - Keratinization" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 51: Secretory epithelial cells - Mixed function" 15 Vesicles "HPA007974: " "unprognostic (1.79e-1)" "unprognostic (1.99e-1)" "unprognostic (2.72e-2)" "unprognostic (6.60e-3)" "unprognostic (5.30e-2)" "unprognostic (9.94e-3)" "unprognostic (3.97e-1)" "unprognostic (1.94e-1)" "unprognostic (1.13e-1)" "unprognostic (2.53e-2)" "unprognostic (1.63e-1)" "unprognostic (1.11e-1)" "unprognostic (3.40e-2)" "unprognostic (2.37e-2)" "unprognostic (1.44e-1)" "unprognostic (9.92e-3)" "unprognostic (2.78e-3)" "unprognostic (2.31e-2)" "unprognostic (9.68e-2)" "unprognostic (1.97e-1)" "unprognostic (3.21e-3)" "potential prognostic unfavorable (9.52e-5)" "unprognostic (5.86e-3)" "unprognostic (1.43e-3)" "unprognostic (5.62e-2)" "unprognostic (1.10e-3)" "unprognostic (1.98e-3)" "unprognostic (8.39e-2)" "unprognostic (3.15e-2)" "unprognostic (2.91e-3)" FGF1 "AFGF, ECGF, ECGF-beta, ECGFA, ECGFB, FGF-alpha, FGFA, GLIO703, HBGF1" ENSG00000113578 "Fibroblast growth factor 1" P05230 5 142592178-142698070 "Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 282.0" "Group enriched" "Detected in many" 5 "Cone photoreceptor cells: 583.8;Podocytes: 2008.5;Rod photoreceptor cells: 523.2" "Cell type enhanced" "Detected in all" "fibroblast: 259.4;pericyte: 375.4;vascular associated smooth muscle cell: 234.3" "Cancer enriched" "Detected in many" 11 "Glioblastoma Multiforme (TCGA): 76.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Colon - Enteric glia cells, Kidney - Podocytes, Liver - Hepatic stellate cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003265, CAB017519" Enhanced Supported Nucleoplasm "Secreted in other tissues" "Growth factor" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 57: Podocytes - Glomerular filtration" 28 Nucleoplasm "CAB017519: , HPA003265: " "unprognostic (8.14e-2)" "unprognostic (3.53e-2)" "unprognostic (3.82e-1)" "unprognostic (1.52e-2)" "unprognostic (2.01e-1)" "unprognostic (6.06e-2)" "potential prognostic unfavorable (4.46e-4)" "unprognostic (1.67e-1)" "unprognostic (1.87e-1)" "validated prognostic favorable (2.26e-6)" "validated prognostic favorable (5.12e-4)" "unprognostic (8.56e-2)" "unprognostic (1.46e-2)" "unprognostic (3.31e-2)" "unprognostic (3.27e-2)" "unprognostic (2.15e-3)" "unprognostic (2.63e-2)" "potential prognostic unfavorable (1.17e-4)" "unprognostic (1.15e-1)" "unprognostic (1.70e-2)" "unprognostic (1.01e-1)" "unprognostic (4.07e-3)" "unprognostic (1.39e-1)" "unprognostic (3.17e-3)" "potential prognostic favorable (6.46e-5)" "unprognostic (4.32e-2)" FGF10 ENSG00000070193 "Fibroblast growth factor 10" O15520 5 44300247-44389706 "Disease related genes, Human disease related genes, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Disease variant, Ectodermal dysplasia, Lacrimo-auriculo-dento-digital syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 59.1;Decidual stromal cells: 37.0;Endometrial stromal cells: 109.5;Fibro-adipogenic progenitors: 154.5;Fibroblasts: 106.0;Leydig cells: 71.4;Ovarian stromal cells: 32.0;Pancreatic acinar cells: 36.1;Pericytes: 55.3;Peritubular myoid cells: 53.8;Pituicytes/FSCs: 116.5" "Cell type enhanced" "Detected in many" "fibroblast: 27.4" "Cancer enriched" "Detected in some" 6 "Breast Invasive Carcinoma (TCGA): 10.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Gastric cancer: 3.2;Neuroblastoma: 5.4;Sarcoma: 1.4" "Kidney - Fibroblasts, Lung - Fibroblasts_1, Prostate - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" CAB010315 Uncertain "Secreted in other tissues" "Growth factor" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 108: Fibroblasts - ECM organization" 6 "CAB010315: " "unprognostic (1.49e-1)" "unprognostic (1.74e-1)" "unprognostic (1.05e-1)" "unprognostic (1.24e-1)" "unprognostic (3.75e-2)" "unprognostic (6.23e-2)" "unprognostic (3.98e-3)" "unprognostic (3.79e-2)" FGF11 "FHF3, FLJ16061, MGC102953, MGC45269" ENSG00000161958 "Fibroblast growth factor 11" Q92914 17 7438273-7444937 "Predicted intracellular proteins" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 31.2" "Cell type enhanced" "Detected in some" "Astrocytes: 17.0;Bergmann glia: 8.5;Brain inhibitory neurons: 3.5;Loop of henle epithelial cells: 4.5;Oligodendrocyte progenitor cells: 7.7;Papillary tip epithelial cells: 1.8;Renal connecting tubule cells: 1.7" "Cell type enhanced" "Detected in many" "astrocyte: 17.9;midbrain-derived inhibitory: 25.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Endothelial cells, Heart muscle - Cardiomyocytes, Minor Salivary Gland - Minor salivary gland basal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066605, HPA075188" Enhanced Approved Centrosome NA NA "Cluster 68: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 28: Astrocytes - Homeostasis & neuron support" 9 Centrosome "HPA066605: , HPA075188: " "unprognostic (1.38e-2)" "unprognostic (3.64e-2)" "unprognostic (1.18e-1)" "unprognostic (8.17e-3)" "unprognostic (1.77e-1)" "unprognostic (1.30e-2)" "unprognostic (2.67e-1)" "unprognostic (3.70e-2)" "unprognostic (4.43e-3)" "unprognostic (1.68e-2)" "unprognostic (1.25e-2)" "unprognostic (4.64e-1)" "unprognostic (2.18e-1)" "unprognostic (2.40e-3)" "unprognostic (3.62e-3)" "unprognostic (2.86e-2)" "unprognostic (3.92e-2)" "unprognostic (2.30e-1)" "unprognostic (2.94e-1)" "unprognostic (1.11e-1)" "unprognostic (4.71e-3)" "unprognostic (1.56e-1)" "unprognostic (1.53e-1)" "unprognostic (1.22e-1)" "unprognostic (2.18e-1)" "unprognostic (9.47e-3)" "unprognostic (2.87e-1)" FGF12 "FGF12B, FHF1" ENSG00000114279 "Fibroblast growth factor 12" P61328 3 192139390-192767764 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Growth factor" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "heart muscle: 125.4" "Cell type enriched" "Detected in many" 4 "Cardiomyocytes: 9617.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 12.8" "Adrenal gland - Adrenal cortex cells, Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Minor Salivary Gland - Minor salivary glandular cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071557 Approved Nucleoplasm,Cytosol NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 14: Neurons - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 6 Nucleoplasm Cytosol "HPA071557: " "unprognostic (2.33e-1)" "unprognostic (2.58e-3)" "unprognostic (1.26e-2)" "unprognostic (8.42e-3)" "unprognostic (7.45e-2)" "potential prognostic favorable (7.25e-7)" "unprognostic (3.42e-2)" "unprognostic (1.23e-1)" "potential prognostic favorable (1.15e-8)" "unprognostic (3.59e-3)" "unprognostic (3.72e-3)" "unprognostic (9.32e-2)" "unprognostic (2.29e-3)" "unprognostic (3.38e-2)" "unprognostic (2.13e-2)" "unprognostic (2.90e-1)" "unprognostic (9.26e-2)" "unprognostic (2.81e-1)" "unprognostic (6.02e-2)" "unprognostic (4.54e-2)" "unprognostic (2.96e-1)" "unprognostic (9.77e-2)" "potential prognostic unfavorable (9.89e-4)" "unprognostic (5.94e-2)" "unprognostic (5.92e-2)" "unprognostic (5.14e-2)" FGF13 "FGF2, FHF2, FLJ30672, LINC00889" ENSG00000129682 "Fibroblast growth factor 13" Q92913 X 138614727-139222777 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Neurogenesis "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 64.9;skeletal muscle: 51.9;tongue: 41.3" "Cell type enhanced" "Detected in many" "Corticotrophs: 433.2;Distal convoluted tubule cells: 938.3;Endometrial glandular cells: 817.0;Endometrial luminal cells: 447.8;Epididymal clear cells: 741.0;Hofbauer cells: 505.2;Myonuclei: 946.4;Prostatic glandular cells: 782.8;Salivary acinar cells: 562.4" "Cell type enhanced" "Detected in all" "LAMP5-LHX6 and Chandelier: 1825.8" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 34.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 3.4" "Lineage enriched" "Detected in single" 8 "granulocytes: 3.4" "Low cancer specificity" "Detected in many" "Colon - Colon enteroendocrine cells, Heart muscle - Smooth muscle cells, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" HPA002809 Supported Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 29: Forebrain - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 51: Secretory epithelial cells - Mixed function" 5 Cytosol "HPA002809: " "unprognostic (8.95e-2)" "unprognostic (3.01e-1)" "unprognostic (1.99e-1)" "unprognostic (2.68e-1)" "unprognostic (3.99e-2)" "unprognostic (4.71e-1)" "unprognostic (1.52e-1)" "potential prognostic favorable (3.43e-6)" "unprognostic (7.86e-3)" "unprognostic (5.63e-2)" "unprognostic (2.50e-3)" "unprognostic (1.52e-3)" "unprognostic (1.25e-1)" "unprognostic (1.65e-2)" "unprognostic (1.82e-1)" "unprognostic (3.42e-3)" "unprognostic (2.05e-2)" "unprognostic (1.85e-2)" "unprognostic (1.52e-1)" "unprognostic (2.86e-2)" "unprognostic (1.58e-1)" "unprognostic (6.94e-3)" "unprognostic (1.11e-1)" "unprognostic (5.80e-2)" "unprognostic (2.56e-2)" "unprognostic (6.35e-2)" "unprognostic (1.26e-1)" "unprognostic (3.70e-3)" "unprognostic (1.17e-1)" "unprognostic (1.44e-1)" "unprognostic (8.28e-2)" FGF14 "FHF4, SCA27" ENSG00000102466 "Fibroblast growth factor 14" Q92915 13 101710804-102402457 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Growth factor" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.6;cervix: 5.5" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 1489.2;Bergmann glia: 4868.1;Brain excitatory neurons: 2868.2;Brain inhibitory neurons: 2907.9;Ependymal cells: 863.3;Oligodendrocyte progenitor cells: 2827.5;Other brain neurons: 1401.8;Respiratory ciliated cells: 854.5;Retinal horizontal cells: 855.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Kidney Chromophobe (TCGA): 5.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 2.2;Neuroblastoma: 4.0" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Adrenal medulla cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Spleen - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049828 Approved "Nucleoli fibrillar center" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 2: Neurons - Nucleosome" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 2 "Nucleoli fibrillar center" "HPA049828: " "unprognostic (7.59e-3)" "unprognostic (4.54e-2)" "unprognostic (5.34e-2)" "unprognostic (2.41e-1)" "unprognostic (1.26e-2)" "unprognostic (1.66e-2)" "unprognostic (8.75e-2)" FGF16 MF4 ENSG00000196468 "Fibroblast growth factor 16" O43320 X 77447389-77457278 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "choroid plexus: 4.2" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 1.6;Fibro-adipogenic progenitors: 3.5;Fibroblasts: 1.1;Hematopoietic stem cells: 1.5;Salivary ionocytes: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in some" "choroid plexus: 3.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 14 "Sarcoma: 1.4" "Thyroid gland - Fibroblasts" "Group enriched" "Detected in some" 6 "basal ganglia: 3.6;hippocampal formation: 2.0;olfactory bulb: 6.7" "Not detected" "Not detected" "Secreted in other tissues" "Growth factor" NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 6 "unprognostic (2.57e-1)" FGF17 FGF-13 ENSG00000158815 "Fibroblast growth factor 17" O60258 8 22042398-22048809 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins, RAS pathway related proteins" "Developmental protein, Growth factor" "Cancer-related genes, Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "brain: 81.7" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 12.2;Brain inhibitory neurons: 12.1;Choroid plexus epithelial cells: 3.7;Cone photoreceptor cells: 8.3;Other brain neurons: 8.6;Retinal amacrine cells: 6.3;Retinal bipolar cells: 5.7;Retinal pigment epithelial cells: 4.3;Thyrotrophs: 3.4" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in some" 9 "Ovary Serous Cystadenocarcinoma (TCGA): 8.6;Testicular Germ Cell Tumor (TCGA): 15.7;Uterine Corpus Endometrial Carcinoma (TCGA): 5.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 4 "basal ganglia: 2.1" "Low region specificity" "Detected in some" HPA052600 Uncertain "Secreted in brain" "Growth factor" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 37: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 109: Neurons - Neuronal signaling" 1 "HPA052600: " "unprognostic (3.39e-1)" "unprognostic (5.57e-3)" "potential prognostic favorable (6.99e-4)" "unprognostic (1.33e-1)" "unprognostic (1.22e-1)" "unprognostic (3.33e-1)" "unprognostic (1.53e-1)" "unprognostic (1.26e-1)" FGF18 "FGF-18, ZFGF5" ENSG00000156427 "Fibroblast growth factor 18" O76093 5 171419647-171457626 "Cancer-related genes, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 15.1" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 41.3;Endometrial glandular cells: 19.7;Endometrial luminal cells: 61.9;Endometrial secretory cells: 20.1;Fallopian secretory cells: 17.8" "Cell type enhanced" "Detected in some" "endothelial cell: 6.0" "Group enriched" "Detected in many" 5 "Ovary Serous Cystadenocarcinoma (TCGA): 27.3;Uterine Corpus Endometrial Carcinoma (TCGA): 29.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "ovarian cancer: 35.7;Uterine cancer: 29.3" "Prostate - Smooth muscle cells, Skeletal muscle - Fibroblasts, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in some" "cerebral cortex: 3.1" HPA018795 Uncertain "Secreted in other tissues" "Growth factor" NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 20: Non-specific - Transcription regulation" "HPA018795: " "unprognostic (3.59e-1)" "unprognostic (1.02e-1)" "unprognostic (1.37e-1)" "unprognostic (9.33e-2)" "unprognostic (2.91e-1)" "potential prognostic favorable (9.83e-4)" "unprognostic (1.27e-3)" "unprognostic (2.28e-1)" "unprognostic (1.19e-2)" "unprognostic (4.10e-2)" "unprognostic (4.19e-2)" "unprognostic (1.11e-2)" "unprognostic (4.56e-3)" "unprognostic (7.60e-2)" "unprognostic (4.34e-1)" "unprognostic (2.42e-1)" "unprognostic (2.70e-2)" FGF19 ENSG00000162344 "Fibroblast growth factor 19" O95750 11 69698238-69704022 "Cancer-related genes, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "gallbladder: 222.8" "Group enriched" "Detected in some" 4 "Cholangiocytes: 17.5;Enterocytes: 14.1;Epididymal basal cells: 21.5;Epididymal efferent duct absorptive cells: 8.6;Pancreatic duct cells: 9.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 31.1;Gastric cancer: 26.0" "Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" HPA036082 Approved "Secreted to blood" "Growth factor" NA NA 133000 "Cluster 13: Lung - Secretion" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 1: Enterocytes - Absorption and Digestion" 2 "HPA036082: " "unprognostic (2.55e-1)" "unprognostic (4.84e-1)" "unprognostic (3.83e-2)" "unprognostic (3.05e-1)" "unprognostic (3.94e-2)" "unprognostic (4.50e-3)" "unprognostic (6.17e-2)" "unprognostic (1.07e-1)" "unprognostic (1.61e-3)" "unprognostic (4.12e-1)" "unprognostic (1.80e-1)" "unprognostic (2.07e-1)" "unprognostic (1.05e-2)" "unprognostic (1.29e-2)" "unprognostic (1.88e-1)" "unprognostic (2.50e-3)" "unprognostic (1.41e-2)" "unprognostic (5.84e-3)" "unprognostic (2.12e-2)" FGF2 FGFB ENSG00000138685 "Fibroblast growth factor 2" P09038 4 122826682-122898236 "Cancer-related genes, Candidate cardiovascular disease genes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins, Transporters" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 117.1;Astrocytes: 166.7;Bergmann glia: 177.9;Choroid plexus epithelial cells: 183.7;Endometrial stromal cells: 87.4;Ependymal cells: 80.4;Fibroblasts: 168.1;Pituicytes/FSCs: 69.7;Retinal pigment epithelial cells: 132.2;Schwann cells: 129.6" "Cell type enhanced" "Detected in all" "astrocyte: 189.6;Bergmann glia: 186.9;choroid plexus epithelial cell: 151.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells, Skeletal muscle - Endothelial cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000125, HPA065502" Enhanced Supported "Nucleoplasm,Nuclear bodies" "Secreted in other tissues" "Growth factor" NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 46: Brainstem - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 17: Non-specific - RNA processing" 21 "Nucleoplasm, Nuclear bodies" "CAB000125: , HPA065502: " "unprognostic (8.59e-3)" "unprognostic (4.34e-3)" "unprognostic (4.75e-2)" "unprognostic (2.44e-1)" "unprognostic (7.71e-2)" "unprognostic (2.77e-2)" "unprognostic (3.35e-1)" "unprognostic (1.14e-1)" "unprognostic (3.02e-1)" "unprognostic (1.96e-1)" "unprognostic (7.68e-2)" "unprognostic (2.58e-1)" "unprognostic (1.33e-1)" "unprognostic (9.18e-2)" "unprognostic (7.38e-2)" "unprognostic (4.88e-2)" "unprognostic (3.85e-3)" "unprognostic (1.66e-1)" "potential prognostic unfavorable (5.26e-4)" "unprognostic (1.14e-1)" "unprognostic (2.06e-1)" "unprognostic (1.49e-2)" "unprognostic (2.74e-1)" "unprognostic (4.48e-2)" "unprognostic (2.11e-1)" "unprognostic (1.53e-1)" "unprognostic (3.29e-1)" FGF20 ENSG00000078579 "Fibroblast growth factor 20" Q9NP95 8 16992181-17002345 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.7" "Cell type enriched" "Detected in some" 6 "Microglia: 76.4" "Cell type enriched" "Detected in some" 14 "central nervous system macrophage: 97.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 17.9;Rhabdoid: 5.0" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "cerebellum: 2.5" "Secreted in other tissues" "Growth factor" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 25: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" "unprognostic (1.64e-1)" "unprognostic (3.52e-1)" "unprognostic (9.56e-2)" "unprognostic (4.73e-2)" "unprognostic (1.03e-1)" "unprognostic (2.00e-1)" "unprognostic (2.19e-1)" "unprognostic (5.22e-2)" "unprognostic (2.13e-2)" "unprognostic (1.50e-1)" "unprognostic (3.81e-2)" "unprognostic (5.29e-3)" FGF21 ENSG00000105550 "Fibroblast growth factor 21" Q9NSA1 19 48755524-48758333 "Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 105 "liver: 79.4" "Group enriched" "Detected in some" 32 "Cholangiocytes: 2.0;Hepatocytes: 7.7" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 361 "Liver Hepatocellular Carcinoma (TCGA): 68.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Esophageal cancer: 1.6;Rhabdoid: 1.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA061286 Supported "Secreted to blood" "Growth factor" NA NA 254000 590000 "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 13: Non-specific - Mixed function" "Cluster 93: Hepatocytes - Bile production & excretion" 6 "HPA061286: " "unprognostic (4.49e-2)" "unprognostic (2.51e-3)" FGF22 ENSG00000070388 "Fibroblast growth factor 22" Q9HCT0 19 639879-644373 "Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.6;skin 1: 13.0" "Cell type enhanced" "Detected in some" "Astrocytes: 5.3;Brain excitatory neurons: 4.7;Brain inhibitory neurons: 4.2;Esophageal apical cells: 7.3;Medullary thymic epithelial cells: 4.8;Müller glia: 6.1;Other brain neurons: 5.8;Ovarian stromal cells: 8.4;Retinal amacrine cells: 9.2;Retinal horizontal cells: 12.0;Syncytiotrophoblasts: 6.6" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted in other tissues" "Growth factor" NA NA "Cluster 2: Non-specific - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" "unprognostic (8.17e-2)" FGF23 ENSG00000118972 "Fibroblast growth factor 23" Q9GZV9 12 4368227-4379712 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, RAS pathway related proteins, Transporters" Differentiation "Growth factor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 5.4;liver: 4.7" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 2.1;Early primary spermatocytes: 1.3;Early spermatids: 5.1;Epicardial cells: 2.3;Late primary spermatocytes: 6.5;Late spermatids: 2.8;Retinal horizontal cells: 2.0;Undifferentiated spermatogonia: 1.3" "Low cell type specificity" "Detected in some" "Group enriched" "Detected in many" 4 "Ovary Serous Cystadenocarcinoma (TCGA): 20.5;Stomach Adenocarcinoma (TCGA): 53.2" "Group enriched" "Detected in many" 6 "cerebral cortex: 105.3;choroid plexus: 69.3;midbrain: 27.6" "Immune cell enhanced" "Detected in all" "basophil: 9.0" "Lineage enriched" "Detected in all" 4 "granulocytes: 9.0" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA048995 Approved "Nuclear bodies,Vesicles,Centrosome,Cytosol" "Secreted to blood" "Growth factor" NA NA 56800 30000 "Cluster 35: Neutrophils - Protein binding" "Cluster 76: Non-specific - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" 5 Vesicles "Nuclear bodies, Centrosome, Cytosol" "HPA048995: " "unprognostic (2.68e-1)" "unprognostic (3.37e-3)" "unprognostic (1.44e-1)" "unprognostic (1.57e-1)" "unprognostic (7.33e-2)" "unprognostic (3.33e-2)" "unprognostic (1.71e-1)" "unprognostic (2.10e-1)" "unprognostic (1.73e-1)" "unprognostic (2.89e-2)" "unprognostic (3.41e-2)" "unprognostic (9.61e-2)" "unprognostic (3.13e-2)" "unprognostic (5.86e-2)" "unprognostic (8.04e-2)" "unprognostic (1.60e-3)" "unprognostic (8.08e-2)" "unprognostic (2.27e-1)" "unprognostic (1.91e-1)" "unprognostic (9.88e-3)" "unprognostic (2.46e-1)" FGF3 "HBGF-3, INT2" ENSG00000186895 "Fibroblast growth factor 3" P11487 11 69809968-69819416 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins, RAS pathway related proteins" Differentiation "Developmental protein, Growth factor, Mitogen" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 53 "brain: 5.2" "Cell type enriched" "Detected in single" 8 "Brain excitatory neurons: 2.2" "Cell type enriched" "Detected in single" 21 "upper rhombic lip: 3.5" "Cancer enhanced" "Detected in some" "Stomach Adenocarcinoma (TCGA): 2.3" "Region enriched" "Detected in some" 6 "cerebellum: 7.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 13 "cervical cancer: 21.5" "Region enhanced" "Detected in some" "basal ganglia: 3.1" "Not detected" "Not detected" HPA012692 Enhanced "Secreted in brain" "Growth factor" NA NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 32: Non-specific - Cell proliferation" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 1 "HPA012692: " "unprognostic (1.21e-1)" "unprognostic (4.61e-1)" FGF4 "HBGF-4, HST, HST-1, HSTF1, K-FGF, KFGF" ENSG00000075388 "Fibroblast growth factor 4" P08620 11 69771022-69775341 "Cancer-related genes, Predicted secreted proteins, RAS pathway related proteins" Differentiation "Developmental protein, Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Early spermatids: 2.6;Late primary spermatocytes: 2.4;Late spermatids: 1.5" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Testicular Germ Cell Tumor (TCGA): 19.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "breast cancer: 1.4;Gastric cancer: 3.3;liver cancer: 2.1;testis cancer: 5.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA011209 Uncertain "Secreted in other tissues" "Growth factor" NA NA "Cluster 32: Non-specific - Cell proliferation" "Cluster 110: Mural cells - ECM organization" 22 "HPA011209: " "unprognostic (1.10e-1)" "unprognostic (5.47e-1)" FGF5 ENSG00000138675 "Fibroblast growth factor 5" P12034 4 80266639-80336680 "Disease related genes, Human disease related genes, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Mitogen" "Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.8;gallbladder: 2.6;intestine: 1.1" "Group enriched" "Detected in some" 5 "Brain excitatory neurons: 28.9;Undifferentiated spermatogonia: 18.5" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 67.8;hippocampal CA4: 103.2;lower rhombic lip: 62.4;upper rhombic lip: 67.6" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebellum: 24.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "thyroid cancer: 19.3" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Skin - Hair cortex cells, Skin - Inner root sheath cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "Secreted in brain" "Growth factor" NA NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 1 "unprognostic (4.11e-2)" FGF6 ENSG00000111241 "Fibroblast growth factor 6" P10767 12 4428155-4445815 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Mitogen" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 21 "skeletal muscle: 12.9;tongue: 8.9" "Cell type enriched" "Detected in some" 14 "Myonuclei: 34.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 12 "Leukemia: 3.5" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" "Growth factor" NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 53: Neurons - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 1 FGF7 KGF ENSG00000140285 "Fibroblast growth factor 7" P21781 15 49423237-49488775 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Heparin-binding, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 65.8;Decidual stromal cells: 160.9;Fibro-adipogenic progenitors: 245.6;Fibroblasts: 356.5;Leydig cells: 108.0;Ovarian stromal cells: 64.6;Pericytes: 163.6;Salivary myoepithelial cells: 101.4;Smooth muscle cells: 166.5" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 6.3;fibroblast: 7.4" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 35.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 11.7" "Heart muscle - Macrophages, Prostate - Fibroblasts, Skin - Endothelial cells" "Region enriched" "Detected in some" 6 "cerebellum: 8.7" "Group enriched" "Detected in all" 5 "hippocampal formation: 20.1;spinal cord: 9.6" HPA043605 Uncertain Approved Nucleoplasm,Nucleoli "Secreted in other tissues" "Growth factor" NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 103: Non-specific - Basic cellular processes" 2 "Nucleoplasm, Nucleoli" "HPA043605: " "unprognostic (1.70e-3)" "unprognostic (4.81e-1)" "unprognostic (9.92e-2)" "unprognostic (8.36e-2)" "unprognostic (1.58e-1)" "unprognostic (1.39e-2)" "unprognostic (1.66e-1)" "unprognostic (7.28e-2)" "unprognostic (6.20e-2)" "unprognostic (6.09e-2)" "unprognostic (1.39e-2)" "potential prognostic unfavorable (7.12e-5)" "unprognostic (1.05e-2)" "unprognostic (4.58e-2)" "unprognostic (3.88e-2)" "unprognostic (5.82e-3)" "unprognostic (1.54e-1)" "unprognostic (3.14e-2)" "unprognostic (8.67e-3)" "unprognostic (2.38e-2)" "unprognostic (9.87e-2)" "unprognostic (1.47e-1)" "unprognostic (1.92e-1)" "unprognostic (1.06e-2)" "unprognostic (1.24e-1)" "unprognostic (3.12e-3)" "unprognostic (2.33e-1)" "potential prognostic unfavorable (6.38e-4)" "unprognostic (1.82e-1)" FGF8 AIGF ENSG00000107831 "Fibroblast growth factor 8" P55075 10 101770109-101780371 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" Differentiation "Developmental protein, Growth factor, Mitogen" "Cancer-related genes, Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 45 "skeletal muscle: 33.3" "Cell type enhanced" "Detected in some" "Adipocytes: 2.8;Breast myoepithelial cells: 1.7;Cholangiocytes: 1.3;Myosatellite cells: 1.2;Retinal ganglion cells: 3.9" "Cell type enhanced" "Detected in some" "hippocampal CA1-3: 2.4" "Group enriched" "Detected in some" 5 "Bladder Urothelial Carcinoma (TCGA): 3.5;Testicular Germ Cell Tumor (TCGA): 7.7;Uterine Corpus Endometrial Carcinoma (TCGA): 6.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in some" 4 "Sarcoma: 14.3" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" "Growth factor" NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 29: Forebrain - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 89: Adipocytes - Lipid metabolism" 2 "unprognostic (6.88e-3)" "unprognostic (4.62e-2)" "unprognostic (3.63e-2)" "unprognostic (1.87e-1)" "unprognostic (3.59e-1)" FGF9 ENSG00000102678 "Fibroblast growth factor 9" P31371 13 21671073-21704498 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" Differentiation "Developmental protein, Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 11.0;kidney: 10.0;retina: 7.6" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 64.8;Distal convoluted tubule cells: 99.5;Endometrial luminal cells: 67.9;Loop of henle epithelial cells: 77.0;Mesothelial cells: 56.6;Müller glia: 223.3;Renal collecting duct intercalated cells: 129.5;Retinal ganglion cells: 96.6;Retinal horizontal cells: 54.1;Somatotrophs: 49.6" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in some" 5 "Kidney Chromophobe (TCGA): 26.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 4.0" "Adipose visceral - Mesothelial cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067007 Enhanced Approved "Secreted in other tissues" "Growth factor" NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 37: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 11: Muller glia cells - Retinal homeostasis" 1 "HPA067007: " "potential prognostic favorable (1.43e-4)" "unprognostic (5.94e-2)" "unprognostic (3.47e-1)" "unprognostic (1.56e-3)" "unprognostic (1.04e-1)" FGFBP1 "FGFBP, HBP17" ENSG00000137440 "Fibroblast growth factor binding protein 1" Q14512 4 15935577-15938740 "Cancer-related genes, Predicted secreted proteins" "Growth factor binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 126.2;esophagus: 412.9;vagina: 167.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 892.8;Esophageal apical cells: 998.2;Esophageal basal cells: 763.9;Esophageal suprabasal cells: 1381.5;Ocular epithelial cells: 1337.7;Respiratory deuterosomal cells: 322.4;Respiratory secretory cells: 273.1;Salivary duct cells: 571.8;Suprabasal keratinocytes: 1091.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 179.1;Head and Neck Squamous Cell Carcinoma (TCGA): 368.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 379.0;head and neck cancer: 386.0" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary gland basal cells" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA004332 Enhanced "Secreted in other tissues" Other NA NA 17000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 152 "HPA004332: " "unprognostic (9.14e-3)" "potential prognostic favorable (6.48e-4)" "unprognostic (1.76e-1)" "unprognostic (1.47e-1)" "unprognostic (1.34e-1)" "unprognostic (2.53e-1)" "unprognostic (5.61e-2)" "unprognostic (1.17e-1)" "unprognostic (1.30e-3)" "unprognostic (8.68e-2)" "unprognostic (1.19e-1)" "unprognostic (8.84e-2)" "unprognostic (2.14e-1)" "unprognostic (7.28e-2)" "potential prognostic unfavorable (1.08e-4)" "unprognostic (6.97e-2)" "unprognostic (4.74e-2)" "unprognostic (5.75e-2)" "unprognostic (2.02e-1)" "unprognostic (3.07e-1)" "unprognostic (3.12e-2)" "unprognostic (2.30e-1)" "unprognostic (5.48e-3)" FGFBP2 KSP37 ENSG00000137441 "Fibroblast growth factor binding protein 2" Q9BYJ0 4 15960245-15969309 "Plasma proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 27.5;bone marrow: 51.4" "Group enriched" "Detected in some" 4 "Melanocytes: 96.2;NK-cells: 326.0;Schwann cells: 112.0" "Cell type enriched" "Detected in single" 105 "leukocyte: 65.7" "Group enriched" "Detected in many" 4 "Head and Neck Squamous Cell Carcinoma (TCGA): 23.0;Lung Squamous Cell Carcinoma (TCGA): 60.0;Skin Cutaneous Melanoma (TCGA): 35.0" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "gdT-cell: 552.5;memory CD8 T-cell: 331.9" "Lineage enriched" "Detected in many" 8 "T-cells: 552.5" "Group enriched" "Detected in some" 16 "Rhabdoid: 72.7;skin cancer: 19.0" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Enteric glia cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Skeletal muscle - Fibroblasts, Spleen - NK-cells (Spleen)" "Secreted to blood" Other NA NA 346000000 3500000 "Cluster 24: Non-specific - Transcription" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 5: Rhabdoid - Unknown function" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 1 "unprognostic (5.68e-2)" "unprognostic (7.99e-3)" "unprognostic (8.28e-3)" "unprognostic (3.04e-2)" "unprognostic (6.31e-2)" "unprognostic (1.62e-1)" "potential prognostic favorable (3.02e-5)" "unprognostic (3.70e-2)" "unprognostic (5.54e-2)" "unprognostic (2.86e-2)" "unprognostic (6.10e-2)" "unprognostic (8.90e-2)" "unprognostic (2.17e-1)" "unprognostic (1.83e-1)" "unprognostic (2.84e-2)" FGFBP3 "C10orf13, MGC39320" ENSG00000174721 "Fibroblast growth factor binding protein 3" Q8TAT2 10 91906584-91909486 "Predicted secreted proteins" "Growth factor binding, Heparin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.2" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 16.0;Müller glia: 21.9;Neuroendocrine cells: 16.3" "Cell type enhanced" "Detected in many" "oligodendrocyte precursor cell: 14.7" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 7.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.7" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in many" 15 "Rhabdoid: 67.1" "Pituitary gland - Undifferentiated cells (Pituitary gland)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA053943 Uncertain "Secreted in brain" Other NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 11: Muller glia cells - Retinal homeostasis" "HPA053943: " "unprognostic (2.21e-2)" "unprognostic (1.20e-1)" "unprognostic (2.29e-1)" "unprognostic (1.81e-2)" "unprognostic (3.31e-2)" "unprognostic (3.03e-1)" "unprognostic (1.97e-2)" "potential prognostic favorable (9.04e-4)" "unprognostic (3.71e-2)" "unprognostic (1.65e-1)" "unprognostic (4.56e-3)" "unprognostic (1.50e-1)" "unprognostic (2.67e-2)" "unprognostic (5.03e-2)" "unprognostic (4.69e-2)" "unprognostic (1.68e-1)" "unprognostic (1.62e-1)" "unprognostic (1.08e-1)" FGFR1 "BFGFR, CD331, CEK, FLG, FLT2, H2, H3, H4, H5, KAL2, N-SAM" ENSG00000077782 "Fibroblast growth factor receptor 1" P11362 8 38400215-38468834 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Transcription, Transcription regulation" "Heparin-binding, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Disease variant, Dwarfism, FDA approved drug targets, Holoprosencephaly, Hypogonadotropic hypogonadism, Intellectual disability, Kallmann syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 302.0;Fibro-adipogenic progenitors: 280.7;Fibroblasts: 375.3;Leydig cells: 296.1;Pancreatic acinar cells: 541.7;Salivary myoepithelial cells: 296.6;Smooth muscle cells: 279.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in all" "Rhabdoid: 200.8" "Breast - Fibroblasts, Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009029, CAB033614, HPA056402" Approved Approved "Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Centriolar satellite,Basal body,Cytosol" Yes NA 13000000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 44: Non-specific - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 103: Non-specific - Basic cellular processes" 93 "Microtubules, Cytokinetic bridge, Mitotic spindle" "Primary cilium, Centriolar satellite, Basal body, Cytosol" "CAB033614: , HPA009029: , HPA056402: " "unprognostic (1.44e-1)" "unprognostic (7.85e-2)" "unprognostic (2.49e-1)" "unprognostic (2.05e-1)" "unprognostic (1.29e-1)" "unprognostic (6.62e-2)" "unprognostic (1.11e-2)" "unprognostic (3.70e-3)" "unprognostic (1.33e-1)" "unprognostic (2.20e-1)" "unprognostic (1.00e-2)" "unprognostic (4.48e-3)" "unprognostic (5.05e-2)" "unprognostic (2.58e-1)" "unprognostic (5.19e-2)" "unprognostic (5.23e-2)" "unprognostic (2.72e-1)" "unprognostic (1.08e-1)" "unprognostic (4.90e-2)" "unprognostic (1.16e-1)" "unprognostic (4.08e-2)" "unprognostic (3.39e-2)" "unprognostic (5.52e-2)" "unprognostic (4.75e-2)" "unprognostic (1.02e-1)" "unprognostic (5.74e-2)" "unprognostic (1.83e-1)" "unprognostic (4.24e-3)" "unprognostic (8.84e-2)" "unprognostic (9.56e-3)" "unprognostic (8.24e-2)" FGFR1OP2 DKFZp564O1863 ENSG00000111790 "FGFR1 oncogene partner 2" Q9NVK5 12 26938470-26966650 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Platelets: 258.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038308, HPA038696" Supported Approved Mitochondria NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 53: Neurons - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 32 Mitochondria "HPA038308: , HPA038696: " "unprognostic (1.66e-2)" "unprognostic (2.68e-1)" "unprognostic (6.75e-2)" "unprognostic (2.30e-1)" "unprognostic (2.12e-1)" "unprognostic (2.30e-3)" "unprognostic (1.99e-1)" "unprognostic (4.69e-3)" "unprognostic (2.23e-1)" "unprognostic (1.87e-2)" "potential prognostic favorable (2.35e-4)" "unprognostic (7.81e-3)" "unprognostic (6.50e-2)" "unprognostic (1.76e-3)" "unprognostic (1.67e-1)" "unprognostic (3.82e-1)" "unprognostic (3.07e-3)" "unprognostic (7.39e-2)" "unprognostic (1.95e-1)" "unprognostic (6.97e-3)" "unprognostic (7.93e-2)" "unprognostic (2.32e-1)" "potential prognostic unfavorable (2.83e-4)" "unprognostic (3.71e-2)" "unprognostic (6.41e-2)" "unprognostic (1.60e-1)" "unprognostic (2.22e-2)" "unprognostic (1.79e-2)" "unprognostic (1.85e-1)" "unprognostic (3.61e-1)" "unprognostic (5.66e-2)" FGFR2 "BEK, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25" ENSG00000066468 "Fibroblast growth factor receptor 2" P21802 10 121478332-121598458 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Apoptosis "Heparin-binding, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Disease variant, Ectodermal dysplasia, FDA approved drug targets, Intellectual disability, Lacrimo-auriculo-dento-digital syndrome, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 549.0" "Cell type enhanced" "Detected in many" "Bergmann glia: 1332.0;Cholangiocytes: 631.0;Choroid plexus epithelial cells: 1986.7;Gastric progenitor cells: 856.2;Oligodendrocytes: 629.1" "Group enriched" "Detected in many" 4 "Bergmann glia: 1277.6;choroid plexus epithelial cell: 1305.0;oligodendrocyte: 929.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "basophil: 3.0;eosinophil: 2.0" "Lineage enriched" "Detected in single" 28 "granulocytes: 3.0" "Cancer enhanced" "Detected in many" "Gastric cancer: 171.5" "Adipose visceral - Mesothelial cells, Breast - Breast myoepithelial cells, Kidney - Macrophages, Liver - Hepatic stellate cells, Lung - Alveolar cells type 2, Pituitary gland - Undifferentiated cells (Pituitary gland), Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010886, HPA035305" Uncertain Approved "Nucleoplasm,Vesicles,Cell Junctions" "Secreted - unknown location" Receptor NA NA 360000 "Cluster 46: Basophils - Proteolysis" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 40: Non-specific - Unknown function" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 34 "Cell Junctions" "Nucleoplasm, Vesicles" "CAB010886: , HPA035305: " "unprognostic (1.73e-2)" "unprognostic (2.01e-1)" "unprognostic (6.80e-2)" "unprognostic (1.18e-2)" "unprognostic (6.89e-2)" "unprognostic (5.27e-2)" "unprognostic (1.63e-1)" "unprognostic (1.78e-1)" "unprognostic (2.04e-3)" "unprognostic (2.90e-1)" "unprognostic (1.11e-3)" "potential prognostic favorable (3.24e-6)" "unprognostic (6.37e-2)" "unprognostic (8.26e-2)" "unprognostic (6.57e-3)" "unprognostic (7.91e-3)" "unprognostic (3.60e-2)" "unprognostic (1.82e-3)" "potential prognostic favorable (2.43e-5)" "unprognostic (3.77e-2)" "unprognostic (6.40e-2)" "unprognostic (1.10e-1)" "unprognostic (1.19e-1)" "unprognostic (5.32e-2)" "unprognostic (1.51e-1)" "unprognostic (7.53e-2)" "unprognostic (2.15e-1)" "unprognostic (1.80e-1)" "unprognostic (2.93e-1)" "unprognostic (1.46e-2)" "unprognostic (1.99e-1)" FGFR3 "ACH, CD333, CEK2, JTK4" ENSG00000068078 "Fibroblast growth factor receptor 3" P22607 4 1793293-1808872 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Apoptosis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Deafness, Disease variant, Dwarfism, Ectodermal dysplasia, FDA approved drug targets, Lacrimo-auriculo-dento-digital syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 148.8;esophagus: 126.6;skin 1: 256.5" "Cell type enhanced" "Detected in many" "Astrocytes: 527.6;Basal keratinocytes: 111.5;Bergmann glia: 251.5;Cholangiocytes: 105.9;Esophageal apical cells: 112.4;Esophageal suprabasal cells: 128.9;Ocular epithelial cells: 148.5;Pancreatic duct cells: 86.9;Prostatic hillock cells: 92.4;Proximal tubule cells: 123.8;Respiratory basal cells: 103.8;Suprabasal keratinocytes: 90.5" "Group enriched" "Detected in many" 6 "astrocyte: 516.1;Bergmann glia: 251.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 150.3" "Minor Salivary Gland - Minor salivary gland basal cells, Pituitary gland - Corticotropes, Prostate - Urothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004231, HPA067204" Enhanced Supported "Endoplasmic reticulum" "Secreted - unknown location" Receptor NA NA 500000 "Cluster 2: Non-specific - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 28: Astrocytes - Homeostasis & neuron support" 218 "Endoplasmic reticulum" "CAB004231: , HPA067204: " "unprognostic (7.73e-2)" "unprognostic (2.30e-1)" "unprognostic (1.05e-1)" "unprognostic (2.81e-2)" "unprognostic (8.61e-2)" "potential prognostic favorable (6.13e-6)" "unprognostic (1.48e-1)" "unprognostic (2.38e-3)" "unprognostic (2.46e-2)" "potential prognostic favorable (2.62e-4)" "unprognostic (1.54e-3)" "unprognostic (1.17e-1)" "unprognostic (9.96e-2)" "unprognostic (3.69e-1)" "unprognostic (1.30e-1)" "unprognostic (8.95e-3)" "unprognostic (5.08e-2)" "unprognostic (2.92e-1)" "unprognostic (2.59e-1)" "unprognostic (5.81e-2)" "unprognostic (1.92e-1)" "unprognostic (9.33e-3)" "unprognostic (3.15e-2)" "unprognostic (8.71e-2)" "unprognostic (5.51e-2)" "unprognostic (3.73e-1)" "unprognostic (3.05e-2)" "unprognostic (1.57e-1)" "unprognostic (3.47e-2)" "unprognostic (5.02e-2)" FGFR4 "CD334, JTK2" ENSG00000160867 "Fibroblast growth factor receptor 4" P22455 5 177086905-177098144 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 81.5;lung: 62.9" "Cell type enhanced" "Detected in many" "Cholangiocytes: 96.0;Enteric stem cells: 42.7;Enteric transient amplifying cells: 38.1;Hepatocytes: 30.3;Myosatellite cells: 106.9;Pancreatic duct cells: 47.3;Paneth cells: 38.7;Podocytes: 43.1;Proximal tubule cells: 40.7;Tuft cells: 149.9" "Cell type enriched" "Detected in some" 7 "fibroblast: 21.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "liver cancer: 117.0" "Breast - Breast glandular cells, Liver - Hepatocytes, Lung - Fibroblasts_1, Prostate - Fibroblasts, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB005196, HPA027273, HPA027369, HPA028251" Approved "Intracellular and membrane" Receptor NA NA 1900000 "Cluster 77: Intestine - Digestion" "Cluster 15: Non-specific - Transcription" "Cluster 18: Liver cancer - Metabolism" "Cluster 95: Tuft cells - Chemosensory signaling" 28 "CAB005196: , HPA027273: , HPA027369: , HPA028251: " "unprognostic (8.24e-3)" "unprognostic (6.16e-2)" "unprognostic (3.94e-2)" "unprognostic (2.00e-3)" "unprognostic (9.33e-2)" "unprognostic (1.08e-1)" "unprognostic (2.22e-1)" "unprognostic (3.24e-3)" "unprognostic (8.63e-3)" "unprognostic (1.06e-1)" "unprognostic (2.60e-1)" "unprognostic (5.41e-2)" "unprognostic (1.10e-2)" "unprognostic (4.14e-2)" "unprognostic (2.42e-1)" "unprognostic (4.41e-2)" "unprognostic (4.76e-2)" "unprognostic (4.39e-2)" "unprognostic (1.28e-1)" "unprognostic (2.12e-1)" "unprognostic (5.98e-2)" "unprognostic (1.60e-2)" "unprognostic (2.47e-2)" "unprognostic (1.24e-1)" "unprognostic (2.98e-2)" "unprognostic (1.64e-1)" "unprognostic (1.08e-2)" "unprognostic (1.54e-1)" "unprognostic (4.13e-1)" FGFRL1 ENSG00000127418 "Fibroblast growth factor receptor like 1" Q8N441 4 1009936-1026898 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 41.9;Hepatocytes: 40.4;Müller glia: 95.9;Retinal pigment epithelial cells: 42.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.1;non-classical monocyte: 1.2" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Pituitary gland - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026019, HPA068828" Approved Supported Vesicles No No "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 70: Non-specific - Protein processing" "Cluster 19: Astrocytes - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 11: Muller glia cells - Retinal homeostasis" 10 Vesicles "CAB026019: , HPA068828: " "unprognostic (2.47e-2)" "unprognostic (7.03e-2)" "unprognostic (2.88e-3)" "unprognostic (1.60e-3)" "unprognostic (3.62e-1)" "unprognostic (1.85e-1)" "unprognostic (4.16e-2)" "potential prognostic unfavorable (5.87e-4)" "unprognostic (3.01e-1)" "unprognostic (1.56e-1)" "unprognostic (1.62e-2)" "unprognostic (1.18e-1)" "unprognostic (8.37e-3)" "unprognostic (2.28e-2)" "unprognostic (2.32e-1)" "unprognostic (2.30e-2)" "unprognostic (1.94e-1)" "unprognostic (5.94e-2)" "unprognostic (1.66e-1)" "unprognostic (2.57e-1)" "unprognostic (6.24e-2)" "unprognostic (2.49e-3)" "unprognostic (1.02e-1)" "unprognostic (6.43e-2)" "unprognostic (7.87e-2)" "unprognostic (5.13e-2)" "unprognostic (3.82e-2)" "unprognostic (6.72e-2)" "unprognostic (3.83e-2)" "unprognostic (6.45e-2)" "unprognostic (5.04e-3)" FGG ENSG00000171557 "Fibrinogen gamma chain" P02679 4 154604134-154612967 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 327 "liver: 15475.1" "Cell type enriched" "Detected in some" 13 "Hepatocytes: 8736.4" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 9 "Liver Hepatocellular Carcinoma (TCGA): 4055.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "liver cancer: 229.6" "Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA011159, HPA027529, CAB033120, HPA074638" Supported Approved "Endoplasmic reticulum,Vesicles" "Secreted to blood" "Blood coagulation" NA NA 267000000000 130000000000 "Cluster 53: Liver - Plasma proteins" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 6 "Endoplasmic reticulum" Vesicles "CAB033120: , HPA011159: , HPA027529: , HPA074638: " "unprognostic (2.72e-2)" "unprognostic (3.50e-2)" "unprognostic (2.97e-1)" "unprognostic (6.99e-2)" "unprognostic (6.67e-2)" "unprognostic (4.64e-3)" "unprognostic (9.60e-2)" "unprognostic (5.43e-3)" "unprognostic (2.77e-2)" "unprognostic (3.65e-2)" "unprognostic (3.67e-1)" "potential prognostic unfavorable (1.24e-4)" "unprognostic (2.58e-1)" "unprognostic (8.80e-3)" "potential prognostic unfavorable (3.59e-5)" "unprognostic (3.39e-3)" "unprognostic (3.28e-1)" FGGY FLJ10986 ENSG00000172456 "FGGY carbohydrate kinase domain containing" Q96C11 1 59296638-59810647 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Amyotrophic lateral sclerosis, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 70.7" "Cell type enhanced" "Detected in many" "Cholangiocytes: 495.6;Myonuclei: 526.5;Proximal tubule cells: 778.6;Thymic myoid cells: 806.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 99.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054971, HPA075137" Approved "Nucleoplasm,Nuclear bodies" NA NA 95000 "Cluster 14: Non-specific - Unknown function" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 25: Non-specific - Transcription" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 2 Nucleoplasm "Nuclear bodies" "HPA054971: , HPA075137: " "unprognostic (3.84e-1)" "unprognostic (8.80e-2)" "unprognostic (2.44e-1)" "unprognostic (2.17e-1)" "unprognostic (3.91e-1)" "unprognostic (9.12e-2)" "unprognostic (1.48e-1)" "unprognostic (1.92e-1)" "unprognostic (3.73e-3)" "unprognostic (2.96e-1)" "validated prognostic favorable (2.00e-6)" "validated prognostic favorable (2.57e-4)" "potential prognostic favorable (2.17e-4)" "unprognostic (1.63e-3)" "potential prognostic favorable (5.33e-4)" "unprognostic (1.75e-1)" "unprognostic (1.57e-1)" "unprognostic (1.57e-1)" "unprognostic (1.64e-2)" "unprognostic (3.44e-1)" "unprognostic (8.68e-2)" "unprognostic (1.92e-1)" "unprognostic (2.07e-1)" "unprognostic (1.46e-1)" "unprognostic (2.59e-1)" "unprognostic (6.07e-2)" "unprognostic (4.17e-1)" "unprognostic (9.15e-2)" "unprognostic (1.72e-1)" "unprognostic (1.62e-1)" "unprognostic (1.49e-1)" FGL1 "HFREP-1, HPS" ENSG00000104760 "Fibrinogen like 1" Q08830 8 17864380-17910365 "Plasma proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 3863.2" "Cell type enriched" "Detected in some" 12 "Hepatocytes: 7991.4" "Cell type enriched" "Detected in some" 8 "central nervous system macrophage: 165.9" "Cancer enriched" "Detected in many" 20 "Liver Hepatocellular Carcinoma (TCGA): 1379.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Gastric cancer: 14.9;liver cancer: 57.2" "Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted to blood" Immunity NA NA 33700000 250000000 "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 53: Neurons - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 3 "unprognostic (2.03e-1)" "unprognostic (2.72e-2)" "unprognostic (2.98e-1)" "unprognostic (9.82e-2)" "potential prognostic unfavorable (1.86e-4)" "unprognostic (1.85e-1)" "unprognostic (3.52e-1)" "unprognostic (2.31e-1)" "unprognostic (3.15e-1)" "unprognostic (3.81e-2)" "unprognostic (3.12e-1)" "unprognostic (1.03e-3)" "unprognostic (4.06e-3)" "unprognostic (2.71e-2)" "potential prognostic unfavorable (3.04e-4)" "unprognostic (4.66e-2)" FGL2 "pT49, T49" ENSG00000127951 "Fibrinogen like 2" Q14314 7 77193369-77199848 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 153.8;lymphoid tissue: 153.1" "Cell type enhanced" "Detected in many" "cDC: 535.7;Kupffer cells: 591.4;Lymphatic endothelial cells: 136.1;Macrophages: 448.4;Monocyte progenitors: 139.9;monocytes: 590.4;Neutrophils: 116.8;Schwann cells: 614.1" "Group enriched" "Detected in many" 9 "central nervous system macrophage: 130.6;fibroblast: 105.0;leukocyte: 48.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 45 "classical monocyte: 256.3;eosinophil: 226.5;intermediate monocyte: 380.2;myeloid DC: 159.9;neutrophil: 295.2;non-classical monocyte: 381.5" "Group enriched" "Detected in all" 59 "dendritic cells: 159.9;granulocytes: 295.2;monocytes: 381.5" "Group enriched" "Detected in some" 5 "breast cancer: 9.9;Leukemia: 3.5;skin cancer: 13.7" "Minor Salivary Gland - Fibroblasts, Skeletal muscle - Fibroblasts, Spleen - Macrophages, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021011, HPA026682" Enhanced "Secreted to blood" "No annotated function" NA NA 38800000 17000000 "Cluster 7: Non-specific - Innate immune response" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 25: Non-specific - Transcription" "Cluster 70: DU4475 - Unknown function" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 2 "HPA021011: , HPA026682: " "unprognostic (4.02e-3)" "unprognostic (4.22e-2)" "unprognostic (1.48e-1)" "unprognostic (3.36e-2)" "unprognostic (2.55e-1)" "unprognostic (3.16e-1)" "unprognostic (2.89e-1)" "unprognostic (3.97e-1)" "unprognostic (2.64e-2)" "unprognostic (1.23e-1)" "potential prognostic favorable (2.00e-6)" "unprognostic (8.02e-2)" "unprognostic (4.20e-2)" "unprognostic (1.02e-1)" "unprognostic (2.76e-2)" "potential prognostic favorable (4.01e-4)" "unprognostic (6.57e-2)" "unprognostic (2.25e-1)" "unprognostic (4.91e-1)" "unprognostic (3.10e-1)" "unprognostic (6.14e-2)" "unprognostic (1.80e-1)" "unprognostic (2.54e-1)" "unprognostic (2.44e-1)" "unprognostic (2.16e-2)" "unprognostic (1.66e-1)" "unprognostic (2.44e-1)" "unprognostic (3.05e-2)" "unprognostic (1.83e-2)" "unprognostic (1.08e-1)" "unprognostic (7.33e-2)" FGR "c-fgr, p55c-fgr, SRC2" ENSG00000000938 "FGR proto-oncogene, Src family tyrosine kinase" P09769 1 27612064-27635185 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Immunity, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 196.5;lung: 83.0;lymphoid tissue: 136.4" "Cell type enhanced" "Detected in some" "cDC: 133.3;Kupffer cells: 134.3;Macrophages: 103.3;Monocyte progenitors: 215.0;monocytes: 408.3;Neutrophil progenitors: 307.3;Neutrophils: 909.6;NK-cells: 84.3" "Group enriched" "Detected in some" 12 "endothelial cell: 71.5;leukocyte: 85.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 16 "Leukemia: 21.4;lymphoma: 33.4;Myeloma: 17.9" "Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophils_2, Spleen - Neutrophils_2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA002024 Enhanced Approved "Plasma membrane,Aggresome" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 55: Lymphoma - Immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 16 "Plasma membrane" Aggresome "HPA002024: " "unprognostic (3.09e-3)" "unprognostic (1.17e-2)" "potential prognostic favorable (1.06e-5)" "unprognostic (5.32e-2)" "unprognostic (2.40e-1)" "unprognostic (3.70e-2)" "unprognostic (3.00e-3)" "unprognostic (8.03e-2)" "unprognostic (6.93e-2)" "unprognostic (1.38e-1)" "unprognostic (1.95e-2)" "unprognostic (2.77e-1)" "unprognostic (2.34e-2)" "unprognostic (1.13e-2)" "unprognostic (2.06e-1)" "unprognostic (2.49e-2)" "unprognostic (1.88e-3)" "unprognostic (9.14e-2)" "unprognostic (3.13e-1)" "unprognostic (7.58e-2)" "unprognostic (1.29e-1)" "unprognostic (1.89e-2)" "unprognostic (4.87e-3)" "unprognostic (3.57e-2)" "potential prognostic unfavorable (7.38e-4)" "unprognostic (1.86e-3)" "unprognostic (1.20e-1)" "unprognostic (6.16e-2)" "unprognostic (2.30e-2)" "unprognostic (2.26e-1)" "unprognostic (9.55e-2)" FH ENSG00000091483 "Fumarate hydratase" P07954 1 241497511-241519799 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Tricarboxylic acid cycle" Lyase "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 252.7" "Cell type enhanced" "Detected in all" "Early spermatids: 196.9;Late primary spermatocytes: 207.8;Syncytiotrophoblasts: 199.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017785, HPA025770, HPA025948, HPA027341, CAB080323" Enhanced Supported Supported Mitochondria NA NA 2300000 "Cluster 13: Non-specific - Mitochondria" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 45: Non-specific - Nuclear processes" "Cluster 97: Non-specific - Cellular respiration" 20 Mitochondria "CAB017785: , CAB080323: , HPA025770: , HPA025948: , HPA027341: " "unprognostic (1.03e-3)" "unprognostic (2.22e-3)" "unprognostic (7.07e-2)" "potential prognostic favorable (4.63e-4)" "unprognostic (1.87e-3)" "unprognostic (1.65e-1)" "unprognostic (5.22e-2)" "unprognostic (8.32e-2)" "unprognostic (1.18e-1)" "potential prognostic unfavorable (8.42e-4)" "potential prognostic favorable (2.05e-5)" "unprognostic (3.30e-2)" "potential prognostic favorable (2.52e-6)" "unprognostic (1.07e-1)" "unprognostic (2.48e-2)" "unprognostic (2.86e-2)" "unprognostic (1.51e-1)" "unprognostic (3.14e-1)" "unprognostic (2.62e-1)" "unprognostic (5.49e-3)" "unprognostic (2.83e-1)" "unprognostic (3.04e-2)" "unprognostic (5.01e-2)" "unprognostic (3.13e-1)" "unprognostic (2.95e-1)" "unprognostic (1.23e-1)" "unprognostic (1.89e-1)" "unprognostic (1.14e-1)" "unprognostic (1.35e-1)" "unprognostic (1.99e-2)" "unprognostic (6.45e-2)" FHAD1 KIAA1937 ENSG00000142621 "Forkhead associated phosphopeptide binding domain 1" B1AJZ9 1 15236521-15400283 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 9.9;fallopian tube: 14.6;testis: 12.5" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 158.6;Early spermatids: 449.8;Endometrial ciliated cells: 459.5;Ependymal cells: 463.6;Epididymal efferent duct ciliated cells: 417.2;Fallopian tube ciliated cells: 335.5;Late primary spermatocytes: 155.8;Late spermatids: 616.3;Respiratory ciliated cells: 681.4" "Cell type enriched" "Detected in many" 4 "ependymal cell: 472.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA054284 Enhanced Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 49: HMC-1 - Innate immune response" "Cluster 107: Ciliated cells - Cilia assembly & function" "Nucleoplasm, Nuclear bodies" "HPA054284: " "unprognostic (3.78e-2)" "unprognostic (6.90e-2)" "unprognostic (1.68e-1)" "unprognostic (2.67e-3)" "unprognostic (1.68e-1)" "unprognostic (8.59e-2)" "unprognostic (3.24e-3)" "unprognostic (8.24e-2)" "unprognostic (1.25e-2)" "unprognostic (9.78e-2)" "unprognostic (4.13e-2)" "unprognostic (3.05e-2)" "unprognostic (4.72e-2)" "unprognostic (4.92e-2)" "unprognostic (1.01e-1)" "unprognostic (3.36e-3)" "unprognostic (1.00e-1)" "unprognostic (2.63e-2)" "unprognostic (5.88e-3)" "unprognostic (1.66e-1)" "unprognostic (1.60e-1)" "unprognostic (1.02e-2)" "unprognostic (9.48e-2)" "unprognostic (1.17e-1)" FHDC1 "INF1, KIAA1727" ENSG00000137460 "FH2 domain containing 1" Q9C0D6 4 152936323-152979671 "Predicted intracellular proteins" "Cilium biogenesis/degradation" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 16.5;thyroid gland: 14.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 110.6;Prostatic glandular cells: 54.8;Syncytiotrophoblasts: 196.3" "Cell type enhanced" "Detected in many" "medium spiny neuron: 39.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008527, HPA008603" Uncertain Uncertain "Primary cilium,Centrosome,Basal body" NA NA "Cluster 69: Parathyroid gland - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" "Centrosome, Basal body" "Primary cilium" "HPA008527: , HPA008603: " "unprognostic (8.66e-2)" "unprognostic (3.64e-2)" "unprognostic (3.23e-1)" "unprognostic (1.52e-1)" "unprognostic (1.41e-2)" "unprognostic (5.13e-2)" "unprognostic (1.14e-1)" "potential prognostic favorable (3.06e-4)" "unprognostic (2.63e-1)" "unprognostic (2.10e-1)" "unprognostic (1.94e-1)" "unprognostic (6.97e-2)" "unprognostic (1.09e-2)" "unprognostic (3.96e-2)" "unprognostic (1.20e-1)" "unprognostic (1.68e-1)" "unprognostic (1.93e-1)" "unprognostic (3.36e-1)" "unprognostic (8.07e-3)" "unprognostic (2.22e-2)" "unprognostic (6.18e-2)" "unprognostic (1.64e-1)" "unprognostic (3.69e-2)" "unprognostic (5.35e-2)" "unprognostic (2.20e-1)" "unprognostic (1.75e-1)" "unprognostic (2.75e-1)" "unprognostic (5.89e-2)" "unprognostic (1.10e-1)" FHIP1A "FAM160A1, FHIP-L, FLJ43373" ENSG00000164142 "FHF complex subunit HOOK interacting protein 1A" Q05DH4 4 151409176-151670503 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 32.3" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 988.9;Endometrial glandular cells: 1217.4;Endometrial luminal cells: 999.8;Endometrial secretory cells: 884.8;Myonuclei: 1072.0;Salivary basal cells: 1230.6;Urothelial cells: 932.9" "Cell type enriched" "Detected in many" 4 "choroid plexus epithelial cell: 863.0" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in all" 12 "cerebellum: 29.3;choroid plexus: 68.6" "Immune cell enriched" "Detected in single" 14 "plasmacytoid DC: 2.5" "Lineage enriched" "Detected in single" 14 "dendritic cells: 2.5" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Prostate - Prostate basal glandular cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA046348 Enhanced Approved Cytosol NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 5: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 51: Secretory epithelial cells - Mixed function" 7 Cytosol "HPA046348: " "unprognostic (2.76e-1)" "unprognostic (7.12e-2)" "unprognostic (1.10e-1)" "unprognostic (7.83e-3)" "unprognostic (3.22e-2)" "unprognostic (2.61e-1)" "potential prognostic unfavorable (3.51e-4)" "unprognostic (8.85e-2)" "unprognostic (3.95e-2)" "validated prognostic favorable (1.38e-11)" "validated prognostic favorable (6.20e-7)" "unprognostic (3.18e-2)" "unprognostic (2.93e-1)" "unprognostic (7.08e-2)" "unprognostic (1.04e-1)" "unprognostic (4.16e-1)" "unprognostic (5.06e-3)" "unprognostic (4.45e-2)" "unprognostic (3.64e-3)" "unprognostic (4.65e-3)" "unprognostic (7.72e-2)" "unprognostic (5.77e-2)" "unprognostic (1.53e-1)" "unprognostic (4.98e-2)" "unprognostic (1.67e-1)" "unprognostic (7.58e-2)" "unprognostic (9.20e-2)" FHIP1B "C11orf56, DKFZP566M1046, FAM160A2, FHIP, FLJ22665, KIAA1759" ENSG00000051009 "FHF complex subunit HOOK interacting protein 1B" Q8N612 11 6211345-6234711 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 138.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055994, HPA063987" Approved Approved Mitochondria NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 12 Mitochondria "HPA055994: , HPA063987: " "unprognostic (4.47e-2)" "unprognostic (3.28e-1)" "unprognostic (8.76e-3)" "potential prognostic unfavorable (9.62e-4)" "unprognostic (2.93e-1)" "unprognostic (1.98e-3)" "unprognostic (5.68e-2)" "unprognostic (2.02e-1)" "unprognostic (3.08e-1)" "unprognostic (1.52e-1)" "potential prognostic favorable (5.28e-6)" "unprognostic (1.25e-2)" "unprognostic (4.70e-3)" "unprognostic (9.26e-2)" "unprognostic (2.43e-2)" "unprognostic (1.24e-1)" "unprognostic (1.03e-1)" "unprognostic (2.12e-2)" "unprognostic (1.47e-2)" "unprognostic (4.47e-2)" "unprognostic (8.44e-2)" "unprognostic (6.80e-2)" "unprognostic (1.34e-1)" "unprognostic (2.82e-1)" "unprognostic (1.74e-3)" "unprognostic (1.61e-1)" "unprognostic (1.13e-1)" "unprognostic (3.33e-1)" "unprognostic (2.80e-1)" "unprognostic (1.53e-1)" "unprognostic (1.32e-2)" FHIP2A "bA106M7.3, FAM160B1, KIAA1600" ENSG00000151553 "FHF complex subunit HOOK interacting protein 2A" Q5W0V3 10 114821744-114899832 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 50.3" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 141.6;Neutrophils: 160.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043624 Uncertain Approved "Nuclear speckles,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 7 "Nuclear speckles" Cytosol "HPA043624: " "unprognostic (2.79e-3)" "unprognostic (2.41e-2)" "unprognostic (6.13e-2)" "unprognostic (8.00e-2)" "unprognostic (1.32e-1)" "unprognostic (5.87e-2)" "unprognostic (2.27e-1)" "unprognostic (5.10e-3)" "unprognostic (2.42e-2)" "unprognostic (1.99e-1)" "unprognostic (1.79e-2)" "unprognostic (8.78e-2)" "unprognostic (3.55e-1)" "unprognostic (6.32e-2)" "unprognostic (1.78e-3)" "unprognostic (2.32e-1)" "unprognostic (2.76e-1)" "unprognostic (2.93e-1)" "unprognostic (2.91e-2)" "unprognostic (1.46e-1)" "potential prognostic unfavorable (1.99e-4)" "unprognostic (3.58e-1)" "unprognostic (2.02e-1)" "unprognostic (1.72e-1)" "unprognostic (2.75e-1)" "unprognostic (6.48e-3)" "unprognostic (3.05e-1)" "unprognostic (1.54e-2)" "unprognostic (1.06e-1)" "unprognostic (4.71e-2)" "unprognostic (1.99e-1)" FHIP2B "FAM160B2, FLJ21801, RAI16" ENSG00000158863 "FHF complex subunit HOOK interacting protein 2B" Q86V87 8 22089150-22104911 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025040 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 24: Non-specific - Transcription" "Cluster 18: Non-specific - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 4: Breast lactating luminal cells - Lactation" 3 Nucleoplasm Cytosol "HPA025040: " "unprognostic (7.78e-2)" "unprognostic (2.49e-1)" "potential prognostic favorable (1.01e-4)" "unprognostic (2.68e-2)" "unprognostic (1.50e-1)" "unprognostic (5.67e-2)" "unprognostic (8.24e-2)" "unprognostic (2.21e-2)" "unprognostic (4.29e-3)" "unprognostic (4.14e-1)" "unprognostic (5.34e-2)" "unprognostic (1.26e-1)" "unprognostic (1.72e-2)" "unprognostic (1.33e-1)" "unprognostic (3.11e-2)" "unprognostic (2.66e-1)" "unprognostic (1.52e-1)" "unprognostic (1.07e-1)" "unprognostic (1.85e-1)" "unprognostic (2.73e-2)" "unprognostic (2.26e-1)" "unprognostic (1.52e-2)" "unprognostic (7.34e-2)" "unprognostic (8.10e-2)" "unprognostic (2.79e-1)" "unprognostic (2.48e-1)" "unprognostic (5.34e-2)" "unprognostic (3.27e-2)" "unprognostic (4.13e-1)" "unprognostic (8.20e-2)" "unprognostic (6.83e-2)" FHIT "AP3Aase, FRA3B" ENSG00000189283 "Fragile histidine triad diadenosine triphosphatase" P49789 3 59747277-61251459 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" "Hydrolase, Transferase" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 25 "choroid plexus: 607.4" "Cell type enhanced" "Detected in all" "Adrenal cortex cells: 2246.1;Distal convoluted tubule cells: 2769.7;Proximal tubule cells: 2734.2;Retinal pigment epithelial cells: 2591.9;Sertoli cells: 2162.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "choroid plexus: 194.5" "Immune cell enriched" "Detected in many" 4 "naive CD4 T-cell: 87.9" "Lineage enriched" "Detected in all" 12 "T-cells: 87.9" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002684, HPA018840, HPA018909" Enhanced Approved "Nucleoli fibrillar center,Plasma membrane" NA NA 9200 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" 8 "Nucleoli fibrillar center, Plasma membrane" "CAB002684: , HPA018840: , HPA018909: " "unprognostic (9.19e-3)" "unprognostic (6.16e-3)" "unprognostic (2.41e-1)" "unprognostic (7.50e-2)" "unprognostic (3.58e-2)" "unprognostic (2.96e-2)" "unprognostic (4.14e-2)" "unprognostic (1.65e-2)" "unprognostic (5.13e-3)" "unprognostic (4.10e-3)" "potential prognostic favorable (5.95e-4)" "unprognostic (5.19e-3)" "potential prognostic favorable (3.81e-4)" "unprognostic (1.11e-1)" "unprognostic (2.02e-1)" "unprognostic (2.77e-2)" "unprognostic (3.79e-1)" "potential prognostic unfavorable (1.97e-4)" "unprognostic (6.23e-2)" "unprognostic (1.02e-1)" "unprognostic (3.66e-2)" "unprognostic (2.37e-1)" "unprognostic (8.83e-2)" "unprognostic (4.77e-2)" "unprognostic (6.77e-2)" "unprognostic (8.31e-2)" "unprognostic (1.20e-3)" "unprognostic (3.32e-2)" "unprognostic (8.54e-2)" "unprognostic (4.43e-3)" "unprognostic (1.85e-1)" FHL1 "bA535K18.1, FHL1B, FLH1A, KYO-T, MGC111107, SLIM1, XMPMA" ENSG00000022267 "Four and a half LIM domains 1" Q13642 X 136146702-136211359 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Differentiation "Developmental protein" "Disease variant, Emery-Dreifuss muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "skeletal muscle: 10741.5;tongue: 9124.0" "Cell type enhanced" "Detected in many" "Adipocytes: 294.0;Early spermatids: 439.1;Hepatic stellate cells: 367.9;Late spermatids: 1746.7;Myonuclei: 1299.3;Smooth muscle cells: 799.0;Thymic myoid cells: 909.6;Vascular smooth muscle cells: 434.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Renal Papillary Cell Carcinoma (TCGA): 624.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 36.3" "Group enriched" "Detected in many" 4 "dendritic cells: 19.5;NK-cells: 36.3;T-cells: 18.3" "Low cancer specificity" "Detected in all" "Liver - Hepatic stellate cells, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001040, HPA001391, CAB020817" Enhanced Uncertain "Plasma membrane,Cytosol" NA NA 11000000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 14: Neurons - Synaptic function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 34 Cytosol "Plasma membrane" "CAB020817: , HPA001040: , HPA001391: " "unprognostic (1.10e-1)" "unprognostic (2.90e-2)" "unprognostic (2.95e-1)" "unprognostic (5.24e-2)" "unprognostic (4.82e-2)" "unprognostic (1.32e-1)" "unprognostic (5.71e-2)" "unprognostic (7.24e-3)" "unprognostic (1.96e-2)" "unprognostic (1.45e-2)" "potential prognostic favorable (2.27e-4)" "unprognostic (7.78e-2)" "potential prognostic favorable (8.31e-4)" "unprognostic (1.51e-1)" "potential prognostic favorable (9.08e-4)" "unprognostic (2.66e-3)" "unprognostic (4.81e-2)" "unprognostic (1.33e-2)" "unprognostic (2.55e-1)" "unprognostic (1.25e-1)" "unprognostic (8.39e-2)" "unprognostic (1.58e-3)" "unprognostic (9.11e-2)" "unprognostic (2.52e-1)" "unprognostic (1.96e-2)" "unprognostic (7.69e-2)" "unprognostic (4.69e-2)" "unprognostic (3.01e-3)" "unprognostic (1.57e-1)" "unprognostic (2.79e-3)" "unprognostic (4.02e-2)" FHL2 "DRAL, SLIM3" ENSG00000115641 "Four and a half LIM domains 2" Q14192 2 105357712-105438513 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "heart muscle: 1337.6;ovary: 513.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 3363.2;Epididymal efferent duct ciliated cells: 632.9;Extravillous trophoblasts: 1005.1;Leydig cells: 746.3;Migrating cytotrophoblasts: 601.0;Ovarian stromal cells: 1038.6;Peritubular myoid cells: 1236.9" "Cell type enhanced" "Detected in many" "fibroblast: 320.3;hippocampal dentate gyrus: 118.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 5.1" "Group enriched" "Detected in many" 6 "granulocytes: 5.1;T-cells: 2.6" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Minor Salivary Gland - Endothelial cells, Pituitary gland - Fibroblasts, Spleen - Fibroblasts_1, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005922, HPA006028, CAB008368" Enhanced Enhanced "Actin filaments,Focal adhesion sites" NA Yes 4000 "Cluster 35: Neutrophils - Protein binding" "Cluster 35: Non-specific - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 193 "Actin filaments, Focal adhesion sites" "CAB008368: , HPA005922: , HPA006028: " "unprognostic (4.40e-2)" "unprognostic (7.57e-2)" "unprognostic (1.01e-1)" "unprognostic (8.08e-3)" "unprognostic (3.14e-1)" "unprognostic (8.15e-2)" "unprognostic (4.63e-2)" "unprognostic (4.30e-3)" "potential prognostic unfavorable (4.13e-5)" "unprognostic (7.89e-2)" "unprognostic (9.56e-3)" "unprognostic (5.77e-2)" "unprognostic (1.61e-1)" "unprognostic (6.61e-2)" "unprognostic (5.29e-3)" "unprognostic (4.77e-3)" "potential prognostic unfavorable (8.24e-6)" "unprognostic (1.70e-2)" "potential prognostic unfavorable (1.90e-4)" "unprognostic (1.62e-2)" "unprognostic (9.21e-2)" "unprognostic (1.25e-2)" "unprognostic (5.25e-2)" "unprognostic (2.77e-2)" "unprognostic (2.38e-1)" "unprognostic (3.13e-1)" "unprognostic (2.49e-1)" "unprognostic (8.03e-2)" "unprognostic (5.00e-2)" "unprognostic (1.87e-3)" "unprognostic (3.35e-1)" FHL3 SLIM2 ENSG00000183386 "Four and a half LIM domains 3" Q13643 1 37996770-38005606 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 27 "skeletal muscle: 1501.5;tongue: 752.0" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 56.8;Myonuclei: 379.1;Platelets: 62.0;Smooth muscle cells: 87.7;Thymic myoid cells: 174.0" "Cell type enhanced" "Detected in many" "endothelial cell: 42.8;fibroblast: 21.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 10 "eosinophil: 336.7" "Lineage enriched" "Detected in many" 12 "granulocytes: 336.7" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Pituitary gland - Endothelial cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA045723 Approved Nucleoplasm NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 47: Endothelial cells - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 156 Nucleoplasm "HPA045723: " "unprognostic (3.36e-2)" "unprognostic (2.58e-2)" "unprognostic (1.24e-1)" "unprognostic (3.84e-2)" "unprognostic (2.37e-2)" "unprognostic (8.26e-2)" "unprognostic (6.47e-2)" "unprognostic (9.76e-2)" "unprognostic (2.35e-2)" "unprognostic (3.71e-1)" "unprognostic (3.06e-2)" "unprognostic (8.09e-2)" "unprognostic (5.65e-3)" "potential prognostic unfavorable (5.20e-5)" "unprognostic (4.92e-2)" "validated prognostic unfavorable (8.06e-4)" "validated prognostic unfavorable (3.69e-7)" "unprognostic (2.81e-2)" "unprognostic (2.60e-1)" "unprognostic (5.90e-3)" "unprognostic (2.41e-1)" "unprognostic (1.56e-1)" "unprognostic (2.04e-2)" "unprognostic (1.26e-1)" "unprognostic (3.94e-2)" "unprognostic (1.93e-2)" "unprognostic (4.61e-1)" "unprognostic (9.28e-3)" "unprognostic (2.02e-1)" "unprognostic (1.90e-1)" "unprognostic (1.41e-1)" FHL5 "ACT, dJ393D12.2, FLJ33049" ENSG00000112214 "Four and a half LIM domains 5" Q5TD97 6 96562548-96618626 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "blood vessel: 244.7" "Group enriched" "Detected in some" 4 "Early spermatids: 1427.3;Late spermatids: 1946.7" "Group enriched" "Detected in some" 7 "pericyte: 419.1;vascular associated smooth muscle cell: 579.5" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 11.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Adrenal gland - Fibroblasts, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Smooth muscle cells, Prostate - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Smooth muscle cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 47: Endothelial cells - Vasculature" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 68 "unprognostic (3.53e-2)" "unprognostic (3.20e-2)" "unprognostic (1.13e-1)" "unprognostic (6.14e-2)" "unprognostic (4.81e-2)" "validated prognostic favorable (4.62e-7)" "validated prognostic favorable (1.64e-5)" "unprognostic (2.61e-2)" "unprognostic (9.37e-3)" "unprognostic (1.24e-1)" "unprognostic (1.64e-1)" "unprognostic (2.56e-1)" "unprognostic (6.86e-2)" "unprognostic (1.07e-1)" "unprognostic (1.55e-3)" "unprognostic (1.90e-1)" FHOD1 FHOS ENSG00000135723 "Formin homology 2 domain containing 1" Q9Y613 16 67229387-67247481 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 93.9;skeletal muscle: 119.0" "Cell type enhanced" "Detected in many" "Breast lactating cells: 66.4;Megakaryocytes: 74.2;Myonuclei: 69.9;Platelets: 40.9" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 27.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Pituitary gland - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA024468 Approved Supported Cytosol NA NA 640000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 12: Non-specific - Vasculature" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 110: Mural cells - ECM organization" 4 Cytosol "HPA024468: " "unprognostic (1.37e-3)" "unprognostic (1.78e-3)" "unprognostic (5.17e-3)" "unprognostic (7.30e-2)" "unprognostic (3.96e-2)" "unprognostic (2.25e-1)" "unprognostic (5.06e-2)" "unprognostic (2.70e-2)" "unprognostic (3.12e-2)" "unprognostic (1.79e-1)" "unprognostic (8.99e-2)" "unprognostic (6.67e-2)" "unprognostic (1.14e-1)" "unprognostic (1.33e-1)" "unprognostic (2.19e-2)" "unprognostic (1.16e-1)" "unprognostic (1.21e-2)" "unprognostic (7.66e-3)" "unprognostic (1.83e-1)" "unprognostic (1.64e-1)" "unprognostic (2.42e-2)" "unprognostic (2.32e-1)" "potential prognostic unfavorable (5.40e-4)" "unprognostic (8.23e-2)" "unprognostic (1.48e-1)" "unprognostic (1.20e-1)" "unprognostic (2.00e-1)" "unprognostic (2.28e-1)" "unprognostic (8.01e-2)" "unprognostic (3.16e-2)" "unprognostic (1.57e-1)" FHOD3 "FHOS2, FLJ22297, FLJ22717, KIAA1695" ENSG00000134775 "Formin homology 2 domain containing 3" Q2V2M9 18 36297713-36780220 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 143.4" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 517.4;Adrenal medulla cells: 436.1;Cardiomyocytes: 1181.2;Cone photoreceptor cells: 1144.8;Distal convoluted tubule cells: 1045.1;Gonadotrophs: 417.9;Myonuclei: 595.4;Proximal tubule cells: 788.3;Renal collecting duct principal cells: 410.9;Renal connecting tubule cells: 979.2;Retinal amacrine cells: 418.7;Rod photoreceptor cells: 468.1;Salivary myoepithelial cells: 626.7" "Cell type enhanced" "Detected in all" "lower rhombic lip: 920.2" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 40.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast myoepithelial cells, Heart muscle - Cardiomyocytes, Liver - Hepatic stellate cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - Smooth muscle cells, Pituitary gland - Somatotropes, Prostate - Smooth muscle cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021827, HPA024696" Uncertain NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 24: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 55: Myocytes - Oxidative muscle function" 6 "HPA021827: , HPA024696: " "unprognostic (8.42e-3)" "unprognostic (2.15e-1)" "unprognostic (4.21e-1)" "unprognostic (1.91e-1)" "unprognostic (9.46e-2)" "unprognostic (8.56e-2)" "unprognostic (1.55e-1)" "potential prognostic favorable (1.08e-4)" "unprognostic (2.10e-1)" "unprognostic (1.97e-1)" "unprognostic (3.17e-1)" "unprognostic (6.47e-2)" "unprognostic (1.30e-3)" "unprognostic (1.92e-3)" "unprognostic (5.83e-3)" "unprognostic (2.52e-3)" "unprognostic (3.01e-3)" "unprognostic (1.75e-1)" "unprognostic (9.22e-2)" "unprognostic (2.96e-2)" "unprognostic (2.20e-1)" "unprognostic (2.56e-3)" "unprognostic (3.71e-2)" "unprognostic (1.79e-1)" "unprognostic (2.17e-1)" "unprognostic (9.69e-2)" "unprognostic (1.38e-1)" "unprognostic (1.47e-2)" "unprognostic (5.69e-2)" "unprognostic (5.29e-3)" "unprognostic (2.26e-2)" FIBCD1 FLJ14810 ENSG00000130720 "Fibrinogen C domain containing 1" Q8N539 9 130902438-130939286 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "adrenal gland: 9.9;brain: 24.4;parathyroid gland: 11.8;testis: 6.4" "Cell type enhanced" "Detected in some" "Breast lactating cells: 9.2;Cytotrophoblasts: 16.1;Differentiating spermatogonia: 17.5;Early spermatids: 17.6;Enteric transient amplifying cells: 10.4;Epicardial cells: 11.4;Goblet cells: 16.3;Late primary spermatocytes: 26.3;Late spermatids: 66.0;Paneth cells: 11.6;Retinal amacrine cells: 30.4;Undifferentiated spermatogonia: 9.7" "Group enriched" "Detected in some" 5 "deep-layer corticothalamic and 6b: 8.3;hippocampal CA1-3: 18.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "hippocampal formation: 60.3" "Immune cell enriched" "Detected in single" 6 "non-classical monocyte: 1.1" "Lineage enriched" "Detected in single" 11 "monocytes: 1.1" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 43.7" "Testis - Sertoli cells" "Group enriched" "Detected in many" 4 "basal ganglia: 17.6;hippocampal formation: 68.5" "Region enriched" "Detected in many" 5 "hippocampal formation: 74.6" HPA055353 Approved Approved "Cell Junctions" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 29: Forebrain - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 3 "Cell Junctions" "HPA055353: " "unprognostic (1.30e-1)" "potential prognostic unfavorable (5.55e-4)" "unprognostic (2.53e-1)" "unprognostic (2.90e-2)" "unprognostic (1.38e-1)" "unprognostic (5.16e-2)" "unprognostic (7.38e-2)" "unprognostic (2.72e-2)" "unprognostic (1.09e-1)" "unprognostic (5.35e-2)" "unprognostic (1.41e-1)" "unprognostic (1.91e-2)" "potential prognostic unfavorable (1.92e-4)" "unprognostic (1.94e-1)" "unprognostic (9.85e-2)" "unprognostic (1.07e-2)" "unprognostic (3.24e-1)" "unprognostic (2.15e-1)" "unprognostic (1.50e-2)" "unprognostic (1.32e-1)" "unprognostic (1.32e-1)" "unprognostic (5.54e-2)" "unprognostic (4.79e-3)" FIBIN MGC24932 ENSG00000176971 "Fin bud initiation factor homolog" Q8TAL6 11 26994112-26997087 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 121.2" "Cell type enhanced" "Detected in some" "Astrocytes: 26.2;Bergmann glia: 21.9;Fibroblasts: 87.9;Hepatic stellate cells: 109.7;Leydig cells: 26.0;Medullary thymic epithelial cells: 24.0;Müller glia: 21.0;Oligodendrocyte progenitor cells: 38.4;Ovarian stromal cells: 33.2;Peritubular myoid cells: 37.4;Thymic myoid cells: 28.6;Vascular smooth muscle cells: 20.3" "Group enriched" "Detected in many" 4 "astrocyte: 28.8;Bergmann glia: 27.1;committed oligodendrocyte precursor: 84.2;oligodendrocyte precursor cell: 40.7" "Group enriched" "Detected in all" 4 "Glioblastoma Multiforme (TCGA): 56.0;Kidney Renal Papillary Cell Carcinoma (TCGA): 48.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 22 "Rhabdoid: 103.1" "Adrenal gland - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040120 Uncertain "Intracellular and membrane" "No annotated function" NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 108: Fibroblasts - ECM organization" 36 "HPA040120: " "potential prognostic favorable (4.08e-4)" "unprognostic (3.11e-1)" "unprognostic (8.68e-2)" "unprognostic (1.16e-1)" "unprognostic (8.53e-2)" "unprognostic (6.64e-2)" "unprognostic (3.20e-2)" "unprognostic (1.45e-1)" "unprognostic (2.36e-2)" "potential prognostic unfavorable (9.17e-4)" "potential prognostic favorable (1.99e-5)" "unprognostic (8.88e-2)" "potential prognostic favorable (1.55e-4)" "unprognostic (1.29e-1)" "unprognostic (1.10e-2)" "unprognostic (1.55e-1)" "unprognostic (1.33e-2)" "unprognostic (1.96e-1)" "unprognostic (4.18e-2)" "potential prognostic unfavorable (8.10e-4)" "unprognostic (1.74e-3)" "unprognostic (7.32e-2)" "unprognostic (3.84e-3)" "unprognostic (2.32e-1)" "unprognostic (3.20e-2)" "unprognostic (1.46e-2)" "unprognostic (6.68e-2)" "potential prognostic unfavorable (5.50e-4)" "unprognostic (8.60e-2)" "potential prognostic unfavorable (1.85e-5)" "unprognostic (1.76e-1)" FIBP FGFIBP ENSG00000172500 "FGF1 intracellular binding protein" O43427 11 65883740-65888531 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Late spermatids: 1043.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011729 Approved Supported "Nuclear speckles" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 24: Non-specific - Unknown function" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 5 "Nuclear speckles" "HPA011729: " "unprognostic (3.19e-3)" "unprognostic (3.31e-1)" "unprognostic (5.10e-2)" "unprognostic (2.82e-3)" "unprognostic (1.92e-1)" "unprognostic (3.20e-1)" "unprognostic (4.94e-1)" "unprognostic (1.74e-1)" "unprognostic (4.72e-2)" "unprognostic (3.58e-2)" "potential prognostic favorable (2.08e-4)" "unprognostic (1.11e-3)" "unprognostic (3.12e-2)" "potential prognostic unfavorable (7.50e-4)" "unprognostic (7.84e-3)" "unprognostic (1.40e-2)" "potential prognostic unfavorable (1.06e-5)" "unprognostic (2.15e-1)" "unprognostic (2.29e-1)" "unprognostic (1.73e-2)" "unprognostic (1.45e-1)" "unprognostic (5.48e-2)" "unprognostic (2.11e-1)" "unprognostic (8.17e-2)" "unprognostic (6.95e-2)" "unprognostic (2.05e-1)" "unprognostic (2.00e-1)" "unprognostic (1.04e-1)" "unprognostic (1.06e-1)" "unprognostic (4.50e-2)" "unprognostic (1.07e-1)" FICD "HIP13, HYPE" ENSG00000198855 "FIC domain protein adenylyltransferase" Q9BVA6 12 108515277-108525837 "Enzymes, Predicted intracellular proteins" "Unfolded protein response" "Hydrolase, Nucleotidyltransferase, Transferase" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 87.7;Epididymal principal cells: 56.8;Late spermatids: 76.4;Plasma cells: 45.1;Retinal pigment epithelial cells: 72.5;Syncytiotrophoblasts: 46.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021390, HPA071134" Approved Approved Nucleoplasm "Intracellular and membrane" Enzyme NA NA "Cluster 41: Basophils - Unknown function" "Cluster 22: Epididymis - Mixed function" "Cluster 27: Non-specific - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 8: Non-specific - Secretory pathway" 3 Nucleoplasm "HPA021390: , HPA071134: " "unprognostic (6.17e-2)" "unprognostic (2.20e-2)" "unprognostic (7.78e-2)" "unprognostic (1.49e-1)" "unprognostic (2.84e-1)" "unprognostic (2.86e-1)" "unprognostic (1.85e-1)" "unprognostic (4.03e-1)" "unprognostic (1.36e-2)" "unprognostic (1.14e-1)" "unprognostic (7.93e-2)" "unprognostic (1.72e-2)" "unprognostic (1.68e-1)" "unprognostic (4.87e-2)" "unprognostic (4.49e-1)" "unprognostic (1.60e-2)" "unprognostic (1.02e-1)" "unprognostic (2.27e-3)" "unprognostic (9.56e-2)" "unprognostic (2.05e-1)" "unprognostic (2.93e-2)" "unprognostic (3.82e-2)" "potential prognostic favorable (4.54e-4)" "unprognostic (2.12e-1)" "unprognostic (1.21e-2)" "unprognostic (3.82e-2)" "unprognostic (1.54e-1)" "unprognostic (3.45e-1)" "unprognostic (1.07e-1)" "unprognostic (1.81e-2)" "unprognostic (1.29e-1)" FIG4 "ALS11, CMT4J, dJ249I4.1, hSac3, KIAA0274, SAC3" ENSG00000112367 "FIG4 phosphoinositide 5-phosphatase" Q92562 6 109690609-109878098 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Amyotrophic lateral sclerosis, Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 119.3;Neutrophil progenitors: 150.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017823, HPA068859" Approved Supported "Vesicles,Lipid droplets" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 61: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 28: Non-specific - Nuclear processes" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 11 "Vesicles, Lipid droplets" "CAB017823: , HPA068859: " "unprognostic (2.98e-1)" "potential prognostic unfavorable (3.43e-4)" "unprognostic (1.07e-2)" "unprognostic (1.80e-2)" "unprognostic (2.89e-2)" "unprognostic (3.20e-1)" "unprognostic (6.84e-2)" "unprognostic (1.33e-2)" "unprognostic (7.91e-2)" "unprognostic (1.57e-1)" "potential prognostic favorable (1.90e-8)" "unprognostic (1.66e-2)" "unprognostic (8.73e-2)" "unprognostic (2.19e-2)" "unprognostic (5.05e-2)" "unprognostic (1.96e-1)" "unprognostic (1.08e-1)" "unprognostic (4.63e-2)" "unprognostic (4.12e-1)" "unprognostic (1.81e-1)" "unprognostic (1.08e-2)" "unprognostic (7.49e-2)" "unprognostic (2.32e-1)" "unprognostic (1.92e-1)" "unprognostic (9.44e-3)" "unprognostic (1.62e-1)" "unprognostic (4.01e-3)" "unprognostic (3.29e-1)" "unprognostic (1.77e-1)" "unprognostic (2.51e-1)" "unprognostic (3.08e-2)" FIGLA "bHLHc8, Figalpha" ENSG00000183733 "Folliculogenesis specific bHLH transcription factor" Q6QHK4 2 70777310-70790643 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Oogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "ovary: 2.9;retina: 1.0" "Cell type enriched" "Detected in some" 108 "Oocytes: 1556.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA071241 Supported NA NA "Cluster 75: Ovary - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 41: Oocytes - Oogenesis" 12 "HPA071241: " FIGN ENSG00000182263 "Fidgetin, microtubule severing factor" Q5HY92 2 163593396-163736012 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 492.1;Astrocytes: 286.7;Bergmann glia: 571.0;Leydig cells: 342.0;Oligodendrocyte progenitor cells: 468.7;Oligodendrocytes: 368.5;Other brain neurons: 298.0;Pituitary stem cells: 841.0;Podocytes: 365.2;Schwann cells: 422.5" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 849.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 33 "basophil: 3.3" "Lineage enriched" "Detected in single" 33 "granulocytes: 3.3" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA034987 Approved NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 65: Non-specific - Unknown function" "Cluster 61: Schwann cells & Melanocytes - Mixed function" 2 "HPA034987: " "unprognostic (2.98e-1)" "unprognostic (1.77e-1)" "unprognostic (2.20e-1)" "unprognostic (9.81e-3)" "unprognostic (1.63e-1)" "unprognostic (2.77e-2)" "unprognostic (1.40e-1)" "unprognostic (5.99e-2)" "unprognostic (2.97e-1)" "unprognostic (2.89e-1)" "unprognostic (5.70e-2)" "unprognostic (6.91e-2)" "unprognostic (2.59e-3)" "unprognostic (1.02e-1)" "unprognostic (2.64e-2)" FIGNL1 ENSG00000132436 "Fidgetin like 1" Q6PIW4 7 50444128-50542535 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 42.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA055542 Approved NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 10 "HPA055542: " "unprognostic (1.76e-1)" "unprognostic (2.94e-2)" "unprognostic (3.50e-2)" "unprognostic (2.71e-1)" "unprognostic (7.21e-2)" "unprognostic (1.54e-1)" "unprognostic (9.27e-2)" "unprognostic (7.98e-2)" "unprognostic (7.79e-2)" "potential prognostic unfavorable (1.00e-3)" "unprognostic (5.20e-3)" "unprognostic (2.11e-1)" "unprognostic (4.85e-2)" "potential prognostic unfavorable (1.20e-4)" "unprognostic (3.00e-3)" "unprognostic (1.58e-2)" "unprognostic (1.13e-2)" "unprognostic (4.02e-2)" "unprognostic (1.43e-2)" "unprognostic (4.12e-1)" "unprognostic (6.82e-2)" "unprognostic (1.32e-1)" "unprognostic (1.94e-3)" "unprognostic (4.56e-2)" "unprognostic (1.58e-3)" "unprognostic (3.22e-2)" "unprognostic (1.55e-2)" "unprognostic (3.62e-1)" "unprognostic (2.00e-1)" "unprognostic (1.04e-1)" "unprognostic (5.54e-2)" FIGNL2 ENSG00000261308 "Fidgetin like 2" A6NMB9 12 51817899-51848718 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 3.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 8.3;Late spermatids: 19.3;Loop of henle epithelial cells: 26.0;Lymphatic endothelial cells: 10.3;Müller glia: 10.5;Proximal tubule cells: 43.3;Retinal amacrine cells: 7.7" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Kidney Renal Papillary Cell Carcinoma (TCGA): 5.0;Testicular Germ Cell Tumor (TCGA): 5.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "testis cancer: 11.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 15: Non-specific - Transcription" "Cluster 34: Testis cancer - Unknown function" "Cluster 88: Proximal tubular cells - Transmembrane transport" "unprognostic (6.34e-2)" "unprognostic (9.38e-3)" "unprognostic (7.46e-2)" "unprognostic (5.72e-2)" "unprognostic (3.87e-3)" "unprognostic (4.73e-2)" "unprognostic (4.68e-2)" "unprognostic (8.02e-2)" "unprognostic (2.77e-1)" FILIP1 "FILIP, KIAA1275" ENSG00000118407 "Filamin A interacting protein 1" Q7Z7B0 6 75291859-75493800 "Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 50.3;skeletal muscle: 33.8;tongue: 45.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 196.7;Cardiomyocytes: 728.4;Corticotrophs: 340.6;Fibro-adipogenic progenitors: 226.6;Myonuclei: 1223.6;Respiratory ciliated cells: 213.5;Smooth muscle cells: 653.5;Thymic myoid cells: 732.8;Vascular smooth muscle cells: 319.3" "Cell type enriched" "Detected in all" 6 "vascular associated smooth muscle cell: 405.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "ovarian cancer: 3.0" "Breast - Endothelial cells, Heart muscle - Cardiomyocytes, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA053564 Enhanced Approved "Plasma membrane,Actin filaments" No NA "Cluster 41: Striated muscle - Muscle contraction" "Cluster 29: Forebrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 62: Smooth muscle cells - Muscle contraction" 3 "Plasma membrane, Actin filaments" "HPA053564: " "unprognostic (1.01e-2)" "unprognostic (1.16e-1)" "unprognostic (2.34e-1)" "unprognostic (2.01e-2)" "unprognostic (2.21e-1)" "unprognostic (4.71e-1)" "unprognostic (7.17e-2)" "potential prognostic favorable (6.95e-6)" "unprognostic (1.47e-3)" "unprognostic (1.17e-2)" "unprognostic (7.89e-2)" "unprognostic (6.13e-2)" "unprognostic (1.02e-2)" "unprognostic (4.39e-2)" "unprognostic (2.46e-2)" "unprognostic (7.26e-2)" "unprognostic (2.86e-1)" "unprognostic (9.91e-2)" "unprognostic (1.08e-1)" "unprognostic (1.11e-2)" "unprognostic (1.78e-1)" "unprognostic (2.57e-2)" FILIP1L "DOC-1, GIP130" ENSG00000168386 "Filamin A interacting protein 1 like" Q4L180 3 99828811-100114513 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 191.1" "Cell type enhanced" "Detected in many" "Early spermatids: 930.7;Epicardial cells: 1043.8;Late spermatids: 2461.5;Myonuclei: 5255.7;Vascular smooth muscle cells: 638.9" "Cell type enhanced" "Detected in all" "vascular associated smooth muscle cell: 564.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 3.0" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "liver cancer: 34.9;Rhabdoid: 38.7" "Adrenal gland - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Minor Salivary Gland - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in many" 7 "olfactory bulb: 18.0" "Low region specificity" "Detected in all" HPA043133 Approved Approved "Plasma membrane" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 24: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" "Plasma membrane" "HPA043133: " "unprognostic (2.22e-2)" "unprognostic (2.32e-1)" "unprognostic (2.99e-1)" "unprognostic (1.83e-2)" "unprognostic (7.08e-2)" "unprognostic (1.08e-1)" "unprognostic (1.56e-1)" "unprognostic (1.84e-2)" "unprognostic (1.96e-2)" "unprognostic (2.53e-1)" "potential prognostic favorable (2.36e-4)" "unprognostic (1.50e-3)" "unprognostic (5.26e-2)" "unprognostic (6.28e-2)" "unprognostic (5.31e-2)" "unprognostic (3.52e-1)" "unprognostic (1.71e-1)" "unprognostic (5.87e-2)" "unprognostic (2.46e-2)" "unprognostic (7.89e-2)" "potential prognostic unfavorable (2.03e-4)" "unprognostic (1.07e-1)" "unprognostic (4.50e-2)" "unprognostic (2.10e-1)" "unprognostic (3.09e-2)" "unprognostic (9.50e-3)" "unprognostic (5.13e-2)" "unprognostic (1.08e-2)" "unprognostic (3.89e-2)" "unprognostic (8.38e-2)" "unprognostic (1.38e-1)" FIP1L1 "DKFZp586K0717, FIP1, hFip1" ENSG00000145216 "Factor interacting with PAPOLA and CPSF1" Q6UN15 4 53377569-53464382 "Cancer-related genes, Disease related genes, Essential proteins, Predicted intracellular proteins" "mRNA processing" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 118.1;Megakaryocytes: 68.0;Oocytes: 147.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "HPA037475, HPA058202, HPA079225, HPA079228" Supported Enhanced Nucleoplasm NA NA 14000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 39: Testis - Nuclear processes" "Cluster 16: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 32 Nucleoplasm "HPA037475: , HPA058202: , HPA079225: , HPA079228: " "unprognostic (1.37e-1)" "unprognostic (2.19e-1)" "unprognostic (3.28e-2)" "unprognostic (3.22e-2)" "unprognostic (8.62e-2)" "unprognostic (1.94e-2)" "unprognostic (5.16e-2)" "unprognostic (7.61e-3)" "unprognostic (2.30e-1)" "potential prognostic unfavorable (7.35e-5)" "validated prognostic favorable (8.27e-6)" "validated prognostic favorable (5.85e-4)" "unprognostic (2.54e-2)" "unprognostic (1.80e-3)" "unprognostic (4.23e-2)" "potential prognostic unfavorable (9.98e-4)" "unprognostic (6.25e-3)" "unprognostic (3.03e-1)" "unprognostic (4.31e-3)" "unprognostic (2.29e-1)" "unprognostic (1.03e-1)" "unprognostic (1.66e-1)" "unprognostic (2.26e-1)" "unprognostic (9.49e-2)" "unprognostic (3.82e-2)" "unprognostic (1.68e-1)" "unprognostic (5.77e-2)" "unprognostic (8.98e-2)" "unprognostic (1.46e-1)" "unprognostic (5.69e-2)" "unprognostic (1.15e-1)" FIS1 "CGI-135, H_NH0132A01.6, TTC11" ENSG00000214253 "Fission, mitochondrial 1" Q9Y3D6 7 101239458-101252316 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 1219.0;Thymic myoid cells: 734.2" "Cell type enhanced" "Detected in all" "oligodendrocyte: 190.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017430 Approved Supported Mitochondria NA NA 55000 "Cluster 29: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 39: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 40 Mitochondria "HPA017430: " "unprognostic (3.94e-1)" "unprognostic (3.99e-2)" "potential prognostic unfavorable (3.73e-4)" "unprognostic (5.04e-2)" "unprognostic (2.54e-1)" "unprognostic (1.24e-2)" "unprognostic (2.38e-2)" "unprognostic (1.81e-1)" "unprognostic (2.76e-2)" "potential prognostic unfavorable (5.46e-4)" "potential prognostic favorable (2.03e-6)" "unprognostic (3.94e-2)" "potential prognostic favorable (4.94e-4)" "unprognostic (2.68e-1)" "unprognostic (4.95e-2)" "unprognostic (1.77e-1)" "unprognostic (7.18e-2)" "unprognostic (3.70e-1)" "unprognostic (2.70e-1)" "unprognostic (3.39e-1)" "unprognostic (8.24e-2)" "unprognostic (1.61e-2)" "unprognostic (8.42e-2)" "unprognostic (1.16e-1)" "unprognostic (1.50e-1)" "unprognostic (1.42e-1)" "unprognostic (2.44e-1)" "unprognostic (3.21e-3)" "unprognostic (3.96e-1)" "unprognostic (1.82e-1)" "unprognostic (3.43e-2)" FITM1 FIT1 ENSG00000139914 "Fat storage inducing transmembrane protein 1" A5D6W6 14 24130659-24132849 "Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "heart muscle: 163.8;skeletal muscle: 218.2" "Cell type enhanced" "Detected in some" "Astrocytes: 1.7;Proximal tubule cells: 1.1;Renal connecting tubule cells: 1.1;Thymic myoid cells: 1.4" "Low cell type specificity" "Detected in some" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA019842 Uncertain NA NA "Cluster 52: Non-specific - Cellular respiration" "Cluster 25: Non-specific - Transcription" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 102: Non-specific - Mixed function" "HPA019842: " "unprognostic (1.68e-1)" "unprognostic (6.56e-2)" FITM2 "C20orf142, dJ881L22.2, FIT2" ENSG00000197296 "Fat storage inducing transmembrane protein 2" Q8N6M3 20 44302840-44311202 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid metabolism" Hydrolase "Deafness, Disease variant, Dystonia, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 62.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 36.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Skin - Sebaceous gland cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 35: Non-specific - Mixed function" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 62: Non-specific - Plasma proteins" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 6 "unprognostic (3.96e-1)" "unprognostic (1.66e-2)" "unprognostic (3.42e-2)" "unprognostic (1.40e-3)" "unprognostic (7.23e-2)" "unprognostic (4.81e-3)" "unprognostic (2.59e-1)" "unprognostic (5.29e-2)" "unprognostic (3.16e-3)" "unprognostic (2.70e-2)" "potential prognostic favorable (5.85e-9)" "unprognostic (1.66e-2)" "unprognostic (1.54e-2)" "unprognostic (2.41e-2)" "unprognostic (5.01e-2)" "unprognostic (1.36e-2)" "unprognostic (2.57e-1)" "unprognostic (7.17e-2)" "unprognostic (8.87e-2)" "unprognostic (3.57e-2)" "potential prognostic unfavorable (6.31e-4)" "unprognostic (2.49e-2)" "unprognostic (1.86e-1)" "unprognostic (1.62e-1)" "potential prognostic favorable (6.95e-4)" "unprognostic (1.55e-1)" "unprognostic (3.02e-1)" "unprognostic (2.62e-1)" "unprognostic (2.26e-1)" "potential prognostic unfavorable (8.67e-4)" "unprognostic (4.71e-2)" FIZ1 "FLJ14768, ZNF798" ENSG00000179943 "FLT3 interacting zinc finger 1" Q96SL8 19 55591376-55601970 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 21.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074026 Approved Nucleoplasm NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 89: Adipocytes - Lipid metabolism" 1 Nucleoplasm "HPA074026: " "unprognostic (1.20e-3)" "unprognostic (1.70e-2)" "unprognostic (9.90e-3)" "potential prognostic unfavorable (7.81e-4)" "unprognostic (1.25e-1)" "unprognostic (3.51e-1)" "unprognostic (1.14e-1)" "unprognostic (1.26e-1)" "unprognostic (8.69e-2)" "unprognostic (4.14e-2)" "unprognostic (1.08e-2)" "unprognostic (1.98e-3)" "unprognostic (3.31e-3)" "unprognostic (2.31e-2)" "unprognostic (7.53e-2)" "unprognostic (3.25e-2)" "unprognostic (4.27e-1)" "unprognostic (2.11e-2)" "potential prognostic favorable (9.55e-4)" "unprognostic (2.60e-1)" "unprognostic (8.60e-2)" "potential prognostic favorable (9.87e-4)" "unprognostic (3.48e-2)" "unprognostic (5.58e-2)" "unprognostic (2.39e-1)" "unprognostic (8.15e-2)" "unprognostic (1.07e-2)" "unprognostic (1.78e-1)" "unprognostic (1.35e-1)" "unprognostic (6.79e-2)" "unprognostic (2.14e-1)" FJX1 "FLJ22416, FLJ25593" ENSG00000179431 "Four-jointed box kinase 1" Q86VR8 11 35618460-35620865 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 24.5;Basal keratinocytes: 25.1;Bergmann glia: 39.3;Breast myoepithelial cells: 31.9;Cytotrophoblasts: 34.0;Endometrial ciliated cells: 32.3;Endometrial secretory cells: 24.0;Endometrial stromal cells: 23.4;Epididymal basal cells: 37.7;Pancreatic duct cells: 21.7;Pericytes: 23.4" "Cell type enhanced" "Detected in many" "Bergmann glia: 52.4" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 49.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059220 Uncertain Approved Vesicles "Intracellular and membrane" "No annotated function" NA NA "Cluster 65: Brain - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 72: Neuronal - Signal transduction" "Cluster 17: Non-specific - RNA processing" Vesicles "HPA059220: " "unprognostic (3.28e-3)" "unprognostic (2.49e-1)" "unprognostic (1.03e-1)" "unprognostic (4.13e-2)" "unprognostic (1.16e-2)" "unprognostic (1.73e-1)" "unprognostic (2.47e-1)" "unprognostic (1.24e-1)" "unprognostic (1.47e-2)" "unprognostic (4.97e-2)" "unprognostic (2.14e-1)" "unprognostic (3.29e-1)" "potential prognostic unfavorable (8.84e-4)" "unprognostic (8.95e-2)" "unprognostic (4.60e-2)" "potential prognostic unfavorable (5.22e-6)" "unprognostic (1.22e-3)" "unprognostic (3.14e-1)" "unprognostic (1.52e-1)" "unprognostic (8.76e-2)" "unprognostic (3.37e-1)" "unprognostic (1.09e-2)" "unprognostic (3.94e-2)" "unprognostic (1.20e-1)" "unprognostic (2.17e-1)" "unprognostic (2.67e-1)" "unprognostic (3.18e-1)" "unprognostic (3.25e-3)" "unprognostic (1.48e-1)" "unprognostic (1.30e-2)" "unprognostic (2.32e-1)" FKBP10 "FKBP6, FKBP65, FLJ20683, FLJ22041, FLJ23833, hFKBP65" ENSG00000141756 "FKBP prolyl isomerase 10" Q96AY3 17 41812680-41823213 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Isomerase, Rotamase" "Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 244.2;Endometrial stromal cells: 79.4;Fibroblasts: 102.3;Granulosa cells: 60.0;Hepatic stellate cells: 135.6;Lactotrophs: 74.9;Leydig cells: 63.2;Müller glia: 59.2;Ovarian stromal cells: 62.0;Pericytes: 61.6;Peritubular myoid cells: 58.9" "Cell type enhanced" "Detected in many" "astrocyte: 53.9;Bergmann glia: 42.9;fibroblast: 49.8;pericyte: 41.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Lung - Fibroblasts_2, Prostate - Fibroblasts, Skin - Fibroblasts_2, Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013808, HPA051171, HPA057021" Enhanced Approved "Golgi apparatus" "Intracellular and membrane" Enzyme NA NA 84000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 10 "Golgi apparatus" "HPA013808: , HPA051171: , HPA057021: " "unprognostic (1.42e-1)" "unprognostic (1.12e-1)" "unprognostic (1.58e-1)" "potential prognostic unfavorable (8.49e-4)" "unprognostic (1.61e-1)" "unprognostic (1.11e-1)" "unprognostic (3.25e-2)" "unprognostic (3.15e-3)" "unprognostic (2.39e-2)" "unprognostic (5.68e-3)" "validated prognostic unfavorable (1.91e-7)" "validated prognostic unfavorable (4.93e-6)" "potential prognostic unfavorable (7.58e-4)" "unprognostic (1.86e-2)" "unprognostic (1.23e-1)" "unprognostic (1.94e-3)" "potential prognostic unfavorable (7.25e-4)" "unprognostic (5.24e-2)" "unprognostic (3.56e-1)" "unprognostic (5.39e-2)" "unprognostic (1.75e-1)" "unprognostic (1.19e-1)" "unprognostic (4.77e-2)" "unprognostic (4.12e-1)" "unprognostic (1.99e-1)" "unprognostic (1.71e-2)" "unprognostic (3.63e-3)" "unprognostic (1.68e-2)" "unprognostic (7.60e-2)" "potential prognostic unfavorable (4.56e-4)" "unprognostic (1.69e-1)" FKBP11 FKBP19 ENSG00000134285 "FKBP prolyl isomerase 11" Q9NYL4 12 48921518-48926474 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 466.6" "Cell type enriched" "Detected in many" 4 "Plasma cells: 1300.2" "Cell type enhanced" "Detected in many" "leukocyte: 27.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "MAIT T-cell: 188.7" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Myeloma: 357.0" "Breast - Plasma cells, Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Endothelial cells, Spleen - Plasma cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041709 Enhanced Approved Centrosome NA NA 4000000 "Cluster 24: Non-specific - Transcription" "Cluster 8: Pancreas - Proteolysis" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 67: Plasma cells - Plasma cell differentiation" 2 Centrosome "HPA041709: " "unprognostic (1.12e-2)" "unprognostic (1.30e-3)" "unprognostic (1.76e-1)" "unprognostic (9.84e-2)" "unprognostic (1.80e-1)" "unprognostic (3.80e-1)" "unprognostic (3.89e-3)" "unprognostic (1.20e-1)" "unprognostic (2.55e-1)" "unprognostic (6.18e-2)" "validated prognostic unfavorable (9.53e-9)" "validated prognostic unfavorable (1.71e-6)" "unprognostic (2.44e-3)" "unprognostic (6.95e-3)" "potential prognostic unfavorable (6.38e-5)" "unprognostic (1.14e-1)" "unprognostic (8.80e-2)" "unprognostic (5.35e-2)" "unprognostic (1.14e-1)" "unprognostic (8.30e-2)" "unprognostic (1.89e-2)" "unprognostic (1.19e-1)" "unprognostic (1.49e-1)" "unprognostic (3.90e-1)" "unprognostic (5.29e-2)" "unprognostic (2.19e-1)" "unprognostic (3.89e-2)" "unprognostic (9.47e-2)" "unprognostic (2.30e-1)" "unprognostic (9.22e-2)" "unprognostic (9.72e-2)" FKBP14 "FKBP22, FLJ20731" ENSG00000106080 "FKBP prolyl isomerase 14" Q9NWM8 7 30010587-30026702 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Isomerase, Rotamase" "Deafness, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Somatotrophs: 85.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013329, HPA026829" Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" "Intracellular and membrane" Enzyme NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 67: Non-specific - Unknown function" "Cluster 8: Non-specific - Secretory pathway" 24 Cytosol "Nucleoplasm, Golgi apparatus" "HPA013329: , HPA026829: " "unprognostic (2.42e-2)" "unprognostic (5.44e-3)" "unprognostic (6.69e-3)" "potential prognostic unfavorable (9.22e-4)" "unprognostic (1.14e-2)" "unprognostic (3.11e-1)" "unprognostic (4.03e-1)" "unprognostic (4.13e-3)" "unprognostic (1.05e-3)" "unprognostic (1.01e-1)" "unprognostic (1.12e-1)" "unprognostic (2.18e-1)" "unprognostic (3.92e-3)" "unprognostic (1.32e-3)" "unprognostic (2.87e-1)" "unprognostic (2.00e-2)" "unprognostic (2.14e-2)" "unprognostic (1.19e-1)" "unprognostic (2.40e-1)" "unprognostic (1.05e-1)" "unprognostic (1.08e-3)" "unprognostic (2.06e-2)" "unprognostic (9.31e-3)" "unprognostic (2.13e-1)" "unprognostic (3.82e-1)" "unprognostic (3.52e-2)" "unprognostic (2.05e-2)" "unprognostic (6.25e-3)" "unprognostic (1.73e-1)" "unprognostic (6.89e-3)" "unprognostic (2.51e-1)" FKBP15 "FKBP133, KIAA0674, PPP1R76, WAFL" ENSG00000119321 "FKBP prolyl isomerase family member 15" Q5T1M5 9 113161006-113221458 "Predicted intracellular proteins" "Endocytosis, Transport" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Kupffer cells: 137.3;Microglia: 123.9;monocytes: 121.9;Neutrophils: 178.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 5.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007979 Approved Approved Nucleoli,Cytosol NA NA 3900 "Cluster 2: Dendritic cells - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 11: White matter - Signal transduction" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 26 Nucleoli Cytosol "HPA007979: " "unprognostic (2.50e-1)" "unprognostic (1.98e-1)" "unprognostic (9.93e-2)" "unprognostic (4.86e-2)" "unprognostic (3.77e-3)" "unprognostic (3.50e-2)" "unprognostic (1.10e-1)" "unprognostic (1.91e-2)" "unprognostic (2.07e-1)" "unprognostic (1.16e-2)" "potential prognostic favorable (2.94e-4)" "unprognostic (1.78e-2)" "unprognostic (1.52e-1)" "unprognostic (3.48e-3)" "unprognostic (1.77e-1)" "unprognostic (2.31e-1)" "unprognostic (7.01e-3)" "unprognostic (1.13e-1)" "unprognostic (3.43e-1)" "unprognostic (6.21e-2)" "unprognostic (4.75e-1)" "unprognostic (1.08e-1)" "unprognostic (1.62e-2)" "unprognostic (1.15e-1)" "unprognostic (3.78e-2)" "unprognostic (7.89e-2)" "unprognostic (2.77e-1)" "unprognostic (2.43e-1)" "unprognostic (1.23e-3)" "unprognostic (3.00e-2)" "unprognostic (6.74e-2)" FKBP1A "FKBP-12, FKBP1, FKBP12, FKBP12C, PKC12, PPIASE" ENSG00000088832 "FKBP prolyl isomerase 1A" P62942 20 1368977-1393164 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Isomerase, Rotamase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 37.0;Extravillous trophoblasts: 27.5;Hofbauer cells: 24.7;Late primary spermatocytes: 25.6;Late spermatids: 30.3;Megakaryocytes: 30.9;Platelets: 33.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "dendritic cells: 675.8;granulocytes: 976.4;monocytes: 1017.4" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "CAB004639, HPA051330, HPA051798" Uncertain Approved "Golgi apparatus,Primary cilium,Basal body,Cytosol" NA NA 19000000 "Cluster 29: Non-specific - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 33: Neurons - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 23 "Golgi apparatus" "Primary cilium, Basal body, Cytosol" "CAB004639: , HPA051330: , HPA051798: " "unprognostic (1.31e-2)" "unprognostic (1.54e-2)" "unprognostic (2.47e-1)" "unprognostic (2.92e-1)" "unprognostic (8.04e-2)" "unprognostic (2.29e-2)" "unprognostic (4.89e-1)" "unprognostic (3.60e-3)" "unprognostic (1.93e-3)" "unprognostic (5.14e-2)" "potential prognostic favorable (2.11e-6)" "unprognostic (3.29e-2)" "unprognostic (7.51e-2)" "validated prognostic unfavorable (2.53e-7)" "validated prognostic unfavorable (7.09e-5)" "unprognostic (3.28e-2)" "unprognostic (5.05e-3)" "potential prognostic unfavorable (1.91e-4)" "unprognostic (7.72e-3)" "unprognostic (1.51e-1)" "unprognostic (3.94e-1)" "unprognostic (5.54e-3)" "unprognostic (1.46e-2)" "unprognostic (3.20e-1)" "unprognostic (1.25e-1)" "unprognostic (4.94e-2)" "unprognostic (1.38e-1)" "unprognostic (9.61e-3)" "unprognostic (2.42e-1)" "unprognostic (2.77e-2)" "unprognostic (1.47e-1)" FKBP1B "FKBP12.6, FKBP1L, FKBP9, OTK4, PPIase" ENSG00000119782 "FKBP prolyl isomerase 1B" P68106 2 24049701-24063681 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 73.7" "Group enriched" "Detected in many" 5 "Megakaryocytes: 383.3;Platelets: 129.2" "Cell type enhanced" "Detected in all" "hippocampal CA4: 39.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 2.2;T-reg: 2.8" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "testis cancer: 42.5" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045572, HPA051330, HPA051798" Uncertain Approved "Golgi apparatus,Vesicles,Primary cilium,Basal body,Cytosol" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 47: Platelets - Hemostasis" 9 "Golgi apparatus, Vesicles" "Primary cilium, Basal body, Cytosol" "HPA045572: , HPA051330: , HPA051798: " "unprognostic (2.51e-2)" "unprognostic (2.96e-2)" "unprognostic (3.89e-1)" "unprognostic (1.65e-1)" "unprognostic (1.77e-1)" "unprognostic (2.16e-2)" "unprognostic (2.25e-2)" "unprognostic (8.43e-3)" "unprognostic (1.90e-1)" "unprognostic (4.20e-1)" "unprognostic (7.61e-3)" "unprognostic (1.74e-2)" "unprognostic (1.84e-2)" "unprognostic (7.21e-3)" "unprognostic (2.72e-2)" "unprognostic (2.03e-1)" "unprognostic (3.09e-1)" "unprognostic (1.11e-1)" "unprognostic (1.64e-1)" "unprognostic (3.44e-1)" "unprognostic (3.96e-1)" "unprognostic (1.80e-1)" "unprognostic (2.20e-2)" "unprognostic (1.52e-2)" "unprognostic (3.01e-1)" "unprognostic (2.40e-1)" "unprognostic (3.27e-2)" "unprognostic (1.60e-1)" "unprognostic (7.48e-2)" "unprognostic (1.12e-1)" "unprognostic (2.00e-2)" FKBP1C bA184C23.2 ENSG00000198225 "FKBP prolyl isomerase family member 1C" 6 63211446-63213024 "Enzymes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Esophageal apical cells: 2.1;Esophageal suprabasal cells: 1.2;Gastric chief cells: 1.1;Parietal cells: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "dendritic cells: 3.0;granulocytes: 4.4;monocytes: 5.1" "Not detected" "Not detected" "HPA051330, HPA051798" Uncertain Approved "Golgi apparatus,Primary cilium,Basal body,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 74: Non-specific - Signal transduction" "Cluster 61: BICR 18 - Protein kinases" "Cluster 105: Non-specific - Mixed function" "Golgi apparatus" "Primary cilium, Basal body, Cytosol" "HPA051330: , HPA051798: " "unprognostic (2.15e-3)" "unprognostic (2.24e-1)" FKBP2 "FKBP-13, FKBP13, PPIase" ENSG00000173486 "FKBP prolyl isomerase 2" P26885 11 64241003-64244132 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 35.2;Bergmann glia: 30.4;Brain excitatory neurons: 32.6;Brain inhibitory neurons: 34.2;Choroid plexus epithelial cells: 34.4;Endometrial secretory cells: 46.3;Ependymal cells: 38.2;Hepatocytes: 52.7;Oligodendrocytes: 41.2;Other brain neurons: 50.1;Papillary tip epithelial cells: 30.5;Renal collecting duct principal cells: 32.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 931.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025561, HPA049405" Enhanced Approved "Plasma membrane" "Intracellular and membrane" Enzyme No No 570000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 70: Non-specific - Protein processing" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 63: Non-specific - Protein processing" "Cluster 98: Neurons - Neurotransmission & signaling" 15 "Plasma membrane" "CAB025561: , HPA049405: " "unprognostic (3.40e-1)" "unprognostic (8.71e-2)" "unprognostic (1.17e-2)" "unprognostic (1.18e-1)" "unprognostic (5.51e-2)" "unprognostic (1.72e-1)" "unprognostic (5.82e-2)" "unprognostic (1.38e-1)" "unprognostic (7.12e-2)" "potential prognostic unfavorable (1.67e-4)" "unprognostic (1.44e-2)" "unprognostic (1.93e-2)" "unprognostic (1.44e-3)" "unprognostic (4.69e-2)" "unprognostic (3.99e-1)" "unprognostic (3.01e-1)" "unprognostic (5.02e-2)" "unprognostic (9.68e-3)" "unprognostic (1.45e-1)" "unprognostic (2.97e-3)" "unprognostic (1.16e-2)" "unprognostic (1.36e-2)" "unprognostic (2.67e-1)" "unprognostic (1.36e-2)" "unprognostic (1.94e-2)" "unprognostic (1.86e-1)" "unprognostic (4.83e-2)" "unprognostic (1.89e-1)" "unprognostic (1.38e-1)" "unprognostic (3.03e-1)" "unprognostic (9.18e-2)" FKBP3 "FKBP-25, FKBP25" ENSG00000100442 "FKBP prolyl isomerase 3" Q00688 14 45115599-45135319 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 397.6;tongue: 347.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 410.8;Late spermatids: 621.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000864, CAB012232, CAB012520" Supported Supported Cytosol NA NA 460000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 34: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 15 Cytosol "CAB012232: , CAB012520: , HPA000864: " "unprognostic (2.04e-2)" "unprognostic (1.05e-1)" "unprognostic (1.34e-3)" "unprognostic (2.74e-2)" "unprognostic (1.30e-1)" "unprognostic (1.32e-1)" "unprognostic (2.44e-1)" "unprognostic (1.38e-1)" "unprognostic (4.89e-3)" "potential prognostic unfavorable (2.90e-4)" "unprognostic (2.86e-2)" "unprognostic (9.60e-2)" "unprognostic (1.01e-1)" "unprognostic (1.48e-3)" "unprognostic (2.11e-3)" "potential prognostic unfavorable (4.54e-4)" "unprognostic (2.50e-1)" "unprognostic (6.60e-3)" "unprognostic (2.71e-1)" "unprognostic (2.95e-2)" "unprognostic (2.62e-1)" "unprognostic (1.07e-1)" "unprognostic (6.53e-3)" "unprognostic (3.24e-2)" "unprognostic (5.03e-1)" "unprognostic (3.56e-2)" "unprognostic (2.54e-2)" "unprognostic (3.06e-1)" "unprognostic (1.64e-1)" "unprognostic (3.82e-1)" "unprognostic (4.08e-2)" FKBP4 "FKBP52, FKBP59" ENSG00000004478 "FKBP prolyl isomerase 4" Q02790 12 2794970-2805423 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Chaperone, Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 260.5;Esophageal apical cells: 252.2;Esophageal basal cells: 242.0;Esophageal suprabasal cells: 243.2;Late primary spermatocytes: 283.0;Migrating cytotrophoblasts: 230.3;Syncytiotrophoblasts: 276.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Prostate glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006148, CAB017441, HPA062857" Supported Supported Nucleoplasm,Cytosol NA NA 600000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 67: Testis - Mixed function" "Cluster 55: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 75: Non-specific - Chaperones and protein folding" 57 Cytosol Nucleoplasm "CAB017441: , HPA006148: , HPA062857: " "unprognostic (1.49e-2)" "unprognostic (3.23e-3)" "unprognostic (1.44e-1)" "unprognostic (8.90e-3)" "unprognostic (2.89e-1)" "unprognostic (1.24e-3)" "unprognostic (1.77e-1)" "unprognostic (1.17e-1)" "unprognostic (7.65e-2)" "unprognostic (5.97e-3)" "unprognostic (2.51e-2)" "unprognostic (1.05e-1)" "unprognostic (6.12e-3)" "validated prognostic unfavorable (4.21e-5)" "validated prognostic unfavorable (4.18e-5)" "potential prognostic unfavorable (4.68e-7)" "unprognostic (6.83e-2)" "unprognostic (2.12e-2)" "unprognostic (3.15e-1)" "unprognostic (1.13e-1)" "unprognostic (3.79e-2)" "unprognostic (9.02e-2)" "unprognostic (3.10e-2)" "unprognostic (7.03e-2)" "unprognostic (2.98e-2)" "unprognostic (1.30e-1)" "unprognostic (1.97e-1)" "unprognostic (6.61e-2)" "unprognostic (2.00e-1)" "unprognostic (1.46e-1)" "unprognostic (4.68e-2)" FKBP5 "FKBP51, FKBP54, P54, PPIase, Ptg-10" ENSG00000096060 "FKBP prolyl isomerase 5" Q13451 6 35573585-35728583 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Chaperone, Isomerase, Rotamase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 833.2;tongue: 864.2" "Cell type enhanced" "Detected in many" "Innate lymphoid cells: 1778.0;Monocyte progenitors: 2488.9;Neutrophils: 5747.7;Podocytes: 1716.6;Proximal tubule cells: 1851.2;Thymic myoid cells: 3630.2;Thymocytes: 1884.4" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 453.7;fibroblast: 344.6;leukocyte: 366.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "prostate cancer: 127.9" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009315, HPA031092, HPA031093, HPA031095" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" No No 14000 "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 24: Neutrophils - Innate immunity signal integration" 329 Nucleoplasm "Nucleoli fibrillar center, Cytosol" "CAB009315: , HPA031092: , HPA031093: , HPA031095: " "unprognostic (2.46e-2)" "unprognostic (4.08e-3)" "unprognostic (2.02e-1)" "unprognostic (2.87e-1)" "unprognostic (5.60e-2)" "unprognostic (1.16e-1)" "unprognostic (2.00e-2)" "unprognostic (1.18e-3)" "unprognostic (1.76e-1)" "unprognostic (1.03e-3)" "unprognostic (5.52e-2)" "unprognostic (1.65e-1)" "unprognostic (1.48e-1)" "unprognostic (2.31e-1)" "unprognostic (1.17e-1)" "potential prognostic unfavorable (8.60e-4)" "unprognostic (5.36e-2)" "unprognostic (4.50e-2)" "unprognostic (9.22e-2)" "unprognostic (2.23e-1)" "unprognostic (1.22e-2)" "unprognostic (2.27e-1)" "unprognostic (1.30e-1)" "unprognostic (1.31e-1)" "unprognostic (7.00e-3)" "unprognostic (9.21e-2)" "unprognostic (9.21e-3)" "unprognostic (9.13e-3)" "unprognostic (3.72e-2)" "unprognostic (1.28e-1)" "unprognostic (1.97e-1)" FKBP6 "FKBP36, PPIase" ENSG00000077800 "FKBP prolyl isomerase family member 6 (inactive)" O75344 7 73328161-73358637 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Differentiation, Meiosis, RNA-mediated gene silencing, Spermatogenesis" "Disease variant, Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 152 "testis: 53.0" "Group enriched" "Detected in some" 6 "Differentiating spermatogonia: 33.5;Early primary spermatocytes: 126.1;Early spermatids: 39.3;Late primary spermatocytes: 125.3;Late spermatids: 31.7;Oocytes: 41.4;Undifferentiated spermatogonia: 34.6" "Cell type enhanced" "Detected in some" "fibroblast: 2.1;oligodendrocyte: 1.8" "Cancer enhanced" "Detected in single" "Testicular Germ Cell Tumor (TCGA): 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Gallbladder cancer: 1.1" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041414, HPA061109" Enhanced Supported "Nucleoli fibrillar center,Microtubules,Cytokinetic bridge,Cytosol" Yes NA "Cluster 6: Testis - Spermatogenesis" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 51 "Nucleoli fibrillar center, Cytosol" "Microtubules, Cytokinetic bridge" "HPA041414: , HPA061109: " "unprognostic (1.73e-1)" FKBP7 FKBP23 ENSG00000079150 "FKBP prolyl isomerase 7" Q9Y680 2 178463664-178478600 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 52.9" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 168.2;Early spermatids: 259.3;Fibroblasts: 52.8;Hepatic stellate cells: 58.1;Late primary spermatocytes: 76.0;Late spermatids: 65.1;Leydig cells: 53.6;Ovarian stromal cells: 88.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Adrenal gland - Fibroblasts, Breast - Fibroblasts, Kidney - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008707 Approved Supported Approved "Endoplasmic reticulum" "Intracellular and membrane" Enzyme NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 75: Ovary - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 61 "Endoplasmic reticulum" "HPA008707: " "unprognostic (4.13e-1)" "unprognostic (6.01e-2)" "unprognostic (1.85e-1)" "unprognostic (1.03e-1)" "unprognostic (4.63e-2)" "unprognostic (3.90e-2)" "unprognostic (1.53e-1)" "unprognostic (4.99e-2)" "unprognostic (2.14e-2)" "unprognostic (2.02e-1)" "unprognostic (1.05e-3)" "unprognostic (3.92e-2)" "unprognostic (9.41e-2)" "unprognostic (4.73e-2)" "unprognostic (2.57e-1)" "unprognostic (3.74e-1)" "unprognostic (1.17e-2)" "unprognostic (1.42e-2)" "unprognostic (1.19e-1)" "unprognostic (5.49e-3)" "unprognostic (4.19e-3)" "unprognostic (4.90e-2)" "unprognostic (3.16e-1)" "unprognostic (2.80e-1)" "unprognostic (1.69e-1)" "unprognostic (1.73e-1)" "unprognostic (3.10e-3)" "potential prognostic unfavorable (6.67e-4)" "unprognostic (1.33e-1)" "unprognostic (8.65e-3)" "unprognostic (1.44e-1)" FKBP8 "FKBP38, FKBPr38" ENSG00000105701 "FKBP prolyl isomerase 8" Q14318 19 18531751-18544077 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Host-virus interaction" "Isomerase, Rotamase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 999.7;Late spermatids: 2216.9;Platelets: 649.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "eosinophil: 93.7;neutrophil: 78.5" "Lineage enriched" "Detected in all" 5 "granulocytes: 93.7" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025346, HPA045177" Supported Supported "Endoplasmic reticulum,Mitochondria,Cytosol" NA NA 6800 "Cluster 19: Eosinophils - Unknown function" "Cluster 78: Brain - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 23: Non-specific - Transcription" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 166 Mitochondria "Endoplasmic reticulum, Cytosol" "CAB025346: , HPA045177: " "unprognostic (2.21e-1)" "unprognostic (2.23e-1)" "unprognostic (1.18e-1)" "unprognostic (2.17e-1)" "unprognostic (7.18e-2)" "unprognostic (6.15e-2)" "unprognostic (1.55e-1)" "unprognostic (3.39e-1)" "unprognostic (4.64e-2)" "unprognostic (7.65e-2)" "unprognostic (1.94e-1)" "unprognostic (3.06e-1)" "unprognostic (1.94e-3)" "unprognostic (1.17e-3)" "unprognostic (7.12e-3)" "unprognostic (1.74e-1)" "unprognostic (3.16e-2)" "unprognostic (1.39e-2)" "unprognostic (1.79e-1)" "unprognostic (8.79e-2)" "unprognostic (2.37e-1)" "unprognostic (2.20e-3)" "unprognostic (1.55e-1)" "unprognostic (8.83e-2)" "unprognostic (6.20e-2)" "unprognostic (5.97e-2)" "unprognostic (1.12e-1)" "unprognostic (3.79e-1)" "unprognostic (4.94e-3)" "unprognostic (4.99e-2)" "unprognostic (1.25e-1)" FKBP9 "FKBP60, FKBP63" ENSG00000122642 "FKBP prolyl isomerase 9" O95302 7 32957404-33006930 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 90.4" "Cell type enhanced" "Detected in all" "endothelial cell: 105.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblasts_1, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012595, HPA055256" Approved Approved "Golgi apparatus" "Intracellular and membrane" Enzyme No No 140000 "Cluster 35: Neutrophils - Protein binding" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" "Golgi apparatus" "HPA012595: , HPA055256: " "potential prognostic unfavorable (8.51e-4)" "unprognostic (5.48e-3)" "unprognostic (9.18e-2)" "unprognostic (4.83e-2)" "unprognostic (4.30e-2)" "unprognostic (1.24e-1)" "unprognostic (4.74e-3)" "potential prognostic unfavorable (7.45e-7)" "potential prognostic unfavorable (3.19e-5)" "unprognostic (5.15e-2)" "unprognostic (8.35e-3)" "unprognostic (2.46e-1)" "unprognostic (2.02e-1)" "potential prognostic unfavorable (6.55e-4)" "unprognostic (1.27e-2)" "unprognostic (9.71e-3)" "unprognostic (1.56e-1)" "unprognostic (2.11e-1)" "unprognostic (1.65e-1)" "unprognostic (3.40e-1)" "unprognostic (2.06e-1)" "unprognostic (4.78e-2)" "unprognostic (1.00e-1)" "unprognostic (1.11e-1)" "unprognostic (3.55e-1)" "unprognostic (1.84e-2)" "unprognostic (1.28e-1)" "unprognostic (1.45e-2)" "unprognostic (2.28e-1)" "unprognostic (1.91e-3)" "unprognostic (1.42e-1)" FKBPL "DIR1, NG7, WISp39" ENSG00000204315 "FKBP prolyl isomerase like" Q9UIM3 6 32128707-32130288 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Bergmann glia: 1.3;Ependymal cells: 1.2;Oligodendrocytes: 1.0;Other brain neurons: 1.2;Platelets: 2.8;Renal collecting duct principal cells: 1.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043478, HPA060158" Approved Approved "Nucleoplasm,Mitotic spindle" Yes No "Cluster 18: Non-specific - Translation" "Cluster 2: Non-specific - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 98: Neurons - Neurotransmission & signaling" 17 Nucleoplasm "Mitotic spindle" "HPA043478: , HPA060158: " "unprognostic (1.48e-1)" "unprognostic (2.76e-2)" "unprognostic (8.00e-2)" "unprognostic (1.41e-1)" "unprognostic (1.61e-1)" "unprognostic (8.58e-3)" "unprognostic (4.00e-1)" "potential prognostic favorable (6.89e-4)" "unprognostic (1.51e-1)" "unprognostic (1.36e-2)" "unprognostic (3.77e-2)" "unprognostic (1.41e-1)" "unprognostic (1.85e-1)" "unprognostic (6.53e-2)" "unprognostic (4.68e-3)" "unprognostic (8.38e-2)" "unprognostic (3.20e-1)" "unprognostic (1.40e-2)" "unprognostic (8.32e-3)" "unprognostic (1.15e-2)" "unprognostic (2.65e-1)" "unprognostic (2.50e-2)" "unprognostic (4.47e-2)" "unprognostic (4.17e-1)" "unprognostic (9.82e-3)" "unprognostic (1.80e-1)" "unprognostic (3.28e-1)" "unprognostic (1.03e-1)" "unprognostic (4.07e-1)" "unprognostic (7.48e-2)" "potential prognostic favorable (9.61e-4)" FKRP "FKTR, LGMD2I, MDC1C" ENSG00000181027 "Fukutin related protein" Q9H9S5 19 46746046-46776988 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Transferase "Cardiomyopathy, Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Limb-girdle muscular dystrophy, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043115, HPA060454" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" "Secreted to blood" Enzyme NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 24: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 103: Non-specific - Basic cellular processes" 4 "Nucleoplasm, Golgi apparatus, Cytosol" "HPA043115: , HPA060454: " "unprognostic (3.47e-1)" "unprognostic (3.01e-1)" "unprognostic (8.09e-2)" "potential prognostic unfavorable (8.08e-4)" "unprognostic (4.43e-2)" "unprognostic (2.91e-1)" "unprognostic (6.96e-2)" "unprognostic (1.42e-2)" "unprognostic (2.05e-1)" "unprognostic (3.47e-1)" "unprognostic (3.46e-2)" "unprognostic (1.45e-2)" "unprognostic (1.94e-1)" "unprognostic (2.38e-2)" "unprognostic (3.87e-2)" "unprognostic (5.18e-2)" "unprognostic (7.63e-2)" "unprognostic (2.18e-1)" "unprognostic (1.37e-1)" "unprognostic (3.69e-2)" "unprognostic (5.46e-2)" "potential prognostic favorable (3.21e-4)" "unprognostic (1.25e-1)" "unprognostic (3.98e-1)" "unprognostic (2.61e-1)" "unprognostic (2.27e-1)" "unprognostic (1.15e-3)" "unprognostic (1.60e-1)" "unprognostic (1.55e-1)" "unprognostic (4.09e-2)" "unprognostic (1.57e-1)" FKTN "FCMD, LGMD2M" ENSG00000106692 Fukutin O75072 9 105558122-105653820 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Transferase "Cardiomyopathy, Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Limb-girdle muscular dystrophy, Lissencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 125.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012820 Approved NA NA "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Transcription" 2 "HPA012820: " "unprognostic (1.86e-3)" "unprognostic (5.21e-2)" "unprognostic (2.03e-1)" "unprognostic (1.56e-1)" "unprognostic (1.24e-1)" "unprognostic (1.91e-1)" "unprognostic (5.88e-2)" "unprognostic (1.31e-1)" "unprognostic (1.72e-1)" "unprognostic (1.22e-1)" "potential prognostic favorable (5.78e-7)" "unprognostic (1.01e-3)" "unprognostic (1.00e-1)" "potential prognostic unfavorable (6.46e-4)" "unprognostic (4.52e-2)" "unprognostic (9.85e-3)" "unprognostic (2.15e-2)" "unprognostic (2.21e-1)" "unprognostic (2.54e-1)" "unprognostic (4.37e-2)" "potential prognostic unfavorable (1.09e-4)" "unprognostic (5.44e-2)" "unprognostic (6.76e-2)" "unprognostic (1.25e-2)" "unprognostic (2.32e-2)" "unprognostic (1.65e-1)" "unprognostic (3.61e-1)" "unprognostic (1.50e-1)" "unprognostic (1.06e-1)" "unprognostic (9.56e-2)" "unprognostic (1.66e-1)" FLACC1 ALS2CR12 ENSG00000155749 "Flagellum associated containing coiled-coil domains 1" Q96Q35 2 201288271-201357398 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 8.5;testis: 16.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 66.7;Choroid plexus epithelial cells: 88.8;Early spermatids: 101.3;Ependymal cells: 168.9;Epididymal efferent duct ciliated cells: 87.3;Fallopian tube ciliated cells: 64.3;Late primary spermatocytes: 124.3;Respiratory ciliated cells: 146.9;Retinal bipolar cells: 61.2" "Cell type enhanced" "Detected in all" "ependymal cell: 180.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 3.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA035793 Approved "Plasma membrane,Cytosol,Connecting piece,Mid piece,Annulus" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 34: Ciliated cells - Cilia assembly & function" 9 "Cytosol, Connecting piece, Mid piece, Annulus" "Plasma membrane" "HPA035793: " "unprognostic (2.66e-2)" "unprognostic (1.15e-1)" "unprognostic (1.64e-1)" "unprognostic (4.55e-2)" "unprognostic (1.07e-3)" "unprognostic (1.66e-1)" "unprognostic (9.34e-3)" "unprognostic (1.82e-1)" "unprognostic (4.08e-1)" "unprognostic (8.34e-2)" "unprognostic (1.57e-2)" "unprognostic (1.07e-1)" "unprognostic (3.09e-1)" "unprognostic (1.91e-1)" "unprognostic (7.33e-2)" FLAD1 "FAD1, PP591" ENSG00000160688 "Flavin adenine dinucleotide synthetase 1" Q8NFF5 1 154983338-154993111 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 126.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028476, HPA028486, HPA028563" Approved Approved "Plasma membrane,Cytokinetic bridge,Primary cilium,Cytosol,Mid piece,Principal piece,End piece" Yes NA "Cluster 13: Non-specific - Mitochondria" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 97: Non-specific - Cellular respiration" 9 "Plasma membrane, Cytosol" "Cytokinetic bridge, Primary cilium, Mid piece, Principal piece, End piece" "HPA028476: , HPA028486: , HPA028563: " "unprognostic (2.45e-1)" "unprognostic (1.90e-2)" "unprognostic (4.03e-1)" "unprognostic (8.17e-2)" "unprognostic (3.07e-2)" "unprognostic (2.01e-2)" "unprognostic (3.45e-1)" "unprognostic (1.84e-3)" "unprognostic (2.46e-1)" "unprognostic (3.12e-2)" "potential prognostic unfavorable (2.46e-7)" "unprognostic (4.23e-3)" "unprognostic (4.57e-2)" "unprognostic (1.91e-3)" "unprognostic (3.65e-2)" "unprognostic (8.00e-3)" "unprognostic (2.08e-2)" "unprognostic (3.59e-2)" "unprognostic (6.66e-2)" "unprognostic (3.28e-1)" "unprognostic (2.80e-1)" "unprognostic (3.94e-2)" "unprognostic (5.97e-2)" "unprognostic (2.44e-2)" "unprognostic (3.73e-1)" "unprognostic (3.31e-1)" "unprognostic (1.71e-2)" "unprognostic (2.28e-2)" "unprognostic (1.60e-1)" "unprognostic (2.02e-2)" "unprognostic (8.04e-2)" FLCN "BHD, DENND8B, MGC17998, MGC23445" ENSG00000154803 Folliculin Q8NFG4 17 17212212-17237188 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "GTPase activation" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 5.1;Early spermatids: 4.4;Erythrocytes: 3.2;Late spermatids: 15.7;Retinal horizontal cells: 4.0" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015158, HPA028760" Supported Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 18 Cytosol "Vesicles, Plasma membrane" "CAB015158: , HPA028760: " "unprognostic (4.89e-3)" "unprognostic (1.01e-1)" "unprognostic (3.87e-3)" "unprognostic (3.74e-2)" "unprognostic (1.36e-2)" "unprognostic (6.12e-2)" "unprognostic (4.41e-2)" "unprognostic (2.58e-2)" "unprognostic (3.20e-1)" "unprognostic (1.47e-1)" "unprognostic (6.77e-2)" "unprognostic (1.11e-2)" "unprognostic (3.64e-2)" "unprognostic (5.59e-2)" "unprognostic (9.77e-2)" "unprognostic (2.83e-1)" "unprognostic (2.16e-2)" "unprognostic (1.38e-2)" "unprognostic (1.01e-1)" "unprognostic (8.33e-2)" "unprognostic (7.01e-2)" "unprognostic (3.35e-3)" "unprognostic (2.99e-2)" "unprognostic (4.67e-2)" "unprognostic (2.44e-1)" "unprognostic (1.07e-2)" "unprognostic (1.69e-2)" "unprognostic (3.85e-1)" "unprognostic (1.62e-1)" "unprognostic (5.99e-2)" "unprognostic (1.22e-1)" FLG ENSG00000143631 Filaggrin P20930 1 152302165-152325239 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Developmental protein" "Cancer-related genes, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 29 "skin 1: 432.6" "Cell type enriched" "Detected in some" 49 "Esophageal apical cells: 1977.9" "Cell type enhanced" "Detected in some" "fibroblast: 2.8" "Cancer enriched" "Detected in some" 7 "Skin Cutaneous Melanoma (TCGA): 27.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Brain cancer: 17.0;Kidney cancer: 20.6;ovarian cancer: 31.0;Uterine cancer: 37.8" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" "CAB002210, HPA027505, HPA030188, HPA030189" Enhanced Enhanced "Cytoplasmic bodies" NA NA 22000000 "Cluster 37: Skin - Keratinization" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 84: Apical squamous epithelium - Cornification" 18 "Cytoplasmic bodies" "CAB002210: , HPA027505: , HPA030188: , HPA030189: " "unprognostic (3.48e-2)" "unprognostic (9.60e-2)" "unprognostic (4.08e-1)" "unprognostic (9.80e-2)" "unprognostic (3.54e-2)" "unprognostic (2.90e-2)" FLG2 IFPS ENSG00000143520 "Filaggrin 2" Q5D862 1 152348735-152360006 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "skin 1: 456.4" "Cell type enhanced" "Detected in some" "Adipocytes: 3.2;Cardiomyocytes: 5.3;Cone photoreceptor cells: 2.1;Epicardial cells: 2.3;Esophageal apical cells: 1.9;Fibro-adipogenic progenitors: 3.1;Medullary thymic epithelial cells: 7.2;Myosatellite cells: 2.4;Suprabasal keratinocytes: 1.4" "Low cell type specificity" "Detected in single" "Cancer enriched" "Detected in some" 11 "Skin Cutaneous Melanoma (TCGA): 13.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Not detected" "Not detected" HPA028699 Approved NA NA 40000000 "Cluster 37: Skin - Keratinization" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 6 "HPA028699: " "unprognostic (2.15e-1)" "unprognostic (5.16e-2)" FLI1 "EWSR2, FLI-1, SIC-1" ENSG00000151702 "Fli-1 proto-oncogene, ETS transcription factor" Q01543 11 128686535-128813267 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 65.9" "Cell type enhanced" "Detected in many" "B-cells: 294.4;Hematopoietic stem cells: 388.7;Kupffer cells: 233.7;Lymphatic endothelial cells: 318.8;Macrophages: 258.1;Megakaryocyte progenitors: 736.7;Microglia: 514.2;Monocyte progenitors: 404.2;monocytes: 251.5;Neutrophil progenitors: 778.5;Neutrophils: 839.9;NK-cells: 256.8;Platelets: 244.1;T-cells: 223.2;Thymocytes: 269.3;Vascular endothelial cells: 529.2" "Group enriched" "Detected in many" 11 "central nervous system macrophage: 678.7;endothelial cell: 1439.5;leukocyte: 457.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 39.0;Myeloma: 29.4" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Lung - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Spleen - Endothelial cells, Testis - Endothelial cells, Thyroid gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065030, HPA073099" Approved Supported "Nucleoplasm,Nuclear bodies" Yes NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 104: Brain endothelial cells - Blood brain barrier" 11 "Nuclear bodies" Nucleoplasm "HPA065030: , HPA073099: " "unprognostic (1.26e-1)" "unprognostic (6.03e-2)" "unprognostic (7.07e-3)" "unprognostic (9.59e-2)" "unprognostic (6.28e-2)" "unprognostic (4.57e-2)" "unprognostic (1.74e-1)" "unprognostic (1.37e-1)" "unprognostic (4.97e-3)" "unprognostic (1.72e-2)" "validated prognostic favorable (6.17e-9)" "validated prognostic favorable (6.48e-4)" "unprognostic (1.48e-3)" "unprognostic (1.10e-2)" "unprognostic (3.08e-2)" "unprognostic (1.15e-1)" "unprognostic (9.11e-2)" "unprognostic (3.26e-1)" "unprognostic (3.47e-3)" "unprognostic (2.19e-2)" "unprognostic (4.15e-2)" "unprognostic (3.00e-3)" "unprognostic (1.81e-1)" "unprognostic (1.34e-1)" "unprognostic (1.61e-1)" "unprognostic (7.61e-2)" "unprognostic (2.90e-2)" "unprognostic (2.23e-2)" "unprognostic (8.62e-2)" "unprognostic (1.13e-2)" FLII "FLI, Fli1, FLIL, MGC39265" ENSG00000177731 "FLII actin remodeling protein" Q13045 17 18244815-18258738 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Actin-binding, Activator" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 239.7" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007084, HPA008903, CAB016132" Enhanced Approved "Nucleoplasm,Centriolar satellite,Cytosol" NA NA 170000 "Cluster 40: Monocytes - Innate immune response" "Cluster 24: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 102: Non-specific - Mixed function" 40 "Nucleoplasm, Centriolar satellite, Cytosol" "CAB016132: , HPA007084: , HPA008903: " "unprognostic (2.66e-1)" "unprognostic (5.53e-2)" "unprognostic (1.47e-2)" "potential prognostic unfavorable (5.11e-4)" "unprognostic (3.36e-1)" "unprognostic (4.45e-1)" "unprognostic (8.36e-2)" "unprognostic (2.22e-1)" "unprognostic (2.36e-1)" "unprognostic (4.71e-1)" "unprognostic (8.76e-3)" "unprognostic (9.63e-2)" "unprognostic (1.87e-2)" "unprognostic (8.60e-2)" "unprognostic (3.79e-1)" "unprognostic (1.41e-2)" "unprognostic (8.05e-2)" "unprognostic (1.45e-2)" "unprognostic (7.45e-3)" "unprognostic (4.05e-2)" "unprognostic (2.59e-3)" "unprognostic (3.95e-2)" "unprognostic (4.09e-3)" "unprognostic (1.50e-1)" "unprognostic (2.25e-1)" "unprognostic (3.47e-2)" "unprognostic (4.33e-1)" "unprognostic (3.36e-1)" "unprognostic (2.85e-1)" "unprognostic (1.37e-1)" "unprognostic (1.96e-2)" FLNA "ABP-280, FLN, FLN1, OPD1, OPD2" ENSG00000196924 "Filamin A" P21333 X 154348524-154374634 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Cilium biogenesis/degradation" Actin-binding "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 1674.2;intestine: 1114.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 700.6;Breast myoepithelial cells: 610.5;Decidual stromal cells: 464.1;Hepatic stellate cells: 451.8;Megakaryocytes: 519.3;Peritubular myoid cells: 522.7;Platelets: 2360.7;Smooth muscle cells: 2255.7;Vascular smooth muscle cells: 1439.3" "Cell type enriched" "Detected in all" 4 "vascular associated smooth muscle cell: 1014.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Colon - Smooth muscle cells, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Spleen - Fibroblasts_1, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000356, HPA000368, HPA001016, HPA001115, HPA002925" Enhanced Approved Supported "Plasma membrane,Actin filaments,Cytosol" NA NA 1000000000 "Cluster 33: Non-specific - ATP binding" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 12: Non-specific - Vasculature" "Cluster 36: Non-specific - mRNA processing" "Cluster 62: Smooth muscle cells - Muscle contraction" 117 "Plasma membrane, Actin filaments, Cytosol" "CAB000356: , HPA000368: , HPA001016: , HPA001115: , HPA002925: " "unprognostic (1.62e-1)" "unprognostic (8.63e-2)" "unprognostic (3.52e-2)" "unprognostic (6.01e-3)" "unprognostic (8.98e-2)" "unprognostic (1.47e-2)" "unprognostic (1.08e-1)" "unprognostic (1.04e-1)" "unprognostic (2.72e-2)" "unprognostic (2.06e-2)" "potential prognostic favorable (1.02e-5)" "unprognostic (1.05e-1)" "unprognostic (2.75e-2)" "unprognostic (1.30e-1)" "unprognostic (1.03e-1)" "unprognostic (2.70e-1)" "unprognostic (6.10e-3)" "unprognostic (7.27e-2)" "unprognostic (1.48e-1)" "unprognostic (1.17e-1)" "unprognostic (7.80e-2)" "unprognostic (2.66e-2)" "unprognostic (2.41e-1)" "unprognostic (1.09e-1)" "unprognostic (2.17e-1)" "unprognostic (5.24e-3)" "unprognostic (5.50e-2)" "unprognostic (3.45e-3)" "unprognostic (1.87e-1)" "unprognostic (1.16e-1)" "unprognostic (1.76e-1)" FLNB "ABP-278, FH1, FLN1L, LRS1, TABP, TAP" ENSG00000136068 "Filamin B" O75369 3 58008398-58172251 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Differentiation, Myogenesis" "Actin-binding, Developmental protein" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 779.3;Pancreatic acinar cells: 673.0;Prostatic glandular cells: 611.2;Urothelial cells: 613.5" "Cell type enhanced" "Detected in all" "endothelial cell: 440.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004747, HPA004886, CAB019322" Enhanced Supported "Golgi apparatus,Plasma membrane,Actin filaments,Cytosol" NA NA 19000000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 77: Intestine - Digestion" "Cluster 6: Non-specific - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 49 "Plasma membrane" "Golgi apparatus, Actin filaments, Cytosol" "CAB019322: , HPA004747: , HPA004886: " "unprognostic (2.33e-1)" "unprognostic (7.50e-2)" "unprognostic (2.44e-1)" "unprognostic (5.62e-3)" "unprognostic (2.15e-1)" "unprognostic (1.10e-3)" "unprognostic (3.24e-1)" "unprognostic (5.70e-2)" "unprognostic (1.58e-1)" "unprognostic (3.54e-1)" "unprognostic (3.52e-3)" "unprognostic (3.59e-2)" "potential prognostic favorable (2.52e-4)" "unprognostic (6.24e-3)" "unprognostic (6.68e-2)" "unprognostic (6.47e-2)" "unprognostic (8.29e-3)" "unprognostic (1.70e-1)" "unprognostic (1.74e-2)" "unprognostic (1.07e-1)" "unprognostic (3.58e-1)" "potential prognostic unfavorable (2.37e-4)" "unprognostic (6.14e-2)" "unprognostic (1.82e-1)" "unprognostic (8.77e-2)" "unprognostic (2.03e-2)" "unprognostic (2.05e-1)" "unprognostic (1.68e-1)" "unprognostic (3.51e-1)" "unprognostic (1.03e-1)" "unprognostic (2.95e-1)" FLNC "ABP-280, ABPL, FLN2" ENSG00000128591 "Filamin C" Q14315 7 128830406-128859274 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" Actin-binding "Cardiomyopathy, Disease variant, Myofibrillar myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 587.8;skeletal muscle: 1324.7;tongue: 413.4" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 127.5;Myonuclei: 137.4;Smooth muscle cells: 273.4;Thymic myoid cells: 165.9" "Cell type enhanced" "Detected in many" "astrocyte: 11.5;ependymal cell: 27.8;vascular associated smooth muscle cell: 12.2" "Cancer enhanced" "Detected in many" "Stomach Adenocarcinoma (TCGA): 45.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Smooth muscle cells, Colon - Smooth muscle cells, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Skin - Smooth muscle cells, Spleen - Smooth muscle cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA006135, HPA071007" Enhanced Approved "Plasma membrane,Cytosol" NA NA 26000000 "Cluster 25: Non-specific - Basic cellular processes" "Cluster 22: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 62: Smooth muscle cells - Muscle contraction" 42 "Plasma membrane, Cytosol" "HPA006135: , HPA071007: " "unprognostic (6.40e-3)" "unprognostic (9.74e-2)" "unprognostic (8.43e-2)" "unprognostic (7.18e-2)" "unprognostic (7.42e-2)" "unprognostic (3.21e-2)" "unprognostic (1.09e-3)" "potential prognostic unfavorable (1.77e-4)" "unprognostic (2.39e-3)" "unprognostic (5.73e-3)" "potential prognostic unfavorable (3.44e-4)" "unprognostic (5.48e-3)" "unprognostic (2.07e-1)" "unprognostic (3.06e-3)" "unprognostic (7.02e-3)" "potential prognostic unfavorable (1.44e-8)" "unprognostic (9.73e-3)" "unprognostic (1.89e-3)" "unprognostic (1.63e-1)" "unprognostic (7.06e-3)" "unprognostic (1.80e-1)" "potential prognostic unfavorable (5.02e-4)" "unprognostic (2.41e-1)" "unprognostic (3.64e-2)" "unprognostic (7.25e-3)" "unprognostic (3.94e-3)" "potential prognostic unfavorable (9.35e-4)" "unprognostic (7.70e-3)" "unprognostic (1.05e-1)" "unprognostic (1.06e-1)" FLOT1 ENSG00000137312 "Flotillin 1" O75955 6 30727709-30742732 "Plasma proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 140.1;Neutrophils: 132.3;Oocytes: 225.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 314.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001393, CAB007766" Enhanced Uncertain "Golgi apparatus,Vesicles,Plasma membrane" NA NA 58000 "Cluster 35: Neutrophils - Protein binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 62 "Golgi apparatus" "Vesicles, Plasma membrane" "CAB007766: , HPA001393: " "unprognostic (2.74e-1)" "unprognostic (3.06e-2)" "unprognostic (9.26e-3)" "potential prognostic unfavorable (1.29e-4)" "unprognostic (1.47e-1)" "unprognostic (6.65e-2)" "unprognostic (1.45e-1)" "unprognostic (2.06e-1)" "unprognostic (3.39e-2)" "unprognostic (1.18e-1)" "potential prognostic favorable (1.77e-4)" "unprognostic (4.01e-1)" "unprognostic (2.26e-1)" "validated prognostic unfavorable (7.93e-4)" "validated prognostic unfavorable (8.07e-4)" "unprognostic (2.46e-2)" "unprognostic (1.31e-1)" "potential prognostic unfavorable (9.13e-4)" "unprognostic (9.78e-2)" "unprognostic (2.50e-2)" "unprognostic (2.84e-1)" "unprognostic (1.05e-1)" "potential prognostic unfavorable (3.20e-5)" "unprognostic (3.77e-1)" "unprognostic (2.69e-2)" "unprognostic (1.39e-1)" "unprognostic (2.07e-1)" "unprognostic (1.92e-1)" "unprognostic (1.44e-1)" "unprognostic (2.07e-1)" "unprognostic (3.32e-1)" FLOT2 "ECS-1, ECS1, ESA, ESA1, M17S1" ENSG00000132589 "Flotillin 2" Q14254 17 28879335-28897733 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 353.8;Neutrophil progenitors: 335.2;Neutrophils: 1028.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001396, CAB004395, HPA071038" Supported Supported "Vesicles,Plasma membrane" NA NA 140000 "Cluster 21: Neutrophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 24: Neurons - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 24: Neutrophils - Innate immunity signal integration" 49 "Plasma membrane" Vesicles "CAB004395: , HPA001396: , HPA071038: " "unprognostic (3.02e-1)" "unprognostic (2.06e-1)" "unprognostic (3.69e-1)" "unprognostic (2.36e-3)" "unprognostic (7.53e-2)" "unprognostic (2.46e-2)" "unprognostic (2.62e-2)" "unprognostic (2.10e-1)" "unprognostic (3.09e-2)" "unprognostic (3.06e-1)" "potential prognostic favorable (2.58e-7)" "unprognostic (7.55e-2)" "unprognostic (2.41e-1)" "unprognostic (1.81e-3)" "potential prognostic unfavorable (1.14e-4)" "unprognostic (1.97e-1)" "unprognostic (1.70e-1)" "unprognostic (1.38e-1)" "unprognostic (2.23e-1)" "unprognostic (4.83e-2)" "unprognostic (4.62e-1)" "unprognostic (3.01e-2)" "unprognostic (2.39e-1)" "unprognostic (4.57e-2)" "unprognostic (1.11e-2)" "unprognostic (3.59e-2)" "unprognostic (1.45e-1)" "unprognostic (4.65e-2)" "unprognostic (2.02e-1)" "unprognostic (1.90e-1)" "unprognostic (1.64e-1)" FLRT1 "MGC21624, SPG68" ENSG00000126500 "Fibronectin leucine rich transmembrane protein 1" 11 64035931-64119173 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "adrenal gland: 4.1;brain: 6.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 55.7;Corticotrophs: 37.7;Epicardial cells: 15.9;Myonuclei: 70.2;Oligodendrocyte progenitor cells: 29.0;Retinal amacrine cells: 20.3;Schwann cells: 21.6" "Cell type enhanced" "Detected in many" "oligodendrocyte precursor cell: 36.5" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 4.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 5.6" "Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054589 Uncertain NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 55: Myocytes - Oxidative muscle function" 1 "HPA054589: " "unprognostic (5.73e-3)" "unprognostic (6.43e-2)" "unprognostic (2.15e-1)" "potential prognostic favorable (2.02e-4)" "unprognostic (5.27e-2)" "unprognostic (8.92e-3)" "unprognostic (3.01e-3)" "unprognostic (1.82e-1)" FLRT2 ENSG00000185070 "Fibronectin leucine rich transmembrane protein 2" O43155 14 85530144-85654428 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 38.6" "Cell type enhanced" "Detected in many" "Astrocytes: 429.8;Brain excitatory neurons: 312.1;Brain inhibitory neurons: 349.4;Choroid plexus epithelial cells: 888.2;Epicardial cells: 568.5;Fibro-adipogenic progenitors: 394.4;Leydig cells: 1098.7;Lymphatic endothelial cells: 402.2;Mesothelial cells: 968.9;Myonuclei: 852.8;Oligodendrocyte progenitor cells: 327.3;Pancreatic duct cells: 737.9;Peritubular myoid cells: 389.8;Retinal pigment epithelial cells: 788.6" "Cell type enhanced" "Detected in all" "fibroblast: 3299.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 27.1" "Adrenal gland - Adrenal cortex cells, Colon - Fibroblasts, Lung - Fibroblasts_2, Prostate - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" "Developmental protein" NA NA 19000 "Cluster 75: Ovary - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" "unprognostic (1.04e-1)" "unprognostic (2.07e-1)" "unprognostic (1.50e-2)" "unprognostic (4.30e-3)" "unprognostic (1.64e-1)" "unprognostic (4.20e-2)" "unprognostic (6.27e-2)" "unprognostic (2.00e-2)" "potential prognostic favorable (4.34e-4)" "unprognostic (1.72e-2)" "unprognostic (2.96e-1)" "unprognostic (1.17e-1)" "unprognostic (3.59e-2)" "unprognostic (6.84e-2)" "unprognostic (4.09e-1)" "unprognostic (1.80e-1)" "unprognostic (1.24e-1)" "unprognostic (1.72e-2)" "unprognostic (9.76e-3)" "unprognostic (8.23e-3)" "unprognostic (1.28e-1)" "unprognostic (9.88e-2)" FLRT3 ENSG00000125848 "Fibronectin leucine rich transmembrane protein 3" Q9NZU0 20 14322985-14337614 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cell adhesion" "Developmental protein" "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 21.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 359.6;Alveolar cells type 2: 214.0;Basal prostatic cells: 168.0;Epididymal basal cells: 85.4;Podocytes: 214.7;Transitional alveolar cells: 203.6" "Cell type enhanced" "Detected in all" "hippocampal dentate gyrus: 132.0" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 48.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Lung - Alveolar cells type 2, Prostate - Prostate basal glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056033 Enhanced Supported "Vesicles,Plasma membrane,Cell Junctions" "Intracellular and membrane" "Developmental protein" NA NA 210000 "Cluster 72: Kidney - Transmembrane transport" "Cluster 31: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 81: Alveolar cells - Lung function" 3 "Plasma membrane" "Vesicles, Cell Junctions" "HPA056033: " "unprognostic (3.38e-3)" "unprognostic (2.91e-1)" "unprognostic (1.88e-1)" "unprognostic (1.58e-1)" "unprognostic (2.67e-2)" "unprognostic (6.24e-2)" "unprognostic (3.42e-1)" "unprognostic (2.00e-1)" "unprognostic (3.83e-2)" "validated prognostic favorable (2.15e-10)" "validated prognostic favorable (4.93e-4)" "unprognostic (1.29e-3)" "unprognostic (2.84e-2)" "unprognostic (4.20e-2)" "unprognostic (2.31e-2)" "unprognostic (5.01e-3)" "potential prognostic unfavorable (1.33e-4)" "unprognostic (5.01e-2)" "unprognostic (5.80e-2)" "unprognostic (2.68e-1)" "potential prognostic unfavorable (4.11e-4)" "unprognostic (1.30e-3)" "unprognostic (1.88e-1)" "unprognostic (4.54e-2)" "unprognostic (1.92e-1)" "unprognostic (2.48e-1)" "unprognostic (3.25e-2)" "unprognostic (9.41e-2)" "unprognostic (6.36e-3)" "unprognostic (8.84e-3)" FLT1 "FLT, VEGFR1" ENSG00000102755 "Fms related receptor tyrosine kinase 1" P17948 13 28300346-28495145 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Chemotaxis, Differentiation" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "placenta: 394.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 308.8;Extravillous trophoblasts: 1644.7;Late spermatids: 279.5;Migrating cytotrophoblasts: 449.7;Müller glia: 545.6;Neutrophils: 284.2;Syncytiotrophoblasts: 1703.8;Vascular endothelial cells: 1218.5" "Cell type enriched" "Detected in many" 12 "endothelial cell: 3142.1" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 123.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 15.1;testis cancer: 39.8" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Pituitary gland - Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011740, HPA014290, CAB068189, CAB068190" Enhanced Supported "Plasma membrane,Actin filaments,Cytosol" "Secreted to blood" Receptor NA NA 876000 300000 "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 47: Endothelial cells - Vasculature" "Cluster 49: HMC-1 - Innate immune response" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 21 "Plasma membrane" "Actin filaments, Cytosol" "CAB068189: , CAB068190: , HPA011740: , HPA014290: " "unprognostic (1.82e-1)" "unprognostic (2.40e-2)" "unprognostic (2.03e-1)" "unprognostic (3.42e-3)" "unprognostic (4.86e-3)" "unprognostic (3.34e-2)" "unprognostic (2.12e-1)" "unprognostic (5.01e-3)" "unprognostic (6.22e-2)" "unprognostic (1.45e-1)" "validated prognostic favorable (2.61e-8)" "validated prognostic favorable (3.90e-4)" "unprognostic (1.78e-3)" "unprognostic (7.66e-2)" "unprognostic (1.43e-1)" "unprognostic (4.42e-3)" "unprognostic (9.15e-3)" "unprognostic (2.65e-3)" "unprognostic (2.15e-1)" "unprognostic (3.53e-1)" "potential prognostic unfavorable (8.13e-4)" "unprognostic (3.90e-1)" "unprognostic (2.96e-3)" "unprognostic (2.92e-1)" "unprognostic (1.41e-2)" "unprognostic (9.98e-2)" "unprognostic (4.56e-2)" "unprognostic (1.28e-2)" "unprognostic (6.21e-2)" "unprognostic (7.24e-2)" "unprognostic (6.25e-3)" FLT3 "CD135, FLK2, STK1" ENSG00000122025 "Fms related receptor tyrosine kinase 3" P36888 13 28003274-28100592 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, RAS pathway related proteins" "Host-virus interaction" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.0;brain: 8.9;lymphoid tissue: 6.1" "Cell type enhanced" "Detected in many" "cDC: 332.1;Hematopoietic stem cells: 850.1;Megakaryocyte-Erythroid progenitors: 150.0;Monocyte progenitors: 515.2;monocytes: 176.2;Neutrophils: 137.9;pDCs: 172.6;Thymocytes: 597.1" "Cell type enhanced" "Detected in many" "lower rhombic lip: 79.5;MGE interneuron: 94.6;upper rhombic lip: 84.5" "Cancer enhanced" "Detected in single" "Breast Invasive Carcinoma (TCGA): 2.5" "Region enhanced" "Detected in many" "cerebellum: 10.7" "Group enriched" "Detected in many" 13 "myeloid DC: 68.7;plasmacytoid DC: 26.3" "Lineage enriched" "Detected in many" 19 "dendritic cells: 68.7" "Cancer enriched" "Detected in single" 67 "Leukemia: 28.4" "Adrenal gland - Macrophages, Prostate - Macrophages, Spleen - Neutrophils_2, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA047539 Approved "Endoplasmic reticulum" NA NA 160000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 12 "Endoplasmic reticulum" "HPA047539: " "unprognostic (6.35e-3)" "unprognostic (1.19e-2)" "unprognostic (6.61e-2)" FLT3LG ENSG00000090554 "Fms related receptor tyrosine kinase 3 ligand" P49771 19 49474207-49486231 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 26.0;Fibroblasts: 8.7;Innate lymphoid cells: 10.0;Leydig cells: 9.0;Oocytes: 13.8;Ovarian stromal cells: 7.2;T-cells: 23.4" "Cell type enriched" "Detected in some" 4 "leukocyte: 9.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "gdT-cell: 77.9;MAIT T-cell: 144.7;memory CD4 T-cell: 158.7;memory CD8 T-cell: 102.0;naive CD4 T-cell: 170.1;naive CD8 T-cell: 138.2;T-reg: 171.5" "Lineage enriched" "Detected in all" 6 "T-cells: 171.5" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Prostate - Fibroblasts, Spleen - T-cells, Stomach - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted to blood" Cytokine NA NA 80000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" 1 "unprognostic (3.07e-3)" "unprognostic (1.07e-3)" "unprognostic (3.24e-2)" "unprognostic (1.10e-1)" "unprognostic (1.16e-2)" "unprognostic (2.48e-1)" "unprognostic (5.03e-2)" "unprognostic (2.92e-1)" "unprognostic (3.32e-3)" "unprognostic (5.44e-3)" "unprognostic (4.09e-3)" "unprognostic (1.56e-1)" "unprognostic (1.42e-1)" "unprognostic (2.28e-1)" "potential prognostic favorable (5.50e-4)" "unprognostic (1.11e-1)" "unprognostic (1.12e-1)" "unprognostic (2.62e-1)" "unprognostic (3.27e-1)" "unprognostic (9.11e-2)" "unprognostic (9.64e-2)" "unprognostic (3.48e-3)" "unprognostic (1.46e-1)" "unprognostic (3.79e-1)" "unprognostic (3.43e-1)" "unprognostic (2.84e-2)" "unprognostic (7.10e-2)" "unprognostic (7.21e-2)" "unprognostic (9.86e-2)" "unprognostic (2.16e-1)" "unprognostic (1.11e-2)" FLT4 "PCL, VEGFR-3, VEGFR3" ENSG00000037280 "Fms related receptor tyrosine kinase 4" P35916 5 180601506-180649624 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins, Transporters" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Extravillous trophoblasts: 104.1;Lymphatic endothelial cells: 197.0;Podocytes: 47.2;Undifferentiated spermatogonia: 14.2;Vascular endothelial cells: 32.4" "Cell type enriched" "Detected in some" 8 "endothelial cell: 32.6" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 20.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "MAIT T-cell: 3.8" "Lineage enriched" "Detected in single" 14 "T-cells: 3.8" "Low cancer specificity" "Detected in many" "Colon - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA067906, HPA074389" Approved Supported "Plasma membrane,Centrosome,Cytosol" "Secreted to blood" Receptor NA NA 20000000 43000000 "Cluster 1: T-cells - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 54: Non-specific - Transcription" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 24 Cytosol "Plasma membrane, Centrosome" "HPA067906: , HPA074389: " "unprognostic (4.13e-2)" "unprognostic (1.18e-1)" "unprognostic (7.15e-2)" "unprognostic (1.96e-1)" "unprognostic (1.14e-2)" "unprognostic (7.99e-2)" "unprognostic (5.76e-2)" "unprognostic (1.29e-1)" "unprognostic (3.46e-2)" "unprognostic (2.09e-2)" "validated prognostic favorable (5.61e-6)" "validated prognostic favorable (8.45e-5)" "unprognostic (8.98e-2)" "unprognostic (4.80e-2)" "potential prognostic favorable (2.55e-4)" "unprognostic (1.80e-1)" "unprognostic (1.98e-2)" "potential prognostic unfavorable (9.96e-4)" "unprognostic (6.93e-2)" "unprognostic (2.98e-2)" "unprognostic (1.34e-1)" "unprognostic (9.09e-3)" "unprognostic (4.82e-2)" "unprognostic (9.24e-2)" "unprognostic (7.37e-2)" "unprognostic (6.89e-3)" "unprognostic (1.65e-1)" "unprognostic (1.52e-2)" "unprognostic (1.73e-1)" "unprognostic (1.09e-1)" "unprognostic (4.47e-2)" FLVCR1 "AXPC1, FLVCR, MFSD7B, PCA, SLC49A1" ENSG00000162769 "FLVCR heme transporter 1" Q9Y5Y0 1 212858275-212899363 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Erythrocyte maturation, Transport" Receptor "Disease variant, Epilepsy, Intellectual disability, Neurodegeneration, Neuropathy, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 18.2" "Cell type enhanced" "Detected in many" "Enterocytes: 114.3;Gonadotrophs: 123.6;Neutrophil progenitors: 147.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046646 Approved Approved "Cell Junctions" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 14 "Cell Junctions" "HPA046646: " "unprognostic (4.48e-2)" "unprognostic (1.10e-1)" "unprognostic (2.67e-1)" "unprognostic (7.80e-2)" "unprognostic (1.98e-2)" "unprognostic (3.69e-1)" "unprognostic (2.12e-1)" "unprognostic (3.09e-3)" "unprognostic (2.45e-1)" "unprognostic (1.92e-2)" "unprognostic (5.28e-2)" "unprognostic (3.44e-2)" "unprognostic (2.57e-2)" "validated prognostic unfavorable (1.64e-5)" "validated prognostic unfavorable (1.42e-5)" "unprognostic (1.24e-1)" "unprognostic (1.64e-1)" "unprognostic (8.17e-2)" "unprognostic (3.28e-3)" "unprognostic (2.88e-1)" "unprognostic (1.70e-2)" "potential prognostic favorable (1.65e-4)" "unprognostic (2.59e-1)" "unprognostic (2.91e-1)" "unprognostic (1.41e-1)" "unprognostic (2.19e-1)" "unprognostic (4.59e-2)" "unprognostic (3.38e-1)" "unprognostic (2.04e-1)" "unprognostic (1.10e-2)" "unprognostic (3.76e-1)" FLVCR2 "C14orf58, CCT, FLJ20371, MFSD7C, SLC49A2" ENSG00000119686 "FLVCR heme transporter 2" Q9UPI3 14 75578620-75663214 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 28.5" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 139.8;Enterocytes: 118.9;Kupffer cells: 191.7;Macrophages: 67.1;monocytes: 81.6;Proximal tubule cells: 72.8;Renal collecting duct intercalated cells: 82.2;Retinal pigment epithelial cells: 370.9;Sertoli cells: 88.2" "Group enriched" "Detected in many" 7 "choroid plexus epithelial cell: 113.7;endothelial cell: 167.0;fibroblast: 391.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 14.1;intermediate monocyte: 14.6;myeloid DC: 7.6;non-classical monocyte: 11.9" "Group enriched" "Detected in many" 7 "dendritic cells: 7.6;monocytes: 14.6" "Low cancer specificity" "Detected in many" "Adipose visceral - Macrophages, Lung - Macrophages, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037984 Enhanced NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 8: Immune cells - Immune response" "Cluster 34: Testis cancer - Unknown function" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 1 "HPA037984: " "unprognostic (6.67e-2)" "unprognostic (1.66e-1)" "unprognostic (7.44e-2)" "unprognostic (1.76e-1)" "unprognostic (2.43e-1)" "unprognostic (1.69e-1)" "unprognostic (1.17e-1)" "unprognostic (2.77e-1)" "unprognostic (6.82e-2)" "unprognostic (1.53e-2)" "potential prognostic favorable (9.52e-6)" "unprognostic (4.02e-2)" "unprognostic (1.01e-3)" "unprognostic (2.05e-2)" "unprognostic (1.31e-3)" "unprognostic (2.25e-1)" "unprognostic (7.58e-3)" "unprognostic (1.08e-1)" "unprognostic (7.23e-2)" "unprognostic (1.39e-1)" "unprognostic (1.69e-1)" "unprognostic (1.55e-1)" "unprognostic (7.62e-3)" "unprognostic (2.43e-1)" "unprognostic (3.10e-2)" "unprognostic (1.60e-1)" "unprognostic (2.15e-1)" "unprognostic (8.85e-2)" "unprognostic (8.55e-2)" "unprognostic (7.12e-3)" "unprognostic (8.04e-2)" FLYWCH1 DKFZp761A132 ENSG00000059122 "FLYWCH-type zinc finger 1" Q4VC44 16 2911931-2951208 "Predicted intracellular proteins" "DNA damage, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 93.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040753, HPA041001" Approved Enhanced "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 24: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 9 "Nucleoplasm, Nuclear bodies" Cytosol "HPA040753: , HPA041001: " "unprognostic (3.97e-1)" "unprognostic (4.06e-2)" "unprognostic (5.38e-2)" "unprognostic (3.21e-2)" "unprognostic (5.66e-2)" "unprognostic (1.23e-1)" "unprognostic (2.11e-1)" "unprognostic (1.28e-2)" "unprognostic (7.57e-2)" "unprognostic (2.91e-1)" "potential prognostic favorable (2.57e-4)" "unprognostic (7.95e-2)" "unprognostic (3.86e-2)" "unprognostic (3.23e-3)" "unprognostic (1.54e-1)" "unprognostic (1.39e-1)" "unprognostic (1.12e-1)" "unprognostic (1.58e-1)" "unprognostic (1.82e-1)" "unprognostic (1.47e-1)" "unprognostic (2.12e-1)" "unprognostic (2.56e-2)" "unprognostic (2.73e-2)" "unprognostic (1.10e-1)" "unprognostic (1.28e-2)" "unprognostic (3.33e-2)" "unprognostic (1.55e-1)" "unprognostic (1.14e-2)" "unprognostic (1.40e-1)" "unprognostic (2.33e-3)" "unprognostic (4.99e-2)" FLYWCH2 ENSG00000162076 "FLYWCH family member 2" Q96CP2 16 2883213-2899382 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 138.8;Oocytes: 188.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041354 Uncertain Approved Nucleoplasm NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 5: Spleen - Immune response" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 54: Non-specific - Transcription" "Cluster 41: Oocytes - Oogenesis" 9 Nucleoplasm "HPA041354: " "unprognostic (8.28e-2)" "unprognostic (3.86e-2)" "unprognostic (1.30e-1)" "unprognostic (1.14e-2)" "unprognostic (1.24e-1)" "unprognostic (4.20e-2)" "unprognostic (3.21e-2)" "unprognostic (6.90e-2)" "unprognostic (2.74e-1)" "unprognostic (8.62e-3)" "unprognostic (2.66e-1)" "unprognostic (1.25e-2)" "unprognostic (1.16e-1)" "validated prognostic unfavorable (1.81e-4)" "validated prognostic unfavorable (1.49e-5)" "unprognostic (1.79e-1)" "unprognostic (1.31e-1)" "unprognostic (1.87e-1)" "unprognostic (1.06e-1)" "unprognostic (1.25e-1)" "unprognostic (2.88e-2)" "potential prognostic favorable (4.51e-6)" "unprognostic (2.88e-1)" "unprognostic (5.69e-2)" "unprognostic (2.09e-2)" "unprognostic (3.49e-1)" "unprognostic (1.68e-1)" "unprognostic (2.18e-1)" "unprognostic (1.04e-1)" "unprognostic (7.68e-2)" "unprognostic (2.88e-2)" FMC1 "C7orf55, HSPC268" ENSG00000164898 "Formation of mitochondrial complex V assembly factor 1 homolog" Q96HJ9 7 139339457-139346328 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Late primary spermatocytes: 559.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045663, HPA050553" Approved Approved Mitochondria NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 52: Non-specific - Cellular respiration" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 5 Mitochondria "HPA045663: , HPA050553: " "unprognostic (1.48e-1)" "unprognostic (1.21e-1)" "potential prognostic favorable (4.43e-4)" "unprognostic (6.82e-2)" "unprognostic (2.39e-2)" "unprognostic (8.10e-2)" "unprognostic (1.29e-1)" "unprognostic (8.59e-2)" "unprognostic (2.56e-1)" "unprognostic (1.69e-2)" "unprognostic (1.19e-1)" "potential prognostic favorable (3.40e-4)" "unprognostic (6.35e-2)" "unprognostic (1.79e-2)" "unprognostic (1.90e-1)" "unprognostic (5.75e-3)" "unprognostic (1.27e-2)" "potential prognostic favorable (5.39e-5)" "unprognostic (2.21e-1)" "unprognostic (1.24e-3)" "unprognostic (1.91e-2)" "unprognostic (9.35e-2)" "unprognostic (1.66e-1)" "unprognostic (8.99e-3)" "unprognostic (2.27e-3)" "unprognostic (3.18e-1)" "unprognostic (2.78e-2)" "unprognostic (1.90e-1)" "unprognostic (8.47e-2)" FMC1-LUC7L2 C7orf55-LUC7L2 ENSG00000269955 "FMC1-LUC7L2 readthrough" 7 139341360-139422599 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA045663, HPA051631" Approved Approved Nucleoplasm NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 24: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 39: Non-specific - Transcription" Nucleoplasm "HPA045663: , HPA051631: " "unprognostic (9.86e-2)" "unprognostic (1.04e-1)" "unprognostic (6.00e-2)" "unprognostic (2.87e-1)" "unprognostic (2.89e-2)" "unprognostic (1.36e-1)" "unprognostic (4.68e-2)" "unprognostic (9.91e-3)" "potential prognostic favorable (6.34e-9)" "unprognostic (2.39e-2)" "unprognostic (4.91e-2)" "unprognostic (1.44e-1)" "unprognostic (5.36e-2)" "unprognostic (6.02e-2)" "unprognostic (1.71e-1)" "unprognostic (1.44e-2)" "unprognostic (4.41e-1)" "unprognostic (8.40e-2)" "unprognostic (9.70e-2)" "unprognostic (1.39e-1)" "unprognostic (1.25e-2)" "unprognostic (2.44e-2)" "unprognostic (1.05e-1)" "unprognostic (4.21e-2)" "unprognostic (7.35e-2)" "unprognostic (1.58e-1)" FMN1 "DKFZP686C2281, FLJ45135, FMN, LD, MGC125288, MGC125289" ENSG00000248905 "Formin 1" Q68DA7 15 32765544-33194714 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 27.8" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 1531.9;Distal convoluted tubule cells: 817.3;Lactotrophs: 412.1;Macrophages: 547.7;Melanocytes: 970.4;Microglia: 316.0;monocytes: 500.9;Retinal bipolar cells: 702.3;Retinal ganglion cells: 332.2;Rod photoreceptor cells: 358.9" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 9 "Skin Cutaneous Melanoma (TCGA): 52.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in many" 5 "skin cancer: 45.6" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Heart muscle - Macrophages, Pituitary gland - Lactotropes, Stomach - Gastric mucous cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005465, HPA046786" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 42: Retina - Visual perception" "Cluster 53: Neurons - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" Nucleoplasm Cytosol "HPA005465: , HPA046786: " "unprognostic (1.93e-1)" "unprognostic (7.76e-2)" "unprognostic (5.67e-2)" "unprognostic (1.49e-2)" "unprognostic (7.99e-2)" "unprognostic (1.30e-2)" "unprognostic (5.18e-2)" "unprognostic (1.82e-2)" "unprognostic (5.03e-3)" "unprognostic (7.08e-2)" "unprognostic (8.11e-2)" "unprognostic (3.58e-1)" "unprognostic (2.65e-2)" "unprognostic (6.20e-3)" "unprognostic (2.66e-3)" "unprognostic (2.70e-3)" "unprognostic (9.74e-3)" "unprognostic (4.12e-2)" "potential prognostic unfavorable (8.16e-4)" "unprognostic (5.46e-3)" "unprognostic (1.04e-1)" "unprognostic (1.69e-1)" "unprognostic (1.28e-1)" "unprognostic (1.16e-1)" "unprognostic (1.85e-1)" "unprognostic (5.47e-1)" "unprognostic (9.81e-2)" "unprognostic (4.22e-3)" FMN2 ENSG00000155816 "Formin 2" Q9NZ56 1 240014348-240475187 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, Protein transport, Stress response, Transport" "Actin-binding, Developmental protein" "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.0;parathyroid gland: 18.5;retina: 15.4" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 531.8;Astrocytes: 1312.2;Bergmann glia: 1387.5;Brain excitatory neurons: 443.0;Brain inhibitory neurons: 428.2;Cone photoreceptor cells: 546.5;Ependymal cells: 798.7;Lactotrophs: 507.7;Podocytes: 1883.6;Retinal amacrine cells: 476.2;Retinal horizontal cells: 1799.0;Somatotrophs: 553.5;Thyrotrophs: 824.0" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in some" 8 "Glioblastoma Multiforme (TCGA): 24.5;Testicular Germ Cell Tumor (TCGA): 10.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 20.6" "Adipose visceral - Mesothelial cells, Kidney - Podocytes, Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Pancreas - Beta cells, Pituitary gland - Thyrotropes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" HPA050649 Supported "Plasma membrane,Actin filaments" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 28: Astrocytes - Homeostasis & neuron support" 9 "Actin filaments" "Plasma membrane" "HPA050649: " "unprognostic (3.98e-2)" "unprognostic (1.20e-1)" "unprognostic (6.75e-2)" "unprognostic (3.59e-3)" "unprognostic (4.22e-2)" "unprognostic (3.82e-1)" "unprognostic (1.79e-1)" "unprognostic (2.03e-3)" FMNL1 "C17orf1, C17orf1B, FMNL" ENSG00000184922 "Formin like 1" O95466 17 45221444-45247319 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 255.3;lymphoid tissue: 101.4" "Cell type enriched" "Detected in many" 4 "Neutrophils: 834.5" "Group enriched" "Detected in many" 4 "central nervous system macrophage: 93.8;leukocyte: 150.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Adrenocortical cancer: 84.6;Leukemia: 67.7;lymphoma: 77.0;Myeloma: 116.9" "Breast - T-cells, Kidney - T-cells, Prostate - T-cells, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008129, HPA028288" Enhanced Approved Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 7 Cytosol "HPA008129: , HPA028288: " "unprognostic (3.81e-2)" "unprognostic (3.82e-3)" "potential prognostic favorable (2.48e-4)" "unprognostic (1.97e-1)" "unprognostic (3.55e-2)" "unprognostic (2.37e-1)" "unprognostic (6.16e-2)" "unprognostic (8.17e-2)" "unprognostic (1.47e-2)" "unprognostic (5.09e-2)" "potential prognostic unfavorable (4.12e-4)" "unprognostic (5.29e-2)" "unprognostic (4.24e-2)" "unprognostic (1.32e-1)" "unprognostic (7.97e-2)" "unprognostic (1.02e-1)" "unprognostic (1.67e-1)" "unprognostic (5.61e-2)" "unprognostic (1.36e-1)" "unprognostic (1.76e-2)" "unprognostic (2.46e-1)" "unprognostic (2.63e-1)" "potential prognostic unfavorable (7.77e-4)" "unprognostic (3.11e-1)" "unprognostic (2.37e-2)" "unprognostic (8.19e-2)" "unprognostic (2.15e-2)" "unprognostic (1.14e-1)" "unprognostic (5.05e-2)" "unprognostic (3.34e-2)" "unprognostic (2.98e-2)" FMNL2 "FHOD2, KIAA1902" ENSG00000157827 "Formin like 2" Q96PY5 2 152335174-152649826 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 214.1" "Cell type enhanced" "Detected in many" "Astrocytes: 1032.3;Choroid plexus epithelial cells: 1055.3;Kupffer cells: 1302.7;Myonuclei: 904.3;Oligodendrocytes: 2683.0;Pituicytes/FSCs: 969.0;Pituitary stem cells: 929.1" "Cell type enhanced" "Detected in all" "oligodendrocyte: 4194.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.2" "Lineage enriched" "Detected in single" 5 "monocytes: 1.2" "Low cancer specificity" "Detected in all" "Skin - Endothelial cells, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005464 Enhanced Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA 6500000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 69: Skin cancer - ECM organization" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 15 Cytosol "Golgi apparatus, Plasma membrane" "HPA005464: " "unprognostic (1.21e-1)" "unprognostic (1.21e-1)" "unprognostic (1.24e-2)" "unprognostic (1.87e-1)" "unprognostic (2.10e-1)" "unprognostic (2.03e-1)" "unprognostic (1.26e-2)" "unprognostic (1.97e-1)" "unprognostic (8.83e-2)" "unprognostic (1.26e-3)" "unprognostic (1.67e-1)" "unprognostic (1.58e-1)" "unprognostic (4.07e-2)" "unprognostic (1.26e-3)" "unprognostic (1.26e-1)" "unprognostic (3.47e-2)" "unprognostic (3.32e-2)" "unprognostic (3.48e-1)" "unprognostic (9.04e-3)" "unprognostic (2.40e-1)" "unprognostic (4.56e-2)" "unprognostic (1.90e-1)" "unprognostic (1.27e-3)" "unprognostic (6.30e-2)" "unprognostic (2.31e-2)" "unprognostic (2.55e-3)" "unprognostic (7.82e-2)" "unprognostic (1.07e-1)" "unprognostic (1.50e-1)" "unprognostic (3.07e-2)" "unprognostic (2.44e-2)" FMNL3 "DKFZp762B245, MGC45819, WBP3" ENSG00000161791 "Formin like 3" Q8IVF7 12 49636499-49708165 "Predicted intracellular proteins" Angiogenesis "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Microglia: 566.6" "Group enriched" "Detected in all" 5 "central nervous system macrophage: 695.8;endothelial cell: 316.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 5.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Colon - Enteric glia cells, Liver - Vascular endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002552, HPA023201" Uncertain Supported "Golgi apparatus,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 2 "Golgi apparatus, Vesicles, Plasma membrane" Cytosol "HPA002552: , HPA023201: " "unprognostic (1.38e-1)" "unprognostic (1.05e-1)" "unprognostic (3.44e-1)" "unprognostic (2.68e-1)" "unprognostic (5.67e-2)" "unprognostic (3.74e-2)" "unprognostic (1.39e-1)" "unprognostic (3.78e-2)" "unprognostic (4.09e-3)" "unprognostic (1.13e-3)" "validated prognostic favorable (3.50e-4)" "validated prognostic favorable (6.55e-4)" "unprognostic (1.24e-1)" "unprognostic (1.64e-2)" "unprognostic (8.82e-2)" "unprognostic (3.85e-3)" "unprognostic (1.16e-2)" "unprognostic (3.01e-1)" "unprognostic (3.39e-1)" "unprognostic (1.59e-2)" "unprognostic (1.12e-3)" "unprognostic (2.99e-1)" "unprognostic (1.06e-1)" "unprognostic (2.23e-1)" "unprognostic (4.42e-1)" "unprognostic (1.11e-3)" "unprognostic (3.00e-1)" "unprognostic (6.47e-2)" "unprognostic (1.00e-1)" "unprognostic (4.40e-1)" "unprognostic (2.20e-1)" FMO1 ENSG00000010932 "Flavin containing dimethylaniline monoxygenase 1" Q01740 1 171248471-171285978 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "kidney: 185.7" "Cell type enhanced" "Detected in some" "Enterocytes: 127.0;Granulosa cells: 25.1;Mesothelial cells: 31.9;Ocular epithelial cells: 60.6;Pituitary stem cells: 31.2;Proximal tubule cells: 89.5;Salivary ionocytes: 138.6" "Group enriched" "Detected in some" 6 "choroid plexus epithelial cell: 5.1;fibroblast: 4.0;pericyte: 4.4" "Group enriched" "Detected in many" 8 "Kidney Renal Clear Cell Carcinoma (TCGA): 43.1;Kidney Renal Papillary Cell Carcinoma (TCGA): 48.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Rhabdoid: 1.4" "Breast - T-cells, Kidney - Proximal tubular cells, Lung - Fibroblasts_2, Pituitary gland - Fibroblasts, Skeletal muscle - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078132 Approved NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 100: Stratified epithelial cells - Barrier functions" 5 "HPA078132: " "unprognostic (1.59e-1)" "unprognostic (2.40e-1)" "unprognostic (8.62e-2)" "unprognostic (2.93e-2)" "unprognostic (1.30e-2)" "unprognostic (5.73e-2)" "potential prognostic favorable (2.83e-9)" "unprognostic (5.04e-3)" "unprognostic (1.04e-2)" "unprognostic (1.55e-1)" "unprognostic (1.59e-1)" "unprognostic (9.14e-2)" "unprognostic (3.54e-3)" "unprognostic (6.34e-2)" "unprognostic (1.77e-1)" "unprognostic (3.62e-2)" "potential prognostic unfavorable (4.11e-4)" "unprognostic (1.99e-2)" "unprognostic (6.46e-2)" "unprognostic (3.29e-1)" "potential prognostic unfavorable (4.67e-4)" "unprognostic (2.74e-1)" FMO2 ENSG00000094963 "Flavin containing dimethylaniline monoxygenase 2" Q99518 1 171185249-171212686 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 65.4;blood vessel: 93.7;lung: 74.8" "Cell type enriched" "Detected in many" 5 "Esophageal apical cells: 1175.5" "Cell type enriched" "Detected in some" 16 "fibroblast: 361.2" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 14.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Fibroblasts, Lung - Fibroblasts_1, Pancreas - Fibroblasts, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028261 Approved NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" "HPA028261: " "unprognostic (3.56e-2)" "unprognostic (2.09e-1)" "unprognostic (1.04e-1)" "unprognostic (6.98e-2)" "unprognostic (5.42e-2)" "potential prognostic favorable (6.90e-5)" "unprognostic (4.06e-3)" "unprognostic (8.28e-3)" "potential prognostic favorable (1.72e-5)" "unprognostic (6.08e-3)" "unprognostic (8.87e-2)" "unprognostic (1.35e-1)" "unprognostic (9.42e-2)" "validated prognostic unfavorable (2.94e-4)" "validated prognostic unfavorable (3.65e-4)" "unprognostic (2.59e-1)" "unprognostic (4.90e-2)" "unprognostic (3.97e-1)" "unprognostic (2.28e-1)" "potential prognostic unfavorable (7.84e-4)" "unprognostic (2.10e-1)" FMO3 FMOII ENSG00000007933 "Flavin containing dimethylaniline monoxygenase 3" P31513 1 171090901-171117819 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 40 "liver: 1050.2" "Cell type enriched" "Detected in some" 12 "Hepatocytes: 600.5" "Group enriched" "Detected in some" 4 "ependymal cell: 26.7;fibroblast: 18.1;oligodendrocyte precursor cell: 22.5;pericyte: 37.4" "Cancer enriched" "Detected in many" 8 "Liver Hepatocellular Carcinoma (TCGA): 198.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 3.1;Myeloma: 2.1" "Adrenal gland - Fibroblasts, Colon - Endothelial cells, Liver - Hepatocytes, Lung - Fibroblasts_1, Spleen - Fibroblasts_2" "Not detected" "Not detected" "Not detected" "Not detected" HPA013750 Enhanced NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 43: Hindbrain - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 93: Hepatocytes - Bile production & excretion" 3 "HPA013750: " "unprognostic (1.96e-1)" "unprognostic (9.83e-2)" "unprognostic (1.26e-2)" "potential prognostic favorable (8.14e-4)" "unprognostic (3.60e-2)" "unprognostic (3.88e-1)" "unprognostic (7.20e-2)" "unprognostic (3.67e-3)" "unprognostic (1.18e-1)" "unprognostic (3.45e-2)" "unprognostic (3.42e-3)" "unprognostic (7.08e-2)" "validated prognostic favorable (3.41e-4)" "validated prognostic favorable (5.25e-4)" "potential prognostic favorable (8.24e-4)" "unprognostic (9.56e-2)" "unprognostic (2.00e-2)" "unprognostic (4.35e-2)" "unprognostic (6.22e-2)" "unprognostic (1.47e-3)" "unprognostic (1.65e-1)" "unprognostic (1.32e-1)" "unprognostic (1.73e-1)" "unprognostic (1.38e-1)" "unprognostic (1.39e-1)" "unprognostic (2.39e-1)" "unprognostic (2.71e-1)" "unprognostic (2.24e-1)" FMO4 FMO2 ENSG00000076258 "Flavin containing dimethylaniline monoxygenase 4" P31512 1 171314183-171342084 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "kidney: 45.3;liver: 57.3" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 94.2;Enterocytes: 68.5;Hepatocytes: 51.6;Proximal tubule cells: 120.9;Renal connecting tubule cells: 74.0" "Cell type enhanced" "Detected in many" "fibroblast: 30.6;oligodendrocyte: 35.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Thyroid gland - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA049100, HPA072438" Approved Approved Vesicles,Cytosol NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 30: White matter - Myelination" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 88: Proximal tubular cells - Transmembrane transport" "Vesicles, Cytosol" "HPA049100: , HPA072438: " "unprognostic (4.95e-2)" "unprognostic (3.76e-2)" "unprognostic (1.63e-1)" "unprognostic (1.68e-1)" "unprognostic (1.21e-1)" "unprognostic (2.25e-1)" "unprognostic (3.90e-2)" "unprognostic (2.06e-2)" "unprognostic (2.95e-1)" "unprognostic (2.00e-1)" "potential prognostic favorable (3.04e-6)" "unprognostic (8.38e-3)" "potential prognostic favorable (3.90e-5)" "validated prognostic favorable (6.27e-4)" "validated prognostic favorable (4.75e-8)" "unprognostic (1.37e-3)" "unprognostic (4.77e-2)" "unprognostic (6.17e-2)" "unprognostic (1.07e-1)" "unprognostic (1.68e-1)" "unprognostic (2.76e-3)" "unprognostic (8.72e-2)" "unprognostic (2.86e-1)" "unprognostic (1.88e-1)" "unprognostic (3.19e-1)" "unprognostic (7.86e-2)" "unprognostic (2.23e-1)" "unprognostic (3.95e-2)" "unprognostic (1.61e-1)" "unprognostic (2.87e-1)" "unprognostic (1.33e-1)" FMO5 ENSG00000131781 "Flavin containing dimethylaniline monoxygenase 5" P49326 1 147175351-147243050 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 638.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 234.4;Cardiomyocytes: 237.9;Cholangiocytes: 220.6;Enterocytes: 163.2;Gastric chief cells: 214.0;Hepatocytes: 434.2;Lacrimal acinar cells: 152.2" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Liver Hepatocellular Carcinoma (TCGA): 158.3;Lung Adenocarcinoma (TCGA): 41.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "liver cancer: 9.0" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Liver - Hepatocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Skin - Eccrine sweat gland cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012373 Enhanced Supported "Endoplasmic reticulum,Cytosol" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 30: White matter - Myelination" "Cluster 18: Liver cancer - Metabolism" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" "Endoplasmic reticulum, Cytosol" "HPA012373: " "unprognostic (3.90e-2)" "unprognostic (2.61e-1)" "unprognostic (1.41e-2)" "unprognostic (8.89e-2)" "unprognostic (4.56e-2)" "unprognostic (1.69e-1)" "unprognostic (4.00e-2)" "unprognostic (3.19e-2)" "unprognostic (2.89e-2)" "potential prognostic favorable (3.67e-4)" "unprognostic (2.00e-2)" "potential prognostic favorable (6.75e-4)" "unprognostic (9.38e-2)" "unprognostic (1.14e-1)" "unprognostic (1.07e-2)" "unprognostic (3.71e-1)" "unprognostic (1.20e-2)" "unprognostic (3.41e-2)" "unprognostic (1.62e-1)" "unprognostic (6.44e-2)" "unprognostic (3.21e-1)" "unprognostic (3.07e-2)" "unprognostic (1.08e-1)" "unprognostic (4.06e-1)" "potential prognostic unfavorable (2.53e-4)" "unprognostic (4.11e-2)" "unprognostic (7.98e-2)" "unprognostic (2.32e-1)" "unprognostic (1.10e-1)" "unprognostic (1.14e-2)" FMOD SLRR2E ENSG00000122176 Fibromodulin Q06828 1 203340628-203351758 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 432.3" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 49.9;Decidual stromal cells: 47.5;Fibroblasts: 69.0;Gastric chief cells: 168.2;Goblet cells: 78.4;Hepatic stellate cells: 109.7;Lymphatic endothelial cells: 64.7;Mucous neck cells: 148.4;Ovarian stromal cells: 50.4;Parietal cells: 46.0" "Cell type enriched" "Detected in some" 9 "fibroblast: 136.2" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "choroid plexus: 17.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "breast cancer: 43.2;skin cancer: 19.0;thyroid cancer: 17.1" "Adrenal gland - Fibroblasts, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Fibroblasts, Prostate - Fibroblasts, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 94.0" "Secreted to extracellular matrix" "No annotated function" NA NA 1200000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 8: Immune cells - Immune response" "Cluster 27: Breast cancer - Unknown function" "Cluster 108: Fibroblasts - ECM organization" 20 "unprognostic (4.15e-2)" "unprognostic (1.46e-1)" "unprognostic (6.14e-2)" "unprognostic (2.94e-2)" "unprognostic (2.63e-1)" "potential prognostic unfavorable (7.04e-4)" "unprognostic (8.86e-3)" "potential prognostic unfavorable (2.05e-6)" "unprognostic (1.89e-2)" "unprognostic (9.20e-2)" "unprognostic (2.47e-2)" "unprognostic (1.08e-1)" "unprognostic (4.65e-2)" "unprognostic (2.12e-1)" "unprognostic (1.90e-1)" "unprognostic (6.77e-2)" "unprognostic (1.60e-2)" "unprognostic (1.36e-2)" "unprognostic (1.06e-1)" "unprognostic (2.83e-2)" "unprognostic (1.98e-2)" "unprognostic (6.20e-3)" "unprognostic (5.48e-3)" "unprognostic (1.70e-1)" "unprognostic (6.87e-2)" "unprognostic (9.90e-2)" "potential prognostic unfavorable (2.66e-5)" "unprognostic (1.45e-2)" "unprognostic (3.38e-2)" "potential prognostic unfavorable (2.74e-4)" "unprognostic (5.47e-2)" FMR1 "FMRP, FRAXA, MGC87458, POF, POF1" ENSG00000102081 "Fragile X messenger ribonucleoprotein 1" Q06787 X 147911919-147951125 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, Host-virus interaction, mRNA processing, mRNA splicing, mRNA transport, Neurogenesis, RNA-mediated gene silencing, Translation regulation, Transport" "Activator, Repressor, Ribonucleoprotein, RNA-binding" "Disease variant, Intellectual disability, Neurodegeneration, Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012444, HPA050118, HPA056084" Approved Enhanced Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 22: Epididymis - Mixed function" "Cluster 55: Non-specific - Transcription" "Cluster 36: Non-specific - mRNA processing" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 81 Cytosol "CAB012444: , HPA050118: , HPA056084: " "unprognostic (1.63e-1)" "unprognostic (1.79e-2)" "unprognostic (7.53e-2)" "unprognostic (1.02e-1)" "unprognostic (1.11e-1)" "unprognostic (1.72e-1)" "unprognostic (9.71e-2)" "unprognostic (3.39e-2)" "unprognostic (2.29e-1)" "unprognostic (5.37e-2)" "potential prognostic favorable (1.09e-5)" "unprognostic (1.14e-1)" "unprognostic (1.26e-1)" "unprognostic (4.07e-1)" "unprognostic (3.74e-1)" "unprognostic (2.59e-1)" "unprognostic (1.33e-1)" "unprognostic (3.40e-2)" "unprognostic (5.00e-2)" "unprognostic (4.75e-2)" "unprognostic (3.17e-1)" "unprognostic (1.16e-2)" "unprognostic (1.54e-2)" "unprognostic (1.33e-2)" "unprognostic (9.36e-3)" "unprognostic (6.97e-3)" "unprognostic (1.39e-1)" "unprognostic (3.11e-2)" "unprognostic (2.29e-1)" "unprognostic (4.10e-2)" "unprognostic (1.91e-1)" FMR1NB "CT37, FLJ25736, NY-SAR-35" ENSG00000176988 "FMR1 neighbor" Q8N0W7 X 147981337-148026665 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 344 "testis: 56.7" "Group enriched" "Detected in some" 7 "Differentiating spermatogonia: 293.6;Early primary spermatocytes: 648.3" "Low cell type specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "Bile duct cancer: 41.4;Myeloma: 11.8" "Testis - Spermatocytes" "Not detected" "Not detected" "HPA011284, CAB026403" Enhanced Approved Acrosome NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 3: Early primary spermatocytes - Early meiosis" 1 Acrosome "CAB026403: , HPA011284: " FN1 "CIG, FINC, GFND2, LETS, MSF" ENSG00000115414 "Fibronectin 1" P02751 2 215360440-215436073 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase, Angiogenesis, Cell adhesion, Cell shape" Heparin-binding "Cancer-related genes, Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 2745.6;liver: 1614.4;placenta: 2751.7" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 5994.2;Fibroblasts: 583.9;Hepatic stellate cells: 1658.9;Hepatocytes: 1505.4;Medullary thymic epithelial cells: 952.9;Migrating cytotrophoblasts: 1440.3;Smooth muscle cells: 1068.6;Vascular smooth muscle cells: 585.6" "Cell type enhanced" "Detected in all" "endothelial cell: 716.1;pericyte: 1227.5" "Cancer enhanced" "Detected in all" "Thyroid Carcinoma (TCGA): 3346.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "testis cancer: 4284.8;thyroid cancer: 4456.7" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Prostate - Smooth muscle cells, Skeletal muscle - Fibroblasts, Spleen - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000126, HPA027066" Enhanced "Secreted to blood" "Acute phase" NA NA 227000000000 84000000000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 12: Non-specific - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 59 "CAB000126: , HPA027066: " "unprognostic (2.38e-1)" "unprognostic (2.13e-1)" "unprognostic (1.37e-1)" "potential prognostic unfavorable (8.26e-4)" "unprognostic (2.89e-2)" "unprognostic (2.20e-1)" "unprognostic (9.78e-3)" "unprognostic (1.79e-1)" "unprognostic (1.47e-2)" "unprognostic (1.55e-2)" "unprognostic (2.80e-2)" "unprognostic (1.21e-2)" "potential prognostic unfavorable (4.98e-7)" "unprognostic (9.55e-2)" "unprognostic (1.63e-1)" "unprognostic (5.30e-2)" "unprognostic (1.32e-3)" "unprognostic (7.42e-3)" "unprognostic (9.45e-3)" "potential prognostic unfavorable (3.40e-4)" "unprognostic (7.71e-3)" "unprognostic (1.43e-2)" "unprognostic (1.17e-1)" "unprognostic (4.05e-1)" "unprognostic (3.47e-1)" "unprognostic (9.78e-3)" "unprognostic (1.01e-1)" "potential prognostic unfavorable (3.60e-4)" "unprognostic (8.07e-2)" "unprognostic (1.85e-1)" "unprognostic (3.75e-2)" FN3K ENSG00000167363 "Fructosamine 3 kinase" Q9H479 17 82735615-82751196 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubule cells: 73.1;Retinal ganglion cells: 88.8;Somatotrophs: 102.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059151, HPA061358" Supported Enhanced Mitochondria NA NA 300000 "Cluster 76: Non-specific - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 103: Non-specific - Basic cellular processes" 2 Mitochondria "HPA059151: , HPA061358: " "unprognostic (2.15e-2)" "unprognostic (2.56e-1)" "unprognostic (7.55e-2)" "unprognostic (9.19e-2)" "unprognostic (2.16e-2)" "unprognostic (1.50e-2)" "unprognostic (4.29e-2)" "unprognostic (4.67e-3)" "unprognostic (8.74e-2)" "unprognostic (1.27e-2)" "potential prognostic favorable (7.20e-7)" "unprognostic (1.86e-1)" "unprognostic (1.76e-1)" "unprognostic (7.20e-2)" "unprognostic (7.41e-2)" "unprognostic (1.63e-1)" "unprognostic (9.65e-2)" "unprognostic (1.31e-1)" "unprognostic (4.58e-2)" "unprognostic (6.76e-2)" "unprognostic (1.52e-2)" "unprognostic (2.28e-3)" "unprognostic (6.34e-2)" "unprognostic (9.93e-3)" "unprognostic (2.08e-1)" "unprognostic (1.83e-1)" "unprognostic (1.26e-2)" "unprognostic (2.41e-2)" "unprognostic (3.01e-3)" "unprognostic (1.91e-1)" "unprognostic (1.14e-1)" FN3KRP "FLJ12171, FN3KL" ENSG00000141560 "Fructosamine 3 kinase related protein" Q9HA64 17 82716706-82730328 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 122.1;Migrating cytotrophoblasts: 95.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056172, HPA065831, HPA065939" Approved Approved Nucleoplasm NA NA 50000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 3 Nucleoplasm "HPA056172: , HPA065831: , HPA065939: " "unprognostic (1.77e-1)" "unprognostic (1.28e-1)" "unprognostic (2.45e-1)" "unprognostic (6.38e-2)" "unprognostic (3.73e-2)" "unprognostic (3.29e-2)" "potential prognostic unfavorable (6.24e-4)" "unprognostic (5.43e-1)" "unprognostic (3.02e-1)" "unprognostic (1.59e-2)" "potential prognostic favorable (1.10e-4)" "unprognostic (1.56e-3)" "unprognostic (3.04e-1)" "unprognostic (1.77e-2)" "unprognostic (1.00e-2)" "unprognostic (2.29e-2)" "unprognostic (2.25e-1)" "unprognostic (1.59e-1)" "unprognostic (4.40e-3)" "unprognostic (2.44e-1)" "unprognostic (4.58e-2)" "unprognostic (1.39e-2)" "unprognostic (2.13e-2)" "unprognostic (7.90e-3)" "unprognostic (2.62e-1)" "unprognostic (2.27e-1)" "unprognostic (5.35e-2)" "unprognostic (4.84e-2)" "unprognostic (7.63e-2)" "unprognostic (2.83e-1)" "unprognostic (3.64e-1)" FNBP1 "FBP17, KIAA0554" ENSG00000187239 "Formin binding protein 1" Q96RU3 9 129887187-130043189 "Disease related genes, Plasma proteins, Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 101.9" "Cell type enhanced" "Detected in many" "B-cells: 794.3;cDC: 934.8;Innate lymphoid cells: 811.8;Kupffer cells: 804.6;monocytes: 674.1;Neutrophils: 910.3;Oligodendrocytes: 669.4;Plasma cells: 701.5;T-cells: 883.6;Thymocytes: 672.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019635, HPA019691, HPA022119, HPA067742" Enhanced Supported "Vesicles,Plasma membrane" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 6: Non-specific - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 82: Dendritic cells - Antigen presentation" 26 "Plasma membrane" Vesicles "HPA019635: , HPA019691: , HPA022119: , HPA067742: " "unprognostic (1.56e-1)" "unprognostic (5.18e-2)" "unprognostic (1.65e-2)" "unprognostic (1.17e-3)" "unprognostic (3.52e-2)" "unprognostic (5.53e-2)" "unprognostic (1.92e-1)" "unprognostic (5.30e-2)" "unprognostic (3.23e-2)" "unprognostic (2.63e-2)" "unprognostic (4.44e-3)" "unprognostic (4.86e-2)" "unprognostic (5.72e-2)" "unprognostic (3.54e-2)" "unprognostic (1.36e-1)" "unprognostic (2.36e-2)" "unprognostic (1.19e-3)" "unprognostic (1.64e-2)" "unprognostic (6.71e-2)" "unprognostic (2.52e-2)" "unprognostic (1.97e-1)" "unprognostic (1.96e-1)" "unprognostic (1.81e-2)" "unprognostic (3.87e-1)" "unprognostic (1.80e-3)" "unprognostic (7.78e-2)" "unprognostic (1.86e-1)" "unprognostic (1.40e-2)" "unprognostic (1.97e-1)" "unprognostic (3.00e-2)" "unprognostic (1.84e-1)" FNBP1L "C1orf39, FLJ20275, TOCA1" ENSG00000137942 "Formin binding protein 1 like" Q5T0N5 1 93448118-93554661 "Predicted intracellular proteins" "Autophagy, Endocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Lacrimal acinar cells: 496.4;Podocytes: 553.1;Renal collecting duct intercalated cells: 534.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "basophil: 7.3" "Lineage enriched" "Detected in many" 5 "granulocytes: 7.3" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065273 Approved Supported Vesicles,Cytosol NA NA "Cluster 41: Basophils - Unknown function" "Cluster 33: Thyroid gland - Tissue development" "Cluster 54: Immune cells - T cell receptor" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 10 "Vesicles, Cytosol" "HPA065273: " "unprognostic (3.36e-3)" "unprognostic (4.66e-2)" "unprognostic (1.58e-2)" "unprognostic (9.53e-3)" "unprognostic (1.24e-3)" "unprognostic (1.67e-1)" "unprognostic (1.06e-1)" "unprognostic (4.69e-2)" "unprognostic (7.32e-2)" "unprognostic (5.36e-2)" "potential prognostic favorable (4.51e-9)" "unprognostic (3.58e-3)" "unprognostic (3.58e-1)" "potential prognostic unfavorable (2.29e-4)" "unprognostic (1.20e-1)" "unprognostic (1.63e-1)" "unprognostic (2.57e-1)" "unprognostic (2.84e-1)" "unprognostic (2.92e-1)" "unprognostic (6.96e-2)" "unprognostic (1.47e-1)" "unprognostic (5.13e-2)" "unprognostic (1.65e-1)" "unprognostic (8.46e-2)" "potential prognostic favorable (5.02e-6)" "unprognostic (2.76e-1)" "unprognostic (1.56e-1)" "unprognostic (1.96e-1)" "unprognostic (3.02e-2)" "unprognostic (1.19e-1)" "unprognostic (2.52e-2)" FNBP4 KIAA1014 ENSG00000109920 "Formin binding protein 4" Q8N3X1 11 47716494-47767443 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bergmann glia: 147.9;Choroid plexus epithelial cells: 145.0;Distal convoluted tubule cells: 140.9;Microglia: 156.5;Oligodendrocyte progenitor cells: 144.7;Oligodendrocytes: 146.7;Podocytes: 154.3;Renal collecting duct intercalated cells: 141.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039485, HPA040029" Supported Enhanced Nucleoplasm NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 102: Non-specific - Mixed function" 3 Nucleoplasm "HPA039485: , HPA040029: " "unprognostic (8.64e-2)" "unprognostic (1.89e-1)" "unprognostic (5.26e-2)" "unprognostic (3.35e-2)" "unprognostic (3.31e-2)" "unprognostic (1.26e-1)" "unprognostic (1.61e-1)" "unprognostic (3.23e-2)" "unprognostic (8.14e-3)" "unprognostic (1.12e-1)" "potential prognostic unfavorable (6.38e-4)" "unprognostic (1.40e-1)" "unprognostic (9.09e-2)" "potential prognostic unfavorable (3.91e-6)" "unprognostic (7.50e-2)" "unprognostic (1.34e-2)" "unprognostic (3.07e-2)" "unprognostic (1.22e-2)" "unprognostic (8.62e-2)" "unprognostic (9.51e-2)" "unprognostic (2.08e-1)" "unprognostic (2.82e-1)" "potential prognostic unfavorable (3.78e-4)" "unprognostic (1.21e-2)" "unprognostic (3.10e-3)" "potential prognostic favorable (2.71e-6)" "unprognostic (6.49e-3)" "unprognostic (2.99e-1)" "unprognostic (1.56e-1)" "unprognostic (1.22e-1)" "unprognostic (9.16e-2)" FNDC1 "bA243O10.1, dJ322A24.1, FNDC2, KIAA1866" ENSG00000164694 "Fibronectin type III domain containing 1" Q4ZHG4 6 159169400-159272108 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 13.3;intestine: 13.2;thyroid gland: 19.0" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 19.6;Ependymal cells: 92.0;Fibro-adipogenic progenitors: 67.8;Fibroblasts: 9.4;Retinal amacrine cells: 45.3" "Cell type enhanced" "Detected in some" "ependymal cell: 62.3;hippocampal CA1-3: 71.9" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 51.7" "Group enriched" "Detected in many" 6 "cerebral cortex: 11.9;hippocampal formation: 18.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 12.8;Kidney cancer: 9.5;Rhabdoid: 18.7" "Adrenal gland - Fibroblasts, Liver - Hepatic stellate cells, Minor Salivary Gland - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblasts_1, Stomach - Fibroblasts" "Region enhanced" "Detected in many" "olfactory bulb: 7.0" "Region enhanced" "Detected in many" "spinal cord: 12.5" "HPA030962, HPA030963" Approved Approved "Nuclear speckles" "Secreted to extracellular matrix" "No annotated function" NA NA 15000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 29: Forebrain - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 34: Ciliated cells - Cilia assembly & function" "Nuclear speckles" "HPA030962: , HPA030963: " "unprognostic (3.11e-3)" "unprognostic (1.51e-1)" "unprognostic (2.87e-1)" "unprognostic (2.49e-2)" "unprognostic (2.07e-2)" "unprognostic (3.10e-2)" "unprognostic (6.12e-2)" "unprognostic (1.09e-1)" "unprognostic (2.80e-1)" "potential prognostic unfavorable (2.57e-8)" "unprognostic (8.23e-2)" "unprognostic (5.34e-2)" "unprognostic (1.51e-2)" "unprognostic (2.79e-2)" "unprognostic (9.31e-2)" "unprognostic (1.88e-1)" "unprognostic (9.94e-2)" "potential prognostic unfavorable (3.12e-4)" "unprognostic (2.31e-2)" "unprognostic (3.77e-3)" "unprognostic (1.21e-1)" "unprognostic (3.44e-3)" "unprognostic (1.36e-1)" "unprognostic (2.54e-3)" "unprognostic (1.82e-1)" "unprognostic (2.89e-1)" "unprognostic (1.90e-1)" FNDC10 C1orf233 ENSG00000228594 "Fibronectin type III domain containing 10" F2Z333 1 1598012-1600135 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 24.3;brain: 27.8" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 14.1;Gonadotrophs: 19.0;Megakaryocytes: 12.4;Other brain neurons: 24.5;Parietal cells: 12.4;Respiratory ionocytes: 15.2;Retinal amacrine cells: 14.5;Undifferentiated spermatogonia: 18.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 1.6" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Pituitary gland - Gonadotropes, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 36: Brain & Liver - Signaling" "Cluster 1: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" "unprognostic (1.93e-1)" "unprognostic (1.36e-1)" "unprognostic (2.90e-1)" "unprognostic (8.68e-2)" "unprognostic (4.10e-3)" "unprognostic (7.03e-2)" "unprognostic (3.04e-2)" "unprognostic (6.82e-2)" "unprognostic (1.50e-1)" "potential prognostic unfavorable (4.96e-6)" "unprognostic (1.00e-2)" "potential prognostic favorable (3.51e-4)" "unprognostic (1.32e-2)" "unprognostic (5.28e-2)" "unprognostic (4.00e-1)" "unprognostic (3.38e-1)" "unprognostic (5.69e-2)" "unprognostic (2.62e-1)" "unprognostic (2.98e-1)" "unprognostic (1.23e-1)" "unprognostic (1.88e-1)" "unprognostic (1.18e-1)" "unprognostic (6.37e-2)" "unprognostic (8.49e-2)" "unprognostic (2.29e-1)" "unprognostic (3.23e-2)" "unprognostic (2.44e-1)" "unprognostic (1.98e-2)" "unprognostic (2.91e-2)" FNDC11 "C20orf195, MGC5356" ENSG00000125531 "Fibronectin type III domain containing 11" Q9BVV2 20 63547891-63556695 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 47 "testis: 106.2" "Group enriched" "Detected in some" 5 "Early spermatids: 1355.1;Late primary spermatocytes: 676.0" "Cell type enriched" "Detected in single" 4 "ependymal cell: 3.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 5 "memory B-cell: 1.5;naive B-cell: 3.3" "Lineage enriched" "Detected in single" 7 "B-cells: 3.3" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA041341 Approved Nucleoplasm,Vesicles,Aggresome NA NA "Cluster 34: B-cells - Unknown function" "Cluster 79: Testis - Spermatogenesis" "Cluster 46: Brainstem - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 54 "Nucleoplasm, Vesicles" Aggresome "HPA041341: " "unprognostic (1.30e-1)" "unprognostic (6.55e-2)" "unprognostic (7.81e-2)" "unprognostic (2.08e-2)" "unprognostic (1.19e-1)" "unprognostic (4.12e-2)" "unprognostic (1.01e-2)" "unprognostic (3.41e-1)" "unprognostic (4.36e-1)" "unprognostic (4.38e-2)" "unprognostic (3.11e-1)" "unprognostic (1.72e-1)" "unprognostic (1.57e-1)" "unprognostic (1.10e-1)" FNDC3A "bA203I16.5, FNDC3, KIAA0970" ENSG00000102531 "Fibronectin type III domain containing 3A" Q9Y2H6 13 48975912-49209779 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 961.0;Neutrophils: 1312.6;Plasma cells: 1164.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Endothelial cells, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008927, HPA012555, HPA012825" Approved Approved "Nucleoplasm,Golgi apparatus,Centrosome,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 22: Epididymis - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 19: Non-specific - Unknown function" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 10 "Nucleoplasm, Golgi apparatus, Centrosome" Cytosol "HPA008927: , HPA012555: , HPA012825: " "unprognostic (1.37e-1)" "unprognostic (1.12e-1)" "unprognostic (2.38e-1)" "potential prognostic unfavorable (3.50e-4)" "unprognostic (8.88e-2)" "unprognostic (4.47e-2)" "unprognostic (1.24e-1)" "unprognostic (1.58e-1)" "unprognostic (1.89e-1)" "unprognostic (5.36e-2)" "potential prognostic favorable (2.37e-6)" "unprognostic (3.27e-3)" "unprognostic (2.56e-2)" "unprognostic (4.84e-2)" "unprognostic (5.80e-2)" "unprognostic (1.11e-1)" "unprognostic (2.13e-2)" "unprognostic (1.84e-3)" "unprognostic (1.25e-1)" "unprognostic (7.68e-2)" "unprognostic (5.24e-3)" "unprognostic (1.35e-2)" "unprognostic (2.05e-1)" "unprognostic (1.44e-1)" "unprognostic (2.72e-1)" "unprognostic (2.47e-1)" "unprognostic (1.35e-1)" "unprognostic (8.98e-2)" "unprognostic (1.86e-1)" "unprognostic (1.78e-1)" "unprognostic (1.16e-1)" FNDC3B "DKFZp762K137, FAD104, FLJ23399, PRO4979, YVTM2421" ENSG00000075420 "Fibronectin type III domain containing 3B" Q53EP0 3 172039578-172401669 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial glandular cells: 1961.7;monocytes: 1986.6;Neutrophils: 6467.4;Plasma cells: 1963.7" "Cell type enhanced" "Detected in all" "fibroblast: 714.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 37.9" "Lineage enriched" "Detected in all" 4 "granulocytes: 37.9" "Low cancer specificity" "Detected in all" "Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007859 Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 12: Non-specific - Vasculature" "Cluster 63: Non-specific - Protein processing" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 6 "Endoplasmic reticulum" "HPA007859: " "unprognostic (2.10e-1)" "unprognostic (1.54e-1)" "unprognostic (1.08e-1)" "potential prognostic unfavorable (1.43e-6)" "unprognostic (1.65e-1)" "unprognostic (9.53e-2)" "unprognostic (2.83e-3)" "unprognostic (5.29e-3)" "unprognostic (2.88e-1)" "potential prognostic unfavorable (7.45e-5)" "unprognostic (4.77e-3)" "unprognostic (1.38e-1)" "unprognostic (3.00e-2)" "unprognostic (2.61e-3)" "unprognostic (3.73e-3)" "unprognostic (3.32e-3)" "unprognostic (1.33e-2)" "unprognostic (2.06e-1)" "unprognostic (6.22e-2)" "unprognostic (1.56e-1)" "potential prognostic unfavorable (8.61e-6)" "validated prognostic unfavorable (8.50e-4)" "validated prognostic unfavorable (1.22e-4)" "unprognostic (1.02e-1)" "unprognostic (3.77e-1)" "unprognostic (3.20e-1)" "unprognostic (6.48e-2)" "unprognostic (1.29e-2)" "unprognostic (2.30e-1)" "unprognostic (3.52e-2)" "unprognostic (1.10e-1)" FNDC4 "FLJ22362, FRCP1" ENSG00000115226 "Fibronectin type III domain containing 4" Q9H6D8 2 27491883-27495200 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 124.6;liver: 125.5" "Group enriched" "Detected in many" 4 "Early spermatids: 282.2;Esophageal apical cells: 416.9;Late spermatids: 1056.9" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 74.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 16.8" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051804, HPA063581" Uncertain Approved Nucleoplasm,Aggresome,Cytosol "Intracellular and membrane" "No annotated function" NA NA "Cluster 76: Non-specific - Metabolism" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 7: Liver cancer - Metabolism" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" Nucleoplasm "Aggresome, Cytosol" "HPA051804: , HPA063581: " "unprognostic (4.13e-1)" "unprognostic (1.14e-1)" "unprognostic (1.64e-1)" "unprognostic (7.31e-3)" "unprognostic (1.47e-2)" "unprognostic (8.46e-2)" "potential prognostic unfavorable (9.11e-4)" "unprognostic (6.01e-2)" "unprognostic (1.10e-1)" "unprognostic (2.86e-3)" "potential prognostic unfavorable (1.65e-4)" "unprognostic (5.02e-2)" "unprognostic (6.76e-2)" "potential prognostic unfavorable (8.37e-4)" "unprognostic (2.61e-1)" "unprognostic (3.16e-3)" "unprognostic (2.01e-2)" "unprognostic (9.33e-2)" "unprognostic (3.12e-2)" "unprognostic (7.30e-2)" "unprognostic (5.31e-2)" "unprognostic (4.34e-3)" "unprognostic (7.11e-2)" "unprognostic (1.04e-1)" "unprognostic (4.42e-2)" "unprognostic (2.55e-2)" "unprognostic (1.26e-1)" "unprognostic (9.05e-3)" "unprognostic (2.49e-3)" "unprognostic (3.22e-3)" "unprognostic (3.03e-3)" FNDC5 FRCP2 ENSG00000160097 "Fibronectin type III domain containing 5" Q8NAU1 1 32862268-32872482 "Predicted membrane proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "skeletal muscle: 302.5;tongue: 446.2" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 24.1;Adrenal medulla cells: 42.5;Brain inhibitory neurons: 33.5;Choroid plexus epithelial cells: 39.4;Early spermatids: 34.6;Fibro-adipogenic progenitors: 35.1;Müller glia: 31.4;Myonuclei: 36.8;Parietal cells: 24.8;Retinal amacrine cells: 45.4;Retinal bipolar cells: 41.3;Retinal pigment epithelial cells: 42.6;Salivary acinar cells: 27.7" "Cell type enhanced" "Detected in all" "cerebellar inhibitory: 86.4;midbrain-derived inhibitory: 120.5" "Group enriched" "Detected in many" 7 "Glioblastoma Multiforme (TCGA): 6.8;Kidney Chromophobe (TCGA): 4.9;Liver Hepatocellular Carcinoma (TCGA): 8.9;Testicular Germ Cell Tumor (TCGA): 17.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Neuroblastoma: 21.7;Sarcoma: 36.8" "Heart muscle - Cardiomyocytes, Prostate - Fibroblasts, Skeletal muscle - Skeletal myocytes, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051290 Enhanced "Intracellular and membrane" Hormone NA NA "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 109: Neurons - Neuronal signaling" 1 "HPA051290: " "unprognostic (9.81e-2)" "unprognostic (9.41e-2)" "unprognostic (4.11e-2)" "unprognostic (1.57e-3)" "unprognostic (3.85e-2)" "unprognostic (4.41e-2)" "potential prognostic favorable (1.71e-4)" "unprognostic (1.63e-2)" "unprognostic (2.70e-2)" "unprognostic (3.39e-1)" "unprognostic (1.10e-1)" "unprognostic (5.71e-2)" "unprognostic (2.07e-1)" "unprognostic (5.99e-3)" "unprognostic (7.41e-2)" "unprognostic (6.33e-3)" FNDC7 FLJ35838 ENSG00000143107 "Fibronectin type III domain containing 7" Q5VTL7 1 108712908-108742749 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "testis: 1.0" "Cell type enriched" "Detected in some" 4 "Ependymal cells: 38.9" "Cell type enhanced" "Detected in some" "Bergmann glia: 12.0;ependymal cell: 41.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA028079, HPA054297" Enhanced Approved "Nucleoplasm,Actin filaments" "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 67: Testis - Mixed function" "Cluster 46: Brainstem - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 34: Ciliated cells - Cilia assembly & function" "Actin filaments" Nucleoplasm "HPA028079: , HPA054297: " "unprognostic (4.22e-1)" FNDC8 DKFZp434H2215 ENSG00000073598 "Fibronectin type III domain containing 8" Q8TC99 17 35121615-35130732 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 500 "testis: 86.3" "Cell type enriched" "Detected in some" 4 "Late spermatids: 3565.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA026521, HPA059803" Supported Approved Cytosol NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 7 Cytosol "HPA026521: , HPA059803: " "unprognostic (6.47e-2)" FNDC9 "C5orf40, MGC27121" ENSG00000172568 "Fibronectin type III domain containing 9" Q8TBE3 5 157341598-157345677 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 27.1;pituitary gland: 11.2" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 3.2;Brain inhibitory neurons: 3.9;Loop of henle epithelial cells: 1.9;Other brain neurons: 13.0;Renal collecting duct principal cells: 1.3" "Cell type enhanced" "Detected in many" "eccentric medium spiny neuron: 8.8;splatter: 8.0" "Cancer enriched" "Detected in single" 15 "Glioblastoma Multiforme (TCGA): 1.4" "Region enhanced" "Detected in all" "hypothalamus: 83.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pituitary gland - Lactotropes" "Group enriched" "Detected in many" 5 "basal ganglia: 21.0;hypothalamus: 24.3" "Low region specificity" "Detected in all" NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 59: Leukemia - T-cell receptor" "Cluster 98: Neurons - Neurotransmission & signaling" 76 "unprognostic (1.48e-2)" "unprognostic (4.17e-1)" FNIP1 KIAA1961 ENSG00000217128 "Folliculin interacting protein 1" Q8TF40 5 131641714-131797017 "Disease related genes, Predicted intracellular proteins" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 9 "Astrocytes: 187.2;Bergmann glia: 220.0;Brain excitatory neurons: 173.5;Brain inhibitory neurons: 171.6;Choroid plexus epithelial cells: 296.6;Ependymal cells: 219.2;Microglia: 234.3;Oligodendrocyte progenitor cells: 171.2;Oligodendrocytes: 474.3;Other brain neurons: 139.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 16.5" "Lineage enriched" "Detected in all" 5 "granulocytes: 16.5" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA068099, HPA071213" Approved NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 22: Non-specific - Basic cellular functions" 12 "HPA068099: , HPA071213: " "unprognostic (6.84e-3)" "unprognostic (7.55e-3)" "unprognostic (2.48e-1)" "unprognostic (2.50e-2)" "unprognostic (6.54e-2)" "unprognostic (1.37e-1)" "unprognostic (1.82e-1)" "unprognostic (2.59e-2)" "unprognostic (7.31e-2)" "unprognostic (1.40e-3)" "potential prognostic favorable (6.93e-5)" "unprognostic (4.54e-3)" "unprognostic (2.38e-1)" "unprognostic (7.91e-2)" "unprognostic (1.04e-1)" "unprognostic (1.80e-1)" "unprognostic (1.31e-1)" "unprognostic (4.07e-2)" "unprognostic (8.34e-2)" "unprognostic (1.08e-2)" "potential prognostic unfavorable (5.36e-4)" "unprognostic (3.34e-1)" "unprognostic (4.70e-3)" "unprognostic (4.61e-3)" "unprognostic (7.96e-3)" "unprognostic (2.00e-2)" "unprognostic (1.70e-2)" "unprognostic (1.88e-1)" "unprognostic (2.94e-1)" "unprognostic (5.71e-3)" "unprognostic (4.10e-1)" FNIP2 "FNIPL, KIAA1450, MAPO1" ENSG00000052795 "Folliculin interacting protein 2" Q9P278 4 158769026-158908050 "Predicted intracellular proteins" "DNA damage" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "cDC: 452.5;Endometrial glandular cells: 424.9;Macrophages: 530.6;monocytes: 610.2;Renal collecting duct intercalated cells: 426.6" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 52.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "intermediate monocyte: 3.3;myeloid DC: 2.1;non-classical monocyte: 7.2" "Group enriched" "Detected in many" 7 "dendritic cells: 2.1;monocytes: 7.2" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042779, HPA052758, HPA072420" Approved Supported "Centriolar satellite,Cytosol" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 76: Non-specific - Metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 4 Cytosol "Centriolar satellite" "HPA042779: , HPA052758: , HPA072420: " "unprognostic (1.28e-1)" "unprognostic (1.70e-1)" "unprognostic (5.30e-2)" "unprognostic (3.55e-2)" "unprognostic (3.21e-2)" "unprognostic (1.91e-1)" "unprognostic (2.29e-1)" "unprognostic (2.03e-3)" "unprognostic (2.26e-1)" "unprognostic (2.40e-1)" "potential prognostic favorable (4.76e-9)" "unprognostic (1.15e-3)" "unprognostic (1.13e-1)" "unprognostic (1.91e-1)" "unprognostic (1.58e-1)" "unprognostic (9.43e-3)" "unprognostic (1.35e-2)" "unprognostic (2.95e-2)" "unprognostic (1.55e-1)" "unprognostic (2.76e-1)" "unprognostic (6.24e-3)" "unprognostic (3.02e-2)" "unprognostic (4.05e-1)" "unprognostic (3.79e-1)" "unprognostic (2.70e-1)" "unprognostic (5.04e-1)" "unprognostic (6.15e-2)" "unprognostic (2.64e-1)" "unprognostic (1.69e-1)" "unprognostic (5.05e-2)" "unprognostic (1.74e-1)" FNTA "FPTA, PGGT1A, PTAR2" ENSG00000168522 "Farnesyltransferase, CAAX box, alpha" P49354 8 43034194-43085788 "Enzymes, Essential proteins, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Prenyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal suprabasal cells: 179.1;Syncytiotrophoblasts: 251.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010149, HPA018830" Approved Approved Cytosol NA NA 89000 "Cluster 25: Non-specific - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." 13 Cytosol "CAB010149: , HPA018830: " "unprognostic (1.09e-1)" "unprognostic (5.68e-2)" "unprognostic (2.61e-1)" "unprognostic (3.71e-3)" "unprognostic (9.94e-2)" "unprognostic (2.89e-1)" "unprognostic (1.76e-1)" "unprognostic (7.93e-3)" "unprognostic (6.71e-3)" "potential prognostic unfavorable (1.07e-5)" "unprognostic (3.41e-3)" "unprognostic (1.92e-2)" "potential prognostic unfavorable (2.27e-5)" "unprognostic (4.52e-2)" "unprognostic (6.93e-2)" "unprognostic (7.90e-3)" "unprognostic (6.67e-2)" "unprognostic (4.48e-2)" "unprognostic (1.08e-1)" "unprognostic (1.65e-1)" "unprognostic (1.62e-2)" "unprognostic (1.05e-2)" "unprognostic (1.82e-1)" "unprognostic (4.42e-1)" "unprognostic (2.05e-2)" "unprognostic (3.64e-1)" "unprognostic (2.56e-1)" "unprognostic (6.75e-2)" "unprognostic (3.65e-1)" "unprognostic (6.14e-2)" "unprognostic (6.45e-3)" FNTB FPTB ENSG00000257365 "Farnesyltransferase, CAAX box, beta" P49356 14 64986895-65062652 "Enzymes, Essential proteins, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Prenyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "brain: 136.3" "Cell type enhanced" "Detected in many" "Astrocytes: 51.4;Bergmann glia: 51.5;Brain excitatory neurons: 43.9;Brain inhibitory neurons: 39.9;Choroid plexus epithelial cells: 48.7;Ependymal cells: 42.2;Esophageal apical cells: 49.7;Megakaryocytes: 43.3;Oligodendrocytes: 111.8;Platelets: 132.4" "Cell type enhanced" "Detected in all" "oligodendrocyte: 210.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Spleen - Fibroblasts_1, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062743 Uncertain Approved Centrosome NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 69: Skin cancer - ECM organization" "Cluster 80: Oligodendrocytes - Myelination" 32 Centrosome "HPA062743: " "unprognostic (1.06e-2)" "unprognostic (7.93e-2)" "unprognostic (1.47e-1)" "unprognostic (1.91e-1)" "unprognostic (2.93e-1)" "unprognostic (7.04e-3)" "unprognostic (1.07e-1)" "unprognostic (1.76e-1)" "unprognostic (4.42e-2)" "unprognostic (2.02e-1)" "potential prognostic favorable (3.25e-5)" "unprognostic (1.46e-2)" "unprognostic (7.13e-2)" "potential prognostic unfavorable (2.92e-5)" "unprognostic (7.40e-2)" "unprognostic (1.04e-2)" "unprognostic (2.35e-2)" "unprognostic (2.44e-3)" "unprognostic (1.43e-1)" "unprognostic (2.20e-1)" "unprognostic (9.05e-3)" "unprognostic (1.18e-1)" "unprognostic (2.41e-1)" "unprognostic (1.35e-2)" "unprognostic (1.49e-1)" "unprognostic (1.10e-1)" "unprognostic (8.00e-2)" "unprognostic (6.98e-2)" "unprognostic (4.80e-1)" "unprognostic (1.28e-1)" "unprognostic (9.97e-2)" FOCAD "FLJ20375, KIAA1797" ENSG00000188352 Focadhesin Q5VW36 9 20658309-20995955 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 34.9" "Cell type enhanced" "Detected in all" "Brain excitatory neurons: 495.2;Brain inhibitory neurons: 496.8;Choroid plexus epithelial cells: 1039.9;Gonadotrophs: 498.6;Lactotrophs: 467.5;Somatotrophs: 501.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044907, HPA055015" Approved Supported Cytosol NA NA "Cluster 1: T-cells - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 8 Cytosol "HPA044907: , HPA055015: " "unprognostic (3.92e-1)" "unprognostic (4.44e-2)" "unprognostic (1.99e-2)" "unprognostic (2.69e-2)" "unprognostic (4.69e-2)" "unprognostic (1.33e-1)" "potential prognostic favorable (9.87e-4)" "unprognostic (1.76e-1)" "unprognostic (5.80e-2)" "potential prognostic favorable (6.06e-5)" "unprognostic (1.33e-1)" "potential prognostic favorable (3.65e-4)" "potential prognostic unfavorable (5.28e-5)" "unprognostic (9.19e-2)" "unprognostic (1.28e-2)" "unprognostic (2.98e-1)" "unprognostic (1.74e-1)" "unprognostic (3.04e-2)" "unprognostic (9.44e-2)" "unprognostic (8.52e-2)" "unprognostic (2.16e-1)" "unprognostic (1.40e-1)" "unprognostic (4.52e-3)" "unprognostic (7.81e-2)" "unprognostic (6.84e-2)" "unprognostic (7.35e-2)" "unprognostic (1.45e-1)" "unprognostic (1.74e-1)" "unprognostic (2.26e-1)" FOLH1 "FOLH, GCP2, GCPII, NAALAD1, NAALAdase, PSM, PSMA" ENSG00000086205 "Folate hydrolase 1" Q04609 11 49145092-49208638 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carboxypeptidase, Dipeptidase, Hydrolase, Metalloprotease, Multifunctional enzyme, Protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 250.9;prostate: 71.4" "Group enriched" "Detected in many" 6 "Oligodendrocytes: 498.6;Prostatic glandular cells: 1456.5" "Cell type enriched" "Detected in many" 5 "oligodendrocyte: 694.1" "Cancer enriched" "Detected in all" 17 "Prostate Adenocarcinoma (TCGA): 277.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 25 "prostate cancer: 262.4;Rhabdoid: 177.2" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Fibroblasts_1, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Fibroblasts, Prostate - Prostate glandular cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001451, HPA010593" Enhanced "Intracellular and membrane" Enzyme NA NA 6100 "Cluster 77: Intestine - Digestion" "Cluster 11: White matter - Signal transduction" "Cluster 3: Rhabdoid - Membrane components" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" "CAB001451: , HPA010593: " "unprognostic (5.40e-3)" "unprognostic (4.91e-2)" "unprognostic (9.15e-2)" "unprognostic (1.46e-2)" "unprognostic (3.97e-1)" "unprognostic (1.61e-1)" "unprognostic (1.78e-1)" "unprognostic (9.93e-2)" "unprognostic (6.16e-2)" "unprognostic (1.20e-1)" "potential prognostic favorable (3.69e-6)" "unprognostic (1.86e-2)" "potential prognostic unfavorable (3.87e-5)" "unprognostic (1.76e-3)" "unprognostic (9.30e-2)" "unprognostic (4.71e-2)" "unprognostic (1.91e-1)" "unprognostic (1.69e-2)" "potential prognostic favorable (2.33e-4)" "unprognostic (5.53e-3)" "unprognostic (1.14e-2)" "unprognostic (4.44e-3)" "unprognostic (7.67e-2)" "unprognostic (2.68e-1)" "unprognostic (1.55e-2)" "unprognostic (2.51e-1)" "unprognostic (5.39e-2)" "unprognostic (5.60e-2)" "unprognostic (1.34e-1)" "unprognostic (9.35e-2)" "unprognostic (1.47e-1)" FOLR1 "FOLR, FRalpha" ENSG00000110195 "Folate receptor alpha" P15328 11 72189558-72196323 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" Transport Receptor "FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "choroid plexus: 2860.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 426.1;Alveolar cells type 2: 247.2;Breast lactating cells: 1703.5;Cytotrophoblasts: 460.0;Epididymal efferent duct ciliated cells: 222.4;Fallopian secretory cells: 402.1;Fallopian tube ciliated cells: 789.3;Migrating cytotrophoblasts: 547.4;Submucosal glandular cells: 302.6;Syncytiotrophoblasts: 325.2;Transitional alveolar cells: 449.6" "Group enriched" "Detected in many" 4 "choroid plexus epithelial cell: 156.2;ependymal cell: 44.1" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 633.3" "Region enriched" "Detected in all" 38 "choroid plexus: 993.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "ovarian cancer: 85.2" "Kidney - Proximal tubular cells, Lung - Alveolar cells type 1, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Skin - Eccrine sweat gland cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted to blood" Receptor NA NA 448000 25000 "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 4: Breast lactating luminal cells - Lactation" 4 "unprognostic (1.62e-2)" "unprognostic (3.07e-1)" "unprognostic (7.33e-2)" "unprognostic (3.44e-1)" "unprognostic (8.91e-2)" "unprognostic (1.32e-1)" "unprognostic (5.36e-3)" "unprognostic (1.16e-3)" "unprognostic (1.05e-2)" "unprognostic (2.85e-1)" "potential prognostic favorable (3.68e-4)" "unprognostic (2.11e-1)" "unprognostic (6.32e-2)" "potential prognostic unfavorable (3.17e-4)" "unprognostic (4.26e-2)" "unprognostic (4.55e-3)" "unprognostic (6.90e-2)" "unprognostic (5.50e-2)" "unprognostic (8.25e-2)" "unprognostic (5.34e-2)" "unprognostic (7.13e-2)" "unprognostic (4.34e-2)" "unprognostic (2.35e-1)" "unprognostic (9.84e-3)" "unprognostic (2.70e-1)" "unprognostic (3.06e-2)" "unprognostic (1.71e-1)" "unprognostic (1.71e-1)" "unprognostic (1.76e-1)" "unprognostic (4.19e-2)" FOLR2 FRbeta ENSG00000165457 "Folate receptor beta" P14207 11 72216601-72221950 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Transport Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 158.2" "Cell type enriched" "Detected in some" 4 "Hofbauer cells: 2520.8" "Cell type enriched" "Detected in some" 23 "central nervous system macrophage: 38.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 64.4;intermediate monocyte: 50.8" "Group enriched" "Detected in many" 4 "dendritic cells: 18.8;monocytes: 64.4" "Group enriched" "Detected in some" 18 "Leukemia: 1.8;lymphoma: 4.2" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Minor Salivary Gland - Macrophages, Skeletal muscle - Macrophages, Spleen - Macrophages, Testis - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" Receptor NA NA 4000000 3400000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 23: Choroid plexus - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" "unprognostic (2.38e-1)" "unprognostic (2.13e-1)" "unprognostic (1.29e-1)" "unprognostic (1.18e-1)" "unprognostic (5.02e-2)" "unprognostic (5.95e-2)" "unprognostic (1.89e-1)" "unprognostic (6.93e-2)" "unprognostic (2.17e-1)" "unprognostic (1.67e-1)" "unprognostic (2.24e-2)" "unprognostic (5.90e-2)" "unprognostic (2.59e-3)" "unprognostic (8.88e-2)" "unprognostic (4.35e-2)" "potential prognostic favorable (6.27e-4)" "unprognostic (3.82e-2)" "potential prognostic unfavorable (8.05e-4)" "unprognostic (3.23e-1)" "unprognostic (6.99e-2)" "unprognostic (3.87e-2)" "unprognostic (1.48e-1)" "unprognostic (3.24e-1)" "unprognostic (2.30e-1)" "unprognostic (2.51e-2)" "unprognostic (9.65e-2)" "unprognostic (9.34e-2)" "unprognostic (1.73e-3)" "unprognostic (3.38e-2)" "unprognostic (5.49e-3)" "unprognostic (3.12e-2)" FOLR3 "FR-G, FRgamma" ENSG00000110203 "Folate receptor gamma" P41439 11 72114869-72139892 "Metabolic proteins, Predicted secreted proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "bone marrow: 90.4;lymphoid tissue: 30.7" "Cell type enhanced" "Detected in some" "Late spermatids: 21.0;Monocyte progenitors: 46.1;monocytes: 43.7;Neutrophil progenitors: 75.2;Neutrophils: 185.8;Respiratory ionocytes: 15.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Head and Neck Squamous Cell Carcinoma (TCGA): 8.6;Kidney Chromophobe (TCGA): 13.1" "Not detected" "Not detected" "Group enriched" "Detected in many" 11 "classical monocyte: 325.3;neutrophil: 490.4" "Group enriched" "Detected in many" 11 "granulocytes: 490.4;monocytes: 325.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 11.2;Sarcoma: 5.6" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Spleen - Neutrophils_2" "Secreted to blood" Receptor NA NA 1200000 "Cluster 21: Neutrophils - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 1 "unprognostic (3.79e-1)" "unprognostic (2.99e-1)" "unprognostic (1.98e-1)" "unprognostic (3.86e-2)" "unprognostic (2.55e-1)" "unprognostic (9.95e-2)" "unprognostic (2.55e-3)" FOS "AP-1, c-fos" ENSG00000170345 "Fos proto-oncogene, AP-1 transcription factor subunit" P01100 14 75278826-75282230 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" DNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 6299.3;Endometrial luminal cells: 6202.5;Neutrophils: 6881.5;Ovarian stromal cells: 5794.0" "Group enriched" "Detected in all" 4 "astrocyte: 259.9;central nervous system macrophage: 281.5;endothelial cell: 364.6;ependymal cell: 315.8;vascular associated smooth muscle cell: 860.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 506.6" "Lineage enriched" "Detected in many" 6 "granulocytes: 506.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "cerebellum: 114.4;spinal cord: 324.5" "HPA018531, CAB080210" Approved Supported Nucleoplasm Yes No "Cluster 21: Neutrophils - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 55: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 122 Nucleoplasm "CAB080210: , HPA018531: " "unprognostic (2.84e-1)" "unprognostic (6.00e-2)" "unprognostic (1.05e-3)" "unprognostic (1.03e-2)" "unprognostic (3.97e-2)" "unprognostic (4.06e-2)" "unprognostic (1.71e-2)" "unprognostic (1.61e-1)" "unprognostic (4.99e-2)" "unprognostic (1.67e-1)" "unprognostic (3.67e-3)" "unprognostic (2.03e-3)" "unprognostic (1.67e-2)" "unprognostic (1.56e-1)" "unprognostic (2.96e-3)" "unprognostic (2.73e-2)" "unprognostic (1.37e-2)" "unprognostic (6.04e-2)" "unprognostic (1.69e-1)" "unprognostic (1.54e-3)" "unprognostic (2.17e-1)" "unprognostic (9.12e-2)" "unprognostic (1.12e-1)" "unprognostic (2.90e-3)" "unprognostic (2.01e-1)" "unprognostic (2.38e-3)" "unprognostic (1.17e-2)" "unprognostic (8.11e-3)" "unprognostic (3.80e-1)" "unprognostic (1.85e-1)" "unprognostic (1.24e-1)" FOSB "AP-1, DKFZp686C0818, G0S3, GOS3, GOSB, MGC42291" ENSG00000125740 "FosB proto-oncogene, AP-1 transcription factor subunit" P53539 19 45467995-45475179 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 1691.8;Breast secretory cells: 2187.2;Endometrial luminal cells: 1976.3;Mast cells: 1960.3;Salivary myoepithelial cells: 1716.6" "Cell type enriched" "Detected in many" 6 "vascular associated smooth muscle cell: 65.0" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 90.4" "Immune cell enhanced" "Detected in some" "neutrophil: 4.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB010267, HPA054663" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 15: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 20: Non-specific - Transcription regulation" 39 Nucleoplasm Vesicles "CAB010267: , HPA054663: " "unprognostic (3.06e-2)" "unprognostic (1.90e-1)" "potential prognostic favorable (6.37e-4)" "unprognostic (3.02e-1)" "unprognostic (5.08e-2)" "unprognostic (1.77e-1)" "unprognostic (1.19e-2)" "unprognostic (1.59e-1)" "unprognostic (3.21e-1)" "unprognostic (7.16e-2)" "validated prognostic favorable (3.68e-4)" "validated prognostic favorable (1.07e-7)" "unprognostic (2.35e-2)" "unprognostic (1.06e-2)" "unprognostic (1.90e-3)" "unprognostic (2.52e-3)" "unprognostic (1.20e-1)" "unprognostic (2.32e-2)" "unprognostic (1.63e-1)" "unprognostic (1.55e-2)" "unprognostic (1.24e-2)" "unprognostic (3.28e-1)" "unprognostic (4.40e-2)" "unprognostic (1.13e-1)" "unprognostic (2.30e-2)" "unprognostic (1.57e-2)" "unprognostic (5.16e-2)" "unprognostic (1.83e-3)" "unprognostic (1.14e-1)" "unprognostic (4.83e-2)" "unprognostic (1.55e-2)" FOSL1 fra-1 ENSG00000175592 "FOS like 1, AP-1 transcription factor subunit" P15407 11 65892049-65900573 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transcription factors" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 51.3;urinary bladder: 78.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 527.0;Epididymal basal cells: 446.6;Esophageal apical cells: 713.2;Esophageal basal cells: 394.6;Esophageal suprabasal cells: 567.5;Ocular epithelial cells: 468.4;Respiratory basal cells: 243.5;Suprabasal keratinocytes: 693.2;Urothelial cells: 461.7" "Group enriched" "Detected in some" 7 "central nervous system macrophage: 2.9;endothelial cell: 9.3" "Cancer enhanced" "Detected in all" "Head and Neck Squamous Cell Carcinoma (TCGA): 90.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "myeloid DC: 3.4" "Lineage enriched" "Detected in single" 4 "dendritic cells: 3.4" "Low cancer specificity" "Detected in all" "Colon - Neutrophils" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB004396, HPA030728" Enhanced Supported Nucleoplasm NA Yes "Cluster 10: Non-specific - Membrane trafficking" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 15: Non-specific - Transcription" "Cluster 72: Neuronal - Signal transduction" "Cluster 85: Squamous epithelial cells - Keratinization" 44 Nucleoplasm "CAB004396: , HPA030728: " "unprognostic (1.98e-3)" "unprognostic (2.77e-2)" "unprognostic (2.57e-1)" "unprognostic (5.46e-2)" "unprognostic (1.51e-1)" "unprognostic (2.60e-2)" "unprognostic (1.09e-3)" "unprognostic (4.60e-3)" "potential prognostic unfavorable (6.30e-4)" "unprognostic (6.43e-2)" "potential prognostic unfavorable (6.02e-6)" "unprognostic (4.95e-3)" "unprognostic (4.66e-1)" "unprognostic (3.82e-1)" "unprognostic (1.31e-2)" "potential prognostic unfavorable (1.21e-6)" "unprognostic (4.96e-3)" "unprognostic (3.71e-2)" "unprognostic (2.38e-3)" "unprognostic (1.77e-1)" "unprognostic (1.01e-1)" "validated prognostic unfavorable (2.56e-4)" "validated prognostic unfavorable (6.00e-4)" "unprognostic (5.01e-2)" "unprognostic (3.00e-1)" "unprognostic (1.78e-3)" "unprognostic (7.25e-2)" "unprognostic (2.48e-1)" "unprognostic (1.62e-1)" "unprognostic (5.97e-2)" "unprognostic (5.15e-2)" FOSL2 "FLJ23306, FRA2" ENSG00000075426 "FOS like 2, AP-1 transcription factor subunit" P15408 2 28392448-28417317 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 430.0;Esophageal apical cells: 455.4;monocytes: 475.3;Neutrophils: 697.0" "Group enriched" "Detected in many" 4 "endothelial cell: 126.2;leukocyte: 115.9;vascular associated smooth muscle cell: 224.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 36.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Neutrophils, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004817, CAB013460, HPA061417" Supported Enhanced Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 15: Bone marrow - Innate immune response" "Cluster 29: Forebrain - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 103: Non-specific - Basic cellular processes" 49 Nucleoplasm "CAB013460: , HPA004817: , HPA061417: " "unprognostic (9.31e-3)" "unprognostic (4.86e-2)" "unprognostic (2.91e-1)" "unprognostic (1.23e-2)" "unprognostic (4.93e-2)" "unprognostic (4.47e-2)" "unprognostic (4.60e-3)" "unprognostic (1.79e-1)" "unprognostic (5.00e-2)" "unprognostic (3.80e-1)" "unprognostic (4.94e-2)" "unprognostic (3.65e-2)" "unprognostic (1.45e-1)" "unprognostic (1.99e-1)" "unprognostic (1.04e-1)" "unprognostic (3.17e-3)" "unprognostic (1.03e-2)" "unprognostic (1.75e-1)" "unprognostic (7.04e-2)" "potential prognostic unfavorable (5.64e-4)" "unprognostic (1.00e-1)" "unprognostic (8.48e-3)" "unprognostic (1.54e-1)" "unprognostic (1.06e-1)" "unprognostic (8.91e-2)" "unprognostic (4.51e-3)" "unprognostic (2.98e-2)" "unprognostic (2.16e-1)" "unprognostic (2.23e-2)" "unprognostic (1.64e-2)" "unprognostic (1.28e-1)" FOXA1 HNF3A ENSG00000129514 "Forkhead box A1" P55317 14 37589552-37596059 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 70.2" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 195.9;Gastric chief cells: 134.3;Mucous neck cells: 146.1;Neuroendocrine cells: 89.7;Parietal cells: 159.1;Prostatic club cells: 164.0;Prostatic glandular cells: 293.2;Prostatic hillock cells: 102.3;Respiratory basal cells: 106.4;Respiratory ciliated cells: 120.2;Respiratory deuterosomal cells: 124.4;Respiratory secretory cells: 147.6;Urothelial cells: 147.0" "Cell type enriched" "Detected in single" 9 "ependymal cell: 6.8" "Group enriched" "Detected in many" 5 "Breast Invasive Carcinoma (TCGA): 139.7;Prostate Adenocarcinoma (TCGA): 201.2" "Region enriched" "Detected in some" 5 "midbrain: 7.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "breast cancer: 80.5;Gallbladder cancer: 38.9;prostate cancer: 122.3" "Breast - Breast glandular cells, Colon - Colon enterocytes, Liver - Hepatocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells" "Region enhanced" "Detected in some" "midbrain: 1.1" "Region enriched" "Detected in some" 6 "midbrain: 6.2" "CAB011595, HPA050505" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 60: Prostate cancer - Unknown function" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 36 Nucleoplasm "Nucleoli fibrillar center" "CAB011595: , HPA050505: " "potential prognostic favorable (1.41e-5)" "unprognostic (5.39e-2)" "unprognostic (1.56e-2)" "unprognostic (3.08e-1)" "unprognostic (1.34e-2)" "unprognostic (4.86e-1)" "unprognostic (1.46e-1)" "potential prognostic unfavorable (7.35e-7)" "unprognostic (1.57e-1)" "unprognostic (1.14e-2)" "unprognostic (1.95e-1)" "unprognostic (2.36e-2)" "unprognostic (1.21e-1)" "unprognostic (2.68e-1)" "unprognostic (2.85e-1)" "unprognostic (9.85e-2)" "unprognostic (4.51e-2)" "unprognostic (4.59e-2)" "unprognostic (6.02e-2)" "unprognostic (2.47e-1)" "unprognostic (1.65e-1)" "unprognostic (1.95e-1)" "unprognostic (1.38e-1)" "unprognostic (1.80e-1)" FOXA2 HNF3B ENSG00000125798 "Forkhead box A2" Q9Y261 20 22580998-22585455 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "liver: 34.8;pancreas: 25.2;stomach 1: 29.3" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 69.9;Alveolar cells type 2: 64.2;Cholangiocytes: 51.3;Endometrial glandular cells: 35.7;Fallopian tube ciliated cells: 76.5;Foveolar cells: 103.1;Gastric chief cells: 65.5;Goblet cells: 81.1;Hepatocytes: 76.7;Mucous neck cells: 55.7;Neuroendocrine cells: 40.7;Pancreatic acinar cells: 43.2;Pancreatic duct cells: 58.1;Pancreatic islet cells: 66.9;Paneth cells: 38.7;Parietal cells: 88.4;Transitional alveolar cells: 59.4" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 5 "midbrain: 5.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 20.2" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Region enriched" "Detected in single" 8 "midbrain: 5.2" "CAB001388, HPA066846" Enhanced Approved "Nucleoplasm,Cell Junctions" NA NA "Cluster 70: Non-specific - Protein processing" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 70: Intestinal goblet cells - Mucin production" 4 "Nucleoplasm, Cell Junctions" "CAB001388: , HPA066846: " "unprognostic (2.99e-3)" "unprognostic (1.37e-1)" "unprognostic (1.10e-1)" "unprognostic (6.91e-2)" "unprognostic (7.64e-2)" "unprognostic (3.88e-2)" "unprognostic (3.16e-2)" "unprognostic (1.74e-1)" "unprognostic (4.83e-2)" "unprognostic (3.49e-1)" "unprognostic (5.15e-3)" "unprognostic (1.54e-1)" "potential prognostic favorable (7.22e-4)" "unprognostic (3.79e-3)" "unprognostic (2.88e-1)" "unprognostic (3.90e-2)" "unprognostic (7.88e-2)" "unprognostic (1.55e-1)" "unprognostic (6.52e-2)" "unprognostic (1.04e-1)" FOXA3 HNF3G ENSG00000170608 "Forkhead box A3" P55318 19 45863989-45873797 "Predicted intracellular proteins, Transcription factors" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 16 "intestine: 16.4;liver: 60.4;pancreas: 45.5;stomach 1: 34.8" "Cell type enhanced" "Detected in some" "Colonocytes: 78.2;Enteric stem cells: 62.6;Enteric transient amplifying cells: 48.0;Foveolar cells: 92.2;Gastric chief cells: 50.2;Gastric progenitor cells: 37.2;Goblet cells: 310.7;Hepatocytes: 33.8;Mucous neck cells: 36.0;Neuroendocrine cells: 40.5;Pancreatic acinar cells: 110.2;Paneth cells: 73.5;Tuft cells: 46.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 12.6;colorectal cancer: 12.1;Gastric cancer: 15.9" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB015154, HPA054034" Uncertain Supported Nucleoplasm NA NA "Cluster 70: Non-specific - Protein processing" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 70: Intestinal goblet cells - Mucin production" 1 Nucleoplasm "CAB015154: , HPA054034: " "unprognostic (9.83e-2)" "unprognostic (5.85e-2)" "unprognostic (1.14e-1)" "unprognostic (8.70e-2)" "unprognostic (6.32e-2)" "unprognostic (8.35e-2)" "unprognostic (4.91e-2)" "unprognostic (1.30e-2)" "unprognostic (1.93e-1)" "unprognostic (2.39e-1)" "unprognostic (1.31e-1)" "unprognostic (1.51e-1)" "unprognostic (4.41e-1)" "unprognostic (4.09e-2)" "unprognostic (1.38e-2)" "unprognostic (1.85e-2)" "unprognostic (7.67e-2)" "unprognostic (3.45e-3)" "unprognostic (8.78e-2)" "unprognostic (2.75e-1)" "unprognostic (4.03e-1)" FOXB1 "FKH5, HFKH-5" ENSG00000171956 "Forkhead box B1" Q99853 15 60004234-60061730 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "brain: 3.9" "Cell type enhanced" "Detected in some" "Astrocytes: 10.4;Early spermatids: 18.0;Endometrial ciliated cells: 7.9;Endometrial glandular cells: 5.5;Ependymal cells: 5.8;Fallopian tube ciliated cells: 5.4;Late primary spermatocytes: 36.1;Late spermatids: 6.8" "Group enriched" "Detected in some" 11 "astrocyte: 26.7;ependymal cell: 18.0;mammillary body: 56.2" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 1.6" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "T-reg: 1.1" "Lineage enriched" "Detected in single" 12 "T-cells: 1.1" "Cancer enhanced" "Detected in some" "Leukemia: 3.3;prostate cancer: 3.1" "Testis - Early spermatids" "Region enhanced" "Detected in many" "hypothalamus: 6.6" "Low region specificity" "Detected in many" HPA073369 Approved Nucleoplasm,Mitochondria NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" 5 "Nucleoplasm, Mitochondria" "HPA073369: " "unprognostic (1.89e-1)" "unprognostic (2.01e-1)" FOXB2 bA159H20.4 ENSG00000204612 "Forkhead box B2" Q5VYV0 9 77019655-77020953 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in some" 4 "hypothalamus: 13.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 11 "hypothalamus: 1.1" "Group enriched" "Detected in many" 4 "basal ganglia: 4.4;hypothalamus: 8.7;medulla oblongata: 3.7;midbrain: 3.7;spinal cord: 6.8" HPA067947 Approved NA NA "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 109: Neurons - Neuronal signaling" "HPA067947: " FOXC1 "ARA, FKHL7, FREAC3, IGDA, IHG1, IRID1" ENSG00000054598 "Forkhead box C1" Q12948 6 1609915-1613897 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Angiogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Deafness, Disease variant, Peters anomaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "blood vessel: 80.4;salivary gland: 145.6" "Cell type enhanced" "Detected in many" "Lacrimal acinar cells: 388.6;Medullary thymic epithelial cells: 108.0;Ocular epithelial cells: 91.3;Podocytes: 201.8;Salivary acinar cells: 328.9;Salivary basal cells: 220.8;Salivary duct cells: 204.7;Salivary myoepithelial cells: 167.0;Submucosal glandular cells: 148.2;Vascular endothelial cells: 112.9;Vascular smooth muscle cells: 166.9" "Group enriched" "Detected in some" 212 "endothelial cell: 128.4;fibroblast: 109.9;pericyte: 74.8;vascular associated smooth muscle cell: 114.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Endothelial cells, Pituitary gland - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 23.7" HPA040670 Supported Nucleoplasm,Cytosol NA NA "Cluster 82: Salivary gland - Secretion" "Cluster 47: Endothelial cells - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 27 Nucleoplasm Cytosol "HPA040670: " "unprognostic (5.86e-2)" "unprognostic (5.29e-2)" "unprognostic (1.47e-1)" "unprognostic (6.29e-2)" "unprognostic (2.90e-3)" "unprognostic (7.83e-3)" "unprognostic (6.64e-2)" "potential prognostic unfavorable (2.00e-4)" "unprognostic (9.23e-2)" "unprognostic (1.01e-1)" "unprognostic (1.11e-2)" "unprognostic (2.32e-3)" "unprognostic (1.50e-2)" "unprognostic (5.16e-2)" "unprognostic (1.96e-2)" "unprognostic (7.63e-2)" "unprognostic (8.43e-2)" "unprognostic (5.67e-2)" "unprognostic (1.85e-2)" "unprognostic (9.86e-2)" "unprognostic (2.81e-2)" "potential prognostic unfavorable (3.68e-4)" "unprognostic (2.59e-2)" "unprognostic (1.68e-1)" "unprognostic (1.28e-1)" "unprognostic (4.43e-2)" "unprognostic (3.19e-3)" "unprognostic (1.21e-1)" "unprognostic (1.50e-1)" "unprognostic (6.35e-3)" "unprognostic (3.22e-3)" FOXC2 "FKHL14, MFH-1" ENSG00000176692 "Forkhead box C2" Q99958 16 86566829-86569728 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "blood vessel: 37.0" "Cell type enhanced" "Detected in some" "Hepatic stellate cells: 12.9;Lymphatic endothelial cells: 81.0;Ocular epithelial cells: 23.0;Pericytes: 24.0;Peritubular myoid cells: 36.1;Podocytes: 23.2;Salivary basal cells: 16.2;Submucosal glandular cells: 13.9;Undifferentiated spermatogonia: 13.9;Vascular smooth muscle cells: 69.4" "Group enriched" "Detected in some" 36 "fibroblast: 76.7;pericyte: 61.8;vascular associated smooth muscle cell: 82.8" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 7.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 16.3" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Adrenal gland - Fibroblasts, Lung - Smooth muscle cells" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 6 "spinal cord: 56.3" HPA056302 Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 103: Non-specific - Basic cellular processes" 7 "Nucleoplasm, Nuclear bodies" "HPA056302: " "unprognostic (2.49e-1)" "unprognostic (3.03e-2)" "unprognostic (1.45e-1)" "unprognostic (7.64e-3)" "unprognostic (2.11e-2)" "unprognostic (4.52e-2)" "unprognostic (2.25e-2)" "unprognostic (1.46e-2)" "unprognostic (2.04e-2)" "unprognostic (3.06e-2)" "unprognostic (7.70e-2)" "unprognostic (3.00e-1)" "unprognostic (6.25e-2)" "unprognostic (3.39e-3)" "unprognostic (3.42e-2)" FOXD1 "FKHL8, FREAC4" ENSG00000251493 "Forkhead box D1" Q16676 5 73444827-73448777 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Enterocytes: 6.7;Fibroblasts: 11.9;Late primary spermatocytes: 7.0;Müller glia: 23.6;Oocytes: 9.2;Pericytes: 12.7;Podocytes: 12.6;Respiratory basal cells: 6.1;Respiratory deuterosomal cells: 11.4;Respiratory ionocytes: 10.2;Retinal bipolar cells: 6.9;Retinal ganglion cells: 7.7;Retinal pigment epithelial cells: 21.3;Smooth muscle cells: 7.9;Thymic myoid cells: 6.8" "Group enriched" "Detected in some" 54 "fibroblast: 105.5;pericyte: 141.0;vascular associated smooth muscle cell: 50.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Fibroblasts, Kidney - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Region enhanced" "Detected in many" "spinal cord: 12.7" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 22: Non-specific - Basic cellular functions" 1 "unprognostic (1.85e-2)" "unprognostic (3.11e-3)" "unprognostic (2.00e-1)" "unprognostic (1.24e-3)" "unprognostic (6.88e-3)" "potential prognostic unfavorable (1.82e-5)" "unprognostic (3.37e-2)" "unprognostic (1.55e-3)" "unprognostic (1.99e-2)" "potential prognostic unfavorable (3.99e-4)" "unprognostic (1.89e-1)" "unprognostic (1.13e-3)" "unprognostic (1.26e-1)" "unprognostic (2.97e-3)" "unprognostic (3.42e-1)" "unprognostic (1.54e-1)" "unprognostic (4.22e-3)" "potential prognostic unfavorable (1.00e-4)" "unprognostic (7.49e-2)" "unprognostic (3.48e-2)" "unprognostic (6.84e-2)" "unprognostic (6.56e-2)" "unprognostic (2.68e-1)" FOXD2 "FKHL17, FREAC9" ENSG00000186564 "Forkhead box D2" O60548 1 47438044-47440691 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "blood vessel: 4.4;intestine: 5.8" "Cell type enhanced" "Detected in some" "Colonocytes: 24.1;Enteric stem cells: 16.6;Enteric transient amplifying cells: 14.5;Goblet cells: 13.0;Neuroendocrine cells: 7.6;Podocytes: 33.3;Respiratory deuterosomal cells: 9.3;Tuft cells: 46.1" "Group enriched" "Detected in some" 14 "fibroblast: 14.2;pericyte: 9.0;vascular associated smooth muscle cell: 8.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts" "Not detected" "Not detected" "Region enriched" "Detected in single" 7 "spinal cord: 5.4" NA NA "Cluster 77: Intestine - Digestion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 16 "unprognostic (1.37e-1)" "unprognostic (3.00e-3)" "unprognostic (9.18e-2)" "unprognostic (9.27e-3)" "unprognostic (4.79e-2)" "unprognostic (7.34e-2)" "unprognostic (9.68e-3)" "unprognostic (9.52e-2)" "unprognostic (4.62e-3)" "unprognostic (1.36e-1)" "unprognostic (7.28e-2)" "unprognostic (1.92e-1)" "unprognostic (1.80e-3)" "unprognostic (1.34e-1)" "unprognostic (1.61e-1)" "unprognostic (3.00e-1)" "unprognostic (9.56e-3)" FOXD3 "Genesis, HFH2" ENSG00000187140 "Forkhead box D3" Q9UJU5 1 63322567-63325128 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 4.9" "Cell type enhanced" "Detected in some" "Melanocytes: 15.1;Schwann cells: 69.9;Thymic myoid cells: 17.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Skin Cutaneous Melanoma (TCGA): 14.9;Testicular Germ Cell Tumor (TCGA): 4.6" "Region enriched" "Detected in some" 4 "medulla oblongata: 4.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Bone cancer: 3.2;skin cancer: 11.0" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Thyroid gland - Fibroblasts" "Region enriched" "Detected in single" 13 "olfactory bulb: 3.4" "Group enriched" "Detected in some" 13 "olfactory bulb: 11.5;spinal cord: 2.9" CAB022455 Uncertain NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 19: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 61: Schwann cells & Melanocytes - Mixed function" 4 "CAB022455: " "unprognostic (2.49e-1)" "potential prognostic favorable (1.72e-6)" "unprognostic (5.51e-2)" "unprognostic (2.36e-1)" "unprognostic (1.60e-1)" "unprognostic (8.69e-2)" "unprognostic (8.77e-2)" FOXD4 "FKHL9, FOXD4a, FREAC5" ENSG00000170122 "Forkhead box D4" Q12950 9 116231-118417 "Essential proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.7" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "upper rhombic lip: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "prostate cancer: 8.6" HPA012836 Uncertain Approved Nucleoplasm NA NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 37: Neurons - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 23 Nucleoplasm "HPA012836: " "unprognostic (1.50e-1)" "potential prognostic favorable (8.04e-5)" "unprognostic (3.84e-2)" FOXD4L1 FOXD5 ENSG00000184492 "Forkhead box D4 like 1" Q9NU39 2 113498665-113501150 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.0;testis: 1.1" "Cell type enhanced" "Detected in some" "Cholangiocytes: 2.0;Sertoli cells: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Leukemia: 2.0" "Testis - Early spermatids" "Not detected" "Not detected" "HPA012836, HPA069839" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 67: Testis - Mixed function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 19 Nucleoplasm Cytosol "HPA012836: , HPA069839: " "unprognostic (1.82e-1)" FOXD4L3 FOXD6 ENSG00000187559 "Forkhead box D4 like 3" Q6VB84 9 68302867-68305084 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA012836 Uncertain Approved Nucleoplasm NA NA "Cluster 51: Neurons - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 35: Neurons - Synaptic function & neurogenesis" 14 Nucleoplasm "HPA012836: " "unprognostic (7.36e-2)" FOXD4L4 "bA460E7.2, FOXD4L2" ENSG00000184659 "Forkhead box D4 like 4" Q8WXT5 9 65737146-65738396 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA012836 Uncertain Approved Nucleoplasm NA NA "Cluster 24: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 1 Nucleoplasm "HPA012836: " FOXD4L5 bA15J10.2 ENSG00000204779 "Forkhead box D4 like 5" Q5VV16 9 65282101-65285209 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 2.6" HPA012836 Uncertain Approved Nucleoplasm NA NA "Cluster 37: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" Nucleoplasm "HPA012836: " "unprognostic (2.86e-1)" FOXD4L6 ENSG00000273514 "Forkhead box D4 like 6" Q3SYB3 9 41126435-41128681 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "brain: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA012836 Uncertain Approved Nucleoplasm NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" 40 Nucleoplasm "HPA012836: " FOXE1 "FKHL15, FOXE2, HFKH4, TITF2, TTF-2" ENSG00000178919 "Forkhead box E1" O00358 9 97853226-97856717 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "thyroid gland: 182.0" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 9.6;Differentiating spermatogonia: 3.6;Early primary spermatocytes: 2.6;Epididymal basal cells: 6.8;Esophageal apical cells: 12.6;Esophageal basal cells: 6.1;Esophageal suprabasal cells: 8.1;Ocular epithelial cells: 6.0;Respiratory basal cells: 15.9;Respiratory secretory cells: 3.2;Suprabasal keratinocytes: 8.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Thyroid Carcinoma (TCGA): 122.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 38.9;cervical cancer: 20.8" "Skin - Inner root sheath cells, Skin - Outer root sheath cells, Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 33: Thyroid gland - Tissue development" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 1 "unprognostic (1.48e-1)" "unprognostic (4.47e-2)" "unprognostic (4.20e-2)" "unprognostic (3.35e-3)" "unprognostic (1.48e-3)" "potential prognostic favorable (1.49e-4)" "unprognostic (1.68e-1)" FOXE3 "FKHL12, FREAC8" ENSG00000186790 "Forkhead box E3" Q13461 1 47416285-47418052 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Aortic aneurysm, Cataract, Disease variant, Peters anomaly" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 1.4;Podocytes: 1.0;Undifferentiated spermatogonia: 3.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 1.2;Testicular Germ Cell Tumor (TCGA): 2.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 15 "Adrenocortical cancer: 2.5;testis cancer: 9.3" "Kidney - Podocytes" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 4: Non-specific - Transcription" "Cluster 106: Spermatogonia - Spermatogonial differentiation" "unprognostic (3.38e-2)" "unprognostic (1.27e-1)" FOXF1 "FKHL5, FREAC1" ENSG00000103241 "Forkhead box F1" Q12946 16 86510527-86515422 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 57.8;urinary bladder: 48.0" "Group enriched" "Detected in some" 9 "Fibroblasts: 44.7;Hepatic stellate cells: 38.7;Pericytes: 30.6;Smooth muscle cells: 32.5;Vascular endothelial cells: 26.0;Vascular smooth muscle cells: 28.9" "Cell type enriched" "Detected in some" 12 "endothelial cell: 55.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 13.6" "Breast - Endothelial cells, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA028886 Approved Nucleoplasm NA NA "Cluster 77: Intestine - Digestion" "Cluster 47: Endothelial cells - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 103: Non-specific - Basic cellular processes" 1 Nucleoplasm "HPA028886: " "unprognostic (6.48e-3)" "unprognostic (1.52e-1)" "unprognostic (1.70e-1)" "unprognostic (1.12e-1)" "unprognostic (1.42e-1)" "unprognostic (5.06e-2)" "unprognostic (5.60e-3)" "unprognostic (1.55e-2)" "unprognostic (1.56e-1)" "validated prognostic favorable (2.97e-4)" "validated prognostic favorable (1.39e-4)" "unprognostic (1.83e-3)" "unprognostic (8.65e-3)" "unprognostic (5.28e-2)" "unprognostic (2.75e-2)" "unprognostic (2.01e-1)" "unprognostic (2.51e-1)" "unprognostic (5.45e-2)" "unprognostic (3.78e-2)" "unprognostic (3.39e-1)" "unprognostic (1.86e-3)" "unprognostic (1.81e-2)" "unprognostic (8.46e-2)" "unprognostic (3.92e-2)" "unprognostic (7.79e-2)" FOXF2 "FKHL6, FREAC2" ENSG00000137273 "Forkhead box F2" Q12947 6 1389576-1395603 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 33.1" "Group enriched" "Detected in some" 4 "Fibroblasts: 18.0;Myosatellite cells: 13.9;Pericytes: 24.2;Vascular smooth muscle cells: 8.7" "Group enriched" "Detected in some" 9 "endothelial cell: 51.2;fibroblast: 52.6;pericyte: 82.6;vascular associated smooth muscle cell: 22.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Pituitary gland - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004763 Supported "Nucleoplasm,Nuclear bodies,Vesicles" NA NA "Cluster 77: Intestine - Digestion" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 72: Neuronal - Signal transduction" "Cluster 110: Mural cells - ECM organization" 8 "Nuclear bodies" "Nucleoplasm, Vesicles" "HPA004763: " "unprognostic (2.24e-2)" "unprognostic (1.63e-2)" "unprognostic (2.78e-1)" "unprognostic (8.66e-3)" "unprognostic (7.90e-2)" "unprognostic (2.07e-1)" "unprognostic (7.89e-2)" "unprognostic (1.48e-2)" "unprognostic (1.52e-2)" "unprognostic (8.87e-3)" "unprognostic (3.12e-1)" "unprognostic (1.65e-1)" "unprognostic (1.80e-1)" "unprognostic (8.02e-2)" "unprognostic (5.72e-2)" "unprognostic (2.24e-1)" "unprognostic (8.96e-2)" "unprognostic (5.01e-1)" "unprognostic (1.29e-2)" "unprognostic (9.01e-3)" "unprognostic (2.12e-1)" "unprognostic (1.28e-1)" "unprognostic (2.60e-2)" "unprognostic (1.10e-1)" FOXG1 "BF1, FKH2, FKHL1, FKHL2, FKHL3, FKHL4, FOXG1A, FOXG1B, FOXG1C, HBF-3, HFK1, HFK2, HFK3, QIN" ENSG00000176165 "Forkhead box G1" P55316 14 28764329-28770277 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 25.9" "Cell type enhanced" "Detected in some" "Astrocytes: 57.9;Brain excitatory neurons: 24.4;Brain inhibitory neurons: 39.4;Ependymal cells: 20.4;Medullary thymic epithelial cells: 9.6;Oligodendrocyte progenitor cells: 22.5;Other brain neurons: 11.1" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in some" 10 "Glioblastoma Multiforme (TCGA): 33.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 24.6" "Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 35: Neurons - Synaptic function & neurogenesis" 6 "unprognostic (2.34e-1)" "unprognostic (2.68e-2)" "unprognostic (2.89e-1)" FOXH1 FAST1 ENSG00000160973 "Forkhead box H1" O75593 8 144473412-144475849 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 13.6" "Cell type enhanced" "Detected in some" "Adipocytes: 6.9;Cardiomyocytes: 17.1;Colonocytes: 2.8;Epicardial cells: 34.1;Paneth cells: 3.9" "Low cell type specificity" "Detected in some" "Group enriched" "Detected in many" 4 "Testicular Germ Cell Tumor (TCGA): 73.4;Uterine Corpus Endometrial Carcinoma (TCGA): 20.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "testis cancer: 6.4" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 34: Testis cancer - Unknown function" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 55 "unprognostic (1.67e-2)" "unprognostic (3.40e-1)" "unprognostic (1.57e-1)" "potential prognostic favorable (5.34e-4)" "unprognostic (5.36e-3)" "unprognostic (1.31e-1)" "unprognostic (1.57e-1)" "unprognostic (1.08e-1)" "unprognostic (1.17e-2)" "unprognostic (7.02e-2)" "unprognostic (5.95e-2)" "unprognostic (8.74e-2)" "unprognostic (3.36e-1)" "unprognostic (9.29e-2)" "unprognostic (2.87e-1)" "unprognostic (2.91e-1)" "unprognostic (8.66e-2)" "unprognostic (1.14e-2)" "unprognostic (4.03e-3)" "unprognostic (1.39e-1)" "unprognostic (4.92e-2)" "unprognostic (2.15e-2)" FOXI1 "FKHL10, FREAC6" ENSG00000168269 "Forkhead box I1" Q12951 5 170105897-170109734 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 7.0;kidney: 36.0;salivary gland: 10.8" "Group enriched" "Detected in some" 10 "Epididymal clear cells: 353.1;Renal collecting duct intercalated cells: 129.0;Respiratory ionocytes: 190.5;Salivary ionocytes: 190.7" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 40 "Kidney Chromophobe (TCGA): 405.6" "Region enhanced" "Detected in single" "medulla oblongata: 1.2" "Immune cell enriched" "Detected in single" 16 "eosinophil: 1.5" "Lineage enriched" "Detected in single" 16 "granulocytes: 1.5" "Cancer enhanced" "Detected in some" "breast cancer: 4.2;testis cancer: 1.9" "Kidney - Intercalated cells, Minor Salivary Gland - Minor salivary gland ductal cells, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA071469 Enhanced Supported Nucleoli,Vesicles NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 43: Hindbrain - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 1 Nucleoli Vesicles "HPA071469: " "unprognostic (6.76e-1)" "unprognostic (2.22e-1)" "unprognostic (2.19e-1)" "unprognostic (1.91e-1)" "unprognostic (9.27e-2)" "unprognostic (1.19e-1)" "unprognostic (2.26e-1)" "unprognostic (1.43e-1)" "unprognostic (2.75e-2)" "unprognostic (6.66e-2)" FOXI2 FLJ46831 ENSG00000186766 "Forkhead box I2" Q6ZQN5 10 127737185-127741183 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "cervix: 1.6;esophagus: 1.8;kidney: 2.8" "Group enriched" "Detected in some" 4 "Epididymal clear cells: 20.4;Esophageal apical cells: 5.8;Respiratory ionocytes: 17.8;Salivary ionocytes: 22.1" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 26 "Kidney Chromophobe (TCGA): 58.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Intercalated cells, Minor Salivary Gland - Minor salivary gland ductal cells, Pituitary gland - Gonadotropes" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" "unprognostic (5.92e-2)" "unprognostic (2.83e-1)" "potential prognostic favorable (2.34e-8)" FOXI3 ENSG00000214336 "Forkhead box I3" A8MTJ6 2 88446787-88452693 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "placenta: 4.9;retina: 1.8" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 2.6;Cytotrophoblasts: 5.2;Migrating cytotrophoblasts: 3.1;Müller glia: 10.5;Syncytiotrophoblasts: 2.6" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Testicular Germ Cell Tumor (TCGA): 16.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 53 "testis cancer: 50.7" "Skin - Outer root sheath cells, Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 34: Testis cancer - Unknown function" "Cluster 11: Muller glia cells - Retinal homeostasis" "unprognostic (1.49e-1)" "unprognostic (1.76e-1)" "unprognostic (5.56e-2)" "unprognostic (2.00e-2)" "unprognostic (1.64e-1)" "unprognostic (4.83e-1)" "unprognostic (1.49e-1)" "unprognostic (5.27e-2)" FOXJ1 "FKHL13, HFH-4, HFH4" ENSG00000129654 "Forkhead box J1" Q92949 17 76136333-76141245 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Cilium biogenesis/degradation, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Ciliopathy, Disease variant, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 70.2;fallopian tube: 50.0" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 268.0;Ependymal cells: 145.6;Epididymal efferent duct ciliated cells: 287.9;Fallopian tube ciliated cells: 585.9;Respiratory ciliated cells: 276.1;Respiratory deuterosomal cells: 150.3" "Cell type enriched" "Detected in some" 4 "ependymal cell: 204.5" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 118.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 41.4" "Lung - Respiratory ciliated cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "midbrain: 53.4" HPA005714 Enhanced NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" 22 "HPA005714: " "unprognostic (2.36e-2)" "unprognostic (1.31e-3)" "unprognostic (1.18e-1)" "unprognostic (3.55e-2)" "unprognostic (2.41e-2)" "unprognostic (1.55e-1)" "unprognostic (7.59e-2)" "unprognostic (2.04e-2)" "unprognostic (2.24e-3)" "unprognostic (1.95e-1)" "validated prognostic unfavorable (3.59e-4)" "validated prognostic unfavorable (1.87e-4)" "unprognostic (5.47e-2)" "unprognostic (1.93e-1)" "unprognostic (2.15e-1)" "unprognostic (1.74e-1)" "unprognostic (5.18e-2)" "potential prognostic favorable (1.53e-4)" "unprognostic (1.88e-2)" "potential prognostic unfavorable (5.53e-4)" "unprognostic (2.39e-1)" "unprognostic (4.18e-1)" "unprognostic (6.85e-2)" "unprognostic (1.02e-1)" "unprognostic (1.96e-1)" "unprognostic (1.81e-1)" "unprognostic (1.75e-1)" FOXJ2 FHX ENSG00000065970 "Forkhead box J2" Q9P0K8 12 8032716-8055517 "Predicted intracellular proteins, Transcription factors" "Differentiation, Meiosis, Spermatogenesis, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008723 Approved Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 32: Basophils - Transcription" "Cluster 49: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 47: Platelets - Hemostasis" 3 Nucleoplasm "Nucleoli fibrillar center" "HPA008723: " "unprognostic (2.18e-2)" "unprognostic (9.26e-2)" "unprognostic (2.95e-2)" "unprognostic (2.22e-2)" "unprognostic (4.04e-2)" "unprognostic (2.43e-2)" "unprognostic (4.94e-2)" "unprognostic (1.93e-1)" "unprognostic (4.02e-1)" "unprognostic (9.40e-2)" "unprognostic (1.18e-3)" "potential prognostic favorable (8.35e-4)" "unprognostic (1.31e-1)" "unprognostic (1.74e-1)" "unprognostic (1.90e-1)" "unprognostic (9.03e-2)" "unprognostic (2.92e-1)" "unprognostic (1.28e-1)" "unprognostic (1.18e-1)" "unprognostic (6.69e-3)" "unprognostic (8.34e-2)" "unprognostic (1.42e-1)" "unprognostic (1.28e-2)" "unprognostic (2.91e-1)" "unprognostic (2.76e-1)" "unprognostic (2.29e-2)" "unprognostic (1.57e-1)" "unprognostic (9.79e-2)" "unprognostic (1.69e-1)" "unprognostic (3.40e-3)" "unprognostic (1.19e-1)" FOXJ3 KIAA1041 ENSG00000198815 "Forkhead box J3" Q9UPW0 1 42176539-42335877 "Predicted intracellular proteins, Transcription factors" "Differentiation, Meiosis, Spermatogenesis, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067284 Approved "Nucleoplasm,Nuclear speckles,Vesicles" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" "Nucleoplasm, Nuclear speckles" Vesicles "HPA067284: " "unprognostic (7.56e-2)" "unprognostic (1.37e-1)" "unprognostic (1.28e-1)" "unprognostic (2.17e-3)" "unprognostic (4.79e-2)" "unprognostic (3.94e-3)" "unprognostic (4.20e-2)" "unprognostic (2.73e-1)" "unprognostic (1.33e-1)" "unprognostic (1.46e-3)" "unprognostic (4.70e-2)" "unprognostic (2.71e-2)" "unprognostic (3.07e-1)" "potential prognostic unfavorable (1.39e-6)" "unprognostic (1.65e-2)" "unprognostic (1.12e-2)" "unprognostic (8.65e-2)" "unprognostic (1.18e-1)" "unprognostic (1.47e-1)" "unprognostic (4.08e-2)" "unprognostic (3.79e-1)" "unprognostic (1.36e-1)" "unprognostic (4.01e-2)" "unprognostic (5.87e-2)" "unprognostic (1.29e-1)" "unprognostic (3.47e-2)" "unprognostic (2.39e-1)" "unprognostic (2.43e-1)" "unprognostic (2.61e-1)" "unprognostic (1.83e-2)" "unprognostic (1.18e-1)" FOXK1 IMAGE:5164497 ENSG00000164916 "Forkhead box K1" P85037 7 4682295-4771442 "Predicted intracellular proteins, Transcription factors" "Differentiation, Host-virus interaction, Myogenesis, Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Lactotrophs: 296.5;Somatotrophs: 469.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017998, HPA018864" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 57 Nucleoplasm "Nucleoli fibrillar center" "HPA017998: , HPA018864: " "unprognostic (3.59e-2)" "unprognostic (1.76e-2)" "unprognostic (2.81e-2)" "potential prognostic unfavorable (8.67e-4)" "unprognostic (2.17e-1)" "unprognostic (9.82e-2)" "unprognostic (6.29e-2)" "unprognostic (3.91e-1)" "unprognostic (1.47e-1)" "unprognostic (3.81e-2)" "unprognostic (6.16e-3)" "unprognostic (6.35e-3)" "unprognostic (1.26e-1)" "validated prognostic unfavorable (6.98e-7)" "validated prognostic unfavorable (3.43e-4)" "unprognostic (1.75e-2)" "unprognostic (2.93e-2)" "unprognostic (2.83e-2)" "potential prognostic favorable (3.00e-4)" "unprognostic (4.25e-3)" "unprognostic (2.32e-1)" "unprognostic (5.49e-2)" "unprognostic (1.37e-1)" "unprognostic (9.08e-2)" "unprognostic (2.20e-1)" "unprognostic (1.26e-2)" "unprognostic (8.89e-2)" "unprognostic (3.57e-1)" "unprognostic (6.60e-2)" "unprognostic (1.10e-2)" "unprognostic (4.34e-1)" FOXK2 "ILF, ILF1" ENSG00000141568 "Forkhead box K2" Q01167 17 82519713-82644662 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027523, HPA073491" Approved Supported Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 103: Non-specific - Basic cellular processes" 45 Nucleoplasm "Vesicles, Mitochondria" "HPA027523: , HPA073491: " "unprognostic (1.97e-1)" "unprognostic (7.49e-2)" "unprognostic (2.74e-2)" "unprognostic (3.60e-1)" "unprognostic (3.84e-2)" "unprognostic (1.34e-1)" "unprognostic (7.77e-2)" "unprognostic (1.20e-2)" "unprognostic (1.49e-1)" "unprognostic (1.67e-2)" "unprognostic (9.49e-2)" "unprognostic (1.21e-1)" "unprognostic (6.02e-2)" "potential prognostic unfavorable (1.59e-7)" "unprognostic (7.31e-3)" "unprognostic (2.68e-2)" "potential prognostic unfavorable (7.13e-4)" "unprognostic (6.71e-2)" "unprognostic (1.51e-3)" "unprognostic (5.56e-2)" "unprognostic (8.80e-2)" "unprognostic (1.21e-2)" "unprognostic (4.78e-2)" "unprognostic (7.93e-2)" "unprognostic (4.34e-1)" "unprognostic (1.82e-1)" "unprognostic (3.75e-1)" "unprognostic (8.58e-2)" "unprognostic (1.62e-1)" "unprognostic (1.49e-1)" "unprognostic (1.81e-1)" FOXL1 "FKH6, FKHL11, FREAC7" ENSG00000176678 "Forkhead box L1" Q12952 16 86576368-86583478 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "blood vessel: 12.1" "Cell type enhanced" "Detected in some" "Fibroblasts: 4.5;Lacrimal acinar cells: 2.7;Lymphatic endothelial cells: 4.1;Pericytes: 6.1;Peritubular myoid cells: 10.7;Podocytes: 7.2;Salivary basal cells: 2.1;Salivary myoepithelial cells: 2.6;Submucosal glandular cells: 1.9;Vascular smooth muscle cells: 13.3" "Group enriched" "Detected in some" 54 "fibroblast: 13.9;pericyte: 25.9;vascular associated smooth muscle cell: 17.1" "Cancer enhanced" "Detected in many" "Pancreatic Adenocarcinoma (TCGA): 10.3" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "pancreatic cancer: 24.4" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Lung - Smooth muscle cells, Thyroid gland - Smooth muscle cells" "Not detected" "Not detected" "Region enriched" "Detected in single" 7 "spinal cord: 6.6" NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 110: Mural cells - ECM organization" 10 "unprognostic (5.14e-2)" "unprognostic (5.75e-2)" "unprognostic (9.64e-3)" "unprognostic (9.90e-2)" "unprognostic (1.49e-1)" "unprognostic (7.67e-2)" "unprognostic (1.11e-2)" "unprognostic (1.54e-1)" "unprognostic (9.08e-2)" "unprognostic (5.13e-2)" "unprognostic (3.32e-2)" "potential prognostic unfavorable (2.41e-4)" "unprognostic (1.37e-3)" "unprognostic (3.73e-1)" "unprognostic (2.66e-2)" "unprognostic (8.33e-2)" "unprognostic (2.85e-1)" "unprognostic (1.29e-1)" FOXL2 "BPES, BPES1" ENSG00000183770 "Forkhead box L2" P58012 3 138944224-138947137 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant, Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 13.7;fallopian tube: 13.0;ovary: 43.4" "Cell type enhanced" "Detected in some" "Decidual stromal cells: 17.2;Endometrial stromal cells: 31.6;Gonadotrophs: 75.2;Granulosa cells: 142.7;Ovarian stromal cells: 43.1;Smooth muscle cells: 14.3;Thyrotrophs: 15.4" "Cell type enriched" "Detected in single" 20 "endothelial cell: 18.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Pituitary gland - Thyrotropes" "Not detected" "Not detected" HPA069613 Enhanced Supported Nucleoplasm NA NA "Cluster 75: Ovary - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 94: Gonadal somatic cells - Mixed function" 2 Nucleoplasm "HPA069613: " "unprognostic (1.09e-3)" "unprognostic (4.40e-2)" "potential prognostic unfavorable (6.77e-4)" "unprognostic (1.39e-1)" "unprognostic (3.24e-2)" "unprognostic (8.39e-2)" "unprognostic (4.11e-1)" "unprognostic (1.84e-1)" FOXL2NB "C3orf72, FLJ43329" ENSG00000206262 "FOXL2 neighbor" Q6ZUU3 3 138947217-138953990 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "cervix: 21.4;ovary: 53.7;parathyroid gland: 30.7" "Cell type enhanced" "Detected in some" "Decidual stromal cells: 9.2;Endometrial stromal cells: 8.5;Gonadotrophs: 46.4;Granulosa cells: 24.3;Oocytes: 9.2;Ovarian stromal cells: 17.5;Smooth muscle cells: 7.3;Thyrotrophs: 11.8" "Cell type enriched" "Detected in single" 17 "endothelial cell: 15.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Pituitary gland - Thyrotropes, Testis - Early spermatids" "HPA061017, HPA071790" Enhanced "Nucleoli fibrillar center" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 94: Gonadal somatic cells - Mixed function" "Nucleoli fibrillar center" "HPA061017: , HPA071790: " "unprognostic (1.50e-1)" "unprognostic (1.50e-1)" "unprognostic (7.79e-3)" "unprognostic (4.52e-3)" "unprognostic (1.93e-1)" "unprognostic (1.89e-1)" FOXL3 ENSG00000248767 "Forkhead box L3" A0A1W2PRP0 7 290170-294422 "Predicted intracellular proteins" Transcription DNA-binding "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 27 "testis: 2.6" "Cell type enriched" "Detected in some" 6 "Late spermatids: 613.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 69: Skin cancer - ECM organization" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" FOXM1 "FKHL16, HFH-11, HNF-3, INS-1, MPHOSPH2, MPP2, TGT3, trident" ENSG00000111206 "Forkhead box M1" Q08050 12 2857680-2877174 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Cell cycle, DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 23.6;lymphoid tissue: 30.0;testis: 20.0" "Cell type enhanced" "Detected in many" "Enteric transient amplifying cells: 34.1;Epicardial cells: 31.8;Erythrocyte progenitors: 60.9;Esophageal basal cells: 25.8;Late primary spermatocytes: 25.5;Late spermatids: 33.9;Megakaryocyte progenitors: 48.5;Monocyte progenitors: 62.4;Neutrophil progenitors: 31.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" CAB017832 Uncertain Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" NA Yes "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 48: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 27: Non-specific - Cell proliferation" 39 "Nucleoplasm, Nucleoli, Nucleoli rim" Cytosol "CAB017832: " "unprognostic (8.62e-2)" "unprognostic (9.26e-2)" "unprognostic (5.09e-2)" "unprognostic (6.30e-2)" "unprognostic (7.89e-2)" "unprognostic (7.22e-2)" "unprognostic (6.25e-2)" "unprognostic (1.11e-1)" "unprognostic (1.83e-1)" "potential prognostic unfavorable (1.83e-4)" "validated prognostic unfavorable (7.50e-8)" "validated prognostic unfavorable (6.03e-6)" "potential prognostic unfavorable (3.66e-10)" "validated prognostic unfavorable (9.30e-5)" "validated prognostic unfavorable (7.32e-7)" "validated prognostic unfavorable (5.18e-5)" "validated prognostic unfavorable (8.54e-4)" "unprognostic (2.23e-2)" "unprognostic (4.76e-2)" "unprognostic (2.68e-1)" "unprognostic (2.75e-2)" "validated prognostic unfavorable (4.39e-4)" "validated prognostic unfavorable (1.94e-4)" "unprognostic (6.66e-3)" "unprognostic (3.87e-2)" "unprognostic (3.15e-2)" "unprognostic (2.41e-2)" "unprognostic (2.11e-2)" "unprognostic (1.94e-1)" "unprognostic (6.83e-2)" "unprognostic (2.00e-1)" FOXN1 "FKHL20, RONU, WHN" ENSG00000109101 "Forkhead box N1" O15353 17 28506243-28538900 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 17.4;skin 1: 38.8;vagina: 10.0" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 16.4;Early spermatids: 9.2;Esophageal basal cells: 24.2;Esophageal suprabasal cells: 28.8;Late spermatids: 22.7;Medullary thymic epithelial cells: 7.2;Prostatic hillock cells: 18.4;Respiratory basal cells: 7.1;Suprabasal keratinocytes: 36.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bladder Urothelial Carcinoma (TCGA): 3.3;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 12.8;Head and Neck Squamous Cell Carcinoma (TCGA): 12.6;Lung Squamous Cell Carcinoma (TCGA): 5.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "cervical cancer: 7.6;Esophageal cancer: 3.2;head and neck cancer: 2.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 58: Skin - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 8 "unprognostic (1.08e-1)" "unprognostic (2.39e-3)" "unprognostic (3.39e-3)" "potential prognostic favorable (2.25e-4)" "unprognostic (3.15e-2)" "unprognostic (2.41e-1)" "unprognostic (1.77e-1)" FOXN2 HTLF ENSG00000170802 "Forkhead box N2" P32314 2 48314637-48379295 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 50.8" "Cell type enhanced" "Detected in all" "cDC: 229.5;Monocyte progenitors: 299.8;Neutrophil progenitors: 403.8;Neutrophils: 471.7;Oligodendrocyte progenitor cells: 243.0;Oligodendrocytes: 359.5" "Cell type enhanced" "Detected in all" "oligodendrocyte: 436.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003485 Supported Supported Nucleoplasm,Vesicles NA NA "Cluster 41: Basophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 11: White matter - Signal transduction" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 82: Dendritic cells - Antigen presentation" 11 Nucleoplasm Vesicles "HPA003485: " "unprognostic (1.10e-1)" "unprognostic (3.43e-1)" "unprognostic (4.42e-1)" "unprognostic (9.63e-2)" "unprognostic (1.78e-1)" "unprognostic (1.23e-3)" "unprognostic (1.55e-2)" "unprognostic (9.94e-3)" "unprognostic (9.23e-2)" "unprognostic (1.99e-2)" "potential prognostic favorable (1.61e-6)" "unprognostic (5.11e-3)" "unprognostic (1.72e-2)" "unprognostic (1.71e-2)" "unprognostic (3.20e-3)" "unprognostic (1.06e-1)" "unprognostic (1.41e-3)" "unprognostic (2.87e-1)" "unprognostic (1.27e-1)" "unprognostic (8.21e-2)" "unprognostic (1.01e-1)" "unprognostic (5.82e-3)" "potential prognostic unfavorable (1.33e-4)" "unprognostic (7.25e-2)" "unprognostic (2.53e-3)" "unprognostic (4.20e-2)" "unprognostic (1.55e-1)" "unprognostic (1.08e-1)" "unprognostic (1.67e-1)" "unprognostic (2.92e-1)" "unprognostic (1.10e-2)" FOXN3 "C14orf116, CHES1" ENSG00000053254 "Forkhead box N3" O00409 14 89124871-89619149 "Predicted intracellular proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 995.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006180, HPA059209" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 54: Non-specific - Transcription" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 2 Nucleoplasm Cytosol "HPA006180: , HPA059209: " "unprognostic (1.49e-1)" "unprognostic (7.38e-2)" "unprognostic (9.85e-2)" "unprognostic (1.23e-1)" "unprognostic (1.89e-1)" "unprognostic (9.54e-3)" "unprognostic (4.66e-2)" "unprognostic (2.87e-1)" "unprognostic (2.34e-1)" "unprognostic (2.08e-2)" "potential prognostic favorable (1.65e-6)" "unprognostic (1.44e-3)" "unprognostic (8.77e-2)" "unprognostic (4.34e-1)" "unprognostic (1.62e-1)" "unprognostic (3.84e-2)" "unprognostic (2.75e-2)" "unprognostic (5.75e-2)" "unprognostic (2.78e-2)" "unprognostic (3.71e-2)" "potential prognostic unfavorable (6.11e-4)" "unprognostic (3.41e-1)" "unprognostic (5.57e-2)" "unprognostic (5.56e-2)" "unprognostic (1.32e-1)" "unprognostic (1.33e-1)" "unprognostic (1.25e-1)" "unprognostic (8.72e-3)" "unprognostic (2.66e-1)" "unprognostic (1.56e-1)" "unprognostic (1.04e-1)" FOXN4 ENSG00000139445 "Forkhead box N4" Q96NZ1 12 109277978-109309284 "Predicted intracellular proteins, Transcription factors" "Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "testis: 10.9" "Cell type enhanced" "Detected in some" "Adipocytes: 28.1;Differentiating spermatogonia: 10.7;Early spermatids: 5.1;Epicardial cells: 4.5;Late primary spermatocytes: 7.2;Late spermatids: 6.0;Podocytes: 5.2;Respiratory deuterosomal cells: 54.9;Undifferentiated spermatogonia: 4.5" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 2.2;ependymal cell: 2.2" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 3.4" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 3.5;prostate cancer: 3.4" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Lung - Respiratory ciliated cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA050018 Uncertain Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 89: Adipocytes - Lipid metabolism" 3 "Nucleoplasm, Mitochondria" Cytosol "HPA050018: " "unprognostic (1.21e-1)" "unprognostic (9.06e-3)" "unprognostic (1.76e-1)" "unprognostic (2.25e-1)" "unprognostic (3.83e-2)" "unprognostic (1.75e-1)" FOXO1 "FKH1, FKHR, FOXO1A" ENSG00000150907 "Forkhead box O1" Q12778 13 40555667-40666641 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Autophagy, Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 84.4" "Cell type enhanced" "Detected in many" "Adipocytes: 983.4;Decidual stromal cells: 606.2;Endometrial stromal cells: 609.2;Renal collecting duct intercalated cells: 873.1;Somatotrophs: 976.2;Thymic myoid cells: 921.8" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 402.2;endothelial cell: 551.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "lymphoma: 24.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001252, CAB022326, CAB080477, CAB080478, CAB080479" Supported Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 57 Nucleoplasm Cytosol "CAB022326: , CAB080477: , CAB080478: , CAB080479: , HPA001252: " "unprognostic (1.84e-2)" "unprognostic (7.58e-2)" "unprognostic (6.48e-2)" "unprognostic (6.64e-2)" "unprognostic (2.08e-1)" "unprognostic (1.46e-1)" "unprognostic (1.94e-1)" "potential prognostic unfavorable (7.65e-4)" "unprognostic (3.74e-1)" "unprognostic (1.19e-1)" "validated prognostic favorable (3.19e-6)" "validated prognostic favorable (8.60e-4)" "unprognostic (2.70e-1)" "unprognostic (4.34e-3)" "unprognostic (1.84e-1)" "unprognostic (6.79e-2)" "unprognostic (2.21e-1)" "unprognostic (3.46e-2)" "unprognostic (3.97e-2)" "validated prognostic unfavorable (5.38e-5)" "validated prognostic unfavorable (5.14e-4)" "unprognostic (1.79e-1)" "unprognostic (2.95e-3)" "unprognostic (1.61e-1)" "unprognostic (1.14e-1)" "unprognostic (3.04e-3)" "unprognostic (1.04e-1)" "unprognostic (1.44e-1)" "unprognostic (2.04e-1)" "unprognostic (3.17e-1)" "unprognostic (2.80e-2)" FOXO3 "AF6q21, FKHRL1, FOXO2, FOXO3A" ENSG00000118689 "Forkhead box O3" O43524 6 108559835-108684774 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 1186.3;Neutrophils: 3966.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 15.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004074, HPA063104" Supported Enhanced Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 2: Neurons - Nucleosome" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 64 Nucleoplasm "CAB004074: , HPA063104: " "unprognostic (1.21e-1)" "unprognostic (2.69e-3)" "unprognostic (2.02e-1)" "potential prognostic unfavorable (5.28e-4)" "unprognostic (1.90e-2)" "unprognostic (1.56e-1)" "unprognostic (4.35e-2)" "unprognostic (3.39e-1)" "unprognostic (1.14e-1)" "unprognostic (1.53e-1)" "potential prognostic favorable (2.79e-7)" "unprognostic (9.72e-3)" "unprognostic (1.24e-1)" "unprognostic (1.68e-3)" "unprognostic (5.03e-2)" "unprognostic (4.81e-2)" "unprognostic (2.57e-1)" "unprognostic (3.34e-1)" "unprognostic (1.25e-1)" "potential prognostic unfavorable (1.70e-4)" "unprognostic (8.26e-3)" "unprognostic (1.70e-2)" "unprognostic (8.16e-2)" "unprognostic (2.50e-1)" "unprognostic (2.51e-2)" "unprognostic (6.07e-3)" "unprognostic (3.04e-1)" "unprognostic (4.85e-2)" "unprognostic (2.28e-1)" "unprognostic (4.78e-2)" "unprognostic (2.90e-1)" FOXO3B FKHRL1P1 ENSG00000240445 "Forkhead box O3B" A0A2Z4LIS9 17 18667629-18682314 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 42: Non-specific - Unknown function" "Cluster 102: Non-specific - Mixed function" "unprognostic (2.96e-1)" "unprognostic (2.67e-1)" "unprognostic (1.94e-1)" "unprognostic (1.61e-1)" "unprognostic (1.87e-1)" "unprognostic (3.38e-1)" "unprognostic (2.56e-3)" "unprognostic (8.89e-2)" "unprognostic (1.23e-3)" "potential prognostic favorable (1.13e-4)" "unprognostic (5.75e-2)" "unprognostic (8.57e-2)" "unprognostic (3.22e-2)" "unprognostic (3.16e-2)" "unprognostic (1.14e-1)" "unprognostic (3.32e-1)" "unprognostic (1.78e-2)" "unprognostic (1.41e-1)" "unprognostic (1.99e-2)" "unprognostic (1.07e-1)" "unprognostic (4.71e-2)" "unprognostic (1.05e-1)" "unprognostic (1.56e-1)" FOXO4 "AFX1, MLLT7" ENSG00000184481 "Forkhead box O4" P98177 X 71095851-71103532 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, RAS pathway related proteins, Transcription factors" "Cell cycle, Differentiation, Myogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 109.6" "Group enriched" "Detected in many" 13 "Cytotrophoblasts: 317.0;Migrating cytotrophoblasts: 201.6;Syncytiotrophoblasts: 314.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "testis cancer: 22.8" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039560, HPA040232" Enhanced Supported "Nuclear speckles,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 14 "Nuclear speckles" Cytosol "HPA039560: , HPA040232: " "unprognostic (5.20e-3)" "unprognostic (1.12e-1)" "unprognostic (1.26e-1)" "unprognostic (8.14e-2)" "unprognostic (1.06e-1)" "unprognostic (2.31e-1)" "unprognostic (1.22e-1)" "potential prognostic favorable (2.73e-4)" "unprognostic (1.12e-2)" "unprognostic (1.80e-1)" "validated prognostic favorable (4.78e-7)" "validated prognostic favorable (2.70e-5)" "unprognostic (4.06e-2)" "unprognostic (1.03e-1)" "unprognostic (2.19e-1)" "unprognostic (2.71e-2)" "unprognostic (4.30e-2)" "unprognostic (2.86e-1)" "unprognostic (1.08e-1)" "unprognostic (9.86e-3)" "unprognostic (4.33e-2)" "unprognostic (1.66e-1)" "unprognostic (1.22e-1)" "unprognostic (8.43e-2)" "unprognostic (8.40e-2)" "unprognostic (1.58e-2)" "unprognostic (3.27e-1)" "unprognostic (6.11e-2)" "unprognostic (1.25e-1)" "unprognostic (1.07e-1)" "unprognostic (1.60e-2)" FOXO6 ENSG00000204060 "Forkhead box O6" A8MYZ6 1 41361922-41383590 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Astrocytes: 2.0;Brain excitatory neurons: 2.3;Brain inhibitory neurons: 2.6;Choroid plexus epithelial cells: 3.7;Ependymal cells: 5.9;Epicardial cells: 4.5;Loop of henle epithelial cells: 2.3;Oligodendrocyte progenitor cells: 3.0;Oligodendrocytes: 3.2;Other brain neurons: 5.8;Papillary tip epithelial cells: 3.5;Podocytes: 2.6;Renal collecting duct principal cells: 2.8;Thyrotrophs: 2.8" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 1.4;Sarcoma: 1.5" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 17: Choroid plexus - Cilium" "Cluster 11: Neuronal - Sensory perception" "Cluster 109: Neurons - Neuronal signaling" "unprognostic (1.61e-2)" "unprognostic (2.16e-1)" FOXP1 "12CC4, hFKH1B, HSPC215, QRF1" ENSG00000114861 "Forkhead box P1" Q9H334 3 70954693-71583978 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 744.6;Papillary tip epithelial cells: 624.8;Podocytes: 530.1;Renal collecting duct intercalated cells: 1997.8;Renal connecting tubule cells: 718.5" "Cell type enhanced" "Detected in all" "endothelial cell: 1494.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Skin - Endothelial cells" "Region enhanced" "Detected in all" "basal ganglia: 102.6" "Low region specificity" "Detected in all" "HPA003876, CAB011501" Supported Supported Nucleoplasm NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 53: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 32 Nucleoplasm "CAB011501: , HPA003876: " "unprognostic (3.30e-3)" "unprognostic (1.29e-1)" "unprognostic (1.17e-1)" "unprognostic (9.14e-3)" "unprognostic (1.50e-1)" "unprognostic (4.49e-2)" "unprognostic (1.89e-1)" "unprognostic (2.00e-2)" "unprognostic (6.27e-3)" "unprognostic (7.07e-3)" "unprognostic (8.34e-3)" "unprognostic (1.96e-3)" "unprognostic (2.43e-1)" "unprognostic (1.99e-1)" "unprognostic (4.88e-2)" "unprognostic (7.99e-2)" "unprognostic (5.45e-2)" "unprognostic (1.57e-2)" "unprognostic (1.12e-1)" "unprognostic (5.67e-2)" "unprognostic (1.12e-1)" "unprognostic (3.43e-3)" "unprognostic (1.01e-1)" "unprognostic (2.58e-1)" "unprognostic (2.55e-1)" "unprognostic (1.63e-1)" "unprognostic (2.51e-2)" "unprognostic (2.96e-1)" "unprognostic (7.60e-2)" "unprognostic (4.13e-2)" "unprognostic (2.64e-1)" FOXP2 "CAGH44, SPCH1, TNRC10" ENSG00000128573 "Forkhead box P2" O15409 7 114086327-114693772 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 17.4" "Cell type enhanced" "Detected in many" "Loop of henle epithelial cells: 691.4;Microglia: 864.9;Müller glia: 619.6;Myonuclei: 1201.1;Myosatellite cells: 538.8;Respiratory basal cells: 696.9;Respiratory ciliated cells: 747.7;Salivary acinar cells: 506.8" "Cell type enhanced" "Detected in all" "eccentric medium spiny neuron: 2928.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000382, HPA000383, HPA001679" Enhanced Enhanced Nucleoplasm NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 108: Fibroblasts - ECM organization" 31 Nucleoplasm "HPA000382: , HPA000383: , HPA001679: " "unprognostic (1.35e-1)" "unprognostic (2.43e-1)" "unprognostic (4.88e-2)" "unprognostic (1.07e-1)" "unprognostic (2.03e-1)" "unprognostic (1.30e-1)" "unprognostic (1.40e-1)" "unprognostic (1.23e-1)" "unprognostic (1.01e-1)" "unprognostic (8.60e-3)" "unprognostic (1.66e-1)" "unprognostic (2.75e-1)" "unprognostic (1.14e-1)" "unprognostic (1.06e-3)" "unprognostic (1.60e-1)" "unprognostic (1.05e-1)" "unprognostic (2.79e-2)" "unprognostic (1.64e-2)" "unprognostic (1.97e-1)" "unprognostic (9.14e-2)" "unprognostic (3.99e-2)" "unprognostic (1.80e-1)" "unprognostic (4.95e-3)" "unprognostic (3.60e-1)" "unprognostic (1.94e-1)" "unprognostic (1.17e-1)" "unprognostic (1.34e-3)" "unprognostic (1.16e-1)" "unprognostic (4.50e-3)" "unprognostic (8.07e-2)" FOXP3 "AIID, DIETER, IPEX, JM2, PIDX, SCURFIN, XPID" ENSG00000049768 "Forkhead box P3" Q9BZS1 X 49250438-49264800 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 4.9;lymphoid tissue: 6.6" "Cell type enhanced" "Detected in some" "Early primary spermatocytes: 1.6;Epididymal principal cells: 4.0;T-cells: 9.2;Thymic myoid cells: 1.4;Undifferentiated spermatogonia: 1.7" "Cell type enhanced" "Detected in single" "leukocyte: 1.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 11 "T-reg: 52.0" "Lineage enriched" "Detected in single" 360 "T-cells: 52.0" "Cancer enhanced" "Detected in some" "lymphoma: 3.7" "Thyroid gland - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB026301, HPA045943, HPA069372" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 15: Non-specific - Transcription" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" 34 Nucleoplasm Cytosol "CAB026301: , HPA045943: , HPA069372: " "potential prognostic favorable (3.53e-4)" "unprognostic (8.91e-2)" "unprognostic (7.65e-2)" "potential prognostic favorable (3.29e-4)" "unprognostic (2.03e-1)" "unprognostic (1.27e-1)" "potential prognostic favorable (2.20e-4)" "unprognostic (5.16e-2)" "potential prognostic unfavorable (1.98e-6)" "unprognostic (1.23e-1)" "potential prognostic unfavorable (9.07e-4)" "unprognostic (8.74e-2)" "unprognostic (5.00e-2)" "unprognostic (1.43e-1)" "unprognostic (3.17e-3)" "unprognostic (2.22e-1)" "unprognostic (1.66e-1)" "unprognostic (3.41e-2)" "unprognostic (3.31e-3)" "unprognostic (4.36e-3)" "unprognostic (1.59e-1)" "unprognostic (6.66e-2)" "unprognostic (3.40e-3)" "unprognostic (2.96e-2)" "unprognostic (1.99e-2)" "unprognostic (6.26e-2)" "unprognostic (3.03e-1)" "unprognostic (1.68e-1)" FOXP4 FLJ40908 ENSG00000137166 "Forkhead box P4" Q8IVH2 6 41546381-41602384 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Foveolar cells: 48.2;Goblet cells: 52.5;Mucous neck cells: 48.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006538, HPA007176, HPA076256" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 60: Stomach - Digestion" "Cluster 49: Hindbrain - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 23 Nucleoplasm Cytosol "HPA006538: , HPA007176: , HPA076256: " "unprognostic (9.39e-2)" "unprognostic (4.26e-2)" "unprognostic (1.76e-1)" "unprognostic (5.26e-2)" "unprognostic (1.59e-1)" "unprognostic (6.67e-2)" "unprognostic (2.53e-1)" "unprognostic (3.55e-1)" "unprognostic (1.91e-2)" "unprognostic (2.54e-1)" "unprognostic (9.63e-2)" "unprognostic (1.19e-1)" "unprognostic (3.14e-1)" "potential prognostic unfavorable (6.81e-4)" "unprognostic (3.54e-2)" "unprognostic (7.86e-2)" "unprognostic (1.26e-1)" "unprognostic (1.68e-1)" "unprognostic (7.52e-2)" "unprognostic (2.58e-1)" "unprognostic (2.21e-1)" "unprognostic (2.71e-3)" "unprognostic (2.04e-2)" "unprognostic (1.15e-1)" "unprognostic (7.50e-3)" "unprognostic (2.31e-1)" "unprognostic (1.17e-1)" "unprognostic (5.04e-2)" "unprognostic (2.74e-1)" "unprognostic (2.12e-2)" "unprognostic (9.64e-2)" FOXQ1 HFH1 ENSG00000164379 "Forkhead box Q1" Q9C009 6 1312098-1314758 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 101.2;urinary bladder: 50.0" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 82.1;Foveolar cells: 456.5;Gastric progenitor cells: 133.3;Mucous neck cells: 203.6;Ocular epithelial cells: 151.9;Prostatic club cells: 193.1;Prostatic hillock cells: 165.0;Salivary basal cells: 129.0;Salivary duct cells: 144.5;Urothelial cells: 273.8" "Cell type enhanced" "Detected in some" "endothelial cell: 122.7;fibroblast: 37.2;pericyte: 64.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 53.8" "Prostate - Urothelial cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA059700, CAB080325, CAB080326" Approved "Nucleoplasm,Nucleoli fibrillar center,Nuclear bodies" Yes NA "Cluster 60: Stomach - Digestion" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 68: Foveolar cells - Mucosal defense" 1 Nucleoplasm "Nucleoli fibrillar center, Nuclear bodies" "CAB080325: , CAB080326: , HPA059700: " "potential prognostic favorable (1.11e-4)" "potential prognostic favorable (3.84e-4)" "unprognostic (2.13e-2)" "unprognostic (2.42e-1)" "unprognostic (7.28e-2)" "unprognostic (7.10e-3)" "unprognostic (3.95e-3)" "unprognostic (2.76e-1)" "unprognostic (3.25e-1)" "unprognostic (3.11e-1)" "unprognostic (4.50e-2)" "unprognostic (4.08e-3)" "unprognostic (1.07e-3)" "unprognostic (1.14e-2)" "unprognostic (1.67e-2)" "unprognostic (2.16e-2)" "unprognostic (4.31e-2)" "unprognostic (7.18e-2)" "unprognostic (2.70e-1)" "unprognostic (6.57e-2)" "unprognostic (3.28e-1)" "unprognostic (3.85e-3)" "unprognostic (2.68e-2)" "unprognostic (1.12e-2)" "unprognostic (1.54e-1)" "unprognostic (1.02e-2)" "unprognostic (4.53e-2)" "unprognostic (3.11e-2)" "unprognostic (1.99e-1)" "unprognostic (1.76e-1)" "unprognostic (4.87e-2)" FOXR1 "DLNB13, FOXN5" ENSG00000176302 "Forkhead box R1" Q6PIV2 11 118971712-118981287 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 4 "testis: 4.1" "Cell type enriched" "Detected in some" 21 "Oocytes: 529.6" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 24 "Testicular Germ Cell Tumor (TCGA): 3.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 16 "Bone cancer: 14.8" "Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" HPA038124 Approved Nucleoplasm,Cytosol NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 42: Non-specific - Unknown function" "Cluster 41: Oocytes - Oogenesis" 28 Nucleoplasm Cytosol "HPA038124: " "unprognostic (1.67e-1)" FOXR2 "FOXN6, MGC21658" ENSG00000189299 "Forkhead box R2" Q6PJQ5 X 55623400-55626192 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 11 "testis: 1.2" "Group enriched" "Detected in some" 5 "Differentiating spermatogonia: 5.7;Sertoli cells: 5.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 3.7" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA034487, HPA057358" Uncertain Supported Nucleoplasm NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 9 Nucleoplasm "HPA034487: , HPA057358: " FOXRED1 H17 ENSG00000110074 "FAD dependent oxidoreductase domain containing 1" Q96CU9 11 126269024-126278131 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" Oxidoreductase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039620, HPA046192" Uncertain Supported Mitochondria NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 76: Non-specific - Metabolism" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 24: Non-specific - Unknown function" "Cluster 65: Non-specific - Cell growth & division" 4 Mitochondria "HPA039620: , HPA046192: " "unprognostic (1.92e-2)" "unprognostic (4.20e-3)" "unprognostic (3.54e-1)" "unprognostic (6.31e-2)" "unprognostic (3.41e-1)" "unprognostic (7.75e-2)" "unprognostic (6.45e-2)" "unprognostic (2.79e-2)" "unprognostic (1.03e-1)" "unprognostic (2.39e-1)" "potential prognostic favorable (6.61e-6)" "unprognostic (1.06e-1)" "potential prognostic favorable (2.11e-5)" "unprognostic (1.54e-1)" "unprognostic (2.03e-1)" "unprognostic (9.52e-3)" "unprognostic (3.86e-2)" "unprognostic (6.63e-2)" "unprognostic (4.07e-1)" "unprognostic (1.91e-1)" "unprognostic (9.51e-2)" "unprognostic (1.01e-1)" "unprognostic (1.78e-1)" "unprognostic (6.40e-2)" "unprognostic (4.96e-2)" "unprognostic (7.96e-2)" "unprognostic (2.77e-1)" "unprognostic (8.18e-2)" "unprognostic (3.39e-1)" "unprognostic (1.79e-1)" "unprognostic (4.41e-2)" FOXRED2 "ERFAD, FLJ23322" ENSG00000100350 "FAD dependent oxidoreductase domain containing 2" Q8IWF2 22 36487190-36507221 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 33.7;Kupffer cells: 33.8;Retinal pigment epithelial cells: 51.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "plasmacytoid DC: 5.3" "Lineage enriched" "Detected in many" 5 "dendritic cells: 5.3" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Macrophages, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031611, HPA031612" Approved "Intracellular and membrane" Enzyme NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 65: Brain - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 66: Non-specific - Mitochondria" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 51 "HPA031611: , HPA031612: " "unprognostic (6.43e-3)" "unprognostic (1.97e-2)" "unprognostic (1.28e-1)" "unprognostic (6.73e-2)" "unprognostic (2.26e-1)" "unprognostic (1.56e-2)" "unprognostic (3.93e-1)" "unprognostic (2.28e-3)" "unprognostic (3.25e-2)" "unprognostic (3.67e-3)" "potential prognostic favorable (6.25e-4)" "unprognostic (8.01e-2)" "unprognostic (5.34e-2)" "unprognostic (3.88e-3)" "unprognostic (1.59e-1)" "unprognostic (2.52e-1)" "unprognostic (1.53e-1)" "unprognostic (1.02e-2)" "unprognostic (1.10e-3)" "unprognostic (2.14e-3)" "unprognostic (1.77e-1)" "unprognostic (4.04e-2)" "unprognostic (3.55e-1)" "unprognostic (4.53e-2)" "unprognostic (2.63e-2)" "potential prognostic favorable (5.76e-4)" "unprognostic (5.07e-2)" "unprognostic (2.34e-2)" "unprognostic (1.42e-1)" "potential prognostic unfavorable (5.52e-5)" "unprognostic (1.89e-1)" FOXS1 "FKHL18, FREAC10" ENSG00000179772 "Forkhead box S1" O43638 20 31844303-31845604 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "blood vessel: 48.7" "Group enriched" "Detected in some" 4 "Hepatic stellate cells: 19.4;Pericytes: 40.9;Peritubular myoid cells: 53.9;Vascular smooth muscle cells: 34.3" "Cell type enhanced" "Detected in some" "fibroblast: 16.2;pericyte: 76.2;vascular associated smooth muscle cell: 34.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 9.8" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Minor Salivary Gland - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA042475 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 47: Endothelial cells - Vasculature" "Cluster 38: Non-specific - Transcription" "Cluster 110: Mural cells - ECM organization" 12 "Nucleoplasm, Cytosol" "HPA042475: " "unprognostic (9.49e-2)" "unprognostic (3.29e-1)" "unprognostic (3.17e-1)" "unprognostic (6.97e-2)" "potential prognostic unfavorable (5.51e-4)" "unprognostic (1.11e-1)" "unprognostic (1.70e-1)" "unprognostic (1.13e-1)" "unprognostic (3.34e-1)" "unprognostic (3.44e-2)" "unprognostic (7.90e-2)" "unprognostic (1.86e-2)" "potential prognostic unfavorable (5.23e-4)" "unprognostic (3.22e-2)" "unprognostic (5.14e-2)" "unprognostic (3.30e-1)" "unprognostic (3.69e-2)" "unprognostic (3.64e-1)" "unprognostic (7.34e-3)" "unprognostic (2.33e-1)" "unprognostic (7.56e-2)" "unprognostic (8.05e-2)" "unprognostic (1.00e-1)" "unprognostic (3.75e-1)" "unprognostic (7.56e-2)" "unprognostic (1.30e-2)" "unprognostic (3.85e-1)" "potential prognostic unfavorable (6.30e-4)" "unprognostic (1.58e-1)" "unprognostic (1.20e-1)" "unprognostic (5.41e-2)" FPGS ENSG00000136877 "Folylpolyglutamate synthase" Q05932 9 127794597-127814327 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "One-carbon metabolism" Ligase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050488 Approved "Intracellular and membrane" Enzyme NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 44: Non-specific - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 15: Non-specific - Protein processing" "HPA050488: " "unprognostic (7.32e-2)" "unprognostic (6.75e-2)" "unprognostic (6.84e-2)" "unprognostic (9.45e-2)" "unprognostic (1.71e-1)" "unprognostic (1.27e-2)" "unprognostic (1.30e-1)" "unprognostic (1.54e-3)" "unprognostic (2.41e-2)" "unprognostic (3.85e-1)" "unprognostic (9.84e-3)" "unprognostic (1.66e-1)" "unprognostic (5.11e-2)" "unprognostic (2.22e-1)" "unprognostic (2.05e-1)" "unprognostic (4.58e-2)" "unprognostic (1.22e-2)" "potential prognostic unfavorable (3.57e-4)" "unprognostic (2.51e-1)" "unprognostic (1.24e-1)" "unprognostic (8.12e-2)" "unprognostic (1.05e-2)" "unprognostic (1.51e-1)" "unprognostic (7.41e-2)" "unprognostic (1.52e-1)" "unprognostic (4.69e-2)" "unprognostic (4.17e-1)" "unprognostic (1.45e-1)" "unprognostic (2.04e-1)" "unprognostic (1.41e-1)" "unprognostic (1.61e-2)" FPGT GFPP ENSG00000254685 "Fucose-1-phosphate guanylyltransferase" O14772 1 74198238-74234086 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 42.3;Bergmann glia: 68.2;Brain excitatory neurons: 34.8;Brain inhibitory neurons: 28.7;Choroid plexus epithelial cells: 37.5;Ependymal cells: 57.2;Microglia: 48.0;Oligodendrocyte progenitor cells: 49.1;Oligodendrocytes: 64.3;Other brain neurons: 27.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072331 Approved Vesicles NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 22: Non-specific - Basic cellular functions" Vesicles "HPA072331: " "unprognostic (1.74e-1)" "unprognostic (3.02e-1)" "unprognostic (1.75e-1)" "unprognostic (6.98e-2)" "unprognostic (1.87e-2)" "unprognostic (5.14e-2)" "unprognostic (2.47e-1)" "unprognostic (1.02e-1)" "unprognostic (1.91e-1)" "unprognostic (6.77e-3)" "potential prognostic favorable (6.35e-7)" "unprognostic (6.21e-3)" "unprognostic (6.70e-2)" "potential prognostic unfavorable (5.85e-4)" "unprognostic (1.68e-1)" "unprognostic (2.72e-1)" "unprognostic (9.46e-2)" "unprognostic (1.59e-1)" "unprognostic (2.12e-1)" "unprognostic (2.62e-2)" "potential prognostic unfavorable (4.37e-4)" "unprognostic (1.66e-2)" "unprognostic (4.02e-1)" "unprognostic (4.06e-1)" "unprognostic (1.27e-3)" "unprognostic (2.67e-1)" "unprognostic (6.61e-2)" "unprognostic (1.64e-1)" "unprognostic (6.51e-2)" "unprognostic (7.44e-2)" "unprognostic (2.48e-1)" FPGT-TNNI3K ENSG00000259030 "FPGT-TNNI3K readthrough" 1 74198235-74544393 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 8.7" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.9;Corticotrophs: 1.2;Fibro-adipogenic progenitors: 1.3;Gastric chief cells: 1.1;Lactotrophs: 1.4;Late primary spermatocytes: 1.3;Myonuclei: 2.0;Myosatellite cells: 1.4;Thyrotrophs: 1.1" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" HPA072331 Approved Vesicles NA NA "Cluster 41: Basophils - Unknown function" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 53: Neurons - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 46: Skeletal myocytes - Muscle structure & formation" Vesicles "HPA072331: " "unprognostic (2.40e-2)" "unprognostic (1.40e-3)" "unprognostic (1.33e-2)" "unprognostic (9.95e-2)" "unprognostic (1.90e-1)" FPR1 "FMLP, FPR" ENSG00000171051 "Formyl peptide receptor 1" P21462 19 51745172-51804115 "G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 179.3;lymphoid tissue: 175.1" "Cell type enriched" "Detected in some" 7 "Neutrophils: 3550.8" "Cell type enriched" "Detected in some" 4 "central nervous system macrophage: 26.0" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 76.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 4198.3" "Lineage enriched" "Detected in many" 6 "granulocytes: 4198.3" "Low cancer specificity" "Detected in some" "Adrenal gland - Macrophages, Breast - Macrophages, Colon - Neutrophils, Kidney - Macrophages, Liver - Neutrophils, Lung - Neutrophils_2, Prostate - Macrophages, Skeletal muscle - Neutrophils, Skin - Macrophages, Spleen - Neutrophils_2" "Not detected" "Not detected" "HPA046550, HPA061744" Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 72: Neuronal - Signal transduction" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 51 "Golgi apparatus" "Nucleoplasm, Nucleoli" "HPA046550: , HPA061744: " "unprognostic (1.05e-1)" "unprognostic (9.55e-2)" "unprognostic (2.26e-1)" "unprognostic (3.81e-1)" "unprognostic (2.80e-1)" "unprognostic (2.04e-1)" "unprognostic (5.80e-2)" "unprognostic (5.94e-2)" "unprognostic (6.87e-2)" "unprognostic (1.74e-1)" "unprognostic (5.85e-3)" "unprognostic (4.38e-2)" "unprognostic (1.76e-1)" "unprognostic (1.68e-1)" "unprognostic (4.16e-2)" "unprognostic (1.59e-1)" "unprognostic (5.92e-3)" "unprognostic (2.41e-2)" "unprognostic (1.91e-1)" "unprognostic (1.63e-3)" "unprognostic (2.18e-1)" "unprognostic (4.53e-2)" "unprognostic (2.78e-1)" "unprognostic (2.96e-1)" "unprognostic (4.04e-2)" "unprognostic (5.55e-2)" "unprognostic (7.47e-2)" "unprognostic (6.93e-2)" "unprognostic (5.41e-3)" "unprognostic (5.14e-3)" "unprognostic (2.83e-1)" FPR2 "ALX, ALXR, FMLP-R-II, FMLPX, FPR2A, FPRH2, FPRL1, HM63, LXA4R" ENSG00000171049 "Formyl peptide receptor 2" P25090 19 51752026-51770531 "G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 52.9" "Cell type enriched" "Detected in some" 8 "Neutrophils: 786.9" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 1.9;miscellaneous: 2.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 10 "neutrophil: 1191.9" "Lineage enriched" "Detected in many" 10 "granulocytes: 1191.9" "Group enriched" "Detected in some" 4 "Bladder cancer: 2.8;Leukemia: 2.6;liver cancer: 2.1" "Adrenal gland - Macrophages, Colon - Neutrophils, Heart muscle - Neutrophils, Kidney - Macrophages, Liver - Neutrophils, Lung - Neutrophils_2, Prostate - Macrophages, Skeletal muscle - Neutrophils, Spleen - Neutrophils_2, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Neutrophils" "Not detected" "Not detected" HPA029154 Approved NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 58 "HPA029154: " "unprognostic (9.37e-2)" "unprognostic (2.27e-1)" "unprognostic (1.34e-1)" "unprognostic (3.38e-1)" "unprognostic (1.63e-1)" "unprognostic (3.91e-2)" "unprognostic (2.28e-1)" "unprognostic (1.17e-1)" "unprognostic (3.23e-2)" "unprognostic (4.30e-3)" "unprognostic (4.16e-2)" "unprognostic (1.47e-1)" "unprognostic (4.79e-2)" "unprognostic (3.93e-2)" "unprognostic (2.33e-3)" "unprognostic (1.70e-1)" "unprognostic (8.54e-2)" "unprognostic (5.97e-2)" "unprognostic (1.27e-1)" "unprognostic (1.08e-1)" "unprognostic (2.85e-2)" "unprognostic (1.12e-1)" "unprognostic (3.02e-1)" FPR3 "FMLPY, FPRH1, FPRL2, RMLP-R-I" ENSG00000187474 "Formyl peptide receptor 3" P25089 19 51795157-51826190 "G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 26.6" "Cell type enhanced" "Detected in some" "cDC: 304.3;Kupffer cells: 196.8;Macrophages: 236.0;monocytes: 74.5" "Cell type enriched" "Detected in some" 5 "central nervous system macrophage: 17.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 20 "classical monocyte: 2.3;intermediate monocyte: 6.7;myeloid DC: 2.4" "Group enriched" "Detected in many" 46 "dendritic cells: 2.4;monocytes: 6.7" "Cancer enriched" "Detected in some" 5 "Gastric cancer: 6.7" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid gland - Macrophages" HPA059452 Approved "Plasma membrane,Primary cilium" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 32: Non-specific - Cell proliferation" "Cluster 82: Dendritic cells - Antigen presentation" "Plasma membrane, Primary cilium" "HPA059452: " "unprognostic (1.33e-1)" "unprognostic (4.30e-2)" "unprognostic (3.10e-1)" "unprognostic (7.69e-2)" "unprognostic (3.26e-1)" "unprognostic (1.46e-1)" "unprognostic (7.03e-3)" "unprognostic (3.65e-1)" "unprognostic (2.22e-1)" "unprognostic (6.54e-2)" "unprognostic (9.26e-3)" "unprognostic (4.23e-1)" "unprognostic (1.79e-1)" "unprognostic (1.41e-1)" "unprognostic (1.19e-1)" "unprognostic (2.69e-2)" "potential prognostic unfavorable (2.57e-4)" "unprognostic (7.49e-2)" "unprognostic (1.32e-1)" "unprognostic (1.17e-2)" "unprognostic (1.78e-1)" "unprognostic (2.80e-1)" "unprognostic (9.45e-2)" "unprognostic (1.81e-1)" "unprognostic (3.16e-2)" "unprognostic (8.25e-2)" "unprognostic (3.31e-2)" "unprognostic (1.89e-1)" "unprognostic (6.49e-3)" "unprognostic (2.81e-1)" "unprognostic (8.47e-2)" FRA10AC1 C10orf4 ENSG00000148690 "FRA10A associated CGG repeat 1" Q70Z53 10 93667883-93702592 "Predicted intracellular proteins" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039204 Approved NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 17 "HPA039204: " "unprognostic (6.07e-2)" "unprognostic (1.10e-1)" "unprognostic (1.10e-2)" "unprognostic (3.41e-2)" "unprognostic (3.13e-1)" "unprognostic (6.37e-2)" "unprognostic (4.33e-2)" "unprognostic (1.25e-2)" "unprognostic (2.53e-1)" "potential prognostic favorable (8.92e-5)" "unprognostic (5.91e-3)" "unprognostic (1.33e-1)" "unprognostic (1.25e-2)" "unprognostic (3.31e-1)" "unprognostic (2.43e-2)" "unprognostic (1.73e-1)" "potential prognostic favorable (1.16e-4)" "unprognostic (2.77e-2)" "unprognostic (9.93e-2)" "unprognostic (1.06e-3)" "unprognostic (2.21e-1)" "unprognostic (1.16e-2)" "unprognostic (5.20e-2)" "unprognostic (1.12e-1)" "unprognostic (2.85e-1)" "unprognostic (1.82e-1)" "unprognostic (2.06e-1)" "unprognostic (4.07e-2)" "unprognostic (4.27e-1)" "unprognostic (5.95e-3)" FRAS1 "FLJ14927, FLJ22031, KIAA1500" ENSG00000138759 "Fraser extracellular matrix complex subunit 1" Q86XX4 4 78057323-78544269 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 11.2" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 790.3;Epicardial cells: 445.7;Loop of henle epithelial cells: 459.5;Mesothelial cells: 557.2;Pituitary stem cells: 1735.5;Prostatic glandular cells: 361.5;Proximal tubule cells: 870.9;Renal collecting duct principal cells: 654.3;Renal connecting tubule cells: 1337.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051601 Approved "Intracellular and membrane" "No annotated function" NA NA "Cluster 33: Thyroid gland - Tissue development" "Cluster 38: Sub-cortical - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 88: Proximal tubular cells - Transmembrane transport" 3 "HPA051601: " "unprognostic (6.10e-2)" "unprognostic (1.81e-1)" "unprognostic (1.65e-1)" "unprognostic (7.51e-2)" "unprognostic (2.16e-1)" "unprognostic (2.60e-1)" "unprognostic (1.54e-1)" "validated prognostic favorable (2.70e-7)" "validated prognostic favorable (1.37e-4)" "unprognostic (2.67e-1)" "unprognostic (1.73e-3)" "unprognostic (7.02e-2)" "unprognostic (8.20e-2)" "unprognostic (1.83e-1)" "unprognostic (1.69e-2)" "unprognostic (7.75e-3)" "unprognostic (4.12e-2)" "unprognostic (8.82e-2)" "unprognostic (4.98e-2)" "unprognostic (5.02e-1)" "unprognostic (4.46e-2)" "unprognostic (2.62e-2)" "unprognostic (7.11e-2)" "unprognostic (1.28e-1)" "unprognostic (9.92e-2)" "unprognostic (1.27e-3)" "unprognostic (2.53e-3)" FRAT1 ENSG00000165879 "FRAT regulator of WNT signaling pathway 1" Q92837 10 97319271-97321915 "Predicted intracellular proteins" "Wnt signaling pathway" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 37.8;Kupffer cells: 28.7;Late spermatids: 135.4;Megakaryocytes: 30.9;Monocyte progenitors: 27.3;monocytes: 30.1;Neutrophil progenitors: 32.0;Neutrophils: 91.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "eosinophil: 8.7;neutrophil: 10.1" "Lineage enriched" "Detected in many" 5 "granulocytes: 10.1" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Spleen - Neutrophils_2, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046472, HPA055258" Approved Approved Vesicles,Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 25: Non-specific - Transcription" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 9 "Vesicles, Cytosol" "CAB046472: , HPA055258: " "unprognostic (1.38e-1)" "unprognostic (1.33e-1)" "unprognostic (4.92e-2)" "potential prognostic favorable (5.92e-4)" "unprognostic (7.88e-2)" "unprognostic (2.01e-1)" "unprognostic (1.80e-1)" "unprognostic (3.73e-3)" "potential prognostic favorable (1.45e-4)" "unprognostic (1.37e-2)" "unprognostic (3.10e-3)" "unprognostic (1.55e-2)" "unprognostic (8.89e-2)" "unprognostic (2.30e-2)" "unprognostic (1.37e-2)" "unprognostic (3.21e-3)" "unprognostic (1.47e-2)" "unprognostic (1.02e-1)" "unprognostic (3.37e-2)" "unprognostic (3.42e-2)" "unprognostic (4.85e-2)" "unprognostic (9.71e-3)" "unprognostic (1.10e-2)" "unprognostic (9.78e-2)" "unprognostic (1.63e-2)" "unprognostic (1.65e-1)" "unprognostic (9.29e-2)" "unprognostic (1.00e-1)" "unprognostic (1.56e-1)" "unprognostic (1.47e-1)" "unprognostic (1.80e-3)" FRAT2 ENSG00000181274 "FRAT regulator of WNT signaling pathway 2" O75474 10 97332497-97334729 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial luminal cells: 64.0;Late spermatids: 65.1;Neutrophil progenitors: 77.4;Neutrophils: 285.7" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 4 "Testicular Germ Cell Tumor (TCGA): 107.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "eosinophil: 15.0;neutrophil: 58.4" "Lineage enriched" "Detected in all" 7 "granulocytes: 58.4" "Low cancer specificity" "Detected in all" "Lung - Neutrophils_2, Spleen - Neutrophils_2, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049763 Uncertain Approved Nucleoplasm,Mitochondria No No "Cluster 21: Neutrophils - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 2 Nucleoplasm Mitochondria "HPA049763: " "unprognostic (2.98e-2)" "unprognostic (1.01e-2)" "unprognostic (8.44e-2)" "unprognostic (3.90e-2)" "unprognostic (2.22e-1)" "unprognostic (1.36e-1)" "unprognostic (5.08e-2)" "unprognostic (2.61e-3)" "unprognostic (5.25e-2)" "unprognostic (1.89e-1)" "potential prognostic favorable (2.53e-4)" "unprognostic (7.98e-2)" "unprognostic (1.77e-1)" "unprognostic (1.20e-3)" "unprognostic (1.12e-2)" "unprognostic (2.18e-2)" "unprognostic (1.89e-1)" "unprognostic (9.35e-3)" "unprognostic (1.14e-2)" "unprognostic (1.71e-1)" "unprognostic (2.08e-1)" "unprognostic (9.45e-2)" "potential prognostic favorable (3.31e-4)" "unprognostic (5.24e-2)" "unprognostic (5.58e-3)" "unprognostic (1.40e-1)" "unprognostic (2.08e-1)" "unprognostic (3.09e-2)" "unprognostic (1.69e-1)" "unprognostic (7.12e-2)" "unprognostic (6.64e-3)" FREM1 "C9orf143, C9orf145, C9orf154, DKFZp686M16108, FLJ25461, TILRR" ENSG00000164946 "FRAS1 related extracellular matrix 1" Q5H8C1 9 14737152-14910995 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Developmental protein" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 34.4" "Cell type enhanced" "Detected in many" "Adipocytes: 199.1;Distal convoluted tubule cells: 529.0;Early spermatids: 162.0;Ependymal cells: 157.3;Fibro-adipogenic progenitors: 261.5;Hematopoietic stem cells: 182.0;Late spermatids: 202.6;Megakaryocyte progenitors: 213.0;Megakaryocyte-Erythroid progenitors: 508.4;Renal collecting duct intercalated cells: 515.6;Renal collecting duct principal cells: 201.9;Renal connecting tubule cells: 475.4" "Cell type enhanced" "Detected in all" "CGE interneuron: 258.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 4.9;Rhabdoid: 5.9" "Adrenal gland - Fibroblasts, Liver - Hepatic stellate cells, Minor Salivary Gland - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted to extracellular matrix" "Developmental protein" NA NA 7100 "Cluster 22: Epididymis - Mixed function" "Cluster 25: Non-specific - Transcription" "Cluster 47: Leukemia - Hemostasis" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" "unprognostic (2.70e-2)" "potential prognostic favorable (1.29e-4)" "unprognostic (3.25e-3)" "unprognostic (5.86e-2)" "unprognostic (5.12e-2)" "unprognostic (1.61e-1)" "unprognostic (3.65e-2)" "unprognostic (1.55e-3)" "potential prognostic favorable (2.20e-6)" "unprognostic (3.10e-2)" "unprognostic (5.29e-2)" "unprognostic (2.39e-1)" "unprognostic (2.73e-1)" "unprognostic (3.82e-3)" "unprognostic (5.18e-2)" "unprognostic (2.07e-1)" "unprognostic (6.62e-2)" "unprognostic (1.39e-1)" "unprognostic (1.25e-1)" "unprognostic (1.34e-2)" "unprognostic (1.89e-1)" "unprognostic (4.51e-2)" FREM2 DKFZp686J0811 ENSG00000150893 "FRAS1 related extracellular matrix 2" Q5SZK8 13 38687077-38887131 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 7.2;thyroid gland: 4.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 170.1;Bergmann glia: 132.3;Distal convoluted tubule cells: 214.1;Endometrial glandular cells: 78.7;Endometrial luminal cells: 114.7;Loop of henle epithelial cells: 91.6;Myonuclei: 166.3;Pituitary stem cells: 212.3;Proximal tubule cells: 134.6;Renal collecting duct principal cells: 99.7;Renal connecting tubule cells: 147.2;Thymic myoid cells: 84.3;Transitional alveolar cells: 87.1" "Cell type enhanced" "Detected in many" "Bergmann glia: 144.0;LAMP5-LHX6 and Chandelier: 73.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "testis cancer: 27.3" "Lung - Alveolar cells type 2, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA028831 Uncertain Approved Cytosol NA NA 8300000 "Cluster 72: Kidney - Transmembrane transport" "Cluster 53: Neurons - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 1 Cytosol "HPA028831: " "unprognostic (2.36e-2)" "potential prognostic unfavorable (1.27e-4)" "unprognostic (1.75e-1)" "unprognostic (3.83e-1)" "unprognostic (6.67e-2)" "unprognostic (2.38e-1)" "potential prognostic favorable (2.28e-9)" "unprognostic (1.57e-3)" "potential prognostic favorable (1.07e-5)" "unprognostic (9.60e-3)" "unprognostic (2.83e-1)" "unprognostic (3.22e-2)" "unprognostic (8.03e-3)" "unprognostic (2.56e-1)" "unprognostic (1.47e-2)" "unprognostic (2.20e-1)" "unprognostic (1.50e-1)" "unprognostic (6.91e-2)" "unprognostic (3.75e-2)" FREM3 ENSG00000183090 "FRAS1 related extracellular matrix 3" P0C091 4 143577302-143700675 "Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.2" "Cell type enhanced" "Detected in many" "Adipocytes: 22.7;Cardiomyocytes: 85.4;Epicardial cells: 36.4;Hepatic stellate cells: 12.9;Medullary thymic epithelial cells: 9.6;Myonuclei: 18.2" "Cell type enhanced" "Detected in many" "LAMP5-LHX6 and Chandelier: 24.3;upper-layer intratelencephalic: 37.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pituitary gland - Thyrotropes" "Group enriched" "Detected in some" 5 "basal ganglia: 3.1;hypothalamus: 2.8;thalamus: 4.4" HPA041641 Uncertain "Secreted to extracellular matrix" "Cell adhesion" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" "HPA041641: " "potential prognostic favorable (2.15e-4)" FRG1 "FRG1A, FSG1" ENSG00000109536 "FSHD region gene 1" Q14331 4 189940870-189963202 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing, Myogenesis, Ribosome biogenesis, rRNA processing" "Actin-binding, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 119.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075683 Approved NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 74: Non-specific - Signal transduction" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 17: Non-specific - RNA processing" 9 "HPA075683: " "unprognostic (3.07e-2)" "unprognostic (4.01e-1)" "unprognostic (5.88e-2)" "unprognostic (1.59e-3)" "unprognostic (2.16e-1)" "unprognostic (2.73e-1)" "unprognostic (1.54e-1)" "unprognostic (3.26e-1)" "unprognostic (1.71e-2)" "unprognostic (2.75e-1)" "potential prognostic favorable (2.85e-5)" "unprognostic (6.69e-2)" "unprognostic (9.03e-2)" "unprognostic (5.53e-2)" "unprognostic (1.53e-1)" "unprognostic (1.37e-1)" "unprognostic (2.04e-2)" "unprognostic (6.22e-2)" "unprognostic (2.13e-1)" "unprognostic (1.02e-1)" "unprognostic (4.64e-3)" "unprognostic (4.85e-2)" "unprognostic (2.65e-3)" "unprognostic (2.78e-1)" "unprognostic (1.68e-1)" "unprognostic (3.15e-2)" "unprognostic (1.47e-1)" "unprognostic (5.96e-3)" "unprognostic (1.57e-1)" "unprognostic (2.22e-1)" "unprognostic (2.55e-3)" FRG2 FRG2A ENSG00000205097 "FSHD region gene 2" Q64ET8 4 190024367-190027257 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Bone cancer: 4.5;Neuroblastoma: 4.8;skin cancer: 4.0;thyroid cancer: 5.3" "HPA039264, HPA047769" Uncertain NA NA "Cluster 12: Bone cancer - Neuronal signaling" "HPA039264: , HPA047769: " FRG2B ENSG00000225899 "FSHD region gene 2 family member B" Q96QU4 10 133623895-133626795 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lymphoma: 1.0" "HPA039264, HPA047769" Uncertain NA NA "Cluster 37: Neurons - Mixed function" "Cluster 50: Lymphoma - Unknown function" "HPA039264: , HPA047769: " "unprognostic (1.24e-1)" FRG2C ENSG00000172969 "FSHD region gene 2 family member C" A6NGY1 3 75664328-75667220 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "kidney: 1.4" "Group enriched" "Detected in some" 23 "Early spermatids: 17.5;Late spermatids: 40.2" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "Kidney Chromophobe (TCGA): 5.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 5.4;lymphoma: 2.1" "Testis - Late spermatids" "HPA039264, HPA047769" Uncertain NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 48: Non-specific - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" "HPA039264: , HPA047769: " "unprognostic (4.26e-2)" FRK "GTK, PTK5, RAK" ENSG00000111816 "Fyn related Src family tyrosine kinase" P42685 6 115931149-116060891 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "FDA approved drug targets, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 498.1;Distal convoluted tubule cells: 173.3;Early spermatids: 55.9;Loop of henle epithelial cells: 133.9;Oligodendrocytes: 63.0;Papillary tip epithelial cells: 77.5;Proximal tubule cells: 139.2;Renal collecting duct intercalated cells: 265.9;Renal collecting duct principal cells: 137.2;Renal connecting tubule cells: 177.7" "Group enriched" "Detected in all" 4 "choroid plexus epithelial cell: 405.1;oligodendrocyte: 103.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Minor Salivary Gland - Minor salivary glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB025217, HPA030479, HPA072590" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 9: Non-specific - Receptor signaling" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 13 Nucleoplasm Cytosol "CAB025217: , HPA030479: , HPA072590: " "unprognostic (4.65e-1)" "unprognostic (1.37e-1)" "unprognostic (2.26e-1)" "unprognostic (2.90e-2)" "unprognostic (2.03e-1)" "unprognostic (2.96e-1)" "unprognostic (2.40e-1)" "unprognostic (8.41e-2)" "potential prognostic unfavorable (6.97e-4)" "potential prognostic favorable (4.58e-7)" "unprognostic (1.21e-1)" "unprognostic (1.59e-1)" "unprognostic (9.22e-2)" "unprognostic (3.11e-1)" "unprognostic (8.42e-2)" "unprognostic (1.25e-1)" "unprognostic (2.67e-1)" "unprognostic (4.76e-2)" "unprognostic (1.21e-3)" "unprognostic (1.13e-1)" "unprognostic (7.14e-2)" "unprognostic (1.83e-1)" "unprognostic (7.48e-2)" "potential prognostic favorable (8.81e-4)" "unprognostic (6.21e-2)" "unprognostic (7.16e-2)" "unprognostic (1.81e-1)" "unprognostic (1.91e-1)" FRMD1 "bA164L23.1, DKFZp434O0117, FLJ00181, FLJ22615, FLJ40260" ENSG00000153303 "FERM domain containing 1" Q8N878 6 168053095-168101511 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 5.3;kidney: 5.5;lymphoid tissue: 9.6;stomach 1: 13.7;testis: 5.4" "Group enriched" "Detected in some" 4 "Colonocytes: 88.0;Parietal cells: 148.5;Podocytes: 166.0" "Cell type enhanced" "Detected in single" "Bergmann glia: 1.1" "Group enriched" "Detected in some" 7 "Colon Adenocarcinoma (TCGA): 3.9;Rectum Adenocarcinoma (TCGA): 4.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enterocytes, Stomach - Parietal cells" "Low region specificity" "Detected in many" HPA030347 Enhanced Approved "Actin filaments,Cytosol" NA NA "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 11: Neuronal - Sensory perception" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 1 "Actin filaments" Cytosol "HPA030347: " "unprognostic (1.63e-1)" "unprognostic (8.19e-2)" "unprognostic (1.58e-2)" "unprognostic (3.37e-2)" "unprognostic (2.83e-1)" FRMD3 "EPB41L4O, MGC20553" ENSG00000172159 "FERM domain containing 3" A2A2Y4 9 83242990-83538546 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 79.6;skeletal muscle: 76.1;tongue: 69.7" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 367.7;Corticotrophs: 823.1;Distal convoluted tubule cells: 715.2;Enterocytes: 395.9;Goblet cells: 416.9;Pericytes: 584.5;Platelets: 458.4;Podocytes: 1018.5;Proximal tubule cells: 367.1;Retinal bipolar cells: 1020.4;Retinal horizontal cells: 851.4" "Cell type enhanced" "Detected in all" "pericyte: 1293.7" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 50.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.0;intermediate monocyte: 3.4;neutrophil: 2.5;non-classical monocyte: 1.5" "Group enriched" "Detected in many" 7 "granulocytes: 2.5;monocytes: 3.4" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Minor Salivary Gland - Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017285 Approved Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 44: Non-specific - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 11 "Golgi apparatus" "Plasma membrane" "HPA017285: " "unprognostic (2.46e-1)" "unprognostic (5.50e-2)" "unprognostic (8.80e-2)" "unprognostic (9.25e-2)" "unprognostic (1.16e-1)" "unprognostic (4.29e-1)" "unprognostic (1.43e-1)" "unprognostic (1.98e-1)" "validated prognostic favorable (1.79e-8)" "validated prognostic favorable (1.46e-5)" "unprognostic (3.80e-2)" "unprognostic (2.54e-1)" "unprognostic (2.13e-2)" "unprognostic (9.03e-2)" "unprognostic (3.84e-2)" "unprognostic (1.52e-3)" "unprognostic (3.88e-2)" "unprognostic (1.64e-1)" "unprognostic (2.19e-1)" "unprognostic (2.63e-2)" "unprognostic (1.50e-2)" "unprognostic (1.92e-2)" "unprognostic (1.31e-2)" "unprognostic (7.81e-3)" "unprognostic (3.31e-1)" "unprognostic (1.62e-1)" "potential prognostic favorable (6.15e-4)" "unprognostic (2.31e-2)" FRMD4A "bA295P9.4, FLJ10210, FRMD4, KIAA1294" ENSG00000151474 "FERM domain containing 4A" Q9P2Q2 10 13643706-14462142 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 53.0" "Cell type enhanced" "Detected in many" "Adipocytes: 1054.9;Brain excitatory neurons: 1602.3;Brain inhibitory neurons: 1640.9;Microglia: 6042.4;Oligodendrocytes: 1922.0;Other brain neurons: 1235.5;Retinal amacrine cells: 1094.6;Retinal ganglion cells: 1147.2;Thyrotrophs: 975.7" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 8967.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 2.3" "Lineage enriched" "Detected in single" 5 "B-cells: 2.3" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Colon - Enteric glia cells, Liver - Vascular endothelial cells, Skeletal muscle - Endothelial cells, Spleen - Macrophages, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038449 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 51: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" "Golgi apparatus" Nucleoplasm "HPA038449: " "unprognostic (1.20e-1)" "unprognostic (2.20e-2)" "unprognostic (2.02e-2)" "unprognostic (7.53e-2)" "unprognostic (4.35e-2)" "unprognostic (2.42e-1)" "unprognostic (2.13e-1)" "potential prognostic favorable (8.47e-4)" "unprognostic (1.65e-3)" "unprognostic (1.69e-1)" "validated prognostic favorable (7.81e-4)" "validated prognostic favorable (2.99e-4)" "unprognostic (1.14e-1)" "unprognostic (2.07e-2)" "unprognostic (1.24e-2)" "unprognostic (1.68e-1)" "unprognostic (2.66e-2)" "unprognostic (1.11e-1)" "unprognostic (1.53e-1)" "unprognostic (1.05e-1)" "unprognostic (7.80e-2)" "unprognostic (1.68e-1)" "unprognostic (5.23e-2)" "unprognostic (8.30e-2)" "unprognostic (1.07e-1)" "unprognostic (3.94e-2)" "unprognostic (2.87e-1)" "unprognostic (5.52e-2)" "unprognostic (6.02e-2)" "unprognostic (3.10e-2)" "unprognostic (3.15e-1)" FRMD4B "GRSP1, KIAA1013" ENSG00000114541 "FERM domain containing 4B" Q9Y2L6 3 69168782-69542583 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 1235.9;Esophageal apical cells: 825.2;Kupffer cells: 1370.3;Macrophages: 950.7;Oligodendrocytes: 1580.4;Rod photoreceptor cells: 768.0" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 1499.9;oligodendrocyte: 1782.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pituitary gland - Undifferentiated cells (Pituitary gland)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009705 Uncertain Supported Approved "Nucleoplasm,Golgi apparatus,Centriolar satellite" NA NA 4700 "Cluster 2: Dendritic cells - Unknown function" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 11: White matter - Signal transduction" "Cluster 6: Leukemia - Signal transduction" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 2 "Centriolar satellite" "Nucleoplasm, Golgi apparatus" "HPA009705: " "unprognostic (5.27e-2)" "unprognostic (3.71e-1)" "unprognostic (3.26e-1)" "potential prognostic unfavorable (4.41e-4)" "unprognostic (1.24e-1)" "unprognostic (8.55e-2)" "unprognostic (3.38e-1)" "unprognostic (1.53e-1)" "unprognostic (3.79e-1)" "unprognostic (1.52e-2)" "validated prognostic favorable (6.88e-6)" "validated prognostic favorable (8.87e-4)" "unprognostic (2.80e-2)" "unprognostic (1.44e-1)" "unprognostic (8.45e-3)" "unprognostic (3.05e-1)" "unprognostic (4.10e-3)" "unprognostic (9.50e-2)" "unprognostic (9.53e-2)" "unprognostic (6.06e-2)" "unprognostic (9.74e-2)" "unprognostic (4.23e-3)" "unprognostic (1.99e-1)" "unprognostic (5.79e-2)" "unprognostic (2.29e-1)" "unprognostic (3.99e-1)" "unprognostic (9.32e-2)" "unprognostic (1.83e-1)" "unprognostic (1.02e-1)" "unprognostic (1.93e-1)" "unprognostic (1.87e-1)" FRMD5 MGC14161 ENSG00000171877 "FERM domain containing 5" Q7Z6J6 15 43870761-44195271 "Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 17.5;heart muscle: 43.6;retina: 18.5" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 625.2;Brain inhibitory neurons: 599.4;Müller glia: 564.5;Oligodendrocyte progenitor cells: 474.8;Oligodendrocytes: 2998.8;Pituicytes/FSCs: 956.4;Retinal amacrine cells: 1920.8;Retinal bipolar cells: 458.9;Retinal ganglion cells: 795.7;Retinal pigment epithelial cells: 567.0;Schwann cells: 899.8" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 3046.2;oligodendrocyte: 3359.4" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 15.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Pituitary gland - Undifferentiated cells (Pituitary gland), Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 72: Neuronal - Signal transduction" "Cluster 80: Oligodendrocytes - Myelination" 6 "unprognostic (2.82e-2)" "unprognostic (7.47e-2)" "unprognostic (8.99e-3)" "unprognostic (9.80e-3)" "unprognostic (6.23e-2)" "unprognostic (1.61e-1)" "potential prognostic favorable (5.16e-4)" "unprognostic (1.28e-1)" "unprognostic (3.80e-2)" "unprognostic (2.89e-2)" "unprognostic (7.36e-2)" "unprognostic (1.46e-3)" "unprognostic (1.30e-1)" "validated prognostic unfavorable (2.11e-4)" "validated prognostic unfavorable (4.28e-4)" "unprognostic (1.91e-1)" "unprognostic (6.23e-2)" "unprognostic (2.35e-1)" "unprognostic (3.43e-1)" "unprognostic (8.41e-2)" "unprognostic (1.17e-1)" "unprognostic (4.20e-2)" FRMD6 "C14orf31, EX1, MGC17921, willin" ENSG00000139926 "FERM domain containing 6" Q96NE9 14 51489100-51730727 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 452.9;Esophageal apical cells: 568.9;Esophageal basal cells: 263.4;Esophageal suprabasal cells: 537.8;Late spermatids: 769.2;Ocular epithelial cells: 333.2;Prostatic hillock cells: 406.9;Suprabasal keratinocytes: 604.3;Urothelial cells: 430.5" "Cell type enhanced" "Detected in all" "fibroblast: 617.3;pericyte: 346.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Testis - Early spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001297 Uncertain Supported Approved Mitochondria NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 16: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 69: Urothelial cells - Basic cellular functions" 28 Mitochondria "HPA001297: " "unprognostic (2.15e-2)" "unprognostic (2.46e-1)" "unprognostic (2.55e-1)" "unprognostic (9.19e-2)" "unprognostic (1.22e-1)" "unprognostic (1.91e-1)" "unprognostic (9.08e-2)" "unprognostic (2.66e-1)" "unprognostic (3.18e-1)" "unprognostic (3.40e-3)" "potential prognostic favorable (2.82e-6)" "unprognostic (4.17e-2)" "unprognostic (3.65e-3)" "unprognostic (1.53e-2)" "unprognostic (6.22e-3)" "potential prognostic unfavorable (6.56e-5)" "unprognostic (2.15e-3)" "unprognostic (3.13e-2)" "unprognostic (1.85e-1)" "unprognostic (1.23e-2)" "unprognostic (1.19e-2)" "unprognostic (3.63e-3)" "unprognostic (2.31e-2)" "unprognostic (1.97e-2)" "unprognostic (7.60e-2)" "unprognostic (4.96e-3)" "unprognostic (1.12e-1)" "potential prognostic unfavorable (6.04e-4)" "unprognostic (5.19e-2)" "unprognostic (4.48e-2)" "unprognostic (1.03e-1)" FRMD7 "FLJ43346, NYS, NYS1" ENSG00000165694 "FERM domain containing 7" Q6ZUT3 X 132076990-132128020 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" Neurogenesis "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "endometrium 1: 2.6;kidney: 2.5;smooth muscle: 2.1" "Cell type enhanced" "Detected in some" "Brain inhibitory neurons: 1.2;Cardiomyocytes: 1.6;Distal convoluted tubule cells: 2.8;Epicardial cells: 2.3;Podocytes: 1.0;Renal collecting duct intercalated cells: 6.6;Thymocytes: 2.5" "Cell type enhanced" "Detected in some" "eccentric medium spiny neuron: 14.7;fibroblast: 4.4" "Cancer enriched" "Detected in single" 23 "Kidney Chromophobe (TCGA): 4.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Intercalated cells, Liver - Hepatocytes" "Region enriched" "Detected in many" 28 "olfactory bulb: 65.7" "Region enriched" "Detected in all" 5 "olfactory bulb: 27.6" HPA000886 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 66: Non-specific - Mitochondria" "Cluster 109: Neurons - Neuronal signaling" 1 "Plasma membrane" "Nucleoplasm, Cytosol" "HPA000886: " "unprognostic (7.70e-3)" FRMD8 "FKSG44, FLJ90369, iTAP" ENSG00000126391 "FERM domain containing 8" Q9BZ67 11 65386621-65413525 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 151.6;Urothelial cells: 125.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells, Lung - Endothelial cells, Pituitary gland - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002861 Approved Approved "Nucleoplasm,Plasma membrane,Centriolar satellite,Cytosol" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 69: Urothelial cells - Basic cellular functions" 5 "Plasma membrane, Centriolar satellite" "Nucleoplasm, Cytosol" "HPA002861: " "unprognostic (1.39e-1)" "unprognostic (4.78e-2)" "unprognostic (1.29e-1)" "unprognostic (1.94e-1)" "unprognostic (1.47e-1)" "unprognostic (2.91e-2)" "unprognostic (1.21e-1)" "unprognostic (3.12e-2)" "unprognostic (2.47e-2)" "unprognostic (1.32e-1)" "unprognostic (1.80e-3)" "unprognostic (3.95e-2)" "unprognostic (9.97e-2)" "potential prognostic unfavorable (4.34e-6)" "unprognostic (8.16e-2)" "unprognostic (4.56e-3)" "potential prognostic unfavorable (6.99e-4)" "unprognostic (9.37e-2)" "unprognostic (1.49e-1)" "unprognostic (1.30e-3)" "unprognostic (3.43e-1)" "unprognostic (4.95e-3)" "unprognostic (1.41e-2)" "unprognostic (8.47e-3)" "unprognostic (1.49e-1)" "potential prognostic favorable (2.60e-4)" "unprognostic (1.98e-2)" "unprognostic (1.86e-2)" "unprognostic (6.62e-2)" "unprognostic (9.55e-2)" "unprognostic (8.60e-2)" FRMPD1 "FRMD2, KIAA0967" ENSG00000070601 "FERM and PDZ domain containing 1" Q5SYB0 9 37650954-37746904 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "retina: 63.9" "Group enriched" "Detected in many" 8 "Cone photoreceptor cells: 542.4;Retinal bipolar cells: 144.1;Rod photoreceptor cells: 409.8;Sertoli cells: 200.0" "Cell type enhanced" "Detected in many" "CGE interneuron: 48.1;LAMP5-LHX6 and Chandelier: 67.1;midbrain-derived inhibitory: 51.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.4" "Group enriched" "Detected in many" 5 "granulocytes: 3.4;NK-cells: 1.5" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Kidney - Intercalated cells, Pituitary gland - Gonadotropes, Prostate - Prostate glandular cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042934 Uncertain NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 42: Retina - Visual perception" "Cluster 38: Sub-cortical - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 79: Photoreceptor cells - Phototransduction" 1 "HPA042934: " "unprognostic (6.58e-2)" "unprognostic (4.94e-2)" "unprognostic (6.95e-2)" "unprognostic (2.18e-1)" "unprognostic (1.13e-2)" "unprognostic (2.59e-2)" "unprognostic (1.51e-1)" "unprognostic (4.01e-2)" "unprognostic (1.72e-3)" "potential prognostic unfavorable (1.17e-4)" "unprognostic (2.11e-2)" "unprognostic (1.06e-1)" "potential prognostic favorable (3.36e-4)" "unprognostic (1.18e-1)" "unprognostic (6.01e-2)" "unprognostic (6.46e-3)" "unprognostic (1.61e-1)" "unprognostic (9.05e-2)" "unprognostic (3.75e-3)" "unprognostic (4.72e-2)" "unprognostic (1.73e-1)" "unprognostic (9.93e-2)" "unprognostic (1.73e-3)" "unprognostic (3.27e-1)" "unprognostic (3.28e-2)" "unprognostic (7.44e-2)" "unprognostic (9.95e-2)" FRMPD2 "MGC35285, PDZD5C, PDZK5C" ENSG00000170324 "FERM and PDZ domain containing 2" Q68DX3 10 48153088-48274696 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "retina: 22.9" "Cell type enhanced" "Detected in many" "Astrocytes: 115.8;Bergmann glia: 130.1;Choroid plexus epithelial cells: 123.3;Cone photoreceptor cells: 399.5;Endometrial ciliated cells: 316.9;Ependymal cells: 553.8;Epididymal efferent duct ciliated cells: 170.4;Fallopian tube ciliated cells: 104.5;Late spermatids: 86.8;Respiratory ciliated cells: 231.9;Retinal bipolar cells: 121.0;Rod photoreceptor cells: 217.7" "Cell type enhanced" "Detected in many" "astrocyte: 180.6;Bergmann glia: 148.4;ependymal cell: 612.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "prostate cancer: 2.5" "Breast - Breast glandular cells, Kidney - Ascending Loop of Henle cells, Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA046389, HPA052208" Uncertain "Golgi apparatus,Vesicles" NA NA "Cluster 42: Retina - Visual perception" "Cluster 46: Brainstem - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 34: Ciliated cells - Cilia assembly & function" "Golgi apparatus, Vesicles" "HPA046389: , HPA052208: " "unprognostic (3.04e-1)" "unprognostic (1.93e-2)" FRMPD3 "KIAA1817, RP5-1070B1.1" ENSG00000147234 "FERM and PDZ domain containing 3" Q5JV73 X 107449652-107605255 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.6;ovary: 2.2;thyroid gland: 2.6" "Cell type enhanced" "Detected in many" "Astrocytes: 20.6;Brain inhibitory neurons: 19.1;Choroid plexus epithelial cells: 48.5;Cone photoreceptor cells: 26.9;Lacrimal acinar cells: 19.0;Myosatellite cells: 19.0;Ovarian stromal cells: 17.9;Pancreatic islet cells: 61.1;Pituicytes/FSCs: 27.1;Retinal amacrine cells: 21.8" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 5.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adrenal gland - Adrenal medulla cells, Pancreas - Alpha cells, Stomach - Fibroblasts, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA003164 Uncertain Uncertain Mitochondria,Cytosol NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 44: Non-specific - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" Cytosol Mitochondria "HPA003164: " "unprognostic (3.28e-2)" "unprognostic (2.66e-2)" "potential prognostic favorable (1.42e-4)" "unprognostic (2.73e-1)" "unprognostic (2.25e-1)" "unprognostic (9.77e-3)" FRMPD4 "KIAA0316, PDZD10, PDZK10" ENSG00000169933 "FERM and PDZ domain containing 4" Q14CM0 X 11822423-12724523 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 8.6;parathyroid gland: 9.6;retina: 3.9" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 702.3;Brain inhibitory neurons: 1037.7;Choroid plexus epithelial cells: 306.4;Ependymal cells: 332.8;Gonadotrophs: 210.0;Other brain neurons: 332.2;Retinal horizontal cells: 2997.1" "Cell type enhanced" "Detected in all" "deep-layer corticothalamic and 6b: 3965.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 1.6" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 3: Rhabdoid - Membrane components" "Cluster 35: Neurons - Synaptic function & neurogenesis" 1 "unprognostic (5.08e-1)" FRRS1 "SDFR2, SDR2" ENSG00000156869 "Ferric chelate reductase 1" Q6ZNA5 1 99703970-99766635 "Predicted membrane proteins" "Electron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 26.7" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 101.1;Hepatocytes: 110.0;Syncytiotrophoblasts: 77.9" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 42.3;fibroblast: 18.5" "Cancer enhanced" "Detected in all" "Bladder Urothelial Carcinoma (TCGA): 21.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "eosinophil: 12.4" "Lineage enriched" "Detected in many" 9 "granulocytes: 12.4" "Cancer enriched" "Detected in all" 8 "Gallbladder cancer: 81.2" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA017883 Approved NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 76: Non-specific - Metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 26: Keratinocytes - Keratinization" "HPA017883: " "unprognostic (2.41e-1)" "unprognostic (1.01e-1)" "unprognostic (4.24e-1)" "unprognostic (2.53e-2)" "unprognostic (2.34e-1)" "unprognostic (6.10e-2)" "unprognostic (1.42e-1)" "unprognostic (2.41e-1)" "unprognostic (2.35e-1)" "potential prognostic unfavorable (1.32e-6)" "unprognostic (1.43e-1)" "unprognostic (2.19e-2)" "unprognostic (1.72e-2)" "unprognostic (1.19e-1)" "unprognostic (1.57e-2)" "potential prognostic unfavorable (3.24e-4)" "unprognostic (4.48e-3)" "unprognostic (2.50e-1)" "unprognostic (3.03e-1)" "unprognostic (1.10e-1)" "potential prognostic unfavorable (4.70e-4)" "unprognostic (1.29e-2)" "unprognostic (1.59e-1)" "unprognostic (2.68e-1)" "unprognostic (1.41e-2)" "unprognostic (1.10e-1)" "unprognostic (1.00e-2)" "unprognostic (1.83e-1)" "unprognostic (9.19e-2)" "unprognostic (8.27e-2)" "unprognostic (1.25e-1)" FRRS1L "C9orf4, CG-6" ENSG00000260230 "Ferric chelate reductase 1 like" Q9P0K9 9 109130293-109167249 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.9" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 170.2;Bergmann glia: 78.6;Brain excitatory neurons: 191.7;Brain inhibitory neurons: 219.5;Early spermatids: 234.9;Gonadotrophs: 109.2;Lactotrophs: 128.6;Other brain neurons: 198.6;Retinal amacrine cells: 155.8;Retinal bipolar cells: 88.6;Retinal ganglion cells: 115.9;Retinal horizontal cells: 150.3;Somatotrophs: 101.3;Thyrotrophs: 101.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Neuroblastoma: 2.3" "Heart muscle - Cardiomyocytes, Pancreas - Alpha cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071086 Enhanced NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 33: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" "HPA071086: " "unprognostic (1.60e-1)" "unprognostic (7.63e-3)" "unprognostic (1.27e-1)" "unprognostic (1.29e-1)" FRS2 "FRS2A, FRS2alpha, SNT-1, SNT1" ENSG00000166225 "Fibroblast growth factor receptor substrate 2" Q8WU20 12 69470349-69579793 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038323, HPA073385" Uncertain "Plasma membrane,Cell Junctions" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 61: BICR 18 - Protein kinases" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 23 "Plasma membrane, Cell Junctions" "HPA038323: , HPA073385: " "unprognostic (2.08e-1)" "unprognostic (2.81e-1)" "unprognostic (1.45e-1)" "unprognostic (2.66e-2)" "unprognostic (9.05e-2)" "unprognostic (8.22e-2)" "unprognostic (2.80e-1)" "unprognostic (5.41e-1)" "unprognostic (5.03e-2)" "unprognostic (1.49e-3)" "potential prognostic favorable (3.27e-4)" "unprognostic (1.42e-2)" "unprognostic (3.80e-1)" "unprognostic (6.14e-2)" "unprognostic (1.66e-1)" "unprognostic (2.17e-1)" "unprognostic (2.14e-2)" "unprognostic (2.15e-1)" "unprognostic (2.33e-1)" "unprognostic (5.12e-2)" "potential prognostic unfavorable (8.47e-4)" "unprognostic (2.19e-2)" "unprognostic (7.17e-2)" "unprognostic (8.75e-2)" "unprognostic (1.76e-1)" "unprognostic (2.26e-2)" "unprognostic (6.79e-2)" "unprognostic (2.55e-1)" "unprognostic (3.30e-1)" "unprognostic (3.02e-2)" "unprognostic (2.55e-1)" FRS3 "FRS2B, FRS2beta, SNT-2" ENSG00000137218 "Fibroblast growth factor receptor substrate 3" O43559 6 41770176-41786542 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 27.8" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 21.3;Cardiomyocytes: 30.9;Epicardial cells: 116.0;Retinal ganglion cells: 19.3;Vascular endothelial cells: 20.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030162, HPA030174" Enhanced NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 1: Neurons - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 82 "HPA030162: , HPA030174: " "unprognostic (1.20e-2)" "unprognostic (7.18e-2)" "unprognostic (2.72e-1)" "unprognostic (1.79e-3)" "unprognostic (5.78e-3)" "unprognostic (1.93e-1)" "unprognostic (1.27e-1)" "unprognostic (2.41e-3)" "unprognostic (3.10e-2)" "unprognostic (1.47e-2)" "unprognostic (6.12e-2)" "unprognostic (6.21e-2)" "unprognostic (1.34e-1)" "unprognostic (1.71e-2)" "unprognostic (8.27e-2)" "unprognostic (6.18e-3)" "unprognostic (1.85e-1)" "unprognostic (1.83e-1)" "unprognostic (1.16e-1)" "unprognostic (1.77e-1)" "unprognostic (2.61e-2)" "unprognostic (2.10e-2)" "unprognostic (5.54e-2)" "unprognostic (1.02e-1)" "unprognostic (7.76e-2)" "unprognostic (3.61e-1)" "unprognostic (7.45e-2)" "unprognostic (2.81e-2)" "unprognostic (3.63e-2)" "unprognostic (2.31e-1)" "unprognostic (7.26e-2)" FRY "13CDNA73, bA37E23.1, C13orf14, CG003" ENSG00000073910 "FRY microtubule binding protein" Q5TBA9 13 31846713-32299125 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 901.4;Cone photoreceptor cells: 658.3;Monocyte progenitors: 613.2;Neutrophil progenitors: 740.8;Neutrophils: 1013.6;Podocytes: 1513.5;Vascular smooth muscle cells: 800.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "basophil: 7.7;eosinophil: 11.9;neutrophil: 8.4" "Lineage enriched" "Detected in many" 10 "granulocytes: 11.9" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Endothelial cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041635 Approved NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 35: Non-specific - DNA binding" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" "HPA041635: " "unprognostic (1.76e-3)" "unprognostic (1.07e-1)" "unprognostic (7.08e-2)" "unprognostic (3.07e-1)" "unprognostic (6.26e-3)" "unprognostic (1.05e-2)" "unprognostic (2.24e-3)" "unprognostic (1.05e-1)" "validated prognostic favorable (4.05e-6)" "validated prognostic favorable (2.38e-4)" "unprognostic (1.38e-1)" "unprognostic (1.60e-1)" "unprognostic (1.09e-1)" "unprognostic (1.65e-1)" "unprognostic (2.66e-1)" "unprognostic (1.02e-1)" "unprognostic (1.54e-1)" "unprognostic (7.21e-3)" "unprognostic (4.33e-2)" "unprognostic (5.93e-2)" "unprognostic (1.10e-1)" "unprognostic (2.76e-2)" "unprognostic (4.33e-1)" "unprognostic (1.14e-2)" "unprognostic (5.08e-2)" "unprognostic (3.33e-2)" "unprognostic (1.61e-1)" "unprognostic (1.60e-2)" FRYL "AF4p12, DKFZp686E205, KIAA0826, MOR2" ENSG00000075539 "FRY like transcription coactivator" O94915 4 48497357-48780322 "Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Goblet cells: 849.0;Oligodendrocytes: 1417.3" "Cell type enhanced" "Detected in all" "oligodendrocyte: 2067.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 13.3" "Lineage enriched" "Detected in all" 6 "granulocytes: 13.3" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031106, HPA031107" Supported Approved "Microtubules,Cytokinetic bridge,Cytosol" Yes No "Cluster 46: Basophils - Proteolysis" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 11: White matter - Signal transduction" "Cluster 47: Leukemia - Hemostasis" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 26 Cytosol "Microtubules, Cytokinetic bridge" "HPA031106: , HPA031107: " "unprognostic (1.30e-1)" "unprognostic (1.84e-1)" "unprognostic (3.67e-2)" "unprognostic (5.92e-3)" "unprognostic (6.43e-2)" "unprognostic (2.04e-2)" "unprognostic (4.88e-2)" "unprognostic (2.99e-2)" "unprognostic (3.90e-2)" "potential prognostic unfavorable (2.01e-4)" "validated prognostic favorable (1.37e-7)" "validated prognostic favorable (7.04e-5)" "unprognostic (9.50e-2)" "unprognostic (1.21e-1)" "unprognostic (2.55e-2)" "unprognostic (1.00e-2)" "unprognostic (2.22e-3)" "unprognostic (3.46e-1)" "unprognostic (2.77e-1)" "unprognostic (1.01e-2)" "unprognostic (3.41e-3)" "unprognostic (4.80e-3)" "unprognostic (1.06e-1)" "unprognostic (3.27e-1)" "potential prognostic favorable (7.14e-4)" "unprognostic (3.11e-1)" "unprognostic (1.50e-1)" "unprognostic (9.80e-2)" "unprognostic (1.99e-1)" "unprognostic (2.57e-2)" "unprognostic (1.61e-1)" FRZB "FRE, FRITZ, FRP-3, FRZB-1, FRZB-PEN, FRZB1, FZRB, hFIZ, SFRP3, SRFP3" ENSG00000162998 "Frizzled related protein" Q92765 2 182833275-182866637 "Disease related genes, Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "blood vessel: 317.3;choroid plexus: 148.5;lymphoid tissue: 83.8;retina: 312.2;tongue: 108.6" "Group enriched" "Detected in many" 8 "Müller glia: 3403.4;Retinal pigment epithelial cells: 1492.0" "Group enriched" "Detected in many" 4 "pericyte: 309.0;vascular associated smooth muscle cell: 338.7" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 78.5" "Region enriched" "Detected in all" 4 "choroid plexus: 98.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 23.1;Neuroblastoma: 12.5" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Minor Salivary Gland - Fibroblasts, Prostate - Fibroblasts, Skin - Eccrine sweat gland cells, Spleen - Fibroblasts_1" "Region enhanced" "Detected in all" "olfactory bulb: 56.9" "Low region specificity" "Detected in all" "Secreted in other tissues" "Developmental protein" NA NA 17000000 "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 11: Muller glia cells - Retinal homeostasis" 1 "unprognostic (7.51e-3)" "unprognostic (9.19e-2)" "unprognostic (3.50e-1)" "unprognostic (9.21e-2)" "unprognostic (2.18e-1)" "unprognostic (2.22e-1)" "unprognostic (2.88e-2)" "potential prognostic unfavorable (9.03e-4)" "unprognostic (3.04e-3)" "unprognostic (1.02e-1)" "unprognostic (9.10e-3)" "potential prognostic favorable (5.19e-5)" "potential prognostic unfavorable (2.38e-4)" "unprognostic (2.81e-2)" "unprognostic (7.90e-2)" "potential prognostic favorable (5.76e-4)" "unprognostic (3.80e-2)" "unprognostic (1.83e-1)" "unprognostic (1.80e-1)" "unprognostic (2.25e-1)" "unprognostic (3.08e-2)" "unprognostic (6.83e-2)" "unprognostic (6.25e-3)" "unprognostic (2.82e-1)" "unprognostic (2.90e-1)" "unprognostic (9.45e-2)" "unprognostic (1.18e-1)" "unprognostic (1.97e-2)" "unprognostic (2.01e-2)" "unprognostic (1.12e-1)" "unprognostic (2.04e-2)" FSBP ENSG00000265817 "Fibrinogen silencer binding protein" O95073 8 94378377-94436952 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "retina: 11.1" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 1.7;Cone photoreceptor cells: 4.1;Corticotrophs: 1.7;Endometrial ciliated cells: 5.6;Endometrial luminal cells: 2.1;Rod photoreceptor cells: 3.6;Sertoli cells: 3.4" "Cell type enhanced" "Detected in single" "upper rhombic lip: 1.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA025059, HPA026509" Approved Supported Nucleoplasm NA NA "Cluster 42: Retina - Visual perception" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 40: Non-specific - Unknown function" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 10 Nucleoplasm "HPA025059: , HPA026509: " "unprognostic (1.53e-2)" "unprognostic (2.09e-1)" "unprognostic (6.70e-2)" "unprognostic (1.38e-1)" "unprognostic (1.00e-1)" "unprognostic (2.13e-1)" "unprognostic (3.48e-1)" "unprognostic (8.41e-2)" "unprognostic (3.79e-2)" "unprognostic (1.20e-1)" "unprognostic (1.16e-2)" "unprognostic (3.37e-3)" "unprognostic (1.51e-1)" "unprognostic (1.09e-1)" "unprognostic (2.21e-2)" "unprognostic (1.55e-1)" "unprognostic (7.09e-2)" "unprognostic (1.63e-3)" "unprognostic (7.88e-2)" "unprognostic (2.81e-1)" "unprognostic (1.09e-2)" "unprognostic (1.54e-1)" "unprognostic (4.04e-1)" "unprognostic (1.67e-1)" "unprognostic (5.63e-2)" FSCB "C14orf155, DKFZP434F1017" ENSG00000189139 "Fibrous sheath CABYR binding protein" Q5H9T9 14 44504149-44507283 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 288 "testis: 28.7" "Group enriched" "Detected in some" 4 "Early spermatids: 341.3;Late spermatids: 1312.7" "Cell type enriched" "Detected in single" 4 "choroid plexus epithelial cell: 1.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "choroid plexus: 2.5;white matter: 1.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA003546 Supported Approved "Flagellar centriole,Mid piece,Principal piece,End piece" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 3: Choroid plexus - Cilium" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" "Flagellar centriole" "Mid piece, Principal piece, End piece" "HPA003546: " FSCN1 "FLJ38511, p55, SNL" ENSG00000075618 "Fascin actin-bundling protein 1" Q16658 7 5592816-5606655 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 189.1;Esophageal basal cells: 211.5;Esophageal suprabasal cells: 109.5;Extravillous trophoblasts: 141.5;Granulosa cells: 147.6;Hofbauer cells: 666.5;Lymphatic endothelial cells: 118.7;Suprabasal keratinocytes: 134.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "myeloid DC: 2.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Skeletal muscle - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000121, HPA005723, CAB035991, HPA050654, CAB080327" Enhanced Approved "Plasma membrane,Cytosol" NA Yes 3500000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 67: Non-specific - Unknown function" "Cluster 82: Dendritic cells - Antigen presentation" 24 "Plasma membrane, Cytosol" "CAB000121: , CAB035991: , CAB080327: , HPA005723: , HPA050654: " "unprognostic (1.69e-2)" "unprognostic (1.43e-1)" "unprognostic (1.31e-1)" "unprognostic (8.01e-3)" "unprognostic (2.62e-2)" "unprognostic (3.77e-2)" "unprognostic (2.50e-1)" "unprognostic (9.43e-2)" "unprognostic (7.13e-3)" "unprognostic (2.37e-1)" "unprognostic (3.37e-2)" "unprognostic (2.74e-1)" "unprognostic (1.37e-1)" "unprognostic (5.52e-3)" "unprognostic (1.20e-1)" "validated prognostic unfavorable (1.27e-6)" "validated prognostic unfavorable (8.95e-4)" "unprognostic (4.21e-2)" "unprognostic (3.04e-2)" "unprognostic (1.31e-1)" "unprognostic (1.02e-2)" "unprognostic (9.51e-3)" "potential prognostic unfavorable (7.69e-5)" "unprognostic (2.46e-1)" "unprognostic (3.84e-1)" "unprognostic (2.43e-1)" "unprognostic (1.03e-1)" "unprognostic (2.83e-2)" "unprognostic (4.88e-2)" "unprognostic (1.75e-3)" "unprognostic (9.77e-2)" FSCN2 "RFSN, RP30" ENSG00000186765 "Fascin actin-bundling protein 2, retinal" O14926 17 81528377-81537130 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "pancreas: 4.4;retina: 8.1" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 18.6;Epicardial cells: 6.8;Late spermatids: 4.3;Pancreatic acinar cells: 29.9;Rod photoreceptor cells: 20.5" "Cell type enhanced" "Detected in single" "Bergmann glia: 1.1" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 6.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 3.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA079270 Enhanced NA NA "Cluster 42: Retina - Visual perception" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 79: Photoreceptor cells - Phototransduction" 3 "HPA079270: " "unprognostic (1.13e-2)" "unprognostic (2.93e-1)" "unprognostic (3.91e-3)" "unprognostic (1.70e-1)" "unprognostic (2.86e-1)" "unprognostic (3.54e-2)" "unprognostic (8.45e-2)" "unprognostic (1.44e-3)" "unprognostic (1.50e-1)" "unprognostic (1.33e-2)" "unprognostic (2.19e-1)" "unprognostic (2.36e-3)" FSCN3 ENSG00000106328 "Fascin actin-bundling protein 3" Q9NQT6 7 127591409-127602144 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 173 "testis: 95.7" "Cell type enriched" "Detected in many" 10 "Late spermatids: 4216.6" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA075174 Enhanced NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 2: Neurons - Nucleosome" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" "HPA075174: " FSD1 "MGC3213, MIR1" ENSG00000105255 "Fibronectin type III and SPRY domain containing 1" Q9BTV5 19 4304598-4323843 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 34.7" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 33.1;Brain inhibitory neurons: 26.7;Differentiating spermatogonia: 21.3;Innate lymphoid cells: 26.6;NK-cells: 24.7;Oligodendrocyte progenitor cells: 16.1;Oligodendrocytes: 15.4;Other brain neurons: 31.1;Parietal cells: 15.9;Retinal ganglion cells: 15.5;Retinal horizontal cells: 14.0;Undifferentiated spermatogonia: 47.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 21.6;Testicular Germ Cell Tumor (TCGA): 20.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "MAIT T-cell: 3.6;NK-cell: 5.4;plasmacytoid DC: 1.4" "Group enriched" "Detected in many" 35 "dendritic cells: 1.4;NK-cells: 5.4;T-cells: 3.6" "Cancer enhanced" "Detected in all" "Neuroblastoma: 56.6" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043141 Supported Enhanced Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" Cytosol "HPA043141: " "unprognostic (1.70e-1)" "unprognostic (1.83e-1)" "unprognostic (1.48e-1)" "unprognostic (1.12e-2)" "potential prognostic favorable (3.78e-4)" "unprognostic (8.05e-2)" "unprognostic (1.14e-1)" "unprognostic (3.74e-1)" "unprognostic (2.20e-1)" "potential prognostic unfavorable (6.12e-4)" "unprognostic (1.90e-2)" "unprognostic (9.56e-3)" "unprognostic (5.93e-2)" FSD1L "CCDC10, CSDUFD1, FSD1CL, FSD1NL" ENSG00000106701 "Fibronectin type III and SPRY domain containing 1 like" Q9BXM9 9 105447796-105552433 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 40.1" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 848.7;Ependymal cells: 214.1;Gonadotrophs: 233.0;Rod photoreceptor cells: 308.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Endothelial cells, Prostate - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035138 Approved Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 39: Astrocytes - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 79: Photoreceptor cells - Phototransduction" "Plasma membrane" "Golgi apparatus, Vesicles" "HPA035138: " "unprognostic (6.19e-2)" "unprognostic (2.78e-1)" "unprognostic (4.10e-2)" "unprognostic (6.56e-3)" "unprognostic (6.32e-3)" "unprognostic (1.42e-1)" "unprognostic (4.26e-1)" "unprognostic (3.88e-2)" "unprognostic (2.37e-2)" "unprognostic (8.49e-2)" "unprognostic (2.29e-3)" "unprognostic (1.08e-1)" "unprognostic (8.53e-2)" "unprognostic (6.75e-2)" "unprognostic (2.42e-1)" "unprognostic (2.34e-2)" "unprognostic (1.11e-2)" "unprognostic (3.02e-1)" "unprognostic (1.01e-1)" "unprognostic (1.30e-3)" "unprognostic (1.14e-2)" "unprognostic (2.25e-2)" "unprognostic (2.41e-2)" "unprognostic (4.97e-3)" "unprognostic (4.20e-2)" "unprognostic (1.47e-1)" "unprognostic (4.75e-2)" "unprognostic (8.32e-2)" "unprognostic (7.16e-2)" "unprognostic (2.55e-1)" FSD2 "RP11-127F21, SPRYD1" ENSG00000186628 "Fibronectin type III and SPRY domain containing 2" A1L4K1 15 82755362-82806070 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 35 "heart muscle: 49.0;skeletal muscle: 144.6;tongue: 41.4" "Cell type enriched" "Detected in many" 4 "Myonuclei: 801.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA046263 Approved Cytosol NA NA "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 34: Non-specific - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 77 Cytosol "HPA046263: " "unprognostic (1.76e-1)" "unprognostic (6.84e-2)" "unprognostic (4.14e-2)" "unprognostic (1.62e-1)" "unprognostic (4.79e-3)" "unprognostic (4.10e-2)" "unprognostic (8.54e-2)" "unprognostic (1.31e-1)" "unprognostic (2.66e-2)" FSHB ENSG00000131808 "Follicle stimulating hormone subunit beta" P01225 11 30231014-30235261 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" Hormone "Cancer-related genes, Disease variant, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 271 "pituitary gland: 198.9" "Cell type enriched" "Detected in some" 76 "Gonadotrophs: 1605.8" "Cell type enhanced" "Detected in single" "upper-layer intratelencephalic: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pituitary gland - Gonadotropes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB023410, HPA069703" Enhanced "Secreted to blood" Hormone NA NA 1120000 23000 "Cluster 20: Pituitary gland - Hormone signaling" "Cluster 51: Neurons - Mixed function" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 1 "CAB023410: , HPA069703: " FSHR "FSHRO, LGR1, ODG1" ENSG00000170820 "Follicle stimulating hormone receptor" P23945 2 48962157-49154527 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "ovary: 2.6;testis: 2.1" "Cell type enhanced" "Detected in some" "Adipocytes: 26.2;Bergmann glia: 77.8;Granulosa cells: 132.2;Medullary thymic epithelial cells: 43.2;Sertoli cells: 470.2" "Group enriched" "Detected in many" 4 "Bergmann glia: 147.8;deep-layer near-projecting: 94.2;mammillary body: 193.1;thalamic excitatory: 48.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Sertoli cells" "Not detected" "Not detected" "Not detected" "Not detected" "Intracellular and membrane" Receptor NA NA "Cluster 75: Ovary - Mixed function" "Cluster 44: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 4 FSIP1 FLJ35989 ENSG00000150667 "Fibrous sheath interacting protein 1" Q8NA03 15 39588357-39782841 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 10.3;testis: 6.8" "Cell type enhanced" "Detected in many" "Ependymal cells: 234.9;Epicardial cells: 666.3;Platelets: 139.2;Salivary myoepithelial cells: 175.4" "Cell type enhanced" "Detected in all" "ependymal cell: 264.3" "Group enriched" "Detected in some" 8 "Breast Invasive Carcinoma (TCGA): 16.2;Colon Adenocarcinoma (TCGA): 9.6;Rectum Adenocarcinoma (TCGA): 5.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 4.0" "Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA041002 Uncertain Approved "Nucleoplasm,Flagellar centriole,Annulus" NA NA "Cluster 21: Testis - Mixed function" "Cluster 33: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "Nucleoplasm, Flagellar centriole, Annulus" "HPA041002: " "unprognostic (9.15e-2)" "unprognostic (1.11e-1)" "unprognostic (4.09e-2)" "potential prognostic favorable (1.92e-4)" "unprognostic (1.17e-2)" "unprognostic (3.05e-2)" "unprognostic (1.36e-3)" "unprognostic (1.15e-2)" "unprognostic (1.06e-1)" "unprognostic (1.41e-1)" FSIP2 FLJ34780 ENSG00000188738 "Fibrous sheath interacting protein 2" Q5CZC0 2 185738804-185833290 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 1.3;stomach 1: 2.4;testis: 5.0" "Cell type enhanced" "Detected in many" "Adipocytes: 83.9;Cardiomyocytes: 187.4;Early spermatids: 220.0;Epicardial cells: 166.0;Foveolar cells: 172.9;Goblet cells: 85.9;Late primary spermatocytes: 396.9" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Gallbladder cancer: 1.2" "Stomach - Gastric mucous cells, Testis - Early spermatids" "Not detected" "Not detected" "Region enriched" "Detected in single" 7 "spinal cord: 1.1" HPA036139 Approved "Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Basal body,Mid piece" Yes NA "Cluster 21: Testis - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 2 Microtubules "Cytokinetic bridge, Mitotic spindle, Primary cilium, Basal body, Mid piece" "HPA036139: " "unprognostic (6.70e-2)" "unprognostic (1.71e-2)" "unprognostic (1.80e-2)" "unprognostic (2.17e-1)" FST FS ENSG00000134363 Follistatin P19883 5 53480626-53487134 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 66.8" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 101.6;Decidual stromal cells: 50.5;Fibroblasts: 70.1;Granulosa cells: 76.2;Hepatocytes: 86.1;Pancreatic acinar cells: 46.9;Salivary basal cells: 47.0;Salivary myoepithelial cells: 54.3;Thymic myoid cells: 54.4;Undifferentiated spermatogonia: 32.6" "Cell type enhanced" "Detected in many" "miscellaneous: 7.6" "Cancer enhanced" "Detected in all" "Head and Neck Squamous Cell Carcinoma (TCGA): 97.1;Liver Hepatocellular Carcinoma (TCGA): 98.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 415.0;head and neck cancer: 203.7" "Kidney - Fibroblasts, Prostate - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA016612, CAB026025" Approved Approved Vesicles "Secreted to blood" "No annotated function" NA NA 1290000 8000000 "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 29: Forebrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 10 Vesicles "CAB026025: , HPA016612: " "unprognostic (1.02e-1)" "unprognostic (2.12e-1)" "unprognostic (2.02e-2)" "unprognostic (8.27e-3)" "unprognostic (3.96e-2)" "unprognostic (1.66e-1)" "unprognostic (1.65e-1)" "unprognostic (9.85e-2)" "potential prognostic unfavorable (2.32e-4)" "unprognostic (2.63e-2)" "unprognostic (1.63e-1)" "unprognostic (4.44e-2)" "potential prognostic unfavorable (8.56e-5)" "unprognostic (6.03e-2)" "unprognostic (6.75e-2)" "unprognostic (7.80e-3)" "unprognostic (3.13e-1)" "unprognostic (1.81e-2)" "unprognostic (5.42e-3)" "unprognostic (2.89e-2)" "unprognostic (2.25e-1)" "unprognostic (6.77e-2)" "unprognostic (2.07e-2)" "unprognostic (1.22e-1)" "unprognostic (1.54e-1)" "unprognostic (1.66e-1)" "unprognostic (2.89e-1)" "unprognostic (1.87e-3)" "unprognostic (2.32e-1)" "unprognostic (3.73e-2)" "unprognostic (5.76e-2)" FSTL1 "FRP, FSL1, OCC-1, OCC1, tsc36" ENSG00000163430 "Follistatin like 1" Q12841 3 120392293-120450993 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Heparin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 720.3;Choroid plexus epithelial cells: 250.6;Decidual stromal cells: 271.2;Extravillous trophoblasts: 591.3;Fibro-adipogenic progenitors: 342.5;Fibroblasts: 637.6;Hepatic stellate cells: 406.7;Leydig cells: 353.1;Peritubular myoid cells: 295.7" "Group enriched" "Detected in many" 6 "astrocyte: 99.4;Bergmann glia: 78.0;choroid plexus epithelial cell: 176.0;endothelial cell: 65.8;ependymal cell: 202.7;fibroblast: 152.9;pericyte: 134.4;vascular associated smooth muscle cell: 78.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 14 "basophil: 12.0" "Lineage enriched" "Detected in single" 14 "granulocytes: 12.0" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 1295.8" "Kidney - Fibroblasts, Pituitary gland - Endothelial cells, Skin - Fibroblasts_2, Spleen - Fibroblasts_1, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035251, HPA040815" Uncertain Approved "Golgi apparatus,Vesicles,Cytosol" "Secreted to blood" Other NA NA 7180000 24000000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 8: Immune cells - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 19 Vesicles "Golgi apparatus, Cytosol" "HPA035251: , HPA040815: " "unprognostic (6.62e-2)" "unprognostic (2.32e-1)" "unprognostic (4.79e-2)" "unprognostic (2.17e-3)" "unprognostic (5.87e-3)" "unprognostic (7.57e-2)" "unprognostic (8.67e-3)" "unprognostic (1.56e-3)" "unprognostic (2.50e-1)" "unprognostic (3.80e-3)" "unprognostic (5.66e-3)" "unprognostic (1.01e-1)" "unprognostic (1.51e-1)" "unprognostic (1.19e-1)" "unprognostic (1.87e-1)" "unprognostic (1.34e-1)" "unprognostic (8.22e-2)" "unprognostic (1.19e-1)" "unprognostic (3.90e-1)" "unprognostic (8.91e-3)" "unprognostic (3.01e-2)" "unprognostic (4.92e-2)" "unprognostic (2.42e-1)" "unprognostic (5.89e-2)" "unprognostic (2.32e-1)" "unprognostic (2.80e-2)" "unprognostic (1.57e-3)" "unprognostic (1.38e-2)" "unprognostic (1.55e-1)" "unprognostic (1.98e-2)" "unprognostic (1.93e-2)" FSTL3 "FLRG, FSRP" ENSG00000070404 "Follistatin like 3" O95633 19 676392-683392 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Osteogenesis, Transcription, Transcription regulation" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "Extravillous trophoblasts: 5794.9" "Cell type enhanced" "Detected in all" "astrocyte: 63.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 221.3" "Pancreas - Ductal cells, Pituitary gland - Endothelial cells, Testis - Sertoli cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB024899, HPA045378" Approved Supported Nucleoplasm "Secreted in other tissues" Transcription NA Yes 5700000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 39: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 1 Nucleoplasm "CAB024899: , HPA045378: " "unprognostic (3.27e-3)" "unprognostic (1.24e-1)" "unprognostic (9.37e-2)" "potential prognostic unfavorable (2.86e-4)" "unprognostic (3.16e-3)" "unprognostic (4.29e-2)" "potential prognostic unfavorable (1.29e-4)" "unprognostic (1.36e-1)" "unprognostic (1.34e-3)" "unprognostic (1.22e-1)" "unprognostic (1.53e-1)" "unprognostic (1.30e-1)" "unprognostic (8.20e-3)" "unprognostic (2.07e-2)" "unprognostic (4.82e-3)" "potential prognostic unfavorable (7.46e-6)" "unprognostic (1.32e-1)" "potential prognostic unfavorable (2.97e-5)" "unprognostic (3.09e-2)" "unprognostic (2.01e-3)" "unprognostic (5.36e-2)" "unprognostic (6.62e-2)" "unprognostic (1.18e-2)" "unprognostic (4.13e-2)" "unprognostic (1.76e-1)" "unprognostic (8.93e-3)" "unprognostic (1.54e-1)" "unprognostic (1.63e-2)" "unprognostic (2.90e-1)" "unprognostic (4.59e-1)" "unprognostic (1.50e-3)" FSTL4 KIAA1061 ENSG00000053108 "Follistatin like 4" Q6MZW2 5 133196455-133612541 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 180.5;Brain inhibitory neurons: 270.4;Cone photoreceptor cells: 573.4;Distal convoluted tubule cells: 196.1;Early spermatids: 164.3;Epididymal efferent duct absorptive cells: 195.7;Late spermatids: 238.7;Neutrophils: 156.4;Prostatic hillock cells: 158.6;Renal connecting tubule cells: 331.5;Retinal amacrine cells: 310.4;Retinal bipolar cells: 290.6;Retinal ganglion cells: 189.3;Thyrotrophs: 266.5" "Cell type enhanced" "Detected in all" "thalamic excitatory: 714.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 52.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045920, HPA070859" Uncertain Approved Vesicles "Secreted to blood" "No annotated function" NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" Vesicles "HPA045920: , HPA070859: " "unprognostic (2.47e-1)" "unprognostic (7.69e-3)" "unprognostic (2.90e-2)" "unprognostic (3.92e-1)" "unprognostic (1.02e-2)" "unprognostic (3.15e-1)" "unprognostic (8.36e-2)" "unprognostic (1.61e-1)" "unprognostic (2.28e-1)" "unprognostic (2.81e-2)" "unprognostic (1.41e-2)" "unprognostic (2.34e-1)" "unprognostic (3.97e-2)" "unprognostic (3.45e-2)" "unprognostic (2.62e-1)" "unprognostic (3.82e-2)" "unprognostic (3.45e-1)" "unprognostic (1.80e-2)" "unprognostic (1.58e-1)" "unprognostic (2.36e-2)" "unprognostic (3.57e-2)" "unprognostic (1.07e-1)" "unprognostic (9.83e-2)" "unprognostic (1.06e-1)" "unprognostic (4.44e-2)" "unprognostic (1.82e-1)" "unprognostic (3.17e-2)" "unprognostic (2.44e-2)" FSTL5 "DKFZp566D234, KIAA1263" ENSG00000168843 "Follistatin like 5" Q8N475 4 161383897-162164004 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 12 "brain: 44.9;retina: 87.8" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 436.1;Bergmann glia: 660.9;Brain excitatory neurons: 1052.5;Brain inhibitory neurons: 426.0;Cone photoreceptor cells: 2643.5;Corticotrophs: 594.4;Other brain neurons: 506.0;Retinal bipolar cells: 1994.2;Rod photoreceptor cells: 827.6" "Cell type enhanced" "Detected in all" "LAMP5-LHX6 and Chandelier: 2260.9;upper rhombic lip: 3379.9" "Cancer enriched" "Detected in single" 6 "Skin Cutaneous Melanoma (TCGA): 3.3" "Region enhanced" "Detected in all" "cerebellum: 151.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 14.7;Sarcoma: 23.3" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pituitary gland - Corticotropes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 76.9" "Secreted in brain" "No annotated function" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 35: Non-specific - DNA binding" "Cluster 3: Rhabdoid - Membrane components" "Cluster 2: Cerebellar granular cells - Neuronal signaling" "potential prognostic favorable (1.64e-4)" "unprognostic (6.32e-2)" "unprognostic (4.31e-3)" FTCD ENSG00000160282 "Formimidoyltransferase cyclodeaminase" O95954 21 46136160-46155579 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Histidine metabolism" "Lyase, Multifunctional enzyme, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 914.3" "Cell type enhanced" "Detected in some" "Cholangiocytes: 140.8;Early spermatids: 92.7;Hepatocytes: 556.1;Late primary spermatocytes: 127.7;Late spermatids: 184.2;Oocytes: 405.2;Proximal tubule cells: 507.4" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in many" 5 "Liver Hepatocellular Carcinoma (TCGA): 232.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 7.5" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA020073, HPA030928, HPA030929, HPA036114" Enhanced Approved "Plasma membrane,Cytosol" No NA 760000 "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 34: Non-specific - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 88: Proximal tubular cells - Transmembrane transport" 6 Cytosol "Plasma membrane" "HPA020073: , HPA030928: , HPA030929: , HPA036114: " "unprognostic (5.12e-2)" "validated prognostic favorable (2.22e-6)" "validated prognostic favorable (4.89e-4)" "potential prognostic favorable (3.32e-5)" "validated prognostic favorable (4.76e-4)" "validated prognostic favorable (2.08e-4)" "unprognostic (6.88e-2)" "unprognostic (3.71e-2)" "unprognostic (1.67e-3)" "unprognostic (1.55e-1)" "unprognostic (1.75e-1)" "unprognostic (1.78e-1)" FTCDNL1 FONG ENSG00000226124 "Formiminotransferase cyclodeaminase N-terminal like" E5RQL4 2 199760544-199851192 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 109.8;Astrocytes: 89.7;Bergmann glia: 127.8;Choroid plexus epithelial cells: 90.1;Ependymal cells: 106.4;Myonuclei: 144.8;Oligodendrocytes: 131.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Macrophages, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "HPA065748, HPA078878" Enhanced Vesicles NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 55: Myocytes - Oxidative muscle function" Vesicles "HPA065748: , HPA078878: " "unprognostic (2.45e-1)" "unprognostic (8.06e-2)" "unprognostic (3.07e-3)" "unprognostic (1.41e-1)" "unprognostic (2.29e-1)" "unprognostic (8.80e-2)" "unprognostic (2.00e-2)" "unprognostic (1.02e-2)" "potential prognostic favorable (8.61e-4)" "unprognostic (2.26e-2)" "unprognostic (2.35e-1)" "unprognostic (1.99e-2)" "unprognostic (1.78e-1)" "unprognostic (2.96e-1)" "unprognostic (2.94e-1)" "unprognostic (8.33e-2)" "unprognostic (2.04e-2)" "unprognostic (6.06e-2)" "unprognostic (4.61e-2)" "unprognostic (7.88e-2)" "unprognostic (3.38e-2)" "unprognostic (2.62e-1)" "unprognostic (5.52e-2)" "unprognostic (7.29e-2)" "unprognostic (1.00e-2)" "unprognostic (2.20e-3)" "unprognostic (1.50e-1)" FTH1 "FHC, FTH, FTHL6, PIG15, PLIF" ENSG00000167996 "Ferritin heavy chain 1" P02794 11 61959718-61967634 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Essential proteins, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Iron storage" Oxidoreductase "Cancer-related genes, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Breast lactating cells: 27164.6;cDC: 17857.5;Colonocytes: 17788.5;Enterocytes: 24665.7;Esophageal apical cells: 70832.9;Kupffer cells: 17676.6;Neutrophils: 24197.5" "Cell type enhanced" "Detected in all" "oligodendrocyte: 1714.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008623, CAB080735, CAB080736, CAB080737" Approved Supported Vesicles,Cytosol NA NA 2800000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Ribosome" "Cluster 7: Liver cancer - Metabolism" "Cluster 84: Apical squamous epithelium - Cornification" 44 Vesicles Cytosol "CAB008623: , CAB080735: , CAB080736: , CAB080737: " "unprognostic (1.98e-2)" "unprognostic (6.36e-2)" "unprognostic (1.46e-1)" "unprognostic (1.19e-1)" "unprognostic (1.30e-1)" "unprognostic (9.58e-2)" "unprognostic (3.19e-2)" "unprognostic (5.05e-3)" "potential prognostic unfavorable (7.62e-4)" "unprognostic (4.20e-3)" "potential prognostic unfavorable (1.19e-4)" "unprognostic (6.80e-3)" "unprognostic (2.87e-2)" "validated prognostic unfavorable (3.05e-4)" "validated prognostic unfavorable (1.12e-4)" "unprognostic (1.91e-2)" "unprognostic (3.41e-2)" "unprognostic (9.69e-2)" "unprognostic (1.76e-2)" "unprognostic (2.11e-1)" "unprognostic (1.99e-1)" "unprognostic (1.47e-2)" "unprognostic (9.86e-3)" "unprognostic (8.00e-2)" "unprognostic (1.32e-1)" "unprognostic (6.98e-2)" "unprognostic (2.09e-1)" "unprognostic (1.98e-1)" "unprognostic (1.74e-1)" "unprognostic (3.31e-1)" "unprognostic (6.70e-2)" FTHL17 CT38 ENSG00000132446 "Ferritin heavy chain like 17" Q9BXU8 X 31071233-31072041 "Predicted intracellular proteins" "Iron storage" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 34 "testis: 3.8" "Cell type enriched" "Detected in some" 6 "Early primary spermatocytes: 17.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 3.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Gastric cancer: 3.0" "Not detected" "Not detected" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 66: Non-specific - Mitochondria" "Cluster 3: Early primary spermatocytes - Early meiosis" 3 "unprognostic (3.65e-1)" "unprognostic (1.44e-1)" "unprognostic (5.41e-2)" FTL "MGC71996, NBIA3" ENSG00000087086 "Ferritin light chain" P02792 19 48965309-48966879 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Iron storage" "Cancer-related genes, Cataract, Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 14257.7" "Group enriched" "Detected in all" 4 "Hofbauer cells: 84949.6;Kupffer cells: 144496.8" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 1112.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "granulocytes: 125828.8;monocytes: 102246.5" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Macrophages, Minor Salivary Gland - Macrophages, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020769, HPA041602" Enhanced Approved Cytosol NA NA 38000000 "Cluster 29: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 27: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 123 Cytosol "CAB020769: , HPA041602: " "unprognostic (3.14e-1)" "unprognostic (1.25e-1)" "unprognostic (4.68e-2)" "unprognostic (3.77e-3)" "unprognostic (1.71e-1)" "unprognostic (4.44e-2)" "unprognostic (3.03e-2)" "unprognostic (2.06e-2)" "unprognostic (2.72e-2)" "unprognostic (1.55e-1)" "unprognostic (1.44e-2)" "unprognostic (1.18e-1)" "unprognostic (1.01e-1)" "potential prognostic unfavorable (4.85e-4)" "unprognostic (1.35e-1)" "unprognostic (1.25e-1)" "unprognostic (6.66e-2)" "unprognostic (1.48e-1)" "unprognostic (4.16e-2)" "unprognostic (1.03e-2)" "unprognostic (1.96e-2)" "unprognostic (2.07e-1)" "unprognostic (2.50e-1)" "unprognostic (1.56e-1)" "unprognostic (9.84e-2)" "unprognostic (6.87e-3)" "unprognostic (9.80e-2)" "unprognostic (1.62e-1)" "unprognostic (4.15e-2)" "unprognostic (9.63e-3)" "unprognostic (2.01e-2)" FTMT MtF ENSG00000181867 "Ferritin mitochondrial" Q8N4E7 5 121851882-121852833 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Iron storage" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 486 "testis: 48.6" "Group enriched" "Detected in some" 5 "Early spermatids: 822.4;Late primary spermatocytes: 489.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 65: Non-specific - Unknown function" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" FTO "ALKBH9, KIAA1752, MGC5149" ENSG00000140718 "FTO alpha-ketoglutarate dependent dioxygenase" Q9C0B1 16 53701692-54158512 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase, Transferase" "Disease variant, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Respiratory ciliated cells: 2047.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017123, HPA041086, HPA068695" Enhanced Supported Vesicles,Cytosol No No 1200000 "Cluster 16: Non-specific - Cell proliferation" "Cluster 36: Brain & Liver - Signaling" "Cluster 31: Non-specific - Transcription" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 107: Ciliated cells - Cilia assembly & function" 9 Cytosol Vesicles "CAB017123: , HPA041086: , HPA068695: " "unprognostic (2.04e-1)" "unprognostic (3.19e-2)" "unprognostic (2.98e-1)" "unprognostic (2.52e-1)" "unprognostic (1.84e-1)" "unprognostic (2.97e-2)" "unprognostic (3.87e-1)" "unprognostic (9.48e-2)" "unprognostic (6.33e-2)" "unprognostic (3.69e-2)" "potential prognostic favorable (9.43e-6)" "unprognostic (1.78e-1)" "unprognostic (4.68e-2)" "unprognostic (2.19e-3)" "unprognostic (2.00e-1)" "unprognostic (1.07e-2)" "unprognostic (1.20e-1)" "unprognostic (2.67e-2)" "unprognostic (1.05e-1)" "unprognostic (1.00e-2)" "unprognostic (1.38e-3)" "unprognostic (1.97e-2)" "unprognostic (3.31e-1)" "unprognostic (1.15e-1)" "unprognostic (2.08e-1)" "unprognostic (9.74e-2)" "unprognostic (1.50e-2)" "unprognostic (1.78e-3)" "unprognostic (1.48e-1)" "unprognostic (4.47e-3)" "unprognostic (5.06e-2)" FTSJ1 "CDLIV, JM23, MRX44, MRX9, SPB1, TRM7, TRMT7" ENSG00000068438 "FtsJ RNA 2'-O-methyltransferase 1" Q9UET6 X 48476021-48486364 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 51.9;Late spermatids: 120.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002718 Approved Supported Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 54: Non-specific - Ribosome" "Cluster 14: Neurons - Synaptic function" "Cluster 36: Non-specific - mRNA processing" "Cluster 8: Non-specific - Secretory pathway" 5 Cytosol "HPA002718: " "unprognostic (2.36e-2)" "potential prognostic unfavorable (4.53e-4)" "unprognostic (1.41e-1)" "unprognostic (7.44e-2)" "unprognostic (8.90e-2)" "unprognostic (9.22e-2)" "unprognostic (1.75e-1)" "potential prognostic favorable (3.29e-4)" "unprognostic (1.70e-1)" "unprognostic (1.04e-2)" "potential prognostic favorable (1.38e-5)" "unprognostic (1.22e-3)" "unprognostic (1.79e-1)" "potential prognostic unfavorable (2.25e-5)" "unprognostic (2.25e-2)" "unprognostic (2.76e-2)" "unprognostic (6.75e-3)" "unprognostic (2.61e-2)" "unprognostic (1.64e-1)" "unprognostic (1.60e-1)" "unprognostic (3.60e-1)" "unprognostic (5.29e-3)" "unprognostic (1.08e-2)" "unprognostic (1.79e-1)" "unprognostic (3.61e-2)" "unprognostic (4.41e-2)" "unprognostic (2.49e-1)" "unprognostic (3.74e-1)" "unprognostic (6.47e-2)" "unprognostic (2.54e-1)" "unprognostic (1.75e-1)" FTSJ3 SPB1 ENSG00000108592 "FtsJ RNA 2'-O-methyltransferase 3" Q8IY81 17 63819433-63830012 "Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055544, HPA062628" Supported Enhanced "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 13: Non-specific - Mitochondria" "Cluster 49: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 27: Breast cancer - Unknown function" "Cluster 17: Non-specific - RNA processing" 133 "Nucleoli, Nucleoli rim" "Mitotic chromosome" "HPA055544: , HPA062628: " "unprognostic (1.01e-1)" "unprognostic (2.94e-1)" "unprognostic (1.70e-1)" "unprognostic (1.37e-1)" "unprognostic (1.13e-1)" "unprognostic (1.46e-1)" "unprognostic (6.49e-2)" "unprognostic (1.92e-3)" "unprognostic (1.04e-1)" "unprognostic (7.42e-3)" "unprognostic (1.65e-3)" "unprognostic (5.49e-2)" "unprognostic (7.74e-2)" "potential prognostic unfavorable (1.16e-5)" "unprognostic (1.27e-3)" "unprognostic (4.01e-3)" "potential prognostic unfavorable (1.66e-5)" "unprognostic (1.34e-1)" "unprognostic (4.80e-3)" "unprognostic (1.11e-1)" "unprognostic (1.73e-1)" "unprognostic (1.45e-1)" "unprognostic (3.13e-1)" "unprognostic (5.80e-2)" "unprognostic (4.15e-3)" "unprognostic (6.31e-2)" "unprognostic (2.09e-1)" "unprognostic (1.28e-1)" "unprognostic (3.34e-1)" "unprognostic (7.24e-2)" "unprognostic (1.70e-1)" FUBP1 "FBP, FUBP" ENSG00000162613 "Far upstream element binding protein 1" Q96AE4 1 77944055-77979110 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006149 Supported Enhanced Nucleoplasm NA NA 27000 "Cluster 33: Non-specific - ATP binding" "Cluster 49: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 37 Nucleoplasm "HPA006149: " "unprognostic (3.40e-1)" "unprognostic (4.09e-2)" "unprognostic (9.19e-2)" "unprognostic (1.61e-3)" "potential prognostic favorable (9.41e-4)" "unprognostic (2.85e-2)" "unprognostic (2.92e-1)" "unprognostic (4.46e-3)" "unprognostic (4.78e-2)" "unprognostic (7.18e-3)" "potential prognostic favorable (6.03e-4)" "unprognostic (4.82e-3)" "unprognostic (7.51e-3)" "potential prognostic unfavorable (2.25e-7)" "unprognostic (2.22e-1)" "potential prognostic unfavorable (6.58e-4)" "unprognostic (1.68e-2)" "unprognostic (1.61e-1)" "unprognostic (1.66e-1)" "unprognostic (3.00e-1)" "unprognostic (1.87e-1)" "unprognostic (3.17e-3)" "unprognostic (1.65e-2)" "unprognostic (1.30e-1)" "unprognostic (6.15e-2)" "unprognostic (2.26e-2)" "unprognostic (2.11e-1)" "unprognostic (1.50e-1)" "unprognostic (2.17e-1)" "unprognostic (2.44e-1)" "unprognostic (4.81e-2)" FUBP3 FBP3 ENSG00000107164 "Far upstream element binding protein 3" Q96I24 9 130578965-130638352 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047658, HPA058392" Approved Approved Nucleoplasm,Cytosol NA NA 6900000 "Cluster 30: Non-specific - DNA binding" "Cluster 61: Non-specific - Transcription" "Cluster 19: Astrocytes - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 17: Non-specific - RNA processing" 31 Nucleoplasm Cytosol "HPA047658: , HPA058392: " "unprognostic (1.61e-1)" "unprognostic (3.10e-2)" "unprognostic (8.05e-2)" "unprognostic (1.31e-1)" "unprognostic (1.04e-1)" "potential prognostic unfavorable (8.97e-4)" "unprognostic (5.18e-3)" "unprognostic (9.48e-2)" "unprognostic (2.19e-2)" "unprognostic (2.26e-1)" "potential prognostic favorable (1.39e-6)" "unprognostic (9.87e-3)" "unprognostic (3.58e-1)" "unprognostic (1.72e-2)" "unprognostic (2.60e-3)" "unprognostic (3.61e-3)" "unprognostic (1.06e-1)" "unprognostic (2.07e-1)" "potential prognostic favorable (7.81e-4)" "unprognostic (6.55e-2)" "unprognostic (3.12e-2)" "unprognostic (2.19e-1)" "unprognostic (9.25e-2)" "unprognostic (1.03e-1)" "unprognostic (8.63e-2)" "unprognostic (1.07e-1)" "unprognostic (7.25e-3)" "unprognostic (5.61e-3)" "unprognostic (2.67e-1)" "unprognostic (1.55e-1)" "unprognostic (3.70e-2)" FUCA1 ENSG00000179163 "Alpha-L-fucosidase 1" P04066 1 23845077-23868290 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" "Glycosidase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 187.6;Cytotrophoblasts: 240.8;Enterocytes: 209.3;Fallopian tube ciliated cells: 173.3;Hofbauer cells: 180.2;Kupffer cells: 250.1;Syncytiotrophoblasts: 250.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Lung - Macrophages, Pancreas - Macrophages, Spleen - Macrophages, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046542, HPA056371" Enhanced Supported Vesicles "Intracellular and membrane" Enzyme NA NA 40000000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 22: Epididymis - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 15: Kidney cancer - Membrane components" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 5 Vesicles "HPA046542: , HPA056371: " "potential prognostic favorable (1.91e-4)" "unprognostic (1.07e-1)" "unprognostic (1.07e-1)" "unprognostic (4.05e-1)" "unprognostic (1.03e-3)" "unprognostic (1.26e-1)" "validated prognostic unfavorable (4.30e-4)" "validated prognostic unfavorable (6.52e-5)" "unprognostic (8.57e-3)" "unprognostic (2.48e-1)" "validated prognostic favorable (0.00e+0)" "validated prognostic favorable (9.82e-4)" "potential prognostic favorable (8.64e-6)" "unprognostic (2.82e-2)" "unprognostic (4.62e-2)" "unprognostic (2.13e-3)" "unprognostic (2.59e-1)" "unprognostic (2.11e-1)" "unprognostic (3.52e-1)" "unprognostic (4.89e-2)" "unprognostic (1.70e-2)" "unprognostic (1.78e-1)" "unprognostic (4.87e-2)" "unprognostic (1.29e-1)" "unprognostic (1.11e-1)" "unprognostic (1.20e-1)" "unprognostic (1.02e-1)" "unprognostic (2.81e-1)" "unprognostic (2.34e-1)" "unprognostic (9.14e-2)" "unprognostic (4.93e-2)" FUCA2 "dJ20N2.5, MGC1314" ENSG00000001036 "Alpha-L-fucosidase 2" Q9BTY2 6 143494812-143511720 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 155.6" "Cell type enhanced" "Detected in all" "Decidual stromal cells: 152.4;Extravillous trophoblasts: 157.7;Hofbauer cells: 138.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skin - Fibroblasts_2, Spleen - Macrophages, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031659, HPA031661" Approved "Secreted to blood" Enzyme NA NA 59000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 28: Non-specific - Nuclear processes" "Cluster 8: Non-specific - Secretory pathway" 16 "HPA031659: , HPA031661: " "unprognostic (2.26e-1)" "unprognostic (2.17e-3)" "unprognostic (4.68e-3)" "unprognostic (2.13e-2)" "unprognostic (2.22e-2)" "unprognostic (3.53e-3)" "unprognostic (9.04e-2)" "potential prognostic unfavorable (4.74e-4)" "unprognostic (3.44e-2)" "unprognostic (2.31e-3)" "potential prognostic favorable (2.26e-4)" "unprognostic (1.63e-1)" "unprognostic (7.58e-2)" "validated prognostic unfavorable (1.55e-10)" "validated prognostic unfavorable (6.24e-8)" "potential prognostic unfavorable (5.33e-5)" "unprognostic (3.46e-2)" "unprognostic (6.11e-2)" "unprognostic (5.08e-3)" "unprognostic (3.84e-3)" "unprognostic (1.24e-1)" "unprognostic (2.17e-1)" "unprognostic (3.58e-1)" "unprognostic (1.98e-1)" "unprognostic (1.47e-1)" "unprognostic (1.10e-3)" "unprognostic (2.92e-1)" "unprognostic (6.97e-2)" "unprognostic (1.28e-1)" "unprognostic (7.66e-2)" "unprognostic (7.93e-2)" FUNDC1 MGC51029 ENSG00000069509 "FUN14 domain containing 1" Q8IVP5 X 44523639-44542859 "Predicted intracellular proteins" Autophagy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Megakaryocytes: 111.3;Oocytes: 115.1;Parietal cells: 192.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038773 Uncertain NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 35: Non-specific - Mixed function" "Cluster 45: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 97: Non-specific - Cellular respiration" 20 "HPA038773: " "unprognostic (9.69e-2)" "unprognostic (1.95e-2)" "unprognostic (1.73e-1)" "unprognostic (1.96e-2)" "unprognostic (7.14e-2)" "unprognostic (1.30e-1)" "unprognostic (2.35e-2)" "unprognostic (8.33e-3)" "unprognostic (7.59e-3)" "unprognostic (1.29e-3)" "potential prognostic favorable (5.99e-5)" "unprognostic (2.76e-1)" "unprognostic (1.24e-1)" "potential prognostic unfavorable (2.22e-4)" "unprognostic (6.01e-3)" "unprognostic (8.48e-2)" "unprognostic (1.07e-1)" "potential prognostic favorable (8.72e-5)" "unprognostic (4.56e-1)" "unprognostic (9.49e-3)" "unprognostic (8.19e-2)" "unprognostic (4.32e-2)" "unprognostic (2.71e-1)" "unprognostic (1.64e-1)" "unprognostic (2.90e-1)" "unprognostic (5.27e-2)" "unprognostic (1.51e-1)" "unprognostic (1.27e-1)" "unprognostic (2.41e-2)" "unprognostic (1.00e-2)" "unprognostic (9.31e-2)" FUNDC2 "DC44, HCBP6" ENSG00000165775 "FUN14 domain containing 2" Q9BWH2 X 155025980-155060304 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 18.2" "Cell type enriched" "Detected in many" 7 "Late spermatids: 2446.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059129 Approved NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 45: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 45 "HPA059129: " "unprognostic (1.31e-1)" "unprognostic (2.94e-2)" "unprognostic (1.18e-2)" "unprognostic (6.25e-2)" "unprognostic (1.04e-1)" "unprognostic (1.46e-1)" "unprognostic (1.53e-1)" "unprognostic (6.59e-3)" "unprognostic (2.17e-2)" "unprognostic (7.38e-3)" "potential prognostic favorable (2.10e-7)" "unprognostic (3.94e-3)" "unprognostic (2.69e-1)" "validated prognostic unfavorable (2.29e-4)" "validated prognostic unfavorable (5.74e-5)" "unprognostic (3.25e-1)" "unprognostic (3.74e-3)" "unprognostic (4.04e-2)" "unprognostic (9.23e-2)" "unprognostic (2.61e-2)" "unprognostic (5.15e-2)" "potential prognostic favorable (7.82e-5)" "unprognostic (2.21e-2)" "unprognostic (3.06e-1)" "unprognostic (7.70e-3)" "unprognostic (1.28e-2)" "unprognostic (8.01e-2)" "unprognostic (7.42e-2)" "unprognostic (1.03e-1)" "unprognostic (3.31e-1)" "unprognostic (1.05e-1)" FUOM "C10orf125, FLJ26016, FucM, FucU" ENSG00000148803 "Fucose mutarotase" A2VDF0 10 133355158-133358025 "Enzymes, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 233.2" "Cell type enhanced" "Detected in many" "Enterocytes: 629.7;Gastric progenitor cells: 129.4;Hepatocytes: 662.8;Hofbauer cells: 214.1;Kupffer cells: 104.5" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 9.7" "Cancer enriched" "Detected in all" 4 "Liver Hepatocellular Carcinoma (TCGA): 145.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039207 Approved NA NA 310000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 44: Non-specific - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 93: Hepatocytes - Bile production & excretion" 1 "HPA039207: " "unprognostic (3.84e-3)" "unprognostic (8.61e-3)" "unprognostic (5.50e-2)" "unprognostic (5.49e-2)" "unprognostic (7.60e-3)" "unprognostic (2.71e-1)" "unprognostic (3.00e-3)" "unprognostic (2.68e-2)" "unprognostic (1.95e-1)" "unprognostic (4.45e-3)" "unprognostic (1.41e-2)" "unprognostic (4.48e-2)" "unprognostic (4.16e-2)" "unprognostic (9.75e-2)" "unprognostic (7.98e-2)" "unprognostic (1.05e-1)" "unprognostic (1.97e-1)" "unprognostic (1.04e-1)" "unprognostic (7.27e-2)" "unprognostic (2.43e-2)" "potential prognostic unfavorable (4.42e-5)" "unprognostic (4.89e-2)" "unprognostic (9.14e-2)" "unprognostic (9.11e-2)" "unprognostic (1.32e-1)" "unprognostic (2.74e-3)" "unprognostic (2.89e-2)" "unprognostic (1.39e-2)" "unprognostic (2.61e-1)" FURIN "FUR, PACE, PCSK3, SPC1" ENSG00000140564 "Furin, paired basic amino acid cleaving enzyme" P09958 15 90868588-90883564 "Enzymes, Plasma proteins, Predicted membrane proteins" "Host-virus interaction" "Heparin-binding, Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 196.7;salivary gland: 207.7" "Cell type enhanced" "Detected in many" "Hepatocytes: 147.7;Neutrophils: 132.5;Platelets: 217.2;Salivary acinar cells: 200.1;Syncytiotrophoblasts: 119.0;Tuft cells: 276.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast), Prostate - Prostate glandular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009499, HPA067869" Enhanced Supported "Nucleoplasm,Golgi apparatus" "Intracellular and membrane" Enzyme NA NA 87000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 70: Non-specific - Protein processing" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 34 "Golgi apparatus" Nucleoplasm "CAB009499: , HPA067869: " "unprognostic (6.51e-2)" "unprognostic (2.88e-1)" "unprognostic (1.15e-1)" "unprognostic (1.69e-3)" "unprognostic (2.91e-3)" "unprognostic (1.17e-1)" "unprognostic (2.45e-2)" "unprognostic (6.10e-2)" "unprognostic (1.34e-1)" "unprognostic (2.12e-1)" "potential prognostic favorable (2.02e-5)" "unprognostic (4.99e-3)" "unprognostic (3.55e-1)" "unprognostic (7.68e-2)" "unprognostic (1.03e-1)" "unprognostic (1.11e-2)" "unprognostic (4.35e-2)" "unprognostic (2.66e-2)" "unprognostic (3.59e-1)" "unprognostic (1.85e-2)" "unprognostic (1.34e-1)" "unprognostic (3.75e-1)" "unprognostic (1.09e-1)" "unprognostic (9.31e-2)" "unprognostic (2.13e-2)" "unprognostic (1.78e-1)" "unprognostic (4.59e-1)" "unprognostic (1.25e-1)" "unprognostic (8.04e-2)" "unprognostic (4.81e-3)" "unprognostic (8.70e-2)" FUS "ALS6, FUS1, hnRNP-P2, HNRNPP2, TLS" ENSG00000089280 "FUS RNA binding protein" P35637 16 31180138-31191605 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA-binding, RNA-binding" "Amyotrophic lateral sclerosis, Cancer-related genes, Disease variant, Neurodegeneration, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008784, CAB033036, CAB058691" Supported Supported Nucleoplasm NA NA 250000 "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 20: Non-specific - Transcription regulation" 198 Nucleoplasm "CAB033036: , CAB058691: , HPA008784: " "unprognostic (5.27e-2)" "unprognostic (1.72e-1)" "unprognostic (4.91e-3)" "unprognostic (4.83e-3)" "unprognostic (3.43e-1)" "unprognostic (2.78e-1)" "unprognostic (2.58e-1)" "unprognostic (3.85e-1)" "unprognostic (7.72e-2)" "unprognostic (1.10e-1)" "potential prognostic favorable (4.03e-6)" "unprognostic (4.57e-2)" "unprognostic (1.40e-1)" "unprognostic (3.28e-3)" "potential prognostic unfavorable (7.37e-4)" "unprognostic (2.91e-2)" "unprognostic (2.66e-3)" "unprognostic (6.84e-2)" "unprognostic (5.92e-2)" "unprognostic (7.53e-2)" "unprognostic (7.61e-3)" "unprognostic (9.77e-2)" "unprognostic (1.98e-3)" "unprognostic (2.90e-3)" "unprognostic (2.73e-1)" "unprognostic (1.03e-1)" "unprognostic (2.87e-1)" "unprognostic (2.10e-1)" "unprognostic (7.14e-2)" "unprognostic (4.92e-1)" "unprognostic (4.06e-2)" FUT1 "H, HSC" ENSG00000174951 "Fucosyltransferase 1 (H blood group)" P19526 19 48748011-48755390 "Blood group antigen proteins, Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" "Blood group antigen, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 31.7;stomach 1: 15.7" "Cell type enhanced" "Detected in many" "cDC: 13.6;Erythrocyte progenitors: 17.8;Mucous neck cells: 26.4;Ocular epithelial cells: 9.9;Pancreatic acinar cells: 25.9;Parietal cells: 51.3;Platelets: 12.7;Vascular endothelial cells: 10.5" "Cell type enhanced" "Detected in some" "endothelial cell: 4.4;upper rhombic lip: 3.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Breast - Adipocytes (Breast), Liver - Vascular endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 2: Neurons - Nucleosome" "Cluster 47: Leukemia - Hemostasis" "Cluster 97: Non-specific - Cellular respiration" 11 "unprognostic (2.63e-1)" "unprognostic (1.96e-3)" "unprognostic (2.09e-1)" "unprognostic (3.52e-1)" "unprognostic (1.92e-2)" "unprognostic (1.09e-3)" "unprognostic (1.30e-1)" "unprognostic (2.47e-1)" "unprognostic (9.84e-2)" "validated prognostic favorable (1.77e-7)" "validated prognostic favorable (3.41e-6)" "unprognostic (5.94e-2)" "unprognostic (4.88e-2)" "unprognostic (1.04e-1)" "potential prognostic favorable (4.13e-5)" "unprognostic (1.55e-2)" "unprognostic (1.87e-1)" "unprognostic (7.60e-2)" "unprognostic (1.99e-1)" "unprognostic (1.42e-1)" "unprognostic (1.73e-2)" "unprognostic (1.56e-1)" "unprognostic (2.65e-1)" "unprognostic (2.37e-1)" "unprognostic (1.63e-1)" "unprognostic (5.88e-2)" "unprognostic (1.14e-1)" "unprognostic (7.48e-2)" "unprognostic (9.83e-2)" "unprognostic (6.34e-2)" FUT10 ENSG00000172728 "Fucosyltransferase 10" Q6P4F1 8 33370824-33473146 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Early spermatids: 234.4;Late primary spermatocytes: 165.1;Late spermatids: 433.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053970, HPA058655" Uncertain Approved "Nucleoplasm,Endoplasmic reticulum,Golgi apparatus" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 40: Non-specific - Unknown function" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" "Nucleoplasm, Endoplasmic reticulum, Golgi apparatus" "HPA053970: , HPA058655: " "unprognostic (3.41e-2)" "unprognostic (1.37e-1)" "unprognostic (5.63e-3)" "unprognostic (6.21e-2)" "unprognostic (2.34e-3)" "unprognostic (1.20e-1)" "unprognostic (5.10e-1)" "unprognostic (5.87e-3)" "unprognostic (6.63e-2)" "unprognostic (6.02e-2)" "potential prognostic favorable (7.51e-6)" "unprognostic (4.84e-2)" "unprognostic (9.55e-2)" "unprognostic (1.57e-1)" "unprognostic (9.49e-2)" "unprognostic (9.94e-2)" "unprognostic (4.25e-2)" "unprognostic (8.12e-3)" "unprognostic (1.06e-1)" "unprognostic (9.93e-2)" "unprognostic (1.26e-2)" "unprognostic (9.43e-2)" "unprognostic (3.27e-3)" "unprognostic (9.15e-3)" "unprognostic (1.08e-2)" "unprognostic (7.19e-2)" "unprognostic (2.41e-1)" "unprognostic (1.24e-1)" "unprognostic (2.72e-3)" "unprognostic (1.99e-1)" FUT11 MGC33202 ENSG00000196968 "Fucosyltransferase 11" Q495W5 10 73772276-73780251 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Early spermatids: 225.5;Esophageal apical cells: 254.1;Late spermatids: 371.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014033 Approved Approved "Nuclear membrane,Golgi apparatus" "Intracellular and membrane" Enzyme NA NA 560000 "Cluster 15: NK-cells - Unknown function" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 84: Apical squamous epithelium - Cornification" 2 "Nuclear membrane" "Golgi apparatus" "HPA014033: " "unprognostic (3.15e-2)" "unprognostic (3.84e-2)" "unprognostic (2.41e-1)" "potential prognostic unfavorable (1.45e-4)" "unprognostic (1.60e-1)" "unprognostic (8.05e-2)" "unprognostic (6.52e-2)" "unprognostic (1.07e-1)" "unprognostic (1.00e-1)" "unprognostic (2.62e-2)" "potential prognostic favorable (9.09e-8)" "unprognostic (1.65e-3)" "unprognostic (7.65e-2)" "unprognostic (2.83e-3)" "unprognostic (3.47e-2)" "unprognostic (5.89e-2)" "unprognostic (1.77e-2)" "unprognostic (1.57e-2)" "unprognostic (2.23e-1)" "unprognostic (6.04e-2)" "potential prognostic unfavorable (8.35e-5)" "unprognostic (4.92e-2)" "unprognostic (5.42e-3)" "unprognostic (1.38e-1)" "unprognostic (1.03e-1)" "unprognostic (1.65e-1)" "unprognostic (6.57e-2)" "unprognostic (3.47e-2)" "unprognostic (1.69e-1)" "unprognostic (6.51e-2)" "unprognostic (1.43e-1)" FUT2 "SE, Se2, SEC2, sej" ENSG00000176920 "Fucosyltransferase 2" Q10981 19 48695971-48705951 "Blood group antigen proteins, Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" "Blood group antigen, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 41.8;salivary gland: 58.0;stomach 1: 27.2" "Cell type enhanced" "Detected in many" "Colonocytes: 94.2;Conjunctival goblet cells: 307.8;Enterocytes: 213.1;Esophageal apical cells: 191.6;Esophageal suprabasal cells: 87.8;Foveolar cells: 110.1;Paneth cells: 89.0;Respiratory secretory cells: 121.9;Salivary acinar cells: 94.9;Salivary basal cells: 119.7;Salivary duct cells: 257.1;Salivary ionocytes: 171.5;Submucosal glandular cells: 115.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 20.9;Gastric cancer: 18.6" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Urothelial cells" "Region enhanced" "Detected in some" "cerebellum: 2.3" "Low region specificity" "Detected in all" HPA014402 Uncertain Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 15: Non-specific - Transcription" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 3 "Plasma membrane" Cytosol "HPA014402: " "unprognostic (1.30e-1)" "unprognostic (7.05e-2)" "unprognostic (3.46e-2)" "unprognostic (3.45e-2)" "unprognostic (8.82e-3)" "unprognostic (1.56e-2)" "potential prognostic favorable (4.34e-4)" "unprognostic (2.72e-1)" "unprognostic (1.91e-2)" "unprognostic (3.07e-2)" "potential prognostic unfavorable (1.46e-4)" "unprognostic (4.64e-2)" "unprognostic (2.05e-1)" "unprognostic (2.20e-1)" "unprognostic (4.06e-1)" "unprognostic (2.29e-1)" "unprognostic (1.82e-1)" "unprognostic (3.71e-2)" "unprognostic (5.11e-3)" "unprognostic (3.35e-1)" "unprognostic (5.53e-2)" "unprognostic (1.36e-1)" "unprognostic (7.95e-2)" "potential prognostic favorable (6.43e-4)" "unprognostic (1.97e-1)" "unprognostic (1.37e-1)" "unprognostic (4.03e-2)" FUT3 "CD174, LE" ENSG00000171124 "Fucosyltransferase 3 (Lewis blood group)" P21217 19 5842888-5851471 "Blood group antigen proteins, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Blood group antigen, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 150.8;intestine: 67.6;retina: 76.2;salivary gland: 79.3" "Cell type enriched" "Detected in many" 7 "Esophageal apical cells: 1028.8" "Cell type enriched" "Detected in single" 5 "ependymal cell: 1.2" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 103.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 42.6" "Breast - Breast glandular cells, Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Alveolar cells type 2, Prostate - Urothelial cells, Stomach - Gastric mucous cells" HPA046966 Supported NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 84: Apical squamous epithelium - Cornification" 7 "HPA046966: " "unprognostic (7.11e-3)" "potential prognostic unfavorable (3.59e-4)" "unprognostic (1.61e-1)" "unprognostic (8.72e-2)" "unprognostic (3.80e-3)" "unprognostic (2.13e-1)" "unprognostic (1.17e-2)" "potential prognostic favorable (9.17e-8)" "unprognostic (7.45e-3)" "unprognostic (1.55e-2)" "unprognostic (5.88e-2)" "unprognostic (2.56e-1)" "unprognostic (1.09e-1)" "unprognostic (2.74e-1)" "unprognostic (1.19e-1)" "unprognostic (2.69e-2)" "unprognostic (1.49e-1)" "unprognostic (9.84e-2)" "unprognostic (2.61e-2)" "unprognostic (9.22e-2)" "unprognostic (1.41e-1)" "unprognostic (2.67e-2)" "unprognostic (1.28e-1)" "unprognostic (7.05e-2)" "unprognostic (5.57e-2)" "unprognostic (6.16e-2)" "unprognostic (4.54e-2)" FUT4 "CD15, ELFT, FCT3A, FUC-TIV" ENSG00000196371 "Fucosyltransferase 4" P22083 11 94543921-94549895 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Inflammatory response" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "bone marrow: 96.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "colorectal cancer: 23.2;Leukemia: 23.9" "Testis - Spermatogonia" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB000014, CAB016129" Enhanced Approved Vesicles NA NA "Cluster 15: Bone marrow - Innate immune response" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 89: Adipocytes - Lipid metabolism" Vesicles "CAB000014: , CAB016129: " "unprognostic (4.72e-1)" "unprognostic (3.91e-2)" "unprognostic (1.42e-2)" "unprognostic (1.76e-2)" "unprognostic (5.92e-2)" "unprognostic (1.30e-2)" "unprognostic (2.37e-2)" "unprognostic (4.09e-2)" "unprognostic (5.02e-2)" "unprognostic (3.65e-2)" "unprognostic (9.27e-3)" "unprognostic (2.67e-1)" "unprognostic (1.76e-1)" "unprognostic (1.85e-2)" "unprognostic (9.78e-2)" "potential prognostic unfavorable (6.20e-6)" "unprognostic (8.26e-2)" "unprognostic (7.79e-2)" "unprognostic (2.40e-1)" "unprognostic (3.17e-1)" "unprognostic (2.37e-1)" "unprognostic (1.37e-2)" "unprognostic (1.35e-1)" "unprognostic (9.55e-2)" "unprognostic (1.28e-3)" "unprognostic (2.74e-1)" "unprognostic (6.75e-2)" "unprognostic (5.68e-2)" "unprognostic (2.98e-1)" "unprognostic (8.81e-2)" "unprognostic (6.55e-3)" FUT5 FUC-TV ENSG00000130383 "Fucosyltransferase 5" Q11128 19 5865826-5870540 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 5 "Oocytes: 4.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA046966 Uncertain NA NA "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "HPA046966: " FUT6 "FCT3A, FLJ40754, FT1A, FucT-VI" ENSG00000156413 "Fucosyltransferase 6" P51993 19 5830408-5839722 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 76.6;kidney: 32.8;salivary gland: 43.9" "Cell type enhanced" "Detected in many" "Colonocytes: 56.7;Enteric transient amplifying cells: 47.1;Enterocytes: 131.0;Esophageal apical cells: 517.5;Esophageal suprabasal cells: 48.8;Goblet cells: 89.4;Paneth cells: 54.1;Proximal tubule cells: 129.1;Respiratory secretory cells: 52.9" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in single" "basophil: 1.2" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in some" "colorectal cancer: 7.9;Gastric cancer: 4.4" "Breast - Breast glandular cells (progenitors), Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Alveolar cells type 2, Prostate - Urothelial cells" "HPA043707, HPA046966" Approved Supported "Golgi apparatus" "Secreted to blood" Enzyme NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 48: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" "Golgi apparatus" "HPA043707: , HPA046966: " "unprognostic (5.67e-2)" "unprognostic (4.86e-2)" "unprognostic (2.88e-1)" "unprognostic (2.80e-2)" "unprognostic (7.24e-3)" "unprognostic (4.62e-2)" "potential prognostic favorable (3.21e-4)" "validated prognostic favorable (3.62e-9)" "validated prognostic favorable (2.18e-4)" "potential prognostic favorable (1.08e-5)" "unprognostic (1.33e-1)" "unprognostic (2.22e-1)" "unprognostic (3.43e-2)" "unprognostic (1.14e-1)" "unprognostic (4.01e-2)" "unprognostic (1.04e-1)" "unprognostic (1.29e-2)" "unprognostic (6.84e-3)" "unprognostic (3.02e-1)" "unprognostic (1.49e-2)" "unprognostic (4.28e-2)" FUT7 ENSG00000180549 "Fucosyltransferase 7" Q11130 9 137030174-137032088 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 3.7;lymphoid tissue: 9.2" "Group enriched" "Detected in some" 6 "Neutrophils: 67.6;pDCs: 90.9" "Cell type enriched" "Detected in single" 14 "leukocyte: 2.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 210.4" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 28 "Leukemia: 14.3;lymphoma: 9.2" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Lung - Neutrophils_2, Spleen - Neutrophils_2" "Not detected" "Not detected" "Not detected" "Not detected" HPA042780 Supported "Golgi apparatus" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 11: White matter - Signal transduction" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 2 "Golgi apparatus" "HPA042780: " "unprognostic (1.16e-2)" "unprognostic (2.48e-3)" "potential prognostic favorable (1.57e-5)" "unprognostic (1.87e-3)" "unprognostic (1.13e-2)" FUT8 ENSG00000033170 "Fucosyltransferase 8" Q9BYC5 14 65410592-65744121 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Foveolar cells: 545.4;Mucous neck cells: 704.7;Oligodendrocytes: 1154.6;Plasma cells: 632.2;Salivary acinar cells: 915.7" "Cell type enhanced" "Detected in all" "oligodendrocyte: 1591.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 15.6;NK-cells: 14.8;T-cells: 10.0" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017129, HPA043410" Enhanced Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 35000 "Cluster 24: Non-specific - Transcription" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 72: Neuronal - Signal transduction" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 37 "Golgi apparatus" "Nucleoplasm, Cytosol" "CAB017129: , HPA043410: " "unprognostic (1.23e-1)" "unprognostic (2.13e-1)" "unprognostic (3.44e-2)" "unprognostic (9.97e-2)" "unprognostic (5.76e-2)" "unprognostic (2.41e-1)" "unprognostic (3.25e-1)" "potential prognostic unfavorable (3.36e-4)" "unprognostic (2.26e-2)" "potential prognostic unfavorable (1.05e-4)" "unprognostic (1.74e-2)" "unprognostic (3.04e-2)" "unprognostic (4.15e-2)" "unprognostic (4.24e-2)" "unprognostic (5.50e-2)" "unprognostic (1.52e-2)" "unprognostic (6.23e-2)" "unprognostic (3.16e-2)" "unprognostic (2.39e-1)" "unprognostic (1.17e-2)" "unprognostic (1.48e-1)" "unprognostic (4.32e-2)" "unprognostic (2.12e-1)" "unprognostic (7.24e-2)" "unprognostic (1.06e-2)" "unprognostic (2.64e-1)" "unprognostic (4.66e-2)" "unprognostic (1.05e-1)" "unprognostic (1.98e-1)" "unprognostic (1.39e-1)" "unprognostic (2.16e-1)" FUT9 Fuc-TIX ENSG00000172461 "Fucosyltransferase 9" Q9Y231 6 96015974-96215612 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Carbohydrate metabolism, Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 16.0;stomach 1: 21.8" "Cell type enhanced" "Detected in many" "Astrocytes: 1171.8;Bergmann glia: 649.1;Brain excitatory neurons: 391.1;Brain inhibitory neurons: 426.3;Corticotrophs: 244.4;Ependymal cells: 565.8;Gastric chief cells: 597.4;Mucous neck cells: 1469.9;Oligodendrocyte progenitor cells: 246.8;Oligodendrocytes: 350.9;Parietal cells: 275.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 2.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "thyroid cancer: 2.8" "Adrenal gland - Adrenal medulla cells, Minor Salivary Gland - Minor salivary glandular cells, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070923 Approved "Nucleoplasm,Microtubules,Cytokinetic bridge,Cytosol" Yes No "Cluster 27: Cerebellum - Synaptic function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 28: Astrocytes - Homeostasis & neuron support" 4 Nucleoplasm "Microtubules, Cytokinetic bridge, Cytosol" "HPA070923: " "unprognostic (3.52e-1)" "unprognostic (1.30e-1)" "potential prognostic favorable (6.92e-5)" "unprognostic (8.02e-2)" "unprognostic (4.82e-2)" FUZ "CPLANE3, FLJ22688, Fy" ENSG00000010361 "Fuzzy planar cell polarity protein" Q9BT04 19 49806866-49817376 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation, Protein transport, Transport" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 76.2" "Group enriched" "Detected in many" 4 "Early spermatids: 1418.6;Late spermatids: 3322.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Lung - Respiratory ciliated cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041779, HPA042196" Approved Approved Cytosol No NA "Cluster 29: Non-specific - Unknown function" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 8 Cytosol "HPA041779: , HPA042196: " "unprognostic (9.79e-2)" "unprognostic (3.58e-3)" "unprognostic (1.59e-1)" "unprognostic (4.81e-2)" "unprognostic (2.28e-1)" "unprognostic (4.42e-2)" "unprognostic (3.72e-2)" "unprognostic (2.91e-1)" "unprognostic (1.22e-2)" "unprognostic (2.85e-1)" "unprognostic (3.43e-3)" "unprognostic (5.58e-2)" "potential prognostic favorable (2.22e-5)" "unprognostic (2.23e-2)" "unprognostic (1.16e-2)" "unprognostic (4.73e-2)" "unprognostic (1.36e-1)" "unprognostic (2.63e-3)" "unprognostic (2.41e-1)" "unprognostic (1.97e-1)" "unprognostic (6.62e-2)" "unprognostic (5.01e-2)" "unprognostic (8.19e-2)" "unprognostic (1.48e-1)" "unprognostic (1.69e-2)" "unprognostic (3.21e-2)" "unprognostic (2.98e-2)" "unprognostic (3.58e-3)" "unprognostic (2.95e-1)" "unprognostic (1.11e-1)" "unprognostic (2.06e-1)" FXN "CyaY, FA, FARR, FRDA, X25" ENSG00000165060 Frataxin Q16595 9 69035751-69079076 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Heme biosynthesis, Ion transport, Iron storage, Iron transport, Transport" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 7.9;Hepatocytes: 10.2;Megakaryocyte progenitors: 4.7;Megakaryocytes: 6.2;Oocytes: 13.8;Parietal cells: 10.6;Plasma cells: 4.7" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022164, HPA068304" Supported Supported Mitochondria,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 76: Non-specific - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 67: Plasma cells - Plasma cell differentiation" 10 Mitochondria Cytosol "CAB022164: , HPA068304: " "unprognostic (2.37e-2)" "unprognostic (9.61e-2)" "unprognostic (2.19e-1)" "unprognostic (1.29e-1)" "unprognostic (1.20e-1)" "unprognostic (2.03e-1)" "unprognostic (2.93e-2)" "unprognostic (7.55e-2)" "unprognostic (2.97e-2)" "unprognostic (3.82e-1)" "unprognostic (1.12e-2)" "unprognostic (3.13e-2)" "unprognostic (3.84e-1)" "unprognostic (1.70e-1)" "unprognostic (2.03e-1)" "unprognostic (2.39e-2)" "unprognostic (3.00e-1)" "unprognostic (1.80e-1)" "unprognostic (1.51e-2)" "unprognostic (2.21e-2)" "unprognostic (1.13e-2)" "unprognostic (6.02e-2)" "unprognostic (6.13e-2)" "unprognostic (2.50e-1)" "unprognostic (2.08e-1)" "unprognostic (1.74e-1)" "unprognostic (8.36e-2)" "unprognostic (1.65e-1)" "unprognostic (2.15e-1)" "unprognostic (1.52e-1)" "unprognostic (5.23e-2)" FXR1 ENSG00000114416 "FMR1 autosomal homolog 1" P51114 3 180868141-180982753 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Myogenesis, Spermatogenesis" "Developmental protein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "skeletal muscle: 741.3;tongue: 425.1" "Cell type enhanced" "Detected in all" "Early spermatids: 1104.9;Late primary spermatocytes: 869.8;Late spermatids: 2893.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018246, HPA055475" Approved Enhanced Cytosol NA NA 16000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 75: Non-specific - Chaperones and protein folding" 131 Cytosol "HPA018246: , HPA055475: " "unprognostic (1.17e-1)" "unprognostic (1.05e-1)" "unprognostic (2.37e-2)" "unprognostic (1.91e-1)" "unprognostic (4.65e-2)" "potential prognostic unfavorable (8.29e-4)" "unprognostic (4.51e-2)" "unprognostic (7.32e-3)" "unprognostic (1.04e-3)" "unprognostic (3.21e-2)" "unprognostic (3.85e-3)" "unprognostic (1.71e-1)" "potential prognostic unfavorable (3.75e-4)" "validated prognostic unfavorable (3.39e-6)" "validated prognostic unfavorable (3.53e-4)" "validated prognostic unfavorable (6.58e-5)" "validated prognostic unfavorable (2.68e-4)" "unprognostic (3.43e-2)" "unprognostic (3.28e-2)" "unprognostic (1.73e-2)" "unprognostic (4.02e-3)" "unprognostic (1.32e-3)" "potential prognostic unfavorable (3.84e-4)" "potential prognostic unfavorable (3.49e-4)" "unprognostic (6.77e-2)" "unprognostic (2.57e-1)" "unprognostic (7.60e-2)" "unprognostic (3.04e-2)" "unprognostic (6.04e-2)" "unprognostic (2.52e-1)" "unprognostic (1.37e-1)" FXR2 FMR1L2 ENSG00000129245 "FMR1 autosomal homolog 2" P51116 17 7591230-7614897 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 113.4" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011205, HPA022997" Supported Supported Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 142 Cytosol "CAB011205: , HPA022997: " "unprognostic (4.28e-1)" "unprognostic (4.22e-2)" "unprognostic (4.20e-1)" "unprognostic (2.47e-1)" "unprognostic (2.67e-1)" "unprognostic (2.08e-2)" "unprognostic (1.11e-1)" "potential prognostic favorable (3.61e-4)" "unprognostic (8.95e-3)" "unprognostic (7.04e-3)" "potential prognostic favorable (5.41e-5)" "unprognostic (1.23e-2)" "unprognostic (4.20e-2)" "unprognostic (4.49e-2)" "unprognostic (2.42e-1)" "unprognostic (1.61e-2)" "unprognostic (5.36e-2)" "unprognostic (4.66e-2)" "unprognostic (7.01e-2)" "unprognostic (2.89e-1)" "unprognostic (2.26e-1)" "potential prognostic favorable (4.70e-4)" "unprognostic (7.85e-3)" "unprognostic (3.45e-1)" "unprognostic (2.76e-1)" "unprognostic (3.38e-2)" "unprognostic (2.08e-1)" "unprognostic (3.58e-1)" "unprognostic (2.62e-1)" "unprognostic (1.13e-1)" "unprognostic (1.50e-1)" FXYD1 PLM ENSG00000266964 "FXYD domain containing ion transport regulator 1" O00168 19 35138824-35143109 "Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 1674.5;skeletal muscle: 1295.2" "Group enriched" "Detected in some" 4 "Astrocytes: 115.8;Bergmann glia: 262.7" "Cell type enhanced" "Detected in many" "astrocyte: 122.7;Bergmann glia: 336.8;choroid plexus epithelial cell: 106.5" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 222.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 11.1" "Group enriched" "Detected in many" 4 "B-cells: 11.1;T-cells: 6.9" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 6.9" "Breast - Fibroblasts, Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Kidney - Fibroblasts, Liver - Hepatocytes, Pituitary gland - Fibroblasts, Prostate - Fibroblasts, Spleen - Fibroblasts_2, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" HPA026873 Approved Nucleoplasm,Nucleoli,Cytosol No NA 54000 "Cluster 16: Non-specific - Cell proliferation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 28: Astrocytes - Homeostasis & neuron support" 1 "Nucleoplasm, Cytosol" Nucleoli "HPA026873: " "unprognostic (1.89e-3)" "unprognostic (1.36e-1)" "potential prognostic favorable (5.20e-4)" "potential prognostic favorable (5.06e-4)" "unprognostic (2.36e-1)" "unprognostic (2.41e-1)" "unprognostic (2.93e-3)" "unprognostic (7.78e-3)" "unprognostic (2.62e-2)" "unprognostic (5.12e-2)" "unprognostic (7.83e-2)" "unprognostic (4.54e-1)" "potential prognostic unfavorable (7.96e-6)" "unprognostic (2.85e-2)" "unprognostic (2.75e-2)" "potential prognostic favorable (5.04e-4)" "unprognostic (7.15e-2)" "unprognostic (3.89e-2)" "unprognostic (2.06e-1)" "unprognostic (2.99e-2)" "unprognostic (1.20e-1)" "unprognostic (3.64e-2)" "unprognostic (1.77e-3)" "unprognostic (1.49e-1)" "unprognostic (4.39e-2)" "unprognostic (3.07e-1)" "unprognostic (2.79e-2)" "unprognostic (6.29e-3)" "unprognostic (2.19e-1)" "unprognostic (3.86e-2)" "unprognostic (3.05e-1)" FXYD2 "ATP1G1, HOMG2, MGC12372" ENSG00000137731 "FXYD domain containing ion transport regulator 2" P54710 11 117800844-117828698 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Disease variant, FDA approved drug targets, Primary hypomagnesemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "kidney: 3774.6" "Group enriched" "Detected in some" 6 "Cholangiocytes: 1856.7;Epididymal efferent duct absorptive cells: 1010.9" "Cell type enhanced" "Detected in single" "committed oligodendrocyte precursor: 1.1" "Group enriched" "Detected in many" 10 "Kidney Chromophobe (TCGA): 5066.0;Kidney Renal Clear Cell Carcinoma (TCGA): 1982.2;Kidney Renal Papillary Cell Carcinoma (TCGA): 2051.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "memory CD8 T-cell: 14.8;naive CD4 T-cell: 5.1;naive CD8 T-cell: 4.4;NK-cell: 9.6;plasmacytoid DC: 3.8" "Group enriched" "Detected in many" 7 "dendritic cells: 3.8;NK-cells: 9.6;T-cells: 14.8" "Cancer enhanced" "Detected in many" "Kidney cancer: 220.9;Uterine cancer: 89.5" "Liver - Cholangiocytes, Minor Salivary Gland - Minor salivary gland ductal cells, Prostate - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in many" "Region enriched" "Detected in some" 5 "spinal cord: 30.5" "HPA064218, HPA068838" Supported Approved Mitochondria NA NA 140000 "Cluster 24: Non-specific - Transcription" "Cluster 72: Kidney - Transmembrane transport" "Cluster 53: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 1 Mitochondria "HPA064218: , HPA068838: " "unprognostic (2.74e-1)" "unprognostic (7.26e-3)" "unprognostic (1.03e-2)" "potential prognostic favorable (9.17e-4)" "unprognostic (5.31e-2)" "unprognostic (6.59e-2)" "unprognostic (7.78e-2)" "unprognostic (1.67e-3)" "unprognostic (5.18e-2)" "unprognostic (1.45e-2)" "potential prognostic favorable (1.05e-6)" "unprognostic (1.30e-3)" "potential prognostic favorable (8.22e-6)" "unprognostic (1.06e-3)" "unprognostic (3.04e-2)" "unprognostic (4.99e-3)" "unprognostic (9.11e-2)" "unprognostic (1.17e-1)" "unprognostic (9.82e-2)" "unprognostic (9.50e-2)" "unprognostic (1.25e-2)" "unprognostic (5.90e-3)" "unprognostic (2.01e-2)" "unprognostic (1.73e-1)" "unprognostic (1.34e-2)" "unprognostic (1.60e-1)" "unprognostic (4.09e-2)" "unprognostic (2.07e-1)" "unprognostic (5.20e-2)" FXYD3 "MAT-8, PLML" ENSG00000089356 "FXYD domain containing ion transport regulator 3" Q14802 19 35115823-35124324 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1697.0" "Cell type enhanced" "Detected in many" "Colonocytes: 108.3;Enteric transient amplifying cells: 18.8;Enterocytes: 31.0;Foveolar cells: 18.3;Gastric chief cells: 16.4;Goblet cells: 26.9;Papillary tip epithelial cells: 80.6;Renal collecting duct principal cells: 15.3" "Cell type enhanced" "Detected in some" "astrocyte: 4.5;choroid plexus epithelial cell: 14.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 1961.9" "Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 1, Pituitary gland - Somatotropes, Stomach - Gastric mucous cells" "Low region specificity" "Detected in some" "Region enhanced" "Detected in some" "spinal cord: 5.1" HPA010856 Supported Approved "Nucleoplasm,Plasma membrane" "Intracellular and membrane" Transport NA NA "Cluster 77: Intestine - Digestion" "Cluster 39: Astrocytes - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 1 Nucleoplasm "Plasma membrane" "HPA010856: " "unprognostic (1.33e-2)" "unprognostic (3.46e-2)" "unprognostic (6.96e-2)" "unprognostic (5.10e-2)" "unprognostic (8.95e-3)" "unprognostic (2.21e-2)" "unprognostic (9.04e-2)" "unprognostic (2.19e-1)" "unprognostic (1.55e-1)" "potential prognostic unfavorable (6.32e-8)" "unprognostic (4.97e-2)" "unprognostic (4.57e-1)" "unprognostic (2.11e-3)" "unprognostic (2.92e-3)" "unprognostic (3.87e-2)" "unprognostic (4.73e-3)" "unprognostic (2.72e-1)" "unprognostic (5.24e-2)" "unprognostic (1.91e-1)" "unprognostic (3.61e-2)" "unprognostic (1.09e-2)" "unprognostic (2.32e-2)" "unprognostic (6.70e-2)" "unprognostic (3.52e-2)" "potential prognostic unfavorable (2.53e-4)" "unprognostic (4.26e-1)" "unprognostic (8.82e-2)" "unprognostic (8.34e-2)" "unprognostic (6.11e-2)" "unprognostic (5.82e-2)" FXYD4 CHIF ENSG00000150201 "FXYD domain containing ion transport regulator 4" P59646 10 43371636-43376335 "Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 46 "kidney: 300.9" "Group enriched" "Detected in some" 7 "Papillary tip epithelial cells: 131.1;Parietal cells: 134.4;Renal collecting duct principal cells: 521.2" "Cell type enriched" "Detected in single" 6 "oligodendrocyte: 3.9" "Group enriched" "Detected in many" 9 "Bladder Urothelial Carcinoma (TCGA): 53.2;Kidney Chromophobe (TCGA): 91.7;Kidney Renal Papillary Cell Carcinoma (TCGA): 30.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "lung cancer: 3.0;testis cancer: 9.5" "Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA058421 Enhanced Uncertain Cytosol NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 11: White matter - Signal transduction" "Cluster 7: Liver cancer - Metabolism" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" Cytosol "HPA058421: " "unprognostic (5.01e-2)" "unprognostic (1.05e-2)" "unprognostic (1.04e-1)" "unprognostic (2.83e-1)" "unprognostic (2.37e-1)" "unprognostic (4.41e-2)" "unprognostic (3.85e-1)" "unprognostic (3.31e-1)" "potential prognostic favorable (8.05e-4)" "unprognostic (1.52e-1)" "unprognostic (7.17e-3)" "unprognostic (1.11e-2)" "unprognostic (2.48e-1)" "unprognostic (8.49e-2)" FXYD5 OIT2 ENSG00000089327 "FXYD domain containing ion transport regulator 5" Q96DB9 19 35154730-35169881 "Plasma proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "cDC: 306.4;Decidual stromal cells: 269.7;Esophageal apical cells: 1086.9;Extravillous trophoblasts: 668.2;Hofbauer cells: 341.8;Innate lymphoid cells: 529.2;Mast cells: 450.8;Megakaryocytes: 259.6;monocytes: 302.9;Platelets: 470.4;T-cells: 282.9" "Group enriched" "Detected in many" 4 "central nervous system macrophage: 46.5;endothelial cell: 83.9;leukocyte: 105.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells, Liver - Vascular endothelial cells, Prostate - Fibroblasts, Testis - Endothelial cells" HPA010817 Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 69: Skin cancer - ECM organization" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" "Endoplasmic reticulum" "HPA010817: " "potential prognostic favorable (4.84e-4)" "unprognostic (2.27e-2)" "unprognostic (1.76e-1)" "unprognostic (4.13e-3)" "unprognostic (2.38e-2)" "unprognostic (3.93e-1)" "unprognostic (5.00e-3)" "unprognostic (5.42e-3)" "unprognostic (2.10e-3)" "unprognostic (3.22e-1)" "unprognostic (1.34e-3)" "unprognostic (6.76e-2)" "unprognostic (1.07e-1)" "unprognostic (1.41e-1)" "unprognostic (1.12e-1)" "potential prognostic unfavorable (2.13e-4)" "unprognostic (5.83e-2)" "unprognostic (1.35e-2)" "unprognostic (1.12e-1)" "potential prognostic unfavorable (3.21e-4)" "unprognostic (8.82e-2)" "unprognostic (6.29e-2)" "unprognostic (3.00e-1)" "unprognostic (5.45e-2)" "unprognostic (6.58e-2)" "unprognostic (1.17e-1)" "unprognostic (4.65e-1)" "unprognostic (8.60e-2)" "unprognostic (6.34e-2)" "unprognostic (7.50e-2)" "unprognostic (1.35e-1)" FXYD6 ENSG00000137726 "FXYD domain containing ion transport regulator 6" Q9H0Q3 11 117836976-117877486 "Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Brain inhibitory neurons: 2.6;Breast myoepithelial cells: 2.6;Granulosa cells: 3.2;Hepatic stellate cells: 12.9;Leydig cells: 2.4;Lymphatic endothelial cells: 6.3;Oligodendrocyte progenitor cells: 2.3;Other brain neurons: 3.8;Pericytes: 4.2;Peritubular myoid cells: 5.7;Sertoli cells: 3.2;Smooth muscle cells: 4.8" "Cell type enhanced" "Detected in many" "CGE interneuron: 10.2;LAMP5-LHX6 and Chandelier: 8.7" "Cancer enriched" "Detected in all" 4 "Glioblastoma Multiforme (TCGA): 639.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "classical monocyte: 37.7" "Lineage enriched" "Detected in many" 6 "monocytes: 37.7" "Cancer enhanced" "Detected in many" "Neuroblastoma: 151.9" "Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Spleen - Endothelial cells, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041334, HPA042284" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 65: Brain - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 110: Mural cells - ECM organization" 44 "Nucleoplasm, Cytosol" "HPA041334: , HPA042284: " "unprognostic (4.71e-2)" "unprognostic (1.64e-2)" "unprognostic (1.41e-2)" "unprognostic (5.15e-2)" "unprognostic (1.95e-2)" "unprognostic (7.90e-2)" "unprognostic (2.71e-2)" "potential prognostic favorable (7.57e-4)" "unprognostic (1.39e-1)" "unprognostic (9.99e-2)" "potential prognostic favorable (2.39e-5)" "unprognostic (5.37e-3)" "unprognostic (2.78e-3)" "unprognostic (2.24e-3)" "potential prognostic favorable (5.85e-5)" "unprognostic (9.83e-2)" "unprognostic (1.34e-1)" "unprognostic (5.50e-2)" "unprognostic (9.49e-2)" "unprognostic (1.75e-1)" "unprognostic (8.71e-2)" "unprognostic (1.42e-3)" "unprognostic (8.79e-2)" "unprognostic (3.49e-2)" "unprognostic (1.35e-2)" "unprognostic (2.46e-2)" "unprognostic (2.58e-2)" "unprognostic (5.05e-3)" "unprognostic (2.60e-1)" "unprognostic (1.57e-1)" "unprognostic (2.85e-2)" FXYD6-FXYD2 ENSG00000255245 "FXYD6-FXYD2 readthrough" 11 117820163-117876667 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "kidney: 6.8;salivary gland: 4.2" "Group enriched" "Detected in some" 6 "Distal convoluted tubule cells: 25.7;Loop of henle epithelial cells: 26.2" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 4.0" "Group enriched" "Detected in some" 5 "Kidney Chromophobe (TCGA): 11.6;Kidney Renal Clear Cell Carcinoma (TCGA): 5.3;Kidney Renal Papillary Cell Carcinoma (TCGA): 6.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA068838, HPA075209" Approved Approved "Nuclear membrane,Vesicles" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 15: Kidney cancer - Membrane components" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" "Nuclear membrane, Vesicles" "HPA068838: , HPA075209: " "unprognostic (4.42e-2)" "unprognostic (1.51e-1)" "validated prognostic favorable (3.49e-5)" "validated prognostic favorable (2.02e-4)" "unprognostic (1.45e-2)" "unprognostic (2.71e-3)" FXYD7 ENSG00000221946 "FXYD domain containing ion transport regulator 7" P58549 19 35143250-35154302 "Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 44 "brain: 322.5" "Cell type enhanced" "Detected in some" "Astrocytes: 10.5;Bergmann glia: 19.7;Brain excitatory neurons: 41.1;Brain inhibitory neurons: 25.4;Innate lymphoid cells: 58.8;Other brain neurons: 33.3;T-cells: 16.2" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Glioblastoma Multiforme (TCGA): 25.6;Ovary Serous Cystadenocarcinoma (TCGA): 15.4;Skin Cutaneous Melanoma (TCGA): 6.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 52.3" "Group enriched" "Detected in many" 23 "B-cells: 19.1;NK-cells: 52.3;T-cells: 23.8" "Cancer enhanced" "Detected in some" "Adrenocortical cancer: 5.3;skin cancer: 5.4" "Adipose visceral - Mesothelial cells, Colon - Enteric glia cells, Spleen - B-cells (Spleen), Thyroid gland - T-cells" "Low region specificity" "Detected in all" HPA026916 Approved NA NA "Cluster 24: Non-specific - Transcription" "Cluster 78: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 98: Neurons - Neurotransmission & signaling" 2 "HPA026916: " "unprognostic (1.74e-3)" "unprognostic (3.92e-2)" "unprognostic (7.06e-2)" "unprognostic (2.29e-2)" "unprognostic (2.34e-1)" "unprognostic (5.34e-2)" "unprognostic (3.23e-1)" "unprognostic (1.55e-1)" "unprognostic (3.50e-1)" FYB1 "ADAP, FYB, FYB-120/130, SLAP-130" ENSG00000082074 "FYN binding protein 1" O15117 5 39105252-39274528 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 50.1;lymphoid tissue: 105.1" "Cell type enhanced" "Detected in many" "Kupffer cells: 865.0;Macrophages: 459.2;Megakaryocyte progenitors: 387.6;Megakaryocytes: 636.7;Microglia: 985.5;monocytes: 698.2;Neutrophil progenitors: 1172.2;Neutrophils: 2831.2;Platelets: 899.6;T-cells: 587.4;Tuft cells: 1798.4" "Group enriched" "Detected in many" 36 "central nervous system macrophage: 1253.7;leukocyte: 822.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1680.2" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "head and neck cancer: 20.1;Leukemia: 33.9" "Adrenal gland - Macrophages, Breast - T-cells, Prostate - T-cells, Skin - T-cells, Testis - Early spermatids, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB025336, HPA026796, HPA067427" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 4400000 "Cluster 21: Neutrophils - Unknown function" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 24: Neutrophils - Innate immunity signal integration" 14 "Plasma membrane" Nucleoplasm "CAB025336: , HPA026796: , HPA067427: " "unprognostic (1.76e-1)" "unprognostic (4.36e-2)" "unprognostic (3.74e-2)" "unprognostic (1.80e-1)" "unprognostic (2.51e-1)" "unprognostic (4.27e-1)" "unprognostic (1.15e-1)" "unprognostic (3.31e-2)" "unprognostic (1.54e-1)" "unprognostic (3.78e-2)" "unprognostic (2.71e-1)" "unprognostic (1.15e-2)" "unprognostic (2.81e-1)" "unprognostic (1.88e-2)" "unprognostic (8.82e-2)" "unprognostic (1.86e-1)" "unprognostic (8.74e-2)" "unprognostic (1.63e-1)" "unprognostic (7.63e-2)" "unprognostic (5.82e-2)" "potential prognostic unfavorable (2.11e-4)" "unprognostic (2.98e-1)" "unprognostic (8.25e-3)" "unprognostic (4.07e-2)" "unprognostic (1.17e-1)" "unprognostic (9.85e-2)" "unprognostic (5.52e-2)" "unprognostic (2.77e-1)" "unprognostic (1.62e-1)" FYB2 "ARAP, C1orf168, FLJ43208, RP4-758N20.2" ENSG00000187889 "FYN binding protein 2" Q5VWT5 1 56718789-56819696 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 10.6;fallopian tube: 12.9;liver: 16.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 234.1;Choroid plexus epithelial cells: 943.3;Epididymal clear cells: 381.7;Pituitary stem cells: 284.0;Renal collecting duct intercalated cells: 794.9;Renal collecting duct principal cells: 419.5;Renal connecting tubule cells: 264.6;Respiratory ciliated cells: 372.6;Respiratory ionocytes: 561.4;Respiratory secretory cells: 281.7;Retinal pigment epithelial cells: 567.0" "Cell type enriched" "Detected in many" 33 "choroid plexus epithelial cell: 702.3" "Cancer enhanced" "Detected in some" "Kidney Chromophobe (TCGA): 6.3" "Region enriched" "Detected in some" 13 "choroid plexus: 31.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Breast glandular cells, Colon - Colon enterocytes, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Prostate - Prostate glandular cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Region enhanced" "Detected in single" "hippocampal formation: 2.1" "Low region specificity" "Detected in many" HPA054923 Uncertain "Perinuclear theca,Mid piece,Principal piece" NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" "Perinuclear theca, Mid piece, Principal piece" "HPA054923: " "unprognostic (6.46e-3)" "unprognostic (1.42e-1)" "unprognostic (1.57e-2)" "unprognostic (5.20e-3)" "unprognostic (4.85e-2)" "unprognostic (1.08e-1)" "unprognostic (2.12e-1)" FYCO1 "FLJ13335, ZFYVE7" ENSG00000163820 "FYVE and coiled-coil domain autophagy adaptor 1" Q9BQS8 3 45917903-45995824 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 246.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 97.3;Myonuclei: 226.1;Rod photoreceptor cells: 156.7" "Cell type enhanced" "Detected in many" "leukocyte: 54.0;vascular associated smooth muscle cell: 47.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Lung - Fibroblasts_1, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035526, HPA057966" Uncertain Enhanced Vesicles NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 19: Astrocytes - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 55: Myocytes - Oxidative muscle function" 36 Vesicles "HPA035526: , HPA057966: " "unprognostic (6.65e-3)" "unprognostic (1.29e-1)" "unprognostic (7.65e-2)" "unprognostic (2.16e-1)" "unprognostic (2.25e-1)" "unprognostic (3.02e-1)" "unprognostic (2.68e-2)" "unprognostic (7.08e-2)" "unprognostic (1.96e-2)" "unprognostic (1.96e-2)" "potential prognostic favorable (3.68e-7)" "unprognostic (1.83e-2)" "unprognostic (1.52e-3)" "unprognostic (2.34e-3)" "unprognostic (6.49e-2)" "potential prognostic favorable (1.98e-4)" "unprognostic (2.16e-2)" "unprognostic (1.10e-1)" "unprognostic (1.69e-1)" "unprognostic (9.75e-2)" "unprognostic (1.92e-2)" "unprognostic (1.77e-1)" "unprognostic (1.71e-1)" "unprognostic (1.06e-1)" "unprognostic (4.53e-2)" "unprognostic (1.44e-2)" "unprognostic (8.90e-2)" "unprognostic (9.77e-2)" "unprognostic (2.28e-1)" "unprognostic (2.92e-2)" "unprognostic (1.68e-1)" FYN "MGC45350, SLK, SYN" ENSG00000010810 "FYN proto-oncogene, Src family tyrosine kinase" P06241 6 111660332-111873452 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Host-virus interaction, Immunity" "Developmental protein, Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 707.1;Bergmann glia: 770.9;Innate lymphoid cells: 1307.3;NK-cells: 1966.4;Oligodendrocyte progenitor cells: 609.8;Oligodendrocytes: 813.6;Podocytes: 1092.5;T-cells: 2000.5" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 3021.6" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 182.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 17 "NK-cells: 69.0;T-cells: 174.7" "Low cancer specificity" "Detected in all" "Adrenal gland - Endothelial cells, Breast - Endothelial cells, Lung - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005034, CAB018387, HPA023887, HPA063770" Approved Supported "Plasma membrane,Cytosol" NA NA 290000 "Cluster 1: T-cells - Unknown function" "Cluster 73: Brain - Neuronal signaling" "Cluster 39: Astrocytes - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 141 "Plasma membrane" Cytosol "CAB005034: , CAB018387: , HPA023887: , HPA063770: " "unprognostic (3.58e-1)" "unprognostic (1.91e-2)" "unprognostic (9.86e-2)" "unprognostic (5.15e-2)" "unprognostic (1.91e-1)" "unprognostic (3.16e-2)" "unprognostic (1.09e-1)" "unprognostic (2.68e-2)" "unprognostic (2.72e-2)" "unprognostic (8.15e-2)" "validated prognostic favorable (1.08e-5)" "validated prognostic favorable (3.70e-5)" "unprognostic (8.27e-3)" "validated prognostic favorable (7.38e-4)" "validated prognostic favorable (5.08e-5)" "unprognostic (8.88e-3)" "unprognostic (1.04e-1)" "unprognostic (8.18e-3)" "unprognostic (7.02e-2)" "unprognostic (1.45e-2)" "unprognostic (6.71e-2)" "unprognostic (3.54e-3)" "unprognostic (1.36e-2)" "unprognostic (3.55e-1)" "unprognostic (4.15e-2)" "unprognostic (2.37e-1)" "unprognostic (4.90e-2)" "unprognostic (3.47e-2)" "unprognostic (6.87e-2)" "unprognostic (1.48e-2)" "unprognostic (1.92e-1)" FYTTD1 "DKFZp761B1514, UIF" ENSG00000122068 "Forty-two-three domain containing 1" Q96QD9 3 197737179-197787596 "Predicted intracellular proteins" "mRNA transport, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 214.3;Esophageal apical cells: 243.6;pDCs: 246.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054474, HPA074880" Enhanced Supported "Nucleoplasm,Nucleoli,Nuclear speckles,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 20 "Nucleoplasm, Nuclear speckles" "Nucleoli, Cytosol" "HPA054474: , HPA074880: " "unprognostic (1.26e-1)" "unprognostic (5.32e-2)" "unprognostic (6.05e-2)" "unprognostic (7.29e-2)" "unprognostic (1.44e-1)" "unprognostic (6.46e-3)" "unprognostic (2.46e-1)" "unprognostic (5.46e-2)" "unprognostic (1.16e-1)" "unprognostic (1.09e-2)" "potential prognostic favorable (2.92e-5)" "unprognostic (2.93e-3)" "unprognostic (2.76e-1)" "unprognostic (9.34e-2)" "unprognostic (8.34e-2)" "unprognostic (1.10e-2)" "unprognostic (1.81e-2)" "unprognostic (2.89e-1)" "unprognostic (9.92e-2)" "unprognostic (5.40e-2)" "unprognostic (1.01e-2)" "unprognostic (7.51e-3)" "unprognostic (2.76e-3)" "unprognostic (7.82e-2)" "unprognostic (8.93e-2)" "unprognostic (2.46e-2)" "unprognostic (6.15e-2)" "unprognostic (9.12e-2)" "unprognostic (1.41e-1)" "unprognostic (2.47e-1)" "unprognostic (8.25e-2)" FZD1 DKFZp564G072 ENSG00000157240 "Frizzled class receptor 1" Q9UP38 7 91264433-91271326 "Cancer-related genes, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Transporters" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 46.3;Breast secretory cells: 31.9;Cholangiocytes: 52.4;Peritubular myoid cells: 50.3;Pituicytes/FSCs: 36.4;Retinal horizontal cells: 96.2" "Cell type enhanced" "Detected in many" "midbrain-derived inhibitory: 27.6;pericyte: 27.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 2.0;non-classical monocyte: 2.8" "Lineage enriched" "Detected in single" 5 "monocytes: 2.8" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblasts_1, Skin - Eccrine sweat gland cells, Spleen - Fibroblasts_1, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB013008 Approved Supported "Plasma membrane" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 44: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" "Plasma membrane" "CAB013008: " "unprognostic (2.07e-2)" "unprognostic (1.98e-1)" "unprognostic (4.30e-2)" "unprognostic (1.14e-1)" "unprognostic (1.01e-1)" "unprognostic (6.80e-3)" "unprognostic (7.21e-3)" "potential prognostic unfavorable (1.57e-4)" "unprognostic (3.04e-1)" "unprognostic (2.26e-2)" "potential prognostic favorable (5.19e-12)" "unprognostic (7.92e-3)" "unprognostic (5.22e-3)" "unprognostic (1.48e-2)" "unprognostic (3.37e-1)" "unprognostic (6.45e-3)" "unprognostic (2.27e-2)" "unprognostic (6.32e-2)" "unprognostic (1.13e-1)" "unprognostic (4.23e-3)" "unprognostic (1.49e-3)" "unprognostic (1.98e-1)" "unprognostic (2.20e-1)" "unprognostic (5.13e-3)" "unprognostic (3.08e-2)" "unprognostic (6.34e-2)" "unprognostic (7.20e-3)" "unprognostic (1.18e-2)" "unprognostic (4.17e-2)" "unprognostic (2.44e-1)" "unprognostic (2.66e-2)" FZD10 CD350 ENSG00000111432 "Frizzled class receptor 10" Q9ULW2 12 130162459-130165740 "CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 15.7;skin 1: 8.9" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 6.7;Basal prostatic cells: 6.6;Esophageal apical cells: 65.9;Esophageal basal cells: 12.5;Esophageal suprabasal cells: 23.5;Fibroblasts: 14.5;Lymphatic endothelial cells: 20.5;Myosatellite cells: 10.8;Pericytes: 10.8;Suprabasal keratinocytes: 11.4;Vascular smooth muscle cells: 7.8" "Group enriched" "Detected in some" 4 "fibroblast: 10.2;pericyte: 23.2;vascular associated smooth muscle cell: 11.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 3.3;Esophageal cancer: 3.1" "Adipose subcutaneous - Smooth muscle cells, Skeletal muscle - Fibroblasts, Testis - Spermatogonia" "Region enhanced" "Detected in many" "thalamus: 7.0" "Low region specificity" "Detected in many" "HPA014484, HPA014485" Uncertain Approved Nucleoplasm NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 19: Astrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 17: Non-specific - RNA processing" 6 Nucleoplasm "HPA014484: , HPA014485: " "unprognostic (2.61e-1)" "unprognostic (1.15e-1)" "unprognostic (2.25e-3)" "unprognostic (1.42e-1)" "unprognostic (3.34e-2)" "unprognostic (5.60e-2)" "unprognostic (4.85e-2)" "unprognostic (1.50e-1)" "unprognostic (9.55e-3)" "unprognostic (6.71e-2)" "unprognostic (1.39e-2)" "unprognostic (3.74e-2)" "unprognostic (7.92e-2)" "unprognostic (8.70e-3)" "unprognostic (1.21e-1)" "unprognostic (3.96e-2)" "unprognostic (1.89e-1)" "unprognostic (3.94e-1)" "unprognostic (1.46e-2)" FZD2 ENSG00000180340 "Frizzled class receptor 2" Q14332 17 44557484-44561262 "Cancer-related genes, Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 9.4;choroid plexus: 8.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 28.9;cDC: 11.6;Choroid plexus epithelial cells: 12.8;Fibroblasts: 11.7;Hepatic stellate cells: 12.9;Leydig cells: 45.3;Microglia: 14.1;Monocyte progenitors: 13.1;monocytes: 11.2;Peritubular myoid cells: 35.1;Podocytes: 17.0;Retinal pigment epithelial cells: 12.8" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 16.0;choroid plexus epithelial cell: 14.4;fibroblast: 24.3" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 6 "choroid plexus: 21.1" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.1;myeloid DC: 1.8" "Group enriched" "Detected in many" 7 "dendritic cells: 1.8;monocytes: 1.1" "Low cancer specificity" "Detected in all" "Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA057667 Uncertain Uncertain "Nucleoplasm,Nuclear bodies,Cell Junctions,Actin filaments,Basal body" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 94: Gonadal somatic cells - Mixed function" 1 "Nucleoplasm, Nuclear bodies, Cell Junctions" "Actin filaments, Basal body" "HPA057667: " "unprognostic (4.96e-2)" "unprognostic (3.28e-2)" "unprognostic (4.14e-1)" "unprognostic (3.76e-2)" "unprognostic (3.51e-2)" "unprognostic (3.07e-1)" "unprognostic (6.49e-2)" "unprognostic (1.20e-3)" "unprognostic (8.27e-3)" "unprognostic (3.20e-1)" "validated prognostic unfavorable (6.80e-5)" "validated prognostic unfavorable (9.98e-4)" "unprognostic (1.09e-1)" "unprognostic (1.36e-1)" "unprognostic (9.37e-2)" "unprognostic (1.82e-1)" "unprognostic (7.84e-3)" "unprognostic (9.78e-2)" "unprognostic (3.92e-1)" "unprognostic (6.39e-3)" "unprognostic (7.95e-2)" "unprognostic (1.56e-1)" "unprognostic (3.68e-1)" "unprognostic (4.58e-2)" "unprognostic (1.00e-1)" "unprognostic (5.16e-3)" "unprognostic (5.35e-2)" "unprognostic (7.95e-3)" "unprognostic (2.66e-2)" FZD3 ENSG00000104290 "Frizzled class receptor 3" Q9NPG1 8 28494205-28574267 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Neurogenesis, Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 13.6" "Cell type enhanced" "Detected in many" "Bergmann glia: 223.5;Brain inhibitory neurons: 146.4;Choroid plexus epithelial cells: 235.8;Cone photoreceptor cells: 132.5;Ependymal cells: 380.9;Pituitary stem cells: 171.2;Rod photoreceptor cells: 154.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 9.3" "Group enriched" "Detected in many" 5 "dendritic cells: 9.3;T-cells: 2.3" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Minor Salivary Gland - Minor salivary glandular cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB024995, HPA042320" Approved Approved "Nucleoplasm,Nuclear membrane,Vesicles" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 40: Non-specific - Unknown function" "Cluster 34: Ciliated cells - Cilia assembly & function" Nucleoplasm "Nuclear membrane, Vesicles" "CAB024995: , HPA042320: " "unprognostic (2.29e-1)" "unprognostic (2.42e-2)" "unprognostic (4.26e-2)" "unprognostic (5.33e-2)" "potential prognostic favorable (7.68e-5)" "unprognostic (3.16e-2)" "unprognostic (2.87e-1)" "unprognostic (4.39e-1)" "potential prognostic unfavorable (5.39e-4)" "unprognostic (2.99e-2)" "unprognostic (1.16e-2)" "unprognostic (2.26e-2)" "unprognostic (3.68e-2)" "unprognostic (3.80e-2)" "unprognostic (2.13e-1)" "unprognostic (2.67e-1)" "unprognostic (6.15e-2)" "unprognostic (1.02e-2)" "unprognostic (1.17e-1)" "unprognostic (6.18e-2)" "unprognostic (9.96e-2)" "unprognostic (1.96e-2)" "unprognostic (3.56e-3)" "potential prognostic favorable (5.23e-4)" "unprognostic (1.09e-1)" "unprognostic (1.05e-1)" "unprognostic (1.44e-1)" "unprognostic (3.95e-2)" "unprognostic (1.22e-1)" FZD4 "CD344, EVR1" ENSG00000174804 "Frizzled class receptor 4" Q9ULV1 11 86945679-86955395 "CD markers, Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 112.7" "Cell type enhanced" "Detected in many" "Adipocytes: 189.5;Distal convoluted tubule cells: 78.1;Fibro-adipogenic progenitors: 53.6;Lymphatic endothelial cells: 43.1;Pituitary stem cells: 58.0;Renal connecting tubule cells: 65.7;Thymic myoid cells: 58.5;Vascular endothelial cells: 92.4" "Cell type enriched" "Detected in many" 4 "endothelial cell: 83.6" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 42.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Prostate - Endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042328, HPA074833" Approved Supported "Nucleoplasm,Plasma membrane,Primary cilium" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 89: Adipocytes - Lipid metabolism" 7 "Plasma membrane" "Nucleoplasm, Primary cilium" "HPA042328: , HPA074833: " "unprognostic (5.42e-2)" "unprognostic (1.25e-1)" "unprognostic (6.24e-3)" "unprognostic (7.78e-3)" "unprognostic (2.34e-1)" "unprognostic (1.51e-2)" "unprognostic (1.76e-1)" "unprognostic (9.70e-3)" "unprognostic (1.11e-1)" "unprognostic (9.00e-2)" "validated prognostic favorable (1.58e-8)" "validated prognostic favorable (2.01e-4)" "potential prognostic favorable (5.49e-4)" "unprognostic (2.17e-1)" "unprognostic (1.96e-2)" "unprognostic (7.14e-3)" "unprognostic (2.49e-1)" "unprognostic (1.33e-2)" "unprognostic (2.56e-1)" "unprognostic (6.91e-2)" "unprognostic (2.83e-2)" "unprognostic (4.35e-2)" "unprognostic (1.49e-1)" "unprognostic (1.94e-1)" "unprognostic (4.97e-2)" "unprognostic (9.58e-2)" "unprognostic (3.70e-2)" "unprognostic (3.98e-3)" "unprognostic (1.98e-1)" "unprognostic (1.94e-1)" "unprognostic (3.56e-1)" FZD5 "C2orf31, DKFZP434E2135, HFZ5" ENSG00000163251 "Frizzled class receptor 5" Q13467 2 207762598-207769906 "G-protein coupled receptors, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" Microphthalmia "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 17.5;liver: 21.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 99.5;Alveolar cells type 2: 67.3;Colonocytes: 96.7;Enteric stem cells: 47.6;Enteric transient amplifying cells: 53.8;Foveolar cells: 61.7;Goblet cells: 51.3;Hepatocytes: 65.2;Müller glia: 56.6;Pituicytes/FSCs: 47.4" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 9.2;oligodendrocyte: 10.3" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 39.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA052361 Approved NA NA "Cluster 77: Intestine - Digestion" "Cluster 11: White matter - Signal transduction" "Cluster 18: Liver cancer - Metabolism" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 3 "HPA052361: " "unprognostic (1.08e-1)" "unprognostic (1.32e-1)" "unprognostic (2.43e-1)" "unprognostic (6.59e-2)" "unprognostic (3.06e-2)" "unprognostic (1.04e-2)" "unprognostic (2.33e-1)" "unprognostic (4.48e-2)" "unprognostic (1.58e-1)" "unprognostic (3.25e-2)" "potential prognostic favorable (1.07e-6)" "unprognostic (9.44e-3)" "unprognostic (4.54e-3)" "unprognostic (3.16e-3)" "unprognostic (4.76e-3)" "unprognostic (5.98e-2)" "unprognostic (1.56e-1)" "unprognostic (8.20e-2)" "unprognostic (1.43e-1)" "unprognostic (2.53e-3)" "unprognostic (1.67e-1)" "unprognostic (5.21e-2)" "unprognostic (6.49e-2)" "unprognostic (1.46e-1)" "unprognostic (6.16e-2)" "unprognostic (2.81e-1)" "unprognostic (2.01e-2)" "unprognostic (1.68e-1)" "unprognostic (1.08e-1)" "unprognostic (2.17e-1)" "unprognostic (3.69e-2)" FZD6 Hfz6 ENSG00000164930 "Frizzled class receptor 6" O60353 8 103298433-103332866 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 209.5;Endometrial luminal cells: 162.1" "Cell type enhanced" "Detected in all" "endothelial cell: 156.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "NK-cell: 4.0" "Lineage enriched" "Detected in single" 4 "NK-cells: 4.0" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Liver - Vascular endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017991 Approved Supported "Plasma membrane,Primary cilium,Basal body" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 14 "Plasma membrane" "Primary cilium, Basal body" "HPA017991: " "unprognostic (1.98e-2)" "unprognostic (1.87e-2)" "unprognostic (8.83e-2)" "unprognostic (1.63e-1)" "unprognostic (9.73e-2)" "unprognostic (7.50e-2)" "unprognostic (1.51e-2)" "unprognostic (4.25e-3)" "unprognostic (1.63e-2)" "unprognostic (1.77e-2)" "unprognostic (4.62e-2)" "unprognostic (1.77e-1)" "unprognostic (1.18e-1)" "unprognostic (7.09e-3)" "unprognostic (4.79e-3)" "unprognostic (2.77e-1)" "unprognostic (1.32e-1)" "unprognostic (8.83e-2)" "unprognostic (2.47e-1)" "unprognostic (5.72e-2)" "unprognostic (6.81e-3)" "validated prognostic unfavorable (6.43e-5)" "validated prognostic unfavorable (3.59e-6)" "unprognostic (8.02e-3)" "unprognostic (8.21e-2)" "unprognostic (8.80e-2)" "unprognostic (1.58e-1)" "unprognostic (1.28e-1)" "unprognostic (3.67e-1)" "unprognostic (4.62e-2)" "unprognostic (2.64e-1)" FZD7 FzE3 ENSG00000155760 "Frizzled class receptor 7" O75084 2 202033855-202038441 "G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 41.3;Breast secretory cells: 59.8;Lacrimal acinar cells: 29.9;Pituitary stem cells: 37.8;Respiratory ionocytes: 30.5;Salivary acinar cells: 25.8;Salivary myoepithelial cells: 32.6;Smooth muscle cells: 29.6" "Cell type enhanced" "Detected in many" "upper rhombic lip: 35.8;vascular associated smooth muscle cell: 24.1" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 60.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Liver - Hepatic stellate cells, Skin - Outer root sheath cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059979, HPA069165, HPA076183" Approved Supported Vesicles NA NA "Cluster 64: Non-specific - Transcription" "Cluster 35: Non-specific - DNA binding" "Cluster 5: Rhabdoid - Unknown function" "Cluster 108: Fibroblasts - ECM organization" 35 Vesicles "HPA059979: , HPA069165: , HPA076183: " "unprognostic (2.20e-3)" "unprognostic (8.09e-2)" "unprognostic (8.74e-2)" "unprognostic (1.80e-1)" "unprognostic (3.07e-2)" "unprognostic (2.21e-1)" "unprognostic (7.42e-2)" "unprognostic (3.97e-3)" "unprognostic (1.17e-1)" "unprognostic (8.77e-2)" "unprognostic (1.00e-2)" "unprognostic (5.20e-2)" "potential prognostic unfavorable (9.38e-8)" "potential prognostic unfavorable (6.01e-5)" "unprognostic (8.12e-2)" "unprognostic (1.42e-1)" "unprognostic (2.28e-1)" "unprognostic (1.33e-1)" "unprognostic (1.16e-2)" "unprognostic (4.30e-2)" "unprognostic (1.24e-2)" "unprognostic (1.73e-2)" "unprognostic (1.52e-1)" "unprognostic (1.68e-1)" "unprognostic (4.20e-1)" "unprognostic (8.20e-2)" "unprognostic (2.37e-2)" "unprognostic (1.80e-3)" "unprognostic (2.11e-1)" "unprognostic (2.25e-2)" "unprognostic (1.28e-1)" FZD8 ENSG00000177283 "Frizzled class receptor 8" Q9H461 10 35638247-35642296 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 18.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 58.1;Breast myoepithelial cells: 21.5;Choroid plexus epithelial cells: 19.7;Hepatic stellate cells: 19.4;Müller glia: 32.5;Parietal cells: 37.1;Pituicytes/FSCs: 28.5;Podocytes: 19.4;Thymic myoid cells: 43.5" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 23.1" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "choroid plexus: 85.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Spleen - Fibroblasts_1, Stomach - Parietal cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA045025, HPA071142" Approved Approved "Endoplasmic reticulum,Primary cilium" NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 3 "Endoplasmic reticulum" "Primary cilium" "HPA045025: , HPA071142: " "unprognostic (1.38e-1)" "unprognostic (7.58e-2)" "unprognostic (1.80e-2)" "unprognostic (1.21e-1)" "unprognostic (2.53e-2)" "unprognostic (1.14e-1)" "unprognostic (1.75e-2)" "unprognostic (1.83e-1)" "unprognostic (1.77e-1)" "unprognostic (8.59e-2)" "unprognostic (2.15e-2)" "potential prognostic favorable (4.17e-5)" "unprognostic (2.27e-2)" "unprognostic (1.61e-1)" "unprognostic (6.95e-3)" "unprognostic (2.20e-1)" "unprognostic (2.17e-1)" "unprognostic (8.26e-3)" "unprognostic (1.87e-2)" "unprognostic (2.41e-1)" "unprognostic (3.28e-1)" "unprognostic (1.07e-3)" "potential prognostic favorable (8.99e-4)" "unprognostic (2.61e-1)" "unprognostic (8.46e-3)" "unprognostic (1.97e-1)" "unprognostic (2.09e-1)" "unprognostic (2.51e-2)" "unprognostic (4.28e-2)" "potential prognostic unfavorable (4.44e-4)" "unprognostic (7.89e-2)" FZD9 "CD349, FZD3" ENSG00000188763 "Frizzled class receptor 9" O00144 7 73433778-73436120 "CD markers, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.3;skeletal muscle: 6.8;testis: 4.4" "Cell type enhanced" "Detected in some" "Early spermatids: 9.6;Gonadotrophs: 4.0;Granulosa cells: 4.1;Late spermatids: 20.6;Lymphatic endothelial cells: 6.1;Müller glia: 5.0;Oligodendrocyte progenitor cells: 18.2;Paneth cells: 19.3;Retinal ganglion cells: 3.9" "Group enriched" "Detected in many" 5 "fibroblast: 13.2;oligodendrocyte precursor cell: 19.5;pericyte: 10.2" "Cancer enriched" "Detected in many" 5 "Skin Cutaneous Melanoma (TCGA): 9.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" "unprognostic (1.18e-1)" "unprognostic (2.13e-2)" "unprognostic (1.66e-1)" "unprognostic (1.38e-1)" "unprognostic (1.71e-1)" "unprognostic (2.58e-1)" "unprognostic (2.29e-1)" "unprognostic (8.22e-2)" "unprognostic (1.43e-2)" FZR1 "CDC20C, CDH1, FZR, FZR2, HCDH, HCDH1, KIAA1242" ENSG00000105325 "Fizzy and cell division cycle 20 related 1" Q9UM11 19 3506311-3538334 "Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Mitosis, Ubl conjugation pathway" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 93.5;Late primary spermatocytes: 144.7;Late spermatids: 307.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043536 Approved Supported "Nucleoplasm,Nuclear membrane" NA Yes "Cluster 22: Eosinophils - Transcription" "Cluster 67: Testis - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 127 "Nucleoplasm, Nuclear membrane" "HPA043536: " "unprognostic (1.71e-1)" "unprognostic (8.31e-2)" "unprognostic (3.09e-1)" "unprognostic (6.63e-2)" "unprognostic (1.69e-1)" "unprognostic (3.10e-2)" "unprognostic (1.37e-1)" "unprognostic (4.16e-2)" "unprognostic (2.59e-2)" "unprognostic (2.69e-1)" "potential prognostic favorable (6.28e-4)" "unprognostic (7.85e-3)" "unprognostic (5.32e-2)" "unprognostic (9.94e-2)" "unprognostic (2.69e-2)" "unprognostic (9.23e-2)" "unprognostic (6.39e-3)" "unprognostic (9.13e-2)" "unprognostic (2.91e-1)" "unprognostic (1.36e-2)" "unprognostic (2.16e-1)" "unprognostic (1.27e-1)" "unprognostic (2.00e-2)" "unprognostic (4.22e-3)" "unprognostic (4.89e-2)" "unprognostic (6.91e-2)" "unprognostic (1.58e-1)" "unprognostic (3.10e-2)" "unprognostic (9.14e-2)" "unprognostic (4.81e-2)" "unprognostic (3.82e-2)" G0S2 ENSG00000123689 "G0/G1 switch 2" P27469 1 209675412-209676390 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 755.3;bone marrow: 1271.4" "Cell type enhanced" "Detected in many" "Breast lactating cells: 3431.4;cDC: 1751.5;Epididymal efferent duct absorptive cells: 680.6;monocytes: 1503.0;Neutrophils: 8172.8;Pancreatic acinar cells: 1619.2" "Cell type enhanced" "Detected in many" "fibroblast: 13.4;oligodendrocyte precursor cell: 15.0" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 188.7" "Region enriched" "Detected in all" 6 "cerebral cortex: 80.3" "Immune cell enriched" "Detected in some" 60 "neutrophil: 552.0" "Lineage enriched" "Detected in many" 213 "granulocytes: 552.0" "Cancer enhanced" "Detected in many" "thyroid cancer: 435.6" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Minor Salivary Gland - Adipocytes (Minor salivary gland), Skin - Adipocytes (Skin)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 12: Non-specific - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 7 "unprognostic (1.14e-1)" "unprognostic (4.41e-3)" "unprognostic (7.18e-3)" "unprognostic (4.18e-3)" "unprognostic (4.62e-3)" "unprognostic (1.21e-1)" "potential prognostic unfavorable (1.33e-5)" "unprognostic (4.77e-3)" "unprognostic (2.17e-1)" "unprognostic (2.44e-1)" "potential prognostic unfavorable (4.14e-4)" "unprognostic (3.74e-2)" "unprognostic (8.69e-3)" "unprognostic (2.59e-1)" "unprognostic (1.76e-1)" "unprognostic (1.13e-2)" "unprognostic (5.91e-2)" "unprognostic (1.47e-2)" "unprognostic (8.19e-2)" "unprognostic (1.69e-1)" "unprognostic (1.50e-1)" "unprognostic (2.95e-2)" "potential prognostic unfavorable (6.79e-4)" "unprognostic (6.35e-2)" "unprognostic (3.25e-3)" "unprognostic (1.57e-1)" "unprognostic (2.97e-1)" "unprognostic (6.23e-3)" "unprognostic (1.07e-2)" "unprognostic (1.07e-1)" "unprognostic (1.43e-2)" G2E3 "FLJ20333, KIAA1333, PHF7B" ENSG00000092140 "G2/M-phase specific E3 ubiquitin protein ligase" Q7L622 14 30559158-30620064 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Developmental protein, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 39.5" "Group enriched" "Detected in all" 5 "Early spermatids: 1181.9;Late spermatids: 356.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001601 Uncertain Approved "Golgi apparatus,Vesicles,Cytosol" NA Yes "Cluster 45: Eosinophils - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 9: Non-specific - Receptor signaling" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 8 Cytosol "Golgi apparatus, Vesicles" "HPA001601: " "unprognostic (1.62e-1)" "unprognostic (1.36e-1)" "unprognostic (4.38e-2)" "unprognostic (3.04e-2)" "unprognostic (3.84e-2)" "unprognostic (5.77e-2)" "unprognostic (1.41e-1)" "unprognostic (2.73e-2)" "unprognostic (1.07e-1)" "unprognostic (8.29e-3)" "potential prognostic favorable (6.74e-5)" "unprognostic (8.75e-2)" "unprognostic (2.36e-1)" "potential prognostic unfavorable (1.23e-4)" "unprognostic (8.78e-3)" "unprognostic (8.99e-3)" "unprognostic (9.78e-3)" "unprognostic (3.35e-1)" "unprognostic (2.54e-2)" "unprognostic (2.08e-1)" "unprognostic (3.76e-2)" "unprognostic (5.83e-3)" "potential prognostic unfavorable (1.58e-4)" "unprognostic (3.32e-1)" "unprognostic (3.70e-2)" "unprognostic (3.09e-1)" "unprognostic (9.66e-3)" "unprognostic (7.28e-2)" "unprognostic (9.68e-2)" "unprognostic (4.67e-2)" "unprognostic (5.32e-2)" G3BP1 "G3BP, HDH-VIII" ENSG00000145907 "G3BP stress granule assembly factor 1" Q13283 5 151771045-151812911 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction, Immunity, Innate immunity, Transport" "DNA-binding, Endonuclease, Helicase, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004052, CAB037068, HPA072698" Supported Enhanced Cytosol NA NA 220000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 17: Non-specific - RNA processing" 266 Cytosol "CAB037068: , HPA004052: , HPA072698: " "unprognostic (9.16e-2)" "unprognostic (1.36e-2)" "unprognostic (3.29e-1)" "unprognostic (3.54e-2)" "unprognostic (1.65e-2)" "unprognostic (8.28e-3)" "unprognostic (9.82e-2)" "unprognostic (9.90e-2)" "unprognostic (9.99e-3)" "potential prognostic unfavorable (1.27e-4)" "potential prognostic favorable (5.29e-6)" "unprognostic (1.42e-1)" "unprognostic (2.29e-3)" "potential prognostic unfavorable (2.12e-5)" "unprognostic (3.80e-2)" "potential prognostic unfavorable (2.55e-4)" "unprognostic (2.07e-3)" "unprognostic (6.60e-2)" "unprognostic (1.65e-1)" "unprognostic (2.82e-1)" "unprognostic (8.76e-3)" "unprognostic (5.58e-3)" "unprognostic (5.13e-2)" "unprognostic (3.35e-2)" "unprognostic (1.21e-2)" "unprognostic (4.49e-2)" "unprognostic (1.52e-1)" "unprognostic (1.19e-1)" "unprognostic (6.24e-2)" "unprognostic (1.16e-2)" "unprognostic (5.28e-2)" G3BP2 KIAA0660 ENSG00000138757 "G3BP stress granule assembly factor 2" Q9UN86 4 75641849-75724589 "Predicted intracellular proteins" "Host-virus interaction, Immunity, Innate immunity, mRNA transport, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Myonuclei: 795.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018304, HPA018425" Enhanced Enhanced Cytosol NA NA 19000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 9: T-cells - Adaptive immunity: Regulation" 274 Cytosol "HPA018304: , HPA018425: " "unprognostic (1.29e-1)" "unprognostic (1.33e-2)" "unprognostic (7.13e-2)" "unprognostic (2.43e-3)" "unprognostic (9.27e-3)" "unprognostic (1.19e-1)" "unprognostic (3.80e-1)" "unprognostic (1.50e-1)" "unprognostic (1.69e-1)" "potential prognostic unfavorable (9.23e-4)" "validated prognostic favorable (2.76e-7)" "validated prognostic favorable (1.99e-4)" "unprognostic (1.35e-1)" "unprognostic (2.39e-3)" "unprognostic (1.53e-2)" "unprognostic (1.12e-1)" "unprognostic (1.38e-2)" "unprognostic (5.77e-2)" "unprognostic (4.12e-2)" "unprognostic (1.35e-2)" "unprognostic (5.43e-2)" "unprognostic (9.02e-3)" "unprognostic (1.56e-1)" "unprognostic (8.86e-2)" "unprognostic (4.28e-2)" "unprognostic (3.15e-1)" "unprognostic (2.03e-1)" "unprognostic (1.75e-1)" "unprognostic (2.86e-1)" "unprognostic (1.06e-1)" "unprognostic (8.44e-2)" G6PC1 "G6PC, G6PT, GSD1a" ENSG00000131482 "Glucose-6-phosphatase catalytic subunit 1" P35575 17 42900797-42914438 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" Gluconeogenesis Hydrolase "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "kidney: 70.0;liver: 253.6" "Group enriched" "Detected in some" 4 "Enterocytes: 442.9;Hepatocytes: 466.4" "Cell type enhanced" "Detected in single" "Bergmann glia: 1.3" "Cancer enriched" "Detected in some" 37 "Liver Hepatocellular Carcinoma (TCGA): 161.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "liver cancer: 1.7" "Kidney - Proximal tubular cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA052324 Enhanced Approved "Mid piece" NA NA "Cluster 16: Liver & Kidney - Metabolism" "Cluster 6: Non-specific - Immune response" "Cluster 18: Liver cancer - Metabolism" "Cluster 93: Hepatocytes - Bile production & excretion" 2 "Mid piece" "HPA052324: " "validated prognostic favorable (1.75e-10)" "validated prognostic favorable (1.78e-8)" "unprognostic (2.24e-1)" "potential prognostic favorable (1.75e-4)" "unprognostic (2.60e-3)" "unprognostic (3.52e-3)" G6PC2 IGRP ENSG00000152254 "Glucose-6-phosphatase catalytic subunit 2" Q9NQR9 2 168901291-168910000 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Gluconeogenesis Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 70 "pancreas: 29.1;retina: 11.4" "Cell type enhanced" "Detected in some" "Oligodendrocyte progenitor cells: 1.2;Pancreatic islet cells: 1.8" "Cell type enhanced" "Detected in some" "endothelial cell: 2.2;hippocampal CA4: 2.6;hippocampal dentate gyrus: 3.7;pericyte: 2.2" "Cancer enriched" "Detected in single" 76 "Pancreatic Adenocarcinoma (TCGA): 11.9" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Beta cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 29: Forebrain - Mixed function" "Cluster 98: Neurons - Neurotransmission & signaling" "unprognostic (1.26e-1)" "unprognostic (7.73e-2)" G6PC3 UGRP ENSG00000141349 "Glucose-6-phosphatase catalytic subunit 3" Q9BUM1 17 44070620-44082151 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" Gluconeogenesis Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epicardial cells: 204.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067052 Supported "Endoplasmic reticulum" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 44: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 1 "Endoplasmic reticulum" "HPA067052: " "unprognostic (9.33e-2)" "unprognostic (2.45e-2)" "unprognostic (1.96e-1)" "unprognostic (1.84e-1)" "unprognostic (1.12e-1)" "unprognostic (9.50e-2)" "potential prognostic unfavorable (7.29e-4)" "unprognostic (1.24e-2)" "unprognostic (1.54e-1)" "unprognostic (1.68e-1)" "unprognostic (1.20e-3)" "potential prognostic unfavorable (1.48e-4)" "unprognostic (1.83e-1)" "potential prognostic unfavorable (4.17e-4)" "unprognostic (4.15e-3)" "unprognostic (1.49e-1)" "unprognostic (3.13e-1)" "unprognostic (1.11e-1)" "unprognostic (2.00e-1)" "unprognostic (1.01e-1)" "unprognostic (3.38e-1)" "unprognostic (6.64e-3)" "unprognostic (1.03e-2)" "unprognostic (1.03e-3)" "unprognostic (4.26e-1)" "unprognostic (1.37e-1)" "unprognostic (3.78e-1)" "unprognostic (1.94e-1)" "unprognostic (2.19e-1)" "unprognostic (5.57e-2)" "potential prognostic favorable (8.66e-4)" G6PD G6PD1 ENSG00000160211 "Glucose-6-phosphate dehydrogenase" P11413 X 154517825-154547572 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" Oxidoreductase "Cancer-related genes, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 135.2;Esophageal suprabasal cells: 163.7;Megakaryocytes: 136.0;Neutrophil progenitors: 148.2;Neutrophils: 141.1;Oocytes: 193.4;Platelets: 160.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 383.4" "Lineage enriched" "Detected in all" 5 "granulocytes: 383.4" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 839.6" "Colon - Macrophages, Heart muscle - Macrophages, Lung - Macrophages, Spleen - Neutrophils_2, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000247, HPA000834" Enhanced Supported "Centriolar satellite,Cytosol" No No 4900000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 21 Cytosol "Centriolar satellite" "HPA000247: , HPA000834: " "unprognostic (2.01e-1)" "unprognostic (1.42e-3)" "unprognostic (9.86e-2)" "unprognostic (2.30e-1)" "unprognostic (1.76e-1)" "unprognostic (5.92e-2)" "unprognostic (2.04e-1)" "unprognostic (2.31e-1)" "unprognostic (6.19e-2)" "unprognostic (1.86e-1)" "potential prognostic unfavorable (2.68e-4)" "unprognostic (6.84e-3)" "potential prognostic unfavorable (4.14e-5)" "validated prognostic unfavorable (2.01e-10)" "validated prognostic unfavorable (4.52e-5)" "unprognostic (7.26e-3)" "unprognostic (3.23e-1)" "unprognostic (9.07e-2)" "unprognostic (9.41e-2)" "unprognostic (1.27e-1)" "unprognostic (2.67e-2)" "unprognostic (2.07e-2)" "unprognostic (7.54e-2)" "unprognostic (2.85e-1)" "unprognostic (1.48e-1)" "unprognostic (6.44e-2)" "unprognostic (1.06e-1)" "unprognostic (2.36e-1)" "unprognostic (3.83e-2)" "unprognostic (4.47e-2)" "unprognostic (4.98e-2)" GAA ENSG00000171298 "Alpha glucosidase" P10253 17 80101556-80119881 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Disease variant, FDA approved drug targets, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 200.7;Epididymal principal cells: 135.2;Extravillous trophoblasts: 235.6;Kupffer cells: 163.0;Late primary spermatocytes: 142.9;Syncytiotrophoblasts: 198.2" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 99.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 66.6;eosinophil: 22.9;intermediate monocyte: 50.3;myeloid DC: 39.8;neutrophil: 27.1;non-classical monocyte: 69.0" "Group enriched" "Detected in all" 10 "dendritic cells: 39.8;granulocytes: 27.1;monocytes: 69.0" "Low cancer specificity" "Detected in all" "Lung - Macrophages, Spleen - Macrophages, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026970, HPA029126" Enhanced Approved Vesicles NA NA 5200000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 79: Testis - Spermatogenesis" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 27: Breast cancer - Unknown function" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 38 Vesicles "HPA026970: , HPA029126: " "unprognostic (7.79e-2)" "unprognostic (3.90e-2)" "unprognostic (5.84e-2)" "unprognostic (2.48e-2)" "unprognostic (9.18e-2)" "unprognostic (1.74e-2)" "unprognostic (3.09e-2)" "unprognostic (1.12e-1)" "unprognostic (1.35e-1)" "unprognostic (9.13e-2)" "unprognostic (7.29e-3)" "unprognostic (3.29e-3)" "unprognostic (6.43e-2)" "unprognostic (1.50e-2)" "unprognostic (6.82e-2)" "unprognostic (5.99e-3)" "unprognostic (8.95e-2)" "unprognostic (8.61e-2)" "unprognostic (3.71e-1)" "unprognostic (3.20e-2)" "unprognostic (2.65e-1)" "unprognostic (4.74e-2)" "unprognostic (2.18e-1)" "unprognostic (6.29e-2)" "unprognostic (7.76e-2)" "unprognostic (2.51e-2)" "unprognostic (2.92e-1)" "unprognostic (7.70e-2)" "unprognostic (2.20e-1)" "unprognostic (2.36e-3)" "unprognostic (3.25e-1)" GAB1 DFNB26 ENSG00000109458 "GRB2 associated binding protein 1" Q13480 4 143336876-143474565 "Disease related genes, Human disease related genes, Predicted intracellular proteins, RAS pathway related proteins" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 586.8;Oligodendrocytes: 1231.1;Plasma cells: 745.2" "Cell type enhanced" "Detected in all" "oligodendrocyte: 1748.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 4.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Hepatic stellate cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034333, HPA066404" Approved Approved "Nucleoli fibrillar center,Plasma membrane" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 6: Leukemia - Signal transduction" "Cluster 44: Plasma cells - Antibody production & secretion" 44 "Plasma membrane" "Nucleoli fibrillar center" "CAB034333: , HPA066404: " "unprognostic (5.86e-2)" "unprognostic (1.70e-1)" "unprognostic (6.17e-2)" "unprognostic (4.62e-2)" "unprognostic (2.71e-2)" "unprognostic (2.29e-3)" "unprognostic (3.98e-2)" "unprognostic (1.97e-1)" "unprognostic (6.36e-2)" "unprognostic (1.33e-1)" "validated prognostic favorable (3.42e-8)" "validated prognostic favorable (2.19e-6)" "unprognostic (9.98e-3)" "unprognostic (8.87e-2)" "unprognostic (8.09e-2)" "unprognostic (2.96e-1)" "unprognostic (5.23e-2)" "unprognostic (4.56e-1)" "unprognostic (1.12e-1)" "unprognostic (3.25e-2)" "unprognostic (2.15e-1)" "unprognostic (3.82e-2)" "unprognostic (7.47e-2)" "unprognostic (1.80e-1)" "unprognostic (1.91e-2)" "unprognostic (3.61e-2)" "unprognostic (9.37e-2)" "unprognostic (1.98e-1)" "unprognostic (1.46e-1)" "unprognostic (5.76e-2)" "unprognostic (5.54e-2)" GAB2 KIAA0571 ENSG00000033327 "GRB2 associated binding protein 2" Q9UQC2 11 78215293-78418348 "Predicted intracellular proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 54.0" "Cell type enhanced" "Detected in many" "Microglia: 774.7;monocytes: 1008.5;Neutrophils: 3649.1;Oligodendrocytes: 609.3;Thymocytes: 726.7" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 1026.5;oligodendrocyte: 836.4" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 63.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 13.1;neutrophil: 20.2" "Lineage enriched" "Detected in many" 4 "granulocytes: 20.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000271, HPA001368, CAB022159" Enhanced Supported "Plasma membrane" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 47: Leukemia - Hemostasis" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 37 "Plasma membrane" "CAB022159: , HPA000271: , HPA001368: " "unprognostic (3.10e-3)" "unprognostic (1.27e-1)" "unprognostic (4.57e-2)" "unprognostic (2.32e-2)" "unprognostic (1.98e-1)" "unprognostic (3.41e-2)" "unprognostic (1.18e-2)" "unprognostic (2.77e-3)" "unprognostic (7.64e-2)" "unprognostic (3.85e-2)" "validated prognostic favorable (6.27e-7)" "validated prognostic favorable (5.86e-4)" "unprognostic (2.46e-1)" "unprognostic (1.69e-2)" "unprognostic (2.62e-1)" "potential prognostic favorable (8.37e-4)" "unprognostic (3.11e-1)" "potential prognostic unfavorable (5.94e-5)" "unprognostic (1.39e-1)" "unprognostic (5.81e-1)" "unprognostic (2.03e-1)" "unprognostic (1.75e-1)" "unprognostic (1.05e-1)" "unprognostic (1.77e-1)" "unprognostic (9.51e-2)" "unprognostic (5.27e-2)" "unprognostic (1.11e-2)" "unprognostic (6.22e-2)" "unprognostic (2.95e-1)" "unprognostic (2.41e-1)" "unprognostic (3.19e-2)" GAB3 ENSG00000160219 "GRB2 associated binding protein 3" Q8WWW8 X 154675249-154751583 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 13.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 203.5;cDC: 69.0;Erythrocyte progenitors: 128.7;Hematopoietic stem cells: 74.2;Macrophages: 87.3;Mast cells: 72.2;Megakaryocyte progenitors: 217.8;Megakaryocyte-Erythroid progenitors: 126.5;Microglia: 158.1;monocytes: 78.6;Neutrophils: 110.6;NK-cells: 95.1;Sertoli cells: 111.4" "Group enriched" "Detected in many" 4 "central nervous system macrophage: 202.5;leukocyte: 126.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 11.4" "Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA010090 Approved Approved "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 11: White matter - Signal transduction" "Cluster 47: Leukemia - Hemostasis" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 1 "Nuclear speckles" "Nucleoplasm, Cytosol" "HPA010090: " "unprognostic (3.29e-1)" "unprognostic (9.64e-3)" "unprognostic (6.85e-2)" "unprognostic (3.45e-2)" "unprognostic (2.46e-1)" "unprognostic (1.89e-1)" "unprognostic (7.79e-2)" "unprognostic (4.91e-2)" "unprognostic (6.99e-2)" "unprognostic (1.51e-1)" "unprognostic (1.75e-2)" "potential prognostic favorable (9.26e-5)" "unprognostic (1.34e-1)" "unprognostic (2.72e-1)" "unprognostic (1.73e-1)" "unprognostic (1.96e-1)" "unprognostic (1.05e-2)" "unprognostic (1.18e-2)" "unprognostic (6.06e-2)" "unprognostic (7.01e-2)" "unprognostic (1.52e-2)" "unprognostic (2.56e-1)" GAB4 ENSG00000215568 "GRB2 associated binding protein family member 4" Q2WGN9 22 16961936-17008222 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 10 "testis: 1.9" "Cell type enhanced" "Detected in some" "Early primary spermatocytes: 3.8;Early spermatids: 9.2;Late primary spermatocytes: 10.9;Late spermatids: 42.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" HPA044621 Uncertain NA NA "Cluster 67: Testis - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" "HPA044621: " GABARAP "ATG8A, MM46" ENSG00000170296 "GABA type A receptor-associated protein" O95166 17 7240008-7242449 "Predicted intracellular proteins, Transporters" "Apoptosis, Autophagy, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 268.2;Enteric stem cells: 212.7;Enteric transient amplifying cells: 204.7;Enterocytes: 334.8;Epididymal clear cells: 185.8;Epididymal efferent duct absorptive cells: 205.6;Epididymal efferent duct ciliated cells: 207.3;Epididymal principal cells: 235.3;Gastric chief cells: 340.7;Goblet cells: 247.0;Mucous neck cells: 185.2;Neuroendocrine cells: 252.7;Parietal cells: 371.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065883 Supported Vesicles NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 15: Non-specific - Protein processing" 105 Vesicles "HPA065883: " "unprognostic (3.16e-1)" "unprognostic (2.20e-1)" "unprognostic (1.55e-1)" "potential prognostic favorable (1.53e-4)" "unprognostic (3.42e-1)" "unprognostic (7.24e-2)" "unprognostic (3.71e-1)" "unprognostic (1.63e-2)" "unprognostic (1.71e-1)" "unprognostic (3.70e-2)" "potential prognostic favorable (3.78e-4)" "unprognostic (9.09e-3)" "unprognostic (2.23e-3)" "unprognostic (3.37e-2)" "unprognostic (3.99e-1)" "unprognostic (4.10e-1)" "unprognostic (2.11e-1)" "unprognostic (2.15e-1)" "unprognostic (1.34e-1)" "unprognostic (2.53e-1)" "unprognostic (1.04e-1)" "unprognostic (2.90e-3)" "unprognostic (9.68e-2)" "unprognostic (6.80e-2)" "unprognostic (1.99e-2)" "unprognostic (2.40e-1)" "unprognostic (2.97e-2)" "unprognostic (6.69e-2)" "unprognostic (5.55e-2)" "unprognostic (3.13e-1)" "unprognostic (1.72e-1)" GABARAPL1 "APG8L, ATG8B, ATG8L, gec1" ENSG00000139112 "GABA type A receptor associated protein like 1" Q9H0R8 12 10212458-10223128 "Predicted intracellular proteins" "Autophagy, Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 380.8;Syncytiotrophoblasts: 1337.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 447.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 62.4" "Group enriched" "Detected in many" 5 "granulocytes: 62.4;NK-cells: 22.6;T-cells: 26.8" "Cancer enriched" "Detected in all" 5 "testis cancer: 513.0" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051386, HPA065883" Approved Supported "Vesicles,Plasma membrane,Primary cilium,Basal body,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 76: Non-specific - Metabolism" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 129 Vesicles "Plasma membrane, Primary cilium, Basal body, Cytosol" "HPA051386: , HPA065883: " "unprognostic (3.63e-2)" "unprognostic (7.21e-2)" "unprognostic (4.65e-2)" "unprognostic (4.59e-1)" "unprognostic (2.63e-1)" "unprognostic (1.78e-3)" "unprognostic (9.14e-2)" "unprognostic (1.13e-2)" "unprognostic (5.85e-3)" "unprognostic (2.20e-1)" "validated prognostic favorable (8.56e-6)" "validated prognostic favorable (7.86e-5)" "unprognostic (1.92e-1)" "unprognostic (1.71e-3)" "unprognostic (3.43e-2)" "unprognostic (2.83e-2)" "unprognostic (1.50e-1)" "unprognostic (1.87e-1)" "unprognostic (3.02e-1)" "unprognostic (1.27e-2)" "unprognostic (1.82e-1)" "unprognostic (1.95e-1)" "unprognostic (4.76e-3)" "unprognostic (1.71e-1)" "unprognostic (3.85e-2)" "unprognostic (1.61e-2)" "unprognostic (1.30e-1)" "unprognostic (6.71e-3)" "unprognostic (9.94e-2)" "unprognostic (4.12e-2)" "unprognostic (2.94e-1)" GABARAPL2 "ATG8, ATG8C, GATE-16, GATE16, GEF2" ENSG00000034713 "GABA type A receptor associated protein like 2" P60520 16 75566375-75577881 "Predicted intracellular proteins" "Autophagy, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1141.6;Platelets: 692.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036726 Uncertain Uncertain "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 22000 "Cluster 21: Neutrophils - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 27: Non-specific - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 97: Non-specific - Cellular respiration" 136 "Nucleoplasm, Cytosol" "Nuclear bodies" "HPA036726: " "unprognostic (1.91e-1)" "unprognostic (4.86e-3)" "unprognostic (7.96e-2)" "unprognostic (3.23e-2)" "unprognostic (4.30e-2)" "unprognostic (1.01e-1)" "unprognostic (2.08e-2)" "unprognostic (1.25e-1)" "potential prognostic unfavorable (8.40e-4)" "unprognostic (6.12e-2)" "potential prognostic favorable (2.62e-7)" "unprognostic (4.46e-3)" "unprognostic (2.92e-2)" "unprognostic (9.38e-2)" "unprognostic (7.17e-2)" "unprognostic (1.56e-1)" "unprognostic (1.88e-2)" "unprognostic (1.12e-1)" "unprognostic (1.01e-1)" "unprognostic (2.10e-1)" "unprognostic (3.70e-3)" "unprognostic (4.42e-2)" "unprognostic (1.31e-1)" "unprognostic (1.90e-1)" "unprognostic (1.27e-1)" "unprognostic (2.56e-1)" "unprognostic (3.14e-1)" "potential prognostic unfavorable (6.62e-4)" "unprognostic (6.78e-2)" "unprognostic (8.44e-2)" "unprognostic (3.10e-2)" GABBR1 "GPRC3A, hGB1a" ENSG00000204681 "Gamma-aminobutyric acid type B receptor subunit 1" Q9UBS5 6 29555629-29633976 "FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 224.4" "Cell type enhanced" "Detected in some" "Astrocytes: 293.4;Bergmann glia: 307.7;Brain excitatory neurons: 97.1;Brain inhibitory neurons: 122.5;Choroid plexus epithelial cells: 41.5;Ependymal cells: 72.9;Oligodendrocyte progenitor cells: 120.7;Other brain neurons: 94.5;Podocytes: 67.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050483 Uncertain Approved "Vesicles,Plasma membrane,Primary cilium tip,Basal body" "Intracellular and membrane" Receptor NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 98: Neurons - Neurotransmission & signaling" 13 "Vesicles, Plasma membrane" "Primary cilium tip, Basal body" "HPA050483: " "unprognostic (1.47e-1)" "unprognostic (1.21e-1)" "unprognostic (3.41e-1)" "unprognostic (3.21e-1)" "unprognostic (1.85e-2)" "unprognostic (2.21e-1)" "unprognostic (1.33e-1)" "potential prognostic favorable (5.87e-5)" "unprognostic (3.27e-2)" "potential prognostic unfavorable (7.31e-7)" "unprognostic (2.47e-2)" "unprognostic (2.53e-1)" "potential prognostic favorable (5.06e-5)" "unprognostic (1.22e-2)" "unprognostic (1.02e-1)" "unprognostic (1.54e-2)" "unprognostic (9.51e-2)" "unprognostic (4.62e-2)" "unprognostic (1.15e-2)" "unprognostic (1.97e-3)" "unprognostic (1.35e-2)" "unprognostic (2.53e-1)" "unprognostic (1.57e-1)" "unprognostic (8.89e-2)" "unprognostic (2.78e-1)" "unprognostic (1.84e-1)" "unprognostic (4.55e-2)" "unprognostic (1.47e-1)" GABBR2 "GABABR2, GPR51, GPRC3B, HG20" ENSG00000136928 "Gamma-aminobutyric acid type B receptor subunit 2" O75899 9 98288109-98708935 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, Epilepsy, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "brain: 62.4" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 371.5;Brain inhibitory neurons: 252.5;Early spermatids: 236.3;Late spermatids: 66.5;Oocytes: 69.1;Other brain neurons: 125.4;Retinal amacrine cells: 195.1;Retinal bipolar cells: 255.2;Retinal ganglion cells: 77.3" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in some" 9 "Bladder Urothelial Carcinoma (TCGA): 6.9;Glioblastoma Multiforme (TCGA): 12.3;Thyroid Carcinoma (TCGA): 17.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "thyroid cancer: 8.9" "Pituitary gland - Undifferentiated cells (Pituitary gland), Skin - Smooth muscle cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013820, HPA031684, CAB079065" Enhanced Approved NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 9 "CAB079065: , HPA013820: , HPA031684: " "unprognostic (6.06e-2)" "unprognostic (3.72e-1)" "unprognostic (8.43e-3)" "unprognostic (9.94e-2)" "unprognostic (5.70e-1)" "unprognostic (1.76e-2)" "unprognostic (2.63e-1)" "unprognostic (4.26e-2)" GABPA "E4TF1-60, E4TF1A, NFT2, NRF2, NRF2A" ENSG00000154727 "GA binding protein transcription factor subunit alpha" Q06546 21 25734570-25772460 "Essential proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 164.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003258, CAB004411, HPA028791" Supported Enhanced Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 47: Leukemia - Hemostasis" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 24 Nucleoplasm "CAB004411: , HPA003258: , HPA028791: " "unprognostic (2.23e-1)" "unprognostic (7.01e-2)" "unprognostic (1.05e-1)" "unprognostic (9.37e-2)" "unprognostic (1.12e-1)" "unprognostic (1.06e-3)" "unprognostic (1.61e-1)" "unprognostic (4.68e-1)" "unprognostic (3.98e-2)" "unprognostic (4.10e-2)" "validated prognostic favorable (1.87e-6)" "validated prognostic favorable (8.56e-4)" "unprognostic (6.51e-3)" "unprognostic (1.29e-1)" "unprognostic (2.50e-1)" "unprognostic (9.93e-2)" "unprognostic (1.04e-1)" "unprognostic (1.92e-1)" "unprognostic (7.33e-2)" "unprognostic (1.98e-2)" "unprognostic (4.16e-2)" "unprognostic (1.09e-1)" "unprognostic (1.55e-1)" "unprognostic (2.20e-1)" "unprognostic (7.66e-2)" "unprognostic (2.14e-1)" "unprognostic (9.30e-2)" "unprognostic (1.67e-1)" "unprognostic (1.89e-1)" "unprognostic (1.20e-2)" "unprognostic (1.93e-1)" GABPB1 "E4TF1-47, GABPB, GABPB2" ENSG00000104064 "GA binding protein transcription factor subunit beta 1" Q06547 15 50275389-50355408 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 177.7;Innate lymphoid cells: 188.7;Mast cells: 346.4;Neutrophils: 276.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019653, HPA067444" Supported Supported "Nucleoplasm,Cytoplasmic bodies" NA Yes "Cluster 3: Non-specific - Nuclear processes" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 25: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 23 Nucleoplasm "Cytoplasmic bodies" "HPA019653: , HPA067444: " "unprognostic (4.22e-1)" "unprognostic (8.59e-2)" "unprognostic (1.84e-1)" "unprognostic (8.15e-2)" "unprognostic (2.07e-1)" "unprognostic (1.33e-2)" "unprognostic (1.74e-1)" "unprognostic (7.89e-2)" "unprognostic (2.81e-1)" "potential prognostic unfavorable (8.85e-4)" "unprognostic (2.07e-2)" "unprognostic (1.77e-1)" "unprognostic (3.57e-2)" "unprognostic (6.07e-3)" "unprognostic (6.91e-3)" "unprognostic (2.13e-3)" "potential prognostic unfavorable (3.13e-4)" "unprognostic (2.36e-1)" "unprognostic (3.26e-1)" "unprognostic (5.23e-2)" "unprognostic (1.19e-1)" "unprognostic (1.02e-1)" "potential prognostic unfavorable (4.58e-4)" "unprognostic (1.57e-2)" "unprognostic (4.45e-2)" "unprognostic (5.34e-3)" "unprognostic (2.40e-3)" "unprognostic (1.89e-1)" "unprognostic (4.35e-1)" "unprognostic (1.74e-1)" "unprognostic (5.66e-1)" GABPB2 MGC29891 ENSG00000143458 "GA binding protein transcription factor subunit beta 2" Q8TAK5 1 151070578-151125542 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 232.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028471, HPA058483" Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 55: Myocytes - Oxidative muscle function" 11 Nucleoplasm Cytosol "HPA028471: , HPA058483: " "unprognostic (2.68e-3)" "unprognostic (4.46e-2)" "unprognostic (3.67e-2)" "unprognostic (3.17e-1)" "unprognostic (2.56e-1)" "unprognostic (2.06e-1)" "unprognostic (8.08e-2)" "unprognostic (3.59e-1)" "unprognostic (6.70e-2)" "unprognostic (1.77e-1)" "unprognostic (3.32e-2)" "potential prognostic favorable (1.57e-4)" "unprognostic (3.68e-2)" "unprognostic (7.72e-2)" "unprognostic (1.00e-1)" "unprognostic (3.62e-1)" "unprognostic (2.33e-1)" "unprognostic (9.09e-2)" "unprognostic (1.81e-1)" "unprognostic (1.76e-1)" "unprognostic (5.28e-2)" "unprognostic (2.15e-1)" "unprognostic (4.73e-2)" "unprognostic (1.07e-1)" "unprognostic (1.47e-1)" "unprognostic (1.86e-1)" "unprognostic (1.34e-3)" "unprognostic (3.00e-2)" "unprognostic (3.06e-1)" "unprognostic (1.41e-1)" "unprognostic (1.44e-1)" GABRA1 EJM5 ENSG00000022355 "Gamma-aminobutyric acid type A receptor subunit alpha1" P14867 5 161847063-161899981 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 30 "brain: 52.4;retina: 16.5" "Group enriched" "Detected in some" 7 "Brain excitatory neurons: 184.1;Brain inhibitory neurons: 156.6;Other brain neurons: 71.8;Retinal bipolar cells: 224.8" "Cell type enhanced" "Detected in all" "cerebellar inhibitory: 583.1" "Cancer enhanced" "Detected in single" "Glioblastoma Multiforme (TCGA): 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "breast cancer: 3.7" "Adrenal gland - Adrenal medulla cells, Skin - Inner root sheath cells, Stomach - Gastric enteroendocrine cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022502, HPA029363, HPA055746" Enhanced Supported Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 53: Neurons - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 109: Neurons - Neuronal signaling" 14 "Plasma membrane" Nucleoplasm "CAB022502: , HPA029363: , HPA055746: " "unprognostic (1.08e-1)" "unprognostic (1.27e-1)" GABRA2 ENSG00000151834 "Gamma-aminobutyric acid type A receptor subunit alpha2" P47869 4 46243548-46475230 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 37.3" "Cell type enhanced" "Detected in many" "Astrocytes: 448.7;Bergmann glia: 1024.6;Brain excitatory neurons: 186.5;Brain inhibitory neurons: 257.8;Other brain neurons: 199.3;Renal collecting duct principal cells: 98.4;Retinal amacrine cells: 228.2" "Cell type enhanced" "Detected in all" "Bergmann glia: 1113.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 7.6" "Breast - Endothelial cells, Pituitary gland - Somatotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029363, CAB079061" Supported Approved "Nucleoplasm,Plasma membrane" "Intracellular and membrane" Receptor NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 35: Neurons - Synaptic function & neurogenesis" 3 "Plasma membrane" Nucleoplasm "CAB079061: , HPA029363: " "unprognostic (6.84e-2)" "unprognostic (6.00e-3)" "unprognostic (1.92e-2)" "unprognostic (3.72e-2)" "unprognostic (1.82e-1)" "unprognostic (1.36e-1)" "unprognostic (1.27e-3)" "unprognostic (1.22e-1)" GABRA3 ENSG00000011677 "Gamma-aminobutyric acid type A receptor subunit alpha3" P34903 X 152166234-152451315 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 16.4;choroid plexus: 32.1;retina: 8.3" "Cell type enhanced" "Detected in many" "Adipocytes: 36.1;Brain excitatory neurons: 54.7;Brain inhibitory neurons: 47.9;Choroid plexus epithelial cells: 223.9;Hofbauer cells: 98.4;Oligodendrocyte progenitor cells: 73.8;Other brain neurons: 61.6;Retinal amacrine cells: 57.3;Undifferentiated spermatogonia: 28.3" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 6 "Testicular Germ Cell Tumor (TCGA): 26.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enteroendocrine cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000839, HPA029363" Approved Supported Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 101: Choroid plexus epithelial cells - Ion transport" "Plasma membrane" Nucleoplasm "HPA000839: , HPA029363: " "unprognostic (1.26e-3)" "unprognostic (2.28e-1)" "unprognostic (7.92e-2)" "potential prognostic favorable (9.98e-5)" "unprognostic (1.63e-1)" "unprognostic (2.42e-1)" "unprognostic (2.37e-1)" "unprognostic (1.20e-1)" "unprognostic (1.94e-1)" "unprognostic (3.86e-2)" "unprognostic (2.21e-1)" "unprognostic (1.60e-3)" "unprognostic (5.85e-2)" GABRA4 ENSG00000109158 "Gamma-aminobutyric acid type A receptor subunit alpha4" P48169 4 46918900-46993581 "FDA approved drug targets, Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 9.3;heart muscle: 2.4" "Cell type enhanced" "Detected in some" "Astrocytes: 36.5;Bergmann glia: 131.4;Brain excitatory neurons: 74.9;Brain inhibitory neurons: 152.5;Cardiomyocytes: 51.5;Corticotrophs: 24.4;Lactotrophs: 57.4;Other brain neurons: 59.3;Thyrotrophs: 35.5" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Smooth muscle cells, Colon - Colon enteroendocrine cells, Pituitary gland - Lactotropes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 35: Neurons - Synaptic function & neurogenesis" "unprognostic (2.25e-1)" GABRA5 ENSG00000186297 "Gamma-aminobutyric acid type A receptor subunit alpha5" P31644 15 26866911-26949208 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "brain: 121.7" "Cell type enriched" "Detected in some" 6 "Retinal bipolar cells: 381.5" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Glioblastoma Multiforme (TCGA): 2.4;Lung Squamous Cell Carcinoma (TCGA): 1.4;Skin Cutaneous Melanoma (TCGA): 1.6;Testicular Germ Cell Tumor (TCGA): 2.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Rhabdoid: 22.0" "Pituitary gland - Corticotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA029363, HPA077031, CAB079022" Supported Supported "Nucleoplasm,Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "Plasma membrane" "Nucleoplasm, Actin filaments, Cytosol" "CAB079022: , HPA029363: , HPA077031: " "unprognostic (1.45e-1)" "unprognostic (5.29e-2)" "unprognostic (9.13e-2)" "unprognostic (1.46e-1)" "unprognostic (4.71e-2)" GABRA6 ENSG00000145863 "Gamma-aminobutyric acid type A receptor subunit alpha6" Q16445 5 161547063-161702593 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 264 "brain: 185.8" "Group enriched" "Detected in some" 6 "Brain excitatory neurons: 87.7;Brain inhibitory neurons: 26.2;Epicardial cells: 27.3;Sertoli cells: 23.7" "Cell type enhanced" "Detected in many" "upper rhombic lip: 194.6" "Not detected" "Not detected" "Region enriched" "Detected in many" 14 "cerebellum: 150.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Sertoli cells" "Region enriched" "Detected in some" 40 "cerebellum: 1073.9" "Region enriched" "Detected in some" 39 "cerebellum: 263.8" CAB022462 Approved NA NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 1: Neuronal - Visual perception" "Cluster 2: Cerebellar granular cells - Neuronal signaling" "CAB022462: " GABRB1 ENSG00000163288 "Gamma-aminobutyric acid type A receptor subunit beta1" P18505 4 46993723-47426447 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 12.9;heart muscle: 3.4" "Cell type enhanced" "Detected in many" "Astrocytes: 1325.8;Bergmann glia: 2573.4;Brain excitatory neurons: 481.8;Brain inhibitory neurons: 653.9;Corticotrophs: 317.6;Lactotrophs: 476.8;Müller glia: 259.1;Oligodendrocyte progenitor cells: 332.3;Other brain neurons: 739.4;Somatotrophs: 360.5;Thyrotrophs: 384.6" "Cell type enhanced" "Detected in all" "Bergmann glia: 2822.9" "Cancer enriched" "Detected in single" 6 "Glioblastoma Multiforme (TCGA): 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Minor Salivary Gland - Minor salivary glandular cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 28: Astrocytes - Homeostasis & neuron support" 1 "unprognostic (3.02e-2)" "unprognostic (3.05e-1)" GABRB2 ENSG00000145864 "Gamma-aminobutyric acid type A receptor subunit beta2" P47870 5 161288429-161549044 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 41.3" "Group enriched" "Detected in many" 4 "Brain excitatory neurons: 714.2;Brain inhibitory neurons: 494.5;Respiratory ionocytes: 558.8" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in some" 18 "Thyroid Carcinoma (TCGA): 20.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 1.8" "Adipose subcutaneous - Macrophages, Minor Salivary Gland - Minor salivary gland ductal cells, Stomach - Parietal cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001964, HPA067632" Enhanced NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 53: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 3 "CAB001964: , HPA067632: " "unprognostic (7.57e-3)" "unprognostic (1.61e-3)" "unprognostic (3.28e-2)" "unprognostic (1.53e-1)" "unprognostic (2.09e-2)" "unprognostic (8.55e-3)" GABRB3 ENSG00000166206 "Gamma-aminobutyric acid type A receptor subunit beta3" P28472 15 26543552-26939539 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 44.1;retina: 28.0" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 649.5;Brain inhibitory neurons: 612.9;Corticotrophs: 800.3;Gonadotrophs: 507.6;Lactotrophs: 489.7;Other brain neurons: 430.4;Retinal amacrine cells: 450.2;Retinal bipolar cells: 2411.3;Retinal ganglion cells: 316.7;Retinal horizontal cells: 332.6;Rod photoreceptor cells: 450.0;Somatotrophs: 381.1;Thyrotrophs: 733.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 47.4" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 2 "unprognostic (1.47e-1)" "unprognostic (1.63e-1)" "unprognostic (1.50e-1)" "unprognostic (2.78e-1)" "unprognostic (4.24e-2)" "potential prognostic favorable (2.55e-4)" "validated prognostic favorable (7.47e-9)" "validated prognostic favorable (8.18e-4)" "unprognostic (8.44e-3)" "unprognostic (1.33e-1)" "unprognostic (2.87e-1)" "unprognostic (1.10e-1)" "unprognostic (9.51e-2)" "unprognostic (6.07e-2)" "unprognostic (1.24e-1)" "unprognostic (3.25e-2)" "unprognostic (4.82e-2)" "unprognostic (2.93e-1)" "unprognostic (1.17e-1)" "unprognostic (2.72e-1)" "unprognostic (8.64e-3)" "unprognostic (1.25e-1)" "unprognostic (8.12e-2)" GABRD ENSG00000187730 "Gamma-aminobutyric acid type A receptor subunit delta" O14764 1 2019329-2030758 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 73 "brain: 274.2" "Cell type enhanced" "Detected in some" "Bergmann glia: 13.5;Brain excitatory neurons: 76.4;Brain inhibitory neurons: 33.5;Differentiating spermatogonia: 18.5;Platelets: 12.7;Retinal amacrine cells: 18.9;Retinal bipolar cells: 10.7;Retinal horizontal cells: 12.0;Undifferentiated spermatogonia: 13.6" "Cell type enhanced" "Detected in many" "LAMP5-LHX6 and Chandelier: 138.2;upper rhombic lip: 165.5" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 12.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 2.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044371 Enhanced Uncertain "Golgi apparatus,Vesicles" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 37: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 13 "Golgi apparatus, Vesicles" "HPA044371: " "potential prognostic unfavorable (7.19e-6)" "unprognostic (3.31e-3)" "unprognostic (1.59e-1)" "unprognostic (7.05e-2)" "unprognostic (1.50e-3)" "unprognostic (1.96e-2)" "unprognostic (3.25e-1)" "validated prognostic favorable (1.20e-4)" "validated prognostic favorable (2.26e-4)" "unprognostic (4.20e-2)" "unprognostic (2.30e-2)" "unprognostic (1.07e-1)" "unprognostic (1.04e-1)" "unprognostic (4.25e-2)" "unprognostic (2.00e-2)" "unprognostic (1.62e-1)" "potential prognostic unfavorable (5.28e-6)" "unprognostic (1.72e-1)" "unprognostic (2.54e-1)" "unprognostic (2.91e-1)" GABRE ENSG00000102287 "Gamma-aminobutyric acid type A receptor subunit epsilon" P78334 X 151953124-151974680 "FDA approved drug targets, Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 9.1;brain: 13.5;heart muscle: 8.9" "Cell type enhanced" "Detected in many" "Adipocytes: 398.4;Basal prostatic cells: 70.6;Pituicytes/FSCs: 107.8;Prostatic hillock cells: 89.4;Syncytiotrophoblasts: 105.6" "Cell type enhanced" "Detected in many" "fibroblast: 26.5;pericyte: 48.6;vascular associated smooth muscle cell: 25.6" "Low cancer specificity" "Detected in some" "Group enriched" "Detected in many" 5 "cerebral cortex: 33.2;hypothalamus: 103.9;midbrain: 81.8;pons: 74.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Endothelial cells, Pituitary gland - Endothelial cells, Spleen - Fibroblasts_1" "Region enriched" "Detected in many" 4 "hypothalamus: 18.5" "Region enhanced" "Detected in many" "hypothalamus: 45.2" HPA045918 Uncertain NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 7: Liver cancer - Metabolism" "Cluster 89: Adipocytes - Lipid metabolism" 6 "HPA045918: " "potential prognostic favorable (2.81e-4)" "unprognostic (1.18e-2)" "unprognostic (5.81e-2)" "unprognostic (2.95e-1)" "unprognostic (9.26e-2)" "unprognostic (1.02e-1)" "unprognostic (2.11e-2)" "unprognostic (1.50e-1)" "unprognostic (4.31e-2)" "unprognostic (7.07e-2)" "potential prognostic unfavorable (1.12e-4)" "unprognostic (3.74e-2)" GABRG1 ENSG00000163285 "Gamma-aminobutyric acid type A receptor subunit gamma1" Q8N1C3 4 46035769-46124054 "FDA approved drug targets, Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 20.9" "Cell type enhanced" "Detected in some" "Astrocytes: 158.3;Bergmann glia: 275.5;Brain inhibitory neurons: 36.8;Ependymal cells: 383.4;Epididymal efferent duct ciliated cells: 37.8;Other brain neurons: 78.0;Retinal amacrine cells: 88.2" "Cell type enhanced" "Detected in many" "Bergmann glia: 350.0;ependymal cell: 484.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Adrenocortical cancer: 1.4;Myeloma: 2.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035622, HPA058102" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 11: Neuronal - Sensory perception" "Cluster 34: Ciliated cells - Cilia assembly & function" 1 "Plasma membrane" Vesicles "HPA035622: , HPA058102: " "unprognostic (1.42e-2)" GABRG2 ENSG00000113327 "Gamma-aminobutyric acid type A receptor subunit gamma2" P18507 5 162000057-162162977 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 40.7;retina: 10.3" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 42.5;Brain excitatory neurons: 215.9;Brain inhibitory neurons: 204.7;Corticotrophs: 105.3;Lactotrophs: 81.9;Other brain neurons: 161.1;Retinal amacrine cells: 80.8;Retinal bipolar cells: 136.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 15.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 4.6" "Group enriched" "Detected in many" 5 "B-cells: 1.6;granulocytes: 4.6;T-cells: 1.5" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 36.0" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pituitary gland - Lactotropes, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB079060 Supported NA NA "Cluster 32: Basophils - Transcription" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 3 "CAB079060: " "unprognostic (1.67e-2)" "unprognostic (7.78e-3)" "unprognostic (6.36e-3)" "unprognostic (4.92e-3)" "unprognostic (1.24e-1)" "unprognostic (8.49e-2)" "unprognostic (9.03e-2)" "unprognostic (1.25e-3)" "unprognostic (2.71e-2)" "unprognostic (1.07e-1)" "potential prognostic unfavorable (6.93e-5)" "potential prognostic unfavorable (7.18e-4)" "unprognostic (8.59e-2)" "unprognostic (1.37e-2)" "unprognostic (3.26e-1)" "unprognostic (1.56e-1)" "unprognostic (3.35e-1)" "unprognostic (2.94e-2)" "unprognostic (2.87e-2)" "unprognostic (7.02e-2)" "unprognostic (1.51e-2)" "unprognostic (2.78e-1)" "unprognostic (1.94e-1)" "unprognostic (3.77e-3)" GABRG3 ENSG00000182256 "Gamma-aminobutyric acid type A receptor subunit gamma3" Q99928 15 26971181-27541984 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "prostate: 6.2;retina: 25.1;testis: 8.6" "Cell type enhanced" "Detected in many" "Bergmann glia: 908.0;Brain excitatory neurons: 294.6;Brain inhibitory neurons: 525.3;Ependymal cells: 296.5;Lactotrophs: 387.6;Late spermatids: 332.2;Müller glia: 1541.1;Other brain neurons: 683.3;Pituicytes/FSCs: 287.2;Pituitary stem cells: 291.9;Prostatic glandular cells: 482.2;Somatotrophs: 341.1;Thyrotrophs: 728.8" "Cell type enhanced" "Detected in all" "eccentric medium spiny neuron: 1425.8" "Cancer enhanced" "Detected in some" "Prostate Adenocarcinoma (TCGA): 9.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "thyroid cancer: 3.1" "Adrenal gland - Adrenal medulla cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA054010 Approved Approved "Nucleoli,Plasma membrane,Microtubules" NA NA "Cluster 42: Retina - Visual perception" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" "Plasma membrane, Microtubules" Nucleoli "HPA054010: " "unprognostic (1.76e-1)" "unprognostic (9.49e-2)" "unprognostic (2.54e-2)" "unprognostic (2.74e-1)" "unprognostic (1.06e-1)" "unprognostic (2.18e-2)" "unprognostic (1.51e-1)" GABRP ENSG00000094755 "Gamma-aminobutyric acid type A receptor subunit pi" O00591 5 170763350-170814047 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 142.2;esophagus: 161.4" "Cell type enhanced" "Detected in many" "Breast lactating cells: 118.5;Breast secretory cells: 360.7;Endometrial glandular cells: 559.4;Endometrial luminal cells: 633.7;Esophageal apical cells: 399.0;Prostatic hillock cells: 129.2;Respiratory secretory cells: 145.2;Salivary duct cells: 316.6;Submucosal glandular cells: 183.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 11.8" "Group enriched" "Detected in many" 8 "granulocytes: 11.8;monocytes: 5.8" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Prostate - Urothelial cells, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" CAB014883 Uncertain NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 3: Rhabdoid - Membrane components" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" "CAB014883: " "unprognostic (1.13e-2)" "unprognostic (1.36e-2)" "unprognostic (1.77e-1)" "unprognostic (4.09e-3)" "unprognostic (1.61e-3)" "unprognostic (1.58e-3)" "unprognostic (1.98e-3)" "unprognostic (2.70e-1)" "unprognostic (1.41e-1)" "potential prognostic unfavorable (3.22e-4)" "unprognostic (1.43e-1)" "unprognostic (5.20e-2)" "unprognostic (1.50e-1)" "unprognostic (3.23e-1)" "unprognostic (1.43e-1)" "unprognostic (3.92e-2)" "unprognostic (2.36e-2)" "unprognostic (7.99e-2)" "unprognostic (2.77e-2)" "unprognostic (8.17e-2)" "potential prognostic unfavorable (1.75e-4)" "unprognostic (2.87e-1)" "unprognostic (2.87e-1)" "unprognostic (3.68e-2)" "unprognostic (4.03e-2)" "unprognostic (1.76e-1)" "unprognostic (7.97e-2)" "unprognostic (2.58e-1)" "unprognostic (5.75e-3)" "unprognostic (1.04e-2)" GABRQ ENSG00000268089 "Gamma-aminobutyric acid type A receptor subunit theta" Q9UN88 X 152637895-152657542 "FDA approved drug targets, Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 20.8;cervix: 7.2" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 10.6;Basal keratinocytes: 5.9;Brain excitatory neurons: 7.9;Brain inhibitory neurons: 6.2;Endometrial glandular cells: 4.7;Oligodendrocyte progenitor cells: 3.5;Other brain neurons: 23.5;Retinal amacrine cells: 10.3" "Cell type enhanced" "Detected in many" "eccentric medium spiny neuron: 79.3;hippocampal dentate gyrus: 31.2" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 9.3" "Region enhanced" "Detected in many" "hypothalamus: 154.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 7.1;Brain cancer: 7.3" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells" "Region enriched" "Detected in many" 5 "hypothalamus: 52.6" "Group enriched" "Detected in many" 4 "hypothalamus: 12.4;midbrain: 33.1;pons: 10.2" NA NA "Cluster 65: Brain - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 72: Neuronal - Signal transduction" "Cluster 35: Neurons - Synaptic function & neurogenesis" 3 "unprognostic (3.21e-3)" "potential prognostic unfavorable (9.58e-5)" "unprognostic (1.78e-1)" "unprognostic (2.73e-1)" "unprognostic (1.41e-1)" "unprognostic (1.23e-3)" "unprognostic (1.63e-1)" "potential prognostic favorable (7.96e-4)" "unprognostic (4.50e-1)" GABRR1 ENSG00000146276 "Gamma-aminobutyric acid type A receptor subunit rho1" P24046 6 89177504-89231278 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 15 "retina: 22.8" "Cell type enriched" "Detected in some" 20 "Retinal bipolar cells: 188.9" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Lung Squamous Cell Carcinoma (TCGA): 2.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Bone cancer: 3.3;thyroid cancer: 12.8" "Region enhanced" "Detected in single" "midbrain: 1.3" "Low region specificity" "Detected in many" NA NA "Cluster 42: Retina - Visual perception" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 1 "unprognostic (9.57e-2)" "potential prognostic favorable (3.28e-4)" "unprognostic (1.88e-1)" GABRR2 ENSG00000111886 "Gamma-aminobutyric acid type A receptor subunit rho2" P28476 6 89254464-89315299 "Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 9 "retina: 29.1" "Cell type enriched" "Detected in many" 13 "Retinal bipolar cells: 799.3" "Cell type enhanced" "Detected in many" "endothelial cell: 7.8;midbrain-derived inhibitory: 22.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "Myeloma: 5.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 42: Retina - Visual perception" "Cluster 6: Non-specific - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "unprognostic (8.21e-2)" "unprognostic (9.04e-2)" "unprognostic (9.94e-3)" "unprognostic (3.07e-2)" GABRR3 ENSG00000183185 "Gamma-aminobutyric acid type A receptor subunit rho3" A8MPY1 3 97985102-98035315 "Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 71 "retina: 8.1" "Group enriched" "Detected in some" 23 "Retinal bipolar cells: 119.3;Rod photoreceptor cells: 41.0" "Cell type enhanced" "Detected in some" "lower rhombic lip: 3.3;upper rhombic lip: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 42: Retina - Visual perception" "Cluster 1: Neuronal - Visual perception" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" GAD1 GAD ENSG00000128683 "Glutamate decarboxylase 1" Q99259 2 170813213-170861151 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Neurotransmitter biosynthesis" "Decarboxylase, Lyase" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "brain: 69.1;parathyroid gland: 43.4;retina: 27.5" "Group enriched" "Detected in many" 4 "Brain inhibitory neurons: 309.1;Distal convoluted tubule cells: 161.0;Oligodendrocyte progenitor cells: 137.0;Other brain neurons: 168.8;Retinal amacrine cells: 421.3" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 469.2;CGE interneuron: 438.2;MGE interneuron: 554.5;midbrain-derived inhibitory: 529.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Smooth muscle cells, Pituitary gland - Somatotropes" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "olfactory bulb: 546.3" "CAB004415, HPA048871, HPA058412, CAB078176" Enhanced Supported Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 32: Non-specific - Cell proliferation" "Cluster 109: Neurons - Neuronal signaling" 7 "Vesicles, Plasma membrane, Cytosol" "CAB004415: , CAB078176: , HPA048871: , HPA058412: " "unprognostic (8.12e-2)" "unprognostic (2.82e-1)" "unprognostic (2.34e-1)" "potential prognostic favorable (5.23e-4)" "unprognostic (9.83e-2)" "unprognostic (2.64e-2)" "unprognostic (2.11e-1)" "unprognostic (2.85e-3)" "unprognostic (1.83e-1)" "unprognostic (5.16e-2)" "potential prognostic unfavorable (7.41e-4)" "unprognostic (9.87e-2)" "unprognostic (2.18e-2)" "unprognostic (1.45e-1)" "unprognostic (1.14e-2)" "unprognostic (4.89e-2)" "unprognostic (1.95e-2)" "unprognostic (2.31e-2)" "unprognostic (1.60e-3)" "unprognostic (3.69e-2)" "unprognostic (2.73e-2)" "unprognostic (3.78e-2)" "unprognostic (1.66e-2)" "potential prognostic unfavorable (6.80e-4)" "unprognostic (3.97e-1)" "unprognostic (1.67e-3)" "unprognostic (1.22e-1)" "potential prognostic favorable (4.28e-4)" GAD2 GAD65 ENSG00000136750 "Glutamate decarboxylase 2" Q05329 10 26216665-26304558 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Neurotransmitter biosynthesis" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 65.4" "Cell type enhanced" "Detected in some" "Brain inhibitory neurons: 384.9;Oocytes: 110.5;Other brain neurons: 145.9;Pancreatic islet cells: 547.0;Retinal amacrine cells: 179.0" "Group enriched" "Detected in all" 23 "cerebellar inhibitory: 446.8;CGE interneuron: 533.6;eccentric medium spiny neuron: 254.3;LAMP5-LHX6 and Chandelier: 772.9;medium spiny neuron: 397.4;MGE interneuron: 455.0;midbrain-derived inhibitory: 705.5;splatter: 193.3" "Group enriched" "Detected in some" 22 "Glioblastoma Multiforme (TCGA): 1.4;Pancreatic Adenocarcinoma (TCGA): 4.5;Testicular Germ Cell Tumor (TCGA): 1.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 13 "lung cancer: 1.2" "Pancreas - Beta cells, Pituitary gland - Gonadotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044637, CAB078177" Enhanced NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 36 "CAB078177: , HPA044637: " "unprognostic (1.16e-1)" "unprognostic (1.27e-1)" "unprognostic (2.46e-2)" "unprognostic (6.26e-2)" "unprognostic (9.72e-2)" GADD45A "DDIT1, GADD45" ENSG00000116717 "Growth arrest and DNA damage inducible alpha" P24522 1 67685201-67688334 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, DNA damage, Growth arrest" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 635.6;Endometrial glandular cells: 1252.3;Endometrial secretory cells: 966.2;Epididymal basal cells: 2899.7;Epididymal clear cells: 996.2;Epididymal efferent duct absorptive cells: 958.4;Epididymal efferent duct ciliated cells: 794.5;Fallopian secretory cells: 675.2;Urothelial cells: 877.7" "Cell type enhanced" "Detected in many" "endothelial cell: 44.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 48.5" "Group enriched" "Detected in all" 5 "granulocytes: 48.5;T-cells: 18.6" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053420 Supported "Nuclear speckles" NA Yes "Cluster 19: Eosinophils - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 27: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 51: Secretory epithelial cells - Mixed function" 37 "Nuclear speckles" "HPA053420: " "unprognostic (2.16e-2)" "unprognostic (4.80e-2)" "unprognostic (3.13e-1)" "unprognostic (3.76e-2)" "unprognostic (7.98e-2)" "unprognostic (1.40e-1)" "unprognostic (5.48e-2)" "unprognostic (4.23e-2)" "unprognostic (2.71e-2)" "unprognostic (1.03e-1)" "potential prognostic favorable (8.80e-6)" "unprognostic (3.96e-2)" "unprognostic (2.37e-1)" "unprognostic (3.81e-3)" "unprognostic (5.99e-3)" "unprognostic (2.21e-3)" "unprognostic (1.76e-3)" "unprognostic (8.66e-2)" "unprognostic (3.02e-2)" "unprognostic (1.36e-1)" "unprognostic (3.20e-1)" "unprognostic (1.95e-2)" "unprognostic (2.74e-2)" "unprognostic (1.53e-1)" "unprognostic (5.69e-2)" "unprognostic (1.44e-2)" "unprognostic (1.78e-1)" "unprognostic (1.78e-1)" "unprognostic (2.49e-1)" "unprognostic (5.97e-2)" "unprognostic (4.10e-2)" GADD45B "DKFZP566B133, GADD45BETA, MYD118" ENSG00000099860 "Growth arrest and DNA damage inducible beta" O75293 19 2476122-2478259 "Predicted intracellular proteins" "Apoptosis, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 1200.9;Breast myoepithelial cells: 1949.5;Endometrial luminal cells: 1493.3;Epididymal basal cells: 2078.3;Smooth muscle cells: 1588.3;Vascular smooth muscle cells: 2536.8" "Cell type enhanced" "Detected in many" "astrocyte: 126.0;endothelial cell: 102.1;vascular associated smooth muscle cell: 244.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Neutrophils" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 21.4" "HPA029816, HPA063918" Approved Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 44: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 103: Non-specific - Basic cellular processes" 10 Nucleoplasm "Nucleoli, Cytosol" "HPA029816: , HPA063918: " "unprognostic (9.74e-3)" "unprognostic (3.32e-2)" "unprognostic (8.25e-2)" "unprognostic (3.54e-1)" "unprognostic (2.61e-2)" "unprognostic (4.88e-2)" "unprognostic (7.04e-3)" "unprognostic (2.47e-2)" "unprognostic (2.42e-3)" "unprognostic (2.76e-2)" "unprognostic (6.75e-2)" "unprognostic (3.72e-2)" "unprognostic (1.11e-1)" "unprognostic (6.64e-3)" "unprognostic (1.17e-2)" "unprognostic (2.66e-2)" "unprognostic (1.12e-1)" "potential prognostic unfavorable (6.44e-4)" "unprognostic (1.34e-1)" "unprognostic (8.45e-3)" "unprognostic (9.83e-2)" "unprognostic (2.93e-1)" "unprognostic (5.27e-2)" "unprognostic (2.37e-1)" "unprognostic (9.57e-2)" "potential prognostic favorable (9.91e-4)" "unprognostic (1.14e-2)" "unprognostic (1.60e-3)" "unprognostic (1.42e-1)" "unprognostic (4.12e-3)" "unprognostic (4.40e-2)" GADD45G "CR6, DDIT2, GADD45gamma, GRP17" ENSG00000130222 "Growth arrest and DNA damage inducible gamma" O95257 9 89605012-89606555 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Differentiation" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 313.6;liver: 333.6" "Cell type enriched" "Detected in many" 4 "Syncytiotrophoblasts: 1977.2" "Cell type enhanced" "Detected in all" "astrocyte: 33.3" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 124.9;Prostate Adenocarcinoma (TCGA): 151.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "eosinophil: 4.9" "Lineage enriched" "Detected in single" 24 "granulocytes: 4.9" "Cancer enhanced" "Detected in many" "prostate cancer: 26.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023606 Approved NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 70: Non-specific - Protein processing" "Cluster 25: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 53 "HPA023606: " "unprognostic (1.44e-1)" "unprognostic (9.80e-2)" "unprognostic (1.34e-1)" "unprognostic (2.26e-3)" "unprognostic (8.30e-2)" "unprognostic (2.35e-3)" "unprognostic (4.98e-2)" "potential prognostic favorable (1.55e-4)" "unprognostic (1.37e-1)" "unprognostic (2.78e-2)" "unprognostic (2.00e-1)" "unprognostic (3.31e-2)" "potential prognostic favorable (1.61e-4)" "unprognostic (9.13e-3)" "unprognostic (2.68e-3)" "potential prognostic favorable (6.73e-4)" "unprognostic (6.34e-2)" "unprognostic (4.14e-3)" "unprognostic (1.30e-1)" "potential prognostic favorable (8.47e-4)" "unprognostic (3.02e-2)" "potential prognostic favorable (1.60e-4)" "unprognostic (1.79e-1)" "unprognostic (2.27e-1)" "unprognostic (1.84e-2)" "potential prognostic unfavorable (7.70e-4)" "unprognostic (1.96e-1)" "unprognostic (1.51e-1)" "unprognostic (4.47e-2)" "unprognostic (5.66e-2)" "unprognostic (3.54e-2)" GADD45GIP1 "CKBBP2, CKbetaBP2, CRIF1, MGC4667, MGC4758, PLINP-1, Plinp1, PRG6" ENSG00000179271 "GADD45G interacting protein 1" Q8TAE8 19 12953119-12957223 "Predicted intracellular proteins, Ribosomal proteins" "Cell cycle, Host-virus interaction" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 569.5;Esophageal suprabasal cells: 582.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055205, HPA065048, HPA071910" Supported Supported Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 204 Mitochondria "HPA055205: , HPA065048: , HPA071910: " "unprognostic (2.11e-1)" "unprognostic (7.89e-2)" "unprognostic (8.22e-2)" "unprognostic (6.88e-2)" "unprognostic (4.22e-2)" "unprognostic (2.44e-1)" "unprognostic (2.88e-2)" "unprognostic (4.58e-1)" "unprognostic (1.98e-1)" "unprognostic (3.11e-1)" "unprognostic (1.58e-3)" "unprognostic (1.05e-2)" "unprognostic (5.48e-2)" "unprognostic (8.51e-3)" "unprognostic (1.13e-3)" "unprognostic (2.61e-2)" "unprognostic (4.43e-2)" "unprognostic (9.93e-3)" "unprognostic (2.12e-1)" "unprognostic (1.28e-3)" "unprognostic (5.18e-2)" "unprognostic (3.05e-1)" "unprognostic (1.81e-1)" "unprognostic (4.13e-2)" "unprognostic (3.24e-1)" "unprognostic (6.09e-2)" "unprognostic (2.20e-1)" "unprognostic (3.29e-1)" "unprognostic (5.63e-2)" "unprognostic (3.04e-2)" "unprognostic (1.02e-1)" GADL1 ENSG00000144644 "Glutamate decarboxylase like 1" Q6ZQY3 3 30726197-30894661 "Enzymes, Predicted intracellular proteins" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 12 "skeletal muscle: 24.7;tongue: 10.8" "Cell type enriched" "Detected in some" 4 "Myonuclei: 151.9" "Group enriched" "Detected in some" 9 "fibroblast: 47.5;lower rhombic lip: 28.4;mammillary body: 27.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose visceral - Mesothelial cells, Kidney - Ascending Loop of Henle cells, Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA039160, HPA040229" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 9: Non-specific - Receptor signaling" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 46: Skeletal myocytes - Muscle structure & formation" "Plasma membrane, Cytosol" "HPA039160: , HPA040229: " "unprognostic (1.41e-2)" "unprognostic (2.42e-1)" "unprognostic (1.27e-2)" "unprognostic (1.52e-2)" "unprognostic (4.10e-2)" "unprognostic (1.13e-1)" "potential prognostic unfavorable (1.26e-4)" GAGE1 CT4.1 ENSG00000205777 "G antigen 1" P0DTW1 X 49599020-49608538 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "testis: 1.7" "Group enriched" "Detected in some" 77 "Differentiating spermatogonia: 151.8;Early primary spermatocytes: 54.0;Undifferentiated spermatogonia: 46.9" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Gallbladder cancer: 14.2;liver cancer: 3.7" "Testis - Spermatogonia" HPA043232 Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 47: Testis - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 1 "Plasma membrane" "Golgi apparatus, Cytosol" "HPA043232: " "potential prognostic unfavorable (1.18e-9)" "unprognostic (2.83e-1)" "unprognostic (8.84e-2)" "unprognostic (6.45e-3)" "unprognostic (7.48e-2)" "unprognostic (2.95e-1)" GAGE10 ENSG00000215274 "G antigen 10" A6NGK3 X 49303646-49319841 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "testis: 1.5" "Cell type enhanced" "Detected in some" "Corticotrophs: 8.7;Differentiating spermatogonia: 5.7;Early primary spermatocytes: 9.9;Ependymal cells: 11.7;Gonadotrophs: 8.4;Granulosa cells: 5.7;Lactotrophs: 10.8;Megakaryocytes: 6.2;Pituitary stem cells: 7.9;Somatotrophs: 8.1;Thyrotrophs: 16.2" "Cell type enhanced" "Detected in many" "ependymal cell: 10.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 2.5" HPA043232 Supported Uncertain "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 21: Testis - Mixed function" "Cluster 33: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 1 "Plasma membrane" "Golgi apparatus, Cytosol" "HPA043232: " "unprognostic (1.60e-2)" "potential prognostic unfavorable (1.49e-8)" "unprognostic (5.08e-1)" "unprognostic (1.41e-1)" "unprognostic (5.08e-1)" GAGE12B ENSG00000236737 "G antigen 12B" X 49529869-49529985 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 49 "testis: 132.5" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "Ovary Serous Cystadenocarcinoma (TCGA): 14.2;Stomach Adenocarcinoma (TCGA): 4.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 79: Testis - Spermatogenesis" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 49: HMC-1 - Innate immune response" "unprognostic (6.16e-1)" "unprognostic (1.32e-1)" GAGE12C ENSG00000237671 "G antigen 12C" A1L429 X 49532177-49539538 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 222 "testis: 22.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 32.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "liver cancer: 11.6;Myeloma: 42.8" HPA043232 Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" 1 "Plasma membrane" "Golgi apparatus, Cytosol" "HPA043232: " "unprognostic (3.20e-2)" "unprognostic (4.04e-1)" "unprognostic (6.29e-1)" GAGE12D ENSG00000227488 "G antigen 12D" A1L429 X 49541733-49549094 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 222 "testis: 22.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 32.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "liver cancer: 11.6;Myeloma: 42.8" HPA043232 Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" 1 "Plasma membrane" "Golgi apparatus, Cytosol" "HPA043232: " "unprognostic (3.20e-2)" "unprognostic (4.04e-1)" "unprognostic (6.29e-1)" GAGE12E ENSG00000216649 "G antigen 12E" A1L429 X 49551289-49558645 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 137 "testis: 13.7" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney Chromophobe (TCGA): 2.0;Stomach Adenocarcinoma (TCGA): 2.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "liver cancer: 89.9;Myeloma: 136.7" HPA043232 Supported Uncertain "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" 1 "Plasma membrane" "Golgi apparatus, Cytosol" "HPA043232: " GAGE12F ENSG00000236362 "G antigen 12F" "P0CL80, O76087, P0CL82" X 49551278-49568218 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "testis: 99.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 279.1" HPA043232 Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 33: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" 1 "Plasma membrane" "Golgi apparatus, Cytosol" "HPA043232: " "unprognostic (6.10e-1)" "unprognostic (3.97e-1)" "unprognostic (2.28e-1)" "potential prognostic unfavorable (6.45e-9)" "unprognostic (6.03e-1)" "unprognostic (5.15e-1)" "unprognostic (2.57e-3)" "unprognostic (4.23e-2)" "unprognostic (1.30e-1)" "unprognostic (4.20e-2)" "unprognostic (5.14e-2)" "unprognostic (1.69e-2)" "unprognostic (2.35e-1)" "unprognostic (4.00e-1)" GAGE12G ENSG00000215269 "G antigen 12G" "P0CL81, O76087, P0CL82" X 49570400-49577754 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "testis: 57.9" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 8.7" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 208.8" HPA043232 Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" 1 "Plasma membrane" "Golgi apparatus, Cytosol" "HPA043232: " "unprognostic (1.81e-1)" "unprognostic (8.95e-1)" "unprognostic (4.20e-2)" GAGE12H ENSG00000224902 "G antigen 12H" A6NDE8 X 49579949-49587301 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 232 "testis: 23.2" "Group enriched" "Detected in some" 8 "Differentiating spermatogonia: 5.7;Early primary spermatocytes: 2.6;Undifferentiated spermatogonia: 2.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 27.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "Bone cancer: 31.0;liver cancer: 72.7;Myeloma: 98.7" HPA043232 Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 106: Spermatogonia - Spermatogonial differentiation" "Plasma membrane" "Golgi apparatus, Cytosol" "HPA043232: " "unprognostic (7.56e-1)" "unprognostic (8.90e-1)" GAGE12J GAGE11 ENSG00000224659 "G antigen 12J" A6NER3 X 49322037-49329384 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "testis: 21.6" "Cell type enriched" "Detected in single" 7 "Differentiating spermatogonia: 1.1" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 21.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 59.7;Myeloma: 87.5" HPA043232 Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 106: Spermatogonia - Spermatogonial differentiation" "Plasma membrane" "Golgi apparatus, Cytosol" "HPA043232: " "unprognostic (6.65e-1)" "potential prognostic unfavorable (2.01e-5)" "unprognostic (3.36e-1)" "unprognostic (5.90e-1)" "unprognostic (6.28e-3)" "unprognostic (2.45e-1)" "unprognostic (2.18e-1)" "unprognostic (9.97e-2)" GAGE13 GAGE12A ENSG00000274274 "G antigen 13" Q4V321 X 49331582-49338949 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 37 "testis: 51.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 159.8;liver cancer: 224.7;skin cancer: 137.4" HPA043232 Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Plasma membrane" "Golgi apparatus, Cytosol" "HPA043232: " "unprognostic (2.14e-1)" "unprognostic (1.60e-1)" "potential prognostic unfavorable (2.27e-8)" "unprognostic (6.26e-1)" "unprognostic (4.32e-2)" "unprognostic (1.03e-1)" "unprognostic (8.84e-2)" "unprognostic (7.75e-2)" "unprognostic (4.85e-1)" "unprognostic (1.89e-1)" GAGE2A "CT4.2, GAGE2" ENSG00000189064 "G antigen 2A" Q6NT46 X 49589496-49596824 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 116 "testis: 89.2" "Group enriched" "Detected in some" 62 "Differentiating spermatogonia: 498.9;Early primary spermatocytes: 213.8;Undifferentiated spermatogonia: 145.9" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Gallbladder cancer: 786.9;liver cancer: 216.0" HPA043232 Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 106: Spermatogonia - Spermatogonial differentiation" "Plasma membrane" "Golgi apparatus, Cytosol" "HPA043232: " "unprognostic (5.17e-2)" "validated prognostic unfavorable (2.00e-9)" "validated prognostic unfavorable (5.66e-4)" "unprognostic (3.72e-1)" "unprognostic (1.44e-3)" "unprognostic (8.44e-2)" "unprognostic (3.87e-1)" "unprognostic (3.64e-1)" "unprognostic (2.38e-3)" "unprognostic (2.46e-2)" "unprognostic (3.04e-1)" GAGE2E GAGE8 ENSG00000275113 "G antigen 2E" Q4V326 X 49341192-49345922 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 14 "stomach 1: 14.5;testis: 52.4" "Cell type enhanced" "Detected in single" "Differentiating spermatogonia: 1.1" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 90.9" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "T-reg: 3.0" "Group enriched" "Detected in many" 4 "B-cells: 1.0;T-cells: 3.0" "Cancer enhanced" "Detected in many" "Bone cancer: 135.1;skin cancer: 179.6" HPA043232 Approved Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 19: Astrocytes - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 106: Spermatogonia - Spermatogonial differentiation" "Plasma membrane" "Golgi apparatus, Cytosol" "HPA043232: " "unprognostic (1.18e-1)" "unprognostic (6.17e-1)" "unprognostic (2.64e-2)" "potential prognostic unfavorable (8.42e-8)" "unprognostic (2.98e-1)" "unprognostic (6.66e-2)" "unprognostic (3.88e-1)" "unprognostic (8.87e-2)" "unprognostic (3.47e-3)" "unprognostic (7.27e-2)" "unprognostic (2.40e-1)" "unprognostic (2.68e-1)" GAK DNAJC26 ENSG00000178950 "Cyclin G associated kinase" O14976 4 849276-932373 "Enzymes, Essential proteins, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 201.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027405, HPA027459, HPA027463" Approved Supported "Golgi apparatus,Vesicles" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 40 "Golgi apparatus" Vesicles "HPA027405: , HPA027459: , HPA027463: " "unprognostic (6.62e-2)" "unprognostic (6.30e-2)" "unprognostic (1.69e-1)" "unprognostic (3.16e-2)" "unprognostic (4.34e-2)" "unprognostic (1.09e-2)" "unprognostic (2.12e-1)" "unprognostic (1.04e-2)" "unprognostic (1.49e-2)" "unprognostic (1.30e-1)" "unprognostic (1.05e-3)" "unprognostic (4.38e-2)" "potential prognostic favorable (1.12e-5)" "unprognostic (3.07e-2)" "unprognostic (3.82e-1)" "unprognostic (1.75e-1)" "unprognostic (2.11e-1)" "unprognostic (5.13e-2)" "unprognostic (1.51e-2)" "unprognostic (3.48e-1)" "potential prognostic favorable (1.65e-5)" "unprognostic (2.10e-2)" "unprognostic (3.14e-1)" "unprognostic (1.62e-2)" "unprognostic (9.17e-3)" "unprognostic (9.73e-2)" "unprognostic (2.80e-1)" "unprognostic (9.44e-3)" "unprognostic (3.55e-1)" "unprognostic (2.94e-1)" "unprognostic (4.73e-2)" GAL "GAL-GMAP, GALN, GLNN, GMAP" ENSG00000069482 "Galanin and GMAP prepropeptide" P22466 11 68683779-68691175 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Hormone, Neuropeptide" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "pituitary gland: 957.4" "Group enriched" "Detected in many" 4 "Corticotrophs: 666.4;Gonadotrophs: 236.8" "Cell type enhanced" "Detected in many" "hippocampal CA4: 23.5;splatter: 11.2;thalamic excitatory: 12.0" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 54.2" "Region enriched" "Detected in all" 13 "hypothalamus: 1423.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 257.1" "Colon - Colon enteroendocrine cells, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Corticotropes, Skin - Sebaceous gland cells" "Region enhanced" "Detected in many" "hypothalamus: 82.6" "Low region specificity" "Detected in many" "HPA049864, CAB079779" Enhanced Supported Approved "Golgi apparatus,Vesicles" "Secreted to blood" Hormone NA NA 60000 140000 "Cluster 20: Pituitary gland - Hormone signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 13 "Golgi apparatus" Vesicles "CAB079779: , HPA049864: " "unprognostic (3.23e-2)" "unprognostic (5.68e-2)" "unprognostic (4.12e-3)" "unprognostic (6.96e-2)" "unprognostic (4.51e-3)" "unprognostic (6.06e-2)" "unprognostic (3.41e-1)" "unprognostic (3.01e-1)" "unprognostic (2.69e-2)" "unprognostic (2.79e-1)" "potential prognostic unfavorable (1.32e-4)" "unprognostic (8.51e-2)" "unprognostic (1.71e-2)" "unprognostic (2.90e-1)" "unprognostic (7.75e-3)" "unprognostic (1.26e-1)" "unprognostic (8.23e-2)" "unprognostic (5.77e-2)" "unprognostic (6.89e-2)" "unprognostic (3.59e-1)" "unprognostic (8.84e-3)" "unprognostic (1.31e-1)" "unprognostic (1.44e-1)" "unprognostic (1.02e-1)" "unprognostic (1.24e-3)" GAL3ST1 CST ENSG00000128242 "Galactose-3-O-sulfotransferase 1" Q99999 22 30554635-30574665 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Sphingolipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 66.3;intestine: 22.9;kidney: 22.2" "Cell type enhanced" "Detected in many" "Cholangiocytes: 21.8;Colonocytes: 17.0;Distal convoluted tubule cells: 19.8;Early primary spermatocytes: 23.0;Enterocytes: 48.5;Loop of henle epithelial cells: 24.0;Müller glia: 43.6;Oligodendrocyte progenitor cells: 45.2;Oligodendrocytes: 70.8;Paneth cells: 19.3;Schwann cells: 22.6" "Group enriched" "Detected in many" 8 "committed oligodendrocyte precursor: 84.8;oligodendrocyte: 82.4;oligodendrocyte precursor cell: 48.6" "Group enriched" "Detected in many" 6 "Kidney Renal Clear Cell Carcinoma (TCGA): 180.4;Kidney Renal Papillary Cell Carcinoma (TCGA): 62.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 16 "Kidney cancer: 235.5" "Adipose visceral - Mesothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001220, HPA077138" Approved Uncertain Nucleoplasm,Vesicles NA NA 6600 "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 15: Kidney cancer - Membrane components" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" Vesicles Nucleoplasm "HPA001220: , HPA077138: " "unprognostic (4.60e-2)" "unprognostic (2.09e-1)" "unprognostic (4.71e-2)" "unprognostic (2.10e-1)" "unprognostic (8.98e-2)" "unprognostic (3.25e-1)" "unprognostic (7.69e-2)" "unprognostic (4.46e-2)" "unprognostic (9.61e-3)" "unprognostic (1.77e-1)" "unprognostic (2.83e-2)" "unprognostic (1.15e-2)" "unprognostic (1.11e-3)" "unprognostic (2.47e-1)" "unprognostic (3.22e-3)" "unprognostic (5.59e-2)" "unprognostic (2.21e-1)" "unprognostic (1.27e-1)" "unprognostic (1.14e-1)" "unprognostic (8.49e-2)" "unprognostic (4.27e-3)" "unprognostic (2.04e-1)" "potential prognostic unfavorable (3.68e-4)" "unprognostic (3.74e-2)" "unprognostic (1.33e-1)" "unprognostic (8.00e-2)" "unprognostic (1.00e-1)" GAL3ST2 GP3ST ENSG00000154252 "Galactose-3-O-sulfotransferase 2" Q9H3Q3 2 241776822-241804287 "Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 11 "intestine: 8.8" "Cell type enhanced" "Detected in some" "Colonocytes: 3.9;Conjunctival goblet cells: 3.9;Enteric stem cells: 4.0;Enteric transient amplifying cells: 3.6;Ependymal cells: 4.0;Goblet cells: 4.2;Mesothelial cells: 4.2;Neuroendocrine cells: 4.5;Podocytes: 7.2;Proximal tubule cells: 3.5;Schwann cells: 2.6;Thymocytes: 3.4" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in some" 6 "Colon Adenocarcinoma (TCGA): 8.8;Ovary Serous Cystadenocarcinoma (TCGA): 6.7;Rectum Adenocarcinoma (TCGA): 8.7;Stomach Adenocarcinoma (TCGA): 3.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "colorectal cancer: 7.5" "Adipose visceral - Mesothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA071809 Enhanced NA NA "Cluster 17: Intestine - Digestion" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 1 "HPA071809: " "unprognostic (4.03e-3)" "unprognostic (4.00e-2)" "unprognostic (4.47e-2)" "unprognostic (2.57e-2)" "unprognostic (3.78e-3)" "unprognostic (3.22e-3)" "unprognostic (4.14e-1)" "unprognostic (2.43e-1)" "unprognostic (1.66e-2)" "unprognostic (1.14e-1)" GAL3ST3 GAL3ST2 ENSG00000175229 "Galactose-3-O-sulfotransferase 3" Q96A11 11 66040765-66049161 "Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 9.1;thyroid gland: 12.4" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 3.9;Brain inhibitory neurons: 7.0;Cone photoreceptor cells: 4.1;Ependymal cells: 4.5;Epididymal efferent duct absorptive cells: 6.3;Epididymal efferent duct ciliated cells: 3.8;Oligodendrocyte progenitor cells: 8.0;Other brain neurons: 5.2;Pituitary stem cells: 6.8;Retinal amacrine cells: 4.2;Retinal horizontal cells: 4.0;Rod photoreceptor cells: 15.3;Smooth muscle cells: 3.7;Thyrotrophs: 4.5" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in some" 5 "Glioblastoma Multiforme (TCGA): 6.5;Ovary Serous Cystadenocarcinoma (TCGA): 8.5;Thyroid Carcinoma (TCGA): 13.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 3.5" "Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Skin - Keratinocyte (granular), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 79: Photoreceptor cells - Phototransduction" "unprognostic (3.58e-1)" "unprognostic (3.96e-2)" "unprognostic (2.01e-2)" "unprognostic (2.44e-2)" "potential prognostic unfavorable (1.36e-4)" "unprognostic (5.72e-2)" "unprognostic (2.71e-2)" GAL3ST4 FLJ12116 ENSG00000197093 "Galactose-3-O-sulfotransferase 4" Q96RP7 7 100159244-100168617 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 26.6" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 10.6;Esophageal basal cells: 10.6;Macrophages: 18.5;Microglia: 84.6;Oligodendrocyte progenitor cells: 24.3;Pituitary stem cells: 10.7;Salivary acinar cells: 10.7" "Cell type enriched" "Detected in many" 4 "central nervous system macrophage: 93.6" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 45.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "memory CD4 T-cell: 4.5;naive CD4 T-cell: 15.0;naive CD8 T-cell: 4.6;plasmacytoid DC: 4.7" "Group enriched" "Detected in many" 29 "dendritic cells: 4.7;T-cells: 15.0" "Cancer enhanced" "Detected in many" "skin cancer: 9.5" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Macrophages, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Keratinocyte (other), Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038137, HPA038138" Uncertain Approved Nucleoplasm,Cytosol NA NA 36000 "Cluster 30: Non-specific - DNA binding" "Cluster 58: Skin - Keratinization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 69: Skin cancer - ECM organization" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" Nucleoplasm Cytosol "HPA038137: , HPA038138: " "unprognostic (4.39e-3)" "unprognostic (1.25e-1)" "unprognostic (1.27e-1)" "unprognostic (2.24e-1)" "unprognostic (8.77e-3)" "unprognostic (6.72e-3)" "unprognostic (3.59e-2)" "unprognostic (2.40e-3)" "unprognostic (5.65e-2)" "unprognostic (3.41e-1)" "unprognostic (1.81e-1)" "unprognostic (3.76e-1)" "unprognostic (8.88e-2)" "unprognostic (5.66e-2)" "unprognostic (2.51e-2)" "unprognostic (1.84e-1)" "unprognostic (1.39e-3)" "unprognostic (1.66e-1)" "unprognostic (5.11e-2)" "potential prognostic unfavorable (8.13e-4)" "unprognostic (4.25e-2)" "unprognostic (1.39e-1)" "unprognostic (1.10e-1)" "unprognostic (1.91e-1)" "unprognostic (2.25e-1)" "unprognostic (2.67e-2)" "unprognostic (1.83e-1)" "unprognostic (2.87e-2)" "unprognostic (1.28e-1)" "unprognostic (2.50e-2)" "unprognostic (2.64e-1)" GALC ENSG00000054983 Galactosylceramidase P54803 14 87837820-87993665 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism, Sphingolipid metabolism" "Glycosidase, Hydrolase" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Kupffer cells: 150.7;Late spermatids: 121.8;Mast cells: 482.4;Neutrophils: 221.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022196 Approved "Intracellular and membrane" Enzyme NA NA 46000 "Cluster 25: Non-specific - Unknown function" "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 58: Mast cells - Allergic inflammatory responses" "CAB022196: " "unprognostic (3.49e-2)" "unprognostic (2.07e-1)" "unprognostic (3.96e-1)" "unprognostic (8.64e-3)" "unprognostic (2.03e-2)" "unprognostic (6.70e-3)" "unprognostic (4.77e-2)" "potential prognostic unfavorable (1.76e-4)" "unprognostic (1.16e-1)" "unprognostic (4.31e-2)" "potential prognostic favorable (5.11e-6)" "unprognostic (6.91e-2)" "unprognostic (1.31e-2)" "unprognostic (4.30e-1)" "unprognostic (3.35e-2)" "unprognostic (3.36e-2)" "unprognostic (2.02e-1)" "unprognostic (7.21e-3)" "unprognostic (2.92e-1)" "unprognostic (1.23e-1)" "potential prognostic unfavorable (9.42e-5)" "unprognostic (2.19e-2)" "unprognostic (1.75e-1)" "unprognostic (4.13e-2)" "unprognostic (3.65e-2)" "unprognostic (3.04e-2)" "unprognostic (1.12e-1)" "unprognostic (1.54e-2)" "unprognostic (1.91e-1)" "unprognostic (8.04e-2)" "unprognostic (1.43e-1)" GALE SDR1E1 ENSG00000117308 UDP-galactose-4-epimerase Q14376 1 23795599-23800781 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Galactose metabolism" Isomerase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "stomach 1: 115.5" "Cell type enhanced" "Detected in many" "Breast lactating cells: 195.6;Esophageal apical cells: 653.0;Extravillous trophoblasts: 146.0;Foveolar cells: 187.3;Goblet cells: 151.6;Hofbauer cells: 164.7;Syncytiotrophoblasts: 119.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070023 Approved "Golgi apparatus,Cytosol" NA NA 39000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 37: Non-specific - mRNA processing" "Cluster 84: Apical squamous epithelium - Cornification" 4 "Golgi apparatus, Cytosol" "HPA070023: " "unprognostic (2.18e-1)" "unprognostic (9.41e-3)" "unprognostic (2.44e-1)" "unprognostic (1.86e-1)" "unprognostic (3.62e-2)" "unprognostic (1.01e-1)" "potential prognostic unfavorable (3.79e-5)" "unprognostic (3.46e-2)" "unprognostic (1.60e-2)" "unprognostic (2.26e-1)" "unprognostic (6.39e-2)" "unprognostic (1.12e-1)" "unprognostic (1.49e-1)" "unprognostic (3.76e-3)" "unprognostic (1.07e-3)" "unprognostic (1.61e-1)" "unprognostic (3.31e-1)" "unprognostic (2.29e-3)" "unprognostic (6.68e-3)" "unprognostic (1.28e-1)" "unprognostic (1.19e-1)" "unprognostic (4.77e-3)" "unprognostic (4.16e-2)" "unprognostic (1.49e-1)" "unprognostic (6.35e-3)" "unprognostic (1.05e-1)" "unprognostic (5.40e-2)" "unprognostic (1.64e-1)" "unprognostic (3.54e-1)" "potential prognostic favorable (3.79e-4)" "unprognostic (8.36e-2)" GALK1 GALK ENSG00000108479 "Galactokinase 1" P51570 17 75751594-75765236 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Galactose metabolism" "Kinase, Transferase" "Cataract, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 98.5" "Cell type enhanced" "Detected in many" "Breast lactating cells: 105.0;Enterocytes: 124.4;Esophageal apical cells: 108.6;Esophageal suprabasal cells: 92.1;Extravillous trophoblasts: 156.3;Hepatocytes: 143.6" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 120.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Macrophages, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007094, HPA016960" Approved Approved "Golgi apparatus,Cytosol" NA NA 18000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 8: Non-specific - Secretory pathway" 6 Cytosol "Golgi apparatus" "HPA007094: , HPA016960: " "unprognostic (5.95e-3)" "unprognostic (2.42e-1)" "unprognostic (1.73e-2)" "unprognostic (2.47e-2)" "potential prognostic favorable (5.19e-4)" "unprognostic (1.54e-2)" "unprognostic (4.60e-2)" "unprognostic (3.35e-1)" "unprognostic (2.07e-1)" "unprognostic (1.28e-2)" "potential prognostic unfavorable (3.68e-4)" "unprognostic (8.75e-3)" "unprognostic (8.45e-2)" "unprognostic (1.65e-1)" "unprognostic (4.43e-2)" "unprognostic (2.96e-2)" "unprognostic (7.46e-3)" "unprognostic (3.28e-1)" "unprognostic (8.88e-2)" "unprognostic (1.71e-1)" "unprognostic (4.68e-2)" "unprognostic (9.10e-2)" "unprognostic (4.75e-1)" "unprognostic (4.65e-2)" "unprognostic (1.13e-1)" "unprognostic (1.56e-1)" "unprognostic (1.86e-1)" "unprognostic (1.29e-1)" "unprognostic (1.13e-1)" "unprognostic (7.39e-3)" "unprognostic (2.19e-2)" GALK2 GK2 ENSG00000156958 "Galactokinase 2" Q01415 15 49155656-49367869 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043564, HPA048267" Uncertain Approved Nucleoplasm,Cytosol NA NA 8000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 76: Non-specific - Metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 58: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" "Nucleoplasm, Cytosol" "HPA043564: , HPA048267: " "unprognostic (7.69e-2)" "unprognostic (1.22e-2)" "unprognostic (2.19e-2)" "unprognostic (1.11e-2)" "unprognostic (1.18e-1)" "unprognostic (3.26e-1)" "unprognostic (1.63e-1)" "unprognostic (3.20e-1)" "unprognostic (4.82e-2)" "unprognostic (2.56e-1)" "potential prognostic favorable (3.04e-8)" "unprognostic (1.17e-2)" "unprognostic (3.57e-2)" "unprognostic (1.06e-1)" "potential prognostic unfavorable (3.67e-4)" "unprognostic (8.68e-3)" "unprognostic (1.21e-1)" "unprognostic (3.80e-1)" "unprognostic (2.77e-2)" "unprognostic (5.19e-2)" "unprognostic (1.10e-1)" "unprognostic (2.04e-2)" "unprognostic (1.03e-1)" "unprognostic (2.02e-1)" "unprognostic (2.80e-2)" "unprognostic (7.04e-2)" "unprognostic (1.82e-1)" "unprognostic (3.47e-2)" "unprognostic (4.70e-2)" "unprognostic (1.18e-2)" "unprognostic (1.04e-1)" GALM ENSG00000143891 "Galactose mutarotase" Q96C23 2 38666081-38741237 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism" Isomerase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 89.6;kidney: 112.0" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 209.6;T-cells: 215.2" "Cell type enhanced" "Detected in all" "leukocyte: 78.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 68.5" "Group enriched" "Detected in all" 5 "granulocytes: 39.2;T-cells: 68.5" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Peritubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035472, HPA035473, HPA064835" Enhanced Uncertain Nucleoplasm NA NA 530000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 76: Non-specific - Metabolism" "Cluster 12: Non-specific - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 9: T-cells - Adaptive immunity: Regulation" 2 Nucleoplasm "HPA035472: , HPA035473: , HPA064835: " "unprognostic (1.40e-3)" "unprognostic (2.51e-1)" "unprognostic (1.50e-2)" "unprognostic (6.23e-2)" "unprognostic (3.35e-2)" "unprognostic (3.60e-3)" "unprognostic (4.41e-2)" "potential prognostic unfavorable (2.14e-4)" "unprognostic (8.78e-3)" "unprognostic (3.51e-2)" "potential prognostic favorable (1.19e-7)" "unprognostic (1.67e-2)" "unprognostic (4.88e-2)" "unprognostic (6.61e-3)" "unprognostic (2.84e-2)" "unprognostic (4.02e-3)" "unprognostic (4.10e-2)" "unprognostic (1.90e-1)" "unprognostic (2.00e-2)" "unprognostic (2.10e-1)" "unprognostic (4.04e-1)" "unprognostic (9.90e-3)" "potential prognostic favorable (6.88e-4)" "unprognostic (5.00e-2)" "unprognostic (2.00e-1)" "unprognostic (3.25e-2)" "unprognostic (2.63e-1)" "unprognostic (7.18e-2)" "unprognostic (8.59e-2)" "unprognostic (2.39e-1)" "unprognostic (1.47e-1)" GALNS "GalN6S, GALNAC6S, GAS" ENSG00000141012 "Galactosamine (N-acetyl)-6-sulfatase" P34059 16 88813734-88856970 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant, Dwarfism, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ependymal cells: 104.8;Epididymal efferent duct ciliated cells: 95.7;Late primary spermatocytes: 67.0;Respiratory ciliated cells: 85.2" "Cell type enhanced" "Detected in all" "ependymal cell: 122.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 11.3;granulocytes: 31.4;monocytes: 17.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026404, HPA042433, HPA074225" Supported Approved Cytosol "Intracellular and membrane" Enzyme NA NA 1300000 "Cluster 7: Non-specific - Innate immune response" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 5: Rhabdoid - Unknown function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 22 Cytosol "CAB026404: , HPA042433: , HPA074225: " "unprognostic (5.82e-3)" "unprognostic (4.34e-2)" "unprognostic (2.67e-1)" "unprognostic (2.68e-1)" "unprognostic (1.41e-1)" "unprognostic (2.43e-1)" "unprognostic (1.00e-1)" "unprognostic (2.70e-1)" "unprognostic (1.07e-2)" "unprognostic (1.77e-1)" "potential prognostic favorable (9.52e-4)" "unprognostic (8.36e-3)" "unprognostic (2.35e-1)" "potential prognostic unfavorable (3.32e-4)" "unprognostic (4.75e-3)" "unprognostic (2.41e-2)" "unprognostic (1.78e-1)" "unprognostic (6.62e-3)" "unprognostic (3.80e-1)" "unprognostic (1.33e-2)" "unprognostic (2.13e-1)" "unprognostic (2.02e-1)" "unprognostic (1.25e-2)" "unprognostic (1.76e-1)" "unprognostic (3.84e-1)" "unprognostic (7.03e-2)" "unprognostic (5.79e-2)" "unprognostic (6.66e-2)" "unprognostic (1.43e-1)" "unprognostic (2.02e-3)" "unprognostic (5.42e-2)" GALNT1 GalNAc-T1 ENSG00000141429 "Polypeptide N-acetylgalactosaminyltransferase 1" Q10472 18 35581117-35711834 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 645.6;Retinal pigment epithelial cells: 430.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012628 Uncertain "Intracellular and membrane" Enzyme NA NA 2400000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 24 "HPA012628: " "potential prognostic favorable (3.43e-5)" "unprognostic (1.28e-1)" "unprognostic (1.66e-1)" "unprognostic (1.92e-1)" "unprognostic (2.45e-3)" "unprognostic (6.32e-2)" "unprognostic (1.19e-1)" "unprognostic (1.13e-2)" "unprognostic (7.14e-2)" "unprognostic (2.11e-1)" "unprognostic (3.69e-2)" "unprognostic (3.29e-2)" "unprognostic (1.19e-1)" "unprognostic (1.53e-2)" "unprognostic (1.90e-2)" "unprognostic (7.90e-2)" "unprognostic (1.23e-1)" "unprognostic (1.09e-1)" "unprognostic (8.22e-2)" "unprognostic (1.55e-1)" "unprognostic (4.98e-2)" "unprognostic (1.45e-3)" "unprognostic (4.10e-1)" "unprognostic (5.70e-2)" "unprognostic (4.69e-2)" "unprognostic (1.73e-1)" "unprognostic (9.85e-3)" "unprognostic (6.02e-2)" "unprognostic (7.14e-2)" "unprognostic (5.30e-3)" "unprognostic (4.09e-1)" GALNT10 GalNAc-T10 ENSG00000164574 "Polypeptide N-acetylgalactosaminyltransferase 10" Q86SR1 5 154190730-154420984 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 51.6" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 380.9;Erythrocyte progenitors: 302.7;Megakaryocyte-Erythroid progenitors: 304.5;Pituicytes/FSCs: 783.1;Pituitary stem cells: 283.9" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 305.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pituitary gland - Undifferentiated cells (Pituitary gland), Spleen - B-cells (Spleen), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007525 Approved Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" "Intracellular and membrane" Enzyme NA NA 1000000 "Cluster 25: Non-specific - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 15: Kidney cancer - Membrane components" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 4 "Plasma membrane" "Nucleoplasm, Golgi apparatus" "HPA007525: " "unprognostic (4.05e-2)" "unprognostic (9.99e-2)" "unprognostic (2.27e-1)" "unprognostic (3.23e-2)" "unprognostic (2.04e-1)" "unprognostic (2.87e-1)" "unprognostic (1.59e-1)" "unprognostic (2.16e-1)" "unprognostic (5.16e-2)" "unprognostic (1.13e-1)" "unprognostic (2.63e-3)" "unprognostic (1.23e-2)" "unprognostic (2.20e-1)" "unprognostic (1.37e-3)" "unprognostic (2.50e-1)" "unprognostic (2.10e-1)" "unprognostic (1.08e-1)" "unprognostic (3.00e-1)" "unprognostic (1.77e-1)" "unprognostic (1.30e-3)" "unprognostic (1.64e-3)" "potential prognostic unfavorable (4.87e-4)" "unprognostic (1.22e-1)" "unprognostic (2.84e-1)" "unprognostic (1.23e-2)" "unprognostic (3.18e-1)" "unprognostic (1.09e-1)" "unprognostic (4.88e-3)" "unprognostic (8.14e-2)" "unprognostic (1.72e-2)" "unprognostic (1.27e-3)" GALNT11 GalNAc-T11 ENSG00000178234 "Polypeptide N-acetylgalactosaminyltransferase 11" Q8NCW6 7 152025674-152122340 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Notch signaling pathway" "Glycosyltransferase, Transferase" Heterotaxy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "choroid plexus: 799.6;kidney: 213.9" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 1027.2;Retinal pigment epithelial cells: 443.3" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 876.7" "Cancer enhanced" "Detected in all" "Kidney Renal Papillary Cell Carcinoma (TCGA): 271.2" "Region enriched" "Detected in all" 9 "choroid plexus: 878.7" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039330, HPA074862" Uncertain Approved "Endoplasmic reticulum,Golgi apparatus,Plasma membrane,Cytokinetic bridge,Primary cilium,Primary cilium tip,Basal body" Yes NA "Cluster 1: T-cells - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 2 "Endoplasmic reticulum, Golgi apparatus, Plasma membrane" "Cytokinetic bridge, Primary cilium, Primary cilium tip, Basal body" "HPA039330: , HPA074862: " "unprognostic (8.82e-2)" "unprognostic (1.66e-1)" "unprognostic (1.09e-1)" "unprognostic (1.01e-1)" "unprognostic (1.55e-1)" "unprognostic (3.39e-2)" "potential prognostic unfavorable (9.33e-4)" "unprognostic (1.95e-2)" "unprognostic (1.38e-1)" "unprognostic (9.63e-2)" "potential prognostic favorable (8.00e-8)" "unprognostic (3.65e-3)" "potential prognostic favorable (1.95e-7)" "unprognostic (1.69e-2)" "unprognostic (5.55e-2)" "unprognostic (1.04e-2)" "unprognostic (3.80e-1)" "unprognostic (2.14e-1)" "unprognostic (7.39e-3)" "unprognostic (1.35e-1)" "unprognostic (1.69e-1)" "unprognostic (3.90e-2)" "unprognostic (1.98e-2)" "unprognostic (2.14e-1)" "unprognostic (1.24e-1)" "unprognostic (9.58e-3)" "unprognostic (1.49e-1)" "unprognostic (4.43e-1)" "unprognostic (2.61e-1)" "unprognostic (7.90e-2)" "unprognostic (3.89e-2)" GALNT12 GalNAc-T12 ENSG00000119514 "Polypeptide N-acetylgalactosaminyltransferase 12" Q8IXK2 9 98807670-98850081 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 70.6;intestine: 52.4;stomach 1: 51.7" "Cell type enhanced" "Detected in many" "Colonocytes: 100.4;Epididymal principal cells: 71.0;Foveolar cells: 121.9;Gastric chief cells: 103.7;Goblet cells: 209.6;Mucous neck cells: 131.1;Parietal cells: 70.7" "Cell type enhanced" "Detected in many" "lower rhombic lip: 50.2;upper rhombic lip: 47.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 59.9" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Fibroblasts, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA048292, HPA071076" Enhanced Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA 47000 "Cluster 22: Eosinophils - Transcription" "Cluster 17: Intestine - Digestion" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 70: Intestinal goblet cells - Mucin production" 25 "Plasma membrane" "Nucleoplasm, Cell Junctions" "HPA048292: , HPA071076: " "unprognostic (4.18e-2)" "unprognostic (1.12e-2)" "unprognostic (1.87e-1)" "unprognostic (3.06e-1)" "unprognostic (1.08e-1)" "unprognostic (3.82e-1)" "unprognostic (2.74e-3)" "unprognostic (4.15e-3)" "unprognostic (6.07e-2)" "unprognostic (3.66e-2)" "potential prognostic favorable (4.08e-7)" "unprognostic (1.40e-1)" "unprognostic (3.52e-1)" "unprognostic (1.83e-2)" "unprognostic (2.65e-1)" "unprognostic (1.93e-1)" "unprognostic (1.57e-1)" "unprognostic (2.60e-2)" "unprognostic (1.55e-1)" "unprognostic (1.50e-1)" "unprognostic (3.49e-2)" "unprognostic (2.08e-2)" "unprognostic (1.99e-2)" "unprognostic (3.45e-1)" "unprognostic (2.09e-3)" "unprognostic (2.23e-1)" "unprognostic (1.97e-2)" "unprognostic (1.45e-1)" "unprognostic (2.81e-2)" "unprognostic (1.33e-1)" GALNT13 "GalNAc-T13, KIAA1918" ENSG00000144278 "Polypeptide N-acetylgalactosaminyltransferase 13" Q8IUC8 2 153871922-154453979 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.8;retina: 9.2" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 744.6;Bergmann glia: 1857.6;Brain excitatory neurons: 779.9;Brain inhibitory neurons: 616.7;Cone photoreceptor cells: 1258.6;Corticotrophs: 605.1;Endometrial stromal cells: 448.0;Oligodendrocyte progenitor cells: 1434.3;Oligodendrocytes: 742.8;Other brain neurons: 580.1;Retinal horizontal cells: 1540.6" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in some" 5 "Glioblastoma Multiforme (TCGA): 10.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 27.4" "Lung - Alveolar cells type 1, Pituitary gland - Corticotropes, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060775 Approved NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 25: Non-specific - Transcription" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" "HPA060775: " "unprognostic (1.35e-1)" "unprognostic (1.04e-1)" "unprognostic (3.48e-1)" "unprognostic (1.88e-2)" "potential prognostic favorable (2.86e-5)" "unprognostic (1.70e-2)" "unprognostic (2.46e-2)" "unprognostic (1.40e-1)" "unprognostic (7.82e-2)" "unprognostic (1.47e-1)" GALNT14 "FLJ12691, GalNac-T10, GalNac-T14" ENSG00000158089 "Polypeptide N-acetylgalactosaminyltransferase 14" Q96FL9 2 30910467-31155202 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 38.6" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 132.2;Distal convoluted tubule cells: 200.4;Esophageal apical cells: 337.0;Lactotrophs: 310.3;Loop of henle epithelial cells: 334.2;Neutrophil progenitors: 120.6;Neutrophils: 248.7;Ocular epithelial cells: 151.6;Proximal tubule cells: 656.4;Renal connecting tubule cells: 182.0" "Cell type enhanced" "Detected in all" "cerebellar inhibitory: 361.5;midbrain-derived inhibitory: 754.6" "Group enriched" "Detected in many" 7 "Kidney Renal Clear Cell Carcinoma (TCGA): 117.4;Kidney Renal Papillary Cell Carcinoma (TCGA): 97.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 8 "neutrophil: 8.5" "Lineage enriched" "Detected in many" 8 "granulocytes: 8.5" "Cancer enriched" "Detected in many" 5 "Kidney cancer: 123.7" "Adrenal gland - Adrenal medulla cells, Pituitary gland - Lactotropes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA030138 Approved "Nucleoplasm,Golgi apparatus" NA NA 9200 "Cluster 20: Non-specific - DNA binding" "Cluster 72: Kidney - Transmembrane transport" "Cluster 38: Sub-cortical - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 88: Proximal tubular cells - Transmembrane transport" 1 "Golgi apparatus" Nucleoplasm "HPA030138: " "unprognostic (1.92e-2)" "unprognostic (7.90e-2)" "unprognostic (7.01e-2)" "unprognostic (1.62e-1)" "unprognostic (2.05e-3)" "potential prognostic favorable (1.07e-6)" "unprognostic (4.66e-3)" "unprognostic (2.00e-1)" "validated prognostic favorable (5.97e-10)" "validated prognostic favorable (2.96e-4)" "unprognostic (9.96e-2)" "potential prognostic unfavorable (3.46e-4)" "unprognostic (3.03e-3)" "unprognostic (6.76e-2)" "unprognostic (2.65e-1)" "unprognostic (7.67e-2)" "unprognostic (2.24e-1)" "unprognostic (1.62e-3)" "unprognostic (2.05e-3)" "unprognostic (2.07e-1)" "unprognostic (6.02e-2)" "unprognostic (1.12e-2)" "unprognostic (4.70e-2)" "unprognostic (2.58e-1)" "unprognostic (1.72e-2)" GALNT15 "GALNT7, GALNTL2, pp-GalNAc-T15" ENSG00000131386 "Polypeptide N-acetylgalactosaminyltransferase 15" Q8N3T1 3 16174680-16231992 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 132.1" "Cell type enhanced" "Detected in many" "Astrocytes: 69.8;Fibro-adipogenic progenitors: 101.7;Fibroblasts: 300.9;Late primary spermatocytes: 75.7;Lymphatic endothelial cells: 69.7;Medullary thymic epithelial cells: 165.6;Müller glia: 86.5;Myosatellite cells: 112.1;Oligodendrocytes: 71.5;Salivary myoepithelial cells: 106.6;Vascular endothelial cells: 135.8" "Group enriched" "Detected in all" 6 "astrocyte: 165.9;endothelial cell: 311.0;oligodendrocyte: 121.3" "Group enriched" "Detected in all" 6 "Glioblastoma Multiforme (TCGA): 49.2;Kidney Renal Clear Cell Carcinoma (TCGA): 13.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Skin - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA017076 Uncertain Approved "Golgi apparatus,Cytosol" NA NA 40000 "Cluster 41: Basophils - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 22: Non-specific - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 13 "Golgi apparatus" Cytosol "HPA017076: " "unprognostic (1.03e-1)" "unprognostic (2.77e-1)" "unprognostic (5.56e-3)" "unprognostic (5.96e-2)" "unprognostic (3.33e-1)" "unprognostic (3.59e-1)" "unprognostic (1.94e-1)" "unprognostic (2.96e-1)" "unprognostic (5.36e-2)" "potential prognostic favorable (3.32e-8)" "unprognostic (1.99e-2)" "unprognostic (3.37e-1)" "unprognostic (1.07e-2)" "unprognostic (2.64e-1)" "unprognostic (5.93e-2)" "unprognostic (2.87e-1)" "unprognostic (2.11e-2)" "unprognostic (6.55e-2)" "unprognostic (5.42e-2)" "unprognostic (1.77e-1)" "unprognostic (1.44e-1)" "unprognostic (1.60e-1)" "unprognostic (8.59e-2)" "unprognostic (1.14e-1)" "potential prognostic unfavorable (6.01e-4)" "unprognostic (2.20e-1)" "unprognostic (1.95e-1)" "unprognostic (1.13e-2)" GALNT16 "GalNAc-T16, GALNTL1, KIAA1130" ENSG00000100626 "Polypeptide N-acetylgalactosaminyltransferase 16" Q8N428 14 69259277-69357033 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.4;heart muscle: 46.5" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 31.9;Brain excitatory neurons: 39.3;Brain inhibitory neurons: 41.0;Cardiomyocytes: 82.9;Early spermatids: 46.0;Ependymal cells: 52.7;Fibro-adipogenic progenitors: 56.5;Fibroblasts: 26.7;Late spermatids: 40.6;Other brain neurons: 52.6;Pericytes: 30.0;Vascular smooth muscle cells: 32.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 11.2;Sarcoma: 8.5" "Adipose subcutaneous - Adipose progenitor cells, Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059136, HPA075325" Approved Approved Vesicles,Cytosol NA NA 27000 "Cluster 35: Non-specific - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 108: Fibroblasts - ECM organization" 1 "Vesicles, Cytosol" "HPA059136: , HPA075325: " "unprognostic (7.30e-2)" "unprognostic (3.89e-2)" "unprognostic (1.43e-3)" "unprognostic (5.87e-2)" "unprognostic (4.35e-2)" "unprognostic (1.76e-1)" "unprognostic (1.45e-3)" "unprognostic (3.09e-2)" "unprognostic (2.39e-3)" "potential prognostic favorable (5.85e-6)" "unprognostic (2.50e-2)" "unprognostic (5.22e-2)" "potential prognostic favorable (6.08e-5)" "unprognostic (1.13e-1)" "unprognostic (1.69e-2)" "unprognostic (9.01e-2)" "unprognostic (3.07e-3)" "unprognostic (5.09e-2)" "unprognostic (7.51e-2)" "unprognostic (6.32e-3)" GALNT17 "GalNAc-T17, GalNAc-T19, GalNAc-T5L, GALNTL3, ppGalNAc-T17, WBSCR17" ENSG00000185274 "Polypeptide N-acetylgalactosaminyltransferase 17" Q6IS24 7 71132144-71713600 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 65.0;choroid plexus: 59.6" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 630.4;Cardiomyocytes: 729.8;Choroid plexus epithelial cells: 1724.1;Gonadotrophs: 620.5;Lactotrophs: 759.3;Prostatic glandular cells: 629.8;Renal collecting duct intercalated cells: 1060.3;Retinal ganglion cells: 417.2;Somatotrophs: 730.0;Thymic myoid cells: 596.9;Thyrotrophs: 1224.2" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 8 "Kidney Chromophobe (TCGA): 130.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 9.7;testis cancer: 13.0" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Cardiomyocytes, Kidney - Intercalated cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013624, HPA047986" Approved Approved "Nucleoplasm,Nucleoli,Nuclear bodies,Golgi apparatus" NA NA "Cluster 65: Brain - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 101: Choroid plexus epithelial cells - Ion transport" "Nucleoplasm, Golgi apparatus" "Nucleoli, Nuclear bodies" "HPA013624: , HPA047986: " "unprognostic (4.09e-2)" "unprognostic (1.80e-2)" "unprognostic (1.69e-1)" "unprognostic (3.42e-2)" "unprognostic (1.28e-1)" "unprognostic (2.80e-1)" "unprognostic (4.44e-1)" "potential prognostic unfavorable (2.89e-4)" "unprognostic (2.88e-2)" "unprognostic (7.75e-2)" "unprognostic (9.70e-3)" "unprognostic (7.54e-2)" "unprognostic (2.64e-3)" "unprognostic (4.26e-1)" "unprognostic (2.80e-1)" "unprognostic (4.14e-2)" "unprognostic (3.76e-1)" "unprognostic (8.06e-3)" "unprognostic (1.06e-1)" "unprognostic (2.13e-2)" GALNT18 "GalNAc-T18, GALNT15, GALNTL4, MGC71806" ENSG00000110328 "Polypeptide N-acetylgalactosaminyltransferase 18" Q6P9A2 11 11270877-11622005 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 360.4;Brain excitatory neurons: 280.9;Choroid plexus epithelial cells: 273.6;Loop of henle epithelial cells: 369.0;Lymphatic endothelial cells: 426.3;Proximal tubule cells: 443.8;Sertoli cells: 408.3;Vascular endothelial cells: 466.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Endothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Endothelial cells, Stomach - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012955, HPA070681" Approved Approved "Golgi apparatus,Vesicles,Cytosol" NA NA 130000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 29: Forebrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 27 "Golgi apparatus" "Vesicles, Cytosol" "HPA012955: , HPA070681: " "unprognostic (5.75e-2)" "unprognostic (4.04e-1)" "unprognostic (1.72e-1)" "unprognostic (1.12e-1)" "unprognostic (4.41e-2)" "unprognostic (8.94e-2)" "unprognostic (2.74e-1)" "unprognostic (1.45e-1)" "unprognostic (2.49e-1)" "potential prognostic favorable (3.08e-6)" "unprognostic (3.12e-3)" "unprognostic (1.04e-1)" "unprognostic (1.08e-2)" "unprognostic (1.32e-2)" "unprognostic (1.82e-2)" "unprognostic (2.51e-1)" "unprognostic (9.94e-2)" "unprognostic (2.17e-1)" "unprognostic (5.97e-2)" "unprognostic (2.18e-1)" "unprognostic (3.27e-1)" "unprognostic (4.42e-1)" "unprognostic (1.91e-1)" "unprognostic (2.22e-1)" "unprognostic (1.90e-1)" "unprognostic (1.95e-2)" "unprognostic (1.90e-1)" "unprognostic (1.30e-1)" "unprognostic (3.37e-3)" GALNT2 GalNAc-T2 ENSG00000143641 "Polypeptide N-acetylgalactosaminyltransferase 2" Q10471 1 230057990-230282122 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglia: 478.9;Pancreatic acinar cells: 622.5" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 619.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Macrophages, Breast - Adipocytes (Breast), Kidney - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011222 Supported Supported "Golgi apparatus" "Intracellular and membrane" Enzyme NA NA 11000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 12: Non-specific - Vasculature" "Cluster 69: Skin cancer - ECM organization" "Cluster 103: Non-specific - Basic cellular processes" 31 "Golgi apparatus" "HPA011222: " "unprognostic (2.99e-1)" "unprognostic (2.10e-1)" "unprognostic (1.81e-2)" "potential prognostic unfavorable (4.59e-5)" "unprognostic (2.03e-1)" "unprognostic (2.51e-1)" "unprognostic (9.63e-2)" "unprognostic (9.50e-2)" "unprognostic (6.91e-2)" "unprognostic (2.20e-1)" "validated prognostic unfavorable (3.50e-4)" "validated prognostic unfavorable (3.41e-4)" "potential prognostic unfavorable (3.18e-4)" "unprognostic (7.62e-2)" "unprognostic (1.68e-2)" "potential prognostic unfavorable (1.89e-6)" "unprognostic (6.08e-3)" "unprognostic (1.86e-3)" "unprognostic (3.32e-1)" "unprognostic (1.64e-1)" "unprognostic (5.92e-2)" "unprognostic (2.08e-2)" "unprognostic (1.97e-2)" "unprognostic (2.39e-1)" "potential prognostic unfavorable (4.81e-5)" "unprognostic (1.69e-1)" "unprognostic (7.42e-2)" "unprognostic (5.00e-3)" "unprognostic (1.52e-1)" "unprognostic (1.33e-1)" "unprognostic (2.30e-1)" GALNT3 "GalNAc-T3, HFTC, HHS" ENSG00000115339 "Polypeptide N-acetylgalactosaminyltransferase 3" Q14435 2 165747588-165794659 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 73.0" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 269.8;Goblet cells: 249.3;Late primary spermatocytes: 248.6;Ocular epithelial cells: 298.8" "Cell type enhanced" "Detected in all" "ependymal cell: 118.3;leukocyte: 72.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 50.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose visceral - T-cells, Lung - Alveolar cells type 2, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA007613 Enhanced Supported "Golgi apparatus" NA NA 34000 "Cluster 32: Basophils - Transcription" "Cluster 60: Stomach - Digestion" "Cluster 39: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 2 "Golgi apparatus" "HPA007613: " "unprognostic (8.80e-2)" "unprognostic (1.62e-1)" "unprognostic (2.75e-1)" "potential prognostic unfavorable (7.09e-4)" "unprognostic (2.23e-2)" "unprognostic (6.02e-2)" "unprognostic (7.73e-2)" "unprognostic (1.69e-3)" "potential prognostic unfavorable (6.95e-4)" "unprognostic (2.78e-2)" "unprognostic (1.67e-1)" "unprognostic (1.50e-1)" "unprognostic (1.42e-2)" "unprognostic (2.61e-3)" "unprognostic (2.18e-1)" "potential prognostic unfavorable (6.78e-4)" "unprognostic (1.43e-1)" "unprognostic (2.72e-1)" "unprognostic (8.26e-2)" "unprognostic (2.26e-2)" "unprognostic (1.88e-1)" "unprognostic (3.58e-3)" "unprognostic (3.95e-1)" "unprognostic (1.29e-1)" "unprognostic (5.35e-3)" "unprognostic (7.06e-2)" "unprognostic (1.83e-1)" "unprognostic (4.80e-2)" "unprognostic (2.40e-1)" "unprognostic (8.27e-2)" "unprognostic (1.71e-1)" GALNT4 GalNAc-T4 ENSG00000257594 "Polypeptide N-acetylgalactosaminyltransferase 4" Q8N4A0 12 89519412-89524796 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 29.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076116 Approved "Golgi apparatus" NA NA 640000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 17: Intestine - Digestion" "Cluster 39: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" 3 "Golgi apparatus" "HPA076116: " "unprognostic (7.13e-2)" "unprognostic (1.53e-1)" "potential prognostic favorable (3.92e-4)" "unprognostic (3.64e-2)" "unprognostic (4.36e-2)" "unprognostic (2.17e-1)" "unprognostic (7.78e-2)" "unprognostic (3.09e-2)" "unprognostic (1.04e-1)" "potential prognostic favorable (4.58e-8)" "unprognostic (2.92e-3)" "unprognostic (1.92e-2)" "unprognostic (3.80e-2)" "unprognostic (1.28e-1)" "unprognostic (3.12e-3)" "unprognostic (2.78e-1)" "unprognostic (1.42e-1)" "unprognostic (5.63e-3)" "unprognostic (1.54e-1)" "unprognostic (1.04e-1)" "unprognostic (2.26e-2)" "unprognostic (1.01e-2)" "unprognostic (3.39e-2)" "unprognostic (2.51e-2)" "unprognostic (1.20e-2)" "unprognostic (3.62e-1)" "unprognostic (2.49e-1)" "unprognostic (8.46e-2)" "unprognostic (2.44e-1)" "unprognostic (4.15e-3)" GALNT5 GalNAc-T5 ENSG00000136542 "Polypeptide N-acetylgalactosaminyltransferase 5" Q7Z7M9 2 157257705-157318491 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 12.7;lung: 9.6;stomach 1: 12.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 220.1;Choroid plexus epithelial cells: 91.7;Colonocytes: 84.8;Conjunctival goblet cells: 76.7;Endometrial secretory cells: 87.5;Esophageal apical cells: 92.6;Foveolar cells: 146.9;Goblet cells: 257.1;Lacrimal acinar cells: 79.7;Ocular epithelial cells: 104.7;Respiratory basal cells: 66.3;Respiratory deuterosomal cells: 81.9;Salivary basal cells: 102.4" "Group enriched" "Detected in some" 11 "choroid plexus epithelial cell: 69.9;upper rhombic lip: 75.4" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 7 "cerebellum: 8.9;choroid plexus: 11.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 40.6" "Adipose subcutaneous - Adipose progenitor cells, Breast - Breast myoepithelial cells, Colon - Colon enterocytes, Lung - Alveolar cells type 1, Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Fibroblasts, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA008963, HPA009035" Approved Approved "Nucleoli,Golgi apparatus,Vesicles,Cytosol" NA NA 1100000 "Cluster 17: Intestine - Digestion" "Cluster 5: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 70: Intestinal goblet cells - Mucin production" 9 "Golgi apparatus, Cytosol" "Nucleoli, Vesicles" "HPA008963: , HPA009035: " "unprognostic (2.07e-1)" "unprognostic (2.91e-2)" "unprognostic (1.02e-1)" "unprognostic (6.67e-2)" "unprognostic (1.47e-1)" "unprognostic (4.11e-2)" "unprognostic (2.42e-3)" "unprognostic (3.60e-2)" "unprognostic (5.73e-2)" "unprognostic (9.02e-3)" "unprognostic (1.85e-1)" "unprognostic (8.10e-3)" "unprognostic (1.46e-1)" "unprognostic (8.57e-2)" "potential prognostic unfavorable (1.64e-5)" "unprognostic (9.69e-3)" "unprognostic (1.87e-2)" "unprognostic (1.38e-2)" "unprognostic (1.58e-2)" "unprognostic (3.42e-1)" "unprognostic (7.14e-2)" GALNT6 GalNAc-T6 ENSG00000139629 "Polypeptide N-acetylgalactosaminyltransferase 6" Q8NCL4 12 51351247-51392867 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 30.2;stomach 1: 59.0" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 79.1;Enterocytes: 75.9;Epididymal principal cells: 86.6;Extravillous trophoblasts: 74.9;Foveolar cells: 327.6;Lacrimal acinar cells: 113.2;Mast cells: 177.9;Respiratory deuterosomal cells: 103.7;Respiratory secretory cells: 106.8;Salivary acinar cells: 94.9" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 26.5;leukocyte: 30.6;oligodendrocyte: 70.4" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 79.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 29.2" "Group enriched" "Detected in all" 4 "granulocytes: 29.2;monocytes: 9.8;NK-cells: 15.7" "Cancer enhanced" "Detected in many" "breast cancer: 56.1" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Breast glandular cells, Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011762, HPA017086" Enhanced Approved "Nucleoplasm,Golgi apparatus" NA NA 2700000 "Cluster 45: Eosinophils - Unknown function" "Cluster 60: Stomach - Digestion" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 68: Foveolar cells - Mucosal defense" 11 "Nucleoplasm, Golgi apparatus" "HPA011762: , HPA017086: " "unprognostic (1.35e-1)" "unprognostic (8.18e-2)" "unprognostic (2.11e-1)" "unprognostic (8.03e-2)" "unprognostic (1.76e-1)" "unprognostic (3.60e-1)" "unprognostic (1.48e-2)" "unprognostic (2.96e-1)" "unprognostic (7.97e-2)" "unprognostic (1.86e-1)" "unprognostic (1.79e-1)" "unprognostic (2.43e-1)" "unprognostic (2.70e-1)" "unprognostic (7.14e-2)" "unprognostic (2.38e-1)" "potential prognostic unfavorable (8.42e-4)" "unprognostic (1.90e-1)" "unprognostic (3.17e-1)" "potential prognostic favorable (4.66e-4)" "unprognostic (3.62e-2)" "unprognostic (1.80e-2)" "unprognostic (1.84e-3)" "unprognostic (1.03e-1)" "unprognostic (5.46e-2)" "unprognostic (6.89e-2)" "unprognostic (1.32e-2)" "unprognostic (1.31e-2)" "unprognostic (3.44e-1)" "unprognostic (1.07e-2)" "unprognostic (1.57e-2)" GALNT7 GALNAC-T7 ENSG00000109586 "Polypeptide N-acetylgalactosaminyltransferase 7" Q86SF2 4 173168811-173323967 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "stomach 1: 61.9" "Cell type enhanced" "Detected in many" "Neutrophils: 409.6;Prostatic glandular cells: 912.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064243, HPA065317" Enhanced Approved "Nucleoplasm,Golgi apparatus" NA NA 5100000 "Cluster 35: Neutrophils - Protein binding" "Cluster 17: Intestine - Digestion" "Cluster 25: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 5 "Golgi apparatus" Nucleoplasm "HPA064243: , HPA065317: " "unprognostic (1.93e-1)" "unprognostic (9.39e-2)" "unprognostic (2.20e-1)" "unprognostic (1.94e-1)" "potential prognostic favorable (1.55e-4)" "unprognostic (3.21e-1)" "unprognostic (2.46e-1)" "unprognostic (3.79e-2)" "unprognostic (6.30e-2)" "unprognostic (6.03e-2)" "unprognostic (1.74e-2)" "unprognostic (8.02e-3)" "unprognostic (1.74e-2)" "unprognostic (1.70e-2)" "unprognostic (2.91e-2)" "unprognostic (4.21e-2)" "unprognostic (7.87e-2)" "unprognostic (2.02e-1)" "unprognostic (1.78e-1)" "unprognostic (1.08e-2)" "unprognostic (1.02e-1)" "unprognostic (2.89e-3)" "unprognostic (2.12e-1)" "unprognostic (1.37e-1)" "unprognostic (2.19e-1)" "unprognostic (1.11e-2)" "unprognostic (1.33e-2)" "unprognostic (2.09e-1)" "unprognostic (1.94e-1)" "unprognostic (2.05e-2)" "unprognostic (1.23e-2)" GALNT8 GALNAC-T8 ENSG00000130035 "Polypeptide N-acetylgalactosaminyltransferase 8" Q9NY28 12 4720400-4851927 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 29.3;testis: 10.4" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 31.9;Corticotrophs: 31.9;Early spermatids: 79.3;Ependymal cells: 93.7;Goblet cells: 223.1;Late spermatids: 141.1;Oligodendrocyte progenitor cells: 45.7" "Cell type enhanced" "Detected in all" "ependymal cell: 111.2" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 14.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "thyroid cancer: 2.6" "Adrenal gland - Adrenal medulla cells, Pancreas - Alpha cells, Skeletal muscle - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "HPA012638, HPA073461" Supported Approved "Golgi apparatus,Vesicles" NA No "Cluster 77: Intestine - Digestion" "Cluster 11: White matter - Signal transduction" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 70: Intestinal goblet cells - Mucin production" 1 "Golgi apparatus" Vesicles "HPA012638: , HPA073461: " "unprognostic (7.14e-2)" "unprognostic (1.77e-2)" "unprognostic (3.49e-1)" "unprognostic (1.13e-3)" "unprognostic (2.12e-1)" "unprognostic (1.29e-1)" "unprognostic (1.58e-1)" "unprognostic (1.43e-1)" "unprognostic (2.01e-1)" "unprognostic (2.49e-1)" "unprognostic (1.35e-1)" "unprognostic (2.74e-3)" "unprognostic (2.16e-3)" "unprognostic (2.25e-1)" "unprognostic (6.69e-2)" "unprognostic (6.38e-2)" "unprognostic (2.26e-2)" GALNT9 GALNAC-T9 ENSG00000182870 "Polypeptide N-acetylgalactosaminyltransferase 9" Q9HCQ5 12 132196372-132329589 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "brain: 127.7" "Cell type enhanced" "Detected in some" "Bergmann glia: 8.2;Brain excitatory neurons: 60.2;Brain inhibitory neurons: 11.8;Distal convoluted tubule cells: 7.7;Loop of henle epithelial cells: 30.0;Other brain neurons: 17.0;Proximal tubule cells: 6.0;Renal collecting duct intercalated cells: 4.8;Renal collecting duct principal cells: 8.3;Renal connecting tubule cells: 6.4" "Cell type enhanced" "Detected in all" "upper rhombic lip: 106.4" "Cancer enhanced" "Detected in some" "Kidney Renal Clear Cell Carcinoma (TCGA): 7.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney cancer: 5.1" "Adipose visceral - Mesothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075016 Approved Vesicles NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 37: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 2: Cerebellar granular cells - Neuronal signaling" Vesicles "HPA075016: " "unprognostic (8.21e-2)" "unprognostic (1.83e-2)" "unprognostic (1.40e-3)" "unprognostic (1.01e-2)" "unprognostic (2.27e-2)" "unprognostic (2.34e-2)" "unprognostic (4.36e-2)" "unprognostic (1.37e-1)" GALNTL5 "GalNAc-T5L, GALNT15" ENSG00000106648 "Polypeptide N-acetylgalactosaminyltransferase like 5" Q7Z4T8 7 151956379-152019929 "Disease related genes, Predicted membrane proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 10.5" "Cell type enhanced" "Detected in some" "Early spermatids: 659.2;Late primary spermatocytes: 213.5;Late spermatids: 876.2" "Cell type enhanced" "Detected in some" "upper-layer intratelencephalic: 3.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA011140 Enhanced NA NA "Cluster 67: Testis - Mixed function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 1 "HPA011140: " GALNTL6 "GalNAc-T6L, GALNT17" ENSG00000174473 "Polypeptide N-acetylgalactosaminyltransferase like 6" Q49A17 4 171812254-173041559 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 3.9;lymphoid tissue: 2.4;testis: 2.3" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 1114.0;Brain inhibitory neurons: 2134.9;Melanocytes: 388.9;Other brain neurons: 934.1;Retinal ganglion cells: 1008.2" "Cell type enhanced" "Detected in all" "mammillary body: 12327.0;midbrain-derived inhibitory: 8295.9" "Cancer enriched" "Detected in some" 4 "Kidney Chromophobe (TCGA): 5.6" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.6" "Lineage enriched" "Detected in single" 8 "B-cells: 1.6" "Cancer enhanced" "Detected in single" "Neuroblastoma: 2.6" "Minor Salivary Gland - Minor salivary glandular cells, Skin - Melanocytes, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031019 Uncertain NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 109: Neurons - Neuronal signaling" "HPA031019: " "unprognostic (2.63e-2)" "unprognostic (9.73e-2)" "unprognostic (1.55e-3)" "unprognostic (5.17e-2)" "unprognostic (1.70e-1)" "unprognostic (1.15e-1)" "unprognostic (2.38e-2)" GALP ENSG00000197487 "Galanin like peptide" Q9UBC7 19 56176008-56185775 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Hormone, Neuropeptide" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Endometrial glandular cells: 1.0;Parietal cells: 1.8;Retinal pigment epithelial cells: 4.3;Undifferentiated spermatogonia: 1.7" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Uterine Corpus Endometrial Carcinoma (TCGA): 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA053938 Uncertain "Secreted in brain" Hormone NA NA "Cluster 1: Neuronal - Visual perception" "Cluster 51: Secretory epithelial cells - Mixed function" 2 "HPA053938: " "unprognostic (3.11e-1)" GALR1 "GALNR, GALNR1" ENSG00000166573 "Galanin receptor 1" P47211 18 77249848-77277900 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 1.4;pituitary gland: 1.3" "Cell type enriched" "Detected in some" 6 "Pituitary stem cells: 577.6" "Cell type enriched" "Detected in many" 6 "oligodendrocyte precursor cell: 99.0" "Group enriched" "Detected in some" 8 "Glioblastoma Multiforme (TCGA): 1.7;Kidney Chromophobe (TCGA): 2.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Neuroblastoma: 1.4" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Testis - Early spermatids, Testis - Late spermatids" "Region enhanced" "Detected in some" "hypothalamus: 5.2" "Low region specificity" "Detected in all" HPA074584 Supported "Plasma membrane" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 66: Non-specific - Mitochondria" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" "Plasma membrane" "HPA074584: " "unprognostic (2.32e-2)" "unprognostic (3.23e-2)" "unprognostic (1.65e-1)" GALR2 GALNR2 ENSG00000182687 "Galanin receptor 2" O43603 17 76074781-76077537 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 7.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "thyroid cancer: 3.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA044513 Uncertain NA NA "Cluster 77: Intestine - Digestion" "Cluster 1: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "HPA044513: " "unprognostic (7.94e-3)" GALR3 ENSG00000128310 "Galanin receptor 3" O60755 22 37823382-37825485 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Endometrial glandular cells: 1.4;Epicardial cells: 2.3;Late primary spermatocytes: 1.1;Late spermatids: 3.2;Megakaryocyte-Erythroid progenitors: 1.1;Other brain neurons: 1.9" "Low cell type specificity" "Detected in some" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 70: DU4475 - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" GALT ENSG00000213930 "Galactose-1-phosphate uridylyltransferase" P07902 9 34638133-34651035 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Galactose metabolism" "Nucleotidyltransferase, Transferase" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 44.3" "Cell type enhanced" "Detected in many" "Astrocytes: 28.7;Bergmann glia: 28.6;Brain excitatory neurons: 22.5;Brain inhibitory neurons: 24.6;Ependymal cells: 15.6;Microglia: 15.3;Oligodendrocyte progenitor cells: 16.6;Oligodendrocytes: 15.4;Other brain neurons: 27.8;Retinal amacrine cells: 17.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004868, HPA005729" Enhanced Approved Cytosol NA NA 240000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 45: Non-specific - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" 13 Cytosol "HPA004868: , HPA005729: " "unprognostic (3.71e-2)" "unprognostic (1.32e-1)" "unprognostic (1.42e-1)" "unprognostic (2.29e-3)" "unprognostic (1.01e-1)" "unprognostic (9.68e-3)" "unprognostic (4.28e-2)" "unprognostic (2.22e-2)" "unprognostic (2.78e-2)" "unprognostic (2.24e-1)" "potential prognostic favorable (1.92e-7)" "unprognostic (2.28e-2)" "unprognostic (5.34e-2)" "unprognostic (4.30e-1)" "unprognostic (5.52e-2)" "unprognostic (4.12e-1)" "unprognostic (2.50e-1)" "unprognostic (1.81e-2)" "unprognostic (1.90e-1)" "unprognostic (3.15e-1)" "unprognostic (6.44e-2)" "unprognostic (3.22e-2)" "unprognostic (1.80e-2)" "unprognostic (1.73e-1)" "unprognostic (6.44e-2)" "unprognostic (2.52e-3)" "unprognostic (3.30e-2)" "unprognostic (7.49e-3)" "unprognostic (3.65e-1)" "unprognostic (1.87e-1)" "unprognostic (1.31e-1)" GAMT "PIG2, TP53I2" ENSG00000130005 "Guanidinoacetate N-methyltransferase" Q14353 19 1397026-1401570 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 610.2;skeletal muscle: 1157.4;tongue: 435.1" "Group enriched" "Detected in many" 4 "Epididymal efferent duct absorptive cells: 486.9;Epididymal principal cells: 1113.6;Hepatocytes: 806.0;Thymic myoid cells: 652.6" "Cell type enhanced" "Detected in all" "oligodendrocyte: 63.8" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 355.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Keratinocyte (other), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051806 Approved NA NA 200000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 11: White matter - Signal transduction" "Cluster 35: RS4;11 - Unknown function" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 8 "HPA051806: " "unprognostic (2.65e-1)" "unprognostic (2.08e-1)" "unprognostic (1.10e-1)" "unprognostic (3.50e-2)" "unprognostic (4.24e-2)" "unprognostic (5.80e-2)" "unprognostic (1.38e-2)" "potential prognostic unfavorable (4.89e-4)" "unprognostic (1.47e-1)" "unprognostic (1.96e-2)" "potential prognostic favorable (3.69e-5)" "unprognostic (3.71e-2)" "unprognostic (2.83e-3)" "unprognostic (1.71e-2)" "unprognostic (5.04e-3)" "unprognostic (1.16e-1)" "unprognostic (3.80e-3)" "unprognostic (6.87e-3)" "unprognostic (5.23e-2)" "unprognostic (4.44e-1)" "unprognostic (2.05e-1)" "unprognostic (1.06e-1)" "unprognostic (7.11e-3)" "unprognostic (2.15e-2)" "unprognostic (1.70e-1)" "unprognostic (2.39e-1)" "unprognostic (9.69e-2)" "unprognostic (1.95e-3)" "unprognostic (1.53e-1)" "unprognostic (2.56e-2)" "unprognostic (7.20e-2)" GAN "GAN1, GIG, KLHL16" ENSG00000261609 Gigaxonin Q9H2C0 16 81314944-81390809 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 23.5" "Cell type enhanced" "Detected in many" "Astrocytes: 235.0;Basal keratinocytes: 247.7;Bergmann glia: 245.4;Suprabasal keratinocytes: 294.8;Urothelial cells: 627.0" "Cell type enhanced" "Detected in all" "astrocyte: 323.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011825, HPA049473" Approved Supported Microtubules NA NA "Cluster 37: Skin - Keratinization" "Cluster 39: Astrocytes - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 69: Urothelial cells - Basic cellular functions" 35 Microtubules "CAB011825: , HPA049473: " "unprognostic (5.83e-2)" "unprognostic (2.26e-2)" "unprognostic (2.23e-2)" "unprognostic (1.23e-1)" "unprognostic (1.62e-1)" "unprognostic (1.53e-2)" "unprognostic (8.65e-2)" "unprognostic (6.00e-2)" "unprognostic (4.58e-2)" "potential prognostic favorable (2.81e-4)" "unprognostic (2.45e-1)" "unprognostic (8.39e-2)" "unprognostic (1.19e-2)" "unprognostic (2.14e-1)" "potential prognostic favorable (7.96e-4)" "unprognostic (1.31e-3)" "unprognostic (2.37e-3)" "potential prognostic unfavorable (5.10e-4)" "unprognostic (1.57e-1)" "unprognostic (8.15e-2)" "unprognostic (3.00e-1)" "unprognostic (5.97e-2)" "unprognostic (3.07e-1)" "unprognostic (7.98e-2)" GANAB "G2AN, GIIA, GluII, KIAA0088" ENSG00000089597 "Glucosidase II alpha subunit" Q14697 11 62624826-62646726 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 187.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Macrophages, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026874, HPA061426" Enhanced Supported "Endoplasmic reticulum" "Intracellular and membrane" Enzyme NA NA 24000000 "Cluster 13: Non-specific - Mitochondria" "Cluster 22: Epididymis - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 8: Non-specific - Secretory pathway" 27 "Endoplasmic reticulum" "HPA026874: , HPA061426: " "unprognostic (3.40e-2)" "unprognostic (2.15e-1)" "unprognostic (2.01e-1)" "unprognostic (3.62e-3)" "unprognostic (7.31e-2)" "unprognostic (1.41e-2)" "unprognostic (3.20e-1)" "unprognostic (3.39e-3)" "unprognostic (1.68e-1)" "potential prognostic unfavorable (3.55e-4)" "potential prognostic favorable (1.24e-5)" "unprognostic (5.06e-3)" "unprognostic (1.43e-1)" "unprognostic (5.48e-3)" "unprognostic (9.03e-3)" "unprognostic (1.60e-3)" "potential prognostic unfavorable (4.73e-4)" "unprognostic (2.15e-1)" "unprognostic (8.54e-2)" "unprognostic (1.03e-1)" "unprognostic (1.04e-1)" "unprognostic (2.97e-2)" "unprognostic (6.58e-2)" "unprognostic (1.36e-1)" "unprognostic (9.24e-2)" "unprognostic (1.07e-1)" "unprognostic (4.93e-3)" "unprognostic (3.00e-1)" "unprognostic (1.19e-1)" "unprognostic (5.56e-2)" "unprognostic (8.66e-2)" GANC ENSG00000214013 "Glucosidase alpha, neutral C" Q8TET4 15 42273201-42353666 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Glycosidase, Hydrolase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 156.9;Epididymal basal cells: 273.5;Myonuclei: 200.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016949, HPA051522" Approved Approved Cytosol NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 22: Epididymis - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 46: Skeletal myocytes - Muscle structure & formation" Cytosol "HPA016949: , HPA051522: " "unprognostic (1.92e-1)" "unprognostic (2.03e-1)" "unprognostic (1.23e-1)" "unprognostic (5.63e-2)" "unprognostic (9.79e-2)" "unprognostic (5.94e-2)" "unprognostic (1.50e-1)" "unprognostic (2.51e-2)" "unprognostic (1.80e-1)" "unprognostic (2.23e-3)" "unprognostic (1.23e-3)" "potential prognostic favorable (6.85e-4)" "potential prognostic favorable (1.00e-4)" "unprognostic (5.51e-2)" "unprognostic (6.65e-3)" "unprognostic (3.89e-3)" "unprognostic (1.42e-1)" "unprognostic (4.28e-2)" "unprognostic (2.13e-1)" "unprognostic (8.25e-2)" "unprognostic (2.56e-1)" "unprognostic (2.69e-3)" "unprognostic (1.04e-1)" "unprognostic (1.96e-1)" "unprognostic (1.55e-1)" "unprognostic (1.17e-1)" "unprognostic (2.25e-1)" "unprognostic (5.77e-2)" "unprognostic (6.24e-2)" "unprognostic (4.12e-3)" "unprognostic (1.03e-1)" GAP43 "B-50, GAP-43, PP46" ENSG00000172020 "Growth associated protein 43" P17677 3 115623510-115721490 "Plasma proteins, Predicted intracellular proteins, Transporters" "Differentiation, Growth regulation, Neurogenesis" "Calmodulin-binding, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 36 "brain: 473.7" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 234.8;Brain inhibitory neurons: 148.6;Oligodendrocyte progenitor cells: 54.9;Other brain neurons: 248.7;Pituicytes/FSCs: 70.7;Retinal pigment epithelial cells: 81.0;Schwann cells: 33.2" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 45 "Glioblastoma Multiforme (TCGA): 579.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 8 "Neuroblastoma: 120.6" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Minor Salivary Gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004417, HPA013392, HPA015600, CAB078783" Enhanced Supported Enhanced "Plasma membrane" NA NA 29000 "Cluster 10: Brain - Synaptic signal transduction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 98: Neurons - Neurotransmission & signaling" 3 "Plasma membrane" "CAB004417: , CAB078783: , HPA013392: , HPA015600: " "unprognostic (1.02e-1)" "unprognostic (5.11e-2)" "unprognostic (1.05e-3)" "unprognostic (1.36e-2)" "unprognostic (1.28e-1)" "unprognostic (1.12e-2)" "unprognostic (2.91e-1)" "unprognostic (1.91e-1)" "unprognostic (6.80e-2)" "unprognostic (3.98e-3)" "unprognostic (4.18e-2)" "unprognostic (3.42e-2)" "unprognostic (4.79e-2)" "unprognostic (6.91e-2)" "unprognostic (2.79e-2)" GAPDH GAPD ENSG00000111640 "Glyceraldehyde-3-phosphate dehydrogenase" P04406 12 6534512-6538374 "Enzymes, Essential proteins, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Glycolysis, Immunity, Innate immunity, Translation regulation" "Oxidoreductase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "skeletal muscle: 25843.3;tongue: 17635.1" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 15050.4;Esophageal basal cells: 8938.4;Esophageal suprabasal cells: 9709.9;Extravillous trophoblasts: 13577.7;Migrating cytotrophoblasts: 8315.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005197, CAB016392, HPA040067, HPA061280, CAB079968" Supported Enhanced "Nuclear membrane,Vesicles,Plasma membrane,Cytosol" No No 810000000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 148 "Plasma membrane, Cytosol" "Nuclear membrane, Vesicles" "CAB005197: , CAB016392: , CAB079968: , HPA040067: , HPA061280: " "unprognostic (2.72e-2)" "unprognostic (2.17e-1)" "unprognostic (1.38e-1)" "unprognostic (2.95e-1)" "unprognostic (1.41e-1)" "unprognostic (1.03e-1)" "unprognostic (1.26e-2)" "unprognostic (5.08e-2)" "unprognostic (1.00e-3)" "unprognostic (2.31e-3)" "potential prognostic unfavorable (3.31e-5)" "unprognostic (2.74e-3)" "unprognostic (2.57e-2)" "validated prognostic unfavorable (3.95e-6)" "validated prognostic unfavorable (8.80e-10)" "validated prognostic unfavorable (1.61e-7)" "validated prognostic unfavorable (1.15e-5)" "unprognostic (8.44e-2)" "unprognostic (2.50e-1)" "unprognostic (6.92e-2)" "unprognostic (1.08e-1)" "unprognostic (4.63e-3)" "unprognostic (4.52e-2)" "unprognostic (2.01e-1)" "unprognostic (3.57e-1)" "unprognostic (1.46e-1)" "unprognostic (2.78e-1)" "unprognostic (9.28e-2)" "unprognostic (1.08e-1)" "unprognostic (1.38e-1)" "unprognostic (2.95e-3)" GAPDHS "GAPD2, GAPDH-2, GAPDS" ENSG00000105679 "Glyceraldehyde-3-phosphate dehydrogenase, spermatogenic" O14556 19 35533455-35545319 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 20 "testis: 261.4" "Cell type enriched" "Detected in many" 6 "Late spermatids: 14190.3" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in many" 18 "Skin Cutaneous Melanoma (TCGA): 78.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA042666 Enhanced Approved "Nucleoplasm,Centrosome,Principal piece" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 79: Testis - Spermatogenesis" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 49 "Nucleoplasm, Principal piece" Centrosome "HPA042666: " "unprognostic (1.14e-2)" "unprognostic (1.43e-1)" "unprognostic (6.89e-2)" "unprognostic (2.96e-2)" "unprognostic (5.00e-2)" "unprognostic (8.03e-2)" "unprognostic (1.03e-1)" "unprognostic (4.67e-1)" "potential prognostic unfavorable (1.27e-7)" "unprognostic (3.63e-2)" "unprognostic (5.09e-2)" "unprognostic (2.58e-1)" "unprognostic (2.21e-1)" "unprognostic (3.44e-1)" "unprognostic (6.88e-3)" "unprognostic (2.09e-3)" "unprognostic (1.13e-1)" "unprognostic (9.57e-3)" "unprognostic (1.79e-3)" "unprognostic (4.73e-3)" "unprognostic (3.85e-1)" "unprognostic (2.65e-1)" "unprognostic (3.16e-1)" "unprognostic (3.48e-1)" "unprognostic (4.66e-2)" "unprognostic (2.18e-1)" GAPT "C5orf29, FLJ33641" ENSG00000175857 "GRB2 binding adaptor protein, transmembrane" Q8N292 5 58491435-58497090 "Predicted intracellular proteins" "B-cell activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 10.8;lymphoid tissue: 28.2" "Cell type enhanced" "Detected in some" "B-cells: 65.6;cDC: 34.1;Hematopoietic stem cells: 53.4;Macrophages: 27.5;Mast cells: 67.2;Monocyte progenitors: 97.5;monocytes: 51.3;Neutrophil progenitors: 71.0;Neutrophils: 158.7;pDCs: 206.4;Thymocytes: 32.2" "Cell type enriched" "Detected in some" 4 "central nervous system macrophage: 15.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "eosinophil: 647.3" "Lineage enriched" "Detected in many" 5 "granulocytes: 647.3" "Group enriched" "Detected in some" 27 "Leukemia: 16.2;lymphoma: 5.2" "Spleen - B-cells (Spleen)" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA011048, HPA011070" Uncertain Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" "Plasma membrane" "Golgi apparatus, Vesicles" "HPA011048: , HPA011070: " "unprognostic (7.72e-2)" "unprognostic (8.89e-3)" "unprognostic (5.66e-2)" "unprognostic (6.17e-3)" "unprognostic (2.93e-1)" "potential prognostic favorable (3.38e-4)" "unprognostic (6.28e-2)" "unprognostic (1.77e-1)" "potential prognostic favorable (9.05e-4)" "unprognostic (3.13e-1)" "unprognostic (8.89e-2)" "unprognostic (6.11e-2)" "unprognostic (7.80e-2)" "unprognostic (1.53e-2)" "unprognostic (9.68e-2)" "unprognostic (2.81e-1)" "unprognostic (1.15e-1)" "unprognostic (1.03e-1)" "unprognostic (4.60e-2)" "unprognostic (1.15e-2)" "unprognostic (6.80e-2)" GAPVD1 "DKFZP434C212, KIAA1521" ENSG00000165219 "GTPase activating protein and VPS9 domains 1" Q14C86 9 125261794-125367207 "Predicted intracellular proteins" Endocytosis "GTPase activation, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029386, HPA029387, HPA074882" Uncertain Supported "Plasma membrane,Cytosol" NA NA 40000 "Cluster 35: Neutrophils - Protein binding" "Cluster 61: Non-specific - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Transcription" 31 "Plasma membrane" Cytosol "HPA029386: , HPA029387: , HPA074882: " "unprognostic (1.57e-1)" "unprognostic (2.24e-3)" "unprognostic (2.76e-1)" "unprognostic (2.99e-1)" "unprognostic (3.38e-1)" "unprognostic (7.83e-3)" "unprognostic (6.46e-2)" "unprognostic (2.36e-2)" "unprognostic (1.40e-1)" "unprognostic (9.51e-3)" "validated prognostic favorable (5.72e-7)" "validated prognostic favorable (1.32e-4)" "unprognostic (5.55e-2)" "unprognostic (9.55e-2)" "unprognostic (7.68e-2)" "unprognostic (4.03e-2)" "unprognostic (8.39e-2)" "unprognostic (1.62e-1)" "unprognostic (4.57e-2)" "unprognostic (1.06e-1)" "unprognostic (1.18e-2)" "unprognostic (3.89e-1)" "unprognostic (4.18e-2)" "unprognostic (9.41e-2)" "potential prognostic favorable (7.06e-4)" "unprognostic (6.26e-2)" "unprognostic (1.90e-1)" "unprognostic (2.42e-1)" "unprognostic (1.93e-1)" "unprognostic (2.97e-2)" "unprognostic (2.31e-1)" GAR1 NOLA1 ENSG00000109534 "GAR1 ribonucleoprotein" Q9NY12 4 109815510-109824740 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 116.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059098 Supported Approved "Nucleoplasm,Nucleoli fibrillar center" NA Yes 44000 "Cluster 24: Non-specific - Transcription" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 17: Non-specific - RNA processing" 30 "Nucleoplasm, Nucleoli fibrillar center" "HPA059098: " "unprognostic (8.29e-2)" "unprognostic (2.20e-1)" "unprognostic (2.58e-1)" "unprognostic (4.00e-2)" "unprognostic (3.30e-1)" "unprognostic (3.01e-2)" "unprognostic (1.00e-1)" "unprognostic (1.37e-1)" "unprognostic (4.59e-3)" "unprognostic (1.29e-1)" "unprognostic (4.68e-3)" "unprognostic (4.27e-2)" "unprognostic (1.01e-2)" "validated prognostic unfavorable (1.33e-5)" "validated prognostic unfavorable (3.31e-4)" "validated prognostic unfavorable (4.78e-4)" "validated prognostic unfavorable (6.17e-5)" "unprognostic (2.64e-1)" "unprognostic (5.24e-2)" "unprognostic (7.72e-2)" "unprognostic (3.15e-1)" "unprognostic (1.55e-3)" "unprognostic (2.25e-3)" "unprognostic (3.10e-2)" "potential prognostic favorable (9.06e-5)" "unprognostic (1.47e-1)" "unprognostic (1.58e-1)" "unprognostic (1.24e-1)" "unprognostic (1.95e-1)" "unprognostic (1.83e-2)" "potential prognostic favorable (3.16e-4)" GAREM1 "C18orf11, FAM59A, FLJ21610, GAREM" ENSG00000141441 "GRB2 associated regulator of MAPK1 subtype 1" Q9H706 18 32124877-32470882 "Predicted intracellular proteins" Mitogen "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 28.2" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 867.7;Pituicytes/FSCs: 1824.3;Renal connecting tubule cells: 662.8;Urothelial cells: 1482.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 1.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Spleen - Fibroblasts_1, Stomach - Gastric mucous cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040709, HPA042046" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 8: Pancreas - Proteolysis" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 69: Urothelial cells - Basic cellular functions" 14 Nucleoplasm Cytosol "HPA040709: , HPA042046: " "unprognostic (3.44e-2)" "unprognostic (2.12e-1)" "unprognostic (1.71e-1)" "unprognostic (4.78e-3)" "unprognostic (6.30e-3)" "unprognostic (4.54e-1)" "unprognostic (2.68e-2)" "unprognostic (2.03e-2)" "unprognostic (1.71e-2)" "validated prognostic favorable (1.91e-9)" "validated prognostic favorable (3.43e-5)" "unprognostic (2.78e-2)" "unprognostic (4.51e-3)" "unprognostic (3.02e-1)" "unprognostic (1.29e-1)" "unprognostic (3.90e-1)" "unprognostic (1.49e-1)" "unprognostic (3.16e-2)" "unprognostic (1.44e-1)" "potential prognostic unfavorable (5.02e-5)" "unprognostic (2.02e-1)" "unprognostic (3.61e-2)" "unprognostic (7.79e-2)" "unprognostic (8.27e-2)" "unprognostic (2.84e-1)" "unprognostic (1.63e-1)" "unprognostic (2.27e-2)" "unprognostic (1.78e-2)" "unprognostic (2.67e-1)" GAREM2 "FAM59B, FLJ00375, GAREML, KIAA2038" ENSG00000157833 "GRB2 associated regulator of MAPK1 subtype 2" Q75VX8 2 26173088-26189663 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 24.0;parathyroid gland: 21.5" "Cell type enhanced" "Detected in many" "Astrocytes: 52.3;Bergmann glia: 39.9;Early spermatids: 12.4;Late spermatids: 11.1;Müller glia: 31.8;Oligodendrocyte progenitor cells: 11.6" "Group enriched" "Detected in many" 4 "astrocyte: 57.2;Bergmann glia: 40.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071575 Approved Cytosol NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 28: Astrocytes - Homeostasis & neuron support" 1 Cytosol "HPA071575: " "unprognostic (4.85e-2)" "unprognostic (5.52e-2)" "unprognostic (1.94e-2)" "unprognostic (1.48e-1)" "unprognostic (1.60e-1)" "unprognostic (4.68e-2)" "potential prognostic favorable (7.20e-4)" "unprognostic (1.75e-1)" "unprognostic (5.85e-3)" "unprognostic (3.28e-1)" "unprognostic (4.21e-2)" "unprognostic (4.19e-2)" "unprognostic (1.29e-2)" "unprognostic (9.63e-3)" "unprognostic (4.88e-2)" "unprognostic (1.97e-2)" "unprognostic (2.91e-1)" "unprognostic (5.57e-2)" "unprognostic (3.58e-1)" "unprognostic (5.78e-2)" "unprognostic (3.59e-2)" "unprognostic (9.40e-2)" "unprognostic (6.16e-2)" "unprognostic (2.12e-2)" "unprognostic (9.36e-2)" "unprognostic (1.65e-1)" "unprognostic (8.08e-3)" "unprognostic (9.77e-2)" GARIN1A "FAM137B, FAM71F2, GARI" ENSG00000205085 "Golgi associated RAB2 interactor 1A" Q6NXP2 7 128671693-128687877 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 5.7" "Cell type enriched" "Detected in many" 6 "Late spermatids: 1098.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 1.6" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Adipose visceral - Adipocytes (Visceral), Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA020513, HPA024248" Enhanced Approved Nucleoplasm NA NA "Cluster 47: Testis - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 2 Nucleoplasm "HPA020513: , HPA024248: " "unprognostic (8.55e-2)" "potential prognostic unfavorable (7.28e-4)" "unprognostic (5.15e-2)" "unprognostic (1.75e-1)" "unprognostic (6.24e-2)" "unprognostic (2.44e-2)" "unprognostic (1.13e-2)" "unprognostic (6.34e-2)" "unprognostic (3.11e-3)" "unprognostic (4.97e-2)" "unprognostic (1.36e-1)" "unprognostic (1.48e-1)" GARIN1B "FAM137A, FAM71F1, GARI-L1, NYD-SP18" ENSG00000135248 "Golgi associated RAB2 interactor 1B" Q96KD3 7 128709061-128731743 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 90 "testis: 88.5" "Group enriched" "Detected in many" 6 "Early spermatids: 1409.4;Late spermatids: 3032.4" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in single" 14 "Testicular Germ Cell Tumor (TCGA): 8.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "testis cancer: 1.3" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA021409 Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus,Cytosol" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 51: Neurons - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" "Nuclear bodies, Golgi apparatus" "Nucleoplasm, Cytosol" "HPA021409: " "unprognostic (1.13e-1)" "unprognostic (1.34e-1)" "unprognostic (1.47e-1)" GARIN2 "C14orf54, FAM71D, GARI-L2" ENSG00000172717 "Golgi associated RAB2 interactor family member 2" Q8N9W8 14 67189393-67228550 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 26 "testis: 22.4" "Group enriched" "Detected in many" 7 "Early spermatids: 311.7;Late spermatids: 432.0" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "thyroid cancer: 1.5" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" GARIN3 "FAM71B, GARI-L3, MGC26988" ENSG00000170613 "Golgi associated RAB2B interactor family member 3" Q8TC56 5 157161846-157166264 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 299 "testis: 29.8" "Group enriched" "Detected in some" 33 "Early spermatids: 1137.0;Late spermatids: 524.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA039478, HPA040771" Enhanced NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" "HPA039478: , HPA040771: " GARIN4 "FAM71A, FLJ32796, GARI-L4" ENSG00000162771 "Golgi associated RAB2 interactor family member 4" Q8IYT1 1 212624474-212626775 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 99 "testis: 74.6" "Group enriched" "Detected in many" 26 "Early spermatids: 1546.5;Late spermatids: 601.7" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "white matter: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA028462 Enhanced NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 2 "HPA028462: " GARIN5A "FAM71E1, GARIL5" ENSG00000142530 "Golgi associated RAB2 interactor 5A" Q6IPT2 19 50466785-50476848 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "testis: 68.4" "Group enriched" "Detected in many" 5 "Early spermatids: 2395.7;Late spermatids: 4822.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Prostate - Prostate glandular cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048111 Approved "Nucleoli fibrillar center" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 79: Testis - Spermatogenesis" "Cluster 45: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" "Nucleoli fibrillar center" "HPA048111: " "unprognostic (1.81e-2)" "unprognostic (9.64e-2)" "unprognostic (1.23e-1)" "unprognostic (1.19e-1)" "unprognostic (1.44e-1)" "unprognostic (2.79e-2)" "unprognostic (1.13e-2)" "potential prognostic unfavorable (6.57e-5)" "unprognostic (2.16e-1)" "unprognostic (9.85e-3)" "unprognostic (4.10e-2)" "unprognostic (5.40e-2)" "unprognostic (1.21e-1)" "unprognostic (1.61e-1)" "unprognostic (2.28e-1)" "unprognostic (2.36e-2)" "unprognostic (3.06e-2)" "unprognostic (2.79e-1)" "unprognostic (3.15e-2)" "unprognostic (6.11e-3)" "unprognostic (1.14e-1)" "unprognostic (3.87e-2)" "potential prognostic favorable (4.51e-4)" "unprognostic (1.94e-1)" "unprognostic (2.82e-1)" "unprognostic (1.27e-1)" "unprognostic (5.73e-2)" "unprognostic (2.82e-3)" GARIN5B "C19orf16, DKFZp434G1729, FAM71E2" ENSG00000180043 "Golgi associated RAB2 interactor family member 5B" Q8N5Q1 19 55354908-55363260 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 250 "testis: 26.3" "Group enriched" "Detected in some" 5 "Early spermatids: 5.2;Late spermatids: 16.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells, Lung - Respiratory ciliated cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 1 "unprognostic (2.71e-1)" GARIN6 "FAM71C, MGC39520" ENSG00000180219 "Golgi associated RAB2 interactor family member 6" Q8NEG0 12 99647753-99650114 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 260 "testis: 31.7" "Group enriched" "Detected in some" 42 "Early spermatids: 419.3;Late spermatids: 746.5" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebellum: 15.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 2: Neurons - Nucleosome" "Cluster 6: Leukemia - Signal transduction" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 19 GARNL3 "bA356B19.1, DKFZp761J1523" ENSG00000136895 "GTPase activating Rap/RanGAP domain like 3" Q5VVW2 9 127224265-127393660 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.2" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 177.1;Adrenal medulla cells: 265.9;Astrocytes: 221.2;Brain excitatory neurons: 203.5;Brain inhibitory neurons: 190.5;Cardiomyocytes: 221.4;Endometrial stromal cells: 235.5;Microglia: 181.0;Oligodendrocytes: 207.7;Pituitary stem cells: 197.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.0" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Neuroblastoma: 7.4" "Adipose subcutaneous - Smooth muscle cells, Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Kidney - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028757, HPA074886" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 34: Non-specific - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" Vesicles Nucleoplasm "HPA028757: , HPA074886: " "unprognostic (1.07e-2)" "unprognostic (1.73e-1)" "unprognostic (1.01e-1)" "unprognostic (4.49e-2)" "unprognostic (4.47e-3)" "unprognostic (2.80e-2)" "potential prognostic favorable (4.99e-11)" "unprognostic (1.50e-2)" "unprognostic (3.70e-1)" "potential prognostic favorable (8.68e-4)" "unprognostic (2.73e-1)" "unprognostic (3.49e-1)" "unprognostic (1.33e-3)" "unprognostic (9.81e-3)" "unprognostic (2.24e-1)" "unprognostic (3.15e-1)" "unprognostic (1.16e-1)" "unprognostic (1.06e-1)" "unprognostic (1.79e-1)" "unprognostic (1.66e-1)" "unprognostic (1.59e-2)" "potential prognostic unfavorable (7.09e-4)" GARRE1 KIAA0355 ENSG00000166398 "Granule associated Rac and RHOG effector 1" O15063 19 34254552-34355566 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 185.5;Vascular endothelial cells: 129.7" "Cell type enhanced" "Detected in all" "endothelial cell: 325.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Prostate - Endothelial cells, Spleen - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014570 Uncertain Approved Nucleoplasm NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 6: Non-specific - Immune response" "Cluster 4: Non-specific - Transcription" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 12 Nucleoplasm "HPA014570: " "unprognostic (8.63e-2)" "unprognostic (1.43e-2)" "potential prognostic unfavorable (6.87e-4)" "unprognostic (3.34e-1)" "unprognostic (3.29e-2)" "unprognostic (6.25e-2)" "unprognostic (1.62e-1)" "unprognostic (2.35e-2)" "unprognostic (7.91e-2)" "validated prognostic favorable (2.17e-7)" "validated prognostic favorable (2.46e-5)" "unprognostic (3.26e-1)" "unprognostic (4.13e-1)" "unprognostic (2.07e-1)" "unprognostic (2.98e-1)" "unprognostic (1.27e-1)" "unprognostic (8.67e-2)" "unprognostic (1.06e-3)" "unprognostic (6.09e-2)" "unprognostic (2.95e-1)" "unprognostic (1.17e-1)" "unprognostic (1.57e-1)" "unprognostic (5.95e-3)" "unprognostic (1.12e-3)" "unprognostic (9.44e-3)" "unprognostic (4.98e-2)" "unprognostic (2.49e-1)" "unprognostic (2.52e-2)" "unprognostic (2.75e-1)" GARS1 "CMT2D, DSMAV, GARS, GlyRS, SMAD1" ENSG00000106105 "Glycyl-tRNA synthetase 1" P41250 7 30580533-30634033 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Hydrolase, Ligase, Transferase" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017896, HPA019097" Enhanced Supported Cytosol "Intracellular and membrane" Enzyme NA NA 830000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 35 Cytosol "HPA017896: , HPA019097: " "unprognostic (2.21e-1)" "potential prognostic unfavorable (1.64e-4)" "unprognostic (9.19e-2)" "unprognostic (5.69e-2)" "unprognostic (4.48e-2)" "unprognostic (3.20e-1)" "unprognostic (1.75e-3)" "unprognostic (1.05e-3)" "potential prognostic unfavorable (2.02e-5)" "potential prognostic unfavorable (5.10e-6)" "unprognostic (2.39e-2)" "unprognostic (1.25e-1)" "potential prognostic unfavorable (8.15e-7)" "unprognostic (1.15e-3)" "unprognostic (2.81e-3)" "unprognostic (2.36e-1)" "unprognostic (3.68e-2)" "unprognostic (3.72e-2)" "unprognostic (2.20e-2)" "unprognostic (5.75e-2)" "unprognostic (6.66e-3)" "unprognostic (5.24e-3)" "unprognostic (1.49e-1)" "unprognostic (3.59e-2)" "unprognostic (2.05e-1)" "unprognostic (2.09e-2)" "unprognostic (1.99e-1)" "unprognostic (1.25e-1)" "unprognostic (1.04e-1)" GART "GARS-AIRS-GART, PGFT, PRGS" ENSG00000159131 "Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase" P22102 21 33503931-33543491 "Enzymes, Essential proteins, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Purine biosynthesis" "Ligase, Multifunctional enzyme, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 188.8;Epicardial cells: 141.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002119, HPA005779" Approved Approved Mitochondria,Cytosol NA NA 350000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 39: Testis - Nuclear processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 17: Non-specific - RNA processing" 15 Cytosol Mitochondria "HPA002119: , HPA005779: " "unprognostic (2.44e-1)" "unprognostic (2.89e-2)" "unprognostic (2.25e-2)" "potential prognostic unfavorable (2.99e-4)" "unprognostic (6.12e-2)" "unprognostic (3.20e-1)" "unprognostic (7.58e-2)" "unprognostic (5.20e-2)" "unprognostic (5.69e-2)" "unprognostic (4.46e-2)" "potential prognostic favorable (3.72e-4)" "unprognostic (3.54e-1)" "unprognostic (5.05e-3)" "unprognostic (1.24e-2)" "potential prognostic unfavorable (4.32e-4)" "unprognostic (2.03e-3)" "unprognostic (2.09e-2)" "unprognostic (2.41e-1)" "unprognostic (2.93e-1)" "unprognostic (1.33e-1)" "unprognostic (2.83e-1)" "potential prognostic unfavorable (5.85e-4)" "unprognostic (2.45e-1)" "unprognostic (4.06e-3)" "unprognostic (1.85e-3)" "unprognostic (7.51e-2)" "unprognostic (6.82e-2)" "unprognostic (5.59e-2)" "unprognostic (1.73e-1)" "unprognostic (8.05e-2)" "unprognostic (2.29e-1)" GAS1 ENSG00000180447 "Growth arrest specific 1" P54826 9 86944362-86947506 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Growth arrest" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 80.9" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 54.4;Breast myoepithelial cells: 111.9;Decidual stromal cells: 271.8;Fibroblasts: 166.3;Medullary thymic epithelial cells: 122.4;Mesothelial cells: 146.7;Müller glia: 99.6;Myosatellite cells: 56.1;Podocytes: 61.9;Prostatic glandular cells: 70.7;Smooth muscle cells: 48.6" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 16.6" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 37.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 35.8;Sarcoma: 24.3" "Adipose subcutaneous - Mast cells, Adipose visceral - Mesothelial cells, Adrenal gland - Fibroblasts, Breast - Fibroblasts, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB024164, HPA036085, HPA066902" Approved Approved "Nuclear speckles" NA NA 39000 "Cluster 75: Ovary - Mixed function" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 108: Fibroblasts - ECM organization" "Nuclear speckles" "CAB024164: , HPA036085: , HPA066902: " "unprognostic (1.25e-1)" "unprognostic (1.88e-1)" "unprognostic (2.14e-1)" "unprognostic (1.09e-1)" "unprognostic (1.06e-2)" "unprognostic (1.68e-1)" "unprognostic (8.44e-2)" "unprognostic (1.47e-1)" "unprognostic (3.41e-2)" "unprognostic (6.37e-2)" "unprognostic (1.83e-2)" "unprognostic (2.20e-3)" "unprognostic (1.56e-2)" "unprognostic (1.49e-2)" "unprognostic (2.54e-1)" "unprognostic (5.30e-2)" "unprognostic (4.94e-2)" "unprognostic (3.42e-1)" "potential prognostic unfavorable (1.93e-4)" "unprognostic (1.46e-3)" "unprognostic (8.06e-3)" "unprognostic (3.12e-1)" "unprognostic (2.72e-2)" "potential prognostic unfavorable (1.18e-4)" "unprognostic (4.58e-2)" "unprognostic (1.84e-1)" "unprognostic (1.04e-3)" "unprognostic (6.57e-2)" "potential prognostic unfavorable (3.05e-5)" "unprognostic (1.15e-1)" GAS2 ENSG00000148935 "Growth arrest specific 2" O43903 11 22625509-22813001 "Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell shape, Growth arrest" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 37.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 227.0;Gonadotrophs: 461.0;Hepatocytes: 291.4;Myonuclei: 744.7;Retinal ganglion cells: 173.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 14.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 7 "Myeloma: 64.1" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Pituitary gland - Gonadotropes, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058904 Enhanced Approved "Nucleoplasm,Nucleoli,Plasma membrane,Cytosol" Yes NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 45: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 55: Myocytes - Oxidative muscle function" "Plasma membrane, Cytosol" "Nucleoplasm, Nucleoli" "HPA058904: " "unprognostic (6.64e-2)" "unprognostic (3.78e-1)" "unprognostic (7.94e-2)" "unprognostic (1.37e-2)" "unprognostic (9.05e-2)" "unprognostic (1.57e-1)" "unprognostic (1.65e-1)" "unprognostic (2.02e-1)" "unprognostic (1.32e-3)" "potential prognostic favorable (8.42e-4)" "unprognostic (3.41e-1)" "unprognostic (3.52e-2)" "unprognostic (1.10e-1)" "unprognostic (4.85e-2)" "unprognostic (6.56e-2)" "unprognostic (3.15e-3)" "unprognostic (4.01e-2)" "unprognostic (5.55e-2)" "unprognostic (1.83e-1)" "potential prognostic unfavorable (3.67e-4)" "unprognostic (4.24e-2)" "unprognostic (4.09e-1)" "unprognostic (1.92e-1)" "unprognostic (4.94e-2)" "unprognostic (6.51e-2)" "unprognostic (4.87e-2)" GAS2L1 GAR22 ENSG00000185340 "Growth arrest specific 2 like 1" Q99501 22 29306618-29312787 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Platelets: 1048.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019858 Approved Approved "Plasma membrane,Cell Junctions" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 2: Non-specific - Mixed function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 47: Platelets - Hemostasis" 18 "Plasma membrane" "Cell Junctions" "HPA019858: " "unprognostic (2.37e-1)" "unprognostic (2.68e-1)" "unprognostic (9.42e-2)" "unprognostic (3.11e-1)" "unprognostic (3.83e-2)" "unprognostic (8.91e-2)" "unprognostic (1.33e-1)" "unprognostic (1.94e-2)" "unprognostic (3.63e-1)" "unprognostic (8.45e-3)" "unprognostic (4.62e-3)" "unprognostic (4.59e-2)" "unprognostic (6.82e-3)" "unprognostic (2.18e-2)" "unprognostic (1.68e-1)" "unprognostic (1.58e-3)" "unprognostic (4.14e-1)" "unprognostic (1.09e-2)" "unprognostic (1.60e-1)" "unprognostic (2.04e-1)" "unprognostic (2.51e-1)" "unprognostic (2.80e-1)" "unprognostic (3.06e-1)" "unprognostic (4.13e-2)" "unprognostic (1.48e-1)" "unprognostic (9.86e-2)" "unprognostic (1.94e-1)" "unprognostic (8.00e-2)" "unprognostic (1.62e-1)" "unprognostic (5.89e-3)" "unprognostic (3.00e-1)" GAS2L2 GAR17 ENSG00000270765 "Growth arrest specific 2 like 2" Q8NHY3 17 35744511-35753239 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "choroid plexus: 8.5;fallopian tube: 15.0" "Group enriched" "Detected in some" 4 "Endometrial ciliated cells: 27.4;Ependymal cells: 15.0;Epididymal efferent duct ciliated cells: 21.0;Fallopian tube ciliated cells: 54.6;Respiratory ciliated cells: 54.9" "Cell type enriched" "Detected in some" 5 "ependymal cell: 17.6" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 2.9" "Region enhanced" "Detected in many" "choroid plexus: 13.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "cervical cancer: 1.3" "Lung - Respiratory ciliated cells, Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA044370 Enhanced NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 7: Liver cancer - Metabolism" "Cluster 107: Ciliated cells - Cilia assembly & function" 37 "HPA044370: " "unprognostic (1.41e-1)" "unprognostic (2.00e-2)" "unprognostic (1.59e-1)" GAS2L3 ENSG00000139354 "Growth arrest specific 2 like 3" Q86XJ1 12 100573683-100628288 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Colonocytes: 67.8;Enteric transient amplifying cells: 65.7;Goblet cells: 73.3;Hofbauer cells: 78.2;Macrophages: 104.3;Melanocytes: 54.3;Monocyte progenitors: 66.2;monocytes: 56.3;Schwann cells: 203.6;Syncytiotrophoblasts: 101.8" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 26.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.3;myeloid DC: 1.5" "Group enriched" "Detected in many" 6 "dendritic cells: 1.5;monocytes: 1.3" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Spleen - Macrophages, Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in many" "Region enriched" "Detected in some" 4 "spinal cord: 18.9" HPA048593 Approved NA Yes "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 48: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 12 "HPA048593: " "unprognostic (6.91e-3)" "unprognostic (9.83e-2)" "unprognostic (1.45e-1)" "unprognostic (6.20e-3)" "unprognostic (9.64e-2)" "unprognostic (1.00e-1)" "unprognostic (1.23e-1)" "unprognostic (1.07e-1)" "unprognostic (1.76e-1)" "unprognostic (1.22e-3)" "potential prognostic favorable (6.82e-4)" "unprognostic (1.46e-2)" "unprognostic (1.64e-3)" "potential prognostic unfavorable (2.28e-7)" "unprognostic (2.37e-2)" "unprognostic (1.74e-2)" "unprognostic (1.45e-2)" "unprognostic (8.11e-2)" "unprognostic (3.02e-1)" "unprognostic (1.88e-1)" "unprognostic (2.31e-1)" "unprognostic (1.15e-1)" "unprognostic (2.74e-2)" "unprognostic (3.71e-3)" "unprognostic (1.21e-1)" "unprognostic (1.03e-1)" "unprognostic (3.42e-2)" "unprognostic (2.53e-1)" "unprognostic (5.11e-2)" GAS6 "AXLLG, AXSF, DKFZp666G247, FLJ34709" ENSG00000183087 "Growth arrest specific 6" Q14393 13 113820549-113864076 "Predicted secreted proteins" "Growth regulation, Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "blood vessel: 838.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 372.0;Breast myoepithelial cells: 333.2;Fallopian secretory cells: 500.7;Granulosa cells: 304.9;Retinal horizontal cells: 248.4;Smooth muscle cells: 307.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "plasmacytoid DC: 70.8" "Lineage enriched" "Detected in many" 50 "dendritic cells: 70.8" "Cancer enhanced" "Detected in all" "Bile duct cancer: 260.5" "Breast - Fibroblasts, Pancreas - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008275, HPA056080" Approved Approved "Centriolar satellite,Cytosol" "Secreted to blood" Other NA NA 8900000 5000000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 44: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 2 Cytosol "Centriolar satellite" "HPA008275: , HPA056080: " "unprognostic (3.17e-2)" "unprognostic (2.43e-1)" "unprognostic (2.70e-2)" "unprognostic (1.36e-1)" "unprognostic (1.31e-1)" "unprognostic (1.89e-1)" "unprognostic (3.31e-3)" "unprognostic (8.36e-2)" "unprognostic (1.75e-1)" "unprognostic (1.75e-1)" "potential prognostic favorable (1.82e-4)" "unprognostic (2.16e-2)" "unprognostic (2.89e-1)" "unprognostic (7.14e-3)" "potential prognostic favorable (6.99e-7)" "unprognostic (4.42e-2)" "unprognostic (9.78e-2)" "unprognostic (3.93e-3)" "unprognostic (1.09e-1)" "unprognostic (1.60e-2)" "unprognostic (1.32e-1)" "unprognostic (1.31e-1)" "unprognostic (2.99e-2)" "unprognostic (2.73e-1)" "unprognostic (2.36e-2)" "unprognostic (3.31e-2)" "unprognostic (5.00e-1)" "unprognostic (3.63e-1)" "unprognostic (6.72e-3)" "unprognostic (1.32e-1)" "unprognostic (1.05e-1)" GAS7 "KIAA0394, MGC1348" ENSG00000007237 "Growth arrest specific 7" O60861 17 9910606-10198606 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "brain: 176.2" "Cell type enhanced" "Detected in many" "cDC: 349.5;Choroid plexus epithelial cells: 331.6;Fibro-adipogenic progenitors: 699.2;Macrophages: 385.3;Mast cells: 319.8;monocytes: 603.5;Neutrophils: 740.1;Schwann cells: 526.3;Sertoli cells: 279.2" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 4 "Skin Cutaneous Melanoma (TCGA): 132.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 26.3" "Group enriched" "Detected in many" 4 "granulocytes: 17.1;monocytes: 26.3" "Cancer enhanced" "Detected in many" "skin cancer: 129.9" "Adrenal gland - Macrophages, Breast - Fibroblasts, Colon - Enteric glia cells, Lung - Fibroblasts_2, Pituitary gland - Undifferentiated cells (Pituitary gland), Skeletal muscle - Fibroblasts, Skin - Keratinocyte (granular), Stomach - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004838, HPA064678" Enhanced Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 27: Cerebellum - Synaptic function" "Cluster 53: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 7 "Plasma membrane" "Actin filaments, Focal adhesion sites" "HPA004838: , HPA064678: " "unprognostic (6.01e-2)" "unprognostic (3.30e-2)" "unprognostic (3.85e-2)" "unprognostic (1.95e-1)" "unprognostic (7.01e-2)" "unprognostic (4.06e-2)" "unprognostic (2.60e-1)" "unprognostic (1.54e-3)" "unprognostic (3.78e-2)" "unprognostic (2.69e-1)" "unprognostic (1.32e-1)" "unprognostic (2.72e-1)" "unprognostic (9.87e-2)" "unprognostic (1.01e-2)" "unprognostic (1.10e-1)" "unprognostic (9.01e-3)" "unprognostic (1.24e-1)" "unprognostic (2.00e-2)" "unprognostic (8.10e-2)" "unprognostic (4.22e-3)" "potential prognostic unfavorable (4.67e-5)" "unprognostic (1.90e-1)" "unprognostic (1.18e-1)" "unprognostic (7.22e-2)" "unprognostic (4.64e-2)" "unprognostic (2.42e-3)" "unprognostic (4.29e-2)" "unprognostic (1.09e-1)" "unprognostic (2.89e-1)" "unprognostic (1.21e-2)" "unprognostic (2.60e-1)" GAS8 "DRC4, GAS11" ENSG00000141013 "Growth arrest specific 8" O95995 16 90019629-90044975 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Ciliopathy, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 220.7;Fallopian tube ciliated cells: 108.0;Late spermatids: 408.8;Respiratory ciliated cells: 124.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Spleen - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041311, HPA048238" Approved Supported "Golgi apparatus,Vesicles,Plasma membrane,Primary cilium,Cytosol,Mid piece,Principal piece,End piece" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 21: Testis - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 99 "Golgi apparatus, Plasma membrane, Primary cilium, Cytosol, Mid piece, Principal piece, End piece" Vesicles "HPA041311: , HPA048238: " "unprognostic (7.22e-2)" "unprognostic (9.38e-2)" "unprognostic (1.42e-1)" "unprognostic (2.50e-2)" "unprognostic (3.01e-1)" "unprognostic (5.22e-2)" "unprognostic (1.20e-1)" "unprognostic (2.87e-1)" "unprognostic (1.37e-1)" "unprognostic (2.39e-2)" "potential prognostic favorable (6.37e-7)" "unprognostic (4.25e-2)" "potential prognostic favorable (1.79e-7)" "unprognostic (1.70e-1)" "unprognostic (1.84e-1)" "unprognostic (1.78e-1)" "unprognostic (2.51e-1)" "unprognostic (4.10e-2)" "unprognostic (3.96e-2)" "unprognostic (1.38e-1)" "unprognostic (4.64e-3)" "unprognostic (4.16e-2)" "unprognostic (4.51e-3)" "unprognostic (1.47e-1)" "unprognostic (3.16e-1)" "unprognostic (1.34e-1)" "unprognostic (4.23e-1)" "unprognostic (6.06e-2)" "unprognostic (6.90e-2)" "unprognostic (1.13e-1)" "unprognostic (1.22e-1)" GASK1A "C3orf41, DKFZP434B172, FAM198A" ENSG00000144649 "Golgi associated kinase 1A" Q9UFP1 3 42979087-43067898 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 18.7;Bergmann glia: 26.4;Decidual stromal cells: 35.2;Epididymal efferent duct ciliated cells: 16.8;Fallopian tube ciliated cells: 23.8;Fibroblasts: 14.6;Hepatocytes: 27.7;Leydig cells: 25.2;Müller glia: 20.5;Peritubular myoid cells: 43.6;Pituitary stem cells: 15.2" "Cell type enhanced" "Detected in many" "astrocyte: 27.5;Bergmann glia: 25.5" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 10.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 2.0;Neuroblastoma: 1.9" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblasts_2, Pituitary gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047726 Approved Supported Vesicles "Secreted - unknown location" "No annotated function" NA NA 400000 "Cluster 36: Brain & Liver - Signaling" "Cluster 44: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 108: Fibroblasts - ECM organization" Vesicles "HPA047726: " "unprognostic (3.94e-2)" "unprognostic (1.22e-2)" "unprognostic (9.08e-2)" "unprognostic (3.06e-1)" "unprognostic (1.35e-1)" "unprognostic (1.83e-3)" "unprognostic (8.84e-2)" "unprognostic (2.68e-1)" "unprognostic (1.52e-1)" "unprognostic (1.63e-1)" "unprognostic (1.85e-1)" "unprognostic (3.24e-1)" "unprognostic (9.49e-2)" "unprognostic (1.76e-2)" "unprognostic (6.93e-2)" "unprognostic (1.01e-2)" GASK1B "C4orf18, DKFZp434L142, ENED, FAM198B, FLJ38155" ENSG00000164125 "Golgi associated kinase 1B" Q6UWH4 4 158124474-158173318 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 194.5" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 407.4;Bergmann glia: 116.0;Breast myoepithelial cells: 101.6;Cardiomyocytes: 146.0;Endometrial stromal cells: 101.2;Hofbauer cells: 127.8;Kupffer cells: 185.5;Macrophages: 97.9;Microglia: 120.2;Monocyte progenitors: 135.7;monocytes: 193.0;Vascular endothelial cells: 153.4" "Cell type enhanced" "Detected in many" "Bergmann glia: 160.3;central nervous system macrophage: 151.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 34 "classical monocyte: 50.8;intermediate monocyte: 28.9;myeloid DC: 15.1;non-classical monocyte: 14.0" "Group enriched" "Detected in many" 41 "dendritic cells: 15.1;monocytes: 50.8" "Cancer enhanced" "Detected in many" "Rhabdoid: 61.7" "Adrenal gland - Adrenal cortex cells, Colon - Enteric glia cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA007227 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus,Cytosol" NA NA 49000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" Nucleoplasm "Nucleoli fibrillar center, Golgi apparatus, Cytosol" "HPA007227: " "unprognostic (6.29e-2)" "unprognostic (1.39e-1)" "unprognostic (1.44e-2)" "unprognostic (2.77e-3)" "unprognostic (1.71e-1)" "unprognostic (2.58e-2)" "unprognostic (5.05e-3)" "unprognostic (6.76e-2)" "unprognostic (6.64e-2)" "potential prognostic favorable (9.93e-7)" "unprognostic (2.81e-3)" "potential prognostic unfavorable (5.54e-4)" "unprognostic (3.03e-2)" "unprognostic (1.55e-1)" "unprognostic (1.20e-1)" "unprognostic (7.98e-3)" "unprognostic (5.04e-2)" "unprognostic (3.68e-2)" "unprognostic (2.03e-3)" "unprognostic (1.29e-1)" "unprognostic (8.35e-2)" "unprognostic (1.14e-1)" "unprognostic (1.01e-1)" "unprognostic (9.41e-2)" "unprognostic (2.94e-2)" "potential prognostic unfavorable (2.29e-4)" "unprognostic (4.62e-2)" "unprognostic (7.50e-3)" "unprognostic (1.95e-1)" GAST GAS ENSG00000184502 Gastrin P01350 17 41712331-41715969 "Cancer-related genes, FDA approved drug targets, Predicted secreted proteins" Hormone "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 167 "stomach 1: 9038.0" "Group enriched" "Detected in some" 11 "Endometrial glandular cells: 171.0;Neuroendocrine cells: 382.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Pancreatic Adenocarcinoma (TCGA): 99.5;Stomach Adenocarcinoma (TCGA): 40.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "cervical cancer: 2.8;colorectal cancer: 2.5;Esophageal cancer: 4.6;Gastric cancer: 9.0;head and neck cancer: 5.9" "Low region specificity" "Detected in many" "Not detected" "Not detected" CAB000038 Enhanced "Secreted to digestive system" Hormone NA NA 120000 "Cluster 60: Stomach - Digestion" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" 23 "CAB000038: " "unprognostic (8.80e-2)" "unprognostic (8.49e-3)" "unprognostic (5.63e-3)" "unprognostic (2.04e-1)" "unprognostic (1.81e-1)" "unprognostic (3.50e-3)" "unprognostic (2.28e-1)" "unprognostic (3.31e-1)" GATA1 "ERYF1, GATA-1, GF1, NF-E1, NFE1" ENSG00000102145 "GATA binding protein 1" P15976 X 48786540-48794311 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 27 "bone marrow: 55.7" "Cell type enhanced" "Detected in some" "Erythrocyte progenitors: 151.7;Erythrocytes: 34.7;Late spermatids: 44.8;Mast cells: 32.3;Megakaryocyte progenitors: 82.7;Megakaryocyte-Erythroid progenitors: 80.7;Megakaryocytes: 315.3;Platelets: 209.1" "Cell type enhanced" "Detected in some" "astrocyte: 1.2;ependymal cell: 2.0;oligodendrocyte: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 6 "eosinophil: 463.2" "Lineage enriched" "Detected in single" 1843 "granulocytes: 463.2" "Cancer enriched" "Detected in single" 261 "Leukemia: 59.8" "Adipose subcutaneous - Mast cells, Colon - Mast cells, Liver - Erythroid cells, Skin - Mast cells, Spleen - Erythrocytes, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA000232, HPA000233, CAB009195" Enhanced Supported Nucleoplasm NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 15: Bone marrow - Innate immune response" "Cluster 11: White matter - Signal transduction" "Cluster 47: Leukemia - Hemostasis" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 37 Nucleoplasm "CAB009195: , HPA000232: , HPA000233: " GATA2 NFE1B ENSG00000179348 "GATA binding protein 2" P23769 3 128479427-128493201 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Phagocytosis, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial luminal cells: 206.9;Extravillous trophoblasts: 355.8;Hematopoietic stem cells: 111.1;Mast cells: 769.7;Megakaryocyte progenitors: 268.3;Megakaryocyte-Erythroid progenitors: 162.6;Migrating cytotrophoblasts: 162.3;Platelets: 176.8;Prostatic club cells: 279.7;Prostatic hillock cells: 124.9;Syncytiotrophoblasts: 367.7" "Cell type enriched" "Detected in some" 11 "endothelial cell: 71.9" "Group enriched" "Detected in many" 4 "Bladder Urothelial Carcinoma (TCGA): 22.5;Kidney Chromophobe (TCGA): 46.1;Prostate Adenocarcinoma (TCGA): 64.4;Uterine Corpus Endometrial Carcinoma (TCGA): 22.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 361 "basophil: 567.4" "Lineage enriched" "Detected in single" 4016 "granulocytes: 567.4" "Cancer enhanced" "Detected in many" "Neuroblastoma: 237.6" "Adrenal gland - Adrenal medulla cells, Pituitary gland - Thyrotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005633, CAB024847" Enhanced Supported Nucleoplasm NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 75: Ovary - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 47: Leukemia - Hemostasis" "Cluster 58: Mast cells - Allergic inflammatory responses" 46 Nucleoplasm "CAB024847: , HPA005633: " "unprognostic (2.91e-2)" "unprognostic (1.11e-1)" "unprognostic (5.59e-2)" "unprognostic (9.60e-2)" "unprognostic (2.41e-2)" "unprognostic (2.14e-2)" "unprognostic (8.77e-2)" "unprognostic (1.95e-1)" "unprognostic (1.67e-1)" "unprognostic (3.13e-1)" "validated prognostic favorable (3.14e-5)" "validated prognostic favorable (4.49e-4)" "unprognostic (2.28e-1)" "unprognostic (1.14e-2)" "unprognostic (6.86e-3)" "unprognostic (3.20e-2)" "unprognostic (4.11e-2)" "unprognostic (6.15e-2)" "unprognostic (2.66e-2)" "potential prognostic unfavorable (8.69e-5)" "unprognostic (1.28e-1)" "unprognostic (3.30e-2)" "unprognostic (1.30e-1)" "unprognostic (1.13e-1)" "unprognostic (4.17e-2)" "unprognostic (2.42e-2)" "unprognostic (9.70e-2)" "unprognostic (9.50e-2)" "unprognostic (1.13e-1)" "unprognostic (2.29e-1)" GATA3 HDR ENSG00000107485 "GATA binding protein 3" P23771 10 8045378-8075198 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Immunity, Innate immunity, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 111.9;skin 1: 169.0" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 487.8;Cytotrophoblasts: 374.2;Extravillous trophoblasts: 1181.3;Migrating cytotrophoblasts: 830.6;Papillary tip epithelial cells: 328.3;Renal collecting duct principal cells: 458.5;Renal connecting tubule cells: 269.8;Syncytiotrophoblasts: 1534.3;Urothelial cells: 464.6" "Group enriched" "Detected in some" 12 "leukocyte: 54.9;midbrain-derived inhibitory: 101.3" "Group enriched" "Detected in many" 10 "Bladder Urothelial Carcinoma (TCGA): 125.8;Breast Invasive Carcinoma (TCGA): 330.3" "Group enriched" "Detected in many" 4 "midbrain: 66.0;pons: 31.2" "Group enriched" "Detected in many" 33 "gdT-cell: 25.0;MAIT T-cell: 32.5;memory CD4 T-cell: 41.5;memory CD8 T-cell: 34.4;naive CD4 T-cell: 24.6;naive CD8 T-cell: 23.7;NK-cell: 39.6;T-reg: 51.4" "Group enriched" "Detected in many" 44 "NK-cells: 39.6;T-cells: 51.4" "Group enriched" "Detected in all" 4 "Bladder cancer: 54.4;breast cancer: 148.0;Neuroblastoma: 204.6" "Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Thyrotropes, Skin - Keratinocyte (other), Stomach - T-cells" "Region enriched" "Detected in single" 7 "midbrain: 6.1" "Group enriched" "Detected in many" 11 "medulla oblongata: 6.8;midbrain: 18.5;pons: 15.4;thalamus: 17.1" "CAB016217, HPA029730" Enhanced Supported Nucleoplasm NA NA "Cluster 1: T-cells - Unknown function" "Cluster 9: Skin - Hair follicle development" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 27: Breast cancer - Unknown function" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." 34 Nucleoplasm "CAB016217: , HPA029730: " "unprognostic (1.11e-3)" "unprognostic (4.06e-1)" "unprognostic (2.94e-1)" "unprognostic (8.58e-2)" "unprognostic (1.31e-2)" "unprognostic (1.23e-2)" "unprognostic (5.60e-2)" "unprognostic (3.94e-2)" "unprognostic (6.49e-3)" "potential prognostic unfavorable (7.40e-5)" "unprognostic (5.01e-3)" "unprognostic (1.83e-1)" "unprognostic (5.79e-2)" "unprognostic (2.15e-1)" "unprognostic (8.79e-2)" "unprognostic (9.01e-2)" "unprognostic (1.13e-1)" "unprognostic (3.48e-1)" "unprognostic (9.04e-3)" "unprognostic (6.77e-2)" "unprognostic (3.30e-3)" "unprognostic (1.21e-2)" "unprognostic (3.66e-1)" "unprognostic (1.67e-1)" "unprognostic (3.64e-2)" "unprognostic (2.01e-1)" "unprognostic (3.46e-1)" GATA4 ENSG00000136574 "GATA binding protein 4" P43694 8 11676959-11760002 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Atrial septal defect, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 80.1;ovary: 85.2;pancreas: 48.3" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 18.3;Foveolar cells: 16.4;Gastric chief cells: 10.9;Gastric progenitor cells: 15.4;Granulosa cells: 30.0;Hepatic stellate cells: 6.5;Late spermatids: 23.3;Leydig cells: 8.9;Mucous neck cells: 14.2;Ovarian stromal cells: 24.2;Pancreatic acinar cells: 11.9;Paneth cells: 7.7;Parietal cells: 8.8;Peritubular myoid cells: 6.8;Sertoli cells: 14.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Stomach Adenocarcinoma (TCGA): 22.3;Testicular Germ Cell Tumor (TCGA): 15.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 15.0" "Heart muscle - Cardiomyocytes" "Not detected" "Not detected" "Not detected" "Not detected" "CAB013125, HPA073899" Uncertain Supported "Nuclear bodies" NA NA "Cluster 70: Non-specific - Protein processing" "Cluster 18: Liver cancer - Metabolism" "Cluster 94: Gonadal somatic cells - Mixed function" 25 "Nuclear bodies" "CAB013125: , HPA073899: " "unprognostic (4.49e-1)" "unprognostic (3.00e-2)" "unprognostic (5.09e-2)" "unprognostic (1.39e-1)" "unprognostic (3.76e-3)" "unprognostic (1.75e-2)" "unprognostic (1.94e-1)" "unprognostic (3.09e-1)" "unprognostic (1.43e-1)" "unprognostic (6.46e-2)" GATA5 "bB379O24.1, GATAS" ENSG00000130700 "GATA binding protein 5" Q9BWX5 20 62463497-62475995 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 11.0;testis: 11.3;urinary bladder: 15.9" "Cell type enhanced" "Detected in some" "Enterocytes: 45.8;Foveolar cells: 15.7;Gastric chief cells: 28.4;Mesothelial cells: 13.3;Mucous neck cells: 18.3;Paneth cells: 19.3;Parietal cells: 19.4;Sertoli cells: 40.2;Smooth muscle cells: 23.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Stomach Adenocarcinoma (TCGA): 8.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 2.8" "Adipose visceral - Mesothelial cells, Kidney - Podocytes, Liver - Hepatic stellate cells, Testis - Sertoli cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA067583 Approved Nucleoplasm,Cytosol NA NA "Cluster 21: Testis - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 1: Enterocytes - Absorption and Digestion" 8 Nucleoplasm Cytosol "HPA067583: " "unprognostic (1.17e-2)" "unprognostic (1.95e-3)" "unprognostic (1.05e-2)" "unprognostic (6.72e-3)" "unprognostic (1.28e-2)" "unprognostic (2.84e-1)" "unprognostic (1.77e-2)" "unprognostic (3.88e-2)" GATA6 ENSG00000141448 "GATA binding protein 6" Q92908 18 22169589-22202528 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Atrial septal defect, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 57.4;ovary: 70.1" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 380.3;Alveolar cells type 2: 202.0;Cardiomyocytes: 182.6;Foveolar cells: 183.6;Gastric chief cells: 156.2;Hepatic stellate cells: 161.4;Mesothelial cells: 209.5;Mucous neck cells: 285.3;Ovarian stromal cells: 151.3;Pancreatic duct cells: 141.1;Parietal cells: 297.0" "Cell type enhanced" "Detected in some" "endothelial cell: 18.6;fibroblast: 17.7;vascular associated smooth muscle cell: 7.4" "Cancer enhanced" "Detected in many" "Stomach Adenocarcinoma (TCGA): 45.3" "Region enriched" "Detected in single" 7 "choroid plexus: 5.9" "Immune cell enriched" "Detected in single" 23 "basophil: 4.0" "Lineage enriched" "Detected in single" 23 "granulocytes: 4.0" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Kidney - Fibroblasts, Minor Salivary Gland - Endothelial cells, Prostate - Fibroblasts, Spleen - Endothelial cells, Testis - Sertoli cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB011581, HPA066629" Approved Supported Nucleoplasm Yes No "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 8: Immune cells - Immune response" "Cluster 66: Non-specific - Mitochondria" "Cluster 18: Adrenal cortex cells - Steroidogensis" 1 Nucleoplasm "CAB011581: , HPA066629: " "unprognostic (1.53e-1)" "unprognostic (1.23e-1)" "unprognostic (1.07e-1)" "unprognostic (1.97e-2)" "unprognostic (1.07e-1)" "unprognostic (8.16e-2)" "unprognostic (1.09e-2)" "unprognostic (4.94e-3)" "unprognostic (5.90e-3)" "unprognostic (1.19e-1)" "potential prognostic unfavorable (1.24e-4)" "unprognostic (2.65e-1)" "unprognostic (3.66e-2)" "unprognostic (1.74e-1)" "unprognostic (8.73e-2)" "unprognostic (1.44e-2)" "unprognostic (8.92e-2)" "unprognostic (7.38e-2)" "unprognostic (3.02e-2)" "unprognostic (1.57e-1)" "unprognostic (2.57e-2)" "unprognostic (3.15e-2)" "unprognostic (2.23e-2)" "unprognostic (7.52e-3)" "potential prognostic unfavorable (6.33e-4)" "unprognostic (1.01e-1)" "unprognostic (1.02e-1)" "unprognostic (3.44e-2)" "unprognostic (2.20e-2)" GATAD1 "FLJ22489, ODAG, RG083M05.2" ENSG00000157259 "GATA zinc finger domain containing 1" Q8WUU5 7 92447482-92460075 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 122.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006105, HPA072785" Enhanced Nucleoplasm Yes No "Cluster 22: Eosinophils - Transcription" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 39: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 34 Nucleoplasm "HPA006105: , HPA072785: " "unprognostic (8.23e-3)" "unprognostic (3.71e-1)" "unprognostic (1.49e-1)" "unprognostic (4.41e-3)" "unprognostic (4.89e-2)" "unprognostic (1.84e-1)" "unprognostic (8.71e-2)" "unprognostic (1.17e-1)" "unprognostic (5.32e-2)" "unprognostic (2.64e-2)" "unprognostic (2.57e-2)" "unprognostic (1.07e-1)" "unprognostic (3.26e-2)" "unprognostic (4.00e-3)" "unprognostic (9.87e-2)" "unprognostic (1.06e-1)" "unprognostic (5.90e-2)" "unprognostic (3.47e-2)" "unprognostic (9.02e-2)" "unprognostic (1.21e-1)" "unprognostic (7.63e-2)" "unprognostic (1.95e-1)" "unprognostic (8.53e-3)" "unprognostic (2.98e-1)" "unprognostic (2.15e-1)" "unprognostic (8.49e-2)" "unprognostic (1.11e-2)" "unprognostic (1.97e-1)" "unprognostic (1.13e-1)" "unprognostic (2.73e-2)" "unprognostic (1.54e-3)" GATAD2A p66alpha ENSG00000167491 "GATA zinc finger domain containing 2A" Q86YP4 19 19385826-19508932 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 615.8" "Cell type enhanced" "Detected in all" "leukocyte: 195.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006759, HPA024373" Enhanced Enhanced Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 44: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 64 Nucleoplasm "HPA006759: , HPA024373: " "unprognostic (1.78e-1)" "unprognostic (1.90e-1)" "unprognostic (1.29e-1)" "unprognostic (3.92e-3)" "unprognostic (9.32e-2)" "unprognostic (2.48e-1)" "unprognostic (1.10e-1)" "unprognostic (3.87e-1)" "unprognostic (7.76e-2)" "unprognostic (3.40e-2)" "potential prognostic favorable (6.38e-7)" "unprognostic (1.81e-2)" "unprognostic (2.15e-2)" "unprognostic (3.93e-2)" "unprognostic (1.96e-1)" "unprognostic (6.53e-2)" "unprognostic (2.51e-3)" "unprognostic (3.39e-2)" "unprognostic (2.27e-2)" "unprognostic (1.11e-1)" "unprognostic (1.15e-1)" "unprognostic (2.09e-3)" "unprognostic (2.64e-2)" "unprognostic (1.70e-2)" "unprognostic (2.68e-2)" "unprognostic (1.65e-3)" "unprognostic (3.26e-1)" "unprognostic (7.14e-2)" "unprognostic (3.08e-1)" "unprognostic (3.28e-2)" "unprognostic (2.93e-1)" GATAD2B P66beta ENSG00000143614 "GATA zinc finger domain containing 2B" Q8WXI9 1 153789030-153923360 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Repressor "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 288.0;Neutrophils: 338.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 4.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017015 Approved Enhanced Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 24: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 102: Non-specific - Mixed function" 102 Nucleoplasm "HPA017015: " "unprognostic (1.27e-2)" "unprognostic (2.20e-1)" "unprognostic (1.74e-1)" "unprognostic (6.14e-2)" "unprognostic (7.11e-2)" "unprognostic (1.73e-2)" "unprognostic (1.55e-2)" "unprognostic (5.76e-2)" "unprognostic (1.34e-1)" "potential prognostic unfavorable (5.33e-4)" "potential prognostic favorable (9.96e-5)" "unprognostic (2.80e-3)" "unprognostic (2.77e-1)" "unprognostic (1.22e-1)" "unprognostic (1.65e-1)" "unprognostic (1.29e-1)" "unprognostic (2.77e-2)" "unprognostic (2.40e-2)" "unprognostic (3.42e-2)" "unprognostic (2.90e-2)" "unprognostic (4.75e-1)" "unprognostic (3.78e-2)" "unprognostic (9.94e-2)" "unprognostic (1.66e-1)" "unprognostic (2.05e-1)" "unprognostic (6.18e-2)" "unprognostic (5.61e-2)" "unprognostic (3.71e-1)" "unprognostic (5.66e-2)" "unprognostic (2.66e-2)" "unprognostic (3.13e-2)" GATB "PET112, PET112L" ENSG00000059691 "Glutamyl-tRNA amidotransferase subunit B" O75879 4 151670504-151761007 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein biosynthesis" Ligase "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 7 "Müller glia: 420.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042610 Uncertain Supported Mitochondria NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 52: Non-specific - Cellular respiration" "Cluster 27: Non-specific - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 11: Muller glia cells - Retinal homeostasis" 19 Mitochondria "HPA042610: " "unprognostic (2.94e-2)" "unprognostic (1.80e-2)" "unprognostic (2.60e-2)" "unprognostic (1.21e-1)" "unprognostic (1.88e-1)" "unprognostic (2.67e-1)" "unprognostic (1.44e-2)" "unprognostic (1.17e-2)" "unprognostic (4.58e-2)" "validated prognostic favorable (3.09e-8)" "validated prognostic favorable (2.07e-5)" "unprognostic (2.47e-2)" "unprognostic (2.81e-1)" "unprognostic (2.20e-2)" "unprognostic (8.41e-2)" "unprognostic (5.51e-2)" "unprognostic (3.78e-1)" "unprognostic (2.27e-1)" "unprognostic (3.24e-1)" "unprognostic (3.87e-1)" "unprognostic (3.74e-2)" "unprognostic (9.66e-2)" "unprognostic (1.07e-3)" "unprognostic (3.14e-2)" "unprognostic (1.58e-1)" "unprognostic (2.33e-1)" "unprognostic (2.30e-1)" "unprognostic (5.50e-3)" "unprognostic (8.45e-2)" GATC "15E1.2, FLJ37000" ENSG00000257218 "Glutamyl-tRNA amidotransferase subunit C" O43716 12 120446444-120463749 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein biosynthesis" Ligase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 32: Basophils - Transcription" "Cluster 8: Pancreas - Proteolysis" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 12 "unprognostic (2.43e-1)" "unprognostic (5.35e-2)" "unprognostic (2.37e-3)" "unprognostic (1.55e-1)" "unprognostic (7.25e-2)" "unprognostic (2.55e-2)" "unprognostic (7.36e-2)" "unprognostic (1.24e-1)" "unprognostic (1.20e-1)" "unprognostic (4.32e-3)" "unprognostic (3.53e-3)" "potential prognostic favorable (5.42e-4)" "unprognostic (1.16e-1)" "validated prognostic unfavorable (8.66e-6)" "validated prognostic unfavorable (6.03e-5)" "unprognostic (5.42e-2)" "unprognostic (2.45e-1)" "unprognostic (2.98e-2)" "unprognostic (3.01e-2)" "unprognostic (2.50e-1)" "unprognostic (1.54e-3)" "unprognostic (2.35e-2)" "unprognostic (4.30e-2)" "unprognostic (1.15e-2)" "potential prognostic favorable (5.03e-4)" "unprognostic (2.34e-1)" "unprognostic (6.07e-2)" "unprognostic (2.40e-1)" "unprognostic (9.47e-2)" "unprognostic (2.15e-2)" "unprognostic (6.66e-3)" GATD1 "FLJ34283, PDDC1" ENSG00000177225 "Glutamine amidotransferase class 1 domain containing 1" Q8NB37 11 767220-777488 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008812 Uncertain Uncertain Nucleoplasm "Secreted to blood" "No annotated function" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 64: Non-specific - Transcription" "Cluster 44: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 3 Nucleoplasm "HPA008812: " "unprognostic (6.80e-3)" "unprognostic (1.90e-2)" "unprognostic (5.55e-3)" "unprognostic (1.19e-2)" "unprognostic (9.27e-2)" "unprognostic (1.57e-2)" "unprognostic (2.81e-2)" "unprognostic (7.43e-2)" "unprognostic (2.63e-3)" "unprognostic (1.29e-2)" "unprognostic (2.70e-2)" "unprognostic (1.06e-2)" "potential prognostic unfavorable (9.85e-6)" "unprognostic (4.10e-2)" "unprognostic (7.92e-2)" "unprognostic (1.92e-2)" "unprognostic (2.46e-2)" "unprognostic (6.93e-2)" "unprognostic (1.53e-1)" "unprognostic (1.25e-2)" "unprognostic (1.50e-2)" "unprognostic (1.28e-3)" "potential prognostic favorable (3.25e-4)" "unprognostic (1.38e-3)" "unprognostic (3.65e-3)" "unprognostic (1.70e-2)" "unprognostic (7.53e-2)" "unprognostic (6.01e-2)" "unprognostic (7.93e-2)" GATD3 "C21orf33, D21S2048E, ES1, GATD3A, GT335, HES1, KNP-I, KNP-Ia, KNPH, KNPI" ENSG00000160221 "Glutamine amidotransferase class 1 domain containing 3" P0DPI2 21 44133610-44210114 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 357.4" "Cell type enhanced" "Detected in many" "Breast lactating cells: 36.4;Colonocytes: 26.3;Enteric stem cells: 35.0;Enteric transient amplifying cells: 35.3;Epididymal efferent duct absorptive cells: 28.9;Kupffer cells: 28.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018517 Enhanced Approved Centrosome,Mitochondria NA NA 860000 "Cluster 13: Non-specific - Mitochondria" "Cluster 76: Non-specific - Metabolism" "Cluster 45: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 23 Mitochondria Centrosome "HPA018517: " "unprognostic (6.10e-3)" "unprognostic (8.51e-2)" "unprognostic (3.65e-2)" "unprognostic (1.47e-1)" "unprognostic (2.86e-1)" "unprognostic (9.47e-2)" "unprognostic (6.86e-2)" "unprognostic (3.52e-2)" "unprognostic (2.09e-1)" "unprognostic (1.81e-1)" "unprognostic (5.95e-2)" "unprognostic (1.63e-1)" "unprognostic (4.25e-3)" "unprognostic (3.70e-1)" "unprognostic (8.46e-2)" "unprognostic (3.09e-1)" "unprognostic (3.38e-1)" "unprognostic (2.99e-2)" "unprognostic (1.94e-1)" "unprognostic (1.87e-2)" "unprognostic (1.89e-2)" "unprognostic (3.26e-2)" "unprognostic (9.00e-2)" "unprognostic (6.43e-2)" "unprognostic (7.71e-2)" "potential prognostic unfavorable (5.53e-4)" "unprognostic (8.16e-2)" "unprognostic (3.59e-2)" "unprognostic (1.82e-1)" GATM AGAT ENSG00000171766 "Glycine amidinotransferase" P50440 15 45361124-45402327 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 12 "kidney: 1959.8;liver: 2621.4;pancreas: 2768.2" "Group enriched" "Detected in many" 5 "Granulosa cells: 630.1;Hepatocytes: 1859.5;Pancreatic acinar cells: 1024.7" "Cell type enhanced" "Detected in all" "oligodendrocyte: 227.1" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 487.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "memory B-cell: 11.1;myeloid DC: 6.6;naive B-cell: 5.4;plasmacytoid DC: 6.8" "Group enriched" "Detected in many" 5 "B-cells: 11.1;dendritic cells: 6.8" "Cancer enriched" "Detected in all" 4 "Rhabdoid: 180.4" "Adipose subcutaneous - Smooth muscle cells, Colon - Enteric glia cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Smooth muscle cells, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026077 Enhanced Supported Mitochondria NA NA 930000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 70: Non-specific - Protein processing" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 93: Hepatocytes - Bile production & excretion" 10 Mitochondria "HPA026077: " "unprognostic (6.46e-2)" "unprognostic (6.23e-2)" "unprognostic (1.94e-1)" "unprognostic (8.60e-2)" "unprognostic (1.00e-1)" "unprognostic (2.76e-1)" "unprognostic (2.05e-1)" "unprognostic (4.45e-2)" "unprognostic (6.80e-2)" "unprognostic (1.52e-1)" "validated prognostic favorable (4.33e-10)" "validated prognostic favorable (3.22e-6)" "unprognostic (2.94e-3)" "unprognostic (1.46e-2)" "unprognostic (7.87e-3)" "unprognostic (1.14e-1)" "unprognostic (4.36e-1)" "unprognostic (1.44e-1)" "unprognostic (1.21e-1)" "unprognostic (5.68e-2)" "unprognostic (2.13e-1)" "unprognostic (8.63e-2)" "unprognostic (2.05e-2)" "unprognostic (1.11e-1)" "unprognostic (2.29e-1)" "unprognostic (4.57e-2)" "unprognostic (4.13e-2)" "unprognostic (1.50e-1)" "unprognostic (2.32e-1)" "unprognostic (3.06e-2)" "unprognostic (3.98e-2)" GBA1 "GBA, GLUC" ENSG00000177628 "Glucosylceramidase beta 1" P04062 1 155234452-155244699 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Lipid metabolism, Sphingolipid metabolism, Steroid metabolism, Sterol metabolism" "Glycosidase, Glycosyltransferase, Hydrolase, Transferase" "Disease variant, Gaucher disease, Ichthyosis, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 18.0;Loop of henle epithelial cells: 11.0;Podocytes: 13.2;Proximal tubule cells: 16.4;Syncytiotrophoblasts: 19.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Fibroblasts, Colon - Macrophages, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Keratinocyte (granular), Spleen - Macrophages, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006667, CAB037171, CAB037289" Supported "Intracellular and membrane" Enzyme NA NA 530000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 27: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." 11 "CAB037171: , CAB037289: , HPA006667: " "unprognostic (1.93e-3)" "unprognostic (2.52e-2)" "unprognostic (7.87e-3)" "unprognostic (8.43e-2)" "unprognostic (1.80e-1)" "unprognostic (2.12e-1)" "unprognostic (1.22e-2)" "unprognostic (7.08e-2)" "unprognostic (3.36e-1)" "unprognostic (1.47e-1)" "potential prognostic favorable (3.03e-4)" "unprognostic (4.58e-2)" "unprognostic (4.53e-2)" "potential prognostic unfavorable (5.76e-4)" "unprognostic (1.82e-1)" "unprognostic (8.37e-2)" "unprognostic (2.77e-1)" "unprognostic (1.21e-1)" "unprognostic (1.83e-2)" "unprognostic (1.04e-1)" "unprognostic (2.41e-2)" "unprognostic (2.07e-1)" "unprognostic (8.63e-2)" "unprognostic (1.21e-1)" "potential prognostic unfavorable (6.13e-4)" "unprognostic (2.43e-2)" "unprognostic (2.20e-1)" "unprognostic (2.24e-1)" "unprognostic (1.89e-1)" "unprognostic (2.51e-1)" "unprognostic (9.99e-3)" GBA2 "AD035, DKFZp762K054, KIAA1605, SPG46" ENSG00000070610 "Glucosylceramidase beta 2" Q9HCG7 9 35736866-35749228 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Lipid metabolism, Sphingolipid metabolism, Steroid metabolism, Sterol metabolism" "Glycosidase, Glycosyltransferase, Hydrolase, Transferase" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 135.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024026 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 1: Enterocytes - Absorption and Digestion" 2 "Nucleoplasm, Golgi apparatus" Cytosol "HPA024026: " "unprognostic (4.61e-2)" "unprognostic (1.39e-1)" "unprognostic (4.25e-1)" "unprognostic (1.68e-1)" "unprognostic (2.64e-1)" "unprognostic (2.74e-2)" "unprognostic (9.32e-2)" "potential prognostic favorable (3.14e-4)" "unprognostic (3.61e-2)" "unprognostic (1.04e-1)" "validated prognostic favorable (1.37e-5)" "validated prognostic favorable (8.22e-4)" "potential prognostic favorable (5.56e-8)" "unprognostic (1.05e-2)" "unprognostic (2.95e-1)" "unprognostic (4.29e-2)" "unprognostic (1.11e-1)" "unprognostic (3.77e-1)" "unprognostic (1.26e-1)" "unprognostic (3.83e-2)" "unprognostic (1.41e-2)" "potential prognostic favorable (5.80e-4)" "unprognostic (2.31e-1)" "unprognostic (9.55e-3)" "unprognostic (3.69e-1)" "unprognostic (2.10e-1)" "unprognostic (4.58e-2)" "unprognostic (7.73e-2)" "unprognostic (2.53e-1)" "unprognostic (1.40e-2)" "unprognostic (2.22e-1)" GBA3 "CBGL1, GLUC, KLrP" ENSG00000249948 "Glucosylceramidase beta 3 (gene/pseudogene)" 4 22692914-22819575 "Metabolic proteins, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 16 "intestine: 161.4;kidney: 166.9;liver: 211.1" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 157.6;Endometrial glandular cells: 71.1;Endometrial luminal cells: 157.5;Enteric transient amplifying cells: 75.1;Enterocytes: 525.9;Epididymal efferent duct absorptive cells: 57.5;Fallopian tube ciliated cells: 61.1;Hepatocytes: 117.1;Paneth cells: 58.0;Tuft cells: 57.6" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 11.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 1.1;lymphoma: 1.6" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Alveolar cells type 1, Minor Salivary Gland - Plasma cells" "Low region specificity" "Detected in all" NA NA "Cluster 76: Non-specific - Metabolism" "Cluster 59: Leukemia - T-cell receptor" "Cluster 1: Enterocytes - Absorption and Digestion" GBE1 ENSG00000114480 "1,4-alpha-glucan branching enzyme 1" Q04446 3 81489703-81761645 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycogen biosynthesis" "Glycosyltransferase, Transferase" "Disease variant, Glycogen storage disease, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 141.9" "Cell type enhanced" "Detected in many" "Adipocytes: 1160.0;Cardiomyocytes: 621.0;Myonuclei: 1502.9;Neutrophil progenitors: 886.8;Neutrophils: 638.0;Thymic myoid cells: 1079.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038073, HPA038074, HPA038075" Enhanced Approved Cytosol NA NA 7700000 "Cluster 25: Non-specific - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 1 Cytosol "HPA038073: , HPA038074: , HPA038075: " "unprognostic (2.49e-1)" "unprognostic (1.69e-1)" "unprognostic (3.05e-2)" "unprognostic (6.10e-3)" "unprognostic (4.44e-1)" "unprognostic (2.54e-1)" "unprognostic (4.38e-2)" "unprognostic (2.16e-2)" "unprognostic (1.23e-1)" "potential prognostic unfavorable (3.33e-5)" "unprognostic (5.56e-3)" "unprognostic (3.73e-2)" "unprognostic (1.33e-1)" "unprognostic (1.18e-3)" "unprognostic (2.42e-3)" "validated prognostic unfavorable (4.78e-7)" "validated prognostic unfavorable (5.21e-4)" "unprognostic (3.29e-1)" "unprognostic (8.42e-2)" "unprognostic (1.11e-1)" "unprognostic (2.36e-3)" "unprognostic (3.15e-2)" "unprognostic (2.66e-2)" "unprognostic (1.02e-1)" "unprognostic (1.99e-1)" "unprognostic (5.77e-3)" "unprognostic (3.08e-1)" "unprognostic (6.26e-2)" "unprognostic (1.59e-1)" "unprognostic (8.75e-3)" "unprognostic (2.59e-2)" GBF1 "ARF1GEF, KIAA0248" ENSG00000107862 "Golgi brefeldin A resistant guanine nucleotide exchange factor 1" Q92538 10 102245371-102382899 "Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Protein transport, Transport" "Guanine-nucleotide releasing factor" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Myonuclei: 550.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 28.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037759, HPA037760" Uncertain Supported "Golgi apparatus" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 103: Non-specific - Basic cellular processes" 58 "Golgi apparatus" "HPA037759: , HPA037760: " "unprognostic (5.96e-2)" "unprognostic (8.70e-2)" "unprognostic (1.44e-1)" "unprognostic (6.72e-3)" "unprognostic (1.26e-1)" "unprognostic (7.60e-3)" "unprognostic (3.87e-1)" "potential prognostic favorable (1.64e-4)" "unprognostic (2.12e-1)" "unprognostic (1.11e-1)" "unprognostic (1.29e-1)" "unprognostic (7.26e-3)" "unprognostic (9.60e-2)" "unprognostic (1.12e-3)" "unprognostic (1.01e-1)" "potential prognostic unfavorable (9.56e-4)" "unprognostic (5.61e-3)" "potential prognostic favorable (7.44e-4)" "unprognostic (9.86e-2)" "unprognostic (4.04e-2)" "unprognostic (9.51e-3)" "unprognostic (3.49e-2)" "unprognostic (1.11e-2)" "unprognostic (3.06e-1)" "unprognostic (2.92e-2)" "unprognostic (1.52e-2)" "unprognostic (3.03e-2)" "unprognostic (7.10e-2)" "unprognostic (3.31e-2)" "unprognostic (9.05e-2)" "unprognostic (6.99e-2)" GBGT1 "A3GALNT, FS, MGC44848, UDP-GalNAc" ENSG00000148288 "Globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 (FORS blood group)" Q8N5D6 9 133152948-133163933 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 5.1;Bergmann glia: 3.9;Brain excitatory neurons: 3.2;Brain inhibitory neurons: 2.6;Choroid plexus epithelial cells: 7.6;Ependymal cells: 3.2;Microglia: 16.4;Oligodendrocyte progenitor cells: 2.8;Other brain neurons: 4.0" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 22.3;pericyte: 30.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in many" 8 "Leukemia: 27.2" "Adipose subcutaneous - Macrophages, Skeletal muscle - Macrophages, Stomach - Parietal cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051298 Approved "Intracellular and membrane" Enzyme NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 44: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 22: Non-specific - Basic cellular functions" "HPA051298: " "unprognostic (2.57e-2)" "unprognostic (1.41e-2)" "unprognostic (4.42e-2)" "unprognostic (4.28e-2)" "unprognostic (2.45e-2)" "unprognostic (2.21e-1)" "unprognostic (4.82e-3)" "unprognostic (2.64e-1)" "unprognostic (1.63e-1)" "unprognostic (2.90e-1)" "unprognostic (1.49e-2)" "unprognostic (3.87e-1)" "unprognostic (4.50e-2)" "unprognostic (9.78e-3)" "unprognostic (2.22e-1)" "unprognostic (1.02e-2)" "unprognostic (6.03e-2)" "unprognostic (5.99e-2)" "unprognostic (1.49e-1)" "unprognostic (1.63e-3)" "unprognostic (2.18e-1)" "unprognostic (2.76e-1)" "unprognostic (4.15e-2)" "unprognostic (4.18e-1)" "unprognostic (1.12e-1)" "unprognostic (4.05e-2)" "unprognostic (1.56e-1)" "unprognostic (3.28e-2)" "unprognostic (3.97e-2)" "unprognostic (2.48e-1)" "unprognostic (4.52e-2)" GBP1 ENSG00000117228 "Guanylate binding protein 1" P32455 1 89051882-89065360 "Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 82.4;lymphoid tissue: 67.5" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 199.5;Epididymal basal cells: 753.5;Epididymal efferent duct ciliated cells: 290.0;Migrating cytotrophoblasts: 145.1;Pancreatic duct cells: 111.7" "Cell type enhanced" "Detected in some" "endothelial cell: 42.7;ependymal cell: 26.5;leukocyte: 25.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Lung - NK-cells (Lung), Prostate - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" CAB015450 Approved "Intracellular and membrane" Immunity NA NA 130000 "Cluster 33: Non-specific - ATP binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 13 "CAB015450: " "unprognostic (3.18e-1)" "unprognostic (3.71e-2)" "unprognostic (1.53e-1)" "unprognostic (8.27e-2)" "unprognostic (2.40e-2)" "unprognostic (9.93e-2)" "unprognostic (3.10e-1)" "unprognostic (1.17e-1)" "unprognostic (7.01e-2)" "unprognostic (1.32e-2)" "unprognostic (3.97e-2)" "unprognostic (6.03e-2)" "potential prognostic unfavorable (1.04e-5)" "unprognostic (6.01e-2)" "potential prognostic favorable (2.41e-4)" "unprognostic (6.08e-2)" "unprognostic (4.01e-2)" "unprognostic (3.46e-1)" "unprognostic (5.50e-2)" "unprognostic (3.58e-2)" "potential prognostic favorable (2.69e-6)" "unprognostic (1.26e-2)" "unprognostic (2.38e-2)" "unprognostic (9.76e-2)" "unprognostic (1.24e-2)" "unprognostic (5.41e-3)" "unprognostic (1.11e-1)" "unprognostic (1.84e-2)" "unprognostic (4.50e-2)" "unprognostic (7.29e-3)" "unprognostic (1.45e-1)" GBP2 ENSG00000162645 "Guanylate binding protein 2" P32456 1 89106132-89150456 "Predicted intracellular proteins" "Immunity, Innate immunity" "Antimicrobial, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast secretory cells: 212.7;Endometrial luminal cells: 316.1;Epididymal basal cells: 285.0;monocytes: 296.5;Neutrophils: 831.5" "Group enriched" "Detected in many" 5 "endothelial cell: 84.4;fibroblast: 34.4;leukocyte: 127.8;vascular associated smooth muscle cell: 44.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Prostate - Fibroblasts, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA042682, CAB045975" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 12: Non-specific - Vasculature" "Cluster 59: Leukemia - T-cell receptor" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 9 "Nucleoplasm, Cytosol" "CAB045975: , HPA042682: " "unprognostic (3.04e-2)" "unprognostic (2.15e-3)" "unprognostic (4.65e-2)" "unprognostic (2.41e-1)" "unprognostic (7.95e-2)" "unprognostic (8.36e-2)" "unprognostic (1.17e-1)" "unprognostic (1.94e-2)" "unprognostic (1.66e-1)" "unprognostic (2.23e-1)" "unprognostic (7.49e-2)" "unprognostic (1.69e-3)" "unprognostic (1.65e-3)" "unprognostic (1.60e-1)" "unprognostic (1.01e-1)" "unprognostic (2.47e-2)" "unprognostic (9.14e-3)" "unprognostic (1.84e-1)" "unprognostic (1.72e-1)" "unprognostic (2.54e-2)" "unprognostic (2.24e-2)" "unprognostic (1.44e-3)" "unprognostic (1.41e-1)" "unprognostic (1.05e-1)" "unprognostic (1.35e-2)" "unprognostic (3.10e-2)" "unprognostic (2.93e-2)" "unprognostic (8.72e-2)" "unprognostic (5.09e-2)" "unprognostic (7.18e-3)" "unprognostic (5.88e-3)" GBP3 FLJ10961 ENSG00000117226 "Guanylate binding protein 3" Q9H0R5 1 89006679-89022894 "Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 74.1" "Cell type enhanced" "Detected in many" "Colonocytes: 85.7;Enterocytes: 128.4;Epididymal basal cells: 96.4;Epididymal efferent duct ciliated cells: 67.6;Foveolar cells: 79.0;Salivary duct cells: 90.0;Urothelial cells: 73.4" "Cell type enhanced" "Detected in some" "endothelial cell: 32.2;leukocyte: 39.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" HPA045657 Approved NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 77: Intestine - Digestion" "Cluster 39: Astrocytes - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 10 "HPA045657: " "unprognostic (2.17e-1)" "unprognostic (2.70e-2)" "unprognostic (2.88e-1)" "unprognostic (1.12e-1)" "unprognostic (1.06e-1)" "unprognostic (1.07e-1)" "unprognostic (4.75e-2)" "unprognostic (5.75e-2)" "unprognostic (1.87e-2)" "unprognostic (2.81e-2)" "unprognostic (2.84e-3)" "unprognostic (1.05e-1)" "unprognostic (1.72e-2)" "unprognostic (4.56e-2)" "unprognostic (4.04e-3)" "unprognostic (1.14e-1)" "unprognostic (5.11e-2)" "unprognostic (4.33e-3)" "unprognostic (1.22e-1)" "unprognostic (3.66e-1)" "unprognostic (2.15e-2)" "unprognostic (5.94e-2)" "unprognostic (2.23e-1)" "unprognostic (3.03e-1)" "unprognostic (3.73e-1)" "unprognostic (7.41e-2)" "unprognostic (2.77e-1)" "unprognostic (7.91e-2)" "unprognostic (2.12e-2)" "unprognostic (8.25e-2)" "unprognostic (2.48e-1)" GBP4 Mpa2 ENSG00000162654 "Guanylate binding protein 4" Q96PP9 1 89181144-89198942 "Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 41.5;Foveolar cells: 26.6;Hematopoietic stem cells: 55.8;Kupffer cells: 37.9;NK-cells: 41.2;Vascular endothelial cells: 83.1" "Cell type enriched" "Detected in some" 4 "endothelial cell: 139.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 12.7" "Breast - Endothelial cells" "HPA030101, HPA062039" Enhanced Supported "Golgi apparatus,Plasma membrane" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 3 "Golgi apparatus" "Plasma membrane" "HPA030101: , HPA062039: " "unprognostic (4.16e-2)" "unprognostic (2.36e-2)" "unprognostic (1.10e-1)" "unprognostic (1.56e-1)" "unprognostic (1.04e-1)" "unprognostic (2.01e-1)" "unprognostic (5.39e-1)" "unprognostic (4.18e-2)" "unprognostic (2.24e-3)" "unprognostic (1.05e-1)" "validated prognostic favorable (1.39e-4)" "validated prognostic favorable (2.87e-4)" "unprognostic (6.70e-3)" "unprognostic (1.49e-1)" "unprognostic (1.32e-3)" "unprognostic (1.34e-1)" "unprognostic (3.47e-1)" "unprognostic (2.64e-1)" "unprognostic (3.71e-1)" "unprognostic (6.25e-3)" "potential prognostic favorable (1.43e-4)" "unprognostic (3.82e-3)" "unprognostic (5.61e-1)" "unprognostic (1.65e-1)" "unprognostic (2.61e-2)" "unprognostic (2.19e-2)" "unprognostic (1.35e-1)" "unprognostic (1.04e-1)" "unprognostic (6.44e-2)" "unprognostic (2.97e-2)" "unprognostic (1.32e-1)" GBP5 ENSG00000154451 "Guanylate binding protein 5" Q96PP8 1 89256189-89272860 "Predicted intracellular proteins" "Immunity, Inflammatory response, Innate immunity" "Antimicrobial, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.1;lymphoid tissue: 40.5" "Cell type enhanced" "Detected in some" "Innate lymphoid cells: 39.7;Kupffer cells: 45.1;Macrophages: 14.7;monocytes: 25.2;Neutrophils: 42.4;NK-cells: 97.3;T-cells: 78.1" "Cell type enriched" "Detected in some" 18 "leukocyte: 74.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 97.5" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 6.9" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Minor Salivary Gland - T-cells, Pancreas - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Testis - Spermatogonia, Thyroid gland - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA028656 Supported NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 8: Immune cells - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 6 "HPA028656: " "unprognostic (8.01e-2)" "unprognostic (5.73e-2)" "unprognostic (8.05e-2)" "unprognostic (7.24e-2)" "unprognostic (8.97e-2)" "unprognostic (2.49e-1)" "unprognostic (2.89e-2)" "unprognostic (9.53e-2)" "unprognostic (2.68e-2)" "unprognostic (1.34e-1)" "unprognostic (4.96e-2)" "unprognostic (1.54e-1)" "unprognostic (3.33e-3)" "unprognostic (1.89e-1)" "unprognostic (5.44e-2)" "unprognostic (1.78e-2)" "unprognostic (3.58e-1)" "unprognostic (5.72e-2)" "unprognostic (2.66e-1)" "unprognostic (1.19e-3)" "unprognostic (2.03e-2)" "unprognostic (1.99e-2)" "unprognostic (1.92e-1)" "unprognostic (2.62e-1)" "unprognostic (3.90e-2)" "unprognostic (9.21e-2)" "unprognostic (3.09e-2)" "unprognostic (1.79e-2)" "unprognostic (5.29e-2)" "unprognostic (1.40e-1)" "unprognostic (2.20e-1)" GBP6 DKFZp686G0786 ENSG00000183347 "Guanylate binding protein family member 6" Q6ZN66 1 89364059-89388160 "Predicted intracellular proteins" "Immunity, Innate immunity" "Antimicrobial, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "esophagus: 276.3" "Group enriched" "Detected in some" 5 "Esophageal apical cells: 1159.1;Esophageal basal cells: 474.7;Esophageal suprabasal cells: 1774.8;Suprabasal keratinocytes: 976.9" "Cell type enhanced" "Detected in some" "endothelial cell: 3.6" "Group enriched" "Detected in many" 5 "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 27.3;Head and Neck Squamous Cell Carcinoma (TCGA): 40.9;Lung Squamous Cell Carcinoma (TCGA): 30.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Esophageal cancer: 13.5;Gallbladder cancer: 16.3;head and neck cancer: 8.8" "Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary gland basal cells" "Low region specificity" "Detected in single" HPA027744 Enhanced NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 1 "HPA027744: " "unprognostic (3.63e-1)" "unprognostic (3.85e-2)" "unprognostic (1.92e-1)" "unprognostic (5.19e-2)" "unprognostic (2.08e-2)" "unprognostic (2.01e-1)" "unprognostic (3.52e-2)" "unprognostic (7.93e-3)" "unprognostic (4.65e-2)" "unprognostic (7.79e-2)" "unprognostic (3.28e-2)" "unprognostic (2.35e-1)" GBP7 "FLJ38822, GBP4L" ENSG00000213512 "Guanylate binding protein 7" Q8N8V2 1 89131742-89176009 "Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" "Antimicrobial, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 152 "liver: 93.7" "Cell type enhanced" "Detected in some" "Astrocytes: 1.8;Bergmann glia: 3.9;Hepatocytes: 11.3;Müller glia: 1.3;Myonuclei: 5.1;Myosatellite cells: 2.4;Schwann cells: 2.1;Thymic myoid cells: 2.7" "Cell type enhanced" "Detected in some" "Bergmann glia: 7.7" "Cancer enriched" "Detected in single" 40 "Liver Hepatocellular Carcinoma (TCGA): 16.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes" HPA051245 Uncertain NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 51: Neurons - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 2 "HPA051245: " "unprognostic (2.61e-3)" "potential prognostic favorable (1.78e-6)" GBX1 ENSG00000164900 "Gastrulation brain homeobox 1" Q14549 7 151148009-151174745 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "skeletal muscle: 10.6;testis: 7.6" "Group enriched" "Detected in some" 7 "Early primary spermatocytes: 134.6;Myonuclei: 289.8" "Group enriched" "Detected in some" 4 "eccentric medium spiny neuron: 2.1;fibroblast: 2.5;splatter: 3.3" "Cancer enhanced" "Detected in single" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 1.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skeletal muscle - Skeletal myocytes, Testis - Early spermatids" "Region enhanced" "Detected in some" "basal ganglia: 3.3" "Low region specificity" "Detected in single" HPA055783 Approved NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 43: Hindbrain - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" "HPA055783: " "unprognostic (6.42e-2)" GBX2 ENSG00000168505 "Gastrulation brain homeobox 2" P52951 2 236165236-236168386 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 12 "brain: 2.6" "Cell type enhanced" "Detected in some" "Bergmann glia: 4.1;Early spermatids: 3.6;Ependymal cells: 2.2;Other brain neurons: 2.7;Undifferentiated spermatogonia: 1.1" "Cell type enhanced" "Detected in some" "Bergmann glia: 5.9;ependymal cell: 3.6;thalamic excitatory: 13.9" "Group enriched" "Detected in some" 8 "Glioblastoma Multiforme (TCGA): 2.7;Testicular Germ Cell Tumor (TCGA): 10.6" "Region enhanced" "Detected in many" "thalamus: 31.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 11.1" "Region enhanced" "Detected in single" "thalamus: 1.3" "Group enriched" "Detected in some" 4 "midbrain: 3.3;pons: 3.5;thalamus: 8.2" HPA067809 Approved Nucleoplasm Yes NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 38: Sub-cortical - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 108: Fibroblasts - ECM organization" Nucleoplasm "HPA067809: " "unprognostic (9.29e-3)" "unprognostic (1.21e-2)" "unprognostic (3.79e-2)" GC "DBP, hDBP, VDBP" ENSG00000145321 "GC vitamin D binding protein" P02774 4 71741696-71804041 "Metabolic proteins, Plasma proteins, Predicted secreted proteins" Transport Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "liver: 7722.0" "Cell type enhanced" "Detected in some" "Cholangiocytes: 1567.9;Hepatocytes: 2860.9;Pancreatic islet cells: 617.9" "Cell type enriched" "Detected in some" 4 "ependymal cell: 8.5" "Cancer enriched" "Detected in many" 15 "Liver Hepatocellular Carcinoma (TCGA): 1758.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 17 "liver cancer: 29.9" "Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001526, CAB008596, HPA019855" Supported "Secreted to blood" Transport NA NA 143000000000 110000000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 18: Liver cancer - Metabolism" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" "CAB008596: , HPA001526: , HPA019855: " "unprognostic (8.84e-2)" "unprognostic (2.29e-2)" "unprognostic (2.40e-3)" "potential prognostic favorable (8.66e-4)" "unprognostic (9.97e-2)" "unprognostic (2.09e-3)" "unprognostic (1.43e-3)" "potential prognostic unfavorable (9.90e-4)" "unprognostic (2.22e-2)" GCA GCL ENSG00000115271 Grancalcin P28676 2 162318840-162371595 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "bone marrow: 307.8" "Group enriched" "Detected in many" 9 "Neutrophil progenitors: 2176.9;Neutrophils: 3493.5" "Cell type enhanced" "Detected in all" "oligodendrocyte: 122.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "eosinophil: 328.1;neutrophil: 867.8" "Lineage enriched" "Detected in all" 7 "granulocytes: 867.8" "Low cancer specificity" "Detected in all" "Liver - Neutrophils, Lung - Neutrophils_2, Skeletal muscle - Endothelial cells, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035033, HPA035034" Enhanced Supported "Plasma membrane,Cytosol" NA NA 100000 "Cluster 21: Neutrophils - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 30: White matter - Myelination" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 14 Cytosol "Plasma membrane" "HPA035033: , HPA035034: " "unprognostic (1.76e-1)" "unprognostic (1.52e-1)" "unprognostic (1.14e-1)" "unprognostic (1.09e-1)" "unprognostic (1.09e-1)" "unprognostic (1.17e-1)" "unprognostic (5.01e-2)" "unprognostic (3.55e-1)" "unprognostic (1.66e-1)" "unprognostic (8.31e-2)" "potential prognostic favorable (2.51e-5)" "unprognostic (1.13e-1)" "unprognostic (7.86e-2)" "potential prognostic unfavorable (7.81e-4)" "unprognostic (1.04e-2)" "unprognostic (4.96e-2)" "unprognostic (8.25e-2)" "unprognostic (1.31e-2)" "unprognostic (2.34e-1)" "unprognostic (1.04e-2)" "unprognostic (4.80e-2)" "unprognostic (1.18e-1)" "unprognostic (1.31e-1)" "unprognostic (1.83e-1)" "unprognostic (3.87e-2)" "unprognostic (3.21e-2)" "unprognostic (1.46e-1)" "unprognostic (1.34e-1)" "unprognostic (2.71e-1)" "unprognostic (9.48e-3)" "unprognostic (1.08e-1)" GCAT KBL ENSG00000100116 "Glycine C-acetyltransferase" O75600 22 37807905-37817176 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 132.2" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 151.3;Hepatocytes: 74.3;Oocytes: 211.8;Pancreatic acinar cells: 74.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Prostate - Prostate glandular cells, Skin - Inner root sheath cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020460, HPA063924" Approved Supported "Nucleoplasm,Nuclear speckles,Mitochondria" Yes No "Cluster 11: T-cells - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 45: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 84: Apical squamous epithelium - Cornification" 21 "Nuclear speckles" "Nucleoplasm, Mitochondria" "HPA020460: , HPA063924: " "unprognostic (2.65e-1)" "unprognostic (3.36e-1)" "potential prognostic unfavorable (3.15e-4)" "unprognostic (2.69e-1)" "unprognostic (6.21e-2)" "unprognostic (1.75e-1)" "unprognostic (4.76e-2)" "unprognostic (4.14e-2)" "unprognostic (2.60e-2)" "unprognostic (4.20e-3)" "unprognostic (3.46e-2)" "unprognostic (3.01e-2)" "potential prognostic favorable (3.20e-4)" "unprognostic (1.94e-1)" "unprognostic (1.77e-1)" "unprognostic (1.20e-1)" "unprognostic (7.76e-2)" "unprognostic (5.52e-3)" "unprognostic (1.50e-1)" "unprognostic (2.25e-2)" "unprognostic (2.88e-1)" "unprognostic (3.28e-1)" "unprognostic (2.22e-1)" "unprognostic (2.77e-1)" "unprognostic (1.93e-3)" "unprognostic (1.45e-1)" "unprognostic (2.35e-2)" "unprognostic (2.12e-1)" "unprognostic (1.99e-1)" "unprognostic (8.03e-3)" "unprognostic (2.57e-1)" GCC1 "FLJ22035, GCC1P, GCC88, MGC20706" ENSG00000179562 "GRIP and coiled-coil domain containing 1" Q96CN9 7 127580628-127593611 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Cardiomyocytes: 105.5;Early spermatids: 164.2;Epicardial cells: 113.7;Late spermatids: 178.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019369, HPA021323" Enhanced Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 39: Testis - Nuclear processes" "Cluster 25: Non-specific - Transcription" "Cluster 39: Non-specific - Transcription" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 43 "Golgi apparatus" "Plasma membrane, Cytosol" "HPA019369: , HPA021323: " "unprognostic (2.02e-2)" "unprognostic (3.47e-2)" "unprognostic (2.71e-1)" "unprognostic (2.69e-2)" "unprognostic (5.67e-2)" "unprognostic (2.27e-1)" "unprognostic (2.16e-1)" "unprognostic (1.20e-1)" "unprognostic (4.96e-3)" "unprognostic (7.92e-3)" "potential prognostic favorable (3.00e-6)" "unprognostic (2.81e-2)" "unprognostic (4.44e-2)" "unprognostic (9.03e-2)" "unprognostic (2.82e-2)" "unprognostic (1.15e-1)" "unprognostic (2.56e-2)" "unprognostic (2.65e-1)" "unprognostic (4.26e-3)" "unprognostic (9.52e-3)" "unprognostic (3.66e-1)" "unprognostic (2.87e-1)" "unprognostic (7.65e-3)" "unprognostic (1.79e-3)" "unprognostic (2.18e-2)" "unprognostic (5.35e-2)" "unprognostic (1.90e-1)" "unprognostic (9.75e-3)" "unprognostic (2.81e-1)" "unprognostic (5.14e-2)" "unprognostic (2.04e-2)" GCC2 "GCC185, KIAA0336" ENSG00000135968 "GRIP and coiled-coil domain containing 2" Q8IWJ2 2 108449107-108509415 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epididymal principal cells: 584.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035849, HPA035850" Enhanced Enhanced "Nucleoplasm,Golgi apparatus" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 22: Epididymis - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 9: T-cells - Adaptive immunity: Regulation" 11 "Golgi apparatus" Nucleoplasm "HPA035849: , HPA035850: " "unprognostic (1.31e-1)" "unprognostic (7.70e-2)" "unprognostic (3.54e-1)" "unprognostic (3.79e-2)" "unprognostic (1.37e-1)" "potential prognostic favorable (6.20e-4)" "unprognostic (1.95e-1)" "unprognostic (2.40e-1)" "unprognostic (1.94e-1)" "unprognostic (2.54e-2)" "potential prognostic favorable (5.72e-6)" "unprognostic (1.16e-3)" "unprognostic (2.23e-1)" "unprognostic (8.53e-2)" "unprognostic (3.36e-1)" "unprognostic (1.20e-1)" "unprognostic (1.08e-1)" "unprognostic (1.06e-1)" "unprognostic (8.33e-2)" "unprognostic (1.85e-1)" "unprognostic (8.39e-2)" "unprognostic (1.13e-2)" "unprognostic (4.04e-2)" "unprognostic (3.15e-1)" "unprognostic (3.36e-3)" "unprognostic (1.43e-2)" "unprognostic (2.11e-1)" "unprognostic (1.88e-1)" "unprognostic (4.18e-1)" "unprognostic (5.81e-3)" "unprognostic (1.15e-1)" GCDH "ACAD5, GCD" ENSG00000105607 "Glutaryl-CoA dehydrogenase" Q92947 19 12891160-12914207 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant, Glutaricaciduria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 86.6" "Cell type enhanced" "Detected in many" "Breast lactating cells: 74.1;Hepatocytes: 153.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043252, HPA048492" Enhanced Supported Mitochondria NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 53: Liver - Plasma proteins" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 6 Mitochondria "HPA043252: , HPA048492: " "unprognostic (1.27e-1)" "unprognostic (1.68e-1)" "unprognostic (2.15e-2)" "unprognostic (1.19e-1)" "unprognostic (3.15e-2)" "unprognostic (1.69e-2)" "unprognostic (6.58e-2)" "unprognostic (3.78e-2)" "unprognostic (1.41e-1)" "unprognostic (4.06e-2)" "potential prognostic favorable (1.42e-4)" "unprognostic (1.20e-1)" "potential prognostic favorable (5.61e-8)" "unprognostic (1.17e-3)" "unprognostic (1.87e-1)" "unprognostic (1.06e-3)" "unprognostic (2.74e-1)" "unprognostic (6.08e-3)" "unprognostic (1.71e-1)" "unprognostic (1.39e-2)" "unprognostic (2.63e-1)" "unprognostic (8.30e-2)" "unprognostic (1.78e-1)" "unprognostic (9.31e-2)" "unprognostic (4.32e-3)" "unprognostic (8.75e-3)" "unprognostic (7.21e-2)" "unprognostic (4.62e-2)" "unprognostic (3.04e-1)" "unprognostic (6.58e-2)" "unprognostic (6.15e-2)" GCFC2 "C2orf3, DNABF, GCF, TCF9" ENSG00000005436 "GC-rich sequence DNA-binding factor 2" P16383 2 75652000-75710985 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 216.6;Myonuclei: 474.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077882 Approved Supported Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 6 Nucleoplasm "HPA077882: " "unprognostic (3.73e-3)" "unprognostic (1.01e-1)" "unprognostic (3.45e-2)" "unprognostic (2.34e-1)" "unprognostic (1.79e-1)" "unprognostic (5.23e-2)" "unprognostic (7.19e-3)" "unprognostic (1.35e-1)" "unprognostic (1.26e-2)" "unprognostic (5.18e-2)" "unprognostic (8.39e-2)" "unprognostic (2.69e-1)" "unprognostic (7.04e-3)" "unprognostic (5.01e-2)" "unprognostic (1.43e-2)" "unprognostic (3.76e-3)" "unprognostic (2.45e-1)" "unprognostic (2.53e-2)" "unprognostic (2.30e-1)" "unprognostic (3.88e-3)" "unprognostic (4.07e-3)" "unprognostic (4.61e-1)" "unprognostic (5.92e-2)" "unprognostic (2.44e-1)" "unprognostic (2.02e-3)" "unprognostic (1.04e-1)" "unprognostic (3.87e-1)" "unprognostic (1.57e-3)" "unprognostic (1.30e-1)" GCG "GLP-1, GLP1, GLP2, GRPP" ENSG00000115263 Glucagon P01275 2 162142882-162152404 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "pancreas: 1834.3" "Cell type enriched" "Detected in some" 19 "Pancreatic islet cells: 80427.5" "Cell type enriched" "Detected in single" 10 "midbrain-derived inhibitory: 1.7" "Cancer enriched" "Detected in some" 167 "Pancreatic Adenocarcinoma (TCGA): 1477.8" "Region enriched" "Detected in single" 51 "medulla oblongata: 13.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 114.8;Rhabdoid: 411.9" "Colon - Colon enterocytes, Pancreas - Alpha cells" "Region enriched" "Detected in single" 10 "pons and medulla: 3.5" "Region enriched" "Detected in some" 5 "spinal cord: 18.2" "CAB000040, HPA036760, HPA036761" Enhanced Approved "Endoplasmic reticulum,Vesicles" "Secreted to blood" Hormone NA NA 127000 130000 "Cluster 8: Pancreas - Proteolysis" "Cluster 43: Hindbrain - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 10 "Endoplasmic reticulum" Vesicles "CAB000040: , HPA036760: , HPA036761: " "unprognostic (8.67e-2)" "unprognostic (1.82e-1)" "unprognostic (6.19e-2)" "unprognostic (3.55e-1)" "unprognostic (2.19e-1)" "unprognostic (3.71e-3)" "unprognostic (2.83e-2)" GCGR GGR ENSG00000215644 "Glucagon receptor" P47871 17 81804132-81814008 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Diabetes mellitus, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 18 "kidney: 49.3;liver: 167.2" "Group enriched" "Detected in some" 5 "Distal convoluted tubule cells: 55.3;Loop of henle epithelial cells: 25.2;Renal collecting duct intercalated cells: 38.6;Renal connecting tubule cells: 28.7" "Cell type enhanced" "Detected in some" "fibroblast: 1.5;mammillary body: 1.5" "Group enriched" "Detected in some" 13 "Kidney Chromophobe (TCGA): 28.3;Liver Hepatocellular Carcinoma (TCGA): 9.9" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adrenal gland - Adrenal medulla cells, Pancreas - Beta cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA071228 Uncertain "Golgi apparatus" NA NA "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 19: Astrocytes - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" "Golgi apparatus" "HPA071228: " "unprognostic (3.92e-3)" "unprognostic (2.24e-1)" "unprognostic (3.85e-2)" "potential prognostic favorable (1.25e-4)" "unprognostic (1.39e-1)" "unprognostic (5.53e-2)" "unprognostic (4.87e-3)" GCH1 "DYT14, DYT5, DYT5a, GCH, GTPCH1" ENSG00000131979 "GTP cyclohydrolase 1" P30793 14 54842008-54902826 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Tetrahydrobiopterin biosynthesis" "Allosteric enzyme, Hydrolase" "Disease variant, Dystonia, Parkinsonism, Phenylketonuria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 29.6;liver: 58.1" "Cell type enhanced" "Detected in many" "monocytes: 410.4;Neuroendocrine cells: 317.9;Neutrophils: 700.2;Pancreatic islet cells: 241.8" "Cell type enhanced" "Detected in all" "endothelial cell: 79.9;leukocyte: 80.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 11.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal medulla cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA028612 Approved Supported "Nucleoplasm,Nuclear membrane,Cytosol" No No "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 11 Nucleoplasm "Nuclear membrane, Cytosol" "HPA028612: " "unprognostic (6.17e-2)" "unprognostic (1.98e-2)" "unprognostic (1.01e-1)" "unprognostic (7.30e-3)" "unprognostic (1.28e-2)" "potential prognostic unfavorable (4.52e-4)" "unprognostic (1.76e-1)" "unprognostic (3.60e-2)" "unprognostic (2.66e-1)" "unprognostic (3.16e-2)" "unprognostic (3.89e-1)" "unprognostic (1.12e-1)" "unprognostic (1.74e-2)" "unprognostic (1.51e-2)" "unprognostic (8.02e-2)" "unprognostic (5.27e-2)" "unprognostic (1.33e-1)" "unprognostic (8.43e-2)" "unprognostic (2.22e-2)" "unprognostic (1.55e-2)" "unprognostic (7.04e-2)" "potential prognostic favorable (1.82e-5)" "unprognostic (1.66e-1)" "unprognostic (2.06e-1)" "unprognostic (1.20e-1)" "unprognostic (9.51e-2)" "unprognostic (3.34e-1)" "unprognostic (4.96e-3)" "unprognostic (1.89e-3)" "unprognostic (5.99e-3)" "unprognostic (7.14e-2)" GCHFR "GFRP, HsT16933" ENSG00000137880 "GTP cyclohydrolase I feedback regulator" P30047 15 40764068-40767708 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 365.5" "Cell type enhanced" "Detected in many" "Breast lactating cells: 255.8;Enterocytes: 552.7;Epididymal efferent duct absorptive cells: 297.2;Esophageal apical cells: 1796.0;Hepatocytes: 918.7" "Cell type enhanced" "Detected in many" "leukocyte: 19.5;lower rhombic lip: 20.7" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "midbrain: 127.4" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Macrophages" "Group enriched" "Detected in many" 5 "cerebellum: 10.3;midbrain: 11.8;pons and medulla: 9.4" HPA046258 Enhanced Supported Nucleoplasm NA NA 180000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 84: Apical squamous epithelium - Cornification" Nucleoplasm "HPA046258: " "unprognostic (2.31e-2)" "unprognostic (4.81e-1)" "unprognostic (2.48e-2)" "unprognostic (3.29e-2)" "unprognostic (2.64e-1)" "unprognostic (1.75e-2)" "unprognostic (4.13e-3)" "unprognostic (1.60e-2)" "unprognostic (5.39e-3)" "potential prognostic unfavorable (5.41e-5)" "potential prognostic favorable (1.36e-5)" "unprognostic (8.42e-2)" "unprognostic (7.22e-3)" "unprognostic (2.76e-1)" "unprognostic (1.15e-2)" "unprognostic (5.55e-2)" "unprognostic (2.11e-1)" "unprognostic (2.39e-2)" "unprognostic (2.92e-1)" "unprognostic (1.73e-1)" "unprognostic (1.11e-1)" "unprognostic (2.74e-1)" "unprognostic (2.20e-1)" "unprognostic (1.29e-1)" "unprognostic (3.37e-1)" "unprognostic (1.03e-1)" "unprognostic (2.21e-1)" "unprognostic (5.43e-3)" "unprognostic (2.80e-1)" "unprognostic (2.04e-1)" "unprognostic (1.39e-2)" GCK "HK4, MODY2" ENSG00000106633 Glucokinase P35557 7 44143213-44198170 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.4;liver: 16.7;pituitary gland: 19.5" "Cell type enhanced" "Detected in some" "Corticotrophs: 75.2;Gonadotrophs: 46.6;Lactotrophs: 31.9;Other brain neurons: 16.8;Pancreatic islet cells: 55.9;Somatotrophs: 60.6;Thyrotrophs: 57.9" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 9.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 2.3;naive CD4 T-cell: 1.9" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "thyroid cancer: 2.6" "Liver - Hepatocytes, Pancreas - Alpha cells, Pancreas - Beta cells, Prostate - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA007034, HPA007093" Approved Supported Cytosol NA NA "Cluster 70: Non-specific - Protein processing" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 3 Cytosol "HPA007034: , HPA007093: " "unprognostic (1.56e-1)" "unprognostic (2.91e-3)" "unprognostic (6.59e-2)" "unprognostic (5.38e-3)" "unprognostic (9.02e-3)" "potential prognostic favorable (1.34e-4)" "unprognostic (4.41e-2)" "unprognostic (2.37e-1)" "unprognostic (5.54e-3)" "unprognostic (2.53e-1)" "unprognostic (6.93e-3)" GCKR ENSG00000084734 "Glucokinase regulator" 2 27496839-27523684 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "liver: 133.0" "Cell type enriched" "Detected in some" 4 "Hepatocytes: 166.3" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in many" 7 "Liver Hepatocellular Carcinoma (TCGA): 24.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 5.1" "Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB034098, HPA045855, HPA052227" Enhanced Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 7: Liver cancer - Metabolism" "Cluster 93: Hepatocytes - Bile production & excretion" 2 Nucleoplasm "Nucleoli, Cytosol" "CAB034098: , HPA045855: , HPA052227: " "unprognostic (3.20e-1)" "unprognostic (1.61e-1)" "unprognostic (2.01e-2)" "unprognostic (3.18e-1)" "unprognostic (6.71e-3)" "unprognostic (4.70e-1)" "potential prognostic favorable (1.34e-4)" "unprognostic (6.66e-3)" "unprognostic (2.53e-1)" "unprognostic (8.90e-3)" "unprognostic (2.09e-1)" "unprognostic (3.90e-1)" GCLC "GCS, GLCL, GLCLC" ENSG00000001084 "Glutamate-cysteine ligase catalytic subunit" P48506 6 53497341-53616970 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glutathione biosynthesis" Ligase "Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 142.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 298.6;Neuroendocrine cells: 358.7;Prostatic hillock cells: 342.1;Respiratory ciliated cells: 305.6;Urothelial cells: 1133.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Lung Squamous Cell Carcinoma (TCGA): 163.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 4.2" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 429.9" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Prostate - Prostate basal glandular cells, Spleen - Macrophages, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009569, HPA036359, HPA036360" Approved Approved Nucleoplasm,Nucleoli,Cytosol NA NA 6400000 "Cluster 41: Basophils - Unknown function" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 69: Urothelial cells - Basic cellular functions" 7 Nucleoplasm "Nucleoli, Cytosol" "CAB009569: , HPA036359: , HPA036360: " "unprognostic (5.35e-2)" "unprognostic (2.25e-2)" "unprognostic (1.62e-1)" "unprognostic (1.52e-2)" "unprognostic (1.58e-1)" "unprognostic (1.11e-1)" "unprognostic (1.32e-1)" "unprognostic (1.15e-1)" "unprognostic (2.03e-1)" "unprognostic (6.10e-3)" "potential prognostic favorable (1.50e-7)" "unprognostic (1.19e-3)" "potential prognostic unfavorable (6.65e-4)" "unprognostic (3.77e-1)" "unprognostic (7.49e-2)" "potential prognostic unfavorable (8.89e-4)" "unprognostic (7.22e-2)" "unprognostic (2.99e-1)" "unprognostic (6.42e-2)" "unprognostic (2.27e-1)" "unprognostic (1.72e-1)" "unprognostic (1.85e-1)" "unprognostic (1.49e-1)" "unprognostic (2.35e-2)" "potential prognostic favorable (9.49e-4)" "unprognostic (3.34e-1)" "unprognostic (2.33e-3)" "unprognostic (3.17e-1)" "unprognostic (2.07e-1)" "unprognostic (3.39e-2)" "unprognostic (1.37e-1)" GCLM GLCLR ENSG00000023909 "Glutamate-cysteine ligase modifier subunit" P48507 1 93885199-93909456 "Cancer-related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Glutathione biosynthesis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 45.3" "Cell type enhanced" "Detected in many" "Epididymal basal cells: 260.4;Epididymal clear cells: 308.2;Epididymal efferent duct ciliated cells: 453.7;Erythrocyte progenitors: 274.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in all" 9 "Gallbladder cancer: 586.6" "Adipose subcutaneous - Adipocytes (Subcutaneous), Skin - Outer root sheath cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009568, HPA023696, CAB040554" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 1500000 "Cluster 1: T-cells - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 8 "Nucleoplasm, Cytosol" "Plasma membrane" "CAB009568: , CAB040554: , HPA023696: " "unprognostic (2.10e-2)" "unprognostic (2.95e-1)" "unprognostic (1.50e-1)" "unprognostic (8.65e-2)" "potential prognostic favorable (6.29e-4)" "unprognostic (1.27e-1)" "unprognostic (5.64e-3)" "potential prognostic unfavorable (2.16e-4)" "unprognostic (7.72e-2)" "unprognostic (2.73e-2)" "potential prognostic favorable (1.34e-4)" "unprognostic (2.00e-2)" "potential prognostic unfavorable (7.37e-4)" "potential prognostic unfavorable (1.14e-5)" "unprognostic (6.77e-2)" "unprognostic (9.85e-3)" "unprognostic (1.42e-1)" "unprognostic (5.56e-2)" "unprognostic (3.70e-1)" "unprognostic (3.50e-1)" "unprognostic (1.33e-1)" "unprognostic (1.08e-1)" "unprognostic (1.40e-1)" "unprognostic (1.05e-1)" "unprognostic (8.69e-2)" "unprognostic (2.30e-1)" "unprognostic (3.16e-1)" "unprognostic (1.77e-1)" "unprognostic (2.31e-1)" "unprognostic (4.60e-2)" "unprognostic (5.64e-2)" GCM1 "GCMA, hGCMa" ENSG00000137270 "Glial cells missing transcription factor 1" Q9NP62 6 53126961-53148841 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "placenta: 19.0" "Group enriched" "Detected in some" 4 "Extravillous trophoblasts: 713.6;Syncytiotrophoblasts: 446.9" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.2" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in single" 13 "testis cancer: 7.6" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA011343, HPA073469" Enhanced NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 48: Non-specific - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 9 "HPA011343: , HPA073469: " "unprognostic (1.89e-1)" "unprognostic (3.14e-1)" "unprognostic (3.81e-2)" GCM2 "GCMB, hGCMb" ENSG00000124827 "Glial cells missing transcription factor 2" O75603 6 10873223-10882041 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 498 "parathyroid gland: 247.4" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 2.1;Epicardial cells: 4.5;Fibro-adipogenic progenitors: 1.3;Late primary spermatocytes: 2.7;Retinal amacrine cells: 3.2" "Low cell type specificity" "Detected in some" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 69: Parathyroid gland - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 30 GCN1 "GCN1L, GCN1L1, KIAA0219" ENSG00000089154 "GCN1 activator of EIF2AK4" Q92616 12 120127202-120194715 "Plasma proteins, Predicted intracellular proteins" "Stress response, Translation regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018799, HPA019648, HPA024367" Enhanced Enhanced Cytosol NA NA 180000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 38: Non-specific - Transcription" "Cluster 69: Urothelial cells - Basic cellular functions" 42 Cytosol "HPA018799: , HPA019648: , HPA024367: " "unprognostic (1.96e-1)" "unprognostic (8.71e-2)" "unprognostic (4.40e-2)" "unprognostic (9.49e-2)" "unprognostic (1.81e-1)" "unprognostic (2.12e-1)" "unprognostic (1.89e-2)" "unprognostic (3.19e-2)" "potential prognostic unfavorable (8.80e-4)" "potential prognostic favorable (3.88e-4)" "unprognostic (3.62e-1)" "unprognostic (3.75e-1)" "potential prognostic unfavorable (3.71e-6)" "unprognostic (4.22e-2)" "potential prognostic unfavorable (4.54e-5)" "unprognostic (1.95e-1)" "unprognostic (8.86e-3)" "unprognostic (1.53e-2)" "unprognostic (5.03e-2)" "unprognostic (2.11e-1)" "unprognostic (1.37e-1)" "unprognostic (1.57e-1)" "unprognostic (6.50e-2)" "unprognostic (1.05e-2)" "unprognostic (1.58e-1)" "unprognostic (1.02e-1)" "unprognostic (2.04e-1)" "unprognostic (1.09e-2)" "unprognostic (1.05e-1)" GCNA "ACRC, NAAR1" ENSG00000147174 "Germ cell nuclear acidic peptidase" Q96QF7 X 71578437-71613583 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 10.3" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 42.0;Differentiating spermatogonia: 84.6;Myonuclei: 50.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "HPA023476, HPA030870" Enhanced Supported Nucleoplasm NA NA "Cluster 67: Testis - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 20: Non-specific - Transcription regulation" Nucleoplasm "HPA023476: , HPA030870: " "unprognostic (1.29e-1)" "unprognostic (2.26e-2)" "potential prognostic favorable (2.40e-4)" "unprognostic (8.93e-3)" "unprognostic (2.15e-3)" "potential prognostic unfavorable (8.64e-4)" "unprognostic (9.04e-2)" "unprognostic (6.87e-2)" "unprognostic (1.42e-1)" GCNT1 "C2GNT, NACGT2, NAGCT2" ENSG00000187210 "Glucosaminyl (N-acetyl) transferase 1" Q02742 9 76419850-76651203 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 47.0;parathyroid gland: 79.0;stomach 1: 36.8;thyroid gland: 20.2" "Cell type enhanced" "Detected in many" "Colonocytes: 283.3;Corticotrophs: 235.1;Foveolar cells: 477.5;Mesothelial cells: 218.5;Mucous neck cells: 225.7;Neutrophil progenitors: 302.9;Tuft cells: 253.6" "Cell type enhanced" "Detected in all" "endothelial cell: 169.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 21.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Adrenal gland - Macrophages, Spleen - Macrophages, Stomach - Gastric mucous cells" "Group enriched" "Detected in all" 6 "cerebellum: 7.6;olfactory bulb: 24.9" "Low region specificity" "Detected in all" "HPA003522, HPA003523, HPA031151" Uncertain Supported "Nuclear speckles" NA NA 92000 "Cluster 29: Non-specific - Unknown function" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 72: Neuronal - Signal transduction" "Cluster 65: Non-specific - Cell growth & division" 5 "Nuclear speckles" "HPA003522: , HPA003523: , HPA031151: " "unprognostic (3.36e-2)" "unprognostic (2.57e-1)" "unprognostic (2.81e-2)" "unprognostic (2.47e-3)" "unprognostic (7.54e-2)" "unprognostic (1.17e-1)" "unprognostic (3.62e-2)" "unprognostic (2.98e-1)" "unprognostic (1.27e-1)" "unprognostic (1.01e-1)" "unprognostic (4.54e-3)" "unprognostic (2.66e-2)" "unprognostic (3.03e-3)" "unprognostic (7.48e-2)" "unprognostic (3.97e-1)" "unprognostic (9.68e-3)" "unprognostic (1.92e-1)" "unprognostic (1.15e-1)" "unprognostic (5.14e-2)" "unprognostic (8.91e-2)" "unprognostic (1.78e-1)" "unprognostic (2.76e-2)" "unprognostic (2.52e-1)" "unprognostic (2.16e-2)" "unprognostic (1.50e-3)" "unprognostic (3.03e-1)" "unprognostic (1.99e-1)" "unprognostic (1.69e-1)" "unprognostic (1.22e-1)" "unprognostic (1.34e-1)" GCNT2 "bA360O19.2, bA421M1.1, CCAT, GCNT5, IGNT, II, NACGT1, NAGCT1, ULG3" ENSG00000111846 "Glucosaminyl (N-acetyl) transferase 2 (I blood group)" Q8N0V5 6 10492223-10629368 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 13.7" "Group enriched" "Detected in many" 6 "Choroid plexus epithelial cells: 398.4;Distal convoluted tubule cells: 445.5;Loop of henle epithelial cells: 265.8;Microglia: 243.6;Oocytes: 548.0;Proximal tubule cells: 163.1;Renal collecting duct intercalated cells: 196.6;Renal connecting tubule cells: 145.2" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 285.1;choroid plexus epithelial cell: 310.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "basophil: 1.9" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 17.5;testis cancer: 19.4" "Adrenal gland - Endothelial cells, Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Testis - Spermatogonia" "Region enriched" "Detected in all" 4 "basal ganglia: 61.2" "Low region specificity" "Detected in many" HPA026776 Approved Approved "Golgi apparatus" No No 570000 "Cluster 29: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 1 "Golgi apparatus" "HPA026776: " "unprognostic (1.87e-1)" "unprognostic (2.58e-1)" "unprognostic (1.67e-1)" "potential prognostic favorable (1.21e-4)" "unprognostic (1.22e-1)" "unprognostic (3.69e-1)" "unprognostic (1.26e-1)" "potential prognostic favorable (2.43e-6)" "unprognostic (1.80e-2)" "unprognostic (1.09e-1)" "unprognostic (1.57e-1)" "unprognostic (1.12e-1)" "unprognostic (2.41e-1)" "unprognostic (5.73e-2)" "unprognostic (2.29e-1)" "unprognostic (3.63e-2)" "unprognostic (5.79e-2)" "unprognostic (1.07e-1)" "potential prognostic unfavorable (2.85e-4)" "unprognostic (6.29e-2)" "unprognostic (2.48e-2)" "unprognostic (4.05e-2)" "unprognostic (1.80e-1)" "unprognostic (1.32e-1)" "unprognostic (1.03e-1)" "unprognostic (3.55e-1)" GCNT3 "C2/4GnT, C2GnT-M, C2GnT2" ENSG00000140297 "Glucosaminyl (N-acetyl) transferase 3, mucin type" O95395 15 59594875-59640239 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 71.0;intestine: 133.9;salivary gland: 54.3" "Cell type enhanced" "Detected in many" "Colonocytes: 268.9;Conjunctival goblet cells: 133.0;Endometrial glandular cells: 163.2;Endometrial luminal cells: 83.6;Enteric transient amplifying cells: 68.5;Enterocytes: 179.7;Esophageal apical cells: 146.9;Foveolar cells: 82.9;Gastric progenitor cells: 85.9;Oocytes: 87.5;Papillary tip epithelial cells: 74.2;Renal collecting duct principal cells: 127.4;Salivary acinar cells: 86.8;Salivary duct cells: 113.0" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in many" "Pancreatic Adenocarcinoma (TCGA): 107.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 52.0;pancreatic cancer: 51.3" "Colon - Colon enterocytes, Kidney - Macrophages, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA011154 Enhanced Approved "Golgi apparatus,Vesicles" NA NA "Cluster 77: Intestine - Digestion" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 6 "Golgi apparatus" Vesicles "HPA011154: " "unprognostic (1.34e-1)" "unprognostic (1.68e-1)" "unprognostic (3.11e-2)" "unprognostic (9.87e-3)" "unprognostic (6.50e-2)" "unprognostic (1.96e-1)" "unprognostic (1.48e-2)" "unprognostic (1.00e-1)" "unprognostic (1.52e-1)" "unprognostic (1.09e-2)" "unprognostic (6.37e-3)" "validated prognostic unfavorable (3.52e-5)" "validated prognostic unfavorable (4.09e-4)" "unprognostic (3.42e-3)" "unprognostic (7.85e-2)" "unprognostic (1.46e-2)" "unprognostic (3.86e-1)" "unprognostic (1.96e-1)" "unprognostic (1.40e-1)" "unprognostic (1.92e-2)" "unprognostic (3.01e-1)" "unprognostic (2.22e-1)" "unprognostic (1.65e-2)" "unprognostic (1.36e-1)" "unprognostic (2.84e-2)" "unprognostic (5.27e-2)" "unprognostic (1.71e-2)" GCNT4 "C2GNT3, LINC01336" ENSG00000176928 "Glucosaminyl (N-acetyl) transferase 4" Q9P109 5 75025346-75052558 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 22.6;lymphoid tissue: 14.4;stomach 1: 17.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 71.1;Endometrial luminal cells: 44.2;Enterocytes: 40.3;Foveolar cells: 114.0;Mast cells: 48.8;Mucous neck cells: 65.6;Parietal cells: 77.8;Syncytiotrophoblasts: 44.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 22.5" "Group enriched" "Detected in many" 54 "granulocytes: 22.5;T-cells: 18.2" "Cancer enhanced" "Detected in many" "Rhabdoid: 8.7;testis cancer: 6.5" "Adipose subcutaneous - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA037431 Approved Supported "Nucleoplasm,Golgi apparatus" No NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 77: Intestine - Digestion" "Cluster 53: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 9: T-cells - Adaptive immunity: Regulation" "Golgi apparatus" Nucleoplasm "HPA037431: " "unprognostic (3.82e-1)" "unprognostic (1.07e-1)" "unprognostic (3.67e-1)" "potential prognostic favorable (3.55e-4)" "unprognostic (1.59e-1)" "unprognostic (1.60e-1)" "unprognostic (2.81e-2)" "unprognostic (1.20e-2)" "potential prognostic favorable (3.52e-7)" "unprognostic (4.17e-2)" "unprognostic (3.20e-2)" "unprognostic (4.14e-3)" "unprognostic (1.26e-1)" "unprognostic (7.09e-2)" "unprognostic (7.43e-2)" "unprognostic (4.55e-2)" "potential prognostic favorable (5.11e-4)" "unprognostic (1.19e-1)" "unprognostic (1.18e-1)" "unprognostic (8.13e-2)" "unprognostic (7.46e-2)" GCNT7 "C20orf105, dJ1153D9.2" ENSG00000124091 "Glucosaminyl (N-acetyl) transferase family member 7" Q6ZNI0 20 56491492-56525925 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 10 "bone marrow: 4.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 54.5;Early spermatids: 23.3;Epicardial cells: 111.4;Late spermatids: 25.2;Neutrophils: 28.9" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA052617, HPA059403" Uncertain Approved "Nuclear bodies,Vesicles,Cytosol" NA NA "Cluster 15: Bone marrow - Innate immune response" "Cluster 6: Non-specific - Immune response" "Cluster 56: Non-specific - Sensory perception" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "Nuclear bodies, Vesicles" Cytosol "HPA052617: , HPA059403: " "potential prognostic favorable (4.49e-4)" "potential prognostic favorable (8.30e-4)" GCOM1 "FLJ30973, GRINL1A, MYZAP-POLR2M" ENSG00000137878 "GCOM1, MYZAP-POLR2M combined locus" 15 57591908-57714745 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 18.8" "Cell type enhanced" "Detected in some" "Adipocytes: 16.4;Adrenal cortex cells: 12.9;Cardiomyocytes: 38.5;Lymphatic endothelial cells: 6.3;Papillary tip epithelial cells: 8.2;Platelets: 11.2;Smooth muscle cells: 8.7;Tuft cells: 11.5;Urothelial cells: 8.6" "Cell type enhanced" "Detected in some" "lower rhombic lip: 4.6;upper rhombic lip: 6.0" "Cancer enriched" "Detected in many" 5 "Kidney Chromophobe (TCGA): 19.1" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "naive B-cell: 1.4;naive CD4 T-cell: 1.4" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Pituitary gland - Gonadotropes, Prostate - Smooth muscle cells, Skin - Keratinocyte (granular), Stomach - Gastric mucous cells, Thyroid gland - Fibroblasts" "HPA039827, HPA068141" Approved Approved Nucleoplasm NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 58: Skin - Keratinization" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 6 Nucleoplasm "HPA039827: , HPA068141: " "unprognostic (1.63e-3)" "unprognostic (1.86e-2)" "unprognostic (6.69e-2)" "unprognostic (5.99e-2)" "unprognostic (9.42e-3)" "unprognostic (1.57e-1)" "unprognostic (2.16e-1)" "unprognostic (6.57e-2)" "unprognostic (4.77e-2)" "unprognostic (5.27e-3)" "unprognostic (2.27e-1)" "unprognostic (1.09e-1)" "unprognostic (8.80e-2)" "unprognostic (1.41e-3)" "unprognostic (1.29e-2)" "unprognostic (2.09e-1)" "unprognostic (1.36e-1)" "unprognostic (7.55e-2)" "unprognostic (2.37e-1)" "unprognostic (2.54e-1)" GCSAM "GCET2, HGAL, MGC40441" ENSG00000174500 "Germinal center associated signaling and motility" Q8N6F7 3 112120839-112133270 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "lymphoid tissue: 27.4;skin 1: 16.1" "Cell type enhanced" "Detected in some" "cDC: 2.1;Kupffer cells: 1.0;pDCs: 1.9;Renal collecting duct principal cells: 3.3;T-cells: 1.2" "Group enriched" "Detected in some" 4 "central nervous system macrophage: 1.1;leukocyte: 3.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in many" 5 "lymphoma: 53.4" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Urothelial cells, Skin - Keratinocyte (granular), Spleen - T-cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA002473 Approved NA NA "Cluster 24: Non-specific - Transcription" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 23: Choroid plexus - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 82: Dendritic cells - Antigen presentation" 4 "HPA002473: " "unprognostic (1.59e-2)" "unprognostic (7.44e-3)" "unprognostic (1.49e-2)" "unprognostic (1.86e-1)" "unprognostic (1.96e-2)" "unprognostic (4.30e-3)" "unprognostic (8.35e-3)" "unprognostic (4.18e-2)" "unprognostic (2.34e-1)" "unprognostic (2.19e-1)" "unprognostic (1.24e-1)" "unprognostic (2.37e-1)" "unprognostic (1.77e-1)" "unprognostic (8.06e-2)" "unprognostic (6.58e-3)" GCSAML "C1orf150, FLJ44728" ENSG00000169224 "Germinal center associated signaling and motility like" Q5JQS6 1 247507058-247577690 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.9;prostate: 5.1" "Cell type enhanced" "Detected in some" "Early primary spermatocytes: 23.8;Hematopoietic stem cells: 44.6;Late primary spermatocytes: 29.9;Mast cells: 228.9;Megakaryocyte progenitors: 66.0;Megakaryocytes: 117.5;Platelets: 82.9;Prostatic glandular cells: 57.1" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 4.9;upper rhombic lip: 13.2" "Cancer enriched" "Detected in single" 7 "Prostate Adenocarcinoma (TCGA): 3.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 670 "basophil: 228.8" "Lineage enriched" "Detected in single" 670 "granulocytes: 228.8" "Cancer enriched" "Detected in some" 13 "Leukemia: 24.5" "Adipose subcutaneous - Mast cells, Adipose visceral - Mast cells, Colon - Mast cells, Lung - Mast cells, Minor Salivary Gland - Mast cells, Prostate - Prostate glandular cells, Skin - Mast cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "HPA027507, HPA027510" Uncertain Approved Cytosol NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 64: Non-specific - Transcription" "Cluster 35: Non-specific - DNA binding" "Cluster 49: HMC-1 - Innate immune response" "Cluster 58: Mast cells - Allergic inflammatory responses" 7 Cytosol "HPA027507: , HPA027510: " "unprognostic (4.10e-3)" "unprognostic (1.35e-1)" "unprognostic (2.25e-2)" "unprognostic (3.17e-2)" "unprognostic (7.07e-3)" GCSH ENSG00000140905 "Glycine cleavage system protein H" P23434 16 81081945-81096395 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 134.4" "Cell type enhanced" "Detected in some" "Epididymal basal cells: 6.3;Epididymal clear cells: 4.1;Epididymal efferent duct absorptive cells: 11.6;Epididymal principal cells: 16.6;Extravillous trophoblasts: 5.9;Fallopian secretory cells: 5.2;Gastric chief cells: 8.7;Hepatocytes: 4.5;Paneth cells: 3.9;Parietal cells: 5.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041368, HPA057079" Supported Approved Vesicles NA NA 45000 "Cluster 30: Non-specific - DNA binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" 12 Vesicles "HPA041368: , HPA057079: " "unprognostic (9.13e-2)" "unprognostic (2.80e-2)" "unprognostic (4.08e-2)" "unprognostic (1.69e-2)" "unprognostic (2.92e-1)" "unprognostic (2.30e-1)" "unprognostic (1.67e-3)" "unprognostic (1.13e-2)" "unprognostic (7.00e-2)" "unprognostic (8.11e-2)" "unprognostic (4.95e-3)" "unprognostic (2.67e-1)" "unprognostic (4.47e-2)" "unprognostic (9.40e-2)" "unprognostic (5.55e-2)" "unprognostic (7.86e-2)" "unprognostic (7.20e-2)" "unprognostic (9.73e-2)" "unprognostic (8.08e-2)" "unprognostic (8.82e-3)" "unprognostic (1.35e-1)" "unprognostic (1.22e-2)" "potential prognostic unfavorable (2.76e-5)" "unprognostic (2.03e-2)" "unprognostic (5.96e-2)" "unprognostic (7.17e-2)" "unprognostic (1.06e-1)" "potential prognostic unfavorable (9.27e-4)" "unprognostic (7.12e-2)" "unprognostic (1.82e-1)" "unprognostic (1.02e-1)" GDA "CYPIN, GAH" ENSG00000119125 "Guanine deaminase" Q9Y2T3 9 72114595-72257193 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 69.9;intestine: 89.3;kidney: 40.1;liver: 57.4" "Group enriched" "Detected in many" 4 "Endometrial ciliated cells: 906.4;Endometrial glandular cells: 1151.2;Endometrial luminal cells: 2092.8;Endometrial secretory cells: 843.6;Enterocytes: 1690.7" "Cell type enhanced" "Detected in all" "deep-layer corticothalamic and 6b: 279.5;hippocampal CA1-3: 266.9" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 69.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal medulla cells, Colon - Colon enterocytes, Kidney - Proximal tubular cells, Stomach - Gastric mucous cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 7 "amygdala: 50.6;basal ganglia: 42.2;cerebral cortex: 84.8;hippocampal formation: 98.5;olfactory bulb: 26.5" "HPA019352, HPA024099, HPA030387" Enhanced Approved Nucleoplasm No NA 2100000 "Cluster 10: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 3 Nucleoplasm "HPA019352: , HPA024099: , HPA030387: " "unprognostic (7.44e-2)" "unprognostic (6.27e-2)" "unprognostic (6.71e-2)" "unprognostic (6.19e-2)" "unprognostic (1.70e-2)" "unprognostic (9.81e-2)" "unprognostic (2.64e-1)" "unprognostic (9.35e-3)" "potential prognostic favorable (5.57e-6)" "unprognostic (2.35e-2)" "unprognostic (1.16e-2)" "unprognostic (6.74e-2)" "unprognostic (1.37e-2)" "unprognostic (3.23e-2)" "unprognostic (5.19e-2)" "unprognostic (3.68e-2)" "unprognostic (2.30e-3)" "unprognostic (1.64e-1)" "unprognostic (1.02e-2)" "unprognostic (1.52e-1)" "unprognostic (4.24e-1)" "unprognostic (1.06e-1)" "unprognostic (2.04e-1)" "unprognostic (1.48e-1)" "unprognostic (8.51e-2)" "unprognostic (1.35e-1)" GDAP1 "CMT2K, CMT4, CMT4A" ENSG00000104381 "Ganglioside induced differentiation associated protein 1" Q8TB36 8 74320613-74518007 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 39.7" "Cell type enhanced" "Detected in many" "Bergmann glia: 306.0;Brain excitatory neurons: 448.0;Brain inhibitory neurons: 363.4;Cone photoreceptor cells: 304.3;Lactotrophs: 334.6;Oligodendrocyte progenitor cells: 470.9;Oligodendrocytes: 247.5;Other brain neurons: 362.6;Somatotrophs: 326.7;Thyrotrophs: 319.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014266, HPA024334" Enhanced Supported Mitochondria,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 73: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" 30 Mitochondria Cytosol "HPA014266: , HPA024334: " "unprognostic (2.66e-2)" "unprognostic (5.22e-2)" "unprognostic (2.10e-2)" "unprognostic (8.35e-2)" "unprognostic (2.53e-1)" "unprognostic (2.79e-1)" "unprognostic (2.08e-1)" "potential prognostic favorable (1.20e-4)" "unprognostic (1.60e-1)" "unprognostic (6.37e-2)" "potential prognostic favorable (7.86e-5)" "unprognostic (9.12e-2)" "unprognostic (7.11e-2)" "unprognostic (1.34e-2)" "unprognostic (2.13e-3)" "unprognostic (1.27e-1)" "unprognostic (2.33e-1)" "unprognostic (3.42e-3)" "unprognostic (4.52e-2)" "unprognostic (3.21e-1)" "unprognostic (3.46e-1)" "unprognostic (4.01e-3)" "unprognostic (3.39e-2)" "unprognostic (9.39e-2)" "unprognostic (8.38e-2)" "unprognostic (1.21e-1)" "unprognostic (2.23e-1)" "unprognostic (1.52e-1)" "unprognostic (1.32e-1)" "unprognostic (5.10e-2)" "unprognostic (1.15e-2)" GDAP1L1 ENSG00000124194 "Ganglioside induced differentiation associated protein 1 like 1" Q96MZ0 20 44247099-44280947 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 61.9;pituitary gland: 17.5" "Cell type enhanced" "Detected in many" "Adipocytes: 41.4;Brain excitatory neurons: 28.1;Brain inhibitory neurons: 28.2;Cardiomyocytes: 128.5;Late spermatids: 47.5;Other brain neurons: 28.4;Retinal amacrine cells: 38.2;Retinal bipolar cells: 25.4;Retinal ganglion cells: 50.2;Retinal horizontal cells: 22.0" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in some" 12 "Glioblastoma Multiforme (TCGA): 33.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 14 "Neuroblastoma: 111.7" "Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Pancreas - Alpha cells, Stomach - Gastric enteroendocrine cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054182, HPA063265" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" "Endoplasmic reticulum" "HPA054182: , HPA063265: " "unprognostic (3.63e-2)" "unprognostic (3.02e-1)" "unprognostic (2.56e-3)" "unprognostic (3.98e-2)" "unprognostic (1.45e-3)" "unprognostic (3.03e-3)" "unprognostic (3.34e-2)" "unprognostic (2.06e-1)" GDAP2 "dJ776P7.1, FLJ20142, MACROD3" ENSG00000196505 "Ganglioside induced differentiation associated protein 2" Q9NXN4 1 117863485-117929621 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 137.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046185 Approved Approved "Endoplasmic reticulum" Yes No "Cluster 42: Non-specific - Vesicular transport" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 8 "Endoplasmic reticulum" "HPA046185: " "unprognostic (2.86e-2)" "unprognostic (7.25e-2)" "unprognostic (2.34e-1)" "unprognostic (2.42e-1)" "unprognostic (2.58e-2)" "unprognostic (2.60e-2)" "unprognostic (3.55e-1)" "unprognostic (1.45e-2)" "unprognostic (1.85e-1)" "potential prognostic unfavorable (1.69e-5)" "potential prognostic favorable (7.65e-5)" "unprognostic (3.68e-2)" "unprognostic (1.19e-1)" "unprognostic (1.70e-3)" "unprognostic (1.26e-2)" "unprognostic (8.04e-2)" "unprognostic (5.03e-2)" "unprognostic (2.24e-2)" "unprognostic (3.83e-1)" "unprognostic (2.55e-2)" "unprognostic (7.82e-2)" "unprognostic (1.44e-3)" "unprognostic (2.79e-2)" "unprognostic (6.35e-3)" "unprognostic (1.03e-2)" "unprognostic (1.53e-1)" "unprognostic (1.19e-1)" "unprognostic (8.49e-2)" "unprognostic (5.29e-2)" "unprognostic (1.72e-2)" "unprognostic (8.66e-3)" GDE1 MIR16 ENSG00000006007 "Glycerophosphodiester phosphodiesterase 1" Q9NZC3 16 19501693-19522123 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Syncytiotrophoblasts: 443.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077420 Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 52: Non-specific - Cellular respiration" "Cluster 11: White matter - Signal transduction" "Cluster 54: Non-specific - Transcription" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 7 Vesicles "Nucleoplasm, Plasma membrane" "HPA077420: " "unprognostic (1.08e-1)" "unprognostic (2.43e-2)" "unprognostic (1.57e-1)" "unprognostic (2.83e-2)" "unprognostic (2.63e-2)" "unprognostic (1.66e-3)" "unprognostic (6.11e-2)" "unprognostic (1.82e-2)" "unprognostic (1.11e-2)" "unprognostic (1.48e-1)" "unprognostic (1.19e-1)" "unprognostic (5.61e-3)" "unprognostic (1.37e-1)" "potential prognostic unfavorable (2.87e-5)" "unprognostic (3.71e-2)" "unprognostic (2.74e-2)" "unprognostic (2.77e-1)" "unprognostic (9.16e-2)" "unprognostic (4.33e-1)" "unprognostic (1.90e-1)" "unprognostic (2.80e-3)" "unprognostic (6.86e-3)" "unprognostic (1.35e-1)" "unprognostic (1.43e-1)" "unprognostic (1.21e-1)" "unprognostic (1.38e-2)" "unprognostic (2.21e-2)" "unprognostic (1.47e-2)" "unprognostic (2.11e-1)" "unprognostic (1.13e-1)" "unprognostic (5.22e-3)" GDF1 ENSG00000130283 "Growth differentiation factor 1" P27539 19 18868545-18896158 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Cytokine, Growth factor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "brain: 41.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Secreted to blood" Cytokine NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 1: Neuronal - Visual perception" 1 "unprognostic (4.38e-2)" GDF10 BMP-3b ENSG00000266524 "Growth differentiation factor 10" P55107 10 47300197-47313577 "Plasma proteins, Predicted secreted proteins" Osteogenesis "Cytokine, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 17.3;retina: 17.0" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 53.2;Bergmann glia: 44.7;Fibroblasts: 21.8;Retinal amacrine cells: 7.6;Retinal bipolar cells: 14.0;Rod photoreceptor cells: 22.1;Schwann cells: 20.3" "Cell type enhanced" "Detected in many" "Bergmann glia: 44.6;midbrain-derived inhibitory: 15.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 24 "Bone cancer: 13.5" "Breast - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Testis - Sertoli cells, Thyroid gland - Fibroblasts" "Region enriched" "Detected in all" 8 "cerebellum: 42.5" "Low region specificity" "Detected in all" HPA015498 Uncertain Approved Vesicles "Secreted in other tissues" Cytokine NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 108: Fibroblasts - ECM organization" Vesicles "HPA015498: " "unprognostic (3.16e-2)" "unprognostic (1.18e-1)" "potential prognostic favorable (2.93e-5)" "unprognostic (1.71e-2)" "unprognostic (8.76e-2)" "unprognostic (3.68e-1)" "unprognostic (2.42e-1)" "unprognostic (1.57e-3)" GDF11 "BMP-11, BMP11" ENSG00000135414 "Growth differentiation factor 11" O95390 12 55743122-55757264 "Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cytokine, Growth factor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 20.0" "Cell type enriched" "Detected in many" 6 "Retinal pigment epithelial cells: 413.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Liver - Hepatic stellate cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069609, HPA072665" Approved Approved "Golgi apparatus,Vesicles" "Secreted to blood" Cytokine NA No 46400 330000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 46: Brainstem - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" 2 Vesicles "Golgi apparatus" "HPA069609: , HPA072665: " "unprognostic (2.19e-1)" "unprognostic (2.94e-2)" "unprognostic (4.56e-3)" "unprognostic (3.76e-2)" "unprognostic (5.32e-2)" "unprognostic (9.55e-2)" "unprognostic (5.57e-2)" "unprognostic (1.16e-1)" "unprognostic (9.23e-2)" "unprognostic (1.36e-1)" "unprognostic (3.01e-3)" "unprognostic (3.44e-3)" "unprognostic (3.13e-1)" "unprognostic (8.95e-2)" "unprognostic (9.82e-2)" "unprognostic (1.13e-1)" "unprognostic (3.85e-2)" "unprognostic (1.26e-1)" "unprognostic (5.84e-2)" "unprognostic (1.84e-1)" "unprognostic (1.34e-1)" "potential prognostic favorable (3.31e-4)" "unprognostic (1.46e-1)" "unprognostic (2.17e-1)" "unprognostic (6.44e-2)" "unprognostic (1.31e-1)" "unprognostic (6.18e-3)" "unprognostic (1.29e-1)" "unprognostic (3.71e-1)" "potential prognostic unfavorable (2.07e-4)" "unprognostic (1.55e-1)" GDF15 "MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB" ENSG00000130513 "Growth differentiation factor 15" Q99988 19 18374731-18389176 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins" "Cytokine, Hormone" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 328.4" "Cell type enhanced" "Detected in many" "Enteric stem cells: 610.3;Epididymal basal cells: 717.7;Pancreatic acinar cells: 2930.9;Pancreatic duct cells: 766.1;Prostatic club cells: 1044.5;Prostatic hillock cells: 1217.5;Syncytiotrophoblasts: 6139.3;Urothelial cells: 2097.1" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 9.7" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 9 "choroid plexus: 72.0" "Immune cell enhanced" "Detected in some" "neutrophil: 2.5" "Group enriched" "Detected in many" 4 "granulocytes: 2.5;monocytes: 1.1" "Cancer enhanced" "Detected in many" "prostate cancer: 802.0;skin cancer: 1117.4" "Minor Salivary Gland - Minor salivary glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA011191, CAB062554, HPA070957" Enhanced Enhanced "Golgi apparatus" "Secreted to blood" Cytokine NA NA 1260000 360000 "Cluster 21: Neutrophils - Unknown function" "Cluster 72: Kidney - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." 30 "Golgi apparatus" "CAB062554: , HPA011191: , HPA070957: " "unprognostic (5.42e-2)" "unprognostic (8.74e-2)" "unprognostic (2.03e-1)" "unprognostic (7.68e-2)" "unprognostic (5.43e-3)" "unprognostic (1.68e-2)" "unprognostic (1.41e-2)" "potential prognostic unfavorable (2.35e-4)" "unprognostic (1.65e-2)" "unprognostic (4.66e-3)" "unprognostic (2.01e-2)" "unprognostic (8.23e-2)" "unprognostic (1.89e-2)" "unprognostic (3.38e-3)" "unprognostic (1.75e-2)" "unprognostic (1.14e-2)" "unprognostic (1.56e-1)" "unprognostic (3.51e-1)" "unprognostic (3.40e-3)" "unprognostic (2.60e-1)" "unprognostic (1.73e-1)" "unprognostic (8.23e-2)" "unprognostic (6.59e-2)" "unprognostic (1.82e-1)" "unprognostic (1.04e-1)" "potential prognostic favorable (4.14e-4)" "unprognostic (6.99e-2)" "unprognostic (1.52e-2)" "unprognostic (1.15e-1)" "unprognostic (2.92e-1)" "unprognostic (1.98e-1)" GDF2 "BMP-9, BMP9" ENSG00000263761 "Growth differentiation factor 2" Q9UK05 10 47322454-47327588 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" Angiogenesis "Cytokine, Growth factor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 118 "liver: 17.4" "Cell type enriched" "Detected in some" 9 "Hepatic stellate cells: 19.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatic stellate cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB023357 Uncertain "Secreted to blood" Cytokine NA NA 2210000 860000 "Cluster 53: Liver - Plasma proteins" "Cluster 51: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 3 "CAB023357: " GDF3 ENSG00000184344 "Growth differentiation factor 3" Q9NR23 12 7689784-7695775 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Cytokine, Developmental protein, Growth factor" "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 5 "kidney: 4.3" "Group enriched" "Detected in some" 4 "Granulosa cells: 4.9;Lymphatic endothelial cells: 11.7" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 783 "Testicular Germ Cell Tumor (TCGA): 611.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 111 "testis cancer: 71.1" "Adipose subcutaneous - Smooth muscle cells, Kidney - Endothelial cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA018468 Uncertain "Secreted to blood" Cytokine NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 34: Testis cancer - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 1 "HPA018468: " "unprognostic (1.68e-1)" GDF5 "BMP14, CDMP1" ENSG00000125965 "Growth differentiation factor 5" P43026 20 35433347-35454746 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" Chondrogenesis "Cytokine, Growth factor" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "salivary gland: 9.3" "Cell type enhanced" "Detected in some" "Breast lactating cells: 3.0;Pituicytes/FSCs: 10.2;Salivary acinar cells: 11.3;Submucosal glandular cells: 3.4" "Cell type enriched" "Detected in some" 9 "fibroblast: 15.7" "Cancer enriched" "Detected in some" 4 "Uterine Corpus Endometrial Carcinoma (TCGA): 6.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 12.4" "Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Prostate - Smooth muscle cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA015648 Uncertain "Secreted to blood" Cytokine NA NA "Cluster 82: Salivary gland - Secretion" "Cluster 72: Neuronal - Signal transduction" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 2 "HPA015648: " "unprognostic (1.31e-2)" "unprognostic (7.91e-2)" "unprognostic (5.87e-2)" "unprognostic (9.81e-2)" "unprognostic (8.66e-3)" "unprognostic (1.74e-1)" "unprognostic (9.78e-2)" GDF6 "BMP13, KFS, KFS1, SGM1" ENSG00000156466 "Growth differentiation factor 6" Q6KF10 8 96142333-96160806 "Disease related genes, Human disease related genes, Predicted secreted proteins" Apoptosis "Cytokine, Developmental protein, Growth factor" "Deafness, Disease variant, Dwarfism, Leber congenital amaurosis, Microphthalmia, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 10.2" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 2.7;Early primary spermatocytes: 2.0;Epididymal basal cells: 7.6;Fibro-adipogenic progenitors: 5.2;Fibroblasts: 3.6;Granulosa cells: 1.6;Mesothelial cells: 4.6;Oligodendrocyte progenitor cells: 11.3;Oocytes: 4.6;Pancreatic acinar cells: 2.1" "Group enriched" "Detected in some" 4 "deep-layer near-projecting: 6.6;oligodendrocyte precursor cell: 11.5;thalamic excitatory: 3.7" "Cancer enhanced" "Detected in some" "Kidney Renal Clear Cell Carcinoma (TCGA): 6.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bone cancer: 31.8;Neuroblastoma: 10.7;Sarcoma: 11.2;testis cancer: 14.6" "Breast - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblasts_2, Spleen - Smooth muscle cells, Thyroid gland - Fibroblasts" "Not detected" "Not detected" "Region enriched" "Detected in single" 7 "midbrain: 2.0" HPA045206 Uncertain Supported "Nucleoplasm,Nuclear membrane,Vesicles" "Secreted to blood" Cytokine NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 1: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 108: Fibroblasts - ECM organization" Vesicles "Nucleoplasm, Nuclear membrane" "HPA045206: " "unprognostic (3.92e-1)" "unprognostic (9.23e-2)" "potential prognostic favorable (1.30e-6)" "unprognostic (6.94e-3)" "unprognostic (1.20e-1)" "unprognostic (3.84e-1)" "unprognostic (5.03e-2)" "unprognostic (1.87e-2)" GDF7 BMP12 ENSG00000143869 "Growth differentiation factor 7" Q7Z4P5 2 20667144-20679243 "Predicted secreted proteins" "Cytokine, Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 12.2;cervix: 9.7;seminal vesicle: 21.1" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 31.9;B-cells: 10.9;Decidual stromal cells: 33.7;Endometrial stromal cells: 120.3;Loop of henle epithelial cells: 10.8;Papillary tip epithelial cells: 11.3;Prostatic club cells: 28.4;Proximal tubule cells: 20.8" "Cell type enhanced" "Detected in many" "thalamic excitatory: 7.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "liver cancer: 1.4" "Adipose subcutaneous - Smooth muscle cells, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Not detected" "Not detected" HPA069106 Approved Vesicles "Secreted in other tissues" Cytokine NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 55: Lymphoma - Immune response" "Cluster 108: Fibroblasts - ECM organization" Vesicles "HPA069106: " "unprognostic (1.79e-3)" "unprognostic (7.13e-3)" "validated prognostic favorable (3.55e-5)" "validated prognostic favorable (1.14e-4)" "unprognostic (1.18e-1)" "unprognostic (1.96e-2)" "unprognostic (1.93e-1)" GDF9 ENSG00000164404 "Growth differentiation factor 9" O60383 5 132861181-132866884 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cytokine, Growth factor" "Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 3.4;testis: 6.6" "Group enriched" "Detected in many" 4 "Cardiomyocytes: 81.6;Oocytes: 184.2" "Low cell type specificity" "Detected in some" "Cancer enriched" "Detected in some" 6 "Breast Invasive Carcinoma (TCGA): 7.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA069146 Supported Approved "Golgi apparatus,Cytosol" "Secreted in female reproductive system" Cytokine NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 41: Oocytes - Oogenesis" 9 "Golgi apparatus" Cytosol "HPA069146: " "unprognostic (3.13e-1)" "unprognostic (2.51e-2)" "unprognostic (4.44e-2)" "potential prognostic favorable (5.20e-4)" GDI1 "FLJ41411, GDIL, MRX41, MRX48, OPHN2, RABGDIA, XAP-4" ENSG00000203879 "GDP dissociation inhibitor 1" P31150 X 154436913-154443467 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 501.7" "Cell type enhanced" "Detected in many" "Oocytes: 147.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012979, HPA049290, HPA057668" Enhanced Supported "Plasma membrane,Cytosol" NA NA 32000000 "Cluster 45: Eosinophils - Unknown function" "Cluster 27: Cerebellum - Synaptic function" "Cluster 14: Neurons - Synaptic function" "Cluster 36: Non-specific - mRNA processing" "Cluster 80: Oligodendrocytes - Myelination" 112 Cytosol "Plasma membrane" "CAB012979: , HPA049290: , HPA057668: " "unprognostic (9.34e-2)" "potential prognostic unfavorable (6.13e-6)" "unprognostic (1.33e-1)" "unprognostic (5.65e-1)" "unprognostic (1.00e-2)" "potential prognostic unfavorable (1.72e-4)" "unprognostic (3.69e-1)" "unprognostic (6.63e-2)" "potential prognostic unfavorable (1.55e-4)" "unprognostic (3.18e-2)" "potential prognostic favorable (1.89e-4)" "unprognostic (3.23e-1)" "unprognostic (3.49e-1)" "unprognostic (2.24e-3)" "unprognostic (5.02e-2)" "unprognostic (2.49e-2)" "unprognostic (1.28e-2)" "unprognostic (7.06e-2)" "unprognostic (2.31e-1)" "unprognostic (4.92e-2)" "unprognostic (1.13e-3)" "unprognostic (1.07e-3)" "unprognostic (2.36e-2)" "unprognostic (6.46e-2)" "unprognostic (1.78e-1)" "unprognostic (3.73e-1)" "unprognostic (3.51e-2)" "unprognostic (3.80e-1)" "unprognostic (5.44e-2)" "unprognostic (1.57e-1)" "unprognostic (1.31e-1)" GDI2 RABGDIB ENSG00000057608 "GDP dissociation inhibitor 2" P50395 10 5765223-5842132 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 851.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049290, HPA057668" Supported Approved "Plasma membrane,Cytosol" NA NA 43000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 61: Non-specific - Transcription" "Cluster 30: White matter - Myelination" "Cluster 52: Non-specific - Mitochondria" "Cluster 82: Dendritic cells - Antigen presentation" 80 "Plasma membrane, Cytosol" "HPA049290: , HPA057668: " "unprognostic (2.17e-1)" "unprognostic (6.20e-3)" "unprognostic (4.24e-1)" "unprognostic (1.44e-2)" "unprognostic (3.72e-2)" "unprognostic (4.67e-2)" "unprognostic (1.28e-2)" "potential prognostic favorable (2.96e-5)" "unprognostic (1.84e-1)" "unprognostic (2.88e-2)" "potential prognostic favorable (1.19e-9)" "unprognostic (4.64e-2)" "unprognostic (1.79e-1)" "validated prognostic unfavorable (9.00e-8)" "validated prognostic unfavorable (6.67e-4)" "unprognostic (1.42e-1)" "unprognostic (1.02e-2)" "unprognostic (1.81e-1)" "unprognostic (3.43e-2)" "unprognostic (1.14e-1)" "unprognostic (2.85e-3)" "unprognostic (6.27e-3)" "unprognostic (1.23e-1)" "unprognostic (1.36e-1)" "unprognostic (6.21e-3)" "unprognostic (3.36e-3)" "unprognostic (1.52e-1)" "unprognostic (3.51e-1)" "unprognostic (4.59e-2)" "unprognostic (1.37e-2)" "unprognostic (2.84e-2)" GDNF "ATF1, ATF2, HFB1-GDNF" ENSG00000168621 "Glial cell derived neurotrophic factor" P39905 5 37812677-37840041 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Cancer-related genes, Disease variant, Hirschsprung disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 7.7;skeletal muscle: 9.7" "Cell type enhanced" "Detected in some" "Epididymal basal cells: 70.5;Medullary thymic epithelial cells: 12.0;Myonuclei: 9.3;Respiratory basal cells: 12.6;Schwann cells: 35.0;Thymic myoid cells: 43.5" "Cell type enhanced" "Detected in some" "eccentric medium spiny neuron: 5.5;thalamic excitatory: 7.3;upper rhombic lip: 6.5" "Cancer enhanced" "Detected in some" "Skin Cutaneous Melanoma (TCGA): 3.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 20.0" "Region enhanced" "Detected in single" "basal ganglia: 2.8" "Low region specificity" "Detected in some" "CAB005210, HPA070283" Supported Approved Nucleoplasm,Vesicles "Secreted in other tissues" "Growth factor" NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 3 Vesicles Nucleoplasm "CAB005210: , HPA070283: " "unprognostic (1.21e-1)" "potential prognostic favorable (5.65e-4)" "unprognostic (7.72e-2)" "unprognostic (1.62e-3)" "unprognostic (6.19e-2)" "unprognostic (8.67e-3)" "unprognostic (1.45e-1)" "unprognostic (3.25e-2)" "unprognostic (9.47e-2)" GDPD1 "FLJ37451, GDE4" ENSG00000153982 "Glycerophosphodiester phosphodiesterase domain containing 1" Q8N9F7 17 59220467-59275970 "Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.2" "Cell type enhanced" "Detected in many" "Astrocytes: 54.3;Brain excitatory neurons: 78.6;Brain inhibitory neurons: 74.7;Early primary spermatocytes: 112.4;Early spermatids: 82.9;Ependymal cells: 55.7;Megakaryocyte-Erythroid progenitors: 71.5;Oligodendrocyte progenitor cells: 58.6;Other brain neurons: 55.2;Retinal ganglion cells: 81.1;Tuft cells: 69.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 37: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 109: Neurons - Neuronal signaling" 3 "unprognostic (2.13e-2)" "unprognostic (2.87e-2)" "unprognostic (6.95e-2)" "unprognostic (6.25e-2)" "unprognostic (7.34e-3)" "unprognostic (4.22e-1)" "unprognostic (2.41e-1)" "unprognostic (1.72e-3)" "unprognostic (2.79e-1)" "unprognostic (2.51e-3)" "unprognostic (1.25e-1)" "unprognostic (1.10e-2)" "unprognostic (2.30e-1)" "validated prognostic unfavorable (2.58e-5)" "validated prognostic unfavorable (2.56e-8)" "unprognostic (1.20e-2)" "unprognostic (1.99e-1)" "unprognostic (1.56e-1)" "unprognostic (7.98e-2)" "unprognostic (9.71e-2)" "unprognostic (8.42e-2)" "unprognostic (8.79e-3)" "unprognostic (2.91e-1)" "unprognostic (1.57e-1)" "unprognostic (2.11e-2)" "unprognostic (8.59e-3)" "unprognostic (8.23e-2)" "unprognostic (1.27e-3)" "unprognostic (1.49e-1)" "unprognostic (5.26e-2)" "unprognostic (6.07e-2)" GDPD2 "FLJ20207, GDE3, OBDPF" ENSG00000130055 "Glycerophosphodiester phosphodiesterase domain containing 2" Q9HCC8 X 70423031-70433390 "Enzymes, Metabolic proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 19.6;lymphoid tissue: 58.9;skin 1: 45.1" "Cell type enhanced" "Detected in some" "Astrocytes: 17.4;Basal keratinocytes: 46.2;Cardiomyocytes: 11.6;Colonocytes: 24.4;Enterocytes: 88.8;Ependymal cells: 22.6;Migrating cytotrophoblasts: 17.0;Müller glia: 28.9;Ocular epithelial cells: 15.1;Pituitary stem cells: 14.9" "Cell type enhanced" "Detected in some" "astrocyte: 21.5;ependymal cell: 26.6" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 18.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 6.2" "Colon - Colon enterocytes, Skin - Keratinocyte (other), Spleen - Fibroblasts_1, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 66: Lymphoid tissue - Immune response" "Cluster 46: Brainstem - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" "unprognostic (2.48e-1)" "unprognostic (8.12e-2)" "unprognostic (1.92e-1)" "unprognostic (1.98e-2)" "unprognostic (1.53e-1)" "unprognostic (1.26e-2)" "potential prognostic unfavorable (3.11e-4)" "unprognostic (6.93e-2)" "unprognostic (1.98e-1)" "unprognostic (4.59e-2)" "unprognostic (2.25e-1)" "unprognostic (7.56e-2)" "unprognostic (4.05e-2)" "unprognostic (1.64e-2)" "unprognostic (1.20e-2)" "unprognostic (3.64e-3)" "unprognostic (6.30e-2)" "unprognostic (7.10e-2)" GDPD3 MGC4171 ENSG00000102886 "Glycerophosphodiester phosphodiesterase domain containing 3" Q7L5L3 16 30104810-30113537 "Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 66.4" "Group enriched" "Detected in many" 6 "Esophageal apical cells: 799.7;Late spermatids: 706.0" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Bladder Urothelial Carcinoma (TCGA): 63.3" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "neutrophil: 2.5" "Lineage enriched" "Detected in single" 23 "granulocytes: 2.5" "Cancer enhanced" "Detected in many" "breast cancer: 20.8" "Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA041148, HPA041470" Uncertain Approved "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes NA "Cluster 35: Neutrophils - Protein binding" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 84: Apical squamous epithelium - Cornification" Nucleoplasm "Cytokinetic bridge, Cytosol" "HPA041148: , HPA041470: " "unprognostic (8.18e-2)" "unprognostic (7.17e-2)" "unprognostic (3.61e-1)" "unprognostic (8.67e-2)" "unprognostic (2.03e-1)" "unprognostic (2.26e-1)" "unprognostic (1.75e-1)" "unprognostic (1.65e-2)" "unprognostic (1.11e-1)" "unprognostic (1.79e-1)" "unprognostic (1.52e-2)" "unprognostic (2.00e-1)" "unprognostic (1.27e-2)" "potential prognostic unfavorable (3.27e-4)" "unprognostic (3.21e-3)" "unprognostic (3.16e-2)" "unprognostic (1.62e-1)" "unprognostic (4.43e-2)" "unprognostic (2.58e-1)" "unprognostic (1.28e-2)" "unprognostic (3.37e-2)" "unprognostic (1.91e-2)" "unprognostic (4.05e-2)" "unprognostic (3.24e-1)" "unprognostic (4.75e-2)" "unprognostic (2.43e-1)" "unprognostic (7.29e-2)" "unprognostic (1.97e-1)" "unprognostic (4.87e-1)" "unprognostic (1.84e-1)" "unprognostic (1.06e-1)" GDPD4 GDE6 ENSG00000178795 "Glycerophosphodiester phosphodiesterase domain containing 4" Q6W3E5 11 77216558-77301687 "Predicted membrane proteins" Hydrolase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "retina: 1.4;testis: 3.6" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 16.7;Early primary spermatocytes: 127.1;Extravillous trophoblasts: 15.2;Hepatocytes: 11.3;Late primary spermatocytes: 19.8;Late spermatids: 21.9;Oocytes: 18.4;Rod photoreceptor cells: 13.1;Undifferentiated spermatogonia: 36.5" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 3.6" "Cancer enriched" "Detected in single" 13 "Testicular Germ Cell Tumor (TCGA): 2.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Bile duct cancer: 1.1" "Liver - Hepatocytes" "Region enriched" "Detected in single" 23 "olfactory bulb: 2.3" "Not detected" "Not detected" NA NA "Cluster 47: Testis - Mixed function" "Cluster 44: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 3: Early primary spermatocytes - Early meiosis" "potential prognostic favorable (2.43e-4)" "unprognostic (3.13e-1)" GDPD5 "GDE2, PP1665" ENSG00000158555 "Glycerophosphodiester phosphodiesterase domain containing 5" Q8WTR4 11 75434640-75525941 "Enzymes, Predicted membrane proteins" "Lipid metabolism, Neurogenesis" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 112.9;retina: 77.5" "Cell type enhanced" "Detected in many" "Adipocytes: 100.9;Cone photoreceptor cells: 231.9;Early spermatids: 68.8;Late spermatids: 309.2;Pituitary stem cells: 76.2;Retinal bipolar cells: 91.2;Rod photoreceptor cells: 160.1;Syncytiotrophoblasts: 134.6;Tuft cells: 103.8" "Cell type enhanced" "Detected in many" "fibroblast: 44.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 7.7" "Group enriched" "Detected in many" 6 "granulocytes: 7.7;T-cells: 2.0" "Low cancer specificity" "Detected in many" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065257, HPA066762, HPA069281" Uncertain Approved "Golgi apparatus" No No "Cluster 3: Non-specific - Nuclear processes" "Cluster 64: Non-specific - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 79: Photoreceptor cells - Phototransduction" 3 "Golgi apparatus" "HPA065257: , HPA066762: , HPA069281: " "unprognostic (1.07e-1)" "unprognostic (5.42e-2)" "potential prognostic favorable (1.14e-4)" "unprognostic (7.41e-2)" "unprognostic (2.02e-1)" "unprognostic (1.50e-2)" "unprognostic (2.15e-1)" "unprognostic (4.77e-3)" "unprognostic (9.94e-3)" "unprognostic (3.89e-2)" "unprognostic (1.79e-3)" "unprognostic (9.74e-2)" "unprognostic (1.65e-3)" "unprognostic (1.58e-3)" "unprognostic (6.23e-2)" "unprognostic (4.28e-2)" "unprognostic (1.69e-1)" "unprognostic (2.30e-2)" "unprognostic (2.41e-1)" "unprognostic (2.62e-1)" "unprognostic (3.57e-1)" "unprognostic (2.09e-2)" "unprognostic (2.84e-2)" "unprognostic (1.79e-1)" "unprognostic (7.46e-2)" "unprognostic (5.70e-3)" "unprognostic (1.63e-1)" "unprognostic (8.46e-2)" "unprognostic (6.71e-2)" "potential prognostic unfavorable (6.00e-4)" "unprognostic (7.30e-2)" GDPGP1 C15orf58 ENSG00000183208 "GDP-D-glucose phosphorylase 1" Q6ZNW5 15 90233808-90245811 "Enzymes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor, Hydrolase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 6.3" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 4.6;Mesothelial cells: 1.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048189, HPA059841" Approved Approved Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 48: Non-specific - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" Cytosol "HPA048189: , HPA059841: " "unprognostic (1.53e-1)" "unprognostic (9.55e-2)" "unprognostic (9.84e-2)" "unprognostic (3.88e-2)" "unprognostic (2.27e-2)" "unprognostic (2.86e-1)" "unprognostic (4.59e-3)" "unprognostic (4.99e-2)" "unprognostic (7.86e-3)" "unprognostic (2.93e-1)" "unprognostic (2.75e-1)" "unprognostic (5.93e-3)" "unprognostic (3.29e-1)" "unprognostic (7.83e-2)" "unprognostic (1.18e-3)" "unprognostic (1.87e-1)" "unprognostic (7.75e-3)" "unprognostic (8.09e-3)" "unprognostic (2.17e-1)" "unprognostic (1.50e-1)" "unprognostic (3.30e-1)" "unprognostic (5.27e-2)" "unprognostic (1.52e-1)" "unprognostic (3.87e-3)" "unprognostic (1.07e-1)" "unprognostic (4.57e-3)" "unprognostic (2.02e-1)" "unprognostic (3.60e-2)" "unprognostic (4.75e-2)" GEM KIR ENSG00000164949 "GTP binding protein overexpressed in skeletal muscle" P55040 8 94249253-94262350 "Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "gallbladder: 214.9" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 292.0;Endometrial stromal cells: 180.3;Fibroblasts: 402.1;Hepatic stellate cells: 232.4;Pericytes: 372.4;Retinal pigment epithelial cells: 400.7;Salivary myoepithelial cells: 264.6;Smooth muscle cells: 414.1;Vascular smooth muscle cells: 334.9" "Group enriched" "Detected in many" 13 "astrocyte: 63.4;choroid plexus epithelial cell: 106.5;ependymal cell: 51.0;pericyte: 45.8;vascular associated smooth muscle cell: 142.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "myeloid DC: 1.4" "Lineage enriched" "Detected in single" 5 "dendritic cells: 1.4" "Low cancer specificity" "Detected in many" "Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in many" "Region enhanced" "Detected in all" "spinal cord: 37.1" HPA024798 Approved NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 103: Non-specific - Basic cellular processes" 90 "HPA024798: " "unprognostic (5.62e-3)" "unprognostic (1.41e-1)" "unprognostic (6.85e-2)" "unprognostic (1.04e-1)" "unprognostic (1.63e-1)" "unprognostic (5.09e-2)" "unprognostic (3.41e-1)" "unprognostic (1.21e-1)" "unprognostic (3.60e-1)" "unprognostic (1.67e-1)" "unprognostic (1.81e-1)" "unprognostic (7.75e-2)" "unprognostic (3.88e-2)" "unprognostic (1.96e-1)" "unprognostic (3.97e-2)" "unprognostic (1.03e-1)" "unprognostic (3.93e-1)" "unprognostic (6.33e-2)" "unprognostic (1.53e-2)" "unprognostic (2.12e-2)" "unprognostic (1.22e-1)" "unprognostic (5.28e-2)" "unprognostic (2.31e-1)" "unprognostic (1.06e-1)" "unprognostic (1.57e-1)" "potential prognostic favorable (7.26e-4)" "unprognostic (3.87e-2)" "unprognostic (1.36e-2)" "unprognostic (8.47e-2)" "potential prognostic unfavorable (2.79e-4)" "unprognostic (4.63e-2)" GEMIN2 SIP1 ENSG00000092208 "Gem nuclear organelle associated protein 2" O14893 14 39114285-39136973 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 58.6;Late spermatids: 64.8;Oocytes: 73.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015426, HPA046570, HPA057114" Enhanced Supported "Nucleoplasm,Nucleoli,Nuclear bodies" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 48: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 45 "Nucleoplasm, Nuclear bodies" Nucleoli "CAB015426: , HPA046570: , HPA057114: " "unprognostic (1.14e-3)" "unprognostic (1.31e-1)" "unprognostic (8.29e-2)" "unprognostic (1.73e-2)" "unprognostic (1.26e-1)" "unprognostic (1.98e-1)" "unprognostic (4.53e-3)" "unprognostic (6.40e-3)" "unprognostic (9.88e-3)" "potential prognostic favorable (7.48e-4)" "unprognostic (1.04e-1)" "unprognostic (2.37e-1)" "potential prognostic unfavorable (2.11e-7)" "unprognostic (1.59e-1)" "unprognostic (5.06e-3)" "unprognostic (2.78e-2)" "unprognostic (9.07e-2)" "unprognostic (7.31e-3)" "unprognostic (1.18e-2)" "unprognostic (6.69e-2)" "unprognostic (1.49e-3)" "unprognostic (6.17e-2)" "unprognostic (1.52e-1)" "unprognostic (3.72e-3)" "unprognostic (7.84e-2)" "unprognostic (1.68e-1)" "unprognostic (1.35e-1)" "unprognostic (1.30e-1)" "unprognostic (5.69e-2)" GEMIN4 "DKFZP434B131, DKFZP434D174, HC56, HCAP1, HHRF-1, p97" ENSG00000179409 "Gem nuclear organelle associated protein 4" P57678 17 744421-753999 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 9 "Early spermatids: 155.1;Late primary spermatocytes: 135.6;Late spermatids: 246.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065699, HPA067891" Uncertain Supported "Nuclear bodies,Cytosol" NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 47: Testis - Mixed function" "Cluster 35: Non-specific - DNA binding" "Cluster 42: Non-specific - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 103 "Nuclear bodies, Cytosol" "HPA065699: , HPA067891: " "unprognostic (6.25e-2)" "unprognostic (1.36e-1)" "unprognostic (1.40e-2)" "unprognostic (2.84e-1)" "unprognostic (1.33e-2)" "unprognostic (1.59e-1)" "unprognostic (3.74e-1)" "unprognostic (1.44e-2)" "unprognostic (1.39e-1)" "unprognostic (4.21e-3)" "validated prognostic favorable (3.76e-5)" "validated prognostic favorable (6.15e-4)" "unprognostic (1.96e-1)" "unprognostic (2.63e-3)" "unprognostic (3.80e-1)" "unprognostic (4.30e-2)" "unprognostic (7.98e-2)" "unprognostic (1.74e-1)" "unprognostic (2.04e-2)" "unprognostic (1.51e-1)" "unprognostic (1.04e-2)" "unprognostic (6.00e-2)" "unprognostic (4.87e-2)" "unprognostic (1.06e-1)" "unprognostic (1.80e-3)" "unprognostic (1.67e-1)" "unprognostic (2.26e-1)" "unprognostic (3.35e-1)" "unprognostic (2.70e-2)" "unprognostic (1.75e-2)" "unprognostic (3.96e-3)" GEMIN5 ENSG00000082516 "Gem nuclear organelle associated protein 5" Q8TEQ6 5 154887411-154938211 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing, Protein biosynthesis, Translation regulation" RNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037392, HPA037393" Uncertain Enhanced "Nuclear bodies,Cytosol" NA NA 11000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 104: Brain endothelial cells - Blood brain barrier" 76 Cytosol "Nuclear bodies" "HPA037392: , HPA037393: " "unprognostic (1.54e-1)" "unprognostic (1.89e-2)" "unprognostic (2.84e-1)" "potential prognostic unfavorable (3.85e-5)" "unprognostic (4.79e-2)" "unprognostic (4.14e-2)" "unprognostic (2.14e-1)" "unprognostic (2.30e-1)" "unprognostic (4.22e-2)" "potential prognostic unfavorable (3.93e-5)" "potential prognostic favorable (1.25e-6)" "unprognostic (5.83e-2)" "unprognostic (2.20e-2)" "potential prognostic unfavorable (8.84e-4)" "unprognostic (5.59e-3)" "unprognostic (2.60e-1)" "potential prognostic unfavorable (1.10e-4)" "unprognostic (1.70e-1)" "unprognostic (1.05e-1)" "unprognostic (1.57e-1)" "unprognostic (3.51e-2)" "unprognostic (2.56e-1)" "unprognostic (1.01e-1)" "unprognostic (5.97e-2)" "unprognostic (2.42e-2)" "unprognostic (8.84e-3)" "unprognostic (5.29e-2)" "unprognostic (2.41e-2)" "unprognostic (6.15e-2)" "unprognostic (2.37e-2)" "unprognostic (1.53e-1)" GEMIN6 FLJ23459 ENSG00000152147 "Gem nuclear organelle associated protein 6" Q8WXD5 2 38751534-38785002 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 131.2;Late primary spermatocytes: 286.9;Late spermatids: 60.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035726, HPA035727" Approved Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 47: Testis - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" 53 "Nucleoplasm, Nuclear bodies" "HPA035726: , HPA035727: " "unprognostic (2.92e-3)" "unprognostic (8.69e-2)" "unprognostic (1.13e-1)" "unprognostic (2.02e-1)" "unprognostic (1.22e-1)" "potential prognostic favorable (1.44e-5)" "unprognostic (4.59e-3)" "unprognostic (1.57e-1)" "unprognostic (2.70e-3)" "unprognostic (2.68e-2)" "unprognostic (4.77e-2)" "unprognostic (4.82e-1)" "potential prognostic unfavorable (1.14e-4)" "validated prognostic unfavorable (4.22e-5)" "validated prognostic unfavorable (1.52e-6)" "unprognostic (1.41e-3)" "unprognostic (2.84e-3)" "unprognostic (2.00e-3)" "unprognostic (1.69e-1)" "unprognostic (1.14e-2)" "unprognostic (9.29e-3)" "unprognostic (1.16e-3)" "unprognostic (1.50e-1)" "unprognostic (1.33e-1)" "unprognostic (2.98e-2)" "unprognostic (7.56e-2)" "unprognostic (6.78e-3)" "unprognostic (1.10e-1)" "unprognostic (7.54e-2)" "unprognostic (5.85e-2)" "unprognostic (5.11e-1)" GEMIN7 FLJ13956 ENSG00000142252 "Gem nuclear organelle associated protein 7" Q9H840 19 45079195-45091518 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in single" "Myonuclei: 1.4" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052075 Supported Nucleoplasm,Cytosol NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 4: Non-specific - Transcription" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 31 "Nucleoplasm, Cytosol" "HPA052075: " "unprognostic (7.74e-2)" "unprognostic (4.22e-2)" "unprognostic (7.69e-2)" "unprognostic (2.95e-3)" "unprognostic (2.70e-3)" "unprognostic (6.41e-2)" "unprognostic (7.35e-2)" "unprognostic (2.34e-1)" "unprognostic (4.91e-3)" "unprognostic (1.17e-2)" "unprognostic (1.97e-2)" "unprognostic (9.91e-2)" "unprognostic (8.09e-2)" "potential prognostic unfavorable (2.39e-5)" "unprognostic (2.01e-2)" "unprognostic (3.29e-3)" "unprognostic (2.43e-1)" "unprognostic (7.76e-3)" "unprognostic (2.97e-2)" "unprognostic (9.58e-2)" "unprognostic (1.40e-1)" "unprognostic (1.98e-3)" "unprognostic (3.52e-1)" "unprognostic (9.98e-2)" "unprognostic (9.21e-2)" "unprognostic (4.40e-1)" "unprognostic (1.50e-1)" "unprognostic (2.15e-1)" "unprognostic (2.93e-1)" "unprognostic (1.80e-1)" "unprognostic (2.04e-1)" GEMIN8 "FAM51A1, FLJ20514" ENSG00000046647 "Gem nuclear organelle associated protein 8" Q9NWZ8 X 14006726-14029893 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028613 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 64: Non-specific - Transcription" "Cluster 30: White matter - Myelination" "Cluster 36: Non-specific - mRNA processing" "Cluster 7: Non-specific - Transcription" 44 "Nucleoplasm, Cytosol" "HPA028613: " "unprognostic (7.98e-2)" "unprognostic (2.47e-1)" "unprognostic (3.99e-1)" "unprognostic (8.38e-2)" "unprognostic (3.23e-2)" "unprognostic (3.15e-1)" "unprognostic (2.51e-1)" "unprognostic (2.69e-1)" "unprognostic (6.42e-2)" "unprognostic (2.49e-1)" "unprognostic (8.39e-3)" "unprognostic (1.42e-2)" "unprognostic (2.49e-1)" "potential prognostic unfavorable (1.90e-4)" "unprognostic (1.68e-1)" "unprognostic (5.31e-3)" "unprognostic (1.75e-1)" "unprognostic (3.47e-2)" "unprognostic (2.58e-2)" "unprognostic (1.65e-1)" "unprognostic (3.19e-1)" "unprognostic (7.28e-2)" "unprognostic (3.51e-2)" "unprognostic (1.51e-2)" "unprognostic (2.97e-1)" "unprognostic (9.94e-2)" "unprognostic (1.29e-1)" "unprognostic (5.25e-2)" "unprognostic (1.87e-3)" "unprognostic (1.06e-1)" "unprognostic (6.87e-2)" GEN1 "FLJ40869, Gen" ENSG00000178295 "GEN1 Holliday junction 5' flap endonuclease" Q17RS7 2 17753858-17788946 "Predicted intracellular proteins" "DNA damage, DNA repair" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.3" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 268.8;Monocyte progenitors: 84.8;Retinal pigment epithelial cells: 119.4;Sertoli cells: 82.3" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 193.4" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "choroid plexus: 35.9" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA020078, HPA021141" Uncertain Approved Nucleoplasm NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 36: Choroid plexus - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 2 Nucleoplasm "HPA020078: , HPA021141: " "unprognostic (1.44e-1)" "unprognostic (1.85e-1)" "unprognostic (7.81e-2)" "unprognostic (1.46e-2)" "unprognostic (1.95e-1)" "unprognostic (1.36e-2)" "unprognostic (1.85e-1)" "unprognostic (8.59e-2)" "unprognostic (2.59e-3)" "potential prognostic unfavorable (3.21e-4)" "unprognostic (3.56e-2)" "potential prognostic unfavorable (7.06e-4)" "unprognostic (1.35e-1)" "unprognostic (4.13e-3)" "unprognostic (2.79e-1)" "unprognostic (3.03e-3)" "unprognostic (1.25e-3)" "unprognostic (3.09e-3)" "unprognostic (2.14e-1)" "unprognostic (9.29e-2)" "unprognostic (1.19e-1)" "unprognostic (7.28e-2)" "unprognostic (2.39e-3)" "unprognostic (8.21e-2)" "unprognostic (1.93e-3)" "unprognostic (7.79e-2)" "unprognostic (2.73e-2)" "unprognostic (5.32e-2)" "unprognostic (3.03e-1)" "unprognostic (1.82e-1)" "unprognostic (1.07e-2)" GET1 "CHD5, WRB" ENSG00000182093 "Guided entry of tail-anchored proteins factor 1" O00258 21 39377698-39428528 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 135.4" "Cell type enhanced" "Detected in some" "Astrocytes: 24.1;Bergmann glia: 28.0;Brain excitatory neurons: 43.1;Brain inhibitory neurons: 45.1;Choroid plexus epithelial cells: 64.4;Early spermatids: 40.0;Ependymal cells: 83.9;Late spermatids: 22.1;Oligodendrocyte progenitor cells: 30.4;Oligodendrocytes: 54.7;Other brain neurons: 63.2;Podocytes: 63.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" HPA018527 Approved NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 21: Non-specific - Metabolism" "Cluster 3: Rhabdoid - Membrane components" "Cluster 98: Neurons - Neurotransmission & signaling" 32 "HPA018527: " "unprognostic (2.09e-2)" "unprognostic (8.00e-3)" "unprognostic (1.44e-1)" "unprognostic (3.52e-2)" "unprognostic (1.18e-1)" "unprognostic (1.30e-1)" "unprognostic (5.31e-3)" "unprognostic (2.73e-1)" "unprognostic (1.30e-3)" "potential prognostic favorable (3.28e-7)" "unprognostic (1.91e-1)" "unprognostic (4.86e-3)" "unprognostic (1.35e-1)" "unprognostic (2.41e-2)" "unprognostic (9.20e-2)" "unprognostic (3.55e-2)" "unprognostic (2.32e-1)" "unprognostic (1.31e-1)" "unprognostic (1.71e-1)" "unprognostic (1.95e-2)" "unprognostic (2.60e-1)" "unprognostic (1.74e-1)" "unprognostic (1.41e-1)" "unprognostic (2.82e-1)" "unprognostic (2.07e-3)" "unprognostic (1.18e-2)" "unprognostic (7.45e-2)" "unprognostic (5.50e-2)" "unprognostic (5.18e-2)" GET1-SH3BGR ENSG00000285815 "GET1-SH3BGR readthrough" 21 39380332-39515506 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "retina: 5.4" "Cell type enriched" "Detected in many" 5 "Rod photoreceptor cells: 90.0" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 3.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 4.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in some" HPA018527 Uncertain NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 11: White matter - Signal transduction" "Cluster 61: BICR 18 - Protein kinases" "Cluster 79: Photoreceptor cells - Phototransduction" "HPA018527: " "unprognostic (9.50e-2)" "unprognostic (6.17e-3)" "potential prognostic favorable (2.96e-4)" "unprognostic (3.28e-2)" GET3 "ARSA-I, ASNA1, TRC40" ENSG00000198356 "Guided entry of tail-anchored proteins factor 3, ATPase" O43681 19 12737139-12748323 "Essential proteins, Predicted intracellular proteins, Transporters" Transport Hydrolase "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 196.3;Esophageal suprabasal cells: 190.5;Late spermatids: 293.0;Oocytes: 193.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045951, HPA048087" Approved Enhanced Nucleoplasm,Nucleoli NA NA 20000 "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 23: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 56 Nucleoli Nucleoplasm "HPA045951: , HPA048087: " "unprognostic (8.32e-2)" "unprognostic (6.88e-2)" "unprognostic (4.14e-2)" "unprognostic (2.31e-1)" "unprognostic (1.34e-1)" "unprognostic (7.82e-2)" "unprognostic (2.09e-1)" "unprognostic (1.18e-1)" "unprognostic (2.50e-3)" "potential prognostic favorable (2.37e-8)" "unprognostic (1.97e-1)" "unprognostic (8.95e-3)" "unprognostic (2.86e-3)" "unprognostic (2.35e-1)" "unprognostic (7.53e-2)" "unprognostic (2.04e-3)" "unprognostic (3.35e-1)" "unprognostic (4.39e-3)" "unprognostic (3.10e-2)" "unprognostic (2.88e-1)" "unprognostic (4.72e-1)" "unprognostic (3.24e-2)" "unprognostic (1.33e-1)" "unprognostic (1.42e-1)" "unprognostic (2.46e-1)" "unprognostic (1.55e-1)" "unprognostic (5.44e-2)" "unprognostic (4.53e-2)" "unprognostic (9.16e-2)" GET4 "C7orf20, CEE, CGI-20, H_NH1244M04.5, TRC35" ENSG00000239857 "Guided entry of tail-anchored proteins factor 4" Q7L5D6 7 876554-896436 "Predicted intracellular proteins" Transport "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Astrocytes: 25.0;Bergmann glia: 19.4;Brain excitatory neurons: 14.6;Brain inhibitory neurons: 13.5;Choroid plexus epithelial cells: 11.2;Ependymal cells: 14.5;Microglia: 16.1;Oligodendrocyte progenitor cells: 13.4;Oligodendrocytes: 27.1;Other brain neurons: 18.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019765 Uncertain Approved "Nucleoplasm,Nucleoli,Mitotic chromosome,Cytosol" Yes No "Cluster 25: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 6: Non-specific - Immune response" "Cluster 67: Non-specific - Unknown function" "Cluster 22: Non-specific - Basic cellular functions" 48 "Nucleoli, Cytosol" "Nucleoplasm, Mitotic chromosome" "HPA019765: " "unprognostic (2.10e-1)" "unprognostic (2.96e-2)" "unprognostic (1.03e-1)" "unprognostic (5.59e-2)" "unprognostic (3.51e-3)" "unprognostic (1.54e-1)" "unprognostic (1.30e-2)" "unprognostic (2.13e-1)" "unprognostic (3.22e-3)" "unprognostic (1.59e-2)" "unprognostic (5.38e-2)" "unprognostic (3.63e-1)" "unprognostic (9.09e-2)" "unprognostic (1.94e-2)" "unprognostic (3.66e-3)" "unprognostic (7.42e-2)" "unprognostic (2.38e-2)" "unprognostic (7.21e-2)" "unprognostic (3.44e-1)" "unprognostic (8.27e-2)" "unprognostic (2.05e-1)" "unprognostic (3.38e-2)" "unprognostic (2.62e-3)" "unprognostic (1.04e-1)" "unprognostic (8.96e-2)" "unprognostic (3.18e-1)" "unprognostic (1.03e-1)" "unprognostic (2.53e-1)" "unprognostic (1.12e-1)" "potential prognostic unfavorable (8.35e-4)" "unprognostic (1.31e-2)" GFAP FLJ45472 ENSG00000131095 "Glial fibrillary acidic protein" P14136 17 44903159-44916937 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 15929.3" "Cell type enriched" "Detected in some" 4 "Astrocytes: 781.6" "Cell type enriched" "Detected in many" 5 "astrocyte: 1723.3" "Cancer enriched" "Detected in many" 369 "Glioblastoma Multiforme (TCGA): 6588.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 6.1" "Group enriched" "Detected in many" 5 "granulocytes: 6.1;NK-cells: 1.7" "Cancer enriched" "Detected in many" 46 "Brain cancer: 164.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000039, HPA056030, HPA063513" Enhanced Supported Supported "Intermediate filaments" No No 67000000 "Cluster 20: Non-specific - DNA binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 44: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 28: Astrocytes - Homeostasis & neuron support" 175 "Intermediate filaments" "CAB000039: , HPA056030: , HPA063513: " "unprognostic (2.28e-1)" "unprognostic (1.52e-1)" "unprognostic (1.39e-1)" "unprognostic (4.32e-2)" "unprognostic (1.84e-3)" "unprognostic (3.12e-1)" "unprognostic (3.20e-1)" "unprognostic (1.67e-2)" "unprognostic (1.14e-2)" "unprognostic (3.13e-2)" "potential prognostic unfavorable (9.72e-5)" "unprognostic (5.09e-1)" "unprognostic (6.66e-2)" "unprognostic (2.69e-1)" "unprognostic (1.46e-2)" "unprognostic (2.59e-3)" "unprognostic (1.03e-2)" "unprognostic (1.85e-1)" "unprognostic (9.44e-2)" "unprognostic (5.83e-3)" "unprognostic (2.62e-2)" "unprognostic (1.56e-1)" "unprognostic (1.37e-2)" "unprognostic (7.95e-3)" "unprognostic (3.59e-1)" "unprognostic (3.22e-1)" "unprognostic (7.73e-2)" GFER "ALR, ERV1, HERV1, HPO1, HPO2, HSS" ENSG00000127554 "Growth factor, augmenter of liver regeneration" P55789 16 1984193-1987749 "Disease related genes, Enzymes, Essential proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor, Oxidoreductase" "Cataract, Deafness, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 150.2;Early spermatids: 206.0;Enterocytes: 336.4;Late spermatids: 165.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041227, HPA063553" Approved Enhanced Mitochondria,Cytosol "Secreted to blood" "Growth factor" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 17 Cytosol Mitochondria "HPA041227: , HPA063553: " "unprognostic (1.68e-1)" "unprognostic (1.10e-1)" "unprognostic (4.78e-2)" "unprognostic (7.18e-2)" "unprognostic (2.74e-2)" "unprognostic (2.31e-1)" "unprognostic (1.84e-1)" "unprognostic (2.14e-2)" "unprognostic (2.71e-1)" "unprognostic (3.43e-1)" "unprognostic (4.31e-3)" "unprognostic (7.49e-3)" "unprognostic (1.72e-1)" "unprognostic (1.34e-2)" "unprognostic (4.27e-2)" "unprognostic (7.06e-2)" "unprognostic (5.25e-2)" "unprognostic (2.22e-1)" "unprognostic (1.08e-1)" "unprognostic (5.45e-2)" "unprognostic (3.56e-2)" "unprognostic (4.65e-2)" "unprognostic (1.94e-1)" "unprognostic (9.32e-2)" "unprognostic (1.42e-1)" "unprognostic (3.78e-2)" "unprognostic (6.31e-2)" "unprognostic (1.42e-1)" "unprognostic (2.79e-1)" "unprognostic (2.02e-1)" "unprognostic (8.68e-2)" GFI1 "GFI-1, GFI1A, ZNF163" ENSG00000162676 "Growth factor independent 1 transcriptional repressor" Q99684 1 92473043-92486925 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 75.8;lymphoid tissue: 44.1" "Cell type enhanced" "Detected in some" "Goblet cells: 20.8;Hematopoietic stem cells: 9.7;Innate lymphoid cells: 22.1;Mast cells: 10.7;Monocyte progenitors: 19.5;Neutrophil progenitors: 83.3;NK-cells: 21.4;Paneth cells: 23.2;Plasma cells: 9.6;T-cells: 23.1" "Cell type enriched" "Detected in single" 62 "leukocyte: 25.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "gdT-cell: 3.5" "Group enriched" "Detected in many" 6 "dendritic cells: 1.6;T-cells: 3.5" "Cancer enhanced" "Detected in many" "Leukemia: 89.5" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Prostate - T-cells, Stomach - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" CAB011197 Uncertain NA NA "Cluster 1: T-cells - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 8: Immune cells - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 13 "CAB011197: " "unprognostic (2.77e-1)" "unprognostic (2.96e-2)" "unprognostic (1.16e-1)" "unprognostic (1.26e-3)" "unprognostic (3.96e-2)" "unprognostic (1.28e-3)" "unprognostic (1.66e-2)" "unprognostic (1.71e-1)" "unprognostic (3.22e-2)" "unprognostic (6.69e-3)" "unprognostic (1.12e-1)" "unprognostic (5.43e-2)" "unprognostic (2.22e-1)" "unprognostic (8.09e-2)" "unprognostic (6.43e-2)" "unprognostic (3.02e-2)" "unprognostic (7.50e-2)" "unprognostic (2.33e-3)" "unprognostic (1.94e-1)" "unprognostic (2.04e-1)" GFI1B ZNF163B ENSG00000165702 "Growth factor independent 1B transcriptional repressor" Q5VTD9 9 132944000-132991687 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, DNA-binding, Repressor" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "bone marrow: 36.8" "Cell type enhanced" "Detected in some" "Early spermatids: 190.6;Erythrocyte progenitors: 140.5;Late spermatids: 83.8;Megakaryocyte progenitors: 81.1;Megakaryocytes: 327.6;Platelets: 456.8;Tuft cells: 46.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 19 "basophil: 195.8;eosinophil: 396.6" "Lineage enriched" "Detected in many" 26 "granulocytes: 396.6" "Cancer enriched" "Detected in some" 25 "Leukemia: 46.9" "Liver - Erythroid cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB004420, HPA006291" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 15: Bone marrow - Innate immune response" "Cluster 30: White matter - Myelination" "Cluster 47: Leukemia - Hemostasis" "Cluster 47: Platelets - Hemostasis" 27 "Nucleoplasm, Plasma membrane" "CAB004420: , HPA006291: " GFM1 "EFGM, EGF1, GFM, mtEF-G1" ENSG00000168827 "G elongation factor mitochondrial 1" Q96RP9 3 158644527-158695581 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Protein biosynthesis" "Elongation factor, Hydrolase" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epicardial cells: 313.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034764, HPA034765, HPA061405" Enhanced Approved Nucleoplasm,Mitochondria NA NA 43000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 76: Non-specific - Metabolism" "Cluster 31: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 33 Mitochondria Nucleoplasm "HPA034764: , HPA034765: , HPA061405: " "unprognostic (1.59e-1)" "unprognostic (1.67e-2)" "unprognostic (4.52e-2)" "unprognostic (4.02e-3)" "unprognostic (2.31e-2)" "unprognostic (3.39e-1)" "unprognostic (2.37e-1)" "unprognostic (1.33e-1)" "unprognostic (1.10e-1)" "unprognostic (2.40e-3)" "unprognostic (2.90e-3)" "unprognostic (1.14e-1)" "unprognostic (2.22e-1)" "unprognostic (2.42e-3)" "potential prognostic unfavorable (5.08e-4)" "unprognostic (1.35e-3)" "unprognostic (5.12e-3)" "unprognostic (6.95e-3)" "unprognostic (8.22e-2)" "unprognostic (1.79e-1)" "unprognostic (2.84e-3)" "unprognostic (3.94e-3)" "unprognostic (6.62e-2)" "unprognostic (2.45e-1)" "unprognostic (3.58e-1)" "unprognostic (2.08e-1)" "unprognostic (2.51e-1)" "unprognostic (5.81e-2)" "unprognostic (1.85e-1)" "unprognostic (7.47e-2)" "unprognostic (2.75e-1)" GFM2 "EF-G2mt, EFG2, FLJ21661" ENSG00000164347 "GTP dependent ribosome recycling factor mitochondrial 2" Q969S9 5 74721206-74767147 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Protein biosynthesis" Hydrolase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036863, HPA069871" Uncertain Approved "Nucleoplasm,Midbody ring,Mitochondria" Yes NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 76: Non-specific - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 7 Mitochondria "Nucleoplasm, Midbody ring" "HPA036863: , HPA069871: " "unprognostic (9.46e-2)" "unprognostic (3.15e-2)" "unprognostic (9.36e-2)" "unprognostic (1.80e-1)" "unprognostic (2.77e-1)" "unprognostic (3.29e-1)" "unprognostic (8.10e-2)" "unprognostic (1.98e-2)" "unprognostic (1.34e-2)" "unprognostic (2.32e-3)" "potential prognostic favorable (2.22e-7)" "unprognostic (6.77e-2)" "unprognostic (4.03e-2)" "unprognostic (4.13e-1)" "unprognostic (3.96e-1)" "unprognostic (3.42e-2)" "unprognostic (1.43e-2)" "unprognostic (7.84e-2)" "unprognostic (7.53e-2)" "unprognostic (8.73e-2)" "unprognostic (8.88e-3)" "unprognostic (8.75e-2)" "potential prognostic unfavorable (4.35e-4)" "unprognostic (5.72e-2)" "unprognostic (1.42e-2)" "unprognostic (2.39e-1)" "unprognostic (3.75e-1)" "unprognostic (4.67e-2)" "unprognostic (1.40e-1)" "unprognostic (3.76e-2)" "unprognostic (2.33e-1)" GFOD1 "ADG-90, C6orf114, FLJ20330" ENSG00000145990 "Glucose-fructose oxidoreductase domain containing 1" Q9NXC2 6 13357830-13487662 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 196.2;Corticotrophs: 163.6;Neutrophil progenitors: 186.0;NK-cells: 298.2;Vascular endothelial cells: 220.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "eosinophil: 15.5;NK-cell: 13.1" "Group enriched" "Detected in many" 5 "granulocytes: 15.5;NK-cells: 13.1" "Low cancer specificity" "Detected in many" "Adrenal gland - Endothelial cells, Breast - Adipocytes (Breast), Pituitary gland - Corticotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029096 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" "Secreted - unknown location" "No annotated function" No No "Cluster 45: Eosinophils - Unknown function" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 51: Neurons - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 22 "Nucleoplasm, Cytosol" "Plasma membrane" "HPA029096: " "unprognostic (2.58e-1)" "unprognostic (3.29e-2)" "unprognostic (2.62e-3)" "unprognostic (1.78e-1)" "unprognostic (1.06e-1)" "unprognostic (5.79e-2)" "unprognostic (3.77e-2)" "unprognostic (3.18e-2)" "unprognostic (5.50e-3)" "validated prognostic favorable (1.91e-7)" "validated prognostic favorable (2.48e-4)" "unprognostic (6.43e-3)" "unprognostic (2.04e-2)" "unprognostic (6.03e-2)" "unprognostic (5.52e-2)" "unprognostic (3.32e-1)" "unprognostic (1.48e-1)" "unprognostic (1.33e-1)" "unprognostic (8.40e-3)" "unprognostic (1.50e-2)" "unprognostic (1.64e-1)" "unprognostic (6.04e-2)" "unprognostic (8.72e-2)" "unprognostic (3.91e-3)" "unprognostic (8.57e-2)" "unprognostic (3.38e-2)" "unprognostic (1.65e-2)" "unprognostic (2.43e-1)" "unprognostic (1.43e-2)" GFOD2 "FLJ23802, MGC11335" ENSG00000141098 "Glucose-fructose oxidoreductase domain containing 2" Q3B7J2 16 67674531-67719339 "Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 58.6" "Cell type enhanced" "Detected in many" "Early spermatids: 111.8;Esophageal apical cells: 429.7;Neutrophil progenitors: 104.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Adrenal gland - Adrenal cortex cells, Pituitary gland - Corticotropes, Spleen - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040939, HPA041112" Uncertain Uncertain Nucleoplasm,Cytosol "Secreted to blood" Enzyme NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 64: Non-specific - Transcription" "Cluster 35: Non-specific - DNA binding" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 1 Nucleoplasm Cytosol "HPA040939: , HPA041112: " "unprognostic (3.12e-2)" "unprognostic (3.23e-2)" "unprognostic (2.84e-1)" "unprognostic (5.84e-2)" "unprognostic (2.58e-1)" "unprognostic (5.42e-2)" "unprognostic (1.07e-1)" "potential prognostic favorable (8.50e-5)" "unprognostic (2.42e-1)" "unprognostic (1.33e-1)" "validated prognostic favorable (9.22e-10)" "validated prognostic favorable (8.75e-4)" "unprognostic (2.06e-1)" "unprognostic (1.11e-1)" "unprognostic (3.39e-3)" "unprognostic (1.50e-2)" "unprognostic (5.71e-2)" "unprognostic (5.40e-2)" "unprognostic (2.37e-1)" "unprognostic (3.77e-2)" "unprognostic (1.78e-1)" "unprognostic (1.07e-2)" "unprognostic (1.49e-1)" "unprognostic (9.73e-2)" "unprognostic (1.52e-1)" "unprognostic (2.49e-1)" "unprognostic (1.41e-2)" "unprognostic (1.50e-1)" "unprognostic (1.59e-1)" "unprognostic (1.28e-1)" "unprognostic (1.51e-1)" GFPT1 "GFA, GFAT, GFAT1, GFPT" ENSG00000198380 "Glutamine--fructose-6-phosphate transaminase 1" Q06210 2 69319780-69387250 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms" "Aminotransferase, Transferase" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Goblet cells: 461.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047240 Approved "Nucleoplasm,Nucleoli,Nucleoli fibrillar center" NA NA 67000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 17: Intestine - Digestion" "Cluster 21: Non-specific - Metabolism" "Cluster 13: Non-specific - Mixed function" "Cluster 70: Intestinal goblet cells - Mucin production" 7 "Nucleoplasm, Nucleoli" "Nucleoli fibrillar center" "HPA047240: " "unprognostic (1.17e-2)" "unprognostic (1.08e-3)" "unprognostic (1.48e-1)" "unprognostic (3.77e-3)" "unprognostic (6.76e-3)" "unprognostic (9.24e-2)" "unprognostic (1.59e-1)" "unprognostic (3.61e-2)" "unprognostic (8.98e-2)" "unprognostic (9.19e-3)" "potential prognostic favorable (3.38e-6)" "unprognostic (2.13e-2)" "unprognostic (3.88e-3)" "unprognostic (2.96e-2)" "unprognostic (8.02e-2)" "unprognostic (5.45e-2)" "unprognostic (1.05e-1)" "unprognostic (1.55e-2)" "unprognostic (4.53e-2)" "unprognostic (5.53e-2)" "unprognostic (4.78e-3)" "unprognostic (8.94e-3)" "unprognostic (1.46e-1)" "unprognostic (1.74e-1)" "unprognostic (1.02e-1)" "potential prognostic unfavorable (2.12e-4)" "unprognostic (1.63e-1)" "unprognostic (8.35e-2)" "unprognostic (4.76e-1)" "unprognostic (8.47e-2)" "unprognostic (7.68e-2)" GFPT2 GFAT2 ENSG00000131459 "Glutamine-fructose-6-phosphate transaminase 2" O94808 5 180300698-180353336 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Aminotransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 107.6" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 207.8;Endometrial stromal cells: 138.2;Epicardial cells: 914.2;Fibro-adipogenic progenitors: 194.3;Fibroblasts: 281.4;Mesothelial cells: 421.9" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 32.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 3.5" "Lineage enriched" "Detected in single" 35 "T-cells: 3.5" "Cancer enhanced" "Detected in many" "Brain cancer: 39.9" "Pituitary gland - Endothelial cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056892, HPA059910" Uncertain Approved Vesicles NA NA "Cluster 1: T-cells - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 39: Astrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 103: Non-specific - Basic cellular processes" 14 Vesicles "HPA056892: , HPA059910: " "unprognostic (1.06e-1)" "unprognostic (3.16e-1)" "unprognostic (2.85e-2)" "unprognostic (2.10e-2)" "unprognostic (5.49e-3)" "unprognostic (8.87e-2)" "unprognostic (5.37e-2)" "unprognostic (1.69e-1)" "unprognostic (1.47e-3)" "unprognostic (1.41e-2)" "validated prognostic unfavorable (2.97e-8)" "validated prognostic unfavorable (6.06e-4)" "unprognostic (9.46e-3)" "unprognostic (8.64e-2)" "unprognostic (1.38e-1)" "unprognostic (1.66e-2)" "potential prognostic unfavorable (2.84e-4)" "unprognostic (1.27e-2)" "unprognostic (1.91e-3)" "unprognostic (3.81e-3)" "unprognostic (7.37e-3)" "unprognostic (9.81e-2)" "unprognostic (6.32e-3)" "unprognostic (4.72e-2)" "unprognostic (3.62e-2)" "potential prognostic favorable (9.01e-4)" "unprognostic (1.33e-1)" "potential prognostic unfavorable (7.49e-4)" "unprognostic (1.95e-1)" "potential prognostic unfavorable (7.83e-5)" "unprognostic (1.46e-2)" GFRA1 "GDNFR, GDNFRA, GFR-ALPHA-1, RET1L, RETL1, TRNR1" ENSG00000151892 "GDNF family receptor alpha 1" P56159 10 116056925-116276803 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 84.9;Fibro-adipogenic progenitors: 123.0;Fibroblasts: 86.9;Hepatocytes: 74.9;Mesothelial cells: 61.7;Myosatellite cells: 70.0;Oligodendrocyte progenitor cells: 160.7;Oocytes: 82.9;Pituicytes/FSCs: 419.3;Pituitary stem cells: 102.3;Retinal amacrine cells: 88.0;Salivary myoepithelial cells: 69.1;Schwann cells: 108.4;Undifferentiated spermatogonia: 83.6" "Cell type enhanced" "Detected in many" "eccentric medium spiny neuron: 189.2;oligodendrocyte precursor cell: 191.7" "Cancer enriched" "Detected in many" 11 "Breast Invasive Carcinoma (TCGA): 88.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 73.8" "Kidney - Fibroblasts, Prostate - Fibroblasts, Stomach - Fibroblasts, Testis - Spermatogonia, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043829 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA 69000 "Cluster 22: Epididymis - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 3 "Golgi apparatus" Nucleoplasm "HPA043829: " "unprognostic (6.12e-2)" "unprognostic (2.25e-1)" "unprognostic (6.55e-2)" "unprognostic (9.72e-2)" "potential prognostic favorable (6.83e-6)" "unprognostic (1.00e-3)" "unprognostic (2.02e-3)" "unprognostic (6.20e-2)" "unprognostic (1.58e-2)" "potential prognostic favorable (2.37e-5)" "unprognostic (3.35e-2)" "unprognostic (7.15e-2)" "unprognostic (6.99e-3)" "potential prognostic unfavorable (7.59e-5)" "unprognostic (2.04e-2)" "unprognostic (6.12e-2)" "unprognostic (2.20e-2)" "unprognostic (1.18e-2)" "unprognostic (4.03e-3)" "unprognostic (2.70e-3)" "unprognostic (1.74e-1)" "unprognostic (1.41e-2)" GFRA2 "GDNFRB, NTNRA, RETL2, TRNR2" ENSG00000168546 "GDNF family receptor alpha 2" O00451 8 21690398-21812357 "Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 9.0;thyroid gland: 8.2" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 74.5;cDC: 64.6;Early spermatids: 130.3;Epididymal efferent duct absorptive cells: 71.2;Kupffer cells: 92.2;Late spermatids: 422.3;Macrophages: 55.8;Retinal horizontal cells: 452.8" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Thyroid Carcinoma (TCGA): 4.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 9.3" "Group enriched" "Detected in many" 7 "dendritic cells: 2.5;monocytes: 9.3" "Cancer enriched" "Detected in some" 6 "Neuroblastoma: 59.7" "Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Liver - Kupffer cells, Skeletal muscle - Fibroblasts, Spleen - Macrophages, Stomach - Fibroblasts, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024704, CAB032791" Uncertain Approved "Vesicles,Plasma membrane" "Intracellular and membrane" Receptor NA NA 3100000 "Cluster 25: Non-specific - Unknown function" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 53: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 2 "Plasma membrane" Vesicles "CAB032791: , HPA024704: " "unprognostic (9.14e-2)" "unprognostic (3.62e-2)" "unprognostic (3.78e-1)" "potential prognostic favorable (9.97e-4)" "unprognostic (4.59e-3)" "unprognostic (6.73e-2)" "unprognostic (1.98e-1)" "unprognostic (4.35e-2)" "unprognostic (6.23e-2)" "unprognostic (1.32e-2)" GFRA3 GFRa-3 ENSG00000146013 "GDNF family receptor alpha 3" O60609 5 138252380-138274621 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 13.3" "Group enriched" "Detected in some" 6 "Late spermatids: 34.5;Neuroendocrine cells: 62.5;Oocytes: 50.7;Schwann cells: 74.9" "Cell type enhanced" "Detected in single" "upper rhombic lip: 3.1" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 18.0" "Region enriched" "Detected in single" 9 "cerebellum: 5.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 9 "Neuroblastoma: 14.9" "Adipose subcutaneous - Smooth muscle cells, Colon - Enteric glia cells, Minor Salivary Gland - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Gastric enteroendocrine cells, Thyroid gland - Fibroblasts" "Not detected" "Not detected" "Region enriched" "Detected in all" 6 "spinal cord: 41.1" HPA020731 Approved Supported "Plasma membrane,Cytosol" NA NA 120000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 35: Non-specific - DNA binding" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" 1 "Plasma membrane" Cytosol "HPA020731: " "unprognostic (5.68e-2)" "unprognostic (1.29e-1)" "unprognostic (1.38e-1)" "unprognostic (5.09e-2)" "unprognostic (6.00e-2)" "potential prognostic favorable (2.00e-4)" "unprognostic (3.01e-2)" "unprognostic (3.36e-1)" "unprognostic (6.53e-2)" "unprognostic (5.40e-2)" "unprognostic (7.03e-2)" "unprognostic (9.01e-3)" "unprognostic (8.23e-2)" "unprognostic (1.65e-1)" "unprognostic (1.04e-2)" "unprognostic (4.56e-1)" "unprognostic (1.95e-2)" GFRA4 ENSG00000125861 "GDNF family receptor alpha 4" Q9GZZ7 20 3659248-3663399 "Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "thyroid gland: 1.0" "Cell type enhanced" "Detected in some" "Early spermatids: 1.3;Late spermatids: 5.1;Smooth muscle cells: 2.7" "Cell type enhanced" "Detected in single" "deep-layer near-projecting: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 96 "thyroid cancer: 10.0" "Thyroid gland - Parafollicular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Intracellular and membrane" Receptor NA NA "Cluster 33: Thyroid gland - Tissue development" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 98: Neurons - Neurotransmission & signaling" GFRAL "bA360D14.1, C6orf144, GRAL, UNQ9356" ENSG00000187871 "GDNF family receptor alpha like" Q6UXV0 6 55327469-55402493 "Predicted membrane proteins" "Hormone, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Bergmann glia: 4.8;Epicardial cells: 4.5;Fibro-adipogenic progenitors: 9.9;Hepatic stellate cells: 6.5;Pericytes: 3.0;Pituitary stem cells: 4.2;Retinal amacrine cells: 2.6;Undifferentiated spermatogonia: 2.9" "Cell type enhanced" "Detected in many" "Bergmann glia: 4.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA047372 Uncertain Approved "Nucleoplasm,Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 15: Non-specific - Transcription" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 1 "Nucleoplasm, Plasma membrane" "Actin filaments, Focal adhesion sites" "HPA047372: " GFUS "FX, P35B, SDR4E1, TSTA3" ENSG00000104522 "GDP-L-fucose synthase" Q13630 8 143612618-143618048 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Multifunctional enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 184.3;Gastric chief cells: 131.0;Late primary spermatocytes: 70.4;Late spermatids: 241.4;Suprabasal keratinocytes: 64.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023361 Approved Approved Nucleoplasm,Cytosol Yes No 1100000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 70: Non-specific - Protein processing" "Cluster 45: Non-specific - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 3 Cytosol Nucleoplasm "HPA023361: " "unprognostic (2.45e-1)" "unprognostic (2.66e-2)" "unprognostic (2.10e-2)" "unprognostic (1.15e-1)" "unprognostic (1.42e-2)" "unprognostic (2.26e-1)" "unprognostic (5.08e-2)" "unprognostic (2.46e-2)" "unprognostic (6.83e-2)" "potential prognostic unfavorable (1.08e-5)" "unprognostic (1.25e-3)" "unprognostic (1.39e-1)" "unprognostic (7.14e-2)" "unprognostic (9.90e-2)" "unprognostic (5.31e-2)" "unprognostic (1.22e-2)" "unprognostic (4.67e-2)" "unprognostic (1.02e-2)" "unprognostic (3.32e-1)" "unprognostic (2.25e-3)" "unprognostic (5.24e-2)" "unprognostic (5.20e-1)" "unprognostic (4.14e-2)" "unprognostic (1.31e-3)" "unprognostic (1.06e-1)" "unprognostic (3.51e-2)" "unprognostic (1.59e-1)" "unprognostic (1.43e-1)" "unprognostic (1.25e-1)" GFY Goofy ENSG00000261949 "Golgi associated olfactory signaling regulator" I3L273 19 49423749-49428987 "Predicted membrane proteins" "Olfaction, Sensory transduction" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in single" "testis: 1.3" "Cell type enriched" "Detected in some" 10 "Oocytes: 18.4" "Cell type enhanced" "Detected in some" "deep-layer near-projecting: 1.2;lower rhombic lip: 1.2" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 1.6" "Region enhanced" "Detected in single" "cerebellum: 2.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Rhabdoid: 13.5" "Testis - Late spermatids" "Region enriched" "Detected in single" 13 "olfactory bulb: 1.4" "Region enriched" "Detected in some" 7 "cerebellum: 7.9" NA NA "Cluster 67: Testis - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 41: Oocytes - Oogenesis" "unprognostic (5.59e-3)" "unprognostic (2.05e-1)" "unprognostic (1.28e-1)" GGA1 ENSG00000100083 "Golgi associated, gamma adaptin ear containing, ARF binding protein 1" Q9UJY5 22 37608725-37633564 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 176.9" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 171.4;Late primary spermatocytes: 238.7;Late spermatids: 304.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048280, HPA051016" Supported Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 67: Testis - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 66: Non-specific - Mitochondria" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 53 "Golgi apparatus, Vesicles" Nucleoplasm "HPA048280: , HPA051016: " "unprognostic (1.45e-1)" "unprognostic (1.19e-1)" "unprognostic (8.44e-2)" "unprognostic (1.83e-1)" "unprognostic (8.90e-2)" "unprognostic (2.15e-1)" "unprognostic (2.21e-1)" "unprognostic (7.52e-2)" "unprognostic (1.01e-1)" "unprognostic (1.62e-1)" "unprognostic (2.66e-1)" "unprognostic (7.56e-2)" "potential prognostic favorable (5.98e-5)" "potential prognostic unfavorable (3.17e-6)" "unprognostic (2.13e-1)" "unprognostic (2.47e-2)" "unprognostic (1.38e-1)" "unprognostic (1.27e-1)" "unprognostic (5.53e-3)" "unprognostic (3.59e-1)" "unprognostic (1.18e-2)" "unprognostic (3.30e-3)" "unprognostic (4.07e-3)" "unprognostic (2.56e-2)" "unprognostic (1.62e-1)" "unprognostic (5.73e-2)" "unprognostic (2.51e-1)" "unprognostic (1.20e-1)" "unprognostic (2.69e-1)" "unprognostic (1.38e-2)" "unprognostic (6.01e-2)" GGA2 "KIAA1080, VEAR" ENSG00000103365 "Golgi associated, gamma adaptin ear containing, ARF binding protein 2" Q9UJY4 16 23463542-23521995 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Retinal pigment epithelial cells: 264.3;Rod photoreceptor cells: 405.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate basal glandular cells, Spleen - B-cells (Spleen), Stomach - Parietal cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB034422, HPA043313, HPA063634" Approved Enhanced "Golgi apparatus" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 23: Choroid plexus - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 38 "Golgi apparatus" "CAB034422: , HPA043313: , HPA063634: " "unprognostic (9.24e-2)" "unprognostic (1.97e-1)" "unprognostic (4.80e-2)" "unprognostic (3.26e-2)" "unprognostic (3.82e-2)" "unprognostic (1.16e-1)" "unprognostic (4.40e-3)" "unprognostic (6.26e-3)" "potential prognostic favorable (4.19e-4)" "unprognostic (1.13e-1)" "potential prognostic favorable (2.54e-4)" "unprognostic (1.06e-1)" "unprognostic (3.55e-2)" "unprognostic (8.42e-2)" "unprognostic (5.04e-2)" "unprognostic (5.58e-3)" "unprognostic (5.09e-2)" "unprognostic (1.19e-1)" "unprognostic (1.02e-1)" "unprognostic (1.41e-1)" "unprognostic (1.12e-1)" "unprognostic (1.31e-2)" "potential prognostic unfavorable (2.39e-4)" "unprognostic (4.96e-2)" "unprognostic (6.60e-2)" "unprognostic (3.78e-2)" "unprognostic (6.00e-3)" "unprognostic (3.34e-2)" "unprognostic (9.28e-2)" "unprognostic (2.67e-1)" "unprognostic (3.85e-2)" GGA3 KIAA0154 ENSG00000125447 "Golgi associated, gamma adaptin ear containing, ARF binding protein 3" Q9NZ52 17 75236599-75262363 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 153.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022945, HPA024645" Approved Supported "Golgi apparatus" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 41 "Golgi apparatus" "HPA022945: , HPA024645: " "unprognostic (1.41e-1)" "unprognostic (3.71e-1)" "unprognostic (1.06e-2)" "unprognostic (8.82e-3)" "unprognostic (4.77e-3)" "unprognostic (7.72e-2)" "unprognostic (2.13e-1)" "unprognostic (3.23e-2)" "unprognostic (1.64e-1)" "potential prognostic unfavorable (3.32e-4)" "potential prognostic favorable (4.68e-4)" "unprognostic (4.57e-2)" "unprognostic (9.54e-2)" "potential prognostic unfavorable (5.46e-5)" "unprognostic (5.34e-2)" "unprognostic (1.55e-1)" "unprognostic (1.56e-1)" "unprognostic (1.34e-2)" "unprognostic (1.74e-1)" "unprognostic (2.14e-1)" "unprognostic (3.96e-3)" "unprognostic (1.15e-2)" "potential prognostic unfavorable (8.63e-4)" "unprognostic (1.35e-1)" "unprognostic (2.12e-2)" "unprognostic (3.40e-3)" "unprognostic (1.20e-1)" "unprognostic (9.09e-2)" "unprognostic (5.32e-2)" "unprognostic (2.46e-2)" "unprognostic (2.97e-2)" GGACT A2LD1 ENSG00000134864 "Gamma-glutamylamine cyclotransferase" Q9BVM4 13 100530164-100589528 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "kidney: 67.5" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 24.2;Epididymal efferent duct absorptive cells: 22.9;Loop of henle epithelial cells: 22.2;Oocytes: 27.6;Papillary tip epithelial cells: 39.4;Proximal tubule cells: 41.9;Renal collecting duct principal cells: 33.9" "Cell type enhanced" "Detected in some" "Bergmann glia: 4.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065320 Enhanced NA NA 28000 "Cluster 33: Non-specific - ATP binding" "Cluster 72: Kidney - Transmembrane transport" "Cluster 19: Astrocytes - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 6 "HPA065320: " "unprognostic (3.53e-1)" "unprognostic (5.53e-2)" "unprognostic (1.07e-2)" "unprognostic (3.91e-2)" "unprognostic (1.82e-1)" "unprognostic (4.30e-3)" "potential prognostic unfavorable (8.33e-5)" "unprognostic (9.04e-2)" "unprognostic (5.78e-2)" "potential prognostic favorable (6.25e-6)" "unprognostic (2.20e-1)" "unprognostic (1.07e-1)" "unprognostic (2.48e-2)" "unprognostic (1.70e-3)" "unprognostic (7.84e-2)" "unprognostic (1.72e-1)" "unprognostic (6.03e-2)" "unprognostic (1.00e-1)" "unprognostic (1.11e-1)" "unprognostic (1.71e-2)" "unprognostic (1.69e-2)" "unprognostic (7.31e-2)" "unprognostic (2.39e-2)" "unprognostic (4.45e-2)" "unprognostic (9.99e-3)" "unprognostic (1.71e-1)" "unprognostic (2.54e-1)" "unprognostic (8.18e-2)" "unprognostic (8.33e-2)" GGCT "C7orf24, CRF21, GCTG, Ggc, MGC3077" ENSG00000006625 Gamma-glutamylcyclotransferase O75223 7 30496621-30504841 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 501.9;Epididymal principal cells: 341.4;Esophageal apical cells: 348.6;Esophageal basal cells: 302.6;Esophageal suprabasal cells: 386.5;Gastric progenitor cells: 252.5;Migrating cytotrophoblasts: 357.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020735, HPA029914" Approved NA Yes 3000000 "Cluster 13: Non-specific - Mitochondria" "Cluster 58: Skin - Keratinization" "Cluster 14: Neurons - Synaptic function" "Cluster 67: Non-specific - Unknown function" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 5 "HPA020735: , HPA029914: " "unprognostic (1.45e-1)" "potential prognostic unfavorable (4.28e-4)" "unprognostic (1.06e-1)" "unprognostic (1.99e-1)" "unprognostic (6.08e-3)" "unprognostic (3.17e-2)" "unprognostic (1.45e-1)" "unprognostic (5.80e-2)" "unprognostic (1.37e-2)" "unprognostic (6.37e-3)" "unprognostic (5.36e-3)" "unprognostic (5.33e-2)" "unprognostic (1.80e-1)" "validated prognostic unfavorable (1.53e-4)" "validated prognostic unfavorable (1.44e-9)" "unprognostic (4.01e-2)" "unprognostic (5.75e-3)" "potential prognostic favorable (7.59e-4)" "unprognostic (1.20e-1)" "unprognostic (1.54e-1)" "unprognostic (4.75e-1)" "unprognostic (5.04e-3)" "unprognostic (1.12e-1)" "unprognostic (2.05e-1)" "unprognostic (1.09e-1)" "unprognostic (2.03e-1)" "unprognostic (3.12e-3)" "unprognostic (2.27e-1)" "unprognostic (1.07e-1)" "unprognostic (2.76e-3)" "unprognostic (3.88e-2)" GGCX VKCFD1 ENSG00000115486 "Gamma-glutamyl carboxylase" P38435 2 85544720-85561532 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Lyase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "liver: 100.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 193.6;Epicardial cells: 491.2;Hepatocytes: 181.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018284 Enhanced NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 45: Non-specific - Nuclear processes" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 23 "HPA018284: " "unprognostic (1.61e-1)" "unprognostic (1.75e-3)" "unprognostic (1.98e-1)" "unprognostic (6.44e-3)" "unprognostic (2.86e-1)" "unprognostic (2.81e-3)" "unprognostic (1.46e-1)" "unprognostic (6.22e-2)" "unprognostic (4.16e-2)" "unprognostic (1.16e-1)" "potential prognostic favorable (7.75e-4)" "unprognostic (1.72e-1)" "unprognostic (3.27e-2)" "unprognostic (2.86e-2)" "unprognostic (3.96e-2)" "unprognostic (3.95e-2)" "unprognostic (6.27e-2)" "unprognostic (4.59e-2)" "unprognostic (6.63e-2)" "potential prognostic unfavorable (6.41e-5)" "unprognostic (2.32e-2)" "potential prognostic unfavorable (1.75e-4)" "unprognostic (4.03e-2)" "unprognostic (2.78e-1)" "unprognostic (9.31e-3)" "unprognostic (7.98e-2)" "unprognostic (5.33e-2)" "unprognostic (8.04e-2)" "unprognostic (1.89e-1)" "unprognostic (1.16e-1)" "unprognostic (9.29e-2)" GGH GATD10 ENSG00000137563 "Gamma-glutamyl hydrolase" Q92820 8 63014881-63039407 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 117.3;liver: 176.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 652.2;Differentiating spermatogonia: 176.0;Early spermatids: 531.8;Extravillous trophoblasts: 371.8;Hepatocytes: 214.1;Late primary spermatocytes: 180.3;Late spermatids: 184.8;Migrating cytotrophoblasts: 251.5;Oocytes: 336.2;Syncytiotrophoblasts: 882.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "plasmacytoid DC: 30.6" "Lineage enriched" "Detected in all" 5 "dendritic cells: 30.6" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019296, HPA025226" Approved Supported "Endoplasmic reticulum,Vesicles" "Intracellular and membrane" Enzyme NA NA 400000000 "Cluster 13: Non-specific - Mitochondria" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 24: Neurons - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 114 Vesicles "Endoplasmic reticulum" "CAB019296: , HPA025226: " "unprognostic (5.75e-3)" "unprognostic (4.76e-2)" "unprognostic (1.03e-1)" "unprognostic (1.18e-1)" "unprognostic (8.79e-2)" "unprognostic (1.18e-3)" "unprognostic (4.32e-2)" "unprognostic (1.66e-1)" "unprognostic (5.44e-2)" "unprognostic (3.35e-3)" "potential prognostic favorable (8.01e-4)" "unprognostic (2.61e-2)" "unprognostic (1.50e-2)" "unprognostic (1.37e-1)" "unprognostic (2.52e-1)" "potential prognostic unfavorable (1.62e-4)" "unprognostic (1.49e-1)" "unprognostic (4.66e-1)" "unprognostic (5.03e-2)" "unprognostic (2.44e-2)" "unprognostic (1.90e-2)" "unprognostic (3.89e-2)" "potential prognostic unfavorable (5.81e-4)" "unprognostic (9.72e-2)" "unprognostic (4.59e-2)" "unprognostic (2.27e-2)" "unprognostic (2.07e-3)" "unprognostic (1.29e-2)" "unprognostic (1.74e-1)" "unprognostic (1.39e-1)" "unprognostic (6.85e-2)" GGN "FLJ35713, MGC33369" ENSG00000179168 Gametogenetin Q86UU5 19 38384267-38388082 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 33 "testis: 90.1" "Group enriched" "Detected in some" 36 "Early spermatids: 536.8;Late primary spermatocytes: 578.2;Late spermatids: 1224.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA078224 Approved "Golgi apparatus,Cytosol" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 79: Testis - Spermatogenesis" "Cluster 6: Non-specific - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 15 "Golgi apparatus" Cytosol "HPA078224: " "unprognostic (1.86e-2)" "unprognostic (4.53e-1)" "unprognostic (2.08e-2)" "unprognostic (5.85e-3)" "unprognostic (2.51e-1)" "unprognostic (1.37e-2)" GGNBP2 "DIF-3, DIF3, FLJ21230, FLJ22561, LZK1, ZFP403, ZNF403" ENSG00000278311 "Gametogenetin binding protein 2" Q9H3C7 17 36544912-36589848 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 332.6;Late primary spermatocytes: 577.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018914, HPA073392" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 39: Testis - Nuclear processes" "Cluster 25: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 102: Non-specific - Mixed function" 2 "Endoplasmic reticulum" "HPA018914: , HPA073392: " "unprognostic (3.86e-2)" "unprognostic (2.89e-2)" "unprognostic (1.29e-1)" "unprognostic (6.93e-2)" "unprognostic (2.08e-1)" "unprognostic (3.14e-2)" "unprognostic (1.69e-1)" "unprognostic (2.87e-1)" "unprognostic (3.87e-2)" "validated prognostic favorable (4.16e-6)" "validated prognostic favorable (4.51e-4)" "unprognostic (9.75e-3)" "unprognostic (4.51e-3)" "unprognostic (2.75e-2)" "unprognostic (1.63e-2)" "unprognostic (1.62e-1)" "unprognostic (1.94e-1)" "unprognostic (8.53e-2)" "unprognostic (3.50e-3)" "unprognostic (1.00e-1)" "unprognostic (6.26e-2)" "potential prognostic favorable (9.76e-4)" "unprognostic (2.06e-1)" "unprognostic (1.03e-1)" "unprognostic (1.29e-1)" "unprognostic (5.63e-2)" "unprognostic (1.75e-1)" "unprognostic (1.82e-1)" GGPS1 GGPPS1 ENSG00000152904 "Geranylgeranyl diphosphate synthase 1" O95749 1 235327350-235344532 "Disease related genes, Enzymes, Essential proteins, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Isoprene biosynthesis, Lipid metabolism" Transferase "Congenital muscular dystrophy, Deafness, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 197.6;Early spermatids: 117.6;Epicardial cells: 332.0;Late primary spermatocytes: 101.7;Late spermatids: 884.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029472, HPA050727" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 10 Cytosol Nucleoplasm "HPA029472: , HPA050727: " "unprognostic (1.66e-1)" "unprognostic (2.28e-2)" "unprognostic (1.07e-1)" "unprognostic (3.78e-2)" "unprognostic (2.26e-1)" "unprognostic (9.98e-2)" "unprognostic (2.80e-1)" "unprognostic (1.69e-1)" "unprognostic (1.50e-2)" "unprognostic (5.91e-3)" "potential prognostic favorable (1.08e-4)" "unprognostic (1.83e-1)" "unprognostic (2.72e-1)" "unprognostic (1.10e-3)" "unprognostic (1.22e-1)" "unprognostic (9.58e-3)" "unprognostic (5.97e-2)" "unprognostic (3.17e-2)" "unprognostic (2.64e-1)" "unprognostic (2.39e-2)" "unprognostic (9.75e-2)" "unprognostic (2.89e-2)" "unprognostic (2.68e-1)" "unprognostic (3.55e-2)" "unprognostic (1.25e-2)" "unprognostic (3.30e-2)" "unprognostic (2.88e-3)" "unprognostic (3.02e-2)" "unprognostic (2.59e-2)" "unprognostic (1.10e-1)" "unprognostic (1.85e-1)" GGT1 "CD224, D22S672, D22S732, GGT" ENSG00000100031 "Gamma-glutamyltransferase 1" P19440 22 24594811-24629005 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glutathione biosynthesis, Lipid metabolism" "Acyltransferase, Hydrolase, Protease, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 149.7;liver: 103.5" "Cell type enhanced" "Detected in some" "Colonocytes: 22.4;Distal convoluted tubule cells: 11.5;Enterocytes: 49.3;Epididymal principal cells: 30.3;Gastric chief cells: 15.3;Loop of henle epithelial cells: 16.0;Proximal tubule cells: 128.8" "Group enriched" "Detected in some" 5 "fibroblast: 2.3;pericyte: 5.9" "Cancer enhanced" "Detected in all" "Kidney Renal Papillary Cell Carcinoma (TCGA): 231.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Kidney cancer: 119.6" "Adrenal gland - Fibroblasts, Kidney - Proximal tubular cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045635, HPA047534, HPA065444" Supported Uncertain Vesicles "Intracellular and membrane" Enzyme NA NA 3400000 "Cluster 28: Neutrophils - Unknown function" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 30: White matter - Myelination" "Cluster 15: Kidney cancer - Membrane components" "Cluster 88: Proximal tubular cells - Transmembrane transport" 4 Vesicles "HPA045635: , HPA047534: , HPA065444: " "potential prognostic unfavorable (6.50e-8)" "unprognostic (1.36e-3)" "unprognostic (6.84e-3)" "unprognostic (7.62e-2)" "unprognostic (8.29e-2)" "unprognostic (7.51e-3)" "unprognostic (6.17e-3)" "potential prognostic favorable (9.95e-4)" "unprognostic (2.28e-3)" "unprognostic (4.79e-1)" "potential prognostic favorable (1.44e-4)" "unprognostic (1.72e-1)" "unprognostic (1.88e-3)" "unprognostic (5.57e-3)" "unprognostic (9.20e-3)" "unprognostic (5.97e-3)" "unprognostic (1.01e-1)" "unprognostic (3.60e-2)" "unprognostic (1.59e-2)" "unprognostic (1.96e-2)" "unprognostic (1.09e-1)" "unprognostic (5.16e-2)" "unprognostic (1.09e-1)" "unprognostic (9.37e-2)" "unprognostic (2.60e-1)" "unprognostic (3.01e-1)" "unprognostic (1.02e-2)" "unprognostic (1.06e-2)" "unprognostic (8.62e-2)" "unprognostic (2.45e-1)" "unprognostic (3.13e-1)" GGT5 "GGT-REL, GGTLA1" ENSG00000099998 "Gamma-glutamyltransferase 5" P36269 22 24219654-24245108 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glutathione biosynthesis, Leukotriene biosynthesis" "Acyltransferase, Hydrolase, Protease, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 62.7;Fibroblasts: 104.9;Hepatic stellate cells: 374.4;Leydig cells: 37.9;Lymphatic endothelial cells: 114.0;Myosatellite cells: 40.3;Pericytes: 241.6;Pituicytes/FSCs: 47.3;Vascular endothelial cells: 51.1;Vascular smooth muscle cells: 36.4" "Cell type enriched" "Detected in some" 4 "pericyte: 440.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.3;eosinophil: 4.5" "Lineage enriched" "Detected in single" 8 "granulocytes: 4.5" "Cancer enhanced" "Detected in many" "testis cancer: 62.1" "Adrenal gland - Fibroblasts, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Testis - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008121, CAB032489" Uncertain Approved "Nucleoli fibrillar center" NA NA 2300000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 110: Mural cells - ECM organization" "Nucleoli fibrillar center" "CAB032489: , HPA008121: " "unprognostic (7.81e-2)" "unprognostic (7.94e-2)" "unprognostic (3.35e-2)" "unprognostic (2.12e-1)" "unprognostic (9.28e-3)" "unprognostic (7.32e-3)" "unprognostic (9.41e-2)" "unprognostic (6.81e-3)" "unprognostic (2.01e-1)" "unprognostic (1.04e-1)" "unprognostic (1.77e-1)" "unprognostic (5.73e-3)" "unprognostic (3.70e-3)" "unprognostic (3.76e-2)" "potential prognostic favorable (1.93e-4)" "unprognostic (2.73e-2)" "unprognostic (3.69e-2)" "unprognostic (1.10e-1)" "unprognostic (3.13e-2)" "unprognostic (5.84e-3)" "unprognostic (2.78e-2)" "unprognostic (4.06e-1)" "unprognostic (1.45e-1)" "unprognostic (6.41e-2)" "unprognostic (6.06e-2)" "unprognostic (1.74e-2)" "unprognostic (8.83e-2)" "potential prognostic unfavorable (3.38e-4)" "unprognostic (2.25e-3)" "unprognostic (1.08e-1)" "unprognostic (2.62e-2)" GGT6 FLJ90165 ENSG00000167741 "Gamma-glutamyltransferase 6" Q6P531 17 4556927-4560818 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glutathione biosynthesis" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 49.6;intestine: 50.0;salivary gland: 52.6;skin 1: 51.2" "Cell type enhanced" "Detected in many" "Colonocytes: 177.1;Enteric stem cells: 67.9;Enteric transient amplifying cells: 86.6;Enterocytes: 110.7;Epididymal principal cells: 92.6;Esophageal apical cells: 328.8;Esophageal suprabasal cells: 118.4;Goblet cells: 71.0;Prostatic club cells: 67.2;Prostatic hillock cells: 85.9;Salivary duct cells: 76.4;Urothelial cells: 80.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 14.1;colorectal cancer: 19.1;Gallbladder cancer: 13.9" "Colon - Colon enterocytes, Liver - Cholangiocytes, Pituitary gland - Gonadotropes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA023362, HPA027213" Approved Approved Cytosol NA NA 61000 "Cluster 60: Stomach - Digestion" "Cluster 9: Non-specific - Receptor signaling" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 6 Cytosol "HPA023362: , HPA027213: " "potential prognostic favorable (5.05e-5)" "unprognostic (6.15e-3)" "unprognostic (6.49e-2)" "unprognostic (8.18e-2)" "unprognostic (6.45e-3)" "potential prognostic favorable (8.77e-4)" "unprognostic (4.23e-2)" "unprognostic (2.24e-1)" "unprognostic (5.72e-2)" "unprognostic (5.80e-2)" "unprognostic (4.01e-2)" "unprognostic (2.05e-1)" "potential prognostic favorable (1.02e-4)" "unprognostic (2.48e-2)" "unprognostic (1.07e-1)" "unprognostic (3.99e-1)" "unprognostic (3.36e-1)" "unprognostic (1.25e-1)" "unprognostic (2.53e-2)" "unprognostic (7.58e-2)" "unprognostic (4.85e-2)" "unprognostic (1.41e-1)" "unprognostic (8.23e-3)" "unprognostic (6.68e-2)" "unprognostic (1.29e-1)" "unprognostic (8.25e-2)" "unprognostic (1.56e-1)" "unprognostic (9.35e-2)" GGT7 "D20S101, dJ18C9.2, GGTL3, GGTL5" ENSG00000131067 "Gamma-glutamyltransferase 7" Q9UJ14 20 34844720-34872856 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glutathione biosynthesis" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Retinal ganglion cells: 158.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013204, HPA013339" Approved Approved Nucleoplasm,Vesicles NA NA 650000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 13 Vesicles Nucleoplasm "HPA013204: , HPA013339: " "unprognostic (1.06e-1)" "unprognostic (9.81e-3)" "unprognostic (3.65e-1)" "unprognostic (6.69e-2)" "unprognostic (7.59e-2)" "unprognostic (1.05e-2)" "unprognostic (9.94e-2)" "unprognostic (1.45e-2)" "unprognostic (3.32e-2)" "potential prognostic unfavorable (2.69e-4)" "unprognostic (4.07e-2)" "unprognostic (1.00e-2)" "unprognostic (3.00e-2)" "potential prognostic unfavorable (1.21e-4)" "unprognostic (4.85e-2)" "unprognostic (6.15e-2)" "unprognostic (2.21e-1)" "unprognostic (4.61e-1)" "unprognostic (8.19e-3)" "unprognostic (3.78e-2)" "unprognostic (1.76e-1)" "unprognostic (1.79e-3)" "unprognostic (9.07e-3)" "unprognostic (5.38e-2)" "unprognostic (1.10e-2)" "unprognostic (1.97e-1)" "unprognostic (3.05e-2)" "unprognostic (9.24e-2)" "unprognostic (3.52e-2)" "unprognostic (7.60e-2)" "unprognostic (3.70e-2)" GGTA1 "GGTA, GGTA1P, GLYT2" ENSG00000204136 "Glycoprotein alpha-galactosyltransferase 1 (inactive)" Q4G0N0 9 121444991-121499844 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 87.5;salivary gland: 125.4" "Cell type enhanced" "Detected in many" "cDC: 207.2;Esophageal apical cells: 130.6;Esophageal suprabasal cells: 148.9;Hofbauer cells: 543.5;Kupffer cells: 385.4;Macrophages: 199.9;Microglia: 175.3;Neutrophil progenitors: 111.3;Platelets: 425.1;Salivary acinar cells: 378.3" "Cell type enriched" "Detected in many" 5 "central nervous system macrophage: 225.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 16 "classical monocyte: 22.7;intermediate monocyte: 17.9;myeloid DC: 12.7;plasmacytoid DC: 27.5" "Group enriched" "Detected in many" 19 "dendritic cells: 27.5;monocytes: 22.7" "Not detected" "Not detected" "Adipose visceral - T-cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Fibroblasts, Spleen - Macrophages, Thyroid gland - Fibroblasts" HPA023262 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 51: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" "Plasma membrane, Cytosol" "HPA023262: " "unprognostic (1.45e-1)" "unprognostic (4.20e-2)" "unprognostic (2.79e-1)" "unprognostic (1.35e-2)" "unprognostic (3.22e-2)" "unprognostic (2.31e-2)" "unprognostic (1.16e-2)" "unprognostic (1.93e-2)" "unprognostic (1.68e-2)" "unprognostic (7.83e-2)" "unprognostic (6.77e-3)" "unprognostic (1.99e-2)" "unprognostic (4.16e-3)" "unprognostic (1.63e-1)" "unprognostic (1.12e-3)" "unprognostic (1.06e-1)" "unprognostic (1.06e-1)" "unprognostic (1.64e-1)" "unprognostic (8.18e-2)" "unprognostic (7.29e-2)" "unprognostic (1.20e-1)" "unprognostic (2.83e-1)" "unprognostic (1.75e-1)" "unprognostic (5.10e-2)" "unprognostic (2.07e-2)" "unprognostic (1.95e-1)" "unprognostic (3.98e-2)" "unprognostic (3.71e-2)" "unprognostic (8.85e-2)" "unprognostic (1.05e-2)" GGTLC1 "dJ831C21.1, dJ831C21.2, GGTLA3, GGTLA4" ENSG00000149435 "Gamma-glutamyltransferase light chain 1" Q9BX51 20 23985050-23988779 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 12 "lung: 31.2;testis: 17.3" "Group enriched" "Detected in some" 4 "Alveolar cells type 1: 202.5;Late primary spermatocytes: 85.4;Late spermatids: 226.1" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 15 "Lung Adenocarcinoma (TCGA): 30.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Alveolar cells type 1, Testis - Early spermatids, Testis - Late spermatids" "HPA045635, HPA047534" Uncertain NA NA "Cluster 13: Lung - Secretion" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 1 "HPA045635: , HPA047534: " "potential prognostic favorable (1.42e-4)" "unprognostic (5.21e-1)" "unprognostic (4.88e-3)" "unprognostic (9.10e-2)" "unprognostic (3.85e-1)" GGTLC2 GGTL4 ENSG00000100121 "Gamma-glutamyltransferase light chain 2" Q14390 22 22644614-22647898 "Essential proteins, Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 35.1" "Group enriched" "Detected in some" 12 "Early spermatids: 19.6;Late primary spermatocytes: 27.1;Late spermatids: 55.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Thyroid Carcinoma (TCGA): 1.7;Uterine Corpus Endometrial Carcinoma (TCGA): 2.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in some" "HPA045635, HPA047534" Uncertain NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 47: Testis - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 1 "HPA045635: , HPA047534: " "unprognostic (2.50e-1)" "unprognostic (1.35e-2)" "unprognostic (1.43e-1)" "unprognostic (6.06e-3)" GGTLC3 ENSG00000274252 "Gamma-glutamyltransferase light chain family member 3" B5MD39 22 18516344-18518161 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "kidney: 11.5;thyroid gland: 8.2" "Cell type enriched" "Detected in single" 4 "Alveolar cells type 1: 2.9" "Cancer enhanced" "Detected in some" "Thyroid Carcinoma (TCGA): 6.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "testis cancer: 2.1" "HPA045635, HPA047534" Uncertain NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 15: Kidney cancer - Membrane components" "Cluster 81: Alveolar cells - Lung function" "HPA045635: , HPA047534: " "unprognostic (3.91e-3)" "unprognostic (1.44e-3)" "unprognostic (2.52e-1)" "potential prognostic favorable (6.17e-4)" "potential prognostic favorable (9.74e-5)" GH1 "GH, GH-N, GHN, hGH-N" ENSG00000259384 "Growth hormone 1" P01241 17 63917200-63918839 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Hormone "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1024 "pituitary gland: 56119.9" "Cell type enriched" "Detected in some" 111 "Somatotrophs: 379.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pituitary gland - Somatotropes" HPA043715 Supported "Secreted to blood" Hormone NA NA 2690000 3800000 "Cluster 20: Pituitary gland - Hormone signaling" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 3 "HPA043715: " GH2 "GH-V, GHL, GHV, hGH-V" ENSG00000136487 "Growth hormone 2" P01242 17 63880215-63881944 "Cancer-related genes, Predicted secreted proteins" Hormone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 88 "pituitary gland: 94.7;placenta: 120.3" "Group enriched" "Detected in some" 13 "Extravillous trophoblasts: 12.5;Somatotrophs: 13.7;Syncytiotrophoblasts: 20.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "testis cancer: 1.1" "Pituitary gland - Somatotropes" HPA043715 Supported "Secreted to blood" Hormone NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 34: Testis cancer - Unknown function" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." 1 "HPA043715: " GHDC LGP1 ENSG00000167925 "GH3 domain containing" Q8N2G8 17 42188799-42194532 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 42.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031650 Uncertain "Intracellular and membrane" "No annotated function" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 5 "HPA031650: " "unprognostic (3.84e-2)" "unprognostic (1.49e-2)" "unprognostic (2.03e-1)" "unprognostic (3.91e-2)" "unprognostic (1.33e-1)" "unprognostic (1.09e-1)" "potential prognostic unfavorable (1.18e-4)" "unprognostic (2.02e-3)" "unprognostic (1.89e-1)" "unprognostic (3.93e-1)" "potential prognostic favorable (1.62e-11)" "unprognostic (1.72e-3)" "potential prognostic favorable (5.16e-5)" "unprognostic (6.25e-3)" "unprognostic (1.19e-3)" "unprognostic (1.94e-1)" "unprognostic (1.16e-1)" "unprognostic (1.94e-2)" "unprognostic (2.68e-1)" "unprognostic (2.36e-3)" "unprognostic (5.92e-2)" "unprognostic (4.08e-2)" "unprognostic (1.76e-1)" "unprognostic (2.80e-2)" "potential prognostic favorable (2.69e-5)" "unprognostic (1.44e-2)" "unprognostic (2.60e-1)" "unprognostic (1.53e-1)" "unprognostic (1.74e-2)" "unprognostic (7.72e-2)" "unprognostic (2.76e-2)" GHITM "DERP2, HSPC282, My021, PTD010, TMBIM5" ENSG00000165678 "Growth hormone inducible transmembrane protein" Q9H3K2 10 84139482-84154841 "Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 1201.2;Late spermatids: 3986.8;Parietal cells: 1085.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016464, HPA061664" Approved Supported Mitochondria NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 14: Neurons - Synaptic function" "Cluster 52: Non-specific - Mitochondria" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 57 Mitochondria "HPA016464: , HPA061664: " "unprognostic (3.17e-1)" "unprognostic (2.64e-3)" "unprognostic (6.30e-2)" "unprognostic (1.52e-1)" "unprognostic (3.43e-2)" "unprognostic (3.45e-1)" "unprognostic (6.40e-2)" "unprognostic (1.25e-3)" "potential prognostic unfavorable (3.08e-4)" "unprognostic (1.82e-2)" "potential prognostic favorable (2.86e-9)" "unprognostic (2.72e-2)" "unprognostic (5.78e-3)" "unprognostic (1.18e-1)" "unprognostic (2.40e-1)" "unprognostic (2.22e-2)" "unprognostic (4.22e-2)" "unprognostic (1.43e-1)" "unprognostic (7.62e-2)" "unprognostic (3.91e-1)" "unprognostic (3.88e-3)" "unprognostic (3.43e-3)" "unprognostic (5.85e-2)" "unprognostic (2.17e-1)" "unprognostic (8.48e-2)" "unprognostic (1.28e-1)" "unprognostic (2.95e-1)" "unprognostic (4.75e-2)" "unprognostic (1.89e-1)" "unprognostic (2.00e-2)" "unprognostic (4.33e-3)" GHR GHBP ENSG00000112964 "Growth hormone receptor" P10912 5 42423439-42721878 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Endocytosis Receptor "Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 79.5;liver: 199.5" "Group enriched" "Detected in many" 4 "Adipocytes: 3141.2;Myonuclei: 1159.6" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 17.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 6.9" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045339, HPA057705" Enhanced Supported "Plasma membrane,Cytosol,Cytoplasmic bodies" "Secreted to blood" Receptor NA NA 2200000 3600000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 3: Rhabdoid - Membrane components" "Cluster 89: Adipocytes - Lipid metabolism" 31 "Plasma membrane, Cytosol, Cytoplasmic bodies" "HPA045339: , HPA057705: " "unprognostic (6.47e-2)" "unprognostic (1.26e-2)" "unprognostic (8.47e-2)" "unprognostic (1.11e-2)" "unprognostic (3.23e-1)" "unprognostic (4.88e-2)" "unprognostic (2.95e-1)" "potential prognostic favorable (4.80e-5)" "unprognostic (3.73e-2)" "unprognostic (6.78e-2)" "validated prognostic favorable (2.53e-10)" "validated prognostic favorable (1.24e-4)" "unprognostic (2.09e-1)" "validated prognostic favorable (3.06e-6)" "validated prognostic favorable (1.71e-4)" "unprognostic (2.92e-2)" "unprognostic (1.51e-1)" "unprognostic (8.98e-2)" "unprognostic (5.90e-2)" "unprognostic (2.97e-3)" "unprognostic (3.57e-2)" "unprognostic (8.96e-2)" "unprognostic (1.13e-2)" "unprognostic (1.27e-1)" "unprognostic (5.69e-3)" "unprognostic (1.43e-1)" "potential prognostic unfavorable (6.29e-4)" GHRH GHRF ENSG00000118702 "Growth hormone releasing hormone" P01286 20 37251086-37261819 "Human disease related genes, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 64.3" "Cell type enriched" "Detected in some" 4 "Other brain neurons: 11.3" "Cell type enriched" "Detected in single" 5 "splatter: 3.2" "Cancer enriched" "Detected in some" 4 "Bladder Urothelial Carcinoma (TCGA): 25.7" "Region enriched" "Detected in single" 542 "hypothalamus: 428.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 72 "lung cancer: 28.6" "Region enriched" "Detected in many" 9 "hypothalamus: 32.9" "Region enhanced" "Detected in some" "hypothalamus: 4.9" "Secreted in other tissues" "No annotated function" NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 98: Neurons - Neurotransmission & signaling" "unprognostic (2.46e-2)" "unprognostic (3.31e-1)" "unprognostic (1.32e-1)" "unprognostic (3.88e-2)" "unprognostic (2.11e-2)" GHRHR ENSG00000106128 "Growth hormone releasing hormone receptor" Q02643 7 30938669-30993254 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 354 "pituitary gland: 197.2" "Cell type enriched" "Detected in some" 6 "Somatotrophs: 662.9" "Low cell type specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "prostate cancer: 2.1" "Adrenal gland - Adrenal medulla cells, Kidney - Proximal tubular cells, Pituitary gland - Somatotropes, Prostate - Prostate glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 20: Pituitary gland - Hormone signaling" "Cluster 60: Prostate cancer - Unknown function" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" "unprognostic (1.86e-1)" "unprognostic (1.02e-1)" GHRL "ghrelin, MTLRP, obestatin" ENSG00000157017 "Ghrelin and obestatin prepropeptide" Q9UBU3 3 10285666-10292947 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 20 "stomach 1: 356.3" "Cell type enriched" "Detected in many" 13 "Neuroendocrine cells: 12020.2" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 11.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 17.6;classical monocyte: 11.1;eosinophil: 12.4;myeloid DC: 41.9;neutrophil: 25.9;plasmacytoid DC: 28.6" "Group enriched" "Detected in many" 6 "dendritic cells: 41.9;granulocytes: 25.9;monocytes: 11.1" "Low cancer specificity" "Detected in many" "Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA014246, CAB022731" Enhanced "Secreted to blood" Hormone NA NA 2580000 230000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 60: Stomach - Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 4 "CAB022731: , HPA014246: " "unprognostic (1.25e-3)" "unprognostic (5.37e-3)" "unprognostic (6.12e-2)" "unprognostic (2.56e-3)" "unprognostic (1.31e-1)" "unprognostic (2.28e-1)" "unprognostic (2.27e-1)" "unprognostic (7.07e-3)" "potential prognostic favorable (3.74e-5)" "potential prognostic unfavorable (3.12e-4)" "unprognostic (4.13e-2)" "unprognostic (5.09e-1)" "unprognostic (2.74e-2)" "unprognostic (1.32e-1)" "unprognostic (1.78e-2)" "unprognostic (2.64e-1)" "unprognostic (1.97e-1)" "unprognostic (6.56e-2)" "unprognostic (8.39e-2)" "unprognostic (1.09e-1)" "unprognostic (2.73e-2)" "unprognostic (2.21e-1)" "unprognostic (1.67e-1)" "unprognostic (1.10e-1)" "unprognostic (2.22e-1)" "unprognostic (1.16e-1)" "unprognostic (9.37e-2)" "unprognostic (3.42e-3)" "unprognostic (1.93e-1)" GHSR ENSG00000121853 "Growth hormone secretagogue receptor" Q92847 3 172443291-172448456 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "pituitary gland: 3.5" "Cell type enhanced" "Detected in some" "Corticotrophs: 17.5;Gonadotrophs: 2.1;Lactotrophs: 5.8;NK-cells: 1.8;Other brain neurons: 2.2;Pancreatic islet cells: 3.6;Somatotrophs: 19.3;Thyrotrophs: 4.8" "Cell type enhanced" "Detected in some" "hippocampal CA4: 7.2;hippocampal dentate gyrus: 3.5" "Not detected" "Not detected" "Region enriched" "Detected in many" 4 "hypothalamus: 32.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adrenal gland - Adrenal medulla cells, Pituitary gland - Somatotropes" "Region enhanced" "Detected in some" "hypothalamus: 3.3" "Low region specificity" "Detected in all" NA NA "Cluster 20: Pituitary gland - Hormone signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" GID4 "C17orf39, VID24" ENSG00000141034 "GID complex subunit 4 homolog" Q8IVV7 17 18039408-18068405 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 67.5" "Group enriched" "Detected in many" 4 "Early spermatids: 845.7;Late spermatids: 1672.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "testis cancer: 59.7" "Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044348 Uncertain Approved Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 67: Testis - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 42: Non-specific - Unknown function" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 42 Cytosol "HPA044348: " "unprognostic (8.48e-2)" "unprognostic (4.98e-2)" "unprognostic (2.22e-2)" "unprognostic (1.64e-1)" "unprognostic (1.46e-1)" "unprognostic (2.52e-1)" "unprognostic (8.12e-2)" "unprognostic (1.04e-1)" "unprognostic (1.25e-1)" "validated prognostic favorable (6.69e-5)" "validated prognostic favorable (6.59e-4)" "unprognostic (3.11e-1)" "unprognostic (5.88e-2)" "unprognostic (2.25e-1)" "unprognostic (2.60e-1)" "unprognostic (9.50e-2)" "unprognostic (1.83e-1)" "unprognostic (3.54e-1)" "unprognostic (5.14e-3)" "unprognostic (1.01e-1)" "unprognostic (8.25e-2)" "unprognostic (1.08e-1)" "unprognostic (1.19e-2)" "unprognostic (2.52e-1)" "unprognostic (7.73e-2)" "unprognostic (3.45e-1)" "unprognostic (1.76e-1)" "unprognostic (2.03e-1)" "unprognostic (2.16e-1)" GID8 "bA305P22.1, C20orf11, FLJ20602, TWA1" ENSG00000101193 "GID complex subunit 8 homolog" Q9NWU2 20 62938147-62948475 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Esophageal apical cells: 1003.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049929, HPA055047" Approved Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 54: Non-specific - Ribosome" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 62: Non-specific - Plasma proteins" "Cluster 84: Apical squamous epithelium - Cornification" 83 Nucleoplasm "Cell Junctions" "HPA049929: , HPA055047: " "unprognostic (9.47e-2)" "unprognostic (7.07e-2)" "unprognostic (2.28e-1)" "unprognostic (3.84e-1)" "unprognostic (7.08e-2)" "unprognostic (1.34e-1)" "unprognostic (9.78e-2)" "unprognostic (2.22e-1)" "unprognostic (1.60e-1)" "validated prognostic favorable (9.07e-5)" "validated prognostic favorable (4.00e-4)" "unprognostic (1.63e-1)" "unprognostic (1.83e-2)" "unprognostic (1.23e-2)" "unprognostic (5.76e-2)" "unprognostic (1.21e-1)" "unprognostic (1.43e-1)" "unprognostic (6.98e-2)" "unprognostic (2.57e-1)" "unprognostic (1.39e-1)" "unprognostic (1.27e-2)" "unprognostic (1.74e-1)" "unprognostic (8.40e-3)" "unprognostic (5.17e-2)" "unprognostic (2.47e-1)" "unprognostic (2.98e-1)" "unprognostic (1.74e-1)" "unprognostic (3.50e-2)" "unprognostic (7.38e-2)" GIGYF1 "GYF1, PERQ1" ENSG00000146830 "GRB10 interacting GYF protein 1" O75420 7 100679507-100694250 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020999, HPA023995" Enhanced Approved "Vesicles,Microtubules,Mitotic spindle,Primary cilium,Basal body" Yes NA "Cluster 21: Neutrophils - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 39: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 68 Vesicles "Microtubules, Mitotic spindle, Primary cilium, Basal body" "HPA020999: , HPA023995: " "unprognostic (4.28e-3)" "unprognostic (3.73e-3)" "unprognostic (7.00e-2)" "unprognostic (2.92e-2)" "unprognostic (1.92e-2)" "unprognostic (7.25e-2)" "unprognostic (2.59e-1)" "unprognostic (1.92e-2)" "unprognostic (1.15e-3)" "unprognostic (8.18e-2)" "unprognostic (2.68e-2)" "unprognostic (1.37e-2)" "unprognostic (8.12e-3)" "unprognostic (1.39e-3)" "unprognostic (1.82e-1)" "unprognostic (1.79e-2)" "unprognostic (1.89e-1)" "unprognostic (3.14e-2)" "unprognostic (2.59e-2)" "unprognostic (3.03e-3)" "unprognostic (4.15e-2)" "potential prognostic favorable (1.77e-5)" "potential prognostic unfavorable (9.45e-4)" "unprognostic (8.10e-2)" "unprognostic (1.03e-1)" "unprognostic (1.48e-2)" "unprognostic (2.25e-2)" "unprognostic (8.45e-2)" "unprognostic (3.22e-1)" "unprognostic (2.18e-2)" "unprognostic (1.87e-1)" GIGYF2 "GYF2, KIAA0642, PARK11, PERQ2, PERQ3, TNRC15" ENSG00000204120 "GRB10 interacting GYF protein 2" Q6Y7W6 2 232697299-232860605 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 997.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Endothelial cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050899, HPA054612, HPA059918, HPA065064" Approved Enhanced Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 40 Cytosol "HPA050899: , HPA054612: , HPA059918: , HPA065064: " "unprognostic (1.26e-1)" "unprognostic (1.64e-2)" "unprognostic (5.40e-2)" "unprognostic (3.01e-2)" "unprognostic (1.30e-1)" "unprognostic (1.80e-1)" "unprognostic (1.93e-2)" "unprognostic (1.49e-1)" "unprognostic (7.80e-2)" "unprognostic (1.70e-2)" "validated prognostic favorable (1.68e-7)" "validated prognostic favorable (4.95e-4)" "unprognostic (2.17e-1)" "unprognostic (1.33e-2)" "unprognostic (4.30e-2)" "unprognostic (8.50e-2)" "unprognostic (9.63e-2)" "unprognostic (4.52e-2)" "unprognostic (8.89e-2)" "unprognostic (1.69e-2)" "unprognostic (5.11e-2)" "unprognostic (1.62e-2)" "unprognostic (5.72e-3)" "unprognostic (9.48e-2)" "unprognostic (1.57e-1)" "unprognostic (2.33e-3)" "unprognostic (4.80e-2)" "unprognostic (1.03e-1)" "unprognostic (1.28e-1)" "unprognostic (4.22e-2)" "unprognostic (1.42e-1)" GIMAP1 "HIMAP1, IAN2, IMAP1, IMAP38" ENSG00000213203 "GTPase, IMAP family member 1" Q8WWP7 7 150716606-150724284 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 23.3" "Cell type enriched" "Detected in some" 11 "Microglia: 36.5" "Group enriched" "Detected in some" 6 "central nervous system macrophage: 43.5;endothelial cell: 82.1;leukocyte: 50.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in single" 17 "Leukemia: 3.6" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Minor Salivary Gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Spleen - Macrophages, Testis - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA044887, HPA053441" Uncertain Supported "Endoplasmic reticulum" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 59: Leukemia - T-cell receptor" "Cluster 104: Brain endothelial cells - Blood brain barrier" 40 "Endoplasmic reticulum" "HPA044887: , HPA053441: " "unprognostic (2.21e-1)" "unprognostic (4.13e-2)" "unprognostic (4.10e-3)" "unprognostic (1.81e-2)" "unprognostic (4.08e-2)" "unprognostic (2.35e-1)" "unprognostic (2.65e-1)" "unprognostic (2.83e-1)" "potential prognostic favorable (4.80e-4)" "unprognostic (2.33e-1)" "potential prognostic favorable (1.61e-6)" "unprognostic (1.19e-2)" "unprognostic (1.11e-1)" "potential prognostic favorable (9.91e-4)" "unprognostic (3.64e-3)" "potential prognostic favorable (4.31e-4)" "unprognostic (4.40e-2)" "unprognostic (1.08e-1)" "unprognostic (1.71e-1)" "unprognostic (9.65e-2)" "unprognostic (3.35e-1)" "unprognostic (2.11e-2)" "unprognostic (7.59e-2)" "unprognostic (9.67e-2)" "unprognostic (2.15e-1)" "unprognostic (1.93e-1)" "unprognostic (1.33e-1)" "unprognostic (2.92e-2)" "unprognostic (4.02e-3)" "unprognostic (3.41e-1)" "unprognostic (5.53e-2)" GIMAP1-GIMAP5 ENSG00000281887 "GIMAP1-GIMAP5 readthrough" 7 150716668-150743646 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 5.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "monocytes: 38.0;NK-cells: 69.8;T-cells: 101.5" "Cancer enriched" "Detected in single" 11 "Leukemia: 1.0" HPA053441 Supported "Endoplasmic reticulum" NA NA "Cluster 27: T-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 59: Leukemia - T-cell receptor" "Endoplasmic reticulum" "HPA053441: " "unprognostic (1.36e-1)" "unprognostic (1.83e-1)" "unprognostic (1.12e-1)" "unprognostic (2.51e-1)" "unprognostic (8.70e-2)" "potential prognostic favorable (4.19e-5)" "unprognostic (7.44e-2)" "unprognostic (6.33e-3)" "unprognostic (2.57e-2)" "unprognostic (1.15e-1)" "unprognostic (5.47e-2)" "unprognostic (2.23e-2)" "unprognostic (2.94e-1)" GIMAP2 "DKFZp586D0824, HIMAP2, IAN12, IMAP2" ENSG00000106560 "GTPase, IMAP family member 2" Q9UG22 7 150685697-150693641 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 73.4" "Cell type enhanced" "Detected in many" "Hematopoietic stem cells: 56.3;Hofbauer cells: 47.2;Innate lymphoid cells: 31.7;Kupffer cells: 202.9;Macrophages: 35.2;Microglia: 27.6;monocytes: 58.5;Neutrophils: 31.9;NK-cells: 39.5;T-cells: 48.5;Thymocytes: 48.3;Vascular endothelial cells: 31.5" "Group enriched" "Detected in some" 6 "central nervous system macrophage: 34.2;endothelial cell: 21.4;leukocyte: 43.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 34.3" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in some" "HPA013589, HPA014746" Approved Supported "Nucleoplasm,Lipid droplets" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 4 "Lipid droplets" Nucleoplasm "HPA013589: , HPA014746: " "potential prognostic favorable (3.99e-5)" "potential prognostic favorable (8.01e-4)" "unprognostic (3.98e-2)" "unprognostic (1.35e-1)" "unprognostic (1.23e-1)" "unprognostic (1.98e-1)" "unprognostic (3.25e-2)" "unprognostic (1.49e-2)" "unprognostic (7.69e-3)" "unprognostic (2.83e-1)" "potential prognostic favorable (4.45e-5)" "unprognostic (1.12e-2)" "unprognostic (1.47e-2)" "unprognostic (1.39e-2)" "unprognostic (1.21e-1)" "unprognostic (3.66e-3)" "unprognostic (1.22e-1)" "unprognostic (4.04e-2)" "unprognostic (4.18e-1)" "unprognostic (2.63e-1)" "unprognostic (2.42e-2)" "unprognostic (4.17e-2)" "unprognostic (2.89e-2)" "unprognostic (8.13e-2)" "unprognostic (7.24e-3)" "unprognostic (1.38e-1)" "unprognostic (8.85e-3)" "unprognostic (2.33e-1)" "unprognostic (2.87e-2)" "unprognostic (5.25e-2)" "unprognostic (2.13e-1)" GIMAP4 "FLJ11110, HIMAP4, IAN1, IMAP4" ENSG00000133574 "GTPase, IMAP family member 4" Q9NUV9 7 150567369-150573953 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 119.6" "Cell type enhanced" "Detected in some" "cDC: 42.8;Hofbauer cells: 143.1;Kupffer cells: 276.7;Lymphatic endothelial cells: 173.9;Macrophages: 92.2;Microglia: 62.3;monocytes: 112.3;Neutrophils: 113.2;NK-cells: 104.0;T-cells: 128.1;Vascular endothelial cells: 202.3" "Group enriched" "Detected in some" 11 "central nervous system macrophage: 70.2;endothelial cell: 71.7;leukocyte: 74.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Leukemia: 4.3;pancreatic cancer: 9.7" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Minor Salivary Gland - Endothelial cells, Pituitary gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Spleen - Macrophages, Testis - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA019135, HPA019137, HPA027198" Enhanced Approved Vesicles,Cytosol NA NA 5000 "Cluster 33: Non-specific - ATP binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 1 "Vesicles, Cytosol" "HPA019135: , HPA019137: , HPA027198: " "unprognostic (4.67e-2)" "unprognostic (7.56e-2)" "unprognostic (3.09e-1)" "potential prognostic favorable (6.16e-4)" "unprognostic (3.65e-2)" "unprognostic (1.54e-1)" "unprognostic (1.63e-1)" "unprognostic (1.59e-1)" "unprognostic (1.58e-2)" "unprognostic (2.16e-1)" "potential prognostic favorable (3.12e-6)" "unprognostic (1.51e-2)" "unprognostic (5.35e-2)" "unprognostic (5.21e-2)" "unprognostic (1.79e-2)" "potential prognostic favorable (2.09e-4)" "unprognostic (1.63e-1)" "unprognostic (1.14e-1)" "unprognostic (2.48e-1)" "unprognostic (1.85e-1)" "unprognostic (4.14e-1)" "unprognostic (1.66e-1)" "unprognostic (2.62e-1)" "unprognostic (4.82e-2)" "unprognostic (3.57e-1)" "unprognostic (3.50e-1)" "unprognostic (6.50e-2)" "unprognostic (3.64e-2)" "unprognostic (2.32e-2)" "unprognostic (8.17e-2)" "unprognostic (1.76e-1)" GIMAP5 "HIMAP3, IAN4L1, IAN5" ENSG00000196329 "GTPase, IMAP family member 5" Q96F15 7 150722253-150750033 "Disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 99.5" "Cell type enhanced" "Detected in some" "Hofbauer cells: 4.1;Innate lymphoid cells: 3.1;Kupffer cells: 7.2;Lymphatic endothelial cells: 4.8;Macrophages: 4.2;Microglia: 21.4;monocytes: 3.4;NK-cells: 7.4;T-cells: 8.1;Vascular endothelial cells: 10.7" "Group enriched" "Detected in some" 7 "central nervous system macrophage: 29.6;endothelial cell: 108.9;leukocyte: 64.7" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 47.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in some" 7 "Leukemia: 9.9" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Minor Salivary Gland - Endothelial cells, Pituitary gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 59: Leukemia - T-cell receptor" "Cluster 104: Brain endothelial cells - Blood brain barrier" 54 "unprognostic (9.07e-2)" "unprognostic (8.99e-2)" "unprognostic (6.90e-3)" "unprognostic (1.57e-2)" "unprognostic (5.45e-2)" "unprognostic (1.54e-1)" "unprognostic (9.64e-2)" "unprognostic (2.08e-3)" "unprognostic (5.21e-3)" "unprognostic (7.78e-2)" "potential prognostic favorable (1.89e-8)" "unprognostic (1.94e-3)" "unprognostic (2.47e-2)" "unprognostic (1.37e-3)" "unprognostic (3.57e-2)" "potential prognostic favorable (8.07e-4)" "unprognostic (1.49e-1)" "unprognostic (1.19e-1)" "unprognostic (1.34e-1)" "unprognostic (1.03e-1)" "unprognostic (7.13e-2)" "unprognostic (5.61e-2)" "unprognostic (2.51e-1)" "unprognostic (1.10e-1)" "unprognostic (8.29e-2)" "unprognostic (8.65e-2)" "unprognostic (2.14e-1)" "unprognostic (4.77e-1)" "unprognostic (5.05e-2)" "unprognostic (1.90e-1)" "unprognostic (1.55e-1)" GIMAP6 "FLJ22690, IAN6" ENSG00000133561 "GTPase, IMAP family member 6" Q6P9H5 7 150625375-150632648 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 60.3" "Cell type enhanced" "Detected in some" "Hofbauer cells: 59.6;Innate lymphoid cells: 34.6;Kupffer cells: 120.9;Lymphatic endothelial cells: 57.4;Macrophages: 21.5;monocytes: 26.4;NK-cells: 43.3;T-cells: 30.7;Vascular endothelial cells: 87.0" "Group enriched" "Detected in some" 13 "central nervous system macrophage: 14.8;endothelial cell: 49.5;leukocyte: 28.6" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 34.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "monocytes: 75.2;NK-cells: 217.7;T-cells: 127.4" "Cancer enriched" "Detected in some" 6 "Leukemia: 17.5" "Heart muscle - Endothelial cells, Kidney - Endothelial cells, Prostate - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026715, HPA050740" Approved NA NA "Cluster 1: T-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 59: Leukemia - T-cell receptor" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "HPA026715: , HPA050740: " "unprognostic (9.90e-2)" "unprognostic (1.42e-1)" "unprognostic (8.29e-2)" "unprognostic (4.58e-2)" "unprognostic (2.92e-2)" "unprognostic (1.50e-1)" "unprognostic (2.46e-1)" "unprognostic (2.44e-1)" "potential prognostic favorable (6.37e-4)" "unprognostic (2.08e-1)" "validated prognostic favorable (1.02e-8)" "validated prognostic favorable (9.43e-4)" "unprognostic (9.82e-3)" "unprognostic (1.10e-3)" "unprognostic (1.62e-2)" "potential prognostic favorable (6.74e-5)" "unprognostic (3.76e-1)" "unprognostic (1.70e-1)" "unprognostic (2.41e-1)" "unprognostic (3.89e-2)" "unprognostic (2.16e-1)" "unprognostic (8.94e-2)" "unprognostic (2.46e-1)" "unprognostic (2.35e-1)" "unprognostic (4.32e-1)" "unprognostic (3.47e-2)" "unprognostic (1.90e-1)" "unprognostic (2.22e-1)" "unprognostic (3.24e-2)" "unprognostic (2.48e-1)" "unprognostic (1.07e-1)" GIMAP7 "IAN7, MGC27027" ENSG00000179144 "GTPase, IMAP family member 7" Q8NHV1 7 150514872-150521073 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 159.3" "Cell type enhanced" "Detected in some" "Kupffer cells: 137.3;Lymphatic endothelial cells: 234.6;Macrophages: 58.5;Monocyte progenitors: 41.9;monocytes: 67.1;NK-cells: 199.9;T-cells: 187.0;Vascular endothelial cells: 268.4" "Group enriched" "Detected in some" 6 "endothelial cell: 225.8;leukocyte: 169.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "monocytes: 669.9;NK-cells: 1124.1;T-cells: 2276.2" "Cancer enriched" "Detected in single" 19 "Leukemia: 18.0" "Colon - Endothelial cells, Heart muscle - Endothelial cells, Minor Salivary Gland - Endothelial cells, Skeletal muscle - Endothelial cells, Testis - Endothelial cells" "Not detected" "Not detected" "HPA020266, HPA020268" Enhanced Supported "Golgi apparatus,Vesicles" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 59: Leukemia - T-cell receptor" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "Golgi apparatus, Vesicles" "HPA020266: , HPA020268: " "unprognostic (7.74e-3)" "unprognostic (4.72e-3)" "unprognostic (5.71e-3)" "unprognostic (6.19e-3)" "unprognostic (1.95e-2)" "unprognostic (1.82e-1)" "unprognostic (1.66e-1)" "unprognostic (9.06e-2)" "potential prognostic favorable (6.41e-4)" "unprognostic (2.77e-1)" "potential prognostic favorable (2.72e-7)" "unprognostic (1.01e-3)" "unprognostic (1.29e-2)" "potential prognostic favorable (7.21e-4)" "unprognostic (2.58e-3)" "potential prognostic favorable (8.82e-6)" "unprognostic (1.28e-1)" "unprognostic (2.22e-1)" "unprognostic (2.34e-1)" "unprognostic (1.08e-2)" "unprognostic (1.54e-1)" "unprognostic (1.38e-2)" "unprognostic (4.76e-2)" "unprognostic (4.34e-1)" "unprognostic (1.77e-1)" "unprognostic (3.74e-2)" "unprognostic (2.23e-1)" "unprognostic (1.52e-1)" "unprognostic (2.35e-2)" "unprognostic (3.43e-1)" "unprognostic (1.06e-1)" GIMAP8 "DKFZp667I133, hIAN6, IAN9" ENSG00000171115 "GTPase, IMAP family member 8" Q8ND71 7 150450630-150479393 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 38.2" "Group enriched" "Detected in some" 4 "Kupffer cells: 145.5;Lymphatic endothelial cells: 112.2;Macrophages: 50.3;Microglia: 88.1;monocytes: 45.6;Vascular endothelial cells: 111.3" "Group enriched" "Detected in some" 14 "central nervous system macrophage: 118.1;endothelial cell: 127.2;leukocyte: 37.6" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 20.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 6 "Leukemia: 1.7;lymphoma: 1.8;Myeloma: 1.2" "Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Minor Salivary Gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA014474, HPA017765" Supported NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "HPA014474: , HPA017765: " "unprognostic (2.97e-2)" "unprognostic (6.98e-2)" "unprognostic (4.19e-2)" "unprognostic (5.91e-2)" "unprognostic (1.32e-1)" "unprognostic (4.38e-2)" "unprognostic (2.20e-1)" "unprognostic (4.13e-1)" "unprognostic (6.16e-3)" "unprognostic (1.03e-1)" "potential prognostic favorable (8.89e-9)" "unprognostic (1.00e-3)" "unprognostic (4.36e-2)" "unprognostic (1.91e-3)" "unprognostic (5.21e-3)" "potential prognostic favorable (1.41e-4)" "unprognostic (2.77e-1)" "unprognostic (7.13e-2)" "unprognostic (1.18e-1)" "unprognostic (7.24e-2)" "unprognostic (2.67e-1)" "unprognostic (4.14e-2)" "unprognostic (2.93e-1)" "unprognostic (6.51e-2)" "unprognostic (3.00e-1)" "unprognostic (7.86e-2)" "unprognostic (2.99e-2)" "unprognostic (1.47e-1)" "unprognostic (1.18e-2)" "unprognostic (2.89e-1)" "unprognostic (2.03e-1)" GIMD1 ENSG00000250298 "GIMAP family P-loop NTPase domain containing 1" P0DJR0 4 106357392-106368778 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "intestine: 25.8" "Cell type enhanced" "Detected in single" "Thymocytes: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 1: Neuronal - Visual perception" "Cluster 61: Schwann cells & Melanocytes - Mixed function" GIN1 "FLJ20125, GIN-1, TGIN1, ZH2C2" ENSG00000145723 "Gypsy retrotransposon integrase 1" Q9NXP7 5 103086000-103120138 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Myonuclei: 42.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037402, HPA061362" Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 7: Non-specific - Transcription" 2 "Nucleoplasm, Nucleoli" "HPA037402: , HPA061362: " "unprognostic (4.15e-2)" "unprognostic (3.47e-3)" "unprognostic (9.33e-2)" "unprognostic (2.25e-1)" "unprognostic (1.83e-1)" "unprognostic (1.28e-1)" "unprognostic (1.51e-1)" "unprognostic (4.40e-2)" "unprognostic (2.38e-1)" "unprognostic (3.52e-2)" "validated prognostic favorable (7.02e-10)" "validated prognostic favorable (1.70e-4)" "unprognostic (7.97e-2)" "unprognostic (8.77e-2)" "unprognostic (7.00e-2)" "unprognostic (3.30e-1)" "unprognostic (5.24e-1)" "unprognostic (1.88e-1)" "unprognostic (2.65e-1)" "unprognostic (8.39e-2)" "potential prognostic unfavorable (5.15e-6)" "unprognostic (1.54e-1)" "potential prognostic unfavorable (1.32e-5)" "unprognostic (3.94e-1)" "unprognostic (1.31e-2)" "unprognostic (5.55e-2)" "unprognostic (1.94e-1)" "unprognostic (6.25e-2)" "unprognostic (3.35e-1)" "unprognostic (6.58e-2)" "unprognostic (7.00e-2)" GINM1 "C6orf72, dJ12G14.2" ENSG00000055211 "Glycosylated integral membrane protein 1" Q9NU53 6 149566294-149591748 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 698.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017210, HPA041679" Approved Approved "Nucleoli fibrillar center,Plasma membrane" NA NA 89000 "Cluster 20: Non-specific - DNA binding" "Cluster 72: Kidney - Transmembrane transport" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 28: Non-specific - Nuclear processes" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 2 "Nucleoli fibrillar center, Plasma membrane" "HPA017210: , HPA041679: " "unprognostic (5.43e-2)" "unprognostic (6.43e-3)" "unprognostic (1.21e-3)" "unprognostic (4.35e-1)" "unprognostic (3.43e-2)" "unprognostic (1.51e-1)" "unprognostic (7.03e-2)" "unprognostic (2.39e-3)" "unprognostic (6.21e-2)" "potential prognostic favorable (2.49e-6)" "unprognostic (1.67e-1)" "unprognostic (6.37e-2)" "unprognostic (1.17e-2)" "unprognostic (2.22e-1)" "unprognostic (2.40e-1)" "unprognostic (1.54e-1)" "unprognostic (5.06e-2)" "unprognostic (2.24e-1)" "unprognostic (1.92e-2)" "unprognostic (3.20e-1)" "unprognostic (1.36e-1)" "unprognostic (1.38e-1)" "unprognostic (3.58e-1)" "unprognostic (5.41e-3)" "unprognostic (6.66e-2)" "unprognostic (3.76e-3)" "unprognostic (1.65e-1)" "unprognostic (1.29e-1)" "unprognostic (2.91e-1)" GINS1 "KIAA0186, PSF1" ENSG00000101003 "GINS complex subunit 1" Q14691 20 25391008-25452700 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "DNA replication" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 6.8;testis: 8.3" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 52.3;Early primary spermatocytes: 66.1;Early spermatids: 100.6;Erythrocyte progenitors: 55.9;Late primary spermatocytes: 74.0;Megakaryocyte progenitors: 48.8;Monocyte progenitors: 47.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051185 Uncertain Approved Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 62: Non-specific - Plasma proteins" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" 19 Nucleoplasm "HPA051185: " "unprognostic (1.98e-1)" "unprognostic (6.59e-3)" "unprognostic (5.22e-2)" "unprognostic (8.88e-3)" "unprognostic (1.62e-2)" "unprognostic (5.65e-2)" "unprognostic (5.45e-1)" "unprognostic (4.32e-2)" "unprognostic (1.08e-1)" "potential prognostic unfavorable (7.31e-4)" "unprognostic (1.55e-3)" "unprognostic (1.09e-3)" "unprognostic (1.98e-3)" "validated prognostic unfavorable (3.07e-7)" "validated prognostic unfavorable (3.44e-7)" "potential prognostic unfavorable (5.59e-4)" "unprognostic (1.61e-3)" "unprognostic (4.17e-2)" "unprognostic (2.32e-1)" "unprognostic (1.63e-2)" "unprognostic (2.16e-1)" "potential prognostic unfavorable (3.88e-6)" "unprognostic (5.54e-3)" "unprognostic (1.58e-1)" "unprognostic (5.34e-2)" "unprognostic (8.82e-2)" "potential prognostic unfavorable (5.30e-4)" "unprognostic (1.65e-1)" "unprognostic (2.89e-1)" "unprognostic (2.19e-1)" "unprognostic (1.76e-2)" GINS2 "Pfs2, PSF2" ENSG00000131153 "GINS complex subunit 2" Q9Y248 16 85676198-85690073 "Essential proteins, Predicted intracellular proteins" "DNA replication" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 13.8" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 118.0;Early primary spermatocytes: 246.7;Enteric stem cells: 55.3;Erythrocyte progenitors: 72.9;Esophageal basal cells: 66.1;Migrating cytotrophoblasts: 60.6;Oocytes: 423.7;Syncytiotrophoblasts: 71.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 8.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Kidney - Fibroblasts, Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA057285 Uncertain Approved Nucleoplasm No Yes "Cluster 9: T-regs - Cell cycle regulation" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 29: Forebrain - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 41: Oocytes - Oogenesis" 25 Nucleoplasm "HPA057285: " "unprognostic (1.16e-1)" "unprognostic (4.50e-2)" "unprognostic (7.96e-2)" "unprognostic (6.05e-3)" "unprognostic (1.93e-1)" "unprognostic (3.30e-1)" "unprognostic (2.03e-1)" "unprognostic (5.56e-2)" "unprognostic (6.11e-2)" "unprognostic (1.38e-1)" "unprognostic (1.86e-2)" "unprognostic (4.61e-3)" "unprognostic (2.66e-2)" "validated prognostic unfavorable (7.63e-4)" "validated prognostic unfavorable (1.09e-6)" "validated prognostic unfavorable (8.97e-4)" "validated prognostic unfavorable (2.60e-4)" "unprognostic (3.68e-2)" "unprognostic (4.27e-2)" "unprognostic (9.81e-2)" "unprognostic (1.51e-1)" "unprognostic (1.84e-2)" "unprognostic (3.04e-3)" "unprognostic (1.11e-2)" "unprognostic (1.06e-1)" "unprognostic (8.89e-2)" "unprognostic (1.81e-2)" "unprognostic (4.41e-2)" "unprognostic (1.31e-1)" "unprognostic (5.69e-3)" "unprognostic (9.85e-2)" GINS3 "FLJ13912, PSF3" ENSG00000181938 "GINS complex subunit 3" Q9BRX5 16 58295080-58406147 "Essential proteins, Predicted intracellular proteins" "DNA replication" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 232.7;Cardiomyocytes: 65.7;Early spermatids: 117.5;Ependymal cells: 68.8;Late primary spermatocytes: 99.8;Oligodendrocyte progenitor cells: 75.8;Oligodendrocytes: 40.6;Schwann cells: 84.5" "Cell type enhanced" "Detected in all" "astrocyte: 307.9;committed oligodendrocyte precursor: 207.2;oligodendrocyte precursor cell: 111.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Colon - Enteric glia cells, Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041216, HPA048209" Uncertain Enhanced Nucleoplasm No No "Cluster 13: Non-specific - Mitochondria" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 54: Immune cells - T cell receptor" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 28: Astrocytes - Homeostasis & neuron support" 25 Nucleoplasm "HPA041216: , HPA048209: " "unprognostic (3.73e-2)" "unprognostic (2.32e-1)" "unprognostic (2.53e-1)" "unprognostic (1.97e-1)" "unprognostic (6.17e-2)" "unprognostic (3.62e-2)" "unprognostic (2.07e-1)" "unprognostic (1.63e-3)" "unprognostic (2.31e-1)" "unprognostic (4.13e-3)" "unprognostic (2.61e-3)" "unprognostic (6.41e-2)" "unprognostic (1.25e-1)" "validated prognostic unfavorable (1.75e-4)" "validated prognostic unfavorable (2.68e-4)" "unprognostic (6.15e-3)" "potential prognostic unfavorable (1.30e-5)" "unprognostic (3.08e-2)" "unprognostic (2.33e-2)" "unprognostic (2.21e-1)" "unprognostic (3.99e-1)" "unprognostic (2.48e-3)" "unprognostic (6.99e-2)" "unprognostic (2.73e-2)" "unprognostic (3.54e-2)" "unprognostic (1.36e-1)" "unprognostic (2.58e-3)" "unprognostic (2.23e-2)" "unprognostic (6.39e-2)" "unprognostic (4.19e-1)" "unprognostic (1.68e-1)" GINS4 "MGC14799, SLD5" ENSG00000147536 "GINS complex subunit 4" Q9BRT9 8 41529218-41545030 "Essential proteins, Predicted intracellular proteins" "DNA replication" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 5.4;lymphoid tissue: 5.7" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 25.9;Extravillous trophoblasts: 15.7;Megakaryocyte progenitors: 28.2;Monocyte progenitors: 26.2;Neutrophils: 35.9" "Cell type enhanced" "Detected in some" "oligodendrocyte: 3.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024663, HPA026580, HPA061075" Uncertain Approved Nucleoplasm,Centrosome NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 11: White matter - Signal transduction" "Cluster 40: Non-specific - Unknown function" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 30 Nucleoplasm Centrosome "HPA024663: , HPA026580: , HPA061075: " "unprognostic (6.10e-2)" "unprognostic (1.07e-1)" "unprognostic (2.79e-1)" "unprognostic (2.08e-1)" "unprognostic (1.63e-2)" "unprognostic (2.99e-1)" "unprognostic (9.64e-2)" "unprognostic (1.80e-1)" "unprognostic (6.19e-3)" "unprognostic (4.49e-3)" "unprognostic (1.22e-2)" "unprognostic (2.44e-3)" "unprognostic (9.77e-3)" "potential prognostic unfavorable (8.65e-4)" "unprognostic (6.94e-3)" "unprognostic (1.41e-3)" "unprognostic (3.01e-3)" "unprognostic (1.71e-2)" "potential prognostic favorable (3.41e-4)" "unprognostic (1.43e-2)" "unprognostic (6.01e-2)" "unprognostic (1.74e-3)" "unprognostic (4.34e-2)" "unprognostic (1.97e-1)" "unprognostic (6.40e-3)" "unprognostic (4.30e-2)" "unprognostic (7.87e-3)" "potential prognostic favorable (8.54e-4)" "unprognostic (7.69e-2)" "unprognostic (8.40e-2)" "unprognostic (6.79e-2)" GIP ENSG00000159224 "Gastric inhibitory polypeptide" P09681 17 48958554-48968596 "FDA approved drug targets, Plasma proteins, Predicted secreted proteins" Hormone "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 209 "intestine: 243.9" "Cell type enriched" "Detected in some" 80 "Neuroendocrine cells: 125.8" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 53 "Testicular Germ Cell Tumor (TCGA): 116.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "liver cancer: 2.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA021612, HPA064596" Enhanced "Secreted to blood" Hormone NA NA 33900 290000 "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 1: Neuronal - Visual perception" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" 15 "HPA021612: , HPA064596: " "unprognostic (5.62e-3)" "unprognostic (2.42e-1)" GIPC1 "C19orf3, GIPC, GLUT1CBP, Hs.6454, NIP, RGS19IP1, SEMCAP, SYNECTIN, TIP-2" ENSG00000123159 "GIPC PDZ domain containing family member 1" O14908 19 14477760-14496149 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Congenital muscular dystrophy, Dystroglycanopathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 338.2" "Cell type enhanced" "Detected in many" "Breast lactating cells: 359.1;Colonocytes: 463.4;Esophageal apical cells: 1928.8;Esophageal suprabasal cells: 624.5;Suprabasal keratinocytes: 305.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043958, HPA061786" Approved Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA 9300 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 18: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 50 "Plasma membrane, Cell Junctions" Nucleoplasm "HPA043958: , HPA061786: " "unprognostic (9.40e-2)" "unprognostic (2.95e-1)" "unprognostic (1.46e-1)" "unprognostic (1.34e-1)" "unprognostic (2.27e-1)" "unprognostic (2.31e-1)" "unprognostic (1.84e-1)" "unprognostic (2.26e-1)" "unprognostic (3.20e-1)" "unprognostic (1.78e-1)" "unprognostic (6.56e-3)" "unprognostic (1.40e-2)" "unprognostic (1.21e-1)" "unprognostic (2.10e-2)" "unprognostic (2.12e-2)" "unprognostic (1.64e-1)" "unprognostic (1.44e-1)" "unprognostic (6.17e-2)" "unprognostic (2.74e-1)" "unprognostic (1.45e-1)" "unprognostic (6.26e-2)" "unprognostic (3.15e-2)" "unprognostic (3.86e-1)" "unprognostic (1.96e-1)" "unprognostic (7.38e-2)" "unprognostic (3.39e-1)" "unprognostic (1.44e-1)" "unprognostic (6.05e-2)" "unprognostic (3.62e-2)" "unprognostic (3.48e-1)" "unprognostic (5.00e-2)" GIPC2 "FLJ20075, SEMCAP-2" ENSG00000137960 "GIPC PDZ domain containing family member 2" Q8TF65 1 77979542-78138444 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 35.8;kidney: 38.7;lymphoid tissue: 26.3" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 303.3;Enterocytes: 227.6;Epididymal efferent duct absorptive cells: 157.1;Pancreatic acinar cells: 140.4;Proximal tubule cells: 201.7" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 17.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Bile duct cancer: 6.6;colorectal cancer: 8.4;Gastric cancer: 6.4;liver cancer: 4.0;pancreatic cancer: 2.5" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Spleen - Endothelial cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA051212, HPA062684" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 8 Nucleoplasm Cytosol "HPA051212: , HPA062684: " "unprognostic (2.16e-1)" "unprognostic (1.02e-2)" "unprognostic (1.85e-2)" "potential prognostic favorable (6.44e-7)" "unprognostic (6.15e-2)" "unprognostic (2.41e-2)" "unprognostic (1.25e-2)" "validated prognostic favorable (1.58e-14)" "validated prognostic favorable (3.26e-7)" "unprognostic (1.78e-2)" "unprognostic (3.73e-1)" "unprognostic (5.89e-2)" "unprognostic (9.39e-2)" "unprognostic (5.46e-2)" "unprognostic (6.30e-2)" "unprognostic (2.84e-2)" "unprognostic (5.36e-2)" "unprognostic (4.48e-2)" "unprognostic (1.75e-1)" "unprognostic (7.94e-2)" "unprognostic (1.69e-1)" "unprognostic (4.08e-2)" GIPC3 "C19orf64, DFNB15, DFNB72, DFNB95" ENSG00000179855 "GIPC PDZ domain containing family member 3" Q8TF64 19 3585478-3593541 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 15.5" "Group enriched" "Detected in some" 4 "Hematopoietic stem cells: 6.3;Hepatic stellate cells: 12.9;Megakaryocyte progenitors: 18.0;Megakaryocytes: 24.7;Platelets: 19.7;Rod photoreceptor cells: 9.1;Vascular endothelial cells: 6.8" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 2.0;endothelial cell: 6.9;pericyte: 3.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 3.4;skin cancer: 3.5" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Liver - Vascular endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA067765 Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus" NA NA "Cluster 42: Retina - Visual perception" "Cluster 47: Endothelial cells - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 1 Nucleoplasm "Nuclear bodies, Golgi apparatus" "HPA067765: " "unprognostic (1.03e-1)" "unprognostic (1.02e-1)" "unprognostic (2.83e-1)" "unprognostic (9.71e-2)" "unprognostic (1.58e-1)" "unprognostic (4.27e-2)" "unprognostic (3.77e-2)" "validated prognostic favorable (5.48e-5)" "validated prognostic favorable (1.48e-6)" "unprognostic (8.86e-2)" "potential prognostic favorable (2.50e-4)" "unprognostic (1.72e-2)" "unprognostic (4.93e-3)" "unprognostic (1.12e-2)" "unprognostic (2.55e-2)" "unprognostic (3.39e-3)" "unprognostic (4.06e-2)" "unprognostic (1.68e-2)" "unprognostic (9.31e-2)" "unprognostic (2.43e-1)" "unprognostic (1.44e-1)" "unprognostic (1.42e-2)" "unprognostic (4.70e-1)" "unprognostic (1.09e-1)" "unprognostic (1.74e-2)" GIPR ENSG00000010310 "Gastric inhibitory polypeptide receptor" P48546 19 45668221-45683722 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 21.4" "Cell type enhanced" "Detected in many" "Colonocytes: 50.4;Epididymal efferent duct ciliated cells: 34.0;Fallopian tube ciliated cells: 40.9;Foveolar cells: 94.6;Goblet cells: 33.1;Neuroendocrine cells: 82.0;Pancreatic islet cells: 54.0;Respiratory ciliated cells: 120.1" "Cell type enhanced" "Detected in some" "ependymal cell: 17.3;oligodendrocyte: 15.5" "Cancer enhanced" "Detected in many" "Pancreatic Adenocarcinoma (TCGA): 12.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB022710, HPA068054" Uncertain Uncertain Vesicles NA NA "Cluster 60: Stomach - Digestion" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" 3 Vesicles "CAB022710: , HPA068054: " "unprognostic (3.89e-2)" "unprognostic (3.71e-2)" "potential prognostic favorable (5.15e-4)" "unprognostic (1.60e-1)" "unprognostic (1.34e-1)" "unprognostic (1.03e-1)" "unprognostic (1.20e-2)" "unprognostic (4.99e-3)" "potential prognostic unfavorable (3.49e-6)" "unprognostic (6.98e-2)" "unprognostic (3.11e-3)" "unprognostic (3.49e-1)" "unprognostic (3.47e-2)" "unprognostic (3.34e-1)" "unprognostic (2.76e-1)" "unprognostic (9.18e-2)" "unprognostic (4.80e-3)" "unprognostic (6.74e-2)" "unprognostic (2.53e-1)" "unprognostic (5.75e-3)" "unprognostic (2.18e-1)" "unprognostic (1.51e-1)" "unprognostic (2.51e-1)" "unprognostic (1.29e-1)" "unprognostic (1.59e-1)" "unprognostic (6.91e-3)" GIT1 ENSG00000108262 "GIT ArfGAP 1" Q9Y2X7 17 29573475-29594054 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 127.9" "Cell type enhanced" "Detected in many" "Early spermatids: 98.2;Late primary spermatocytes: 99.3;Late spermatids: 134.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Lung - Endothelial cells, Minor Salivary Gland - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004059, HPA004186" Enhanced Supported "Focal adhesion sites,Mitochondria,Cytosol" NA NA 27000 "Cluster 33: Non-specific - ATP binding" "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 80 "Focal adhesion sites, Cytosol" Mitochondria "HPA004059: , HPA004186: " "unprognostic (1.63e-1)" "unprognostic (1.26e-1)" "unprognostic (1.59e-1)" "unprognostic (2.86e-1)" "unprognostic (3.40e-2)" "unprognostic (1.68e-1)" "unprognostic (2.22e-1)" "unprognostic (3.95e-3)" "unprognostic (6.27e-2)" "unprognostic (4.66e-2)" "potential prognostic favorable (2.04e-5)" "unprognostic (1.48e-2)" "unprognostic (2.67e-1)" "potential prognostic unfavorable (7.26e-5)" "unprognostic (4.97e-3)" "unprognostic (5.90e-3)" "unprognostic (5.40e-2)" "unprognostic (2.51e-1)" "unprognostic (1.67e-3)" "unprognostic (2.71e-2)" "unprognostic (1.36e-1)" "unprognostic (2.97e-2)" "unprognostic (1.67e-2)" "unprognostic (8.80e-2)" "unprognostic (4.20e-3)" "unprognostic (3.30e-3)" "unprognostic (3.34e-1)" "unprognostic (4.33e-2)" "unprognostic (2.26e-1)" "unprognostic (1.93e-2)" "unprognostic (4.48e-2)" GIT2 "KIAA0148, PKL" ENSG00000139436 "GIT ArfGAP 2" Q14161 12 109929804-109996389 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 381.7;Neutrophils: 619.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB004681 Approved Approved Microtubules NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 61: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 36 Microtubules "CAB004681: " "unprognostic (1.08e-1)" "unprognostic (7.92e-2)" "unprognostic (2.73e-3)" "unprognostic (1.56e-1)" "unprognostic (2.34e-1)" "potential prognostic unfavorable (4.52e-4)" "unprognostic (3.86e-1)" "unprognostic (8.92e-2)" "unprognostic (2.10e-2)" "unprognostic (8.85e-3)" "potential prognostic favorable (1.20e-5)" "unprognostic (1.59e-2)" "unprognostic (1.53e-1)" "unprognostic (2.36e-2)" "unprognostic (2.64e-1)" "unprognostic (1.26e-1)" "unprognostic (1.21e-2)" "unprognostic (1.75e-1)" "unprognostic (5.28e-1)" "unprognostic (2.39e-2)" "unprognostic (1.02e-2)" "unprognostic (2.96e-1)" "unprognostic (1.86e-3)" "unprognostic (1.28e-1)" "unprognostic (1.90e-1)" "unprognostic (5.02e-2)" "unprognostic (2.93e-1)" "unprognostic (6.32e-2)" "unprognostic (1.62e-1)" "unprognostic (8.80e-2)" "unprognostic (1.07e-2)" GJA1 "CX43, GJAL, ODD, ODDD, ODOD, SDTY3" ENSG00000152661 "Gap junction protein alpha 1" P17302 6 121435595-121449727 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cancer-related genes, Cataract, Disease variant, Hypotrichosis, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 446.7;Astrocytes: 470.8;Basal keratinocytes: 182.5;Basal prostatic cells: 192.1;Bergmann glia: 217.1;Decidual stromal cells: 148.2;Endometrial stromal cells: 167.7;Ependymal cells: 288.7;Esophageal suprabasal cells: 147.6;Lymphatic endothelial cells: 164.9;Ocular epithelial cells: 299.3;Retinal pigment epithelial cells: 260.0;Suprabasal keratinocytes: 297.7;Vascular endothelial cells: 164.5" "Group enriched" "Detected in many" 7 "astrocyte: 592.6;Bergmann glia: 287.4;ependymal cell: 388.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 382.5;testis cancer: 417.8" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB010753, HPA035097, HPA047551, HPA069245" Enhanced Supported Approved "Nucleoplasm,Vesicles,Cell Junctions" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 39: Astrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 35 "Vesicles, Cell Junctions" Nucleoplasm "CAB010753: , HPA035097: , HPA047551: , HPA069245: " "unprognostic (7.85e-3)" "unprognostic (4.02e-2)" "unprognostic (1.95e-2)" "unprognostic (1.57e-2)" "unprognostic (1.04e-1)" "unprognostic (1.52e-1)" "unprognostic (1.87e-2)" "potential prognostic unfavorable (6.63e-4)" "unprognostic (5.77e-2)" "unprognostic (1.08e-1)" "potential prognostic favorable (3.97e-5)" "unprognostic (3.94e-3)" "unprognostic (2.09e-1)" "unprognostic (7.45e-2)" "unprognostic (1.93e-1)" "unprognostic (4.58e-2)" "unprognostic (3.00e-2)" "unprognostic (2.82e-1)" "unprognostic (2.40e-1)" "unprognostic (1.43e-1)" "unprognostic (4.59e-2)" "unprognostic (5.51e-2)" "unprognostic (1.40e-2)" "unprognostic (4.80e-2)" "unprognostic (4.13e-2)" "unprognostic (1.13e-1)" "unprognostic (5.55e-2)" "potential prognostic unfavorable (1.44e-5)" "unprognostic (3.41e-1)" "unprognostic (4.44e-2)" "unprognostic (1.91e-1)" GJA10 CX62 ENSG00000135355 "Gap junction protein alpha 10" Q969M2 6 89894469-89921760 "Predicted membrane proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "Testicular Germ Cell Tumor (TCGA): 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA021145 Uncertain NA NA "Cluster 46: Lymphoma - Humoral immune response" "Cluster 102: Non-specific - Mixed function" "HPA021145: " "unprognostic (1.50e-1)" GJA3 "CX46, CZP3" ENSG00000121743 "Gap junction protein alpha 3" Q9Y6H8 13 20138255-20161052 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 7.3;parathyroid gland: 3.8;placenta: 2.3" "Cell type enhanced" "Detected in some" "B-cells: 2.4;Basal keratinocytes: 2.3;Cardiomyocytes: 11.1;Differentiating spermatogonia: 2.6;Esophageal basal cells: 2.5;Pancreatic islet cells: 5.2;Podocytes: 15.2;Undifferentiated spermatogonia: 8.5" "Cell type enhanced" "Detected in single" "medium spiny neuron: 1.8" "Cancer enhanced" "Detected in some" "Skin Cutaneous Melanoma (TCGA): 4.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 5.7" "Adipose visceral - Mesothelial cells, Kidney - Podocytes, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" HPA014821 Supported NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 10 "HPA014821: " "unprognostic (1.10e-1)" "unprognostic (6.35e-3)" "unprognostic (2.73e-2)" "unprognostic (1.93e-1)" "unprognostic (2.44e-1)" GJA4 CX37 ENSG00000187513 "Gap junction protein alpha 4" P35212 1 34792999-34795747 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 107.0" "Cell type enhanced" "Detected in some" "Fallopian secretory cells: 101.3;Fallopian tube ciliated cells: 87.8;Hepatic stellate cells: 38.7;Lymphatic endothelial cells: 79.4;Megakaryocyte progenitors: 36.8;Megakaryocytes: 55.6;Pericytes: 370.1;Platelets: 38.1;Vascular endothelial cells: 59.4;Vascular smooth muscle cells: 244.2" "Group enriched" "Detected in some" 10 "pericyte: 92.0;vascular associated smooth muscle cell: 76.3" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 64.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 2.0;ovarian cancer: 1.6" "Breast - Endothelial cells, Colon - Endothelial cells, Minor Salivary Gland - Endothelial cells, Prostate - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047981 Approved NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 103: Non-specific - Basic cellular processes" 6 "HPA047981: " "unprognostic (5.82e-2)" "unprognostic (4.80e-2)" "unprognostic (3.73e-1)" "unprognostic (1.11e-1)" "unprognostic (9.47e-3)" "unprognostic (9.28e-2)" "unprognostic (1.19e-1)" "unprognostic (1.36e-1)" "unprognostic (5.65e-3)" "unprognostic (8.58e-2)" "validated prognostic favorable (6.05e-5)" "validated prognostic favorable (1.66e-4)" "potential prognostic unfavorable (1.10e-4)" "potential prognostic favorable (6.90e-5)" "unprognostic (2.59e-2)" "unprognostic (1.79e-1)" "unprognostic (7.25e-2)" "unprognostic (6.69e-3)" "unprognostic (3.52e-1)" "unprognostic (1.25e-1)" "unprognostic (4.84e-2)" "unprognostic (6.15e-2)" "unprognostic (1.05e-1)" "unprognostic (2.70e-2)" "unprognostic (1.20e-2)" "unprognostic (1.40e-1)" "unprognostic (7.75e-2)" "unprognostic (5.81e-2)" "unprognostic (1.52e-1)" "unprognostic (1.28e-2)" "unprognostic (1.80e-1)" GJA5 CX40 ENSG00000265107 "Gap junction protein alpha 5" P36382 1 147756199-147773362 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Atrial fibrillation, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 80.3" "Group enriched" "Detected in some" 7 "Cytotrophoblasts: 160.2;Extravillous trophoblasts: 455.5;Migrating cytotrophoblasts: 210.4" "Group enriched" "Detected in some" 24 "endothelial cell: 25.0;pericyte: 18.6;vascular associated smooth muscle cell: 20.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder cancer: 23.9;breast cancer: 14.8" "Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB013080, HPA071370" Enhanced NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 28 "CAB013080: , HPA071370: " "unprognostic (3.66e-2)" "unprognostic (1.08e-1)" "unprognostic (5.00e-1)" "unprognostic (6.50e-3)" "unprognostic (3.83e-2)" "unprognostic (9.68e-2)" "unprognostic (9.76e-3)" "unprognostic (8.31e-2)" "unprognostic (1.09e-1)" "validated prognostic favorable (1.22e-8)" "validated prognostic favorable (4.61e-5)" "potential prognostic unfavorable (1.22e-6)" "unprognostic (3.72e-3)" "unprognostic (1.15e-1)" "unprognostic (4.08e-2)" "unprognostic (3.75e-1)" "potential prognostic unfavorable (7.29e-4)" "unprognostic (4.73e-2)" "unprognostic (6.18e-2)" "unprognostic (3.79e-2)" "unprognostic (7.72e-3)" "unprognostic (1.31e-2)" "unprognostic (5.23e-2)" "unprognostic (1.51e-1)" "unprognostic (9.18e-2)" "unprognostic (9.07e-2)" "unprognostic (9.78e-2)" "unprognostic (1.38e-2)" GJA8 "CAE, CAE1, CX50, CZP1" ENSG00000121634 "Gap junction protein alpha 8" P48165 1 147902795-147909269 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 52 "testis: 5.5" "Cell type enriched" "Detected in some" 9 "Late primary spermatocytes: 82.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA014715, HPA062940" Enhanced NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 15: Kidney cancer - Membrane components" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 108 "HPA014715: , HPA062940: " GJA9 "CX58, CX59, GJA10" ENSG00000131233 "Gap junction protein alpha 9" P57773 1 38874069-38881587 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" HPA067850 Uncertain NA NA "Cluster 47: Endothelial cells - Vasculature" "Cluster 10: Ciliated cells - Ion channel activity" "HPA067850: " "unprognostic (1.84e-1)" GJB1 "CMTX, CMTX1, CX32" ENSG00000169562 "Gap junction protein beta 1" P08034 X 71212811-71225516 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Charcot-Marie-Tooth disease, Dejerine-Sottas syndrome, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 181.3;liver: 374.9;pancreas: 112.8" "Cell type enhanced" "Detected in many" "Breast lactating cells: 43.7;Cholangiocytes: 111.9;Colonocytes: 64.7;Enteric stem cells: 63.3;Enteric transient amplifying cells: 75.5;Enterocytes: 103.2;Epididymal efferent duct absorptive cells: 60.0;Epididymal principal cells: 75.2;Hepatocytes: 335.9;Melanocytes: 44.3;Oligodendrocytes: 65.1;Pancreatic acinar cells: 41.2" "Cell type enriched" "Detected in some" 5 "oligodendrocyte: 102.4" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 288.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 43.3;skin cancer: 83.8" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB012994 Uncertain NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 30: White matter - Myelination" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 93: Hepatocytes - Bile production & excretion" 41 "CAB012994: " "unprognostic (4.46e-2)" "unprognostic (5.00e-3)" "unprognostic (1.12e-1)" "unprognostic (9.80e-2)" "unprognostic (1.03e-1)" "unprognostic (2.06e-1)" "unprognostic (3.53e-1)" "unprognostic (2.68e-1)" "unprognostic (9.37e-2)" "validated prognostic favorable (1.76e-9)" "validated prognostic favorable (1.87e-4)" "unprognostic (3.52e-3)" "unprognostic (4.61e-1)" "unprognostic (2.61e-1)" "unprognostic (6.01e-2)" "unprognostic (1.94e-2)" "unprognostic (1.04e-2)" "unprognostic (6.43e-2)" "unprognostic (6.36e-3)" "unprognostic (1.55e-2)" "unprognostic (4.13e-3)" "unprognostic (1.49e-1)" "unprognostic (8.47e-2)" "unprognostic (3.18e-1)" "unprognostic (1.11e-1)" "unprognostic (1.40e-2)" "unprognostic (3.80e-1)" "unprognostic (8.92e-2)" GJB2 "CX26, DFNA3, DFNB1, NSRD1" ENSG00000165474 "Gap junction protein beta 2" P29033 13 20187463-20192938 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Hearing "Deafness, Disease variant, Ectodermal dysplasia, Ichthyosis, Non-syndromic deafness, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "cervix: 418.8;esophagus: 779.9;vagina: 501.5" "Group enriched" "Detected in many" 6 "Esophageal apical cells: 5411.8;Esophageal suprabasal cells: 1989.0" "Cell type enriched" "Detected in some" 15 "fibroblast: 20.4" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 656.4" "Region enhanced" "Detected in many" "thalamus: 15.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 104.9" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB013093, HPA014362" Uncertain Approved Mitochondria NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 39 Mitochondria "CAB013093: , HPA014362: " "unprognostic (2.46e-1)" "unprognostic (1.32e-1)" "unprognostic (7.55e-2)" "unprognostic (1.16e-3)" "unprognostic (2.02e-1)" "unprognostic (7.11e-2)" "potential prognostic unfavorable (2.67e-4)" "unprognostic (1.02e-3)" "unprognostic (1.17e-1)" "potential prognostic unfavorable (5.80e-5)" "unprognostic (4.87e-2)" "unprognostic (2.07e-1)" "unprognostic (3.41e-2)" "unprognostic (1.69e-1)" "potential prognostic unfavorable (1.45e-5)" "unprognostic (6.73e-3)" "unprognostic (7.70e-3)" "unprognostic (2.02e-2)" "unprognostic (3.44e-3)" "unprognostic (1.15e-2)" "potential prognostic unfavorable (5.35e-4)" "unprognostic (7.73e-2)" "unprognostic (3.22e-2)" "unprognostic (1.43e-2)" "unprognostic (1.89e-1)" "unprognostic (6.54e-2)" "unprognostic (8.97e-3)" "unprognostic (2.99e-1)" "unprognostic (3.17e-3)" "unprognostic (9.39e-2)" GJB3 "CX31, DFNA2, EKV" ENSG00000188910 "Gap junction protein beta 3" O75712 1 34781214-34786369 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Deafness, Disease variant, Non-syndromic deafness, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 75.8;skin 1: 139.2" "Group enriched" "Detected in many" 5 "Basal keratinocytes: 113.0;Esophageal apical cells: 246.4;Esophageal basal cells: 189.9;Esophageal suprabasal cells: 241.6;Ocular epithelial cells: 146.0;Suprabasal keratinocytes: 147.5" "Cell type enriched" "Detected in some" 4 "cerebellar inhibitory: 6.1" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 95.2;Head and Neck Squamous Cell Carcinoma (TCGA): 105.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA074472 Supported "Vesicles,Cell Junctions" NA NA "Cluster 58: Skin - Keratinization" "Cluster 15: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 13 "Vesicles, Cell Junctions" "HPA074472: " "unprognostic (1.48e-1)" "potential prognostic favorable (7.25e-4)" "unprognostic (2.14e-1)" "unprognostic (8.27e-2)" "unprognostic (1.95e-1)" "unprognostic (1.89e-1)" "unprognostic (1.52e-2)" "unprognostic (2.35e-2)" "unprognostic (3.26e-1)" "potential prognostic unfavorable (6.18e-8)" "unprognostic (2.72e-2)" "unprognostic (3.13e-1)" "unprognostic (1.76e-2)" "unprognostic (9.99e-2)" "unprognostic (1.12e-1)" "potential prognostic unfavorable (1.22e-4)" "unprognostic (2.62e-3)" "unprognostic (6.53e-2)" "unprognostic (4.15e-2)" "unprognostic (9.69e-2)" "unprognostic (8.32e-2)" "unprognostic (9.09e-2)" "unprognostic (1.51e-1)" "unprognostic (1.57e-2)" "unprognostic (2.33e-1)" GJB4 CX30.3 ENSG00000189433 "Gap junction protein beta 4" Q9NTQ9 1 34759740-34762327 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skin 1: 58.6" "Group enriched" "Detected in some" 4 "Esophageal apical cells: 31.6;Ocular epithelial cells: 105.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 18.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 10.9;pancreatic cancer: 11.1" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA055112, HPA073904" Enhanced Supported "Cell Junctions" NA NA "Cluster 37: Skin - Keratinization" "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 8 "Cell Junctions" "HPA055112: , HPA073904: " "unprognostic (2.85e-1)" "unprognostic (3.43e-2)" "unprognostic (1.12e-2)" "unprognostic (1.23e-1)" "unprognostic (2.43e-1)" "unprognostic (1.45e-1)" "unprognostic (9.41e-3)" "unprognostic (2.42e-3)" "unprognostic (3.07e-1)" "unprognostic (1.98e-1)" "potential prognostic unfavorable (1.04e-4)" "unprognostic (1.67e-2)" "unprognostic (1.04e-1)" "unprognostic (1.58e-1)" "unprognostic (1.80e-1)" "unprognostic (2.40e-1)" "unprognostic (2.97e-3)" GJB5 CX31.1 ENSG00000189280 "Gap junction protein beta 5" O95377 1 34755047-34758512 "Cancer-related genes, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 98.0;skin 1: 90.6;vagina: 33.8" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 51.5;Esophageal apical cells: 421.8;Esophageal basal cells: 146.2;Esophageal suprabasal cells: 302.1;Ocular epithelial cells: 58.0;Suprabasal keratinocytes: 101.9" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "Bladder Urothelial Carcinoma (TCGA): 40.1;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 72.4;Head and Neck Squamous Cell Carcinoma (TCGA): 85.9;Lung Squamous Cell Carcinoma (TCGA): 37.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 47.7;head and neck cancer: 51.5" "Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary gland basal cells, Skin - Keratinocyte (other), Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA038146 Uncertain NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 32 "HPA038146: " "unprognostic (4.43e-2)" "unprognostic (2.64e-1)" "unprognostic (5.92e-2)" "unprognostic (2.25e-2)" "unprognostic (2.87e-1)" "unprognostic (3.08e-1)" "unprognostic (1.22e-1)" "unprognostic (1.63e-2)" "unprognostic (2.22e-1)" "unprognostic (1.67e-2)" "unprognostic (8.64e-3)" "unprognostic (2.05e-2)" "unprognostic (1.26e-1)" "unprognostic (1.16e-1)" "unprognostic (2.47e-1)" "potential prognostic unfavorable (1.25e-4)" "unprognostic (2.62e-2)" "unprognostic (2.48e-1)" "unprognostic (8.15e-2)" "unprognostic (2.32e-2)" "unprognostic (2.73e-1)" "unprognostic (1.92e-1)" "unprognostic (5.55e-3)" "unprognostic (1.07e-1)" "unprognostic (3.57e-1)" GJB6 "CX30, DFNA3, ED2, EDH, HED" ENSG00000121742 "Gap junction protein beta 6" O95452 13 20221962-20232365 "Disease related genes, Human disease related genes, Predicted membrane proteins" Hearing "Deafness, Disease variant, Ectodermal dysplasia, Non-syndromic deafness, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 159.8;esophagus: 212.4;vagina: 163.9" "Cell type enriched" "Detected in some" 4 "Esophageal apical cells: 1619.9" "Group enriched" "Detected in some" 27 "astrocyte: 82.3;fibroblast: 27.3" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 261.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 2.6" "Lineage enriched" "Detected in single" 5 "T-cells: 2.6" "Group enriched" "Detected in many" 5 "Bladder cancer: 34.8;cervical cancer: 81.6;Esophageal cancer: 26.2;Gastric cancer: 21.1;head and neck cancer: 45.4" "Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014846 Supported "Cell Junctions" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 11 "Cell Junctions" "HPA014846: " "unprognostic (8.76e-2)" "unprognostic (1.07e-1)" "unprognostic (1.24e-1)" "unprognostic (5.95e-2)" "unprognostic (2.25e-1)" "unprognostic (1.95e-1)" "unprognostic (1.60e-1)" "unprognostic (1.56e-2)" "unprognostic (4.44e-3)" "unprognostic (3.34e-3)" "unprognostic (1.90e-2)" "unprognostic (1.02e-1)" "unprognostic (1.14e-2)" "unprognostic (3.08e-1)" "unprognostic (3.27e-1)" "unprognostic (1.28e-2)" "potential prognostic unfavorable (1.13e-4)" "unprognostic (8.57e-2)" "unprognostic (2.17e-1)" "unprognostic (2.21e-1)" "unprognostic (3.41e-3)" "unprognostic (1.66e-2)" GJB7 "bA136M9.1, CX25" ENSG00000164411 "Gap junction protein beta 7" Q6PEY0 6 87282980-87329278 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "fallopian tube: 6.6;pituitary gland: 5.0;placenta: 2.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 32.9;Cytotrophoblasts: 24.6;Endometrial ciliated cells: 21.2;Epididymal efferent duct ciliated cells: 29.8;Fallopian tube ciliated cells: 23.1;Gonadotrophs: 83.4;Migrating cytotrophoblasts: 16.2;Respiratory ciliated cells: 21.1;Syncytiotrophoblasts: 14.9;Thymocytes: 16.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Esophageal cancer: 2.2" "Lung - Respiratory ciliated cells, Pituitary gland - Gonadotropes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" HPA014392 Approved "Plasma membrane,Cytosol" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 37: Neurons - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 63: Cytotrophoblasts - Basic cellular functions" "Plasma membrane, Cytosol" "HPA014392: " "unprognostic (1.71e-1)" "unprognostic (2.01e-1)" "unprognostic (1.33e-2)" "unprognostic (8.32e-2)" "unprognostic (3.63e-2)" "unprognostic (7.65e-2)" "unprognostic (1.28e-1)" GJC1 "CX45, GJA7" ENSG00000182963 "Gap junction protein gamma 1" P36383 17 44798448-44830816 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 37.5" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 48.6;Early primary spermatocytes: 35.0;Endometrial stromal cells: 28.2;Pericytes: 192.9;Schwann cells: 40.9;Smooth muscle cells: 75.0;Vascular smooth muscle cells: 78.1" "Group enriched" "Detected in many" 17 "pericyte: 520.7;vascular associated smooth muscle cell: 200.1" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 27.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.9" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.9" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adrenal gland - Endothelial cells, Minor Salivary Gland - Endothelial cells, Prostate - Smooth muscle cells, Skeletal muscle - Endothelial cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014005 Supported "Nucleoplasm,Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 15: Non-specific - Transcription" "Cluster 72: Neuronal - Signal transduction" "Cluster 110: Mural cells - ECM organization" 5 "Plasma membrane" "Nucleoplasm, Endoplasmic reticulum" "HPA014005: " "unprognostic (1.56e-1)" "unprognostic (7.54e-3)" "unprognostic (2.57e-1)" "unprognostic (8.76e-2)" "unprognostic (3.62e-2)" "unprognostic (1.62e-1)" "unprognostic (1.31e-1)" "unprognostic (7.05e-2)" "unprognostic (1.14e-1)" "unprognostic (6.98e-2)" "unprognostic (5.96e-3)" "potential prognostic favorable (2.88e-4)" "potential prognostic unfavorable (5.78e-6)" "unprognostic (3.46e-2)" "unprognostic (2.51e-1)" "unprognostic (2.20e-2)" "potential prognostic unfavorable (1.35e-5)" "unprognostic (6.08e-2)" "unprognostic (2.89e-3)" "unprognostic (2.56e-2)" "unprognostic (1.34e-1)" "unprognostic (3.36e-1)" "unprognostic (1.07e-2)" "unprognostic (2.84e-1)" "unprognostic (9.53e-2)" "unprognostic (1.63e-2)" "unprognostic (4.36e-2)" "unprognostic (8.00e-3)" "unprognostic (1.46e-1)" "unprognostic (6.46e-2)" "unprognostic (5.91e-2)" GJC2 "CX46.6, CX47, GJA12, SPG44" ENSG00000198835 "Gap junction protein gamma 2" Q5T442 1 228149930-228159826 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Hereditary spastic paraplegia, Leukodystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "brain: 67.0" "Group enriched" "Detected in many" 4 "Lymphatic endothelial cells: 58.3;Oligodendrocytes: 41.1" "Group enriched" "Detected in many" 14 "committed oligodendrocyte precursor: 19.0;oligodendrocyte: 61.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Region enhanced" "Detected in all" "white matter: 105.5" "Low region specificity" "Detected in all" HPA069619 Supported "Plasma membrane,Cytosol" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "Plasma membrane, Cytosol" "HPA069619: " "unprognostic (1.77e-1)" "unprognostic (1.02e-1)" "unprognostic (1.12e-1)" "unprognostic (3.20e-3)" "unprognostic (1.63e-1)" "unprognostic (7.88e-2)" "unprognostic (2.78e-1)" "unprognostic (1.11e-3)" "unprognostic (1.75e-1)" "unprognostic (1.46e-1)" "unprognostic (1.57e-1)" "unprognostic (1.53e-1)" "unprognostic (3.81e-2)" "unprognostic (6.68e-2)" "unprognostic (9.89e-2)" "unprognostic (2.26e-2)" "unprognostic (2.79e-2)" "unprognostic (1.52e-1)" "unprognostic (2.33e-1)" "unprognostic (9.17e-2)" "unprognostic (5.56e-2)" "unprognostic (8.03e-2)" "unprognostic (2.51e-1)" "unprognostic (3.13e-2)" GJC3 "CX30.2, GJE1" ENSG00000176402 "Gap junction protein gamma 3" Q8NFK1 7 99923266-99929620 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 8.0;pancreas: 10.5;salivary gland: 11.6" "Cell type enhanced" "Detected in some" "Breast hormone-responsive cells: 43.8;Breast secretory cells: 51.9;Lacrimal acinar cells: 160.3;Pancreatic acinar cells: 18.6;Prostatic glandular cells: 17.2;Salivary acinar cells: 29.5;Schwann cells: 44.6;Submucosal glandular cells: 18.3" "Low cell type specificity" "Detected in some" "Group enriched" "Detected in some" 5 "Breast Invasive Carcinoma (TCGA): 7.3;Prostate Adenocarcinoma (TCGA): 6.2;Skin Cutaneous Melanoma (TCGA): 5.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015024 Uncertain NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 24: Non-specific - Unknown function" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 2 "HPA015024: " "unprognostic (7.27e-2)" "unprognostic (1.47e-1)" "unprognostic (1.14e-2)" "unprognostic (1.91e-1)" "unprognostic (2.52e-1)" "unprognostic (8.14e-2)" "unprognostic (2.16e-1)" "unprognostic (5.02e-1)" "unprognostic (8.49e-2)" "unprognostic (4.49e-1)" GJD2 "CX36, GJA9" ENSG00000159248 "Gap junction protein delta 2" Q9UKL4 15 34751032-34754998 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 5.6;pituitary gland: 7.3;retina: 19.8" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 21.3;Cone photoreceptor cells: 33.1;Corticotrophs: 5.3;Pancreatic islet cells: 15.6;Retinal bipolar cells: 5.9;Rod photoreceptor cells: 10.0;Somatotrophs: 19.6" "Cell type enhanced" "Detected in many" "CGE interneuron: 9.5;LAMP5-LHX6 and Chandelier: 12.8;MGE interneuron: 9.7" "Group enriched" "Detected in some" 17 "Kidney Chromophobe (TCGA): 1.6;Pancreatic Adenocarcinoma (TCGA): 5.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Neuroblastoma: 3.8;Sarcoma: 1.3;testis cancer: 1.9" "Adrenal gland - Adrenal medulla cells, Kidney - Intercalated cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 24: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 1 "unprognostic (2.00e-1)" "unprognostic (3.73e-2)" "unprognostic (8.57e-2)" GJD3 "Cx30.2, CX31.9, GJA11, GJC1" ENSG00000183153 "Gap junction protein delta 3" Q8N144 17 40360652-40364737 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Endometrial luminal cells: 2.5;Endometrial stromal cells: 2.2;Epicardial cells: 4.5;Epididymal basal cells: 2.0;Fibroblasts: 1.8;Lymphatic endothelial cells: 10.1;Pericytes: 3.3;Vascular endothelial cells: 2.4" "Cell type enriched" "Detected in some" 4 "fibroblast: 4.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Fibroblasts" "Not detected" "Not detected" NA NA "Cluster 5: Spleen - Immune response" "Cluster 1: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 4 "unprognostic (1.90e-2)" "unprognostic (6.31e-2)" "unprognostic (6.54e-2)" "unprognostic (2.31e-1)" "unprognostic (2.46e-1)" "unprognostic (3.71e-1)" "unprognostic (3.80e-3)" "potential prognostic unfavorable (5.69e-4)" "unprognostic (3.58e-2)" "unprognostic (1.05e-1)" "unprognostic (2.77e-2)" "unprognostic (4.42e-2)" "unprognostic (3.30e-3)" "unprognostic (6.51e-2)" "unprognostic (2.36e-1)" "unprognostic (4.49e-2)" "unprognostic (2.92e-1)" "unprognostic (2.39e-1)" "unprognostic (1.08e-1)" "unprognostic (3.67e-2)" "unprognostic (5.84e-2)" "unprognostic (1.01e-1)" "unprognostic (5.48e-2)" "unprognostic (1.05e-1)" "unprognostic (5.06e-3)" "unprognostic (3.34e-2)" "unprognostic (1.41e-1)" "unprognostic (2.44e-1)" "unprognostic (1.08e-1)" "unprognostic (5.01e-2)" GJD4 "CX40.1, FLJ90023" ENSG00000177291 "Gap junction protein delta 4" Q96KN9 10 35605341-35608935 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Respiratory deuterosomal cells: 1.0;Thymic myoid cells: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.5" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA038266 Uncertain NA NA "Cluster 48: Non-specific - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "HPA038266: " "unprognostic (2.77e-1)" "unprognostic (2.19e-2)" GJE1 CX23 ENSG00000203733 "Gap junction protein epsilon 1" A6NN92 6 142132925-142135358 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA014916 Uncertain NA NA "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "HPA014916: " GK "GK1, GKD" ENSG00000198814 "Glycerol kinase" P32189 X 30653359-30731462 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycerol metabolism" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 82.3;kidney: 98.4;liver: 66.9" "Cell type enriched" "Detected in many" 4 "Neutrophils: 3826.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 8 "neutrophil: 160.1" "Lineage enriched" "Detected in all" 8 "granulocytes: 160.1" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Minor Salivary Gland - Minor salivary glandular cells, Spleen - Neutrophils_2, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" HPA060687 Supported NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 12: Non-specific - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 5 "HPA060687: " "unprognostic (1.99e-1)" "unprognostic (2.37e-2)" "unprognostic (3.67e-2)" "unprognostic (1.28e-2)" "unprognostic (5.32e-2)" "unprognostic (1.01e-1)" "unprognostic (4.68e-2)" "unprognostic (5.42e-2)" "unprognostic (2.36e-2)" "unprognostic (3.51e-1)" "potential prognostic favorable (7.19e-8)" "unprognostic (1.64e-2)" "unprognostic (1.23e-1)" "unprognostic (1.25e-2)" "unprognostic (2.45e-2)" "unprognostic (3.62e-2)" "unprognostic (1.33e-1)" "unprognostic (2.10e-1)" "unprognostic (5.58e-2)" "unprognostic (1.23e-1)" "unprognostic (3.48e-2)" "unprognostic (3.26e-1)" "unprognostic (3.06e-2)" "unprognostic (6.38e-3)" "unprognostic (3.22e-2)" "unprognostic (2.66e-2)" "unprognostic (1.50e-2)" "unprognostic (1.99e-1)" "unprognostic (1.63e-2)" "unprognostic (1.07e-2)" "unprognostic (2.71e-2)" GK2 "GKP2, GKTA" ENSG00000196475 "Glycerol kinase 2" Q14410 4 79406361-79408228 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Differentiation, Glycerol metabolism, Spermatogenesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 837 "testis: 83.7" "Group enriched" "Detected in some" 31 "Early spermatids: 541.9;Late primary spermatocytes: 671.1;Late spermatids: 205.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 1.1" HPA060687 Uncertain NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 1 "HPA060687: " GK3P "GKP3, GKTB" ENSG00000229894 "Glycerol kinase 3 pseudogene" Q14409 4 165277807-165279704 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycerol metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 28 "testis: 12.3" "Group enriched" "Detected in some" 20 "Early spermatids: 79.7;Late primary spermatocytes: 75.1;Late spermatids: 34.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" HPA060687 Uncertain NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 34: Non-specific - Mixed function" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 1 "HPA060687: " "unprognostic (5.34e-2)" GK5 MGC40579 ENSG00000175066 "Glycerol kinase 5" Q6ZS86 3 142157527-142225592 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycerol metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 267.0;Prostatic glandular cells: 266.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Sebaceous gland cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA042606, HPA057998" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 77: Intestine - Digestion" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" "Nucleoplasm, Cytosol" "HPA042606: , HPA057998: " "unprognostic (9.46e-2)" "unprognostic (1.29e-1)" "unprognostic (2.12e-1)" "unprognostic (1.55e-1)" "unprognostic (5.10e-2)" "unprognostic (1.60e-2)" "unprognostic (3.69e-1)" "unprognostic (2.22e-1)" "unprognostic (1.54e-2)" "unprognostic (2.32e-3)" "unprognostic (6.04e-2)" "unprognostic (1.25e-2)" "unprognostic (4.32e-2)" "unprognostic (1.18e-2)" "unprognostic (1.26e-1)" "unprognostic (2.60e-1)" "unprognostic (1.09e-1)" "unprognostic (1.10e-1)" "unprognostic (1.98e-2)" "unprognostic (2.44e-1)" "unprognostic (5.16e-1)" "unprognostic (1.62e-2)" "unprognostic (8.04e-2)" "unprognostic (2.15e-1)" "unprognostic (2.70e-2)" "unprognostic (2.04e-1)" "unprognostic (3.81e-3)" "unprognostic (8.84e-3)" "unprognostic (1.66e-1)" "unprognostic (9.71e-2)" "unprognostic (1.07e-1)" GKAP1 "FKSG21, GKAP42" ENSG00000165113 "G kinase anchoring protein 1" Q5VSY0 9 83739425-83829516 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "skeletal muscle: 47.1;testis: 187.3" "Group enriched" "Detected in many" 5 "Early spermatids: 1297.6;Late primary spermatocytes: 1878.8;Late spermatids: 667.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035117, HPA035118, HPA066173" Enhanced Supported Approved "Centriolar satellite,Cytosol" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 67: Testis - Mixed function" "Cluster 25: Non-specific - Transcription" "Cluster 11: Neuronal - Sensory perception" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 14 "Centriolar satellite, Cytosol" "HPA035117: , HPA035118: , HPA066173: " "unprognostic (1.56e-1)" "unprognostic (4.29e-2)" "unprognostic (2.58e-1)" "unprognostic (3.17e-1)" "unprognostic (1.79e-1)" "unprognostic (2.25e-1)" "unprognostic (3.65e-1)" "unprognostic (1.25e-2)" "unprognostic (1.35e-1)" "unprognostic (3.10e-1)" "validated prognostic favorable (8.86e-6)" "validated prognostic favorable (2.52e-4)" "unprognostic (3.75e-2)" "unprognostic (6.55e-3)" "unprognostic (1.74e-1)" "unprognostic (8.87e-3)" "unprognostic (1.44e-2)" "unprognostic (2.42e-1)" "unprognostic (1.04e-1)" "unprognostic (6.18e-3)" "unprognostic (1.11e-1)" "potential prognostic favorable (6.60e-4)" "unprognostic (5.60e-2)" "unprognostic (1.51e-1)" "unprognostic (6.16e-2)" "unprognostic (7.13e-2)" "unprognostic (2.46e-1)" "unprognostic (1.00e-1)" "unprognostic (1.15e-2)" "unprognostic (1.47e-1)" "unprognostic (1.71e-1)" GKN1 "AMP18, BRICD1, CA11" ENSG00000169605 "Gastrokine 1" Q9NS71 2 68974573-68980980 "Plasma proteins, Predicted secreted proteins, Transporters" Mitogen "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1850 "stomach 1: 35310.8" "Cell type enriched" "Detected in some" 150 "Foveolar cells: 48851.1" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 95 "Stomach Adenocarcinoma (TCGA): 524.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 26 "Bladder cancer: 18.4" "Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA047684 Enhanced "Secreted to digestive system" Other NA NA 8000000 "Cluster 60: Stomach - Digestion" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 68: Foveolar cells - Mucosal defense" 17 "HPA047684: " "unprognostic (2.94e-2)" "unprognostic (2.23e-1)" "potential prognostic unfavorable (1.45e-4)" "unprognostic (9.34e-2)" "unprognostic (3.13e-1)" GKN2 "blottin, BRICD1B, GDDR, PRO813, TFIZ1, VLTI465" ENSG00000183607 "Gastrokine 2" Q86XP6 2 68945232-68952893 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 57 "stomach 1: 4351.2" "Cell type enriched" "Detected in some" 18 "Foveolar cells: 8392.2" "Not detected" "Not detected" "Group enriched" "Detected in some" 32 "Lung Adenocarcinoma (TCGA): 37.1;Stomach Adenocarcinoma (TCGA): 140.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "ovarian cancer: 3.0;pancreatic cancer: 4.6;prostate cancer: 1.8;thyroid cancer: 4.3" "Lung - Alveolar cells type 2, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA057765 Enhanced "Secreted to digestive system" "No annotated function" NA NA "Cluster 60: Stomach - Digestion" "Cluster 15: Kidney cancer - Membrane components" "Cluster 68: Foveolar cells - Mucosal defense" 1 "HPA057765: " "unprognostic (2.11e-2)" "unprognostic (9.23e-3)" "unprognostic (1.11e-2)" "unprognostic (4.99e-2)" "potential prognostic unfavorable (9.86e-5)" "unprognostic (2.85e-1)" GLA GALA ENSG00000102393 "Galactosidase alpha" P06280 X 101393273-101408012 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" "Glycosidase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "cDC: 332.0;Macrophages: 179.2;Neutrophils: 206.9;Plasma cells: 265.2;Platelets: 427.4;Syncytiotrophoblasts: 209.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000237, HPA000966" Enhanced "Intracellular and membrane" Enzyme NA NA 1200000 "Cluster 40: Monocytes - Innate immune response" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 7: Liver cancer - Metabolism" "Cluster 103: Non-specific - Basic cellular processes" 10 "HPA000237: , HPA000966: " "unprognostic (1.70e-1)" "unprognostic (1.64e-2)" "unprognostic (1.07e-1)" "unprognostic (2.88e-2)" "unprognostic (1.08e-2)" "unprognostic (2.72e-3)" "unprognostic (7.98e-3)" "unprognostic (9.02e-2)" "unprognostic (4.52e-3)" "unprognostic (1.24e-3)" "unprognostic (4.21e-2)" "unprognostic (7.59e-2)" "unprognostic (2.71e-1)" "validated prognostic unfavorable (1.94e-5)" "validated prognostic unfavorable (3.84e-4)" "unprognostic (3.55e-2)" "unprognostic (6.49e-3)" "unprognostic (1.34e-1)" "unprognostic (1.13e-1)" "unprognostic (9.68e-2)" "unprognostic (3.78e-1)" "unprognostic (1.94e-1)" "unprognostic (5.34e-2)" "unprognostic (3.91e-2)" "unprognostic (2.17e-1)" "unprognostic (4.30e-3)" "unprognostic (2.59e-1)" "unprognostic (2.37e-3)" "unprognostic (2.41e-2)" "unprognostic (7.10e-2)" "unprognostic (2.85e-2)" GLB1 "EBP, ELNR1" ENSG00000170266 "Galactosidase beta 1" P16278 3 32996609-33097202 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant, Gangliosidosis, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adrenal gland - Adrenal cortex cells, Colon - Macrophages, Liver - Hepatocytes, Lung - Macrophages, Spleen - Macrophages, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008382, HPA040610, HPA069503" Enhanced Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" Enzyme NA NA 800000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 22: Epididymis - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 34: Testis cancer - Unknown function" "Cluster 9: T-cells - Adaptive immunity: Regulation" 17 Vesicles "Golgi apparatus" "CAB008382: , HPA040610: , HPA069503: " "unprognostic (2.16e-2)" "unprognostic (2.10e-3)" "unprognostic (2.32e-1)" "potential prognostic unfavorable (2.56e-5)" "unprognostic (4.00e-2)" "unprognostic (3.09e-1)" "unprognostic (3.57e-2)" "unprognostic (7.28e-3)" "unprognostic (3.97e-2)" "unprognostic (4.15e-2)" "unprognostic (2.62e-3)" "potential prognostic unfavorable (4.63e-4)" "unprognostic (2.40e-3)" "potential prognostic unfavorable (4.02e-4)" "unprognostic (1.46e-2)" "unprognostic (6.84e-2)" "unprognostic (1.97e-1)" "unprognostic (2.24e-1)" "unprognostic (2.00e-1)" "unprognostic (2.52e-1)" "unprognostic (1.23e-1)" "unprognostic (2.63e-1)" "unprognostic (1.13e-1)" "unprognostic (2.14e-1)" "unprognostic (2.77e-2)" "unprognostic (2.38e-2)" "unprognostic (3.66e-1)" "unprognostic (1.61e-1)" "unprognostic (1.58e-1)" "unprognostic (2.90e-1)" "unprognostic (9.21e-2)" GLB1L MGC10771 ENSG00000163521 "Galactosidase beta 1 like" Q6UWU2 2 219236598-219245478 "Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 48.9" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 48.0;Ependymal cells: 29.3;Epididymal efferent duct ciliated cells: 34.8;Fallopian tube ciliated cells: 40.8;Late primary spermatocytes: 191.8;Late spermatids: 27.9;Respiratory ciliated cells: 44.7" "Cell type enriched" "Detected in many" 5 "ependymal cell: 38.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043058 Enhanced "Secreted - unknown location" Enzyme NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 69: Skin cancer - ECM organization" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 2 "HPA043058: " "unprognostic (8.91e-2)" "unprognostic (2.27e-2)" "unprognostic (2.80e-1)" "potential prognostic favorable (4.11e-4)" "unprognostic (3.87e-2)" "potential prognostic unfavorable (1.39e-4)" "unprognostic (3.95e-2)" "unprognostic (1.17e-2)" "unprognostic (3.23e-2)" "unprognostic (2.58e-1)" "potential prognostic favorable (5.97e-5)" "unprognostic (7.44e-2)" "unprognostic (5.30e-3)" "unprognostic (1.96e-3)" "unprognostic (1.21e-1)" "unprognostic (1.49e-3)" "unprognostic (2.35e-1)" "unprognostic (1.03e-1)" "unprognostic (1.38e-1)" "unprognostic (1.72e-1)" "unprognostic (1.15e-1)" "unprognostic (2.60e-2)" "unprognostic (1.10e-2)" "unprognostic (3.82e-1)" "unprognostic (1.96e-1)" "unprognostic (7.77e-3)" "unprognostic (3.69e-1)" "unprognostic (1.93e-1)" "unprognostic (7.28e-2)" "unprognostic (3.22e-1)" "unprognostic (1.64e-1)" GLB1L2 ENSG00000149328 "Galactosidase beta 1 like 2" Q8IW92 11 134331874-134378341 "Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 149.1" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 20.7;Decidual stromal cells: 46.3;Ependymal cells: 24.9;Epididymal efferent duct ciliated cells: 25.2;Fallopian tube ciliated cells: 26.1;Respiratory ciliated cells: 25.9;Rod photoreceptor cells: 125.0" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 18.5;ependymal cell: 28.1" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 75.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 3.2;NK-cell: 3.1" "Group enriched" "Detected in many" 25 "NK-cells: 3.1;T-cells: 3.2" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA054808, HPA059955" Uncertain Approved Nucleoplasm,Vesicles "Secreted in other tissues" Enzyme NA NA "Cluster 1: T-cells - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 29: Forebrain - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 79: Photoreceptor cells - Phototransduction" 13 Nucleoplasm Vesicles "HPA054808: , HPA059955: " "unprognostic (1.78e-1)" "unprognostic (1.62e-3)" "unprognostic (1.09e-2)" "unprognostic (3.19e-3)" "unprognostic (4.31e-1)" "unprognostic (6.73e-2)" "unprognostic (6.34e-2)" "unprognostic (3.65e-2)" "unprognostic (2.37e-1)" "unprognostic (3.90e-1)" "potential prognostic favorable (7.88e-4)" "unprognostic (8.14e-2)" "unprognostic (3.85e-3)" "unprognostic (1.62e-3)" "unprognostic (3.64e-2)" "unprognostic (4.16e-3)" "unprognostic (3.28e-2)" "unprognostic (3.53e-1)" "unprognostic (1.61e-1)" "unprognostic (1.04e-1)" "unprognostic (6.39e-2)" "unprognostic (1.06e-3)" "unprognostic (2.48e-1)" "unprognostic (4.91e-2)" "unprognostic (5.13e-2)" "unprognostic (1.55e-1)" "unprognostic (1.43e-2)" "unprognostic (2.44e-1)" "unprognostic (6.07e-3)" "unprognostic (3.64e-2)" GLB1L3 FLJ90231 ENSG00000166105 "Galactosidase beta 1 like 3" Q8NCI6 11 134274245-134319564 "Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "prostate: 7.5;seminal vesicle: 4.1" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 33.5;Brain inhibitory neurons: 30.0;Differentiating spermatogonia: 20.8;Early primary spermatocytes: 11.1;Early spermatids: 13.3;Extravillous trophoblasts: 13.6;Gonadotrophs: 11.2;Late primary spermatocytes: 18.0;Oligodendrocyte progenitor cells: 12.5;Other brain neurons: 21.5;Respiratory basal cells: 10.3;Retinal ganglion cells: 30.9;Sertoli cells: 13.7;Thyrotrophs: 14.8;Undifferentiated spermatogonia: 25.0" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in some" 10 "Lung Adenocarcinoma (TCGA): 7.7;Prostate Adenocarcinoma (TCGA): 15.9" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 11 "gdT-cell: 1.2;memory CD4 T-cell: 3.1;memory CD8 T-cell: 1.9;naive CD4 T-cell: 2.4;naive CD8 T-cell: 1.9;T-reg: 1.5" "Lineage enriched" "Detected in single" 31 "T-cells: 3.1" "Cancer enhanced" "Detected in some" "Neuroblastoma: 3.2" "Adrenal gland - Adrenal medulla cells, Kidney - Proximal tubular cells, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Alpha cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA039916 Uncertain NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 27: Cerebellum - Synaptic function" "Cluster 37: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 35: Neurons - Synaptic function & neurogenesis" "HPA039916: " "unprognostic (1.28e-1)" "unprognostic (2.77e-1)" "unprognostic (8.24e-2)" "unprognostic (5.08e-2)" "unprognostic (5.56e-3)" "unprognostic (6.54e-2)" "unprognostic (1.48e-1)" "unprognostic (4.82e-2)" "unprognostic (2.73e-1)" GLCCI1 "FAM117C, GIG18, TSSN1" ENSG00000106415 "Glucocorticoid induced 1" Q86VQ1 7 7968796-8094272 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 31.4" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 457.4;Oligodendrocyte progenitor cells: 387.5;Plasma cells: 789.3;Renal collecting duct intercalated cells: 468.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Myeloma: 49.0" "Minor Salivary Gland - Plasma cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001674, HPA005987" Approved Approved Nucleoli NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 34: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 44: Plasma cells - Antibody production & secretion" 10 Nucleoli "HPA001674: , HPA005987: " "unprognostic (3.28e-2)" "unprognostic (1.91e-2)" "unprognostic (6.69e-2)" "unprognostic (1.11e-1)" "unprognostic (6.62e-2)" "unprognostic (1.22e-1)" "unprognostic (4.43e-2)" "unprognostic (1.06e-3)" "unprognostic (3.81e-3)" "unprognostic (1.29e-2)" "potential prognostic favorable (1.11e-5)" "unprognostic (1.76e-1)" "unprognostic (2.73e-1)" "unprognostic (1.39e-1)" "unprognostic (5.83e-2)" "unprognostic (7.53e-3)" "unprognostic (2.92e-1)" "unprognostic (9.86e-2)" "unprognostic (9.06e-2)" "unprognostic (1.00e-1)" "unprognostic (4.67e-2)" "unprognostic (6.53e-2)" "unprognostic (4.13e-3)" "unprognostic (1.60e-1)" "unprognostic (2.46e-2)" "unprognostic (1.37e-2)" "unprognostic (2.09e-1)" "unprognostic (2.43e-1)" "unprognostic (1.18e-1)" "unprognostic (2.02e-1)" "unprognostic (3.73e-2)" GLCE "HSEPI, KIAA0836" ENSG00000138604 "Glucuronic acid epimerase" O94923 15 69160584-69272217 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 40.9" "Cell type enhanced" "Detected in all" "Brain excitatory neurons: 200.0;Microglia: 195.9" "Cell type enhanced" "Detected in all" "upper rhombic lip: 513.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 8 "dendritic cells: 1.9;monocytes: 2.3;T-cells: 2.0" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skeletal muscle - Fibroblasts, Stomach - Gastric mucous cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040481, HPA048216" Uncertain Approved Mitochondria NA NA 180000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 27: Cerebellum - Synaptic function" "Cluster 35: Non-specific - DNA binding" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 2 Mitochondria "HPA040481: , HPA048216: " "unprognostic (5.57e-1)" "unprognostic (2.64e-1)" "unprognostic (4.08e-2)" "unprognostic (5.37e-2)" "unprognostic (6.47e-2)" "unprognostic (1.42e-3)" "unprognostic (4.29e-1)" "unprognostic (2.01e-2)" "unprognostic (6.99e-2)" "unprognostic (3.23e-1)" "potential prognostic favorable (2.24e-5)" "unprognostic (3.67e-3)" "unprognostic (3.48e-2)" "unprognostic (1.55e-2)" "unprognostic (6.51e-2)" "unprognostic (1.78e-1)" "unprognostic (2.06e-1)" "unprognostic (1.00e-1)" "unprognostic (1.22e-1)" "unprognostic (3.16e-2)" "unprognostic (7.32e-2)" "unprognostic (5.40e-2)" "unprognostic (7.78e-2)" "unprognostic (1.44e-1)" "potential prognostic favorable (9.56e-4)" "unprognostic (8.17e-2)" "unprognostic (7.57e-2)" "unprognostic (1.16e-1)" "unprognostic (2.78e-1)" "unprognostic (6.79e-2)" "unprognostic (1.59e-1)" GLDC "GCSP, NKH" ENSG00000178445 "Glycine decarboxylase" P23378 9 6532467-6645729 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 172.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 191.3;Distal convoluted tubule cells: 143.2;Extravillous trophoblasts: 79.9;Hepatocytes: 166.4;Migrating cytotrophoblasts: 119.3;Papillary tip epithelial cells: 104.1;Pituitary stem cells: 93.2;Proximal tubule cells: 171.0;Renal collecting duct principal cells: 90.1;Renal connecting tubule cells: 253.3;Retinal pigment epithelial cells: 230.2" "Cell type enhanced" "Detected in many" "oligodendrocyte precursor cell: 71.4" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 115.3;Testicular Germ Cell Tumor (TCGA): 198.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Myeloma: 39.3" "Minor Salivary Gland - Plasma cells, Skin - Sebaceous gland cells, Stomach - Plasma cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002318, HPA052887" Enhanced Supported Nucleoplasm,Mitochondria NA NA 400000 "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 34: Testis cancer - Unknown function" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 4 Mitochondria Nucleoplasm "HPA002318: , HPA052887: " "unprognostic (1.35e-1)" "unprognostic (4.29e-2)" "unprognostic (6.74e-2)" "unprognostic (2.89e-1)" "unprognostic (7.56e-2)" "unprognostic (2.87e-3)" "unprognostic (1.69e-1)" "unprognostic (9.95e-2)" "unprognostic (5.60e-2)" "unprognostic (3.23e-3)" "unprognostic (1.58e-1)" "unprognostic (1.28e-1)" "unprognostic (5.56e-3)" "unprognostic (2.03e-1)" "unprognostic (2.58e-1)" "unprognostic (3.09e-1)" "unprognostic (1.14e-1)" "unprognostic (6.21e-2)" "unprognostic (1.37e-1)" "unprognostic (5.82e-2)" "unprognostic (2.70e-2)" "unprognostic (4.44e-2)" "unprognostic (5.01e-2)" "unprognostic (1.61e-1)" "unprognostic (1.24e-1)" "unprognostic (3.13e-3)" "unprognostic (1.99e-1)" "unprognostic (4.09e-3)" "unprognostic (9.16e-2)" GLDN "CLOM, COLM, colmedin, CRG-L2, UNC-122" ENSG00000186417 Gliomedin Q6ZMI3 15 51341655-51408005 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 17.3;blood vessel: 20.7;brain: 44.1" "Group enriched" "Detected in many" 4 "Microglia: 221.0;Oligodendrocytes: 606.7;Syncytiotrophoblasts: 334.1" "Group enriched" "Detected in many" 7 "central nervous system macrophage: 338.5;committed oligodendrocyte precursor: 230.5;oligodendrocyte: 847.0" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 24.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adrenal gland - Macrophages, Heart muscle - Cardiomyocytes, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA050873, HPA059441" Uncertain Supported "Vesicles,Plasma membrane" "Secreted to extracellular matrix" "Developmental protein" NA NA 400000 "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 80: Oligodendrocytes - Myelination" "Vesicles, Plasma membrane" "HPA050873: , HPA059441: " "unprognostic (3.45e-1)" "unprognostic (4.40e-2)" "unprognostic (2.94e-1)" "unprognostic (7.91e-2)" "unprognostic (1.10e-2)" "unprognostic (2.92e-1)" "unprognostic (1.30e-1)" "unprognostic (1.46e-1)" "unprognostic (1.66e-2)" "potential prognostic unfavorable (2.59e-4)" "unprognostic (2.08e-2)" "unprognostic (5.66e-2)" "unprognostic (1.44e-1)" "unprognostic (2.19e-3)" "unprognostic (1.23e-1)" "unprognostic (1.47e-2)" "unprognostic (1.77e-1)" "unprognostic (3.85e-1)" "unprognostic (6.22e-2)" "unprognostic (1.27e-1)" "unprognostic (4.77e-3)" "unprognostic (5.63e-3)" "unprognostic (2.07e-1)" GLE1 "GLE1L, hGLE1, LCCS1" ENSG00000119392 "GLE1 RNA export mediator" Q53GS7 9 128504655-128543874 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 103.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041689, HPA043538, HPA061560" Supported Supported "Nuclear membrane,Nucleoli,Cytosol" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 24: Neutrophils - Innate immunity signal integration" 56 "Nuclear membrane" "Nucleoli, Cytosol" "HPA041689: , HPA043538: , HPA061560: " "unprognostic (1.44e-1)" "unprognostic (1.50e-2)" "unprognostic (2.56e-1)" "unprognostic (2.56e-1)" "unprognostic (2.58e-1)" "unprognostic (3.96e-3)" "unprognostic (1.57e-1)" "unprognostic (9.78e-2)" "unprognostic (9.22e-2)" "unprognostic (2.90e-2)" "potential prognostic favorable (3.54e-6)" "unprognostic (6.76e-3)" "unprognostic (1.65e-1)" "unprognostic (5.24e-2)" "unprognostic (3.55e-1)" "unprognostic (8.03e-2)" "unprognostic (8.33e-2)" "unprognostic (1.82e-2)" "unprognostic (2.21e-2)" "unprognostic (3.09e-1)" "unprognostic (8.92e-2)" "unprognostic (4.44e-1)" "unprognostic (1.14e-1)" "unprognostic (3.16e-2)" "unprognostic (1.31e-2)" "unprognostic (2.91e-1)" "unprognostic (1.13e-1)" "unprognostic (3.42e-3)" "unprognostic (1.45e-1)" "unprognostic (1.25e-1)" "unprognostic (6.47e-2)" GLG1 "CFR-1, ESL-1, MG-160" ENSG00000090863 "Golgi glycoprotein 1" Q92896 16 74447427-74607144 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Prostate - Fibroblasts, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010815 Supported Supported "Golgi apparatus,Mid piece,Principal piece,End piece" NA NA 900000 "Cluster 33: Non-specific - ATP binding" "Cluster 21: Testis - Mixed function" "Cluster 27: Non-specific - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 13 "Golgi apparatus" "Mid piece, Principal piece, End piece" "HPA010815: " "unprognostic (7.48e-2)" "unprognostic (7.06e-2)" "unprognostic (2.21e-1)" "unprognostic (1.87e-2)" "unprognostic (2.43e-1)" "unprognostic (4.50e-2)" "unprognostic (2.20e-1)" "unprognostic (1.51e-1)" "unprognostic (6.18e-2)" "unprognostic (2.33e-1)" "potential prognostic favorable (8.34e-7)" "unprognostic (2.63e-2)" "unprognostic (3.16e-3)" "potential prognostic unfavorable (1.63e-4)" "unprognostic (1.16e-2)" "unprognostic (1.04e-2)" "unprognostic (3.96e-2)" "unprognostic (1.72e-2)" "unprognostic (1.54e-1)" "unprognostic (3.51e-2)" "unprognostic (2.61e-2)" "unprognostic (1.16e-1)" "unprognostic (5.49e-3)" "unprognostic (1.46e-1)" "unprognostic (1.37e-1)" "unprognostic (1.85e-1)" "unprognostic (2.74e-1)" "unprognostic (1.82e-1)" "unprognostic (9.29e-2)" "unprognostic (2.35e-2)" "unprognostic (2.85e-1)" GLI1 GLI ENSG00000111087 "GLI family zinc finger 1" P08151 12 57459785-57472268 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 10.4" "Group enriched" "Detected in some" 4 "Bergmann glia: 38.0;Leydig cells: 51.2;Peritubular myoid cells: 53.8" "Cell type enriched" "Detected in some" 5 "Bergmann glia: 41.3" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 15.7" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "neutrophil: 1.9" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.9" "Group enriched" "Detected in many" 6 "Bone cancer: 31.1;Brain cancer: 7.8;Rhabdoid: 22.1;Sarcoma: 12.5" "Adrenal gland - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblasts_2, Pituitary gland - Fibroblasts, Testis - Peritubular cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB009460, HPA065172, HPA068903" Uncertain Supported "Nucleoplasm,Primary cilium tip,Basal body,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 75: Ovary - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 94: Gonadal somatic cells - Mixed function" 38 Nucleoplasm "Primary cilium tip, Basal body, Cytosol" "CAB009460: , HPA065172: , HPA068903: " "unprognostic (2.44e-1)" "unprognostic (2.18e-2)" "unprognostic (3.15e-2)" "unprognostic (7.71e-2)" "unprognostic (3.84e-2)" "unprognostic (5.31e-2)" "unprognostic (2.71e-1)" "unprognostic (1.54e-2)" "unprognostic (1.05e-2)" "unprognostic (1.91e-1)" "unprognostic (3.88e-1)" "unprognostic (1.51e-1)" "unprognostic (2.72e-2)" "unprognostic (1.98e-1)" "unprognostic (1.28e-1)" "unprognostic (3.23e-2)" "unprognostic (1.33e-1)" "unprognostic (1.96e-2)" "unprognostic (4.72e-3)" "unprognostic (1.06e-1)" "unprognostic (1.57e-1)" GLI2 "HPE9, THP1, THP2" ENSG00000074047 "GLI family zinc finger 2" P10070 2 120735623-120992653 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Disease variant, Holoprosencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 9.8" "Cell type enhanced" "Detected in many" "Astrocytes: 83.3;Bergmann glia: 188.4;Early spermatids: 58.9;Ependymal cells: 60.1;Epicardial cells: 79.6;Fibro-adipogenic progenitors: 96.8;Hepatic stellate cells: 64.5;Lactotrophs: 87.1;Late spermatids: 84.2;Leydig cells: 103.1;Mesothelial cells: 63.1;Myosatellite cells: 114.9;Ovarian stromal cells: 70.4;Peritubular myoid cells: 118.0;Somatotrophs: 201.9;Thyrotrophs: 83.1" "Group enriched" "Detected in many" 4 "astrocyte: 104.4;Bergmann glia: 181.7;ependymal cell: 65.9;fibroblast: 57.7" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 8.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB008558, HPA074275" Approved Supported "Nucleoplasm,Nucleoli,Centrosome,Basal body" No No "Cluster 75: Ovary - Mixed function" "Cluster 44: Non-specific - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 94: Gonadal somatic cells - Mixed function" 10 Nucleoli "Nucleoplasm, Centrosome, Basal body" "CAB008558: , HPA074275: " "unprognostic (2.99e-1)" "unprognostic (1.91e-2)" "unprognostic (3.71e-2)" "unprognostic (1.26e-1)" "unprognostic (4.55e-2)" "unprognostic (2.58e-1)" "potential prognostic unfavorable (1.65e-5)" "unprognostic (2.25e-1)" "unprognostic (2.65e-1)" "unprognostic (1.13e-2)" "unprognostic (2.84e-1)" "unprognostic (1.80e-1)" "unprognostic (4.81e-3)" "unprognostic (6.97e-2)" "unprognostic (8.36e-2)" "unprognostic (9.82e-2)" "unprognostic (1.50e-1)" "unprognostic (2.19e-2)" GLI3 "ACLS, GCPS, PAP-A, PAPA, PAPA1, PAPB, PHS, PPDIV" ENSG00000106571 "GLI family zinc finger 3" P10071 7 41960949-42264100 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 474.3;Cytotrophoblasts: 176.6;Fibro-adipogenic progenitors: 436.1;Medullary thymic epithelial cells: 204.0;Mesothelial cells: 315.9;Pituicytes/FSCs: 273.6;Syncytiotrophoblasts: 332.2" "Cell type enhanced" "Detected in many" "astrocyte: 487.7;ependymal cell: 145.9;fibroblast: 171.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Spleen - Fibroblasts_1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA005534 Approved Approved Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 75: Ovary - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 54: Non-specific - Transcription" "Cluster 108: Fibroblasts - ECM organization" 17 Nucleoplasm "Nucleoli, Vesicles" "HPA005534: " "unprognostic (1.93e-1)" "unprognostic (4.51e-2)" "unprognostic (4.63e-1)" "unprognostic (1.47e-2)" "unprognostic (3.50e-2)" "unprognostic (1.73e-1)" "unprognostic (3.37e-1)" "potential prognostic unfavorable (2.64e-4)" "unprognostic (4.82e-2)" "unprognostic (7.22e-2)" "unprognostic (1.77e-1)" "unprognostic (3.22e-1)" "unprognostic (6.78e-2)" "unprognostic (5.74e-2)" "unprognostic (1.64e-1)" "unprognostic (2.64e-1)" "unprognostic (8.13e-2)" "unprognostic (1.50e-2)" "unprognostic (2.63e-1)" "unprognostic (4.49e-2)" "unprognostic (1.15e-1)" "unprognostic (4.21e-2)" "unprognostic (2.81e-2)" "unprognostic (1.80e-1)" "unprognostic (1.11e-2)" "unprognostic (1.24e-1)" "unprognostic (1.89e-3)" "unprognostic (1.92e-1)" GLI4 "HKR4, ZNF928" ENSG00000250571 "GLI family zinc finger 4" P10075 8 143267433-143276931 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023131 Uncertain Approved "Nucleoplasm,Cytokinetic bridge" Yes No "Cluster 14: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 3 "Nucleoplasm, Cytokinetic bridge" "HPA023131: " "unprognostic (5.70e-2)" "unprognostic (4.56e-2)" "unprognostic (2.39e-1)" "unprognostic (2.39e-2)" "unprognostic (1.33e-2)" "unprognostic (1.80e-1)" "unprognostic (1.13e-1)" "unprognostic (3.68e-2)" "unprognostic (5.20e-2)" "unprognostic (1.32e-2)" "unprognostic (1.43e-3)" "unprognostic (1.46e-1)" "unprognostic (4.20e-1)" "unprognostic (1.30e-2)" "unprognostic (2.26e-1)" "unprognostic (5.49e-2)" "unprognostic (3.01e-2)" "unprognostic (1.93e-1)" "unprognostic (2.44e-2)" "unprognostic (1.61e-1)" "unprognostic (9.78e-2)" "unprognostic (3.52e-2)" "unprognostic (2.18e-2)" "unprognostic (7.99e-2)" "unprognostic (3.30e-2)" "unprognostic (1.78e-1)" "unprognostic (3.08e-2)" "unprognostic (2.56e-1)" "unprognostic (2.45e-1)" "unprognostic (8.30e-3)" "unprognostic (1.59e-2)" GLIPR1 "GliPR, RTVP1" ENSG00000139278 "GLI pathogenesis related 1" P48060 12 75480753-75503863 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 81.2" "Cell type enhanced" "Detected in many" "cDC: 294.5;Decidual stromal cells: 259.4;Epididymal basal cells: 174.2;Extravillous trophoblasts: 657.5;Hematopoietic stem cells: 165.0;Hofbauer cells: 269.5;Kupffer cells: 265.5;Macrophages: 206.0;Monocyte progenitors: 210.4;monocytes: 390.2;Neutrophils: 336.2;pDCs: 167.2;T-cells: 182.6;Thymocytes: 166.8" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 146.3;leukocyte: 85.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA011014, HPA011084" Approved Approved Nucleoplasm,Vesicles "Intracellular and membrane" "No annotated function" NA NA 38000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 7 Vesicles Nucleoplasm "HPA011014: , HPA011084: " "unprognostic (5.54e-3)" "unprognostic (1.47e-2)" "unprognostic (1.07e-1)" "unprognostic (6.80e-2)" "unprognostic (3.16e-1)" "unprognostic (5.21e-1)" "unprognostic (1.43e-1)" "unprognostic (1.30e-1)" "unprognostic (1.41e-1)" "unprognostic (3.51e-1)" "unprognostic (1.03e-1)" "unprognostic (4.84e-2)" "unprognostic (2.62e-3)" "potential prognostic unfavorable (1.34e-4)" "unprognostic (2.58e-1)" "unprognostic (8.73e-2)" "unprognostic (3.05e-3)" "unprognostic (1.87e-1)" "unprognostic (1.56e-2)" "unprognostic (1.10e-2)" "unprognostic (7.84e-2)" "unprognostic (1.73e-1)" "unprognostic (2.52e-1)" "unprognostic (1.03e-1)" "unprognostic (6.19e-3)" "unprognostic (2.92e-1)" "unprognostic (1.16e-1)" "unprognostic (4.20e-3)" "unprognostic (1.06e-2)" "unprognostic (4.73e-2)" "unprognostic (1.21e-1)" GLIPR1L1 MGC26856 ENSG00000173401 "GLIPR1 like 1" Q6UWM5 12 75334670-75370560 "Predicted secreted proteins" Fertilization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 53 "testis: 28.9" "Cell type enhanced" "Detected in many" "Adipocytes: 113.1;Cardiomyocytes: 315.6;Early spermatids: 220.7;Epicardial cells: 68.2;Fibro-adipogenic progenitors: 82.3;Late primary spermatocytes: 503.2;Myonuclei: 67.0" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Low region specificity" "Detected in all" HPA042095 Enhanced "Secreted in male reproductive system" Other NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 25: Non-specific - Transcription" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" "HPA042095: " "unprognostic (1.05e-1)" "unprognostic (9.77e-2)" GLIPR1L2 MGC39497 ENSG00000180481 "GLIPR1 like 2" Q4G1C9 12 75391089-75432688 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "testis: 43.6" "Group enriched" "Detected in many" 9 "Early primary spermatocytes: 153.2;Early spermatids: 196.1;Late primary spermatocytes: 612.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in single" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA039795, HPA039866" Enhanced Approved "Golgi apparatus,Vesicles" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 67: Testis - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 18: Liver cancer - Metabolism" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" "Golgi apparatus" Vesicles "HPA039795: , HPA039866: " "unprognostic (5.11e-2)" "unprognostic (1.52e-1)" "unprognostic (3.86e-1)" "unprognostic (3.03e-2)" "unprognostic (1.38e-1)" "unprognostic (5.61e-2)" "unprognostic (4.05e-2)" "potential prognostic unfavorable (6.17e-5)" "unprognostic (5.87e-3)" "unprognostic (4.04e-2)" "unprognostic (6.27e-2)" "unprognostic (5.33e-3)" "unprognostic (1.79e-1)" "unprognostic (4.71e-2)" "unprognostic (3.26e-1)" "unprognostic (1.75e-1)" "unprognostic (2.77e-2)" "unprognostic (1.92e-2)" "unprognostic (2.03e-2)" "unprognostic (1.00e-1)" "unprognostic (7.37e-3)" "unprognostic (2.03e-1)" "unprognostic (2.01e-1)" "unprognostic (1.50e-1)" "unprognostic (1.11e-1)" "unprognostic (1.22e-1)" GLIPR2 "C9orf19, GAPR-1" ENSG00000122694 "GLI pathogenesis related 2" Q9H4G4 9 36136536-36163913 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 341.9;cDC: 194.0;Hepatic stellate cells: 142.0;Monocyte progenitors: 169.4;monocytes: 284.7;Neutrophil progenitors: 211.0;Neutrophils: 576.4" "Cell type enhanced" "Detected in many" "leukocyte: 69.1;oligodendrocyte: 56.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Fibroblasts, Skeletal muscle - Fibroblasts, Spleen - Neutrophils_2, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029478 Approved Uncertain Vesicles,Microtubules NA NA 13000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" Vesicles Microtubules "HPA029478: " "unprognostic (1.50e-2)" "unprognostic (1.21e-3)" "unprognostic (2.00e-2)" "unprognostic (6.29e-2)" "unprognostic (1.30e-1)" "unprognostic (8.27e-3)" "unprognostic (1.42e-2)" "unprognostic (3.70e-1)" "unprognostic (7.92e-2)" "unprognostic (1.67e-1)" "unprognostic (2.96e-2)" "unprognostic (1.83e-1)" "unprognostic (1.55e-1)" "unprognostic (4.06e-2)" "unprognostic (3.58e-2)" "unprognostic (1.50e-2)" "unprognostic (1.34e-2)" "unprognostic (9.91e-3)" "unprognostic (3.15e-1)" "unprognostic (2.40e-1)" "unprognostic (5.34e-2)" "unprognostic (9.92e-2)" "unprognostic (1.77e-1)" "unprognostic (4.98e-2)" "unprognostic (5.06e-2)" "unprognostic (3.85e-1)" "unprognostic (3.99e-2)" "unprognostic (1.64e-2)" "unprognostic (3.00e-1)" "unprognostic (1.26e-1)" "unprognostic (5.95e-2)" GLIS1 FLJ36155 ENSG00000174332 "GLIS family zinc finger 1" Q8NBF1 1 53506237-53739164 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "prostate: 7.7;seminal vesicle: 7.0" "Cell type enriched" "Detected in many" 4 "Proximal tubule cells: 319.8" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Kidney Renal Clear Cell Carcinoma (TCGA): 6.9;Kidney Renal Papillary Cell Carcinoma (TCGA): 7.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 4.3" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Kidney - Proximal tubular cells, Stomach - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA001409 Uncertain Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 64: Non-specific - Transcription" "Cluster 53: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 88: Proximal tubular cells - Transmembrane transport" 2 Nucleoplasm "Nuclear bodies, Cytosol" "HPA001409: " "unprognostic (1.45e-1)" "unprognostic (1.27e-1)" "unprognostic (6.98e-3)" "unprognostic (2.94e-3)" "unprognostic (2.06e-2)" "unprognostic (2.31e-2)" "unprognostic (6.23e-2)" "unprognostic (1.35e-1)" GLIS2 NPHP7 ENSG00000126603 "GLIS family zinc finger 2" Q9BZE0 16 4314761-4339597 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Ciliopathy, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 8.0;Choroid plexus epithelial cells: 9.9;Distal convoluted tubule cells: 22.6;Loop of henle epithelial cells: 22.3;Oligodendrocyte progenitor cells: 7.2;Papillary tip epithelial cells: 12.0;Podocytes: 9.5;Proximal tubule cells: 35.6;Renal collecting duct intercalated cells: 19.3;Renal collecting duct principal cells: 28.4;Renal connecting tubule cells: 25.2" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Kidney Renal Papillary Cell Carcinoma (TCGA): 33.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Fibroblasts, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062755, HPA065406" Approved "Nucleoplasm,Basal body" NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 44: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 88: Proximal tubular cells - Transmembrane transport" 32 Nucleoplasm "Basal body" "HPA062755: , HPA065406: " "unprognostic (3.69e-3)" "unprognostic (1.78e-1)" "unprognostic (1.99e-1)" "unprognostic (1.08e-2)" "unprognostic (5.48e-2)" "unprognostic (1.32e-1)" "unprognostic (4.76e-2)" "unprognostic (1.74e-1)" "unprognostic (1.04e-1)" "unprognostic (6.00e-3)" "potential prognostic favorable (5.58e-4)" "unprognostic (1.56e-1)" "unprognostic (4.29e-1)" "unprognostic (1.90e-2)" "unprognostic (4.31e-2)" "unprognostic (1.94e-1)" "unprognostic (1.02e-1)" "unprognostic (1.38e-2)" "unprognostic (1.21e-1)" "unprognostic (1.38e-3)" "unprognostic (2.29e-2)" "unprognostic (2.32e-1)" "unprognostic (1.13e-1)" "unprognostic (3.43e-1)" "unprognostic (1.19e-1)" "unprognostic (1.06e-1)" "unprognostic (5.83e-2)" "unprognostic (1.13e-1)" "unprognostic (2.64e-2)" "unprognostic (2.11e-2)" "unprognostic (4.33e-3)" GLIS3 "MGC33662, ZNF515" ENSG00000107249 "GLIS family zinc finger 3" Q8NEA6 9 3824127-4348392 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Congenital hypothyroidism, Diabetes mellitus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 14.0" "Cell type enhanced" "Detected in many" "Astrocytes: 1075.2;Choroid plexus epithelial cells: 1624.0;Endometrial glandular cells: 920.2;Ependymal cells: 1552.5;Pancreatic duct cells: 1414.4;Pituicytes/FSCs: 856.8;Renal collecting duct intercalated cells: 860.4;Renal collecting duct principal cells: 1210.0;Renal connecting tubule cells: 1923.3" "Group enriched" "Detected in all" 5 "astrocyte: 1626.4;Bergmann glia: 824.6;choroid plexus epithelial cell: 1289.9;ependymal cell: 1730.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipose progenitor cells, Heart muscle - Fibroblasts, Minor Salivary Gland - Minor salivary glandular cells, Skin - Endothelial cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA056426 Approved Approved "Nucleoplasm,Golgi apparatus,Primary cilium" NA NA "Cluster 55: Breast - Lactation" "Cluster 39: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 51: Secretory epithelial cells - Mixed function" 5 Nucleoplasm "Golgi apparatus, Primary cilium" "HPA056426: " "unprognostic (2.45e-1)" "unprognostic (4.40e-2)" "unprognostic (4.99e-1)" "unprognostic (5.52e-2)" "unprognostic (3.80e-1)" "unprognostic (1.43e-1)" "unprognostic (2.89e-1)" "unprognostic (5.03e-1)" "unprognostic (1.03e-1)" "unprognostic (2.53e-1)" "potential prognostic favorable (9.12e-5)" "unprognostic (2.53e-2)" "unprognostic (4.53e-2)" "unprognostic (9.40e-3)" "unprognostic (2.01e-2)" "unprognostic (5.18e-2)" "unprognostic (2.21e-3)" "unprognostic (5.02e-2)" "unprognostic (1.70e-1)" "unprognostic (2.15e-1)" "unprognostic (4.47e-2)" "unprognostic (2.73e-2)" "unprognostic (4.31e-2)" "unprognostic (2.78e-1)" "unprognostic (1.19e-2)" "unprognostic (4.02e-2)" "unprognostic (9.22e-3)" "unprognostic (1.10e-1)" "unprognostic (1.85e-1)" "unprognostic (9.69e-3)" GLMN "FAP48, FAP68, FKBPAP, GLML, GVM, VMGLOM" ENSG00000174842 "Glomulin, FKBP associated protein" Q92990 1 92246402-92298987 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 36.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 387.1;Retinal ganglion cells: 173.8;Rod photoreceptor cells: 486.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031446, HPA031448" Approved Approved Nucleoplasm,Cytosol NA NA 6300 "Cluster 24: Non-specific - Transcription" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 31: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 79: Photoreceptor cells - Phototransduction" 43 "Nucleoplasm, Cytosol" "HPA031446: , HPA031448: " "unprognostic (9.90e-2)" "unprognostic (7.10e-2)" "unprognostic (3.12e-1)" "unprognostic (4.85e-1)" "unprognostic (1.20e-3)" "unprognostic (1.87e-3)" "unprognostic (1.19e-1)" "unprognostic (1.46e-2)" "unprognostic (1.26e-1)" "unprognostic (2.30e-1)" "unprognostic (2.98e-1)" "unprognostic (1.23e-1)" "unprognostic (2.93e-1)" "potential prognostic unfavorable (3.51e-7)" "unprognostic (2.16e-3)" "unprognostic (2.96e-2)" "unprognostic (2.80e-1)" "unprognostic (1.94e-2)" "unprognostic (3.13e-2)" "unprognostic (1.87e-1)" "unprognostic (2.29e-1)" "unprognostic (1.53e-1)" "unprognostic (9.89e-3)" "unprognostic (3.74e-2)" "unprognostic (1.53e-2)" "unprognostic (8.72e-2)" "unprognostic (4.83e-3)" "unprognostic (5.10e-2)" "unprognostic (2.71e-1)" "unprognostic (2.66e-2)" "unprognostic (9.24e-3)" GLMP "C1orf85, MGC31963, NCU-G1" ENSG00000198715 "Glycosylated lysosomal membrane protein" Q8WWB7 1 156290089-156295689 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 80.1;Esophageal apical cells: 106.0;Extravillous trophoblasts: 91.9;Hepatocytes: 83.9;Hofbauer cells: 334.9;Kupffer cells: 94.3;Syncytiotrophoblasts: 81.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adrenal gland - Adrenal cortex cells, Breast - Fibroblasts, Lung - Macrophages, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029121 Uncertain NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 28: Liver & Adrenal gland - Secretion" "Cluster 21: Non-specific - Metabolism" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" "HPA029121: " "unprognostic (2.48e-2)" "unprognostic (7.46e-2)" "unprognostic (4.00e-3)" "unprognostic (2.61e-1)" "unprognostic (1.27e-3)" "unprognostic (1.23e-3)" "unprognostic (3.89e-3)" "unprognostic (5.72e-2)" "unprognostic (3.47e-1)" "unprognostic (8.36e-3)" "potential prognostic unfavorable (6.88e-5)" "unprognostic (1.33e-1)" "potential prognostic unfavorable (5.02e-6)" "unprognostic (2.59e-1)" "unprognostic (1.63e-1)" "unprognostic (2.09e-1)" "unprognostic (6.83e-2)" "unprognostic (2.53e-2)" "unprognostic (8.37e-3)" "unprognostic (2.84e-1)" "unprognostic (2.11e-1)" "unprognostic (1.29e-1)" "unprognostic (6.93e-3)" "unprognostic (8.43e-2)" "unprognostic (1.53e-1)" "unprognostic (3.97e-2)" "unprognostic (1.45e-1)" "unprognostic (2.25e-1)" "unprognostic (8.92e-2)" GLO1 GLOD1 ENSG00000124767 "Glyoxalase I" Q04760 6 38675925-38703145 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Lyase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 424.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB040541, CAB040542, HPA059791" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" No No 2000000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 49: HMC-1 - Innate immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 6 "Nucleoplasm, Plasma membrane, Cytosol" "CAB040541: , CAB040542: , HPA059791: " "unprognostic (1.94e-1)" "unprognostic (1.15e-2)" "unprognostic (1.59e-2)" "unprognostic (4.12e-1)" "unprognostic (8.69e-2)" "unprognostic (3.25e-1)" "unprognostic (3.57e-3)" "unprognostic (2.86e-1)" "unprognostic (5.56e-2)" "unprognostic (5.67e-3)" "validated prognostic favorable (1.37e-5)" "validated prognostic favorable (6.28e-4)" "unprognostic (3.19e-2)" "validated prognostic unfavorable (4.65e-4)" "validated prognostic unfavorable (2.84e-5)" "unprognostic (1.94e-1)" "unprognostic (1.15e-1)" "unprognostic (2.54e-2)" "unprognostic (1.29e-1)" "unprognostic (3.41e-3)" "unprognostic (1.16e-1)" "unprognostic (2.47e-2)" "unprognostic (4.38e-1)" "unprognostic (1.08e-1)" "unprognostic (6.00e-3)" "unprognostic (8.08e-2)" "unprognostic (1.06e-1)" "unprognostic (9.13e-3)" "unprognostic (2.10e-1)" "unprognostic (5.86e-2)" "unprognostic (1.29e-1)" GLOD4 "C17orf25, CGI-150, HC71" ENSG00000167699 "Glyoxalase domain containing 4" Q9HC38 17 757097-782294 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "Parietal cells: 809.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells, Skeletal muscle - Fibroblasts, Stomach - Parietal cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "HPA021623, HPA023246, HPA023248" Enhanced Approved Cytosol NA NA 3500000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 2 Cytosol "HPA021623: , HPA023246: , HPA023248: " "unprognostic (1.28e-2)" "unprognostic (9.43e-2)" "unprognostic (1.99e-2)" "unprognostic (4.69e-2)" "unprognostic (3.49e-2)" "unprognostic (3.18e-1)" "unprognostic (2.49e-1)" "unprognostic (1.11e-2)" "unprognostic (2.53e-1)" "unprognostic (2.62e-1)" "validated prognostic favorable (8.19e-11)" "validated prognostic favorable (7.25e-4)" "potential prognostic favorable (2.78e-4)" "unprognostic (2.76e-1)" "unprognostic (1.69e-1)" "unprognostic (3.79e-2)" "unprognostic (4.43e-2)" "unprognostic (2.47e-1)" "unprognostic (1.48e-1)" "unprognostic (2.68e-1)" "unprognostic (4.20e-2)" "unprognostic (2.37e-1)" "unprognostic (3.51e-2)" "unprognostic (8.52e-2)" "unprognostic (2.26e-2)" "unprognostic (2.55e-1)" "unprognostic (1.98e-1)" "unprognostic (3.41e-3)" "unprognostic (2.60e-1)" "unprognostic (1.35e-1)" "unprognostic (1.75e-2)" GLOD5 ENSG00000171433 "Glyoxalase domain containing 5" A6NK44 X 48761747-48773648 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "epididymis: 5.5;intestine: 9.9;kidney: 10.4;liver: 7.6" "Cell type enhanced" "Detected in many" "Breast lactating cells: 73.5;Early primary spermatocytes: 18.5;Enterocytes: 42.9;Epididymal efferent duct absorptive cells: 21.5;Mast cells: 74.6;Megakaryocyte-Erythroid progenitors: 34.5;Platelets: 107.6" "Cell type enhanced" "Detected in some" "ependymal cell: 8.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Breast glandular cells, Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA010667 Enhanced Uncertain Mitochondria NA NA "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 58: Mast cells - Allergic inflammatory responses" Mitochondria "HPA010667: " "unprognostic (1.21e-2)" "unprognostic (1.21e-1)" "unprognostic (1.57e-1)" "unprognostic (5.71e-2)" "unprognostic (4.75e-2)" "potential prognostic favorable (8.85e-7)" "unprognostic (1.49e-3)" "unprognostic (3.13e-2)" "unprognostic (3.54e-2)" "unprognostic (2.98e-2)" "unprognostic (3.88e-3)" "unprognostic (1.57e-1)" "unprognostic (2.50e-1)" "unprognostic (1.76e-1)" "unprognostic (1.11e-1)" "unprognostic (1.93e-2)" "unprognostic (9.76e-2)" "unprognostic (2.30e-1)" "unprognostic (1.76e-2)" "unprognostic (4.22e-2)" "unprognostic (4.59e-2)" "unprognostic (3.70e-2)" GLP1R GLP-1R ENSG00000112164 "Glucagon like peptide 1 receptor" P43220 6 39048781-39091303 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 2.6;pancreas: 8.6" "Cell type enhanced" "Detected in some" "Lacrimal acinar cells: 19.0;Neuroendocrine cells: 8.0;Other brain neurons: 10.8;Pancreatic acinar cells: 15.5;Pancreatic islet cells: 23.3;Proximal tubule cells: 5.7;Salivary acinar cells: 4.8;Tuft cells: 46.1" "Cell type enhanced" "Detected in some" "splatter: 5.3;vascular associated smooth muscle cell: 3.0" "Cancer enhanced" "Detected in some" "Pancreatic Adenocarcinoma (TCGA): 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Leukemia: 1.9" "Heart muscle - Cardiomyocytes, Skin - Eccrine sweat gland cells, Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in many" 4 "basal ganglia: 20.7" "Low region specificity" "Detected in some" CAB080541 Approved "Nuclear bodies,Golgi apparatus,Plasma membrane,Centrosome" NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 59: Leukemia - T-cell receptor" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 52 "Nuclear bodies, Plasma membrane" "Golgi apparatus, Centrosome" "CAB080541: " "unprognostic (7.38e-2)" "unprognostic (3.11e-1)" "unprognostic (2.28e-2)" GLP2R ENSG00000065325 "Glucagon like peptide 2 receptor" O95838 17 9822206-9892099 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 11.4;intestine: 13.4;urinary bladder: 12.1" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 20.7;Fibro-adipogenic progenitors: 13.1;Fibroblasts: 7.6;Hepatic stellate cells: 12.9;Leydig cells: 8.8;Rod photoreceptor cells: 59.0" "Cell type enhanced" "Detected in some" "amygdala excitatory: 12.2;upper-layer intratelencephalic: 33.8" "Cancer enhanced" "Detected in single" "Pancreatic Adenocarcinoma (TCGA): 2.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 17.9;liver cancer: 9.1;Rhabdoid: 8.6" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Liver - Hepatic stellate cells, Lung - Fibroblasts_2, Pancreas - Fibroblasts, Stomach - Fibroblasts" "Group enriched" "Detected in some" 5 "cerebral cortex: 2.1;hippocampal formation: 2.4" "Low region specificity" "Detected in all" "CAB022690, HPA049244" Approved Supported "Plasma membrane" NA NA "Cluster 77: Intestine - Digestion" "Cluster 51: Neurons - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 103: Non-specific - Basic cellular processes" "Plasma membrane" "CAB022690: , HPA049244: " "unprognostic (9.87e-2)" "unprognostic (2.87e-1)" "unprognostic (3.49e-3)" "unprognostic (6.02e-2)" GLRA1 STHE ENSG00000145888 "Glycine receptor alpha 1" P23415 5 151822513-151924851 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "retina: 2.3" "Cell type enhanced" "Detected in many" "Adipocytes: 19.4;Adrenal medulla cells: 42.5;Cardiomyocytes: 39.9;Epicardial cells: 15.9;Hepatic stellate cells: 25.8;Myonuclei: 21.4;Other brain neurons: 18.5;Retinal amacrine cells: 30.5;Retinal bipolar cells: 81.9;Retinal ganglion cells: 23.2;Rod photoreceptor cells: 16.7" "Cell type enhanced" "Detected in many" "lower rhombic lip: 33.0;splatter: 41.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adrenal gland - Adrenal medulla cells, Pancreas - Beta cells" "Group enriched" "Detected in many" 5 "hypothalamus: 9.4;midbrain: 15.1;pons and medulla: 26.3" "Low region specificity" "Detected in all" "HPA078885, CAB079042" Supported Approved "Vesicles,Plasma membrane" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 43: Hindbrain - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 2 "Vesicles, Plasma membrane" "CAB079042: , HPA078885: " "unprognostic (4.02e-2)" GLRA2 GLR ENSG00000101958 "Glycine receptor alpha 2" P23416 X 14529298-14731812 "Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.9;intestine: 1.5;retina: 3.0" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 60.2;Brain inhibitory neurons: 58.2;Colonocytes: 42.6;Epicardial cells: 22.7;Gonadotrophs: 24.2;Oligodendrocytes: 21.1;Other brain neurons: 61.7;Retinal amacrine cells: 176.8;Retinal ganglion cells: 69.5;Retinal horizontal cells: 66.1" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Rectum Adenocarcinoma (TCGA): 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pituitary gland - Gonadotropes, Skin - Hair cortex cells, Skin - Inner root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB070422, HPA078885" Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 40: Non-specific - Unknown function" "Cluster 109: Neurons - Neuronal signaling" "Vesicles, Plasma membrane" "CAB070422: , HPA078885: " "unprognostic (1.18e-1)" "unprognostic (1.69e-1)" "unprognostic (2.88e-2)" "unprognostic (1.20e-1)" "unprognostic (2.49e-1)" "unprognostic (9.84e-2)" GLRA3 ENSG00000145451 "Glycine receptor alpha 3" O75311 4 174636920-174829247 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 5.2;breast: 1.9" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 31.9;Brain excitatory neurons: 59.5;Brain inhibitory neurons: 33.8;Breast hormone-responsive cells: 55.4;Early spermatids: 42.0;Gonadotrophs: 63.0;Late spermatids: 30.7;Other brain neurons: 72.9;Pancreatic islet cells: 26.8;Retinal amacrine cells: 116.2;Somatotrophs: 18.5;Thyrotrophs: 31.9" "Cell type enhanced" "Detected in many" "amygdala excitatory: 161.0;upper-layer intratelencephalic: 145.1" "Cancer enriched" "Detected in single" 4 "Breast Invasive Carcinoma (TCGA): 2.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lymphoma: 1.4" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Beta cells, Pituitary gland - Thyrotropes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA078885 Approved "Vesicles,Plasma membrane" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 109: Neurons - Neuronal signaling" 1 "Vesicles, Plasma membrane" "HPA078885: " "unprognostic (1.57e-2)" "unprognostic (2.44e-1)" "unprognostic (4.32e-3)" "unprognostic (1.36e-1)" GLRB ENSG00000109738 "Glycine receptor beta" P48167 4 157076125-157172090 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 41.3;parathyroid gland: 31.1" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 124.2;Brain inhibitory neurons: 132.6;Choroid plexus epithelial cells: 48.0;Corticotrophs: 68.4;Lacrimal acinar cells: 48.0;Lactotrophs: 55.1;Oligodendrocyte progenitor cells: 142.3;Other brain neurons: 86.2;Retinal ganglion cells: 50.2;Somatotrophs: 46.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipocytes (Visceral), Pituitary gland - Corticotropes, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052363 Approved NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 73: Brain - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 72: Neuronal - Signal transduction" "Cluster 109: Neurons - Neuronal signaling" 1 "HPA052363: " "unprognostic (2.02e-1)" "unprognostic (1.35e-1)" "unprognostic (5.02e-2)" "unprognostic (3.32e-2)" "unprognostic (2.87e-1)" "unprognostic (5.34e-2)" "unprognostic (9.99e-2)" "unprognostic (6.21e-2)" "unprognostic (1.94e-2)" "unprognostic (8.44e-2)" "unprognostic (7.01e-2)" "unprognostic (2.54e-3)" "unprognostic (4.04e-1)" "unprognostic (1.69e-1)" "unprognostic (5.70e-2)" "unprognostic (1.49e-1)" "unprognostic (2.37e-1)" "unprognostic (1.12e-1)" "unprognostic (7.39e-2)" "unprognostic (8.79e-2)" "unprognostic (4.24e-2)" "potential prognostic favorable (5.14e-4)" "unprognostic (2.96e-3)" "unprognostic (7.58e-2)" "unprognostic (1.50e-1)" "unprognostic (6.04e-2)" GLRX "GRX, GRX1" ENSG00000173221 Glutaredoxin P35754 5 95751319-95822726 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Electron transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 806.3" "Cell type enhanced" "Detected in many" "Adipocytes: 594.5;Cardiomyocytes: 654.1;Enterocytes: 896.5;Extravillous trophoblasts: 1097.9;Kupffer cells: 428.4;Oocytes: 851.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Minor Salivary Gland - Minor salivary glandular cells, Skin - Macrophages, Spleen - Neutrophils_2, Thyroid gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008634, HPA046431, CAB069419" Approved Supported "Plasma membrane,Cytosol" NA NA 2400000 "Cluster 29: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 89: Adipocytes - Lipid metabolism" 3 "Plasma membrane, Cytosol" "CAB008634: , CAB069419: , HPA046431: " "unprognostic (1.64e-1)" "unprognostic (2.80e-1)" "unprognostic (4.27e-2)" "unprognostic (3.19e-2)" "unprognostic (5.72e-2)" "unprognostic (1.48e-2)" "unprognostic (7.38e-3)" "unprognostic (1.84e-2)" "unprognostic (7.83e-2)" "unprognostic (3.28e-1)" "potential prognostic favorable (9.76e-8)" "unprognostic (5.78e-2)" "unprognostic (5.55e-2)" "unprognostic (5.03e-3)" "unprognostic (7.10e-2)" "unprognostic (5.33e-3)" "unprognostic (2.13e-1)" "unprognostic (2.65e-2)" "unprognostic (1.71e-1)" "unprognostic (2.09e-2)" "unprognostic (1.12e-1)" "unprognostic (3.18e-1)" "unprognostic (1.81e-1)" "unprognostic (5.38e-2)" "unprognostic (1.09e-1)" "unprognostic (1.66e-1)" "unprognostic (7.22e-2)" "unprognostic (2.83e-1)" "unprognostic (5.64e-2)" "unprognostic (1.02e-1)" "unprognostic (5.30e-3)" GLRX2 "bA101E13.1, GRX2" ENSG00000023572 "Glutaredoxin 2" Q9NS18 1 193090866-193106114 "Metabolic proteins, Predicted intracellular proteins" "Electron transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 14 "Early spermatids: 1047.1;Late spermatids: 2933.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "HPA023087, HPA057224" Supported Supported Nucleoplasm,Vesicles NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 35: Non-specific - Mixed function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 2 Nucleoplasm Vesicles "HPA023087: , HPA057224: " "unprognostic (5.39e-2)" "unprognostic (3.01e-2)" "unprognostic (2.73e-1)" "unprognostic (1.77e-2)" "unprognostic (8.00e-2)" "unprognostic (9.79e-2)" "unprognostic (1.52e-2)" "unprognostic (2.46e-1)" "unprognostic (2.09e-2)" "unprognostic (2.49e-2)" "unprognostic (2.55e-2)" "potential prognostic unfavorable (8.26e-7)" "unprognostic (5.48e-2)" "potential prognostic unfavorable (6.77e-4)" "unprognostic (8.52e-2)" "potential prognostic unfavorable (2.11e-5)" "unprognostic (6.17e-3)" "unprognostic (7.07e-2)" "unprognostic (4.61e-2)" "unprognostic (7.44e-3)" "unprognostic (8.74e-2)" "unprognostic (1.07e-2)" "unprognostic (1.46e-1)" "unprognostic (3.00e-1)" "unprognostic (2.63e-1)" "unprognostic (1.38e-2)" "unprognostic (1.27e-1)" "unprognostic (5.87e-3)" "unprognostic (1.68e-1)" "unprognostic (1.21e-1)" "unprognostic (1.01e-2)" GLRX3 "bA500G10.4, GLRX4, GRX3, GRX4, PICOT, TXNL2" ENSG00000108010 "Glutaredoxin 3" O76003 10 130136391-130184521 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal suprabasal cells: 319.3;Late primary spermatocytes: 367.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028941 Approved NA NA 670000 "Cluster 33: Non-specific - ATP binding" "Cluster 39: Testis - Nuclear processes" "Cluster 45: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 17: Non-specific - RNA processing" 118 "HPA028941: " "unprognostic (2.01e-2)" "unprognostic (3.28e-3)" "unprognostic (3.43e-2)" "unprognostic (1.24e-2)" "unprognostic (6.78e-2)" "unprognostic (1.77e-1)" "unprognostic (9.33e-2)" "unprognostic (1.70e-2)" "potential prognostic unfavorable (6.05e-4)" "potential prognostic unfavorable (9.86e-4)" "potential prognostic favorable (2.53e-4)" "unprognostic (4.54e-2)" "unprognostic (2.01e-2)" "potential prognostic unfavorable (3.20e-8)" "unprognostic (3.52e-3)" "potential prognostic unfavorable (9.17e-4)" "unprognostic (4.86e-2)" "unprognostic (6.41e-2)" "unprognostic (6.59e-2)" "unprognostic (1.80e-1)" "unprognostic (1.93e-3)" "potential prognostic unfavorable (8.19e-4)" "unprognostic (9.30e-3)" "unprognostic (1.24e-3)" "unprognostic (1.26e-1)" "unprognostic (1.77e-3)" "unprognostic (9.60e-2)" "unprognostic (3.12e-2)" "unprognostic (1.87e-1)" "unprognostic (2.75e-1)" "unprognostic (2.76e-1)" GLRX5 "C14orf87, GRX5, PR01238" ENSG00000182512 "Glutaredoxin 5" Q86SX6 14 95533503-95544724 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 304.5;Erythrocyte progenitors: 449.9;Erythrocytes: 779.1;Late primary spermatocytes: 266.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Minor Salivary Gland - Endothelial cells, Skin - Sebaceous gland cells, Spleen - Erythrocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042465, HPA063716" Approved Supported Mitochondria NA NA 6400 "Cluster 30: Non-specific - DNA binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 9 Mitochondria "HPA042465: , HPA063716: " "unprognostic (8.09e-2)" "unprognostic (1.06e-1)" "unprognostic (2.02e-2)" "unprognostic (3.88e-1)" "unprognostic (2.76e-2)" "unprognostic (6.89e-2)" "unprognostic (2.61e-1)" "unprognostic (1.80e-1)" "unprognostic (5.62e-3)" "unprognostic (5.35e-3)" "potential prognostic favorable (8.73e-7)" "unprognostic (2.99e-2)" "unprognostic (4.11e-3)" "unprognostic (6.78e-2)" "unprognostic (1.89e-2)" "unprognostic (1.37e-2)" "unprognostic (1.06e-2)" "unprognostic (1.76e-1)" "unprognostic (1.30e-2)" "unprognostic (1.31e-2)" "unprognostic (3.16e-2)" "unprognostic (1.63e-1)" "unprognostic (2.84e-1)" "unprognostic (6.00e-2)" "unprognostic (4.90e-2)" "unprognostic (5.06e-2)" "unprognostic (1.38e-1)" "unprognostic (3.87e-2)" "unprognostic (6.88e-2)" "unprognostic (1.38e-1)" "unprognostic (1.25e-1)" GLS "GAC, GAM, GLS1, KGA, KIAA0838" ENSG00000115419 Glutaminase O94925 2 190880821-190965552 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Cataract, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 144.3" "Cell type enhanced" "Detected in many" "Podocytes: 820.8;Renal collecting duct principal cells: 812.4;Renal connecting tubule cells: 846.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney cancer: 363.0" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036223 Enhanced Supported Mitochondria No No 18000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 72: Kidney - Transmembrane transport" "Cluster 24: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 20: Non-specific - Transcription regulation" 21 Mitochondria "HPA036223: " "unprognostic (2.38e-2)" "unprognostic (4.18e-2)" "unprognostic (1.44e-1)" "unprognostic (9.57e-3)" "unprognostic (2.12e-1)" "unprognostic (3.31e-1)" "unprognostic (3.09e-1)" "unprognostic (5.24e-2)" "unprognostic (1.27e-2)" "unprognostic (1.48e-1)" "potential prognostic favorable (4.04e-5)" "unprognostic (5.99e-2)" "unprognostic (1.40e-3)" "unprognostic (8.66e-3)" "unprognostic (1.69e-1)" "unprognostic (7.42e-2)" "unprognostic (8.40e-2)" "unprognostic (1.75e-1)" "unprognostic (3.37e-2)" "unprognostic (5.11e-2)" "unprognostic (7.02e-2)" "unprognostic (2.85e-1)" "unprognostic (1.94e-3)" "unprognostic (2.56e-2)" "unprognostic (3.84e-2)" "unprognostic (6.16e-3)" "unprognostic (1.57e-1)" "unprognostic (1.17e-1)" "unprognostic (1.58e-1)" "unprognostic (7.90e-2)" "unprognostic (3.88e-3)" GLS2 "GA, GLS, hLGA, LGA" ENSG00000135423 "Glutaminase 2" Q9UI32 12 56470944-56488414 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 191.6" "Group enriched" "Detected in some" 4 "Distal convoluted tubule cells: 6.4;Hepatocytes: 2.0;Loop of henle epithelial cells: 7.0;Papillary tip epithelial cells: 4.7;Podocytes: 7.5;Proximal tubule cells: 3.1;Renal collecting duct intercalated cells: 5.1;Renal collecting duct principal cells: 7.7;Renal connecting tubule cells: 5.3" "Low cell type specificity" "Detected in some" "Cancer enriched" "Detected in many" 5 "Liver Hepatocellular Carcinoma (TCGA): 24.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Lineage enhanced" "Detected in single" "T-cells: 2.2" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Prostate - Prostate basal glandular cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038608 Uncertain NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 70: DU4475 - Unknown function" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 6 "HPA038608: " "unprognostic (7.15e-2)" "unprognostic (1.33e-1)" "unprognostic (1.05e-2)" "unprognostic (7.18e-3)" "unprognostic (2.08e-1)" "unprognostic (1.42e-1)" "unprognostic (2.39e-1)" "unprognostic (7.43e-2)" "unprognostic (1.13e-1)" "validated prognostic favorable (5.09e-6)" "validated prognostic favorable (7.78e-6)" "unprognostic (1.98e-1)" "unprognostic (4.05e-3)" "unprognostic (1.25e-2)" "unprognostic (2.08e-3)" "unprognostic (8.94e-2)" "unprognostic (3.69e-3)" "unprognostic (1.87e-3)" "unprognostic (1.32e-1)" "unprognostic (2.00e-1)" "unprognostic (4.20e-2)" "unprognostic (4.54e-2)" "unprognostic (7.58e-2)" "unprognostic (4.74e-2)" "unprognostic (2.26e-2)" "unprognostic (1.50e-2)" "unprognostic (2.79e-2)" "unprognostic (1.25e-1)" "unprognostic (2.97e-1)" GLT1D1 FLJ31978 ENSG00000151948 "Glycosyltransferase 1 domain containing 1" Q96MS3 12 128853427-128984968 "Predicted intracellular proteins, Predicted secreted proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 26.5;choroid plexus: 20.0;liver: 25.6" "Group enriched" "Detected in many" 9 "Neutrophil progenitors: 680.3;Neutrophils: 2708.0" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Liver Hepatocellular Carcinoma (TCGA): 9.1;Testicular Germ Cell Tumor (TCGA): 4.5;Thyroid Carcinoma (TCGA): 7.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "neutrophil: 36.5" "Lineage enriched" "Detected in many" 6 "granulocytes: 36.5" "Cancer enhanced" "Detected in some" "Leukemia: 3.3" "Adipose visceral - Neutrophils, Colon - Colon enteroendocrine cells, Lung - Neutrophils_2, Spleen - Neutrophils_2, Stomach - Neutrophils, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039051, HPA039052" Enhanced Cytosol "Secreted to blood" Enzyme NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 23: Choroid plexus - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 24: Neutrophils - Innate immunity signal integration" Cytosol "HPA039051: , HPA039052: " "unprognostic (2.04e-3)" "unprognostic (7.87e-3)" "unprognostic (2.33e-1)" "unprognostic (1.47e-1)" "unprognostic (5.36e-2)" "unprognostic (4.59e-2)" "unprognostic (5.32e-2)" "unprognostic (2.33e-1)" "unprognostic (2.01e-3)" GLT6D1 GLTDC1 ENSG00000204007 "Glycosyltransferase 6 domain containing 1" Q7Z4J2 9 135623648-135639540 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 28 "testis: 4.4" "Cell type enhanced" "Detected in some" "Early spermatids: 45.0;Endometrial glandular cells: 9.4;Late primary spermatocytes: 6.9;Late spermatids: 15.2" "Cell type enhanced" "Detected in single" "LAMP5-LHX6 and Chandelier: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA023424 Uncertain "Intracellular and membrane" Enzyme NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 51: Secretory epithelial cells - Mixed function" "HPA023424: " GLT8D1 "AD-017, FLJ14611" ENSG00000016864 "Glycosyltransferase 8 domain containing 1" Q68CQ7 3 52694486-52706032 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 228.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008808, HPA010588" Approved Approved "Golgi apparatus,Centrosome" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 75: Ovary - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 108: Fibroblasts - ECM organization" 28 "Golgi apparatus" Centrosome "HPA008808: , HPA010588: " "unprognostic (3.85e-2)" "unprognostic (1.39e-1)" "unprognostic (2.33e-1)" "unprognostic (5.44e-2)" "unprognostic (1.56e-1)" "unprognostic (7.03e-2)" "unprognostic (4.80e-2)" "unprognostic (3.32e-3)" "unprognostic (5.59e-2)" "unprognostic (1.13e-2)" "unprognostic (3.04e-2)" "unprognostic (1.42e-1)" "unprognostic (1.65e-1)" "unprognostic (1.28e-1)" "unprognostic (7.37e-2)" "unprognostic (1.76e-1)" "unprognostic (5.47e-3)" "unprognostic (2.22e-1)" "unprognostic (2.18e-1)" "unprognostic (1.46e-1)" "unprognostic (1.38e-1)" "unprognostic (1.38e-1)" "unprognostic (9.27e-2)" "unprognostic (5.39e-2)" "unprognostic (7.89e-2)" "unprognostic (1.48e-1)" "unprognostic (2.25e-1)" "unprognostic (1.05e-3)" "unprognostic (2.02e-1)" "unprognostic (2.34e-2)" "unprognostic (1.77e-1)" GLT8D2 FLJ31494 ENSG00000120820 "Glycosyltransferase 8 domain containing 2" Q9H1C3 12 103988987-104064183 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 42.5;Breast myoepithelial cells: 77.5;Early spermatids: 38.7;Fibro-adipogenic progenitors: 72.7;Fibroblasts: 69.5;Late primary spermatocytes: 37.6;Leydig cells: 98.0;Lymphatic endothelial cells: 40.4;Mesothelial cells: 55.5;Ovarian stromal cells: 93.6;Peritubular myoid cells: 82.9;Somatotrophs: 45.5;Vascular smooth muscle cells: 40.5" "Cell type enhanced" "Detected in many" "LAMP5-LHX6 and Chandelier: 86.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Minor Salivary Gland - Fibroblasts, Pancreas - Fibroblasts, Pituitary gland - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA012740, HPA026904, HPA070791" Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 94: Gonadal somatic cells - Mixed function" "Golgi apparatus, Vesicles" "HPA012740: , HPA026904: , HPA070791: " "unprognostic (2.77e-2)" "unprognostic (4.20e-1)" "unprognostic (1.30e-1)" "unprognostic (3.62e-2)" "unprognostic (2.19e-2)" "unprognostic (2.01e-1)" "unprognostic (2.13e-2)" "unprognostic (5.33e-3)" "unprognostic (1.36e-1)" "unprognostic (2.09e-2)" "unprognostic (1.06e-1)" "unprognostic (2.29e-3)" "potential prognostic unfavorable (1.46e-4)" "unprognostic (2.74e-2)" "unprognostic (4.09e-2)" "unprognostic (3.80e-1)" "unprognostic (6.01e-2)" "unprognostic (3.18e-1)" "unprognostic (4.91e-2)" "unprognostic (7.55e-3)" "unprognostic (1.26e-3)" "unprognostic (5.64e-2)" "unprognostic (3.18e-1)" "unprognostic (9.86e-2)" "unprognostic (6.39e-2)" "unprognostic (8.53e-3)" "unprognostic (3.19e-1)" "potential prognostic unfavorable (3.74e-4)" "unprognostic (3.39e-2)" "unprognostic (6.25e-3)" "unprognostic (1.39e-1)" GLTP ENSG00000139433 "Glycolipid transfer protein" Q9NZD2 12 109850945-109880541 "Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 314.7;skin 1: 257.2" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 3041.5;Esophageal suprabasal cells: 1065.1;Suprabasal keratinocytes: 637.0" "Cell type enhanced" "Detected in all" "oligodendrocyte: 229.8" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 319.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary gland basal cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056461, HPA065503" Approved Supported Cytosol NA NA 21000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 30: White matter - Myelination" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 3 Cytosol "HPA056461: , HPA065503: " "unprognostic (8.45e-3)" "unprognostic (5.01e-3)" "unprognostic (3.25e-2)" "unprognostic (1.80e-1)" "unprognostic (3.90e-2)" "unprognostic (1.57e-1)" "unprognostic (9.01e-2)" "unprognostic (1.69e-1)" "unprognostic (5.97e-2)" "unprognostic (8.29e-3)" "potential prognostic favorable (7.47e-4)" "unprognostic (3.25e-3)" "unprognostic (3.15e-2)" "potential prognostic unfavorable (8.13e-5)" "unprognostic (2.14e-3)" "unprognostic (2.35e-1)" "unprognostic (3.12e-2)" "unprognostic (3.60e-2)" "unprognostic (4.35e-3)" "unprognostic (1.31e-2)" "unprognostic (4.18e-3)" "unprognostic (1.80e-1)" "unprognostic (7.13e-2)" "unprognostic (1.78e-1)" "unprognostic (2.23e-1)" "unprognostic (3.72e-2)" "unprognostic (6.93e-2)" "unprognostic (1.16e-1)" "unprognostic (2.18e-1)" "potential prognostic favorable (2.18e-4)" "potential prognostic favorable (3.55e-4)" GLTPD2 ENSG00000182327 "Glycolipid transfer protein domain containing 2" A6NH11 17 4788964-4790589 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 75.3" "Group enriched" "Detected in some" 6 "Enterocytes: 55.5;Hepatocytes: 168.5" "Cell type enhanced" "Detected in some" "hippocampal CA4: 1.0;lower rhombic lip: 1.1" "Cancer enriched" "Detected in many" 5 "Liver Hepatocellular Carcinoma (TCGA): 35.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 17.5" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA058295, HPA065267" Uncertain Supported Nucleoplasm,Vesicles "Secreted - unknown location" "No annotated function" NA NA 53000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 1: Neurons - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" Vesicles Nucleoplasm "HPA058295: , HPA065267: " "unprognostic (2.19e-1)" "unprognostic (1.62e-1)" "unprognostic (1.05e-1)" "unprognostic (1.01e-1)" "unprognostic (9.41e-2)" "unprognostic (1.45e-1)" "unprognostic (2.51e-1)" "potential prognostic favorable (2.12e-4)" "potential prognostic favorable (6.99e-6)" "unprognostic (9.27e-3)" "unprognostic (2.18e-1)" "unprognostic (1.66e-1)" "unprognostic (9.50e-2)" "unprognostic (9.58e-3)" "potential prognostic favorable (1.70e-4)" "unprognostic (5.95e-2)" "unprognostic (4.18e-2)" "unprognostic (3.19e-1)" "unprognostic (1.25e-1)" GLUD1 "GDH, GDH1, GLUD, hGDH1" ENSG00000148672 "Glutamate dehydrogenase 1" P00367 10 87050202-87094843 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "kidney: 265.0;liver: 860.3" "Cell type enhanced" "Detected in all" "Astrocytes: 574.1;Hepatocytes: 529.1;Respiratory basal cells: 572.5;Respiratory deuterosomal cells: 546.3;Respiratory secretory cells: 497.2" "Cell type enhanced" "Detected in all" "astrocyte: 607.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells" "HPA042492, HPA044839, HPA061369" Approved Supported Mitochondria NA NA 8100000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 28: Astrocytes - Homeostasis & neuron support" 47 Mitochondria "HPA042492: , HPA044839: , HPA061369: " "unprognostic (1.53e-2)" "unprognostic (3.70e-2)" "unprognostic (1.55e-2)" "unprognostic (1.61e-1)" "unprognostic (3.15e-1)" "unprognostic (9.32e-2)" "unprognostic (7.94e-3)" "unprognostic (4.24e-3)" "unprognostic (4.46e-2)" "unprognostic (1.66e-1)" "potential prognostic favorable (1.27e-9)" "unprognostic (2.46e-2)" "unprognostic (6.92e-3)" "unprognostic (2.75e-2)" "unprognostic (1.84e-1)" "unprognostic (1.06e-1)" "unprognostic (2.87e-2)" "unprognostic (3.49e-2)" "unprognostic (1.61e-2)" "unprognostic (7.94e-3)" "unprognostic (9.48e-2)" "potential prognostic unfavorable (4.79e-4)" "unprognostic (1.67e-1)" "unprognostic (6.53e-2)" "unprognostic (9.83e-2)" "unprognostic (1.23e-1)" "unprognostic (4.05e-1)" "unprognostic (4.30e-1)" "unprognostic (5.69e-2)" "unprognostic (7.46e-2)" "unprognostic (9.46e-3)" GLUD2 GLUDP1 ENSG00000182890 "Glutamate dehydrogenase 2" P49448 X 121047610-121050094 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "liver: 3.7;testis: 14.8" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 1.2;Distal convoluted tubule cells: 1.2;Loop of henle epithelial cells: 1.6;Oligodendrocyte progenitor cells: 1.4;Podocytes: 1.0;Proximal tubule cells: 2.9;Renal collecting duct intercalated cells: 2.0" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Liver Hepatocellular Carcinoma (TCGA): 2.4;Skin Cutaneous Melanoma (TCGA): 2.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 3.7" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Liver - Hepatocytes, Testis - Sertoli cells" "HPA042492, HPA044839, HPA061369" Uncertain Supported Mitochondria NA NA "Cluster 67: Testis - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 105: Non-specific - Mixed function" 4 Mitochondria "HPA042492: , HPA044839: , HPA061369: " "unprognostic (5.63e-3)" "unprognostic (1.02e-2)" "potential prognostic favorable (1.24e-7)" "unprognostic (1.05e-1)" "unprognostic (1.85e-3)" "unprognostic (2.79e-3)" "unprognostic (3.50e-2)" "unprognostic (2.12e-1)" "unprognostic (3.81e-2)" GLUL GLNS ENSG00000135821 "Glutamate-ammonia ligase" P15104 1 182378098-182392206 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Angiogenesis "Ligase, Transferase" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 1348.7" "Group enriched" "Detected in all" 4 "Late spermatids: 15525.6;Müller glia: 5656.4;Parietal cells: 4469.2" "Cell type enhanced" "Detected in all" "astrocyte: 466.7;Bergmann glia: 673.0;oligodendrocyte: 416.2" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 839.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 657.9" "Lineage enriched" "Detected in all" 4 "granulocytes: 657.9" "Low cancer specificity" "Detected in all" "Skin - Macrophages, Spleen - Macrophages, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007316, HPA007571, CAB008636" Approved Approved "Plasma membrane,Mitochondria,Cytosol,Connecting piece" NA NA 120000 "Cluster 35: Neutrophils - Protein binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 11: Muller glia cells - Retinal homeostasis" 49 "Mitochondria, Cytosol" "Plasma membrane, Connecting piece" "CAB008636: , HPA007316: , HPA007571: " "unprognostic (3.83e-3)" "unprognostic (1.85e-3)" "unprognostic (6.24e-2)" "potential prognostic favorable (9.17e-5)" "unprognostic (2.85e-1)" "unprognostic (4.73e-2)" "unprognostic (8.27e-2)" "unprognostic (1.86e-1)" "unprognostic (3.76e-2)" "unprognostic (9.17e-2)" "unprognostic (2.65e-2)" "unprognostic (2.41e-1)" "unprognostic (3.64e-2)" "unprognostic (8.89e-2)" "unprognostic (5.06e-2)" "unprognostic (2.60e-1)" "unprognostic (4.64e-3)" "unprognostic (2.89e-1)" "unprognostic (4.50e-1)" "unprognostic (5.51e-2)" "unprognostic (1.13e-1)" "unprognostic (8.13e-2)" "unprognostic (3.42e-1)" "unprognostic (7.75e-2)" "unprognostic (3.56e-2)" "unprognostic (5.49e-2)" "unprognostic (8.31e-2)" "unprognostic (1.30e-2)" "unprognostic (1.70e-1)" "unprognostic (4.59e-2)" "unprognostic (4.86e-1)" GLYAT "ACGNAT, GAT" ENSG00000149124 Glycine-N-acyltransferase Q6IB77 11 58640426-58731974 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Detoxification "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "kidney: 532.9;liver: 651.9" "Cell type enhanced" "Detected in some" "Adipocytes: 218.7;Epididymal efferent duct absorptive cells: 142.1;Hepatocytes: 568.8;Proximal tubule cells: 460.3" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in some" 160 "Kidney Renal Clear Cell Carcinoma (TCGA): 80.6;Kidney Renal Papillary Cell Carcinoma (TCGA): 153.7;Liver Hepatocellular Carcinoma (TCGA): 76.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Adipocytes (Skin), Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA040251, HPA044094" Enhanced NA NA 10000 "Cluster 16: Liver & Kidney - Metabolism" "Cluster 69: Skin cancer - ECM organization" "Cluster 88: Proximal tubular cells - Transmembrane transport" 2 "HPA040251: , HPA044094: " "unprognostic (5.67e-2)" "potential prognostic favorable (3.43e-9)" "unprognostic (4.43e-3)" "potential prognostic favorable (1.94e-6)" "unprognostic (3.32e-3)" "potential prognostic favorable (2.42e-6)" GLYATL1 "FLJ34646, MGC15397" ENSG00000166840 "Glycine-N-acyltransferase like 1" Q969I3 11 58905398-59043527 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 30 "kidney: 130.7;liver: 508.1" "Group enriched" "Detected in many" 6 "Hepatocytes: 313.7;Proximal tubule cells: 110.7" "Cell type enhanced" "Detected in many" "hippocampal CA1-3: 8.8" "Group enriched" "Detected in many" 6 "Kidney Renal Clear Cell Carcinoma (TCGA): 33.1;Kidney Renal Papillary Cell Carcinoma (TCGA): 23.2;Liver Hepatocellular Carcinoma (TCGA): 48.0;Prostate Adenocarcinoma (TCGA): 52.3" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 19 "prostate cancer: 68.5" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells" HPA039501 Supported Uncertain "Golgi apparatus,Cytosol" NA NA "Cluster 16: Liver & Kidney - Metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 88: Proximal tubular cells - Transmembrane transport" 4 "Golgi apparatus" Cytosol "HPA039501: " "unprognostic (2.27e-2)" "unprognostic (8.36e-2)" "unprognostic (1.23e-2)" "unprognostic (1.19e-1)" "unprognostic (3.76e-2)" "potential prognostic favorable (1.12e-10)" "unprognostic (3.12e-3)" "unprognostic (7.16e-3)" "validated prognostic favorable (7.48e-5)" "validated prognostic favorable (1.24e-6)" "unprognostic (5.44e-1)" "potential prognostic favorable (1.50e-5)" "unprognostic (1.67e-1)" "unprognostic (2.23e-1)" GLYATL1B GLYATL1P3 ENSG00000255151 "Glycine-N-acyltransferase like 1B" A0A0U1RQE8 11 59086307-59094786 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 7 "breast: 6.8;lymphoid tissue: 2.6" "Cell type enriched" "Detected in single" 6 "B-cells: 1.9" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Prostate Adenocarcinoma (TCGA): 1.6" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.5" "Lineage enriched" "Detected in single" 15 "B-cells: 1.5" "Group enriched" "Detected in some" 5 "lymphoma: 4.9;Myeloma: 1.4;prostate cancer: 1.8" "Prostate - Prostate glandular cells, Skin - Sebaceous gland cells" HPA039501 Uncertain Uncertain "Golgi apparatus,Cytosol" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 55: Breast - Lactation" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" "Golgi apparatus" Cytosol "HPA039501: " "unprognostic (1.78e-1)" "unprognostic (1.96e-1)" GLYATL2 "BXMAS2-10, MGC24009" ENSG00000156689 "Glycine-N-acyltransferase like 2" Q8WU03 11 58834065-58904215 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 11.2;cervix: 18.7;salivary gland: 33.6" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 21.3;Brain inhibitory neurons: 18.3;Breast lactating cells: 20.3;Breast myoepithelial cells: 42.2;Breast secretory cells: 78.2;Endometrial secretory cells: 53.5;Fibro-adipogenic progenitors: 29.2;Oligodendrocyte progenitor cells: 54.2;Retinal amacrine cells: 22.6;Retinal ganglion cells: 50.2;Submucosal glandular cells: 59.8" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 28.5;Uterine Corpus Endometrial Carcinoma (TCGA): 15.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "breast cancer: 15.2" "Thyroid gland - Fibroblasts" "Not detected" "Not detected" "HPA060292, HPA065454" Uncertain Approved Mitochondria NA NA "Cluster 82: Salivary gland - Secretion" "Cluster 22: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 109: Neurons - Neuronal signaling" Mitochondria "HPA060292: , HPA065454: " "unprognostic (2.92e-2)" "unprognostic (3.58e-2)" "unprognostic (3.09e-2)" "unprognostic (9.44e-2)" "unprognostic (1.65e-3)" "unprognostic (1.02e-1)" "unprognostic (1.01e-2)" "unprognostic (2.76e-1)" "unprognostic (1.02e-1)" "unprognostic (1.12e-2)" "unprognostic (1.18e-3)" "potential prognostic favorable (9.72e-4)" "unprognostic (2.88e-2)" "unprognostic (1.87e-1)" "unprognostic (1.32e-2)" "unprognostic (1.72e-1)" "unprognostic (2.64e-1)" GLYATL3 "bA28H17.2, C6orf140" ENSG00000203972 "Glycine-N-acyltransferase like 3" Q5SZD4 6 49499923-49528078 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "liver: 1.1" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 3.0;Endometrial glandular cells: 1.8;Endometrial luminal cells: 3.5;Neuroendocrine cells: 10.3;Pancreatic acinar cells: 4.8;Pancreatic islet cells: 1.5;Thymocytes: 1.7" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 2.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 1.8;lung cancer: 2.4;prostate cancer: 1.8" "Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA044044 Uncertain NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" "HPA044044: " "unprognostic (1.12e-1)" "unprognostic (3.77e-1)" "unprognostic (1.54e-2)" GLYCTK "HBEBP2, HBEBP4" ENSG00000168237 "Glycerate kinase" Q8IVS8 3 52287089-52295257 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "liver: 138.9" "Group enriched" "Detected in many" 4 "Enterocytes: 100.7;Hepatocytes: 240.3" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 40.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006913 Approved Supported "Golgi apparatus,Cytosol,Rods & Rings" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 6: Non-specific - Immune response" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 49 Cytosol "Golgi apparatus, Rods & Rings" "HPA006913: " "unprognostic (8.82e-3)" "unprognostic (1.87e-1)" "unprognostic (4.60e-3)" "unprognostic (1.73e-3)" "unprognostic (9.39e-2)" "unprognostic (9.60e-2)" "unprognostic (1.02e-1)" "unprognostic (1.79e-1)" "unprognostic (1.23e-2)" "unprognostic (6.89e-2)" "unprognostic (6.33e-2)" "unprognostic (2.27e-1)" "unprognostic (3.37e-3)" "unprognostic (4.24e-2)" "unprognostic (6.61e-2)" "unprognostic (1.70e-1)" "unprognostic (3.68e-2)" "unprognostic (1.14e-1)" "unprognostic (3.44e-2)" "unprognostic (1.18e-1)" "unprognostic (4.85e-2)" "unprognostic (5.16e-2)" "unprognostic (1.39e-1)" "unprognostic (1.70e-1)" "unprognostic (1.60e-2)" "unprognostic (4.07e-2)" "unprognostic (1.70e-1)" "unprognostic (5.43e-2)" "unprognostic (7.17e-2)" "unprognostic (4.76e-2)" "unprognostic (2.05e-1)" GLYR1 "BM045, HIBDL, N-PAC, NP60" ENSG00000140632 "Glyoxylate reductase 1 homolog" Q49A26 16 4803203-4847288 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017022, HPA048226, HPA050136" Enhanced Supported Nucleoplasm,Cytosol NA NA 23000 "Cluster 40: Monocytes - Innate immune response" "Cluster 76: Non-specific - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 19 Nucleoplasm Cytosol "CAB017022: , HPA048226: , HPA050136: " "unprognostic (9.98e-3)" "unprognostic (1.17e-1)" "unprognostic (9.47e-2)" "unprognostic (1.45e-2)" "unprognostic (6.78e-2)" "unprognostic (3.10e-1)" "unprognostic (1.17e-1)" "unprognostic (7.41e-2)" "unprognostic (2.27e-2)" "unprognostic (1.74e-2)" "potential prognostic favorable (2.59e-6)" "unprognostic (1.02e-1)" "unprognostic (1.35e-1)" "unprognostic (1.29e-2)" "unprognostic (7.05e-2)" "unprognostic (3.97e-1)" "unprognostic (1.60e-1)" "unprognostic (3.21e-2)" "unprognostic (1.70e-2)" "unprognostic (1.38e-1)" "unprognostic (7.77e-3)" "unprognostic (2.53e-2)" "unprognostic (1.43e-2)" "unprognostic (8.99e-2)" "unprognostic (3.87e-2)" "unprognostic (8.49e-2)" "unprognostic (9.15e-2)" "unprognostic (2.33e-1)" "unprognostic (2.78e-1)" "unprognostic (1.93e-1)" "unprognostic (8.90e-2)" GM2A "GM2-AP, GM2AP, SAP-3" ENSG00000196743 "Ganglioside GM2 activator" P17900 5 151212150-151270440 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Disease variant, Gangliosidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 107.4;Esophageal apical cells: 124.5;Esophageal suprabasal cells: 115.4;Extravillous trophoblasts: 348.9;Macrophages: 86.6;Migrating cytotrophoblasts: 97.3;Neutrophils: 86.4;Prostatic hillock cells: 92.4" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 40.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "B-cells: 30.9;dendritic cells: 39.4;monocytes: 40.2" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Lung - Macrophages, Skeletal muscle - Fibroblasts, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008063 Enhanced Approved Vesicles,Cytosol "Intracellular and membrane" Enzyme NA NA 8700000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 21 "Vesicles, Cytosol" "HPA008063: " "unprognostic (7.52e-2)" "unprognostic (1.44e-1)" "unprognostic (1.90e-1)" "unprognostic (1.38e-1)" "unprognostic (1.96e-1)" "unprognostic (1.32e-1)" "unprognostic (3.35e-1)" "unprognostic (7.35e-3)" "unprognostic (3.00e-1)" "unprognostic (2.09e-3)" "potential prognostic favorable (2.64e-5)" "unprognostic (6.53e-2)" "unprognostic (8.34e-2)" "potential prognostic unfavorable (1.41e-6)" "unprognostic (1.31e-1)" "unprognostic (1.81e-1)" "unprognostic (2.80e-2)" "unprognostic (1.87e-1)" "unprognostic (1.06e-1)" "unprognostic (1.92e-1)" "unprognostic (6.11e-2)" "unprognostic (8.75e-2)" "unprognostic (3.29e-1)" "unprognostic (1.11e-1)" "unprognostic (1.16e-1)" "unprognostic (5.79e-2)" "unprognostic (4.96e-2)" "unprognostic (8.15e-2)" "unprognostic (7.53e-2)" "unprognostic (1.94e-2)" "unprognostic (1.68e-1)" GMCL1 "BTBD13, FLJ13057, GCL1, SPATA29" ENSG00000087338 "Germ cell-less 1, spermatogenesis associated" Q96IK5 2 69829660-69881384 "Plasma proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 375.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 93.6" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" HPA039579 Approved NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 61: Non-specific - Transcription" "Cluster 23: Choroid plexus - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 68 "HPA039579: " "unprognostic (3.79e-1)" "unprognostic (6.11e-3)" "unprognostic (1.07e-1)" "unprognostic (2.35e-1)" "unprognostic (8.88e-2)" "unprognostic (1.50e-1)" "unprognostic (2.75e-1)" "unprognostic (2.09e-1)" "unprognostic (1.53e-1)" "unprognostic (4.09e-2)" "potential prognostic favorable (4.18e-5)" "unprognostic (4.91e-2)" "potential prognostic unfavorable (3.34e-4)" "unprognostic (6.87e-2)" "unprognostic (1.27e-2)" "unprognostic (3.05e-1)" "unprognostic (4.86e-1)" "unprognostic (5.52e-2)" "unprognostic (2.21e-3)" "unprognostic (2.97e-1)" "unprognostic (6.66e-3)" "unprognostic (1.42e-1)" "unprognostic (7.32e-2)" "unprognostic (3.63e-2)" "unprognostic (8.50e-3)" "unprognostic (2.05e-2)" "unprognostic (1.45e-1)" "unprognostic (1.79e-2)" "unprognostic (4.45e-1)" "unprognostic (1.84e-2)" "unprognostic (2.53e-1)" GMCL2 "GCL, GMCL1L, GMCL1P1" ENSG00000244234 "Germ cell-less 2, spermatogenesis associated" Q8NEA9 5 178184505-178187371 "Predicted intracellular proteins" "Differentiation, Spermatogenesis, Ubl conjugation pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 80 "testis: 17.9" "Cell type enriched" "Detected in some" 6 "Late primary spermatocytes: 184.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" HPA039579 Uncertain NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 23 "HPA039579: " GMDS "GMD, SDR3E1" ENSG00000112699 "GDP-mannose 4,6-dehydratase" O60547 6 1623806-2245605 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 99.8;salivary gland: 99.4;stomach 1: 91.7" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1582.6;Foveolar cells: 1577.2;Goblet cells: 1679.1;Lacrimal acinar cells: 2259.1;Mucous neck cells: 1792.9;Salivary acinar cells: 1694.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Colon Adenocarcinoma (TCGA): 175.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031528 Enhanced NA NA 23000 "Cluster 33: Non-specific - ATP binding" "Cluster 17: Intestine - Digestion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 7 "HPA031528: " "unprognostic (1.02e-1)" "unprognostic (1.68e-1)" "unprognostic (1.58e-1)" "unprognostic (8.66e-2)" "unprognostic (2.48e-1)" "unprognostic (9.19e-3)" "unprognostic (2.54e-1)" "unprognostic (2.87e-2)" "unprognostic (9.93e-2)" "unprognostic (3.42e-2)" "unprognostic (2.87e-3)" "unprognostic (4.05e-2)" "unprognostic (6.78e-2)" "potential prognostic unfavorable (3.50e-4)" "unprognostic (7.69e-2)" "unprognostic (5.30e-2)" "unprognostic (4.12e-2)" "unprognostic (1.15e-2)" "unprognostic (2.38e-1)" "unprognostic (2.32e-1)" "unprognostic (1.04e-1)" "unprognostic (2.11e-1)" "unprognostic (3.31e-3)" "unprognostic (4.03e-1)" "unprognostic (3.76e-2)" "unprognostic (1.11e-1)" "unprognostic (3.62e-2)" "unprognostic (3.68e-1)" "unprognostic (1.18e-1)" "potential prognostic unfavorable (4.48e-4)" "unprognostic (7.26e-3)" GMEB1 "P96PIF, PIF96" ENSG00000162419 "Glucocorticoid modulatory element binding protein 1" Q9Y692 1 28668778-28719353 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044811, HPA052975" Supported Enhanced Nucleoplasm NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 15: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 7: Non-specific - Transcription" 8 Nucleoplasm "HPA044811: , HPA052975: " "unprognostic (2.07e-2)" "unprognostic (6.08e-2)" "unprognostic (1.37e-1)" "potential prognostic unfavorable (2.08e-4)" "unprognostic (7.38e-2)" "unprognostic (1.55e-1)" "unprognostic (1.77e-1)" "unprognostic (2.47e-2)" "unprognostic (1.09e-1)" "unprognostic (4.18e-2)" "unprognostic (3.13e-3)" "unprognostic (4.59e-3)" "unprognostic (1.74e-1)" "potential prognostic unfavorable (4.78e-7)" "unprognostic (1.30e-1)" "unprognostic (1.28e-1)" "potential prognostic unfavorable (1.49e-4)" "unprognostic (3.54e-2)" "unprognostic (4.93e-1)" "unprognostic (7.07e-2)" "unprognostic (8.74e-2)" "unprognostic (1.96e-1)" "unprognostic (1.86e-1)" "unprognostic (5.92e-2)" "unprognostic (1.13e-1)" "unprognostic (1.83e-1)" "unprognostic (2.76e-2)" "unprognostic (1.29e-1)" "unprognostic (1.35e-1)" "unprognostic (2.34e-2)" "unprognostic (2.70e-2)" GMEB2 "KIAA1269, P79PIF, PIF79" ENSG00000101216 "Glucocorticoid modulatory element binding protein 2" Q9UKD1 20 63587602-63627101 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 66.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009706, HPA067455" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 24: Non-specific - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 62: Non-specific - Plasma proteins" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 19 Nucleoplasm Cytosol "HPA009706: , HPA067455: " "unprognostic (5.66e-3)" "unprognostic (2.40e-2)" "unprognostic (1.97e-2)" "unprognostic (1.73e-1)" "unprognostic (1.79e-1)" "unprognostic (5.86e-2)" "unprognostic (3.01e-1)" "unprognostic (7.70e-2)" "unprognostic (1.96e-2)" "unprognostic (7.00e-2)" "unprognostic (1.35e-2)" "unprognostic (1.75e-2)" "unprognostic (4.19e-2)" "unprognostic (1.18e-3)" "unprognostic (2.23e-2)" "unprognostic (6.11e-2)" "unprognostic (1.01e-1)" "unprognostic (9.89e-2)" "unprognostic (6.13e-3)" "unprognostic (4.17e-2)" "unprognostic (3.07e-2)" "unprognostic (7.72e-2)" "unprognostic (1.71e-2)" "unprognostic (9.63e-2)" "unprognostic (7.50e-2)" "unprognostic (6.02e-2)" "unprognostic (3.06e-1)" "unprognostic (3.98e-3)" "unprognostic (1.52e-1)" "unprognostic (4.70e-2)" "unprognostic (1.53e-1)" GMFB GMF ENSG00000197045 "Glia maturation factor beta" P60983 14 54474484-54489026 "Plasma proteins, Predicted intracellular proteins" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 98.2" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 117.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002954 Approved Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 860000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 7: Non-specific - Ribosome" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 4 "Nucleoplasm, Cytosol" "Nuclear bodies" "HPA002954: " "unprognostic (3.44e-2)" "unprognostic (3.07e-2)" "unprognostic (4.67e-2)" "unprognostic (1.78e-3)" "unprognostic (1.06e-1)" "unprognostic (7.44e-2)" "unprognostic (5.02e-2)" "unprognostic (3.13e-2)" "unprognostic (1.63e-2)" "unprognostic (4.10e-2)" "potential prognostic favorable (1.91e-6)" "unprognostic (2.00e-2)" "unprognostic (7.97e-2)" "potential prognostic unfavorable (3.62e-4)" "unprognostic (2.40e-2)" "unprognostic (1.47e-3)" "unprognostic (9.55e-2)" "unprognostic (1.83e-1)" "unprognostic (2.18e-1)" "unprognostic (5.85e-2)" "unprognostic (1.30e-3)" "unprognostic (1.86e-1)" "unprognostic (1.05e-2)" "unprognostic (1.16e-1)" "unprognostic (9.36e-2)" "unprognostic (3.10e-2)" "unprognostic (7.24e-2)" "unprognostic (2.20e-1)" "unprognostic (2.73e-1)" "unprognostic (8.66e-2)" "unprognostic (1.76e-1)" GMFG ENSG00000130755 "Glia maturation factor gamma" O60234 19 39328353-39342372 "Plasma proteins, Predicted intracellular proteins" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 544.6;lymphoid tissue: 428.5" "Cell type enhanced" "Detected in many" "cDC: 290.8;Hematopoietic stem cells: 286.8;Hofbauer cells: 741.5;Kupffer cells: 381.3;Megakaryocyte progenitors: 250.6;Megakaryocytes: 908.7;Monocyte progenitors: 296.6;monocytes: 457.3;Neutrophil progenitors: 534.3;Neutrophils: 1712.0;NK-cells: 245.9;Platelets: 453.9;T-cells: 299.5" "Cell type enhanced" "Detected in all" "leukocyte: 78.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 24 "Leukemia: 605.3;lymphoma: 229.6;Myeloma: 271.4" "Breast - Endothelial cells, Lung - Neutrophils_2, Minor Salivary Gland - Macrophages, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002954 Uncertain Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 2700000 "Cluster 35: Neutrophils - Protein binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 35: RS4;11 - Unknown function" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 3 "Nucleoplasm, Cytosol" "Nuclear bodies" "HPA002954: " "unprognostic (3.67e-2)" "unprognostic (1.32e-2)" "unprognostic (1.91e-1)" "unprognostic (1.93e-3)" "unprognostic (5.35e-2)" "unprognostic (2.59e-1)" "unprognostic (2.83e-2)" "unprognostic (1.89e-1)" "unprognostic (1.02e-2)" "unprognostic (7.19e-2)" "unprognostic (1.80e-2)" "unprognostic (2.75e-2)" "unprognostic (7.16e-2)" "unprognostic (1.17e-1)" "unprognostic (1.50e-1)" "unprognostic (1.31e-3)" "unprognostic (9.36e-2)" "unprognostic (4.55e-2)" "unprognostic (2.02e-1)" "unprognostic (1.94e-1)" "unprognostic (3.71e-1)" "unprognostic (1.84e-1)" "unprognostic (1.72e-2)" "unprognostic (1.01e-1)" "unprognostic (1.03e-1)" "unprognostic (4.16e-1)" "unprognostic (1.25e-1)" "unprognostic (1.63e-1)" "unprognostic (1.17e-2)" "unprognostic (7.48e-2)" "unprognostic (2.49e-1)" GMIP ARHGAP46 ENSG00000089639 "GEM interacting protein" Q9P107 19 19629476-19643657 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 48.1;lymphoid tissue: 52.0" "Cell type enhanced" "Detected in many" "Kupffer cells: 52.3;Microglia: 35.8;Monocyte progenitors: 34.9;monocytes: 57.3;Neutrophil progenitors: 88.9;Neutrophils: 221.9;Platelets: 69.1;T-cells: 34.3;Tuft cells: 34.6" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 43.2;leukocyte: 31.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adrenal gland - Macrophages, Lung - Neutrophils_2, Spleen - Neutrophils_2, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042484, HPA045481" Enhanced Enhanced "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 2 "Nucleoplasm, Cytosol" "Plasma membrane" "HPA042484: , HPA045481: " "unprognostic (6.87e-3)" "unprognostic (1.42e-1)" "unprognostic (4.81e-3)" "unprognostic (1.38e-1)" "unprognostic (6.40e-2)" "unprognostic (1.66e-1)" "unprognostic (9.62e-2)" "unprognostic (1.28e-2)" "unprognostic (5.65e-3)" "unprognostic (1.31e-1)" "unprognostic (2.32e-2)" "unprognostic (2.26e-1)" "unprognostic (2.39e-2)" "unprognostic (1.90e-3)" "unprognostic (8.41e-2)" "unprognostic (2.40e-3)" "unprognostic (6.79e-2)" "potential prognostic unfavorable (7.88e-4)" "unprognostic (7.08e-2)" "unprognostic (1.22e-1)" "unprognostic (5.27e-2)" "unprognostic (8.57e-2)" "unprognostic (2.28e-1)" "unprognostic (1.40e-2)" "unprognostic (7.13e-2)" "unprognostic (3.65e-3)" "unprognostic (3.83e-1)" "unprognostic (1.24e-2)" "unprognostic (2.92e-2)" "unprognostic (6.46e-2)" "unprognostic (1.44e-1)" GML LY6DL ENSG00000104499 "Glycosylphosphatidylinositol anchored molecule like" Q99445 8 142834247-142916506 "Predicted intracellular proteins, Transporters" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 56 "adrenal gland: 182.4" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 8.1;Early primary spermatocytes: 69.0;Early spermatids: 30.6;Late primary spermatocytes: 16.8;NK-cells: 7.9;Oocytes: 41.4;T-cells: 12.5;Undifferentiated spermatogonia: 34.2" "Cell type enhanced" "Detected in some" "hippocampal dentate gyrus: 6.2;leukocyte: 10.5;medium spiny neuron: 9.1" "Not detected" "Not detected" "Region enhanced" "Detected in some" "basal ganglia: 6.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Intracellular and membrane" "No annotated function" NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 33: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 3: Early primary spermatocytes - Early meiosis" 32 GMNC GEMC1 ENSG00000205835 "Geminin coiled-coil domain containing" A6NCL1 3 190852737-190892429 "Predicted intracellular proteins" "Cell cycle, DNA replication" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 2.8;fallopian tube: 7.6;liver: 3.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 78.0;Choroid plexus epithelial cells: 57.4;Early primary spermatocytes: 40.1;Early spermatids: 55.9;Endometrial ciliated cells: 40.0;Ependymal cells: 33.1;Epididymal efferent duct absorptive cells: 28.5;Epididymal efferent duct ciliated cells: 24.8;Fallopian tube ciliated cells: 27.0;Hepatocytes: 17.8;Late primary spermatocytes: 43.2;Late spermatids: 63.9" "Group enriched" "Detected in some" 18 "choroid plexus epithelial cell: 134.1;ependymal cell: 41.0" "Cancer enriched" "Detected in some" 5 "Ovary Serous Cystadenocarcinoma (TCGA): 5.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Pituitary gland - Corticotropes, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA043663 Uncertain NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 1 "HPA043663: " "unprognostic (1.12e-2)" "unprognostic (2.73e-1)" "unprognostic (4.06e-2)" "unprognostic (1.47e-1)" "unprognostic (2.72e-1)" GMNN Gem ENSG00000112312 "Geminin DNA replication inhibitor" O75496 6 24774931-24786099 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle" "DNA replication inhibitor" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 218.1" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 235.2;Endometrial luminal cells: 312.7;Enteric stem cells: 250.5;Enteric transient amplifying cells: 215.1;Late primary spermatocytes: 247.0;Oocytes: 432.9;Pancreatic duct cells: 215.2;Prostatic glandular cells: 197.4;Urothelial cells: 185.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011458, CAB047327, CAB047328, HPA049977, HPA054597" Enhanced Supported "Nucleoplasm,Basal body,Cytosol" Yes No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 8: Pancreas - Proteolysis" "Cluster 19: Astrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 34 Nucleoplasm "Basal body, Cytosol" "CAB011458: , CAB047327: , CAB047328: , HPA049977: , HPA054597: " "unprognostic (3.05e-2)" "unprognostic (5.99e-2)" "unprognostic (1.66e-2)" "unprognostic (5.47e-2)" "unprognostic (1.62e-1)" "unprognostic (7.64e-2)" "unprognostic (3.53e-2)" "unprognostic (1.31e-1)" "unprognostic (1.48e-1)" "unprognostic (2.49e-3)" "unprognostic (2.13e-3)" "unprognostic (4.95e-2)" "unprognostic (2.70e-3)" "unprognostic (8.39e-3)" "unprognostic (5.62e-3)" "unprognostic (1.73e-2)" "unprognostic (1.08e-2)" "unprognostic (5.22e-2)" "unprognostic (5.35e-2)" "unprognostic (2.41e-3)" "unprognostic (2.57e-1)" "potential prognostic unfavorable (1.17e-4)" "unprognostic (8.31e-3)" "unprognostic (2.66e-2)" "unprognostic (1.77e-2)" "unprognostic (2.54e-1)" "unprognostic (3.55e-3)" "unprognostic (1.13e-1)" "unprognostic (1.29e-1)" "unprognostic (3.28e-2)" "unprognostic (1.20e-1)" GMPPA ENSG00000144591 "GDP-mannose pyrophosphorylase A" Q96IJ6 2 219498865-219513898 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 67.7;Epididymal principal cells: 83.5;Extravillous trophoblasts: 107.8;Goblet cells: 62.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Pituitary gland - Somatotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035512, HPA035513" Approved Approved Nucleoplasm NA NA 17000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 70: Non-specific - Protein processing" "Cluster 12: Non-specific - Vasculature" "Cluster 63: Non-specific - Protein processing" "Cluster 8: Non-specific - Secretory pathway" 14 Nucleoplasm "HPA035512: , HPA035513: " "unprognostic (3.71e-2)" "unprognostic (1.56e-3)" "unprognostic (4.08e-2)" "unprognostic (2.43e-1)" "unprognostic (1.71e-1)" "unprognostic (1.20e-1)" "unprognostic (9.59e-2)" "unprognostic (8.69e-2)" "unprognostic (7.22e-2)" "unprognostic (3.21e-2)" "unprognostic (1.88e-1)" "unprognostic (4.85e-3)" "unprognostic (2.55e-1)" "validated prognostic unfavorable (2.38e-5)" "validated prognostic unfavorable (4.78e-4)" "unprognostic (4.37e-3)" "unprognostic (1.03e-3)" "unprognostic (2.06e-1)" "unprognostic (3.49e-2)" "unprognostic (3.19e-2)" "unprognostic (3.46e-1)" "unprognostic (2.45e-1)" "unprognostic (1.95e-1)" "unprognostic (1.73e-1)" "unprognostic (8.57e-2)" "unprognostic (2.49e-1)" "unprognostic (1.41e-1)" "unprognostic (4.68e-3)" "unprognostic (8.89e-2)" "unprognostic (2.16e-2)" "unprognostic (3.12e-1)" GMPPB KIAA1851 ENSG00000173540 "GDP-mannose pyrophosphorylase B" Q9Y5P6 3 49716844-49723973 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 142.5;Epididymal principal cells: 84.6;Esophageal apical cells: 143.2;Extravillous trophoblasts: 85.8;Plasma cells: 113.1;Syncytiotrophoblasts: 98.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014657 Uncertain NA NA 47000 "Cluster 13: Non-specific - Mitochondria" "Cluster 70: Non-specific - Protein processing" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Secretory pathway" 6 "HPA014657: " "unprognostic (3.08e-1)" "unprognostic (2.49e-1)" "unprognostic (1.57e-2)" "unprognostic (3.66e-2)" "unprognostic (8.19e-3)" "unprognostic (4.72e-2)" "unprognostic (7.75e-3)" "unprognostic (3.64e-2)" "unprognostic (1.43e-3)" "unprognostic (2.36e-2)" "unprognostic (1.45e-1)" "unprognostic (4.81e-2)" "unprognostic (1.59e-3)" "unprognostic (1.24e-2)" "unprognostic (6.58e-2)" "unprognostic (3.99e-3)" "unprognostic (1.62e-2)" "unprognostic (2.26e-2)" "unprognostic (1.86e-1)" "unprognostic (5.03e-2)" "unprognostic (1.08e-1)" "unprognostic (1.06e-1)" "unprognostic (1.03e-1)" "unprognostic (4.40e-2)" "unprognostic (2.62e-1)" "unprognostic (4.62e-2)" "unprognostic (3.46e-2)" "unprognostic (2.04e-1)" "unprognostic (1.22e-1)" "unprognostic (3.41e-2)" "unprognostic (4.76e-3)" GMPR ENSG00000137198 "Guanosine monophosphate reductase" P36959 6 16238587-16295549 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Purine metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 343.9;tongue: 191.3" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 547.6;Ependymal cells: 278.9;Erythrocyte progenitors: 294.5;Megakaryocytes: 253.4;Melanocytes: 356.3;Myonuclei: 294.5;Platelets: 763.1;Renal collecting duct intercalated cells: 288.3;Retinal pigment epithelial cells: 358.1;Undifferentiated spermatogonia: 353.0" "Cell type enhanced" "Detected in all" "astrocyte: 201.4;ependymal cell: 333.0" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 185.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 14.9" "Group enriched" "Detected in all" 6 "granulocytes: 14.9;monocytes: 5.0;NK-cells: 9.6" "Cancer enhanced" "Detected in many" "Leukemia: 41.9;skin cancer: 57.1" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Prostate - Prostate glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000904, HPA021476" Uncertain NA NA 710000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 1 "HPA000904: , HPA021476: " "unprognostic (7.49e-3)" "unprognostic (1.06e-1)" "unprognostic (8.82e-2)" "unprognostic (1.12e-1)" "unprognostic (2.58e-1)" "unprognostic (8.11e-3)" "unprognostic (3.05e-2)" "unprognostic (2.92e-2)" "unprognostic (3.65e-2)" "unprognostic (3.41e-2)" "unprognostic (1.33e-1)" "unprognostic (8.18e-2)" "unprognostic (6.17e-3)" "unprognostic (4.27e-1)" "unprognostic (1.16e-2)" "unprognostic (1.75e-3)" "unprognostic (1.14e-1)" "unprognostic (1.02e-1)" "unprognostic (1.48e-2)" "unprognostic (1.86e-3)" "unprognostic (8.42e-2)" "unprognostic (1.07e-1)" "unprognostic (1.72e-1)" "unprognostic (6.20e-2)" "unprognostic (3.20e-2)" "unprognostic (2.03e-1)" "unprognostic (1.64e-1)" "unprognostic (7.35e-2)" "unprognostic (1.53e-1)" "unprognostic (3.22e-2)" "unprognostic (3.73e-2)" GMPR2 ENSG00000100938 "Guanosine monophosphate reductase 2" Q9P2T1 14 24232422-24239242 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Purine metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglia: 12.0;Oligodendrocytes: 12.8;Other brain neurons: 13.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000904, HPA067884, HPA068782" Approved Approved Nucleoplasm,Nucleoli No No 110000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 45: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 98: Neurons - Neurotransmission & signaling" 6 Nucleoplasm Nucleoli "HPA000904: , HPA067884: , HPA068782: " "unprognostic (7.75e-2)" "unprognostic (1.77e-2)" "unprognostic (9.66e-3)" "unprognostic (1.64e-2)" "unprognostic (1.55e-1)" "unprognostic (2.57e-1)" "unprognostic (1.38e-2)" "unprognostic (2.08e-2)" "unprognostic (4.59e-3)" "unprognostic (5.76e-3)" "potential prognostic favorable (4.95e-7)" "unprognostic (6.27e-3)" "unprognostic (4.32e-2)" "unprognostic (9.73e-2)" "unprognostic (5.45e-2)" "unprognostic (7.41e-2)" "unprognostic (8.64e-2)" "unprognostic (9.12e-3)" "unprognostic (7.26e-3)" "unprognostic (2.02e-2)" "unprognostic (1.15e-1)" "unprognostic (7.19e-2)" "unprognostic (1.01e-1)" "unprognostic (9.12e-3)" "unprognostic (2.13e-1)" "unprognostic (2.11e-1)" "unprognostic (7.15e-3)" "unprognostic (2.11e-1)" "unprognostic (9.77e-2)" "unprognostic (4.30e-1)" "unprognostic (9.01e-2)" GMPS GATD7 ENSG00000163655 "Guanine monophosphate synthase" P49915 3 155870650-155944020 "Disease related genes, Enzymes, Essential proteins, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "GMP biosynthesis, Purine biosynthesis" Ligase Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 93.8" "Cell type enhanced" "Detected in all" "Early spermatids: 228.7;Late primary spermatocytes: 467.6;Late spermatids: 267.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046630 Supported Mitochondria,Cytosol No No 53000 "Cluster 33: Non-specific - ATP binding" "Cluster 39: Testis - Nuclear processes" "Cluster 16: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 10 "Mitochondria, Cytosol" "HPA046630: " "unprognostic (1.08e-2)" "unprognostic (2.82e-2)" "unprognostic (3.15e-1)" "unprognostic (1.16e-2)" "unprognostic (7.90e-3)" "unprognostic (2.30e-1)" "unprognostic (2.41e-1)" "unprognostic (6.78e-2)" "unprognostic (3.14e-2)" "unprognostic (6.53e-3)" "unprognostic (3.38e-3)" "unprognostic (7.38e-2)" "potential prognostic unfavorable (4.26e-4)" "validated prognostic unfavorable (3.28e-6)" "validated prognostic unfavorable (3.44e-5)" "validated prognostic unfavorable (1.26e-4)" "validated prognostic unfavorable (1.78e-4)" "unprognostic (2.06e-2)" "unprognostic (1.84e-1)" "unprognostic (5.98e-2)" "unprognostic (4.20e-2)" "validated prognostic unfavorable (6.88e-6)" "validated prognostic unfavorable (3.90e-4)" "unprognostic (2.29e-3)" "unprognostic (8.73e-2)" "unprognostic (8.60e-2)" "unprognostic (1.97e-2)" "unprognostic (1.77e-1)" "unprognostic (3.53e-1)" "potential prognostic unfavorable (6.37e-4)" "unprognostic (3.39e-3)" GNA11 "FBH, FBH2, FHH2, HHC2" ENSG00000088256 "G protein subunit alpha 11" P29992 19 3094362-3123999 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Host-virus interaction" "Hydrolase, Transducer" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 219.0;Enterocytes: 313.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 5.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048886 Approved NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 15: Non-specific - Transcription" "Cluster 23: Non-specific - Transcription" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 21 "HPA048886: " "unprognostic (4.07e-2)" "unprognostic (1.01e-2)" "unprognostic (3.41e-1)" "unprognostic (2.42e-2)" "unprognostic (3.50e-2)" "unprognostic (1.19e-1)" "unprognostic (2.76e-1)" "unprognostic (3.12e-2)" "unprognostic (2.58e-2)" "unprognostic (9.66e-2)" "potential prognostic favorable (8.35e-7)" "unprognostic (1.08e-2)" "unprognostic (2.25e-2)" "unprognostic (1.79e-2)" "unprognostic (2.93e-2)" "unprognostic (4.67e-3)" "unprognostic (1.88e-2)" "unprognostic (2.74e-1)" "unprognostic (1.27e-3)" "unprognostic (3.99e-2)" "unprognostic (2.06e-1)" "unprognostic (6.38e-2)" "unprognostic (4.92e-2)" "unprognostic (2.20e-1)" "unprognostic (6.63e-2)" "unprognostic (3.72e-1)" "unprognostic (3.01e-2)" "unprognostic (7.20e-2)" "unprognostic (1.65e-1)" "unprognostic (3.90e-1)" "unprognostic (4.13e-2)" GNA12 gep ENSG00000146535 "G protein subunit alpha 12" Q03113 7 2728105-2844308 "Human disease related genes, Predicted intracellular proteins" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "cDC: 279.4;Cytotrophoblasts: 308.8;Somatotrophs: 340.4;Syncytiotrophoblasts: 699.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010046 Approved Supported Cytosol NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 82: Dendritic cells - Antigen presentation" 7 Cytosol "CAB010046: " "unprognostic (1.07e-1)" "unprognostic (1.14e-1)" "unprognostic (2.14e-1)" "unprognostic (1.08e-3)" "unprognostic (1.07e-1)" "unprognostic (1.92e-1)" "unprognostic (6.91e-2)" "unprognostic (1.06e-3)" "unprognostic (2.98e-2)" "unprognostic (1.29e-1)" "potential prognostic favorable (1.09e-4)" "unprognostic (8.62e-2)" "unprognostic (7.03e-2)" "potential prognostic unfavorable (7.06e-4)" "unprognostic (1.51e-2)" "unprognostic (3.04e-3)" "potential prognostic unfavorable (9.59e-4)" "unprognostic (6.05e-2)" "unprognostic (3.26e-1)" "unprognostic (2.38e-2)" "unprognostic (2.72e-2)" "unprognostic (6.70e-3)" "unprognostic (1.33e-2)" "unprognostic (1.05e-1)" "unprognostic (2.95e-1)" "unprognostic (1.09e-1)" "unprognostic (4.07e-1)" "unprognostic (2.41e-1)" "unprognostic (2.89e-1)" "unprognostic (3.43e-2)" "unprognostic (1.14e-2)" GNA13 "G13, MGC46138" ENSG00000120063 "G protein subunit alpha 13" Q14344 17 65009289-65056740 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Transducer "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 136.4" "Cell type enhanced" "Detected in all" "cDC: 549.6;Macrophages: 397.4;monocytes: 427.9;Neutrophils: 778.3;Platelets: 283.8" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 227.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010087 Approved Supported Cytosol NA NA 630000 "Cluster 28: Neutrophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 82: Dendritic cells - Antigen presentation" 46 Cytosol "HPA010087: " "unprognostic (6.61e-3)" "unprognostic (2.23e-1)" "unprognostic (1.96e-1)" "unprognostic (7.34e-2)" "unprognostic (5.26e-2)" "unprognostic (1.66e-1)" "unprognostic (1.58e-1)" "unprognostic (4.48e-2)" "unprognostic (1.16e-1)" "potential prognostic unfavorable (8.14e-4)" "potential prognostic favorable (5.75e-6)" "unprognostic (5.47e-2)" "unprognostic (5.33e-2)" "unprognostic (1.37e-2)" "unprognostic (1.93e-2)" "unprognostic (1.29e-2)" "unprognostic (4.21e-3)" "unprognostic (1.29e-1)" "unprognostic (1.59e-1)" "unprognostic (9.18e-2)" "unprognostic (1.14e-2)" "unprognostic (1.82e-2)" "unprognostic (2.47e-2)" "unprognostic (8.71e-2)" "unprognostic (5.82e-2)" "unprognostic (3.50e-2)" "unprognostic (6.79e-2)" "unprognostic (3.92e-2)" "unprognostic (5.46e-1)" "unprognostic (5.14e-2)" "unprognostic (7.63e-2)" GNA14 ENSG00000156049 "G protein subunit alpha 14" O95837 9 77423079-77648322 "Predicted intracellular proteins" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 374.8;Choroid plexus epithelial cells: 319.0;Goblet cells: 195.6;Myosatellite cells: 269.5;Pituitary stem cells: 290.4;Prostatic club cells: 157.3;Respiratory ciliated cells: 657.0;Respiratory deuterosomal cells: 167.9;Transitional alveolar cells: 160.4;Tuft cells: 184.5;Vascular endothelial cells: 292.6" "Cell type enhanced" "Detected in all" "astrocyte: 291.4;choroid plexus epithelial cell: 281.8;hippocampal dentate gyrus: 273.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 96 "basophil: 27.4" "Lineage enriched" "Detected in single" 96 "granulocytes: 27.4" "Group enriched" "Detected in some" 7 "Bone cancer: 14.9;Rhabdoid: 4.5" "Skin - Endothelial cells, Spleen - Fibroblasts_1, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA048886 Approved NA NA "Cluster 41: Basophils - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 23: Choroid plexus - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 3 "HPA048886: " "unprognostic (2.49e-1)" "unprognostic (1.66e-2)" "unprognostic (3.36e-1)" "potential prognostic favorable (8.88e-4)" "unprognostic (1.35e-1)" "unprognostic (2.83e-2)" "unprognostic (4.19e-1)" "unprognostic (1.44e-1)" "unprognostic (3.47e-2)" "validated prognostic favorable (3.83e-12)" "validated prognostic favorable (7.53e-4)" "potential prognostic favorable (8.55e-9)" "potential prognostic favorable (6.93e-4)" "unprognostic (9.69e-2)" "unprognostic (2.19e-2)" "unprognostic (1.91e-2)" "unprognostic (1.18e-1)" "unprognostic (2.16e-2)" "unprognostic (4.19e-1)" "unprognostic (4.26e-2)" "unprognostic (2.39e-3)" "unprognostic (4.86e-1)" "potential prognostic unfavorable (1.94e-4)" "unprognostic (2.25e-1)" "potential prognostic unfavorable (4.26e-4)" "unprognostic (1.17e-1)" GNA15 GNA16 ENSG00000060558 "G protein subunit alpha 15" P30679 19 3136033-3163749 "Plasma proteins, Predicted intracellular proteins" Transducer "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 71.2;esophagus: 99.4" "Cell type enriched" "Detected in many" 4 "Esophageal apical cells: 1211.3" "Cell type enriched" "Detected in some" 4 "central nervous system macrophage: 30.4" "Cancer enhanced" "Detected in all" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 70.4;Head and Neck Squamous Cell Carcinoma (TCGA): 74.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 67.2" "Group enriched" "Detected in many" 4 "dendritic cells: 67.2;granulocytes: 19.3;monocytes: 29.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 43.1;Leukemia: 87.7" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Pituitary gland - Macrophages, Skeletal muscle - Macrophages, Spleen - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043113 Approved NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 12: Non-specific - Vasculature" "Cluster 59: Leukemia - T-cell receptor" "Cluster 84: Apical squamous epithelium - Cornification" 2 "HPA043113: " "unprognostic (3.47e-1)" "unprognostic (8.94e-3)" "unprognostic (5.70e-2)" "unprognostic (7.13e-3)" "unprognostic (2.11e-1)" "unprognostic (3.29e-1)" "unprognostic (2.22e-2)" "unprognostic (4.40e-1)" "unprognostic (3.13e-1)" "unprognostic (1.71e-1)" "unprognostic (5.53e-3)" "unprognostic (1.84e-1)" "unprognostic (2.75e-3)" "unprognostic (2.79e-2)" "unprognostic (1.89e-1)" "unprognostic (1.39e-1)" "unprognostic (9.06e-3)" "unprognostic (1.51e-2)" "unprognostic (1.13e-2)" "unprognostic (6.32e-3)" "unprognostic (5.71e-2)" "potential prognostic unfavorable (6.75e-4)" "unprognostic (1.41e-2)" "unprognostic (2.61e-1)" "unprognostic (7.99e-2)" "unprognostic (1.87e-1)" "unprognostic (2.07e-1)" "unprognostic (1.15e-1)" "unprognostic (1.54e-2)" "unprognostic (1.61e-1)" "potential prognostic favorable (6.25e-4)" GNAI1 ENSG00000127955 "G protein subunit alpha i1" P63096 7 79768028-80226181 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Host-virus interaction, Mitosis, Transport" "Hydrolase, Transducer" "Cancer-related genes, Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 37.1" "Cell type enhanced" "Detected in many" "Adipocytes: 280.6;Basal keratinocytes: 317.3;Loop of henle epithelial cells: 253.1;Oligodendrocytes: 505.9;Suprabasal keratinocytes: 295.5;Syncytiotrophoblasts: 280.5" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 494.9;oligodendrocyte: 625.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "NK-cell: 12.8" "Lineage enriched" "Detected in many" 6 "NK-cells: 12.8" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Lung - Fibroblasts_1, Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Smooth muscle cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022449, HPA042141" Approved Supported "Nucleoplasm,Nucleoli,Golgi apparatus,Centriolar satellite,Centrosome,Basal body,Cytosol,Principal piece" NA NA 1900000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 89: Adipocytes - Lipid metabolism" 38 "Centrosome, Principal piece" "Nucleoplasm, Nucleoli, Golgi apparatus, Centriolar satellite, Basal body, Cytosol" "CAB022449: , HPA042141: " "unprognostic (1.15e-2)" "unprognostic (1.06e-1)" "unprognostic (1.24e-1)" "unprognostic (1.46e-3)" "unprognostic (2.68e-1)" "unprognostic (1.73e-1)" "unprognostic (8.33e-2)" "potential prognostic favorable (6.96e-4)" "unprognostic (3.39e-1)" "unprognostic (2.42e-2)" "validated prognostic favorable (4.69e-5)" "validated prognostic favorable (5.00e-4)" "unprognostic (4.65e-2)" "unprognostic (2.24e-2)" "unprognostic (1.01e-2)" "unprognostic (3.11e-3)" "unprognostic (2.14e-1)" "unprognostic (1.13e-1)" "unprognostic (1.40e-2)" "unprognostic (5.63e-2)" "unprognostic (1.02e-1)" "unprognostic (5.69e-2)" "unprognostic (8.31e-3)" "unprognostic (3.13e-1)" "unprognostic (2.10e-1)" "unprognostic (1.62e-1)" "potential prognostic unfavorable (1.51e-4)" "potential prognostic unfavorable (4.45e-4)" "unprognostic (9.80e-2)" "unprognostic (1.81e-2)" "unprognostic (1.75e-1)" GNAI2 "GIP, GNAI2B" ENSG00000114353 "G protein subunit alpha i2" P04899 3 50226292-50259362 "Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 484.1;Late spermatids: 487.7;Monocyte progenitors: 498.2;monocytes: 676.1;Neutrophil progenitors: 445.2;Neutrophils: 1060.3" "Cell type enhanced" "Detected in all" "endothelial cell: 265.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Lung - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007704 Approved Supported "Nucleoplasm,Plasma membrane,Basal body,Cytosol" NA NA 7300000 "Cluster 7: Non-specific - Innate immune response" "Cluster 5: Spleen - Immune response" "Cluster 39: Astrocytes - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 38 Cytosol "Nucleoplasm, Plasma membrane, Basal body" "HPA007704: " "unprognostic (3.03e-2)" "unprognostic (1.47e-2)" "unprognostic (2.01e-1)" "unprognostic (9.59e-2)" "unprognostic (2.19e-1)" "unprognostic (1.26e-1)" "unprognostic (4.03e-1)" "unprognostic (2.88e-2)" "unprognostic (1.08e-1)" "unprognostic (4.76e-2)" "potential prognostic favorable (7.04e-4)" "unprognostic (5.58e-3)" "unprognostic (3.41e-1)" "unprognostic (3.18e-3)" "unprognostic (1.05e-1)" "unprognostic (1.62e-1)" "unprognostic (5.28e-3)" "unprognostic (7.12e-2)" "unprognostic (8.62e-2)" "unprognostic (1.50e-1)" "unprognostic (5.47e-1)" "unprognostic (1.58e-1)" "unprognostic (4.70e-2)" "unprognostic (3.07e-1)" "unprognostic (1.94e-2)" "unprognostic (6.37e-3)" "unprognostic (4.49e-2)" "unprognostic (8.58e-2)" "unprognostic (5.15e-2)" "unprognostic (3.37e-1)" "unprognostic (1.80e-1)" GNAI3 87U6 ENSG00000065135 "G protein subunit alpha i3" P08754 1 109548615-109600195 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" Transducer "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 759.6;Neutrophils: 1086.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022099, HPA042141" Approved Supported "Nucleoplasm,Nucleoli,Golgi apparatus,Centriolar satellite,Centrosome,Basal body,Cytosol,Principal piece" NA NA 1800000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 37: Non-specific - mRNA processing" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 53 "Centrosome, Principal piece" "Nucleoplasm, Nucleoli, Golgi apparatus, Centriolar satellite, Basal body, Cytosol" "CAB022099: , HPA042141: " "unprognostic (7.77e-2)" "unprognostic (1.82e-1)" "unprognostic (3.44e-2)" "unprognostic (7.22e-2)" "potential prognostic favorable (3.29e-4)" "unprognostic (3.55e-1)" "unprognostic (2.75e-1)" "unprognostic (5.34e-1)" "unprognostic (6.80e-2)" "unprognostic (2.42e-2)" "potential prognostic favorable (5.45e-7)" "unprognostic (7.14e-3)" "unprognostic (1.87e-1)" "validated prognostic unfavorable (1.71e-6)" "validated prognostic unfavorable (3.93e-4)" "validated prognostic unfavorable (4.05e-4)" "validated prognostic unfavorable (3.95e-4)" "unprognostic (2.27e-1)" "unprognostic (1.78e-1)" "unprognostic (6.66e-3)" "unprognostic (1.79e-2)" "unprognostic (1.36e-3)" "unprognostic (8.31e-2)" "unprognostic (7.05e-2)" "unprognostic (3.27e-2)" "unprognostic (1.75e-1)" "unprognostic (8.96e-2)" "unprognostic (1.94e-1)" "unprognostic (2.42e-1)" "unprognostic (4.14e-3)" "unprognostic (7.66e-2)" GNAL ENSG00000141404 "G protein subunit alpha L" P38405 18 11689264-11885685 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Hydrolase, Transducer" "Disease variant, Dystonia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 63.4" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 469.0;Lactotrophs: 576.7;Somatotrophs: 769.5;Thyrotrophs: 587.8" "Cell type enhanced" "Detected in all" "eccentric medium spiny neuron: 743.1;medium spiny neuron: 1131.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.3" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in many" 12 "Adrenocortical cancer: 67.3" "Minor Salivary Gland - Endothelial cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 13 "basal ganglia: 218.4" HPA051160 Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 35: Neurons - Synaptic function & neurogenesis" "Plasma membrane, Cytosol" "HPA051160: " "unprognostic (2.64e-3)" "unprognostic (6.93e-3)" "unprognostic (1.66e-1)" "unprognostic (2.85e-1)" "unprognostic (1.33e-1)" "unprognostic (3.92e-1)" "unprognostic (6.07e-2)" "unprognostic (1.01e-2)" "unprognostic (7.76e-3)" "unprognostic (9.86e-2)" "unprognostic (3.72e-2)" "unprognostic (2.59e-2)" "unprognostic (1.95e-2)" "unprognostic (1.46e-2)" "unprognostic (2.41e-2)" "unprognostic (1.77e-2)" "unprognostic (5.03e-3)" "unprognostic (8.27e-2)" "unprognostic (1.75e-1)" "unprognostic (9.69e-2)" "unprognostic (4.92e-3)" "unprognostic (1.61e-2)" "unprognostic (5.96e-2)" "potential prognostic unfavorable (2.38e-4)" "unprognostic (1.55e-1)" "unprognostic (1.70e-1)" "unprognostic (1.24e-1)" "unprognostic (1.24e-1)" "potential prognostic unfavorable (3.53e-4)" "unprognostic (6.58e-2)" GNAO1 G-ALPHA-o ENSG00000087258 "G protein subunit alpha o1" P09471 16 56191390-56357444 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Hydrolase, Transducer" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 133.2;retina: 48.0" "Cell type enhanced" "Detected in many" "Astrocytes: 298.3;Bergmann glia: 458.2;Brain excitatory neurons: 233.9;Brain inhibitory neurons: 255.0;Epididymal efferent duct absorptive cells: 184.8;Gonadotrophs: 242.6;Lactotrophs: 254.0;Oligodendrocytes: 622.5;Other brain neurons: 238.6;Retinal amacrine cells: 170.8;Retinal bipolar cells: 454.7;Somatotrophs: 235.2;Thyrotrophs: 265.1" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 5 "Glioblastoma Multiforme (TCGA): 29.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 37.9" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal medulla cells, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Alpha cells, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "CAB008387, HPA040878" Enhanced NA NA 800000 "Cluster 73: Brain - Neuronal signaling" "Cluster 34: Non-specific - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 20 "CAB008387: , HPA040878: " "unprognostic (3.39e-2)" "unprognostic (2.08e-1)" "unprognostic (1.56e-2)" "unprognostic (1.06e-2)" "unprognostic (2.07e-1)" "unprognostic (4.02e-2)" "unprognostic (2.41e-1)" "unprognostic (1.38e-3)" "unprognostic (7.03e-2)" "unprognostic (1.89e-1)" "potential prognostic favorable (4.17e-4)" "unprognostic (1.77e-3)" "unprognostic (2.60e-1)" "unprognostic (5.97e-2)" "unprognostic (2.84e-1)" "unprognostic (2.78e-1)" "unprognostic (1.78e-1)" "potential prognostic favorable (8.33e-4)" "unprognostic (2.63e-2)" "unprognostic (1.54e-1)" "unprognostic (6.10e-2)" "unprognostic (6.04e-2)" "unprognostic (1.18e-2)" "unprognostic (2.47e-1)" "unprognostic (2.17e-1)" GNAQ "G-ALPHA-q, GAQ" ENSG00000156052 "G protein subunit alpha q" P50148 9 77716097-78031811 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Hydrolase, Transducer" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 2052.7;Neutrophils: 3046.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 26.9" "Lineage enriched" "Detected in many" 6 "granulocytes: 26.9" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "CAB010036, HPA048886" Uncertain Approved "Nuclear speckles,Plasma membrane,Cytosol" NA NA 460000 "Cluster 41: Basophils - Unknown function" "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 20 "Nuclear speckles, Plasma membrane" Cytosol "CAB010036: , HPA048886: " "unprognostic (1.80e-1)" "unprognostic (1.48e-1)" "unprognostic (5.74e-2)" "unprognostic (3.79e-2)" "unprognostic (2.50e-1)" "unprognostic (3.48e-3)" "unprognostic (4.05e-1)" "unprognostic (2.15e-1)" "unprognostic (1.18e-1)" "unprognostic (3.61e-1)" "validated prognostic favorable (6.35e-7)" "validated prognostic favorable (2.30e-4)" "unprognostic (1.34e-1)" "unprognostic (1.02e-1)" "unprognostic (8.43e-2)" "unprognostic (2.27e-2)" "unprognostic (3.99e-2)" "unprognostic (5.08e-2)" "unprognostic (3.05e-1)" "unprognostic (2.51e-1)" "unprognostic (1.64e-2)" "unprognostic (2.17e-1)" "unprognostic (1.22e-2)" "unprognostic (9.63e-2)" "unprognostic (4.12e-2)" "unprognostic (3.96e-1)" "unprognostic (7.59e-2)" "unprognostic (9.97e-2)" "unprognostic (2.73e-1)" "unprognostic (4.26e-2)" "unprognostic (2.83e-1)" GNAS "GNAS1, GNASXL, GPSA, NESP, NESP55, SCG6, SgVI" ENSG00000087460 "GNAS complex locus" "O95467, P63092, Q5JWF2" 20 58839718-58911192 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrolase, Transducer" "Cancer-related genes, Cushing syndrome, Disease variant, Dwarfism, Obesity, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Lactotrophs: 4354.4;Late spermatids: 2985.7;Pancreatic islet cells: 6202.3;Platelets: 3230.5;Somatotrophs: 4131.7;Thyrotrophs: 4260.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010337, HPA018122, HPA027478, HPA028386" Uncertain Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 1: Neurons - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 30 Nucleoplasm "Plasma membrane, Cytosol" "CAB010337: , HPA018122: , HPA027478: , HPA028386: " "unprognostic (4.49e-2)" "unprognostic (7.56e-2)" "unprognostic (5.38e-2)" "unprognostic (3.67e-2)" "unprognostic (1.80e-1)" "unprognostic (1.24e-2)" "unprognostic (5.21e-2)" "unprognostic (6.88e-2)" "unprognostic (1.40e-2)" "unprognostic (1.93e-1)" "unprognostic (7.49e-3)" "unprognostic (3.03e-2)" "unprognostic (5.53e-2)" "unprognostic (4.92e-3)" "unprognostic (3.84e-3)" "unprognostic (2.11e-2)" "potential prognostic unfavorable (3.14e-4)" "unprognostic (2.57e-1)" "unprognostic (2.36e-2)" "unprognostic (9.63e-2)" "unprognostic (2.53e-1)" "unprognostic (5.12e-2)" "unprognostic (7.06e-3)" "unprognostic (1.46e-1)" "unprognostic (4.64e-2)" "unprognostic (5.81e-2)" "unprognostic (5.11e-2)" "unprognostic (1.02e-3)" "unprognostic (4.25e-1)" "unprognostic (9.25e-2)" "unprognostic (2.64e-1)" GNAT1 CSNBAD3 ENSG00000114349 "G protein subunit alpha transducin 1" P11488 3 50191610-50197696 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" Transducer "Congenital stationary night blindness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 944 "retina: 1040.7" "Cell type enriched" "Detected in some" 16 "Rod photoreceptor cells: 1217.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in some" 6 "hippocampal formation: 6.5" "Not detected" "Not detected" HPA045393 Enhanced Approved "Mid piece,Principal piece,End piece" NA NA "Cluster 42: Retina - Visual perception" "Cluster 9: Non-specific - Receptor signaling" "Cluster 1: Neuronal - Visual perception" "Cluster 79: Photoreceptor cells - Phototransduction" "Mid piece, Principal piece, End piece" "HPA045393: " "unprognostic (1.58e-1)" "unprognostic (1.03e-2)" GNAT2 ACHM4 ENSG00000134183 "G protein subunit alpha transducin 2" P19087 1 109603091-109619929 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" Transducer "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 29 "retina: 73.0" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 116.3;Cone photoreceptor cells: 229.8;Epicardial cells: 47.8;Neutrophils: 19.1" "Low cell type specificity" "Detected in some" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 2.3;eosinophil: 2.5;neutrophil: 3.7" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.7" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 42: Retina - Visual perception" "Cluster 23: Choroid plexus - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 6 "unprognostic (8.19e-2)" "unprognostic (2.60e-1)" GNAT3 "GDCA, gustducin" ENSG00000214415 "G protein subunit alpha transducin 3" A8MTJ3 7 80458635-80512064 "Predicted intracellular proteins" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "intestine: 1.7" "Cell type enriched" "Detected in some" 6 "Lymphatic endothelial cells: 46.0" "Cell type enriched" "Detected in some" 14 "deep-layer near-projecting: 15.0" "Group enriched" "Detected in some" 5 "Bladder Urothelial Carcinoma (TCGA): 1.8;Breast Invasive Carcinoma (TCGA): 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "colorectal cancer: 6.2;thyroid cancer: 5.5" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Region enriched" "Detected in single" 6 "olfactory bulb: 1.0" HPA071345 Enhanced Approved "Vesicles,Basal body" NA NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 24: Non-specific - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 1 Vesicles "Basal body" "HPA071345: " "potential prognostic unfavorable (9.50e-5)" "unprognostic (6.29e-1)" GNAZ ENSG00000128266 "G protein subunit alpha z" P19086 22 23070519-23125032 "Predicted intracellular proteins" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 45.1" "Group enriched" "Detected in many" 4 "Megakaryocytes: 247.3;Platelets: 338.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 16.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Kidney - Fibroblasts, Minor Salivary Gland - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003011 Enhanced Approved Vesicles NA NA 260000 "Cluster 20: Non-specific - DNA binding" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 51: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 47: Platelets - Hemostasis" 5 Vesicles "HPA003011: " "unprognostic (2.25e-2)" "unprognostic (7.56e-2)" "unprognostic (1.43e-1)" "unprognostic (6.01e-2)" "unprognostic (4.84e-3)" "unprognostic (1.37e-1)" "unprognostic (2.12e-1)" "unprognostic (5.20e-2)" "unprognostic (1.11e-1)" "unprognostic (1.29e-2)" "unprognostic (1.79e-2)" "unprognostic (1.79e-2)" "unprognostic (2.20e-1)" "potential prognostic unfavorable (7.45e-4)" "unprognostic (1.27e-2)" "unprognostic (9.00e-3)" "unprognostic (7.56e-2)" "unprognostic (4.24e-1)" "unprognostic (1.18e-2)" "unprognostic (1.63e-1)" "unprognostic (1.95e-1)" "unprognostic (3.85e-3)" "unprognostic (1.11e-1)" "unprognostic (2.97e-3)" "unprognostic (5.72e-2)" "unprognostic (8.83e-3)" "unprognostic (4.48e-3)" "unprognostic (1.79e-1)" "unprognostic (3.69e-2)" "unprognostic (1.94e-1)" "unprognostic (3.83e-2)" GNB1 ENSG00000078369 "G protein subunit beta 1" P62873 1 1785285-1892292 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins, Transporters" "Host-virus interaction" Transducer "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "retina: 2147.2" "Cell type enhanced" "Detected in all" "Neutrophils: 1581.2;Rod photoreceptor cells: 2097.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Lung - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040736, HPA074924" Supported Approved "Golgi apparatus,Plasma membrane" NA NA 4000000 "Cluster 29: Non-specific - Unknown function" "Cluster 42: Retina - Visual perception" "Cluster 14: Neurons - Synaptic function" "Cluster 37: Non-specific - mRNA processing" "Cluster 79: Photoreceptor cells - Phototransduction" 135 "Plasma membrane" "Golgi apparatus" "HPA040736: , HPA074924: " "unprognostic (1.43e-1)" "unprognostic (4.42e-2)" "unprognostic (2.79e-2)" "unprognostic (1.63e-3)" "unprognostic (7.37e-3)" "unprognostic (2.39e-2)" "unprognostic (2.25e-1)" "unprognostic (1.84e-2)" "unprognostic (9.12e-2)" "potential prognostic unfavorable (4.08e-5)" "potential prognostic favorable (2.03e-6)" "unprognostic (4.58e-3)" "unprognostic (6.02e-3)" "validated prognostic unfavorable (8.48e-5)" "validated prognostic unfavorable (1.16e-4)" "unprognostic (8.38e-2)" "unprognostic (6.15e-3)" "potential prognostic unfavorable (6.48e-4)" "unprognostic (1.52e-1)" "unprognostic (1.86e-1)" "unprognostic (4.21e-1)" "unprognostic (2.10e-2)" "unprognostic (1.86e-1)" "unprognostic (2.86e-1)" "unprognostic (2.88e-1)" "unprognostic (6.34e-2)" "unprognostic (2.05e-1)" "unprognostic (2.25e-1)" "unprognostic (8.07e-2)" "unprognostic (5.54e-2)" "unprognostic (1.35e-1)" GNB1L "GY2, WDR14" ENSG00000185838 "G protein subunit beta 1 like" Q9BYB4 22 19783223-19854939 "Essential proteins, Predicted intracellular proteins" "DNA damage" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 43.7;Endometrial luminal cells: 31.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034627, HPA034628" Approved Approved Cytosol NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 2 Cytosol "HPA034627: , HPA034628: " "unprognostic (2.01e-3)" "unprognostic (3.20e-2)" "unprognostic (1.30e-2)" "unprognostic (2.67e-2)" "unprognostic (6.33e-2)" "unprognostic (6.68e-3)" "unprognostic (8.38e-2)" "unprognostic (1.15e-3)" "unprognostic (4.53e-2)" "unprognostic (1.28e-2)" "validated prognostic unfavorable (5.25e-4)" "validated prognostic unfavorable (7.33e-4)" "unprognostic (5.97e-2)" "potential prognostic unfavorable (1.06e-5)" "unprognostic (9.49e-2)" "potential prognostic unfavorable (3.10e-4)" "unprognostic (2.15e-2)" "unprognostic (1.04e-1)" "unprognostic (1.35e-1)" "unprognostic (5.67e-2)" "unprognostic (1.44e-1)" "unprognostic (7.97e-2)" "unprognostic (6.66e-2)" "unprognostic (2.62e-1)" "unprognostic (8.57e-3)" "unprognostic (1.23e-2)" "unprognostic (6.50e-3)" "unprognostic (1.97e-2)" "unprognostic (2.90e-2)" "unprognostic (1.05e-1)" GNB2 ENSG00000172354 "G protein subunit beta 2" P62879 7 100673567-100679174 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins, Transporters" Transducer "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1493.9;Esophageal suprabasal cells: 574.4;Neutrophils: 574.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010032, HPA040736, HPA074924" Approved Supported "Plasma membrane" NA NA 3200000 "Cluster 21: Neutrophils - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 33: Neurons - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 161 "Plasma membrane" "CAB010032: , HPA040736: , HPA074924: " "unprognostic (6.88e-2)" "unprognostic (2.78e-1)" "unprognostic (7.53e-2)" "unprognostic (6.48e-2)" "unprognostic (2.27e-1)" "unprognostic (8.08e-3)" "unprognostic (1.21e-2)" "unprognostic (7.78e-2)" "unprognostic (2.78e-1)" "unprognostic (2.10e-2)" "potential prognostic favorable (1.72e-5)" "unprognostic (6.26e-2)" "unprognostic (3.55e-2)" "unprognostic (4.62e-3)" "potential prognostic unfavorable (1.71e-5)" "unprognostic (1.16e-1)" "potential prognostic unfavorable (8.45e-4)" "unprognostic (4.42e-1)" "unprognostic (4.35e-1)" "unprognostic (1.64e-1)" "unprognostic (1.27e-1)" "unprognostic (1.09e-2)" "unprognostic (9.18e-2)" "unprognostic (1.66e-1)" "unprognostic (1.43e-2)" "unprognostic (1.24e-1)" "unprognostic (4.94e-2)" "unprognostic (7.98e-2)" "unprognostic (1.62e-1)" "unprognostic (1.71e-1)" "unprognostic (9.88e-2)" GNB3 ENSG00000111664 "G protein subunit beta 3" P16520 12 6839954-6847393 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" Transducer "Congenital stationary night blindness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "retina: 396.1" "Group enriched" "Detected in many" 5 "Cone photoreceptor cells: 877.7;Retinal bipolar cells: 291.4;Rod photoreceptor cells: 222.9" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in some" 5 "Glioblastoma Multiforme (TCGA): 2.3;Testicular Germ Cell Tumor (TCGA): 8.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 16.7" "Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in some" "Region enhanced" "Detected in some" "cerebellum: 6.9" "HPA040736, HPA074924" Uncertain Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 42: Retina - Visual perception" "Cluster 48: Non-specific - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 16 "Plasma membrane" "Golgi apparatus" "HPA040736: , HPA074924: " "unprognostic (3.21e-2)" "unprognostic (5.50e-2)" "unprognostic (1.06e-1)" "unprognostic (2.05e-2)" "potential prognostic favorable (5.76e-5)" "unprognostic (2.59e-1)" "unprognostic (2.74e-2)" "unprognostic (1.12e-2)" "unprognostic (1.92e-2)" "unprognostic (2.01e-2)" "unprognostic (1.01e-1)" "unprognostic (1.01e-1)" "unprognostic (1.72e-1)" GNB4 ENSG00000114450 "G protein subunit beta 4" Q9HAV0 3 179396088-179451476 "Disease related genes, Human disease related genes, Predicted intracellular proteins, RAS pathway related proteins" Transducer "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Kupffer cells: 195.8;Macrophages: 142.8;Microglia: 429.8;Neutrophil progenitors: 164.6;Vascular endothelial cells: 129.4" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 543.3;committed oligodendrocyte precursor: 296.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018383, CAB018737, HPA040736, HPA074924" Supported Approved "Golgi apparatus,Plasma membrane" NA NA 970000 "Cluster 7: Non-specific - Innate immune response" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 22 "Plasma membrane" "Golgi apparatus" "CAB018383: , CAB018737: , HPA040736: , HPA074924: " "unprognostic (1.72e-1)" "unprognostic (2.22e-2)" "unprognostic (6.18e-2)" "unprognostic (1.11e-1)" "unprognostic (5.47e-3)" "unprognostic (1.63e-2)" "unprognostic (6.50e-2)" "unprognostic (1.26e-1)" "unprognostic (5.63e-2)" "unprognostic (2.98e-2)" "unprognostic (1.17e-1)" "unprognostic (1.16e-1)" "unprognostic (2.25e-2)" "unprognostic (1.54e-2)" "unprognostic (3.52e-2)" "unprognostic (1.48e-2)" "unprognostic (6.05e-3)" "unprognostic (2.71e-1)" "unprognostic (9.37e-2)" "unprognostic (9.85e-2)" "unprognostic (2.47e-2)" "unprognostic (1.07e-1)" "unprognostic (2.41e-1)" "unprognostic (7.70e-2)" "unprognostic (2.68e-1)" "unprognostic (1.62e-2)" "unprognostic (6.64e-2)" "unprognostic (1.98e-3)" "unprognostic (1.02e-1)" "unprognostic (2.89e-1)" "unprognostic (1.56e-1)" GNB5 GB5 ENSG00000069966 "G protein subunit beta 5" O14775 15 52115100-52191392 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" Transducer "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 111.3" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 380.9;Megakaryocytes: 241.1;Müller glia: 282.7;Platelets: 222.1;Retinal bipolar cells: 337.0;Rod photoreceptor cells: 539.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041942, HPA044198" Uncertain Approved "Nuclear speckles,Centrosome,Rods & Rings" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 19 "Nuclear speckles" "Centrosome, Rods & Rings" "HPA041942: , HPA044198: " "unprognostic (2.42e-3)" "unprognostic (1.40e-1)" "unprognostic (1.45e-1)" "unprognostic (2.63e-1)" "unprognostic (6.79e-2)" "unprognostic (5.13e-2)" "unprognostic (2.07e-2)" "unprognostic (1.91e-1)" "unprognostic (1.35e-2)" "unprognostic (4.33e-2)" "validated prognostic favorable (3.45e-7)" "validated prognostic favorable (1.97e-4)" "unprognostic (1.47e-3)" "unprognostic (7.83e-2)" "unprognostic (7.46e-2)" "unprognostic (2.92e-2)" "unprognostic (2.50e-1)" "unprognostic (1.45e-1)" "unprognostic (4.39e-1)" "unprognostic (5.76e-2)" "unprognostic (2.02e-1)" "unprognostic (3.67e-3)" "unprognostic (1.56e-1)" "unprognostic (2.10e-1)" "unprognostic (2.32e-1)" "potential prognostic favorable (7.08e-4)" "unprognostic (1.01e-1)" "unprognostic (3.37e-2)" "unprognostic (5.07e-3)" "unprognostic (9.02e-2)" "unprognostic (4.19e-2)" GNE "IBM2, Uae1" ENSG00000159921 "Glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase" Q9Y223 9 36214441-36277042 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Allosteric enzyme, Hydrolase, Kinase, Multifunctional enzyme, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "intestine: 45.4;liver: 84.6;salivary gland: 52.1" "Cell type enhanced" "Detected in many" "Epicardial cells: 113.7;Goblet cells: 138.7;Hepatocytes: 161.5;Salivary acinar cells: 141.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007045, HPA027258" Approved Supported Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 70: Intestinal goblet cells - Mucin production" 12 Cytosol "HPA007045: , HPA027258: " "unprognostic (2.59e-2)" "unprognostic (8.21e-3)" "unprognostic (2.83e-2)" "unprognostic (7.41e-2)" "unprognostic (3.82e-2)" "unprognostic (2.26e-1)" "unprognostic (1.22e-1)" "unprognostic (1.10e-1)" "unprognostic (3.87e-2)" "unprognostic (1.74e-2)" "validated prognostic favorable (2.57e-10)" "validated prognostic favorable (7.78e-6)" "unprognostic (1.12e-3)" "unprognostic (7.89e-3)" "unprognostic (3.90e-2)" "unprognostic (1.34e-1)" "unprognostic (8.79e-2)" "unprognostic (1.19e-1)" "unprognostic (7.08e-2)" "unprognostic (2.91e-2)" "unprognostic (1.50e-1)" "unprognostic (3.62e-3)" "unprognostic (8.49e-2)" "unprognostic (6.73e-2)" "unprognostic (1.59e-1)" "unprognostic (7.20e-3)" "unprognostic (1.16e-1)" "unprognostic (2.79e-1)" "unprognostic (1.10e-1)" "unprognostic (5.92e-2)" "unprognostic (1.44e-1)" GNG10 ENSG00000242616 "G protein subunit gamma 10" P50151 9 111661605-111670226 "Predicted intracellular proteins, RAS pathway related proteins" Transducer "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 11.2;Bergmann glia: 13.3;Brain excitatory neurons: 17.8;Brain inhibitory neurons: 13.8;Choroid plexus epithelial cells: 12.7;Ependymal cells: 11.1;Microglia: 26.0;Neutrophils: 5.3;Oligodendrocyte progenitor cells: 17.7;Oligodendrocytes: 19.6;Other brain neurons: 20.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 6 "neutrophil: 515.3" "Lineage enriched" "Detected in all" 9 "granulocytes: 515.3" "Low cancer specificity" "Detected in all" "Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 36: Brain & Liver - Signaling" "Cluster 21: Non-specific - Metabolism" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 98: Neurons - Neurotransmission & signaling" 35 "unprognostic (5.94e-2)" "unprognostic (2.20e-1)" "unprognostic (1.26e-1)" "unprognostic (2.23e-3)" "unprognostic (2.15e-2)" "unprognostic (1.56e-1)" "unprognostic (2.69e-2)" "unprognostic (7.01e-2)" "potential prognostic unfavorable (1.32e-5)" "unprognostic (1.21e-1)" "potential prognostic favorable (2.60e-4)" "unprognostic (9.03e-2)" "unprognostic (1.04e-3)" "unprognostic (1.42e-1)" "unprognostic (7.34e-3)" "unprognostic (2.72e-2)" "unprognostic (1.61e-2)" "unprognostic (5.58e-2)" "unprognostic (6.83e-2)" "unprognostic (3.74e-2)" "unprognostic (4.82e-2)" "unprognostic (2.18e-1)" "unprognostic (4.02e-2)" "unprognostic (2.62e-1)" "unprognostic (7.05e-2)" "unprognostic (9.37e-2)" "unprognostic (1.58e-1)" "unprognostic (7.48e-2)" "unprognostic (1.39e-1)" "unprognostic (6.47e-2)" "unprognostic (5.89e-2)" GNG11 GNGT11 ENSG00000127920 "G protein subunit gamma 11" P61952 7 93921735-93928610 "Predicted intracellular proteins, RAS pathway related proteins" Transducer "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Platelets: 6640.8" "Cell type enhanced" "Detected in some" "endothelial cell: 203.7;fibroblast: 90.9;pericyte: 271.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 20.5;neutrophil: 9.8" "Lineage enriched" "Detected in many" 5 "granulocytes: 20.5" "Cancer enhanced" "Detected in many" "Kidney cancer: 86.2" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045255 Uncertain NA NA 1000000 "Cluster 35: Neutrophils - Protein binding" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 3 "HPA045255: " "unprognostic (3.81e-1)" "unprognostic (1.51e-1)" "unprognostic (3.20e-1)" "unprognostic (9.00e-2)" "unprognostic (6.71e-2)" "unprognostic (4.16e-1)" "unprognostic (1.60e-2)" "unprognostic (1.43e-3)" "unprognostic (8.40e-2)" "unprognostic (3.63e-2)" "unprognostic (1.04e-3)" "unprognostic (1.11e-1)" "potential prognostic unfavorable (2.33e-4)" "unprognostic (1.61e-2)" "unprognostic (1.61e-2)" "unprognostic (3.87e-2)" "unprognostic (9.83e-2)" "unprognostic (2.43e-3)" "unprognostic (4.99e-2)" "unprognostic (1.63e-1)" "unprognostic (4.12e-2)" "unprognostic (1.33e-1)" "unprognostic (2.92e-1)" "unprognostic (8.21e-2)" "unprognostic (1.02e-1)" "unprognostic (2.20e-1)" "unprognostic (1.82e-2)" "potential prognostic unfavorable (6.08e-4)" "unprognostic (3.15e-1)" "unprognostic (1.60e-1)" "unprognostic (1.33e-1)" GNG12 ENSG00000172380 "G protein subunit gamma 12" Q9UBI6 1 67701475-67833467 "Predicted intracellular proteins, RAS pathway related proteins" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Enterocytes: 386.0;Esophageal apical cells: 641.3" "Cell type enhanced" "Detected in many" "ependymal cell: 176.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skin - Keratinocyte (other), Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057790, HPA062208" Enhanced Supported Approved Mitochondria NA NA 170000 "Cluster 77: Intestine - Digestion" "Cluster 39: Astrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 13 Mitochondria "HPA057790: , HPA062208: " "unprognostic (2.16e-2)" "unprognostic (1.00e-1)" "unprognostic (2.82e-1)" "unprognostic (1.46e-3)" "unprognostic (9.23e-3)" "unprognostic (1.66e-1)" "unprognostic (1.74e-1)" "unprognostic (3.56e-3)" "unprognostic (6.93e-2)" "unprognostic (7.09e-3)" "potential prognostic favorable (4.75e-10)" "unprognostic (1.09e-1)" "unprognostic (1.80e-1)" "unprognostic (3.30e-2)" "unprognostic (1.62e-1)" "unprognostic (5.37e-3)" "unprognostic (2.46e-2)" "unprognostic (3.18e-2)" "potential prognostic unfavorable (2.19e-5)" "unprognostic (5.17e-2)" "unprognostic (3.10e-3)" "unprognostic (6.67e-3)" "unprognostic (3.22e-2)" "unprognostic (1.22e-1)" "unprognostic (6.44e-2)" "unprognostic (1.89e-2)" "unprognostic (5.34e-2)" "unprognostic (3.53e-2)" "unprognostic (2.11e-1)" "unprognostic (6.35e-2)" "unprognostic (4.56e-1)" GNG13 "G(gamma)13, h2-35" ENSG00000127588 "G protein subunit gamma 13" Q9P2W3 16 798041-800734 "Predicted intracellular proteins, RAS pathway related proteins" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 42 "brain: 58.3;retina: 51.9" "Group enriched" "Detected in some" 16 "Retinal bipolar cells: 165.9;Tuft cells: 265.1" "Cell type enhanced" "Detected in some" "Bergmann glia: 3.5;thalamic excitatory: 4.1" "Cancer enhanced" "Detected in some" "Breast Invasive Carcinoma (TCGA): 2.1" "Group enriched" "Detected in many" 6 "cerebellum: 112.2;thalamus: 57.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "cerebellum: 940.1" "Group enriched" "Detected in many" 5 "cerebellum: 27.0;olfactory bulb: 9.1" HPA046272 Enhanced NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 15: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 24 "HPA046272: " "unprognostic (1.71e-1)" "unprognostic (8.63e-2)" "unprognostic (8.65e-2)" "unprognostic (7.09e-2)" GNG14 ENSG00000283980 "G protein subunit gamma 14" A0A1W2PPG7 19 12687998-12688422 "Predicted intracellular proteins" Transducer "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 9 "Late spermatids: 6.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" NA NA "Cluster 17: Choroid plexus - Cilium" "Cluster 56: Non-specific - Sensory perception" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" "unprognostic (4.35e-3)" "unprognostic (2.23e-1)" GNG2 ENSG00000186469 "G protein subunit gamma 2" P59768 14 51826195-51979342 "Predicted intracellular proteins, RAS pathway related proteins" "Host-virus interaction" Transducer "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 80.6;testis: 107.0" "Cell type enhanced" "Detected in many" "Early spermatids: 981.4;Kupffer cells: 359.7;Late spermatids: 1785.1;Neutrophil progenitors: 429.6;Neutrophils: 2004.4;NK-cells: 1112.2;Sertoli cells: 447.0;T-cells: 720.8" "Cell type enhanced" "Detected in all" "leukocyte: 713.1" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 56.3;Skin Cutaneous Melanoma (TCGA): 53.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Neuroblastoma: 73.1;skin cancer: 53.0" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Colon - Enteric glia cells, Pituitary gland - Thyrotropes, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003534, CAB018380" Uncertain Supported Approved "Vesicles,Plasma membrane" NA NA 56000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 14: Neurons - Synaptic function" "Cluster 69: Skin cancer - ECM organization" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 43 "Plasma membrane" Vesicles "CAB018380: , HPA003534: " "unprognostic (4.32e-2)" "unprognostic (5.84e-2)" "unprognostic (2.22e-1)" "unprognostic (1.17e-1)" "unprognostic (9.41e-2)" "unprognostic (5.14e-2)" "unprognostic (2.81e-1)" "unprognostic (3.67e-3)" "unprognostic (1.14e-1)" "unprognostic (7.01e-2)" "potential prognostic favorable (6.46e-4)" "unprognostic (1.20e-2)" "unprognostic (2.34e-3)" "unprognostic (1.61e-1)" "unprognostic (7.93e-2)" "unprognostic (8.08e-3)" "unprognostic (8.51e-2)" "unprognostic (1.05e-1)" "unprognostic (3.04e-3)" "unprognostic (7.16e-2)" "unprognostic (1.80e-1)" "potential prognostic favorable (3.69e-4)" "unprognostic (5.19e-2)" "unprognostic (6.62e-2)" "unprognostic (5.83e-2)" "unprognostic (6.44e-2)" "unprognostic (1.13e-2)" "unprognostic (4.54e-2)" "unprognostic (1.44e-1)" "unprognostic (1.39e-1)" "unprognostic (1.50e-1)" GNG3 ENSG00000162188 "G protein subunit gamma 3" P63215 11 62707676-62709201 "Predicted intracellular proteins, RAS pathway related proteins" Transducer "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "brain: 465.1" "Cell type enriched" "Detected in some" 4 "Late spermatids: 247.6" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in some" 16 "Glioblastoma Multiforme (TCGA): 33.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 30 "memory B-cell: 17.0;naive B-cell: 17.2" "Lineage enriched" "Detected in single" 31 "B-cells: 17.2" "Cancer enriched" "Detected in many" 9 "Neuroblastoma: 48.8" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pituitary gland - Lactotropes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 98: Neurons - Neurotransmission & signaling" 7 "unprognostic (9.02e-2)" "unprognostic (9.70e-3)" "unprognostic (6.82e-2)" "unprognostic (2.16e-2)" "unprognostic (2.43e-1)" "unprognostic (6.50e-2)" "unprognostic (1.44e-1)" "unprognostic (1.14e-3)" "unprognostic (2.84e-1)" "unprognostic (8.38e-2)" "unprognostic (3.75e-2)" GNG4 ENSG00000168243 "G protein subunit gamma 4" P50150 1 235547685-235650754 "Predicted intracellular proteins, RAS pathway related proteins" Transducer "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.5;ovary: 30.6;pituitary gland: 29.7" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 53.2;Brain inhibitory neurons: 49.3;Gonadotrophs: 91.5;Lactotrophs: 175.0;Neuroendocrine cells: 90.8;Oocytes: 59.9;Other brain neurons: 59.3;Ovarian stromal cells: 51.1;Pancreatic islet cells: 90.3;Paneth cells: 58.0;Prostatic glandular cells: 98.2;Somatotrophs: 156.2" "Cell type enhanced" "Detected in many" "LAMP5-LHX6 and Chandelier: 178.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 122.0" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Minor Salivary Gland - Minor salivary gland basal cells, Pancreas - Alpha cells, Pancreas - Beta cells, Pituitary gland - Lactotropes, Prostate - Prostate glandular cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Stomach - Gastric enteroendocrine cells, Testis - Spermatogonia" "Region enriched" "Detected in all" 6 "olfactory bulb: 469.4" "Region enhanced" "Detected in all" "olfactory bulb: 223.6" NA NA "Cluster 65: Brain - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 6 "unprognostic (8.79e-2)" "unprognostic (5.19e-3)" "unprognostic (9.07e-2)" "unprognostic (7.58e-2)" "unprognostic (1.55e-2)" "unprognostic (1.24e-1)" "unprognostic (6.86e-2)" "unprognostic (5.78e-3)" "unprognostic (4.45e-2)" "potential prognostic unfavorable (4.47e-4)" "unprognostic (1.09e-1)" "unprognostic (1.01e-2)" "unprognostic (1.67e-2)" "unprognostic (1.25e-2)" "unprognostic (7.27e-3)" "unprognostic (2.13e-1)" "unprognostic (1.17e-1)" "unprognostic (1.13e-1)" "unprognostic (3.97e-1)" "unprognostic (1.48e-1)" "unprognostic (5.56e-3)" "unprognostic (1.12e-2)" "unprognostic (6.49e-2)" "unprognostic (2.53e-1)" "unprognostic (1.90e-2)" "unprognostic (5.71e-2)" "unprognostic (8.23e-2)" "unprognostic (1.54e-1)" "unprognostic (1.29e-1)" GNG5 ENSG00000174021 "G protein subunit gamma 5" P63218 1 84498323-84506581 "Predicted intracellular proteins, RAS pathway related proteins" Transducer "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 334.1;Early spermatids: 275.4;Enteric transient amplifying cells: 256.7;Enterocytes: 314.0;Late primary spermatocytes: 243.9;Parietal cells: 385.4" "Cell type enhanced" "Detected in many" "endothelial cell: 110.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "CAB032623, HPA043651" Approved NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 8: Immune cells - Immune response" "Cluster 37: Non-specific - mRNA processing" "Cluster 15: Non-specific - Protein processing" 36 "CAB032623: , HPA043651: " "unprognostic (1.33e-1)" "unprognostic (1.18e-1)" "unprognostic (4.72e-1)" "unprognostic (6.26e-2)" "unprognostic (1.22e-3)" "unprognostic (1.75e-1)" "unprognostic (9.76e-3)" "unprognostic (4.94e-2)" "unprognostic (1.25e-1)" "unprognostic (8.07e-2)" "unprognostic (4.01e-2)" "unprognostic (4.09e-2)" "unprognostic (6.01e-2)" "potential prognostic unfavorable (5.82e-7)" "unprognostic (1.06e-2)" "unprognostic (1.76e-2)" "unprognostic (4.66e-3)" "unprognostic (7.17e-2)" "unprognostic (7.67e-2)" "unprognostic (4.31e-3)" "unprognostic (7.78e-2)" "unprognostic (2.16e-3)" "unprognostic (9.73e-3)" "unprognostic (9.40e-2)" "unprognostic (9.88e-2)" "unprognostic (2.13e-1)" "unprognostic (3.13e-3)" "unprognostic (2.19e-2)" "unprognostic (8.80e-2)" "unprognostic (1.32e-2)" "unprognostic (7.09e-2)" GNG5B GNG5P2 ENSG00000133136 "G protein subunit gamma 5B" X 110346103-110440372 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Tissue enhanced" "Detected in some" "choroid plexus: 1.5;liver: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in many" 6 "choroid plexus: 18.0" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA043651 Uncertain NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "HPA043651: " GNG7 FLJ00058 ENSG00000176533 "G protein subunit gamma 7" O60262 19 2511219-2702694 "Predicted intracellular proteins, RAS pathway related proteins" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 17 "brain: 421.2" "Cell type enhanced" "Detected in many" "B-cells: 766.8;Microglia: 327.5;Oligodendrocytes: 337.8;pDCs: 324.8;Plasma cells: 789.3;Retinal horizontal cells: 368.6;Sertoli cells: 321.9;Somatotrophs: 351.7" "Cell type enhanced" "Detected in all" "medium spiny neuron: 595.4;oligodendrocyte: 489.6" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 37.3;Skin Cutaneous Melanoma (TCGA): 34.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 57.5;naive B-cell: 50.3;plasmacytoid DC: 48.1" "Group enriched" "Detected in many" 4 "B-cells: 57.5;dendritic cells: 48.1" "Group enriched" "Detected in many" 7 "Leukemia: 15.0;lymphoma: 21.3;Myeloma: 28.9;skin cancer: 9.6" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Skin - Eccrine sweat gland cells, Spleen - B-cells (Spleen), Testis - Sertoli cells" "Region enriched" "Detected in all" 6 "basal ganglia: 1271.4" "Region enriched" "Detected in all" 5 "basal ganglia: 493.7" HPA057790 Supported Supported NA NA 11000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 9 "HPA057790: " "unprognostic (9.06e-3)" "unprognostic (3.97e-3)" "potential prognostic favorable (5.84e-4)" "unprognostic (2.16e-1)" "unprognostic (1.75e-1)" "unprognostic (3.13e-1)" "unprognostic (3.53e-2)" "unprognostic (3.74e-2)" "validated prognostic favorable (1.28e-9)" "validated prognostic favorable (2.06e-4)" "potential prognostic favorable (2.88e-4)" "validated prognostic favorable (3.68e-4)" "validated prognostic favorable (7.36e-6)" "potential prognostic favorable (3.60e-6)" "unprognostic (1.62e-2)" "unprognostic (1.07e-1)" "unprognostic (2.17e-1)" "unprognostic (1.41e-2)" "unprognostic (4.95e-2)" "potential prognostic favorable (1.20e-4)" "unprognostic (9.72e-2)" "unprognostic (3.64e-1)" "unprognostic (4.24e-1)" "unprognostic (7.81e-2)" "unprognostic (1.83e-1)" "unprognostic (1.80e-1)" "unprognostic (2.85e-2)" "unprognostic (1.60e-1)" GNG8 ENSG00000167414 "G protein subunit gamma 8" Q9UK08 19 46633953-46636541 "Predicted intracellular proteins, RAS pathway related proteins" Transducer "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 9.4;heart muscle: 5.0" "Group enriched" "Detected in some" 12 "Megakaryocytes: 92.7;Platelets: 191.5" "Cell type enhanced" "Detected in some" "oligodendrocyte: 4.7" "Cancer enriched" "Detected in many" 4 "Bladder Urothelial Carcinoma (TCGA): 45.1" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "naive B-cell: 5.4;T-reg: 3.2" "Group enriched" "Detected in many" 4 "B-cells: 5.4;T-cells: 3.2" "Cancer enriched" "Detected in some" 8 "Neuroblastoma: 54.4" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal medulla cells, Pituitary gland - Gonadotropes, Stomach - Fibroblasts" "Region enhanced" "Detected in all" "white matter: 20.2" "Low region specificity" "Detected in all" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 35: Non-specific - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 47: Platelets - Hemostasis" 3 "unprognostic (7.22e-2)" "unprognostic (3.50e-3)" "unprognostic (1.24e-3)" "unprognostic (6.50e-2)" "unprognostic (3.39e-1)" "unprognostic (5.67e-2)" "unprognostic (4.58e-2)" "potential prognostic favorable (9.39e-5)" "unprognostic (1.10e-3)" "unprognostic (1.73e-1)" "unprognostic (1.63e-1)" "unprognostic (1.75e-1)" "unprognostic (4.52e-2)" "unprognostic (2.65e-1)" "unprognostic (4.39e-2)" "unprognostic (1.44e-1)" "unprognostic (2.60e-1)" "unprognostic (2.21e-1)" "unprognostic (6.02e-2)" "unprognostic (4.81e-2)" "unprognostic (6.88e-2)" "unprognostic (5.85e-2)" "unprognostic (6.22e-2)" "unprognostic (2.24e-1)" GNGT1 GNG1 ENSG00000127928 "G protein subunit gamma transducin 1" P63211 7 93591573-93911265 "Predicted intracellular proteins, RAS pathway related proteins" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 162 "retina: 1760.3" "Cell type enriched" "Detected in many" 7 "Rod photoreceptor cells: 1546.9" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 4.1;endothelial cell: 4.1;fibroblast: 6.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 7.6" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA042721 Enhanced NA NA "Cluster 42: Retina - Visual perception" "Cluster 48: Non-specific - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 79: Photoreceptor cells - Phototransduction" 12 "HPA042721: " "unprognostic (9.84e-3)" "unprognostic (6.08e-3)" "unprognostic (4.92e-2)" "unprognostic (2.00e-1)" "unprognostic (2.94e-2)" "unprognostic (1.17e-1)" "unprognostic (5.98e-2)" "unprognostic (1.13e-1)" "unprognostic (1.18e-2)" "unprognostic (6.36e-2)" "unprognostic (4.42e-2)" "unprognostic (1.35e-1)" "unprognostic (7.39e-2)" "unprognostic (8.14e-2)" "unprognostic (1.16e-2)" "unprognostic (2.08e-2)" "unprognostic (2.11e-2)" GNGT2 GNG9 ENSG00000167083 "G protein subunit gamma transducin 2" O14610 17 49202791-49210574 "Predicted intracellular proteins, RAS pathway related proteins, Transporters" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "retina: 145.5" "Cell type enriched" "Detected in some" 10 "Cone photoreceptor cells: 385.0" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 3.2;leukocyte: 6.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 67.1" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "lymphoma: 25.5" "Adrenal gland - Macrophages, Spleen - Macrophages" "Low region specificity" "Detected in all" HPA043381 Enhanced NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 42: Retina - Visual perception" "Cluster 49: Hindbrain - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 79: Photoreceptor cells - Phototransduction" 2 "HPA043381: " "unprognostic (1.93e-1)" "unprognostic (1.17e-1)" "unprognostic (1.53e-1)" "unprognostic (2.45e-3)" "unprognostic (3.38e-2)" "unprognostic (2.57e-1)" "unprognostic (7.65e-2)" "unprognostic (2.42e-1)" "unprognostic (2.39e-3)" "unprognostic (1.53e-1)" "potential prognostic favorable (3.30e-4)" "unprognostic (7.70e-3)" "unprognostic (2.65e-1)" "unprognostic (2.82e-1)" "unprognostic (5.81e-2)" "unprognostic (1.63e-2)" "unprognostic (5.00e-2)" "unprognostic (1.82e-1)" "unprognostic (2.07e-1)" "unprognostic (4.29e-2)" "unprognostic (3.72e-1)" "unprognostic (1.86e-1)" "unprognostic (7.28e-2)" "unprognostic (9.89e-2)" "unprognostic (8.76e-2)" "unprognostic (3.01e-1)" "unprognostic (1.87e-1)" "unprognostic (2.37e-1)" "unprognostic (3.98e-2)" "unprognostic (2.34e-1)" "unprognostic (1.97e-1)" GNL1 HSR1 ENSG00000204590 "G protein nucleolar 1 (putative)" P36915 6 30541381-30556489 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 39.6;Early spermatids: 45.2;Late primary spermatocytes: 63.0;Late spermatids: 125.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033575, HPA043338, HPA050455" Uncertain Supported Vesicles NA NA 5500 "Cluster 1: T-cells - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 28: Non-specific - Nuclear processes" "Cluster 102: Non-specific - Mixed function" 3 Vesicles "CAB033575: , HPA043338: , HPA050455: " "unprognostic (2.65e-1)" "unprognostic (2.67e-2)" "unprognostic (1.85e-1)" "unprognostic (2.89e-2)" "unprognostic (1.81e-1)" "unprognostic (3.84e-2)" "unprognostic (1.85e-2)" "unprognostic (5.00e-2)" "unprognostic (2.42e-1)" "unprognostic (6.72e-2)" "potential prognostic favorable (3.32e-4)" "unprognostic (2.21e-1)" "unprognostic (2.61e-1)" "unprognostic (3.60e-2)" "unprognostic (1.67e-2)" "unprognostic (1.84e-1)" "unprognostic (8.78e-2)" "unprognostic (2.12e-2)" "unprognostic (3.03e-1)" "unprognostic (1.47e-2)" "unprognostic (1.64e-1)" "unprognostic (4.74e-2)" "unprognostic (5.52e-3)" "unprognostic (3.85e-1)" "unprognostic (2.53e-1)" "unprognostic (2.05e-1)" "unprognostic (2.22e-2)" "unprognostic (2.85e-1)" "unprognostic (1.98e-1)" "unprognostic (1.41e-1)" "unprognostic (2.75e-1)" GNL2 "HUMAUANTIG, Ngp-1, Nog2, Nug2" ENSG00000134697 "G protein nucleolar 2" Q13823 1 37566816-37595937 "Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 152.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027163, HPA060026" Approved Supported "Nucleoli,Nucleoli rim" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 37: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 113 "Nucleoli, Nucleoli rim" "HPA027163: , HPA060026: " "unprognostic (2.15e-1)" "unprognostic (8.71e-2)" "unprognostic (5.80e-2)" "unprognostic (4.88e-2)" "unprognostic (1.34e-2)" "unprognostic (1.71e-1)" "unprognostic (2.73e-1)" "unprognostic (2.48e-2)" "unprognostic (2.56e-2)" "unprognostic (9.52e-3)" "unprognostic (3.40e-2)" "unprognostic (3.26e-1)" "unprognostic (3.98e-3)" "validated prognostic unfavorable (2.47e-12)" "validated prognostic unfavorable (3.42e-5)" "unprognostic (1.80e-1)" "potential prognostic unfavorable (3.51e-4)" "unprognostic (1.32e-1)" "unprognostic (1.23e-1)" "unprognostic (1.48e-2)" "unprognostic (3.32e-1)" "potential prognostic unfavorable (3.12e-4)" "unprognostic (9.01e-2)" "unprognostic (1.87e-2)" "unprognostic (1.60e-1)" "unprognostic (1.90e-1)" "unprognostic (9.00e-2)" "unprognostic (2.65e-1)" "unprognostic (2.54e-2)" "unprognostic (1.31e-1)" "unprognostic (1.27e-1)" GNL3 "C77032, E2IG3, MGC800, NS" ENSG00000163938 "G protein nucleolar 3" Q9BVP2 3 52681156-52694497 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 382.8;Prostatic club cells: 248.7;Urothelial cells: 281.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020770, HPA036742, HPA036743" Enhanced Enhanced "Nucleoli rim,Nuclear bodies,Mitotic chromosome" Yes No "Cluster 30: Non-specific - DNA binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 69: Urothelial cells - Basic cellular functions" 97 "Nucleoli rim" "Nuclear bodies, Mitotic chromosome" "CAB020770: , HPA036742: , HPA036743: " "unprognostic (7.45e-2)" "unprognostic (6.93e-2)" "unprognostic (1.69e-1)" "unprognostic (1.74e-1)" "unprognostic (8.96e-3)" "unprognostic (2.55e-1)" "unprognostic (1.52e-1)" "unprognostic (1.28e-1)" "unprognostic (7.17e-2)" "unprognostic (1.02e-2)" "unprognostic (3.71e-2)" "unprognostic (1.03e-1)" "unprognostic (2.88e-3)" "validated prognostic unfavorable (7.31e-6)" "validated prognostic unfavorable (2.81e-4)" "unprognostic (1.96e-2)" "potential prognostic unfavorable (7.80e-7)" "unprognostic (1.14e-2)" "unprognostic (9.19e-2)" "unprognostic (8.80e-3)" "unprognostic (3.50e-1)" "unprognostic (1.22e-2)" "unprognostic (2.29e-2)" "unprognostic (1.67e-3)" "unprognostic (5.28e-3)" "unprognostic (3.49e-1)" "unprognostic (1.95e-2)" "unprognostic (1.34e-1)" "unprognostic (3.81e-1)" "unprognostic (3.52e-3)" "unprognostic (1.63e-2)" GNL3L "FLJ10613, GNL3B" ENSG00000130119 "G protein nucleolar 3 like" Q9NVN8 X 54530183-54621521 "Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036314, HPA036315" Supported Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 22 Nucleoli "Nucleoplasm, Cytosol" "HPA036314: , HPA036315: " "unprognostic (7.74e-2)" "unprognostic (2.08e-2)" "unprognostic (1.44e-1)" "unprognostic (1.13e-2)" "unprognostic (1.89e-1)" "unprognostic (2.69e-1)" "unprognostic (2.18e-2)" "unprognostic (3.17e-2)" "unprognostic (2.06e-1)" "unprognostic (1.76e-3)" "potential prognostic favorable (4.07e-4)" "unprognostic (6.27e-2)" "unprognostic (1.44e-1)" "unprognostic (8.79e-3)" "unprognostic (1.22e-1)" "unprognostic (1.40e-1)" "unprognostic (1.94e-3)" "unprognostic (1.23e-1)" "unprognostic (6.30e-2)" "unprognostic (2.01e-1)" "unprognostic (4.17e-2)" "unprognostic (3.03e-2)" "unprognostic (1.60e-1)" "unprognostic (4.43e-2)" "unprognostic (1.60e-2)" "unprognostic (7.42e-2)" "unprognostic (1.31e-1)" "unprognostic (1.47e-2)" "unprognostic (4.53e-1)" "unprognostic (8.73e-3)" "unprognostic (1.26e-1)" GNLY "D2S69E, LAG-2, LAG2, NKG5, TLA519" ENSG00000115523 Granulysin P22749 2 85685175-85698852 "Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial, Fungicide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 271.5;endometrium 1: 67.6;lymphoid tissue: 81.2" "Cell type enriched" "Detected in many" 6 "NK-cells: 3025.1" "Cell type enriched" "Detected in some" 15 "leukocyte: 659.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "NK-cell: 17662.2" "Group enriched" "Detected in all" 63 "NK-cells: 17662.2;T-cells: 7897.0" "Group enriched" "Detected in some" 7 "Leukemia: 3.8;lymphoma: 12.1" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Thyroid gland - T-cells" "Low region specificity" "Detected in many" "CAB025186, HPA058021" Enhanced "Secreted to blood" Defense NA NA 2920000 17000 "Cluster 15: NK-cells - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 2 "CAB025186: , HPA058021: " "unprognostic (1.43e-2)" "unprognostic (4.16e-2)" "unprognostic (3.38e-2)" "unprognostic (2.18e-2)" "unprognostic (3.93e-1)" "unprognostic (2.03e-1)" "unprognostic (2.88e-2)" "unprognostic (1.36e-2)" "unprognostic (1.29e-1)" "unprognostic (2.03e-1)" "unprognostic (5.59e-2)" "unprognostic (1.57e-1)" "unprognostic (4.59e-2)" "unprognostic (1.39e-1)" "unprognostic (3.07e-2)" "unprognostic (1.21e-1)" "unprognostic (1.86e-1)" "unprognostic (2.25e-1)" "unprognostic (1.22e-1)" "unprognostic (9.71e-2)" "unprognostic (1.51e-1)" "unprognostic (3.83e-2)" "unprognostic (7.90e-2)" "unprognostic (2.81e-1)" "unprognostic (8.84e-2)" "unprognostic (2.21e-1)" "potential prognostic favorable (4.02e-4)" "unprognostic (6.94e-2)" "unprognostic (2.54e-1)" "unprognostic (1.79e-1)" "unprognostic (1.35e-1)" GNMT ENSG00000124713 "Glycine N-methyltransferase" Q14749 6 42960754-42963880 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Methyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "liver: 278.9;pancreas: 563.6" "Cell type enriched" "Detected in many" 6 "Hepatocytes: 1065.6" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 19 "Liver Hepatocellular Carcinoma (TCGA): 95.4;Prostate Adenocarcinoma (TCGA): 74.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 8.8" "Breast - Breast glandular cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells" "Region enriched" "Detected in some" 4 "cerebellum: 15.7" "Low region specificity" "Detected in all" HPA027501 Enhanced Supported Cytosol NA NA 230000 "Cluster 70: Non-specific - Protein processing" "Cluster 15: Non-specific - Transcription" "Cluster 60: Prostate cancer - Unknown function" "Cluster 93: Hepatocytes - Bile production & excretion" 15 Cytosol "HPA027501: " "unprognostic (6.15e-2)" "unprognostic (2.43e-1)" "unprognostic (2.70e-2)" "potential prognostic favorable (8.24e-4)" "unprognostic (7.46e-2)" "validated prognostic favorable (2.63e-4)" "validated prognostic favorable (4.01e-4)" "potential prognostic favorable (1.56e-6)" "potential prognostic favorable (7.82e-4)" "unprognostic (1.20e-1)" "unprognostic (1.70e-1)" "unprognostic (3.70e-2)" "unprognostic (9.46e-2)" GNPAT "DAP-AT, DAPAT, DHAPAT" ENSG00000116906 "Glyceronephosphate O-acyltransferase" O15228 1 231241207-231277973 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Acyltransferase, Transferase" "Cataract, Disease variant, Dwarfism, Rhizomelic chondrodysplasia punctata" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 214.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039130 Approved "Vesicles,Cell Junctions" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 8 "Vesicles, Cell Junctions" "HPA039130: " "unprognostic (1.34e-1)" "unprognostic (1.41e-1)" "unprognostic (3.97e-1)" "unprognostic (2.02e-2)" "unprognostic (1.61e-2)" "unprognostic (1.84e-2)" "unprognostic (9.82e-2)" "unprognostic (1.56e-2)" "unprognostic (1.57e-1)" "unprognostic (7.78e-3)" "potential prognostic favorable (5.37e-4)" "unprognostic (9.73e-2)" "potential prognostic unfavorable (8.34e-4)" "unprognostic (2.33e-2)" "unprognostic (5.47e-2)" "unprognostic (5.91e-2)" "unprognostic (5.33e-2)" "unprognostic (2.26e-1)" "unprognostic (2.34e-1)" "unprognostic (1.32e-1)" "unprognostic (6.94e-2)" "unprognostic (2.28e-2)" "unprognostic (9.95e-2)" "unprognostic (3.56e-1)" "potential prognostic unfavorable (5.87e-4)" "unprognostic (3.34e-3)" "unprognostic (8.54e-2)" "unprognostic (2.36e-1)" "unprognostic (6.51e-2)" "unprognostic (7.02e-3)" "unprognostic (2.30e-1)" GNPDA1 "GNPDA, GNPI, GPI, HLN, KIAA0060" ENSG00000113552 "Glucosamine-6-phosphate deaminase 1" P46926 5 141991749-142013041 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" "Hydrolase, Isomerase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 203.3;Kupffer cells: 103.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Lung - Macrophages, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000499, HPA046891" Uncertain Approved "Golgi apparatus,Vesicles" NA NA 670000 "Cluster 33: Non-specific - ATP binding" "Cluster 72: Kidney - Transmembrane transport" "Cluster 21: Non-specific - Metabolism" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 6 Vesicles "Golgi apparatus" "HPA000499: , HPA046891: " "unprognostic (2.78e-1)" "unprognostic (5.00e-2)" "unprognostic (1.74e-1)" "unprognostic (1.76e-1)" "unprognostic (4.30e-1)" "unprognostic (8.42e-2)" "unprognostic (2.18e-1)" "unprognostic (1.51e-2)" "unprognostic (1.23e-2)" "unprognostic (1.17e-2)" "potential prognostic favorable (5.43e-6)" "unprognostic (4.72e-1)" "unprognostic (4.07e-3)" "potential prognostic unfavorable (8.41e-6)" "unprognostic (1.80e-2)" "unprognostic (1.48e-1)" "unprognostic (2.54e-1)" "unprognostic (7.73e-2)" "unprognostic (2.30e-1)" "unprognostic (1.44e-1)" "unprognostic (1.36e-1)" "unprognostic (1.52e-1)" "unprognostic (2.48e-1)" "unprognostic (1.09e-1)" "unprognostic (3.83e-2)" "unprognostic (1.61e-2)" "unprognostic (6.19e-2)" "unprognostic (2.03e-1)" "unprognostic (1.02e-1)" "unprognostic (7.50e-2)" "unprognostic (7.23e-2)" GNPDA2 SB52 ENSG00000163281 "Glucosamine-6-phosphate deaminase 2" Q8TDQ7 4 44682200-44726588 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" "Hydrolase, Isomerase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 130.6;Epicardial cells: 86.4;Oocytes: 234.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000499, HPA046891" Uncertain Approved "Golgi apparatus,Vesicles" NA NA 640000 "Cluster 1: T-cells - Unknown function" "Cluster 65: Brain - Transcription" "Cluster 2: Neurons - Nucleosome" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 7 Vesicles "Golgi apparatus" "HPA000499: , HPA046891: " "potential prognostic favorable (7.72e-4)" "unprognostic (8.42e-2)" "unprognostic (2.08e-1)" "unprognostic (3.48e-1)" "unprognostic (1.27e-1)" "unprognostic (8.55e-2)" "unprognostic (3.45e-1)" "unprognostic (2.68e-3)" "unprognostic (2.87e-1)" "unprognostic (7.49e-2)" "validated prognostic favorable (8.64e-7)" "validated prognostic favorable (1.55e-4)" "unprognostic (4.80e-2)" "unprognostic (1.99e-3)" "unprognostic (1.25e-1)" "unprognostic (4.23e-2)" "unprognostic (3.07e-1)" "unprognostic (1.34e-1)" "unprognostic (8.40e-2)" "unprognostic (6.19e-2)" "unprognostic (4.69e-2)" "unprognostic (7.45e-2)" "unprognostic (2.77e-1)" "unprognostic (1.04e-1)" "unprognostic (1.17e-1)" "unprognostic (3.06e-1)" "unprognostic (1.40e-1)" "unprognostic (2.45e-2)" "unprognostic (8.07e-2)" "unprognostic (2.05e-3)" "unprognostic (1.92e-1)" GNPNAT1 "FLJ10607, Gpnat1" ENSG00000100522 "Glucosamine-phosphate N-acetyltransferase 1" Q96EK6 14 52775193-52791668 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Acyltransferase, Transferase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 72.1" "Cell type enhanced" "Detected in many" "Epididymal clear cells: 110.2;Extravillous trophoblasts: 90.2;Hepatocytes: 126.2;Late primary spermatocytes: 128.5;Pancreatic acinar cells: 94.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Prostate - Prostate glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044647 Approved NA NA 220000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 31: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 70: Intestinal goblet cells - Mucin production" 1 "HPA044647: " "unprognostic (9.45e-2)" "unprognostic (5.52e-3)" "unprognostic (4.47e-3)" "unprognostic (2.42e-2)" "unprognostic (3.99e-3)" "unprognostic (4.65e-2)" "unprognostic (2.36e-1)" "potential prognostic unfavorable (8.29e-4)" "unprognostic (2.80e-2)" "unprognostic (7.63e-2)" "potential prognostic favorable (8.65e-5)" "unprognostic (2.34e-1)" "unprognostic (1.50e-2)" "unprognostic (9.66e-2)" "unprognostic (5.53e-2)" "potential prognostic unfavorable (9.41e-6)" "unprognostic (3.48e-3)" "unprognostic (6.16e-2)" "unprognostic (1.28e-1)" "unprognostic (1.97e-1)" "unprognostic (8.52e-2)" "potential prognostic unfavorable (2.24e-4)" "unprognostic (1.28e-1)" "unprognostic (4.37e-2)" "unprognostic (1.44e-1)" "unprognostic (1.39e-2)" "unprognostic (5.27e-2)" "unprognostic (9.89e-2)" "unprognostic (1.48e-1)" "unprognostic (2.18e-1)" "unprognostic (4.57e-2)" GNPTAB "GNPTA, KIAA1208, MGC4170" ENSG00000111670 "N-acetylglucosamine-1-phosphate transferase subunits alpha and beta" Q3T906 12 101745499-101830959 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Transferase "Cancer-related genes, Disease variant, Mucolipidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 771.1;Lacrimal acinar cells: 444.8;Mast cells: 400.7;NK-cells: 335.5;Prostatic club cells: 521.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pituitary gland - Thyrotropes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014558, HPA042343" Approved Supported "Golgi apparatus" NA NA 63000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 51: Neurons - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 7 "Golgi apparatus" "HPA014558: , HPA042343: " "unprognostic (6.98e-3)" "unprognostic (1.12e-1)" "unprognostic (1.44e-1)" "unprognostic (2.21e-1)" "unprognostic (2.23e-2)" "unprognostic (9.92e-2)" "unprognostic (7.49e-2)" "unprognostic (2.44e-1)" "unprognostic (1.80e-1)" "unprognostic (6.97e-2)" "potential prognostic favorable (3.36e-5)" "unprognostic (1.97e-1)" "unprognostic (1.24e-1)" "unprognostic (1.67e-1)" "unprognostic (1.62e-1)" "unprognostic (6.29e-2)" "unprognostic (4.60e-1)" "unprognostic (7.81e-2)" "unprognostic (4.12e-2)" "unprognostic (1.48e-2)" "unprognostic (1.26e-3)" "unprognostic (5.05e-2)" "unprognostic (1.16e-1)" "unprognostic (1.39e-1)" "unprognostic (8.50e-2)" "unprognostic (4.48e-1)" "unprognostic (6.47e-2)" "unprognostic (3.68e-1)" "unprognostic (4.40e-1)" "unprognostic (1.21e-1)" "unprognostic (2.85e-1)" GNPTG "C16orf27, c316G12.3, CAB56184, GNPTAG" ENSG00000090581 "N-acetylglucosamine-1-phosphate transferase subunit gamma" Q9UJJ9 16 1351931-1365737 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Mucolipidosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 132.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pituitary gland - Gonadotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004055 Approved Approved "Endoplasmic reticulum,Cytosol" "Intracellular and membrane" "No annotated function" NA NA 92000000 "Cluster 29: Non-specific - Unknown function" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 27: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 11 "Endoplasmic reticulum" Cytosol "HPA004055: " "unprognostic (1.91e-1)" "unprognostic (6.32e-2)" "unprognostic (1.61e-2)" "unprognostic (2.06e-1)" "unprognostic (1.03e-1)" "unprognostic (3.25e-2)" "unprognostic (1.23e-2)" "unprognostic (3.42e-1)" "unprognostic (2.42e-1)" "unprognostic (3.69e-1)" "unprognostic (1.66e-1)" "unprognostic (3.01e-3)" "unprognostic (4.78e-2)" "potential prognostic unfavorable (4.47e-5)" "unprognostic (2.22e-1)" "unprognostic (1.94e-1)" "unprognostic (2.76e-1)" "unprognostic (4.72e-2)" "unprognostic (4.17e-1)" "unprognostic (4.99e-2)" "unprognostic (4.07e-2)" "unprognostic (3.68e-2)" "unprognostic (3.60e-1)" "unprognostic (2.44e-1)" "unprognostic (8.55e-2)" "unprognostic (3.47e-2)" "unprognostic (2.01e-1)" "unprognostic (1.67e-1)" "unprognostic (1.64e-1)" "unprognostic (6.40e-2)" "unprognostic (4.42e-2)" GNRH1 "GNRH, GRH, LHRH" ENSG00000147437 "Gonadotropin releasing hormone 1" P01148 8 25419258-25424654 "Disease related genes, Human disease related genes, Predicted secreted proteins" Hormone "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibro-adipogenic progenitors: 12.2;Innate lymphoid cells: 10.3;Leydig cells: 13.9;Other brain neurons: 11.4;Peritubular myoid cells: 15.1;Thymocytes: 11.0" "Cell type enhanced" "Detected in all" "fibroblast: 30.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells" "Group enriched" "Detected in many" 4 "basal ganglia: 19.7;hypothalamus: 12.1;olfactory bulb: 6.7" "Group enriched" "Detected in many" 13 "basal ganglia: 9.9;hypothalamus: 22.8" HPA027532 Supported "Secreted to blood" Hormone NA NA "Cluster 64: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 56: Non-specific - Sensory perception" "Cluster 109: Neurons - Neuronal signaling" "HPA027532: " "unprognostic (6.65e-2)" "unprognostic (1.00e-2)" "unprognostic (1.07e-2)" "unprognostic (3.13e-1)" "unprognostic (2.89e-1)" "unprognostic (2.91e-2)" "unprognostic (2.75e-2)" "potential prognostic unfavorable (1.67e-7)" "unprognostic (1.45e-1)" "unprognostic (3.91e-2)" "unprognostic (6.53e-2)" "unprognostic (6.33e-2)" "unprognostic (1.10e-1)" "unprognostic (6.73e-2)" "unprognostic (2.47e-1)" "unprognostic (2.59e-2)" "unprognostic (1.41e-1)" "unprognostic (1.21e-2)" "unprognostic (2.50e-1)" "unprognostic (4.83e-2)" "unprognostic (1.58e-2)" "unprognostic (1.19e-2)" "unprognostic (3.08e-2)" "unprognostic (2.34e-1)" "unprognostic (2.54e-2)" GNRH2 ENSG00000125787 "Gonadotropin releasing hormone 2" O43555 20 3043622-3045747 "Predicted secreted proteins" Hormone "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Epicardial cells: 2.3;Epididymal efferent duct absorptive cells: 1.5;Gastric chief cells: 10.9;Late spermatids: 3.4;Neuroendocrine cells: 3.7;Oocytes: 4.6;Pericytes: 1.7" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 7.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" HPA004338 Uncertain "Secreted to blood" Hormone NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 15: Non-specific - Transcription" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 110: Mural cells - ECM organization" "HPA004338: " "unprognostic (2.13e-1)" "unprognostic (9.05e-2)" "unprognostic (1.39e-1)" "unprognostic (5.58e-2)" "unprognostic (2.80e-2)" "unprognostic (6.02e-2)" "unprognostic (3.16e-2)" "unprognostic (2.10e-3)" GNRHR "GRHR, LHRHR" ENSG00000109163 "Gonadotropin releasing hormone receptor" P30968 4 67737118-67754388 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 16 "pituitary gland: 11.9" "Cell type enriched" "Detected in many" 4 "Gonadotrophs: 406.2" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pituitary gland - Gonadotropes" "Not detected" "Not detected" HPA013424 Enhanced NA NA "Cluster 20: Pituitary gland - Hormone signaling" "Cluster 24: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" "HPA013424: " GNS ENSG00000135677 "Glucosamine (N-acetyl)-6-sulfatase" P15586 12 64713445-64759431 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 312.4;Kupffer cells: 391.5;monocytes: 277.9;Neutrophils: 406.7;Retinal pigment epithelial cells: 247.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 229.4" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adrenal gland - Adrenal cortex cells, Spleen - Macrophages, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013695, CAB026011, HPA048508" Enhanced "Intracellular and membrane" Enzyme NA NA 1300000 "Cluster 40: Monocytes - Innate immune response" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 38: Non-specific - Transcription" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 7 "CAB026011: , HPA013695: , HPA048508: " "unprognostic (2.82e-1)" "unprognostic (2.02e-2)" "unprognostic (2.93e-1)" "unprognostic (1.00e-1)" "unprognostic (1.51e-1)" "unprognostic (1.51e-2)" "unprognostic (1.13e-2)" "unprognostic (2.92e-3)" "unprognostic (1.98e-1)" "unprognostic (2.68e-3)" "potential prognostic favorable (2.15e-6)" "unprognostic (4.99e-2)" "unprognostic (4.63e-2)" "potential prognostic unfavorable (3.42e-4)" "unprognostic (1.58e-2)" "unprognostic (2.54e-1)" "unprognostic (4.09e-1)" "unprognostic (2.94e-2)" "unprognostic (7.73e-2)" "unprognostic (1.93e-2)" "unprognostic (2.70e-3)" "unprognostic (2.00e-2)" "unprognostic (5.79e-3)" "unprognostic (1.35e-1)" "unprognostic (9.00e-2)" "unprognostic (6.21e-3)" "unprognostic (4.71e-2)" "unprognostic (5.55e-3)" "unprognostic (3.44e-2)" "unprognostic (8.62e-2)" "unprognostic (2.32e-1)" GOLGA1 "golgin-97, MGC33154" ENSG00000136935 "Golgin A1" Q92805 9 124878275-124948492 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 186.3;Rod photoreceptor cells: 153.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013065, HPA044329, HPA050555" Supported Enhanced "Golgi apparatus" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 47: Testis - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 79: Photoreceptor cells - Phototransduction" 13 "Golgi apparatus" "CAB013065: , HPA044329: , HPA050555: " "unprognostic (1.09e-1)" "unprognostic (7.04e-3)" "unprognostic (3.71e-2)" "unprognostic (3.13e-2)" "unprognostic (1.86e-1)" "unprognostic (2.52e-3)" "unprognostic (1.13e-1)" "unprognostic (1.46e-1)" "unprognostic (5.66e-2)" "unprognostic (1.37e-1)" "potential prognostic favorable (5.02e-6)" "unprognostic (7.41e-3)" "unprognostic (7.92e-2)" "unprognostic (4.30e-1)" "unprognostic (7.89e-2)" "unprognostic (3.81e-1)" "unprognostic (1.27e-1)" "unprognostic (2.12e-2)" "unprognostic (1.08e-1)" "unprognostic (2.95e-2)" "unprognostic (3.04e-1)" "unprognostic (8.65e-2)" "unprognostic (6.43e-2)" "unprognostic (2.01e-1)" "unprognostic (2.99e-3)" "unprognostic (7.36e-2)" "unprognostic (9.93e-2)" "unprognostic (6.78e-3)" "unprognostic (1.65e-1)" "unprognostic (7.41e-3)" "unprognostic (2.74e-1)" GOLGA2 "GM130, golgin-95" ENSG00000167110 "Golgin A2" Q08379 9 128255829-128276026 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Protein transport, Transport" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 299.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Pituitary gland - Somatotropes" "Low region specificity" "Detected in all" "CAB015421, HPA021178, HPA021230, HPA021799" Enhanced Enhanced "Golgi apparatus" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Secretory pathway" 440 "Golgi apparatus" "CAB015421: , HPA021178: , HPA021230: , HPA021799: " "unprognostic (4.68e-3)" "unprognostic (1.86e-2)" "unprognostic (2.35e-1)" "unprognostic (7.33e-3)" "unprognostic (2.38e-2)" "potential prognostic unfavorable (4.12e-4)" "unprognostic (8.99e-2)" "unprognostic (3.28e-1)" "unprognostic (3.73e-1)" "unprognostic (3.49e-1)" "potential prognostic favorable (4.33e-4)" "unprognostic (1.01e-2)" "unprognostic (1.65e-3)" "unprognostic (6.44e-2)" "unprognostic (4.82e-1)" "unprognostic (1.82e-1)" "unprognostic (3.68e-3)" "unprognostic (6.15e-2)" "unprognostic (1.02e-1)" "unprognostic (2.08e-1)" "unprognostic (3.49e-3)" "unprognostic (2.73e-1)" "unprognostic (9.67e-2)" "unprognostic (1.54e-2)" "unprognostic (7.64e-2)" "unprognostic (6.07e-2)" "unprognostic (1.14e-1)" "unprognostic (3.36e-1)" "unprognostic (1.59e-1)" "unprognostic (2.84e-1)" "unprognostic (1.10e-1)" GOLGA3 "GCP170, golgin-160, MEA-2" ENSG00000090615 "Golgin A3" Q08378 12 132768902-132829143 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039809, HPA040044" Enhanced Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 40: Non-specific - Mixed function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 9 "Golgi apparatus" Nucleoplasm "HPA039809: , HPA040044: " "unprognostic (7.90e-3)" "unprognostic (4.47e-2)" "unprognostic (1.50e-1)" "unprognostic (3.31e-2)" "unprognostic (2.80e-1)" "unprognostic (2.91e-3)" "unprognostic (1.63e-1)" "unprognostic (1.30e-1)" "unprognostic (8.30e-2)" "unprognostic (8.59e-3)" "unprognostic (5.79e-2)" "unprognostic (9.76e-2)" "unprognostic (1.20e-1)" "potential prognostic unfavorable (6.46e-5)" "unprognostic (2.15e-3)" "unprognostic (1.23e-1)" "unprognostic (3.12e-3)" "unprognostic (5.29e-3)" "unprognostic (4.75e-2)" "unprognostic (2.30e-2)" "unprognostic (1.51e-1)" "unprognostic (1.61e-2)" "unprognostic (2.07e-1)" "unprognostic (2.89e-1)" "unprognostic (1.27e-2)" "potential prognostic favorable (6.51e-4)" "unprognostic (1.23e-1)" "unprognostic (3.66e-2)" "unprognostic (3.24e-1)" "unprognostic (4.44e-3)" "unprognostic (1.56e-1)" GOLGA4 "GCP2, GOLG, golgin-240, p230" ENSG00000144674 "Golgin A4" Q13439 3 37243191-37366879 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "HPA035102, HPA040675" Supported Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Secretory pathway" 10 "Golgi apparatus" Nucleoplasm "HPA035102: , HPA040675: " "unprognostic (1.32e-1)" "unprognostic (5.17e-2)" "unprognostic (2.55e-1)" "unprognostic (3.73e-2)" "unprognostic (3.59e-2)" "unprognostic (2.87e-1)" "unprognostic (1.33e-1)" "unprognostic (4.71e-2)" "unprognostic (3.55e-1)" "unprognostic (3.43e-3)" "potential prognostic favorable (3.79e-4)" "unprognostic (1.91e-2)" "unprognostic (7.62e-2)" "potential prognostic unfavorable (2.01e-4)" "unprognostic (1.95e-1)" "unprognostic (1.05e-1)" "unprognostic (6.01e-2)" "unprognostic (6.69e-2)" "unprognostic (3.16e-2)" "unprognostic (9.22e-2)" "potential prognostic unfavorable (6.32e-4)" "unprognostic (5.30e-3)" "unprognostic (2.79e-2)" "unprognostic (1.58e-1)" "unprognostic (8.43e-2)" "unprognostic (7.67e-2)" "unprognostic (8.01e-2)" "unprognostic (1.03e-1)" "unprognostic (2.84e-1)" "unprognostic (1.39e-2)" "unprognostic (9.51e-2)" GOLGA5 "golgin-84, GOLIM5, ret-II, rfg5" ENSG00000066455 "Golgin A5" Q8TBA6 14 92794305-92839947 "Cancer-related genes, Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000992, HPA063876" Enhanced Supported Supported "Golgi apparatus" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 22: Epididymis - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 8: Non-specific - Secretory pathway" 18 "Golgi apparatus" "HPA000992: , HPA063876: " "unprognostic (1.95e-1)" "unprognostic (8.34e-2)" "unprognostic (3.83e-2)" "unprognostic (4.17e-2)" "unprognostic (4.05e-1)" "unprognostic (1.19e-2)" "unprognostic (3.59e-1)" "unprognostic (9.97e-3)" "unprognostic (1.97e-3)" "unprognostic (2.59e-3)" "unprognostic (3.72e-2)" "unprognostic (2.08e-2)" "unprognostic (4.69e-2)" "unprognostic (2.63e-2)" "unprognostic (1.10e-1)" "unprognostic (6.65e-2)" "unprognostic (4.95e-3)" "unprognostic (8.25e-2)" "unprognostic (1.19e-1)" "unprognostic (2.94e-1)" "potential prognostic unfavorable (3.35e-5)" "unprognostic (6.55e-2)" "unprognostic (2.69e-1)" "unprognostic (1.62e-1)" "unprognostic (1.09e-1)" "unprognostic (4.55e-3)" "unprognostic (2.87e-1)" "unprognostic (6.17e-2)" "unprognostic (1.20e-1)" "unprognostic (2.02e-1)" "unprognostic (1.95e-1)" GOLGA6A "GLP, GOLGA6" ENSG00000159289 "Golgin A6 family member A" Q9NYA3 15 74069857-74082550 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 12.2" "Group enriched" "Detected in some" 12 "Early spermatids: 27.9;Late primary spermatocytes: 20.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "HPA044978, HPA050087, HPA072134" Supported Approved Nucleoplasm,Vesicles,Centrosome NA NA "Cluster 47: Testis - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" 39 Vesicles "Nucleoplasm, Centrosome" "HPA044978: , HPA050087: , HPA072134: " GOLGA6B ENSG00000215186 "Golgin A6 family member B" A6NDN3 15 72654697-72669599 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 13 "liver: 4.0;testis: 6.1" "Group enriched" "Detected in some" 5 "Early spermatids: 9.8;Late primary spermatocytes: 7.0;Retinal pigment epithelial cells: 4.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes, Testis - Early spermatids" "HPA044978, HPA050087, HPA072134" Supported Approved Nucleoplasm,Vesicles,Centrosome NA NA "Cluster 47: Testis - Mixed function" "Cluster 20: Myeloma - Immune response" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" Vesicles "Nucleoplasm, Centrosome" "HPA044978: , HPA050087: , HPA072134: " GOLGA6C ENSG00000167195 "Golgin A6 family member C" A6NDK9 15 75258334-75273455 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 7 "liver: 3.5;testis: 11.5" "Group enriched" "Detected in some" 8 "Early spermatids: 34.8;Late primary spermatocytes: 24.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "HPA044978, HPA050087, HPA072134" Supported Approved Nucleoplasm,Vesicles,Centrosome NA NA "Cluster 47: Testis - Mixed function" "Cluster 25: Non-specific - Transcription" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" Vesicles "Nucleoplasm, Centrosome" "HPA044978: , HPA050087: , HPA072134: " "unprognostic (6.48e-3)" GOLGA6D ENSG00000140478 "Golgin A6 family member D" P0CG33 15 75282835-75295807 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 26 "testis: 6.2" "Cell type enhanced" "Detected in some" "Early spermatids: 11.4;Late primary spermatocytes: 9.6;Late spermatids: 2.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "HPA044978, HPA050087, HPA072134" Supported Approved Nucleoplasm,Vesicles,Centrosome NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" Vesicles "Nucleoplasm, Centrosome" "HPA044978: , HPA050087: , HPA072134: " GOLGA6L1 ENSG00000273976 "Golgin A6 family like 1" Q8N7Z2 15 23127066-23136822 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 72 "testis: 12.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047733 Uncertain NA NA "Cluster 79: Testis - Spermatogenesis" "HPA047733: " GOLGA6L10 GOLGA6L18 ENSG00000278662 "Golgin A6 family like 10" A6NI86 15 82339993-82349475 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "testis: 9.2" "Group enriched" "Detected in many" 5 "Early spermatids: 85.3;Late primary spermatocytes: 59.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" NA NA "Cluster 21: Testis - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" "unprognostic (1.31e-2)" GOLGA6L2 "CT105, FLJ36144" ENSG00000174450 "Golgin A6 family like 2" Q8N9W4 15 23439038-23447243 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 42 "testis: 46.8" "Group enriched" "Detected in some" 9 "Early spermatids: 91.9;Late primary spermatocytes: 107.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Myeloma: 1.2" "Testis - Early spermatids, Testis - Late spermatids" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 20: Myeloma - Immune response" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" 1 GOLGA6L22 ENSG00000277865 "Golgin A6 family like 22" H0YM25 15 22458903-22469226 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 65 "testis: 9.4" "Group enriched" "Detected in some" 6 "Early spermatids: 18.1;Late primary spermatocytes: 10.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047733 Uncertain NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" "HPA047733: " GOLGA6L24 GOLGA6L24P ENSG00000237850 "Golgin A6 family like 24" 15 28347851-28358084 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Group enriched" "Detected in some" 53 "Early spermatids: 11.9;Late primary spermatocytes: 4.4;Late spermatids: 3.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047733 Uncertain NA NA "Cluster 51: Myeloma - Immunoglobulins" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" "HPA047733: " GOLGA6L25 GOLGA6L25P ENSG00000227717 "Golgin A6 family like 25" 15 28553568-28563779 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047733 Uncertain NA NA "HPA047733: " GOLGA6L26 ENSG00000273756 "Golgin A6 family like 26" 15 23324535-23334196 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047733 Uncertain NA NA "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" "HPA047733: " GOLGA6L4 ENSG00000184206 "Golgin A6 family like 4" A6NEF3 15 84235773-84245358 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 6.6;Early spermatids: 7.5;Late primary spermatocytes: 2.5;Loop of henle epithelial cells: 3.9;Papillary tip epithelial cells: 3.1;Podocytes: 3.6;Proximal tubule cells: 7.5;Renal collecting duct intercalated cells: 10.3;Renal collecting duct principal cells: 3.4;Renal connecting tubule cells: 4.6" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 1.1;NK-cell: 2.3" "Group enriched" "Detected in many" 6 "granulocytes: 1.1;NK-cells: 2.3" "Low cancer specificity" "Detected in many" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" "unprognostic (4.73e-2)" "unprognostic (9.36e-2)" "unprognostic (2.01e-2)" "unprognostic (1.14e-1)" "potential prognostic unfavorable (2.37e-7)" "unprognostic (4.26e-2)" "unprognostic (8.85e-2)" "unprognostic (3.65e-2)" "unprognostic (2.00e-2)" "unprognostic (2.66e-1)" "unprognostic (9.25e-2)" "unprognostic (1.37e-2)" "unprognostic (6.40e-2)" "potential prognostic favorable (5.60e-4)" "unprognostic (7.19e-3)" "unprognostic (2.09e-1)" "unprognostic (1.32e-1)" "unprognostic (1.32e-1)" "unprognostic (1.35e-1)" "unprognostic (3.73e-3)" GOLGA6L6 FLJ36131 ENSG00000277322 "Golgin A6 family like 6" A8MZA4 15 20531856-20541800 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 49 "testis: 4.8" "Cell type enhanced" "Detected in some" "Early spermatids: 1.9;Late primary spermatocytes: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047733 Uncertain NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" "HPA047733: " GOLGA6L7 GOLGA6L7P ENSG00000261649 "Golgin A6 family like 7" A0A1B0GV03 15 28841832-28848675 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 65 "testis: 26.2" "Group enriched" "Detected in some" 13 "Early spermatids: 174.9;Late primary spermatocytes: 159.6" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Kidney Chromophobe (TCGA): 1.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney cancer: 1.7" "Testis - Early spermatids, Testis - Late spermatids" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 9: Non-specific - Receptor signaling" "Cluster 20: Myeloma - Immune response" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" "unprognostic (9.68e-3)" "unprognostic (6.34e-3)" "unprognostic (1.86e-1)" GOLGA6L9 GOLGA6L20 ENSG00000197978 "Golgin A6 family like 9" A6NEM1 15 82429816-82439153 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 4.9;Early spermatids: 6.5;Esophageal apical cells: 6.9;Esophageal suprabasal cells: 3.8;Fallopian tube ciliated cells: 3.2;Late primary spermatocytes: 4.6;Loop of henle epithelial cells: 6.0;Papillary tip epithelial cells: 6.0;Podocytes: 5.9;Proximal tubule cells: 6.0;Renal collecting duct intercalated cells: 8.2;Renal connecting tubule cells: 5.1;Retinal ganglion cells: 3.9" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in some" 4 "choroid plexus: 4.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Stomach - Gastric mucous cells, Testis - Early spermatids" NA NA "Cluster 32: Basophils - Transcription" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 105: Non-specific - Mixed function" 177 "unprognostic (1.70e-2)" GOLGA7 "GCP16, GOLGA3AP1, GOLGA7A, HSPC041" ENSG00000147533 "Golgin A7" Q7Z5G4 8 41488200-41511095 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 188.3;Neutrophils: 295.8;Oocytes: 303.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046878 Uncertain NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 40: Non-specific - Unknown function" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 39 "HPA046878: " "unprognostic (2.63e-2)" "unprognostic (5.84e-2)" "unprognostic (2.17e-1)" "unprognostic (6.95e-2)" "unprognostic (2.74e-2)" "unprognostic (2.51e-1)" "unprognostic (1.70e-1)" "unprognostic (3.19e-2)" "unprognostic (5.99e-2)" "unprognostic (4.78e-3)" "potential prognostic favorable (1.42e-8)" "unprognostic (1.13e-2)" "unprognostic (2.83e-3)" "unprognostic (2.10e-2)" "unprognostic (1.66e-2)" "unprognostic (1.55e-1)" "unprognostic (2.50e-1)" "unprognostic (2.29e-2)" "unprognostic (1.41e-2)" "unprognostic (1.80e-1)" "unprognostic (2.15e-3)" "unprognostic (1.90e-1)" "unprognostic (1.84e-1)" "unprognostic (1.27e-1)" "unprognostic (3.78e-2)" "unprognostic (9.03e-2)" "unprognostic (8.35e-2)" "unprognostic (1.67e-1)" "unprognostic (1.42e-1)" "unprognostic (4.89e-2)" "unprognostic (3.28e-1)" GOLGA7B "bA451M19.3, bA459F3.4, C10orf132, C10orf133" ENSG00000155265 "Golgin A7 family member B" Q2TAP0 10 97849843-97871580 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 55.3;epididymis: 22.1" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 21.3;Astrocytes: 29.9;Bergmann glia: 80.6;Brain excitatory neurons: 38.4;Brain inhibitory neurons: 22.7;Cholangiocytes: 19.0;Choroid plexus epithelial cells: 21.5;Epididymal basal cells: 20.3;Epididymal principal cells: 33.8;Gonadotrophs: 21.3;Late spermatids: 25.5;Melanocytes: 22.2;Other brain neurons: 27.4;Pancreatic duct cells: 18.9;Pancreatic islet cells: 28.6;Thymic myoid cells: 25.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 10.4" "Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Liver - Cholangiocytes, Spleen - T-cells, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046878 Uncertain NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 98: Neurons - Neurotransmission & signaling" 4 "HPA046878: " "unprognostic (7.94e-2)" "unprognostic (1.95e-2)" "unprognostic (2.56e-2)" "validated prognostic unfavorable (8.36e-4)" "validated prognostic unfavorable (4.00e-4)" "unprognostic (2.73e-2)" "unprognostic (9.42e-2)" "unprognostic (1.45e-1)" "unprognostic (1.41e-3)" "unprognostic (1.43e-1)" "unprognostic (1.08e-1)" "unprognostic (8.39e-2)" "unprognostic (5.01e-2)" "unprognostic (7.19e-2)" "unprognostic (1.21e-1)" "unprognostic (1.22e-1)" "unprognostic (5.35e-2)" "unprognostic (5.44e-2)" "unprognostic (8.36e-2)" "unprognostic (2.34e-1)" "unprognostic (2.05e-1)" "unprognostic (2.53e-1)" "unprognostic (2.44e-3)" "unprognostic (6.48e-2)" GOLGA8A "CFAP286, FAP286, GM88, GOLGIN-67" ENSG00000175265 "Golgin A8 family member A" A7E2F4 15 34378935-34437808 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oligodendrocyte progenitor cells: 189.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" HPA051808 Approved Approved "Golgi apparatus,Cytosol" NA Yes "Cluster 22: Epididymis - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 56: Non-specific - Sensory perception" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" "Golgi apparatus" Cytosol "HPA051808: " "unprognostic (1.31e-1)" "unprognostic (1.83e-1)" "unprognostic (3.54e-1)" "unprognostic (3.03e-3)" "unprognostic (6.18e-2)" "unprognostic (5.17e-2)" "unprognostic (9.34e-3)" "unprognostic (1.52e-3)" "unprognostic (6.17e-2)" "unprognostic (1.08e-2)" "potential prognostic unfavorable (1.79e-5)" "unprognostic (1.33e-2)" "unprognostic (7.06e-2)" "unprognostic (1.16e-2)" "unprognostic (3.30e-2)" "unprognostic (3.52e-2)" "unprognostic (2.81e-1)" "unprognostic (3.56e-3)" "unprognostic (3.22e-1)" "unprognostic (1.43e-1)" "unprognostic (2.10e-1)" "unprognostic (1.35e-2)" "potential prognostic unfavorable (8.15e-4)" "unprognostic (1.13e-1)" "unprognostic (9.88e-2)" "unprognostic (2.29e-2)" "unprognostic (7.54e-2)" "unprognostic (2.58e-1)" "unprognostic (1.04e-1)" "unprognostic (1.65e-1)" "unprognostic (1.69e-2)" GOLGA8B ENSG00000215252 "Golgin A8 family member B" A8MQT2 15 34525095-34588503 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "pancreas: 193.0" "Cell type enhanced" "Detected in many" "Gonadotrophs: 171.1;Podocytes: 166.0;Sertoli cells: 188.6;Somatotrophs: 200.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Thyroid Carcinoma (TCGA): 41.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" HPA051808 Approved Approved "Golgi apparatus,Cytosol" NA Yes "Cluster 70: Non-specific - Protein processing" "Cluster 35: Non-specific - DNA binding" "Cluster 56: Non-specific - Sensory perception" "Cluster 9: T-cells - Adaptive immunity: Regulation" "Golgi apparatus" Cytosol "HPA051808: " "unprognostic (7.10e-2)" "unprognostic (3.01e-2)" "unprognostic (1.44e-1)" "unprognostic (5.31e-2)" "unprognostic (1.92e-1)" "unprognostic (2.47e-1)" "unprognostic (9.94e-3)" "unprognostic (4.81e-2)" "unprognostic (8.71e-2)" "potential prognostic unfavorable (6.66e-9)" "unprognostic (9.23e-2)" "unprognostic (1.44e-1)" "unprognostic (1.71e-2)" "unprognostic (3.15e-2)" "unprognostic (4.58e-2)" "unprognostic (2.44e-1)" "unprognostic (2.62e-1)" "unprognostic (1.35e-1)" "unprognostic (1.45e-1)" "unprognostic (1.74e-2)" "unprognostic (2.75e-3)" "potential prognostic unfavorable (6.32e-4)" "unprognostic (1.22e-2)" "unprognostic (1.74e-2)" "unprognostic (2.89e-1)" "unprognostic (3.16e-1)" "unprognostic (5.93e-2)" "unprognostic (2.67e-1)" "unprognostic (6.00e-3)" GOLGA8F DKFZp434P162 ENSG00000153684 "Golgin A8 family member F" Q08AF8 15 28378621-28392021 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" NA NA "Cluster 51: Myeloma - Immunoglobulins" 21 GOLGA8G DKFZp434K052 ENSG00000183629 "Golgin A8 family member G" 15 28519611-28533014 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 4 "testis: 3.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" GOLGA8H GOLGA6L11 ENSG00000261794 "Golgin A8 family member H" P0CJ92 15 30604028-30617752 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "testis: 4.7" "Cell type enhanced" "Detected in some" "Early primary spermatocytes: 3.7;Early spermatids: 9.6;Endometrial ciliated cells: 3.0;Fallopian tube ciliated cells: 3.1;Late primary spermatocytes: 12.2;Medullary thymic epithelial cells: 2.4;Renal collecting duct principal cells: 1.8" "Low cell type specificity" "Detected in single" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Testis - Early spermatids" NA NA "Cluster 21: Testis - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" "unprognostic (2.13e-1)" GOLGA8J ENSG00000179938 "Golgin A8 family member J" A6NMD2 15 30082955-30096690 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "testis: 3.8" "Group enriched" "Detected in some" 5 "Early spermatids: 5.8;Late primary spermatocytes: 5.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" GOLGA8K ENSG00000249931 "Golgin A8 family member K" D6RF30 15 32389599-32403292 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "testis: 4.9" "Group enriched" "Detected in some" 4 "Early spermatids: 9.8;Late primary spermatocytes: 10.2" "Cell type enhanced" "Detected in some" "mammillary body: 1.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Adrenocortical cancer: 1.6;Leukemia: 1.2" NA NA "Cluster 47: Testis - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" GOLGA8M ENSG00000188626 "Golgin A8 family member M" H3BSY2 15 28698583-28738384 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "thyroid gland: 21.1" "Cell type enhanced" "Detected in some" "Astrocytes: 6.6;Bergmann glia: 8.6;Distal convoluted tubule cells: 6.3;Ependymal cells: 5.6;Late primary spermatocytes: 4.6;Loop of henle epithelial cells: 7.1;Microglia: 3.8;NK-cells: 3.3;Podocytes: 4.6;Proximal tubule cells: 9.5;Renal collecting duct intercalated cells: 6.1;Renal collecting duct principal cells: 4.5;Renal connecting tubule cells: 4.8" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in single" "Thyroid Carcinoma (TCGA): 2.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 16 "Leukemia: 8.9" "Skin - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" NA NA "Cluster 21: Testis - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 105: Non-specific - Mixed function" "unprognostic (4.03e-3)" "unprognostic (6.66e-3)" "unprognostic (4.93e-2)" GOLGA8N ENSG00000232653 "Golgin A8 family member N" F8WBI6 15 32593456-32607310 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 7.8;Bergmann glia: 4.8;Choroid plexus epithelial cells: 6.5;Distal convoluted tubule cells: 11.5;Loop of henle epithelial cells: 11.3;Microglia: 7.1;Oligodendrocytes: 5.8;Papillary tip epithelial cells: 5.5;Podocytes: 12.6;Proximal tubule cells: 7.6;Renal collecting duct intercalated cells: 13.0;Renal collecting duct principal cells: 5.8;Renal connecting tubule cells: 12.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 9 "Leukemia: 16.1" NA NA "Cluster 70: Non-specific - Protein processing" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 102: Non-specific - Mixed function" "unprognostic (1.28e-1)" "unprognostic (2.07e-1)" "unprognostic (8.22e-2)" "unprognostic (3.12e-2)" "unprognostic (2.59e-1)" "unprognostic (7.76e-2)" "unprognostic (1.13e-2)" "unprognostic (1.33e-2)" "unprognostic (1.49e-2)" "unprognostic (4.51e-2)" "unprognostic (8.40e-2)" "unprognostic (2.55e-1)" GOLGA8O ENSG00000206127 "Golgin A8 family member O" A6NCC3 15 32441914-32455634 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 14.8" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.5;Early spermatids: 3.0;Hematopoietic stem cells: 5.8;Late primary spermatocytes: 2.5;Megakaryocyte progenitors: 2.2;Megakaryocyte-Erythroid progenitors: 2.6;NK-cells: 4.1;Thymocytes: 2.5" "Cancer enriched" "Detected in many" 4 "Thyroid Carcinoma (TCGA): 14.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "gdT-cell: 1.0;NK-cell: 2.3" "Group enriched" "Detected in many" 11 "NK-cells: 2.3;T-cells: 1.0" "Cancer enriched" "Detected in some" 9 "Leukemia: 14.2" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 22: Epididymis - Mixed function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" "unprognostic (1.70e-1)" "unprognostic (9.55e-2)" "unprognostic (1.15e-2)" "potential prognostic unfavorable (7.53e-4)" "unprognostic (7.25e-2)" "potential prognostic unfavorable (5.36e-5)" "unprognostic (1.55e-1)" "unprognostic (1.98e-1)" "unprognostic (6.08e-3)" "unprognostic (1.68e-1)" "unprognostic (9.32e-2)" "unprognostic (3.27e-2)" "unprognostic (6.03e-2)" "unprognostic (3.95e-3)" "unprognostic (1.53e-3)" "unprognostic (1.78e-1)" "unprognostic (4.55e-2)" "unprognostic (2.46e-1)" "unprognostic (2.89e-2)" "unprognostic (1.30e-2)" GOLGA8Q ENSG00000178115 "Golgin A8 family member Q" H3BV12 15 30552050-30565684 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "epididymis: 15.7;thyroid gland: 16.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Leukemia: 7.6" NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" "unprognostic (1.58e-2)" GOLGA8R ENSG00000186399 "Golgin A8 family member R" I6L899 15 30400562-30414260 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Gastric chief cells: 1.1;Kupffer cells: 1.0;Late spermatids: 1.1;pDCs: 1.8" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Thyroid Carcinoma (TCGA): 1.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 8 "Leukemia: 8.8" NA NA "Cluster 64: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" "unprognostic (3.50e-3)" "unprognostic (8.44e-2)" "unprognostic (5.47e-2)" "unprognostic (1.30e-3)" "unprognostic (1.09e-1)" GOLGA8S ENSG00000261739 "Golgin A8 family member S" H3BPF8 15 23354748-23368341 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 5 "testis: 3.2" "Cell type enhanced" "Detected in some" "Early spermatids: 1.7;Late primary spermatocytes: 3.9" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 28 "Myeloma: 21.0" "Testis - Early spermatids" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 53: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" GOLGA8T ENSG00000261247 "Golgin A8 family member T" H3BQL2 15 30135051-30148748 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "testis: 5.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" NA NA "Cluster 21: Testis - Mixed function" "Cluster 43: Hindbrain - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" GOLGB1 "GCP, GCP372, giantin, GOLIM1" ENSG00000173230 "Golgin B1" Q14789 3 121663199-121749966 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011008, HPA011555" Enhanced Enhanced "Golgi apparatus" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 31 "Golgi apparatus" "HPA011008: , HPA011555: " "unprognostic (6.63e-2)" "unprognostic (2.48e-3)" "unprognostic (4.32e-2)" "unprognostic (6.41e-2)" "unprognostic (8.78e-2)" "unprognostic (3.00e-1)" "unprognostic (2.66e-2)" "unprognostic (1.66e-1)" "unprognostic (1.39e-2)" "unprognostic (1.34e-1)" "potential prognostic favorable (2.16e-5)" "unprognostic (1.87e-1)" "unprognostic (1.40e-1)" "unprognostic (7.32e-2)" "unprognostic (2.77e-2)" "unprognostic (5.44e-2)" "unprognostic (2.05e-1)" "unprognostic (2.37e-1)" "unprognostic (1.34e-1)" "unprognostic (7.78e-2)" "unprognostic (1.13e-1)" "unprognostic (3.88e-3)" "unprognostic (8.91e-2)" "unprognostic (1.30e-1)" "unprognostic (4.59e-3)" "unprognostic (2.67e-1)" "unprognostic (3.40e-1)" "unprognostic (6.20e-2)" "unprognostic (1.68e-1)" "potential prognostic unfavorable (5.08e-4)" "unprognostic (2.73e-1)" GOLIM4 "GIMPC, GOLPH4, GPP130, P138" ENSG00000173905 "Golgi integral membrane protein 4" O00461 3 168008689-168095924 "Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Müller glia: 408.0;Podocytes: 323.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 10.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001677, HPA002315" Enhanced Enhanced "Golgi apparatus" NA NA 2200000 "Cluster 29: Non-specific - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 39: Astrocytes - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 11 "Golgi apparatus" "HPA001677: , HPA002315: " "unprognostic (1.98e-1)" "unprognostic (1.56e-1)" "unprognostic (1.93e-1)" "unprognostic (3.45e-2)" "unprognostic (4.26e-2)" "unprognostic (6.91e-3)" "unprognostic (1.27e-1)" "unprognostic (7.01e-2)" "unprognostic (3.98e-2)" "potential prognostic unfavorable (8.63e-4)" "validated prognostic favorable (1.52e-6)" "validated prognostic favorable (1.43e-4)" "unprognostic (1.84e-1)" "unprognostic (1.58e-2)" "unprognostic (1.42e-1)" "unprognostic (3.63e-2)" "unprognostic (8.51e-3)" "unprognostic (4.39e-2)" "unprognostic (1.16e-2)" "unprognostic (1.00e-1)" "potential prognostic unfavorable (6.51e-4)" "unprognostic (4.53e-2)" "unprognostic (4.01e-2)" "unprognostic (5.41e-3)" "unprognostic (2.41e-2)" "unprognostic (5.69e-2)" "unprognostic (1.36e-1)" "unprognostic (1.24e-1)" "unprognostic (2.42e-1)" "unprognostic (4.59e-2)" "unprognostic (1.51e-2)" GOLM1 "bA379P1.3, C9orf155, FLJ23608, GOLPH2, GP73" ENSG00000135052 "Golgi membrane protein 1" Q8NBJ4 9 86026146-86100173 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "stomach 1: 374.5" "Cell type enhanced" "Detected in many" "Colonocytes: 396.6;Conjunctival goblet cells: 342.7;Early spermatids: 437.2;Foveolar cells: 749.5;Late spermatids: 513.4;Respiratory deuterosomal cells: 343.1;Respiratory ionocytes: 607.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 683.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 2.2;classical monocyte: 3.5;gdT-cell: 3.5;intermediate monocyte: 2.6;neutrophil: 4.3;non-classical monocyte: 4.2;plasmacytoid DC: 1.4" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Spleen - Endothelial cells, Stomach - Gastric mucous cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010638, HPA011929, CAB015341" Enhanced Enhanced "Golgi apparatus" NA NA 44000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 77: Intestine - Digestion" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 7: Liver cancer - Metabolism" "Cluster 68: Foveolar cells - Mucosal defense" 52 "Golgi apparatus" "CAB015341: , HPA010638: , HPA011929: " "unprognostic (4.31e-1)" "unprognostic (7.37e-2)" "unprognostic (4.76e-2)" "unprognostic (3.69e-2)" "unprognostic (3.14e-3)" "unprognostic (1.19e-1)" "unprognostic (1.24e-1)" "unprognostic (9.61e-3)" "unprognostic (2.00e-3)" "unprognostic (1.04e-1)" "unprognostic (2.16e-1)" "unprognostic (3.04e-1)" "unprognostic (4.12e-1)" "potential prognostic unfavorable (9.53e-4)" "unprognostic (2.07e-2)" "potential prognostic unfavorable (2.26e-4)" "unprognostic (8.65e-2)" "unprognostic (1.17e-1)" "unprognostic (7.90e-2)" "unprognostic (3.64e-2)" "unprognostic (2.09e-1)" "unprognostic (1.79e-1)" "unprognostic (7.08e-2)" "unprognostic (1.46e-2)" "unprognostic (3.42e-1)" "unprognostic (4.88e-2)" "unprognostic (6.75e-2)" "unprognostic (1.15e-1)" "unprognostic (1.68e-1)" "unprognostic (1.02e-3)" "unprognostic (1.01e-2)" GOLM2 "CASC4, DKFZp459F1927, H63" ENSG00000166734 "Golgi membrane protein 2" Q6P4E1 15 44288719-44415758 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043015, HPA049488" Enhanced Enhanced "Golgi apparatus" NA NA 1500000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 65: Brain - Transcription" "Cluster 39: Astrocytes - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 4 "Golgi apparatus" "HPA043015: , HPA049488: " "unprognostic (2.25e-3)" "unprognostic (8.41e-3)" "unprognostic (1.49e-1)" "unprognostic (3.30e-1)" "unprognostic (2.31e-1)" "unprognostic (2.56e-1)" "unprognostic (1.25e-2)" "unprognostic (2.67e-1)" "unprognostic (1.09e-2)" "validated prognostic favorable (7.26e-9)" "validated prognostic favorable (9.05e-4)" "unprognostic (1.94e-1)" "unprognostic (1.08e-1)" "unprognostic (1.10e-1)" "unprognostic (5.87e-2)" "unprognostic (9.40e-2)" "unprognostic (1.49e-1)" "unprognostic (1.14e-2)" "unprognostic (1.36e-3)" "unprognostic (1.19e-1)" "unprognostic (1.31e-1)" "unprognostic (6.30e-2)" "unprognostic (4.07e-2)" "unprognostic (1.05e-2)" "unprognostic (1.01e-1)" "unprognostic (2.58e-1)" "unprognostic (1.40e-1)" "unprognostic (1.09e-1)" "unprognostic (1.34e-1)" GOLPH3 "GOPP1, GPP34, MIDAS, Vps74" ENSG00000113384 "Golgi phosphoprotein 3" Q9H4A6 5 32124716-32174319 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044564, HPA055841" Approved Supported "Golgi apparatus,Vesicles" NA NA 9400 "Cluster 45: Eosinophils - Unknown function" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 21: Non-specific - Metabolism" "Cluster 29: Non-specific - Unknown function" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 42 "Golgi apparatus, Vesicles" "HPA044564: , HPA055841: " "unprognostic (2.34e-2)" "unprognostic (3.39e-2)" "unprognostic (1.85e-2)" "unprognostic (9.18e-2)" "unprognostic (4.45e-2)" "unprognostic (1.26e-2)" "unprognostic (2.18e-1)" "potential prognostic unfavorable (2.07e-4)" "unprognostic (5.90e-2)" "unprognostic (1.47e-2)" "potential prognostic favorable (1.81e-5)" "unprognostic (8.42e-2)" "unprognostic (2.11e-2)" "unprognostic (4.18e-2)" "unprognostic (3.41e-2)" "unprognostic (9.21e-2)" "unprognostic (8.37e-3)" "unprognostic (1.75e-1)" "unprognostic (2.51e-1)" "unprognostic (1.48e-1)" "unprognostic (1.72e-1)" "unprognostic (5.68e-2)" "unprognostic (1.26e-2)" "unprognostic (2.28e-1)" "unprognostic (1.25e-1)" "unprognostic (4.79e-2)" "unprognostic (1.07e-1)" "unprognostic (1.31e-1)" "unprognostic (4.43e-1)" "unprognostic (1.62e-2)" "unprognostic (2.71e-1)" GOLPH3L GPP34R ENSG00000143457 "Golgi phosphoprotein 3 like" Q9H4A5 1 150646230-150697154 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 365.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072016 Supported "Golgi apparatus,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 45: Non-specific - Nuclear processes" "Cluster 84: Apical squamous epithelium - Cornification" 31 "Golgi apparatus" Cytosol "HPA072016: " "unprognostic (2.53e-2)" "unprognostic (4.65e-2)" "unprognostic (1.39e-1)" "unprognostic (6.68e-2)" "unprognostic (1.79e-2)" "unprognostic (7.32e-3)" "unprognostic (2.70e-1)" "unprognostic (6.55e-3)" "unprognostic (2.75e-1)" "unprognostic (8.14e-2)" "potential prognostic favorable (1.75e-6)" "unprognostic (4.61e-3)" "unprognostic (1.70e-2)" "unprognostic (1.24e-2)" "unprognostic (2.43e-1)" "unprognostic (3.82e-1)" "unprognostic (3.86e-1)" "unprognostic (3.43e-1)" "unprognostic (1.42e-1)" "unprognostic (7.59e-2)" "unprognostic (4.91e-2)" "unprognostic (1.43e-2)" "unprognostic (5.94e-3)" "unprognostic (3.01e-1)" "unprognostic (2.05e-2)" "unprognostic (4.17e-3)" "unprognostic (1.89e-2)" "unprognostic (3.98e-1)" "unprognostic (1.54e-1)" "unprognostic (1.57e-1)" "unprognostic (4.37e-2)" GOLT1A "CGI-141, FLJ42654, GOT1, MGC62027, YMR292W" ENSG00000174567 "Golgi transport 1A" Q6ZVE7 1 204198163-204213988 "Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 217.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 36.8;Cholangiocytes: 47.2;Enterocytes: 202.0;Hepatocytes: 163.1;Pancreatic islet cells: 53.9;Syncytiotrophoblasts: 41.2;Urothelial cells: 64.8" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 21.4" "Cancer enriched" "Detected in many" 5 "Liver Hepatocellular Carcinoma (TCGA): 162.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 36.4" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Breast - Breast glandular cells, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate basal glandular cells, Skin - Eccrine sweat gland cells" "Region enhanced" "Detected in many" "cerebral cortex: 9.0" "Low region specificity" "Detected in all" NA NA "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 1: Enterocytes - Absorption and Digestion" 26 "unprognostic (6.88e-2)" "unprognostic (1.26e-1)" "unprognostic (8.23e-2)" "unprognostic (2.36e-1)" "unprognostic (5.75e-2)" "unprognostic (2.42e-1)" "potential prognostic unfavorable (1.56e-4)" "unprognostic (2.08e-2)" "unprognostic (1.74e-2)" "unprognostic (3.07e-3)" "unprognostic (1.81e-1)" "potential prognostic unfavorable (5.55e-4)" "unprognostic (2.02e-1)" "unprognostic (6.55e-2)" "unprognostic (2.81e-1)" "unprognostic (1.75e-1)" "unprognostic (1.01e-3)" "unprognostic (3.65e-3)" "unprognostic (1.27e-2)" "unprognostic (4.41e-2)" "unprognostic (8.14e-2)" "unprognostic (4.19e-2)" "unprognostic (2.67e-1)" "potential prognostic unfavorable (1.79e-4)" "unprognostic (2.10e-1)" "unprognostic (7.74e-2)" "unprognostic (1.62e-1)" "unprognostic (7.05e-3)" "unprognostic (4.69e-2)" GOLT1B "CGI-141, GOT1, YMR292W" ENSG00000111711 "Golgi transport 1B" Q9Y3E0 12 21501781-21518408 "Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 133.1;Extravillous trophoblasts: 122.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055909, HPA066383" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 76: Non-specific - Metabolism" "Cluster 55: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 8: Non-specific - Secretory pathway" 34 Vesicles Nucleoplasm "HPA055909: , HPA066383: " "unprognostic (9.21e-2)" "unprognostic (1.84e-3)" "potential prognostic unfavorable (2.91e-4)" "unprognostic (1.05e-2)" "unprognostic (3.39e-1)" "unprognostic (1.07e-1)" "unprognostic (2.06e-1)" "unprognostic (4.78e-2)" "unprognostic (1.58e-2)" "unprognostic (2.38e-2)" "potential prognostic unfavorable (2.33e-4)" "unprognostic (1.02e-3)" "unprognostic (5.33e-3)" "validated prognostic unfavorable (6.74e-5)" "validated prognostic unfavorable (2.33e-4)" "unprognostic (1.39e-3)" "potential prognostic unfavorable (1.77e-4)" "unprognostic (3.49e-1)" "unprognostic (7.13e-2)" "unprognostic (8.51e-3)" "unprognostic (3.24e-2)" "unprognostic (7.54e-3)" "potential prognostic unfavorable (8.34e-7)" "unprognostic (3.69e-1)" "unprognostic (4.70e-2)" "unprognostic (3.76e-1)" "unprognostic (1.34e-2)" "unprognostic (7.58e-2)" "unprognostic (2.21e-1)" "unprognostic (1.33e-1)" "unprognostic (5.16e-2)" GON4L "FLJ20203, GON-4, GON4, YARP" ENSG00000116580 "Gon-4 like" Q3T8J9 1 155749659-155859400 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006986, HPA057305, HPA074504" Uncertain Enhanced "Nucleoplasm,Nuclear bodies" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 49: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 45: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" 6 "Nucleoplasm, Nuclear bodies" "HPA006986: , HPA057305: , HPA074504: " "unprognostic (2.56e-1)" "unprognostic (1.64e-1)" "unprognostic (4.49e-2)" "unprognostic (2.55e-2)" "unprognostic (1.89e-1)" "unprognostic (2.58e-1)" "unprognostic (1.66e-2)" "unprognostic (2.87e-2)" "unprognostic (1.48e-1)" "unprognostic (3.61e-3)" "validated prognostic favorable (2.55e-4)" "validated prognostic favorable (3.87e-4)" "unprognostic (3.46e-1)" "unprognostic (1.52e-2)" "unprognostic (2.00e-1)" "unprognostic (2.67e-1)" "unprognostic (1.32e-3)" "unprognostic (1.40e-1)" "unprognostic (5.46e-2)" "unprognostic (9.95e-2)" "unprognostic (4.51e-2)" "unprognostic (1.90e-1)" "unprognostic (1.16e-2)" "unprognostic (1.63e-1)" "unprognostic (8.82e-2)" "unprognostic (9.93e-3)" "unprognostic (1.49e-1)" "unprognostic (3.68e-1)" "unprognostic (7.41e-2)" "unprognostic (4.59e-3)" "unprognostic (1.14e-1)" GON7 C14orf142 ENSG00000170270 "GON7 subunit of KEOPS complex" Q9BXV9 14 93202894-93207065 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 9.1;Early spermatids: 88.2;Ependymal cells: 19.3;Late primary spermatocytes: 40.0;Late spermatids: 8.8;Other brain neurons: 9.4;Tuft cells: 11.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 6.3" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051832 Approved Supported "Nucleoplasm,Nucleoli rim" NA NA 9900 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 17: Choroid plexus - Cilium" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 13 "Nucleoplasm, Nucleoli rim" "HPA051832: " "unprognostic (3.02e-2)" "unprognostic (3.28e-1)" "unprognostic (4.45e-3)" "unprognostic (3.69e-3)" "unprognostic (1.47e-2)" "unprognostic (7.14e-2)" "unprognostic (1.41e-3)" "unprognostic (3.87e-2)" "unprognostic (1.14e-1)" "potential prognostic favorable (3.72e-6)" "unprognostic (1.38e-3)" "unprognostic (1.66e-1)" "potential prognostic unfavorable (3.36e-5)" "unprognostic (8.15e-2)" "unprognostic (2.15e-1)" "unprognostic (1.05e-1)" "unprognostic (2.26e-1)" "potential prognostic favorable (1.57e-4)" "unprognostic (2.21e-1)" "unprognostic (1.08e-1)" "unprognostic (2.89e-1)" "unprognostic (1.10e-2)" "unprognostic (1.34e-1)" "unprognostic (3.07e-2)" "unprognostic (5.70e-2)" "unprognostic (4.64e-1)" "unprognostic (6.80e-2)" "unprognostic (3.39e-2)" "unprognostic (3.66e-1)" GOPC "CAL, dJ94G16.2, FIG, GOPC1, PIST" ENSG00000047932 "Golgi associated PDZ and coiled-coil motif containing" Q9HD26 6 117560269-117602542 "Cancer-related genes, Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019477, HPA024018" Approved Supported "Golgi apparatus,Calyx,Connecting piece,Mid piece,Principal piece" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" 60 "Golgi apparatus" "Calyx, Connecting piece, Mid piece, Principal piece" "HPA019477: , HPA024018: " "unprognostic (2.41e-1)" "unprognostic (9.23e-3)" "unprognostic (1.05e-1)" "unprognostic (6.93e-3)" "unprognostic (2.16e-1)" "unprognostic (1.28e-1)" "unprognostic (2.89e-2)" "unprognostic (3.71e-2)" "unprognostic (2.02e-1)" "unprognostic (9.80e-3)" "unprognostic (2.78e-3)" "unprognostic (1.88e-2)" "unprognostic (3.00e-1)" "unprognostic (2.86e-3)" "unprognostic (6.78e-2)" "unprognostic (9.55e-3)" "unprognostic (1.87e-1)" "unprognostic (1.46e-1)" "unprognostic (1.31e-1)" "unprognostic (2.19e-2)" "unprognostic (1.22e-3)" "unprognostic (1.62e-1)" "potential prognostic unfavorable (4.14e-4)" "unprognostic (6.55e-2)" "unprognostic (3.01e-2)" "unprognostic (2.31e-1)" "unprognostic (2.11e-1)" "unprognostic (5.72e-3)" "unprognostic (3.57e-1)" "unprognostic (2.20e-1)" "unprognostic (3.37e-2)" GORAB "FLJ11752, GO, NTKL-BP1, SCYL1BP1" ENSG00000120370 "Golgin, RAB6 interacting" Q5T7V8 1 170531819-170553834 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Dwarfism, Osteoporosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Pancreatic duct cells: 45.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027250, HPA027746" Approved Supported "Nucleoplasm,Nucleoli,Golgi apparatus,Cytosol" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 61: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 45: Non-specific - Nuclear processes" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 49 "Nucleoplasm, Golgi apparatus" "Nucleoli, Cytosol" "HPA027250: , HPA027746: " "unprognostic (1.09e-1)" "unprognostic (1.58e-1)" "unprognostic (3.58e-2)" "unprognostic (3.00e-2)" "unprognostic (7.95e-2)" "unprognostic (1.44e-1)" "unprognostic (1.45e-1)" "unprognostic (5.44e-2)" "unprognostic (1.38e-2)" "unprognostic (1.76e-2)" "unprognostic (2.06e-2)" "unprognostic (8.54e-2)" "potential prognostic unfavorable (3.66e-4)" "unprognostic (6.88e-2)" "unprognostic (5.78e-2)" "unprognostic (1.17e-1)" "unprognostic (3.79e-2)" "unprognostic (1.21e-1)" "unprognostic (1.81e-1)" "unprognostic (7.81e-2)" "unprognostic (9.60e-2)" "potential prognostic unfavorable (8.71e-4)" "unprognostic (2.15e-1)" "unprognostic (1.87e-1)" "unprognostic (3.02e-3)" "unprognostic (9.25e-2)" "unprognostic (3.29e-2)" "unprognostic (1.32e-1)" "unprognostic (2.30e-2)" "unprognostic (1.28e-1)" GORASP1 "FLJ23443, GOLPH5, GRASP65, P65" ENSG00000114745 "Golgi reassembly stacking protein 1" Q9BQQ3 3 39095222-39108369 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bergmann glia: 78.0;Early spermatids: 129.2;Late spermatids: 96.1" "Cell type enhanced" "Detected in all" "Bergmann glia: 82.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056283 Supported Supported "Golgi apparatus" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 19 "Golgi apparatus" "HPA056283: " "unprognostic (2.36e-1)" "unprognostic (1.90e-1)" "unprognostic (2.06e-1)" "unprognostic (3.39e-1)" "unprognostic (1.11e-1)" "unprognostic (1.96e-3)" "unprognostic (4.76e-1)" "unprognostic (3.34e-1)" "unprognostic (4.67e-2)" "unprognostic (1.90e-2)" "unprognostic (1.76e-2)" "unprognostic (1.19e-2)" "unprognostic (5.42e-3)" "potential prognostic unfavorable (7.00e-5)" "unprognostic (1.62e-1)" "unprognostic (2.45e-1)" "unprognostic (3.45e-2)" "unprognostic (1.37e-1)" "unprognostic (2.91e-1)" "unprognostic (7.46e-2)" "unprognostic (2.71e-1)" "unprognostic (2.51e-1)" "unprognostic (8.21e-2)" "unprognostic (3.19e-1)" "unprognostic (1.13e-1)" "unprognostic (4.83e-2)" "unprognostic (1.35e-1)" "unprognostic (3.57e-1)" "unprognostic (8.72e-2)" "unprognostic (3.52e-2)" "unprognostic (1.44e-2)" GORASP2 "GOLPH6, GRASP55, GRS2" ENSG00000115806 "Golgi reassembly stacking protein 2" Q9H8Y8 2 170928464-170967130 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 249.4;Late spermatids: 639.8;Syncytiotrophoblasts: 374.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035274, HPA035275, CAB075758" Enhanced Enhanced "Golgi apparatus" NA NA 560000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 70: Non-specific - Protein processing" "Cluster 27: Non-specific - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 235 "Golgi apparatus" "CAB075758: , HPA035274: , HPA035275: " "unprognostic (9.89e-3)" "unprognostic (1.22e-3)" "unprognostic (1.69e-2)" "potential prognostic unfavorable (2.84e-4)" "unprognostic (9.59e-2)" "unprognostic (2.64e-1)" "unprognostic (2.89e-1)" "unprognostic (1.46e-2)" "unprognostic (6.71e-2)" "unprognostic (1.06e-1)" "unprognostic (4.28e-2)" "unprognostic (1.68e-2)" "unprognostic (5.38e-3)" "potential prognostic unfavorable (3.45e-4)" "unprognostic (8.35e-3)" "unprognostic (2.09e-2)" "unprognostic (1.04e-2)" "unprognostic (1.92e-1)" "unprognostic (4.05e-2)" "unprognostic (2.06e-1)" "unprognostic (2.22e-1)" "unprognostic (7.92e-3)" "unprognostic (1.59e-3)" "unprognostic (2.26e-1)" "unprognostic (1.20e-1)" "unprognostic (1.25e-1)" "unprognostic (9.16e-2)" "unprognostic (1.30e-1)" "unprognostic (3.35e-1)" "unprognostic (3.80e-1)" "unprognostic (1.79e-1)" GOSR1 "GOLIM2, GOS-28, GOS28, GS28, P28" ENSG00000108587 "Golgi SNAP receptor complex member 1" O95249 17 30477362-30527592 "Predicted membrane proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020590 Uncertain NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 61: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 7: Non-specific - Transcription" 44 "HPA020590: " "unprognostic (2.40e-1)" "unprognostic (1.76e-2)" "unprognostic (1.32e-1)" "unprognostic (1.43e-2)" "unprognostic (4.96e-2)" "unprognostic (3.92e-2)" "unprognostic (2.52e-1)" "unprognostic (4.11e-2)" "unprognostic (1.19e-1)" "unprognostic (1.50e-2)" "validated prognostic favorable (1.85e-5)" "validated prognostic favorable (9.21e-4)" "unprognostic (2.34e-1)" "unprognostic (5.31e-3)" "unprognostic (1.94e-2)" "unprognostic (1.06e-2)" "potential prognostic unfavorable (8.50e-4)" "unprognostic (1.58e-1)" "unprognostic (1.94e-2)" "unprognostic (4.52e-2)" "unprognostic (6.26e-2)" "unprognostic (1.65e-1)" "unprognostic (6.46e-3)" "unprognostic (2.75e-1)" "unprognostic (1.43e-3)" "unprognostic (5.44e-2)" "unprognostic (3.29e-2)" "unprognostic (1.34e-1)" "unprognostic (3.10e-1)" "unprognostic (2.74e-2)" "unprognostic (1.01e-1)" GOSR2 "Bos1, GS27" ENSG00000108433 "Golgi SNAP receptor complex member 2" O14653 17 46923075-46975524 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Congenital muscular dystrophy, Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 29.3;Bergmann glia: 34.2;Brain excitatory neurons: 36.1;Brain inhibitory neurons: 37.6;Choroid plexus epithelial cells: 52.5;Early spermatids: 52.4;Ependymal cells: 20.0;Late spermatids: 146.5;Microglia: 36.0;Oligodendrocyte progenitor cells: 33.5;Oligodendrocytes: 40.3;Other brain neurons: 28.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Macrophages, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017456, HPA048956, HPA054472" Uncertain Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 67: Testis - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 22: Non-specific - Basic cellular functions" 69 "Nucleoplasm, Golgi apparatus" "CAB017456: , HPA048956: , HPA054472: " "unprognostic (2.37e-1)" "unprognostic (1.61e-2)" "unprognostic (1.99e-1)" "unprognostic (1.62e-2)" "unprognostic (4.75e-2)" "unprognostic (3.66e-2)" "unprognostic (1.98e-2)" "unprognostic (1.57e-1)" "unprognostic (2.77e-2)" "unprognostic (4.10e-3)" "unprognostic (8.82e-3)" "unprognostic (1.63e-2)" "unprognostic (2.25e-1)" "potential prognostic unfavorable (1.17e-4)" "unprognostic (2.04e-3)" "unprognostic (6.98e-2)" "unprognostic (1.70e-2)" "unprognostic (6.42e-2)" "unprognostic (2.43e-2)" "unprognostic (2.15e-2)" "potential prognostic unfavorable (1.13e-5)" "unprognostic (3.71e-2)" "potential prognostic unfavorable (5.82e-4)" "unprognostic (3.12e-1)" "unprognostic (2.61e-2)" "unprognostic (1.48e-1)" "unprognostic (7.87e-3)" "unprognostic (1.41e-1)" "unprognostic (2.77e-2)" "unprognostic (2.30e-2)" "unprognostic (7.34e-2)" GOT1 "AST, AST1, SGOT" ENSG00000120053 "Glutamic-oxaloacetic transaminase 1" P17174 10 99396870-99430624 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Amino-acid biosynthesis" "Aminotransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 478.6;skeletal muscle: 458.7;tongue: 944.6" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 304.7;Retinal ganglion cells: 239.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Skin - Eccrine sweat gland cells, Stomach - Parietal cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064532, HPA072629" Enhanced NA Yes 43000000 "Cluster 13: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cellular respiration" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 13: Non-specific - Mixed function" "Cluster 65: Non-specific - Cell growth & division" 8 "HPA064532: , HPA072629: " "unprognostic (3.62e-2)" "unprognostic (2.38e-3)" "unprognostic (2.23e-2)" "unprognostic (4.07e-3)" "unprognostic (2.09e-2)" "unprognostic (2.11e-1)" "unprognostic (1.69e-1)" "unprognostic (2.70e-2)" "unprognostic (1.38e-2)" "unprognostic (1.11e-2)" "validated prognostic favorable (1.47e-9)" "validated prognostic favorable (3.63e-4)" "unprognostic (2.20e-3)" "unprognostic (2.10e-2)" "potential prognostic favorable (1.28e-4)" "unprognostic (5.85e-3)" "unprognostic (1.28e-1)" "unprognostic (1.13e-1)" "unprognostic (2.10e-1)" "unprognostic (4.00e-2)" "unprognostic (1.99e-1)" "unprognostic (2.39e-2)" "unprognostic (1.16e-1)" "unprognostic (1.54e-1)" "unprognostic (1.64e-1)" "unprognostic (5.02e-2)" "unprognostic (2.34e-1)" "unprognostic (6.46e-3)" "unprognostic (9.78e-2)" "unprognostic (6.36e-3)" "unprognostic (2.62e-2)" GOT1L1 MGC33309 ENSG00000169154 "Glutamic-oxaloacetic transaminase 1 like 1" Q8NHS2 8 37934281-37940124 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Aminotransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 32 "testis: 13.3" "Group enriched" "Detected in some" 6 "Early spermatids: 92.0;Late primary spermatocytes: 83.0" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA028778 Uncertain NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 51: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" "HPA028778: " GOT2 "KAT4, KATIV, KYAT4, mitAAT" ENSG00000125166 "Glutamic-oxaloacetic transaminase 2" P00505 16 58707131-58734342 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Lipid transport, Transport" "Aminotransferase, Transferase" "Cancer-related genes, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "choroid plexus: 205.8;heart muscle: 297.9;liver: 300.5;skeletal muscle: 654.1;tongue: 678.6" "Cell type enhanced" "Detected in many" "Hepatocytes: 210.6;Retinal pigment epithelial cells: 294.1;Urothelial cells: 148.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018139, HPA058537" Enhanced NA NA 1900000 "Cluster 13: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cellular respiration" "Cluster 23: Choroid plexus - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" 4 "HPA018139: , HPA058537: " "unprognostic (7.70e-2)" "unprognostic (9.74e-3)" "unprognostic (1.83e-2)" "unprognostic (1.52e-1)" "unprognostic (2.55e-3)" "unprognostic (5.61e-3)" "unprognostic (2.92e-2)" "unprognostic (1.64e-1)" "potential prognostic unfavorable (9.35e-5)" "unprognostic (1.94e-1)" "potential prognostic favorable (1.20e-4)" "unprognostic (1.26e-1)" "potential prognostic favorable (8.34e-4)" "potential prognostic favorable (1.81e-4)" "unprognostic (4.08e-3)" "unprognostic (2.87e-3)" "unprognostic (1.12e-1)" "unprognostic (1.70e-1)" "unprognostic (2.40e-1)" "unprognostic (1.08e-1)" "unprognostic (1.38e-1)" "unprognostic (2.69e-1)" "unprognostic (2.15e-1)" "unprognostic (9.36e-2)" "unprognostic (1.66e-1)" "unprognostic (2.18e-2)" "unprognostic (7.55e-2)" "unprognostic (2.47e-1)" "unprognostic (1.94e-1)" "unprognostic (3.23e-2)" "unprognostic (1.09e-1)" GP1BA "CD42b, GP1B, GPIbalpha" ENSG00000185245 "Glycoprotein Ib platelet subunit alpha" P07359 17 4932277-4935023 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Blood coagulation, Cell adhesion, Hemostasis" "Bernard Soulier syndrome, Disease variant, von Willebrand disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.6;lymphoid tissue: 13.7" "Group enriched" "Detected in some" 28 "Megakaryocyte progenitors: 80.3;Megakaryocytes: 185.4;Platelets: 320.9" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 4.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 13 "basophil: 7.0" "Lineage enriched" "Detected in single" 44 "granulocytes: 7.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "CAB002496, HPA013316" Supported NA NA 480000000 "Cluster 4: Neutrophils - Degranulation" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 15: Non-specific - Transcription" "Cluster 47: Leukemia - Hemostasis" "Cluster 47: Platelets - Hemostasis" 10 "CAB002496: , HPA013316: " "unprognostic (4.33e-2)" "unprognostic (1.31e-1)" "unprognostic (2.68e-2)" "unprognostic (4.72e-2)" "unprognostic (5.93e-2)" "potential prognostic favorable (5.96e-4)" "unprognostic (6.28e-3)" "unprognostic (4.20e-3)" "unprognostic (4.10e-1)" GP1BB "CD42c, GPIbbeta" ENSG00000203618 "Glycoprotein Ib platelet subunit beta" P13224 22 19723539-19724771 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" "Blood coagulation, Cell adhesion, Hemostasis" "Bernard Soulier syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 92.5" "Cell type enhanced" "Detected in some" "Astrocytes: 15.4;Bergmann glia: 12.3;Brain excitatory neurons: 43.6;Brain inhibitory neurons: 59.1;Choroid plexus epithelial cells: 20.9;Ependymal cells: 18.3;Oligodendrocyte progenitor cells: 29.9;Oligodendrocytes: 18.2;Other brain neurons: 37.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 4.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 73.7;neutrophil: 74.7" "Lineage enriched" "Detected in many" 6 "granulocytes: 74.7" "Cancer enhanced" "Detected in single" "Leukemia: 3.0" "Colon - Enteric glia cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA 8400000 "Cluster 21: Neutrophils - Unknown function" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 35: Neurons - Synaptic function & neurogenesis" 5 "unprognostic (2.00e-1)" "unprognostic (1.85e-2)" "unprognostic (3.21e-2)" "unprognostic (1.66e-1)" "unprognostic (2.68e-1)" "unprognostic (6.95e-2)" "unprognostic (2.34e-1)" "unprognostic (5.27e-1)" "unprognostic (2.37e-2)" "unprognostic (2.55e-1)" "unprognostic (2.62e-1)" GP2 ZAP75 ENSG00000169347 "Glycoprotein 2" P55259 16 20309574-20327808 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 968 "pancreas: 33354.1" "Cell type enriched" "Detected in some" 39 "Pancreatic acinar cells: 20522.0" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 11 "Pancreatic Adenocarcinoma (TCGA): 680.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 4.4" "Kidney - Ascending Loop of Henle cells, Prostate - Prostate glandular cells" "Not detected" "Not detected" "Region enriched" "Detected in single" 10 "midbrain: 1.0" "HPA015739, HPA016668" Enhanced "Secreted to digestive system" Receptor NA NA 58000 "Cluster 8: Pancreas - Proteolysis" "Cluster 48: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 5: Pancreatic acinar cells - Pancreatic exocrine secretion" "HPA015739: , HPA016668: " "unprognostic (1.40e-1)" "unprognostic (5.82e-2)" "unprognostic (8.46e-2)" "unprognostic (1.86e-1)" "unprognostic (6.59e-3)" "unprognostic (7.88e-2)" "unprognostic (1.24e-2)" "unprognostic (1.52e-1)" "unprognostic (6.42e-2)" "unprognostic (3.67e-2)" "unprognostic (1.65e-1)" "unprognostic (3.13e-1)" "unprognostic (1.71e-1)" "unprognostic (1.50e-1)" "unprognostic (8.71e-2)" "unprognostic (9.64e-3)" "unprognostic (2.04e-1)" "unprognostic (4.20e-2)" GP5 CD42d ENSG00000178732 "Glycoprotein V platelet" P40197 3 194394821-194399266 "CD markers, Plasma proteins, Predicted membrane proteins" "Blood coagulation, Cell adhesion, Hemostasis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.0" "Group enriched" "Detected in some" 6 "Megakaryocytes: 18.5;Platelets: 25.3" "Cell type enriched" "Detected in single" 21 "ependymal cell: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 8 "Leukemia: 1.2" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA072646 Approved Cytosol NA NA 200000000 "Cluster 18: Lymphoid tissue - Immune response" "Cluster 6: Leukemia - Signal transduction" "Cluster 47: Platelets - Hemostasis" 34 Cytosol "HPA072646: " GP6 GPVI ENSG00000088053 "Glycoprotein VI platelet" Q9HCN6 19 55013705-55038264 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Blood coagulation, Hemostasis" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.3;testis: 2.5" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 8.7;Brain inhibitory neurons: 8.6;Distal convoluted tubule cells: 6.7;Loop of henle epithelial cells: 5.8;Other brain neurons: 6.2;Papillary tip epithelial cells: 12.8;Platelets: 15.5;Renal collecting duct intercalated cells: 7.6;Renal collecting duct principal cells: 8.4;Renal connecting tubule cells: 9.7" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Leukemia: 1.3" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA047611, HPA066482" Approved Supported "Plasma membrane" "Intracellular and membrane" "Blood coagulation" NA NA 8300000 "Cluster 35: Neutrophils - Protein binding" "Cluster 67: Testis - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 102: Non-specific - Mixed function" 5 "Plasma membrane" "HPA047611: , HPA066482: " "unprognostic (8.92e-3)" GP9 "CD42a, GPIX" ENSG00000169704 "Glycoprotein IX platelet" P14770 3 129060779-129062406 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" "Blood coagulation, Cell adhesion, Hemostasis" "Bernard Soulier syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.8;lung: 3.2;lymphoid tissue: 8.8" "Cell type enriched" "Detected in some" 4 "Platelets: 3990.4" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "choroid plexus: 1.3" "Group enriched" "Detected in some" 7 "basophil: 29.4;neutrophil: 14.0" "Lineage enriched" "Detected in many" 10 "granulocytes: 29.4" "Cancer enriched" "Detected in single" 97 "Leukemia: 9.6" "Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA063182 Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 4700000 "Cluster 4: Neutrophils - Degranulation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 23: Choroid plexus - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 47: Platelets - Hemostasis" 57 "Plasma membrane, Cytosol" Nucleoplasm "HPA063182: " GPA33 A33 ENSG00000143167 "Glycoprotein A33" Q99795 1 167052836-167166479 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "intestine: 202.4" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 797.4;Colonocytes: 636.1;Enteric stem cells: 78.6;Enteric transient amplifying cells: 131.0;Enterocytes: 297.1;Goblet cells: 292.6;Myonuclei: 87.3;Tuft cells: 80.7" "Cell type enriched" "Detected in many" 4 "choroid plexus epithelial cell: 21.7" "Group enriched" "Detected in some" 5 "Colon Adenocarcinoma (TCGA): 122.6;Rectum Adenocarcinoma (TCGA): 110.1" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 24.3;T-reg: 19.6" "Lineage enriched" "Detected in many" 6 "T-cells: 24.3" "Cancer enhanced" "Detected in some" "Bile duct cancer: 34.1;colorectal cancer: 100.5" "Colon - Colon enterocytes, Pituitary gland - Corticotropes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018858, CAB025943" Enhanced NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 77: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 9 "CAB025943: , HPA018858: " "unprognostic (1.17e-3)" "unprognostic (5.35e-3)" "unprognostic (4.36e-2)" "potential prognostic favorable (7.69e-5)" "unprognostic (1.59e-1)" "unprognostic (8.34e-2)" "unprognostic (1.19e-2)" "unprognostic (2.69e-2)" "unprognostic (5.75e-3)" "unprognostic (1.72e-2)" "unprognostic (1.78e-2)" GPAA1 "GAA1, hGAA1" ENSG00000197858 "Glycosylphosphatidylinositol anchor attachment 1" O43292 8 144082337-144093149 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early primary spermatocytes: 257.4;Extravillous trophoblasts: 196.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077224 Approved Approved "Endoplasmic reticulum,Centrosome,Mitochondria,Cytosol" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 40: Non-specific - Unknown function" "Cluster 3: Early primary spermatocytes - Early meiosis" 30 "Endoplasmic reticulum, Cytosol" "Centrosome, Mitochondria" "HPA077224: " "unprognostic (1.63e-2)" "potential prognostic unfavorable (4.02e-4)" "unprognostic (2.01e-1)" "unprognostic (1.20e-2)" "unprognostic (2.20e-1)" "unprognostic (2.24e-1)" "unprognostic (1.44e-1)" "unprognostic (2.02e-2)" "unprognostic (3.31e-1)" "unprognostic (6.82e-2)" "unprognostic (6.86e-2)" "unprognostic (1.72e-1)" "unprognostic (3.86e-1)" "unprognostic (3.64e-3)" "unprognostic (3.16e-2)" "unprognostic (4.52e-2)" "unprognostic (3.02e-2)" "unprognostic (4.55e-2)" "unprognostic (2.52e-1)" "unprognostic (1.09e-1)" "potential prognostic favorable (6.18e-4)" "unprognostic (5.60e-2)" "unprognostic (4.21e-3)" "unprognostic (5.78e-2)" "unprognostic (1.82e-1)" "unprognostic (2.74e-2)" "unprognostic (2.63e-1)" "unprognostic (7.80e-2)" "unprognostic (1.10e-1)" "unprognostic (1.76e-1)" "unprognostic (4.23e-2)" GPALPP1 "AD029, bA245H20.2, KIAA1704, LSR7" ENSG00000133114 "GPALPP motifs containing 1" Q8IXQ4 13 44989529-45037669 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA038966, HPA058739" Enhanced Approved "Nucleoplasm,Nucleoli rim" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 40: Non-specific - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 19: Non-specific - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" 3 "Nucleoli rim" Nucleoplasm "HPA038966: , HPA058739: " "unprognostic (1.31e-1)" "unprognostic (3.02e-1)" "unprognostic (3.86e-2)" "unprognostic (1.40e-1)" "unprognostic (1.51e-1)" "unprognostic (2.74e-1)" "unprognostic (4.07e-1)" "unprognostic (1.41e-1)" "unprognostic (3.41e-3)" "unprognostic (1.15e-2)" "potential prognostic favorable (1.74e-4)" "unprognostic (3.91e-1)" "unprognostic (1.06e-1)" "unprognostic (1.20e-2)" "unprognostic (2.11e-1)" "unprognostic (2.70e-2)" "unprognostic (1.05e-1)" "unprognostic (2.37e-3)" "unprognostic (2.29e-3)" "unprognostic (4.67e-1)" "unprognostic (2.42e-3)" "unprognostic (2.81e-1)" "unprognostic (1.43e-3)" "unprognostic (1.43e-1)" "unprognostic (1.33e-1)" "unprognostic (1.38e-1)" "unprognostic (1.48e-1)" "unprognostic (1.22e-1)" "unprognostic (1.35e-1)" GPAM "GPAT1, KIAA1560, MGC26846" ENSG00000119927 "Glycerol-3-phosphate acyltransferase, mitochondrial" Q9HCL2 10 112149865-112215377 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 287.2;liver: 134.8" "Cell type enriched" "Detected in many" 7 "Adipocytes: 1999.4" "Cell type enriched" "Detected in all" 6 "astrocyte: 128.7" "Cancer enriched" "Detected in all" 4 "Liver Hepatocellular Carcinoma (TCGA): 37.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Liver - Hepatocytes, Minor Salivary Gland - Adipocytes (Minor salivary gland), Skin - Adipocytes (Skin), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046339, HPA060090" Approved Approved Mitochondria NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 89: Adipocytes - Lipid metabolism" 3 Mitochondria "HPA046339: , HPA060090: " "unprognostic (1.83e-2)" "unprognostic (2.10e-1)" "unprognostic (1.68e-2)" "unprognostic (1.50e-2)" "unprognostic (2.84e-1)" "unprognostic (1.33e-1)" "unprognostic (1.16e-1)" "unprognostic (4.19e-2)" "unprognostic (9.73e-2)" "unprognostic (6.89e-2)" "potential prognostic favorable (3.68e-5)" "unprognostic (3.96e-2)" "unprognostic (1.84e-1)" "unprognostic (3.37e-2)" "unprognostic (8.20e-3)" "unprognostic (2.39e-2)" "unprognostic (2.13e-1)" "unprognostic (8.35e-2)" "unprognostic (7.52e-3)" "unprognostic (4.21e-2)" "unprognostic (1.64e-3)" "unprognostic (2.06e-2)" "unprognostic (1.57e-1)" "unprognostic (8.23e-2)" "unprognostic (5.25e-2)" "unprognostic (1.90e-1)" "unprognostic (2.79e-1)" "unprognostic (3.17e-1)" "unprognostic (7.17e-2)" "unprognostic (5.65e-2)" "unprognostic (2.27e-1)" GPANK1 "ANKRD59, BAT4, D6S54E, G5, GPATCH10" ENSG00000204438 "G-patch domain and ankyrin repeats 1" O95872 6 31661228-31666283 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 28.7;Early primary spermatocytes: 61.9;Late primary spermatocytes: 95.8;Late spermatids: 28.1;Oocytes: 41.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006301 Approved Approved "Endoplasmic reticulum" NA Yes "Cluster 21: Neutrophils - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 37: Neurons - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 69 "Endoplasmic reticulum" "HPA006301: " "unprognostic (3.73e-2)" "unprognostic (2.13e-1)" "unprognostic (7.92e-2)" "unprognostic (5.53e-2)" "unprognostic (6.45e-2)" "unprognostic (2.34e-2)" "unprognostic (6.08e-3)" "potential prognostic favorable (6.47e-4)" "unprognostic (9.90e-2)" "unprognostic (1.15e-3)" "unprognostic (1.13e-2)" "unprognostic (3.70e-2)" "potential prognostic unfavorable (9.20e-4)" "unprognostic (5.46e-3)" "unprognostic (6.45e-2)" "unprognostic (1.98e-1)" "unprognostic (8.36e-2)" "unprognostic (6.69e-2)" "unprognostic (4.01e-1)" "unprognostic (3.29e-1)" "unprognostic (5.63e-2)" "unprognostic (3.76e-2)" "unprognostic (7.33e-3)" "unprognostic (1.28e-2)" "unprognostic (3.98e-2)" "unprognostic (9.90e-2)" "unprognostic (1.15e-1)" "unprognostic (2.17e-1)" "unprognostic (3.32e-3)" "unprognostic (6.81e-2)" GPAT2 CT123 ENSG00000186281 "Glycerol-3-phosphate acyltransferase 2, mitochondrial" Q6NUI2 2 96021946-96039451 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 7 "Breast lactating cells: 595.8" "Cell type enhanced" "Detected in some" "eccentric medium spiny neuron: 2.7;medium spiny neuron: 3.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "naive B-cell: 4.1" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Bladder cancer: 17.6" "Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA036841 Uncertain Approved Mitochondria NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 4: Non-specific - Transcription" "Cluster 4: Breast lactating luminal cells - Lactation" Mitochondria "HPA036841: " "unprognostic (4.33e-3)" "unprognostic (1.53e-2)" "unprognostic (1.51e-1)" "unprognostic (9.59e-3)" "unprognostic (1.78e-1)" "unprognostic (1.71e-1)" "unprognostic (1.47e-1)" "unprognostic (1.83e-1)" "unprognostic (7.75e-2)" "unprognostic (7.70e-2)" "unprognostic (2.90e-2)" "unprognostic (5.98e-2)" "unprognostic (1.18e-2)" "unprognostic (4.38e-3)" "unprognostic (3.78e-1)" "unprognostic (5.83e-2)" "unprognostic (1.55e-1)" "unprognostic (3.14e-2)" "unprognostic (2.62e-2)" "unprognostic (8.51e-2)" "unprognostic (1.67e-2)" "unprognostic (1.51e-1)" "unprognostic (1.46e-1)" GPAT3 "AGPAT10, AGPAT9, HMFN0839, LPAAT-theta, MAG1, MGC11324" ENSG00000138678 "Glycerol-3-phosphate acyltransferase 3" Q53EU6 4 83535914-83605875 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 82.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 281.0;cDC: 786.7;Distal convoluted tubule cells: 398.2;Mast cells: 331.5;Myonuclei: 260.9;Neutrophils: 315.1;Renal collecting duct intercalated cells: 731.3" "Cell type enhanced" "Detected in many" "lower rhombic lip: 99.4" "Cancer enriched" "Detected in many" 4 "Kidney Chromophobe (TCGA): 61.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 183.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Spleen - Neutrophils_2, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA029414 Approved NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 76: Non-specific - Metabolism" "Cluster 45: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 82: Dendritic cells - Antigen presentation" 19 "HPA029414: " "unprognostic (3.41e-1)" "unprognostic (6.25e-2)" "unprognostic (1.14e-2)" "unprognostic (1.20e-1)" "unprognostic (8.58e-2)" "unprognostic (6.39e-2)" "unprognostic (3.60e-2)" "unprognostic (7.54e-2)" "potential prognostic favorable (7.21e-9)" "unprognostic (2.07e-3)" "unprognostic (1.23e-1)" "unprognostic (2.65e-1)" "unprognostic (5.05e-3)" "unprognostic (1.63e-2)" "unprognostic (2.05e-1)" "unprognostic (1.20e-1)" "unprognostic (5.02e-3)" "unprognostic (2.56e-1)" "unprognostic (1.85e-1)" "unprognostic (1.80e-2)" "unprognostic (2.73e-1)" "unprognostic (2.26e-1)" "unprognostic (1.65e-2)" "unprognostic (1.37e-2)" "unprognostic (5.25e-1)" "unprognostic (6.77e-3)" "potential prognostic unfavorable (2.05e-4)" "unprognostic (1.93e-2)" GPAT4 "AGPAT6, DKFZp586M1819, LPAAT-zeta, TSARG7" ENSG00000158669 "Glycerol-3-phosphate acyltransferase 4" Q86UL3 8 41577187-41625001 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 385.0;Neutrophils: 249.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016471 Approved NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 35 "HPA016471: " "unprognostic (9.02e-2)" "unprognostic (6.17e-3)" "unprognostic (7.85e-2)" "unprognostic (1.74e-2)" "unprognostic (3.85e-3)" "unprognostic (3.03e-1)" "potential prognostic favorable (1.34e-4)" "unprognostic (3.20e-3)" "unprognostic (7.24e-3)" "potential prognostic favorable (1.96e-4)" "unprognostic (9.63e-2)" "unprognostic (1.34e-2)" "unprognostic (7.17e-2)" "unprognostic (7.63e-2)" "unprognostic (2.38e-2)" "unprognostic (2.51e-1)" "unprognostic (1.55e-2)" "unprognostic (2.66e-3)" "unprognostic (1.07e-1)" "unprognostic (6.76e-2)" "unprognostic (1.45e-1)" "unprognostic (2.01e-2)" "unprognostic (6.18e-3)" "unprognostic (2.79e-2)" "unprognostic (7.29e-2)" "unprognostic (1.06e-1)" "unprognostic (1.37e-1)" "unprognostic (1.04e-1)" "unprognostic (4.91e-2)" GPATCH1 "ECGP, FLJ10206, FLJ38686, GPATC1" ENSG00000076650 "G-patch domain containing 1" Q9BRR8 19 33080899-33130542 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043430, HPA043604" Approved Approved "Nucleoplasm,Primary cilium,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 61: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 68: Foveolar cells - Mucosal defense" 18 Nucleoplasm "Primary cilium, Cytosol" "HPA043430: , HPA043604: " "unprognostic (4.58e-2)" "unprognostic (3.71e-1)" "unprognostic (1.85e-1)" "unprognostic (4.99e-2)" "unprognostic (4.32e-1)" "unprognostic (1.35e-1)" "unprognostic (1.19e-1)" "unprognostic (1.75e-1)" "unprognostic (4.97e-2)" "unprognostic (6.51e-2)" "potential prognostic favorable (6.04e-7)" "unprognostic (4.59e-3)" "unprognostic (7.81e-2)" "unprognostic (7.08e-2)" "unprognostic (6.95e-2)" "unprognostic (5.08e-2)" "unprognostic (2.03e-1)" "unprognostic (3.61e-3)" "unprognostic (1.51e-2)" "unprognostic (9.71e-2)" "unprognostic (2.86e-1)" "unprognostic (3.61e-1)" "unprognostic (7.30e-3)" "unprognostic (5.79e-2)" "potential prognostic favorable (5.75e-4)" "unprognostic (3.23e-2)" "unprognostic (2.85e-1)" "unprognostic (4.06e-2)" "unprognostic (2.50e-1)" "unprognostic (1.60e-2)" "unprognostic (2.39e-3)" GPATCH11 "CCDC75, CENP-Y, CENPY, FLJ38348" ENSG00000152133 "G-patch domain containing 11" 2 37084518-37099244 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 106.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038231, HPA038232" Enhanced Supported Nucleoplasm NA NA "Cluster 41: Basophils - Unknown function" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 17: Non-specific - RNA processing" 28 Nucleoplasm "HPA038231: , HPA038232: " "unprognostic (6.93e-2)" "unprognostic (1.55e-2)" "unprognostic (2.95e-1)" "unprognostic (3.54e-2)" "unprognostic (1.94e-1)" "unprognostic (1.25e-1)" "unprognostic (2.94e-2)" "unprognostic (4.09e-2)" "unprognostic (1.44e-2)" "potential prognostic favorable (2.82e-5)" "unprognostic (1.86e-1)" "unprognostic (1.84e-2)" "unprognostic (3.13e-3)" "unprognostic (6.31e-2)" "unprognostic (9.33e-2)" "unprognostic (1.71e-1)" "unprognostic (2.67e-1)" "unprognostic (2.06e-2)" "unprognostic (2.04e-3)" "unprognostic (2.10e-1)" "unprognostic (2.33e-3)" "unprognostic (3.65e-2)" "unprognostic (1.93e-1)" "unprognostic (9.96e-2)" "unprognostic (2.32e-2)" "unprognostic (1.58e-1)" "unprognostic (2.24e-1)" "unprognostic (2.35e-2)" "unprognostic (5.15e-1)" GPATCH2 "CT110, FLJ10252, GPATC2, Pfa1, PPP1R30" ENSG00000092978 "G-patch domain containing 2" Q9NW75 1 217426992-217631090 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 319.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027181, HPA027322" Uncertain Supported "Nuclear speckles" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 23: Choroid plexus - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 12 "Nuclear speckles" "HPA027181: , HPA027322: " "unprognostic (3.46e-1)" "unprognostic (1.03e-1)" "unprognostic (2.51e-1)" "unprognostic (6.03e-2)" "unprognostic (3.15e-1)" "unprognostic (1.86e-1)" "unprognostic (1.83e-1)" "unprognostic (9.89e-2)" "unprognostic (2.27e-1)" "unprognostic (1.28e-2)" "unprognostic (1.46e-2)" "unprognostic (6.67e-2)" "potential prognostic unfavorable (1.57e-4)" "unprognostic (2.85e-2)" "unprognostic (2.24e-1)" "unprognostic (6.98e-2)" "unprognostic (8.18e-3)" "unprognostic (1.99e-1)" "unprognostic (1.69e-1)" "unprognostic (5.44e-2)" "unprognostic (1.10e-3)" "unprognostic (3.26e-2)" "unprognostic (1.25e-2)" "unprognostic (4.76e-2)" "unprognostic (8.71e-3)" "unprognostic (8.34e-2)" "unprognostic (7.35e-2)" "unprognostic (7.37e-2)" "unprognostic (1.67e-1)" "unprognostic (2.92e-3)" "unprognostic (2.72e-2)" GPATCH2L "C14orf118, FLJ10033, FLJ20689" ENSG00000089916 "G-patch domain containing 2 like" Q9NWQ4 14 76151916-76254342 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018856 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 41: Basophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 30 Nucleoplasm Cytosol "HPA018856: " "unprognostic (2.21e-1)" "unprognostic (2.45e-1)" "unprognostic (5.51e-2)" "unprognostic (2.20e-2)" "unprognostic (3.98e-1)" "unprognostic (1.60e-1)" "potential prognostic favorable (8.08e-4)" "unprognostic (5.77e-2)" "potential prognostic unfavorable (2.71e-5)" "unprognostic (1.18e-3)" "unprognostic (2.05e-2)" "unprognostic (2.05e-1)" "unprognostic (5.16e-2)" "unprognostic (2.24e-1)" "unprognostic (6.78e-3)" "unprognostic (1.20e-1)" "unprognostic (1.79e-1)" "unprognostic (3.10e-2)" "unprognostic (5.09e-3)" "unprognostic (5.92e-2)" "unprognostic (1.76e-3)" "unprognostic (1.57e-3)" "unprognostic (4.77e-2)" "unprognostic (4.00e-3)" "unprognostic (2.53e-2)" "unprognostic (6.16e-2)" "unprognostic (1.95e-1)" "unprognostic (7.28e-2)" "unprognostic (1.82e-1)" GPATCH3 "FLJ12455, GPATC3" ENSG00000198746 "G-patch domain containing 3" Q96I76 1 26890488-26900467 "Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Disease variant, Glaucoma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 43.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032078, HPA054973" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 24: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 65: Non-specific - Cell growth & division" Nucleoplasm Cytosol "HPA032078: , HPA054973: " "unprognostic (3.05e-1)" "unprognostic (3.46e-2)" "unprognostic (2.28e-1)" "unprognostic (2.24e-1)" "unprognostic (2.87e-1)" "unprognostic (8.17e-3)" "unprognostic (1.94e-1)" "potential prognostic favorable (1.46e-4)" "unprognostic (4.44e-2)" "unprognostic (1.58e-1)" "potential prognostic favorable (1.63e-4)" "unprognostic (2.78e-3)" "unprognostic (3.09e-2)" "validated prognostic unfavorable (1.08e-5)" "validated prognostic unfavorable (6.99e-4)" "unprognostic (1.36e-2)" "unprognostic (2.18e-1)" "unprognostic (4.12e-2)" "unprognostic (1.22e-1)" "unprognostic (6.71e-2)" "unprognostic (4.70e-3)" "unprognostic (9.30e-3)" "unprognostic (1.47e-1)" "unprognostic (1.33e-1)" "unprognostic (9.48e-2)" "unprognostic (6.52e-2)" "unprognostic (5.97e-2)" "unprognostic (5.10e-2)" "unprognostic (5.62e-3)" "unprognostic (9.63e-2)" "unprognostic (9.12e-3)" GPATCH4 "DKFZP434F1735, FLJ20249, GPATC4" ENSG00000160818 "G-patch domain containing 4 (gene/pseudogene)" 1 156594301-156601496 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 65.1" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 122.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028323, HPA054319" Approved Enhanced Nucleoplasm,Nucleoli NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 45: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 15 Nucleoli Nucleoplasm "HPA028323: , HPA054319: " "unprognostic (3.65e-2)" "unprognostic (6.84e-2)" "unprognostic (2.20e-1)" "unprognostic (1.09e-3)" "unprognostic (2.37e-1)" "unprognostic (8.67e-2)" "unprognostic (1.07e-2)" "unprognostic (1.35e-2)" "unprognostic (2.87e-3)" "potential prognostic unfavorable (2.39e-5)" "unprognostic (8.34e-3)" "unprognostic (1.71e-1)" "unprognostic (1.33e-1)" "potential prognostic unfavorable (3.73e-5)" "unprognostic (2.78e-3)" "unprognostic (6.12e-3)" "unprognostic (8.98e-3)" "unprognostic (4.81e-2)" "unprognostic (5.44e-2)" "unprognostic (1.48e-1)" "unprognostic (6.80e-2)" "unprognostic (5.59e-2)" "unprognostic (7.60e-2)" "unprognostic (2.03e-3)" "unprognostic (6.33e-2)" "unprognostic (1.17e-1)" "unprognostic (5.23e-3)" "unprognostic (9.88e-3)" "unprognostic (2.72e-1)" "unprognostic (7.72e-2)" "unprognostic (4.56e-3)" GPATCH8 "GPATC8, KIAA0553" ENSG00000186566 "G-patch domain containing 8" Q9UKJ3 17 44395281-44503430 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Myonuclei: 1703.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044380 Approved Approved "Nuclear speckles,Mitochondria" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 24: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 8 "Nuclear speckles" Mitochondria "HPA044380: " "unprognostic (6.82e-3)" "unprognostic (6.98e-2)" "unprognostic (1.24e-1)" "unprognostic (7.33e-3)" "unprognostic (3.23e-1)" "unprognostic (1.04e-2)" "unprognostic (3.41e-2)" "unprognostic (1.81e-1)" "unprognostic (9.34e-2)" "unprognostic (5.70e-3)" "potential prognostic favorable (8.50e-4)" "unprognostic (4.73e-3)" "unprognostic (2.44e-1)" "unprognostic (1.79e-2)" "unprognostic (9.23e-2)" "unprognostic (9.51e-2)" "unprognostic (2.16e-2)" "unprognostic (2.54e-1)" "unprognostic (2.89e-2)" "unprognostic (5.25e-3)" "unprognostic (2.66e-2)" "unprognostic (3.07e-2)" "unprognostic (1.17e-3)" "unprognostic (9.72e-2)" "unprognostic (9.98e-3)" "unprognostic (1.32e-1)" "unprognostic (1.60e-1)" "unprognostic (2.71e-1)" "unprognostic (1.74e-1)" "unprognostic (7.49e-3)" "unprognostic (8.01e-2)" GPBAR1 "BG37, GPCR, GPCR19, GPR131, M-BAR, MGC40597, TGR5" ENSG00000179921 "G protein-coupled bile acid receptor 1" Q8TDU6 2 218259496-218263861 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 29.9;breast: 17.3;gallbladder: 16.3" "Cell type enhanced" "Detected in some" "Decidual stromal cells: 169.4;Early spermatids: 12.3;Endometrial stromal cells: 12.4;Hofbauer cells: 22.9;Kupffer cells: 60.5;monocytes: 31.3;Neuroendocrine cells: 45.2" "Cell type enriched" "Detected in single" 12 "leukocyte: 5.6" "Cancer enhanced" "Detected in many" "Pancreatic Adenocarcinoma (TCGA): 9.5" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 4 "classical monocyte: 288.5;intermediate monocyte: 712.6;non-classical monocyte: 698.6" "Lineage enriched" "Detected in many" 5 "monocytes: 712.6" "Group enriched" "Detected in some" 5 "lymphoma: 2.0;Neuroblastoma: 2.2;Rhabdoid: 5.9" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Macrophages, Breast - Adipocytes (Breast), Skeletal muscle - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA062890 Enhanced NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 15: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 23 "HPA062890: " "unprognostic (1.35e-1)" "unprognostic (1.32e-2)" "unprognostic (2.49e-2)" "unprognostic (1.94e-1)" "unprognostic (1.84e-1)" "unprognostic (1.01e-1)" "unprognostic (1.14e-1)" "unprognostic (9.05e-2)" "unprognostic (2.89e-1)" "unprognostic (2.06e-2)" "unprognostic (1.71e-2)" "unprognostic (2.48e-3)" "unprognostic (2.69e-1)" "unprognostic (2.35e-2)" "unprognostic (1.73e-2)" "unprognostic (8.44e-2)" GPBP1 DKFZp761C169 ENSG00000062194 "GC-rich promoter binding protein 1" Q86WP2 5 57173948-57264679 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 956.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037773 Approved Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 15 "Vesicles, Cytosol" "Plasma membrane" "HPA037773: " "unprognostic (9.69e-3)" "unprognostic (4.06e-2)" "unprognostic (2.44e-1)" "unprognostic (5.41e-2)" "unprognostic (2.67e-2)" "unprognostic (1.23e-1)" "unprognostic (5.85e-2)" "unprognostic (2.94e-2)" "unprognostic (9.20e-2)" "unprognostic (3.52e-3)" "validated prognostic favorable (2.11e-6)" "validated prognostic favorable (3.64e-4)" "unprognostic (2.30e-2)" "unprognostic (2.90e-2)" "unprognostic (1.81e-1)" "unprognostic (3.83e-1)" "unprognostic (2.33e-2)" "unprognostic (1.03e-1)" "unprognostic (1.70e-1)" "unprognostic (2.24e-1)" "unprognostic (1.59e-1)" "unprognostic (2.89e-1)" "unprognostic (2.87e-3)" "unprognostic (4.58e-2)" "unprognostic (3.54e-1)" "unprognostic (1.03e-1)" "unprognostic (3.08e-3)" "unprognostic (3.07e-1)" "unprognostic (1.36e-1)" "unprognostic (3.18e-2)" "unprognostic (9.23e-2)" GPBP1L1 SP192 ENSG00000159592 "GC-rich promoter binding protein 1 like 1" Q9HC44 1 45627304-45688113 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028593 Approved Approved "Nucleoplasm,Plasma membrane,Focal adhesion sites,Cytosol" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 37 Nucleoplasm "Plasma membrane, Focal adhesion sites, Cytosol" "HPA028593: " "unprognostic (1.01e-2)" "unprognostic (6.40e-2)" "unprognostic (6.35e-3)" "unprognostic (1.01e-2)" "potential prognostic favorable (8.39e-5)" "unprognostic (3.32e-1)" "unprognostic (1.51e-1)" "unprognostic (3.66e-2)" "unprognostic (1.17e-2)" "unprognostic (2.69e-2)" "validated prognostic favorable (1.03e-5)" "validated prognostic favorable (2.35e-4)" "unprognostic (1.15e-1)" "potential prognostic unfavorable (1.97e-4)" "unprognostic (2.72e-1)" "unprognostic (3.33e-1)" "unprognostic (3.72e-1)" "unprognostic (9.56e-2)" "unprognostic (1.00e-1)" "unprognostic (6.54e-2)" "unprognostic (1.39e-1)" "unprognostic (5.39e-3)" "unprognostic (1.15e-1)" "unprognostic (2.93e-1)" "unprognostic (2.76e-2)" "unprognostic (7.40e-2)" "unprognostic (2.08e-1)" "unprognostic (1.21e-1)" "unprognostic (1.78e-1)" "unprognostic (1.63e-1)" "unprognostic (4.68e-2)" GPC1 glypican ENSG00000063660 "Glypican 1" P35052 2 240435663-240468076 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 213.4" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 107.1;Esophageal basal cells: 101.9;Extravillous trophoblasts: 285.2;Schwann cells: 104.4;Syncytiotrophoblasts: 115.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 382.6" "Colon - Enteric glia cells, Minor Salivary Gland - Minor salivary gland basal cells, Pituitary gland - Corticotropes, Spleen - Fibroblasts_1, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030571 Supported "Plasma membrane,Cytosol" "Intracellular and membrane" "No annotated function" NA NA 5400000 "Cluster 24: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 32 "Plasma membrane, Cytosol" "HPA030571: " "unprognostic (5.34e-2)" "unprognostic (7.75e-2)" "unprognostic (1.94e-2)" "unprognostic (8.84e-2)" "unprognostic (1.06e-2)" "unprognostic (1.74e-2)" "unprognostic (5.50e-2)" "unprognostic (9.31e-2)" "unprognostic (2.33e-2)" "unprognostic (2.24e-1)" "unprognostic (1.27e-2)" "potential prognostic unfavorable (3.26e-4)" "unprognostic (1.28e-2)" "potential prognostic unfavorable (3.79e-6)" "unprognostic (1.44e-2)" "potential prognostic unfavorable (2.87e-4)" "unprognostic (2.80e-1)" "unprognostic (2.94e-1)" "unprognostic (5.63e-2)" "unprognostic (1.79e-2)" "unprognostic (2.50e-2)" "unprognostic (6.25e-2)" "unprognostic (2.98e-1)" "unprognostic (3.93e-1)" "unprognostic (5.75e-2)" "unprognostic (7.93e-3)" "unprognostic (8.22e-2)" "unprognostic (3.47e-2)" "unprognostic (1.35e-2)" "unprognostic (1.07e-3)" "unprognostic (1.99e-3)" GPC2 "cerebroglycan, DKFZp547M109, FLJ38962" ENSG00000213420 "Glypican 2" Q8N158 7 100169606-100177381 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 4.8;skin 1: 5.5;testis: 11.4" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 8.6;Early primary spermatocytes: 11.2;Early spermatids: 42.3;Late primary spermatocytes: 13.5;Late spermatids: 7.7;Microglia: 6.4;Neuroendocrine cells: 6.3;Oligodendrocyte progenitor cells: 17.5;Thymocytes: 9.3" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 8.4;oligodendrocyte precursor cell: 16.6" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 13.0;Testicular Germ Cell Tumor (TCGA): 8.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Neuroblastoma: 45.6" "Spleen - B-cells (Spleen), Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" CAB025423 Uncertain "Intracellular and membrane" "No annotated function" NA NA "Cluster 47: Testis - Mixed function" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" "CAB025423: " "unprognostic (7.38e-2)" "unprognostic (1.23e-1)" "unprognostic (1.93e-1)" "unprognostic (2.60e-2)" "unprognostic (5.12e-2)" "unprognostic (4.12e-3)" "unprognostic (1.16e-1)" "unprognostic (1.30e-1)" "unprognostic (1.82e-1)" "unprognostic (1.04e-1)" "unprognostic (1.43e-1)" "unprognostic (9.98e-3)" "unprognostic (8.33e-3)" "unprognostic (2.50e-2)" "unprognostic (1.38e-1)" GPC3 "DGSX, OCI-5, SDYS, SGB, SGBS, SGBS1" ENSG00000147257 "Glypican 3" P51654 X 133535745-133987100 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted membrane proteins" "Protease inhibitor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "placenta: 669.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 103.0;Epididymal basal cells: 99.6;Extravillous trophoblasts: 130.2;Fibro-adipogenic progenitors: 162.9;Fibroblasts: 326.8;Müller glia: 124.5;Parietal cells: 134.4;Pericytes: 105.5;Pituicytes/FSCs: 224.9;Pituitary stem cells: 798.7;Respiratory ciliated cells: 195.7;Syncytiotrophoblasts: 229.7" "Cell type enriched" "Detected in many" 4 "fibroblast: 244.5" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 291.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 1.9;naive CD8 T-cell: 1.2" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 6 "Gastric cancer: 115.2;liver cancer: 376.5;Rhabdoid: 143.8;testis cancer: 249.1" "Adrenal gland - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblasts_1, Minor Salivary Gland - Fibroblasts, Pancreas - Fibroblasts, Spleen - Smooth muscle cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006316 Supported "Plasma membrane" NA NA 89000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 18: Liver cancer - Metabolism" "Cluster 108: Fibroblasts - ECM organization" 1 "Plasma membrane" "HPA006316: " "unprognostic (1.06e-2)" "unprognostic (1.56e-1)" "unprognostic (1.61e-1)" "unprognostic (2.35e-1)" "unprognostic (1.32e-1)" "unprognostic (3.91e-2)" "unprognostic (3.97e-1)" "unprognostic (3.56e-1)" "unprognostic (1.45e-1)" "unprognostic (1.42e-2)" "unprognostic (3.76e-2)" "unprognostic (3.55e-2)" "unprognostic (2.81e-3)" "unprognostic (6.59e-2)" "unprognostic (4.97e-3)" "unprognostic (2.25e-3)" "unprognostic (1.44e-1)" "unprognostic (3.29e-2)" "unprognostic (6.43e-3)" "unprognostic (1.86e-2)" "unprognostic (1.24e-1)" "unprognostic (3.61e-2)" "unprognostic (1.16e-1)" "unprognostic (1.17e-1)" "unprognostic (2.44e-1)" "unprognostic (1.91e-1)" "unprognostic (1.34e-1)" "potential prognostic unfavorable (1.01e-4)" "unprognostic (1.12e-1)" "unprognostic (1.84e-1)" "unprognostic (1.68e-2)" GPC4 K-glypican ENSG00000076716 "Glypican 4" O75487 X 133300103-133415489 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Deafness, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 90.3;Ependymal cells: 102.5;Gonadotrophs: 348.9;Loop of henle epithelial cells: 83.7;Pituitary stem cells: 136.7;Proximal tubule cells: 155.6;Transitional alveolar cells: 79.6" "Cell type enhanced" "Detected in many" "ependymal cell: 103.5;hippocampal dentate gyrus: 99.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "testis cancer: 223.0" "Pituitary gland - Gonadotropes, Prostate - Smooth muscle cells, Spleen - Fibroblasts_2, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030834, HPA030836" Approved Approved "Nucleoplasm,Plasma membrane" "Intracellular and membrane" "No annotated function" NA NA 63000 "Cluster 75: Ovary - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 23 "Plasma membrane" Nucleoplasm "HPA030834: , HPA030836: " "unprognostic (6.50e-2)" "unprognostic (6.62e-2)" "unprognostic (4.89e-2)" "unprognostic (1.12e-1)" "unprognostic (2.22e-1)" "unprognostic (1.44e-1)" "unprognostic (4.73e-2)" "unprognostic (2.03e-3)" "unprognostic (5.35e-3)" "unprognostic (2.82e-3)" "potential prognostic favorable (2.31e-7)" "unprognostic (1.96e-2)" "potential prognostic favorable (3.25e-4)" "unprognostic (5.97e-2)" "unprognostic (7.93e-2)" "unprognostic (1.24e-3)" "unprognostic (1.81e-1)" "unprognostic (1.15e-1)" "unprognostic (2.60e-2)" "unprognostic (1.36e-1)" "unprognostic (2.41e-1)" "unprognostic (1.72e-2)" "unprognostic (4.89e-2)" "unprognostic (7.14e-2)" "unprognostic (4.31e-2)" "unprognostic (6.24e-2)" "unprognostic (2.64e-2)" "unprognostic (1.30e-1)" "unprognostic (2.70e-1)" "unprognostic (1.15e-1)" "unprognostic (1.73e-1)" GPC5 ENSG00000179399 "Glypican 5" P78333 13 91398621-92873682 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 13.3;kidney: 6.8;testis: 5.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 1706.4;Astrocytes: 5171.2;Brain inhibitory neurons: 963.2;Corticotrophs: 1891.3;Distal convoluted tubule cells: 2588.9;Gonadotrophs: 3182.3;Granulosa cells: 1289.5;Loop of henle epithelial cells: 1355.5;Renal connecting tubule cells: 1144.3;Sertoli cells: 3976.8" "Cell type enhanced" "Detected in all" "astrocyte: 5083.9;lower rhombic lip: 5156.8;pericyte: 5675.4" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 4.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 3.1" "Adrenal gland - Adrenal medulla cells, Pituitary gland - Gonadotropes, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040152, HPA044081" Enhanced Approved Nucleoplasm,Cytosol "Intracellular and membrane" "No annotated function" NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 24: Neurons - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 28: Astrocytes - Homeostasis & neuron support" 6 Nucleoplasm Cytosol "HPA040152: , HPA044081: " "potential prognostic unfavorable (7.76e-4)" "unprognostic (1.99e-1)" "unprognostic (1.09e-1)" "unprognostic (7.33e-3)" "unprognostic (1.10e-2)" "unprognostic (2.88e-2)" "unprognostic (3.23e-2)" GPC6 ENSG00000183098 "Glypican 6" Q9Y625 13 93226807-94408020 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 1074.2;Bergmann glia: 1539.7;Corticotrophs: 1145.3;Hepatic stellate cells: 787.5;Hepatocytes: 901.2;Myosatellite cells: 988.5;Oligodendrocyte progenitor cells: 964.8;Pancreatic islet cells: 908.7;Pituicytes/FSCs: 3669.2;Pituitary stem cells: 829.7;Podocytes: 2171.1;Retinal bipolar cells: 775.9;Rod photoreceptor cells: 1570.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 39.0;testis cancer: 36.4" "Breast - Adipocytes (Breast), Colon - Fibroblasts, Minor Salivary Gland - Smooth muscle cells, Prostate - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA013601, HPA017671" Approved Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" "No annotated function" NA NA 810000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 4 "Golgi apparatus, Vesicles" "HPA013601: , HPA017671: " "unprognostic (1.35e-2)" "unprognostic (1.25e-1)" "unprognostic (1.03e-1)" "unprognostic (8.43e-2)" "unprognostic (9.76e-2)" "unprognostic (8.15e-2)" "unprognostic (1.20e-1)" "unprognostic (5.33e-3)" "unprognostic (4.19e-2)" "unprognostic (9.21e-3)" "potential prognostic favorable (2.67e-5)" "unprognostic (1.22e-2)" "unprognostic (3.35e-2)" "unprognostic (1.48e-1)" "unprognostic (3.19e-1)" "unprognostic (1.54e-3)" "unprognostic (1.95e-3)" "unprognostic (1.63e-1)" "unprognostic (3.24e-3)" "unprognostic (3.83e-2)" "unprognostic (4.27e-2)" "unprognostic (4.99e-2)" "unprognostic (4.38e-2)" "unprognostic (3.94e-2)" "unprognostic (1.21e-1)" "unprognostic (1.26e-3)" "unprognostic (9.85e-2)" "unprognostic (1.38e-3)" "unprognostic (9.20e-2)" "unprognostic (3.67e-1)" "unprognostic (2.02e-1)" GPCPD1 "GDE5, GDPD6, KIAA1434" ENSG00000125772 "Glycerophosphocholine phosphodiesterase 1" Q9NPB8 20 5544439-5611006 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 71.3" "Cell type enhanced" "Detected in many" "Monocyte progenitors: 493.6;monocytes: 1140.7;Neutrophils: 1542.2;Salivary acinar cells: 512.1" "Cell type enriched" "Detected in all" 7 "endothelial cell: 2622.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042987 Uncertain Nucleoplasm NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 15: Bone marrow - Innate immune response" "Cluster 37: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 4 Nucleoplasm "HPA042987: " "unprognostic (1.40e-1)" "unprognostic (1.36e-1)" "potential prognostic favorable (1.99e-4)" "unprognostic (1.18e-2)" "unprognostic (1.37e-1)" "unprognostic (4.52e-2)" "unprognostic (4.15e-2)" "unprognostic (6.34e-2)" "unprognostic (1.26e-1)" "unprognostic (1.57e-2)" "unprognostic (8.78e-2)" "unprognostic (9.95e-2)" "unprognostic (1.47e-3)" "unprognostic (1.60e-1)" "unprognostic (5.73e-2)" "unprognostic (7.61e-2)" "unprognostic (2.06e-2)" "unprognostic (3.45e-2)" "unprognostic (2.01e-1)" "unprognostic (1.05e-1)" "unprognostic (6.79e-2)" "unprognostic (6.71e-2)" "potential prognostic unfavorable (1.52e-5)" "unprognostic (1.30e-1)" "unprognostic (2.82e-2)" "unprognostic (1.57e-3)" "unprognostic (2.91e-2)" "unprognostic (1.33e-1)" "unprognostic (1.98e-1)" "unprognostic (1.76e-1)" "unprognostic (2.31e-3)" GPD1 ENSG00000167588 "Glycerol-3-phosphate dehydrogenase 1" P21695 12 50103982-50111313 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 572.7;breast: 247.8;skeletal muscle: 540.7" "Cell type enhanced" "Detected in many" "Adipocytes: 318.4;Enterocytes: 249.1;Hepatocytes: 134.1;Myonuclei: 60.6;Proximal tubule cells: 36.2" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 30.6;oligodendrocyte: 56.2" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 50.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 3.6;Gastric cancer: 4.4;liver cancer: 5.1" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Minor Salivary Gland - Adipocytes (Minor salivary gland), Pituitary gland - Gonadotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044620, HPA058621" Enhanced NA NA 3900000 "Cluster 25: Non-specific - Basic cellular processes" "Cluster 22: Non-specific - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 89: Adipocytes - Lipid metabolism" 5 "HPA044620: , HPA058621: " "unprognostic (1.86e-2)" "unprognostic (2.71e-2)" "unprognostic (4.39e-3)" "unprognostic (7.24e-2)" "unprognostic (8.46e-3)" "unprognostic (1.65e-2)" "unprognostic (1.56e-2)" "potential prognostic unfavorable (7.35e-4)" "unprognostic (4.14e-2)" "unprognostic (1.72e-1)" "unprognostic (7.81e-2)" "unprognostic (8.85e-3)" "unprognostic (1.04e-3)" "unprognostic (1.60e-2)" "unprognostic (4.17e-2)" "unprognostic (3.23e-2)" "unprognostic (3.64e-1)" "unprognostic (2.45e-2)" "unprognostic (4.16e-2)" "unprognostic (3.75e-2)" "unprognostic (1.89e-1)" "unprognostic (8.59e-2)" "unprognostic (2.86e-1)" "unprognostic (7.75e-2)" "unprognostic (1.39e-1)" GPD1L KIAA0089 ENSG00000152642 "Glycerol-3-phosphate dehydrogenase 1 like" Q8N335 3 32105689-32168709 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Brugada syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 148.4;tongue: 236.5" "Cell type enhanced" "Detected in many" "Myonuclei: 234.4;Thymic myoid cells: 176.8" "Cell type enhanced" "Detected in all" "endothelial cell: 121.1" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 76.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Liver - Vascular endothelial cells, Pituitary gland - Thyrotropes, Skeletal muscle - Skeletal myocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 14: Neurons - Synaptic function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 55: Myocytes - Oxidative muscle function" 5 "unprognostic (1.43e-3)" "unprognostic (7.20e-2)" "unprognostic (1.63e-1)" "unprognostic (2.80e-1)" "unprognostic (2.73e-2)" "unprognostic (1.46e-1)" "unprognostic (1.86e-2)" "unprognostic (1.55e-1)" "unprognostic (2.18e-1)" "unprognostic (3.89e-2)" "validated prognostic favorable (1.39e-8)" "validated prognostic favorable (1.08e-4)" "unprognostic (8.84e-3)" "unprognostic (1.12e-3)" "potential prognostic unfavorable (2.90e-4)" "potential prognostic favorable (4.98e-5)" "unprognostic (3.15e-1)" "unprognostic (1.22e-1)" "unprognostic (1.57e-1)" "unprognostic (1.05e-1)" "unprognostic (1.56e-2)" "unprognostic (1.27e-1)" "unprognostic (4.32e-3)" "unprognostic (6.92e-2)" "unprognostic (7.47e-3)" "unprognostic (4.45e-2)" "unprognostic (1.73e-1)" "unprognostic (9.37e-2)" "unprognostic (1.48e-1)" "unprognostic (1.10e-2)" "unprognostic (2.27e-2)" GPD2 ENSG00000115159 "Glycerol-3-phosphate dehydrogenase 2" P43304 2 156435290-156613735 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 504.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 3.3;eosinophil: 1.7;intermediate monocyte: 1.6;myeloid DC: 2.7;neutrophil: 1.1;non-classical monocyte: 2.3" "Group enriched" "Detected in many" 5 "dendritic cells: 2.7;granulocytes: 1.7;monocytes: 3.3" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008012, HPA045506" Enhanced Supported Mitochondria NA NA 240000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 29: Forebrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 4 Mitochondria "HPA008012: , HPA045506: " "unprognostic (2.11e-1)" "unprognostic (5.10e-2)" "unprognostic (3.20e-1)" "unprognostic (3.48e-1)" "unprognostic (2.15e-1)" "unprognostic (2.72e-3)" "unprognostic (2.64e-1)" "unprognostic (4.64e-2)" "unprognostic (5.57e-2)" "unprognostic (7.81e-3)" "potential prognostic favorable (3.02e-6)" "unprognostic (3.44e-3)" "unprognostic (3.01e-1)" "potential prognostic unfavorable (2.94e-4)" "unprognostic (1.13e-3)" "potential prognostic unfavorable (8.05e-4)" "unprognostic (7.67e-3)" "unprognostic (3.19e-3)" "unprognostic (1.47e-1)" "unprognostic (6.75e-2)" "unprognostic (3.58e-1)" "unprognostic (3.14e-3)" "unprognostic (4.79e-1)" "unprognostic (1.04e-1)" "unprognostic (9.33e-2)" "unprognostic (7.87e-2)" "unprognostic (2.53e-1)" "unprognostic (3.09e-1)" "unprognostic (2.35e-1)" "unprognostic (3.70e-2)" "unprognostic (3.68e-2)" GPER1 "CEPR, CMKRL2, DRY12, FEG-1, GPCR-Br, GPER, GPR30, LERGU, LERGU2, LyGPR" ENSG00000164850 "G protein-coupled estrogen receptor 1" Q99527 7 1082208-1093815 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Apoptosis, Cell cycle, Differentiation, Immunity, Inflammatory response, Innate immunity, Neurogenesis" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 40.9" "Cell type enhanced" "Detected in many" "Epicardial cells: 22.7;Gastric chief cells: 32.8;Hepatocytes: 27.7;Kupffer cells: 24.6;Pericytes: 19.6;Renal collecting duct principal cells: 15.9;Respiratory ionocytes: 35.6;Tuft cells: 34.6" "Cell type enriched" "Detected in many" 7 "pericyte: 311.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.9;intermediate monocyte: 2.7;myeloid DC: 5.8" "Group enriched" "Detected in many" 23 "dendritic cells: 5.8;monocytes: 2.9" "Cancer enhanced" "Detected in many" "lymphoma: 11.1" "Liver - Hepatocytes, Stomach - Chief cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016718, HPA027052" Approved Supported Nucleoplasm,Nucleoli,Vesicles,Cytosol NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 22: Non-specific - Basic cellular functions" Nucleoli "Nucleoplasm, Vesicles, Cytosol" "HPA016718: , HPA027052: " "unprognostic (2.10e-1)" "unprognostic (7.70e-2)" "unprognostic (1.18e-1)" "unprognostic (1.35e-1)" "unprognostic (1.13e-3)" "unprognostic (1.39e-1)" "unprognostic (9.26e-2)" "unprognostic (9.17e-2)" "unprognostic (9.59e-2)" "validated prognostic favorable (3.87e-5)" "validated prognostic favorable (3.44e-4)" "unprognostic (1.97e-2)" "unprognostic (1.70e-1)" "unprognostic (4.94e-2)" "unprognostic (2.72e-1)" "unprognostic (7.31e-2)" "unprognostic (2.86e-2)" "unprognostic (3.65e-1)" "unprognostic (2.59e-1)" "unprognostic (1.97e-1)" "potential prognostic favorable (9.64e-4)" "unprognostic (1.28e-1)" "unprognostic (4.86e-2)" "unprognostic (7.22e-2)" "unprognostic (4.50e-2)" "unprognostic (1.44e-2)" GPHA2 "A2, GPA2, MGC126572, ZSIG51" ENSG00000149735 "Glycoprotein hormone subunit alpha 2" Q96T91 11 64934471-64935893 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "pancreas: 339.8" "Cell type enhanced" "Detected in some" "Early primary spermatocytes: 10.2;Ocular epithelial cells: 88.2;Oocytes: 18.4;Pancreatic acinar cells: 40.0;Pituitary stem cells: 12.2" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 8 "Testicular Germ Cell Tumor (TCGA): 31.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 1.5;liver cancer: 1.3;Rhabdoid: 1.1" "Pancreas - Exocrine glandular cells, Stomach - Chief cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA067068 Approved Vesicles "Secreted to blood" Hormone NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 15: Non-specific - Transcription" "Cluster 18: Liver cancer - Metabolism" "Cluster 100: Stratified epithelial cells - Barrier functions" 1 Vesicles "HPA067068: " "unprognostic (5.68e-3)" "unprognostic (3.48e-1)" "unprognostic (4.33e-2)" "unprognostic (1.91e-3)" GPHB5 "GPB5, ZLUT1" ENSG00000179600 "Glycoprotein hormone subunit beta 5" Q86YW7 14 63312835-63318935 "Predicted secreted proteins" Hormone "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Foveolar cells: 1.0;Gastric progenitor cells: 1.3;Respiratory ionocytes: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" Hormone NA NA "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 109: Neurons - Neuronal signaling" 7 GPHN KIAA1385 ENSG00000171723 Gephyrin Q9NQX3 14 66507407-67181803 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Molybdenum cofactor biosynthesis" "Multifunctional enzyme, Transferase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 61.5;liver: 58.3" "Cell type enhanced" "Detected in many" "Podocytes: 1784.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003116, CAB004419, HPA024694" Enhanced Approved Vesicles,Cytosol NA NA 3600 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 36: Brain & Liver - Signaling" "Cluster 16: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 18 Vesicles Cytosol "CAB004419: , HPA003116: , HPA024694: " "unprognostic (1.75e-1)" "unprognostic (1.45e-2)" "unprognostic (2.66e-2)" "unprognostic (3.30e-3)" "unprognostic (1.66e-1)" "unprognostic (3.53e-2)" "unprognostic (1.19e-1)" "unprognostic (1.14e-2)" "unprognostic (1.83e-2)" "unprognostic (1.31e-1)" "unprognostic (2.46e-2)" "unprognostic (2.24e-3)" "potential prognostic favorable (7.31e-5)" "unprognostic (1.62e-2)" "unprognostic (2.72e-2)" "unprognostic (2.79e-1)" "unprognostic (2.82e-1)" "unprognostic (8.09e-2)" "unprognostic (5.12e-1)" "unprognostic (4.02e-1)" "unprognostic (8.50e-2)" "unprognostic (1.37e-2)" "unprognostic (9.39e-2)" "unprognostic (3.10e-1)" "unprognostic (6.64e-2)" "unprognostic (2.21e-3)" "unprognostic (7.80e-2)" "unprognostic (8.30e-3)" "unprognostic (6.90e-2)" "unprognostic (3.02e-1)" "unprognostic (4.63e-2)" GPI "AMF, NLK" ENSG00000105220 "Glucose-6-phosphate isomerase" P06744 19 34359480-34402413 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Gluconeogenesis, Glycolysis" "Cytokine, Growth factor, Isomerase" "Cancer-related genes, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Late spermatids: 1200.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018655, HPA024305, CAB040563, HPA052171, CAB080077, CAB080078, CAB080085" Enhanced Approved "Plasma membrane,Cytosol" "Secreted to blood" Cytokine NA No 58000000 "Cluster 25: Non-specific - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 4: Non-specific - Transcription" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 16 Cytosol "Plasma membrane" "CAB018655: , CAB040563: , CAB080077: , CAB080078: , CAB080085: , HPA024305: , HPA052171: " "unprognostic (3.07e-1)" "unprognostic (2.59e-2)" "unprognostic (3.32e-2)" "unprognostic (7.31e-3)" "unprognostic (1.15e-2)" "unprognostic (3.22e-1)" "unprognostic (3.62e-2)" "unprognostic (8.59e-3)" "unprognostic (7.58e-3)" "unprognostic (7.92e-3)" "potential prognostic favorable (3.38e-7)" "unprognostic (5.90e-2)" "unprognostic (8.25e-2)" "unprognostic (4.38e-2)" "unprognostic (4.21e-3)" "validated prognostic unfavorable (8.08e-5)" "validated prognostic unfavorable (7.84e-4)" "unprognostic (7.33e-2)" "unprognostic (1.99e-1)" "unprognostic (8.15e-2)" "unprognostic (1.66e-1)" "unprognostic (2.53e-1)" "unprognostic (2.17e-1)" "potential prognostic unfavorable (7.65e-4)" "unprognostic (1.36e-1)" "unprognostic (7.90e-2)" "unprognostic (1.29e-1)" "unprognostic (2.03e-1)" "unprognostic (3.85e-2)" "potential prognostic unfavorable (7.38e-4)" "unprognostic (3.87e-2)" GPIHBP1 "GPI-HBP1, LOC338328" ENSG00000277494 "Glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1" Q8IV16 8 143213218-143217170 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 85.2;brain: 70.0;breast: 53.2" "Group enriched" "Detected in some" 12 "Lymphatic endothelial cells: 28.5;Oligodendrocytes: 23.3;Vascular endothelial cells: 71.9" "Group enriched" "Detected in some" 7 "endothelial cell: 32.9;oligodendrocyte: 34.6" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 8.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA066302 Enhanced Approved "Principal piece,End piece" "Intracellular and membrane" Transport NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 7: Liver cancer - Metabolism" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 30 "End piece" "Principal piece" "HPA066302: " "unprognostic (1.48e-1)" "unprognostic (1.40e-1)" "unprognostic (1.98e-2)" "unprognostic (3.48e-1)" "unprognostic (1.17e-1)" "validated prognostic favorable (2.82e-7)" "validated prognostic favorable (6.70e-4)" "unprognostic (1.49e-1)" "unprognostic (2.05e-3)" "unprognostic (2.05e-2)" "unprognostic (1.13e-2)" "unprognostic (1.58e-1)" "unprognostic (2.17e-3)" "unprognostic (1.60e-1)" "unprognostic (1.10e-1)" "unprognostic (9.80e-2)" "unprognostic (1.39e-1)" "unprognostic (4.19e-2)" GPKOW "GPATC5, GPATCH5, Mos2, Spp2, T54" ENSG00000068394 "G-patch domain and KOW motifs" Q92917 X 49113407-49123735 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 59.9;Syncytiotrophoblasts: 54.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000287, HPA001894" Enhanced Enhanced Nucleoplasm NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 69 Nucleoplasm "HPA000287: , HPA001894: " "unprognostic (2.81e-1)" "unprognostic (9.72e-3)" "unprognostic (6.09e-2)" "unprognostic (7.24e-2)" "unprognostic (1.84e-1)" "unprognostic (3.82e-1)" "unprognostic (2.19e-1)" "potential prognostic favorable (2.73e-6)" "unprognostic (1.16e-1)" "unprognostic (9.98e-3)" "potential prognostic favorable (2.45e-4)" "unprognostic (4.35e-2)" "unprognostic (3.06e-1)" "validated prognostic unfavorable (7.62e-4)" "validated prognostic unfavorable (1.95e-4)" "unprognostic (2.54e-2)" "unprognostic (7.36e-2)" "unprognostic (4.82e-2)" "unprognostic (2.33e-1)" "unprognostic (1.95e-1)" "unprognostic (1.20e-1)" "unprognostic (1.48e-1)" "unprognostic (3.38e-1)" "unprognostic (2.47e-1)" "unprognostic (7.86e-2)" "unprognostic (1.05e-1)" "unprognostic (2.60e-1)" "unprognostic (9.48e-2)" "unprognostic (1.81e-1)" "unprognostic (3.50e-1)" "unprognostic (1.02e-1)" GPLD1 ENSG00000112293 "Glycosylphosphatidylinositol specific phospholipase D1" P80108 6 24424565-24495205 "Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 43.1" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 63.8;Brain excitatory neurons: 71.1;Brain inhibitory neurons: 70.6;Cardiomyocytes: 82.9;Cone photoreceptor cells: 105.6;Hepatocytes: 213.5;Myonuclei: 62.8;Other brain neurons: 68.7" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in some" 7 "Liver Hepatocellular Carcinoma (TCGA): 13.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "lymphoma: 6.3" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Liver - Hepatocytes, Prostate - Smooth muscle cells, Skin - Keratinocyte (granular), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008625, HPA012500" Uncertain "Secreted to blood" Enzyme NA NA 103000000000 3300000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 2: Neurons - Nucleosome" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 2 "CAB008625: , HPA012500: " "unprognostic (2.48e-2)" "unprognostic (1.76e-2)" "unprognostic (1.16e-1)" "unprognostic (8.85e-2)" "unprognostic (2.60e-1)" "validated prognostic favorable (6.73e-5)" "validated prognostic favorable (6.67e-8)" "unprognostic (2.82e-2)" "unprognostic (3.30e-2)" "unprognostic (1.96e-2)" "unprognostic (1.11e-1)" "unprognostic (1.30e-2)" "unprognostic (3.01e-1)" "unprognostic (8.73e-2)" GPM6A GPM6 ENSG00000150625 "Glycoprotein M6A" P51674 4 175632934-176002664 "Predicted intracellular proteins, Predicted membrane proteins" Neurogenesis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 614.0" "Cell type enhanced" "Detected in many" "Astrocytes: 5162.2;Bergmann glia: 5062.5;Brain excitatory neurons: 1071.4;Brain inhibitory neurons: 848.7;Choroid plexus epithelial cells: 2309.3;Ependymal cells: 1075.7;Müller glia: 1698.5;Oligodendrocyte progenitor cells: 1865.8;Retinal pigment epithelial cells: 2110.2" "Cell type enhanced" "Detected in all" "Bergmann glia: 5366.0" "Cancer enriched" "Detected in many" 26 "Glioblastoma Multiforme (TCGA): 455.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "memory B-cell: 34.9;naive B-cell: 16.7" "Lineage enriched" "Detected in many" 12 "B-cells: 34.9" "Cancer enhanced" "Detected in many" "Brain cancer: 16.2;lymphoma: 10.7" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Adrenal gland - Endothelial cells, Liver - Hepatic stellate cells, Lung - Alveolar cells type 1, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017338 Supported NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 72: Neuronal - Signal transduction" "Cluster 28: Astrocytes - Homeostasis & neuron support" 14 "HPA017338: " "unprognostic (1.60e-2)" "unprognostic (2.74e-2)" "unprognostic (4.08e-1)" "unprognostic (2.79e-3)" "unprognostic (1.49e-2)" "unprognostic (2.17e-1)" "unprognostic (8.60e-2)" "unprognostic (1.29e-1)" "unprognostic (1.60e-2)" "unprognostic (1.21e-2)" "unprognostic (5.12e-2)" "unprognostic (1.38e-1)" "potential prognostic favorable (7.54e-6)" "unprognostic (2.57e-1)" "unprognostic (9.68e-3)" "unprognostic (5.63e-2)" "unprognostic (2.03e-1)" "unprognostic (4.47e-3)" "unprognostic (1.82e-2)" "unprognostic (2.72e-1)" "unprognostic (5.51e-3)" "unprognostic (1.69e-1)" "unprognostic (9.70e-2)" "unprognostic (2.25e-2)" "unprognostic (7.36e-2)" "unprognostic (1.78e-1)" "unprognostic (2.34e-3)" "unprognostic (2.31e-2)" GPM6B "M6B, MGC17150, MGC54284" ENSG00000046653 "Glycoprotein M6B" Q13491 X 13770939-13938638 "Predicted membrane proteins" "Differentiation, Neurogenesis, Osteogenesis, Protein transport, Transport" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 14 "brain: 709.5;retina: 180.8" "Cell type enhanced" "Detected in many" "Astrocytes: 1043.0;Bergmann glia: 1587.6;Ependymal cells: 522.3;Melanocytes: 877.3;Müller glia: 1895.6;Oligodendrocyte progenitor cells: 642.3;Oligodendrocytes: 1811.1;Pituicytes/FSCs: 714.2;Rod photoreceptor cells: 434.2;Schwann cells: 1458.9" "Cell type enhanced" "Detected in all" "Bergmann glia: 1815.6;oligodendrocyte: 2340.1" "Cancer enriched" "Detected in many" 5 "Glioblastoma Multiforme (TCGA): 497.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 230 "plasmacytoid DC: 78.2" "Lineage enriched" "Detected in single" 313 "dendritic cells: 78.2" "Group enriched" "Detected in many" 5 "Brain cancer: 36.3;Rhabdoid: 47.5;skin cancer: 77.9;testis cancer: 34.9" "Breast - Breast glandular cells, Colon - Enteric glia cells, Prostate - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002913 Approved NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 72: Neuronal - Signal transduction" "Cluster 11: Muller glia cells - Retinal homeostasis" 2 "HPA002913: " "unprognostic (6.09e-2)" "unprognostic (6.44e-2)" "unprognostic (9.43e-2)" "unprognostic (2.08e-1)" "unprognostic (1.23e-1)" "unprognostic (1.30e-1)" "unprognostic (2.15e-2)" "unprognostic (8.88e-2)" "unprognostic (7.90e-3)" "unprognostic (2.86e-1)" "unprognostic (3.74e-2)" "unprognostic (1.37e-1)" "unprognostic (8.10e-2)" "potential prognostic favorable (9.59e-4)" "unprognostic (1.36e-2)" "unprognostic (1.53e-1)" "unprognostic (8.12e-3)" "unprognostic (7.21e-2)" "unprognostic (1.69e-1)" "unprognostic (2.95e-2)" "unprognostic (4.24e-1)" "unprognostic (2.54e-2)" "unprognostic (7.57e-2)" "potential prognostic favorable (1.18e-4)" "unprognostic (4.06e-3)" "unprognostic (5.65e-2)" "unprognostic (2.50e-1)" "unprognostic (4.11e-3)" "unprognostic (2.77e-1)" GPN1 "ATPBD1A, MBDIN, NTPBP, RPAP4, XAB1" ENSG00000198522 "GPN-loop GTPase 1" Q9HCN4 2 27628247-27651511 "Essential proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 85.7;Late primary spermatocytes: 95.3;Late spermatids: 114.3;Oocytes: 73.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036793, HPA036794, CAB037303" Uncertain Supported Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 79 "Nucleoplasm, Cytosol" Mitochondria "CAB037303: , HPA036793: , HPA036794: " "unprognostic (4.09e-2)" "unprognostic (5.16e-2)" "unprognostic (4.94e-2)" "unprognostic (5.96e-3)" "unprognostic (2.35e-1)" "unprognostic (3.50e-1)" "unprognostic (2.31e-1)" "unprognostic (8.97e-2)" "unprognostic (4.37e-2)" "unprognostic (1.43e-3)" "potential prognostic favorable (6.51e-5)" "unprognostic (5.15e-2)" "unprognostic (3.67e-2)" "validated prognostic unfavorable (8.55e-7)" "validated prognostic unfavorable (9.90e-4)" "unprognostic (1.18e-3)" "potential prognostic unfavorable (6.20e-4)" "unprognostic (3.18e-2)" "unprognostic (1.92e-1)" "unprognostic (1.05e-1)" "unprognostic (1.76e-1)" "unprognostic (1.93e-3)" "unprognostic (1.21e-3)" "unprognostic (4.97e-2)" "unprognostic (2.33e-2)" "unprognostic (2.05e-1)" "unprognostic (6.56e-3)" "unprognostic (4.30e-1)" "unprognostic (2.19e-1)" "unprognostic (1.94e-1)" "unprognostic (4.07e-2)" GPN2 "ATPBD1B, FLJ10349" ENSG00000142751 "GPN-loop GTPase 2" Q9H9Y4 1 26876132-26890283 "Essential proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028059 Uncertain NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 22 "HPA028059: " "unprognostic (8.70e-2)" "unprognostic (8.58e-2)" "unprognostic (3.79e-3)" "unprognostic (8.72e-2)" "unprognostic (6.28e-3)" "unprognostic (1.22e-1)" "unprognostic (6.69e-3)" "unprognostic (3.57e-3)" "unprognostic (4.36e-3)" "potential prognostic unfavorable (6.21e-4)" "potential prognostic favorable (6.55e-4)" "unprognostic (4.42e-2)" "unprognostic (1.86e-1)" "potential prognostic unfavorable (2.42e-6)" "unprognostic (6.63e-3)" "unprognostic (1.63e-1)" "unprognostic (7.29e-2)" "unprognostic (1.72e-1)" "unprognostic (7.83e-2)" "unprognostic (7.98e-3)" "unprognostic (2.52e-2)" "unprognostic (5.32e-2)" "unprognostic (2.11e-2)" "unprognostic (2.37e-1)" "unprognostic (1.91e-1)" "unprognostic (7.41e-3)" "unprognostic (1.25e-1)" "unprognostic (1.98e-1)" "unprognostic (3.06e-1)" "unprognostic (8.70e-3)" "unprognostic (6.35e-3)" GPN3 "ATPBD1C, MGC14560" ENSG00000111231 "GPN-loop GTPase 3" Q9UHW5 12 110452486-110469268 "Essential proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 139.9;Hofbauer cells: 140.8;Late primary spermatocytes: 235.8" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 56.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039764, HPA047793" Uncertain Approved "Nuclear speckles,Cytosol" Yes No "Cluster 29: Non-specific - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 49 "Nuclear speckles" Cytosol "HPA039764: , HPA047793: " "unprognostic (2.28e-2)" "potential prognostic unfavorable (5.55e-4)" "unprognostic (1.98e-2)" "unprognostic (1.39e-2)" "unprognostic (1.02e-1)" "unprognostic (1.18e-1)" "unprognostic (1.03e-1)" "unprognostic (2.53e-1)" "unprognostic (4.69e-3)" "unprognostic (6.81e-2)" "potential prognostic favorable (5.15e-8)" "unprognostic (3.54e-3)" "unprognostic (5.73e-2)" "validated prognostic unfavorable (6.10e-5)" "validated prognostic unfavorable (5.35e-6)" "unprognostic (2.11e-2)" "unprognostic (2.97e-2)" "unprognostic (5.88e-2)" "unprognostic (6.44e-2)" "unprognostic (2.22e-1)" "unprognostic (1.10e-3)" "unprognostic (9.31e-2)" "potential prognostic unfavorable (6.15e-4)" "unprognostic (5.64e-2)" "unprognostic (2.73e-2)" "unprognostic (2.23e-2)" "unprognostic (7.12e-2)" "unprognostic (4.83e-2)" "unprognostic (4.19e-1)" "unprognostic (3.13e-1)" "unprognostic (2.75e-2)" GPNMB "HGFIN, NMB" ENSG00000136235 "Glycoprotein nmb" Q14956 7 23235967-23275108 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 548.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 316.4;Esophageal basal cells: 159.6;Fibroblasts: 287.0;Hofbauer cells: 547.5;Kupffer cells: 374.1;Macrophages: 360.8;Melanocytes: 1123.6;Ocular epithelial cells: 264.3;Retinal pigment epithelial cells: 183.3;Suprabasal keratinocytes: 266.5" "Group enriched" "Detected in many" 14 "central nervous system macrophage: 43.7;choroid plexus epithelial cell: 40.6;committed oligodendrocyte precursor: 40.6;fibroblast: 76.6;oligodendrocyte precursor cell: 34.8;vascular associated smooth muscle cell: 26.3" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 1218.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.1;intermediate monocyte: 3.9" "Lineage enriched" "Detected in single" 6 "monocytes: 3.9" "Cancer enriched" "Detected in many" 6 "skin cancer: 692.4" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Colon - Fibroblasts, Heart muscle - Cardiomyocytes, Lung - Macrophages, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Region enhanced" "Detected in many" "olfactory bulb: 9.7" "Low region specificity" "Detected in all" "Intracellular and membrane" "No annotated function" NA NA 22000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 58: Skin - Keratinization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 1 "unprognostic (1.54e-1)" "unprognostic (1.07e-1)" "unprognostic (1.61e-1)" "unprognostic (2.98e-2)" "unprognostic (7.66e-2)" "unprognostic (1.37e-2)" "unprognostic (1.42e-2)" "unprognostic (1.92e-3)" "unprognostic (3.88e-1)" "unprognostic (7.11e-2)" "unprognostic (2.10e-2)" "unprognostic (2.77e-1)" "unprognostic (1.10e-1)" "unprognostic (1.63e-2)" "unprognostic (1.24e-1)" "unprognostic (4.17e-2)" "unprognostic (5.48e-3)" "unprognostic (3.43e-1)" "unprognostic (1.30e-1)" "unprognostic (1.24e-1)" "unprognostic (6.88e-2)" "unprognostic (9.55e-2)" "unprognostic (8.47e-2)" "unprognostic (7.11e-2)" "unprognostic (1.51e-2)" "unprognostic (7.03e-2)" "unprognostic (9.00e-2)" "unprognostic (3.81e-3)" "unprognostic (8.88e-2)" "unprognostic (4.98e-1)" "unprognostic (2.47e-2)" GPR101 ENSG00000165370 "G protein-coupled receptor 101" Q96P66 X 137023929-137033995 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 116 "brain: 11.5" "Group enriched" "Detected in some" 7 "Brain inhibitory neurons: 8.0;Other brain neurons: 14.9" "Group enriched" "Detected in some" 9 "eccentric medium spiny neuron: 10.1;medium spiny neuron: 21.4;splatter: 6.2;thalamic excitatory: 5.7" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "basal ganglia: 26.4;hypothalamus: 30.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in many" "hypothalamus: 38.3" "Low region specificity" "Detected in many" HPA001084 Uncertain NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 47: Leukemia - Hemostasis" "Cluster 35: Neurons - Synaptic function & neurogenesis" 16 "HPA001084: " GPR107 "FLJ20998, KIAA1624, LUSTR1, RP11-88G17" ENSG00000148358 "G protein-coupled receptor 107" Q5VW38 9 130053426-130140169 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031704 Supported Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 45: Non-specific - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 24: Neutrophils - Innate immunity signal integration" 9 "Golgi apparatus" Nucleoplasm "HPA031704: " "unprognostic (1.58e-1)" "potential prognostic unfavorable (2.04e-4)" "unprognostic (1.01e-1)" "unprognostic (2.83e-3)" "unprognostic (1.40e-1)" "potential prognostic unfavorable (9.44e-4)" "unprognostic (3.00e-1)" "unprognostic (2.57e-2)" "unprognostic (3.57e-1)" "unprognostic (1.14e-1)" "potential prognostic favorable (5.98e-7)" "unprognostic (4.43e-2)" "unprognostic (4.39e-1)" "unprognostic (2.78e-3)" "unprognostic (6.84e-3)" "unprognostic (2.38e-2)" "unprognostic (1.76e-1)" "unprognostic (2.71e-2)" "unprognostic (5.43e-2)" "unprognostic (1.17e-2)" "unprognostic (4.13e-2)" "unprognostic (1.31e-1)" "unprognostic (1.63e-1)" "unprognostic (1.61e-1)" "unprognostic (5.40e-2)" "unprognostic (3.83e-1)" "unprognostic (3.14e-2)" "unprognostic (1.13e-1)" "unprognostic (2.66e-1)" "unprognostic (3.37e-2)" "unprognostic (1.02e-1)" GPR108 LUSTR2 ENSG00000125734 "G protein-coupled receptor 108" Q9NPR9 19 6729914-6737580 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 102.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041924, HPA041951, HPA063863" Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 60: Stomach - Digestion" "Cluster 47: Endothelial cells - Vasculature" "Cluster 23: Non-specific - Transcription" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 8 "Golgi apparatus" Vesicles "HPA041924: , HPA041951: , HPA063863: " "unprognostic (1.40e-1)" "potential prognostic unfavorable (3.92e-4)" "unprognostic (3.56e-1)" "unprognostic (7.39e-2)" "unprognostic (1.79e-2)" "unprognostic (1.33e-1)" "unprognostic (3.20e-1)" "unprognostic (6.02e-3)" "unprognostic (2.88e-2)" "unprognostic (1.24e-1)" "potential prognostic favorable (1.26e-11)" "unprognostic (9.90e-3)" "unprognostic (1.06e-1)" "unprognostic (4.32e-2)" "unprognostic (2.24e-2)" "unprognostic (8.49e-2)" "unprognostic (7.65e-2)" "unprognostic (1.70e-1)" "unprognostic (3.50e-1)" "unprognostic (1.70e-1)" "unprognostic (6.73e-2)" "unprognostic (1.65e-1)" "unprognostic (2.09e-1)" "unprognostic (8.03e-2)" "unprognostic (1.14e-1)" "unprognostic (2.60e-1)" "unprognostic (4.06e-2)" "unprognostic (2.18e-1)" "unprognostic (1.09e-2)" "unprognostic (1.16e-2)" "unprognostic (1.20e-1)" GPR119 "GPCR2, hGPCR2" ENSG00000147262 "G protein-coupled receptor 119" Q8TDV5 X 130379449-130385674 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 4 "pancreas: 1.9" "Group enriched" "Detected in some" 19 "Neuroendocrine cells: 11.8;Pancreatic islet cells: 31.6" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "Pancreatic Adenocarcinoma (TCGA): 2.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "thyroid cancer: 1.8" "Pancreas - Alpha cells, Stomach - Gastric enteroendocrine cells, Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 6: Non-specific - Immune response" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 1 "unprognostic (1.67e-3)" GPR12 "GPCR21, PPP1R84" ENSG00000132975 "G protein-coupled receptor 12" P47775 13 26755200-26760786 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 11.6;retina: 7.8;skin 1: 5.1" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 13.6;Brain inhibitory neurons: 23.8;Fallopian secretory cells: 6.8;Hofbauer cells: 41.3;Retinal ganglion cells: 15.5;Retinal horizontal cells: 18.0;Salivary acinar cells: 9.9;Salivary basal cells: 8.8;Salivary duct cells: 20.6;Salivary ionocytes: 18.1;Submucosal glandular cells: 7.8" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in some" 5 "Breast Invasive Carcinoma (TCGA): 1.0;Glioblastoma Multiforme (TCGA): 1.6;Ovary Serous Cystadenocarcinoma (TCGA): 1.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 1.2;Rhabdoid: 2.4" "Breast - Breast glandular cells (progenitors), Pituitary gland - Thyrotropes, Skin - Eccrine sweat gland cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050972 Uncertain NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 33: Neurons - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" "HPA050972: " "unprognostic (1.50e-3)" "unprognostic (9.57e-3)" "unprognostic (3.47e-3)" "unprognostic (3.01e-3)" GPR132 G2A ENSG00000183484 "G protein-coupled receptor 132" Q9UNW8 14 105049395-105065445 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Stress response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 7.5;lymphoid tissue: 7.2" "Cell type enhanced" "Detected in many" "B-cells: 77.1;cDC: 185.7;Endometrial glandular cells: 61.1;Endometrial secretory cells: 85.9;Innate lymphoid cells: 76.3;Macrophages: 117.8;monocytes: 252.6;Neutrophil progenitors: 64.5;Neutrophils: 346.3;T-cells: 110.2;Thymocytes: 59.3" "Group enriched" "Detected in many" 6 "central nervous system macrophage: 28.6;leukocyte: 32.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "lymphoma: 13.7;Myeloma: 7.9" "Adipose visceral - Macrophages, Adrenal gland - Macrophages, Prostate - T-cells, Skeletal muscle - Macrophages" "HPA029694, HPA029695" Supported NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" "HPA029694: , HPA029695: " "unprognostic (5.57e-2)" "unprognostic (2.99e-2)" "potential prognostic favorable (2.73e-4)" "unprognostic (2.55e-1)" "unprognostic (2.33e-2)" "unprognostic (2.62e-2)" "unprognostic (4.76e-2)" "unprognostic (3.53e-1)" "potential prognostic favorable (6.41e-4)" "unprognostic (8.95e-3)" "unprognostic (1.10e-1)" "unprognostic (8.90e-2)" "unprognostic (1.62e-1)" "unprognostic (5.22e-2)" "unprognostic (2.13e-2)" "unprognostic (3.16e-3)" "unprognostic (2.74e-1)" "unprognostic (1.76e-1)" "unprognostic (1.32e-1)" "unprognostic (2.96e-2)" "unprognostic (2.27e-2)" "unprognostic (3.78e-1)" "unprognostic (9.81e-3)" "unprognostic (1.24e-2)" "unprognostic (6.40e-2)" "unprognostic (1.82e-2)" "potential prognostic unfavorable (6.92e-5)" "unprognostic (3.48e-2)" GPR135 "HUMNPIIY20, PAFR" ENSG00000181619 "G protein-coupled receptor 135" Q8IZ08 14 59429022-59465380 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 59.3;Choroid plexus epithelial cells: 54.5;Ependymal cells: 79.4;Lactotrophs: 46.6;Proximal tubule cells: 85.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA045337 Uncertain NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 72: Neuronal - Signal transduction" "Cluster 2: Cerebellar granular cells - Neuronal signaling" "HPA045337: " "unprognostic (4.12e-1)" "unprognostic (4.96e-1)" "unprognostic (8.30e-2)" "unprognostic (3.32e-1)" "unprognostic (3.25e-1)" "unprognostic (3.03e-2)" "unprognostic (1.02e-1)" "unprognostic (1.86e-2)" GPR137 "C11orf4, GPR137A, TM7SF1L1" ENSG00000173264 "G protein-coupled receptor 137" Q96N19 11 64270062-64289500 "Predicted intracellular proteins, Predicted membrane proteins" Autophagy "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 188.9" "Cell type enhanced" "Detected in many" "Early spermatids: 175.9;Late primary spermatocytes: 315.7;Late spermatids: 1055.4;Syncytiotrophoblasts: 156.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062871 Uncertain Approved "Nucleoplasm,Nucleoli,Actin filaments" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 79: Testis - Spermatogenesis" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 3 "Nucleoplasm, Nucleoli" "Actin filaments" "HPA062871: " "unprognostic (5.14e-2)" "unprognostic (1.85e-1)" "unprognostic (5.61e-3)" "unprognostic (4.84e-2)" "unprognostic (4.55e-2)" "unprognostic (2.33e-1)" "unprognostic (1.28e-2)" "unprognostic (2.86e-2)" "unprognostic (7.10e-2)" "unprognostic (5.83e-2)" "potential prognostic unfavorable (4.25e-6)" "unprognostic (5.15e-2)" "unprognostic (6.37e-2)" "potential prognostic unfavorable (6.29e-4)" "unprognostic (1.06e-1)" "unprognostic (1.63e-2)" "unprognostic (3.71e-1)" "unprognostic (1.31e-1)" "unprognostic (2.18e-1)" "unprognostic (3.22e-2)" "unprognostic (6.99e-3)" "unprognostic (3.30e-2)" "unprognostic (1.53e-1)" "unprognostic (1.48e-1)" "unprognostic (4.66e-1)" "unprognostic (1.26e-1)" "unprognostic (2.27e-1)" "unprognostic (6.55e-2)" "unprognostic (1.98e-1)" "unprognostic (2.65e-1)" "unprognostic (2.85e-1)" GPR137B TM7SF1 ENSG00000077585 "G protein-coupled receptor 137B" O60478 1 236142505-236221865 "Predicted membrane proteins, Transporters" Autophagy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 125.6" "Cell type enhanced" "Detected in many" "cDC: 264.1;Epididymal efferent duct absorptive cells: 184.4;Hofbauer cells: 236.6;Kupffer cells: 265.5;Macrophages: 230.6;Melanocytes: 317.9;Müller glia: 314.9;Rod photoreceptor cells: 394.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 17.6" "Group enriched" "Detected in many" 5 "granulocytes: 17.6;monocytes: 7.3" "Cancer enhanced" "Detected in all" "skin cancer: 69.0" "Adipose subcutaneous - Macrophages, Minor Salivary Gland - Macrophages, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026422 Approved NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 82: Dendritic cells - Antigen presentation" 1 "HPA026422: " "unprognostic (6.60e-2)" "unprognostic (1.27e-3)" "unprognostic (3.65e-1)" "unprognostic (2.63e-1)" "unprognostic (4.38e-2)" "unprognostic (9.06e-2)" "unprognostic (1.75e-1)" "unprognostic (2.55e-1)" "unprognostic (3.11e-1)" "unprognostic (2.31e-2)" "potential prognostic favorable (3.72e-6)" "unprognostic (3.92e-2)" "unprognostic (1.06e-1)" "unprognostic (5.25e-2)" "unprognostic (2.06e-1)" "unprognostic (1.26e-1)" "unprognostic (1.36e-1)" "unprognostic (1.82e-1)" "unprognostic (1.26e-1)" "unprognostic (1.72e-1)" "unprognostic (7.94e-2)" "unprognostic (1.86e-1)" "unprognostic (4.78e-2)" "unprognostic (5.72e-2)" "unprognostic (1.66e-2)" "unprognostic (8.09e-2)" "unprognostic (4.26e-2)" "unprognostic (2.16e-1)" "unprognostic (1.03e-1)" "unprognostic (2.70e-1)" "unprognostic (1.77e-1)" GPR137C "DKFZp762F0713, TM7SF1L2" ENSG00000180998 "G protein-coupled receptor 137C" Q8N3F9 14 52552836-52637713 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 26.0;epididymis: 7.3;retina: 15.4" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 202.1;Brain excitatory neurons: 153.7;Brain inhibitory neurons: 148.0;Oligodendrocyte progenitor cells: 140.3;Oligodendrocytes: 138.4;Retinal bipolar cells: 212.6;Rod photoreceptor cells: 238.0;Sertoli cells: 99.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 15 "NK-cells: 1.5;T-cells: 1.4" "Low cancer specificity" "Detected in many" "Skin - Outer root sheath cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003640, HPA030763" Uncertain Approved Vesicles NA NA "Cluster 1: T-cells - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 16: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" Vesicles "HPA003640: , HPA030763: " "unprognostic (3.54e-2)" "unprognostic (1.34e-2)" "unprognostic (8.25e-2)" "unprognostic (3.09e-2)" "unprognostic (2.35e-2)" "potential prognostic favorable (1.11e-4)" "unprognostic (5.09e-2)" "unprognostic (2.21e-1)" "unprognostic (2.12e-1)" "unprognostic (4.80e-2)" "unprognostic (5.07e-2)" "unprognostic (6.65e-2)" "unprognostic (1.19e-1)" "unprognostic (4.84e-2)" GPR139 PGR3 ENSG00000180269 "G protein-coupled receptor 139" Q6DWJ6 16 20028239-20073890 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 5 "brain: 2.2" "Cell type enriched" "Detected in some" 5 "Lactotrophs: 66.6" "Cell type enhanced" "Detected in some" "mammillary body: 41.7;medium spiny neuron: 20.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pituitary gland - Lactotropes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA046596 Uncertain NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 27: Breast cancer - Unknown function" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" "HPA046596: " "unprognostic (4.43e-1)" "unprognostic (7.41e-2)" GPR141 PGR13 ENSG00000187037 "G protein-coupled receptor 141" Q7Z602 7 37683766-37833788 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "bone marrow: 24.5" "Cell type enhanced" "Detected in some" "cDC: 2.7;Hematopoietic stem cells: 3.9;Macrophages: 1.8;Mast cells: 8.6;Megakaryocyte-Erythroid progenitors: 1.9;Monocyte progenitors: 4.2;monocytes: 3.5;Neutrophil progenitors: 10.9;Neutrophils: 10.0;NK-cells: 4.1" "Group enriched" "Detected in some" 10 "central nervous system macrophage: 1.0;leukocyte: 1.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 11.1;eosinophil: 8.0;gdT-cell: 4.4;memory CD8 T-cell: 4.3;myeloid DC: 5.9;naive CD8 T-cell: 2.9;neutrophil: 10.8" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Leukemia: 4.8" "Adipose visceral - Neutrophils, Lung - Neutrophils_2, Spleen - Neutrophils_2" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 15: Bone marrow - Innate immune response" "Cluster 30: White matter - Myelination" "Cluster 49: HMC-1 - Innate immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 13 "unprognostic (1.42e-2)" "unprognostic (2.71e-1)" "unprognostic (6.55e-2)" "unprognostic (1.95e-1)" "unprognostic (5.60e-3)" "unprognostic (1.32e-1)" "unprognostic (2.04e-2)" "unprognostic (1.38e-1)" "unprognostic (1.11e-2)" "unprognostic (3.47e-2)" "unprognostic (1.26e-1)" "unprognostic (2.05e-1)" "unprognostic (2.35e-1)" "unprognostic (4.79e-2)" "unprognostic (3.83e-1)" "unprognostic (9.13e-2)" "unprognostic (1.11e-2)" "unprognostic (2.73e-1)" "unprognostic (2.59e-1)" "unprognostic (4.73e-1)" GPR142 PGR2 ENSG00000257008 "G protein-coupled receptor 142" Q7Z601 17 74367458-74372600 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "stomach 1: 1.7" "Cell type enhanced" "Detected in single" "Foveolar cells: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Alpha cells, Prostate - Endothelial cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA031392 Uncertain Uncertain "Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 60: Stomach - Digestion" "Cluster 49: Hindbrain - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" "Plasma membrane, Cytosol" "Cell Junctions" "HPA031392: " GPR143 OA1 ENSG00000101850 "G protein-coupled receptor 143" P51810 X 9725346-9786297 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Albinism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 23.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 56.9;Melanocytes: 321.7;Migrating cytotrophoblasts: 44.8;Retinal pigment epithelial cells: 123.6" "Cell type enhanced" "Detected in many" "astrocyte: 22.4;choroid plexus epithelial cell: 23.4" "Cancer enriched" "Detected in all" 5 "Skin Cutaneous Melanoma (TCGA): 198.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "basophil: 3.1" "Lineage enriched" "Detected in single" 19 "granulocytes: 3.1" "Cancer enriched" "Detected in many" 5 "skin cancer: 74.2" "Adipose visceral - Mesothelial cells, Skin - Melanocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA003648 Enhanced Supported "Nucleoplasm,Nuclear bodies,Golgi apparatus,Plasma membrane" NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 61: Schwann cells & Melanocytes - Mixed function" 4 "Plasma membrane" "Nucleoplasm, Nuclear bodies, Golgi apparatus" "HPA003648: " "unprognostic (3.23e-2)" "unprognostic (9.14e-3)" "unprognostic (1.08e-1)" "unprognostic (8.79e-2)" "unprognostic (1.70e-1)" "unprognostic (7.17e-2)" "unprognostic (2.94e-3)" "unprognostic (4.24e-2)" "unprognostic (8.59e-3)" "unprognostic (1.61e-1)" "unprognostic (7.28e-2)" "unprognostic (6.95e-3)" "unprognostic (1.63e-1)" "unprognostic (1.36e-1)" "potential prognostic favorable (5.45e-4)" "unprognostic (2.03e-2)" "unprognostic (2.38e-1)" "unprognostic (5.35e-2)" "unprognostic (1.47e-1)" "unprognostic (2.58e-1)" "unprognostic (4.94e-1)" "unprognostic (8.72e-2)" "unprognostic (7.08e-2)" "unprognostic (1.20e-1)" "unprognostic (6.73e-3)" "unprognostic (4.78e-3)" "unprognostic (3.18e-1)" "unprognostic (5.29e-2)" "unprognostic (2.50e-1)" "unprognostic (1.80e-1)" "unprognostic (1.10e-1)" GPR146 PGR8 ENSG00000164849 "G protein-coupled receptor 146" Q96CH1 7 1044546-1059261 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "adipose tissue: 43.1" "Cell type enhanced" "Detected in many" "Breast lactating cells: 63.2;Extravillous trophoblasts: 389.5;Lymphatic endothelial cells: 74.6;Migrating cytotrophoblasts: 51.1;Syncytiotrophoblasts: 112.3;Vascular endothelial cells: 54.5" "Cell type enhanced" "Detected in many" "endothelial cell: 52.2;oligodendrocyte precursor cell: 17.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "eosinophil: 95.4;naive CD4 T-cell: 25.6" "Group enriched" "Detected in many" 4 "granulocytes: 95.4;T-cells: 25.6" "Low cancer specificity" "Detected in many" "Prostate - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" "unprognostic (5.67e-2)" "unprognostic (7.61e-2)" "unprognostic (8.46e-2)" "unprognostic (5.34e-2)" "unprognostic (4.76e-3)" "unprognostic (1.04e-1)" "unprognostic (3.00e-3)" "unprognostic (7.95e-2)" "unprognostic (2.75e-1)" "unprognostic (1.79e-1)" "unprognostic (4.62e-3)" "unprognostic (5.08e-3)" "unprognostic (5.65e-2)" "unprognostic (5.94e-2)" "unprognostic (8.20e-3)" "unprognostic (5.69e-2)" "unprognostic (1.22e-1)" "unprognostic (2.31e-3)" "unprognostic (1.08e-1)" "unprognostic (2.90e-2)" "unprognostic (1.18e-2)" "unprognostic (1.14e-2)" "unprognostic (1.12e-1)" "unprognostic (1.76e-1)" "unprognostic (2.42e-2)" "unprognostic (6.47e-3)" "unprognostic (1.92e-2)" "unprognostic (1.76e-3)" "unprognostic (9.81e-2)" "unprognostic (1.68e-1)" "unprognostic (1.73e-1)" GPR148 PGR6 ENSG00000173302 "G protein-coupled receptor 148" Q8TDV2 2 130729070-130730336 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046655, HPA060527" Uncertain Supported "Plasma membrane" NA NA "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 109: Neurons - Neuronal signaling" "Plasma membrane" "HPA046655: , HPA060527: " GPR149 "IEDA, PGR10, R35" ENSG00000174948 "G protein-coupled receptor 149" Q86SP6 3 154334943-154430190 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.4;seminal vesicle: 1.3" "Cell type enhanced" "Detected in some" "Brain inhibitory neurons: 171.3;Other brain neurons: 36.0;Retinal ganglion cells: 50.2;Sertoli cells: 26.3;Somatotrophs: 266.2;Thyrotrophs: 126.5" "Cell type enhanced" "Detected in many" "eccentric medium spiny neuron: 282.1;lower rhombic lip: 163.9;medium spiny neuron: 393.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "prostate cancer: 1.0" "Pituitary gland - Somatotropes" "Region enhanced" "Detected in many" "basal ganglia: 15.0" "Low region specificity" "Detected in many" HPA018020 Uncertain NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" "HPA018020: " GPR15 ENSG00000154165 "G protein-coupled receptor 15" P49685 3 98531978-98534681 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "intestine: 29.4" "Group enriched" "Detected in some" 6 "NK-cells: 12.1;Plasma cells: 24.6;T-cells: 19.9" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 6 "memory B-cell: 3.6;memory CD4 T-cell: 10.8;memory CD8 T-cell: 5.1;T-reg: 12.2" "Group enriched" "Detected in many" 26 "B-cells: 3.6;T-cells: 12.2" "Cancer enhanced" "Detected in many" "lymphoma: 31.6" "Adipose visceral - T-cells, Breast - Plasma cells, Minor Salivary Gland - Plasma cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA013775 Approved NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 17: Intestine - Digestion" "Cluster 30: White matter - Myelination" "Cluster 55: Lymphoma - Immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" "HPA013775: " "unprognostic (3.12e-1)" "unprognostic (3.18e-1)" "potential prognostic favorable (1.97e-6)" "unprognostic (7.95e-2)" "unprognostic (1.36e-3)" "unprognostic (9.10e-2)" "unprognostic (2.82e-1)" "unprognostic (3.22e-2)" "unprognostic (1.80e-2)" "unprognostic (1.13e-1)" GPR150 PGR11 ENSG00000178015 "G protein-coupled receptor 150" Q8NGU9 5 95620087-95622142 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.5;pancreas: 6.5" "Cell type enhanced" "Detected in some" "Early spermatids: 3.3;Extravillous trophoblasts: 8.5;Gastric chief cells: 6.6;Hofbauer cells: 6.4;Innate lymphoid cells: 2.8;Late primary spermatocytes: 5.8;Mast cells: 2.6;Mucous neck cells: 2.4;Oocytes: 4.6" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Low region specificity" "Detected in some" HPA026635 Uncertain NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 53: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" "HPA026635: " "unprognostic (2.56e-1)" GPR151 "GALR4, PGR7" ENSG00000173250 "G protein-coupled receptor 151" Q8TDV0 5 146513144-146516190 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 2.1;Late spermatids: 1.2;Thymic myoid cells: 1.4" "Cell type enhanced" "Detected in some" "hippocampal CA1-3: 1.1;splatter: 3.1" "Not detected" "Not detected" "Region enriched" "Detected in single" 22 "midbrain: 17.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in many" 19 "thalamus: 30.6" "Region enriched" "Detected in single" 9 "thalamus: 6.1" HPA065728 Supported NA NA "Cluster 46: Brainstem - Mixed function" "Cluster 20: Myeloma - Immune response" "Cluster 98: Neurons - Neurotransmission & signaling" 35 "HPA065728: " GPR152 PGR5 ENSG00000175514 "G protein-coupled receptor 152" Q8TDT2 11 67451301-67452729 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA035078 Uncertain NA NA "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 164 "HPA035078: " "unprognostic (9.22e-2)" GPR153 PGR1 ENSG00000158292 "G protein-coupled receptor 153" Q6NV75 1 6247353-6261098 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Epididymal efferent duct absorptive cells: 29.4;Epididymal principal cells: 27.3;Goblet cells: 109.9;Hepatocytes: 45.2;Lactotrophs: 34.8;Ocular epithelial cells: 54.4;Retinal amacrine cells: 53.0;Retinal ganglion cells: 30.9;Retinal horizontal cells: 58.1" "Cell type enhanced" "Detected in many" "midbrain-derived inhibitory: 29.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 36.0" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Pituitary gland - Lactotropes, Prostate - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007159 Approved NA NA "Cluster 75: Ovary - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 70: Intestinal goblet cells - Mucin production" "HPA007159: " "unprognostic (5.41e-2)" "unprognostic (1.90e-2)" "unprognostic (1.24e-1)" "unprognostic (1.35e-2)" "unprognostic (6.58e-2)" "unprognostic (1.07e-1)" "unprognostic (6.66e-3)" "unprognostic (5.81e-2)" "unprognostic (7.74e-2)" "unprognostic (2.14e-1)" "unprognostic (2.79e-3)" "unprognostic (1.89e-1)" "unprognostic (4.15e-2)" "unprognostic (1.01e-1)" "unprognostic (2.69e-2)" "potential prognostic unfavorable (4.14e-4)" "unprognostic (4.09e-2)" "unprognostic (2.45e-2)" "potential prognostic unfavorable (1.18e-4)" "unprognostic (2.07e-2)" "unprognostic (1.35e-1)" "unprognostic (3.92e-2)" "unprognostic (2.80e-2)" "unprognostic (3.26e-2)" "unprognostic (2.01e-1)" "unprognostic (6.19e-2)" "unprognostic (1.59e-1)" "unprognostic (1.91e-1)" "unprognostic (1.30e-1)" "unprognostic (9.86e-2)" "unprognostic (2.72e-2)" GPR155 "DEP.7, DEPDC3, FLJ31819, PGR22" ENSG00000163328 "G protein-coupled receptor 155" Q7Z3F1 2 174431571-174487094 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 65.2;stomach 1: 49.6" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 393.6;Brain inhibitory neurons: 192.5;Choroid plexus epithelial cells: 876.0;Melanocytes: 404.1;Neutrophils: 201.9;Parietal cells: 606.4;Proximal tubule cells: 186.4;Schwann cells: 363.9" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 730.7" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "choroid plexus: 194.4" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Kidney - Proximal tubular cells, Prostate - Smooth muscle cells, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036159, HPA057384" Approved NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 1 "HPA036159: , HPA057384: " "unprognostic (8.98e-3)" "unprognostic (1.33e-1)" "unprognostic (7.11e-2)" "unprognostic (2.68e-1)" "unprognostic (1.26e-1)" "unprognostic (1.17e-1)" "unprognostic (2.34e-2)" "unprognostic (3.08e-1)" "unprognostic (6.68e-2)" "unprognostic (1.22e-2)" "unprognostic (2.50e-3)" "unprognostic (7.69e-2)" "unprognostic (2.22e-1)" "unprognostic (1.35e-1)" "potential prognostic favorable (1.24e-4)" "unprognostic (1.09e-3)" "unprognostic (9.19e-2)" "unprognostic (2.30e-1)" "unprognostic (1.45e-1)" "unprognostic (3.01e-2)" "unprognostic (9.31e-3)" "unprognostic (5.49e-2)" "unprognostic (2.47e-1)" "unprognostic (4.76e-2)" "unprognostic (1.79e-1)" "unprognostic (2.52e-1)" "unprognostic (1.50e-1)" "unprognostic (3.27e-2)" "unprognostic (1.53e-1)" "unprognostic (7.55e-3)" "unprognostic (1.68e-2)" GPR156 "GABABL, PGR28" ENSG00000175697 "G protein-coupled receptor 156" Q8NFN8 3 120164645-120285222 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "testis: 2.5" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 34.8;Early spermatids: 30.4;Ependymal cells: 32.4;Late primary spermatocytes: 21.5;Late spermatids: 38.1;Müller glia: 34.3;Oligodendrocyte progenitor cells: 20.6;Retinal ganglion cells: 30.9;Undifferentiated spermatogonia: 26.9" "Cell type enhanced" "Detected in many" "ependymal cell: 31.0;oligodendrocyte precursor cell: 27.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Skin - Inner root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA028642, HPA028644" Uncertain Supported "Plasma membrane" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 109: Neurons - Neuronal signaling" "Plasma membrane" "HPA028642: , HPA028644: " "unprognostic (4.16e-3)" GPR157 FLJ12132 ENSG00000180758 "G protein-coupled receptor 157" Q5UAW9 1 9100305-9129102 "G-protein coupled receptors, Predicted membrane proteins" Differentiation "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 55.8" "Cell type enhanced" "Detected in many" "cDC: 201.3;Choroid plexus epithelial cells: 82.2;Esophageal apical cells: 220.2;Esophageal basal cells: 80.8;Esophageal suprabasal cells: 132.7;Myonuclei: 114.4;Suprabasal keratinocytes: 76.4;Syncytiotrophoblasts: 114.1;Urothelial cells: 120.2" "Cell type enriched" "Detected in many" 6 "choroid plexus epithelial cell: 75.1" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "choroid plexus: 23.9" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA028697, HPA054948" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 82: Dendritic cells - Antigen presentation" Cytosol "Plasma membrane" "HPA028697: , HPA054948: " "unprognostic (2.28e-2)" "potential prognostic unfavorable (7.51e-4)" "unprognostic (1.56e-1)" "unprognostic (1.09e-3)" "unprognostic (1.04e-1)" "unprognostic (2.43e-1)" "unprognostic (2.33e-2)" "potential prognostic unfavorable (1.72e-5)" "unprognostic (2.16e-1)" "unprognostic (7.94e-2)" "unprognostic (7.29e-2)" "unprognostic (1.52e-1)" "unprognostic (9.79e-2)" "unprognostic (1.99e-2)" "unprognostic (1.32e-1)" "unprognostic (9.50e-2)" "unprognostic (2.91e-1)" "unprognostic (9.32e-3)" "unprognostic (9.54e-2)" "unprognostic (1.20e-1)" "unprognostic (3.74e-1)" "unprognostic (1.51e-2)" "unprognostic (1.21e-1)" "unprognostic (9.69e-2)" "unprognostic (6.09e-2)" "potential prognostic favorable (8.03e-4)" "unprognostic (3.39e-2)" "unprognostic (1.25e-2)" "unprognostic (4.83e-1)" "unprognostic (5.19e-2)" "unprognostic (3.08e-2)" GPR158 KIAA1136 ENSG00000151025 "G protein-coupled receptor 158" Q5T848 10 25174802-25602229 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 10.1;retina: 4.2" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 423.7;Brain inhibitory neurons: 537.9;Corticotrophs: 201.2;Gonadotrophs: 278.9;Lactotrophs: 853.1;Müller glia: 237.2;Oligodendrocyte progenitor cells: 427.9;Other brain neurons: 365.6;Retinal amacrine cells: 336.3;Retinal ganglion cells: 262.7;Retinal horizontal cells: 1149.9;Somatotrophs: 465.4;Thyrotrophs: 379.5" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 2.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "prostate cancer: 10.9" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013185 Uncertain NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 15: Non-specific - Transcription" "Cluster 60: Prostate cancer - Unknown function" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" "HPA013185: " "unprognostic (3.98e-2)" "unprognostic (4.95e-2)" "unprognostic (5.05e-3)" "unprognostic (1.13e-1)" "unprognostic (1.61e-2)" "unprognostic (1.27e-1)" GPR15LG "AP-57, C10orf99, CSBF, FLJ21763, GPR15L, RLLV1833, UNQ1833" ENSG00000188373 "G protein-coupled receptor 15 ligand" Q6UWK7 10 84173801-84185294 "Predicted secreted proteins" Chemotaxis "Antibiotic, Antimicrobial, Cytokine" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "cervix: 94.1;esophagus: 205.1;intestine: 257.9;vagina: 123.1" "Cell type enhanced" "Detected in some" "Colonocytes: 963.0;Enteric stem cells: 262.8;Enteric transient amplifying cells: 394.3;Enterocytes: 327.6;Esophageal apical cells: 626.7;Esophageal basal cells: 399.7;Esophageal suprabasal cells: 2234.0;Goblet cells: 202.1;Suprabasal keratinocytes: 261.3;Urothelial cells: 275.8" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 169.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "colorectal cancer: 26.7;head and neck cancer: 7.5" "Colon - Colon enterocytes, Prostate - Urothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA050920 Enhanced "Secreted in other tissues" Cytokine NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 85: Squamous epithelial cells - Keratinization" "HPA050920: " "unprognostic (1.30e-1)" "unprognostic (8.16e-2)" "unprognostic (2.85e-1)" "unprognostic (2.25e-3)" "unprognostic (1.30e-2)" "unprognostic (6.49e-2)" "potential prognostic unfavorable (4.94e-5)" "unprognostic (4.28e-2)" "unprognostic (2.07e-2)" "unprognostic (2.00e-1)" "unprognostic (9.91e-2)" "unprognostic (2.59e-1)" "unprognostic (1.75e-1)" "unprognostic (1.42e-1)" "unprognostic (1.96e-1)" "unprognostic (1.48e-1)" "unprognostic (3.66e-1)" "unprognostic (2.05e-1)" GPR160 "GPCR1, GPCR150" ENSG00000173890 "G protein-coupled receptor 160" Q9UJ42 3 170037995-170085392 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 102.0;parathyroid gland: 203.7;retina: 96.9" "Cell type enhanced" "Detected in many" "Enteric stem cells: 293.5;Enteric transient amplifying cells: 238.9;Enterocytes: 406.4;Gastric chief cells: 338.5;Gastric progenitor cells: 230.7;Mucous neck cells: 210.2;Neuroendocrine cells: 277.7;Neutrophil progenitors: 252.4;Neutrophils: 407.0;Paneth cells: 243.6;Rod photoreceptor cells: 675.4" "Cell type enriched" "Detected in many" 4 "central nervous system macrophage: 41.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Liver - Vascular endothelial cells, Prostate - Prostate glandular cells, Skeletal muscle - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA006970 Approved Supported "Plasma membrane" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 42: Retina - Visual perception" "Cluster 55: Non-specific - Transcription" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 79: Photoreceptor cells - Phototransduction" 2 "Plasma membrane" "HPA006970: " "potential prognostic favorable (4.25e-5)" "unprognostic (5.67e-2)" "unprognostic (2.17e-1)" "unprognostic (7.78e-2)" "unprognostic (6.28e-2)" "unprognostic (6.02e-2)" "unprognostic (7.42e-2)" "unprognostic (3.55e-1)" "unprognostic (2.58e-1)" "potential prognostic unfavorable (1.18e-5)" "potential prognostic favorable (1.23e-8)" "unprognostic (1.17e-2)" "unprognostic (9.73e-3)" "unprognostic (1.06e-2)" "unprognostic (6.81e-2)" "unprognostic (1.40e-2)" "unprognostic (4.91e-2)" "unprognostic (2.55e-3)" "unprognostic (9.29e-2)" "unprognostic (2.54e-1)" "unprognostic (1.54e-1)" "unprognostic (2.14e-2)" "unprognostic (4.24e-2)" "unprognostic (5.51e-2)" "potential prognostic favorable (5.75e-4)" "unprognostic (2.08e-1)" "unprognostic (1.18e-1)" "unprognostic (4.17e-1)" "unprognostic (1.96e-1)" "unprognostic (4.26e-2)" "unprognostic (5.23e-3)" GPR161 RE2 ENSG00000143147 "G protein-coupled receptor 161" Q8N6U8 1 168079542-168137667 "Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins, Transporters" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 24.0;smooth muscle: 25.7" "Cell type enhanced" "Detected in many" "Astrocytes: 26.7;Endometrial stromal cells: 26.2;Pericytes: 25.8;Podocytes: 36.1;Retinal horizontal cells: 100.2;Smooth muscle cells: 36.3;Vascular smooth muscle cells: 28.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Prostate - Smooth muscle cells, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA015576, HPA072047" Uncertain Approved "Primary cilium,Primary cilium transition zone" NA No "Cluster 75: Ovary - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 110: Mural cells - ECM organization" 6 "Primary cilium" "Primary cilium transition zone" "HPA015576: , HPA072047: " "unprognostic (1.77e-1)" "unprognostic (2.64e-1)" "unprognostic (1.24e-1)" "unprognostic (2.02e-2)" "unprognostic (1.40e-2)" "unprognostic (1.48e-1)" "unprognostic (2.13e-1)" "unprognostic (3.71e-3)" "unprognostic (1.49e-1)" "unprognostic (1.17e-1)" "unprognostic (1.23e-1)" "unprognostic (3.88e-2)" "unprognostic (2.22e-3)" "unprognostic (1.14e-1)" "unprognostic (1.16e-2)" "unprognostic (3.32e-2)" "unprognostic (2.40e-1)" "unprognostic (9.82e-2)" "unprognostic (1.32e-1)" "unprognostic (1.42e-1)" "unprognostic (8.70e-3)" "unprognostic (1.65e-1)" "unprognostic (2.02e-2)" "unprognostic (4.14e-1)" "unprognostic (3.87e-3)" "unprognostic (4.29e-2)" "unprognostic (3.98e-2)" "unprognostic (3.08e-2)" "unprognostic (1.95e-1)" "unprognostic (3.84e-1)" GPR162 "A-2, GRCA" ENSG00000250510 "G protein-coupled receptor 162" Q16538 12 6821624-6829972 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 143.5;choroid plexus: 72.9" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 43.5;Brain inhibitory neurons: 30.0;Ependymal cells: 59.4;Fallopian tube ciliated cells: 69.3;Müller glia: 38.2;Oligodendrocyte progenitor cells: 37.7;Other brain neurons: 34.3;Respiratory ciliated cells: 114.0;Retinal amacrine cells: 54.7;Retinal bipolar cells: 48.3;Retinal horizontal cells: 24.0" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 5 "Glioblastoma Multiforme (TCGA): 43.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 17.5" "Group enriched" "Detected in many" 6 "granulocytes: 17.5;monocytes: 6.9" "Cancer enhanced" "Detected in many" "Rhabdoid: 18.0" "Adrenal gland - Adrenal medulla cells, Lung - Respiratory ciliated cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055135 Enhanced Approved "Centriolar satellite" "Intracellular and membrane" Receptor NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 27: Cerebellum - Synaptic function" "Cluster 51: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 2 "Centriolar satellite" "HPA055135: " "unprognostic (4.10e-2)" "unprognostic (1.38e-1)" "unprognostic (2.64e-2)" "unprognostic (2.74e-2)" "unprognostic (4.88e-3)" "unprognostic (2.49e-2)" "unprognostic (8.99e-2)" "unprognostic (8.09e-3)" "unprognostic (1.54e-1)" "unprognostic (5.08e-2)" "potential prognostic unfavorable (3.43e-4)" "unprognostic (8.97e-2)" "unprognostic (6.39e-2)" "unprognostic (5.79e-2)" "unprognostic (2.45e-2)" "unprognostic (5.76e-2)" "unprognostic (1.93e-1)" "unprognostic (2.08e-1)" "unprognostic (4.01e-1)" "unprognostic (5.32e-2)" "unprognostic (7.25e-2)" "potential prognostic favorable (2.06e-5)" "unprognostic (3.77e-2)" "unprognostic (3.02e-2)" "unprognostic (2.81e-1)" "unprognostic (1.59e-1)" "unprognostic (3.65e-2)" "unprognostic (1.33e-2)" "unprognostic (1.61e-1)" "unprognostic (2.84e-1)" "unprognostic (8.37e-2)" GPR17 ENSG00000144230 "G protein-coupled receptor 17" Q13304 2 127645864-127652639 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 35.3" "Group enriched" "Detected in some" 20 "Cardiomyocytes: 76.6;Oligodendrocyte progenitor cells: 131.4;Oligodendrocytes: 264.3" "Cell type enriched" "Detected in some" 10 "committed oligodendrocyte precursor: 1418.6" "Cancer enriched" "Detected in some" 5 "Glioblastoma Multiforme (TCGA): 5.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 19 "naive B-cell: 1.9" "Lineage enriched" "Detected in single" 19 "B-cells: 1.9" "Cancer enhanced" "Detected in some" "Adrenocortical cancer: 4.0" "Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029766 Enhanced Supported Approved Vesicles NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" Vesicles "HPA029766: " "unprognostic (4.58e-2)" "unprognostic (8.58e-2)" "unprognostic (3.28e-1)" "unprognostic (3.14e-2)" "unprognostic (1.34e-1)" "unprognostic (2.33e-3)" "potential prognostic favorable (7.20e-4)" "unprognostic (9.17e-2)" "unprognostic (3.62e-2)" GPR171 H963 ENSG00000174946 "G protein-coupled receptor 171" O14626 3 151197832-151203216 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 12.1;lymphoid tissue: 20.1" "Cell type enhanced" "Detected in some" "Hematopoietic stem cells: 15.5;Innate lymphoid cells: 32.1;Megakaryocyte progenitors: 13.5;Müller glia: 12.2;NK-cells: 44.1;T-cells: 144.2;Thymocytes: 10.2" "Cell type enriched" "Detected in many" 4 "leukocyte: 47.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 110.6" "Lineage enriched" "Detected in many" 15 "T-cells: 110.6" "Group enriched" "Detected in some" 39 "Leukemia: 2.3;lymphoma: 6.0;Myeloma: 4.1" "Adrenal gland - T-cells, Liver - T-cells, Prostate - T-cells, Skin - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA067323 Supported Approved "Vesicles,Plasma membrane" NA NA "Cluster 27: T-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 23: Choroid plexus - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" 1 "Vesicles, Plasma membrane" "HPA067323: " "unprognostic (1.32e-1)" "potential prognostic favorable (2.18e-4)" "unprognostic (1.73e-3)" "potential prognostic favorable (2.34e-4)" "unprognostic (2.16e-2)" "unprognostic (1.40e-2)" "unprognostic (2.24e-2)" "potential prognostic favorable (2.02e-4)" "unprognostic (8.16e-3)" "unprognostic (2.10e-1)" "potential prognostic unfavorable (4.85e-4)" "unprognostic (5.58e-3)" "unprognostic (1.75e-2)" "unprognostic (4.83e-1)" "unprognostic (3.51e-1)" "unprognostic (8.72e-2)" "unprognostic (3.61e-2)" "unprognostic (2.28e-1)" "unprognostic (3.04e-1)" "unprognostic (2.51e-3)" "unprognostic (2.19e-2)" "unprognostic (2.33e-1)" "unprognostic (4.25e-1)" "unprognostic (1.71e-1)" "unprognostic (8.71e-2)" "unprognostic (4.34e-1)" GPR173 SREB3 ENSG00000184194 "G protein-coupled receptor 173" Q9NS66 X 53048789-53080615 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.9;pituitary gland: 16.6" "Cell type enhanced" "Detected in many" "Astrocytes: 100.0;Bergmann glia: 90.9;Endometrial stromal cells: 73.0;Fibro-adipogenic progenitors: 66.9;Gonadotrophs: 69.9;Lactotrophs: 142.3;Leydig cells: 80.8;Oligodendrocyte progenitor cells: 82.5;Oligodendrocytes: 65.1;Peritubular myoid cells: 86.2;Pituicytes/FSCs: 89.9;Podocytes: 76.4;Somatotrophs: 99.4;Thyrotrophs: 78.9" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 16.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "basophil: 3.9" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.9" "Cancer enhanced" "Detected in many" "Neuroblastoma: 31.5" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Colon - Enteric glia cells, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003905 Approved "Plasma membrane,Cytosol" NA NA "Cluster 65: Brain - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 34 "Plasma membrane, Cytosol" "HPA003905: " "unprognostic (4.47e-2)" "unprognostic (8.94e-2)" "unprognostic (3.28e-2)" "unprognostic (9.39e-2)" "potential prognostic unfavorable (1.70e-4)" "unprognostic (1.51e-1)" "unprognostic (1.37e-1)" "potential prognostic favorable (3.26e-5)" "unprognostic (6.12e-2)" "potential prognostic unfavorable (4.22e-6)" "unprognostic (6.99e-3)" "unprognostic (8.78e-2)" "unprognostic (4.39e-2)" "unprognostic (3.49e-2)" "unprognostic (1.04e-1)" "unprognostic (5.33e-2)" "unprognostic (2.51e-2)" "unprognostic (7.15e-2)" "unprognostic (2.44e-3)" "unprognostic (8.18e-3)" "unprognostic (2.78e-1)" "unprognostic (8.71e-2)" "unprognostic (1.32e-1)" "unprognostic (2.58e-1)" "unprognostic (3.01e-2)" "unprognostic (3.08e-2)" "unprognostic (1.25e-1)" "unprognostic (7.32e-2)" GPR174 FKSG79 ENSG00000147138 "G protein-coupled receptor 174" Q9BXC1 X 79144688-79175318 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 15.7" "Cell type enhanced" "Detected in some" "B-cells: 34.2;Hematopoietic stem cells: 9.7;Innate lymphoid cells: 26.7;NK-cells: 71.8;pDCs: 17.9;Platelets: 9.8;T-cells: 105.1;Thymocytes: 39.0" "Cell type enriched" "Detected in some" 100 "leukocyte: 204.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Leukemia: 11.2;lymphoma: 3.2" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Minor Salivary Gland - T-cells, Pancreas - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA041025, HPA058306" Enhanced Approved "Vesicles,Plasma membrane,Centriolar satellite" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 6: Non-specific - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" "Plasma membrane" "Vesicles, Centriolar satellite" "HPA041025: , HPA058306: " "unprognostic (5.83e-3)" "unprognostic (4.60e-2)" "unprognostic (3.41e-3)" "unprognostic (2.31e-1)" "unprognostic (1.80e-1)" "unprognostic (1.60e-1)" "unprognostic (4.41e-1)" "unprognostic (2.23e-2)" "unprognostic (1.26e-3)" "unprognostic (2.78e-1)" "unprognostic (1.34e-1)" "unprognostic (1.66e-1)" "unprognostic (1.00e-1)" "unprognostic (1.44e-2)" "unprognostic (7.01e-2)" GPR176 Gm1012 ENSG00000166073 "G protein-coupled receptor 176" Q14439 15 39799008-39920266 "G-protein coupled receptors, Predicted membrane proteins" "Biological rhythms" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 34.6;brain: 21.9" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 95.7;Brain excitatory neurons: 48.4;Brain inhibitory neurons: 58.3;Epicardial cells: 47.8;Hepatic stellate cells: 109.7;Oligodendrocyte progenitor cells: 53.7;Other brain neurons: 49.4;Pericytes: 60.1;Plasma cells: 52.8;Retinal amacrine cells: 60.0;Salivary myoepithelial cells: 79.5;Sertoli cells: 43.1;Somatotrophs: 82.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Adrenal medulla cells, Breast - Endothelial cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039943, HPA039979" Approved NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 1: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 110: Mural cells - ECM organization" "HPA039943: , HPA039979: " "unprognostic (5.45e-2)" "unprognostic (4.04e-2)" "unprognostic (1.43e-1)" "unprognostic (3.44e-1)" "unprognostic (4.56e-2)" "unprognostic (1.28e-1)" "unprognostic (2.12e-1)" "unprognostic (8.94e-3)" "unprognostic (2.39e-2)" "unprognostic (1.60e-1)" "unprognostic (5.08e-3)" "unprognostic (5.30e-2)" "unprognostic (6.56e-2)" "unprognostic (3.03e-2)" "unprognostic (1.68e-1)" "unprognostic (1.24e-3)" "potential prognostic unfavorable (7.58e-5)" "unprognostic (1.41e-1)" "unprognostic (1.90e-1)" "unprognostic (4.78e-3)" "potential prognostic unfavorable (5.73e-4)" "unprognostic (2.76e-2)" "unprognostic (1.55e-1)" "unprognostic (1.59e-2)" "unprognostic (2.48e-1)" "unprognostic (7.84e-3)" "unprognostic (8.23e-2)" "potential prognostic unfavorable (9.91e-6)" "unprognostic (1.85e-1)" "unprognostic (2.42e-1)" "unprognostic (1.14e-1)" GPR179 "CSNB1E, GPR158L1" ENSG00000277399 "G protein-coupled receptor 179" 17 38324571-38343956 "Human disease related genes, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 8 "retina: 12.8" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 1.8;Brain inhibitory neurons: 2.5;Other brain neurons: 3.8;Retinal bipolar cells: 2.3" "Cell type enhanced" "Detected in many" "deep-layer near-projecting: 12.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA017885 Uncertain NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 98: Neurons - Neurotransmission & signaling" "HPA017885: " GPR18 ENSG00000125245 "G protein-coupled receptor 18" Q14330 13 99254732-99261744 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 9.1;lymphoid tissue: 36.3;testis: 12.2" "Cell type enhanced" "Detected in many" "B-cells: 58.4;Cardiomyocytes: 67.2;Early spermatids: 231.6;Late spermatids: 301.2;NK-cells: 31.4;T-cells: 31.9" "Cell type enhanced" "Detected in many" "leukocyte: 13.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 4 "B-cells: 65.5;NK-cells: 53.1;T-cells: 42.0" "Group enriched" "Detected in some" 17 "Leukemia: 6.7;lymphoma: 26.6" "Adipose visceral - T-cells, Breast - T-cells, Kidney - T-cells, Spleen - B-cells (Spleen), Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA013873 Enhanced NA NA "Cluster 24: Non-specific - Transcription" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" "HPA013873: " "validated prognostic favorable (2.83e-5)" "validated prognostic favorable (6.22e-4)" "unprognostic (7.38e-3)" "unprognostic (3.29e-2)" "unprognostic (2.13e-1)" "potential prognostic favorable (3.32e-4)" "unprognostic (1.64e-1)" "unprognostic (1.59e-1)" "unprognostic (8.56e-2)" "unprognostic (3.87e-2)" "unprognostic (1.42e-2)" "unprognostic (5.68e-2)" "unprognostic (6.40e-2)" GPR180 ITR ENSG00000152749 "G protein-coupled receptor 180" Q86V85 13 94601857-94634661 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047250 Approved Approved "Nucleoplasm,Vesicles,Primary cilium" NA NA 8400 "Cluster 1: T-cells - Unknown function" "Cluster 36: Brain & Liver - Signaling" "Cluster 31: Non-specific - Transcription" "Cluster 19: Non-specific - Unknown function" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 10 Vesicles "Nucleoplasm, Primary cilium" "HPA047250: " "unprognostic (2.33e-1)" "unprognostic (1.69e-2)" "unprognostic (1.03e-1)" "unprognostic (1.38e-1)" "unprognostic (7.55e-2)" "unprognostic (1.72e-1)" "unprognostic (2.36e-1)" "unprognostic (1.21e-1)" "unprognostic (1.26e-1)" "unprognostic (1.86e-2)" "unprognostic (1.14e-2)" "unprognostic (1.09e-1)" "unprognostic (2.04e-2)" "unprognostic (1.33e-2)" "unprognostic (7.02e-2)" "unprognostic (1.90e-2)" "unprognostic (1.55e-2)" "unprognostic (1.03e-1)" "unprognostic (1.35e-1)" "unprognostic (9.02e-2)" "unprognostic (4.20e-2)" "unprognostic (1.08e-1)" "unprognostic (6.74e-3)" "unprognostic (1.53e-1)" "unprognostic (1.17e-1)" "unprognostic (3.24e-1)" "unprognostic (2.11e-2)" "unprognostic (7.74e-2)" "unprognostic (1.61e-1)" "unprognostic (3.18e-2)" "unprognostic (8.40e-2)" GPR182 "ADMR, AM-R, G10D, hrhAMR" ENSG00000166856 "G protein-coupled receptor 182" O15218 12 56994492-56998447 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 16.2;testis: 5.8" "Group enriched" "Detected in some" 4 "Early spermatids: 98.3;Late spermatids: 265.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Smooth muscle cells, Liver - Sinusoid Endothelial cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA027037 Enhanced NA NA "Cluster 5: Spleen - Immune response" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 246 "HPA027037: " "unprognostic (1.19e-1)" GPR183 EBI2 ENSG00000169508 "G protein-coupled receptor 183" P32249 13 99294539-99307399 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Adaptive immunity, Immunity" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 106.3;lymphoid tissue: 79.7" "Cell type enhanced" "Detected in many" "B-cells: 302.1;cDC: 1208.2;Innate lymphoid cells: 192.6;Macrophages: 786.0;Microglia: 155.1;monocytes: 811.1;pDCs: 915.2;T-cells: 230.7" "Group enriched" "Detected in many" 38 "central nervous system macrophage: 216.7;leukocyte: 58.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 1054.3" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Leukemia: 14.9;lymphoma: 23.7;thyroid cancer: 22.6" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Skeletal muscle - Macrophages, Spleen - B-cells (Spleen), Thyroid gland - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB033690, HPA075590" Approved Supported "Nucleoplasm,Plasma membrane,Primary cilium,Primary cilium tip" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 7 "Plasma membrane" "Nucleoplasm, Primary cilium, Primary cilium tip" "CAB033690: , HPA075590: " "unprognostic (1.37e-1)" "unprognostic (1.17e-2)" "unprognostic (9.70e-2)" "unprognostic (8.63e-3)" "unprognostic (9.49e-2)" "unprognostic (6.11e-2)" "unprognostic (1.81e-1)" "unprognostic (1.54e-1)" "unprognostic (3.52e-2)" "unprognostic (1.62e-1)" "unprognostic (3.18e-1)" "unprognostic (2.84e-1)" "unprognostic (9.90e-2)" "unprognostic (1.07e-1)" "unprognostic (1.88e-2)" "unprognostic (5.47e-3)" "unprognostic (1.89e-1)" "unprognostic (1.04e-1)" "unprognostic (3.21e-2)" "unprognostic (6.80e-2)" "unprognostic (1.65e-1)" "unprognostic (7.41e-2)" "unprognostic (2.60e-1)" "unprognostic (2.77e-1)" "unprognostic (1.51e-1)" "unprognostic (4.95e-3)" "unprognostic (2.46e-1)" "unprognostic (3.13e-3)" "unprognostic (2.97e-3)" "unprognostic (5.62e-3)" "unprognostic (2.58e-1)" GPR19 ENSG00000183150 "G protein-coupled receptor 19" Q15760 12 12660890-12696207 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 7.8;pituitary gland: 7.4;testis: 3.7" "Cell type enhanced" "Detected in some" "Astrocytes: 18.0;Bergmann glia: 14.4;Brain excitatory neurons: 20.9;Brain inhibitory neurons: 20.7;Early primary spermatocytes: 29.3;Ependymal cells: 16.9;Gonadotrophs: 15.4;Lactotrophs: 25.5;Oligodendrocyte progenitor cells: 19.5;Other brain neurons: 17.7;Retinal amacrine cells: 17.0;Somatotrophs: 26.3;Thyrotrophs: 17.6" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 12.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 6.4" "Group enriched" "Detected in many" 15 "granulocytes: 2.9;T-cells: 6.4" "Cancer enhanced" "Detected in all" "testis cancer: 26.3" "Colon - Colon enteroendocrine cells, Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013955 Uncertain NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 27: Cerebellum - Synaptic function" "Cluster 2: Neurons - Nucleosome" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" "HPA013955: " "unprognostic (1.04e-1)" "unprognostic (2.71e-1)" "unprognostic (2.25e-1)" "unprognostic (1.89e-1)" "unprognostic (1.30e-2)" "unprognostic (1.14e-1)" "unprognostic (5.74e-3)" "unprognostic (2.17e-1)" "unprognostic (5.44e-3)" "unprognostic (5.86e-2)" "unprognostic (1.49e-1)" "unprognostic (1.52e-1)" "unprognostic (1.08e-1)" "unprognostic (1.30e-3)" "potential prognostic unfavorable (1.69e-5)" "unprognostic (1.86e-2)" "unprognostic (2.74e-1)" "unprognostic (2.73e-1)" "unprognostic (8.72e-2)" "unprognostic (2.37e-1)" GPR20 ENSG00000204882 "G protein-coupled receptor 20" Q99678 8 141356470-141367286 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "blood vessel: 4.1" "Group enriched" "Detected in some" 5 "monocytes: 2.6;Vascular smooth muscle cells: 7.4" "Cell type enriched" "Detected in some" 10 "vascular associated smooth muscle cell: 35.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 18 "intermediate monocyte: 2.6;non-classical monocyte: 4.3" "Lineage enriched" "Detected in single" 22 "monocytes: 4.3" "Low cancer specificity" "Detected in single" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Heart muscle - Smooth muscle cells" "Not detected" "Not detected" "Region enhanced" "Detected in single" "midbrain: 1.1" HPA071337 Supported "Plasma membrane" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 22: Non-specific - Basic cellular functions" "Plasma membrane" "HPA071337: " "unprognostic (3.00e-3)" "unprognostic (1.09e-1)" "unprognostic (1.68e-2)" "potential prognostic favorable (2.33e-5)" "unprognostic (1.29e-1)" "unprognostic (1.99e-1)" "unprognostic (1.21e-1)" GPR21 ENSG00000188394 "G protein-coupled receptor 21" Q99679 9 123033667-123035665 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "blood vessel: 5.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Smooth muscle cells" "Low region specificity" "Detected in many" HPA041651 Uncertain NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "HPA041651: " "unprognostic (3.54e-2)" "unprognostic (8.45e-2)" "unprognostic (1.83e-3)" "unprognostic (1.53e-1)" "unprognostic (8.59e-2)" GPR22 ENSG00000172209 "G protein-coupled receptor 22" Q99680 7 107470018-107475684 "G-protein coupled receptors, Predicted membrane proteins" "Cilium biogenesis/degradation" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 6.5;cervix: 2.3;heart muscle: 7.7" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 41.7;Brain inhibitory neurons: 24.2;Cardiomyocytes: 8.5;Epicardial cells: 6.8;Oligodendrocyte progenitor cells: 8.2;Other brain neurons: 12.4;Retinal bipolar cells: 3.3" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 20 "Neuroblastoma: 1.9" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "hippocampal formation: 79.0" NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 34: Non-specific - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" "unprognostic (2.61e-1)" GPR25 ENSG00000170128 "G protein-coupled receptor 25" O00155 1 200872981-200874178 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 4 "stomach 1: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Stomach Adenocarcinoma (TCGA): 1.8" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "memory CD4 T-cell: 27.6;T-reg: 44.3" "Group enriched" "Detected in many" 57 "B-cells: 14.5;T-cells: 44.3" "Cancer enhanced" "Detected in single" "lymphoma: 2.7" "Lung - T-cells, Prostate - T-cells, Stomach - T-cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 5: Spleen - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 9: T-cells - Adaptive immunity: Regulation" 27 "unprognostic (9.62e-2)" "unprognostic (5.29e-2)" GPR26 ENSG00000154478 "G protein-coupled receptor 26" Q8NDV2 10 123666355-123697399 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 13 "brain: 4.2" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 6.7;Brain inhibitory neurons: 2.7;Fibro-adipogenic progenitors: 1.6;Late spermatids: 1.8;Oocytes: 4.6;Other brain neurons: 4.9;Retinal amacrine cells: 7.8;Retinal horizontal cells: 4.0" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in single" 9 "Breast Invasive Carcinoma (TCGA): 1.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Prostate - Smooth muscle cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Region enhanced" "Detected in all" "cerebral cortex: 81.5" HPA062736 Enhanced NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 109: Neurons - Neuronal signaling" "HPA062736: " "unprognostic (7.66e-2)" "unprognostic (2.47e-1)" "unprognostic (2.42e-2)" GPR27 SREB1 ENSG00000170837 "G protein-coupled receptor 27" Q9NS67 3 71753855-71756496 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.2" "Cell type enriched" "Detected in many" 4 "Neutrophils: 122.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "eosinophil: 2.8;neutrophil: 7.3" "Lineage enriched" "Detected in single" 12 "granulocytes: 7.3" "Low cancer specificity" "Detected in many" "Spleen - Neutrophils_2, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029395 Approved Approved "Nucleoplasm,Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 51: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 24: Neutrophils - Innate immunity signal integration" Nucleoplasm "Plasma membrane, Actin filaments, Cytosol" "HPA029395: " "unprognostic (1.97e-1)" "unprognostic (1.16e-2)" "unprognostic (9.88e-3)" "unprognostic (7.15e-2)" "unprognostic (3.10e-2)" "unprognostic (1.51e-3)" "unprognostic (8.42e-3)" "unprognostic (1.59e-3)" "unprognostic (1.18e-1)" "unprognostic (6.53e-2)" "unprognostic (3.80e-2)" "unprognostic (3.82e-2)" "unprognostic (4.89e-3)" "unprognostic (2.85e-1)" "unprognostic (1.37e-2)" "potential prognostic favorable (3.71e-5)" "unprognostic (6.66e-2)" "unprognostic (3.29e-3)" "unprognostic (9.17e-2)" "unprognostic (2.84e-2)" "unprognostic (5.65e-2)" "unprognostic (2.65e-2)" "unprognostic (2.64e-2)" "unprognostic (1.27e-2)" "unprognostic (1.28e-1)" GPR3 ACCA ENSG00000181773 "G protein-coupled receptor 3" P46089 1 27392622-27395814 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 5.2" "Cell type enhanced" "Detected in some" "Brain inhibitory neurons: 2.5;Epicardial cells: 2.3;Epididymal basal cells: 5.3;Epididymal efferent duct absorptive cells: 2.3;Megakaryocytes: 6.2;Müller glia: 2.9;Neuroendocrine cells: 2.7;Pancreatic islet cells: 3.3;Paneth cells: 7.7;Retinal horizontal cells: 2.0;Schwann cells: 2.1" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 10.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Colon - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" CAB006254 Uncertain NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 45: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 109: Neurons - Neuronal signaling" 2 "CAB006254: " "potential prognostic unfavorable (1.64e-4)" "unprognostic (1.36e-1)" "unprognostic (8.90e-2)" "unprognostic (7.93e-2)" "unprognostic (2.92e-1)" "unprognostic (1.14e-2)" "unprognostic (1.19e-3)" "unprognostic (1.20e-1)" "unprognostic (1.18e-1)" "unprognostic (4.45e-3)" "unprognostic (2.38e-2)" "unprognostic (9.10e-2)" "unprognostic (1.70e-1)" "unprognostic (9.50e-3)" "unprognostic (7.96e-2)" "unprognostic (1.70e-2)" "unprognostic (3.46e-1)" "unprognostic (6.82e-2)" "unprognostic (1.27e-1)" "unprognostic (7.07e-2)" "unprognostic (4.19e-2)" GPR31 "12-HETER, HETER1" ENSG00000120436 "G protein-coupled receptor 31" O00270 6 167155247-167157980 "G-protein coupled receptors, Predicted membrane proteins" "Lipid metabolism" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.3" "Cell type enhanced" "Detected in some" "cDC: 3.4;Epididymal principal cells: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA014014, HPA027108" Uncertain NA NA "Cluster 18: Lymphoid tissue - Immune response" "Cluster 82: Dendritic cells - Antigen presentation" "HPA014014: , HPA027108: " "unprognostic (3.74e-2)" GPR32 RVDR1 ENSG00000142511 "G protein-coupled receptor 32" O75388 19 50770464-50771732 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 32 "parathyroid gland: 54.6" "Group enriched" "Detected in some" 5 "Extravillous trophoblasts: 8.0;Syncytiotrophoblasts: 2.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 30 "testis cancer: 2.9" "Not detected" "Not detected" NA NA "Cluster 69: Parathyroid gland - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" GPR33 ENSG00000214943 "G protein-coupled receptor 33" Q49SQ1 14 31482875-31488039 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "cDC: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "myeloid DC: 2.6" "Lineage enhanced" "Detected in single" "dendritic cells: 2.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 55: Lymphoma - Immune response" "Cluster 82: Dendritic cells - Antigen presentation" GPR34 ENSG00000171659 "G protein-coupled receptor 34" Q9UPC5 X 41688973-41697275 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 40.1" "Group enriched" "Detected in many" 6 "Hofbauer cells: 516.9;Kupffer cells: 270.6;Macrophages: 185.7;Microglia: 282.9" "Cell type enriched" "Detected in all" 49 "central nervous system macrophage: 332.2" "Group enriched" "Detected in all" 4 "Glioblastoma Multiforme (TCGA): 41.4;Kidney Renal Clear Cell Carcinoma (TCGA): 14.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "basophil: 326.2;eosinophil: 113.2" "Lineage enriched" "Detected in many" 24 "granulocytes: 326.2" "Cancer enhanced" "Detected in single" "lymphoma: 1.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Spleen - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010668, CAB025490" Uncertain Approved Cytosol NA NA "Cluster 41: Basophils - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 1 Cytosol "CAB025490: , HPA010668: " "unprognostic (5.57e-2)" "unprognostic (2.70e-2)" "unprognostic (1.94e-1)" "unprognostic (1.15e-1)" "unprognostic (3.02e-1)" "unprognostic (7.16e-3)" "unprognostic (1.75e-1)" "unprognostic (3.42e-1)" "unprognostic (5.88e-2)" "unprognostic (2.03e-1)" "potential prognostic favorable (7.07e-5)" "unprognostic (5.82e-2)" "unprognostic (3.91e-2)" "unprognostic (1.78e-3)" "unprognostic (9.60e-2)" "unprognostic (1.04e-3)" "unprognostic (5.48e-2)" "unprognostic (2.99e-2)" "unprognostic (1.39e-3)" "unprognostic (1.34e-2)" "potential prognostic unfavorable (9.77e-4)" "unprognostic (6.87e-2)" "unprognostic (2.01e-1)" "unprognostic (2.95e-1)" "unprognostic (5.73e-2)" "unprognostic (7.09e-2)" "unprognostic (7.60e-2)" "potential prognostic unfavorable (7.05e-4)" "unprognostic (2.96e-1)" "unprognostic (5.63e-3)" "unprognostic (2.06e-1)" GPR35 ENSG00000178623 "G protein-coupled receptor 35" Q9HC97 2 240605430-240633159 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 44.3" "Cell type enhanced" "Detected in many" "Colonocytes: 88.9;Enteric stem cells: 38.1;Enteric transient amplifying cells: 41.3;Enterocytes: 124.5;Foveolar cells: 47.5;Gastric progenitor cells: 26.9;Goblet cells: 42.2;monocytes: 30.0;Mucous neck cells: 34.9;Tuft cells: 57.6" "Cell type enhanced" "Detected in many" "endothelial cell: 11.6" "Group enriched" "Detected in many" 5 "Colon Adenocarcinoma (TCGA): 68.6;Pancreatic Adenocarcinoma (TCGA): 28.6;Rectum Adenocarcinoma (TCGA): 70.2;Stomach Adenocarcinoma (TCGA): 37.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 14 "classical monocyte: 31.0;eosinophil: 32.6;intermediate monocyte: 44.7;myeloid DC: 27.6;non-classical monocyte: 12.3" "Group enriched" "Detected in many" 16 "dendritic cells: 27.6;granulocytes: 32.6;monocytes: 44.7" "Cancer enhanced" "Detected in many" "Bile duct cancer: 32.8;colorectal cancer: 59.8;Gastric cancer: 38.3" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 67 "unprognostic (2.39e-1)" "unprognostic (1.47e-1)" "unprognostic (3.45e-2)" "unprognostic (1.43e-1)" "unprognostic (1.67e-2)" "unprognostic (1.90e-3)" "unprognostic (1.38e-2)" "unprognostic (1.51e-3)" "unprognostic (5.29e-3)" "unprognostic (1.41e-2)" "unprognostic (2.53e-1)" "unprognostic (3.76e-2)" "unprognostic (1.89e-2)" "unprognostic (2.67e-2)" "unprognostic (5.23e-3)" "unprognostic (3.08e-1)" "unprognostic (6.83e-2)" "unprognostic (8.95e-2)" "unprognostic (1.80e-1)" "unprognostic (2.61e-2)" "unprognostic (7.92e-2)" "unprognostic (1.26e-1)" "unprognostic (8.46e-3)" "unprognostic (2.94e-1)" "unprognostic (7.34e-2)" "unprognostic (2.46e-2)" "unprognostic (1.45e-1)" "unprognostic (1.36e-2)" "unprognostic (9.13e-3)" GPR37 "EDNRBL, hET(B)R-LP, PAELR" ENSG00000170775 "G protein-coupled receptor 37" O15354 7 124743885-124765792 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 67.2;retina: 36.2" "Group enriched" "Detected in many" 7 "Müller glia: 787.4;Oligodendrocytes: 380.2" "Cell type enriched" "Detected in all" 4 "oligodendrocyte: 466.1" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 17.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 7.4" "Colon - Colon enteroendocrine cells, Liver - Hepatocytes, Skin - Inner root sheath cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042903, HPA068009" Approved Uncertain "Nuclear membrane,Nucleoli,Cytosol" No No 2700000 "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 7: Liver cancer - Metabolism" "Cluster 11: Muller glia cells - Retinal homeostasis" 41 "Nuclear membrane" "Nucleoli, Cytosol" "HPA042903: , HPA068009: " "unprognostic (6.59e-2)" "unprognostic (1.88e-1)" "unprognostic (1.00e-1)" "unprognostic (2.82e-1)" "unprognostic (6.79e-2)" "unprognostic (2.22e-2)" "unprognostic (5.68e-2)" "unprognostic (2.43e-1)" "unprognostic (6.88e-2)" "unprognostic (3.51e-1)" "unprognostic (9.41e-2)" "unprognostic (2.38e-1)" "unprognostic (2.40e-2)" "validated prognostic unfavorable (8.72e-5)" "validated prognostic unfavorable (9.13e-4)" "unprognostic (1.68e-2)" "unprognostic (1.33e-2)" "unprognostic (1.11e-3)" "unprognostic (6.61e-3)" "potential prognostic unfavorable (8.70e-4)" "unprognostic (1.49e-1)" "unprognostic (5.55e-2)" "unprognostic (1.05e-1)" "unprognostic (4.15e-2)" GPR37L1 ETBR-LP-2 ENSG00000170075 "G protein-coupled receptor 37 like 1" O60883 1 202122886-202133592 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "brain: 44.8" "Cell type enhanced" "Detected in some" "Astrocytes: 153.1;Bergmann glia: 209.8;Ependymal cells: 63.4;Epicardial cells: 25.0;Müller glia: 59.5;Oligodendrocyte progenitor cells: 186.5;Oligodendrocytes: 42.0;Schwann cells: 23.4" "Cell type enhanced" "Detected in many" "astrocyte: 161.2;Bergmann glia: 238.4;oligodendrocyte precursor cell: 211.6" "Cancer enriched" "Detected in some" 45 "Glioblastoma Multiforme (TCGA): 55.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA061629, HPA064454" Enhanced Approved "Nucleoplasm,Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 49 "Nucleoplasm, Cell Junctions" "Vesicles, Plasma membrane" "HPA061629: , HPA064454: " "unprognostic (3.14e-2)" "unprognostic (7.16e-2)" "unprognostic (1.55e-1)" "unprognostic (8.65e-3)" "unprognostic (2.14e-1)" "unprognostic (8.24e-2)" "unprognostic (6.30e-2)" GPR39 ENSG00000183840 "G protein-coupled receptor 39" O43194 2 132416805-132646582 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 6.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 300.1;Colonocytes: 104.3;Distal convoluted tubule cells: 133.0;Ependymal cells: 126.8;Papillary tip epithelial cells: 113.3;Renal collecting duct principal cells: 129.5;Renal connecting tubule cells: 125.8;Transitional alveolar cells: 253.0" "Cell type enhanced" "Detected in many" "ependymal cell: 155.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "plasmacytoid DC: 1.3" "Lineage enriched" "Detected in single" 14 "dendritic cells: 1.3" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA022111 Approved NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 46: Brainstem - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 51: Secretory epithelial cells - Mixed function" 1 "HPA022111: " "unprognostic (4.33e-2)" "unprognostic (3.01e-2)" "unprognostic (2.87e-1)" "unprognostic (2.52e-2)" "unprognostic (7.75e-2)" "unprognostic (7.49e-3)" "unprognostic (2.24e-2)" "unprognostic (7.28e-2)" "unprognostic (8.23e-2)" "unprognostic (6.39e-2)" "unprognostic (2.19e-2)" "unprognostic (6.81e-2)" "unprognostic (4.24e-2)" "unprognostic (1.01e-2)" "unprognostic (1.33e-1)" "unprognostic (5.00e-2)" "unprognostic (6.82e-2)" "potential prognostic unfavorable (2.86e-4)" "unprognostic (1.97e-1)" "unprognostic (3.09e-1)" "unprognostic (5.52e-2)" "unprognostic (1.17e-3)" "unprognostic (4.05e-3)" "unprognostic (1.63e-2)" "unprognostic (1.68e-1)" "unprognostic (4.87e-2)" "unprognostic (4.12e-1)" "unprognostic (1.90e-1)" "unprognostic (1.88e-1)" "unprognostic (1.32e-1)" GPR4 ENSG00000177464 "G protein-coupled receptor 4" P46093 19 45589764-45602212 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 38.2" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 27.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "ovarian cancer: 1.8;prostate cancer: 2.2;Rhabdoid: 3.3;Sarcoma: 4.3;thyroid cancer: 4.1" "Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Pituitary gland - Endothelial cells, Prostate - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014278 Uncertain NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 1 "HPA014278: " "unprognostic (1.28e-1)" "unprognostic (1.46e-2)" "unprognostic (1.46e-1)" "potential prognostic unfavorable (2.77e-4)" "unprognostic (6.00e-2)" "unprognostic (6.10e-2)" "unprognostic (2.36e-1)" "unprognostic (3.50e-2)" "unprognostic (1.08e-1)" "unprognostic (2.67e-1)" "validated prognostic favorable (7.25e-5)" "validated prognostic favorable (8.36e-6)" "potential prognostic unfavorable (1.12e-6)" "unprognostic (1.25e-1)" "unprognostic (5.18e-3)" "unprognostic (1.36e-3)" "potential prognostic unfavorable (7.24e-4)" "unprognostic (1.32e-2)" "unprognostic (2.79e-1)" "unprognostic (1.14e-1)" "unprognostic (1.93e-1)" "unprognostic (1.02e-1)" "unprognostic (9.12e-2)" "unprognostic (7.32e-2)" "unprognostic (8.04e-3)" "unprognostic (1.06e-2)" "unprognostic (3.44e-2)" "unprognostic (2.30e-3)" "unprognostic (1.28e-1)" "unprognostic (5.42e-2)" "unprognostic (6.66e-3)" GPR42 "FFAR3L, GPR41L, GPR42P" ENSG00000126251 "G protein-coupled receptor 42" O15529 19 35371068-35372962 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Innate lymphoid cells: 4.8;Macrophages: 1.8;Mast cells: 8.6;monocytes: 3.6;Neuroendocrine cells: 1.4;Neutrophils: 2.5;Pancreatic islet cells: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA044681 Uncertain NA NA "Cluster 58: Mast cells - Allergic inflammatory responses" 88 "HPA044681: " GPR45 "PSP24, PSP24A" ENSG00000135973 "G protein-coupled receptor 45" Q9Y5Y3 2 105241743-105243467 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.0" "Group enriched" "Detected in some" 31 "Early spermatids: 6.4;Late spermatids: 14.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Kidney cancer: 2.0" "Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA055940 Uncertain NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 197 "HPA055940: " "potential prognostic favorable (2.56e-4)" GPR50 "H9, Mel1c" ENSG00000102195 "G protein-coupled receptor 50" Q13585 X 151176584-151181465 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 16 "pituitary gland: 15.6" "Cell type enriched" "Detected in single" 15 "Lactotrophs: 4.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Head and Neck Squamous Cell Carcinoma (TCGA): 2.2;Lung Squamous Cell Carcinoma (TCGA): 2.0;Testicular Germ Cell Tumor (TCGA): 1.8" "Region enhanced" "Detected in many" "hypothalamus: 7.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Neuroblastoma: 23.7" "Group enriched" "Detected in many" 4 "hypothalamus: 14.4;white matter: 5.0" "Region enriched" "Detected in single" 12 "hypothalamus: 6.6" "HPA049862, HPA054678" Enhanced Supported "Nucleoplasm,Plasma membrane,Primary cilium,Primary cilium tip" NA NA "Cluster 20: Pituitary gland - Hormone signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 3 "Plasma membrane" "Nucleoplasm, Primary cilium, Primary cilium tip" "HPA049862: , HPA054678: " "unprognostic (3.88e-2)" "unprognostic (1.18e-2)" "unprognostic (4.59e-2)" "unprognostic (7.53e-2)" GPR52 ENSG00000203737 "G protein-coupled receptor 52" Q9Y2T5 1 174447964-174449545 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 8 "brain: 5.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pituitary gland - Lactotropes" "Region enriched" "Detected in many" 6 "basal ganglia: 103.8" "Region enhanced" "Detected in all" "basal ganglia: 42.0" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 3: Rhabdoid - Membrane components" 4 "unprognostic (1.04e-1)" "unprognostic (1.46e-2)" "unprognostic (1.69e-2)" "unprognostic (2.45e-3)" GPR55 ENSG00000135898 "G protein-coupled receptor 55" Q9Y2T6 2 230907318-230961066 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.5;lymphoid tissue: 4.2;testis: 4.4" "Group enriched" "Detected in some" 4 "Sertoli cells: 56.0;Tuft cells: 46.1" "Cell type enhanced" "Detected in many" "leukocyte: 5.0" "Low cancer specificity" "Detected in single" "Region enriched" "Detected in some" 4 "basal ganglia: 9.6" "Immune cell enhanced" "Detected in some" "naive B-cell: 1.9" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Bile duct cancer: 4.9;lymphoma: 4.7" "Prostate - T-cells, Skin - T-cells, Stomach - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 33: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 9: T-cells - Adaptive immunity: Regulation" 48 "unprognostic (6.58e-3)" "unprognostic (2.18e-1)" "unprognostic (5.60e-3)" "unprognostic (4.82e-2)" "unprognostic (3.10e-1)" GPR6 ENSG00000146360 "G protein-coupled receptor 6" P46095 6 109978256-109980720 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "brain: 34.4" "Group enriched" "Detected in some" 6 "Brain inhibitory neurons: 13.3;Lactotrophs: 4.2;Other brain neurons: 4.4" "Cell type enriched" "Detected in some" 7 "medium spiny neuron: 31.9" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "basal ganglia: 54.5;hypothalamus: 14.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pituitary gland - Lactotropes" "Region enriched" "Detected in many" 11 "basal ganglia: 91.1" "Region enriched" "Detected in many" 4 "basal ganglia: 39.1" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 35: Neurons - Synaptic function & neurogenesis" "unprognostic (2.56e-1)" GPR61 BALGR ENSG00000156097 "G protein-coupled receptor 61" Q9BZJ8 1 109539872-109548406 "Essential proteins, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "pituitary gland: 1.9;retina: 2.3" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 10.6;Brain excitatory neurons: 9.5;Brain inhibitory neurons: 9.4;Cardiomyocytes: 9.6;Corticotrophs: 20.1;Lactotrophs: 12.7;Other brain neurons: 9.8;Retinal bipolar cells: 13.9;Retinal pigment epithelial cells: 38.4;Somatotrophs: 5.7;Thyrotrophs: 6.7" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA007326, HPA026088" Supported NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 34: Non-specific - Mixed function" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 16 "HPA007326: , HPA026088: " "unprognostic (3.90e-3)" GPR62 ENSG00000180929 "G protein-coupled receptor 62" Q9BZJ7 3 51955381-51957499 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 22.8" "Cell type enriched" "Detected in some" 10 "Oligodendrocytes: 28.9" "Group enriched" "Detected in some" 14 "committed oligodendrocyte precursor: 16.9;oligodendrocyte: 34.2" "Cancer enriched" "Detected in single" 4 "Glioblastoma Multiforme (TCGA): 1.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 1: Neuronal - Visual perception" "Cluster 80: Oligodendrocytes - Myelination" "unprognostic (3.03e-2)" "unprognostic (4.58e-2)" "unprognostic (2.45e-1)" GPR63 "PSP24(beta), PSP24B" ENSG00000112218 "G protein-coupled receptor 63" Q9BZJ6 6 96794125-96837477 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 31.5;Brain inhibitory neurons: 47.2;Choroid plexus epithelial cells: 113.4;Early primary spermatocytes: 38.8;Early spermatids: 28.7;Granulosa cells: 67.3;Lactotrophs: 30.5;Late primary spermatocytes: 52.6;Late spermatids: 55.8;Other brain neurons: 23.4" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 148.2" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 10.0" "Pituitary gland - Lactotropes, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039103 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 21: Testis - Mixed function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" "Nucleoplasm, Plasma membrane, Cytosol" "HPA039103: " "unprognostic (2.07e-1)" "unprognostic (2.73e-1)" "unprognostic (6.92e-2)" "unprognostic (1.86e-1)" "unprognostic (1.38e-1)" "unprognostic (2.62e-2)" "unprognostic (1.71e-1)" GPR65 "hTDAG8, TDAG8" ENSG00000140030 "G protein-coupled receptor 65" Q8IYL9 14 88005135-88014811 "G-protein coupled receptors, Predicted membrane proteins" Apoptosis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 11.9;lymphoid tissue: 9.1" "Cell type enhanced" "Detected in some" "cDC: 73.1;Innate lymphoid cells: 134.6;Kupffer cells: 168.1;Macrophages: 63.5;Mast cells: 547.0;monocytes: 70.3;Neutrophils: 241.0;NK-cells: 216.8;pDCs: 113.5;T-cells: 143.4" "Group enriched" "Detected in some" 35 "central nervous system macrophage: 43.3;leukocyte: 99.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Leukemia: 3.6;lymphoma: 7.1" "Adrenal gland - Macrophages, Skeletal muscle - Macrophages, Testis - Early spermatids, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA072624, HPA077397" Enhanced Approved Nucleoli,Vesicles,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 58: Mast cells - Allergic inflammatory responses" 1 Vesicles "Nucleoli, Cytosol" "HPA072624: , HPA077397: " "unprognostic (1.28e-1)" "unprognostic (1.26e-1)" "unprognostic (8.35e-2)" "unprognostic (3.04e-1)" "unprognostic (2.01e-1)" "unprognostic (2.93e-2)" "unprognostic (1.24e-1)" "unprognostic (3.28e-1)" "unprognostic (1.57e-1)" "unprognostic (1.83e-2)" "potential prognostic favorable (8.93e-4)" "unprognostic (2.96e-2)" "unprognostic (8.99e-2)" "unprognostic (4.73e-1)" "unprognostic (2.19e-1)" "unprognostic (8.79e-2)" "unprognostic (1.89e-1)" "unprognostic (2.33e-1)" "unprognostic (5.54e-2)" "unprognostic (1.87e-1)" "unprognostic (8.73e-3)" GPR68 OGR1 ENSG00000119714 "G protein-coupled receptor 68" Q15743 14 91232532-91253925 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Amelogenesis imperfecta, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 11.7" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 28.8;Epicardial cells: 36.4;Hofbauer cells: 47.3;Innate lymphoid cells: 59.7;NK-cells: 26.5;Somatotrophs: 27.7;T-cells: 28.1" "Cell type enhanced" "Detected in many" "leukocyte: 29.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 22.9" "Group enriched" "Detected in many" 9 "NK-cells: 20.2;T-cells: 22.9" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal medulla cells, Pituitary gland - Somatotropes, Skeletal muscle - Fibroblasts, Spleen - T-cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 1: Neurons - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" "unprognostic (1.63e-1)" "unprognostic (3.52e-1)" "unprognostic (2.34e-1)" "unprognostic (2.41e-2)" "unprognostic (2.92e-2)" "unprognostic (8.73e-2)" "unprognostic (7.27e-2)" "unprognostic (2.50e-1)" "unprognostic (5.79e-2)" "potential prognostic unfavorable (5.97e-4)" "unprognostic (9.93e-2)" "unprognostic (2.25e-3)" "unprognostic (4.71e-1)" "unprognostic (1.10e-2)" "unprognostic (4.87e-2)" "unprognostic (7.73e-2)" "unprognostic (3.99e-2)" "unprognostic (1.69e-2)" "unprognostic (4.30e-2)" "unprognostic (8.71e-2)" "unprognostic (3.93e-1)" "unprognostic (7.42e-2)" "unprognostic (1.07e-2)" "unprognostic (6.40e-2)" "unprognostic (4.44e-2)" "unprognostic (2.56e-2)" "unprognostic (5.66e-2)" "unprognostic (1.89e-1)" GPR75 WI-31133 ENSG00000119737 "G protein-coupled receptor 75" O95800 2 53852912-53859967 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 9.8;retina: 7.1" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Glioblastoma Multiforme (TCGA): 7.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056032 Supported "Vesicles,Plasma membrane,Primary cilium" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Plasma membrane" "Vesicles, Primary cilium" "HPA056032: " "unprognostic (1.37e-1)" "unprognostic (4.79e-2)" "unprognostic (2.55e-2)" "unprognostic (5.93e-2)" "unprognostic (4.50e-1)" "unprognostic (7.27e-2)" "unprognostic (1.53e-1)" "unprognostic (8.54e-2)" "unprognostic (1.85e-2)" "unprognostic (2.02e-1)" "unprognostic (2.11e-2)" "unprognostic (1.53e-1)" "unprognostic (8.99e-2)" "unprognostic (2.64e-1)" GPR78 ENSG00000155269 "G protein-coupled receptor 78" Q96P69 4 8558725-8619761 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "cervix: 2.0;esophagus: 6.3;placenta: 2.8;vagina: 1.8" "Group enriched" "Detected in some" 12 "Esophageal apical cells: 186.5;Extravillous trophoblasts: 220.1" "Cell type enhanced" "Detected in some" "deep-layer corticothalamic and 6b: 3.3" "Group enriched" "Detected in some" 5 "Bladder Urothelial Carcinoma (TCGA): 3.9;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "Bladder cancer: 5.1;testis cancer: 2.6" "Skin - Outer root sheath cells" HPA013209 Uncertain NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 51: Neurons - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" "HPA013209: " "unprognostic (4.13e-1)" "unprognostic (1.64e-2)" GPR82 ENSG00000171657 "G protein-coupled receptor 82" Q96P67 X 41724181-41730130 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 2.5;lymphoid tissue: 6.5" "Cell type enhanced" "Detected in many" "Epicardial cells: 29.6;Innate lymphoid cells: 22.6;Kupffer cells: 63.5;Macrophages: 19.6;NK-cells: 13.8;Retinal ganglion cells: 19.3;T-cells: 15.3" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 5.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "eosinophil: 40.1;NK-cell: 10.8" "Group enriched" "Detected in many" 10 "granulocytes: 40.1;NK-cells: 10.8" "Not detected" "Not detected" "Kidney - Macrophages, Liver - Kupffer cells, Pancreas - Macrophages, Prostate - Macrophages, Thyroid gland - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA035914 Approved NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" "HPA035914: " "unprognostic (1.69e-1)" "unprognostic (2.73e-1)" "unprognostic (1.59e-1)" "unprognostic (2.59e-3)" "unprognostic (2.21e-1)" "unprognostic (1.66e-1)" "unprognostic (2.58e-1)" "unprognostic (1.91e-2)" "potential prognostic favorable (3.50e-5)" "unprognostic (4.81e-2)" "unprognostic (7.78e-3)" "unprognostic (1.63e-2)" "unprognostic (1.06e-1)" "unprognostic (6.64e-2)" "unprognostic (1.48e-1)" GPR83 GPR72 ENSG00000123901 "G protein-coupled receptor 83" Q9NYM4 11 94377316-94401419 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "brain: 15.0" "Group enriched" "Detected in some" 5 "Brain excitatory neurons: 6.4;Brain inhibitory neurons: 5.6;Endometrial ciliated cells: 2.9;Other brain neurons: 8.7;Schwann cells: 6.7" "Cell type enhanced" "Detected in many" "MGE interneuron: 24.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adrenal gland - Adrenal medulla cells, Thyroid gland - Thyroid glandular cells" "Region enhanced" "Detected in many" "basal ganglia: 67.5" "Low region specificity" "Detected in many" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 56: Non-specific - Sensory perception" "Cluster 109: Neurons - Neuronal signaling" "unprognostic (2.76e-2)" "unprognostic (5.90e-2)" "unprognostic (3.90e-2)" "unprognostic (1.51e-2)" GPR84 EX33 ENSG00000139572 "G protein-coupled receptor 84" Q9NQS5 12 54362445-54364487 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 21.5;urinary bladder: 14.6" "Group enriched" "Detected in some" 4 "Hofbauer cells: 18.2;Macrophages: 18.6;monocytes: 35.6;Neutrophil progenitors: 43.9;Neutrophils: 70.6" "Cell type enriched" "Detected in single" 12 "central nervous system macrophage: 3.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 23 "basophil: 9.1;classical monocyte: 9.9;myeloid DC: 14.8;neutrophil: 6.0" "Group enriched" "Detected in many" 62 "dendritic cells: 14.8;granulocytes: 9.1;monocytes: 9.9" "Group enriched" "Detected in some" 6 "Leukemia: 3.9;lymphoma: 7.6" "Adipose subcutaneous - Macrophages, Kidney - Macrophages, Lung - Neutrophils_2, Spleen - Neutrophils_2" "Low region specificity" "Detected in many" HPA027603 Enhanced NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 1 "HPA027603: " "unprognostic (1.44e-1)" "unprognostic (5.88e-2)" "unprognostic (8.70e-2)" "unprognostic (3.19e-2)" "unprognostic (3.27e-1)" "unprognostic (2.36e-1)" "unprognostic (5.00e-2)" "unprognostic (6.11e-2)" "unprognostic (1.09e-1)" "potential prognostic unfavorable (5.24e-6)" "unprognostic (1.29e-3)" "unprognostic (2.48e-1)" "unprognostic (2.24e-1)" "unprognostic (7.33e-3)" "unprognostic (5.13e-2)" "unprognostic (6.26e-2)" "unprognostic (3.11e-1)" "unprognostic (3.17e-1)" "unprognostic (2.79e-2)" "unprognostic (5.94e-2)" "unprognostic (3.50e-1)" "unprognostic (7.93e-3)" "unprognostic (1.80e-1)" "unprognostic (4.79e-2)" "unprognostic (1.37e-1)" GPR85 SREB2 ENSG00000164604 "G protein-coupled receptor 85" P60893 7 113078331-113087778 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 19.1;retina: 11.2;skeletal muscle: 29.7" "Cell type enhanced" "Detected in many" "Early spermatids: 187.0;Hofbauer cells: 88.0;Kupffer cells: 55.3;Late primary spermatocytes: 200.7;Retinal amacrine cells: 61.5;Retinal bipolar cells: 60.2;Retinal horizontal cells: 74.1;Vascular endothelial cells: 29.9" "Cell type enriched" "Detected in many" 6 "endothelial cell: 588.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Leukemia: 7.9" "Breast - Endothelial cells, Liver - Kupffer cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 104: Brain endothelial cells - Blood brain barrier" 1 "potential prognostic favorable (5.30e-4)" "unprognostic (4.69e-2)" "unprognostic (2.06e-1)" "unprognostic (1.07e-2)" "unprognostic (7.31e-3)" "unprognostic (9.52e-2)" "unprognostic (1.40e-2)" "unprognostic (2.00e-3)" "unprognostic (9.89e-2)" "unprognostic (3.16e-2)" "unprognostic (3.64e-1)" "unprognostic (2.75e-2)" "unprognostic (1.89e-1)" "unprognostic (1.35e-1)" "unprognostic (2.66e-1)" "unprognostic (2.50e-1)" "unprognostic (1.40e-1)" "unprognostic (2.57e-2)" "unprognostic (1.91e-1)" "unprognostic (1.32e-1)" "unprognostic (4.71e-2)" GPR87 GPR95 ENSG00000138271 "G protein-coupled receptor 87" Q9BY21 3 151294086-151316820 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 42.1;skin 1: 37.4;vagina: 27.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 70.6;Cytotrophoblasts: 67.3;Epididymal basal cells: 378.7;Esophageal apical cells: 295.7;Esophageal basal cells: 74.4;Esophageal suprabasal cells: 139.4;Migrating cytotrophoblasts: 100.0;Ocular epithelial cells: 98.0;Suprabasal keratinocytes: 98.3;Syncytiotrophoblasts: 315.8;Urothelial cells: 127.3" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 9.1" "Group enriched" "Detected in many" 5 "Bladder Urothelial Carcinoma (TCGA): 34.9;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 61.7;Head and Neck Squamous Cell Carcinoma (TCGA): 64.5;Lung Squamous Cell Carcinoma (TCGA): 58.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 70.8;head and neck cancer: 95.6" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA066313 Approved "Nucleoplasm,Lipid droplets,Mitochondria" No No "Cluster 81: Squamous epithelium - Keratinization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" "Lipid droplets, Mitochondria" Nucleoplasm "HPA066313: " "unprognostic (2.42e-1)" "unprognostic (1.54e-1)" "unprognostic (1.86e-1)" "unprognostic (8.63e-2)" "unprognostic (1.04e-2)" "unprognostic (5.06e-2)" "unprognostic (4.29e-3)" "unprognostic (1.37e-2)" "unprognostic (1.98e-2)" "unprognostic (9.04e-2)" "validated prognostic unfavorable (6.81e-6)" "validated prognostic unfavorable (2.69e-4)" "unprognostic (2.27e-1)" "unprognostic (3.21e-1)" "unprognostic (2.83e-3)" GPR88 ENSG00000181656 "G protein-coupled receptor 88" Q9GZN0 1 100538139-100542021 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 73.7" "Group enriched" "Detected in some" 7 "Brain inhibitory neurons: 49.1;Pituicytes/FSCs: 32.3;Retinal amacrine cells: 18.6" "Group enriched" "Detected in many" 5 "eccentric medium spiny neuron: 87.9;medium spiny neuron: 139.3" "Cancer enriched" "Detected in some" 7 "Liver Hepatocellular Carcinoma (TCGA): 14.4" "Region enriched" "Detected in all" 9 "basal ganglia: 200.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Spleen - Fibroblasts_1" "Region enriched" "Detected in many" 10 "basal ganglia: 719.1" "Region enriched" "Detected in many" 42 "basal ganglia: 358.6" HPA007488 Approved NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 35: Neurons - Synaptic function & neurogenesis" 1 "HPA007488: " "unprognostic (2.28e-1)" "unprognostic (2.25e-1)" "unprognostic (1.61e-1)" "unprognostic (1.05e-1)" "unprognostic (1.06e-1)" GPR89A UNQ192 ENSG00000117262 "G protein-coupled receptor 89A" B7ZAQ6 1 145607988-145670650 "Predicted membrane proteins" "Ion transport, Protein transport, Transport" "Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Tuft cells: 172.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Pituitary gland - Somatotropes, Testis - Early spermatids" HPA076096 Approved "Endoplasmic reticulum" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 76: Non-specific - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 95: Tuft cells - Chemosensory signaling" 6 "Endoplasmic reticulum" "HPA076096: " "potential prognostic unfavorable (3.74e-4)" "unprognostic (8.49e-2)" "unprognostic (1.03e-2)" "unprognostic (2.06e-1)" "unprognostic (7.44e-2)" "unprognostic (2.40e-1)" "unprognostic (9.98e-2)" "unprognostic (3.30e-1)" "unprognostic (1.01e-1)" "unprognostic (3.96e-1)" "potential prognostic favorable (5.18e-6)" "unprognostic (8.66e-2)" "unprognostic (4.56e-2)" "unprognostic (1.24e-1)" "unprognostic (1.77e-3)" "unprognostic (2.82e-2)" "unprognostic (5.15e-3)" "unprognostic (1.39e-1)" "unprognostic (4.21e-1)" "unprognostic (2.95e-1)" "unprognostic (1.43e-1)" "unprognostic (1.02e-2)" "unprognostic (2.90e-2)" "unprognostic (2.37e-1)" "unprognostic (2.74e-2)" "unprognostic (9.86e-2)" "unprognostic (1.40e-1)" "unprognostic (1.29e-1)" "unprognostic (2.55e-1)" "unprognostic (1.48e-1)" "unprognostic (1.40e-1)" GPR89B "GPR89, GPR89C, SH120" ENSG00000188092 "G protein-coupled receptor 89B" P0CG08 1 147928393-147993592 "Predicted membrane proteins" "Ion transport, Protein transport, Transport" "Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Tuft cells: 184.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA076096 Approved "Endoplasmic reticulum" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 76: Non-specific - Metabolism" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 2 "Endoplasmic reticulum" "HPA076096: " "unprognostic (3.48e-3)" "unprognostic (3.52e-3)" "unprognostic (1.73e-2)" "potential prognostic favorable (8.45e-4)" "unprognostic (1.05e-1)" "unprognostic (1.86e-2)" "unprognostic (1.27e-1)" "unprognostic (7.54e-3)" "unprognostic (4.05e-2)" "unprognostic (5.91e-2)" "potential prognostic favorable (5.72e-5)" "unprognostic (9.16e-2)" "unprognostic (2.05e-1)" "potential prognostic unfavorable (2.34e-4)" "unprognostic (2.36e-1)" "unprognostic (7.15e-2)" "unprognostic (1.68e-2)" "unprognostic (9.39e-2)" "unprognostic (2.37e-1)" "potential prognostic favorable (2.88e-4)" "unprognostic (5.44e-1)" "unprognostic (1.62e-1)" "unprognostic (3.18e-2)" "unprognostic (1.09e-1)" "unprognostic (1.59e-1)" "unprognostic (1.23e-1)" "unprognostic (9.39e-2)" "unprognostic (3.21e-2)" "unprognostic (2.71e-1)" "unprognostic (1.86e-2)" "unprognostic (1.36e-1)" GPRASP1 "GASP, GASP1" ENSG00000198932 "G protein-coupled receptor associated sorting protein 1" Q5JY77 X 102651092-102659083 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 65.9" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 13.8;Epididymal clear cells: 4.1;Loop of henle epithelial cells: 8.1;Medullary thymic epithelial cells: 4.8;Papillary tip epithelial cells: 4.4;Podocytes: 12.4;Proximal tubule cells: 11.1;Renal collecting duct intercalated cells: 13.0;Renal collecting duct principal cells: 9.9;Renal connecting tubule cells: 21.5" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 11.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Neuroblastoma: 8.2" "Adipose subcutaneous - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000161, HPA031061" Approved Supported Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 65: Brain - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 105: Non-specific - Mixed function" 7 Cytosol "HPA000161: , HPA031061: " "potential prognostic favorable (9.79e-4)" "unprognostic (1.02e-3)" "unprognostic (3.18e-2)" "potential prognostic unfavorable (4.97e-4)" "unprognostic (2.89e-1)" "unprognostic (2.13e-2)" "unprognostic (1.32e-1)" "unprognostic (5.19e-2)" "unprognostic (1.72e-3)" "unprognostic (3.25e-3)" "unprognostic (3.73e-2)" "unprognostic (2.62e-2)" "unprognostic (1.42e-2)" "unprognostic (4.50e-2)" "unprognostic (6.47e-2)" "unprognostic (3.19e-1)" "unprognostic (2.21e-1)" "potential prognostic favorable (3.81e-5)" "unprognostic (1.52e-1)" "unprognostic (1.57e-1)" "unprognostic (7.51e-2)" "unprognostic (9.39e-3)" "unprognostic (2.93e-1)" "unprognostic (2.12e-2)" "unprognostic (2.50e-1)" "potential prognostic unfavorable (9.07e-4)" "unprognostic (8.61e-2)" GPRASP2 "FLJ37327, GASP2" ENSG00000158301 "G protein-coupled receptor associated sorting protein 2" Q96D09 X 102712445-102717733 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Brain excitatory neurons: 21.4;Brain inhibitory neurons: 26.6;Oligodendrocyte progenitor cells: 11.2;Other brain neurons: 42.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD4 T-cell: 1.6" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017438 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 65: Brain - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 98: Neurons - Neurotransmission & signaling" 33 Cytosol Nucleoplasm "HPA017438: " "unprognostic (6.28e-2)" "unprognostic (9.02e-3)" "unprognostic (3.17e-1)" "unprognostic (1.06e-1)" "unprognostic (6.13e-2)" "unprognostic (1.75e-2)" "unprognostic (9.42e-2)" "unprognostic (8.41e-3)" "unprognostic (6.86e-2)" "unprognostic (1.99e-2)" "validated prognostic favorable (5.45e-7)" "validated prognostic favorable (1.05e-4)" "unprognostic (2.59e-1)" "unprognostic (1.66e-1)" "unprognostic (4.08e-1)" "unprognostic (8.32e-2)" "unprognostic (2.04e-2)" "unprognostic (1.63e-1)" "unprognostic (3.07e-2)" "unprognostic (2.35e-2)" "unprognostic (5.07e-2)" "unprognostic (1.15e-3)" "unprognostic (2.04e-1)" "unprognostic (1.69e-1)" "unprognostic (1.02e-1)" "unprognostic (1.60e-1)" "unprognostic (3.87e-1)" "unprognostic (4.67e-2)" "unprognostic (9.97e-2)" "unprognostic (7.13e-2)" "unprognostic (2.12e-1)" GPRASP3 "BHLHB9, GASP3, KIAA1701, p60TRP" ENSG00000198908 "G protein-coupled receptor associated sorting protein family member 3" Q6PI77 X 102720688-102753540 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 19.8;Bergmann glia: 21.2;Brain excitatory neurons: 33.3;Brain inhibitory neurons: 30.1;Choroid plexus epithelial cells: 28.8;Distal convoluted tubule cells: 18.7;Ependymal cells: 17.7;Loop of henle epithelial cells: 13.1;Oligodendrocyte progenitor cells: 29.5;Oligodendrocytes: 26.8;Other brain neurons: 33.9;Papillary tip epithelial cells: 11.3;Podocytes: 20.1;Proximal tubule cells: 16.2;Renal collecting duct principal cells: 10.9;Renal connecting tubule cells: 16.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 1.7" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" HPA000887 Supported Nucleoplasm,Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 65: Brain - Transcription" "Cluster 24: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 102: Non-specific - Mixed function" 51 Cytosol Nucleoplasm "HPA000887: " "unprognostic (1.93e-1)" "unprognostic (4.44e-3)" "unprognostic (2.54e-1)" "unprognostic (2.84e-1)" "unprognostic (8.13e-3)" "unprognostic (1.09e-1)" "unprognostic (1.10e-3)" "unprognostic (1.58e-1)" "unprognostic (2.17e-1)" "potential prognostic unfavorable (3.44e-4)" "potential prognostic favorable (1.36e-5)" "unprognostic (9.26e-3)" "unprognostic (6.89e-3)" "unprognostic (3.00e-1)" "unprognostic (2.87e-3)" "unprognostic (1.82e-1)" "unprognostic (7.99e-2)" "unprognostic (5.20e-2)" "unprognostic (8.36e-2)" "unprognostic (4.13e-2)" "unprognostic (2.47e-2)" "unprognostic (1.90e-1)" "potential prognostic unfavorable (5.25e-4)" "unprognostic (8.81e-2)" "unprognostic (9.01e-2)" "unprognostic (9.74e-2)" "unprognostic (1.02e-1)" "unprognostic (1.15e-1)" "unprognostic (1.41e-1)" "unprognostic (2.64e-2)" GPRC5A "PEIG-1, RAI3, RAIG1, TIG1" ENSG00000013588 "G protein-coupled receptor class C group 5 member A" Q8NFJ5 12 12891559-12917937 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 190.3;urinary bladder: 121.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 3635.1;Alveolar cells type 2: 899.5;Colonocytes: 729.4;Conjunctival goblet cells: 732.0;Esophageal apical cells: 664.7;Ocular epithelial cells: 1154.7;Prostatic club cells: 847.4;Prostatic hillock cells: 802.3;Respiratory basal cells: 1158.2;Respiratory deuterosomal cells: 682.1;Respiratory secretory cells: 987.1;Transitional alveolar cells: 2174.5;Urothelial cells: 2164.8" "Cell type enhanced" "Detected in some" "endothelial cell: 18.0;fibroblast: 11.7;vascular associated smooth muscle cell: 53.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "basophil: 3.6" "Lineage enriched" "Detected in single" 13 "granulocytes: 3.6" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 1, Prostate - Urothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA007928, HPA046526" Enhanced Supported "Vesicles,Plasma membrane,Primary cilium,Primary cilium tip" NA Yes "Cluster 13: Lung - Secretion" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 69: Urothelial cells - Basic cellular functions" 6 Vesicles "Plasma membrane, Primary cilium, Primary cilium tip" "HPA007928: , HPA046526: " "unprognostic (6.04e-3)" "unprognostic (4.75e-3)" "unprognostic (2.45e-2)" "unprognostic (1.77e-2)" "unprognostic (7.09e-2)" "unprognostic (4.25e-2)" "unprognostic (7.05e-3)" "unprognostic (9.99e-2)" "unprognostic (2.45e-1)" "unprognostic (3.42e-2)" "potential prognostic unfavorable (8.40e-10)" "unprognostic (1.65e-3)" "potential prognostic unfavorable (1.57e-5)" "unprognostic (1.68e-1)" "unprognostic (1.67e-2)" "unprognostic (1.50e-1)" "potential prognostic unfavorable (3.60e-4)" "unprognostic (1.04e-1)" "unprognostic (5.34e-3)" "unprognostic (1.64e-1)" "potential prognostic unfavorable (9.31e-5)" "unprognostic (1.17e-1)" "unprognostic (3.55e-1)" "unprognostic (1.96e-1)" "unprognostic (4.85e-3)" "unprognostic (2.15e-1)" "unprognostic (1.60e-1)" "unprognostic (2.03e-1)" "unprognostic (3.21e-1)" "unprognostic (9.15e-2)" GPRC5B RAIG-2 ENSG00000167191 "G protein-coupled receptor class C group 5 member B" Q9NZH0 16 19856691-19886167 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 213.2" "Cell type enhanced" "Detected in many" "Astrocytes: 258.2;Bergmann glia: 309.0;Breast lactating cells: 137.6;Early spermatids: 267.7;Late spermatids: 325.9;Oligodendrocyte progenitor cells: 137.8;Oligodendrocytes: 388.7" "Cell type enhanced" "Detected in all" "astrocyte: 303.5;Bergmann glia: 350.8;oligodendrocyte: 434.0" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 138.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD4 T-cell: 2.8" "Lineage enhanced" "Detected in single" "T-cells: 2.8" "Low cancer specificity" "Detected in many" "Colon - Endothelial cells, Pancreas - Ductal cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015247 Enhanced Supported Nucleoplasm,Nucleoli,Vesicles NA NA 24000 "Cluster 33: Non-specific - ATP binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 28: Astrocytes - Homeostasis & neuron support" 38 Vesicles "Nucleoplasm, Nucleoli" "HPA015247: " "unprognostic (1.89e-1)" "unprognostic (4.01e-2)" "potential prognostic favorable (8.30e-4)" "unprognostic (9.84e-2)" "unprognostic (3.65e-3)" "unprognostic (5.37e-2)" "unprognostic (3.41e-1)" "unprognostic (4.76e-3)" "unprognostic (2.84e-1)" "unprognostic (1.96e-1)" "validated prognostic favorable (5.32e-6)" "validated prognostic favorable (8.25e-4)" "unprognostic (3.44e-3)" "unprognostic (3.30e-2)" "unprognostic (7.45e-2)" "unprognostic (4.76e-2)" "unprognostic (3.27e-2)" "unprognostic (1.75e-1)" "unprognostic (7.32e-2)" "unprognostic (2.11e-1)" "unprognostic (1.02e-1)" "unprognostic (1.17e-1)" "unprognostic (1.25e-2)" "unprognostic (8.10e-2)" "unprognostic (2.72e-1)" "unprognostic (3.26e-1)" "unprognostic (1.44e-1)" "unprognostic (2.62e-2)" "unprognostic (2.51e-1)" "unprognostic (3.92e-2)" "unprognostic (4.40e-2)" GPRC5C RAIG-3 ENSG00000170412 "G protein-coupled receptor class C group 5 member C" Q9NQ84 17 74424851-74451653 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 162.9;stomach 1: 180.1" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 227.2;Endometrial secretory cells: 190.9;Fallopian secretory cells: 151.7;Gastric chief cells: 217.3;Hepatocytes: 206.5;Parietal cells: 222.8;Salivary duct cells: 157.4" "Group enriched" "Detected in many" 5 "pericyte: 153.3;upper rhombic lip: 49.1;vascular associated smooth muscle cell: 160.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 7.9" "Group enriched" "Detected in many" 9 "dendritic cells: 7.9;monocytes: 3.8" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Region enriched" "Detected in all" 9 "cerebellum: 42.5" "Low region specificity" "Detected in all" HPA029776 Enhanced Supported "Nucleoplasm,Vesicles,Plasma membrane,Primary cilium,Primary cilium transition zone" NA Yes 98000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 70: Non-specific - Protein processing" "Cluster 25: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 103: Non-specific - Basic cellular processes" 5 "Vesicles, Plasma membrane" "Nucleoplasm, Primary cilium, Primary cilium transition zone" "HPA029776: " "unprognostic (4.47e-2)" "unprognostic (3.00e-2)" "unprognostic (1.54e-1)" "unprognostic (3.14e-1)" "unprognostic (1.53e-1)" "unprognostic (3.51e-1)" "unprognostic (1.86e-2)" "unprognostic (8.47e-3)" "unprognostic (2.85e-2)" "unprognostic (2.59e-2)" "validated prognostic favorable (6.79e-6)" "validated prognostic favorable (7.97e-5)" "unprognostic (5.85e-3)" "unprognostic (2.66e-3)" "unprognostic (7.99e-2)" "unprognostic (1.22e-2)" "unprognostic (1.74e-2)" "unprognostic (1.21e-2)" "unprognostic (2.13e-1)" "unprognostic (1.44e-3)" "unprognostic (4.26e-1)" "unprognostic (4.36e-2)" "unprognostic (5.43e-1)" "unprognostic (6.09e-2)" "unprognostic (6.39e-2)" "unprognostic (1.24e-1)" "unprognostic (4.88e-2)" "unprognostic (1.89e-2)" "unprognostic (3.83e-2)" "unprognostic (2.45e-1)" "unprognostic (1.85e-1)" GPRC5D ENSG00000111291 "G protein-coupled receptor class C group 5 member D" Q9NZD1 12 12940575-12952170 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "skin 1: 26.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 10.2;Early spermatids: 10.0;Endometrial luminal cells: 23.8;Epicardial cells: 100.1;Esophageal apical cells: 12.0;Late spermatids: 25.9;Plasma cells: 37.8;Urothelial cells: 10.4" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 1.7;choroid plexus epithelial cell: 2.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 10 "memory B-cell: 14.7;naive B-cell: 4.9" "Lineage enriched" "Detected in single" 15 "B-cells: 14.7" "Cancer enriched" "Detected in many" 20 "Myeloma: 60.8" "Breast - Plasma cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA071909 Approved NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 9: Skin - Hair follicle development" "Cluster 44: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 103: Non-specific - Basic cellular processes" 24 "HPA071909: " "unprognostic (2.05e-1)" "unprognostic (3.19e-2)" "unprognostic (3.15e-2)" "unprognostic (7.35e-2)" "unprognostic (4.23e-2)" "unprognostic (6.82e-2)" "unprognostic (1.37e-3)" "potential prognostic unfavorable (2.23e-5)" "unprognostic (7.44e-2)" "unprognostic (2.26e-1)" "unprognostic (5.47e-3)" "unprognostic (2.09e-1)" "unprognostic (1.76e-1)" "unprognostic (3.32e-2)" "unprognostic (3.11e-1)" "unprognostic (2.62e-2)" "unprognostic (9.16e-2)" "unprognostic (1.81e-1)" "unprognostic (1.96e-1)" "unprognostic (2.31e-1)" "unprognostic (1.35e-2)" "unprognostic (2.00e-1)" GPRC6A bA86F4.3 ENSG00000173612 "G protein-coupled receptor class C group 6 member A" Q5T6X5 6 116792085-116829083 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 27 "Salivary ionocytes: 389.4" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 48 "Kidney Chromophobe (TCGA): 11.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Intercalated cells, Minor Salivary Gland - Minor salivary gland ductal cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 20: Myeloma - Immune response" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" "unprognostic (9.74e-2)" GPRIN1 "GRIN1, KIAA1893" ENSG00000169258 "G protein regulated inducer of neurite outgrowth 1" Q7Z2K8 5 176595802-176610156 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 21.2;pituitary gland: 7.6;retina: 6.4" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 12.4;Brain inhibitory neurons: 9.5;Corticotrophs: 12.0;Lactotrophs: 9.0;Other brain neurons: 12.5;Pancreatic islet cells: 11.0;Retinal amacrine cells: 23.4;Retinal bipolar cells: 21.2;Retinal horizontal cells: 14.0;Rod photoreceptor cells: 6.3;Somatotrophs: 6.6;Thyrotrophs: 10.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Colon - Colon enteroendocrine cells, Kidney - Macrophages, Minor Salivary Gland - Mitotic cells (Minor salivary gland), Pituitary gland - Lactotropes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036478, HPA070892" Enhanced Supported "Vesicles,Plasma membrane" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 3 "Plasma membrane" Vesicles "HPA036478: , HPA070892: " "unprognostic (3.90e-1)" "unprognostic (5.15e-2)" "unprognostic (1.25e-1)" "unprognostic (2.61e-1)" "unprognostic (7.09e-2)" "unprognostic (1.28e-1)" "unprognostic (3.53e-2)" "potential prognostic favorable (7.78e-5)" "unprognostic (2.50e-1)" "unprognostic (1.34e-3)" "unprognostic (3.73e-3)" "unprognostic (1.07e-3)" "validated prognostic unfavorable (9.75e-6)" "validated prognostic unfavorable (7.18e-4)" "potential prognostic unfavorable (1.55e-5)" "unprognostic (3.65e-2)" "unprognostic (1.39e-3)" "unprognostic (2.48e-1)" "unprognostic (1.98e-1)" "unprognostic (1.03e-1)" "unprognostic (1.56e-2)" "unprognostic (3.68e-3)" "unprognostic (3.19e-1)" "unprognostic (6.72e-2)" "unprognostic (1.47e-1)" "unprognostic (1.72e-2)" "unprognostic (8.79e-2)" "unprognostic (4.45e-2)" GPRIN2 "KIAA0514, MGC15171" ENSG00000204175 "G protein regulated inducer of neurite outgrowth 2" O60269 10 46541736-46556658 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 9.1;skin 1: 13.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 50.4;Colonocytes: 20.3;Enterocytes: 18.5;Goblet cells: 47.6;Late spermatids: 29.2;Mucous neck cells: 16.5;Paneth cells: 27.1" "Cell type enhanced" "Detected in many" "deep-layer near-projecting: 6.0;lower rhombic lip: 5.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 6.0;prostate cancer: 8.1" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Liver - Cholangiocytes, Lung - Alveolar cells type 1, Pancreas - Ductal cells, Skin - Keratinocyte (granular), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "HPA038129, HPA070760" Approved Approved "Plasma membrane,Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 2: Non-specific - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 70: Intestinal goblet cells - Mucin production" 7 "Plasma membrane, Microtubules" "Cytokinetic bridge, Mitotic spindle" "HPA038129: , HPA070760: " "unprognostic (4.92e-3)" "unprognostic (3.13e-3)" "unprognostic (9.93e-2)" "unprognostic (1.92e-1)" "unprognostic (1.46e-1)" "unprognostic (1.92e-1)" "potential prognostic favorable (5.44e-4)" "unprognostic (3.39e-2)" "unprognostic (2.69e-1)" "unprognostic (2.39e-3)" "unprognostic (1.23e-3)" "unprognostic (5.31e-2)" "unprognostic (8.80e-2)" "unprognostic (3.84e-1)" "unprognostic (1.08e-1)" "unprognostic (8.58e-2)" "unprognostic (1.36e-3)" "unprognostic (1.42e-2)" "unprognostic (3.75e-1)" "unprognostic (3.20e-1)" "unprognostic (5.04e-3)" "unprognostic (3.74e-2)" "unprognostic (3.64e-1)" "unprognostic (3.48e-2)" "potential prognostic unfavorable (8.29e-4)" GPRIN3 "FLJ42625, GRIN3" ENSG00000185477 "GPRIN family member 3" Q6ZVF9 4 89236383-89307800 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.9" "Cell type enhanced" "Detected in many" "cDC: 186.5;Distal convoluted tubule cells: 185.5;Lactotrophs: 181.3;Macrophages: 207.2;Microglia: 207.8;NK-cells: 263.8;Renal collecting duct intercalated cells: 183.4;Somatotrophs: 225.1;T-cells: 337.7;Thyrotrophs: 218.6" "Cell type enhanced" "Detected in all" "leukocyte: 351.6" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 13.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in many" 7 "Myeloma: 28.5" "Adipose visceral - T-cells, Prostate - T-cells, Skeletal muscle - Endothelial cells" "Region enhanced" "Detected in many" "basal ganglia: 16.3" "HPA043148, HPA057666, HPA059092" Enhanced Approved Nucleoplasm,Nucleoli No NA "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 9: T-cells - Adaptive immunity: Regulation" 2 Nucleoli Nucleoplasm "HPA043148: , HPA057666: , HPA059092: " "unprognostic (1.78e-1)" "unprognostic (4.09e-2)" "unprognostic (2.89e-1)" "unprognostic (2.24e-2)" "unprognostic (2.66e-2)" "unprognostic (4.98e-2)" "unprognostic (3.50e-1)" "unprognostic (3.76e-1)" "potential prognostic favorable (9.91e-6)" "unprognostic (2.01e-2)" "unprognostic (4.96e-1)" "unprognostic (1.59e-1)" "unprognostic (4.14e-2)" "unprognostic (7.09e-2)" "unprognostic (5.24e-2)" "unprognostic (1.42e-2)" "unprognostic (4.08e-3)" "unprognostic (9.43e-2)" "unprognostic (6.28e-2)" "unprognostic (2.84e-1)" "unprognostic (2.77e-2)" "unprognostic (1.08e-1)" "unprognostic (1.92e-1)" "unprognostic (1.50e-1)" GPS1 "COPS1, CSN1" ENSG00000169727 "G protein pathway suppressor 1" Q13098 17 82050691-82057470 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 137.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047448, HPA052848" Enhanced Nucleoplasm,Cytosol NA NA 72000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 24: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 66 Nucleoplasm Cytosol "HPA047448: , HPA052848: " "unprognostic (2.13e-1)" "unprognostic (1.00e-1)" "unprognostic (2.63e-1)" "unprognostic (6.41e-2)" "unprognostic (4.32e-2)" "unprognostic (2.92e-2)" "unprognostic (2.41e-1)" "unprognostic (8.76e-2)" "unprognostic (1.26e-2)" "unprognostic (1.24e-2)" "unprognostic (2.32e-2)" "unprognostic (6.68e-2)" "unprognostic (4.39e-2)" "potential prognostic unfavorable (4.28e-7)" "unprognostic (9.98e-3)" "unprognostic (2.48e-2)" "unprognostic (3.84e-2)" "unprognostic (7.92e-2)" "unprognostic (3.13e-2)" "unprognostic (2.55e-2)" "unprognostic (2.15e-2)" "unprognostic (4.01e-2)" "unprognostic (4.50e-1)" "unprognostic (2.93e-1)" "unprognostic (2.88e-1)" "unprognostic (2.09e-2)" "unprognostic (1.90e-1)" "unprognostic (1.36e-1)" "unprognostic (1.96e-1)" "unprognostic (1.50e-2)" "unprognostic (1.24e-2)" GPS2 ENSG00000132522 "G protein pathway suppressor 2" Q13227 17 7311324-7315564 "Cancer-related genes, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Activator, Repressor" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 35.7;Bergmann glia: 41.6;Brain excitatory neurons: 40.4;Brain inhibitory neurons: 33.9;Choroid plexus epithelial cells: 17.3;Ependymal cells: 23.3;Late spermatids: 22.6;Microglia: 38.6;Oligodendrocyte progenitor cells: 30.5;Oligodendrocytes: 42.9;Other brain neurons: 33.8;Papillary tip epithelial cells: 19.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067540 Approved Supported Nucleoplasm NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 42: Non-specific - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" 70 Nucleoplasm "HPA067540: " "unprognostic (1.82e-1)" "unprognostic (2.87e-1)" "unprognostic (1.19e-2)" "unprognostic (1.36e-2)" "unprognostic (1.14e-1)" "unprognostic (4.67e-2)" "unprognostic (1.74e-2)" "unprognostic (2.08e-2)" "unprognostic (2.29e-2)" "unprognostic (6.77e-2)" "unprognostic (1.11e-1)" "unprognostic (2.35e-1)" "unprognostic (6.92e-3)" "unprognostic (8.52e-3)" "unprognostic (1.82e-1)" "unprognostic (6.91e-3)" "unprognostic (8.24e-2)" "unprognostic (1.48e-2)" "unprognostic (1.26e-1)" "unprognostic (1.52e-1)" "unprognostic (1.40e-1)" "unprognostic (2.45e-3)" "unprognostic (8.55e-2)" "unprognostic (1.26e-1)" "unprognostic (1.35e-1)" "unprognostic (1.52e-1)" "unprognostic (2.56e-1)" "unprognostic (7.59e-2)" "unprognostic (1.20e-1)" "unprognostic (2.32e-1)" "unprognostic (3.51e-1)" GPSM1 "AGS3, DKFZP727I051" ENSG00000160360 "G protein signaling modulator 1" Q86YR5 9 136327476-136359605 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 105.6" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 45.1;Müller glia: 38.0;Podocytes: 132.9;Retinal bipolar cells: 36.0;Retinal pigment epithelial cells: 46.9;Rod photoreceptor cells: 73.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Lung - Fibroblasts_1, Prostate - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042199, HPA060736" Approved Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 35: RS4;11 - Unknown function" "Cluster 57: Podocytes - Glomerular filtration" 10 "Golgi apparatus" Nucleoplasm "HPA042199: , HPA060736: " "unprognostic (1.54e-1)" "unprognostic (1.66e-1)" "unprognostic (1.64e-1)" "unprognostic (3.47e-1)" "unprognostic (2.49e-3)" "unprognostic (2.28e-1)" "unprognostic (2.38e-1)" "unprognostic (2.59e-3)" "unprognostic (7.76e-2)" "unprognostic (2.76e-1)" "potential prognostic unfavorable (4.78e-7)" "unprognostic (7.82e-3)" "unprognostic (9.35e-2)" "unprognostic (7.29e-2)" "unprognostic (4.46e-1)" "unprognostic (1.08e-1)" "unprognostic (2.75e-2)" "unprognostic (9.32e-2)" "unprognostic (5.25e-2)" "unprognostic (1.56e-1)" "unprognostic (2.15e-1)" "unprognostic (1.87e-2)" "potential prognostic unfavorable (7.85e-4)" "unprognostic (2.45e-2)" "unprognostic (4.37e-2)" "unprognostic (1.18e-2)" "unprognostic (1.05e-1)" "unprognostic (5.01e-2)" "unprognostic (1.28e-1)" "unprognostic (4.67e-2)" "unprognostic (3.81e-2)" GPSM2 "DFNB82, LGN, Pins" ENSG00000121957 "G protein signaling modulator 2" P81274 1 108875350-108934545 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Mitosis, Transport" Deafness "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 50.8" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 178.0;Esophageal apical cells: 233.7;Fibro-adipogenic progenitors: 217.5;Myosatellite cells: 175.4;Oligodendrocyte progenitor cells: 245.8;Oligodendrocytes: 193.6" "Cell type enhanced" "Detected in all" "oligodendrocyte: 264.3;oligodendrocyte precursor cell: 294.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "eosinophil: 2.8;T-reg: 1.6" "Group enriched" "Detected in many" 8 "granulocytes: 2.8;T-cells: 1.6" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007327, HPA008408, CAB018962" Uncertain Supported Centrosome,Cytosol NA Yes "Cluster 19: Eosinophils - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 15 Cytosol Centrosome "CAB018962: , HPA007327: , HPA008408: " "unprognostic (5.92e-2)" "unprognostic (1.08e-1)" "unprognostic (1.16e-1)" "unprognostic (1.30e-1)" "unprognostic (4.54e-3)" "unprognostic (2.50e-1)" "unprognostic (1.65e-2)" "potential prognostic favorable (1.53e-4)" "unprognostic (5.05e-2)" "unprognostic (6.32e-2)" "validated prognostic unfavorable (6.89e-4)" "validated prognostic unfavorable (6.14e-4)" "unprognostic (1.57e-3)" "validated prognostic unfavorable (1.05e-6)" "validated prognostic unfavorable (6.34e-4)" "unprognostic (2.20e-3)" "unprognostic (2.29e-3)" "unprognostic (7.31e-2)" "unprognostic (4.30e-2)" "unprognostic (7.90e-2)" "unprognostic (4.10e-2)" "potential prognostic unfavorable (6.66e-4)" "unprognostic (5.00e-2)" "unprognostic (2.37e-1)" "unprognostic (2.63e-3)" "unprognostic (1.58e-1)" "unprognostic (7.61e-2)" "unprognostic (6.41e-3)" "unprognostic (5.15e-2)" "unprognostic (1.65e-2)" "unprognostic (2.61e-1)" GPSM3 "AGS4, C6orf9, G18, G18.1a, G18.1b, G18.2, NG1" ENSG00000213654 "G protein signaling modulator 3" Q9Y4H4 6 32190766-32195523 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 151.7;intestine: 65.3;lung: 64.8;lymphoid tissue: 234.9" "Cell type enhanced" "Detected in some" "B-cells: 8.9;Megakaryocytes: 18.5;Microglia: 32.0;monocytes: 6.5;Neutrophils: 16.5;NK-cells: 8.1;Papillary tip epithelial cells: 5.1;Platelets: 14.0;T-cells: 6.3" "Group enriched" "Detected in some" 4 "central nervous system macrophage: 39.6;leukocyte: 116.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 59.2;lymphoma: 49.8" "Adrenal gland - Macrophages, Lung - Neutrophils_2, Skin - T-cells, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 11000 "Cluster 21: Neutrophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 102: Non-specific - Mixed function" 48 "unprognostic (3.84e-1)" "unprognostic (3.59e-2)" "unprognostic (3.22e-1)" "unprognostic (1.08e-1)" "unprognostic (7.33e-3)" "unprognostic (3.78e-3)" "unprognostic (2.00e-1)" "unprognostic (4.55e-1)" "unprognostic (1.95e-2)" "unprognostic (3.45e-2)" "unprognostic (1.37e-2)" "unprognostic (1.80e-1)" "unprognostic (4.65e-2)" "unprognostic (1.98e-1)" "unprognostic (9.80e-2)" "unprognostic (8.61e-3)" "unprognostic (3.60e-2)" "unprognostic (5.39e-2)" "unprognostic (2.21e-1)" "unprognostic (2.03e-1)" "unprognostic (3.96e-1)" "unprognostic (6.65e-2)" "unprognostic (2.17e-2)" "unprognostic (1.27e-1)" "unprognostic (1.63e-1)" "unprognostic (8.84e-2)" "unprognostic (2.59e-2)" "unprognostic (1.01e-1)" "unprognostic (1.18e-2)" "unprognostic (1.38e-1)" "unprognostic (1.91e-1)" GPT "ALT, ALT1, GPT1, SGPT" ENSG00000167701 "Glutamic--pyruvic transaminase" P24298 8 144502973-144507174 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Aminotransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 183.4" "Cell type enhanced" "Detected in many" "Breast lactating cells: 164.1;Colonocytes: 150.3;Enterocytes: 130.5;Foveolar cells: 78.7;Hepatocytes: 250.6;Late spermatids: 95.6;Parietal cells: 46.0;Proximal tubule cells: 45.5" "Group enriched" "Detected in many" 4 "astrocyte: 36.4;Bergmann glia: 21.5;choroid plexus epithelial cell: 14.1" "Cancer enriched" "Detected in many" 6 "Liver Hepatocellular Carcinoma (TCGA): 65.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Colon enterocytes, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Corticotropes, Skeletal muscle - Skeletal myocytes, Stomach - Gastric mucous cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031059, HPA031060, CAB032997, CAB032999" Enhanced NA NA 14000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 48: Non-specific - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 1 "CAB032997: , CAB032999: , HPA031059: , HPA031060: " "unprognostic (2.07e-1)" "unprognostic (1.39e-2)" "unprognostic (1.16e-2)" "unprognostic (2.44e-2)" "unprognostic (7.13e-2)" "unprognostic (1.21e-1)" "unprognostic (4.22e-1)" "unprognostic (1.16e-1)" "unprognostic (1.82e-2)" "unprognostic (2.00e-2)" "potential prognostic favorable (1.26e-5)" "unprognostic (4.05e-2)" "potential prognostic favorable (5.31e-6)" "validated prognostic favorable (2.66e-5)" "validated prognostic favorable (2.94e-4)" "unprognostic (2.39e-2)" "unprognostic (6.73e-2)" "unprognostic (3.33e-1)" "unprognostic (1.36e-1)" "unprognostic (2.10e-1)" "unprognostic (2.13e-1)" "unprognostic (1.99e-1)" "unprognostic (1.15e-1)" "unprognostic (2.73e-2)" "unprognostic (1.79e-2)" "unprognostic (2.17e-1)" "unprognostic (2.01e-1)" GPT2 ALT2 ENSG00000166123 "Glutamic--pyruvic transaminase 2" Q8TD30 16 46884362-46931289 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Aminotransferase, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 252.0;skeletal muscle: 165.4;tongue: 172.2" "Cell type enriched" "Detected in many" 4 "Esophageal apical cells: 761.9" "Cell type enhanced" "Detected in all" "astrocyte: 128.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.3;naive B-cell: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Stomach - Chief cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051514 Approved Approved Mitochondria No No "Cluster 32: Basophils - Transcription" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 84: Apical squamous epithelium - Cornification" 5 Mitochondria "HPA051514: " "unprognostic (6.18e-2)" "unprognostic (1.18e-2)" "unprognostic (4.55e-2)" "unprognostic (1.70e-1)" "unprognostic (2.62e-1)" "unprognostic (1.66e-1)" "unprognostic (1.45e-1)" "unprognostic (3.82e-2)" "unprognostic (4.71e-2)" "unprognostic (2.53e-1)" "unprognostic (2.81e-2)" "unprognostic (1.47e-1)" "unprognostic (1.27e-1)" "potential prognostic favorable (6.39e-4)" "unprognostic (1.06e-3)" "unprognostic (1.30e-1)" "unprognostic (1.67e-1)" "unprognostic (3.48e-1)" "unprognostic (7.43e-3)" "unprognostic (8.84e-3)" "unprognostic (5.08e-1)" "unprognostic (3.00e-2)" "unprognostic (2.64e-1)" "unprognostic (1.53e-1)" "unprognostic (2.49e-2)" "unprognostic (1.95e-1)" "unprognostic (1.91e-1)" "unprognostic (1.39e-1)" "unprognostic (1.64e-1)" "unprognostic (1.35e-3)" "unprognostic (2.66e-2)" GPX1 ENSG00000233276 "Glutathione peroxidase 1" P07203 3 49357174-49358605 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Lipid metabolism" "Oxidoreductase, Peroxidase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial secretory cells: 49.3;Kupffer cells: 59.4;Megakaryocytes: 68.0;Microglia: 235.1;Other brain neurons: 51.6;Platelets: 273.3" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 266.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 1446.8;granulocytes: 913.9;monocytes: 1183.5" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Macrophages, Lung - Macrophages, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011582, HPA044758" Approved Supported Cytosol NA NA 2900000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 20 Cytosol "CAB011582: , HPA044758: " "unprognostic (3.85e-1)" "unprognostic (4.22e-2)" "unprognostic (4.39e-2)" "unprognostic (6.65e-2)" "unprognostic (1.87e-1)" "unprognostic (1.06e-1)" "unprognostic (4.00e-2)" "unprognostic (2.18e-1)" "unprognostic (1.13e-1)" "unprognostic (2.97e-2)" "unprognostic (3.46e-3)" "unprognostic (1.90e-1)" "unprognostic (6.01e-2)" "unprognostic (2.55e-2)" "unprognostic (7.88e-2)" "unprognostic (1.51e-1)" "unprognostic (2.43e-2)" "unprognostic (6.94e-2)" "unprognostic (2.80e-2)" "unprognostic (1.11e-1)" "unprognostic (1.82e-1)" "unprognostic (7.11e-2)" "unprognostic (1.74e-1)" "unprognostic (1.89e-1)" "unprognostic (2.57e-1)" "potential prognostic favorable (2.12e-5)" "unprognostic (1.26e-2)" "unprognostic (2.15e-2)" "unprognostic (1.20e-2)" "unprognostic (2.30e-3)" "unprognostic (5.00e-2)" GPX2 GSHPX-GI ENSG00000176153 "Glutathione peroxidase 2" P18283 14 64939152-64942746 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Oxidoreductase, Peroxidase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 463.7;intestine: 422.0;liver: 616.4;stomach 1: 346.0;urinary bladder: 323.3" "Cell type enhanced" "Detected in many" "Colonocytes: 473.7;Conjunctival goblet cells: 2187.4;Enteric stem cells: 579.0;Enteric transient amplifying cells: 484.5;Esophageal suprabasal cells: 496.6;Foveolar cells: 761.2;Gastric progenitor cells: 566.5;Hepatocytes: 906.8;Paneth cells: 537.6;Prostatic hillock cells: 994.0;Salivary duct cells: 2781.9;Urothelial cells: 1058.2" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in many" "Rectum Adenocarcinoma (TCGA): 1138.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 1245.0" "Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Pituitary gland - Gonadotropes, Prostate - Urothelial cells, Stomach - Gastric mucous cells, Testis - Late spermatids" "Region enriched" "Detected in single" 5 "pons and medulla: 4.1" "Low region specificity" "Detected in many" "HPA003545, HPA075070" Enhanced Supported "Cytokinetic bridge,Mitotic spindle,Cytosol" Yes NA 110000 "Cluster 17: Intestine - Digestion" "Cluster 7: Liver cancer - Metabolism" "Cluster 69: Urothelial cells - Basic cellular functions" 1 Cytosol "Cytokinetic bridge, Mitotic spindle" "HPA003545: , HPA075070: " "potential prognostic favorable (9.37e-4)" "unprognostic (3.25e-1)" "unprognostic (1.34e-1)" "unprognostic (4.13e-2)" "unprognostic (6.32e-2)" "unprognostic (9.56e-3)" "unprognostic (2.18e-3)" "potential prognostic favorable (5.24e-4)" "unprognostic (1.87e-1)" "potential prognostic unfavorable (2.03e-5)" "unprognostic (8.25e-2)" "unprognostic (1.85e-1)" "unprognostic (4.12e-3)" "unprognostic (6.41e-2)" "unprognostic (6.06e-2)" "unprognostic (5.11e-2)" "unprognostic (1.46e-1)" "potential prognostic favorable (1.77e-4)" "unprognostic (9.80e-2)" "unprognostic (3.34e-2)" "unprognostic (1.82e-1)" "unprognostic (2.58e-2)" "unprognostic (4.03e-3)" "unprognostic (5.17e-2)" "unprognostic (6.46e-2)" "unprognostic (7.31e-3)" GPX3 ENSG00000211445 "Glutathione peroxidase 3" P22352 5 151020591-151028988 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 10500.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 636.0;Endometrial glandular cells: 1005.3;Esophageal apical cells: 1926.7;Extravillous trophoblasts: 1685.0;Fibroblasts: 1282.6;Hepatic stellate cells: 1006.9;Migrating cytotrophoblasts: 1456.0;Müller glia: 2922.6;Proximal tubule cells: 1426.1;Syncytiotrophoblasts: 2111.1" "Group enriched" "Detected in many" 4 "choroid plexus epithelial cell: 226.3;vascular associated smooth muscle cell: 58.7" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 2366.6;Thyroid Carcinoma (TCGA): 2628.6" "Group enriched" "Detected in all" 4 "choroid plexus: 1127.5;medulla oblongata: 588.7" "Immune cell enriched" "Detected in some" 5 "neutrophil: 20.8" "Lineage enriched" "Detected in many" 5 "granulocytes: 20.8" "Cancer enhanced" "Detected in all" "ovarian cancer: 198.7;thyroid cancer: 178.6" "Adrenal gland - Fibroblasts, Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Spleen - Fibroblasts_2" "Region enhanced" "Detected in all" "hypothalamus: 239.6" "Low region specificity" "Detected in all" CAB069456 Approved "Secreted to blood" Enzyme NA NA 5090000000 2300000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 72: Kidney - Transmembrane transport" "Cluster 44: Non-specific - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 3 "CAB069456: " "unprognostic (1.54e-1)" "unprognostic (1.40e-1)" "unprognostic (1.51e-3)" "unprognostic (2.70e-3)" "unprognostic (4.45e-2)" "unprognostic (4.92e-2)" "unprognostic (8.94e-3)" "unprognostic (3.35e-1)" "unprognostic (9.25e-2)" "unprognostic (3.33e-1)" "potential prognostic favorable (1.79e-4)" "unprognostic (5.93e-2)" "unprognostic (1.22e-1)" "unprognostic (2.35e-2)" "unprognostic (3.67e-2)" "unprognostic (4.50e-3)" "unprognostic (7.62e-3)" "unprognostic (1.31e-3)" "unprognostic (5.71e-3)" "unprognostic (1.06e-2)" "unprognostic (4.04e-2)" "unprognostic (7.95e-3)" "unprognostic (2.49e-1)" "unprognostic (4.20e-2)" "unprognostic (8.33e-3)" "unprognostic (1.91e-2)" "unprognostic (1.11e-2)" "potential prognostic unfavorable (8.37e-4)" "unprognostic (8.19e-2)" "unprognostic (4.06e-2)" "unprognostic (1.30e-2)" GPX4 "MCSP, PHGPx" ENSG00000167468 "Glutathione peroxidase 4" P36969 19 1103982-1106791 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" "Developmental protein, Oxidoreductase, Peroxidase" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 7 "Late spermatids: 31242.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008630, HPA047224, HPA058546" Enhanced Approved Nucleoplasm,Mitochondria "Intracellular and membrane" "Developmental protein" NA NA 550000 "Cluster 29: Non-specific - Unknown function" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 21: Non-specific - Metabolism" "Cluster 23: Non-specific - Transcription" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 8 "Nucleoplasm, Mitochondria" "CAB008630: , HPA047224: , HPA058546: " "unprognostic (1.41e-1)" "unprognostic (6.00e-2)" "unprognostic (4.81e-1)" "unprognostic (1.91e-2)" "unprognostic (3.37e-3)" "unprognostic (1.87e-1)" "unprognostic (4.44e-2)" "unprognostic (1.06e-1)" "unprognostic (2.34e-1)" "unprognostic (1.27e-1)" "unprognostic (7.21e-3)" "unprognostic (1.63e-1)" "unprognostic (4.82e-2)" "potential prognostic unfavorable (6.09e-4)" "unprognostic (1.23e-2)" "unprognostic (4.01e-2)" "unprognostic (4.36e-2)" "unprognostic (5.69e-2)" "unprognostic (1.81e-1)" "unprognostic (1.29e-1)" "unprognostic (1.63e-1)" "unprognostic (8.88e-2)" "unprognostic (4.74e-2)" "unprognostic (3.77e-2)" "unprognostic (1.66e-1)" "unprognostic (9.18e-3)" "unprognostic (2.22e-2)" "unprognostic (2.40e-3)" "unprognostic (2.01e-1)" "unprognostic (1.44e-2)" "unprognostic (8.84e-2)" GPX5 ENSG00000224586 "Glutathione peroxidase 5" O75715 6 28525881-28534955 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "epididymis: 8.7" "Group enriched" "Detected in some" 5 "Epididymal principal cells: 10.3;Late spermatids: 6.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Secreted in male reproductive system" Enzyme NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" GPX6 GPXP3 ENSG00000198704 "Glutathione peroxidase 6" P59796 6 28503296-28528215 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Oxidoreductase, Peroxidase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 15 "epididymis: 3.1" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 1.5;Early spermatids: 2.0;Epididymal principal cells: 6.7;Late primary spermatocytes: 3.0;Late spermatids: 5.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in some" 16 "basal ganglia: 23.9" "Low region specificity" "Detected in many" "Secreted in male reproductive system" Enzyme NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" GPX7 "FLJ14777, GPX6, NPGPx" ENSG00000116157 "Glutathione peroxidase 7" Q96SL4 1 52602371-52609051 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted secreted proteins" "Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 63.3;Granulosa cells: 34.9;Hepatic stellate cells: 77.5;Megakaryocytes: 55.6;Plasma cells: 39.0" "Cell type enhanced" "Detected in all" "Bergmann glia: 21.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Prostate - Fibroblasts, Skin - Fibroblasts_1, Stomach - Fibroblasts, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Secreted to blood" Enzyme NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 36: Choroid plexus - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 108: Fibroblasts - ECM organization" 24 "unprognostic (3.30e-2)" "unprognostic (3.06e-2)" "unprognostic (1.55e-1)" "unprognostic (1.07e-1)" "unprognostic (1.07e-1)" "unprognostic (7.88e-2)" "unprognostic (2.82e-1)" "unprognostic (4.31e-2)" "unprognostic (8.63e-2)" "potential prognostic unfavorable (1.36e-4)" "unprognostic (2.29e-2)" "unprognostic (2.93e-2)" "unprognostic (6.14e-2)" "unprognostic (3.42e-3)" "unprognostic (3.30e-3)" "unprognostic (1.14e-1)" "unprognostic (1.20e-1)" "unprognostic (7.21e-2)" "unprognostic (3.57e-1)" "unprognostic (2.82e-1)" "unprognostic (1.81e-1)" "unprognostic (3.82e-1)" "unprognostic (1.04e-2)" "unprognostic (1.69e-2)" "unprognostic (2.08e-1)" "unprognostic (6.76e-2)" "unprognostic (2.56e-2)" "unprognostic (1.52e-3)" "unprognostic (1.98e-1)" "unprognostic (1.27e-2)" "unprognostic (3.86e-1)" GPX8 "EPLA847, UNQ847" ENSG00000164294 "Glutathione peroxidase 8 (putative)" Q8TED1 5 55160167-55167297 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast lactating cells: 53.4;Cytotrophoblasts: 58.0;Decidual stromal cells: 111.8;Endometrial stromal cells: 52.8;Epididymal principal cells: 51.5;Extravillous trophoblasts: 310.2;Fibroblasts: 76.5;Hepatic stellate cells: 58.1;Melanocytes: 50.4;Migrating cytotrophoblasts: 94.4;Respiratory deuterosomal cells: 64.3" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 12.5;fibroblast: 29.5;pericyte: 12.1;vascular associated smooth muscle cell: 9.2" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "choroid plexus: 13.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Adrenal gland - Fibroblasts, Breast - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblasts_2, Pituitary gland - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036720 Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 8: Immune cells - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 180 "Plasma membrane, Cytosol" "Actin filaments" "HPA036720: " "unprognostic (5.47e-2)" "unprognostic (4.97e-2)" "unprognostic (3.53e-1)" "unprognostic (1.57e-2)" "unprognostic (5.65e-2)" "unprognostic (3.13e-2)" "unprognostic (3.93e-2)" "potential prognostic unfavorable (6.08e-7)" "unprognostic (1.85e-3)" "unprognostic (4.61e-2)" "unprognostic (2.28e-3)" "potential prognostic unfavorable (7.19e-4)" "unprognostic (1.46e-2)" "unprognostic (6.56e-3)" "unprognostic (6.07e-2)" "potential prognostic unfavorable (1.03e-5)" "unprognostic (3.32e-3)" "unprognostic (2.68e-1)" "unprognostic (4.59e-2)" "unprognostic (1.12e-1)" "potential prognostic unfavorable (2.84e-5)" "unprognostic (1.45e-2)" "unprognostic (3.81e-3)" "unprognostic (1.88e-1)" "unprognostic (4.12e-2)" "unprognostic (5.09e-1)" "unprognostic (9.88e-3)" "unprognostic (5.56e-3)" "unprognostic (1.53e-2)" "unprognostic (1.38e-2)" "unprognostic (2.33e-1)" GRAMD1A "FLJ90346, KIAA1533" ENSG00000089351 "GRAM domain containing 1A" Q96CP6 19 34994784-35026471 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Autophagy, Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Neutrophils: 679.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008852, HPA012570" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 18: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 16 "Plasma membrane" Cytosol "HPA008852: , HPA012570: " "unprognostic (3.07e-1)" "unprognostic (2.13e-1)" "unprognostic (2.52e-2)" "potential prognostic unfavorable (5.08e-4)" "unprognostic (1.93e-1)" "unprognostic (1.37e-1)" "unprognostic (1.04e-1)" "unprognostic (2.44e-1)" "unprognostic (2.08e-1)" "unprognostic (3.31e-2)" "potential prognostic unfavorable (5.73e-4)" "unprognostic (1.63e-1)" "potential prognostic unfavorable (2.57e-4)" "potential prognostic unfavorable (1.40e-4)" "unprognostic (3.97e-2)" "unprognostic (2.05e-3)" "unprognostic (2.83e-1)" "unprognostic (1.67e-2)" "unprognostic (4.76e-1)" "unprognostic (3.50e-3)" "unprognostic (9.85e-2)" "unprognostic (1.48e-1)" "unprognostic (1.25e-1)" "unprognostic (4.72e-2)" "unprognostic (3.79e-2)" "unprognostic (3.13e-1)" "unprognostic (2.03e-1)" "unprognostic (1.32e-1)" "unprognostic (6.78e-2)" "unprognostic (1.67e-1)" "unprognostic (1.35e-1)" GRAMD1B "KIAA1201, LINC01059" ENSG00000023171 "GRAM domain containing 1B" Q3KR37 11 123358428-123627774 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 204.1;brain: 111.7;retina: 89.2" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 1195.6;Cardiomyocytes: 381.5;Choroid plexus epithelial cells: 912.9;Cone photoreceptor cells: 1246.2;Cytotrophoblasts: 362.6;Distal convoluted tubule cells: 604.7;pDCs: 517.8;Proximal tubule cells: 975.5;Rod photoreceptor cells: 765.1" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 771.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "plasmacytoid DC: 6.8" "Lineage enriched" "Detected in many" 4 "dendritic cells: 6.8" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 69.7" "Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Liver - Cholangiocytes, Pituitary gland - Lactotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008557, HPA075204" Approved Supported "Endoplasmic reticulum,Vesicles,Plasma membrane" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 5: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 79: Photoreceptor cells - Phototransduction" 7 "Endoplasmic reticulum, Plasma membrane" Vesicles "HPA008557: , HPA075204: " "unprognostic (5.34e-2)" "unprognostic (2.07e-1)" "unprognostic (3.76e-2)" "unprognostic (2.33e-2)" "unprognostic (8.97e-2)" "unprognostic (7.37e-2)" "unprognostic (1.87e-1)" "unprognostic (1.23e-3)" "unprognostic (8.09e-3)" "unprognostic (1.73e-2)" "potential prognostic unfavorable (9.44e-4)" "unprognostic (8.42e-2)" "unprognostic (4.10e-3)" "unprognostic (1.79e-3)" "unprognostic (3.36e-1)" "unprognostic (2.80e-3)" "unprognostic (9.67e-2)" "unprognostic (3.31e-2)" "unprognostic (4.66e-2)" "unprognostic (2.68e-1)" "unprognostic (1.01e-3)" "unprognostic (1.13e-1)" "unprognostic (2.08e-1)" "unprognostic (2.57e-1)" "unprognostic (2.73e-1)" "unprognostic (2.79e-1)" "unprognostic (4.09e-2)" "unprognostic (6.18e-2)" "unprognostic (1.67e-1)" "unprognostic (6.70e-2)" GRAMD1C DKFZp434C0328 ENSG00000178075 "GRAM domain containing 1C" Q8IYS0 3 113828182-113947174 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 322.7;Endometrial glandular cells: 267.2;Late spermatids: 153.6;Pituitary stem cells: 182.9" "Cell type enhanced" "Detected in all" "astrocyte: 343.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "memory B-cell: 2.7;naive B-cell: 3.0;neutrophil: 2.1" "Group enriched" "Detected in many" 13 "B-cells: 3.0;granulocytes: 2.1" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Liver - Hepatocytes, Stomach - Parietal cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA012316 Approved Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 36: Brain & Liver - Signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 51: Secretory epithelial cells - Mixed function" 8 "Plasma membrane, Cytosol" "HPA012316: " "unprognostic (3.45e-1)" "unprognostic (3.11e-2)" "unprognostic (7.89e-2)" "unprognostic (3.84e-2)" "unprognostic (1.76e-1)" "unprognostic (5.21e-2)" "unprognostic (7.78e-2)" "unprognostic (1.37e-1)" "unprognostic (2.09e-2)" "unprognostic (1.40e-1)" "potential prognostic favorable (1.07e-10)" "unprognostic (3.15e-3)" "potential prognostic favorable (1.46e-4)" "unprognostic (3.67e-3)" "unprognostic (7.24e-3)" "unprognostic (4.70e-1)" "unprognostic (1.13e-1)" "unprognostic (3.11e-1)" "unprognostic (1.56e-1)" "unprognostic (1.02e-1)" "unprognostic (1.74e-1)" "unprognostic (7.88e-3)" "unprognostic (1.16e-2)" "unprognostic (2.00e-1)" "unprognostic (3.47e-1)" "unprognostic (2.38e-1)" "unprognostic (3.91e-2)" "unprognostic (1.31e-1)" "unprognostic (1.87e-1)" "unprognostic (1.47e-1)" GRAMD2A GRAMD2 ENSG00000175318 "GRAM domain containing 2A" Q8IUY3 15 72159806-72197787 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 33.9;placenta: 45.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 76.9;Cytotrophoblasts: 223.0;Endometrial ciliated cells: 44.8;Ependymal cells: 146.4;Epididymal basal cells: 46.1;Epididymal efferent duct ciliated cells: 53.3;Migrating cytotrophoblasts: 131.2;Respiratory ciliated cells: 48.4;Syncytiotrophoblasts: 210.7" "Cell type enriched" "Detected in many" 11 "ependymal cell: 182.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 13.0" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA029435 Uncertain Approved "Nucleoli,Nuclear speckles,Cytosol" NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 46: Brainstem - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 4 "Nucleoli, Nuclear speckles" Cytosol "HPA029435: " "unprognostic (6.32e-3)" "unprognostic (1.02e-1)" "unprognostic (1.04e-1)" "unprognostic (5.39e-2)" "unprognostic (1.62e-1)" "unprognostic (3.10e-3)" "unprognostic (4.53e-2)" "unprognostic (1.56e-1)" "unprognostic (4.64e-2)" "unprognostic (1.22e-2)" "unprognostic (1.82e-1)" "unprognostic (1.14e-2)" "unprognostic (8.45e-2)" "unprognostic (1.37e-2)" "unprognostic (1.51e-1)" "unprognostic (3.72e-2)" "unprognostic (5.51e-2)" "unprognostic (2.38e-1)" "unprognostic (2.72e-2)" "unprognostic (1.00e-2)" "potential prognostic favorable (4.95e-4)" "unprognostic (3.14e-1)" "unprognostic (1.69e-1)" "unprognostic (7.49e-3)" "unprognostic (5.46e-2)" GRAMD2B "FLJ21313, GRAMD3, NS3TP2" ENSG00000155324 "GRAM domain containing 2B" Q96HH9 5 126360132-126496494 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 656.8;Endometrial glandular cells: 902.3;Ependymal cells: 629.7" "Cell type enhanced" "Detected in many" "astrocyte: 885.9;ependymal cell: 656.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 2.9;MAIT T-cell: 2.9;memory CD4 T-cell: 1.6;memory CD8 T-cell: 2.3;myeloid DC: 1.7;naive CD4 T-cell: 3.0;naive CD8 T-cell: 1.8;NK-cell: 1.1;plasmacytoid DC: 4.3;T-reg: 2.4" "Group enriched" "Detected in many" 6 "dendritic cells: 4.3;NK-cells: 1.1;T-cells: 3.0" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009678, HPA010095" Enhanced Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 51: Secretory epithelial cells - Mixed function" 18 Cytosol "Nucleoplasm, Golgi apparatus" "HPA009678: , HPA010095: " "unprognostic (2.22e-1)" "unprognostic (3.05e-1)" "unprognostic (8.86e-2)" "unprognostic (4.44e-2)" "unprognostic (1.87e-1)" "unprognostic (1.95e-1)" "unprognostic (2.67e-1)" "unprognostic (6.63e-2)" "unprognostic (7.38e-2)" "potential prognostic favorable (8.95e-10)" "unprognostic (1.18e-3)" "unprognostic (1.29e-1)" "unprognostic (2.26e-1)" "unprognostic (8.46e-2)" "unprognostic (3.92e-3)" "unprognostic (2.16e-1)" "unprognostic (1.25e-2)" "unprognostic (1.66e-1)" "unprognostic (2.62e-2)" "unprognostic (6.90e-3)" "unprognostic (4.27e-2)" "unprognostic (3.31e-1)" "unprognostic (5.52e-3)" "unprognostic (1.32e-1)" "unprognostic (1.05e-1)" "unprognostic (4.90e-2)" "unprognostic (1.30e-1)" "unprognostic (1.81e-1)" "unprognostic (2.59e-2)" GRAMD4 "DIP, KIAA0767" ENSG00000075240 "GRAM domain containing 4" Q6IC98 22 46576012-46679790 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 167.3" "Cell type enhanced" "Detected in many" "Enterocytes: 119.6;Megakaryocyte-Erythroid progenitors: 121.1;Pancreatic islet cells: 127.3;Thymocytes: 132.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 77: Intestine - Digestion" "Cluster 51: Neurons - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 12 "unprognostic (6.26e-2)" "unprognostic (5.94e-3)" "potential prognostic favorable (9.85e-4)" "unprognostic (8.35e-2)" "potential prognostic favorable (5.14e-4)" "unprognostic (2.34e-1)" "unprognostic (3.19e-1)" "unprognostic (3.08e-2)" "unprognostic (1.83e-3)" "unprognostic (3.42e-2)" "unprognostic (3.58e-1)" "unprognostic (1.25e-2)" "potential prognostic favorable (1.36e-4)" "unprognostic (3.21e-1)" "unprognostic (2.48e-1)" "unprognostic (6.74e-2)" "unprognostic (2.14e-1)" "unprognostic (1.34e-1)" "unprognostic (5.60e-2)" "potential prognostic unfavorable (5.76e-4)" "unprognostic (3.33e-1)" "unprognostic (4.36e-2)" "unprognostic (9.65e-2)" "unprognostic (2.06e-1)" "unprognostic (3.43e-2)" "unprognostic (3.51e-1)" "unprognostic (5.84e-2)" "unprognostic (9.59e-2)" "unprognostic (1.46e-1)" "unprognostic (1.67e-2)" "potential prognostic favorable (8.62e-4)" GRAP ENSG00000154016 "GRB2 related adaptor protein" Q13588 17 19020656-19047011 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 50.1" "Cell type enhanced" "Detected in some" "B-cells: 26.3;Epididymal basal cells: 6.7;Hematopoietic stem cells: 8.2;Hofbauer cells: 18.2;Lymphatic endothelial cells: 49.4;Megakaryocytes: 6.2;Microglia: 6.0;T-cells: 6.5;Thymocytes: 7.6;Vascular endothelial cells: 13.3" "Group enriched" "Detected in some" 12 "central nervous system macrophage: 5.8;endothelial cell: 22.6;leukocyte: 9.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 5 "B-cells: 100.0;T-cells: 134.0" "Group enriched" "Detected in some" 10 "Leukemia: 14.8;lymphoma: 40.4" "Heart muscle - Endothelial cells, Kidney - Endothelial cells, Skeletal muscle - Endothelial cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA046595, HPA066654" Uncertain Approved Centrosome NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 6 Centrosome "HPA046595: , HPA066654: " "unprognostic (1.61e-1)" "unprognostic (9.72e-2)" "unprognostic (9.77e-3)" "unprognostic (5.64e-3)" "unprognostic (7.20e-3)" "unprognostic (1.80e-1)" "unprognostic (1.35e-1)" "unprognostic (1.95e-1)" "potential prognostic favorable (1.55e-5)" "unprognostic (1.91e-1)" "unprognostic (2.15e-2)" "unprognostic (7.93e-3)" "unprognostic (1.08e-2)" "unprognostic (3.04e-2)" "unprognostic (1.43e-3)" "unprognostic (1.15e-2)" "unprognostic (2.37e-2)" "unprognostic (4.49e-2)" "unprognostic (2.27e-1)" "unprognostic (1.43e-1)" "unprognostic (1.15e-1)" "unprognostic (7.84e-2)" "unprognostic (1.10e-3)" "unprognostic (7.18e-2)" "unprognostic (2.18e-2)" "unprognostic (2.04e-1)" "unprognostic (3.75e-2)" "unprognostic (9.42e-2)" "unprognostic (2.91e-2)" "unprognostic (2.36e-1)" "unprognostic (4.59e-2)" GRAP2 "GADS, GRBLG, GrbX, Grf40, Mona" ENSG00000100351 "GRB2 related adaptor protein 2" O75791 22 39901084-39973721 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 18 "lymphoid tissue: 171.9" "Cell type enriched" "Detected in many" 4 "Platelets: 1719.7" "Cell type enriched" "Detected in many" 130 "leukocyte: 471.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 7 "gdT-cell: 51.5;MAIT T-cell: 38.3;memory CD4 T-cell: 37.6;memory CD8 T-cell: 56.2;naive CD4 T-cell: 31.3;naive CD8 T-cell: 58.4;T-reg: 35.1" "Lineage enriched" "Detected in many" 9 "T-cells: 58.4" "Cancer enriched" "Detected in some" 6 "Leukemia: 29.3" "Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Kidney - T-cells, Pancreas - T-cells, Pituitary gland - T-cells, Spleen - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA005788, CAB022073" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 330000 "Cluster 11: T-cells - Unknown function" "Cluster 80: Thymus - Adaptive immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 58: Mast cells - Allergic inflammatory responses" 74 "Nucleoplasm, Cytosol" "Plasma membrane" "CAB022073: , HPA005788: " "unprognostic (1.06e-3)" "unprognostic (6.54e-2)" "unprognostic (1.53e-1)" "unprognostic (2.14e-2)" "unprognostic (1.99e-1)" "potential prognostic favorable (2.28e-4)" "unprognostic (4.20e-2)" "unprognostic (3.44e-2)" "unprognostic (1.53e-2)" "potential prognostic favorable (6.13e-5)" "unprognostic (4.08e-2)" "unprognostic (1.84e-1)" "unprognostic (1.66e-1)" "potential prognostic favorable (8.90e-4)" "unprognostic (2.51e-2)" "unprognostic (1.84e-1)" "unprognostic (1.34e-1)" "unprognostic (9.46e-3)" "unprognostic (4.44e-2)" "unprognostic (1.19e-1)" "unprognostic (3.39e-2)" GRAPL ENSG00000189152 "GRB2 related adaptor protein like" Q8TC17 17 19127535-19159187 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 10.7;lymphoid tissue: 24.2" "Group enriched" "Detected in some" 7 "B-cells: 17.3;Lymphatic endothelial cells: 33.8;Vascular endothelial cells: 8.8" "Group enriched" "Detected in some" 7 "central nervous system macrophage: 3.0;endothelial cell: 10.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 9.1" "Lineage enriched" "Detected in many" 6 "B-cells: 9.1" "Group enriched" "Detected in some" 6 "Leukemia: 7.2;lymphoma: 23.5" "HPA051796, HPA066654" Uncertain Approved Centrosome NA NA "Cluster 18: Non-specific - Translation" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 105: Non-specific - Mixed function" 3 Centrosome "HPA051796: , HPA066654: " "unprognostic (2.58e-1)" "unprognostic (1.08e-1)" "unprognostic (2.87e-2)" "unprognostic (1.84e-1)" "unprognostic (2.24e-2)" "unprognostic (7.60e-3)" "unprognostic (1.42e-2)" "unprognostic (8.08e-2)" "unprognostic (1.54e-1)" "unprognostic (3.83e-3)" "unprognostic (2.22e-1)" "unprognostic (3.65e-1)" "unprognostic (2.42e-3)" "unprognostic (2.68e-1)" "unprognostic (4.28e-2)" "unprognostic (2.63e-1)" "unprognostic (1.60e-1)" "unprognostic (9.91e-2)" GRB10 ENSG00000106070 "Growth factor receptor bound protein 10" Q13322 7 50590063-50793462 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 691.4;Neutrophils: 1211.8;Pancreatic acinar cells: 742.8;Rod photoreceptor cells: 652.7;Vascular endothelial cells: 441.7" "Cell type enhanced" "Detected in all" "endothelial cell: 604.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "basophil: 10.1;eosinophil: 3.0" "Lineage enriched" "Detected in single" 29 "granulocytes: 10.1" "Low cancer specificity" "Detected in many" "Heart muscle - Endothelial cells, Prostate - Endothelial cells, Stomach - Endothelial cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019423, HPA027502, HPA031818" Enhanced Supported Vesicles NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 70: Non-specific - Protein processing" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 67: Non-specific - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" 37 Vesicles "CAB019423: , HPA027502: , HPA031818: " "unprognostic (1.66e-1)" "unprognostic (4.61e-3)" "unprognostic (4.14e-2)" "potential prognostic unfavorable (7.76e-4)" "unprognostic (4.51e-2)" "unprognostic (1.69e-2)" "unprognostic (1.02e-1)" "potential prognostic unfavorable (1.08e-4)" "unprognostic (1.21e-1)" "unprognostic (1.65e-2)" "validated prognostic favorable (7.52e-8)" "validated prognostic favorable (1.44e-4)" "unprognostic (4.38e-1)" "unprognostic (1.62e-2)" "unprognostic (1.79e-1)" "validated prognostic unfavorable (1.67e-4)" "validated prognostic unfavorable (8.39e-4)" "unprognostic (4.54e-1)" "unprognostic (4.83e-2)" "unprognostic (2.37e-2)" "unprognostic (2.80e-1)" "unprognostic (1.19e-1)" "unprognostic (2.61e-3)" "unprognostic (1.21e-1)" "unprognostic (2.53e-1)" "unprognostic (1.04e-1)" "unprognostic (2.05e-2)" "unprognostic (6.63e-3)" "unprognostic (2.54e-2)" "unprognostic (3.06e-2)" "unprognostic (2.34e-2)" GRB14 ENSG00000115290 "Growth factor receptor bound protein 14" Q14449 2 164492417-164621482 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 23.8;liver: 29.1;tongue: 43.3" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 117.0;Cardiomyocytes: 148.6;Distal convoluted tubule cells: 461.9;Epididymal clear cells: 144.9;Hepatocytes: 138.2;Loop of henle epithelial cells: 161.5;Renal collecting duct intercalated cells: 564.6;Renal connecting tubule cells: 161.7;Sertoli cells: 253.5" "Cell type enhanced" "Detected in many" "miscellaneous: 136.0" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 10.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 8.0" "Colon - Enteric glia cells, Liver - Hepatocytes, Pituitary gland - Thyrotropes, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB022294, HPA035052, HPA035053" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 76: Non-specific - Metabolism" "Cluster 51: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 7 "Nucleoplasm, Cytosol" "CAB022294: , HPA035052: , HPA035053: " "unprognostic (4.45e-2)" "unprognostic (1.51e-1)" "unprognostic (2.00e-1)" "unprognostic (3.48e-2)" "potential prognostic favorable (3.52e-6)" "unprognostic (3.99e-2)" "unprognostic (9.28e-2)" "unprognostic (1.66e-1)" "unprognostic (3.77e-2)" "unprognostic (8.10e-2)" "unprognostic (2.37e-1)" "potential prognostic favorable (1.12e-6)" "unprognostic (5.17e-3)" "unprognostic (1.54e-2)" GRB2 NCKAP2 ENSG00000177885 "Growth factor receptor bound protein 2" P62993 17 75318076-75405709 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "cDC: 523.0;Extravillous trophoblasts: 580.4;monocytes: 836.3;Neutrophil progenitors: 693.8;Neutrophils: 2323.7" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 404.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002589, HPA003991" Approved Supported Centrosome,Cytosol NA NA 2300000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 51: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 462 Cytosol Centrosome "CAB002589: , HPA003991: " "unprognostic (8.84e-3)" "unprognostic (1.40e-2)" "unprognostic (2.76e-1)" "unprognostic (3.00e-2)" "unprognostic (1.39e-1)" "unprognostic (4.66e-2)" "unprognostic (1.26e-1)" "unprognostic (1.54e-2)" "unprognostic (2.32e-1)" "unprognostic (2.32e-2)" "unprognostic (6.74e-3)" "unprognostic (1.90e-1)" "unprognostic (1.04e-1)" "validated prognostic unfavorable (4.13e-8)" "validated prognostic unfavorable (8.14e-4)" "unprognostic (8.07e-2)" "unprognostic (1.24e-2)" "unprognostic (7.56e-2)" "unprognostic (1.09e-1)" "unprognostic (1.51e-1)" "unprognostic (5.20e-2)" "unprognostic (1.39e-1)" "unprognostic (7.08e-2)" "potential prognostic unfavorable (5.98e-4)" "unprognostic (1.46e-1)" "unprognostic (2.11e-2)" "unprognostic (1.35e-1)" "unprognostic (7.14e-2)" "unprognostic (2.11e-2)" "unprognostic (1.11e-1)" "unprognostic (1.99e-1)" GRB7 ENSG00000141738 "Growth factor receptor bound protein 7" Q14451 17 39737927-39747291 "Cancer-related genes, Predicted intracellular proteins" "Repressor, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 58.0;kidney: 59.1" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 384.1;Esophageal basal cells: 142.9;Esophageal suprabasal cells: 174.9;Ocular epithelial cells: 121.6;Paneth cells: 143.1;Prostatic club cells: 121.3;Prostatic hillock cells: 132.1;Syncytiotrophoblasts: 152.5" "Group enriched" "Detected in some" 4 "choroid plexus epithelial cell: 10.0;upper rhombic lip: 5.7" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 9 "cerebellum: 11.6;choroid plexus: 9.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 130.5;Esophageal cancer: 160.3" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Pituitary gland - Somatotropes" "Region enhanced" "Detected in many" "cerebellum: 8.3" "Low region specificity" "Detected in all" "CAB005226, HPA057084, CAB073538" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 5: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 26: Keratinocytes - Keratinization" 41 "Plasma membrane, Cytosol" "CAB005226: , CAB073538: , HPA057084: " "unprognostic (6.98e-2)" "unprognostic (6.82e-2)" "unprognostic (1.78e-1)" "unprognostic (1.82e-1)" "unprognostic (5.01e-2)" "unprognostic (7.86e-2)" "unprognostic (3.53e-2)" "unprognostic (8.56e-2)" "potential prognostic favorable (2.10e-4)" "unprognostic (1.49e-2)" "unprognostic (2.98e-1)" "unprognostic (6.68e-2)" "unprognostic (5.05e-3)" "unprognostic (3.43e-1)" "unprognostic (8.08e-2)" "unprognostic (1.34e-1)" "unprognostic (2.28e-1)" "unprognostic (1.24e-3)" "unprognostic (3.41e-1)" "potential prognostic unfavorable (7.07e-4)" "unprognostic (1.43e-2)" "unprognostic (2.93e-1)" "unprognostic (6.09e-3)" "unprognostic (7.17e-3)" "unprognostic (2.01e-1)" "unprognostic (2.05e-2)" "unprognostic (4.27e-2)" "unprognostic (3.55e-3)" "unprognostic (4.74e-3)" GREB1 KIAA0575 ENSG00000196208 "Growth regulating estrogen receptor binding 1" Q4ZG55 2 11482341-11642788 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "ovary: 255.7" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 166.0;Endometrial stromal cells: 128.1;Gonadotrophs: 247.4;Granulosa cells: 283.8;Ovarian stromal cells: 709.0;Peritubular myoid cells: 126.1;Prostatic glandular cells: 742.8;Sertoli cells: 146.5" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 55.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 38.4;Neuroblastoma: 28.9;skin cancer: 32.2" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Lung - Fibroblasts_2, Prostate - Prostate glandular cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" "HPA024616, HPA027843, HPA028416" Uncertain Approved Mitochondria,Cytosol NA NA "Cluster 75: Ovary - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 27: Breast cancer - Unknown function" "Cluster 94: Gonadal somatic cells - Mixed function" 1 "Mitochondria, Cytosol" "HPA024616: , HPA027843: , HPA028416: " "unprognostic (1.25e-1)" "unprognostic (3.30e-2)" "unprognostic (2.75e-1)" "unprognostic (4.13e-2)" "unprognostic (3.12e-3)" "unprognostic (2.03e-2)" "unprognostic (1.36e-1)" "unprognostic (4.40e-3)" "unprognostic (4.24e-3)" "unprognostic (1.57e-1)" "unprognostic (1.72e-2)" "unprognostic (1.39e-2)" "unprognostic (8.36e-2)" "unprognostic (6.13e-2)" "unprognostic (4.45e-2)" "unprognostic (2.27e-2)" "unprognostic (1.87e-1)" "unprognostic (2.63e-1)" "unprognostic (3.33e-1)" "unprognostic (3.71e-2)" "unprognostic (1.17e-1)" "unprognostic (1.18e-2)" "unprognostic (6.01e-2)" "unprognostic (1.75e-2)" "unprognostic (2.87e-1)" "unprognostic (1.87e-3)" "potential prognostic favorable (6.57e-4)" GREB1L "C18orf6, FLJ13687, KIAA1772" ENSG00000141449 "GREB1 like retinoic acid receptor coactivator" Q9C091 18 21242232-21526112 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 8.3" "Cell type enhanced" "Detected in many" "Bergmann glia: 524.0;Fibro-adipogenic progenitors: 330.7;Gonadotrophs: 394.8;Leydig cells: 756.0;Myonuclei: 845.7;Oligodendrocytes: 269.1;Peritubular myoid cells: 693.8;Pituicytes/FSCs: 391.8;Renal collecting duct principal cells: 426.3;Retinal amacrine cells: 640.4;Retinal bipolar cells: 438.4" "Cell type enhanced" "Detected in all" "Bergmann glia: 572.9" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 4.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipocytes (Visceral), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA041647, HPA044218" Uncertain Approved Mitochondria NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 34: Testis cancer - Unknown function" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 2 Mitochondria "HPA041647: , HPA044218: " "unprognostic (7.86e-2)" "unprognostic (4.15e-3)" "unprognostic (4.11e-2)" "potential prognostic favorable (7.48e-4)" "potential prognostic favorable (2.24e-5)" "unprognostic (1.20e-1)" "unprognostic (3.48e-1)" "unprognostic (3.60e-2)" "potential prognostic unfavorable (1.04e-4)" "unprognostic (3.22e-2)" "validated prognostic unfavorable (2.70e-4)" "validated prognostic unfavorable (5.23e-6)" "unprognostic (4.89e-2)" "unprognostic (2.84e-1)" "unprognostic (1.32e-1)" GREM1 "CKTSF1B1, CRAC1, DAND2, DRM, gremlin, HMPS" ENSG00000166923 "Gremlin 1, DAN family BMP antagonist" O60565 15 32718004-32745106 "Disease related genes, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 105.6;intestine: 59.9;smooth muscle: 63.6;vagina: 63.4" "Group enriched" "Detected in some" 11 "Oligodendrocytes: 91.6;Renal collecting duct principal cells: 49.3" "Group enriched" "Detected in many" 5 "cerebellar inhibitory: 34.3;committed oligodendrocyte precursor: 39.7;oligodendrocyte: 102.3" "Cancer enhanced" "Detected in many" "Stomach Adenocarcinoma (TCGA): 30.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 31.2;thyroid cancer: 33.0" "Spleen - Smooth muscle cells, Testis - Spermatogonia" "Group enriched" "Detected in many" 5 "hippocampal formation: 3.2;olfactory bulb: 10.9" "Low region specificity" "Detected in many" HPA007526 Uncertain "Secreted to blood" Cytokine NA NA 242000000 "Cluster 11: Esophagus - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 4 "HPA007526: " "unprognostic (9.69e-3)" "unprognostic (4.10e-2)" "unprognostic (2.50e-2)" "unprognostic (4.68e-3)" "unprognostic (1.87e-1)" "unprognostic (2.53e-2)" "unprognostic (1.80e-1)" "unprognostic (1.92e-1)" "unprognostic (2.32e-1)" "unprognostic (6.09e-2)" "unprognostic (3.63e-3)" "unprognostic (3.34e-3)" "unprognostic (2.71e-3)" "potential prognostic unfavorable (3.86e-4)" "unprognostic (2.05e-2)" "unprognostic (8.14e-2)" "unprognostic (1.70e-1)" "unprognostic (9.64e-2)" "unprognostic (1.63e-2)" "unprognostic (5.11e-3)" "unprognostic (6.45e-2)" GREM2 "CKTSF1B2, DAND3, FLJ21195, Prdc" ENSG00000180875 "Gremlin 2, DAN family BMP antagonist" Q9H772 1 240489573-240612155 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Cytokine, Developmental protein, Heparin-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 29.4;liver: 24.6" "Cell type enhanced" "Detected in many" "Breast lactating cells: 564.8;Cone photoreceptor cells: 80.7;Parietal cells: 81.3;Retinal bipolar cells: 104.0;Salivary acinar cells: 173.0;Somatotrophs: 213.4;Syncytiotrophoblasts: 885.6;Thymic myoid cells: 213.5" "Cell type enhanced" "Detected in many" "midbrain-derived inhibitory: 433.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 6.6" "Kidney - Fibroblasts, Pituitary gland - Somatotropes, Skeletal muscle - Skeletal myocytes, Spleen - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" CAB009920 Approved "Secreted to blood" Cytokine NA NA 1200000 "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 8 "CAB009920: " "unprognostic (8.73e-2)" "unprognostic (2.16e-1)" "unprognostic (8.34e-2)" "unprognostic (1.24e-1)" "unprognostic (8.76e-2)" "unprognostic (1.20e-1)" "unprognostic (1.76e-1)" "unprognostic (8.61e-2)" "unprognostic (2.78e-1)" "unprognostic (3.26e-1)" "unprognostic (2.44e-2)" "unprognostic (4.95e-2)" "unprognostic (3.22e-1)" "unprognostic (2.51e-1)" "unprognostic (1.59e-1)" "unprognostic (3.30e-2)" GREP1 "G029442, LINC00514" ENSG00000262152 "Glycine rich extracellular protein 1" 16 2988256-3002016 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "lymphoid tissue: 2.4;skin 1: 3.5" "Cell type enriched" "Detected in some" 28 "Medullary thymic epithelial cells: 28.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "cerebellum: 8.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "breast cancer: 14.5;colorectal cancer: 4.1;Esophageal cancer: 4.3;head and neck cancer: 6.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 49: Non-specific - Transcription" "Cluster 35: Non-specific - DNA binding" "Cluster 27: Breast cancer - Unknown function" "Cluster 26: Keratinocytes - Keratinization" "unprognostic (1.59e-1)" "unprognostic (2.37e-1)" "unprognostic (3.28e-2)" "unprognostic (3.99e-2)" "unprognostic (8.73e-3)" "unprognostic (1.93e-1)" "potential prognostic unfavorable (1.26e-5)" "unprognostic (3.43e-1)" "unprognostic (1.46e-1)" "unprognostic (9.71e-2)" GRHL1 "LBP-32, MGR, TFCP2L2" ENSG00000134317 "Grainyhead like transcription factor 1" Q9NZI5 2 9951693-10002277 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 114.7;skin 1: 84.6;vagina: 65.5" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 1073.6;Esophageal suprabasal cells: 303.9;Extravillous trophoblasts: 165.7;Ocular epithelial cells: 195.2;Prostatic hillock cells: 213.4;Suprabasal keratinocytes: 326.8;Syncytiotrophoblasts: 288.7;Urothelial cells: 238.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 2.2" "Lineage enriched" "Detected in single" 8 "granulocytes: 2.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA005798, HPA006420" Enhanced Supported Nucleoplasm,Vesicles NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 34: Testis cancer - Unknown function" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 2 Nucleoplasm Vesicles "HPA005798: , HPA006420: " "unprognostic (2.63e-1)" "unprognostic (4.84e-3)" "unprognostic (2.97e-2)" "unprognostic (1.58e-1)" "unprognostic (5.84e-2)" "unprognostic (2.43e-1)" "unprognostic (3.54e-1)" "potential prognostic favorable (9.61e-5)" "unprognostic (5.60e-2)" "unprognostic (1.35e-1)" "unprognostic (1.02e-2)" "unprognostic (1.88e-3)" "unprognostic (9.38e-3)" "unprognostic (1.79e-2)" "unprognostic (2.00e-1)" "unprognostic (1.90e-1)" "unprognostic (3.76e-3)" "unprognostic (2.24e-2)" "unprognostic (3.10e-2)" "unprognostic (5.05e-2)" "unprognostic (2.52e-1)" "unprognostic (1.13e-1)" "unprognostic (4.90e-2)" "unprognostic (1.92e-1)" "unprognostic (4.23e-2)" "unprognostic (1.17e-2)" "unprognostic (9.88e-2)" "unprognostic (1.52e-1)" "unprognostic (1.91e-1)" "unprognostic (5.60e-2)" "unprognostic (1.52e-3)" GRHL2 "BOM, DFNA28, FLJ13782, TFCP2L3" ENSG00000083307 "Grainyhead like transcription factor 2" Q6ISB3 8 101492439-101669726 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Corneal dystrophy, Deafness, Disease variant, Dwarfism, Ectodermal dysplasia, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 27.0" "Cell type enhanced" "Detected in many" "Prostatic glandular cells: 959.5;Respiratory ciliated cells: 321.0;Salivary ionocytes: 296.0" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Liver - Cholangiocytes, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Skin - Keratinocyte (other), Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA004820, HPA062839" Uncertain Supported Nucleoplasm NA NA "Cluster 58: Skin - Keratinization" "Cluster 53: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 7 Nucleoplasm "HPA004820: , HPA062839: " "unprognostic (7.47e-2)" "potential prognostic unfavorable (3.29e-4)" "unprognostic (1.05e-1)" "unprognostic (2.19e-1)" "unprognostic (8.82e-2)" "unprognostic (1.36e-1)" "unprognostic (5.39e-2)" "unprognostic (1.11e-2)" "unprognostic (1.42e-1)" "unprognostic (2.00e-1)" "unprognostic (7.56e-2)" "unprognostic (3.22e-1)" "unprognostic (1.61e-2)" "unprognostic (1.21e-1)" "unprognostic (1.86e-1)" "potential prognostic unfavorable (4.24e-4)" "unprognostic (1.09e-2)" "unprognostic (3.51e-2)" "unprognostic (4.59e-3)" "unprognostic (3.18e-1)" "unprognostic (8.55e-2)" "unprognostic (1.20e-2)" "unprognostic (4.12e-1)" "unprognostic (9.44e-2)" "unprognostic (1.21e-1)" GRHL3 "SOM, TFCP2L4" ENSG00000158055 "Grainyhead like transcription factor 3" Q8TE85 1 24199558-24364482 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 102.2;skin 1: 49.4;vagina: 42.5" "Cell type enhanced" "Detected in many" "Epididymal basal cells: 77.8;Esophageal apical cells: 537.9;Esophageal basal cells: 64.0;Esophageal suprabasal cells: 251.2;Ocular epithelial cells: 193.1;Suprabasal keratinocytes: 215.5;Urothelial cells: 304.3" "Group enriched" "Detected in some" 4 "astrocyte: 4.2;central nervous system macrophage: 1.9" "Group enriched" "Detected in many" 9 "Bladder Urothelial Carcinoma (TCGA): 54.4;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 30.6;Head and Neck Squamous Cell Carcinoma (TCGA): 34.8;Lung Squamous Cell Carcinoma (TCGA): 19.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 37.7;testis cancer: 30.1" "Adipose visceral - Mesothelial cells, Prostate - Urothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA059960 Enhanced Supported "Nucleoplasm,Actin filaments,Primary cilium,Cytosol" NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 69: Urothelial cells - Basic cellular functions" 8 Nucleoplasm "Actin filaments, Primary cilium, Cytosol" "HPA059960: " "potential prognostic favorable (9.54e-5)" "unprognostic (1.51e-1)" "unprognostic (1.36e-1)" "unprognostic (2.27e-1)" "unprognostic (9.36e-2)" "unprognostic (2.33e-2)" "unprognostic (2.15e-2)" "unprognostic (1.04e-3)" "unprognostic (2.82e-2)" "unprognostic (2.69e-2)" "unprognostic (1.80e-2)" "potential prognostic unfavorable (1.68e-4)" "unprognostic (2.46e-2)" "unprognostic (1.12e-2)" "unprognostic (1.14e-1)" "unprognostic (2.91e-1)" "unprognostic (1.18e-3)" "unprognostic (9.68e-2)" "unprognostic (5.84e-2)" "unprognostic (1.26e-2)" "unprognostic (1.47e-1)" "unprognostic (2.18e-1)" "unprognostic (1.66e-1)" "unprognostic (5.60e-3)" "unprognostic (6.10e-2)" GRHPR "GLXR, PH2" ENSG00000137106 "Glyoxylate and hydroxypyruvate reductase" Q9UBQ7 9 37422666-37436990 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 610.0" "Cell type enriched" "Detected in all" 5 "Hepatocytes: 1048.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022971, HPA078575" Enhanced Approved Nucleoplasm,Cytosol NA NA 3600000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 55: Lymphoma - Immune response" "Cluster 93: Hepatocytes - Bile production & excretion" 7 Cytosol Nucleoplasm "HPA022971: , HPA078575: " "potential prognostic unfavorable (7.83e-5)" "unprognostic (1.90e-2)" "unprognostic (6.71e-2)" "unprognostic (3.10e-1)" "unprognostic (6.13e-2)" "unprognostic (2.48e-2)" "unprognostic (5.82e-3)" "unprognostic (5.61e-3)" "unprognostic (1.29e-1)" "unprognostic (7.84e-2)" "potential prognostic favorable (1.09e-8)" "unprognostic (1.26e-2)" "unprognostic (1.22e-2)" "unprognostic (4.94e-3)" "potential prognostic favorable (2.00e-4)" "unprognostic (1.87e-2)" "unprognostic (2.27e-2)" "unprognostic (3.01e-1)" "unprognostic (1.16e-1)" "unprognostic (4.70e-1)" "unprognostic (9.37e-2)" "unprognostic (9.24e-2)" "unprognostic (1.05e-1)" "unprognostic (3.66e-1)" "unprognostic (2.32e-1)" "unprognostic (8.71e-2)" "unprognostic (4.54e-1)" "unprognostic (6.97e-2)" "unprognostic (2.00e-1)" "unprognostic (1.55e-1)" "unprognostic (1.92e-2)" GRIA1 "GluA1, GLUR1, GLURA" ENSG00000155511 "Glutamate ionotropic receptor AMPA type subunit 1" P42261 5 153489615-153813869 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 54.8;retina: 29.4" "Cell type enriched" "Detected in many" 4 "Bergmann glia: 3894.3" "Cell type enhanced" "Detected in all" "Bergmann glia: 3812.0;hippocampal CA4: 4632.2" "Cancer enriched" "Detected in some" 16 "Glioblastoma Multiforme (TCGA): 23.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney cancer: 6.7" "Adrenal gland - Adrenal medulla cells, Lung - Fibroblasts_1, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Stomach - Fibroblasts, Testis - Early spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035202 Enhanced NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 29: Forebrain - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" 14 "HPA035202: " "unprognostic (2.81e-1)" "unprognostic (5.78e-2)" "unprognostic (1.87e-1)" "unprognostic (9.65e-2)" "unprognostic (9.28e-2)" GRIA2 "GluA2, GLUR2, GLURB" ENSG00000120251 "Glutamate ionotropic receptor AMPA type subunit 2" P42262 4 157204182-157387146 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Autism spectrum disorder, Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 78.8" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 244.6;Astrocytes: 387.7;Bergmann glia: 509.2;Brain excitatory neurons: 980.2;Brain inhibitory neurons: 827.5;Corticotrophs: 517.9;Lactotrophs: 491.6;Oligodendrocyte progenitor cells: 1251.1;Oligodendrocytes: 573.1;Other brain neurons: 450.1;Retinal amacrine cells: 352.8;Retinal bipolar cells: 302.4;Retinal ganglion cells: 301.3;Somatotrophs: 520.9;Thyrotrophs: 725.5" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in some" 14 "Breast Invasive Carcinoma (TCGA): 10.1;Glioblastoma Multiforme (TCGA): 25.4;Uterine Corpus Endometrial Carcinoma (TCGA): 7.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 5.4;Rhabdoid: 11.3" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Alpha cells, Pancreas - Beta cells, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008441 Enhanced NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" 16 "HPA008441: " "unprognostic (7.95e-2)" "unprognostic (9.13e-2)" "unprognostic (6.55e-2)" "unprognostic (1.55e-2)" "unprognostic (1.90e-3)" "unprognostic (1.77e-1)" "unprognostic (1.88e-1)" "unprognostic (4.17e-3)" "unprognostic (2.13e-3)" GRIA3 "GluA3, GLUR3, GLURC, MRX94" ENSG00000125675 "Glutamate ionotropic receptor AMPA type subunit 3" P42263 X 123184153-123490915 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 38.9;retina: 15.5" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 155.1;Brain excitatory neurons: 441.7;Brain inhibitory neurons: 517.2;Oligodendrocyte progenitor cells: 499.3;Oligodendrocytes: 155.1;Other brain neurons: 201.7;Pancreatic islet cells: 266.5;Retinal amacrine cells: 289.3;Retinal ganglion cells: 216.3;Retinal horizontal cells: 1051.8" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in some" 7 "Glioblastoma Multiforme (TCGA): 22.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Brain cancer: 2.9;liver cancer: 4.0;Neuroblastoma: 3.0;thyroid cancer: 3.0" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Fibroblasts_2, Pancreas - Alpha cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058659, HPA073344" Enhanced "Intracellular and membrane" Receptor NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" 2 "HPA058659: , HPA073344: " "unprognostic (9.14e-3)" "unprognostic (3.95e-1)" "unprognostic (4.12e-2)" "unprognostic (3.14e-2)" "potential prognostic favorable (2.32e-4)" "unprognostic (1.14e-1)" "unprognostic (2.27e-1)" "unprognostic (3.56e-2)" "unprognostic (1.14e-2)" "unprognostic (9.45e-3)" "unprognostic (1.95e-1)" GRIA4 "GluA4, GLUR4, GLURD" ENSG00000152578 "Glutamate ionotropic receptor AMPA type subunit 4" P48058 11 105609535-105982090 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 60.3;retina: 28.6" "Cell type enhanced" "Detected in many" "Bergmann glia: 3016.8;Brain excitatory neurons: 828.9;Brain inhibitory neurons: 847.4;Corticotrophs: 901.0;Müller glia: 746.0;Oligodendrocyte progenitor cells: 1662.3;Oligodendrocytes: 549.2;Other brain neurons: 628.8;Retinal amacrine cells: 1460.9;Retinal ganglion cells: 718.5;Retinal horizontal cells: 3447.8" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in some" 8 "Glioblastoma Multiforme (TCGA): 24.0;Kidney Renal Clear Cell Carcinoma (TCGA): 7.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Neuroblastoma: 9.9;Rhabdoid: 9.5" "Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Corticotropes, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063282 Uncertain "Focal adhesion sites" "Intracellular and membrane" Receptor NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 2: Neurons - Nucleosome" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 6 "Focal adhesion sites" "HPA063282: " "unprognostic (2.98e-1)" "unprognostic (6.10e-3)" "unprognostic (5.12e-3)" "unprognostic (1.05e-3)" "potential prognostic favorable (2.35e-4)" "unprognostic (1.44e-2)" GRID1 "GluD1, KIAA1220" ENSG00000182771 "Glutamate ionotropic receptor delta type subunit 1" Q9ULK0 10 85599552-86366795 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.5" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 170.2;Astrocytes: 320.6;Bergmann glia: 597.8;Brain excitatory neurons: 241.9;Brain inhibitory neurons: 471.1;Oligodendrocyte progenitor cells: 588.0;Oligodendrocytes: 785.6;Other brain neurons: 241.9;Retinal amacrine cells: 185.6;Retinal bipolar cells: 401.1;Retinal ganglion cells: 173.8;Sertoli cells: 172.1" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Glioblastoma Multiforme (TCGA): 2.1;Thyroid Carcinoma (TCGA): 3.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Neuroblastoma: 2.5" "Breast - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 65: Brain - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 1 "unprognostic (4.44e-1)" "unprognostic (2.35e-1)" "potential prognostic favorable (6.22e-4)" "unprognostic (6.71e-3)" "unprognostic (1.79e-1)" "unprognostic (3.15e-1)" GRID2 "GluD2, GluR-delta-2" ENSG00000152208 "Glutamate ionotropic receptor delta type subunit 2" O43424 4 92303966-93810157 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" Neurodegeneration "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 10.5;testis: 31.7" "Cell type enriched" "Detected in many" 4 "Bergmann glia: 16983.7" "Group enriched" "Detected in all" 4 "Bergmann glia: 18167.2;cerebellar inhibitory: 19185.0" "Cancer enriched" "Detected in single" 6 "Glioblastoma Multiforme (TCGA): 5.1" "Region enhanced" "Detected in many" "cerebellum: 88.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enteroendocrine cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 99.3" "HPA056253, HPA058538" Enhanced NA NA "Cluster 67: Testis - Mixed function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" 3 "HPA056253: , HPA058538: " "unprognostic (1.70e-2)" "potential prognostic favorable (1.60e-5)" GRID2IP ENSG00000215045 "Grid2 interacting protein" A4D2P6 7 6496778-6551461 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 2.4" "Cell type enhanced" "Detected in many" "Epicardial cells: 20.5;Gonadotrophs: 22.0;Retinal ganglion cells: 19.3;Tuft cells: 46.1" "Cell type enriched" "Detected in many" 5 "thalamic excitatory: 60.1" "Low cancer specificity" "Detected in single" "Region enhanced" "Detected in all" "thalamus: 72.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Leukemia: 2.5" "Adrenal gland - Adrenal cortex cells" "Group enriched" "Detected in many" 5 "cerebellum: 22.4;thalamus: 7.2" "Low region specificity" "Detected in all" HPA045381 Approved "Plasma membrane" NA NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 38: Sub-cortical - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" 1 "Plasma membrane" "HPA045381: " "unprognostic (2.44e-1)" "unprognostic (1.45e-1)" "unprognostic (1.15e-1)" "unprognostic (1.48e-1)" GRIFIN ENSG00000275572 "Galectin-related inter-fiber protein" A4D1Z8 7 2474728-2476894 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Early spermatids: 1.0" "Cell type enriched" "Detected in single" 18 "astrocyte: 1.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 19: Astrocytes - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 28: Astrocytes - Homeostasis & neuron support" GRIK1 "GluK1, GLUR5" ENSG00000171189 "Glutamate ionotropic receptor kainate type subunit 1" P39086 21 29536933-29940033 "FDA approved drug targets, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "adrenal gland: 11.8;brain: 10.5;retina: 36.4" "Group enriched" "Detected in many" 8 "Adrenal medulla cells: 1297.7;Brain inhibitory neurons: 1598.6;Oligodendrocyte progenitor cells: 1553.2;Retinal bipolar cells: 2905.6" "Cell type enhanced" "Detected in all" "lower rhombic lip: 3228.1;MGE interneuron: 3708.2;midbrain-derived inhibitory: 8188.5" "Cancer enriched" "Detected in some" 5 "Glioblastoma Multiforme (TCGA): 9.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adrenal gland - Adrenal medulla cells, Breast - Breast glandular cells, Stomach - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014623, HPA073879" Uncertain Supported "Vesicles,Plasma membrane" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 49: Hindbrain - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 3 "Plasma membrane" Vesicles "HPA014623: , HPA073879: " "unprognostic (2.10e-1)" "unprognostic (1.08e-3)" "unprognostic (3.99e-3)" "unprognostic (4.72e-3)" GRIK2 "GluK2, GLUR6, MRT6" ENSG00000164418 "Glutamate ionotropic receptor kainate type subunit 2" Q13002 6 100962701-102081622 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 10.0;heart muscle: 4.0" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 563.8;Brain excitatory neurons: 2424.8;Brain inhibitory neurons: 1884.8;Corticotrophs: 1125.5;Lactotrophs: 1101.3;Oligodendrocyte progenitor cells: 1616.2;Oligodendrocytes: 481.2;Other brain neurons: 1559.5;Schwann cells: 778.9;Tuft cells: 495.7" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 4 "Glioblastoma Multiforme (TCGA): 9.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 6.2;skin cancer: 8.4" "Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Kidney - Podocytes, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014395, HPA014623, CAB022463" Approved "Intracellular and membrane" Receptor NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 69: Skin cancer - ECM organization" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 5 "CAB022463: , HPA014395: , HPA014623: " "unprognostic (1.06e-1)" "unprognostic (6.01e-3)" "unprognostic (9.41e-2)" "unprognostic (1.57e-3)" "unprognostic (2.40e-3)" "unprognostic (7.87e-2)" "unprognostic (7.95e-2)" "unprognostic (1.02e-1)" "unprognostic (2.71e-2)" "unprognostic (2.25e-1)" "unprognostic (6.00e-2)" "unprognostic (2.09e-1)" "unprognostic (3.05e-3)" "unprognostic (3.37e-2)" GRIK3 "GluK3, GLUR7" ENSG00000163873 "Glutamate ionotropic receptor kainate type subunit 3" Q13003 1 36795527-37034515 "FDA approved drug targets, Plasma proteins, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.6;intestine: 7.4;pituitary gland: 8.6" "Cell type enriched" "Detected in some" 6 "Pituicytes/FSCs: 841.5" "Cell type enhanced" "Detected in many" "MGE interneuron: 365.1" "Cancer enriched" "Detected in some" 4 "Glioblastoma Multiforme (TCGA): 23.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 11.1;lung cancer: 9.2;Neuroblastoma: 7.0" "Adipose visceral - Smooth muscle cells, Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" "unprognostic (1.77e-1)" "unprognostic (1.18e-2)" "unprognostic (3.22e-1)" "unprognostic (5.68e-2)" "validated prognostic favorable (2.93e-5)" "validated prognostic favorable (4.06e-4)" "unprognostic (1.33e-1)" "unprognostic (1.36e-2)" "unprognostic (3.08e-1)" "unprognostic (2.84e-1)" GRIK4 "GluK4, GRIK, KA1" ENSG00000149403 "Glutamate ionotropic receptor kainate type subunit 4" Q16099 11 120511746-120988906 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.3" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 117.0;Astrocytes: 128.6;Bergmann glia: 398.1;Brain excitatory neurons: 134.9;Cone photoreceptor cells: 225.6;Ependymal cells: 321.1;Gonadotrophs: 147.7;Myosatellite cells: 104.9;Oligodendrocyte progenitor cells: 285.5;Oligodendrocytes: 115.8;Other brain neurons: 147.8;Pituicytes/FSCs: 142.7;Retinal ganglion cells: 96.6;Thyrotrophs: 144.4" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in some" 6 "Glioblastoma Multiforme (TCGA): 6.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Myeloma: 4.2" "Kidney - Fibroblasts, Lung - Fibroblasts_1, Pituitary gland - Undifferentiated cells (Pituitary gland), Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074453 Enhanced NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 51: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 35: Neurons - Synaptic function & neurogenesis" "HPA074453: " "unprognostic (1.06e-1)" "unprognostic (1.91e-1)" "unprognostic (8.55e-3)" "unprognostic (6.96e-3)" GRIK5 "GluK5, GRIK2, KA2" ENSG00000105737 "Glutamate ionotropic receptor kainate type subunit 5" Q16478 19 41998321-42070206 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.5;testis: 31.4" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 53.2;Brain excitatory neurons: 66.0;Brain inhibitory neurons: 59.0;Choroid plexus epithelial cells: 49.4;Distal convoluted tubule cells: 44.5;Early primary spermatocytes: 43.6;Gonadotrophs: 49.6;Oligodendrocyte progenitor cells: 46.9;Other brain neurons: 50.1;Pituicytes/FSCs: 41.1;Retinal amacrine cells: 55.2;Retinal bipolar cells: 65.0;Retinal ganglion cells: 42.5;Retinal horizontal cells: 52.1;Rod photoreceptor cells: 73.9;Thyrotrophs: 52.3" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Glioblastoma Multiforme (TCGA): 35.3;Kidney Chromophobe (TCGA): 10.6;Ovary Serous Cystadenocarcinoma (TCGA): 11.9;Thyroid Carcinoma (TCGA): 11.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Leukemia: 9.9;Neuroblastoma: 19.3" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Breast - Breast glandular cells, Lung - Smooth muscle cells, Spleen - Fibroblasts_1, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074001 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 65: Brain - Transcription" "Cluster 29: Forebrain - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 35: Neurons - Synaptic function & neurogenesis" 2 "Plasma membrane" Nucleoplasm "HPA074001: " "unprognostic (9.31e-2)" "unprognostic (1.41e-1)" "unprognostic (1.94e-2)" "unprognostic (1.59e-1)" "unprognostic (5.06e-3)" "unprognostic (1.66e-1)" "unprognostic (8.59e-2)" "unprognostic (1.32e-3)" "unprognostic (8.04e-3)" "potential prognostic favorable (4.37e-4)" "unprognostic (1.06e-1)" "unprognostic (6.18e-2)" "unprognostic (1.44e-2)" "unprognostic (1.12e-1)" "unprognostic (3.87e-2)" "unprognostic (1.46e-1)" GRIN1 "GluN1, NMDAR1" ENSG00000176884 "Glutamate ionotropic receptor NMDA type subunit 1" Q05586 9 137138346-137168756 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 67 "brain: 215.2" "Group enriched" "Detected in some" 7 "Brain excitatory neurons: 182.1;Brain inhibitory neurons: 259.5;Other brain neurons: 119.0;Retinal amacrine cells: 129.2;Retinal ganglion cells: 88.8" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Glioblastoma Multiforme (TCGA): 4.6;Prostate Adenocarcinoma (TCGA): 1.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 4.9;prostate cancer: 2.5" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enteroendocrine cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067773 Enhanced NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" 11 "HPA067773: " "unprognostic (2.45e-1)" "unprognostic (1.98e-1)" "unprognostic (5.17e-2)" "unprognostic (2.05e-2)" "unprognostic (1.73e-1)" "unprognostic (9.92e-3)" GRIN2A "GluN2A, NMDAR2A" ENSG00000183454 "Glutamate ionotropic receptor NMDA type subunit 2A" Q12879 16 9753404-10182928 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Cancer-related genes, Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 15.1" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 785.7;Brain inhibitory neurons: 509.2;Ependymal cells: 474.4;Epicardial cells: 175.1;Müller glia: 113.5;Oligodendrocytes: 136.6;Retinal amacrine cells: 358.5;Retinal ganglion cells: 386.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Kidney Renal Clear Cell Carcinoma (TCGA): 2.0;Ovary Serous Cystadenocarcinoma (TCGA): 2.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022725, HPA050216" Enhanced Uncertain "Endoplasmic reticulum,Vesicles" NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 35: Neurons - Synaptic function & neurogenesis" 15 "Endoplasmic reticulum" Vesicles "CAB022725: , HPA050216: " "unprognostic (1.65e-1)" "unprognostic (1.02e-1)" "unprognostic (6.45e-2)" "unprognostic (2.26e-1)" "unprognostic (1.98e-2)" "unprognostic (1.78e-1)" "unprognostic (1.47e-1)" "unprognostic (4.28e-2)" GRIN2B "GluN2B, NMDAR2B" ENSG00000273079 "Glutamate ionotropic receptor NMDA type subunit 2B" Q13224 12 13437942-13982002 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 17 "brain: 6.8" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 677.9;Brain inhibitory neurons: 895.2;Oligodendrocyte progenitor cells: 253.8;Other brain neurons: 372.0;Pituitary stem cells: 97.1;Retinal amacrine cells: 169.6;Retinal ganglion cells: 104.3;Tuft cells: 184.5" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Colon Adenocarcinoma (TCGA): 1.1;Rectum Adenocarcinoma (TCGA): 1.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 1.5" "Adrenal gland - Adrenal medulla cells, Liver - Hepatocytes, Pituitary gland - Undifferentiated cells (Pituitary gland), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA052160, HPA069762" Approved Supported "Nucleoplasm,Plasma membrane,Primary cilium,Primary cilium tip,Primary cilium transition zone,Basal body" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 35: Neurons - Synaptic function & neurogenesis" 26 "Plasma membrane" "Nucleoplasm, Primary cilium, Primary cilium tip, Primary cilium transition zone, Basal body" "HPA052160: , HPA069762: " "unprognostic (1.63e-1)" "unprognostic (5.01e-2)" "unprognostic (9.12e-2)" "unprognostic (5.18e-2)" "unprognostic (1.15e-1)" GRIN2C "GluN2C, NMDAR2C" ENSG00000161509 "Glutamate ionotropic receptor NMDA type subunit 2C" Q14957 17 74842023-74861504 "FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 113.7" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 22.8;Astrocytes: 148.6;Bergmann glia: 57.7;Brain excitatory neurons: 32.4;Hofbauer cells: 42.5;Müller glia: 26.8;Retinal amacrine cells: 29.2;Retinal ganglion cells: 23.2;Sertoli cells: 33.1" "Cell type enhanced" "Detected in many" "astrocyte: 133.3;Bergmann glia: 60.7;upper rhombic lip: 99.1" "Cancer enhanced" "Detected in some" "Thyroid Carcinoma (TCGA): 6.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 14 "cerebellum: 53.4" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 37: Neurons - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 28: Astrocytes - Homeostasis & neuron support" 62 "unprognostic (1.19e-1)" "unprognostic (8.40e-2)" "unprognostic (1.30e-2)" "unprognostic (1.49e-1)" "unprognostic (1.85e-2)" "unprognostic (1.48e-2)" GRIN2D "EB11, GluN2D, NMDAR2D, NR2D" ENSG00000105464 "Glutamate ionotropic receptor NMDA type subunit 2D" O15399 19 48393668-48444931 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.1" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 28.8;Extravillous trophoblasts: 20.3;Hepatic stellate cells: 12.9;Oligodendrocyte progenitor cells: 30.1;Other brain neurons: 24.6;Retinal amacrine cells: 21.7;Retinal bipolar cells: 12.6;Rod photoreceptor cells: 15.1" "Cell type enhanced" "Detected in many" "CGE interneuron: 74.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB009006 Approved NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 109: Neurons - Neuronal signaling" "CAB009006: " "potential prognostic unfavorable (3.80e-4)" "unprognostic (8.20e-2)" "unprognostic (2.25e-1)" "unprognostic (4.50e-1)" "unprognostic (1.44e-1)" "unprognostic (1.08e-1)" "unprognostic (1.34e-1)" "unprognostic (3.89e-1)" "unprognostic (3.39e-1)" "potential prognostic unfavorable (7.71e-4)" "unprognostic (1.49e-1)" "unprognostic (2.21e-1)" "potential prognostic unfavorable (8.74e-5)" "unprognostic (9.08e-2)" "unprognostic (1.06e-1)" "unprognostic (9.50e-2)" "unprognostic (6.27e-3)" "unprognostic (2.95e-1)" "unprognostic (2.33e-2)" "unprognostic (8.32e-2)" "unprognostic (2.44e-1)" GRIN3A GluN3A ENSG00000198785 "Glutamate ionotropic receptor NMDA type subunit 3A" Q8TCU5 9 101569352-101738647 "FDA approved drug targets, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 7.1" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 49.3;Brain inhibitory neurons: 108.2;Epicardial cells: 13.6;Other brain neurons: 47.6;Prostatic glandular cells: 18.6;Retinal amacrine cells: 23.3" "Cell type enhanced" "Detected in all" "LAMP5-LHX6 and Chandelier: 410.7;MGE interneuron: 314.1" "Cancer enriched" "Detected in single" 7 "Prostate Adenocarcinoma (TCGA): 4.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 3.1;prostate cancer: 3.6" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 73: Brain - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 109: Neurons - Neuronal signaling" 3 "unprognostic (2.08e-1)" "unprognostic (2.36e-2)" "unprognostic (1.98e-1)" GRIN3B GluN3B ENSG00000116032 "Glutamate ionotropic receptor NMDA type subunit 3B" O60391 19 1000419-1009732 "FDA approved drug targets, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 2.6;lung: 1.4" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 16.9;Endometrial ciliated cells: 22.7;Ependymal cells: 13.2;Epicardial cells: 11.4;Epididymal efferent duct ciliated cells: 35.7;Fallopian tube ciliated cells: 65.5;Respiratory ciliated cells: 110.5" "Cell type enriched" "Detected in single" 19 "ependymal cell: 14.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells" "Region enhanced" "Detected in single" "pons and medulla: 1.6" "Region enriched" "Detected in single" 8 "spinal cord: 5.6" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 43: Hindbrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 107: Ciliated cells - Cilia assembly & function" 8 "unprognostic (1.72e-2)" "unprognostic (6.03e-2)" "unprognostic (2.63e-1)" "unprognostic (5.93e-2)" "unprognostic (9.78e-2)" GRINA "HNRGW, LFG1, NMDARA1, TMBIM3" ENSG00000178719 "Glutamate ionotropic receptor NMDA type subunit associated protein 1" Q7Z429 8 143990056-143993415 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 283.0;Hepatocytes: 227.7;Kupffer cells: 285.9;Late spermatids: 756.4;Neutrophils: 397.2;Syncytiotrophoblasts: 294.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Adrenal cortex cells, Heart muscle - Macrophages, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036980, HPA036981" Approved Approved "Nucleoli fibrillar center,Cytosol" NA Yes "Cluster 25: Non-specific - Unknown function" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 38: Sub-cortical - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 6 "Nucleoli fibrillar center" Cytosol "HPA036980: , HPA036981: " "unprognostic (4.51e-2)" "unprognostic (3.41e-3)" "unprognostic (2.05e-1)" "unprognostic (1.27e-3)" "unprognostic (9.48e-2)" "unprognostic (1.99e-2)" "unprognostic (1.16e-1)" "unprognostic (4.66e-2)" "unprognostic (2.14e-3)" "unprognostic (2.33e-1)" "unprognostic (3.57e-2)" "unprognostic (6.45e-2)" "unprognostic (1.55e-2)" "unprognostic (3.29e-2)" "unprognostic (6.59e-2)" "unprognostic (3.62e-2)" "unprognostic (7.41e-2)" "unprognostic (6.84e-2)" "unprognostic (1.61e-2)" "unprognostic (7.15e-2)" "unprognostic (8.99e-2)" "unprognostic (1.17e-1)" "unprognostic (1.32e-3)" "unprognostic (5.39e-2)" "unprognostic (3.27e-2)" "unprognostic (2.69e-1)" "unprognostic (3.42e-1)" "unprognostic (1.49e-1)" "unprognostic (1.89e-1)" "unprognostic (5.27e-2)" "unprognostic (5.74e-3)" GRIP1 ENSG00000155974 "Glutamate receptor interacting protein 1" Q9Y3R0 12 66347431-67069162 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 15.4" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 744.6;Brain inhibitory neurons: 1318.6;Lactotrophs: 769.9;Papillary tip epithelial cells: 833.7;Renal collecting duct intercalated cells: 1374.8;Renal collecting duct principal cells: 3017.4;Renal connecting tubule cells: 1419.6;Retinal amacrine cells: 1979.7;Retinal horizontal cells: 1037.7;Syncytiotrophoblasts: 964.9" "Cell type enhanced" "Detected in all" "LAMP5-LHX6 and Chandelier: 4821.4;MGE interneuron: 2856.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "myeloid DC: 4.8" "Lineage enriched" "Detected in many" 5 "dendritic cells: 4.8" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Pituitary gland - Lactotropes, Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038856 Uncertain NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 109: Neurons - Neuronal signaling" 30 "HPA038856: " "unprognostic (1.38e-1)" "unprognostic (4.54e-2)" "unprognostic (2.39e-1)" "unprognostic (1.08e-3)" "unprognostic (1.99e-1)" "unprognostic (3.92e-2)" "unprognostic (2.18e-3)" "unprognostic (1.43e-2)" "unprognostic (5.44e-2)" "unprognostic (2.12e-2)" "unprognostic (2.27e-1)" "unprognostic (7.72e-2)" "unprognostic (7.88e-3)" "unprognostic (1.44e-1)" "unprognostic (6.42e-2)" "unprognostic (1.57e-1)" "unprognostic (3.27e-3)" "unprognostic (8.51e-2)" "unprognostic (8.06e-2)" "unprognostic (8.22e-2)" "unprognostic (5.59e-2)" "unprognostic (3.61e-2)" "unprognostic (4.10e-2)" "unprognostic (2.95e-1)" "unprognostic (1.05e-1)" "unprognostic (1.71e-1)" "unprognostic (1.13e-2)" "unprognostic (1.12e-1)" GRIP2 KIAA1719 ENSG00000144596 "Glutamate receptor interacting protein 2" Q9C0E4 3 14489107-14556075 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "heart muscle: 12.4;skeletal muscle: 33.5;tongue: 11.6" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 79.0;Cardiomyocytes: 105.3;Myonuclei: 231.0;Other brain neurons: 30.2;Renal collecting duct intercalated cells: 60.5;Retinal amacrine cells: 58.6;Vascular smooth muscle cells: 87.5" "Cell type enhanced" "Detected in many" "MGE interneuron: 143.5;midbrain-derived inhibitory: 291.2;vascular associated smooth muscle cell: 177.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 5.0;Rhabdoid: 5.0" "Heart muscle - Cardiomyocytes, Prostate - Fibroblasts, Skeletal muscle - Skeletal myocytes, Stomach - Parietal cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA035673 Approved Cytosol NA NA "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 55: Myocytes - Oxidative muscle function" 1 Cytosol "HPA035673: " "unprognostic (2.52e-1)" "unprognostic (7.34e-2)" "unprognostic (1.57e-1)" "unprognostic (6.24e-3)" "unprognostic (1.56e-1)" "unprognostic (2.17e-1)" "unprognostic (1.90e-2)" "unprognostic (2.32e-1)" GRIPAP1 "DKFZp434P0630, GRASP-1, GRASP1, KIAA1167, MPMGp800B12492Q3" ENSG00000068400 "GRIP1 associated protein 1" Q4V328 X 48973720-49002265 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 136.6;Rod photoreceptor cells: 124.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000282, HPA000615" Approved Approved Vesicles,Cytosol NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 64: Non-specific - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 79: Photoreceptor cells - Phototransduction" 62 "Vesicles, Cytosol" "HPA000282: , HPA000615: " "unprognostic (2.37e-2)" "unprognostic (4.59e-3)" "unprognostic (1.53e-2)" "unprognostic (1.17e-1)" "unprognostic (5.28e-2)" "unprognostic (7.68e-3)" "unprognostic (5.07e-2)" "unprognostic (4.53e-3)" "unprognostic (4.60e-2)" "unprognostic (1.20e-1)" "potential prognostic favorable (7.18e-4)" "unprognostic (1.45e-1)" "unprognostic (2.35e-1)" "unprognostic (1.29e-2)" "unprognostic (3.82e-1)" "unprognostic (3.56e-1)" "unprognostic (2.93e-2)" "unprognostic (1.50e-1)" "unprognostic (1.41e-1)" "unprognostic (1.32e-1)" "unprognostic (3.31e-1)" "unprognostic (1.34e-2)" "unprognostic (5.80e-3)" "unprognostic (1.19e-1)" "unprognostic (4.72e-2)" "unprognostic (1.66e-1)" "unprognostic (9.38e-2)" "unprognostic (7.41e-2)" "unprognostic (1.37e-1)" "unprognostic (1.07e-1)" "unprognostic (2.50e-1)" GRK1 "GPRK1, RHOK, RK" ENSG00000185974 "G protein-coupled receptor kinase 1" Q15835 13 113667219-113737736 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" "Kinase, Serine/threonine-protein kinase, Transferase" "Congenital stationary night blindness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 48 "retina: 39.5" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 2.1;Rod photoreceptor cells: 2.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 12 "prostate cancer: 1.1" "Heart muscle - Cardiomyocytes, Stomach - Parietal cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035200, HPA059376" Enhanced Approved "Principal piece" NA NA "Cluster 42: Retina - Visual perception" "Cluster 60: Prostate cancer - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" "Principal piece" "HPA035200: , HPA059376: " GRK2 "ADRBK1, BARK1" ENSG00000173020 "G protein-coupled receptor kinase 2" P25098 11 67266473-67286556 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Kupffer cells: 122.0;Monocyte progenitors: 169.5;monocytes: 140.0;Neutrophil progenitors: 222.7;Neutrophils: 262.3" "Cell type enhanced" "Detected in all" "leukocyte: 131.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005021, CAB037248, HPA060707" Enhanced Approved "Golgi apparatus,Vesicles,Cytosol" NA NA 6800 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 39 Vesicles "Golgi apparatus, Cytosol" "CAB005021: , CAB037248: , HPA060707: " "unprognostic (2.91e-1)" "unprognostic (4.70e-2)" "unprognostic (3.53e-2)" "unprognostic (2.13e-1)" "unprognostic (6.71e-2)" "unprognostic (6.75e-2)" "unprognostic (6.29e-2)" "unprognostic (1.45e-2)" "unprognostic (1.93e-1)" "unprognostic (1.63e-1)" "unprognostic (2.90e-1)" "unprognostic (2.07e-1)" "unprognostic (5.02e-3)" "unprognostic (3.25e-1)" "unprognostic (1.74e-3)" "unprognostic (2.53e-2)" "unprognostic (8.14e-2)" "unprognostic (4.52e-3)" "unprognostic (1.85e-2)" "unprognostic (2.11e-1)" "unprognostic (3.11e-2)" "unprognostic (3.01e-2)" "unprognostic (3.08e-1)" "unprognostic (2.26e-1)" "unprognostic (2.22e-1)" "unprognostic (1.42e-1)" "unprognostic (4.98e-2)" "unprognostic (2.66e-1)" "unprognostic (1.31e-2)" GRK3 "ADRBK2, BARK2" ENSG00000100077 "G protein-coupled receptor kinase 3" P35626 22 25564675-25729294 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 19.8" "Cell type enhanced" "Detected in many" "Adipocytes: 987.4;B-cells: 311.8;cDC: 375.7;Macrophages: 315.6;Microglia: 315.8;monocytes: 338.4;Podocytes: 311.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "classical monocyte: 2.3;eosinophil: 2.4;intermediate monocyte: 3.8;memory B-cell: 2.4;myeloid DC: 1.7;naive B-cell: 2.8;non-classical monocyte: 4.3;plasmacytoid DC: 1.8" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Neuroblastoma: 38.9" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Colon enteroendocrine cells, Prostate - Prostate glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000804 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 51: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 89: Adipocytes - Lipid metabolism" 4 Nucleoplasm "Plasma membrane" "HPA000804: " "unprognostic (1.51e-1)" "unprognostic (1.70e-1)" "unprognostic (2.08e-1)" "unprognostic (1.17e-2)" "unprognostic (1.13e-1)" "unprognostic (9.93e-2)" "unprognostic (1.12e-3)" "unprognostic (2.83e-1)" "unprognostic (9.06e-3)" "unprognostic (1.06e-1)" "unprognostic (1.36e-1)" "unprognostic (1.33e-2)" "unprognostic (9.72e-2)" "unprognostic (2.98e-2)" "unprognostic (3.83e-1)" "unprognostic (2.01e-1)" "unprognostic (2.33e-2)" "unprognostic (1.84e-1)" "unprognostic (5.81e-2)" "unprognostic (4.26e-3)" "unprognostic (7.32e-3)" "unprognostic (8.77e-2)" "unprognostic (3.22e-2)" "unprognostic (8.09e-3)" "unprognostic (8.21e-2)" "unprognostic (1.94e-2)" "unprognostic (7.82e-3)" "unprognostic (2.00e-2)" "unprognostic (3.72e-2)" GRK4 "GPRK2L, GPRK4" ENSG00000125388 "G protein-coupled receptor kinase 4" P32298 4 2963571-3040760 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 39.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 219.4;Early primary spermatocytes: 182.6;Early spermatids: 371.1;Late primary spermatocytes: 432.2;Late spermatids: 753.9;Retinal ganglion cells: 173.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Pituitary gland - Somatotropes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA057023 Approved Approved "Plasma membrane,Cytosol,Calyx" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 67: Testis - Mixed function" "Cluster 35: Non-specific - DNA binding" "Cluster 7: Liver cancer - Metabolism" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 3 "Plasma membrane, Cytosol" Calyx "HPA057023: " "unprognostic (1.14e-1)" "potential prognostic unfavorable (2.48e-4)" "potential prognostic favorable (2.01e-4)" "unprognostic (3.08e-1)" "unprognostic (2.38e-1)" "unprognostic (5.05e-2)" "unprognostic (2.37e-1)" "unprognostic (1.67e-3)" "unprognostic (3.06e-1)" "unprognostic (1.42e-3)" "unprognostic (2.73e-1)" "unprognostic (3.14e-3)" "unprognostic (1.02e-2)" "unprognostic (2.88e-2)" "unprognostic (1.26e-1)" "unprognostic (1.31e-1)" "unprognostic (2.70e-3)" "unprognostic (2.87e-2)" "unprognostic (8.51e-2)" "unprognostic (2.17e-1)" "unprognostic (7.87e-2)" "potential prognostic favorable (4.56e-4)" "unprognostic (5.11e-2)" "unprognostic (5.12e-2)" "unprognostic (4.41e-1)" "unprognostic (3.36e-2)" "unprognostic (2.07e-1)" "unprognostic (3.02e-2)" "unprognostic (1.33e-1)" "unprognostic (9.24e-2)" "unprognostic (1.74e-1)" GRK5 GPRK5 ENSG00000198873 "G protein-coupled receptor kinase 5" P34947 10 119207571-119459745 "Enzymes, Predicted intracellular proteins" "Apoptosis, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 295.4;B-cells: 252.1;Fibro-adipogenic progenitors: 466.1;Fibroblasts: 242.9;Hepatic stellate cells: 322.7;Pericytes: 448.2;Podocytes: 420.4;Tuft cells: 726.3;Vascular endothelial cells: 272.8;Vascular smooth muscle cells: 246.4" "Cell type enhanced" "Detected in all" "pericyte: 461.8;vascular associated smooth muscle cell: 461.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells, Minor Salivary Gland - Endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025579, HPA046838" Approved Supported "Nuclear membrane,Nuclear speckles,Plasma membrane" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 4 "Nuclear membrane, Nuclear speckles" "Plasma membrane" "CAB025579: , HPA046838: " "unprognostic (5.34e-2)" "unprognostic (1.74e-2)" "unprognostic (2.48e-2)" "unprognostic (1.20e-1)" "unprognostic (3.32e-1)" "potential prognostic unfavorable (2.36e-4)" "unprognostic (1.65e-1)" "unprognostic (2.02e-2)" "unprognostic (9.99e-2)" "unprognostic (4.81e-2)" "unprognostic (1.59e-3)" "potential prognostic favorable (6.97e-5)" "potential prognostic unfavorable (9.27e-4)" "unprognostic (2.98e-2)" "unprognostic (8.99e-2)" "unprognostic (1.51e-1)" "unprognostic (2.21e-1)" "unprognostic (2.85e-2)" "unprognostic (3.51e-1)" "unprognostic (1.63e-2)" "unprognostic (4.45e-1)" "unprognostic (2.01e-1)" "unprognostic (4.15e-2)" "unprognostic (3.07e-1)" "unprognostic (1.03e-1)" "unprognostic (3.26e-1)" "unprognostic (1.61e-1)" "unprognostic (1.92e-1)" "unprognostic (2.51e-3)" "unprognostic (1.22e-1)" GRK6 GPRK6 ENSG00000198055 "G protein-coupled receptor kinase 6" P43250 5 177403204-177442901 "Enzymes, Predicted intracellular proteins" "Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 126.6" "Cell type enhanced" "Detected in many" "Late spermatids: 139.4;Megakaryocytes: 98.9;Neutrophil progenitors: 113.3;Neutrophils: 164.2;Plasma cells: 81.3;Platelets: 79.0" "Cell type enhanced" "Detected in all" "leukocyte: 44.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Neutrophils_2, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015327, HPA018903" Approved Approved Mitochondria NA NA 35000 "Cluster 25: Non-specific - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 34: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 12 Mitochondria "HPA015327: , HPA018903: " "unprognostic (3.90e-2)" "unprognostic (1.45e-1)" "unprognostic (2.80e-1)" "unprognostic (1.25e-1)" "unprognostic (9.43e-2)" "unprognostic (9.49e-2)" "unprognostic (2.21e-2)" "unprognostic (1.22e-1)" "unprognostic (2.19e-1)" "potential prognostic unfavorable (5.47e-4)" "unprognostic (3.93e-2)" "unprognostic (2.81e-2)" "unprognostic (4.26e-2)" "validated prognostic unfavorable (9.30e-7)" "validated prognostic unfavorable (4.12e-5)" "unprognostic (5.57e-2)" "unprognostic (1.47e-1)" "unprognostic (3.39e-2)" "unprognostic (1.53e-1)" "unprognostic (3.25e-1)" "unprognostic (1.41e-2)" "unprognostic (1.48e-3)" "unprognostic (3.48e-2)" "unprognostic (1.04e-2)" "unprognostic (1.73e-2)" "unprognostic (3.02e-2)" "unprognostic (1.44e-1)" "unprognostic (9.47e-3)" "unprognostic (3.02e-2)" "unprognostic (1.73e-2)" "unprognostic (1.17e-1)" GRK7 GPRK7 ENSG00000114124 "G protein-coupled receptor kinase 7" Q8WTQ7 3 141763408-141819352 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Sensory transduction, Vision" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 41 "retina: 10.4" "Cell type enriched" "Detected in some" 130 "Cone photoreceptor cells: 333.3" "Cell type enhanced" "Detected in some" "ependymal cell: 1.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "HPA075093, HPA078232" Enhanced Approved "Golgi apparatus" NA NA "Cluster 42: Retina - Visual perception" "Cluster 15: Non-specific - Transcription" "Cluster 79: Photoreceptor cells - Phototransduction" 4 "Golgi apparatus" "HPA075093: , HPA078232: " GRM1 "GPRC1A, mGlu1, MGLUR1, PPP1R85" ENSG00000152822 "Glutamate metabotropic receptor 1" Q13255 6 146027646-146437601 "Disease related genes, G-protein coupled receptors, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 16.0;retina: 5.1" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 529.4;Brain inhibitory neurons: 328.5;Other brain neurons: 98.6;Retinal amacrine cells: 84.6;Retinal ganglion cells: 131.3;Rod photoreceptor cells: 392.7" "Cell type enhanced" "Detected in all" "cerebellar inhibitory: 2095.7;hippocampal dentate gyrus: 1515.5" "Cancer enriched" "Detected in single" 6 "Kidney Chromophobe (TCGA): 3.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Kidney - Ascending Loop of Henle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015701 Approved Supported Approved Vesicles NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 15: Non-specific - Transcription" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 35: Neurons - Synaptic function & neurogenesis" 5 Vesicles "HPA015701: " "unprognostic (2.73e-3)" "unprognostic (2.80e-2)" GRM2 "GPRC1B, mGlu2, MGLUR2" ENSG00000164082 "Glutamate metabotropic receptor 2" Q14416 3 51707068-51718613 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "brain: 4.6" "Group enriched" "Detected in some" 4 "Brain excitatory neurons: 12.7;Cone photoreceptor cells: 4.1;Early primary spermatocytes: 3.4;Other brain neurons: 5.1;Retinal amacrine cells: 9.7" "Cell type enhanced" "Detected in many" "hippocampal dentate gyrus: 33.9" "Cancer enriched" "Detected in single" 5 "Testicular Germ Cell Tumor (TCGA): 1.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Bone cancer: 2.8" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027868, HPA065166" Approved Supported NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 24: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" 25 "HPA027868: , HPA065166: " "unprognostic (5.75e-1)" "unprognostic (1.68e-1)" GRM3 "GPRC1C, mGlu3, MGLUR3" ENSG00000198822 "Glutamate metabotropic receptor 3" Q14832 7 86643909-86864879 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 28 "brain: 48.9" "Group enriched" "Detected in many" 6 "Astrocytes: 512.8;Bergmann glia: 1329.2;Brain inhibitory neurons: 377.2;Oligodendrocytes: 1031.3" "Cell type enhanced" "Detected in all" "pericyte: 3059.1" "Group enriched" "Detected in some" 9 "Glioblastoma Multiforme (TCGA): 5.3;Kidney Chromophobe (TCGA): 2.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Myeloma: 1.3" "Lung - Alveolar cells type 2, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" Receptor NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 11: White matter - Signal transduction" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 35: Neurons - Synaptic function & neurogenesis" 6 "unprognostic (1.05e-1)" "unprognostic (3.78e-1)" "unprognostic (2.08e-1)" GRM4 "GPRC1D, mGlu4, MGLUR4" ENSG00000124493 "Glutamate metabotropic receptor 4" Q14833 6 34018643-34155622 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 334 "brain: 254.0" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 163.6;Brain inhibitory neurons: 44.3;Pancreatic islet cells: 47.9;Retinal amacrine cells: 74.2;Retinal ganglion cells: 38.6;Somatotrophs: 19.4" "Cell type enhanced" "Detected in many" "deep-layer near-projecting: 165.8;upper rhombic lip: 493.8" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 7.5" "Region enriched" "Detected in all" 7 "cerebellum: 171.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 1.3" "Pancreas - Alpha cells, Pancreas - Beta cells" "Region enhanced" "Detected in all" "cerebellum: 79.1" "Region enriched" "Detected in all" 5 "cerebellum: 178.6" CAB022096 Enhanced NA NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 2: Cerebellar granular cells - Neuronal signaling" "CAB022096: " "unprognostic (1.65e-1)" "unprognostic (3.22e-1)" "unprognostic (4.67e-1)" "unprognostic (3.81e-2)" "unprognostic (1.05e-1)" "unprognostic (9.01e-2)" GRM5 "GPRC1E, mGlu5, MGLUR5, PPP1R86" ENSG00000168959 "Glutamate metabotropic receptor 5" P41594 11 88504576-89065982 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 13.9" "Cell type enhanced" "Detected in many" "Bergmann glia: 929.7;Brain excitatory neurons: 870.3;Brain inhibitory neurons: 1299.0;Early spermatids: 267.4;Endometrial ciliated cells: 230.1;Gonadotrophs: 304.4;Lactotrophs: 291.9;Oligodendrocyte progenitor cells: 1160.3;Other brain neurons: 430.4;Retinal amacrine cells: 220.1;Retinal bipolar cells: 713.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Kidney Renal Papillary Cell Carcinoma (TCGA): 2.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "Gallbladder cancer: 2.6" "Lung - Respiratory ciliated cells, Pituitary gland - Lactotropes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" Receptor NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" 3 "unprognostic (7.68e-2)" "unprognostic (4.36e-2)" "unprognostic (3.01e-3)" GRM6 "CSNB1B, GPRC1F, mGlu6, MGLUR6" ENSG00000113262 "Glutamate metabotropic receptor 6" O15303 5 178977587-178996206 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Sensory transduction, Vision" "G-protein coupled receptor, Receptor, Transducer" "Congenital stationary night blindness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 118 "retina: 39.6" "Cell type enriched" "Detected in some" 35 "Retinal bipolar cells: 436.4" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "Brain cancer: 1.2" "Colon - Enteric glia cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA014511 Enhanced NA NA "Cluster 42: Retina - Visual perception" "Cluster 37: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "HPA014511: " GRM7 "GLUR7, GPRC1G, mGlu7, MGLUR7, PPP1R87" ENSG00000196277 "Glutamate metabotropic receptor 7" Q14831 3 6770001-7741533 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Cardiomyopathy, Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.3;parathyroid gland: 4.0" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 1138.1;Brain excitatory neurons: 1036.8;Brain inhibitory neurons: 1029.7;Oligodendrocyte progenitor cells: 1533.4;Other brain neurons: 753.5;Respiratory ciliated cells: 276.1;Retinal amacrine cells: 909.6;Retinal bipolar cells: 816.5" "Cell type enhanced" "Detected in all" "mammillary body: 3463.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adrenal gland - Adrenal medulla cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015964 Uncertain Cytosol NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 40: Non-specific - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" 2 Cytosol "HPA015964: " "unprognostic (1.88e-2)" GRM8 "GLUR8, GPRC1H, mGlu8, MGLUR8" ENSG00000179603 "Glutamate metabotropic receptor 8" O00222 7 126438598-127253093 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "choroid plexus: 20.4" "Cell type enriched" "Detected in many" 4 "Choroid plexus epithelial cells: 5167.3" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 4988.7;pericyte: 2109.3" "Group enriched" "Detected in some" 5 "Colon Adenocarcinoma (TCGA): 5.8;Glioblastoma Multiforme (TCGA): 1.6;Kidney Renal Clear Cell Carcinoma (TCGA): 3.8;Kidney Renal Papillary Cell Carcinoma (TCGA): 3.8;Rectum Adenocarcinoma (TCGA): 6.5" "Region enriched" "Detected in all" 4 "choroid plexus: 103.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Neuroblastoma: 6.5" "Adrenal gland - Adrenal medulla cells, Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051481 Uncertain NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 101: Choroid plexus epithelial cells - Ion transport" "HPA051481: " "unprognostic (1.42e-1)" "unprognostic (2.81e-1)" "unprognostic (2.08e-2)" "unprognostic (2.90e-1)" "unprognostic (1.13e-2)" "potential prognostic favorable (5.27e-4)" "unprognostic (1.66e-3)" "unprognostic (2.06e-1)" "unprognostic (1.02e-3)" "unprognostic (3.11e-2)" "unprognostic (9.43e-2)" GRN "CLN11, PCDGF, PGRN" ENSG00000030582 "Granulin precursor" P28799 17 44345246-44353106 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 1739.0;Esophageal suprabasal cells: 1204.5;Hofbauer cells: 975.8;Kupffer cells: 1058.7;Macrophages: 634.7;monocytes: 648.4;Syncytiotrophoblasts: 800.5" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 109.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "classical monocyte: 2059.0;intermediate monocyte: 1123.1;myeloid DC: 1535.9;neutrophil: 854.4;non-classical monocyte: 550.5;plasmacytoid DC: 1334.2" "Group enriched" "Detected in all" 8 "dendritic cells: 1535.9;granulocytes: 854.4;monocytes: 2059.0" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Lung - Macrophages, Minor Salivary Gland - Mitotic cells (Minor salivary gland), Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008763, CAB019394, HPA028747" Uncertain Enhanced Endosomes,Lysosomes "Secreted to blood" Cytokine NA NA 138000000 35000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 27: Breast cancer - Unknown function" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 233 Lysosomes Endosomes "CAB019394: , HPA008763: , HPA028747: " "unprognostic (3.89e-2)" "unprognostic (8.10e-2)" "unprognostic (8.46e-2)" "unprognostic (1.57e-1)" "unprognostic (2.33e-1)" "unprognostic (2.58e-1)" "unprognostic (1.87e-3)" "unprognostic (7.71e-3)" "unprognostic (1.37e-2)" "unprognostic (9.42e-2)" "unprognostic (3.48e-3)" "unprognostic (8.24e-2)" "unprognostic (9.12e-3)" "unprognostic (2.55e-3)" "unprognostic (1.15e-2)" "unprognostic (1.05e-1)" "unprognostic (3.57e-1)" "unprognostic (2.56e-2)" "unprognostic (1.43e-1)" "unprognostic (1.23e-1)" "unprognostic (1.38e-2)" "unprognostic (6.56e-2)" "unprognostic (9.70e-2)" "unprognostic (3.01e-1)" "unprognostic (1.56e-3)" "unprognostic (2.43e-2)" "unprognostic (2.90e-1)" "unprognostic (9.14e-2)" "unprognostic (9.58e-2)" "unprognostic (1.21e-2)" "unprognostic (1.35e-1)" GRP ENSG00000134443 "Gastrin releasing peptide" P07492 18 59220158-59230774 "Predicted intracellular proteins, Predicted secreted proteins" "Mast cell degranulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.4;lung: 8.5;stomach 1: 11.4" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 6.8;Breast myoepithelial cells: 8.6;Early spermatids: 12.1;Late primary spermatocytes: 14.7;Late spermatids: 16.7;Other brain neurons: 5.8;Respiratory ionocytes: 2.5;Vascular smooth muscle cells: 5.0" "Group enriched" "Detected in many" 4 "endothelial cell: 40.7;hippocampal dentate gyrus: 75.0" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 5 "midbrain: 56.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 26 "Bone cancer: 180.1;lung cancer: 47.9;thyroid cancer: 71.6" "Colon - Colon enteroendocrine cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Parafollicular cells" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "hippocampal formation: 33.2" "Secreted in other tissues" Other NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 35: Neurons - Synaptic function & neurogenesis" 1 "unprognostic (4.01e-1)" "unprognostic (6.00e-2)" "unprognostic (8.83e-2)" "unprognostic (1.29e-2)" "potential prognostic unfavorable (7.99e-4)" "unprognostic (1.84e-2)" "unprognostic (5.49e-3)" "unprognostic (1.47e-2)" "unprognostic (1.21e-1)" "unprognostic (1.96e-1)" "unprognostic (2.81e-1)" "unprognostic (3.52e-2)" "unprognostic (1.42e-1)" "unprognostic (8.09e-3)" "unprognostic (2.44e-1)" "unprognostic (4.27e-2)" "unprognostic (1.49e-1)" "unprognostic (2.56e-2)" "unprognostic (1.36e-1)" "potential prognostic unfavorable (5.84e-4)" "unprognostic (9.11e-2)" "unprognostic (2.41e-2)" "unprognostic (9.01e-3)" GRPEL1 "FLJ25609, GrpE, hMGE" ENSG00000109519 "GrpE like 1, mitochondrial" Q9HAV7 4 7058671-7068085 "Essential proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 279.4;Esophageal suprabasal cells: 170.9;Oocytes: 230.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036647 Supported Supported Nucleoplasm,Mitochondria NA NA 33000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 76: Non-specific - Metabolism" "Cluster 27: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 17: Non-specific - RNA processing" 22 Mitochondria Nucleoplasm "HPA036647: " "unprognostic (1.64e-1)" "potential prognostic unfavorable (3.25e-4)" "unprognostic (2.15e-1)" "unprognostic (2.81e-2)" "unprognostic (4.34e-2)" "unprognostic (1.21e-1)" "unprognostic (4.17e-2)" "unprognostic (1.73e-1)" "unprognostic (1.31e-3)" "unprognostic (5.58e-2)" "validated prognostic favorable (3.94e-4)" "validated prognostic favorable (4.60e-4)" "unprognostic (1.19e-2)" "unprognostic (1.24e-1)" "unprognostic (4.31e-2)" "potential prognostic unfavorable (1.99e-4)" "unprognostic (1.13e-3)" "unprognostic (7.88e-2)" "unprognostic (4.21e-1)" "unprognostic (1.16e-1)" "unprognostic (2.43e-1)" "unprognostic (3.26e-1)" "unprognostic (2.33e-1)" "unprognostic (5.86e-3)" "unprognostic (2.30e-3)" "unprognostic (3.83e-2)" "unprognostic (8.58e-2)" "unprognostic (3.61e-1)" "unprognostic (2.15e-1)" "unprognostic (2.16e-2)" "unprognostic (1.51e-2)" GRPEL2 "DKFZp451C205, FLJ23713, Mt-GrpE#2" ENSG00000164284 "GrpE like 2, mitochondrial" Q8TAA5 5 149345430-149354583 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 42.9" "Cell type enriched" "Detected in many" 45 "Esophageal apical cells: 1369.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Lung - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018173, HPA023211" Approved Enhanced Mitochondria NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 25: Non-specific - Transcription" "Cluster 13: Non-specific - Mixed function" "Cluster 84: Apical squamous epithelium - Cornification" 3 Mitochondria "HPA018173: , HPA023211: " "unprognostic (1.00e-2)" "unprognostic (3.04e-2)" "unprognostic (6.34e-2)" "unprognostic (1.42e-1)" "unprognostic (7.25e-3)" "unprognostic (2.25e-2)" "unprognostic (2.17e-2)" "potential prognostic unfavorable (4.29e-5)" "unprognostic (8.69e-2)" "unprognostic (1.02e-1)" "unprognostic (2.70e-3)" "unprognostic (6.48e-3)" "unprognostic (4.79e-2)" "potential prognostic unfavorable (4.86e-6)" "unprognostic (1.16e-3)" "unprognostic (1.68e-2)" "unprognostic (1.27e-1)" "unprognostic (1.93e-1)" "unprognostic (1.65e-1)" "unprognostic (2.11e-1)" "unprognostic (1.19e-1)" "unprognostic (1.75e-3)" "unprognostic (1.88e-3)" "unprognostic (8.45e-2)" "unprognostic (2.92e-3)" "unprognostic (1.09e-1)" "unprognostic (7.10e-2)" "unprognostic (2.80e-1)" "unprognostic (2.12e-1)" "unprognostic (7.86e-2)" "unprognostic (1.80e-1)" GRPR "BB2, BB2R, BRS2" ENSG00000126010 "Gastrin releasing peptide receptor" P30550 X 16123565-16153518 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "pancreas: 19.1" "Cell type enhanced" "Detected in some" "Brain inhibitory neurons: 3.1;Breast hormone-responsive cells: 3.0;Cone photoreceptor cells: 2.1;Neuroendocrine cells: 3.6;Oocytes: 13.8;Pancreatic acinar cells: 10.8;Retinal pigment epithelial cells: 4.3;Sertoli cells: 2.5;Thyrotrophs: 3.4" "Group enriched" "Detected in some" 7 "CGE interneuron: 19.2;LAMP5-LHX6 and Chandelier: 19.3;mammillary body: 7.0" "Cancer enriched" "Detected in some" 5 "Breast Invasive Carcinoma (TCGA): 11.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 12.1;Rhabdoid: 7.9" "Region enhanced" "Detected in single" "hypothalamus: 2.0" "Low region specificity" "Detected in all" HPA069604 Supported "Plasma membrane" NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 14: Neurons - Synaptic function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 109: Neurons - Neuronal signaling" "Plasma membrane" "HPA069604: " "unprognostic (8.22e-2)" "unprognostic (4.73e-1)" "unprognostic (1.45e-1)" "unprognostic (1.15e-1)" "unprognostic (1.19e-1)" "unprognostic (4.27e-1)" "unprognostic (8.23e-2)" "unprognostic (2.45e-1)" "unprognostic (1.92e-3)" "unprognostic (2.40e-1)" GRSF1 ENSG00000132463 "G-rich RNA sequence binding factor 1" Q12849 4 70815783-70839897 "Predicted intracellular proteins" "mRNA processing, tRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 242.1" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036984, HPA036985" Enhanced Enhanced Mitochondria NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 82: Dendritic cells - Antigen presentation" 175 Mitochondria "HPA036984: , HPA036985: " "unprognostic (1.22e-1)" "unprognostic (2.94e-3)" "unprognostic (1.03e-1)" "unprognostic (7.81e-2)" "potential prognostic favorable (4.17e-5)" "unprognostic (4.46e-2)" "unprognostic (8.52e-2)" "unprognostic (6.85e-2)" "unprognostic (6.23e-3)" "unprognostic (2.65e-3)" "potential prognostic favorable (1.39e-7)" "unprognostic (2.76e-3)" "unprognostic (1.10e-2)" "potential prognostic unfavorable (7.13e-7)" "unprognostic (3.69e-2)" "potential prognostic unfavorable (7.28e-5)" "unprognostic (8.04e-3)" "unprognostic (5.52e-2)" "unprognostic (1.01e-1)" "unprognostic (8.77e-2)" "unprognostic (2.83e-3)" "unprognostic (1.75e-1)" "unprognostic (8.07e-2)" "unprognostic (9.51e-2)" "unprognostic (3.10e-2)" "unprognostic (3.12e-1)" "unprognostic (1.15e-1)" "unprognostic (2.08e-1)" "unprognostic (1.78e-1)" "unprognostic (1.69e-1)" "unprognostic (1.60e-1)" GRTP1 "FLJ22474, TBC1D6" ENSG00000139835 "Growth hormone regulated TBC protein 1" Q5TC63 13 113324163-113364148 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 77.9" "Cell type enhanced" "Detected in many" "Colonocytes: 117.1;Cone photoreceptor cells: 130.4;Enterocytes: 135.7;Paneth cells: 100.6;Rod photoreceptor cells: 119.5" "Cell type enhanced" "Detected in some" "astrocyte: 26.5;Bergmann glia: 25.9;choroid plexus epithelial cell: 27.0;ependymal cell: 22.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 2.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046201 Enhanced NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 12: Non-specific - Vasculature" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 79: Photoreceptor cells - Phototransduction" "HPA046201: " "unprognostic (3.34e-2)" "unprognostic (3.57e-1)" "unprognostic (8.03e-2)" "unprognostic (1.24e-1)" "unprognostic (9.37e-2)" "unprognostic (2.13e-1)" "unprognostic (4.04e-2)" "unprognostic (6.44e-3)" "unprognostic (9.31e-2)" "potential prognostic unfavorable (6.53e-5)" "potential prognostic favorable (3.62e-7)" "unprognostic (4.16e-2)" "potential prognostic favorable (5.17e-5)" "unprognostic (8.81e-2)" "unprognostic (8.31e-2)" "unprognostic (1.74e-2)" "unprognostic (2.27e-1)" "unprognostic (1.62e-1)" "unprognostic (1.27e-1)" "unprognostic (1.30e-1)" "unprognostic (3.61e-2)" "unprognostic (1.97e-2)" "unprognostic (1.71e-1)" "unprognostic (9.83e-3)" "unprognostic (8.81e-2)" "unprognostic (1.59e-1)" "unprognostic (2.47e-1)" "unprognostic (7.22e-3)" "unprognostic (8.51e-2)" "unprognostic (2.75e-1)" "unprognostic (2.19e-1)" GRWD1 "GRWD, RRB1, WDR28" ENSG00000105447 "Glutamate rich WD repeat containing 1" Q9BQ67 19 48445841-48457022 "Essential proteins, Predicted intracellular proteins" "DNA replication" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 59.7;Migrating cytotrophoblasts: 54.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042643, HPA055680" Approved Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim" No No "Cluster 30: Non-specific - DNA binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 47 "Nucleoli, Nucleoli rim" Nucleoplasm "HPA042643: , HPA055680: " "unprognostic (1.24e-1)" "unprognostic (8.75e-2)" "unprognostic (2.66e-2)" "unprognostic (3.66e-3)" "unprognostic (7.05e-2)" "unprognostic (8.51e-2)" "unprognostic (2.45e-1)" "unprognostic (2.20e-1)" "unprognostic (1.93e-2)" "unprognostic (3.04e-2)" "potential prognostic favorable (1.07e-6)" "unprognostic (2.00e-2)" "unprognostic (2.85e-1)" "unprognostic (6.20e-3)" "potential prognostic unfavorable (4.67e-4)" "potential prognostic unfavorable (2.12e-4)" "unprognostic (6.74e-2)" "unprognostic (1.15e-1)" "unprognostic (2.18e-1)" "unprognostic (6.47e-2)" "unprognostic (1.49e-1)" "unprognostic (6.21e-2)" "unprognostic (1.96e-1)" "unprognostic (1.63e-2)" "unprognostic (9.15e-2)" "unprognostic (4.66e-2)" "unprognostic (8.59e-3)" "unprognostic (1.86e-1)" "unprognostic (2.90e-1)" "unprognostic (9.88e-2)" "unprognostic (8.49e-2)" GRXCR1 "DFNB25, PPP1R88" ENSG00000215203 "Glutaredoxin and cysteine rich domain containing 1" A8MXD5 4 42892713-43030658 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hearing "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "seminal vesicle: 2.4" "Group enriched" "Detected in some" 5 "Granulosa cells: 29.2;Mesothelial cells: 11.5" "Low cell type specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA040824 Uncertain NA NA "Cluster 38: Non-specific - Basic cellular processes" "Cluster 11: Neuronal - Sensory perception" "Cluster 94: Gonadal somatic cells - Mixed function" 7 "HPA040824: " GRXCR2 DFNB101 ENSG00000204928 "Glutaredoxin and cysteine rich domain containing 2" A6NFK2 5 145858521-145937126 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hearing "Deafness, Non-syndromic deafness" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 4 "Cardiomyocytes: 150.6" "Cell type enhanced" "Detected in some" "MGE interneuron: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "cerebral cortex: 2.0;hippocampal formation: 6.9" HPA059421 Uncertain NA NA "Cluster 11: Neuronal - Sensory perception" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" "HPA059421: " GSAP "LOC54103, PION" ENSG00000186088 "Gamma-secretase activating protein" A4D1B5 7 77310751-77416349 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 247.5;Kupffer cells: 202.9;NK-cells: 285.0" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 272.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Spleen - B-cells (Spleen)" "Region enhanced" "Detected in all" "cerebellum: 15.5" "Low region specificity" "Detected in all" HPA023994 Approved Vesicles NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 21: Non-specific - Metabolism" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 1 Vesicles "HPA023994: " "unprognostic (1.34e-2)" "unprognostic (3.44e-2)" "unprognostic (1.33e-1)" "unprognostic (3.35e-2)" "unprognostic (7.60e-2)" "unprognostic (3.70e-2)" "potential prognostic unfavorable (4.25e-5)" "unprognostic (8.25e-3)" "unprognostic (3.33e-3)" "potential prognostic favorable (3.73e-4)" "unprognostic (7.96e-2)" "unprognostic (1.47e-3)" "unprognostic (1.17e-1)" "unprognostic (3.93e-2)" "unprognostic (1.59e-2)" "unprognostic (2.13e-2)" "unprognostic (7.92e-2)" "unprognostic (1.27e-1)" "unprognostic (2.46e-3)" "unprognostic (7.31e-2)" "unprognostic (2.95e-2)" "unprognostic (2.78e-1)" "unprognostic (1.59e-1)" "unprognostic (2.13e-2)" "unprognostic (1.87e-2)" "unprognostic (1.34e-1)" "unprognostic (2.72e-2)" "unprognostic (1.94e-1)" "unprognostic (2.05e-1)" GSC ENSG00000133937 "Goosecoid homeobox" P56915 14 94768223-94770113 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 4.0;breast: 7.1" "Cell type enhanced" "Detected in some" "Adipocytes: 4.2;Breast hormone-responsive cells: 1.7;Breast myoepithelial cells: 2.6;Epididymal basal cells: 2.9;Fibro-adipogenic progenitors: 2.9;Fibroblasts: 7.2;Gastric chief cells: 4.4;Oocytes: 4.6;Pancreatic duct cells: 2.4;Parietal cells: 1.8;Pericytes: 4.9;Prostatic club cells: 2.7;Undifferentiated spermatogonia: 1.8;Vascular smooth muscle cells: 2.3" "Cell type enriched" "Detected in single" 18 "fibroblast: 2.2" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "hypothalamus: 3.0" "Immune cell enriched" "Detected in single" 8 "gdT-cell: 3.7" "Lineage enriched" "Detected in single" 18 "T-cells: 3.7" "Low cancer specificity" "Detected in some" "Breast - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblasts_2" "Not detected" "Not detected" "Not detected" "Not detected" "CAB079923, CAB079924" Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 108: Fibroblasts - ECM organization" "Nucleoplasm, Nuclear speckles" "CAB079923: , CAB079924: " "unprognostic (6.58e-2)" "unprognostic (4.04e-3)" "unprognostic (1.70e-1)" "unprognostic (1.24e-1)" "unprognostic (2.48e-1)" "unprognostic (2.03e-1)" "unprognostic (1.13e-1)" "unprognostic (2.33e-1)" "unprognostic (1.22e-1)" "unprognostic (1.87e-1)" "unprognostic (3.62e-2)" "unprognostic (9.72e-2)" GSC2 GSCL ENSG00000063515 "Goosecoid homeobox 2" O15499 22 19146993-19150292 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 20 "retina: 1.0;testis: 3.5" "Group enriched" "Detected in some" 10 "Cone photoreceptor cells: 2.1;Differentiating spermatogonia: 2.0;Undifferentiated spermatogonia: 5.8" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 15 "midbrain: 1.2;pons: 2.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" HPA043011 Uncertain NA NA "Cluster 47: Testis - Mixed function" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 1: Neuronal - Visual perception" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 46 "HPA043011: " GSDMA "FLJ39120, GSDM, GSDM1" ENSG00000167914 "Gasdermin A" Q96QA5 17 39953263-39977768 "Essential proteins, Predicted intracellular proteins, Transporters" Necrosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "skin 1: 58.0" "Cell type enhanced" "Detected in some" "Colonocytes: 4.4;Epididymal principal cells: 8.6;Esophageal apical cells: 18.7;Kupffer cells: 17.4;Macrophages: 5.0;Paneth cells: 11.6;Retinal horizontal cells: 4.0;Retinal pigment epithelial cells: 8.5" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 11.6;Skin Cutaneous Melanoma (TCGA): 10.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 7 "granulocytes: 1.0;T-cells: 2.6" "Cancer enhanced" "Detected in some" "breast cancer: 3.9;colorectal cancer: 4.3" "Heart muscle - Macrophages, Skin - Keratinocyte (granular), Thyroid gland - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA023313, HPA064826" Enhanced Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA 1500000 "Cluster 37: Skin - Keratinization" "Cluster 48: Non-specific - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 27 "Plasma membrane, Cytosol" "Nucleoplasm, Nuclear bodies" "HPA023313: , HPA064826: " "unprognostic (1.06e-1)" "unprognostic (5.36e-2)" "unprognostic (1.54e-1)" "unprognostic (1.98e-1)" "unprognostic (1.00e-2)" "unprognostic (2.04e-1)" "unprognostic (1.23e-1)" "unprognostic (1.86e-1)" "unprognostic (3.76e-2)" "unprognostic (1.75e-2)" "unprognostic (4.03e-2)" "unprognostic (1.27e-1)" "unprognostic (1.12e-1)" "unprognostic (2.05e-1)" "unprognostic (3.14e-2)" "unprognostic (1.22e-1)" "unprognostic (1.69e-1)" "unprognostic (1.26e-1)" "unprognostic (5.20e-2)" "unprognostic (3.14e-2)" "unprognostic (5.13e-2)" "unprognostic (8.72e-2)" GSDMB "GSDML, PRO2521" ENSG00000073605 "Gasdermin B" Q8TAX9 17 39904595-39919854 "Predicted intracellular proteins, Transporters" "Cytolysis, Necrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 71.8;liver: 54.4;stomach 1: 44.7" "Cell type enhanced" "Detected in many" "Adipocytes: 68.0;Colonocytes: 62.2;Enterocytes: 181.3;Foveolar cells: 146.5;Goblet cells: 81.5;Paneth cells: 58.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Stomach - Gastric mucous cells" "Not detected" "Not detected" "CAB013681, HPA023925, HPA052407" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 11: T-cells - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 53: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 1: Enterocytes - Absorption and Digestion" Nucleoplasm Cytosol "CAB013681: , HPA023925: , HPA052407: " "unprognostic (1.84e-2)" "unprognostic (2.67e-1)" "unprognostic (1.02e-1)" "potential prognostic favorable (4.38e-6)" "unprognostic (5.88e-2)" "unprognostic (3.13e-1)" "unprognostic (1.98e-1)" "unprognostic (1.40e-3)" "unprognostic (2.55e-1)" "potential prognostic unfavorable (2.25e-11)" "unprognostic (3.21e-3)" "unprognostic (1.71e-1)" "unprognostic (1.49e-2)" "unprognostic (1.07e-1)" "unprognostic (1.63e-1)" "unprognostic (1.63e-2)" "unprognostic (1.40e-1)" "unprognostic (1.90e-2)" "unprognostic (2.53e-1)" "unprognostic (5.97e-3)" "unprognostic (1.64e-3)" "unprognostic (1.61e-1)" "unprognostic (3.53e-2)" "unprognostic (2.65e-1)" "unprognostic (5.57e-2)" "unprognostic (3.36e-1)" "unprognostic (1.87e-1)" "unprognostic (7.04e-2)" "unprognostic (2.44e-1)" GSDMC MLZE ENSG00000147697 "Gasdermin C" Q9BYG8 8 129748196-129786624 "Predicted intracellular proteins, Transporters" Necrosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 33.0;lymphoid tissue: 13.6;skin 1: 25.9;vagina: 12.4" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 4.5;Epicardial cells: 2.3;Esophageal apical cells: 5.3;Esophageal basal cells: 1.5;Esophageal suprabasal cells: 2.8;Ocular epithelial cells: 2.1;Papillary tip epithelial cells: 6.0;Suprabasal keratinocytes: 7.0" "Cell type enhanced" "Detected in single" "astrocyte: 2.9" "Cancer enhanced" "Detected in some" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 4.6;Head and Neck Squamous Cell Carcinoma (TCGA): 7.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 3.8;head and neck cancer: 3.2;pancreatic cancer: 2.2" "Heart muscle - Cardiomyocytes, Prostate - Urothelial cells, Skeletal muscle - Skeletal myocytes, Skin - Keratinocyte (other)" "Low region specificity" "Detected in many" "HPA026317, HPA072904" Supported Approved Vesicles NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 26: Keratinocytes - Keratinization" 1 Vesicles "HPA026317: , HPA072904: " "unprognostic (1.08e-1)" "unprognostic (2.60e-1)" "unprognostic (5.32e-3)" "unprognostic (6.72e-2)" "unprognostic (1.60e-1)" "unprognostic (4.97e-2)" "unprognostic (2.14e-2)" "unprognostic (3.26e-1)" "unprognostic (1.52e-1)" "unprognostic (2.47e-1)" "potential prognostic unfavorable (8.26e-5)" GSDMD "DF5L, FLJ12150, GSDMDC1" ENSG00000104518 "Gasdermin D" P57764 8 143553207-143563062 "Predicted intracellular proteins, Transporters" "Immunity, Inflammatory response, Innate immunity, Necrosis, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Foveolar cells: 28.7;Papillary tip epithelial cells: 25.4" "Group enriched" "Detected in many" 11 "astrocyte: 22.6;Bergmann glia: 19.0;central nervous system macrophage: 21.3;choroid plexus epithelial cell: 12.3;endothelial cell: 44.7;ependymal cell: 18.1;fibroblast: 16.2;leukocyte: 34.7;pericyte: 12.0;vascular associated smooth muscle cell: 14.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004656, HPA044487" Uncertain Supported Nucleoplasm "Intracellular and membrane" Transcription NA NA 14000 "Cluster 33: Non-specific - ATP binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 8: Immune cells - Immune response" "Cluster 35: RS4;11 - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 13 Nucleoplasm "CAB004656: , HPA044487: " "unprognostic (9.26e-2)" "unprognostic (1.10e-1)" "unprognostic (1.85e-1)" "unprognostic (7.99e-2)" "unprognostic (3.56e-2)" "unprognostic (4.21e-2)" "unprognostic (9.70e-2)" "unprognostic (4.04e-3)" "unprognostic (3.11e-1)" "unprognostic (2.31e-2)" "unprognostic (2.63e-2)" "unprognostic (2.55e-1)" "unprognostic (1.12e-2)" "unprognostic (1.56e-1)" "unprognostic (3.49e-1)" "unprognostic (4.52e-1)" "unprognostic (1.71e-1)" "unprognostic (3.14e-2)" "unprognostic (7.30e-2)" "unprognostic (5.80e-3)" "unprognostic (5.68e-3)" "unprognostic (1.00e-3)" "unprognostic (1.83e-2)" "unprognostic (2.06e-1)" "unprognostic (1.10e-2)" "unprognostic (1.25e-1)" "unprognostic (3.89e-2)" "unprognostic (3.42e-2)" "unprognostic (1.33e-1)" "unprognostic (3.69e-1)" "unprognostic (1.31e-1)" GSDME "DFNA5, ICERE-1" ENSG00000105928 "Gasdermin E" O60443 7 24698355-24757940 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" Necrosis "Deafness, Non-syndromic deafness, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bergmann glia: 82.9;Cytotrophoblasts: 213.4;Decidual stromal cells: 51.1;Distal convoluted tubule cells: 51.5;Enterocytes: 72.5;Epicardial cells: 104.6;Mesothelial cells: 57.4;Migrating cytotrophoblasts: 123.7;Oocytes: 128.9;Syncytiotrophoblasts: 115.6" "Cell type enhanced" "Detected in all" "Bergmann glia: 97.6" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 55.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory B-cell: 9.1;myeloid DC: 5.8;naive B-cell: 8.4" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Breast - Fibroblasts, Prostate - Smooth muscle cells, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011326, CAB019306" Approved Supported Cytosol NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 9 Cytosol "CAB019306: , HPA011326: " "unprognostic (1.08e-1)" "unprognostic (3.79e-1)" "unprognostic (3.96e-2)" "unprognostic (1.68e-2)" "unprognostic (3.52e-2)" "unprognostic (2.11e-2)" "potential prognostic unfavorable (8.69e-4)" "unprognostic (1.13e-2)" "unprognostic (1.20e-1)" "unprognostic (1.74e-3)" "unprognostic (5.45e-3)" "unprognostic (3.55e-2)" "potential prognostic unfavorable (2.84e-5)" "unprognostic (1.75e-1)" "unprognostic (2.68e-3)" "unprognostic (1.08e-1)" "unprognostic (9.06e-3)" "unprognostic (2.58e-2)" "unprognostic (6.27e-2)" "unprognostic (2.90e-1)" "unprognostic (6.56e-3)" "unprognostic (3.13e-1)" "unprognostic (1.03e-1)" "unprognostic (1.55e-2)" "unprognostic (2.47e-1)" "potential prognostic unfavorable (4.45e-5)" "unprognostic (8.39e-3)" "unprognostic (6.55e-2)" "unprognostic (1.07e-3)" GSE1 KIAA0182 ENSG00000131149 "Gse1 coiled-coil protein" Q14687 16 85169525-85676204 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 682.5;Sertoli cells: 519.5;Somatotrophs: 615.2;Syncytiotrophoblasts: 573.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036365, HPA042090" Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 2: Neurons - Nucleosome" "Cluster 54: Non-specific - Transcription" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 52 Mitochondria Nucleoplasm "HPA036365: , HPA042090: " "unprognostic (3.57e-2)" "unprognostic (4.75e-2)" "unprognostic (1.08e-2)" "unprognostic (4.56e-2)" "unprognostic (1.58e-1)" "unprognostic (1.92e-1)" "unprognostic (7.74e-3)" "unprognostic (3.86e-1)" "unprognostic (1.93e-1)" "potential prognostic favorable (5.01e-4)" "unprognostic (8.90e-2)" "unprognostic (8.13e-2)" "unprognostic (2.08e-1)" "unprognostic (1.48e-1)" "unprognostic (4.89e-2)" "unprognostic (4.08e-3)" "unprognostic (2.36e-1)" "unprognostic (2.94e-2)" "unprognostic (2.46e-1)" "unprognostic (3.91e-2)" "unprognostic (4.12e-3)" "unprognostic (2.85e-1)" "unprognostic (1.71e-2)" "unprognostic (1.36e-1)" "unprognostic (2.23e-1)" "unprognostic (4.94e-2)" "unprognostic (2.18e-1)" "unprognostic (6.85e-2)" "unprognostic (4.20e-2)" GSG1 MGC3146 ENSG00000111305 "Germ cell associated 1" Q2KHT4 12 13083532-13103683 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "testis: 406.3" "Cell type enriched" "Detected in some" 7 "Late spermatids: 19251.8" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in some" 5 "Kidney Renal Papillary Cell Carcinoma (TCGA): 4.3;Testicular Germ Cell Tumor (TCGA): 8.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 13 "Rhabdoid: 117.1" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 47: Testis - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 1 "unprognostic (1.42e-2)" "potential prognostic unfavorable (2.64e-6)" "unprognostic (5.48e-3)" "unprognostic (2.40e-1)" "unprognostic (7.57e-3)" "unprognostic (1.41e-2)" "unprognostic (7.55e-2)" "unprognostic (8.77e-3)" GSG1L "KTSR5831, MGC18079, PRO19651" ENSG00000169181 "GSG1 like" Q6UXU4 16 27787528-28063714 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "blood vessel: 18.1;brain: 19.8;heart muscle: 21.6" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 43.0;Brain inhibitory neurons: 88.0;Endometrial stromal cells: 30.0;Oligodendrocyte progenitor cells: 202.5;Other brain neurons: 34.0;Retinal amacrine cells: 241.1;Retinal ganglion cells: 46.4" "Cell type enhanced" "Detected in all" "oligodendrocyte precursor cell: 247.8" "Cancer enriched" "Detected in some" 4 "Glioblastoma Multiforme (TCGA): 19.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "Neuroblastoma: 4.9" "Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014479 Enhanced NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" 1 "HPA014479: " "unprognostic (2.93e-2)" "unprognostic (1.03e-1)" "unprognostic (2.44e-1)" "unprognostic (6.04e-2)" "unprognostic (1.88e-1)" "unprognostic (2.83e-2)" "unprognostic (1.45e-3)" "unprognostic (5.38e-2)" GSG1L2 ENSG00000214978 "GSG1 like 2" A8MUP6 17 9800608-9822079 "Essential proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 4 "Retinal bipolar cells: 4.3" "Cell type enhanced" "Detected in single" "upper-layer intratelencephalic: 1.0" "Cancer enriched" "Detected in single" 48 "Kidney Renal Clear Cell Carcinoma (TCGA): 13.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 11: Neuronal - Sensory perception" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "unprognostic (5.61e-2)" "unprognostic (1.65e-1)" GSK3A ENSG00000105723 "Glycogen synthase kinase 3 alpha" P49840 19 42226225-42242625 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism, Neurogenesis, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Signal transduction inhibitor, Transferase" "Alzheimer disease, Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 16.0;Brain inhibitory neurons: 15.2;Ependymal cells: 9.0;Late spermatids: 15.4;Oligodendrocyte progenitor cells: 8.7;Oligodendrocytes: 12.4;Other brain neurons: 15.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004422, HPA006495, HPA028423" Approved Approved Nucleoplasm,Cytosol NA NA 5300 "Cluster 21: Neutrophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 4: Non-specific - Transcription" "Cluster 98: Neurons - Neurotransmission & signaling" 88 Nucleoplasm Cytosol "CAB004422: , HPA006495: , HPA028423: " "unprognostic (1.38e-2)" "potential prognostic unfavorable (5.27e-4)" "unprognostic (1.07e-2)" "unprognostic (3.12e-3)" "unprognostic (1.94e-1)" "unprognostic (1.20e-2)" "unprognostic (2.27e-1)" "unprognostic (3.40e-1)" "unprognostic (1.27e-1)" "unprognostic (1.27e-1)" "potential prognostic favorable (6.19e-5)" "unprognostic (2.62e-2)" "unprognostic (1.13e-1)" "potential prognostic unfavorable (5.45e-5)" "unprognostic (1.85e-3)" "potential prognostic unfavorable (6.04e-4)" "unprognostic (1.81e-2)" "unprognostic (6.75e-2)" "unprognostic (1.20e-1)" "unprognostic (1.52e-1)" "unprognostic (1.77e-1)" "potential prognostic favorable (3.95e-4)" "unprognostic (1.03e-1)" "unprognostic (2.59e-1)" "unprognostic (2.19e-1)" "unprognostic (1.07e-1)" "unprognostic (2.79e-1)" "unprognostic (1.68e-1)" "unprognostic (5.26e-1)" "unprognostic (2.53e-3)" "unprognostic (4.60e-2)" GSK3B ENSG00000082701 "Glycogen synthase kinase 3 beta" P49841 3 119821321-120094994 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms, Carbohydrate metabolism, Differentiation, Glycogen metabolism, Neurogenesis, Wnt signaling pathway" "Developmental protein, Kinase, Serine/threonine-protein kinase, Signal transduction inhibitor, Transferase" "Alzheimer disease, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 760.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006495, CAB016263, HPA028017, CAB080481, CAB080483, CAB080485, CAB080488, CAB080489" Approved Enhanced Nucleoplasm No No "Cluster 45: Eosinophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 61: BICR 18 - Protein kinases" "Cluster 24: Neutrophils - Innate immunity signal integration" 251 Nucleoplasm "CAB016263: , CAB080481: , CAB080483: , CAB080485: , CAB080488: , CAB080489: , HPA006495: , HPA028017: " "unprognostic (3.14e-1)" "unprognostic (8.88e-3)" "unprognostic (1.63e-1)" "unprognostic (4.60e-3)" "unprognostic (1.97e-1)" "unprognostic (1.40e-1)" "unprognostic (1.28e-1)" "unprognostic (4.12e-3)" "unprognostic (8.81e-2)" "unprognostic (4.59e-3)" "potential prognostic favorable (1.09e-4)" "unprognostic (3.34e-1)" "unprognostic (1.31e-1)" "unprognostic (5.99e-3)" "unprognostic (2.60e-1)" "unprognostic (2.98e-2)" "unprognostic (1.05e-1)" "unprognostic (1.57e-1)" "unprognostic (4.50e-2)" "unprognostic (1.35e-3)" "unprognostic (1.57e-3)" "unprognostic (1.01e-2)" "unprognostic (1.02e-2)" "unprognostic (4.47e-2)" "unprognostic (8.79e-2)" "unprognostic (6.96e-2)" "unprognostic (1.80e-1)" "unprognostic (3.60e-1)" "unprognostic (3.08e-1)" "unprognostic (2.07e-1)" "unprognostic (2.51e-1)" GSKIP C14orf129 ENSG00000100744 "GSK3B interacting protein" Q9P0R6 14 96363452-96387288 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 440.7;Esophageal apical cells: 336.0;Late spermatids: 419.0;Oocytes: 165.8;Syncytiotrophoblasts: 151.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043054, HPA046782" Approved Approved "Nucleoli,Golgi apparatus,Vesicles" No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 42: Retina - Visual perception" "Cluster 14: Neurons - Synaptic function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 10 "Golgi apparatus, Vesicles" Nucleoli "HPA043054: , HPA046782: " "unprognostic (6.79e-2)" "unprognostic (7.37e-2)" "unprognostic (5.50e-2)" "unprognostic (2.60e-3)" "unprognostic (1.47e-1)" "unprognostic (1.30e-1)" "unprognostic (3.12e-2)" "unprognostic (6.40e-2)" "unprognostic (1.03e-1)" "potential prognostic favorable (1.91e-5)" "unprognostic (3.55e-1)" "unprognostic (3.47e-1)" "unprognostic (1.40e-2)" "unprognostic (2.43e-2)" "unprognostic (2.86e-2)" "unprognostic (3.54e-1)" "unprognostic (2.50e-1)" "unprognostic (4.78e-2)" "unprognostic (2.13e-2)" "unprognostic (1.08e-2)" "unprognostic (1.69e-1)" "unprognostic (1.62e-1)" "unprognostic (1.20e-1)" "unprognostic (1.28e-3)" "unprognostic (1.38e-1)" "unprognostic (9.83e-2)" "unprognostic (2.78e-1)" "unprognostic (1.20e-2)" "unprognostic (2.74e-1)" GSN DKFZp313L0718 ENSG00000148180 Gelsolin P06396 9 121207794-121332843 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cilium biogenesis/degradation" "Actin capping, Actin-binding" "Amyloidosis, Cancer-related genes, Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 2454.2" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1512.0;Fibroblasts: 3017.0;Goblet cells: 1203.4;Vascular endothelial cells: 979.6" "Group enriched" "Detected in all" 4 "astrocyte: 235.7;Bergmann glia: 219.5;central nervous system macrophage: 315.0;committed oligodendrocyte precursor: 323.0;endothelial cell: 219.9;fibroblast: 740.1;oligodendrocyte: 706.2;pericyte: 270.4;vascular associated smooth muscle cell: 343.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 1140.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Colon - Fibroblasts, Minor Salivary Gland - Fibroblasts, Skin - Fibroblasts_2, Spleen - Fibroblasts_2, Thyroid gland - Fibroblasts" "Region enriched" "Detected in all" 4 "white matter: 869.4" "Low region specificity" "Detected in all" "CAB010823, CAB016728, CAB036009, HPA054026" Supported Supported "Actin filaments" "Secreted to blood" Other NA NA 112000000000 48000000000 "Cluster 29: Non-specific - Unknown function" "Cluster 35: Non-specific - Mixed function" "Cluster 30: White matter - Myelination" "Cluster 69: Skin cancer - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 155 "Actin filaments" "CAB010823: , CAB016728: , CAB036009: , HPA054026: " "unprognostic (5.43e-2)" "unprognostic (2.78e-2)" "unprognostic (8.76e-2)" "unprognostic (1.44e-1)" "unprognostic (7.10e-2)" "unprognostic (7.24e-2)" "unprognostic (5.09e-2)" "unprognostic (2.25e-1)" "unprognostic (2.44e-2)" "unprognostic (4.14e-1)" "validated prognostic favorable (1.66e-7)" "validated prognostic favorable (1.85e-5)" "unprognostic (2.93e-1)" "unprognostic (6.03e-2)" "unprognostic (3.22e-2)" "unprognostic (7.15e-2)" "unprognostic (2.34e-1)" "unprognostic (7.36e-2)" "unprognostic (8.71e-2)" "unprognostic (8.79e-2)" "unprognostic (1.84e-1)" "unprognostic (7.29e-2)" "unprognostic (4.66e-3)" "unprognostic (3.73e-1)" "unprognostic (3.46e-2)" "unprognostic (8.01e-2)" "unprognostic (1.71e-1)" "unprognostic (1.33e-2)" "unprognostic (3.18e-2)" "unprognostic (1.38e-2)" "unprognostic (2.21e-2)" GSPT1 "eRF3a, ETF3A, GST1" ENSG00000103342 "G1 to S phase transition 1" P15170 16 11868128-11916082 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Nonsense-mediated mRNA decay, Protein biosynthesis" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052488, HPA074588" Approved Approved Vesicles,Cytosol NA NA 240000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 9: T-cells - Adaptive immunity: Regulation" 170 Cytosol Vesicles "HPA052488: , HPA074588: " "unprognostic (7.02e-3)" "unprognostic (4.00e-3)" "unprognostic (2.67e-1)" "unprognostic (2.18e-2)" "unprognostic (4.99e-2)" "unprognostic (1.17e-2)" "unprognostic (1.29e-1)" "unprognostic (1.77e-1)" "unprognostic (5.74e-3)" "unprognostic (5.93e-3)" "potential prognostic favorable (1.07e-5)" "unprognostic (3.66e-1)" "unprognostic (5.87e-2)" "potential prognostic unfavorable (6.38e-5)" "unprognostic (1.29e-3)" "unprognostic (3.54e-2)" "unprognostic (1.50e-2)" "unprognostic (1.28e-1)" "unprognostic (4.32e-1)" "unprognostic (1.12e-1)" "unprognostic (3.33e-2)" "potential prognostic unfavorable (5.28e-5)" "unprognostic (8.51e-3)" "unprognostic (1.71e-1)" "unprognostic (1.30e-3)" "unprognostic (1.35e-2)" "unprognostic (2.22e-1)" "unprognostic (2.39e-1)" "unprognostic (1.98e-1)" "unprognostic (2.56e-3)" "unprognostic (3.39e-3)" GSPT2 "eRF3b, FLJ10441" ENSG00000189369 "G1 to S phase transition 2" Q8IYD1 X 51743442-51746232 "Predicted intracellular proteins" "Cell cycle, Nonsense-mediated mRNA decay, Protein biosynthesis" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 87.3;Late primary spermatocytes: 64.8;Late spermatids: 328.7;Müller glia: 52.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "testis cancer: 35.8" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044769, HPA074588" Approved Enhanced Cytosol NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 36: Brain & Liver - Signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 36: Non-specific - mRNA processing" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 30 Cytosol "HPA044769: , HPA074588: " "unprognostic (3.99e-2)" "unprognostic (1.11e-2)" "unprognostic (5.69e-2)" "unprognostic (4.37e-2)" "unprognostic (2.64e-1)" "unprognostic (2.64e-3)" "unprognostic (2.32e-1)" "unprognostic (9.53e-2)" "unprognostic (1.40e-2)" "unprognostic (7.22e-2)" "potential prognostic favorable (4.18e-4)" "unprognostic (1.32e-2)" "unprognostic (5.74e-2)" "unprognostic (2.59e-2)" "unprognostic (2.98e-2)" "unprognostic (4.41e-1)" "unprognostic (1.96e-2)" "unprognostic (2.04e-1)" "unprognostic (3.31e-2)" "unprognostic (4.21e-1)" "unprognostic (3.11e-1)" "unprognostic (1.05e-1)" "potential prognostic unfavorable (4.76e-4)" "unprognostic (2.15e-1)" "unprognostic (6.27e-2)" "unprognostic (1.95e-1)" "unprognostic (2.67e-1)" "unprognostic (1.86e-2)" "unprognostic (5.36e-3)" "unprognostic (1.78e-1)" "unprognostic (1.05e-3)" GSR ENSG00000104687 "Glutathione-disulfide reductase" P00390 8 30678066-30727846 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Cancer-related genes, Disease variant, FDA approved drug targets, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophil progenitors: 199.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 32.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary gland basal cells, Spleen - Macrophages, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001538, CAB008632, HPA064806" Approved Supported "Endoplasmic reticulum,Cytosol" NA NA 32000000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 76: Non-specific - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 48: Neutrophils - Phagocytosis & degranulation" Cytosol "Endoplasmic reticulum" "CAB008632: , HPA001538: , HPA064806: " "potential prognostic favorable (7.98e-4)" "unprognostic (7.89e-2)" "unprognostic (3.73e-1)" "unprognostic (1.39e-3)" "potential prognostic favorable (2.04e-4)" "unprognostic (1.15e-1)" "unprognostic (2.06e-1)" "unprognostic (2.40e-2)" "unprognostic (1.75e-1)" "unprognostic (1.95e-3)" "potential prognostic favorable (1.31e-5)" "unprognostic (7.44e-2)" "unprognostic (7.17e-3)" "potential prognostic unfavorable (3.93e-6)" "unprognostic (8.37e-2)" "unprognostic (1.48e-2)" "unprognostic (2.51e-2)" "unprognostic (1.38e-1)" "unprognostic (2.60e-1)" "unprognostic (7.21e-2)" "unprognostic (4.86e-2)" "unprognostic (3.53e-2)" "unprognostic (2.93e-2)" "unprognostic (7.79e-2)" "unprognostic (1.71e-2)" "unprognostic (7.69e-2)" "unprognostic (4.00e-2)" "unprognostic (2.36e-2)" "unprognostic (2.42e-1)" "unprognostic (2.48e-2)" "unprognostic (5.35e-2)" GSS ENSG00000100983 "Glutathione synthetase" P48637 20 34928432-34956027 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glutathione biosynthesis" Ligase "Disease variant, FDA approved drug targets, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Breast lactating cells: 151.7;Late spermatids: 320.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054508, HPA059315" Enhanced Supported Nucleoplasm NA NA 20000000 "Cluster 33: Non-specific - ATP binding" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 1 Nucleoplasm "HPA054508: , HPA059315: " "unprognostic (5.50e-2)" "unprognostic (2.64e-1)" "unprognostic (3.63e-2)" "unprognostic (1.95e-1)" "unprognostic (1.06e-1)" "unprognostic (9.71e-2)" "unprognostic (1.31e-2)" "unprognostic (2.83e-1)" "unprognostic (1.18e-1)" "unprognostic (6.07e-2)" "unprognostic (1.71e-2)" "unprognostic (3.83e-3)" "potential prognostic favorable (1.04e-7)" "potential prognostic unfavorable (8.01e-5)" "unprognostic (1.17e-3)" "unprognostic (1.55e-3)" "unprognostic (4.86e-2)" "unprognostic (8.46e-2)" "unprognostic (2.04e-1)" "unprognostic (2.43e-1)" "unprognostic (2.23e-1)" "unprognostic (1.08e-2)" "unprognostic (2.85e-1)" "unprognostic (8.52e-2)" "unprognostic (1.63e-2)" "unprognostic (1.22e-1)" "unprognostic (1.95e-1)" "unprognostic (1.02e-2)" "unprognostic (1.72e-1)" "unprognostic (1.13e-2)" "unprognostic (1.28e-2)" GSTA1 ENSG00000243955 "Glutathione S-transferase alpha 1" P08263 6 52791371-52803860 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" "Isomerase, Oxidoreductase, Peroxidase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 635.7;intestine: 635.6;kidney: 880.2;liver: 2438.9" "Cell type enhanced" "Detected in many" "Cholangiocytes: 368.9;Conjunctival goblet cells: 1159.2;Enteric transient amplifying cells: 695.6;Enterocytes: 3964.0;Granulosa cells: 579.1;Hepatocytes: 1378.2;Parietal cells: 914.0;Respiratory ciliated cells: 864.5;Respiratory secretory cells: 466.3" "Cell type enriched" "Detected in single" 4 "cerebellar inhibitory: 1.8" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 316.4;Liver Hepatocellular Carcinoma (TCGA): 712.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "liver cancer: 69.2" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Testis - Leydig cells" "HPA004342, HPA048934, HPA053817" Supported Supported Cytosol NA NA 6000000 "Cluster 76: Non-specific - Metabolism" "Cluster 7: Liver cancer - Metabolism" "Cluster 1: Enterocytes - Absorption and Digestion" 4 Cytosol "HPA004342: , HPA048934: , HPA053817: " "unprognostic (2.13e-1)" "unprognostic (9.07e-3)" "unprognostic (3.42e-1)" "unprognostic (2.56e-2)" "unprognostic (2.47e-1)" "unprognostic (9.59e-2)" "unprognostic (4.28e-3)" "unprognostic (3.14e-3)" "potential prognostic favorable (5.91e-4)" "unprognostic (1.64e-2)" "unprognostic (5.41e-2)" "unprognostic (4.29e-3)" "unprognostic (1.91e-3)" "unprognostic (8.32e-2)" "unprognostic (1.47e-2)" "unprognostic (3.47e-2)" "unprognostic (2.39e-2)" "unprognostic (3.15e-1)" "unprognostic (7.47e-2)" "unprognostic (1.22e-1)" "unprognostic (5.37e-2)" "unprognostic (4.56e-1)" "unprognostic (1.60e-2)" "unprognostic (3.81e-2)" "unprognostic (6.79e-2)" "unprognostic (4.22e-2)" GSTA2 GST2 ENSG00000244067 "Glutathione S-transferase alpha 2" P09210 6 52750087-52763475 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "kidney: 649.1;liver: 1924.8" "Cell type enhanced" "Detected in some" "Cholangiocytes: 174.4;Enteric transient amplifying cells: 86.6;Enterocytes: 303.5;Hepatocytes: 163.7;Pancreatic acinar cells: 195.5;Respiratory ciliated cells: 711.2" "Not detected" "Not detected" "Group enriched" "Detected in many" 19 "Kidney Renal Clear Cell Carcinoma (TCGA): 169.5;Liver Hepatocellular Carcinoma (TCGA): 244.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 8 "liver cancer: 21.5" "Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Testis - Sertoli cells" "HPA004342, HPA048934, HPA053817" Supported Supported Cytosol NA NA "Cluster 16: Liver & Kidney - Metabolism" "Cluster 7: Liver cancer - Metabolism" "Cluster 107: Ciliated cells - Cilia assembly & function" 8 Cytosol "HPA004342: , HPA048934: , HPA053817: " "unprognostic (4.67e-2)" "unprognostic (1.59e-1)" "validated prognostic favorable (9.08e-4)" "validated prognostic favorable (1.97e-4)" "unprognostic (1.14e-1)" "unprognostic (1.82e-1)" "unprognostic (9.90e-2)" "unprognostic (9.11e-3)" "unprognostic (6.75e-2)" "unprognostic (8.10e-2)" "unprognostic (1.55e-1)" "unprognostic (1.58e-1)" "unprognostic (9.71e-2)" "unprognostic (2.20e-1)" "unprognostic (8.26e-3)" "unprognostic (1.82e-1)" GSTA3 ENSG00000174156 "Glutathione S-transferase alpha 3" Q16772 6 52896639-52909698 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adrenal gland: 61.8;fallopian tube: 61.4;placenta: 21.3;skin 1: 24.5" "Cell type enhanced" "Detected in some" "Adrenal cortex cells: 53.9;Cytotrophoblasts: 324.9;Endometrial ciliated cells: 63.9;Epididymal efferent duct ciliated cells: 170.8;Fallopian tube ciliated cells: 239.3;Respiratory ciliated cells: 76.4;Syncytiotrophoblasts: 844.4" "Group enriched" "Detected in some" 10 "choroid plexus epithelial cell: 5.8;ependymal cell: 3.3" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 3.2;Uterine Corpus Endometrial Carcinoma (TCGA): 3.2" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 1.1;testis cancer: 1.3" "Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary gland basal cells" "HPA004342, HPA048934, HPA053817" Approved Supported Cytosol NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 3: Choroid plexus - Cilium" "Cluster 27: Breast cancer - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 1 Cytosol "HPA004342: , HPA048934: , HPA053817: " "unprognostic (4.24e-2)" "unprognostic (2.00e-1)" "unprognostic (1.49e-1)" "unprognostic (7.72e-2)" "unprognostic (6.75e-2)" "unprognostic (2.01e-1)" GSTA4 ENSG00000170899 "Glutathione S-transferase alpha 4" O15217 6 52977948-52995304 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 291.0" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 1227.3;Cytotrophoblasts: 390.3;Esophageal suprabasal cells: 298.3;Syncytiotrophoblasts: 644.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "non-classical monocyte: 20.1" "Lineage enriched" "Detected in many" 6 "monocytes: 20.1" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary gland basal cells" "Low region specificity" "Detected in all" HPA048934 Approved NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 31: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 18: Adrenal cortex cells - Steroidogensis" 9 "HPA048934: " "unprognostic (2.01e-1)" "potential prognostic unfavorable (8.90e-4)" "unprognostic (2.85e-1)" "unprognostic (2.00e-2)" "unprognostic (1.55e-1)" "unprognostic (1.93e-1)" "unprognostic (1.37e-1)" "unprognostic (1.44e-3)" "unprognostic (4.83e-2)" "unprognostic (1.76e-1)" "validated prognostic favorable (1.83e-6)" "validated prognostic favorable (5.05e-5)" "unprognostic (4.89e-2)" "unprognostic (1.55e-1)" "unprognostic (6.21e-2)" "unprognostic (4.92e-1)" "unprognostic (1.64e-1)" "unprognostic (1.06e-2)" "unprognostic (2.55e-2)" "unprognostic (1.25e-1)" "unprognostic (1.50e-1)" "unprognostic (7.05e-3)" "unprognostic (4.97e-2)" "unprognostic (4.44e-2)" "unprognostic (3.19e-1)" "unprognostic (7.12e-2)" "unprognostic (5.20e-3)" "unprognostic (1.77e-1)" "potential prognostic favorable (7.49e-4)" "unprognostic (4.40e-1)" "unprognostic (8.45e-2)" GSTA5 ENSG00000182793 "Glutathione S-transferase alpha 5" Q7RTV2 6 52831655-52840843 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Conjunctival goblet cells: 2.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in many" "HPA004342, HPA048934, HPA053817" Uncertain Approved Cytosol NA NA "Cluster 15: Kidney cancer - Membrane components" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 6 Cytosol "HPA004342: , HPA048934: , HPA053817: " GSTCD FLJ13273 ENSG00000138780 "Glutathione S-transferase C-terminal domain containing" Q8NEC7 4 105708778-105847725 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 311.7;Epicardial cells: 200.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 5.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046160, HPA061782" Approved Supported Nucleoplasm NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 42: Retina - Visual perception" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 9 Nucleoplasm "HPA046160: , HPA061782: " "unprognostic (1.32e-1)" "unprognostic (4.95e-2)" "unprognostic (2.60e-3)" "unprognostic (6.47e-2)" "unprognostic (6.15e-2)" "unprognostic (7.98e-2)" "unprognostic (1.52e-1)" "unprognostic (1.52e-1)" "unprognostic (2.67e-1)" "unprognostic (4.95e-3)" "potential prognostic favorable (6.29e-4)" "unprognostic (3.79e-3)" "unprognostic (1.22e-1)" "unprognostic (5.74e-3)" "unprognostic (5.77e-3)" "unprognostic (2.60e-3)" "unprognostic (5.19e-3)" "unprognostic (2.15e-1)" "unprognostic (7.80e-2)" "unprognostic (1.95e-2)" "unprognostic (1.37e-2)" "unprognostic (1.32e-2)" "potential prognostic unfavorable (5.35e-4)" "unprognostic (9.29e-2)" "potential prognostic favorable (1.83e-4)" "unprognostic (5.99e-3)" "unprognostic (1.34e-1)" "unprognostic (3.01e-1)" "unprognostic (1.70e-1)" "unprognostic (3.19e-3)" "unprognostic (8.83e-2)" GSTK1 GST13 ENSG00000197448 "Glutathione S-transferase kappa 1" Q9Y2Q3 7 143244093-143270854 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 663.5;Enterocytes: 588.0;Late spermatids: 1578.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006311, HPA022904" Supported Supported Peroxisomes NA NA 140000 "Cluster 33: Non-specific - ATP binding" "Cluster 76: Non-specific - Metabolism" "Cluster 36: Choroid plexus - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 8 Peroxisomes "HPA006311: , HPA022904: " "unprognostic (4.51e-3)" "unprognostic (1.61e-3)" "unprognostic (4.59e-2)" "unprognostic (1.20e-1)" "unprognostic (2.65e-2)" "unprognostic (3.81e-1)" "unprognostic (2.64e-3)" "unprognostic (3.30e-3)" "unprognostic (3.49e-2)" "unprognostic (8.79e-2)" "potential prognostic favorable (3.26e-4)" "unprognostic (9.24e-2)" "potential prognostic favorable (1.21e-6)" "unprognostic (2.04e-1)" "unprognostic (9.83e-3)" "unprognostic (1.18e-2)" "unprognostic (2.00e-1)" "unprognostic (2.28e-1)" "unprognostic (8.09e-3)" "unprognostic (2.63e-3)" "unprognostic (9.64e-2)" "unprognostic (4.82e-3)" "unprognostic (9.40e-3)" "unprognostic (1.69e-1)" "unprognostic (1.94e-1)" "unprognostic (2.82e-1)" "unprognostic (2.67e-2)" "unprognostic (1.61e-2)" "unprognostic (8.32e-2)" "unprognostic (2.33e-2)" "unprognostic (1.80e-2)" GSTM1 "GST1, H-B, MU" ENSG00000134184 "Glutathione S-transferase mu 1" P09488 1 109687814-109709039 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 569.8" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 7.5;Hematopoietic stem cells: 3.9;Hepatic stellate cells: 6.5;Kupffer cells: 7.2;Medullary thymic epithelial cells: 4.8;Peritubular myoid cells: 4.1;Platelets: 4.2;Suprabasal keratinocytes: 5.6;Urothelial cells: 13.0" "Cell type enhanced" "Detected in some" "Bergmann glia: 2.4;choroid plexus epithelial cell: 1.0" "Cancer enhanced" "Detected in all" "Bladder Urothelial Carcinoma (TCGA): 484.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB022669, CAB047357, HPA048652, HPA055972, HPA055973" Approved Approved "Microtubules,Cytokinetic bridge,Primary cilium,Primary cilium tip,Primary cilium transition zone,Cytosol" Yes NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 50: Lymphoma - Unknown function" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 1 Cytosol "Microtubules, Cytokinetic bridge, Primary cilium, Primary cilium tip, Primary cilium transition zone" "CAB022669: , CAB047357: , HPA048652: , HPA055972: , HPA055973: " "unprognostic (1.13e-2)" "unprognostic (3.23e-2)" "unprognostic (2.37e-1)" "unprognostic (5.80e-2)" "unprognostic (1.39e-2)" "unprognostic (2.19e-1)" "unprognostic (8.50e-2)" "unprognostic (2.13e-1)" "unprognostic (1.58e-1)" "unprognostic (2.12e-1)" "unprognostic (1.30e-2)" "unprognostic (2.16e-1)" "unprognostic (2.13e-1)" "unprognostic (3.03e-2)" "unprognostic (1.47e-2)" "unprognostic (3.45e-1)" "unprognostic (1.14e-1)" "unprognostic (6.85e-2)" "unprognostic (1.30e-1)" "unprognostic (5.08e-2)" "unprognostic (1.14e-1)" "unprognostic (2.66e-1)" "unprognostic (1.38e-2)" "unprognostic (3.76e-1)" "unprognostic (3.42e-1)" "unprognostic (4.25e-2)" "unprognostic (4.27e-1)" "unprognostic (2.19e-1)" "unprognostic (9.72e-2)" "unprognostic (2.77e-1)" "unprognostic (1.30e-1)" GSTM2 GST4 ENSG00000213366 "Glutathione S-transferase mu 2" P28161 1 109668022-109709551 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 36.9;Fibro-adipogenic progenitors: 48.7;Hematopoietic stem cells: 75.2;Mast cells: 64.3;Medullary thymic epithelial cells: 40.8;Pituitary stem cells: 38.6" "Cell type enhanced" "Detected in many" "astrocyte: 16.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Bone cancer: 63.7" "Colon - Enteric glia cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "CAB040547, HPA055972, HPA055973" Approved Supported "Vesicles,Microtubules,Cytokinetic bridge,Primary cilium tip,Primary cilium transition zone,Cytosol" Yes NA 1600000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 24: Non-specific - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 89: Adipocytes - Lipid metabolism" 8 Cytosol "Vesicles, Microtubules, Cytokinetic bridge, Primary cilium tip, Primary cilium transition zone" "CAB040547: , HPA055972: , HPA055973: " "unprognostic (3.14e-1)" "unprognostic (1.24e-2)" "unprognostic (1.14e-2)" "unprognostic (2.26e-2)" "unprognostic (8.71e-2)" "unprognostic (6.46e-2)" "unprognostic (1.21e-1)" "unprognostic (2.00e-1)" "unprognostic (2.77e-1)" "unprognostic (4.84e-2)" "unprognostic (6.67e-2)" "potential prognostic favorable (4.45e-4)" "unprognostic (2.05e-3)" "unprognostic (7.75e-2)" "potential prognostic favorable (3.07e-4)" "potential prognostic favorable (3.22e-5)" "unprognostic (1.28e-1)" "unprognostic (1.05e-1)" "unprognostic (5.43e-3)" "unprognostic (2.01e-1)" "unprognostic (9.55e-2)" "unprognostic (4.83e-3)" "unprognostic (2.14e-2)" "unprognostic (3.59e-1)" "unprognostic (3.95e-1)" "unprognostic (4.56e-3)" "unprognostic (2.16e-1)" "unprognostic (2.59e-3)" "unprognostic (2.42e-1)" "unprognostic (5.96e-2)" "unprognostic (7.87e-2)" GSTM3 GST5 ENSG00000134202 "Glutathione S-transferase mu 3" P21266 1 109733932-109741038 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 93.2" "Group enriched" "Detected in many" 4 "Early spermatids: 1991.2;Late primary spermatocytes: 3268.9;Late spermatids: 6017.8" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 155.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 2.4" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017130, HPA035190, CAB040583, HPA055972" Enhanced Supported "Microtubules,Cytokinetic bridge,Primary cilium,Primary cilium tip,Primary cilium transition zone,Cytosol" Yes NA 650000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 36 Cytosol "Microtubules, Cytokinetic bridge, Primary cilium, Primary cilium tip, Primary cilium transition zone" "CAB017130: , CAB040583: , HPA035190: , HPA055972: " "unprognostic (1.18e-1)" "unprognostic (1.40e-1)" "unprognostic (5.09e-3)" "unprognostic (3.16e-2)" "unprognostic (1.55e-1)" "unprognostic (2.99e-1)" "unprognostic (1.04e-1)" "unprognostic (6.58e-2)" "unprognostic (4.49e-2)" "unprognostic (4.23e-2)" "potential prognostic favorable (8.40e-5)" "unprognostic (1.76e-2)" "unprognostic (1.63e-1)" "unprognostic (5.17e-3)" "unprognostic (4.49e-2)" "unprognostic (5.89e-2)" "unprognostic (1.08e-1)" "unprognostic (4.61e-2)" "unprognostic (7.14e-2)" "unprognostic (2.48e-1)" "unprognostic (1.74e-1)" "unprognostic (1.16e-1)" "unprognostic (4.82e-3)" "unprognostic (9.17e-2)" "unprognostic (8.77e-2)" "unprognostic (3.42e-3)" "potential prognostic unfavorable (7.00e-6)" "unprognostic (1.50e-2)" "unprognostic (7.79e-2)" "unprognostic (2.94e-2)" "unprognostic (1.49e-1)" GSTM4 ENSG00000168765 "Glutathione S-transferase mu 4" Q03013 1 109656099-109665496 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Lyase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 128.0" "Cell type enhanced" "Detected in many" "Enteric stem cells: 78.3;Enteric transient amplifying cells: 117.2;Enterocytes: 335.0;Paneth cells: 104.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 9 "eosinophil: 343.9" "Lineage enriched" "Detected in all" 9 "granulocytes: 343.9" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048652, HPA055972, HPA055973" Approved Approved "Microtubules,Cytokinetic bridge,Primary cilium,Primary cilium tip,Cytosol" Yes NA 1700000 "Cluster 22: Eosinophils - Transcription" "Cluster 76: Non-specific - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 1: Enterocytes - Absorption and Digestion" 11 Cytosol "Microtubules, Cytokinetic bridge, Primary cilium, Primary cilium tip" "HPA048652: , HPA055972: , HPA055973: " "unprognostic (8.53e-2)" "unprognostic (3.38e-3)" "unprognostic (9.98e-2)" "unprognostic (2.10e-2)" "unprognostic (6.40e-3)" "unprognostic (1.11e-2)" "unprognostic (2.04e-1)" "unprognostic (1.12e-1)" "unprognostic (2.37e-2)" "unprognostic (2.41e-1)" "potential prognostic favorable (2.35e-5)" "unprognostic (1.31e-3)" "unprognostic (6.85e-2)" "unprognostic (2.09e-1)" "unprognostic (1.30e-1)" "unprognostic (2.86e-2)" "unprognostic (4.64e-2)" "unprognostic (3.77e-2)" "unprognostic (1.17e-1)" "unprognostic (1.31e-1)" "unprognostic (3.44e-1)" "unprognostic (2.09e-1)" "unprognostic (1.03e-2)" "unprognostic (9.86e-2)" "unprognostic (5.54e-2)" "unprognostic (1.56e-1)" "unprognostic (6.59e-2)" "unprognostic (9.68e-3)" "unprognostic (1.69e-1)" "unprognostic (1.38e-1)" "unprognostic (9.33e-2)" GSTM5 ENSG00000134201 "Glutathione S-transferase mu 5" P46439 1 109711780-109775428 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "breast: 874.2" "Cell type enhanced" "Detected in many" "Fibroblasts: 48.9;Hematopoietic stem cells: 90.7;Hepatic stellate cells: 45.2;Leydig cells: 106.9;Mast cells: 342.8;Megakaryocytes: 55.6;Müller glia: 148.3;Ovarian stromal cells: 144.0;Peritubular myoid cells: 107.8" "Group enriched" "Detected in many" 4 "astrocyte: 21.0;Bergmann glia: 38.4;choroid plexus epithelial cell: 20.6;fibroblast: 22.8" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 52.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "plasmacytoid DC: 3.9" "Lineage enriched" "Detected in single" 4 "dendritic cells: 3.9" "Group enriched" "Detected in some" 10 "Bone cancer: 2.8;head and neck cancer: 1.4" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Minor Salivary Gland - Fibroblasts, Pancreas - Fibroblasts, Pituitary gland - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "HPA055972, HPA055973" Approved Supported "Microtubules,Cytokinetic bridge,Primary cilium,Primary cilium tip,Primary cilium transition zone,Cytosol" Yes NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 55: Breast - Lactation" "Cluster 34: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 58: Mast cells - Allergic inflammatory responses" 18 Cytosol "Microtubules, Cytokinetic bridge, Primary cilium, Primary cilium tip, Primary cilium transition zone" "HPA055972: , HPA055973: " "unprognostic (2.29e-1)" "unprognostic (1.32e-1)" "unprognostic (1.72e-3)" "unprognostic (1.22e-2)" "unprognostic (3.00e-2)" "unprognostic (1.74e-1)" "unprognostic (7.99e-3)" "unprognostic (4.38e-2)" "unprognostic (2.25e-1)" "unprognostic (3.31e-1)" "unprognostic (3.43e-2)" "unprognostic (8.79e-3)" "potential prognostic favorable (9.88e-4)" "unprognostic (2.22e-1)" "unprognostic (1.45e-1)" "unprognostic (6.20e-2)" "unprognostic (1.65e-1)" "unprognostic (3.89e-2)" "unprognostic (2.32e-1)" "unprognostic (3.13e-2)" "unprognostic (8.38e-2)" "unprognostic (1.16e-1)" "unprognostic (7.01e-2)" "unprognostic (1.59e-2)" "unprognostic (1.44e-1)" "unprognostic (1.16e-3)" "unprognostic (1.23e-1)" GSTO1 "GSTTLp28, P28" ENSG00000148834 "Glutathione S-transferase omega 1" P78417 10 104235356-104267459 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Oxidoreductase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 614.1" "Cell type enhanced" "Detected in all" "Hepatocytes: 743.4;Hofbauer cells: 491.2;Megakaryocytes: 1483.6;Platelets: 2523.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037603, HPA037604" Enhanced NA NA 36000000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 76: Non-specific - Metabolism" "Cluster 27: Non-specific - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 47: Platelets - Hemostasis" 7 "HPA037603: , HPA037604: " "unprognostic (1.00e-2)" "unprognostic (6.16e-2)" "unprognostic (1.50e-1)" "unprognostic (1.06e-2)" "unprognostic (1.60e-2)" "unprognostic (1.99e-1)" "unprognostic (1.83e-2)" "unprognostic (1.02e-1)" "potential prognostic unfavorable (7.72e-5)" "unprognostic (1.49e-1)" "unprognostic (1.75e-1)" "unprognostic (4.67e-3)" "unprognostic (1.82e-1)" "unprognostic (2.90e-2)" "potential prognostic favorable (2.42e-4)" "unprognostic (4.64e-3)" "unprognostic (3.95e-3)" "unprognostic (2.60e-2)" "unprognostic (6.20e-2)" "unprognostic (1.53e-2)" "unprognostic (2.17e-2)" "unprognostic (1.20e-2)" "unprognostic (9.73e-2)" "unprognostic (1.88e-1)" "unprognostic (1.16e-1)" "unprognostic (4.64e-3)" "unprognostic (1.86e-2)" "unprognostic (1.07e-2)" "unprognostic (1.56e-1)" "unprognostic (7.02e-2)" "unprognostic (1.79e-2)" GSTO2 ENSG00000065621 "Glutathione S-transferase omega 2" Q9H4Y5 10 104268873-104304950 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Oxidoreductase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 19.4" "Cell type enhanced" "Detected in many" "Early spermatids: 487.9;Late spermatids: 559.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA048141 Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 21: Testis - Mixed function" "Cluster 34: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 9 "Nucleoplasm, Nucleoli" "HPA048141: " "unprognostic (2.38e-2)" "unprognostic (6.08e-2)" "unprognostic (6.59e-2)" "unprognostic (6.76e-2)" "unprognostic (1.80e-2)" "unprognostic (1.99e-1)" "unprognostic (6.91e-2)" "unprognostic (1.80e-2)" "unprognostic (2.86e-1)" "unprognostic (3.93e-1)" "unprognostic (7.11e-3)" "unprognostic (6.54e-3)" "potential prognostic favorable (9.01e-5)" "unprognostic (3.73e-1)" "unprognostic (3.40e-1)" "unprognostic (4.55e-3)" "unprognostic (1.14e-1)" "unprognostic (5.82e-2)" "unprognostic (2.51e-1)" "unprognostic (1.17e-1)" "unprognostic (3.21e-3)" "unprognostic (2.60e-1)" "unprognostic (1.95e-2)" "unprognostic (5.77e-2)" "unprognostic (4.98e-2)" "unprognostic (3.29e-2)" "unprognostic (3.64e-1)" "unprognostic (4.57e-1)" "unprognostic (4.13e-2)" "unprognostic (1.89e-1)" "unprognostic (2.44e-2)" GSTP1 "FAEES3, GST3, GSTP" ENSG00000084207 "Glutathione S-transferase pi 1" P09211 11 67583742-67586656 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 2859.0" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 10889.7;Esophageal basal cells: 7640.2;Esophageal suprabasal cells: 12507.9;Respiratory ciliated cells: 4104.7;Respiratory deuterosomal cells: 4315.5;Respiratory secretory cells: 4655.5;Suprabasal keratinocytes: 4210.2" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 256.0;pericyte: 267.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary gland basal cells" "Low region specificity" "Detected in all" "HPA019779, HPA019869" Enhanced Supported Mitochondria,Cytosol No No 40000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 36: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 42 "Mitochondria, Cytosol" "HPA019779: , HPA019869: " "potential prognostic unfavorable (1.96e-4)" "unprognostic (1.27e-1)" "unprognostic (8.18e-3)" "unprognostic (2.90e-2)" "unprognostic (8.92e-2)" "unprognostic (2.28e-1)" "unprognostic (8.79e-2)" "unprognostic (3.77e-2)" "unprognostic (4.70e-3)" "unprognostic (1.07e-1)" "unprognostic (4.34e-2)" "unprognostic (2.67e-1)" "unprognostic (1.98e-1)" "unprognostic (1.98e-1)" "unprognostic (1.65e-1)" "unprognostic (7.37e-2)" "unprognostic (8.40e-2)" "unprognostic (2.01e-1)" "unprognostic (2.03e-1)" "unprognostic (1.40e-2)" "unprognostic (3.52e-2)" "potential prognostic unfavorable (8.31e-4)" "unprognostic (7.73e-2)" "unprognostic (1.22e-2)" "unprognostic (1.28e-1)" "unprognostic (1.94e-1)" "unprognostic (3.33e-2)" "unprognostic (1.23e-1)" "unprognostic (2.78e-1)" "unprognostic (8.55e-2)" "unprognostic (1.20e-1)" GSTT2 ENSG00000099984 "Glutathione S-transferase theta 2 (gene/pseudogene)" 22 23980058-23983915 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skin 1: 3.3" "Cell type enhanced" "Detected in some" "Astrocytes: 4.7;Conjunctival goblet cells: 2.9;Ependymal cells: 3.1;Epididymal basal cells: 2.8;Lacrimal acinar cells: 4.5;Melanocytes: 5.6;Oligodendrocyte progenitor cells: 3.6;Schwann cells: 2.8" "Low cell type specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" HPA000750 Uncertain Approved Nucleoplasm,Cytosol No NA "Cluster 37: Skin - Keratinization" "Cluster 53: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 61: Schwann cells & Melanocytes - Mixed function" Cytosol Nucleoplasm "HPA000750: " GSTT2B GSTT2P ENSG00000133433 "Glutathione S-transferase theta 2B" P0CG30 22 23957414-23961195 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adrenal gland: 79.0;breast: 289.9" "Cell type enhanced" "Detected in some" "Astrocytes: 3.5;Bergmann glia: 2.0;Brain inhibitory neurons: 2.4;Distal convoluted tubule cells: 4.4;Ependymal cells: 2.5;Loop of henle epithelial cells: 6.8;Medullary thymic epithelial cells: 2.4;Microglia: 1.9;Oligodendrocyte progenitor cells: 3.6;Other brain neurons: 3.0;Papillary tip epithelial cells: 5.1;Proximal tubule cells: 3.8;Renal collecting duct intercalated cells: 3.5;Renal collecting duct principal cells: 5.6;Renal connecting tubule cells: 5.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" HPA000750 Uncertain Supported Nucleoplasm,Cytosol No No "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 53: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 105: Non-specific - Mixed function" 1 Cytosol Nucleoplasm "HPA000750: " "unprognostic (1.76e-3)" "unprognostic (2.84e-2)" "unprognostic (9.98e-2)" "unprognostic (9.18e-2)" "unprognostic (1.04e-1)" "unprognostic (4.75e-2)" "unprognostic (3.82e-1)" "unprognostic (4.32e-2)" "unprognostic (2.62e-1)" "unprognostic (1.48e-1)" "unprognostic (2.18e-1)" "unprognostic (6.46e-2)" "unprognostic (8.26e-2)" "unprognostic (3.14e-2)" "unprognostic (1.36e-1)" "unprognostic (7.54e-2)" "unprognostic (7.78e-2)" "unprognostic (2.68e-1)" "unprognostic (3.56e-1)" "unprognostic (2.76e-3)" "potential prognostic unfavorable (1.71e-4)" "unprognostic (3.14e-1)" "unprognostic (3.68e-1)" "unprognostic (9.58e-2)" "unprognostic (2.40e-1)" "unprognostic (1.11e-1)" "unprognostic (3.01e-1)" "unprognostic (1.70e-2)" "unprognostic (2.26e-1)" GSTT4 "GSTTP1, HS322B1A" ENSG00000276950 "Glutathione S-transferase theta 4" A0A1W2PR19 22 23998401-24005453 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 37 "testis: 3.6" "Group enriched" "Detected in some" 107 "Early spermatids: 235.5;Late primary spermatocytes: 106.0;Late spermatids: 206.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" GSTZ1 "GSTZ1-1, MAAI, MAI" ENSG00000100577 "Glutathione S-transferase zeta 1" O43708 14 77320996-77331597 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Phenylalanine catabolism, Tyrosine catabolism" "Isomerase, Multifunctional enzyme, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "liver: 245.7" "Cell type enhanced" "Detected in many" "Hepatocytes: 482.7;Late primary spermatocytes: 149.0;Late spermatids: 673.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004701 Approved Approved Nucleoplasm,Cytosol NA NA 250000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 93: Hepatocytes - Bile production & excretion" 7 Cytosol Nucleoplasm "HPA004701: " "potential prognostic unfavorable (1.61e-4)" "unprognostic (3.70e-2)" "unprognostic (1.24e-1)" "unprognostic (6.00e-2)" "unprognostic (1.14e-1)" "unprognostic (1.55e-2)" "unprognostic (2.59e-1)" "unprognostic (6.57e-2)" "unprognostic (4.03e-2)" "unprognostic (8.86e-3)" "unprognostic (1.75e-3)" "unprognostic (9.78e-3)" "unprognostic (6.20e-3)" "unprognostic (1.41e-2)" "unprognostic (1.16e-1)" "unprognostic (2.47e-2)" "unprognostic (1.30e-1)" "unprognostic (4.11e-2)" "unprognostic (2.22e-1)" "unprognostic (4.40e-3)" "unprognostic (1.09e-1)" "unprognostic (5.64e-2)" "unprognostic (3.07e-1)" "unprognostic (7.91e-2)" "unprognostic (1.85e-1)" "unprognostic (7.08e-2)" "unprognostic (4.17e-1)" "unprognostic (6.94e-2)" "unprognostic (1.44e-1)" "unprognostic (3.74e-1)" "unprognostic (7.31e-2)" GSX1 "Gsh-1, GSH1" ENSG00000169840 "GS homeobox 1" Q9H4S2 13 27792483-27794768 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 24 "brain: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 35 "Glioblastoma Multiforme (TCGA): 6.2" "Region enriched" "Detected in single" 19 "hypothalamus: 15.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in single" HPA047096 Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 14: Myeloid leukemia - Innate immune response" 1 "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA047096: " "unprognostic (2.17e-1)" "unprognostic (1.97e-2)" GSX2 Gsh2 ENSG00000180613 "GS homeobox 2" Q9BZM3 4 54099523-54102498 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant, Dystonia, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 17 "Glioblastoma Multiforme (TCGA): 4.7" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 1.2;Kidney cancer: 1.1" "Skin - Keratinocyte (granular)" "Region enhanced" "Detected in single" "basal ganglia: 1.2" "Not detected" "Not detected" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "unprognostic (3.35e-2)" "unprognostic (4.44e-2)" GTDC1 "FLJ11753, Hmat-Xa" ENSG00000121964 "Glycosyltransferase like domain containing 1" Q4AE62 2 143938068-144332568 "Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 506.4;Neutrophils: 1273.3;Oligodendrocytes: 448.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036694 Approved Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 53: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" Cytosol "HPA036694: " "unprognostic (1.15e-2)" "unprognostic (8.05e-2)" "unprognostic (3.11e-1)" "unprognostic (2.20e-2)" "unprognostic (1.10e-1)" "unprognostic (1.89e-1)" "unprognostic (2.68e-2)" "unprognostic (9.15e-3)" "unprognostic (1.18e-1)" "unprognostic (2.42e-2)" "unprognostic (1.02e-1)" "unprognostic (3.31e-1)" "unprognostic (2.24e-1)" "potential prognostic unfavorable (4.43e-6)" "unprognostic (1.93e-1)" "unprognostic (2.73e-3)" "unprognostic (4.34e-2)" "unprognostic (2.72e-1)" "unprognostic (1.44e-2)" "unprognostic (1.73e-1)" "unprognostic (4.08e-3)" "unprognostic (9.68e-3)" "unprognostic (5.41e-3)" "unprognostic (1.02e-1)" "unprognostic (1.63e-1)" "unprognostic (2.54e-2)" "unprognostic (1.28e-2)" "unprognostic (4.02e-3)" "unprognostic (1.05e-1)" "unprognostic (6.41e-2)" "unprognostic (7.09e-2)" GTF2A1 TFIIA ENSG00000165417 "General transcription factor IIA subunit 1" P52655 14 81175452-81221377 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 7.4" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000869 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 44: Plasma cells - Antibody production & secretion" 23 Nucleoplasm Cytosol "HPA000869: " "unprognostic (8.87e-2)" "unprognostic (3.89e-1)" "unprognostic (1.29e-1)" "unprognostic (6.09e-2)" "unprognostic (2.23e-1)" "unprognostic (2.17e-2)" "unprognostic (4.16e-2)" "unprognostic (1.38e-1)" "unprognostic (4.29e-2)" "unprognostic (6.10e-2)" "potential prognostic favorable (1.25e-5)" "unprognostic (2.46e-3)" "unprognostic (6.23e-2)" "unprognostic (4.98e-3)" "unprognostic (1.49e-1)" "unprognostic (1.06e-2)" "unprognostic (1.33e-1)" "unprognostic (9.11e-2)" "unprognostic (3.16e-1)" "unprognostic (5.54e-2)" "unprognostic (2.00e-3)" "unprognostic (3.31e-2)" "unprognostic (8.97e-2)" "unprognostic (5.30e-1)" "unprognostic (3.54e-2)" "unprognostic (8.20e-2)" "unprognostic (9.94e-2)" "unprognostic (5.31e-2)" "unprognostic (2.42e-1)" "unprognostic (2.86e-1)" "unprognostic (6.92e-2)" GTF2A1L ALF ENSG00000242441 "General transcription factor IIA subunit 1 like" Q9UNN4 2 48617798-48733148 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "testis: 56.1" "Cell type enriched" "Detected in some" 9 "Bergmann glia: 238.4" "Cell type enriched" "Detected in many" 5 "Bergmann glia: 255.6" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA074358 Supported Nucleoplasm,Cytosol NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 43: Hindbrain - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 28: Astrocytes - Homeostasis & neuron support" 1 Nucleoplasm Cytosol "HPA074358: " "unprognostic (5.26e-2)" "unprognostic (2.72e-1)" GTF2A2 "HsT18745, TFIIA" ENSG00000140307 "General transcription factor IIA subunit 2" P52657 15 59638062-59657541 "Essential proteins, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 457.5;Early spermatids: 806.0;Esophageal apical cells: 465.9;Late primary spermatocytes: 2591.5;Late spermatids: 1039.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044897, HPA077202" Enhanced Nucleoplasm NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 39: Testis - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 16 Nucleoplasm "HPA044897: , HPA077202: " "unprognostic (8.84e-2)" "unprognostic (5.78e-2)" "unprognostic (1.39e-2)" "unprognostic (6.79e-2)" "unprognostic (3.37e-1)" "unprognostic (5.46e-2)" "unprognostic (2.65e-1)" "unprognostic (2.19e-1)" "potential prognostic unfavorable (1.18e-4)" "potential prognostic unfavorable (5.44e-4)" "potential prognostic favorable (3.49e-7)" "unprognostic (1.17e-1)" "unprognostic (2.97e-1)" "unprognostic (2.98e-1)" "unprognostic (2.50e-3)" "unprognostic (1.17e-3)" "unprognostic (1.99e-1)" "unprognostic (2.00e-1)" "unprognostic (8.60e-2)" "unprognostic (2.64e-1)" "unprognostic (5.09e-2)" "unprognostic (3.29e-1)" "unprognostic (6.61e-3)" "unprognostic (8.38e-2)" "unprognostic (8.99e-2)" "unprognostic (5.14e-2)" "unprognostic (1.44e-1)" "unprognostic (1.97e-2)" "unprognostic (1.54e-1)" "unprognostic (1.87e-1)" "unprognostic (2.28e-1)" GTF2B TFIIB ENSG00000137947 "General transcription factor IIB" Q00403 1 88852633-88891944 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Acyltransferase, DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061626 Supported Supported "Nucleoplasm,Nuclear bodies" No No "Cluster 35: Neutrophils - Protein binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 37: Non-specific - mRNA processing" "Cluster 20: Non-specific - Transcription regulation" 84 "Nucleoplasm, Nuclear bodies" "HPA061626: " "unprognostic (1.47e-1)" "unprognostic (8.60e-2)" "unprognostic (1.69e-2)" "unprognostic (4.58e-2)" "potential prognostic favorable (3.26e-4)" "unprognostic (3.15e-3)" "unprognostic (1.55e-1)" "unprognostic (1.38e-1)" "unprognostic (1.58e-2)" "unprognostic (3.77e-3)" "potential prognostic favorable (1.75e-5)" "unprognostic (1.24e-3)" "unprognostic (3.34e-1)" "potential prognostic unfavorable (7.60e-4)" "unprognostic (7.41e-2)" "unprognostic (2.29e-1)" "unprognostic (2.77e-2)" "unprognostic (2.50e-2)" "unprognostic (3.87e-1)" "unprognostic (1.68e-1)" "unprognostic (3.28e-1)" "unprognostic (5.64e-3)" "unprognostic (4.09e-3)" "unprognostic (2.78e-1)" "unprognostic (1.20e-2)" "unprognostic (1.02e-1)" "unprognostic (6.52e-2)" "unprognostic (1.57e-2)" "unprognostic (3.12e-2)" "unprognostic (3.80e-2)" "unprognostic (3.32e-1)" GTF2E1 "FE, TFIIE-A" ENSG00000153767 "General transcription factor IIE subunit 1" P29083 3 120742637-120783069 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Megakaryocytes: 30.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009884, HPA056359, HPA066881" Supported Enhanced Nucleoplasm NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 39: Testis - Nuclear processes" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 7: Non-specific - Transcription" 29 Nucleoplasm "CAB009884: , HPA056359: , HPA066881: " "unprognostic (3.81e-1)" "unprognostic (1.65e-1)" "unprognostic (6.84e-3)" "unprognostic (1.04e-1)" "unprognostic (8.73e-3)" "unprognostic (2.03e-2)" "unprognostic (3.92e-1)" "unprognostic (1.20e-3)" "unprognostic (7.46e-2)" "unprognostic (1.67e-2)" "potential prognostic favorable (6.25e-4)" "unprognostic (1.46e-2)" "unprognostic (9.72e-2)" "unprognostic (1.59e-3)" "potential prognostic unfavorable (3.27e-4)" "unprognostic (4.64e-2)" "unprognostic (2.49e-2)" "unprognostic (8.15e-2)" "unprognostic (9.54e-2)" "unprognostic (2.55e-1)" "unprognostic (1.94e-2)" "unprognostic (3.32e-2)" "unprognostic (5.07e-2)" "unprognostic (1.29e-1)" "unprognostic (7.52e-3)" "unprognostic (9.80e-2)" "unprognostic (2.63e-2)" "unprognostic (6.57e-2)" "unprognostic (3.29e-1)" "unprognostic (8.38e-2)" "unprognostic (1.06e-1)" GTF2E2 "FE, TF2E2, TFIIE-B" ENSG00000197265 "General transcription factor IIE subunit 2" P29084 8 30578318-30658236 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004816, CAB009603, HPA025065" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 8: Pancreas - Proteolysis" "Cluster 35: Non-specific - DNA binding" "Cluster 40: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 25 Nucleoplasm Cytosol "CAB009603: , HPA004816: , HPA025065: " "unprognostic (2.86e-2)" "unprognostic (2.01e-1)" "unprognostic (1.14e-1)" "unprognostic (3.49e-2)" "potential prognostic favorable (8.63e-4)" "unprognostic (1.35e-2)" "unprognostic (9.62e-2)" "unprognostic (8.74e-2)" "unprognostic (1.59e-1)" "unprognostic (3.37e-3)" "unprognostic (1.22e-2)" "unprognostic (1.07e-1)" "unprognostic (4.03e-2)" "potential prognostic unfavorable (1.98e-4)" "unprognostic (1.12e-1)" "unprognostic (2.22e-3)" "unprognostic (1.11e-1)" "unprognostic (7.23e-2)" "unprognostic (6.26e-2)" "unprognostic (1.02e-1)" "unprognostic (7.43e-2)" "unprognostic (1.62e-3)" "unprognostic (1.53e-2)" "unprognostic (8.95e-2)" "unprognostic (3.92e-2)" "unprognostic (8.83e-2)" "unprognostic (6.84e-2)" "unprognostic (2.51e-1)" "unprognostic (4.56e-1)" "unprognostic (4.76e-2)" "unprognostic (5.40e-2)" GTF2F1 "BTF4, RAP74, TF2F1, TFIIF" ENSG00000125651 "General transcription factor IIF subunit 1" P35269 19 6379572-6393981 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 272.2;Late spermatids: 672.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022793, HPA028707, HPA070752" Supported Enhanced Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 23: Non-specific - Transcription" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 60 Nucleoplasm "HPA022793: , HPA028707: , HPA070752: " "unprognostic (5.89e-2)" "unprognostic (7.66e-2)" "unprognostic (8.06e-2)" "unprognostic (4.33e-2)" "unprognostic (6.77e-2)" "unprognostic (2.88e-1)" "unprognostic (3.20e-1)" "unprognostic (1.81e-1)" "unprognostic (4.29e-2)" "unprognostic (4.36e-2)" "validated prognostic favorable (1.61e-6)" "validated prognostic favorable (9.33e-4)" "unprognostic (3.40e-2)" "unprognostic (1.78e-1)" "unprognostic (9.74e-3)" "unprognostic (5.36e-3)" "unprognostic (2.38e-2)" "unprognostic (3.95e-2)" "unprognostic (7.47e-2)" "unprognostic (2.25e-1)" "unprognostic (2.50e-1)" "unprognostic (1.76e-2)" "unprognostic (2.82e-1)" "unprognostic (4.84e-2)" "unprognostic (3.54e-2)" "unprognostic (9.73e-2)" "unprognostic (4.70e-2)" "unprognostic (6.01e-2)" "unprognostic (4.69e-2)" "unprognostic (1.61e-1)" "unprognostic (2.62e-3)" GTF2F2 "BTF4, RAP30, TFIIF" ENSG00000188342 "General transcription factor IIF subunit 2" P13984 13 45120510-45284893 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epididymal basal cells: 418.5;Ocular epithelial cells: 388.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006912 Supported Supported Nucleoplasm,Microtubules NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 19: Non-specific - Unknown function" "Cluster 100: Stratified epithelial cells - Barrier functions" 38 Nucleoplasm Microtubules "HPA006912: " "unprognostic (3.49e-1)" "unprognostic (1.81e-1)" "unprognostic (8.02e-2)" "potential prognostic unfavorable (5.17e-4)" "unprognostic (1.99e-1)" "unprognostic (2.47e-2)" "unprognostic (7.47e-2)" "unprognostic (6.32e-2)" "potential prognostic unfavorable (6.38e-5)" "potential prognostic unfavorable (4.24e-4)" "potential prognostic favorable (3.91e-4)" "unprognostic (1.26e-1)" "unprognostic (7.04e-2)" "unprognostic (2.22e-2)" "potential prognostic unfavorable (2.05e-4)" "unprognostic (3.07e-3)" "unprognostic (4.41e-3)" "unprognostic (5.04e-2)" "unprognostic (1.98e-1)" "unprognostic (1.21e-3)" "potential prognostic unfavorable (7.52e-4)" "unprognostic (3.36e-2)" "unprognostic (5.27e-2)" "unprognostic (2.83e-2)" "unprognostic (4.41e-1)" "unprognostic (2.48e-1)" "unprognostic (1.04e-1)" "unprognostic (2.05e-1)" "unprognostic (2.42e-1)" "unprognostic (2.89e-1)" "unprognostic (6.22e-2)" GTF2H1 "BTF2, P62, TFIIH" ENSG00000110768 "General transcription factor IIH subunit 1" P32780 11 18322295-18367045 "Cancer-related genes, Essential proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction, Transcription, Transcription regulation" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 41.9;Bergmann glia: 39.6;Brain excitatory neurons: 46.5;Brain inhibitory neurons: 50.7;Choroid plexus epithelial cells: 90.0;Distal convoluted tubule cells: 41.2;Microglia: 46.9;Oligodendrocyte progenitor cells: 41.2;Oligodendrocytes: 48.9;Other brain neurons: 41.1;Podocytes: 53.2;Proximal tubule cells: 45.1;Renal connecting tubule cells: 39.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004637, HPA046660" Enhanced Supported Nucleoplasm NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 64: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 102: Non-specific - Mixed function" 69 Nucleoplasm "CAB004637: , HPA046660: " "unprognostic (8.54e-2)" "unprognostic (3.40e-1)" "unprognostic (5.68e-2)" "unprognostic (6.48e-3)" "unprognostic (3.84e-1)" "unprognostic (2.49e-1)" "unprognostic (1.32e-1)" "unprognostic (2.26e-2)" "unprognostic (1.07e-1)" "unprognostic (4.46e-2)" "unprognostic (4.73e-3)" "unprognostic (1.05e-2)" "unprognostic (7.66e-2)" "potential prognostic unfavorable (1.61e-8)" "unprognostic (2.87e-3)" "unprognostic (2.79e-2)" "unprognostic (8.84e-2)" "unprognostic (3.03e-1)" "unprognostic (6.92e-2)" "unprognostic (1.11e-1)" "unprognostic (1.52e-1)" "unprognostic (1.94e-1)" "unprognostic (5.57e-3)" "unprognostic (6.37e-3)" "unprognostic (2.25e-3)" "unprognostic (4.20e-2)" "unprognostic (1.50e-2)" "unprognostic (1.45e-1)" "unprognostic (2.69e-1)" "unprognostic (3.79e-3)" "unprognostic (1.80e-1)" GTF2H2 "BTF2, BTF2P44, p44, T-BTF2P44, TFIIH" ENSG00000145736 "General transcription factor IIH subunit 2" Q13888 5 71035016-71067689 "Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 36.2;Loop of henle epithelial cells: 37.9;Myonuclei: 14.7;Papillary tip epithelial cells: 18.1;Podocytes: 23.2;Proximal tubule cells: 24.3;Renal collecting duct intercalated cells: 35.1;Renal collecting duct principal cells: 21.3;Renal connecting tubule cells: 18.3" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 33.9;prostate cancer: 35.0" HPA047001 Supported "Nuclear speckles" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 75: Ovary - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 60: Prostate cancer - Unknown function" "Cluster 105: Non-specific - Mixed function" 28 "Nuclear speckles" "HPA047001: " "unprognostic (1.04e-1)" "unprognostic (2.99e-2)" "unprognostic (1.85e-1)" "unprognostic (6.58e-3)" "unprognostic (2.60e-1)" "unprognostic (3.43e-2)" "unprognostic (7.21e-2)" "unprognostic (5.20e-3)" "unprognostic (5.93e-2)" "unprognostic (1.14e-1)" "unprognostic (4.13e-1)" "unprognostic (2.60e-1)" "unprognostic (2.36e-2)" "unprognostic (2.62e-1)" "unprognostic (2.62e-1)" "unprognostic (2.27e-3)" "unprognostic (2.20e-2)" "unprognostic (2.22e-1)" "unprognostic (4.23e-3)" "unprognostic (6.97e-2)" "unprognostic (4.99e-2)" "unprognostic (5.79e-2)" "unprognostic (7.70e-2)" "unprognostic (1.65e-1)" "unprognostic (1.52e-1)" "unprognostic (1.57e-2)" "unprognostic (1.77e-1)" GTF2H2C ENSG00000183474 "GTF2H2 family member C" Q6P1K8 5 69560191-69595221 "Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bergmann glia: 22.6;Distal convoluted tubule cells: 45.2;Loop of henle epithelial cells: 48.7;Oligodendrocytes: 22.5;Papillary tip epithelial cells: 22.1;Podocytes: 23.5;Proximal tubule cells: 28.6;Renal collecting duct intercalated cells: 59.7;Renal collecting duct principal cells: 33.4;Renal connecting tubule cells: 31.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 10.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" HPA047001 Approved "Nuclear speckles" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 64: Non-specific - Transcription" "Cluster 9: Non-specific - Receptor signaling" "Cluster 60: Prostate cancer - Unknown function" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 16 "Nuclear speckles" "HPA047001: " "unprognostic (1.57e-2)" "unprognostic (1.88e-1)" "unprognostic (3.22e-2)" "unprognostic (2.16e-3)" "unprognostic (3.11e-2)" "unprognostic (2.76e-2)" "unprognostic (5.02e-2)" "unprognostic (1.31e-2)" "unprognostic (4.68e-3)" "unprognostic (4.52e-2)" "unprognostic (9.04e-2)" "unprognostic (2.25e-1)" "unprognostic (5.91e-2)" "unprognostic (3.16e-3)" "unprognostic (1.87e-1)" "unprognostic (1.67e-2)" "unprognostic (1.29e-1)" "unprognostic (1.25e-2)" "unprognostic (4.20e-2)" "unprognostic (1.58e-1)" "unprognostic (2.77e-1)" "unprognostic (2.47e-2)" "unprognostic (2.94e-2)" "unprognostic (1.36e-1)" "unprognostic (2.12e-1)" "unprognostic (5.51e-2)" "unprognostic (7.01e-2)" "unprognostic (9.86e-2)" "unprognostic (3.35e-1)" "unprognostic (6.71e-3)" "unprognostic (1.19e-1)" GTF2H3 "BTF2, P34, TFIIH" ENSG00000111358 "General transcription factor IIH subunit 3" Q13889 12 123633739-123662604 "Essential proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004844, HPA053562" Uncertain Supported Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 30: White matter - Myelination" "Cluster 38: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 27 Nucleoplasm "HPA004844: , HPA053562: " "unprognostic (1.83e-1)" "unprognostic (5.67e-2)" "unprognostic (1.87e-2)" "unprognostic (1.19e-2)" "unprognostic (1.14e-1)" "unprognostic (5.01e-2)" "unprognostic (2.13e-1)" "unprognostic (5.66e-2)" "unprognostic (5.96e-2)" "unprognostic (3.43e-2)" "potential prognostic favorable (8.93e-4)" "unprognostic (3.06e-1)" "unprognostic (5.33e-1)" "potential prognostic unfavorable (1.45e-5)" "unprognostic (1.53e-1)" "unprognostic (4.45e-2)" "unprognostic (1.25e-3)" "unprognostic (4.07e-2)" "unprognostic (4.04e-1)" "unprognostic (2.07e-1)" "unprognostic (3.75e-2)" "unprognostic (2.03e-2)" "unprognostic (6.84e-3)" "unprognostic (9.13e-2)" "potential prognostic favorable (7.88e-4)" "unprognostic (9.16e-2)" "unprognostic (1.10e-2)" "unprognostic (1.66e-1)" "unprognostic (3.81e-1)" "unprognostic (1.02e-2)" "unprognostic (9.50e-3)" GTF2H4 "P52, TFB2, TFIIH" ENSG00000213780 "General transcription factor IIH subunit 4" Q92759 6 30908207-30914106 "Essential proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 9.0;Bergmann glia: 6.7;Brain excitatory neurons: 7.1;Brain inhibitory neurons: 8.1;Choroid plexus epithelial cells: 2.7;Ependymal cells: 3.8;Microglia: 4.8;Oligodendrocyte progenitor cells: 7.1;Oligodendrocytes: 6.1;Other brain neurons: 6.6;Tuft cells: 11.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074336 Supported "Nuclear speckles" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 64: Non-specific - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 28: Non-specific - Nuclear processes" "Cluster 35: Neurons - Synaptic function & neurogenesis" 43 "Nuclear speckles" "HPA074336: " "unprognostic (5.15e-2)" "unprognostic (5.77e-2)" "unprognostic (1.77e-1)" "unprognostic (1.05e-1)" "unprognostic (1.31e-2)" "unprognostic (3.96e-1)" "unprognostic (2.38e-3)" "potential prognostic favorable (6.50e-4)" "unprognostic (7.28e-3)" "unprognostic (2.98e-1)" "unprognostic (5.38e-2)" "unprognostic (2.11e-1)" "unprognostic (1.26e-1)" "unprognostic (8.24e-2)" "unprognostic (1.38e-1)" "unprognostic (2.71e-1)" "unprognostic (3.17e-1)" "unprognostic (1.55e-1)" "unprognostic (3.55e-2)" "unprognostic (2.95e-2)" "unprognostic (6.29e-2)" "unprognostic (2.47e-1)" "unprognostic (5.00e-3)" "unprognostic (4.89e-2)" "unprognostic (2.71e-2)" "unprognostic (2.35e-1)" "unprognostic (7.45e-3)" "unprognostic (4.86e-2)" "unprognostic (2.73e-1)" "unprognostic (5.61e-2)" "unprognostic (5.30e-3)" GTF2H5 "bA120J8.2, C6orf175, FLJ30544, TFB5, TFIIH, TTD, TTD-A, TTDA" ENSG00000272047 "General transcription factor IIH subunit 5" Q6ZYL4 6 158168350-158199344 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 355.7;Esophageal apical cells: 475.2;Esophageal suprabasal cells: 392.1;Late primary spermatocytes: 494.9;Parietal cells: 397.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 31: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 97: Non-specific - Cellular respiration" 32 "unprognostic (8.17e-2)" "potential prognostic unfavorable (9.36e-4)" "unprognostic (2.51e-1)" "unprognostic (4.66e-3)" "unprognostic (2.36e-1)" "unprognostic (2.25e-3)" "unprognostic (9.78e-2)" "unprognostic (2.80e-1)" "unprognostic (1.38e-3)" "unprognostic (4.17e-3)" "unprognostic (4.65e-2)" "unprognostic (3.41e-3)" "unprognostic (8.31e-3)" "unprognostic (1.51e-1)" "unprognostic (6.19e-2)" "unprognostic (1.17e-3)" "unprognostic (1.75e-1)" "unprognostic (1.22e-2)" "unprognostic (1.33e-1)" "unprognostic (2.06e-1)" "unprognostic (1.08e-1)" "unprognostic (1.91e-2)" "unprognostic (4.26e-1)" "unprognostic (6.34e-2)" "unprognostic (1.17e-1)" "unprognostic (1.84e-1)" "unprognostic (1.22e-1)" "unprognostic (6.13e-3)" "unprognostic (1.66e-1)" GTF2I "BAP-135, BTKAP1, DIWS, IB291, SPIN, TFII-I, WBSCR6" ENSG00000263001 "General transcription factor IIi" P78347 7 74650231-74760692 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004595, HPA026638" Supported Enhanced Nucleoplasm NA NA 57000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 39: Non-specific - Transcription" "Cluster 105: Non-specific - Mixed function" 56 Nucleoplasm "CAB004595: , HPA026638: " "unprognostic (1.19e-1)" "unprognostic (1.86e-1)" "unprognostic (3.63e-1)" "unprognostic (3.10e-2)" "unprognostic (5.51e-2)" "unprognostic (1.33e-1)" "unprognostic (3.30e-1)" "unprognostic (8.27e-2)" "unprognostic (3.46e-2)" "validated prognostic favorable (2.81e-7)" "validated prognostic favorable (3.48e-4)" "unprognostic (1.30e-1)" "unprognostic (8.03e-2)" "unprognostic (2.63e-1)" "unprognostic (6.64e-2)" "unprognostic (1.76e-1)" "unprognostic (1.52e-2)" "unprognostic (1.97e-1)" "unprognostic (3.46e-1)" "unprognostic (9.82e-3)" "unprognostic (1.95e-1)" "unprognostic (4.35e-2)" "unprognostic (1.34e-1)" "unprognostic (3.42e-2)" "unprognostic (1.98e-1)" "unprognostic (2.00e-1)" "unprognostic (6.04e-2)" "unprognostic (2.29e-1)" GTF2IRD1 "BEN, Cream1, GTF3, MusTRD1, RBAP2, WBSCR11, WBSCR12" ENSG00000006704 "GTF2I repeat domain containing 1" Q9UHL9 7 74453790-74602605 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 65.9" "Cell type enhanced" "Detected in many" "Myonuclei: 690.1;Renal connecting tubule cells: 420.0;Rod photoreceptor cells: 419.4;Somatotrophs: 571.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044254 Approved Supported Nucleoplasm,Cytosol Yes No "Cluster 25: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 24 Nucleoplasm Cytosol "HPA044254: " "potential prognostic favorable (7.96e-4)" "unprognostic (4.26e-2)" "unprognostic (1.56e-1)" "unprognostic (1.01e-1)" "unprognostic (3.13e-1)" "unprognostic (2.65e-2)" "unprognostic (9.13e-2)" "unprognostic (7.82e-2)" "unprognostic (1.09e-1)" "unprognostic (1.91e-1)" "unprognostic (1.63e-3)" "unprognostic (1.39e-1)" "unprognostic (2.17e-1)" "unprognostic (1.01e-3)" "unprognostic (5.58e-2)" "unprognostic (1.18e-2)" "unprognostic (2.71e-1)" "unprognostic (2.21e-1)" "unprognostic (1.15e-1)" "unprognostic (7.15e-2)" "unprognostic (5.45e-2)" "unprognostic (3.18e-3)" "unprognostic (3.26e-3)" "unprognostic (6.69e-2)" "unprognostic (3.50e-3)" "unprognostic (2.17e-2)" "potential prognostic unfavorable (6.17e-4)" "unprognostic (2.31e-1)" "unprognostic (6.61e-2)" "unprognostic (1.72e-1)" "unprognostic (4.64e-2)" GTF2IRD2 "FLJ37938, GTF2IRD2A" ENSG00000196275 "GTF2I repeat domain containing 2" Q86UP8 7 74796151-74851605 "Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 18.2;Bergmann glia: 18.8;Choroid plexus epithelial cells: 39.5;Distal convoluted tubule cells: 52.0;Ependymal cells: 33.2;Loop of henle epithelial cells: 40.7;Oligodendrocyte progenitor cells: 16.9;Oligodendrocytes: 22.5;Papillary tip epithelial cells: 34.3;Podocytes: 38.5;Proximal tubule cells: 31.9;Renal collecting duct intercalated cells: 55.0;Renal collecting duct principal cells: 39.1;Renal connecting tubule cells: 43.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA056679, HPA056680" Supported Nucleoplasm NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 24: Non-specific - Transcription" "Cluster 46: Brainstem - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 105: Non-specific - Mixed function" 1 Nucleoplasm "HPA056679: , HPA056680: " "unprognostic (2.46e-2)" "unprognostic (6.96e-3)" "unprognostic (2.34e-1)" "unprognostic (3.99e-3)" "unprognostic (2.10e-1)" "unprognostic (2.14e-1)" "unprognostic (9.30e-3)" "unprognostic (4.56e-2)" "unprognostic (6.01e-2)" "unprognostic (9.42e-2)" "unprognostic (1.32e-1)" "potential prognostic favorable (7.03e-5)" "unprognostic (3.64e-2)" "unprognostic (1.73e-2)" "unprognostic (2.88e-3)" "unprognostic (1.89e-1)" "unprognostic (1.49e-1)" "unprognostic (2.27e-2)" "unprognostic (1.46e-1)" "unprognostic (1.31e-2)" "unprognostic (1.48e-1)" "unprognostic (1.11e-1)" "unprognostic (9.56e-2)" "unprognostic (3.76e-2)" "unprognostic (4.06e-3)" "unprognostic (9.94e-2)" "unprognostic (3.59e-2)" "unprognostic (5.82e-2)" "unprognostic (1.98e-1)" "unprognostic (4.14e-1)" "unprognostic (1.76e-1)" GTF2IRD2B ENSG00000174428 "GTF2I repeat domain containing 2B" Q6EKJ0 7 75092573-75149817 "Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 150.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 15.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA056679, HPA056680" Supported Nucleoplasm NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 39: Non-specific - Transcription" "Cluster 94: Gonadal somatic cells - Mixed function" 1 Nucleoplasm "HPA056679: , HPA056680: " "unprognostic (2.36e-2)" "unprognostic (2.55e-1)" "unprognostic (2.52e-1)" "unprognostic (3.34e-3)" "unprognostic (3.45e-1)" "unprognostic (3.99e-2)" "unprognostic (2.03e-1)" "unprognostic (3.13e-1)" "unprognostic (1.62e-1)" "unprognostic (7.55e-3)" "potential prognostic favorable (4.56e-4)" "unprognostic (1.59e-3)" "unprognostic (1.08e-1)" "unprognostic (1.54e-1)" "unprognostic (4.06e-3)" "unprognostic (2.93e-1)" "unprognostic (1.14e-1)" "unprognostic (3.11e-1)" "unprognostic (1.35e-1)" "unprognostic (4.58e-2)" "unprognostic (8.23e-2)" "unprognostic (1.24e-1)" "unprognostic (1.34e-1)" "unprognostic (2.58e-1)" "unprognostic (2.21e-1)" "unprognostic (1.60e-1)" "unprognostic (2.02e-1)" "unprognostic (3.32e-2)" "unprognostic (6.67e-2)" "unprognostic (1.63e-2)" "unprognostic (1.45e-1)" GTF3A "AP2, TFIIIA" ENSG00000122034 "General transcription factor IIIA" Q92664 13 27424619-27435823 "Essential proteins, Predicted intracellular proteins, Transcription factors" "Ribosome biogenesis, Transcription, Transcription regulation" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Megakaryocytes: 377.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007990 Supported Supported Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 27: Non-specific - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 2 Nucleoplasm "HPA007990: " "unprognostic (2.38e-2)" "unprognostic (3.77e-2)" "unprognostic (4.56e-2)" "unprognostic (1.44e-2)" "unprognostic (1.50e-1)" "unprognostic (6.29e-3)" "unprognostic (2.83e-1)" "unprognostic (5.04e-1)" "unprognostic (1.40e-2)" "unprognostic (9.85e-3)" "unprognostic (7.65e-2)" "potential prognostic unfavorable (4.36e-4)" "unprognostic (2.82e-1)" "validated prognostic unfavorable (2.72e-4)" "validated prognostic unfavorable (4.69e-5)" "unprognostic (1.63e-2)" "unprognostic (2.66e-3)" "unprognostic (7.26e-2)" "unprognostic (5.46e-1)" "unprognostic (1.82e-1)" "unprognostic (5.42e-2)" "unprognostic (1.62e-1)" "unprognostic (2.74e-1)" "unprognostic (2.06e-2)" "unprognostic (6.25e-2)" "unprognostic (1.51e-2)" "unprognostic (7.18e-2)" "unprognostic (1.11e-1)" "unprognostic (3.56e-1)" "unprognostic (4.83e-1)" "unprognostic (1.91e-1)" GTF3C1 TFIIIC220 ENSG00000077235 "General transcription factor IIIC subunit 1" Q12789 16 27459555-27549913 "Essential proteins, Predicted intracellular proteins, Predicted membrane proteins" Transcription DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 161.5;Esophageal apical cells: 238.5;Prostatic glandular cells: 179.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "gdT-cell: 32.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Skin - Keratinocyte (other), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051617, HPA075900" Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 34 "Nucleoplasm, Nucleoli" "HPA051617: , HPA075900: " "unprognostic (6.16e-2)" "unprognostic (2.72e-2)" "unprognostic (1.27e-1)" "unprognostic (1.55e-1)" "unprognostic (2.97e-1)" "unprognostic (8.41e-2)" "unprognostic (1.36e-1)" "potential prognostic favorable (2.75e-6)" "unprognostic (8.92e-2)" "unprognostic (3.82e-1)" "unprognostic (6.47e-2)" "unprognostic (1.63e-1)" "unprognostic (3.63e-1)" "potential prognostic unfavorable (6.58e-7)" "unprognostic (7.20e-2)" "unprognostic (6.09e-3)" "unprognostic (8.10e-3)" "unprognostic (1.00e-1)" "unprognostic (6.44e-2)" "unprognostic (6.58e-2)" "unprognostic (4.09e-2)" "unprognostic (9.83e-3)" "unprognostic (5.55e-3)" "unprognostic (1.68e-1)" "unprognostic (2.24e-1)" "unprognostic (5.85e-2)" "unprognostic (1.56e-1)" "unprognostic (2.18e-1)" "unprognostic (3.31e-1)" "unprognostic (2.69e-2)" "unprognostic (6.64e-3)" GTF3C2 "KIAA0011, TFIIIC110" ENSG00000115207 "General transcription factor IIIC subunit 2" Q8WUA4 2 27325849-27356999 "Essential proteins, Predicted intracellular proteins" Transcription "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 206.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008274, HPA035836" Uncertain Supported Nucleoplasm NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 48: Non-specific - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 22 Nucleoplasm "HPA008274: , HPA035836: " "unprognostic (2.16e-1)" "unprognostic (5.27e-2)" "potential prognostic favorable (5.85e-4)" "unprognostic (4.55e-2)" "unprognostic (2.10e-1)" "unprognostic (5.21e-2)" "unprognostic (8.98e-2)" "potential prognostic favorable (2.46e-4)" "unprognostic (1.20e-1)" "unprognostic (8.02e-3)" "unprognostic (1.08e-2)" "unprognostic (1.32e-1)" "unprognostic (8.62e-3)" "potential prognostic unfavorable (1.31e-6)" "unprognostic (6.80e-3)" "unprognostic (7.54e-3)" "unprognostic (6.36e-3)" "potential prognostic favorable (6.03e-4)" "unprognostic (1.33e-1)" "unprognostic (2.33e-1)" "unprognostic (2.03e-1)" "unprognostic (3.36e-2)" "unprognostic (2.40e-3)" "unprognostic (6.74e-2)" "unprognostic (2.03e-1)" "unprognostic (1.14e-1)" "unprognostic (1.85e-1)" "unprognostic (1.37e-1)" "unprognostic (1.34e-1)" "unprognostic (7.48e-2)" "unprognostic (7.15e-2)" GTF3C3 "TFIIIC102, TFiiiC2-102" ENSG00000119041 "General transcription factor IIIC subunit 3" Q9Y5Q9 2 196763035-196799725 "Essential proteins, Predicted intracellular proteins, Predicted membrane proteins" Transcription DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069179 Supported "Nucleoplasm,Nuclear membrane,Nucleoli fibrillar center" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 40: Non-specific - Mixed function" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 7: Non-specific - Transcription" 77 "Nucleoplasm, Nuclear membrane" "Nucleoli fibrillar center" "HPA069179: " "unprognostic (1.85e-2)" "unprognostic (7.07e-2)" "unprognostic (1.20e-1)" "unprognostic (9.02e-2)" "unprognostic (9.63e-3)" "unprognostic (3.39e-1)" "unprognostic (8.68e-2)" "unprognostic (2.95e-2)" "unprognostic (2.14e-1)" "unprognostic (3.85e-3)" "potential prognostic unfavorable (1.17e-4)" "unprognostic (1.83e-2)" "unprognostic (3.10e-1)" "potential prognostic unfavorable (1.80e-5)" "unprognostic (6.56e-3)" "unprognostic (3.61e-3)" "unprognostic (1.28e-2)" "unprognostic (6.04e-3)" "unprognostic (1.13e-1)" "unprognostic (6.21e-2)" "unprognostic (3.03e-1)" "unprognostic (3.90e-2)" "unprognostic (2.27e-3)" "unprognostic (1.43e-1)" "unprognostic (4.28e-2)" "unprognostic (2.40e-3)" "unprognostic (2.57e-2)" "unprognostic (3.57e-2)" "unprognostic (1.64e-1)" "unprognostic (1.19e-1)" "unprognostic (1.84e-1)" GTF3C4 "KAT12, TFIIIC90" ENSG00000125484 "General transcription factor IIIC subunit 4" Q9UKN8 9 132670035-132694953 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" Transcription "Acyltransferase, DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069369 Supported Nucleoplasm,Mitochondria No No "Cluster 61: Non-specific - Transcription" "Cluster 35: Non-specific - DNA binding" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 17: Non-specific - RNA processing" 31 Nucleoplasm Mitochondria "HPA069369: " "unprognostic (1.06e-1)" "unprognostic (1.45e-2)" "unprognostic (2.60e-1)" "unprognostic (1.83e-1)" "unprognostic (1.26e-1)" "unprognostic (1.99e-2)" "unprognostic (1.32e-1)" "unprognostic (9.49e-3)" "unprognostic (2.39e-1)" "unprognostic (3.70e-1)" "potential prognostic favorable (3.75e-7)" "unprognostic (5.71e-3)" "unprognostic (1.62e-1)" "unprognostic (1.27e-2)" "unprognostic (2.84e-2)" "unprognostic (4.25e-2)" "unprognostic (3.40e-3)" "unprognostic (1.36e-1)" "unprognostic (2.40e-2)" "unprognostic (1.26e-1)" "unprognostic (5.63e-2)" "unprognostic (1.80e-1)" "unprognostic (4.56e-1)" "unprognostic (1.16e-2)" "unprognostic (1.72e-3)" "unprognostic (3.91e-1)" "unprognostic (3.91e-1)" "unprognostic (5.11e-2)" "unprognostic (3.23e-1)" "unprognostic (1.47e-1)" "unprognostic (2.25e-1)" GTF3C5 "TFiiiC2-63, TFIIIC63, TFIIICepsilon" ENSG00000148308 "General transcription factor IIIC subunit 5" Q9Y5Q8 9 133030675-133058503 "Essential proteins, Predicted intracellular proteins" Transcription DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 104.5;Epididymal principal cells: 85.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "HPA067063, HPA069805" Supported Enhanced Nucleoplasm NA NA "Cluster 41: Basophils - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 97: Non-specific - Cellular respiration" 29 Nucleoplasm "HPA067063: , HPA069805: " "unprognostic (5.98e-2)" "unprognostic (1.94e-2)" "unprognostic (1.25e-1)" "unprognostic (1.61e-1)" "unprognostic (1.73e-1)" "unprognostic (1.27e-2)" "unprognostic (1.19e-1)" "potential prognostic favorable (1.45e-4)" "unprognostic (1.75e-1)" "unprognostic (1.80e-1)" "potential prognostic favorable (7.64e-5)" "unprognostic (8.37e-3)" "unprognostic (1.58e-2)" "potential prognostic unfavorable (9.12e-4)" "unprognostic (2.28e-3)" "unprognostic (7.58e-3)" "unprognostic (7.67e-2)" "unprognostic (3.19e-1)" "unprognostic (1.88e-2)" "unprognostic (1.75e-1)" "unprognostic (1.18e-2)" "unprognostic (1.13e-1)" "unprognostic (2.28e-2)" "unprognostic (4.05e-2)" "unprognostic (2.32e-1)" "unprognostic (1.35e-1)" "unprognostic (2.18e-1)" "unprognostic (4.79e-3)" "unprognostic (2.61e-2)" "unprognostic (2.58e-1)" "unprognostic (2.24e-2)" GTF3C6 "bA397G5.3, C6orf51, TFIIIC35" ENSG00000155115 "General transcription factor IIIC subunit 6" Q969F1 6 110958706-110967890 "Predicted intracellular proteins" Transcription DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 352.0;Esophageal suprabasal cells: 379.6;Hofbauer cells: 412.2;Late spermatids: 369.9;Platelets: 488.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Prostate - Prostate glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056179, HPA061345" Approved Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 28: Non-specific - Nuclear processes" "Cluster 97: Non-specific - Cellular respiration" 9 Nucleoplasm "Nuclear bodies" "HPA056179: , HPA061345: " "unprognostic (1.56e-2)" "unprognostic (3.61e-3)" "unprognostic (6.10e-2)" "unprognostic (7.02e-2)" "unprognostic (4.01e-2)" "unprognostic (8.71e-2)" "unprognostic (7.21e-2)" "unprognostic (1.23e-1)" "unprognostic (9.89e-2)" "unprognostic (1.35e-2)" "unprognostic (2.53e-2)" "unprognostic (1.42e-1)" "unprognostic (4.74e-1)" "validated prognostic unfavorable (1.73e-7)" "validated prognostic unfavorable (2.79e-4)" "validated prognostic unfavorable (2.08e-5)" "validated prognostic unfavorable (9.16e-4)" "unprognostic (9.40e-3)" "unprognostic (1.86e-1)" "unprognostic (2.09e-1)" "unprognostic (2.42e-1)" "unprognostic (8.41e-2)" "unprognostic (3.85e-1)" "unprognostic (6.77e-2)" "unprognostic (1.60e-1)" "unprognostic (3.16e-2)" "unprognostic (6.77e-2)" "unprognostic (1.25e-1)" "unprognostic (4.63e-1)" "unprognostic (2.90e-2)" "unprognostic (3.41e-1)" GTPBP1 "GP-1, HSPC018" ENSG00000100226 "GTP binding protein 1" O00178 22 38705742-38738299 "Predicted intracellular proteins" "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 100.4" "Cell type enriched" "Detected in all" 4 "Neutrophils: 719.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003166, HPA064702" Approved Approved "Nuclear bodies,Golgi apparatus,Cytosol" NA NA 13000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 15: Bone marrow - Innate immune response" "Cluster 55: Non-specific - Transcription" "Cluster 66: Non-specific - Mitochondria" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 15 "Golgi apparatus, Cytosol" "Nuclear bodies" "HPA003166: , HPA064702: " "unprognostic (8.96e-2)" "unprognostic (3.43e-3)" "unprognostic (1.76e-1)" "unprognostic (1.32e-1)" "unprognostic (2.99e-1)" "unprognostic (3.47e-2)" "unprognostic (7.39e-3)" "unprognostic (5.55e-2)" "unprognostic (9.72e-2)" "unprognostic (5.86e-2)" "unprognostic (3.71e-3)" "unprognostic (1.72e-2)" "unprognostic (2.08e-2)" "unprognostic (8.01e-3)" "unprognostic (2.40e-1)" "unprognostic (8.79e-2)" "unprognostic (1.41e-1)" "unprognostic (1.24e-1)" "unprognostic (1.27e-2)" "unprognostic (7.00e-2)" "unprognostic (6.16e-1)" "unprognostic (2.32e-2)" "unprognostic (8.12e-3)" "unprognostic (2.09e-1)" "unprognostic (1.36e-3)" "potential prognostic favorable (2.54e-4)" "unprognostic (1.56e-1)" "unprognostic (2.10e-1)" "unprognostic (1.46e-1)" "unprognostic (2.16e-2)" "unprognostic (2.69e-1)" GTPBP10 "DKFZP686A10121, FLJ38242, OBGH2" ENSG00000105793 "GTP binding protein 10" A4D1E9 7 90335223-90391453 "Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 135.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021076 Approved NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 76: Non-specific - Metabolism" "Cluster 16: Non-specific - Transcription" "Cluster 39: Non-specific - Transcription" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 28 "HPA021076: " "unprognostic (5.53e-3)" "unprognostic (3.82e-1)" "unprognostic (5.11e-2)" "unprognostic (2.63e-3)" "unprognostic (2.52e-1)" "unprognostic (1.68e-1)" "unprognostic (1.29e-1)" "unprognostic (3.05e-1)" "unprognostic (2.15e-2)" "unprognostic (4.83e-2)" "potential prognostic favorable (4.50e-7)" "unprognostic (5.60e-2)" "unprognostic (3.02e-2)" "unprognostic (3.59e-1)" "unprognostic (1.36e-1)" "unprognostic (5.27e-3)" "unprognostic (1.62e-3)" "unprognostic (2.13e-1)" "unprognostic (2.77e-1)" "unprognostic (4.73e-1)" "unprognostic (5.49e-3)" "potential prognostic unfavorable (5.78e-5)" "unprognostic (1.55e-2)" "unprognostic (5.99e-2)" "unprognostic (5.04e-2)" "unprognostic (3.48e-2)" "unprognostic (7.60e-2)" "unprognostic (2.16e-2)" "unprognostic (2.58e-1)" "unprognostic (9.44e-2)" "unprognostic (4.72e-2)" GTPBP2 ENSG00000172432 "GTP binding protein 2" Q9BX10 6 43605316-43629264 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 83.5;Late spermatids: 94.2;Platelets: 276.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 5.4" "Lineage enriched" "Detected in many" 4 "granulocytes: 5.4" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031418, HPA031419" Approved Approved Vesicles NA Yes 4600 "Cluster 7: Non-specific - Innate immune response" "Cluster 64: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 13: Non-specific - Mixed function" "Cluster 47: Platelets - Hemostasis" 20 Vesicles "HPA031418: , HPA031419: " "unprognostic (1.31e-1)" "unprognostic (6.90e-2)" "unprognostic (6.20e-2)" "unprognostic (1.77e-1)" "unprognostic (2.80e-1)" "unprognostic (3.62e-1)" "unprognostic (9.16e-2)" "unprognostic (3.42e-2)" "unprognostic (2.22e-1)" "unprognostic (9.44e-2)" "potential prognostic unfavorable (1.50e-10)" "unprognostic (3.34e-1)" "unprognostic (2.01e-3)" "potential prognostic unfavorable (1.35e-5)" "unprognostic (2.69e-2)" "unprognostic (2.55e-1)" "unprognostic (3.62e-2)" "unprognostic (1.56e-1)" "unprognostic (2.12e-1)" "unprognostic (1.95e-1)" "unprognostic (1.21e-1)" "unprognostic (1.44e-2)" "potential prognostic unfavorable (3.52e-4)" "unprognostic (7.93e-2)" "unprognostic (1.05e-1)" "unprognostic (1.47e-1)" "unprognostic (4.19e-3)" "unprognostic (2.62e-2)" "unprognostic (3.93e-1)" "unprognostic (2.77e-2)" "unprognostic (6.51e-2)" GTPBP3 "FLJ14700, GTPBG3, MSS1, MTGP1, THDF1" ENSG00000130299 "GTP binding protein 3, mitochondrial" Q969Y2 19 17334920-17342731 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "tRNA processing" Hydrolase "Cardiomyopathy, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA042158 Approved Supported Mitochondria NA NA "Cluster 18: Non-specific - Translation" "Cluster 24: Non-specific - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 20 Mitochondria "HPA042158: " "unprognostic (9.51e-3)" "unprognostic (2.71e-1)" "unprognostic (5.02e-2)" "unprognostic (2.63e-2)" "unprognostic (4.68e-2)" "unprognostic (8.20e-2)" "unprognostic (2.12e-1)" "unprognostic (3.27e-2)" "unprognostic (2.11e-2)" "unprognostic (1.09e-2)" "potential prognostic unfavorable (5.52e-5)" "unprognostic (3.28e-2)" "unprognostic (4.59e-2)" "validated prognostic unfavorable (8.12e-5)" "validated prognostic unfavorable (6.78e-4)" "unprognostic (3.44e-1)" "unprognostic (6.94e-2)" "unprognostic (6.28e-2)" "unprognostic (8.88e-3)" "unprognostic (5.11e-2)" "unprognostic (1.35e-2)" "unprognostic (1.33e-1)" "unprognostic (8.56e-2)" "potential prognostic unfavorable (4.51e-4)" "unprognostic (9.17e-3)" "unprognostic (7.44e-3)" "unprognostic (2.34e-2)" "unprognostic (2.05e-2)" "unprognostic (2.54e-1)" "unprognostic (1.09e-1)" "unprognostic (3.62e-1)" GTPBP4 "CRFG, FLJ10686, FLJ10690, NGB, NOG1" ENSG00000107937 "GTP binding protein 4" Q9BZE4 10 988434-1019932 "Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039618, HPA056468" Uncertain Supported "Nuclear membrane,Nucleoli,Nucleoli rim" No No 56000 "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 52: Non-specific - Mitochondria" "Cluster 17: Non-specific - RNA processing" 134 "Nucleoli, Nucleoli rim" "Nuclear membrane" "HPA039618: , HPA056468: " "unprognostic (7.06e-2)" "potential prognostic unfavorable (9.90e-4)" "unprognostic (1.31e-1)" "unprognostic (3.43e-3)" "unprognostic (2.48e-1)" "unprognostic (1.02e-1)" "unprognostic (4.91e-2)" "potential prognostic favorable (5.45e-6)" "unprognostic (5.04e-3)" "unprognostic (6.08e-2)" "unprognostic (6.09e-2)" "unprognostic (1.03e-1)" "potential prognostic unfavorable (3.81e-4)" "validated prognostic unfavorable (7.06e-10)" "validated prognostic unfavorable (5.01e-6)" "unprognostic (2.81e-2)" "unprognostic (8.65e-3)" "unprognostic (2.89e-1)" "unprognostic (1.08e-1)" "unprognostic (1.02e-1)" "unprognostic (1.37e-1)" "unprognostic (3.05e-2)" "potential prognostic unfavorable (2.29e-6)" "unprognostic (3.92e-2)" "unprognostic (1.10e-1)" "unprognostic (4.75e-1)" "unprognostic (1.33e-1)" "unprognostic (1.03e-1)" "unprognostic (1.28e-1)" "unprognostic (5.06e-2)" "unprognostic (9.16e-2)" GTPBP6 "FLJ20977, PGPL" ENSG00000178605 "GTP binding protein 6 (putative)" O43824 X 304529-318796 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA013336, CAB034924, HPA035467, HPA055418" Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 24: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 36: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 5 Mitochondria Nucleoplasm "CAB034924: , HPA013336: , HPA035467: , HPA055418: " "unprognostic (1.56e-2)" "unprognostic (3.49e-1)" "unprognostic (1.76e-2)" "unprognostic (7.32e-3)" "unprognostic (1.91e-1)" "unprognostic (1.89e-2)" "unprognostic (1.71e-2)" "unprognostic (4.58e-2)" "potential prognostic favorable (6.03e-5)" "unprognostic (1.16e-2)" "unprognostic (8.98e-2)" "potential prognostic unfavorable (3.61e-4)" "unprognostic (2.09e-1)" "unprognostic (2.06e-1)" "unprognostic (2.01e-1)" "unprognostic (1.58e-1)" "unprognostic (1.33e-1)" "potential prognostic favorable (5.70e-4)" "unprognostic (1.22e-3)" "unprognostic (2.21e-2)" "unprognostic (1.44e-1)" "unprognostic (1.65e-1)" "unprognostic (9.42e-2)" "unprognostic (7.37e-2)" "unprognostic (1.95e-2)" "unprognostic (1.55e-1)" "unprognostic (4.25e-1)" "unprognostic (5.70e-2)" GTPBP8 HSPC135 ENSG00000163607 "GTP binding protein 8 (putative)" Q8N3Z3 3 112990984-113015060 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 140.8;Late primary spermatocytes: 151.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034831, HPA058631" Approved Enhanced Mitochondria No No "Cluster 3: Non-specific - Nuclear processes" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 17: Non-specific - RNA processing" 1 Mitochondria "HPA034831: , HPA058631: " "unprognostic (1.10e-1)" "unprognostic (1.07e-1)" "unprognostic (2.65e-2)" "unprognostic (4.99e-2)" "unprognostic (8.29e-2)" "unprognostic (1.23e-1)" "unprognostic (4.90e-2)" "unprognostic (1.09e-2)" "unprognostic (9.43e-2)" "unprognostic (7.06e-3)" "potential prognostic favorable (2.09e-6)" "unprognostic (2.44e-2)" "unprognostic (1.73e-1)" "potential prognostic unfavorable (2.94e-4)" "unprognostic (2.27e-3)" "unprognostic (1.45e-3)" "unprognostic (1.55e-1)" "unprognostic (3.16e-1)" "unprognostic (2.03e-1)" "unprognostic (2.43e-2)" "unprognostic (8.18e-2)" "unprognostic (2.04e-2)" "unprognostic (5.86e-2)" "unprognostic (2.05e-2)" "unprognostic (4.91e-2)" "unprognostic (7.61e-2)" "unprognostic (1.13e-1)" "unprognostic (2.01e-1)" "unprognostic (1.44e-1)" "unprognostic (2.20e-1)" "unprognostic (1.55e-2)" GTSE1 "B99, GTSE-1, Lnc_bc060912" ENSG00000075218 "G2 and S-phase expressed 1" Q9NYZ3 22 46296870-46330810 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 10.5;lymphoid tissue: 18.2;testis: 7.1" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 49.4;Early primary spermatocytes: 71.6;Enteric transient amplifying cells: 43.5;Erythrocyte progenitors: 65.6;Esophageal basal cells: 32.4;Extravillous trophoblasts: 40.4;Gastric progenitor cells: 35.9;Hofbauer cells: 42.5;Late primary spermatocytes: 42.0;Megakaryocyte progenitors: 68.4;Migrating cytotrophoblasts: 33.8;Monocyte progenitors: 158.1;Neutrophil progenitors: 52.0" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA029457 Supported "Nucleoplasm,Plasma membrane,Primary cilium,Primary cilium tip,Centrosome,Basal body,Cytosol" Yes Yes "Cluster 15: NK-cells - Unknown function" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 6: Non-specific - Immune response" "Cluster 66: Non-specific - Mitochondria" "Cluster 27: Non-specific - Cell proliferation" 21 "Plasma membrane, Centrosome" "Nucleoplasm, Primary cilium, Primary cilium tip, Basal body, Cytosol" "HPA029457: " "unprognostic (1.25e-2)" "unprognostic (2.89e-1)" "potential prognostic favorable (7.05e-5)" "unprognostic (2.74e-1)" "unprognostic (2.10e-2)" "unprognostic (9.93e-2)" "unprognostic (1.19e-1)" "unprognostic (3.71e-2)" "unprognostic (6.60e-2)" "potential prognostic unfavorable (1.69e-4)" "validated prognostic unfavorable (1.96e-8)" "validated prognostic unfavorable (8.71e-7)" "potential prognostic unfavorable (1.77e-8)" "validated prognostic unfavorable (2.08e-8)" "validated prognostic unfavorable (1.20e-5)" "validated prognostic unfavorable (4.82e-6)" "validated prognostic unfavorable (4.23e-4)" "unprognostic (1.10e-1)" "unprognostic (1.09e-3)" "unprognostic (5.38e-2)" "unprognostic (3.05e-2)" "potential prognostic unfavorable (2.28e-5)" "unprognostic (1.39e-2)" "unprognostic (3.12e-3)" "unprognostic (1.84e-2)" "unprognostic (1.09e-1)" "unprognostic (1.03e-1)" "unprognostic (3.20e-2)" "unprognostic (4.77e-1)" "unprognostic (1.54e-1)" GTSF1 "Cue110, FAM112B, FLJ32942" ENSG00000170627 "Gametocyte specific factor 1" Q8WW33 12 54455950-54473602 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "testis: 173.7" "Group enriched" "Detected in many" 6 "Early spermatids: 1127.5;Late primary spermatocytes: 1287.0;Late spermatids: 2935.0;Oocytes: 764.4" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 1.5" "Cancer enriched" "Detected in many" 5 "Testicular Germ Cell Tumor (TCGA): 85.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 103.7;lymphoma: 115.5;Myeloma: 100.4" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA038876, HPA038877" Approved Approved Nucleoplasm NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 6: Testis - Spermatogenesis" "Cluster 11: White matter - Signal transduction" "Cluster 55: Lymphoma - Immune response" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 1 Nucleoplasm "HPA038876: , HPA038877: " "unprognostic (2.80e-3)" "unprognostic (5.91e-2)" "unprognostic (6.87e-2)" "unprognostic (4.22e-2)" "unprognostic (1.68e-1)" "unprognostic (1.85e-1)" "unprognostic (1.57e-1)" "unprognostic (4.99e-2)" "unprognostic (9.80e-3)" "unprognostic (6.13e-2)" "unprognostic (3.40e-1)" "unprognostic (1.18e-2)" "unprognostic (2.62e-2)" "unprognostic (3.99e-3)" "unprognostic (1.67e-1)" "unprognostic (1.57e-1)" "unprognostic (7.86e-2)" "unprognostic (2.32e-1)" "unprognostic (1.37e-1)" "unprognostic (1.99e-1)" "unprognostic (2.93e-1)" "unprognostic (1.73e-1)" "unprognostic (2.74e-3)" "unprognostic (1.67e-1)" "unprognostic (9.03e-2)" GTSF1L "C20orf65, dJ1028D15.4, FAM112A" ENSG00000124196 "Gametocyte specific factor 1 like" Q9H1H1 20 43726164-43727002 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 148 "testis: 210.9" "Group enriched" "Detected in some" 6 "Early spermatids: 3312.9;Late spermatids: 5894.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 5 "T-reg: 4.0" "Lineage enriched" "Detected in single" 5 "T-cells: 4.0" "Not detected" "Not detected" "Testis - Late spermatids" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA054694 Enhanced Uncertain Nucleoli NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 23: Testis - Spermatogenesis" "Cluster 55: Lymphoma - Immune response" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 1 Nucleoli "HPA054694: " GUCA1A "C6orf131, COD3, CORD14, dJ139D8.6, GCAP, GCAP1, GUCA, GUCA1" ENSG00000048545 "Guanylate cyclase activator 1A" P43080 6 42173364-42181338 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 42 "retina: 703.2" "Group enriched" "Detected in some" 5 "Cone photoreceptor cells: 53.8;Rod photoreceptor cells: 37.9" "Cell type enhanced" "Detected in some" "splatter: 3.4" "Cancer enriched" "Detected in some" 4 "Testicular Germ Cell Tumor (TCGA): 7.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "plasmacytoid DC: 4.9" "Lineage enriched" "Detected in single" 7 "dendritic cells: 4.9" "Cancer enhanced" "Detected in some" "Brain cancer: 1.7;lymphoma: 1.2;Neuroblastoma: 1.7" "Testis - Late spermatids" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA005561, HPA075056" Supported Uncertain "Plasma membrane" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 42: Retina - Visual perception" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 1: Neuronal - Visual perception" "Cluster 79: Photoreceptor cells - Phototransduction" 7 "Plasma membrane" "HPA005561: , HPA075056: " "unprognostic (9.29e-2)" "unprognostic (4.14e-2)" "unprognostic (1.62e-1)" GUCA1ANB ENSG00000287363 "GUCA1A neighbor" X6R8D5 6 42155406-42163418 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 720 "testis: 113.7" "Group enriched" "Detected in some" 14 "Early spermatids: 1.0;Late spermatids: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 28: Non-specific - Nuclear processes" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" GUCA1B "GCAP2, RP48" ENSG00000112599 "Guanylate cyclase activator 1B" Q9UMX6 6 42183284-42194956 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Sensory transduction, Vision" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 79 "retina: 432.4" "Group enriched" "Detected in many" 37 "Cone photoreceptor cells: 1039.2;Rod photoreceptor cells: 435.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA055479 Enhanced Approved "Nucleoplasm,Nuclear membrane,Microtubules,Primary cilium,Basal body" NA NA "Cluster 42: Retina - Visual perception" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" "Microtubules, Primary cilium" "Nucleoplasm, Nuclear membrane, Basal body" "HPA055479: " "unprognostic (1.19e-1)" "unprognostic (3.01e-1)" "unprognostic (1.09e-1)" "unprognostic (2.08e-1)" "unprognostic (1.31e-2)" "potential prognostic favorable (1.22e-4)" "unprognostic (1.93e-2)" "unprognostic (6.76e-2)" "unprognostic (6.33e-2)" "unprognostic (1.09e-1)" "unprognostic (5.45e-2)" "unprognostic (1.22e-1)" "unprognostic (2.67e-3)" GUCA1C GCAP3 ENSG00000138472 "Guanylate cyclase activator 1C" O95843 3 108907792-108953879 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "retina: 274.8" "Cell type enriched" "Detected in some" 12 "Cone photoreceptor cells: 596.2" "Group enriched" "Detected in some" 6 "deep-layer corticothalamic and 6b: 7.7;hippocampal CA4: 27.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 14 "Kidney cancer: 6.9" "Heart muscle - Cardiomyocytes, Stomach - Parietal cells, Testis - Early spermatids, Testis - Late spermatids" HPA041597 Uncertain Approved "Focal adhesion sites" NA NA "Cluster 42: Retina - Visual perception" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 79: Photoreceptor cells - Phototransduction" 2 "Focal adhesion sites" "HPA041597: " GUCA2A "GUCA2, STARA" ENSG00000197273 "Guanylate cyclase activator 2A" Q02747 1 42162690-42164745 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 60 "intestine: 969.2" "Group enriched" "Detected in some" 8 "Colonocytes: 5337.3;Enterocytes: 12561.5" "Not detected" "Not detected" "Group enriched" "Detected in many" 8 "Bladder Urothelial Carcinoma (TCGA): 18.7;Colon Adenocarcinoma (TCGA): 39.7;Rectum Adenocarcinoma (TCGA): 55.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "colorectal cancer: 11.2" "Colon - Colon enterocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA018215 Enhanced "Secreted to blood" "No annotated function" NA NA 8700000 "Cluster 77: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 9 "HPA018215: " "unprognostic (3.56e-1)" "unprognostic (2.55e-3)" "unprognostic (4.01e-1)" "unprognostic (1.04e-1)" "unprognostic (8.47e-3)" "unprognostic (1.26e-1)" "unprognostic (1.79e-1)" "unprognostic (1.18e-1)" "unprognostic (1.77e-2)" "unprognostic (5.27e-2)" "unprognostic (1.99e-1)" GUCA2B ENSG00000044012 "Guanylate cyclase activator 2B" Q16661 1 42153410-42155820 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "intestine: 138.2" "Group enriched" "Detected in some" 7 "Colonocytes: 1492.9;Enterocytes: 3100.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 6.3;Liver Hepatocellular Carcinoma (TCGA): 9.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 24 "colorectal cancer: 16.5" "Colon - Colon enterocytes, Skin - Keratinocyte (granular), Stomach - Parietal cells" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.3" "Secreted to blood" "No annotated function" NA NA 77700 900000 "Cluster 40: Monocytes - Innate immune response" "Cluster 77: Intestine - Digestion" "Cluster 40: Non-specific - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 2 "unprognostic (8.38e-2)" "unprognostic (9.38e-2)" "potential prognostic favorable (9.37e-4)" "unprognostic (3.24e-3)" "unprognostic (3.72e-1)" "unprognostic (1.86e-2)" "unprognostic (2.33e-2)" "unprognostic (5.05e-2)" "unprognostic (1.32e-1)" "unprognostic (2.53e-1)" "unprognostic (2.52e-2)" "unprognostic (1.58e-1)" GUCD1 "C22orf13, LLN4, MGC1842" ENSG00000138867 "Guanylyl cyclase domain containing 1" Q96NT3 22 24540423-24555935 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 154.7;Erythrocyte progenitors: 89.8;Hepatocytes: 196.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022786 Approved Nucleoplasm NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 6 Nucleoplasm "HPA022786: " "unprognostic (2.04e-2)" "unprognostic (9.12e-2)" "unprognostic (5.74e-2)" "unprognostic (1.20e-1)" "unprognostic (9.23e-2)" "unprognostic (2.32e-1)" "unprognostic (2.86e-2)" "unprognostic (2.32e-1)" "unprognostic (3.20e-2)" "potential prognostic favorable (8.59e-5)" "unprognostic (2.44e-3)" "unprognostic (5.86e-3)" "unprognostic (5.40e-2)" "unprognostic (1.96e-1)" "unprognostic (8.59e-2)" "unprognostic (6.69e-2)" "unprognostic (1.52e-1)" "unprognostic (1.35e-1)" "unprognostic (2.98e-1)" "unprognostic (3.70e-2)" "unprognostic (2.01e-1)" "unprognostic (9.62e-2)" "unprognostic (5.97e-3)" "unprognostic (2.57e-1)" "unprognostic (2.11e-2)" "unprognostic (2.15e-1)" "unprognostic (2.13e-1)" "unprognostic (4.10e-2)" "unprognostic (8.81e-2)" GUCY1A1 "GC-SA3, GUC1A3, GUCY1A3" ENSG00000164116 "Guanylate cyclase 1 soluble subunit alpha 1" Q02108 4 155666726-155737059 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "cGMP biosynthesis" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 212.4;Hematopoietic stem cells: 538.6;Pericytes: 288.1;Prostatic glandular cells: 549.7;Retinal bipolar cells: 281.2;Thymocytes: 219.4;Vascular smooth muscle cells: 367.1" "Cell type enhanced" "Detected in all" "midbrain-derived inhibitory: 584.0" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 48.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 8.3;non-classical monocyte: 10.1;plasmacytoid DC: 11.5" "Group enriched" "Detected in many" 35 "dendritic cells: 11.5;monocytes: 10.1;NK-cells: 8.3" "Cancer enhanced" "Detected in many" "prostate cancer: 29.1" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Pituitary gland - Fibroblasts, Spleen - Fibroblasts_1, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010887, HPA056004, HPA058617" Uncertain Supported Nucleoplasm NA NA 11000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 35: Non-specific - Mixed function" "Cluster 33: Neurons - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 110: Mural cells - ECM organization" 2 Nucleoplasm "CAB010887: , HPA056004: , HPA058617: " "unprognostic (3.45e-2)" "unprognostic (8.61e-2)" "unprognostic (9.27e-3)" "unprognostic (6.29e-2)" "unprognostic (7.79e-2)" "unprognostic (1.33e-1)" "unprognostic (8.83e-3)" "unprognostic (7.31e-3)" "unprognostic (3.93e-3)" "validated prognostic favorable (1.33e-6)" "validated prognostic favorable (4.13e-6)" "unprognostic (8.26e-2)" "unprognostic (2.64e-1)" "potential prognostic favorable (5.94e-4)" "unprognostic (2.65e-1)" "unprognostic (8.38e-2)" "unprognostic (7.93e-3)" "unprognostic (6.44e-3)" "unprognostic (2.44e-1)" "unprognostic (2.00e-1)" "unprognostic (9.77e-2)" "unprognostic (1.61e-1)" "unprognostic (1.24e-1)" "potential prognostic favorable (4.77e-4)" "unprognostic (1.41e-1)" "unprognostic (1.29e-2)" "unprognostic (1.74e-3)" "unprognostic (9.73e-2)" "unprognostic (2.56e-1)" GUCY1A2 "GC-SA2, GUC1A2" ENSG00000152402 "Guanylate cyclase 1 soluble subunit alpha 2" P33402 11 106674019-107018476 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "cGMP biosynthesis" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 16.8" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 277.2;Brain inhibitory neurons: 410.7;Gonadotrophs: 180.1;Granulosa cells: 257.9;Oligodendrocyte progenitor cells: 267.5;Other brain neurons: 167.3;Pancreatic duct cells: 120.6;Pericytes: 487.8;Pituicytes/FSCs: 313.1;Retinal amacrine cells: 175.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adrenal gland - Fibroblasts, Breast - Endothelial cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Spleen - Fibroblasts_1, Testis - Peritubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB009534 Uncertain NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 110: Mural cells - ECM organization" 4 "CAB009534: " "unprognostic (7.71e-2)" "unprognostic (5.77e-2)" "unprognostic (6.48e-2)" "unprognostic (7.75e-2)" "unprognostic (3.14e-2)" "potential prognostic favorable (6.74e-4)" "unprognostic (1.53e-3)" "unprognostic (6.45e-2)" "unprognostic (1.33e-1)" "unprognostic (1.15e-1)" "unprognostic (3.59e-2)" "unprognostic (1.99e-1)" "unprognostic (1.29e-1)" "unprognostic (2.55e-1)" GUCY1B1 "GC-S-beta-1, GC-SB3, GUC1B3, GUCY1B3" ENSG00000061918 "Guanylate cyclase 1 soluble subunit beta 1" Q02153 4 155758992-155807811 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "cGMP biosynthesis" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 125.3;Hematopoietic stem cells: 111.1;Megakaryocyte progenitors: 136.9;Megakaryocytes: 717.1;Pericytes: 169.2;Platelets: 535.8;Retinal bipolar cells: 86.9;Vascular smooth muscle cells: 134.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "intermediate monocyte: 7.2;non-classical monocyte: 24.0" "Lineage enriched" "Detected in many" 13 "monocytes: 24.0" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells, Liver - Hepatic stellate cells, Prostate - Smooth muscle cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010890, HPA020870, HPA077706" Approved Approved Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 73: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 55: Lymphoma - Immune response" "Cluster 110: Mural cells - ECM organization" 6 Cytosol "CAB010890: , HPA020870: , HPA077706: " "unprognostic (2.17e-2)" "unprognostic (1.71e-1)" "unprognostic (3.00e-1)" "unprognostic (1.29e-2)" "unprognostic (1.13e-1)" "unprognostic (7.26e-3)" "unprognostic (1.32e-2)" "unprognostic (1.28e-2)" "unprognostic (2.37e-1)" "validated prognostic favorable (4.35e-4)" "validated prognostic favorable (9.04e-5)" "potential prognostic unfavorable (7.61e-4)" "unprognostic (1.02e-1)" "unprognostic (3.71e-3)" "unprognostic (7.76e-3)" "unprognostic (2.65e-1)" "unprognostic (7.32e-3)" "unprognostic (8.45e-2)" "unprognostic (6.21e-2)" "unprognostic (1.03e-1)" "unprognostic (2.71e-1)" "unprognostic (5.46e-1)" "unprognostic (6.39e-2)" "unprognostic (1.80e-2)" "potential prognostic unfavorable (8.98e-6)" "unprognostic (5.30e-3)" "unprognostic (1.67e-2)" "unprognostic (1.68e-1)" "unprognostic (5.69e-2)" GUCY2C "GUC2C, STAR" ENSG00000070019 "Guanylate cyclase 2C" P25092 12 14612632-14696599 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "cGMP biosynthesis" "Lyase, Receptor" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "intestine: 64.2" "Cell type enhanced" "Detected in many" "Adipocytes: 64.2;Cardiomyocytes: 472.7;Colonocytes: 126.0;Enteric stem cells: 118.7;Enteric transient amplifying cells: 115.8;Enterocytes: 218.7;Goblet cells: 129.7;Neuroendocrine cells: 445.2;Paneth cells: 131.5" "Cell type enriched" "Detected in many" 7 "choroid plexus epithelial cell: 50.8" "Group enriched" "Detected in many" 6 "Colon Adenocarcinoma (TCGA): 34.1;Rectum Adenocarcinoma (TCGA): 37.9;Stomach Adenocarcinoma (TCGA): 13.3" "Region enriched" "Detected in many" 4 "choroid plexus: 6.8" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.5" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 7 "Bile duct cancer: 10.5;colorectal cancer: 17.5;Gastric cancer: 7.2" "Colon - Colon enterocytes" "Region enhanced" "Detected in some" "midbrain: 1.8" "Low region specificity" "Detected in many" "HPA037655, HPA073759" Uncertain Uncertain Vesicles NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 8: Immune cells - Immune response" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" 1 Vesicles "HPA037655: , HPA073759: " "unprognostic (6.14e-2)" "unprognostic (1.25e-2)" "unprognostic (4.01e-3)" "validated prognostic unfavorable (1.31e-5)" "validated prognostic unfavorable (9.46e-6)" "unprognostic (3.77e-2)" "unprognostic (5.29e-2)" "unprognostic (8.45e-2)" "unprognostic (8.33e-2)" "unprognostic (1.99e-1)" "unprognostic (2.03e-3)" "unprognostic (1.83e-2)" "unprognostic (1.10e-1)" "unprognostic (3.57e-1)" GUCY2D "CORD6, CYGD, GUC1A4, GUC2D, LCA, LCA1, retGC, RETGC-1, ROS-GC1" ENSG00000132518 "Guanylate cyclase 2D, retinal" Q02846 17 8002615-8020342 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "cGMP biosynthesis, Sensory transduction, Vision" Lyase "Cone-rod dystrophy, Congenital stationary night blindness, Disease variant, Leber congenital amaurosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "retina: 31.7" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 82.8;Early spermatids: 24.9;Esophageal suprabasal cells: 15.2;Late spermatids: 32.3;pDCs: 27.5;Retinal ganglion cells: 15.5;Rod photoreceptor cells: 152.2" "Cell type enhanced" "Detected in some" "deep-layer near-projecting: 2.1;lower rhombic lip: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 31 "plasmacytoid DC: 8.0" "Lineage enriched" "Detected in single" 50 "dendritic cells: 8.0" "Cancer enhanced" "Detected in single" "prostate cancer: 1.1" "Prostate - Prostate glandular cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 42: Retina - Visual perception" "Cluster 1: Neuronal - Visual perception" "Cluster 79: Photoreceptor cells - Phototransduction" 1 GUCY2F "CYGF, GC-F, GUC2DL, RetGC-2, ROS-GC2" ENSG00000101890 "Guanylate cyclase 2F, retinal" P51841 X 109372906-109482086 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "cGMP biosynthesis, Sensory transduction, Vision" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 143 "retina: 39.1" "Cell type enriched" "Detected in some" 14 "Rod photoreceptor cells: 136.8" "Cell type enriched" "Detected in some" 8 "fibroblast: 24.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Rhabdoid: 1.0" "Pituitary gland - Thyrotropes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in single" "Not detected" "Not detected" NA NA "Cluster 42: Retina - Visual perception" "Cluster 5: Rhabdoid - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" GUF1 FLJ13220 ENSG00000151806 "GTP binding elongation factor GUF1" Q8N442 4 44678420-44700928 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein biosynthesis" Hydrolase "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003934, HPA024222" Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 17: Non-specific - RNA processing" 4 "Nucleoplasm, Mitochondria" "HPA003934: , HPA024222: " "unprognostic (6.23e-2)" "unprognostic (2.81e-2)" "unprognostic (3.61e-1)" "unprognostic (4.28e-2)" "unprognostic (3.35e-2)" "unprognostic (7.35e-2)" "unprognostic (1.29e-1)" "unprognostic (2.36e-2)" "unprognostic (1.95e-1)" "unprognostic (5.52e-2)" "potential prognostic favorable (9.72e-6)" "unprognostic (1.47e-2)" "unprognostic (2.74e-1)" "unprognostic (2.53e-1)" "unprognostic (1.61e-2)" "unprognostic (1.16e-1)" "unprognostic (4.84e-3)" "unprognostic (2.55e-1)" "unprognostic (6.43e-2)" "unprognostic (9.96e-2)" "unprognostic (1.61e-1)" "unprognostic (1.04e-1)" "unprognostic (3.93e-2)" "unprognostic (8.19e-2)" "unprognostic (7.26e-3)" "unprognostic (3.18e-2)" "unprognostic (5.73e-3)" "potential prognostic favorable (1.89e-4)" "unprognostic (2.22e-1)" "unprognostic (2.00e-2)" "unprognostic (7.90e-2)" GUK1 ENSG00000143774 "Guanylate kinase 1" Q16774 1 228139962-228148984 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 463.7" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 2579.8;Esophageal suprabasal cells: 2046.9;Late spermatids: 1060.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048587 Approved Approved "Golgi apparatus,Plasma membrane" NA NA 38000 "Cluster 45: Eosinophils - Unknown function" "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 85: Squamous epithelial cells - Keratinization" 1 "Plasma membrane" "Golgi apparatus" "HPA048587: " "unprognostic (3.83e-1)" "unprognostic (2.44e-1)" "unprognostic (2.93e-1)" "unprognostic (8.24e-2)" "unprognostic (1.68e-1)" "unprognostic (3.13e-1)" "unprognostic (1.06e-2)" "unprognostic (4.09e-1)" "unprognostic (6.91e-2)" "unprognostic (1.05e-2)" "unprognostic (1.73e-2)" "unprognostic (2.05e-2)" "unprognostic (2.80e-1)" "unprognostic (1.71e-3)" "unprognostic (2.63e-1)" "unprognostic (2.05e-2)" "unprognostic (3.41e-2)" "unprognostic (5.18e-2)" "unprognostic (1.71e-1)" "unprognostic (1.18e-1)" "unprognostic (1.59e-1)" "unprognostic (4.41e-2)" "unprognostic (1.18e-1)" "unprognostic (2.34e-1)" "unprognostic (3.10e-2)" "unprognostic (2.64e-1)" "unprognostic (5.24e-2)" "unprognostic (3.79e-1)" "unprognostic (1.48e-1)" "unprognostic (5.17e-2)" "unprognostic (2.67e-1)" GULP1 "CED-6, CED6, GULP" ENSG00000144366 "GULP PTB domain containing engulfment adaptor 1" Q9UBP9 2 188291669-188595931 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Lipid transport, Phagocytosis, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 77.9" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 1426.0;Pancreatic acinar cells: 480.0;Podocytes: 819.5;Retinal pigment epithelial cells: 810.0;Syncytiotrophoblasts: 860.5" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 1386.4;lower rhombic lip: 920.1;midbrain-derived inhibitory: 1053.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020587 Enhanced Approved Vesicles NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 9 Vesicles "HPA020587: " "unprognostic (1.73e-1)" "unprognostic (3.45e-1)" "unprognostic (3.14e-2)" "unprognostic (1.65e-1)" "potential prognostic unfavorable (2.95e-4)" "unprognostic (3.62e-2)" "unprognostic (4.41e-2)" "unprognostic (2.85e-2)" "unprognostic (2.85e-1)" "unprognostic (6.51e-3)" "potential prognostic favorable (3.38e-4)" "unprognostic (1.21e-3)" "unprognostic (8.26e-2)" "unprognostic (1.41e-3)" "unprognostic (1.81e-1)" "unprognostic (3.19e-2)" "unprognostic (5.30e-2)" "unprognostic (2.92e-1)" "unprognostic (1.06e-1)" "unprognostic (8.38e-3)" "unprognostic (2.91e-1)" "unprognostic (1.86e-2)" "unprognostic (1.80e-1)" "unprognostic (2.62e-1)" "unprognostic (1.74e-1)" "unprognostic (9.39e-3)" "unprognostic (3.06e-1)" "potential prognostic unfavorable (1.41e-4)" "unprognostic (1.76e-1)" "unprognostic (5.70e-2)" "unprognostic (9.81e-2)" GUSB ENSG00000169919 "Glucuronidase beta" P08236 7 65960684-65982215 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Cancer-related genes, Disease variant, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 157.3;Kupffer cells: 152.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036322, HPA036323" Approved Supported Vesicles "Intracellular and membrane" Enzyme NA NA 560000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 70: Non-specific - Protein processing" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 63: Non-specific - Protein processing" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 3 Vesicles "HPA036322: , HPA036323: " "unprognostic (3.12e-1)" "unprognostic (1.04e-1)" "unprognostic (2.72e-1)" "unprognostic (9.64e-2)" "unprognostic (2.48e-1)" "unprognostic (2.55e-3)" "unprognostic (1.85e-2)" "unprognostic (1.62e-3)" "unprognostic (1.56e-1)" "potential prognostic unfavorable (6.76e-4)" "potential prognostic favorable (8.02e-5)" "unprognostic (1.44e-1)" "unprognostic (4.40e-2)" "unprognostic (1.49e-1)" "unprognostic (4.04e-2)" "unprognostic (9.19e-3)" "unprognostic (7.99e-2)" "unprognostic (8.55e-2)" "unprognostic (6.15e-2)" "unprognostic (4.35e-2)" "unprognostic (5.20e-3)" "unprognostic (4.67e-2)" "unprognostic (1.65e-1)" "unprognostic (1.04e-1)" "unprognostic (8.39e-3)" "unprognostic (1.86e-2)" "unprognostic (4.24e-1)" "unprognostic (4.80e-2)" "unprognostic (2.30e-1)" "unprognostic (9.33e-2)" "unprognostic (1.34e-2)" GVQW3 ENSG00000179240 "GVQW motif containing 3" Q3ZCU0 11 76381303-76414619 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "retina: 13.2" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 31.9;Brain excitatory neurons: 30.6;Brain inhibitory neurons: 29.7;Rod photoreceptor cells: 35.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" HPA057405 Uncertain Approved "Nucleoplasm,Endoplasmic reticulum,Centrosome,Cytosol" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 42: Retina - Visual perception" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 24: Non-specific - Unknown function" "Cluster 109: Neurons - Neuronal signaling" "Nucleoplasm, Centrosome" "Endoplasmic reticulum, Cytosol" "HPA057405: " "unprognostic (1.25e-1)" "unprognostic (3.12e-1)" "unprognostic (1.06e-1)" "unprognostic (9.70e-3)" "unprognostic (1.16e-2)" "unprognostic (7.14e-2)" "unprognostic (6.58e-3)" "unprognostic (4.49e-3)" "unprognostic (1.29e-2)" "unprognostic (4.59e-3)" "unprognostic (1.64e-2)" "unprognostic (2.68e-1)" "unprognostic (2.48e-1)" "unprognostic (1.03e-2)" "unprognostic (3.38e-1)" "unprognostic (1.46e-1)" "unprognostic (6.19e-3)" "unprognostic (1.49e-2)" "unprognostic (2.63e-1)" "potential prognostic favorable (5.24e-5)" "unprognostic (1.02e-2)" "unprognostic (5.84e-2)" "unprognostic (2.04e-2)" "unprognostic (4.02e-1)" "unprognostic (2.48e-1)" GXYLT1 "FLJ43151, GLT8D3" ENSG00000151233 "Glucoside xylosyltransferase 1" Q4G148 12 42081845-42144874 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077997 Approved "Endoplasmic reticulum,Vesicles" "Intracellular and membrane" Enzyme NA NA 790000 "Cluster 25: Non-specific - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 44: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 3 "Endoplasmic reticulum" Vesicles "HPA077997: " "unprognostic (1.24e-1)" "unprognostic (2.11e-3)" "unprognostic (2.71e-1)" "unprognostic (3.72e-2)" "unprognostic (1.25e-1)" "unprognostic (2.73e-2)" "unprognostic (2.42e-1)" "potential prognostic unfavorable (9.79e-4)" "unprognostic (7.77e-2)" "unprognostic (5.30e-3)" "potential prognostic favorable (6.86e-4)" "unprognostic (3.64e-2)" "unprognostic (3.60e-2)" "unprognostic (5.91e-3)" "unprognostic (2.79e-2)" "unprognostic (2.67e-3)" "unprognostic (2.33e-2)" "unprognostic (5.29e-3)" "unprognostic (9.64e-2)" "unprognostic (1.05e-1)" "unprognostic (3.85e-3)" "unprognostic (5.96e-2)" "unprognostic (1.61e-3)" "unprognostic (1.12e-1)" "unprognostic (2.98e-1)" "unprognostic (6.49e-2)" "unprognostic (4.04e-2)" "unprognostic (2.46e-1)" "unprognostic (5.01e-1)" "unprognostic (5.35e-2)" "unprognostic (4.27e-2)" GXYLT2 GLT8D4 ENSG00000172986 "Glucoside xylosyltransferase 2" A0PJZ3 3 72888046-72998138 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 115.4;Fibro-adipogenic progenitors: 112.0;Medullary thymic epithelial cells: 120.0;Mesothelial cells: 189.1;Myosatellite cells: 203.1" "Cell type enhanced" "Detected in many" "fibroblast: 125.4;oligodendrocyte: 121.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells, Breast - Fibroblasts, Kidney - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA068429 Uncertain Approved "Nucleoplasm,Cytokinetic bridge,Midbody ring" Yes No "Cluster 2: Dendritic cells - Unknown function" "Cluster 35: Non-specific - Mixed function" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 108: Fibroblasts - ECM organization" Nucleoplasm "Cytokinetic bridge, Midbody ring" "HPA068429: " "unprognostic (2.87e-1)" "unprognostic (1.22e-2)" "unprognostic (3.86e-2)" "unprognostic (2.02e-2)" "unprognostic (1.14e-1)" "unprognostic (3.89e-1)" "unprognostic (1.87e-2)" "unprognostic (1.16e-2)" "unprognostic (4.81e-2)" "unprognostic (7.42e-3)" "unprognostic (2.81e-3)" "unprognostic (1.59e-1)" "unprognostic (1.63e-2)" "unprognostic (2.37e-1)" "unprognostic (1.61e-2)" "unprognostic (9.67e-2)" "unprognostic (6.89e-3)" "unprognostic (1.63e-2)" "unprognostic (3.78e-2)" "unprognostic (2.14e-1)" "unprognostic (3.42e-1)" "unprognostic (1.30e-1)" "unprognostic (1.16e-1)" "unprognostic (1.68e-2)" "unprognostic (4.61e-2)" "potential prognostic unfavorable (6.30e-4)" "unprognostic (6.57e-2)" "unprognostic (4.44e-2)" "unprognostic (9.82e-2)" GYG1 GYG ENSG00000163754 "Glycogenin 1" P46976 3 148991408-149031775 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Glycogen biosynthesis" Transferase "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 535.2;tongue: 333.9" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 609.9;Late spermatids: 617.9;Neutrophil progenitors: 583.7;Neutrophils: 608.9;Oocytes: 1201.9" "Cell type enhanced" "Detected in all" "Bergmann glia: 169.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Prostate - Smooth muscle cells, Spleen - Neutrophils_2, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030497, HPA073229" Supported Approved Vesicles NA NA 100000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 13 Vesicles "HPA030497: , HPA073229: " "unprognostic (1.47e-1)" "unprognostic (2.58e-3)" "unprognostic (3.21e-1)" "unprognostic (9.93e-2)" "unprognostic (5.11e-2)" "unprognostic (9.23e-2)" "unprognostic (2.71e-2)" "unprognostic (2.18e-1)" "unprognostic (3.98e-2)" "potential prognostic unfavorable (1.08e-4)" "potential prognostic favorable (7.82e-6)" "unprognostic (4.29e-2)" "unprognostic (3.99e-2)" "potential prognostic unfavorable (4.20e-5)" "unprognostic (5.14e-3)" "unprognostic (2.74e-2)" "unprognostic (8.89e-3)" "unprognostic (4.76e-2)" "unprognostic (7.70e-2)" "unprognostic (1.14e-1)" "unprognostic (2.48e-2)" "unprognostic (9.94e-3)" "unprognostic (4.73e-2)" "unprognostic (8.88e-2)" "unprognostic (4.22e-2)" "unprognostic (4.29e-2)" "unprognostic (1.75e-1)" "unprognostic (3.98e-2)" "unprognostic (2.27e-1)" "unprognostic (1.74e-1)" "unprognostic (1.54e-1)" GYG2 GN-2 ENSG00000056998 "Glycogenin 2" O15488 X 2828822-2882820 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycogen biosynthesis" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 146.8;breast: 40.4" "Group enriched" "Detected in many" 7 "Adipocytes: 580.6;Ependymal cells: 201.9" "Cell type enhanced" "Detected in many" "astrocyte: 107.8;ependymal cell: 212.8" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 71.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 42.5;testis cancer: 54.4" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Lung - Respiratory ciliated cells, Skin - Adipocytes (Skin)" "Low region specificity" "Detected in all" "HPA005495, HPA064686" Enhanced Approved "Nucleoplasm,Nucleoli,Mitotic spindle,Centrosome,Cytosol" Yes No "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 44: Non-specific - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 89: Adipocytes - Lipid metabolism" 10 "Nucleoli, Cytosol" "Nucleoplasm, Mitotic spindle, Centrosome" "HPA005495: , HPA064686: " "unprognostic (6.03e-2)" "unprognostic (9.74e-2)" "unprognostic (5.37e-2)" "unprognostic (5.35e-2)" "unprognostic (8.22e-3)" "unprognostic (4.29e-2)" "unprognostic (4.07e-3)" "potential prognostic unfavorable (2.00e-4)" "unprognostic (3.37e-1)" "unprognostic (1.51e-2)" "unprognostic (1.18e-2)" "unprognostic (1.15e-2)" "unprognostic (1.61e-1)" "unprognostic (3.79e-1)" "unprognostic (6.11e-2)" "unprognostic (8.44e-2)" "unprognostic (3.27e-1)" "unprognostic (1.75e-1)" "potential prognostic favorable (6.32e-5)" "unprognostic (6.37e-2)" "unprognostic (1.27e-1)" "unprognostic (1.10e-3)" "unprognostic (9.49e-2)" "unprognostic (3.81e-2)" "unprognostic (1.80e-1)" "unprognostic (7.42e-2)" "unprognostic (3.34e-2)" "unprognostic (9.80e-2)" GYPA "CD235a, GPA, MN, MNS" ENSG00000170180 "Glycophorin A (MNS blood group)" P02724 4 144109303-144140751 "Blood group antigen proteins, CD markers, Predicted membrane proteins, Transporters" "Host-virus interaction" "Blood group antigen, Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 38 "bone marrow: 147.2" "Group enriched" "Detected in some" 36 "Erythrocyte progenitors: 235.2;Erythrocytes: 111.1" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 18 "Leukemia: 32.6" "Kidney - Proximal tubular cells, Liver - Erythroid cells, Lung - Neutrophils_1, Spleen - Erythrocytes" "CAB002658, HPA014811" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 2300000 "Cluster 15: Bone marrow - Innate immune response" "Cluster 53: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 27 "Nucleoplasm, Plasma membrane, Cytosol" "CAB002658: , HPA014811: " GYPB "CD235b, GPB, MNS, SS" ENSG00000250361 "Glycophorin B (MNS blood group)" P06028 4 143996104-144019380 "Blood group antigen proteins, CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Blood group antigen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "bone marrow: 59.4" "Group enriched" "Detected in some" 7 "Erythrocyte progenitors: 284.5;Erythrocytes: 177.0" "Cell type enhanced" "Detected in many" "upper-layer intratelencephalic: 10.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 149 "Leukemia: 17.3" "Liver - Erythroid cells, Spleen - Erythrocytes" "Intracellular and membrane" Other NA NA "Cluster 15: Bone marrow - Innate immune response" "Cluster 53: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 4 GYPC "CD236, CD236R, Ge, GPC, GYPD" ENSG00000136732 "Glycophorin C (Gerbich blood group)" P04921 2 126656133-126696667 "Blood group antigen proteins, CD markers, Predicted membrane proteins" "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 415.6" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 281.4;Erythrocyte progenitors: 730.9;Erythrocytes: 882.7;Hofbauer cells: 948.9;Lymphatic endothelial cells: 384.7;Melanocytes: 397.6;Plasma cells: 234.4" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 87.4;fibroblast: 71.2;leukocyte: 65.8;vascular associated smooth muscle cell: 43.7" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 387.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 222.8;skin cancer: 319.3" "Liver - Vascular endothelial cells, Pituitary gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008965, CAB009445" Enhanced Supported "Plasma membrane" NA NA 760000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 11 "Plasma membrane" "CAB009445: , HPA008965: " "unprognostic (8.65e-3)" "unprognostic (1.11e-2)" "unprognostic (7.03e-2)" "unprognostic (9.19e-2)" "unprognostic (5.64e-2)" "unprognostic (7.49e-2)" "unprognostic (9.16e-3)" "unprognostic (2.81e-3)" "unprognostic (3.00e-2)" "unprognostic (2.40e-1)" "potential prognostic favorable (2.09e-4)" "unprognostic (7.37e-3)" "unprognostic (1.90e-1)" "unprognostic (1.25e-1)" "unprognostic (3.16e-2)" "unprognostic (2.35e-2)" "unprognostic (5.42e-2)" "unprognostic (4.80e-2)" "unprognostic (9.28e-2)" "unprognostic (3.17e-2)" "unprognostic (1.61e-1)" "unprognostic (6.07e-2)" "unprognostic (4.32e-1)" "unprognostic (2.61e-1)" "unprognostic (6.10e-2)" "unprognostic (8.84e-2)" "unprognostic (1.11e-1)" "unprognostic (1.18e-2)" "unprognostic (1.48e-1)" "unprognostic (1.85e-1)" "unprognostic (1.53e-1)" GYPE "GPE, MNS" ENSG00000197465 "Glycophorin E (MNS blood group)" P15421 4 143870864-143905563 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 4 "bone marrow: 12.5" "Cell type enhanced" "Detected in some" "Adipocytes: 15.9;Cardiomyocytes: 42.9;Epicardial cells: 27.3;Erythrocyte progenitors: 74.0;Erythrocytes: 19.6;Hematopoietic stem cells: 11.6;Innate lymphoid cells: 12.9;Thymocytes: 23.7;Tuft cells: 11.5" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.2" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in some" 4 "Leukemia: 9.2" "Kidney - Fibroblasts, Prostate - Fibroblasts, Spleen - B-cells (Spleen)" NA NA "Cluster 15: Bone marrow - Innate immune response" "Cluster 53: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" "potential prognostic favorable (1.69e-5)" GYS1 "GSY, GYS" ENSG00000104812 "Glycogen synthase 1" P13807 19 48968130-48993310 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycogen biosynthesis" "Allosteric enzyme, Glycosyltransferase, Transferase" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "heart muscle: 112.2;skeletal muscle: 299.1;tongue: 188.4" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 161.5;Myonuclei: 323.3;Neutrophil progenitors: 200.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007793, HPA041598" Enhanced Approved Microtubules,Cytosol NA NA 38000 "Cluster 13: Non-specific - Mitochondria" "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 25: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 55 "Microtubules, Cytosol" "CAB007793: , HPA041598: " "unprognostic (4.32e-3)" "unprognostic (4.63e-2)" "unprognostic (1.31e-2)" "unprognostic (1.34e-1)" "unprognostic (6.17e-3)" "unprognostic (2.01e-2)" "unprognostic (1.29e-1)" "unprognostic (1.71e-2)" "unprognostic (6.19e-3)" "unprognostic (1.39e-2)" "unprognostic (2.42e-2)" "unprognostic (2.81e-2)" "unprognostic (9.21e-3)" "unprognostic (5.10e-3)" "unprognostic (9.67e-2)" "unprognostic (3.74e-2)" "unprognostic (5.07e-3)" "unprognostic (7.44e-2)" "unprognostic (4.80e-1)" "unprognostic (1.53e-2)" "unprognostic (1.60e-1)" "unprognostic (8.20e-2)" "unprognostic (2.72e-2)" "unprognostic (3.05e-2)" "unprognostic (1.09e-1)" "unprognostic (3.20e-1)" "unprognostic (1.14e-1)" "unprognostic (2.64e-2)" "unprognostic (1.80e-1)" "unprognostic (2.00e-2)" "unprognostic (3.16e-1)" GYS2 ENSG00000111713 "Glycogen synthase 2" P54840 12 21536107-21604847 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Glycogen biosynthesis" "Allosteric enzyme, Glycosyltransferase, Transferase" "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 31 "liver: 162.5" "Cell type enhanced" "Detected in some" "Astrocytes: 1.8;Bergmann glia: 2.2;Distal convoluted tubule cells: 1.2;Esophageal apical cells: 3.1;Hepatocytes: 8.8;Loop of henle epithelial cells: 2.3;Proximal tubule cells: 2.1;Renal connecting tubule cells: 1.4" "Low cell type specificity" "Detected in some" "Cancer enriched" "Detected in single" 150 "Liver Hepatocellular Carcinoma (TCGA): 15.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Liver - Hepatocytes, Skin - Adipocytes (Skin)" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA039482 Approved NA NA 16000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 7: Liver cancer - Metabolism" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 5 "HPA039482: " "validated prognostic favorable (4.66e-5)" "validated prognostic favorable (5.61e-5)" GZF1 "dJ322G13.2, ZBTB23, ZNF336" ENSG00000125812 "GDNF inducible zinc finger protein 1" Q9H116 20 23362182-23373062 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 42.9;Neutrophils: 39.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024520 Uncertain Supported Nucleoplasm,Nucleoli NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 103: Non-specific - Basic cellular processes" 6 "Nucleoplasm, Nucleoli" "HPA024520: " "unprognostic (7.20e-2)" "unprognostic (4.92e-2)" "unprognostic (5.87e-2)" "unprognostic (1.84e-2)" "unprognostic (2.79e-1)" "unprognostic (2.90e-2)" "unprognostic (1.23e-1)" "unprognostic (5.14e-2)" "unprognostic (1.20e-1)" "unprognostic (1.04e-1)" "unprognostic (1.61e-2)" "unprognostic (3.62e-1)" "unprognostic (2.06e-1)" "potential prognostic unfavorable (7.56e-5)" "unprognostic (2.62e-2)" "unprognostic (3.98e-2)" "unprognostic (3.54e-2)" "potential prognostic unfavorable (8.21e-4)" "unprognostic (1.66e-1)" "unprognostic (1.94e-1)" "unprognostic (1.66e-1)" "unprognostic (6.36e-2)" "unprognostic (6.42e-2)" "unprognostic (1.73e-1)" "unprognostic (1.05e-1)" "unprognostic (4.48e-2)" "unprognostic (1.78e-1)" "unprognostic (7.90e-2)" "unprognostic (3.47e-1)" "potential prognostic unfavorable (1.38e-4)" "unprognostic (1.74e-1)" GZMA "CTLA3, HFSP" ENSG00000145649 "Granzyme A" P12544 5 55102646-55110252 "Enzymes, Predicted secreted proteins" Cytolysis "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 63.9" "Group enriched" "Detected in some" 42 "NK-cells: 1124.5;T-cells: 478.1" "Cell type enriched" "Detected in some" 254 "leukocyte: 268.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in all" 15 "gdT-cell: 943.6;MAIT T-cell: 927.9;memory CD4 T-cell: 250.8;memory CD8 T-cell: 922.8;naive CD8 T-cell: 495.6;NK-cell: 720.7" "Group enriched" "Detected in all" 42 "NK-cells: 720.7;T-cells: 943.6" "Cancer enriched" "Detected in some" 5 "lymphoma: 68.8" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Minor Salivary Gland - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Spleen - T-cells, Stomach - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA054134, HPA076751" Enhanced "Secreted to blood" Enzyme NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 8: Immune cells - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 4 "HPA054134: , HPA076751: " "unprognostic (2.27e-2)" "potential prognostic favorable (4.48e-4)" "unprognostic (3.53e-2)" "unprognostic (9.12e-2)" "unprognostic (1.61e-1)" "unprognostic (3.38e-1)" "potential prognostic unfavorable (1.15e-4)" "unprognostic (2.59e-1)" "unprognostic (6.08e-3)" "unprognostic (7.07e-2)" "unprognostic (1.16e-1)" "unprognostic (1.40e-1)" "unprognostic (6.98e-3)" "unprognostic (7.67e-3)" "unprognostic (8.44e-3)" "unprognostic (1.45e-2)" "unprognostic (4.71e-2)" "unprognostic (2.05e-1)" "unprognostic (8.77e-2)" "unprognostic (1.05e-1)" "unprognostic (1.05e-1)" "unprognostic (2.09e-1)" "unprognostic (2.31e-1)" "unprognostic (3.28e-1)" "unprognostic (1.32e-2)" "unprognostic (1.26e-1)" "unprognostic (3.17e-2)" "unprognostic (1.14e-1)" "unprognostic (2.35e-1)" "unprognostic (9.06e-3)" "unprognostic (1.57e-1)" GZMB "CCPI, CGL-1, CGL1, CSP-B, CSPB, CTLA1, CTSGL1, HLP, SECT" ENSG00000100453 "Granzyme B" P10144 14 24630954-24634267 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Cytolysis" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 62.9;lung: 15.7;lymphoid tissue: 33.8;urinary bladder: 17.2" "Group enriched" "Detected in some" 7 "NK-cells: 795.0;pDCs: 1958.5" "Cell type enriched" "Detected in single" 234 "leukocyte: 86.6" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in some" 9 "hypothalamus: 14.2" "Immune cell enriched" "Detected in all" 5 "plasmacytoid DC: 6750.5" "Lineage enriched" "Detected in all" 5 "dendritic cells: 6750.5" "Cancer enriched" "Detected in some" 59 "lymphoma: 294.4" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Prostate - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "CAB000376, HPA003418" Enhanced Approved Calyx "Secreted to blood" Enzyme NA NA 2170 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 3 Calyx "CAB000376: , HPA003418: " "unprognostic (6.28e-2)" "unprognostic (1.63e-3)" "unprognostic (2.23e-1)" "unprognostic (8.79e-3)" "unprognostic (1.31e-1)" "unprognostic (1.84e-2)" "potential prognostic unfavorable (3.41e-4)" "unprognostic (2.53e-1)" "unprognostic (1.94e-3)" "unprognostic (3.41e-2)" "unprognostic (7.55e-2)" "unprognostic (2.82e-1)" "unprognostic (2.71e-3)" "unprognostic (8.86e-2)" "unprognostic (4.26e-2)" "unprognostic (1.41e-1)" "unprognostic (2.31e-1)" "unprognostic (1.00e-1)" "unprognostic (8.40e-2)" "unprognostic (5.79e-3)" "potential prognostic favorable (5.66e-4)" "unprognostic (5.01e-2)" "unprognostic (1.59e-1)" "unprognostic (2.70e-1)" "unprognostic (1.98e-1)" "unprognostic (2.39e-1)" "unprognostic (1.33e-2)" "unprognostic (2.01e-1)" "unprognostic (4.12e-1)" "unprognostic (3.94e-1)" "unprognostic (2.10e-1)" GZMH "CCP-X, CGL-2, CSP-C, CTLA1, CTSGL2" ENSG00000100450 "Granzyme H" P20718 14 24606480-24609699 "Enzymes, Predicted secreted proteins" Cytolysis "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 31.9;lymphoid tissue: 23.6" "Group enriched" "Detected in some" 15 "NK-cells: 163.2;T-cells: 148.9" "Cell type enriched" "Detected in single" 195 "leukocyte: 133.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in all" 5 "gdT-cell: 1682.7;memory CD4 T-cell: 492.5;memory CD8 T-cell: 1389.7;naive CD8 T-cell: 1217.5" "Lineage enriched" "Detected in all" 7 "T-cells: 1682.7" "Cancer enriched" "Detected in single" 5 "lymphoma: 1.4" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Minor Salivary Gland - T-cells, Prostate - T-cells, Spleen - T-cells, Stomach - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA029200 Enhanced "Secreted to blood" Enzyme NA NA "Cluster 1: T-cells - Unknown function" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 8: Immune cells - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 53 "HPA029200: " "unprognostic (1.93e-2)" "unprognostic (6.66e-3)" "unprognostic (1.67e-1)" "unprognostic (2.52e-2)" "unprognostic (2.54e-1)" "unprognostic (8.75e-2)" "unprognostic (2.79e-2)" "unprognostic (1.64e-1)" "potential prognostic favorable (6.07e-4)" "unprognostic (2.41e-1)" "unprognostic (8.82e-2)" "unprognostic (1.41e-1)" "unprognostic (2.46e-2)" "unprognostic (8.04e-3)" "unprognostic (6.47e-3)" "unprognostic (1.34e-2)" "unprognostic (7.40e-2)" "unprognostic (1.24e-1)" "unprognostic (8.14e-2)" "unprognostic (4.91e-2)" "unprognostic (3.78e-2)" "unprognostic (1.22e-2)" "unprognostic (1.98e-2)" "unprognostic (1.99e-1)" "unprognostic (4.82e-2)" "unprognostic (9.17e-2)" "unprognostic (6.26e-3)" "unprognostic (1.74e-1)" "unprognostic (3.01e-1)" "unprognostic (6.77e-2)" "unprognostic (1.53e-1)" GZMK "PRSS, TRYP2" ENSG00000113088 "Granzyme K" P49863 5 55024256-55034570 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "lymphoid tissue: 93.3" "Group enriched" "Detected in some" 14 "NK-cells: 162.0;T-cells: 298.1" "Cell type enriched" "Detected in single" 275 "leukocyte: 167.1" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 24.8" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 742.7;NK-cell: 506.4" "Group enriched" "Detected in many" 199 "NK-cells: 506.4;T-cells: 742.7" "Not detected" "Not detected" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Colon - T-cells, Liver - T-cells, Lung - T-cells, Minor Salivary Gland - T-cells, Prostate - T-cells, Spleen - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA059953, HPA063181, HPA065895" Enhanced Approved "Golgi apparatus" "Secreted to blood" Enzyme NA NA "Cluster 1: T-cells - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 6: Leukemia - Signal transduction" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 3 "Golgi apparatus" "HPA059953: , HPA063181: , HPA065895: " "unprognostic (2.57e-1)" "potential prognostic favorable (9.32e-4)" "unprognostic (1.47e-1)" "potential prognostic favorable (3.64e-4)" "unprognostic (8.46e-2)" "unprognostic (4.37e-2)" "unprognostic (9.39e-3)" "unprognostic (1.65e-1)" "unprognostic (2.32e-3)" "unprognostic (1.55e-1)" "unprognostic (9.20e-2)" "unprognostic (1.35e-1)" "unprognostic (1.75e-2)" "potential prognostic favorable (6.25e-4)" "unprognostic (1.25e-2)" "unprognostic (8.75e-3)" "unprognostic (3.27e-2)" "unprognostic (2.42e-1)" "unprognostic (3.56e-1)" "unprognostic (2.79e-2)" "unprognostic (2.98e-1)" "unprognostic (6.90e-2)" "unprognostic (3.54e-2)" "unprognostic (2.40e-1)" "unprognostic (4.18e-2)" "unprognostic (3.01e-1)" "unprognostic (6.31e-2)" "unprognostic (1.57e-1)" "unprognostic (1.85e-1)" "unprognostic (2.57e-2)" "unprognostic (2.98e-1)" GZMM "LMET1, MET1" ENSG00000197540 "Granzyme M" P51124 19 544034-549924 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Cytolysis, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.4;lymphoid tissue: 21.9" "Group enriched" "Detected in some" 34 "NK-cells: 209.9;T-cells: 137.0" "Cell type enriched" "Detected in some" 85 "leukocyte: 92.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "gdT-cell: 585.3" "Group enriched" "Detected in all" 33 "NK-cells: 195.3;T-cells: 585.3" "Cancer enhanced" "Detected in some" "Leukemia: 5.5" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Minor Salivary Gland - T-cells, Pancreas - T-cells, Prostate - T-cells, Spleen - T-cells, Stomach - T-cells, Thyroid gland - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA015624 Enhanced "Secreted to blood" Immunity NA NA "Cluster 1: T-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 15: Non-specific - Transcription" "Cluster 59: Leukemia - T-cell receptor" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 1 "HPA015624: " "unprognostic (1.34e-2)" "unprognostic (5.56e-3)" "unprognostic (5.18e-2)" "unprognostic (1.03e-1)" "unprognostic (1.18e-1)" "unprognostic (2.84e-2)" "unprognostic (4.94e-2)" "potential prognostic favorable (5.19e-8)" "unprognostic (5.04e-1)" "unprognostic (2.12e-1)" "unprognostic (2.71e-1)" "unprognostic (3.10e-2)" "unprognostic (1.27e-1)" "unprognostic (6.76e-3)" "unprognostic (2.93e-3)" "unprognostic (7.28e-2)" "unprognostic (2.59e-1)" "unprognostic (1.59e-2)" "unprognostic (5.59e-2)" "unprognostic (5.72e-2)" "unprognostic (8.84e-2)" "unprognostic (2.12e-1)" "unprognostic (1.74e-1)" "unprognostic (3.98e-2)" "potential prognostic favorable (6.16e-4)" "unprognostic (1.54e-1)" H1-0 "H1.0, H1F0, H1FV" ENSG00000189060 "H1.0 linker histone" P07305 22 37805229-37807432 "Plasma proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 667.8" "Cell type enriched" "Detected in many" 7 "Esophageal apical cells: 2145.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "dendritic cells: 8.6;granulocytes: 18.3;monocytes: 12.5" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000843 Supported Supported "Nucleoplasm,Nuclear bodies,Golgi apparatus,Actin filaments" Yes No 310000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 15: Bone marrow - Innate immune response" "Cluster 16: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 84: Apical squamous epithelium - Cornification" 53 "Nucleoplasm, Nuclear bodies" "Golgi apparatus, Actin filaments" "HPA000843: " "potential prognostic favorable (6.40e-4)" "unprognostic (1.94e-1)" "unprognostic (4.06e-2)" "unprognostic (2.66e-2)" "unprognostic (2.19e-1)" "potential prognostic favorable (3.52e-4)" "unprognostic (1.67e-2)" "unprognostic (9.87e-2)" "unprognostic (1.22e-2)" "unprognostic (5.47e-3)" "unprognostic (7.58e-3)" "potential prognostic favorable (1.33e-4)" "unprognostic (2.72e-1)" "unprognostic (1.60e-2)" "potential prognostic unfavorable (1.32e-4)" "unprognostic (1.18e-1)" "unprognostic (1.36e-2)" "unprognostic (7.73e-3)" "unprognostic (1.15e-1)" "unprognostic (4.90e-3)" "unprognostic (1.84e-2)" "unprognostic (1.78e-2)" "unprognostic (1.38e-1)" "unprognostic (8.05e-2)" "unprognostic (3.80e-2)" "unprognostic (3.03e-1)" "unprognostic (3.27e-1)" "potential prognostic unfavorable (2.49e-4)" "unprognostic (6.58e-2)" H1-1 "H1.1, H1a, H1F1, HIST1H1A" ENSG00000124610 "H1.1 linker histone, cluster member" Q02539 6 26017032-26017787 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 29.3;Differentiating spermatogonia: 95.8;Early primary spermatocytes: 94.1;Esophageal basal cells: 29.5;Hepatic stellate cells: 12.9;Oocytes: 13.8;Undifferentiated spermatogonia: 20.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "T-reg: 1.7" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043753, HPA056830" Enhanced Supported Nucleoplasm NA Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 53: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 199 Nucleoplasm "HPA043753: , HPA056830: " "unprognostic (4.26e-2)" "unprognostic (8.42e-3)" "unprognostic (5.48e-2)" "unprognostic (7.25e-2)" H1-10 "H1FX, H1X, MGC15959, MGC8350" ENSG00000184897 "H1.10 linker histone" Q92522 3 129314771-129316286 "Plasma proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 948.8" "Cell type enhanced" "Detected in many" "Epididymal basal cells: 770.1;Plasma cells: 702.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012235, HPA040099, HPA068431" Enhanced Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes NA "Cluster 29: Non-specific - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 31: Non-specific - Transcription" "Cluster 20: Myeloma - Immune response" "Cluster 78: Plasma cells - Antibody production & ER-stress response" 71 "Nucleoplasm, Nucleoli" "Nucleoli rim, Mitotic chromosome" "CAB012235: , HPA040099: , HPA068431: " "unprognostic (5.26e-3)" "unprognostic (4.54e-2)" "unprognostic (2.03e-1)" "unprognostic (5.22e-2)" "unprognostic (1.77e-1)" "unprognostic (2.27e-1)" "unprognostic (1.34e-2)" "unprognostic (1.48e-1)" "unprognostic (6.11e-3)" "unprognostic (3.06e-1)" "unprognostic (3.16e-1)" "unprognostic (1.83e-1)" "unprognostic (5.17e-2)" "unprognostic (2.80e-2)" "unprognostic (3.35e-2)" "unprognostic (2.03e-1)" "unprognostic (5.59e-2)" "unprognostic (1.05e-1)" "unprognostic (1.70e-2)" "unprognostic (1.32e-2)" "unprognostic (1.93e-2)" "unprognostic (4.13e-3)" "unprognostic (1.90e-2)" "unprognostic (1.49e-2)" "unprognostic (1.81e-1)" "unprognostic (1.03e-1)" "unprognostic (1.26e-1)" "unprognostic (1.30e-1)" "unprognostic (5.14e-2)" H1-2 "H1.2, H1c, H1F2, H1s-1, HIST1H1C" ENSG00000187837 "H1.2 linker histone, cluster member" P16403 6 26055740-26056470 "Essential proteins, Plasma proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 742.5;Esophageal apical cells: 765.6;Monocyte progenitors: 486.6;Pancreatic acinar cells: 1284.5;Plasma cells: 486.5;Platelets: 2148.3" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 15.2;endothelial cell: 13.0;vascular associated smooth muscle cell: 13.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 259.2;eosinophil: 460.0;neutrophil: 230.5" "Lineage enriched" "Detected in all" 6 "granulocytes: 460.0" "Cancer enhanced" "Detected in all" "Myeloma: 366.4" "Heart muscle - Cardiomyocytes, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "CAB011507, HPA055907" Supported Supported "Nucleoplasm,Nucleoli rim" NA NA 16000000 "Cluster 22: Eosinophils - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 47: Platelets - Hemostasis" 112 "Nucleoplasm, Nucleoli rim" "CAB011507: , HPA055907: " "unprognostic (6.63e-2)" "unprognostic (2.00e-1)" "potential prognostic favorable (9.10e-4)" "unprognostic (1.50e-1)" "unprognostic (1.18e-1)" "unprognostic (3.88e-1)" "unprognostic (3.79e-1)" "unprognostic (7.74e-2)" "unprognostic (6.15e-2)" "unprognostic (1.16e-2)" "unprognostic (1.48e-1)" "unprognostic (2.14e-2)" "unprognostic (2.43e-1)" "unprognostic (2.31e-2)" "unprognostic (1.37e-2)" "unprognostic (1.14e-1)" "unprognostic (4.85e-2)" "unprognostic (4.98e-2)" "unprognostic (3.47e-1)" "unprognostic (1.93e-3)" "unprognostic (1.54e-1)" "unprognostic (2.37e-1)" "unprognostic (2.05e-3)" "unprognostic (6.66e-2)" "unprognostic (1.81e-1)" "unprognostic (6.76e-2)" "unprognostic (9.72e-2)" "unprognostic (1.06e-1)" "unprognostic (7.98e-2)" H1-3 "H1.3, H1d, H1F3, H1s-2, HIST1H1D" ENSG00000124575 "H1.3 linker histone, cluster member" P16402 6 26234212-26234987 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.9;choroid plexus: 7.1" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 768.3;Hematopoietic stem cells: 185.4;Innate lymphoid cells: 122.8;Megakaryocyte progenitors: 275.6;Megakaryocyte-Erythroid progenitors: 107.8;Monocyte progenitors: 380.9;Neutrophil progenitors: 130.1;NK-cells: 144.8;Plasma cells: 227.5;T-cells: 118.3;Thymocytes: 199.9" "Group enriched" "Detected in some" 4 "central nervous system macrophage: 12.7;leukocyte: 24.8" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 10.0;Colon Adenocarcinoma (TCGA): 10.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Adipose visceral - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA055907 Supported NA NA 12000000 "Cluster 24: Non-specific - Transcription" "Cluster 15: Bone marrow - Innate immune response" "Cluster 2: Neurons - Nucleosome" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 37 "HPA055907: " "unprognostic (3.00e-2)" "unprognostic (1.32e-1)" "potential prognostic favorable (2.88e-4)" "unprognostic (5.51e-2)" "unprognostic (1.07e-1)" "unprognostic (5.44e-3)" "unprognostic (2.99e-2)" "unprognostic (9.35e-2)" "unprognostic (1.80e-1)" "unprognostic (1.51e-1)" "unprognostic (1.25e-1)" "unprognostic (2.99e-3)" "unprognostic (8.26e-2)" "unprognostic (2.24e-1)" "unprognostic (7.01e-2)" H1-4 "H1.4, H1e, H1F4, H1s-4, HIST1H1E" ENSG00000168298 "H1.4 linker histone, cluster member" P10412 6 26156329-26157115 "Disease related genes, Predicted intracellular proteins" DNA-binding "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "bone marrow: 49.4" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 336.2;Megakaryocyte progenitors: 202.6;Megakaryocyte-Erythroid progenitors: 110.0;Megakaryocytes: 105.1;Monocyte progenitors: 251.1;Neutrophil progenitors: 131.3;NK-cells: 112.1;Plasma cells: 160.2" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 19.3;leukocyte: 22.4" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 27.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB011506, HPA055907" Supported Supported "Nuclear speckles,Cytosol" NA Yes 24000000 "Cluster 32: Basophils - Transcription" "Cluster 15: Bone marrow - Innate immune response" "Cluster 2: Neurons - Nucleosome" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 251 "Nuclear speckles" Cytosol "CAB011506: , HPA055907: " "unprognostic (9.01e-2)" "unprognostic (6.60e-2)" "unprognostic (8.52e-2)" "unprognostic (6.25e-2)" "unprognostic (3.51e-2)" "unprognostic (2.92e-1)" "unprognostic (2.43e-1)" "unprognostic (9.01e-3)" "potential prognostic unfavorable (1.40e-7)" "unprognostic (1.33e-2)" "potential prognostic unfavorable (6.44e-4)" "unprognostic (2.83e-2)" "unprognostic (2.70e-2)" "unprognostic (1.36e-1)" "unprognostic (5.33e-2)" "unprognostic (3.94e-1)" "unprognostic (1.11e-1)" "unprognostic (3.36e-2)" "unprognostic (1.31e-2)" "unprognostic (1.58e-1)" "unprognostic (1.80e-1)" H1-5 "H1b, H1F5, H1s-3, HIST1H1B" ENSG00000184357 "H1.5 linker histone, cluster member" P16401 6 27866792-27867588 "Plasma proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 7.3;lymphoid tissue: 1.9" "Group enriched" "Detected in many" 4 "Erythrocyte progenitors: 703.2;Megakaryocyte progenitors: 312.7;Monocyte progenitors: 315.7" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Bladder Urothelial Carcinoma (TCGA): 12.8;Colon Adenocarcinoma (TCGA): 22.7;Lung Adenocarcinoma (TCGA): 6.3;Uterine Corpus Endometrial Carcinoma (TCGA): 10.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 10.3;dendritic cells: 12.2;T-cells: 3.3" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "CAB012241, HPA055907, HPA060331" Supported Supported Nucleoplasm NA NA 9600000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 25: Non-specific - Transcription" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 74 Nucleoplasm "CAB012241: , HPA055907: , HPA060331: " "potential prognostic unfavorable (6.41e-4)" "unprognostic (6.88e-2)" "potential prognostic favorable (9.40e-6)" "unprognostic (1.86e-1)" "unprognostic (9.82e-2)" "unprognostic (2.57e-1)" "unprognostic (1.19e-1)" "unprognostic (9.65e-2)" "unprognostic (1.75e-1)" "unprognostic (2.05e-1)" "unprognostic (4.39e-1)" "unprognostic (4.50e-3)" "unprognostic (2.36e-1)" "unprognostic (5.81e-2)" H1-6 "H1FT, H1t, HIST1H1T" ENSG00000187475 "H1.6 linker histone, cluster member" P22492 6 26107412-26108135 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 8 "testis: 1.0" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 4.6;Early primary spermatocytes: 7.2;Late primary spermatocytes: 1.7;Platelets: 1.4;Undifferentiated spermatogonia: 3.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 13 "neutrophil: 1.3" "Lineage enriched" "Detected in single" 13 "granulocytes: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "olfactory bulb: 3.3" "HPA065718, HPA068266" Enhanced NA NA "Cluster 47: Testis - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 47: Leukemia - Hemostasis" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 28 "HPA065718: , HPA068266: " "unprognostic (6.20e-2)" H1-7 "H1FNT, H1T2, HANP1" ENSG00000187166 "H1.7 linker histone" Q75WM6 12 48328980-48330279 "Predicted intracellular proteins" "Differentiation, DNA condensation, Spermatogenesis" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 262 "testis: 207.9" "Group enriched" "Detected in some" 7 "Early spermatids: 2080.0;Late spermatids: 7369.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA046204 Approved Approved "Perinuclear theca,Connecting piece,Mid piece,Principal piece,End piece" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 85 "Perinuclear theca, Connecting piece, Mid piece, Principal piece, End piece" "HPA046204: " H1-8 H1FOO ENSG00000178804 "H1.8 linker histone" Q8IZA3 3 129543175-129551467 "Predicted intracellular proteins" Meiosis DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 30 "testis: 7.0" "Group enriched" "Detected in some" 6 "Late primary spermatocytes: 119.4;Oocytes: 216.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA037992 Enhanced NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 11: White matter - Signal transduction" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" 3 "HPA037992: " H2AB1 "H2A.B.2, H2AFB1" ENSG00000274183 "H2A.B variant histone 1" P0C5Y9 X 154884972-154885558 "Predicted intracellular proteins" "mRNA processing" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 17 "testis: 10.6" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 10.6;Early spermatids: 19.8;Late primary spermatocytes: 18.4;Late spermatids: 65.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Ovary Serous Cystadenocarcinoma (TCGA): 1.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lymphoma: 4.8" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 50: Lymphoma - Unknown function" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 9 "unprognostic (3.59e-1)" H2AB2 "H2A.B.1, H2AFB2" ENSG00000277858 "H2A.B variant histone 2" P0C5Z0 X 155380709-155381299 "Predicted intracellular proteins" "mRNA processing" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 9 "testis: 7.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "breast cancer: 2.0;lymphoma: 5.3" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 50: Lymphoma - Unknown function" 2 "unprognostic (2.81e-2)" H2AB3 "H2A.B.1, H2AFB, H2AFB3" ENSG00000277745 "H2A.B variant histone 3" P0C5Z0 X 155459415-155460005 "Predicted intracellular proteins" "mRNA processing" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 26 "testis: 24.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "breast cancer: 2.0;lymphoma: 5.3" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 50: Lymphoma - Unknown function" 2 "unprognostic (2.81e-2)" H2AC1 "bA317E16.2, H2AFR, HIST1H2AA" ENSG00000164508 "H2A clustered histone 1" Q96QV6 6 25723397-25726562 "Plasma proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 17 "testis: 5.4" "Group enriched" "Detected in some" 6 "Differentiating spermatogonia: 172.6;Early primary spermatocytes: 681.1;Late primary spermatocytes: 303.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA041189 Supported Supported Nucleoplasm NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 4 Nucleoplasm "HPA041189: " H2AC11 "H2A.1b, H2A/p, H2AFP, HIST1H2AG, pH2A/f" ENSG00000196787 "H2A clustered histone 11" P0C0S8 6 27133043-27133535 "Essential proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 12.2;testis: 5.5" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 271.8;Erythrocytes: 56.8;Hematopoietic stem cells: 33.5;Megakaryocyte progenitors: 123.1;Megakaryocyte-Erythroid progenitors: 41.7;Monocyte progenitors: 99.7;Neutrophil progenitors: 29.4;Plasma cells: 41.1;Platelets: 71.9" "Group enriched" "Detected in some" 7 "central nervous system macrophage: 4.1;leukocyte: 2.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA041189 Supported Supported Nucleoplasm NA Yes "Cluster 43: Non-specific - Transcription & Translation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 60 Nucleoplasm "HPA041189: " "unprognostic (1.79e-1)" "unprognostic (8.81e-3)" "unprognostic (1.51e-1)" "unprognostic (5.69e-2)" "unprognostic (2.01e-1)" "unprognostic (1.97e-2)" "unprognostic (1.45e-1)" "unprognostic (1.60e-2)" "unprognostic (5.15e-3)" "unprognostic (1.82e-1)" "unprognostic (6.09e-2)" "unprognostic (9.75e-2)" "unprognostic (1.90e-1)" "unprognostic (2.01e-1)" "unprognostic (1.22e-2)" "unprognostic (1.65e-2)" "unprognostic (2.50e-1)" "unprognostic (9.06e-2)" "unprognostic (1.57e-1)" "unprognostic (1.62e-2)" "unprognostic (1.79e-1)" "unprognostic (2.40e-2)" "unprognostic (1.77e-1)" "unprognostic (8.67e-2)" "unprognostic (8.62e-2)" "unprognostic (2.72e-2)" "unprognostic (1.14e-1)" H2AC12 "dJ86C11.1, H2A/S, H2AFALii, HIST1H2AH" ENSG00000274997 "H2A clustered histone 12" Q96KK5 6 27147106-27147562 "Essential proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "bone marrow: 8.3" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 215.1;Erythrocytes: 22.7;Megakaryocyte progenitors: 85.2;Monocyte progenitors: 81.1;Neutrophil progenitors: 26.7;Plasma cells: 33.6;Tuft cells: 46.1" "Cell type enriched" "Detected in single" 4 "central nervous system macrophage: 1.6" "Cancer enhanced" "Detected in some" "Colon Adenocarcinoma (TCGA): 14.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 11.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004030, HPA041189" Supported Supported Nucleoplasm NA Yes "Cluster 34: B-cells - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 30: White matter - Myelination" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 6 Nucleoplasm "CAB004030: , HPA041189: " "unprognostic (5.22e-2)" "unprognostic (5.25e-2)" "unprognostic (1.78e-1)" "unprognostic (3.38e-1)" "unprognostic (2.04e-1)" "unprognostic (1.21e-2)" "unprognostic (1.33e-2)" "unprognostic (5.46e-2)" H2AC13 "H2A/c, H2AFC, HIST1H2AI" ENSG00000196747 "H2A clustered histone 13" P0C0S8 6 27808173-27808667 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.9" "Cell type enhanced" "Detected in some" "Erythrocyte progenitors: 106.7;Erythrocytes: 17.7;Megakaryocyte progenitors: 49.9;Monocyte progenitors: 41.3;Neutrophil progenitors: 8.6;Plasma cells: 12.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" HPA041189 Supported Supported Nucleoplasm NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 54 Nucleoplasm "HPA041189: " "unprognostic (1.53e-3)" "unprognostic (6.10e-2)" "unprognostic (5.43e-3)" "unprognostic (2.22e-1)" "unprognostic (2.96e-1)" "unprognostic (4.04e-1)" "unprognostic (1.46e-1)" "unprognostic (1.05e-1)" "unprognostic (1.17e-1)" "unprognostic (3.48e-2)" "unprognostic (2.71e-2)" "unprognostic (1.38e-3)" "unprognostic (2.68e-2)" "unprognostic (8.36e-3)" "potential prognostic favorable (6.51e-4)" "unprognostic (1.72e-1)" "unprognostic (1.01e-1)" "unprognostic (2.66e-3)" "unprognostic (2.61e-1)" "unprognostic (3.13e-2)" "unprognostic (3.55e-1)" "unprognostic (5.42e-3)" "unprognostic (5.87e-2)" "unprognostic (2.53e-1)" "unprognostic (3.66e-1)" "unprognostic (1.04e-1)" H2AC14 "H2A/E, H2AFE, HIST1H2AJ" ENSG00000276368 "H2A clustered histone 14" Q99878 6 27814302-27814777 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "bone marrow: 6.9" "Cell type enhanced" "Detected in some" "Erythrocyte progenitors: 537.4;Erythrocytes: 118.6;Megakaryocyte progenitors: 227.1;Monocyte progenitors: 193.4;Plasma cells: 55.8" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 11.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 2.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" HPA041189 Supported Supported Nucleoplasm NA Yes "Cluster 18: Non-specific - Translation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 19 Nucleoplasm "HPA041189: " "unprognostic (4.79e-3)" "unprognostic (1.84e-2)" "unprognostic (9.22e-3)" "unprognostic (2.78e-1)" "unprognostic (9.55e-2)" "unprognostic (3.94e-2)" "unprognostic (1.92e-1)" "unprognostic (7.08e-2)" "unprognostic (1.09e-2)" "unprognostic (7.42e-2)" "unprognostic (3.68e-1)" "unprognostic (2.48e-1)" H2AC15 "H2A/d, H2AFD, HIST1H2AK" ENSG00000275221 "H2A clustered histone 15" P0C0S8 6 27837880-27838375 "Essential proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 81.8;Erythrocytes: 11.8;Hematopoietic stem cells: 29.1;Megakaryocyte progenitors: 53.1;Megakaryocyte-Erythroid progenitors: 29.0;Monocyte progenitors: 33.9;NK-cells: 11.6;Plasma cells: 14.8;T-cells: 11.8" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 3.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Testis - Sertoli cells" "Low region specificity" "Detected in some" HPA041189 Supported Supported Nucleoplasm NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 35: Non-specific - Mixed function" "Cluster 55: Non-specific - Transcription" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 47 Nucleoplasm "HPA041189: " "unprognostic (4.71e-2)" "unprognostic (6.31e-2)" "unprognostic (1.59e-2)" "unprognostic (1.06e-1)" "unprognostic (1.49e-1)" "unprognostic (1.93e-2)" "unprognostic (8.71e-3)" "unprognostic (4.20e-3)" "unprognostic (9.56e-2)" H2AC16 "dJ193B12.9, H2A/i, H2AFI, HIST1H2AL" ENSG00000276903 "H2A clustered histone 16" P0C0S8 6 27865317-27865798 "Essential proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 10 "bone marrow: 7.1" "Cell type enhanced" "Detected in some" "Erythrocyte progenitors: 353.9;Erythrocytes: 78.8;Megakaryocyte progenitors: 148.2;Monocyte progenitors: 139.6;Neutrophil progenitors: 31.4;Plasma cells: 34.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 5.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" HPA041189 Supported Supported Nucleoplasm NA NA "Cluster 32: Basophils - Transcription" "Cluster 15: Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 47 Nucleoplasm "HPA041189: " "potential prognostic unfavorable (9.44e-4)" "unprognostic (2.28e-2)" "unprognostic (1.85e-3)" "unprognostic (7.73e-2)" "unprognostic (2.58e-1)" "unprognostic (3.29e-1)" "unprognostic (8.94e-3)" "unprognostic (1.73e-1)" "unprognostic (1.82e-1)" "unprognostic (1.21e-2)" "unprognostic (4.20e-1)" "unprognostic (1.60e-1)" H2AC17 "H2A.1, H2A/n, H2AFN, HIST1H2AM" ENSG00000278677 "H2A clustered histone 17" P0C0S8 6 27892699-27893185 "Essential proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 3.0" "Group enriched" "Detected in many" 4 "Erythrocyte progenitors: 252.7;Megakaryocyte progenitors: 140.4;Monocyte progenitors: 170.4" "Group enriched" "Detected in some" 14 "central nervous system macrophage: 3.3;leukocyte: 2.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 63.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041189 Supported Supported Nucleoplasm NA NA "Cluster 32: Basophils - Transcription" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 48 Nucleoplasm "HPA041189: " "unprognostic (1.23e-3)" "unprognostic (1.57e-1)" "unprognostic (1.43e-1)" "unprognostic (1.03e-1)" "unprognostic (1.14e-1)" "unprognostic (3.59e-2)" "unprognostic (6.42e-3)" "unprognostic (3.86e-1)" "unprognostic (1.17e-3)" "unprognostic (3.46e-2)" "unprognostic (1.44e-2)" "unprognostic (1.74e-2)" "unprognostic (3.73e-3)" "unprognostic (5.56e-2)" "unprognostic (1.16e-2)" "unprognostic (3.65e-3)" "unprognostic (5.57e-3)" "unprognostic (3.68e-1)" "unprognostic (2.41e-1)" "unprognostic (1.56e-1)" "unprognostic (1.94e-1)" "unprognostic (1.84e-1)" "unprognostic (3.35e-1)" "unprognostic (4.66e-2)" "unprognostic (4.91e-2)" H2AC18 "H2A.2, H2A/q, H2AFO, HIST2H2AA, HIST2H2AA3" ENSG00000288825 "H2A clustered histone 18" Q6FI13 1 149842218-149842750 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 82.0;prostate: 54.7" "Cell type enhanced" "Detected in single" "Platelets: 1.4" "Group enriched" "Detected in some" 19 "choroid plexus: 88.7;pons: 23.6" "Immune cell enriched" "Detected in many" 4 "basophil: 237.7" "Lineage enriched" "Detected in all" 7 "granulocytes: 237.7" "Group enriched" "Detected in many" 5 "lymphoma: 18.2;Myeloma: 30.4;thyroid cancer: 40.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041189 Approved Supported Nucleoplasm NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 36: Choroid plexus - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 47: Platelets - Hemostasis" 26 Nucleoplasm "HPA041189: " H2AC19 "H2A/r, HIST2H2AA4" ENSG00000288859 "H2A clustered histone 19" Q6FI13 1 149851061-149851594 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 113.5;choroid plexus: 190.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "neutrophil: 1926.5" "Lineage enriched" "Detected in all" 9 "granulocytes: 1926.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA041189 Supported Supported Nucleoplasm NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 55: Non-specific - Transcription" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 102: Non-specific - Mixed function" 3 Nucleoplasm "HPA041189: " H2AC20 "H2A, H2A/q, H2AFQ, HIST2H2AC" ENSG00000184260 "H2A clustered histone 20" Q16777 1 149886918-149887411 "Essential proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "bone marrow: 23.9" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 334.8;Megakaryocyte progenitors: 158.6;Monocyte progenitors: 209.0;Neutrophil progenitors: 94.3;Plasma cells: 95.0;Tuft cells: 92.2" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 6.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA041189 Supported Supported Nucleoplasm NA Yes "Cluster 35: Neutrophils - Protein binding" "Cluster 15: Bone marrow - Innate immune response" "Cluster 39: Astrocytes - Mixed function" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 88 Nucleoplasm "HPA041189: " "unprognostic (3.92e-2)" "unprognostic (6.44e-2)" "unprognostic (4.26e-2)" "unprognostic (1.46e-1)" "unprognostic (6.95e-2)" "unprognostic (3.91e-2)" "unprognostic (6.15e-2)" "unprognostic (2.46e-2)" "unprognostic (3.67e-2)" "potential prognostic unfavorable (9.11e-7)" "unprognostic (1.28e-2)" "unprognostic (2.15e-2)" "unprognostic (6.82e-2)" "unprognostic (4.16e-2)" "unprognostic (1.25e-1)" "unprognostic (3.86e-3)" "unprognostic (8.10e-2)" "unprognostic (7.10e-3)" "unprognostic (1.33e-2)" "unprognostic (4.77e-2)" "unprognostic (1.35e-1)" "unprognostic (1.31e-2)" "unprognostic (7.42e-3)" "unprognostic (8.01e-2)" "unprognostic (3.78e-1)" "unprognostic (7.60e-2)" "unprognostic (1.85e-2)" "unprognostic (5.92e-2)" H2AC21 HIST2H2AB ENSG00000184270 "H2A clustered histone 21" Q8IUE6 1 149887469-149887965 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 5 "bone marrow: 3.2" "Cell type enhanced" "Detected in some" "Erythrocyte progenitors: 46.6;Megakaryocyte progenitors: 33.6;Monocyte progenitors: 33.5;Mucous neck cells: 10.7;Neutrophil progenitors: 7.5;Plasma cells: 6.9;Tuft cells: 11.5" "Cell type enhanced" "Detected in single" "central nervous system macrophage: 1.4" "Cancer enhanced" "Detected in some" "Bladder Urothelial Carcinoma (TCGA): 4.2;Colon Adenocarcinoma (TCGA): 4.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB011483, HPA041189" Supported Supported Nucleoplasm NA NA 76000000 "Cluster 24: Non-specific - Transcription" "Cluster 15: Bone marrow - Innate immune response" "Cluster 31: Non-specific - Transcription" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 109 Nucleoplasm "CAB011483: , HPA041189: " "unprognostic (1.52e-1)" "unprognostic (5.39e-2)" "unprognostic (1.90e-2)" "unprognostic (3.28e-1)" "unprognostic (1.20e-1)" "unprognostic (1.38e-1)" "unprognostic (2.67e-1)" "unprognostic (3.27e-1)" "unprognostic (1.08e-2)" "unprognostic (3.56e-2)" H2AC25 "H2AW, HIST3H2A, MGC3165" ENSG00000181218 "H2A clustered histone 25" Q7L7L0 1 228434777-228457873 "Essential proteins, Plasma proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 75.7" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 13.1;Brain inhibitory neurons: 8.9;Choroid plexus epithelial cells: 4.1;Microglia: 10.9;Oligodendrocyte progenitor cells: 1.7;Oligodendrocytes: 4.1;Other brain neurons: 7.8;Papillary tip epithelial cells: 2.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041189 Supported Supported Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 64: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 1: Neuronal - Visual perception" "Cluster 98: Neurons - Neurotransmission & signaling" 13 Nucleoplasm "HPA041189: " "unprognostic (3.69e-2)" "unprognostic (4.44e-3)" "unprognostic (8.00e-2)" "unprognostic (1.63e-2)" "unprognostic (1.65e-3)" "validated prognostic favorable (2.15e-4)" "validated prognostic favorable (1.40e-4)" "potential prognostic unfavorable (5.49e-4)" "unprognostic (8.43e-2)" "unprognostic (1.39e-1)" "unprognostic (1.63e-2)" "potential prognostic unfavorable (1.39e-4)" "unprognostic (1.35e-2)" "unprognostic (2.65e-1)" "unprognostic (1.36e-3)" "unprognostic (4.43e-3)" "unprognostic (1.57e-2)" "unprognostic (1.14e-2)" "unprognostic (2.20e-1)" "unprognostic (7.06e-2)" "unprognostic (2.62e-2)" "unprognostic (1.87e-1)" "unprognostic (2.99e-1)" "unprognostic (3.28e-2)" "unprognostic (5.43e-3)" "unprognostic (2.41e-1)" "unprognostic (3.28e-1)" "unprognostic (1.45e-1)" "unprognostic (3.68e-1)" H2AC4 "H2A/m, H2AFM, HIST1H2AB" ENSG00000278463 "H2A clustered histone 4" P04908 6 26033092-26033618 "Essential proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "bone marrow: 1.4" "Cell type enhanced" "Detected in some" "Erythrocyte progenitors: 40.6;Erythrocytes: 7.6;Late spermatids: 5.8;Megakaryocyte progenitors: 20.0;Monocyte progenitors: 24.5;Neutrophil progenitors: 6.7;Plasma cells: 6.2;Tuft cells: 11.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Colon Adenocarcinoma (TCGA): 4.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA041189 Supported Supported Nucleoplasm NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 44: Non-specific - Mixed function" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 132 Nucleoplasm "HPA041189: " "unprognostic (9.56e-3)" "unprognostic (3.36e-1)" "unprognostic (2.76e-1)" "unprognostic (1.66e-1)" "unprognostic (3.45e-1)" "unprognostic (1.68e-1)" "unprognostic (9.02e-2)" H2AC6 "H2AFL, HIST1H2AC" ENSG00000180573 "H2A clustered histone 6" Q93077 6 26124145-26139116 "Cancer-related genes, Essential proteins, Predicted intracellular proteins" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in all" 7 "Platelets: 6283.4" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 392.5;leukocyte: 179.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1566.8" "Lineage enriched" "Detected in all" 14 "granulocytes: 1566.8" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" HPA041189 Supported Supported Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 55: Non-specific - Transcription" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 18 Nucleoplasm "HPA041189: " "unprognostic (3.13e-3)" "unprognostic (1.49e-1)" "unprognostic (5.94e-2)" "unprognostic (1.85e-2)" "unprognostic (3.42e-2)" "unprognostic (2.37e-1)" "unprognostic (2.92e-1)" "unprognostic (1.79e-1)" "potential prognostic unfavorable (5.27e-4)" "unprognostic (1.54e-3)" "unprognostic (1.14e-1)" "unprognostic (2.07e-1)" "unprognostic (2.69e-2)" "unprognostic (5.67e-2)" "unprognostic (1.49e-1)" "unprognostic (3.15e-1)" "unprognostic (1.80e-1)" "unprognostic (2.50e-1)" "unprognostic (2.20e-2)" "potential prognostic unfavorable (9.32e-4)" "unprognostic (2.11e-1)" "unprognostic (2.20e-1)" "unprognostic (4.29e-2)" "unprognostic (8.14e-2)" "unprognostic (1.19e-1)" "unprognostic (3.18e-2)" "unprognostic (1.15e-1)" "unprognostic (2.93e-1)" "unprognostic (5.86e-2)" H2AC7 "H2A.3, H2A/g, H2AFG, HIST1H2AD" ENSG00000196866 "H2A clustered histone 7" P20671 6 26198784-26199293 "Essential proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enriched" "Detected in single" 18 "Microglia: 4.5" "Cell type enriched" "Detected in some" 4 "central nervous system macrophage: 7.7" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 12.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 18.2" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Mitotic cells (Minor salivary gland)" "Low region specificity" "Detected in all" HPA041189 Supported Supported Nucleoplasm NA Yes "Cluster 20: Non-specific - DNA binding" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 12 Nucleoplasm "HPA041189: " "unprognostic (4.84e-1)" "unprognostic (1.53e-1)" "unprognostic (1.21e-1)" "unprognostic (2.37e-2)" "unprognostic (2.39e-1)" "unprognostic (4.77e-2)" "unprognostic (3.48e-1)" "unprognostic (1.32e-1)" "unprognostic (1.78e-1)" "unprognostic (1.88e-1)" "unprognostic (1.38e-1)" "unprognostic (1.20e-1)" "unprognostic (9.04e-2)" "unprognostic (1.04e-1)" "unprognostic (1.51e-1)" H2AC8 "H2A.1, H2A/a, H2AFA, HIST1H2AE" ENSG00000277075 "H2A clustered histone 8" P04908 6 26216921-26217437 "Essential proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 37.1;prostate: 32.7" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 136.5;Erythrocyte progenitors: 64.0;Esophageal apical cells: 64.4;Monocyte progenitors: 43.2;Platelets: 278.1" "Group enriched" "Detected in some" 5 "central nervous system macrophage: 9.6;choroid plexus epithelial cell: 2.9" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 68.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "CAB012242, HPA041189" Supported Supported Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 47: Platelets - Hemostasis" 33 Nucleoplasm "CAB012242: , HPA041189: " "unprognostic (6.74e-3)" "unprognostic (5.11e-2)" "unprognostic (1.47e-2)" "potential prognostic unfavorable (9.94e-4)" "unprognostic (6.45e-2)" "unprognostic (1.77e-1)" "unprognostic (2.32e-1)" "unprognostic (7.60e-2)" "unprognostic (6.61e-2)" "unprognostic (9.42e-2)" "unprognostic (2.66e-1)" "unprognostic (5.18e-2)" "unprognostic (6.61e-3)" "unprognostic (4.74e-2)" "unprognostic (9.11e-3)" "unprognostic (4.24e-3)" "unprognostic (2.25e-1)" "potential prognostic favorable (5.18e-4)" "unprognostic (8.58e-3)" "unprognostic (2.76e-1)" "unprognostic (3.00e-2)" "unprognostic (2.71e-1)" "unprognostic (1.95e-1)" "unprognostic (2.28e-1)" "unprognostic (2.14e-1)" "unprognostic (2.31e-1)" H2AJ "FLJ10903, H2AFJ, MGC921" ENSG00000246705 "H2A.J histone" Q9BTM1 12 14774405-14778002 "Essential proteins, Plasma proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 541.3" "Cell type enhanced" "Detected in many" "Early spermatids: 2734.8;Esophageal apical cells: 3319.8;Late primary spermatocytes: 4295.4;Late spermatids: 6091.5;Platelets: 1246.8" "Cell type enhanced" "Detected in many" "vascular associated smooth muscle cell: 45.1" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 1356.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041189 Supported Approved Nucleoplasm NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 57: Testis - Spermatogenesis" "Cluster 30: White matter - Myelination" "Cluster 27: Breast cancer - Unknown function" "Cluster 84: Apical squamous epithelium - Cornification" 8 Nucleoplasm "HPA041189: " "unprognostic (1.66e-1)" "unprognostic (2.68e-1)" "unprognostic (7.16e-2)" "unprognostic (1.72e-1)" "unprognostic (1.12e-3)" "potential prognostic unfavorable (1.43e-5)" "unprognostic (2.71e-3)" "unprognostic (9.32e-3)" "unprognostic (1.35e-2)" "unprognostic (7.91e-3)" "unprognostic (3.83e-3)" "unprognostic (1.05e-2)" "unprognostic (2.81e-3)" "unprognostic (3.46e-2)" "unprognostic (2.38e-2)" "unprognostic (2.22e-1)" "unprognostic (9.02e-3)" "unprognostic (1.52e-1)" "unprognostic (8.21e-2)" "unprognostic (5.30e-2)" "unprognostic (7.19e-2)" "unprognostic (1.32e-2)" "unprognostic (6.39e-2)" "unprognostic (3.07e-2)" "unprognostic (1.84e-1)" "unprognostic (1.83e-1)" "unprognostic (2.04e-2)" "unprognostic (3.01e-2)" "unprognostic (4.25e-1)" H2AL1Q "H2A.L.1, H2AL1QP" ENSG00000249467 "H2A.L variant histone 1Q" X 36719829-36720573 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 26 "testis: 7.4" "Cell type enriched" "Detected in some" 5 "Late spermatids: 692.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 46: Brainstem - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" H2AL3 "H2A.L.3, H2AL1RP" ENSG00000229674 "H2A.L variant histone 3" A0A3B3IU63 X 37994272-37994904 "Predicted intracellular proteins" DNA-binding "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Tissue enriched" "Detected in single" 11 "testis: 4.2" "Cell type enriched" "Detected in some" 5 "Late spermatids: 115.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 33: Neurons - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" H2AP "CXorf27, HIP17, HYPM" ENSG00000187516 "H2A.P histone" O75409 X 37990779-37991314 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 197 "testis: 44.9" "Cell type enriched" "Detected in some" 5 "Late spermatids: 2063.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "testis cancer: 1.1" "Testis - Late spermatids" "Not detected" "Not detected" HPA003356 Enhanced NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 33: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 23 "HPA003356: " H2AX H2AFX ENSG00000188486 "H2A.X variant histone" P16104 11 119093874-119095465 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA recombination, DNA repair, Host-virus interaction, Meiosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 199.9;Breast myoepithelial cells: 153.3;Breast secretory cells: 139.8;Epididymal basal cells: 156.9;pDCs: 145.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012264, HPA041189, HPA051647" Supported Supported "Nucleoplasm,Nuclear speckles" Yes Yes "Cluster 42: Non-specific - Vesicular transport" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 20: Non-specific - Transcription regulation" 219 Nucleoplasm "Nuclear speckles" "CAB012264: , HPA041189: , HPA051647: " "unprognostic (1.42e-1)" "unprognostic (1.19e-1)" "unprognostic (1.45e-1)" "unprognostic (1.22e-1)" "unprognostic (2.61e-1)" "unprognostic (2.51e-1)" "unprognostic (1.44e-1)" "unprognostic (2.80e-1)" "unprognostic (1.20e-1)" "potential prognostic unfavorable (6.00e-9)" "unprognostic (4.59e-3)" "unprognostic (2.37e-3)" "potential prognostic unfavorable (1.58e-4)" "potential prognostic unfavorable (9.42e-6)" "unprognostic (1.72e-3)" "unprognostic (3.56e-2)" "unprognostic (1.04e-1)" "unprognostic (2.57e-2)" "unprognostic (2.82e-2)" "unprognostic (8.43e-2)" "unprognostic (7.28e-2)" "unprognostic (2.71e-2)" "unprognostic (2.54e-1)" "unprognostic (2.80e-1)" "unprognostic (4.04e-2)" "unprognostic (2.52e-2)" "unprognostic (1.56e-1)" "unprognostic (3.62e-1)" "unprognostic (5.82e-3)" H2AZ1 "H2A.Z, H2AFZ, H2AZ" ENSG00000164032 "H2A.Z variant histone 1" P0C0S5 4 99948086-99950355 "Essential proteins, Plasma proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 1384.9;Esophageal basal cells: 1905.9;Extravillous trophoblasts: 1621.5;Migrating cytotrophoblasts: 1125.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "CAB022549, HPA057236" Supported Supported Nucleoplasm NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 31: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Non-specific - Cell proliferation" 143 Nucleoplasm "CAB022549: , HPA057236: " "unprognostic (1.80e-2)" "unprognostic (1.50e-2)" "unprognostic (3.51e-3)" "unprognostic (2.19e-2)" "unprognostic (1.24e-1)" "unprognostic (1.16e-1)" "unprognostic (1.25e-1)" "unprognostic (1.35e-3)" "potential prognostic unfavorable (1.98e-4)" "potential prognostic favorable (1.66e-4)" "unprognostic (4.80e-2)" "unprognostic (8.97e-3)" "potential prognostic unfavorable (1.55e-5)" "potential prognostic unfavorable (3.66e-7)" "unprognostic (1.33e-3)" "unprognostic (1.86e-2)" "unprognostic (6.40e-2)" "unprognostic (3.61e-2)" "unprognostic (3.75e-1)" "unprognostic (2.84e-2)" "unprognostic (5.70e-2)" "unprognostic (6.81e-3)" "unprognostic (1.93e-2)" "unprognostic (3.39e-2)" "unprognostic (4.03e-1)" "unprognostic (1.73e-1)" "unprognostic (5.28e-1)" "unprognostic (3.44e-2)" "unprognostic (3.01e-1)" H2AZ2 "H2AFV, H2AV, MGC10170, MGC10831, MGC1947" ENSG00000105968 "H2A.Z variant histone 2" Q71UI9 7 44826791-44848087 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 651.9;Extravillous trophoblasts: 543.2;Monocyte progenitors: 514.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057236 Supported NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 8 "HPA057236: " "unprognostic (8.66e-2)" "unprognostic (5.02e-3)" "unprognostic (5.37e-3)" "unprognostic (1.69e-1)" "unprognostic (6.36e-2)" "unprognostic (6.32e-3)" "unprognostic (4.62e-1)" "unprognostic (1.66e-1)" "potential prognostic unfavorable (8.45e-5)" "potential prognostic favorable (3.77e-5)" "unprognostic (2.49e-2)" "unprognostic (1.20e-2)" "potential prognostic unfavorable (2.57e-5)" "potential prognostic unfavorable (2.32e-5)" "unprognostic (1.38e-2)" "unprognostic (8.66e-2)" "unprognostic (8.77e-2)" "unprognostic (5.36e-2)" "unprognostic (1.70e-1)" "unprognostic (6.77e-3)" "unprognostic (1.42e-1)" "unprognostic (4.31e-2)" "unprognostic (2.13e-1)" "unprognostic (1.26e-1)" "unprognostic (1.50e-2)" "unprognostic (1.07e-1)" "unprognostic (2.90e-1)" "unprognostic (3.10e-2)" "unprognostic (4.48e-1)" H2BC1 "bA317E16.3, H2BFU, HIST1H2BA, STBP, TSH2B" ENSG00000146047 "H2B clustered histone 1" Q96A08 6 25726777-25727345 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 50 "testis: 5.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB011603, HPA042205, HPA043013" Enhanced NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 4: Non-specific - Transcription" 65 "CAB011603: , HPA042205: , HPA043013: " H2BC10 "H2B/k, H2BFK, HIST1H2BI" ENSG00000278588 "H2B clustered histone 10" P62807 6 26272931-26273412 "Plasma proteins, Predicted intracellular proteins" "Antibiotic, Antimicrobial, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 2.0;choroid plexus: 2.2;lymphoid tissue: 2.0" "Cell type enhanced" "Detected in some" "Erythrocyte progenitors: 19.7;Erythrocytes: 6.1;Gastric progenitor cells: 5.1;Megakaryocyte progenitors: 11.4;Monocyte progenitors: 17.4;Plasma cells: 5.1;Tuft cells: 11.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder Urothelial Carcinoma (TCGA): 5.2;Colon Adenocarcinoma (TCGA): 8.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in some" "HPA042205, HPA043013, HPA048671" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 25: Non-specific - Transcription" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 10 Nucleoplasm Cytosol "HPA042205: , HPA043013: , HPA048671: " "unprognostic (4.10e-2)" "unprognostic (9.26e-2)" "unprognostic (4.71e-2)" "unprognostic (1.08e-1)" "unprognostic (2.77e-2)" "unprognostic (5.13e-2)" "unprognostic (2.38e-1)" H2BC11 "H2B/r, H2BFR, HIST1H2BJ" ENSG00000124635 "H2B clustered histone 11" P06899 6 27125897-27132795 "Essential proteins, Predicted intracellular proteins" "Antibiotic, Antimicrobial, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 30.2" "Cell type enriched" "Detected in many" 14 "Platelets: 1971.2" "Group enriched" "Detected in some" 6 "central nervous system macrophage: 17.7;endothelial cell: 8.1;leukocyte: 9.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "neutrophil: 16.3" "Lineage enriched" "Detected in many" 5 "granulocytes: 16.3" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Skin - Outer root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042205, HPA043013, HPA048671" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 39: Testis - Nuclear processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 47: Platelets - Hemostasis" 48 Nucleoplasm Cytosol "HPA042205: , HPA043013: , HPA048671: " "unprognostic (1.72e-2)" "unprognostic (6.41e-2)" "potential prognostic favorable (1.85e-4)" "unprognostic (1.58e-1)" "unprognostic (1.52e-1)" "unprognostic (6.06e-3)" "unprognostic (2.78e-1)" "unprognostic (2.34e-2)" "potential prognostic unfavorable (3.97e-4)" "unprognostic (1.72e-2)" "unprognostic (3.14e-2)" "potential prognostic unfavorable (2.69e-4)" "unprognostic (2.25e-1)" "unprognostic (2.24e-2)" "unprognostic (2.15e-3)" "unprognostic (1.11e-1)" "unprognostic (2.76e-2)" "unprognostic (8.20e-2)" "unprognostic (4.08e-1)" "unprognostic (3.57e-3)" "unprognostic (3.15e-1)" "unprognostic (2.61e-1)" "unprognostic (3.39e-2)" "unprognostic (1.84e-2)" "unprognostic (3.20e-1)" "unprognostic (5.50e-2)" "unprognostic (5.62e-2)" "unprognostic (2.47e-2)" "unprognostic (1.01e-1)" H2BC12 "H2BFAiii, H2BFT, HIST1H2BK" ENSG00000197903 "H2B clustered histone 12" O60814 6 27146361-27146855 "Essential proteins, Predicted intracellular proteins" "Antibiotic, Antimicrobial, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 42.0;Megakaryocyte progenitors: 21.8;Megakaryocytes: 24.7;Monocyte progenitors: 25.5;Neutrophil progenitors: 11.9;Oocytes: 18.4;Platelets: 32.4;Tuft cells: 57.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Testis - Sertoli cells" "HPA042205, HPA043013, HPA048671" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 70: Non-specific - Protein processing" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 47 Nucleoplasm Cytosol "HPA042205: , HPA043013: , HPA048671: " "unprognostic (1.08e-2)" "unprognostic (2.85e-1)" "unprognostic (1.64e-3)" "unprognostic (1.30e-1)" "unprognostic (2.35e-1)" "unprognostic (5.06e-1)" "unprognostic (5.69e-1)" "unprognostic (1.63e-1)" "unprognostic (5.98e-2)" "unprognostic (1.68e-1)" "unprognostic (4.52e-2)" "unprognostic (1.21e-3)" "unprognostic (2.84e-1)" "potential prognostic unfavorable (8.48e-4)" "unprognostic (3.39e-2)" "unprognostic (6.00e-2)" "unprognostic (1.17e-2)" "unprognostic (2.48e-3)" "unprognostic (8.18e-2)" "unprognostic (4.27e-3)" "unprognostic (1.74e-1)" "unprognostic (4.86e-2)" "unprognostic (1.22e-2)" "unprognostic (6.79e-2)" "unprognostic (1.28e-1)" "unprognostic (1.21e-2)" "unprognostic (4.76e-2)" "unprognostic (6.55e-2)" "unprognostic (2.10e-1)" H2BC12L "H2BFS, H2BS1" ENSG00000234289 "H2B clustered histone 12 like" P57053 21 43565182-43565648 "Predicted intracellular proteins" "Antibiotic, Antimicrobial, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "gallbladder: 1.9;lymphoid tissue: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "Adrenocortical cancer: 4.9" "Not detected" "Not detected" "HPA042205, HPA043013, HPA048671" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 55: Lymphoma - Immune response" Nucleoplasm Cytosol "HPA042205: , HPA043013: , HPA048671: " "unprognostic (1.17e-2)" "unprognostic (2.16e-1)" "unprognostic (6.81e-2)" H2BC13 "dJ97D16.4, H2B/c, H2BFC, HIST1H2BL" ENSG00000185130 "H2B clustered histone 13" Q99880 6 27807479-27807929 "Essential proteins, Plasma proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "bone marrow: 6.6" "Cell type enhanced" "Detected in some" "Erythrocyte progenitors: 32.2;Megakaryocyte progenitors: 20.7;Megakaryocytes: 6.2;Monocyte progenitors: 21.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 7.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.4" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "HPA042205, HPA043013, HPA048671" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 2: Neurons - Nucleosome" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 44 Nucleoplasm Cytosol "HPA042205: , HPA043013: , HPA048671: " "unprognostic (6.40e-3)" "unprognostic (2.35e-1)" "unprognostic (2.02e-1)" "unprognostic (3.88e-1)" "unprognostic (1.47e-1)" "unprognostic (2.90e-2)" "unprognostic (4.26e-2)" "unprognostic (2.09e-1)" "unprognostic (1.12e-1)" "unprognostic (4.12e-2)" "unprognostic (2.99e-2)" "unprognostic (2.06e-1)" "unprognostic (5.43e-2)" H2BC14 "dJ160A22.3, H2B/e, H2BFE, HIST1H2BM" ENSG00000273703 "H2B clustered histone 14" Q99879 6 27815022-27815489 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 3.3;choroid plexus: 1.9;lymphoid tissue: 2.9" "Cell type enhanced" "Detected in some" "Erythrocyte progenitors: 37.1;Erythrocytes: 8.9;Megakaryocyte progenitors: 15.9;Monocyte progenitors: 14.8;Neutrophil progenitors: 3.2;Plasma cells: 4.2;Tuft cells: 11.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 3.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "HPA042205, HPA043013, HPA048671" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 9 Nucleoplasm Cytosol "HPA042205: , HPA043013: , HPA048671: " "unprognostic (1.09e-2)" "unprognostic (2.55e-1)" "unprognostic (1.43e-2)" "unprognostic (2.67e-3)" "unprognostic (1.13e-1)" "unprognostic (9.12e-2)" "unprognostic (5.10e-2)" "unprognostic (5.19e-1)" "unprognostic (2.91e-1)" H2BC15 "H2B/d, H2BFD, HIST1H2BN" ENSG00000233822 "H2B clustered histone 15" Q99877 6 27838545-27855709 "Essential proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Breast lactating cells: 52.9;Enterocytes: 54.1;Erythrocyte progenitors: 76.9;Megakaryocyte progenitors: 69.5;Megakaryocyte-Erythroid progenitors: 66.4;Monocyte progenitors: 88.1;Plasma cells: 62.3;Platelets: 105.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 16.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Prostate - Prostate glandular cells" "HPA042205, HPA043013, HPA048671" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 34: Non-specific - Mixed function" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 65: Non-specific - Cell growth & division" 9 Nucleoplasm Cytosol "HPA042205: , HPA043013: , HPA048671: " "unprognostic (2.02e-2)" "unprognostic (1.53e-1)" "unprognostic (3.99e-2)" "unprognostic (1.18e-2)" "unprognostic (1.10e-1)" "unprognostic (1.28e-1)" "unprognostic (2.75e-1)" "unprognostic (2.46e-2)" "unprognostic (4.95e-2)" "unprognostic (2.14e-1)" "unprognostic (1.98e-1)" "unprognostic (1.08e-1)" "unprognostic (8.60e-2)" "unprognostic (4.48e-1)" "unprognostic (3.60e-1)" "unprognostic (9.95e-3)" "unprognostic (9.83e-2)" "unprognostic (4.83e-1)" "unprognostic (3.60e-1)" "unprognostic (2.57e-1)" "unprognostic (2.88e-1)" "unprognostic (1.46e-1)" H2BC17 "H2B.2, H2B/n, H2BFN, HIST1H2BO" ENSG00000274641 "H2B clustered histone 17" P23527 6 27893425-27893891 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 2.3;lymphoid tissue: 2.4" "Cell type enhanced" "Detected in some" "Erythrocyte progenitors: 38.7;Megakaryocyte progenitors: 18.0;Megakaryocyte-Erythroid progenitors: 3.2;Monocyte progenitors: 20.6;Neutrophil progenitors: 9.4;Platelets: 11.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 10.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "HPA042205, HPA043013, HPA048671" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 27 Nucleoplasm Cytosol "HPA042205: , HPA043013: , HPA048671: " "unprognostic (2.47e-2)" "unprognostic (6.52e-2)" "unprognostic (1.55e-2)" "unprognostic (4.20e-2)" "unprognostic (2.32e-1)" "unprognostic (4.89e-2)" "unprognostic (4.78e-2)" "potential prognostic unfavorable (1.95e-4)" "unprognostic (2.94e-2)" "unprognostic (3.65e-3)" "unprognostic (1.07e-1)" "unprognostic (1.98e-2)" "unprognostic (1.53e-2)" "unprognostic (2.31e-1)" "unprognostic (6.09e-2)" "unprognostic (4.42e-1)" "unprognostic (6.79e-2)" H2BC18 HIST2H2BF ENSG00000203814 "H2B clustered histone 18" Q5QNW6 1 149782689-149812373 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 76.7;Epididymal principal cells: 54.1;Erythrocyte progenitors: 49.7;Microglia: 88.6;Prostatic club cells: 81.7;Prostatic hillock cells: 64.3;Tuft cells: 57.6" "Cell type enriched" "Detected in many" 4 "central nervous system macrophage: 91.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 8 "neutrophil: 45.4" "Lineage enriched" "Detected in all" 8 "granulocytes: 45.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB007814, HPA042205, HPA043013, HPA048671" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 64: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 65: Non-specific - Cell growth & division" 15 Nucleoplasm Cytosol "CAB007814: , HPA042205: , HPA043013: , HPA048671: " "unprognostic (1.62e-2)" "unprognostic (4.95e-2)" "potential prognostic favorable (9.88e-4)" "unprognostic (3.92e-3)" "unprognostic (3.77e-3)" "unprognostic (1.06e-1)" "unprognostic (3.68e-2)" "unprognostic (1.68e-1)" "unprognostic (8.32e-2)" "validated prognostic unfavorable (8.16e-4)" "validated prognostic unfavorable (4.97e-4)" "unprognostic (8.68e-2)" "potential prognostic unfavorable (9.72e-5)" "unprognostic (2.65e-2)" "unprognostic (2.02e-1)" "unprognostic (7.34e-3)" "unprognostic (8.89e-2)" "potential prognostic unfavorable (1.07e-4)" "unprognostic (1.51e-1)" "unprognostic (7.81e-2)" "unprognostic (1.92e-2)" "unprognostic (4.01e-3)" "unprognostic (4.19e-2)" "unprognostic (4.75e-2)" "unprognostic (1.67e-2)" "unprognostic (1.31e-1)" H2BC21 "H2B, H2B-GL105, H2B.1, H2B/q, H2BE, H2BFQ, HIST2H2BE" ENSG00000184678 "H2B clustered histone 21" Q16778 1 149884459-149886682 "Essential proteins, Predicted intracellular proteins" "Antibiotic, Antimicrobial, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 243.7;Esophageal apical cells: 114.5;Platelets: 531.6;Syncytiotrophoblasts: 249.5;Tuft cells: 172.9" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 34.3" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 134.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 58.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 58.7" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "HPA042205, HPA043013, HPA048671" Supported Approved Nucleoplasm,Cytosol NA Yes "Cluster 35: Neutrophils - Protein binding" "Cluster 74: Non-specific - Signal transduction" "Cluster 11: White matter - Signal transduction" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 47: Platelets - Hemostasis" 137 Nucleoplasm Cytosol "HPA042205: , HPA043013: , HPA048671: " "unprognostic (1.74e-2)" "unprognostic (1.35e-1)" "unprognostic (1.19e-1)" "potential prognostic unfavorable (3.82e-4)" "unprognostic (3.31e-2)" "unprognostic (2.19e-1)" "unprognostic (1.46e-2)" "unprognostic (1.23e-1)" "unprognostic (3.02e-3)" "unprognostic (1.36e-1)" "unprognostic (2.23e-1)" "unprognostic (6.98e-2)" "unprognostic (2.53e-1)" "unprognostic (3.25e-1)" "unprognostic (1.19e-3)" "unprognostic (1.42e-1)" "unprognostic (2.57e-2)" "unprognostic (1.32e-1)" "unprognostic (1.75e-2)" "unprognostic (1.37e-1)" "unprognostic (2.19e-1)" "unprognostic (2.10e-1)" "unprognostic (2.76e-3)" "unprognostic (1.54e-2)" "unprognostic (6.63e-2)" "unprognostic (2.28e-2)" "unprognostic (1.78e-1)" "unprognostic (8.27e-2)" "unprognostic (5.91e-2)" H2BC26 "H2BU1, HIST3H2BB" ENSG00000196890 "H2B clustered histone 26" Q8N257 1 228458103-228463104 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.1;choroid plexus: 3.4" "Group enriched" "Detected in some" 4 "Brain excitatory neurons: 3.3;Brain inhibitory neurons: 2.4;Microglia: 4.1;Other brain neurons: 3.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 2.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Kidney - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA042205, HPA043013, HPA048671" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 27: Cerebellum - Synaptic function" "Cluster 1: Neurons - Mixed function" "Cluster 20: Myeloma - Immune response" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 44 Nucleoplasm Cytosol "HPA042205: , HPA043013: , HPA048671: " "unprognostic (4.14e-2)" "unprognostic (7.16e-3)" "unprognostic (6.69e-2)" "potential prognostic favorable (6.67e-5)" "unprognostic (2.25e-1)" "unprognostic (5.59e-2)" "unprognostic (4.06e-2)" "unprognostic (1.74e-1)" "unprognostic (3.55e-3)" "unprognostic (1.08e-2)" H2BC3 "H2B/f, H2BFF, HIST1H2BB" ENSG00000276410 "H2B clustered histone 3" P33778 6 26043227-26043713 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 1.0;lymphoid tissue: 1.0;testis: 1.2" "Cell type enhanced" "Detected in some" "Erythrocyte progenitors: 57.0;Erythrocytes: 10.5;Megakaryocyte progenitors: 24.4;Megakaryocyte-Erythroid progenitors: 10.3;Monocyte progenitors: 29.7;Neutrophil progenitors: 7.1;Plasma cells: 7.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Colon Adenocarcinoma (TCGA): 4.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 6.4" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "HPA042205, HPA043013, HPA048671" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 44: Non-specific - Mixed function" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 52 Nucleoplasm Cytosol "HPA042205: , HPA043013: , HPA048671: " "unprognostic (6.34e-1)" "unprognostic (4.99e-1)" "unprognostic (1.34e-1)" "unprognostic (2.00e-1)" "unprognostic (1.38e-1)" H2BC4 "H2B.1, H2B/l, H2BFL, HIST1H2BC" ENSG00000180596 "H2B clustered histone 4" P62807 6 26114873-26123926 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Antibiotic, Antimicrobial, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 143.0;Esophageal apical cells: 306.3;Neutrophils: 116.2;Plasma cells: 114.0;Platelets: 492.4" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 19.6;oligodendrocyte: 16.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 18 "neutrophil: 1084.4" "Lineage enriched" "Detected in all" 25 "granulocytes: 1084.4" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "HPA042205, HPA043013, HPA048671" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Ribosome" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 47: Platelets - Hemostasis" 25 Nucleoplasm Cytosol "HPA042205: , HPA043013: , HPA048671: " "unprognostic (1.60e-1)" "unprognostic (9.82e-3)" "unprognostic (7.96e-3)" "unprognostic (7.37e-3)" "unprognostic (1.22e-2)" "unprognostic (3.74e-2)" "unprognostic (2.40e-1)" "unprognostic (1.13e-1)" "unprognostic (3.19e-2)" "unprognostic (9.82e-2)" "unprognostic (7.85e-2)" "potential prognostic unfavorable (5.56e-4)" "unprognostic (4.06e-1)" "potential prognostic unfavorable (2.12e-4)" "unprognostic (2.10e-3)" "unprognostic (2.29e-2)" "unprognostic (2.03e-2)" "unprognostic (1.98e-1)" "unprognostic (1.10e-1)" "unprognostic (1.26e-3)" "unprognostic (1.92e-1)" "unprognostic (3.89e-1)" "unprognostic (1.24e-1)" "unprognostic (1.54e-1)" "unprognostic (1.08e-1)" "unprognostic (5.40e-2)" "unprognostic (1.56e-1)" "unprognostic (2.08e-1)" "unprognostic (3.18e-1)" H2BC5 "H2B/b, H2BFB, HIST1H2BD" ENSG00000158373 "H2B clustered histone 5" P58876 6 26158122-26171349 "Essential proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 287.7;Colonocytes: 215.5;Epididymal principal cells: 191.6;Esophageal apical cells: 208.9;Plasma cells: 189.7;Platelets: 270.0;Prostatic club cells: 449.9;Prostatic hillock cells: 202.2" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 53.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA042205, HPA043013, HPA048671, CAB062336" Supported Approved Nucleoplasm,Cytosol NA Yes "Cluster 24: Non-specific - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 65: Non-specific - Cell growth & division" 79 Nucleoplasm Cytosol "CAB062336: , HPA042205: , HPA043013: , HPA048671: " "unprognostic (9.55e-2)" "unprognostic (1.85e-1)" "unprognostic (1.05e-2)" "unprognostic (6.74e-2)" "unprognostic (1.74e-1)" "unprognostic (1.51e-1)" "unprognostic (3.55e-2)" "unprognostic (6.31e-2)" "unprognostic (2.83e-3)" "unprognostic (9.41e-2)" "unprognostic (4.12e-1)" "unprognostic (5.93e-2)" "unprognostic (1.48e-1)" "unprognostic (5.83e-3)" "potential prognostic unfavorable (2.49e-4)" "unprognostic (1.76e-1)" "unprognostic (1.01e-2)" "unprognostic (9.07e-2)" "unprognostic (3.96e-1)" "unprognostic (1.88e-3)" "unprognostic (7.40e-2)" "unprognostic (7.88e-2)" "unprognostic (2.11e-3)" "unprognostic (1.77e-1)" "unprognostic (4.27e-1)" "unprognostic (9.44e-2)" "unprognostic (1.38e-1)" "unprognostic (6.03e-2)" "unprognostic (2.69e-3)" H2BC6 "H2B.h, H2B/h, H2BFH, HIST1H2BE" ENSG00000274290 "H2B clustered histone 6" P62807 6 26172059-26184655 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Antibiotic, Antimicrobial, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Prostatic club cells: 72.4;Prostatic hillock cells: 35.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "HPA042205, HPA043013, HPA048671" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 65: Non-specific - Cell growth & division" 10 Nucleoplasm Cytosol "HPA042205: , HPA043013: , HPA048671: " "unprognostic (3.24e-2)" "unprognostic (1.61e-1)" "unprognostic (1.30e-1)" "unprognostic (1.04e-2)" "unprognostic (1.09e-1)" "unprognostic (3.18e-1)" "unprognostic (6.95e-2)" "unprognostic (2.62e-2)" "unprognostic (1.92e-1)" "unprognostic (6.35e-3)" "unprognostic (2.01e-3)" "unprognostic (1.48e-1)" "unprognostic (2.13e-3)" "unprognostic (1.70e-1)" "unprognostic (1.47e-2)" "unprognostic (5.93e-2)" "unprognostic (8.45e-3)" "unprognostic (3.14e-1)" "unprognostic (1.82e-1)" "unprognostic (5.01e-2)" "unprognostic (3.13e-1)" "unprognostic (2.00e-1)" H2BC7 "H2B/g, H2BFG, HIST1H2BF" ENSG00000277224 "H2B clustered histone 7" P62807 6 26199516-26199988 "Plasma proteins, Predicted intracellular proteins" "Antibiotic, Antimicrobial, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 8.2;prostate: 8.0" "Cell type enhanced" "Detected in some" "Erythrocyte progenitors: 121.9;Erythrocytes: 24.0;Hematopoietic stem cells: 28.6;Megakaryocyte progenitors: 55.7;Megakaryocyte-Erythroid progenitors: 23.1;Megakaryocytes: 30.9;Microglia: 16.4;Monocyte progenitors: 61.3;Plasma cells: 14.6;Thymocytes: 15.2;Tuft cells: 34.6" "Cell type enriched" "Detected in some" 9 "central nervous system macrophage: 23.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Thyroid gland - T-cells" "HPA042205, HPA043013, HPA048671" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 25: Non-specific - Transcription" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 9 Nucleoplasm Cytosol "HPA042205: , HPA043013: , HPA048671: " "unprognostic (1.05e-1)" "unprognostic (1.49e-2)" "unprognostic (1.94e-1)" "unprognostic (2.00e-1)" "unprognostic (1.48e-2)" "unprognostic (4.29e-3)" "unprognostic (1.05e-1)" "unprognostic (1.87e-3)" "unprognostic (3.54e-1)" "unprognostic (5.26e-3)" "unprognostic (7.58e-2)" "unprognostic (7.95e-3)" "unprognostic (1.18e-1)" H2BC8 "H2B.1A, H2B/a, H2BFA, HIST1H2BG" ENSG00000273802 "H2B clustered histone 8" P62807 6 26216200-26216688 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Antibiotic, Antimicrobial, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 45.1;Esophageal apical cells: 53.4;Hematopoietic stem cells: 22.3;Microglia: 20.7;Plasma cells: 32.5;Platelets: 147.0;Tuft cells: 57.6" "Group enriched" "Detected in some" 7 "central nervous system macrophage: 26.7;leukocyte: 6.9" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 27.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Outer root sheath cells, Thyroid gland - T-cells" "HPA042205, HPA043013, HPA048671" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 47: Platelets - Hemostasis" 156 Nucleoplasm Cytosol "HPA042205: , HPA043013: , HPA048671: " "unprognostic (7.79e-2)" "unprognostic (6.74e-3)" "unprognostic (5.72e-2)" "unprognostic (2.15e-2)" "unprognostic (3.89e-1)" "unprognostic (1.11e-1)" "unprognostic (6.46e-2)" "potential prognostic unfavorable (2.58e-4)" "potential prognostic unfavorable (4.82e-5)" "unprognostic (1.17e-1)" "unprognostic (1.73e-1)" "unprognostic (4.99e-3)" "unprognostic (1.29e-1)" "unprognostic (2.37e-1)" "unprognostic (3.09e-1)" "unprognostic (1.56e-2)" "unprognostic (1.67e-1)" "unprognostic (2.04e-2)" "unprognostic (4.21e-2)" "unprognostic (6.27e-2)" "unprognostic (1.04e-1)" "unprognostic (7.93e-2)" "unprognostic (7.34e-2)" "unprognostic (1.31e-1)" "unprognostic (1.87e-1)" "unprognostic (2.03e-2)" H2BC9 "H2B/j, H2BFJ, HIST1H2BH" ENSG00000275713 "H2B clustered histone 9" Q93079 6 26251614-26252075 "Essential proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 8.6;lymphoid tissue: 10.7" "Cell type enhanced" "Detected in many" "Endometrial luminal cells: 18.0;Erythrocyte progenitors: 105.6;Erythrocytes: 17.8;Esophageal apical cells: 18.3;Extravillous trophoblasts: 34.6;Megakaryocyte progenitors: 51.6;Monocyte progenitors: 52.1;Platelets: 79.0" "Group enriched" "Detected in some" 12 "central nervous system macrophage: 6.4;leukocyte: 4.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 18.4;neutrophil: 14.4" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Prostate - Urothelial cells" "HPA042205, HPA043013, HPA048671" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 50 Nucleoplasm Cytosol "HPA042205: , HPA043013: , HPA048671: " "unprognostic (9.62e-3)" "unprognostic (7.32e-2)" "potential prognostic favorable (5.42e-4)" "unprognostic (4.04e-2)" "unprognostic (1.43e-1)" "unprognostic (1.03e-3)" "unprognostic (4.04e-1)" "potential prognostic favorable (9.03e-4)" "unprognostic (1.62e-2)" "unprognostic (5.08e-2)" "unprognostic (1.39e-2)" "unprognostic (2.06e-2)" "unprognostic (1.42e-1)" "unprognostic (1.33e-1)" "unprognostic (1.57e-1)" H2BK1 H2BE1 ENSG00000285480 "H2B.K variant histone 1" A0A2R8Y619 7 151207837-151210488 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in single" "skin 1: 3.1" "Cell type enriched" "Detected in some" 8 "Oocytes: 9.2" "Cell type enhanced" "Detected in single" "leukocyte: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Myeloma: 1.9" "Low region specificity" "Detected in all" HPA043013 Uncertain NA NA "Cluster 37: Skin - Keratinization" "Cluster 6: Non-specific - Immune response" "Cluster 35: RS4;11 - Unknown function" "Cluster 102: Non-specific - Mixed function" "HPA043013: " H2BN1 ENSG00000290320 "H2B.N variant histone 1" 17 32895433-32906586 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 23: Choroid plexus - Mixed function" "Cluster 20: Myeloma - Immune response" H2BW1 "H2BFWT, TH2B-175" ENSG00000123569 "H2B.W histone 1" Q7Z2G1 X 104011147-104013708 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Differentiating spermatogonia: 3.2;Early primary spermatocytes: 6.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA056289 Uncertain NA NA "Cluster 56: Non-specific - Sensory perception" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 9 "HPA056289: " H2BW2 "H2BFM, H2BM" ENSG00000101812 "H2B.W histone 2" P0C1H6 X 104039956-104042454 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 2.6" "Group enriched" "Detected in some" 12 "Early primary spermatocytes: 11.2;Early spermatids: 6.7;Late primary spermatocytes: 10.1;Late spermatids: 14.9" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Glioblastoma Multiforme (TCGA): 1.7" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 35: RS4;11 - Unknown function" "Cluster 3: Early primary spermatocytes - Early meiosis" "unprognostic (1.73e-1)" H3-3A "H3.3A, H3F3, H3F3A" ENSG00000163041 "H3.3 histone A" P84243 1 226061851-226072019 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" DNA-binding "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Megakaryocytes: 500.7;Neutrophils: 835.2;Platelets: 816.9" "Cell type enhanced" "Detected in all" "leukocyte: 68.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 4496.2" "Lineage enriched" "Detected in all" 4 "granulocytes: 4496.2" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "CAB011481, CAB037178, HPA042570, HPA050968, HPA064058" Supported Supported Nucleoplasm NA NA 40000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 178 Nucleoplasm "CAB011481: , CAB037178: , HPA042570: , HPA050968: , HPA064058: " "unprognostic (2.36e-2)" "unprognostic (1.70e-1)" "unprognostic (1.05e-2)" "unprognostic (2.15e-1)" "unprognostic (7.49e-2)" "unprognostic (2.32e-2)" "unprognostic (1.81e-3)" "unprognostic (6.78e-2)" "unprognostic (1.52e-1)" "unprognostic (4.18e-2)" "unprognostic (4.42e-2)" "unprognostic (8.94e-2)" "unprognostic (4.05e-3)" "unprognostic (2.87e-1)" "unprognostic (7.66e-2)" "unprognostic (9.48e-2)" "unprognostic (2.89e-1)" "unprognostic (8.36e-2)" "unprognostic (2.69e-3)" "unprognostic (2.32e-1)" "unprognostic (1.75e-1)" "unprognostic (2.38e-1)" "unprognostic (1.54e-1)" "unprognostic (1.43e-2)" "unprognostic (3.80e-2)" "unprognostic (7.21e-2)" "unprognostic (1.69e-1)" "unprognostic (2.23e-1)" "unprognostic (4.86e-2)" H3-3B "H3.3B, H3F3B" ENSG00000132475 "H3.3 histone B" P84243 17 75776434-75785893 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" DNA-binding "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 3984.2" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 11340.1;Esophageal suprabasal cells: 4929.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 21235.8" "Lineage enriched" "Detected in all" 6 "granulocytes: 21235.8" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "CAB037166, CAB037187, CAB037221, HPA042570, HPA050968, HPA064058" Supported Enhanced Nucleoplasm NA Yes 40000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 55: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 20: Non-specific - Transcription regulation" 46 Nucleoplasm "CAB037166: , CAB037187: , CAB037221: , HPA042570: , HPA050968: , HPA064058: " "unprognostic (3.11e-1)" "unprognostic (7.79e-2)" "unprognostic (1.36e-1)" "unprognostic (1.36e-2)" "unprognostic (8.34e-3)" "unprognostic (6.89e-2)" "unprognostic (9.11e-2)" "unprognostic (1.05e-1)" "unprognostic (2.53e-2)" "unprognostic (3.19e-3)" "unprognostic (4.00e-2)" "unprognostic (1.34e-2)" "unprognostic (2.44e-2)" "unprognostic (7.96e-2)" "unprognostic (2.44e-2)" "unprognostic (5.76e-2)" "unprognostic (1.33e-1)" "unprognostic (1.24e-1)" "unprognostic (2.06e-1)" "unprognostic (5.32e-3)" "unprognostic (2.16e-1)" "unprognostic (1.47e-2)" "unprognostic (4.06e-1)" "unprognostic (1.81e-1)" "unprognostic (1.83e-1)" "unprognostic (1.18e-1)" "unprognostic (1.78e-1)" "unprognostic (1.32e-1)" "unprognostic (1.54e-1)" H3-4 "H3.4, H3/g, H3C16, H3FT, H3t, HIST3H3" ENSG00000168148 "H3.4 histone, cluster member" Q16695 1 228424845-228425360 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 16 "testis: 3.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB001386, CAB003812, HPA042570, HPA050968, HPA064058" Approved Supported Nucleoplasm NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 37: Neurons - Mixed function" "Cluster 56: Non-specific - Sensory perception" 137 Nucleoplasm "CAB001386: , CAB003812: , HPA042570: , HPA050968: , HPA064058: " H3-5 "H3.3C, H3.5, H3F3C" ENSG00000188375 "H3.5 histone" Q6NXT2 12 31791185-31792298 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "testis: 19.8" "Group enriched" "Detected in some" 11 "Early spermatids: 100.3;Late primary spermatocytes: 230.8" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Uterine Corpus Endometrial Carcinoma (TCGA): 1.1" "Not detected" "Not detected" "Low immune cell specificity" "Detected in all" "Lineage enriched" "Detected in all" 5 "granulocytes: 73.3" "Low cancer specificity" "Detected in single" "Testis - Early spermatids" "Low region specificity" "Detected in all" "HPA042570, HPA050968, HPA064058" Approved Supported Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 57: Testis - Spermatogenesis" "Cluster 61: BICR 18 - Protein kinases" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 24 Nucleoplasm "HPA042570: , HPA050968: , HPA064058: " "unprognostic (1.42e-3)" "unprognostic (1.40e-2)" "unprognostic (7.40e-2)" H3-7 "H3-2, H3.7, HIST2H3PS2, p06" ENSG00000273213 "H3.7 histone (putative)" Q5TEC6 1 143894544-143905977 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 23.7" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 1.7;Lacrimal acinar cells: 1.8;Melanocytes: 1.0;Microglia: 2.2;Mucous neck cells: 2.0;Ovarian stromal cells: 2.1" "Cell type enriched" "Detected in single" 4 "central nervous system macrophage: 3.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "neutrophil: 9.8" "Lineage enriched" "Detected in many" 6 "granulocytes: 9.8" "Low cancer specificity" "Detected in many" "HPA042570, HPA050968, HPA064058" Approved Supported Nucleoplasm NA NA 12000000 "Cluster 35: Neutrophils - Protein binding" "Cluster 75: Ovary - Mixed function" "Cluster 25: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 29 Nucleoplasm "HPA042570: , HPA050968: , HPA064058: " "unprognostic (1.01e-1)" "unprognostic (5.77e-2)" "unprognostic (6.87e-2)" "unprognostic (2.39e-1)" "unprognostic (1.78e-1)" "unprognostic (1.30e-2)" "unprognostic (5.05e-2)" "unprognostic (7.97e-2)" "unprognostic (4.45e-1)" "unprognostic (1.00e-2)" "unprognostic (1.45e-2)" "unprognostic (6.21e-3)" "unprognostic (1.93e-1)" "unprognostic (1.93e-2)" "unprognostic (5.72e-2)" "unprognostic (1.78e-1)" "unprognostic (1.48e-1)" "unprognostic (3.33e-1)" "unprognostic (1.27e-1)" "unprognostic (1.78e-1)" "unprognostic (3.87e-2)" H3C1 "H3/A, H3FA, HIST1H3A" ENSG00000275714 "H3 clustered histone 1" P68431 6 26020451-26020958 "Disease related genes, Predicted intracellular proteins" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 7.4;testis: 3.3" "Cell type enriched" "Detected in many" 4 "Tuft cells: 69.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "HPA042570, HPA050968, HPA064058" Approved Supported Nucleoplasm NA NA 57000000 "Cluster 33: Non-specific - ATP binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 2: Neurons - Nucleosome" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 20: Non-specific - Transcription regulation" 393 Nucleoplasm "HPA042570: , HPA050968: , HPA064058: " "unprognostic (1.71e-1)" "unprognostic (1.35e-1)" "unprognostic (7.66e-2)" "unprognostic (7.36e-2)" "unprognostic (6.76e-2)" "unprognostic (6.41e-3)" "unprognostic (2.17e-1)" "unprognostic (2.97e-1)" H3C10 "H3/k, H3F1K, H3FK, HIST1H3H" ENSG00000278828 "H3 clustered histone 10" P68431 6 27810051-27811300 "Disease related genes, Predicted intracellular proteins" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 14 "Platelets: 1032.0" "Group enriched" "Detected in some" 4 "central nervous system macrophage: 2.0;choroid plexus epithelial cell: 2.8;leukocyte: 2.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "basophil: 115.9;neutrophil: 51.1" "Lineage enriched" "Detected in all" 9 "granulocytes: 115.9" "Low cancer specificity" "Detected in all" "HPA042570, HPA050968, HPA064058" Approved Supported Nucleoplasm NA Yes 57000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 23: Choroid plexus - Mixed function" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 47: Platelets - Hemostasis" 72 Nucleoplasm "HPA042570: , HPA050968: , HPA064058: " "potential prognostic unfavorable (6.77e-6)" "unprognostic (1.72e-1)" "potential prognostic favorable (8.82e-4)" "unprognostic (5.21e-2)" "unprognostic (1.11e-1)" "unprognostic (1.21e-1)" "unprognostic (2.65e-1)" "unprognostic (3.32e-1)" "unprognostic (2.95e-1)" "unprognostic (6.43e-2)" "potential prognostic unfavorable (4.61e-7)" "unprognostic (2.28e-1)" "unprognostic (1.74e-2)" "unprognostic (4.39e-2)" "unprognostic (1.11e-2)" "unprognostic (1.32e-3)" "unprognostic (9.59e-2)" "potential prognostic unfavorable (5.14e-6)" "unprognostic (1.81e-1)" "unprognostic (1.60e-1)" "unprognostic (2.14e-2)" "unprognostic (2.38e-1)" "unprognostic (2.48e-1)" "unprognostic (1.73e-1)" "unprognostic (2.22e-1)" "unprognostic (2.04e-2)" H3C11 "H3.f, H3/f, H3FF, HIST1H3I" ENSG00000275379 "H3 clustered histone 11" P68431 6 27871845-27872346 "Disease related genes, Predicted intracellular proteins" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "bone marrow: 1.2" "Group enriched" "Detected in some" 4 "Erythrocyte progenitors: 43.5;Megakaryocyte progenitors: 22.6;Monocyte progenitors: 18.6;Tuft cells: 34.6" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Colon Adenocarcinoma (TCGA): 3.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 8.3" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in some" "HPA042570, HPA050968, HPA064058" Approved Supported Nucleoplasm NA NA 57000000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 72 Nucleoplasm "HPA042570: , HPA050968: , HPA064058: " "unprognostic (7.96e-3)" "unprognostic (4.41e-2)" "unprognostic (1.46e-1)" "unprognostic (1.82e-1)" "unprognostic (9.12e-2)" "unprognostic (4.04e-1)" "unprognostic (2.86e-3)" "unprognostic (1.93e-1)" H3C12 "H3/j, H3FJ, HIST1H3J" ENSG00000197153 "H3 clustered histone 12" P68431 6 27890315-27893106 "Disease related genes, Predicted intracellular proteins" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 1.2;lymphoid tissue: 1.0" "Cell type enhanced" "Detected in many" "Colonocytes: 167.0;Cytotrophoblasts: 39.7;Enterocytes: 127.6;Erythrocyte progenitors: 59.0;Goblet cells: 82.3;Hofbauer cells: 37.9;Megakaryocyte progenitors: 50.8;Monocyte progenitors: 54.4;Paneth cells: 42.5;Plasma cells: 40.8;Platelets: 67.9;Syncytiotrophoblasts: 62.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Colon Adenocarcinoma (TCGA): 5.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "HPA042570, HPA050968, HPA064058" Approved Supported Nucleoplasm NA NA 57000000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 65: Non-specific - Cell growth & division" 73 Nucleoplasm "HPA042570: , HPA050968: , HPA064058: " "unprognostic (1.70e-2)" "unprognostic (1.76e-1)" "unprognostic (1.58e-1)" "unprognostic (2.56e-1)" "unprognostic (2.70e-1)" "unprognostic (1.64e-2)" "unprognostic (6.46e-3)" "unprognostic (7.49e-2)" "unprognostic (3.10e-2)" "unprognostic (2.61e-1)" H3C13 HIST2H3D ENSG00000183598 "H3 clustered histone 13" Q71DI3 1 149813225-149813693 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 3.3" "Cell type enhanced" "Detected in some" "B-cells: 1.6;Cardiomyocytes: 2.7;Erythrocyte progenitors: 6.0;Megakaryocyte progenitors: 2.5;Monocyte progenitors: 3.5;Parietal cells: 1.8;Tuft cells: 11.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 8.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA042570, HPA050968, HPA064058" Approved Supported Nucleoplasm NA NA 58000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 40 Nucleoplasm "HPA042570: , HPA050968: , HPA064058: " "unprognostic (8.65e-2)" "unprognostic (2.11e-1)" "unprognostic (4.60e-2)" "unprognostic (2.22e-1)" "unprognostic (3.53e-2)" "unprognostic (2.44e-1)" "unprognostic (7.09e-2)" "unprognostic (2.79e-3)" "unprognostic (1.38e-2)" "unprognostic (7.10e-2)" "unprognostic (7.82e-2)" "unprognostic (1.67e-3)" "unprognostic (2.49e-1)" "unprognostic (1.51e-2)" H3C14 "H3, H3.2, H3/m, H3F2, H3FM, HIST2H3C, MGC9629" ENSG00000203811 "H3 clustered histone 14" Q71DI3 1 149840687-149841208 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 1.4;brain: 2.3;prostate: 1.7;retina: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042570, HPA050968, HPA064058, CAB069990" Supported Supported Nucleoplasm NA NA 58000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 27: Cerebellum - Synaptic function" "Cluster 15: Non-specific - Transcription" "Cluster 41: Non-specific - Nucleosome assembly" 59 Nucleoplasm "CAB069990: , HPA042570: , HPA050968: , HPA064058: " "unprognostic (2.90e-2)" "unprognostic (1.04e-1)" "unprognostic (6.99e-2)" "unprognostic (2.74e-1)" "unprognostic (1.91e-1)" "unprognostic (1.26e-2)" "unprognostic (8.12e-2)" "unprognostic (1.84e-1)" "unprognostic (2.66e-1)" "unprognostic (7.50e-2)" "unprognostic (1.14e-3)" "unprognostic (1.48e-1)" "unprognostic (1.19e-1)" H3C15 "H3/n, H3/o, HIST2H3A" ENSG00000203852 "H3 clustered histone 15" Q71DI3 1 149852608-149853125 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 2.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 21 "medulla oblongata: 1.9;pons: 2.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "HPA042570, HPA050968, HPA064058" Approved Supported Nucleoplasm NA NA 58000000 "Cluster 64: Non-specific - Transcription" "Cluster 46: Brainstem - Mixed function" "Cluster 41: Non-specific - Nucleosome assembly" 72 Nucleoplasm "HPA042570: , HPA050968: , HPA064058: " "unprognostic (2.90e-2)" "unprognostic (1.04e-1)" "unprognostic (6.99e-2)" "unprognostic (2.74e-1)" "unprognostic (1.19e-1)" "unprognostic (1.26e-2)" "unprognostic (8.12e-2)" "unprognostic (1.84e-1)" "unprognostic (2.66e-1)" "unprognostic (7.50e-2)" "unprognostic (1.14e-3)" "unprognostic (1.48e-1)" "unprognostic (1.19e-1)" H3C2 "H3/l, H3FL, HIST1H3B" ENSG00000286522 "H3 clustered histone 2" P68431 6 26031589-26032099 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" DNA-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "bone marrow: 6.0;lymphoid tissue: 1.6" "Cell type enhanced" "Detected in some" "Erythrocyte progenitors: 360.1;Erythrocytes: 72.6;Megakaryocyte progenitors: 189.5;Monocyte progenitors: 290.2;Neutrophil progenitors: 81.0;Plasma cells: 33.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 14.5;Colon Adenocarcinoma (TCGA): 20.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "HPA042570, HPA050968, HPA064058" Approved Supported Nucleoplasm NA NA 57000000 "Cluster 16: Non-specific - Cell proliferation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 80 Nucleoplasm "HPA042570: , HPA050968: , HPA064058: " "unprognostic (3.78e-2)" "unprognostic (1.37e-1)" "unprognostic (4.86e-3)" "unprognostic (1.16e-1)" "unprognostic (3.63e-1)" "unprognostic (2.12e-1)" "unprognostic (4.87e-2)" "unprognostic (7.21e-2)" "unprognostic (5.30e-2)" "unprognostic (7.08e-2)" "unprognostic (1.85e-1)" "unprognostic (6.52e-2)" "unprognostic (3.43e-1)" "unprognostic (9.47e-2)" H3C3 "H3.1, H3/c, H3FC, HIST1H3C" ENSG00000287080 "H3 clustered histone 3" P68431 6 26045384-26045869 "Disease related genes, Predicted intracellular proteins" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.0;lymphoid tissue: 1.0" "Cell type enhanced" "Detected in some" "Erythrocyte progenitors: 61.6;Erythrocytes: 15.2;Megakaryocyte progenitors: 36.7;Monocyte progenitors: 36.4;Neutrophil progenitors: 10.2;Plasma cells: 8.7;Tuft cells: 23.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "HPA042570, HPA050968, HPA064058" Approved Supported Nucleoplasm NA NA 57000000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 44: Non-specific - Mixed function" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 91 Nucleoplasm "HPA042570: , HPA050968: , HPA064058: " "unprognostic (3.97e-2)" "unprognostic (1.11e-1)" "unprognostic (1.34e-1)" "unprognostic (1.29e-2)" "unprognostic (1.87e-1)" "potential prognostic unfavorable (2.30e-4)" "unprognostic (3.15e-1)" "unprognostic (3.85e-1)" "unprognostic (7.17e-2)" H3C4 "H3/b, H3FB, HIST1H3D" ENSG00000197409 "H3 clustered histone 4" P68431 6 26196784-26197286 "Disease related genes, Essential proteins, Predicted intracellular proteins" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "bone marrow: 11.5" "Cell type enriched" "Detected in single" 7 "Microglia: 1.5" "Group enriched" "Detected in some" 4 "central nervous system macrophage: 3.4;leukocyte: 1.9" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 10.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Breast - T-cells" "Not detected" "Not detected" "HPA042570, HPA050968, HPA064058" Approved Supported Nucleoplasm NA NA 57000000 "Cluster 20: Non-specific - DNA binding" "Cluster 15: Bone marrow - Innate immune response" "Cluster 35: Non-specific - DNA binding" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 102: Non-specific - Mixed function" 68 Nucleoplasm "HPA042570: , HPA050968: , HPA064058: " "unprognostic (2.05e-3)" "unprognostic (4.64e-1)" "unprognostic (1.64e-2)" "unprognostic (1.18e-1)" "unprognostic (4.09e-1)" "unprognostic (5.69e-2)" "unprognostic (3.34e-1)" "unprognostic (7.18e-3)" "unprognostic (9.33e-3)" "unprognostic (2.56e-1)" "potential prognostic favorable (1.27e-4)" "unprognostic (1.26e-2)" "unprognostic (1.39e-1)" "unprognostic (2.80e-2)" "unprognostic (1.81e-2)" "unprognostic (1.93e-2)" "unprognostic (4.62e-1)" "unprognostic (5.77e-2)" H3C6 "H3.1, H3/d, H3FD, HIST1H3E" ENSG00000274750 "H3 clustered histone 6" P68431 6 26224199-26227473 "Disease related genes, Predicted intracellular proteins" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast lactating cells: 10.5;Cardiomyocytes: 11.1;Epididymal principal cells: 10.2;Esophageal apical cells: 21.1;Gastric progenitor cells: 14.1;Thymic myoid cells: 9.5" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 2.8;choroid plexus epithelial cell: 2.3;leukocyte: 2.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Prostate - Prostate glandular cells" "HPA042570, HPA050968, HPA064058" Approved Supported Nucleoplasm NA NA 57000000 "Cluster 13: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cellular respiration" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 84: Apical squamous epithelium - Cornification" 123 Nucleoplasm "HPA042570: , HPA050968: , HPA064058: " "unprognostic (2.25e-1)" "unprognostic (8.11e-2)" "unprognostic (3.25e-1)" "unprognostic (5.21e-2)" "unprognostic (4.39e-2)" "unprognostic (9.25e-2)" "unprognostic (1.34e-1)" "unprognostic (4.58e-2)" "unprognostic (3.39e-1)" "unprognostic (8.46e-2)" "unprognostic (1.64e-2)" "unprognostic (4.49e-2)" "unprognostic (1.67e-1)" "potential prognostic favorable (8.89e-4)" "unprognostic (9.61e-2)" "unprognostic (4.27e-2)" "unprognostic (4.77e-2)" "unprognostic (1.47e-1)" "unprognostic (4.11e-2)" "unprognostic (2.19e-2)" "unprognostic (9.32e-2)" "unprognostic (1.79e-1)" "unprognostic (1.46e-1)" "unprognostic (1.06e-1)" "unprognostic (3.17e-1)" "unprognostic (1.33e-2)" H3C7 "H3/i, H3FI, HIST1H3F" ENSG00000277775 "H3 clustered histone 7" P68431 6 26250142-26250635 "Disease related genes, Predicted intracellular proteins" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "bone marrow: 1.5" "Group enriched" "Detected in some" 6 "Erythrocyte progenitors: 98.9;Megakaryocyte progenitors: 54.4;Monocyte progenitors: 55.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 8.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "memory B-cell: 1.8" "Lineage enriched" "Detected in single" 5 "B-cells: 1.8" "Low cancer specificity" "Detected in some" "HPA042570, HPA050968, HPA064058, CAB070190" Approved Supported Nucleoplasm NA NA 57000000 "Cluster 16: Non-specific - Cell proliferation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 6: Non-specific - Immune response" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 74 Nucleoplasm "CAB070190: , HPA042570: , HPA050968: , HPA064058: " "unprognostic (1.89e-2)" "unprognostic (2.29e-1)" "unprognostic (3.31e-1)" "unprognostic (9.04e-2)" "unprognostic (1.21e-2)" "unprognostic (4.00e-2)" "unprognostic (2.15e-2)" "potential prognostic favorable (9.48e-4)" "unprognostic (6.29e-3)" H3C8 "H3/h, H3FH, HIST1H3G" ENSG00000273983 "H3 clustered histone 8" P68431 6 26270918-26271413 "Disease related genes, Essential proteins, Predicted intracellular proteins" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 2.2;lymphoid tissue: 2.0" "Group enriched" "Detected in some" 4 "Erythrocyte progenitors: 91.3;Megakaryocyte progenitors: 62.6;Monocyte progenitors: 71.7" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "memory CD4 T-cell: 1.2;T-reg: 1.2" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "cervical cancer: 15.0" "Low region specificity" "Detected in all" "HPA042570, HPA050968, HPA064058" Approved Supported Nucleoplasm NA NA 57000000 "Cluster 16: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 12: Non-specific - Vasculature" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 72 Nucleoplasm "HPA042570: , HPA050968: , HPA064058: " "unprognostic (2.52e-2)" "unprognostic (4.95e-3)" "unprognostic (4.19e-2)" "unprognostic (3.49e-1)" "unprognostic (7.82e-2)" "unprognostic (5.89e-2)" "unprognostic (2.84e-1)" "unprognostic (1.98e-1)" H3Y1 "H3.Y, H3.Y.1" ENSG00000269466 "H3.Y histone 1" P0DPK2 5 17654868-17655849 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Early spermatids: 4.9;Epididymal principal cells: 2.1;Late spermatids: 3.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bladder Urothelial Carcinoma (TCGA): 1.2;Testicular Germ Cell Tumor (TCGA): 1.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "breast cancer: 1.0" "HPA042570, HPA064058" Uncertain Supported Nucleoplasm NA NA "Cluster 27: Breast cancer - Unknown function" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" Nucleoplasm "HPA042570: , HPA064058: " "unprognostic (1.17e-1)" H3Y2 "H3.X, H3.Y.2" ENSG00000268799 "H3.Y histone 2" P0DPK5 5 17490967-17492076 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Early spermatids: 9.6;Late spermatids: 3.3;Undifferentiated spermatogonia: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA042570, HPA064058" Approved Supported Nucleoplasm NA NA "Cluster 27: Breast cancer - Unknown function" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" Nucleoplasm "HPA042570: , HPA064058: " H4C1 "H4FA, HIST1H4A" ENSG00000278637 "H4 clustered histone 1" P62805 6 26021649-26022050 "Disease related genes, Predicted intracellular proteins" DNA-binding "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 1.6;lymphoid tissue: 3.2" "Cell type enhanced" "Detected in some" "Erythrocyte progenitors: 39.2;Hematopoietic stem cells: 12.6;Megakaryocyte progenitors: 17.3;Megakaryocyte-Erythroid progenitors: 6.7;Monocyte progenitors: 17.2;pDCs: 6.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Colon Adenocarcinoma (TCGA): 3.1;Uterine Corpus Endometrial Carcinoma (TCGA): 3.2" "Region enhanced" "Detected in all" "cerebellum: 54.9" "Group enriched" "Detected in some" 6 "eosinophil: 2.9;neutrophil: 10.5" "Lineage enriched" "Detected in many" 9 "granulocytes: 10.5" "Low cancer specificity" "Detected in many" "CAB021887, HPA042201" Supported NA NA 97000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 2: Neurons - Nucleosome" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 449 "CAB021887: , HPA042201: " "unprognostic (1.60e-2)" "unprognostic (1.07e-1)" "unprognostic (1.28e-1)" "unprognostic (3.91e-2)" "unprognostic (6.33e-3)" "unprognostic (1.35e-1)" "unprognostic (9.25e-3)" H4C11 "H4/e, H4F2iv, H4FE, HIST1H4J" ENSG00000197238 "H4 clustered histone 11" P62805 6 27824092-27824480 "Disease related genes, Predicted intracellular proteins" DNA-binding "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 17.6" "Cell type enhanced" "Detected in some" "Colonocytes: 18.4;Enteric stem cells: 7.7;Enteric transient amplifying cells: 6.4;Enterocytes: 11.2;Extravillous trophoblasts: 6.4;Goblet cells: 10.5;Megakaryocytes: 6.2;Neuroendocrine cells: 20.9;Paneth cells: 7.7;Parietal cells: 7.1;Tuft cells: 23.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 6 "basophil: 81.5" "Lineage enriched" "Detected in all" 6 "granulocytes: 81.5" "Cancer enhanced" "Detected in some" "colorectal cancer: 1.3;lymphoma: 1.8" "Low region specificity" "Detected in some" HPA042201 Supported NA NA 97000000 "Cluster 70: Non-specific - Protein processing" "Cluster 23: Choroid plexus - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" 62 "HPA042201: " "unprognostic (6.26e-1)" "unprognostic (3.90e-1)" "unprognostic (1.00e-2)" "unprognostic (2.93e-1)" "unprognostic (6.88e-3)" "unprognostic (8.00e-2)" "unprognostic (6.54e-2)" "unprognostic (6.79e-1)" "unprognostic (1.84e-1)" H4C12 "dJ160A22.1, H4/d, H4F2iii, H4FD, HIST1H4K" ENSG00000273542 "H4 clustered histone 12" P62805 6 27831174-27831560 "Disease related genes, Predicted intracellular proteins" DNA-binding "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.9" "Cell type enhanced" "Detected in some" "Erythrocyte progenitors: 2.6;Megakaryocyte progenitors: 1.1;Platelets: 2.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 161.4" "Lineage enriched" "Detected in all" 4 "granulocytes: 161.4" "Low cancer specificity" "Detected in all" HPA042201 Supported NA NA 97000000 "Cluster 32: Basophils - Transcription" "Cluster 15: Bone marrow - Innate immune response" "Cluster 14: Neurons - Synaptic function" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 64 "HPA042201: " "potential prognostic unfavorable (4.80e-4)" "unprognostic (6.37e-2)" "potential prognostic favorable (6.77e-4)" "unprognostic (1.75e-1)" "unprognostic (1.67e-1)" "unprognostic (2.44e-1)" "unprognostic (6.54e-3)" "unprognostic (6.17e-2)" "unprognostic (3.04e-2)" "unprognostic (1.46e-1)" "unprognostic (1.23e-1)" "unprognostic (3.27e-1)" "unprognostic (1.45e-1)" "unprognostic (2.76e-2)" "unprognostic (2.48e-2)" "unprognostic (8.44e-2)" "unprognostic (3.38e-2)" "unprognostic (2.57e-1)" "unprognostic (3.72e-2)" "unprognostic (9.16e-2)" "unprognostic (1.69e-1)" "unprognostic (7.46e-2)" "unprognostic (1.45e-1)" "unprognostic (2.15e-1)" "unprognostic (2.20e-1)" "unprognostic (8.36e-2)" H4C13 "H4.k, H4/k, H4FK, HIST1H4L" ENSG00000275126 "H4 clustered histone 13" P62805 6 27873148-27873534 "Disease related genes, Predicted intracellular proteins" DNA-binding "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Erythrocyte progenitors: 16.2;Megakaryocyte progenitors: 8.0;Monocyte progenitors: 7.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Colon Adenocarcinoma (TCGA): 3.8;Uterine Corpus Endometrial Carcinoma (TCGA): 2.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 2.7" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" HPA042201 Approved NA NA 97000000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 66 "HPA042201: " "unprognostic (2.45e-2)" "unprognostic (2.45e-1)" "unprognostic (4.96e-1)" "unprognostic (5.44e-2)" H4C14 "H4/n, H4F2, H4FN, HIST2H4, HIST2H4A" ENSG00000270882 "H4 clustered histone 14" P62805 1 149832657-149839767 "Disease related genes, Predicted intracellular proteins" DNA-binding "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 9 "Platelets: 35.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Prostate - Prostate glandular cells" HPA042201 Approved NA NA 97000000 "Cluster 24: Non-specific - Transcription" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 47: Platelets - Hemostasis" 71 "HPA042201: " "unprognostic (2.20e-2)" "unprognostic (4.87e-2)" "unprognostic (4.85e-2)" "unprognostic (1.21e-2)" "unprognostic (3.49e-1)" "unprognostic (1.22e-1)" "unprognostic (1.56e-1)" "unprognostic (1.48e-1)" "potential prognostic favorable (1.11e-7)" "unprognostic (3.41e-2)" "unprognostic (1.79e-1)" "unprognostic (1.34e-1)" "unprognostic (1.25e-1)" "unprognostic (2.26e-1)" "unprognostic (2.79e-2)" "unprognostic (1.42e-1)" "unprognostic (6.66e-2)" "unprognostic (8.61e-2)" "unprognostic (9.29e-2)" "unprognostic (2.95e-1)" "unprognostic (4.96e-3)" "unprognostic (9.46e-2)" "unprognostic (1.65e-1)" "unprognostic (7.12e-2)" "unprognostic (3.26e-2)" "unprognostic (8.17e-2)" H4C15 "H4/o, HIST2H4B" ENSG00000270276 "H4 clustered histone 15" P62805 1 149854045-149861159 "Disease related genes, Predicted intracellular proteins" DNA-binding "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" HPA042201 Supported NA Yes 97000000 "Cluster 24: Non-specific - Transcription" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 65: Non-specific - Cell growth & division" 62 "HPA042201: " "unprognostic (1.42e-1)" "unprognostic (8.65e-2)" "unprognostic (1.26e-3)" "unprognostic (9.60e-2)" "unprognostic (4.47e-2)" "unprognostic (2.47e-1)" "unprognostic (3.35e-1)" "unprognostic (4.90e-2)" "potential prognostic favorable (2.18e-9)" "unprognostic (6.49e-3)" "unprognostic (5.55e-2)" "unprognostic (1.70e-1)" "unprognostic (9.05e-3)" "unprognostic (2.17e-2)" "unprognostic (4.00e-2)" "potential prognostic favorable (4.66e-5)" "unprognostic (3.04e-1)" "unprognostic (3.73e-2)" "unprognostic (2.82e-1)" "unprognostic (2.75e-1)" "unprognostic (6.57e-2)" "unprognostic (8.57e-2)" "unprognostic (8.36e-2)" "unprognostic (3.14e-1)" "unprognostic (1.79e-1)" H4C16 "H4-16, HIST4H4, MGC24116" ENSG00000197837 "H4 histone 16" P62805 12 14767999-14771131 "Disease related genes, Predicted intracellular proteins" DNA-binding "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Enterocytes: 21.8;Esophageal apical cells: 18.8;Plasma cells: 19.2;Tuft cells: 69.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 20.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "CAB011503, CAB037279, HPA042201" Supported Supported Nucleoplasm NA NA 97000000 "Cluster 18: Non-specific - Translation" "Cluster 82: Salivary gland - Secretion" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 65: Non-specific - Cell growth & division" 109 Nucleoplasm "CAB011503: , CAB037279: , HPA042201: " "unprognostic (1.60e-1)" "unprognostic (2.82e-1)" "unprognostic (2.91e-3)" "unprognostic (2.55e-2)" "potential prognostic unfavorable (2.38e-5)" "unprognostic (9.06e-3)" "unprognostic (1.75e-1)" "unprognostic (2.75e-1)" "unprognostic (1.91e-1)" "unprognostic (1.25e-2)" "unprognostic (3.17e-2)" "unprognostic (1.32e-1)" "unprognostic (5.27e-2)" "unprognostic (1.37e-2)" "unprognostic (5.61e-2)" "unprognostic (3.04e-3)" "unprognostic (4.83e-2)" "unprognostic (6.60e-3)" "unprognostic (3.55e-2)" H4C2 "H4/I, H4FI, HIST1H4B" ENSG00000278705 "H4 clustered histone 2" P62805 6 26026896-26027283 "Disease related genes, Predicted intracellular proteins" DNA-binding "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 2.2;choroid plexus: 2.3;lymphoid tissue: 2.2" "Cell type enhanced" "Detected in some" "Breast lactating cells: 14.4;Erythrocyte progenitors: 26.3;Erythrocytes: 5.9;Foveolar cells: 7.6;Hematopoietic stem cells: 7.3;Megakaryocyte progenitors: 8.4;Monocyte progenitors: 11.8;Mucous neck cells: 6.3;Tuft cells: 11.5" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Bladder Urothelial Carcinoma (TCGA): 6.4;Colon Adenocarcinoma (TCGA): 12.0;Lung Adenocarcinoma (TCGA): 3.0;Uterine Corpus Endometrial Carcinoma (TCGA): 3.6" "Region enhanced" "Detected in all" "cerebellum: 247.2" "Immune cell enriched" "Detected in many" 6 "neutrophil: 47.3" "Lineage enriched" "Detected in many" 6 "granulocytes: 47.3" "Low cancer specificity" "Detected in some" HPA042201 Supported NA NA 97000000 "Cluster 20: Non-specific - DNA binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 35: Non-specific - DNA binding" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 65 "HPA042201: " "unprognostic (1.41e-1)" "unprognostic (1.85e-1)" "unprognostic (4.42e-1)" "unprognostic (2.69e-1)" "unprognostic (2.14e-2)" "unprognostic (7.23e-2)" "unprognostic (1.88e-1)" "unprognostic (1.42e-1)" "unprognostic (2.61e-1)" H4C3 "dJ221C16.1, H4/g, H4FG, HIST1H4C" ENSG00000197061 "H4 clustered histone 3" P62805 6 26103933-26104337 "Disease related genes, Predicted intracellular proteins" DNA-binding "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.7;lymphoid tissue: 3.4" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 1788.2;Early primary spermatocytes: 3643.3;Erythrocyte progenitors: 4335.0;Megakaryocyte progenitors: 2064.6;Monocyte progenitors: 2139.6" "Cell type enhanced" "Detected in all" "upper rhombic lip: 72.4" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 35.6;Ovary Serous Cystadenocarcinoma (TCGA): 24.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" HPA042201 Supported NA Yes 97000000 "Cluster 20: Non-specific - DNA binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 35: Non-specific - DNA binding" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 69 "HPA042201: " "unprognostic (2.99e-2)" "unprognostic (7.38e-2)" "unprognostic (2.45e-1)" "unprognostic (2.85e-2)" "unprognostic (1.61e-1)" "unprognostic (2.77e-1)" "unprognostic (2.03e-3)" "unprognostic (1.74e-1)" "unprognostic (7.69e-2)" "unprognostic (2.51e-2)" "unprognostic (7.44e-2)" "unprognostic (9.40e-2)" "unprognostic (1.76e-2)" "unprognostic (3.11e-1)" "unprognostic (2.62e-3)" H4C4 "H4/b, H4FB, HIST1H4D" ENSG00000277157 "H4 clustered histone 4" P62805 6 26188710-26189112 "Disease related genes, Predicted intracellular proteins" DNA-binding "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 1.9" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 68.7;Erythrocytes: 17.8;Megakaryocyte progenitors: 34.6;Megakaryocytes: 12.4;Monocyte progenitors: 32.6;Tuft cells: 23.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 26.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "naive B-cell: 3.5" "Lineage enriched" "Detected in single" 4 "B-cells: 3.5" "Low cancer specificity" "Detected in many" HPA042201 Supported NA NA 97000000 "Cluster 34: B-cells - Unknown function" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 31: Non-specific - Transcription" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 62 "HPA042201: " "unprognostic (3.67e-2)" "unprognostic (2.84e-1)" "unprognostic (5.96e-2)" "unprognostic (4.09e-2)" "unprognostic (2.60e-3)" "unprognostic (4.37e-3)" "unprognostic (3.79e-2)" "unprognostic (2.59e-2)" "unprognostic (1.93e-1)" "unprognostic (1.55e-1)" "unprognostic (4.29e-1)" "unprognostic (6.56e-2)" H4C5 "H4/j, H4FJ, HIST1H4E" ENSG00000276966 "H4 clustered histone 5" P62805 6 26204610-26205021 "Disease related genes, Predicted intracellular proteins" DNA-binding "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 125.5;Erythrocytes: 31.4;Hematopoietic stem cells: 36.9;Megakaryocyte progenitors: 48.2;Megakaryocyte-Erythroid progenitors: 39.5;Monocyte progenitors: 73.7;Tuft cells: 34.6" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 5.7;oligodendrocyte: 4.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Breast - T-cells" HPA042201 Supported NA NA 97000000 "Cluster 24: Non-specific - Transcription" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 61 "HPA042201: " "unprognostic (6.70e-2)" "unprognostic (9.35e-2)" "unprognostic (2.72e-3)" "unprognostic (3.56e-2)" "unprognostic (1.95e-1)" "unprognostic (1.93e-1)" "potential prognostic unfavorable (4.02e-4)" "unprognostic (1.59e-2)" "unprognostic (2.19e-1)" "unprognostic (4.22e-2)" "unprognostic (7.46e-3)" "unprognostic (7.92e-2)" "unprognostic (7.25e-2)" "unprognostic (4.97e-2)" "unprognostic (1.28e-1)" "unprognostic (5.08e-2)" H4C6 "H4, H4/c, H4FC, HIST1H4F" ENSG00000274618 "H4 clustered histone 6" P62805 6 26240393-26240793 "Disease related genes, Predicted intracellular proteins" DNA-binding "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Early primary spermatocytes: 4.8;Erythrocyte progenitors: 48.4;Erythrocytes: 7.4;Megakaryocyte progenitors: 13.4;Megakaryocyte-Erythroid progenitors: 5.4;Monocyte progenitors: 17.0;Neutrophil progenitors: 5.3;Plasma cells: 5.2;Thymocytes: 9.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Lung Adenocarcinoma (TCGA): 2.1;Ovary Serous Cystadenocarcinoma (TCGA): 1.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in single" "lymphoma: 1.1" HPA042201 Supported NA NA 97000000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 53: Neurons - Mixed function" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 69 "HPA042201: " "unprognostic (1.90e-1)" "unprognostic (1.89e-1)" "unprognostic (4.40e-2)" H4C7 "H4/l, H4FL, HIST1H4G" ENSG00000275663 "H4 clustered histone 7" Q99525 6 26246611-26246996 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA042201 Supported NA NA 10 "HPA042201: " H4C8 "H4/h, H4FH, HIST1H4H" ENSG00000158406 "H4 clustered histone 8" P62805 6 26277609-26285638 "Disease related genes, Predicted intracellular proteins" DNA-binding "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 2.0;skeletal muscle: 2.2" "Cell type enhanced" "Detected in many" "Breast lactating cells: 97.3;Erythrocyte progenitors: 62.5;Esophageal apical cells: 89.4;Gastric progenitor cells: 62.8;Monocyte progenitors: 58.4;Oocytes: 59.9;Plasma cells: 54.7;Platelets: 190.2;Prostatic club cells: 63.4" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 14.2" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 13.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "eosinophil: 5.1;neutrophil: 12.2" "Lineage enriched" "Detected in many" 10 "granulocytes: 12.2" "Low cancer specificity" "Detected in many" "Breast - T-cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" HPA042201 Supported NA NA 97000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - DNA binding" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 65: Non-specific - Cell growth & division" 62 "HPA042201: " "unprognostic (1.36e-1)" "unprognostic (1.35e-1)" "unprognostic (1.22e-1)" "unprognostic (1.73e-1)" "unprognostic (1.03e-1)" "unprognostic (8.43e-2)" "unprognostic (8.99e-1)" "unprognostic (1.47e-2)" "unprognostic (1.73e-1)" "unprognostic (5.33e-1)" "unprognostic (6.86e-2)" "unprognostic (4.25e-1)" "unprognostic (2.73e-1)" H4C9 "H4/m, H4FM, HIST1H4I" ENSG00000276180 "H4 clustered histone 9" P62805 6 27139282-27139678 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" DNA-binding "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 3.9" "Cell type enhanced" "Detected in some" "Erythrocyte progenitors: 25.5;Erythrocytes: 8.9;Megakaryocyte progenitors: 13.2;Megakaryocyte-Erythroid progenitors: 2.8;Monocyte progenitors: 22.5;Neutrophil progenitors: 5.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Myeloma: 12.5" HPA042201 Approved NA NA 97000000 "Cluster 14: Non-specific - Unknown function" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 83 "HPA042201: " "unprognostic (2.60e-1)" "unprognostic (1.24e-1)" "unprognostic (4.13e-2)" "unprognostic (2.48e-2)" "unprognostic (1.58e-2)" "unprognostic (1.83e-1)" "unprognostic (9.75e-2)" "unprognostic (6.34e-2)" "unprognostic (5.80e-2)" "unprognostic (2.37e-1)" "unprognostic (1.40e-1)" "unprognostic (3.22e-1)" "potential prognostic unfavorable (2.84e-4)" "unprognostic (6.67e-2)" "unprognostic (2.37e-2)" "unprognostic (1.63e-3)" "potential prognostic favorable (1.11e-4)" "unprognostic (1.53e-3)" "unprognostic (3.07e-2)" "unprognostic (5.03e-2)" "unprognostic (1.01e-3)" "unprognostic (2.30e-2)" "unprognostic (5.22e-2)" "unprognostic (2.61e-1)" "unprognostic (2.18e-1)" "unprognostic (3.71e-1)" H6PD "GDH, H6PDH" ENSG00000049239 "Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase" O95479 1 9234774-9271337 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" "Hydrolase, Multifunctional enzyme, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 89.4" "Cell type enhanced" "Detected in many" "Hepatocytes: 194.5;Myonuclei: 140.0;Salivary acinar cells: 131.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004824, HPA005440" Approved Uncertain Cytosol "Intracellular and membrane" Enzyme NA NA 74000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 12 Cytosol "HPA004824: , HPA005440: " "unprognostic (1.10e-2)" "unprognostic (1.70e-2)" "unprognostic (4.43e-3)" "unprognostic (5.81e-3)" "unprognostic (1.47e-1)" "unprognostic (2.28e-1)" "unprognostic (1.92e-2)" "unprognostic (3.45e-3)" "unprognostic (5.22e-2)" "unprognostic (2.18e-1)" "potential prognostic favorable (1.80e-4)" "unprognostic (4.21e-3)" "unprognostic (6.86e-2)" "unprognostic (1.63e-1)" "unprognostic (9.71e-2)" "unprognostic (1.14e-1)" "unprognostic (1.85e-1)" "unprognostic (7.85e-2)" "unprognostic (2.31e-1)" "unprognostic (1.91e-3)" "unprognostic (2.57e-1)" "unprognostic (1.17e-2)" "unprognostic (3.77e-1)" "unprognostic (2.39e-2)" "unprognostic (1.24e-1)" "unprognostic (7.66e-2)" "unprognostic (2.16e-1)" "unprognostic (1.95e-1)" "unprognostic (1.34e-1)" "unprognostic (3.68e-2)" "unprognostic (2.89e-2)" HAAO ENSG00000162882 "3-hydroxyanthranilate 3,4-dioxygenase" P46952 2 42767089-42792593 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Dioxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "liver: 276.6" "Group enriched" "Detected in many" 4 "Enterocytes: 262.9;Hepatocytes: 295.5" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 49.4" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 111.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 23.2" "Group enriched" "Detected in many" 5 "dendritic cells: 23.2;granulocytes: 19.2;monocytes: 17.4" "Cancer enhanced" "Detected in many" "colorectal cancer: 12.5;liver cancer: 10.0" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA036394, HPA042024" Enhanced NA NA 1400000 "Cluster 29: Non-specific - Unknown function" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 39: Astrocytes - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 1: Enterocytes - Absorption and Digestion" 2 "HPA036394: , HPA042024: " "unprognostic (1.54e-1)" "unprognostic (1.64e-2)" "unprognostic (2.08e-2)" "unprognostic (1.71e-2)" "unprognostic (1.51e-1)" "unprognostic (5.46e-2)" "unprognostic (3.87e-1)" "unprognostic (2.22e-1)" "unprognostic (8.83e-2)" "unprognostic (3.33e-2)" "potential prognostic favorable (2.60e-9)" "unprognostic (2.58e-3)" "potential prognostic favorable (5.02e-4)" "unprognostic (1.71e-3)" "unprognostic (1.75e-2)" "unprognostic (2.85e-2)" "unprognostic (1.32e-1)" "unprognostic (3.05e-1)" "unprognostic (7.55e-2)" "unprognostic (6.98e-2)" "unprognostic (3.96e-2)" "unprognostic (1.34e-1)" "unprognostic (2.46e-1)" "unprognostic (4.15e-2)" "unprognostic (5.63e-3)" "unprognostic (9.35e-2)" "unprognostic (8.95e-2)" "unprognostic (2.21e-2)" "unprognostic (5.40e-2)" "unprognostic (1.25e-1)" "unprognostic (2.78e-1)" HABP2 "FSAP, HABP, HGFAL, PHBP" ENSG00000148702 "Hyaluronan binding protein 2" Q14520 10 113550837-113589602 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "liver: 408.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 81.1;Cholangiocytes: 119.7;Endometrial ciliated cells: 23.8;Gastric chief cells: 27.3;Hepatocytes: 246.8;Mucous neck cells: 20.8;Oocytes: 82.9;Pancreatic duct cells: 42.8" "Cell type enhanced" "Detected in some" "deep-layer near-projecting: 1.1;miscellaneous: 1.7;upper-layer intratelencephalic: 2.1" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 150.7" "Region enhanced" "Detected in some" "cerebral cortex: 2.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Kidney cancer: 14.7;liver cancer: 19.4" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Stomach - Mitotic cells (Stomach)" "Not detected" "Not detected" "Not detected" "Not detected" HPA019518 Uncertain "Secreted to blood" Enzyme NA NA 20200000000 8100000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 53: Neurons - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" "HPA019518: " "unprognostic (2.45e-2)" "unprognostic (6.74e-2)" "unprognostic (2.82e-1)" "unprognostic (8.02e-3)" "unprognostic (1.05e-2)" "unprognostic (4.07e-2)" "unprognostic (1.30e-1)" "unprognostic (2.82e-1)" "unprognostic (2.19e-2)" "unprognostic (1.05e-1)" "unprognostic (2.99e-3)" "potential prognostic favorable (7.25e-8)" "unprognostic (3.93e-1)" "unprognostic (3.82e-2)" "unprognostic (3.13e-2)" "unprognostic (6.48e-2)" "unprognostic (5.36e-2)" "unprognostic (1.33e-1)" "unprognostic (1.10e-3)" "unprognostic (1.27e-3)" "unprognostic (2.64e-1)" "unprognostic (1.95e-1)" HABP4 "IHABP4, SERBP1L" ENSG00000130956 "Hyaluronan binding protein 4" Q5JVS0 9 96450169-96491336 "Predicted intracellular proteins" "mRNA processing, mRNA splicing, Transcription, Transcription regulation, Translation regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 109.9" "Cell type enriched" "Detected in many" 4 "Late spermatids: 1345.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 1.9;T-cells: 1.6" "Low cancer specificity" "Detected in all" "Lung - Smooth muscle cells, Minor Salivary Gland - Endothelial cells, Testis - Late spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055969, HPA062366" Enhanced Supported "Nuclear membrane,Cytosol" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 78: Brain - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 19 "Nuclear membrane" Cytosol "HPA055969: , HPA062366: " "unprognostic (7.52e-2)" "unprognostic (8.02e-2)" "unprognostic (1.20e-1)" "unprognostic (3.18e-1)" "unprognostic (4.54e-2)" "unprognostic (2.56e-2)" "unprognostic (1.35e-1)" "unprognostic (3.72e-3)" "unprognostic (2.00e-1)" "unprognostic (2.52e-1)" "validated prognostic favorable (1.41e-9)" "validated prognostic favorable (1.49e-5)" "unprognostic (1.88e-3)" "unprognostic (7.38e-3)" "unprognostic (1.25e-3)" "unprognostic (7.16e-2)" "unprognostic (2.99e-1)" "unprognostic (2.22e-2)" "unprognostic (1.85e-1)" "unprognostic (4.85e-3)" "unprognostic (3.57e-2)" "unprognostic (8.23e-3)" "unprognostic (3.10e-1)" "unprognostic (2.35e-1)" "unprognostic (3.45e-3)" "unprognostic (3.91e-3)" "unprognostic (2.45e-1)" "unprognostic (3.45e-1)" "unprognostic (2.89e-2)" "unprognostic (3.39e-2)" "unprognostic (1.18e-1)" HACD1 "CAP, PTPLA" ENSG00000165996 "3-hydroxyacyl-CoA dehydratase 1" B0YJ81 10 17589032-17617374 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Developmental protein, Lyase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 68.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 157.4;Alveolar cells type 2: 83.7;Cardiomyocytes: 115.5;Gonadotrophs: 141.6;Megakaryocyte progenitors: 85.9;Megakaryocyte-Erythroid progenitors: 85.3;Melanocytes: 147.7;Myonuclei: 207.3;Parietal cells: 111.4;Smooth muscle cells: 102.4;Thymic myoid cells: 95.2;Vascular smooth muscle cells: 100.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 11 "T-reg: 55.9" "Lineage enriched" "Detected in many" 12 "T-cells: 55.9" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Colon - Smooth muscle cells, Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 35: Non-specific - Mixed function" "Cluster 25: Non-specific - Transcription" "Cluster 72: Neuronal - Signal transduction" "Cluster 62: Smooth muscle cells - Muscle contraction" 4 "unprognostic (1.70e-2)" "unprognostic (8.57e-3)" "unprognostic (4.71e-2)" "unprognostic (2.91e-1)" "unprognostic (1.75e-2)" "unprognostic (2.29e-1)" "potential prognostic favorable (1.96e-4)" "unprognostic (3.32e-3)" "unprognostic (5.13e-2)" "potential prognostic unfavorable (1.57e-4)" "unprognostic (2.02e-2)" "unprognostic (1.13e-1)" "unprognostic (1.73e-2)" "unprognostic (1.39e-3)" "unprognostic (9.56e-2)" "unprognostic (8.73e-2)" "unprognostic (2.47e-1)" "unprognostic (1.08e-2)" "unprognostic (1.36e-1)" "unprognostic (2.08e-1)" "unprognostic (1.03e-2)" "unprognostic (4.81e-2)" "unprognostic (6.82e-2)" "unprognostic (9.78e-2)" "unprognostic (5.58e-2)" "unprognostic (1.87e-2)" "unprognostic (7.55e-2)" "unprognostic (2.50e-1)" "unprognostic (4.97e-2)" HACD2 PTPLB ENSG00000206527 "3-hydroxyacyl-CoA dehydratase 2" Q6Y1H2 3 123490820-123585053 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 328.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB019282 Approved NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 89: Adipocytes - Lipid metabolism" 12 "CAB019282: " "unprognostic (3.68e-2)" "unprognostic (3.65e-2)" "unprognostic (1.00e-2)" "unprognostic (3.37e-1)" "unprognostic (1.07e-1)" "unprognostic (1.02e-1)" "potential prognostic unfavorable (6.12e-4)" "unprognostic (4.07e-2)" "unprognostic (1.87e-3)" "potential prognostic favorable (1.30e-5)" "unprognostic (1.02e-2)" "unprognostic (1.17e-1)" "unprognostic (8.34e-3)" "unprognostic (3.79e-2)" "unprognostic (1.19e-2)" "unprognostic (5.37e-2)" "unprognostic (1.76e-2)" "unprognostic (6.57e-2)" "unprognostic (5.42e-3)" "potential prognostic unfavorable (9.83e-5)" "unprognostic (1.55e-3)" "unprognostic (3.10e-2)" "unprognostic (1.96e-1)" "unprognostic (1.28e-2)" "unprognostic (1.55e-1)" "unprognostic (5.88e-2)" "unprognostic (2.83e-1)" "unprognostic (6.85e-3)" "unprognostic (1.81e-1)" HACD3 "B-ind1, HSPC121, PTPLAD1" ENSG00000074696 "3-hydroxyacyl-CoA dehydratase 3" Q9P035 15 65530418-65578349 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014837, HPA060347" Enhanced Enhanced "Endoplasmic reticulum" NA NA 28000 "Cluster 24: Non-specific - Transcription" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 58: Non-specific - Nuclear processes" "Cluster 69: Urothelial cells - Basic cellular functions" 32 "Endoplasmic reticulum" "HPA014837: , HPA060347: " "unprognostic (2.09e-1)" "unprognostic (1.10e-2)" "unprognostic (2.19e-1)" "unprognostic (9.77e-2)" "unprognostic (5.20e-2)" "unprognostic (4.58e-1)" "unprognostic (1.46e-1)" "unprognostic (9.83e-2)" "unprognostic (7.40e-2)" "potential prognostic favorable (7.02e-6)" "unprognostic (7.10e-2)" "unprognostic (1.60e-1)" "unprognostic (1.64e-1)" "unprognostic (1.75e-2)" "unprognostic (2.25e-1)" "unprognostic (1.08e-1)" "unprognostic (2.72e-1)" "unprognostic (1.55e-1)" "unprognostic (2.93e-1)" "unprognostic (7.64e-2)" "unprognostic (3.64e-1)" "unprognostic (2.42e-1)" "unprognostic (1.03e-1)" "unprognostic (2.50e-1)" "unprognostic (1.17e-1)" "unprognostic (2.78e-1)" "unprognostic (2.78e-2)" "unprognostic (4.52e-2)" "unprognostic (6.45e-2)" HACD4 "Em:AL662879.1, PTPLAD2" ENSG00000188921 "3-hydroxyacyl-CoA dehydratase 4" Q5VWC8 9 20999509-21031640 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 11.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 95.6;cDC: 86.9;Epicardial cells: 84.1;Hofbauer cells: 101.1;Megakaryocytes: 173.1;monocytes: 78.8;Neutrophil progenitors: 103.5;Neutrophils: 139.3;Platelets: 500.0;Respiratory ciliated cells: 106.9" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 88.3;leukocyte: 50.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058666 Uncertain NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 9: Non-specific - Receptor signaling" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 1 "HPA058666: " "unprognostic (3.86e-2)" "unprognostic (9.54e-2)" "unprognostic (1.95e-1)" "unprognostic (4.06e-2)" "unprognostic (3.32e-2)" "unprognostic (2.43e-1)" "unprognostic (4.72e-2)" "unprognostic (2.31e-1)" "unprognostic (1.79e-2)" "unprognostic (2.07e-2)" "unprognostic (1.16e-1)" "unprognostic (2.89e-3)" "unprognostic (3.14e-1)" "unprognostic (2.57e-1)" "unprognostic (1.57e-2)" "unprognostic (3.70e-2)" "unprognostic (1.55e-1)" "unprognostic (2.24e-2)" "unprognostic (3.24e-1)" "unprognostic (8.02e-2)" "unprognostic (1.84e-1)" "unprognostic (2.54e-2)" "potential prognostic unfavorable (2.39e-4)" "unprognostic (3.51e-2)" "unprognostic (1.33e-1)" "unprognostic (3.00e-3)" "unprognostic (1.41e-1)" HACE1 KIAA1320 ENSG00000085382 "HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1" Q8IYU2 6 104728094-104859919 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation, Ubl conjugation pathway" Transferase "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 28.8" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 126.3;Retinal horizontal cells: 144.2;Rod photoreceptor cells: 160.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046071 Supported "Nuclear bodies,Endoplasmic reticulum" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 34: Non-specific - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 79: Photoreceptor cells - Phototransduction" 14 "Endoplasmic reticulum" "Nuclear bodies" "HPA046071: " "unprognostic (9.67e-3)" "unprognostic (2.28e-3)" "unprognostic (1.85e-1)" "unprognostic (6.14e-2)" "unprognostic (6.73e-3)" "unprognostic (2.85e-2)" "unprognostic (1.87e-1)" "unprognostic (5.06e-3)" "unprognostic (3.41e-2)" "unprognostic (3.73e-2)" "potential prognostic favorable (9.62e-8)" "unprognostic (3.71e-3)" "unprognostic (1.45e-2)" "unprognostic (9.01e-2)" "unprognostic (2.11e-1)" "unprognostic (1.95e-1)" "unprognostic (7.49e-2)" "unprognostic (2.83e-1)" "unprognostic (1.39e-1)" "unprognostic (3.90e-1)" "unprognostic (1.39e-1)" "unprognostic (4.71e-2)" "unprognostic (8.41e-2)" "unprognostic (1.12e-1)" "potential prognostic favorable (5.63e-4)" "unprognostic (1.09e-1)" "unprognostic (6.92e-2)" "unprognostic (7.40e-2)" "unprognostic (3.58e-2)" "unprognostic (4.76e-2)" HACL1 "2-HPCL, HPCL, PHYH2" ENSG00000131373 "2-hydroxyacyl-CoA lyase 1" Q9UJ83 3 15560699-15601852 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "basophil: 115.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 115.8" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Skin - Sebaceous gland cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035496, HPA035497, HPA073760" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 32: Basophils - Transcription" "Cluster 77: Intestine - Digestion" "Cluster 31: Non-specific - Transcription" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 89: Adipocytes - Lipid metabolism" 3 Vesicles Nucleoplasm "HPA035496: , HPA035497: , HPA073760: " "unprognostic (1.62e-1)" "unprognostic (6.53e-2)" "unprognostic (7.80e-2)" "unprognostic (5.85e-2)" "unprognostic (5.77e-2)" "unprognostic (4.24e-2)" "unprognostic (1.88e-1)" "unprognostic (4.08e-3)" "unprognostic (2.13e-1)" "unprognostic (4.55e-3)" "potential prognostic favorable (1.54e-4)" "unprognostic (1.11e-1)" "unprognostic (3.49e-2)" "unprognostic (4.20e-2)" "unprognostic (2.07e-1)" "unprognostic (9.81e-2)" "unprognostic (3.13e-1)" "unprognostic (3.62e-2)" "unprognostic (1.62e-1)" "unprognostic (5.37e-2)" "unprognostic (6.94e-2)" "unprognostic (3.94e-2)" "unprognostic (3.79e-1)" "unprognostic (1.80e-1)" "potential prognostic favorable (6.53e-6)" "unprognostic (3.05e-2)" "unprognostic (8.43e-3)" "unprognostic (3.31e-1)" "unprognostic (1.83e-2)" "unprognostic (1.29e-2)" "unprognostic (2.87e-2)" HADH "HADH1, HADHSC, SCHAD" ENSG00000138796 "Hydroxyacyl-CoA dehydrogenase" Q16836 4 107989714-108035241 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Differentiation, Fatty acid metabolism, Lipid metabolism, Spermatogenesis" "Oxidoreductase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 225.9;Enteric transient amplifying cells: 237.3;Enterocytes: 337.7;Hepatocytes: 314.6;Parietal cells: 251.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Skeletal myocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039588, HPA043888" Enhanced Supported Mitochondria No Yes 1100000 "Cluster 13: Non-specific - Mitochondria" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 97: Non-specific - Cellular respiration" 6 Mitochondria "HPA039588: , HPA043888: " "unprognostic (4.57e-2)" "unprognostic (2.47e-2)" "unprognostic (2.25e-2)" "unprognostic (1.86e-1)" "unprognostic (1.08e-2)" "unprognostic (3.39e-2)" "unprognostic (2.54e-1)" "unprognostic (8.13e-3)" "unprognostic (6.59e-2)" "potential prognostic unfavorable (2.02e-4)" "potential prognostic favorable (6.62e-13)" "unprognostic (2.15e-3)" "unprognostic (7.66e-3)" "unprognostic (4.79e-3)" "potential prognostic favorable (2.47e-4)" "unprognostic (1.31e-1)" "unprognostic (2.56e-2)" "unprognostic (5.67e-2)" "unprognostic (4.29e-3)" "unprognostic (8.42e-2)" "unprognostic (1.09e-1)" "unprognostic (2.92e-1)" "unprognostic (6.61e-2)" "unprognostic (3.52e-3)" "unprognostic (2.63e-3)" "unprognostic (2.00e-1)" "unprognostic (1.35e-1)" "unprognostic (5.85e-2)" "unprognostic (1.04e-1)" "unprognostic (1.07e-1)" "unprognostic (9.25e-3)" HADHA "GBP, LCEH, LCHAD, MTPA" ENSG00000084754 "Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha" P40939 2 26190635-26244672 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Lyase, Multifunctional enzyme, Oxidoreductase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 467.6" "Cell type enhanced" "Detected in all" "Enterocytes: 536.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015536, HPA056070" Approved Enhanced Mitochondria NA NA 510000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 19: Astrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 76 Mitochondria "HPA015536: , HPA056070: " "unprognostic (2.60e-2)" "unprognostic (1.82e-1)" "unprognostic (5.40e-1)" "potential prognostic favorable (1.14e-6)" "unprognostic (6.67e-2)" "unprognostic (4.27e-1)" "unprognostic (6.52e-2)" "unprognostic (1.82e-1)" "unprognostic (2.16e-1)" "unprognostic (1.39e-1)" "unprognostic (2.20e-3)" "unprognostic (2.31e-2)" "potential prognostic favorable (8.08e-5)" "potential prognostic unfavorable (5.45e-4)" "unprognostic (1.85e-2)" "unprognostic (1.04e-2)" "unprognostic (1.89e-1)" "unprognostic (1.26e-2)" "unprognostic (6.37e-2)" "unprognostic (1.74e-1)" "unprognostic (7.44e-2)" "unprognostic (1.77e-1)" "unprognostic (2.28e-1)" "unprognostic (1.86e-1)" "unprognostic (9.60e-3)" "unprognostic (2.64e-3)" "unprognostic (6.21e-2)" "unprognostic (5.85e-2)" "unprognostic (1.24e-1)" "unprognostic (1.10e-1)" "unprognostic (2.20e-3)" HADHB MTPB ENSG00000138029 "Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta" P55084 2 26243170-26290465 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 749.3;skeletal muscle: 917.1;tongue: 1024.2" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 476.8;Enterocytes: 444.6;Esophageal apical cells: 515.4;Thymic myoid cells: 499.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037539, HPA037540, HPA066099" Enhanced Supported "Mitochondria,Equatorial segment,Principal piece" No No 130000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 19: Astrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 55: Myocytes - Oxidative muscle function" 42 Mitochondria "Equatorial segment, Principal piece" "HPA037539: , HPA037540: , HPA066099: " "unprognostic (5.14e-2)" "unprognostic (2.01e-2)" "unprognostic (2.13e-1)" "unprognostic (2.89e-1)" "unprognostic (2.67e-3)" "unprognostic (2.93e-1)" "unprognostic (1.67e-1)" "unprognostic (2.38e-1)" "unprognostic (4.47e-2)" "unprognostic (9.95e-2)" "potential prognostic favorable (9.73e-12)" "unprognostic (3.45e-2)" "unprognostic (6.11e-3)" "unprognostic (9.41e-2)" "unprognostic (2.41e-1)" "unprognostic (1.38e-1)" "unprognostic (3.08e-1)" "unprognostic (1.22e-1)" "unprognostic (2.68e-2)" "unprognostic (1.60e-1)" "unprognostic (2.42e-2)" "unprognostic (3.99e-2)" "unprognostic (1.43e-1)" "unprognostic (2.12e-1)" "unprognostic (2.38e-1)" "unprognostic (5.22e-2)" "unprognostic (1.95e-1)" "unprognostic (1.85e-1)" "unprognostic (9.94e-2)" "unprognostic (2.36e-1)" "unprognostic (1.04e-1)" HAGH "GLO2, GLXII, HAGH1" ENSG00000063854 "Hydroxyacylglutathione hydrolase" Q16775 16 1795620-1827157 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 429.4;Oocytes: 280.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Smooth muscle cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043041, HPA061143" Approved NA NA 2200000 "Cluster 25: Non-specific - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 54: Non-specific - Transcription" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 5 "HPA043041: , HPA061143: " "unprognostic (2.85e-3)" "unprognostic (1.14e-1)" "unprognostic (1.53e-1)" "unprognostic (1.01e-2)" "unprognostic (2.36e-1)" "unprognostic (9.02e-2)" "unprognostic (5.09e-2)" "unprognostic (3.70e-2)" "unprognostic (9.53e-2)" "unprognostic (3.49e-2)" "potential prognostic favorable (5.16e-4)" "unprognostic (1.87e-1)" "unprognostic (1.25e-3)" "validated prognostic favorable (7.92e-6)" "validated prognostic favorable (5.82e-4)" "unprognostic (2.20e-3)" "unprognostic (1.22e-1)" "unprognostic (1.73e-1)" "unprognostic (6.54e-2)" "unprognostic (1.82e-1)" "unprognostic (2.82e-2)" "unprognostic (1.02e-2)" "unprognostic (1.74e-1)" "unprognostic (1.35e-1)" "unprognostic (2.75e-1)" "unprognostic (8.73e-2)" "unprognostic (1.89e-1)" "unprognostic (3.15e-1)" "unprognostic (4.01e-1)" "unprognostic (2.54e-2)" "unprognostic (8.51e-2)" HAGHL MGC2605 ENSG00000103253 "Hydroxyacylglutathione hydrolase like" Q6PII5 16 726936-735525 "Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.3" "Cell type enhanced" "Detected in many" "Astrocytes: 56.6;Bergmann glia: 61.3;Choroid plexus epithelial cells: 53.2;Endometrial ciliated cells: 49.1;Ependymal cells: 197.3;Epididymal efferent duct ciliated cells: 114.6;Fallopian tube ciliated cells: 87.5;Hofbauer cells: 66.8;Respiratory ciliated cells: 119.6;Retinal ganglion cells: 50.2" "Cell type enhanced" "Detected in all" "ependymal cell: 234.1" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 55.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074402 Approved NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 21: Non-specific - Metabolism" "Cluster 54: Non-specific - Transcription" "Cluster 34: Ciliated cells - Cilia assembly & function" 1 "HPA074402: " "unprognostic (2.24e-2)" "unprognostic (1.61e-1)" "unprognostic (1.69e-1)" "unprognostic (9.05e-2)" "unprognostic (1.11e-2)" "unprognostic (6.86e-2)" "unprognostic (2.38e-1)" "unprognostic (1.21e-1)" "unprognostic (1.66e-1)" "unprognostic (3.56e-1)" "unprognostic (3.53e-2)" "unprognostic (1.06e-1)" "potential prognostic favorable (6.85e-4)" "unprognostic (1.39e-2)" "unprognostic (2.27e-2)" "unprognostic (4.68e-2)" "unprognostic (3.31e-1)" "unprognostic (6.25e-2)" "unprognostic (5.26e-2)" "unprognostic (2.96e-2)" "unprognostic (4.78e-2)" "unprognostic (1.09e-1)" "unprognostic (2.11e-1)" "unprognostic (2.06e-2)" "unprognostic (1.13e-1)" "unprognostic (4.44e-3)" "unprognostic (2.11e-1)" "unprognostic (1.35e-1)" "unprognostic (1.13e-1)" HAL HIS ENSG00000084110 "Histidine ammonia-lyase" P42357 12 95972662-95996365 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Histidine metabolism" Lyase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "liver: 184.4;skin 1: 57.7" "Group enriched" "Detected in many" 5 "Hepatocytes: 174.6;Neutrophils: 340.5" "Cell type enhanced" "Detected in some" "endothelial cell: 1.6;leukocyte: 2.7" "Cancer enriched" "Detected in some" 10 "Liver Hepatocellular Carcinoma (TCGA): 40.4" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 4 "basophil: 57.0;neutrophil: 73.6" "Lineage enriched" "Detected in many" 5 "granulocytes: 73.6" "Group enriched" "Detected in some" 4 "Leukemia: 6.6;liver cancer: 3.0" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Kidney - Macrophages, Lung - Neutrophils_2, Pituitary gland - Somatotropes, Skeletal muscle - Neutrophils, Skin - Keratinocyte (granular), Spleen - Neutrophils_2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA038547, HPA038548" Enhanced Approved Cytosol NA NA 710000 "Cluster 35: Neutrophils - Protein binding" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 15: Non-specific - Transcription" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 35 Cytosol "HPA038547: , HPA038548: " "unprognostic (1.39e-1)" "unprognostic (1.64e-1)" "unprognostic (2.76e-2)" "unprognostic (1.02e-2)" "unprognostic (1.24e-2)" "unprognostic (4.59e-3)" "unprognostic (8.64e-2)" "unprognostic (1.96e-1)" "unprognostic (1.05e-3)" "unprognostic (2.80e-1)" "unprognostic (6.54e-2)" "unprognostic (7.82e-2)" HAMP "HEPC, HFE2B, LEAP-1, LEAP1" ENSG00000105697 "Hepcidin antimicrobial peptide" P81172 19 35280716-35285143 "Disease related genes, Human disease related genes, Potential drug targets, Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial, Fungicide, Hormone" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 3623.6" "Cell type enriched" "Detected in some" 20 "Hepatocytes: 3806.5" "Cell type enriched" "Detected in single" 35 "central nervous system macrophage: 28.2" "Group enriched" "Detected in all" 8 "Glioblastoma Multiforme (TCGA): 95.7;Liver Hepatocellular Carcinoma (TCGA): 226.5" "Region enhanced" "Detected in all" "medulla oblongata: 70.6" "Group enriched" "Detected in some" 7 "myeloid DC: 1.5;plasmacytoid DC: 4.7" "Lineage enriched" "Detected in single" 10 "dendritic cells: 4.7" "Cancer enriched" "Detected in some" 5 "liver cancer: 52.5" "Pancreas - Ductal cells, Pituitary gland - Macrophages" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" Hormone NA NA 1900000 14000000 "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 12: Non-specific - Vasculature" "Cluster 18: Liver cancer - Metabolism" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" "unprognostic (1.17e-1)" "unprognostic (3.34e-3)" "unprognostic (6.12e-2)" "potential prognostic favorable (1.73e-5)" "potential prognostic unfavorable (5.60e-4)" "unprognostic (4.34e-2)" "unprognostic (2.81e-1)" "unprognostic (2.11e-1)" "unprognostic (7.30e-2)" "validated prognostic unfavorable (1.05e-5)" "validated prognostic unfavorable (2.97e-5)" "unprognostic (1.25e-1)" "unprognostic (7.19e-2)" "unprognostic (3.07e-1)" "unprognostic (3.35e-1)" "unprognostic (2.41e-2)" "unprognostic (4.68e-2)" "unprognostic (3.81e-2)" "unprognostic (1.98e-1)" "unprognostic (7.28e-2)" "unprognostic (1.61e-1)" "unprognostic (2.24e-1)" "unprognostic (2.83e-1)" "unprognostic (2.45e-1)" "unprognostic (1.12e-3)" "unprognostic (9.98e-2)" "unprognostic (9.36e-2)" "unprognostic (2.45e-2)" "unprognostic (7.04e-2)" HAND1 "bHLHa27, eHand, Hxt, Thing1" ENSG00000113196 "Heart and neural crest derivatives expressed 1" O96004 5 154474972-154478227 "Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 23.1;intestine: 63.4" "Cell type enriched" "Detected in some" 4 "Smooth muscle cells: 12.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 5.2" "Region enriched" "Detected in single" 4 "thalamus: 3.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "Neuroblastoma: 88.8;testis cancer: 195.7" "Adrenal gland - Adrenal medulla cells, Heart muscle - Cardiomyocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA040925, HPA075313" Uncertain Approved "Nucleoplasm,Nuclear membrane,Nuclear bodies" NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 108: Fibroblasts - ECM organization" 5 Nucleoplasm "Nuclear membrane, Nuclear bodies" "HPA040925: , HPA075313: " "unprognostic (1.53e-1)" "unprognostic (1.18e-1)" "unprognostic (1.41e-1)" "unprognostic (5.41e-2)" HAND2 "bHLHa26, dHand, Hed, Thing2" ENSG00000164107 "Heart and neural crest derivatives expressed 2" P61296 4 173524969-173530229 "Predicted intracellular proteins, Transcription factors" "Angiogenesis, Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 101.2" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 180.8;Decidual stromal cells: 211.2;Endometrial stromal cells: 270.0;Epicardial cells: 70.5;Hepatic stellate cells: 77.5;Ovarian stromal cells: 93.4;Schwann cells: 158.3;Smooth muscle cells: 53.6" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Pancreatic Adenocarcinoma (TCGA): 9.1;Stomach Adenocarcinoma (TCGA): 8.4" "Region enhanced" "Detected in single" "cerebellum: 1.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 16 "Neuroblastoma: 313.4" "Adrenal gland - Adrenal medulla cells, Breast - Fibroblasts, Heart muscle - Cardiomyocytes, Liver - Hepatic stellate cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA019591, CAB025576" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 35: Non-specific - DNA binding" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 108: Fibroblasts - ECM organization" 9 Nucleoplasm Vesicles "CAB025576: , HPA019591: " "unprognostic (4.66e-3)" "unprognostic (1.20e-1)" "unprognostic (3.17e-3)" "unprognostic (7.33e-2)" "unprognostic (1.08e-1)" "unprognostic (2.86e-2)" "unprognostic (2.68e-3)" "unprognostic (1.54e-1)" "unprognostic (1.93e-1)" "unprognostic (1.20e-1)" "unprognostic (1.70e-1)" "unprognostic (1.95e-2)" "unprognostic (2.19e-2)" "unprognostic (1.89e-1)" "unprognostic (5.84e-2)" HAO1 "GOX, GOX1" ENSG00000101323 "Hydroxyacid oxidase 1" Q9UJM8 20 7882985-7940458 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Amino-acid biosynthesis" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 584 "liver: 568.2" "Cell type enriched" "Detected in some" 34 "Hepatocytes: 439.2" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 179 "Liver Hepatocellular Carcinoma (TCGA): 120.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA049552, HPA072442" Enhanced Supported Vesicles NA NA 310000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 7: Liver cancer - Metabolism" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" Vesicles "HPA049552: , HPA072442: " "unprognostic (1.58e-3)" "unprognostic (3.05e-3)" HAO2 "GIG16, HAOX2" ENSG00000116882 "Hydroxyacid oxidase 2" Q9NYQ3 1 119368779-119394130 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 16 "kidney: 283.1;liver: 397.7" "Group enriched" "Detected in some" 39 "Hepatocytes: 397.1;Proximal tubule cells: 109.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 20 "Kidney Renal Clear Cell Carcinoma (TCGA): 23.1;Kidney Renal Papillary Cell Carcinoma (TCGA): 20.6;Liver Hepatocellular Carcinoma (TCGA): 36.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Sebaceous gland cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA050355 Approved Vesicles,Cytosol NA NA "Cluster 16: Liver & Kidney - Metabolism" "Cluster 53: Neurons - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 93: Hepatocytes - Bile production & excretion" 1 "Vesicles, Cytosol" "HPA050355: " "unprognostic (1.92e-1)" "validated prognostic favorable (1.43e-8)" "validated prognostic favorable (5.51e-6)" "potential prognostic favorable (1.75e-4)" "unprognostic (2.68e-2)" "potential prognostic favorable (1.00e-5)" HAP1 "HAP2, hHLP1, HIP5, HLP" ENSG00000173805 "Huntingtin associated protein 1" P54257 17 41717742-41734644 "Essential proteins, Predicted intracellular proteins" "Autophagy, Cilium biogenesis/degradation, Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 41.7" "Cell type enhanced" "Detected in many" "Bergmann glia: 45.8;Endometrial glandular cells: 155.3;Endometrial luminal cells: 48.3;Epididymal basal cells: 144.8;Epididymal clear cells: 65.3;Medullary thymic epithelial cells: 55.2;Other brain neurons: 44.0;Syncytiotrophoblasts: 51.3;Tuft cells: 138.3" "Cell type enhanced" "Detected in many" "Bergmann glia: 45.0;oligodendrocyte precursor cell: 35.0" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 19.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "Bone cancer: 36.9" "Adrenal gland - Adrenal medulla cells, Pancreas - Alpha cells, Prostate - Prostate basal glandular cells, Stomach - Fibroblasts, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023394, HPA076992" Enhanced Supported Nucleoli,Cytosol NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 51: Secretory epithelial cells - Mixed function" 49 Cytosol Nucleoli "HPA023394: , HPA076992: " "unprognostic (1.22e-1)" "unprognostic (6.87e-2)" "unprognostic (6.04e-2)" "unprognostic (9.09e-2)" "unprognostic (2.80e-1)" "unprognostic (1.72e-1)" "unprognostic (7.02e-2)" "unprognostic (7.96e-2)" "unprognostic (1.42e-2)" "unprognostic (2.35e-3)" "unprognostic (1.28e-3)" "unprognostic (5.56e-3)" "unprognostic (5.61e-3)" "unprognostic (1.63e-1)" "unprognostic (1.98e-2)" "unprognostic (3.93e-1)" HAPLN1 CRTL1 ENSG00000145681 "Hyaluronan and proteoglycan link protein 1" P10915 5 83637805-83720855 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "placenta: 70.3" "Cell type enriched" "Detected in some" 4 "Fibroblasts: 108.4" "Cell type enhanced" "Detected in some" "CGE interneuron: 76.2;LAMP5-LHX6 and Chandelier: 119.2;mammillary body: 53.2" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 10.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 45.0;testis cancer: 64.5" "Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019105, HPA019482, HPA025238" Enhanced Approved Approved Vesicles "Secreted to extracellular matrix" "No annotated function" NA NA 120000 "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 24: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 1 Vesicles "HPA019105: , HPA019482: , HPA025238: " "unprognostic (8.55e-3)" "unprognostic (1.27e-3)" "unprognostic (8.11e-3)" "unprognostic (2.33e-1)" "unprognostic (8.11e-2)" "unprognostic (2.73e-1)" "unprognostic (1.75e-1)" "unprognostic (9.39e-3)" "unprognostic (3.83e-3)" "unprognostic (1.15e-2)" "unprognostic (3.45e-1)" "unprognostic (1.18e-2)" "unprognostic (2.55e-2)" "unprognostic (3.20e-1)" "unprognostic (1.51e-1)" "unprognostic (3.96e-2)" "unprognostic (7.28e-2)" "unprognostic (1.82e-2)" "unprognostic (1.18e-1)" "unprognostic (5.67e-3)" "unprognostic (4.33e-2)" "unprognostic (6.87e-2)" "unprognostic (8.78e-3)" HAPLN2 BRAL1 ENSG00000132702 "Hyaluronan and proteoglycan link protein 2" Q9GZV7 1 156619331-156625725 "Essential proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 95 "brain: 659.7" "Cell type enriched" "Detected in some" 12 "Oligodendrocytes: 333.4" "Cell type enriched" "Detected in all" 5 "oligodendrocyte: 543.6" "Cancer enriched" "Detected in single" 27 "Glioblastoma Multiforme (TCGA): 15.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Rhabdoid: 2.8" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA045765 Enhanced "Secreted in brain" "No annotated function" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 5: Rhabdoid - Unknown function" "Cluster 80: Oligodendrocytes - Myelination" 37 "HPA045765: " "unprognostic (2.60e-2)" "unprognostic (2.40e-1)" "unprognostic (3.53e-2)" HAPLN3 "EXLD1, HsT19883" ENSG00000140511 "Hyaluronan and proteoglycan link protein 3" Q96S86 15 88877294-88895597 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 43.5" "Cell type enriched" "Detected in many" 5 "Extravillous trophoblasts: 1509.2" "Group enriched" "Detected in some" 4 "endothelial cell: 24.4;vascular associated smooth muscle cell: 17.8" "Cancer enhanced" "Detected in all" "Uterine Corpus Endometrial Carcinoma (TCGA): 74.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 51.0" "Lineage enriched" "Detected in all" 5 "T-cells: 51.0" "Cancer enhanced" "Detected in many" "Uterine cancer: 52.1" "Colon - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA039237 Approved Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" "No annotated function" NA NA 60000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 47: Endothelial cells - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 4 "Plasma membrane, Cytosol" "HPA039237: " "unprognostic (1.13e-2)" "unprognostic (2.35e-2)" "unprognostic (7.17e-2)" "unprognostic (4.17e-2)" "unprognostic (1.18e-1)" "unprognostic (4.62e-2)" "unprognostic (1.60e-1)" "unprognostic (2.57e-1)" "unprognostic (6.23e-2)" "unprognostic (2.74e-1)" "unprognostic (1.35e-3)" "unprognostic (3.20e-1)" "potential prognostic unfavorable (5.67e-7)" "unprognostic (3.38e-1)" "unprognostic (3.21e-2)" "unprognostic (2.77e-2)" "unprognostic (8.14e-2)" "unprognostic (1.70e-1)" "unprognostic (1.58e-1)" "unprognostic (6.26e-2)" "unprognostic (7.74e-2)" "unprognostic (1.35e-3)" "unprognostic (4.61e-2)" "unprognostic (1.39e-1)" "unprognostic (4.97e-2)" "unprognostic (2.62e-2)" "unprognostic (6.22e-3)" "unprognostic (1.13e-1)" "unprognostic (5.72e-2)" "unprognostic (1.74e-1)" "unprognostic (3.17e-1)" HAPLN4 "BRAL2, KIAA1926" ENSG00000187664 "Hyaluronan and proteoglycan link protein 4" Q86UW8 19 19254756-19262804 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "brain: 42.1;intestine: 14.5;liver: 11.7" "Group enriched" "Detected in some" 9 "Brain excitatory neurons: 11.8;Brain inhibitory neurons: 12.2;Oligodendrocyte progenitor cells: 3.3;Other brain neurons: 12.3;Proximal tubule cells: 3.1" "Cell type enhanced" "Detected in many" "mammillary body: 54.5" "Cancer enriched" "Detected in some" 6 "Glioblastoma Multiforme (TCGA): 5.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Neuroblastoma: 1.2" "Adrenal gland - Adrenal medulla cells, Kidney - Proximal tubular cells, Pancreas - Beta cells, Prostate - Fibroblasts, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055856 Enhanced "Secreted in brain" "No annotated function" NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 47: Leukemia - Hemostasis" "Cluster 98: Neurons - Neurotransmission & signaling" "HPA055856: " "unprognostic (4.48e-2)" "unprognostic (2.29e-2)" "unprognostic (8.28e-3)" "unprognostic (1.51e-1)" HAPSTR1 "C16orf72, FLJ41272, PRO0149, TAPR1" ENSG00000182831 "HUWE1 associated protein modifying stress responses" Q14CZ0 16 9091644-9121635 "Predicted intracellular proteins" "Stress response" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 100.0" "Cell type enhanced" "Detected in all" "Early spermatids: 258.3;Late spermatids: 1080.7;Neutrophils: 369.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041568, HPA067492" Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 54: Non-specific - Transcription" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 36 Nucleoplasm Vesicles "HPA041568: , HPA067492: " "unprognostic (2.05e-1)" "unprognostic (4.47e-2)" "unprognostic (2.52e-1)" "unprognostic (4.80e-2)" "unprognostic (2.03e-1)" "unprognostic (3.92e-2)" "unprognostic (1.97e-1)" "unprognostic (1.29e-2)" "unprognostic (8.65e-3)" "unprognostic (6.23e-2)" "potential prognostic favorable (2.98e-6)" "unprognostic (1.49e-3)" "unprognostic (1.42e-1)" "unprognostic (7.44e-2)" "unprognostic (3.00e-1)" "unprognostic (5.70e-2)" "unprognostic (1.93e-2)" "unprognostic (1.94e-1)" "unprognostic (1.84e-2)" "unprognostic (1.54e-1)" "unprognostic (3.57e-3)" "unprognostic (2.75e-2)" "unprognostic (2.22e-2)" "unprognostic (1.19e-1)" "unprognostic (3.16e-2)" "unprognostic (2.25e-1)" "unprognostic (7.58e-2)" "unprognostic (1.14e-1)" "unprognostic (9.60e-2)" "unprognostic (2.00e-2)" "unprognostic (6.86e-2)" HARBI1 "C11orf77, FLJ32675" ENSG00000180423 "Harbinger transposase derived 1" Q96MB7 11 46602861-46617909 "Predicted intracellular proteins" "Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 11.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 92.7;Early spermatids: 92.2;Epicardial cells: 45.5;Late primary spermatocytes: 34.8;Late spermatids: 110.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038671, HPA045457" Approved Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 32: Basophils - Transcription" "Cluster 39: Testis - Nuclear processes" "Cluster 11: White matter - Signal transduction" "Cluster 24: Non-specific - Unknown function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 1 "Plasma membrane, Cytosol" "HPA038671: , HPA045457: " "unprognostic (9.03e-2)" "unprognostic (2.00e-3)" "unprognostic (5.43e-2)" "unprognostic (4.73e-2)" "unprognostic (3.34e-2)" "unprognostic (6.31e-2)" "unprognostic (5.50e-2)" "unprognostic (4.36e-3)" "unprognostic (6.77e-2)" "unprognostic (1.03e-2)" "unprognostic (1.96e-1)" "unprognostic (2.75e-1)" "unprognostic (4.18e-2)" "potential prognostic unfavorable (1.20e-8)" "unprognostic (1.71e-2)" "unprognostic (4.93e-1)" "unprognostic (1.13e-1)" "unprognostic (2.05e-1)" "unprognostic (1.14e-1)" "unprognostic (2.97e-1)" "unprognostic (2.71e-2)" "unprognostic (1.20e-1)" "unprognostic (2.17e-1)" "unprognostic (2.43e-1)" "unprognostic (2.47e-2)" "unprognostic (4.31e-2)" "unprognostic (8.25e-2)" "unprognostic (2.70e-1)" "unprognostic (1.93e-1)" "unprognostic (3.08e-1)" "unprognostic (2.00e-1)" HARS1 "HARS, HisRS, USH3B" ENSG00000170445 "Histidyl-tRNA synthetase 1" P12081 5 140673035-140691537 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Charcot-Marie-Tooth disease, Deafness, Disease variant, Neurodegeneration, Neuropathy, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036539 Approved Enhanced Cytosol NA NA 570000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 1: Neurons - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 93: Hepatocytes - Bile production & excretion" 8 Cytosol "HPA036539: " "unprognostic (2.01e-1)" "unprognostic (8.65e-2)" "unprognostic (1.22e-3)" "unprognostic (1.46e-1)" "unprognostic (6.78e-2)" "unprognostic (8.88e-2)" "unprognostic (5.18e-3)" "unprognostic (5.18e-2)" "unprognostic (2.53e-2)" "validated prognostic favorable (9.32e-5)" "validated prognostic favorable (8.25e-4)" "unprognostic (3.88e-2)" "potential prognostic unfavorable (1.60e-7)" "unprognostic (8.05e-3)" "unprognostic (5.25e-3)" "unprognostic (1.85e-1)" "unprognostic (1.77e-2)" "unprognostic (2.62e-1)" "unprognostic (1.30e-1)" "unprognostic (9.22e-2)" "unprognostic (4.94e-2)" "unprognostic (3.56e-1)" "unprognostic (4.60e-1)" "unprognostic (2.73e-1)" "unprognostic (1.07e-1)" "unprognostic (3.18e-2)" "unprognostic (5.64e-2)" "unprognostic (2.27e-1)" "unprognostic (1.16e-1)" HARS2 "HARSL, HARSR, HO3" ENSG00000112855 "Histidyl-tRNA synthetase 2, mitochondrial" P49590 5 140691430-140699305 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035941, HPA075303" Approved Approved Mitochondria NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 7: Non-specific - Transcription" 62 Mitochondria "HPA035941: , HPA075303: " "unprognostic (1.52e-1)" "unprognostic (3.02e-3)" "unprognostic (1.59e-1)" "unprognostic (3.61e-3)" "unprognostic (2.78e-2)" "unprognostic (5.39e-3)" "unprognostic (1.26e-1)" "unprognostic (5.30e-3)" "unprognostic (1.78e-2)" "unprognostic (9.29e-3)" "potential prognostic favorable (1.38e-5)" "unprognostic (3.00e-2)" "unprognostic (8.09e-2)" "unprognostic (2.73e-3)" "unprognostic (9.09e-3)" "unprognostic (5.07e-2)" "unprognostic (3.48e-2)" "unprognostic (1.00e-1)" "unprognostic (1.79e-1)" "unprognostic (7.30e-2)" "unprognostic (2.64e-1)" "unprognostic (1.12e-1)" "unprognostic (8.78e-2)" "unprognostic (2.50e-1)" "unprognostic (3.16e-2)" "unprognostic (1.57e-1)" "unprognostic (2.73e-1)" "unprognostic (2.13e-1)" "unprognostic (1.24e-1)" "unprognostic (8.15e-2)" "unprognostic (2.20e-1)" HAS1 HAS ENSG00000105509 "Hyaluronan synthase 1" Q92839 19 51713112-51723991 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 46.2;ovary: 19.3" "Group enriched" "Detected in some" 5 "Epicardial cells: 270.6;Mesothelial cells: 255.9" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Pancreatic Adenocarcinoma (TCGA): 4.1" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 4 "eosinophil: 2.5" "Lineage enriched" "Detected in single" 18 "granulocytes: 2.5" "Cancer enhanced" "Detected in some" "Neuroblastoma: 3.4" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA067602 Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 1: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 103: Non-specific - Basic cellular processes" 2 "Plasma membrane" Nucleoplasm "HPA067602: " "unprognostic (1.11e-1)" "unprognostic (6.43e-2)" "unprognostic (4.83e-3)" "unprognostic (1.96e-1)" "unprognostic (1.17e-2)" "unprognostic (1.00e-1)" "unprognostic (2.99e-1)" "unprognostic (1.96e-1)" HAS2 ENSG00000170961 "Hyaluronan synthase 2" Q92819 8 121612116-121641440 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 21.2;urinary bladder: 19.0" "Cell type enhanced" "Detected in some" "Decidual stromal cells: 36.9;Early spermatids: 111.4;Epididymal basal cells: 33.0;Fibro-adipogenic progenitors: 55.8;Fibroblasts: 121.6;Late primary spermatocytes: 35.2;Medullary thymic epithelial cells: 40.8;Oligodendrocyte progenitor cells: 44.0;Pericytes: 32.3;Prostatic hillock cells: 24.6;Schwann cells: 26.6" "Group enriched" "Detected in some" 8 "astrocyte: 12.9;committed oligodendrocyte precursor: 50.4;ependymal cell: 19.0;oligodendrocyte precursor cell: 47.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Fibroblasts, Prostate - Urothelial cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 2 "unprognostic (1.53e-2)" "unprognostic (8.04e-2)" "unprognostic (3.31e-2)" "unprognostic (1.63e-1)" "unprognostic (2.03e-1)" "unprognostic (1.82e-1)" "unprognostic (2.62e-1)" "unprognostic (3.48e-2)" "unprognostic (1.95e-2)" "unprognostic (1.22e-1)" "unprognostic (6.65e-2)" "unprognostic (6.48e-2)" "unprognostic (1.07e-2)" "unprognostic (2.31e-1)" "unprognostic (1.51e-3)" "unprognostic (3.83e-3)" "unprognostic (6.48e-3)" "unprognostic (2.21e-2)" "unprognostic (2.45e-1)" "unprognostic (4.49e-2)" "unprognostic (9.61e-2)" "unprognostic (8.14e-3)" "unprognostic (4.62e-2)" "unprognostic (1.60e-1)" HAS3 ENSG00000103044 "Hyaluronan synthase 3" O00219 16 69105653-69118719 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 32.1;urinary bladder: 86.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 127.4;Epididymal basal cells: 109.4;Esophageal apical cells: 28.7;Esophageal basal cells: 79.2;Esophageal suprabasal cells: 92.4;Late spermatids: 35.9;Suprabasal keratinocytes: 109.0;Urothelial cells: 114.3" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 88.5;Lung Squamous Cell Carcinoma (TCGA): 69.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 100.8;Gallbladder cancer: 185.3" "Breast - Breast myoepithelial cells, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA031554, CAB033850" Supported Approved Microtubules NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 15: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 26: Keratinocytes - Keratinization" 4 Microtubules "CAB033850: , HPA031554: " "unprognostic (8.07e-2)" "unprognostic (4.21e-2)" "unprognostic (3.52e-1)" "unprognostic (2.28e-2)" "unprognostic (3.12e-1)" "unprognostic (3.79e-3)" "unprognostic (4.83e-2)" "unprognostic (7.88e-2)" "unprognostic (8.82e-3)" "unprognostic (2.06e-1)" "unprognostic (9.25e-2)" "unprognostic (1.34e-2)" "unprognostic (2.22e-2)" "unprognostic (1.66e-1)" "unprognostic (3.46e-2)" "unprognostic (1.88e-1)" "unprognostic (1.67e-2)" "unprognostic (1.03e-1)" "unprognostic (1.25e-1)" "potential prognostic unfavorable (8.68e-4)" "unprognostic (2.33e-1)" "unprognostic (1.47e-1)" "unprognostic (1.65e-1)" "unprognostic (3.32e-1)" "unprognostic (1.88e-1)" "unprognostic (8.34e-3)" "unprognostic (1.34e-1)" "unprognostic (2.30e-2)" "unprognostic (9.66e-3)" HASPIN GSG2 ENSG00000177602 "Histone H3 associated protein kinase" Q8TF76 17 3723903-3726699 "Enzymes, Predicted intracellular proteins" "Cell cycle" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.7;lymphoid tissue: 5.0;testis: 6.8" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 3.8;Early primary spermatocytes: 3.7;Early spermatids: 17.2;Erythrocyte progenitors: 5.0;Extravillous trophoblasts: 3.6;Late primary spermatocytes: 34.1;Late spermatids: 9.7;Megakaryocyte progenitors: 6.6;Monocyte progenitors: 7.1;Plasma cells: 3.4" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Breast - T-cells, Colon - Mitotic cells (Colon), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Prostate - T-cells, Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Testis - Early spermatids, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA027422, HPA030698" Approved Supported Nucleoplasm NA NA "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 42: Non-specific - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 11 Nucleoplasm "HPA027422: , HPA030698: " "potential prognostic unfavorable (9.69e-4)" "unprognostic (2.01e-2)" "unprognostic (3.55e-1)" "unprognostic (5.38e-2)" "unprognostic (7.00e-2)" "unprognostic (3.39e-1)" "unprognostic (2.08e-3)" "unprognostic (9.10e-2)" "potential prognostic unfavorable (7.25e-5)" "unprognostic (2.93e-2)" "unprognostic (1.24e-1)" "unprognostic (3.65e-2)" "unprognostic (1.88e-1)" "unprognostic (2.47e-1)" "unprognostic (9.11e-2)" "unprognostic (1.95e-2)" "unprognostic (5.83e-2)" "unprognostic (1.35e-1)" "unprognostic (3.06e-2)" "unprognostic (8.87e-2)" "unprognostic (1.60e-1)" HAT1 KAT1 ENSG00000128708 "Histone acetyltransferase 1" O14929 2 171922448-171983686 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036788, CAB037191" Supported Supported Nucleoplasm NA NA 18000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 57 Nucleoplasm "CAB037191: , HPA036788: " "unprognostic (1.24e-2)" "unprognostic (5.73e-2)" "unprognostic (8.78e-2)" "unprognostic (2.31e-1)" "unprognostic (8.84e-2)" "unprognostic (8.40e-2)" "unprognostic (1.71e-1)" "unprognostic (1.53e-3)" "unprognostic (1.01e-1)" "unprognostic (3.75e-2)" "potential prognostic favorable (7.45e-7)" "unprognostic (2.40e-2)" "unprognostic (1.14e-1)" "validated prognostic unfavorable (3.25e-5)" "validated prognostic unfavorable (1.26e-6)" "unprognostic (5.42e-3)" "unprognostic (3.26e-2)" "unprognostic (9.69e-3)" "unprognostic (4.02e-1)" "unprognostic (1.74e-1)" "unprognostic (7.04e-2)" "unprognostic (1.85e-2)" "unprognostic (9.04e-3)" "unprognostic (3.46e-1)" "unprognostic (9.14e-2)" "unprognostic (8.31e-2)" "unprognostic (4.20e-2)" "unprognostic (3.71e-2)" "unprognostic (2.62e-1)" "unprognostic (2.20e-1)" "unprognostic (1.56e-2)" HAUS1 "CCDC5, FLJ40084, HEI-C, HsT1461" ENSG00000152240 "HAUS augmin like complex subunit 1" Q96CS2 18 46104378-46128333 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 133.3;Migrating cytotrophoblasts: 107.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Macrophages, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040601, HPA040652" Supported Supported "Centrosome,Cytosol,Mid piece,End piece" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 21: Non-specific - Metabolism" "Cluster 13: Non-specific - Mixed function" "Cluster 27: Non-specific - Cell proliferation" 120 Cytosol "Centrosome, Mid piece, End piece" "HPA040601: , HPA040652: " "unprognostic (7.30e-2)" "unprognostic (8.02e-2)" "unprognostic (1.00e-1)" "unprognostic (2.99e-2)" "unprognostic (6.49e-2)" "unprognostic (8.00e-2)" "unprognostic (4.88e-1)" "unprognostic (2.36e-2)" "unprognostic (1.01e-1)" "unprognostic (2.92e-2)" "potential prognostic favorable (1.93e-4)" "unprognostic (1.91e-1)" "unprognostic (2.82e-1)" "validated prognostic unfavorable (9.13e-5)" "validated prognostic unfavorable (1.36e-6)" "unprognostic (1.34e-1)" "unprognostic (1.29e-1)" "unprognostic (4.17e-2)" "unprognostic (4.68e-2)" "unprognostic (1.18e-2)" "unprognostic (8.89e-2)" "unprognostic (1.03e-1)" "unprognostic (1.13e-1)" "unprognostic (9.15e-3)" "unprognostic (1.47e-1)" "unprognostic (1.67e-1)" "unprognostic (1.55e-2)" "unprognostic (8.16e-2)" "unprognostic (9.50e-3)" "unprognostic (9.92e-3)" "unprognostic (1.28e-2)" HAUS2 "C15orf25, CEP27, FLJ10460, HsT17025" ENSG00000137814 "HAUS augmin like complex subunit 2" Q9NVX0 15 42548828-42569994 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 34.4" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 85.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039965 Approved Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 75: Non-specific - Chaperones and protein folding" 20 "Nucleoplasm, Cytosol" Centrosome "HPA039965: " "unprognostic (3.34e-1)" "unprognostic (9.97e-3)" "unprognostic (3.43e-2)" "unprognostic (1.64e-2)" "unprognostic (7.93e-2)" "unprognostic (2.41e-1)" "unprognostic (2.86e-1)" "unprognostic (3.77e-1)" "unprognostic (2.69e-3)" "unprognostic (5.94e-2)" "potential prognostic favorable (4.10e-5)" "unprognostic (2.59e-3)" "unprognostic (1.01e-1)" "unprognostic (1.72e-3)" "potential prognostic unfavorable (3.06e-5)" "unprognostic (5.16e-2)" "unprognostic (2.40e-2)" "unprognostic (2.04e-1)" "unprognostic (4.19e-2)" "unprognostic (3.50e-1)" "unprognostic (2.89e-1)" "potential prognostic unfavorable (3.72e-4)" "unprognostic (1.75e-2)" "unprognostic (4.83e-3)" "unprognostic (1.92e-1)" "unprognostic (1.14e-1)" "unprognostic (3.84e-1)" "unprognostic (5.49e-2)" "unprognostic (5.35e-2)" "unprognostic (9.29e-2)" "unprognostic (7.60e-3)" HAUS3 "C4orf15, dgt3, IT1, MGC4701" ENSG00000214367 "HAUS augmin like complex subunit 3" Q68CZ6 4 2227464-2242133 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 25.4" "Cell type enhanced" "Detected in some" "Astrocytes: 3.1;Bergmann glia: 3.7;Brain excitatory neurons: 5.0;Brain inhibitory neurons: 3.3;Ependymal cells: 1.6;Microglia: 4.0;Oligodendrocyte progenitor cells: 2.7;Oligodendrocytes: 2.5;Other brain neurons: 3.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040649, HPA048190" Approved Approved "Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Basal body" Yes No "Cluster 3: Non-specific - Nuclear processes" "Cluster 15: Bone marrow - Innate immune response" "Cluster 2: Neurons - Nucleosome" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 98: Neurons - Neurotransmission & signaling" 25 "Microtubules, Primary cilium" "Cytokinetic bridge, Mitotic spindle, Basal body" "HPA040649: , HPA048190: " "unprognostic (9.79e-2)" "unprognostic (7.83e-3)" "unprognostic (1.20e-1)" "unprognostic (1.74e-1)" "unprognostic (3.81e-1)" "unprognostic (1.75e-1)" "unprognostic (3.51e-1)" "unprognostic (4.23e-2)" "unprognostic (1.26e-3)" "potential prognostic unfavorable (5.52e-5)" "unprognostic (1.50e-2)" "unprognostic (5.96e-2)" "unprognostic (6.50e-2)" "unprognostic (1.86e-2)" "unprognostic (8.17e-3)" "unprognostic (2.27e-2)" "unprognostic (2.06e-2)" "unprognostic (1.62e-1)" "unprognostic (7.86e-2)" "unprognostic (3.20e-1)" "unprognostic (6.38e-2)" "unprognostic (8.64e-2)" "unprognostic (9.37e-3)" "unprognostic (4.47e-3)" "unprognostic (1.86e-3)" "unprognostic (6.04e-2)" "unprognostic (3.71e-1)" "unprognostic (3.98e-2)" "unprognostic (1.69e-1)" "unprognostic (2.97e-2)" "unprognostic (2.31e-1)" HAUS4 "C14orf94, FLJ20424" ENSG00000092036 "HAUS augmin like complex subunit 4" Q9H6D7 14 22946228-22957161 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enteric stem cells: 45.7;Enteric transient amplifying cells: 44.3;Microglia: 37.7;Paneth cells: 38.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029803 Approved NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 54: Non-specific - Ribosome" "Cluster 55: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 15: Non-specific - Protein processing" 19 "HPA029803: " "unprognostic (4.45e-3)" "unprognostic (2.64e-2)" "unprognostic (9.68e-2)" "unprognostic (1.52e-1)" "unprognostic (3.72e-2)" "unprognostic (4.04e-2)" "unprognostic (2.58e-1)" "unprognostic (3.64e-2)" "unprognostic (7.93e-2)" "unprognostic (6.38e-2)" "potential prognostic favorable (2.47e-5)" "unprognostic (2.41e-2)" "unprognostic (1.45e-1)" "unprognostic (1.60e-2)" "unprognostic (3.02e-3)" "unprognostic (2.97e-1)" "unprognostic (3.80e-3)" "unprognostic (2.24e-3)" "unprognostic (8.53e-2)" "unprognostic (1.90e-1)" "unprognostic (4.14e-2)" "unprognostic (1.19e-1)" "unprognostic (7.96e-2)" "unprognostic (7.09e-2)" "unprognostic (2.76e-2)" "unprognostic (2.31e-1)" "unprognostic (3.97e-2)" "unprognostic (1.78e-2)" "unprognostic (1.93e-1)" "unprognostic (2.54e-1)" "unprognostic (1.87e-1)" HAUS5 "dgt5, KIAA0841" ENSG00000249115 "HAUS augmin like complex subunit 5" O94927 19 35612735-35625355 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Early primary spermatocytes: 119.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067250 Approved NA NA "Cluster 24: Non-specific - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 4: Non-specific - Transcription" "Cluster 3: Early primary spermatocytes - Early meiosis" 18 "HPA067250: " "unprognostic (1.22e-2)" "unprognostic (4.19e-2)" "unprognostic (2.93e-1)" "unprognostic (2.40e-2)" "unprognostic (2.33e-1)" "unprognostic (3.64e-1)" "unprognostic (2.48e-1)" "unprognostic (1.74e-1)" "unprognostic (4.27e-1)" "unprognostic (1.77e-1)" "potential prognostic unfavorable (1.22e-7)" "unprognostic (1.80e-2)" "unprognostic (6.69e-2)" "potential prognostic unfavorable (7.69e-4)" "unprognostic (1.45e-1)" "unprognostic (1.88e-1)" "unprognostic (1.08e-1)" "potential prognostic favorable (1.13e-4)" "unprognostic (2.85e-1)" "unprognostic (1.49e-1)" "unprognostic (2.47e-2)" "unprognostic (2.26e-1)" "unprognostic (1.21e-2)" "unprognostic (1.28e-1)" "unprognostic (1.06e-1)" "unprognostic (2.73e-2)" "unprognostic (1.61e-1)" "unprognostic (2.69e-3)" "unprognostic (3.09e-2)" "unprognostic (3.73e-3)" "unprognostic (1.35e-2)" HAUS6 "dgt6, FAM29A, FLJ20060, KIAA1574" ENSG00000147874 "HAUS augmin like complex subunit 6" Q7Z4H7 9 19053141-19102904 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 88.0;Early spermatids: 132.1;Erythrocyte progenitors: 101.5;Late primary spermatocytes: 92.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020960, HPA020965" Approved Approved "Nuclear speckles,Centriolar satellite,Cytosol,Acrosome,Connecting piece,Mid piece,Principal piece" No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 55: Non-specific - Transcription" "Cluster 47: Leukemia - Hemostasis" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 33 "Centriolar satellite, Cytosol, Acrosome" "Nuclear speckles, Connecting piece, Mid piece, Principal piece" "HPA020960: , HPA020965: " "unprognostic (4.97e-2)" "unprognostic (1.90e-1)" "unprognostic (7.29e-2)" "unprognostic (2.81e-2)" "unprognostic (2.90e-1)" "unprognostic (1.05e-1)" "unprognostic (1.31e-1)" "unprognostic (4.91e-2)" "unprognostic (1.89e-1)" "unprognostic (3.21e-3)" "unprognostic (5.89e-2)" "unprognostic (2.03e-1)" "unprognostic (2.57e-2)" "potential prognostic unfavorable (7.60e-5)" "unprognostic (2.80e-2)" "unprognostic (5.28e-2)" "potential prognostic unfavorable (5.06e-4)" "unprognostic (2.55e-2)" "unprognostic (4.57e-2)" "unprognostic (2.55e-1)" "unprognostic (3.20e-1)" "unprognostic (2.09e-2)" "unprognostic (5.32e-3)" "unprognostic (1.14e-2)" "unprognostic (9.53e-3)" "unprognostic (7.00e-2)" "unprognostic (3.45e-2)" "unprognostic (8.78e-2)" "unprognostic (4.87e-1)" "unprognostic (2.17e-2)" "unprognostic (2.69e-2)" HAUS7 "UCHL5IP, UIP1" ENSG00000213397 "HAUS augmin like complex subunit 7" Q99871 X 153447668-153495516 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 100.2" "Cell type enhanced" "Detected in some" "Astrocytes: 23.2;Brain excitatory neurons: 10.1;Brain inhibitory neurons: 6.2;Ependymal cells: 4.2;Fibroblasts: 4.5;Hepatic stellate cells: 6.5;Microglia: 8.4;Oligodendrocyte progenitor cells: 37.9;Oligodendrocytes: 5.7;Other brain neurons: 4.0;Pericytes: 5.3;Vascular smooth muscle cells: 4.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003614 Approved "Nucleoli,Plasma membrane,Centrosome,Basal body,Mid piece,Principal piece" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 34: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 26 "Plasma membrane, Centrosome" "Nucleoli, Basal body, Mid piece, Principal piece" "HPA003614: " "unprognostic (4.51e-3)" "unprognostic (1.11e-1)" "unprognostic (3.36e-2)" "potential prognostic favorable (3.26e-5)" "unprognostic (1.03e-1)" "unprognostic (1.11e-1)" "potential prognostic unfavorable (3.54e-4)" "unprognostic (3.70e-2)" "unprognostic (3.32e-2)" "unprognostic (7.81e-2)" "unprognostic (1.51e-1)" "unprognostic (9.61e-2)" "unprognostic (7.29e-3)" "validated prognostic unfavorable (5.89e-4)" "validated prognostic unfavorable (6.78e-4)" "unprognostic (2.22e-2)" "potential prognostic unfavorable (8.78e-4)" "unprognostic (5.28e-2)" "unprognostic (2.11e-1)" "unprognostic (2.57e-1)" "unprognostic (2.98e-2)" "unprognostic (6.30e-3)" "unprognostic (2.99e-1)" "unprognostic (4.34e-2)" "unprognostic (1.84e-1)" "unprognostic (1.28e-1)" "unprognostic (5.72e-2)" "unprognostic (3.19e-2)" "unprognostic (1.16e-1)" "unprognostic (1.74e-2)" "unprognostic (3.26e-2)" HAUS8 "HICE1, MGC20533, NY-SAR-48" ENSG00000131351 "HAUS augmin like complex subunit 8" Q9BT25 19 17049729-17075625 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 58.5;Early primary spermatocytes: 53.4;Migrating cytotrophoblasts: 44.3;Oocytes: 78.3;Undifferentiated spermatogonia: 42.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039406 Uncertain NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 15: Non-specific - Transcription" "Cluster 23: Non-specific - Transcription" "Cluster 27: Non-specific - Cell proliferation" 29 "HPA039406: " "unprognostic (3.61e-1)" "unprognostic (1.50e-1)" "unprognostic (1.69e-1)" "potential prognostic favorable (2.57e-4)" "unprognostic (2.32e-1)" "unprognostic (9.09e-2)" "unprognostic (2.69e-1)" "unprognostic (2.70e-1)" "unprognostic (8.85e-2)" "unprognostic (1.82e-1)" "unprognostic (2.42e-3)" "unprognostic (3.56e-2)" "unprognostic (1.09e-2)" "unprognostic (1.70e-3)" "unprognostic (4.45e-3)" "unprognostic (1.24e-2)" "unprognostic (3.25e-3)" "unprognostic (5.97e-2)" "unprognostic (3.13e-3)" "unprognostic (1.74e-1)" "unprognostic (2.58e-2)" "unprognostic (8.07e-3)" "unprognostic (2.89e-2)" "unprognostic (1.86e-2)" "unprognostic (7.03e-2)" "unprognostic (8.09e-2)" "unprognostic (1.16e-1)" "unprognostic (7.43e-3)" "unprognostic (2.15e-1)" "unprognostic (2.94e-2)" "unprognostic (5.80e-2)" HAVCR1 "CD365, HAVCR, HAVCR-1, KIM1, TIM-1, TIM1, TIMD1" ENSG00000113249 "Hepatitis A virus cellular receptor 1" Q96D42 5 157026742-157069396 "CD markers, Predicted membrane proteins" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 4.3;kidney: 6.5" "Cell type enriched" "Detected in some" 5 "Proximal tubule cells: 70.5" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 9.9" "Group enriched" "Detected in many" 13 "Kidney Renal Clear Cell Carcinoma (TCGA): 56.0;Kidney Renal Papillary Cell Carcinoma (TCGA): 69.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 2.5" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in many" 4 "Kidney cancer: 194.7" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "HPA007173, CAB075697" Uncertain Uncertain Vesicles NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 72: Kidney - Transmembrane transport" "Cluster 48: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 88: Proximal tubular cells - Transmembrane transport" 2 Vesicles "CAB075697: , HPA007173: " "unprognostic (1.86e-1)" "unprognostic (1.46e-1)" "unprognostic (6.17e-3)" "potential prognostic favorable (7.21e-5)" "unprognostic (1.70e-1)" "unprognostic (1.79e-1)" "unprognostic (6.57e-3)" "unprognostic (4.63e-3)" "unprognostic (2.10e-3)" "unprognostic (7.53e-2)" "unprognostic (1.22e-3)" "unprognostic (1.59e-2)" "unprognostic (6.01e-3)" "unprognostic (6.89e-2)" "unprognostic (7.39e-3)" "unprognostic (9.04e-2)" "unprognostic (2.35e-2)" HAVCR2 "CD366, FLJ14428, Tim-3, TIM3, TIMD3" ENSG00000135077 "Hepatitis A virus cellular receptor 2" Q8TDQ0 5 157085422-157142869 "CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Inflammatory response, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "cDC: 137.3;Hofbauer cells: 197.0;Kupffer cells: 191.7;Macrophages: 175.5;Mast cells: 67.9;Microglia: 220.7;monocytes: 168.2;NK-cells: 174.7;Proximal tubule cells: 61.1" "Cell type enriched" "Detected in all" 4 "central nervous system macrophage: 280.0" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 61.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 57.2;intermediate monocyte: 62.7;myeloid DC: 118.8;NK-cell: 76.0;non-classical monocyte: 45.9" "Group enriched" "Detected in all" 6 "dendritic cells: 118.8;monocytes: 62.7;NK-cells: 76.0" "Cancer enhanced" "Detected in some" "lymphoma: 10.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Proximal tubular cells, Minor Salivary Gland - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" CAB026003 Enhanced NA NA 9000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 7 "CAB026003: " "unprognostic (4.39e-3)" "unprognostic (1.35e-1)" "unprognostic (1.80e-1)" "unprognostic (2.38e-1)" "unprognostic (1.03e-1)" "unprognostic (1.67e-1)" "unprognostic (2.07e-2)" "unprognostic (1.18e-1)" "unprognostic (7.65e-2)" "unprognostic (7.31e-2)" "potential prognostic favorable (2.67e-4)" "unprognostic (3.51e-2)" "unprognostic (8.67e-3)" "unprognostic (5.30e-2)" "unprognostic (1.90e-1)" "unprognostic (3.03e-2)" "unprognostic (1.56e-3)" "unprognostic (1.13e-1)" "unprognostic (7.09e-2)" "unprognostic (4.97e-2)" "unprognostic (3.32e-1)" "unprognostic (8.70e-2)" "unprognostic (8.27e-3)" "unprognostic (1.69e-1)" "unprognostic (9.67e-2)" "unprognostic (2.95e-2)" "unprognostic (2.25e-1)" "unprognostic (4.83e-2)" "unprognostic (1.80e-2)" "unprognostic (2.56e-1)" "unprognostic (1.29e-1)" HAX1 "HAX-1, HCLSBP1, HS1BP1" ENSG00000143575 "HCLS1 associated protein X-1" O00165 1 154272355-154275875 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 302.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055141, HPA075289" Approved Supported Mitochondria NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 52: Non-specific - Cellular respiration" "Cluster 27: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 67: Plasma cells - Plasma cell differentiation" 46 Mitochondria "HPA055141: , HPA075289: " "unprognostic (6.18e-2)" "unprognostic (5.73e-2)" "unprognostic (1.50e-1)" "unprognostic (2.65e-2)" "unprognostic (2.41e-1)" "unprognostic (2.30e-1)" "unprognostic (1.29e-1)" "unprognostic (1.64e-2)" "unprognostic (1.70e-3)" "potential prognostic unfavorable (6.25e-4)" "potential prognostic favorable (6.45e-4)" "unprognostic (2.01e-1)" "unprognostic (9.22e-3)" "potential prognostic unfavorable (9.45e-4)" "unprognostic (2.79e-2)" "unprognostic (1.07e-1)" "unprognostic (8.83e-3)" "unprognostic (3.64e-2)" "unprognostic (2.46e-1)" "unprognostic (1.08e-1)" "unprognostic (5.45e-2)" "unprognostic (9.62e-2)" "unprognostic (2.67e-1)" "unprognostic (7.42e-2)" "unprognostic (4.56e-1)" "unprognostic (1.46e-1)" "unprognostic (1.45e-1)" "unprognostic (1.91e-1)" "unprognostic (4.32e-2)" "unprognostic (2.22e-1)" "unprognostic (2.80e-2)" HBA1 HBA-T3 ENSG00000206172 "Hemoglobin subunit alpha 1" P69905 16 176680-177522 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Oxygen transport, Transport" "Disease variant, FDA approved drug targets, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "bone marrow: 22913.0" "Cell type enriched" "Detected in many" 9 "Erythrocytes: 129436.6" "Cell type enhanced" "Detected in many" "endothelial cell: 18.7" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 370.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 143.5;plasmacytoid DC: 101.4" "Group enriched" "Detected in all" 5 "dendritic cells: 101.4;granulocytes: 143.5" "Cancer enriched" "Detected in many" 55 "Leukemia: 983.6" "Liver - Erythroid cells, Spleen - Erythrocytes" "CAB032534, HPA043780" Enhanced NA NA 34000000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 47: Leukemia - Hemostasis" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 33 "CAB032534: , HPA043780: " "unprognostic (3.66e-2)" "unprognostic (6.01e-2)" "unprognostic (8.96e-2)" "unprognostic (2.95e-2)" "unprognostic (1.45e-1)" "unprognostic (1.52e-2)" "unprognostic (2.60e-1)" "unprognostic (2.77e-3)" "unprognostic (3.04e-1)" "unprognostic (1.41e-1)" "potential prognostic favorable (2.23e-5)" "unprognostic (2.89e-1)" "unprognostic (6.73e-2)" "unprognostic (1.42e-1)" "unprognostic (1.13e-1)" "unprognostic (3.31e-1)" "unprognostic (1.50e-1)" "unprognostic (6.99e-2)" "unprognostic (8.02e-2)" "unprognostic (1.20e-1)" "unprognostic (1.32e-1)" "unprognostic (1.17e-2)" "unprognostic (2.33e-1)" "unprognostic (2.45e-2)" "unprognostic (4.26e-1)" "unprognostic (2.27e-2)" "unprognostic (6.20e-3)" "unprognostic (3.84e-2)" "unprognostic (5.60e-1)" "unprognostic (4.50e-2)" "unprognostic (1.84e-1)" HBA2 HBA-T2 ENSG00000188536 "Hemoglobin subunit alpha 2" P69905 16 172876-173710 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Oxygen transport, Transport" "Disease variant, FDA approved drug targets, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "bone marrow: 35964.6;lymphoid tissue: 9277.3" "Cell type enriched" "Detected in many" 12 "Erythrocytes: 180862.5" "Cell type enhanced" "Detected in many" "endothelial cell: 40.0;vascular associated smooth muscle cell: 14.1" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 937.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "eosinophil: 316.7;neutrophil: 961.9;plasmacytoid DC: 488.2" "Group enriched" "Detected in all" 7 "dendritic cells: 488.2;granulocytes: 961.9" "Cancer enriched" "Detected in many" 34 "Leukemia: 1053.9" "Liver - Erythroid cells, Spleen - Erythrocytes" "CAB038417, HPA043780" Enhanced NA NA 34000000000 "Cluster 22: Eosinophils - Transcription" "Cluster 15: Bone marrow - Innate immune response" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 47: Leukemia - Hemostasis" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 32 "CAB038417: , HPA043780: " "unprognostic (3.83e-3)" "unprognostic (2.28e-1)" "unprognostic (3.35e-2)" "unprognostic (2.76e-1)" "unprognostic (1.32e-1)" "unprognostic (3.39e-2)" "unprognostic (1.11e-1)" "unprognostic (7.33e-3)" "unprognostic (2.66e-1)" "unprognostic (9.57e-2)" "potential prognostic favorable (1.29e-4)" "unprognostic (9.46e-2)" "unprognostic (2.45e-1)" "unprognostic (2.11e-1)" "unprognostic (9.46e-2)" "unprognostic (2.22e-1)" "unprognostic (1.93e-1)" "unprognostic (1.37e-1)" "unprognostic (1.52e-1)" "unprognostic (2.73e-1)" "unprognostic (4.23e-2)" "unprognostic (1.68e-2)" "unprognostic (1.42e-1)" "unprognostic (2.26e-2)" "unprognostic (2.45e-1)" "unprognostic (1.41e-1)" "unprognostic (4.40e-2)" "unprognostic (4.69e-2)" "unprognostic (2.08e-1)" "unprognostic (7.99e-2)" "unprognostic (3.31e-1)" HBB "beta-globin, CD113t-C" ENSG00000244734 "Hemoglobin subunit beta" P68871 11 5225464-5229395 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Oxygen transport, Transport" "Hypotensive agent, Vasoactive" "Congenital dyserythropoietic anemia, Disease variant, FDA approved drug targets, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 10 "bone marrow: 125480.9" "Cell type enriched" "Detected in some" 9 "Erythrocytes: 521402.5" "Cell type enhanced" "Detected in many" "endothelial cell: 66.8;pericyte: 24.6;vascular associated smooth muscle cell: 41.3" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 1324.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "neutrophil: 662.1;plasmacytoid DC: 380.8" "Group enriched" "Detected in all" 11 "dendritic cells: 380.8;granulocytes: 662.1" "Cancer enriched" "Detected in many" 5 "Leukemia: 132.1" "Liver - Erythroid cells, Spleen - Erythrocytes" "CAB009526, HPA043234" Enhanced NA NA 17000000000 "Cluster 35: Neutrophils - Protein binding" "Cluster 15: Bone marrow - Innate immune response" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 47: Leukemia - Hemostasis" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 38 "CAB009526: , HPA043234: " "unprognostic (2.19e-2)" "unprognostic (2.83e-1)" "unprognostic (2.45e-1)" "unprognostic (5.89e-2)" "unprognostic (9.95e-2)" "unprognostic (4.90e-2)" "unprognostic (2.08e-1)" "unprognostic (1.29e-3)" "unprognostic (4.10e-1)" "unprognostic (2.98e-1)" "potential prognostic favorable (4.13e-7)" "unprognostic (1.09e-1)" "unprognostic (2.15e-2)" "unprognostic (1.23e-1)" "unprognostic (8.02e-2)" "unprognostic (4.04e-2)" "unprognostic (2.00e-1)" "unprognostic (5.63e-2)" "unprognostic (9.17e-2)" "unprognostic (1.71e-1)" "unprognostic (5.58e-2)" "unprognostic (7.82e-2)" "unprognostic (2.30e-1)" "unprognostic (3.54e-3)" "unprognostic (5.07e-1)" "unprognostic (7.81e-2)" "unprognostic (2.71e-2)" "unprognostic (4.90e-2)" "unprognostic (2.42e-1)" "unprognostic (3.08e-2)" "unprognostic (3.31e-1)" HBD ENSG00000223609 "Hemoglobin subunit delta" P02042 11 5232678-5243657 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Oxygen transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 43 "bone marrow: 2634.4" "Group enriched" "Detected in some" 5 "Erythrocyte progenitors: 1338.7;Erythrocytes: 2628.8" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney Renal Clear Cell Carcinoma (TCGA): 1.9" "Region enhanced" "Detected in some" "cerebral cortex: 5.1" "Group enriched" "Detected in some" 5 "eosinophil: 2.1;neutrophil: 2.3;plasmacytoid DC: 1.6" "Group enriched" "Detected in many" 8 "dendritic cells: 1.6;granulocytes: 2.3" "Group enriched" "Detected in some" 15 "Leukemia: 20.4;Myeloma: 39.7" "Liver - Erythroid cells, Pituitary gland - Neutrophils, Spleen - Erythrocytes" "CAB037087, HPA043234" Supported NA NA 8700000000 "Cluster 15: Bone marrow - Innate immune response" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 47: Leukemia - Hemostasis" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 24 "CAB037087: , HPA043234: " "unprognostic (6.05e-2)" "unprognostic (4.54e-2)" "unprognostic (1.90e-1)" HBE1 HBE ENSG00000213931 "Hemoglobin subunit epsilon 1" P02100 11 5268345-5505652 "Plasma proteins, Predicted intracellular proteins" "Oxygen transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in single" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 12 "deep-layer near-projecting: 1.8" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 3.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 7 "Leukemia: 132.5" "Not detected" "Not detected" HPA043234 Approved NA NA 610000000 "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 34: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 6 "HPA043234: " "unprognostic (2.52e-2)" "unprognostic (4.74e-2)" "unprognostic (5.42e-1)" "unprognostic (8.17e-2)" "unprognostic (1.32e-1)" "unprognostic (2.58e-1)" HBEGF "DTR, DTS, HEGFL" ENSG00000113070 "Heparin binding EGF like growth factor" Q99075 5 140332843-140346603 "Predicted membrane proteins, Predicted secreted proteins" "Growth factor, Heparin-binding, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "urinary bladder: 119.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 191.8;Enterocytes: 255.8;Epididymal basal cells: 464.9;Esophageal apical cells: 537.5;Esophageal basal cells: 246.4;Esophageal suprabasal cells: 444.3;monocytes: 289.0;Ocular epithelial cells: 487.0;Suprabasal keratinocytes: 202.5;Urothelial cells: 294.7" "Cell type enhanced" "Detected in many" "endothelial cell: 33.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "intermediate monocyte: 2.2;myeloid DC: 1.6;non-classical monocyte: 1.6" "Group enriched" "Detected in many" 6 "dendritic cells: 1.6;monocytes: 2.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019793, HPA053243" Uncertain Approved "Golgi apparatus,Vesicles" "Secreted to blood" "Growth factor" NA NA 118000 "Cluster 40: Monocytes - Innate immune response" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 16 "Golgi apparatus" Vesicles "HPA019793: , HPA053243: " "unprognostic (8.26e-2)" "unprognostic (8.46e-2)" "unprognostic (1.58e-1)" "unprognostic (9.01e-2)" "unprognostic (5.15e-2)" "unprognostic (2.97e-1)" "unprognostic (5.35e-2)" "unprognostic (3.49e-1)" "potential prognostic unfavorable (8.78e-5)" "unprognostic (6.41e-1)" "unprognostic (5.84e-3)" "unprognostic (2.70e-3)" "unprognostic (2.60e-1)" "unprognostic (8.16e-3)" "unprognostic (2.73e-1)" "unprognostic (1.46e-2)" "unprognostic (8.55e-2)" "unprognostic (1.97e-1)" "unprognostic (9.64e-2)" "unprognostic (1.74e-2)" "unprognostic (7.96e-2)" "potential prognostic unfavorable (4.35e-4)" "unprognostic (9.81e-2)" "unprognostic (6.60e-3)" "unprognostic (4.63e-2)" "unprognostic (1.07e-3)" "unprognostic (9.29e-2)" "unprognostic (7.05e-2)" "unprognostic (2.07e-1)" "unprognostic (1.11e-1)" "unprognostic (2.97e-1)" HBG1 HBG-T2 ENSG00000213934 "Hemoglobin subunit gamma 1" P69891 11 5248269-5249857 "Human disease related genes, Predicted intracellular proteins" "Oxygen transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 94 "placenta: 346.7" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 14 "Glioblastoma Multiforme (TCGA): 2.3;Kidney Renal Clear Cell Carcinoma (TCGA): 4.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 62 "Leukemia: 74.7" "Spleen - Erythrocytes" HPA043234 Approved NA NA 6900000000 "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 47: Leukemia - Hemostasis" "HPA043234: " "unprognostic (5.02e-2)" "unprognostic (5.52e-1)" HBG2 HBG-T1 ENSG00000196565 "Hemoglobin subunit gamma 2" P69892 11 5253188-5505605 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Oxygen transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 131 "placenta: 9659.8" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "Glioblastoma Multiforme (TCGA): 6.2;Kidney Renal Clear Cell Carcinoma (TCGA): 10.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 932 "Leukemia: 3869.3" "Spleen - Erythrocytes" "CAB016143, HPA043234" Approved NA NA 7000000000 "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 17: Choroid plexus - Cilium" "Cluster 47: Leukemia - Hemostasis" 4 "CAB016143: , HPA043234: " "unprognostic (1.71e-2)" "unprognostic (6.33e-2)" "unprognostic (5.07e-2)" "unprognostic (6.23e-3)" "unprognostic (1.54e-1)" "unprognostic (1.36e-1)" HBM "HBAP2, HBK" ENSG00000206177 "Hemoglobin subunit mu" Q6B0K9 16 153892-166764 "Predicted intracellular proteins" "Oxygen transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 26 "bone marrow: 432.7" "Group enriched" "Detected in some" 429 "Erythrocyte progenitors: 902.2;Erythrocytes: 1661.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Leukemia: 2.1" "Liver - Erythroid cells, Spleen - Erythrocytes" "Low region specificity" "Detected in many" NA NA 1300000 "Cluster 15: Bone marrow - Innate immune response" "Cluster 53: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 4 HBP1 ENSG00000105856 "HMG-box transcription factor 1" O60381 7 107168961-107202522 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Late spermatids: 487.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020225, CAB032824" Approved Supported "Nuclear speckles" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 24: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 11 "Nuclear speckles" "CAB032824: , HPA020225: " "unprognostic (2.28e-2)" "unprognostic (2.85e-1)" "unprognostic (3.81e-2)" "unprognostic (2.08e-2)" "unprognostic (5.05e-1)" "unprognostic (1.65e-2)" "unprognostic (7.85e-3)" "unprognostic (2.05e-1)" "unprognostic (4.76e-3)" "unprognostic (1.58e-3)" "validated prognostic favorable (1.03e-9)" "validated prognostic favorable (1.86e-6)" "unprognostic (2.21e-1)" "unprognostic (3.30e-2)" "unprognostic (7.45e-2)" "unprognostic (1.29e-2)" "unprognostic (2.54e-1)" "unprognostic (8.67e-2)" "unprognostic (2.26e-2)" "unprognostic (4.04e-3)" "potential prognostic unfavorable (2.98e-4)" "unprognostic (2.54e-2)" "unprognostic (9.53e-2)" "unprognostic (2.50e-1)" "unprognostic (7.49e-2)" "unprognostic (1.12e-2)" "unprognostic (1.45e-1)" "unprognostic (3.90e-2)" "unprognostic (3.12e-2)" "unprognostic (6.06e-2)" "unprognostic (1.62e-1)" HBQ1 HBQ ENSG00000086506 "Hemoglobin subunit theta 1" P09105 16 180459-181179 "Predicted intracellular proteins" "Oxygen transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 24.1;brain: 13.5" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 49.1;Early primary spermatocytes: 21.2;Erythrocyte progenitors: 87.5;Erythrocytes: 221.7;Megakaryocytes: 80.4;Oocytes: 23.0;Platelets: 105.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 6 "granulocytes: 1.3;T-cells: 1.3" "Cancer enhanced" "Detected in many" "Rhabdoid: 14.3" "Liver - Erythroid cells, Pituitary gland - Corticotropes, Spleen - Erythrocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA062473 Enhanced Approved "Lipid droplets" NA NA 120000 "Cluster 24: Non-specific - Transcription" "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 12 "Lipid droplets" "HPA062473: " "unprognostic (7.46e-3)" "unprognostic (5.86e-2)" "unprognostic (1.34e-1)" "unprognostic (4.38e-1)" HBS1L "DKFZp434g247, EF-1a, eRF3c, ERFS, HBS1, HSPC276, KIAA1038" ENSG00000112339 "HBS1 like translational GTPase" Q9Y450 6 134960378-135103056 "Predicted intracellular proteins, Predicted membrane proteins" "Protein biosynthesis, Translation regulation" "Elongation factor, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythrocyte progenitors: 242.2;Oligodendrocytes: 259.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029728, HPA029729" Approved Approved "Nuclear bodies,Cytosol" NA NA 4800 "Cluster 3: Non-specific - Nuclear processes" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 80: Oligodendrocytes - Myelination" 33 "Nuclear bodies, Cytosol" "HPA029728: , HPA029729: " "unprognostic (3.83e-2)" "potential prognostic unfavorable (8.02e-5)" "unprognostic (3.13e-3)" "unprognostic (5.06e-2)" "unprognostic (2.54e-2)" "unprognostic (1.82e-1)" "unprognostic (7.16e-2)" "unprognostic (5.37e-3)" "unprognostic (2.12e-2)" "unprognostic (4.60e-3)" "potential prognostic favorable (1.75e-5)" "unprognostic (8.26e-2)" "unprognostic (3.72e-1)" "unprognostic (8.44e-3)" "unprognostic (9.58e-2)" "unprognostic (6.94e-2)" "unprognostic (1.24e-2)" "unprognostic (3.38e-1)" "unprognostic (7.25e-2)" "unprognostic (1.31e-2)" "unprognostic (3.31e-3)" "unprognostic (1.48e-1)" "unprognostic (1.00e-2)" "unprognostic (1.26e-1)" "unprognostic (1.91e-2)" "unprognostic (8.59e-3)" "unprognostic (3.32e-1)" "unprognostic (1.28e-1)" "unprognostic (2.96e-1)" "unprognostic (2.45e-1)" "unprognostic (4.97e-2)" HBZ "HBZ-T1, HBZ1" ENSG00000130656 "Hemoglobin subunit zeta" P02008 16 142728-154503 "Predicted intracellular proteins" "Oxygen transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "bone marrow: 3.7;testis: 13.9" "Cell type enriched" "Detected in some" 5 "Late spermatids: 226.8" "Low cell type specificity" "Detected in single" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 74 "Leukemia: 25.2" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA063268, HPA064073, HPA071726" Approved Approved Nucleoplasm,Cytosol NA NA 320000000 "Cluster 67: Testis - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 19 Cytosol Nucleoplasm "HPA063268: , HPA064073: , HPA071726: " HCAR1 "FKSG80, GPR104, GPR81, HCA1, LACR1, TA-GPCR" ENSG00000196917 "Hydroxycarboxylic acid receptor 1" Q9BXC0 12 122726076-122730844 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "breast: 10.8;parathyroid gland: 37.9" "Cell type enhanced" "Detected in some" "Adipocytes: 8.5;Breast hormone-responsive cells: 15.6;Breast myoepithelial cells: 6.0;Early spermatids: 13.6;Epididymal basal cells: 7.6;Extravillous trophoblasts: 5.6;Lacrimal acinar cells: 6.3;Late spermatids: 8.2;Mucous neck cells: 5.1;Papillary tip epithelial cells: 5.3;Renal collecting duct intercalated cells: 11.9;Salivary acinar cells: 9.2;Transitional alveolar cells: 9.1;Urothelial cells: 5.2" "Cell type enhanced" "Detected in some" "fibroblast: 7.4;pericyte: 4.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 1.7" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.7" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 16.6" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Skin - Adipocytes (Skin), Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" NA NA "Cluster 69: Parathyroid gland - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 38: Secretory epithelial cells - Exocrine secretion" "unprognostic (1.27e-1)" "potential prognostic unfavorable (2.90e-4)" "unprognostic (4.07e-3)" "unprognostic (7.86e-2)" "unprognostic (5.89e-2)" "unprognostic (4.35e-2)" "unprognostic (1.02e-1)" "unprognostic (9.55e-2)" "unprognostic (3.56e-2)" "unprognostic (1.59e-1)" "unprognostic (1.04e-1)" "unprognostic (1.26e-2)" "unprognostic (1.82e-2)" "unprognostic (1.63e-2)" "unprognostic (1.98e-1)" "unprognostic (1.16e-1)" "unprognostic (2.01e-1)" "unprognostic (1.36e-1)" "unprognostic (2.26e-1)" "unprognostic (2.26e-1)" "unprognostic (5.01e-3)" HCAR2 "GPR109A, HCA2, HM74A, NIACR1, Puma-g, PUMAG" ENSG00000182782 "Hydroxycarboxylic acid receptor 2" Q8TDS4 12 122701293-122703357 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" Apoptosis "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 39.2;skin 1: 28.9" "Group enriched" "Detected in many" 4 "Epididymal basal cells: 444.6;Esophageal apical cells: 441.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 37.6" "Region enriched" "Detected in some" 5 "cerebral cortex: 12.1" "Immune cell enriched" "Detected in many" 5 "neutrophil: 177.3" "Lineage enriched" "Detected in many" 7 "granulocytes: 177.3" "Cancer enhanced" "Detected in some" "Bladder cancer: 21.1;Esophageal cancer: 21.1;head and neck cancer: 40.0" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Skin - Keratinocyte (other), Testis - Late spermatids" HPA028660 Approved Supported "Cell Junctions" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 84: Apical squamous epithelium - Cornification" "Cell Junctions" "HPA028660: " "unprognostic (1.47e-2)" "unprognostic (3.36e-2)" "unprognostic (6.83e-2)" "unprognostic (2.60e-1)" "unprognostic (3.55e-3)" "unprognostic (6.03e-2)" "unprognostic (2.11e-1)" "unprognostic (3.73e-2)" "unprognostic (1.91e-3)" "unprognostic (6.78e-2)" "unprognostic (2.23e-1)" "unprognostic (1.61e-2)" "unprognostic (3.02e-1)" "unprognostic (3.80e-1)" "unprognostic (7.52e-2)" "unprognostic (4.97e-2)" "unprognostic (5.14e-3)" "unprognostic (1.36e-1)" "unprognostic (1.52e-1)" "unprognostic (7.29e-2)" "unprognostic (2.25e-1)" "unprognostic (5.47e-2)" "unprognostic (1.29e-1)" "unprognostic (1.19e-1)" HCAR3 "GPR109B, HCA3, HM74" ENSG00000255398 "Hydroxycarboxylic acid receptor 3" P49019 12 122714756-122716811 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.8;esophagus: 16.6;lymphoid tissue: 19.2;skin 1: 17.8" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 85.9;Epididymal basal cells: 150.2;Esophageal apical cells: 174.2;Esophageal suprabasal cells: 42.0;Extravillous trophoblasts: 37.8;Neutrophils: 145.6;Ocular epithelial cells: 168.7;Suprabasal keratinocytes: 89.9;Urothelial cells: 147.7" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Bladder Urothelial Carcinoma (TCGA): 12.9;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 13.4;Head and Neck Squamous Cell Carcinoma (TCGA): 16.0;Kidney Chromophobe (TCGA): 4.7;Lung Squamous Cell Carcinoma (TCGA): 10.0" "Region enriched" "Detected in some" 5 "cerebral cortex: 10.1" "Group enriched" "Detected in many" 6 "basophil: 58.8;neutrophil: 177.8;non-classical monocyte: 84.6" "Group enriched" "Detected in many" 50 "granulocytes: 177.8;monocytes: 84.6" "Cancer enhanced" "Detected in some" "Bladder cancer: 7.3;Gallbladder cancer: 6.8;head and neck cancer: 10.4" "Adipose visceral - Adipocytes (Visceral), Lung - NK-cells (Lung), Prostate - Urothelial cells, Skin - Keratinocyte (other)" HPA028660 Approved Approved "Cell Junctions" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" "Cell Junctions" "HPA028660: " "unprognostic (3.12e-2)" "unprognostic (1.91e-1)" "unprognostic (3.74e-2)" "unprognostic (1.68e-1)" "unprognostic (2.19e-2)" "unprognostic (1.55e-1)" "unprognostic (8.99e-2)" "unprognostic (7.01e-2)" "unprognostic (1.11e-1)" "unprognostic (2.22e-1)" "unprognostic (1.53e-1)" "unprognostic (1.85e-1)" "unprognostic (3.28e-1)" "unprognostic (1.67e-2)" "unprognostic (3.26e-2)" "unprognostic (7.27e-2)" "unprognostic (4.07e-2)" "unprognostic (1.12e-1)" "unprognostic (3.47e-1)" HCCS "CCHL, MLS" ENSG00000004961 "Holocytochrome c synthase" P53701 X 11111301-11123086 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Lyase "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal suprabasal cells: 68.4;Oocytes: 101.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002946 Approved Enhanced Mitochondria,Cytosol NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 52: Non-specific - Cellular respiration" "Cluster 23: Choroid plexus - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 22 Mitochondria Cytosol "HPA002946: " "unprognostic (2.61e-1)" "potential prognostic unfavorable (6.04e-5)" "unprognostic (4.75e-2)" "unprognostic (2.26e-2)" "unprognostic (1.39e-2)" "unprognostic (2.44e-2)" "unprognostic (3.12e-1)" "unprognostic (8.69e-2)" "unprognostic (3.47e-2)" "unprognostic (1.65e-2)" "potential prognostic favorable (1.98e-8)" "unprognostic (3.04e-2)" "unprognostic (1.60e-1)" "potential prognostic unfavorable (6.62e-7)" "unprognostic (1.17e-3)" "unprognostic (1.47e-3)" "unprognostic (4.24e-2)" "unprognostic (8.13e-2)" "unprognostic (3.57e-2)" "unprognostic (4.45e-2)" "unprognostic (9.94e-2)" "unprognostic (1.23e-2)" "unprognostic (2.24e-2)" "unprognostic (5.81e-2)" "unprognostic (1.32e-1)" "unprognostic (2.42e-1)" "unprognostic (1.96e-1)" "unprognostic (6.29e-2)" "unprognostic (2.80e-1)" "unprognostic (1.81e-3)" "unprognostic (1.52e-1)" HCFC1 "CFF, HCF-1, HCF1, HFC1, MGC70925, MRX3, PPP1R89, VCAF" ENSG00000172534 "Host cell factor C1" P51610 X 153947557-153971818 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Host-virus interaction" "Chromatin regulator" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078588 Supported Supported Nucleoplasm NA NA 11000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 64: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 129 Nucleoplasm "HPA078588: " "unprognostic (2.94e-1)" "unprognostic (6.61e-3)" "unprognostic (8.22e-2)" "unprognostic (2.37e-1)" "unprognostic (2.25e-1)" "unprognostic (6.23e-2)" "unprognostic (2.85e-1)" "unprognostic (7.98e-2)" "unprognostic (8.98e-2)" "unprognostic (8.67e-3)" "unprognostic (7.56e-2)" "unprognostic (2.36e-1)" "unprognostic (2.28e-1)" "potential prognostic unfavorable (7.84e-6)" "unprognostic (3.42e-2)" "unprognostic (7.18e-3)" "unprognostic (3.37e-3)" "unprognostic (1.01e-2)" "unprognostic (2.66e-3)" "unprognostic (2.60e-1)" "unprognostic (7.07e-3)" "potential prognostic favorable (2.41e-4)" "unprognostic (1.42e-1)" "unprognostic (7.92e-2)" "unprognostic (6.44e-2)" "unprognostic (3.44e-3)" "unprognostic (1.95e-1)" "unprognostic (4.91e-2)" "unprognostic (1.72e-1)" "unprognostic (1.65e-2)" "unprognostic (4.04e-2)" HCFC1R1 "FLJ20568, HPIP" ENSG00000103145 "Host cell factor C1 regulator 1" Q9NWW0 16 3022625-3024286 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 479.9" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 227.0;Hepatic stellate cells: 187.2;Peritubular myoid cells: 171.8;Smooth muscle cells: 188.3;Vascular smooth muscle cells: 229.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Colon - Enteric glia cells, Skeletal muscle - Skeletal myocytes, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059647 Approved Approved Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 54: Non-specific - Transcription" "Cluster 62: Smooth muscle cells - Muscle contraction" 1 Nucleoplasm "HPA059647: " "unprognostic (6.09e-2)" "unprognostic (2.96e-1)" "unprognostic (8.60e-2)" "unprognostic (1.98e-1)" "unprognostic (7.82e-2)" "unprognostic (5.96e-2)" "unprognostic (2.18e-1)" "unprognostic (2.88e-1)" "unprognostic (2.32e-1)" "unprognostic (9.36e-3)" "unprognostic (7.72e-3)" "unprognostic (1.05e-2)" "unprognostic (2.40e-3)" "unprognostic (9.46e-3)" "unprognostic (2.26e-1)" "unprognostic (1.92e-2)" "unprognostic (1.41e-1)" "unprognostic (3.60e-1)" "unprognostic (9.96e-3)" "unprognostic (3.00e-1)" "unprognostic (3.72e-2)" "unprognostic (4.33e-3)" "unprognostic (2.83e-2)" "unprognostic (3.60e-1)" "potential prognostic unfavorable (2.35e-4)" "unprognostic (3.02e-1)" "unprognostic (5.14e-2)" "unprognostic (8.63e-3)" "unprognostic (1.33e-1)" "unprognostic (4.33e-1)" "unprognostic (4.18e-2)" HCFC2 HCF-2 ENSG00000111727 "Host cell factor C2" Q9Y5Z7 12 104064531-104106524 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 235.9;Late primary spermatocytes: 334.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006227 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 75: Ovary - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 33 Nucleoplasm "Plasma membrane, Cytosol" "HPA006227: " "unprognostic (4.93e-2)" "unprognostic (3.66e-3)" "unprognostic (3.60e-1)" "unprognostic (5.43e-2)" "unprognostic (2.83e-2)" "unprognostic (1.34e-1)" "unprognostic (5.65e-2)" "unprognostic (9.87e-3)" "unprognostic (9.55e-2)" "unprognostic (1.44e-1)" "potential prognostic favorable (1.30e-7)" "unprognostic (4.73e-3)" "unprognostic (5.37e-1)" "unprognostic (3.55e-1)" "unprognostic (7.96e-2)" "unprognostic (6.99e-3)" "unprognostic (4.40e-1)" "unprognostic (1.05e-1)" "unprognostic (8.78e-2)" "unprognostic (9.67e-3)" "unprognostic (4.14e-3)" "unprognostic (2.59e-2)" "unprognostic (1.17e-1)" "unprognostic (3.20e-1)" "unprognostic (1.58e-2)" "unprognostic (3.59e-2)" "unprognostic (1.05e-1)" "unprognostic (1.33e-3)" "unprognostic (3.75e-1)" "unprognostic (1.12e-1)" "unprognostic (2.83e-3)" HCG22 "FLJ37114, PBMUCL2" ENSG00000228789 "HLA complex group 22 (gene/pseudogene)" 6 31053450-31059890 "Human disease related genes, Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 6 "Microglia: 133.7" "Cell type enriched" "Detected in some" 13 "central nervous system macrophage: 182.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" HCK JTK9 ENSG00000101336 "HCK proto-oncogene, Src family tyrosine kinase" P08631 20 32052197-32101856 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Exocytosis, Host-virus interaction, Immunity, Inflammatory response, Innate immunity, Phagocytosis" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 106.7" "Cell type enhanced" "Detected in many" "cDC: 207.9;Hofbauer cells: 273.5;Kupffer cells: 311.6;Macrophages: 240.3;Microglia: 233.8;Monocyte progenitors: 186.6;monocytes: 572.5;Neutrophil progenitors: 433.6;Neutrophils: 2704.5;Tuft cells: 979.9" "Group enriched" "Detected in many" 6 "central nervous system macrophage: 286.3;leukocyte: 89.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "classical monocyte: 574.4;eosinophil: 708.2;intermediate monocyte: 1057.2;myeloid DC: 335.8;neutrophil: 803.1;non-classical monocyte: 1255.3" "Group enriched" "Detected in all" 16 "dendritic cells: 335.8;granulocytes: 803.1;monocytes: 1255.3" "Group enriched" "Detected in some" 7 "Leukemia: 25.5;lymphoma: 43.9" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Lung - Neutrophils_2, Minor Salivary Gland - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB005195, HPA035534, HPA063768" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA 69000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 47 Vesicles "Plasma membrane, Cytosol" "CAB005195: , HPA035534: , HPA063768: " "unprognostic (2.79e-2)" "unprognostic (5.35e-2)" "unprognostic (1.17e-2)" "unprognostic (1.40e-2)" "unprognostic (1.32e-1)" "unprognostic (5.35e-2)" "unprognostic (4.34e-2)" "unprognostic (1.70e-1)" "unprognostic (1.86e-1)" "unprognostic (4.12e-2)" "unprognostic (2.97e-2)" "unprognostic (4.77e-1)" "unprognostic (4.09e-2)" "unprognostic (1.99e-2)" "unprognostic (1.94e-1)" "unprognostic (1.44e-2)" "unprognostic (2.35e-2)" "unprognostic (3.97e-1)" "unprognostic (1.58e-1)" "unprognostic (6.78e-2)" "unprognostic (4.63e-1)" "unprognostic (5.84e-2)" "unprognostic (3.56e-2)" "unprognostic (2.71e-2)" "unprognostic (1.93e-2)" "unprognostic (1.32e-2)" "unprognostic (7.90e-2)" "unprognostic (7.14e-2)" "unprognostic (4.50e-2)" "unprognostic (1.61e-1)" "unprognostic (4.94e-2)" HCLS1 "CTTNL, HS1" ENSG00000180353 "Hematopoietic cell-specific Lyn substrate 1" P14317 3 121631399-121660927 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 145.0;lymphoid tissue: 290.6" "Cell type enhanced" "Detected in many" "cDC: 293.7;Kupffer cells: 1301.6;Macrophages: 412.0;Monocyte progenitors: 208.8;monocytes: 470.3;Neutrophil progenitors: 443.0;Neutrophils: 1495.5;Syncytiotrophoblasts: 201.4" "Group enriched" "Detected in many" 16 "central nervous system macrophage: 224.3;leukocyte: 158.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 11 "Leukemia: 188.6;lymphoma: 241.0;Myeloma: 214.2" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Lung - Neutrophils_2, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019143 Enhanced Supported "Plasma membrane,Cytosol" NA NA 880000 "Cluster 7: Non-specific - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 5 "Plasma membrane, Cytosol" "HPA019143: " "unprognostic (1.19e-1)" "unprognostic (2.61e-2)" "unprognostic (2.89e-2)" "unprognostic (7.39e-3)" "unprognostic (1.24e-1)" "unprognostic (1.74e-1)" "unprognostic (1.80e-2)" "unprognostic (3.99e-1)" "unprognostic (8.08e-3)" "unprognostic (6.90e-2)" "unprognostic (9.19e-3)" "unprognostic (5.49e-2)" "unprognostic (1.54e-1)" "unprognostic (4.94e-1)" "unprognostic (2.80e-2)" "unprognostic (9.90e-3)" "unprognostic (6.00e-2)" "unprognostic (8.21e-2)" "unprognostic (5.60e-2)" "unprognostic (1.18e-1)" "unprognostic (2.73e-1)" "unprognostic (2.19e-2)" "unprognostic (4.59e-2)" "unprognostic (3.49e-1)" "unprognostic (5.70e-2)" "unprognostic (6.67e-2)" "unprognostic (4.31e-3)" "unprognostic (2.81e-1)" "unprognostic (4.79e-2)" "unprognostic (1.69e-1)" "unprognostic (3.13e-1)" HCN1 "BCNG-1, BCNG1, HAC-2" ENSG00000164588 "Hyperpolarization activated cyclic nucleotide gated potassium channel 1" O60741 5 45254948-45696498 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Sodium transport, Transport" "Ion channel, Ligand-gated ion channel, Potassium channel, Sodium channel, Voltage-gated channel" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "retina: 16.3" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 287.2;Brain excitatory neurons: 481.9;Brain inhibitory neurons: 419.7;Cone photoreceptor cells: 1863.1;Corticotrophs: 705.0;Retinal amacrine cells: 277.3;Retinal bipolar cells: 275.7;Retinal ganglion cells: 1155.0;Rod photoreceptor cells: 3109.3" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Rhabdoid: 1.4" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pituitary gland - Corticotropes, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019195 Enhanced NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 79: Photoreceptor cells - Phototransduction" 17 "HPA019195: " "unprognostic (2.00e-1)" HCN2 "BCNG-2, BCNG2, HAC-1" ENSG00000099822 "Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2" Q9UL51 19 589881-617159 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ammonia transport, Ion transport, Potassium transport, Sodium transport, Transport" "Ion channel, Ligand-gated ion channel, Potassium channel, Sodium channel, Voltage-gated channel" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "brain: 95.1" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 21.7;Brain inhibitory neurons: 26.4;Endometrial secretory cells: 20.1;Gonadotrophs: 19.8;Oligodendrocytes: 92.0;Other brain neurons: 24.8;Retinal amacrine cells: 31.5;Retinal bipolar cells: 95.0;Retinal ganglion cells: 57.9;Retinal horizontal cells: 26.0;Rod photoreceptor cells: 25.0" "Cell type enhanced" "Detected in all" "oligodendrocyte: 128.2" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 35.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 13.4" "Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Skin - Eccrine sweat gland cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 18: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 2 "unprognostic (5.90e-2)" "unprognostic (7.98e-2)" "unprognostic (7.60e-3)" "unprognostic (4.72e-2)" "unprognostic (5.20e-2)" "unprognostic (5.32e-3)" "unprognostic (7.50e-2)" "unprognostic (2.97e-1)" "unprognostic (2.26e-1)" HCN3 KIAA1535 ENSG00000143630 "Hyperpolarization activated cyclic nucleotide gated potassium channel 3" Q9P1Z3 1 155277463-155289848 "Plasma proteins, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Sodium transport, Transport" "Ion channel, Ligand-gated ion channel, Potassium channel, Sodium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.8" "Cell type enhanced" "Detected in some" "Astrocytes: 2.6;Brain excitatory neurons: 7.7;Brain inhibitory neurons: 10.1;Choroid plexus epithelial cells: 2.9;Distal convoluted tubule cells: 3.0;Ependymal cells: 2.1;Loop of henle epithelial cells: 2.2;Microglia: 2.1;Oligodendrocyte progenitor cells: 5.7;Other brain neurons: 12.2;Proximal tubule cells: 6.2;Renal collecting duct intercalated cells: 2.9;Renal collecting duct principal cells: 2.6;Renal connecting tubule cells: 4.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026584 Approved NA NA "Cluster 64: Non-specific - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 109: Neurons - Neuronal signaling" 1 "HPA026584: " "unprognostic (1.15e-1)" "unprognostic (1.76e-1)" "unprognostic (1.66e-2)" "unprognostic (1.42e-1)" "potential prognostic favorable (2.74e-5)" "unprognostic (1.68e-1)" "unprognostic (1.48e-1)" "unprognostic (2.52e-1)" "unprognostic (2.48e-1)" "unprognostic (2.84e-1)" "unprognostic (1.25e-3)" "unprognostic (2.37e-1)" "unprognostic (3.45e-2)" HCN4 ENSG00000138622 "Hyperpolarization activated cyclic nucleotide gated potassium channel 4" Q9Y3Q4 15 73319859-73368958 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Sodium transport, Transport" "Ion channel, Ligand-gated ion channel, Potassium channel, Sodium channel, Voltage-gated channel" "Brugada syndrome, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "heart muscle: 8.2;testis: 7.0" "Group enriched" "Detected in some" 6 "Early spermatids: 44.7;Late spermatids: 83.4" "Cell type enhanced" "Detected in many" "midbrain-derived inhibitory: 26.4" "Cancer enriched" "Detected in single" 5 "Testicular Germ Cell Tumor (TCGA): 5.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 1.8" "Adrenal gland - Adrenal medulla cells, Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Pituitary gland - Gonadotropes, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA073174 Approved NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 109: Neurons - Neuronal signaling" 5 "HPA073174: " "unprognostic (6.74e-2)" HCRT "OX, PPOX" ENSG00000161610 "Hypocretin neuropeptide precursor" O43612 17 42184060-42185452 "Disease related genes, Human disease related genes, Predicted secreted proteins" Neuropeptide "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1429 "brain: 400.8" "Cell type enhanced" "Detected in some" "Foveolar cells: 4.7;Gastric progenitor cells: 3.8;Neuroendocrine cells: 5.7;Other brain neurons: 21.2;Paneth cells: 3.9" "Cell type enhanced" "Detected in many" "splatter: 6.7" "Not detected" "Not detected" "Region enriched" "Detected in many" 8 "hypothalamus: 901.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in some" 5 "hypothalamus: 93.4" "Region enriched" "Detected in some" 60 "hypothalamus: 146.5" "HPA064801, CAB079778" Enhanced Supported "Secreted to blood" Neuropeptide NA NA "Cluster 32: Basophils - Transcription" "Cluster 36: Brain & Liver - Signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 98: Neurons - Neurotransmission & signaling" 1 "CAB079778: , HPA064801: " HCRTR1 "ORXR1, OX1R, OXR1" ENSG00000121764 "Hypocretin receptor 1" O43613 1 31617686-31632518 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "adrenal gland: 1.0" "Cell type enhanced" "Detected in some" "Adipocytes: 9.8;Cardiomyocytes: 22.2;Epicardial cells: 38.7;Late spermatids: 8.6" "Cell type enhanced" "Detected in some" "CGE interneuron: 4.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adrenal gland - Adrenal medulla cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA014018 Approved NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 54: Non-specific - Transcription" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 2 "HPA014018: " HCRTR2 "ORXR2, OX2R, OXR2" ENSG00000137252 "Hypocretin receptor 2" O43614 6 55106460-55282617 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 17.2;Brain inhibitory neurons: 24.1;Gonadotrophs: 8.5;Other brain neurons: 34.7;Retinal amacrine cells: 22.1" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 120.7;deep-layer corticothalamic and 6b: 132.2;LAMP5-LHX6 and Chandelier: 186.6;lower rhombic lip: 211.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "cervical cancer: 1.0" "Pituitary gland - Gonadotropes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA054516, HPA070481" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 49: Hindbrain - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 109: Neurons - Neuronal signaling" 1 "Plasma membrane" Nucleoplasm "HPA054516: , HPA070481: " HCST "DAP10, DKFZP586C1522, KAP10, PIK3AP" ENSG00000126264 "Hematopoietic cell signal transducer" Q9UBK5 19 35902529-35904377 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 239.0;lymphoid tissue: 112.5" "Cell type enhanced" "Detected in many" "cDC: 395.6;Hofbauer cells: 855.7;Kupffer cells: 165.0;Macrophages: 251.9;Megakaryocytes: 302.9;Monocyte progenitors: 176.5;monocytes: 365.0;Neutrophil progenitors: 171.5;NK-cells: 726.2;pDCs: 273.1;Platelets: 348.5;T-cells: 546.1" "Cell type enriched" "Detected in some" 5 "leukocyte: 211.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 13 "Leukemia: 92.4;lymphoma: 51.9;Myeloma: 35.3" "Adrenal gland - Macrophages, Skeletal muscle - Macrophages, Spleen - T-cells, Thyroid gland - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB034435, HPA063026" Enhanced Uncertain "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 2 "Golgi apparatus, Vesicles, Plasma membrane" "CAB034435: , HPA063026: " "unprognostic (1.95e-1)" "unprognostic (5.51e-3)" "unprognostic (3.31e-2)" "unprognostic (4.01e-2)" "unprognostic (2.48e-2)" "unprognostic (2.52e-1)" "unprognostic (7.34e-2)" "unprognostic (3.10e-1)" "unprognostic (1.96e-2)" "unprognostic (4.71e-2)" "potential prognostic unfavorable (1.55e-4)" "unprognostic (2.52e-1)" "unprognostic (2.02e-1)" "unprognostic (3.19e-1)" "unprognostic (6.11e-2)" "unprognostic (3.39e-2)" "unprognostic (8.00e-2)" "unprognostic (2.22e-1)" "unprognostic (4.37e-1)" "unprognostic (1.44e-1)" "unprognostic (1.87e-1)" "unprognostic (8.27e-2)" "unprognostic (2.84e-1)" "unprognostic (2.41e-1)" "unprognostic (9.97e-2)" "unprognostic (5.46e-2)" "unprognostic (1.79e-3)" "unprognostic (3.59e-1)" "unprognostic (5.64e-3)" "unprognostic (2.77e-1)" "unprognostic (1.26e-1)" HDAC1 "GON-10, HD1, KDAC1, RPD3L1" ENSG00000116478 "Histone deacetylase 1" Q13547 1 32292083-32333635 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005017, HPA029693, CAB068191" Enhanced Enhanced Nucleoplasm NA NA 170000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 662 Nucleoplasm "CAB005017: , CAB068191: , HPA029693: " "unprognostic (4.14e-1)" "unprognostic (1.12e-1)" "unprognostic (1.66e-1)" "unprognostic (2.47e-1)" "unprognostic (1.05e-1)" "unprognostic (1.83e-1)" "unprognostic (4.27e-1)" "unprognostic (2.70e-1)" "unprognostic (1.40e-1)" "unprognostic (2.74e-3)" "unprognostic (1.59e-2)" "unprognostic (1.48e-2)" "unprognostic (4.26e-1)" "potential prognostic unfavorable (2.99e-10)" "unprognostic (1.07e-3)" "unprognostic (4.08e-2)" "unprognostic (5.83e-3)" "unprognostic (2.71e-1)" "unprognostic (1.13e-1)" "unprognostic (1.46e-3)" "unprognostic (5.09e-2)" "unprognostic (8.31e-3)" "unprognostic (1.06e-1)" "unprognostic (1.88e-1)" "unprognostic (1.89e-1)" "unprognostic (3.70e-1)" "unprognostic (1.98e-1)" "unprognostic (1.87e-1)" "unprognostic (3.27e-1)" "unprognostic (4.66e-2)" "unprognostic (1.19e-1)" HDAC10 DKFZP761B039 ENSG00000100429 "Histone deacetylase 10" Q969S8 22 50245183-50251405 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Autophagy, DNA damage, DNA recombination, DNA repair" Hydrolase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019662, CAB045977" Supported Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 20: Non-specific - Transcription regulation" 10 Nucleoplasm "Vesicles, Cytosol" "CAB045977: , HPA019662: " "unprognostic (2.06e-2)" "unprognostic (1.29e-2)" "unprognostic (1.05e-1)" "unprognostic (2.55e-2)" "unprognostic (7.22e-2)" "unprognostic (7.15e-2)" "unprognostic (1.92e-1)" "unprognostic (2.31e-3)" "unprognostic (7.75e-2)" "unprognostic (1.10e-1)" "unprognostic (9.20e-2)" "unprognostic (2.17e-1)" "unprognostic (3.96e-1)" "unprognostic (1.16e-2)" "unprognostic (2.42e-1)" "unprognostic (2.98e-1)" "unprognostic (1.48e-1)" "unprognostic (2.06e-3)" "unprognostic (2.11e-1)" "potential prognostic unfavorable (1.37e-4)" "unprognostic (2.92e-2)" "unprognostic (1.65e-2)" "unprognostic (1.51e-2)" "potential prognostic unfavorable (2.28e-4)" "unprognostic (1.47e-1)" "unprognostic (1.68e-1)" "unprognostic (1.49e-1)" "unprognostic (1.21e-2)" "unprognostic (1.57e-3)" "unprognostic (2.78e-3)" "unprognostic (9.73e-2)" HDAC11 ENSG00000163517 "Histone deacetylase 11" Q96DB2 3 13479724-13506424 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 93.9;testis: 80.4" "Group enriched" "Detected in many" 6 "Early spermatids: 412.8;Late spermatids: 1214.6" "Cell type enhanced" "Detected in all" "oligodendrocyte: 67.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB080427 Supported Nucleoplasm,Cytosol NA NA 180000 "Cluster 33: Non-specific - ATP binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 15 Nucleoplasm Cytosol "CAB080427: " "unprognostic (9.44e-2)" "unprognostic (7.28e-2)" "unprognostic (7.65e-3)" "unprognostic (1.82e-2)" "unprognostic (2.51e-1)" "unprognostic (1.63e-2)" "unprognostic (2.67e-1)" "unprognostic (1.86e-1)" "unprognostic (2.01e-2)" "unprognostic (1.91e-1)" "validated prognostic favorable (6.96e-8)" "validated prognostic favorable (1.50e-4)" "potential prognostic favorable (3.30e-7)" "validated prognostic unfavorable (2.45e-6)" "validated prognostic unfavorable (4.39e-4)" "unprognostic (1.10e-2)" "unprognostic (2.09e-1)" "unprognostic (2.53e-2)" "unprognostic (2.09e-1)" "unprognostic (1.31e-1)" "unprognostic (1.25e-2)" "unprognostic (1.84e-1)" "unprognostic (2.31e-1)" "unprognostic (1.55e-1)" "unprognostic (2.67e-2)" "unprognostic (5.75e-2)" "unprognostic (5.89e-2)" "unprognostic (2.55e-2)" "unprognostic (1.57e-1)" "unprognostic (2.23e-2)" "unprognostic (8.40e-2)" HDAC2 "KDAC2, RPD3, YAF1" ENSG00000196591 "Histone deacetylase 2" Q92769 6 113933028-114011308 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005054, HPA011727" Supported Supported Nucleoplasm NA NA 200000 "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 26: Keratinocytes - Keratinization" 414 Nucleoplasm "CAB005054: , HPA011727: " "unprognostic (5.85e-2)" "potential prognostic unfavorable (2.58e-4)" "unprognostic (4.20e-3)" "unprognostic (7.19e-2)" "unprognostic (9.67e-2)" "unprognostic (1.12e-1)" "unprognostic (4.43e-2)" "unprognostic (9.74e-3)" "unprognostic (2.90e-2)" "potential prognostic unfavorable (2.40e-5)" "potential prognostic favorable (9.82e-6)" "unprognostic (3.25e-2)" "unprognostic (1.49e-2)" "validated prognostic unfavorable (1.81e-11)" "validated prognostic unfavorable (7.88e-5)" "unprognostic (9.66e-3)" "unprognostic (1.37e-3)" "unprognostic (9.83e-2)" "unprognostic (7.22e-2)" "unprognostic (8.21e-2)" "unprognostic (1.07e-1)" "unprognostic (2.46e-1)" "unprognostic (1.96e-2)" "unprognostic (2.95e-1)" "unprognostic (8.92e-2)" "unprognostic (1.85e-1)" "unprognostic (1.09e-1)" "unprognostic (1.01e-1)" "unprognostic (1.67e-1)" "unprognostic (3.04e-1)" "unprognostic (4.25e-3)" HDAC3 "HD3, KDAC3, RPD3, RPD3-2" ENSG00000171720 "Histone deacetylase 3" O15379 5 141620876-141636849 "Enzymes, Essential proteins, FDA approved drug targets, Predicted intracellular proteins" "Biological rhythms, Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005583, HPA052052, CAB072336" Supported Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 7: Non-specific - Transcription" 142 Nucleoplasm "Golgi apparatus, Cytosol" "CAB005583: , CAB072336: , HPA052052: " "unprognostic (6.66e-2)" "unprognostic (1.78e-2)" "unprognostic (4.09e-2)" "unprognostic (1.72e-1)" "potential prognostic favorable (7.04e-4)" "unprognostic (3.86e-1)" "unprognostic (1.68e-1)" "unprognostic (5.21e-2)" "unprognostic (5.09e-2)" "unprognostic (8.59e-3)" "potential prognostic favorable (7.82e-6)" "unprognostic (9.07e-2)" "unprognostic (2.17e-1)" "potential prognostic unfavorable (3.70e-4)" "unprognostic (5.64e-2)" "unprognostic (3.92e-1)" "unprognostic (4.14e-2)" "unprognostic (3.46e-2)" "unprognostic (1.68e-1)" "unprognostic (5.56e-2)" "unprognostic (1.13e-1)" "unprognostic (2.00e-1)" "unprognostic (3.90e-3)" "unprognostic (4.50e-2)" "unprognostic (3.32e-3)" "unprognostic (3.59e-2)" "unprognostic (2.03e-1)" "unprognostic (1.65e-1)" "unprognostic (1.63e-1)" "unprognostic (1.37e-3)" "unprognostic (1.46e-1)" HDAC4 "BDMR, HA6116, HD4, HDAC-4, HDAC-A, HDACA, KIAA0288" ENSG00000068024 "Histone deacetylase 4" P56524 2 239048168-239401654 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "Disease variant, Epilepsy, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 33.2;tongue: 24.9" "Cell type enhanced" "Detected in many" "Myonuclei: 1091.2;Neutrophils: 672.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 32.0;neutrophil: 47.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 47.0" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Minor Salivary Gland - Endothelial cells, Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048723, HPA071448" Approved Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 89 "Nuclear speckles" "Nucleoplasm, Cytosol" "HPA048723: , HPA071448: " "unprognostic (5.13e-2)" "unprognostic (2.60e-1)" "potential prognostic favorable (5.12e-4)" "unprognostic (6.39e-2)" "unprognostic (1.89e-1)" "unprognostic (5.26e-2)" "unprognostic (8.97e-2)" "potential prognostic favorable (2.43e-4)" "unprognostic (1.29e-2)" "unprognostic (5.11e-2)" "unprognostic (6.51e-3)" "unprognostic (1.90e-2)" "unprognostic (2.41e-1)" "potential prognostic unfavorable (3.36e-4)" "unprognostic (1.23e-2)" "unprognostic (9.01e-2)" "unprognostic (2.83e-1)" "unprognostic (7.20e-2)" "unprognostic (1.88e-3)" "potential prognostic unfavorable (1.54e-4)" "unprognostic (4.11e-1)" "unprognostic (1.95e-3)" "unprognostic (6.59e-2)" "unprognostic (3.31e-2)" "unprognostic (8.41e-3)" "unprognostic (1.30e-2)" "unprognostic (9.53e-2)" "unprognostic (4.29e-1)" "unprognostic (5.74e-2)" "unprognostic (1.87e-2)" "unprognostic (6.70e-2)" HDAC5 "FLJ90614, KIAA0600, NY-CO-9" ENSG00000108840 "Histone deacetylase 5" Q9UQL6 17 44076746-44123702 "Cancer-related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 363.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019400, HPA030991, HPA076420" Approved Supported "Nuclear speckles,Golgi apparatus,Cytosol" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 65 "Nuclear speckles" "Golgi apparatus, Cytosol" "CAB019400: , HPA030991: , HPA076420: " "unprognostic (3.24e-1)" "unprognostic (1.83e-1)" "unprognostic (1.52e-1)" "unprognostic (1.85e-1)" "unprognostic (4.09e-2)" "unprognostic (3.12e-2)" "unprognostic (1.10e-1)" "potential prognostic favorable (5.15e-4)" "unprognostic (1.47e-1)" "unprognostic (3.37e-1)" "validated prognostic favorable (9.67e-6)" "validated prognostic favorable (1.21e-4)" "unprognostic (2.29e-1)" "potential prognostic unfavorable (4.86e-4)" "unprognostic (6.60e-3)" "unprognostic (4.29e-2)" "unprognostic (1.09e-1)" "unprognostic (1.15e-1)" "unprognostic (9.56e-2)" "unprognostic (6.01e-3)" "unprognostic (1.75e-2)" "unprognostic (1.47e-2)" "unprognostic (1.95e-1)" "unprognostic (2.29e-1)" "unprognostic (4.42e-2)" "unprognostic (5.56e-2)" "unprognostic (2.86e-1)" "unprognostic (2.66e-2)" "unprognostic (4.13e-2)" "unprognostic (1.36e-1)" "unprognostic (5.56e-2)" HDAC6 "FLJ16239, HD6, JM21, KIAA0901, PPP1R90" ENSG00000094631 "Histone deacetylase 6" Q9UBN7 X 48801377-48824982 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "Autophagy, Transcription, Transcription regulation, Ubl conjugation pathway" "Actin-binding, Chromatin regulator, Hydrolase, Repressor, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early primary spermatocytes: 125.4;Proximal tubule cells: 77.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003714, CAB004236, HPA026321" Supported Supported "Nucleoplasm,Centrosome,Basal body,Cytosol" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 36: Non-specific - mRNA processing" "Cluster 3: Early primary spermatocytes - Early meiosis" 205 "Centrosome, Basal body, Cytosol" Nucleoplasm "CAB004236: , HPA003714: , HPA026321: " "potential prognostic favorable (9.11e-4)" "unprognostic (1.12e-2)" "unprognostic (1.12e-1)" "unprognostic (2.94e-3)" "unprognostic (3.35e-1)" "unprognostic (1.17e-1)" "unprognostic (9.35e-2)" "unprognostic (3.60e-3)" "unprognostic (2.08e-2)" "unprognostic (9.15e-3)" "potential prognostic favorable (1.55e-5)" "unprognostic (2.56e-2)" "potential prognostic favorable (8.12e-5)" "unprognostic (6.06e-2)" "unprognostic (1.21e-2)" "unprognostic (5.30e-2)" "unprognostic (4.73e-2)" "unprognostic (1.61e-1)" "unprognostic (3.23e-3)" "unprognostic (9.08e-2)" "unprognostic (1.20e-2)" "unprognostic (6.54e-2)" "potential prognostic unfavorable (7.50e-4)" "unprognostic (1.69e-1)" "unprognostic (2.56e-1)" "unprognostic (2.57e-1)" "unprognostic (3.52e-1)" "unprognostic (2.38e-1)" "unprognostic (4.07e-2)" "unprognostic (6.43e-2)" "unprognostic (1.96e-2)" HDAC7 "DKFZP586J0917, HDAC7A" ENSG00000061273 "Histone deacetylase 7" Q8WUI4 12 47782722-47833132 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cell type enhanced" "Detected in all" "endothelial cell: 137.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "neutrophil: 6.5" "Lineage enriched" "Detected in many" 4 "granulocytes: 6.5" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004775, CAB080431" Enhanced Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 49: Non-specific - Transcription" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 15: Kidney cancer - Membrane components" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 39 Cytosol "CAB080431: , HPA004775: " "unprognostic (2.18e-3)" "unprognostic (1.27e-1)" "unprognostic (8.90e-2)" "unprognostic (1.09e-3)" "unprognostic (9.24e-2)" "unprognostic (9.69e-2)" "unprognostic (1.86e-2)" "unprognostic (5.19e-3)" "unprognostic (3.18e-2)" "unprognostic (7.12e-2)" "potential prognostic favorable (8.09e-4)" "unprognostic (2.53e-2)" "unprognostic (4.67e-1)" "unprognostic (9.36e-3)" "unprognostic (1.33e-3)" "unprognostic (3.34e-1)" "potential prognostic unfavorable (9.03e-4)" "unprognostic (1.80e-2)" "unprognostic (9.15e-2)" "unprognostic (4.11e-2)" "unprognostic (3.89e-2)" "unprognostic (1.41e-2)" "unprognostic (2.49e-3)" "unprognostic (1.60e-1)" "unprognostic (1.64e-1)" "unprognostic (1.58e-2)" "unprognostic (1.96e-1)" "unprognostic (1.30e-1)" "unprognostic (1.88e-1)" "unprognostic (4.97e-2)" "unprognostic (2.82e-1)" HDAC8 "HDACL1, KDAC8, MRXS6, RPD3, WTS" ENSG00000147099 "Histone deacetylase 8" Q9BY41 X 72329516-72573101 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "Disease variant, FDA approved drug targets, Intellectual disability, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 191.4;Bergmann glia: 193.0;Brain excitatory neurons: 219.3;Brain inhibitory neurons: 200.7;Choroid plexus epithelial cells: 387.9;Distal convoluted tubule cells: 287.7;Ependymal cells: 159.3;Loop of henle epithelial cells: 202.5;Microglia: 252.7;Oligodendrocyte progenitor cells: 227.2;Oligodendrocytes: 190.5;Other brain neurons: 190.0;Papillary tip epithelial cells: 169.6;Podocytes: 204.7;Proximal tubule cells: 236.4;Renal collecting duct intercalated cells: 216.3;Renal collecting duct principal cells: 201.8;Renal connecting tubule cells: 261.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048560 Supported NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 76: Non-specific - Metabolism" "Cluster 9: Non-specific - Receptor signaling" "Cluster 36: Non-specific - mRNA processing" "Cluster 102: Non-specific - Mixed function" 1 "HPA048560: " "unprognostic (1.10e-1)" "unprognostic (1.93e-1)" "unprognostic (8.48e-2)" "unprognostic (1.17e-1)" "unprognostic (2.83e-1)" "unprognostic (2.21e-1)" "unprognostic (1.61e-1)" "unprognostic (3.09e-3)" "unprognostic (1.08e-1)" "potential prognostic unfavorable (3.62e-6)" "unprognostic (1.65e-1)" "unprognostic (2.90e-3)" "unprognostic (1.11e-1)" "unprognostic (1.56e-2)" "unprognostic (9.06e-2)" "unprognostic (8.29e-2)" "unprognostic (6.83e-3)" "unprognostic (3.71e-2)" "unprognostic (8.79e-2)" "unprognostic (1.16e-1)" "unprognostic (3.97e-2)" "unprognostic (2.84e-2)" "unprognostic (8.02e-3)" "unprognostic (3.27e-2)" "unprognostic (3.61e-2)" "unprognostic (2.27e-2)" "unprognostic (7.77e-3)" "unprognostic (1.76e-2)" "unprognostic (2.43e-1)" "unprognostic (2.12e-2)" "unprognostic (6.88e-3)" HDAC9 "HD7, HDAC, HDAC7B, KIAA0744, MITR" ENSG00000048052 "Histone deacetylase 9" Q9UKV0 7 18086949-19002416 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 2648.6;cDC: 1768.4;Choroid plexus epithelial cells: 4756.6;Corticotrophs: 1277.6;Microglia: 1354.3;Retinal ganglion cells: 1031.4;Thyrotrophs: 1737.3" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 3812.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 73.7" "Group enriched" "Detected in all" 9 "B-cells: 53.2;dendritic cells: 73.7;monocytes: 24.3" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Prostate - Smooth muscle cells, Stomach - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028926 Uncertain Approved "Nucleoplasm,Mitotic chromosome" Yes NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 23: Choroid plexus - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 19 Nucleoplasm "Mitotic chromosome" "HPA028926: " "unprognostic (1.84e-1)" "unprognostic (3.36e-3)" "unprognostic (5.14e-2)" "unprognostic (2.68e-1)" "unprognostic (2.83e-1)" "unprognostic (2.48e-1)" "unprognostic (4.22e-1)" "unprognostic (9.82e-3)" "unprognostic (5.46e-2)" "unprognostic (8.49e-2)" "potential prognostic favorable (1.07e-4)" "unprognostic (2.04e-2)" "unprognostic (2.05e-1)" "unprognostic (4.47e-1)" "unprognostic (1.40e-1)" "unprognostic (1.93e-1)" "unprognostic (9.46e-2)" "unprognostic (1.18e-2)" "unprognostic (3.73e-1)" "unprognostic (1.86e-1)" "unprognostic (2.26e-1)" "unprognostic (1.77e-1)" "unprognostic (9.34e-2)" "unprognostic (2.68e-2)" "unprognostic (2.40e-2)" "unprognostic (1.30e-1)" "unprognostic (7.78e-2)" "unprognostic (5.11e-2)" "unprognostic (2.18e-1)" "unprognostic (7.01e-2)" HDC ENSG00000140287 "Histidine decarboxylase" P19113 15 50241947-50265965 "Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Catecholamine biosynthesis" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 42.0;epididymis: 43.4" "Cell type enhanced" "Detected in some" "Epididymal principal cells: 50.2;Mast cells: 471.4;Neuroendocrine cells: 100.1;Oocytes: 142.8;Other brain neurons: 217.5" "Cell type enhanced" "Detected in many" "splatter: 16.5" "Group enriched" "Detected in some" 5 "Breast Invasive Carcinoma (TCGA): 5.8;Testicular Germ Cell Tumor (TCGA): 3.0" "Region enriched" "Detected in many" 6 "hypothalamus: 227.7" "Immune cell enriched" "Detected in single" 2147 "basophil: 686.7" "Lineage enriched" "Detected in single" 2147 "granulocytes: 686.7" "Group enriched" "Detected in some" 5 "Leukemia: 41.3;Rhabdoid: 14.0" "Colon - Mast cells, Lung - Mast cells, Skeletal muscle - Fibroblasts" "Region enriched" "Detected in many" 5 "hypothalamus: 43.9" "Group enriched" "Detected in many" 10 "hypothalamus: 21.6;midbrain: 5.6" HPA038891 Enhanced Approved "Nuclear bodies" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 22: Epididymis - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 49: HMC-1 - Innate immune response" "Cluster 58: Mast cells - Allergic inflammatory responses" 1 "Nuclear bodies" "HPA038891: " "unprognostic (4.97e-2)" "unprognostic (1.61e-1)" "unprognostic (3.33e-3)" "unprognostic (2.49e-1)" "unprognostic (5.15e-2)" "unprognostic (2.48e-2)" "unprognostic (2.35e-2)" "unprognostic (9.08e-2)" HDDC2 "C6orf74, CGI-130, dJ167O5.2" ENSG00000111906 "HD domain containing 2" Q7Z4H3 6 125219962-125302078 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 156.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 334.3;Myonuclei: 265.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035677 Approved Approved Nucleoplasm,Nucleoli NA NA 13000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 55: Myocytes - Oxidative muscle function" 3 Nucleoli Nucleoplasm "HPA035677: " "unprognostic (7.89e-2)" "unprognostic (1.84e-2)" "unprognostic (3.98e-2)" "unprognostic (3.02e-1)" "unprognostic (1.91e-1)" "unprognostic (8.28e-2)" "unprognostic (4.36e-2)" "unprognostic (1.43e-1)" "unprognostic (1.76e-3)" "unprognostic (2.98e-2)" "potential prognostic favorable (1.03e-4)" "unprognostic (1.43e-2)" "unprognostic (8.41e-2)" "potential prognostic unfavorable (7.11e-5)" "unprognostic (2.53e-3)" "unprognostic (2.29e-2)" "unprognostic (1.93e-1)" "unprognostic (5.83e-2)" "unprognostic (1.14e-1)" "unprognostic (5.83e-2)" "unprognostic (7.19e-2)" "unprognostic (7.90e-2)" "unprognostic (1.81e-1)" "unprognostic (5.77e-3)" "unprognostic (2.09e-1)" "unprognostic (3.34e-2)" "unprognostic (1.09e-2)" "unprognostic (1.52e-1)" "unprognostic (7.45e-2)" "unprognostic (5.80e-3)" "unprognostic (2.74e-1)" HDDC3 "MESH1, MGC45386" ENSG00000184508 "HD domain containing 3" Q8N4P3 15 90929968-90935196 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Megakaryocytes: 74.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040895 Approved Approved Nucleoplasm,Cytosol No No 6200 "Cluster 13: Non-specific - Mitochondria" "Cluster 70: Non-specific - Protein processing" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 58: Non-specific - Nuclear processes" "Cluster 97: Non-specific - Cellular respiration" 8 "Nucleoplasm, Cytosol" "HPA040895: " "unprognostic (5.14e-2)" "unprognostic (8.95e-2)" "unprognostic (1.40e-1)" "unprognostic (7.85e-2)" "unprognostic (2.35e-1)" "unprognostic (7.00e-2)" "unprognostic (1.18e-2)" "unprognostic (4.57e-2)" "potential prognostic unfavorable (2.99e-4)" "unprognostic (7.53e-2)" "unprognostic (5.34e-3)" "unprognostic (4.36e-1)" "unprognostic (3.22e-3)" "unprognostic (3.44e-1)" "unprognostic (5.97e-3)" "unprognostic (1.95e-2)" "unprognostic (2.69e-1)" "unprognostic (1.88e-1)" "unprognostic (1.62e-1)" "unprognostic (6.86e-3)" "unprognostic (2.05e-1)" "unprognostic (1.08e-1)" "unprognostic (8.54e-2)" "unprognostic (1.35e-2)" "unprognostic (2.18e-1)" "unprognostic (4.85e-2)" "unprognostic (2.83e-2)" "unprognostic (1.03e-1)" "unprognostic (3.15e-1)" "unprognostic (8.85e-2)" "unprognostic (6.13e-2)" HDGF HMG1L2 ENSG00000143321 "Heparin binding growth factor" P51858 1 156742109-156766925 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Transcription, Transcription regulation" "DNA-binding, Growth factor, Heparin-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 347.7;Gastric progenitor cells: 302.5;Megakaryocytes: 408.0" "Cell type enhanced" "Detected in all" "ependymal cell: 99.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026035, HPA048728, HPA053422" Enhanced Enhanced Nucleoplasm "Secreted to blood" "Growth factor" NA NA 1300000 "Cluster 29: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 27 Nucleoplasm "CAB026035: , HPA048728: , HPA053422: " "unprognostic (2.54e-1)" "unprognostic (3.49e-1)" "unprognostic (1.06e-1)" "unprognostic (1.61e-3)" "unprognostic (2.64e-1)" "unprognostic (4.15e-2)" "unprognostic (9.62e-2)" "unprognostic (1.08e-2)" "unprognostic (7.51e-2)" "unprognostic (1.19e-2)" "unprognostic (2.47e-2)" "unprognostic (4.12e-2)" "unprognostic (1.31e-2)" "validated prognostic unfavorable (2.91e-8)" "validated prognostic unfavorable (2.85e-4)" "unprognostic (1.24e-3)" "unprognostic (7.79e-3)" "unprognostic (2.87e-2)" "unprognostic (1.18e-1)" "unprognostic (1.16e-2)" "unprognostic (4.06e-1)" "unprognostic (1.13e-2)" "unprognostic (6.42e-2)" "unprognostic (4.78e-2)" "unprognostic (6.57e-2)" "unprognostic (3.66e-1)" "unprognostic (1.42e-1)" "unprognostic (2.97e-2)" "unprognostic (2.39e-1)" "unprognostic (7.41e-2)" "unprognostic (1.15e-1)" HDGFL1 "dJ309H15.1, Hdgfrp1, HRP-1, PWWP1" ENSG00000112273 "HDGF like 1" Q5TGJ6 6 22569566-22571666 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 212 "testis: 87.5" "Cell type enriched" "Detected in single" 4 "Late primary spermatocytes: 3.9" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 48 "Testicular Germ Cell Tumor (TCGA): 33.0" "Region enhanced" "Detected in single" "cerebral cortex: 1.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "Gallbladder cancer: 1.1" "Pituitary gland - Lactotropes, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045679, HPA063707" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 53: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" "Nucleoplasm, Nucleoli fibrillar center" "HPA045679: , HPA063707: " "unprognostic (1.12e-1)" HDGFL2 "Hdgfrp2, HRP2" ENSG00000167674 "HDGF like 2" Q7Z4V5 19 4472297-4502208 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Myogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 85.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 5.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042559, HPA044208" Enhanced Supported Nucleoplasm,Mitochondria,Cytosol No No "Cluster 43: Non-specific - Transcription & Translation" "Cluster 24: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 18 Nucleoplasm "Mitochondria, Cytosol" "HPA042559: , HPA044208: " "unprognostic (8.41e-3)" "unprognostic (1.14e-1)" "unprognostic (4.77e-2)" "unprognostic (1.99e-1)" "unprognostic (5.44e-2)" "unprognostic (5.06e-2)" "unprognostic (2.20e-2)" "unprognostic (4.73e-2)" "unprognostic (6.63e-2)" "unprognostic (2.26e-1)" "unprognostic (1.03e-1)" "unprognostic (1.22e-1)" "potential prognostic unfavorable (4.56e-4)" "unprognostic (2.49e-1)" "unprognostic (2.67e-2)" "unprognostic (3.36e-1)" "unprognostic (5.18e-2)" "unprognostic (2.38e-1)" "unprognostic (1.20e-1)" "potential prognostic favorable (6.01e-5)" "unprognostic (8.83e-2)" "unprognostic (2.26e-2)" "unprognostic (3.01e-1)" "unprognostic (7.00e-2)" "unprognostic (1.46e-1)" "unprognostic (8.17e-2)" "unprognostic (1.29e-1)" "unprognostic (2.15e-1)" "unprognostic (1.22e-2)" HDGFL3 "Hdgfrp3, HRP-3" ENSG00000166503 "HDGF like 3" Q9Y3E1 15 83112738-83207823 "Predicted intracellular proteins" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 221.3;Vascular endothelial cells: 227.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 1.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Adrenal gland - Fibroblasts, Liver - Vascular endothelial cells, Skin - Endothelial cells, Spleen - Endothelial cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040719 Approved Supported Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 73: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 1 Nucleoplasm "HPA040719: " "unprognostic (1.74e-3)" "unprognostic (6.66e-3)" "unprognostic (3.06e-1)" "unprognostic (5.23e-3)" "unprognostic (1.06e-1)" "unprognostic (1.76e-1)" "potential prognostic favorable (4.62e-4)" "unprognostic (2.22e-2)" "unprognostic (6.77e-2)" "unprognostic (2.00e-1)" "unprognostic (5.11e-2)" "unprognostic (2.76e-1)" "potential prognostic unfavorable (4.52e-5)" "unprognostic (2.50e-2)" "unprognostic (2.98e-2)" "unprognostic (1.65e-1)" "unprognostic (2.20e-1)" "unprognostic (1.62e-1)" "potential prognostic favorable (1.12e-4)" "unprognostic (3.47e-2)" "unprognostic (1.88e-2)" "unprognostic (7.89e-2)" "unprognostic (5.63e-2)" "unprognostic (4.28e-3)" "unprognostic (1.21e-3)" "unprognostic (1.57e-1)" "unprognostic (6.59e-2)" "unprognostic (4.47e-2)" HDHD2 DKFZP564D1378 ENSG00000167220 "Haloacid dehalogenase like hydrolase domain containing 2" Q9H0R4 18 47107408-47150500 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Megakaryocytes: 92.7;Parietal cells: 65.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040697, CAB045978, HPA059818" Approved Approved Vesicles NA NA 130000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 76: Non-specific - Metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 97: Non-specific - Cellular respiration" 2 Vesicles "CAB045978: , HPA040697: , HPA059818: " "unprognostic (2.19e-1)" "unprognostic (1.73e-1)" "unprognostic (2.54e-2)" "unprognostic (2.27e-1)" "unprognostic (2.60e-3)" "unprognostic (1.22e-1)" "unprognostic (1.36e-1)" "unprognostic (1.96e-2)" "unprognostic (2.09e-1)" "unprognostic (2.04e-1)" "potential prognostic favorable (2.28e-4)" "unprognostic (2.37e-3)" "unprognostic (3.15e-3)" "unprognostic (8.61e-2)" "unprognostic (3.49e-2)" "unprognostic (1.74e-1)" "unprognostic (2.17e-2)" "unprognostic (2.26e-1)" "unprognostic (1.06e-1)" "unprognostic (3.02e-2)" "unprognostic (2.18e-1)" "unprognostic (5.06e-3)" "unprognostic (2.81e-1)" "unprognostic (5.71e-2)" "unprognostic (1.08e-2)" "unprognostic (8.55e-2)" "unprognostic (4.98e-2)" "unprognostic (4.80e-2)" "unprognostic (2.72e-2)" "unprognostic (1.70e-1)" "unprognostic (4.18e-2)" HDHD3 "C9orf158, MGC12904" ENSG00000119431 "Haloacid dehalogenase like hydrolase domain containing 3" Q9BSH5 9 113373419-113376986 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 151.0;liver: 123.4" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 305.5;Colonocytes: 299.8;Enterocytes: 536.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020427, HPA024158, HPA024585" Enhanced Enhanced Nucleoli,Vesicles NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 33: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 17 Nucleoli Vesicles "HPA020427: , HPA024158: , HPA024585: " "unprognostic (8.03e-2)" "unprognostic (4.02e-1)" "unprognostic (1.97e-1)" "unprognostic (2.86e-2)" "unprognostic (6.04e-3)" "unprognostic (1.36e-1)" "unprognostic (2.29e-3)" "potential prognostic unfavorable (1.94e-5)" "unprognostic (2.40e-2)" "unprognostic (1.34e-1)" "potential prognostic favorable (5.20e-6)" "unprognostic (4.46e-2)" "potential prognostic favorable (6.00e-5)" "unprognostic (5.88e-2)" "unprognostic (6.38e-2)" "unprognostic (1.76e-1)" "unprognostic (8.87e-2)" "unprognostic (9.15e-2)" "unprognostic (1.40e-2)" "unprognostic (2.25e-1)" "unprognostic (7.58e-2)" "unprognostic (5.78e-2)" "unprognostic (4.45e-2)" "unprognostic (6.48e-2)" "unprognostic (9.14e-2)" "unprognostic (5.64e-3)" "unprognostic (3.56e-2)" "unprognostic (1.23e-1)" "unprognostic (4.28e-1)" "unprognostic (1.19e-1)" "unprognostic (3.58e-3)" HDHD5 CECR5 ENSG00000069998 "Haloacid dehalogenase like hydrolase domain containing 5" Q9BXW7 22 17137511-17165287 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 94.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005548, HPA076973" Approved Enhanced Mitochondria NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cellular respiration" "Cluster 27: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 97: Non-specific - Cellular respiration" 2 Mitochondria "HPA005548: , HPA076973: " "unprognostic (6.40e-2)" "unprognostic (1.97e-3)" "unprognostic (8.66e-2)" "unprognostic (6.76e-3)" "unprognostic (8.35e-3)" "unprognostic (1.20e-1)" "unprognostic (3.01e-3)" "unprognostic (1.40e-2)" "unprognostic (3.50e-2)" "potential prognostic favorable (2.76e-5)" "unprognostic (4.93e-2)" "potential prognostic favorable (1.41e-4)" "potential prognostic unfavorable (6.79e-4)" "unprognostic (9.46e-2)" "unprognostic (3.61e-2)" "unprognostic (6.02e-2)" "unprognostic (2.58e-2)" "unprognostic (8.97e-2)" "unprognostic (1.73e-1)" "unprognostic (2.87e-1)" "unprognostic (4.49e-1)" "unprognostic (2.13e-2)" "unprognostic (3.37e-3)" "unprognostic (1.21e-2)" "unprognostic (9.36e-2)" "unprognostic (4.53e-2)" "unprognostic (1.46e-1)" "unprognostic (4.59e-2)" "unprognostic (3.96e-2)" HDLBP "HBP, VGL" ENSG00000115677 "High density lipoprotein binding protein" Q00341 2 241227264-241317061 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epididymal principal cells: 735.3;Late spermatids: 710.9;Pancreatic acinar cells: 733.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Stomach - Chief cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004189, CAB026457, HPA070707" Enhanced Supported "Nuclear bodies,Endoplasmic reticulum" NA NA 53000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 60: Stomach - Digestion" "Cluster 36: Choroid plexus - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 44: Plasma cells - Antibody production & secretion" 73 "Endoplasmic reticulum" "Nuclear bodies" "CAB026457: , HPA004189: , HPA070707: " "unprognostic (8.27e-2)" "unprognostic (3.55e-2)" "unprognostic (3.02e-3)" "unprognostic (3.21e-3)" "unprognostic (1.41e-1)" "unprognostic (2.21e-1)" "unprognostic (2.85e-1)" "unprognostic (1.28e-2)" "unprognostic (2.52e-1)" "unprognostic (5.56e-2)" "potential prognostic favorable (9.79e-4)" "unprognostic (2.09e-1)" "unprognostic (8.56e-3)" "validated prognostic unfavorable (4.75e-4)" "validated prognostic unfavorable (9.63e-4)" "unprognostic (2.05e-2)" "unprognostic (1.29e-2)" "unprognostic (1.50e-2)" "unprognostic (7.32e-2)" "unprognostic (4.79e-2)" "unprognostic (4.61e-2)" "potential prognostic unfavorable (6.52e-4)" "unprognostic (9.84e-2)" "unprognostic (2.62e-1)" "unprognostic (1.74e-1)" "unprognostic (2.22e-1)" "unprognostic (1.80e-1)" "unprognostic (7.03e-2)" "unprognostic (7.73e-2)" "unprognostic (6.81e-3)" "unprognostic (4.33e-1)" HDX "CXorf43, FLJ30678" ENSG00000165259 "Highly divergent homeobox" Q7Z353 X 84317874-84502479 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Epididymal basal cells: 174.0;Urothelial cells: 124.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Skin - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA047189 Uncertain Approved Cytosol NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 65: Brain - Transcription" "Cluster 2: Neurons - Nucleosome" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 103: Non-specific - Basic cellular processes" 12 Cytosol "HPA047189: " "unprognostic (7.99e-2)" "unprognostic (8.70e-2)" "unprognostic (5.05e-2)" "unprognostic (9.44e-2)" "unprognostic (2.77e-3)" "potential prognostic favorable (1.74e-4)" "unprognostic (2.13e-2)" "unprognostic (1.31e-1)" "unprognostic (9.18e-2)" "unprognostic (3.70e-2)" "unprognostic (4.60e-2)" "unprognostic (2.92e-2)" "unprognostic (6.50e-2)" "unprognostic (2.09e-1)" "unprognostic (2.38e-3)" HEATR1 "BAP28, FLJ10359, UTP10" ENSG00000119285 "HEAT repeat containing 1" Q9H583 1 236549005-236604516 "Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing, Transcription, Transcription regulation" Ribonucleoprotein "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epicardial cells: 152.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046917, HPA062200" Approved Enhanced "Nucleoli fibrillar center,Mitochondria" NA NA 15000 "Cluster 24: Non-specific - Transcription" "Cluster 39: Testis - Nuclear processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 40 "Nucleoli fibrillar center" Mitochondria "HPA046917: , HPA062200: " "unprognostic (3.58e-1)" "unprognostic (1.79e-1)" "unprognostic (2.89e-1)" "potential prognostic unfavorable (7.73e-4)" "unprognostic (1.12e-1)" "unprognostic (1.44e-1)" "unprognostic (5.27e-2)" "unprognostic (9.94e-2)" "unprognostic (1.57e-1)" "unprognostic (1.78e-3)" "unprognostic (2.62e-2)" "unprognostic (1.78e-2)" "potential prognostic unfavorable (5.07e-5)" "potential prognostic unfavorable (3.83e-4)" "unprognostic (4.81e-2)" "unprognostic (1.03e-2)" "unprognostic (8.14e-3)" "unprognostic (1.77e-1)" "unprognostic (2.08e-1)" "unprognostic (2.13e-1)" "unprognostic (2.91e-1)" "unprognostic (3.41e-3)" "unprognostic (6.12e-2)" "unprognostic (7.61e-2)" "potential prognostic favorable (5.05e-4)" "unprognostic (2.73e-2)" "unprognostic (4.78e-2)" "unprognostic (2.66e-1)" "unprognostic (1.64e-1)" "unprognostic (7.34e-3)" "unprognostic (4.85e-2)" HEATR3 FLJ20718 ENSG00000155393 "HEAT repeat containing 3" Q7Z4Q2 16 50065967-50107272 "Plasma proteins, Predicted intracellular proteins" "Erythrocyte maturation, Ribosome biogenesis" "Diamond-Blackfan anemia, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Macrophages: 57.1;monocytes: 63.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041990, HPA058579" Uncertain Approved Nucleoplasm,Cytosol Yes No "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 63 Nucleoplasm Cytosol "HPA041990: , HPA058579: " "unprognostic (4.13e-2)" "unprognostic (1.04e-2)" "unprognostic (3.75e-1)" "potential prognostic unfavorable (7.65e-4)" "unprognostic (5.71e-2)" "unprognostic (2.85e-3)" "unprognostic (6.27e-2)" "unprognostic (1.01e-2)" "unprognostic (9.41e-3)" "unprognostic (9.79e-3)" "unprognostic (1.65e-2)" "unprognostic (2.84e-3)" "unprognostic (1.48e-2)" "potential prognostic unfavorable (1.60e-4)" "unprognostic (4.76e-2)" "unprognostic (1.45e-1)" "unprognostic (1.16e-1)" "unprognostic (1.01e-1)" "unprognostic (4.23e-2)" "unprognostic (2.07e-1)" "unprognostic (4.02e-2)" "unprognostic (2.06e-1)" "unprognostic (6.26e-3)" "unprognostic (1.22e-1)" "potential prognostic favorable (5.34e-4)" "unprognostic (9.65e-2)" "unprognostic (3.35e-3)" "unprognostic (9.78e-2)" "unprognostic (4.35e-1)" "unprognostic (3.04e-1)" "unprognostic (5.35e-3)" HEATR4 MGC48595 ENSG00000187105 "HEAT repeat containing 4" Q86WZ0 14 73478484-73558947 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 10.7" "Cell type enhanced" "Detected in many" "Adipocytes: 66.2;Cardiomyocytes: 141.9;Early spermatids: 157.7;Late primary spermatocytes: 164.6;Late spermatids: 104.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Liver - Hepatocytes, Skin - Sebaceous gland cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA003642, HPA079348" Enhanced Approved Vesicles NA NA "Cluster 47: Testis - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 59: Leukemia - T-cell receptor" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" Vesicles "HPA003642: , HPA079348: " "unprognostic (6.19e-2)" "unprognostic (3.70e-1)" "unprognostic (4.51e-3)" "unprognostic (3.95e-3)" "unprognostic (2.51e-2)" "unprognostic (7.19e-2)" "unprognostic (2.18e-1)" "unprognostic (1.56e-1)" "unprognostic (3.80e-2)" "unprognostic (6.82e-2)" "unprognostic (8.14e-3)" "unprognostic (5.39e-1)" "unprognostic (3.54e-1)" HEATR5A "C14orf125, DKFZP434I1735, p200b" ENSG00000129493 "HEAT repeat containing 5A" Q86XA9 14 31291788-31420550 "Essential proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ependymal cells: 172.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 121.1" "Lineage enriched" "Detected in all" 7 "granulocytes: 121.1" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049539 Uncertain NA NA "Cluster 41: Basophils - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 49: Hindbrain - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 7: Non-specific - Transcription" "HPA049539: " "unprognostic (1.42e-1)" "unprognostic (1.81e-1)" "unprognostic (1.75e-1)" "unprognostic (4.83e-1)" "unprognostic (3.56e-1)" "unprognostic (6.66e-2)" "unprognostic (4.87e-2)" "unprognostic (1.04e-1)" "unprognostic (2.06e-1)" "unprognostic (2.19e-3)" "unprognostic (1.14e-3)" "unprognostic (9.65e-2)" "unprognostic (1.08e-1)" "potential prognostic unfavorable (5.83e-5)" "unprognostic (2.32e-1)" "unprognostic (3.61e-1)" "unprognostic (2.43e-1)" "unprognostic (1.06e-1)" "unprognostic (1.03e-1)" "unprognostic (7.97e-3)" "unprognostic (1.58e-2)" "potential prognostic unfavorable (6.99e-4)" "unprognostic (7.08e-2)" "unprognostic (9.99e-2)" "unprognostic (1.48e-2)" "unprognostic (2.63e-1)" "unprognostic (5.39e-2)" "unprognostic (1.10e-1)" "unprognostic (2.86e-2)" "unprognostic (4.49e-3)" "unprognostic (7.99e-2)" HEATR5B "DKFZp686P15184, KIAA1414, p200, p200a" ENSG00000008869 "HEAT repeat containing 5B" Q9P2D3 2 36968383-37084372 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036369, HPA042025" Approved Supported "Nucleoplasm,Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 32: Basophils - Transcription" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 9: Non-specific - Receptor signaling" "Cluster 55: Lymphoma - Immune response" "Cluster 7: Non-specific - Transcription" 12 "Golgi apparatus, Vesicles" "Nucleoplasm, Cytosol" "HPA036369: , HPA042025: " "unprognostic (3.75e-1)" "unprognostic (4.87e-2)" "unprognostic (7.17e-2)" "unprognostic (3.35e-2)" "unprognostic (1.12e-1)" "unprognostic (2.00e-1)" "unprognostic (1.33e-1)" "unprognostic (9.30e-3)" "unprognostic (1.46e-1)" "unprognostic (1.80e-3)" "potential prognostic favorable (1.23e-4)" "unprognostic (2.13e-2)" "unprognostic (3.78e-2)" "unprognostic (3.02e-2)" "unprognostic (2.27e-1)" "unprognostic (2.35e-2)" "unprognostic (2.32e-1)" "unprognostic (3.13e-2)" "unprognostic (1.01e-1)" "unprognostic (8.78e-2)" "unprognostic (6.45e-2)" "unprognostic (2.33e-2)" "unprognostic (2.61e-2)" "unprognostic (6.61e-2)" "unprognostic (6.91e-3)" "unprognostic (2.52e-1)" "unprognostic (1.02e-1)" "unprognostic (5.95e-2)" "unprognostic (3.05e-1)" "unprognostic (2.43e-2)" "unprognostic (7.87e-2)" HEATR6 "ABC1, FLJ22087" ENSG00000068097 "HEAT repeat containing 6" Q6AI08 17 60041008-60078922 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030789, HPA062157" Uncertain Approved Mitochondria NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 30: White matter - Myelination" "Cluster 27: Breast cancer - Unknown function" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 21 Mitochondria "HPA030789: , HPA062157: " "unprognostic (9.24e-2)" "unprognostic (8.58e-2)" "unprognostic (4.63e-1)" "unprognostic (3.04e-3)" "unprognostic (1.08e-2)" "unprognostic (5.39e-2)" "unprognostic (8.35e-2)" "unprognostic (1.01e-1)" "unprognostic (1.36e-1)" "unprognostic (1.05e-1)" "unprognostic (4.84e-2)" "unprognostic (1.42e-1)" "unprognostic (2.80e-1)" "potential prognostic unfavorable (1.93e-4)" "unprognostic (7.48e-2)" "unprognostic (1.66e-1)" "unprognostic (3.02e-2)" "unprognostic (1.31e-1)" "unprognostic (1.82e-2)" "unprognostic (2.26e-1)" "unprognostic (4.85e-2)" "unprognostic (1.36e-3)" "unprognostic (7.14e-3)" "unprognostic (8.69e-2)" "unprognostic (8.44e-2)" "unprognostic (1.17e-1)" "unprognostic (5.06e-2)" "unprognostic (6.66e-2)" "unprognostic (3.58e-1)" "unprognostic (2.38e-1)" "unprognostic (4.26e-2)" HEATR9 "C17orf66, FLJ32830" ENSG00000270379 "HEAT repeat containing 9" A2RTY3 17 35854946-35868891 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 21 "testis: 9.5" "Group enriched" "Detected in some" 4 "Early spermatids: 7.9;Late primary spermatocytes: 4.4;Late spermatids: 4.6" "Cell type enhanced" "Detected in many" "hippocampal dentate gyrus: 5.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Kidney - T-cells, Prostate - T-cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA023129 Uncertain NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 98: Neurons - Neurotransmission & signaling" 1 "HPA023129: " HEBP1 "HBP, HEBP" ENSG00000013583 "Heme binding protein 1" Q9NRV9 12 12974870-13000265 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 186.8;Enterocytes: 747.5;Erythrocyte progenitors: 269.1;Esophageal apical cells: 210.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Fibroblasts, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056417, HPA075277" Approved Approved Nucleoplasm,Vesicles NA NA 660000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 77: Intestine - Digestion" "Cluster 27: Non-specific - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 1: Enterocytes - Absorption and Digestion" Vesicles Nucleoplasm "HPA056417: , HPA075277: " "unprognostic (1.49e-2)" "unprognostic (4.63e-2)" "unprognostic (1.27e-1)" "unprognostic (6.66e-2)" "unprognostic (2.36e-1)" "unprognostic (1.36e-1)" "unprognostic (3.25e-2)" "potential prognostic unfavorable (1.66e-5)" "unprognostic (8.75e-3)" "unprognostic (6.80e-2)" "potential prognostic favorable (7.31e-4)" "unprognostic (1.37e-1)" "unprognostic (9.94e-2)" "unprognostic (7.52e-2)" "unprognostic (3.02e-2)" "unprognostic (9.14e-2)" "unprognostic (2.26e-1)" "unprognostic (3.11e-2)" "unprognostic (2.47e-3)" "unprognostic (1.56e-2)" "unprognostic (3.96e-2)" "validated prognostic unfavorable (6.61e-4)" "validated prognostic unfavorable (9.19e-4)" "unprognostic (3.55e-1)" "unprognostic (2.06e-1)" "unprognostic (1.96e-2)" "unprognostic (1.81e-1)" "unprognostic (1.70e-1)" "unprognostic (2.52e-1)" "unprognostic (9.41e-3)" "unprognostic (1.14e-2)" HEBP2 "C6orf34, SOUL" ENSG00000051620 "Heme binding protein 2" Q9Y5Z4 6 138403531-138422197 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 2706.6;Esophageal suprabasal cells: 724.6;Extravillous trophoblasts: 533.7;Hepatocytes: 651.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016928 Approved NA NA 1400000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 5 "HPA016928: " "unprognostic (8.40e-2)" "unprognostic (1.59e-2)" "unprognostic (2.94e-1)" "unprognostic (2.96e-2)" "unprognostic (6.00e-2)" "unprognostic (3.28e-1)" "unprognostic (1.02e-2)" "unprognostic (3.27e-3)" "unprognostic (4.08e-3)" "unprognostic (2.13e-1)" "unprognostic (1.21e-1)" "unprognostic (5.22e-2)" "unprognostic (2.37e-2)" "unprognostic (1.05e-1)" "unprognostic (1.36e-2)" "unprognostic (6.23e-3)" "unprognostic (5.48e-2)" "unprognostic (2.83e-1)" "unprognostic (1.08e-1)" "unprognostic (4.23e-2)" "unprognostic (5.87e-2)" "unprognostic (1.65e-2)" "unprognostic (1.09e-1)" "unprognostic (2.38e-1)" "unprognostic (3.21e-1)" "unprognostic (3.39e-3)" "unprognostic (1.66e-1)" "unprognostic (1.28e-2)" "unprognostic (1.87e-1)" "unprognostic (1.73e-1)" "unprognostic (5.26e-2)" HECA "dJ225E12.1, HDC, HDCL, hHDC" ENSG00000112406 "Hdc homolog, cell cycle regulator" Q9UBI9 6 139135080-139180802 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Kupffer cells: 266.5;monocytes: 280.2;Neutrophils: 984.5;T-cells: 235.2" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 149.8;leukocyte: 158.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012581, HPA042313" Uncertain Approved Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 58: Skin - Keratinization" "Cluster 19: Astrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 29: Neutrophils - Innate immune cellular maintenance" Cytosol "HPA012581: , HPA042313: " "unprognostic (3.18e-2)" "unprognostic (1.06e-2)" "unprognostic (3.27e-2)" "unprognostic (1.76e-1)" "unprognostic (1.85e-1)" "unprognostic (9.17e-2)" "unprognostic (8.97e-2)" "potential prognostic favorable (3.64e-4)" "unprognostic (8.33e-3)" "unprognostic (1.77e-2)" "potential prognostic favorable (2.34e-5)" "unprognostic (1.08e-3)" "unprognostic (1.81e-3)" "unprognostic (2.02e-2)" "unprognostic (8.62e-2)" "unprognostic (1.91e-1)" "unprognostic (2.09e-1)" "unprognostic (2.42e-1)" "unprognostic (2.58e-2)" "unprognostic (2.36e-3)" "unprognostic (6.46e-2)" "unprognostic (3.15e-2)" "unprognostic (9.87e-2)" "unprognostic (5.03e-1)" "unprognostic (1.63e-2)" "unprognostic (1.00e-2)" "unprognostic (1.85e-1)" "unprognostic (1.36e-1)" "unprognostic (2.22e-1)" "unprognostic (1.64e-2)" "unprognostic (1.50e-1)" HECTD1 KIAA1131 ENSG00000092148 "HECT domain E3 ubiquitin protein ligase 1" Q9ULT8 14 31100117-31207804 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1215.4;Myonuclei: 685.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Stomach - Gastric mucous cells, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002929, HPA054461" Approved Enhanced Nucleoplasm,Nucleoli NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 51: Secretory epithelial cells - Mixed function" 101 "Nucleoplasm, Nucleoli" "HPA002929: , HPA054461: " "unprognostic (1.47e-1)" "unprognostic (1.06e-1)" "unprognostic (3.94e-1)" "unprognostic (2.25e-1)" "potential prognostic favorable (2.39e-4)" "unprognostic (3.21e-3)" "unprognostic (7.92e-2)" "potential prognostic favorable (6.02e-4)" "unprognostic (3.53e-1)" "unprognostic (5.53e-3)" "potential prognostic favorable (1.24e-6)" "unprognostic (1.36e-3)" "unprognostic (1.30e-1)" "unprognostic (1.63e-1)" "unprognostic (1.70e-1)" "unprognostic (1.73e-1)" "unprognostic (1.37e-1)" "unprognostic (2.06e-1)" "unprognostic (1.44e-1)" "unprognostic (8.34e-3)" "unprognostic (1.35e-1)" "potential prognostic unfavorable (7.02e-4)" "unprognostic (1.08e-1)" "unprognostic (2.87e-1)" "unprognostic (2.03e-1)" "unprognostic (7.63e-2)" "unprognostic (9.67e-2)" "unprognostic (4.10e-2)" "unprognostic (1.91e-1)" "unprognostic (1.48e-1)" "unprognostic (1.19e-1)" HECTD2 FLJ37306 ENSG00000165338 "HECT domain E3 ubiquitin protein ligase 2" Q5U5R9 10 91409280-91514829 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglia: 166.8;Myonuclei: 293.6;Papillary tip epithelial cells: 175.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "NK-cell: 2.9" "Lineage enriched" "Detected in single" 5 "NK-cells: 2.9" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 75.4" HPA037767 Approved Approved Nucleoplasm NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 65: Brain - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 1 Nucleoplasm "HPA037767: " "unprognostic (3.64e-2)" "unprognostic (1.25e-1)" "unprognostic (5.95e-2)" "unprognostic (6.69e-2)" "unprognostic (5.15e-2)" "unprognostic (1.83e-1)" "unprognostic (6.66e-2)" "unprognostic (7.29e-2)" "unprognostic (4.41e-2)" "unprognostic (1.19e-1)" "unprognostic (4.24e-1)" "unprognostic (1.32e-2)" "unprognostic (2.60e-1)" "potential prognostic unfavorable (8.96e-4)" "unprognostic (2.80e-2)" "unprognostic (7.55e-2)" "unprognostic (5.43e-2)" "unprognostic (2.14e-2)" "unprognostic (1.87e-1)" "unprognostic (2.90e-1)" "unprognostic (3.47e-1)" "unprognostic (2.36e-3)" "unprognostic (3.70e-2)" "unprognostic (8.75e-2)" "unprognostic (2.61e-2)" "unprognostic (7.47e-2)" "unprognostic (1.50e-1)" "unprognostic (1.87e-2)" "unprognostic (5.60e-2)" "unprognostic (2.97e-2)" "unprognostic (1.39e-1)" HECTD3 FLJ21156 ENSG00000126107 "HECT domain E3 ubiquitin protein ligase 3" Q5T447 1 45002540-45011324 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 35.0;Enterocytes: 49.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027467 Approved NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 77: Intestine - Digestion" "Cluster 6: Non-specific - Immune response" "Cluster 37: Non-specific - mRNA processing" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 40 "HPA027467: " "unprognostic (1.94e-1)" "unprognostic (1.04e-1)" "unprognostic (3.35e-1)" "unprognostic (4.56e-2)" "unprognostic (4.22e-2)" "unprognostic (2.86e-1)" "unprognostic (6.37e-2)" "unprognostic (9.20e-2)" "unprognostic (6.35e-2)" "unprognostic (2.29e-2)" "potential prognostic favorable (4.79e-5)" "unprognostic (5.69e-2)" "unprognostic (1.40e-1)" "potential prognostic unfavorable (5.70e-6)" "unprognostic (1.84e-2)" "unprognostic (5.54e-2)" "unprognostic (2.84e-3)" "unprognostic (2.69e-1)" "unprognostic (3.21e-1)" "unprognostic (8.81e-2)" "unprognostic (3.85e-2)" "unprognostic (3.24e-1)" "unprognostic (1.04e-1)" "unprognostic (6.01e-2)" "unprognostic (1.23e-2)" "unprognostic (1.15e-2)" "unprognostic (2.46e-2)" "unprognostic (4.87e-2)" "unprognostic (1.07e-1)" "potential prognostic favorable (1.56e-4)" "unprognostic (3.97e-2)" HECTD4 "C12orf51, FLJ34154, KIAA0614" ENSG00000173064 "HECT domain E3 ubiquitin protein ligase 4" 12 112160188-112382439 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Choroid plexus epithelial cells: 531.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041062, HPA045473" Uncertain Approved "Nucleoplasm,Nuclear speckles,Vesicles" NA NA "Cluster 32: Basophils - Transcription" "Cluster 27: Cerebellum - Synaptic function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 38: Non-specific - Transcription" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 1 "Nuclear speckles, Vesicles" Nucleoplasm "HPA041062: , HPA045473: " "unprognostic (1.22e-1)" "unprognostic (3.12e-2)" "unprognostic (1.76e-1)" "unprognostic (2.10e-1)" "unprognostic (1.50e-1)" "unprognostic (1.19e-1)" "potential prognostic favorable (4.67e-4)" "unprognostic (8.16e-3)" "potential prognostic unfavorable (7.00e-4)" "validated prognostic favorable (6.41e-5)" "validated prognostic favorable (5.04e-4)" "unprognostic (3.68e-1)" "unprognostic (1.68e-1)" "unprognostic (6.95e-2)" "unprognostic (1.92e-1)" "unprognostic (4.33e-2)" "unprognostic (1.56e-2)" "unprognostic (2.53e-1)" "unprognostic (2.28e-1)" "potential prognostic unfavorable (5.66e-4)" "unprognostic (1.36e-1)" "unprognostic (3.31e-2)" "unprognostic (1.23e-3)" "unprognostic (1.36e-1)" "unprognostic (7.65e-2)" "unprognostic (3.16e-1)" "unprognostic (1.01e-3)" "unprognostic (3.36e-2)" HECW1 "KIAA0322, NEDL1" ENSG00000002746 "HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1" Q76N89 7 43112629-43566001 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 7.6;kidney: 7.3" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 339.5;Brain inhibitory neurons: 256.7;Early spermatids: 287.6;Late spermatids: 173.3;Oligodendrocyte progenitor cells: 426.2;Other brain neurons: 153.2;Proximal tubule cells: 279.1;Retinal amacrine cells: 108.0;Retinal bipolar cells: 273.9;Retinal horizontal cells: 835.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007203, HPA007593, HPA007609" Uncertain Approved "Nucleoli fibrillar center,Cytosol" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 36: Brain & Liver - Signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 7: Liver cancer - Metabolism" "Cluster 109: Neurons - Neuronal signaling" 6 "Nucleoli fibrillar center" Cytosol "HPA007203: , HPA007593: , HPA007609: " "unprognostic (9.55e-2)" "potential prognostic unfavorable (3.95e-4)" "unprognostic (1.45e-3)" "unprognostic (3.51e-2)" "unprognostic (2.85e-1)" "potential prognostic favorable (7.33e-4)" "unprognostic (9.78e-2)" "unprognostic (1.68e-3)" "unprognostic (2.27e-2)" "unprognostic (1.38e-1)" "unprognostic (5.28e-3)" "unprognostic (1.77e-1)" "unprognostic (1.55e-3)" "unprognostic (4.76e-2)" "unprognostic (7.14e-3)" "unprognostic (2.97e-1)" "unprognostic (5.50e-2)" "unprognostic (1.27e-2)" "unprognostic (5.79e-2)" "unprognostic (2.54e-1)" "unprognostic (3.31e-1)" "unprognostic (2.81e-1)" "unprognostic (1.87e-2)" HECW2 "KIAA1301, NEDL2" ENSG00000138411 "HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2" Q9P2P5 2 196189099-196593684 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 387.3;Brain inhibitory neurons: 304.2;Cardiomyocytes: 262.8;Lactotrophs: 243.1;Lymphatic endothelial cells: 262.6;Müller glia: 219.9;Oligodendrocyte progenitor cells: 203.8;Oligodendrocytes: 585.5;Other brain neurons: 190.1;Pancreatic islet cells: 285.7;Pituitary stem cells: 210.6;Retinal ganglion cells: 301.3;Sertoli cells: 382.9;Vascular endothelial cells: 209.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.8;non-classical monocyte: 3.7" "Group enriched" "Detected in many" 8 "granulocytes: 4.8;monocytes: 3.7" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 8.9" "Heart muscle - Cardiomyocytes, Liver - Sinusoid Endothelial cells, Lung - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034609 Enhanced NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 35: Non-specific - Mixed function" "Cluster 34: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 14 "HPA034609: " "unprognostic (7.54e-2)" "unprognostic (9.06e-3)" "unprognostic (3.68e-1)" "unprognostic (1.89e-2)" "unprognostic (1.34e-1)" "unprognostic (2.50e-1)" "potential prognostic favorable (6.87e-5)" "unprognostic (2.97e-1)" "unprognostic (1.89e-1)" "potential prognostic favorable (1.99e-6)" "unprognostic (1.39e-3)" "potential prognostic favorable (1.55e-4)" "unprognostic (2.60e-1)" "unprognostic (2.07e-1)" "unprognostic (1.50e-1)" "unprognostic (5.58e-2)" "unprognostic (8.77e-2)" "unprognostic (9.48e-3)" "unprognostic (7.93e-2)" "unprognostic (2.35e-1)" "unprognostic (3.44e-2)" "unprognostic (8.59e-2)" "unprognostic (1.61e-2)" HEG1 "HEG, KIAA1237" ENSG00000173706 "Heart development protein with EGF like domains 1" Q9ULI3 3 124965710-125055997 "Plasma proteins, Predicted membrane proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 577.6;Epicardial cells: 395.7;Extravillous trophoblasts: 210.9;Mesothelial cells: 823.4;Rod photoreceptor cells: 203.3;Sertoli cells: 172.5;Vascular endothelial cells: 321.6" "Cell type enriched" "Detected in many" 7 "endothelial cell: 788.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 5 "monocytes: 1.3;NK-cells: 2.1;T-cells: 1.1" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Breast - Endothelial cells, Liver - Vascular endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010952, HPA011559" Approved Approved "Vesicles,Plasma membrane" "Intracellular and membrane" "Developmental protein" NA NA 55000000 "Cluster 33: Non-specific - ATP binding" "Cluster 35: Non-specific - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 4 Vesicles "Plasma membrane" "HPA010952: , HPA011559: " "unprognostic (1.13e-1)" "unprognostic (4.52e-2)" "unprognostic (1.09e-1)" "unprognostic (4.74e-2)" "unprognostic (3.80e-2)" "unprognostic (4.47e-3)" "unprognostic (2.35e-1)" "unprognostic (1.35e-2)" "unprognostic (8.70e-2)" "unprognostic (4.34e-2)" "potential prognostic favorable (2.02e-6)" "unprognostic (4.91e-3)" "potential prognostic unfavorable (1.19e-5)" "unprognostic (3.88e-2)" "unprognostic (2.55e-3)" "unprognostic (2.79e-1)" "unprognostic (1.58e-1)" "unprognostic (1.55e-2)" "unprognostic (1.13e-1)" "unprognostic (1.45e-1)" "potential prognostic unfavorable (1.10e-4)" "unprognostic (1.17e-1)" "unprognostic (3.02e-1)" "unprognostic (6.67e-2)" "unprognostic (1.31e-1)" "unprognostic (9.00e-3)" "unprognostic (1.72e-1)" "unprognostic (5.10e-2)" "unprognostic (9.48e-2)" "unprognostic (4.26e-2)" "unprognostic (2.27e-1)" HELB ENSG00000127311 "DNA helicase B" Q8NG08 12 66302493-66343643 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "Neutrophils: 291.4;NK-cells: 122.5;T-cells: 144.6" "Cell type enhanced" "Detected in all" "leukocyte: 162.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039657 Supported "Nucleoplasm,Nuclear bodies,Mitochondria,Cytosol" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 30: White matter - Myelination" "Cluster 55: Lymphoma - Immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 2 Nucleoplasm "Nuclear bodies, Mitochondria, Cytosol" "HPA039657: " "unprognostic (8.60e-3)" "unprognostic (1.38e-2)" "unprognostic (1.58e-1)" "unprognostic (4.96e-2)" "unprognostic (8.23e-2)" HELLS "LSH, Nbla10143, PASG, SMARCA6" ENSG00000119969 "Helicase, lymphoid specific" Q9NRZ9 10 94545329-94613905 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Transcription, Transcription regulation" "Developmental protein, Helicase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 10.5" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 155.1;Early primary spermatocytes: 224.4;Erythrocyte progenitors: 137.9;Megakaryocyte progenitors: 117.4;Monocyte progenitors: 107.4;Respiratory deuterosomal cells: 149.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 64.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Mitotic cells (Lung), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004491, HPA063242" Enhanced Approved "Nucleoplasm,Golgi apparatus,Vesicles" No Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 52: Non-specific - Mitochondria" "Cluster 27: Non-specific - Cell proliferation" 32 Nucleoplasm "Golgi apparatus, Vesicles" "CAB004491: , HPA063242: " "unprognostic (1.77e-1)" "unprognostic (1.57e-1)" "unprognostic (1.95e-1)" "unprognostic (2.86e-3)" "unprognostic (4.31e-1)" "unprognostic (1.34e-1)" "unprognostic (1.65e-1)" "unprognostic (3.93e-2)" "unprognostic (1.10e-1)" "unprognostic (7.32e-3)" "unprognostic (1.04e-1)" "unprognostic (3.11e-2)" "potential prognostic unfavorable (3.39e-4)" "validated prognostic unfavorable (1.33e-5)" "validated prognostic unfavorable (1.68e-4)" "potential prognostic unfavorable (3.75e-4)" "unprognostic (1.45e-3)" "unprognostic (4.08e-3)" "unprognostic (1.23e-1)" "unprognostic (1.98e-1)" "unprognostic (1.48e-1)" "unprognostic (1.81e-3)" "unprognostic (1.66e-3)" "potential prognostic unfavorable (6.42e-5)" "unprognostic (7.41e-2)" "unprognostic (1.12e-2)" "unprognostic (2.05e-3)" "unprognostic (1.51e-2)" "unprognostic (1.51e-1)" "unprognostic (1.95e-2)" "unprognostic (1.62e-2)" HELQ Hel308 ENSG00000163312 "Helicase, POLQ like" Q8TDG4 4 83407343-83455855 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Helicase, Hydrolase, Isomerase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 144.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036852, HPA036853" Approved Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 7 "Nuclear speckles" Nucleoplasm "HPA036852: , HPA036853: " "unprognostic (2.36e-1)" "unprognostic (1.18e-1)" "unprognostic (3.73e-1)" "unprognostic (4.29e-1)" "unprognostic (5.95e-3)" "unprognostic (1.11e-1)" "unprognostic (4.36e-1)" "unprognostic (4.47e-2)" "unprognostic (1.04e-1)" "unprognostic (2.02e-1)" "potential prognostic favorable (8.85e-6)" "unprognostic (1.07e-3)" "unprognostic (4.35e-2)" "unprognostic (2.96e-1)" "unprognostic (5.94e-3)" "unprognostic (2.94e-2)" "unprognostic (3.23e-1)" "unprognostic (3.34e-1)" "unprognostic (3.93e-2)" "unprognostic (1.07e-1)" "unprognostic (4.14e-2)" "unprognostic (5.08e-2)" "unprognostic (7.56e-2)" "unprognostic (2.11e-1)" "unprognostic (8.86e-2)" "unprognostic (5.81e-2)" "unprognostic (1.07e-1)" "unprognostic (6.47e-2)" "unprognostic (3.45e-1)" "unprognostic (6.04e-3)" "unprognostic (6.49e-2)" HELT "bHLHb44, HCM1228, HESL, MEGANE, Mgn" ENSG00000187821 "Helt bHLH transcription factor" A6NFD8 4 185018490-185020953 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "kidney: 1.6" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 2.5;Distal convoluted tubule cells: 1.2" "Cell type enriched" "Detected in single" 5 "choroid plexus epithelial cell: 1.5" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Ascending Loop of Henle cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA036188, HPA036189" Uncertain NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 38: Sub-cortical - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" "HPA036188: , HPA036189: " HELZ "DHRC, HUMORF5, KIAA0054" ENSG00000198265 "Helicase with zinc finger" P42694 17 67070444-67245989 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Sertoli cells: 613.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028276 Approved Approved "Nucleoli,Nucleoli rim,Plasma membrane,Actin filaments" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 45 "Nucleoli, Nucleoli rim" "Plasma membrane, Actin filaments" "HPA028276: " "unprognostic (7.31e-3)" "unprognostic (1.77e-1)" "unprognostic (1.99e-1)" "unprognostic (9.37e-3)" "unprognostic (3.80e-2)" "unprognostic (1.83e-2)" "unprognostic (1.82e-1)" "unprognostic (1.64e-1)" "unprognostic (1.24e-1)" "unprognostic (1.01e-3)" "potential prognostic favorable (1.10e-4)" "unprognostic (7.15e-3)" "unprognostic (1.28e-1)" "unprognostic (6.31e-2)" "unprognostic (1.45e-1)" "unprognostic (3.01e-1)" "unprognostic (4.47e-3)" "unprognostic (6.48e-2)" "unprognostic (5.93e-2)" "unprognostic (1.04e-2)" "unprognostic (3.05e-2)" "unprognostic (1.72e-1)" "unprognostic (1.73e-2)" "unprognostic (1.09e-1)" "unprognostic (9.14e-3)" "unprognostic (7.56e-3)" "unprognostic (1.09e-1)" "unprognostic (7.05e-2)" "unprognostic (1.27e-1)" "unprognostic (2.92e-2)" "unprognostic (3.18e-1)" HELZ2 "KIAA1769, PDIP1, PRIC285" ENSG00000130589 "Helicase with zinc finger 2" Q9BYK8 20 63558086-63574239 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding, Exonuclease, Helicase, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 76.7;Esophageal suprabasal cells: 40.7;Neutrophils: 58.2" "Cell type enhanced" "Detected in some" "endothelial cell: 30.4;fibroblast: 15.8;leukocyte: 14.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Endothelial cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA051267 Uncertain NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 1 "HPA051267: " "unprognostic (4.11e-2)" "unprognostic (3.23e-1)" "unprognostic (1.53e-1)" "unprognostic (3.11e-1)" "unprognostic (7.87e-2)" "unprognostic (8.48e-2)" "unprognostic (2.05e-1)" "unprognostic (1.30e-1)" "unprognostic (1.80e-1)" "unprognostic (1.47e-1)" "unprognostic (2.48e-1)" "unprognostic (7.58e-2)" "unprognostic (2.82e-1)" "unprognostic (1.68e-1)" "unprognostic (3.12e-2)" "unprognostic (3.15e-3)" "unprognostic (1.65e-1)" "unprognostic (8.06e-2)" "unprognostic (1.95e-1)" "unprognostic (8.61e-2)" "unprognostic (8.25e-3)" "unprognostic (9.58e-3)" "unprognostic (6.79e-3)" "unprognostic (1.32e-3)" "unprognostic (3.54e-2)" "unprognostic (3.94e-2)" "unprognostic (1.07e-2)" "unprognostic (8.39e-2)" "unprognostic (1.75e-2)" HEMGN "CT155, EDAG, NDR" ENSG00000136929 Hemogen Q9BXL5 9 97926791-97944856 "Predicted intracellular proteins" Differentiation "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "bone marrow: 232.9" "Cell type enhanced" "Detected in some" "Early spermatids: 1790.2;Erythrocyte progenitors: 544.5;Erythrocytes: 326.5;Hematopoietic stem cells: 174.2;Late spermatids: 2277.6;Megakaryocyte progenitors: 166.5;Megakaryocytes: 463.6;Platelets: 412.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 5.1" "Group enriched" "Detected in many" 28 "granulocytes: 2.2;NK-cells: 2.0;T-cells: 5.1" "Cancer enriched" "Detected in some" 6 "Leukemia: 14.2" "Liver - Erythroid cells, Lung - Neutrophils_1, Spleen - Erythrocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA019572, HPA019604, HPA019606" Enhanced Enhanced Nucleoplasm NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 9: Non-specific - Receptor signaling" "Cluster 47: Leukemia - Hemostasis" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 13 Nucleoplasm "HPA019572: , HPA019604: , HPA019606: " HEMK1 MTQ1 ENSG00000114735 "HemK methyltransferase family member 1" Q9Y5R4 3 50569152-50596168 "Enzymes, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 177.0;Late primary spermatocytes: 66.7;Late spermatids: 221.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034701, HPA034702" Uncertain NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 70: Non-specific - Protein processing" "Cluster 3: Choroid plexus - Cilium" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 18 "HPA034701: , HPA034702: " "unprognostic (5.48e-2)" "unprognostic (3.81e-2)" "unprognostic (1.30e-1)" "unprognostic (1.83e-1)" "unprognostic (2.07e-1)" "unprognostic (2.82e-2)" "unprognostic (5.50e-3)" "unprognostic (1.40e-1)" "unprognostic (8.67e-2)" "unprognostic (2.63e-2)" "unprognostic (2.49e-2)" "unprognostic (4.85e-2)" "potential prognostic favorable (1.25e-9)" "unprognostic (1.24e-1)" "unprognostic (2.52e-2)" "unprognostic (2.85e-2)" "unprognostic (3.18e-2)" "unprognostic (1.64e-1)" "unprognostic (1.78e-1)" "unprognostic (4.85e-2)" "unprognostic (1.90e-1)" "unprognostic (1.25e-1)" "unprognostic (1.94e-1)" "unprognostic (1.58e-1)" "unprognostic (5.50e-3)" "unprognostic (1.07e-1)" "unprognostic (1.38e-1)" "unprognostic (3.87e-2)" "unprognostic (5.14e-2)" "unprognostic (6.91e-2)" "unprognostic (9.70e-2)" HENMT1 "C1orf59, FLJ30525, HEN1" ENSG00000162639 "HEN methyltransferase 1" Q5T8I9 1 108648290-108661526 "Enzymes, Predicted intracellular proteins" "RNA-mediated gene silencing" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 67.3" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 71.6;Early primary spermatocytes: 150.0;Late primary spermatocytes: 181.4;Oocytes: 405.2;Undifferentiated spermatogonia: 119.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in many" "Region enriched" "Detected in single" 16 "cerebellum: 12.2" "HPA028464, HPA028497" Uncertain Approved "Plasma membrane,Focal adhesion sites" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 35: RS4;11 - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 2 "Plasma membrane, Focal adhesion sites" "HPA028464: , HPA028497: " "unprognostic (1.82e-1)" "unprognostic (1.41e-1)" "potential prognostic favorable (1.48e-4)" "unprognostic (3.24e-2)" "unprognostic (1.32e-3)" "unprognostic (2.59e-1)" "unprognostic (2.22e-1)" "unprognostic (2.48e-3)" "unprognostic (9.41e-2)" "unprognostic (1.24e-1)" "unprognostic (9.27e-2)" "unprognostic (5.15e-2)" "unprognostic (5.77e-2)" "unprognostic (1.27e-1)" "unprognostic (2.03e-1)" "unprognostic (2.76e-1)" "unprognostic (1.77e-1)" "unprognostic (1.66e-1)" "unprognostic (2.82e-2)" "unprognostic (1.25e-1)" "unprognostic (8.00e-2)" "unprognostic (7.07e-2)" "potential prognostic favorable (9.52e-4)" "unprognostic (1.04e-1)" "unprognostic (2.92e-1)" "unprognostic (2.01e-1)" "unprognostic (1.33e-1)" "unprognostic (1.90e-1)" "unprognostic (1.32e-2)" HEPACAM "FLJ25530, GLIALCAM" ENSG00000165478 "Hepatic and glial cell adhesion molecule" Q14CZ8 11 124919205-124936412 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cell adhesion, Cell cycle, Growth arrest, Growth regulation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 14.8;brain: 55.0;liver: 15.0" "Cell type enhanced" "Detected in some" "Adipocytes: 63.7;Astrocytes: 265.1;Bergmann glia: 267.7;Ependymal cells: 76.2;Oligodendrocyte progenitor cells: 130.8;Oligodendrocytes: 236.6" "Group enriched" "Detected in many" 29 "astrocyte: 266.7;Bergmann glia: 279.6;committed oligodendrocyte precursor: 106.5;ependymal cell: 82.1;oligodendrocyte: 286.9;oligodendrocyte precursor cell: 135.0" "Cancer enriched" "Detected in many" 17 "Glioblastoma Multiforme (TCGA): 81.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "liver cancer: 1.4" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Minor Salivary Gland - Adipocytes (Minor salivary gland), Skin - Adipocytes (Skin)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017613, CAB025486" Enhanced Approved Vesicles NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 39: Astrocytes - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 28: Astrocytes - Homeostasis & neuron support" Vesicles "CAB025486: , HPA017613: " "unprognostic (1.69e-1)" "unprognostic (1.21e-3)" "unprognostic (1.60e-1)" "unprognostic (6.93e-3)" "unprognostic (1.15e-1)" "unprognostic (9.03e-3)" "unprognostic (1.55e-1)" "unprognostic (1.36e-1)" "unprognostic (3.93e-1)" "unprognostic (2.29e-1)" HEPACAM2 FLJ38683 ENSG00000188175 "HEPACAM family member 2" A8MVW5 7 93188534-93226469 "Predicted membrane proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "intestine: 90.3" "Cell type enhanced" "Detected in some" "Epididymal clear cells: 338.9;Goblet cells: 619.3;Neuroendocrine cells: 232.5;Paneth cells: 69.6;Renal collecting duct intercalated cells: 122.6;Respiratory ionocytes: 340.4;Salivary ionocytes: 212.4;Tuft cells: 334.3" "Cell type enhanced" "Detected in some" "ependymal cell: 3.7" "Cancer enriched" "Detected in many" 10 "Kidney Chromophobe (TCGA): 172.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Gastric cancer: 10.1;lung cancer: 25.6" "Breast - Breast glandular cells, Colon - Colon enterocytes, Kidney - Intercalated cells, Minor Salivary Gland - Minor salivary gland ductal cells, Pancreas - Alpha cells, Pancreas - Beta cells, Pituitary gland - Lactotropes, Spleen - Erythrocytes, Stomach - Gastric enteroendocrine cells, Testis - Early spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA012381 Supported "Nucleoplasm,Vesicles,Mitotic spindle" Yes NA 110000 "Cluster 77: Intestine - Digestion" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 70: Intestinal goblet cells - Mucin production" "Vesicles, Mitotic spindle" Nucleoplasm "HPA012381: " "unprognostic (1.57e-1)" "unprognostic (2.56e-3)" "unprognostic (8.46e-2)" "potential prognostic favorable (4.74e-4)" "unprognostic (1.03e-1)" "unprognostic (2.72e-1)" "unprognostic (1.37e-3)" "unprognostic (1.83e-1)" "unprognostic (4.59e-2)" "unprognostic (1.20e-2)" "unprognostic (2.35e-1)" "unprognostic (2.91e-1)" "unprognostic (7.12e-3)" "unprognostic (1.74e-1)" "unprognostic (4.16e-2)" "unprognostic (2.02e-2)" "unprognostic (8.71e-3)" "unprognostic (2.26e-1)" HEPH "CPL, KIAA0698" ENSG00000089472 Hephaestin Q9BQS7 X 66162671-66268867 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Iron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 55.1;smooth muscle: 51.4" "Cell type enhanced" "Detected in many" "Astrocytes: 105.6;Colonocytes: 322.5;Enteric stem cells: 98.7;Enteric transient amplifying cells: 146.1;Enterocytes: 297.3;Goblet cells: 233.5;Neuroendocrine cells: 76.9;Tuft cells: 138.3" "Group enriched" "Detected in many" 4 "astrocyte: 120.4;Bergmann glia: 63.6;ependymal cell: 46.0;fibroblast: 66.2;oligodendrocyte: 35.6;pericyte: 50.0;vascular associated smooth muscle cell: 44.7" "Cancer enhanced" "Detected in all" "Colon Adenocarcinoma (TCGA): 85.8;Rectum Adenocarcinoma (TCGA): 80.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 19.2;testis cancer: 40.2" "Adipose visceral - Adipose progenitor cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Spleen - Fibroblasts_2, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA005824 Approved NA NA 1000000 "Cluster 77: Intestine - Digestion" "Cluster 19: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" "HPA005824: " "unprognostic (7.51e-3)" "unprognostic (1.52e-1)" "unprognostic (4.62e-2)" "unprognostic (1.50e-2)" "unprognostic (1.08e-2)" "unprognostic (1.44e-2)" "unprognostic (9.31e-3)" "unprognostic (5.38e-3)" "unprognostic (2.04e-1)" "unprognostic (6.27e-3)" "validated prognostic favorable (7.38e-6)" "validated prognostic favorable (2.01e-4)" "potential prognostic unfavorable (1.19e-4)" "unprognostic (1.04e-1)" "unprognostic (7.00e-3)" "unprognostic (1.80e-2)" "unprognostic (1.02e-1)" "unprognostic (1.39e-1)" "unprognostic (2.32e-2)" "unprognostic (1.60e-1)" "unprognostic (1.60e-3)" "unprognostic (2.07e-3)" "unprognostic (1.88e-3)" "unprognostic (2.61e-1)" "unprognostic (8.12e-3)" "unprognostic (1.53e-1)" "unprognostic (9.28e-3)" "unprognostic (6.24e-2)" "unprognostic (6.29e-2)" "unprognostic (4.37e-2)" "unprognostic (2.25e-1)" HEPHL1 "DKFZp686F22190, Zp" ENSG00000181333 "Hephaestin like 1" Q6MZM0 11 94021354-94114208 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Transporters" "Copper transport, Ion transport, Transport" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "cervix: 9.3;esophagus: 4.2;lymphoid tissue: 8.9;skin 1: 3.2;vagina: 4.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 37.6;Epicardial cells: 45.5;Esophageal apical cells: 161.6;Esophageal suprabasal cells: 16.8;Suprabasal keratinocytes: 79.0;Tuft cells: 23.1" "Low cell type specificity" "Detected in some" "Cancer enriched" "Detected in some" 5 "Head and Neck Squamous Cell Carcinoma (TCGA): 26.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "Bladder cancer: 4.7;colorectal cancer: 4.4;head and neck cancer: 9.4" "Skin - Hair cortex cells, Skin - Inner root sheath cells" "Region enriched" "Detected in single" 12 "olfactory bulb: 1.2" "Not detected" "Not detected" HPA031517 Uncertain NA NA 150000000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 17 "HPA031517: " "unprognostic (3.37e-2)" "unprognostic (1.51e-2)" "unprognostic (1.42e-3)" "unprognostic (3.48e-1)" "unprognostic (4.38e-2)" "unprognostic (3.94e-3)" "unprognostic (4.74e-2)" "unprognostic (2.43e-1)" HEPN1 ENSG00000221932 "Hepatocellular carcinoma, down-regulated 1" Q6WQI6 11 124919250-124920677 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 8 "brain: 162.7" "Cell type enhanced" "Detected in some" "Adipocytes: 48.4;Astrocytes: 171.4;Bergmann glia: 250.7;Ependymal cells: 33.9;Müller glia: 29.4;Oligodendrocyte progenitor cells: 77.4;Oligodendrocytes: 158.6" "Group enriched" "Detected in many" 4 "astrocyte: 145.3;Bergmann glia: 306.2;oligodendrocyte: 186.6;oligodendrocyte precursor cell: 83.6" "Cancer enriched" "Detected in some" 10 "Glioblastoma Multiforme (TCGA): 141.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "liver cancer: 1.1" "HPA043768, HPA063054" Uncertain Approved "Golgi apparatus" Yes NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 28: Astrocytes - Homeostasis & neuron support" "Golgi apparatus" "HPA043768: , HPA063054: " "unprognostic (1.32e-2)" "unprognostic (9.39e-2)" "unprognostic (1.49e-1)" "unprognostic (5.75e-3)" HERC1 "p532, p619" ENSG00000103657 "HECT and RLD domain containing E3 ubiquitin protein ligase family member 1" Q15751 15 63608618-63833948 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Transport, Ubl conjugation pathway" "Guanine-nucleotide releasing factor, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Myonuclei: 906.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049749 Uncertain NA NA "Cluster 32: Basophils - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 53: Neurons - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 55: Myocytes - Oxidative muscle function" 30 "HPA049749: " "unprognostic (4.85e-2)" "unprognostic (1.06e-1)" "unprognostic (7.87e-2)" "unprognostic (1.05e-2)" "unprognostic (2.63e-1)" "unprognostic (1.33e-1)" "unprognostic (1.75e-1)" "potential prognostic favorable (2.05e-4)" "unprognostic (3.88e-3)" "unprognostic (3.62e-3)" "validated prognostic favorable (1.91e-6)" "validated prognostic favorable (1.54e-5)" "unprognostic (1.96e-2)" "unprognostic (1.05e-1)" "unprognostic (1.82e-2)" "unprognostic (3.34e-2)" "unprognostic (5.36e-2)" "unprognostic (1.05e-1)" "unprognostic (7.65e-2)" "unprognostic (1.93e-2)" "unprognostic (1.92e-1)" "unprognostic (8.06e-2)" "unprognostic (8.09e-3)" "unprognostic (3.40e-1)" "unprognostic (5.30e-2)" "unprognostic (1.41e-2)" "unprognostic (1.22e-2)" "unprognostic (2.36e-1)" "unprognostic (2.50e-1)" "unprognostic (9.97e-2)" "unprognostic (5.84e-3)" HERC2 "D15F37S1, jdf2, p528" ENSG00000128731 "HECT and RLD domain containing E3 ubiquitin protein ligase 2" O95714 15 28111040-28322179 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bergmann glia: 136.3;Choroid plexus epithelial cells: 154.5;Distal convoluted tubule cells: 244.9;Loop of henle epithelial cells: 180.3;Podocytes: 188.9;Proximal tubule cells: 217.1;Renal collecting duct intercalated cells: 198.2;Renal collecting duct principal cells: 175.0;Renal connecting tubule cells: 218.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017188, HPA048389, HPA074166" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 63: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 102: Non-specific - Mixed function" 104 Cytosol "Plasma membrane" "CAB017188: , HPA048389: , HPA074166: " "unprognostic (2.11e-3)" "unprognostic (3.55e-2)" "unprognostic (1.17e-1)" "unprognostic (5.63e-2)" "unprognostic (3.72e-2)" "unprognostic (4.46e-2)" "unprognostic (2.85e-2)" "unprognostic (3.47e-3)" "unprognostic (2.10e-2)" "unprognostic (1.89e-3)" "validated prognostic favorable (3.33e-7)" "validated prognostic favorable (1.79e-4)" "unprognostic (7.52e-2)" "unprognostic (2.59e-1)" "unprognostic (2.05e-1)" "unprognostic (2.19e-1)" "unprognostic (3.43e-2)" "unprognostic (9.35e-3)" "unprognostic (9.89e-3)" "unprognostic (3.65e-3)" "unprognostic (1.98e-1)" "unprognostic (5.12e-3)" "unprognostic (1.01e-1)" "unprognostic (3.94e-2)" "unprognostic (1.80e-3)" "unprognostic (4.16e-1)" "unprognostic (1.82e-1)" "unprognostic (1.60e-1)" "unprognostic (3.49e-3)" "unprognostic (2.02e-1)" HERC3 KIAA0032 ENSG00000138641 "HECT and RLD domain containing E3 ubiquitin protein ligase 3" Q15034 4 88592434-88708541 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "retina: 105.6" "Cell type enhanced" "Detected in many" "Astrocytes: 68.2;Bergmann glia: 48.1;Brain excitatory neurons: 94.8;Brain inhibitory neurons: 100.9;Choroid plexus epithelial cells: 115.2;Distal convoluted tubule cells: 75.1;Loop of henle epithelial cells: 51.1;Microglia: 184.3;Oligodendrocyte progenitor cells: 67.7;Oligodendrocytes: 113.0;Other brain neurons: 68.5;Renal collecting duct intercalated cells: 54.9;Renal connecting tubule cells: 90.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "prostate cancer: 37.0" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039170 Approved Supported Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 37: Neurons - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 22: Non-specific - Basic cellular functions" 15 Cytosol "HPA039170: " "unprognostic (1.32e-1)" "unprognostic (1.41e-2)" "unprognostic (1.60e-3)" "potential prognostic favorable (6.65e-5)" "unprognostic (1.67e-2)" "unprognostic (1.33e-1)" "unprognostic (7.81e-2)" "unprognostic (3.09e-2)" "unprognostic (1.81e-2)" "validated prognostic favorable (1.47e-8)" "validated prognostic favorable (1.36e-5)" "unprognostic (1.06e-2)" "unprognostic (6.13e-2)" "unprognostic (1.25e-1)" "unprognostic (1.72e-1)" "unprognostic (5.68e-2)" "unprognostic (4.03e-1)" "unprognostic (4.29e-3)" "unprognostic (1.46e-1)" "unprognostic (8.92e-3)" "unprognostic (4.71e-3)" "unprognostic (4.93e-2)" "unprognostic (8.47e-2)" "unprognostic (1.27e-1)" "unprognostic (9.01e-2)" "unprognostic (1.36e-1)" "unprognostic (2.46e-1)" "unprognostic (4.22e-1)" "unprognostic (2.58e-1)" HERC3 KIAA0032 ENSG00000287542 "HECT and RLD domain containing E3 ubiquitin protein ligase 3" 4 88523810-88708450 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 7.9" "Cell type enriched" "Detected in many" 12 "Cardiomyocytes: 322.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 5.1" HPA039170 Uncertain Approved Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 42: Retina - Visual perception" "Cluster 44: Non-specific - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 10 Cytosol "HPA039170: " "unprognostic (1.32e-1)" "unprognostic (4.70e-2)" "unprognostic (1.76e-2)" "unprognostic (1.87e-1)" "validated prognostic favorable (8.59e-8)" "validated prognostic favorable (1.18e-4)" "unprognostic (2.36e-1)" "unprognostic (3.54e-1)" "unprognostic (2.08e-1)" "unprognostic (2.10e-2)" "unprognostic (1.21e-1)" HERC4 "DKFZP564G092, KIAA1593" ENSG00000148634 "HECT and RLD domain containing E3 ubiquitin protein ligase 4" Q5GLZ8 10 67921899-68075301 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Spermatogenesis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 727.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 147.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045453, HPA070301" Uncertain Approved "Nucleoli fibrillar center,Primary cilium,Primary cilium tip,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 7: Non-specific - Transcription" 5 "Nucleoli fibrillar center, Cytosol" "Primary cilium, Primary cilium tip" "HPA045453: , HPA070301: " "unprognostic (6.61e-3)" "unprognostic (2.82e-2)" "unprognostic (9.52e-2)" "unprognostic (2.63e-1)" "unprognostic (1.35e-1)" "unprognostic (5.06e-1)" "unprognostic (1.20e-1)" "potential prognostic favorable (4.35e-4)" "unprognostic (2.28e-1)" "unprognostic (8.53e-2)" "unprognostic (3.41e-1)" "unprognostic (5.35e-2)" "unprognostic (3.60e-1)" "unprognostic (2.62e-2)" "unprognostic (1.06e-1)" "unprognostic (4.70e-3)" "unprognostic (1.21e-1)" "unprognostic (2.44e-2)" "unprognostic (2.19e-1)" "unprognostic (4.05e-2)" "unprognostic (3.22e-3)" "unprognostic (2.13e-2)" "unprognostic (1.24e-3)" "unprognostic (3.12e-2)" "unprognostic (2.02e-2)" "unprognostic (1.87e-2)" "unprognostic (1.68e-1)" "unprognostic (4.11e-2)" "unprognostic (2.86e-2)" "unprognostic (3.28e-2)" "unprognostic (7.57e-2)" HERC5 CEB1 ENSG00000138646 "HECT and RLD domain containing E3 ubiquitin protein ligase 5" Q9UII4 4 88457119-88506163 "Predicted membrane proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 54.1" "Group enriched" "Detected in many" 4 "Differentiating spermatogonia: 512.7;Early primary spermatocytes: 470.2;Oocytes: 165.8;Undifferentiated spermatogonia: 137.5" "Cell type enhanced" "Detected in many" "endothelial cell: 52.3;oligodendrocyte precursor cell: 36.4" "Cancer enriched" "Detected in all" 5 "Testicular Germ Cell Tumor (TCGA): 67.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in many" HPA043929 Supported NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 57: Testis - Spermatogenesis" "Cluster 46: Brainstem - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 45 "HPA043929: " "unprognostic (7.41e-2)" "unprognostic (6.88e-2)" "unprognostic (2.94e-1)" "unprognostic (9.51e-3)" "unprognostic (1.14e-1)" "unprognostic (6.96e-2)" "unprognostic (4.35e-1)" "unprognostic (1.74e-2)" "unprognostic (1.73e-1)" "unprognostic (2.31e-2)" "potential prognostic favorable (9.97e-5)" "unprognostic (1.37e-1)" "unprognostic (2.08e-1)" "unprognostic (6.90e-3)" "unprognostic (6.06e-2)" "unprognostic (1.16e-1)" "unprognostic (1.58e-2)" "unprognostic (7.63e-2)" "unprognostic (2.60e-1)" "unprognostic (1.37e-1)" "unprognostic (7.07e-2)" "unprognostic (1.05e-1)" "unprognostic (2.22e-2)" "unprognostic (4.37e-2)" "unprognostic (1.77e-1)" "potential prognostic favorable (1.23e-5)" "unprognostic (4.32e-2)" "unprognostic (9.26e-2)" "unprognostic (1.07e-1)" "unprognostic (1.44e-1)" "unprognostic (1.66e-3)" HERC6 FLJ20637 ENSG00000138642 "HECT and RLD domain containing E3 ubiquitin protein ligase family member 6" Q8IVU3 4 88378739-88443097 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 93.8" "Cell type enhanced" "Detected in all" "endothelial cell: 133.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035846 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 53: Neurons - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 104: Brain endothelial cells - Blood brain barrier" 1 Cytosol Nucleoplasm "HPA035846: " "unprognostic (3.28e-2)" "unprognostic (8.29e-2)" "unprognostic (2.26e-1)" "unprognostic (2.84e-2)" "unprognostic (1.88e-2)" "unprognostic (2.05e-1)" "unprognostic (5.21e-2)" "unprognostic (2.11e-1)" "unprognostic (7.06e-2)" "unprognostic (1.78e-1)" "validated prognostic favorable (8.00e-4)" "validated prognostic favorable (6.85e-4)" "potential prognostic favorable (3.13e-4)" "unprognostic (5.73e-3)" "unprognostic (1.20e-3)" "unprognostic (1.51e-1)" "unprognostic (1.82e-1)" "unprognostic (1.50e-1)" "unprognostic (2.88e-1)" "unprognostic (1.90e-1)" "unprognostic (3.15e-1)" "unprognostic (8.63e-3)" "unprognostic (6.32e-2)" "unprognostic (3.14e-1)" "unprognostic (3.74e-2)" "unprognostic (1.60e-3)" "unprognostic (4.52e-1)" "unprognostic (1.95e-1)" "unprognostic (2.51e-1)" "unprognostic (2.65e-2)" "unprognostic (1.07e-1)" HERPUD1 "HERP, KIAA0025, Mif1, SUP" ENSG00000051108 "Homocysteine inducible ER protein with ubiquitin like domain 1" Q15011 16 56932142-56944864 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Unfolded protein response" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epididymal basal cells: 1425.4;Epididymal principal cells: 1965.2;pDCs: 1257.3;Plasma cells: 2701.2;Syncytiotrophoblasts: 975.7" "Cell type enhanced" "Detected in all" "endothelial cell: 645.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Myeloma: 300.3" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037041, CAB037104, HPA040754, HPA041219" Approved Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 70: Non-specific - Protein processing" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 13: Non-specific - Mixed function" "Cluster 78: Plasma cells - Antibody production & ER-stress response" 15 "Plasma membrane, Cytosol" "CAB037041: , CAB037104: , HPA040754: , HPA041219: " "unprognostic (2.56e-2)" "unprognostic (9.38e-3)" "unprognostic (1.66e-1)" "unprognostic (2.33e-1)" "unprognostic (2.39e-1)" "unprognostic (7.34e-2)" "unprognostic (1.32e-1)" "unprognostic (3.04e-3)" "unprognostic (5.21e-2)" "unprognostic (2.17e-1)" "potential prognostic favorable (1.32e-8)" "unprognostic (6.10e-2)" "unprognostic (2.40e-2)" "unprognostic (9.88e-2)" "unprognostic (1.02e-1)" "potential prognostic favorable (1.29e-4)" "unprognostic (1.30e-3)" "unprognostic (3.49e-2)" "unprognostic (2.79e-1)" "unprognostic (2.52e-1)" "unprognostic (1.04e-3)" "unprognostic (1.90e-1)" "unprognostic (4.79e-2)" "unprognostic (2.90e-1)" "unprognostic (8.19e-2)" "unprognostic (1.35e-1)" "unprognostic (2.14e-1)" "unprognostic (1.34e-1)" "unprognostic (1.75e-1)" "unprognostic (3.44e-2)" "unprognostic (8.38e-3)" HERPUD2 FLJ22313 ENSG00000122557 "HERPUD family member 2" Q9BSE4 7 35632659-35697459 "Predicted intracellular proteins, Predicted membrane proteins" "Unfolded protein response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 373.0;Late spermatids: 984.6;Neutrophils: 228.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015630, HPA076087" Approved Approved "Nucleoli,Nucleoli rim" No No "Cluster 45: Eosinophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 67: Non-specific - Unknown function" "Cluster 9: T-cells - Adaptive immunity: Regulation" 16 "Nucleoli, Nucleoli rim" "HPA015630: , HPA076087: " "unprognostic (1.45e-1)" "unprognostic (3.76e-2)" "unprognostic (1.87e-1)" "potential prognostic unfavorable (7.73e-6)" "unprognostic (1.46e-1)" "unprognostic (5.51e-2)" "unprognostic (1.64e-1)" "unprognostic (7.95e-2)" "unprognostic (9.86e-3)" "potential prognostic unfavorable (2.43e-4)" "validated prognostic favorable (2.48e-5)" "validated prognostic favorable (6.80e-4)" "unprognostic (2.37e-1)" "unprognostic (1.49e-1)" "unprognostic (2.47e-1)" "unprognostic (6.91e-2)" "unprognostic (1.99e-1)" "unprognostic (2.03e-1)" "unprognostic (3.11e-1)" "unprognostic (3.87e-2)" "unprognostic (1.51e-2)" "unprognostic (4.14e-1)" "unprognostic (4.09e-3)" "unprognostic (1.58e-1)" "unprognostic (5.12e-2)" "unprognostic (2.45e-2)" "unprognostic (1.51e-1)" "unprognostic (3.70e-2)" "unprognostic (5.83e-2)" "unprognostic (2.26e-3)" "unprognostic (1.74e-1)" HES1 "bHLHb39, FLJ20408, HES-1, HRY" ENSG00000114315 "Hes family bHLH transcription factor 1" Q14469 3 194136148-194138732 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Colonocytes: 1050.4;Enteric stem cells: 1531.2;Enteric transient amplifying cells: 1065.2;Epididymal basal cells: 1237.6;Epididymal efferent duct absorptive cells: 1040.7;Epididymal principal cells: 969.1;Esophageal apical cells: 1122.3;Granulosa cells: 1612.3;Müller glia: 1103.8;Prostatic club cells: 1127.0;Prostatic hillock cells: 1245.6" "Group enriched" "Detected in many" 12 "astrocyte: 200.3;Bergmann glia: 85.5;endothelial cell: 134.8;ependymal cell: 130.0;fibroblast: 62.2;pericyte: 77.6;vascular associated smooth muscle cell: 50.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 8 "eosinophil: 15.6" "Lineage enriched" "Detected in many" 8 "granulocytes: 15.6" "Low cancer specificity" "Detected in all" "Prostate - Urothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066929 Supported Nucleoplasm NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 58: Skin - Keratinization" "Cluster 44: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 20 Nucleoplasm "HPA066929: " "unprognostic (1.49e-2)" "unprognostic (4.67e-3)" "unprognostic (3.64e-1)" "unprognostic (1.99e-1)" "potential prognostic favorable (5.50e-4)" "unprognostic (1.34e-1)" "unprognostic (4.71e-2)" "unprognostic (5.00e-3)" "unprognostic (1.10e-1)" "unprognostic (1.17e-2)" "unprognostic (1.33e-1)" "potential prognostic favorable (7.74e-4)" "unprognostic (2.14e-1)" "unprognostic (5.65e-2)" "unprognostic (5.83e-2)" "unprognostic (5.03e-2)" "unprognostic (1.09e-2)" "unprognostic (5.07e-2)" "unprognostic (3.87e-2)" "unprognostic (9.01e-2)" "unprognostic (1.21e-1)" "unprognostic (5.50e-3)" "unprognostic (2.44e-3)" "unprognostic (4.77e-2)" "unprognostic (1.06e-1)" "unprognostic (6.99e-2)" "unprognostic (2.89e-1)" "unprognostic (5.07e-2)" "unprognostic (2.50e-1)" "unprognostic (1.27e-1)" "unprognostic (7.87e-2)" HES2 bHLHb40 ENSG00000069812 "Hes family bHLH transcription factor 2" Q9Y543 1 6412418-6424670 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "cervix: 17.6;esophagus: 32.0;skin 1: 16.1;vagina: 17.9" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 48.8;Esophageal basal cells: 89.6;Esophageal suprabasal cells: 117.0;Fallopian tube ciliated cells: 37.1;Goblet cells: 52.0;Late spermatids: 87.8;Ocular epithelial cells: 90.7;Suprabasal keratinocytes: 51.4;Syncytiotrophoblasts: 141.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 41.8;Head and Neck Squamous Cell Carcinoma (TCGA): 34.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "basophil: 2.7;neutrophil: 1.0" "Lineage enriched" "Detected in single" 11 "granulocytes: 2.7" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 36.3;head and neck cancer: 37.3" "Colon - Colon enterocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA039462 Uncertain NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." "HPA039462: " "unprognostic (2.34e-1)" "unprognostic (1.02e-1)" "unprognostic (3.14e-2)" "unprognostic (1.61e-2)" "unprognostic (1.11e-1)" "unprognostic (1.16e-3)" "unprognostic (1.92e-1)" "unprognostic (8.05e-2)" "unprognostic (5.84e-2)" "potential prognostic favorable (1.04e-4)" "unprognostic (3.93e-2)" "unprognostic (3.61e-2)" "unprognostic (2.90e-1)" "unprognostic (8.28e-3)" "unprognostic (4.38e-2)" "unprognostic (3.55e-1)" "unprognostic (2.29e-3)" "unprognostic (5.81e-3)" "unprognostic (3.67e-2)" "unprognostic (4.93e-1)" "unprognostic (2.36e-1)" "unprognostic (1.13e-2)" "unprognostic (1.01e-1)" "unprognostic (1.12e-1)" "unprognostic (8.05e-2)" "unprognostic (1.70e-1)" HES3 bHLHb43 ENSG00000173673 "Hes family bHLH transcription factor 3" Q5TGS1 1 6244179-6245578 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 17 "Testicular Germ Cell Tumor (TCGA): 1.7" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in some" 30 "cerebellum: 34.8" "Low region specificity" "Detected in some" "HPA047927, HPA072697" Uncertain Approved Nucleoplasm NA NA "Cluster 38: Sub-cortical - Mixed function" "Cluster 34: Testis cancer - Unknown function" Nucleoplasm "HPA047927: , HPA072697: " "unprognostic (2.37e-1)" HES4 bHLHb42 ENSG00000188290 "Hes family bHLH transcription factor 4" Q9HCC6 1 998962-1000172 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 30.8" "Cell type enhanced" "Detected in many" "Epididymal efferent duct absorptive cells: 415.6;Fallopian secretory cells: 433.5;Pericytes: 356.3;Respiratory deuterosomal cells: 254.0;Respiratory secretory cells: 290.0;Urothelial cells: 483.2;Vascular smooth muscle cells: 647.4" "Group enriched" "Detected in all" 9 "pericyte: 1049.2;vascular associated smooth muscle cell: 439.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 10 "eosinophil: 12.5" "Lineage enriched" "Detected in many" 10 "granulocytes: 12.5" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells" "Low region specificity" "Detected in all" HPA062465 Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 27: Non-specific - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 103: Non-specific - Basic cellular processes" 6 Nucleoplasm "Vesicles, Cytosol" "HPA062465: " "unprognostic (4.73e-2)" "unprognostic (9.49e-2)" "unprognostic (1.85e-1)" "unprognostic (2.10e-3)" "unprognostic (6.79e-3)" "unprognostic (1.08e-1)" "unprognostic (2.23e-2)" "unprognostic (2.78e-3)" "unprognostic (6.11e-2)" "unprognostic (2.67e-1)" "unprognostic (9.15e-2)" "unprognostic (2.21e-2)" "unprognostic (2.41e-1)" "potential prognostic unfavorable (3.55e-4)" "unprognostic (4.30e-2)" "unprognostic (2.27e-3)" "unprognostic (1.26e-1)" "unprognostic (4.99e-2)" "unprognostic (1.78e-1)" "unprognostic (1.58e-1)" "unprognostic (3.85e-2)" "unprognostic (1.29e-1)" "unprognostic (1.13e-3)" "unprognostic (2.75e-1)" "unprognostic (2.07e-2)" "unprognostic (4.77e-2)" "unprognostic (1.82e-1)" "unprognostic (2.40e-1)" "unprognostic (1.50e-1)" "unprognostic (1.39e-1)" "unprognostic (1.50e-1)" HES5 bHLHb38 ENSG00000197921 "Hes family bHLH transcription factor 5" Q5TA89 1 2528745-2530263 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 15.3;skin 1: 4.8" "Group enriched" "Detected in some" 35 "Astrocytes: 87.3;Bergmann glia: 67.9;Oligodendrocyte progenitor cells: 78.8" "Group enriched" "Detected in many" 5 "astrocyte: 89.0;Bergmann glia: 84.6;oligodendrocyte precursor cell: 54.0" "Cancer enriched" "Detected in single" 11 "Glioblastoma Multiforme (TCGA): 3.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA065458, HPA076164" Enhanced Approved "Nucleoplasm,Nuclear speckles,Cytosol" No NA "Cluster 78: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 70: DU4475 - Unknown function" "Cluster 28: Astrocytes - Homeostasis & neuron support" 1 Nucleoplasm "Nuclear speckles, Cytosol" "HPA065458: , HPA076164: " "unprognostic (2.77e-2)" "unprognostic (1.22e-1)" "validated prognostic favorable (4.89e-4)" "validated prognostic favorable (3.13e-5)" "unprognostic (1.31e-2)" HES6 bHLHb41 ENSG00000144485 "Hes family bHLH transcription factor 6" Q96HZ4 2 238238267-238240662 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 56.2;pituitary gland: 61.7" "Cell type enhanced" "Detected in many" "Fallopian tube ciliated cells: 113.8;Goblet cells: 116.7;Late primary spermatocytes: 86.1;Oocytes: 119.7;Paneth cells: 170.2;Respiratory deuterosomal cells: 197.0;Respiratory ionocytes: 355.6;Somatotrophs: 167.4" "Cell type enhanced" "Detected in many" "Bergmann glia: 61.8" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 164.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "eosinophil: 5.1" "Lineage enriched" "Detected in single" 7 "granulocytes: 5.1" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073997 Approved "Nuclear bodies,Cytosol" NA No "Cluster 45: Eosinophils - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 70: Intestinal goblet cells - Mucin production" 8 "Nuclear bodies" Cytosol "HPA073997: " "unprognostic (8.26e-3)" "unprognostic (1.74e-1)" "unprognostic (1.37e-1)" "unprognostic (2.33e-1)" "unprognostic (1.57e-1)" "unprognostic (1.72e-1)" "unprognostic (1.75e-2)" "unprognostic (9.87e-3)" "unprognostic (1.14e-1)" "unprognostic (1.95e-1)" "unprognostic (5.97e-2)" "unprognostic (2.60e-2)" "unprognostic (4.29e-2)" "unprognostic (2.48e-3)" "potential prognostic unfavorable (2.15e-5)" "unprognostic (4.61e-2)" "unprognostic (1.90e-1)" "potential prognostic favorable (4.47e-4)" "unprognostic (1.78e-3)" "unprognostic (2.02e-1)" "unprognostic (1.29e-1)" "unprognostic (4.23e-2)" "unprognostic (4.00e-2)" "unprognostic (5.40e-1)" "unprognostic (1.14e-2)" "unprognostic (2.20e-1)" "unprognostic (1.58e-1)" "unprognostic (6.02e-2)" "unprognostic (8.00e-2)" "unprognostic (7.84e-2)" "unprognostic (2.27e-1)" HES7 bHLHb37 ENSG00000179111 "Hes family bHLH transcription factor 7" Q9BYE0 17 8120592-8124106 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 5.4" "Cell type enhanced" "Detected in some" "Breast hormone-responsive cells: 2.8;Breast myoepithelial cells: 3.4;Breast secretory cells: 3.9;Early spermatids: 2.2;Epididymal basal cells: 5.7;Ocular epithelial cells: 2.1;Pericytes: 3.2;Retinal amacrine cells: 2.9;Retinal bipolar cells: 2.0;Salivary duct cells: 2.0;Vascular smooth muscle cells: 3.3" "Cell type enhanced" "Detected in some" "cerebellar inhibitory: 4.4" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 23.2" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA072105 Uncertain Approved Nucleoplasm,Nucleoli No NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 15: Non-specific - Transcription" "Cluster 3: Rhabdoid - Membrane components" "Cluster 103: Non-specific - Basic cellular processes" 4 Nucleoplasm Nucleoli "HPA072105: " "unprognostic (2.66e-3)" HESX1 "ANF, RPX" ENSG00000163666 "HESX homeobox 1" Q9UBX0 3 57197838-57227606 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 76.4;Endometrial ciliated cells: 18.5;Paneth cells: 19.3;Sertoli cells: 18.7;Undifferentiated spermatogonia: 18.7" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in many" 4 "Testicular Germ Cell Tumor (TCGA): 15.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA024187 Approved Approved Nucleoplasm NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 20: Myeloma - Immune response" "Cluster 3: Early primary spermatocytes - Early meiosis" 13 Nucleoplasm "HPA024187: " "unprognostic (1.00e-1)" "potential prognostic unfavorable (8.27e-4)" "unprognostic (1.22e-1)" "unprognostic (3.16e-3)" "unprognostic (9.65e-3)" "unprognostic (3.47e-1)" "unprognostic (2.31e-1)" "unprognostic (6.39e-3)" "potential prognostic unfavorable (3.18e-5)" "unprognostic (4.55e-3)" "unprognostic (1.02e-2)" "unprognostic (3.54e-1)" "unprognostic (2.34e-1)" "unprognostic (2.51e-2)" "unprognostic (1.71e-2)" "unprognostic (2.31e-1)" "unprognostic (1.03e-1)" "unprognostic (2.35e-1)" "unprognostic (4.08e-2)" "unprognostic (9.25e-2)" "unprognostic (1.84e-2)" "unprognostic (1.29e-2)" "unprognostic (4.30e-1)" "unprognostic (1.31e-1)" "unprognostic (4.96e-3)" "unprognostic (2.66e-2)" "potential prognostic unfavorable (7.71e-4)" "unprognostic (4.84e-2)" HEXA ENSG00000213614 "Hexosaminidase subunit alpha" P06865 15 72340924-72376420 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" "Glycosidase, Hydrolase" "Disease variant, Gangliosidosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 79.2;Decidual stromal cells: 82.5;Hofbauer cells: 105.2;Microglia: 104.8;Syncytiotrophoblasts: 74.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018082, HPA054583" Supported Supported Vesicles,Cytosol "Intracellular and membrane" Enzyme NA NA 8400000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 22: Epididymis - Mixed function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 58: Non-specific - Nuclear processes" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 5 Vesicles Cytosol "HPA018082: , HPA054583: " "unprognostic (2.21e-1)" "unprognostic (2.22e-1)" "unprognostic (8.04e-2)" "potential prognostic unfavorable (3.41e-4)" "unprognostic (1.46e-1)" "unprognostic (2.34e-1)" "unprognostic (2.45e-2)" "unprognostic (8.90e-2)" "potential prognostic unfavorable (8.03e-4)" "unprognostic (3.29e-1)" "potential prognostic favorable (3.73e-6)" "unprognostic (7.42e-2)" "unprognostic (5.27e-2)" "unprognostic (3.11e-3)" "unprognostic (1.25e-2)" "unprognostic (3.28e-1)" "unprognostic (8.81e-2)" "unprognostic (8.83e-2)" "unprognostic (5.58e-2)" "unprognostic (2.44e-3)" "unprognostic (3.19e-1)" "unprognostic (1.92e-1)" "unprognostic (6.78e-2)" "unprognostic (1.46e-1)" "unprognostic (6.44e-2)" "unprognostic (3.06e-1)" "unprognostic (4.73e-2)" "unprognostic (2.16e-2)" "unprognostic (4.43e-2)" "unprognostic (1.87e-1)" "unprognostic (1.08e-1)" HEXB ENSG00000049860 "Hexosaminidase subunit beta" P07686 5 74640023-74722647 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" "Glycosidase, Hydrolase" "Disease variant, Gangliosidosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 596.9;Extravillous trophoblasts: 289.2;Hofbauer cells: 297.4;Migrating cytotrophoblasts: 367.1;Syncytiotrophoblasts: 625.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells, Breast - Fibroblasts, Lung - Macrophages, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055409, HPA056010" Enhanced "Intracellular and membrane" Enzyme NA NA 15000000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 22: Epididymis - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 34 "HPA055409: , HPA056010: " "unprognostic (3.47e-2)" "unprognostic (2.13e-1)" "unprognostic (2.26e-1)" "unprognostic (1.63e-1)" "unprognostic (7.24e-2)" "unprognostic (6.83e-2)" "unprognostic (3.53e-3)" "potential prognostic unfavorable (3.77e-4)" "unprognostic (3.07e-3)" "potential prognostic unfavorable (4.75e-7)" "unprognostic (3.53e-3)" "unprognostic (8.45e-3)" "unprognostic (4.20e-2)" "potential prognostic unfavorable (5.34e-10)" "unprognostic (2.36e-3)" "unprognostic (5.27e-1)" "unprognostic (4.51e-2)" "unprognostic (3.21e-2)" "unprognostic (3.13e-3)" "unprognostic (5.60e-3)" "unprognostic (9.29e-3)" "unprognostic (2.11e-2)" "unprognostic (4.00e-1)" "unprognostic (3.98e-1)" "unprognostic (4.08e-1)" "unprognostic (2.01e-1)" "unprognostic (1.32e-1)" "unprognostic (2.98e-2)" "unprognostic (4.15e-3)" "unprognostic (3.47e-1)" "unprognostic (2.27e-1)" HEXD "FLJ23825, HEXDC" ENSG00000169660 "Hexosaminidase D" Q8WVB3 17 82418318-82442645 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022834, HPA023379, HPA027844" Uncertain Approved "Nucleoli fibrillar center,Mitochondria" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 27: Breast cancer - Unknown function" "Cluster 7: Non-specific - Transcription" "Nucleoli fibrillar center, Mitochondria" "HPA022834: , HPA023379: , HPA027844: " "unprognostic (5.05e-2)" "unprognostic (4.24e-3)" "potential prognostic favorable (1.88e-4)" "unprognostic (1.08e-1)" "unprognostic (2.72e-1)" "unprognostic (1.47e-2)" "unprognostic (1.35e-3)" "unprognostic (3.83e-2)" "unprognostic (1.68e-1)" "validated prognostic favorable (2.60e-5)" "validated prognostic favorable (8.94e-4)" "potential prognostic favorable (1.79e-5)" "unprognostic (4.58e-2)" "unprognostic (1.73e-1)" "unprognostic (6.41e-2)" "unprognostic (3.87e-2)" "unprognostic (1.50e-3)" "unprognostic (1.19e-1)" "unprognostic (1.03e-3)" "unprognostic (6.96e-3)" "unprognostic (2.90e-2)" "unprognostic (8.45e-2)" "unprognostic (6.44e-2)" "potential prognostic favorable (2.79e-4)" "unprognostic (1.86e-1)" "potential prognostic favorable (9.28e-5)" "unprognostic (3.46e-2)" "unprognostic (4.64e-1)" "unprognostic (9.96e-2)" HEXIM1 "CLP-1, EDG1, HIS1, MAQ1" ENSG00000186834 "HEXIM P-TEFb complex subunit 1" O94992 17 45148475-45152099 "Predicted intracellular proteins" "Immunity, Innate immunity, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 270.4;Epididymal basal cells: 290.7;Megakaryocytes: 315.3;Syncytiotrophoblasts: 594.0;Tuft cells: 253.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008926, CAB011625" Supported Enhanced Nucleoplasm,Vesicles NA NA "Cluster 32: Basophils - Transcription" "Cluster 24: Non-specific - Transcription" "Cluster 44: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 65: Non-specific - Cell growth & division" 82 Nucleoplasm Vesicles "CAB011625: , HPA008926: " "unprognostic (1.67e-1)" "unprognostic (2.11e-1)" "unprognostic (4.53e-2)" "unprognostic (1.48e-2)" "unprognostic (3.15e-1)" "unprognostic (1.40e-1)" "unprognostic (1.99e-1)" "unprognostic (6.56e-2)" "unprognostic (4.47e-1)" "unprognostic (1.86e-3)" "unprognostic (3.50e-3)" "unprognostic (2.40e-3)" "unprognostic (5.88e-2)" "unprognostic (7.20e-2)" "unprognostic (1.83e-1)" "unprognostic (2.71e-2)" "unprognostic (6.35e-2)" "unprognostic (1.75e-1)" "potential prognostic favorable (3.35e-4)" "unprognostic (1.19e-1)" "unprognostic (4.09e-1)" "unprognostic (9.48e-2)" "unprognostic (2.01e-2)" "unprognostic (9.51e-3)" "unprognostic (2.87e-1)" "unprognostic (1.87e-1)" "unprognostic (3.05e-2)" "unprognostic (2.59e-1)" "unprognostic (1.57e-1)" "unprognostic (8.00e-2)" "unprognostic (2.21e-3)" HEXIM2 FLJ32384 ENSG00000168517 "HEXIM P-TEFb complex subunit 2" Q96MH2 17 45160700-45170040 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 43.5;testis: 32.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 164.0;Early spermatids: 131.7;Late primary spermatocytes: 169.2;Late spermatids: 426.1;Oocytes: 78.3;Platelets: 124.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023323, HPA028455" Enhanced Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 27: Breast cancer - Unknown function" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 65 "Nucleoplasm, Nuclear speckles" "HPA023323: , HPA028455: " "unprognostic (1.44e-1)" "unprognostic (9.73e-2)" "unprognostic (1.07e-1)" "unprognostic (9.19e-2)" "unprognostic (1.02e-2)" "unprognostic (1.15e-1)" "unprognostic (2.39e-1)" "unprognostic (8.29e-2)" "unprognostic (2.98e-2)" "unprognostic (2.80e-2)" "unprognostic (1.45e-3)" "unprognostic (1.15e-1)" "potential prognostic favorable (7.90e-5)" "unprognostic (2.12e-2)" "unprognostic (6.37e-3)" "unprognostic (1.66e-1)" "unprognostic (2.82e-1)" "unprognostic (3.16e-2)" "unprognostic (2.25e-2)" "unprognostic (2.99e-1)" "unprognostic (3.52e-2)" "unprognostic (7.13e-2)" "unprognostic (2.27e-1)" "unprognostic (2.03e-1)" "unprognostic (6.80e-2)" "unprognostic (7.88e-2)" "unprognostic (2.79e-1)" "unprognostic (9.84e-2)" "unprognostic (5.68e-1)" "unprognostic (6.19e-2)" "unprognostic (1.47e-2)" HEY1 "bHLHb31, CHF-2, CHF2, HERP2, HESR-1, HESR1, HRT-1" ENSG00000164683 "Hes related family bHLH transcription factor with YRPW motif 1" Q9Y5J3 8 79762371-79767857 "Cancer-related genes, Predicted intracellular proteins, Transcription factors, Transporters" "Notch signaling pathway, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 48.2" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 50.5;Endometrial glandular cells: 36.7;Endometrial luminal cells: 35.0;Extravillous trophoblasts: 159.6;Granulosa cells: 35.7;Mast cells: 45.4;Melanocytes: 43.7;Pituitary stem cells: 79.4;Respiratory secretory cells: 71.8;Vascular endothelial cells: 50.9" "Cell type enhanced" "Detected in many" "endothelial cell: 60.2;fibroblast: 61.6" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 97.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "neutrophil: 6.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 6.9" "Cancer enhanced" "Detected in many" "skin cancer: 35.0" "Breast - Endothelial cells, Liver - Vascular endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055599, HPA063472" Uncertain Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 73: Brain - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 22 Nucleoplasm "Nuclear membrane, Cytosol" "HPA055599: , HPA063472: " "unprognostic (2.10e-3)" "unprognostic (1.77e-1)" "unprognostic (2.56e-1)" "unprognostic (5.08e-2)" "unprognostic (6.44e-3)" "unprognostic (3.62e-2)" "validated prognostic favorable (9.45e-4)" "validated prognostic favorable (3.37e-4)" "unprognostic (7.46e-2)" "unprognostic (9.92e-2)" "validated prognostic favorable (1.86e-5)" "validated prognostic favorable (4.57e-4)" "unprognostic (5.85e-3)" "unprognostic (1.58e-2)" "unprognostic (6.32e-2)" "unprognostic (1.17e-1)" "unprognostic (1.82e-1)" "unprognostic (1.97e-2)" "unprognostic (1.74e-1)" "unprognostic (2.89e-1)" "unprognostic (1.34e-2)" "unprognostic (2.27e-3)" "unprognostic (1.22e-2)" "unprognostic (2.27e-3)" "unprognostic (2.26e-2)" "unprognostic (4.51e-2)" "unprognostic (5.56e-2)" "unprognostic (1.67e-2)" "unprognostic (3.21e-1)" "unprognostic (2.59e-2)" "unprognostic (2.68e-1)" HEY2 "bHLHb32, HERP1, HESR2" ENSG00000135547 "Hes related family bHLH transcription factor with YRPW motif 2" Q9UBP5 6 125747664-125761269 "Predicted intracellular proteins, Transcription factors, Transporters" "Notch signaling pathway, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 70.9;heart muscle: 29.1" "Cell type enhanced" "Detected in many" "Bergmann glia: 54.8;Cardiomyocytes: 156.2;Endometrial luminal cells: 67.0;Epididymal principal cells: 76.9;Fallopian tube ciliated cells: 57.5;Granulosa cells: 164.6;Late primary spermatocytes: 53.8;Late spermatids: 104.8;Müller glia: 68.8;Oocytes: 101.3;Pituitary stem cells: 62.8;Vascular smooth muscle cells: 110.7" "Cell type enhanced" "Detected in many" "astrocyte: 79.8;pericyte: 151.4;vascular associated smooth muscle cell: 231.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Heart muscle - Cardiomyocytes, Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030205, HPA074851" Approved Approved "Nuclear bodies,Aggresome" NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 62: Smooth muscle cells - Muscle contraction" 31 "Nuclear bodies" Aggresome "HPA030205: , HPA074851: " "unprognostic (1.44e-1)" "unprognostic (1.11e-1)" "potential prognostic unfavorable (5.01e-5)" "unprognostic (1.37e-2)" "unprognostic (1.01e-2)" "unprognostic (2.24e-2)" "unprognostic (1.16e-1)" "unprognostic (7.76e-3)" "unprognostic (5.35e-3)" "unprognostic (8.98e-2)" "validated prognostic favorable (1.04e-4)" "validated prognostic favorable (1.18e-5)" "unprognostic (1.70e-3)" "unprognostic (2.63e-1)" "potential prognostic favorable (9.66e-4)" "unprognostic (7.50e-2)" "unprognostic (2.59e-1)" "unprognostic (5.97e-2)" "unprognostic (1.97e-1)" "unprognostic (8.68e-2)" "unprognostic (1.73e-1)" "unprognostic (1.17e-1)" "unprognostic (8.09e-2)" "unprognostic (6.42e-2)" "unprognostic (9.14e-2)" "unprognostic (4.39e-3)" "unprognostic (2.51e-1)" "unprognostic (6.12e-2)" "unprognostic (8.23e-2)" "unprognostic (1.31e-3)" "unprognostic (5.38e-2)" HEYL "bHLHb33, HESR3, HEY3" ENSG00000163909 "Hes related family bHLH transcription factor with YRPW motif like" Q9NQ87 1 39623435-39639643 "Predicted intracellular proteins, Transcription factors" "Notch signaling pathway, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 81.1;pancreas: 65.5" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 31.9;Granulosa cells: 77.0;Hepatic stellate cells: 45.2;Leydig cells: 59.3;Myosatellite cells: 71.8;Pancreatic acinar cells: 56.9;Pericytes: 147.3;Peritubular myoid cells: 124.8;Rod photoreceptor cells: 32.4;Sertoli cells: 41.3;Vascular smooth muscle cells: 181.7" "Group enriched" "Detected in some" 6 "pericyte: 81.3;vascular associated smooth muscle cell: 127.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 13.8" "Adrenal gland - Fibroblasts, Breast - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA000970, HPA076960" Approved Approved "Nucleoli fibrillar center" NA NA "Cluster 70: Non-specific - Protein processing" "Cluster 46: Brainstem - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 110: Mural cells - ECM organization" 9 "Nucleoli fibrillar center" "HPA000970: , HPA076960: " "unprognostic (2.60e-1)" "unprognostic (2.31e-2)" "unprognostic (3.70e-2)" "unprognostic (5.65e-2)" "potential prognostic unfavorable (3.18e-5)" "unprognostic (1.31e-3)" "unprognostic (1.83e-1)" "unprognostic (3.62e-2)" "unprognostic (1.63e-1)" "unprognostic (1.02e-1)" "unprognostic (2.60e-2)" "unprognostic (8.35e-3)" "potential prognostic unfavorable (4.53e-5)" "unprognostic (1.06e-1)" "unprognostic (7.98e-2)" "unprognostic (7.32e-2)" "unprognostic (1.14e-2)" "unprognostic (1.47e-2)" "unprognostic (2.08e-2)" "unprognostic (1.24e-2)" "unprognostic (7.58e-3)" "unprognostic (2.42e-1)" "unprognostic (5.85e-1)" "unprognostic (2.09e-1)" "unprognostic (3.81e-1)" "unprognostic (4.55e-2)" "unprognostic (4.43e-3)" "unprognostic (2.64e-3)" "unprognostic (2.94e-2)" "unprognostic (1.08e-1)" "unprognostic (1.07e-1)" HFE "HFE1, HLA-H" ENSG00000010704 "Homeostatic iron regulator" Q30201 6 26087281-26098343 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Ion transport, Iron transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hofbauer cells: 27.7;Kupffer cells: 74.8;Platelets: 22.6" "Cell type enhanced" "Detected in many" "fibroblast: 13.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017276, HPA053470" Approved Supported "Nucleoplasm,Plasma membrane" No No "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 22: Epididymis - Mixed function" "Cluster 36: Choroid plexus - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 6 "Plasma membrane" Nucleoplasm "HPA017276: , HPA053470: " "unprognostic (3.17e-2)" "unprognostic (6.59e-2)" "unprognostic (2.24e-1)" "unprognostic (1.36e-2)" "unprognostic (6.18e-2)" "unprognostic (1.08e-1)" "unprognostic (6.94e-3)" "potential prognostic unfavorable (7.65e-7)" "unprognostic (6.50e-2)" "unprognostic (9.88e-2)" "potential prognostic favorable (1.21e-5)" "unprognostic (9.40e-3)" "unprognostic (2.48e-1)" "unprognostic (2.91e-1)" "unprognostic (2.46e-1)" "unprognostic (9.41e-2)" "unprognostic (5.08e-2)" "unprognostic (3.75e-1)" "unprognostic (1.30e-1)" "unprognostic (1.86e-1)" "unprognostic (2.77e-2)" "unprognostic (2.01e-3)" "unprognostic (1.33e-1)" "unprognostic (2.69e-1)" "unprognostic (1.90e-1)" "unprognostic (2.60e-1)" "unprognostic (8.32e-3)" "unprognostic (1.12e-1)" "unprognostic (2.38e-1)" "unprognostic (5.95e-2)" "unprognostic (9.67e-2)" HFM1 "FLJ36760, FLJ39011, MER3, SEC63D1" ENSG00000162669 "Helicase for meiosis 1" A2PYH4 1 91260766-91404856 "Enzymes, Human disease related genes, Predicted intracellular proteins" Meiosis "Helicase, Hydrolase, Isomerase" "Disease variant, Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 8.7;testis: 12.9" "Cell type enhanced" "Detected in many" "Bergmann glia: 82.8;Corticotrophs: 487.7;Early primary spermatocytes: 172.7;Gonadotrophs: 81.4;Myonuclei: 122.9;Oligodendrocyte progenitor cells: 120.2;Pituicytes/FSCs: 80.8;Podocytes: 104.5;Sertoli cells: 100.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in single" "Testicular Germ Cell Tumor (TCGA): 1.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 1.9" "Heart muscle - Cardiomyocytes, Pituitary gland - Corticotropes, Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA035036, HPA035557" Supported "Golgi apparatus,Vesicles" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 2: Neurons - Nucleosome" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 55: Myocytes - Oxidative muscle function" "Golgi apparatus, Vesicles" "HPA035036: , HPA035557: " "unprognostic (3.08e-3)" "unprognostic (1.28e-1)" HGD "AKU, HGO" ENSG00000113924 "Homogentisate 1,2-dioxygenase" Q93099 3 120628172-120682269 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Phenylalanine catabolism, Tyrosine catabolism" "Dioxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "kidney: 186.7;liver: 703.2" "Cell type enhanced" "Detected in many" "Cholangiocytes: 99.7;Endometrial ciliated cells: 130.9;Endometrial glandular cells: 164.2;Endometrial luminal cells: 179.8;Hepatocytes: 734.0;Neuroendocrine cells: 93.1;Platelets: 143.5;Prostatic glandular cells: 106.8;Proximal tubule cells: 185.9;Renal collecting duct intercalated cells: 123.8" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 7.1" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 294.2" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 6 "neutrophil: 1.1" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.1" "Cancer enhanced" "Detected in many" "Kidney cancer: 42.7;liver cancer: 42.4" "Breast - Breast glandular cells, Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA047374, HPA052359" Enhanced Approved "Golgi apparatus" NA NA 1100000 "Cluster 28: Neutrophils - Unknown function" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 2 "Golgi apparatus" "HPA047374: , HPA052359: " "unprognostic (9.55e-2)" "unprognostic (2.99e-2)" "unprognostic (1.26e-2)" "unprognostic (5.56e-2)" "unprognostic (9.65e-2)" "unprognostic (1.17e-1)" "unprognostic (2.47e-2)" "unprognostic (9.70e-2)" "potential prognostic favorable (5.41e-5)" "unprognostic (1.22e-1)" "unprognostic (1.10e-1)" "unprognostic (1.35e-2)" "potential prognostic favorable (5.41e-5)" "unprognostic (1.67e-2)" "unprognostic (6.29e-2)" "unprognostic (6.50e-3)" "unprognostic (7.38e-3)" "unprognostic (4.15e-3)" "unprognostic (1.27e-1)" "unprognostic (4.72e-2)" "unprognostic (4.39e-2)" "unprognostic (3.16e-1)" "unprognostic (1.69e-2)" "potential prognostic unfavorable (7.14e-4)" "unprognostic (6.62e-2)" "unprognostic (4.83e-3)" "unprognostic (6.25e-2)" HGF "DFNB39, F-TCF, HGFB, HPTA, SF" ENSG00000019991 "Hepatocyte growth factor" P14210 7 81699010-81770438 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Serine protease homolog" "Cancer-related genes, Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "placenta: 292.9" "Cell type enhanced" "Detected in many" "Fibroblasts: 109.9;Hepatic stellate cells: 290.5;Monocyte progenitors: 114.2;Müller glia: 49.5;Pericytes: 145.1;Schwann cells: 93.0;Smooth muscle cells: 40.7;Vascular smooth muscle cells: 39.8" "Cell type enhanced" "Detected in many" "MGE interneuron: 71.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 94.6" "Lineage enriched" "Detected in many" 5 "granulocytes: 94.6" "Cancer enhanced" "Detected in many" "Neuroblastoma: 101.3;Rhabdoid: 247.7" "Adrenal gland - Fibroblasts, Kidney - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB010333, HPA040360, HPA044088" Approved "Secreted to blood" "Growth factor" NA NA 4110000 5600000 "Cluster 46: Basophils - Proteolysis" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 24: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 108: Fibroblasts - ECM organization" 5 "CAB010333: , HPA040360: , HPA044088: " "unprognostic (6.64e-2)" "unprognostic (5.83e-2)" "unprognostic (1.55e-1)" "unprognostic (1.06e-1)" "unprognostic (1.14e-1)" "unprognostic (6.98e-2)" "unprognostic (3.61e-2)" "unprognostic (1.38e-2)" "unprognostic (4.04e-3)" "unprognostic (1.22e-1)" "unprognostic (2.65e-3)" "unprognostic (9.38e-2)" "unprognostic (1.20e-1)" "unprognostic (2.46e-1)" "unprognostic (1.25e-3)" "unprognostic (1.29e-3)" "unprognostic (1.28e-1)" "unprognostic (1.06e-3)" "unprognostic (2.36e-2)" "potential prognostic unfavorable (2.04e-4)" "unprognostic (3.03e-1)" "unprognostic (1.19e-1)" "unprognostic (3.72e-1)" "unprognostic (2.86e-1)" "unprognostic (2.41e-1)" "unprognostic (4.42e-3)" "unprognostic (1.21e-2)" "unprognostic (8.62e-3)" "unprognostic (1.41e-1)" HGFAC "HGFA, HGFAP" ENSG00000109758 "HGF activator" Q04756 4 3441968-3449486 "Cancer-related genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 57 "liver: 223.6" "Cell type enhanced" "Detected in some" "Early spermatids: 88.4;Epididymal efferent duct absorptive cells: 22.5;Epididymal efferent duct ciliated cells: 30.2;Hepatocytes: 91.1;Late primary spermatocytes: 90.7;Late spermatids: 207.0" "Cell type enriched" "Detected in some" 8 "CGE interneuron: 16.0" "Cancer enriched" "Detected in some" 8 "Liver Hepatocellular Carcinoma (TCGA): 34.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "thyroid cancer: 1.1" "Breast - Breast glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA058279, HPA059076" Enhanced "Secreted to blood" Enzyme NA NA 7590000 2700000000 "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 48: Non-specific - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 5 "HPA058279: , HPA059076: " "unprognostic (1.25e-1)" "unprognostic (7.19e-2)" "unprognostic (3.67e-3)" "potential prognostic favorable (5.10e-4)" "unprognostic (4.66e-2)" HGH1 "Brp16, C8orf30A, C8orf30B, FAM203A, FAM203B, FLJ40907, LOC51236" ENSG00000235173 "HGH1 homolog" Q9BTY7 8 144137774-144140851 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 23.1;Late primary spermatocytes: 28.2;Late spermatids: 43.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 18.1;Stomach Adenocarcinoma (TCGA): 16.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042470 Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 5 "Nuclear bodies, Cytosol" Nucleoplasm "HPA042470: " "unprognostic (3.31e-2)" "unprognostic (4.56e-3)" "unprognostic (8.06e-3)" "unprognostic (1.52e-1)" "unprognostic (1.15e-1)" "unprognostic (6.95e-3)" "unprognostic (2.29e-2)" "unprognostic (4.11e-2)" "unprognostic (3.40e-1)" "unprognostic (2.91e-1)" "unprognostic (7.83e-2)" "unprognostic (1.00e-2)" "unprognostic (6.57e-2)" "unprognostic (1.79e-2)" "unprognostic (8.23e-2)" "unprognostic (1.24e-1)" "unprognostic (8.55e-2)" "unprognostic (1.30e-1)" "unprognostic (2.60e-1)" "unprognostic (4.24e-1)" "unprognostic (1.95e-2)" "unprognostic (3.37e-1)" "unprognostic (5.91e-2)" "unprognostic (7.01e-2)" "unprognostic (1.29e-1)" "unprognostic (1.27e-1)" "unprognostic (9.90e-2)" HGS "Hrs, Vps27, ZFYVE8" ENSG00000185359 "Hepatocyte growth factor-regulated tyrosine kinase substrate" O14964 17 81683326-81703138 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 160.2;Late spermatids: 230.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004872, HPA007728" Uncertain Approved Endosomes,Lysosomes,Cytosol NA NA 10000 "Cluster 28: Neutrophils - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 303 "Endosomes, Lysosomes" Cytosol "HPA004872: , HPA007728: " "unprognostic (2.88e-1)" "unprognostic (3.31e-1)" "unprognostic (3.56e-2)" "unprognostic (1.30e-1)" "unprognostic (2.30e-1)" "unprognostic (4.65e-2)" "unprognostic (7.64e-2)" "unprognostic (4.76e-3)" "unprognostic (3.99e-2)" "unprognostic (1.52e-1)" "potential prognostic unfavorable (1.04e-6)" "unprognostic (2.23e-3)" "unprognostic (1.92e-1)" "potential prognostic unfavorable (2.48e-4)" "unprognostic (1.21e-3)" "unprognostic (9.50e-3)" "unprognostic (1.72e-3)" "unprognostic (8.67e-2)" "unprognostic (1.67e-2)" "unprognostic (1.10e-1)" "unprognostic (1.01e-2)" "unprognostic (2.14e-1)" "unprognostic (2.28e-2)" "unprognostic (1.93e-1)" "unprognostic (3.38e-1)" "unprognostic (1.78e-1)" "unprognostic (2.62e-1)" "unprognostic (3.69e-1)" "unprognostic (2.63e-1)" "unprognostic (3.34e-2)" "unprognostic (8.94e-2)" HGSNAT "FLJ32731, HGNAT, TMEM76" ENSG00000165102 "Heparan-alpha-glucosaminide N-acetyltransferase" Q68CP4 8 43140464-43202855 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Acyltransferase, Transferase" "Disease variant, Mucopolysaccharidosis, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Lactotrophs: 362.5;Somatotrophs: 354.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029578 Approved NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 75: Ovary - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 27: Breast cancer - Unknown function" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" "HPA029578: " "unprognostic (2.54e-2)" "unprognostic (2.08e-1)" "unprognostic (1.83e-1)" "unprognostic (1.62e-2)" "unprognostic (1.95e-1)" "unprognostic (1.97e-1)" "unprognostic (1.77e-2)" "unprognostic (2.41e-1)" "unprognostic (2.78e-3)" "unprognostic (2.57e-2)" "potential prognostic favorable (3.39e-6)" "unprognostic (7.99e-2)" "unprognostic (3.24e-1)" "unprognostic (6.26e-2)" "unprognostic (1.25e-1)" "unprognostic (1.28e-2)" "unprognostic (1.23e-1)" "unprognostic (5.18e-2)" "unprognostic (1.54e-1)" "unprognostic (5.02e-3)" "unprognostic (4.60e-2)" "unprognostic (1.08e-2)" "unprognostic (1.24e-1)" "unprognostic (4.02e-2)" "unprognostic (1.26e-1)" "unprognostic (2.35e-1)" "unprognostic (1.20e-1)" "unprognostic (3.26e-3)" "unprognostic (6.99e-2)" "unprognostic (5.35e-2)" "unprognostic (8.37e-2)" HHAT "FLJ10724, GUP2, MART-2, MART2, rasp, sit, ski, Skn" ENSG00000054392 "Hedgehog acyltransferase" Q5VTY9 1 210328252-210676296 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Acyltransferase, Developmental protein, Transferase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 42.2;Choroid plexus epithelial cells: 146.4;Distal convoluted tubule cells: 99.8;Ependymal cells: 162.0;Loop of henle epithelial cells: 52.5;Papillary tip epithelial cells: 57.3;Podocytes: 29.9;Proximal tubule cells: 31.8;Renal collecting duct intercalated cells: 46.5;Renal collecting duct principal cells: 52.9;Renal connecting tubule cells: 68.5" "Cell type enhanced" "Detected in all" "ependymal cell: 154.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 3.7" "Group enriched" "Detected in many" 5 "B-cells: 1.8;dendritic cells: 3.7;T-cells: 1.3" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Kidney - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Outer root sheath cells, Testis - Sertoli cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA016462 Approved Approved "Golgi apparatus" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 20: Pituitary gland - Hormone signaling" "Cluster 23: Choroid plexus - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 34: Ciliated cells - Cilia assembly & function" 1 "Golgi apparatus" "HPA016462: " "unprognostic (4.58e-3)" "unprognostic (2.48e-1)" "unprognostic (5.09e-2)" "unprognostic (8.31e-2)" "unprognostic (1.43e-1)" "unprognostic (1.12e-1)" "unprognostic (5.56e-2)" "unprognostic (1.32e-2)" "unprognostic (5.43e-2)" "unprognostic (1.95e-1)" "potential prognostic favorable (3.29e-6)" "unprognostic (1.35e-2)" "unprognostic (8.23e-3)" "unprognostic (3.36e-2)" "unprognostic (1.01e-1)" "unprognostic (7.10e-2)" "unprognostic (3.68e-1)" "unprognostic (1.28e-1)" "unprognostic (1.23e-1)" "unprognostic (6.16e-2)" "unprognostic (4.69e-2)" "unprognostic (2.42e-1)" "unprognostic (1.26e-1)" "unprognostic (1.13e-1)" "unprognostic (1.01e-2)" "unprognostic (1.59e-2)" "unprognostic (2.42e-1)" "unprognostic (7.33e-2)" "unprognostic (2.12e-1)" "unprognostic (6.98e-2)" "unprognostic (2.29e-1)" HHATL "C3orf3, GUP1, KIAA1173, MBOAT3, MSTP002, OACT3" ENSG00000010282 "Hedgehog acyltransferase like" Q9HCP6 3 42692663-42702824 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "brain: 233.4;heart muscle: 487.7;skeletal muscle: 264.6;tongue: 144.0" "Cell type enhanced" "Detected in some" "Astrocytes: 59.8;Cardiomyocytes: 16.8;Ependymal cells: 12.7;Melanocytes: 33.0;Müller glia: 40.9;Myonuclei: 32.1;Oligodendrocytes: 72.7;Retinal bipolar cells: 70.1;Retinal pigment epithelial cells: 12.8;Thymic myoid cells: 39.4" "Group enriched" "Detected in many" 5 "astrocyte: 61.7;oligodendrocyte: 110.4" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 35.4;Skin Cutaneous Melanoma (TCGA): 33.2;Thyroid Carcinoma (TCGA): 53.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 15 "thyroid cancer: 4.6" "Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Pancreas - Beta cells, Pituitary gland - Corticotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018174 Enhanced NA NA "Cluster 41: Striated muscle - Muscle contraction" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 13 "HPA018174: " "unprognostic (8.88e-2)" "unprognostic (3.34e-1)" "unprognostic (2.71e-3)" "unprognostic (4.41e-1)" "unprognostic (1.32e-1)" "unprognostic (4.22e-1)" "unprognostic (3.00e-1)" "unprognostic (1.20e-3)" "unprognostic (7.65e-3)" "unprognostic (3.97e-1)" "unprognostic (4.45e-1)" "unprognostic (1.26e-1)" HHEX "HEX, HOX11L-PEN, PRHX" ENSG00000152804 "Hematopoietically expressed homeobox" Q03014 10 92689955-92695647 "Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation, Wnt signaling pathway" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 80.0;liver: 88.1;thyroid gland: 97.2" "Cell type enhanced" "Detected in many" "B-cells: 52.5;Cholangiocytes: 144.8;Hematopoietic stem cells: 65.5;Hepatocytes: 65.9;Hofbauer cells: 139.0;Kupffer cells: 63.5;Lymphatic endothelial cells: 73.0;Megakaryocyte-Erythroid progenitors: 58.6;Monocyte progenitors: 61.1;Neutrophil progenitors: 49.6;Neutrophils: 50.0;Oocytes: 92.1;Pancreatic duct cells: 158.1;Platelets: 155.5;Vascular endothelial cells: 57.7" "Group enriched" "Detected in some" 6 "central nervous system macrophage: 34.4;endothelial cell: 34.8" "Group enriched" "Detected in all" 5 "Liver Hepatocellular Carcinoma (TCGA): 38.9;Thyroid Carcinoma (TCGA): 130.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 43 "basophil: 28.0;classical monocyte: 41.5;eosinophil: 61.9;intermediate monocyte: 45.7;memory B-cell: 59.5;myeloid DC: 30.9;naive B-cell: 66.0;neutrophil: 31.6;non-classical monocyte: 50.9;plasmacytoid DC: 36.4" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Leukemia: 68.9" "Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "HPA003257, HPA051894" Approved Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 47: Endothelial cells - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 27 Nucleoplasm "Nuclear bodies" "HPA003257: , HPA051894: " "unprognostic (6.41e-3)" "unprognostic (5.35e-3)" "unprognostic (4.95e-3)" "unprognostic (1.16e-3)" "unprognostic (2.95e-1)" "unprognostic (8.27e-2)" "unprognostic (2.96e-1)" "unprognostic (8.14e-2)" "unprognostic (6.66e-3)" "unprognostic (4.94e-2)" "unprognostic (8.46e-3)" "unprognostic (1.88e-2)" "unprognostic (2.26e-2)" "potential prognostic unfavorable (1.75e-4)" "unprognostic (4.38e-2)" "unprognostic (8.85e-3)" "unprognostic (1.61e-1)" "unprognostic (7.35e-2)" "unprognostic (6.39e-2)" "unprognostic (2.50e-1)" "unprognostic (4.33e-2)" "unprognostic (2.83e-3)" "unprognostic (2.25e-1)" "unprognostic (3.05e-1)" "unprognostic (3.27e-2)" "unprognostic (2.23e-1)" "unprognostic (1.24e-1)" "unprognostic (7.47e-2)" "unprognostic (9.94e-2)" "unprognostic (1.51e-1)" "unprognostic (2.15e-2)" HHIP "FLJ20992, HIP" ENSG00000164161 "Hedgehog interacting protein" Q96QV1 4 144646156-144745271 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 8.4;lung: 15.3" "Group enriched" "Detected in many" 4 "Alveolar cells type 2: 466.2;Leydig cells: 360.6;Oligodendrocytes: 654.8" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 281.6;oligodendrocyte: 731.0" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 4.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Rhabdoid: 115.1" "Adipose visceral - Mesothelial cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Alveolar cells type 2, Minor Salivary Gland - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012616 Uncertain Uncertain Nucleoplasm "Secreted in other tissues" "No annotated function" NA NA 280000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 5: Rhabdoid - Unknown function" "Cluster 80: Oligodendrocytes - Myelination" 1 Nucleoplasm "HPA012616: " "unprognostic (1.87e-1)" "unprognostic (1.15e-1)" "unprognostic (4.44e-1)" "unprognostic (3.74e-2)" "unprognostic (8.82e-2)" "unprognostic (6.31e-2)" "unprognostic (1.16e-2)" "unprognostic (3.05e-2)" "unprognostic (2.30e-2)" "unprognostic (1.58e-2)" "unprognostic (2.32e-1)" "unprognostic (4.62e-2)" "unprognostic (3.26e-2)" "unprognostic (1.95e-2)" "unprognostic (1.17e-1)" "unprognostic (2.01e-1)" HHIPL1 KIAA1822 ENSG00000182218 "HHIP like 1" Q96JK4 14 99645129-99680569 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 9.5" "Cell type enhanced" "Detected in some" "Astrocytes: 39.4;Bergmann glia: 21.0;Brain inhibitory neurons: 11.1;Ependymal cells: 12.0;Mesothelial cells: 14.4;Microglia: 10.3;Müller glia: 23.4;Oligodendrocyte progenitor cells: 11.5;Retinal amacrine cells: 28.1;Retinal bipolar cells: 19.3;Retinal horizontal cells: 10.0;Retinal pigment epithelial cells: 12.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "thyroid cancer: 2.2" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblasts_2, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in many" "Secreted in other tissues" "No annotated function" NA NA 72000 "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "unprognostic (2.69e-1)" "unprognostic (2.32e-1)" "unprognostic (2.89e-1)" "unprognostic (6.95e-2)" "unprognostic (2.44e-1)" "unprognostic (2.27e-1)" "unprognostic (3.81e-2)" "unprognostic (3.30e-3)" "potential prognostic unfavorable (8.86e-4)" "unprognostic (2.52e-1)" "unprognostic (2.93e-1)" "unprognostic (1.17e-2)" "unprognostic (1.72e-2)" "unprognostic (2.76e-2)" "unprognostic (4.17e-3)" "unprognostic (1.31e-1)" HHIPL2 "FLJ13840, KIAA1822L" ENSG00000143512 "HHIP like 2" Q6UWX4 1 222522258-222548104 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 4.5;thyroid gland: 1.9" "Group enriched" "Detected in some" 4 "Early spermatids: 24.1;Late primary spermatocytes: 34.0;Late spermatids: 42.2" "Cell type enhanced" "Detected in some" "endothelial cell: 2.2" "Cancer enhanced" "Detected in some" "Lung Adenocarcinoma (TCGA): 4.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA059673 Enhanced Uncertain Mitochondria,Cytosol "Secreted in other tissues" "No annotated function" No NA "Cluster 21: Testis - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 1 Mitochondria Cytosol "HPA059673: " "unprognostic (1.34e-3)" "unprognostic (1.25e-1)" "unprognostic (3.06e-1)" "unprognostic (1.49e-2)" "unprognostic (1.59e-1)" "potential prognostic unfavorable (4.50e-4)" "unprognostic (2.07e-2)" "unprognostic (6.11e-2)" "potential prognostic unfavorable (9.51e-4)" HHLA1 PLA2L ENSG00000132297 "HERV-H LTR-associating 1" C9JL84 8 132061480-132111159 "Predicted secreted proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 1.1;Brain inhibitory neurons: 1.4;Melanocytes: 2.0;Other brain neurons: 2.3" "Cell type enhanced" "Detected in many" "thalamic excitatory: 7.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted - unknown location" "No annotated function" NA NA "Cluster 34: Testis cancer - Unknown function" "Cluster 109: Neurons - Neuronal signaling" "unprognostic (9.04e-2)" "unprognostic (2.76e-3)" HHLA2 "B7-H5, B7-H7, B7H7, B7y" ENSG00000114455 "HERV-H LTR-associating 2" Q9UM44 3 108296529-108378285 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "intestine: 129.9" "Group enriched" "Detected in many" 4 "Colonocytes: 491.1;Enterocytes: 691.1;Respiratory ciliated cells: 234.1" "Cell type enhanced" "Detected in many" "ependymal cell: 11.9" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 49.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.1" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "colorectal cancer: 12.4;Rhabdoid: 15.4" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" HPA055478 Enhanced NA NA "Cluster 77: Intestine - Digestion" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 13 "HPA055478: " "unprognostic (1.26e-2)" "unprognostic (6.40e-3)" "unprognostic (2.23e-1)" "potential prognostic favorable (2.09e-5)" "unprognostic (1.56e-1)" "potential prognostic favorable (4.40e-8)" "unprognostic (1.36e-2)" "unprognostic (4.07e-2)" "unprognostic (7.20e-3)" "unprognostic (2.19e-1)" "unprognostic (7.24e-3)" "unprognostic (3.81e-1)" "unprognostic (4.72e-2)" "unprognostic (1.37e-3)" "unprognostic (2.10e-3)" "unprognostic (8.04e-2)" "unprognostic (3.78e-3)" "unprognostic (9.63e-2)" "unprognostic (2.97e-1)" "unprognostic (1.76e-1)" "unprognostic (4.10e-2)" HIBADH NS5ATP1 ENSG00000106049 "3-hydroxyisobutyrate dehydrogenase" P31937 7 27525442-27662883 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Branched-chain amino acid catabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 633.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019522, HPA021002" Enhanced NA NA 840000 "Cluster 33: Non-specific - ATP binding" "Cluster 76: Non-specific - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 35 "HPA019522: , HPA021002: " "unprognostic (3.24e-2)" "unprognostic (1.62e-2)" "unprognostic (1.04e-1)" "unprognostic (1.85e-3)" "unprognostic (3.78e-2)" "unprognostic (3.27e-1)" "unprognostic (1.91e-1)" "unprognostic (1.07e-1)" "unprognostic (1.51e-2)" "unprognostic (2.77e-2)" "potential prognostic favorable (1.21e-11)" "unprognostic (1.58e-2)" "unprognostic (2.46e-3)" "unprognostic (6.82e-2)" "unprognostic (1.74e-1)" "potential prognostic unfavorable (1.43e-4)" "unprognostic (1.36e-1)" "unprognostic (1.26e-1)" "unprognostic (4.06e-1)" "unprognostic (1.33e-1)" "unprognostic (1.15e-2)" "unprognostic (7.08e-2)" "unprognostic (6.81e-2)" "unprognostic (1.22e-1)" "unprognostic (4.53e-3)" "unprognostic (4.71e-2)" "unprognostic (1.67e-2)" "unprognostic (1.90e-1)" "unprognostic (4.12e-1)" "unprognostic (2.44e-1)" "unprognostic (1.62e-1)" HIBCH ENSG00000198130 "3-hydroxyisobutyryl-CoA hydrolase" Q6NVY1 2 190189735-190344193 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Branched-chain amino acid catabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Sertoli cells: 572.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036540, HPA036541, HPA067080" Enhanced Enhanced Mitochondria NA NA 270000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 76: Non-specific - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 2 Mitochondria "HPA036540: , HPA036541: , HPA067080: " "unprognostic (5.36e-3)" "unprognostic (2.78e-3)" "unprognostic (2.58e-2)" "unprognostic (1.82e-1)" "unprognostic (1.53e-1)" "unprognostic (1.39e-3)" "unprognostic (8.86e-2)" "unprognostic (2.31e-1)" "unprognostic (1.20e-2)" "unprognostic (1.10e-1)" "validated prognostic favorable (1.69e-8)" "validated prognostic favorable (4.80e-4)" "unprognostic (3.00e-2)" "unprognostic (2.07e-1)" "unprognostic (1.53e-1)" "unprognostic (6.13e-2)" "unprognostic (9.84e-3)" "unprognostic (2.14e-1)" "unprognostic (3.30e-1)" "unprognostic (5.55e-2)" "unprognostic (2.57e-1)" "unprognostic (6.84e-2)" "unprognostic (2.35e-1)" "unprognostic (6.22e-2)" "unprognostic (1.94e-2)" "unprognostic (2.09e-1)" "unprognostic (9.69e-3)" "unprognostic (3.36e-1)" "unprognostic (3.38e-1)" "unprognostic (4.14e-1)" "unprognostic (9.61e-2)" HIC1 "ZBTB29, ZNF901" ENSG00000177374 "HIC ZBTB transcriptional repressor 1" Q14526 17 2054154-2063241 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Developmental protein, DNA-binding, Repressor" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 35.3;Endometrial stromal cells: 33.9;Epicardial cells: 31.8;Fibro-adipogenic progenitors: 23.5;Fibroblasts: 55.5;Hepatic stellate cells: 32.3;Innate lymphoid cells: 27.0;Leydig cells: 63.9;Lymphatic endothelial cells: 39.5;Ovarian stromal cells: 21.5;Pericytes: 66.5;Peritubular myoid cells: 52.1;Vascular endothelial cells: 21.4" "Group enriched" "Detected in some" 4 "fibroblast: 60.5;pericyte: 102.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 1.9" "Lineage enhanced" "Detected in single" "granulocytes: 1.9" "Cancer enhanced" "Detected in many" "Rhabdoid: 14.2" "Prostate - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA043372 Uncertain NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 110: Mural cells - ECM organization" 22 "HPA043372: " "unprognostic (7.81e-2)" "unprognostic (9.27e-2)" "unprognostic (1.44e-1)" "unprognostic (1.42e-2)" "unprognostic (6.53e-3)" "unprognostic (2.17e-1)" "unprognostic (5.86e-2)" "unprognostic (4.50e-1)" "unprognostic (1.01e-1)" "unprognostic (1.17e-1)" "unprognostic (1.86e-1)" "unprognostic (2.85e-2)" "unprognostic (1.39e-3)" "unprognostic (3.70e-1)" "unprognostic (2.89e-2)" "unprognostic (9.09e-2)" "unprognostic (5.97e-2)" "unprognostic (4.57e-2)" "unprognostic (3.77e-2)" "unprognostic (1.56e-2)" "unprognostic (2.27e-2)" "unprognostic (4.26e-2)" "unprognostic (4.97e-1)" "unprognostic (1.45e-2)" "unprognostic (2.42e-1)" "unprognostic (2.64e-2)" "unprognostic (4.47e-2)" "unprognostic (3.52e-2)" "unprognostic (1.83e-2)" "unprognostic (2.87e-2)" "unprognostic (1.02e-2)" HIC2 "HRG22, KIAA1020, ZBTB30, ZNF907" ENSG00000169635 "HIC ZBTB transcriptional repressor 2" Q96JB3 22 21417371-21451463 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 49.6;Extravillous trophoblasts: 52.1;Late spermatids: 52.0;Migrating cytotrophoblasts: 47.3;Renal collecting duct intercalated cells: 36.8;Syncytiotrophoblasts: 45.8" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 4 "Testicular Germ Cell Tumor (TCGA): 30.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA031884, HPA059399" Uncertain Supported Nucleoplasm NA NA "Cluster 67: Testis - Mixed function" "Cluster 33: Neurons - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 11 Nucleoplasm "HPA031884: , HPA059399: " "unprognostic (3.02e-1)" "unprognostic (7.59e-2)" "unprognostic (7.18e-2)" "unprognostic (1.50e-2)" "unprognostic (7.53e-2)" "unprognostic (2.63e-1)" "unprognostic (1.63e-1)" "unprognostic (5.91e-3)" "unprognostic (1.48e-1)" "unprognostic (1.84e-1)" "potential prognostic favorable (1.22e-4)" "unprognostic (4.74e-3)" "unprognostic (1.13e-1)" "unprognostic (9.87e-3)" "unprognostic (1.50e-3)" "unprognostic (8.40e-2)" "unprognostic (1.91e-1)" "potential prognostic favorable (6.47e-5)" "unprognostic (6.39e-2)" "unprognostic (3.14e-2)" "unprognostic (1.21e-3)" "potential prognostic unfavorable (3.06e-4)" "unprognostic (1.45e-1)" "unprognostic (1.54e-2)" "unprognostic (2.40e-3)" "unprognostic (1.84e-2)" "unprognostic (1.65e-1)" "unprognostic (2.54e-1)" "unprognostic (1.19e-2)" "unprognostic (3.56e-1)" HID1 "C17orf28, DMC1, HID-1" ENSG00000167861 "HID1 domain containing" Q8IV36 17 74950742-74973166 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 146.5;pancreas: 104.3" "Cell type enhanced" "Detected in many" "Enterocytes: 100.7;Goblet cells: 116.1;Mucous neck cells: 59.6;Oligodendrocytes: 65.3;Paneth cells: 61.9;Syncytiotrophoblasts: 60.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 2.6" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "breast cancer: 86.5" "Breast - Breast glandular cells, Breast - Breast glandular cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Somatotropes, Prostate - Prostate glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031406 Approved Supported "Golgi apparatus,Cytosol" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 70: Non-specific - Protein processing" "Cluster 48: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 70: Intestinal goblet cells - Mucin production" 11 "Golgi apparatus, Cytosol" "HPA031406: " "unprognostic (2.34e-3)" "unprognostic (3.19e-3)" "unprognostic (4.78e-2)" "unprognostic (5.22e-2)" "unprognostic (1.71e-2)" "potential prognostic unfavorable (2.05e-4)" "unprognostic (1.29e-1)" "unprognostic (7.87e-3)" "unprognostic (1.23e-1)" "potential prognostic favorable (4.18e-6)" "unprognostic (2.41e-3)" "unprognostic (6.95e-2)" "unprognostic (1.71e-2)" "unprognostic (9.81e-2)" "unprognostic (1.05e-1)" "unprognostic (3.42e-3)" "unprognostic (2.09e-2)" "unprognostic (3.04e-1)" "unprognostic (1.76e-1)" "unprognostic (4.24e-3)" "unprognostic (7.83e-2)" "unprognostic (2.33e-1)" "unprognostic (2.42e-1)" "unprognostic (2.61e-3)" "unprognostic (1.40e-2)" "unprognostic (1.09e-1)" "unprognostic (2.33e-1)" "potential prognostic unfavorable (7.32e-4)" "unprognostic (8.80e-2)" HIF1A "bHLHe78, HIF-1alpha, HIF1, MOP1, PASD8" ENSG00000100644 "Hypoxia inducible factor 1 subunit alpha" Q16665 14 61695513-61748259 "Cancer-related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 423.5" "Cell type enhanced" "Detected in all" "monocytes: 643.4;Neutrophil progenitors: 642.2;Neutrophils: 1937.7;Renal collecting duct principal cells: 611.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 155.1" "Lineage enriched" "Detected in all" 7 "granulocytes: 155.1" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000907, HPA001275, CAB017442" Approved Enhanced "Nucleoplasm,Nuclear bodies" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 44: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 203 "Nucleoplasm, Nuclear bodies" "CAB017442: , HPA000907: , HPA001275: " "unprognostic (2.99e-1)" "unprognostic (1.09e-1)" "unprognostic (4.32e-2)" "unprognostic (2.77e-3)" "unprognostic (9.20e-2)" "unprognostic (2.84e-1)" "unprognostic (4.06e-2)" "unprognostic (5.36e-3)" "unprognostic (1.26e-1)" "unprognostic (3.43e-2)" "unprognostic (2.21e-3)" "unprognostic (2.59e-2)" "unprognostic (2.89e-1)" "unprognostic (5.76e-3)" "unprognostic (2.40e-1)" "unprognostic (4.77e-2)" "unprognostic (1.56e-3)" "unprognostic (3.49e-2)" "unprognostic (1.08e-1)" "unprognostic (4.63e-2)" "potential prognostic unfavorable (1.21e-4)" "unprognostic (2.75e-2)" "unprognostic (6.62e-2)" "unprognostic (1.01e-1)" "unprognostic (9.77e-2)" "unprognostic (1.55e-1)" "unprognostic (3.98e-1)" "unprognostic (1.53e-3)" "unprognostic (2.70e-1)" "unprognostic (5.50e-2)" "unprognostic (6.74e-2)" HIF1AN "DKFZp762F1811, FIH1, FLJ20615, FLJ22027" ENSG00000166135 "Hypoxia inducible factor 1 subunit alpha inhibitor" Q9NWT6 10 100529072-100559998 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 38.9;tongue: 38.1" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 118.8;Late spermatids: 80.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048742, HPA065302, CAB069903" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 118 Nucleoplasm Cytosol "CAB069903: , HPA048742: , HPA065302: " "unprognostic (1.01e-1)" "unprognostic (2.75e-2)" "unprognostic (1.27e-1)" "unprognostic (1.59e-2)" "unprognostic (1.13e-1)" "unprognostic (2.44e-1)" "unprognostic (3.59e-1)" "unprognostic (2.01e-3)" "unprognostic (3.56e-1)" "unprognostic (1.27e-2)" "potential prognostic favorable (2.03e-5)" "unprognostic (5.69e-2)" "unprognostic (1.23e-1)" "unprognostic (7.95e-3)" "unprognostic (2.77e-2)" "unprognostic (4.34e-2)" "unprognostic (2.08e-1)" "unprognostic (2.37e-1)" "unprognostic (1.52e-2)" "validated prognostic unfavorable (2.75e-4)" "validated prognostic unfavorable (6.67e-5)" "unprognostic (6.80e-2)" "unprognostic (4.43e-3)" "unprognostic (5.75e-2)" "unprognostic (3.42e-2)" "unprognostic (1.60e-1)" "unprognostic (8.89e-2)" "unprognostic (1.45e-1)" "unprognostic (1.67e-1)" "unprognostic (6.03e-2)" "unprognostic (4.80e-2)" HIF3A "bHLHe17, IPAS, MOP7, PASD7" ENSG00000124440 "Hypoxia inducible factor 3 subunit alpha" Q9Y2N7 19 46297042-46343433 "Predicted intracellular proteins, Transcription factors" "Angiogenesis, Apoptosis, Stress response, Transcription, Transcription regulation" "Developmental protein, Repressor" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 513.3;Bergmann glia: 491.6;Cardiomyocytes: 251.9;Hematopoietic stem cells: 315.4;Leydig cells: 465.5;Lymphatic endothelial cells: 285.0;Medullary thymic epithelial cells: 242.4;Müller glia: 334.5;Oligodendrocyte progenitor cells: 184.4;Peritubular myoid cells: 346.1;Vascular endothelial cells: 207.8" "Group enriched" "Detected in many" 4 "astrocyte: 545.2;Bergmann glia: 553.0;endothelial cell: 398.9;oligodendrocyte precursor cell: 187.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "testis cancer: 2.1" "Pituitary gland - Somatotropes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041141 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 19: Astrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 3 "Nucleoplasm, Cytosol" "Plasma membrane" "HPA041141: " "unprognostic (2.18e-3)" "unprognostic (1.72e-2)" "unprognostic (1.15e-2)" "unprognostic (2.27e-1)" "unprognostic (3.22e-2)" "unprognostic (3.16e-1)" "unprognostic (2.62e-1)" "unprognostic (1.80e-1)" "unprognostic (1.95e-1)" "unprognostic (1.26e-3)" "unprognostic (5.03e-2)" "unprognostic (8.85e-2)" "unprognostic (1.76e-1)" "unprognostic (5.45e-2)" "unprognostic (2.01e-2)" "unprognostic (1.68e-2)" "unprognostic (4.46e-2)" "unprognostic (2.57e-3)" "unprognostic (1.41e-2)" "unprognostic (1.87e-2)" "unprognostic (8.26e-3)" "unprognostic (6.33e-2)" "unprognostic (3.34e-2)" HIGD1A "DKFZP564K247, HIG1, RCF1A" ENSG00000181061 "HIG1 hypoxia inducible domain family member 1A" Q9Y241 3 42782908-42804490 "Predicted membrane proteins" "Electron transport, Respiratory chain, Stress response, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 15.3;Foveolar cells: 9.7;Gastric chief cells: 13.1;Gastric progenitor cells: 9.0;Hepatic stellate cells: 12.9;Hepatocytes: 37.3;Parietal cells: 63.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 510.4" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043336 Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 27: Non-specific - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 97: Non-specific - Cellular respiration" 5 Mitochondria Nucleoplasm "HPA043336: " "unprognostic (1.13e-2)" "unprognostic (2.58e-1)" "unprognostic (2.02e-1)" "potential prognostic unfavorable (1.11e-4)" "unprognostic (4.56e-3)" "unprognostic (1.27e-1)" "unprognostic (3.36e-2)" "unprognostic (5.22e-2)" "unprognostic (6.81e-2)" "unprognostic (1.92e-3)" "potential prognostic favorable (3.78e-4)" "unprognostic (7.84e-2)" "unprognostic (1.67e-2)" "unprognostic (3.30e-1)" "unprognostic (6.45e-2)" "unprognostic (4.39e-1)" "unprognostic (3.77e-1)" "unprognostic (4.19e-2)" "unprognostic (1.89e-2)" "unprognostic (1.65e-1)" "unprognostic (2.03e-2)" "unprognostic (4.46e-2)" "unprognostic (2.44e-1)" "unprognostic (1.21e-1)" "unprognostic (6.06e-2)" "unprognostic (1.02e-1)" "unprognostic (7.17e-2)" "unprognostic (3.55e-1)" "unprognostic (2.94e-1)" "unprognostic (5.01e-2)" "unprognostic (5.53e-2)" HIGD1B "CLST11240, CLST11240-15" ENSG00000131097 "HIG1 hypoxia inducible domain family member 1B" Q9P298 17 44846353-44850476 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 48.5;placenta: 98.1" "Cell type enriched" "Detected in many" 4 "Pericytes: 340.9" "Group enriched" "Detected in many" 26 "pericyte: 452.8;vascular associated smooth muscle cell: 127.3" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 23.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA079501 Uncertain "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 47: Endothelial cells - Vasculature" "Cluster 27: Breast cancer - Unknown function" "Cluster 110: Mural cells - ECM organization" "Microtubules, Cytokinetic bridge, Mitotic spindle" "HPA079501: " "unprognostic (9.31e-2)" "unprognostic (3.85e-2)" "unprognostic (1.88e-1)" "unprognostic (3.74e-2)" "unprognostic (4.34e-2)" "unprognostic (1.26e-1)" "unprognostic (8.32e-2)" "unprognostic (4.57e-2)" "unprognostic (1.04e-2)" "unprognostic (4.74e-2)" "unprognostic (1.83e-2)" "potential prognostic favorable (2.72e-4)" "unprognostic (6.53e-3)" "unprognostic (1.52e-2)" "unprognostic (1.51e-1)" "unprognostic (3.03e-2)" "unprognostic (1.22e-2)" "potential prognostic unfavorable (9.17e-4)" "unprognostic (4.96e-2)" "unprognostic (2.12e-1)" "unprognostic (3.79e-3)" "unprognostic (1.18e-1)" "unprognostic (1.39e-1)" "unprognostic (4.69e-2)" "potential prognostic unfavorable (7.95e-4)" "unprognostic (2.41e-3)" "potential prognostic unfavorable (9.27e-5)" "unprognostic (3.96e-1)" "unprognostic (3.17e-2)" "unprognostic (1.46e-1)" HIGD1C Gm921 ENSG00000214511 "HIG1 hypoxia inducible domain family member 1C" A8MV81 12 50952538-50970607 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Astrocytes: 4.0;Bergmann glia: 6.1;Brain excitatory neurons: 3.8;Brain inhibitory neurons: 3.1;Distal convoluted tubule cells: 2.1;Ependymal cells: 2.8;Loop of henle epithelial cells: 3.3;Microglia: 7.2;Oligodendrocyte progenitor cells: 6.0;Oligodendrocytes: 4.9;Other brain neurons: 3.5;Papillary tip epithelial cells: 3.8;Proximal tubule cells: 2.2;Renal collecting duct principal cells: 3.6;Renal connecting tubule cells: 3.3" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Region enriched" "Detected in single" 10 "hypothalamus: 1.0" "Low region specificity" "Detected in all" NA NA "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 98: Neurons - Neurotransmission & signaling" 11 "unprognostic (2.84e-2)" "unprognostic (7.26e-2)" "unprognostic (1.83e-1)" HIGD2A "MGC2198, RCF1B" ENSG00000146066 "HIG1 hypoxia inducible domain family member 2A" Q9BW72 5 176388751-176389761 "Essential proteins, Metabolic proteins, Predicted membrane proteins, Transporters" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial secretory cells: 32.7;Gastric chief cells: 57.9;Mucous neck cells: 44.4;Parietal cells: 104.3;Suprabasal keratinocytes: 33.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" HPA042715 Uncertain Supported Mitochondria,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 52: Non-specific - Cellular respiration" "Cluster 39: Astrocytes - Mixed function" "Cluster 25: Non-specific - Ribosome" "Cluster 97: Non-specific - Cellular respiration" 1 Mitochondria Cytosol "HPA042715: " "unprognostic (6.52e-2)" "unprognostic (2.76e-1)" "unprognostic (2.70e-1)" "unprognostic (3.36e-3)" "unprognostic (7.15e-2)" "unprognostic (2.33e-1)" "unprognostic (1.75e-1)" "unprognostic (4.98e-1)" "unprognostic (3.05e-1)" "unprognostic (8.57e-3)" "unprognostic (8.56e-2)" "unprognostic (4.97e-2)" "unprognostic (3.75e-1)" "unprognostic (1.82e-3)" "unprognostic (1.89e-3)" "unprognostic (1.96e-2)" "unprognostic (3.22e-1)" "unprognostic (3.34e-1)" "unprognostic (8.66e-2)" "unprognostic (2.65e-2)" "unprognostic (6.24e-2)" "unprognostic (1.29e-3)" "unprognostic (1.14e-1)" "unprognostic (3.50e-1)" "unprognostic (2.01e-2)" "unprognostic (1.24e-1)" "unprognostic (1.51e-1)" "unprognostic (1.46e-1)" "unprognostic (1.03e-1)" "unprognostic (1.79e-1)" "unprognostic (2.14e-1)" HIGD2B HIGD2BP ENSG00000175202 "HIG1 hypoxia inducible domain family member 2B" Q4VC39 15 72675798-72686182 "Essential proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 10 "testis: 3.4" "Group enriched" "Detected in some" 12 "Early primary spermatocytes: 10.7;Early spermatids: 13.5;Late primary spermatocytes: 41.4;Late spermatids: 12.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "HPA019016, HPA042715" Uncertain Supported Mitochondria,Cytosol NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 2 Mitochondria Cytosol "HPA019016: , HPA042715: " HIKESHI "C11orf73, HSPC138, HSPC179, OPI10" ENSG00000149196 "Heat shock protein nuclear import factor hikeshi" Q53FT3 11 86302211-86345943 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012708, HPA035063, HPA035064" Approved Approved "Nucleoplasm,Nuclear speckles,Nuclear bodies" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" "Nuclear speckles" "Nucleoplasm, Nuclear bodies" "HPA012708: , HPA035063: , HPA035064: " "unprognostic (1.79e-3)" "unprognostic (5.59e-3)" "unprognostic (9.70e-2)" "unprognostic (8.75e-2)" "unprognostic (1.56e-1)" "unprognostic (8.97e-2)" "unprognostic (3.05e-3)" "unprognostic (1.61e-1)" "unprognostic (1.24e-1)" "unprognostic (1.33e-3)" "potential prognostic unfavorable (3.34e-4)" "unprognostic (1.27e-2)" "potential prognostic unfavorable (1.31e-4)" "unprognostic (3.11e-2)" "unprognostic (1.14e-2)" "unprognostic (8.90e-2)" "unprognostic (3.58e-1)" "unprognostic (1.26e-2)" "unprognostic (1.58e-1)" "unprognostic (8.85e-3)" "unprognostic (5.05e-3)" "unprognostic (8.35e-2)" "unprognostic (8.73e-3)" "unprognostic (1.94e-2)" "unprognostic (1.13e-1)" "unprognostic (2.92e-3)" "unprognostic (2.65e-1)" "potential prognostic favorable (9.95e-4)" "unprognostic (1.45e-1)" HILPDA "C7orf68, FLJ21076, HIG-2, HIG2" ENSG00000135245 "Hypoxia inducible lipid droplet associated" Q9Y5L2 7 128455849-128458418 "Predicted intracellular proteins" "Stress response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 158.6" "Cell type enhanced" "Detected in some" "Astrocytes: 29.6;Bergmann glia: 8.7;Brain excitatory neurons: 4.0;Brain inhibitory neurons: 3.6;Ependymal cells: 4.7;Esophageal apical cells: 6.2;Microglia: 3.6;Oligodendrocyte progenitor cells: 4.4;Oligodendrocytes: 4.5;Other brain neurons: 4.2;Papillary tip epithelial cells: 10.6;Podocytes: 8.3;Proximal tubule cells: 4.0" "Cell type enhanced" "Detected in all" "astrocyte: 60.7;endothelial cell: 59.6" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 271.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 67.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010515 Approved Supported "Nucleoplasm,Lipid droplets" "Intracellular and membrane" Other NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 44: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 104: Brain endothelial cells - Blood brain barrier" 1 "Lipid droplets" Nucleoplasm "HPA010515: " "unprognostic (4.14e-1)" "unprognostic (1.83e-3)" "unprognostic (1.41e-3)" "unprognostic (6.72e-2)" "unprognostic (3.61e-1)" "unprognostic (1.15e-2)" "unprognostic (1.26e-2)" "unprognostic (3.45e-2)" "potential prognostic unfavorable (8.88e-7)" "unprognostic (3.36e-3)" "unprognostic (2.67e-2)" "unprognostic (4.23e-2)" "potential prognostic unfavorable (5.46e-12)" "unprognostic (4.50e-3)" "potential prognostic unfavorable (8.29e-5)" "unprognostic (1.68e-1)" "unprognostic (2.38e-1)" "unprognostic (3.90e-2)" "unprognostic (3.35e-1)" "unprognostic (2.67e-3)" "unprognostic (9.94e-3)" "potential prognostic unfavorable (1.30e-4)" "unprognostic (1.03e-1)" "unprognostic (2.63e-2)" "unprognostic (5.58e-3)" "unprognostic (7.53e-3)" "unprognostic (9.54e-2)" "unprognostic (2.72e-2)" "unprognostic (7.25e-2)" HINFP "DKFZP434F162, HiNF-P, MIZF, ZNF743" ENSG00000172273 "Histone H4 transcription factor" Q9BQA5 11 119121580-119136059 "Essential proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 69.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061008 Uncertain NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 64: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 10 "HPA061008: " "unprognostic (2.75e-1)" "unprognostic (2.23e-2)" "unprognostic (3.01e-1)" "unprognostic (8.23e-2)" "unprognostic (1.71e-1)" "unprognostic (3.55e-1)" "unprognostic (1.23e-1)" "potential prognostic favorable (4.56e-5)" "unprognostic (6.17e-2)" "unprognostic (3.62e-3)" "unprognostic (3.55e-3)" "unprognostic (1.38e-3)" "unprognostic (3.53e-3)" "unprognostic (1.08e-3)" "unprognostic (1.58e-1)" "unprognostic (2.29e-1)" "unprognostic (4.63e-3)" "unprognostic (2.96e-1)" "unprognostic (7.91e-2)" "unprognostic (3.87e-1)" "unprognostic (2.10e-1)" "unprognostic (1.85e-1)" "unprognostic (2.19e-2)" "unprognostic (8.77e-3)" "potential prognostic favorable (3.26e-4)" "unprognostic (3.99e-2)" "unprognostic (1.17e-2)" "unprognostic (3.71e-2)" "unprognostic (1.62e-1)" "unprognostic (5.38e-2)" "unprognostic (1.46e-1)" HINT1 "HINT, PKCI-1, PRKCNH1" ENSG00000169567 "Histidine triad nucleotide binding protein 1" P49773 5 131155383-131224468 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 2165.4;Extravillous trophoblasts: 2146.9;Hepatocytes: 2646.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044577 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 1500000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 76: Non-specific - Metabolism" "Cluster 27: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 97: Non-specific - Cellular respiration" 18 "Plasma membrane, Cytosol" Nucleoplasm "HPA044577: " "unprognostic (1.49e-1)" "unprognostic (8.15e-2)" "unprognostic (1.85e-1)" "unprognostic (4.00e-3)" "unprognostic (3.41e-3)" "unprognostic (1.64e-2)" "unprognostic (5.66e-3)" "unprognostic (2.66e-1)" "unprognostic (1.00e-2)" "potential prognostic unfavorable (1.47e-4)" "unprognostic (2.48e-3)" "unprognostic (2.44e-1)" "unprognostic (3.65e-1)" "potential prognostic unfavorable (4.42e-4)" "unprognostic (5.23e-2)" "unprognostic (2.11e-2)" "unprognostic (6.67e-2)" "unprognostic (1.54e-1)" "unprognostic (7.93e-2)" "unprognostic (3.11e-1)" "unprognostic (6.86e-2)" "unprognostic (3.68e-1)" "unprognostic (6.59e-3)" "unprognostic (3.97e-1)" "unprognostic (1.28e-2)" "unprognostic (5.91e-3)" "unprognostic (3.50e-3)" "unprognostic (1.54e-1)" "unprognostic (1.41e-1)" "unprognostic (1.80e-1)" "unprognostic (1.86e-2)" HINT2 ENSG00000137133 "Histidine triad nucleotide binding protein 2" Q9BX68 9 35812960-35815354 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric chief cells: 21.8;Hepatocytes: 24.4;Megakaryocytes: 24.7;Parietal cells: 37.1" "Cell type enhanced" "Detected in single" "pericyte: 1.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "HPA020961, HPA059109" Supported Enhanced Mitochondria NA NA 100000 "Cluster 13: Non-specific - Mitochondria" "Cluster 76: Non-specific - Metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 25 Mitochondria "HPA020961: , HPA059109: " "unprognostic (6.14e-2)" "unprognostic (6.57e-3)" "unprognostic (1.34e-1)" "unprognostic (4.10e-3)" "unprognostic (1.61e-1)" "unprognostic (3.25e-2)" "unprognostic (2.42e-1)" "unprognostic (9.86e-2)" "unprognostic (1.17e-1)" "unprognostic (5.81e-2)" "potential prognostic favorable (2.53e-6)" "unprognostic (1.66e-2)" "potential prognostic favorable (4.07e-8)" "unprognostic (3.20e-2)" "unprognostic (5.90e-2)" "unprognostic (2.15e-1)" "unprognostic (3.34e-2)" "unprognostic (2.88e-1)" "unprognostic (4.16e-2)" "unprognostic (8.73e-3)" "unprognostic (7.33e-3)" "unprognostic (1.08e-2)" "unprognostic (8.49e-2)" "unprognostic (4.53e-2)" "unprognostic (1.07e-1)" "unprognostic (7.95e-2)" "unprognostic (1.92e-2)" "unprognostic (1.34e-1)" "unprognostic (5.97e-2)" "unprognostic (1.59e-1)" "unprognostic (1.84e-1)" HINT3 "FLJ33126, HINT4" ENSG00000111911 "Histidine triad nucleotide binding protein 3" Q9NQE9 6 125956770-125980244 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 105.5" "Cell type enhanced" "Detected in all" "Early spermatids: 395.5;Late primary spermatocytes: 260.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027914 Approved Approved Nucleoli,Mitochondria,Cytosol NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Ribosome" "Cluster 28: Non-specific - Nuclear processes" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 4 "Nucleoli, Mitochondria" Cytosol "HPA027914: " "unprognostic (6.26e-2)" "potential prognostic unfavorable (8.74e-4)" "unprognostic (1.58e-1)" "unprognostic (1.45e-2)" "unprognostic (1.27e-1)" "unprognostic (9.18e-2)" "unprognostic (6.76e-2)" "unprognostic (1.55e-1)" "unprognostic (4.33e-1)" "unprognostic (1.54e-1)" "potential prognostic favorable (1.18e-7)" "unprognostic (5.53e-3)" "unprognostic (1.44e-1)" "unprognostic (9.87e-2)" "unprognostic (1.25e-1)" "unprognostic (9.39e-3)" "unprognostic (1.04e-1)" "unprognostic (4.61e-2)" "unprognostic (2.84e-1)" "unprognostic (7.41e-2)" "potential prognostic unfavorable (5.62e-7)" "unprognostic (2.38e-1)" "unprognostic (2.43e-1)" "unprognostic (3.59e-2)" "unprognostic (7.51e-3)" "unprognostic (4.95e-1)" "unprognostic (2.08e-1)" "unprognostic (1.21e-1)" "unprognostic (1.50e-1)" "unprognostic (1.02e-1)" "unprognostic (1.22e-1)" HIP1 ILWEQ ENSG00000127946 "Huntingtin interacting protein 1" O00291 7 75533298-75738962 "Cancer-related genes, Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Apoptosis, Differentiation, Endocytosis, Transcription, Transcription regulation" "Actin-binding, Activator" "Cancer-related genes, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 532.2;Late spermatids: 2445.9;Loop of henle epithelial cells: 870.4;Oligodendrocyte progenitor cells: 545.9;Oligodendrocytes: 516.1;Renal collecting duct principal cells: 537.3;Vascular smooth muscle cells: 512.0" "Cell type enhanced" "Detected in all" "oligodendrocyte: 575.9;oligodendrocyte precursor cell: 682.4;vascular associated smooth muscle cell: 744.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 9.6;eosinophil: 6.9;neutrophil: 6.8;NK-cell: 3.0;plasmacytoid DC: 3.3" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Stomach - Endothelial cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013606, CAB015334, CAB016402, HPA017964" Enhanced Supported "Vesicles,Acrosome,Mid piece,Principal piece" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 11: White matter - Signal transduction" "Cluster 39: Non-specific - Transcription" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 70 Vesicles "Acrosome, Mid piece, Principal piece" "CAB015334: , CAB016402: , HPA013606: , HPA017964: " "unprognostic (2.40e-3)" "unprognostic (1.50e-2)" "unprognostic (1.49e-2)" "unprognostic (4.97e-2)" "unprognostic (2.43e-2)" "unprognostic (2.99e-2)" "unprognostic (3.94e-1)" "unprognostic (2.04e-1)" "unprognostic (1.24e-1)" "unprognostic (1.07e-1)" "validated prognostic favorable (4.60e-4)" "validated prognostic favorable (6.80e-4)" "unprognostic (1.40e-1)" "unprognostic (1.37e-2)" "unprognostic (2.91e-1)" "unprognostic (2.84e-2)" "unprognostic (2.97e-1)" "unprognostic (2.05e-1)" "unprognostic (1.26e-1)" "unprognostic (3.13e-3)" "unprognostic (4.39e-1)" "unprognostic (1.30e-2)" "unprognostic (2.56e-1)" "unprognostic (1.45e-1)" "unprognostic (6.69e-2)" "unprognostic (7.24e-2)" "unprognostic (7.90e-2)" "unprognostic (1.63e-1)" "unprognostic (1.86e-1)" "unprognostic (5.41e-2)" "unprognostic (3.06e-2)" HIP1R "FLJ14000, HIP12, HIP3, ILWEQ, KIAA0655" ENSG00000130787 "Huntingtin interacting protein 1 related" O75146 12 122834453-122862961 "Cancer-related genes, Predicted intracellular proteins" Endocytosis Actin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte progenitor cells: 255.7;Renal collecting duct principal cells: 125.1;Renal connecting tubule cells: 127.8;Somatotrophs: 168.4;Thyrotrophs: 159.0;Tuft cells: 311.3" "Cell type enhanced" "Detected in all" "oligodendrocyte precursor cell: 303.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 9.3;naive B-cell: 10.6" "Group enriched" "Detected in many" 8 "B-cells: 10.6;granulocytes: 2.9;T-cells: 3.0" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Prostate - Prostate basal glandular cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017187, HPA038135, HPA038136" Enhanced Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 33 "Plasma membrane, Cytosol" Vesicles "CAB017187: , HPA038135: , HPA038136: " "unprognostic (3.64e-2)" "unprognostic (9.90e-2)" "unprognostic (6.35e-2)" "unprognostic (2.80e-2)" "unprognostic (1.53e-1)" "unprognostic (1.58e-3)" "unprognostic (1.10e-1)" "unprognostic (4.80e-2)" "unprognostic (1.08e-2)" "unprognostic (1.07e-1)" "validated prognostic favorable (8.67e-6)" "validated prognostic favorable (9.52e-4)" "unprognostic (2.59e-3)" "unprognostic (1.82e-2)" "unprognostic (1.10e-1)" "unprognostic (1.10e-1)" "unprognostic (1.85e-1)" "unprognostic (5.20e-1)" "unprognostic (8.42e-2)" "unprognostic (4.88e-1)" "unprognostic (1.41e-1)" "unprognostic (7.65e-3)" "unprognostic (1.99e-1)" "unprognostic (1.08e-1)" "unprognostic (3.63e-1)" "unprognostic (1.04e-1)" "unprognostic (1.32e-2)" "unprognostic (8.38e-2)" "unprognostic (4.64e-1)" "unprognostic (3.00e-2)" "unprognostic (2.46e-1)" HIPK1 "KIAA0630, MGC26642, MGC33446, MGC33548, Myak, Nbak2" ENSG00000163349 "Homeodomain interacting protein kinase 1" Q86Z02 1 113929324-113977869 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 134.1" "Cell type enhanced" "Detected in many" "Fallopian tube ciliated cells: 293.5;Neutrophil progenitors: 548.7;Neutrophils: 470.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016664 Approved Supported "Nucleoplasm,Centrosome,Basal body,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 44: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 8 "Nucleoplasm, Basal body, Cytosol" Centrosome "HPA016664: " "unprognostic (4.75e-2)" "unprognostic (3.63e-1)" "unprognostic (6.23e-2)" "unprognostic (2.24e-1)" "unprognostic (1.61e-2)" "unprognostic (1.92e-1)" "unprognostic (4.96e-2)" "unprognostic (1.37e-1)" "unprognostic (1.88e-2)" "unprognostic (4.98e-2)" "validated prognostic favorable (1.99e-4)" "validated prognostic favorable (3.55e-4)" "unprognostic (6.22e-2)" "potential prognostic unfavorable (8.47e-4)" "unprognostic (1.49e-1)" "unprognostic (1.45e-1)" "unprognostic (2.32e-3)" "unprognostic (6.43e-2)" "unprognostic (1.62e-1)" "unprognostic (3.09e-2)" "unprognostic (1.31e-1)" "unprognostic (2.31e-2)" "unprognostic (2.40e-1)" "unprognostic (7.30e-2)" "unprognostic (2.55e-2)" "unprognostic (2.18e-1)" "unprognostic (7.00e-2)" "unprognostic (2.90e-1)" "unprognostic (2.44e-1)" "unprognostic (5.77e-2)" "unprognostic (1.87e-1)" HIPK2 ENSG00000064393 "Homeodomain interacting protein kinase 2" Q9H2X6 7 139561570-139777998 "Enzymes, Plasma proteins, Predicted membrane proteins" "Apoptosis, DNA damage, Host-virus interaction, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "brain: 146.1" "Cell type enhanced" "Detected in all" "Plasma cells: 825.1;Somatotrophs: 854.2" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 750.3;oligodendrocyte: 747.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "basophil: 27.5" "Lineage enriched" "Detected in many" 7 "granulocytes: 27.5" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Adrenal cortex cells, Colon - Endothelial cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007611 Supported Supported Nucleoplasm NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 44: Plasma cells - Antibody production & secretion" 52 Nucleoplasm "HPA007611: " "unprognostic (3.55e-2)" "unprognostic (1.46e-2)" "unprognostic (2.19e-2)" "unprognostic (2.17e-3)" "unprognostic (4.80e-2)" "unprognostic (1.41e-1)" "unprognostic (6.61e-2)" "unprognostic (4.69e-3)" "unprognostic (2.04e-1)" "unprognostic (3.98e-2)" "potential prognostic favorable (2.48e-9)" "unprognostic (2.13e-2)" "unprognostic (2.15e-1)" "unprognostic (2.97e-1)" "unprognostic (2.19e-2)" "unprognostic (2.36e-1)" "unprognostic (8.49e-2)" "unprognostic (3.89e-3)" "unprognostic (5.69e-1)" "unprognostic (2.64e-1)" "unprognostic (4.55e-1)" "unprognostic (1.66e-3)" "unprognostic (1.92e-3)" "unprognostic (1.45e-1)" "unprognostic (3.30e-1)" "unprognostic (9.09e-2)" "unprognostic (7.30e-2)" "unprognostic (4.85e-1)" "unprognostic (3.82e-2)" "unprognostic (6.13e-2)" "unprognostic (4.32e-2)" HIPK3 "DYRK6, FIST3, PKY, YAK1" ENSG00000110422 "Homeodomain interacting protein kinase 3" Q9H422 11 33256672-33357023 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 1249.2" "Cell type enhanced" "Detected in all" "ependymal cell: 503.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028069 Approved Supported "Nuclear bodies,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 39: Astrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" 1 Cytosol "Nuclear bodies" "HPA028069: " "unprognostic (6.91e-2)" "unprognostic (1.15e-1)" "unprognostic (7.65e-2)" "unprognostic (2.16e-3)" "unprognostic (8.79e-2)" "unprognostic (9.70e-2)" "unprognostic (2.47e-1)" "unprognostic (1.27e-1)" "unprognostic (1.44e-2)" "potential prognostic unfavorable (9.17e-5)" "validated prognostic favorable (9.25e-7)" "validated prognostic favorable (7.21e-5)" "unprognostic (9.67e-2)" "unprognostic (8.05e-2)" "unprognostic (4.18e-2)" "unprognostic (2.54e-1)" "unprognostic (4.00e-1)" "unprognostic (4.27e-1)" "unprognostic (1.88e-1)" "unprognostic (2.58e-1)" "unprognostic (2.31e-3)" "unprognostic (3.01e-1)" "unprognostic (2.50e-2)" "unprognostic (1.39e-1)" "unprognostic (1.26e-1)" "unprognostic (1.04e-1)" "unprognostic (2.26e-1)" "unprognostic (8.15e-3)" "unprognostic (2.96e-1)" "unprognostic (1.72e-1)" "potential prognostic unfavorable (9.54e-5)" HIPK4 FLJ32818 ENSG00000160396 "Homeodomain interacting protein kinase 4" Q8NE63 19 40379271-40390181 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "brain: 9.0;testis: 17.2" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 40.5;Early spermatids: 78.1;Epididymal basal cells: 36.2;Late primary spermatocytes: 96.4;Late spermatids: 39.5;Myonuclei: 26.5;Oocytes: 64.5;Retinal ganglion cells: 27.0" "Cell type enhanced" "Detected in many" "hippocampal dentate gyrus: 34.3;medium spiny neuron: 35.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 67: Testis - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" 3 "unprognostic (1.11e-1)" HIRA "DGCR1, TUP1, TUPLE1" ENSG00000100084 "Histone cell cycle regulator" P54198 22 19330698-19447450 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB039243, CAB039244, HPA050714, HPA052902" Enhanced Enhanced Nucleoplasm NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 33: Thyroid gland - Tissue development" "Cluster 38: Sub-cortical - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 40 Nucleoplasm "CAB039243: , CAB039244: , HPA050714: , HPA052902: " "unprognostic (3.24e-1)" "unprognostic (1.67e-3)" "unprognostic (3.47e-1)" "unprognostic (2.52e-1)" "unprognostic (8.41e-3)" "unprognostic (5.04e-2)" "unprognostic (6.77e-2)" "potential prognostic favorable (9.86e-4)" "unprognostic (3.04e-1)" "unprognostic (1.45e-1)" "potential prognostic favorable (2.54e-7)" "unprognostic (1.96e-3)" "potential prognostic favorable (6.90e-4)" "unprognostic (4.97e-2)" "unprognostic (3.08e-1)" "unprognostic (1.63e-1)" "unprognostic (5.56e-2)" "unprognostic (3.90e-2)" "unprognostic (8.31e-3)" "unprognostic (1.93e-1)" "unprognostic (5.23e-2)" "unprognostic (1.85e-2)" "unprognostic (8.32e-2)" "unprognostic (2.99e-1)" "unprognostic (1.47e-3)" "unprognostic (2.95e-2)" "unprognostic (6.94e-2)" "unprognostic (1.18e-1)" "unprognostic (2.42e-1)" "unprognostic (2.85e-1)" "unprognostic (5.45e-2)" HIRIP3 ENSG00000149929 "HIRA interacting protein 3" Q9BW71 16 29992330-29996074 "Metabolic proteins, Predicted intracellular proteins" "Chaperone, Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 84.8;Late primary spermatocytes: 160.9;Megakaryocyte progenitors: 66.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051897, HPA063205" Approved Supported Nucleoplasm,Nucleoli No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 27: Non-specific - Cell proliferation" 19 Nucleoplasm Nucleoli "HPA051897: , HPA063205: " "unprognostic (4.62e-2)" "unprognostic (2.60e-2)" "unprognostic (1.58e-1)" "unprognostic (2.44e-1)" "unprognostic (4.14e-3)" "unprognostic (1.26e-1)" "unprognostic (2.15e-2)" "potential prognostic favorable (4.18e-4)" "unprognostic (1.31e-1)" "unprognostic (5.62e-2)" "potential prognostic favorable (1.58e-5)" "unprognostic (3.10e-2)" "unprognostic (1.76e-3)" "unprognostic (6.39e-2)" "unprognostic (5.66e-2)" "unprognostic (1.99e-1)" "unprognostic (3.13e-2)" "unprognostic (2.19e-2)" "unprognostic (1.24e-1)" "unprognostic (1.49e-1)" "unprognostic (8.33e-2)" "unprognostic (6.74e-2)" "unprognostic (1.61e-2)" "unprognostic (9.61e-2)" "unprognostic (5.19e-2)" "unprognostic (1.25e-1)" "unprognostic (6.95e-2)" "unprognostic (5.50e-2)" "unprognostic (1.71e-1)" "unprognostic (1.64e-1)" "unprognostic (1.17e-1)" HIVEP1 "CIRIP, CRYBP1, MBP-1, PRDII-BF1, Schnurri-1, ZAS1, ZNF40, ZNF40A" ENSG00000095951 "HIVEP zinc finger 1" P15822 6 12008762-12164999 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 713.8;pDCs: 481.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050724, HPA067457" Approved Supported "Nucleoplasm,Nuclear bodies,Mitochondria,Cytosol" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 37 Nucleoplasm "Nuclear bodies, Mitochondria, Cytosol" "HPA050724: , HPA067457: " "unprognostic (1.85e-1)" "unprognostic (1.74e-1)" "unprognostic (3.12e-1)" "unprognostic (2.36e-2)" "unprognostic (1.53e-1)" "unprognostic (8.02e-2)" "unprognostic (5.76e-2)" "unprognostic (2.57e-2)" "unprognostic (1.71e-2)" "unprognostic (2.57e-3)" "potential prognostic favorable (2.13e-4)" "unprognostic (4.76e-3)" "unprognostic (1.14e-1)" "unprognostic (4.53e-2)" "unprognostic (1.74e-1)" "unprognostic (2.08e-1)" "unprognostic (1.42e-1)" "unprognostic (1.50e-1)" "unprognostic (5.79e-2)" "unprognostic (2.23e-1)" "unprognostic (2.56e-2)" "unprognostic (3.83e-2)" "unprognostic (7.22e-2)" "unprognostic (3.62e-1)" "unprognostic (3.09e-3)" "unprognostic (3.77e-2)" "unprognostic (3.10e-1)" "unprognostic (5.63e-2)" "unprognostic (3.29e-1)" "unprognostic (1.21e-1)" "unprognostic (6.20e-2)" HIVEP2 "HIV-EP2, MBP-2, MIBP1, Schnurri-2, ZAS2, ZNF40B" ENSG00000010818 "HIVEP zinc finger 2" P31629 6 142751469-142956698 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial glandular cells: 1348.5;Salivary basal cells: 708.2;Urothelial cells: 842.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055954 Supported Nucleoplasm NA NA "Cluster 11: T-cells - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 6: Leukemia - Signal transduction" "Cluster 51: Secretory epithelial cells - Mixed function" 7 Nucleoplasm "HPA055954: " "unprognostic (6.73e-2)" "unprognostic (2.79e-2)" "unprognostic (2.63e-1)" "potential prognostic unfavorable (1.90e-4)" "unprognostic (4.01e-1)" "potential prognostic unfavorable (3.59e-4)" "unprognostic (1.58e-1)" "unprognostic (2.34e-2)" "unprognostic (1.74e-2)" "unprognostic (6.39e-2)" "validated prognostic favorable (3.80e-5)" "validated prognostic favorable (1.59e-4)" "unprognostic (1.05e-1)" "unprognostic (5.67e-2)" "unprognostic (3.72e-2)" "unprognostic (7.37e-2)" "potential prognostic unfavorable (7.25e-4)" "unprognostic (1.69e-1)" "unprognostic (1.41e-1)" "unprognostic (1.52e-3)" "unprognostic (2.17e-1)" "unprognostic (3.58e-2)" "unprognostic (5.45e-3)" "unprognostic (1.47e-1)" "unprognostic (4.28e-2)" "unprognostic (7.18e-3)" "unprognostic (1.23e-1)" "unprognostic (1.95e-2)" "unprognostic (8.15e-2)" "unprognostic (1.72e-1)" "unprognostic (9.17e-2)" HIVEP3 "FLJ16752, KBP-1, KBP1, KIAA1555, KRC, Schnurri-3, SHN3, ZAS3, ZNF40C" ENSG00000127124 "HIVEP zinc finger 3" Q5T1R4 1 41506365-42035925 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 6.2" "Cell type enhanced" "Detected in many" "Corticotrophs: 516.2;Lactotrophs: 519.5;Microglia: 481.2;Retinal amacrine cells: 559.7;Retinal horizontal cells: 544.9;Thymocytes: 462.4;Thyrotrophs: 595.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Testis - Spermatogonia" "Low region specificity" "Detected in all" HPA005728 Approved Approved Nucleoplasm NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 2: Non-specific - Mixed function" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 55: Lymphoma - Immune response" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 6 Nucleoplasm "HPA005728: " "unprognostic (2.31e-1)" "unprognostic (4.42e-2)" "unprognostic (1.75e-1)" "unprognostic (2.37e-1)" "unprognostic (1.15e-1)" "unprognostic (6.43e-2)" "unprognostic (1.17e-1)" "unprognostic (5.25e-2)" "unprognostic (7.64e-2)" "unprognostic (2.38e-1)" "unprognostic (1.34e-1)" "unprognostic (1.90e-1)" "unprognostic (2.89e-2)" "unprognostic (3.24e-1)" "unprognostic (1.89e-1)" "unprognostic (1.14e-1)" "unprognostic (1.16e-1)" "unprognostic (7.88e-3)" "unprognostic (2.05e-1)" "unprognostic (6.85e-2)" "unprognostic (1.21e-1)" "unprognostic (2.41e-1)" "unprognostic (4.93e-3)" HJURP "DKFZp762E1312, FAKTS, hFLEG1, URLC9" ENSG00000123485 "Holliday junction recognition protein" Q8NCD3 2 233833416-233854566 "Essential proteins, Predicted intracellular proteins" "Cell cycle" "Chaperone, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 44.7;lymphoid tissue: 28.3" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 27.2;Early spermatids: 17.5;Enteric transient amplifying cells: 22.5;Erythrocyte progenitors: 53.1;Extravillous trophoblasts: 18.4;Gastric progenitor cells: 20.5;Late primary spermatocytes: 58.7;Megakaryocyte progenitors: 36.2;Monocyte progenitors: 65.5;Neutrophil progenitors: 24.7;Oocytes: 96.7" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.2" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008436, HPA027261" Uncertain Approved Nucleoplasm,Nucleoli,Cytosol Yes Yes "Cluster 9: T-regs - Cell cycle regulation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 48: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Non-specific - Cell proliferation" 24 "Nucleoplasm, Nucleoli" Cytosol "HPA008436: , HPA027261: " "unprognostic (5.36e-2)" "unprognostic (8.88e-2)" "unprognostic (6.18e-2)" "unprognostic (1.46e-1)" "unprognostic (2.39e-1)" "unprognostic (3.80e-1)" "unprognostic (5.10e-1)" "unprognostic (7.09e-2)" "unprognostic (5.08e-2)" "validated prognostic unfavorable (2.25e-12)" "validated prognostic unfavorable (9.81e-6)" "potential prognostic unfavorable (1.30e-9)" "validated prognostic unfavorable (1.96e-6)" "validated prognostic unfavorable (1.14e-9)" "potential prognostic unfavorable (3.55e-6)" "unprognostic (5.15e-3)" "unprognostic (2.01e-2)" "unprognostic (2.05e-2)" "unprognostic (5.27e-2)" "unprognostic (5.70e-2)" "potential prognostic unfavorable (1.07e-5)" "unprognostic (3.57e-3)" "unprognostic (3.61e-2)" "unprognostic (7.77e-2)" "unprognostic (1.53e-1)" "potential prognostic unfavorable (4.64e-4)" "unprognostic (5.06e-2)" "unprognostic (1.62e-1)" "unprognostic (6.50e-2)" HJV "haemojuvelin, hemojuvelin, HFE2, HFE2A, JH, RGMC" ENSG00000168509 "Hemojuvelin BMP co-receptor" Q6ZVN8 1 146017468-146036746 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "liver: 223.7;skeletal muscle: 553.9;tongue: 271.9" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 192.1" "Low cell type specificity" "Detected in some" "Cancer enriched" "Detected in some" 81 "Liver Hepatocellular Carcinoma (TCGA): 160.2" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Sarcoma: 1.1" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA 67000 "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 2 "unprognostic (3.64e-2)" "unprognostic (5.01e-3)" HK1 ENSG00000156515 "Hexokinase 1" P19367 10 69269984-69401884 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycolysis, Immunity, Inflammatory response, Innate immunity" "Allosteric enzyme, Kinase, Transferase" "Cancer-related genes, Charcot-Marie-Tooth disease, Disease variant, Hereditary hemolytic anemia, Intellectual disability, Neurodegeneration, Neuropathy, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 441.9;Late spermatids: 1797.7;Retinal horizontal cells: 717.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007043, HPA007044, CAB010052" Supported Enhanced Mitochondria NA NA 2400000 "Cluster 40: Monocytes - Innate immune response" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 1: Neurons - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 18 Mitochondria "CAB010052: , HPA007043: , HPA007044: " "unprognostic (1.25e-1)" "unprognostic (2.82e-2)" "unprognostic (1.75e-1)" "unprognostic (7.96e-2)" "unprognostic (6.06e-2)" "unprognostic (5.84e-2)" "unprognostic (3.79e-3)" "unprognostic (3.39e-1)" "potential prognostic unfavorable (3.19e-6)" "unprognostic (4.25e-2)" "unprognostic (1.54e-3)" "unprognostic (7.94e-2)" "unprognostic (2.02e-1)" "unprognostic (3.68e-2)" "unprognostic (7.19e-2)" "unprognostic (4.19e-2)" "potential prognostic unfavorable (6.43e-4)" "unprognostic (1.11e-1)" "unprognostic (3.04e-3)" "unprognostic (8.35e-3)" "unprognostic (7.44e-2)" "unprognostic (1.59e-3)" "unprognostic (5.41e-2)" "unprognostic (6.31e-2)" "unprognostic (4.14e-2)" "unprognostic (2.18e-1)" "unprognostic (5.57e-2)" "unprognostic (1.08e-1)" "unprognostic (1.31e-2)" "unprognostic (4.73e-3)" "unprognostic (7.04e-2)" HK2 ENSG00000159399 "Hexokinase 2" P52789 2 74834127-74893359 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 133.5" "Cell type enhanced" "Detected in many" "Adipocytes: 305.2;Colonocytes: 164.0;Cone photoreceptor cells: 196.7;Esophageal apical cells: 285.6;Neutrophils: 163.4;Urothelial cells: 171.1" "Group enriched" "Detected in many" 5 "astrocyte: 38.2;central nervous system macrophage: 130.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 51.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Spleen - Neutrophils_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA028587, HPA061711" Enhanced Supported Vesicles,Centrosome,Mitochondria,Cytosol NA NA 100000 "Cluster 7: Non-specific - Innate immune response" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 19 "Mitochondria, Cytosol" "Vesicles, Centrosome" "HPA028587: , HPA061711: " "unprognostic (1.35e-1)" "unprognostic (1.29e-1)" "unprognostic (1.97e-1)" "potential prognostic unfavorable (6.10e-4)" "unprognostic (5.95e-2)" "potential prognostic favorable (2.29e-5)" "unprognostic (9.30e-2)" "unprognostic (6.58e-2)" "unprognostic (4.00e-2)" "unprognostic (1.63e-2)" "unprognostic (2.52e-2)" "unprognostic (3.13e-2)" "unprognostic (6.18e-2)" "potential prognostic unfavorable (1.44e-4)" "unprognostic (3.33e-2)" "unprognostic (4.24e-3)" "unprognostic (4.16e-3)" "unprognostic (1.49e-1)" "unprognostic (3.23e-2)" "unprognostic (5.30e-2)" "unprognostic (3.77e-2)" "unprognostic (8.60e-3)" "unprognostic (2.33e-2)" "unprognostic (3.02e-2)" "unprognostic (7.87e-2)" "unprognostic (3.04e-2)" "unprognostic (2.73e-1)" "unprognostic (1.90e-1)" "unprognostic (1.90e-1)" "unprognostic (2.53e-1)" "unprognostic (7.37e-2)" HK3 ENSG00000160883 "Hexokinase 3" P52790 5 176880869-176899346 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 122.3;lymphoid tissue: 72.9" "Cell type enhanced" "Detected in some" "Hofbauer cells: 35.9;Kupffer cells: 82.0;Late primary spermatocytes: 17.5;Macrophages: 18.2;Monocyte progenitors: 22.5;monocytes: 56.0;Neutrophil progenitors: 102.7;Neutrophils: 120.4" "Cell type enriched" "Detected in some" 4 "leukocyte: 14.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 571.4" "Group enriched" "Detected in many" 13 "granulocytes: 571.4;monocytes: 201.4" "Group enriched" "Detected in some" 10 "Leukemia: 2.9;Neuroblastoma: 1.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Kidney - Macrophages, Lung - Neutrophils_2, Prostate - Macrophages, Skin - Macrophages, Spleen - Neutrophils_2, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA056743 Enhanced NA NA 2300000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 12 "HPA056743: " "unprognostic (1.42e-1)" "unprognostic (5.65e-2)" "unprognostic (7.17e-2)" "unprognostic (1.00e-2)" "unprognostic (2.29e-1)" "unprognostic (1.61e-1)" "unprognostic (5.57e-3)" "unprognostic (9.59e-2)" "unprognostic (1.42e-1)" "unprognostic (2.14e-1)" "unprognostic (1.02e-1)" "unprognostic (7.64e-2)" "unprognostic (3.40e-2)" "unprognostic (3.27e-2)" "unprognostic (3.92e-2)" "unprognostic (3.39e-2)" "unprognostic (1.20e-1)" "unprognostic (9.19e-2)" "unprognostic (3.14e-3)" "unprognostic (2.84e-2)" "potential prognostic unfavorable (9.70e-4)" "unprognostic (2.42e-2)" "unprognostic (2.04e-1)" "unprognostic (2.97e-1)" "unprognostic (6.40e-2)" "unprognostic (7.59e-2)" "unprognostic (5.29e-2)" HKDC1 "FLJ22761, FLJ37767" ENSG00000156510 "Hexokinase domain containing 1" Q2TB90 10 69220332-69267552 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis "Kinase, Transferase" "Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 50.4;retina: 43.4" "Cell type enriched" "Detected in many" 4 "Müller glia: 1675.6" "Cell type enhanced" "Detected in some" "Bergmann glia: 61.6;ependymal cell: 105.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "memory CD4 T-cell: 3.1;naive CD4 T-cell: 5.8;naive CD8 T-cell: 2.3;T-reg: 5.4" "Lineage enriched" "Detected in single" 23 "T-cells: 5.8" "Cancer enhanced" "Detected in many" "Bile duct cancer: 68.7;Kidney cancer: 74.7" "Kidney - Macrophages, Pancreas - Ductal cells" "Region enhanced" "Detected in many" "cerebral cortex: 11.9" "Low region specificity" "Detected in all" "HPA064198, HPA064230" Enhanced Enhanced Mitochondria No No "Cluster 11: T-cells - Unknown function" "Cluster 42: Retina - Visual perception" "Cluster 46: Brainstem - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 11: Muller glia cells - Retinal homeostasis" 22 Mitochondria "HPA064198: , HPA064230: " "unprognostic (4.11e-2)" "unprognostic (5.09e-3)" "unprognostic (1.90e-1)" "unprognostic (8.18e-3)" "unprognostic (2.47e-1)" "unprognostic (2.75e-1)" "unprognostic (2.73e-1)" "unprognostic (5.71e-2)" "unprognostic (3.21e-2)" "unprognostic (5.88e-2)" "potential prognostic unfavorable (7.91e-4)" "unprognostic (5.55e-3)" "unprognostic (1.44e-1)" "unprognostic (1.83e-1)" "unprognostic (9.50e-2)" "potential prognostic unfavorable (3.73e-4)" "unprognostic (2.87e-3)" "unprognostic (1.67e-1)" "unprognostic (8.64e-2)" "unprognostic (1.01e-3)" "unprognostic (2.21e-1)" "unprognostic (2.67e-2)" "unprognostic (4.48e-2)" "unprognostic (1.90e-2)" "unprognostic (2.41e-1)" "unprognostic (3.35e-1)" "unprognostic (1.97e-3)" "unprognostic (1.50e-1)" HLA-A ENSG00000206503 "Major histocompatibility complex, class I, A" P04439 6 29941260-29949572 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 346.9;Enterocytes: 391.9;Epididymal efferent duct absorptive cells: 304.0;Neutrophils: 349.5;Platelets: 739.3" "Cell type enhanced" "Detected in all" "endothelial cell: 514.2;leukocyte: 779.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - T-cells" CAB078470 Supported "Golgi apparatus,Plasma membrane" NA NA 67000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 9: T-cells - Adaptive immunity: Regulation" 55 "Plasma membrane" "Golgi apparatus" "CAB078470: " "unprognostic (1.22e-2)" "unprognostic (9.01e-3)" "unprognostic (1.46e-1)" "unprognostic (1.90e-1)" "unprognostic (2.55e-2)" "unprognostic (3.43e-2)" "unprognostic (3.00e-1)" "unprognostic (2.25e-1)" "unprognostic (2.70e-3)" "unprognostic (1.51e-1)" "unprognostic (1.73e-1)" "unprognostic (1.38e-1)" "unprognostic (3.38e-1)" "unprognostic (4.62e-2)" "unprognostic (1.53e-1)" "unprognostic (1.35e-3)" "unprognostic (8.98e-2)" "unprognostic (2.76e-1)" "unprognostic (1.79e-2)" "unprognostic (2.29e-1)" "unprognostic (3.94e-1)" "unprognostic (6.79e-2)" "unprognostic (9.77e-2)" "unprognostic (7.55e-2)" "unprognostic (1.14e-2)" "unprognostic (8.64e-2)" "unprognostic (2.63e-1)" "unprognostic (2.15e-1)" "unprognostic (3.21e-1)" HLA-B AS ENSG00000234745 "Major histocompatibility complex, class I, B" P01889 6 31353872-31367067 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 2350.0" "Cell type enhanced" "Detected in many" "Endometrial secretory cells: 193.5;Neutrophils: 267.1;NK-cells: 210.1;Plasma cells: 178.0;Platelets: 301.6;T-cells: 192.0" "Group enriched" "Detected in many" 4 "endothelial cell: 703.3;leukocyte: 1130.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (other), Thyroid gland - T-cells" CAB015418 Enhanced NA NA 84000000 "Cluster 7: Non-specific - Innate immune response" "Cluster 5: Spleen - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 67: Plasma cells - Plasma cell differentiation" 14 "CAB015418: " "unprognostic (2.13e-2)" "unprognostic (3.69e-2)" "unprognostic (4.18e-1)" "unprognostic (1.12e-1)" "unprognostic (2.80e-1)" "unprognostic (7.02e-2)" "unprognostic (2.62e-1)" "unprognostic (6.25e-2)" "unprognostic (3.77e-2)" "unprognostic (2.92e-2)" "unprognostic (7.61e-3)" "unprognostic (1.07e-1)" "unprognostic (1.36e-1)" "unprognostic (6.62e-2)" "unprognostic (3.34e-1)" "unprognostic (1.43e-1)" "unprognostic (5.67e-2)" "unprognostic (1.61e-1)" "unprognostic (1.45e-2)" "unprognostic (3.46e-2)" "unprognostic (7.36e-2)" "unprognostic (1.38e-1)" "unprognostic (2.51e-1)" "unprognostic (1.10e-1)" "unprognostic (3.12e-1)" "unprognostic (8.65e-2)" "unprognostic (4.53e-2)" "unprognostic (2.67e-1)" "unprognostic (1.61e-1)" HLA-C "D6S204, HLA-JY3, PSORS1" ENSG00000204525 "Major histocompatibility complex, class I, C" P10321 6 31268749-31272130 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1377.9" "Cell type enhanced" "Detected in many" "Endometrial secretory cells: 290.7;Extravillous trophoblasts: 165.7;Neutrophils: 236.1;Platelets: 288.5" "Cell type enhanced" "Detected in all" "endothelial cell: 519.5;leukocyte: 747.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 5.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Skeletal muscle - Endothelial cells, Thyroid gland - T-cells" "Intracellular and membrane" Immunity NA NA 80000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 5: Spleen - Immune response" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 102: Non-specific - Mixed function" 117 "unprognostic (2.59e-1)" "unprognostic (1.62e-2)" "unprognostic (2.26e-1)" "unprognostic (3.98e-2)" "unprognostic (4.18e-2)" "unprognostic (7.35e-2)" "unprognostic (2.21e-1)" "unprognostic (1.48e-2)" "unprognostic (7.17e-2)" "unprognostic (1.51e-1)" "unprognostic (1.07e-2)" "unprognostic (2.16e-1)" "unprognostic (1.92e-2)" "unprognostic (3.07e-2)" "unprognostic (1.88e-1)" "unprognostic (1.18e-1)" "unprognostic (1.04e-1)" "unprognostic (1.34e-2)" "unprognostic (1.24e-2)" "unprognostic (2.81e-2)" "unprognostic (4.53e-1)" "unprognostic (1.93e-1)" "unprognostic (1.72e-1)" "unprognostic (8.13e-2)" "unprognostic (6.42e-2)" "unprognostic (2.71e-1)" "unprognostic (8.38e-2)" "unprognostic (7.55e-2)" "unprognostic (1.34e-1)" HLA-DMA "D6S222E, RING6" ENSG00000204257 "Major histocompatibility complex, class II, DM alpha" P28067 6 32948613-32969094 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 119.3" "Cell type enhanced" "Detected in many" "B-cells: 129.8;Breast lactating cells: 144.0;cDC: 733.8;Endometrial secretory cells: 140.7;Enterocytes: 153.4;Fallopian secretory cells: 111.4;Kupffer cells: 262.4;Macrophages: 263.7;Microglia: 112.0;monocytes: 127.5;pDCs: 178.5" "Cell type enriched" "Detected in all" 4 "central nervous system macrophage: 158.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 5 "classical monocyte: 3.8;intermediate monocyte: 3.8;memory B-cell: 6.4;myeloid DC: 7.2;naive B-cell: 6.4;plasmacytoid DC: 5.3" "Group enriched" "Detected in many" 12 "B-cells: 6.4;dendritic cells: 7.2;monocytes: 3.8" "Cancer enhanced" "Detected in many" "Bile duct cancer: 11.7;lymphoma: 15.5" "Adipose visceral - T-cells, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012750, HPA017295" Enhanced Supported Vesicles NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 82: Dendritic cells - Antigen presentation" 4 Vesicles "HPA012750: , HPA017295: " "unprognostic (2.31e-1)" "unprognostic (9.70e-3)" "unprognostic (1.56e-1)" "unprognostic (1.77e-1)" "unprognostic (3.49e-1)" "unprognostic (1.70e-1)" "unprognostic (1.95e-1)" "potential prognostic favorable (3.27e-4)" "unprognostic (4.28e-3)" "unprognostic (3.38e-3)" "unprognostic (2.14e-1)" "unprognostic (7.50e-2)" "unprognostic (1.07e-3)" "unprognostic (4.46e-3)" "unprognostic (3.74e-2)" "unprognostic (3.01e-2)" "unprognostic (1.03e-1)" "unprognostic (2.27e-2)" "unprognostic (6.20e-2)" "unprognostic (1.88e-1)" "unprognostic (3.78e-1)" "unprognostic (1.13e-1)" "unprognostic (2.90e-1)" "unprognostic (1.09e-1)" "unprognostic (2.02e-1)" "unprognostic (2.11e-1)" "unprognostic (1.84e-1)" "unprognostic (5.71e-2)" "unprognostic (3.78e-2)" HLA-DMB "D6S221E, RING7" ENSG00000242574 "Major histocompatibility complex, class II, DM beta" P28068 6 32934629-32941028 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 76.7;lymphoid tissue: 100.7" "Cell type enhanced" "Detected in many" "B-cells: 33.5;cDC: 130.9;Endometrial secretory cells: 30.8;Enterocytes: 54.6;Kupffer cells: 47.1;Macrophages: 54.8;Microglia: 105.2;monocytes: 30.1;pDCs: 23.7" "Cell type enriched" "Detected in many" 7 "central nervous system macrophage: 154.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 6 "B-cells: 129.1;dendritic cells: 85.5;monocytes: 73.9" "Cancer enhanced" "Detected in many" "lymphoma: 16.0;prostate cancer: 10.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Heart muscle - T-cells, Lung - Macrophages, Spleen - B-cells (Spleen), Thyroid gland - T-cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA012298, HPA077524" Supported Supported Vesicles NA NA "Cluster 5: Spleen - Immune response" "Cluster 21: Non-specific - Metabolism" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 82: Dendritic cells - Antigen presentation" 32 Vesicles "HPA012298: , HPA077524: " "unprognostic (2.20e-1)" "unprognostic (7.34e-2)" "unprognostic (1.19e-1)" "unprognostic (1.76e-1)" "unprognostic (3.04e-2)" "unprognostic (2.21e-1)" "unprognostic (4.38e-2)" "unprognostic (3.74e-2)" "unprognostic (9.88e-2)" "unprognostic (1.85e-1)" "unprognostic (1.00e-1)" "unprognostic (5.01e-1)" "unprognostic (9.23e-2)" "unprognostic (2.49e-2)" "unprognostic (3.71e-1)" "unprognostic (1.70e-1)" "unprognostic (1.88e-1)" "unprognostic (4.79e-2)" "unprognostic (2.22e-1)" "unprognostic (4.37e-1)" "unprognostic (9.88e-2)" "unprognostic (1.20e-1)" "unprognostic (2.59e-1)" "unprognostic (1.07e-2)" "unprognostic (2.13e-1)" "unprognostic (2.49e-1)" "unprognostic (5.63e-2)" "unprognostic (8.84e-2)" "unprognostic (2.83e-2)" HLA-DOA "HLA-D0-alpha, HLA-DNA, HLA-DZA" ENSG00000204252 "Major histocompatibility complex, class II, DO alpha" P06340 6 33004182-33009591 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 27.3" "Cell type enhanced" "Detected in some" "B-cells: 6.5;cDC: 4.8;Loop of henle epithelial cells: 1.6;Macrophages: 3.1;Microglia: 20.0;Papillary tip epithelial cells: 4.6;pDCs: 2.1;Renal collecting duct principal cells: 3.9" "Cell type enriched" "Detected in some" 7 "central nervous system macrophage: 26.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 17.8;naive B-cell: 21.1" "Group enriched" "Detected in many" 11 "B-cells: 21.1;dendritic cells: 17.8;monocytes: 6.0" "Cancer enhanced" "Detected in some" "lymphoma: 14.2" "Adipose visceral - T-cells, Heart muscle - T-cells, Lung - T-cells, Prostate - T-cells, Spleen - B-cells (Spleen), Thyroid gland - T-cells" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 4.9" "HPA045038, HPA076922" Enhanced NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 102: Non-specific - Mixed function" 2 "HPA045038: , HPA076922: " "unprognostic (1.24e-1)" "unprognostic (6.97e-2)" "unprognostic (2.34e-1)" "unprognostic (1.78e-1)" "unprognostic (3.55e-1)" "unprognostic (7.25e-2)" "unprognostic (9.28e-2)" "unprognostic (1.08e-1)" "unprognostic (1.14e-1)" "unprognostic (4.04e-2)" "unprognostic (2.33e-1)" "unprognostic (3.00e-2)" "unprognostic (1.02e-1)" "unprognostic (3.11e-2)" "unprognostic (5.29e-2)" "unprognostic (2.70e-1)" "unprognostic (1.14e-1)" "unprognostic (8.64e-2)" "unprognostic (4.23e-2)" "unprognostic (2.79e-1)" "unprognostic (1.32e-1)" "unprognostic (1.83e-1)" "unprognostic (2.78e-2)" "unprognostic (1.52e-2)" "unprognostic (1.37e-1)" "unprognostic (3.70e-2)" "unprognostic (3.54e-2)" "unprognostic (6.78e-2)" "unprognostic (1.77e-1)" HLA-DOB ENSG00000241106 "Major histocompatibility complex, class II, DO beta" P13765 6 32812763-32820466 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "intestine: 18.9;lymphoid tissue: 40.9" "Cell type enhanced" "Detected in some" "Astrocytes: 3.3;B-cells: 5.4;Bergmann glia: 1.0;Microglia: 1.1;Plasma cells: 1.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 18 "memory B-cell: 214.6;naive B-cell: 259.2" "Lineage enriched" "Detected in many" 19 "B-cells: 259.2" "Cancer enriched" "Detected in some" 6 "lymphoma: 17.8" "Minor Salivary Gland - Plasma cells, Spleen - B-cells (Spleen), Stomach - Plasma cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA013846 Enhanced NA NA "Cluster 18: Non-specific - Translation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 102: Non-specific - Mixed function" 1 "HPA013846: " "unprognostic (4.80e-1)" "potential prognostic favorable (3.44e-4)" "unprognostic (5.64e-2)" "unprognostic (3.20e-2)" "unprognostic (2.57e-1)" "unprognostic (5.32e-3)" "unprognostic (2.72e-1)" "unprognostic (9.21e-2)" "unprognostic (1.09e-2)" "unprognostic (1.75e-1)" "unprognostic (2.91e-2)" "unprognostic (1.56e-1)" "unprognostic (5.58e-2)" "unprognostic (1.26e-1)" "unprognostic (4.96e-2)" "unprognostic (2.69e-2)" "unprognostic (5.84e-2)" "unprognostic (3.19e-2)" "unprognostic (2.87e-2)" "unprognostic (1.79e-1)" "unprognostic (1.44e-1)" "unprognostic (2.12e-1)" HLA-DPA1 HLA-DP1A ENSG00000231389 "Major histocompatibility complex, class II, DP alpha 1" P20036 6 33064569-33080775 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 516.7;lymphoid tissue: 570.0" "Cell type enriched" "Detected in many" 4 "cDC: 2885.7" "Cell type enriched" "Detected in many" 4 "central nervous system macrophage: 359.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "classical monocyte: 473.9;intermediate monocyte: 1069.2;memory B-cell: 818.4;myeloid DC: 1726.4;naive B-cell: 800.1;non-classical monocyte: 725.0;plasmacytoid DC: 542.7" "Group enriched" "Detected in all" 9 "B-cells: 818.4;dendritic cells: 1726.4;monocytes: 1069.2" "Cancer enhanced" "Detected in many" "lymphoma: 299.8;Myeloma: 115.4;skin cancer: 120.3" "Adipose visceral - T-cells, Thyroid gland - T-cells" HPA017967 Enhanced Supported Vesicles NA NA 300000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 22: Non-specific - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 82: Dendritic cells - Antigen presentation" 17 Vesicles "HPA017967: " "unprognostic (2.05e-1)" "unprognostic (1.31e-1)" "unprognostic (5.19e-2)" "unprognostic (5.34e-2)" "unprognostic (1.91e-1)" "unprognostic (5.13e-2)" "unprognostic (1.16e-1)" "unprognostic (1.59e-1)" "unprognostic (2.59e-1)" "unprognostic (1.34e-3)" "unprognostic (1.19e-2)" "unprognostic (4.82e-2)" "unprognostic (1.87e-1)" "unprognostic (1.51e-2)" "unprognostic (5.21e-2)" "unprognostic (1.38e-2)" "unprognostic (3.15e-1)" "unprognostic (1.91e-1)" "unprognostic (1.52e-1)" "unprognostic (1.72e-2)" "unprognostic (4.27e-1)" "unprognostic (3.48e-1)" "unprognostic (1.23e-1)" "unprognostic (4.13e-2)" "unprognostic (1.69e-1)" "unprognostic (6.70e-2)" "unprognostic (1.03e-2)" "unprognostic (1.64e-2)" "unprognostic (3.09e-2)" HLA-DPB1 HLA-DP1B ENSG00000223865 "Major histocompatibility complex, class II, DP beta 1" P04440 6 33075990-33089696 "Human disease related genes, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 261.7;lymphoid tissue: 376.0" "Cell type enhanced" "Detected in many" "B-cells: 630.3;cDC: 6181.4;Kupffer cells: 1637.8;Macrophages: 1467.9;monocytes: 551.9;pDCs: 486.5" "Group enriched" "Detected in many" 5 "central nervous system macrophage: 263.9;leukocyte: 90.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 286.9" "Group enriched" "Detected in all" 10 "B-cells: 229.7;dendritic cells: 286.9;monocytes: 138.3" "Group enriched" "Detected in some" 6 "Leukemia: 4.4;lymphoma: 14.2;skin cancer: 3.7" "Adipose visceral - T-cells, Thyroid gland - T-cells" "HPA011078, HPA058509" Enhanced Approved "Nucleoplasm,Cell Junctions" NA NA 420000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 25: Non-specific - Transcription" "Cluster 55: Lymphoma - Immune response" "Cluster 82: Dendritic cells - Antigen presentation" 2 "Cell Junctions" Nucleoplasm "HPA011078: , HPA058509: " "unprognostic (1.26e-1)" "unprognostic (1.10e-1)" "unprognostic (4.25e-2)" "unprognostic (1.64e-1)" "unprognostic (4.34e-1)" "unprognostic (5.96e-2)" "unprognostic (1.65e-1)" "unprognostic (9.00e-2)" "unprognostic (2.62e-1)" "potential prognostic favorable (4.84e-4)" "unprognostic (2.45e-1)" "unprognostic (7.35e-2)" "potential prognostic unfavorable (6.90e-4)" "unprognostic (2.10e-3)" "unprognostic (3.11e-2)" "unprognostic (2.73e-2)" "unprognostic (3.40e-1)" "unprognostic (9.58e-2)" "unprognostic (1.13e-1)" "unprognostic (3.94e-2)" "unprognostic (4.04e-1)" "unprognostic (9.54e-2)" "unprognostic (1.40e-1)" "unprognostic (1.76e-1)" "unprognostic (1.88e-2)" "unprognostic (1.23e-1)" "unprognostic (3.72e-2)" "unprognostic (5.58e-2)" "unprognostic (2.52e-2)" HLA-DQA1 "CELIAC1, HLA-DQA" ENSG00000196735 "Major histocompatibility complex, class II, DQ alpha 1" P01909 6 32628179-32647062 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 314.2;lymphoid tissue: 314.3" "Group enriched" "Detected in many" 4 "B-cells: 437.5;cDC: 1481.0;Kupffer cells: 593.4;Macrophages: 459.8" "Cell type enriched" "Detected in some" 4 "central nervous system macrophage: 107.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 667.5" "Group enriched" "Detected in all" 19 "B-cells: 288.5;dendritic cells: 667.5;monocytes: 257.5" "Cancer enhanced" "Detected in some" "lymphoma: 195.2;skin cancer: 49.0" "Adipose visceral - T-cells, Heart muscle - T-cells, Skin - Langerhans cells, Thyroid gland - T-cells" HPA012315 Enhanced NA NA 610000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 21: Non-specific - Metabolism" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 82: Dendritic cells - Antigen presentation" 3 "HPA012315: " "unprognostic (4.65e-2)" "unprognostic (3.33e-2)" "unprognostic (1.23e-1)" "unprognostic (1.20e-1)" "unprognostic (1.56e-1)" "unprognostic (1.85e-1)" "unprognostic (8.98e-2)" "unprognostic (7.05e-2)" "unprognostic (3.59e-2)" "unprognostic (3.17e-2)" "unprognostic (2.54e-2)" "unprognostic (1.75e-1)" "unprognostic (4.01e-2)" "unprognostic (5.52e-2)" "unprognostic (3.66e-2)" "unprognostic (3.87e-1)" "unprognostic (4.36e-1)" "unprognostic (7.66e-3)" "unprognostic (7.89e-2)" "unprognostic (1.52e-2)" "unprognostic (3.06e-1)" "unprognostic (1.55e-1)" "unprognostic (2.41e-1)" "unprognostic (8.65e-2)" "unprognostic (8.68e-2)" "unprognostic (1.31e-1)" "unprognostic (1.58e-1)" "unprognostic (2.91e-1)" "unprognostic (2.60e-2)" HLA-DQA2 HLA-DXA ENSG00000237541 "Major histocompatibility complex, class II, DQ alpha 2" P01906 6 32741391-32747198 "Human disease related genes, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 21.1;lymphoid tissue: 25.8" "Cell type enhanced" "Detected in some" "B-cells: 9.0;cDC: 62.8;Endometrial secretory cells: 8.4;Macrophages: 13.4;monocytes: 11.9;pDCs: 20.9" "Cell type enriched" "Detected in single" 10 "central nervous system macrophage: 2.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Langerhans cells" NA NA "Cluster 5: Spleen - Immune response" "Cluster 27: Breast cancer - Unknown function" "Cluster 82: Dendritic cells - Antigen presentation" 1 "unprognostic (9.28e-2)" "unprognostic (8.19e-2)" "unprognostic (1.98e-1)" "unprognostic (1.07e-1)" HLA-DQB1 "CELIAC1, HLA-DQB, IDDM1" ENSG00000179344 "Major histocompatibility complex, class II, DQ beta 1" 6 32659467-32668383 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 173.2;lymphoid tissue: 290.6" "Cell type enhanced" "Detected in many" "B-cells: 350.2;cDC: 1347.6;Endometrial secretory cells: 174.4;Enterocytes: 416.3;Kupffer cells: 298.2;Macrophages: 346.8;pDCs: 234.0" "Group enriched" "Detected in many" 8 "central nervous system macrophage: 120.7;leukocyte: 37.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 149.8;intermediate monocyte: 141.0;memory B-cell: 161.5;myeloid DC: 392.1;naive B-cell: 171.4;plasmacytoid DC: 114.8" "Group enriched" "Detected in all" 6 "B-cells: 171.4;dendritic cells: 392.1;monocytes: 149.8" "Cancer enhanced" "Detected in many" "lymphoma: 101.7;skin cancer: 45.4" "Thyroid gland - T-cells" "Low region specificity" "Detected in all" HPA013667 Enhanced Supported "Golgi apparatus,Rods & Rings" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 22: Non-specific - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 82: Dendritic cells - Antigen presentation" 1 "Rods & Rings" "Golgi apparatus" "HPA013667: " "unprognostic (2.46e-2)" "unprognostic (1.84e-3)" "unprognostic (1.41e-1)" "unprognostic (1.20e-1)" "unprognostic (7.33e-2)" "unprognostic (2.18e-1)" "unprognostic (5.69e-3)" "unprognostic (2.53e-1)" "unprognostic (3.50e-1)" "unprognostic (1.30e-1)" "unprognostic (3.32e-2)" "unprognostic (2.73e-1)" "unprognostic (2.24e-2)" "potential prognostic favorable (8.78e-4)" "unprognostic (1.35e-1)" "unprognostic (2.52e-1)" "unprognostic (3.67e-3)" "unprognostic (2.39e-2)" "unprognostic (9.83e-2)" "unprognostic (2.46e-2)" "unprognostic (3.01e-2)" "unprognostic (2.38e-1)" "unprognostic (1.22e-1)" "unprognostic (9.36e-2)" "unprognostic (4.26e-2)" "unprognostic (3.20e-1)" "unprognostic (1.12e-1)" "unprognostic (1.53e-1)" "unprognostic (4.67e-3)" HLA-DQB2 HLA-DXB ENSG00000232629 "Major histocompatibility complex, class II, DQ beta 2" P05538 6 32756098-32763532 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 50.0" "Group enriched" "Detected in some" 4 "cDC: 18.3;Macrophages: 5.8;Suprabasal keratinocytes: 4.8" "Group enriched" "Detected in some" 7 "central nervous system macrophage: 4.1;leukocyte: 1.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.3" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA073187 Enhanced NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 37: Skin - Keratinization" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 82: Dendritic cells - Antigen presentation" "HPA073187: " "unprognostic (4.18e-3)" "unprognostic (1.18e-1)" "unprognostic (5.60e-2)" "unprognostic (1.39e-1)" "unprognostic (5.69e-2)" "unprognostic (6.79e-2)" "unprognostic (5.12e-2)" "unprognostic (1.16e-1)" "unprognostic (3.84e-1)" "unprognostic (1.85e-1)" "unprognostic (3.36e-1)" "unprognostic (1.08e-1)" HLA-DRA HLA-DRA1 ENSG00000204287 "Major histocompatibility complex, class II, DR alpha" P01903 6 32439878-32445046 "Plasma proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 931.1;lymphoid tissue: 1196.6" "Cell type enriched" "Detected in many" 5 "cDC: 2677.3" "Cell type enriched" "Detected in many" 5 "central nervous system macrophage: 734.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 209.9;intermediate monocyte: 408.5;memory B-cell: 380.1;naive B-cell: 419.5;non-classical monocyte: 255.4;plasmacytoid DC: 231.2" "Group enriched" "Detected in all" 5 "B-cells: 419.5;dendritic cells: 231.2;monocytes: 408.5" "Group enriched" "Detected in many" 14 "Leukemia: 103.6;lymphoma: 328.5;Myeloma: 126.2;skin cancer: 86.9" "Adipose visceral - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002798, CAB015402, HPA050162, HPA053176" Enhanced NA NA 1500000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 82: Dendritic cells - Antigen presentation" 63 "CAB002798: , CAB015402: , HPA050162: , HPA053176: " "unprognostic (8.95e-2)" "potential prognostic favorable (1.77e-4)" "unprognostic (2.93e-1)" "unprognostic (7.40e-2)" "unprognostic (4.02e-2)" "unprognostic (7.52e-2)" "unprognostic (2.56e-1)" "unprognostic (8.20e-2)" "unprognostic (2.91e-1)" "unprognostic (2.30e-2)" "unprognostic (2.46e-1)" "unprognostic (6.45e-2)" "unprognostic (9.35e-2)" "unprognostic (4.69e-3)" "unprognostic (3.36e-1)" "unprognostic (5.53e-3)" "unprognostic (1.49e-1)" "unprognostic (2.18e-1)" "unprognostic (1.06e-1)" "unprognostic (6.93e-2)" "unprognostic (1.16e-1)" "unprognostic (2.80e-1)" "unprognostic (1.59e-1)" "unprognostic (3.17e-1)" "unprognostic (8.76e-2)" "unprognostic (1.38e-2)" "unprognostic (1.79e-1)" "unprognostic (7.43e-2)" "unprognostic (8.72e-3)" HLA-DRB1 HLA-DR1B ENSG00000196126 "Major histocompatibility complex, class II, DR beta 1" P01911 6 32577902-32589848 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 554.1;lymphoid tissue: 574.2" "Cell type enhanced" "Detected in many" "B-cells: 580.9;cDC: 4053.3;Endometrial secretory cells: 754.5;Enterocytes: 958.9;Kupffer cells: 757.4;Macrophages: 1240.7;Microglia: 347.5;monocytes: 458.0;pDCs: 530.9" "Cell type enriched" "Detected in many" 4 "central nervous system macrophage: 523.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 655.8" "Group enriched" "Detected in all" 9 "B-cells: 209.8;dendritic cells: 655.8;monocytes: 313.1" "Cancer enhanced" "Detected in many" "lymphoma: 168.4;skin cancer: 100.3" "Thyroid gland - T-cells" "CAB015400, CAB034021, HPA043151" Enhanced NA NA 800000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 21: Non-specific - Metabolism" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 82: Dendritic cells - Antigen presentation" 59 "CAB015400: , CAB034021: , HPA043151: " "unprognostic (5.58e-2)" "unprognostic (2.75e-2)" "unprognostic (1.95e-1)" "unprognostic (3.50e-1)" "unprognostic (8.46e-3)" "unprognostic (6.86e-2)" "unprognostic (6.98e-2)" "unprognostic (1.81e-2)" "unprognostic (6.54e-2)" "unprognostic (6.81e-2)" "unprognostic (1.97e-1)" "unprognostic (2.79e-2)" "unprognostic (2.49e-2)" "unprognostic (1.09e-2)" "unprognostic (1.43e-1)" "unprognostic (1.36e-1)" "unprognostic (2.21e-1)" "unprognostic (3.64e-2)" "unprognostic (2.36e-1)" "unprognostic (3.10e-3)" "unprognostic (2.11e-1)" "unprognostic (1.30e-1)" "unprognostic (1.46e-1)" "unprognostic (1.36e-1)" "unprognostic (1.17e-1)" "unprognostic (9.17e-2)" "unprognostic (2.05e-1)" "unprognostic (2.47e-1)" "unprognostic (7.15e-2)" HLA-DRB5 ENSG00000198502 "Major histocompatibility complex, class II, DR beta 5" Q30154 6 32517353-32530287 "Human disease related genes, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 335.8;lymphoid tissue: 396.9" "Cell type enhanced" "Detected in many" "B-cells: 90.8;cDC: 423.2;Conjunctival goblet cells: 129.1;Endometrial secretory cells: 363.0;Enterocytes: 627.0;Macrophages: 284.1;Microglia: 124.5;monocytes: 110.5;Vascular endothelial cells: 80.8" "Cell type enriched" "Detected in some" 4 "central nervous system macrophage: 203.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "myeloid DC: 62.3" "Group enriched" "Detected in all" 10 "B-cells: 26.2;dendritic cells: 62.3;monocytes: 35.2" "Cancer enhanced" "Detected in many" "lymphoma: 116.2;skin cancer: 63.3" HPA043151 Supported NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 82: Dendritic cells - Antigen presentation" 11 "HPA043151: " "unprognostic (5.29e-2)" "unprognostic (1.93e-3)" "unprognostic (1.30e-1)" "unprognostic (7.83e-2)" "unprognostic (8.87e-2)" "unprognostic (9.38e-2)" "unprognostic (2.20e-2)" "unprognostic (4.50e-3)" "unprognostic (6.34e-2)" "unprognostic (1.80e-2)" "unprognostic (4.03e-1)" "unprognostic (2.42e-2)" "unprognostic (2.93e-2)" "unprognostic (9.70e-3)" "unprognostic (4.43e-1)" "unprognostic (8.44e-2)" "unprognostic (8.83e-2)" "unprognostic (2.75e-1)" "unprognostic (3.76e-2)" "unprognostic (2.78e-2)" "unprognostic (3.33e-1)" "unprognostic (6.59e-2)" "unprognostic (3.34e-1)" "unprognostic (3.18e-1)" "unprognostic (1.45e-1)" "unprognostic (1.21e-2)" "unprognostic (5.97e-2)" "unprognostic (1.46e-1)" "unprognostic (3.42e-2)" HLA-E ENSG00000204592 "Major histocompatibility complex, class I, E" P13747 6 30489509-30494194 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 84.6;Kupffer cells: 90.2;Lymphatic endothelial cells: 85.2;Microglia: 148.7;Neutrophils: 206.6;NK-cells: 96.3;Plasma cells: 120.6;Platelets: 271.6;Vascular endothelial cells: 93.3" "Cell type enhanced" "Detected in many" "endothelial cell: 878.4;leukocyte: 507.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Pituitary gland - Endothelial cells, Skeletal muscle - Endothelial cells, Testis - Endothelial cells" "CAB024589, HPA031454, CAB080329" Enhanced Supported "Vesicles,Plasma membrane" "Secreted to blood" Immunity NA NA 9300000 "Cluster 35: Neutrophils - Protein binding" "Cluster 5: Spleen - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 104: Brain endothelial cells - Blood brain barrier" 17 "Vesicles, Plasma membrane" "CAB024589: , CAB080329: , HPA031454: " "unprognostic (8.84e-2)" "unprognostic (2.32e-1)" "unprognostic (1.55e-2)" "unprognostic (1.02e-2)" "unprognostic (1.80e-1)" "unprognostic (3.49e-2)" "unprognostic (1.12e-1)" "unprognostic (8.91e-2)" "unprognostic (3.55e-2)" "unprognostic (2.67e-3)" "unprognostic (3.62e-2)" "unprognostic (4.22e-2)" "unprognostic (3.06e-2)" "unprognostic (1.12e-2)" "unprognostic (8.08e-2)" "unprognostic (7.44e-2)" "unprognostic (2.09e-1)" "unprognostic (3.59e-1)" "unprognostic (2.14e-1)" "unprognostic (1.95e-1)" "unprognostic (2.92e-2)" "unprognostic (7.15e-2)" "unprognostic (1.69e-1)" "unprognostic (9.26e-2)" "unprognostic (6.09e-2)" "unprognostic (4.04e-2)" "unprognostic (4.87e-3)" "unprognostic (1.57e-2)" "unprognostic (1.86e-2)" HLA-F ENSG00000204642 "Major histocompatibility complex, class I, F" P30511 6 29722775-29738528 "Plasma proteins, Predicted membrane proteins" Immunity "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 172.8" "Cell type enhanced" "Detected in many" "Colonocytes: 90.5;Enterocytes: 265.4;Foveolar cells: 104.6;Goblet cells: 86.1;NK-cells: 136.9;Platelets: 132.1;T-cells: 128.5" "Cell type enhanced" "Detected in many" "endothelial cell: 81.5;leukocyte: 139.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose visceral - T-cells, Lung - NK-cells (Lung), Prostate - T-cells, Thyroid gland - T-cells" NA NA "Cluster 5: Spleen - Immune response" "Cluster 7: Non-specific - Ribosome" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 4 "unprognostic (3.57e-2)" "unprognostic (1.54e-1)" "unprognostic (7.92e-2)" "unprognostic (3.02e-1)" "unprognostic (8.18e-2)" "unprognostic (4.53e-2)" "unprognostic (3.89e-1)" "unprognostic (3.14e-1)" "unprognostic (4.53e-1)" "unprognostic (7.58e-3)" "unprognostic (2.50e-1)" "unprognostic (2.59e-2)" "unprognostic (1.26e-1)" "unprognostic (2.04e-1)" "unprognostic (2.00e-1)" "unprognostic (5.79e-3)" "unprognostic (4.68e-2)" "unprognostic (1.49e-1)" "unprognostic (3.73e-3)" "unprognostic (1.94e-1)" "unprognostic (3.25e-1)" "unprognostic (3.19e-1)" "unprognostic (1.74e-1)" "unprognostic (1.28e-1)" "unprognostic (4.75e-3)" "unprognostic (5.09e-2)" "unprognostic (1.02e-1)" "unprognostic (2.07e-2)" "unprognostic (6.88e-2)" HLA-G ENSG00000204632 "Major histocompatibility complex, class I, G" P17693 6 29826967-29831125 "Cancer-related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Immunity "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "pituitary gland: 13.7;placenta: 10.5" "Cell type enriched" "Detected in some" 24 "Extravillous trophoblasts: 714.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney Renal Clear Cell Carcinoma (TCGA): 5.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lung cancer: 1.1" "Pituitary gland - Gonadotropes, Testis - Late spermatids" CAB016158 Enhanced "Secreted to blood" Immunity NA NA 32800000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 70 "CAB016158: " "unprognostic (8.58e-2)" "unprognostic (3.61e-2)" "unprognostic (2.16e-1)" "unprognostic (7.49e-2)" "unprognostic (1.18e-1)" "unprognostic (3.97e-1)" "unprognostic (6.37e-2)" "unprognostic (6.21e-2)" "unprognostic (3.02e-1)" HLCS HCS ENSG00000159267 "Holocarboxylase synthetase" P50747 21 36748626-36990236 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ligase, Multifunctional enzyme" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gonadotrophs: 469.5;Lactotrophs: 410.5;Retinal pigment epithelial cells: 571.2;Somatotrophs: 396.5;Thyrotrophs: 516.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Minor Salivary Gland - Smooth muscle cells, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017379 Approved Approved Cytosol NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 70: DU4475 - Unknown function" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 12 Cytosol "HPA017379: " "unprognostic (1.01e-1)" "potential prognostic unfavorable (5.56e-4)" "unprognostic (1.62e-1)" "unprognostic (8.96e-2)" "unprognostic (4.85e-2)" "unprognostic (5.07e-2)" "unprognostic (2.62e-1)" "unprognostic (1.35e-3)" "unprognostic (1.53e-2)" "unprognostic (9.00e-3)" "unprognostic (4.02e-3)" "unprognostic (1.61e-1)" "unprognostic (5.02e-2)" "unprognostic (1.35e-1)" "unprognostic (1.28e-1)" "unprognostic (1.04e-1)" "unprognostic (2.45e-1)" "unprognostic (1.43e-1)" "unprognostic (1.98e-2)" "unprognostic (6.20e-2)" "unprognostic (3.31e-1)" "unprognostic (1.45e-1)" "unprognostic (2.46e-1)" "unprognostic (3.08e-2)" "unprognostic (9.89e-3)" "unprognostic (8.80e-2)" "unprognostic (1.35e-2)" "unprognostic (9.47e-2)" "unprognostic (4.34e-2)" "unprognostic (3.29e-3)" "unprognostic (2.78e-1)" HLF MGC33822 ENSG00000108924 "HLF transcription factor, PAR bZIP family member" Q16534 17 55264960-55325187 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 114.4" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 124.7;Hematopoietic stem cells: 119.9;Hepatocytes: 263.7;Müller glia: 94.1;Renal connecting tubule cells: 111.5;Retinal amacrine cells: 206.3;Retinal bipolar cells: 196.0;Retinal horizontal cells: 96.2;Thyrotrophs: 95.2" "Cell type enhanced" "Detected in all" "endothelial cell: 472.6" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 23.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 14.5" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA068156, HPA071210" Enhanced Nucleoplasm Yes NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 18: Liver cancer - Metabolism" "Cluster 104: Brain endothelial cells - Blood brain barrier" 6 Nucleoplasm "HPA068156: , HPA071210: " "unprognostic (7.70e-2)" "unprognostic (7.94e-2)" "unprognostic (1.67e-2)" "unprognostic (2.23e-1)" "unprognostic (2.38e-1)" "unprognostic (3.19e-1)" "unprognostic (1.59e-3)" "unprognostic (3.60e-2)" "potential prognostic favorable (8.30e-10)" "unprognostic (3.40e-3)" "unprognostic (1.49e-3)" "unprognostic (5.34e-3)" "unprognostic (1.04e-1)" "potential prognostic favorable (2.03e-4)" "unprognostic (4.47e-2)" "unprognostic (4.74e-3)" "potential prognostic favorable (1.06e-5)" "unprognostic (1.64e-3)" "unprognostic (1.17e-1)" "unprognostic (2.26e-1)" "potential prognostic favorable (1.36e-4)" "unprognostic (1.09e-2)" "unprognostic (2.07e-1)" "unprognostic (2.20e-2)" HLTF "HIP116A, HLTF1, RNF80, SMARCA3, SNF2L3" ENSG00000071794 "Helicase like transcription factor" Q14527 3 149030127-149086554 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Transcription, Ubl conjugation pathway" "Activator, Chromatin regulator, DNA-binding, Helicase, Hydrolase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early primary spermatocytes: 202.7;Erythrocyte progenitors: 198.2;Sertoli cells: 329.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015284, HPA049001" Uncertain Enhanced Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 24 Nucleoplasm "HPA015284: , HPA049001: " "unprognostic (9.32e-2)" "unprognostic (2.05e-2)" "unprognostic (5.28e-2)" "unprognostic (3.11e-1)" "unprognostic (3.04e-1)" "unprognostic (4.14e-3)" "unprognostic (3.92e-1)" "unprognostic (1.01e-2)" "unprognostic (1.66e-1)" "potential prognostic unfavorable (9.43e-4)" "potential prognostic favorable (7.14e-4)" "unprognostic (2.01e-1)" "unprognostic (1.84e-1)" "unprognostic (8.08e-3)" "unprognostic (2.38e-3)" "unprognostic (2.54e-2)" "unprognostic (8.58e-2)" "unprognostic (1.98e-1)" "unprognostic (7.22e-2)" "unprognostic (5.39e-2)" "unprognostic (2.92e-3)" "unprognostic (2.71e-3)" "unprognostic (2.18e-1)" "unprognostic (5.23e-2)" "unprognostic (1.98e-1)" "unprognostic (5.61e-2)" "unprognostic (3.78e-2)" "unprognostic (1.31e-1)" "unprognostic (1.47e-1)" "unprognostic (9.38e-2)" "unprognostic (3.45e-1)" HLX "HB24, HLX1" ENSG00000136630 "H2.0 like homeobox" Q14774 1 220879431-220885059 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 86.3" "Cell type enhanced" "Detected in some" "cDC: 16.1;Fallopian tube ciliated cells: 19.3;Hepatic stellate cells: 25.8;Hofbauer cells: 62.8;Kupffer cells: 16.4;Monocyte progenitors: 18.7;monocytes: 31.0;Neutrophil progenitors: 48.9;Neutrophils: 68.9;Vascular endothelial cells: 28.7" "Cell type enriched" "Detected in some" 5 "endothelial cell: 13.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 66.9;neutrophil: 58.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 66.9" "Cancer enhanced" "Detected in many" "Leukemia: 23.2" "Breast - Endothelial cells, Liver - Hepatocytes, Prostate - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA005968 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 15: Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 12 "Nucleoplasm, Cytosol" "HPA005968: " "unprognostic (2.38e-1)" "unprognostic (1.15e-1)" "potential prognostic favorable (7.92e-5)" "unprognostic (2.94e-2)" "unprognostic (2.31e-3)" "unprognostic (1.71e-2)" "unprognostic (3.75e-2)" "unprognostic (3.99e-2)" "unprognostic (3.37e-1)" "unprognostic (3.27e-1)" "unprognostic (4.29e-1)" "unprognostic (7.73e-2)" "unprognostic (2.88e-2)" "unprognostic (7.59e-3)" "potential prognostic favorable (1.71e-4)" "unprognostic (2.74e-2)" "unprognostic (1.28e-1)" "unprognostic (2.13e-2)" "unprognostic (1.02e-1)" "unprognostic (2.49e-1)" "unprognostic (1.40e-1)" "unprognostic (1.37e-1)" "unprognostic (2.57e-2)" "unprognostic (2.67e-2)" "unprognostic (4.35e-2)" "unprognostic (1.60e-2)" "unprognostic (7.88e-2)" "unprognostic (1.11e-2)" "unprognostic (1.01e-1)" "unprognostic (6.17e-2)" "unprognostic (2.57e-1)" HM13 "dJ324O17.1, H13, IMP1, IMPAS, PSENL3, PSL3, SPP, SPPL1" ENSG00000101294 "Histocompatibility minor 13" Q8TCT9 20 31514410-31577923 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1457.2;Plasma cells: 496.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045089, HPA056062" Enhanced Supported "Endoplasmic reticulum" NA NA 24000 "Cluster 29: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 15: Kidney cancer - Membrane components" "Cluster 8: Non-specific - Secretory pathway" 12 "Endoplasmic reticulum" "HPA045089: , HPA056062: " "unprognostic (1.68e-1)" "unprognostic (2.25e-2)" "unprognostic (4.50e-1)" "potential prognostic unfavorable (1.43e-4)" "unprognostic (4.09e-1)" "unprognostic (1.16e-1)" "unprognostic (1.09e-1)" "unprognostic (1.56e-1)" "unprognostic (2.97e-2)" "unprognostic (4.30e-2)" "validated prognostic unfavorable (9.90e-4)" "validated prognostic unfavorable (5.22e-5)" "unprognostic (3.05e-2)" "validated prognostic unfavorable (2.81e-4)" "validated prognostic unfavorable (2.42e-5)" "unprognostic (6.66e-2)" "unprognostic (3.97e-2)" "unprognostic (1.36e-3)" "unprognostic (5.77e-2)" "unprognostic (1.70e-2)" "unprognostic (6.69e-2)" "unprognostic (7.79e-2)" "unprognostic (2.04e-2)" "unprognostic (1.59e-1)" "unprognostic (1.42e-2)" "unprognostic (1.35e-2)" "unprognostic (5.85e-2)" "unprognostic (2.21e-1)" "unprognostic (1.37e-2)" "unprognostic (2.49e-2)" "unprognostic (3.85e-2)" HMBOX1 "FLJ21616, HNF1LA, HOT1, PBHNF" ENSG00000147421 "Homeobox containing 1" Q6NT76 8 28890395-29064764 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 456.2;Pituicytes/FSCs: 386.5;Renal collecting duct intercalated cells: 419.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055855, HPA058586, CAB070418" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" Yes No "Cluster 20: Non-specific - DNA binding" "Cluster 40: Non-specific - Mixed function" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 47: Leukemia - Hemostasis" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 84 Nucleoplasm "Nuclear bodies, Cytosol" "CAB070418: , HPA055855: , HPA058586: " "unprognostic (2.15e-1)" "unprognostic (2.51e-1)" "unprognostic (5.11e-2)" "unprognostic (1.44e-1)" "unprognostic (1.26e-2)" "unprognostic (2.24e-1)" "unprognostic (8.34e-2)" "unprognostic (5.77e-3)" "unprognostic (2.14e-1)" "unprognostic (1.46e-2)" "validated prognostic favorable (1.27e-4)" "validated prognostic favorable (8.19e-5)" "unprognostic (2.15e-1)" "unprognostic (2.37e-2)" "unprognostic (2.30e-1)" "unprognostic (1.53e-1)" "unprognostic (6.41e-2)" "unprognostic (3.41e-1)" "unprognostic (2.27e-1)" "unprognostic (1.07e-1)" "unprognostic (1.09e-2)" "unprognostic (1.35e-2)" "unprognostic (5.12e-2)" "unprognostic (2.67e-2)" "unprognostic (2.63e-2)" "unprognostic (2.93e-1)" "unprognostic (5.81e-2)" "unprognostic (3.86e-1)" "unprognostic (2.00e-2)" "unprognostic (5.39e-2)" HMBS "PBGD, PORC, UPS" ENSG00000256269 "Hydroxymethylbilane synthase" P08397 11 119084866-119093834 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Heme biosynthesis, Porphyrin biosynthesis" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "bone marrow: 160.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 69.1;Erythrocyte progenitors: 274.0;Erythrocytes: 181.6;Esophageal basal cells: 54.6;Extravillous trophoblasts: 68.4;Migrating cytotrophoblasts: 65.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006114, HPA050659" Supported Approved "Lipid droplets" NA NA 5100000 "Cluster 13: Non-specific - Mitochondria" "Cluster 15: Bone marrow - Innate immune response" "Cluster 27: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 3 "Lipid droplets" "HPA006114: , HPA050659: " "unprognostic (4.76e-2)" "unprognostic (1.34e-1)" "unprognostic (3.26e-1)" "unprognostic (4.90e-2)" "unprognostic (3.41e-1)" "unprognostic (2.00e-1)" "unprognostic (3.45e-1)" "unprognostic (3.51e-1)" "unprognostic (4.08e-2)" "potential prognostic unfavorable (1.09e-4)" "unprognostic (2.42e-3)" "potential prognostic unfavorable (8.59e-5)" "potential prognostic favorable (3.89e-4)" "unprognostic (1.92e-3)" "potential prognostic unfavorable (7.38e-4)" "potential prognostic unfavorable (1.59e-4)" "unprognostic (2.57e-2)" "unprognostic (5.27e-2)" "unprognostic (1.29e-1)" "unprognostic (1.39e-2)" "unprognostic (1.67e-1)" "potential prognostic unfavorable (3.35e-4)" "unprognostic (3.87e-2)" "unprognostic (2.62e-2)" "unprognostic (4.77e-2)" "unprognostic (1.29e-1)" "unprognostic (6.51e-2)" "unprognostic (5.97e-2)" "unprognostic (3.14e-2)" "unprognostic (6.00e-2)" "unprognostic (3.17e-2)" HMCES "C3orf37, DC12, SRAPD1" ENSG00000183624 "5-hydroxymethylcytosine binding, ES cell specific" Q96FZ2 3 129278828-129306186 "Predicted intracellular proteins" "DNA damage" "DNA-binding, Hydrolase, Lyase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early primary spermatocytes: 179.1;Epididymal basal cells: 133.5;Plasma cells: 225.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044968 Enhanced Approved Nucleoplasm NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 1: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 78: Plasma cells - Antibody production & ER-stress response" 4 Nucleoplasm "HPA044968: " "unprognostic (1.45e-1)" "unprognostic (7.17e-2)" "unprognostic (3.15e-2)" "unprognostic (1.13e-1)" "unprognostic (2.24e-2)" "unprognostic (3.27e-1)" "potential prognostic favorable (1.74e-4)" "unprognostic (1.85e-1)" "potential prognostic unfavorable (5.08e-4)" "unprognostic (1.22e-3)" "potential prognostic favorable (8.09e-4)" "unprognostic (1.93e-1)" "unprognostic (1.56e-3)" "unprognostic (1.27e-2)" "unprognostic (1.22e-1)" "unprognostic (2.96e-1)" "unprognostic (1.27e-1)" "unprognostic (5.44e-3)" "unprognostic (7.52e-2)" "potential prognostic unfavorable (3.98e-4)" "unprognostic (2.11e-1)" "unprognostic (1.60e-2)" "unprognostic (2.07e-2)" "unprognostic (1.94e-3)" "unprognostic (2.13e-1)" "unprognostic (5.31e-3)" "unprognostic (1.65e-2)" "unprognostic (4.05e-2)" "unprognostic (4.33e-1)" HMCN1 "ARMD1, FBLN6, FIBL-6, FIBL6" ENSG00000143341 "Hemicentin 1" Q96RW7 1 185734391-186190949 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cell cycle, Cell division, Sensory transduction, Vision" "Age-related macular degeneration, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "blood vessel: 66.0;lung: 19.4" "Cell type enhanced" "Detected in many" "Breast lactating cells: 132.6;Distal convoluted tubule cells: 252.6;Fibro-adipogenic progenitors: 371.7;Lacrimal acinar cells: 190.2;Lymphatic endothelial cells: 148.6;Melanocytes: 210.6;Pituicytes/FSCs: 763.6;Retinal horizontal cells: 236.4;Salivary duct cells: 252.3;Schwann cells: 170.3;Transitional alveolar cells: 244.2;Vascular endothelial cells: 221.9" "Cell type enriched" "Detected in many" 5 "endothelial cell: 397.0" "Cancer enriched" "Detected in many" 8 "Skin Cutaneous Melanoma (TCGA): 77.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 64.8;skin cancer: 50.9" "Adrenal gland - Fibroblasts, Colon - Enteric glia cells, Pancreas - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Fibroblasts" "Not detected" "Not detected" "Region enhanced" "Detected in many" "olfactory bulb: 13.2" "HPA008220, HPA051677" Uncertain Approved "Golgi apparatus,Cytosol" "Secreted to extracellular matrix" Other NA NA 7400000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 49: Hindbrain - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 1 "Golgi apparatus, Cytosol" "HPA008220: , HPA051677: " "unprognostic (1.74e-1)" "unprognostic (1.60e-1)" "unprognostic (2.91e-1)" "unprognostic (4.17e-2)" "unprognostic (3.18e-2)" "unprognostic (8.82e-3)" "unprognostic (4.47e-2)" "unprognostic (2.14e-1)" "unprognostic (1.08e-1)" "unprognostic (1.50e-1)" "validated prognostic favorable (8.15e-9)" "validated prognostic favorable (8.53e-4)" "unprognostic (2.31e-1)" "unprognostic (4.25e-3)" "unprognostic (2.14e-2)" "unprognostic (9.68e-2)" "unprognostic (2.69e-2)" "unprognostic (1.72e-1)" "unprognostic (4.84e-2)" "unprognostic (8.12e-2)" "unprognostic (2.77e-1)" "unprognostic (2.71e-2)" "unprognostic (1.34e-1)" "unprognostic (8.02e-2)" "unprognostic (4.53e-2)" "unprognostic (1.74e-2)" "unprognostic (3.72e-2)" "unprognostic (2.00e-2)" "unprognostic (1.04e-1)" "unprognostic (9.44e-2)" HMCN2 "DKFZp434P0216, FLJ23816" ENSG00000148357 "Hemicentin 2" Q8NDA2 9 130265760-130434123 "Predicted intracellular proteins, Predicted secreted proteins" "Sensory transduction" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 21.4;intestine: 37.0;skeletal muscle: 23.4" "Group enriched" "Detected in many" 12 "Fibro-adipogenic progenitors: 521.0;Myosatellite cells: 810.8" "Cell type enhanced" "Detected in many" "splatter: 17.0" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "pons: 9.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 5.4;Sarcoma: 3.1" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Adrenal gland - Smooth muscle cells, Minor Salivary Gland - Fibroblasts, Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA053903, HPA070647" Enhanced Approved Vesicles "Secreted to extracellular matrix" Other NA NA 12000000 "Cluster 25: Non-specific - Basic cellular processes" "Cluster 43: Hindbrain - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 108: Fibroblasts - ECM organization" Vesicles "HPA053903: , HPA070647: " "unprognostic (3.39e-1)" "potential prognostic favorable (3.12e-6)" "unprognostic (3.87e-2)" "unprognostic (3.74e-1)" "unprognostic (5.81e-3)" "unprognostic (3.49e-2)" "unprognostic (1.87e-1)" "unprognostic (3.82e-1)" "potential prognostic unfavorable (3.60e-5)" "unprognostic (3.51e-2)" "unprognostic (1.17e-2)" "unprognostic (3.13e-1)" "unprognostic (2.55e-1)" "unprognostic (2.62e-2)" "unprognostic (4.01e-3)" "unprognostic (1.23e-1)" "potential prognostic unfavorable (7.01e-4)" HMG20A "FLJ10739, HMGX1, HMGXB1" ENSG00000140382 "High mobility group 20A" Q9NP66 15 77420412-77485607 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 198.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007685, HPA008126" Supported Approved Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 61: Non-specific - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 58: Non-specific - Nuclear processes" "Cluster 55: Myocytes - Oxidative muscle function" 109 Nucleoplasm "HPA007685: , HPA008126: " "unprognostic (8.39e-2)" "unprognostic (2.26e-1)" "unprognostic (3.84e-1)" "unprognostic (8.31e-3)" "unprognostic (4.22e-2)" "unprognostic (2.93e-1)" "unprognostic (2.26e-1)" "potential prognostic favorable (3.93e-4)" "unprognostic (3.82e-2)" "unprognostic (3.27e-1)" "potential prognostic favorable (1.90e-5)" "unprognostic (3.69e-3)" "unprognostic (3.08e-1)" "unprognostic (1.18e-1)" "unprognostic (1.04e-1)" "unprognostic (3.45e-1)" "unprognostic (1.13e-1)" "unprognostic (1.65e-1)" "unprognostic (1.60e-1)" "unprognostic (1.16e-1)" "unprognostic (1.29e-1)" "unprognostic (1.69e-1)" "unprognostic (6.23e-2)" "unprognostic (1.30e-1)" "unprognostic (4.26e-2)" "unprognostic (2.65e-1)" "unprognostic (3.90e-1)" "unprognostic (3.01e-1)" "unprognostic (1.72e-1)" "unprognostic (1.08e-1)" "unprognostic (2.56e-1)" HMG20B "BRAF25, BRAF35, HMGX2, HMGXB2, SMARCE1r, SOXL" ENSG00000064961 "High mobility group 20B" Q9P0W2 19 3572777-3579088 "Predicted intracellular proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 366.7;Melanocytes: 252.8;Migrating cytotrophoblasts: 190.3;Platelets: 359.3;Syncytiotrophoblasts: 409.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050220, HPA053157, HPA069832" Approved Enhanced Nucleoplasm NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." 40 Nucleoplasm "HPA050220: , HPA053157: , HPA069832: " "unprognostic (1.34e-2)" "unprognostic (2.42e-1)" "unprognostic (1.39e-2)" "unprognostic (4.10e-1)" "unprognostic (1.73e-1)" "unprognostic (8.13e-2)" "unprognostic (6.08e-3)" "unprognostic (2.25e-2)" "unprognostic (8.22e-2)" "unprognostic (3.01e-2)" "unprognostic (3.51e-2)" "unprognostic (1.38e-1)" "potential prognostic favorable (4.24e-5)" "unprognostic (1.13e-1)" "unprognostic (1.31e-1)" "unprognostic (1.91e-2)" "unprognostic (3.10e-2)" "unprognostic (2.07e-2)" "unprognostic (1.18e-2)" "unprognostic (2.34e-1)" "unprognostic (8.82e-2)" "unprognostic (1.32e-1)" "unprognostic (4.33e-1)" "unprognostic (1.36e-1)" "unprognostic (1.51e-1)" "unprognostic (1.00e-1)" "unprognostic (2.74e-1)" "unprognostic (4.30e-2)" "potential prognostic favorable (8.26e-4)" "unprognostic (1.76e-1)" "potential prognostic favorable (6.00e-4)" HMGA1 HMGIY ENSG00000137309 "High mobility group AT-hook 1" P17096 6 34236873-34246231 "Cancer-related genes, Disease related genes, Essential proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 268.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1095.7;Epididymal basal cells: 569.1;Esophageal apical cells: 2097.9;Esophageal basal cells: 594.6;Extravillous trophoblasts: 719.5;Gastric progenitor cells: 480.6;Migrating cytotrophoblasts: 1124.5;Paneth cells: 526.0;Syncytiotrophoblasts: 789.5" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 1790.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Spleen - Mitotic cells (Spleen), Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA065612, HPA068442" Enhanced Supported "Nucleoplasm,Nuclear membrane,Cytosol" NA NA 88000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 84: Apical squamous epithelium - Cornification" 217 "Nucleoplasm, Nuclear membrane" Cytosol "HPA065612: , HPA068442: " "unprognostic (2.01e-1)" "unprognostic (1.88e-1)" "unprognostic (5.94e-1)" "unprognostic (2.53e-2)" "unprognostic (1.31e-1)" "unprognostic (8.63e-2)" "unprognostic (2.50e-1)" "unprognostic (2.08e-1)" "unprognostic (1.43e-3)" "unprognostic (3.19e-2)" "unprognostic (2.31e-2)" "unprognostic (8.78e-2)" "unprognostic (3.17e-2)" "validated prognostic unfavorable (1.03e-6)" "validated prognostic unfavorable (6.28e-7)" "potential prognostic unfavorable (5.09e-5)" "unprognostic (2.57e-3)" "unprognostic (6.63e-2)" "unprognostic (4.83e-2)" "unprognostic (7.84e-2)" "unprognostic (3.31e-1)" "potential prognostic unfavorable (7.18e-4)" "unprognostic (5.75e-3)" "unprognostic (3.16e-2)" "unprognostic (1.47e-1)" "unprognostic (1.39e-1)" "unprognostic (5.20e-2)" "unprognostic (8.95e-3)" "unprognostic (2.58e-1)" "unprognostic (2.18e-1)" "unprognostic (7.14e-2)" HMGA2 "BABL, HMGIC, LIPO" ENSG00000149948 "High mobility group AT-hook 2" P52926 12 65824460-65966291 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Cell cycle, Cell division, DNA condensation, Growth regulation, Mitosis, Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant, Dwarfism, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.6;testis: 3.6" "Cell type enhanced" "Detected in many" "Endometrial secretory cells: 167.9;Erythrocyte progenitors: 149.9;Granulosa cells: 85.2;Hematopoietic stem cells: 427.5;Megakaryocyte progenitors: 108.4;Megakaryocyte-Erythroid progenitors: 153.6;Pituicytes/FSCs: 455.3" "Cell type enhanced" "Detected in some" "astrocyte: 11.4;deep-layer near-projecting: 30.0;ependymal cell: 18.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.5" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "CAB017809, HPA039076" Approved Supported "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 44: Bone marrow - Nuclear processes" "Cluster 48: Non-specific - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 23 "Nucleoplasm, Nucleoli, Nucleoli rim" "CAB017809: , HPA039076: " "unprognostic (4.26e-3)" "unprognostic (5.74e-2)" "unprognostic (1.34e-1)" "unprognostic (2.19e-1)" "unprognostic (2.33e-1)" "unprognostic (7.41e-3)" "unprognostic (4.73e-2)" "unprognostic (2.57e-3)" "unprognostic (2.51e-2)" "potential prognostic unfavorable (2.64e-7)" "unprognostic (2.39e-1)" "unprognostic (9.77e-3)" "unprognostic (4.69e-2)" "unprognostic (6.43e-3)" "unprognostic (2.79e-3)" "unprognostic (2.36e-3)" "unprognostic (1.29e-1)" "unprognostic (5.64e-2)" "unprognostic (1.66e-1)" "unprognostic (7.93e-2)" "validated prognostic unfavorable (2.74e-5)" "validated prognostic unfavorable (2.00e-6)" "unprognostic (1.26e-1)" "unprognostic (1.56e-1)" "unprognostic (1.56e-2)" "unprognostic (1.09e-1)" "unprognostic (2.53e-1)" "unprognostic (2.97e-2)" "unprognostic (1.25e-1)" HMGB1 "DKFZp686A04236, HMG1, HMG3, SBP-1" ENSG00000189403 "High mobility group box 1" P09429 13 30456704-30617597 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Autophagy, Chemotaxis, DNA damage, DNA recombination, DNA repair, Host-virus interaction, Immunity, Inflammatory response, Innate immunity" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythrocyte progenitors: 1881.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA003506, CAB005873, HPA073663" Supported Supported Nucleoplasm "Secreted to blood" Immunity NA NA 1500000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 97 Nucleoplasm "CAB005873: , HPA003506: , HPA073663: " "unprognostic (4.29e-1)" "unprognostic (1.76e-1)" "unprognostic (1.57e-1)" "unprognostic (1.58e-3)" "unprognostic (3.77e-1)" "unprognostic (1.50e-1)" "unprognostic (2.67e-1)" "unprognostic (9.94e-2)" "unprognostic (3.54e-2)" "unprognostic (3.79e-2)" "potential prognostic favorable (1.01e-4)" "unprognostic (8.80e-3)" "unprognostic (2.48e-1)" "unprognostic (1.32e-3)" "potential prognostic unfavorable (2.07e-5)" "potential prognostic unfavorable (2.70e-4)" "unprognostic (1.89e-2)" "unprognostic (2.74e-1)" "unprognostic (1.30e-1)" "unprognostic (2.27e-1)" "unprognostic (1.39e-1)" "validated prognostic unfavorable (5.41e-4)" "validated prognostic unfavorable (7.67e-4)" "unprognostic (3.29e-2)" "unprognostic (1.25e-1)" "unprognostic (7.67e-2)" "unprognostic (1.53e-2)" "unprognostic (4.46e-2)" "unprognostic (2.19e-1)" "unprognostic (4.72e-3)" "unprognostic (4.66e-2)" HMGB1P1 "HMG1L1, HMG1L7, HMGB1L1" ENSG00000124097 "High mobility group box 1 pseudogene 1" B2RPK0 20 57487959-57495366 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "choroid plexus: 1.1" "Group enriched" "Detected in many" 8 "Megakaryocytes: 61.8;Tuft cells: 126.8" "Cell type enhanced" "Detected in single" "ependymal cell: 2.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" HPA073663 Approved Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 17: Choroid plexus - Cilium" "Cluster 24: Non-specific - Unknown function" "Cluster 95: Tuft cells - Chemosensory signaling" 6 Nucleoplasm "HPA073663: " HMGB2 HMG2 ENSG00000164104 "High mobility group box 2" P26583 4 173331376-173334432 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Chemotaxis, DNA recombination, Immunity, Inflammatory response, Innate immunity, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 12 "bone marrow: 2214.7;lymphoid tissue: 874.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 540.2;Early primary spermatocytes: 646.4;Enteric transient amplifying cells: 659.0;Erythrocyte progenitors: 1125.5;Extravillous trophoblasts: 1000.3;Gastric progenitor cells: 638.3;Megakaryocyte progenitors: 538.7;Migrating cytotrophoblasts: 700.1;Monocyte progenitors: 1546.1;Neutrophil progenitors: 1076.2;Neutrophils: 1240.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 802.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003506, CAB037206, HPA053314, HPA073663" Enhanced Supported "Nucleoplasm,Nucleoli,Principal piece,Annulus" "Secreted to blood" Transcription NA Yes 830000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 111 Nucleoplasm "Nucleoli, Principal piece, Annulus" "CAB037206: , HPA003506: , HPA053314: , HPA073663: " "unprognostic (1.74e-1)" "unprognostic (3.04e-1)" "unprognostic (1.73e-1)" "unprognostic (5.00e-2)" "unprognostic (4.10e-1)" "unprognostic (1.30e-1)" "unprognostic (1.19e-1)" "unprognostic (1.27e-1)" "unprognostic (4.23e-2)" "unprognostic (5.70e-3)" "unprognostic (3.08e-3)" "unprognostic (3.34e-1)" "potential prognostic unfavorable (3.09e-4)" "validated prognostic unfavorable (1.02e-6)" "validated prognostic unfavorable (7.88e-5)" "unprognostic (9.19e-3)" "potential prognostic unfavorable (1.05e-4)" "unprognostic (1.34e-2)" "unprognostic (6.93e-2)" "unprognostic (7.87e-2)" "unprognostic (1.83e-2)" "unprognostic (1.18e-3)" "unprognostic (7.28e-2)" "unprognostic (1.48e-1)" "unprognostic (1.37e-1)" "unprognostic (2.45e-2)" "unprognostic (1.65e-2)" "unprognostic (9.39e-2)" "unprognostic (1.28e-1)" "unprognostic (9.37e-2)" "unprognostic (2.63e-1)" HMGB3 "HMG2A, HMG4, MGC90319" ENSG00000029993 "High mobility group box 3" O15347 X 150980509-150990771 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity, Transcription, Transcription regulation" DNA-binding Microphthalmia "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 128.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 372.1;Extravillous trophoblasts: 1129.9;Migrating cytotrophoblasts: 938.0;Oocytes: 396.0;Respiratory deuterosomal cells: 268.5;Respiratory ionocytes: 281.9;Syncytiotrophoblasts: 1664.9" "Cell type enhanced" "Detected in many" "LAMP5-LHX6 and Chandelier: 17.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 11.4" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Stomach - Mitotic cells (Stomach), Testis - Late spermatids" "Low region specificity" "Detected in all" "HPA062583, HPA073663" Enhanced Supported Nucleoplasm,Nucleoli NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." 9 Nucleoplasm Nucleoli "HPA062583: , HPA073663: " "unprognostic (1.23e-3)" "unprognostic (4.69e-3)" "unprognostic (1.33e-1)" "unprognostic (4.35e-2)" "unprognostic (2.00e-1)" "unprognostic (6.68e-2)" "unprognostic (2.89e-1)" "unprognostic (9.53e-3)" "unprognostic (1.39e-3)" "unprognostic (3.22e-1)" "unprognostic (5.77e-3)" "unprognostic (4.33e-2)" "unprognostic (2.22e-1)" "unprognostic (2.80e-3)" "unprognostic (5.22e-2)" "unprognostic (5.38e-2)" "unprognostic (8.45e-2)" "unprognostic (5.38e-2)" "unprognostic (4.47e-1)" "potential prognostic favorable (8.98e-4)" "unprognostic (3.49e-2)" "unprognostic (2.67e-2)" "unprognostic (1.08e-1)" "unprognostic (3.27e-2)" "unprognostic (2.09e-2)" "unprognostic (4.02e-1)" "unprognostic (1.35e-1)" "unprognostic (7.80e-2)" "unprognostic (7.34e-2)" "unprognostic (2.29e-1)" "unprognostic (7.42e-2)" HMGB4 FLJ40388 ENSG00000176256 "High mobility group box 4" Q8WW32 1 33860475-33864791 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1114 "testis: 556.6" "Group enriched" "Detected in some" 7 "Early spermatids: 13375.2;Late spermatids: 28225.0" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA035699 Enhanced NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 14: Neurons - Synaptic function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 2 "HPA035699: " HMGCL HL ENSG00000117305 "3-hydroxy-3-methylglutaryl-CoA lyase" P35914 1 23801885-23838620 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" Lyase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 321.5" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 125.0;Hepatocytes: 194.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Stomach - Gastric mucous cells, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004727 Enhanced NA NA 40000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 37: Non-specific - mRNA processing" "Cluster 97: Non-specific - Cellular respiration" 11 "HPA004727: " "unprognostic (2.49e-1)" "unprognostic (2.31e-1)" "unprognostic (5.91e-2)" "unprognostic (9.92e-2)" "unprognostic (7.45e-3)" "unprognostic (1.07e-1)" "unprognostic (3.51e-3)" "unprognostic (2.83e-2)" "unprognostic (4.07e-1)" "unprognostic (2.13e-1)" "validated prognostic favorable (3.20e-6)" "validated prognostic favorable (7.20e-4)" "potential prognostic favorable (5.81e-9)" "unprognostic (1.58e-1)" "unprognostic (4.88e-2)" "unprognostic (1.41e-1)" "unprognostic (2.61e-1)" "unprognostic (4.42e-2)" "unprognostic (1.33e-2)" "unprognostic (9.83e-2)" "unprognostic (1.19e-1)" "unprognostic (1.58e-1)" "unprognostic (5.75e-2)" "unprognostic (9.93e-2)" "unprognostic (1.54e-1)" "unprognostic (2.24e-2)" "unprognostic (1.14e-1)" "unprognostic (3.08e-1)" "unprognostic (8.67e-2)" "unprognostic (1.69e-1)" "unprognostic (8.09e-3)" HMGCLL1 "bA418P12.1, DKFZP434G1411" ENSG00000146151 "3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1" Q8TB92 6 55434373-55579197 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 9.1" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 138.3;Astrocytes: 96.3;Bergmann glia: 169.0;Brain excitatory neurons: 120.5;Brain inhibitory neurons: 128.3;Corticotrophs: 113.7;Fibro-adipogenic progenitors: 148.4;Lactotrophs: 172.6;Other brain neurons: 127.1;Pancreatic islet cells: 180.1;Pituitary stem cells: 361.9;Retinal amacrine cells: 89.7;Retinal bipolar cells: 81.7;Sertoli cells: 117.0;Somatotrophs: 77.4;Thyrotrophs: 182.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 1.8" "Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" "unprognostic (3.81e-3)" "unprognostic (1.36e-1)" "unprognostic (4.49e-2)" "unprognostic (9.86e-2)" "unprognostic (2.84e-1)" "unprognostic (6.32e-3)" HMGCR ENSG00000113161 "3-hydroxy-3-methylglutaryl-CoA reductase" P04035 5 75336329-75364001 "Enzymes, Essential proteins, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Disease variant, FDA approved drug targets, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 98.8" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 197.5;Endometrial luminal cells: 467.8;Epididymal principal cells: 260.5;Retinal ganglion cells: 197.0;Suprabasal keratinocytes: 176.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Kidney - Macrophages, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary gland basal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008338, CAB016797, CAB078688" Supported NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 76: Non-specific - Metabolism" "Cluster 24: Neurons - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 10 "CAB016797: , CAB078688: , HPA008338: " "unprognostic (6.96e-2)" "unprognostic (1.20e-2)" "unprognostic (3.41e-2)" "potential prognostic unfavorable (3.95e-6)" "unprognostic (4.24e-3)" "unprognostic (6.25e-3)" "unprognostic (6.61e-2)" "unprognostic (1.00e-2)" "unprognostic (1.35e-1)" "unprognostic (5.88e-3)" "potential prognostic favorable (1.41e-4)" "unprognostic (9.61e-3)" "unprognostic (6.95e-2)" "unprognostic (5.18e-2)" "unprognostic (1.88e-2)" "unprognostic (3.45e-2)" "unprognostic (2.43e-2)" "unprognostic (8.44e-2)" "unprognostic (2.29e-2)" "unprognostic (6.90e-2)" "unprognostic (1.70e-2)" "unprognostic (3.49e-1)" "unprognostic (1.70e-1)" "unprognostic (5.95e-2)" "unprognostic (2.29e-2)" "unprognostic (1.43e-2)" "unprognostic (7.41e-2)" "unprognostic (8.04e-2)" "unprognostic (2.26e-2)" "unprognostic (1.06e-2)" "unprognostic (3.02e-1)" HMGCS1 HMGCS ENSG00000112972 "3-hydroxy-3-methylglutaryl-CoA synthase 1" Q01581 5 43287470-43313512 "Enzymes, Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 364.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 590.3;Breast lactating cells: 390.4;Colonocytes: 539.3;Epididymal principal cells: 1140.0;Esophageal apical cells: 526.1;Esophageal suprabasal cells: 633.0;Retinal ganglion cells: 498.3;Suprabasal keratinocytes: 484.9;Urothelial cells: 659.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary gland basal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032907, HPA036913, HPA036914" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" No No 660000 "Cluster 29: Non-specific - Unknown function" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 49: Hindbrain - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 15 "Nucleoplasm, Cytosol" "Plasma membrane" "CAB032907: , HPA036913: , HPA036914: " "unprognostic (3.64e-1)" "unprognostic (1.28e-1)" "unprognostic (5.13e-2)" "unprognostic (9.33e-3)" "unprognostic (5.20e-2)" "unprognostic (1.14e-1)" "unprognostic (5.08e-2)" "unprognostic (7.53e-2)" "unprognostic (2.88e-2)" "unprognostic (9.11e-3)" "potential prognostic favorable (1.29e-6)" "unprognostic (4.52e-2)" "unprognostic (9.29e-2)" "unprognostic (5.59e-2)" "unprognostic (9.38e-2)" "unprognostic (3.51e-2)" "unprognostic (5.75e-2)" "unprognostic (2.01e-1)" "unprognostic (2.28e-3)" "unprognostic (1.59e-1)" "unprognostic (1.10e-1)" "unprognostic (6.91e-3)" "unprognostic (2.87e-3)" "unprognostic (9.60e-2)" "unprognostic (5.34e-2)" "unprognostic (6.27e-2)" "unprognostic (2.35e-2)" "unprognostic (3.50e-1)" "unprognostic (2.16e-1)" "unprognostic (4.79e-2)" "unprognostic (8.83e-2)" HMGCS2 ENSG00000134240 "3-hydroxy-3-methylglutaryl-CoA synthase 2" P54868 1 119748002-119768905 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "liver: 2275.9" "Cell type enhanced" "Detected in many" "Colonocytes: 497.2;Enteric stem cells: 407.2;Enteric transient amplifying cells: 322.5;Gastric chief cells: 196.6;Goblet cells: 275.6;Hepatocytes: 1287.8;Mucous neck cells: 242.3;Renal connecting tubule cells: 147.2;Retinal pigment epithelial cells: 285.6" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 667.0" "Region enriched" "Detected in single" 43 "choroid plexus: 11.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 41.6;colorectal cancer: 63.1;prostate cancer: 43.9" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA027423, HPA027442, CAB032906" Enhanced Approved Mitochondria NA NA 1800000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 36: Choroid plexus - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" Mitochondria "CAB032906: , HPA027423: , HPA027442: " "unprognostic (1.10e-1)" "unprognostic (2.02e-1)" "unprognostic (2.54e-1)" "unprognostic (1.86e-1)" "unprognostic (1.43e-2)" "unprognostic (9.02e-2)" "unprognostic (4.04e-3)" "potential prognostic favorable (2.03e-7)" "unprognostic (1.84e-3)" "unprognostic (3.32e-1)" "potential prognostic favorable (1.15e-5)" "unprognostic (9.32e-3)" "unprognostic (1.14e-3)" "unprognostic (1.92e-2)" "unprognostic (4.78e-2)" "unprognostic (7.58e-3)" "unprognostic (1.38e-3)" "unprognostic (1.68e-1)" "unprognostic (3.90e-2)" "unprognostic (1.93e-1)" "unprognostic (2.61e-1)" "unprognostic (1.07e-2)" "unprognostic (3.90e-2)" "unprognostic (1.78e-1)" "unprognostic (1.60e-1)" HMGN1 "FLJ27265, FLJ31471, HMG14, MGC104230, MGC117425" ENSG00000205581 "High mobility group nucleosome binding domain 1" P05114 21 39342315-39349647 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 1110.7;Megakaryocytes: 2039.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012260, HPA048694" Supported Supported Nucleoplasm NA NA 180000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 39: Astrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 27: Non-specific - Cell proliferation" 18 Nucleoplasm "CAB012260: , HPA048694: " "unprognostic (1.57e-1)" "unprognostic (6.99e-2)" "unprognostic (6.05e-2)" "unprognostic (5.94e-2)" "unprognostic (2.85e-1)" "unprognostic (8.89e-3)" "unprognostic (4.76e-2)" "unprognostic (1.25e-2)" "unprognostic (1.18e-2)" "potential prognostic unfavorable (4.53e-5)" "unprognostic (2.85e-2)" "unprognostic (4.50e-1)" "unprognostic (4.50e-2)" "potential prognostic unfavorable (2.23e-5)" "unprognostic (1.68e-2)" "potential prognostic unfavorable (3.26e-4)" "unprognostic (9.93e-3)" "unprognostic (5.92e-2)" "unprognostic (4.65e-1)" "unprognostic (1.62e-1)" "unprognostic (2.51e-1)" "unprognostic (1.14e-2)" "unprognostic (1.95e-1)" "unprognostic (4.48e-2)" "unprognostic (8.99e-2)" "unprognostic (2.59e-1)" "unprognostic (3.72e-2)" "unprognostic (1.75e-1)" "unprognostic (6.16e-2)" "unprognostic (2.67e-1)" "potential prognostic favorable (1.30e-4)" HMGN2 HMG17 ENSG00000198830 "High mobility group nucleosomal binding domain 2" P05204 1 26472440-26476642 "Essential proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Megakaryocyte progenitors: 245.1;Monocyte progenitors: 309.6;Neutrophil progenitors: 258.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "CAB018371, HPA077364" Supported Supported Nucleoplasm,Nucleoli NA NA 3200000 "Cluster 29: Non-specific - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 27: Non-specific - Cell proliferation" 37 Nucleoplasm Nucleoli "CAB018371: , HPA077364: " "unprognostic (2.37e-2)" "unprognostic (2.27e-1)" "unprognostic (1.58e-2)" "potential prognostic favorable (3.47e-5)" "unprognostic (2.47e-2)" "unprognostic (1.65e-1)" "unprognostic (2.87e-1)" "unprognostic (9.20e-3)" "unprognostic (2.71e-1)" "unprognostic (1.20e-2)" "potential prognostic favorable (3.08e-5)" "unprognostic (3.65e-2)" "unprognostic (3.83e-2)" "validated prognostic unfavorable (6.94e-5)" "validated prognostic unfavorable (7.37e-5)" "unprognostic (3.57e-2)" "unprognostic (6.82e-2)" "unprognostic (2.96e-2)" "unprognostic (1.31e-1)" "unprognostic (5.96e-2)" "unprognostic (1.54e-1)" "unprognostic (4.93e-2)" "unprognostic (8.25e-2)" "unprognostic (2.11e-1)" "unprognostic (1.10e-1)" "unprognostic (3.03e-1)" "unprognostic (1.53e-1)" "unprognostic (1.32e-1)" "unprognostic (1.30e-1)" "unprognostic (9.78e-2)" "unprognostic (7.82e-2)" HMGN3 TRIP7 ENSG00000118418 "High mobility group nucleosomal binding domain 3" Q15651 6 79201245-79234689 "Predicted intracellular proteins" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 1176.7;Extravillous trophoblasts: 1179.2;Fallopian tube ciliated cells: 1219.0;Migrating cytotrophoblasts: 882.2;Respiratory ciliated cells: 1038.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018370, HPA027971, HPA063572" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 4 Nucleoplasm Cytosol "CAB018370: , HPA027971: , HPA063572: " "unprognostic (2.48e-1)" "unprognostic (1.06e-1)" "unprognostic (8.38e-2)" "unprognostic (2.29e-2)" "unprognostic (1.95e-1)" "unprognostic (2.85e-1)" "unprognostic (2.24e-1)" "unprognostic (1.14e-1)" "unprognostic (6.61e-2)" "unprognostic (4.50e-2)" "potential prognostic unfavorable (1.57e-4)" "unprognostic (8.29e-2)" "unprognostic (1.11e-1)" "unprognostic (2.67e-2)" "unprognostic (3.61e-2)" "unprognostic (2.07e-2)" "unprognostic (7.85e-2)" "unprognostic (9.24e-3)" "unprognostic (1.34e-1)" "unprognostic (1.26e-3)" "unprognostic (4.15e-1)" "unprognostic (1.65e-3)" "unprognostic (1.06e-1)" "unprognostic (5.95e-2)" "unprognostic (3.52e-1)" "unprognostic (1.27e-1)" "unprognostic (3.41e-2)" "unprognostic (8.21e-3)" "unprognostic (3.49e-2)" "unprognostic (1.24e-1)" "unprognostic (2.83e-1)" HMGN4 "HMG17L3, NHC" ENSG00000182952 "High mobility group nucleosomal binding domain 4" O00479 6 26538366-26546933 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 153.8;Megakaryocytes: 142.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA077364 Approved Nucleoplasm,Nucleoli NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 28: Non-specific - Nuclear processes" "Cluster 67: Plasma cells - Plasma cell differentiation" 62 Nucleoplasm Nucleoli "HPA077364: " "unprognostic (1.97e-1)" "unprognostic (2.76e-1)" "unprognostic (6.57e-2)" "unprognostic (2.90e-2)" "unprognostic (1.12e-1)" "unprognostic (2.09e-1)" "unprognostic (1.22e-1)" "unprognostic (2.30e-1)" "unprognostic (8.89e-2)" "unprognostic (8.32e-2)" "potential prognostic favorable (3.93e-5)" "unprognostic (2.73e-3)" "unprognostic (7.86e-2)" "unprognostic (2.43e-3)" "potential prognostic unfavorable (5.92e-4)" "unprognostic (1.69e-1)" "unprognostic (4.17e-1)" "unprognostic (3.21e-1)" "unprognostic (6.95e-2)" "unprognostic (1.57e-1)" "unprognostic (1.37e-1)" "unprognostic (3.62e-3)" "unprognostic (1.11e-1)" "unprognostic (2.68e-1)" "unprognostic (2.00e-2)" "unprognostic (1.09e-1)" "unprognostic (2.17e-1)" "unprognostic (1.71e-1)" "unprognostic (2.14e-1)" "unprognostic (1.26e-1)" "unprognostic (2.44e-1)" HMGN5 NSBP1 ENSG00000198157 "High mobility group nucleosome binding domain 5" P82970 X 81113699-81201913 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 100.2" "Cell type enhanced" "Detected in many" "Epididymal efferent duct ciliated cells: 167.5;Epididymal principal cells: 213.7;Erythrocyte progenitors: 156.5;Sertoli cells: 409.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "HPA000511, HPA076238" Approved Supported Nucleoplasm,Mitochondria NA NA 17000 "Cluster 24: Non-specific - Transcription" "Cluster 67: Testis - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 117 Nucleoplasm Mitochondria "HPA000511: , HPA076238: " "unprognostic (1.35e-3)" "unprognostic (4.34e-3)" "unprognostic (8.16e-2)" "unprognostic (1.04e-1)" "unprognostic (1.85e-1)" "unprognostic (1.08e-1)" "unprognostic (7.70e-2)" "unprognostic (1.35e-1)" "unprognostic (9.83e-2)" "unprognostic (4.89e-2)" "unprognostic (2.90e-3)" "unprognostic (8.77e-2)" "unprognostic (4.20e-1)" "unprognostic (6.76e-2)" "unprognostic (2.40e-3)" "unprognostic (9.55e-2)" "unprognostic (1.23e-1)" "unprognostic (3.65e-1)" "unprognostic (8.99e-2)" "unprognostic (1.41e-2)" "unprognostic (2.10e-1)" "unprognostic (4.27e-2)" "unprognostic (1.16e-2)" "unprognostic (8.13e-2)" "unprognostic (3.60e-3)" "unprognostic (1.26e-2)" "unprognostic (2.14e-2)" "unprognostic (2.20e-2)" "unprognostic (1.01e-1)" "unprognostic (2.99e-2)" "unprognostic (1.42e-1)" HMGXB3 "HMGX3, KIAA0194, SMF" ENSG00000113716 "HMG-box containing 3" Q12766 5 150000046-150053142 "Plasma proteins, Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "parathyroid gland: 110.1" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005967 Approved Nucleoli NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 36: Choroid plexus - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 7: Non-specific - Transcription" Nucleoli "HPA005967: " "unprognostic (7.56e-2)" "unprognostic (2.80e-2)" "unprognostic (2.38e-1)" "unprognostic (5.50e-2)" "unprognostic (1.81e-1)" "unprognostic (3.04e-1)" "unprognostic (2.84e-1)" "unprognostic (3.95e-1)" "unprognostic (2.09e-2)" "unprognostic (4.00e-3)" "unprognostic (8.06e-2)" "unprognostic (1.14e-1)" "unprognostic (5.02e-2)" "potential prognostic unfavorable (2.30e-4)" "unprognostic (1.02e-1)" "unprognostic (1.01e-1)" "unprognostic (1.21e-1)" "unprognostic (3.17e-2)" "unprognostic (3.14e-1)" "unprognostic (3.68e-2)" "unprognostic (2.80e-3)" "unprognostic (2.94e-1)" "unprognostic (1.40e-3)" "unprognostic (2.92e-1)" "unprognostic (7.66e-2)" "unprognostic (4.75e-2)" "unprognostic (2.67e-1)" "unprognostic (4.16e-1)" "unprognostic (2.93e-1)" "unprognostic (3.41e-2)" "unprognostic (3.24e-2)" HMGXB4 "HMG2L1, P53N, THC211630" ENSG00000100281 "HMG-box containing 4" Q9UGU5 22 35257452-35295807 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Wnt signaling pathway" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000725, HPA076681" Approved Approved Nucleoplasm NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 27: Non-specific - Cell proliferation" 26 Nucleoplasm "HPA000725: , HPA076681: " "unprognostic (1.23e-2)" "unprognostic (3.31e-1)" "unprognostic (1.38e-2)" "unprognostic (7.55e-2)" "unprognostic (1.27e-2)" "unprognostic (1.98e-2)" "unprognostic (6.33e-2)" "unprognostic (1.22e-1)" "unprognostic (2.46e-1)" "unprognostic (3.31e-3)" "unprognostic (1.13e-2)" "unprognostic (3.17e-2)" "unprognostic (1.17e-1)" "unprognostic (1.08e-2)" "unprognostic (6.94e-2)" "unprognostic (4.12e-2)" "potential prognostic unfavorable (5.32e-4)" "unprognostic (1.36e-1)" "unprognostic (7.59e-3)" "unprognostic (5.83e-2)" "unprognostic (2.56e-3)" "unprognostic (5.56e-3)" "potential prognostic unfavorable (7.55e-5)" "unprognostic (2.04e-1)" "potential prognostic favorable (9.27e-6)" "unprognostic (7.34e-2)" "unprognostic (2.12e-2)" "unprognostic (2.05e-1)" "unprognostic (1.26e-1)" "unprognostic (4.65e-2)" "unprognostic (3.13e-1)" HMHB1 "HB-1, HB-1Y" ENSG00000158497 "Histocompatibility minor HB-1" O97980 5 143812161-143820716 "Predicted intracellular proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 2.2;testis: 1.3" "Cell type enriched" "Detected in single" 6 "Late primary spermatocytes: 4.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 25 "plasmacytoid DC: 20.1" "Lineage enriched" "Detected in single" 25 "dendritic cells: 20.1" "Group enriched" "Detected in some" 28 "Leukemia: 7.9;lymphoma: 2.8" NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 35: RS4;11 - Unknown function" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" HMMR "CD168, RHAMM" ENSG00000072571 "Hyaluronan mediated motility receptor" O75330 5 163460203-163491941 "CD markers, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.4;lymphoid tissue: 25.4;testis: 25.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 51.0;Differentiating spermatogonia: 46.8;Early primary spermatocytes: 47.6;Early spermatids: 72.2;Enteric transient amplifying cells: 64.6;Erythrocyte progenitors: 127.5;Extravillous trophoblasts: 65.0;Late primary spermatocytes: 171.3;Late spermatids: 96.8;Megakaryocyte progenitors: 115.9;Migrating cytotrophoblasts: 57.5;Monocyte progenitors: 155.5" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "T-reg: 1.5" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB002433, HPA040025, HPA043926, HPA061524" Enhanced Enhanced Microtubules,Centrosome,Cytosol Yes Yes "Cluster 13: Non-specific - Mitochondria" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 30: White matter - Myelination" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Non-specific - Cell proliferation" 27 Microtubules "Centrosome, Cytosol" "CAB002433: , HPA040025: , HPA043926: , HPA061524: " "unprognostic (3.14e-2)" "unprognostic (3.10e-2)" "unprognostic (6.94e-3)" "unprognostic (6.23e-2)" "unprognostic (1.54e-3)" "unprognostic (4.04e-1)" "unprognostic (1.12e-1)" "unprognostic (6.62e-2)" "unprognostic (2.21e-2)" "potential prognostic unfavorable (1.83e-4)" "validated prognostic unfavorable (6.62e-6)" "validated prognostic unfavorable (1.22e-7)" "potential prognostic unfavorable (3.18e-7)" "validated prognostic unfavorable (4.04e-8)" "validated prognostic unfavorable (2.90e-10)" "validated prognostic unfavorable (8.47e-7)" "validated prognostic unfavorable (3.79e-4)" "unprognostic (6.08e-2)" "unprognostic (2.15e-1)" "unprognostic (2.23e-1)" "unprognostic (2.10e-1)" "validated prognostic unfavorable (6.82e-4)" "validated prognostic unfavorable (9.43e-4)" "unprognostic (3.38e-1)" "unprognostic (2.42e-2)" "unprognostic (1.77e-2)" "unprognostic (1.42e-1)" "unprognostic (5.82e-2)" "unprognostic (1.52e-1)" "unprognostic (4.72e-2)" HMOX1 "bK286B10, HO-1" ENSG00000100292 "Heme oxygenase 1" P09601 22 35380361-35394214 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Host-virus interaction" Oxidoreductase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "lymphoid tissue: 740.2" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 492.0;Extravillous trophoblasts: 398.8;Hofbauer cells: 717.7;Kupffer cells: 2741.6;Macrophages: 565.0;monocytes: 376.3;Ocular epithelial cells: 250.3;Syncytiotrophoblasts: 847.0" "Group enriched" "Detected in many" 15 "central nervous system macrophage: 56.5;leukocyte: 30.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 98.9;intermediate monocyte: 239.0;non-classical monocyte: 331.0" "Lineage enriched" "Detected in all" 7 "monocytes: 331.0" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Proximal tubular cells, Prostate - Macrophages, Skin - Keratinocyte (granular), Spleen - Macrophages, Stomach - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000635, CAB017444" Enhanced Uncertain "Golgi apparatus,Plasma membrane" NA NA 58000 "Cluster 40: Monocytes - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 7: Liver cancer - Metabolism" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 45 "Golgi apparatus, Plasma membrane" "CAB017444: , HPA000635: " "unprognostic (2.99e-1)" "unprognostic (8.74e-2)" "unprognostic (1.02e-1)" "unprognostic (1.45e-1)" "unprognostic (8.62e-2)" "unprognostic (3.35e-1)" "unprognostic (2.88e-2)" "unprognostic (1.58e-1)" "unprognostic (2.48e-2)" "unprognostic (4.48e-2)" "potential prognostic favorable (1.81e-4)" "unprognostic (2.20e-2)" "unprognostic (1.71e-1)" "potential prognostic unfavorable (2.50e-4)" "unprognostic (9.81e-2)" "unprognostic (5.37e-2)" "unprognostic (1.66e-3)" "unprognostic (2.02e-1)" "unprognostic (4.60e-2)" "unprognostic (1.12e-1)" "unprognostic (8.97e-2)" "unprognostic (1.88e-1)" "unprognostic (4.19e-2)" "unprognostic (3.08e-1)" "unprognostic (1.27e-2)" "unprognostic (6.84e-2)" "unprognostic (2.69e-1)" "unprognostic (9.98e-2)" "unprognostic (5.60e-2)" "unprognostic (1.27e-1)" "unprognostic (1.75e-1)" HMOX2 HO-2 ENSG00000103415 "Heme oxygenase 2" P30519 16 4474690-4510347 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Late spermatids: 2469.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025464, HPA040611" Supported Approved Vesicles,Cytosol NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 35: Non-specific - Mixed function" "Cluster 45: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 92 "Vesicles, Cytosol" "CAB025464: , HPA040611: " "unprognostic (2.20e-2)" "unprognostic (2.97e-3)" "unprognostic (2.12e-2)" "unprognostic (4.64e-2)" "unprognostic (3.12e-2)" "unprognostic (2.33e-1)" "unprognostic (7.62e-2)" "unprognostic (2.58e-3)" "unprognostic (2.20e-1)" "unprognostic (2.82e-1)" "potential prognostic favorable (8.87e-7)" "unprognostic (3.54e-2)" "unprognostic (7.17e-3)" "unprognostic (6.00e-2)" "unprognostic (1.98e-2)" "unprognostic (1.57e-1)" "unprognostic (3.13e-2)" "unprognostic (2.68e-1)" "unprognostic (4.25e-1)" "unprognostic (2.06e-1)" "unprognostic (9.56e-2)" "unprognostic (7.37e-3)" "unprognostic (3.54e-1)" "unprognostic (2.62e-1)" "unprognostic (2.28e-1)" "unprognostic (8.92e-2)" "unprognostic (3.12e-2)" "unprognostic (2.33e-1)" "unprognostic (2.85e-1)" "unprognostic (2.42e-1)" "unprognostic (1.70e-3)" HMSD "ACC-6, ACC6, C18orf53" ENSG00000221887 "Histocompatibility minor serpin domain containing" "A8MTL9, P0C7T4" 18 63949301-63981774 "Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "brain: 30.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 15.3;Early primary spermatocytes: 8.0;Epicardial cells: 38.7;Esophageal basal cells: 8.9;Oligodendrocytes: 9.4;pDCs: 12.4;Respiratory deuterosomal cells: 6.2;Retinal horizontal cells: 6.0;Undifferentiated spermatogonia: 8.3" "Cell type enriched" "Detected in some" 5 "oligodendrocyte: 15.8" "Cancer enhanced" "Detected in some" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 4.9" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 19 "plasmacytoid DC: 1.8" "Lineage enriched" "Detected in single" 19 "dendritic cells: 1.8" "Cancer enhanced" "Detected in many" "lymphoma: 7.3" "Adipose visceral - Mesothelial cells, Liver - Hepatic stellate cells" "Low region specificity" "Detected in all" "Secreted to blood" "Enzyme inhibitor" NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 82: Dendritic cells - Antigen presentation" "unprognostic (3.30e-1)" "unprognostic (3.86e-3)" "unprognostic (2.66e-1)" "unprognostic (2.46e-2)" "unprognostic (1.51e-2)" "unprognostic (2.58e-2)" "unprognostic (5.35e-2)" "unprognostic (1.33e-2)" "unprognostic (7.25e-2)" HMX1 "H6, NKX5-3" ENSG00000215612 "H6 family homeobox 1" Q9NP08 4 8846076-8871839 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Cataract, Microphthalmia" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 1.9;retina: 2.2;testis: 1.2" "Cell type enhanced" "Detected in some" "Astrocytes: 1.1;Müller glia: 5.4;Oligodendrocyte progenitor cells: 18.6;Oligodendrocytes: 4.5;Retinal horizontal cells: 2.0" "Group enriched" "Detected in some" 8 "committed oligodendrocyte precursor: 14.7;oligodendrocyte precursor cell: 20.7" "Cancer enhanced" "Detected in single" "Glioblastoma Multiforme (TCGA): 1.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Neuroblastoma: 7.5" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" "unprognostic (5.87e-2)" "potential prognostic favorable (1.12e-5)" HMX2 NKX5-2 ENSG00000188816 "H6 family homeobox 2" A2RU54 10 123148136-123150672 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "brain: 1.7;kidney: 1.8" "Cell type enriched" "Detected in some" 5 "Tuft cells: 34.6" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 1.6" "Region enhanced" "Detected in some" "midbrain: 4.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 3.3" "Colon - Colon enteroendocrine cells, Kidney - Intercalated cells" "Not detected" "Not detected" "Region enhanced" "Detected in single" "hypothalamus: 2.4" "CAB013268, CAB022752" Approved NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 24: Non-specific - Unknown function" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 2 "CAB013268: , CAB022752: " "potential prognostic favorable (1.65e-4)" HMX3 NKX5-1 ENSG00000188620 "H6 family homeobox 3" A6NHT5 10 123135970-123139423 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 5 "brain: 4.5" "Cell type enriched" "Detected in some" 6 "Tuft cells: 34.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in some" "cervical cancer: 4.0;Leukemia: 5.8" "Colon - Colon enteroendocrine cells, Pituitary gland - Lactotropes" "Region enriched" "Detected in single" 4 "hypothalamus: 1.1" "Group enriched" "Detected in some" 5 "basal ganglia: 2.2;hypothalamus: 6.7" HPA069659 Approved "Nucleoplasm,Centriolar satellite" Yes No "Cluster 36: Brain & Liver - Signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 24: Non-specific - Unknown function" "Cluster 95: Tuft cells - Chemosensory signaling" 1 Nucleoplasm "Centriolar satellite" "HPA069659: " "unprognostic (6.17e-2)" "unprognostic (5.79e-2)" "unprognostic (1.39e-1)" "unprognostic (4.93e-2)" HNF1A "HNF1, HNF1alpha, LFB1, MODY3, TCF1" ENSG00000135100 "HNF1 homeobox A" 12 120978543-121002512 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "intestine: 13.2;kidney: 8.1;liver: 9.7;pancreas: 5.1;stomach 1: 3.6" "Cell type enhanced" "Detected in some" "Colonocytes: 15.0;Enteric stem cells: 11.0;Enteric transient amplifying cells: 14.2;Enterocytes: 37.0;Epididymal efferent duct absorptive cells: 14.2;Goblet cells: 13.2;Hepatocytes: 25.8;Neuroendocrine cells: 10.5;Oocytes: 32.2;Pancreatic acinar cells: 9.3;Paneth cells: 11.6;Proximal tubule cells: 66.4" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 14.9;Gastric cancer: 9.8;liver cancer: 18.1" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB010430, HPA035231" Enhanced Supported Nucleoplasm NA NA "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 88: Proximal tubular cells - Transmembrane transport" 13 Nucleoplasm "CAB010430: , HPA035231: " "unprognostic (2.38e-1)" "unprognostic (1.87e-1)" "unprognostic (1.16e-1)" "unprognostic (2.41e-1)" "unprognostic (1.89e-1)" "potential prognostic favorable (1.22e-6)" "unprognostic (1.72e-2)" "unprognostic (1.65e-2)" "unprognostic (2.27e-2)" "unprognostic (6.14e-2)" "unprognostic (6.04e-2)" "unprognostic (5.03e-3)" "unprognostic (1.08e-2)" "unprognostic (5.69e-2)" "unprognostic (3.39e-3)" "unprognostic (6.93e-2)" "unprognostic (4.49e-2)" "unprognostic (1.31e-1)" "unprognostic (8.31e-2)" HNF1B "HNF1beta, LFB3, MODY5, TCF2, VHNF1" ENSG00000275410 "HNF1 homeobox B" P35680 17 37686431-37745059 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 67.4;pancreas: 33.1" "Group enriched" "Detected in some" 7 "Distal convoluted tubule cells: 178.2;Loop of henle epithelial cells: 254.6;Papillary tip epithelial cells: 75.3;Proximal tubule cells: 132.2;Renal collecting duct intercalated cells: 195.6;Renal collecting duct principal cells: 170.1;Renal connecting tubule cells: 225.0" "Cell type enhanced" "Detected in single" "hippocampal CA4: 1.5" "Group enriched" "Detected in many" 5 "Kidney Renal Clear Cell Carcinoma (TCGA): 46.3;Kidney Renal Papillary Cell Carcinoma (TCGA): 131.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 49.9" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Prostate - Prostate basal glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Region enhanced" "Detected in single" "hypothalamus: 2.0" "Low region specificity" "Detected in many" "HPA002083, CAB068192" Enhanced Supported Nucleoplasm,Vesicles NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 15: Kidney cancer - Membrane components" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 14 Nucleoplasm Vesicles "CAB068192: , HPA002083: " "unprognostic (1.17e-1)" "unprognostic (2.53e-1)" "unprognostic (3.25e-1)" "unprognostic (2.66e-1)" "unprognostic (1.71e-3)" "unprognostic (3.72e-2)" "unprognostic (3.10e-2)" "unprognostic (1.16e-3)" "unprognostic (6.94e-2)" "unprognostic (3.12e-1)" "unprognostic (2.57e-2)" "unprognostic (3.19e-1)" "unprognostic (2.48e-1)" "unprognostic (2.18e-2)" "unprognostic (3.28e-1)" "unprognostic (7.94e-2)" "unprognostic (7.91e-2)" "unprognostic (2.07e-1)" "unprognostic (3.53e-1)" "unprognostic (1.11e-1)" HNF4A "HNF4, MODY, MODY1, NR2A1, TCF14" ENSG00000101076 "Hepatocyte nuclear factor 4 alpha" P41235 20 44355699-44432845 "Disease related genes, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor, Repressor" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 96.1;kidney: 42.7;liver: 112.7" "Cell type enhanced" "Detected in some" "Colonocytes: 443.6;Enteric stem cells: 432.7;Enteric transient amplifying cells: 348.2;Enterocytes: 333.4;Foveolar cells: 210.3;Gastric progenitor cells: 182.0;Goblet cells: 235.7;Hepatocytes: 281.9;Neuroendocrine cells: 168.2;Paneth cells: 355.8;Proximal tubule cells: 216.9;Tuft cells: 196.0" "Cell type enriched" "Detected in some" 30 "choroid plexus epithelial cell: 43.2" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 117.4;Rectum Adenocarcinoma (TCGA): 129.2" "Region enriched" "Detected in all" 10 "choroid plexus: 32.2" "Immune cell enhanced" "Detected in single" "basophil: 1.8" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 4 "Bile duct cancer: 19.2;colorectal cancer: 57.4;Gastric cancer: 33.3;liver cancer: 41.4" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA004712, CAB019417" Enhanced Supported Nucleoplasm NA NA "Cluster 77: Intestine - Digestion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 38 Nucleoplasm "CAB019417: , HPA004712: " "unprognostic (1.77e-1)" "unprognostic (2.15e-1)" "unprognostic (2.31e-1)" "potential prognostic favorable (5.97e-7)" "unprognostic (1.61e-2)" "unprognostic (2.81e-2)" "unprognostic (4.61e-2)" "unprognostic (8.08e-2)" "unprognostic (1.52e-2)" "unprognostic (4.62e-2)" "unprognostic (1.68e-2)" "unprognostic (4.08e-3)" "unprognostic (2.41e-3)" "unprognostic (1.02e-2)" "unprognostic (1.40e-1)" "unprognostic (6.40e-3)" HNF4G NR2A2 ENSG00000164749 "Hepatocyte nuclear factor 4 gamma" Q14541 8 75407914-75566834 "Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "intestine: 108.0" "Cell type enhanced" "Detected in many" "Cholangiocytes: 210.7;Colonocytes: 272.8;Enteric stem cells: 253.4;Enteric transient amplifying cells: 264.9;Enterocytes: 771.5;Foveolar cells: 168.7;Goblet cells: 290.7;Neuroendocrine cells: 197.9;Pancreatic acinar cells: 190.9;Paneth cells: 375.1;Proximal tubule cells: 156.0;Tuft cells: 172.9" "Cell type enhanced" "Detected in many" "astrocyte: 79.3;Bergmann glia: 82.1;ependymal cell: 75.9;oligodendrocyte precursor cell: 42.8" "Cancer enhanced" "Detected in many" "Stomach Adenocarcinoma (TCGA): 17.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Gonadotropes, Prostate - Urothelial cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA005438, HPA010610" Enhanced Enhanced "Nucleoplasm,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 39: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 1: Enterocytes - Absorption and Digestion" 1 Nucleoplasm "Cytokinetic bridge, Mitotic spindle, Cytosol" "HPA005438: , HPA010610: " "unprognostic (2.61e-1)" "unprognostic (1.98e-1)" "unprognostic (8.94e-2)" "unprognostic (1.26e-1)" "unprognostic (3.70e-2)" "unprognostic (3.88e-2)" "potential prognostic unfavorable (7.30e-4)" "potential prognostic favorable (2.67e-8)" "unprognostic (2.79e-2)" "unprognostic (3.57e-2)" "unprognostic (1.17e-2)" "unprognostic (5.46e-2)" "unprognostic (3.31e-3)" "unprognostic (1.32e-3)" "unprognostic (4.74e-2)" "unprognostic (9.05e-3)" "unprognostic (1.60e-2)" "unprognostic (8.59e-2)" "unprognostic (8.27e-2)" "unprognostic (2.02e-2)" "unprognostic (5.36e-2)" "unprognostic (3.22e-2)" "unprognostic (2.42e-1)" "unprognostic (1.38e-1)" HNMT ENSG00000150540 "Histamine N-methyltransferase" P50135 2 137964020-138016364 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Methyltransferase, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 229.7" "Cell type enhanced" "Detected in many" "Hepatocytes: 241.4;Hofbauer cells: 460.2;Kupffer cells: 482.7" "Cell type enhanced" "Detected in all" "Bergmann glia: 168.6;central nervous system macrophage: 142.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 21 "classical monocyte: 111.1;intermediate monocyte: 89.9;myeloid DC: 68.3;non-classical monocyte: 52.5" "Group enriched" "Detected in many" 23 "dendritic cells: 68.3;monocytes: 111.1" "Cancer enhanced" "Detected in many" "testis cancer: 99.4" "Liver - Hepatocytes, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035480, HPA035481, HPA073754" Approved Approved Nucleoplasm,Centrosome,Cytosol NA NA 100000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 55: Non-specific - Transcription" "Cluster 18: Liver cancer - Metabolism" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" "Nucleoplasm, Cytosol" Centrosome "HPA035480: , HPA035481: , HPA073754: " "unprognostic (4.80e-2)" "unprognostic (1.58e-1)" "unprognostic (1.12e-1)" "unprognostic (2.35e-1)" "unprognostic (7.89e-2)" "unprognostic (1.24e-2)" "unprognostic (1.79e-1)" "unprognostic (5.53e-1)" "unprognostic (2.40e-1)" "unprognostic (5.11e-2)" "potential prognostic favorable (2.05e-10)" "unprognostic (1.39e-3)" "unprognostic (6.94e-2)" "unprognostic (1.60e-1)" "unprognostic (8.34e-3)" "unprognostic (6.14e-3)" "unprognostic (8.35e-2)" "unprognostic (3.13e-2)" "unprognostic (1.01e-1)" "unprognostic (1.27e-1)" "unprognostic (1.62e-1)" "potential prognostic unfavorable (5.07e-4)" "unprognostic (1.60e-1)" "unprognostic (2.97e-1)" "unprognostic (1.89e-2)" "unprognostic (1.48e-1)" "unprognostic (5.08e-3)" "unprognostic (1.65e-2)" "unprognostic (5.09e-2)" "unprognostic (1.84e-1)" "unprognostic (1.16e-1)" HNRNPA0 HNRPA0 ENSG00000177733 "Heterogeneous nuclear ribonucleoprotein A0" Q13151 5 137745651-137754363 "Plasma proteins, Predicted intracellular proteins" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 605.0;Migrating cytotrophoblasts: 472.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "HPA036569, HPA059404" Enhanced Enhanced Nucleoplasm No No 56000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 54: Non-specific - Ribosome" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 15: Non-specific - Protein processing" 90 Nucleoplasm "HPA036569: , HPA059404: " "unprognostic (1.21e-1)" "unprognostic (1.54e-1)" "unprognostic (9.61e-2)" "unprognostic (2.08e-2)" "unprognostic (1.66e-1)" "unprognostic (1.11e-1)" "unprognostic (1.54e-1)" "unprognostic (2.51e-1)" "unprognostic (2.87e-1)" "unprognostic (2.75e-1)" "validated prognostic favorable (1.47e-6)" "validated prognostic favorable (3.88e-4)" "unprognostic (1.51e-1)" "unprognostic (1.16e-3)" "unprognostic (1.02e-3)" "unprognostic (8.05e-3)" "unprognostic (7.63e-2)" "unprognostic (4.08e-1)" "unprognostic (1.93e-2)" "unprognostic (3.26e-1)" "unprognostic (5.67e-2)" "unprognostic (1.34e-2)" "unprognostic (3.69e-1)" "unprognostic (5.32e-2)" "unprognostic (7.86e-2)" "unprognostic (1.49e-1)" "unprognostic (8.58e-2)" "unprognostic (5.40e-1)" "unprognostic (1.77e-1)" "unprognostic (2.01e-2)" "unprognostic (2.23e-2)" HNRNPA1 "ALS20, hnRNP-A1, HNRPA1" ENSG00000135486 "Heterogeneous nuclear ribonucleoprotein A1" P09651 12 54280193-54287088 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing, mRNA transport, Transport" "Ribonucleoprotein, RNA-binding" "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 735.7;Megakaryocyte-Erythroid progenitors: 597.4;Migrating cytotrophoblasts: 630.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001609, HPA001666, HPA005812, HPA007185, CAB010894, HPA077520" Supported Enhanced Nucleoplasm NA NA 4600000 "Cluster 11: T-cells - Unknown function" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 270 Nucleoplasm "CAB010894: , HPA001609: , HPA001666: , HPA005812: , HPA007185: , HPA077520: " "unprognostic (3.26e-3)" "unprognostic (1.96e-2)" "unprognostic (3.17e-2)" "unprognostic (9.46e-3)" "unprognostic (1.00e-2)" "unprognostic (1.16e-1)" "unprognostic (5.29e-2)" "unprognostic (2.67e-2)" "unprognostic (1.90e-1)" "unprognostic (2.48e-1)" "potential prognostic favorable (3.11e-6)" "unprognostic (9.86e-3)" "potential prognostic unfavorable (1.04e-4)" "unprognostic (5.06e-3)" "unprognostic (1.97e-3)" "unprognostic (2.36e-2)" "potential prognostic unfavorable (8.58e-4)" "unprognostic (2.61e-2)" "unprognostic (1.54e-1)" "unprognostic (8.43e-2)" "unprognostic (2.31e-2)" "unprognostic (5.81e-3)" "unprognostic (2.29e-1)" "unprognostic (3.14e-1)" "unprognostic (7.81e-2)" "unprognostic (2.35e-1)" "unprognostic (4.00e-1)" "unprognostic (2.31e-1)" "unprognostic (2.41e-1)" "unprognostic (2.17e-1)" "unprognostic (6.47e-3)" HNRNPA1L2 LOC144983 ENSG00000139675 "Heterogeneous nuclear ribonucleoprotein A1 like 2" Q32P51 13 52642431-52643773 "Predicted intracellular proteins" "mRNA processing, mRNA splicing, mRNA transport, Transport" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 2.6;Loop of henle epithelial cells: 3.4;Papillary tip epithelial cells: 1.1;Podocytes: 2.1;Proximal tubule cells: 3.0;Renal collecting duct intercalated cells: 2.1;Renal collecting duct principal cells: 1.9;Renal connecting tubule cells: 2.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" HPA077520 Approved Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 16: Non-specific - Transcription" "Cluster 19: Non-specific - Unknown function" "Cluster 105: Non-specific - Mixed function" 9 Nucleoplasm "HPA077520: " "potential prognostic favorable (3.03e-4)" "unprognostic (2.66e-3)" "unprognostic (6.80e-2)" "unprognostic (2.10e-1)" "unprognostic (4.89e-2)" "unprognostic (9.99e-2)" "unprognostic (9.60e-2)" "unprognostic (3.17e-1)" "unprognostic (8.07e-2)" "unprognostic (1.26e-1)" "unprognostic (1.54e-1)" "unprognostic (8.38e-3)" "potential prognostic favorable (3.52e-4)" "unprognostic (3.23e-1)" "unprognostic (1.08e-1)" "unprognostic (3.35e-2)" "unprognostic (3.10e-2)" "unprognostic (2.37e-2)" "unprognostic (1.87e-1)" "unprognostic (5.96e-2)" "unprognostic (4.38e-2)" "unprognostic (5.47e-2)" "unprognostic (3.21e-2)" "unprognostic (1.44e-2)" "unprognostic (2.56e-2)" "unprognostic (1.07e-1)" "unprognostic (8.85e-2)" "unprognostic (3.17e-1)" "unprognostic (1.03e-1)" "unprognostic (9.37e-3)" "unprognostic (1.38e-1)" HNRNPA1L3 HNRNPA1P48 ENSG00000224578 "Heterogeneous nuclear ribonucleoprotein A1 like 3" A0A2R8Y4L2 16 51553436-51647132 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 69.5;Enteric stem cells: 64.2;Enteric transient amplifying cells: 60.2;Epididymal basal cells: 66.1;Extravillous trophoblasts: 104.0;Migrating cytotrophoblasts: 87.3;Syncytiotrophoblasts: 65.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA001666, HPA005812, HPA077520" Uncertain Supported Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 61: BICR 18 - Protein kinases" "Cluster 15: Non-specific - Protein processing" Nucleoplasm "HPA001666: , HPA005812: , HPA077520: " "unprognostic (7.07e-3)" "unprognostic (9.98e-2)" "unprognostic (2.82e-1)" HNRNPA2B1 HNRPA2B1 ENSG00000122566 "Heterogeneous nuclear ribonucleoprotein A2/B1" P22626 7 26171151-26201529 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing, mRNA transport, Transport" "Ribonucleoprotein, RNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001666, HPA005812, CAB012403, HPA065537" Supported Enhanced Nucleoplasm "Intracellular and membrane" Transport NA NA 5400000 "Cluster 30: Non-specific - DNA binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 56: Non-specific - Sensory perception" "Cluster 20: Non-specific - Transcription regulation" 169 Nucleoplasm "CAB012403: , HPA001666: , HPA005812: , HPA065537: " "unprognostic (4.06e-3)" "unprognostic (2.04e-1)" "unprognostic (1.17e-1)" "unprognostic (1.61e-1)" "unprognostic (2.88e-2)" "unprognostic (3.16e-1)" "unprognostic (6.24e-2)" "unprognostic (3.08e-1)" "unprognostic (1.44e-1)" "unprognostic (4.53e-1)" "potential prognostic unfavorable (1.01e-5)" "unprognostic (1.37e-1)" "unprognostic (1.02e-1)" "unprognostic (1.16e-3)" "unprognostic (2.66e-3)" "unprognostic (1.30e-1)" "unprognostic (1.63e-2)" "unprognostic (3.09e-2)" "unprognostic (8.48e-3)" "unprognostic (1.62e-1)" "unprognostic (3.90e-1)" "unprognostic (2.44e-1)" "unprognostic (1.02e-2)" "unprognostic (4.03e-2)" "unprognostic (2.40e-1)" "unprognostic (3.05e-1)" "unprognostic (2.18e-2)" "unprognostic (9.48e-2)" "unprognostic (1.63e-1)" "unprognostic (7.24e-2)" "unprognostic (4.41e-1)" HNRNPA3 HNRPA3 ENSG00000170144 "Heterogeneous nuclear ribonucleoprotein A3" P51991 2 177212694-177223959 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001666, HPA005812, HPA066381" Supported Enhanced Nucleoplasm NA NA 460000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 49: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 17: Non-specific - RNA processing" 113 Nucleoplasm "HPA001666: , HPA005812: , HPA066381: " "unprognostic (6.81e-2)" "unprognostic (1.71e-1)" "unprognostic (5.05e-1)" "unprognostic (5.91e-3)" "unprognostic (9.22e-2)" "unprognostic (1.97e-2)" "unprognostic (2.77e-2)" "unprognostic (2.13e-1)" "unprognostic (5.05e-2)" "unprognostic (1.85e-1)" "potential prognostic favorable (1.93e-4)" "unprognostic (3.65e-3)" "unprognostic (1.68e-3)" "validated prognostic unfavorable (2.89e-5)" "validated prognostic unfavorable (3.61e-4)" "unprognostic (4.59e-3)" "unprognostic (1.83e-2)" "unprognostic (5.89e-2)" "unprognostic (1.01e-3)" "unprognostic (1.46e-2)" "unprognostic (1.53e-1)" "potential prognostic unfavorable (4.82e-4)" "unprognostic (9.80e-3)" "unprognostic (5.23e-2)" "unprognostic (6.10e-2)" "unprognostic (2.25e-1)" "unprognostic (1.93e-1)" "unprognostic (5.69e-2)" "unprognostic (2.06e-1)" "unprognostic (2.01e-1)" "unprognostic (6.63e-2)" HNRNPAB "ABBP1, FLJ40338, HNRPAB" ENSG00000197451 "Heterogeneous nuclear ribonucleoprotein A/B" Q99729 5 178204533-178211163 "Plasma proteins, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 647.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046688 Approved Enhanced Nucleoplasm NA NA 330000 "Cluster 22: Eosinophils - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 17: Non-specific - RNA processing" 77 Nucleoplasm "HPA046688: " "unprognostic (9.25e-2)" "unprognostic (7.11e-2)" "unprognostic (1.92e-2)" "unprognostic (1.31e-1)" "unprognostic (1.25e-1)" "unprognostic (7.18e-2)" "unprognostic (1.06e-1)" "unprognostic (2.51e-1)" "unprognostic (2.35e-2)" "potential prognostic unfavorable (7.79e-5)" "unprognostic (4.05e-2)" "unprognostic (9.65e-2)" "potential prognostic unfavorable (9.40e-4)" "potential prognostic unfavorable (9.32e-4)" "unprognostic (2.11e-3)" "unprognostic (1.53e-3)" "unprognostic (8.94e-3)" "unprognostic (8.17e-2)" "unprognostic (3.26e-2)" "unprognostic (3.82e-3)" "unprognostic (6.34e-2)" "unprognostic (1.41e-2)" "unprognostic (3.18e-1)" "potential prognostic unfavorable (2.78e-4)" "unprognostic (4.58e-2)" "unprognostic (8.56e-2)" "unprognostic (1.81e-2)" "unprognostic (3.91e-2)" "unprognostic (3.10e-1)" "unprognostic (1.42e-1)" "unprognostic (3.90e-2)" HNRNPC HNRPC ENSG00000092199 "Heterogeneous nuclear ribonucleoprotein C" P07910 14 21209136-21269494 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 1730.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005223, HPA051075, CAB075755, CAB075756, HPA078646" Supported Enhanced Nucleoplasm NA NA 1200000 "Cluster 21: Neutrophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 241 Nucleoplasm "CAB005223: , CAB075755: , CAB075756: , HPA051075: , HPA078646: " "potential prognostic unfavorable (1.23e-4)" "unprognostic (1.00e-1)" "unprognostic (2.25e-2)" "unprognostic (2.51e-2)" "unprognostic (1.60e-2)" "unprognostic (3.62e-1)" "unprognostic (3.66e-3)" "unprognostic (4.51e-2)" "unprognostic (1.40e-3)" "unprognostic (1.76e-2)" "potential prognostic favorable (3.13e-4)" "unprognostic (5.51e-2)" "unprognostic (7.47e-3)" "potential prognostic unfavorable (5.19e-5)" "unprognostic (1.66e-2)" "validated prognostic unfavorable (1.08e-5)" "validated prognostic unfavorable (6.00e-4)" "unprognostic (3.82e-2)" "unprognostic (1.48e-1)" "unprognostic (6.83e-2)" "unprognostic (3.11e-1)" "unprognostic (2.47e-3)" "unprognostic (2.13e-1)" "unprognostic (6.50e-2)" "unprognostic (1.81e-1)" "unprognostic (1.68e-1)" "unprognostic (8.16e-2)" "unprognostic (2.83e-1)" "unprognostic (2.66e-1)" "unprognostic (4.06e-2)" "unprognostic (6.85e-2)" HNRNPCL1 HNRPCL1 ENSG00000179172 "Heterogeneous nuclear ribonucleoprotein C like 1" O60812 1 12847377-12848720 "Predicted intracellular proteins" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA078646 Approved Nucleoplasm NA NA 32 Nucleoplasm "HPA078646: " HNRNPCL2 HNRNPCP5 ENSG00000275774 "Heterogeneous nuclear ribonucleoprotein C like 2" B2RXH8 1 13115488-13116854 "Predicted intracellular proteins" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA078646 Approved Nucleoplasm NA NA "Cluster 53: Squamous epithelial cells - Keratinization" 17 Nucleoplasm "HPA078646: " HNRNPCL3 ENSG00000277058 "Heterogeneous nuclear ribonucleoprotein C like 3" B7ZW38 1 13060769-13062878 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA078646 Approved Nucleoplasm NA NA "Cluster 59: Leukemia - T-cell receptor" 1 Nucleoplasm "HPA078646: " HNRNPCL4 ENSG00000179412 "Heterogeneous nuclear ribonucleoprotein C like 4" P0DMR1 1 13163914-13165631 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA078646 Approved Nucleoplasm NA NA "Cluster 71: Lymphoma - Inflammatory response" Nucleoplasm "HPA078646: " HNRNPD "AUF1, HNRPD" ENSG00000138668 "Heterogeneous nuclear ribonucleoprotein D" Q14103 4 82352498-82374503 "Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "DNA-binding, Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004911 Supported Enhanced Nucleoplasm NA NA 860000 "Cluster 30: Non-specific - DNA binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 16: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 17: Non-specific - RNA processing" 178 Nucleoplasm "HPA004911: " "unprognostic (8.30e-3)" "unprognostic (8.78e-3)" "unprognostic (4.78e-1)" "unprognostic (1.15e-1)" "unprognostic (1.09e-1)" "unprognostic (8.13e-2)" "unprognostic (3.64e-2)" "unprognostic (1.40e-1)" "unprognostic (1.09e-1)" "unprognostic (1.65e-2)" "potential prognostic favorable (5.99e-4)" "unprognostic (3.20e-3)" "unprognostic (2.12e-1)" "potential prognostic unfavorable (2.91e-4)" "unprognostic (4.53e-2)" "unprognostic (1.69e-3)" "unprognostic (2.52e-3)" "unprognostic (1.14e-1)" "unprognostic (1.01e-2)" "unprognostic (2.44e-1)" "unprognostic (7.45e-2)" "unprognostic (9.01e-3)" "unprognostic (3.02e-2)" "unprognostic (3.22e-2)" "unprognostic (2.21e-2)" "unprognostic (3.51e-1)" "unprognostic (2.09e-1)" "unprognostic (2.24e-1)" "unprognostic (2.72e-1)" "unprognostic (2.55e-1)" "unprognostic (4.06e-2)" HNRNPDL "HNRPDL, JKTBP, laAUF1, LGMD1G" ENSG00000152795 "Heterogeneous nuclear ribonucleoprotein D like" O14979 4 82422565-82430462 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor, RNA-binding" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056820, HPA063147" Supported Enhanced Nucleoplasm NA NA 300000 "Cluster 14: Non-specific - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 20: Non-specific - Transcription regulation" 87 Nucleoplasm "HPA056820: , HPA063147: " "unprognostic (4.81e-2)" "unprognostic (6.81e-2)" "unprognostic (6.22e-2)" "unprognostic (1.47e-1)" "unprognostic (3.83e-1)" "unprognostic (1.56e-1)" "unprognostic (3.06e-3)" "unprognostic (2.76e-2)" "unprognostic (1.45e-1)" "unprognostic (1.08e-3)" "unprognostic (1.79e-2)" "unprognostic (2.22e-1)" "unprognostic (6.21e-3)" "unprognostic (6.25e-2)" "unprognostic (1.90e-2)" "unprognostic (6.53e-2)" "unprognostic (2.81e-2)" "unprognostic (4.11e-2)" "unprognostic (2.08e-2)" "unprognostic (1.01e-2)" "unprognostic (4.67e-2)" "unprognostic (9.68e-2)" "unprognostic (1.34e-2)" "unprognostic (4.00e-2)" "unprognostic (1.06e-1)" "unprognostic (1.80e-1)" "unprognostic (2.62e-2)" "unprognostic (2.21e-2)" "unprognostic (5.15e-2)" HNRNPF HNRPF ENSG00000169813 "Heterogeneous nuclear ribonucleoprotein F" P52597 10 43385617-43409186 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016884, HPA069667" Supported Enhanced Nucleoplasm NA Yes 620000 "Cluster 33: Non-specific - ATP binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 46: Brainstem - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 17: Non-specific - RNA processing" 106 Nucleoplasm "HPA016884: , HPA069667: " "unprognostic (1.77e-2)" "unprognostic (4.56e-2)" "unprognostic (5.89e-2)" "unprognostic (7.19e-2)" "unprognostic (1.72e-1)" "unprognostic (3.74e-2)" "unprognostic (1.11e-1)" "unprognostic (4.52e-2)" "unprognostic (7.61e-2)" "unprognostic (5.88e-2)" "potential prognostic favorable (2.22e-5)" "unprognostic (3.28e-2)" "unprognostic (4.49e-2)" "potential prognostic unfavorable (8.62e-4)" "unprognostic (9.77e-2)" "unprognostic (2.27e-3)" "potential prognostic unfavorable (1.59e-4)" "unprognostic (1.44e-1)" "unprognostic (2.56e-1)" "unprognostic (2.03e-1)" "unprognostic (4.03e-1)" "unprognostic (1.52e-3)" "unprognostic (7.90e-2)" "unprognostic (1.24e-2)" "unprognostic (2.71e-1)" "unprognostic (2.39e-1)" "unprognostic (1.36e-1)" "unprognostic (1.01e-1)" "unprognostic (2.58e-1)" "unprognostic (1.12e-1)" "unprognostic (5.34e-2)" HNRNPH1 "hnRNPH, HNRPH1" ENSG00000169045 "Heterogeneous nuclear ribonucleoprotein H1" P31943 5 179614178-179634784 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglia: 366.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000914, HPA001359, HPA016884, CAB032820" Supported Enhanced Nucleoplasm NA NA 850000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 15: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 97: Non-specific - Cellular respiration" 289 Nucleoplasm "CAB032820: , HPA000914: , HPA001359: , HPA016884: " "unprognostic (5.36e-2)" "unprognostic (4.53e-1)" "unprognostic (6.70e-2)" "unprognostic (2.20e-1)" "unprognostic (1.55e-2)" "unprognostic (3.88e-1)" "unprognostic (1.60e-1)" "unprognostic (1.77e-1)" "unprognostic (2.75e-3)" "potential prognostic unfavorable (2.18e-4)" "unprognostic (1.90e-2)" "unprognostic (2.66e-3)" "unprognostic (2.21e-1)" "potential prognostic unfavorable (7.08e-10)" "unprognostic (1.56e-1)" "unprognostic (1.39e-1)" "unprognostic (9.87e-2)" "unprognostic (2.74e-1)" "unprognostic (5.25e-2)" "unprognostic (1.51e-1)" "unprognostic (7.76e-2)" "unprognostic (1.75e-2)" "unprognostic (4.13e-3)" "unprognostic (1.00e-2)" "unprognostic (2.00e-3)" "unprognostic (1.27e-2)" "unprognostic (3.11e-2)" "unprognostic (2.41e-1)" "unprognostic (2.69e-1)" "unprognostic (3.54e-1)" "unprognostic (8.08e-2)" HNRNPH2 "FTP3, hnRNPH', HNRPH', HNRPH2" ENSG00000126945 "Heterogeneous nuclear ribonucleoprotein H2" P55795 X 101408222-101414133 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ribonucleoprotein, RNA-binding" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 184.4;Neutrophils: 202.2;Syncytiotrophoblasts: 389.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000914, HPA001359, CAB004436, HPA016884" Supported Enhanced Nucleoplasm NA NA 380000 "Cluster 28: Neutrophils - Unknown function" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 36: Non-specific - mRNA processing" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 42 Nucleoplasm "CAB004436: , HPA000914: , HPA001359: , HPA016884: " "unprognostic (1.23e-1)" "unprognostic (8.43e-2)" "unprognostic (1.48e-1)" "unprognostic (1.18e-1)" "unprognostic (2.16e-1)" "unprognostic (1.46e-1)" "unprognostic (5.56e-2)" "unprognostic (1.38e-1)" "unprognostic (6.16e-2)" "unprognostic (1.05e-2)" "potential prognostic favorable (3.37e-6)" "unprognostic (1.18e-2)" "unprognostic (9.77e-2)" "unprognostic (2.01e-2)" "unprognostic (5.43e-2)" "unprognostic (1.39e-1)" "unprognostic (1.87e-2)" "unprognostic (2.08e-1)" "unprognostic (7.47e-2)" "unprognostic (1.29e-1)" "unprognostic (3.13e-2)" "unprognostic (5.67e-2)" "unprognostic (1.42e-1)" "unprognostic (1.37e-1)" "unprognostic (3.51e-1)" "unprognostic (3.89e-1)" "unprognostic (1.30e-1)" "unprognostic (1.47e-1)" "unprognostic (3.52e-2)" "unprognostic (3.40e-1)" "unprognostic (1.33e-1)" HNRNPH3 "2H9, HNRPH3" ENSG00000096746 "Heterogeneous nuclear ribonucleoprotein H3" P31942 10 68331174-68343193 "Plasma proteins, Predicted intracellular proteins" "mRNA processing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038264 Supported Nucleoplasm NA NA 56000 "Cluster 33: Non-specific - ATP binding" "Cluster 65: Brain - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 17: Non-specific - RNA processing" 36 Nucleoplasm "HPA038264: " "unprognostic (3.73e-2)" "unprognostic (3.49e-2)" "unprognostic (4.02e-1)" "unprognostic (2.70e-2)" "unprognostic (3.95e-1)" "unprognostic (2.25e-1)" "unprognostic (1.16e-1)" "unprognostic (3.20e-1)" "unprognostic (5.65e-2)" "potential prognostic unfavorable (7.56e-4)" "validated prognostic favorable (5.65e-5)" "validated prognostic favorable (1.31e-6)" "unprognostic (5.73e-2)" "potential prognostic unfavorable (1.32e-8)" "unprognostic (4.55e-2)" "potential prognostic unfavorable (9.25e-5)" "unprognostic (1.21e-2)" "unprognostic (3.76e-1)" "unprognostic (2.88e-1)" "unprognostic (1.85e-1)" "unprognostic (4.38e-1)" "unprognostic (1.79e-2)" "unprognostic (4.89e-3)" "unprognostic (7.04e-2)" "unprognostic (2.74e-1)" "unprognostic (8.23e-2)" "unprognostic (1.38e-1)" "unprognostic (1.42e-1)" "unprognostic (1.49e-1)" "unprognostic (2.07e-1)" "unprognostic (5.64e-2)" HNRNPK "CSBP, HNRPK, TUNP" ENSG00000165119 "Heterogeneous nuclear ribonucleoprotein K" P61978 9 83968083-83980631 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor, Ribonucleoprotein, RNA-binding" "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004435, HPA007644, CAB016225, HPA044105" Supported Enhanced Nucleoplasm NA NA 3500000 "Cluster 35: Neutrophils - Protein binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 17: Non-specific - RNA processing" 232 Nucleoplasm "CAB004435: , CAB016225: , HPA007644: , HPA044105: " "unprognostic (2.90e-2)" "unprognostic (8.19e-2)" "unprognostic (5.92e-2)" "unprognostic (6.12e-3)" "unprognostic (1.44e-2)" "unprognostic (1.92e-1)" "unprognostic (2.38e-2)" "unprognostic (1.17e-2)" "unprognostic (8.33e-2)" "unprognostic (1.08e-2)" "validated prognostic favorable (4.38e-7)" "validated prognostic favorable (7.69e-4)" "unprognostic (6.61e-2)" "validated prognostic unfavorable (3.87e-4)" "validated prognostic unfavorable (4.16e-4)" "unprognostic (7.21e-3)" "unprognostic (5.38e-3)" "unprognostic (3.13e-1)" "unprognostic (1.68e-1)" "unprognostic (1.93e-1)" "unprognostic (5.09e-2)" "unprognostic (3.09e-3)" "unprognostic (4.56e-1)" "unprognostic (2.08e-1)" "unprognostic (6.93e-2)" "unprognostic (1.38e-1)" "unprognostic (7.18e-2)" "unprognostic (3.74e-2)" "unprognostic (4.23e-1)" "unprognostic (1.33e-1)" "unprognostic (1.90e-2)" HNRNPL HNRPL ENSG00000104824 "Heterogeneous nuclear ribonucleoprotein L" P14866 19 38836370-38852347 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 57.9;Bergmann glia: 64.1;Distal convoluted tubule cells: 48.8;Microglia: 51.6;Oligodendrocyte progenitor cells: 51.7;Oligodendrocytes: 66.4;Podocytes: 52.4;Proximal tubule cells: 57.7;Renal collecting duct intercalated cells: 49.7;Renal connecting tubule cells: 51.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016326, HPA051748, HPA052661" Supported Enhanced Nucleoplasm NA NA 10000000 "Cluster 13: Non-specific - Mitochondria" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 102: Non-specific - Mixed function" 226 Nucleoplasm "CAB016326: , HPA051748: , HPA052661: " "unprognostic (2.41e-1)" "unprognostic (2.22e-1)" "unprognostic (1.30e-1)" "unprognostic (2.42e-3)" "unprognostic (5.34e-2)" "unprognostic (1.23e-1)" "unprognostic (7.80e-2)" "potential prognostic favorable (1.47e-5)" "unprognostic (1.98e-1)" "potential prognostic unfavorable (9.00e-4)" "potential prognostic favorable (4.98e-6)" "unprognostic (1.00e-2)" "unprognostic (4.12e-2)" "validated prognostic unfavorable (2.39e-5)" "validated prognostic unfavorable (5.31e-4)" "potential prognostic unfavorable (4.08e-5)" "unprognostic (1.92e-2)" "unprognostic (5.98e-2)" "unprognostic (1.27e-1)" "unprognostic (2.35e-1)" "unprognostic (1.80e-1)" "unprognostic (1.61e-2)" "unprognostic (1.89e-1)" "unprognostic (1.89e-1)" "unprognostic (2.14e-2)" "unprognostic (1.15e-1)" "unprognostic (9.61e-2)" "unprognostic (7.91e-2)" "unprognostic (3.97e-1)" "unprognostic (1.23e-1)" "unprognostic (1.18e-1)" HNRNPLL HNRPLL ENSG00000143889 "Heterogeneous nuclear ribonucleoprotein L like" Q8WVV9 2 38561969-38603586 "Predicted intracellular proteins" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 222.9;Neutrophil progenitors: 529.9;Pituicytes/FSCs: 310.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046084 Approved Approved Nucleoplasm,Mitochondria,Cytosol No No "Cluster 3: Non-specific - Nuclear processes" "Cluster 61: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 22 Nucleoplasm "Mitochondria, Cytosol" "HPA046084: " "unprognostic (1.64e-1)" "unprognostic (1.12e-1)" "unprognostic (6.67e-3)" "unprognostic (6.64e-2)" "unprognostic (1.52e-1)" "unprognostic (4.83e-2)" "unprognostic (1.23e-2)" "unprognostic (3.44e-1)" "unprognostic (7.57e-3)" "potential prognostic favorable (3.92e-4)" "unprognostic (5.86e-2)" "unprognostic (3.88e-1)" "potential prognostic unfavorable (5.49e-5)" "unprognostic (8.78e-2)" "unprognostic (6.14e-2)" "unprognostic (2.65e-1)" "unprognostic (3.76e-1)" "unprognostic (7.79e-2)" "unprognostic (5.41e-3)" "unprognostic (3.42e-2)" "unprognostic (1.76e-3)" "unprognostic (3.93e-3)" "unprognostic (1.57e-1)" "unprognostic (1.86e-3)" "unprognostic (9.22e-2)" "unprognostic (2.67e-1)" "unprognostic (8.52e-3)" "unprognostic (1.37e-1)" "unprognostic (8.17e-2)" HNRNPM "CEAR, HNRNPM4, HNRPM, HNRPM4, HTGR1, NAGR1" ENSG00000099783 "Heterogeneous nuclear ribonucleoprotein M" P52272 19 8444767-8489114 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016113, HPA024344" Supported Approved Nucleoplasm NA NA 280000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 49: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 17: Non-specific - RNA processing" 131 Nucleoplasm "CAB016113: , HPA024344: " "unprognostic (4.75e-2)" "unprognostic (2.84e-1)" "unprognostic (1.97e-1)" "unprognostic (3.89e-2)" "unprognostic (4.81e-2)" "unprognostic (2.07e-1)" "unprognostic (8.75e-2)" "unprognostic (4.52e-1)" "unprognostic (1.54e-2)" "unprognostic (6.46e-3)" "validated prognostic favorable (2.10e-6)" "validated prognostic favorable (8.56e-4)" "unprognostic (1.74e-1)" "validated prognostic unfavorable (3.76e-5)" "validated prognostic unfavorable (4.27e-4)" "unprognostic (1.01e-2)" "unprognostic (2.82e-3)" "unprognostic (7.25e-2)" "unprognostic (7.47e-3)" "unprognostic (1.07e-1)" "unprognostic (3.63e-1)" "unprognostic (6.13e-2)" "unprognostic (9.13e-2)" "unprognostic (1.51e-1)" "unprognostic (5.39e-3)" "unprognostic (1.22e-1)" "unprognostic (6.98e-2)" "unprognostic (2.74e-2)" "unprognostic (1.76e-1)" "unprognostic (3.24e-2)" "unprognostic (1.14e-2)" HNRNPR "hnRNP-R, HNRPR" ENSG00000125944 "Heterogeneous nuclear ribonucleoprotein R" O43390 1 23303771-23344336 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011687, HPA026092" Supported Enhanced Nucleoplasm NA NA 270000 "Cluster 33: Non-specific - ATP binding" "Cluster 64: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 102: Non-specific - Mixed function" 129 Nucleoplasm "CAB011687: , HPA026092: " "unprognostic (1.84e-1)" "unprognostic (2.00e-1)" "unprognostic (6.40e-2)" "unprognostic (1.23e-1)" "unprognostic (6.95e-3)" "unprognostic (7.28e-2)" "unprognostic (5.22e-2)" "unprognostic (8.40e-3)" "unprognostic (1.35e-1)" "potential prognostic unfavorable (9.76e-5)" "potential prognostic favorable (1.96e-6)" "unprognostic (5.88e-3)" "unprognostic (1.46e-1)" "potential prognostic unfavorable (5.22e-4)" "unprognostic (5.67e-3)" "unprognostic (2.60e-3)" "potential prognostic unfavorable (5.88e-4)" "unprognostic (2.28e-1)" "unprognostic (4.35e-2)" "unprognostic (5.63e-2)" "unprognostic (1.93e-2)" "potential prognostic unfavorable (6.29e-4)" "unprognostic (1.45e-1)" "unprognostic (5.16e-2)" "unprognostic (1.89e-1)" "unprognostic (8.56e-3)" "unprognostic (1.73e-2)" "unprognostic (1.86e-1)" "unprognostic (2.77e-1)" "unprognostic (3.19e-2)" "unprognostic (5.28e-2)" HNRNPU "C1orf199, FLJ30202, FLJ37978, HNRNPU-AS1, HNRPU, NCRNA00201, SAF-A" ENSG00000153187 "Heterogeneous nuclear ribonucleoprotein U" Q00839 1 244840638-244864560 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Cell division, Differentiation, Host-virus interaction, Mitosis, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, DNA-binding, Repressor, Ribonucleoprotein, RNA-binding" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011532, HPA041057, HPA058707" Supported Supported Nucleoplasm NA NA 3800000 "Cluster 30: Non-specific - DNA binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 103: Non-specific - Basic cellular processes" 290 Nucleoplasm "CAB011532: , HPA041057: , HPA058707: " "unprognostic (7.68e-3)" "unprognostic (1.05e-1)" "unprognostic (1.27e-1)" "unprognostic (3.20e-2)" "unprognostic (2.21e-2)" "unprognostic (8.80e-2)" "unprognostic (3.65e-2)" "unprognostic (6.63e-2)" "unprognostic (1.23e-1)" "unprognostic (3.79e-2)" "potential prognostic favorable (3.04e-6)" "unprognostic (6.02e-3)" "unprognostic (4.25e-2)" "validated prognostic unfavorable (6.53e-5)" "validated prognostic unfavorable (6.75e-4)" "potential prognostic unfavorable (2.96e-4)" "unprognostic (1.33e-1)" "unprognostic (1.16e-2)" "unprognostic (1.14e-2)" "unprognostic (3.99e-2)" "unprognostic (2.61e-1)" "unprognostic (1.56e-1)" "unprognostic (1.59e-2)" "unprognostic (4.61e-2)" "unprognostic (1.51e-1)" "unprognostic (2.20e-1)" "unprognostic (2.63e-2)" "unprognostic (5.99e-2)" "unprognostic (1.11e-1)" "unprognostic (1.65e-1)" "unprognostic (1.81e-1)" HNRNPUL1 "E1B-AP5, E1BAP5, FLJ12944, HNRPUL1" ENSG00000105323 "Heterogeneous nuclear ribonucleoprotein U like 1" Q9BUJ2 19 41262496-41307787 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Repressor, Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046290, CAB046477, HPA049475" Enhanced Enhanced Nucleoplasm NA NA 21000 "Cluster 45: Eosinophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 78 Nucleoplasm "CAB046477: , HPA046290: , HPA049475: " "unprognostic (1.09e-2)" "unprognostic (8.20e-2)" "unprognostic (2.31e-1)" "unprognostic (1.22e-1)" "unprognostic (2.76e-2)" "unprognostic (1.24e-1)" "unprognostic (9.11e-2)" "unprognostic (3.45e-1)" "unprognostic (6.00e-2)" "unprognostic (8.74e-2)" "unprognostic (1.77e-3)" "unprognostic (1.16e-2)" "unprognostic (2.15e-1)" "unprognostic (1.94e-3)" "unprognostic (5.74e-2)" "unprognostic (1.52e-2)" "unprognostic (2.32e-2)" "unprognostic (1.40e-2)" "unprognostic (2.49e-2)" "unprognostic (9.81e-2)" "unprognostic (6.72e-2)" "unprognostic (1.33e-1)" "unprognostic (5.49e-2)" "unprognostic (2.21e-1)" "unprognostic (2.59e-1)" "unprognostic (1.55e-1)" "unprognostic (4.19e-2)" "unprognostic (2.55e-1)" "unprognostic (1.29e-1)" "unprognostic (3.49e-2)" "unprognostic (1.30e-1)" HNRNPUL2 "DKFZp762N1910, HNRPUL2" ENSG00000214753 "Heterogeneous nuclear ribonucleoprotein U like 2" Q1KMD3 11 62712630-62727457 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 8.2;Megakaryocyte progenitors: 10.4" "Low cell type specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041632, HPA056696, HPA067699" Supported Enhanced Nucleoplasm NA NA 51000 "Cluster 30: Non-specific - DNA binding" "Cluster 2: Non-specific - Mixed function" "Cluster 34: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 50 Nucleoplasm "HPA041632: , HPA056696: , HPA067699: " "unprognostic (1.56e-2)" "unprognostic (2.40e-2)" "unprognostic (6.95e-2)" "potential prognostic unfavorable (8.43e-4)" "unprognostic (9.48e-2)" "unprognostic (1.86e-1)" "unprognostic (4.07e-2)" "unprognostic (9.81e-2)" "unprognostic (2.12e-1)" "unprognostic (2.59e-3)" "potential prognostic favorable (2.74e-6)" "unprognostic (1.29e-2)" "unprognostic (3.14e-2)" "potential prognostic unfavorable (7.45e-4)" "unprognostic (2.51e-2)" "unprognostic (6.43e-3)" "unprognostic (7.77e-2)" "unprognostic (1.08e-1)" "unprognostic (1.67e-1)" "unprognostic (6.08e-2)" "unprognostic (1.25e-1)" "unprognostic (1.50e-2)" "unprognostic (3.80e-3)" "unprognostic (8.70e-2)" "unprognostic (1.37e-1)" "unprognostic (9.55e-2)" "unprognostic (1.64e-1)" "unprognostic (7.88e-3)" "unprognostic (1.54e-1)" "unprognostic (2.05e-1)" "unprognostic (1.71e-1)" HOATZ "C11orf88, FLJ46266" ENSG00000183644 "HOATZ cilia and flagella associated protein" Q6PI97 11 111514778-111537043 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "choroid plexus: 158.9;fallopian tube: 80.8" "Group enriched" "Detected in some" 4 "Endometrial ciliated cells: 870.4;Epididymal efferent duct ciliated cells: 431.9;Fallopian tube ciliated cells: 1079.5;Late primary spermatocytes: 310.9;Respiratory ciliated cells: 1027.8" "Cell type enriched" "Detected in some" 4 "ependymal cell: 235.9" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 14.1" "Region enhanced" "Detected in all" "choroid plexus: 68.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 5.2;Kidney cancer: 2.8" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "midbrain: 11.7" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 5: Rhabdoid - Unknown function" "Cluster 107: Ciliated cells - Cilia assembly & function" "validated prognostic unfavorable (1.40e-4)" "validated prognostic unfavorable (6.44e-4)" "unprognostic (1.26e-1)" "unprognostic (5.19e-2)" "unprognostic (1.34e-2)" "unprognostic (7.15e-2)" "unprognostic (6.08e-3)" "unprognostic (4.92e-2)" "unprognostic (7.99e-2)" "unprognostic (5.86e-2)" HOGA1 "C10orf65, DHDPS2, DHDPSL, FLJ37472, NPL2" ENSG00000241935 "4-hydroxy-2-oxoglutarate aldolase 1" Q86XE5 10 97584323-97612802 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Lyase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 48.3;liver: 54.1" "Cell type enhanced" "Detected in some" "Astrocytes: 23.1;Bergmann glia: 37.1;Choroid plexus epithelial cells: 72.1;Ependymal cells: 38.8;Late spermatids: 14.7;Oligodendrocytes: 15.4" "Cell type enhanced" "Detected in many" "Bergmann glia: 38.1;choroid plexus epithelial cell: 51.0;ependymal cell: 43.4" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 61.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Kidney cancer: 31.5" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA039466 Approved NA NA 15000 "Cluster 76: Non-specific - Metabolism" "Cluster 25: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 13 "HPA039466: " "unprognostic (9.47e-2)" "unprognostic (5.41e-3)" "potential prognostic favorable (5.19e-4)" "unprognostic (2.70e-1)" "unprognostic (4.08e-2)" "unprognostic (3.19e-1)" "unprognostic (1.96e-2)" "unprognostic (6.73e-2)" "potential prognostic favorable (7.64e-5)" "unprognostic (6.78e-2)" "unprognostic (3.63e-2)" "unprognostic (1.64e-2)" "unprognostic (2.82e-1)" "unprognostic (1.15e-3)" "unprognostic (6.74e-2)" "unprognostic (2.24e-1)" "unprognostic (2.61e-1)" "unprognostic (1.04e-1)" "unprognostic (4.81e-2)" "unprognostic (5.98e-2)" "unprognostic (1.12e-1)" "unprognostic (2.54e-1)" "unprognostic (1.21e-1)" "unprognostic (1.44e-2)" "unprognostic (6.13e-3)" "unprognostic (3.30e-1)" HOMER1 "HOMER-1B, SYN47, Ves-1" ENSG00000152413 "Homer scaffold protein 1" Q86YM7 5 79372636-79514134 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.6;skeletal muscle: 31.9" "Cell type enhanced" "Detected in many" "Epicardial cells: 934.7;Salivary myoepithelial cells: 595.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004437, HPA036521, HPA036522" Enhanced Supported Approved Cytosol No No "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 34: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 103: Non-specific - Basic cellular processes" 42 Cytosol "CAB004437: , HPA036521: , HPA036522: " "unprognostic (1.42e-1)" "unprognostic (2.23e-1)" "unprognostic (3.26e-2)" "unprognostic (9.11e-2)" "unprognostic (4.63e-2)" "unprognostic (7.39e-2)" "unprognostic (2.84e-1)" "unprognostic (1.93e-1)" "unprognostic (1.56e-1)" "unprognostic (1.46e-1)" "unprognostic (1.67e-1)" "unprognostic (6.03e-2)" "unprognostic (1.05e-1)" "unprognostic (2.58e-3)" "potential prognostic unfavorable (3.86e-4)" "unprognostic (9.57e-3)" "potential prognostic unfavorable (4.11e-4)" "unprognostic (8.29e-3)" "unprognostic (9.57e-2)" "unprognostic (2.37e-1)" "unprognostic (5.80e-2)" "unprognostic (1.46e-3)" "unprognostic (9.38e-2)" "unprognostic (1.05e-1)" "unprognostic (1.16e-1)" "unprognostic (1.10e-2)" "unprognostic (4.51e-1)" "unprognostic (5.93e-2)" "unprognostic (1.66e-1)" "unprognostic (2.70e-2)" "unprognostic (2.53e-1)" HOMER2 "CPD, Cupidin, DFNA68, HOMER-2, HOMER-2A, HOMER-2B, Vesl-2" ENSG00000103942 "Homer scaffold protein 2" Q9NSB8 15 82836946-82986153 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hearing "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 213.3" "Cell type enhanced" "Detected in many" "Cholangiocytes: 341.3;Choroid plexus epithelial cells: 284.0;Endometrial ciliated cells: 340.3;Endometrial glandular cells: 249.8;Endometrial luminal cells: 278.6;Lacrimal acinar cells: 800.8;Myonuclei: 261.4;Pancreatic acinar cells: 302.0;Prostatic glandular cells: 488.2;Salivary acinar cells: 336.9" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 290.2" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 118.4" "Region enhanced" "Detected in all" "choroid plexus: 162.3" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.1" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in all" "prostate cancer: 80.8" "Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Skeletal muscle - Skeletal myocytes, Skin - Eccrine sweat gland cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040134, CAB079014" Uncertain Supported Supported Cytosol NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 23: Choroid plexus - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 10 Cytosol "CAB079014: , HPA040134: " "unprognostic (1.25e-1)" "unprognostic (1.16e-1)" "unprognostic (5.44e-2)" "unprognostic (4.86e-2)" "unprognostic (4.95e-2)" "unprognostic (1.95e-1)" "unprognostic (1.68e-1)" "unprognostic (4.27e-3)" "unprognostic (6.69e-2)" "unprognostic (8.24e-3)" "unprognostic (7.44e-2)" "unprognostic (4.27e-2)" "unprognostic (3.86e-1)" "unprognostic (4.22e-3)" "potential prognostic favorable (2.59e-5)" "unprognostic (8.09e-3)" "unprognostic (1.25e-2)" "unprognostic (2.33e-1)" "unprognostic (1.06e-2)" "unprognostic (2.10e-1)" "unprognostic (6.71e-2)" "unprognostic (8.39e-2)" "unprognostic (7.84e-2)" "unprognostic (1.81e-1)" "unprognostic (3.95e-1)" "unprognostic (7.01e-2)" "unprognostic (3.22e-1)" "unprognostic (1.05e-1)" "unprognostic (1.11e-1)" "unprognostic (2.07e-2)" HOMER3 HOMER-3 ENSG00000051128 "Homer scaffold protein 3" Q9NSC5 19 18929201-18941261 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial secretory cells: 5.5;Lymphatic endothelial cells: 11.2;monocytes: 5.4;Ocular epithelial cells: 10.3;Retinal pigment epithelial cells: 8.5" "Cell type enhanced" "Detected in some" "Bergmann glia: 6.2;cerebellar inhibitory: 19.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 15.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Liver - Vascular endothelial cells" "Region enriched" "Detected in all" 6 "cerebellum: 189.2" "Low region specificity" "Detected in all" "CAB032656, HPA040999, CAB079015" Enhanced Supported Supported "Plasma membrane,Cytosol,Cytoplasmic bodies" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 24: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 67: Plasma cells - Plasma cell differentiation" 85 Cytosol "Plasma membrane, Cytoplasmic bodies" "CAB032656: , CAB079015: , HPA040999: " "unprognostic (5.02e-2)" "unprognostic (1.89e-1)" "unprognostic (5.91e-3)" "unprognostic (3.14e-1)" "unprognostic (4.00e-3)" "unprognostic (4.85e-2)" "unprognostic (3.42e-1)" "unprognostic (2.15e-2)" "unprognostic (3.93e-2)" "unprognostic (1.28e-1)" "unprognostic (2.38e-3)" "unprognostic (8.86e-2)" "unprognostic (2.88e-2)" "potential prognostic unfavorable (2.20e-5)" "unprognostic (1.05e-1)" "unprognostic (8.22e-2)" "unprognostic (2.61e-3)" "unprognostic (1.67e-3)" "unprognostic (1.70e-1)" "unprognostic (2.13e-1)" "unprognostic (4.66e-2)" "unprognostic (5.38e-2)" "unprognostic (1.50e-3)" "unprognostic (1.49e-2)" "unprognostic (5.79e-2)" "unprognostic (1.36e-2)" "unprognostic (8.11e-3)" "unprognostic (1.84e-2)" "unprognostic (8.23e-2)" "unprognostic (2.19e-2)" "unprognostic (3.57e-2)" HOMEZ KIAA1443 ENSG00000290292 "Homeobox and leucine zipper encoding" Q8IX15 14 23272422-23299796 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Early spermatids: 355.9;Esophageal apical cells: 118.2;Late primary spermatocytes: 181.2;Late spermatids: 91.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036316, HPA036317" Enhanced Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 39: Testis - Nuclear processes" "Cluster 6: Non-specific - Immune response" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 6 Nucleoli "Nucleoplasm, Cytosol" "HPA036316: , HPA036317: " HOOK1 HK1 ENSG00000134709 "Hook microtubule tethering protein 1" Q9UJC3 1 59814786-59876322 "Predicted intracellular proteins" "Differentiation, Protein transport, Spermatogenesis, Transport" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 46.7" "Group enriched" "Detected in many" 5 "Early spermatids: 786.4;Late spermatids: 1305.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 6.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary gland basal cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "HPA018537, HPA018820" Enhanced NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 42: Retina - Visual perception" "Cluster 5: Non-specific - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 58 "HPA018537: , HPA018820: " "unprognostic (3.96e-2)" "unprognostic (5.92e-2)" "unprognostic (5.33e-2)" "unprognostic (1.53e-1)" "validated prognostic favorable (8.68e-5)" "validated prognostic favorable (4.16e-4)" "unprognostic (1.97e-1)" "potential prognostic favorable (5.38e-4)" "unprognostic (3.12e-3)" "potential prognostic favorable (5.60e-8)" "unprognostic (4.15e-3)" "unprognostic (1.91e-1)" "unprognostic (8.30e-2)" "unprognostic (1.04e-1)" "unprognostic (2.66e-1)" "unprognostic (2.16e-1)" "unprognostic (5.92e-2)" "unprognostic (3.20e-1)" "unprognostic (8.06e-2)" "unprognostic (1.98e-1)" "unprognostic (1.44e-1)" "unprognostic (1.83e-1)" "unprognostic (1.86e-2)" "unprognostic (4.42e-3)" "unprognostic (3.57e-2)" "unprognostic (8.92e-2)" "unprognostic (8.97e-2)" "unprognostic (9.64e-2)" "unprognostic (1.54e-1)" "unprognostic (5.75e-3)" HOOK2 HK2 ENSG00000095066 "Hook microtubule tethering protein 2" Q96ED9 19 12763003-12872740 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 6 "Epicardial cells: 3431.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043519, HPA050351" Approved Supported Vesicles,Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 70: Non-specific - Protein processing" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 27 "Vesicles, Cytosol" "HPA043519: , HPA050351: " "unprognostic (3.52e-1)" "unprognostic (1.76e-1)" "unprognostic (3.10e-3)" "unprognostic (2.60e-1)" "unprognostic (1.41e-1)" "unprognostic (2.21e-2)" "unprognostic (1.76e-1)" "unprognostic (3.22e-3)" "unprognostic (3.64e-3)" "unprognostic (2.31e-2)" "unprognostic (5.95e-3)" "unprognostic (4.59e-3)" "potential prognostic favorable (3.46e-5)" "unprognostic (1.92e-1)" "unprognostic (4.43e-1)" "unprognostic (6.54e-2)" "unprognostic (2.40e-1)" "unprognostic (1.16e-1)" "unprognostic (1.75e-1)" "unprognostic (1.08e-1)" "unprognostic (1.90e-1)" "potential prognostic favorable (5.55e-4)" "unprognostic (1.79e-2)" "unprognostic (4.54e-2)" "potential prognostic favorable (4.35e-4)" "unprognostic (2.15e-1)" "unprognostic (1.25e-1)" "unprognostic (5.40e-3)" "unprognostic (2.77e-1)" "unprognostic (5.58e-2)" "unprognostic (3.90e-2)" HOOK3 HK3 ENSG00000168172 "Hook microtubule tethering protein 3" Q86VS8 8 42896946-43030535 "Cancer-related genes, Predicted intracellular proteins" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Urothelial cells: 553.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024756 Approved Supported "Golgi apparatus,Centriolar satellite,Cytosol" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 69: Urothelial cells - Basic cellular functions" 31 "Centriolar satellite" "Golgi apparatus, Cytosol" "HPA024756: " "unprognostic (1.80e-2)" "unprognostic (1.95e-2)" "unprognostic (1.57e-1)" "unprognostic (7.09e-3)" "unprognostic (2.07e-1)" "unprognostic (2.47e-1)" "unprognostic (1.67e-1)" "unprognostic (3.26e-2)" "unprognostic (1.47e-2)" "unprognostic (1.46e-3)" "potential prognostic favorable (5.92e-4)" "unprognostic (1.72e-2)" "unprognostic (1.20e-1)" "unprognostic (3.51e-1)" "unprognostic (4.55e-2)" "unprognostic (1.51e-1)" "unprognostic (1.77e-1)" "unprognostic (8.28e-2)" "unprognostic (2.03e-1)" "unprognostic (1.76e-3)" "unprognostic (3.42e-3)" "unprognostic (6.00e-2)" "unprognostic (7.27e-2)" "unprognostic (2.30e-1)" "unprognostic (4.03e-1)" "unprognostic (2.11e-1)" "unprognostic (1.04e-1)" "unprognostic (4.60e-2)" "unprognostic (4.96e-1)" "unprognostic (3.21e-2)" "unprognostic (4.66e-2)" HOPX "HOP, LAGY, NECC1, OB1, SMAP31" ENSG00000171476 "HOP homeobox" Q9BPY8 4 56647988-56681899 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, Repressor" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 712.1;skin 1: 1401.9" "Cell type enriched" "Detected in many" 10 "Esophageal apical cells: 29333.9" "Cell type enhanced" "Detected in all" "hippocampal CA4: 296.1" "Group enriched" "Detected in all" 4 "Glioblastoma Multiforme (TCGA): 487.0;Lung Adenocarcinoma (TCGA): 493.9;Thyroid Carcinoma (TCGA): 356.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "gdT-cell: 519.4;NK-cell: 783.5" "Group enriched" "Detected in all" 15 "NK-cells: 783.5;T-cells: 519.4" "Cancer enhanced" "Detected in many" "lymphoma: 25.4" "Colon - Smooth muscle cells, Stomach - Chief cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018632, HPA030180" Enhanced Approved "Nuclear bodies,Cytosol" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 9: Skin - Hair follicle development" "Cluster 53: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 84: Apical squamous epithelium - Cornification" 4 "Nuclear bodies" Cytosol "CAB018632: , HPA030180: " "unprognostic (1.18e-3)" "unprognostic (4.02e-1)" "unprognostic (7.60e-2)" "unprognostic (1.66e-2)" "unprognostic (2.25e-3)" "unprognostic (1.15e-1)" "unprognostic (1.45e-1)" "unprognostic (2.58e-3)" "unprognostic (1.23e-2)" "unprognostic (5.41e-2)" "unprognostic (3.27e-2)" "unprognostic (2.95e-2)" "unprognostic (1.78e-3)" "unprognostic (3.12e-1)" "unprognostic (2.45e-1)" "unprognostic (1.34e-2)" "unprognostic (2.66e-1)" "unprognostic (7.13e-3)" "unprognostic (1.65e-1)" "unprognostic (2.61e-1)" "unprognostic (1.10e-2)" "unprognostic (9.80e-2)" "unprognostic (1.38e-1)" "unprognostic (3.71e-1)" "unprognostic (2.20e-2)" "unprognostic (6.29e-3)" "unprognostic (9.27e-2)" "unprognostic (2.32e-2)" "unprognostic (1.28e-1)" "unprognostic (9.51e-2)" "unprognostic (7.84e-3)" HORMAD1 "CT46, DKFZP434A1315" ENSG00000143452 "HORMA domain containing 1" Q86X24 1 150698060-150720895 "Predicted intracellular proteins" "Differentiation, Meiosis, Oogenesis, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "testis: 110.1" "Group enriched" "Detected in many" 4 "Early primary spermatocytes: 771.5;Late primary spermatocytes: 549.3" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 12.7" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "neutrophil: 1.2" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 18.2" "Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA028346, HPA037850" Enhanced Approved Nucleoplasm,Nucleoli Yes No "Cluster 57: Testis - Spermatogenesis" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 3: Early primary spermatocytes - Early meiosis" 3 Nucleoplasm Nucleoli "HPA028346: , HPA037850: " "unprognostic (9.82e-2)" "unprognostic (1.94e-2)" "unprognostic (1.52e-1)" "unprognostic (1.14e-1)" "unprognostic (1.42e-3)" "unprognostic (4.17e-2)" "unprognostic (2.18e-1)" "unprognostic (2.22e-2)" "unprognostic (1.20e-1)" "unprognostic (8.18e-2)" "unprognostic (7.94e-2)" "unprognostic (6.40e-2)" "unprognostic (2.37e-2)" "unprognostic (2.18e-1)" HORMAD2 "CT46.2, MGC26710" ENSG00000176635 "HORMA domain containing 2" Q8N7B1 22 30080464-30177075 "Predicted intracellular proteins" Meiosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 21.3" "Group enriched" "Detected in some" 4 "Early primary spermatocytes: 237.4;Late primary spermatocytes: 176.1" "Group enriched" "Detected in some" 6 "astrocyte: 9.0;Bergmann glia: 9.8;ependymal cell: 3.5;oligodendrocyte precursor cell: 3.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Spermatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA003074, HPA043880" Enhanced Supported Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 65: Non-specific - Unknown function" "Cluster 3: Early primary spermatocytes - Early meiosis" 4 Nucleoplasm "Centrosome, Cytosol" "HPA003074: , HPA043880: " "potential prognostic unfavorable (3.27e-4)" HOXA1 "HOX1, HOX1F" ENSG00000105991 "Homeobox A1" 7 27092993-27096000 "Human disease related genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "urinary bladder: 5.0" "Cell type enriched" "Detected in some" 4 "Tuft cells: 46.1" "Cell type enhanced" "Detected in single" "fibroblast: 1.2" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 11 "medulla oblongata: 2.5;pons: 1.1;spinal cord: 1.6;white matter: 1.6" "Group enriched" "Detected in some" 6 "intermediate monocyte: 4.5;NK-cell: 4.8;non-classical monocyte: 7.0" "Group enriched" "Detected in many" 6 "monocytes: 7.0;NK-cells: 4.8" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 7 "pons and medulla: 1.0" "Region enhanced" "Detected in some" "spinal cord: 4.2" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 43: Hindbrain - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 95: Tuft cells - Chemosensory signaling" 18 "unprognostic (6.92e-2)" "unprognostic (5.19e-3)" "potential prognostic unfavorable (4.13e-4)" "unprognostic (1.18e-1)" "unprognostic (9.05e-2)" "unprognostic (4.98e-2)" "unprognostic (3.14e-3)" "potential prognostic unfavorable (3.52e-5)" "unprognostic (4.57e-2)" "unprognostic (2.90e-2)" "unprognostic (3.18e-3)" "unprognostic (3.67e-2)" "unprognostic (1.65e-2)" "unprognostic (2.03e-1)" "unprognostic (3.47e-2)" "unprognostic (9.35e-2)" "unprognostic (3.08e-2)" "unprognostic (3.08e-1)" "unprognostic (2.18e-1)" "unprognostic (2.29e-1)" "unprognostic (1.16e-2)" HOXA10 "HOX1, HOX1H" ENSG00000253293 "Homeobox A10" P31260 7 27170605-27180261 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 44.8;endometrium 1: 66.9;skeletal muscle: 60.5" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 1.2;Endometrial stromal cells: 6.1;Innate lymphoid cells: 1.6;Megakaryocyte progenitors: 1.4;Megakaryocyte-Erythroid progenitors: 1.1;Prostatic club cells: 1.4;Prostatic glandular cells: 2.7;Prostatic hillock cells: 1.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "basophil: 8.4;NK-cell: 10.7" "Group enriched" "Detected in many" 5 "granulocytes: 8.4;NK-cells: 10.7" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast), Kidney - Fibroblasts" "Not detected" "Not detected" "Region enriched" "Detected in single" 140 "spinal cord: 24.4" "CAB019384, HPA071918" Approved Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 15: Kidney cancer - Membrane components" "Cluster 108: Fibroblasts - ECM organization" 5 Nucleoplasm "Nuclear bodies" "CAB019384: , HPA071918: " "unprognostic (7.30e-2)" "unprognostic (4.27e-2)" "unprognostic (3.17e-1)" "unprognostic (1.28e-2)" "unprognostic (4.32e-2)" "unprognostic (6.45e-2)" "unprognostic (7.41e-2)" "unprognostic (3.33e-1)" "unprognostic (1.90e-3)" "unprognostic (8.90e-2)" "unprognostic (2.13e-1)" "unprognostic (1.67e-1)" "unprognostic (9.99e-2)" "unprognostic (3.29e-2)" "unprognostic (5.18e-3)" "unprognostic (3.68e-3)" "unprognostic (1.38e-1)" "unprognostic (1.31e-1)" "unprognostic (2.68e-2)" "unprognostic (8.61e-3)" "unprognostic (2.79e-1)" "unprognostic (1.78e-3)" "unprognostic (2.59e-2)" "unprognostic (3.97e-1)" "unprognostic (4.24e-1)" "unprognostic (4.42e-3)" "unprognostic (1.96e-2)" "unprognostic (1.03e-2)" "unprognostic (1.92e-1)" "unprognostic (7.36e-2)" HOXA11 "HOX1, HOX1I" ENSG00000005073 "Homeobox A11" P31270 7 27181157-27185232 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 52.4;endometrium 1: 80.2;smooth muscle: 38.5" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 9.6;Decidual stromal cells: 31.1;Endometrial stromal cells: 97.2;Prostatic club cells: 18.4;Prostatic hillock cells: 12.5;Smooth muscle cells: 9.4;Tuft cells: 11.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Testis - Early spermatids" "Not detected" "Not detected" "Region enriched" "Detected in single" 56 "spinal cord: 5.6" "HPA006770, HPA035623" Enhanced Supported Nucleoplasm NA NA "Cluster 75: Ovary - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 108: Fibroblasts - ECM organization" 3 Nucleoplasm "HPA006770: , HPA035623: " "unprognostic (7.48e-2)" "unprognostic (2.16e-1)" "unprognostic (9.40e-2)" "unprognostic (9.67e-2)" "unprognostic (2.04e-2)" "unprognostic (4.27e-2)" "unprognostic (1.30e-1)" "potential prognostic unfavorable (7.46e-5)" "unprognostic (5.03e-3)" "unprognostic (1.54e-1)" "unprognostic (1.29e-3)" "unprognostic (1.64e-1)" "unprognostic (3.63e-1)" "unprognostic (3.74e-3)" "unprognostic (2.22e-1)" "unprognostic (1.97e-1)" "unprognostic (2.34e-1)" "potential prognostic unfavorable (8.08e-4)" "potential prognostic unfavorable (7.65e-5)" "unprognostic (3.28e-2)" "unprognostic (9.82e-2)" "unprognostic (4.33e-2)" HOXA13 "HOX1, HOX1J" ENSG00000106031 "Homeobox A13" P31271 7 27193503-27200091 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 21.0;placenta: 16.0;prostate: 20.9;seminal vesicle: 21.9" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 26.5;Colonocytes: 37.9;Enteric stem cells: 11.8;Enteric transient amplifying cells: 11.4;Gastric progenitor cells: 21.8;Goblet cells: 9.5;Prostatic club cells: 44.5;Prostatic glandular cells: 36.4;Prostatic hillock cells: 44.9;Smooth muscle cells: 13.2;Tuft cells: 23.1;Urothelial cells: 8.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 14.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 9.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046098, HPA069061" Supported "Nucleoplasm,Mitotic chromosome,Intermediate filaments" Yes NA "Cluster 75: Ovary - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 2 Nucleoplasm "Mitotic chromosome, Intermediate filaments" "HPA046098: , HPA069061: " "unprognostic (2.65e-2)" "unprognostic (3.30e-1)" "unprognostic (6.36e-2)" "unprognostic (1.46e-1)" "unprognostic (1.23e-3)" "unprognostic (1.79e-1)" "unprognostic (3.06e-1)" "unprognostic (2.35e-1)" "unprognostic (2.84e-1)" "unprognostic (1.01e-2)" "unprognostic (2.97e-2)" "unprognostic (3.50e-1)" "unprognostic (1.19e-1)" "unprognostic (2.48e-3)" "unprognostic (3.33e-3)" "unprognostic (1.64e-1)" HOXA2 HOX1K ENSG00000105996 "Homeobox A2" O43364 7 27100354-27102686 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 4.3;Epididymal basal cells: 5.0;Epididymal clear cells: 4.1;Epididymal efferent duct absorptive cells: 15.6;Epididymal efferent duct ciliated cells: 5.9;Esophageal basal cells: 4.2;Medullary thymic epithelial cells: 4.8;Mesothelial cells: 4.2;Submucosal glandular cells: 3.7;Tuft cells: 11.5" "Cell type enhanced" "Detected in some" "ependymal cell: 3.1;lower rhombic lip: 3.4" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 22 "medulla oblongata: 9.7;pons: 6.5;spinal cord: 10.2;white matter: 8.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 36 "pons and medulla: 5.8" "Region enhanced" "Detected in some" "medulla oblongata: 9.5;spinal cord: 10.6" HPA078220 Approved Nucleoplasm,Vesicles Yes NA "Cluster 22: Epididymis - Mixed function" "Cluster 43: Hindbrain - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 15: Non-specific - Protein processing" 1 "Nucleoplasm, Vesicles" "HPA078220: " "unprognostic (4.68e-2)" "unprognostic (6.43e-2)" "unprognostic (1.54e-1)" "unprognostic (1.15e-1)" "unprognostic (8.47e-2)" "potential prognostic unfavorable (6.26e-4)" "potential prognostic unfavorable (8.31e-8)" "unprognostic (2.43e-1)" "unprognostic (5.47e-3)" "unprognostic (1.69e-2)" "unprognostic (1.20e-1)" "unprognostic (8.87e-2)" "unprognostic (4.84e-3)" "unprognostic (5.20e-3)" "unprognostic (1.04e-1)" "unprognostic (2.67e-1)" HOXA3 "HOX1, HOX1E" ENSG00000105997 "Homeobox A3" O43365 7 27106184-27152583 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Epididymal efferent duct absorptive cells: 41.7;Hematopoietic stem cells: 43.7;Late spermatids: 92.4;Loop of henle epithelial cells: 62.5;Renal connecting tubule cells: 65.2;Tuft cells: 57.6" "Cell type enhanced" "Detected in some" "ependymal cell: 10.2;lower rhombic lip: 21.2" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 33.4" "Group enriched" "Detected in some" 19 "medulla oblongata: 22.4;pons: 16.4;spinal cord: 19.8;white matter: 14.6" "Immune cell enhanced" "Detected in single" "neutrophil: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Stomach - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in single" 34 "pons and medulla: 3.3" "Region enhanced" "Detected in some" "medulla oblongata: 5.1;spinal cord: 4.1" HPA029157 Uncertain Supported Nucleoplasm NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 43: Hindbrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 2 Nucleoplasm "HPA029157: " "unprognostic (2.31e-2)" "unprognostic (9.07e-2)" "potential prognostic favorable (8.29e-4)" "potential prognostic unfavorable (7.40e-4)" "unprognostic (2.32e-1)" "unprognostic (3.41e-2)" "unprognostic (1.63e-2)" "unprognostic (1.04e-3)" "unprognostic (2.06e-2)" "unprognostic (8.93e-2)" "potential prognostic unfavorable (6.25e-4)" "unprognostic (1.76e-1)" "unprognostic (1.21e-1)" "unprognostic (4.66e-2)" "unprognostic (8.52e-3)" "potential prognostic unfavorable (5.95e-4)" "unprognostic (2.04e-2)" "unprognostic (1.45e-1)" "unprognostic (4.25e-3)" "unprognostic (5.67e-3)" "unprognostic (1.16e-1)" "unprognostic (1.52e-1)" "unprognostic (2.19e-1)" "unprognostic (3.13e-2)" "unprognostic (5.32e-2)" "unprognostic (4.53e-2)" "unprognostic (1.99e-2)" "unprognostic (1.66e-1)" "unprognostic (2.92e-1)" "unprognostic (8.03e-2)" HOXA4 "HOX1, HOX1D" ENSG00000197576 "Homeobox A4" Q00056 7 27128507-27130780 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.2" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 30.5" "Group enriched" "Detected in many" 19 "medulla oblongata: 41.5;pons: 34.7;spinal cord: 32.7;white matter: 29.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 24.1" "Colon - Enteric glia cells, Thyroid gland - Fibroblasts" "Region enriched" "Detected in single" 46 "pons and medulla: 11.3" HPA060088 Approved Supported "Nuclear bodies" NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 43: Hindbrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 108: Fibroblasts - ECM organization" "Nuclear bodies" "HPA060088: " "unprognostic (9.71e-3)" "unprognostic (9.78e-2)" "unprognostic (6.98e-2)" "unprognostic (2.17e-2)" "unprognostic (2.93e-3)" "unprognostic (2.63e-2)" "unprognostic (4.69e-2)" "unprognostic (1.22e-2)" "unprognostic (3.16e-2)" "unprognostic (4.35e-3)" "potential prognostic favorable (3.81e-4)" "unprognostic (4.28e-2)" "unprognostic (3.40e-2)" "unprognostic (1.79e-1)" "unprognostic (1.25e-1)" "unprognostic (4.68e-1)" "unprognostic (1.33e-1)" "unprognostic (9.28e-2)" "unprognostic (2.83e-1)" "unprognostic (3.29e-2)" "unprognostic (8.63e-2)" "unprognostic (2.10e-1)" "unprognostic (4.12e-2)" "unprognostic (1.44e-1)" "potential prognostic unfavorable (1.08e-4)" "unprognostic (5.11e-2)" "unprognostic (5.08e-1)" "unprognostic (4.49e-3)" "unprognostic (3.25e-1)" "unprognostic (7.29e-3)" "unprognostic (1.61e-3)" HOXA5 "HOX1, HOX1C" ENSG00000106004 "Homeobox A5" P20719 7 27141052-27143681 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 77.6;epididymis: 46.2;fallopian tube: 55.4" "Cell type enhanced" "Detected in some" "Adrenal cortex cells: 2.5;Basal prostatic cells: 3.9;Breast lactating cells: 1.5;Breast myoepithelial cells: 4.3;Epididymal efferent duct absorptive cells: 2.5;Epididymal principal cells: 1.1;Fibroblasts: 1.4;Hematopoietic stem cells: 1.9;Innate lymphoid cells: 2.2;Prostatic club cells: 1.1;Smooth muscle cells: 1.6;Thymic myoid cells: 1.4" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 46 "medulla oblongata: 84.5;pons: 22.5;spinal cord: 52.7;white matter: 35.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Vascular endothelial cells, Testis - Early spermatids" "Region enriched" "Detected in single" 220 "pons and medulla: 22.0" "Group enriched" "Detected in some" 33 "medulla oblongata: 5.7;spinal cord: 21.4" NA NA "Cluster 32: Basophils - Transcription" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 43: Hindbrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 108: Fibroblasts - ECM organization" 10 "unprognostic (2.15e-1)" "unprognostic (2.52e-1)" "unprognostic (2.39e-2)" "unprognostic (1.15e-3)" "unprognostic (2.06e-1)" "unprognostic (4.33e-2)" "unprognostic (1.55e-1)" "unprognostic (2.57e-3)" "unprognostic (1.15e-1)" "unprognostic (8.18e-2)" "unprognostic (3.05e-2)" "unprognostic (6.22e-3)" "unprognostic (1.44e-1)" "unprognostic (1.69e-2)" "unprognostic (2.50e-1)" "unprognostic (9.74e-2)" "unprognostic (5.15e-2)" "unprognostic (3.79e-2)" "unprognostic (4.03e-3)" "unprognostic (2.10e-2)" "unprognostic (1.02e-1)" "unprognostic (5.58e-2)" "unprognostic (2.02e-1)" "unprognostic (2.15e-2)" "potential prognostic unfavorable (6.58e-4)" "unprognostic (2.83e-1)" "unprognostic (6.14e-2)" "unprognostic (2.87e-1)" "unprognostic (4.25e-1)" HOXA6 "HOX1, HOX1B" ENSG00000106006 "Homeobox A6" P31267 7 27145396-27150603 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 11.2" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 1.8;Endometrial stromal cells: 1.9;Hematopoietic stem cells: 4.4;Prostatic club cells: 1.9;Prostatic hillock cells: 1.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 7 "medulla oblongata: 16.7;pons: 5.3;spinal cord: 17.8;white matter: 12.6" "Immune cell enhanced" "Detected in single" "basophil: 3.1" "Lineage enhanced" "Detected in single" "granulocytes: 3.1" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 34 "pons and medulla: 3.3" "HPA004203, HPA077900" Approved Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 43: Hindbrain - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 108: Fibroblasts - ECM organization" Nucleoplasm "Nuclear speckles" "HPA004203: , HPA077900: " "unprognostic (4.33e-2)" "unprognostic (9.10e-3)" "unprognostic (4.16e-3)" "unprognostic (2.55e-1)" "unprognostic (6.38e-2)" "unprognostic (2.61e-1)" "unprognostic (1.73e-3)" "unprognostic (4.07e-3)" "unprognostic (1.46e-3)" "unprognostic (6.13e-2)" "unprognostic (1.41e-1)" "unprognostic (3.13e-1)" "unprognostic (3.14e-1)" "unprognostic (5.85e-2)" "unprognostic (1.20e-3)" "unprognostic (1.20e-1)" "unprognostic (1.66e-3)" HOXA7 "HOX1, HOX1A" ENSG00000122592 "Homeobox A7" P31268 7 27153716-27157936 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Epididymal basal cells: 24.0;Epididymal clear cells: 32.7;Epididymal efferent duct absorptive cells: 80.5;Epididymal efferent duct ciliated cells: 23.5;Epididymal principal cells: 34.8;Late primary spermatocytes: 63.3;Oocytes: 92.1;Smooth muscle cells: 34.8;Thymic myoid cells: 27.2" "Cell type enhanced" "Detected in some" "committed oligodendrocyte precursor: 1.7;ependymal cell: 1.7;oligodendrocyte precursor cell: 1.7" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 5 "medulla oblongata: 10.2;spinal cord: 17.6;white matter: 10.9" "Immune cell enriched" "Detected in single" 6 "NK-cell: 4.7" "Lineage enriched" "Detected in single" 6 "NK-cells: 4.7" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells" "Region enriched" "Detected in single" 12 "pons and medulla: 1.3" "Region enriched" "Detected in some" 6 "spinal cord: 28.1" HPA074048 Supported "Nucleoplasm,Nuclear membrane" NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 43: Hindbrain - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 15: Non-specific - Protein processing" 1 Nucleoplasm "Nuclear membrane" "HPA074048: " "unprognostic (2.25e-1)" "unprognostic (1.99e-1)" "unprognostic (3.83e-3)" "unprognostic (2.48e-1)" "unprognostic (2.67e-1)" "unprognostic (9.97e-2)" "unprognostic (2.14e-1)" "unprognostic (7.38e-3)" "unprognostic (1.35e-1)" "unprognostic (1.40e-1)" "unprognostic (1.96e-3)" "potential prognostic favorable (6.60e-4)" "unprognostic (3.25e-3)" "unprognostic (7.89e-3)" "unprognostic (1.26e-1)" "unprognostic (3.59e-1)" "unprognostic (4.44e-3)" "unprognostic (4.88e-2)" "unprognostic (4.98e-2)" "unprognostic (6.01e-2)" "unprognostic (6.11e-3)" "unprognostic (1.21e-1)" "potential prognostic unfavorable (3.31e-4)" "unprognostic (1.94e-1)" "unprognostic (2.02e-1)" "unprognostic (6.44e-2)" "unprognostic (9.80e-2)" HOXA9 "HOX1, HOX1G" ENSG00000078399 "Homeobox A9" P31269 7 27162438-27175180 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 27.0" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 35.8;Enteric stem cells: 26.1;Epididymal principal cells: 36.8;Goblet cells: 24.5;Hematopoietic stem cells: 50.9;Innate lymphoid cells: 25.9;Megakaryocyte-Erythroid progenitors: 22.2;Neuroendocrine cells: 24.8;Podocytes: 29.7;Prostatic club cells: 38.2;Prostatic hillock cells: 34.7;Renal connecting tubule cells: 27.8;Thymocytes: 22.0" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "basophil: 6.7;myeloid DC: 5.6;NK-cell: 11.6" "Group enriched" "Detected in many" 6 "dendritic cells: 5.6;granulocytes: 6.7;NK-cells: 11.6" "Cancer enhanced" "Detected in many" "colorectal cancer: 56.5;Kidney cancer: 53.0" "Not detected" "Not detected" "Region enriched" "Detected in single" 191 "spinal cord: 19.0" "HPA061982, HPA076200" Uncertain Enhanced Nucleoplasm NA NA "Cluster 32: Basophils - Transcription" "Cluster 58: Skin - Keratinization" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 14 Nucleoplasm "HPA061982: , HPA076200: " "unprognostic (3.28e-2)" "unprognostic (2.50e-1)" "unprognostic (2.62e-3)" "unprognostic (1.15e-2)" "unprognostic (1.59e-1)" "unprognostic (7.84e-2)" "unprognostic (1.61e-1)" "unprognostic (1.22e-1)" "unprognostic (1.05e-1)" "unprognostic (3.16e-1)" "unprognostic (2.80e-2)" "unprognostic (9.40e-2)" "unprognostic (1.58e-2)" "unprognostic (3.18e-3)" "unprognostic (2.74e-1)" "unprognostic (1.34e-3)" "unprognostic (3.04e-2)" "unprognostic (2.80e-1)" "unprognostic (8.24e-3)" "unprognostic (1.76e-1)" "unprognostic (5.69e-2)" "unprognostic (9.72e-2)" HOXB1 "HOX2, HOX2I" ENSG00000120094 "Homeobox B1" P14653 17 48528526-48531011 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Esophageal apical cells: 3.8;Esophageal suprabasal cells: 1.7;Late primary spermatocytes: 2.5" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 13 "Testicular Germ Cell Tumor (TCGA): 6.7" "Region enhanced" "Detected in single" "spinal cord: 1.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA036648, HPA044576, HPA073858" Uncertain Enhanced Nucleoplasm NA NA "Cluster 43: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" 16 Nucleoplasm "HPA036648: , HPA044576: , HPA073858: " "unprognostic (4.86e-1)" HOXB13 ENSG00000159184 "Homeobox B13" Q92826 17 48724763-48728750 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 12 "intestine: 38.7;prostate: 77.3" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 26.5;Colonocytes: 140.1;Enteric stem cells: 57.5;Enteric transient amplifying cells: 54.0;Goblet cells: 64.3;Neuroendocrine cells: 64.4;Prostatic club cells: 25.4;Prostatic glandular cells: 138.5" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 11 "Prostate Adenocarcinoma (TCGA): 297.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 7 "prostate cancer: 151.6" "Prostate - Prostate glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB004438, HPA062852, HPA065019" Enhanced Enhanced Nucleoplasm NA NA "Cluster 38: Non-specific - Basic cellular processes" "Cluster 60: Prostate cancer - Unknown function" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 3 Nucleoplasm "CAB004438: , HPA062852: , HPA065019: " "potential prognostic unfavorable (7.48e-4)" "unprognostic (3.68e-2)" "unprognostic (2.17e-1)" "unprognostic (1.03e-1)" "unprognostic (7.60e-2)" "unprognostic (8.17e-3)" "unprognostic (6.37e-3)" "unprognostic (2.01e-3)" "unprognostic (2.51e-2)" "unprognostic (1.61e-2)" "unprognostic (4.74e-2)" "unprognostic (2.54e-1)" "unprognostic (2.83e-2)" "unprognostic (2.08e-1)" "unprognostic (1.30e-3)" "unprognostic (2.71e-2)" "unprognostic (4.30e-2)" "unprognostic (2.79e-2)" "unprognostic (1.50e-3)" "unprognostic (4.63e-2)" "unprognostic (7.31e-2)" "unprognostic (6.25e-2)" HOXB2 "HOX2, HOX2H" ENSG00000173917 "Homeobox B2" P14652 17 48540894-48545109 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 60.3;Endometrial secretory cells: 57.7;Epididymal basal cells: 89.0;Epididymal efferent duct absorptive cells: 132.5;Epididymal efferent duct ciliated cells: 83.1;Epididymal principal cells: 240.0;Esophageal apical cells: 81.9;Fallopian secretory cells: 72.3;Fallopian tube ciliated cells: 68.1" "Cell type enhanced" "Detected in many" "fibroblast: 16.0;leukocyte: 15.2;lower rhombic lip: 15.9" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 18 "medulla oblongata: 31.9;pons: 18.6;spinal cord: 25.1;white matter: 21.7" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells" "Region enriched" "Detected in single" 34 "pons and medulla: 4.4" "Group enriched" "Detected in some" 4 "medulla oblongata: 8.9;spinal cord: 12.2" HPA047857 Supported Nucleoplasm NA NA "Cluster 11: T-cells - Unknown function" "Cluster 22: Epididymis - Mixed function" "Cluster 43: Hindbrain - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 6 Nucleoplasm "HPA047857: " "unprognostic (1.47e-2)" "unprognostic (3.84e-2)" "unprognostic (9.13e-3)" "unprognostic (9.17e-2)" "unprognostic (1.02e-2)" "unprognostic (1.06e-2)" "validated prognostic unfavorable (4.00e-4)" "validated prognostic unfavorable (5.76e-4)" "unprognostic (1.70e-1)" "unprognostic (2.02e-2)" "unprognostic (1.13e-2)" "unprognostic (7.82e-2)" "unprognostic (9.29e-2)" "unprognostic (3.33e-2)" "unprognostic (5.24e-2)" "unprognostic (2.25e-1)" "unprognostic (1.51e-1)" "unprognostic (3.08e-2)" "unprognostic (8.62e-2)" "unprognostic (4.80e-3)" "unprognostic (8.39e-3)" "unprognostic (2.39e-1)" "unprognostic (6.16e-2)" "unprognostic (2.43e-1)" "unprognostic (7.03e-2)" "unprognostic (3.35e-1)" "unprognostic (2.74e-1)" "unprognostic (2.65e-1)" "unprognostic (1.71e-1)" "unprognostic (3.65e-2)" "unprognostic (1.30e-2)" HOXB3 "HOX2, HOX2G" ENSG00000120093 "Homeobox B3" P14651 17 48548870-48604912 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 66.6" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 207.0;Epididymal principal cells: 93.7;Loop of henle epithelial cells: 245.1;Papillary tip epithelial cells: 211.9;Renal collecting duct intercalated cells: 217.9;Renal collecting duct principal cells: 354.9;Renal connecting tubule cells: 243.7" "Cell type enhanced" "Detected in many" "ependymal cell: 21.6;lower rhombic lip: 27.4;splatter: 20.9" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 27 "medulla oblongata: 61.5;pons: 27.8;spinal cord: 51.7;white matter: 29.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 40 "pons and medulla: 8.8" "Group enriched" "Detected in some" 22 "medulla oblongata: 11.5;pons: 4.4;spinal cord: 14.3" "CAB009860, HPA064990" Approved Supported Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 22: Epididymis - Mixed function" "Cluster 43: Hindbrain - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 1 Nucleoplasm "CAB009860: , HPA064990: " "unprognostic (4.49e-2)" "unprognostic (4.10e-2)" "unprognostic (1.51e-2)" "unprognostic (6.40e-2)" "unprognostic (2.56e-1)" "unprognostic (1.68e-1)" "unprognostic (1.17e-2)" "potential prognostic unfavorable (2.58e-4)" "unprognostic (2.77e-1)" "unprognostic (1.23e-2)" "unprognostic (1.21e-1)" "unprognostic (9.37e-2)" "unprognostic (6.05e-2)" "unprognostic (1.69e-2)" "unprognostic (1.49e-2)" "unprognostic (2.49e-3)" "unprognostic (2.21e-2)" "unprognostic (2.81e-2)" "unprognostic (3.26e-2)" "unprognostic (7.11e-3)" "unprognostic (2.93e-1)" "unprognostic (6.36e-2)" "unprognostic (2.20e-1)" "unprognostic (1.37e-1)" "unprognostic (1.07e-1)" "unprognostic (1.38e-1)" "unprognostic (4.18e-2)" "unprognostic (2.79e-2)" "unprognostic (8.43e-2)" "unprognostic (6.50e-2)" "unprognostic (9.31e-2)" HOXB4 "HOX2, HOX2F" ENSG00000182742 "Homeobox B4" P17483 17 48575507-48578350 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Epididymal efferent duct absorptive cells: 1.2;Fallopian tube ciliated cells: 1.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 30 "medulla oblongata: 24.7;pons: 9.5;spinal cord: 19.4;white matter: 12.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skin - Endothelial cells" "Region enriched" "Detected in single" 36 "pons and medulla: 3.6" "Group enriched" "Detected in many" 6 "medulla oblongata: 9.3;spinal cord: 12.2" HPA057432 Uncertain Supported Nucleoplasm,Centrosome NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 43: Hindbrain - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 1 Nucleoplasm Centrosome "HPA057432: " "unprognostic (2.31e-1)" "unprognostic (1.71e-2)" "unprognostic (8.66e-3)" "unprognostic (1.86e-1)" "unprognostic (6.83e-3)" "unprognostic (1.34e-1)" "unprognostic (2.24e-2)" "unprognostic (2.68e-3)" "unprognostic (1.24e-1)" "unprognostic (7.39e-2)" "unprognostic (4.95e-2)" "unprognostic (8.55e-2)" "unprognostic (4.10e-2)" "unprognostic (1.53e-2)" "unprognostic (1.29e-2)" "unprognostic (4.87e-2)" "unprognostic (2.28e-3)" "unprognostic (1.76e-1)" "unprognostic (1.44e-3)" "unprognostic (3.59e-1)" "unprognostic (7.83e-2)" "unprognostic (2.20e-1)" "unprognostic (1.79e-2)" "unprognostic (7.86e-2)" "unprognostic (6.34e-2)" "unprognostic (1.25e-1)" "unprognostic (1.72e-1)" "unprognostic (2.87e-2)" HOXB5 "HOX2, HOX2A" ENSG00000120075 "Homeobox B5" P09067 17 48591257-48593779 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 17.4;intestine: 16.9;kidney: 33.0" "Cell type enhanced" "Detected in single" "Kupffer cells: 1.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 35.7" "Region enhanced" "Detected in some" "medulla oblongata: 84.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Fibroblasts_1, Stomach - Fibroblasts" "Region enriched" "Detected in single" 230 "pons and medulla: 22.9" "Group enriched" "Detected in some" 9 "medulla oblongata: 24.1;spinal cord: 18.5" "HPA043851, HPA074454" Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 43: Hindbrain - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 50 Nucleoplasm "Nucleoli fibrillar center, Cytosol" "HPA043851: , HPA074454: " "unprognostic (8.95e-2)" "unprognostic (6.31e-2)" "unprognostic (8.49e-2)" "unprognostic (1.42e-1)" "unprognostic (2.90e-1)" "unprognostic (2.13e-1)" "unprognostic (2.14e-3)" "unprognostic (2.55e-1)" "unprognostic (2.34e-1)" "unprognostic (1.45e-2)" "unprognostic (5.46e-2)" "unprognostic (4.42e-2)" "unprognostic (3.61e-3)" "unprognostic (3.08e-1)" "unprognostic (5.67e-3)" "unprognostic (2.90e-1)" "unprognostic (1.20e-3)" "unprognostic (3.51e-1)" "unprognostic (3.35e-2)" "unprognostic (2.67e-1)" "unprognostic (2.54e-2)" "unprognostic (1.20e-1)" "unprognostic (7.12e-2)" "unprognostic (2.08e-3)" "unprognostic (3.30e-1)" "unprognostic (3.23e-2)" HOXB6 "HOX2, HOX2B" ENSG00000108511 "Homeobox B6" P17509 17 48595751-48604992 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 38.0;kidney: 57.8" "Cell type enhanced" "Detected in some" "Colonocytes: 3.1;Endometrial ciliated cells: 4.6;Endometrial glandular cells: 3.2;Endometrial luminal cells: 3.6;Endometrial secretory cells: 5.8;Epididymal efferent duct absorptive cells: 4.1;Epididymal efferent duct ciliated cells: 2.5;Epididymal principal cells: 4.0;Fallopian secretory cells: 3.3;Fallopian tube ciliated cells: 4.9;Loop of henle epithelial cells: 2.7;Papillary tip epithelial cells: 2.6;Renal collecting duct principal cells: 2.7;Tuft cells: 23.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 68.1" "Group enriched" "Detected in many" 17 "medulla oblongata: 27.6;spinal cord: 49.4;white matter: 14.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 53.5" "Lung - Fibroblasts_1, Minor Salivary Gland - Macrophages, Prostate - Endothelial cells" "Region enriched" "Detected in single" 102 "pons and medulla: 10.1" "Group enriched" "Detected in some" 251 "medulla oblongata: 12.2;spinal cord: 37.9" HPA042063 Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 43: Hindbrain - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 20 Nucleoplasm "Golgi apparatus" "HPA042063: " "unprognostic (3.65e-2)" "unprognostic (4.39e-2)" "unprognostic (1.58e-1)" "unprognostic (1.70e-1)" "unprognostic (3.08e-1)" "unprognostic (5.95e-2)" "unprognostic (2.68e-2)" "unprognostic (1.50e-2)" "unprognostic (1.61e-1)" "unprognostic (1.41e-2)" "unprognostic (2.50e-1)" "unprognostic (2.62e-2)" "unprognostic (2.23e-1)" "unprognostic (1.46e-3)" "unprognostic (6.77e-2)" "unprognostic (3.46e-2)" "unprognostic (2.81e-1)" "unprognostic (1.19e-2)" "unprognostic (7.73e-2)" "unprognostic (3.35e-2)" "unprognostic (2.00e-1)" "unprognostic (8.38e-2)" "unprognostic (6.47e-2)" "unprognostic (1.78e-2)" "unprognostic (8.19e-3)" "unprognostic (7.81e-2)" "unprognostic (1.31e-2)" HOXB7 "HOX2, HOX2C" ENSG00000260027 "Homeobox B7" P09629 17 48607232-48633572 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "epididymis: 127.6" "Cell type enhanced" "Detected in many" "Colonocytes: 119.4;Endometrial ciliated cells: 69.7;Endometrial glandular cells: 76.4;Endometrial luminal cells: 85.5;Endometrial secretory cells: 65.5;Enteric transient amplifying cells: 80.1;Enterocytes: 123.8;Epididymal basal cells: 79.5;Epididymal clear cells: 65.3;Epididymal efferent duct absorptive cells: 157.2;Epididymal efferent duct ciliated cells: 82.7;Epididymal principal cells: 435.4;Goblet cells: 79.0" "Cell type enhanced" "Detected in some" "ependymal cell: 2.5;splatter: 5.4" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 35 "medulla oblongata: 11.5;spinal cord: 27.9;white matter: 15.6" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Minor Salivary Gland - Macrophages, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells" "Region enriched" "Detected in single" 58 "pons and medulla: 5.7" "Region enriched" "Detected in some" 7 "spinal cord: 29.1" HPA049940 Uncertain Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 22: Epididymis - Mixed function" "Cluster 22: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" 14 "Nucleoplasm, Nuclear bodies" Cytosol "HPA049940: " "unprognostic (1.43e-1)" "unprognostic (1.29e-1)" "unprognostic (6.70e-2)" "unprognostic (1.68e-1)" "unprognostic (6.05e-2)" "unprognostic (5.37e-2)" "validated prognostic unfavorable (4.46e-4)" "validated prognostic unfavorable (3.67e-4)" "unprognostic (7.58e-2)" "unprognostic (1.51e-2)" "unprognostic (2.98e-1)" "unprognostic (1.89e-1)" "unprognostic (3.25e-1)" "unprognostic (7.77e-3)" "unprognostic (3.15e-2)" "unprognostic (1.56e-3)" "unprognostic (2.06e-2)" "unprognostic (4.65e-1)" "unprognostic (2.39e-1)" "unprognostic (7.44e-2)" "unprognostic (1.36e-2)" "unprognostic (5.68e-3)" "unprognostic (8.09e-3)" "unprognostic (8.20e-2)" "unprognostic (2.83e-2)" "unprognostic (2.92e-1)" "unprognostic (2.62e-2)" "unprognostic (2.45e-1)" "unprognostic (4.42e-3)" HOXB8 "HOX2, HOX2D" ENSG00000120068 "Homeobox B8" P17481 17 48611377-48615292 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 40.1;epididymis: 45.4;kidney: 33.0" "Group enriched" "Detected in some" 4 "Endometrial secretory cells: 4.9;Epididymal basal cells: 7.9;Epididymal efferent duct absorptive cells: 7.1;Epididymal efferent duct ciliated cells: 2.9;Epididymal principal cells: 10.7" "Cell type enriched" "Detected in single" 20 "splatter: 2.1" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 57.4" "Region enhanced" "Detected in some" "spinal cord: 243.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 50.1" "Breast - Adipocytes (Breast)" "Region enriched" "Detected in single" 65 "pons and medulla: 6.5" "Region enriched" "Detected in all" 5 "spinal cord: 66.1" HPA075905 Supported Nucleoplasm NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 22: Non-specific - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" 1 Nucleoplasm "HPA075905: " "unprognostic (1.19e-2)" "unprognostic (8.44e-2)" "unprognostic (2.58e-1)" "unprognostic (5.49e-3)" "unprognostic (2.52e-1)" "unprognostic (8.15e-2)" "unprognostic (2.33e-2)" "unprognostic (1.87e-3)" "unprognostic (5.46e-3)" "unprognostic (1.25e-1)" "unprognostic (1.31e-1)" "unprognostic (3.49e-3)" "unprognostic (1.85e-1)" "unprognostic (1.38e-1)" "unprognostic (2.50e-3)" "unprognostic (2.42e-1)" "unprognostic (3.22e-2)" "unprognostic (8.35e-2)" "unprognostic (1.06e-1)" "unprognostic (2.01e-3)" "unprognostic (3.20e-3)" "unprognostic (2.94e-2)" "unprognostic (5.35e-2)" "unprognostic (1.98e-2)" HOXB9 "HOX2, HOX2E" ENSG00000170689 "Homeobox B9" P17482 17 48621156-48626358 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 83.0;intestine: 24.7;kidney: 22.0" "Group enriched" "Detected in some" 4 "Endometrial secretory cells: 6.8;Epididymal basal cells: 9.7;Epididymal clear cells: 4.1;Epididymal efferent duct absorptive cells: 9.3;Epididymal efferent duct ciliated cells: 3.8;Epididymal principal cells: 11.7;Neuroendocrine cells: 6.3;Tuft cells: 11.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 80.5;Rectum Adenocarcinoma (TCGA): 68.6" "Group enriched" "Detected in some" 15 "spinal cord: 6.1;white matter: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 64.6" "Colon - Colon enterocytes" "Not detected" "Not detected" "Region enriched" "Detected in single" 190 "spinal cord: 19.0" HPA004928 Supported Nucleoplasm NA No "Cluster 22: Epididymis - Mixed function" "Cluster 22: Non-specific - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 95: Tuft cells - Chemosensory signaling" 54 Nucleoplasm "HPA004928: " "unprognostic (3.00e-2)" "unprognostic (1.54e-1)" "unprognostic (4.19e-2)" "unprognostic (2.69e-1)" "unprognostic (1.26e-1)" "unprognostic (5.56e-2)" "potential prognostic unfavorable (2.39e-5)" "unprognostic (6.07e-2)" "potential prognostic unfavorable (6.68e-5)" "unprognostic (4.78e-3)" "unprognostic (5.63e-2)" "potential prognostic unfavorable (8.90e-4)" "unprognostic (2.08e-1)" "unprognostic (2.54e-2)" "unprognostic (2.46e-1)" "unprognostic (1.29e-2)" "unprognostic (1.65e-1)" "unprognostic (1.90e-3)" "unprognostic (5.94e-2)" "unprognostic (3.78e-1)" "unprognostic (7.73e-2)" "unprognostic (4.29e-3)" "unprognostic (8.98e-2)" "unprognostic (1.51e-1)" "potential prognostic unfavorable (3.24e-4)" HOXC10 HOX3I ENSG00000180818 "Homeobox C10" Q9NYD6 12 53985065-53990279 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 23.2;kidney: 27.7;skeletal muscle: 106.3" "Cell type enhanced" "Detected in single" "Breast myoepithelial cells: 1.7" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Region enriched" "Detected in single" 418 "spinal cord: 41.7" HPA053919 Uncertain Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 27: Breast cancer - Unknown function" "Cluster 108: Fibroblasts - ECM organization" 1 "Nuclear bodies" Nucleoplasm "HPA053919: " "unprognostic (2.35e-1)" "unprognostic (9.50e-3)" "unprognostic (8.15e-2)" "unprognostic (1.94e-1)" "unprognostic (2.35e-3)" "potential prognostic unfavorable (1.73e-5)" "unprognostic (1.37e-1)" "unprognostic (3.40e-1)" "validated prognostic favorable (8.51e-5)" "validated prognostic favorable (2.40e-6)" "unprognostic (2.48e-3)" "unprognostic (1.19e-1)" "unprognostic (3.56e-1)" "unprognostic (1.27e-2)" "unprognostic (8.33e-2)" "unprognostic (1.09e-2)" "potential prognostic unfavorable (1.86e-4)" "unprognostic (4.04e-2)" "potential prognostic unfavorable (7.75e-4)" "unprognostic (7.11e-2)" "unprognostic (3.43e-2)" "unprognostic (4.85e-2)" "unprognostic (1.85e-1)" HOXC11 HOX3H ENSG00000123388 "Homeobox C11" O43248 12 53973126-53977643 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "blood vessel: 4.1;skin 1: 4.7" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 4.3;Early primary spermatocytes: 5.2;Enterocytes: 3.2;Gastric progenitor cells: 9.0;Myosatellite cells: 2.6;Schwann cells: 1.5;Smooth muscle cells: 5.2;Suprabasal keratinocytes: 1.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 15.8;breast cancer: 14.9" "Adipose subcutaneous - Smooth muscle cells, Testis - Spermatocytes" "Not detected" "Not detected" "Region enriched" "Detected in single" 14 "spinal cord: 1.4" HPA038291 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 65: Non-specific - Unknown function" "Cluster 108: Fibroblasts - ECM organization" 4 Nucleoplasm Cytosol "HPA038291: " "unprognostic (1.56e-1)" "unprognostic (1.82e-3)" "unprognostic (2.99e-2)" "unprognostic (1.23e-2)" "unprognostic (3.14e-3)" "unprognostic (3.58e-3)" "unprognostic (7.34e-3)" "potential prognostic unfavorable (2.43e-4)" "unprognostic (2.23e-2)" "potential prognostic unfavorable (7.79e-4)" "unprognostic (3.52e-2)" "unprognostic (1.23e-1)" "unprognostic (6.32e-2)" "unprognostic (2.32e-2)" "unprognostic (2.54e-2)" "unprognostic (9.19e-2)" "unprognostic (3.90e-3)" "unprognostic (6.68e-2)" "unprognostic (3.52e-3)" "unprognostic (2.28e-2)" "unprognostic (6.92e-2)" "unprognostic (3.80e-2)" HOXC12 "HOC3F, HOX3, HOX3F" ENSG00000123407 "Homeobox C12" P31275 12 53954903-53958956 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 16 "adipose tissue: 1.1;blood vessel: 1.7;skin 1: 2.8" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 1.1;Myosatellite cells: 1.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Breast Invasive Carcinoma (TCGA): 2.9;Stomach Adenocarcinoma (TCGA): 3.0" "Region enriched" "Detected in single" 5 "cerebral cortex: 2.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 14.8;breast cancer: 8.8" "Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA055632 Uncertain NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 65: Non-specific - Unknown function" "Cluster 26: Keratinocytes - Keratinization" "HPA055632: " "unprognostic (7.00e-2)" "unprognostic (1.86e-2)" "unprognostic (9.10e-2)" "unprognostic (2.56e-1)" "unprognostic (5.01e-2)" HOXC13 "HOX3, HOX3G" ENSG00000123364 "Homeobox C13" P31276 12 53938831-53946544 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "skin 1: 9.2" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 1.2;Breast hormone-responsive cells: 1.0;Breast myoepithelial cells: 9.5;Differentiating spermatogonia: 2.1;Oocytes: 4.6;Suprabasal keratinocytes: 2.2;Undifferentiated spermatogonia: 1.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 8.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skin - Hair cortex cells, Skin - Inner root sheath cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA051634 Enhanced NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 26: Keratinocytes - Keratinization" 2 "HPA051634: " "unprognostic (9.26e-2)" "unprognostic (1.63e-3)" "unprognostic (1.66e-1)" "unprognostic (1.04e-1)" "unprognostic (2.92e-3)" "potential prognostic unfavorable (8.32e-4)" "unprognostic (3.09e-3)" "unprognostic (2.23e-1)" "unprognostic (1.03e-1)" "unprognostic (2.38e-1)" "unprognostic (2.97e-1)" "unprognostic (3.76e-1)" "unprognostic (2.98e-1)" "unprognostic (1.53e-2)" HOXC4 "HOX3, HOX3E" ENSG00000198353 "Homeobox C4" P09017 12 54016931-54056030 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 21.9" "Cell type enhanced" "Detected in many" "Early spermatids: 53.2;Endometrial ciliated cells: 17.2;Epididymal efferent duct ciliated cells: 20.1;Fallopian tube ciliated cells: 121.1;Late spermatids: 55.3;Loop of henle epithelial cells: 32.8;Podocytes: 18.3;Proximal tubule cells: 18.0;Smooth muscle cells: 16.6" "Cell type enriched" "Detected in some" 8 "lower rhombic lip: 26.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "pons: 34.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipose progenitor cells, Colon - Enteric glia cells, Lung - Fibroblasts_2" "Region enriched" "Detected in single" 24 "pons and medulla: 9.4" "Group enriched" "Detected in some" 64 "medulla oblongata: 6.4;pons: 4.8;spinal cord: 7.8" HPA053910 Supported Nucleoplasm NA NA "Cluster 75: Ovary - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 107: Ciliated cells - Cilia assembly & function" 30 Nucleoplasm "HPA053910: " "unprognostic (3.13e-1)" "unprognostic (3.68e-3)" "unprognostic (1.84e-1)" "unprognostic (3.42e-2)" "unprognostic (1.03e-3)" "unprognostic (6.49e-2)" "unprognostic (8.65e-2)" "unprognostic (3.58e-1)" "unprognostic (7.47e-2)" "unprognostic (3.23e-2)" "unprognostic (1.25e-1)" "unprognostic (1.89e-2)" "unprognostic (1.48e-1)" "unprognostic (1.44e-2)" "unprognostic (1.04e-1)" "unprognostic (1.76e-1)" "unprognostic (2.26e-1)" "unprognostic (4.73e-3)" "unprognostic (9.30e-2)" "unprognostic (6.14e-2)" "unprognostic (7.29e-2)" "unprognostic (1.39e-1)" "unprognostic (7.39e-2)" "unprognostic (7.22e-2)" "unprognostic (5.05e-2)" HOXC5 "HOX3, HOX3D" ENSG00000172789 "Homeobox C5" Q00444 12 54033050-54035361 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 5.5" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 5.2" "Group enriched" "Detected in some" 14 "medulla oblongata: 5.9;pons: 7.6;spinal cord: 4.2;white matter: 2.5" "Immune cell enhanced" "Detected in single" "gdT-cell: 3.0" "Lineage enriched" "Detected in single" 31 "T-cells: 3.0" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Lung - Fibroblasts_2" "Region enriched" "Detected in single" 46 "pons and medulla: 4.6" "Group enriched" "Detected in some" 5 "medulla oblongata: 2.0;spinal cord: 2.8" HPA026794 Uncertain Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 9 Nucleoplasm "Cell Junctions" "HPA026794: " "unprognostic (1.42e-2)" "unprognostic (2.63e-3)" "unprognostic (1.69e-1)" "unprognostic (3.79e-3)" "unprognostic (7.29e-2)" "unprognostic (8.10e-3)" "potential prognostic favorable (5.05e-4)" "unprognostic (1.62e-1)" "unprognostic (1.64e-1)" "unprognostic (2.05e-1)" "unprognostic (1.59e-2)" "unprognostic (2.16e-1)" "unprognostic (1.14e-1)" "unprognostic (7.45e-2)" "unprognostic (3.02e-3)" "unprognostic (1.02e-2)" HOXC6 "HOX3, HOX3C" ENSG00000197757 "Homeobox C6" P09630 12 53990624-54030823 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 31.0" "Cell type enhanced" "Detected in single" "Smooth muscle cells: 3.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 11 "medulla oblongata: 6.9;pons: 9.4;spinal cord: 6.7;white matter: 3.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 41.4" "Breast - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblasts_2" "Region enriched" "Detected in single" 15 "pons and medulla: 1.4" "Region enriched" "Detected in some" 15 "spinal cord: 14.9" HPA054981 Supported Nucleoplasm,Cytosol No No "Cluster 75: Ovary - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 62: Smooth muscle cells - Muscle contraction" Nucleoplasm Cytosol "HPA054981: " "unprognostic (2.51e-2)" "unprognostic (1.33e-2)" "unprognostic (2.12e-1)" "unprognostic (1.33e-1)" "unprognostic (1.35e-3)" "unprognostic (1.32e-3)" "unprognostic (3.55e-3)" "potential prognostic unfavorable (8.84e-5)" "potential prognostic unfavorable (3.77e-4)" "unprognostic (2.27e-2)" "unprognostic (2.18e-2)" "unprognostic (8.97e-2)" "unprognostic (4.58e-2)" "unprognostic (7.53e-3)" "unprognostic (3.43e-1)" "unprognostic (2.36e-2)" "unprognostic (1.69e-1)" "unprognostic (1.51e-2)" "unprognostic (8.95e-3)" "unprognostic (1.28e-1)" "unprognostic (8.44e-3)" "unprognostic (4.24e-2)" "unprognostic (9.81e-3)" "unprognostic (1.14e-1)" "unprognostic (1.14e-1)" "unprognostic (2.06e-1)" "unprognostic (1.24e-1)" "unprognostic (1.32e-1)" HOXC8 "HOX3, HOX3A" ENSG00000037965 "Homeobox C8" P31273 12 54008985-54012769 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 14.6;skeletal muscle: 14.6" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 1.7;Differentiating spermatogonia: 1.2;Epididymal efferent duct absorptive cells: 2.0;Epididymal efferent duct ciliated cells: 1.3;Fibroblasts: 2.2;Leydig cells: 1.2;pDCs: 1.3;Pericytes: 1.8;Smooth muscle cells: 4.4;Thymic myoid cells: 1.4" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 25.7" "Not detected" "Not detected" "Region enriched" "Detected in single" 144 "spinal cord: 14.3" "HPA028911, CAB037020" Uncertain Approved Nucleoplasm,Microtubules NA NA "Cluster 63: Non-specific - Basic cellular processes" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 82 "Nucleoplasm, Microtubules" "CAB037020: , HPA028911: " "unprognostic (6.42e-3)" "unprognostic (1.02e-1)" "unprognostic (5.74e-2)" "unprognostic (1.35e-1)" "potential prognostic unfavorable (2.44e-4)" "validated prognostic unfavorable (6.11e-4)" "validated prognostic unfavorable (1.76e-6)" "unprognostic (7.66e-3)" "unprognostic (2.96e-1)" "unprognostic (2.71e-2)" "unprognostic (3.94e-2)" "unprognostic (2.33e-1)" "unprognostic (1.28e-1)" "unprognostic (2.06e-2)" "unprognostic (1.88e-2)" "unprognostic (1.29e-2)" "unprognostic (7.80e-2)" "unprognostic (2.78e-1)" HOXC9 "HOX3, HOX3B" ENSG00000180806 "Homeobox C9" P31274 12 53994895-54003337 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 10.7;skeletal muscle: 25.6" "Cell type enhanced" "Detected in some" "Breast hormone-responsive cells: 2.7;Breast myoepithelial cells: 3.4;Differentiating spermatogonia: 4.1;Early primary spermatocytes: 4.4;Extravillous trophoblasts: 3.0;Fibroblasts: 2.9;Melanocytes: 12.4;Oocytes: 13.8;Pericytes: 3.5;Smooth muscle cells: 9.0;Thymic myoid cells: 5.4;Undifferentiated spermatogonia: 10.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 26.6" "Not detected" "Not detected" "Region enriched" "Detected in single" 13 "spinal cord: 10.1" "HPA063965, HPA072160" Enhanced Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 3: Rhabdoid - Membrane components" "Cluster 108: Fibroblasts - ECM organization" 17 Nucleoplasm "HPA063965: , HPA072160: " "potential prognostic unfavorable (1.57e-5)" "unprognostic (2.40e-1)" "unprognostic (2.69e-1)" "unprognostic (2.03e-1)" "potential prognostic unfavorable (7.86e-5)" "unprognostic (5.19e-3)" "potential prognostic unfavorable (1.33e-4)" "unprognostic (1.15e-1)" "unprognostic (7.78e-2)" "unprognostic (1.98e-1)" "unprognostic (1.47e-3)" "unprognostic (4.66e-3)" "unprognostic (1.48e-3)" "unprognostic (1.44e-1)" "unprognostic (3.32e-2)" "unprognostic (2.98e-3)" "unprognostic (8.44e-2)" "unprognostic (2.77e-3)" "unprognostic (7.58e-2)" "unprognostic (4.38e-2)" "unprognostic (2.46e-1)" HOXD1 "HOX4, HOX4G" ENSG00000128645 "Homeobox D1" Q9GZZ0 2 176188668-176190907 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 17.2;epididymis: 7.1" "Cell type enhanced" "Detected in some" "Colonocytes: 27.6;Enteric stem cells: 31.9;Enteric transient amplifying cells: 22.4;Enterocytes: 19.6;Epididymal basal cells: 20.3;Epididymal clear cells: 20.4;Epididymal efferent duct absorptive cells: 59.1;Epididymal efferent duct ciliated cells: 44.5;Epididymal principal cells: 84.5;Fallopian tube ciliated cells: 29.2;Goblet cells: 22.3;Oligodendrocytes: 16.7;Oocytes: 23.0;Paneth cells: 23.2;Tuft cells: 23.1" "Cell type enriched" "Detected in some" 4 "oligodendrocyte: 30.6" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 20.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "ovarian cancer: 3.8" "Lung - Alveolar cells type 2, Testis - Spermatogonia" "Region enriched" "Detected in single" 5 "pons and medulla: 1.1" "Low region specificity" "Detected in many" "HPA040062, HPA056900" Enhanced Nucleoplasm NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 15: Kidney cancer - Membrane components" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" Nucleoplasm "HPA040062: , HPA056900: " "potential prognostic favorable (8.78e-4)" "unprognostic (6.76e-2)" "unprognostic (6.58e-2)" "unprognostic (4.81e-2)" "unprognostic (2.43e-3)" "unprognostic (6.54e-3)" "unprognostic (5.02e-2)" "validated prognostic favorable (3.42e-5)" "validated prognostic favorable (1.63e-4)" "unprognostic (2.43e-1)" "unprognostic (2.25e-2)" "unprognostic (3.16e-1)" "unprognostic (2.12e-1)" "unprognostic (1.45e-1)" "unprognostic (1.05e-1)" "unprognostic (4.39e-1)" "unprognostic (3.75e-2)" "unprognostic (5.62e-2)" "unprognostic (3.19e-1)" "unprognostic (1.15e-1)" "unprognostic (4.88e-2)" "unprognostic (6.10e-2)" HOXD10 "HOX4, HOX4D" ENSG00000128710 "Homeobox D10" P28358 2 176108790-176119937 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 20.7;endometrium 1: 38.4;kidney: 24.2;vagina: 24.8" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 77.9;Colonocytes: 35.3;Decidual stromal cells: 68.0;Distal convoluted tubule cells: 95.1;Endometrial stromal cells: 50.9;Loop of henle epithelial cells: 56.0;Lymphatic endothelial cells: 27.7;Neuroendocrine cells: 38.8;Papillary tip epithelial cells: 36.8;Prostatic club cells: 27.5;Prostatic hillock cells: 33.4;Renal collecting duct principal cells: 96.0;Renal connecting tubule cells: 124.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 27.6;Gallbladder cancer: 24.8" "Not detected" "Not detected" "Region enriched" "Detected in single" 67 "spinal cord: 6.6" HPA065871 Approved "Nucleoplasm,Cytosol,Cytoplasmic bodies" No NA "Cluster 75: Ovary - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 105: Non-specific - Mixed function" 9 Nucleoplasm "Cytosol, Cytoplasmic bodies" "HPA065871: " "unprognostic (5.60e-2)" "unprognostic (1.90e-2)" "unprognostic (1.35e-1)" "unprognostic (1.34e-1)" "unprognostic (4.57e-2)" "unprognostic (1.11e-1)" "unprognostic (1.96e-2)" "unprognostic (4.86e-3)" "unprognostic (1.21e-1)" "unprognostic (2.37e-1)" "unprognostic (2.41e-2)" "unprognostic (1.99e-2)" "potential prognostic unfavorable (2.21e-4)" "unprognostic (1.93e-1)" "unprognostic (1.36e-1)" "unprognostic (2.99e-1)" "unprognostic (6.11e-2)" "unprognostic (2.71e-1)" "unprognostic (1.91e-1)" "unprognostic (1.33e-3)" "unprognostic (2.23e-2)" HOXD11 "HOX4, HOX4F" ENSG00000128713 "Homeobox D11" P31277 2 176104216-176109754 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 3.4;endometrium 1: 6.4;intestine: 3.3;kidney: 5.1;vagina: 4.3" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 12.9;Decidual stromal cells: 12.8;Endometrial stromal cells: 32.4;Neuroendocrine cells: 5.1;Papillary tip epithelial cells: 3.6;Prostatic club cells: 7.6;Prostatic glandular cells: 3.9;Prostatic hillock cells: 6.0;Renal collecting duct principal cells: 4.0;Renal connecting tubule cells: 3.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 15.1" "Kidney - Fibroblasts" "Not detected" "Not detected" "Region enriched" "Detected in single" 31 "spinal cord: 3.1" HPA055155 Supported Nucleoplasm NA NA "Cluster 75: Ovary - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 108: Fibroblasts - ECM organization" Nucleoplasm "HPA055155: " "unprognostic (7.00e-2)" "unprognostic (5.32e-2)" "unprognostic (4.97e-2)" "unprognostic (1.10e-1)" "unprognostic (1.45e-1)" "unprognostic (9.11e-3)" "unprognostic (5.08e-3)" "unprognostic (3.22e-1)" "unprognostic (1.75e-2)" "unprognostic (1.39e-1)" "unprognostic (1.07e-1)" "unprognostic (1.36e-1)" "unprognostic (4.63e-1)" "unprognostic (5.21e-1)" HOXD12 HOX4H ENSG00000170178 "Homeobox D12" P35452 2 176099795-176102489 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 1.4;seminal vesicle: 1.4;vagina: 1.1" "Cell type enhanced" "Detected in some" "Colonocytes: 1.3;Goblet cells: 1.7;Neuroendocrine cells: 5.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Bone cancer: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA059444 Uncertain NA NA "Cluster 77: Intestine - Digestion" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" 2 "HPA059444: " "unprognostic (9.68e-2)" HOXD13 "HOX4I, SPD" ENSG00000128714 "Homeobox D13" P35453 2 176092721-176095944 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "cervix: 11.8;intestine: 15.8;prostate: 9.0;seminal vesicle: 15.3;vagina: 15.1" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 17.7;Colonocytes: 10.9;Enteric stem cells: 6.7;Enteric transient amplifying cells: 10.0;Goblet cells: 9.5;Neuroendocrine cells: 7.8;Prostatic club cells: 16.5;Prostatic glandular cells: 2.9;Prostatic hillock cells: 8.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Bone cancer: 35.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA064064 Approved Nucleoplasm NA NA "Cluster 77: Intestine - Digestion" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 1 Nucleoplasm "HPA064064: " "unprognostic (1.41e-1)" "unprognostic (7.71e-2)" "unprognostic (3.84e-2)" "unprognostic (5.89e-2)" "unprognostic (1.44e-1)" "unprognostic (6.11e-3)" "unprognostic (4.17e-2)" "unprognostic (1.82e-2)" "unprognostic (3.26e-2)" "unprognostic (7.29e-3)" "unprognostic (5.37e-2)" "unprognostic (1.54e-1)" "unprognostic (2.48e-2)" "unprognostic (1.26e-1)" HOXD3 "HOX1D, HOX4, HOX4A" ENSG00000128652 "Homeobox D3" P31249 2 176136612-176173102 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 39.4" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 53.2;Distal convoluted tubule cells: 189.5;Epididymal efferent duct absorptive cells: 97.1;Epididymal principal cells: 214.3;Leydig cells: 83.7;Loop of henle epithelial cells: 81.3;Lymphatic endothelial cells: 88.0;Papillary tip epithelial cells: 62.6;Peritubular myoid cells: 65.4;Renal collecting duct intercalated cells: 64.7;Renal collecting duct principal cells: 138.1;Renal connecting tubule cells: 151.3;Vascular endothelial cells: 54.8" "Cell type enhanced" "Detected in some" "lower rhombic lip: 26.3;splatter: 22.4" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 17.6" "Group enriched" "Detected in many" 10 "medulla oblongata: 18.6;pons: 12.0;spinal cord: 11.8;white matter: 9.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 9.3" "Minor Salivary Gland - Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells" "Region enriched" "Detected in single" 35 "pons and medulla: 3.5" "Group enriched" "Detected in some" 6 "medulla oblongata: 5.4;pons: 1.5;spinal cord: 4.1" "HPA051831, HPA063671" Supported "Nucleoplasm,Nuclear bodies" No NA "Cluster 22: Epididymis - Mixed function" "Cluster 43: Hindbrain - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 6 Nucleoplasm "Nuclear bodies" "HPA051831: , HPA063671: " "unprognostic (5.26e-3)" "unprognostic (8.38e-2)" "unprognostic (1.66e-2)" "unprognostic (1.59e-2)" "unprognostic (1.00e-1)" "unprognostic (5.68e-2)" "unprognostic (3.36e-3)" "unprognostic (1.04e-1)" "potential prognostic favorable (4.41e-4)" "potential prognostic unfavorable (6.98e-6)" "unprognostic (4.50e-1)" "unprognostic (3.95e-1)" "unprognostic (2.14e-3)" "unprognostic (4.44e-2)" "unprognostic (4.76e-2)" "unprognostic (3.63e-2)" HOXD4 "HOX4, HOX4B" ENSG00000170166 "Homeobox D4" P09016 2 176151550-176153226 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 28.8;epididymis: 26.4" "Cell type enhanced" "Detected in single" "Fallopian tube ciliated cells: 1.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 24.6" "Group enriched" "Detected in some" 24 "medulla oblongata: 22.8;pons: 11.2;spinal cord: 17.4;white matter: 15.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 14.3" "Minor Salivary Gland - Endothelial cells, Prostate - Endothelial cells" "Region enriched" "Detected in single" 46 "pons and medulla: 4.5" "Group enriched" "Detected in some" 4 "medulla oblongata: 7.2;spinal cord: 9.6" "HPA054383, HPA070349" Approved Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 43: Hindbrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 2 Nucleoplasm "Cell Junctions" "HPA054383: , HPA070349: " "unprognostic (3.15e-2)" "unprognostic (3.92e-1)" "potential prognostic favorable (3.79e-4)" "unprognostic (1.65e-2)" "unprognostic (1.42e-1)" "unprognostic (6.78e-2)" "unprognostic (6.03e-2)" "unprognostic (2.23e-2)" "unprognostic (1.51e-1)" "unprognostic (3.88e-3)" "unprognostic (1.28e-3)" "unprognostic (2.84e-2)" "unprognostic (4.31e-2)" "unprognostic (2.70e-3)" "unprognostic (5.58e-3)" "unprognostic (6.03e-2)" "unprognostic (1.55e-1)" "unprognostic (3.95e-1)" "unprognostic (3.97e-1)" "unprognostic (5.16e-1)" "unprognostic (2.81e-2)" "unprognostic (1.88e-1)" "unprognostic (1.13e-1)" HOXD8 "HOX4, HOX4E" ENSG00000175879 "Homeobox D8" P13378 2 176129694-176132695 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 94.1;kidney: 71.1" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 82.0;Early primary spermatocytes: 52.2;Early spermatids: 94.5;Epididymal efferent duct absorptive cells: 52.8;Epididymal efferent duct ciliated cells: 55.8;Epididymal principal cells: 143.1;Fallopian tube ciliated cells: 39.5;Late primary spermatocytes: 166.0;Leydig cells: 39.4;Lymphatic endothelial cells: 87.5;Peritubular myoid cells: 47.5;Renal connecting tubule cells: 47.0;Vascular endothelial cells: 35.9" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 40.2" "Group enriched" "Detected in some" 11 "medulla oblongata: 3.3;spinal cord: 8.6;white matter: 12.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 27.5" "Breast - Endothelial cells, Minor Salivary Gland - Endothelial cells, Prostate - Endothelial cells, Spleen - Endothelial cells, Stomach - Endothelial cells, Testis - Early spermatids" "Not detected" "Not detected" "Region enriched" "Detected in single" 71 "spinal cord: 45.9" NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 22: Non-specific - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 2 "unprognostic (1.45e-1)" "unprognostic (2.93e-1)" "unprognostic (2.56e-1)" "unprognostic (2.68e-1)" "unprognostic (5.12e-2)" "unprognostic (2.50e-3)" "unprognostic (4.88e-1)" "unprognostic (1.34e-2)" "unprognostic (2.51e-1)" "unprognostic (9.07e-2)" "validated prognostic favorable (1.81e-6)" "validated prognostic favorable (8.21e-5)" "unprognostic (3.40e-2)" "potential prognostic unfavorable (2.82e-4)" "unprognostic (3.19e-2)" "unprognostic (5.13e-2)" "unprognostic (3.34e-2)" "unprognostic (2.64e-2)" "unprognostic (7.85e-2)" "unprognostic (3.87e-1)" "unprognostic (4.84e-1)" "unprognostic (2.17e-1)" "potential prognostic unfavorable (1.34e-4)" "unprognostic (9.16e-2)" "unprognostic (4.46e-2)" "unprognostic (8.54e-3)" "unprognostic (1.97e-1)" "unprognostic (3.63e-3)" "unprognostic (1.53e-1)" HOXD9 "HOX4, HOX4C" ENSG00000128709 "Homeobox D9" P28356 2 176122719-176124937 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 41.1;endometrium 1: 59.3;kidney: 49.0" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 49.2;Epididymal principal cells: 39.6;Leydig cells: 25.9;Loop of henle epithelial cells: 19.6;Lymphatic endothelial cells: 44.1;Oocytes: 13.8;Papillary tip epithelial cells: 15.1;Peritubular myoid cells: 23.7;Renal collecting duct principal cells: 28.1;Renal connecting tubule cells: 47.4;Vascular endothelial cells: 30.4" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in some" 5 "medulla oblongata: 1.1;spinal cord: 1.2;white matter: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 23.4;Neuroblastoma: 22.6" "Thyroid gland - Fibroblasts" "Not detected" "Not detected" "Region enriched" "Detected in single" 105 "spinal cord: 10.5" HPA068683 Supported Nucleoplasm,Nucleoli NA NA "Cluster 75: Ovary - Mixed function" "Cluster 22: Non-specific - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "Nucleoplasm, Nucleoli" "HPA068683: " "unprognostic (2.65e-1)" "unprognostic (2.29e-1)" "unprognostic (1.50e-2)" "unprognostic (4.07e-1)" "unprognostic (1.80e-1)" "unprognostic (7.48e-2)" "unprognostic (4.30e-2)" "unprognostic (2.20e-2)" "unprognostic (6.92e-3)" "unprognostic (1.42e-1)" "unprognostic (7.55e-2)" "unprognostic (2.28e-3)" "unprognostic (5.99e-2)" "potential prognostic unfavorable (7.69e-6)" "unprognostic (6.12e-3)" "unprognostic (5.40e-3)" "unprognostic (5.36e-2)" "unprognostic (2.07e-1)" "unprognostic (6.09e-2)" "unprognostic (3.73e-2)" "unprognostic (1.32e-1)" "unprognostic (2.39e-2)" "unprognostic (3.83e-2)" "unprognostic (8.57e-2)" "unprognostic (3.85e-2)" "unprognostic (1.84e-1)" "unprognostic (6.94e-2)" "unprognostic (1.39e-1)" "unprognostic (1.76e-1)" "unprognostic (5.01e-2)" HP ENSG00000257017 Haptoglobin P00738 16 72054505-72061055 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Acute phase, Immunity" "Antibiotic, Antimicrobial, Antioxidant, Serine protease homolog" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 90 "liver: 55848.1" "Cell type enriched" "Detected in some" 12 "Hepatocytes: 65516.9" "Group enriched" "Detected in some" 5 "astrocyte: 2.3;Bergmann glia: 3.3" "Cancer enriched" "Detected in all" 53 "Liver Hepatocellular Carcinoma (TCGA): 14658.5" "Region enhanced" "Detected in all" "medulla oblongata: 56.4" "Group enriched" "Detected in many" 5 "classical monocyte: 49.5;eosinophil: 80.5" "Group enriched" "Detected in many" 7 "granulocytes: 80.5;monocytes: 49.5" "Group enriched" "Detected in some" 12 "Gastric cancer: 6.6;Leukemia: 4.1;liver cancer: 15.7" "Adipose visceral - Mesothelial cells, Kidney - Macrophages, Liver - Hepatocytes" "CAB003787, HPA047750, HPA066795" Enhanced Approved Vesicles "Secreted to blood" "Acute phase" NA NA 998000000000 260000000000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 53: Liver - Plasma proteins" "Cluster 12: Non-specific - Vasculature" "Cluster 18: Liver cancer - Metabolism" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 22 Vesicles "CAB003787: , HPA047750: , HPA066795: " "unprognostic (1.68e-1)" "unprognostic (4.25e-2)" "unprognostic (3.57e-3)" "unprognostic (3.20e-3)" "unprognostic (2.41e-1)" "unprognostic (1.69e-2)" "unprognostic (2.13e-3)" "unprognostic (4.18e-3)" "unprognostic (4.87e-2)" "unprognostic (1.07e-1)" "validated prognostic unfavorable (4.39e-9)" "validated prognostic unfavorable (6.87e-5)" "unprognostic (1.16e-2)" "unprognostic (1.56e-3)" "potential prognostic favorable (9.68e-5)" "unprognostic (3.98e-2)" "potential prognostic unfavorable (3.47e-4)" "unprognostic (1.77e-3)" "unprognostic (1.67e-1)" "unprognostic (1.09e-1)" "unprognostic (2.66e-1)" "unprognostic (2.27e-1)" "unprognostic (6.33e-2)" "unprognostic (1.94e-1)" "unprognostic (1.96e-1)" "unprognostic (1.89e-1)" "potential prognostic unfavorable (5.23e-4)" "unprognostic (1.32e-1)" "unprognostic (2.74e-1)" "unprognostic (8.82e-2)" HP1BP3 HP1-BP74 ENSG00000127483 "Heterochromatin protein 1 binding protein 3" Q5SSJ5 1 20740266-20787323 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028215, HPA054295" Supported Supported "Nuclear speckles" NA Yes 27000 "Cluster 45: Eosinophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 37: Non-specific - mRNA processing" "Cluster 27: Non-specific - Cell proliferation" 55 "Nuclear speckles" "HPA028215: , HPA054295: " "unprognostic (8.36e-3)" "unprognostic (1.22e-1)" "unprognostic (7.48e-2)" "unprognostic (4.96e-2)" "unprognostic (1.29e-1)" "unprognostic (6.73e-2)" "unprognostic (1.46e-1)" "unprognostic (9.36e-3)" "unprognostic (1.62e-3)" "unprognostic (1.20e-3)" "potential prognostic favorable (3.18e-5)" "unprognostic (3.60e-3)" "unprognostic (8.50e-2)" "validated prognostic unfavorable (8.74e-4)" "validated prognostic unfavorable (7.47e-4)" "unprognostic (6.45e-2)" "unprognostic (9.58e-2)" "unprognostic (2.67e-1)" "unprognostic (5.96e-2)" "unprognostic (1.47e-1)" "unprognostic (2.29e-1)" "unprognostic (1.23e-2)" "unprognostic (1.54e-1)" "unprognostic (9.59e-2)" "unprognostic (1.48e-1)" "potential prognostic favorable (5.01e-5)" "unprognostic (1.33e-1)" "unprognostic (2.48e-1)" "unprognostic (1.05e-1)" "unprognostic (1.03e-2)" "unprognostic (1.92e-1)" HPCA DYT2 ENSG00000121905 Hippocalcin P84074 1 32885994-32898441 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Disease variant, Dystonia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 55 "brain: 945.6" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 55.3;Brain inhibitory neurons: 91.2;Early spermatids: 181.2;Late spermatids: 160.5;Retinal amacrine cells: 36.7;Retinal bipolar cells: 138.3" "Cell type enhanced" "Detected in many" "hippocampal CA4: 294.8;medium spiny neuron: 170.3" "Cancer enriched" "Detected in some" 9 "Glioblastoma Multiforme (TCGA): 17.0" "Group enriched" "Detected in all" 5 "basal ganglia: 1014.1;cerebral cortex: 607.4;hippocampal formation: 625.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 6.4;Neuroblastoma: 4.7" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basal ganglia: 1759.8;hippocampal formation: 1320.6" "CAB012340, HPA043245" Enhanced NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 35 "CAB012340: , HPA043245: " "unprognostic (1.06e-1)" "unprognostic (7.38e-3)" "unprognostic (2.81e-1)" "unprognostic (2.81e-3)" "unprognostic (1.77e-1)" "potential prognostic favorable (8.41e-4)" "unprognostic (1.12e-1)" "unprognostic (1.66e-3)" "unprognostic (4.22e-2)" "unprognostic (1.34e-3)" "unprognostic (1.96e-1)" HPCAL1 "BDR1, HLP2, VILIP-3" ENSG00000115756 "Hippocalcin like 1" P37235 2 10302889-10427617 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "brain: 410.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 562.3;Goblet cells: 372.3;Neutrophils: 665.5;Paneth cells: 305.5;Somatotrophs: 394.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Lung - Alveolar cells type 1, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043245 Supported NA NA 370000 "Cluster 7: Non-specific - Innate immune response" "Cluster 71: Cerebellum - Nervous system development" "Cluster 1: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 54 "HPA043245: " "unprognostic (1.73e-1)" "unprognostic (6.78e-2)" "unprognostic (3.82e-2)" "unprognostic (1.64e-2)" "unprognostic (2.08e-1)" "unprognostic (4.24e-3)" "potential prognostic unfavorable (8.90e-5)" "unprognostic (2.00e-1)" "unprognostic (1.43e-1)" "unprognostic (6.38e-2)" "potential prognostic favorable (3.44e-4)" "unprognostic (1.27e-1)" "unprognostic (4.47e-2)" "potential prognostic unfavorable (4.92e-4)" "unprognostic (1.48e-3)" "unprognostic (2.21e-2)" "unprognostic (1.38e-1)" "unprognostic (1.21e-2)" "unprognostic (1.52e-1)" "unprognostic (2.07e-1)" "unprognostic (1.81e-1)" "unprognostic (4.93e-2)" "unprognostic (3.72e-3)" "unprognostic (2.31e-1)" "unprognostic (6.76e-3)" "unprognostic (1.53e-2)" "unprognostic (2.37e-2)" "unprognostic (3.26e-1)" "unprognostic (2.10e-1)" "unprognostic (2.34e-1)" "unprognostic (7.02e-2)" HPCAL4 "DKFZp761G122, HLP4" ENSG00000116983 "Hippocalcin like 4" Q9UM19 1 39678648-39691485 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "brain: 122.5" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 21.3;Bergmann glia: 9.6;Brain excitatory neurons: 40.2;Brain inhibitory neurons: 41.1;Ependymal cells: 9.3;Other brain neurons: 31.3;Retinal amacrine cells: 26.8;Retinal bipolar cells: 24.3" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in some" 9 "Glioblastoma Multiforme (TCGA): 9.2;Thyroid Carcinoma (TCGA): 6.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory CD4 T-cell: 3.0;naive CD4 T-cell: 2.6" "Lineage enriched" "Detected in single" 30 "T-cells: 3.0" "Cancer enriched" "Detected in some" 5 "Neuroblastoma: 5.7" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Prostate - Fibroblasts, Skin - Hair cortex cells, Skin - Inner root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053808 Approved Cytosol NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 16 Cytosol "HPA053808: " "unprognostic (7.41e-2)" "unprognostic (5.09e-3)" "unprognostic (1.21e-1)" "unprognostic (5.47e-2)" HPD "4-HPPD, 4HPPD, GLOD3, PPD" ENSG00000158104 "4-hydroxyphenylpyruvate dioxygenase" P32754 12 121839527-121863596 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Phenylalanine catabolism, Tyrosine catabolism" "Dioxygenase, Oxidoreductase" "Disease variant, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 2365.4" "Cell type enriched" "Detected in many" 7 "Hepatocytes: 1643.3" "Cell type enriched" "Detected in many" 10 "choroid plexus epithelial cell: 130.4" "Cancer enriched" "Detected in many" 52 "Liver Hepatocellular Carcinoma (TCGA): 1099.3" "Region enriched" "Detected in many" 16 "choroid plexus: 242.9" "Immune cell enhanced" "Detected in some" "eosinophil: 7.9" "Group enriched" "Detected in many" 4 "dendritic cells: 3.8;granulocytes: 7.9" "Group enriched" "Detected in many" 5 "liver cancer: 40.7;lung cancer: 14.8;Rhabdoid: 39.7" "Breast - Fibroblasts, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Smooth muscle cells, Spleen - Fibroblasts_2, Stomach - Fibroblasts, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038321, HPA038322" Enhanced Uncertain "Nuclear speckles" NA NA 15000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 36: Choroid plexus - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 93: Hepatocytes - Bile production & excretion" 3 "Nuclear speckles" "HPA038321: , HPA038322: " "unprognostic (8.08e-2)" "unprognostic (8.33e-3)" "unprognostic (9.12e-2)" "unprognostic (2.49e-2)" "potential prognostic unfavorable (5.43e-8)" "unprognostic (2.13e-1)" "unprognostic (7.02e-2)" "unprognostic (1.77e-1)" "unprognostic (2.37e-1)" "unprognostic (1.20e-2)" "unprognostic (2.15e-3)" "unprognostic (1.06e-1)" "unprognostic (1.21e-2)" "unprognostic (1.21e-3)" "unprognostic (1.44e-2)" "unprognostic (4.29e-1)" "potential prognostic unfavorable (4.25e-4)" HPDL "4-HPPD-L, GLOXD1, MGC15668" ENSG00000186603 "4-hydroxyphenylpyruvate dioxygenase like" Q96IR7 1 45326895-45328710 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Disease variant, Hereditary spastic paraplegia, Intellectual disability, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.0" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 42.4;Enteric stem cells: 19.0;Enteric transient amplifying cells: 14.9;Erythrocyte progenitors: 11.4;Esophageal basal cells: 8.0;Gastric progenitor cells: 23.1;Megakaryocyte progenitors: 13.2;Megakaryocyte-Erythroid progenitors: 9.1;Megakaryocytes: 12.4;Migrating cytotrophoblasts: 34.4;Paneth cells: 11.6" "Cell type enhanced" "Detected in some" "astrocyte: 3.0;upper rhombic lip: 2.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Spleen - Mitotic cells (Spleen)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA031997, HPA057346" Supported Nucleoplasm,Mitochondria No NA "Cluster 24: Non-specific - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 34: Testis cancer - Unknown function" "Cluster 63: Cytotrophoblasts - Basic cellular functions" Mitochondria Nucleoplasm "HPA031997: , HPA057346: " "unprognostic (2.10e-2)" "unprognostic (2.51e-3)" "unprognostic (1.29e-1)" "unprognostic (8.84e-2)" "unprognostic (1.69e-1)" "unprognostic (6.30e-2)" "unprognostic (1.45e-1)" "unprognostic (5.90e-2)" "unprognostic (1.21e-1)" "unprognostic (1.36e-1)" "unprognostic (2.63e-3)" "unprognostic (1.79e-2)" "potential prognostic unfavorable (7.76e-4)" "unprognostic (1.02e-1)" "unprognostic (1.27e-1)" "unprognostic (2.00e-1)" "unprognostic (1.33e-1)" "unprognostic (6.21e-2)" "unprognostic (1.14e-1)" "unprognostic (3.32e-2)" "unprognostic (2.69e-1)" HPF1 "C4orf27, FLJ20534" ENSG00000056050 "Histone PARylation factor 1" Q9NWY4 4 169729470-169757944 "Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 303.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043467 Uncertain Approved Approved "Microtubules,Cytokinetic bridge,Cytosol" Yes No "Cluster 3: Non-specific - Nuclear processes" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 97: Non-specific - Cellular respiration" 7 Cytosol "Microtubules, Cytokinetic bridge" "HPA043467: " "unprognostic (4.32e-2)" "unprognostic (3.50e-3)" "unprognostic (1.70e-2)" "unprognostic (2.75e-2)" "unprognostic (2.01e-3)" "unprognostic (3.78e-3)" "unprognostic (6.23e-2)" "unprognostic (3.31e-1)" "unprognostic (4.84e-2)" "potential prognostic favorable (1.36e-5)" "unprognostic (2.95e-2)" "unprognostic (3.73e-1)" "unprognostic (1.21e-3)" "potential prognostic unfavorable (2.37e-4)" "unprognostic (9.43e-2)" "unprognostic (8.35e-2)" "unprognostic (1.17e-1)" "unprognostic (2.71e-2)" "unprognostic (2.53e-1)" "unprognostic (1.55e-1)" "unprognostic (5.26e-2)" "unprognostic (3.71e-1)" "unprognostic (1.87e-2)" "unprognostic (3.49e-1)" "unprognostic (1.07e-2)" "unprognostic (1.32e-1)" "unprognostic (2.54e-1)" "unprognostic (3.76e-3)" "unprognostic (4.89e-2)" HPGD SDR36C1 ENSG00000164120 "15-hydroxyprostaglandin dehydrogenase" P15428 4 174490175-174523154 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Prostaglandin metabolism" Oxidoreductase "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 222.0;urinary bladder: 352.4" "Cell type enhanced" "Detected in many" "Enterocytes: 600.7;Esophageal apical cells: 2508.6;Extravillous trophoblasts: 1375.4;Foveolar cells: 1121.8;Mast cells: 1378.9;Neutrophils: 640.0;Prostatic club cells: 638.1;Prostatic hillock cells: 401.8;Urothelial cells: 1575.5" "Group enriched" "Detected in many" 4 "choroid plexus epithelial cell: 85.5;endothelial cell: 47.0" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 97.6" "Region enhanced" "Detected in many" "choroid plexus: 17.4" "Group enriched" "Detected in many" 5 "basophil: 123.8;T-reg: 45.1" "Group enriched" "Detected in many" 73 "granulocytes: 123.8;T-cells: 45.1" "Cancer enhanced" "Detected in many" "testis cancer: 111.7" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Keratinocyte (granular), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004919, HPA005679" Enhanced Supported Nucleoplasm,Cytosol No NA 12000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 36: Choroid plexus - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 69: Urothelial cells - Basic cellular functions" 4 Cytosol Nucleoplasm "HPA004919: , HPA005679: " "unprognostic (2.13e-1)" "unprognostic (8.70e-3)" "unprognostic (3.55e-1)" "unprognostic (2.22e-1)" "unprognostic (3.68e-2)" "unprognostic (1.01e-1)" "unprognostic (4.47e-1)" "unprognostic (4.01e-2)" "unprognostic (1.59e-1)" "potential prognostic favorable (9.77e-8)" "unprognostic (6.86e-3)" "unprognostic (5.76e-3)" "unprognostic (1.19e-1)" "unprognostic (5.71e-3)" "unprognostic (3.76e-1)" "unprognostic (3.10e-1)" "unprognostic (2.63e-1)" "unprognostic (2.77e-1)" "unprognostic (3.74e-2)" "unprognostic (1.07e-1)" "unprognostic (3.95e-3)" "unprognostic (6.02e-3)" "unprognostic (8.05e-3)" "unprognostic (2.18e-1)" "unprognostic (3.50e-1)" "unprognostic (6.74e-2)" "unprognostic (1.26e-1)" "unprognostic (2.01e-1)" "potential prognostic unfavorable (1.33e-5)" "unprognostic (4.72e-1)" HPGDS "GSTS, GSTS1, GSTS1-1, H-PGDS, PGD2, PGDS" ENSG00000163106 "Hematopoietic prostaglandin D synthase" O60760 4 94298535-94342876 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Isomerase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 17.6" "Group enriched" "Detected in some" 14 "Hofbauer cells: 1753.4;Mast cells: 1807.1;Tuft cells: 1175.9" "Cell type enriched" "Detected in some" 56 "central nervous system macrophage: 163.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 28 "basophil: 18.2" "Lineage enriched" "Detected in single" 28 "granulocytes: 18.2" "Cancer enriched" "Detected in single" 32 "Leukemia: 8.2" "Adrenal gland - Macrophages, Colon - Mast cells, Lung - Mast cells, Stomach - Fibroblasts" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA024035 Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA 160000 "Cluster 46: Basophils - Proteolysis" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 58: Mast cells - Allergic inflammatory responses" 5 "Vesicles, Cytosol" Nucleoplasm "HPA024035: " "unprognostic (1.77e-1)" "unprognostic (4.13e-2)" "unprognostic (3.79e-1)" "unprognostic (9.95e-3)" "unprognostic (1.70e-1)" "unprognostic (6.44e-2)" "potential prognostic favorable (6.35e-4)" "unprognostic (3.92e-2)" "unprognostic (2.85e-1)" "unprognostic (8.40e-2)" "potential prognostic favorable (4.76e-4)" "unprognostic (1.45e-1)" "unprognostic (9.97e-2)" "unprognostic (1.88e-1)" "unprognostic (2.24e-3)" "unprognostic (1.03e-2)" "unprognostic (8.81e-2)" "unprognostic (3.48e-2)" "unprognostic (2.12e-1)" "unprognostic (3.26e-1)" "unprognostic (4.92e-2)" "unprognostic (1.67e-2)" HPN TMPRSS1 ENSG00000105707 Hepsin P05981 19 35040506-35066573 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 197.5;liver: 849.7;pancreas: 263.1" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 245.2;Epididymal efferent duct absorptive cells: 233.9;Hepatocytes: 715.3;Loop of henle epithelial cells: 150.4;Pancreatic acinar cells: 152.6;Proximal tubule cells: 451.8" "Cell type enhanced" "Detected in many" "Bergmann glia: 25.3;oligodendrocyte: 60.7" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 316.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "liver cancer: 21.3;prostate cancer: 66.2" "Breast - Breast glandular cells, Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Lung - Alveolar cells type 2, Pituitary gland - Corticotropes, Prostate - Prostate glandular cells" "Low region specificity" "Detected in single" "Region enhanced" "Detected in some" "olfactory bulb: 3.1" HPA006804 Approved NA NA 24000000 "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 11: White matter - Signal transduction" "Cluster 60: Prostate cancer - Unknown function" "Cluster 88: Proximal tubular cells - Transmembrane transport" 4 "HPA006804: " "unprognostic (1.00e-1)" "unprognostic (2.91e-2)" "unprognostic (2.85e-1)" "unprognostic (3.30e-2)" "unprognostic (2.16e-2)" "unprognostic (7.73e-2)" "unprognostic (1.39e-1)" "unprognostic (2.19e-1)" "potential prognostic favorable (4.35e-5)" "unprognostic (1.20e-3)" "unprognostic (1.65e-3)" "unprognostic (1.42e-3)" "potential prognostic favorable (6.61e-4)" "unprognostic (4.93e-2)" "unprognostic (1.68e-3)" "unprognostic (4.99e-2)" "unprognostic (6.37e-2)" "unprognostic (1.33e-1)" "unprognostic (1.79e-1)" "unprognostic (1.83e-1)" "unprognostic (5.01e-2)" "unprognostic (3.92e-2)" "unprognostic (2.43e-1)" "unprognostic (5.84e-2)" "unprognostic (3.89e-2)" "unprognostic (1.50e-1)" "unprognostic (9.58e-2)" "unprognostic (1.80e-1)" "unprognostic (3.32e-1)" HPR ENSG00000261701 "Haptoglobin-related protein" P00739 16 72063148-72077246 "Enzymes, Plasma proteins, Predicted secreted proteins" "Serine protease homolog" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 758.6" "Cell type enriched" "Detected in some" 13 "Hepatocytes: 318.2" "Cell type enhanced" "Detected in some" "astrocyte: 3.9;Bergmann glia: 5.7" "Cancer enriched" "Detected in some" 47 "Liver Hepatocellular Carcinoma (TCGA): 430.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "liver cancer: 2.3;prostate cancer: 3.5" "Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes" HPA047750 Supported Approved Vesicles "Secreted to blood" Other NA NA 49000000000 83000000000 "Cluster 53: Liver - Plasma proteins" "Cluster 19: Astrocytes - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 93: Hepatocytes - Bile production & excretion" Vesicles "HPA047750: " "unprognostic (3.27e-1)" "unprognostic (3.70e-1)" "potential prognostic unfavorable (3.95e-6)" "unprognostic (1.99e-2)" "unprognostic (3.09e-3)" "potential prognostic favorable (8.74e-5)" "unprognostic (1.54e-1)" HPRT1 "HGPRT, HPRT" ENSG00000165704 "Hypoxanthine phosphoribosyltransferase 1" P00492 X 134460165-134520513 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Purine salvage" "Glycosyltransferase, Transferase" "Disease variant, FDA approved drug targets, Gout" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 300.3;Sertoli cells: 397.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006360, CAB012200" Enhanced Supported "Cytosol,Mid piece,Principal piece,End piece,Annulus" NA NA 5500000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 19 Cytosol "Mid piece, Principal piece, End piece, Annulus" "CAB012200: , HPA006360: " "unprognostic (3.25e-2)" "unprognostic (1.66e-1)" "unprognostic (6.03e-2)" "unprognostic (1.43e-1)" "unprognostic (4.59e-2)" "unprognostic (2.76e-2)" "unprognostic (2.87e-2)" "unprognostic (4.76e-2)" "potential prognostic unfavorable (1.36e-6)" "unprognostic (6.72e-2)" "unprognostic (1.73e-2)" "unprognostic (6.14e-3)" "potential prognostic unfavorable (7.00e-7)" "unprognostic (1.31e-2)" "potential prognostic unfavorable (1.40e-5)" "unprognostic (3.69e-3)" "unprognostic (2.27e-3)" "unprognostic (8.45e-3)" "unprognostic (5.99e-2)" "unprognostic (2.05e-1)" "unprognostic (2.83e-1)" "unprognostic (2.80e-2)" "unprognostic (1.12e-2)" "potential prognostic unfavorable (5.84e-4)" "unprognostic (5.68e-2)" "unprognostic (1.33e-1)" "unprognostic (1.46e-2)" "unprognostic (1.36e-1)" "unprognostic (1.22e-1)" "unprognostic (8.87e-2)" "unprognostic (1.21e-2)" HPS1 "BLOC3S1, HPS" ENSG00000107521 "HPS1 biogenesis of lysosomal organelles complex 3 subunit 1" Q92902 10 98410939-98446963 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Guanine-nucleotide releasing factor" "Albinism, Disease variant, Hermansky-Pudlak syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 27.7;Brain inhibitory neurons: 17.7;Choroid plexus epithelial cells: 23.2;Late spermatids: 26.3;Microglia: 45.2;Oligodendrocytes: 24.3;Parietal cells: 17.7;Proximal tubule cells: 20.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061260 Approved NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 102: Non-specific - Mixed function" 1 "HPA061260: " "unprognostic (2.79e-3)" "unprognostic (9.73e-2)" "unprognostic (7.93e-2)" "unprognostic (2.74e-1)" "unprognostic (6.29e-2)" "unprognostic (2.48e-1)" "unprognostic (4.35e-3)" "unprognostic (1.30e-3)" "unprognostic (3.54e-2)" "unprognostic (1.47e-1)" "unprognostic (4.10e-2)" "unprognostic (2.39e-1)" "unprognostic (2.39e-1)" "unprognostic (1.60e-2)" "unprognostic (1.09e-1)" "unprognostic (4.03e-2)" "unprognostic (6.28e-2)" "unprognostic (1.58e-1)" "unprognostic (4.86e-2)" "unprognostic (4.88e-3)" "unprognostic (4.49e-2)" "unprognostic (7.48e-2)" "unprognostic (9.58e-2)" "unprognostic (3.51e-3)" "unprognostic (1.18e-1)" "unprognostic (1.60e-2)" "unprognostic (8.32e-2)" "unprognostic (1.72e-1)" "unprognostic (1.29e-1)" "unprognostic (9.52e-2)" "unprognostic (3.38e-2)" HPS3 "BLOC2S1, SUTAL" ENSG00000163755 "HPS3 biogenesis of lysosomal organelles complex 2 subunit 1" Q969F9 3 149129638-149173732 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Albinism, Disease variant, Hermansky-Pudlak syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglia: 159.9" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 204.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046281, HPA052778" Approved Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 4 "Golgi apparatus, Plasma membrane" "HPA046281: , HPA052778: " "unprognostic (9.92e-2)" "unprognostic (1.37e-2)" "unprognostic (3.05e-2)" "unprognostic (3.00e-2)" "unprognostic (1.01e-1)" "unprognostic (2.20e-2)" "unprognostic (1.30e-1)" "unprognostic (5.15e-2)" "unprognostic (3.54e-1)" "unprognostic (1.17e-3)" "potential prognostic favorable (6.31e-5)" "unprognostic (3.30e-2)" "unprognostic (1.63e-1)" "unprognostic (2.16e-2)" "unprognostic (9.24e-2)" "potential prognostic unfavorable (8.79e-4)" "unprognostic (1.18e-2)" "unprognostic (2.25e-1)" "unprognostic (1.66e-1)" "unprognostic (2.54e-1)" "unprognostic (4.10e-2)" "unprognostic (7.97e-3)" "unprognostic (2.22e-3)" "unprognostic (2.25e-1)" "unprognostic (4.34e-2)" "unprognostic (5.26e-3)" "unprognostic (1.53e-1)" "unprognostic (1.19e-1)" "unprognostic (1.57e-1)" "unprognostic (9.26e-2)" "unprognostic (4.70e-2)" HPS4 "BLOC3S2, KIAA1667, LE" ENSG00000100099 "HPS4 biogenesis of lysosomal organelles complex 3 subunit 2" Q9NQG7 22 26443107-26483931 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Albinism, Hermansky-Pudlak syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Sertoli cells: 128.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003375, CAB033106, HPA050189" Approved Approved "Plasma membrane" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 2: Non-specific - Mixed function" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 6: Leukemia - Signal transduction" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 2 "Plasma membrane" "CAB033106: , HPA003375: , HPA050189: " "unprognostic (2.65e-1)" "unprognostic (2.77e-1)" "unprognostic (3.76e-2)" "unprognostic (6.32e-2)" "unprognostic (3.90e-3)" "unprognostic (3.56e-2)" "unprognostic (3.48e-2)" "potential prognostic favorable (6.93e-4)" "unprognostic (1.46e-1)" "unprognostic (8.13e-2)" "potential prognostic favorable (5.35e-8)" "unprognostic (3.03e-3)" "unprognostic (1.61e-1)" "unprognostic (7.39e-3)" "unprognostic (8.43e-2)" "unprognostic (1.72e-1)" "unprognostic (2.35e-2)" "unprognostic (1.59e-1)" "unprognostic (1.03e-3)" "unprognostic (3.40e-1)" "unprognostic (7.14e-2)" "unprognostic (1.97e-2)" "unprognostic (9.33e-3)" "unprognostic (8.38e-2)" "unprognostic (4.03e-3)" "unprognostic (5.71e-2)" "unprognostic (2.39e-1)" "unprognostic (1.26e-1)" "unprognostic (1.67e-1)" "unprognostic (4.34e-2)" "unprognostic (1.01e-1)" HPS5 "AIBP63, BLOC2S2, RU2" ENSG00000110756 "HPS5 biogenesis of lysosomal organelles complex 2 subunit 2" Q9UPZ3 11 18278668-18322198 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Albinism, Disease variant, Hermansky-Pudlak syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 32.8" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 49.8;Early spermatids: 39.9;Microglia: 38.0;Podocytes: 95.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 22.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" HPA077851 Approved Supported Cytosol NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 55: Non-specific - Transcription" "Cluster 69: Skin cancer - ECM organization" "Cluster 102: Non-specific - Mixed function" Cytosol "HPA077851: " "unprognostic (2.53e-1)" "unprognostic (1.55e-1)" "unprognostic (2.41e-1)" "unprognostic (4.43e-3)" "unprognostic (6.34e-2)" "unprognostic (1.84e-1)" "unprognostic (5.51e-2)" "unprognostic (4.68e-2)" "unprognostic (1.88e-1)" "potential prognostic unfavorable (8.65e-5)" "unprognostic (7.63e-3)" "unprognostic (3.32e-1)" "unprognostic (1.22e-1)" "unprognostic (1.26e-1)" "unprognostic (1.09e-1)" "unprognostic (4.21e-1)" "unprognostic (9.22e-3)" "unprognostic (1.98e-1)" "unprognostic (2.51e-1)" "unprognostic (8.31e-2)" "unprognostic (6.52e-2)" "unprognostic (1.54e-1)" "unprognostic (3.19e-3)" "unprognostic (3.63e-2)" "unprognostic (2.25e-2)" "unprognostic (5.92e-2)" "unprognostic (2.45e-1)" "unprognostic (1.86e-1)" "unprognostic (1.18e-1)" "unprognostic (1.59e-2)" "unprognostic (4.59e-2)" HPS6 "BLOC2S3, FLJ22501" ENSG00000166189 "HPS6 biogenesis of lysosomal organelles complex 2 subunit 3" Q86YV9 10 102065349-102068036 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Albinism, Hermansky-Pudlak syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Tuft cells: 23.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pancreas - Macrophages, Skin - Keratinocyte (granular), Spleen - Macrophages" "Low region specificity" "Detected in all" HPA040687 Approved Supported Vesicles,Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 17: Non-specific - RNA processing" 6 Cytosol Vesicles "HPA040687: " "unprognostic (2.44e-1)" "unprognostic (3.26e-2)" "unprognostic (1.57e-2)" "unprognostic (1.87e-2)" "unprognostic (2.00e-2)" "unprognostic (3.32e-2)" "unprognostic (1.46e-1)" "unprognostic (2.48e-3)" "unprognostic (2.22e-1)" "unprognostic (2.12e-1)" "potential prognostic favorable (8.34e-7)" "unprognostic (1.51e-1)" "unprognostic (4.30e-2)" "unprognostic (2.05e-2)" "unprognostic (2.32e-1)" "unprognostic (2.73e-2)" "unprognostic (1.36e-1)" "unprognostic (1.17e-1)" "unprognostic (7.95e-2)" "unprognostic (6.48e-2)" "unprognostic (7.49e-3)" "unprognostic (1.31e-1)" "unprognostic (1.27e-1)" "unprognostic (5.53e-2)" "unprognostic (3.42e-2)" "unprognostic (1.08e-1)" "unprognostic (6.55e-3)" "unprognostic (1.99e-2)" "unprognostic (2.07e-1)" "unprognostic (4.12e-1)" "unprognostic (3.92e-2)" HPSE "HPA, HPSE1, HSE1" ENSG00000173083 Heparanase Q9Y251 4 83292461-83335153 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Cell adhesion" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Epicardial cells: 88.7;Esophageal apical cells: 314.7;Kupffer cells: 63.5;monocytes: 58.0;Neutrophils: 150.3;Platelets: 242.0" "Cell type enriched" "Detected in some" 7 "central nervous system macrophage: 59.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 27.2;neutrophil: 18.6" "Group enriched" "Detected in many" 4 "granulocytes: 18.6;monocytes: 27.2" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Breast - Macrophages, Heart muscle - Macrophages" "Region enhanced" "Detected in some" "olfactory bulb: 3.7" "Low region specificity" "Detected in all" "CAB009813, HPA055344" Supported Nucleoplasm,Vesicles "Secreted to extracellular matrix" "Cell adhesion" No No 8900000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 30: White matter - Myelination" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 24: Neutrophils - Innate immunity signal integration" 5 Nucleoplasm Vesicles "CAB009813: , HPA055344: " "unprognostic (1.21e-3)" "unprognostic (1.49e-2)" "unprognostic (7.80e-2)" "unprognostic (1.68e-3)" "unprognostic (1.37e-1)" "unprognostic (2.95e-2)" "unprognostic (3.00e-1)" "unprognostic (4.48e-2)" "unprognostic (2.83e-1)" "unprognostic (4.26e-2)" "unprognostic (1.85e-2)" "unprognostic (2.77e-1)" "unprognostic (3.37e-1)" "unprognostic (9.39e-2)" "unprognostic (5.24e-3)" "unprognostic (1.06e-2)" "unprognostic (7.15e-2)" "unprognostic (8.66e-2)" "unprognostic (2.45e-1)" "unprognostic (2.85e-1)" "unprognostic (1.55e-2)" "unprognostic (2.84e-1)" "unprognostic (2.65e-1)" "unprognostic (1.30e-1)" "unprognostic (4.67e-2)" "unprognostic (8.85e-2)" "unprognostic (3.85e-2)" "unprognostic (1.18e-1)" "potential prognostic unfavorable (6.82e-4)" HPSE2 "HPA2, HPR2, UFS" ENSG00000172987 "Heparanase 2 (inactive)" Q8WWQ2 10 98457077-99235862 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.1;cervix: 29.6;vagina: 21.8" "Cell type enhanced" "Detected in many" "Adipocytes: 295.5;Astrocytes: 1765.3;Early primary spermatocytes: 386.7;Endometrial stromal cells: 759.1;Ependymal cells: 688.3;Melanocytes: 245.2;Pituicytes/FSCs: 232.7;Smooth muscle cells: 330.2;Undifferentiated spermatogonia: 190.4;Vascular smooth muscle cells: 189.1" "Group enriched" "Detected in all" 8 "astrocyte: 2414.9;ependymal cell: 844.1" "Cancer enhanced" "Detected in some" "Prostate Adenocarcinoma (TCGA): 6.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "Leukemia: 7.4;prostate cancer: 2.1" "Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA044603 Uncertain "Secreted to extracellular matrix" "No annotated function" NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 19: Astrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 28: Astrocytes - Homeostasis & neuron support" "HPA044603: " "unprognostic (1.59e-2)" "unprognostic (3.09e-2)" "unprognostic (1.51e-1)" "unprognostic (6.67e-3)" "unprognostic (4.27e-2)" "unprognostic (4.95e-2)" "unprognostic (2.39e-1)" "unprognostic (7.55e-2)" "unprognostic (9.74e-2)" "unprognostic (2.89e-1)" HPX ENSG00000110169 Hemopexin P02790 11 6431049-6442617 "Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Host-virus interaction, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 792 "liver: 4942.7" "Cell type enriched" "Detected in many" 82 "Hepatocytes: 6458.7" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in many" 69 "Liver Hepatocellular Carcinoma (TCGA): 1671.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 9.0" "Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB016725, HPA065318, HPA068847" Approved "Secreted to blood" Transport NA NA 425000000000 270000000000 "Cluster 53: Liver - Plasma proteins" "Cluster 15: Non-specific - Transcription" "Cluster 18: Liver cancer - Metabolism" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 13 "CAB016725: , HPA065318: , HPA068847: " "unprognostic (6.27e-2)" "unprognostic (2.34e-1)" "unprognostic (2.35e-1)" "potential prognostic unfavorable (3.61e-8)" "validated prognostic favorable (3.68e-4)" "validated prognostic favorable (1.46e-8)" "unprognostic (1.86e-3)" "potential prognostic unfavorable (5.22e-4)" "unprognostic (1.77e-2)" "unprognostic (2.51e-1)" "unprognostic (3.42e-1)" HR "ALUNC, AU" ENSG00000168453 "HR lysine demethylase and nuclear receptor corepressor" O43593 8 22114419-22133384 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Oxidoreductase" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 31.3;esophagus: 21.3;skin 1: 53.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 27.9;Colonocytes: 32.6;Enteric transient amplifying cells: 21.0;Esophageal apical cells: 50.4;Esophageal basal cells: 32.4;Esophageal suprabasal cells: 29.3;Melanocytes: 38.5;Ocular epithelial cells: 24.0;Retinal bipolar cells: 68.5;Retinal pigment epithelial cells: 46.9;Suprabasal keratinocytes: 29.3" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 22.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 36.5" "Adipose visceral - Adipocytes (Visceral), Minor Salivary Gland - Minor salivary gland basal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054888 Supported Nucleoplasm NA NA "Cluster 2: Non-specific - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 18 Nucleoplasm "HPA054888: " "unprognostic (8.22e-2)" "unprognostic (1.27e-1)" "unprognostic (1.66e-2)" "unprognostic (1.25e-1)" "unprognostic (2.82e-1)" "unprognostic (1.60e-1)" "unprognostic (5.85e-2)" "unprognostic (1.20e-2)" "unprognostic (1.92e-1)" "unprognostic (7.54e-2)" "unprognostic (1.04e-1)" "unprognostic (4.78e-2)" "unprognostic (9.37e-3)" "unprognostic (3.54e-1)" "unprognostic (2.22e-1)" "unprognostic (2.35e-1)" "unprognostic (2.16e-1)" "unprognostic (1.79e-1)" "unprognostic (1.30e-1)" "unprognostic (1.33e-2)" "unprognostic (1.30e-1)" "unprognostic (2.31e-1)" "unprognostic (1.63e-1)" HRAS HRAS1 ENSG00000174775 "HRas proto-oncogene, GTPase" P01112 11 532242-537321 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" Hydrolase "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 123.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 65.6;Breast myoepithelial cells: 81.8;Esophageal suprabasal cells: 57.1;Suprabasal keratinocytes: 77.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 4.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002015, HPA049830, HPA070222, HPA072761, CAB080330, CAB080331, CAB080332" Supported Supported "Nucleoplasm,Basal body,Cytosol" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 26: Keratinocytes - Keratinization" 250 Cytosol "Nucleoplasm, Basal body" "CAB002015: , CAB080330: , CAB080331: , CAB080332: , HPA049830: , HPA070222: , HPA072761: " "unprognostic (1.03e-2)" "unprognostic (4.14e-2)" "unprognostic (4.55e-1)" "potential prognostic favorable (1.08e-5)" "unprognostic (1.80e-1)" "unprognostic (2.14e-1)" "unprognostic (1.89e-2)" "unprognostic (2.11e-1)" "unprognostic (2.13e-1)" "unprognostic (9.59e-2)" "unprognostic (3.44e-2)" "unprognostic (3.77e-1)" "unprognostic (1.39e-1)" "validated prognostic unfavorable (5.53e-6)" "validated prognostic unfavorable (3.48e-4)" "unprognostic (1.72e-2)" "unprognostic (8.84e-2)" "unprognostic (1.42e-1)" "unprognostic (6.86e-2)" "unprognostic (3.80e-1)" "unprognostic (1.94e-1)" "unprognostic (1.12e-1)" "potential prognostic unfavorable (3.61e-4)" "unprognostic (2.31e-2)" "unprognostic (2.16e-1)" "unprognostic (2.36e-1)" "unprognostic (4.00e-1)" "unprognostic (2.33e-1)" "unprognostic (2.36e-1)" "unprognostic (3.93e-2)" "unprognostic (1.52e-1)" HRC MGC133236 ENSG00000130528 "Histidine rich calcium binding protein" P23327 19 49151198-49155396 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 26 "heart muscle: 692.1;skeletal muscle: 424.2;tongue: 228.2" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 50.1;Hepatic stellate cells: 19.4;Myonuclei: 74.9;Oocytes: 36.8;Pericytes: 39.3;Thymic myoid cells: 142.8;Vascular smooth muscle cells: 45.6" "Group enriched" "Detected in some" 13 "pericyte: 25.1;vascular associated smooth muscle cell: 21.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Myeloma: 7.7;Rhabdoid: 2.9;Sarcoma: 5.7" "Adrenal gland - Fibroblasts, Heart muscle - Cardiomyocytes, Kidney - Fibroblasts, Liver - Hepatic stellate cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA004833, HPA004834" Enhanced Supported "Endoplasmic reticulum,Mitochondria,Cytosol" "Intracellular and membrane" "No annotated function" NA NA 170000 "Cluster 41: Striated muscle - Muscle contraction" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 110: Mural cells - ECM organization" 2 "Endoplasmic reticulum" "Mitochondria, Cytosol" "HPA004833: , HPA004834: " "unprognostic (7.68e-2)" "unprognostic (5.50e-2)" "unprognostic (9.55e-3)" "unprognostic (2.97e-2)" "unprognostic (4.19e-1)" "unprognostic (1.37e-1)" "unprognostic (1.46e-2)" "unprognostic (2.62e-1)" "validated prognostic favorable (3.54e-4)" "validated prognostic favorable (3.47e-6)" "unprognostic (3.31e-3)" "unprognostic (9.09e-2)" "unprognostic (2.81e-2)" "unprognostic (1.37e-1)" "unprognostic (7.89e-2)" "unprognostic (1.25e-1)" "unprognostic (4.76e-2)" HRCT1 "LGLL338, PRO537, UNQ338" ENSG00000196196 "Histidine rich carboxyl terminus 1" Q6UXD1 9 35906202-35907136 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "adipose tissue: 28.5;blood vessel: 51.2" "Cell type enhanced" "Detected in many" "Colonocytes: 225.2;Cytotrophoblasts: 28.8;Enterocytes: 60.8;Goblet cells: 62.9;Lymphatic endothelial cells: 78.6;Salivary myoepithelial cells: 24.6;Vascular endothelial cells: 30.0" "Cell type enriched" "Detected in some" 5 "endothelial cell: 35.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 23.8" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA059221 Approved "Nucleoplasm,Nuclear membrane,Nuclear speckles" NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 47: Endothelial cells - Vasculature" "Cluster 72: Neuronal - Signal transduction" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" "Nuclear membrane" "Nucleoplasm, Nuclear speckles" "HPA059221: " "unprognostic (7.63e-2)" "unprognostic (1.35e-2)" "unprognostic (1.28e-1)" "unprognostic (4.43e-2)" "unprognostic (5.04e-2)" "unprognostic (1.10e-3)" "unprognostic (4.71e-2)" "unprognostic (7.84e-3)" "unprognostic (1.57e-1)" "potential prognostic unfavorable (7.65e-4)" "unprognostic (3.98e-3)" "unprognostic (3.17e-1)" "unprognostic (3.83e-3)" "potential prognostic unfavorable (1.97e-4)" "unprognostic (2.13e-1)" "unprognostic (2.80e-2)" "unprognostic (2.70e-3)" "unprognostic (1.04e-1)" "unprognostic (3.31e-1)" "unprognostic (3.79e-1)" "unprognostic (6.17e-3)" "unprognostic (3.43e-1)" "unprognostic (2.11e-1)" "unprognostic (2.46e-1)" "unprognostic (1.36e-1)" "unprognostic (4.53e-2)" "unprognostic (2.66e-1)" "unprognostic (4.18e-1)" "unprognostic (4.08e-1)" "unprognostic (2.82e-1)" HRG "HPRG, HRGP" ENSG00000113905 "Histidine rich glycoprotein" P04196 3 186660216-186678234 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Angiogenesis, Blood coagulation, Chemotaxis, Fibrinolysis, Hemostasis" Heparin-binding "Disease variant, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 173 "liver: 5081.0" "Cell type enriched" "Detected in some" 55 "Hepatocytes: 513.4" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 197 "Liver Hepatocellular Carcinoma (TCGA): 1355.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Ascending Loop of Henle cells, Liver - Hepatocytes, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA050269, HPA054598" Supported "Secreted to blood" "Blood coagulation" NA NA 120000000000 43000000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 18: Liver cancer - Metabolism" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 11 "HPA050269: , HPA054598: " "unprognostic (1.12e-1)" "unprognostic (9.74e-3)" "unprognostic (1.94e-3)" "validated prognostic favorable (3.35e-4)" "validated prognostic favorable (3.37e-5)" "unprognostic (3.41e-2)" HRH1 ENSG00000196639 "Histamine receptor H1" P35367 3 11137093-11263557 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 244.0;Endometrial luminal cells: 139.3;Endometrial secretory cells: 179.9;Enterocytes: 141.1;Epididymal basal cells: 161.2;Epididymal efferent duct ciliated cells: 169.1;Fallopian secretory cells: 218.7;Fallopian tube ciliated cells: 227.0;Hofbauer cells: 189.5;Kupffer cells: 163.0;Macrophages: 133.9;Ocular epithelial cells: 151.6;Papillary tip epithelial cells: 147.9;Urothelial cells: 269.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Kupffer cells, Minor Salivary Gland - Endothelial cells, Spleen - Macrophages, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029740 Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 51: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 1 "Plasma membrane" Cytosol "HPA029740: " "unprognostic (1.64e-1)" "unprognostic (1.81e-2)" "unprognostic (1.87e-1)" "unprognostic (4.47e-2)" "unprognostic (4.87e-2)" "unprognostic (8.40e-2)" "unprognostic (1.89e-2)" "unprognostic (1.07e-2)" "unprognostic (3.55e-2)" "unprognostic (1.74e-3)" "unprognostic (2.30e-1)" "unprognostic (2.80e-1)" "unprognostic (2.02e-1)" "unprognostic (2.39e-1)" "unprognostic (1.43e-3)" "potential prognostic unfavorable (1.54e-5)" "unprognostic (6.03e-2)" "unprognostic (8.71e-2)" "unprognostic (7.41e-3)" "unprognostic (1.81e-2)" "potential prognostic unfavorable (1.21e-4)" "unprognostic (7.38e-3)" "unprognostic (1.32e-1)" "unprognostic (2.02e-3)" "unprognostic (5.31e-2)" "unprognostic (2.04e-1)" "unprognostic (7.64e-2)" "unprognostic (1.66e-1)" "unprognostic (7.02e-2)" HRH2 ENSG00000113749 "Histamine receptor H2" P25021 5 175658030-175710756 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.7;heart muscle: 15.7" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 68.6;Breast lactating cells: 61.5;Microglia: 61.4;Monocyte progenitors: 130.0;monocytes: 102.1;Neutrophil progenitors: 149.0;Neutrophils: 601.2;Parietal cells: 160.9;pDCs: 53.7;Vascular smooth muscle cells: 90.3" "Cell type enhanced" "Detected in many" "medium spiny neuron: 176.5" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 22.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 106.4;neutrophil: 141.7" "Group enriched" "Detected in many" 5 "granulocytes: 141.7;monocytes: 40.9" "Cancer enhanced" "Detected in some" "Leukemia: 7.1;Myeloma: 3.5;skin cancer: 3.7" "Adrenal gland - Macrophages, Liver - Neutrophils, Lung - Neutrophils_2, Pituitary gland - Macrophages, Spleen - Neutrophils_2, Stomach - Parietal cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA013770 Approved NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 53: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" "HPA013770: " "unprognostic (2.74e-2)" "unprognostic (1.48e-1)" "unprognostic (3.71e-2)" "unprognostic (1.04e-1)" "unprognostic (4.47e-2)" "unprognostic (3.30e-3)" "unprognostic (1.88e-1)" "unprognostic (1.58e-1)" "unprognostic (1.41e-3)" "potential prognostic favorable (3.05e-5)" "unprognostic (4.16e-2)" "unprognostic (7.43e-2)" "unprognostic (3.57e-2)" "unprognostic (1.93e-2)" "unprognostic (4.60e-2)" "unprognostic (1.95e-1)" "unprognostic (8.92e-3)" "unprognostic (2.57e-2)" "unprognostic (3.27e-2)" "unprognostic (2.35e-2)" "unprognostic (1.56e-1)" "unprognostic (9.43e-2)" "unprognostic (3.20e-2)" "unprognostic (4.75e-2)" "unprognostic (1.24e-1)" HRH3 GPCR97 ENSG00000101180 "Histamine receptor H3" Q9Y5N1 20 62214960-62220278 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 28 "brain: 51.9" "Cell type enhanced" "Detected in some" "Bergmann glia: 4.3;Brain excitatory neurons: 11.1;Brain inhibitory neurons: 44.6;Other brain neurons: 30.1;Retinal amacrine cells: 7.6;Retinal ganglion cells: 15.5" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 122.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "lung cancer: 5.0;Neuroblastoma: 9.3" "Adrenal gland - Adrenal medulla cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 109: Neurons - Neuronal signaling" 1 HRH4 "AXOR35, GPCR105, GPRv53, H4R, HH4R" ENSG00000134489 "Histamine receptor H4" Q9H3N8 18 24460637-24479961 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 4.1;Early spermatids: 3.1;Hematopoietic stem cells: 3.4;Hepatic stellate cells: 6.5;Late primary spermatocytes: 3.5;Mast cells: 9.5;Neutrophil progenitors: 4.6;Retinal ganglion cells: 3.9;Retinal horizontal cells: 4.0;Retinal pigment epithelial cells: 8.5" "Low cell type specificity" "Detected in some" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 123 "basophil: 212.9;eosinophil: 61.3" "Lineage enriched" "Detected in many" 191 "granulocytes: 212.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA035009 Uncertain NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 48: Non-specific - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 58: Mast cells - Allergic inflammatory responses" "HPA035009: " "unprognostic (1.80e-2)" HRK DP5 ENSG00000135116 "Harakiri, BCL2 interacting protein" O00198 12 116856144-116881441 "Essential proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 7.6;choroid plexus: 3.2;lymphoid tissue: 3.2;pituitary gland: 2.6;thyroid gland: 3.6" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 74.5;Choroid plexus epithelial cells: 41.0;Corticotrophs: 21.6;Ependymal cells: 35.7;Epididymal efferent duct ciliated cells: 44.9;Fallopian tube ciliated cells: 24.6;Lactotrophs: 28.2;Ocular epithelial cells: 24.6;Respiratory ciliated cells: 28.9;Salivary duct cells: 42.3;Somatotrophs: 99.9;Thyrotrophs: 37.8" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 5.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 30 "eosinophil: 1.3;memory B-cell: 3.7;naive B-cell: 3.9" "Group enriched" "Detected in many" 27 "B-cells: 3.9;granulocytes: 1.3" "Cancer enhanced" "Detected in many" "lymphoma: 9.1" "Adrenal gland - Adrenal medulla cells, Lung - Respiratory ciliated cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" CAB025973 Uncertain NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 78: Brain - Neuronal signaling" "Cluster 29: Forebrain - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 3 "CAB025973: " "unprognostic (1.19e-1)" "unprognostic (9.02e-3)" "unprognostic (2.84e-1)" "unprognostic (4.31e-3)" "unprognostic (2.47e-1)" "unprognostic (2.03e-1)" "unprognostic (1.05e-2)" "unprognostic (3.37e-2)" "unprognostic (1.26e-1)" "unprognostic (6.95e-2)" "unprognostic (5.00e-1)" HRNR "FLG3, S100A16, S100a18" ENSG00000197915 Hornerin Q86YZ3 1 152212076-152224193 "Plasma proteins, Predicted intracellular proteins" Keratinization "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Adipocytes: 5.2;Cardiomyocytes: 15.5;Epicardial cells: 25.0;Fibro-adipogenic progenitors: 5.3;Retinal ganglion cells: 3.9" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in single" "Skin Cutaneous Melanoma (TCGA): 2.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 3.0" "Not detected" "Not detected" HPA031469 Uncertain Uncertain Mitochondria No No 660000000 "Cluster 49: Hindbrain - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 10 Mitochondria "HPA031469: " "unprognostic (1.28e-1)" HROB "C17orf53, MCM8IP, MGC3130" ENSG00000125319 "Homologous recombination factor with OB-fold" Q8N3J3 17 44141906-44162476 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, DNA synthesis" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 8.8;testis: 10.7" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 16.7;Early primary spermatocytes: 14.7;Epicardial cells: 25.0;Esophageal basal cells: 13.2;Extravillous trophoblasts: 15.3;Late spermatids: 14.5;Neutrophils: 12.0;Oocytes: 36.8;Respiratory deuterosomal cells: 12.4;Undifferentiated spermatogonia: 23.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA023004, HPA023393, HPA024430" Uncertain Approved Nucleoplasm,Cytosol NA Yes "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" 5 "Nucleoplasm, Cytosol" "HPA023004: , HPA023393: , HPA024430: " "unprognostic (3.35e-3)" "unprognostic (2.73e-1)" "unprognostic (1.94e-1)" "unprognostic (2.12e-2)" "unprognostic (2.49e-1)" "unprognostic (7.84e-2)" "unprognostic (5.83e-3)" "unprognostic (1.97e-1)" "validated prognostic unfavorable (5.77e-5)" "validated prognostic unfavorable (8.81e-4)" "potential prognostic unfavorable (2.24e-8)" "potential prognostic unfavorable (3.75e-4)" "validated prognostic unfavorable (6.97e-5)" "validated prognostic unfavorable (2.26e-4)" "unprognostic (4.36e-2)" "unprognostic (1.10e-3)" "unprognostic (1.49e-1)" "unprognostic (1.19e-1)" "validated prognostic unfavorable (2.43e-5)" "validated prognostic unfavorable (1.42e-4)" "unprognostic (1.19e-2)" "unprognostic (1.17e-2)" "unprognostic (9.58e-2)" "unprognostic (1.39e-2)" "unprognostic (3.70e-2)" "unprognostic (8.82e-3)" HRURF U2HR ENSG00000288677 "HR upstream open reading frame" P0DUH7 8 22130458-22131010 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Translation regulation" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 6: Non-specific - Immune response" "Cluster 27: Breast cancer - Unknown function" HS1BP3 HS1-BP3,FLJ14249 ENSG00000118960 "HCLS1 binding protein 3" Q53T59 2 20560448-20651130 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 73.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035050 Approved Approved Nucleoli,Cytosol No No 21000 "Cluster 7: Non-specific - Innate immune response" "Cluster 76: Non-specific - Metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 12 Nucleoli Cytosol "HPA035050: " "unprognostic (2.01e-2)" "unprognostic (1.89e-2)" "unprognostic (1.42e-1)" "unprognostic (2.20e-2)" "unprognostic (1.11e-1)" "unprognostic (3.47e-2)" "unprognostic (2.45e-2)" "unprognostic (8.61e-2)" "unprognostic (2.03e-2)" "unprognostic (1.66e-1)" "potential prognostic favorable (4.61e-11)" "unprognostic (2.17e-1)" "unprognostic (1.75e-2)" "unprognostic (1.98e-3)" "unprognostic (6.97e-3)" "unprognostic (8.18e-2)" "unprognostic (1.77e-1)" "unprognostic (2.98e-1)" "unprognostic (1.58e-1)" "unprognostic (7.70e-2)" "unprognostic (3.86e-1)" "unprognostic (2.69e-1)" "unprognostic (3.19e-2)" "unprognostic (3.57e-1)" "unprognostic (1.91e-1)" "unprognostic (1.97e-3)" "unprognostic (2.61e-1)" "unprognostic (1.22e-1)" "unprognostic (1.37e-1)" "unprognostic (4.78e-2)" "unprognostic (2.82e-1)" HS2ST1 KIAA0448 ENSG00000153936 "Heparan sulfate 2-O-sulfotransferase 1" Q7LGA3 1 86914635-87109982 "Disease related genes, Metabolic proteins, Predicted intracellular proteins" Transferase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 315.9;Astrocytes: 241.8;Choroid plexus epithelial cells: 279.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043069, HPA043603, HPA075001" Supported Approved Mitochondria No No "Cluster 34: B-cells - Unknown function" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 11 Mitochondria "HPA043069: , HPA043603: , HPA075001: " "unprognostic (2.12e-2)" "unprognostic (1.17e-1)" "unprognostic (3.27e-1)" "unprognostic (3.15e-1)" "unprognostic (1.01e-3)" "unprognostic (1.12e-1)" "unprognostic (2.61e-1)" "potential prognostic unfavorable (9.17e-4)" "unprognostic (5.05e-2)" "potential prognostic unfavorable (3.78e-4)" "potential prognostic favorable (4.65e-7)" "unprognostic (3.84e-3)" "unprognostic (7.14e-2)" "unprognostic (7.71e-3)" "unprognostic (1.31e-2)" "unprognostic (1.35e-2)" "unprognostic (3.51e-2)" "unprognostic (2.12e-1)" "unprognostic (2.45e-1)" "unprognostic (2.44e-1)" "unprognostic (6.14e-3)" "potential prognostic unfavorable (5.96e-4)" "unprognostic (1.36e-3)" "unprognostic (3.13e-1)" "unprognostic (1.94e-1)" "unprognostic (2.44e-2)" "unprognostic (2.09e-2)" "unprognostic (4.79e-2)" "unprognostic (2.91e-1)" "unprognostic (1.77e-1)" "unprognostic (1.45e-1)" HS3ST1 3OST1 ENSG00000002587 "Heparan sulfate-glucosamine 3-sulfotransferase 1" O14792 4 11393150-11429564 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 29.3" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 378.6;Esophageal apical cells: 507.6;Esophageal suprabasal cells: 183.7;Granulosa cells: 156.5;Ocular epithelial cells: 412.5;Ovarian stromal cells: 244.8;Respiratory secretory cells: 271.5;Urothelial cells: 544.0" "Cell type enhanced" "Detected in many" "upper rhombic lip: 122.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 36 "memory B-cell: 15.0;naive B-cell: 26.7;plasmacytoid DC: 42.5" "Group enriched" "Detected in many" 110 "B-cells: 26.7;dendritic cells: 42.5" "Cancer enhanced" "Detected in many" "pancreatic cancer: 29.8" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002237 Approved Approved Vesicles "Intracellular and membrane" Enzyme NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 35: Non-specific - DNA binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 28 Vesicles "HPA002237: " "unprognostic (7.97e-3)" "unprognostic (1.76e-2)" "unprognostic (6.79e-2)" "unprognostic (2.38e-2)" "unprognostic (1.83e-2)" "unprognostic (3.09e-1)" "unprognostic (1.05e-1)" "unprognostic (2.44e-2)" "unprognostic (1.38e-2)" "unprognostic (2.29e-1)" "potential prognostic favorable (5.16e-6)" "unprognostic (2.73e-1)" "unprognostic (5.41e-2)" "unprognostic (6.70e-2)" "unprognostic (2.31e-1)" "unprognostic (6.40e-2)" "unprognostic (9.13e-2)" "unprognostic (2.28e-1)" "unprognostic (1.21e-1)" "unprognostic (2.27e-1)" "unprognostic (3.83e-2)" "unprognostic (2.37e-2)" "unprognostic (5.88e-2)" "unprognostic (3.54e-2)" "unprognostic (2.92e-2)" "unprognostic (1.90e-2)" "unprognostic (1.86e-2)" "unprognostic (1.76e-1)" "unprognostic (8.27e-2)" "unprognostic (2.82e-2)" HS3ST2 3OST2 ENSG00000122254 "Heparan sulfate-glucosamine 3-sulfotransferase 2" Q9Y278 16 22814162-22916338 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 7.2;brain: 19.8" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 51.2;Hofbauer cells: 84.6;Lymphatic endothelial cells: 214.1;Macrophages: 251.9;Pericytes: 59.4;Retinal bipolar cells: 114.7;Retinal ganglion cells: 46.4;Vascular endothelial cells: 99.2;Vascular smooth muscle cells: 156.4" "Cell type enhanced" "Detected in many" "deep-layer corticothalamic and 6b: 296.1;deep-layer intratelencephalic: 225.6;midbrain-derived inhibitory: 229.3" "Cancer enhanced" "Detected in some" "Kidney Renal Papillary Cell Carcinoma (TCGA): 4.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "Bone cancer: 4.0;Neuroblastoma: 2.6;thyroid cancer: 1.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA017736 Approved NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" "HPA017736: " "unprognostic (8.32e-2)" "potential prognostic unfavorable (5.09e-4)" "unprognostic (1.26e-1)" "unprognostic (1.09e-3)" "unprognostic (3.68e-2)" "unprognostic (1.10e-3)" "unprognostic (1.13e-3)" "unprognostic (1.86e-3)" "unprognostic (3.97e-2)" "unprognostic (1.86e-1)" "unprognostic (5.14e-1)" "unprognostic (5.60e-3)" HS3ST3A1 "30ST3A1, 3OST3A1" ENSG00000153976 "Heparan sulfate-glucosamine 3-sulfotransferase 3A1" Q9Y663 17 13494032-13601929 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 8.0" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 53.8;Choroid plexus epithelial cells: 261.8;Esophageal apical cells: 58.8;Esophageal suprabasal cells: 95.4;Leydig cells: 116.5;Ovarian stromal cells: 70.0;Pituitary stem cells: 79.3;Podocytes: 119.0;Retinal horizontal cells: 601.0;Schwann cells: 55.6" "Cell type enriched" "Detected in many" 7 "choroid plexus epithelial cell: 137.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "T-reg: 2.2" "Group enriched" "Detected in many" 5 "dendritic cells: 1.7;T-cells: 2.2" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Colon - Enteric glia cells, Prostate - Fibroblasts" "Region enhanced" "Detected in many" "olfactory bulb: 5.0" "Region enhanced" "Detected in many" "olfactory bulb: 5.3" "HPA062518, HPA071530" Uncertain Approved Microtubules NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 5: Spleen - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 101: Choroid plexus epithelial cells - Ion transport" Microtubules "HPA062518: , HPA071530: " "unprognostic (3.21e-1)" "unprognostic (1.20e-1)" "unprognostic (2.73e-1)" "unprognostic (1.00e-2)" "unprognostic (2.52e-2)" "unprognostic (3.82e-1)" "unprognostic (8.76e-3)" "potential prognostic unfavorable (2.94e-4)" "unprognostic (1.78e-1)" "unprognostic (2.99e-1)" "potential prognostic unfavorable (2.25e-5)" "unprognostic (2.01e-2)" "unprognostic (6.22e-3)" "unprognostic (7.61e-2)" "unprognostic (7.15e-2)" "unprognostic (3.96e-3)" "unprognostic (8.19e-3)" "unprognostic (4.68e-2)" "unprognostic (1.13e-1)" "unprognostic (6.69e-2)" "unprognostic (3.17e-1)" "unprognostic (2.07e-1)" "unprognostic (1.39e-2)" "unprognostic (1.83e-2)" "unprognostic (6.31e-2)" "unprognostic (2.01e-2)" HS3ST3B1 "30ST3B1, 3OST3B1" ENSG00000125430 "Heparan sulfate-glucosamine 3-sulfotransferase 3B1" Q9Y662 17 14301081-14349404 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 26.6;retina: 10.7" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 171.8;Hepatocytes: 61.1;Lacrimal acinar cells: 106.0;Neutrophil progenitors: 115.3;Neutrophils: 331.2;pDCs: 178.0;Podocytes: 109.2;Retinal horizontal cells: 78.1;Rod photoreceptor cells: 89.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 35.1" "Group enriched" "Detected in many" 5 "dendritic cells: 35.1;T-cells: 26.2" "Cancer enhanced" "Detected in many" "cervical cancer: 8.8" "Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA064126 Approved Vesicles NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 43: Hindbrain - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 29: Neutrophils - Innate immune cellular maintenance" Vesicles "HPA064126: " "unprognostic (4.26e-2)" "unprognostic (3.56e-1)" "unprognostic (2.38e-1)" "unprognostic (1.98e-1)" "unprognostic (4.04e-2)" "unprognostic (3.01e-3)" "potential prognostic unfavorable (3.20e-6)" "unprognostic (1.36e-1)" "potential prognostic favorable (3.58e-4)" "unprognostic (2.95e-2)" "unprognostic (8.93e-2)" "unprognostic (2.34e-2)" "unprognostic (2.21e-1)" "unprognostic (7.26e-2)" "unprognostic (8.66e-2)" "unprognostic (1.82e-1)" "unprognostic (1.62e-1)" "unprognostic (4.93e-1)" "unprognostic (1.25e-2)" "unprognostic (2.71e-1)" "unprognostic (2.62e-1)" "unprognostic (1.91e-2)" "unprognostic (8.79e-2)" "unprognostic (2.31e-1)" HS3ST4 3OST4 ENSG00000182601 "Heparan sulfate-glucosamine 3-sulfotransferase 4" Q9Y661 16 25691959-26137685 "Enzymes, Metabolic proteins, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 16.7" "Group enriched" "Detected in many" 5 "Microglia: 1017.5;Retinal bipolar cells: 295.3" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 1223.5;deep-layer corticothalamic and 6b: 1379.3;deep-layer near-projecting: 914.5" "Cancer enhanced" "Detected in some" "Prostate Adenocarcinoma (TCGA): 2.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 27 "Bone cancer: 24.1" "Breast - Breast glandular cells (progenitors), Colon - Colon enteroendocrine cells, Skin - Eccrine sweat gland cells, Stomach - Chief cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 24: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" "unprognostic (7.99e-2)" "unprognostic (1.34e-2)" "unprognostic (2.23e-1)" "unprognostic (1.68e-1)" "unprognostic (1.26e-2)" HS3ST5 3-OST-5 ENSG00000249853 "Heparan sulfate-glucosamine 3-sulfotransferase 5" Q8IZT8 6 114055596-114343023 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.9;skeletal muscle: 3.0;urinary bladder: 2.1" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 314.6;Cone photoreceptor cells: 308.4;Myonuclei: 351.0;Myosatellite cells: 389.6;Neutrophil progenitors: 209.3;Oligodendrocytes: 676.4;Other brain neurons: 131.9;Prostatic club cells: 107.9;Renal collecting duct principal cells: 341.7;Retinal ganglion cells: 150.6;Urothelial cells: 260.7" "Cell type enhanced" "Detected in all" "medium spiny neuron: 705.6;oligodendrocyte: 934.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 2.4" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Lung - Alveolar cells type 1, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA021823, HPA064677" Approved NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 18: Non-specific - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 55: Myocytes - Oxidative muscle function" "HPA021823: , HPA064677: " "unprognostic (3.94e-1)" HS3ST6 HS3ST5 ENSG00000162040 "Heparan sulfate-glucosamine 3-sulfotransferase 6" Q96QI5 16 1911475-1918415 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "skin 1: 75.2" "Cell type enriched" "Detected in some" 5 "Papillary tip epithelial cells: 10.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder Urothelial Carcinoma (TCGA): 5.6;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 4.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "Gallbladder cancer: 2.4" "Adipose visceral - Mesothelial cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Urothelial cells, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 27: Breast cancer - Unknown function" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" "unprognostic (4.16e-2)" "unprognostic (6.62e-2)" "potential prognostic favorable (3.01e-4)" "unprognostic (1.15e-2)" "unprognostic (1.16e-1)" "unprognostic (2.17e-1)" "unprognostic (3.49e-3)" HS6ST1 HS6ST ENSG00000136720 "Heparan sulfate 6-O-sulfotransferase 1" O60243 2 128236716-128318868 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Transferase "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 159.4;Mast cells: 213.3;Renal collecting duct principal cells: 242.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044586 Approved Nucleoplasm NA NA 260000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 58: Mast cells - Allergic inflammatory responses" 6 Nucleoplasm "HPA044586: " "unprognostic (2.45e-1)" "unprognostic (6.34e-2)" "unprognostic (2.47e-1)" "unprognostic (3.37e-1)" "unprognostic (3.72e-1)" "unprognostic (2.76e-1)" "unprognostic (4.63e-2)" "unprognostic (6.50e-2)" "unprognostic (3.63e-1)" "unprognostic (2.20e-1)" "potential prognostic favorable (7.03e-5)" "unprognostic (3.02e-2)" "unprognostic (5.18e-2)" "unprognostic (2.39e-2)" "unprognostic (2.86e-3)" "unprognostic (1.27e-2)" "unprognostic (5.15e-2)" "unprognostic (6.64e-2)" "unprognostic (8.58e-2)" "unprognostic (9.68e-2)" "unprognostic (3.75e-1)" "unprognostic (1.62e-1)" "unprognostic (1.97e-1)" "unprognostic (2.19e-1)" "unprognostic (3.46e-1)" "unprognostic (8.60e-3)" "unprognostic (1.77e-1)" "unprognostic (5.27e-2)" "unprognostic (1.66e-1)" "unprognostic (7.04e-3)" "unprognostic (2.73e-1)" HS6ST2 HS6ST-2 ENSG00000171004 "Heparan sulfate 6-O-sulfotransferase 2" Q96MM7 X 132626015-132961395 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Transferase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 13.3;kidney: 14.8;ovary: 15.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 278.9;Distal convoluted tubule cells: 414.0;Esophageal suprabasal cells: 154.9;Leydig cells: 491.9;Loop of henle epithelial cells: 223.8;Myosatellite cells: 112.4;Oligodendrocyte progenitor cells: 130.0;Ovarian stromal cells: 113.0;Peritubular myoid cells: 163.0;Pituicytes/FSCs: 237.3;Syncytiotrophoblasts: 134.8;Urothelial cells: 146.8" "Cell type enhanced" "Detected in all" "eccentric medium spiny neuron: 275.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Ascending Loop of Henle cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA034625 Uncertain Approved "Golgi apparatus,Plasma membrane" "Intracellular and membrane" Enzyme NA NA "Cluster 65: Brain - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 3 "Golgi apparatus" "Plasma membrane" "HPA034625: " "unprognostic (2.13e-1)" "unprognostic (3.82e-2)" "unprognostic (3.82e-2)" "unprognostic (1.78e-3)" "unprognostic (3.82e-1)" "unprognostic (6.99e-2)" "unprognostic (2.52e-1)" "unprognostic (1.71e-1)" "unprognostic (1.84e-1)" "unprognostic (2.97e-2)" "unprognostic (2.10e-1)" "unprognostic (9.16e-2)" "unprognostic (1.60e-3)" "unprognostic (8.84e-2)" "unprognostic (5.04e-2)" "unprognostic (3.68e-2)" "unprognostic (7.92e-2)" "unprognostic (1.45e-3)" "unprognostic (7.54e-2)" "unprognostic (3.60e-2)" "unprognostic (1.15e-3)" "unprognostic (2.08e-1)" "unprognostic (2.81e-1)" "unprognostic (7.29e-2)" HS6ST3 ENSG00000185352 "Heparan sulfate 6-O-sulfotransferase 3" Q8IZP7 13 96090107-96839562 "Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 6.1;brain: 16.1" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 1361.5;Bergmann glia: 1233.3;Brain excitatory neurons: 1266.9;Brain inhibitory neurons: 823.7;Choroid plexus epithelial cells: 579.8;Corticotrophs: 481.1;Lactotrophs: 890.4;Oligodendrocyte progenitor cells: 1362.7;Other brain neurons: 628.4;Pancreatic islet cells: 1236.4;Renal collecting duct intercalated cells: 758.3;Retinal ganglion cells: 1317.2;Somatotrophs: 451.6" "Cell type enhanced" "Detected in all" "mammillary body: 4377.5" "Cancer enriched" "Detected in some" 6 "Kidney Chromophobe (TCGA): 16.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 2.2;Neuroblastoma: 3.3" "Colon - Colon enteroendocrine cells, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA078257 Approved "Nucleoplasm,Nuclear membrane,Plasma membrane,Actin filaments" NA NA 44000 "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" "Nucleoplasm, Nuclear membrane" "Plasma membrane, Actin filaments" "HPA078257: " "unprognostic (2.62e-2)" "unprognostic (1.63e-2)" "unprognostic (7.19e-2)" "unprognostic (8.62e-2)" "unprognostic (3.20e-2)" "unprognostic (1.73e-1)" "unprognostic (3.85e-1)" HSBP1 ENSG00000230989 "Heat shock factor binding protein 1" O75506 16 83719311-83819737 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal efferent duct ciliated cells: 381.1;Esophageal apical cells: 1104.8;Esophageal suprabasal cells: 385.0;Late primary spermatocytes: 854.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Spleen - Fibroblasts_1, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" HPA006121 Supported "Nuclear speckles,Golgi apparatus,Plasma membrane" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 21: Non-specific - Metabolism" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 85: Squamous epithelial cells - Keratinization" 31 "Nuclear speckles, Plasma membrane" "Golgi apparatus" "HPA006121: " "unprognostic (1.45e-1)" "unprognostic (3.31e-2)" "unprognostic (8.91e-2)" "unprognostic (3.87e-2)" "unprognostic (4.02e-2)" "unprognostic (4.76e-1)" "unprognostic (9.34e-2)" "unprognostic (3.67e-2)" "potential prognostic unfavorable (6.09e-4)" "unprognostic (4.96e-2)" "potential prognostic favorable (2.57e-4)" "potential prognostic unfavorable (2.21e-4)" "unprognostic (8.30e-3)" "unprognostic (5.31e-3)" "unprognostic (1.05e-3)" "unprognostic (2.52e-1)" "unprognostic (1.56e-1)" "unprognostic (4.05e-2)" "unprognostic (4.49e-2)" "unprognostic (1.47e-2)" "unprognostic (3.91e-2)" "unprognostic (2.48e-2)" "unprognostic (2.03e-3)" "unprognostic (6.99e-2)" "unprognostic (3.47e-2)" "unprognostic (2.93e-1)" "unprognostic (5.61e-2)" "unprognostic (2.39e-2)" "unprognostic (1.79e-1)" "unprognostic (3.76e-2)" "unprognostic (2.60e-1)" HSBP1L1 "FLJ10967, MGC189743" ENSG00000226742 "Heat shock factor binding protein 1 like 1" C9JCN9 18 79964582-79970822 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Esophageal apical cells: 742.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 4 "granulocytes: 30.6;T-cells: 26.1" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA048273 Approved Approved Nucleoplasm NA NA "Cluster 41: Basophils - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 44: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 84: Apical squamous epithelium - Cornification" 8 Nucleoplasm "HPA048273: " "unprognostic (2.35e-1)" "unprognostic (3.23e-2)" "unprognostic (2.18e-3)" "unprognostic (1.74e-1)" "unprognostic (3.62e-1)" "unprognostic (1.86e-1)" "unprognostic (1.05e-2)" "unprognostic (4.27e-2)" "unprognostic (6.38e-3)" "unprognostic (1.60e-1)" "unprognostic (4.57e-2)" "unprognostic (2.61e-2)" "unprognostic (2.32e-2)" "validated prognostic unfavorable (1.64e-4)" "validated prognostic unfavorable (2.62e-4)" "unprognostic (3.03e-2)" "unprognostic (2.49e-1)" "unprognostic (1.03e-1)" "unprognostic (1.63e-1)" "unprognostic (1.33e-1)" "unprognostic (1.89e-1)" "potential prognostic unfavorable (8.22e-6)" "unprognostic (6.51e-2)" "unprognostic (5.32e-2)" "unprognostic (1.11e-3)" "unprognostic (1.78e-2)" "unprognostic (4.81e-2)" "unprognostic (9.26e-2)" "unprognostic (1.60e-1)" "unprognostic (3.48e-1)" "unprognostic (3.68e-2)" HSCB "DNAJC20, HSC20, Jac1" ENSG00000100209 "HscB mitochondrial iron-sulfur cluster cochaperone" Q8IWL3 22 28742039-28757515 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018447, HPA031518" Uncertain Supported Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 70: Non-specific - Protein processing" "Cluster 27: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 15: Non-specific - Protein processing" 89 "Nucleoplasm, Mitochondria, Cytosol" "HPA018447: , HPA031518: " "unprognostic (1.37e-1)" "unprognostic (2.05e-1)" "unprognostic (4.30e-1)" "unprognostic (9.21e-2)" "unprognostic (2.34e-2)" "unprognostic (3.33e-1)" "unprognostic (1.50e-1)" "unprognostic (7.35e-2)" "unprognostic (1.80e-1)" "unprognostic (2.17e-1)" "unprognostic (1.05e-3)" "unprognostic (1.70e-2)" "unprognostic (2.89e-1)" "unprognostic (2.49e-2)" "unprognostic (1.68e-1)" "unprognostic (1.37e-1)" "unprognostic (7.44e-2)" "unprognostic (5.63e-3)" "unprognostic (2.78e-1)" "unprognostic (1.19e-1)" "unprognostic (4.88e-2)" "unprognostic (1.22e-1)" "unprognostic (2.20e-2)" "unprognostic (7.29e-2)" "unprognostic (6.83e-3)" "unprognostic (1.98e-2)" "unprognostic (1.79e-1)" "unprognostic (2.83e-2)" "unprognostic (4.36e-1)" "unprognostic (4.83e-2)" "unprognostic (3.85e-2)" HSD11B1 "HSD11, HSD11B, SDR26C1" ENSG00000117594 "Hydroxysteroid 11-beta dehydrogenase 1" P28845 1 209686178-209734949 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "liver: 904.9" "Group enriched" "Detected in many" 4 "Endometrial luminal cells: 324.6;Hepatocytes: 893.2" "Cell type enhanced" "Detected in all" "fibroblast: 151.2" "Cancer enriched" "Detected in many" 22 "Liver Hepatocellular Carcinoma (TCGA): 301.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory CD4 T-cell: 5.7" "Lineage enriched" "Detected in single" 17 "T-cells: 5.7" "Cancer enhanced" "Detected in many" "Esophageal cancer: 20.1;thyroid cancer: 12.2" "Colon - Fibroblasts, Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047729 Enhanced NA NA 110000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 93: Hepatocytes - Bile production & excretion" 2 "HPA047729: " "unprognostic (4.56e-1)" "unprognostic (1.18e-2)" "unprognostic (8.73e-2)" "unprognostic (7.37e-2)" "unprognostic (7.37e-2)" "unprognostic (3.80e-2)" "unprognostic (6.43e-3)" "unprognostic (3.04e-2)" "unprognostic (3.67e-2)" "unprognostic (2.81e-1)" "potential prognostic unfavorable (2.18e-4)" "unprognostic (5.77e-2)" "potential prognostic unfavorable (1.03e-5)" "unprognostic (5.27e-2)" "potential prognostic favorable (9.53e-6)" "unprognostic (1.49e-2)" "unprognostic (4.64e-3)" "unprognostic (5.76e-3)" "unprognostic (1.38e-1)" "unprognostic (4.46e-1)" "unprognostic (1.79e-1)" "unprognostic (1.43e-2)" "unprognostic (1.56e-1)" "unprognostic (8.58e-2)" "unprognostic (3.83e-1)" "unprognostic (3.48e-1)" "unprognostic (1.27e-2)" "unprognostic (8.33e-3)" "unprognostic (6.62e-2)" "unprognostic (1.57e-1)" HSD11B1L "HSD1L, SCDR10, SDR26C2" ENSG00000167733 "Hydroxysteroid 11-beta dehydrogenase 1 like" Q7Z5J1 19 5680604-5688523 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "brain: 88.9" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 10.9;Epididymal clear cells: 14.3;Epididymal efferent duct ciliated cells: 24.8;Epididymal principal cells: 11.3;Fallopian tube ciliated cells: 21.0;Neuroendocrine cells: 7.8;Respiratory ciliated cells: 11.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" HPA049078 Supported Vesicles "Secreted in brain" Enzyme NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 107: Ciliated cells - Cilia assembly & function" 1 Vesicles "HPA049078: " "unprognostic (8.57e-3)" "unprognostic (8.24e-2)" "unprognostic (2.75e-2)" "unprognostic (3.33e-1)" "unprognostic (3.01e-2)" "unprognostic (1.30e-2)" "unprognostic (3.98e-1)" "unprognostic (6.05e-2)" "potential prognostic favorable (2.83e-4)" "unprognostic (5.69e-2)" "unprognostic (1.76e-1)" "unprognostic (1.70e-1)" "potential prognostic favorable (1.99e-4)" "unprognostic (1.93e-2)" "unprognostic (1.83e-1)" "potential prognostic favorable (5.89e-4)" "unprognostic (4.28e-2)" "unprognostic (2.15e-2)" "unprognostic (5.52e-3)" "unprognostic (2.27e-1)" "unprognostic (3.18e-3)" "unprognostic (5.34e-3)" "unprognostic (1.74e-1)" "unprognostic (2.36e-1)" "unprognostic (2.21e-1)" "unprognostic (4.63e-2)" "unprognostic (1.28e-1)" "unprognostic (2.54e-1)" "unprognostic (8.94e-3)" "unprognostic (1.98e-1)" "unprognostic (1.98e-2)" HSD11B2 SDR9C3 ENSG00000176387 "Hydroxysteroid 11-beta dehydrogenase 2" P80365 16 67430652-67437553 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 235.5;kidney: 324.7;salivary gland: 245.4" "Cell type enhanced" "Detected in many" "Colonocytes: 565.1;Conjunctival goblet cells: 347.6;Distal convoluted tubule cells: 277.6;Enteric transient amplifying cells: 230.8;Enterocytes: 308.9;Goblet cells: 362.7;Renal collecting duct intercalated cells: 151.5;Renal collecting duct principal cells: 212.4;Renal connecting tubule cells: 723.2;Salivary duct cells: 338.1;Salivary ionocytes: 158.9;Syncytiotrophoblasts: 262.3" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 7.2" "Cancer enriched" "Detected in all" 15 "Kidney Chromophobe (TCGA): 1271.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 16.0;prostate cancer: 15.6" "Breast - Breast glandular cells, Colon - Colon enterocytes, Kidney - Intercalated cells, Minor Salivary Gland - Minor salivary gland ductal cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB032443, HPA042186, HPA056385" Enhanced Supported Vesicles NA NA "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 37: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 3 Vesicles "CAB032443: , HPA042186: , HPA056385: " "unprognostic (5.12e-2)" "potential prognostic unfavorable (2.89e-4)" "unprognostic (2.77e-1)" "unprognostic (2.53e-1)" "unprognostic (1.75e-1)" "unprognostic (1.26e-1)" "unprognostic (6.77e-3)" "unprognostic (1.78e-3)" "unprognostic (3.07e-1)" "unprognostic (8.27e-3)" "potential prognostic favorable (4.94e-6)" "unprognostic (2.22e-3)" "unprognostic (3.52e-1)" "unprognostic (3.36e-2)" "unprognostic (1.54e-2)" "unprognostic (1.96e-1)" "unprognostic (2.21e-1)" "unprognostic (2.38e-1)" "unprognostic (2.39e-2)" "unprognostic (5.65e-3)" "unprognostic (5.62e-2)" "unprognostic (2.07e-2)" "unprognostic (1.55e-1)" "unprognostic (3.58e-1)" "unprognostic (9.85e-3)" "unprognostic (3.61e-2)" "unprognostic (1.87e-3)" "unprognostic (4.00e-2)" "unprognostic (1.71e-1)" "unprognostic (3.82e-3)" "unprognostic (8.03e-2)" HSD17B1 "EDH17B2, EDHB17, HSD17, MGC138140, SDR28C1" ENSG00000108786 "Hydroxysteroid 17-beta dehydrogenase 1" P14061 17 42552922-42555214 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "placenta: 77.5" "Cell type enriched" "Detected in some" 8 "Syncytiotrophoblasts: 107.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Testis - Sertoli cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA021032, HPA065296" Enhanced Supported Cytosol NA NA 52000 "Cluster 25: Non-specific - Unknown function" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 6: Non-specific - Immune response" "Cluster 34: Testis cancer - Unknown function" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." 1 Cytosol "HPA021032: , HPA065296: " "potential prognostic unfavorable (2.15e-4)" "unprognostic (4.58e-1)" "unprognostic (3.29e-1)" "unprognostic (3.63e-2)" "unprognostic (1.74e-1)" "unprognostic (2.81e-3)" "unprognostic (1.37e-2)" "potential prognostic favorable (6.83e-6)" "unprognostic (6.80e-2)" "unprognostic (8.25e-2)" "unprognostic (2.12e-1)" "unprognostic (1.50e-1)" "unprognostic (1.89e-1)" "unprognostic (5.99e-3)" "unprognostic (4.12e-3)" "unprognostic (1.54e-1)" "unprognostic (4.51e-1)" "unprognostic (3.40e-1)" "unprognostic (1.80e-1)" "unprognostic (1.81e-1)" "potential prognostic favorable (3.81e-4)" "unprognostic (1.50e-1)" "unprognostic (1.64e-1)" "unprognostic (5.78e-3)" "unprognostic (7.83e-2)" "unprognostic (2.21e-1)" "unprognostic (1.22e-2)" "unprognostic (5.75e-1)" "unprognostic (5.54e-2)" "unprognostic (4.10e-2)" HSD17B10 "17b-HSD10, ABAD, CAMR, ERAB, HADH2, MHBD, MRPP2, MRXS10, SDR5C1" ENSG00000072506 "Hydroxysteroid 17-beta dehydrogenase 10" Q99714 X 53431258-53434370 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Steroid metabolism, tRNA processing" Oxidoreductase "Disease variant, FDA approved drug targets, Intellectual disability, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 262.4;Esophageal basal cells: 262.8;Esophageal suprabasal cells: 430.1;Extravillous trophoblasts: 262.8;Hepatocytes: 513.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001432 Approved NA NA 420000 "Cluster 13: Non-specific - Mitochondria" "Cluster 76: Non-specific - Metabolism" "Cluster 45: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 85: Squamous epithelial cells - Keratinization" 57 "HPA001432: " "unprognostic (2.72e-1)" "unprognostic (1.08e-2)" "unprognostic (4.86e-3)" "unprognostic (7.95e-3)" "unprognostic (2.23e-1)" "unprognostic (2.02e-1)" "unprognostic (2.49e-1)" "unprognostic (9.44e-2)" "unprognostic (1.22e-1)" "unprognostic (2.17e-3)" "unprognostic (1.48e-1)" "unprognostic (4.35e-2)" "unprognostic (9.90e-2)" "unprognostic (1.22e-2)" "unprognostic (4.12e-2)" "unprognostic (1.63e-1)" "unprognostic (1.85e-2)" "unprognostic (1.41e-2)" "unprognostic (1.05e-1)" "unprognostic (1.04e-2)" "unprognostic (1.94e-1)" "unprognostic (1.36e-2)" "unprognostic (1.88e-2)" "unprognostic (1.36e-1)" "unprognostic (3.42e-1)" "unprognostic (2.04e-1)" "unprognostic (2.45e-1)" "unprognostic (1.85e-1)" "unprognostic (5.15e-2)" "unprognostic (2.90e-1)" "unprognostic (1.31e-1)" HSD17B11 "17-BETA-HSD11, 17-BETA-HSDXI, DHRS8, PAN1B, RetSDR2, SDR16C2" ENSG00000198189 "Hydroxysteroid 17-beta dehydrogenase 11" Q8NBQ5 4 87336515-87391188 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 271.8;liver: 225.9" "Cell type enhanced" "Detected in many" "Enterocytes: 148.2;Microglia: 67.9;Neutrophil progenitors: 87.5;Neutrophils: 173.7" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 83.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 772.2" "Group enriched" "Detected in all" 4 "granulocytes: 772.2;monocytes: 202.3" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021608 Enhanced Supported "Lipid droplets" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 77: Intestine - Digestion" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 79 "Lipid droplets" "HPA021608: " "unprognostic (1.26e-1)" "unprognostic (7.60e-2)" "unprognostic (1.28e-1)" "unprognostic (1.60e-1)" "unprognostic (5.50e-3)" "unprognostic (1.42e-1)" "unprognostic (3.14e-1)" "unprognostic (1.51e-1)" "unprognostic (2.19e-1)" "unprognostic (2.02e-1)" "potential prognostic favorable (5.60e-6)" "unprognostic (4.37e-3)" "unprognostic (1.66e-1)" "unprognostic (2.22e-1)" "unprognostic (3.44e-1)" "unprognostic (8.09e-3)" "unprognostic (9.16e-2)" "unprognostic (2.62e-1)" "unprognostic (1.22e-1)" "unprognostic (2.85e-3)" "unprognostic (2.69e-1)" "potential prognostic unfavorable (5.15e-4)" "unprognostic (1.80e-1)" "unprognostic (1.66e-1)" "unprognostic (2.11e-1)" "unprognostic (1.85e-2)" "unprognostic (3.64e-1)" "unprognostic (7.28e-2)" "unprognostic (5.96e-2)" "unprognostic (1.98e-2)" "unprognostic (7.97e-2)" HSD17B12 "KAR, SDR12C1" ENSG00000149084 "Hydroxysteroid 17-beta dehydrogenase 12" Q53GQ0 11 43680680-43856617 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Choroid plexus epithelial cells: 291.1;Pancreatic islet cells: 429.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016427 Approved NA NA 6900 "Cluster 30: Non-specific - DNA binding" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 24: Non-specific - Unknown function" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 39 "HPA016427: " "unprognostic (2.76e-1)" "unprognostic (1.25e-1)" "unprognostic (2.75e-1)" "unprognostic (4.67e-2)" "unprognostic (2.27e-1)" "unprognostic (6.40e-2)" "unprognostic (9.21e-2)" "potential prognostic unfavorable (5.27e-4)" "unprognostic (1.92e-3)" "unprognostic (6.07e-2)" "potential prognostic favorable (1.17e-6)" "unprognostic (3.67e-2)" "unprognostic (1.85e-2)" "potential prognostic unfavorable (3.11e-4)" "unprognostic (3.51e-2)" "unprognostic (9.71e-2)" "unprognostic (1.20e-2)" "unprognostic (2.55e-1)" "unprognostic (1.61e-1)" "unprognostic (8.91e-2)" "unprognostic (3.81e-1)" "unprognostic (2.04e-2)" "unprognostic (6.91e-3)" "unprognostic (1.39e-1)" "unprognostic (1.43e-1)" "unprognostic (9.69e-2)" "unprognostic (2.95e-2)" "unprognostic (3.02e-1)" "unprognostic (8.32e-2)" "unprognostic (2.13e-1)" "unprognostic (1.17e-2)" HSD17B13 "SCDR9, SDR16C3" ENSG00000170509 "Hydroxysteroid 17-beta dehydrogenase 13" Q7Z5P4 4 87303789-87322886 "Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 61 "liver: 536.4" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 42.1;Hepatocytes: 177.2;Prostatic club cells: 68.0;Prostatic hillock cells: 18.8;Respiratory ciliated cells: 28.0;Transitional alveolar cells: 73.2" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in some" 22 "Liver Hepatocellular Carcinoma (TCGA): 66.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 2.0" "Breast - Endothelial cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Prostate - Urothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA029125 Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 110 Vesicles "Golgi apparatus" "HPA029125: " "unprognostic (3.05e-2)" "unprognostic (2.40e-1)" "unprognostic (6.57e-2)" "unprognostic (4.53e-2)" "validated prognostic favorable (1.87e-4)" "validated prognostic favorable (2.45e-4)" "unprognostic (1.81e-3)" "potential prognostic favorable (1.88e-4)" "unprognostic (3.91e-2)" "unprognostic (1.83e-2)" "unprognostic (7.89e-2)" "unprognostic (4.14e-1)" HSD17B14 "DHRS10, retSDR3, SDR47C1" ENSG00000087076 "Hydroxysteroid 17-beta dehydrogenase 14" Q9BPX1 19 48813018-48836510 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Fucose metabolism, Lipid metabolism, Steroid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 138.6" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 167.0;Epididymal clear cells: 57.2;Epididymal efferent duct absorptive cells: 149.0;Granulosa cells: 59.2;Hofbauer cells: 294.8;Ovarian stromal cells: 70.7;Proximal tubule cells: 85.5;Retinal pigment epithelial cells: 68.2" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 107.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "B-cells: 3.7;NK-cells: 4.8;T-cells: 3.1" "Cancer enhanced" "Detected in many" "Rhabdoid: 45.6" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Stomach - Fibroblasts" "Not detected" "Not detected" HPA021467 Approved NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 5: Rhabdoid - Unknown function" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 26 "HPA021467: " "potential prognostic favorable (5.11e-4)" "unprognostic (8.46e-2)" "unprognostic (6.57e-2)" "unprognostic (5.80e-3)" "unprognostic (1.42e-3)" "unprognostic (1.39e-1)" "unprognostic (1.13e-2)" "unprognostic (3.52e-1)" "unprognostic (2.73e-1)" "unprognostic (6.58e-2)" "potential prognostic favorable (4.45e-4)" "unprognostic (1.41e-1)" "potential prognostic unfavorable (8.46e-4)" "unprognostic (9.10e-2)" "unprognostic (1.27e-1)" "unprognostic (1.66e-2)" "unprognostic (1.11e-1)" "unprognostic (1.30e-1)" "unprognostic (3.44e-2)" "unprognostic (1.61e-1)" "unprognostic (1.46e-1)" "potential prognostic favorable (1.60e-4)" "unprognostic (2.63e-1)" "unprognostic (2.27e-1)" "unprognostic (1.12e-2)" "unprognostic (1.39e-3)" "unprognostic (1.32e-1)" "unprognostic (3.38e-3)" "unprognostic (1.55e-1)" "unprognostic (4.56e-2)" "unprognostic (3.79e-1)" HSD17B2 "HSD17, SDR9C2" ENSG00000086696 "Hydroxysteroid 17-beta dehydrogenase 2" P37059 16 82035004-82098534 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 403.6;liver: 203.6;placenta: 358.5" "Cell type enhanced" "Detected in many" "Breast lactating cells: 432.3;Cholangiocytes: 262.7;Colonocytes: 215.8;Endometrial glandular cells: 242.9;Enterocytes: 491.2;Hepatocytes: 235.1;Lacrimal acinar cells: 164.9;Pancreatic duct cells: 154.1;Urothelial cells: 214.3" "Cell type enriched" "Detected in single" 4 "fibroblast: 3.3" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 106.8;Pancreatic Adenocarcinoma (TCGA): 71.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 31.8;pancreatic cancer: 35.3" "Colon - Colon enterocytes, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Urothelial cells, Stomach - Gastric mucous cells" "Group enriched" "Detected in some" 5 "midbrain: 2.2;pons and medulla: 3.4" "Not detected" "Not detected" "HPA021826, HPA050235" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 77: Intestine - Digestion" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 8 "Endoplasmic reticulum" "HPA021826: , HPA050235: " "unprognostic (2.36e-2)" "unprognostic (1.60e-1)" "unprognostic (8.49e-2)" "unprognostic (4.96e-3)" "unprognostic (1.22e-1)" "unprognostic (1.20e-2)" "unprognostic (2.81e-1)" "unprognostic (5.86e-2)" "unprognostic (2.95e-1)" "unprognostic (2.20e-1)" "unprognostic (2.77e-1)" "unprognostic (2.38e-2)" "unprognostic (7.17e-2)" "unprognostic (1.30e-1)" "unprognostic (2.63e-1)" "unprognostic (2.82e-1)" "potential prognostic unfavorable (6.21e-4)" "unprognostic (2.53e-2)" "unprognostic (1.52e-1)" "unprognostic (3.30e-1)" "unprognostic (1.38e-1)" "unprognostic (1.69e-1)" "unprognostic (4.52e-2)" "unprognostic (1.69e-1)" "unprognostic (2.28e-1)" HSD17B3 SDR12C2 ENSG00000130948 "Hydroxysteroid 17-beta dehydrogenase 3" P37058 9 96235306-96302176 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Oxidoreductase "Disease variant, Pseudohermaphroditism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 10.9;testis: 34.4" "Cell type enriched" "Detected in some" 5 "Oligodendrocytes: 79.2" "Group enriched" "Detected in many" 4 "committed oligodendrocyte precursor: 27.1;oligodendrocyte: 107.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "head and neck cancer: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA056833 Enhanced Approved Vesicles NA NA "Cluster 67: Testis - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 80: Oligodendrocytes - Myelination" 1 Vesicles "HPA056833: " "unprognostic (2.40e-2)" "unprognostic (7.76e-2)" "unprognostic (1.63e-3)" "unprognostic (1.73e-1)" "unprognostic (3.95e-2)" "unprognostic (1.02e-1)" "unprognostic (1.19e-1)" "unprognostic (1.10e-1)" "unprognostic (1.28e-2)" "unprognostic (1.68e-1)" "unprognostic (4.25e-3)" "unprognostic (1.96e-1)" HSD17B4 "DBP, MFE-2, SDR8C1" ENSG00000133835 "Hydroxysteroid 17-beta dehydrogenase 4" P51659 5 119452465-119637199 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Lyase, Oxidoreductase" "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 308.8" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 335.8;Hepatocytes: 348.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 68.5" "Group enriched" "Detected in all" 4 "dendritic cells: 20.1;granulocytes: 68.5;monocytes: 25.6" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Adrenal cortex cells, Colon - Macrophages, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021302, HPA021311, HPA021479" Enhanced Enhanced Peroxisomes NA NA 620000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 76: Non-specific - Metabolism" "Cluster 47: Endothelial cells - Vasculature" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 81: Alveolar cells - Lung function" 10 Peroxisomes "HPA021302: , HPA021311: , HPA021479: " "unprognostic (1.76e-1)" "unprognostic (9.15e-2)" "unprognostic (6.57e-2)" "potential prognostic unfavorable (6.81e-4)" "unprognostic (2.41e-3)" "unprognostic (1.43e-2)" "unprognostic (1.12e-1)" "unprognostic (1.57e-2)" "unprognostic (1.06e-1)" "unprognostic (8.54e-3)" "potential prognostic favorable (1.66e-7)" "unprognostic (4.37e-2)" "unprognostic (5.04e-2)" "unprognostic (5.83e-2)" "potential prognostic favorable (4.07e-4)" "unprognostic (9.74e-2)" "unprognostic (9.71e-2)" "unprognostic (1.03e-3)" "unprognostic (4.44e-2)" "unprognostic (2.25e-3)" "unprognostic (3.64e-1)" "unprognostic (1.33e-1)" "unprognostic (2.06e-1)" "unprognostic (3.74e-1)" "unprognostic (4.06e-3)" "potential prognostic unfavorable (5.78e-4)" "unprognostic (3.59e-1)" "unprognostic (6.83e-2)" "unprognostic (5.35e-2)" "unprognostic (1.63e-1)" "unprognostic (2.87e-1)" HSD17B6 "HSE, RODH, SDR9C6" ENSG00000025423 "Hydroxysteroid 17-beta dehydrogenase 6" O14756 12 56752161-56787790 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 26 "liver: 1686.3" "Cell type enriched" "Detected in many" 9 "Hepatocytes: 2398.0" "Group enriched" "Detected in many" 4 "astrocyte: 22.5;Bergmann glia: 55.7" "Cancer enriched" "Detected in many" 5 "Liver Hepatocellular Carcinoma (TCGA): 337.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Kidney - Fibroblasts, Liver - Hepatocytes, Liver - Hepatocytes, Skin - Smooth muscle cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA059141 Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 93: Hepatocytes - Bile production & excretion" "Nucleoplasm, Vesicles" "HPA059141: " "unprognostic (9.58e-3)" "unprognostic (5.83e-2)" "unprognostic (1.65e-2)" "unprognostic (1.14e-2)" "unprognostic (1.12e-2)" "unprognostic (1.43e-1)" "unprognostic (1.06e-1)" "unprognostic (1.36e-3)" "unprognostic (6.41e-2)" "unprognostic (1.09e-1)" "validated prognostic favorable (3.77e-4)" "validated prognostic favorable (7.84e-4)" "unprognostic (2.18e-3)" "unprognostic (1.76e-1)" "unprognostic (3.93e-2)" "unprognostic (2.11e-1)" "unprognostic (6.58e-2)" "unprognostic (2.12e-2)" "unprognostic (1.77e-1)" "unprognostic (8.58e-2)" "unprognostic (2.29e-2)" "unprognostic (1.15e-1)" "unprognostic (1.78e-2)" "unprognostic (1.50e-1)" "unprognostic (4.39e-1)" "unprognostic (6.43e-2)" "unprognostic (6.19e-2)" HSD17B7 "PRAP, SDR37C1" ENSG00000132196 "Hydroxysteroid 17-beta dehydrogenase 7" P56937 1 162790702-162812823 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 64.5" "Cell type enhanced" "Detected in many" "Breast lactating cells: 86.8;Epididymal efferent duct ciliated cells: 104.9;Epididymal principal cells: 246.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047496 Approved NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 49: Hindbrain - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 1 "HPA047496: " "unprognostic (3.24e-3)" "unprognostic (5.27e-2)" "unprognostic (6.53e-2)" "unprognostic (4.14e-2)" "unprognostic (1.18e-2)" "unprognostic (1.15e-1)" "unprognostic (1.05e-1)" "unprognostic (1.32e-2)" "potential prognostic unfavorable (3.07e-4)" "unprognostic (9.50e-2)" "potential prognostic favorable (2.24e-7)" "unprognostic (1.07e-2)" "unprognostic (2.61e-1)" "unprognostic (1.78e-1)" "unprognostic (2.26e-1)" "unprognostic (1.51e-1)" "unprognostic (1.05e-1)" "unprognostic (1.93e-1)" "unprognostic (2.80e-2)" "unprognostic (2.48e-1)" "unprognostic (1.72e-1)" "unprognostic (1.64e-1)" "unprognostic (5.99e-2)" "unprognostic (1.71e-1)" "unprognostic (2.87e-2)" "unprognostic (2.45e-1)" "unprognostic (1.67e-1)" "unprognostic (9.90e-3)" "unprognostic (2.66e-1)" "unprognostic (2.32e-1)" "unprognostic (1.31e-1)" HSD17B8 "D6S2245E, FABGL, H2-KE6, HKE6, KE6, RING2, SDR30C1" ENSG00000204228 "Hydroxysteroid 17-beta dehydrogenase 8" Q92506 6 33204655-33206831 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 55.6;Epididymal efferent duct absorptive cells: 60.1;Epididymal efferent duct ciliated cells: 53.7;Esophageal suprabasal cells: 61.8;Hepatocytes: 77.9;Plasma cells: 59.4" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 10.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042132 Enhanced NA NA 84000 "Cluster 33: Non-specific - ATP binding" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 67: Plasma cells - Plasma cell differentiation" 10 "HPA042132: " "unprognostic (1.91e-2)" "unprognostic (4.36e-3)" "unprognostic (1.53e-1)" "unprognostic (1.08e-1)" "unprognostic (7.48e-2)" "unprognostic (1.15e-1)" "unprognostic (1.12e-1)" "unprognostic (4.55e-2)" "unprognostic (4.57e-2)" "unprognostic (6.98e-2)" "potential prognostic favorable (5.38e-7)" "unprognostic (2.15e-3)" "potential prognostic favorable (2.44e-5)" "potential prognostic favorable (7.73e-5)" "unprognostic (1.59e-3)" "unprognostic (7.68e-2)" "unprognostic (2.34e-1)" "unprognostic (1.24e-1)" "unprognostic (2.23e-1)" "unprognostic (3.87e-2)" "unprognostic (4.45e-2)" "unprognostic (6.32e-2)" "unprognostic (3.04e-1)" "unprognostic (1.09e-1)" "unprognostic (2.85e-2)" "unprognostic (1.08e-2)" "unprognostic (1.39e-1)" "unprognostic (6.76e-2)" "unprognostic (2.69e-1)" "unprognostic (1.59e-1)" "unprognostic (1.04e-1)" HSD3B1 "HSD3B, HSDB3, SDR11E1" ENSG00000203857 "Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1" P14060 1 119507198-119515054 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism, Steroidogenesis" "Isomerase, Multifunctional enzyme, Oxidoreductase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "placenta: 73.1" "Cell type enhanced" "Detected in some" "Enterocytes: 44.6;Extravillous trophoblasts: 266.6;Migrating cytotrophoblasts: 142.3;Syncytiotrophoblasts: 782.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder Urothelial Carcinoma (TCGA): 4.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 15.5;Gastric cancer: 12.8;testis cancer: 24.4" "Skin - Sebaceous gland cells" "HPA043261, HPA043264, HPA044028" Supported Approved "Nucleoli,Endoplasmic reticulum,Microtubules,Cytokinetic bridge,Primary cilium,Primary cilium transition zone" Yes NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 53: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." 8 "Nucleoli, Endoplasmic reticulum, Primary cilium" "Microtubules, Cytokinetic bridge, Primary cilium transition zone" "HPA043261: , HPA043264: , HPA044028: " "unprognostic (5.46e-3)" "unprognostic (1.41e-2)" HSD3B2 SDR11E2 ENSG00000203859 "Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2" P26439 1 119414931-119423035 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroidogenesis" "Isomerase, Multifunctional enzyme, Oxidoreductase" "Congenital adrenal hyperplasia, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 53 "adrenal gland: 2103.4" "Cell type enriched" "Detected in some" 23 "Adrenal cortex cells: 2208.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Testicular Germ Cell Tumor (TCGA): 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 18 "skin cancer: 9.2" "Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells" "HPA043261, HPA043264, HPA044028" Supported Approved "Nucleoli,Endoplasmic reticulum,Microtubules,Cytokinetic bridge,Primary cilium,Primary cilium transition zone" Yes NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 53: Neurons - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 18: Adrenal cortex cells - Steroidogensis" 2 "Endoplasmic reticulum, Primary cilium" "Nucleoli, Microtubules, Cytokinetic bridge, Primary cilium transition zone" "HPA043261: , HPA043264: , HPA044028: " "unprognostic (7.33e-2)" "unprognostic (2.75e-1)" HSD3B7 "C(27)-3BETA-HSD, SDR11E3" ENSG00000099377 "Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7" Q9H2F3 16 30985207-30989147 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroidogenesis" Oxidoreductase "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 131.6" "Cell type enhanced" "Detected in many" "Cholangiocytes: 26.9;Decidual stromal cells: 44.5;Early spermatids: 49.0;Enteric stem cells: 26.0;Enteric transient amplifying cells: 28.6;Enterocytes: 38.4;Hepatocytes: 70.7;Pancreatic duct cells: 26.5;Paneth cells: 38.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 27 "basophil: 61.4;eosinophil: 27.3" "Lineage enriched" "Detected in many" 38 "granulocytes: 61.4" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015965, HPA050521, HPA060847" Approved Enhanced "Lipid droplets" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 15: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 108: Fibroblasts - ECM organization" 48 "Lipid droplets" "HPA015965: , HPA050521: , HPA060847: " "unprognostic (8.68e-2)" "unprognostic (1.03e-3)" "unprognostic (1.80e-1)" "unprognostic (6.03e-2)" "unprognostic (1.12e-2)" "unprognostic (1.18e-1)" "unprognostic (1.76e-2)" "unprognostic (2.92e-1)" "unprognostic (8.17e-3)" "unprognostic (1.22e-1)" "unprognostic (6.76e-2)" "unprognostic (1.17e-2)" "unprognostic (1.08e-1)" "unprognostic (3.45e-2)" "unprognostic (3.06e-2)" "unprognostic (3.85e-3)" "unprognostic (5.17e-2)" "unprognostic (8.39e-2)" "unprognostic (2.55e-1)" "unprognostic (1.43e-1)" "unprognostic (7.75e-2)" "unprognostic (6.15e-3)" "unprognostic (2.19e-1)" "unprognostic (9.10e-2)" "unprognostic (1.23e-1)" "unprognostic (2.80e-1)" "unprognostic (2.43e-1)" "unprognostic (2.94e-2)" "unprognostic (3.20e-2)" "unprognostic (4.69e-2)" "unprognostic (2.76e-1)" HSDL1 SDR12C3 ENSG00000103160 "Hydroxysteroid dehydrogenase like 1" Q3SXM5 16 84122141-84145192 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 59.2;Platelets: 60.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045745 Supported "Vesicles,Intermediate filaments,Mitochondria" No No "Cluster 16: Non-specific - Cell proliferation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 1: Neurons - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 79: Photoreceptor cells - Phototransduction" 15 Mitochondria "Vesicles, Intermediate filaments" "HPA045745: " "unprognostic (5.05e-2)" "unprognostic (1.86e-1)" "unprognostic (1.97e-2)" "unprognostic (3.23e-2)" "unprognostic (6.79e-2)" "unprognostic (1.61e-2)" "unprognostic (2.82e-1)" "potential prognostic favorable (2.97e-5)" "unprognostic (1.49e-1)" "unprognostic (3.95e-2)" "potential prognostic favorable (1.67e-7)" "unprognostic (1.68e-1)" "unprognostic (7.24e-2)" "unprognostic (6.97e-3)" "unprognostic (7.57e-3)" "unprognostic (1.57e-2)" "unprognostic (3.41e-1)" "unprognostic (5.02e-3)" "unprognostic (6.95e-2)" "unprognostic (2.46e-1)" "unprognostic (1.16e-2)" "unprognostic (1.28e-1)" "potential prognostic unfavorable (1.28e-4)" "unprognostic (2.39e-1)" "unprognostic (3.36e-2)" "unprognostic (7.09e-2)" "unprognostic (3.76e-1)" "unprognostic (7.34e-2)" "unprognostic (1.77e-1)" "potential prognostic unfavorable (4.20e-5)" "unprognostic (7.87e-2)" HSDL2 "C9orf99, SDR13C1" ENSG00000119471 "Hydroxysteroid dehydrogenase like 2" Q6YN16 9 112380080-112472405 "Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 169.3" "Cell type enhanced" "Detected in all" "Adipocytes: 295.8;Myonuclei: 435.0;Neutrophils: 470.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Lineage enriched" "Detected in all" 5 "granulocytes: 54.5" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042890, HPA050453" Enhanced Enhanced Mitochondria NA NA "Cluster 41: Basophils - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 24: Neutrophils - Innate immunity signal integration" 12 Mitochondria "HPA042890: , HPA050453: " "unprognostic (2.78e-2)" "unprognostic (2.48e-3)" "unprognostic (4.36e-2)" "unprognostic (2.34e-1)" "unprognostic (3.72e-3)" "unprognostic (3.16e-1)" "unprognostic (2.08e-2)" "unprognostic (2.76e-2)" "unprognostic (2.68e-1)" "unprognostic (1.94e-1)" "validated prognostic favorable (9.69e-11)" "validated prognostic favorable (7.39e-4)" "unprognostic (8.37e-2)" "unprognostic (7.05e-2)" "unprognostic (7.55e-2)" "unprognostic (1.60e-2)" "unprognostic (7.37e-2)" "unprognostic (3.53e-2)" "unprognostic (2.33e-1)" "unprognostic (4.10e-1)" "unprognostic (2.80e-1)" "unprognostic (7.17e-2)" "unprognostic (2.01e-1)" "unprognostic (1.30e-1)" "unprognostic (3.13e-2)" "unprognostic (2.67e-1)" "unprognostic (2.79e-1)" "unprognostic (8.70e-2)" "unprognostic (2.01e-1)" "unprognostic (1.79e-2)" "unprognostic (2.09e-2)" HSF1 HSTF1 ENSG00000185122 "Heat shock transcription factor 1" Q00613 8 144291591-144314720 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "DNA damage, DNA repair, Host-virus interaction, mRNA processing, mRNA transport, Stress response, Transcription, Transcription regulation, Transport" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 20.0;Bergmann glia: 22.5;Brain excitatory neurons: 19.6;Choroid plexus epithelial cells: 30.2;Distal convoluted tubule cells: 41.8;Ependymal cells: 21.0;Loop of henle epithelial cells: 36.4;Microglia: 25.7;Oligodendrocytes: 21.8;Other brain neurons: 23.1;Papillary tip epithelial cells: 44.9;Podocytes: 29.2;Proximal tubule cells: 34.1;Renal collecting duct intercalated cells: 45.6;Renal collecting duct principal cells: 45.4;Renal connecting tubule cells: 46.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004239, HPA008888" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 19: Astrocytes - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 102: Non-specific - Mixed function" 117 Nucleoplasm Cytosol "CAB004239: , HPA008888: " "unprognostic (2.77e-1)" "unprognostic (9.35e-2)" "unprognostic (1.67e-1)" "potential prognostic unfavorable (5.74e-4)" "unprognostic (6.32e-2)" "unprognostic (2.89e-3)" "unprognostic (9.69e-2)" "unprognostic (1.24e-2)" "unprognostic (1.59e-2)" "unprognostic (6.44e-3)" "unprognostic (6.97e-2)" "unprognostic (1.24e-1)" "unprognostic (1.03e-1)" "potential prognostic unfavorable (9.87e-5)" "unprognostic (1.01e-2)" "potential prognostic unfavorable (8.53e-5)" "unprognostic (3.87e-3)" "unprognostic (2.11e-2)" "unprognostic (3.24e-1)" "unprognostic (2.06e-1)" "unprognostic (3.08e-2)" "unprognostic (7.01e-3)" "potential prognostic unfavorable (6.58e-4)" "unprognostic (6.44e-2)" "unprognostic (1.33e-1)" "unprognostic (2.20e-1)" "unprognostic (8.97e-2)" "unprognostic (1.45e-1)" "unprognostic (2.10e-1)" "unprognostic (6.78e-3)" "unprognostic (1.48e-1)" HSF2 ENSG00000025156 "Heat shock transcription factor 2" Q03933 6 122399551-122433119 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Stress response, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 101.0;Late primary spermatocytes: 120.9;Myonuclei: 102.2;Thymic myoid cells: 133.2;Undifferentiated spermatogonia: 97.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016067, HPA031455" Approved Supported Nucleoplasm No No "Cluster 43: Non-specific - Transcription & Translation" "Cluster 40: Non-specific - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 27 Nucleoplasm "CAB016067: , HPA031455: " "unprognostic (1.35e-2)" "unprognostic (6.44e-3)" "potential prognostic unfavorable (3.01e-4)" "unprognostic (3.24e-1)" "unprognostic (1.39e-1)" "unprognostic (1.03e-1)" "unprognostic (5.53e-3)" "unprognostic (6.01e-3)" "unprognostic (1.25e-1)" "unprognostic (8.66e-2)" "potential prognostic favorable (5.97e-4)" "unprognostic (1.98e-1)" "unprognostic (3.15e-2)" "validated prognostic unfavorable (6.25e-7)" "validated prognostic unfavorable (1.74e-4)" "unprognostic (2.75e-2)" "unprognostic (2.94e-1)" "unprognostic (2.11e-1)" "unprognostic (8.93e-2)" "unprognostic (2.43e-1)" "unprognostic (6.37e-2)" "unprognostic (1.07e-3)" "unprognostic (7.62e-2)" "unprognostic (1.72e-1)" "unprognostic (1.51e-1)" "unprognostic (1.32e-3)" "unprognostic (1.33e-1)" "unprognostic (3.32e-2)" "unprognostic (1.54e-1)" "unprognostic (7.91e-3)" "unprognostic (1.51e-1)" HSF2BP MEILB2 ENSG00000160207 "Heat shock transcription factor 2 binding protein" O75031 21 43529186-43659488 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "testis: 22.8" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 45.8;Early primary spermatocytes: 87.5;Early spermatids: 107.0;Late primary spermatocytes: 48.3;Late spermatids: 45.3;Retinal ganglion cells: 23.2;Undifferentiated spermatogonia: 30.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 19.2" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA031724, HPA075775" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 67: Testis - Mixed function" "Cluster 27: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 232 Nucleoplasm Cytosol "HPA031724: , HPA075775: " "unprognostic (1.79e-1)" "unprognostic (1.99e-3)" "unprognostic (4.24e-2)" "unprognostic (3.95e-3)" "unprognostic (3.76e-1)" "unprognostic (1.94e-3)" "unprognostic (8.41e-3)" "unprognostic (5.51e-2)" "validated prognostic unfavorable (6.78e-4)" "validated prognostic unfavorable (8.08e-4)" "unprognostic (3.14e-1)" "unprognostic (8.21e-2)" "unprognostic (5.19e-2)" "unprognostic (4.15e-2)" "unprognostic (8.64e-3)" "unprognostic (2.31e-3)" "unprognostic (6.74e-2)" "unprognostic (1.92e-1)" "unprognostic (1.71e-1)" "unprognostic (6.85e-3)" HSF4 CTM ENSG00000102878 "Heat shock transcription factor 4" Q9ULV5 16 67164681-67169945 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Stress response, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 31.9;Astrocytes: 42.4;Hofbauer cells: 54.3;Leydig cells: 60.4;Melanocytes: 38.1;Myonuclei: 44.9;Peritubular myoid cells: 34.1;Retinal ganglion cells: 42.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048584 Supported "Nuclear speckles" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 20: Myeloma - Immune response" "Cluster 94: Gonadal somatic cells - Mixed function" 13 "Nuclear speckles" "HPA048584: " "unprognostic (8.87e-2)" "unprognostic (1.05e-1)" "unprognostic (1.23e-1)" "unprognostic (2.84e-2)" "unprognostic (8.89e-3)" "unprognostic (1.66e-2)" "unprognostic (6.55e-2)" "unprognostic (8.94e-2)" "unprognostic (2.50e-1)" "unprognostic (1.76e-1)" "unprognostic (1.39e-2)" "unprognostic (1.76e-2)" "unprognostic (1.83e-2)" "unprognostic (8.98e-2)" "unprognostic (1.03e-1)" "unprognostic (3.16e-3)" "unprognostic (1.90e-1)" "unprognostic (8.70e-2)" "unprognostic (1.34e-1)" "unprognostic (3.02e-1)" "unprognostic (8.92e-3)" "unprognostic (3.56e-3)" "unprognostic (8.20e-2)" "unprognostic (1.20e-1)" "unprognostic (1.11e-1)" "unprognostic (1.13e-2)" "unprognostic (4.00e-2)" "unprognostic (1.58e-2)" "unprognostic (1.15e-1)" "unprognostic (3.98e-3)" "unprognostic (1.75e-1)" HSF5 FLJ40311 ENSG00000176160 "Heat shock transcription factor 5" Q4G112 17 58420167-58488408 "Predicted intracellular proteins, Transcription factors" "Differentiation, Meiosis, Spermatogenesis, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 41 "testis: 45.6" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 50.3;Early spermatids: 35.5;Hematopoietic stem cells: 25.2;Late primary spermatocytes: 135.2;Late spermatids: 17.0;Megakaryocyte-Erythroid progenitors: 16.7;pDCs: 26.5;Retinal ganglion cells: 27.0" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 5 "B-cells: 1.3;T-cells: 1.1" "Not detected" "Not detected" "Spleen - B-cells (Spleen), Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA016440, HPA063613" Enhanced Approved Nucleoplasm NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 57: Testis - Spermatogenesis" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 2 Nucleoplasm "HPA016440: , HPA063613: " HSFX1 LW-1 ENSG00000171116 "Heat shock transcription factor family, X-linked 1" Q9UBD0 X 149774068-149776867 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 6.0" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA051700, HPA063040" Approved Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 21: Testis - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 27: Breast cancer - Unknown function" 13 Nucleoplasm "Plasma membrane, Cytosol" "HPA051700: , HPA063040: " "unprognostic (1.91e-1)" "unprognostic (2.68e-2)" HSFX2 ENSG00000268738 "Heat shock transcription factor family, X-linked 2" Q9UBD0 X 149592512-149595314 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 5.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA051700, HPA063040" Supported Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 21: Testis - Mixed function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 27: Breast cancer - Unknown function" 9 Nucleoplasm "Plasma membrane, Cytosol" "HPA051700: , HPA063040: " "unprognostic (2.68e-2)" "unprognostic (3.03e-1)" HSFX3 ENSG00000283697 "Heat shock transcription factor family, X-linked member 3" A0A1B0GWH4 X 149548210-149549924 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 10 "testis: 13.1" "Group enriched" "Detected in some" 8 "Early spermatids: 91.4;Late primary spermatocytes: 112.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Prostate Adenocarcinoma (TCGA): 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 47: Leukemia - Hemostasis" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" "unprognostic (1.09e-1)" HSFX4 ENSG00000283463 "Heat shock transcription factor family, X-linked member 4" A0A1B0GTS1 X 149929573-149931287 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 6 "testis: 15.1" "Group enriched" "Detected in some" 7 "Early spermatids: 121.5;Late primary spermatocytes: 133.5" "Group enriched" "Detected in some" 13 "Prostate Adenocarcinoma (TCGA): 1.9;Uterine Corpus Endometrial Carcinoma (TCGA): 1.8" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 15: Non-specific - Transcription" "Cluster 47: Leukemia - Hemostasis" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" "unprognostic (2.14e-1)" "unprognostic (6.32e-2)" HSFY1 "HSF2L, HSFY" ENSG00000172468 "Heat shock transcription factor Y-linked 1" Q96LI6 Y 18546691-18588963 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 18 "testis: 13.8" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "Bladder Urothelial Carcinoma (TCGA): 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA074968 Supported Nucleoplasm,Cytosol NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 24 "Nucleoplasm, Cytosol" "HPA074968: " "unprognostic (1.08e-1)" HSFY2 FLJ25453 ENSG00000169953 "Heat shock transcription factor Y-linked 2" Q96LI6 Y 18731440-18773735 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 31 "testis: 19.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA074968 Supported Nucleoplasm,Cytosol NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 1: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" 19 "Nucleoplasm, Cytosol" "HPA074968: " HSH2D "ALX, FLJ14886, HSH2" ENSG00000196684 "Hematopoietic SH2 domain containing" Q96JZ2 19 16134028-16158575 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 44.4;lymphoid tissue: 36.2" "Cell type enhanced" "Detected in many" "B-cells: 99.7;Foveolar cells: 69.5;Hematopoietic stem cells: 133.0;Innate lymphoid cells: 94.5;Megakaryocyte-Erythroid progenitors: 111.7;Neutrophils: 71.5;NK-cells: 205.9;Plasma cells: 227.2;Thymocytes: 206.7" "Cell type enriched" "Detected in some" 37 "leukocyte: 68.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 233.0" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Leukemia: 50.4;lymphoma: 32.0;Myeloma: 29.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Heart muscle - T-cells, Minor Salivary Gland - Plasma cells, Pituitary gland - Gonadotropes, Prostate - Prostate glandular cells, Spleen - B-cells (Spleen), Stomach - Gastric mucous cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA036616 Approved "Plasma membrane,Focal adhesion sites,Cytosol" NA NA "Cluster 32: Basophils - Transcription" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 11: White matter - Signal transduction" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 8 "Plasma membrane" "Focal adhesion sites, Cytosol" "HPA036616: " "unprognostic (1.48e-2)" "unprognostic (2.27e-1)" "unprognostic (5.12e-1)" "unprognostic (3.73e-2)" "unprognostic (1.10e-1)" "unprognostic (1.78e-1)" "unprognostic (1.20e-2)" "unprognostic (1.16e-1)" "validated prognostic unfavorable (7.29e-7)" "validated prognostic unfavorable (5.23e-4)" "unprognostic (1.35e-1)" "unprognostic (6.68e-2)" "unprognostic (1.77e-1)" "unprognostic (2.23e-1)" "unprognostic (2.61e-1)" "unprognostic (1.79e-1)" "unprognostic (6.65e-2)" "unprognostic (6.00e-2)" "unprognostic (2.27e-1)" "unprognostic (3.33e-3)" "unprognostic (3.11e-2)" "unprognostic (4.91e-2)" "unprognostic (1.17e-1)" "unprognostic (9.40e-3)" "unprognostic (1.52e-1)" "unprognostic (7.15e-2)" "unprognostic (3.84e-2)" "unprognostic (6.00e-2)" "unprognostic (1.20e-1)" HSP90AA1 "FLJ31884, Hsp89, Hsp90, HSP90N, HSPC1, HSPCA" ENSG00000080824 "Heat shock protein 90 alpha family class A member 1" P07900 14 102080742-102139699 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Stress response" "Chaperone, Hydrolase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epididymal efferent duct absorptive cells: 6812.2;Pancreatic duct cells: 6948.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002058, HPA047290" Approved Supported Nucleoplasm,Cytosol NA NA 110000000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 75: Non-specific - Chaperones and protein folding" 500 Cytosol Nucleoplasm "CAB002058: , HPA047290: " "unprognostic (2.47e-2)" "unprognostic (1.41e-3)" "unprognostic (1.08e-1)" "unprognostic (1.64e-1)" "unprognostic (1.77e-1)" "unprognostic (2.93e-1)" "unprognostic (3.28e-1)" "potential prognostic unfavorable (6.86e-5)" "potential prognostic unfavorable (8.12e-4)" "unprognostic (1.39e-1)" "potential prognostic favorable (4.80e-6)" "unprognostic (2.05e-2)" "unprognostic (9.88e-2)" "potential prognostic unfavorable (1.15e-5)" "unprognostic (1.95e-2)" "unprognostic (1.85e-3)" "unprognostic (1.44e-3)" "unprognostic (1.92e-1)" "unprognostic (2.22e-1)" "unprognostic (3.92e-2)" "unprognostic (1.48e-3)" "unprognostic (2.46e-2)" "potential prognostic unfavorable (5.35e-5)" "unprognostic (2.81e-2)" "unprognostic (2.56e-1)" "unprognostic (7.65e-2)" "unprognostic (1.22e-1)" "unprognostic (2.61e-1)" "unprognostic (4.62e-1)" "unprognostic (1.29e-1)" "unprognostic (2.42e-2)" HSP90AB1 "HSPC2, HSPCB" ENSG00000096384 "Heat shock protein 90 alpha family class B member 1" P08238 6 44246166-44253888 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Stress response" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreatic duct cells: 2924.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005230, HPA072606, HPA074351" Enhanced Supported "Plasma membrane,Cytosol" "Intracellular and membrane" Other NA Yes 96000000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 75: Non-specific - Chaperones and protein folding" 439 "Plasma membrane" Cytosol "CAB005230: , HPA072606: , HPA074351: " "unprognostic (1.00e-2)" "unprognostic (5.04e-3)" "unprognostic (4.49e-2)" "unprognostic (3.54e-2)" "unprognostic (3.94e-2)" "unprognostic (1.18e-2)" "unprognostic (1.39e-1)" "unprognostic (3.45e-2)" "potential prognostic unfavorable (2.78e-5)" "unprognostic (4.53e-1)" "potential prognostic favorable (3.74e-6)" "unprognostic (9.79e-3)" "potential prognostic unfavorable (4.28e-4)" "validated prognostic unfavorable (3.93e-4)" "validated prognostic unfavorable (2.93e-4)" "unprognostic (3.90e-2)" "unprognostic (4.65e-3)" "unprognostic (8.69e-2)" "unprognostic (1.12e-1)" "unprognostic (3.98e-2)" "unprognostic (1.90e-1)" "unprognostic (7.34e-2)" "unprognostic (5.62e-2)" "unprognostic (2.37e-2)" "unprognostic (1.66e-2)" "unprognostic (2.86e-1)" "unprognostic (7.07e-2)" "unprognostic (1.53e-1)" "unprognostic (1.64e-1)" "unprognostic (7.39e-2)" "unprognostic (2.73e-1)" HSP90B1 "GP96, GRP94, TRA1" ENSG00000166598 "Heat shock protein 90 beta family member 1" P14625 12 103930107-103953931 "Cancer-related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Chaperone, Hydrolase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 1322.6" "Cell type enhanced" "Detected in all" "Epididymal basal cells: 1705.7;Epididymal principal cells: 4063.4;Plasma cells: 3857.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003901, CAB005224, HPA008424, CAB078151" Enhanced Enhanced "Endoplasmic reticulum" "Intracellular and membrane" Enzyme NA NA 210000000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 22: Epididymis - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 44: Plasma cells - Antibody production & secretion" 115 "Endoplasmic reticulum" "CAB005224: , CAB078151: , HPA003901: , HPA008424: " "potential prognostic unfavorable (7.88e-4)" "unprognostic (3.22e-2)" "unprognostic (5.68e-2)" "unprognostic (3.15e-3)" "unprognostic (3.86e-2)" "unprognostic (2.76e-2)" "unprognostic (1.46e-2)" "potential prognostic unfavorable (3.91e-4)" "potential prognostic unfavorable (8.28e-4)" "unprognostic (8.52e-2)" "potential prognostic favorable (1.98e-4)" "unprognostic (2.81e-3)" "unprognostic (1.31e-2)" "unprognostic (3.87e-3)" "unprognostic (3.49e-2)" "unprognostic (2.97e-2)" "unprognostic (4.66e-1)" "unprognostic (7.21e-2)" "unprognostic (6.31e-2)" "unprognostic (3.31e-1)" "unprognostic (4.25e-2)" "unprognostic (2.54e-2)" "potential prognostic unfavorable (5.04e-4)" "unprognostic (1.90e-1)" "unprognostic (2.41e-1)" "unprognostic (6.93e-2)" "unprognostic (1.37e-1)" "unprognostic (1.52e-1)" "unprognostic (2.31e-1)" "unprognostic (2.76e-2)" "unprognostic (3.78e-1)" HSPA12A "FLJ13874, KIAA0417" ENSG00000165868 "Heat shock protein family A (Hsp70) member 12A" O43301 10 116671192-116850251 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.0" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 240.1;Brain inhibitory neurons: 225.4;Choroid plexus epithelial cells: 370.1;Ependymal cells: 222.1;Gonadotrophs: 202.4;Podocytes: 322.6;Retinal ganglion cells: 312.9;Schwann cells: 317.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 14 "memory B-cell: 1.4;naive B-cell: 1.8;T-reg: 1.0" "Group enriched" "Detected in many" 14 "B-cells: 1.8;T-cells: 1.0" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Testis - Peritubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011273, HPA073244" Approved Approved "Golgi apparatus,Cytosol" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 61: Schwann cells & Melanocytes - Mixed function" 32 "Golgi apparatus, Cytosol" "HPA011273: , HPA073244: " "unprognostic (2.16e-2)" "unprognostic (3.64e-2)" "unprognostic (2.20e-1)" "unprognostic (7.86e-3)" "unprognostic (4.84e-1)" "unprognostic (1.39e-1)" "unprognostic (2.00e-1)" "unprognostic (2.40e-1)" "unprognostic (1.03e-1)" "unprognostic (6.93e-2)" "potential prognostic favorable (5.26e-6)" "unprognostic (5.16e-3)" "unprognostic (7.44e-2)" "unprognostic (4.57e-3)" "unprognostic (8.47e-2)" "unprognostic (7.85e-2)" "unprognostic (1.17e-1)" "unprognostic (1.15e-1)" "unprognostic (4.65e-2)" "unprognostic (8.13e-2)" "unprognostic (1.70e-2)" "unprognostic (9.92e-2)" "unprognostic (2.25e-2)" "unprognostic (1.46e-2)" "unprognostic (1.64e-2)" "unprognostic (1.54e-1)" "unprognostic (5.08e-2)" "unprognostic (1.66e-1)" "unprognostic (2.03e-1)" "unprognostic (8.28e-3)" HSPA12B "C20orf60, dJ1009E24.2" ENSG00000132622 "Heat shock protein family A (Hsp70) member 12B" Q96MM6 20 3732685-3753111 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Early spermatids: 8.5;Epicardial cells: 9.1;Fibro-adipogenic progenitors: 15.3;Fibroblasts: 10.5;Late primary spermatocytes: 10.8;Late spermatids: 31.5;Leydig cells: 8.0;Lymphatic endothelial cells: 37.2;Ovarian stromal cells: 7.5;Peritubular myoid cells: 14.3;Vascular endothelial cells: 49.4" "Cell type enriched" "Detected in some" 6 "endothelial cell: 104.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013659, HPA015639" Uncertain Approved Nucleoplasm NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 7: Liver cancer - Metabolism" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 17 Nucleoplasm "HPA013659: , HPA015639: " "unprognostic (5.00e-2)" "unprognostic (5.87e-2)" "unprognostic (6.32e-2)" "unprognostic (5.55e-2)" "unprognostic (2.91e-2)" "unprognostic (1.10e-1)" "unprognostic (2.28e-2)" "unprognostic (2.90e-1)" "unprognostic (2.55e-1)" "unprognostic (2.17e-1)" "validated prognostic favorable (3.54e-6)" "validated prognostic favorable (8.00e-5)" "unprognostic (1.94e-3)" "unprognostic (7.40e-2)" "unprognostic (2.55e-3)" "unprognostic (3.28e-1)" "unprognostic (8.79e-2)" "unprognostic (5.40e-2)" "unprognostic (1.75e-3)" "unprognostic (2.74e-2)" "unprognostic (1.49e-2)" "unprognostic (6.58e-2)" "unprognostic (5.04e-1)" "unprognostic (3.78e-2)" "unprognostic (1.97e-2)" "unprognostic (4.21e-2)" "unprognostic (4.85e-1)" "unprognostic (2.45e-3)" "unprognostic (2.11e-1)" "unprognostic (5.49e-2)" "unprognostic (9.80e-3)" HSPA13 STCH ENSG00000155304 "Heat shock protein family A (Hsp70) member 13" P48723 21 14371115-14383484 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Corticotrophs: 79.3;Plasma cells: 126.3;Syncytiotrophoblasts: 95.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014797 Approved "Intracellular and membrane" "No annotated function" NA NA 2300000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 63: Non-specific - Protein processing" "Cluster 78: Plasma cells - Antibody production & ER-stress response" 52 "HPA014797: " "unprognostic (2.49e-2)" "unprognostic (1.88e-2)" "unprognostic (9.74e-3)" "unprognostic (2.77e-2)" "unprognostic (1.22e-1)" "unprognostic (1.25e-1)" "unprognostic (8.39e-2)" "unprognostic (2.57e-2)" "unprognostic (2.02e-1)" "unprognostic (2.48e-2)" "potential prognostic favorable (3.07e-7)" "unprognostic (7.08e-2)" "unprognostic (5.17e-2)" "unprognostic (1.81e-3)" "unprognostic (3.12e-3)" "unprognostic (6.57e-3)" "unprognostic (1.15e-1)" "unprognostic (4.78e-2)" "unprognostic (1.51e-1)" "unprognostic (1.11e-1)" "unprognostic (2.03e-3)" "unprognostic (7.83e-2)" "unprognostic (3.24e-3)" "unprognostic (9.95e-2)" "unprognostic (8.83e-2)" "unprognostic (1.32e-1)" "unprognostic (1.49e-1)" "unprognostic (1.45e-1)" "unprognostic (1.02e-1)" "unprognostic (5.99e-2)" "unprognostic (1.33e-1)" HSPA14 "HSP70-4, HSP70L1" ENSG00000187522 "Heat shock protein family A (Hsp70) member 14" Q0VDF9 10 14838306-14871741 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 178.9;Late primary spermatocytes: 133.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046180 Approved NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 3: Early primary spermatocytes - Early meiosis" 24 "HPA046180: " "unprognostic (1.19e-1)" "unprognostic (2.15e-3)" "unprognostic (2.98e-2)" "potential prognostic favorable (6.08e-4)" "unprognostic (2.23e-1)" "potential prognostic favorable (1.68e-4)" "unprognostic (1.87e-2)" "potential prognostic favorable (3.35e-7)" "unprognostic (1.11e-2)" "potential prognostic unfavorable (1.45e-5)" "unprognostic (7.44e-2)" "unprognostic (4.15e-3)" "unprognostic (2.83e-2)" "validated prognostic unfavorable (2.05e-6)" "validated prognostic unfavorable (7.19e-4)" "unprognostic (8.76e-2)" "unprognostic (3.28e-1)" "unprognostic (2.46e-3)" "unprognostic (5.22e-2)" "potential prognostic favorable (3.85e-5)" "unprognostic (1.93e-1)" "unprognostic (2.33e-1)" "unprognostic (6.45e-2)" "unprognostic (3.82e-3)" "unprognostic (4.69e-3)" "unprognostic (2.16e-1)" "unprognostic (3.92e-1)" "unprognostic (4.56e-2)" "unprognostic (1.26e-1)" "unprognostic (4.77e-3)" "unprognostic (5.93e-2)" HSPA1A "HSP70-1, HSPA1" ENSG00000204389 "Heat shock protein family A (Hsp70) member 1A" P0DMV8 6 31815543-31817946 "Disease related genes, Predicted intracellular proteins" "Host-virus interaction, Stress response" "Chaperone, Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 395.9;Bergmann glia: 176.6;Ependymal cells: 349.6;Microglia: 1396.3;Oligodendrocytes: 190.1" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 1466.5;endothelial cell: 1181.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "granulocytes: 6.9;monocytes: 3.6;T-cells: 3.1" "Cancer enhanced" "Detected in many" "cervical cancer: 45.8" "CAB017451, CAB032815, HPA052504" Supported Approved "Vesicles,Perinuclear theca,Calyx,Flagellar centriole,Annulus" "Intracellular and membrane" Receptor NA Yes 100000000 "Cluster 4: Neutrophils - Degranulation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 66: Non-specific - Mitochondria" "Cluster 104: Brain endothelial cells - Blood brain barrier" 326 "Vesicles, Flagellar centriole, Annulus" "Perinuclear theca, Calyx" "CAB017451: , CAB032815: , HPA052504: " "unprognostic (3.59e-2)" "unprognostic (6.42e-2)" "unprognostic (4.07e-1)" "unprognostic (6.46e-3)" "unprognostic (1.13e-1)" "unprognostic (2.86e-1)" "unprognostic (1.80e-2)" "unprognostic (2.63e-1)" "unprognostic (1.54e-1)" "unprognostic (1.42e-1)" "unprognostic (2.08e-3)" "unprognostic (4.04e-2)" "unprognostic (2.36e-1)" "unprognostic (1.04e-3)" "unprognostic (1.06e-1)" "unprognostic (4.48e-2)" "unprognostic (4.08e-1)" "unprognostic (2.23e-1)" "unprognostic (9.49e-2)" "potential prognostic unfavorable (3.20e-5)" "unprognostic (7.76e-3)" "unprognostic (1.70e-1)" "potential prognostic unfavorable (5.83e-4)" "unprognostic (2.07e-2)" "unprognostic (4.86e-2)" "unprognostic (1.70e-1)" "unprognostic (1.10e-1)" "unprognostic (2.12e-1)" "unprognostic (3.79e-2)" "unprognostic (2.18e-1)" "unprognostic (1.40e-1)" HSPA1B HSP70-2 ENSG00000204388 "Heat shock protein family A (Hsp70) member 1B" P0DMV9 6 31827738-31830254 "Predicted intracellular proteins" "Host-virus interaction, Stress response" "Chaperone, Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 5 "Astrocytes: 179.1;Ependymal cells: 337.4;Microglia: 551.8" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 558.7;endothelial cell: 432.4;ependymal cell: 350.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 7.1" "CAB008640, HPA052504" Approved Supported "Vesicles,Cytosol,Perinuclear theca,Calyx,Flagellar centriole,Annulus" NA Yes "Cluster 64: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 104: Brain endothelial cells - Blood brain barrier" 76 "Vesicles, Cytosol, Flagellar centriole, Annulus" "Perinuclear theca, Calyx" "CAB008640: , HPA052504: " "unprognostic (1.35e-1)" "unprognostic (3.08e-1)" "unprognostic (2.44e-1)" "unprognostic (1.29e-1)" "unprognostic (7.95e-2)" "unprognostic (1.77e-1)" "unprognostic (2.58e-1)" "unprognostic (2.86e-1)" "unprognostic (1.59e-1)" "unprognostic (1.14e-1)" "potential prognostic favorable (8.31e-4)" "unprognostic (1.44e-1)" "unprognostic (1.35e-2)" "unprognostic (3.63e-2)" "unprognostic (3.43e-1)" "unprognostic (5.85e-1)" "unprognostic (2.79e-1)" "unprognostic (4.04e-3)" "unprognostic (1.52e-1)" "unprognostic (2.55e-1)" "potential prognostic unfavorable (2.28e-4)" "unprognostic (6.51e-3)" "unprognostic (3.04e-2)" "unprognostic (9.72e-2)" "unprognostic (1.55e-1)" "unprognostic (1.35e-1)" "unprognostic (5.19e-3)" "unprognostic (1.84e-1)" "unprognostic (2.23e-1)" "unprognostic (3.12e-1)" HSPA1L "HSP70-HOM, hum70t" ENSG00000204390 "Heat shock protein family A (Hsp70) member 1 like" P34931 6 31809619-31815283 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 16 "testis: 54.8" "Cell type enhanced" "Detected in some" "Astrocytes: 1.5;Ependymal cells: 2.7;Late spermatids: 1.4;Microglia: 1.7;Oligodendrocytes: 1.2;Podocytes: 1.5" "Cell type enhanced" "Detected in many" "ependymal cell: 4.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA043285, HPA052504" Enhanced Approved "Vesicles,Perinuclear theca,Calyx,Flagellar centriole,Annulus" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 25: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 102: Non-specific - Mixed function" 51 "Vesicles, Flagellar centriole, Annulus" "Perinuclear theca, Calyx" "HPA043285: , HPA052504: " "unprognostic (1.26e-1)" "unprognostic (4.24e-2)" "unprognostic (8.61e-3)" "unprognostic (1.67e-1)" "unprognostic (5.31e-2)" HSPA2 ENSG00000126803 "Heat shock protein family A (Hsp70) member 2" P54652 14 64535905-64546173 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis, Stress response" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 344.7;skeletal muscle: 177.8" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 453.3;Extravillous trophoblasts: 732.7;Hepatic stellate cells: 193.6;Late primary spermatocytes: 716.2;Migrating cytotrophoblasts: 163.3;Oligodendrocytes: 152.1" "Cell type enhanced" "Detected in many" "ependymal cell: 67.8;oligodendrocyte: 184.0;pericyte: 75.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.2" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Prostate - Smooth muscle cells, Spleen - Fibroblasts_2, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "HPA000798, HPA052504" Enhanced Supported Approved "Vesicles,Perinuclear theca,Calyx,Flagellar centriole,Annulus" NA NA 89000000 "Cluster 25: Non-specific - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 133 "Vesicles, Flagellar centriole, Annulus" "Perinuclear theca, Calyx" "HPA000798: , HPA052504: " "unprognostic (1.34e-1)" "unprognostic (5.10e-3)" "unprognostic (1.76e-3)" "unprognostic (3.16e-1)" "unprognostic (1.05e-1)" "unprognostic (1.17e-1)" "unprognostic (4.85e-2)" "potential prognostic unfavorable (1.36e-4)" "unprognostic (2.62e-2)" "unprognostic (4.34e-1)" "unprognostic (1.06e-1)" "unprognostic (1.55e-1)" "unprognostic (1.99e-1)" "unprognostic (4.97e-2)" "unprognostic (1.13e-1)" "unprognostic (3.40e-3)" "unprognostic (6.77e-2)" "unprognostic (3.14e-2)" "unprognostic (5.10e-2)" "unprognostic (5.82e-2)" "unprognostic (9.54e-3)" "unprognostic (3.47e-1)" "unprognostic (1.74e-1)" "unprognostic (3.08e-1)" "unprognostic (8.88e-2)" "unprognostic (7.24e-2)" "unprognostic (1.59e-1)" "unprognostic (6.20e-2)" "unprognostic (1.17e-1)" "unprognostic (4.60e-1)" "unprognostic (9.43e-2)" HSPA4 "HS24/P52, HSPH2" ENSG00000170606 "Heat shock protein family A (Hsp70) member 4" P34932 5 133052013-133106449 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Stress response" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 303.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010023, CAB025529" Uncertain Approved Nucleoplasm,Cytosol NA NA 13000000 "Cluster 29: Non-specific - Unknown function" "Cluster 42: Retina - Visual perception" "Cluster 21: Non-specific - Metabolism" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 75: Non-specific - Chaperones and protein folding" 209 "Nucleoplasm, Cytosol" "CAB025529: , HPA010023: " "unprognostic (4.36e-2)" "unprognostic (6.69e-2)" "unprognostic (1.90e-1)" "unprognostic (2.17e-3)" "unprognostic (1.16e-2)" "unprognostic (1.61e-2)" "unprognostic (1.40e-1)" "unprognostic (7.83e-3)" "unprognostic (1.57e-2)" "unprognostic (1.65e-3)" "potential prognostic favorable (2.28e-5)" "unprognostic (2.31e-1)" "unprognostic (9.91e-2)" "unprognostic (3.24e-3)" "unprognostic (2.65e-2)" "potential prognostic unfavorable (8.93e-4)" "unprognostic (5.95e-2)" "unprognostic (9.26e-2)" "unprognostic (1.39e-1)" "unprognostic (5.60e-2)" "unprognostic (3.84e-2)" "unprognostic (2.12e-3)" "unprognostic (3.67e-3)" "unprognostic (2.54e-2)" "unprognostic (7.18e-2)" "unprognostic (7.45e-2)" "unprognostic (5.16e-2)" "unprognostic (1.56e-1)" "unprognostic (1.44e-1)" "unprognostic (9.75e-3)" "unprognostic (4.14e-1)" HSPA4L "APG-1, HSPH3, Osp94" ENSG00000164070 "Heat shock protein family A (Hsp70) member 4 like" O95757 4 127781821-127840733 "Plasma proteins, Predicted intracellular proteins" "Stress response" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "testis: 101.7" "Cell type enhanced" "Detected in many" "Early spermatids: 539.2;Late primary spermatocytes: 409.6;Late spermatids: 1609.1;Pancreatic duct cells: 240.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 1.1" "Lineage enriched" "Detected in single" 8 "granulocytes: 1.1" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal cortex cells, Breast - Breast myoepithelial cells, Minor Salivary Gland - Minor salivary gland basal cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034450, HPA039149, HPA061446" Enhanced Approved "Centrosome,Cytosol,Perinuclear theca,Calyx" NA NA 640000 "Cluster 22: Eosinophils - Transcription" "Cluster 47: Testis - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 41 Cytosol "Centrosome, Perinuclear theca, Calyx" "CAB034450: , HPA039149: , HPA061446: " "unprognostic (3.21e-1)" "unprognostic (2.85e-1)" "unprognostic (7.22e-2)" "unprognostic (5.13e-2)" "unprognostic (1.03e-2)" "unprognostic (3.79e-1)" "unprognostic (3.54e-1)" "unprognostic (5.98e-3)" "unprognostic (5.91e-2)" "potential prognostic unfavorable (1.08e-4)" "validated prognostic favorable (1.32e-10)" "validated prognostic favorable (8.64e-4)" "unprognostic (7.97e-2)" "unprognostic (1.84e-2)" "unprognostic (3.44e-1)" "unprognostic (1.00e-1)" "unprognostic (4.63e-3)" "unprognostic (7.85e-2)" "unprognostic (8.46e-2)" "unprognostic (1.06e-2)" "unprognostic (2.34e-1)" "unprognostic (1.34e-1)" "unprognostic (1.15e-2)" "unprognostic (1.94e-1)" "unprognostic (9.04e-2)" "unprognostic (2.42e-1)" "unprognostic (5.01e-1)" "unprognostic (1.33e-1)" "unprognostic (1.85e-1)" "unprognostic (1.55e-1)" "unprognostic (4.71e-2)" HSPA5 "BiP, GRP78" ENSG00000044574 "Heat shock protein family A (Hsp70) member 5" P11021 9 125234853-125241382 "Disease related genes, Enzymes, Essential proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Host-virus interaction" "Chaperone, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epididymal basal cells: 2675.2;Epididymal principal cells: 2135.9;Extravillous trophoblasts: 1248.3;Plasma cells: 1402.5;Syncytiotrophoblasts: 1846.5" "Cell type enhanced" "Detected in all" "endothelial cell: 281.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005221, HPA038845, HPA038846" Enhanced Uncertain "Cytosol,Mid piece,Principal piece,End piece,Annulus" "Intracellular and membrane" Enzyme NA NA 540000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 22: Epididymis - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 8: Non-specific - Secretory pathway" 449 "Cytosol, Annulus" "Mid piece, Principal piece, End piece" "CAB005221: , HPA038845: , HPA038846: " "potential prognostic unfavorable (3.50e-4)" "unprognostic (9.55e-2)" "unprognostic (2.39e-1)" "unprognostic (2.26e-2)" "unprognostic (1.02e-1)" "unprognostic (3.81e-3)" "unprognostic (1.12e-2)" "potential prognostic unfavorable (4.18e-4)" "unprognostic (7.65e-3)" "unprognostic (5.89e-2)" "unprognostic (1.44e-3)" "unprognostic (2.56e-2)" "potential prognostic unfavorable (1.44e-4)" "unprognostic (4.57e-3)" "unprognostic (3.52e-3)" "unprognostic (6.09e-2)" "unprognostic (5.84e-3)" "unprognostic (3.32e-2)" "unprognostic (3.57e-2)" "unprognostic (2.09e-1)" "unprognostic (2.53e-2)" "unprognostic (5.46e-2)" "unprognostic (1.68e-2)" "unprognostic (1.72e-1)" "unprognostic (6.16e-2)" "unprognostic (4.41e-2)" "unprognostic (6.59e-2)" "unprognostic (7.42e-2)" "unprognostic (8.46e-2)" "unprognostic (5.90e-2)" "unprognostic (2.50e-2)" HSPA6 HSP70B' ENSG00000173110 "Heat shock protein family A (Hsp70) member 6" P17066 1 161524540-161526894 "Plasma proteins, Predicted intracellular proteins" "Stress response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 88.5" "Cell type enriched" "Detected in some" 5 "Microglia: 14.7" "Group enriched" "Detected in some" 5 "central nervous system macrophage: 20.5;endothelial cell: 8.6;leukocyte: 23.2" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 125.6" "Immune cell enriched" "Detected in many" 7 "neutrophil: 319.0" "Lineage enriched" "Detected in many" 7 "granulocytes: 319.0" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "CAB017452, HPA028549, HPA052504" Approved Approved "Vesicles,Perinuclear theca,Calyx,Flagellar centriole,Annulus" NA NA 49000000 "Cluster 28: Neutrophils - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 11: Neuronal - Sensory perception" "Cluster 102: Non-specific - Mixed function" 53 "Vesicles, Flagellar centriole, Annulus" "Perinuclear theca, Calyx" "CAB017452: , HPA028549: , HPA052504: " "unprognostic (1.28e-1)" "unprognostic (2.77e-2)" "unprognostic (2.65e-2)" "unprognostic (5.32e-2)" "unprognostic (2.21e-2)" "unprognostic (2.89e-1)" "unprognostic (1.49e-2)" "unprognostic (7.16e-2)" "unprognostic (6.34e-3)" "unprognostic (1.88e-1)" "unprognostic (1.51e-3)" "unprognostic (3.00e-2)" "unprognostic (3.06e-1)" "unprognostic (1.98e-3)" "unprognostic (2.92e-1)" "unprognostic (7.79e-2)" "potential prognostic unfavorable (2.78e-4)" "unprognostic (8.23e-2)" "unprognostic (3.39e-1)" "unprognostic (1.14e-2)" "unprognostic (5.86e-2)" "unprognostic (1.81e-1)" "potential prognostic unfavorable (9.66e-6)" "unprognostic (7.83e-2)" "unprognostic (2.56e-1)" "unprognostic (1.37e-3)" "unprognostic (2.24e-1)" "unprognostic (6.75e-2)" "unprognostic (1.23e-1)" "potential prognostic unfavorable (7.58e-4)" "unprognostic (5.18e-2)" HSPA8 "HSC70, HSC71, HSP73, HSPA10" ENSG00000109971 "Heat shock protein family A (Hsp70) member 8" P11142 11 123057489-123063230 "Cancer-related genes, Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Autophagy, Host-virus interaction, mRNA processing, mRNA splicing, Stress response, Transcription, Transcription regulation" "Chaperone, Hydrolase, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Breast lactating cells: 1372.1;Epididymal principal cells: 1371.6;Syncytiotrophoblasts: 1639.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002056, HPA052504" Uncertain Supported "Vesicles,Perinuclear theca,Calyx,Flagellar centriole,Annulus" NA Yes 210000000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 20: Non-specific - Transcription regulation" 697 "Vesicles, Flagellar centriole, Annulus" "Perinuclear theca, Calyx" "CAB002056: , HPA052504: " "unprognostic (4.00e-3)" "unprognostic (8.77e-3)" "unprognostic (7.60e-2)" "unprognostic (3.63e-2)" "unprognostic (1.23e-2)" "unprognostic (2.15e-1)" "unprognostic (1.16e-1)" "unprognostic (1.34e-1)" "unprognostic (4.27e-2)" "unprognostic (4.83e-3)" "potential prognostic favorable (6.02e-7)" "unprognostic (3.11e-2)" "unprognostic (2.44e-1)" "potential prognostic unfavorable (5.07e-5)" "unprognostic (1.08e-1)" "unprognostic (2.54e-2)" "unprognostic (8.25e-3)" "unprognostic (9.36e-2)" "unprognostic (4.62e-2)" "unprognostic (6.21e-3)" "unprognostic (2.64e-2)" "unprognostic (2.72e-1)" "unprognostic (8.81e-2)" "unprognostic (2.52e-1)" "unprognostic (2.24e-2)" "unprognostic (3.57e-1)" "unprognostic (3.73e-1)" "unprognostic (1.22e-1)" "unprognostic (6.57e-2)" "unprognostic (2.35e-1)" "unprognostic (8.42e-2)" HSPA9 "GRP75, HSPA9B, mot-2, mthsp75, PBP74" ENSG00000113013 "Heat shock protein family A (Hsp70) member 9" P38646 5 138553756-138575675 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Chaperone, Hydrolase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 620.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000898, CAB005219" Supported Supported Mitochondria NA NA 4100000 "Cluster 33: Non-specific - ATP binding" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 103: Non-specific - Basic cellular processes" 118 Mitochondria "CAB005219: , HPA000898: " "unprognostic (2.11e-1)" "unprognostic (7.61e-3)" "unprognostic (1.67e-1)" "unprognostic (1.54e-2)" "potential prognostic favorable (8.25e-4)" "unprognostic (2.04e-1)" "unprognostic (2.91e-1)" "unprognostic (2.09e-3)" "unprognostic (8.99e-2)" "potential prognostic unfavorable (7.23e-6)" "potential prognostic favorable (5.36e-9)" "unprognostic (2.40e-2)" "unprognostic (5.61e-2)" "unprognostic (3.93e-1)" "unprognostic (1.36e-1)" "unprognostic (9.22e-3)" "unprognostic (1.44e-1)" "unprognostic (1.42e-1)" "unprognostic (1.58e-1)" "unprognostic (1.62e-1)" "unprognostic (3.04e-2)" "unprognostic (7.03e-3)" "unprognostic (9.13e-2)" "unprognostic (1.13e-1)" "unprognostic (4.13e-2)" "unprognostic (1.65e-1)" "unprognostic (1.45e-1)" "unprognostic (2.29e-1)" "unprognostic (1.42e-1)" "unprognostic (2.02e-2)" "unprognostic (7.92e-2)" HSPB1 "CMT2F, Hs.76067, Hsp25, HSP27, HSP28" ENSG00000106211 "Heat shock protein family B (small) member 1" P04792 7 76302673-76304295 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Stress response" Chaperone "Cancer-related genes, Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 6918.5" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 6655.6;Epididymal efferent duct absorptive cells: 4667.1;Esophageal apical cells: 36565.4;Esophageal basal cells: 10114.9;Esophageal suprabasal cells: 24428.9" "Cell type enhanced" "Detected in all" "endothelial cell: 342.9;vascular associated smooth muscle cell: 632.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Smooth muscle cells, Prostate - Smooth muscle cells, Skin - Keratinocyte (other), Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000497, CAB004439, CAB047330, CAB047331, CAB047332" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA 25000000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 39: Astrocytes - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 85: Squamous epithelial cells - Keratinization" 281 "Plasma membrane, Cytosol" "CAB004439: , CAB047330: , CAB047331: , CAB047332: , HPA000497: " "unprognostic (3.29e-2)" "unprognostic (1.15e-1)" "unprognostic (2.75e-2)" "unprognostic (3.05e-2)" "unprognostic (2.39e-2)" "unprognostic (1.28e-2)" "unprognostic (3.57e-3)" "potential prognostic unfavorable (8.42e-4)" "unprognostic (1.37e-2)" "unprognostic (1.43e-2)" "unprognostic (7.75e-2)" "potential prognostic unfavorable (8.89e-4)" "unprognostic (1.24e-2)" "unprognostic (6.90e-3)" "unprognostic (1.07e-3)" "unprognostic (2.91e-1)" "unprognostic (2.65e-2)" "unprognostic (1.60e-1)" "unprognostic (1.04e-1)" "unprognostic (1.24e-1)" "unprognostic (3.00e-1)" "unprognostic (3.59e-2)" "unprognostic (3.08e-1)" "unprognostic (3.18e-1)" "potential prognostic unfavorable (8.01e-4)" "unprognostic (9.54e-2)" "unprognostic (1.22e-1)" "unprognostic (3.89e-2)" "unprognostic (2.14e-1)" "unprognostic (1.22e-1)" "unprognostic (1.62e-2)" HSPB11 "C1orf41, FAP232, HSPCO34, IFT25, PP25" ENSG00000081870 "Heat shock protein family B (small) member 11" Q9Y547 1 53916574-53945699 "Predicted intracellular proteins" "Differentiation, Protein transport, Spermatogenesis, Stress response, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial ciliated cells: 284.2;Fallopian tube ciliated cells: 319.0;Respiratory ciliated cells: 367.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030140 Uncertain Approved "Mid piece,Principal piece,End piece" NA NA 110000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 22: Epididymis - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 107: Ciliated cells - Cilia assembly & function" 62 "Mid piece, Principal piece, End piece" "HPA030140: " "unprognostic (1.06e-1)" "unprognostic (9.26e-2)" "unprognostic (1.08e-1)" "potential prognostic favorable (5.76e-4)" "unprognostic (6.19e-2)" "unprognostic (1.68e-1)" "potential prognostic unfavorable (2.79e-4)" "unprognostic (1.19e-1)" "unprognostic (2.45e-1)" "potential prognostic unfavorable (1.05e-5)" "unprognostic (6.30e-2)" "unprognostic (4.50e-2)" "unprognostic (6.70e-2)" "potential prognostic unfavorable (1.15e-7)" "unprognostic (2.42e-2)" "unprognostic (1.36e-2)" "unprognostic (7.65e-3)" "unprognostic (1.06e-1)" "unprognostic (4.36e-1)" "unprognostic (9.11e-3)" "unprognostic (5.81e-2)" "unprognostic (1.18e-1)" "unprognostic (2.00e-2)" "unprognostic (2.11e-1)" "unprognostic (1.40e-1)" "unprognostic (2.25e-1)" "unprognostic (5.74e-3)" "unprognostic (8.42e-2)" "unprognostic (2.16e-1)" "potential prognostic unfavorable (6.26e-4)" "unprognostic (1.69e-2)" HSPB2 "Hs.78846, MKBP" ENSG00000170276 "Heat shock protein family B (small) member 2" Q16082 11 111912734-111914093 "Predicted intracellular proteins" "Stress response" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 219.0;skeletal muscle: 235.6;tongue: 295.9" "Cell type enhanced" "Detected in some" "Astrocytes: 5.4;Bergmann glia: 6.1;Brain excitatory neurons: 4.7;Brain inhibitory neurons: 1.6;Ependymal cells: 1.7;Hepatic stellate cells: 6.5;Oligodendrocytes: 4.3;Other brain neurons: 1.5;Vascular smooth muscle cells: 1.3" "Cell type enhanced" "Detected in many" "fibroblast: 21.8;vascular associated smooth muscle cell: 22.8" "Cancer enhanced" "Detected in all" "Kidney Renal Papillary Cell Carcinoma (TCGA): 68.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 11.6;Rhabdoid: 11.4;Sarcoma: 11.7" "Liver - Hepatic stellate cells, Skin - Fibroblasts_2, Spleen - Fibroblasts_2, Stomach - Fibroblasts" "Low region specificity" "Detected in all" HPA079414 Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 41: Striated muscle - Muscle contraction" "Cluster 25: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 98: Neurons - Neurotransmission & signaling" 35 "Golgi apparatus" Nucleoplasm "HPA079414: " "unprognostic (1.90e-1)" "unprognostic (4.10e-2)" "unprognostic (3.07e-1)" "unprognostic (1.55e-1)" "unprognostic (5.60e-3)" "unprognostic (8.22e-2)" "unprognostic (3.49e-2)" "unprognostic (1.74e-2)" "unprognostic (2.76e-2)" "unprognostic (2.91e-2)" "unprognostic (1.70e-2)" "unprognostic (2.43e-1)" "potential prognostic favorable (2.99e-5)" "unprognostic (1.35e-1)" "unprognostic (6.03e-2)" "unprognostic (3.12e-1)" "unprognostic (2.41e-1)" "unprognostic (1.22e-2)" "unprognostic (1.35e-1)" "unprognostic (4.75e-3)" "unprognostic (2.53e-2)" "unprognostic (2.30e-2)" "unprognostic (1.40e-2)" "unprognostic (7.57e-2)" "unprognostic (7.52e-2)" "unprognostic (3.16e-2)" "unprognostic (1.98e-1)" "unprognostic (7.97e-3)" "unprognostic (1.03e-1)" "unprognostic (6.03e-3)" "unprognostic (5.59e-2)" HSPB3 HSPL27 ENSG00000169271 "Heat shock protein family B (small) member 3" Q12988 5 54455699-54456377 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Stress response" "Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 19 "heart muscle: 463.9;skeletal muscle: 232.7;tongue: 204.1" "Cell type enriched" "Detected in some" 6 "Thymic myoid cells: 195.8" "Cell type enhanced" "Detected in many" "lower rhombic lip: 11.6;MGE interneuron: 9.0;upper-layer intratelencephalic: 8.0" "Group enriched" "Detected in many" 5 "Head and Neck Squamous Cell Carcinoma (TCGA): 15.9;Lung Squamous Cell Carcinoma (TCGA): 5.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "Bile duct cancer: 34.2" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Cardiomyocytes, Pituitary gland - Corticotropes, Prostate - Smooth muscle cells, Spleen - Smooth muscle cells, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebral cortex: 1.1" HPA062124 Supported "Nuclear speckles" NA NA "Cluster 41: Striated muscle - Muscle contraction" "Cluster 53: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 46: Skeletal myocytes - Muscle structure & formation" "Nuclear speckles" "HPA062124: " "potential prognostic unfavorable (1.97e-4)" "unprognostic (1.57e-1)" "unprognostic (6.42e-3)" "unprognostic (3.77e-1)" "unprognostic (2.71e-1)" "unprognostic (4.47e-3)" "unprognostic (6.31e-2)" "unprognostic (1.68e-1)" "unprognostic (2.28e-1)" HSPB6 "FLJ32389, Hsp20, PPP1R91" ENSG00000004776 "Heat shock protein family B (small) member 6" O14558 19 35754566-35758079 "Predicted intracellular proteins" "Stress response" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 2832.4;tongue: 1642.4" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 734.3;Endometrial stromal cells: 111.6;Fibroblasts: 153.0;Hepatic stellate cells: 264.6;Late spermatids: 87.1;Leydig cells: 254.2;Ovarian stromal cells: 106.8;Pericytes: 129.7;Peritubular myoid cells: 195.1;Smooth muscle cells: 264.8;Thymic myoid cells: 311.4;Vascular smooth muscle cells: 240.7" "Cell type enhanced" "Detected in some" "ependymal cell: 6.6;vascular associated smooth muscle cell: 22.9" "Cancer enhanced" "Detected in all" "Stomach Adenocarcinoma (TCGA): 248.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 63.8" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Colon - Smooth muscle cells, Heart muscle - Cardiomyocytes, Kidney - Fibroblasts, Lung - Smooth muscle cells, Pituitary gland - Fibroblasts, Skeletal muscle - Skeletal myocytes, Spleen - Smooth muscle cells, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001974, HPA044153, HPA054811" Enhanced Supported "Nuclear speckles,Mitochondria,Cytosol" "Intracellular and membrane" Other NA NA 380000 "Cluster 25: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 4 "Mitochondria, Cytosol" "Nuclear speckles" "CAB001974: , HPA044153: , HPA054811: " "unprognostic (3.29e-3)" "unprognostic (1.29e-1)" "unprognostic (1.92e-2)" "unprognostic (1.21e-1)" "unprognostic (3.06e-3)" "unprognostic (3.69e-2)" "unprognostic (3.83e-3)" "unprognostic (7.13e-3)" "unprognostic (2.81e-2)" "unprognostic (3.20e-2)" "unprognostic (1.23e-1)" "unprognostic (1.49e-2)" "unprognostic (1.10e-3)" "unprognostic (6.86e-2)" "unprognostic (2.81e-3)" "unprognostic (5.23e-3)" "unprognostic (6.69e-2)" "unprognostic (6.08e-2)" "unprognostic (2.14e-1)" "unprognostic (1.76e-1)" "unprognostic (1.99e-1)" "unprognostic (1.18e-1)" "unprognostic (2.11e-1)" "unprognostic (1.35e-2)" "unprognostic (4.61e-2)" "unprognostic (2.53e-2)" "unprognostic (2.68e-1)" "unprognostic (1.05e-2)" "unprognostic (1.52e-1)" "unprognostic (6.68e-2)" "unprognostic (1.71e-2)" HSPB7 cvHSP ENSG00000173641 "Heat shock protein family B (small) member 7" Q9UBY9 1 16014028-16019594 "Predicted intracellular proteins" "Stress response" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 3567.7;skeletal muscle: 2065.4;tongue: 1148.4" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 493.7;Late spermatids: 129.5;Myonuclei: 231.9;Smooth muscle cells: 81.1;Thymic myoid cells: 581.9;Vascular smooth muscle cells: 76.0" "Group enriched" "Detected in some" 4 "pericyte: 9.2;vascular associated smooth muscle cell: 26.3" "Cancer enhanced" "Detected in many" "Stomach Adenocarcinoma (TCGA): 33.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 15.8;Brain cancer: 8.8;thyroid cancer: 8.3" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Spleen - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA027639 Approved Approved Nucleoplasm NA NA 50000 "Cluster 41: Striated muscle - Muscle contraction" "Cluster 43: Hindbrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 18 Nucleoplasm "HPA027639: " "unprognostic (5.46e-3)" "unprognostic (9.28e-2)" "unprognostic (6.12e-2)" "unprognostic (6.26e-3)" "unprognostic (1.04e-2)" "unprognostic (2.51e-2)" "unprognostic (7.76e-2)" "potential prognostic unfavorable (4.18e-4)" "unprognostic (2.88e-3)" "unprognostic (1.60e-2)" "unprognostic (4.53e-2)" "unprognostic (4.46e-2)" "unprognostic (1.59e-3)" "unprognostic (2.23e-2)" "unprognostic (3.57e-1)" "potential prognostic unfavorable (5.53e-5)" "unprognostic (1.70e-2)" "unprognostic (7.23e-3)" "unprognostic (7.98e-2)" "unprognostic (6.55e-2)" "unprognostic (6.47e-2)" "unprognostic (1.34e-1)" "unprognostic (9.18e-3)" "unprognostic (1.44e-2)" "unprognostic (6.34e-3)" "unprognostic (1.84e-2)" "unprognostic (9.86e-2)" "unprognostic (1.25e-1)" "unprognostic (1.56e-1)" HSPB8 "CMT2L, E2IG1, H11, HSP22" ENSG00000152137 "Heat shock protein family B (small) member 8" Q9UJY1 12 119171555-119224855 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Stress response" Chaperone "Charcot-Marie-Tooth disease, Disease variant, Myofibrillar myopathy, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 952.9" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 308.1;Endometrial luminal cells: 264.2;Ependymal cells: 273.0;Epididymal basal cells: 338.5;Esophageal apical cells: 725.6;Smooth muscle cells: 319.0;Syncytiotrophoblasts: 2162.3;Thymic myoid cells: 511.2" "Group enriched" "Detected in many" 5 "astrocyte: 334.5;ependymal cell: 288.9;vascular associated smooth muscle cell: 84.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Smooth muscle cells, Kidney - Proximal tubular cells, Prostate - Smooth muscle cells, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015876 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 87 Cytosol Nucleoplasm "HPA015876: " "unprognostic (3.25e-1)" "unprognostic (1.53e-2)" "unprognostic (1.30e-1)" "unprognostic (2.74e-1)" "unprognostic (1.16e-2)" "unprognostic (3.88e-3)" "unprognostic (1.61e-1)" "unprognostic (3.89e-2)" "unprognostic (6.74e-2)" "unprognostic (1.02e-1)" "unprognostic (1.13e-3)" "unprognostic (3.68e-1)" "unprognostic (1.15e-1)" "potential prognostic unfavorable (2.98e-4)" "unprognostic (9.07e-2)" "unprognostic (6.08e-3)" "unprognostic (3.47e-2)" "unprognostic (1.37e-3)" "unprognostic (2.62e-1)" "unprognostic (2.91e-2)" "unprognostic (3.44e-2)" "unprognostic (1.44e-2)" "unprognostic (2.90e-2)" "unprognostic (6.50e-2)" "unprognostic (1.34e-2)" "unprognostic (4.31e-2)" "unprognostic (2.06e-2)" "unprognostic (5.07e-3)" "unprognostic (9.47e-2)" "unprognostic (5.04e-2)" "unprognostic (4.07e-1)" HSPB9 CT51 ENSG00000260325 "Heat shock protein family B (small) member 9" Q9BQS6 17 42122804-42123352 "Predicted intracellular proteins" "Stress response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "testis: 65.5" "Cell type enriched" "Detected in some" 4 "Late spermatids: 1561.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Liver Hepatocellular Carcinoma (TCGA): 5.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA053091 Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 23: Testis - Spermatogenesis" "Cluster 6: Non-specific - Immune response" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 1 Nucleoplasm "Vesicles, Cytosol" "HPA053091: " "unprognostic (1.60e-2)" "unprognostic (1.57e-3)" "unprognostic (4.39e-2)" "unprognostic (4.26e-2)" "unprognostic (1.33e-1)" "unprognostic (6.07e-3)" "unprognostic (2.37e-1)" "unprognostic (2.68e-1)" HSPBAP1 "FLJ22623, PASS1" ENSG00000169087 "HSPB1 associated protein 1" Q96EW2 3 122739999-122793831 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglia: 153.5;Myonuclei: 151.2;Neutrophils: 343.5;Syncytiotrophoblasts: 108.4;Thymic myoid cells: 110.1" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 197.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044930 Approved Approved Mitochondria NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 61: Non-specific - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 24: Neutrophils - Innate immunity signal integration" 8 Mitochondria "HPA044930: " "unprognostic (1.49e-2)" "unprognostic (2.93e-1)" "unprognostic (1.37e-1)" "unprognostic (2.92e-2)" "unprognostic (2.73e-2)" "unprognostic (2.38e-3)" "unprognostic (4.90e-2)" "unprognostic (2.24e-2)" "unprognostic (4.86e-2)" "unprognostic (7.00e-2)" "unprognostic (3.24e-3)" "unprognostic (1.54e-1)" "unprognostic (1.92e-2)" "potential prognostic unfavorable (1.64e-6)" "unprognostic (1.44e-3)" "unprognostic (6.42e-2)" "unprognostic (3.14e-1)" "unprognostic (2.65e-1)" "unprognostic (2.08e-1)" "unprognostic (3.88e-3)" "unprognostic (1.77e-1)" "unprognostic (7.52e-2)" "unprognostic (4.54e-3)" "unprognostic (2.21e-2)" "unprognostic (5.14e-3)" "unprognostic (6.02e-3)" "unprognostic (1.17e-1)" "unprognostic (9.44e-2)" "unprognostic (4.01e-2)" "unprognostic (1.22e-1)" "unprognostic (1.64e-1)" HSPBP1 FES1 ENSG00000133265 "HSPA (Hsp70) binding protein 1" Q9NZL4 19 55262223-55280381 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 118.3" "Cell type enhanced" "Detected in many" "Epididymal efferent duct ciliated cells: 136.8;Esophageal basal cells: 90.7;Fallopian tube ciliated cells: 109.5;Respiratory ciliated cells: 144.7" "Cell type enhanced" "Detected in all" "ependymal cell: 69.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005865, HPA070398, HPA071444" Supported Approved Vesicles,Centrosome,Cytosol NA NA 11000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 107: Ciliated cells - Cilia assembly & function" 62 Cytosol "Vesicles, Centrosome" "CAB005865: , HPA070398: , HPA071444: " "unprognostic (2.27e-2)" "unprognostic (1.89e-1)" "unprognostic (1.65e-1)" "unprognostic (2.96e-2)" "unprognostic (2.40e-1)" "unprognostic (1.85e-1)" "unprognostic (1.19e-1)" "unprognostic (1.69e-1)" "unprognostic (1.61e-1)" "unprognostic (1.19e-1)" "unprognostic (2.16e-1)" "unprognostic (4.93e-1)" "unprognostic (2.97e-3)" "validated prognostic unfavorable (3.53e-4)" "validated prognostic unfavorable (1.10e-4)" "unprognostic (1.77e-3)" "unprognostic (2.36e-2)" "unprognostic (1.49e-1)" "unprognostic (1.40e-1)" "unprognostic (8.08e-2)" "unprognostic (5.81e-2)" "unprognostic (3.90e-3)" "unprognostic (1.14e-1)" "unprognostic (1.67e-2)" "unprognostic (1.88e-1)" "unprognostic (1.79e-1)" "unprognostic (9.44e-2)" "unprognostic (1.41e-1)" "unprognostic (1.11e-1)" "unprognostic (9.05e-2)" "unprognostic (1.87e-1)" HSPD1 "GroEL, HSP60, SPG13" ENSG00000144381 "Heat shock protein family D (Hsp60) member 1" P10809 2 197486584-197516737 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction" "Chaperone, Isomerase" "Cancer-related genes, Disease variant, Hereditary spastic paraplegia, Leukodystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 696.8" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 1003.7;Pancreatic duct cells: 1374.2;Syncytiotrophoblasts: 1066.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001523, CAB002775, HPA050025, CAB072816" Supported Enhanced Mitochondria NA NA 66000000 "Cluster 33: Non-specific - ATP binding" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 75: Non-specific - Chaperones and protein folding" 253 Mitochondria "CAB002775: , CAB072816: , HPA001523: , HPA050025: " "unprognostic (1.27e-3)" "unprognostic (1.46e-2)" "unprognostic (3.22e-1)" "unprognostic (1.55e-1)" "unprognostic (1.79e-2)" "unprognostic (2.33e-1)" "unprognostic (3.23e-1)" "unprognostic (6.66e-2)" "unprognostic (1.04e-3)" "unprognostic (1.57e-2)" "potential prognostic favorable (6.64e-5)" "unprognostic (1.19e-1)" "unprognostic (2.66e-3)" "validated prognostic unfavorable (6.92e-6)" "validated prognostic unfavorable (1.24e-6)" "potential prognostic unfavorable (4.42e-5)" "unprognostic (1.58e-3)" "unprognostic (4.67e-2)" "unprognostic (2.17e-2)" "unprognostic (2.66e-2)" "unprognostic (2.18e-2)" "unprognostic (3.91e-3)" "potential prognostic unfavorable (1.63e-4)" "unprognostic (3.82e-3)" "unprognostic (7.27e-3)" "unprognostic (2.38e-1)" "unprognostic (1.34e-1)" "unprognostic (5.37e-2)" "unprognostic (5.88e-2)" "unprognostic (2.56e-2)" "unprognostic (5.12e-2)" HSPE1 "CPN10, EPF, GroES, HSP10" ENSG00000115541 "Heat shock protein family E (Hsp10) member 1" P61604 2 197500140-197503449 "Cancer-related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Stress response" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 1080.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 875.6;Epididymal efferent duct absorptive cells: 1324.7;Epididymal efferent duct ciliated cells: 850.7;Hepatocytes: 994.7;Syncytiotrophoblasts: 894.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "CAB017366, HPA038755, HPA048272" Supported NA Yes 2000000 "Cluster 30: Non-specific - DNA binding" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 55: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 75: Non-specific - Chaperones and protein folding" 21 "CAB017366: , HPA038755: , HPA048272: " "unprognostic (2.95e-1)" "unprognostic (2.19e-3)" "unprognostic (1.33e-1)" "unprognostic (4.85e-1)" "unprognostic (2.25e-1)" "unprognostic (2.80e-2)" "unprognostic (1.27e-2)" "unprognostic (7.33e-3)" "unprognostic (1.86e-3)" "unprognostic (1.04e-1)" "unprognostic (2.16e-1)" "unprognostic (1.56e-2)" "potential prognostic unfavorable (4.41e-4)" "unprognostic (6.44e-3)" "potential prognostic unfavorable (4.98e-6)" "unprognostic (2.55e-3)" "unprognostic (2.24e-2)" "unprognostic (1.49e-1)" "unprognostic (7.86e-2)" "potential prognostic favorable (5.73e-4)" "unprognostic (4.37e-2)" "unprognostic (9.87e-3)" "unprognostic (3.04e-2)" "potential prognostic unfavorable (7.34e-4)" "unprognostic (1.76e-1)" "unprognostic (2.09e-1)" "unprognostic (4.67e-2)" "unprognostic (2.54e-2)" "unprognostic (9.42e-2)" "unprognostic (2.99e-1)" "unprognostic (3.65e-1)" HSPE1-MOB4 ENSG00000270757 "HSPE1-MOB4 readthrough" 2 197500413-197550726 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 18.0" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 22.3;Tuft cells: 23.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA038755, HPA044125, HPA048272" Approved NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 75: Non-specific - Chaperones and protein folding" 2 "HPA038755: , HPA044125: , HPA048272: " "unprognostic (4.92e-2)" "unprognostic (4.93e-2)" "unprognostic (4.09e-2)" "unprognostic (1.28e-1)" "unprognostic (4.97e-3)" "unprognostic (2.90e-2)" "unprognostic (1.70e-1)" "unprognostic (3.32e-2)" "potential prognostic favorable (6.32e-5)" "unprognostic (1.60e-1)" "unprognostic (7.78e-2)" "unprognostic (1.30e-2)" "unprognostic (1.12e-1)" "unprognostic (1.44e-2)" "unprognostic (4.79e-2)" "unprognostic (9.07e-2)" "unprognostic (3.85e-2)" "unprognostic (2.86e-2)" "unprognostic (3.28e-2)" "unprognostic (2.28e-2)" "unprognostic (9.19e-2)" "unprognostic (4.00e-2)" "unprognostic (8.03e-3)" "unprognostic (2.26e-1)" "unprognostic (2.91e-1)" "unprognostic (4.45e-1)" HSPG2 "perlecan, PRCAN, SJS1" ENSG00000142798 "Heparan sulfate proteoglycan 2" P98160 1 21822244-21937310 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 245.5" "Cell type enhanced" "Detected in many" "Adipocytes: 230.7;Alveolar cells type 1: 306.7;Extravillous trophoblasts: 254.2;Fibro-adipogenic progenitors: 530.0;Hepatic stellate cells: 213.0;Lacrimal acinar cells: 250.9;Schwann cells: 349.2;Smooth muscle cells: 261.7;Vascular endothelial cells: 585.7" "Cell type enhanced" "Detected in many" "endothelial cell: 97.4;fibroblast: 104.3;vascular associated smooth muscle cell: 106.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Colon - Smooth muscle cells, Liver - Vascular endothelial cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB009820, HPA018892, CAB020718, HPA072690" Approved "Secreted to extracellular matrix" "Developmental protein" NA NA 470000000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 30 "CAB009820: , CAB020718: , HPA018892: , HPA072690: " "unprognostic (2.61e-1)" "unprognostic (3.08e-1)" "unprognostic (7.79e-2)" "unprognostic (1.43e-2)" "unprognostic (1.13e-1)" "unprognostic (1.43e-1)" "unprognostic (3.13e-2)" "unprognostic (6.24e-2)" "unprognostic (1.02e-1)" "unprognostic (8.65e-2)" "potential prognostic favorable (8.54e-8)" "unprognostic (5.27e-3)" "potential prognostic unfavorable (7.06e-5)" "unprognostic (4.07e-1)" "unprognostic (5.43e-3)" "unprognostic (7.32e-2)" "unprognostic (5.60e-2)" "unprognostic (5.97e-2)" "unprognostic (3.13e-1)" "unprognostic (7.98e-3)" "unprognostic (2.39e-1)" "unprognostic (1.06e-1)" "unprognostic (2.59e-1)" "unprognostic (1.14e-1)" "unprognostic (1.78e-2)" "unprognostic (3.56e-3)" "unprognostic (2.53e-1)" "unprognostic (1.70e-2)" "unprognostic (5.10e-2)" "unprognostic (1.31e-2)" "unprognostic (1.10e-1)" HSPH1 "HSP105A, HSP105B, KIAA0201, NY-CO-25" ENSG00000120694 "Heat shock protein family H (Hsp110) member 1" Q92598 13 31134973-31162388 "Cancer-related genes, Predicted intracellular proteins" "Stress response" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epididymal efferent duct absorptive cells: 694.2;monocytes: 942.6;Pancreatic duct cells: 2047.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002060, HPA028675, HPA031569" Uncertain Enhanced Nucleoplasm,Cytosol No Yes 1000000 "Cluster 33: Non-specific - ATP binding" "Cluster 78: Brain - Neuronal signaling" "Cluster 31: Non-specific - Transcription" "Cluster 19: Non-specific - Unknown function" "Cluster 75: Non-specific - Chaperones and protein folding" 78 Cytosol Nucleoplasm "CAB002060: , HPA028675: , HPA031569: " "unprognostic (4.50e-2)" "potential prognostic unfavorable (7.11e-4)" "unprognostic (1.25e-1)" "unprognostic (8.26e-2)" "unprognostic (1.54e-1)" "unprognostic (3.33e-1)" "unprognostic (5.81e-2)" "unprognostic (1.55e-1)" "potential prognostic unfavorable (3.06e-4)" "unprognostic (5.47e-2)" "unprognostic (2.00e-1)" "unprognostic (6.16e-2)" "unprognostic (1.19e-2)" "potential prognostic unfavorable (1.28e-4)" "unprognostic (1.81e-2)" "unprognostic (1.20e-2)" "unprognostic (1.06e-2)" "unprognostic (1.27e-1)" "unprognostic (1.80e-1)" "unprognostic (1.15e-1)" "unprognostic (5.65e-2)" "unprognostic (2.55e-1)" "potential prognostic unfavorable (1.13e-6)" "unprognostic (2.68e-1)" "unprognostic (2.59e-1)" "unprognostic (6.21e-2)" "unprognostic (2.14e-1)" "unprognostic (3.80e-1)" "unprognostic (4.56e-1)" "unprognostic (2.32e-1)" "unprognostic (3.44e-2)" HTATIP2 "CC3, FLJ26963, SDR44U1, TIP30" ENSG00000109854 "HIV-1 Tat interactive protein 2" Q9BUP3 11 20363685-20383782 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction, Translation regulation" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 257.5;Esophageal suprabasal cells: 178.7;Platelets: 295.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Macrophages, Pituitary gland - Somatotropes, Stomach - Gastric mucous cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006417, HPA024321" Approved Supported Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 77: Intestine - Digestion" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 6 Cytosol "HPA006417: , HPA024321: " "unprognostic (3.54e-3)" "potential prognostic unfavorable (6.40e-4)" "unprognostic (2.82e-2)" "unprognostic (1.07e-1)" "unprognostic (2.47e-2)" "unprognostic (1.48e-1)" "unprognostic (2.81e-3)" "unprognostic (2.24e-2)" "unprognostic (1.26e-2)" "unprognostic (2.83e-3)" "unprognostic (1.87e-2)" "unprognostic (1.28e-3)" "unprognostic (1.77e-1)" "unprognostic (1.21e-3)" "unprognostic (4.39e-2)" "potential prognostic unfavorable (2.50e-4)" "unprognostic (2.59e-1)" "unprognostic (2.24e-1)" "unprognostic (1.77e-2)" "unprognostic (2.96e-1)" "unprognostic (1.62e-1)" "potential prognostic unfavorable (1.72e-4)" "unprognostic (8.34e-2)" "unprognostic (1.13e-1)" "unprognostic (4.79e-2)" "unprognostic (9.46e-2)" "unprognostic (8.69e-2)" "unprognostic (2.82e-1)" "unprognostic (6.70e-3)" "unprognostic (3.22e-1)" "unprognostic (1.43e-1)" HTATSF1 TAT-SF1 ENSG00000102241 "HIV-1 Tat specific factor 1" O43719 X 136497079-136512346 "Essential proteins, Predicted intracellular proteins" "DNA damage, DNA repair, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Activator, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adrenal medulla cells: 170.2;Lactotrophs: 324.9;Somatotrophs: 285.2;Thyrotrophs: 283.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Minor Salivary Gland - Endothelial cells, Pituitary gland - Lactotropes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000504 Supported Enhanced Nucleoplasm NA NA 3500 "Cluster 3: Non-specific - Nuclear processes" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 36: Non-specific - mRNA processing" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 41 Nucleoplasm "HPA000504: " "unprognostic (3.31e-2)" "unprognostic (1.24e-2)" "unprognostic (1.81e-1)" "unprognostic (2.51e-1)" "unprognostic (1.20e-1)" "unprognostic (1.16e-1)" "unprognostic (5.58e-2)" "potential prognostic favorable (4.00e-4)" "unprognostic (1.45e-1)" "unprognostic (9.42e-3)" "potential prognostic favorable (3.33e-7)" "unprognostic (4.17e-2)" "unprognostic (2.87e-3)" "unprognostic (6.67e-3)" "unprognostic (1.13e-3)" "unprognostic (6.00e-2)" "unprognostic (9.98e-2)" "unprognostic (2.14e-1)" "unprognostic (6.90e-2)" "unprognostic (2.55e-1)" "unprognostic (1.21e-1)" "unprognostic (5.10e-2)" "unprognostic (1.49e-1)" "unprognostic (1.12e-1)" "unprognostic (5.03e-2)" "unprognostic (1.72e-1)" "unprognostic (6.94e-2)" "unprognostic (8.17e-2)" "unprognostic (1.85e-1)" "unprognostic (2.10e-2)" "unprognostic (4.58e-2)" HTD2 ENSG00000255154 "Hydroxyacyl-thioester dehydratase type 2" P86397 3 58306262-58320193 "Enzymes, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 41.0" "Group enriched" "Detected in some" 13 "Astrocytes: 9.1;Bergmann glia: 10.9;Brain excitatory neurons: 13.6;Brain inhibitory neurons: 12.1;Choroid plexus epithelial cells: 11.7;Ependymal cells: 6.7;Microglia: 5.6;Oligodendrocyte progenitor cells: 9.8;Oligodendrocytes: 9.2;Other brain neurons: 12.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066812, HPA077228" Approved Supported Nucleoli,Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 31: Non-specific - Transcription" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 22: Non-specific - Basic cellular functions" Mitochondria Nucleoli "HPA066812: , HPA077228: " "unprognostic (4.88e-1)" "unprognostic (1.70e-1)" "unprognostic (1.99e-1)" "unprognostic (4.94e-2)" "unprognostic (1.81e-1)" "unprognostic (1.06e-1)" "unprognostic (1.57e-1)" "unprognostic (1.25e-2)" "validated prognostic favorable (3.46e-5)" "validated prognostic favorable (8.11e-5)" "unprognostic (7.87e-3)" "unprognostic (3.36e-2)" "unprognostic (4.64e-2)" "unprognostic (3.03e-2)" "unprognostic (2.34e-1)" "unprognostic (2.49e-2)" "unprognostic (8.60e-3)" "unprognostic (1.22e-2)" "unprognostic (1.80e-1)" "unprognostic (2.26e-1)" "unprognostic (4.39e-2)" "unprognostic (1.36e-3)" "unprognostic (3.43e-1)" "unprognostic (1.19e-1)" "unprognostic (3.12e-1)" "unprognostic (1.61e-1)" "unprognostic (8.77e-2)" "unprognostic (1.88e-1)" HTN1 HIS1 ENSG00000126550 "Histatin 1" P15515 4 70050438-70058848 "Predicted secreted proteins, Transporters" Biomineralization "Antibiotic, Antimicrobial, Fungicide" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 2599 "salivary gland: 45682.2" "Group enriched" "Detected in some" 13 "Salivary acinar cells: 23935.2;Salivary myoepithelial cells: 8485.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 23 "skin cancer: 2.3" HPA077315 Approved "Secreted to digestive system" Defense NA NA "Cluster 82: Salivary gland - Secretion" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 2 "HPA077315: " "unprognostic (3.50e-2)" HTN3 HIS2 ENSG00000205649 "Histatin 3" P15516 4 70028455-70036538 "Predicted secreted proteins, Transporters" "Biomineralization, Immunity, Innate immunity" "Antibiotic, Antimicrobial, Fungicide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 1097 "salivary gland: 127659.8" "Group enriched" "Detected in some" 11 "Salivary acinar cells: 65692.5;Salivary myoepithelial cells: 29550.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Uterine cancer: 3.8" CAB073541 Enhanced "Secreted to digestive system" Immunity NA NA "Cluster 82: Salivary gland - Secretion" "Cluster 9: Non-specific - Receptor signaling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 2 "CAB073541: " "unprognostic (2.95e-2)" "unprognostic (1.15e-1)" "unprognostic (3.45e-3)" "unprognostic (1.21e-1)" "unprognostic (5.76e-1)" HTR1A "5-HT1A, ADRB2RL1, ADRBRL1" ENSG00000178394 "5-hydroxytryptamine receptor 1A" P08908 5 63957874-63962507 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Behavior "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 6.1" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "hippocampal CA1-3: 1.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 17 "Rhabdoid: 8.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA018073 Uncertain NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 1: Neuronal - Visual perception" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 6 "HPA018073: " HTR1B "5-HT1B, 5-HT1DB, HTR1D2, S12" ENSG00000135312 "5-hydroxytryptamine receptor 1B" P28222 6 77460924-77463491 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" Behavior "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "blood vessel: 7.5;brain: 2.6;placenta: 6.3;stomach 1: 4.7" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 10.6;Brain inhibitory neurons: 1.6;Corticotrophs: 1.6;Foveolar cells: 2.7;Gastric progenitor cells: 2.6;Gonadotrophs: 1.2;Mucous neck cells: 1.9;Retinal ganglion cells: 3.9;Sertoli cells: 1.1;Vascular smooth muscle cells: 3.7" "Cell type enhanced" "Detected in some" "endothelial cell: 4.7;medium spiny neuron: 4.3" "Cancer enhanced" "Detected in single" "Testicular Germ Cell Tumor (TCGA): 1.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Adrenocortical cancer: 8.0" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Lung - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Thyroid gland - Smooth muscle cells" "Region enriched" "Detected in all" 4 "basal ganglia: 38.6" "Region enhanced" "Detected in many" "basal ganglia: 12.0" HPA028808 Enhanced Approved "Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 62: Smooth muscle cells - Muscle contraction" 43 "Plasma membrane" "Endoplasmic reticulum" "HPA028808: " "unprognostic (1.82e-2)" "unprognostic (1.86e-1)" "unprognostic (5.19e-2)" HTR1D "5-HT1D, HT1DA, HTRL, RDC4" ENSG00000179546 "5-hydroxytryptamine receptor 1D" P28221 1 23191895-23217502 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 6.2;intestine: 8.0" "Cell type enhanced" "Detected in some" "Brain inhibitory neurons: 1.9;Cholangiocytes: 4.0;Early spermatids: 2.4;Endometrial glandular cells: 1.7;Enteric transient amplifying cells: 1.6;Enterocytes: 10.0;Prostatic club cells: 5.2;Respiratory deuterosomal cells: 2.1" "Cell type enhanced" "Detected in some" "eccentric medium spiny neuron: 8.1;medium spiny neuron: 6.1" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "midbrain: 25.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 10.6" "Colon - Colon enteroendocrine cells, Testis - Early spermatids, Testis - Late spermatids" NA NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 1: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 1: Enterocytes - Absorption and Digestion" "unprognostic (7.51e-3)" "unprognostic (5.79e-3)" "unprognostic (3.70e-2)" "unprognostic (1.31e-1)" "unprognostic (5.36e-3)" "unprognostic (2.03e-2)" "unprognostic (1.23e-3)" "potential prognostic unfavorable (3.72e-9)" "potential prognostic unfavorable (1.04e-4)" "unprognostic (2.23e-3)" "potential prognostic unfavorable (2.09e-4)" "unprognostic (1.40e-1)" "unprognostic (7.36e-3)" "unprognostic (2.67e-1)" "unprognostic (8.56e-2)" "unprognostic (2.15e-1)" HTR1E 5-HT1E ENSG00000168830 "5-hydroxytryptamine receptor 1E" P28566 6 86937528-87016679 "FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.5;ovary: 4.0" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 89.0;Brain inhibitory neurons: 106.9;Early spermatids: 46.3;Gastric chief cells: 66.6;Late primary spermatocytes: 78.1;Late spermatids: 51.0;Mucous neck cells: 39.7;Other brain neurons: 115.0;Ovarian stromal cells: 22.6;Parietal cells: 24.8" "Cell type enhanced" "Detected in many" "mammillary body: 325.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "Neuroblastoma: 2.3" "Colon - Colon enteroendocrine cells, Prostate - Fibroblasts, Stomach - Chief cells" "Low region specificity" "Detected in many" HPA004931 Approved NA NA "Cluster 65: Brain - Transcription" "Cluster 53: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 3 "HPA004931: " "unprognostic (1.23e-3)" HTR1F "5-HT1F, HTR1EL" ENSG00000179097 "5-hydroxytryptamine receptor 1F" P30939 3 87792706-87993839 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 1.7;retina: 3.3" "Cell type enhanced" "Detected in many" "Hematopoietic stem cells: 3589.7;Lactotrophs: 1047.5;Megakaryocyte progenitors: 693.0;Megakaryocyte-Erythroid progenitors: 1766.4;Pancreatic islet cells: 277.2;Pericytes: 314.5;Thymocytes: 342.2" "Cell type enhanced" "Detected in many" "pericyte: 44.6;vascular associated smooth muscle cell: 21.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 1.4;Leukemia: 1.3;thyroid cancer: 1.8" "Pituitary gland - Lactotropes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA005555 Uncertain NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 42: Retina - Visual perception" "Cluster 53: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" "HPA005555: " "unprognostic (1.19e-1)" "unprognostic (3.95e-1)" HTR2A "5-HT2A, HTR2" ENSG00000102468 "5-hydroxytryptamine receptor 2A" P28223 13 46831546-46897076 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "Behavior, Host-virus interaction" "G-protein coupled receptor, Host cell receptor for virus entry, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "blood vessel: 5.4;brain: 18.2" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 45.5;Brain inhibitory neurons: 35.2;Choroid plexus epithelial cells: 69.5;Decidual stromal cells: 11.4;Endometrial stromal cells: 11.7;Megakaryocytes: 24.7;Other brain neurons: 28.0" "Cell type enhanced" "Detected in many" "mammillary body: 206.5" "Cancer enhanced" "Detected in single" "Glioblastoma Multiforme (TCGA): 1.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Bile duct cancer: 2.6" "Prostate - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014011 Enhanced NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 109: Neurons - Neuronal signaling" 5 "HPA014011: " "unprognostic (6.03e-2)" "unprognostic (2.00e-1)" "unprognostic (2.34e-2)" "unprognostic (1.87e-2)" HTR2B "5-HT(2B), 5-HT2B" ENSG00000135914 "5-hydroxytryptamine receptor 2B" P41595 2 231108230-231125042 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" Behavior "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 17.2;cervix: 20.2;endometrium 1: 17.6;smooth muscle: 15.7" "Cell type enhanced" "Detected in many" "Adipocytes: 33.3;Cardiomyocytes: 72.0;Decidual stromal cells: 64.3;Endometrial stromal cells: 19.7;Epicardial cells: 88.7;Fibro-adipogenic progenitors: 17.3;Myonuclei: 38.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 6.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 15 "basophil: 1.9;T-reg: 1.0" "Group enriched" "Detected in many" 15 "granulocytes: 1.9;T-cells: 1.0" "Group enriched" "Detected in some" 7 "Rhabdoid: 18.6;skin cancer: 13.6" "Adrenal gland - Adrenal cortex cells, Kidney - Fibroblasts, Stomach - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA012867, HPA063658" Enhanced Supported Nucleoplasm NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 5: Rhabdoid - Unknown function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 3 Nucleoplasm "HPA012867: , HPA063658: " "unprognostic (6.89e-2)" "unprognostic (6.66e-2)" "unprognostic (5.64e-2)" "unprognostic (1.45e-1)" "unprognostic (1.51e-3)" "unprognostic (5.74e-3)" "unprognostic (5.21e-2)" "unprognostic (1.46e-2)" "unprognostic (3.64e-2)" "unprognostic (3.67e-3)" "unprognostic (2.10e-2)" "unprognostic (2.40e-1)" "unprognostic (9.58e-2)" "potential prognostic unfavorable (7.27e-4)" "unprognostic (1.51e-1)" "potential prognostic favorable (4.91e-4)" "potential prognostic favorable (3.86e-4)" "unprognostic (2.97e-2)" "potential prognostic unfavorable (5.04e-5)" "unprognostic (4.35e-2)" HTR2C "5-HT2C, 5HTR2C, HTR1C" ENSG00000147246 "5-hydroxytryptamine receptor 2C" P28335 X 114584078-114910061 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" Behavior "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 151 "brain: 28.2;choroid plexus: 104.4" "Cell type enriched" "Detected in some" 27 "Choroid plexus epithelial cells: 18809.0" "Cell type enriched" "Detected in all" 6 "choroid plexus epithelial cell: 14796.7" "Cancer enhanced" "Detected in single" "Testicular Germ Cell Tumor (TCGA): 1.6" "Region enriched" "Detected in all" 12 "choroid plexus: 620.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 3.5;Myeloma: 2.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 22 "unprognostic (1.04e-1)" HTR3A "5-HT3A, 5-HT3R, HTR3" ENSG00000166736 "5-hydroxytryptamine receptor 3A" P46098 11 113975075-113990313 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 2.3;intestine: 2.0;lymphoid tissue: 7.5;pancreas: 2.7;salivary gland: 4.8" "Cell type enhanced" "Detected in some" "B-cells: 5.5;Brain inhibitory neurons: 2.6;cDC: 2.4;Pancreatic acinar cells: 5.5;pDCs: 2.1;Salivary acinar cells: 2.9;Salivary myoepithelial cells: 1.9;Submucosal glandular cells: 1.1" "Cell type enriched" "Detected in some" 4 "CGE interneuron: 12.4" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 25.6" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 15 "memory B-cell: 3.9;naive B-cell: 13.9;plasmacytoid DC: 11.6" "Group enriched" "Detected in many" 128 "B-cells: 13.9;dendritic cells: 11.6" "Group enriched" "Detected in some" 9 "lymphoma: 15.4;Neuroblastoma: 12.9" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 12 "amygdala: 2.7;cerebral cortex: 4.1;hippocampal formation: 3.9" HPA069442 Supported NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 51: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 3 "HPA069442: " "unprognostic (6.38e-3)" "unprognostic (3.64e-3)" "unprognostic (1.87e-2)" "potential prognostic unfavorable (8.16e-4)" "unprognostic (3.60e-1)" "unprognostic (7.91e-2)" "unprognostic (2.80e-1)" "unprognostic (6.92e-2)" "unprognostic (9.05e-3)" "unprognostic (1.13e-2)" "unprognostic (8.34e-2)" "unprognostic (4.88e-2)" HTR3B 5-HT3B ENSG00000149305 "5-hydroxytryptamine receptor 3B" O95264 11 113904796-113949079 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "brain: 3.9" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 3.2;Epididymal clear cells: 2.0;Esophageal apical cells: 9.2;Platelets: 2.8;Renal collecting duct intercalated cells: 10.4;Sertoli cells: 2.2" "Cell type enhanced" "Detected in some" "deep-layer intratelencephalic: 6.5;upper-layer intratelencephalic: 20.8" "Cancer enhanced" "Detected in single" "Kidney Chromophobe (TCGA): 1.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in single" 8 "Neuroblastoma: 2.9" "Colon - Colon enteroendocrine cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA039559 Approved NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" 1 "HPA039559: " "unprognostic (6.23e-2)" "unprognostic (3.64e-2)" "unprognostic (2.59e-2)" HTR3C ENSG00000178084 "5-hydroxytryptamine receptor 3C" Q8WXA8 3 184053047-184060673 "FDA approved drug targets, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "lung: 2.3" "Cell type enriched" "Detected in some" 40 "Tuft cells: 184.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Uterine Corpus Endometrial Carcinoma (TCGA): 0.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 13: Lung - Secretion" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 95: Tuft cells - Chemosensory signaling" 1 HTR3D ENSG00000186090 "5-hydroxytryptamine receptor 3D" Q70Z44 3 184031544-184039369 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 31: Non-specific - Antiviral immune response" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 1 HTR3E ENSG00000186038 "5-hydroxytryptamine receptor 3E" A5X5Y0 3 184097064-184106995 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 56 "Tuft cells: 438.1" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in single" "Uterine Corpus Endometrial Carcinoma (TCGA): 0.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA049764 Enhanced NA NA "Cluster 9: Non-specific - Receptor signaling" "Cluster 24: Non-specific - Unknown function" "Cluster 95: Tuft cells - Chemosensory signaling" "HPA049764: " "unprognostic (4.56e-1)" HTR4 5-HT4 ENSG00000164270 "5-hydroxytryptamine receptor 4" Q13639 5 148446042-148677235 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 2.1;heart muscle: 4.3;intestine: 8.5" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 91.2;Brain inhibitory neurons: 187.7;Cardiomyocytes: 359.4;Enteric stem cells: 130.6;Enteric transient amplifying cells: 98.8;Enterocytes: 99.3;Lactotrophs: 116.9;Myosatellite cells: 91.5;Paneth cells: 170.2" "Cell type enhanced" "Detected in many" "hippocampal dentate gyrus: 298.5;mammillary body: 292.7;medium spiny neuron: 469.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "Rhabdoid: 2.1" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal cortex cells, Pituitary gland - Lactotropes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA040591 Enhanced NA NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 51: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" 6 "HPA040591: " "unprognostic (8.76e-2)" "unprognostic (3.37e-2)" HTR5A 5-HT5A ENSG00000157219 "5-hydroxytryptamine receptor 5A" P47898 7 155070324-155087392 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 5 "brain: 4.0" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 10.3;Brain inhibitory neurons: 9.6;Early spermatids: 7.9;Late primary spermatocytes: 8.7;Late spermatids: 21.6;Other brain neurons: 12.7;Retinal amacrine cells: 3.5;Retinal bipolar cells: 3.2" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enteroendocrine cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" CAB017467 Approved NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 2: Neurons - Nucleosome" "Cluster 11: Neuronal - Sensory perception" "Cluster 98: Neurons - Neurotransmission & signaling" "CAB017467: " "unprognostic (4.73e-2)" HTR6 "5-HT6, 5-HT6R" ENSG00000158748 "5-hydroxytryptamine receptor 6" P50406 1 19664875-19680966 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 14 "brain: 7.0" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 1.4;Brain inhibitory neurons: 5.3;Differentiating spermatogonia: 1.2;Early primary spermatocytes: 1.1;Epicardial cells: 2.3;Other brain neurons: 1.3;Retinal amacrine cells: 1.8" "Cell type enhanced" "Detected in many" "medium spiny neuron: 15.5" "Cancer enhanced" "Detected in single" "Kidney Renal Clear Cell Carcinoma (TCGA): 2.3" "Region enhanced" "Detected in many" "basal ganglia: 22.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 2.0;Rhabdoid: 3.2" "Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in many" HPA068165 Uncertain NA NA "Cluster 11: T-cells - Unknown function" "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" 12 "HPA068165: " "unprognostic (7.33e-2)" "unprognostic (1.62e-1)" HTR7 5-HT7 ENSG00000148680 "5-hydroxytryptamine receptor 7" P34969 10 90740823-90858039 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, RAS pathway related proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "parathyroid gland: 12.3;testis: 8.2" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 23.4;Brain inhibitory neurons: 19.7;cDC: 42.1;Hepatic stellate cells: 45.2;Hofbauer cells: 15.0;Late primary spermatocytes: 21.6;Macrophages: 30.1;monocytes: 16.0;Other brain neurons: 25.0;Undifferentiated spermatogonia: 25.7" "Cell type enhanced" "Detected in many" "LAMP5-LHX6 and Chandelier: 134.7;mammillary body: 335.5" "Group enriched" "Detected in some" 4 "Bladder Urothelial Carcinoma (TCGA): 3.1;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 2.5;Head and Neck Squamous Cell Carcinoma (TCGA): 5.0;Lung Squamous Cell Carcinoma (TCGA): 2.5;Testicular Germ Cell Tumor (TCGA): 1.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 12 "myeloid DC: 1.4" "Lineage enriched" "Detected in single" 12 "dendritic cells: 1.4" "Low cancer specificity" "Detected in many" "Adrenal gland - Macrophages, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA065367, HPA073617, CAB080587" Approved Supported Supported "Nucleoplasm,Vesicles,Plasma membrane,Primary cilium" NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 109: Neurons - Neuronal signaling" 1 "Nucleoplasm, Plasma membrane" "Vesicles, Primary cilium" "CAB080587: , HPA065367: , HPA073617: " "unprognostic (1.43e-1)" "unprognostic (3.78e-2)" "unprognostic (1.54e-3)" "unprognostic (8.63e-2)" "unprognostic (1.48e-2)" "unprognostic (9.57e-2)" "unprognostic (1.76e-1)" "unprognostic (1.58e-2)" "unprognostic (3.13e-2)" "unprognostic (1.50e-1)" HTRA1 "ARMD7, HtrA, IGFBP5-protease, PRSS11" ENSG00000166033 "HtrA serine peptidase 1" Q92743 10 122458551-122514907 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding, Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 751.4" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 291.5;Microglia: 310.8;Müller glia: 431.4;Oligodendrocyte progenitor cells: 316.1;Podocytes: 616.6;Retinal horizontal cells: 530.9;Retinal pigment epithelial cells: 268.6;Schwann cells: 270.3" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 348.6;oligodendrocyte: 220.5;oligodendrocyte precursor cell: 347.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Breast - Fibroblasts, Kidney - Podocytes, Lung - Fibroblasts_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Spleen - Fibroblasts_2, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036655 Approved Supported "Plasma membrane" "Secreted to blood" Enzyme NA NA 24800000 4200000 "Cluster 65: Brain - Transcription" "Cluster 19: Astrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 4 "Plasma membrane" "HPA036655: " "unprognostic (1.60e-2)" "unprognostic (3.01e-1)" "unprognostic (2.79e-1)" "unprognostic (2.21e-2)" "unprognostic (2.62e-2)" "unprognostic (2.07e-2)" "unprognostic (2.71e-2)" "unprognostic (8.97e-2)" "unprognostic (3.88e-3)" "unprognostic (2.44e-2)" "unprognostic (1.05e-1)" "unprognostic (1.16e-1)" "unprognostic (5.87e-2)" "unprognostic (7.90e-2)" "unprognostic (1.83e-3)" "unprognostic (2.44e-1)" "unprognostic (3.59e-2)" "unprognostic (1.54e-1)" "unprognostic (5.65e-2)" "unprognostic (1.03e-2)" "unprognostic (5.16e-3)" "unprognostic (9.94e-2)" "unprognostic (1.00e-1)" "unprognostic (1.56e-1)" "unprognostic (1.90e-1)" "unprognostic (2.31e-2)" "unprognostic (3.01e-2)" "potential prognostic unfavorable (5.15e-4)" "unprognostic (1.07e-1)" "unprognostic (3.34e-2)" "unprognostic (3.51e-1)" HTRA2 "OMI, PARK13, PRSS25" ENSG00000115317 "HtrA serine peptidase 2" O43464 2 74529596-74533350 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins" Apoptosis "Hydrolase, Protease, Serine protease" "Disease variant, Epilepsy, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 68.8;Late spermatids: 68.0;Megakaryocytes: 111.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004004, HPA006602, HPA027366" Uncertain Supported Mitochondria NA NA 180000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 24: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 67: Plasma cells - Plasma cell differentiation" 101 Mitochondria "CAB004004: , HPA006602: , HPA027366: " "unprognostic (2.08e-2)" "unprognostic (1.68e-1)" "unprognostic (2.84e-1)" "unprognostic (1.35e-1)" "unprognostic (2.53e-1)" "unprognostic (1.64e-1)" "unprognostic (3.69e-2)" "potential prognostic favorable (3.92e-4)" "unprognostic (1.32e-1)" "unprognostic (1.99e-1)" "potential prognostic favorable (3.18e-8)" "unprognostic (2.06e-2)" "unprognostic (4.65e-2)" "validated prognostic unfavorable (1.17e-5)" "validated prognostic unfavorable (3.97e-7)" "unprognostic (2.29e-1)" "unprognostic (6.65e-2)" "unprognostic (7.88e-3)" "unprognostic (4.80e-2)" "unprognostic (1.04e-1)" "unprognostic (1.53e-1)" "unprognostic (2.97e-1)" "unprognostic (3.59e-3)" "unprognostic (4.73e-2)" "unprognostic (1.12e-2)" "unprognostic (1.10e-1)" "unprognostic (1.66e-2)" "unprognostic (9.78e-2)" "unprognostic (2.38e-1)" "unprognostic (1.80e-1)" "unprognostic (1.24e-1)" HTRA3 "Prsp, Tasp" ENSG00000170801 "HtrA serine peptidase 3" P83110 4 8269754-8307098 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 190.8" "Cell type enhanced" "Detected in some" "Fibro-adipogenic progenitors: 70.6;Fibroblasts: 116.2;Hepatic stellate cells: 19.4;Leydig cells: 47.9;Myosatellite cells: 92.9;Neutrophil progenitors: 23.4;Ovarian stromal cells: 38.9;Peritubular myoid cells: 44.1;Smooth muscle cells: 24.7" "Cell type enriched" "Detected in some" 6 "fibroblast: 15.3" "Cancer enhanced" "Detected in all" "Pancreatic Adenocarcinoma (TCGA): 129.9" "Region enhanced" "Detected in many" "choroid plexus: 9.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 26.5" "Pancreas - Fibroblasts, Prostate - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "spinal cord: 13.5" "HPA021187, HPA063810" Approved Approved Vesicles "Secreted in other tissues" Enzyme NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 36: Choroid plexus - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 108: Fibroblasts - ECM organization" 6 Vesicles "HPA021187: , HPA063810: " "unprognostic (3.12e-2)" "unprognostic (5.19e-2)" "unprognostic (3.51e-1)" "unprognostic (1.70e-2)" "unprognostic (8.43e-3)" "unprognostic (2.16e-1)" "unprognostic (4.34e-2)" "unprognostic (9.31e-3)" "unprognostic (1.46e-2)" "potential prognostic unfavorable (2.49e-4)" "unprognostic (1.27e-1)" "unprognostic (5.71e-3)" "potential prognostic unfavorable (3.27e-5)" "potential prognostic unfavorable (5.44e-4)" "unprognostic (2.03e-1)" "unprognostic (7.36e-2)" "potential prognostic unfavorable (4.64e-4)" "unprognostic (8.19e-2)" "unprognostic (6.45e-2)" "unprognostic (4.73e-3)" "unprognostic (3.28e-2)" "unprognostic (6.61e-2)" "unprognostic (3.56e-2)" "unprognostic (1.78e-1)" "unprognostic (7.36e-2)" "unprognostic (1.03e-2)" "unprognostic (4.27e-2)" "potential prognostic unfavorable (3.99e-4)" "unprognostic (6.94e-2)" "potential prognostic unfavorable (2.51e-4)" "unprognostic (2.66e-1)" HTRA4 FLJ90724 ENSG00000169495 "HtrA serine peptidase 4" P83105 8 38974228-38988663 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "placenta: 62.7" "Cell type enriched" "Detected in many" 15 "Extravillous trophoblasts: 813.2" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 3.8;hippocampal dentate gyrus: 5.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 11 "testis cancer: 8.8" "Region enhanced" "Detected in single" "hippocampal formation: 2.1" "Low region specificity" "Detected in all" HPA045402 Enhanced "Secreted in female reproductive system" Enzyme NA NA 11000 "Cluster 24: Non-specific - Transcription" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 9: Non-specific - Receptor signaling" "Cluster 34: Testis cancer - Unknown function" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 12 "HPA045402: " "unprognostic (8.68e-2)" "unprognostic (1.96e-1)" "unprognostic (2.55e-1)" "unprognostic (2.52e-1)" "unprognostic (3.18e-3)" "unprognostic (7.57e-2)" "unprognostic (2.26e-2)" "unprognostic (6.44e-2)" "potential prognostic favorable (2.29e-4)" "unprognostic (1.39e-2)" "unprognostic (4.48e-1)" "unprognostic (1.49e-1)" "unprognostic (7.14e-2)" "unprognostic (3.15e-1)" "unprognostic (1.84e-3)" "unprognostic (1.36e-1)" "unprognostic (5.47e-3)" HTT "HD, IT15" ENSG00000197386 Huntingtin P42858 4 3041363-3243957 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Disease variant, Intellectual disability, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 349.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002756, HPA026114, HPA051524" Approved Supported Nucleoplasm,Cytosol NA NA 470000 "Cluster 33: Non-specific - ATP binding" "Cluster 27: Cerebellum - Synaptic function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 17: Non-specific - RNA processing" 758 Nucleoplasm Cytosol "CAB002756: , HPA026114: , HPA051524: " "unprognostic (1.48e-1)" "unprognostic (4.92e-2)" "unprognostic (2.96e-1)" "unprognostic (3.90e-1)" "unprognostic (1.04e-2)" "unprognostic (3.83e-1)" "unprognostic (1.29e-1)" "unprognostic (9.85e-2)" "unprognostic (3.44e-3)" "unprognostic (2.14e-2)" "validated prognostic favorable (1.88e-7)" "validated prognostic favorable (9.34e-4)" "unprognostic (2.15e-3)" "unprognostic (9.08e-3)" "unprognostic (1.17e-1)" "unprognostic (6.04e-2)" "unprognostic (9.58e-3)" "unprognostic (7.79e-3)" "unprognostic (6.08e-2)" "unprognostic (4.78e-2)" "unprognostic (3.79e-2)" "unprognostic (2.72e-2)" "unprognostic (4.18e-3)" "unprognostic (4.30e-2)" "unprognostic (1.05e-1)" "unprognostic (4.71e-2)" "unprognostic (2.21e-1)" "unprognostic (1.54e-1)" "unprognostic (4.64e-1)" "unprognostic (1.37e-1)" "unprognostic (1.92e-1)" HUNK ENSG00000142149 "Hormonally up-regulated Neu-associated kinase" P57058 21 31873020-32044633 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 9.2" "Cell type enhanced" "Detected in many" "Loop of henle epithelial cells: 84.8;Pancreatic duct cells: 83.4;Pituitary stem cells: 269.2;Renal collecting duct principal cells: 95.8;Renal connecting tubule cells: 233.0;Retinal amacrine cells: 202.1;Retinal pigment epithelial cells: 157.7" "Cell type enhanced" "Detected in many" "MGE interneuron: 145.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027232, HPA027295, HPA027372" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 53: Neurons - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" 5 "Nucleoplasm, Plasma membrane" "HPA027232: , HPA027295: , HPA027372: " "unprognostic (2.95e-2)" "unprognostic (1.08e-1)" "unprognostic (1.50e-1)" "unprognostic (2.62e-1)" "unprognostic (3.10e-1)" "unprognostic (1.08e-2)" "unprognostic (1.90e-1)" "unprognostic (1.79e-2)" "potential prognostic favorable (4.78e-6)" "unprognostic (7.49e-2)" "unprognostic (6.40e-3)" "unprognostic (9.49e-2)" "unprognostic (6.60e-2)" "unprognostic (3.31e-2)" "unprognostic (2.07e-1)" "unprognostic (1.83e-1)" "unprognostic (2.89e-3)" "unprognostic (4.01e-2)" "unprognostic (8.81e-2)" "unprognostic (5.71e-2)" "unprognostic (4.25e-1)" "unprognostic (1.85e-1)" "unprognostic (2.20e-1)" "unprognostic (1.72e-2)" "unprognostic (2.18e-1)" "unprognostic (1.92e-1)" "unprognostic (2.01e-2)" HUS1 ENSG00000136273 "HUS1 checkpoint clamp component" O60921 7 47963288-47979615 "Predicted intracellular proteins" "DNA damage" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 67.7;Late spermatids: 75.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026787, CAB080337" Approved Supported Nucleoplasm NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 76: Non-specific - Metabolism" "Cluster 6: Non-specific - Immune response" "Cluster 67: Non-specific - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 43 Nucleoplasm "CAB080337: , HPA026787: " "unprognostic (1.26e-1)" "unprognostic (6.80e-2)" "unprognostic (1.28e-1)" "potential prognostic unfavorable (2.34e-4)" "unprognostic (3.23e-1)" "unprognostic (9.33e-2)" "unprognostic (1.56e-3)" "unprognostic (1.20e-1)" "unprognostic (7.87e-3)" "unprognostic (1.30e-3)" "validated prognostic favorable (4.35e-5)" "validated prognostic favorable (7.03e-4)" "unprognostic (4.13e-1)" "potential prognostic unfavorable (1.90e-6)" "unprognostic (9.67e-2)" "unprognostic (6.18e-3)" "unprognostic (3.55e-2)" "unprognostic (7.01e-2)" "unprognostic (4.86e-2)" "unprognostic (3.06e-1)" "unprognostic (7.27e-2)" "unprognostic (1.81e-1)" "potential prognostic unfavorable (8.13e-4)" "unprognostic (1.30e-1)" "unprognostic (3.57e-1)" "unprognostic (7.67e-2)" "unprognostic (1.60e-1)" "unprognostic (1.24e-2)" "unprognostic (1.09e-1)" "unprognostic (9.80e-2)" "unprognostic (6.78e-2)" HUS1B ENSG00000188996 "HUS1 checkpoint clamp component B" Q8NHY5 6 655939-657100 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "testis: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Stomach - Fibroblasts" "Not detected" "Not detected" "HPA034511, HPA063449" Approved Nucleoplasm,Cytosol NA NA "Cluster 67: Testis - Mixed function" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 16: Thyroid cancer - Neuronal signaling" 15 Nucleoplasm Cytosol "HPA034511: , HPA063449: " "unprognostic (3.37e-1)" "unprognostic (9.21e-2)" HUWE1 "Ib772, KIAA0312, UREB1" ENSG00000086758 "HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1" Q7Z6Z7 X 53532096-53686752 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms, Differentiation, DNA damage, DNA repair, Ubl conjugation pathway" "DNA-binding, Transferase" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002548, CAB022718" Approved Supported "Nucleoplasm,Nuclear membrane,Cytosol,Mid piece,Principal piece,End piece" NA NA 130000 "Cluster 29: Non-specific - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 103: Non-specific - Basic cellular processes" 221 "Nucleoplasm, Cytosol" "Nuclear membrane, Mid piece, Principal piece, End piece" "CAB022718: , HPA002548: " "unprognostic (1.52e-1)" "unprognostic (1.16e-2)" "unprognostic (3.92e-1)" "unprognostic (2.25e-1)" "unprognostic (2.07e-1)" "unprognostic (8.06e-2)" "unprognostic (1.72e-1)" "unprognostic (2.50e-2)" "unprognostic (4.10e-1)" "unprognostic (8.99e-2)" "potential prognostic favorable (2.08e-5)" "unprognostic (1.45e-1)" "unprognostic (1.65e-1)" "unprognostic (1.26e-3)" "unprognostic (4.11e-2)" "unprognostic (3.97e-3)" "unprognostic (1.69e-3)" "unprognostic (1.77e-1)" "unprognostic (6.53e-3)" "unprognostic (2.06e-1)" "unprognostic (7.13e-2)" "unprognostic (2.49e-1)" "unprognostic (1.64e-1)" "unprognostic (6.89e-2)" "unprognostic (1.61e-1)" "unprognostic (1.88e-3)" "unprognostic (1.64e-1)" "unprognostic (2.01e-1)" "unprognostic (6.13e-2)" "unprognostic (1.43e-1)" "unprognostic (1.31e-1)" HVCN1 "Hv1, MGC15619, VSOP" ENSG00000122986 "Hydrogen voltage gated channel 1" Q96D96 12 110627841-110704950 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fertilization, Hydrogen ion transport, Immunity, Innate immunity, Ion transport, Transport" "Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "choroid plexus: 505.3" "Cell type enhanced" "Detected in many" "B-cells: 209.1;Cardiomyocytes: 105.0;Choroid plexus epithelial cells: 294.4;Early spermatids: 94.6;Late primary spermatocytes: 217.4;Late spermatids: 100.7;Oocytes: 368.4;pDCs: 118.4" "Cell type enriched" "Detected in all" 4 "choroid plexus epithelial cell: 264.6" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "choroid plexus: 319.2" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 14 "Leukemia: 33.4;lymphoma: 48.2;Myeloma: 30.4" "Adrenal gland - Macrophages, Lung - Macrophages, Prostate - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA039329 Enhanced NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 55: Lymphoma - Immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" "HPA039329: " "unprognostic (1.06e-1)" "unprognostic (6.35e-2)" "unprognostic (4.89e-2)" "unprognostic (1.27e-3)" "unprognostic (9.36e-3)" "unprognostic (2.05e-1)" "unprognostic (6.32e-3)" "potential prognostic unfavorable (1.80e-5)" "unprognostic (8.96e-2)" "unprognostic (4.24e-2)" "potential prognostic favorable (7.49e-4)" "unprognostic (1.07e-1)" "unprognostic (8.13e-2)" "unprognostic (1.31e-1)" "unprognostic (2.60e-2)" "unprognostic (8.18e-3)" "unprognostic (1.61e-1)" "unprognostic (1.84e-1)" "unprognostic (3.62e-1)" "unprognostic (2.84e-1)" "unprognostic (4.89e-1)" "unprognostic (6.68e-2)" "unprognostic (2.32e-1)" "unprognostic (7.84e-2)" "unprognostic (1.03e-1)" "unprognostic (7.81e-2)" "unprognostic (2.12e-1)" "unprognostic (1.79e-2)" "unprognostic (2.60e-1)" "unprognostic (2.77e-1)" "unprognostic (3.42e-1)" HYAL1 "HYAL-1, LUCA1" ENSG00000114378 "Hyaluronidase 1" Q12794 3 50299890-50312381 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Disease variant, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 197.5;lymphoid tissue: 93.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 30.5;Alveolar cells type 2: 31.4;Hepatocytes: 150.8;Lymphatic endothelial cells: 46.5;Vascular endothelial cells: 32.9" "Cell type enhanced" "Detected in all" "endothelial cell: 23.7" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 91.4;Liver Hepatocellular Carcinoma (TCGA): 70.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 3.3" "Lineage enriched" "Detected in single" 4 "granulocytes: 3.3" "Cancer enhanced" "Detected in many" "liver cancer: 17.4" "Colon - Endothelial cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Pituitary gland - Endothelial cells, Prostate - Endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002112 Uncertain "Secreted to blood" Enzyme NA NA 1600000 "Cluster 21: Neutrophils - Unknown function" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 18: Liver cancer - Metabolism" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "HPA002112: " "unprognostic (5.77e-2)" "unprognostic (1.77e-1)" "unprognostic (1.54e-1)" "unprognostic (1.63e-1)" "unprognostic (3.12e-3)" "unprognostic (2.21e-1)" "unprognostic (9.83e-2)" "unprognostic (2.58e-3)" "unprognostic (5.76e-2)" "unprognostic (1.37e-2)" "potential prognostic favorable (7.14e-10)" "unprognostic (4.24e-3)" "potential prognostic favorable (3.47e-4)" "unprognostic (1.84e-1)" "unprognostic (2.97e-1)" "unprognostic (8.13e-2)" "unprognostic (1.25e-1)" "unprognostic (1.44e-1)" "unprognostic (1.19e-1)" "unprognostic (7.29e-2)" "unprognostic (9.53e-3)" "unprognostic (1.47e-2)" "unprognostic (6.03e-3)" "unprognostic (1.10e-1)" "unprognostic (4.64e-2)" "unprognostic (6.86e-2)" "unprognostic (2.96e-2)" "unprognostic (5.90e-2)" "unprognostic (2.39e-1)" "unprognostic (1.12e-1)" "unprognostic (4.41e-2)" HYAL2 "LuCa-2, LUCA2" ENSG00000068001 "Hyaluronidase 2" Q12891 3 50317790-50322782 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 296.8" "Group enriched" "Detected in many" 4 "Lymphatic endothelial cells: 403.7;Vascular endothelial cells: 299.3" "Cell type enriched" "Detected in all" 7 "endothelial cell: 142.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Endothelial cells, Breast - Adipocytes (Breast), Colon - Endothelial cells, Liver - Vascular endothelial cells, Pancreas - Endothelial cells, Pituitary gland - Endothelial cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036436 Uncertain NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 43 "HPA036436: " "unprognostic (4.44e-1)" "unprognostic (1.26e-1)" "unprognostic (2.42e-2)" "unprognostic (6.64e-2)" "unprognostic (2.06e-1)" "unprognostic (2.95e-1)" "unprognostic (5.48e-2)" "unprognostic (1.45e-1)" "unprognostic (9.47e-2)" "unprognostic (6.48e-2)" "validated prognostic favorable (2.70e-7)" "validated prognostic favorable (1.22e-6)" "unprognostic (5.26e-3)" "unprognostic (2.75e-2)" "unprognostic (1.63e-1)" "unprognostic (3.06e-1)" "unprognostic (3.99e-2)" "unprognostic (5.49e-2)" "unprognostic (1.17e-1)" "unprognostic (3.04e-1)" "unprognostic (1.03e-1)" "unprognostic (1.36e-2)" "unprognostic (1.32e-1)" "unprognostic (3.04e-1)" "unprognostic (2.22e-1)" "unprognostic (6.60e-2)" "unprognostic (2.20e-1)" "unprognostic (7.16e-2)" "unprognostic (3.17e-1)" "unprognostic (1.53e-2)" "unprognostic (2.52e-2)" HYAL3 "LUCA-3, LUCA14, Minna14" ENSG00000186792 "Hyaluronidase 3" O43820 3 50292831-50299405 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" Fertilization "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 34.3" "Cell type enriched" "Detected in many" 4 "Late spermatids: 435.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 33.2;eosinophil: 54.7" "Lineage enriched" "Detected in all" 7 "granulocytes: 54.7" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA049402 Uncertain "Secreted to blood" Enzyme NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 37: Neurons - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 2 "HPA049402: " "unprognostic (5.47e-2)" "unprognostic (1.38e-2)" "unprognostic (3.53e-1)" "unprognostic (1.54e-3)" "unprognostic (1.07e-1)" "unprognostic (1.92e-1)" "unprognostic (5.75e-2)" "unprognostic (2.65e-2)" "unprognostic (2.37e-2)" "unprognostic (1.57e-1)" "unprognostic (1.28e-1)" "unprognostic (3.59e-3)" "unprognostic (1.68e-1)" "unprognostic (2.52e-3)" "unprognostic (2.00e-3)" "unprognostic (8.11e-3)" "unprognostic (1.02e-1)" "unprognostic (5.70e-2)" "unprognostic (3.86e-3)" "unprognostic (5.43e-2)" "unprognostic (3.67e-1)" "unprognostic (1.69e-1)" "unprognostic (2.20e-1)" "unprognostic (9.25e-2)" "unprognostic (3.14e-2)" "unprognostic (5.86e-2)" "unprognostic (5.60e-2)" "unprognostic (3.64e-2)" "unprognostic (5.98e-3)" "unprognostic (4.93e-2)" "unprognostic (1.07e-2)" HYAL4 ENSG00000106302 "Hyaluronidase 4" Q2M3T9 7 123828983-123877481 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 3.7;skeletal muscle: 3.8" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 19.3;Differentiating spermatogonia: 14.3;Early primary spermatocytes: 10.8;Epididymal clear cells: 42.9;Extravillous trophoblasts: 34.0;Migrating cytotrophoblasts: 15.8;Myonuclei: 97.5;Renal collecting duct intercalated cells: 49.3;Syncytiotrophoblasts: 9.5;Undifferentiated spermatogonia: 12.9" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "Testicular Germ Cell Tumor (TCGA): 15.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA029453 Uncertain NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 9: Non-specific - Receptor signaling" "Cluster 66: Non-specific - Mitochondria" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 1 "HPA029453: " "unprognostic (2.60e-1)" "unprognostic (2.54e-3)" "unprognostic (1.43e-1)" "unprognostic (1.70e-1)" HYCC1 "DRCTNNB1A, FAM126A, HCC, hyccin" ENSG00000122591 "Hyccin PI4KA lipid kinase complex subunit 1" Q9BYI3 7 22889371-23014130 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cataract, Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 252.8;Esophageal apical cells: 248.7;Melanocytes: 257.2;Pituicytes/FSCs: 570.7;Retinal pigment epithelial cells: 264.3;Schwann cells: 248.4" "Cell type enhanced" "Detected in all" "hippocampal CA4: 324.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Skin - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042873 Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 12 "Plasma membrane, Cytosol" "HPA042873: " "unprognostic (2.22e-3)" "unprognostic (6.70e-2)" "unprognostic (1.42e-1)" "unprognostic (8.24e-2)" "unprognostic (5.82e-3)" "unprognostic (1.88e-1)" "unprognostic (6.47e-2)" "potential prognostic unfavorable (1.65e-4)" "unprognostic (1.72e-2)" "unprognostic (2.71e-3)" "unprognostic (2.13e-1)" "unprognostic (1.36e-1)" "unprognostic (9.36e-2)" "potential prognostic unfavorable (6.47e-5)" "unprognostic (3.04e-2)" "unprognostic (1.97e-2)" "potential prognostic unfavorable (8.27e-4)" "unprognostic (2.66e-1)" "unprognostic (1.55e-1)" "unprognostic (1.27e-1)" "unprognostic (1.80e-2)" "unprognostic (2.85e-1)" "unprognostic (5.35e-2)" "unprognostic (1.52e-1)" "unprognostic (1.81e-1)" "unprognostic (3.14e-3)" "unprognostic (1.07e-2)" "unprognostic (3.78e-3)" "unprognostic (8.43e-2)" "unprognostic (4.15e-3)" "unprognostic (4.39e-2)" HYCC2 "FAM126B, MGC39518" ENSG00000155744 "Hyccin PI4KA lipid kinase complex subunit 2" Q8IXS8 2 200973718-201071671 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 494.9;Neutrophil progenitors: 295.5;Neutrophils: 1348.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "neutrophil: 25.9" "Lineage enriched" "Detected in all" 6 "granulocytes: 25.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036166, HPA036167, HPA067307" Uncertain Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 16: Non-specific - Transcription" "Cluster 20: Myeloma - Immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 6 "Cell Junctions" Nucleoplasm "HPA036166: , HPA036167: , HPA067307: " "unprognostic (1.29e-2)" "unprognostic (3.48e-3)" "unprognostic (1.28e-1)" "unprognostic (1.87e-1)" "unprognostic (1.14e-1)" "unprognostic (6.36e-2)" "unprognostic (2.51e-1)" "unprognostic (1.03e-2)" "unprognostic (8.44e-3)" "unprognostic (3.95e-2)" "potential prognostic favorable (2.14e-4)" "unprognostic (3.51e-3)" "unprognostic (3.88e-2)" "unprognostic (1.89e-2)" "unprognostic (3.74e-3)" "unprognostic (3.06e-3)" "unprognostic (3.47e-2)" "unprognostic (2.52e-1)" "unprognostic (1.77e-2)" "unprognostic (6.49e-2)" "potential prognostic unfavorable (5.17e-4)" "unprognostic (2.60e-3)" "unprognostic (9.10e-2)" "unprognostic (2.59e-2)" "unprognostic (1.03e-2)" "unprognostic (1.80e-1)" "unprognostic (8.68e-3)" "unprognostic (5.32e-2)" "unprognostic (2.51e-1)" "unprognostic (1.36e-2)" "unprognostic (1.15e-1)" HYDIN "CILD5, DKFZp434D0513, KIAA1864, PPP1R31" ENSG00000157423 "HYDIN axonemal central pair apparatus protein" Q4G0P3 16 70802084-71230722 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 5.0;retina: 6.3" "Group enriched" "Detected in many" 4 "Choroid plexus epithelial cells: 620.2;Endometrial ciliated cells: 524.9;Ependymal cells: 1646.9;Epididymal efferent duct ciliated cells: 529.2;Fallopian tube ciliated cells: 563.0;Respiratory ciliated cells: 1047.6" "Group enriched" "Detected in all" 5 "choroid plexus epithelial cell: 500.8;ependymal cell: 1758.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA046282, HPA067155" Enhanced Approved "Nucleoplasm,Cytokinetic bridge,Mitotic spindle,Primary cilium,Cytosol,Equatorial segment" Yes NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" 1 "Cytokinetic bridge, Primary cilium, Cytosol, Equatorial segment" "Nucleoplasm, Mitotic spindle" "HPA046282: , HPA067155: " "unprognostic (8.05e-2)" "unprognostic (3.63e-2)" "unprognostic (5.58e-2)" "unprognostic (4.23e-3)" "unprognostic (8.68e-2)" "unprognostic (1.29e-1)" "unprognostic (1.12e-2)" "potential prognostic unfavorable (2.10e-4)" "unprognostic (6.03e-2)" "unprognostic (6.93e-2)" HYI HT036 ENSG00000178922 "Hydroxypyruvate isomerase (putative)" Q5T013 1 43450989-43453989 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 204.7;Epididymal efferent duct absorptive cells: 131.6;Extravillous trophoblasts: 173.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 30.0" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in all" 4 "Adrenocortical cancer: 190.2" "Low region specificity" "Detected in all" HPA040092 Approved Approved "Golgi apparatus,Plasma membrane,Cytosol" No No "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 39: Astrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 1: Enterocytes - Absorption and Digestion" 5 "Plasma membrane, Cytosol" "Golgi apparatus" "HPA040092: " "unprognostic (5.32e-2)" "unprognostic (1.01e-3)" "unprognostic (7.38e-2)" "unprognostic (1.45e-1)" "unprognostic (5.15e-2)" "unprognostic (7.29e-2)" "unprognostic (2.77e-2)" "unprognostic (9.36e-3)" "unprognostic (2.68e-1)" "unprognostic (1.60e-1)" "potential prognostic favorable (9.65e-5)" "unprognostic (2.20e-1)" "unprognostic (5.78e-2)" "unprognostic (5.13e-3)" "unprognostic (3.50e-2)" "unprognostic (3.15e-2)" "unprognostic (2.63e-1)" "unprognostic (6.34e-3)" "unprognostic (3.65e-3)" "unprognostic (3.40e-2)" "unprognostic (7.29e-3)" "unprognostic (1.95e-1)" "unprognostic (3.59e-2)" "unprognostic (1.49e-1)" "unprognostic (4.68e-3)" "unprognostic (2.99e-1)" "unprognostic (8.93e-2)" "unprognostic (2.07e-1)" "unprognostic (2.22e-1)" "unprognostic (3.12e-2)" "unprognostic (2.60e-1)" HYKK "AGPHD1, LOC123688" ENSG00000188266 "Hydroxylysine kinase" A2RU49 15 78507564-78537372 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Enterocytes: 44.5;Late spermatids: 51.7;Myosatellite cells: 68.5;Respiratory basal cells: 33.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 3.0" "Lineage enriched" "Detected in single" 7 "T-cells: 3.0" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA040706 Approved Approved Nucleoplasm,Vesicles,Aggresome,Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 72: Kidney - Transmembrane transport" "Cluster 33: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 1: Enterocytes - Absorption and Digestion" 2 "Nucleoplasm, Vesicles, Aggresome, Cytosol" "HPA040706: " "unprognostic (1.30e-2)" "unprognostic (3.04e-3)" "unprognostic (4.75e-2)" "unprognostic (3.16e-2)" "unprognostic (1.08e-1)" "unprognostic (2.29e-1)" "unprognostic (6.96e-3)" "unprognostic (1.09e-1)" "unprognostic (4.81e-2)" "unprognostic (2.71e-2)" "unprognostic (7.33e-3)" "potential prognostic favorable (5.95e-4)" "unprognostic (7.84e-2)" "unprognostic (1.38e-1)" "unprognostic (1.73e-1)" "unprognostic (1.44e-2)" "unprognostic (5.66e-2)" "unprognostic (5.05e-2)" "unprognostic (2.88e-2)" "unprognostic (3.45e-2)" "unprognostic (7.68e-2)" "unprognostic (1.06e-1)" "unprognostic (2.96e-2)" "unprognostic (6.93e-2)" "unprognostic (2.01e-1)" "unprognostic (5.23e-1)" "unprognostic (2.86e-2)" "unprognostic (9.55e-3)" "unprognostic (1.54e-1)" HYLS1 FLJ32915 ENSG00000198331 "HYLS1 centriolar and ciliogenesis associated" Q96M11 11 125883614-125900646 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 24.8" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 67.7;Early spermatids: 136.4;Late primary spermatocytes: 119.1;Late spermatids: 82.5;Oocytes: 128.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041210 Enhanced Approved "Plasma membrane,Cytosol" NA Yes "Cluster 23: B-cells - Immunoglobulins" "Cluster 67: Testis - Mixed function" "Cluster 5: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 1 "Plasma membrane, Cytosol" "HPA041210: " "unprognostic (1.81e-1)" "unprognostic (1.08e-1)" "unprognostic (1.29e-1)" "unprognostic (3.72e-2)" "unprognostic (2.76e-1)" "unprognostic (5.25e-2)" "unprognostic (4.62e-3)" "unprognostic (2.46e-1)" "unprognostic (3.33e-2)" "unprognostic (1.69e-3)" "unprognostic (5.85e-3)" "unprognostic (1.31e-1)" "unprognostic (2.32e-1)" "potential prognostic unfavorable (2.21e-4)" "unprognostic (1.62e-2)" "unprognostic (7.20e-3)" "unprognostic (3.43e-2)" "unprognostic (1.18e-2)" "unprognostic (2.61e-1)" "unprognostic (1.55e-2)" "unprognostic (1.05e-1)" "unprognostic (1.24e-1)" "unprognostic (1.84e-1)" "unprognostic (1.86e-2)" "unprognostic (8.26e-2)" "unprognostic (1.97e-1)" "unprognostic (4.11e-3)" "unprognostic (8.51e-2)" "unprognostic (1.43e-1)" "unprognostic (6.17e-2)" "unprognostic (2.18e-2)" HYOU1 "Grp170, HSP12A, ORP150" ENSG00000149428 "Hypoxia up-regulated 1" Q9Y4L1 11 119044188-119057227 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Stress response" Chaperone "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Corticotrophs: 35.9;Early spermatids: 34.9;Late spermatids: 29.9;Other brain neurons: 30.0;Plasma cells: 36.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Macrophages, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049296 Approved "Intracellular and membrane" Other NA NA 59000000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 70: Non-specific - Protein processing" "Cluster 45: Non-specific - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 78: Plasma cells - Antibody production & ER-stress response" 54 "HPA049296: " "unprognostic (1.26e-1)" "unprognostic (2.72e-2)" "unprognostic (1.36e-2)" "unprognostic (5.35e-2)" "unprognostic (3.76e-2)" "unprognostic (1.32e-1)" "unprognostic (9.94e-2)" "unprognostic (3.81e-2)" "potential prognostic unfavorable (9.35e-4)" "unprognostic (7.80e-3)" "validated prognostic unfavorable (1.25e-5)" "validated prognostic unfavorable (9.86e-4)" "unprognostic (5.87e-2)" "unprognostic (2.28e-3)" "unprognostic (1.24e-2)" "unprognostic (1.25e-1)" "unprognostic (1.94e-2)" "unprognostic (1.71e-1)" "unprognostic (2.68e-1)" "unprognostic (3.02e-2)" "unprognostic (3.61e-1)" "unprognostic (9.29e-2)" "unprognostic (1.17e-1)" "unprognostic (4.52e-1)" "unprognostic (3.20e-2)" "unprognostic (1.22e-1)" "unprognostic (4.24e-2)" "unprognostic (8.16e-2)" "unprognostic (1.27e-2)" "unprognostic (1.05e-2)" "unprognostic (8.00e-2)" HYPK "C15orf63, FLJ20431, HSPC136" ENSG00000242028 "Huntingtin interacting protein K" Q9NX55 15 43796142-43804427 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 10 "Astrocytes: 19.8;Bergmann glia: 15.3;Brain excitatory neurons: 25.1;Brain inhibitory neurons: 23.5;Choroid plexus epithelial cells: 15.6;Ependymal cells: 17.8;Microglia: 13.7;Oligodendrocyte progenitor cells: 19.2;Oligodendrocytes: 28.3;Other brain neurons: 25.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055252 Uncertain Supported Nucleoplasm,Microtubules NA NA 15000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 58: Non-specific - Nuclear processes" "Cluster 98: Neurons - Neurotransmission & signaling" 29 Nucleoplasm Microtubules "HPA055252: " "unprognostic (1.45e-1)" "unprognostic (3.09e-2)" "unprognostic (1.12e-2)" "unprognostic (2.83e-2)" "unprognostic (5.78e-2)" "unprognostic (9.89e-2)" "unprognostic (9.96e-3)" "unprognostic (2.49e-2)" "potential prognostic unfavorable (8.27e-4)" "unprognostic (3.35e-3)" "unprognostic (1.58e-2)" "unprognostic (3.78e-2)" "unprognostic (3.65e-1)" "unprognostic (6.40e-3)" "unprognostic (6.31e-2)" "unprognostic (1.44e-1)" "unprognostic (3.78e-2)" "unprognostic (3.58e-1)" "unprognostic (1.45e-2)" "unprognostic (1.21e-1)" "unprognostic (1.01e-2)" "unprognostic (1.16e-1)" "unprognostic (3.40e-1)" "unprognostic (8.45e-3)" "unprognostic (4.31e-1)" "unprognostic (3.04e-1)" "unprognostic (1.69e-1)" "unprognostic (1.19e-1)" "unprognostic (1.31e-2)" IAH1 ENSG00000134330 "Isoamyl acetate hydrolyzing esterase 1 (putative)" Q2TAA2 2 9473658-9496543 "Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 419.8;Epicardial cells: 370.7;Late primary spermatocytes: 542.3;Late spermatids: 756.6;Oocytes: 718.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040523, HPA076040" Approved Approved Nucleoplasm NA NA 120000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 41: Oocytes - Oogenesis" Nucleoplasm "HPA040523: , HPA076040: " "unprognostic (5.14e-2)" "unprognostic (1.50e-1)" "unprognostic (3.50e-2)" "unprognostic (7.39e-3)" "unprognostic (1.08e-1)" "unprognostic (4.28e-1)" "unprognostic (7.29e-3)" "unprognostic (9.76e-2)" "unprognostic (3.67e-3)" "unprognostic (3.34e-3)" "unprognostic (1.91e-3)" "unprognostic (7.43e-3)" "unprognostic (2.20e-1)" "validated prognostic unfavorable (9.45e-4)" "validated prognostic unfavorable (8.87e-5)" "unprognostic (1.46e-1)" "unprognostic (1.11e-2)" "unprognostic (3.96e-3)" "unprognostic (9.88e-3)" "unprognostic (1.50e-1)" "unprognostic (2.65e-1)" "unprognostic (1.15e-2)" "unprognostic (1.93e-1)" "unprognostic (2.53e-2)" "unprognostic (1.62e-1)" "potential prognostic favorable (4.14e-4)" "unprognostic (1.91e-2)" "unprognostic (1.51e-1)" "unprognostic (1.43e-1)" "unprognostic (4.92e-2)" "unprognostic (4.18e-3)" IAPP "AMYLIN, DAP, IAP" ENSG00000121351 "Islet amyloid polypeptide" P10997 12 21354959-21379980 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 54 "pancreas: 157.0" "Cell type enriched" "Detected in some" 42 "Pancreatic islet cells: 1972.9" "Cell type enriched" "Detected in single" 5 "endothelial cell: 1.4" "Cancer enriched" "Detected in single" 40 "Pancreatic Adenocarcinoma (TCGA): 36.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 2.4;thyroid cancer: 1.6" "Pancreas - Beta cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "CAB000352, HPA053194" Enhanced Approved Vesicles "Secreted to blood" Hormone NA NA 606000 "Cluster 8: Pancreas - Proteolysis" "Cluster 48: Non-specific - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 2 Vesicles "CAB000352: , HPA053194: " "unprognostic (1.66e-1)" "unprognostic (6.95e-2)" IARS1 "IARS, ILRS" ENSG00000196305 "Isoleucyl-tRNA synthetase 1" P41252 9 92210207-92293854 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029806 Approved Approved Nucleoplasm,Cytosol NA NA 150000 "Cluster 24: Non-specific - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 17: Non-specific - RNA processing" 69 "Nucleoplasm, Cytosol" "HPA029806: " "unprognostic (2.27e-3)" "unprognostic (1.26e-2)" "unprognostic (1.39e-3)" "unprognostic (1.26e-1)" "unprognostic (3.24e-2)" "unprognostic (3.06e-1)" "unprognostic (1.44e-2)" "unprognostic (2.60e-1)" "unprognostic (8.96e-3)" "potential prognostic favorable (3.75e-7)" "unprognostic (3.86e-2)" "unprognostic (2.25e-1)" "unprognostic (2.32e-3)" "unprognostic (1.42e-2)" "unprognostic (2.10e-2)" "unprognostic (7.07e-2)" "unprognostic (2.43e-1)" "unprognostic (2.19e-2)" "unprognostic (1.78e-1)" "unprognostic (3.17e-3)" "unprognostic (1.16e-1)" "unprognostic (9.05e-2)" "potential prognostic favorable (3.86e-4)" "unprognostic (6.45e-3)" "unprognostic (2.31e-1)" "unprognostic (1.29e-1)" "unprognostic (1.09e-1)" "unprognostic (6.36e-2)" "unprognostic (1.17e-1)" IARS2 FLJ10326 ENSG00000067704 "Isoleucyl-tRNA synthetase 2, mitochondrial" Q9NSE4 1 220094132-220148041 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Cataract, Deafness, Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024212, HPA024594, HPA024596" Enhanced Enhanced Mitochondria NA NA 88000 "Cluster 33: Non-specific - ATP binding" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 45: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 32 Mitochondria "HPA024212: , HPA024594: , HPA024596: " "unprognostic (4.28e-2)" "unprognostic (1.29e-2)" "unprognostic (1.08e-1)" "potential prognostic unfavorable (7.99e-4)" "potential prognostic favorable (6.59e-4)" "unprognostic (8.25e-3)" "unprognostic (1.73e-1)" "unprognostic (3.29e-2)" "unprognostic (2.18e-1)" "unprognostic (1.50e-3)" "potential prognostic favorable (2.85e-6)" "unprognostic (1.52e-1)" "unprognostic (3.31e-2)" "unprognostic (9.39e-2)" "unprognostic (9.18e-2)" "unprognostic (1.03e-2)" "unprognostic (1.87e-2)" "unprognostic (7.51e-2)" "unprognostic (3.44e-1)" "unprognostic (5.89e-2)" "unprognostic (6.08e-3)" "potential prognostic unfavorable (5.18e-4)" "unprognostic (2.45e-1)" "unprognostic (3.87e-1)" "unprognostic (7.15e-2)" "unprognostic (1.35e-1)" "unprognostic (1.62e-1)" "unprognostic (3.51e-1)" "unprognostic (2.92e-1)" "unprognostic (2.11e-2)" "unprognostic (2.29e-1)" IBA57 "C1orf69, FLJ12734" ENSG00000181873 "Iron-sulfur cluster assembly factor IBA57" Q5T440 1 228165804-228182257 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Heme biosynthesis" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late spermatids: 48.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "HPA030555, HPA030556, HPA030557" Approved Supported Mitochondria NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 45: Non-specific - Nuclear processes" "Cluster 65: Non-specific - Cell growth & division" 6 Mitochondria "HPA030555: , HPA030556: , HPA030557: " "unprognostic (2.00e-2)" "unprognostic (2.71e-2)" "unprognostic (1.09e-1)" "unprognostic (2.43e-2)" "unprognostic (9.92e-2)" "unprognostic (1.50e-1)" "unprognostic (1.53e-1)" "unprognostic (5.26e-3)" "unprognostic (1.92e-1)" "validated prognostic favorable (1.09e-6)" "validated prognostic favorable (1.49e-5)" "unprognostic (1.52e-3)" "unprognostic (9.88e-2)" "unprognostic (2.52e-1)" "unprognostic (2.77e-1)" "unprognostic (3.03e-1)" "unprognostic (2.11e-1)" "unprognostic (1.02e-1)" "unprognostic (5.52e-2)" "unprognostic (1.37e-2)" "unprognostic (2.30e-2)" "unprognostic (1.87e-1)" "unprognostic (3.45e-1)" "unprognostic (7.60e-2)" "unprognostic (1.72e-1)" "unprognostic (1.03e-2)" "unprognostic (8.62e-3)" "unprognostic (1.83e-1)" "unprognostic (8.68e-3)" "unprognostic (4.75e-2)" IBSP "BSP, BSP-II, SP-II" ENSG00000029559 "Integrin binding sialoprotein" P21815 4 87799554-87812435 "Cancer-related genes, Predicted secreted proteins" "Biomineralization, Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "blood vessel: 2.5;pituitary gland: 1.9" "Cell type enhanced" "Detected in some" "Respiratory ciliated cells: 1.2;Schwann cells: 1.5" "Cell type enriched" "Detected in some" 4 "LAMP5-LHX6 and Chandelier: 7.3" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 19.3" "Region enhanced" "Detected in some" "thalamus: 4.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lymphoma: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA059068, HPA065857" Approved Nucleoplasm,Vesicles,Cytosol "Secreted in other tissues" "Cell adhesion" NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 12: Non-specific - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 109: Neurons - Neuronal signaling" 1 Vesicles "Nucleoplasm, Cytosol" "HPA059068: , HPA065857: " "unprognostic (1.42e-3)" "unprognostic (1.65e-1)" "unprognostic (7.09e-2)" "unprognostic (3.40e-2)" "unprognostic (2.10e-1)" "unprognostic (1.65e-2)" "unprognostic (8.30e-3)" "unprognostic (1.15e-2)" "potential prognostic unfavorable (4.83e-5)" "unprognostic (4.75e-2)" "unprognostic (1.75e-3)" "unprognostic (4.41e-3)" "unprognostic (9.22e-2)" "unprognostic (1.26e-1)" "unprognostic (1.28e-2)" "unprognostic (1.93e-1)" "unprognostic (1.76e-2)" "unprognostic (2.08e-3)" "unprognostic (1.26e-2)" "unprognostic (6.10e-3)" "unprognostic (4.86e-1)" "unprognostic (3.83e-2)" IBTK "BTBD26, BTKI, DKFZP564B116" ENSG00000005700 "Inhibitor of Bruton tyrosine kinase" Q9P2D0 6 82169986-82247754 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 119.2;Brain inhibitory neurons: 126.0;Choroid plexus epithelial cells: 142.4;Distal convoluted tubule cells: 117.2;Ependymal cells: 86.3;Loop of henle epithelial cells: 100.4;Microglia: 144.2;Oligodendrocyte progenitor cells: 105.0;Oligodendrocytes: 184.5;Other brain neurons: 111.4;Papillary tip epithelial cells: 82.1;Podocytes: 104.3;Proximal tubule cells: 83.0;Renal collecting duct intercalated cells: 107.8;Renal collecting duct principal cells: 94.7;Renal connecting tubule cells: 113.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023826, HPA048438" Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 76: Non-specific - Metabolism" "Cluster 55: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 102: Non-specific - Mixed function" 19 Nucleoplasm Cytosol "HPA023826: , HPA048438: " "unprognostic (1.83e-1)" "unprognostic (2.00e-2)" "unprognostic (2.44e-1)" "unprognostic (1.77e-2)" "unprognostic (4.02e-2)" "unprognostic (3.98e-2)" "unprognostic (2.37e-1)" "unprognostic (2.75e-2)" "unprognostic (8.70e-2)" "unprognostic (2.55e-2)" "potential prognostic favorable (5.42e-7)" "unprognostic (1.95e-2)" "unprognostic (1.14e-1)" "unprognostic (1.80e-1)" "unprognostic (3.07e-1)" "unprognostic (5.78e-2)" "unprognostic (1.36e-1)" "unprognostic (7.22e-3)" "unprognostic (1.16e-1)" "unprognostic (6.58e-2)" "potential prognostic unfavorable (9.41e-5)" "unprognostic (1.83e-2)" "unprognostic (1.47e-1)" "unprognostic (7.80e-2)" "unprognostic (5.79e-2)" "unprognostic (6.10e-2)" "unprognostic (7.65e-2)" "unprognostic (1.54e-1)" "unprognostic (1.12e-1)" "unprognostic (1.31e-2)" "unprognostic (1.10e-1)" ICA1 "ICA69, ICAp69" ENSG00000003147 "Islet cell autoantigen 1" Q05084 7 8113184-8262687 "Predicted intracellular proteins, Predicted membrane proteins" "Neurotransmitter transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 521.2;Cardiomyocytes: 352.3;Distal convoluted tubule cells: 582.3;Early spermatids: 863.2;Late spermatids: 1438.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "T-reg: 30.0" "Lineage enriched" "Detected in many" 9 "T-cells: 30.0" "Cancer enhanced" "Detected in many" "Neuroblastoma: 88.4" "Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Skeletal muscle - Endothelial cells, Spleen - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017646, HPA061452" Approved Supported Vesicles,Cytosol NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 8: Pancreas - Proteolysis" "Cluster 34: Non-specific - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 8 "Vesicles, Cytosol" "HPA017646: , HPA061452: " "unprognostic (1.10e-2)" "unprognostic (6.00e-2)" "unprognostic (3.16e-1)" "unprognostic (5.88e-2)" "unprognostic (2.73e-2)" "unprognostic (1.62e-1)" "unprognostic (4.82e-2)" "unprognostic (3.60e-2)" "unprognostic (1.06e-1)" "unprognostic (1.13e-1)" "potential prognostic favorable (2.71e-10)" "unprognostic (2.57e-2)" "unprognostic (1.18e-3)" "unprognostic (3.11e-2)" "unprognostic (1.82e-2)" "unprognostic (3.75e-1)" "unprognostic (3.59e-2)" "unprognostic (3.38e-2)" "unprognostic (1.35e-1)" "unprognostic (1.48e-1)" "unprognostic (1.91e-1)" "unprognostic (9.63e-2)" "unprognostic (1.49e-1)" "unprognostic (8.17e-2)" "unprognostic (8.34e-3)" "unprognostic (7.33e-2)" "unprognostic (1.25e-1)" "unprognostic (3.04e-1)" "unprognostic (8.93e-2)" "unprognostic (7.24e-3)" "unprognostic (2.81e-2)" ICA1L "ALS2CR14, ALS2CR15" ENSG00000163596 "Islet cell autoantigen 1 like" Q8NDH6 2 202773150-202871766 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.0" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 268.8;Brain inhibitory neurons: 202.0;Ependymal cells: 256.1;Lactotrophs: 242.4;Other brain neurons: 205.9;Somatotrophs: 310.8;Thyrotrophs: 231.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042507 Approved Approved Mitochondria NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 65: Brain - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" 2 Mitochondria "HPA042507: " "unprognostic (4.24e-3)" "unprognostic (2.06e-3)" "unprognostic (1.99e-1)" "unprognostic (1.29e-1)" "unprognostic (1.86e-1)" "unprognostic (2.94e-1)" "unprognostic (4.26e-1)" "unprognostic (1.95e-1)" "unprognostic (2.75e-2)" "unprognostic (2.75e-1)" "unprognostic (1.30e-1)" "unprognostic (1.07e-2)" "unprognostic (2.45e-1)" "unprognostic (1.55e-3)" "unprognostic (1.17e-1)" "unprognostic (4.41e-2)" "unprognostic (2.74e-2)" "unprognostic (7.89e-2)" "unprognostic (5.40e-2)" "unprognostic (1.64e-3)" "unprognostic (7.20e-3)" "unprognostic (1.61e-1)" "unprognostic (1.06e-1)" "unprognostic (1.59e-2)" "unprognostic (6.44e-3)" "unprognostic (3.47e-1)" "unprognostic (3.04e-1)" "unprognostic (1.37e-1)" "unprognostic (5.60e-2)" ICAM1 "BB2, CD54" ENSG00000090339 "Intercellular adhesion molecule 1" P05362 19 10271093-10286615 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 233.5;urinary bladder: 200.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 906.0;Alveolar cells type 2: 735.5;Kupffer cells: 314.6;Macrophages: 300.0;monocytes: 568.2;Neutrophils: 1484.9;Transitional alveolar cells: 695.7;Vascular endothelial cells: 507.8" "Cell type enriched" "Detected in some" 8 "endothelial cell: 105.4" "Cancer enhanced" "Detected in all" "Lung Adenocarcinoma (TCGA): 244.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Neutrophils, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002126, CAB002142, HPA004877" Enhanced Approved "Vesicles,Plasma membrane,Cytosol" NA NA 240000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 36 "Plasma membrane" "Vesicles, Cytosol" "CAB002142: , HPA002126: , HPA004877: " "unprognostic (8.42e-2)" "unprognostic (4.57e-3)" "unprognostic (7.39e-2)" "unprognostic (2.30e-2)" "unprognostic (3.86e-1)" "unprognostic (1.59e-1)" "unprognostic (1.61e-3)" "unprognostic (4.21e-2)" "unprognostic (1.04e-1)" "unprognostic (4.67e-2)" "potential prognostic unfavorable (2.83e-4)" "unprognostic (2.22e-2)" "unprognostic (2.58e-2)" "unprognostic (1.95e-3)" "unprognostic (3.28e-1)" "unprognostic (6.22e-2)" "unprognostic (1.21e-2)" "unprognostic (2.07e-2)" "unprognostic (2.50e-2)" "unprognostic (4.08e-2)" "unprognostic (2.93e-1)" "unprognostic (2.24e-2)" "unprognostic (1.04e-2)" "unprognostic (8.65e-2)" "unprognostic (1.65e-1)" "potential prognostic favorable (2.21e-4)" "unprognostic (9.78e-2)" "unprognostic (1.21e-1)" "unprognostic (8.87e-3)" "unprognostic (1.17e-1)" "unprognostic (6.59e-2)" ICAM2 CD102 ENSG00000108622 "Intercellular adhesion molecule 2" P13598 17 64002594-64020634 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 156.5" "Cell type enhanced" "Detected in many" "Lymphatic endothelial cells: 101.5;Megakaryocyte progenitors: 57.1;Megakaryocyte-Erythroid progenitors: 64.8;Megakaryocytes: 111.3;NK-cells: 83.6;Plasma cells: 136.1;Platelets: 608.1;Vascular endothelial cells: 198.5" "Cell type enriched" "Detected in some" 4 "endothelial cell: 176.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 72.4;lymphoma: 56.2;Myeloma: 73.0" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Lung - Endothelial cells, Minor Salivary Gland - Endothelial cells, Pituitary gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Testis - Endothelial cells, Thyroid gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA071155, CAB080601" Enhanced Approved "Plasma membrane,Cytosol" NA NA 120000000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 5: Spleen - Immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 33 "Plasma membrane" Cytosol "CAB080601: , HPA071155: " "unprognostic (2.15e-1)" "unprognostic (2.05e-2)" "unprognostic (1.28e-1)" "unprognostic (1.60e-3)" "unprognostic (4.22e-1)" "unprognostic (1.38e-2)" "unprognostic (1.41e-1)" "unprognostic (3.40e-2)" "unprognostic (6.12e-3)" "unprognostic (2.16e-2)" "validated prognostic favorable (2.90e-4)" "validated prognostic favorable (8.15e-4)" "unprognostic (1.68e-1)" "unprognostic (1.37e-1)" "unprognostic (9.67e-2)" "unprognostic (4.29e-2)" "unprognostic (2.41e-1)" "unprognostic (2.93e-2)" "unprognostic (6.33e-2)" "unprognostic (1.48e-1)" "unprognostic (6.32e-2)" "unprognostic (1.55e-2)" "unprognostic (6.11e-3)" "unprognostic (1.35e-2)" "unprognostic (1.90e-1)" "unprognostic (2.79e-2)" "unprognostic (7.51e-3)" "unprognostic (5.65e-2)" "unprognostic (7.73e-3)" "unprognostic (1.70e-1)" "unprognostic (1.11e-2)" ICAM3 "CD50, CDW50, ICAM-R" ENSG00000076662 "Intercellular adhesion molecule 3" P32942 19 10333776-10339661 "CD markers, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Phagocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 167.4;lymphoid tissue: 88.8" "Cell type enhanced" "Detected in many" "B-cells: 91.2;Hematopoietic stem cells: 116.9;Hepatocytes: 197.7;Innate lymphoid cells: 99.0;monocytes: 91.1;Neutrophil progenitors: 223.0;Neutrophils: 596.1;NK-cells: 123.3;Plasma cells: 211.8;T-cells: 120.4" "Cell type enriched" "Detected in some" 14 "leukocyte: 61.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1772.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 1772.8" "Cancer enhanced" "Detected in all" "Leukemia: 103.0;Myeloma: 120.8" "Adipose subcutaneous - T-cells, Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Lung - Neutrophils_2, Minor Salivary Gland - Plasma cells, Pituitary gland - T-cells, Prostate - T-cells, Spleen - Neutrophils_2" "Low region specificity" "Detected in many" "CAB002498, HPA049820" Enhanced Approved "Nucleoplasm,Nuclear membrane,Mitochondria" NA NA 14000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 10 Mitochondria "Nucleoplasm, Nuclear membrane" "CAB002498: , HPA049820: " "unprognostic (1.64e-3)" "unprognostic (3.12e-2)" "unprognostic (1.42e-1)" "unprognostic (3.32e-1)" "unprognostic (5.57e-2)" "unprognostic (1.43e-2)" "unprognostic (2.72e-3)" "unprognostic (3.61e-3)" "potential prognostic favorable (2.35e-4)" "unprognostic (2.82e-3)" "unprognostic (1.71e-2)" "unprognostic (2.16e-2)" "unprognostic (9.28e-2)" "unprognostic (3.97e-2)" "unprognostic (3.61e-1)" "unprognostic (8.03e-3)" "unprognostic (1.64e-1)" "unprognostic (1.51e-1)" "unprognostic (1.45e-1)" "unprognostic (2.21e-3)" "unprognostic (1.20e-1)" "unprognostic (6.67e-2)" "unprognostic (5.37e-2)" "unprognostic (2.59e-1)" "unprognostic (1.84e-3)" "unprognostic (2.32e-2)" "unprognostic (1.27e-2)" "unprognostic (5.67e-2)" "unprognostic (1.51e-1)" "unprognostic (2.15e-1)" "unprognostic (5.94e-2)" ICAM4 "CD242, LW" ENSG00000105371 "Intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)" Q14773 19 10286955-10288522 "Blood group antigen proteins, CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Blood group antigen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 12.6;lung: 8.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 25.6;Alveolar cells type 2: 75.5;Erythrocyte progenitors: 30.6;Megakaryocyte progenitors: 17.8;Megakaryocyte-Erythroid progenitors: 36.7;Megakaryocytes: 30.9;Neutrophils: 33.4;Respiratory basal cells: 17.2;Transitional alveolar cells: 71.4;Vascular endothelial cells: 18.8" "Cell type enhanced" "Detected in single" "leukocyte: 1.8" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 16.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "non-classical monocyte: 216.1" "Lineage enriched" "Detected in many" 7 "monocytes: 216.1" "Cancer enriched" "Detected in many" 5 "Leukemia: 35.5" "Low region specificity" "Detected in some" "Not detected" "Not detected" "Intracellular and membrane" "Cell adhesion" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 15: Bone marrow - Innate immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "unprognostic (1.12e-1)" "unprognostic (1.69e-1)" "unprognostic (1.33e-2)" "unprognostic (2.16e-2)" "unprognostic (2.24e-3)" "unprognostic (3.98e-2)" "potential prognostic unfavorable (2.09e-5)" "unprognostic (3.11e-1)" "potential prognostic unfavorable (2.96e-4)" "unprognostic (8.13e-2)" "unprognostic (1.62e-3)" "unprognostic (1.85e-1)" "unprognostic (3.46e-1)" "unprognostic (7.91e-2)" "unprognostic (1.55e-1)" "unprognostic (1.54e-1)" "unprognostic (7.85e-2)" "unprognostic (9.83e-3)" "unprognostic (2.26e-2)" "unprognostic (3.74e-2)" "unprognostic (9.85e-2)" "unprognostic (2.03e-2)" "unprognostic (1.60e-1)" ICAM5 "TLCN, TLN" ENSG00000105376 "Intercellular adhesion molecule 5" Q9UMF0 19 10289952-10296778 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 22.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 27.7;Alveolar cells type 2: 32.7;Brain excitatory neurons: 28.5;Brain inhibitory neurons: 21.0;Breast myoepithelial cells: 12.9;Mesothelial cells: 15.5;Respiratory ciliated cells: 12.5;Transitional alveolar cells: 28.6" "Cell type enhanced" "Detected in many" "hippocampal dentate gyrus: 75.3" "Cancer enhanced" "Detected in some" "Thyroid Carcinoma (TCGA): 3.0" "Group enriched" "Detected in many" 5 "amygdala: 74.9;basal ganglia: 78.1;cerebral cortex: 97.2;hippocampal formation: 142.6;white matter: 37.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 24.0" "Testis - Spermatocytes" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 15 "amygdala: 54.3;basal ganglia: 59.8;cerebral cortex: 67.0;hippocampal formation: 100.2;olfactory bulb: 36.8" "HPA008943, HPA009083, CAB025178" Enhanced NA NA 160000 "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 35: Neurons - Synaptic function & neurogenesis" 42 "CAB025178: , HPA008943: , HPA009083: " "unprognostic (3.45e-1)" "unprognostic (4.44e-2)" "unprognostic (4.10e-1)" "unprognostic (6.77e-3)" "unprognostic (2.49e-2)" "unprognostic (5.32e-2)" "unprognostic (4.26e-3)" "potential prognostic unfavorable (6.33e-4)" "unprognostic (6.25e-2)" ICE1 KIAA0947 ENSG00000164151 "Interactor of little elongation complex ELL subunit 1" Q9Y2F5 5 5420664-5490220 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054452, HPA061934" Uncertain Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 29: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 11 "Nucleoplasm, Nuclear bodies" "HPA054452: , HPA061934: " "unprognostic (2.27e-2)" "unprognostic (2.40e-2)" "unprognostic (1.74e-2)" "unprognostic (3.05e-1)" "unprognostic (8.57e-2)" "unprognostic (2.47e-2)" "unprognostic (5.63e-2)" "unprognostic (5.06e-2)" "unprognostic (3.22e-2)" "potential prognostic favorable (1.14e-4)" "unprognostic (2.02e-2)" "unprognostic (5.30e-2)" "potential prognostic unfavorable (1.25e-5)" "unprognostic (8.03e-2)" "unprognostic (2.75e-2)" "unprognostic (7.66e-2)" "unprognostic (1.37e-1)" "unprognostic (2.02e-1)" "unprognostic (1.79e-1)" "unprognostic (1.42e-1)" "potential prognostic unfavorable (3.74e-4)" "unprognostic (3.30e-2)" "potential prognostic favorable (8.64e-4)" "unprognostic (2.25e-1)" "unprognostic (2.74e-1)" "unprognostic (1.80e-1)" "unprognostic (2.79e-1)" "unprognostic (3.99e-3)" "unprognostic (1.63e-1)" ICE2 "BRCC1, FLJ11896, NARG2" ENSG00000128915 "Interactor of little elongation complex ELL subunit 2" Q659A1 15 60419609-60479160 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 32.5" "Cell type enhanced" "Detected in all" "Myonuclei: 266.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040058 Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 58: Non-specific - Nuclear processes" "Cluster 55: Myocytes - Oxidative muscle function" 15 "Nucleoplasm, Nuclear bodies" Cytosol "HPA040058: " "unprognostic (4.06e-2)" "unprognostic (9.01e-2)" "unprognostic (9.67e-2)" "unprognostic (1.94e-1)" "unprognostic (8.49e-3)" "unprognostic (8.18e-2)" "unprognostic (6.16e-2)" "unprognostic (2.16e-1)" "unprognostic (2.07e-2)" "potential prognostic favorable (8.01e-8)" "unprognostic (5.67e-3)" "unprognostic (1.45e-1)" "unprognostic (1.12e-2)" "unprognostic (3.14e-2)" "unprognostic (1.04e-1)" "unprognostic (2.90e-1)" "unprognostic (1.44e-1)" "unprognostic (1.31e-1)" "unprognostic (4.80e-1)" "unprognostic (2.25e-1)" "unprognostic (3.10e-2)" "unprognostic (5.14e-3)" "unprognostic (3.95e-3)" "unprognostic (7.21e-2)" "unprognostic (1.36e-1)" "unprognostic (1.81e-1)" "unprognostic (4.11e-1)" "unprognostic (6.86e-2)" "unprognostic (7.33e-2)" ICMT "HSTE14, PCCMT, PPMT" ENSG00000116237 "Isoprenylcysteine carboxyl methyltransferase" O60725 1 6221193-6235972 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 98.3;Esophageal apical cells: 99.6;Extravillous trophoblasts: 104.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Fibroblasts_1, Thyroid gland - Thyroid glandular cells" "Region enriched" "Detected in all" 5 "cerebellum: 112.8" "Low region specificity" "Detected in all" "HPA032024, HPA032025" Uncertain NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 54: Immune cells - T cell receptor" "Cluster 37: Non-specific - mRNA processing" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 13 "HPA032024: , HPA032025: " "unprognostic (6.44e-3)" "potential prognostic unfavorable (6.16e-4)" "unprognostic (1.28e-1)" "unprognostic (4.27e-3)" "unprognostic (1.21e-2)" "unprognostic (1.53e-2)" "unprognostic (1.10e-1)" "unprognostic (9.51e-2)" "unprognostic (1.45e-1)" "unprognostic (6.98e-3)" "potential prognostic favorable (9.28e-5)" "unprognostic (1.90e-2)" "unprognostic (9.00e-3)" "validated prognostic unfavorable (9.01e-5)" "validated prognostic unfavorable (1.36e-5)" "unprognostic (4.27e-2)" "unprognostic (2.32e-2)" "unprognostic (1.96e-2)" "unprognostic (2.03e-1)" "unprognostic (1.99e-1)" "unprognostic (1.98e-1)" "unprognostic (2.10e-1)" "unprognostic (1.98e-2)" "unprognostic (1.24e-1)" "unprognostic (2.57e-3)" "unprognostic (6.32e-2)" "unprognostic (5.54e-2)" "unprognostic (5.21e-2)" "unprognostic (1.36e-1)" "unprognostic (1.27e-1)" "unprognostic (5.03e-2)" ICOS "AILIM, CD278" ENSG00000163600 "Inducible T cell costimulator" Q9Y6W8 2 203936763-203961577 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "bone marrow: 15.6;lymphoid tissue: 18.8" "Group enriched" "Detected in some" 7 "Innate lymphoid cells: 148.1;T-cells: 299.8" "Cell type enriched" "Detected in single" 136 "leukocyte: 86.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 29.2" "Lineage enriched" "Detected in single" 54 "T-cells: 29.2" "Cancer enhanced" "Detected in some" "Leukemia: 2.4;lymphoma: 2.6" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Minor Salivary Gland - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Skin - T-cells, Testis - Spermatogonia, Thyroid gland - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB032575, HPA034865" Approved Approved "Plasma membrane,Actin filaments" "Intracellular and membrane" "No annotated function" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" 5 "Plasma membrane" "Actin filaments" "CAB032575: , HPA034865: " "unprognostic (3.34e-2)" "unprognostic (7.43e-2)" "potential prognostic favorable (4.60e-4)" "unprognostic (6.97e-2)" "potential prognostic favorable (6.45e-4)" "unprognostic (1.47e-1)" "unprognostic (1.23e-1)" "unprognostic (3.87e-2)" "unprognostic (4.90e-3)" "unprognostic (5.07e-1)" "unprognostic (1.88e-1)" "unprognostic (1.72e-1)" "unprognostic (1.37e-2)" "unprognostic (6.94e-3)" "unprognostic (4.13e-2)" "unprognostic (5.09e-2)" ICOSLG "B7-H2, B7h, B7H2, B7RP-1, B7RP1, CD275, GL50, ICOS-L, ICOSL, KIAA0653" ENSG00000160223 "Inducible T cell costimulator ligand" O75144 21 44215382-44241446 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, B-cell activation, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "B-cells: 2.6;cDC: 2.1;Endometrial glandular cells: 1.8;Esophageal apical cells: 2.5;Foveolar cells: 2.7;pDCs: 3.2;Podocytes: 3.1;Renal connecting tubule cells: 2.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026037, HPA029179, CAB079997" Approved Approved "Vesicles,Plasma membrane" NA NA 32000000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 6: Leukemia - Signal transduction" "Cluster 82: Dendritic cells - Antigen presentation" 3 "Vesicles, Plasma membrane" "CAB026037: , CAB079997: , HPA029179: " "unprognostic (2.07e-1)" "potential prognostic unfavorable (6.31e-4)" "unprognostic (2.83e-3)" "unprognostic (7.04e-3)" "unprognostic (3.61e-2)" "unprognostic (4.54e-2)" "unprognostic (1.20e-2)" "unprognostic (3.54e-2)" "unprognostic (2.70e-1)" "unprognostic (1.21e-1)" "unprognostic (8.81e-2)" "unprognostic (7.04e-3)" "unprognostic (6.07e-2)" "unprognostic (1.83e-1)" "unprognostic (1.46e-2)" "unprognostic (1.61e-2)" "unprognostic (7.53e-2)" "unprognostic (3.97e-1)" "unprognostic (2.86e-1)" "unprognostic (3.03e-2)" "potential prognostic unfavorable (3.63e-4)" "unprognostic (1.26e-2)" "unprognostic (2.65e-3)" "unprognostic (1.24e-1)" "unprognostic (2.28e-1)" "unprognostic (2.44e-2)" "unprognostic (1.47e-1)" "unprognostic (6.24e-2)" "unprognostic (1.36e-1)" "unprognostic (2.87e-1)" "unprognostic (1.70e-1)" ID1 "bHLHb24, dJ857M17.1.2" ENSG00000125968 "Inhibitor of DNA binding 1" P41134 20 31605283-31606515 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Developmental protein, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial luminal cells: 1049.4;Esophageal apical cells: 3645.3;Esophageal basal cells: 1134.7;Esophageal suprabasal cells: 2030.4;Prostatic club cells: 1685.4;Prostatic hillock cells: 1926.8;Urothelial cells: 866.2;Vascular endothelial cells: 873.5" "Cell type enriched" "Detected in many" 5 "endothelial cell: 608.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "neutrophil: 1.1" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.1" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025915, HPA027874, HPA058518, HPA068861" Approved Enhanced Nucleoplasm NA No "Cluster 21: Neutrophils - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 33 Nucleoplasm "CAB025915: , HPA027874: , HPA058518: , HPA068861: " "unprognostic (4.94e-2)" "unprognostic (1.46e-1)" "potential prognostic favorable (4.74e-4)" "unprognostic (1.56e-2)" "unprognostic (9.97e-2)" "unprognostic (2.10e-3)" "unprognostic (2.16e-2)" "potential prognostic favorable (2.32e-4)" "unprognostic (1.10e-1)" "unprognostic (3.08e-2)" "unprognostic (8.42e-3)" "unprognostic (5.26e-3)" "unprognostic (3.33e-1)" "unprognostic (3.33e-1)" "unprognostic (4.85e-2)" "unprognostic (9.89e-3)" "unprognostic (3.71e-2)" "potential prognostic unfavorable (4.90e-4)" "unprognostic (1.52e-1)" "unprognostic (1.63e-1)" "unprognostic (1.28e-1)" "unprognostic (1.93e-2)" "unprognostic (1.24e-2)" "unprognostic (1.97e-1)" "unprognostic (2.23e-2)" "unprognostic (1.67e-1)" "unprognostic (1.00e-1)" "unprognostic (2.35e-2)" "unprognostic (1.68e-1)" "unprognostic (1.31e-3)" "unprognostic (1.95e-2)" ID2 "bHLHb26, GIG8" ENSG00000115738 "Inhibitor of DNA binding 2" Q02363 2 8678845-8684461 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Developmental protein, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 790.2;parathyroid gland: 1136.9" "Cell type enhanced" "Detected in many" "cDC: 1027.0;Colonocytes: 750.3;Endometrial luminal cells: 853.7;Goblet cells: 803.5;Innate lymphoid cells: 877.6;Mast cells: 839.8;Syncytiotrophoblasts: 760.6" "Cell type enhanced" "Detected in many" "astrocyte: 370.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 1041.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027612 Approved "Nucleoplasm,Nuclear bodies,Centrosome" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 53: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 82: Dendritic cells - Antigen presentation" 47 "Nucleoplasm, Nuclear bodies" Centrosome "HPA027612: " "unprognostic (5.48e-2)" "unprognostic (4.92e-1)" "unprognostic (2.37e-2)" "unprognostic (6.66e-3)" "unprognostic (1.58e-1)" "unprognostic (3.27e-1)" "unprognostic (8.58e-2)" "unprognostic (2.48e-1)" "unprognostic (1.60e-2)" "unprognostic (3.36e-1)" "potential prognostic favorable (5.95e-8)" "unprognostic (8.92e-3)" "unprognostic (3.62e-2)" "unprognostic (8.81e-2)" "unprognostic (1.55e-2)" "unprognostic (2.31e-3)" "potential prognostic favorable (8.88e-4)" "unprognostic (2.01e-1)" "unprognostic (2.62e-1)" "unprognostic (2.30e-1)" "unprognostic (7.46e-2)" "unprognostic (2.09e-1)" "unprognostic (6.19e-2)" "unprognostic (3.59e-1)" "unprognostic (8.65e-3)" "unprognostic (1.43e-1)" "unprognostic (4.55e-1)" "unprognostic (9.78e-2)" "unprognostic (1.89e-1)" "unprognostic (1.08e-3)" "unprognostic (1.49e-2)" ID3 "bHLHb25, HEIR-1" ENSG00000117318 "Inhibitor of DNA binding 3" Q02535 1 23557926-23559501 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Myogenesis, Transcription, Transcription regulation" Repressor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 460.8" "Cell type enhanced" "Detected in many" "Astrocytes: 122.8;Endometrial ciliated cells: 34.3;Endometrial glandular cells: 27.2;Endometrial luminal cells: 48.9;Endometrial secretory cells: 40.5;Ependymal cells: 30.8;Hepatic stellate cells: 38.7;Papillary tip epithelial cells: 22.4;Vascular endothelial cells: 40.9;Vascular smooth muscle cells: 34.8" "Cell type enhanced" "Detected in many" "astrocyte: 227.3;endothelial cell: 562.7;vascular associated smooth muscle cell: 393.4" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 285.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 320.1;naive B-cell: 307.8" "Group enriched" "Detected in many" 39 "B-cells: 320.1;T-cells: 177.5" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB021353, HPA024677" Approved Supported Nucleoplasm NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 74: Non-specific - Signal transduction" "Cluster 39: Astrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 104: Brain endothelial cells - Blood brain barrier" 24 Nucleoplasm "CAB021353: , HPA024677: " "unprognostic (1.88e-1)" "unprognostic (7.47e-2)" "unprognostic (2.62e-1)" "unprognostic (8.84e-2)" "unprognostic (7.74e-2)" "unprognostic (1.46e-1)" "unprognostic (6.16e-2)" "potential prognostic favorable (4.19e-4)" "unprognostic (1.64e-1)" "unprognostic (6.04e-2)" "unprognostic (3.92e-2)" "unprognostic (2.95e-3)" "unprognostic (1.76e-1)" "unprognostic (6.79e-2)" "unprognostic (1.27e-1)" "unprognostic (4.40e-2)" "unprognostic (2.83e-1)" "unprognostic (1.22e-1)" "unprognostic (9.49e-2)" "unprognostic (1.33e-2)" "unprognostic (2.90e-2)" "unprognostic (3.65e-1)" "unprognostic (1.21e-1)" "unprognostic (3.66e-1)" "unprognostic (1.29e-1)" "unprognostic (8.16e-2)" "unprognostic (1.91e-1)" "unprognostic (4.68e-1)" "unprognostic (1.94e-1)" "unprognostic (4.68e-3)" "potential prognostic favorable (4.32e-4)" ID4 bHLHb27 ENSG00000172201 "Inhibitor of DNA binding 4" P47928 6 19837370-19842197 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 257.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 347.3;Astrocytes: 315.8;Breast myoepithelial cells: 459.0;Breast secretory cells: 501.4;Endometrial ciliated cells: 426.7;Endometrial glandular cells: 403.3;Endometrial luminal cells: 327.0;Endometrial stromal cells: 347.0;Epididymal basal cells: 334.6;Fallopian secretory cells: 628.7;Müller glia: 415.4;Pericytes: 388.5;Smooth muscle cells: 467.8;Vascular smooth muscle cells: 364.3" "Group enriched" "Detected in many" 5 "astrocyte: 323.8;Bergmann glia: 315.6;ependymal cell: 321.9" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 117.3;Thyroid Carcinoma (TCGA): 134.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Pituitary gland - Undifferentiated cells (Pituitary gland), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075639 Supported Nucleoplasm NA NA "Cluster 33: Thyroid gland - Tissue development" "Cluster 46: Brainstem - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 103: Non-specific - Basic cellular processes" 5 Nucleoplasm "HPA075639: " "unprognostic (2.22e-2)" "unprognostic (1.99e-3)" "unprognostic (1.47e-1)" "unprognostic (1.26e-1)" "unprognostic (2.34e-2)" "unprognostic (5.43e-2)" "unprognostic (2.24e-2)" "unprognostic (6.76e-3)" "unprognostic (9.85e-2)" "unprognostic (2.77e-1)" "validated prognostic favorable (3.10e-5)" "validated prognostic favorable (1.13e-5)" "potential prognostic favorable (1.69e-4)" "unprognostic (5.26e-2)" "unprognostic (1.01e-1)" "unprognostic (1.79e-1)" "unprognostic (2.78e-2)" "unprognostic (2.34e-1)" "unprognostic (2.15e-1)" "unprognostic (2.68e-2)" "unprognostic (1.58e-1)" "potential prognostic favorable (1.77e-4)" "unprognostic (9.09e-2)" "unprognostic (1.75e-2)" "unprognostic (1.16e-1)" "unprognostic (1.51e-1)" "unprognostic (2.83e-1)" "unprognostic (4.82e-2)" "unprognostic (9.56e-3)" "unprognostic (3.50e-3)" "unprognostic (3.54e-2)" IDE ENSG00000119912 "Insulin degrading enzyme" P14735 10 92451684-92574096 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction" "Allosteric enzyme, Host cell receptor for virus entry, Hydrolase, Metalloprotease, Protease, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skin - Keratinocyte (granular), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063478 Approved "Secreted in other tissues" Receptor NA NA 330000 "Cluster 33: Non-specific - ATP binding" "Cluster 47: Testis - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 52: Non-specific - Mitochondria" "Cluster 7: Non-specific - Transcription" 24 "HPA063478: " "unprognostic (1.35e-1)" "unprognostic (2.25e-3)" "unprognostic (2.34e-1)" "unprognostic (4.72e-2)" "unprognostic (3.87e-2)" "unprognostic (1.36e-1)" "unprognostic (3.09e-1)" "unprognostic (1.48e-2)" "unprognostic (3.70e-1)" "unprognostic (1.22e-1)" "unprognostic (5.15e-3)" "unprognostic (1.97e-1)" "unprognostic (1.04e-1)" "unprognostic (3.14e-2)" "unprognostic (6.45e-2)" "unprognostic (1.98e-1)" "unprognostic (2.37e-1)" "unprognostic (5.49e-3)" "unprognostic (1.32e-1)" "unprognostic (1.83e-1)" "unprognostic (1.19e-3)" "unprognostic (3.22e-2)" "unprognostic (3.26e-1)" "unprognostic (1.03e-1)" "unprognostic (2.51e-1)" "unprognostic (1.69e-2)" "unprognostic (8.05e-2)" "unprognostic (2.14e-1)" "unprognostic (3.91e-1)" "unprognostic (8.85e-2)" "unprognostic (2.56e-2)" IDH1 ENSG00000138413 "Isocitrate dehydrogenase (NADP(+)) 1" O75874 2 208236229-208266074 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glyoxylate bypass, Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 501.4" "Cell type enhanced" "Detected in all" "Adrenal cortex cells: 343.6;Cytotrophoblasts: 401.9;Hepatocytes: 374.0;Hofbauer cells: 251.4;Urothelial cells: 284.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Macrophages, Pancreas - Macrophages, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033218, HPA035248, HPA057936, CAB062556" Enhanced Approved "Nuclear bodies,Cytosol" NA NA 21000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 7: Liver cancer - Metabolism" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 19 "Nuclear bodies, Cytosol" "CAB033218: , CAB062556: , HPA035248: , HPA057936: " "potential prognostic favorable (3.03e-4)" "unprognostic (4.85e-2)" "unprognostic (3.55e-2)" "unprognostic (5.77e-2)" "unprognostic (1.06e-2)" "unprognostic (3.15e-3)" "unprognostic (2.31e-2)" "unprognostic (7.38e-2)" "unprognostic (8.56e-3)" "potential prognostic unfavorable (5.77e-6)" "unprognostic (7.13e-3)" "unprognostic (7.78e-3)" "unprognostic (5.31e-2)" "unprognostic (1.54e-3)" "unprognostic (4.10e-2)" "unprognostic (5.47e-2)" "unprognostic (4.10e-1)" "unprognostic (2.20e-1)" "unprognostic (5.93e-2)" "unprognostic (2.81e-2)" "unprognostic (3.10e-1)" "unprognostic (1.42e-2)" "unprognostic (8.63e-2)" "unprognostic (4.23e-2)" "unprognostic (1.01e-1)" "unprognostic (2.09e-2)" "unprognostic (4.89e-3)" "unprognostic (1.90e-1)" "unprognostic (2.89e-1)" "unprognostic (3.50e-2)" "unprognostic (6.75e-3)" IDH2 IDH-2 ENSG00000182054 "Isocitrate dehydrogenase (NADP(+)) 2" P48735 15 90083045-90102477 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glyoxylate bypass, Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "heart muscle: 462.3;skeletal muscle: 1220.1;tongue: 1504.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 988.6;Esophageal apical cells: 430.1;Extravillous trophoblasts: 854.9;Migrating cytotrophoblasts: 573.0;Paneth cells: 437.0;Parietal cells: 1126.2;Syncytiotrophoblasts: 766.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Colon - Smooth muscle cells, Heart muscle - Cardiomyocytes, Lung - Mitotic cells (Lung), Skeletal muscle - Skeletal myocytes, Spleen - Mitotic cells (Spleen), Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007831 Enhanced Supported Mitochondria NA NA 4100000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 39: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 24 Mitochondria "HPA007831: " "unprognostic (1.46e-2)" "unprognostic (6.79e-2)" "unprognostic (1.09e-1)" "unprognostic (1.31e-1)" "potential prognostic favorable (3.83e-4)" "unprognostic (1.09e-1)" "unprognostic (1.66e-1)" "unprognostic (2.87e-1)" "unprognostic (2.30e-1)" "unprognostic (1.84e-2)" "potential prognostic favorable (2.20e-5)" "unprognostic (3.67e-2)" "unprognostic (1.78e-2)" "unprognostic (1.08e-1)" "unprognostic (2.46e-1)" "unprognostic (1.30e-1)" "unprognostic (1.04e-1)" "unprognostic (9.76e-3)" "unprognostic (9.43e-2)" "unprognostic (3.64e-1)" "unprognostic (1.40e-1)" "unprognostic (2.19e-2)" "unprognostic (2.54e-2)" "unprognostic (1.71e-1)" "unprognostic (3.75e-2)" "unprognostic (2.40e-1)" "unprognostic (5.74e-2)" "unprognostic (5.02e-3)" "unprognostic (1.15e-1)" "unprognostic (4.84e-2)" "unprognostic (1.01e-1)" IDH3A ENSG00000166411 "Isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha" P50213 15 78131498-78171945 "Citric acid cycle related proteins, Disease related genes, Enzymes, Essential proteins, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" Oxidoreductase "Disease variant, FDA approved drug targets, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 92.7" "Cell type enhanced" "Detected in many" "pDCs: 205.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 144.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041465, HPA062971" Supported Enhanced Mitochondria No No 16000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 52: Non-specific - Cellular respiration" "Cluster 23: Choroid plexus - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 10 Mitochondria "HPA041465: , HPA062971: " "unprognostic (8.71e-2)" "unprognostic (4.76e-2)" "unprognostic (1.30e-1)" "unprognostic (2.41e-2)" "unprognostic (1.77e-2)" "unprognostic (1.10e-1)" "unprognostic (2.71e-2)" "unprognostic (1.04e-1)" "unprognostic (3.52e-1)" "potential prognostic unfavorable (6.15e-4)" "validated prognostic favorable (9.24e-5)" "validated prognostic favorable (4.52e-4)" "unprognostic (1.03e-2)" "unprognostic (3.04e-1)" "unprognostic (1.05e-3)" "unprognostic (1.59e-1)" "unprognostic (1.19e-1)" "unprognostic (6.56e-2)" "unprognostic (8.43e-2)" "unprognostic (3.59e-1)" "unprognostic (3.83e-1)" "unprognostic (1.51e-2)" "unprognostic (1.05e-1)" "unprognostic (2.41e-2)" "unprognostic (3.46e-3)" "unprognostic (1.22e-1)" "unprognostic (4.29e-2)" "unprognostic (9.01e-2)" "unprognostic (2.97e-1)" "unprognostic (5.64e-2)" "unprognostic (1.14e-1)" IDH3B RP46 ENSG00000101365 "Isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta" O43837 20 2658395-2664219 "Citric acid cycle related proteins, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 168.4;Late spermatids: 169.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Minor Salivary Gland - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049387, HPA054180" Supported Enhanced Mitochondria NA NA 4200 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 97: Non-specific - Cellular respiration" 5 Mitochondria "HPA049387: , HPA054180: " "unprognostic (2.25e-1)" "unprognostic (1.85e-2)" "unprognostic (2.84e-1)" "unprognostic (8.35e-2)" "unprognostic (3.01e-1)" "unprognostic (2.16e-1)" "unprognostic (3.10e-2)" "unprognostic (7.97e-3)" "unprognostic (2.48e-1)" "unprognostic (1.03e-1)" "potential prognostic favorable (8.02e-8)" "unprognostic (1.97e-2)" "potential prognostic favorable (3.55e-4)" "validated prognostic unfavorable (1.04e-5)" "validated prognostic unfavorable (2.34e-4)" "unprognostic (6.60e-2)" "unprognostic (2.57e-1)" "unprognostic (4.72e-2)" "unprognostic (2.30e-1)" "unprognostic (2.33e-1)" "unprognostic (1.44e-1)" "unprognostic (1.09e-1)" "unprognostic (1.66e-1)" "unprognostic (2.87e-1)" "unprognostic (2.00e-1)" "unprognostic (1.24e-1)" "unprognostic (1.02e-1)" "unprognostic (3.16e-1)" "unprognostic (1.42e-1)" "unprognostic (5.00e-2)" "unprognostic (2.23e-1)" IDH3G ENSG00000067829 "Isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma" P51553 X 153785766-153794512 "Citric acid cycle related proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 443.8;Oocytes: 211.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000425, HPA002017" Supported Approved "Nucleoli,Plasma membrane,Mitochondria" Yes No 9400 "Cluster 42: Non-specific - Vesicular transport" "Cluster 52: Non-specific - Cellular respiration" "Cluster 14: Neurons - Synaptic function" "Cluster 36: Non-specific - mRNA processing" "Cluster 97: Non-specific - Cellular respiration" 10 "Nucleoli, Mitochondria" "Plasma membrane" "HPA000425: , HPA002017: " "unprognostic (2.31e-2)" "unprognostic (8.48e-3)" "unprognostic (2.95e-1)" "unprognostic (6.94e-2)" "unprognostic (1.03e-1)" "unprognostic (7.87e-3)" "unprognostic (1.89e-1)" "unprognostic (6.63e-3)" "unprognostic (2.08e-2)" "unprognostic (2.22e-3)" "unprognostic (4.52e-3)" "unprognostic (2.61e-1)" "potential prognostic favorable (1.31e-6)" "unprognostic (1.26e-2)" "unprognostic (5.57e-2)" "unprognostic (2.62e-1)" "unprognostic (1.27e-2)" "unprognostic (1.55e-1)" "unprognostic (7.42e-2)" "unprognostic (1.25e-1)" "unprognostic (1.25e-3)" "unprognostic (1.20e-2)" "unprognostic (1.70e-1)" "unprognostic (4.62e-1)" "unprognostic (3.95e-1)" "unprognostic (1.76e-1)" "unprognostic (3.46e-2)" "unprognostic (2.31e-1)" "unprognostic (3.16e-1)" "unprognostic (1.50e-1)" "unprognostic (9.51e-2)" IDI1 ENSG00000067064 "Isopentenyl-diphosphate delta isomerase 1" Q13907 10 1039152-1049119 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Isoprene biosynthesis, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Breast lactating cells: 795.5;Epididymal principal cells: 1187.8;Esophageal apical cells: 750.9;Neutrophils: 458.0;Urothelial cells: 580.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Lung - Alveolar cells type 2, Pituitary gland - Corticotropes, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039169 Approved NA NA 52000 "Cluster 35: Neutrophils - Protein binding" "Cluster 76: Non-specific - Metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 2 "HPA039169: " "unprognostic (1.20e-2)" "unprognostic (1.90e-2)" "unprognostic (3.50e-2)" "unprognostic (3.91e-2)" "unprognostic (2.59e-1)" "unprognostic (4.90e-2)" "unprognostic (1.08e-1)" "potential prognostic favorable (9.61e-4)" "unprognostic (1.53e-1)" "unprognostic (3.90e-2)" "potential prognostic favorable (5.97e-7)" "unprognostic (8.31e-3)" "unprognostic (3.10e-1)" "unprognostic (2.66e-2)" "unprognostic (1.64e-2)" "unprognostic (9.84e-2)" "unprognostic (8.33e-3)" "unprognostic (1.61e-1)" "unprognostic (1.05e-1)" "unprognostic (1.30e-1)" "unprognostic (6.21e-2)" "unprognostic (1.71e-1)" "unprognostic (8.70e-3)" "unprognostic (3.98e-1)" "unprognostic (1.02e-1)" "unprognostic (8.84e-2)" "unprognostic (1.69e-3)" "unprognostic (9.76e-2)" "unprognostic (1.78e-1)" "potential prognostic unfavorable (7.37e-5)" "unprognostic (7.93e-2)" IDI2 IPPI2 ENSG00000148377 "Isopentenyl-diphosphate delta isomerase 2" Q9BXS1 10 1018910-1025859 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Isoprene biosynthesis, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 24 "skeletal muscle: 261.6" "Group enriched" "Detected in some" 8 "Cardiomyocytes: 148.6;Myonuclei: 136.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Prostate Adenocarcinoma (TCGA): 4.6;Uterine Corpus Endometrial Carcinoma (TCGA): 5.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "skin cancer: 1.0" "Not detected" "Not detected" HPA041254 Supported Vesicles NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 37: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 55: Myocytes - Oxidative muscle function" 1 Vesicles "HPA041254: " "unprognostic (1.71e-1)" "potential prognostic unfavorable (5.61e-4)" "unprognostic (6.73e-2)" "unprognostic (2.40e-1)" "unprognostic (4.32e-2)" IDNK "bA522I20.2, C9orf103, hGntK" ENSG00000148057 "IDNK gluconokinase" Q5T6J7 9 83623049-83644130 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 54.7;liver: 65.8" "Cell type enhanced" "Detected in many" "Enterocytes: 98.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020378, HPA058429" Approved Approved Mitochondria,Cytosol NA NA "Cluster 32: Basophils - Transcription" "Cluster 76: Non-specific - Metabolism" "Cluster 54: Immune cells - T cell receptor" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 1: Enterocytes - Absorption and Digestion" "Mitochondria, Cytosol" "HPA020378: , HPA058429: " "unprognostic (2.73e-2)" "unprognostic (2.83e-3)" "unprognostic (1.52e-1)" "unprognostic (1.13e-1)" "unprognostic (5.74e-2)" "unprognostic (1.30e-1)" "unprognostic (2.34e-1)" "unprognostic (2.96e-1)" "unprognostic (2.78e-1)" "validated prognostic favorable (2.22e-7)" "validated prognostic favorable (6.60e-4)" "unprognostic (4.98e-2)" "unprognostic (1.82e-2)" "unprognostic (1.52e-1)" "unprognostic (3.63e-3)" "unprognostic (6.71e-2)" "unprognostic (1.55e-1)" "unprognostic (2.95e-1)" "unprognostic (1.20e-1)" "unprognostic (1.97e-2)" "unprognostic (1.89e-1)" "unprognostic (1.62e-1)" "unprognostic (6.20e-2)" "unprognostic (7.68e-2)" "unprognostic (1.05e-2)" "unprognostic (2.91e-2)" "unprognostic (7.58e-2)" "unprognostic (5.03e-2)" "potential prognostic favorable (5.62e-4)" IDO1 "IDO, INDO" ENSG00000131203 "Indoleamine 2,3-dioxygenase 1" P14902 8 39902275-39928790 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Immunity, Tryptophan catabolism" "Dioxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 55.0;placenta: 104.2" "Cell type enhanced" "Detected in some" "cDC: 109.7;Endometrial ciliated cells: 46.6;Endometrial glandular cells: 365.3;Endometrial luminal cells: 314.5;Endometrial secretory cells: 67.1;Epididymal basal cells: 75.8" "Cell type enhanced" "Detected in some" "leukocyte: 3.0;lower rhombic lip: 1.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 14 "eosinophil: 465.9" "Lineage enriched" "Detected in many" 18 "granulocytes: 465.9" "Cancer enhanced" "Detected in many" "thyroid cancer: 15.4" "Adipose subcutaneous - T-cells, Kidney - T-cells, Skeletal muscle - Skeletal myocytes, Spleen - T-cells" "Region enriched" "Detected in many" 12 "basal ganglia: 34.1" "Low region specificity" "Detected in all" "HPA023072, HPA023149, HPA027772, CAB072820" Enhanced Approved "Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Basal body" Yes NA "Cluster 22: Eosinophils - Transcription" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 23: Choroid plexus - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 51: Secretory epithelial cells - Mixed function" 1 Microtubules "Cytokinetic bridge, Mitotic spindle, Primary cilium, Basal body" "CAB072820: , HPA023072: , HPA023149: , HPA027772: " "unprognostic (6.47e-2)" "unprognostic (3.04e-2)" "unprognostic (2.03e-1)" "unprognostic (8.61e-2)" "unprognostic (1.72e-1)" "unprognostic (8.76e-3)" "unprognostic (1.74e-1)" "unprognostic (2.37e-1)" "unprognostic (4.36e-3)" "unprognostic (1.73e-1)" "unprognostic (2.09e-1)" "unprognostic (1.40e-1)" "potential prognostic unfavorable (1.65e-4)" "unprognostic (2.66e-1)" "unprognostic (1.43e-2)" "unprognostic (3.54e-2)" "unprognostic (1.25e-1)" "unprognostic (1.29e-1)" "unprognostic (2.53e-1)" "unprognostic (9.08e-3)" "unprognostic (2.69e-1)" "unprognostic (4.00e-2)" "unprognostic (3.14e-2)" "unprognostic (2.02e-1)" "unprognostic (6.54e-2)" "unprognostic (2.82e-2)" "unprognostic (2.20e-3)" "unprognostic (9.41e-2)" "unprognostic (5.36e-2)" "unprognostic (6.17e-2)" "unprognostic (4.03e-2)" IDO2 INDOL1 ENSG00000188676 "Indoleamine 2,3-dioxygenase 2" Q6ZQW0 8 39934614-40016392 "Metabolic proteins, Predicted intracellular proteins" "Immunity, Tryptophan catabolism" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 17 "liver: 3.1;placenta: 5.2" "Group enriched" "Detected in some" 4 "Endometrial glandular cells: 245.6;Endometrial luminal cells: 316.5" "Cell type enriched" "Detected in some" 6 "lower rhombic lip: 10.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes, Spleen - T-cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA054911 Approved Cytosol NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 5: Rhabdoid - Unknown function" "Cluster 51: Secretory epithelial cells - Mixed function" Cytosol "HPA054911: " "unprognostic (6.62e-2)" "potential prognostic favorable (1.96e-4)" IDS "ID2S, SIDS" ENSG00000010404 "Iduronate 2-sulfatase" P22304 X 149476988-149521096 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "brain: 432.1" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 222.7;Brain inhibitory neurons: 262.3;Choroid plexus epithelial cells: 68.0;Ependymal cells: 106.8;Microglia: 55.1;Oligodendrocytes: 70.8;Other brain neurons: 217.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078003 Approved "Intracellular and membrane" Enzyme NA NA 6300000 "Cluster 35: Neutrophils - Protein binding" "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 109: Neurons - Neuronal signaling" 61 "HPA078003: " "unprognostic (1.58e-2)" "unprognostic (2.84e-2)" "unprognostic (5.45e-2)" "unprognostic (3.50e-1)" "unprognostic (2.00e-1)" "unprognostic (5.30e-3)" "unprognostic (1.07e-1)" "unprognostic (2.39e-3)" "unprognostic (6.75e-3)" "unprognostic (9.69e-2)" "potential prognostic favorable (3.39e-5)" "unprognostic (6.69e-2)" "unprognostic (8.25e-2)" "unprognostic (1.48e-1)" "unprognostic (2.57e-3)" "unprognostic (1.35e-1)" "unprognostic (1.75e-2)" "unprognostic (4.40e-2)" "potential prognostic unfavorable (6.48e-4)" "unprognostic (4.06e-2)" "unprognostic (3.06e-1)" "unprognostic (3.97e-2)" "unprognostic (1.90e-1)" "unprognostic (1.19e-1)" "unprognostic (1.03e-1)" "unprognostic (3.89e-2)" "unprognostic (1.09e-2)" "unprognostic (1.02e-1)" "unprognostic (3.71e-1)" "unprognostic (1.02e-1)" "unprognostic (1.61e-1)" IDUA "MPS1, MPSI" ENSG00000127415 Alpha-L-iduronidase P35475 4 986997-1004564 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025901, HPA046979, HPA054254" Enhanced Supported Vesicles "Intracellular and membrane" Enzyme NA NA 86000 "Cluster 33: Non-specific - ATP binding" "Cluster 64: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 34 Vesicles "CAB025901: , HPA046979: , HPA054254: " "unprognostic (4.68e-3)" "unprognostic (3.66e-1)" "unprognostic (1.71e-2)" "unprognostic (5.35e-2)" "unprognostic (1.51e-1)" "unprognostic (3.47e-3)" "unprognostic (1.46e-1)" "unprognostic (9.77e-2)" "unprognostic (2.46e-2)" "unprognostic (9.84e-2)" "potential prognostic unfavorable (7.00e-5)" "unprognostic (2.00e-1)" "unprognostic (1.04e-2)" "unprognostic (2.46e-1)" "unprognostic (6.33e-2)" "unprognostic (6.52e-2)" "unprognostic (1.37e-1)" "unprognostic (2.98e-3)" "unprognostic (4.78e-1)" "unprognostic (1.37e-2)" "unprognostic (4.00e-3)" "unprognostic (8.79e-2)" "unprognostic (1.35e-1)" "unprognostic (1.61e-2)" "unprognostic (6.51e-3)" "unprognostic (9.22e-2)" "unprognostic (3.41e-3)" "unprognostic (6.52e-2)" "unprognostic (1.10e-1)" "unprognostic (2.05e-2)" "unprognostic (2.50e-1)" IER2 ETR101 ENSG00000160888 "Immediate early response 2" Q9BTL4 19 13150411-13154911 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 2353.5;Decidual stromal cells: 2087.5;Neutrophils: 2177.2" "Cell type enhanced" "Detected in all" "endothelial cell: 247.9;vascular associated smooth muscle cell: 160.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055387, HPA060574" Enhanced Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 15: Bone marrow - Innate immune response" "Cluster 25: Non-specific - Transcription" "Cluster 23: Non-specific - Transcription" "Cluster 20: Non-specific - Transcription regulation" 13 Nucleoplasm "HPA055387: , HPA060574: " "unprognostic (2.71e-1)" "unprognostic (4.30e-2)" "potential prognostic favorable (2.87e-4)" "unprognostic (3.04e-1)" "unprognostic (1.94e-1)" "unprognostic (1.85e-1)" "unprognostic (2.17e-2)" "unprognostic (4.71e-2)" "unprognostic (2.73e-2)" "unprognostic (2.27e-2)" "unprognostic (2.11e-2)" "unprognostic (1.56e-2)" "unprognostic (5.88e-3)" "unprognostic (2.71e-1)" "unprognostic (5.52e-3)" "unprognostic (2.21e-1)" "unprognostic (2.71e-2)" "unprognostic (1.81e-1)" "unprognostic (1.33e-1)" "unprognostic (6.51e-2)" "unprognostic (8.45e-2)" "unprognostic (1.07e-2)" "unprognostic (1.93e-1)" "unprognostic (4.96e-3)" "unprognostic (1.77e-1)" "potential prognostic favorable (3.46e-4)" "unprognostic (4.94e-2)" "unprognostic (3.40e-1)" "unprognostic (2.92e-1)" "unprognostic (4.42e-1)" "unprognostic (3.57e-1)" IER3 "DIF-2, IEX-1, IEX-1L, PRG1" ENSG00000137331 "Immediate early response 3" P46695 6 30743199-30744548 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 178.4;Endometrial luminal cells: 94.1;Endometrial secretory cells: 127.7;Epididymal basal cells: 101.6;Fallopian secretory cells: 70.2;Microglia: 81.1;Neutrophils: 133.2;Renal collecting duct principal cells: 82.6;Renal connecting tubule cells: 87.7" "Group enriched" "Detected in many" 4 "central nervous system macrophage: 94.8;choroid plexus epithelial cell: 28.8;endothelial cell: 83.7;vascular associated smooth muscle cell: 39.1" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 30.5" "Liver - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043847 Approved NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 16 "HPA043847: " "unprognostic (4.56e-1)" "unprognostic (2.95e-1)" "unprognostic (1.99e-1)" "unprognostic (3.47e-1)" "unprognostic (1.50e-1)" "unprognostic (2.67e-1)" "unprognostic (9.45e-3)" "unprognostic (4.45e-2)" "unprognostic (3.55e-2)" "potential prognostic unfavorable (7.37e-4)" "unprognostic (1.60e-1)" "unprognostic (2.65e-1)" "unprognostic (8.08e-1)" "unprognostic (6.46e-2)" "unprognostic (8.96e-2)" "unprognostic (2.90e-1)" "unprognostic (8.11e-2)" "unprognostic (1.20e-1)" "potential prognostic unfavorable (7.23e-4)" "unprognostic (1.04e-1)" "unprognostic (2.81e-1)" "unprognostic (1.78e-1)" "unprognostic (2.99e-1)" "unprognostic (1.21e-1)" "unprognostic (6.09e-1)" "unprognostic (3.82e-1)" "unprognostic (8.10e-1)" "unprognostic (3.37e-1)" "unprognostic (1.44e-1)" IER3IP1 ENSG00000134049 "Immediate early response 3 interacting protein 1" Q9Y5U9 18 47152834-47176364 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Diabetes mellitus, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 22.5;Early primary spermatocytes: 40.8;Enteric transient amplifying cells: 24.0;Enterocytes: 36.4;Epididymal principal cells: 22.3;Gastric chief cells: 49.1;Goblet cells: 22.2;Hepatocytes: 37.4;Parietal cells: 38.9" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" HPA010027 Supported Supported "Endoplasmic reticulum" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 76: Non-specific - Metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 13: Non-specific - Mixed function" "Cluster 67: Plasma cells - Plasma cell differentiation" 36 "Endoplasmic reticulum" "HPA010027: " "unprognostic (2.95e-1)" "unprognostic (1.54e-3)" "unprognostic (1.61e-2)" "unprognostic (7.94e-2)" "unprognostic (5.02e-2)" "unprognostic (2.08e-1)" "unprognostic (1.91e-2)" "unprognostic (9.91e-2)" "unprognostic (1.39e-1)" "unprognostic (1.64e-1)" "potential prognostic favorable (4.67e-5)" "unprognostic (8.20e-3)" "unprognostic (5.20e-2)" "validated prognostic unfavorable (7.86e-4)" "validated prognostic unfavorable (2.19e-5)" "unprognostic (9.92e-2)" "unprognostic (7.05e-2)" "unprognostic (1.01e-1)" "unprognostic (7.29e-2)" "unprognostic (3.17e-3)" "unprognostic (1.76e-2)" "unprognostic (3.35e-1)" "unprognostic (8.52e-2)" "unprognostic (1.66e-2)" "unprognostic (6.67e-2)" "unprognostic (4.23e-2)" "unprognostic (5.94e-2)" "unprognostic (1.45e-1)" "unprognostic (8.03e-2)" "unprognostic (1.36e-1)" "unprognostic (1.28e-1)" IER5 ENSG00000162783 "Immediate early response 5" Q5VY09 1 181088700-181092900 "Predicted intracellular proteins" "Stress response, Transcription, Transcription regulation" "Activator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 284.7;Breast secretory cells: 204.8;cDC: 282.7;Epididymal basal cells: 214.4;Kupffer cells: 264.4;Macrophages: 236.8;monocytes: 253.8" "Cell type enhanced" "Detected in all" "leukocyte: 35.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029894 Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 31: Non-specific - Transcription" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 75: Non-specific - Chaperones and protein folding" 9 Nucleoplasm Nucleoli "HPA029894: " "unprognostic (2.85e-2)" "unprognostic (1.23e-2)" "unprognostic (8.55e-3)" "potential prognostic unfavorable (5.56e-4)" "unprognostic (1.89e-2)" "unprognostic (1.50e-1)" "unprognostic (2.84e-2)" "unprognostic (6.82e-2)" "unprognostic (8.37e-2)" "unprognostic (7.51e-2)" "unprognostic (1.36e-2)" "unprognostic (2.60e-2)" "unprognostic (4.75e-2)" "potential prognostic unfavorable (3.75e-4)" "unprognostic (4.74e-2)" "potential prognostic unfavorable (7.84e-4)" "unprognostic (2.37e-3)" "validated prognostic unfavorable (3.31e-4)" "validated prognostic unfavorable (2.12e-5)" "unprognostic (1.27e-2)" "unprognostic (2.42e-1)" "unprognostic (1.11e-2)" "unprognostic (3.17e-3)" "unprognostic (2.16e-1)" "unprognostic (1.85e-2)" "unprognostic (4.73e-1)" "unprognostic (3.06e-2)" "unprognostic (7.98e-2)" "unprognostic (5.39e-2)" "unprognostic (2.68e-1)" "unprognostic (5.17e-2)" IER5L bA247A12.2 ENSG00000188483 "Immediate early response 5 like" Q5T953 9 129175552-129178261 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 43.7" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 157.6;Endometrial luminal cells: 137.1;Endometrial stromal cells: 172.0;Epididymal efferent duct absorptive cells: 106.9;Pericytes: 104.6;Smooth muscle cells: 103.1;Vascular smooth muscle cells: 114.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Liver - Neutrophils" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA021327 Approved Nucleoplasm NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 20: Non-specific - Transcription regulation" 1 Nucleoplasm "HPA021327: " "unprognostic (1.60e-1)" "unprognostic (3.80e-1)" "unprognostic (8.12e-2)" "potential prognostic unfavorable (8.98e-5)" "unprognostic (1.54e-1)" "unprognostic (1.50e-3)" "unprognostic (2.42e-2)" "unprognostic (1.96e-1)" "unprognostic (1.68e-2)" "unprognostic (1.42e-1)" "unprognostic (1.79e-1)" "unprognostic (4.46e-2)" "unprognostic (8.62e-3)" "unprognostic (2.41e-3)" "unprognostic (2.36e-1)" "potential prognostic unfavorable (7.67e-5)" "unprognostic (6.67e-2)" "potential prognostic unfavorable (3.71e-4)" "unprognostic (1.35e-1)" "unprognostic (7.04e-3)" "unprognostic (2.30e-1)" "unprognostic (4.62e-1)" "unprognostic (8.98e-2)" "unprognostic (7.19e-2)" "unprognostic (1.47e-2)" "unprognostic (4.70e-2)" "unprognostic (1.41e-2)" "unprognostic (6.41e-3)" "unprognostic (1.22e-1)" "unprognostic (5.48e-2)" "unprognostic (2.42e-3)" IFFO1 "HOM-TES-103, IFFO" ENSG00000010295 "Intermediate filament family orphan 1" Q0D2I5 12 6538961-6556073 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Microglia: 43.8;Sertoli cells: 34.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "skin cancer: 10.8" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069344 Approved NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 9 "HPA069344: " "unprognostic (1.41e-1)" "unprognostic (5.91e-2)" "unprognostic (9.16e-3)" "unprognostic (9.27e-2)" "unprognostic (1.66e-1)" "unprognostic (1.85e-1)" "unprognostic (9.08e-2)" "unprognostic (9.84e-3)" "unprognostic (8.11e-2)" "unprognostic (1.81e-2)" "unprognostic (9.43e-2)" "unprognostic (5.30e-3)" "unprognostic (4.45e-1)" "unprognostic (1.67e-1)" "unprognostic (9.06e-3)" "unprognostic (7.00e-2)" "unprognostic (8.28e-3)" "unprognostic (4.46e-2)" "unprognostic (8.74e-2)" "unprognostic (4.76e-2)" "potential prognostic favorable (2.28e-4)" "unprognostic (9.32e-3)" "unprognostic (8.26e-2)" "unprognostic (5.28e-2)" "unprognostic (7.35e-3)" "unprognostic (1.34e-2)" "unprognostic (7.08e-2)" "unprognostic (1.64e-1)" "unprognostic (1.52e-2)" IFFO2 ENSG00000169991 "Intermediate filament family orphan 2" Q5TF58 1 18904280-18956676 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 161.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 260.5;Esophageal apical cells: 375.6;Esophageal suprabasal cells: 158.1;Innate lymphoid cells: 140.3;Respiratory basal cells: 182.8;Salivary basal cells: 155.2;Salivary myoepithelial cells: 187.4;Suprabasal keratinocytes: 215.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Head and Neck Squamous Cell Carcinoma (TCGA): 49.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 18 "basophil: 12.6" "Lineage enriched" "Detected in single" 18 "granulocytes: 12.6" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Breast myoepithelial cells, Prostate - Smooth muscle cells, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015987, HPA064603" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 58: Skin - Keratinization" "Cluster 25: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 6 "Nucleoplasm, Plasma membrane" "HPA015987: , HPA064603: " "unprognostic (2.78e-2)" "unprognostic (4.93e-1)" "unprognostic (1.71e-1)" "unprognostic (3.22e-1)" "unprognostic (6.00e-2)" "unprognostic (3.60e-2)" "unprognostic (1.80e-1)" "unprognostic (3.34e-1)" "unprognostic (9.92e-2)" "unprognostic (1.38e-2)" "potential prognostic favorable (3.95e-6)" "unprognostic (1.67e-2)" "unprognostic (5.62e-2)" "unprognostic (1.10e-2)" "unprognostic (5.99e-2)" "unprognostic (9.96e-2)" "unprognostic (3.26e-2)" "unprognostic (1.12e-1)" "unprognostic (1.95e-1)" "unprognostic (5.48e-3)" "unprognostic (1.56e-2)" "unprognostic (1.27e-3)" "unprognostic (5.96e-2)" "unprognostic (1.30e-1)" "unprognostic (2.12e-1)" "unprognostic (4.48e-3)" "unprognostic (9.68e-2)" "unprognostic (3.23e-2)" "unprognostic (5.60e-2)" "unprognostic (1.12e-1)" "unprognostic (3.25e-2)" IFI16 "IFNGIP1, PYHIN2" ENSG00000163565 "Interferon gamma inducible protein 16" Q16666 1 158999968-159055155 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Autophagy, Immunity, Inflammatory response, Innate immunity, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 601.2;Hofbauer cells: 412.5;Microglia: 411.3;Neutrophils: 683.1;Vascular endothelial cells: 470.4" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 504.5;endothelial cell: 198.1;leukocyte: 347.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells, Skeletal muscle - Endothelial cells" "HPA002134, CAB016293, HPA073514" Enhanced Supported Nucleoplasm,Nucleoli,Cytosol No No "Cluster 14: Non-specific - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 154 "Nucleoplasm, Nucleoli" Cytosol "CAB016293: , HPA002134: , HPA073514: " "unprognostic (6.91e-2)" "unprognostic (9.73e-2)" "unprognostic (1.77e-1)" "unprognostic (3.15e-1)" "unprognostic (2.20e-1)" "unprognostic (1.80e-1)" "unprognostic (2.24e-1)" "unprognostic (1.31e-1)" "unprognostic (1.49e-1)" "unprognostic (2.83e-1)" "unprognostic (2.43e-3)" "unprognostic (1.42e-1)" "potential prognostic unfavorable (6.16e-5)" "unprognostic (2.28e-1)" "unprognostic (1.07e-1)" "unprognostic (1.28e-1)" "potential prognostic unfavorable (9.33e-4)" "unprognostic (1.77e-1)" "unprognostic (6.23e-2)" "unprognostic (1.69e-1)" "unprognostic (2.03e-2)" "unprognostic (1.18e-2)" "unprognostic (5.29e-2)" "unprognostic (1.27e-1)" "unprognostic (5.58e-2)" "unprognostic (1.07e-1)" "unprognostic (2.42e-1)" "unprognostic (2.00e-1)" "unprognostic (3.69e-1)" "unprognostic (2.74e-1)" "unprognostic (1.16e-1)" IFI27 "FAM14D, ISG12, P27" ENSG00000165949 "Interferon alpha inducible protein 27" P40305 14 94104836-94116695 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Antiviral defense, Apoptosis, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 2261.0;Endometrial ciliated cells: 782.0;Endometrial luminal cells: 602.4;Enterocytes: 2187.3;Esophageal apical cells: 1234.6;Esophageal suprabasal cells: 809.6;Foveolar cells: 1146.0;Gastric progenitor cells: 1611.1;Goblet cells: 1558.6;Vascular endothelial cells: 1122.0" "Cell type enriched" "Detected in many" 7 "endothelial cell: 904.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 8.2" "Group enriched" "Detected in many" 5 "monocytes: 8.2;T-cells: 3.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 766.6" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Minor Salivary Gland - Endothelial cells, Prostate - Endothelial cells, Stomach - Gastric mucous cells" HPA028875 Uncertain NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 5: Spleen - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 1 "HPA028875: " "unprognostic (3.61e-1)" "unprognostic (1.77e-1)" "unprognostic (3.91e-1)" "unprognostic (9.54e-2)" "unprognostic (2.64e-1)" "unprognostic (1.71e-1)" "unprognostic (1.64e-1)" "unprognostic (7.07e-2)" "unprognostic (2.38e-2)" "unprognostic (5.57e-2)" "unprognostic (5.49e-2)" "unprognostic (1.79e-1)" "unprognostic (2.78e-2)" "unprognostic (3.01e-3)" "potential prognostic favorable (3.70e-4)" "unprognostic (2.54e-1)" "unprognostic (2.50e-2)" "unprognostic (9.06e-3)" "unprognostic (1.15e-1)" "unprognostic (1.94e-2)" "unprognostic (8.09e-2)" "unprognostic (1.48e-3)" "unprognostic (5.94e-2)" "unprognostic (8.75e-2)" "unprognostic (1.14e-1)" "unprognostic (9.28e-2)" "unprognostic (2.23e-1)" "unprognostic (4.60e-2)" "unprognostic (1.40e-1)" "unprognostic (1.12e-1)" "unprognostic (1.67e-1)" IFI27L1 FAM14B ENSG00000165948 "Interferon alpha inducible protein 27 like 1" Q96BM0 14 94081301-94103846 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 86.0;testis: 98.2" "Cell type enhanced" "Detected in many" "Early spermatids: 279.1;Granulosa cells: 158.1;Late primary spermatocytes: 210.2;Late spermatids: 176.0;Platelets: 169.0;Sertoli cells: 82.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 16.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skin - Fibroblasts_1, Stomach - Gastric mucous cells, Testis - Sertoli cells" "Intracellular and membrane" Other NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" "unprognostic (3.27e-3)" "potential prognostic favorable (6.80e-4)" "unprognostic (4.21e-2)" "unprognostic (1.53e-2)" "unprognostic (9.47e-2)" "unprognostic (1.02e-1)" "unprognostic (7.68e-2)" "unprognostic (1.41e-1)" "unprognostic (3.94e-2)" "unprognostic (4.24e-2)" "unprognostic (1.01e-1)" "unprognostic (2.52e-1)" "potential prognostic favorable (5.49e-4)" "unprognostic (2.61e-3)" "unprognostic (2.38e-1)" "unprognostic (1.18e-1)" "unprognostic (3.89e-2)" "unprognostic (2.91e-1)" "unprognostic (2.31e-1)" "unprognostic (1.58e-2)" "unprognostic (1.69e-1)" "unprognostic (1.88e-1)" "unprognostic (4.22e-1)" "unprognostic (2.19e-1)" "unprognostic (1.85e-2)" "unprognostic (6.74e-2)" "unprognostic (2.42e-1)" "unprognostic (1.26e-1)" "unprognostic (2.71e-1)" "unprognostic (1.04e-1)" "unprognostic (2.49e-1)" IFI27L2 "FAM14A, TLH29" ENSG00000119632 "Interferon alpha inducible protein 27 like 2" Q9H2X8 14 94127779-94130253 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 257.0;Megakaryocytes: 513.1;Melanocytes: 250.0;Platelets: 395.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" HPA049588 Approved Nucleoli,Cytosol "Intracellular and membrane" Other No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 47: Platelets - Hemostasis" Cytosol Nucleoli "HPA049588: " "unprognostic (2.05e-2)" "unprognostic (1.56e-2)" "unprognostic (2.11e-2)" "unprognostic (3.32e-2)" "unprognostic (4.65e-2)" "unprognostic (1.66e-1)" "unprognostic (1.19e-1)" "unprognostic (2.20e-1)" "unprognostic (2.31e-3)" "unprognostic (5.06e-1)" "unprognostic (6.91e-2)" "unprognostic (9.16e-2)" "unprognostic (8.86e-2)" "unprognostic (6.00e-3)" "unprognostic (2.56e-1)" "unprognostic (5.44e-2)" "unprognostic (1.41e-1)" "unprognostic (2.60e-2)" "unprognostic (8.05e-2)" "unprognostic (5.03e-2)" "unprognostic (1.93e-1)" "unprognostic (3.51e-2)" "unprognostic (1.13e-1)" "unprognostic (2.70e-2)" "unprognostic (2.02e-1)" "unprognostic (2.01e-1)" "unprognostic (3.17e-1)" "unprognostic (2.24e-1)" "unprognostic (3.68e-1)" "unprognostic (1.46e-1)" "unprognostic (2.40e-2)" IFI30 "GILT, IFI-30, IP-30, IP30, MGC32056" ENSG00000216490 "IFI30 lysosomal thiol reductase" P13284 19 18173162-18178117 "Predicted intracellular proteins, Predicted membrane proteins" Immunity Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 539.6;lymphoid tissue: 668.3" "Group enriched" "Detected in some" 10 "Microglia: 26.8;monocytes: 26.6" "Group enriched" "Detected in some" 5 "central nervous system macrophage: 45.3;leukocyte: 88.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 9529.3;eosinophil: 3901.6;intermediate monocyte: 14264.3;myeloid DC: 5706.8;non-classical monocyte: 9916.5" "Group enriched" "Detected in all" 8 "dendritic cells: 5706.8;granulocytes: 3901.6;monocytes: 14264.3" "Cancer enhanced" "Detected in all" "lymphoma: 572.2" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Lung - Macrophages, Skeletal muscle - Macrophages, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026650 Enhanced Supported Vesicles,Cytosol "Intracellular and membrane" Immunity NA NA 260000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 55: Lymphoma - Immune response" "Cluster 102: Non-specific - Mixed function" 20 "Vesicles, Cytosol" "HPA026650: " "unprognostic (6.06e-2)" "unprognostic (7.57e-2)" "unprognostic (8.34e-2)" "potential prognostic favorable (8.16e-5)" "unprognostic (2.59e-1)" "unprognostic (1.25e-1)" "unprognostic (1.53e-3)" "unprognostic (1.66e-1)" "unprognostic (1.04e-1)" "unprognostic (5.90e-2)" "unprognostic (4.46e-2)" "unprognostic (1.04e-1)" "unprognostic (1.47e-2)" "unprognostic (1.43e-2)" "unprognostic (2.48e-2)" "unprognostic (8.82e-2)" "unprognostic (7.31e-2)" "unprognostic (1.53e-1)" "unprognostic (4.51e-2)" "unprognostic (1.21e-2)" "unprognostic (9.23e-2)" "unprognostic (1.97e-2)" "unprognostic (3.97e-2)" "unprognostic (2.04e-1)" "potential prognostic unfavorable (5.38e-4)" "unprognostic (1.18e-1)" "unprognostic (9.32e-3)" "unprognostic (9.13e-2)" "unprognostic (4.90e-3)" "unprognostic (6.68e-2)" "unprognostic (1.25e-1)" IFI35 IFP35 ENSG00000068079 "Interferon induced protein 35" P80217 17 43006740-43014456 "Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 73.1;Decidual stromal cells: 85.3;Enterocytes: 117.0;Granulosa cells: 84.3;Hofbauer cells: 111.1" "Cell type enhanced" "Detected in many" "endothelial cell: 42.6;pericyte: 25.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003283, HPA045946, HPA075580" Approved Supported Nucleoplasm,Nucleoli,Cytosol "Secreted to blood" Immunity NA NA 45000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 28: Liver & Adrenal gland - Secretion" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 7 "Nucleoplasm, Cytosol" Nucleoli "HPA003283: , HPA045946: , HPA075580: " "unprognostic (2.39e-1)" "unprognostic (4.66e-3)" "unprognostic (2.63e-1)" "unprognostic (2.93e-2)" "unprognostic (5.44e-2)" "unprognostic (1.06e-2)" "unprognostic (3.43e-2)" "unprognostic (1.14e-1)" "unprognostic (3.43e-1)" "unprognostic (1.62e-1)" "unprognostic (1.17e-1)" "unprognostic (1.23e-1)" "unprognostic (4.05e-2)" "potential prognostic unfavorable (8.68e-4)" "unprognostic (3.44e-2)" "potential prognostic unfavorable (6.46e-4)" "unprognostic (1.50e-2)" "unprognostic (1.36e-1)" "unprognostic (2.72e-1)" "unprognostic (7.21e-2)" "unprognostic (4.25e-2)" "potential prognostic unfavorable (1.15e-4)" "unprognostic (9.15e-2)" "unprognostic (9.01e-2)" "unprognostic (1.86e-2)" "unprognostic (2.06e-2)" "unprognostic (2.07e-1)" "unprognostic (9.03e-2)" "unprognostic (1.48e-2)" "unprognostic (4.99e-2)" "unprognostic (3.09e-1)" IFI44 "MTAP44, p44, TLDC5" ENSG00000137965 "Interferon induced protein 44" Q8TCB0 1 78649796-78664078 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 95.3" "Cell type enhanced" "Detected in many" "Innate lymphoid cells: 54.4;Kupffer cells: 63.5;Macrophages: 61.9;Microglia: 56.6;Oligodendrocyte progenitor cells: 77.0;Thymocytes: 54.2;Vascular endothelial cells: 79.3" "Cell type enhanced" "Detected in many" "endothelial cell: 281.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA027148, HPA043858" Approved Approved Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 104: Brain endothelial cells - Blood brain barrier" 1 Nucleoplasm "HPA027148: , HPA043858: " "unprognostic (2.82e-1)" "unprognostic (2.50e-1)" "unprognostic (9.82e-2)" "unprognostic (4.89e-2)" "unprognostic (1.47e-2)" "unprognostic (2.92e-2)" "unprognostic (3.73e-1)" "unprognostic (1.30e-1)" "unprognostic (8.30e-2)" "unprognostic (1.32e-1)" "potential prognostic unfavorable (5.08e-5)" "unprognostic (1.78e-1)" "unprognostic (1.65e-1)" "unprognostic (1.56e-2)" "unprognostic (1.16e-2)" "unprognostic (3.66e-2)" "unprognostic (3.61e-2)" "unprognostic (1.55e-1)" "unprognostic (6.36e-2)" "unprognostic (1.57e-1)" "unprognostic (1.38e-2)" "unprognostic (4.12e-3)" "unprognostic (7.18e-3)" "unprognostic (4.06e-1)" "unprognostic (1.60e-1)" "unprognostic (1.59e-3)" "unprognostic (8.44e-2)" "unprognostic (1.83e-1)" "unprognostic (1.57e-3)" "unprognostic (1.31e-1)" "unprognostic (3.61e-2)" IFI44L "C1orf29, GS3686, TLDC5B" ENSG00000137959 "Interferon induced protein 44 like" Q53G44 1 78619902-78646145 "Predicted intracellular proteins" "Antiviral defense" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 75.8" "Cell type enhanced" "Detected in many" "Granulosa cells: 105.4;Macrophages: 72.0;Microglia: 143.9;Ovarian stromal cells: 47.0;pDCs: 45.2;Peritubular myoid cells: 63.8;Pituicytes/FSCs: 51.8;Thymocytes: 109.3;Vascular endothelial cells: 116.6" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 199.7;endothelial cell: 501.3;fibroblast: 191.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Prostate - Fibroblasts, Testis - Peritubular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA053247, HPA060372" Uncertain Approved Nucleoplasm NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 104: Brain endothelial cells - Blood brain barrier" Nucleoplasm "HPA053247: , HPA060372: " "unprognostic (6.76e-2)" "unprognostic (2.91e-1)" "unprognostic (5.33e-1)" "unprognostic (2.64e-1)" "unprognostic (2.42e-2)" "unprognostic (9.95e-2)" "unprognostic (4.47e-3)" "unprognostic (6.26e-2)" "unprognostic (2.27e-1)" "unprognostic (1.25e-1)" "unprognostic (1.62e-2)" "unprognostic (3.17e-2)" "unprognostic (4.42e-3)" "unprognostic (1.34e-2)" "unprognostic (6.11e-2)" "unprognostic (1.48e-2)" "unprognostic (1.54e-3)" "unprognostic (8.54e-3)" "unprognostic (2.11e-1)" "unprognostic (3.66e-1)" "unprognostic (1.18e-2)" "unprognostic (4.33e-3)" "potential prognostic unfavorable (1.96e-4)" "unprognostic (1.25e-1)" "unprognostic (2.53e-1)" "potential prognostic favorable (5.00e-4)" "unprognostic (2.24e-1)" "unprognostic (3.90e-2)" "unprognostic (2.46e-3)" "unprognostic (3.03e-1)" "unprognostic (3.60e-2)" IFI6 "6-16, FAM14C, G1P3, IFI-6-16, IFI616" ENSG00000126709 "Interferon alpha inducible protein 6" P09912 1 27666064-27672212 "Predicted membrane proteins" "Antiviral defense, Apoptosis, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 11 "choroid plexus: 3349.7" "Group enriched" "Detected in many" 5 "Cytotrophoblasts: 2859.5;Extravillous trophoblasts: 912.7;Migrating cytotrophoblasts: 2580.1;Syncytiotrophoblasts: 2989.4" "Cell type enhanced" "Detected in all" "endothelial cell: 200.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts, Skin - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in all" HPA005543 Approved Supported Mitochondria NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 1 Mitochondria "HPA005543: " "unprognostic (2.80e-1)" "unprognostic (3.82e-1)" "unprognostic (7.35e-2)" "unprognostic (1.45e-1)" "unprognostic (7.22e-3)" "unprognostic (1.01e-1)" "unprognostic (2.93e-1)" "unprognostic (4.68e-2)" "unprognostic (2.12e-2)" "unprognostic (3.20e-2)" "unprognostic (5.67e-2)" "unprognostic (1.95e-1)" "unprognostic (1.75e-1)" "unprognostic (3.21e-2)" "unprognostic (1.26e-1)" "unprognostic (7.24e-2)" "unprognostic (1.03e-1)" "unprognostic (3.99e-2)" "unprognostic (2.21e-1)" "unprognostic (4.75e-2)" "unprognostic (1.67e-1)" "unprognostic (4.40e-2)" "unprognostic (3.82e-1)" "unprognostic (8.83e-2)" "unprognostic (1.55e-1)" "unprognostic (4.88e-3)" "unprognostic (2.20e-1)" "unprognostic (1.20e-1)" "unprognostic (8.65e-2)" "unprognostic (7.91e-2)" "unprognostic (1.64e-1)" IFIH1 "Hlcd, IDDM19, MDA-5, MDA5" ENSG00000115267 "Interferon induced with helicase C domain 1" Q9BYX4 2 162267074-162318684 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" "Helicase, Hydrolase, RNA-binding" "Aicardi-Goutieres syndrome, Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 34.6" "Cell type enhanced" "Detected in many" "Early spermatids: 88.5;Late spermatids: 93.1;Neutrophils: 129.2" "Cell type enhanced" "Detected in many" "endothelial cell: 118.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002656 Approved NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 16 "HPA002656: " "unprognostic (5.74e-2)" "unprognostic (1.01e-1)" "unprognostic (3.87e-2)" "unprognostic (1.28e-1)" "unprognostic (3.71e-1)" "unprognostic (1.01e-2)" "unprognostic (1.55e-1)" "unprognostic (9.65e-3)" "unprognostic (1.40e-1)" "unprognostic (1.35e-2)" "potential prognostic favorable (2.65e-8)" "unprognostic (1.35e-2)" "unprognostic (4.96e-2)" "unprognostic (1.77e-1)" "unprognostic (5.39e-2)" "unprognostic (6.10e-2)" "unprognostic (1.72e-2)" "unprognostic (1.71e-1)" "unprognostic (1.44e-1)" "unprognostic (3.47e-1)" "unprognostic (1.67e-1)" "unprognostic (1.43e-3)" "unprognostic (9.44e-3)" "unprognostic (2.99e-1)" "unprognostic (1.53e-2)" "unprognostic (2.89e-2)" "unprognostic (1.93e-1)" "unprognostic (1.02e-1)" "unprognostic (8.90e-2)" "unprognostic (6.57e-2)" "unprognostic (2.63e-2)" IFIT1 "G10P1, GARG-16, IFI56, IFNAI1" ENSG00000185745 "Interferon induced protein with tetratricopeptide repeats 1" P09914 10 89392546-89406487 "Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal basal cells: 63.4;Epididymal efferent duct ciliated cells: 64.2;Hofbauer cells: 61.3;Müller glia: 76.1" "Cell type enhanced" "Detected in all" "endothelial cell: 106.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 67.0" "Group enriched" "Detected in all" 8 "granulocytes: 67.0;monocytes: 21.7" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Prostate - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "CAB045980, HPA053890, HPA055380, CAB080338" Supported Enhanced Cytosol NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 10 Cytosol "CAB045980: , CAB080338: , HPA053890: , HPA055380: " "unprognostic (1.20e-1)" "unprognostic (4.71e-2)" "unprognostic (2.18e-2)" "unprognostic (1.69e-1)" "unprognostic (4.93e-2)" "unprognostic (8.93e-2)" "unprognostic (4.72e-3)" "unprognostic (1.80e-2)" "unprognostic (2.12e-2)" "unprognostic (1.16e-1)" "potential prognostic favorable (3.60e-6)" "unprognostic (3.36e-2)" "potential prognostic favorable (2.60e-4)" "unprognostic (1.09e-1)" "unprognostic (4.46e-3)" "unprognostic (1.74e-1)" "unprognostic (1.65e-2)" "unprognostic (2.32e-1)" "unprognostic (2.73e-1)" "unprognostic (1.16e-1)" "unprognostic (9.48e-2)" "unprognostic (9.89e-3)" "unprognostic (2.61e-3)" "unprognostic (1.85e-1)" "unprognostic (5.09e-1)" "unprognostic (2.18e-3)" "unprognostic (2.00e-1)" "unprognostic (8.91e-3)" "unprognostic (6.69e-2)" "unprognostic (1.08e-1)" "unprognostic (3.32e-2)" IFIT1B "bA149I23.6, IFIT1L" ENSG00000204010 "Interferon induced protein with tetratricopeptide repeats 1B" Q5T764 10 89378056-89385205 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "bone marrow: 24.2" "Cell type enriched" "Detected in some" 19 "Erythrocytes: 134.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Erythroid cells, Spleen - Erythrocytes" "Low region specificity" "Detected in all" HPA062924 Approved NA NA "Cluster 15: Bone marrow - Innate immune response" "Cluster 5: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 3 "HPA062924: " IFIT2 "cig42, G10P2, GARG-39, IFI-54, IFI54, ISG-54, ISG-54K" ENSG00000119922 "Interferon induced protein with tetratricopeptide repeats 2" P09913 10 89283694-89309271 "Predicted intracellular proteins" "Antiviral defense, Apoptosis, Immunity, Innate immunity" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 45.8" "Cell type enhanced" "Detected in many" "Endometrial luminal cells: 170.9;Epididymal basal cells: 116.0;Epididymal clear cells: 240.9;Epididymal efferent duct ciliated cells: 62.5;Kupffer cells: 76.9;pDCs: 469.4" "Cell type enhanced" "Detected in all" "oligodendrocyte: 33.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 421.4" "Lineage enriched" "Detected in all" 5 "granulocytes: 421.4" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - T-cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003408 Approved Approved Vesicles NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 30: White matter - Myelination" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 20: Non-specific - Transcription regulation" 7 Vesicles "HPA003408: " "unprognostic (4.23e-1)" "unprognostic (1.49e-1)" "unprognostic (4.11e-2)" "unprognostic (1.38e-1)" "unprognostic (4.66e-2)" "unprognostic (6.57e-2)" "unprognostic (1.73e-1)" "potential prognostic favorable (3.22e-4)" "unprognostic (1.60e-1)" "unprognostic (8.98e-2)" "unprognostic (2.79e-2)" "unprognostic (3.29e-1)" "unprognostic (3.55e-2)" "unprognostic (1.15e-2)" "potential prognostic favorable (2.63e-6)" "unprognostic (2.49e-1)" "unprognostic (3.37e-2)" "unprognostic (3.39e-1)" "unprognostic (6.96e-2)" "unprognostic (2.89e-1)" "unprognostic (2.01e-1)" "unprognostic (2.07e-3)" "unprognostic (1.92e-2)" "unprognostic (2.12e-1)" "unprognostic (2.11e-1)" "unprognostic (7.52e-2)" "unprognostic (4.68e-2)" "unprognostic (1.09e-2)" "unprognostic (5.83e-2)" "unprognostic (1.59e-2)" "unprognostic (2.45e-3)" IFIT3 "CIG-49, GARG-49, IFI60, IFIT4, IRG2, ISG60, RIG-G" ENSG00000119917 "Interferon induced protein with tetratricopeptide repeats 3" O14879 10 89327307-89377473 "Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial luminal cells: 76.1;Epididymal basal cells: 413.1;Epididymal clear cells: 102.1;Epididymal efferent duct ciliated cells: 114.2;Oligodendrocytes: 75.8;Schwann cells: 75.8" "Cell type enhanced" "Detected in all" "oligodendrocyte: 115.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 489.5" "Group enriched" "Detected in all" 19 "granulocytes: 489.5;monocytes: 125.2" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" HPA059914 Approved Supported Mitochondria,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 30: White matter - Myelination" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 23 "Mitochondria, Cytosol" "HPA059914: " "unprognostic (1.78e-1)" "unprognostic (2.57e-1)" "unprognostic (1.32e-1)" "unprognostic (1.50e-1)" "unprognostic (1.50e-1)" "unprognostic (5.48e-2)" "unprognostic (4.79e-2)" "unprognostic (5.47e-2)" "unprognostic (8.69e-2)" "unprognostic (2.45e-1)" "potential prognostic favorable (3.05e-4)" "unprognostic (1.12e-2)" "unprognostic (1.51e-1)" "unprognostic (1.60e-1)" "unprognostic (1.83e-3)" "unprognostic (9.76e-2)" "unprognostic (1.43e-2)" "unprognostic (9.49e-2)" "unprognostic (2.72e-1)" "unprognostic (1.88e-1)" "unprognostic (5.75e-2)" "unprognostic (1.94e-3)" "unprognostic (1.33e-2)" "unprognostic (2.41e-1)" "unprognostic (1.51e-1)" "unprognostic (3.51e-2)" "unprognostic (4.20e-2)" "unprognostic (1.42e-1)" "unprognostic (6.13e-2)" "unprognostic (1.48e-2)" "unprognostic (5.81e-3)" IFIT5 RI58 ENSG00000152778 "Interferon induced protein with tetratricopeptide repeats 5" Q13325 10 89414568-89421605 "Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" "RNA-binding, tRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 39.5;Epididymal basal cells: 47.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "HPA037957, HPA062180" Uncertain Supported "Plasma membrane" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 61: Non-specific - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 11 "Plasma membrane" "HPA037957: , HPA062180: " "unprognostic (1.29e-1)" "unprognostic (3.52e-1)" "unprognostic (1.53e-1)" "unprognostic (8.48e-2)" "unprognostic (7.64e-2)" "unprognostic (1.14e-1)" "unprognostic (3.86e-2)" "unprognostic (3.67e-3)" "unprognostic (2.52e-2)" "unprognostic (2.72e-1)" "potential prognostic favorable (9.32e-8)" "unprognostic (1.85e-3)" "unprognostic (5.93e-2)" "unprognostic (1.37e-2)" "unprognostic (5.30e-3)" "unprognostic (2.03e-1)" "unprognostic (5.40e-2)" "unprognostic (3.10e-1)" "unprognostic (1.83e-1)" "unprognostic (2.21e-1)" "unprognostic (7.40e-2)" "unprognostic (4.41e-2)" "unprognostic (6.32e-3)" "unprognostic (8.19e-2)" "unprognostic (6.20e-2)" "unprognostic (1.85e-2)" "unprognostic (1.86e-1)" "unprognostic (1.35e-1)" "unprognostic (2.37e-2)" "unprognostic (1.25e-1)" "unprognostic (2.78e-1)" IFITM1 "9-27, CD225, DSPA2a, IFI17" ENSG00000185885 "Interferon induced transmembrane protein 1" P13164 11 310041-315272 "CD markers, Plasma proteins, Predicted membrane proteins, Transporters" "Antiviral defense, Immunity, Innate immunity, Osteogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 121.3;Endometrial secretory cells: 263.5;Epididymal efferent duct absorptive cells: 358.1;Epididymal principal cells: 250.8;Fallopian secretory cells: 105.2;Leydig cells: 177.0;Neutrophils: 238.3;NK-cells: 153.3;Ovarian stromal cells: 173.1;Pericytes: 163.2;T-cells: 105.8;Vascular endothelial cells: 154.4" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "eosinophil: 1500.1;gdT-cell: 2915.2;MAIT T-cell: 2008.6;memory CD4 T-cell: 3131.5;memory CD8 T-cell: 3002.0;naive CD4 T-cell: 2949.8;naive CD8 T-cell: 3007.1;neutrophil: 2758.0;NK-cell: 4694.8;T-reg: 1950.8" "Group enriched" "Detected in all" 7 "granulocytes: 2758.0;NK-cells: 4694.8;T-cells: 3131.5" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells, Minor Salivary Gland - Endothelial cells, Skeletal muscle - Endothelial cells" "HPA004810, CAB017615" Enhanced Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 22: Epididymis - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 36 "Golgi apparatus, Plasma membrane" "CAB017615: , HPA004810: " "unprognostic (2.90e-1)" "unprognostic (2.71e-3)" "unprognostic (7.60e-2)" "unprognostic (8.33e-2)" "unprognostic (1.38e-1)" "unprognostic (7.76e-2)" "unprognostic (7.24e-2)" "unprognostic (9.56e-2)" "unprognostic (3.54e-1)" "unprognostic (8.98e-2)" "unprognostic (2.04e-3)" "unprognostic (3.38e-1)" "potential prognostic unfavorable (2.43e-5)" "unprognostic (1.06e-1)" "unprognostic (8.64e-3)" "unprognostic (9.45e-2)" "unprognostic (4.53e-1)" "unprognostic (2.86e-1)" "unprognostic (3.81e-1)" "unprognostic (2.23e-1)" "unprognostic (1.15e-1)" "unprognostic (2.78e-3)" "unprognostic (1.55e-3)" "unprognostic (5.94e-2)" "unprognostic (2.46e-2)" "unprognostic (2.38e-1)" "unprognostic (6.09e-2)" "unprognostic (2.02e-1)" "unprognostic (6.49e-2)" "unprognostic (1.03e-1)" "unprognostic (2.50e-1)" IFITM10 DSPA3 ENSG00000244242 "Interferon induced transmembrane protein 10" A6NMD0 11 1732406-1750595 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 2.4;bone marrow: 1.4;retina: 1.3" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 9.9;Brain inhibitory neurons: 8.0;Microglia: 6.8;Oligodendrocyte progenitor cells: 31.1;Oligodendrocytes: 3.2;Other brain neurons: 10.8;Papillary tip epithelial cells: 3.6" "Cell type enhanced" "Detected in many" "oligodendrocyte precursor cell: 40.6" "Cancer enhanced" "Detected in some" "Bladder Urothelial Carcinoma (TCGA): 1.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 4.3;Kidney cancer: 4.1" "Prostate - Urothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 2: Neurons - Nucleosome" "Cluster 15: Kidney cancer - Membrane components" "Cluster 98: Neurons - Neurotransmission & signaling" "unprognostic (1.69e-1)" "unprognostic (3.00e-2)" "unprognostic (4.31e-3)" "unprognostic (4.33e-2)" "unprognostic (3.93e-1)" "unprognostic (1.92e-2)" IFITM2 "1-8D, DSPA2c" ENSG00000185201 "Interferon induced transmembrane protein 2" Q01629 11 303655-309397 "Predicted membrane proteins, Transporters" "Antiviral defense, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 10 "Neutrophils: 3450.7" "Group enriched" "Detected in some" 35 "endothelial cell: 478.9;fibroblast: 238.1;leukocyte: 341.7;pericyte: 790.1;vascular associated smooth muscle cell: 237.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 6 "neutrophil: 23257.9" "Lineage enriched" "Detected in all" 11 "granulocytes: 23257.9" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells, Spleen - Neutrophils_2" "HPA004337, HPA044731" Uncertain Approved "Nucleoplasm,Cell Junctions" NA NA 40000 "Cluster 21: Neutrophils - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 8: Immune cells - Immune response" "Cluster 35: RS4;11 - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" "Cell Junctions" Nucleoplasm "HPA004337: , HPA044731: " "unprognostic (1.01e-1)" "unprognostic (3.30e-2)" "unprognostic (2.75e-2)" "unprognostic (1.20e-1)" "unprognostic (1.68e-1)" "unprognostic (3.22e-1)" "unprognostic (2.97e-2)" "potential prognostic unfavorable (1.70e-4)" "unprognostic (3.59e-2)" "unprognostic (1.36e-1)" "unprognostic (1.51e-2)" "unprognostic (8.39e-2)" "unprognostic (1.23e-2)" "potential prognostic unfavorable (6.71e-4)" "potential prognostic favorable (3.99e-4)" "unprognostic (1.25e-1)" "unprognostic (2.24e-3)" "unprognostic (6.19e-3)" "unprognostic (1.59e-1)" "unprognostic (3.74e-2)" "unprognostic (2.28e-2)" "potential prognostic unfavorable (7.27e-4)" "unprognostic (1.77e-1)" "unprognostic (6.84e-2)" "unprognostic (4.36e-2)" "unprognostic (2.86e-2)" "unprognostic (2.42e-1)" "unprognostic (2.60e-2)" "unprognostic (6.99e-3)" "unprognostic (1.67e-1)" "unprognostic (1.86e-1)" IFITM3 "1-8U, DSPA2b" ENSG00000142089 "Interferon induced transmembrane protein 3" Q01628 11 319676-329475 "Essential proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiviral defense, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 3819.7;Epididymal efferent duct absorptive cells: 1851.4;Epididymal principal cells: 1558.5;Fallopian secretory cells: 2246.4;Fibroblasts: 1347.2;Hepatic stellate cells: 1678.2;Hepatocytes: 1916.7;Leydig cells: 1398.5;Pericytes: 1348.9;Vascular endothelial cells: 1570.1" "Group enriched" "Detected in many" 7 "endothelial cell: 492.4;fibroblast: 222.7;pericyte: 688.4;vascular associated smooth muscle cell: 336.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 2953.0;non-classical monocyte: 3364.2" "Group enriched" "Detected in all" 6 "granulocytes: 2953.0;monocytes: 3364.2;NK-cells: 928.9" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells" HPA004337 Uncertain NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 8: Immune cells - Immune response" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 116 "HPA004337: " "unprognostic (8.33e-2)" "unprognostic (1.88e-2)" "unprognostic (2.16e-1)" "unprognostic (5.13e-2)" "unprognostic (2.64e-1)" "unprognostic (5.53e-2)" "unprognostic (4.08e-3)" "potential prognostic unfavorable (1.19e-4)" "unprognostic (8.72e-3)" "unprognostic (3.09e-2)" "unprognostic (4.25e-2)" "unprognostic (6.10e-2)" "unprognostic (1.98e-1)" "unprognostic (1.74e-2)" "unprognostic (3.47e-2)" "unprognostic (1.01e-2)" "unprognostic (8.03e-2)" "unprognostic (1.88e-2)" "unprognostic (1.67e-2)" "unprognostic (9.88e-2)" "unprognostic (2.25e-1)" "unprognostic (3.02e-2)" "unprognostic (2.86e-2)" "unprognostic (4.82e-2)" "unprognostic (2.50e-1)" "unprognostic (3.21e-1)" "unprognostic (3.97e-2)" "unprognostic (1.23e-1)" "unprognostic (5.24e-2)" "unprognostic (1.57e-1)" "unprognostic (9.24e-2)" IFITM5 "BRIL, DSPA1, fragilis4, Hrmp1" ENSG00000206013 "Interferon induced transmembrane protein 5" A6NNB3 11 298200-299526 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Mineral balance" "Developmental protein" "Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 10 "pancreas: 6.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in some" 7 "cerebral cortex: 10.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA039258 Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 12: Non-specific - Vasculature" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" "Plasma membrane" "Vesicles, Cytosol" "HPA039258: " "unprognostic (1.46e-1)" "unprognostic (4.53e-2)" "unprognostic (1.40e-1)" "unprognostic (1.21e-1)" IFNA1 "IFL, IFN, IFN-ALPHA, IFN-alphaD, IFNA@, IFNA13" ENSG00000197919 "Interferon alpha 1" P01562 9 21440439-21441316 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Antiviral defense" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "cervical cancer: 1.1" HPA047557 Uncertain "Secreted to blood" Interferon NA NA 10000 "Cluster 37: Neurons - Mixed function" "Cluster 56: Non-specific - Sensory perception" 1 "HPA047557: " IFNA10 IFN-alphaC ENSG00000186803 "Interferon alpha 10" P01566 9 21206181-21207143 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047557 Uncertain "Secreted to blood" Interferon NA NA 2 "HPA047557: " IFNA13 ENSG00000233816 "Interferon alpha 13" P01562 9 21367372-21368057 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Antiviral defense" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 6 "Oligodendrocytes: 3.0" "Group enriched" "Detected in some" 6 "committed oligodendrocyte precursor: 1.5;oligodendrocyte: 3.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047557 Uncertain "Secreted to blood" Interferon NA NA "Cluster 11: White matter - Signal transduction" "Cluster 55: Lymphoma - Immune response" "Cluster 102: Non-specific - Mixed function" 1 "HPA047557: " IFNA14 "IFN-alphaH, LEIF2H" ENSG00000228083 "Interferon alpha 14" P01570 9 21239002-21240005 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 891 "pDCs: 89.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047557 Uncertain "Secreted to blood" Interferon NA NA "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 5 "HPA047557: " IFNA16 IFN-alphaO ENSG00000147885 "Interferon alpha 16" P05015 9 21216373-21217311 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047557 Uncertain "Secreted to blood" Interferon NA NA 2 "HPA047557: " IFNA17 "IFN-alphaI, LEIF2C1" ENSG00000234829 "Interferon alpha 17" P01571 9 21227243-21228222 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047557 Uncertain "Secreted to blood" Interferon NA NA "HPA047557: " IFNA2 "IFN-alphaA, IFNA" ENSG00000188379 "Interferon alpha 2" P01563 9 21384255-21385398 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 10 "Oligodendrocytes: 3.2" "Group enriched" "Detected in some" 7 "committed oligodendrocyte precursor: 2.4;oligodendrocyte: 2.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047557 Uncertain "Secreted to blood" Interferon NA NA 253000 "Cluster 11: White matter - Signal transduction" "Cluster 55: Lymphoma - Immune response" "Cluster 80: Oligodendrocytes - Myelination" 4 "HPA047557: " IFNA21 IFN-alphaI ENSG00000137080 "Interferon alpha 21" P01568 9 21165637-21166660 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047557 Uncertain "Secreted to blood" Interferon NA NA "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" 3 "HPA047557: " IFNA4 "IFN-alpha4a, MGC142200" ENSG00000236637 "Interferon alpha 4" P05014 9 21186618-21187587 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047557 Uncertain "Secreted to blood" Interferon NA NA 25 "HPA047557: " IFNA5 IFN-alphaG ENSG00000147873 "Interferon alpha 5" P01569 9 21304326-21305313 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Retinal horizontal cells: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047557 Uncertain "Secreted to blood" Interferon NA NA "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 109: Neurons - Neuronal signaling" 5 "HPA047557: " IFNA6 IFN-alphaK ENSG00000120235 "Interferon alpha 6" P05013 9 21350253-21350956 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047557 Uncertain "Secreted to blood" Interferon NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 80: Oligodendrocytes - Myelination" 1 "HPA047557: " IFNA7 "IFN-alphaJ, IFNA-J" ENSG00000214042 "Interferon alpha 7" P01567 9 21201469-21202205 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047557 Uncertain "Secreted to blood" Interferon NA NA "Cluster 10: Ciliated cells - Ion channel activity" 1 "HPA047557: " IFNA8 IFN-alphaB ENSG00000120242 "Interferon alpha 8" P32881 9 21409117-21410185 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047557 Uncertain "Secreted to blood" Interferon NA NA "Cluster 37: Neurons - Mixed function" "Cluster 4: Non-specific - Transcription" 2 "HPA047557: " IFNAR1 "IFNAR, IFRC" ENSG00000142166 "Interferon alpha and beta receptor subunit 1" P17181 21 33324387-33359864 "Cancer-related genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 432.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029226 Approved NA NA 190000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 27: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 24: Neutrophils - Innate immunity signal integration" 21 "HPA029226: " "unprognostic (1.73e-1)" "unprognostic (1.82e-2)" "unprognostic (3.03e-1)" "unprognostic (1.52e-2)" "unprognostic (2.20e-1)" "unprognostic (1.01e-1)" "unprognostic (2.72e-1)" "unprognostic (3.08e-2)" "unprognostic (7.54e-2)" "unprognostic (1.77e-1)" "potential prognostic favorable (1.49e-5)" "unprognostic (4.36e-3)" "unprognostic (4.55e-2)" "unprognostic (2.01e-1)" "unprognostic (2.28e-1)" "unprognostic (3.13e-1)" "unprognostic (3.13e-2)" "unprognostic (8.42e-3)" "unprognostic (1.05e-1)" "unprognostic (2.09e-1)" "unprognostic (4.18e-2)" "potential prognostic unfavorable (2.94e-4)" "unprognostic (3.83e-1)" "unprognostic (2.10e-1)" "unprognostic (2.30e-1)" "unprognostic (8.54e-2)" "unprognostic (5.99e-2)" "unprognostic (1.28e-1)" "unprognostic (3.50e-1)" "unprognostic (1.32e-1)" "unprognostic (1.98e-1)" IFNAR2 IFNABR ENSG00000159110 "Interferon alpha and beta receptor subunit 2" P48551 21 33205282-33265675 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 36.1;Brain inhibitory neurons: 39.9;Extravillous trophoblasts: 67.3;Microglia: 47.3;Oligodendrocyte progenitor cells: 51.1;Oligodendrocytes: 38.7;pDCs: 36.3;Plasma cells: 73.3" "Cell type enhanced" "Detected in all" "endothelial cell: 336.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Myeloma: 108.5" "Colon - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" Receptor NA NA 700000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 104: Brain endothelial cells - Blood brain barrier" 21 "unprognostic (5.14e-2)" "unprognostic (2.13e-1)" "unprognostic (3.23e-2)" "potential prognostic unfavorable (3.54e-4)" "unprognostic (4.46e-1)" "unprognostic (4.34e-2)" "unprognostic (1.05e-2)" "unprognostic (1.67e-1)" "unprognostic (4.37e-1)" "unprognostic (3.10e-3)" "unprognostic (1.51e-1)" "unprognostic (1.58e-1)" "unprognostic (5.76e-2)" "unprognostic (1.40e-3)" "unprognostic (6.89e-2)" "unprognostic (2.81e-2)" "potential prognostic unfavorable (8.05e-4)" "unprognostic (6.00e-2)" "unprognostic (7.16e-2)" "unprognostic (1.02e-1)" "unprognostic (7.66e-2)" "unprognostic (3.94e-2)" "unprognostic (3.51e-1)" "unprognostic (2.32e-1)" "unprognostic (3.06e-1)" "potential prognostic favorable (9.75e-4)" "unprognostic (9.23e-2)" "unprognostic (8.08e-2)" "unprognostic (4.02e-1)" "unprognostic (1.39e-2)" "unprognostic (1.22e-1)" IFNB1 "IFB, IFF, IFNB" ENSG00000171855 "Interferon beta 1" P01574 9 21077104-21077942 "Cancer-related genes, Predicted secreted proteins" "Antiviral defense" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 65 "pDCs: 72.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA073843 Supported "Secreted to blood" Interferon NA NA 3750 "Cluster 53: Neurons - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 1 "HPA073843: " IFNE IFNE1 ENSG00000184995 "Interferon epsilon" Q86WN2 9 21480839-21482313 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "esophagus: 1.4;urinary bladder: 1.4" "Cell type enhanced" "Detected in some" "Papillary tip epithelial cells: 2.6;Renal collecting duct intercalated cells: 1.2;Renal collecting duct principal cells: 2.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 2.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 6.1" "Adipose visceral - Mesothelial cells, Pituitary gland - Thyrotropes, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted to blood" Interferon NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 37: Neurons - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 11 "unprognostic (3.32e-1)" "unprognostic (2.86e-2)" "unprognostic (1.71e-1)" "unprognostic (2.82e-1)" "unprognostic (1.54e-2)" "unprognostic (1.46e-2)" "unprognostic (3.97e-2)" "unprognostic (5.27e-3)" IFNG ENSG00000111537 "Interferon gamma" P01579 12 68154768-68159740 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Antiviral defense, Growth regulation" Cytokine "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 10.9;lymphoid tissue: 7.0" "Group enriched" "Detected in some" 5 "NK-cells: 231.6;T-cells: 232.0" "Cell type enriched" "Detected in single" 86 "leukocyte: 37.1" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "gdT-cell: 5.5;memory CD4 T-cell: 2.4;memory CD8 T-cell: 6.6;naive CD8 T-cell: 3.7" "Lineage enriched" "Detected in single" 7 "T-cells: 6.6" "Not detected" "Not detected" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" CAB010344 Approved "Secreted to blood" Interferon NA NA "Cluster 24: Non-specific - Transcription" "Cluster 15: Bone marrow - Innate immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 11 "CAB010344: " "unprognostic (5.88e-2)" "unprognostic (2.75e-3)" "unprognostic (2.63e-3)" "unprognostic (2.89e-1)" "unprognostic (2.68e-2)" "unprognostic (2.19e-2)" "unprognostic (1.76e-1)" "unprognostic (4.17e-2)" "unprognostic (8.39e-2)" "unprognostic (2.70e-1)" IFNGR1 "CD119, IFNGR" ENSG00000027697 "Interferon gamma receptor 1" P15260 6 137197483-137219449 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "cDC: 374.8;Kupffer cells: 520.7;Microglia: 673.8;monocytes: 360.1;Neutrophils: 1082.7" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 750.0;endothelial cell: 370.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Neutrophils, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025889, HPA029213, HPA063871, CAB080493, CAB080494, CAB080495" Supported Supported "Plasma membrane" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 30: White matter - Myelination" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 24 "Plasma membrane" "CAB025889: , CAB080493: , CAB080494: , CAB080495: , HPA029213: , HPA063871: " "unprognostic (1.31e-1)" "unprognostic (2.66e-1)" "unprognostic (9.31e-2)" "unprognostic (3.35e-2)" "unprognostic (2.36e-2)" "unprognostic (8.76e-2)" "unprognostic (2.36e-1)" "unprognostic (3.26e-1)" "unprognostic (5.61e-2)" "unprognostic (8.62e-3)" "potential prognostic favorable (4.69e-4)" "unprognostic (1.87e-1)" "unprognostic (2.40e-1)" "unprognostic (1.32e-1)" "unprognostic (4.70e-2)" "unprognostic (1.54e-1)" "unprognostic (2.77e-1)" "unprognostic (1.99e-2)" "unprognostic (1.53e-1)" "unprognostic (4.12e-2)" "unprognostic (4.87e-3)" "unprognostic (4.63e-2)" "unprognostic (1.16e-2)" "unprognostic (2.54e-1)" "unprognostic (3.98e-2)" "unprognostic (1.26e-2)" "unprognostic (1.28e-1)" "unprognostic (2.15e-1)" "unprognostic (6.69e-2)" "unprognostic (1.35e-1)" "unprognostic (1.42e-1)" IFNGR2 "AF-1, IFNGT1" ENSG00000159128 "Interferon gamma receptor 2" P38484 21 33403413-33479348 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" Receptor "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglia: 174.1;monocytes: 94.4;Neutrophils: 216.8;Papillary tip epithelial cells: 81.7;Renal collecting duct intercalated cells: 86.1;Urothelial cells: 81.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 671.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001535 Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 74: Non-specific - Signal transduction" "Cluster 12: Non-specific - Vasculature" "Cluster 69: Skin cancer - ECM organization" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 28 "Nucleoplasm, Golgi apparatus" "HPA001535: " "unprognostic (5.83e-3)" "unprognostic (1.67e-1)" "unprognostic (1.58e-1)" "potential prognostic unfavorable (1.58e-4)" "unprognostic (3.51e-1)" "potential prognostic unfavorable (7.45e-4)" "unprognostic (1.92e-1)" "unprognostic (4.89e-2)" "unprognostic (1.79e-1)" "unprognostic (1.60e-1)" "potential prognostic favorable (9.15e-4)" "unprognostic (1.17e-1)" "unprognostic (2.26e-1)" "unprognostic (1.86e-3)" "unprognostic (5.83e-3)" "unprognostic (2.84e-1)" "unprognostic (1.35e-2)" "unprognostic (2.85e-3)" "unprognostic (1.54e-1)" "unprognostic (4.98e-2)" "unprognostic (2.27e-1)" "unprognostic (2.68e-1)" "unprognostic (1.35e-3)" "unprognostic (1.58e-1)" "unprognostic (5.68e-2)" "unprognostic (7.13e-2)" "unprognostic (4.23e-1)" "unprognostic (7.42e-2)" "unprognostic (3.51e-2)" "unprognostic (3.09e-2)" "unprognostic (9.13e-2)" IFNK ENSG00000147896 "Interferon kappa" Q9P0W0 9 27524290-27526498 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Cardiomyocytes: 3.2;Epicardial cells: 4.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Head and Neck Squamous Cell Carcinoma (TCGA): 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 35 "Bladder cancer: 3.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted to blood" Interferon NA NA "Cluster 11: White matter - Signal transduction" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "unprognostic (2.06e-2)" "unprognostic (4.85e-3)" "unprognostic (3.00e-1)" IFNL1 "IL-29, IL29" ENSG00000182393 "Interferon lambda 1" Q8IU54 19 39296407-39298673 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "cDC: 6.7;Innate lymphoid cells: 3.3;NK-cells: 4.8;T-cells: 2.3" "Cell type enriched" "Detected in single" 44 "leukocyte: 4.5" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 10 "gdT-cell: 2.7;MAIT T-cell: 2.8;memory CD4 T-cell: 1.3;memory CD8 T-cell: 2.7;myeloid DC: 2.3;naive CD8 T-cell: 1.4;NK-cell: 4.6" "Group enriched" "Detected in many" 33 "dendritic cells: 2.3;NK-cells: 4.6;T-cells: 2.8" "Not detected" "Not detected" "Secreted to blood" Interferon NA NA 97000 "Cluster 1: T-cells - Unknown function" "Cluster 51: Neurons - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 1 IFNL2 "IL-28A, IL28A" ENSG00000183709 "Interferon lambda 2" Q8IZJ0 19 39268396-39270188 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Epicardial cells: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" CAB025489 Uncertain "Secreted to blood" Interferon NA NA "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" "CAB025489: " IFNL3 "IL-28B, IL28B, IL28C" ENSG00000197110 "Interferon lambda 3" Q8IZI9 19 39243455-39245250 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" Interferon NA NA 1700 "Cluster 31: Non-specific - Antiviral immune response" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" IFNL4 IFNAN ENSG00000272395 "Interferon lambda 4 (gene/pseudogene)" 19 39246314-39248856 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Early spermatids: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted - unknown location" NA NA "Cluster 1: Neurons - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" IFNLR1 "CRF2/12, IFNLR, IL-28R1, IL28RA" ENSG00000185436 "Interferon lambda receptor 1" Q8IU57 1 24154168-24187959 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Antiviral defense" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Enterocytes: 101.8;Epididymal basal cells: 64.7;Epididymal efferent duct absorptive cells: 72.6;Epididymal efferent duct ciliated cells: 91.5;Ocular epithelial cells: 113.5;pDCs: 110.4;Thyrotrophs: 64.7;Urothelial cells: 102.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 4.9;naive B-cell: 5.9;plasmacytoid DC: 11.4" "Group enriched" "Detected in many" 5 "B-cells: 5.9;dendritic cells: 11.4" "Cancer enhanced" "Detected in many" "lymphoma: 20.0" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Skin - Keratinocyte (other), Spleen - B-cells (Spleen), Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA017319 Uncertain Approved Cytosol "Intracellular and membrane" Receptor NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 25: Non-specific - Transcription" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 100: Stratified epithelial cells - Barrier functions" 4 Cytosol "HPA017319: " "unprognostic (1.40e-1)" "potential prognostic favorable (3.03e-4)" "unprognostic (2.32e-2)" "unprognostic (1.05e-1)" "unprognostic (5.40e-2)" "unprognostic (1.70e-1)" "unprognostic (5.18e-2)" "unprognostic (5.49e-2)" "unprognostic (1.35e-2)" "validated prognostic favorable (2.25e-5)" "validated prognostic favorable (7.31e-5)" "unprognostic (7.01e-2)" "unprognostic (1.21e-2)" "unprognostic (4.77e-2)" "unprognostic (1.56e-1)" "unprognostic (3.06e-1)" "unprognostic (2.32e-2)" "unprognostic (2.03e-1)" "unprognostic (3.71e-1)" "unprognostic (5.23e-2)" "unprognostic (4.06e-3)" "unprognostic (8.31e-2)" "unprognostic (8.88e-2)" "unprognostic (6.28e-3)" "unprognostic (2.12e-2)" "unprognostic (2.19e-2)" "unprognostic (2.76e-1)" "unprognostic (3.33e-1)" "unprognostic (9.74e-2)" IFNW1 ENSG00000177047 "Interferon omega 1" P05000 9 21140632-21141832 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" Interferon NA NA "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 55: Lymphoma - Immune response" 3 "unprognostic (1.27e-1)" IFRD1 "PC4, TIS7" ENSG00000006652 "Interferon related developmental regulator 1" O00458 7 112422887-112481017 "Predicted intracellular proteins, Predicted membrane proteins" Differentiation "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 54.0" "Cell type enhanced" "Detected in many" "Astrocytes: 82.0;Bergmann glia: 57.0;Brain excitatory neurons: 49.4;Choroid plexus epithelial cells: 100.0;Distal convoluted tubule cells: 65.3;Early spermatids: 108.6;Ependymal cells: 66.9;Loop of henle epithelial cells: 72.6;Microglia: 83.4;Neutrophils: 51.0;Oligodendrocytes: 49.9;Other brain neurons: 45.0;Podocytes: 49.6;Proximal tubule cells: 59.1;Renal collecting duct intercalated cells: 71.8;Renal collecting duct principal cells: 45.5;Renal connecting tubule cells: 77.4;Sertoli cells: 52.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "eosinophil: 64.3;neutrophil: 112.7" "Lineage enriched" "Detected in all" 13 "granulocytes: 112.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024122, HPA072413" Enhanced Approved "Endoplasmic reticulum,Plasma membrane,Cytosol" No No "Cluster 21: Neutrophils - Unknown function" "Cluster 8: Pancreas - Proteolysis" "Cluster 12: Non-specific - Vasculature" "Cluster 7: Liver cancer - Metabolism" "Cluster 102: Non-specific - Mixed function" 2 "Plasma membrane" "Endoplasmic reticulum, Cytosol" "HPA024122: , HPA072413: " "unprognostic (1.22e-1)" "unprognostic (7.50e-2)" "unprognostic (5.63e-2)" "unprognostic (4.92e-2)" "unprognostic (1.09e-1)" "unprognostic (1.24e-1)" "unprognostic (9.35e-2)" "unprognostic (1.53e-2)" "unprognostic (1.89e-1)" "potential prognostic unfavorable (1.43e-4)" "unprognostic (5.36e-3)" "unprognostic (5.55e-2)" "unprognostic (4.92e-2)" "potential prognostic unfavorable (2.78e-4)" "unprognostic (2.47e-2)" "unprognostic (4.07e-2)" "unprognostic (1.04e-1)" "unprognostic (2.42e-1)" "unprognostic (3.42e-1)" "unprognostic (6.46e-2)" "unprognostic (1.28e-1)" "unprognostic (1.78e-1)" "potential prognostic unfavorable (6.73e-5)" "unprognostic (4.18e-2)" "unprognostic (2.60e-2)" "unprognostic (4.56e-2)" "unprognostic (1.95e-2)" "unprognostic (1.82e-1)" "unprognostic (8.00e-2)" "unprognostic (6.25e-2)" "unprognostic (1.35e-1)" IFRD2 "IFNRP, SKMc15, SM15" ENSG00000214706 "Interferon related developmental regulator 2" Q12894 3 50287732-50292918 "Predicted intracellular proteins, Predicted membrane proteins" "Translation regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 113.2;Late spermatids: 184.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068560 Approved Approved Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 70: Non-specific - Protein processing" "Cluster 27: Non-specific - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 17: Non-specific - RNA processing" 9 Nucleoplasm "HPA068560: " "unprognostic (1.17e-1)" "unprognostic (5.28e-3)" "unprognostic (4.66e-3)" "unprognostic (8.82e-2)" "unprognostic (3.21e-2)" "unprognostic (1.55e-1)" "unprognostic (2.79e-1)" "unprognostic (3.86e-1)" "unprognostic (7.91e-2)" "unprognostic (3.67e-1)" "potential prognostic unfavorable (6.32e-4)" "unprognostic (4.24e-2)" "unprognostic (7.03e-2)" "unprognostic (9.67e-3)" "unprognostic (2.23e-3)" "unprognostic (2.91e-2)" "potential prognostic unfavorable (1.34e-4)" "unprognostic (8.37e-2)" "unprognostic (2.26e-2)" "unprognostic (1.22e-1)" "unprognostic (3.79e-2)" "unprognostic (1.08e-2)" "unprognostic (2.76e-1)" "unprognostic (2.06e-1)" "unprognostic (1.69e-1)" "unprognostic (1.41e-1)" "unprognostic (1.68e-2)" "unprognostic (3.59e-2)" "unprognostic (1.14e-1)" "unprognostic (1.15e-1)" "unprognostic (5.36e-2)" IFT122 "FAP80, SPG, WDR10, WDR10p, WDR140" ENSG00000163913 "Intraflagellar transport 122" Q9HBG6 3 129429607-129520510 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Cilium biogenesis/degradation" "Developmental protein" "Ciliopathy, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 44.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 275.9;Early primary spermatocytes: 212.7;Early spermatids: 175.7;Ependymal cells: 152.2;Late primary spermatocytes: 164.0;Late spermatids: 231.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041815 Uncertain Approved "Primary cilium transition zone,Cytosol,Mid piece,Principal piece" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" 25 "Primary cilium transition zone, Cytosol, Mid piece" "Principal piece" "HPA041815: " "unprognostic (2.08e-1)" "unprognostic (6.84e-2)" "unprognostic (6.23e-2)" "unprognostic (5.79e-2)" "unprognostic (2.11e-1)" "unprognostic (2.52e-1)" "unprognostic (4.49e-1)" "unprognostic (1.62e-1)" "unprognostic (2.25e-2)" "unprognostic (1.25e-1)" "validated prognostic favorable (2.53e-7)" "validated prognostic favorable (6.15e-4)" "unprognostic (8.78e-2)" "unprognostic (7.21e-2)" "unprognostic (1.68e-1)" "unprognostic (8.45e-2)" "unprognostic (4.39e-3)" "unprognostic (1.65e-1)" "unprognostic (4.33e-1)" "unprognostic (1.68e-1)" "unprognostic (7.82e-2)" "unprognostic (1.76e-1)" "unprognostic (4.59e-2)" "unprognostic (6.95e-2)" "unprognostic (1.44e-2)" "unprognostic (2.79e-1)" "unprognostic (5.44e-2)" "unprognostic (1.95e-1)" "unprognostic (2.77e-1)" "unprognostic (7.47e-2)" "unprognostic (1.42e-1)" IFT140 "gs114, KIAA0590, WDTC2" ENSG00000187535 "Intraflagellar transport 140" Q96RY7 16 1510427-1612072 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 97.3;Respiratory ciliated cells: 144.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 3.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042197 Approved Supported "Nucleoplasm,Mitochondria,Basal body" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 21: Testis - Mixed function" "Cluster 17: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 32 "Basal body" "Nucleoplasm, Mitochondria" "HPA042197: " "unprognostic (6.04e-2)" "unprognostic (1.07e-1)" "unprognostic (5.19e-2)" "unprognostic (2.13e-2)" "unprognostic (5.52e-2)" "unprognostic (8.85e-2)" "unprognostic (3.90e-1)" "unprognostic (2.91e-3)" "unprognostic (3.44e-2)" "unprognostic (3.05e-1)" "unprognostic (5.93e-3)" "unprognostic (9.88e-2)" "unprognostic (4.04e-3)" "unprognostic (3.20e-2)" "unprognostic (3.72e-2)" "unprognostic (4.00e-3)" "unprognostic (4.30e-1)" "unprognostic (2.78e-3)" "unprognostic (6.73e-3)" "unprognostic (2.47e-2)" "unprognostic (3.68e-2)" "unprognostic (2.11e-1)" "unprognostic (2.00e-1)" "unprognostic (1.38e-2)" "unprognostic (2.00e-3)" "unprognostic (3.50e-1)" "unprognostic (3.20e-2)" "unprognostic (9.36e-2)" "unprognostic (9.79e-2)" "unprognostic (1.20e-3)" "potential prognostic favorable (1.72e-4)" IFT172 "BBS20, NPHP17, osm-1, SLB, wim" ENSG00000138002 "Intraflagellar transport 172" Q9UG01 2 27444377-27489805 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Obesity, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 659.7;Late spermatids: 924.8;Respiratory ciliated cells: 290.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Spleen - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044893 Uncertain NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 46 "HPA044893: " "unprognostic (2.67e-2)" "unprognostic (2.51e-1)" "unprognostic (1.49e-2)" "unprognostic (4.98e-1)" "unprognostic (2.28e-1)" "unprognostic (2.17e-1)" "unprognostic (2.38e-1)" "unprognostic (3.19e-1)" "unprognostic (6.59e-2)" "unprognostic (2.12e-2)" "validated prognostic favorable (8.02e-9)" "validated prognostic favorable (5.03e-4)" "unprognostic (3.28e-2)" "unprognostic (1.11e-2)" "unprognostic (5.85e-2)" "unprognostic (1.09e-2)" "unprognostic (2.24e-1)" "unprognostic (3.20e-1)" "unprognostic (9.78e-2)" "unprognostic (7.39e-2)" "unprognostic (1.20e-2)" "unprognostic (3.75e-2)" "unprognostic (1.48e-2)" "unprognostic (3.74e-1)" "unprognostic (9.25e-3)" "unprognostic (8.90e-2)" "unprognostic (1.48e-2)" "unprognostic (2.19e-1)" "unprognostic (1.87e-1)" "unprognostic (2.02e-1)" "unprognostic (5.75e-2)" IFT20 ENSG00000109083 "Intraflagellar transport 20" Q8IY31 17 28328325-28335489 "Predicted intracellular proteins" "Cilium biogenesis/degradation, Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 212.5;Early spermatids: 254.5;Late primary spermatocytes: 245.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021376 Approved Approved "Microtubules,Mitotic spindle,Primary cilium,Basal body,Flagellar centriole,Mid piece,Principal piece,End piece" Yes NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 8: Pancreas - Proteolysis" "Cluster 21: Non-specific - Metabolism" "Cluster 27: Breast cancer - Unknown function" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 73 "Microtubules, Primary cilium" "Mitotic spindle, Basal body, Flagellar centriole, Mid piece, Principal piece, End piece" "HPA021376: " "unprognostic (8.31e-2)" "unprognostic (1.17e-1)" "unprognostic (3.52e-1)" "unprognostic (1.72e-2)" "unprognostic (1.13e-1)" "unprognostic (2.30e-2)" "unprognostic (3.64e-3)" "unprognostic (1.11e-1)" "unprognostic (5.92e-3)" "unprognostic (4.53e-2)" "unprognostic (1.88e-3)" "unprognostic (9.09e-2)" "unprognostic (2.89e-1)" "validated prognostic unfavorable (8.10e-5)" "validated prognostic unfavorable (2.36e-4)" "unprognostic (2.48e-1)" "unprognostic (7.82e-2)" "unprognostic (5.03e-2)" "unprognostic (1.48e-1)" "unprognostic (2.28e-1)" "unprognostic (5.16e-2)" "unprognostic (3.09e-3)" "unprognostic (4.46e-2)" "unprognostic (1.63e-2)" "unprognostic (4.64e-2)" "unprognostic (1.45e-1)" "unprognostic (3.32e-3)" "unprognostic (7.14e-3)" "unprognostic (6.85e-2)" "unprognostic (4.65e-2)" "unprognostic (2.01e-2)" IFT22 "DKFZp761N0823, FAP9, FLJ13225, FLJ14117, RABL5" ENSG00000128581 "Intraflagellar transport 22" Q9H7X7 7 101310914-101321823 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 69.9" "Cell type enhanced" "Detected in many" "Early spermatids: 521.4;Epididymal efferent duct ciliated cells: 293.0;Fallopian tube ciliated cells: 310.8;Late primary spermatocytes: 776.8;Late spermatids: 2180.3;Respiratory ciliated cells: 286.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042930 Approved Approved "Microtubules,Mitotic spindle,Primary cilium,Basal body,Cytosol,Flagellar centriole,Mid piece,Principal piece,End piece" Yes NA "Cluster 24: Non-specific - Transcription" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 56 "Microtubules, Cytosol" "Mitotic spindle, Primary cilium, Basal body, Flagellar centriole, Mid piece, Principal piece, End piece" "HPA042930: " "unprognostic (1.15e-1)" "unprognostic (2.27e-1)" "unprognostic (1.52e-1)" "unprognostic (2.77e-2)" "unprognostic (1.75e-1)" "unprognostic (1.52e-2)" "potential prognostic unfavorable (6.35e-5)" "unprognostic (4.28e-2)" "unprognostic (2.56e-2)" "unprognostic (1.68e-1)" "unprognostic (7.40e-2)" "unprognostic (7.38e-3)" "unprognostic (2.80e-3)" "unprognostic (1.92e-1)" "unprognostic (1.66e-2)" "unprognostic (1.68e-1)" "unprognostic (1.62e-1)" "unprognostic (1.48e-1)" "unprognostic (3.83e-1)" "unprognostic (2.14e-1)" "unprognostic (2.51e-1)" "unprognostic (1.46e-3)" "unprognostic (9.95e-2)" "unprognostic (2.00e-1)" "unprognostic (2.12e-2)" "unprognostic (7.32e-2)" "unprognostic (3.37e-2)" "unprognostic (3.62e-1)" "unprognostic (2.75e-3)" IFT27 "BBS19, FAP156, RABL4, RAYL" ENSG00000100360 "Intraflagellar transport 27" Q9BW83 22 36758202-36776256 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Differentiation, Protein transport, Spermatogenesis, Transport" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ependymal cells: 127.1;Epididymal efferent duct ciliated cells: 316.5;Fallopian tube ciliated cells: 278.1;Late primary spermatocytes: 137.9;Respiratory ciliated cells: 306.2" "Cell type enhanced" "Detected in all" "ependymal cell: 141.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Pituitary gland - Lactotropes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048791 Uncertain NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 27: Breast cancer - Unknown function" "Cluster 107: Ciliated cells - Cilia assembly & function" 45 "HPA048791: " "unprognostic (1.87e-1)" "unprognostic (2.54e-1)" "unprognostic (1.47e-2)" "unprognostic (3.30e-2)" "unprognostic (3.66e-1)" "unprognostic (2.14e-1)" "unprognostic (1.15e-1)" "unprognostic (2.89e-2)" "unprognostic (5.71e-2)" "unprognostic (3.88e-2)" "unprognostic (2.46e-3)" "unprognostic (7.50e-2)" "potential prognostic favorable (2.70e-4)" "unprognostic (2.14e-2)" "unprognostic (2.27e-2)" "unprognostic (1.38e-3)" "unprognostic (1.03e-1)" "unprognostic (8.43e-2)" "unprognostic (2.42e-3)" "unprognostic (9.54e-3)" "unprognostic (4.22e-2)" "unprognostic (2.18e-2)" "unprognostic (9.25e-2)" "unprognostic (1.55e-1)" "unprognostic (3.46e-2)" "unprognostic (2.72e-1)" "unprognostic (1.36e-1)" "unprognostic (4.93e-2)" "unprognostic (1.89e-1)" "unprognostic (5.04e-2)" "unprognostic (3.26e-2)" IFT43 "C14orf179, FLJ32173, MGC16028" ENSG00000119650 "Intraflagellar transport 43" Q96FT9 14 75902136-76084585 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Ectodermal dysplasia, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Fallopian tube ciliated cells: 383.0;Respiratory ciliated cells: 366.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003438 Approved Supported "Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Centriolar satellite,Basal body,Perinuclear theca,Principal piece,End piece" Yes NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 107: Ciliated cells - Cilia assembly & function" 27 "Microtubules, Primary cilium, Principal piece, End piece" "Cytokinetic bridge, Mitotic spindle, Centriolar satellite, Basal body, Perinuclear theca" "HPA003438: " "unprognostic (2.40e-2)" "unprognostic (3.45e-2)" "potential prognostic favorable (7.64e-4)" "unprognostic (7.14e-2)" "unprognostic (3.95e-2)" "unprognostic (7.25e-2)" "unprognostic (2.13e-1)" "unprognostic (2.56e-2)" "unprognostic (1.31e-3)" "unprognostic (2.43e-2)" "unprognostic (2.83e-1)" "unprognostic (3.52e-3)" "unprognostic (4.27e-3)" "unprognostic (8.21e-3)" "unprognostic (1.44e-1)" "unprognostic (9.22e-2)" "unprognostic (9.15e-2)" "unprognostic (3.26e-1)" "unprognostic (1.17e-1)" "unprognostic (2.03e-1)" "unprognostic (4.80e-2)" "unprognostic (7.82e-2)" "unprognostic (3.53e-1)" "unprognostic (6.32e-2)" "unprognostic (2.26e-1)" "unprognostic (1.55e-1)" "unprognostic (5.41e-2)" "unprognostic (5.79e-2)" "unprognostic (1.85e-1)" "unprognostic (4.58e-2)" IFT46 "C11orf2, C11orf60, CFAP32, FLJ21827" ENSG00000118096 "Intraflagellar transport 46" Q9NQC8 11 118544528-118572970 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 80.5;Endometrial ciliated cells: 87.5;Ependymal cells: 92.8;Epididymal efferent duct ciliated cells: 122.6;Fallopian tube ciliated cells: 170.8;Respiratory ciliated cells: 115.9" "Cell type enriched" "Detected in all" 4 "ependymal cell: 113.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Lung - Respiratory ciliated cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037909, HPA057550" Approved Approved "Actin filaments,Primary cilium,Principal piece" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 24: Non-specific - Unknown function" "Cluster 107: Ciliated cells - Cilia assembly & function" 48 "Actin filaments, Primary cilium, Principal piece" "HPA037909: , HPA057550: " "unprognostic (5.83e-3)" "unprognostic (1.39e-1)" "unprognostic (1.27e-1)" "unprognostic (2.10e-1)" "unprognostic (4.11e-1)" "unprognostic (5.52e-2)" "unprognostic (2.34e-1)" "unprognostic (4.10e-2)" "unprognostic (7.43e-2)" "unprognostic (2.19e-2)" "potential prognostic favorable (1.20e-6)" "unprognostic (1.12e-2)" "potential prognostic favorable (1.17e-7)" "unprognostic (1.99e-1)" "potential prognostic favorable (7.96e-4)" "unprognostic (5.34e-2)" "unprognostic (2.56e-2)" "unprognostic (2.85e-2)" "unprognostic (1.44e-1)" "unprognostic (8.80e-2)" "unprognostic (1.67e-1)" "unprognostic (4.81e-2)" "unprognostic (3.29e-2)" "unprognostic (3.53e-2)" "unprognostic (4.87e-2)" "unprognostic (1.22e-1)" "potential prognostic unfavorable (4.67e-4)" "unprognostic (1.05e-1)" "unprognostic (2.53e-1)" "unprognostic (2.03e-1)" "unprognostic (3.67e-3)" IFT52 "C20orf9, CGI-53, dJ1028D15.1, NGD2, NGD5" ENSG00000101052 "Intraflagellar transport 52" Q9Y366 20 43590937-43647299 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Prostate - Fibroblasts, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063367, HPA067423" Enhanced Approved "Microtubules,Primary cilium,Basal body,Cytosol" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 62: Non-specific - Plasma proteins" "Cluster 107: Ciliated cells - Cilia assembly & function" 37 Microtubules "Primary cilium, Basal body, Cytosol" "HPA063367: , HPA067423: " "unprognostic (3.92e-2)" "unprognostic (1.20e-2)" "unprognostic (3.03e-1)" "unprognostic (4.48e-2)" "unprognostic (3.32e-1)" "unprognostic (5.27e-2)" "unprognostic (1.10e-1)" "unprognostic (5.51e-2)" "unprognostic (1.11e-1)" "unprognostic (2.95e-3)" "potential prognostic favorable (7.61e-6)" "unprognostic (2.22e-1)" "unprognostic (8.72e-2)" "potential prognostic unfavorable (5.11e-5)" "unprognostic (1.60e-2)" "unprognostic (6.16e-2)" "unprognostic (5.18e-2)" "unprognostic (1.96e-1)" "unprognostic (3.26e-1)" "unprognostic (2.32e-1)" "unprognostic (4.67e-3)" "unprognostic (6.47e-2)" "unprognostic (9.32e-2)" "unprognostic (1.05e-1)" "unprognostic (4.17e-2)" "unprognostic (5.54e-3)" "unprognostic (1.32e-1)" "unprognostic (1.29e-1)" "unprognostic (9.38e-2)" "unprognostic (4.97e-2)" "unprognostic (2.41e-1)" IFT57 "ESRRBL1, FLJ10147, HIPPI, MHS4R2" ENSG00000114446 "Intraflagellar transport 57" Q9NWB7 3 108160812-108222435 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" DNA-binding Ciliopathy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 1871.3;Epididymal efferent duct ciliated cells: 472.6;Fallopian tube ciliated cells: 599.9;Late primary spermatocytes: 901.9;Late spermatids: 3984.0;Respiratory ciliated cells: 798.6;Transitional alveolar cells: 526.5" "Cell type enhanced" "Detected in all" "ependymal cell: 155.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 42.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035514, HPA035515" Supported Approved "Golgi apparatus,Primary cilium,Primary cilium transition zone,Centriolar satellite,Basal body,Cytosol,Mid piece" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 22: Epididymis - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 68 "Golgi apparatus, Primary cilium, Basal body, Mid piece" "Primary cilium transition zone, Centriolar satellite, Cytosol" "HPA035514: , HPA035515: " "unprognostic (1.45e-1)" "unprognostic (4.99e-2)" "unprognostic (9.08e-2)" "unprognostic (4.94e-2)" "unprognostic (6.45e-2)" "unprognostic (2.96e-3)" "unprognostic (3.02e-2)" "unprognostic (2.07e-2)" "unprognostic (2.96e-2)" "unprognostic (5.29e-2)" "potential prognostic favorable (1.88e-4)" "unprognostic (6.14e-2)" "unprognostic (5.89e-2)" "unprognostic (2.21e-2)" "unprognostic (1.91e-2)" "unprognostic (3.98e-2)" "unprognostic (1.56e-1)" "unprognostic (1.50e-2)" "unprognostic (1.05e-1)" "unprognostic (2.14e-2)" "unprognostic (1.47e-2)" "unprognostic (6.75e-2)" "unprognostic (2.60e-1)" "unprognostic (4.99e-1)" "unprognostic (4.28e-2)" "unprognostic (3.02e-1)" "unprognostic (3.63e-2)" "unprognostic (1.38e-1)" "unprognostic (1.50e-1)" "unprognostic (7.87e-2)" "unprognostic (2.03e-2)" IFT74 "CCDC2, CMG-1, CMG1, FLJ22621" ENSG00000096872 "Intraflagellar transport 74" Q96LB3 9 26947039-27066134 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Cilium biogenesis/degradation" "Developmental protein" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Joubert syndrome, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 425.8;Respiratory ciliated cells: 242.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020247, HPA026684" Approved Supported "Golgi apparatus,Centriolar satellite,Basal body,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 22: Epididymis - Mixed function" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 50 "Golgi apparatus, Centriolar satellite, Basal body" Cytosol "HPA020247: , HPA026684: " "unprognostic (7.75e-3)" "unprognostic (6.21e-2)" "unprognostic (4.41e-1)" "unprognostic (7.09e-2)" "unprognostic (2.79e-1)" "unprognostic (1.89e-1)" "unprognostic (1.11e-1)" "unprognostic (7.40e-2)" "unprognostic (1.49e-2)" "unprognostic (1.60e-1)" "unprognostic (5.18e-2)" "unprognostic (2.81e-1)" "unprognostic (2.50e-1)" "unprognostic (4.13e-3)" "unprognostic (3.61e-2)" "unprognostic (4.30e-1)" "unprognostic (5.95e-2)" "unprognostic (1.38e-1)" "unprognostic (2.41e-1)" "unprognostic (3.90e-2)" "unprognostic (2.37e-1)" "unprognostic (1.63e-1)" "unprognostic (8.96e-3)" "unprognostic (1.46e-1)" "unprognostic (1.65e-3)" "unprognostic (1.78e-1)" "unprognostic (5.84e-2)" "unprognostic (4.26e-2)" "unprognostic (3.32e-1)" "unprognostic (6.17e-2)" "unprognostic (1.36e-1)" IFT80 "FAP167, KIAA1374, WDR56" ENSG00000068885 "Intraflagellar transport 80" Q9P2H3 3 160256986-160399880 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 62.0;Bergmann glia: 68.2;Brain excitatory neurons: 60.6;Brain inhibitory neurons: 54.7;Choroid plexus epithelial cells: 184.2;Ependymal cells: 214.3;Microglia: 43.9;Oligodendrocyte progenitor cells: 64.3;Oligodendrocytes: 238.6;Other brain neurons: 47.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035868 Uncertain NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 65: Brain - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 63: Non-specific - Protein processing" "Cluster 80: Oligodendrocytes - Myelination" 44 "HPA035868: " "unprognostic (4.32e-1)" "unprognostic (3.21e-2)" "unprognostic (2.40e-1)" "unprognostic (7.16e-2)" "unprognostic (6.19e-2)" "unprognostic (3.12e-3)" "unprognostic (4.19e-1)" "unprognostic (1.50e-1)" "unprognostic (7.70e-2)" "unprognostic (2.86e-3)" "unprognostic (1.25e-1)" "unprognostic (8.06e-2)" "unprognostic (5.84e-2)" "unprognostic (2.95e-3)" "unprognostic (8.68e-2)" "unprognostic (1.05e-1)" "unprognostic (2.37e-1)" "unprognostic (2.64e-1)" "unprognostic (1.15e-1)" "unprognostic (2.73e-1)" "unprognostic (5.75e-2)" "unprognostic (5.47e-2)" "unprognostic (6.21e-2)" "unprognostic (9.60e-3)" "unprognostic (1.18e-1)" "unprognostic (1.44e-1)" "unprognostic (1.95e-2)" "unprognostic (1.11e-1)" "unprognostic (2.54e-1)" "unprognostic (1.70e-1)" "unprognostic (1.51e-1)" IFT81 "CDV-1R, CDV1, MGC4027" ENSG00000122970 "Intraflagellar transport 81" Q8WYA0 12 110124335-110218793 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Cilium biogenesis/degradation, Differentiation, Spermatogenesis" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 184.2;Early primary spermatocytes: 243.9;Ependymal cells: 194.2;Fallopian tube ciliated cells: 218.9;Respiratory ciliated cells: 287.7" "Cell type enhanced" "Detected in all" "ependymal cell: 215.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019087, HPA020051" Enhanced Approved "Primary cilium,Centrosome,Basal body,Cytosol" NA NA "Cluster 21: Testis - Mixed function" "Cluster 17: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" 45 Cytosol "Primary cilium, Centrosome, Basal body" "HPA019087: , HPA020051: " "unprognostic (7.85e-2)" "unprognostic (3.80e-1)" "unprognostic (1.42e-1)" "unprognostic (7.95e-3)" "unprognostic (1.12e-1)" "unprognostic (7.45e-2)" "unprognostic (1.33e-1)" "unprognostic (1.58e-1)" "unprognostic (3.00e-2)" "unprognostic (5.72e-3)" "unprognostic (4.25e-2)" "unprognostic (9.13e-2)" "unprognostic (7.60e-2)" "unprognostic (8.19e-2)" "unprognostic (1.91e-1)" "unprognostic (2.52e-1)" "unprognostic (3.05e-1)" "unprognostic (2.07e-1)" "unprognostic (5.49e-2)" "unprognostic (7.19e-2)" "unprognostic (1.31e-1)" "unprognostic (2.88e-2)" "unprognostic (3.28e-2)" "unprognostic (2.80e-2)" "unprognostic (3.35e-2)" "unprognostic (5.94e-3)" "unprognostic (2.15e-1)" "unprognostic (1.35e-2)" "unprognostic (2.86e-1)" "unprognostic (6.04e-2)" "unprognostic (3.10e-1)" IFT88 "D13S1056E, hTg737, MGC26259, Tg737, TTC10" ENSG00000032742 "Intraflagellar transport 88" Q13099 13 20567138-20691444 "Predicted intracellular proteins, Transporters" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 65.5" "Cell type enhanced" "Detected in all" "Early primary spermatocytes: 375.3;Ependymal cells: 505.2;Late primary spermatocytes: 332.7;Respiratory ciliated cells: 454.2;Rod photoreceptor cells: 390.2" "Cell type enhanced" "Detected in all" "ependymal cell: 558.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Spleen - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078625 Approved "Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Centriolar satellite,Basal body,Connecting piece,Mid piece,Principal piece,End piece" Yes NA "Cluster 14: Non-specific - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 34: Ciliated cells - Cilia assembly & function" 49 "Microtubules, Primary cilium, End piece" "Cytokinetic bridge, Mitotic spindle, Centriolar satellite, Basal body, Connecting piece, Mid piece, Principal piece" "HPA078625: " "unprognostic (2.14e-1)" "unprognostic (2.57e-1)" "unprognostic (9.64e-2)" "unprognostic (3.20e-2)" "unprognostic (2.32e-1)" "unprognostic (4.87e-2)" "unprognostic (1.33e-1)" "unprognostic (2.92e-1)" "unprognostic (4.58e-1)" "unprognostic (1.80e-3)" "validated prognostic favorable (2.29e-9)" "validated prognostic favorable (3.10e-4)" "unprognostic (8.55e-3)" "unprognostic (1.45e-1)" "unprognostic (2.19e-2)" "unprognostic (1.64e-1)" "unprognostic (1.10e-1)" "unprognostic (3.94e-2)" "unprognostic (1.41e-1)" "unprognostic (1.29e-1)" "unprognostic (1.12e-1)" "unprognostic (8.96e-3)" "unprognostic (5.54e-3)" "unprognostic (2.44e-1)" "unprognostic (2.58e-2)" "unprognostic (3.67e-1)" "unprognostic (2.44e-2)" "unprognostic (1.46e-1)" "unprognostic (9.63e-2)" "unprognostic (1.89e-1)" "unprognostic (6.09e-2)" IFTAP "C11orf74, FLJ38678, HEPIS, NWC" ENSG00000166352 "Intraflagellar transport associated protein" Q86VG3 11 36594369-36675695 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 255.0;Early spermatids: 162.4;Epididymal efferent duct ciliated cells: 160.7;Fallopian tube ciliated cells: 184.6;Late primary spermatocytes: 332.3;Late spermatids: 242.6;Respiratory ciliated cells: 186.4" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 197.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044880 Uncertain Approved Aggresome,Cytosol NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 3 Cytosol Aggresome "HPA044880: " "unprognostic (2.81e-1)" "unprognostic (2.62e-2)" "unprognostic (2.09e-1)" "unprognostic (7.92e-2)" "unprognostic (8.74e-3)" "unprognostic (1.25e-2)" "unprognostic (1.02e-1)" "unprognostic (1.75e-3)" "potential prognostic unfavorable (2.98e-5)" "unprognostic (1.92e-2)" "unprognostic (2.90e-1)" "unprognostic (2.04e-1)" "unprognostic (2.35e-3)" "unprognostic (2.94e-3)" "unprognostic (1.92e-2)" "unprognostic (9.21e-2)" "unprognostic (2.59e-1)" "unprognostic (1.05e-1)" "unprognostic (3.46e-2)" "unprognostic (5.56e-3)" "unprognostic (2.06e-2)" "unprognostic (3.63e-1)" "unprognostic (5.01e-2)" "unprognostic (1.72e-1)" "unprognostic (9.24e-2)" "unprognostic (2.07e-3)" "unprognostic (4.82e-2)" "unprognostic (9.99e-2)" "unprognostic (7.98e-2)" IGBP1 "alpha4, IBP1" ENSG00000089289 "Immunoglobulin binding protein 1" P78318 X 70133447-70166324 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "B-cell activation" Chaperone "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Enterocytes: 341.3;Esophageal apical cells: 337.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000634, HPA001004, CAB034139" Approved Approved "Microtubules,Cytokinetic bridge,Primary cilium,Basal body" Yes NA 34000 "Cluster 31: T-cells - T-cell receptor" "Cluster 54: Non-specific - Ribosome" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 47 "Microtubules, Primary cilium" "Cytokinetic bridge, Basal body" "CAB034139: , HPA000634: , HPA001004: " "unprognostic (1.23e-1)" "unprognostic (2.75e-1)" "unprognostic (5.27e-1)" "unprognostic (9.20e-3)" "unprognostic (4.48e-1)" "unprognostic (2.90e-1)" "unprognostic (2.02e-3)" "unprognostic (5.46e-2)" "unprognostic (8.29e-3)" "unprognostic (3.79e-1)" "validated prognostic favorable (3.38e-10)" "validated prognostic favorable (6.10e-4)" "unprognostic (5.63e-2)" "unprognostic (3.75e-3)" "potential prognostic unfavorable (7.16e-5)" "unprognostic (5.66e-1)" "potential prognostic unfavorable (6.20e-4)" "unprognostic (2.24e-2)" "unprognostic (2.07e-2)" "unprognostic (2.02e-1)" "unprognostic (1.07e-1)" "unprognostic (9.06e-2)" "unprognostic (3.09e-1)" "unprognostic (3.05e-1)" "unprognostic (3.54e-2)" "unprognostic (1.54e-1)" "unprognostic (2.05e-1)" "unprognostic (1.48e-1)" "unprognostic (6.12e-2)" "unprognostic (8.45e-3)" "unprognostic (3.88e-2)" IGBP1P2 ENSG00000266826 "Immunoglobulin (CD79A) binding protein 1 pseudogene 2" 17 58660424-58692045 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Tissue enriched" "Detected in single" 32 "testis: 8.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "HPA000634, HPA001004" Uncertain Approved "Microtubules,Cytokinetic bridge,Primary cilium,Basal body" Yes NA "Cluster 6: Testis - Spermatogenesis" "Cluster 61: BICR 18 - Protein kinases" "Microtubules, Primary cilium" "Cytokinetic bridge, Basal body" "HPA000634: , HPA001004: " IGDCC3 "HsT18880, PUNC" ENSG00000174498 "Immunoglobulin superfamily DCC subclass member 3" Q8IVU1 15 65327127-65378002 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.3;parathyroid gland: 4.8;placenta: 5.7" "Cell type enhanced" "Detected in many" "Astrocytes: 39.7;Cone photoreceptor cells: 37.3;Cytotrophoblasts: 156.4;Early spermatids: 51.0;Late spermatids: 139.3;Migrating cytotrophoblasts: 39.3;Oligodendrocyte progenitor cells: 29.4;Oocytes: 32.2;Pituitary stem cells: 25.7;Syncytiotrophoblasts: 40.7" "Cell type enhanced" "Detected in many" "astrocyte: 53.2" "Group enriched" "Detected in some" 5 "Glioblastoma Multiforme (TCGA): 4.8;Testicular Germ Cell Tumor (TCGA): 10.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 9.6;testis cancer: 38.6" "Breast - Breast glandular cells, Colon - Enteric glia cells, Stomach - Gastric enteroendocrine cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA015713 Uncertain Nucleoplasm,Vesicles NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 15: Non-specific - Transcription" "Cluster 18: Liver cancer - Metabolism" "Cluster 63: Cytotrophoblasts - Basic cellular functions" "Nucleoplasm, Vesicles" "HPA015713: " "unprognostic (7.79e-3)" "unprognostic (2.34e-1)" "unprognostic (4.77e-2)" "unprognostic (1.04e-1)" "unprognostic (3.23e-3)" "unprognostic (3.90e-1)" "unprognostic (3.61e-1)" "unprognostic (2.72e-1)" IGDCC4 "LOC57722, NOPE" ENSG00000103742 "Immunoglobulin superfamily DCC subclass member 4" Q8TDY8 15 65381484-65422947 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 9.9;tongue: 13.1" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 50.8;Astrocytes: 38.1;Cone photoreceptor cells: 64.2;Epididymal principal cells: 104.9;Fibro-adipogenic progenitors: 37.3;Fibroblasts: 22.0;Gonadotrophs: 52.0;Granulosa cells: 32.4;Leydig cells: 58.6;Myonuclei: 27.0;Myosatellite cells: 40.2" "Cell type enhanced" "Detected in many" "astrocyte: 57.7;fibroblast: 64.8" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 5.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 5.0" "Adipose subcutaneous - Adipose progenitor cells, Lung - Fibroblasts_2, Minor Salivary Gland - Fibroblasts, Pituitary gland - Gonadotropes, Prostate - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008510, HPA008576" Approved Approved Approved Nucleoplasm,Cytosol NA NA 8200000 "Cluster 63: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 17 "Nucleoplasm, Cytosol" "HPA008510: , HPA008576: " "unprognostic (2.77e-1)" "unprognostic (1.17e-1)" "unprognostic (1.39e-1)" "unprognostic (8.76e-3)" "unprognostic (3.78e-3)" "unprognostic (2.86e-1)" "potential prognostic unfavorable (4.95e-4)" "unprognostic (1.48e-3)" "unprognostic (1.44e-1)" "unprognostic (4.81e-2)" "unprognostic (4.71e-3)" "unprognostic (1.36e-1)" IGF1 "IGF, IGF-I, IGF1A, IGFI" ENSG00000017427 "Insulin like growth factor 1" P05019 12 102395874-102481744 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Deafness, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 442.9;Decidual stromal cells: 728.0;Endometrial stromal cells: 1192.7;Fibroblasts: 514.9;Hepatocytes: 305.5;Hofbauer cells: 337.5;Leydig cells: 1189.9;Peritubular myoid cells: 252.0;Respiratory ionocytes: 701.1;Retinal bipolar cells: 215.6" "Group enriched" "Detected in many" 4 "central nervous system macrophage: 138.0;CGE interneuron: 256.9;LAMP5-LHX6 and Chandelier: 175.2;MGE interneuron: 160.0;midbrain-derived inhibitory: 274.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 2.4" "Lineage enriched" "Detected in single" 24 "B-cells: 2.4" "Group enriched" "Detected in many" 5 "Bone cancer: 7.3;Myeloma: 22.2" "Lung - Fibroblasts_2, Prostate - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA048946 Approved "Secreted to blood" "Growth factor" NA NA 103000000 120000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 24: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 108: Fibroblasts - ECM organization" 7 "HPA048946: " "unprognostic (1.07e-1)" "unprognostic (1.72e-1)" "unprognostic (5.96e-3)" "unprognostic (7.00e-3)" "unprognostic (3.11e-1)" "unprognostic (2.23e-1)" "unprognostic (4.67e-1)" "unprognostic (9.04e-2)" "unprognostic (1.63e-1)" "unprognostic (4.66e-1)" "unprognostic (6.02e-3)" "unprognostic (2.86e-2)" "unprognostic (3.07e-1)" "unprognostic (3.80e-3)" "potential prognostic favorable (2.84e-8)" "unprognostic (6.48e-2)" "unprognostic (1.05e-1)" "unprognostic (1.49e-2)" "unprognostic (6.49e-2)" "unprognostic (9.38e-2)" "unprognostic (1.42e-2)" "unprognostic (1.89e-1)" "unprognostic (4.17e-2)" "unprognostic (1.81e-2)" "unprognostic (1.03e-2)" "unprognostic (1.01e-1)" "unprognostic (3.47e-2)" "unprognostic (4.44e-3)" "unprognostic (1.03e-1)" "unprognostic (1.94e-1)" "unprognostic (5.98e-2)" IGF1R "CD221, IGFIR, IGFR, JTK13, MGC18216" ENSG00000140443 "Insulin like growth factor 1 receptor" P08069 15 98648539-98964530 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Host-virus interaction" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Neutrophils: 2488.0;Podocytes: 1295.1;Proximal tubule cells: 1339.2" "Cell type enhanced" "Detected in all" "endothelial cell: 1591.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.3" "Group enriched" "Detected in many" 6 "granulocytes: 4.3;T-cells: 1.4" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004822, CAB010268, HPA045563" Approved Approved "Nucleoli,Nucleoli rim,Plasma membrane,Primary cilium" NA NA 6800 "Cluster 35: Neutrophils - Protein binding" "Cluster 8: Pancreas - Proteolysis" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 58: Non-specific - Nuclear processes" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 128 "Nucleoli, Plasma membrane" "Nucleoli rim, Primary cilium" "CAB010268: , HPA004822: , HPA045563: " "unprognostic (1.45e-2)" "unprognostic (2.28e-2)" "unprognostic (2.15e-1)" "potential prognostic unfavorable (7.78e-4)" "unprognostic (2.57e-2)" "potential prognostic unfavorable (4.03e-5)" "unprognostic (1.43e-1)" "unprognostic (9.27e-3)" "unprognostic (4.46e-2)" "unprognostic (3.08e-1)" "validated prognostic favorable (3.89e-9)" "validated prognostic favorable (2.90e-4)" "unprognostic (1.95e-1)" "unprognostic (4.72e-2)" "unprognostic (5.61e-2)" "potential prognostic unfavorable (3.73e-4)" "unprognostic (1.75e-1)" "unprognostic (1.07e-1)" "unprognostic (1.66e-2)" "unprognostic (3.49e-1)" "unprognostic (8.00e-2)" "unprognostic (2.97e-2)" "unprognostic (2.84e-1)" "unprognostic (1.29e-2)" "unprognostic (1.20e-2)" "unprognostic (5.71e-2)" "unprognostic (2.20e-1)" "unprognostic (3.04e-1)" "unprognostic (6.77e-2)" "unprognostic (4.48e-3)" IGF2 "C11orf43, FLJ44734, IGF-II" ENSG00000167244 "Insulin like growth factor 2" P01344 11 2129112-2158391 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Carbohydrate metabolism, Glucose metabolism, Osteogenesis" "Growth factor, Hormone, Mitogen" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "placenta: 2597.9" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 92.5;Extravillous trophoblasts: 411.3;Fibroblasts: 56.2;Leydig cells: 138.2;Migrating cytotrophoblasts: 149.7;Syncytiotrophoblasts: 148.5;Thymic myoid cells: 304.6" "Group enriched" "Detected in some" 11 "fibroblast: 396.0;pericyte: 307.1;vascular associated smooth muscle cell: 105.5" "Cancer enhanced" "Detected in all" "Bladder Urothelial Carcinoma (TCGA): 958.2;Ovary Serous Cystadenocarcinoma (TCGA): 1031.2" "Region enhanced" "Detected in all" "choroid plexus: 618.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 597.2;Sarcoma: 625.3" "Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007556 Enhanced Approved "Golgi apparatus" "Secreted to blood" Hormone NA NA 609000000 520000000 "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 36: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 9 "Golgi apparatus" "HPA007556: " "unprognostic (3.37e-2)" "unprognostic (3.48e-1)" "unprognostic (1.18e-1)" "unprognostic (3.61e-2)" "unprognostic (2.42e-1)" "unprognostic (3.21e-1)" "unprognostic (6.18e-3)" "unprognostic (2.77e-1)" "unprognostic (1.19e-1)" "unprognostic (2.28e-1)" "unprognostic (1.65e-2)" "unprognostic (3.21e-2)" "potential prognostic unfavorable (2.28e-4)" "unprognostic (2.63e-3)" "unprognostic (5.39e-3)" "unprognostic (6.87e-2)" "unprognostic (4.74e-2)" "unprognostic (1.98e-1)" "unprognostic (2.09e-1)" "unprognostic (8.07e-3)" "potential prognostic unfavorable (4.85e-5)" "unprognostic (4.61e-2)" "unprognostic (1.30e-3)" "unprognostic (1.47e-1)" "unprognostic (1.64e-2)" "unprognostic (3.77e-2)" "unprognostic (7.35e-2)" "unprognostic (8.22e-3)" "unprognostic (2.04e-1)" "unprognostic (2.00e-2)" "unprognostic (2.75e-1)" IGF2BP1 IMP-1 ENSG00000159217 "Insulin like growth factor 2 mRNA binding protein 1" Q9NZI8 17 48997385-49056145 "Predicted intracellular proteins" "mRNA transport, Translation regulation, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "placenta: 5.1;testis: 4.5" "Cell type enhanced" "Detected in some" "Early primary spermatocytes: 60.5;Extravillous trophoblasts: 63.8;Gastric progenitor cells: 25.6;Hofbauer cells: 16.2;Migrating cytotrophoblasts: 29.2;Proximal tubule cells: 15.0;Undifferentiated spermatogonia: 56.2" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 19 "Testicular Germ Cell Tumor (TCGA): 58.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 102.7" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Testis - Spermatocytes, Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" "HPA021367, HPA062273" Enhanced Supported Cytosol NA NA 6600 "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 34: Testis cancer - Unknown function" "Cluster 108: Fibroblasts - ECM organization" 166 Cytosol "HPA021367: , HPA062273: " "potential prognostic unfavorable (2.81e-5)" "unprognostic (2.41e-1)" "unprognostic (4.86e-1)" "unprognostic (1.88e-2)" "unprognostic (2.21e-3)" "unprognostic (2.06e-1)" "unprognostic (9.86e-3)" "unprognostic (3.13e-2)" "potential prognostic unfavorable (6.16e-5)" "potential prognostic unfavorable (4.99e-8)" "unprognostic (5.54e-2)" "unprognostic (9.88e-3)" "unprognostic (2.16e-3)" "unprognostic (1.01e-1)" "unprognostic (9.01e-2)" "unprognostic (1.77e-2)" "unprognostic (2.02e-1)" "unprognostic (1.74e-2)" IGF2BP2 "IMP-2, p62" ENSG00000073792 "Insulin like growth factor 2 mRNA binding protein 2" Q9Y6M1 3 185643130-185825042 "Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA transport, Translation regulation, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 863.1;Endometrial glandular cells: 803.4;Endometrial luminal cells: 1276.8;Endometrial secretory cells: 726.3;Rod photoreceptor cells: 512.5" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 93.2;endothelial cell: 91.7;upper rhombic lip: 109.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Endothelial cells, Prostate - Fibroblasts, Spleen - Endothelial cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB017126, HPA035145" Enhanced Enhanced Cytosol NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 42: Retina - Visual perception" "Cluster 25: Non-specific - Transcription" "Cluster 72: Neuronal - Signal transduction" "Cluster 51: Secretory epithelial cells - Mixed function" 56 Cytosol "CAB017126: , HPA035145: " "unprognostic (3.79e-3)" "unprognostic (4.58e-2)" "unprognostic (1.15e-1)" "unprognostic (1.23e-1)" "unprognostic (8.15e-2)" "unprognostic (2.01e-1)" "unprognostic (2.58e-1)" "unprognostic (1.12e-2)" "potential prognostic unfavorable (1.93e-4)" "unprognostic (3.02e-1)" "potential prognostic unfavorable (8.28e-9)" "unprognostic (2.30e-2)" "unprognostic (1.95e-2)" "unprognostic (3.40e-3)" "unprognostic (4.31e-2)" "potential prognostic unfavorable (3.38e-4)" "unprognostic (5.99e-2)" "unprognostic (8.13e-2)" "potential prognostic favorable (3.24e-5)" "unprognostic (1.27e-1)" "unprognostic (2.03e-2)" "validated prognostic unfavorable (3.15e-4)" "validated prognostic unfavorable (4.04e-6)" "unprognostic (1.39e-1)" "unprognostic (1.92e-1)" "unprognostic (1.47e-1)" "unprognostic (1.19e-1)" "unprognostic (1.68e-1)" "unprognostic (5.48e-2)" "unprognostic (1.17e-1)" IGF2BP3 "CT98, IMP-3, IMP3" ENSG00000136231 "Insulin like growth factor 2 mRNA binding protein 3" O00425 7 23310209-23470491 "Predicted intracellular proteins" "mRNA transport, Translation regulation, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 6.9;placenta: 27.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 295.3;Esophageal apical cells: 143.8;Extravillous trophoblasts: 348.8;Gastric progenitor cells: 125.6;Hofbauer cells: 186.9;Megakaryocytes: 74.2;Migrating cytotrophoblasts: 213.1;Oocytes: 78.3;Platelets: 278.4;Syncytiotrophoblasts: 240.3;Undifferentiated spermatogonia: 74.3" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 23.7;LAMP5-LHX6 and Chandelier: 38.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA002037, HPA076951" Enhanced Supported Cytosol NA NA 6900 "Cluster 2: Dendritic cells - Unknown function" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 33: Neurons - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 122 Cytosol "HPA002037: , HPA076951: " "potential prognostic unfavorable (5.81e-4)" "unprognostic (3.63e-1)" "unprognostic (3.93e-2)" "unprognostic (3.40e-2)" "unprognostic (1.25e-1)" "unprognostic (2.47e-1)" "unprognostic (1.18e-2)" "unprognostic (2.49e-2)" "validated prognostic unfavorable (8.08e-12)" "validated prognostic unfavorable (8.24e-6)" "unprognostic (2.26e-3)" "potential prognostic unfavorable (2.63e-9)" "potential prognostic unfavorable (4.15e-4)" "unprognostic (1.27e-2)" "unprognostic (5.42e-2)" "unprognostic (5.54e-2)" "unprognostic (2.17e-1)" "unprognostic (4.31e-1)" "potential prognostic unfavorable (3.25e-5)" "unprognostic (1.18e-3)" "unprognostic (2.32e-1)" "unprognostic (7.42e-2)" "unprognostic (3.39e-2)" "unprognostic (2.57e-1)" "unprognostic (9.79e-2)" "potential prognostic unfavorable (1.72e-4)" "unprognostic (2.30e-2)" IGF2R "CD222, CI-M6PR, CI-MPR, CIMPR, M6P-R, MPR1, MPR300, MPRI" ENSG00000197081 "Insulin like growth factor 2 receptor" P11717 6 159969082-160113507 "Cancer-related genes, CD markers, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Neutrophils: 1973.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.4" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Colon - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009661, HPA011332" Supported Supported "Golgi apparatus,Vesicles" NA NA 130000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 28: Non-specific - Nuclear processes" "Cluster 24: Neutrophils - Innate immunity signal integration" 63 "Golgi apparatus" Vesicles "CAB009661: , HPA011332: " "unprognostic (3.42e-2)" "unprognostic (1.39e-3)" "unprognostic (3.72e-1)" "potential prognostic unfavorable (1.44e-4)" "unprognostic (3.01e-2)" "unprognostic (2.26e-1)" "unprognostic (8.47e-2)" "unprognostic (2.22e-2)" "unprognostic (1.14e-1)" "unprognostic (4.61e-3)" "potential prognostic favorable (1.61e-6)" "unprognostic (6.81e-2)" "unprognostic (1.05e-1)" "potential prognostic unfavorable (6.08e-4)" "unprognostic (5.16e-2)" "unprognostic (7.47e-2)" "unprognostic (1.41e-1)" "unprognostic (1.62e-1)" "unprognostic (1.21e-1)" "unprognostic (1.18e-2)" "unprognostic (1.53e-2)" "unprognostic (1.36e-1)" "unprognostic (9.04e-2)" "unprognostic (4.96e-2)" "unprognostic (1.12e-1)" "unprognostic (8.51e-3)" "unprognostic (2.11e-1)" "unprognostic (2.84e-1)" "unprognostic (2.21e-1)" "unprognostic (2.21e-1)" "unprognostic (2.61e-1)" IGFALS ALS ENSG00000099769 "Insulin like growth factor binding protein acid labile subunit" P35858 16 1790413-1794971 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "liver: 112.7" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 16.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA040692, HPA040948" Supported "Secreted to blood" "Cell adhesion" NA NA 14700000000 8300000000 "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 6: Non-specific - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 1 "HPA040692: , HPA040948: " "unprognostic (4.09e-3)" "unprognostic (3.85e-1)" "unprognostic (1.41e-2)" "unprognostic (7.78e-2)" "unprognostic (8.24e-3)" "unprognostic (1.15e-3)" "potential prognostic favorable (4.37e-5)" "potential prognostic favorable (1.90e-5)" "unprognostic (2.24e-1)" "unprognostic (6.87e-2)" "unprognostic (1.64e-2)" "unprognostic (6.79e-2)" "unprognostic (2.69e-1)" "unprognostic (2.12e-1)" "unprognostic (7.35e-3)" IGFBP1 "AFBP, hIGFBP-1, IBP1, IGF-BP25, PP12" ENSG00000146678 "Insulin like growth factor binding protein 1" P08833 7 45888360-45893660 "Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 1120.5" "Group enriched" "Detected in some" 17 "Decidual stromal cells: 1196.6;Hepatocytes: 1209.6" "Cell type enhanced" "Detected in single" "lower rhombic lip: 1.1" "Cancer enriched" "Detected in many" 16 "Liver Hepatocellular Carcinoma (TCGA): 538.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 38.2;liver cancer: 75.4;ovarian cancer: 50.4" "Adipose visceral - Mesothelial cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB004445, HPA046972, HPA050640" Enhanced Approved "Golgi apparatus" "Secreted to blood" Other NA NA 28100000 27000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 49: Hindbrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 93: Hepatocytes - Bile production & excretion" 4 "Golgi apparatus" "CAB004445: , HPA046972: , HPA050640: " "unprognostic (1.57e-2)" "unprognostic (1.31e-1)" "unprognostic (3.22e-3)" "unprognostic (1.36e-1)" "potential prognostic unfavorable (9.24e-7)" "unprognostic (5.58e-3)" "unprognostic (8.89e-2)" "unprognostic (8.70e-2)" "unprognostic (3.44e-1)" "potential prognostic unfavorable (2.02e-4)" "unprognostic (1.12e-1)" "unprognostic (9.01e-2)" "potential prognostic unfavorable (5.59e-7)" "potential prognostic unfavorable (3.01e-4)" "unprognostic (5.35e-2)" IGFBP2 IBP2 ENSG00000115457 "Insulin like growth factor binding protein 2" P18065 2 216632828-216664436 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth regulation" "Growth factor binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 1281.4;pancreas: 901.3" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 1705.8;Endometrial stromal cells: 1021.9;Gastric chief cells: 681.4;Hepatocytes: 823.4;Parietal cells: 1631.8;Respiratory ciliated cells: 825.5;Urothelial cells: 560.7" "Cell type enhanced" "Detected in many" "ependymal cell: 77.8;fibroblast: 151.1;vascular associated smooth muscle cell: 68.4" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 8 "choroid plexus: 238.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Pancreas - Exocrine glandular cells, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077723 Approved "Endoplasmic reticulum" "Secreted to blood" Other NA NA 303000000 280000000 "Cluster 70: Non-specific - Protein processing" "Cluster 23: Choroid plexus - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 108: Fibroblasts - ECM organization" 5 "Endoplasmic reticulum" "HPA077723: " "unprognostic (2.36e-1)" "unprognostic (2.46e-1)" "unprognostic (4.82e-2)" "unprognostic (1.12e-1)" "unprognostic (1.27e-1)" "unprognostic (1.57e-1)" "unprognostic (7.35e-3)" "unprognostic (1.41e-2)" "unprognostic (1.24e-2)" "unprognostic (3.01e-1)" "unprognostic (7.04e-2)" "unprognostic (3.36e-2)" "potential prognostic unfavorable (5.02e-4)" "unprognostic (2.29e-1)" "unprognostic (1.02e-2)" "unprognostic (8.62e-2)" "unprognostic (2.12e-1)" "unprognostic (3.86e-2)" "unprognostic (1.18e-2)" "unprognostic (2.02e-1)" "unprognostic (1.71e-1)" "potential prognostic favorable (4.28e-4)" "unprognostic (1.64e-1)" "unprognostic (1.03e-1)" "unprognostic (9.03e-2)" "unprognostic (4.18e-2)" "potential prognostic unfavorable (5.28e-5)" "unprognostic (8.25e-2)" "unprognostic (1.17e-1)" "unprognostic (9.88e-3)" "unprognostic (1.89e-1)" IGFBP3 "BP-53, IBP3" ENSG00000146674 "Insulin like growth factor binding protein 3" P17936 7 45912245-45921874 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Apoptosis "Growth factor binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 1748.7" "Cell type enriched" "Detected in many" 4 "Extravillous trophoblasts: 3322.2" "Cell type enriched" "Detected in many" 4 "endothelial cell: 105.8" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 1591.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "plasmacytoid DC: 48.9" "Lineage enriched" "Detected in many" 5 "dendritic cells: 48.9" "Cancer enriched" "Detected in all" 5 "Kidney cancer: 3358.0" "Liver - Hepatic stellate cells, Prostate - Fibroblasts, Stomach - Fibroblasts, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" CAB010360 Uncertain Vesicles "Secreted to blood" Other NA NA 3250000000 1400000000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 49: Hindbrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 16 Vesicles "CAB010360: " "unprognostic (2.27e-1)" "unprognostic (6.80e-3)" "unprognostic (3.27e-2)" "unprognostic (7.85e-2)" "unprognostic (1.39e-2)" "potential prognostic unfavorable (5.18e-5)" "unprognostic (3.99e-2)" "unprognostic (1.95e-3)" "unprognostic (6.62e-2)" "unprognostic (7.40e-3)" "unprognostic (1.24e-1)" "unprognostic (1.97e-1)" "potential prognostic unfavorable (7.23e-5)" "potential prognostic unfavorable (1.96e-4)" "unprognostic (1.33e-2)" "unprognostic (1.94e-2)" "unprognostic (1.45e-2)" "unprognostic (2.64e-2)" "unprognostic (3.62e-2)" "unprognostic (2.97e-1)" "unprognostic (2.18e-1)" "unprognostic (6.13e-3)" "unprognostic (3.86e-1)" "unprognostic (1.92e-1)" "potential prognostic unfavorable (3.20e-4)" "unprognostic (1.11e-1)" "unprognostic (2.17e-2)" "unprognostic (7.51e-2)" "unprognostic (1.37e-1)" "unprognostic (1.57e-2)" "unprognostic (3.76e-2)" IGFBP4 "BP-4, HT29-IGFBP, IBP4, IGFBP-4" ENSG00000141753 "Insulin like growth factor binding protein 4" P22692 17 40443450-40457725 "Plasma proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 1247.1;Endometrial stromal cells: 421.7;Epididymal efferent duct absorptive cells: 391.0;Fibroblasts: 760.7;Hepatocytes: 587.9;Hofbauer cells: 626.1;Lymphatic endothelial cells: 434.3;Ovarian stromal cells: 343.1;Pericytes: 437.6;Vascular endothelial cells: 628.2;Vascular smooth muscle cells: 304.0" "Cell type enhanced" "Detected in many" "endothelial cell: 60.4;fibroblast: 99.7;vascular associated smooth muscle cell: 109.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "MAIT T-cell: 19.6;NK-cell: 37.1" "Group enriched" "Detected in many" 5 "NK-cells: 37.1;T-cells: 19.6" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Pituitary gland - Endothelial cells, Skeletal muscle - Endothelial cells, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066240 Supported "Secreted to blood" Other NA NA 227000000 260000000 "Cluster 15: NK-cells - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 27 "HPA066240: " "unprognostic (2.05e-2)" "unprognostic (1.10e-2)" "unprognostic (1.03e-2)" "unprognostic (1.44e-1)" "unprognostic (1.51e-1)" "unprognostic (2.86e-2)" "potential prognostic unfavorable (7.27e-5)" "unprognostic (1.88e-2)" "unprognostic (5.12e-1)" "unprognostic (2.98e-1)" "unprognostic (6.78e-2)" "potential prognostic favorable (2.56e-5)" "unprognostic (2.63e-3)" "unprognostic (1.22e-3)" "unprognostic (9.24e-3)" "unprognostic (1.42e-1)" "unprognostic (3.15e-1)" "unprognostic (5.86e-2)" "unprognostic (1.07e-1)" "unprognostic (1.15e-2)" "unprognostic (1.23e-1)" "unprognostic (1.23e-1)" "unprognostic (2.59e-1)" "unprognostic (6.57e-2)" "unprognostic (2.15e-1)" "unprognostic (3.71e-2)" "potential prognostic unfavorable (1.28e-4)" "unprognostic (3.81e-2)" "unprognostic (1.19e-1)" "unprognostic (1.11e-1)" "unprognostic (2.52e-2)" IGFBP5 ENSG00000115461 "Insulin like growth factor binding protein 5" P24593 2 216672105-216695549 "Plasma proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 1401.0" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 3181.2;Fibroblasts: 1931.8;Leydig cells: 1574.6;Medullary thymic epithelial cells: 4066.0;Müller glia: 903.7;Myosatellite cells: 1198.9;Ovarian stromal cells: 2470.0;Pericytes: 1809.1;Peritubular myoid cells: 923.4;Pituitary stem cells: 995.9;Vascular smooth muscle cells: 1620.0" "Cell type enhanced" "Detected in many" "fibroblast: 373.6;vascular associated smooth muscle cell: 233.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 337.9;breast cancer: 378.2" "Pancreas - Fibroblasts, Pituitary gland - Fibroblasts, Skin - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040514, HPA070407" Supported Approved Vesicles "Secreted to blood" Other NA NA 110000000 170000000 "Cluster 75: Ovary - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 80 Vesicles "HPA040514: , HPA070407: " "unprognostic (1.42e-1)" "unprognostic (1.58e-1)" "unprognostic (1.66e-1)" "unprognostic (6.60e-2)" "unprognostic (3.38e-2)" "unprognostic (2.94e-2)" "unprognostic (3.53e-2)" "unprognostic (8.92e-3)" "unprognostic (2.79e-1)" "unprognostic (1.21e-1)" "unprognostic (1.05e-2)" "potential prognostic favorable (9.90e-4)" "potential prognostic unfavorable (3.08e-4)" "unprognostic (6.95e-2)" "unprognostic (9.29e-3)" "unprognostic (2.77e-2)" "unprognostic (9.28e-3)" "unprognostic (8.16e-2)" "unprognostic (1.48e-1)" "unprognostic (3.33e-2)" "unprognostic (2.76e-1)" "unprognostic (3.13e-1)" "unprognostic (1.33e-1)" "unprognostic (2.29e-2)" "unprognostic (5.06e-1)" "unprognostic (1.42e-2)" "unprognostic (4.31e-2)" "unprognostic (1.29e-2)" "unprognostic (1.91e-1)" "unprognostic (7.02e-2)" "unprognostic (1.08e-1)" IGFBP6 ENSG00000167779 "Insulin like growth factor binding protein 6" P24592 12 53097436-53102345 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 786.7" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 1549.6;Fibroblasts: 2165.8;Hepatic stellate cells: 632.6;Leydig cells: 720.9;Pericytes: 663.3;Peritubular myoid cells: 1382.1;Pituicytes/FSCs: 324.7;Vascular smooth muscle cells: 402.7" "Cell type enriched" "Detected in many" 6 "fibroblast: 333.0" "Cancer enhanced" "Detected in all" "Kidney Renal Papillary Cell Carcinoma (TCGA): 525.1;Thyroid Carcinoma (TCGA): 460.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 31.7;non-classical monocyte: 20.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Colon - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblasts_2, Minor Salivary Gland - Fibroblasts, Skin - Fibroblasts_2, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "spinal cord: 139.2" "HPA008005, HPA075088" Approved "Secreted to blood" Other NA NA 199000000 160000000 "Cluster 45: Eosinophils - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 37 "HPA008005: , HPA075088: " "unprognostic (2.09e-1)" "unprognostic (1.07e-2)" "unprognostic (2.50e-3)" "unprognostic (3.96e-1)" "unprognostic (8.10e-3)" "unprognostic (1.77e-1)" "potential prognostic unfavorable (5.75e-5)" "unprognostic (9.41e-2)" "unprognostic (2.71e-1)" "unprognostic (3.36e-2)" "unprognostic (1.04e-1)" "unprognostic (1.46e-1)" "potential prognostic favorable (2.78e-4)" "unprognostic (6.46e-2)" "unprognostic (1.22e-1)" "unprognostic (1.74e-2)" "unprognostic (4.53e-3)" "unprognostic (2.46e-2)" "unprognostic (8.14e-2)" "unprognostic (3.44e-2)" "unprognostic (1.18e-1)" "unprognostic (3.95e-2)" "unprognostic (1.40e-1)" "unprognostic (2.05e-2)" "unprognostic (1.65e-1)" "potential prognostic favorable (1.88e-4)" "unprognostic (5.26e-2)" "unprognostic (2.91e-3)" "unprognostic (2.30e-1)" "unprognostic (2.11e-1)" "unprognostic (7.31e-2)" IGFBP7 "FSTL2, IGFBP-7, MAC25, PSF" ENSG00000163453 "Insulin like growth factor binding protein 7" Q16270 4 57030773-57110385 "Disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 4198.0" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 3075.8;Epididymal efferent duct ciliated cells: 2678.6;Fallopian tube ciliated cells: 2645.9;Fibroblasts: 2669.1;Hepatic stellate cells: 7539.2;Leydig cells: 8234.1;Lymphatic endothelial cells: 2966.9;Pericytes: 5056.4;Peritubular myoid cells: 11371.6;Vascular endothelial cells: 2322.1;Vascular smooth muscle cells: 4156.9" "Group enriched" "Detected in many" 6 "choroid plexus epithelial cell: 1798.7;endothelial cell: 924.5;pericyte: 2548.6;vascular associated smooth muscle cell: 2059.2" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 8 "choroid plexus: 2654.6" "Immune cell enhanced" "Detected in many" "eosinophil: 21.8" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 739.6;Kidney cancer: 772.0" "Adrenal gland - Fibroblasts, Breast - Endothelial cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Pituitary gland - Fibroblasts, Prostate - Fibroblasts, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002196, CAB020668" Approved Approved "Golgi apparatus" "Secreted to blood" "Cell adhesion" NA NA 30300000 43000000 "Cluster 45: Eosinophils - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 110: Mural cells - ECM organization" 2 "Golgi apparatus" "CAB020668: , HPA002196: " "unprognostic (5.94e-2)" "unprognostic (1.04e-1)" "potential prognostic unfavorable (5.81e-4)" "potential prognostic unfavorable (5.56e-4)" "unprognostic (8.09e-3)" "unprognostic (6.80e-2)" "unprognostic (2.33e-1)" "unprognostic (8.51e-2)" "unprognostic (1.91e-1)" "unprognostic (1.29e-1)" "potential prognostic favorable (3.43e-4)" "unprognostic (3.87e-2)" "unprognostic (4.78e-2)" "unprognostic (7.52e-2)" "unprognostic (1.28e-2)" "unprognostic (4.25e-1)" "unprognostic (9.40e-2)" "unprognostic (1.01e-2)" "unprognostic (3.74e-2)" "unprognostic (1.43e-2)" "unprognostic (2.57e-2)" "unprognostic (9.66e-2)" "unprognostic (3.05e-2)" "unprognostic (6.31e-2)" "unprognostic (1.50e-1)" "unprognostic (3.01e-2)" "unprognostic (7.36e-2)" "potential prognostic unfavorable (3.80e-4)" "unprognostic (2.45e-1)" "unprognostic (1.03e-1)" "unprognostic (6.41e-2)" IGFBPL1 bA113O24.1 ENSG00000137142 "Insulin like growth factor binding protein like 1" Q8WX77 9 38406528-38424454 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "blood vessel: 7.8;thyroid gland: 15.5" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 21.3;Brain inhibitory neurons: 10.3;Cholangiocytes: 8.6;Early spermatids: 24.8;Gonadotrophs: 8.9;Hofbauer cells: 15.8;Lactotrophs: 14.2;Late spermatids: 21.3;Neuroendocrine cells: 14.6;Oligodendrocyte progenitor cells: 7.8;Pancreatic islet cells: 21.0;Paneth cells: 11.6;Smooth muscle cells: 9.1;Somatotrophs: 16.9" "Cell type enhanced" "Detected in many" "midbrain-derived inhibitory: 24.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "Neuroblastoma: 122.0;testis cancer: 222.3" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Adrenal gland - Adrenal medulla cells, Kidney - Proximal tubular cells, Pancreas - Alpha cells, Pituitary gland - Lactotropes, Prostate - Smooth muscle cells, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA051354 Uncertain Uncertain Nucleoplasm,Vesicles "Secreted to blood" "No annotated function" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" "Nucleoplasm, Vesicles" "HPA051354: " "unprognostic (2.35e-1)" "unprognostic (1.39e-1)" "unprognostic (1.30e-1)" "unprognostic (4.23e-2)" "unprognostic (4.64e-2)" "unprognostic (4.63e-2)" "unprognostic (7.16e-2)" "potential prognostic favorable (6.99e-4)" "unprognostic (2.51e-1)" "unprognostic (1.37e-2)" "unprognostic (8.13e-3)" "unprognostic (2.42e-1)" "potential prognostic favorable (1.31e-5)" "unprognostic (2.37e-1)" "unprognostic (4.60e-2)" "potential prognostic favorable (3.91e-4)" "unprognostic (4.66e-2)" "unprognostic (3.05e-1)" "unprognostic (7.09e-2)" "unprognostic (3.50e-2)" "unprognostic (1.01e-1)" IGFL1 UNQ644 ENSG00000188293 "IGF like family member 1" Q6UW32 19 46229742-46231243 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 114.5;salivary gland: 29.5;vagina: 32.6" "Cell type enhanced" "Detected in some" "Esophageal apical cells: 675.6;Esophageal suprabasal cells: 117.6;Suprabasal keratinocytes: 187.7" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 139.2;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 89.9;Head and Neck Squamous Cell Carcinoma (TCGA): 98.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder cancer: 30.2;head and neck cancer: 34.3" HPA014001 Uncertain "Secreted in other tissues" "No annotated function" NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 2 "HPA014001: " "unprognostic (6.40e-2)" "unprognostic (1.50e-1)" "unprognostic (2.47e-1)" "unprognostic (1.73e-1)" "unprognostic (2.41e-2)" "unprognostic (2.92e-2)" "unprognostic (9.36e-2)" "unprognostic (1.15e-1)" "potential prognostic unfavorable (3.74e-4)" "unprognostic (2.74e-3)" "unprognostic (9.48e-2)" "unprognostic (9.35e-3)" "unprognostic (1.45e-3)" "unprognostic (1.28e-1)" "unprognostic (2.98e-1)" "unprognostic (6.69e-2)" IGFL2 UNQ645 ENSG00000204866 "IGF like family member 2" Q6UWQ7 19 46143106-46161298 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "skin 1: 39.9" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 2.8;Decidual stromal cells: 3.1;Differentiating spermatogonia: 6.8;Early primary spermatocytes: 7.2;Early spermatids: 6.2;Enteric transient amplifying cells: 2.5;Esophageal suprabasal cells: 2.6;Late primary spermatocytes: 7.1;Late spermatids: 6.8;Mesothelial cells: 2.4;Migrating cytotrophoblasts: 4.7;Retinal ganglion cells: 3.9;Suprabasal keratinocytes: 9.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Pancreatic Adenocarcinoma (TCGA): 35.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Rhabdoid: 102.4" "Adipose visceral - Mesothelial cells, Testis - Early spermatids" HPA059137 Uncertain Approved "Nucleoplasm,Plasma membrane" "Secreted in other tissues" "No annotated function" NA NA "Cluster 37: Skin - Keratinization" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 85: Squamous epithelial cells - Keratinization" Nucleoplasm "Plasma membrane" "HPA059137: " "unprognostic (2.62e-1)" "unprognostic (3.10e-1)" "unprognostic (1.81e-1)" "unprognostic (3.99e-2)" "unprognostic (2.12e-1)" "unprognostic (7.68e-2)" "unprognostic (1.00e-1)" "unprognostic (3.31e-1)" "unprognostic (1.35e-1)" "unprognostic (2.19e-1)" "unprognostic (7.94e-2)" "unprognostic (2.85e-2)" "unprognostic (2.10e-1)" "unprognostic (1.18e-2)" "unprognostic (6.40e-3)" "unprognostic (2.10e-2)" "unprognostic (8.25e-2)" "unprognostic (1.94e-1)" "unprognostic (2.94e-2)" "unprognostic (1.05e-1)" "unprognostic (3.08e-3)" "unprognostic (8.04e-2)" IGFL3 UNQ483 ENSG00000188624 "IGF like family member 3" Q6UXB1 19 46120067-46124688 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "skin 1: 25.7" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 1.5;Cone photoreceptor cells: 2.1;Kupffer cells: 2.0;Late spermatids: 1.1;Medullary thymic epithelial cells: 4.8;Suprabasal keratinocytes: 6.3" "Cell type enhanced" "Detected in single" "Bergmann glia: 1.8" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 9.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "Rhabdoid: 213.3" HPA062776 Uncertain "Secreted in other tissues" "No annotated function" NA NA "Cluster 37: Skin - Keratinization" "Cluster 9: Non-specific - Receptor signaling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 26: Keratinocytes - Keratinization" "HPA062776: " "unprognostic (6.98e-2)" "unprognostic (1.19e-1)" "unprognostic (3.26e-1)" "unprognostic (1.75e-1)" "unprognostic (1.93e-1)" "unprognostic (9.39e-2)" "unprognostic (9.85e-2)" "unprognostic (6.42e-2)" "potential prognostic unfavorable (1.37e-4)" "unprognostic (4.42e-2)" "unprognostic (1.50e-1)" IGFL4 ENSG00000204869 "IGF like family member 4" Q6B9Z1 19 46039182-46077118 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 4 "retina: 46.4;skin 1: 12.4" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 26.0;Brain inhibitory neurons: 32.7;Cone photoreceptor cells: 35.2;Gonadotrophs: 49.0;Lactotrophs: 22.2;Oligodendrocyte progenitor cells: 19.1;Other brain neurons: 21.0;Retinal bipolar cells: 31.6;Retinal ganglion cells: 15.5;Rod photoreceptor cells: 90.0;Somatotrophs: 19.8;Thyrotrophs: 32.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" HPA047655 Approved Approved Cytosol "Secreted - unknown location" "No annotated function" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 42: Retina - Visual perception" "Cluster 9: Non-specific - Receptor signaling" "Cluster 56: Non-specific - Sensory perception" "Cluster 79: Photoreceptor cells - Phototransduction" Cytosol "HPA047655: " "unprognostic (4.56e-2)" "unprognostic (2.56e-3)" "unprognostic (5.34e-2)" "unprognostic (8.91e-2)" "unprognostic (3.95e-2)" "unprognostic (1.12e-2)" "unprognostic (2.97e-2)" "unprognostic (4.30e-1)" "unprognostic (1.94e-1)" "unprognostic (4.42e-2)" IGFLR1 "FLJ22573, TMEM149, U2AF1L4" ENSG00000126246 "IGF like family receptor 1" Q9H665 19 35738801-35742453 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 47.1" "Cell type enhanced" "Detected in many" "cDC: 17.1;Hepatocytes: 22.1;Hofbauer cells: 13.0;Macrophages: 8.8;Mast cells: 7.7;Microglia: 8.3;monocytes: 10.3;NK-cells: 7.8;pDCs: 23.0;Plasma cells: 9.9;Tuft cells: 11.5" "Group enriched" "Detected in many" 4 "central nervous system macrophage: 12.1;leukocyte: 22.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 901.7" "Lineage enriched" "Detected in all" 4 "dendritic cells: 901.7" "Cancer enhanced" "Detected in all" "Myeloma: 17.3" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Heart muscle - Macrophages, Spleen - T-cells" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA012369, HPA070778" Uncertain Approved "Nucleoplasm,Plasma membrane" "Intracellular and membrane" Receptor NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 44: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 67: Plasma cells - Plasma cell differentiation" 1 "Nucleoplasm, Plasma membrane" "HPA012369: , HPA070778: " "unprognostic (4.61e-2)" "potential prognostic favorable (6.28e-4)" "unprognostic (8.26e-3)" "unprognostic (2.65e-1)" "unprognostic (1.90e-1)" "unprognostic (1.55e-3)" "unprognostic (3.56e-3)" "potential prognostic favorable (6.66e-5)" "unprognostic (2.49e-2)" "potential prognostic unfavorable (1.02e-5)" "unprognostic (1.09e-1)" "unprognostic (6.83e-2)" "unprognostic (1.90e-1)" "unprognostic (1.55e-1)" "unprognostic (6.53e-3)" "unprognostic (1.36e-1)" "unprognostic (3.40e-1)" "unprognostic (2.78e-1)" "unprognostic (5.71e-2)" "unprognostic (2.00e-2)" "unprognostic (4.13e-3)" "unprognostic (6.25e-2)" "unprognostic (3.06e-1)" "unprognostic (2.28e-1)" "unprognostic (4.77e-2)" "unprognostic (7.10e-2)" "unprognostic (3.27e-1)" "unprognostic (1.73e-1)" "unprognostic (3.01e-1)" "unprognostic (8.72e-2)" IGFN1 "DKFZp434B1231, EEF1A2BP1" ENSG00000163395 "Immunoglobulin like and fibronectin type III domain containing 1" Q86VF2 1 201190824-201228952 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "skeletal muscle: 174.5" "Cell type enhanced" "Detected in some" "Astrocytes: 21.6;Leydig cells: 47.1;Myonuclei: 81.7;Pancreatic acinar cells: 86.2;Peritubular myoid cells: 17.2;Thymic myoid cells: 295.0" "Cell type enhanced" "Detected in some" "astrocyte: 23.6;choroid plexus epithelial cell: 12.0" "Group enriched" "Detected in some" 6 "Kidney Renal Papillary Cell Carcinoma (TCGA): 5.0;Thyroid Carcinoma (TCGA): 9.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 180.0;Rhabdoid: 98.7" "Testis - Peritubular cells" "Group enriched" "Detected in many" 7 "amygdala: 3.3;basal ganglia: 1.2;cerebral cortex: 2.9;hippocampal formation: 1.9" "Low region specificity" "Detected in some" HPA050415 Enhanced Approved "Midbody ring" Yes NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 29: Forebrain - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 2 "Midbody ring" "HPA050415: " "unprognostic (6.63e-2)" "unprognostic (4.46e-2)" "validated prognostic unfavorable (2.09e-10)" "validated prognostic unfavorable (5.51e-4)" "unprognostic (8.08e-3)" "unprognostic (1.81e-2)" "unprognostic (1.99e-1)" IGHA1 AL928768.3 ENSG00000211895 "Immunoglobulin heavy constant alpha 1" P01876 14 105703995-105708665 "Disease related genes, Immunoglobulin genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 6976.0;lymphoid tissue: 5886.0;salivary gland: 8576.2;stomach 1: 6273.4" "Cell type enriched" "Detected in some" 18 "Plasma cells: 9025.7" "Cell type enriched" "Detected in single" 253 "leukocyte: 25.4" "Cancer enhanced" "Detected in all" "Lung Adenocarcinoma (TCGA): 2831.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 203 "memory B-cell: 2579.2;naive B-cell: 1123.4" "Lineage enriched" "Detected in many" 282 "B-cells: 2579.2" "Cancer enriched" "Detected in some" 20 "Myeloma: 1517.6" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "HPA001217, HPA006013" Approved "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 17: Intestine - Digestion" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 67: Plasma cells - Plasma cell differentiation" 29 "HPA001217: , HPA006013: " "unprognostic (2.06e-1)" "potential prognostic favorable (1.77e-5)" "unprognostic (4.87e-2)" "unprognostic (2.00e-2)" "unprognostic (2.64e-1)" "unprognostic (6.39e-3)" "unprognostic (2.52e-2)" "potential prognostic favorable (1.23e-4)" "unprognostic (1.43e-1)" "unprognostic (1.12e-2)" "unprognostic (7.50e-2)" "unprognostic (2.41e-3)" "unprognostic (1.50e-1)" "unprognostic (3.01e-2)" "unprognostic (2.73e-2)" "unprognostic (1.00e-1)" "unprognostic (1.29e-1)" "unprognostic (4.90e-2)" "unprognostic (2.15e-1)" "unprognostic (2.00e-1)" "unprognostic (5.12e-3)" "unprognostic (2.85e-1)" "unprognostic (2.69e-2)" "unprognostic (1.95e-1)" "unprognostic (4.11e-1)" "unprognostic (5.33e-2)" "unprognostic (7.17e-2)" "unprognostic (9.53e-2)" "unprognostic (6.81e-2)" IGHA2 ENSG00000211890 "Immunoglobulin heavy constant alpha 2 (A2m marker)" P01877 14 105583731-105588395 "Immunoglobulin genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 5009.9;salivary gland: 3590.5" "Cell type enriched" "Detected in some" 5 "Plasma cells: 8042.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 878 "memory B-cell: 280.4;naive B-cell: 124.8" "Lineage enriched" "Detected in single" 1215 "B-cells: 280.4" "Cancer enriched" "Detected in some" 5 "Myeloma: 47.8" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "HPA001217, HPA006013" Approved "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 77: Intestine - Digestion" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 67: Plasma cells - Plasma cell differentiation" 17 "HPA001217: , HPA006013: " "unprognostic (5.24e-2)" "unprognostic (1.79e-3)" "potential prognostic favorable (6.50e-5)" "unprognostic (3.36e-1)" "unprognostic (1.99e-1)" "unprognostic (5.28e-2)" "unprognostic (1.09e-3)" "unprognostic (5.05e-3)" "unprognostic (9.02e-3)" "potential prognostic unfavorable (3.47e-4)" "unprognostic (2.49e-1)" "unprognostic (8.14e-2)" "unprognostic (1.27e-1)" "unprognostic (2.80e-2)" "unprognostic (7.91e-2)" "unprognostic (3.28e-1)" "unprognostic (1.31e-1)" "unprognostic (2.30e-1)" "unprognostic (1.95e-2)" "unprognostic (6.25e-2)" "unprognostic (2.31e-2)" "unprognostic (4.24e-1)" "unprognostic (5.27e-2)" "unprognostic (2.61e-2)" "unprognostic (2.17e-1)" "unprognostic (4.34e-3)" "unprognostic (3.82e-1)" IGHD "FLJ00382, FLJ46727, MGC29633" ENSG00000211898 "Immunoglobulin heavy constant delta" 14 105836765-105845677 "Immunoglobulin genes, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 109.7;salivary gland: 73.7" "Cell type enriched" "Detected in some" 19 "Plasma cells: 1545.7" "Cell type enriched" "Detected in single" 25 "leukocyte: 6.4" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 139.9;Lung Squamous Cell Carcinoma (TCGA): 112.8" "Not detected" "Not detected" "Group enriched" "Detected in some" 62 "memory B-cell: 147.4;naive B-cell: 464.1" "Lineage enriched" "Detected in many" 95 "B-cells: 464.1" "Cancer enriched" "Detected in some" 38 "Myeloma: 1117.7" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Skin - Plasma cells" "Not detected" "Not detected" CAB012703 Approved NA NA "Cluster 34: B-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 44: Plasma cells - Antibody production & secretion" "CAB012703: " "unprognostic (2.72e-3)" "potential prognostic favorable (3.91e-6)" "unprognostic (4.66e-3)" "unprognostic (3.65e-1)" "unprognostic (1.02e-1)" "unprognostic (4.42e-3)" "unprognostic (2.76e-1)" "unprognostic (1.35e-1)" "unprognostic (1.64e-1)" "unprognostic (5.58e-2)" "unprognostic (1.56e-1)" "unprognostic (2.20e-2)" "unprognostic (2.04e-3)" "unprognostic (4.83e-2)" "unprognostic (3.50e-1)" "unprognostic (1.73e-1)" "unprognostic (1.15e-1)" "unprognostic (9.62e-2)" "unprognostic (4.03e-1)" "unprognostic (2.46e-1)" "unprognostic (5.56e-3)" "unprognostic (1.24e-1)" "unprognostic (2.19e-2)" "unprognostic (3.05e-2)" "unprognostic (3.14e-1)" "unprognostic (9.21e-3)" "unprognostic (1.76e-1)" IGHD1-1 IGHD11 ENSG00000236170 "Immunoglobulin heavy diversity 1-1" P0DOY5 14 105919502-105919518 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immunoglobulin genes" Immunity NA NA IGHD1-14 "DM2, IGHD114" ENSG00000227108 "Immunoglobulin heavy diversity 1-14 (non-functional)" 14 105900638-105900654 "Immunoglobulin genes, Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA IGHD1-20 IGHD120 ENSG00000237020 "Immunoglobulin heavy diversity 1-20" 14 105891191-105891207 "Immunoglobulin genes, Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA IGHD1-26 IGHD126 ENSG00000211907 "Immunoglobulin heavy diversity 1-26" 14 105881034-105881053 "Immunoglobulin genes, Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA IGHD1-7 "DM1, IGHD17" ENSG00000237197 "Immunoglobulin heavy diversity 1-7" 14 105909907-105909923 "Immunoglobulin genes, Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA IGHD1OR15-1A "IGHD1/OR15-1A, IGHD1OR151A" ENSG00000271336 "Immunoglobulin heavy diversity 1/OR15-1A (non-functional)" 15 20011153-20011169 "Immunoglobulin genes, Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA IGHD1OR15-1B "IGHD1/OR15-1B, IGHD1OR151B" ENSG00000270185 "Immunoglobulin heavy diversity 1/OR15-1B (non-functional)" 15 21017800-21017816 "Immunoglobulin genes, Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA IGHD2-15 "D2, IGHD215" ENSG00000211918 "Immunoglobulin heavy diversity 2-15" 14 105897957-105897987 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "bone marrow: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 8 "naive B-cell: 39.7" "Lineage enriched" "Detected in single" 397 "B-cells: 39.7" "Cancer enriched" "Detected in single" 16 "Leukemia: 4.4" "Breast - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "unprognostic (2.39e-1)" IGHD2-2 IGHD22 ENSG00000211931 "Immunoglobulin heavy diversity 2-2" 14 105916826-105916856 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 14 "bone marrow: 3.1;intestine: 2.4;lymphoid tissue: 2.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "naive B-cell: 3.0" "Lineage enriched" "Detected in single" 31 "B-cells: 3.0" "Group enriched" "Detected in some" 18 "Leukemia: 5.7;Myeloma: 7.5" "Breast - Plasma cells, Minor Salivary Gland - Plasma cells, Stomach - Plasma cells" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 51: Myeloma - Immunoglobulins" "unprognostic (7.75e-1)" IGHD2-21 IGHD221 ENSG00000211912 "Immunoglobulin heavy diversity 2-21" 14 105888551-105888578 "Immunoglobulin genes, Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Plasma cells, Minor Salivary Gland - Plasma cells, Stomach - Plasma cells" NA NA IGHD2-8 "DLR1, IGHD28" ENSG00000211925 "Immunoglobulin heavy diversity 2-8" 14 105907211-105907241 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 4 "bone marrow: 1.8;lymphoid tissue: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 33 "naive B-cell: 3.2" "Lineage enriched" "Detected in single" 33 "B-cells: 3.2" "Cancer enriched" "Detected in single" 8 "Leukemia: 3.8" NA NA "Cluster 15: Bone marrow - Innate immune response" "Cluster 14: Myeloid leukemia - Innate immune response" IGHD2OR15-2A "IGHD2/OR15-2A, IGHD2OR152A" ENSG00000282599 "Immunoglobulin heavy diversity 2/OR15-2A (non-functional)" 15 20008402-20008432 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Gallbladder cancer: 1.5" NA NA "Cluster 49: Hindbrain - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" IGHD2OR15-2B "IGHD2/OR15-2B, IGHD2OR152B" ENSG00000282268 "Immunoglobulin heavy diversity 2/OR15-2B (non-functional)" 15 21015048-21015078 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Gallbladder cancer: 1.5" NA NA "Cluster 49: Hindbrain - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" IGHD3-10 "DXP'1, IGHD310" ENSG00000211923 "Immunoglobulin heavy diversity 3-10" 14 105904497-105904527 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 8 "bone marrow: 1.2;intestine: 3.5;lymphoid tissue: 3.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 6 "naive B-cell: 5.4" "Lineage enriched" "Detected in single" 55 "B-cells: 5.4" "Cancer enriched" "Detected in single" 10 "Leukemia: 4.8" "Breast - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Prostate - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "unprognostic (3.07e-1)" IGHD3-16 IGHD316 ENSG00000211917 "Immunoglobulin heavy diversity 3-16" 14 105895634-105895670 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 4 "bone marrow: 3.7;intestine: 2.5;lymphoid tissue: 3.8" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Testicular Germ Cell Tumor (TCGA): 3.5" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 7 "naive B-cell: 27.0" "Lineage enriched" "Detected in many" 12 "B-cells: 27.0" "Cancer enriched" "Detected in single" 24 "Leukemia: 4.5" "Minor Salivary Gland - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "unprognostic (3.08e-1)" "unprognostic (1.13e-2)" IGHD3-22 IGHD322 ENSG00000211911 "Immunoglobulin heavy diversity 3-22" 14 105886031-105886061 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "intestine: 1.5;lymphoid tissue: 2.9;stomach 1: 2.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 5 "naive B-cell: 48.4" "Lineage enriched" "Detected in many" 7 "B-cells: 48.4" "Cancer enriched" "Detected in single" 8 "Leukemia: 1.5" "Breast - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 14: Myeloid leukemia - Innate immune response" IGHD3-3 "DXP4, IGHD33" ENSG00000211930 "Immunoglobulin heavy diversity 3-3" 14 105914359-105914389 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "bone marrow: 4.0;lymphoid tissue: 2.7;salivary gland: 3.5" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "Testicular Germ Cell Tumor (TCGA): 1.9" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 5 "naive B-cell: 62.1" "Lineage enriched" "Detected in single" 622 "B-cells: 62.1" "Cancer enriched" "Detected in some" 6 "Leukemia: 8.2" "Breast - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Prostate - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "unprognostic (5.27e-1)" "unprognostic (4.03e-2)" IGHD3-9 "DXP1, IGHD39" ENSG00000211924 "Immunoglobulin heavy diversity 3-9" 14 105904681-105904711 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 11.2;stomach 1: 4.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 213 "memory B-cell: 9.3;naive B-cell: 33.3" "Lineage enriched" "Detected in single" 333 "B-cells: 33.3" "Cancer enriched" "Detected in single" 8 "Leukemia: 6.6" "Breast - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "unprognostic (1.56e-1)" "unprognostic (6.25e-2)" "unprognostic (2.40e-2)" "unprognostic (1.84e-1)" IGHD3OR15-3A "IGHD3/OR15-3A, IGHD3OR153A" ENSG00000282520 "Immunoglobulin heavy diversity 3/OR15-3A (non-functional)" 15 20005905-20005935 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 49: Hindbrain - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" IGHD3OR15-3B "IGHD3/OR15-3B, IGHD3OR153B" ENSG00000282089 "Immunoglobulin heavy diversity 3/OR15-3B (non-functional)" 15 21012559-21012589 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 49: Hindbrain - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" IGHD4-11 "DA1, IGHD411" ENSG00000232543 "Immunoglobulin heavy diversity 4-11 (non-functional)" 14 105903616-105903631 "Immunoglobulin genes, Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA IGHD4-17 IGHD417 ENSG00000227800 "Immunoglobulin heavy diversity 4-17" 14 105894508-105894523 "Immunoglobulin genes, Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Minor Salivary Gland - Plasma cells" NA NA IGHD4-23 IGHD423 ENSG00000227196 "Immunoglobulin heavy diversity 4-23 (non-functional)" 14 105884870-105884888 "Immunoglobulin genes, Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA IGHD4-4 "DA4, IGHD44" ENSG00000233655 "Immunoglobulin heavy diversity 4-4" 14 105913222-105913237 "Immunoglobulin genes, Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA IGHD4OR15-4A "IGHD4/OR15-4A, IGHD4OR154A" ENSG00000271317 "Immunoglobulin heavy diversity 4/OR15-4A (non-functional)" 15 20004797-20004815 "Immunoglobulin genes, Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA IGHD4OR15-4B "IGHD4/OR15-4B, IGHD4OR154B" ENSG00000270451 "Immunoglobulin heavy diversity 4/OR15-4B (non-functional)" 15 21011451-21011469 "Immunoglobulin genes, Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA IGHD5-12 "DK1, IGHD512" ENSG00000211921 "Immunoglobulin heavy diversity 5-12" 14 105902649-105902671 "Immunoglobulin genes, Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Minor Salivary Gland - Plasma cells" NA NA IGHD5-18 IGHD518 ENSG00000211915 "Immunoglobulin heavy diversity 5-18" 14 105893542-105893561 "Immunoglobulin genes, Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA IGHD5-24 IGHD524 ENSG00000211909 "Immunoglobulin heavy diversity 5-24 (non-functional)" 14 105883903-105883922 "Immunoglobulin genes, Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA IGHD5-5 "DK4, IGHD55" ENSG00000211928 "Immunoglobulin heavy diversity 5-5" 14 105912257-105912276 "Immunoglobulin genes, Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA IGHD5OR15-5A "IGHD5/OR15-5A, IGHD5OR155A" ENSG00000270961 "Immunoglobulin heavy diversity 5/OR15-5A (non-functional)" 15 20003840-20003862 "Immunoglobulin genes, Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA IGHD5OR15-5B "IGHD5/OR15-5B, IGHD5OR155B" ENSG00000270824 "Immunoglobulin heavy diversity 5/OR15-5B (non-functional)" 15 21010494-21010516 "Immunoglobulin genes, Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA IGHD6-13 "DN1, IGHD613" ENSG00000211920 "Immunoglobulin heavy diversity 6-13" 14 105901142-105901162 "Immunoglobulin genes, Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA IGHD6-19 IGHD619 ENSG00000211914 "Immunoglobulin heavy diversity 6-19" 14 105891699-105891719 "Immunoglobulin genes, Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Minor Salivary Gland - Plasma cells" NA NA IGHD6-25 IGHD625 ENSG00000225825 "Immunoglobulin heavy diversity 6-25" 14 105881539-105881556 "Immunoglobulin genes, Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA IGHD6-6 "D(N4), IGHD66" ENSG00000228131 "Immunoglobulin heavy diversity 6-6" 14 105910410-105910427 "Immunoglobulin genes, Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA IGHD7-27 "DHQ52, IGHD727" ENSG00000236597 "Immunoglobulin heavy diversity 7-27" 14 105865551-105865561 "Immunoglobulin genes, Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA IGHE ENSG00000211891 "Immunoglobulin heavy constant epsilon" P01854 14 105597691-105601728 "Immunoglobulin genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity, Inflammatory response" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 1.7;lymphoid tissue: 4.4;thyroid gland: 2.5" "Group enriched" "Detected in some" 4 "Epididymal principal cells: 8.4;Oocytes: 23.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 29 "Myeloma: 138.8" "Minor Salivary Gland - Plasma cells, Skin - Sebaceous gland cells" "Not detected" "Not detected" "Not detected" "Not detected" "Immunoglobulin genes" Immunity NA NA "Cluster 5: Spleen - Immune response" "Cluster 20: Myeloma - Immune response" "Cluster 41: Oocytes - Oogenesis" IGHG1 ENSG00000211896 "Immunoglobulin heavy constant gamma 1 (G1m marker)" P01857 14 105736343-105743071 "Disease related genes, FDA approved drug targets, Immunoglobulin genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "lymphoid tissue: 10950.9;urinary bladder: 3756.3" "Cell type enriched" "Detected in some" 47 "Plasma cells: 2491.1" "Cell type enriched" "Detected in some" 10 "leukocyte: 12.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 6 "memory B-cell: 768.6" "Lineage enriched" "Detected in many" 122 "B-cells: 768.6" "Cancer enriched" "Detected in some" 8 "Myeloma: 1184.5" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "HPA001245, CAB008642" Supported "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 67: Plasma cells - Plasma cell differentiation" 36 "CAB008642: , HPA001245: " "unprognostic (3.44e-3)" "unprognostic (4.44e-3)" "unprognostic (2.33e-3)" "unprognostic (1.17e-1)" "unprognostic (3.60e-1)" "unprognostic (2.17e-3)" "unprognostic (1.87e-1)" "potential prognostic favorable (2.46e-4)" "unprognostic (1.14e-1)" "potential prognostic unfavorable (3.50e-4)" "unprognostic (9.46e-2)" "unprognostic (3.38e-3)" "unprognostic (3.58e-2)" "unprognostic (5.34e-2)" "unprognostic (2.12e-2)" "unprognostic (1.55e-1)" "unprognostic (1.66e-1)" "unprognostic (1.26e-2)" "unprognostic (2.14e-2)" "unprognostic (7.20e-2)" "unprognostic (4.54e-3)" "unprognostic (1.19e-1)" "unprognostic (6.07e-2)" "unprognostic (2.70e-3)" "unprognostic (4.48e-2)" "unprognostic (2.77e-1)" "unprognostic (3.97e-1)" "unprognostic (1.09e-1)" "unprognostic (2.65e-2)" IGHG2 ENSG00000211893 "Immunoglobulin heavy constant gamma 2 (G2m marker)" P01859 14 105639559-105644790 "FDA approved drug targets, Immunoglobulin genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "lymphoid tissue: 4045.9" "Cell type enriched" "Detected in some" 32 "Plasma cells: 1009.8" "Cell type enriched" "Detected in single" 11 "leukocyte: 4.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 460 "memory B-cell: 344.6;naive B-cell: 128.5" "Lineage enriched" "Detected in single" 670 "B-cells: 344.6" "Group enriched" "Detected in some" 9 "lymphoma: 19.2;Myeloma: 54.1" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" HPA001245 Approved "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 5: Spleen - Immune response" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 44: Plasma cells - Antibody production & secretion" 28 "HPA001245: " "unprognostic (9.17e-3)" "unprognostic (1.01e-1)" "potential prognostic favorable (3.62e-5)" "unprognostic (3.20e-1)" "unprognostic (8.89e-2)" "unprognostic (2.85e-3)" "unprognostic (1.78e-3)" "potential prognostic favorable (8.19e-5)" "unprognostic (2.87e-2)" "potential prognostic unfavorable (3.60e-4)" "unprognostic (6.22e-3)" "unprognostic (1.44e-2)" "unprognostic (4.10e-2)" "unprognostic (3.87e-2)" "unprognostic (1.22e-1)" "unprognostic (5.76e-2)" "unprognostic (2.21e-2)" "unprognostic (6.18e-2)" "unprognostic (3.02e-1)" "unprognostic (4.52e-1)" "unprognostic (1.15e-2)" "unprognostic (2.27e-2)" "unprognostic (8.39e-2)" "unprognostic (3.90e-3)" "unprognostic (8.31e-2)" "unprognostic (2.96e-1)" "unprognostic (3.81e-1)" "unprognostic (1.24e-1)" "unprognostic (4.65e-2)" IGHG3 ENSG00000211897 "Immunoglobulin heavy constant gamma 3 (G3m marker)" 14 105764503-105771405 "Immunoglobulin genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 7 "lymphoid tissue: 1227.4" "Cell type enriched" "Detected in some" 58 "Plasma cells: 329.1" "Cell type enriched" "Detected in single" 19 "leukocyte: 5.3" "Cancer enhanced" "Detected in all" "Lung Squamous Cell Carcinoma (TCGA): 1536.4" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 416 "memory B-cell: 211.7;naive B-cell: 65.4" "Lineage enriched" "Detected in single" 636 "B-cells: 211.7" "Cancer enriched" "Detected in some" 4 "lymphoma: 97.5" "Adipose subcutaneous - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 8: Immune cells - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 78: Plasma cells - Antibody production & ER-stress response" "potential prognostic favorable (1.38e-4)" "unprognostic (5.25e-3)" "unprognostic (1.26e-3)" "unprognostic (1.28e-1)" "unprognostic (7.20e-2)" "unprognostic (7.06e-3)" "unprognostic (1.96e-2)" "potential prognostic favorable (7.56e-5)" "unprognostic (1.14e-1)" "potential prognostic unfavorable (2.84e-4)" "unprognostic (1.35e-2)" "unprognostic (4.08e-3)" "unprognostic (8.51e-3)" "unprognostic (3.18e-2)" "unprognostic (3.43e-1)" "unprognostic (6.57e-2)" "unprognostic (1.03e-1)" "unprognostic (3.74e-2)" "unprognostic (3.80e-2)" "unprognostic (2.15e-1)" "unprognostic (9.19e-3)" "unprognostic (1.46e-1)" "unprognostic (1.78e-1)" "unprognostic (2.92e-2)" "unprognostic (3.34e-2)" "unprognostic (5.43e-2)" "unprognostic (2.00e-1)" "unprognostic (8.94e-2)" "unprognostic (1.90e-1)" IGHG4 ENSG00000211892 "Immunoglobulin heavy constant gamma 4 (G4m marker)" P01861 14 105620506-105626066 "FDA approved drug targets, Immunoglobulin genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 2337.9" "Cell type enriched" "Detected in some" 7 "Plasma cells: 120.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 457 "memory B-cell: 123.0;naive B-cell: 74.3" "Lineage enriched" "Detected in single" 569 "B-cells: 123.0" "Group enriched" "Detected in some" 43 "lymphoma: 133.6;Myeloma: 34.1" "Adipose subcutaneous - Plasma cells, Adipose visceral - Mesothelial cells, Adrenal gland - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Lung - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells" HPA001245 Approved "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 44: Plasma cells - Antibody production & secretion" 20 "HPA001245: " "unprognostic (3.88e-2)" "unprognostic (4.37e-3)" "unprognostic (5.42e-2)" "unprognostic (1.05e-1)" "unprognostic (4.47e-1)" "unprognostic (3.18e-3)" "unprognostic (5.65e-2)" "potential prognostic favorable (6.88e-4)" "unprognostic (2.10e-1)" "unprognostic (1.11e-3)" "unprognostic (1.31e-2)" "potential prognostic unfavorable (6.78e-5)" "unprognostic (3.95e-1)" "unprognostic (6.49e-3)" "unprognostic (9.67e-2)" "unprognostic (2.31e-1)" "unprognostic (1.34e-1)" "unprognostic (1.36e-1)" "unprognostic (2.57e-1)" "unprognostic (4.76e-2)" "unprognostic (7.83e-3)" "unprognostic (1.12e-1)" "unprognostic (5.38e-2)" "potential prognostic favorable (4.51e-6)" "unprognostic (2.15e-1)" "unprognostic (1.12e-1)" "unprognostic (1.23e-1)" "unprognostic (6.43e-2)" "unprognostic (3.77e-1)" IGHJ1 ENSG00000211905 "Immunoglobulin heavy joining 1" A0A0C4DH62 14 105865407-105865458 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 4 "intestine: 344.0;lymphoid tissue: 393.3;salivary gland: 110.6;stomach 1: 245.5" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Stomach Adenocarcinoma (TCGA): 95.7" "Region enhanced" "Detected in some" "cerebral cortex: 3.6" "Group enriched" "Detected in some" 72 "memory B-cell: 277.0;naive B-cell: 181.7;plasmacytoid DC: 99.3" "Group enriched" "Detected in many" 73 "B-cells: 277.0;dendritic cells: 99.3" "Group enriched" "Detected in some" 6 "Leukemia: 3.4;lymphoma: 2.4;Myeloma: 1.5" "Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "unprognostic (5.83e-1)" "potential prognostic favorable (1.35e-4)" "unprognostic (1.14e-1)" "unprognostic (4.55e-2)" "unprognostic (8.53e-2)" "unprognostic (4.20e-2)" "potential prognostic favorable (9.88e-4)" "unprognostic (4.51e-3)" "unprognostic (2.15e-1)" "unprognostic (1.76e-1)" "unprognostic (1.31e-1)" "unprognostic (3.05e-2)" "unprognostic (4.74e-3)" "unprognostic (1.49e-1)" "unprognostic (1.38e-1)" "unprognostic (2.53e-2)" "unprognostic (3.21e-1)" "unprognostic (4.10e-2)" "unprognostic (3.25e-3)" "unprognostic (1.53e-1)" "unprognostic (7.36e-1)" "unprognostic (4.20e-2)" "unprognostic (1.43e-1)" "unprognostic (3.14e-1)" "unprognostic (4.76e-2)" IGHJ2 ENSG00000211904 "Immunoglobulin heavy joining 2" 14 105865199-105865250 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 148.3;lymphoid tissue: 152.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "medulla oblongata: 7.4" "Group enriched" "Detected in some" 18 "MAIT T-cell: 49.4;naive B-cell: 13.1" "Group enriched" "Detected in many" 46 "B-cells: 13.1;T-cells: 49.4" "Cancer enriched" "Detected in some" 16 "Myeloma: 566.2" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "unprognostic (3.21e-1)" "unprognostic (2.29e-2)" "unprognostic (1.60e-1)" "unprognostic (2.99e-1)" "unprognostic (5.24e-2)" "unprognostic (1.34e-1)" "unprognostic (7.49e-2)" "unprognostic (2.60e-1)" "unprognostic (2.46e-1)" "unprognostic (3.39e-1)" "unprognostic (1.15e-1)" "unprognostic (3.66e-1)" "unprognostic (2.00e-1)" "unprognostic (2.10e-1)" "unprognostic (1.98e-1)" "unprognostic (5.61e-1)" "unprognostic (1.06e-1)" "unprognostic (5.12e-3)" "unprognostic (1.12e-3)" "unprognostic (1.06e-1)" "unprognostic (8.57e-2)" "unprognostic (1.26e-1)" "unprognostic (2.85e-1)" IGHJ3 ENSG00000242887 "Immunoglobulin heavy joining 3" 14 105864587-105864635 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "esophagus: 34.2;pancreas: 58.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 8 "basophil: 9.0;naive B-cell: 35.9" "Group enriched" "Detected in many" 8 "B-cells: 35.9;granulocytes: 9.0" "Cancer enriched" "Detected in some" 7 "Myeloma: 88.4" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 8: Pancreas - Proteolysis" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "unprognostic (2.55e-1)" "unprognostic (4.20e-1)" "unprognostic (1.28e-1)" "unprognostic (1.60e-1)" "unprognostic (2.10e-1)" "unprognostic (4.12e-1)" "unprognostic (5.55e-1)" "unprognostic (7.55e-3)" "unprognostic (9.76e-2)" "unprognostic (6.98e-1)" "unprognostic (3.40e-1)" "unprognostic (4.10e-1)" "unprognostic (2.05e-1)" "unprognostic (4.29e-1)" "unprognostic (4.06e-1)" "unprognostic (3.95e-1)" "unprognostic (1.32e-1)" "unprognostic (4.55e-1)" "unprognostic (7.50e-2)" "unprognostic (2.24e-1)" "unprognostic (2.21e-1)" "unprognostic (3.51e-1)" "unprognostic (3.56e-1)" "unprognostic (3.90e-2)" "unprognostic (2.35e-1)" IGHJ4 ENSG00000240041 "Immunoglobulin heavy joining 4" 14 105864215-105864260 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 7 "esophagus: 196.2;intestine: 232.8;stomach 1: 424.7;urinary bladder: 555.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "midbrain: 65.3" "Group enriched" "Detected in many" 186 "memory B-cell: 5988.8;naive B-cell: 2632.7" "Lineage enriched" "Detected in all" 258 "B-cells: 5988.8" "Group enriched" "Detected in some" 7 "lymphoma: 629.5;Myeloma: 2140.2" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 17: Intestine - Digestion" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 51: Myeloma - Immunoglobulins" "unprognostic (4.40e-2)" "unprognostic (1.46e-1)" "unprognostic (9.56e-2)" "unprognostic (9.55e-3)" "unprognostic (2.36e-2)" "unprognostic (1.72e-2)" "unprognostic (1.97e-1)" "unprognostic (1.39e-1)" "unprognostic (5.99e-1)" "unprognostic (1.63e-1)" "unprognostic (7.21e-2)" "unprognostic (1.30e-1)" "unprognostic (1.24e-1)" "unprognostic (9.34e-2)" "unprognostic (1.37e-1)" "unprognostic (2.57e-1)" "unprognostic (4.05e-2)" "unprognostic (2.11e-1)" "unprognostic (2.13e-2)" "unprognostic (2.63e-1)" "unprognostic (3.82e-1)" "unprognostic (1.03e-1)" "unprognostic (4.83e-1)" "unprognostic (5.66e-2)" "unprognostic (5.72e-1)" "unprognostic (1.34e-1)" "unprognostic (2.32e-1)" IGHJ5 ENSG00000242472 "Immunoglobulin heavy joining 5" 14 105863814-105863862 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "breast: 69.1;intestine: 109.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 261 "memory B-cell: 1076.2" "Lineage enriched" "Detected in many" 261 "B-cells: 1076.2" "Group enriched" "Detected in some" 5 "lymphoma: 149.7;Myeloma: 241.1" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 17: Intestine - Digestion" "Cluster 7: Non-specific - Ribosome" "Cluster 51: Myeloma - Immunoglobulins" "unprognostic (3.83e-1)" "unprognostic (3.31e-2)" "unprognostic (1.79e-1)" "unprognostic (2.17e-1)" "unprognostic (3.92e-1)" "unprognostic (1.53e-1)" "unprognostic (1.18e-1)" "unprognostic (5.89e-2)" "unprognostic (9.01e-1)" "unprognostic (1.51e-1)" "unprognostic (2.98e-1)" "unprognostic (5.35e-1)" "unprognostic (8.32e-2)" "unprognostic (5.42e-3)" "unprognostic (5.95e-1)" "unprognostic (1.22e-1)" "unprognostic (2.87e-1)" "unprognostic (6.30e-2)" "unprognostic (6.59e-2)" "unprognostic (1.23e-1)" "potential prognostic favorable (4.54e-4)" "unprognostic (5.24e-2)" "unprognostic (2.58e-1)" "unprognostic (1.02e-2)" "unprognostic (2.38e-1)" "unprognostic (6.93e-2)" "unprognostic (3.00e-1)" IGHJ6 ENSG00000211900 "Immunoglobulin heavy joining 6" 14 105863198-105863258 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "cervix: 128.7;intestine: 37.6;lung: 42.5;lymphoid tissue: 59.3;testis: 142.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 14 "memory B-cell: 323.3;naive B-cell: 111.0" "Lineage enriched" "Detected in many" 22 "B-cells: 323.3" "Cancer enriched" "Detected in some" 7 "lymphoma: 42.7" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 61: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "unprognostic (1.13e-1)" "unprognostic (7.77e-2)" "unprognostic (7.62e-2)" "unprognostic (7.30e-2)" "unprognostic (3.32e-2)" "unprognostic (1.77e-1)" "unprognostic (4.83e-1)" "unprognostic (8.22e-2)" "unprognostic (9.57e-2)" "unprognostic (2.78e-1)" "unprognostic (1.27e-1)" "unprognostic (1.11e-1)" "unprognostic (1.31e-2)" "unprognostic (6.61e-2)" "unprognostic (5.39e-1)" "unprognostic (1.07e-1)" "unprognostic (3.11e-1)" "unprognostic (1.07e-2)" "unprognostic (2.93e-1)" "unprognostic (1.07e-2)" "unprognostic (3.43e-1)" "unprognostic (7.07e-1)" IGHM ENSG00000211899 "Immunoglobulin heavy constant mu" P01871 14 105851705-105856218 "Disease related genes, Immunoglobulin genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 1239.2;lymphoid tissue: 3964.5" "Group enriched" "Detected in some" 8 "B-cells: 476.0;Plasma cells: 485.8" "Cell type enriched" "Detected in single" 110 "leukocyte: 69.0" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 760.7" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 16 "memory B-cell: 4293.6;naive B-cell: 6750.1" "Lineage enriched" "Detected in all" 19 "B-cells: 6750.1" "Cancer enriched" "Detected in some" 4 "lymphoma: 1665.3" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB008643 Uncertain "Immunoglobulin genes" Immunity NA NA "Cluster 18: Non-specific - Translation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 8: Immune cells - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 67: Plasma cells - Plasma cell differentiation" "CAB008643: " "potential prognostic favorable (4.88e-4)" "potential prognostic favorable (7.49e-4)" "potential prognostic favorable (3.70e-4)" "unprognostic (2.15e-2)" "unprognostic (1.39e-1)" "unprognostic (4.62e-2)" "unprognostic (3.09e-3)" "potential prognostic favorable (5.16e-6)" "unprognostic (4.67e-1)" "unprognostic (4.94e-2)" "unprognostic (1.08e-1)" "unprognostic (1.23e-2)" "unprognostic (3.30e-3)" "unprognostic (2.72e-3)" "unprognostic (3.44e-2)" "unprognostic (4.97e-2)" "unprognostic (2.13e-2)" "unprognostic (2.17e-2)" "unprognostic (4.62e-2)" "unprognostic (1.86e-2)" "unprognostic (2.90e-2)" "unprognostic (8.37e-2)" "unprognostic (1.48e-2)" "unprognostic (2.48e-1)" "unprognostic (3.81e-2)" "unprognostic (8.32e-2)" "unprognostic (3.82e-1)" "unprognostic (4.86e-2)" "unprognostic (5.96e-2)" IGHMBP2 "CATF1, CMT2S, HCSA, HMN6, SMARD1, SMUBP2, ZFAND7" ENSG00000132740 "Immunoglobulin mu DNA binding protein 2" P38935 11 68903863-68940602 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding, Helicase, Hydrolase, Ribonucleoprotein, RNA-binding, tRNA-binding" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 89.3;Late primary spermatocytes: 119.7;Late spermatids: 60.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058367, HPA060994" Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 67: Testis - Mixed function" "Cluster 14: Neurons - Synaptic function" "Cluster 24: Non-specific - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 3 Nucleoplasm "Nuclear bodies, Cytosol" "HPA058367: , HPA060994: " "unprognostic (3.79e-2)" "unprognostic (5.78e-2)" "unprognostic (3.39e-2)" "unprognostic (5.35e-2)" "unprognostic (3.57e-2)" "unprognostic (3.96e-1)" "unprognostic (2.56e-1)" "unprognostic (2.35e-3)" "unprognostic (1.64e-2)" "unprognostic (3.04e-1)" "potential prognostic favorable (5.28e-7)" "unprognostic (2.80e-1)" "unprognostic (7.15e-2)" "unprognostic (1.05e-1)" "unprognostic (1.91e-1)" "unprognostic (2.31e-2)" "unprognostic (5.05e-2)" "unprognostic (1.68e-2)" "unprognostic (2.76e-1)" "unprognostic (1.01e-2)" "unprognostic (3.82e-2)" "unprognostic (4.25e-2)" "unprognostic (1.21e-2)" "unprognostic (2.28e-1)" "unprognostic (3.99e-2)" "unprognostic (5.47e-3)" "unprognostic (6.57e-2)" "unprognostic (8.16e-2)" "unprognostic (2.93e-1)" "unprognostic (2.02e-1)" "unprognostic (1.90e-1)" IGHV1-18 ENSG00000211945 "Immunoglobulin heavy variable 1-18" A0A0C4DH31 14 106184901-106185394 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 231.7;lymphoid tissue: 455.7;salivary gland: 235.9" "Cell type enriched" "Detected in some" 5 "Plasma cells: 30.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in some" 21 "memory B-cell: 73.4" "Lineage enriched" "Detected in many" 21 "B-cells: 73.4" "Cancer enriched" "Detected in single" 121 "lymphoma: 41.4" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 5: Spleen - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 44: Plasma cells - Antibody production & secretion" "unprognostic (1.02e-1)" "unprognostic (4.33e-1)" "unprognostic (6.03e-2)" "unprognostic (1.01e-2)" "unprognostic (1.10e-1)" "unprognostic (1.21e-1)" "unprognostic (6.33e-2)" "unprognostic (4.37e-1)" "unprognostic (2.75e-2)" "unprognostic (5.26e-1)" "unprognostic (5.05e-2)" "unprognostic (4.51e-1)" "unprognostic (1.28e-2)" "unprognostic (1.30e-1)" "unprognostic (3.13e-2)" "unprognostic (5.52e-1)" "unprognostic (2.78e-1)" "unprognostic (2.71e-1)" "unprognostic (9.23e-3)" "unprognostic (2.44e-1)" "unprognostic (2.09e-1)" "unprognostic (4.58e-2)" "unprognostic (1.40e-1)" "unprognostic (3.33e-1)" "unprognostic (1.98e-1)" "unprognostic (6.19e-2)" "unprognostic (3.65e-1)" IGHV1-2 V35 ENSG00000211934 "Immunoglobulin heavy variable 1-2" P23083 14 105986582-105987083 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 432.4;lymphoid tissue: 1081.5" "Cell type enriched" "Detected in some" 6 "Plasma cells: 16.9" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 51 "memory B-cell: 286.5;naive B-cell: 348.4" "Lineage enriched" "Detected in many" 56 "B-cells: 348.4" "Cancer enriched" "Detected in some" 8 "Myeloma: 578.3" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 18: Non-specific - Translation" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 20: Myeloma - Immune response" "Cluster 78: Plasma cells - Antibody production & ER-stress response" "unprognostic (5.52e-2)" "potential prognostic favorable (2.68e-4)" "unprognostic (1.29e-3)" "unprognostic (1.92e-1)" "unprognostic (3.75e-1)" "unprognostic (1.37e-2)" "unprognostic (7.61e-2)" "potential prognostic favorable (9.19e-5)" "unprognostic (3.00e-1)" "unprognostic (7.08e-2)" "unprognostic (2.57e-1)" "unprognostic (5.07e-3)" "unprognostic (3.59e-1)" "unprognostic (5.45e-2)" "unprognostic (2.67e-3)" "unprognostic (3.40e-1)" "unprognostic (1.26e-1)" "unprognostic (1.52e-1)" "unprognostic (2.25e-1)" "unprognostic (2.31e-1)" "unprognostic (1.82e-1)" "unprognostic (5.30e-2)" "unprognostic (1.22e-2)" "unprognostic (1.54e-1)" "unprognostic (5.76e-2)" "unprognostic (1.01e-2)" "unprognostic (2.70e-1)" "unprognostic (3.13e-1)" "unprognostic (8.03e-2)" IGHV1-24 ENSG00000211950 "Immunoglobulin heavy variable 1-24" A0A0C4DH33 14 106276548-106277043 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 180.1;salivary gland: 71.8" "Cell type enhanced" "Detected in some" "Early spermatids: 2.3;Late primary spermatocytes: 2.0;Late spermatids: 1.0;Parietal cells: 1.8;Plasma cells: 7.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 223.7" "Group enriched" "Detected in some" 4 "cerebral cortex: 1.3;medulla oblongata: 2.7" "Immune cell enhanced" "Detected in single" "naive B-cell: 2.8" "Lineage enriched" "Detected in single" 9 "B-cells: 2.8" "Cancer enriched" "Detected in single" 6 "Leukemia: 1.2" "Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 59: Leukemia - T-cell receptor" "Cluster 67: Plasma cells - Plasma cell differentiation" "unprognostic (1.38e-2)" "unprognostic (7.32e-3)" "potential prognostic favorable (8.04e-4)" "unprognostic (7.76e-2)" "unprognostic (1.84e-1)" "unprognostic (6.38e-3)" "unprognostic (7.09e-3)" "unprognostic (3.58e-1)" "unprognostic (7.53e-3)" "unprognostic (3.31e-2)" "unprognostic (3.10e-2)" "unprognostic (3.33e-2)" "unprognostic (5.08e-2)" "unprognostic (1.64e-1)" "unprognostic (1.61e-1)" "unprognostic (3.57e-1)" "unprognostic (8.36e-3)" "unprognostic (1.37e-1)" "unprognostic (5.80e-2)" "unprognostic (1.66e-1)" "unprognostic (4.33e-1)" "unprognostic (3.76e-1)" "unprognostic (2.49e-1)" "unprognostic (4.37e-1)" "unprognostic (2.49e-1)" "unprognostic (3.85e-1)" IGHV1-3 VI-3B ENSG00000211935 "Immunoglobulin heavy variable 1-3" A0A0C4DH29 14 106005095-106005574 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 208.7;lymphoid tissue: 585.6" "Group enriched" "Detected in some" 4 "Plasma cells: 5.4;Platelets: 2.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 7 "memory B-cell: 52.9;naive B-cell: 27.9" "Lineage enriched" "Detected in many" 9 "B-cells: 52.9" "Cancer enriched" "Detected in some" 30 "Myeloma: 733.0" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 78: Plasma cells - Antibody production & ER-stress response" "unprognostic (2.80e-2)" "unprognostic (9.10e-3)" "unprognostic (2.31e-2)" "unprognostic (5.28e-2)" "unprognostic (1.82e-1)" "unprognostic (3.61e-2)" "unprognostic (2.22e-1)" "unprognostic (1.09e-3)" "unprognostic (9.34e-2)" "unprognostic (4.10e-3)" "unprognostic (1.16e-3)" "unprognostic (6.26e-2)" "unprognostic (1.37e-2)" "unprognostic (6.55e-2)" "potential prognostic unfavorable (5.59e-5)" "unprognostic (9.79e-2)" "unprognostic (6.01e-1)" "unprognostic (2.16e-1)" "unprognostic (6.07e-2)" "unprognostic (1.87e-1)" "unprognostic (6.38e-2)" "unprognostic (7.32e-2)" "unprognostic (7.11e-3)" "unprognostic (1.44e-1)" "unprognostic (2.96e-2)" "unprognostic (1.51e-1)" "unprognostic (2.06e-1)" IGHV1-45 ENSG00000211961 "Immunoglobulin heavy variable 1-45" A0A0A0MS14 14 106506996-106507491 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 17.5;lymphoid tissue: 28.2;salivary gland: 10.9;stomach 1: 16.4" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Lung Adenocarcinoma (TCGA): 6.4;Lung Squamous Cell Carcinoma (TCGA): 20.4" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in single" "Gallbladder cancer: 1.1" "Adipose visceral - Plasma cells, Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 24: Non-specific - Transcription" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 44: Plasma cells - Antibody production & secretion" "unprognostic (1.47e-3)" "unprognostic (2.98e-2)" "unprognostic (2.12e-3)" "unprognostic (1.48e-1)" "unprognostic (1.38e-1)" "unprognostic (1.04e-1)" "unprognostic (6.05e-2)" "unprognostic (9.05e-2)" "unprognostic (3.30e-2)" "unprognostic (1.29e-1)" "unprognostic (4.81e-3)" "unprognostic (2.28e-1)" IGHV1-46 ENSG00000211962 "Immunoglobulin heavy variable 1-46" P01743 14 106511117-106511856 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 70.3;lymphoid tissue: 117.9;salivary gland: 65.7" "Group enriched" "Detected in some" 4 "Gastric chief cells: 4.4;Plasma cells: 10.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 17 "Myeloma: 18.8" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 5: Spleen - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 78: Plasma cells - Antibody production & ER-stress response" "unprognostic (2.96e-2)" "unprognostic (5.15e-3)" "unprognostic (1.52e-2)" "unprognostic (8.79e-3)" "unprognostic (6.53e-2)" "unprognostic (9.98e-2)" "unprognostic (8.08e-2)" "unprognostic (1.30e-2)" "unprognostic (1.42e-1)" "unprognostic (1.92e-3)" "unprognostic (1.96e-1)" "unprognostic (3.09e-1)" "unprognostic (7.67e-2)" "unprognostic (8.61e-2)" "unprognostic (2.88e-1)" "unprognostic (1.95e-1)" "unprognostic (4.11e-1)" "unprognostic (3.64e-1)" "unprognostic (9.30e-3)" "unprognostic (1.28e-1)" "unprognostic (9.83e-2)" "unprognostic (1.23e-1)" "unprognostic (1.60e-2)" "unprognostic (2.85e-1)" "unprognostic (9.81e-3)" "unprognostic (2.61e-1)" "unprognostic (1.40e-1)" IGHV1-58 ENSG00000211968 "Immunoglobulin heavy variable 1-58" A0A0C4DH39 14 106622357-106622855 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "urinary bladder: 192.5" "Cell type enhanced" "Detected in some" "Gastric chief cells: 1.1;Plasma cells: 2.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 49 "memory B-cell: 8.7;naive B-cell: 12.8" "Lineage enriched" "Detected in single" 58 "B-cells: 12.8" "Not detected" "Not detected" "Adipose visceral - Plasma cells, Breast - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 6: Leukemia - Signal transduction" "Cluster 78: Plasma cells - Antibody production & ER-stress response" "unprognostic (1.26e-1)" "unprognostic (8.91e-3)" "unprognostic (6.27e-2)" "unprognostic (1.24e-1)" "unprognostic (9.13e-2)" "potential prognostic favorable (3.45e-4)" "unprognostic (2.89e-3)" "unprognostic (5.33e-2)" "unprognostic (5.19e-3)" "unprognostic (2.15e-1)" "unprognostic (2.26e-2)" "unprognostic (1.40e-1)" "unprognostic (1.34e-1)" "unprognostic (1.63e-1)" "unprognostic (3.01e-2)" "unprognostic (2.66e-1)" "unprognostic (5.88e-3)" "unprognostic (1.86e-2)" "unprognostic (1.25e-1)" "unprognostic (1.73e-2)" "unprognostic (3.37e-1)" "unprognostic (1.58e-2)" "unprognostic (1.40e-1)" "unprognostic (6.53e-2)" "unprognostic (6.49e-1)" IGHV1-69 IGHV1-E ENSG00000211973 "Immunoglobulin heavy variable 1-69" P01742 14 106714684-106715181 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 129.8;lymphoid tissue: 158.0;urinary bladder: 155.9" "Cell type enriched" "Detected in single" 14 "Parietal cells: 1.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 18 "medulla oblongata: 4.9;pons: 5.9" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.5;plasmacytoid DC: 1.4" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in single" 9 "lymphoma: 2.7" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 5: Spleen - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 97: Non-specific - Cellular respiration" "unprognostic (1.41e-1)" "unprognostic (2.87e-1)" "unprognostic (5.06e-2)" "unprognostic (2.33e-2)" "unprognostic (9.69e-2)" "unprognostic (3.94e-1)" "unprognostic (2.83e-2)" "unprognostic (1.09e-1)" "unprognostic (6.01e-2)" "unprognostic (2.35e-3)" "unprognostic (1.26e-1)" "unprognostic (1.85e-1)" "unprognostic (2.24e-2)" "unprognostic (2.71e-1)" "unprognostic (1.59e-1)" "unprognostic (4.65e-2)" "unprognostic (2.61e-1)" "unprognostic (1.83e-1)" "unprognostic (5.39e-2)" "unprognostic (3.20e-1)" "unprognostic (2.42e-2)" "unprognostic (1.98e-1)" "unprognostic (4.30e-1)" "unprognostic (1.82e-1)" "unprognostic (3.05e-1)" "unprognostic (2.96e-1)" "unprognostic (1.10e-1)" IGHV1-69-2 IGHV1-F ENSG00000281990 "Immunoglobulin heavy variable 1-69-2" A0A0G2JMI3 14 106737110-106737547 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 20.7;lymphoid tissue: 44.6;salivary gland: 15.4" "Cell type enriched" "Detected in single" 13 "Plasma cells: 1.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "memory B-cell: 6.7;naive B-cell: 5.5" "Lineage enriched" "Detected in many" 6 "B-cells: 6.7" "Cancer enhanced" "Detected in single" "Leukemia: 1.4" "Breast - Plasma cells, Kidney - Plasma cells, Minor Salivary Gland - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 34: B-cells - Unknown function" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 6: Leukemia - Signal transduction" "Cluster 44: Plasma cells - Antibody production & secretion" "unprognostic (1.19e-1)" "unprognostic (5.19e-2)" "unprognostic (5.95e-2)" "unprognostic (2.41e-1)" "unprognostic (4.40e-1)" "unprognostic (4.82e-2)" "unprognostic (6.76e-3)" "unprognostic (1.81e-2)" "unprognostic (1.48e-1)" "unprognostic (3.32e-3)" "unprognostic (3.88e-1)" "unprognostic (7.35e-2)" "unprognostic (1.18e-1)" "unprognostic (2.06e-2)" "unprognostic (9.05e-2)" "unprognostic (1.18e-3)" "unprognostic (3.60e-1)" "unprognostic (2.68e-1)" "unprognostic (3.02e-2)" "unprognostic (2.57e-2)" "unprognostic (2.99e-1)" "unprognostic (6.75e-1)" IGHV1-69D ENSG00000280411 "Immunoglobulin heavy variable 1-69D" A0A0B4J2H0 14 106762092-106762588 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 2700.4;stomach 1: 929.5" "Cell type enriched" "Detected in some" 8 "Plasma cells: 25.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Lung Squamous Cell Carcinoma (TCGA): 576.9" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 225 "memory B-cell: 185.4;naive B-cell: 435.3" "Lineage enriched" "Detected in many" 316 "B-cells: 435.3" "Cancer enriched" "Detected in some" 8 "lymphoma: 278.1" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 67: Plasma cells - Plasma cell differentiation" "unprognostic (1.56e-2)" "unprognostic (1.21e-3)" "unprognostic (5.87e-2)" "unprognostic (1.09e-1)" "unprognostic (2.62e-1)" "unprognostic (2.38e-3)" "unprognostic (5.60e-2)" "unprognostic (2.92e-2)" "unprognostic (2.73e-2)" "unprognostic (1.19e-2)" "unprognostic (2.35e-3)" "unprognostic (3.62e-1)" "unprognostic (1.97e-1)" "unprognostic (2.34e-1)" "unprognostic (6.92e-2)" "unprognostic (1.58e-1)" "unprognostic (9.23e-3)" "unprognostic (4.18e-1)" "unprognostic (7.20e-2)" "unprognostic (5.97e-3)" "unprognostic (1.96e-2)" "unprognostic (1.37e-1)" "unprognostic (9.47e-2)" "unprognostic (1.73e-1)" "unprognostic (2.85e-1)" "unprognostic (5.50e-1)" IGHV1OR15-1 IGHV1/OR15-1 ENSG00000270505 "Immunoglobulin heavy variable 1/OR15-1 (non-functional)" 15 22160431-22160868 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 73.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "memory B-cell: 94.7;naive B-cell: 112.0" "Group enriched" "Detected in many" 18 "B-cells: 112.0;T-cells: 61.1" "Group enriched" "Detected in some" 23 "Leukemia: 7.2;lymphoma: 3.2;Myeloma: 3.5" "Breast - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "potential prognostic favorable (7.49e-4)" "unprognostic (5.65e-2)" "unprognostic (1.89e-1)" "unprognostic (2.57e-2)" "unprognostic (3.73e-2)" "potential prognostic favorable (1.15e-4)" "unprognostic (1.77e-2)" "unprognostic (8.41e-2)" "unprognostic (1.20e-2)" "unprognostic (3.47e-1)" "unprognostic (2.03e-2)" "unprognostic (1.16e-1)" "unprognostic (1.09e-1)" "unprognostic (2.03e-1)" "unprognostic (7.18e-2)" "unprognostic (1.96e-1)" "unprognostic (7.79e-2)" "unprognostic (3.66e-1)" "unprognostic (9.38e-2)" IGHV1OR15-9 "IGHV1/OR15-9, IGHV1OR159, VSIG7" ENSG00000188403 "Immunoglobulin heavy variable 1/OR15-9 (non-functional)" 15 19964666-19965101 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 13 "breast: 3.8;intestine: 8.0;lymphoid tissue: 8.1;stomach 1: 7.8" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Lung Adenocarcinoma (TCGA): 1.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" NA NA "Cluster 34: Lymphoid tissue - Adaptive immune response" "unprognostic (3.48e-2)" "unprognostic (1.37e-2)" "unprognostic (1.50e-1)" "unprognostic (1.02e-1)" "unprognostic (7.07e-3)" "unprognostic (1.87e-1)" "unprognostic (2.36e-1)" IGHV1OR21-1 IGHV1/OR21-1 ENSG00000277282 "Immunoglobulin heavy variable 1/OR21-1 (non-functional)" 21 10649400-10649835 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "intestine: 3.0;lymphoid tissue: 5.9;stomach 1: 3.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 14 "memory B-cell: 2.0;naive B-cell: 1.7" "Lineage enriched" "Detected in single" 15 "B-cells: 2.0" "Not detected" "Not detected" "Breast - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" NA NA "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 20: Myeloma - Immune response" "Cluster 44: Plasma cells - Antibody production & secretion" "unprognostic (5.74e-1)" "unprognostic (4.40e-3)" "unprognostic (2.32e-3)" "unprognostic (2.70e-3)" "unprognostic (1.18e-1)" "unprognostic (4.57e-2)" "unprognostic (9.92e-2)" "unprognostic (2.99e-1)" "unprognostic (2.48e-1)" "unprognostic (3.26e-1)" IGHV2-26 ENSG00000211951 "Immunoglobulin heavy variable 2-26" A0A0B4J1V2 14 106301396-106301862 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 120.9;lymphoid tissue: 91.9;urinary bladder: 214.8" "Cell type enriched" "Detected in single" 8 "Plasma cells: 1.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in some" 14 "memory B-cell: 14.1" "Lineage enriched" "Detected in single" 141 "B-cells: 14.1" "Not detected" "Not detected" "Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 67: Plasma cells - Plasma cell differentiation" "unprognostic (1.35e-1)" "unprognostic (3.88e-3)" "unprognostic (4.71e-2)" "unprognostic (5.46e-2)" "unprognostic (6.47e-2)" "unprognostic (1.02e-1)" "unprognostic (5.27e-2)" "unprognostic (3.00e-2)" "unprognostic (1.13e-1)" "unprognostic (2.98e-3)" "unprognostic (1.37e-1)" "unprognostic (1.09e-1)" "unprognostic (1.67e-1)" "unprognostic (6.04e-2)" "unprognostic (3.08e-1)" "unprognostic (9.73e-2)" "unprognostic (3.68e-1)" "unprognostic (1.71e-2)" "unprognostic (2.19e-2)" "unprognostic (3.68e-1)" "unprognostic (9.93e-2)" "unprognostic (1.10e-1)" "unprognostic (1.67e-1)" "unprognostic (7.33e-2)" "unprognostic (8.04e-2)" "unprognostic (3.53e-1)" "unprognostic (2.98e-2)" IGHV2-5 ENSG00000211937 "Immunoglobulin heavy variable 2-5" P01817 14 106037902-106038365 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 435.1;lymphoid tissue: 1331.1;stomach 1: 665.2" "Cell type enhanced" "Detected in some" "Foveolar cells: 1.4;Gastric chief cells: 6.6;Mucous neck cells: 2.8;Parietal cells: 8.8;Plasma cells: 14.7" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 22 "memory B-cell: 67.0;naive B-cell: 67.6" "Lineage enriched" "Detected in many" 22 "B-cells: 67.6" "Cancer enriched" "Detected in some" 32 "Myeloma: 1988.3" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 78: Plasma cells - Antibody production & ER-stress response" "unprognostic (4.17e-3)" "unprognostic (4.11e-3)" "unprognostic (2.76e-2)" "unprognostic (7.80e-2)" "unprognostic (1.86e-1)" "unprognostic (1.57e-3)" "unprognostic (4.46e-1)" "potential prognostic favorable (2.14e-4)" "unprognostic (1.56e-2)" "unprognostic (3.87e-2)" "unprognostic (3.31e-2)" "unprognostic (2.47e-3)" "unprognostic (2.57e-2)" "unprognostic (7.08e-2)" "unprognostic (6.40e-2)" "unprognostic (1.96e-2)" "unprognostic (2.05e-1)" "unprognostic (2.39e-1)" "unprognostic (2.05e-1)" "unprognostic (2.84e-1)" "unprognostic (8.13e-3)" "unprognostic (8.19e-2)" "unprognostic (6.26e-2)" "unprognostic (1.63e-1)" "unprognostic (3.02e-1)" "unprognostic (2.29e-2)" "unprognostic (1.58e-1)" "unprognostic (1.96e-1)" "unprognostic (1.02e-1)" IGHV2-70 ENSG00000274576 "Immunoglobulin heavy variable 2-70" P01814 14 106770577-106771020 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "lymphoid tissue: 678.8;stomach 1: 472.0" "Cell type enhanced" "Detected in single" "Plasma cells: 2.9" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebral cortex: 8.4" "Group enriched" "Detected in some" 242 "memory B-cell: 24.7;naive B-cell: 23.5" "Lineage enriched" "Detected in single" 248 "B-cells: 24.7" "Cancer enriched" "Detected in some" 5 "lymphoma: 124.6" "Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 44: Plasma cells - Antibody production & secretion" "unprognostic (2.50e-1)" "unprognostic (1.01e-3)" "unprognostic (3.02e-2)" "unprognostic (1.10e-1)" "unprognostic (1.58e-1)" "unprognostic (1.06e-2)" "unprognostic (1.96e-2)" "unprognostic (2.82e-1)" "unprognostic (1.01e-3)" "unprognostic (1.15e-1)" "unprognostic (4.57e-2)" "unprognostic (1.77e-2)" "unprognostic (2.88e-1)" "unprognostic (2.94e-2)" "unprognostic (1.53e-1)" "unprognostic (1.41e-1)" "unprognostic (3.06e-1)" "unprognostic (1.02e-2)" "unprognostic (5.35e-2)" "unprognostic (1.88e-1)" "unprognostic (2.86e-2)" "unprognostic (3.60e-1)" "unprognostic (5.63e-2)" "unprognostic (1.12e-1)" IGHV2-70D ENSG00000211974 "Immunoglobulin heavy variable 2-70D" A0A0C4DH43 14 106723574-106724093 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 34.4;lymphoid tissue: 85.3;stomach 1: 44.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 68 "memory B-cell: 9.7;naive B-cell: 3.8" "Lineage enriched" "Detected in single" 98 "B-cells: 9.7" "Cancer enriched" "Detected in single" 5 "lymphoma: 2.7" "Adrenal gland - Plasma cells, Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 44: Plasma cells - Antibody production & secretion" "unprognostic (2.35e-1)" "unprognostic (2.40e-3)" "unprognostic (1.29e-2)" "unprognostic (7.14e-2)" "unprognostic (1.08e-1)" "unprognostic (2.45e-1)" "unprognostic (2.23e-2)" "unprognostic (3.05e-1)" "unprognostic (2.18e-1)" "unprognostic (1.01e-2)" "unprognostic (1.05e-2)" "unprognostic (4.49e-1)" "unprognostic (4.00e-2)" "unprognostic (2.61e-2)" "unprognostic (4.11e-2)" "unprognostic (1.08e-1)" "unprognostic (9.45e-2)" "unprognostic (2.00e-2)" "unprognostic (1.11e-1)" "unprognostic (3.06e-3)" "unprognostic (3.34e-1)" "unprognostic (1.08e-1)" "unprognostic (1.55e-2)" "unprognostic (5.02e-1)" "unprognostic (1.05e-1)" "unprognostic (2.38e-1)" IGHV2OR16-5 IGHV2/OR16-5 ENSG00000259303 "Immunoglobulin heavy variable 2/OR16-5 (non-functional)" 16 32847713-32848156 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 6 "epididymis: 4.5;intestine: 1.7;lymphoid tissue: 3.0;salivary gland: 1.3;stomach 1: 4.9" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Skin Cutaneous Melanoma (TCGA): 2.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Minor Salivary Gland - Plasma cells" NA NA "Cluster 17: Intestine - Digestion" "Cluster 9: Skin cancer - Melanin biosynthesis" "unprognostic (6.61e-2)" "unprognostic (5.85e-2)" "unprognostic (2.25e-1)" IGHV3-11 ENSG00000211941 "Immunoglobulin heavy variable 3-11" P01762 14 106116635-106117204 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 205.9;lymphoid tissue: 572.8;stomach 1: 194.3" "Group enriched" "Detected in some" 9 "Gastric chief cells: 3.3;Plasma cells: 12.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 446 "memory B-cell: 43.2;naive B-cell: 45.9" "Lineage enriched" "Detected in single" 459 "B-cells: 45.9" "Cancer enriched" "Detected in some" 14 "lymphoma: 17.1" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 78: Plasma cells - Antibody production & ER-stress response" "unprognostic (1.68e-2)" "unprognostic (1.33e-3)" "unprognostic (2.16e-1)" "unprognostic (1.51e-1)" "unprognostic (3.63e-1)" "unprognostic (4.40e-3)" "unprognostic (2.84e-1)" "potential prognostic favorable (3.02e-5)" "unprognostic (1.81e-1)" "unprognostic (4.81e-2)" "unprognostic (4.97e-2)" "unprognostic (1.11e-2)" "unprognostic (2.00e-1)" "unprognostic (1.08e-1)" "unprognostic (2.68e-2)" "unprognostic (3.04e-2)" "unprognostic (4.09e-2)" "unprognostic (2.37e-2)" "unprognostic (4.63e-1)" "unprognostic (2.53e-1)" "unprognostic (4.12e-2)" "unprognostic (3.28e-1)" "unprognostic (8.62e-3)" "unprognostic (1.91e-1)" "unprognostic (2.30e-1)" "unprognostic (2.78e-2)" "unprognostic (3.55e-1)" "unprognostic (2.76e-1)" "unprognostic (4.65e-1)" IGHV3-13 ENSG00000211942 "Immunoglobulin heavy variable 3-13" P01766 14 106129540-106130072 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 63.0;lymphoid tissue: 128.3;urinary bladder: 85.0" "Cell type enriched" "Detected in single" 21 "Plasma cells: 2.7" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 48.3" "Not detected" "Not detected" "Group enriched" "Detected in some" 194 "memory B-cell: 18.9;naive B-cell: 19.7" "Lineage enriched" "Detected in single" 197 "B-cells: 19.7" "Not detected" "Not detected" "Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 67: Plasma cells - Plasma cell differentiation" "unprognostic (6.06e-3)" "potential prognostic favorable (5.42e-5)" "unprognostic (1.82e-2)" "unprognostic (6.70e-2)" "unprognostic (1.98e-1)" "unprognostic (1.59e-2)" "potential prognostic favorable (8.85e-7)" "unprognostic (6.92e-1)" "unprognostic (3.63e-2)" "unprognostic (1.77e-1)" "unprognostic (5.90e-2)" "unprognostic (1.87e-1)" "unprognostic (2.37e-2)" "unprognostic (5.41e-2)" "unprognostic (6.24e-2)" "unprognostic (4.33e-3)" "unprognostic (9.02e-2)" "unprognostic (2.48e-1)" "unprognostic (9.61e-3)" "unprognostic (5.82e-2)" "unprognostic (1.69e-1)" "unprognostic (1.93e-1)" "unprognostic (1.74e-2)" "unprognostic (2.24e-1)" "unprognostic (1.26e-2)" "unprognostic (3.27e-1)" "unprognostic (3.34e-1)" "unprognostic (4.21e-1)" IGHV3-15 ENSG00000211943 "Immunoglobulin heavy variable 3-15" A0A0B4J1V0 14 106153624-106154163 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 181.2;lymphoid tissue: 357.6;salivary gland: 174.5;stomach 1: 109.1;urinary bladder: 166.5" "Cell type enriched" "Detected in single" 1427 "Plasma cells: 470.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 9 "MAIT T-cell: 21.7;memory B-cell: 26.1" "Group enriched" "Detected in many" 9 "B-cells: 26.1;T-cells: 21.7" "Group enriched" "Detected in some" 65 "Leukemia: 13.6;lymphoma: 27.0" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 5: Spleen - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 78: Plasma cells - Antibody production & ER-stress response" "unprognostic (3.41e-3)" "unprognostic (5.69e-3)" "unprognostic (7.78e-2)" "unprognostic (1.13e-1)" "unprognostic (1.12e-1)" "unprognostic (9.22e-2)" "unprognostic (4.76e-3)" "unprognostic (3.30e-1)" "unprognostic (4.97e-2)" "unprognostic (2.48e-1)" "unprognostic (1.78e-1)" "unprognostic (3.11e-2)" "unprognostic (3.62e-2)" "unprognostic (1.20e-1)" "unprognostic (1.77e-1)" "unprognostic (6.27e-2)" "unprognostic (9.54e-3)" "unprognostic (1.12e-1)" "unprognostic (2.92e-1)" "unprognostic (4.02e-3)" "unprognostic (2.91e-1)" "unprognostic (4.15e-2)" "unprognostic (1.19e-3)" "unprognostic (3.67e-2)" "unprognostic (3.52e-1)" "unprognostic (9.75e-2)" "unprognostic (9.56e-3)" "unprognostic (1.73e-1)" IGHV3-16 ENSG00000211944 "Immunoglobulin heavy variable 3-16 (non-functional)" A0A0C4DH30 14 106165205-106165730 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 59: Leukemia - T-cell receptor" IGHV3-20 ENSG00000211946 "Immunoglobulin heavy variable 3-20" A0A0C4DH32 14 106210936-106211453 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 93.4;lymphoid tissue: 202.4;stomach 1: 115.1;urinary bladder: 76.9" "Cell type enriched" "Detected in single" 16 "Plasma cells: 1.7" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 243 "memory B-cell: 28.6;naive B-cell: 19.9" "Lineage enriched" "Detected in single" 287 "B-cells: 28.6" "Cancer enhanced" "Detected in single" "Leukemia: 1.5" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 35: RS4;11 - Unknown function" "Cluster 78: Plasma cells - Antibody production & ER-stress response" "unprognostic (4.23e-2)" "potential prognostic favorable (6.37e-6)" "unprognostic (4.77e-2)" "unprognostic (1.29e-1)" "unprognostic (4.85e-2)" "potential prognostic favorable (6.50e-4)" "unprognostic (4.32e-2)" "unprognostic (8.33e-2)" "unprognostic (9.13e-2)" "unprognostic (1.48e-1)" "unprognostic (1.70e-1)" "unprognostic (1.06e-2)" "unprognostic (1.49e-2)" "unprognostic (1.15e-2)" "unprognostic (8.44e-2)" "unprognostic (4.00e-2)" "unprognostic (1.77e-1)" "unprognostic (2.15e-1)" "unprognostic (4.64e-3)" "unprognostic (3.02e-1)" "unprognostic (2.69e-2)" "unprognostic (2.68e-1)" "unprognostic (1.82e-1)" "unprognostic (5.64e-2)" "unprognostic (1.68e-1)" "unprognostic (9.29e-2)" "unprognostic (5.49e-1)" IGHV3-21 ENSG00000211947 "Immunoglobulin heavy variable 3-21" A0A0B4J1V1 14 106235064-106235594 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 212.4;lymphoid tissue: 372.5;salivary gland: 204.5" "Cell type enriched" "Detected in some" 17 "Plasma cells: 18.8" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 197.7" "Region enhanced" "Detected in single" "white matter: 1.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 18 "lymphoma: 60.7" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 5: Spleen - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 78: Plasma cells - Antibody production & ER-stress response" "unprognostic (4.32e-2)" "unprognostic (1.06e-2)" "unprognostic (9.09e-2)" "unprognostic (2.37e-1)" "unprognostic (9.49e-2)" "unprognostic (5.29e-2)" "unprognostic (3.90e-2)" "unprognostic (8.97e-3)" "unprognostic (2.94e-2)" "unprognostic (3.48e-3)" "unprognostic (6.32e-2)" "unprognostic (4.49e-2)" "potential prognostic favorable (9.91e-4)" "unprognostic (5.74e-2)" "unprognostic (1.82e-1)" "unprognostic (1.03e-1)" "unprognostic (1.64e-1)" "unprognostic (1.59e-1)" "unprognostic (1.59e-1)" "unprognostic (1.86e-2)" "unprognostic (4.64e-1)" "unprognostic (1.71e-1)" "unprognostic (2.16e-1)" "unprognostic (3.05e-1)" "unprognostic (6.18e-1)" "unprognostic (3.11e-1)" "unprognostic (5.36e-2)" "unprognostic (1.84e-2)" IGHV3-23 ENSG00000211949 "Immunoglobulin heavy variable 3-23" P01764 14 106268606-106269140 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1574.2;lymphoid tissue: 2792.2;stomach 1: 995.6" "Cell type enriched" "Detected in some" 48 "Plasma cells: 105.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 404 "memory B-cell: 550.6;naive B-cell: 338.3" "Lineage enriched" "Detected in many" 501 "B-cells: 550.6" "Cancer enriched" "Detected in some" 18 "Myeloma: 724.1" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 78: Plasma cells - Antibody production & ER-stress response" 1 "unprognostic (4.82e-2)" "unprognostic (1.28e-3)" "unprognostic (9.79e-2)" "unprognostic (6.53e-2)" "unprognostic (4.99e-2)" "unprognostic (1.95e-2)" "unprognostic (1.51e-2)" "unprognostic (1.03e-3)" "unprognostic (1.53e-1)" "unprognostic (5.57e-3)" "unprognostic (6.65e-2)" "unprognostic (9.47e-3)" "unprognostic (3.35e-1)" "unprognostic (4.67e-2)" "unprognostic (5.47e-3)" "unprognostic (5.93e-2)" "unprognostic (5.67e-2)" "unprognostic (1.05e-2)" "unprognostic (2.08e-1)" "unprognostic (1.38e-1)" "unprognostic (1.71e-3)" "unprognostic (1.45e-1)" "unprognostic (1.21e-2)" "unprognostic (2.76e-1)" "unprognostic (2.11e-2)" "unprognostic (1.40e-1)" "unprognostic (1.68e-1)" "unprognostic (1.23e-1)" "unprognostic (1.38e-1)" IGHV3-30 ENSG00000270550 "Immunoglobulin heavy variable 3-30" "P01768, P0DP03" 14 106335082-106335613 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 499.5;lymphoid tissue: 1208.7;salivary gland: 438.6;stomach 1: 538.1;urinary bladder: 355.8" "Cell type enriched" "Detected in some" 5 "Plasma cells: 11.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 408 "memory B-cell: 164.7;naive B-cell: 137.2" "Lineage enriched" "Detected in single" 445 "B-cells: 164.7" "Cancer enriched" "Detected in some" 7 "Myeloma: 279.8" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 78: Plasma cells - Antibody production & ER-stress response" "unprognostic (1.68e-1)" "potential prognostic favorable (2.75e-4)" "unprognostic (2.05e-2)" "unprognostic (3.42e-1)" "unprognostic (1.96e-1)" "unprognostic (3.71e-3)" "potential prognostic favorable (1.09e-4)" "unprognostic (2.88e-2)" "potential prognostic unfavorable (7.69e-4)" "unprognostic (8.73e-2)" "potential prognostic unfavorable (5.58e-4)" "unprognostic (1.41e-1)" "unprognostic (6.65e-2)" "unprognostic (3.18e-2)" "unprognostic (7.36e-2)" "unprognostic (1.19e-1)" "unprognostic (1.27e-2)" "unprognostic (1.47e-1)" "unprognostic (2.72e-1)" "unprognostic (7.13e-3)" "unprognostic (1.56e-1)" "unprognostic (1.06e-1)" "unprognostic (7.70e-2)" "unprognostic (1.73e-1)" "unprognostic (2.06e-1)" "unprognostic (1.08e-1)" IGHV3-33 ENSG00000211955 "Immunoglobulin heavy variable 3-33" P01772 14 106359793-106360324 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 997.3;lymphoid tissue: 2217.4;stomach 1: 1673.0" "Cell type enriched" "Detected in some" 43 "Plasma cells: 64.0" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebral cortex: 6.6" "Group enriched" "Detected in many" 101 "memory B-cell: 380.3;naive B-cell: 365.8" "Lineage enriched" "Detected in many" 103 "B-cells: 380.3" "Cancer enriched" "Detected in some" 6 "lymphoma: 24.3" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 44: Plasma cells - Antibody production & secretion" "unprognostic (1.17e-1)" "unprognostic (1.30e-3)" "unprognostic (1.50e-2)" "unprognostic (9.71e-2)" "unprognostic (3.07e-1)" "potential prognostic unfavorable (3.31e-4)" "unprognostic (1.89e-1)" "potential prognostic favorable (3.60e-5)" "unprognostic (3.06e-1)" "unprognostic (4.14e-2)" "unprognostic (9.65e-2)" "unprognostic (1.05e-3)" "unprognostic (1.37e-1)" "unprognostic (5.31e-2)" "unprognostic (3.55e-2)" "unprognostic (8.30e-2)" "unprognostic (1.06e-1)" "unprognostic (4.67e-2)" "unprognostic (1.73e-1)" "unprognostic (6.30e-2)" "unprognostic (7.29e-3)" "unprognostic (2.73e-1)" "unprognostic (1.01e-2)" "unprognostic (1.90e-1)" "unprognostic (3.60e-1)" "unprognostic (5.40e-2)" "unprognostic (1.30e-1)" "unprognostic (2.15e-1)" "unprognostic (2.41e-1)" IGHV3-35 ENSG00000211957 "Immunoglobulin heavy variable 3-35 (non-functional)" A0A0C4DH35 14 106389392-106389858 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 13.2;lymphoid tissue: 12.1;salivary gland: 7.1;stomach 1: 15.7;urinary bladder: 19.2" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 9.6" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 16 "memory B-cell: 3.7" "Lineage enriched" "Detected in single" 35 "B-cells: 3.7" "Not detected" "Not detected" "Adipose visceral - Plasma cells, Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Prostate - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 51: Myeloma - Immunoglobulins" "potential prognostic favorable (5.52e-4)" "unprognostic (1.23e-1)" "unprognostic (4.09e-2)" "unprognostic (5.79e-2)" "unprognostic (1.59e-3)" "unprognostic (6.60e-2)" "unprognostic (9.05e-2)" "unprognostic (5.38e-2)" "unprognostic (8.70e-2)" "unprognostic (2.05e-1)" "unprognostic (2.41e-2)" "unprognostic (3.90e-1)" "unprognostic (4.54e-2)" "unprognostic (7.97e-2)" "unprognostic (1.46e-1)" "unprognostic (8.00e-2)" "unprognostic (5.67e-2)" "unprognostic (3.78e-2)" IGHV3-38 ENSG00000211958 "Immunoglobulin heavy variable 3-38 (non-functional)" A0A0C4DH36 14 106410493-106411021 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 9.4;lymphoid tissue: 9.7;stomach 1: 5.5;urinary bladder: 6.8" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 25 "memory B-cell: 3.4;naive B-cell: 1.5" "Lineage enriched" "Detected in single" 34 "B-cells: 3.4" "Cancer enriched" "Detected in single" 5 "prostate cancer: 1.4" "Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 60: Prostate cancer - Unknown function" "potential prognostic favorable (3.58e-7)" "unprognostic (7.81e-2)" "unprognostic (3.36e-2)" "unprognostic (2.43e-1)" "unprognostic (3.65e-3)" "unprognostic (1.46e-1)" "unprognostic (8.33e-2)" "unprognostic (2.96e-1)" "unprognostic (2.94e-2)" "unprognostic (1.46e-1)" "unprognostic (5.71e-2)" "unprognostic (7.72e-2)" "unprognostic (4.64e-2)" "unprognostic (2.33e-1)" "unprognostic (2.25e-1)" "unprognostic (2.36e-1)" "unprognostic (2.27e-1)" "unprognostic (7.82e-2)" "unprognostic (6.04e-1)" IGHV3-43 ENSG00000232216 "Immunoglobulin heavy variable 3-43" A0A0B4J1X8 14 106470264-106470800 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 198.3;stomach 1: 296.0;urinary bladder: 143.8" "Cell type enriched" "Detected in single" 75 "Plasma cells: 29.0" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "medulla oblongata: 1.5" "Group enriched" "Detected in some" 319 "memory B-cell: 29.5;naive B-cell: 39.2" "Lineage enriched" "Detected in single" 364 "B-cells: 39.2" "Not detected" "Not detected" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 78: Plasma cells - Antibody production & ER-stress response" "unprognostic (4.47e-3)" "potential prognostic favorable (1.97e-4)" "unprognostic (1.66e-2)" "unprognostic (1.59e-1)" "unprognostic (1.77e-1)" "unprognostic (4.67e-3)" "unprognostic (5.32e-1)" "unprognostic (3.17e-2)" "unprognostic (3.66e-1)" "unprognostic (7.81e-2)" "unprognostic (2.09e-2)" "unprognostic (8.62e-2)" "unprognostic (8.48e-3)" "unprognostic (1.34e-1)" "unprognostic (2.14e-1)" "unprognostic (4.84e-3)" "unprognostic (3.40e-1)" "unprognostic (1.04e-1)" "unprognostic (2.10e-2)" "unprognostic (7.30e-3)" "unprognostic (2.20e-2)" "unprognostic (2.50e-2)" "unprognostic (2.13e-1)" "unprognostic (2.94e-1)" "unprognostic (1.36e-1)" "unprognostic (1.11e-1)" "unprognostic (2.99e-1)" IGHV3-48 ENSG00000211964 "Immunoglobulin heavy variable 3-48" P01763 14 106537810-106538344 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 484.5;lymphoid tissue: 801.3;stomach 1: 380.8" "Cell type enriched" "Detected in some" 12 "Plasma cells: 15.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in some" 4 "cerebral cortex: 2.7;medulla oblongata: 1.5;pons: 1.5" "Group enriched" "Detected in some" 527 "memory B-cell: 187.8;naive B-cell: 97.9" "Lineage enriched" "Detected in single" 692 "B-cells: 187.8" "Group enriched" "Detected in some" 285 "lymphoma: 65.7;Myeloma: 21.6" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 44: Plasma cells - Antibody production & secretion" "unprognostic (1.63e-2)" "unprognostic (7.03e-3)" "unprognostic (1.40e-2)" "unprognostic (9.91e-2)" "unprognostic (3.00e-1)" "unprognostic (4.35e-2)" "unprognostic (7.19e-2)" "potential prognostic favorable (3.17e-4)" "unprognostic (1.12e-1)" "unprognostic (5.88e-3)" "unprognostic (6.12e-2)" "unprognostic (2.02e-2)" "unprognostic (1.86e-2)" "unprognostic (7.07e-3)" "unprognostic (6.40e-2)" "unprognostic (9.48e-2)" "unprognostic (1.12e-1)" "unprognostic (6.76e-2)" "unprognostic (3.40e-1)" "unprognostic (4.43e-1)" "unprognostic (1.32e-2)" "unprognostic (1.22e-1)" "unprognostic (1.64e-2)" "unprognostic (1.32e-1)" "unprognostic (2.33e-1)" "unprognostic (1.66e-1)" "unprognostic (1.20e-1)" "unprognostic (1.47e-1)" "unprognostic (3.43e-1)" IGHV3-49 ENSG00000211965 "Immunoglobulin heavy variable 3-49" A0A0A0MS15 14 106556936-106557477 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 197.1;lymphoid tissue: 348.9;stomach 1: 171.2" "Cell type enriched" "Detected in some" 8 "Plasma cells: 30.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 186 "memory B-cell: 59.6;naive B-cell: 42.4" "Lineage enriched" "Detected in single" 217 "B-cells: 59.6" "Not detected" "Not detected" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Testis - Late spermatids, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 13: Non-specific - Mixed function" "Cluster 78: Plasma cells - Antibody production & ER-stress response" "unprognostic (5.27e-2)" "potential prognostic favorable (3.42e-4)" "unprognostic (2.16e-2)" "unprognostic (3.14e-2)" "unprognostic (2.25e-2)" "unprognostic (3.47e-1)" "potential prognostic favorable (5.41e-5)" "unprognostic (5.18e-2)" "unprognostic (2.15e-1)" "potential prognostic unfavorable (1.06e-4)" "unprognostic (4.94e-2)" "unprognostic (7.91e-2)" "unprognostic (5.42e-3)" "unprognostic (2.68e-2)" "unprognostic (1.08e-1)" "unprognostic (9.29e-2)" "unprognostic (1.67e-1)" "unprognostic (2.98e-1)" "unprognostic (2.97e-3)" "unprognostic (1.70e-1)" "unprognostic (5.89e-2)" "unprognostic (2.37e-1)" "unprognostic (1.90e-2)" "unprognostic (1.06e-1)" "unprognostic (2.72e-1)" "unprognostic (1.23e-1)" "unprognostic (5.40e-1)" IGHV3-53 ENSG00000211967 "Immunoglobulin heavy variable 3-53" P01767 14 106592676-106593347 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 76.7;lymphoid tissue: 121.2;salivary gland: 30.4;stomach 1: 40.9" "Cell type enriched" "Detected in single" 16 "Plasma cells: 1.7" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 98 "memory B-cell: 54.9;naive B-cell: 52.9" "Lineage enriched" "Detected in single" 100 "B-cells: 54.9" "Group enriched" "Detected in some" 113 "Leukemia: 8.2;lymphoma: 19.1" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 44: Plasma cells - Antibody production & secretion" "unprognostic (2.03e-1)" "unprognostic (2.44e-3)" "unprognostic (2.14e-2)" "unprognostic (7.37e-2)" "unprognostic (4.44e-1)" "potential prognostic favorable (3.32e-4)" "unprognostic (1.32e-1)" "unprognostic (1.07e-1)" "unprognostic (1.71e-2)" "unprognostic (5.21e-3)" "unprognostic (8.00e-2)" "unprognostic (3.08e-2)" "unprognostic (3.39e-2)" "unprognostic (3.03e-2)" "unprognostic (6.37e-2)" "unprognostic (4.77e-2)" "unprognostic (3.23e-1)" "unprognostic (1.79e-1)" "unprognostic (3.11e-3)" "unprognostic (3.86e-2)" "unprognostic (2.19e-2)" "unprognostic (4.54e-2)" "unprognostic (3.60e-1)" "unprognostic (2.07e-1)" "unprognostic (4.40e-1)" "unprognostic (1.94e-1)" "unprognostic (2.07e-1)" IGHV3-64 ENSG00000223648 "Immunoglobulin heavy variable 3-64" A0A075B6Q5 14 106657725-106658258 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 18.4;lymphoid tissue: 30.3;salivary gland: 20.7" "Cell type enriched" "Detected in single" 24 "Plasma cells: 2.4" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 20 "memory B-cell: 11.1" "Lineage enriched" "Detected in single" 111 "B-cells: 11.1" "Not detected" "Not detected" "Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 5: Spleen - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 78: Plasma cells - Antibody production & ER-stress response" "unprognostic (2.12e-1)" "unprognostic (7.44e-2)" "unprognostic (3.06e-2)" "unprognostic (4.32e-2)" "unprognostic (7.57e-3)" "unprognostic (1.50e-2)" "unprognostic (2.36e-3)" "unprognostic (1.21e-1)" "unprognostic (9.22e-3)" "unprognostic (8.97e-2)" "unprognostic (4.03e-2)" "unprognostic (5.81e-2)" "unprognostic (6.06e-2)" "unprognostic (2.13e-3)" "unprognostic (3.14e-2)" "unprognostic (7.59e-2)" "unprognostic (2.66e-2)" "unprognostic (1.42e-1)" "unprognostic (2.35e-3)" "unprognostic (5.88e-2)" "unprognostic (1.01e-2)" "unprognostic (4.29e-3)" "unprognostic (1.36e-1)" "unprognostic (1.45e-1)" IGHV3-64D ENSG00000282639 "Immunoglobulin heavy variable 3-64D" A0A0J9YX35 14 106088122-106088573 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 135.5;lymphoid tissue: 253.1" "Group enriched" "Detected in some" 15 "Parietal cells: 1.8;Plasma cells: 2.0" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 301 "memory B-cell: 43.4;naive B-cell: 18.8" "Lineage enriched" "Detected in single" 420 "B-cells: 43.4" "Cancer enhanced" "Detected in single" "Leukemia: 1.5" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 44: Plasma cells - Antibody production & secretion" "unprognostic (3.56e-1)" "potential prognostic favorable (9.41e-4)" "unprognostic (1.12e-3)" "unprognostic (9.84e-2)" "unprognostic (2.66e-2)" "unprognostic (2.50e-3)" "unprognostic (9.62e-3)" "unprognostic (1.20e-1)" "unprognostic (1.12e-2)" "unprognostic (1.93e-1)" "unprognostic (3.75e-2)" "unprognostic (3.04e-1)" "unprognostic (1.46e-1)" "unprognostic (8.83e-2)" "unprognostic (8.06e-2)" "unprognostic (8.72e-2)" "unprognostic (3.59e-1)" "unprognostic (1.12e-2)" "unprognostic (2.77e-1)" "unprognostic (1.45e-1)" "unprognostic (5.98e-2)" "unprognostic (1.34e-1)" "unprognostic (3.98e-1)" "unprognostic (2.05e-1)" IGHV3-66 ENSG00000211972 "Immunoglobulin heavy variable 3-66" A0A0C4DH42 14 106675017-106675544 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 44.4;intestine: 53.6;urinary bladder: 97.5" "Cell type enriched" "Detected in single" 14 "Plasma cells: 12.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 135 "memory B-cell: 39.3" "Lineage enriched" "Detected in single" 135 "B-cells: 39.3" "Group enriched" "Detected in some" 17 "Leukemia: 20.0;lymphoma: 26.7;Myeloma: 7.2" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 78: Plasma cells - Antibody production & ER-stress response" "unprognostic (2.47e-2)" "unprognostic (9.99e-3)" "unprognostic (1.98e-2)" "unprognostic (1.35e-1)" "unprognostic (3.45e-3)" "unprognostic (3.00e-3)" "unprognostic (5.45e-1)" "unprognostic (2.52e-2)" "unprognostic (6.44e-2)" "unprognostic (8.64e-3)" "unprognostic (6.25e-2)" "unprognostic (1.26e-2)" "unprognostic (3.25e-2)" "unprognostic (1.45e-1)" "potential prognostic unfavorable (7.84e-4)" "unprognostic (7.48e-3)" "unprognostic (4.40e-1)" "unprognostic (6.95e-3)" "unprognostic (6.36e-3)" "unprognostic (9.99e-2)" "unprognostic (2.02e-1)" "unprognostic (1.07e-1)" "unprognostic (2.86e-1)" "unprognostic (4.02e-2)" "unprognostic (3.68e-2)" "unprognostic (3.12e-1)" "unprognostic (1.26e-1)" IGHV3-7 ENSG00000211938 "Immunoglobulin heavy variable 3-7" P01780 14 106062151-106062683 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 433.4;lymphoid tissue: 899.2" "Cell type enriched" "Detected in some" 18 "Plasma cells: 102.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 148 "memory B-cell: 136.5;naive B-cell: 108.1" "Lineage enriched" "Detected in single" 165 "B-cells: 136.5" "Group enriched" "Detected in some" 327 "Leukemia: 220.1;lymphoma: 166.2;Myeloma: 182.7" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 39: Astrocytes - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 78: Plasma cells - Antibody production & ER-stress response" "unprognostic (4.27e-2)" "unprognostic (2.11e-3)" "unprognostic (1.99e-1)" "unprognostic (1.57e-2)" "unprognostic (3.52e-2)" "unprognostic (4.83e-2)" "unprognostic (9.05e-2)" "unprognostic (1.08e-3)" "unprognostic (1.91e-1)" "unprognostic (3.03e-1)" "unprognostic (1.17e-1)" "unprognostic (4.20e-2)" "unprognostic (9.49e-3)" "unprognostic (2.79e-1)" "unprognostic (1.68e-1)" "unprognostic (1.37e-1)" "unprognostic (6.31e-3)" "unprognostic (1.59e-1)" "unprognostic (2.87e-1)" "unprognostic (8.03e-2)" "unprognostic (2.08e-3)" "unprognostic (4.67e-2)" "unprognostic (1.81e-1)" "unprognostic (1.01e-2)" "unprognostic (1.39e-1)" "unprognostic (8.37e-2)" "unprognostic (7.72e-2)" "unprognostic (2.27e-1)" "unprognostic (1.86e-1)" IGHV3-72 ENSG00000225698 "Immunoglobulin heavy variable 3-72" A0A0B4J1Y9 14 106790694-106791233 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 76.5;lymphoid tissue: 114.1;urinary bladder: 89.3" "Cell type enriched" "Detected in single" 76 "Plasma cells: 7.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 7 "memory B-cell: 48.4" "Lineage enriched" "Detected in single" 249 "B-cells: 48.4" "Cancer enriched" "Detected in single" 4 "lymphoma: 2.6" "Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 5: Spleen - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 44: Plasma cells - Antibody production & secretion" "unprognostic (1.25e-1)" "unprognostic (1.32e-2)" "unprognostic (7.12e-2)" "unprognostic (1.17e-2)" "unprognostic (2.17e-1)" "potential prognostic favorable (3.80e-4)" "unprognostic (2.37e-1)" "unprognostic (1.02e-1)" "potential prognostic unfavorable (6.53e-4)" "unprognostic (2.28e-2)" "unprognostic (1.36e-1)" "unprognostic (1.65e-1)" "unprognostic (5.05e-2)" "unprognostic (4.60e-2)" "unprognostic (9.59e-2)" "unprognostic (1.63e-2)" "unprognostic (2.35e-1)" "unprognostic (2.94e-3)" "unprognostic (5.03e-2)" "unprognostic (1.04e-2)" "unprognostic (1.07e-1)" "unprognostic (1.01e-1)" "unprognostic (3.57e-2)" "unprognostic (6.25e-2)" "unprognostic (1.26e-1)" "unprognostic (1.28e-1)" IGHV3-73 ENSG00000211976 "Immunoglobulin heavy variable 3-73" A0A0B4J1V6 14 106802694-106803233 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 132.5;lymphoid tissue: 76.8;urinary bladder: 76.6" "Cell type enriched" "Detected in single" 1075 "Plasma cells: 107.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 130.2" "Not detected" "Not detected" "Group enriched" "Detected in some" 87 "memory B-cell: 70.1;naive B-cell: 43.3" "Lineage enriched" "Detected in single" 107 "B-cells: 70.1" "Group enriched" "Detected in some" 232 "lymphoma: 13.6;Myeloma: 32.8" "Adipose visceral - Plasma cells, Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 77: Intestine - Digestion" "Cluster 55: Lymphoma - Immune response" "Cluster 78: Plasma cells - Antibody production & ER-stress response" "unprognostic (1.84e-1)" "unprognostic (3.79e-2)" "unprognostic (7.29e-2)" "unprognostic (3.72e-2)" "unprognostic (3.61e-2)" "potential prognostic favorable (8.72e-4)" "unprognostic (5.16e-2)" "unprognostic (1.70e-1)" "unprognostic (8.71e-2)" "unprognostic (1.51e-1)" "unprognostic (1.95e-3)" "unprognostic (1.63e-1)" "unprognostic (1.94e-1)" "unprognostic (8.52e-3)" "unprognostic (2.03e-1)" "unprognostic (3.01e-1)" "unprognostic (6.82e-2)" "unprognostic (6.90e-3)" "unprognostic (3.38e-1)" "unprognostic (9.71e-3)" "unprognostic (8.43e-2)" "unprognostic (2.11e-1)" "unprognostic (3.23e-2)" "unprognostic (9.00e-2)" "unprognostic (9.28e-2)" "unprognostic (1.55e-1)" IGHV3-74 ENSG00000224650 "Immunoglobulin heavy variable 3-74" A0A0B4J1X5 14 106810442-106811131 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 81.9;intestine: 102.7;lymphoid tissue: 291.0;salivary gland: 100.2" "Cell type enriched" "Detected in some" 17 "Plasma cells: 19.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "naive CD8 T-cell: 1.2" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in some" 5 "lymphoma: 39.4" "Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 5: Spleen - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 44: Plasma cells - Antibody production & secretion" "unprognostic (5.53e-2)" "unprognostic (2.19e-1)" "unprognostic (2.43e-1)" "unprognostic (3.20e-1)" "unprognostic (1.94e-1)" "unprognostic (4.16e-1)" "unprognostic (1.47e-1)" "unprognostic (1.62e-1)" "unprognostic (3.20e-2)" "unprognostic (2.60e-1)" "unprognostic (1.33e-1)" "unprognostic (2.84e-1)" "unprognostic (1.55e-1)" "unprognostic (7.20e-3)" "unprognostic (3.87e-2)" "unprognostic (4.02e-1)" "unprognostic (3.47e-1)" "unprognostic (2.45e-1)" "unprognostic (1.82e-1)" "unprognostic (1.23e-2)" "unprognostic (1.01e-1)" "unprognostic (2.25e-1)" "unprognostic (4.57e-1)" "unprognostic (3.22e-1)" "unprognostic (2.22e-1)" "unprognostic (2.25e-1)" "unprognostic (1.21e-2)" "unprognostic (1.86e-2)" IGHV3OR15-7 IGHV3/OR15-7 ENSG00000259490 "Immunoglobulin heavy variable 3/OR15-7 (pseudogene)" 15 19987656-19988117 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "intestine: 1.9;stomach 1: 1.7" "Cell type enriched" "Detected in single" 12 "Plasma cells: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" NA NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 78: Plasma cells - Antibody production & ER-stress response" IGHV3OR16-10 IGHV3/OR16-10 ENSG00000233732 "Immunoglobulin heavy variable 3/OR16-10 (non-functional)" 16 32995048-32995505 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "intestine: 7.4;lymphoid tissue: 9.6;salivary gland: 8.4;stomach 1: 8.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.7" "Lineage enriched" "Detected in single" 18 "B-cells: 1.7" "Cancer enriched" "Detected in single" 19 "lymphoma: 1.9" "Breast - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 51: Myeloma - Immunoglobulins" "unprognostic (3.46e-1)" "unprognostic (5.09e-1)" "unprognostic (3.38e-1)" "unprognostic (3.50e-2)" "unprognostic (1.86e-1)" "unprognostic (1.96e-1)" "unprognostic (1.25e-1)" "unprognostic (3.37e-1)" "unprognostic (2.34e-2)" IGHV3OR16-12 IGHV3/OR16-12 ENSG00000270467 "Immunoglobulin heavy variable 3/OR16-12 (non-functional)" 16 33802764-33803217 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 4 "intestine: 12.9;lymphoid tissue: 18.9;stomach 1: 9.2" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Stomach Adenocarcinoma (TCGA): 8.6" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 10 "memory B-cell: 4.6" "Lineage enriched" "Detected in single" 46 "B-cells: 4.6" "Not detected" "Not detected" "Breast - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 5: Rhabdoid - Unknown function" "unprognostic (1.08e-1)" "unprognostic (1.73e-2)" "unprognostic (3.63e-1)" "unprognostic (4.12e-2)" "unprognostic (4.48e-1)" "unprognostic (8.68e-3)" "unprognostic (5.67e-3)" "unprognostic (5.27e-2)" "unprognostic (2.95e-3)" "unprognostic (1.30e-1)" "unprognostic (1.18e-2)" "unprognostic (2.05e-1)" "unprognostic (3.37e-1)" "unprognostic (1.90e-1)" "unprognostic (5.62e-1)" "unprognostic (2.99e-1)" IGHV3OR16-13 IGHV3/OR16-13 ENSG00000271178 "Immunoglobulin heavy variable 3/OR16-13 (non-functional)" 16 33827214-33827661 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "intestine: 6.6;lymphoid tissue: 27.8;salivary gland: 7.0" "Cell type enhanced" "Detected in single" "Gastric chief cells: 1.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 27 "memory B-cell: 18.2" "Lineage enriched" "Detected in single" 182 "B-cells: 18.2" "Cancer enriched" "Detected in single" 70 "lymphoma: 6.9" "Adipose visceral - Plasma cells, Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Prostate - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 5: Spleen - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 44: Plasma cells - Antibody production & secretion" "unprognostic (1.88e-2)" "unprognostic (1.59e-1)" "unprognostic (2.06e-2)" "unprognostic (2.79e-1)" "unprognostic (7.01e-3)" "unprognostic (7.75e-2)" "unprognostic (3.10e-2)" "unprognostic (4.31e-2)" "unprognostic (1.22e-1)" "unprognostic (4.02e-1)" "unprognostic (3.75e-1)" "unprognostic (1.13e-1)" "unprognostic (2.59e-1)" "unprognostic (1.69e-1)" "unprognostic (3.29e-1)" "unprognostic (3.46e-1)" IGHV3OR16-17 IGHV3/OR16-17 ENSG00000259680 "Immunoglobulin heavy variable 3/OR16-17 (non-functional)" 16 33844784-33845229 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "intestine: 10.7;lymphoid tissue: 22.7;stomach 1: 11.0" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 21 "memory B-cell: 1.6;naive B-cell: 2.6" "Lineage enriched" "Detected in single" 26 "B-cells: 2.6" "Cancer enriched" "Detected in single" 42 "Myeloma: 8.4" "Breast - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" NA NA "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 44: Plasma cells - Antibody production & secretion" "unprognostic (2.16e-3)" "unprognostic (2.72e-1)" "unprognostic (3.21e-1)" "unprognostic (1.59e-1)" "potential prognostic favorable (3.85e-4)" "unprognostic (2.87e-2)" "unprognostic (1.73e-1)" "unprognostic (1.42e-1)" "unprognostic (1.65e-1)" "unprognostic (2.47e-2)" "unprognostic (2.48e-1)" "unprognostic (1.67e-1)" "unprognostic (1.90e-1)" "unprognostic (1.52e-1)" "unprognostic (6.26e-1)" "unprognostic (6.01e-2)" IGHV3OR16-8 IGHV3/OR16-8 ENSG00000271130 "Immunoglobulin heavy variable 3/OR16-8 (non-functional)" 16 33009175-33009620 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 30.0;lymphoid tissue: 46.5;stomach 1: 32.0;urinary bladder: 38.9" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 14 "memory B-cell: 7.5" "Lineage enriched" "Detected in single" 75 "B-cells: 7.5" "Cancer enriched" "Detected in single" 13 "Myeloma: 3.1" "Adipose visceral - Plasma cells, Breast - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 44: Plasma cells - Antibody production & secretion" "unprognostic (3.02e-1)" "potential prognostic favorable (4.04e-4)" "unprognostic (5.47e-2)" "unprognostic (4.87e-2)" "unprognostic (4.43e-1)" "unprognostic (2.84e-3)" "unprognostic (3.68e-2)" "unprognostic (5.14e-3)" "unprognostic (6.51e-3)" "unprognostic (3.24e-2)" "unprognostic (6.49e-2)" "unprognostic (1.25e-3)" "unprognostic (2.50e-1)" "unprognostic (3.34e-2)" "unprognostic (1.38e-1)" "unprognostic (1.85e-1)" "unprognostic (5.13e-2)" "unprognostic (4.57e-1)" IGHV3OR16-9 IGHV3/OR16-9 ENSG00000270472 "Immunoglobulin heavy variable 3/OR16-9 (non-functional)" 16 32066065-32066358 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 67.4;lymphoid tissue: 81.5;salivary gland: 45.6;stomach 1: 70.9;urinary bladder: 47.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 133 "memory B-cell: 19.5;naive B-cell: 6.9" "Lineage enriched" "Detected in single" 195 "B-cells: 19.5" "Cancer enriched" "Detected in some" 11 "lymphoma: 15.0" "Adipose visceral - Plasma cells, Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 55: Lymphoma - Immune response" "unprognostic (5.04e-1)" "unprognostic (5.03e-3)" "unprognostic (2.54e-1)" "unprognostic (3.96e-2)" "unprognostic (1.51e-1)" "potential prognostic favorable (1.46e-4)" "potential prognostic unfavorable (3.73e-4)" "unprognostic (1.30e-1)" "unprognostic (1.14e-3)" "unprognostic (3.78e-1)" "unprognostic (9.09e-2)" "unprognostic (1.80e-1)" "unprognostic (1.14e-1)" "unprognostic (1.25e-1)" "unprognostic (1.56e-2)" "unprognostic (4.67e-1)" "unprognostic (4.82e-1)" "unprognostic (4.93e-2)" "unprognostic (2.09e-1)" "unprognostic (1.56e-1)" "unprognostic (1.97e-1)" "unprognostic (3.36e-1)" "unprognostic (2.76e-1)" "unprognostic (3.81e-1)" IGHV4-28 ENSG00000211952 "Immunoglobulin heavy variable 4-28" A0A0C4DH34 14 106324254-106324760 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 42.3;lymphoid tissue: 81.7;salivary gland: 37.4;stomach 1: 28.9;urinary bladder: 115.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 6 "spinal cord: 2.5" "Group enriched" "Detected in some" 207 "memory B-cell: 28.8;naive B-cell: 12.5" "Lineage enriched" "Detected in single" 289 "B-cells: 28.8" "Cancer enriched" "Detected in single" 10 "Myeloma: 3.4" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 7: Non-specific - Ribosome" "Cluster 55: Lymphoma - Immune response" "Cluster 67: Plasma cells - Plasma cell differentiation" "unprognostic (1.83e-1)" "potential prognostic favorable (4.92e-4)" "unprognostic (1.60e-2)" "unprognostic (4.50e-1)" "unprognostic (3.50e-2)" "potential prognostic favorable (1.54e-4)" "unprognostic (2.22e-1)" "unprognostic (4.06e-2)" "unprognostic (1.78e-2)" "unprognostic (4.40e-3)" "unprognostic (3.37e-2)" "unprognostic (6.73e-2)" "potential prognostic favorable (1.99e-5)" "unprognostic (1.52e-2)" "unprognostic (3.26e-1)" "unprognostic (1.27e-1)" "unprognostic (3.05e-1)" "unprognostic (2.70e-2)" "unprognostic (3.25e-3)" "unprognostic (2.42e-1)" "unprognostic (4.40e-2)" "unprognostic (4.52e-2)" "unprognostic (2.44e-1)" "unprognostic (5.57e-2)" "unprognostic (1.22e-1)" "unprognostic (3.14e-1)" "unprognostic (1.11e-1)" IGHV4-31 ENSG00000231475 "Immunoglobulin heavy variable 4-31" A0A087WSY4 14 106349283-106349792 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 436.1;urinary bladder: 179.2" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Lung Squamous Cell Carcinoma (TCGA): 128.0" "Region enhanced" "Detected in some" "spinal cord: 2.8" "Group enriched" "Detected in some" 48 "memory B-cell: 43.7;naive B-cell: 19.4" "Lineage enriched" "Detected in single" 66 "B-cells: 43.7" "Cancer enriched" "Detected in some" 12 "Myeloma: 35.4" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 7: Non-specific - Ribosome" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 44: Plasma cells - Antibody production & secretion" "unprognostic (5.21e-2)" "potential prognostic favorable (1.58e-4)" "unprognostic (3.32e-2)" "unprognostic (1.21e-1)" "unprognostic (1.50e-1)" "potential prognostic favorable (1.02e-4)" "potential prognostic unfavorable (1.50e-4)" "unprognostic (1.92e-1)" "unprognostic (1.36e-3)" "unprognostic (8.69e-2)" "unprognostic (8.57e-2)" "unprognostic (2.86e-1)" "unprognostic (3.35e-1)" "unprognostic (1.09e-2)" "unprognostic (1.67e-1)" "unprognostic (3.32e-1)" "unprognostic (8.65e-2)" "unprognostic (9.58e-3)" "unprognostic (6.54e-2)" "unprognostic (9.61e-2)" "unprognostic (1.73e-1)" "unprognostic (5.88e-1)" "unprognostic (2.34e-1)" "unprognostic (2.11e-1)" "unprognostic (1.80e-1)" "unprognostic (2.26e-1)" IGHV4-34 ENSG00000211956 "Immunoglobulin heavy variable 4-34" P06331 14 106373663-106374145 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 264.8;urinary bladder: 253.2" "Group enriched" "Detected in some" 5 "Gastric chief cells: 7.6;Mucous neck cells: 2.4;Plasma cells: 8.1;Platelets: 2.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "white matter: 2.5" "Immune cell enhanced" "Detected in single" "neutrophil: 1.1" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in some" 100 "lymphoma: 476.9" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 22: Non-specific - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 67: Plasma cells - Plasma cell differentiation" "unprognostic (2.70e-2)" "unprognostic (2.91e-2)" "unprognostic (2.65e-1)" "unprognostic (3.24e-1)" "unprognostic (2.83e-1)" "unprognostic (7.43e-2)" "unprognostic (2.41e-2)" "unprognostic (4.84e-2)" "potential prognostic favorable (1.85e-5)" "unprognostic (1.90e-1)" "unprognostic (1.10e-1)" "unprognostic (7.02e-2)" "unprognostic (4.67e-3)" "unprognostic (3.69e-2)" "unprognostic (1.33e-1)" "unprognostic (4.14e-1)" "unprognostic (4.06e-2)" "unprognostic (2.60e-1)" "unprognostic (6.98e-2)" "unprognostic (2.46e-2)" "unprognostic (1.79e-2)" "unprognostic (1.51e-2)" "unprognostic (5.03e-1)" "unprognostic (3.09e-1)" "unprognostic (8.08e-2)" "unprognostic (1.84e-1)" "unprognostic (2.03e-2)" "unprognostic (3.72e-2)" IGHV4-39 ENSG00000211959 "Immunoglobulin heavy variable 4-39" P01824 14 106421711-106422218 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 257.3;lymphoid tissue: 453.6;salivary gland: 243.9;urinary bladder: 506.1" "Group enriched" "Detected in some" 4 "Gastric chief cells: 8.7;Plasma cells: 26.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.6;naive B-cell: 1.7" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 40 "lymphoma: 89.4;Myeloma: 52.8" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 5: Spleen - Immune response" "Cluster 8: Immune cells - Immune response" "Cluster 13: Non-specific - Mixed function" "Cluster 78: Plasma cells - Antibody production & ER-stress response" "unprognostic (1.62e-1)" "unprognostic (3.37e-1)" "unprognostic (9.13e-2)" "unprognostic (9.30e-2)" "unprognostic (2.46e-1)" "unprognostic (2.56e-2)" "unprognostic (6.42e-2)" "unprognostic (1.23e-1)" "unprognostic (3.43e-2)" "unprognostic (6.89e-2)" "unprognostic (7.71e-2)" "unprognostic (3.08e-1)" "unprognostic (4.46e-2)" "unprognostic (5.35e-2)" "unprognostic (1.98e-1)" "unprognostic (2.34e-2)" "unprognostic (1.52e-1)" "unprognostic (1.19e-1)" "unprognostic (1.65e-2)" "unprognostic (1.37e-2)" "unprognostic (2.76e-2)" "unprognostic (3.76e-2)" "unprognostic (2.19e-2)" "unprognostic (2.10e-1)" "unprognostic (2.90e-1)" "unprognostic (4.24e-2)" "unprognostic (6.55e-2)" "unprognostic (6.21e-2)" IGHV4-4 ENSG00000276775 "Immunoglobulin heavy variable 4-4" A0A075B6R2 14 106011922-106012420 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 529.6;urinary bladder: 722.3" "Cell type enriched" "Detected in some" 18 "Plasma cells: 32.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in single" 10 "midbrain: 9.4" "Group enriched" "Detected in some" 23 "memory B-cell: 56.8;naive B-cell: 31.4" "Lineage enriched" "Detected in many" 29 "B-cells: 56.8" "Group enriched" "Detected in some" 49 "lymphoma: 23.3;Myeloma: 69.5" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 46: Brainstem - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 78: Plasma cells - Antibody production & ER-stress response" "unprognostic (4.75e-2)" "unprognostic (1.27e-2)" "unprognostic (8.05e-2)" "unprognostic (5.36e-2)" "unprognostic (8.48e-2)" "unprognostic (4.61e-2)" "potential prognostic favorable (1.11e-5)" "unprognostic (3.30e-1)" "unprognostic (4.11e-3)" "unprognostic (2.13e-1)" "unprognostic (1.26e-2)" "unprognostic (3.20e-2)" "unprognostic (1.91e-1)" "unprognostic (6.43e-2)" "unprognostic (1.75e-1)" "unprognostic (9.74e-3)" "unprognostic (1.19e-1)" "unprognostic (1.56e-1)" "unprognostic (1.49e-1)" "unprognostic (6.80e-2)" "unprognostic (3.16e-1)" "unprognostic (6.42e-2)" "unprognostic (2.50e-1)" "unprognostic (1.38e-1)" "unprognostic (1.48e-1)" "unprognostic (4.96e-1)" IGHV4-59 ENSG00000224373 "Immunoglobulin heavy variable 4-59" P01825 14 106627249-106627825 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 492.0;lymphoid tissue: 851.1;urinary bladder: 659.9" "Cell type enhanced" "Detected in some" "Foveolar cells: 6.8;Gastric chief cells: 16.4;Mucous neck cells: 4.3;Parietal cells: 7.1;Plasma cells: 24.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "spinal cord: 3.7" "Group enriched" "Detected in some" 37 "memory B-cell: 169.4;naive B-cell: 77.5" "Lineage enriched" "Detected in many" 51 "B-cells: 169.4" "Cancer enriched" "Detected in some" 9 "lymphoma: 98.0" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 67: Plasma cells - Plasma cell differentiation" "unprognostic (4.31e-2)" "potential prognostic favorable (7.85e-5)" "unprognostic (6.57e-2)" "unprognostic (9.84e-2)" "unprognostic (1.90e-1)" "potential prognostic unfavorable (7.22e-4)" "potential prognostic favorable (3.28e-5)" "unprognostic (1.58e-1)" "unprognostic (1.31e-2)" "unprognostic (1.63e-1)" "unprognostic (1.50e-3)" "unprognostic (8.03e-2)" "unprognostic (1.94e-2)" "unprognostic (5.11e-2)" "unprognostic (8.84e-2)" "unprognostic (2.48e-1)" "unprognostic (2.63e-2)" "unprognostic (3.87e-1)" "unprognostic (2.85e-1)" "unprognostic (5.57e-2)" "unprognostic (1.89e-1)" "unprognostic (2.13e-2)" "unprognostic (2.30e-1)" "unprognostic (8.86e-2)" "unprognostic (5.88e-2)" "unprognostic (1.09e-1)" "unprognostic (2.63e-1)" "unprognostic (3.09e-1)" IGHV4-61 ENSG00000211970 "Immunoglobulin heavy variable 4-61" A0A0C4DH41 14 106639119-106639657 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 193.1;lymphoid tissue: 360.0;stomach 1: 134.4" "Group enriched" "Detected in some" 19 "Foveolar cells: 1.2;Gastric chief cells: 1.1;Mucous neck cells: 1.6;Plasma cells: 4.0" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 43 "memory B-cell: 39.1;naive B-cell: 25.6" "Lineage enriched" "Detected in single" 52 "B-cells: 39.1" "Cancer enriched" "Detected in single" 47 "lymphoma: 20.7" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 67: Plasma cells - Plasma cell differentiation" "unprognostic (3.27e-1)" "potential prognostic favorable (4.41e-4)" "unprognostic (7.27e-3)" "unprognostic (1.38e-1)" "unprognostic (1.80e-1)" "potential prognostic favorable (1.11e-4)" "unprognostic (2.27e-2)" "unprognostic (1.12e-1)" "potential prognostic unfavorable (5.09e-4)" "unprognostic (1.81e-1)" "unprognostic (6.99e-2)" "unprognostic (7.65e-3)" "unprognostic (3.34e-1)" "unprognostic (1.34e-1)" "unprognostic (1.69e-2)" "unprognostic (1.35e-1)" "unprognostic (1.42e-1)" "unprognostic (2.46e-3)" "unprognostic (8.75e-2)" "unprognostic (9.87e-2)" "unprognostic (8.83e-3)" "unprognostic (2.97e-1)" "unprognostic (1.85e-1)" "unprognostic (3.82e-1)" "unprognostic (3.57e-1)" "unprognostic (2.18e-1)" IGHV4OR15-8 "IGHV4/OR15-8, IGHV4OR158, VSIG6" ENSG00000259261 "Immunoglobulin heavy variable 4/OR15-8 (non-functional)" 15 22184967-22185402 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "intestine: 1.8;lymphoid tissue: 1.3;urinary bladder: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Plasma cells, Minor Salivary Gland - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells" NA NA "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "unprognostic (4.01e-1)" "unprognostic (1.35e-2)" IGHV5-10-1 IGHV5-A ENSG00000282651 "Immunoglobulin heavy variable 5-10-1" A0A0J9YXX1 14 106107972-106108464 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 296.2;lymphoid tissue: 528.5" "Cell type enriched" "Detected in single" 14 "Plasma cells: 4.7" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Lung Squamous Cell Carcinoma (TCGA): 180.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 15 "memory B-cell: 75.0;naive B-cell: 67.0" "Lineage enriched" "Detected in many" 16 "B-cells: 75.0" "Group enriched" "Detected in some" 9 "Leukemia: 1.6;lymphoma: 3.4" "Adrenal gland - Plasma cells, Colon - Plasma cells, Liver - Plasma cells, Minor Salivary Gland - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" HPA006014 Approved "Immunoglobulin genes" Immunity NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 44: Plasma cells - Antibody production & secretion" "HPA006014: " "unprognostic (8.59e-2)" "unprognostic (9.67e-2)" "unprognostic (3.34e-1)" "unprognostic (9.73e-2)" "unprognostic (4.95e-2)" "unprognostic (2.61e-1)" "unprognostic (7.38e-2)" "unprognostic (3.75e-1)" "unprognostic (3.33e-2)" "unprognostic (3.39e-3)" "unprognostic (3.86e-2)" "unprognostic (4.06e-1)" "unprognostic (8.34e-2)" "unprognostic (3.37e-1)" "unprognostic (2.20e-2)" "unprognostic (5.38e-2)" "unprognostic (2.07e-1)" "unprognostic (1.74e-1)" "unprognostic (3.66e-1)" "unprognostic (8.80e-3)" "unprognostic (2.18e-1)" "unprognostic (9.17e-2)" "unprognostic (7.99e-3)" "unprognostic (2.30e-1)" "unprognostic (2.57e-1)" "unprognostic (3.17e-1)" IGHV5-51 ENSG00000211966 "Immunoglobulin heavy variable 5-51" A0A0C4DH38 14 106578744-106579236 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 252.4;lymphoid tissue: 511.7;salivary gland: 215.5;urinary bladder: 326.3" "Cell type enriched" "Detected in some" 9 "Plasma cells: 51.6" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 147.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 567 "lymphoma: 67.9" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" HPA006014 Approved "Immunoglobulin genes" Immunity NA NA "Cluster 5: Spleen - Immune response" "Cluster 8: Immune cells - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 78: Plasma cells - Antibody production & ER-stress response" "HPA006014: " "unprognostic (3.44e-3)" "unprognostic (6.05e-3)" "unprognostic (1.63e-1)" "unprognostic (7.19e-2)" "unprognostic (3.08e-1)" "unprognostic (1.97e-1)" "unprognostic (9.77e-2)" "unprognostic (2.27e-1)" "unprognostic (1.65e-1)" "unprognostic (1.44e-1)" "unprognostic (1.05e-2)" "unprognostic (4.27e-2)" "unprognostic (1.02e-2)" "unprognostic (5.33e-2)" "unprognostic (3.99e-3)" "unprognostic (5.49e-1)" "unprognostic (3.15e-1)" "unprognostic (2.42e-1)" "unprognostic (1.05e-1)" "potential prognostic favorable (1.81e-5)" "unprognostic (8.44e-2)" "unprognostic (1.19e-1)" "unprognostic (5.12e-2)" "unprognostic (1.85e-1)" "unprognostic (3.41e-3)" "unprognostic (2.99e-2)" "unprognostic (1.32e-1)" "unprognostic (3.56e-1)" IGHV6-1 ENSG00000211933 "Immunoglobulin heavy variable 6-1" A0A0B4J1U7 14 105939756-105940253 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 414.8;lymphoid tissue: 146.9" "Cell type enriched" "Detected in some" 7 "Plasma cells: 8.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 6 "naive B-cell: 20.0" "Lineage enriched" "Detected in single" 53 "B-cells: 20.0" "Not detected" "Not detected" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 17: Intestine - Digestion" "Cluster 44: Plasma cells - Antibody production & secretion" "unprognostic (2.78e-1)" "unprognostic (1.99e-1)" "unprognostic (1.88e-1)" "unprognostic (2.30e-2)" "unprognostic (2.44e-1)" "unprognostic (1.80e-1)" "unprognostic (1.52e-1)" "unprognostic (1.91e-2)" "unprognostic (1.00e-2)" "unprognostic (1.48e-1)" "unprognostic (2.39e-1)" "unprognostic (3.92e-1)" "unprognostic (5.43e-1)" "unprognostic (3.83e-1)" "unprognostic (1.05e-1)" "unprognostic (1.50e-1)" "unprognostic (2.85e-2)" "unprognostic (7.08e-2)" "unprognostic (2.88e-2)" "unprognostic (4.34e-3)" "unprognostic (8.54e-2)" "unprognostic (7.83e-2)" "unprognostic (3.00e-1)" "unprognostic (9.13e-2)" "unprognostic (1.62e-1)" IGHV7-4-1 ENSG00000282122 "Immunoglobulin heavy variable 7-4-1" A0A0J9YVY3 14 106025145-106025630 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 91.3;lymphoid tissue: 124.4" "Cell type enriched" "Detected in single" 7 "Plasma cells: 1.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 83.5" "Region enhanced" "Detected in some" "cerebral cortex: 1.2;white matter: 1.1" "Group enriched" "Detected in some" 110 "memory B-cell: 8.3;naive B-cell: 13.6" "Lineage enriched" "Detected in single" 137 "B-cells: 13.6" "Cancer enriched" "Detected in single" 97 "lymphoma: 18.4" "Breast - Plasma cells, Minor Salivary Gland - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 21: Non-specific - Metabolism" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 67: Plasma cells - Plasma cell differentiation" "unprognostic (3.03e-3)" "unprognostic (2.33e-3)" "unprognostic (3.67e-2)" "unprognostic (4.89e-1)" "unprognostic (1.40e-1)" "potential prognostic favorable (9.14e-4)" "unprognostic (1.06e-1)" "unprognostic (3.58e-1)" "unprognostic (2.22e-2)" "unprognostic (3.66e-1)" "unprognostic (2.32e-1)" "unprognostic (1.50e-2)" "unprognostic (5.09e-2)" "unprognostic (7.47e-2)" "unprognostic (3.19e-1)" "unprognostic (3.27e-1)" "unprognostic (1.78e-1)" "unprognostic (5.96e-2)" "unprognostic (1.97e-1)" "unprognostic (3.63e-1)" "unprognostic (2.81e-1)" "unprognostic (7.99e-2)" "unprognostic (2.30e-1)" "unprognostic (5.29e-1)" IGHV7-81 ENSG00000211979 "Immunoglobulin heavy variable 7-81 (non-functional)" A0A0B4J1V7 14 106874583-106875071 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 11.8;lymphoid tissue: 17.1;stomach 1: 11.6" "Group enriched" "Detected in some" 12 "Gastric chief cells: 1.1;Plasma cells: 1.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 57.5" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "memory B-cell: 5.5;naive B-cell: 4.0" "Lineage enriched" "Detected in single" 14 "B-cells: 5.5" "Cancer enhanced" "Detected in some" "lymphoma: 8.1;Rhabdoid: 3.8" "Breast - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 44: Plasma cells - Antibody production & secretion" "unprognostic (6.13e-3)" "unprognostic (1.58e-2)" "unprognostic (1.70e-1)" "unprognostic (1.33e-1)" "unprognostic (5.53e-2)" "potential prognostic favorable (5.07e-4)" "unprognostic (3.22e-1)" "unprognostic (9.95e-2)" "unprognostic (2.08e-2)" "unprognostic (8.80e-2)" "unprognostic (3.56e-1)" "unprognostic (1.14e-2)" "unprognostic (3.64e-2)" "unprognostic (2.92e-2)" "unprognostic (2.29e-1)" "potential prognostic favorable (7.13e-4)" "unprognostic (4.50e-1)" "unprognostic (9.59e-2)" "unprognostic (8.27e-2)" "unprognostic (8.95e-2)" "unprognostic (1.16e-1)" "unprognostic (1.29e-1)" "unprognostic (4.22e-1)" "unprognostic (1.22e-1)" "unprognostic (1.09e-1)" IGHV8-51-1 "IGHV(III)-51-1, IGHVIII-51-1" ENSG00000254167 "Immunoglobulin heavy variable IGHV8-51-1 (non-functional)" 14 106583501-106583807 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 6 "lymphoid tissue: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "Leukemia: 3.3" "Breast - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 80: Thymus - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" IGIP "C5orf53, LOC492311" ENSG00000182700 "IgA inducing protein" A6NJ69 5 140125937-140129392 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 44.2" "Cell type enhanced" "Detected in many" "Lactotrophs: 33.8;Thyrotrophs: 33.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "HPA041877, HPA048615" Uncertain Approved Vesicles "Secreted to blood" "No annotated function" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 1 Vesicles "HPA041877: , HPA048615: " "unprognostic (9.90e-3)" "unprognostic (1.55e-2)" "unprognostic (2.58e-2)" "unprognostic (1.23e-2)" "unprognostic (1.03e-1)" "unprognostic (3.77e-1)" "unprognostic (1.11e-1)" "unprognostic (2.42e-2)" "unprognostic (6.65e-2)" "validated prognostic favorable (1.22e-7)" "validated prognostic favorable (3.60e-4)" "potential prognostic favorable (1.56e-5)" "unprognostic (1.08e-1)" "unprognostic (1.65e-1)" "unprognostic (1.16e-1)" "unprognostic (5.36e-2)" "unprognostic (1.45e-1)" "unprognostic (2.63e-2)" "unprognostic (3.55e-2)" "unprognostic (3.95e-3)" "unprognostic (3.46e-2)" "unprognostic (3.69e-1)" "unprognostic (3.47e-1)" "unprognostic (6.72e-2)" "unprognostic (2.89e-1)" "unprognostic (4.74e-2)" "unprognostic (1.83e-1)" "unprognostic (4.61e-2)" "unprognostic (4.31e-2)" IGKC HCAK1 ENSG00000211592 "Immunoglobulin kappa constant" 2 88857161-88857683 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "intestine: 32939.3;lymphoid tissue: 58910.1;urinary bladder: 23289.0" "Cell type enriched" "Detected in some" 22 "Plasma cells: 2433.8" "Cell type enriched" "Detected in single" 12 "leukocyte: 1.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 21 "memory B-cell: 39309.6;naive B-cell: 35339.2" "Lineage enriched" "Detected in all" 23 "B-cells: 39309.6" "Cancer enriched" "Detected in many" 6 "Myeloma: 27290.2" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB015377, HPA041235" Uncertain Approved Vesicles,Cytosol "Immunoglobulin genes" NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 67: Plasma cells - Plasma cell differentiation" "Vesicles, Cytosol" "CAB015377: , HPA041235: " "unprognostic (7.72e-3)" "potential prognostic favorable (3.27e-4)" "unprognostic (1.01e-1)" "unprognostic (1.21e-1)" "unprognostic (2.70e-1)" "unprognostic (1.18e-2)" "unprognostic (2.70e-1)" "potential prognostic favorable (4.66e-4)" "unprognostic (1.55e-1)" "potential prognostic unfavorable (5.19e-4)" "unprognostic (1.06e-1)" "unprognostic (5.59e-3)" "unprognostic (6.46e-2)" "unprognostic (1.50e-2)" "unprognostic (3.75e-3)" "unprognostic (1.66e-1)" "unprognostic (5.63e-2)" "unprognostic (1.90e-2)" "unprognostic (3.60e-2)" "unprognostic (1.36e-1)" "unprognostic (5.26e-3)" "unprognostic (4.54e-1)" "unprognostic (1.98e-2)" "unprognostic (1.42e-1)" "unprognostic (5.62e-2)" "unprognostic (1.43e-1)" "unprognostic (1.46e-1)" "unprognostic (8.67e-2)" "unprognostic (8.35e-2)" IGKJ1 J1 ENSG00000211597 "Immunoglobulin kappa joining 1" A0A0A0MT89 2 88861886-88861923 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "intestine: 2904.4;lymphoid tissue: 3132.4;salivary gland: 1166.2;stomach 1: 2293.1;urinary bladder: 1051.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 418 "memory B-cell: 38195.4;naive B-cell: 32246.9;plasmacytoid DC: 14819.2" "Group enriched" "Detected in all" 390 "B-cells: 38195.4;dendritic cells: 14819.2" "Group enriched" "Detected in many" 20 "lymphoma: 636.4;Myeloma: 2236.6" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 20: Myeloma - Immune response" "unprognostic (2.96e-2)" "potential prognostic favorable (1.76e-6)" "unprognostic (1.64e-1)" "unprognostic (2.68e-1)" "unprognostic (1.00e-1)" "potential prognostic unfavorable (2.05e-4)" "potential prognostic favorable (1.03e-4)" "unprognostic (4.23e-1)" "unprognostic (2.48e-2)" "unprognostic (2.79e-2)" "unprognostic (9.04e-2)" "unprognostic (1.11e-1)" "unprognostic (9.23e-3)" "unprognostic (1.56e-2)" "unprognostic (3.98e-1)" "unprognostic (1.08e-1)" "unprognostic (1.97e-2)" "unprognostic (2.49e-1)" "unprognostic (3.84e-1)" "unprognostic (3.74e-2)" "unprognostic (2.27e-2)" "unprognostic (8.92e-2)" "unprognostic (6.00e-2)" "unprognostic (2.57e-1)" "unprognostic (2.43e-1)" "unprognostic (3.64e-1)" IGKJ2 J2 ENSG00000211596 "Immunoglobulin kappa joining 2" 2 88861525-88861563 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 2532.2;lymphoid tissue: 1802.3;salivary gland: 1138.7;stomach 1: 1382.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 50 "memory B-cell: 22116.4;naive B-cell: 20711.8" "Lineage enriched" "Detected in all" 51 "B-cells: 22116.4" "Group enriched" "Detected in some" 10 "lymphoma: 264.8;Myeloma: 231.2" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 18: Non-specific - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "unprognostic (3.10e-2)" "potential prognostic favorable (1.37e-4)" "unprognostic (6.36e-2)" "unprognostic (1.76e-1)" "unprognostic (1.12e-1)" "unprognostic (3.01e-2)" "unprognostic (1.70e-3)" "unprognostic (3.81e-1)" "unprognostic (2.99e-2)" "unprognostic (4.27e-1)" "unprognostic (4.11e-1)" "unprognostic (1.91e-1)" "unprognostic (7.64e-2)" "unprognostic (1.42e-2)" "unprognostic (3.67e-1)" "unprognostic (2.01e-1)" "unprognostic (5.81e-2)" "unprognostic (3.13e-1)" "unprognostic (2.92e-1)" "unprognostic (7.43e-3)" "unprognostic (3.60e-1)" "unprognostic (2.26e-1)" "unprognostic (2.78e-1)" "unprognostic (1.95e-1)" "unprognostic (1.11e-1)" "unprognostic (3.50e-1)" IGKJ3 ENSG00000211595 "Immunoglobulin kappa joining 3" 2 88861221-88861258 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 952.4;lymphoid tissue: 840.1;stomach 1: 600.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 12 "spinal cord: 41.4" "Group enriched" "Detected in all" 25 "memory B-cell: 8634.6;naive B-cell: 7168.1" "Lineage enriched" "Detected in all" 28 "B-cells: 8634.6" "Group enriched" "Detected in some" 18 "lymphoma: 228.3;Myeloma: 454.5" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 7: Non-specific - Ribosome" "Cluster 51: Myeloma - Immunoglobulins" "unprognostic (1.70e-1)" "potential prognostic favorable (7.61e-6)" "unprognostic (1.69e-1)" "unprognostic (1.51e-1)" "unprognostic (1.32e-1)" "unprognostic (1.19e-2)" "unprognostic (4.69e-1)" "potential prognostic favorable (9.14e-4)" "unprognostic (5.14e-2)" "unprognostic (4.84e-2)" "unprognostic (4.51e-1)" "unprognostic (2.21e-1)" "unprognostic (1.33e-2)" "unprognostic (2.55e-1)" "unprognostic (3.61e-1)" "unprognostic (1.75e-1)" "unprognostic (8.01e-3)" "unprognostic (8.09e-2)" "unprognostic (6.03e-2)" "unprognostic (5.53e-2)" "unprognostic (7.66e-2)" "unprognostic (1.11e-1)" "unprognostic (2.57e-1)" "unprognostic (3.18e-1)" "unprognostic (1.68e-1)" "unprognostic (3.29e-1)" IGKJ4 ENSG00000211594 "Immunoglobulin kappa joining 4" 2 88860886-88860922 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 3075.9;lymphoid tissue: 2780.6;stomach 1: 1888.0" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 5258.9" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 42 "memory B-cell: 36351.4;naive B-cell: 27786.4" "Lineage enriched" "Detected in all" 48 "B-cells: 36351.4" "Cancer enriched" "Detected in many" 9 "Myeloma: 3755.6" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "unprognostic (1.06e-1)" "unprognostic (2.09e-3)" "unprognostic (3.41e-2)" "unprognostic (1.90e-1)" "unprognostic (2.13e-1)" "unprognostic (2.40e-3)" "unprognostic (2.78e-1)" "unprognostic (1.14e-3)" "unprognostic (3.99e-1)" "unprognostic (2.75e-2)" "unprognostic (2.44e-1)" "unprognostic (1.24e-1)" "unprognostic (1.46e-1)" "unprognostic (9.78e-3)" "unprognostic (6.80e-3)" "unprognostic (3.17e-1)" "unprognostic (2.28e-1)" "unprognostic (7.73e-3)" "unprognostic (1.52e-1)" "unprognostic (1.86e-1)" "unprognostic (3.45e-2)" "unprognostic (9.22e-2)" "unprognostic (5.10e-2)" "unprognostic (1.02e-1)" "unprognostic (2.80e-1)" "unprognostic (1.66e-1)" "unprognostic (1.72e-1)" IGKJ5 ENSG00000211593 "Immunoglobulin kappa joining 5" 2 88860568-88860605 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 4 "intestine: 1150.9;lymphoid tissue: 1297.5;salivary gland: 622.9;stomach 1: 889.3;urinary bladder: 418.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "spinal cord: 10.2" "Group enriched" "Detected in all" 24 "memory B-cell: 9209.6;naive B-cell: 8763.4" "Lineage enriched" "Detected in all" 25 "B-cells: 9209.6" "Group enriched" "Detected in some" 12 "lymphoma: 273.2;Myeloma: 381.9" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "unprognostic (1.08e-1)" "potential prognostic favorable (9.44e-4)" "unprognostic (2.02e-1)" "unprognostic (1.63e-1)" "unprognostic (1.62e-1)" "unprognostic (1.24e-2)" "unprognostic (4.03e-1)" "potential prognostic favorable (2.45e-4)" "unprognostic (8.73e-1)" "unprognostic (8.16e-2)" "unprognostic (1.82e-2)" "unprognostic (1.49e-1)" "unprognostic (1.88e-1)" "unprognostic (1.32e-1)" "unprognostic (6.60e-2)" "unprognostic (3.18e-1)" "unprognostic (1.78e-1)" "unprognostic (1.02e-2)" "unprognostic (4.63e-1)" "unprognostic (2.32e-1)" "unprognostic (3.29e-2)" "unprognostic (1.78e-1)" "unprognostic (1.16e-1)" "unprognostic (7.80e-3)" "unprognostic (7.37e-2)" "unprognostic (3.59e-1)" "unprognostic (2.14e-1)" IGKV1-12 "IGKV112, L19" ENSG00000243290 "Immunoglobulin kappa variable 1-12" A0A0C4DH73 2 89040224-89040745 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 369.7;lymphoid tissue: 736.1" "Cell type enriched" "Detected in some" 7 "Plasma cells: 47.7" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 820 "memory B-cell: 261.0;naive B-cell: 165.1" "Lineage enriched" "Detected in single" 1004 "B-cells: 261.0" "Cancer enhanced" "Detected in single" "Myeloma: 2.7" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" HPA048721 Approved "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 22: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 78: Plasma cells - Antibody production & ER-stress response" "HPA048721: " "unprognostic (3.51e-2)" "potential prognostic favorable (5.72e-5)" "unprognostic (6.09e-3)" "unprognostic (7.76e-2)" "unprognostic (4.40e-1)" "potential prognostic unfavorable (2.97e-4)" "unprognostic (4.42e-2)" "potential prognostic favorable (7.45e-4)" "unprognostic (3.56e-3)" "unprognostic (1.57e-2)" "potential prognostic unfavorable (2.14e-4)" "unprognostic (2.51e-1)" "unprognostic (4.26e-2)" "unprognostic (1.67e-2)" "unprognostic (2.25e-1)" "unprognostic (1.65e-1)" "unprognostic (4.19e-2)" "unprognostic (3.23e-1)" "unprognostic (1.85e-1)" "unprognostic (3.28e-2)" "unprognostic (3.86e-1)" "unprognostic (9.00e-3)" "unprognostic (3.36e-1)" "unprognostic (8.99e-2)" "unprognostic (8.60e-2)" "unprognostic (3.41e-1)" "unprognostic (2.89e-1)" "unprognostic (2.68e-1)" IGKV1-16 "IGKV116, L1" ENSG00000240864 "Immunoglobulin kappa variable 1-16" P04430 2 89099859-89100361 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 261.3;lymphoid tissue: 557.2;urinary bladder: 244.3" "Group enriched" "Detected in some" 4 "Gastric chief cells: 2.2;Plasma cells: 8.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "choroid plexus: 1.3" "Group enriched" "Detected in some" 522 "memory B-cell: 165.4;naive B-cell: 113.5" "Lineage enriched" "Detected in single" 619 "B-cells: 165.4" "Cancer enriched" "Detected in some" 44 "Myeloma: 129.4" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" HPA048721 Approved "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 36: Choroid plexus - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 78: Plasma cells - Antibody production & ER-stress response" "HPA048721: " "unprognostic (5.33e-3)" "potential prognostic favorable (2.40e-5)" "unprognostic (1.31e-2)" "unprognostic (7.19e-2)" "unprognostic (2.90e-1)" "unprognostic (2.71e-3)" "unprognostic (3.69e-1)" "potential prognostic favorable (5.40e-4)" "unprognostic (5.84e-2)" "unprognostic (2.35e-2)" "unprognostic (4.96e-3)" "unprognostic (9.63e-2)" "unprognostic (6.48e-2)" "unprognostic (9.24e-2)" "unprognostic (4.50e-2)" "unprognostic (1.97e-1)" "unprognostic (1.01e-1)" "unprognostic (2.72e-1)" "unprognostic (6.18e-2)" "unprognostic (1.87e-2)" "unprognostic (4.24e-1)" "unprognostic (8.40e-3)" "unprognostic (4.00e-1)" "unprognostic (8.66e-2)" "unprognostic (2.60e-1)" "unprognostic (1.77e-1)" "unprognostic (2.85e-2)" "unprognostic (1.64e-1)" IGKV1-17 "A30, IGKV117" ENSG00000240382 "Immunoglobulin kappa variable 1-17" P01599 2 89117342-89117844 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 350.2;lymphoid tissue: 423.1" "Cell type enhanced" "Detected in some" "Gastric chief cells: 2.2;Parietal cells: 3.5;Plasma cells: 9.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 426 "memory B-cell: 106.2;naive B-cell: 82.7" "Lineage enriched" "Detected in single" 479 "B-cells: 106.2" "Not detected" "Not detected" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" HPA048721 Approved "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 78: Plasma cells - Antibody production & ER-stress response" "HPA048721: " "unprognostic (8.63e-2)" "unprognostic (4.09e-3)" "unprognostic (7.32e-2)" "unprognostic (3.50e-2)" "unprognostic (2.11e-1)" "unprognostic (1.83e-2)" "unprognostic (4.90e-1)" "potential prognostic favorable (1.79e-4)" "unprognostic (5.96e-1)" "unprognostic (1.47e-3)" "unprognostic (9.62e-2)" "unprognostic (8.99e-3)" "unprognostic (3.42e-2)" "unprognostic (2.05e-2)" "unprognostic (2.00e-1)" "unprognostic (5.14e-2)" "unprognostic (1.62e-1)" "unprognostic (6.82e-2)" "unprognostic (2.57e-1)" "unprognostic (2.97e-2)" "unprognostic (8.36e-3)" "unprognostic (2.57e-1)" "unprognostic (2.05e-2)" "unprognostic (8.80e-2)" "unprognostic (2.00e-1)" "unprognostic (8.08e-3)" "unprognostic (1.29e-1)" "unprognostic (3.22e-1)" "unprognostic (2.21e-1)" IGKV1-27 "A20, IGKV127" ENSG00000244575 "Immunoglobulin kappa variable 1-27" A0A075B6S5 2 89213423-89213928 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 250.5;lymphoid tissue: 323.9;salivary gland: 171.4" "Group enriched" "Detected in some" 6 "Parietal cells: 3.5;Plasma cells: 11.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 683 "memory B-cell: 153.5;naive B-cell: 186.6" "Lineage enriched" "Detected in single" 749 "B-cells: 186.6" "Cancer enriched" "Detected in single" 482 "lymphoma: 158.0" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" HPA048721 Approved "Immunoglobulin genes" Immunity NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 78: Plasma cells - Antibody production & ER-stress response" "HPA048721: " "unprognostic (2.32e-1)" "potential prognostic favorable (7.34e-7)" "unprognostic (9.42e-3)" "unprognostic (3.48e-2)" "unprognostic (9.50e-2)" "unprognostic (2.36e-2)" "unprognostic (7.69e-2)" "potential prognostic favorable (4.56e-4)" "unprognostic (2.76e-2)" "unprognostic (1.01e-1)" "potential prognostic unfavorable (4.70e-4)" "unprognostic (4.21e-2)" "unprognostic (9.27e-2)" "unprognostic (4.63e-2)" "unprognostic (3.02e-1)" "unprognostic (9.63e-2)" "unprognostic (4.00e-2)" "unprognostic (3.61e-1)" "unprognostic (8.84e-2)" "unprognostic (1.59e-3)" "unprognostic (9.15e-2)" "unprognostic (3.87e-2)" "unprognostic (2.27e-1)" "unprognostic (3.06e-1)" "unprognostic (2.51e-2)" "unprognostic (2.35e-1)" "unprognostic (2.27e-1)" "unprognostic (2.52e-1)" IGKV1-33 "IGKV133, O18" ENSG00000242076 "Immunoglobulin kappa variable 1-33" P01594 2 89268001-89268506 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Bence-Jones protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1605.6;stomach 1: 585.3;urinary bladder: 570.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 7 "spinal cord: 20.3" "Group enriched" "Detected in some" 366 "memory B-cell: 367.8;naive B-cell: 427.7" "Lineage enriched" "Detected in many" 394 "B-cells: 427.7" "Group enriched" "Detected in some" 145 "lymphoma: 168.4;Myeloma: 47.8" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" HPA048721 Approved "Immunoglobulin genes" Immunity NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 7: Non-specific - Ribosome" "Cluster 55: Lymphoma - Immune response" "HPA048721: " "unprognostic (1.53e-1)" "unprognostic (8.48e-3)" "unprognostic (5.36e-3)" "unprognostic (8.69e-2)" "unprognostic (1.57e-2)" "unprognostic (2.02e-3)" "potential prognostic favorable (1.21e-4)" "unprognostic (1.13e-1)" "unprognostic (1.94e-3)" "unprognostic (1.11e-1)" "potential prognostic unfavorable (1.69e-4)" "unprognostic (1.77e-1)" "unprognostic (2.14e-2)" "unprognostic (1.62e-2)" "unprognostic (8.93e-2)" "unprognostic (2.17e-1)" "unprognostic (2.92e-2)" "unprognostic (5.04e-1)" "unprognostic (1.50e-1)" "unprognostic (5.51e-2)" "unprognostic (5.07e-2)" "unprognostic (1.41e-2)" "unprognostic (3.69e-3)" "unprognostic (2.57e-1)" "unprognostic (1.19e-1)" "unprognostic (1.29e-1)" "unprognostic (1.76e-1)" "unprognostic (5.73e-2)" IGKV1-37 "IGKV137, O14" ENSG00000239862 "Immunoglobulin kappa variable 1-37 (non-functional)" A0A075B6S9 2 89297264-89297785 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 7.7;lymphoid tissue: 16.1;urinary bladder: 5.2" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 7.2" "Not detected" "Not detected" "Group enriched" "Detected in some" 249 "memory B-cell: 21.3;naive B-cell: 28.3" "Lineage enriched" "Detected in single" 284 "B-cells: 28.3" "Group enriched" "Detected in some" 21 "lymphoma: 1.8;Myeloma: 2.3" "Adipose visceral - Plasma cells, Breast - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Prostate - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" HPA048721 Approved "Immunoglobulin genes" Immunity NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 51: Myeloma - Immunoglobulins" "HPA048721: " "potential prognostic favorable (1.19e-4)" "unprognostic (2.07e-1)" "unprognostic (2.52e-2)" "potential prognostic favorable (4.04e-5)" "unprognostic (7.40e-2)" "unprognostic (2.52e-3)" "unprognostic (4.29e-1)" "unprognostic (8.23e-2)" "unprognostic (2.96e-1)" "unprognostic (2.06e-1)" "unprognostic (6.30e-2)" "unprognostic (4.49e-1)" "unprognostic (3.70e-2)" "unprognostic (4.13e-1)" IGKV1-39 ENSG00000242371 "Immunoglobulin kappa variable 1-39" P01597 2 89319625-89320146 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 92.4;lymphoid tissue: 191.6;salivary gland: 98.2;stomach 1: 78.0" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 387 "memory B-cell: 1074.8;naive B-cell: 941.5" "Lineage enriched" "Detected in many" 413 "B-cells: 1074.8" "Cancer enriched" "Detected in some" 9 "Myeloma: 134.5" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" HPA048721 Approved "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 5: Spleen - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "HPA048721: " "unprognostic (2.84e-1)" "unprognostic (3.33e-3)" "unprognostic (1.13e-1)" "unprognostic (3.77e-2)" "unprognostic (2.97e-1)" "unprognostic (1.97e-1)" "potential prognostic favorable (2.93e-5)" "unprognostic (8.55e-2)" "unprognostic (2.04e-1)" "unprognostic (3.65e-3)" "unprognostic (1.43e-1)" "unprognostic (2.25e-2)" "unprognostic (1.89e-2)" "unprognostic (2.65e-2)" "unprognostic (1.30e-1)" "unprognostic (1.38e-2)" "unprognostic (3.69e-1)" "unprognostic (1.29e-1)" "unprognostic (2.79e-1)" "unprognostic (7.02e-1)" "unprognostic (1.08e-1)" "unprognostic (2.39e-1)" "unprognostic (2.79e-1)" "unprognostic (1.90e-1)" "unprognostic (4.81e-2)" "unprognostic (3.18e-1)" "unprognostic (5.62e-2)" IGKV1-5 ENSG00000243466 "Immunoglobulin kappa variable 1-5" P01602 2 88947301-88947957 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 727.5;lymphoid tissue: 1363.4;urinary bladder: 887.2" "Cell type enriched" "Detected in some" 10 "Plasma cells: 164.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 364 "memory B-cell: 862.6;naive B-cell: 866.9" "Lineage enriched" "Detected in many" 365 "B-cells: 866.9" "Cancer enriched" "Detected in some" 8 "Myeloma: 751.6" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" HPA048721 Approved "Immunoglobulin genes" Immunity NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 78: Plasma cells - Antibody production & ER-stress response" "HPA048721: " "unprognostic (1.44e-2)" "potential prognostic favorable (3.61e-5)" "unprognostic (1.96e-1)" "unprognostic (7.22e-2)" "unprognostic (1.64e-1)" "unprognostic (2.66e-3)" "unprognostic (1.85e-1)" "potential prognostic favorable (5.94e-4)" "unprognostic (3.57e-1)" "unprognostic (1.09e-2)" "unprognostic (4.69e-2)" "unprognostic (1.14e-3)" "unprognostic (6.80e-2)" "unprognostic (3.41e-2)" "unprognostic (4.82e-3)" "unprognostic (8.56e-2)" "unprognostic (5.51e-2)" "unprognostic (1.07e-1)" "unprognostic (2.84e-1)" "unprognostic (3.17e-1)" "unprognostic (1.14e-3)" "unprognostic (1.94e-1)" "unprognostic (6.24e-3)" "unprognostic (1.59e-1)" "unprognostic (2.38e-1)" "unprognostic (8.58e-2)" "unprognostic (1.20e-1)" "unprognostic (1.13e-1)" "unprognostic (8.27e-3)" IGKV1-6 ENSG00000239855 "Immunoglobulin kappa variable 1-6" A0A0C4DH72 2 88966262-88966767 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 145.3;lymphoid tissue: 564.7" "Cell type enriched" "Detected in single" 85 "Plasma cells: 30.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Lung Squamous Cell Carcinoma (TCGA): 158.8" "Not detected" "Not detected" "Group enriched" "Detected in some" 805 "memory B-cell: 124.1;naive B-cell: 86.4" "Lineage enriched" "Detected in single" 949 "B-cells: 124.1" "Group enriched" "Detected in some" 25 "lymphoma: 3.8;Myeloma: 1.2" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" HPA048721 Approved "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 78: Plasma cells - Antibody production & ER-stress response" "HPA048721: " "unprognostic (7.20e-2)" "potential prognostic favorable (8.13e-6)" "unprognostic (2.38e-3)" "unprognostic (7.21e-2)" "unprognostic (2.66e-1)" "potential prognostic favorable (5.72e-4)" "unprognostic (4.65e-1)" "unprognostic (1.66e-2)" "unprognostic (1.82e-1)" "unprognostic (1.22e-2)" "unprognostic (1.73e-2)" "unprognostic (1.75e-1)" "unprognostic (4.10e-1)" "unprognostic (9.41e-2)" "unprognostic (6.23e-2)" "unprognostic (8.16e-2)" "unprognostic (2.46e-1)" "unprognostic (7.14e-2)" "unprognostic (1.43e-1)" "unprognostic (2.72e-1)" "unprognostic (1.73e-1)" "unprognostic (1.10e-1)" "unprognostic (6.72e-2)" "unprognostic (8.91e-3)" "unprognostic (2.58e-1)" "unprognostic (1.29e-1)" "unprognostic (2.00e-1)" IGKV1-8 "IGKV18, L9" ENSG00000240671 "Immunoglobulin kappa variable 1-8" A0A0C4DH67 2 88992409-88992931 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 27.7;lymphoid tissue: 51.3;salivary gland: 21.1;stomach 1: 17.5;urinary bladder: 39.1" "Cell type enriched" "Detected in single" 17 "Plasma cells: 5.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 313 "memory B-cell: 131.7;naive B-cell: 137.1" "Lineage enriched" "Detected in single" 319 "B-cells: 137.1" "Not detected" "Not detected" "Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" HPA048721 Approved "Immunoglobulin genes" Immunity NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 44: Plasma cells - Antibody production & secretion" "HPA048721: " "unprognostic (2.97e-1)" "unprognostic (3.76e-3)" "unprognostic (7.59e-3)" "unprognostic (1.45e-1)" "unprognostic (4.06e-1)" "unprognostic (1.60e-3)" "unprognostic (2.85e-1)" "unprognostic (4.32e-3)" "potential prognostic unfavorable (5.45e-4)" "unprognostic (3.86e-1)" "potential prognostic favorable (2.97e-4)" "unprognostic (1.30e-1)" "unprognostic (5.80e-2)" "unprognostic (1.49e-1)" "unprognostic (4.73e-2)" "unprognostic (7.69e-2)" "unprognostic (1.33e-1)" "unprognostic (9.43e-2)" "unprognostic (5.52e-2)" "unprognostic (2.65e-2)" "unprognostic (2.49e-1)" "unprognostic (8.04e-2)" "unprognostic (3.74e-2)" "unprognostic (2.73e-1)" "unprognostic (1.11e-1)" "unprognostic (1.13e-1)" IGKV1-9 "IGKV19, L8" ENSG00000241755 "Immunoglobulin kappa variable 1-9" A0A0C4DH69 2 89009982-89010515 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 400.0;lymphoid tissue: 626.1;stomach 1: 266.7" "Group enriched" "Detected in some" 5 "Gastric chief cells: 10.9;Parietal cells: 8.8;Plasma cells: 32.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Lung Squamous Cell Carcinoma (TCGA): 280.2" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 706 "memory B-cell: 301.9;naive B-cell: 299.3" "Lineage enriched" "Detected in single" 709 "B-cells: 301.9" "Cancer enriched" "Detected in single" 6 "lymphoma: 3.1" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" HPA048721 Approved "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 78: Plasma cells - Antibody production & ER-stress response" "HPA048721: " "unprognostic (1.98e-3)" "potential prognostic favorable (2.09e-8)" "unprognostic (5.41e-3)" "unprognostic (1.30e-1)" "unprognostic (1.32e-2)" "potential prognostic unfavorable (3.10e-4)" "unprognostic (1.04e-1)" "potential prognostic favorable (4.97e-4)" "unprognostic (6.81e-2)" "unprognostic (3.95e-3)" "unprognostic (2.79e-1)" "unprognostic (5.64e-3)" "unprognostic (7.14e-2)" "unprognostic (1.21e-1)" "unprognostic (5.81e-2)" "unprognostic (1.88e-1)" "unprognostic (1.83e-1)" "unprognostic (5.61e-2)" "unprognostic (1.33e-1)" "unprognostic (7.78e-2)" "unprognostic (1.77e-2)" "unprognostic (1.51e-1)" "unprognostic (4.37e-2)" "unprognostic (2.29e-1)" "unprognostic (5.53e-2)" "unprognostic (1.94e-2)" "unprognostic (1.02e-1)" "unprognostic (2.05e-1)" "unprognostic (1.30e-1)" IGKV1D-12 ENSG00000278857 "Immunoglobulin kappa variable 1D-12" P01611 2 90159840-90160335 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 27.4;lymphoid tissue: 44.6;salivary gland: 34.3" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rectum Adenocarcinoma (TCGA): 27.3" "Not detected" "Not detected" "Group enriched" "Detected in some" 33 "memory B-cell: 13.0;naive B-cell: 12.3" "Lineage enriched" "Detected in single" 34 "B-cells: 13.0" "Not detected" "Not detected" "Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" HPA048721 Approved "Immunoglobulin genes" Immunity NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 5: Spleen - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 108: Fibroblasts - ECM organization" "HPA048721: " "unprognostic (9.24e-3)" "unprognostic (4.05e-1)" "unprognostic (9.94e-2)" "unprognostic (1.53e-1)" "potential prognostic favorable (6.19e-4)" "unprognostic (1.02e-2)" "unprognostic (1.90e-2)" "unprognostic (2.42e-1)" "unprognostic (1.90e-1)" "unprognostic (3.94e-1)" "unprognostic (4.10e-1)" "unprognostic (1.53e-2)" "unprognostic (7.58e-2)" "unprognostic (6.90e-2)" "unprognostic (4.78e-1)" IGKV1D-13 ENSG00000276566 "Immunoglobulin kappa variable 1D-13" "A0A0B4J2D9, P0DP09" 2 90154073-90154574 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 97.4;lymphoid tissue: 297.3" "Group enriched" "Detected in some" 4 "Late spermatids: 9.8;Plasma cells: 16.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 736 "memory B-cell: 482.6;naive B-cell: 333.8" "Lineage enriched" "Detected in single" 870 "B-cells: 482.6" "Cancer enriched" "Detected in single" 32 "Myeloma: 22.3" "Adrenal gland - Plasma cells, Breast - Plasma cells, Kidney - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" HPA048721 Approved "Immunoglobulin genes" Immunity NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 44: Plasma cells - Antibody production & secretion" "HPA048721: " "unprognostic (6.51e-2)" "potential prognostic favorable (1.03e-6)" "unprognostic (3.63e-3)" "unprognostic (3.15e-1)" "unprognostic (2.20e-1)" "unprognostic (1.26e-1)" "unprognostic (1.11e-3)" "unprognostic (7.27e-2)" "unprognostic (5.71e-3)" "unprognostic (7.38e-3)" "unprognostic (2.83e-1)" "unprognostic (4.75e-3)" "unprognostic (1.90e-1)" "unprognostic (4.64e-1)" "unprognostic (5.30e-1)" "unprognostic (5.99e-2)" "unprognostic (2.14e-1)" "unprognostic (5.04e-1)" "unprognostic (1.17e-1)" "unprognostic (6.04e-2)" "unprognostic (4.62e-2)" "unprognostic (8.30e-2)" "unprognostic (8.12e-2)" "unprognostic (3.42e-1)" "unprognostic (2.05e-1)" IGKV1D-16 ENSG00000241244 "Immunoglobulin kappa variable 1D-16" P01601 2 90100236-90100738 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 74.3;intestine: 86.0;lymphoid tissue: 154.2" "Group enriched" "Detected in some" 4 "Gastric chief cells: 1.1;Plasma cells: 2.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 62.5" "Not detected" "Not detected" "Group enriched" "Detected in some" 328 "memory B-cell: 57.9;naive B-cell: 121.3" "Lineage enriched" "Detected in single" 444 "B-cells: 121.3" "Not detected" "Not detected" "Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" HPA048721 Approved "Immunoglobulin genes" Immunity NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 44: Plasma cells - Antibody production & secretion" "HPA048721: " "unprognostic (1.75e-1)" "unprognostic (1.86e-3)" "unprognostic (7.13e-2)" "unprognostic (6.91e-2)" "unprognostic (3.99e-2)" "unprognostic (1.10e-2)" "unprognostic (6.60e-2)" "unprognostic (1.90e-1)" "unprognostic (1.72e-1)" "unprognostic (3.36e-3)" "unprognostic (5.74e-2)" "unprognostic (6.88e-2)" "unprognostic (5.29e-2)" "unprognostic (7.77e-2)" "unprognostic (1.14e-1)" "unprognostic (1.08e-2)" "unprognostic (3.00e-1)" "unprognostic (2.88e-2)" "potential prognostic favorable (5.21e-4)" "unprognostic (3.54e-1)" "unprognostic (1.30e-1)" "unprognostic (2.99e-1)" "unprognostic (1.12e-1)" "unprognostic (3.90e-1)" "unprognostic (2.73e-1)" "unprognostic (6.94e-2)" "unprognostic (2.39e-1)" IGKV1D-17 ENSG00000242766 "Immunoglobulin kappa variable 1D-17" A0A075B6S4 2 90082635-90083291 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 6.7;lymphoid tissue: 11.0;salivary gland: 5.4" "Cell type enriched" "Detected in single" 61 "Plasma cells: 15.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 60 "memory B-cell: 7.7;naive B-cell: 4.1" "Lineage enriched" "Detected in single" 78 "B-cells: 7.7" "Group enriched" "Detected in some" 7 "Gallbladder cancer: 1.0;Myeloma: 1.2" "Breast - Plasma cells, Minor Salivary Gland - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" HPA048721 Approved "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 5: Spleen - Immune response" "Cluster 24: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 44: Plasma cells - Antibody production & secretion" "HPA048721: " "unprognostic (4.55e-1)" "unprognostic (1.08e-3)" "unprognostic (1.55e-1)" "unprognostic (1.27e-2)" "unprognostic (2.32e-1)" "unprognostic (2.42e-2)" "unprognostic (5.56e-2)" "unprognostic (9.82e-2)" "unprognostic (4.37e-2)" "unprognostic (8.12e-3)" "unprognostic (7.26e-2)" "unprognostic (2.85e-1)" "unprognostic (1.32e-1)" "unprognostic (3.81e-1)" "unprognostic (2.26e-1)" "unprognostic (3.28e-1)" "unprognostic (1.69e-1)" "unprognostic (2.89e-1)" "unprognostic (2.46e-2)" "unprognostic (1.27e-1)" "unprognostic (3.48e-1)" IGKV1D-33 ENSG00000239975 "Immunoglobulin kappa variable 1D-33" P01593 2 89913982-89914545 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 33.8;lung: 16.1;lymphoid tissue: 60.7;salivary gland: 63.1;stomach 1: 21.5" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 10.3;Stomach Adenocarcinoma (TCGA): 10.3" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "memory B-cell: 2.7" "Lineage enriched" "Detected in single" 27 "B-cells: 2.7" "Cancer enhanced" "Detected in single" "lymphoma: 2.4" "Adipose visceral - Plasma cells, Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" HPA048721 Approved "Immunoglobulin genes" Immunity NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 5: Spleen - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 44: Plasma cells - Antibody production & secretion" "HPA048721: " "unprognostic (1.03e-2)" "unprognostic (1.73e-1)" "unprognostic (4.74e-3)" "potential prognostic favorable (9.63e-5)" "unprognostic (2.92e-1)" "unprognostic (1.91e-2)" "unprognostic (1.52e-2)" "unprognostic (3.06e-1)" "unprognostic (5.88e-2)" "unprognostic (1.75e-2)" "unprognostic (1.03e-1)" "unprognostic (4.56e-2)" "unprognostic (1.22e-1)" IGKV1D-37 "IGKV1D37, O4" ENSG00000250036 "Immunoglobulin kappa variable 1D-37 (non-functional)" P0DSN7 2 89884740-89885216 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 11.9;stomach 1: 14.2;urinary bladder: 18.9" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Lung Squamous Cell Carcinoma (TCGA): 10.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 208 "memory B-cell: 13.7;naive B-cell: 29.2" "Lineage enriched" "Detected in single" 283 "B-cells: 29.2" "Cancer enriched" "Detected in some" 75 "Myeloma: 260.3" "Breast - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" HPA048721 Approved "Immunoglobulin genes" Immunity NA NA "Cluster 34: B-cells - Unknown function" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 51: Myeloma - Immunoglobulins" "HPA048721: " "unprognostic (1.70e-2)" "unprognostic (4.91e-2)" "unprognostic (1.83e-1)" "unprognostic (1.57e-1)" "unprognostic (2.23e-3)" "unprognostic (2.39e-1)" "unprognostic (8.68e-3)" "unprognostic (2.75e-2)" "unprognostic (8.03e-2)" "unprognostic (1.26e-1)" "unprognostic (3.64e-1)" "unprognostic (4.84e-3)" "unprognostic (3.51e-2)" "unprognostic (1.52e-1)" "unprognostic (1.93e-1)" "unprognostic (3.09e-1)" "unprognostic (1.27e-1)" "unprognostic (5.29e-1)" IGKV1D-39 ENSG00000251546 "Immunoglobulin kappa variable 1D-39" P04432 2 89862482-89862981 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 2729.5;lymphoid tissue: 6055.0;stomach 1: 2126.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 224 "memory B-cell: 473.3;naive B-cell: 736.4" "Lineage enriched" "Detected in many" 273 "B-cells: 736.4" "Cancer enriched" "Detected in many" 18 "Myeloma: 5094.4" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" HPA048721 Approved "Immunoglobulin genes" Immunity NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 44: Plasma cells - Antibody production & secretion" "HPA048721: " "unprognostic (2.65e-2)" "potential prognostic favorable (3.58e-4)" "unprognostic (1.65e-2)" "unprognostic (1.12e-1)" "unprognostic (3.99e-1)" "unprognostic (1.14e-2)" "unprognostic (2.62e-1)" "potential prognostic favorable (2.58e-5)" "unprognostic (2.34e-1)" "unprognostic (1.88e-2)" "unprognostic (1.06e-1)" "potential prognostic unfavorable (3.73e-4)" "unprognostic (9.68e-2)" "unprognostic (1.26e-1)" "unprognostic (2.33e-2)" "unprognostic (5.84e-2)" "unprognostic (2.03e-1)" "unprognostic (1.36e-2)" "unprognostic (2.50e-1)" "unprognostic (2.15e-1)" "unprognostic (3.75e-3)" "unprognostic (4.28e-2)" "unprognostic (1.36e-1)" "unprognostic (2.11e-1)" "unprognostic (2.86e-2)" "unprognostic (6.03e-2)" "unprognostic (1.23e-1)" "unprognostic (2.49e-1)" "unprognostic (3.17e-2)" IGKV1D-42 ENSG00000211633 "Immunoglobulin kappa variable 1D-42 (non-functional)" A0A075B6H8 2 90190193-90190681 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 44.5;lymphoid tissue: 23.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 37 "memory B-cell: 5.6;naive B-cell: 1.6" "Lineage enriched" "Detected in single" 57 "B-cells: 5.6" "Not detected" "Not detected" "Breast - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" HPA048721 Approved "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 44: Plasma cells - Antibody production & secretion" "HPA048721: " "potential prognostic favorable (4.99e-5)" "unprognostic (2.25e-2)" "unprognostic (6.50e-2)" "unprognostic (3.61e-1)" "unprognostic (2.18e-3)" "unprognostic (1.09e-1)" "unprognostic (2.31e-2)" "unprognostic (1.03e-1)" "unprognostic (1.59e-1)" "unprognostic (2.19e-3)" "unprognostic (2.84e-2)" "unprognostic (3.02e-2)" "unprognostic (1.38e-1)" "unprognostic (1.26e-1)" "unprognostic (1.82e-1)" "unprognostic (2.03e-2)" "unprognostic (2.50e-1)" "unprognostic (4.83e-1)" IGKV1D-43 ENSG00000242580 "Immunoglobulin kappa variable 1D-43" A0A0B4J1Z2 2 90209873-90210529 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 2.7;lymphoid tissue: 4.5;stomach 1: 3.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 153 "memory B-cell: 13.3;naive B-cell: 17.1" "Lineage enriched" "Detected in single" 171 "B-cells: 17.1" "Cancer enhanced" "Detected in single" "Myeloma: 2.3" "Breast - Plasma cells, Kidney - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" HPA048721 Approved "Immunoglobulin genes" Immunity NA NA "Cluster 18: Non-specific - Translation" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 67: Plasma cells - Plasma cell differentiation" "HPA048721: " "unprognostic (3.33e-1)" "unprognostic (2.67e-2)" "unprognostic (4.37e-1)" "potential prognostic favorable (1.04e-4)" "unprognostic (3.04e-2)" "unprognostic (1.68e-2)" "unprognostic (1.91e-1)" "unprognostic (4.53e-2)" "unprognostic (1.25e-1)" "unprognostic (1.17e-1)" "unprognostic (7.08e-2)" "unprognostic (7.00e-2)" IGKV1D-8 ENSG00000239819 "Immunoglobulin kappa variable 1D-8" A0A087WSZ0 2 90220727-90221384 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 4.3;lymphoid tissue: 13.3;salivary gland: 5.2" "Cell type enhanced" "Detected in single" "Thymic myoid cells: 1.4" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "Testicular Germ Cell Tumor (TCGA): 10.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 324 "memory B-cell: 32.9;naive B-cell: 31.9" "Lineage enriched" "Detected in single" 329 "B-cells: 32.9" "Group enriched" "Detected in some" 14 "lymphoma: 1.5;Myeloma: 1.1" "Adipose visceral - Plasma cells, Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" HPA048721 Approved "Immunoglobulin genes" Immunity NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 44: Plasma cells - Antibody production & secretion" "HPA048721: " "unprognostic (5.22e-1)" "unprognostic (3.15e-2)" "unprognostic (2.28e-1)" "unprognostic (1.23e-1)" "unprognostic (1.66e-1)" "unprognostic (3.41e-2)" "unprognostic (2.01e-1)" "unprognostic (2.87e-1)" "unprognostic (4.43e-1)" "unprognostic (2.54e-2)" "unprognostic (3.97e-1)" "unprognostic (2.20e-1)" "unprognostic (1.91e-1)" "unprognostic (1.22e-1)" IGKV1OR2-108 "IGKV1/OR2-108, IGKV1OR2108, IGO1" ENSG00000231292 "Immunoglobulin kappa variable 1/OR2-108 (non-functional)" 2 113406396-113406872 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 35.7;lymphoid tissue: 52.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 6 "choroid plexus: 11.6" "Group enriched" "Detected in some" 55 "memory B-cell: 13.6;naive B-cell: 12.3" "Lineage enriched" "Detected in single" 58 "B-cells: 13.6" "Cancer enhanced" "Detected in many" "Myeloma: 5.1" "Breast - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Prostate - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "hypothalamus: 6.1;midbrain: 16.3;spinal cord: 15.1" HPA048721 Approved NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 36: Choroid plexus - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 44: Plasma cells - Antibody production & secretion" "HPA048721: " "unprognostic (6.10e-2)" "potential prognostic favorable (3.70e-6)" "unprognostic (7.12e-2)" "unprognostic (1.09e-1)" "unprognostic (4.43e-2)" "unprognostic (1.43e-3)" "unprognostic (6.53e-3)" "unprognostic (4.45e-2)" "potential prognostic unfavorable (2.71e-4)" "unprognostic (6.31e-2)" "unprognostic (2.56e-3)" "unprognostic (4.18e-2)" "unprognostic (1.66e-2)" "unprognostic (7.52e-2)" "unprognostic (1.28e-1)" "unprognostic (3.22e-2)" "unprognostic (5.40e-1)" "unprognostic (1.22e-1)" "unprognostic (1.41e-1)" "unprognostic (2.76e-1)" "unprognostic (5.17e-2)" "unprognostic (2.01e-1)" "unprognostic (1.33e-1)" "unprognostic (5.13e-1)" IGKV2-24 ENSG00000241294 "Immunoglobulin kappa variable 2-24" A0A0C4DH68 2 89176328-89177160 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 255.0;lymphoid tissue: 461.5;urinary bladder: 879.0" "Cell type enriched" "Detected in single" 13 "Plasma cells: 1.4" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 4 "memory B-cell: 48.3" "Lineage enriched" "Detected in single" 484 "B-cells: 48.3" "Cancer enriched" "Detected in single" 4 "lymphoma: 1.2" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 22: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 44: Plasma cells - Antibody production & secretion" "unprognostic (3.04e-2)" "potential prognostic favorable (5.03e-7)" "unprognostic (1.42e-2)" "unprognostic (3.66e-2)" "unprognostic (3.62e-1)" "unprognostic (1.90e-1)" "potential prognostic favorable (1.11e-4)" "unprognostic (4.73e-2)" "unprognostic (2.04e-1)" "potential prognostic unfavorable (2.90e-4)" "unprognostic (2.46e-2)" "unprognostic (1.28e-1)" "unprognostic (9.85e-2)" "unprognostic (2.13e-3)" "unprognostic (2.81e-2)" "unprognostic (5.11e-2)" "unprognostic (2.51e-1)" "unprognostic (7.12e-2)" "unprognostic (8.57e-3)" "unprognostic (3.53e-1)" "unprognostic (4.39e-2)" "unprognostic (4.76e-1)" "unprognostic (2.38e-1)" "unprognostic (1.83e-1)" "unprognostic (2.97e-1)" "unprognostic (9.59e-2)" "unprognostic (2.64e-1)" IGKV2-28 ENSG00000244116 "Immunoglobulin kappa variable 2-28" A0A075B6P5 2 89221698-89222461 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1022.0;lymphoid tissue: 1670.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 14 "naive B-cell: 41.1" "Lineage enriched" "Detected in many" 39 "B-cells: 41.1" "Cancer enriched" "Detected in single" 247 "lymphoma: 221.9" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 34: B-cells - Unknown function" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "unprognostic (1.62e-1)" "potential prognostic favorable (4.22e-4)" "unprognostic (1.34e-2)" "unprognostic (5.58e-2)" "unprognostic (4.59e-1)" "potential prognostic unfavorable (7.36e-5)" "unprognostic (1.88e-1)" "potential prognostic favorable (3.57e-5)" "unprognostic (5.17e-2)" "unprognostic (3.09e-3)" "unprognostic (2.50e-1)" "potential prognostic unfavorable (1.97e-4)" "unprognostic (1.26e-1)" "unprognostic (6.42e-3)" "unprognostic (4.44e-2)" "unprognostic (1.55e-1)" "unprognostic (7.73e-2)" "unprognostic (2.86e-2)" "unprognostic (1.17e-1)" "unprognostic (2.39e-1)" "unprognostic (1.52e-2)" "unprognostic (1.99e-1)" "unprognostic (1.40e-1)" "unprognostic (1.96e-1)" "unprognostic (4.79e-2)" "unprognostic (1.54e-1)" "unprognostic (3.03e-1)" "unprognostic (7.61e-2)" "unprognostic (8.66e-2)" IGKV2-30 ENSG00000243238 "Immunoglobulin kappa variable 2-30" P06310 2 89244781-89245596 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 590.1;lymphoid tissue: 627.0;stomach 1: 303.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 315 "memory B-cell: 561.8;naive B-cell: 326.0" "Lineage enriched" "Detected in many" 398 "B-cells: 561.8" "Cancer enriched" "Detected in some" 11 "lymphoma: 288.4" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 102: Non-specific - Mixed function" "unprognostic (1.97e-2)" "potential prognostic favorable (9.06e-6)" "unprognostic (1.13e-3)" "unprognostic (2.58e-2)" "unprognostic (2.73e-1)" "potential prognostic unfavorable (8.99e-4)" "unprognostic (1.59e-1)" "potential prognostic favorable (3.49e-5)" "unprognostic (4.52e-2)" "unprognostic (1.19e-1)" "unprognostic (1.17e-3)" "unprognostic (1.65e-2)" "unprognostic (6.35e-2)" "unprognostic (5.48e-3)" "unprognostic (3.11e-2)" "unprognostic (5.56e-2)" "unprognostic (3.04e-2)" "unprognostic (3.80e-1)" "unprognostic (8.04e-2)" "potential prognostic favorable (2.43e-4)" "unprognostic (2.02e-1)" "unprognostic (2.42e-2)" "unprognostic (3.42e-1)" "unprognostic (7.71e-2)" "unprognostic (3.37e-1)" "unprognostic (3.85e-1)" "unprognostic (1.23e-1)" "unprognostic (2.01e-1)" IGKV2-40 ENSG00000273962 "Immunoglobulin kappa variable 2-40" A0A087WW87 2 89330116-89330429 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 39.9;lymphoid tissue: 30.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 42 "memory B-cell: 3.2;naive B-cell: 5.1" "Lineage enriched" "Detected in single" 51 "B-cells: 5.1" "Not detected" "Not detected" "Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Prostate - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 5: Spleen - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "potential prognostic favorable (5.92e-5)" "unprognostic (1.38e-1)" "unprognostic (4.01e-2)" "unprognostic (5.60e-2)" "unprognostic (1.28e-3)" "unprognostic (3.77e-1)" "unprognostic (2.20e-1)" "unprognostic (2.50e-2)" "unprognostic (2.86e-3)" "unprognostic (1.15e-1)" "unprognostic (1.78e-2)" "unprognostic (4.36e-3)" "unprognostic (9.85e-2)" "unprognostic (6.88e-3)" "unprognostic (9.99e-3)" "unprognostic (3.19e-2)" "unprognostic (4.97e-2)" "unprognostic (4.31e-1)" "unprognostic (2.97e-1)" "unprognostic (4.17e-1)" IGKV2D-24 ENSG00000241566 "Immunoglobulin kappa variable 2D-24 (non-functional)" A0A075B6R9 2 90004797-90005629 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 18.4;lymphoid tissue: 30.0;urinary bladder: 14.3" "Cell type enriched" "Detected in single" 34 "Plasma cells: 3.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Lung Squamous Cell Carcinoma (TCGA): 12.4" "Group enriched" "Detected in some" 8 "cerebral cortex: 1.4;hippocampal formation: 3.8" "Group enriched" "Detected in some" 48 "memory B-cell: 6.8;naive B-cell: 2.7" "Lineage enriched" "Detected in single" 68 "B-cells: 6.8" "Cancer enriched" "Detected in single" 5 "lymphoma: 1.7" "Adipose visceral - Plasma cells, Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 29: Forebrain - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 44: Plasma cells - Antibody production & secretion" "unprognostic (2.20e-1)" "potential prognostic favorable (1.43e-4)" "unprognostic (8.22e-2)" "unprognostic (4.86e-2)" "unprognostic (1.02e-1)" "unprognostic (1.18e-3)" "unprognostic (2.21e-1)" "unprognostic (2.73e-2)" "unprognostic (3.00e-1)" "unprognostic (5.22e-1)" "unprognostic (3.15e-2)" "unprognostic (5.47e-2)" "unprognostic (3.21e-1)" "unprognostic (2.10e-1)" "unprognostic (1.22e-1)" "unprognostic (3.56e-1)" "unprognostic (4.40e-2)" "unprognostic (4.98e-1)" "unprognostic (2.57e-2)" IGKV2D-26 ENSG00000211623 "Immunoglobulin kappa variable 2D-26" A0A0A0MRZ7 2 89985922-89986702 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 4.3;lymphoid tissue: 5.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in single" "hippocampal formation: 1.1" "Group enriched" "Detected in some" 246 "memory B-cell: 21.9;naive B-cell: 27.3" "Lineage enriched" "Detected in single" 273 "B-cells: 27.3" "Cancer enriched" "Detected in single" 19 "lymphoma: 1.8" "Breast - Plasma cells, Minor Salivary Gland - Plasma cells, Stomach - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 34: B-cells - Unknown function" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 29: Forebrain - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 67: Plasma cells - Plasma cell differentiation" "unprognostic (2.95e-2)" "unprognostic (1.31e-1)" "unprognostic (2.35e-3)" "unprognostic (2.52e-1)" "unprognostic (2.46e-1)" "unprognostic (3.41e-1)" "unprognostic (2.88e-1)" IGKV2D-28 ENSG00000242534 "Immunoglobulin kappa variable 2D-28" P01615 2 89959979-89960748 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 141.3;lymphoid tissue: 384.1;salivary gland: 209.7" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Stomach Adenocarcinoma (TCGA): 310.5" "Region enhanced" "Detected in single" "medulla oblongata: 1.3" "Group enriched" "Detected in many" 221 "memory B-cell: 2988.8;naive B-cell: 2094.9" "Lineage enriched" "Detected in all" 260 "B-cells: 2988.8" "Cancer enriched" "Detected in single" 43 "lymphoma: 42.9" "Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Prostate - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 5: Spleen - Immune response" "Cluster 29: Forebrain - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 78: Plasma cells - Antibody production & ER-stress response" "unprognostic (2.81e-1)" "unprognostic (1.18e-2)" "unprognostic (1.96e-2)" "unprognostic (2.34e-1)" "unprognostic (1.45e-1)" "unprognostic (2.38e-1)" "unprognostic (7.39e-2)" "potential prognostic favorable (1.63e-5)" "unprognostic (4.83e-2)" "unprognostic (7.18e-2)" "unprognostic (3.49e-2)" "unprognostic (1.59e-1)" "unprognostic (9.35e-2)" "unprognostic (9.16e-3)" "unprognostic (1.20e-1)" "unprognostic (1.04e-1)" "unprognostic (1.47e-2)" "unprognostic (4.00e-1)" "unprognostic (9.94e-2)" "unprognostic (2.36e-1)" "unprognostic (1.88e-1)" "unprognostic (1.29e-2)" "unprognostic (5.76e-2)" "unprognostic (1.23e-1)" "unprognostic (1.86e-1)" "unprognostic (2.66e-1)" "unprognostic (7.09e-2)" "unprognostic (4.47e-1)" IGKV2D-29 ENSG00000243264 "Immunoglobulin kappa variable 2D-29" A0A075B6S2 2 89947512-89948269 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 234.5;lymphoid tissue: 432.7" "Cell type enriched" "Detected in some" 30 "Plasma cells: 35.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 261 "memory B-cell: 356.8;naive B-cell: 487.7" "Lineage enriched" "Detected in many" 302 "B-cells: 487.7" "Group enriched" "Detected in some" 23 "lymphoma: 5.8;Myeloma: 2.4" "Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 78: Plasma cells - Antibody production & ER-stress response" "unprognostic (6.78e-2)" "potential prognostic favorable (3.86e-5)" "potential prognostic favorable (9.54e-4)" "unprognostic (2.19e-2)" "unprognostic (2.77e-1)" "unprognostic (2.97e-3)" "unprognostic (2.73e-1)" "unprognostic (7.75e-2)" "unprognostic (2.23e-1)" "unprognostic (7.72e-3)" "potential prognostic favorable (5.34e-4)" "unprognostic (2.62e-2)" "unprognostic (7.31e-3)" "unprognostic (3.42e-1)" "unprognostic (9.68e-2)" "unprognostic (2.68e-2)" "unprognostic (2.09e-1)" "unprognostic (1.48e-1)" "unprognostic (5.42e-3)" "unprognostic (1.78e-1)" "unprognostic (5.82e-2)" "unprognostic (4.56e-1)" "unprognostic (3.35e-1)" "unprognostic (1.49e-1)" "unprognostic (3.31e-1)" "unprognostic (3.03e-1)" "unprognostic (2.15e-1)" IGKV2D-30 ENSG00000239571 "Immunoglobulin kappa variable 2D-30" A0A075B6S6 2 89936859-89937679 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 14.3;lymphoid tissue: 31.3;stomach 1: 20.9" "Cell type enriched" "Detected in single" 33 "Plasma cells: 4.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 376 "memory B-cell: 124.5;naive B-cell: 164.2" "Lineage enriched" "Detected in single" 428 "B-cells: 164.2" "Cancer enriched" "Detected in single" 86 "lymphoma: 35.7" "Adipose visceral - Plasma cells, Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Prostate - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 44: Plasma cells - Antibody production & secretion" "unprognostic (6.58e-1)" "unprognostic (3.87e-3)" "unprognostic (3.30e-3)" "unprognostic (2.41e-1)" "unprognostic (4.54e-2)" "unprognostic (3.43e-3)" "unprognostic (2.03e-1)" "unprognostic (1.56e-1)" "unprognostic (2.69e-2)" "unprognostic (1.58e-2)" "unprognostic (4.35e-2)" "unprognostic (9.49e-2)" "unprognostic (1.46e-2)" "unprognostic (3.18e-1)" "unprognostic (1.99e-1)" "unprognostic (1.43e-1)" "unprognostic (2.73e-1)" "unprognostic (2.92e-1)" IGKV2D-40 ENSG00000251039 "Immunoglobulin kappa variable 2D-40" P01614 2 89851791-89852493 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 108.6" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Lung Squamous Cell Carcinoma (TCGA): 64.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 1093 "memory B-cell: 123.2;naive B-cell: 95.2" "Lineage enriched" "Detected in single" 1233 "B-cells: 123.2" "Cancer enriched" "Detected in some" 882 "Myeloma: 2773.4" "Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Prostate - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 34: B-cells - Unknown function" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 51: Myeloma - Immunoglobulins" "unprognostic (7.68e-2)" "potential prognostic favorable (1.18e-5)" "unprognostic (1.36e-1)" "unprognostic (1.91e-2)" "unprognostic (7.54e-2)" "potential prognostic favorable (2.94e-6)" "unprognostic (4.67e-2)" "unprognostic (1.12e-1)" "unprognostic (3.84e-3)" "unprognostic (3.70e-2)" "unprognostic (6.27e-2)" "potential prognostic favorable (6.53e-4)" "unprognostic (3.44e-1)" "unprognostic (1.42e-1)" "unprognostic (6.80e-2)" "unprognostic (5.44e-1)" "unprognostic (2.82e-2)" "unprognostic (1.48e-2)" "unprognostic (3.86e-1)" "unprognostic (7.86e-2)" "unprognostic (2.19e-2)" "unprognostic (1.80e-1)" "unprognostic (4.28e-2)" "unprognostic (6.80e-2)" "unprognostic (2.39e-1)" "unprognostic (5.49e-1)" IGKV3-11 ENSG00000241351 "Immunoglobulin kappa variable 3-11" P04433 2 89027171-89027731 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1282.2;lymphoid tissue: 2623.2;urinary bladder: 1710.9" "Cell type enhanced" "Detected in some" "Foveolar cells: 2.6;Gastric chief cells: 6.6;Mucous neck cells: 3.1;Parietal cells: 5.3;Plasma cells: 18.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 15 "spinal cord: 34.2" "Group enriched" "Detected in many" 290 "memory B-cell: 1738.3;naive B-cell: 1408.8" "Lineage enriched" "Detected in many" 321 "B-cells: 1738.3" "Cancer enriched" "Detected in some" 17 "Myeloma: 5519.7" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" HPA047702 Approved Approved "Plasma membrane,Cytosol" "Immunoglobulin genes" Immunity NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 7: Non-specific - Ribosome" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 78: Plasma cells - Antibody production & ER-stress response" "Plasma membrane, Cytosol" "HPA047702: " "unprognostic (3.27e-3)" "unprognostic (8.65e-3)" "unprognostic (6.42e-3)" "unprognostic (1.71e-1)" "unprognostic (4.86e-2)" "unprognostic (1.74e-2)" "unprognostic (2.29e-1)" "potential prognostic favorable (6.14e-5)" "unprognostic (2.57e-1)" "unprognostic (4.94e-3)" "unprognostic (4.83e-1)" "unprognostic (1.11e-3)" "unprognostic (2.56e-1)" "unprognostic (3.43e-2)" "unprognostic (3.18e-2)" "unprognostic (4.22e-2)" "unprognostic (1.31e-1)" "unprognostic (1.22e-1)" "unprognostic (2.86e-1)" "unprognostic (1.24e-1)" "potential prognostic favorable (1.84e-4)" "unprognostic (3.25e-1)" "unprognostic (6.67e-3)" "unprognostic (2.90e-2)" "unprognostic (3.88e-2)" "unprognostic (1.37e-2)" "unprognostic (1.76e-1)" "unprognostic (3.58e-1)" "unprognostic (1.45e-1)" IGKV3-15 ENSG00000244437 "Immunoglobulin kappa variable 3-15" P01624 2 89085177-89085787 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 734.7;lymphoid tissue: 1863.5;urinary bladder: 737.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 562 "memory B-cell: 2253.6;naive B-cell: 1663.0" "Lineage enriched" "Detected in all" 646 "B-cells: 2253.6" "Cancer enriched" "Detected in some" 37 "Myeloma: 745.1" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" HPA047702 Approved Approved "Plasma membrane,Cytosol" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 22: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Plasma membrane, Cytosol" "HPA047702: " "unprognostic (2.83e-2)" "unprognostic (1.40e-3)" "unprognostic (2.48e-2)" "unprognostic (1.24e-1)" "unprognostic (1.04e-1)" "potential prognostic unfavorable (4.17e-5)" "unprognostic (1.30e-1)" "unprognostic (1.61e-3)" "unprognostic (1.80e-1)" "unprognostic (2.59e-3)" "unprognostic (7.70e-2)" "unprognostic (4.78e-2)" "unprognostic (6.36e-2)" "unprognostic (2.87e-2)" "potential prognostic favorable (9.54e-4)" "unprognostic (1.49e-1)" "unprognostic (6.59e-2)" "unprognostic (1.38e-2)" "unprognostic (1.19e-1)" "unprognostic (9.73e-2)" "unprognostic (2.12e-2)" "unprognostic (4.32e-1)" "unprognostic (3.95e-2)" "unprognostic (4.74e-2)" "unprognostic (2.60e-1)" "unprognostic (1.65e-1)" "unprognostic (2.15e-1)" "unprognostic (1.92e-1)" "unprognostic (3.51e-1)" IGKV3-20 ENSG00000239951 "Immunoglobulin kappa variable 3-20" P01619 2 89142574-89143160 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 2877.1;lymphoid tissue: 4893.1" "Cell type enriched" "Detected in some" 5 "Plasma cells: 57.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "spinal cord: 17.6" "Group enriched" "Detected in many" 327 "memory B-cell: 1609.9;naive B-cell: 1229.8" "Lineage enriched" "Detected in many" 370 "B-cells: 1609.9" "Group enriched" "Detected in many" 367 "lymphoma: 353.5;Myeloma: 1322.2" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" HPA047702 Approved Approved "Plasma membrane,Cytosol" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 20: Myeloma - Immune response" "Cluster 78: Plasma cells - Antibody production & ER-stress response" "Plasma membrane, Cytosol" "HPA047702: " "unprognostic (1.24e-1)" "potential prognostic favorable (8.23e-5)" "unprognostic (1.17e-2)" "unprognostic (6.22e-2)" "unprognostic (8.91e-2)" "unprognostic (1.65e-2)" "unprognostic (1.88e-1)" "unprognostic (2.00e-3)" "unprognostic (2.59e-1)" "unprognostic (2.04e-2)" "unprognostic (1.79e-1)" "potential prognostic unfavorable (6.94e-4)" "unprognostic (1.34e-1)" "unprognostic (6.55e-2)" "unprognostic (4.69e-2)" "unprognostic (2.17e-1)" "unprognostic (9.18e-2)" "unprognostic (1.47e-2)" "unprognostic (2.41e-1)" "unprognostic (1.22e-1)" "unprognostic (1.02e-2)" "unprognostic (1.57e-1)" "unprognostic (6.56e-2)" "unprognostic (1.39e-1)" "unprognostic (2.24e-2)" "unprognostic (4.84e-2)" "unprognostic (1.67e-1)" "unprognostic (5.75e-2)" "unprognostic (2.90e-1)" IGKV3-7 ENSG00000243063 "Immunoglobulin kappa variable 3-7 (non-functional)" A0A075B6H7 2 88978468-88979081 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 17.4;lymphoid tissue: 20.7;salivary gland: 15.0;stomach 1: 9.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 61 "memory B-cell: 28.0;naive B-cell: 24.5" "Lineage enriched" "Detected in single" 65 "B-cells: 28.0" "Cancer enriched" "Detected in single" 48 "Myeloma: 27.2" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" HPA047702 Approved Approved "Plasma membrane,Cytosol" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 51: Myeloma - Immunoglobulins" "Plasma membrane, Cytosol" "HPA047702: " "unprognostic (1.99e-1)" "potential prognostic favorable (5.56e-4)" "unprognostic (5.32e-3)" "unprognostic (1.19e-1)" "unprognostic (3.74e-2)" "unprognostic (3.87e-3)" "unprognostic (5.66e-2)" "unprognostic (1.24e-1)" "potential prognostic unfavorable (5.65e-4)" "unprognostic (1.53e-2)" "unprognostic (1.88e-2)" "unprognostic (1.77e-1)" "unprognostic (1.79e-2)" "unprognostic (9.65e-2)" "unprognostic (1.20e-1)" "unprognostic (7.50e-2)" "unprognostic (9.04e-2)" "unprognostic (1.74e-1)" "unprognostic (1.95e-2)" "unprognostic (2.29e-1)" "unprognostic (1.06e-1)" "unprognostic (3.15e-1)" IGKV3D-11 ENSG00000211632 "Immunoglobulin kappa variable 3D-11" A0A0A0MRZ8 2 90172802-90173414 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 36.1;lymphoid tissue: 54.6;stomach 1: 26.1" "Cell type enriched" "Detected in some" 6 "Plasma cells: 6.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 469 "memory B-cell: 153.1;naive B-cell: 147.2" "Lineage enriched" "Detected in single" 479 "B-cells: 153.1" "Cancer enriched" "Detected in some" 317 "Myeloma: 396.6" "Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" HPA047702 Approved Approved "Plasma membrane,Cytosol" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 44: Plasma cells - Antibody production & secretion" "Plasma membrane, Cytosol" "HPA047702: " "unprognostic (5.53e-2)" "potential prognostic favorable (1.25e-4)" "unprognostic (1.42e-3)" "unprognostic (3.02e-2)" "unprognostic (3.72e-1)" "potential prognostic favorable (2.70e-4)" "unprognostic (2.62e-2)" "unprognostic (7.99e-2)" "unprognostic (1.01e-3)" "unprognostic (3.97e-1)" "unprognostic (1.83e-2)" "unprognostic (8.55e-2)" "unprognostic (2.35e-1)" "unprognostic (3.26e-3)" "unprognostic (4.06e-2)" "unprognostic (9.06e-2)" "unprognostic (1.83e-1)" "unprognostic (2.38e-2)" "unprognostic (1.20e-1)" "unprognostic (1.59e-2)" "unprognostic (2.21e-1)" "unprognostic (5.40e-1)" "unprognostic (9.14e-2)" "unprognostic (3.62e-1)" "unprognostic (2.17e-1)" "unprognostic (1.54e-2)" IGKV3D-15 ENSG00000224041 "Immunoglobulin kappa variable 3D-15" A0A087WSY6 2 90114838-90115402 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 118.4;lymphoid tissue: 189.0;salivary gland: 50.8;stomach 1: 82.0;urinary bladder: 54.5" "Cell type enriched" "Detected in single" 22 "Plasma cells: 2.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 190 "memory B-cell: 181.9;naive B-cell: 156.7" "Lineage enriched" "Detected in single" 204 "B-cells: 181.9" "Cancer enriched" "Detected in some" 42 "Myeloma: 3660.7" "Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" HPA047702 Approved Approved "Plasma membrane,Cytosol" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 44: Plasma cells - Antibody production & secretion" "Plasma membrane, Cytosol" "HPA047702: " "unprognostic (5.09e-2)" "potential prognostic favorable (3.90e-5)" "unprognostic (5.70e-2)" "unprognostic (1.09e-1)" "unprognostic (6.18e-2)" "unprognostic (5.61e-2)" "potential prognostic favorable (4.94e-4)" "unprognostic (2.31e-1)" "unprognostic (2.56e-3)" "unprognostic (1.33e-2)" "unprognostic (3.87e-3)" "unprognostic (3.65e-3)" "unprognostic (4.91e-2)" "unprognostic (1.96e-2)" "unprognostic (3.28e-1)" "unprognostic (2.04e-2)" "unprognostic (9.63e-2)" "unprognostic (2.07e-1)" "unprognostic (7.65e-2)" "unprognostic (6.00e-3)" "unprognostic (2.50e-1)" "unprognostic (1.72e-1)" "unprognostic (7.49e-3)" "unprognostic (3.05e-1)" "unprognostic (8.98e-2)" "unprognostic (2.42e-1)" "unprognostic (1.64e-1)" "unprognostic (4.01e-1)" IGKV3D-20 ENSG00000211625 "Immunoglobulin kappa variable 3D-20" A0A0C4DH25 2 90038848-90039479 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 123.2;lymphoid tissue: 257.3" "Cell type enhanced" "Detected in some" "Foveolar cells: 2.4;Gastric chief cells: 4.4;Parietal cells: 1.8;Plasma cells: 13.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebral cortex: 1.1" "Group enriched" "Detected in some" 1034 "memory B-cell: 198.1;naive B-cell: 99.4" "Lineage enriched" "Detected in single" 1377 "B-cells: 198.1" "Cancer enriched" "Detected in some" 711 "Myeloma: 2737.4" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" HPA047702 Approved Approved "Plasma membrane,Cytosol" "Immunoglobulin genes" Immunity NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 78: Plasma cells - Antibody production & ER-stress response" "Plasma membrane, Cytosol" "HPA047702: " "potential prognostic favorable (8.91e-4)" "unprognostic (1.94e-3)" "unprognostic (7.91e-2)" "unprognostic (9.32e-2)" "unprognostic (1.33e-1)" "unprognostic (2.78e-3)" "unprognostic (4.19e-1)" "unprognostic (6.12e-3)" "unprognostic (2.57e-2)" "unprognostic (2.01e-2)" "unprognostic (2.71e-1)" "unprognostic (1.23e-2)" "unprognostic (7.81e-2)" "unprognostic (1.64e-1)" "unprognostic (1.97e-2)" "unprognostic (1.21e-1)" "unprognostic (7.10e-2)" "unprognostic (2.44e-1)" "unprognostic (1.36e-3)" "unprognostic (1.07e-1)" "unprognostic (9.32e-2)" "unprognostic (1.70e-1)" "unprognostic (8.76e-2)" "unprognostic (4.53e-2)" "unprognostic (3.52e-1)" "unprognostic (8.47e-2)" "unprognostic (3.99e-1)" IGKV3D-7 ENSG00000228325 "Immunoglobulin kappa variable 3D-7" A0A0C4DH55 2 90234812-90235370 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 4.3;lymphoid tissue: 5.2;stomach 1: 4.2;urinary bladder: 5.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 37 "memory B-cell: 2.9;naive B-cell: 4.4" "Lineage enriched" "Detected in single" 44 "B-cells: 4.4" "Group enriched" "Detected in some" 24 "lymphoma: 2.6;Myeloma: 3.7" "Adipose visceral - Plasma cells, Breast - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Prostate - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" HPA047702 Approved Approved "Plasma membrane,Cytosol" "Immunoglobulin genes" Immunity NA NA "Cluster 34: B-cells - Unknown function" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 55: Lymphoma - Immune response" "Plasma membrane, Cytosol" "HPA047702: " "unprognostic (1.97e-1)" "unprognostic (5.35e-3)" "unprognostic (8.03e-2)" "unprognostic (1.01e-2)" "unprognostic (1.39e-1)" "unprognostic (3.75e-1)" "unprognostic (3.01e-1)" IGKV3OR2-268 "IGKV268, IGKV3/OR2-268, IGKV3/OR2-268A, IGKV3OR2-268A" ENSG00000233999 "Immunoglobulin kappa variable 3/OR2-268 (non-functional)" 2 87338511-87339035 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 93.9;lymphoid tissue: 79.8" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 5 "memory B-cell: 221.3;naive B-cell: 79.4" "Lineage enriched" "Detected in many" 7 "B-cells: 221.3" "Group enriched" "Detected in some" 53 "lymphoma: 35.4;Myeloma: 40.1" "Breast - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" HPA047702 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 51: Neurons - Mixed function" "Cluster 20: Myeloma - Immune response" "Cluster 67: Plasma cells - Plasma cell differentiation" "Plasma membrane, Cytosol" "HPA047702: " "unprognostic (7.86e-2)" "potential prognostic favorable (1.56e-4)" "unprognostic (2.81e-3)" "unprognostic (2.64e-1)" "unprognostic (3.50e-2)" "potential prognostic favorable (5.32e-4)" "unprognostic (1.99e-2)" "unprognostic (4.18e-2)" "unprognostic (1.88e-2)" "unprognostic (2.63e-1)" "unprognostic (1.34e-2)" "unprognostic (3.52e-3)" "unprognostic (2.30e-2)" "unprognostic (4.37e-2)" "unprognostic (7.17e-2)" "unprognostic (6.21e-2)" "unprognostic (5.77e-2)" "unprognostic (1.77e-1)" "unprognostic (4.80e-2)" "unprognostic (1.80e-1)" "unprognostic (1.38e-1)" "unprognostic (1.28e-1)" "unprognostic (2.72e-1)" "unprognostic (1.03e-1)" "unprognostic (6.90e-3)" IGKV4-1 "B3, IGKV41" ENSG00000211598 "Immunoglobulin kappa variable 4-1" P06312 2 88885397-88886153 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1690.4;lymphoid tissue: 2960.8" "Cell type enriched" "Detected in some" 40 "Plasma cells: 892.7" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 2591.6" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 590 "memory B-cell: 3048.7;naive B-cell: 3092.7" "Lineage enriched" "Detected in all" 595 "B-cells: 3092.7" "Cancer enriched" "Detected in some" 11 "lymphoma: 582.0" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Not detected" "Not detected" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 78: Plasma cells - Antibody production & ER-stress response" "unprognostic (1.40e-2)" "potential prognostic favorable (2.30e-4)" "unprognostic (1.86e-1)" "unprognostic (3.54e-2)" "unprognostic (8.33e-2)" "unprognostic (4.76e-3)" "unprognostic (2.30e-1)" "potential prognostic favorable (8.42e-4)" "unprognostic (1.11e-1)" "unprognostic (9.95e-2)" "unprognostic (3.74e-1)" "unprognostic (1.76e-3)" "unprognostic (2.97e-2)" "unprognostic (1.09e-2)" "unprognostic (4.32e-2)" "unprognostic (1.25e-1)" "unprognostic (1.13e-1)" "unprognostic (5.13e-3)" "unprognostic (2.57e-1)" "unprognostic (9.30e-2)" "unprognostic (3.84e-2)" "unprognostic (2.45e-1)" "unprognostic (3.81e-2)" "unprognostic (6.91e-2)" "unprognostic (1.76e-1)" "unprognostic (3.57e-1)" "unprognostic (3.83e-2)" "unprognostic (4.70e-2)" "unprognostic (3.10e-2)" IGKV5-2 "B2, IGKV52" ENSG00000211599 "Immunoglobulin kappa variable 5-2" P06315 2 88897232-88897784 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 33.6;lymphoid tissue: 77.5" "Cell type enriched" "Detected in single" 25 "Plasma cells: 2.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 22.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "memory B-cell: 21.5;naive B-cell: 17.4" "Lineage enriched" "Detected in many" 21 "B-cells: 21.5" "Cancer enriched" "Detected in single" 24 "lymphoma: 11.0" "Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Prostate - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Not detected" "Not detected" "Not detected" "Not detected" "Immunoglobulin genes" Immunity NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 78: Plasma cells - Antibody production & ER-stress response" "unprognostic (1.55e-1)" "unprognostic (2.65e-3)" "unprognostic (2.80e-2)" "unprognostic (1.10e-1)" "unprognostic (4.41e-2)" "potential prognostic favorable (6.14e-5)" "unprognostic (1.23e-3)" "unprognostic (1.18e-1)" "unprognostic (2.57e-2)" "unprognostic (1.18e-1)" "unprognostic (2.37e-2)" "unprognostic (4.66e-2)" "unprognostic (2.49e-1)" "unprognostic (1.31e-1)" "unprognostic (1.15e-1)" "unprognostic (1.10e-1)" "unprognostic (7.37e-3)" "unprognostic (1.11e-1)" "unprognostic (2.62e-1)" "unprognostic (2.28e-1)" "unprognostic (2.14e-2)" "unprognostic (4.49e-2)" "unprognostic (1.52e-1)" IGKV6-21 "A26, IGKV621" ENSG00000211611 "Immunoglobulin kappa variable 6-21 (non-functional)" A0A0C4DH24 2 89159751-89160366 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 90.9;lymphoid tissue: 131.7" "Cell type enhanced" "Detected in some" "Gastric chief cells: 2.2;Late spermatids: 1.1;Plasma cells: 1.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 195 "memory B-cell: 29.0;naive B-cell: 9.9" "Lineage enriched" "Detected in single" 290 "B-cells: 29.0" "Cancer enriched" "Detected in single" 9 "Myeloma: 1.0" "Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Testis - Late spermatids, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 20: Myeloma - Immune response" "Cluster 44: Plasma cells - Antibody production & secretion" "unprognostic (2.16e-1)" "potential prognostic favorable (8.09e-5)" "unprognostic (3.62e-2)" "unprognostic (7.29e-2)" "unprognostic (2.45e-1)" "potential prognostic favorable (3.61e-4)" "unprognostic (2.49e-2)" "unprognostic (1.21e-1)" "potential prognostic unfavorable (3.04e-4)" "unprognostic (2.25e-1)" "unprognostic (4.35e-2)" "unprognostic (4.85e-2)" "unprognostic (2.83e-1)" "unprognostic (2.74e-1)" "unprognostic (5.59e-2)" "unprognostic (6.25e-2)" "unprognostic (7.02e-2)" "unprognostic (2.02e-2)" "unprognostic (9.03e-2)" "unprognostic (7.95e-3)" "unprognostic (1.18e-1)" "unprognostic (3.50e-1)" "unprognostic (2.81e-1)" "unprognostic (1.19e-1)" "unprognostic (3.42e-1)" "unprognostic (4.18e-1)" IGKV6D-21 "A10, IGKV6D21" ENSG00000225523 "Immunoglobulin kappa variable 6D-21 (non-functional)" A0A0A0MT36 2 90021567-90022185 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 7 "intestine: 62.6;lymphoid tissue: 142.6;urinary bladder: 213.4" "Group enriched" "Detected in some" 6 "Early spermatids: 12.4;Late spermatids: 44.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Lung Squamous Cell Carcinoma (TCGA): 41.5" "Region enhanced" "Detected in single" "medulla oblongata: 1.4" "Group enriched" "Detected in some" 155 "memory B-cell: 14.2;naive B-cell: 16.6" "Lineage enriched" "Detected in single" 167 "B-cells: 16.6" "Not detected" "Not detected" "Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Prostate - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Testis - Late spermatids, Thyroid gland - Plasma cells" "Not detected" "Not detected" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" "unprognostic (6.53e-1)" "potential prognostic favorable (4.19e-6)" "unprognostic (3.44e-2)" "unprognostic (1.80e-3)" "unprognostic (1.56e-1)" "potential prognostic favorable (1.36e-5)" "unprognostic (1.43e-2)" "unprognostic (2.07e-1)" "unprognostic (4.21e-3)" "unprognostic (1.06e-1)" "unprognostic (4.91e-2)" "unprognostic (4.29e-3)" "unprognostic (1.46e-1)" "unprognostic (3.02e-1)" "unprognostic (5.69e-2)" "unprognostic (5.16e-2)" "unprognostic (1.18e-1)" "unprognostic (6.95e-2)" "unprognostic (9.98e-2)" "unprognostic (1.30e-1)" "unprognostic (1.81e-1)" "unprognostic (5.87e-1)" "unprognostic (4.09e-2)" "unprognostic (1.17e-1)" "unprognostic (9.75e-2)" "unprognostic (2.43e-1)" IGKV6D-41 ENSG00000211626 "Immunoglobulin kappa variable 6D-41 (non-functional)" A0A0C4DH26 2 90069662-90070238 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 4.4;intestine: 3.1;lymphoid tissue: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Lung Adenocarcinoma (TCGA): 1.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 40 "memory B-cell: 3.0;naive B-cell: 4.9" "Lineage enriched" "Detected in single" 49 "B-cells: 4.9" "Cancer enriched" "Detected in single" 13 "lymphoma: 1.2" "Breast - Plasma cells, Minor Salivary Gland - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 34: B-cells - Unknown function" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 44: Plasma cells - Antibody production & secretion" "unprognostic (7.83e-2)" "unprognostic (8.55e-2)" "unprognostic (3.81e-1)" "unprognostic (5.64e-1)" IGLC1 IGLC ENSG00000211675 "Immunoglobulin lambda constant 1" 22 22895375-22895834 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 3069.3;lymphoid tissue: 5228.6;stomach 1: 2196.9" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 745 "memory B-cell: 5791.3;naive B-cell: 5907.8" "Lineage enriched" "Detected in all" 752 "B-cells: 5907.8" "Cancer enriched" "Detected in many" 46 "Myeloma: 14011.1" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "unprognostic (3.06e-2)" "potential prognostic favorable (3.49e-5)" "unprognostic (1.25e-3)" "unprognostic (1.18e-1)" "unprognostic (2.24e-1)" "potential prognostic unfavorable (1.80e-4)" "potential prognostic favorable (4.22e-5)" "unprognostic (2.63e-1)" "potential prognostic unfavorable (9.24e-4)" "unprognostic (3.53e-2)" "unprognostic (3.69e-3)" "unprognostic (6.64e-2)" "unprognostic (9.06e-2)" "unprognostic (2.66e-3)" "unprognostic (1.73e-2)" "unprognostic (4.56e-2)" "unprognostic (2.67e-2)" "unprognostic (8.26e-2)" "unprognostic (9.70e-2)" "unprognostic (3.93e-3)" "unprognostic (2.89e-1)" "unprognostic (2.44e-2)" "unprognostic (3.72e-1)" "unprognostic (1.45e-1)" "unprognostic (1.24e-1)" "unprognostic (4.26e-1)" "unprognostic (6.30e-2)" "unprognostic (1.08e-1)" IGLC2 IGLC ENSG00000211677 "Immunoglobulin lambda constant 2" P0DOY2 22 22900976-22901437 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Bence-Jones protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 9136.9;lymphoid tissue: 18672.4;stomach 1: 10196.8" "Cell type enriched" "Detected in many" 9 "Plasma cells: 62189.1" "Cell type enriched" "Detected in some" 14 "leukocyte: 23.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 36 "memory B-cell: 11410.9;naive B-cell: 10729.1" "Lineage enriched" "Detected in all" 37 "B-cells: 11410.9" "Cancer enriched" "Detected in many" 10 "Myeloma: 14457.7" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 20: Myeloma - Immune response" "Cluster 67: Plasma cells - Plasma cell differentiation" "unprognostic (4.70e-2)" "potential prognostic favorable (6.65e-6)" "unprognostic (3.41e-3)" "unprognostic (8.27e-2)" "unprognostic (3.34e-1)" "unprognostic (6.09e-3)" "unprognostic (3.33e-1)" "potential prognostic favorable (2.12e-4)" "unprognostic (2.30e-1)" "unprognostic (2.13e-3)" "unprognostic (2.24e-1)" "unprognostic (1.53e-3)" "unprognostic (4.63e-2)" "unprognostic (3.05e-2)" "unprognostic (1.67e-2)" "unprognostic (6.89e-2)" "unprognostic (3.29e-2)" "unprognostic (3.10e-2)" "unprognostic (1.22e-2)" "unprognostic (1.85e-1)" "unprognostic (1.15e-2)" "unprognostic (1.20e-1)" "unprognostic (8.05e-3)" "unprognostic (2.17e-1)" "unprognostic (1.36e-1)" "unprognostic (1.31e-1)" "unprognostic (3.50e-1)" "unprognostic (1.23e-1)" "unprognostic (1.94e-2)" IGLC3 IGLC ENSG00000211679 "Immunoglobulin lambda constant 3 (Kern-Oz+ marker)" P0DOY3 22 22906342-22906803 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Bence-Jones protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 3846.9;lymphoid tissue: 7642.8;stomach 1: 3884.7;urinary bladder: 3496.7" "Cell type enriched" "Detected in some" 31 "Plasma cells: 25604.9" "Cell type enriched" "Detected in single" 245 "leukocyte: 24.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 34 "memory B-cell: 7287.2;naive B-cell: 6162.3" "Lineage enriched" "Detected in all" 37 "B-cells: 7287.2" "Cancer enriched" "Detected in many" 19 "Myeloma: 12802.2" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "CAB000050, CAB016533" Supported "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 67: Plasma cells - Plasma cell differentiation" "CAB000050: , CAB016533: " "unprognostic (1.27e-2)" "potential prognostic favorable (7.64e-5)" "unprognostic (4.45e-3)" "unprognostic (1.24e-1)" "unprognostic (1.64e-1)" "unprognostic (1.60e-2)" "unprognostic (2.07e-1)" "potential prognostic favorable (4.07e-4)" "unprognostic (2.78e-2)" "potential prognostic unfavorable (6.38e-5)" "unprognostic (7.22e-3)" "potential prognostic unfavorable (6.01e-5)" "unprognostic (5.04e-2)" "unprognostic (5.03e-3)" "unprognostic (7.16e-3)" "unprognostic (2.53e-1)" "unprognostic (4.90e-2)" "unprognostic (3.91e-2)" "unprognostic (2.92e-2)" "unprognostic (1.92e-1)" "unprognostic (2.00e-1)" "unprognostic (3.55e-1)" "unprognostic (2.07e-2)" "unprognostic (4.47e-2)" "unprognostic (8.58e-2)" "unprognostic (2.93e-2)" "unprognostic (2.57e-1)" "unprognostic (1.41e-1)" "unprognostic (1.20e-1)" IGLC7 ENSG00000211685 "Immunoglobulin lambda constant 7" 22 22922594-22923034 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 84.0;lymphoid tissue: 97.7;salivary gland: 66.5;stomach 1: 106.7" "Group enriched" "Detected in some" 11 "Foveolar cells: 225.7;Plasma cells: 773.0" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 244 "memory B-cell: 129.9;naive B-cell: 134.9" "Lineage enriched" "Detected in single" 249 "B-cells: 134.9" "Cancer enriched" "Detected in some" 24 "Myeloma: 3425.5" "Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 67: Plasma cells - Plasma cell differentiation" "unprognostic (1.08e-1)" "unprognostic (3.68e-3)" "potential prognostic favorable (1.59e-4)" "unprognostic (1.05e-1)" "unprognostic (4.97e-3)" "potential prognostic favorable (2.98e-4)" "potential prognostic unfavorable (1.68e-4)" "unprognostic (6.67e-2)" "unprognostic (7.86e-3)" "unprognostic (1.61e-1)" "unprognostic (3.91e-2)" "unprognostic (1.16e-1)" "unprognostic (4.38e-2)" "unprognostic (3.32e-2)" "unprognostic (4.40e-2)" "unprognostic (1.76e-1)" "unprognostic (3.14e-1)" "unprognostic (1.17e-1)" "unprognostic (3.41e-1)" "unprognostic (2.25e-1)" "unprognostic (2.11e-2)" "unprognostic (3.33e-2)" "unprognostic (1.47e-1)" "unprognostic (1.30e-1)" "unprognostic (9.05e-2)" "unprognostic (1.42e-1)" IGLJ1 ENSG00000211674 "Immunoglobulin lambda joining 1" A0A0A0MT76 22 22893692-22893818 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "intestine: 94.1;lymphoid tissue: 50.0;salivary gland: 32.3;stomach 1: 38.0" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 95.5" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 25 "memory B-cell: 20.1;naive B-cell: 11.1" "Lineage enriched" "Detected in single" 32 "B-cells: 20.1" "Cancer enriched" "Detected in some" 5 "Myeloma: 966.9" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "unprognostic (7.26e-2)" "unprognostic (6.29e-2)" "unprognostic (2.35e-1)" "unprognostic (3.90e-2)" "potential prognostic favorable (9.46e-4)" "unprognostic (4.88e-2)" "unprognostic (1.92e-2)" "unprognostic (2.90e-1)" "unprognostic (4.29e-1)" "unprognostic (4.73e-2)" "unprognostic (5.26e-2)" "unprognostic (2.18e-1)" "unprognostic (6.67e-2)" "unprognostic (4.75e-1)" "unprognostic (3.38e-2)" "unprognostic (1.85e-1)" "unprognostic (1.78e-3)" "unprognostic (1.16e-2)" "unprognostic (3.20e-1)" "unprognostic (1.90e-1)" "unprognostic (1.51e-1)" IGLJ2 ENSG00000211676 "Immunoglobulin lambda joining 2" 22 22899481-22899655 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 246.0;lymphoid tissue: 177.7;stomach 1: 200.4" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Lung Squamous Cell Carcinoma (TCGA): 331.3" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 12 "memory B-cell: 882.3;naive B-cell: 871.4" "Lineage enriched" "Detected in many" 12 "B-cells: 882.3" "Group enriched" "Detected in some" 10 "lymphoma: 106.5;Myeloma: 122.9" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "unprognostic (3.09e-1)" "potential prognostic favorable (5.28e-4)" "unprognostic (2.20e-2)" "unprognostic (7.28e-2)" "unprognostic (2.49e-1)" "potential prognostic unfavorable (8.27e-4)" "potential prognostic favorable (1.54e-5)" "unprognostic (5.87e-3)" "unprognostic (5.39e-2)" "unprognostic (1.51e-1)" "unprognostic (3.10e-1)" "unprognostic (3.26e-2)" "unprognostic (4.06e-2)" "unprognostic (1.93e-1)" "unprognostic (2.27e-1)" "unprognostic (1.05e-2)" "unprognostic (3.26e-1)" "unprognostic (6.74e-2)" "unprognostic (1.58e-2)" "unprognostic (2.69e-1)" "unprognostic (8.12e-2)" "unprognostic (1.59e-1)" "unprognostic (5.51e-1)" "unprognostic (1.05e-1)" "unprognostic (2.83e-2)" IGLJ3 ENSG00000211678 "Immunoglobulin lambda joining 3" 22 22904850-22905025 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 7 "intestine: 519.9;lymphoid tissue: 213.5;salivary gland: 140.5;stomach 1: 435.4;urinary bladder: 138.3" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Lung Squamous Cell Carcinoma (TCGA): 488.0" "Region enhanced" "Detected in some" "cerebral cortex: 3.1" "Group enriched" "Detected in many" 24 "memory B-cell: 1232.2;naive B-cell: 1150.4" "Lineage enriched" "Detected in many" 25 "B-cells: 1232.2" "Cancer enriched" "Detected in some" 7 "Myeloma: 549.2" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 87: B-cells - Adaptive immunity: Humoral response" "unprognostic (3.59e-1)" "potential prognostic favorable (7.82e-5)" "unprognostic (1.77e-2)" "unprognostic (9.57e-2)" "unprognostic (2.63e-1)" "unprognostic (6.61e-3)" "potential prognostic favorable (8.60e-4)" "unprognostic (3.80e-1)" "unprognostic (2.62e-2)" "unprognostic (7.73e-2)" "unprognostic (1.77e-2)" "unprognostic (6.22e-2)" "unprognostic (1.25e-1)" "unprognostic (7.25e-2)" "unprognostic (6.09e-2)" "unprognostic (7.93e-3)" "unprognostic (9.66e-2)" "unprognostic (2.14e-1)" "unprognostic (1.16e-1)" "unprognostic (3.38e-2)" "unprognostic (5.63e-2)" "unprognostic (3.32e-2)" "unprognostic (4.15e-2)" "unprognostic (3.43e-1)" "unprognostic (2.15e-1)" "unprognostic (8.39e-2)" IGLJ4 ENSG00000211680 "Immunoglobulin lambda joining 4 (non-functional)" 22 22910574-22910606 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 30 "intestine: 1.8;lymphoid tissue: 4.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lymphoma: 6.3;Myeloma: 3.7" NA NA "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 54: Immune cells - T cell receptor" "Cluster 46: Lymphoma - Humoral immune response" IGLJ5 ENSG00000211681 "Immunoglobulin lambda joining 5 (non-functional)" 22 22914237-22914308 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "breast: 1.5;lymphoid tissue: 3.5;stomach 1: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 118 "memory B-cell: 15.3;naive B-cell: 14.3;plasmacytoid DC: 5.8" "Group enriched" "Detected in many" 106 "B-cells: 15.3;dendritic cells: 5.8" "Group enriched" "Detected in some" 9 "Leukemia: 1.7;lymphoma: 5.6;Myeloma: 2.2" "Minor Salivary Gland - Plasma cells" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 46: Lymphoma - Humoral immune response" IGLJ6 ENSG00000211682 "Immunoglobulin lambda joining 6" 22 22918132-22918201 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 6 "intestine: 6.3;lymphoid tissue: 7.5;urinary bladder: 4.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 47 "memory B-cell: 31.7;naive B-cell: 38.4" "Lineage enriched" "Detected in single" 52 "B-cells: 38.4" "Group enriched" "Detected in some" 8 "Leukemia: 4.0;lymphoma: 12.4" "Breast - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 46: Lymphoma - Humoral immune response" "unprognostic (1.64e-1)" "unprognostic (2.54e-1)" IGLJ7 ENSG00000211684 "Immunoglobulin lambda joining 7" 22 22921390-22921435 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "intestine: 11.5;lymphoid tissue: 17.5;stomach 1: 14.5" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 11.4;Stomach Adenocarcinoma (TCGA): 13.0" "Region enhanced" "Detected in many" "cerebral cortex: 6.5" "Group enriched" "Detected in some" 222 "memory B-cell: 314.3;naive B-cell: 372.7" "Lineage enriched" "Detected in many" 240 "B-cells: 372.7" "Group enriched" "Detected in some" 64 "Leukemia: 10.2;lymphoma: 40.8" "Breast - Plasma cells, Minor Salivary Gland - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 46: Lymphoma - Humoral immune response" "unprognostic (6.50e-2)" "unprognostic (7.63e-1)" "potential prognostic favorable (1.75e-4)" "unprognostic (4.41e-1)" "unprognostic (9.86e-2)" "unprognostic (5.32e-1)" "unprognostic (2.09e-1)" "unprognostic (2.86e-1)" "unprognostic (3.59e-1)" "unprognostic (3.14e-1)" "unprognostic (4.60e-1)" "unprognostic (3.41e-1)" "unprognostic (3.88e-1)" IGLL1 "14.1, CD179B, IGL5, IGLL, IGVPB" ENSG00000128322 "Immunoglobulin lambda like polypeptide 1" P15814 22 23573125-23580302 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 66.3;testis: 24.2" "Cell type enhanced" "Detected in some" "Early spermatids: 98.1;Late primary spermatocytes: 57.6;Late spermatids: 274.4;Neutrophil progenitors: 18.7;Thymocytes: 116.0" "Cell type enhanced" "Detected in single" "choroid plexus epithelial cell: 3.1" "Cancer enhanced" "Detected in single" "Stomach Adenocarcinoma (TCGA): 3.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "memory B-cell: 12.0;naive B-cell: 14.9" "Lineage enriched" "Detected in many" 11 "B-cells: 14.9" "Group enriched" "Detected in some" 13 "Leukemia: 379.0;lymphoma: 146.4" "Breast - Plasma cells, Minor Salivary Gland - Plasma cells, Stomach - Plasma cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "HPA051134, HPA071406" Enhanced Approved "Endoplasmic reticulum" "Secreted to blood" "No annotated function" NA NA 1200000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 35: RS4;11 - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 3 "Endoplasmic reticulum" "HPA051134: , HPA071406: " "unprognostic (1.95e-2)" IGLL5 ENSG00000254709 "Immunoglobulin lambda like polypeptide 5" B9A064 22 22887780-22896111 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 384.8;lymphoid tissue: 632.7;salivary gland: 263.6;stomach 1: 290.6" "Cell type enriched" "Detected in some" 100 "Plasma cells: 4048.5" "Cell type enriched" "Detected in single" 164 "leukocyte: 34.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 227 "memory B-cell: 517.6;naive B-cell: 619.6" "Lineage enriched" "Detected in many" 247 "B-cells: 619.6" "Cancer enriched" "Detected in some" 4 "Myeloma: 1179.4" "Secreted to blood" "No annotated function" NA NA 22000000000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 67: Plasma cells - Plasma cell differentiation" 36 "unprognostic (1.09e-2)" "unprognostic (1.76e-3)" "unprognostic (3.48e-2)" "unprognostic (1.87e-1)" "unprognostic (1.78e-1)" "unprognostic (1.74e-3)" "unprognostic (1.62e-1)" "potential prognostic favorable (5.40e-5)" "unprognostic (1.07e-1)" "unprognostic (1.19e-3)" "unprognostic (6.57e-2)" "unprognostic (4.75e-3)" "unprognostic (4.06e-2)" "unprognostic (1.06e-2)" "unprognostic (1.17e-1)" "unprognostic (5.79e-3)" "unprognostic (1.80e-1)" "unprognostic (4.54e-2)" "unprognostic (4.70e-2)" "unprognostic (9.33e-2)" "unprognostic (1.84e-1)" "unprognostic (3.75e-3)" "unprognostic (4.67e-1)" "unprognostic (1.76e-2)" "unprognostic (2.95e-1)" "unprognostic (7.78e-2)" "unprognostic (1.10e-1)" "unprognostic (4.12e-1)" "unprognostic (1.17e-1)" "unprognostic (1.70e-1)" IGLON5 LOC402665 ENSG00000142549 "IgLON family member 5" A6NGN9 19 51311644-51330891 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 48.8" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 17.7;Brain inhibitory neurons: 17.3;Esophageal apical cells: 14.0;Oligodendrocyte progenitor cells: 11.9;Other brain neurons: 20.6;Retinal amacrine cells: 55.4;Retinal bipolar cells: 14.7;Retinal horizontal cells: 90.2;Thymocytes: 11.9;Undifferentiated spermatogonia: 18.7" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 15.6;Testicular Germ Cell Tumor (TCGA): 21.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "Neuroblastoma: 15.2;testis cancer: 7.2" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Kidney - Macrophages, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041994 Approved "Secreted in brain" "No annotated function" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 49: Hindbrain - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" "HPA041994: " "unprognostic (3.75e-1)" "unprognostic (1.67e-1)" "unprognostic (1.04e-2)" "unprognostic (2.16e-3)" "unprognostic (2.25e-1)" "unprognostic (2.19e-2)" "unprognostic (1.55e-2)" "unprognostic (9.36e-2)" "unprognostic (1.38e-1)" "unprognostic (5.81e-2)" IGLV1-36 ENSG00000211655 "Immunoglobulin lambda variable 1-36" A0A0B4J1U3 22 22431958-22432465 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 250.5;stomach 1: 114.9;urinary bladder: 81.2" "Cell type enhanced" "Detected in some" "Foveolar cells: 1.2;Gastric chief cells: 1.1;Parietal cells: 1.8" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 41.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 625 "memory B-cell: 61.2;naive B-cell: 86.2" "Lineage enriched" "Detected in single" 731 "B-cells: 86.2" "Cancer enriched" "Detected in some" 45 "lymphoma: 117.2" "Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 34: B-cells - Unknown function" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 67: Plasma cells - Plasma cell differentiation" "unprognostic (2.65e-1)" "potential prognostic favorable (6.18e-5)" "unprognostic (3.74e-2)" "unprognostic (3.58e-1)" "unprognostic (1.87e-1)" "potential prognostic favorable (6.22e-4)" "unprognostic (1.26e-2)" "unprognostic (4.56e-1)" "potential prognostic unfavorable (4.34e-4)" "unprognostic (5.02e-2)" "unprognostic (2.14e-3)" "unprognostic (4.77e-2)" "unprognostic (1.52e-1)" "unprognostic (1.69e-1)" "unprognostic (2.48e-1)" "unprognostic (1.99e-1)" "unprognostic (3.23e-2)" "unprognostic (3.15e-2)" "unprognostic (1.90e-1)" "unprognostic (8.05e-2)" "unprognostic (1.78e-1)" "unprognostic (4.80e-2)" "unprognostic (3.31e-2)" "unprognostic (7.33e-2)" "unprognostic (1.18e-1)" "unprognostic (2.78e-1)" IGLV1-40 ENSG00000211653 "Immunoglobulin lambda variable 1-40" P01703 22 22409766-22410282 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1205.9;stomach 1: 1210.3" "Cell type enhanced" "Detected in some" "Foveolar cells: 1.3;Gastric chief cells: 5.5;Mucous neck cells: 1.6;Parietal cells: 1.8;Plasma cells: 7.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 493 "memory B-cell: 669.2;naive B-cell: 580.6" "Lineage enriched" "Detected in many" 528 "B-cells: 669.2" "Cancer enriched" "Detected in some" 14 "Myeloma: 2249.4" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 67: Plasma cells - Plasma cell differentiation" "unprognostic (1.54e-2)" "potential prognostic favorable (6.30e-4)" "unprognostic (4.53e-2)" "unprognostic (1.79e-1)" "unprognostic (1.11e-1)" "potential prognostic unfavorable (7.14e-4)" "unprognostic (4.18e-2)" "potential prognostic favorable (4.27e-5)" "unprognostic (4.25e-1)" "unprognostic (4.12e-3)" "unprognostic (2.72e-2)" "unprognostic (1.59e-3)" "unprognostic (1.36e-2)" "unprognostic (2.97e-2)" "unprognostic (2.46e-2)" "unprognostic (1.33e-2)" "unprognostic (1.31e-2)" "unprognostic (6.86e-2)" "unprognostic (1.54e-1)" "unprognostic (1.28e-1)" "unprognostic (3.16e-3)" "unprognostic (2.00e-1)" "unprognostic (2.08e-2)" "unprognostic (4.52e-2)" "unprognostic (1.28e-1)" "unprognostic (1.25e-1)" "unprognostic (1.48e-1)" "unprognostic (1.56e-1)" "unprognostic (2.80e-1)" IGLV1-44 ENSG00000211651 "Immunoglobulin lambda variable 1-44" P01699 22 22380766-22381347 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 563.1;lymphoid tissue: 1800.5;stomach 1: 493.6" "Cell type enhanced" "Detected in some" "Foveolar cells: 5.3;Gastric chief cells: 13.1;Mucous neck cells: 1.9;Neuroendocrine cells: 1.4;Parietal cells: 3.5;Plasma cells: 23.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Lung Squamous Cell Carcinoma (TCGA): 311.0" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 839 "memory B-cell: 975.4;naive B-cell: 853.6" "Lineage enriched" "Detected in many" 895 "B-cells: 975.4" "Group enriched" "Detected in some" 164 "lymphoma: 40.0;Myeloma: 93.6" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 78: Plasma cells - Antibody production & ER-stress response" "unprognostic (3.63e-1)" "potential prognostic favorable (8.54e-4)" "unprognostic (4.12e-2)" "unprognostic (2.45e-2)" "unprognostic (1.10e-1)" "unprognostic (1.69e-1)" "unprognostic (3.71e-2)" "potential prognostic favorable (7.57e-5)" "potential prognostic unfavorable (8.72e-4)" "unprognostic (8.29e-2)" "unprognostic (1.75e-2)" "unprognostic (3.57e-2)" "unprognostic (1.84e-1)" "unprognostic (2.98e-2)" "unprognostic (1.35e-1)" "unprognostic (3.67e-2)" "unprognostic (1.44e-1)" "unprognostic (2.61e-1)" "unprognostic (9.94e-2)" "unprognostic (3.28e-2)" "unprognostic (1.29e-1)" "unprognostic (6.53e-2)" "unprognostic (2.85e-1)" "unprognostic (1.37e-1)" "unprognostic (7.94e-2)" "unprognostic (5.52e-2)" "unprognostic (1.16e-1)" "unprognostic (2.71e-1)" IGLV1-47 ENSG00000211648 "Immunoglobulin lambda variable 1-47" P01700 22 22357739-22358260 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 662.3;lymphoid tissue: 1683.7;stomach 1: 588.0" "Cell type enriched" "Detected in some" 9 "Plasma cells: 88.9" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 639 "memory B-cell: 1525.2;naive B-cell: 824.7" "Lineage enriched" "Detected in many" 830 "B-cells: 1525.2" "Cancer enriched" "Detected in some" 235 "Myeloma: 3497.7" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 44: Plasma cells - Antibody production & secretion" "unprognostic (1.85e-2)" "unprognostic (1.86e-3)" "unprognostic (1.20e-1)" "unprognostic (1.44e-1)" "unprognostic (2.05e-1)" "unprognostic (2.49e-2)" "unprognostic (2.90e-1)" "potential prognostic favorable (3.49e-4)" "unprognostic (3.31e-1)" "unprognostic (6.12e-3)" "unprognostic (8.88e-2)" "unprognostic (5.87e-3)" "unprognostic (2.79e-2)" "unprognostic (1.13e-1)" "unprognostic (6.98e-2)" "unprognostic (6.25e-2)" "unprognostic (2.76e-1)" "unprognostic (4.90e-2)" "unprognostic (4.44e-2)" "unprognostic (2.23e-1)" "unprognostic (1.39e-3)" "unprognostic (4.17e-1)" "unprognostic (2.99e-2)" "unprognostic (1.42e-1)" "unprognostic (1.23e-1)" "unprognostic (2.53e-3)" "unprognostic (1.88e-1)" "unprognostic (1.02e-1)" "unprognostic (2.13e-1)" IGLV1-50 ENSG00000211645 "Immunoglobulin lambda variable 1-50 (non-functional)" A0A075B6I6 22 22327300-22327814 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 15.4;lymphoid tissue: 13.7;stomach 1: 19.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 21 "memory B-cell: 11.0;naive B-cell: 2.9" "Lineage enriched" "Detected in single" 33 "B-cells: 11.0" "Group enriched" "Detected in some" 7 "lymphoma: 2.1;Myeloma: 4.3" "Breast - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 37: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "unprognostic (6.52e-1)" "potential prognostic favorable (7.37e-4)" "unprognostic (7.87e-2)" "unprognostic (4.97e-2)" "unprognostic (1.10e-1)" "unprognostic (1.78e-2)" "potential prognostic favorable (2.04e-4)" "unprognostic (2.08e-2)" "unprognostic (1.11e-1)" "potential prognostic unfavorable (2.55e-5)" "unprognostic (1.59e-1)" "unprognostic (8.88e-2)" "unprognostic (4.08e-2)" "unprognostic (3.70e-1)" "unprognostic (2.09e-2)" "unprognostic (2.54e-1)" "unprognostic (7.91e-3)" "unprognostic (8.19e-2)" "unprognostic (1.41e-2)" "unprognostic (1.15e-1)" "unprognostic (1.24e-1)" "unprognostic (1.48e-1)" IGLV1-51 ENSG00000211644 "Immunoglobulin lambda variable 1-51" P01701 22 22322472-22322969 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 1231.3;lymphoid tissue: 2823.5;urinary bladder: 1487.4" "Group enriched" "Detected in some" 14 "Gastric chief cells: 2.2;Plasma cells: 7.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "memory B-cell: 277.1;naive B-cell: 179.3" "Lineage enriched" "Detected in many" 11 "B-cells: 277.1" "Group enriched" "Detected in many" 52 "lymphoma: 181.2;Myeloma: 189.3" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 37: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 78: Plasma cells - Antibody production & ER-stress response" "unprognostic (1.95e-1)" "potential prognostic favorable (3.19e-4)" "unprognostic (3.60e-2)" "unprognostic (9.59e-2)" "unprognostic (3.30e-2)" "unprognostic (1.02e-2)" "unprognostic (3.34e-3)" "potential prognostic favorable (1.48e-4)" "unprognostic (2.62e-1)" "unprognostic (4.85e-2)" "unprognostic (7.82e-2)" "unprognostic (1.83e-2)" "unprognostic (3.17e-2)" "unprognostic (1.27e-3)" "unprognostic (1.41e-2)" "unprognostic (2.09e-1)" "unprognostic (4.88e-2)" "unprognostic (1.94e-2)" "unprognostic (2.60e-1)" "unprognostic (6.17e-2)" "unprognostic (5.79e-2)" "unprognostic (3.97e-1)" "unprognostic (4.99e-2)" "unprognostic (3.29e-1)" "unprognostic (8.23e-2)" "unprognostic (6.88e-2)" "unprognostic (8.10e-2)" "unprognostic (1.45e-1)" "unprognostic (9.60e-2)" IGLV10-54 ENSG00000211642 "Immunoglobulin lambda variable 10-54" A0A075B6I4 22 22214794-22215270 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 7 "breast: 113.1;intestine: 303.0;lymphoid tissue: 306.7;salivary gland: 238.7;stomach 1: 182.8" "Cell type enriched" "Detected in some" 6 "Plasma cells: 13.8" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 4 "cerebral cortex: 2.0;choroid plexus: 1.4;medulla oblongata: 2.6;white matter: 1.0" "Group enriched" "Detected in some" 32 "memory B-cell: 59.2;naive B-cell: 35.1" "Lineage enriched" "Detected in many" 40 "B-cells: 59.2" "Not detected" "Not detected" "Adipose visceral - Plasma cells, Breast - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Spleen - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 34: B-cells - Unknown function" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 44: Plasma cells - Antibody production & secretion" "unprognostic (2.01e-1)" "potential prognostic favorable (1.66e-4)" "unprognostic (1.76e-2)" "unprognostic (4.70e-3)" "unprognostic (7.55e-2)" "potential prognostic favorable (4.49e-5)" "unprognostic (2.82e-2)" "unprognostic (7.02e-2)" "potential prognostic unfavorable (3.83e-4)" "unprognostic (1.46e-1)" "unprognostic (1.10e-1)" "unprognostic (2.45e-1)" "unprognostic (1.05e-1)" "unprognostic (8.94e-2)" "unprognostic (1.03e-1)" "unprognostic (3.40e-1)" "unprognostic (7.51e-2)" "unprognostic (1.13e-2)" "unprognostic (7.39e-2)" "unprognostic (2.83e-2)" "unprognostic (4.01e-2)" "unprognostic (2.72e-1)" "unprognostic (1.34e-1)" "unprognostic (1.95e-1)" "unprognostic (1.07e-2)" "unprognostic (2.96e-1)" IGLV11-55 ENSG00000211641 "Immunoglobulin lambda variable 11-55 (non-functional)" A0A075B6I3 22 22201663-22202161 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.0" "Cell type enriched" "Detected in single" 8 "Late spermatids: 7.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lymphoma: 1.9" "Breast - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" "unprognostic (6.05e-2)" IGLV2-11 ENSG00000211668 "Immunoglobulin lambda variable 2-11" P01706 22 22792491-22793007 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1449.0;lymphoid tissue: 2730.6" "Group enriched" "Detected in some" 6 "Gastric chief cells: 13.1;Plasma cells: 50.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 37 "memory B-cell: 1408.5;naive B-cell: 855.5" "Lineage enriched" "Detected in many" 46 "B-cells: 1408.5" "Cancer enriched" "Detected in some" 12 "Myeloma: 2659.7" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 78: Plasma cells - Antibody production & ER-stress response" "unprognostic (5.58e-2)" "unprognostic (4.50e-3)" "unprognostic (5.87e-2)" "unprognostic (2.71e-2)" "unprognostic (2.06e-1)" "potential prognostic unfavorable (6.99e-4)" "unprognostic (2.66e-1)" "potential prognostic favorable (8.44e-5)" "unprognostic (3.47e-1)" "unprognostic (2.43e-2)" "unprognostic (5.54e-2)" "unprognostic (3.37e-3)" "unprognostic (5.07e-3)" "unprognostic (6.97e-2)" "unprognostic (5.46e-2)" "unprognostic (1.21e-1)" "unprognostic (1.13e-1)" "unprognostic (3.53e-2)" "unprognostic (4.48e-1)" "unprognostic (2.68e-1)" "unprognostic (3.16e-3)" "unprognostic (3.30e-1)" "unprognostic (5.48e-2)" "unprognostic (6.48e-2)" "unprognostic (7.05e-2)" "unprognostic (4.98e-2)" "unprognostic (1.33e-1)" "unprognostic (3.23e-1)" "unprognostic (1.20e-1)" IGLV2-14 ENSG00000211666 "Immunoglobulin lambda variable 2-14" P01704 22 22758700-22759218 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 2450.3;lymphoid tissue: 5019.4;stomach 1: 2378.3" "Cell type enriched" "Detected in some" 6 "Plasma cells: 179.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 51 "memory B-cell: 3671.8;naive B-cell: 2675.2" "Lineage enriched" "Detected in all" 59 "B-cells: 3671.8" "Cancer enriched" "Detected in many" 10 "Myeloma: 6526.2" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 78: Plasma cells - Antibody production & ER-stress response" "unprognostic (1.45e-2)" "unprognostic (1.18e-3)" "unprognostic (1.56e-3)" "unprognostic (9.59e-2)" "unprognostic (3.79e-2)" "unprognostic (1.21e-2)" "unprognostic (1.65e-1)" "potential prognostic favorable (4.87e-4)" "unprognostic (5.08e-1)" "unprognostic (3.42e-2)" "unprognostic (9.72e-2)" "unprognostic (1.55e-3)" "unprognostic (3.49e-1)" "unprognostic (1.95e-1)" "unprognostic (3.39e-2)" "unprognostic (1.78e-1)" "unprognostic (1.73e-2)" "unprognostic (1.35e-2)" "unprognostic (1.52e-1)" "unprognostic (1.02e-1)" "potential prognostic favorable (4.72e-4)" "unprognostic (3.04e-1)" "unprognostic (5.22e-2)" "unprognostic (1.93e-1)" "unprognostic (6.26e-2)" "unprognostic (2.16e-1)" "unprognostic (8.97e-2)" "unprognostic (1.34e-1)" "unprognostic (2.05e-1)" IGLV2-18 ENSG00000211664 "Immunoglobulin lambda variable 2-18" A0A075B6J9 22 22734607-22735089 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 253.4;lymphoid tissue: 209.0" "Cell type enriched" "Detected in some" 4 "Plasma cells: 7.4" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 44 "memory B-cell: 322.8;naive B-cell: 127.9" "Lineage enriched" "Detected in many" 64 "B-cells: 322.8" "Cancer enriched" "Detected in some" 1869 "Myeloma: 5114.0" "Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 78: Plasma cells - Antibody production & ER-stress response" "unprognostic (1.86e-1)" "potential prognostic favorable (1.10e-4)" "unprognostic (1.33e-2)" "unprognostic (1.64e-1)" "unprognostic (4.47e-2)" "unprognostic (2.11e-3)" "unprognostic (1.99e-1)" "unprognostic (2.65e-2)" "unprognostic (1.49e-1)" "unprognostic (2.80e-3)" "unprognostic (8.75e-3)" "unprognostic (3.82e-2)" "unprognostic (2.51e-2)" "unprognostic (1.72e-1)" "unprognostic (1.76e-1)" "unprognostic (7.34e-2)" "unprognostic (1.07e-1)" "unprognostic (4.36e-2)" "unprognostic (2.10e-3)" "unprognostic (6.70e-2)" "unprognostic (3.62e-2)" "unprognostic (2.54e-1)" "unprognostic (1.20e-1)" "unprognostic (1.93e-1)" "unprognostic (1.03e-1)" "unprognostic (1.76e-1)" "unprognostic (1.02e-1)" IGLV2-23 ENSG00000211660 "Immunoglobulin lambda variable 2-23" P01705 22 22697789-22698407 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 649.4;lymphoid tissue: 1494.9;stomach 1: 632.1" "Cell type enriched" "Detected in some" 7 "Plasma cells: 62.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 368 "memory B-cell: 2082.0;naive B-cell: 2618.1" "Lineage enriched" "Detected in all" 410 "B-cells: 2618.1" "Cancer enriched" "Detected in some" 24 "Myeloma: 4664.0" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 67: Plasma cells - Plasma cell differentiation" "unprognostic (3.11e-1)" "potential prognostic favorable (1.36e-4)" "unprognostic (9.40e-2)" "unprognostic (2.78e-1)" "unprognostic (7.17e-2)" "unprognostic (5.03e-3)" "unprognostic (7.34e-2)" "unprognostic (7.93e-3)" "unprognostic (2.15e-1)" "unprognostic (2.37e-2)" "unprognostic (2.51e-1)" "potential prognostic unfavorable (4.71e-5)" "unprognostic (7.10e-3)" "unprognostic (1.17e-2)" "unprognostic (8.90e-2)" "unprognostic (9.85e-2)" "unprognostic (6.51e-2)" "unprognostic (4.40e-2)" "unprognostic (4.26e-1)" "unprognostic (9.91e-2)" "potential prognostic favorable (5.76e-5)" "unprognostic (1.87e-2)" "unprognostic (3.08e-2)" "unprognostic (1.80e-1)" "unprognostic (8.61e-2)" "unprognostic (1.60e-1)" "unprognostic (9.61e-2)" "unprognostic (1.62e-1)" "unprognostic (1.72e-1)" IGLV2-33 ENSG00000211656 "Immunoglobulin lambda variable 2-33 (non-functional)" A0A075B6J2 22 22588155-22588688 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 4.0;lymphoid tissue: 2.6;salivary gland: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Lung Adenocarcinoma (TCGA): 2.4;Lung Squamous Cell Carcinoma (TCGA): 2.2" "Not detected" "Not detected" "Group enriched" "Detected in some" 25 "memory B-cell: 3.0;naive B-cell: 1.9" "Lineage enriched" "Detected in single" 30 "B-cells: 3.0" "Not detected" "Not detected" "Breast - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 20: Myeloma - Immune response" "unprognostic (2.69e-1)" "unprognostic (2.15e-1)" "unprognostic (7.69e-2)" "unprognostic (6.85e-2)" "unprognostic (3.43e-1)" "unprognostic (1.15e-1)" IGLV2-8 ENSG00000278196 "Immunoglobulin lambda variable 2-8" P01709 22 22822658-22823289 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1068.4;lymphoid tissue: 946.6" "Cell type enriched" "Detected in some" 6 "Plasma cells: 88.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 125 "memory B-cell: 1445.0;naive B-cell: 2116.3" "Lineage enriched" "Detected in all" 149 "B-cells: 2116.3" "Cancer enriched" "Detected in many" 82 "Myeloma: 4571.8" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 20: Myeloma - Immune response" "Cluster 78: Plasma cells - Antibody production & ER-stress response" "unprognostic (6.71e-2)" "potential prognostic favorable (3.42e-4)" "unprognostic (3.19e-2)" "unprognostic (1.80e-1)" "unprognostic (1.55e-1)" "unprognostic (6.52e-2)" "potential prognostic favorable (5.79e-5)" "unprognostic (1.13e-1)" "unprognostic (4.95e-2)" "unprognostic (3.08e-1)" "unprognostic (4.90e-3)" "unprognostic (1.43e-2)" "unprognostic (9.04e-2)" "unprognostic (5.53e-3)" "unprognostic (1.13e-1)" "unprognostic (7.75e-2)" "unprognostic (5.24e-2)" "unprognostic (1.91e-1)" "unprognostic (1.96e-1)" "unprognostic (2.35e-1)" "unprognostic (2.32e-1)" "unprognostic (8.30e-2)" "unprognostic (6.14e-2)" "unprognostic (3.15e-1)" "unprognostic (1.00e-1)" "unprognostic (2.86e-1)" IGLV3-1 ENSG00000211673 "Immunoglobulin lambda variable 3-1" P01715 22 22880706-22881396 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1153.2;lymphoid tissue: 3105.1;stomach 1: 1371.6" "Cell type enriched" "Detected in some" 24 "Plasma cells: 301.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 728 "memory B-cell: 783.5;naive B-cell: 1045.8" "Lineage enriched" "Detected in many" 833 "B-cells: 1045.8" "Cancer enriched" "Detected in some" 4 "lymphoma: 146.5" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" HPA003285 Approved "Immunoglobulin genes" Immunity NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 44: Plasma cells - Antibody production & secretion" "HPA003285: " "unprognostic (9.31e-3)" "potential prognostic favorable (2.68e-4)" "unprognostic (1.52e-1)" "unprognostic (7.50e-2)" "unprognostic (2.59e-1)" "unprognostic (1.17e-2)" "unprognostic (5.02e-1)" "potential prognostic favorable (5.40e-4)" "unprognostic (4.45e-2)" "unprognostic (2.19e-3)" "unprognostic (2.69e-1)" "unprognostic (1.92e-3)" "unprognostic (3.83e-2)" "unprognostic (6.28e-2)" "unprognostic (2.25e-2)" "unprognostic (4.27e-1)" "unprognostic (4.83e-2)" "unprognostic (3.22e-2)" "unprognostic (3.86e-1)" "unprognostic (2.85e-1)" "unprognostic (2.70e-3)" "unprognostic (1.15e-1)" "unprognostic (7.63e-3)" "unprognostic (3.94e-2)" "unprognostic (1.47e-1)" "unprognostic (4.62e-2)" "unprognostic (4.43e-1)" "unprognostic (1.45e-1)" "unprognostic (3.59e-1)" IGLV3-10 ENSG00000211669 "Immunoglobulin lambda variable 3-10" A0A075B6K4 22 22811747-22812281 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 296.3;lymphoid tissue: 659.0;stomach 1: 271.5" "Group enriched" "Detected in some" 9 "Gastric chief cells: 6.6;Plasma cells: 18.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "medulla oblongata: 3.4" "Group enriched" "Detected in some" 785 "memory B-cell: 550.8;naive B-cell: 316.8" "Lineage enriched" "Detected in single" 997 "B-cells: 550.8" "Cancer enriched" "Detected in some" 67 "Myeloma: 3522.7" "Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" HPA003285 Approved "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 44: Plasma cells - Antibody production & secretion" "HPA003285: " "unprognostic (2.28e-2)" "unprognostic (4.68e-2)" "unprognostic (5.86e-3)" "unprognostic (9.25e-2)" "unprognostic (1.02e-1)" "unprognostic (2.06e-2)" "potential prognostic favorable (4.80e-4)" "unprognostic (3.17e-1)" "potential prognostic unfavorable (4.90e-4)" "unprognostic (3.55e-2)" "unprognostic (1.18e-2)" "unprognostic (5.34e-3)" "unprognostic (1.56e-2)" "unprognostic (3.92e-3)" "unprognostic (2.80e-1)" "unprognostic (9.22e-2)" "unprognostic (1.72e-1)" "unprognostic (3.67e-2)" "unprognostic (3.11e-1)" "unprognostic (2.25e-3)" "unprognostic (2.10e-1)" "unprognostic (9.16e-3)" "unprognostic (1.41e-1)" "unprognostic (2.09e-1)" "unprognostic (1.12e-1)" "unprognostic (1.88e-1)" "unprognostic (2.36e-1)" "unprognostic (2.61e-1)" IGLV3-12 ENSG00000211667 "Immunoglobulin lambda variable 3-12" A0A075B6K2 22 22771824-22772582 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 28.1;stomach 1: 7.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "gdT-cell: 4.3;memory B-cell: 9.2;memory CD8 T-cell: 4.0;naive B-cell: 6.8;NK-cell: 5.7" "Group enriched" "Detected in many" 64 "B-cells: 9.2;NK-cells: 5.7;T-cells: 4.3" "Not detected" "Not detected" "Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Stomach - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 44: Plasma cells - Antibody production & secretion" "unprognostic (2.79e-1)" "potential prognostic favorable (3.83e-4)" "unprognostic (4.25e-2)" "unprognostic (3.86e-1)" "unprognostic (6.74e-2)" "potential prognostic favorable (3.03e-4)" "unprognostic (2.43e-2)" "unprognostic (1.80e-1)" "unprognostic (3.27e-1)" "unprognostic (2.67e-1)" "unprognostic (5.62e-2)" "unprognostic (7.41e-2)" "unprognostic (8.62e-2)" "unprognostic (7.35e-2)" "unprognostic (8.01e-2)" "unprognostic (3.80e-1)" "unprognostic (4.38e-2)" "unprognostic (1.69e-1)" "unprognostic (3.43e-1)" "unprognostic (5.21e-1)" IGLV3-16 ENSG00000211665 "Immunoglobulin lambda variable 3-16" A0A075B6K0 22 22747383-22747921 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "lymphoid tissue: 75.0;urinary bladder: 40.1" "Cell type enhanced" "Detected in some" "Gastric chief cells: 1.1;Plasma cells: 1.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 394 "memory B-cell: 107.8;naive B-cell: 122.0" "Lineage enriched" "Detected in single" 418 "B-cells: 122.0" "Cancer enriched" "Detected in single" 398 "Myeloma: 61.3" "Adipose visceral - Plasma cells, Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Prostate - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 44: Plasma cells - Antibody production & secretion" "unprognostic (1.60e-1)" "potential prognostic favorable (1.91e-4)" "unprognostic (8.96e-3)" "unprognostic (1.59e-2)" "unprognostic (6.02e-2)" "potential prognostic favorable (3.94e-6)" "unprognostic (1.06e-1)" "unprognostic (2.92e-3)" "unprognostic (1.35e-2)" "unprognostic (8.88e-2)" "unprognostic (2.33e-3)" "unprognostic (2.16e-2)" "unprognostic (1.91e-2)" "unprognostic (1.29e-1)" "unprognostic (7.78e-2)" "unprognostic (1.99e-2)" "unprognostic (1.14e-1)" "unprognostic (1.04e-2)" "unprognostic (1.49e-1)" "unprognostic (5.05e-2)" "unprognostic (1.61e-1)" "unprognostic (3.50e-1)" "unprognostic (2.33e-2)" "unprognostic (2.78e-1)" IGLV3-19 ENSG00000211663 "Immunoglobulin lambda variable 3-19" P01714 22 22720623-22721145 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 958.6;lymphoid tissue: 1845.7;stomach 1: 1165.5" "Group enriched" "Detected in some" 4 "Gastric chief cells: 21.8;Parietal cells: 10.6;Plasma cells: 32.4" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 353 "memory B-cell: 621.3;naive B-cell: 506.4" "Lineage enriched" "Detected in many" 389 "B-cells: 621.3" "Cancer enriched" "Detected in single" 272 "lymphoma: 199.2" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 22: Non-specific - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 67: Plasma cells - Plasma cell differentiation" "unprognostic (3.86e-2)" "potential prognostic favorable (4.91e-4)" "unprognostic (5.45e-2)" "unprognostic (5.58e-2)" "unprognostic (3.38e-1)" "unprognostic (6.91e-2)" "unprognostic (2.49e-1)" "unprognostic (1.29e-3)" "unprognostic (2.07e-1)" "potential prognostic unfavorable (4.28e-4)" "unprognostic (1.53e-1)" "potential prognostic unfavorable (7.35e-4)" "unprognostic (4.41e-3)" "unprognostic (1.38e-1)" "unprognostic (9.79e-3)" "unprognostic (5.78e-2)" "unprognostic (4.41e-2)" "unprognostic (1.53e-1)" "unprognostic (2.66e-1)" "unprognostic (3.83e-1)" "potential prognostic favorable (1.28e-4)" "unprognostic (2.09e-1)" "unprognostic (1.55e-2)" "unprognostic (1.34e-1)" "unprognostic (1.81e-1)" "unprognostic (2.39e-1)" "unprognostic (2.49e-1)" "unprognostic (1.06e-1)" "unprognostic (2.12e-2)" IGLV3-21 ENSG00000211662 "Immunoglobulin lambda variable 3-21" P80748 22 22711689-22713203 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1697.1;urinary bladder: 725.7" "Cell type enriched" "Detected in some" 8 "Plasma cells: 83.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 337 "memory B-cell: 433.3;naive B-cell: 225.5" "Lineage enriched" "Detected in single" 444 "B-cells: 433.3" "Cancer enriched" "Detected in some" 15 "Myeloma: 691.2" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Testis - Early spermatids, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 44: Plasma cells - Antibody production & secretion" "unprognostic (2.06e-2)" "potential prognostic favorable (9.94e-4)" "unprognostic (5.34e-2)" "unprognostic (1.77e-1)" "unprognostic (5.83e-2)" "potential prognostic unfavorable (9.80e-5)" "unprognostic (2.25e-1)" "potential prognostic favorable (1.58e-6)" "unprognostic (1.06e-1)" "potential prognostic unfavorable (7.42e-6)" "unprognostic (2.78e-2)" "unprognostic (2.90e-3)" "unprognostic (2.01e-1)" "unprognostic (8.08e-3)" "unprognostic (8.52e-3)" "unprognostic (1.97e-1)" "unprognostic (1.82e-1)" "unprognostic (4.23e-2)" "unprognostic (7.62e-2)" "unprognostic (3.41e-1)" "unprognostic (6.28e-2)" "unprognostic (2.26e-1)" "unprognostic (1.52e-2)" "unprognostic (7.03e-2)" "unprognostic (2.76e-1)" "unprognostic (5.54e-2)" "unprognostic (1.46e-1)" "unprognostic (2.21e-1)" "unprognostic (1.07e-1)" IGLV3-22 ENSG00000211661 "Immunoglobulin lambda variable 3-22" A0A075B6J6 22 22704265-22704822 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 2.4;lymphoid tissue: 8.8" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Lung Squamous Cell Carcinoma (TCGA): 3.8;Ovary Serous Cystadenocarcinoma (TCGA): 3.8" "Not detected" "Not detected" "Group enriched" "Detected in some" 72 "memory B-cell: 6.6;naive B-cell: 7.8" "Lineage enriched" "Detected in single" 78 "B-cells: 7.8" "Cancer enriched" "Detected in single" 11 "Myeloma: 3.0" "Breast - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 44: Plasma cells - Antibody production & secretion" "unprognostic (1.19e-1)" "unprognostic (5.88e-3)" "unprognostic (3.12e-1)" "unprognostic (4.15e-2)" "unprognostic (2.85e-1)" "unprognostic (4.49e-2)" IGLV3-25 ENSG00000211659 "Immunoglobulin lambda variable 3-25" P01717 22 22686726-22687271 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 2274.5;stomach 1: 955.0" "Cell type enhanced" "Detected in some" "Foveolar cells: 2.3;Gastric chief cells: 12.0;Mucous neck cells: 2.4;Parietal cells: 5.3;Plasma cells: 24.0" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 45 "memory B-cell: 547.5;naive B-cell: 799.3" "Lineage enriched" "Detected in many" 53 "B-cells: 799.3" "Cancer enriched" "Detected in some" 14 "Myeloma: 1932.5" "Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" HPA003285 Approved "Immunoglobulin genes" Immunity NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 67: Plasma cells - Plasma cell differentiation" "HPA003285: " "unprognostic (1.71e-2)" "potential prognostic favorable (1.29e-4)" "unprognostic (2.08e-1)" "unprognostic (3.03e-2)" "unprognostic (1.24e-1)" "unprognostic (7.02e-3)" "unprognostic (3.10e-1)" "potential prognostic favorable (3.02e-4)" "unprognostic (5.36e-2)" "unprognostic (5.52e-3)" "unprognostic (2.21e-1)" "unprognostic (1.61e-3)" "unprognostic (4.04e-2)" "unprognostic (4.19e-2)" "unprognostic (1.24e-3)" "unprognostic (1.87e-2)" "unprognostic (3.22e-2)" "unprognostic (9.74e-3)" "unprognostic (1.51e-2)" "unprognostic (1.70e-1)" "unprognostic (3.55e-2)" "unprognostic (3.08e-1)" "unprognostic (1.18e-3)" "unprognostic (7.85e-2)" "unprognostic (1.21e-1)" "unprognostic (1.37e-1)" "unprognostic (1.25e-1)" "unprognostic (1.97e-1)" "unprognostic (1.67e-1)" IGLV3-27 ENSG00000211658 "Immunoglobulin lambda variable 3-27" P01718 22 22668288-22668806 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "lymphoid tissue: 374.9" "Cell type enriched" "Detected in single" 8 "Plasma cells: 5.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 95.3" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 720 "memory B-cell: 194.8;naive B-cell: 371.2" "Lineage enriched" "Detected in single" 945 "B-cells: 371.2" "Not detected" "Not detected" "Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 67: Plasma cells - Plasma cell differentiation" "unprognostic (7.36e-3)" "unprognostic (2.08e-2)" "unprognostic (1.50e-2)" "unprognostic (2.18e-1)" "unprognostic (9.10e-2)" "unprognostic (2.99e-1)" "potential prognostic favorable (7.69e-7)" "potential prognostic unfavorable (2.25e-4)" "unprognostic (6.01e-2)" "unprognostic (7.48e-3)" "unprognostic (7.07e-2)" "unprognostic (3.50e-2)" "unprognostic (1.01e-3)" "unprognostic (7.79e-2)" "unprognostic (5.74e-2)" "unprognostic (3.87e-1)" "unprognostic (2.61e-1)" "unprognostic (6.37e-2)" "unprognostic (2.43e-2)" "unprognostic (1.68e-1)" "unprognostic (6.82e-3)" "unprognostic (7.95e-3)" "unprognostic (1.33e-1)" "unprognostic (8.17e-2)" "unprognostic (2.21e-1)" "unprognostic (1.64e-1)" "unprognostic (2.11e-1)" IGLV3-32 ENSG00000211657 "Immunoglobulin lambda variable 3-32 (non-functional)" A0A0A0MS00 22 22594528-22595056 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "urinary bladder: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Lung Squamous Cell Carcinoma (TCGA): 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 34: Lymphoid tissue - Adaptive immune response" "unprognostic (1.48e-1)" "unprognostic (2.87e-1)" IGLV3-9 ENSG00000211670 "Immunoglobulin lambda variable 3-9" A0A075B6K5 22 22819010-22819756 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 292.8;stomach 1: 110.1" "Group enriched" "Detected in some" 4 "Plasma cells: 7.7;Platelets: 2.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 4 "medulla oblongata: 1.6" "Group enriched" "Detected in many" 52 "memory B-cell: 64.9;naive B-cell: 170.3" "Lineage enriched" "Detected in many" 75 "B-cells: 170.3" "Cancer enriched" "Detected in some" 4 "Myeloma: 5.0" "Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" HPA003285 Approved "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 18: Non-specific - Mixed function" "Cluster 20: Myeloma - Immune response" "Cluster 67: Plasma cells - Plasma cell differentiation" "HPA003285: " "unprognostic (2.05e-3)" "potential prognostic favorable (2.42e-5)" "potential prognostic favorable (9.58e-5)" "unprognostic (4.20e-1)" "unprognostic (1.03e-1)" "potential prognostic favorable (4.91e-5)" "unprognostic (2.51e-1)" "unprognostic (9.99e-3)" "unprognostic (7.55e-2)" "unprognostic (4.86e-2)" "unprognostic (3.53e-2)" "unprognostic (2.35e-1)" "unprognostic (6.05e-3)" "unprognostic (1.79e-1)" "unprognostic (1.90e-2)" "unprognostic (1.37e-1)" "unprognostic (2.59e-1)" "unprognostic (1.75e-2)" "unprognostic (3.97e-2)" "unprognostic (1.75e-1)" "unprognostic (4.56e-3)" "unprognostic (1.49e-1)" "unprognostic (1.33e-2)" "unprognostic (4.13e-3)" "unprognostic (5.78e-2)" "unprognostic (4.18e-2)" "unprognostic (3.40e-1)" IGLV4-3 ENSG00000211672 "Immunoglobulin lambda variable 4-3" A0A075B6K6 22 22871507-22872035 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 4 "lymphoid tissue: 14.7;stomach 1: 27.2" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Lung Squamous Cell Carcinoma (TCGA): 9.8" "Region enhanced" "Detected in single" "medulla oblongata: 1.1" "Group enriched" "Detected in some" 98 "memory B-cell: 11.8;naive B-cell: 7.8" "Lineage enriched" "Detected in single" 119 "B-cells: 11.8" "Group enriched" "Detected in some" 35 "Leukemia: 30.3;Myeloma: 79.8" "Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Not detected" "Not detected" "Immunoglobulin genes" Immunity NA NA "Cluster 34: B-cells - Unknown function" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 44: Plasma cells - Antibody production & secretion" "unprognostic (4.60e-2)" "unprognostic (4.03e-2)" "potential prognostic favorable (3.65e-4)" "unprognostic (2.81e-2)" "unprognostic (1.80e-1)" "unprognostic (3.32e-2)" "unprognostic (2.12e-2)" "unprognostic (1.40e-1)" "unprognostic (1.07e-1)" "unprognostic (1.07e-1)" IGLV4-60 ENSG00000211639 "Immunoglobulin lambda variable 4-60" A0A075B6I1 22 22162199-22162681 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 181.0;lymphoid tissue: 109.0;urinary bladder: 174.3" "Cell type enriched" "Detected in single" 14 "Plasma cells: 5.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 77 "memory B-cell: 79.7;naive B-cell: 49.2" "Lineage enriched" "Detected in single" 95 "B-cells: 79.7" "Group enriched" "Detected in some" 16 "Leukemia: 234.7;lymphoma: 729.3" "Breast - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 44: Plasma cells - Antibody production & secretion" "unprognostic (5.28e-1)" "unprognostic (3.56e-3)" "unprognostic (1.00e-2)" "unprognostic (2.28e-2)" "unprognostic (8.30e-2)" "potential prognostic favorable (6.77e-5)" "unprognostic (4.78e-3)" "unprognostic (5.15e-2)" "potential prognostic unfavorable (3.08e-4)" "unprognostic (5.69e-2)" "unprognostic (1.19e-2)" "unprognostic (5.47e-3)" "unprognostic (1.04e-1)" "unprognostic (9.74e-2)" "unprognostic (1.55e-1)" "unprognostic (2.34e-1)" "unprognostic (8.31e-2)" "unprognostic (7.78e-3)" "unprognostic (1.15e-1)" "unprognostic (9.63e-3)" "unprognostic (1.11e-1)" "unprognostic (6.33e-1)" "unprognostic (1.51e-1)" "unprognostic (2.28e-2)" "unprognostic (3.56e-1)" "unprognostic (1.27e-1)" IGLV4-69 ENSG00000211637 "Immunoglobulin lambda variable 4-69" A0A075B6H9 22 22030934-22031472 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 404.1;lymphoid tissue: 430.5;salivary gland: 109.6;stomach 1: 268.9;urinary bladder: 191.7" "Group enriched" "Detected in some" 10 "Gastric chief cells: 9.8;Plasma cells: 37.4" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in single" 4 "medulla oblongata: 2.1" "Group enriched" "Detected in some" 301 "memory B-cell: 333.0;naive B-cell: 225.3" "Lineage enriched" "Detected in single" 359 "B-cells: 333.0" "Cancer enriched" "Detected in single" 405 "lymphoma: 277.1" "Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 78: Plasma cells - Antibody production & ER-stress response" "unprognostic (9.07e-3)" "potential prognostic favorable (5.85e-5)" "potential prognostic favorable (1.86e-4)" "unprognostic (3.33e-2)" "unprognostic (1.02e-1)" "unprognostic (1.20e-2)" "potential prognostic favorable (8.65e-5)" "unprognostic (3.66e-1)" "unprognostic (4.85e-3)" "unprognostic (4.12e-1)" "unprognostic (1.56e-2)" "unprognostic (3.67e-3)" "unprognostic (1.09e-2)" "unprognostic (1.34e-2)" "unprognostic (9.11e-2)" "unprognostic (1.43e-1)" "unprognostic (7.89e-2)" "unprognostic (2.48e-1)" "unprognostic (2.58e-1)" "unprognostic (7.08e-3)" "unprognostic (9.72e-2)" "potential prognostic favorable (5.83e-4)" "unprognostic (9.22e-2)" "unprognostic (8.80e-2)" "unprognostic (1.45e-1)" "unprognostic (1.73e-1)" "unprognostic (5.50e-2)" "unprognostic (1.26e-1)" IGLV5-37 ENSG00000211654 "Immunoglobulin lambda variable 5-37" A0A075B6J1 22 22427540-22428035 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 5 "gallbladder: 23.2;intestine: 9.8;lymphoid tissue: 38.6;salivary gland: 11.3;stomach 1: 15.5" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Lung Squamous Cell Carcinoma (TCGA): 8.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 54 "memory B-cell: 6.2;naive B-cell: 7.0" "Lineage enriched" "Detected in single" 58 "B-cells: 7.0" "Not detected" "Not detected" "Breast - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 34: B-cells - Unknown function" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" "unprognostic (1.36e-3)" "unprognostic (3.79e-2)" "unprognostic (8.30e-2)" "unprognostic (1.18e-1)" "unprognostic (1.29e-3)" "unprognostic (3.82e-2)" "unprognostic (1.18e-1)" "unprognostic (9.38e-2)" "unprognostic (1.66e-1)" "unprognostic (7.74e-2)" "unprognostic (3.67e-2)" "unprognostic (2.28e-1)" "unprognostic (4.15e-1)" "potential prognostic favorable (3.55e-4)" "unprognostic (1.31e-1)" "unprognostic (1.94e-1)" "unprognostic (3.12e-1)" IGLV5-45 ENSG00000211650 "Immunoglobulin lambda variable 5-45" A0A087WSX0 22 22375986-22376505 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 37.9;intestine: 41.4;lymphoid tissue: 91.3;salivary gland: 47.0" "Cell type enhanced" "Detected in some" "Gastric progenitor cells: 1.3;Plasma cells: 3.9" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "memory B-cell: 1.2;naive B-cell: 1.1" "Lineage enriched" "Detected in single" 11 "B-cells: 1.2" "Cancer enriched" "Detected in single" 16 "Myeloma: 2.2" "Breast - Plasma cells, Colon - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 5: Spleen - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 67: Plasma cells - Plasma cell differentiation" "unprognostic (1.27e-1)" "unprognostic (5.59e-1)" "unprognostic (1.64e-1)" "unprognostic (2.00e-1)" "unprognostic (3.27e-1)" "unprognostic (5.64e-1)" "unprognostic (8.76e-2)" "potential prognostic favorable (4.09e-4)" "unprognostic (6.63e-1)" "unprognostic (7.78e-2)" "unprognostic (3.16e-1)" IGLV5-48 ENSG00000211647 "Immunoglobulin lambda variable 5-48 (non-functional)" A0A075B6I7 22 22352940-22353433 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 3.1;lymphoid tissue: 4.9;urinary bladder: 2.5" "Cell type enriched" "Detected in single" 10 "Plasma cells: 9.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 62 "memory B-cell: 5.4;naive B-cell: 6.8" "Lineage enriched" "Detected in single" 69 "B-cells: 6.8" "Cancer enhanced" "Detected in single" "Myeloma: 1.3" "Breast - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 67: Plasma cells - Plasma cell differentiation" "unprognostic (7.04e-1)" "unprognostic (5.01e-3)" "unprognostic (1.28e-1)" "unprognostic (3.51e-2)" "potential prognostic favorable (9.85e-4)" "unprognostic (2.01e-2)" "unprognostic (1.71e-1)" "unprognostic (3.04e-1)" "unprognostic (5.53e-1)" IGLV5-52 ENSG00000211643 "Immunoglobulin lambda variable 5-52" A0A0A0MRZ9 22 22318727-22319226 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "memory B-cell: 11.7;naive B-cell: 10.3" "Lineage enriched" "Detected in many" 6 "B-cells: 11.7" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 22: Epididymis - Mixed function" "Cluster 34: Non-specific - Mixed function" "Cluster 6: Leukemia - Signal transduction" "unprognostic (1.72e-2)" "unprognostic (1.45e-1)" "unprognostic (2.70e-2)" "unprognostic (5.24e-2)" "unprognostic (2.61e-1)" "unprognostic (2.23e-1)" "unprognostic (6.94e-2)" "unprognostic (2.73e-3)" "unprognostic (1.71e-2)" "unprognostic (2.28e-2)" "unprognostic (8.54e-2)" "unprognostic (7.16e-2)" "potential prognostic unfavorable (1.77e-4)" "unprognostic (5.45e-2)" "unprognostic (7.93e-2)" "unprognostic (2.06e-1)" "unprognostic (2.21e-1)" "unprognostic (1.79e-2)" "unprognostic (4.86e-2)" "unprognostic (3.30e-1)" "unprognostic (4.16e-3)" "unprognostic (1.08e-2)" "unprognostic (1.70e-1)" "unprognostic (1.18e-2)" "unprognostic (4.35e-1)" "unprognostic (1.19e-1)" "unprognostic (1.52e-1)" IGLV6-57 ENSG00000211640 "Immunoglobulin lambda variable 6-57" P01721 22 22195799-22196276 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1687.4;urinary bladder: 633.7" "Cell type enriched" "Detected in some" 44 "Plasma cells: 237.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 11 "memory B-cell: 355.6;naive B-cell: 294.1" "Lineage enriched" "Detected in many" 13 "B-cells: 355.6" "Cancer enriched" "Detected in some" 6 "lymphoma: 204.4" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" HPA028862 Supported "Immunoglobulin genes" Immunity NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 67: Plasma cells - Plasma cell differentiation" 8 "HPA028862: " "unprognostic (2.00e-2)" "potential prognostic favorable (3.05e-6)" "unprognostic (1.18e-1)" "unprognostic (1.07e-1)" "unprognostic (1.56e-1)" "unprognostic (7.07e-3)" "potential prognostic favorable (3.42e-5)" "unprognostic (1.25e-2)" "unprognostic (1.34e-3)" "unprognostic (8.11e-2)" "unprognostic (3.19e-3)" "unprognostic (6.80e-3)" "unprognostic (3.40e-1)" "unprognostic (2.19e-3)" "unprognostic (2.19e-1)" "unprognostic (8.32e-2)" "unprognostic (4.33e-2)" "unprognostic (1.74e-1)" "unprognostic (1.47e-1)" "potential prognostic favorable (4.49e-4)" "unprognostic (1.42e-1)" "unprognostic (1.91e-2)" "unprognostic (1.51e-1)" "unprognostic (3.51e-2)" "unprognostic (9.84e-2)" "unprognostic (1.46e-1)" "unprognostic (1.29e-1)" "unprognostic (2.40e-1)" IGLV7-43 ENSG00000211652 "Immunoglobulin lambda variable 7-43" P04211 22 22395018-22395489 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 151.0;lymphoid tissue: 222.6;stomach 1: 109.1" "Cell type enhanced" "Detected in some" "Gastric chief cells: 1.1;Plasma cells: 1.4" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 324 "memory B-cell: 132.7;naive B-cell: 54.5" "Lineage enriched" "Detected in single" 459 "B-cells: 132.7" "Cancer enhanced" "Detected in single" "lymphoma: 1.8" "Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" HPA003182 Approved "Immunoglobulin genes" Immunity NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 67: Plasma cells - Plasma cell differentiation" "HPA003182: " "unprognostic (9.94e-2)" "potential prognostic favorable (1.68e-5)" "potential prognostic favorable (9.05e-5)" "unprognostic (1.47e-2)" "unprognostic (1.42e-1)" "unprognostic (2.13e-1)" "potential prognostic favorable (2.18e-4)" "unprognostic (1.82e-1)" "unprognostic (1.32e-1)" "unprognostic (7.00e-3)" "unprognostic (2.37e-3)" "unprognostic (8.14e-2)" "unprognostic (1.99e-2)" "unprognostic (1.75e-1)" "unprognostic (1.58e-1)" "unprognostic (1.77e-1)" "unprognostic (1.98e-1)" "unprognostic (1.37e-1)" "unprognostic (4.25e-3)" "unprognostic (4.58e-1)" "unprognostic (3.46e-2)" "unprognostic (2.81e-1)" "unprognostic (4.52e-2)" "unprognostic (1.53e-1)" "unprognostic (4.17e-2)" "unprognostic (1.35e-1)" "unprognostic (4.59e-2)" IGLV7-46 ENSG00000211649 "Immunoglobulin lambda variable 7-46" A0A075B6I9 22 22369614-22370087 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 374.3;lymphoid tissue: 428.6;stomach 1: 235.9;urinary bladder: 417.2" "Cell type enriched" "Detected in some" 5 "Plasma cells: 18.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "hypothalamus: 3.1" "Group enriched" "Detected in some" 378 "memory B-cell: 184.5;naive B-cell: 82.7" "Lineage enriched" "Detected in single" 522 "B-cells: 184.5" "Cancer enriched" "Detected in single" 5 "lymphoma: 2.9" "Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" HPA003182 Approved "Immunoglobulin genes" Immunity NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 44: Plasma cells - Antibody production & secretion" "HPA003182: " "unprognostic (1.63e-1)" "potential prognostic favorable (4.11e-6)" "unprognostic (1.11e-3)" "unprognostic (6.20e-2)" "unprognostic (1.64e-1)" "unprognostic (5.27e-3)" "unprognostic (8.25e-2)" "unprognostic (4.47e-3)" "unprognostic (1.50e-1)" "unprognostic (2.09e-1)" "unprognostic (8.68e-3)" "unprognostic (1.03e-1)" "unprognostic (1.08e-1)" "unprognostic (7.24e-2)" "unprognostic (1.10e-1)" "unprognostic (2.34e-2)" "unprognostic (2.04e-1)" "unprognostic (6.27e-2)" "unprognostic (7.39e-2)" "unprognostic (6.95e-3)" "unprognostic (1.60e-1)" "unprognostic (1.35e-2)" "unprognostic (3.18e-1)" "unprognostic (1.11e-2)" "unprognostic (3.14e-1)" "unprognostic (1.22e-1)" "unprognostic (3.24e-1)" "unprognostic (1.24e-1)" IGLV8-61 ENSG00000211638 "Immunoglobulin lambda variable 8-61" A0A075B6I0 22 22098700-22099212 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 756.2;lymphoid tissue: 916.4" "Cell type enriched" "Detected in some" 8 "Plasma cells: 12.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "cerebral cortex: 3.3;choroid plexus: 1.7;pons: 1.3;spinal cord: 1.3;white matter: 1.6" "Group enriched" "Detected in some" 633 "memory B-cell: 259.2;naive B-cell: 534.4" "Lineage enriched" "Detected in single" 852 "B-cells: 534.4" "Cancer enriched" "Detected in some" 6 "lymphoma: 12.1" "Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Low region specificity" "Detected in all" "Immunoglobulin genes" Immunity NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 44: Plasma cells - Antibody production & secretion" "unprognostic (4.77e-3)" "potential prognostic favorable (1.65e-5)" "potential prognostic favorable (1.23e-4)" "unprognostic (3.04e-2)" "unprognostic (2.82e-1)" "unprognostic (3.79e-2)" "unprognostic (7.19e-2)" "potential prognostic favorable (7.15e-4)" "unprognostic (5.78e-2)" "unprognostic (2.41e-2)" "unprognostic (5.34e-3)" "unprognostic (7.46e-2)" "unprognostic (1.22e-2)" "unprognostic (4.96e-2)" "potential prognostic favorable (8.71e-4)" "unprognostic (7.46e-3)" "unprognostic (1.84e-1)" "unprognostic (1.27e-1)" "unprognostic (2.93e-1)" "unprognostic (1.19e-2)" "unprognostic (1.97e-1)" "unprognostic (2.81e-3)" "unprognostic (3.94e-1)" "unprognostic (2.47e-1)" "unprognostic (8.85e-2)" "unprognostic (1.24e-1)" "unprognostic (1.73e-1)" "unprognostic (1.49e-1)" IGLV9-49 ENSG00000223350 "Immunoglobulin lambda variable 9-49" A0A0B4J1Y8 22 22343187-22343732 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 117.9;lymphoid tissue: 110.6" "Group enriched" "Detected in some" 9 "Plasma cells: 4.0;Tuft cells: 11.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 79.7" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 674 "memory B-cell: 70.6;naive B-cell: 88.6" "Lineage enriched" "Detected in single" 751 "B-cells: 88.6" "Cancer enriched" "Detected in single" 89 "lymphoma: 40.8" "Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 37: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 67: Plasma cells - Plasma cell differentiation" "unprognostic (4.28e-1)" "potential prognostic favorable (9.90e-5)" "unprognostic (1.38e-3)" "unprognostic (3.89e-1)" "unprognostic (5.94e-2)" "potential prognostic favorable (1.94e-5)" "potential prognostic unfavorable (3.18e-4)" "unprognostic (1.23e-1)" "unprognostic (3.10e-3)" "unprognostic (1.50e-1)" "unprognostic (1.68e-2)" "unprognostic (1.47e-2)" "unprognostic (5.48e-2)" "unprognostic (3.06e-2)" "unprognostic (3.00e-2)" "unprognostic (1.64e-1)" "unprognostic (2.34e-1)" "unprognostic (1.33e-2)" "unprognostic (3.56e-1)" "unprognostic (3.67e-2)" "unprognostic (1.07e-1)" "unprognostic (2.64e-1)" "unprognostic (1.48e-1)" "unprognostic (2.40e-1)" "unprognostic (7.64e-2)" "unprognostic (3.94e-1)" IGSF1 "IGCD1, IGDC1, INHBP, KIAA0364, MGC75490, PGSF2" ENSG00000147255 "Immunoglobulin superfamily member 1" Q8N6C5 X 131273506-131578899 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "pituitary gland: 379.9" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 42.5;Corticotrophs: 23.9;Lactotrophs: 119.6;Pituitary stem cells: 219.3;Schwann cells: 21.9;Somatotrophs: 78.4;Thymic myoid cells: 24.5;Thyrotrophs: 61.9" "Cell type enhanced" "Detected in many" "astrocyte: 23.0" "Cancer enriched" "Detected in many" 8 "Thyroid Carcinoma (TCGA): 352.3" "Region enhanced" "Detected in all" "hypothalamus: 153.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 9.0" "Adrenal gland - Adrenal medulla cells, Breast - Breast glandular cells, Pituitary gland - Lactotropes, Stomach - Fibroblasts, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Region enhanced" "Detected in all" "hypothalamus: 144.1" "Low region specificity" "Detected in all" "HPA012732, HPA035582" Enhanced Approved Cytosol "Intracellular and membrane" Receptor NA NA 54000 "Cluster 20: Pituitary gland - Hormone signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 18: Liver cancer - Metabolism" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" Cytosol "HPA012732: , HPA035582: " "unprognostic (1.78e-2)" "unprognostic (2.45e-2)" "unprognostic (2.97e-1)" "unprognostic (1.71e-2)" "unprognostic (8.63e-2)" "unprognostic (1.10e-1)" "unprognostic (4.67e-3)" "unprognostic (1.51e-1)" "unprognostic (7.08e-2)" "unprognostic (1.74e-3)" "unprognostic (1.88e-3)" "unprognostic (1.74e-2)" "unprognostic (2.34e-2)" "unprognostic (3.55e-2)" "unprognostic (1.54e-1)" "unprognostic (4.74e-2)" "unprognostic (9.10e-2)" "unprognostic (9.62e-3)" "unprognostic (2.14e-2)" "unprognostic (2.54e-2)" "unprognostic (3.11e-1)" "unprognostic (1.86e-1)" "unprognostic (1.63e-2)" IGSF10 "CMF608, FLJ25972" ENSG00000152580 "Immunoglobulin superfamily member 10" Q6WRI0 3 151425384-151461061 "Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Osteogenesis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 21.1" "Cell type enhanced" "Detected in many" "Early spermatids: 149.6;Hematopoietic stem cells: 68.4;Late primary spermatocytes: 146.6;Megakaryocyte progenitors: 66.3;Megakaryocytes: 117.5;Microglia: 43.9;Respiratory ciliated cells: 82.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 11.8;Rhabdoid: 9.2" "Colon - Fibroblasts, Liver - Hepatic stellate cells, Minor Salivary Gland - Fibroblasts, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" "HPA012655, HPA012921" Uncertain Approved Vesicles "Secreted - unknown location" "Developmental protein" NA NA 15000 "Cluster 75: Ovary - Mixed function" "Cluster 29: Forebrain - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 108: Fibroblasts - ECM organization" 1 Vesicles "HPA012655: , HPA012921: " "unprognostic (9.48e-3)" "unprognostic (8.27e-2)" "unprognostic (1.33e-1)" "unprognostic (1.29e-1)" "unprognostic (5.35e-3)" "unprognostic (3.40e-2)" "unprognostic (2.08e-1)" "unprognostic (2.38e-1)" "unprognostic (2.20e-1)" IGSF11 "BT-IgSF, CT119, Igsf13, MGC35227, VSIG3" ENSG00000144847 "Immunoglobulin superfamily member 11" Q5DX21 3 118900557-119146068 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Growth regulation" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.2;retina: 46.9;testis: 33.4" "Cell type enhanced" "Detected in many" "Astrocytes: 292.9;Bergmann glia: 243.7;Cone photoreceptor cells: 484.4;Early spermatids: 633.3;Endometrial luminal cells: 198.6;Ependymal cells: 200.6;Late primary spermatocytes: 280.4;Late spermatids: 533.6;Oligodendrocytes: 449.8;Rod photoreceptor cells: 271.7" "Cell type enhanced" "Detected in all" "oligodendrocyte: 589.6" "Group enriched" "Detected in many" 6 "Glioblastoma Multiforme (TCGA): 23.1;Skin Cutaneous Melanoma (TCGA): 25.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Myeloma: 4.9;skin cancer: 17.6" "Adrenal gland - Adrenal cortex cells, Colon - Enteric glia cells, Kidney - Proximal tubular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046377 Uncertain Approved "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" "Cell Junctions" "Nucleoplasm, Cytosol" "HPA046377: " "unprognostic (8.34e-2)" "unprognostic (7.11e-2)" "unprognostic (1.21e-1)" "unprognostic (4.00e-3)" "unprognostic (3.84e-1)" "unprognostic (2.71e-3)" "unprognostic (8.67e-2)" "unprognostic (5.17e-2)" "unprognostic (4.24e-2)" "unprognostic (1.39e-1)" "unprognostic (1.27e-1)" "unprognostic (3.17e-1)" "unprognostic (2.27e-1)" IGSF21 "MGC15730, RP11-121A23.1" ENSG00000117154 "Immunoglobin superfamily member 21" Q96ID5 1 18107798-18378483 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 97.3" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 53.2;Brain excitatory neurons: 121.5;Kupffer cells: 60.5;Macrophages: 119.8;Microglia: 313.0;Oligodendrocyte progenitor cells: 257.3;Retinal bipolar cells: 333.1;Tuft cells: 196.0" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 431.0;oligodendrocyte precursor cell: 313.8" "Group enriched" "Detected in many" 5 "Breast Invasive Carcinoma (TCGA): 8.8;Glioblastoma Multiforme (TCGA): 21.5;Prostate Adenocarcinoma (TCGA): 7.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 3.6;lung cancer: 3.4;thyroid cancer: 7.6" "Adipose subcutaneous - Macrophages, Breast - Breast glandular cells, Heart muscle - Macrophages, Kidney - Macrophages, Pancreas - Macrophages, Pituitary gland - Macrophages, Spleen - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" "No annotated function" NA NA 27000 "Cluster 27: Cerebellum - Synaptic function" "Cluster 37: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "unprognostic (4.03e-2)" "unprognostic (1.64e-1)" "unprognostic (3.79e-2)" "unprognostic (3.17e-3)" "unprognostic (1.83e-1)" "potential prognostic favorable (2.48e-4)" "unprognostic (1.34e-1)" "unprognostic (7.76e-2)" "unprognostic (8.08e-2)" "unprognostic (7.71e-2)" "unprognostic (3.22e-1)" "unprognostic (1.19e-1)" "unprognostic (1.43e-2)" "potential prognostic unfavorable (8.31e-4)" "potential prognostic unfavorable (2.61e-4)" "unprognostic (9.42e-2)" "unprognostic (4.05e-2)" "unprognostic (3.11e-1)" "unprognostic (1.10e-1)" "unprognostic (2.68e-2)" IGSF22 "FLJ37794, IGFN2" ENSG00000179057 "Immunoglobulin superfamily member 22" Q8N9C0 11 18704312-18726230 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "skin 1: 1.0" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 21.3;Breast hormone-responsive cells: 11.1;Epididymal principal cells: 10.8;Late spermatids: 10.7;Pancreatic islet cells: 14.1" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "Rhabdoid: 1.3" "Breast - Breast glandular cells, Breast - Breast glandular cells, Skin - Keratinocyte (granular)" "CAB026459, HPA037851" Uncertain Approved Mitochondria NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" Mitochondria "CAB026459: , HPA037851: " "unprognostic (9.66e-2)" "unprognostic (3.88e-1)" IGSF23 ENSG00000216588 "Immunoglobulin superfamily member 23" A1L1A6 19 44613563-44636781 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "intestine: 14.9;liver: 22.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 16.3;Cholangiocytes: 11.8;Early spermatids: 48.7;Enterocytes: 76.8;Hepatocytes: 43.7;Late spermatids: 23.1;Pancreatic duct cells: 19.8;Paneth cells: 11.6;Retinal bipolar cells: 25.0;Tuft cells: 11.5" "Cell type enhanced" "Detected in some" "Bergmann glia: 6.5;cerebellar inhibitory: 6.6" "Cancer enriched" "Detected in many" 8 "Liver Hepatocellular Carcinoma (TCGA): 26.3" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 5 "neutrophil: 2.4" "Lineage enriched" "Detected in single" 5 "granulocytes: 2.4" "Cancer enhanced" "Detected in some" "Kidney cancer: 4.4" "Pancreas - Ductal cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA051811 Approved "Nucleoplasm,Cell Junctions" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 93: Hepatocytes - Bile production & excretion" Nucleoplasm "Cell Junctions" "HPA051811: " "unprognostic (2.52e-1)" "unprognostic (4.09e-3)" "unprognostic (1.26e-3)" "potential prognostic favorable (4.00e-5)" "unprognostic (1.57e-3)" "unprognostic (3.82e-2)" "unprognostic (1.79e-1)" "unprognostic (3.57e-2)" "unprognostic (1.50e-1)" "unprognostic (5.14e-2)" "unprognostic (3.32e-2)" "unprognostic (1.81e-2)" IGSF3 "EWI-3, MGC117164, V8" ENSG00000143061 "Immunoglobulin superfamily member 3" O75054 1 116574399-116667755 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 118.5;Suprabasal keratinocytes: 75.0;Tuft cells: 207.5" "Cell type enriched" "Detected in many" 4 "midbrain-derived inhibitory: 215.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Kidney - Macrophages, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036305, HPA036306" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 85: Squamous epithelial cells - Keratinization" 11 Nucleoplasm Cytosol "HPA036305: , HPA036306: " "unprognostic (7.79e-2)" "unprognostic (9.94e-2)" "unprognostic (7.94e-2)" "unprognostic (3.30e-1)" "unprognostic (5.12e-3)" "unprognostic (1.35e-1)" "unprognostic (2.92e-1)" "unprognostic (8.23e-2)" "unprognostic (1.80e-1)" "unprognostic (3.18e-1)" "validated prognostic favorable (1.55e-4)" "validated prognostic favorable (7.96e-5)" "unprognostic (8.90e-2)" "validated prognostic unfavorable (1.95e-5)" "validated prognostic unfavorable (9.37e-4)" "unprognostic (1.21e-1)" "unprognostic (1.31e-1)" "unprognostic (3.39e-1)" "unprognostic (2.47e-1)" "unprognostic (3.13e-1)" "unprognostic (8.76e-3)" "potential prognostic unfavorable (7.00e-4)" "unprognostic (1.17e-1)" "unprognostic (1.40e-1)" "unprognostic (8.22e-2)" "unprognostic (2.25e-1)" "unprognostic (4.10e-1)" "unprognostic (1.21e-1)" "unprognostic (5.63e-2)" "unprognostic (3.17e-1)" "unprognostic (2.30e-2)" IGSF5 JAM4 ENSG00000183067 "Immunoglobulin superfamily member 5" Q9NSI5 21 39745183-39802081 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enriched" "Detected in many" 10 "Syncytiotrophoblasts: 304.9" "Cell type enhanced" "Detected in many" "medium spiny neuron: 53.8" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 4.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells (progenitors), Heart muscle - Cardiomyocytes, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells" HPA057282 Uncertain Approved "Focal adhesion sites" NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 56: Non-specific - Sensory perception" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" "Focal adhesion sites" "HPA057282: " "unprognostic (3.93e-2)" "unprognostic (1.28e-2)" "unprognostic (1.74e-1)" "unprognostic (1.39e-2)" "potential prognostic favorable (7.16e-4)" "unprognostic (1.52e-1)" "unprognostic (1.72e-1)" "unprognostic (6.85e-2)" IGSF6 DORA ENSG00000140749 "Immunoglobulin superfamily member 6" O95976 16 21639550-21652608 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 28.5" "Cell type enhanced" "Detected in some" "cDC: 109.8;Hofbauer cells: 188.3;Kupffer cells: 230.6;Macrophages: 129.3;Microglia: 120.1;Monocyte progenitors: 54.1;monocytes: 120.7;Neutrophils: 371.6" "Cell type enriched" "Detected in all" 10 "central nervous system macrophage: 152.0" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 7.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 1230.0" "Lineage enhanced" "Detected in all" "granulocytes: 1230.0" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Minor Salivary Gland - Macrophages, Spleen - Macrophages, Stomach - Macrophages" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA041023, HPA041072" Uncertain NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" "HPA041023: , HPA041072: " "unprognostic (6.85e-2)" "unprognostic (1.79e-1)" "unprognostic (6.38e-3)" "unprognostic (2.43e-2)" "unprognostic (1.10e-1)" "unprognostic (3.53e-3)" "unprognostic (4.78e-2)" "unprognostic (5.80e-2)" "unprognostic (6.65e-3)" "unprognostic (3.53e-2)" "unprognostic (3.37e-1)" "unprognostic (3.95e-2)" "unprognostic (1.49e-2)" "unprognostic (1.03e-1)" "unprognostic (1.22e-1)" "unprognostic (2.51e-1)" "unprognostic (5.59e-2)" "unprognostic (1.46e-1)" "unprognostic (1.35e-1)" "unprognostic (1.68e-2)" IGSF8 "CD316, CD81P3, EWI2, PGRL" ENSG00000162729 "Immunoglobulin superfamily member 8" Q969P0 1 160091340-160098943 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 153.9" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 307.7;Müller glia: 92.6;Oligodendrocytes: 127.0;Syncytiotrophoblasts: 86.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011917, HPA075970" Approved Supported Vesicles NA NA 320000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 53: Neurons - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 14 Vesicles "HPA011917: , HPA075970: " "unprognostic (2.23e-2)" "unprognostic (1.50e-1)" "unprognostic (4.26e-3)" "unprognostic (1.08e-3)" "unprognostic (1.13e-3)" "unprognostic (6.71e-3)" "unprognostic (2.18e-1)" "unprognostic (3.71e-1)" "unprognostic (2.15e-1)" "unprognostic (9.93e-2)" "potential prognostic favorable (6.88e-4)" "unprognostic (2.52e-2)" "unprognostic (3.22e-2)" "unprognostic (1.74e-1)" "potential prognostic favorable (4.24e-4)" "unprognostic (2.97e-2)" "unprognostic (1.02e-1)" "unprognostic (3.78e-2)" "unprognostic (8.70e-2)" "unprognostic (1.95e-2)" "unprognostic (2.86e-1)" "unprognostic (1.01e-1)" "unprognostic (1.93e-2)" "unprognostic (1.34e-1)" "unprognostic (1.59e-1)" "unprognostic (2.47e-1)" "unprognostic (3.75e-2)" "unprognostic (4.10e-2)" "unprognostic (1.45e-1)" "unprognostic (7.72e-2)" "unprognostic (6.89e-2)" IGSF9 "IGSF9A, KIAA1355, Nrt1" ENSG00000085552 "Immunoglobulin superfamily member 9" Q9P2J2 1 159927039-159945613 "Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 26.0;retina: 26.2;skin 1: 22.1" "Cell type enhanced" "Detected in many" "Colonocytes: 61.8;Cone photoreceptor cells: 49.7;Early spermatids: 52.8;Enterocytes: 27.0;Foveolar cells: 80.7;Hepatocytes: 28.8;Late spermatids: 44.5;Mesothelial cells: 28.5;Rod photoreceptor cells: 121.0" "Cell type enhanced" "Detected in some" "ependymal cell: 1.6;lower rhombic lip: 3.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Stomach - Gastric mucous cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "basal ganglia: 3.9;cerebellum: 7.5" HPA037753 Uncertain NA NA "Cluster 77: Intestine - Digestion" "Cluster 46: Brainstem - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 2 "HPA037753: " "unprognostic (2.95e-1)" "unprognostic (1.54e-1)" "unprognostic (7.41e-3)" "unprognostic (3.80e-1)" "unprognostic (5.85e-2)" "unprognostic (2.42e-1)" "unprognostic (1.53e-1)" "unprognostic (3.33e-2)" "unprognostic (3.68e-3)" "unprognostic (3.44e-1)" "unprognostic (3.60e-2)" "unprognostic (3.98e-2)" "unprognostic (1.19e-2)" "unprognostic (5.50e-3)" "unprognostic (1.00e-2)" "potential prognostic favorable (2.81e-4)" "unprognostic (6.29e-2)" "unprognostic (2.26e-3)" "unprognostic (2.96e-3)" "unprognostic (5.81e-2)" "unprognostic (5.08e-2)" "unprognostic (2.72e-1)" "unprognostic (1.19e-2)" "unprognostic (2.39e-1)" "unprognostic (1.89e-1)" "unprognostic (1.15e-1)" "unprognostic (5.50e-2)" IGSF9B "KIAA1030, LINC00947, LOC283174, MIR4697HG" ENSG00000080854 "Immunoglobulin superfamily member 9B" Q9UPX0 11 133896438-133956968 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Neurogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 44.7" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 85.1;Brain excitatory neurons: 64.8;Choroid plexus epithelial cells: 149.6;Corticotrophs: 68.9;Ependymal cells: 103.3;Gonadotrophs: 92.4;Müller glia: 89.5;Oligodendrocyte progenitor cells: 139.3;Pituitary stem cells: 68.3;Retinal amacrine cells: 208.1;Retinal bipolar cells: 92.9;Retinal ganglion cells: 204.7;Retinal horizontal cells: 98.2;Sertoli cells: 148.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 6.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 24.3" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010802 Uncertain Approved "Golgi apparatus,Cell Junctions" NA NA "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "Golgi apparatus, Cell Junctions" "HPA010802: " "unprognostic (4.95e-3)" "unprognostic (2.93e-1)" "unprognostic (6.10e-2)" "unprognostic (1.01e-1)" "unprognostic (3.81e-2)" "unprognostic (2.27e-1)" "unprognostic (1.72e-3)" "unprognostic (1.88e-1)" "unprognostic (2.64e-1)" "unprognostic (2.45e-1)" "unprognostic (1.46e-1)" "unprognostic (1.34e-2)" "potential prognostic favorable (3.82e-5)" "unprognostic (2.65e-1)" "unprognostic (2.11e-1)" "unprognostic (3.08e-3)" IHH "BDA1, HHG2" ENSG00000163501 "Indian hedgehog signaling molecule" Q14623 2 219054424-219060921 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Developmental protein, Hydrolase, Protease, Transferase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "cervix: 4.6;endometrium 1: 13.1;intestine: 17.7;stomach 1: 14.1" "Cell type enhanced" "Detected in some" "Colonocytes: 54.4;Enteric stem cells: 26.6;Enteric transient amplifying cells: 25.7;Enterocytes: 24.2;Epididymal efferent duct absorptive cells: 37.0;Epididymal efferent duct ciliated cells: 30.6;Foveolar cells: 25.0;Goblet cells: 50.7;Neuroendocrine cells: 54.0;Prostatic glandular cells: 12.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 44.2;Rectum Adenocarcinoma (TCGA): 46.7" "Region enriched" "Detected in single" 5 "cerebral cortex: 5.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 13.8;Gastric cancer: 11.1;liver cancer: 7.1" "Colon - Colon enterocytes, Prostate - Prostate glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" "Developmental protein" NA NA 2300000 "Cluster 77: Intestine - Digestion" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" 1 "unprognostic (1.75e-1)" "unprognostic (4.48e-2)" "unprognostic (2.49e-2)" "unprognostic (1.85e-1)" "unprognostic (1.24e-3)" "unprognostic (1.08e-2)" "unprognostic (2.61e-1)" "potential prognostic favorable (4.28e-4)" "unprognostic (1.64e-1)" "potential prognostic unfavorable (6.24e-5)" "unprognostic (2.53e-2)" "unprognostic (2.53e-1)" "unprognostic (3.32e-2)" "unprognostic (1.15e-3)" "unprognostic (1.74e-2)" "potential prognostic favorable (2.78e-4)" "unprognostic (2.63e-2)" "unprognostic (4.92e-1)" "unprognostic (1.44e-1)" "unprognostic (2.92e-3)" IHO1 "CCDC36, CT74, FLJ25320, LELA1" ENSG00000173421 "Interactor of HORMAD1 1" Q8IYA8 3 49198428-49258106 "Predicted intracellular proteins" "Differentiation, DNA recombination, Meiosis, Oogenesis, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "testis: 24.1" "Cell type enhanced" "Detected in many" "Adipocytes: 136.1;Choroid plexus epithelial cells: 73.7;Early primary spermatocytes: 424.7;Early spermatids: 68.9;Fibro-adipogenic progenitors: 50.5;Late primary spermatocytes: 125.4;Late spermatids: 57.2;Myonuclei: 81.6" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 55.2;fibroblast: 33.8" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in all" 4 "choroid plexus: 17.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 1.5" "Testis - Early spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA045690, HPA069534" Approved Approved Nucleoplasm NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 4: Non-specific - Transcription" "Cluster 3: Early primary spermatocytes - Early meiosis" 66 Nucleoplasm "HPA045690: , HPA069534: " "unprognostic (3.43e-2)" "unprognostic (1.99e-2)" "unprognostic (2.20e-1)" "unprognostic (3.56e-2)" "unprognostic (3.25e-1)" "unprognostic (1.34e-1)" IK "RED, RER" ENSG00000113141 "IK cytokine" Q13123 5 140647058-140662480 "Essential proteins, Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 373.9;Endometrial ciliated cells: 508.0;Epididymal efferent duct ciliated cells: 448.7;Esophageal apical cells: 432.1;Fallopian tube ciliated cells: 913.2;Late primary spermatocytes: 731.6;Oocytes: 359.2;Respiratory ciliated cells: 651.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048798 Supported Enhanced "Nuclear speckles" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 39: Testis - Nuclear processes" "Cluster 6: Non-specific - Immune response" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 107: Ciliated cells - Cilia assembly & function" 61 "Nuclear speckles" "HPA048798: " "unprognostic (1.94e-2)" "unprognostic (6.82e-2)" "unprognostic (3.67e-2)" "unprognostic (1.88e-1)" "unprognostic (2.05e-1)" "unprognostic (1.59e-1)" "unprognostic (5.69e-1)" "unprognostic (1.01e-1)" "unprognostic (7.75e-2)" "unprognostic (4.62e-3)" "validated prognostic favorable (6.45e-4)" "validated prognostic favorable (9.27e-6)" "unprognostic (6.01e-2)" "potential prognostic unfavorable (1.86e-6)" "unprognostic (1.68e-1)" "unprognostic (2.52e-2)" "unprognostic (1.22e-1)" "unprognostic (2.61e-1)" "unprognostic (1.31e-1)" "unprognostic (1.31e-1)" "unprognostic (7.83e-3)" "unprognostic (1.53e-1)" "unprognostic (6.40e-2)" "unprognostic (1.50e-1)" "unprognostic (1.44e-1)" "unprognostic (2.94e-2)" "unprognostic (1.18e-1)" "unprognostic (2.79e-1)" "unprognostic (8.14e-2)" "unprognostic (9.72e-2)" "unprognostic (7.04e-2)" IKBIP "FLJ31051, IKIP" ENSG00000166130 "IKBKB interacting protein" Q70UQ0 12 98613405-98645113 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 98.2;Neutrophils: 165.6;Plasma cells: 107.5" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 72.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 28.1" "Lineage enriched" "Detected in all" 4 "granulocytes: 28.1" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038677, HPA038678, HPA061541" Enhanced Supported "Nucleoli rim,Endoplasmic reticulum,Mitochondria" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 108: Fibroblasts - ECM organization" 19 "Endoplasmic reticulum" "Nucleoli rim, Mitochondria" "HPA038677: , HPA038678: , HPA061541: " "unprognostic (3.39e-2)" "unprognostic (3.17e-1)" "unprognostic (2.03e-1)" "potential prognostic unfavorable (6.69e-4)" "unprognostic (1.19e-1)" "unprognostic (8.91e-2)" "unprognostic (1.05e-3)" "unprognostic (1.12e-3)" "unprognostic (1.08e-3)" "unprognostic (6.14e-2)" "potential prognostic unfavorable (1.67e-4)" "unprognostic (7.05e-3)" "unprognostic (2.17e-3)" "validated prognostic unfavorable (2.98e-4)" "validated prognostic unfavorable (3.20e-4)" "potential prognostic unfavorable (7.35e-4)" "unprognostic (1.20e-3)" "unprognostic (1.46e-1)" "unprognostic (8.57e-2)" "unprognostic (1.56e-1)" "unprognostic (7.48e-3)" "unprognostic (1.55e-1)" "unprognostic (1.15e-3)" "unprognostic (2.07e-1)" "unprognostic (1.16e-1)" "unprognostic (9.72e-3)" "unprognostic (1.67e-1)" "unprognostic (2.98e-3)" "unprognostic (1.62e-1)" "unprognostic (7.26e-2)" "unprognostic (1.95e-1)" IKBKB "IKK-beta, IKK2, IKKB, NFKBIKB" ENSG00000104365 "Inhibitor of nuclear factor kappa B kinase subunit beta" O14920 8 42271302-42332460 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Host-virus interaction" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cell type enhanced" "Detected in all" "endothelial cell: 229.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001249, CAB004447" Enhanced Supported Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 131 Cytosol "CAB004447: , HPA001249: " "unprognostic (2.84e-2)" "unprognostic (1.30e-2)" "unprognostic (1.92e-1)" "unprognostic (2.53e-1)" "unprognostic (1.65e-1)" "unprognostic (1.64e-2)" "unprognostic (1.01e-1)" "unprognostic (2.16e-3)" "unprognostic (1.06e-2)" "unprognostic (2.40e-1)" "potential prognostic favorable (1.60e-5)" "unprognostic (7.36e-2)" "unprognostic (7.26e-2)" "unprognostic (3.51e-2)" "unprognostic (3.78e-2)" "unprognostic (2.38e-1)" "unprognostic (3.01e-3)" "unprognostic (2.99e-1)" "unprognostic (2.79e-2)" "unprognostic (3.55e-2)" "unprognostic (3.10e-1)" "unprognostic (2.64e-2)" "unprognostic (7.15e-2)" "unprognostic (1.25e-1)" "unprognostic (5.38e-1)" "unprognostic (1.01e-2)" "unprognostic (2.33e-1)" "unprognostic (1.62e-2)" "unprognostic (1.02e-1)" "unprognostic (1.90e-1)" "unprognostic (7.52e-2)" IKBKE "IKK-i, IKKE, KIAA0151" ENSG00000263528 "Inhibitor of nuclear factor kappa B kinase subunit epsilon" Q14164 1 206470476-206496889 "Enzymes, Predicted intracellular proteins" "DNA damage, Host-virus interaction" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 22.7" "Cell type enhanced" "Detected in many" "Esophageal suprabasal cells: 47.5;Foveolar cells: 27.8" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 25.1;leukocyte: 25.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA015788, CAB025983" Approved Supported Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 38: Sub-cortical - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 9: T-cells - Adaptive immunity: Regulation" 51 Cytosol "CAB025983: , HPA015788: " "unprognostic (2.93e-2)" "unprognostic (8.24e-2)" "potential prognostic favorable (2.26e-4)" "unprognostic (8.61e-2)" "unprognostic (1.70e-1)" "unprognostic (2.87e-1)" "unprognostic (6.56e-3)" "unprognostic (2.63e-1)" "unprognostic (5.93e-3)" "potential prognostic unfavorable (3.30e-6)" "unprognostic (3.89e-2)" "unprognostic (7.42e-2)" "unprognostic (2.84e-3)" "unprognostic (2.13e-2)" "unprognostic (9.92e-2)" "unprognostic (6.89e-3)" "unprognostic (9.25e-2)" "unprognostic (6.77e-2)" "unprognostic (2.45e-1)" "unprognostic (1.69e-1)" "unprognostic (2.35e-1)" "unprognostic (1.29e-1)" "unprognostic (1.05e-1)" "unprognostic (1.17e-2)" "unprognostic (2.77e-2)" "unprognostic (2.62e-2)" "unprognostic (7.46e-3)" "unprognostic (3.38e-1)" IKBKG "FIP-3, FIP3, Fip3p, IKK-gamma, IKKAP1, IKKG, IP1, IP2, NEMO, ZC2HC9" ENSG00000269335 "Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma" Q9Y6K9 X 154541199-154565046 "Disease related genes, Human disease related genes, Predicted intracellular proteins, RAS pathway related proteins" "DNA damage, Host-virus interaction, Transcription, Transcription regulation" "Disease variant, Ectodermal dysplasia, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 11.4;Platelets: 15.5;Retinal horizontal cells: 10.0;Rod photoreceptor cells: 9.7;Tuft cells: 23.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000426, CAB010373" Uncertain Enhanced Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 36: Non-specific - mRNA processing" "Cluster 65: Non-specific - Cell growth & division" 209 Cytosol "CAB010373: , HPA000426: " "unprognostic (2.53e-2)" "unprognostic (1.25e-1)" "unprognostic (4.07e-2)" "unprognostic (1.33e-3)" "unprognostic (1.31e-3)" "unprognostic (2.85e-2)" "unprognostic (1.51e-2)" "unprognostic (2.70e-1)" "unprognostic (1.12e-1)" "unprognostic (1.55e-2)" "unprognostic (3.36e-2)" "unprognostic (3.40e-1)" "unprognostic (2.22e-2)" "unprognostic (4.37e-2)" "unprognostic (1.92e-1)" "unprognostic (6.40e-3)" "unprognostic (4.74e-2)" "unprognostic (6.68e-2)" "unprognostic (1.91e-1)" "unprognostic (2.18e-2)" "unprognostic (2.43e-2)" "unprognostic (7.15e-2)" "unprognostic (6.16e-2)" "unprognostic (2.59e-3)" "unprognostic (1.81e-1)" "unprognostic (2.30e-1)" "unprognostic (9.16e-2)" "unprognostic (7.69e-2)" IKZF1 "hIk-1, Hs.54452, IKAROS, LyF-1, PPP1R92, ZNFN1A1" ENSG00000185811 "IKAROS family zinc finger 1" Q13422 7 50304068-50405101 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "bone marrow: 160.4;lymphoid tissue: 99.0" "Cell type enhanced" "Detected in many" "B-cells: 398.1;Erythrocyte progenitors: 256.6;Hematopoietic stem cells: 476.0;Innate lymphoid cells: 478.1;Mast cells: 347.8;Megakaryocyte-Erythroid progenitors: 281.4;Microglia: 498.3;Monocyte progenitors: 380.4;monocytes: 257.2;Neutrophil progenitors: 1672.8;Neutrophils: 694.8;NK-cells: 596.0;pDCs: 352.0;Plasma cells: 261.3;T-cells: 675.2;Thymocytes: 747.8" "Group enriched" "Detected in many" 72 "central nervous system macrophage: 628.5;leukocyte: 1007.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 104 "Leukemia: 88.6;lymphoma: 129.9;Myeloma: 44.5" "Adipose visceral - T-cells, Skeletal muscle - Macrophages, Stomach - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB009247, HPA035221, HPA035222" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 92 Nucleoplasm Cytosol "CAB009247: , HPA035221: , HPA035222: " "unprognostic (8.60e-3)" "unprognostic (3.09e-3)" "potential prognostic favorable (2.42e-4)" "unprognostic (9.08e-3)" "unprognostic (5.21e-2)" "unprognostic (3.84e-1)" "unprognostic (3.38e-1)" "unprognostic (2.97e-2)" "potential prognostic favorable (6.63e-5)" "unprognostic (1.16e-1)" "unprognostic (4.00e-3)" "unprognostic (3.04e-2)" "unprognostic (5.24e-2)" "unprognostic (4.47e-2)" "unprognostic (3.75e-2)" "potential prognostic favorable (1.77e-4)" "unprognostic (1.01e-1)" "unprognostic (4.18e-1)" "unprognostic (4.31e-1)" "unprognostic (4.24e-1)" "unprognostic (3.95e-1)" "unprognostic (1.42e-1)" "unprognostic (7.09e-2)" "unprognostic (2.88e-1)" "unprognostic (3.96e-2)" "unprognostic (2.52e-2)" "unprognostic (4.41e-3)" "unprognostic (1.65e-1)" "unprognostic (4.79e-2)" "unprognostic (9.34e-2)" "unprognostic (7.63e-3)" IKZF2 "Helios, ZNFN1A2" ENSG00000030419 "IKAROS family zinc finger 2" Q9UKS7 2 212999691-213152427 "Predicted intracellular proteins, Transcription factors" "Hearing, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 38.3" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 563.2;Ocular epithelial cells: 531.3;Papillary tip epithelial cells: 387.9;Prostatic hillock cells: 259.2;Urothelial cells: 286.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 13.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "granulocytes: 4.8;NK-cells: 5.8;T-cells: 5.9" "Cancer enhanced" "Detected in many" "Leukemia: 31.1;lymphoma: 32.5" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA059142 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 80: Thymus - Adaptive immune response" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 100: Stratified epithelial cells - Barrier functions" 7 "Nucleoplasm, Nuclear bodies" Cytosol "HPA059142: " "unprognostic (4.57e-3)" "unprognostic (3.73e-1)" "unprognostic (4.38e-1)" "unprognostic (2.06e-1)" "unprognostic (2.35e-1)" "unprognostic (2.51e-2)" "unprognostic (6.06e-2)" "unprognostic (1.05e-1)" "unprognostic (3.12e-3)" "potential prognostic favorable (4.99e-4)" "unprognostic (5.97e-3)" "unprognostic (2.44e-2)" "unprognostic (7.28e-2)" "unprognostic (7.16e-2)" "unprognostic (4.17e-3)" "unprognostic (3.59e-1)" "unprognostic (3.56e-2)" "unprognostic (2.20e-1)" "unprognostic (5.62e-2)" "unprognostic (7.55e-2)" "unprognostic (2.44e-2)" "unprognostic (4.90e-2)" "unprognostic (8.82e-2)" "unprognostic (1.12e-1)" "unprognostic (3.33e-1)" "potential prognostic favorable (4.68e-4)" "unprognostic (5.57e-2)" IKZF3 "Aiolos, ZNFN1A3" ENSG00000161405 "IKAROS family zinc finger 3" Q9UKT9 17 39757718-39864312 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "B-cell activation, Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 11.1;lymphoid tissue: 38.4" "Group enriched" "Detected in many" 7 "B-cells: 402.3;Mast cells: 165.0;NK-cells: 309.7;Plasma cells: 207.3;T-cells: 314.3" "Cell type enriched" "Detected in some" 48 "leukocyte: 417.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 13.2;T-cells: 28.8" "Group enriched" "Detected in some" 7 "lymphoma: 42.4;Myeloma: 33.3" "Adipose subcutaneous - T-cells, Adrenal gland - T-cells, Colon - T-cells, Heart muscle - T-cells, Lung - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Skin - T-cells, Spleen - B-cells (Spleen), Stomach - T-cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA024377, HPA073266" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 157 Nucleoplasm Cytosol "HPA024377: , HPA073266: " "potential prognostic favorable (8.02e-4)" "unprognostic (2.12e-2)" "unprognostic (7.81e-2)" "unprognostic (3.47e-3)" "unprognostic (2.26e-1)" "unprognostic (4.10e-2)" "unprognostic (3.24e-1)" "unprognostic (1.06e-3)" "unprognostic (1.48e-1)" "unprognostic (2.41e-1)" "unprognostic (2.28e-2)" "potential prognostic favorable (8.07e-5)" "unprognostic (2.06e-1)" "unprognostic (1.03e-1)" "unprognostic (1.22e-1)" "unprognostic (4.22e-2)" "unprognostic (7.62e-2)" "unprognostic (9.32e-3)" "unprognostic (2.34e-1)" "unprognostic (1.23e-3)" "unprognostic (6.44e-2)" "unprognostic (3.89e-2)" "unprognostic (1.44e-1)" "unprognostic (1.62e-1)" "unprognostic (1.21e-1)" "unprognostic (9.58e-2)" IKZF4 "Eos, ZNFN1A4" ENSG00000123411 "IKAROS family zinc finger 4" Q9H2S9 12 56007659-56038435 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "T-reg: 1.9" "Lineage enriched" "Detected in single" 12 "T-cells: 1.9" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046270, HPA049016" Approved Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 25: Non-specific - Transcription" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 103: Non-specific - Basic cellular processes" 14 "Nucleoplasm, Nuclear bodies" "HPA046270: , HPA049016: " "unprognostic (9.34e-3)" "unprognostic (3.01e-2)" "unprognostic (7.83e-2)" "unprognostic (6.43e-2)" "unprognostic (1.29e-1)" "unprognostic (1.31e-2)" "unprognostic (9.91e-2)" "unprognostic (4.33e-1)" "unprognostic (4.69e-3)" "unprognostic (3.17e-1)" "unprognostic (4.02e-2)" "unprognostic (1.08e-1)" "unprognostic (3.91e-2)" "unprognostic (9.12e-2)" "potential prognostic favorable (9.50e-4)" "unprognostic (1.01e-1)" "unprognostic (1.64e-1)" "unprognostic (1.17e-2)" "unprognostic (3.62e-1)" "unprognostic (7.05e-3)" "unprognostic (3.43e-3)" "unprognostic (2.90e-2)" "unprognostic (1.34e-1)" "unprognostic (3.67e-1)" "unprognostic (1.03e-1)" "unprognostic (6.77e-2)" "unprognostic (1.95e-1)" "unprognostic (1.22e-1)" "unprognostic (3.76e-2)" "unprognostic (1.28e-2)" IKZF5 "FLJ22973, Pegasus, ZNFN1A5" ENSG00000095574 "IKAROS family zinc finger 5" Q9H5V7 10 122990807-123008812 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015297, HPA051574" Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 9 Nucleoplasm "Plasma membrane, Cytosol" "HPA015297: , HPA051574: " "unprognostic (6.48e-3)" "unprognostic (4.23e-1)" "unprognostic (2.37e-1)" "unprognostic (4.78e-2)" "unprognostic (5.35e-2)" "unprognostic (2.06e-3)" "unprognostic (1.74e-2)" "unprognostic (4.92e-2)" "unprognostic (1.90e-3)" "unprognostic (2.97e-1)" "validated prognostic favorable (4.80e-7)" "validated prognostic favorable (8.42e-4)" "unprognostic (2.04e-1)" "unprognostic (1.51e-1)" "unprognostic (1.76e-2)" "unprognostic (2.12e-3)" "unprognostic (3.17e-2)" "unprognostic (3.33e-1)" "unprognostic (3.92e-1)" "unprognostic (8.52e-2)" "potential prognostic unfavorable (5.50e-5)" "unprognostic (1.85e-1)" "unprognostic (2.49e-2)" "unprognostic (7.26e-2)" "unprognostic (1.29e-2)" "unprognostic (1.37e-1)" "unprognostic (1.31e-1)" "unprognostic (1.07e-1)" "unprognostic (1.67e-1)" "unprognostic (5.48e-2)" "unprognostic (1.47e-1)" IL10 "CSIF, IL-10, IL10A, TGIF" ENSG00000136634 "Interleukin 10" P22301 1 206767602-206774541 "Cancer-related genes, Candidate cardiovascular disease genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 5.5;lymphoid tissue: 6.5" "Cell type enhanced" "Detected in some" "cDC: 24.7;Hofbauer cells: 31.0;Kupffer cells: 57.4;Macrophages: 94.9;monocytes: 257.9" "Cell type enriched" "Detected in single" 7 "central nervous system macrophage: 6.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "thalamus: 5.7" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.6;intermediate monocyte: 1.3" "Lineage enriched" "Detected in single" 5 "monocytes: 1.6" "Cancer enriched" "Detected in some" 8 "lymphoma: 15.9" "Adipose subcutaneous - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Minor Salivary Gland - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Late spermatids, Thyroid gland - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB013120, HPA071391" Approved "Secreted to blood" Interleukin NA NA 5670 "Cluster 40: Monocytes - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 13 "CAB013120: , HPA071391: " "unprognostic (2.14e-1)" "unprognostic (1.93e-2)" "unprognostic (2.10e-1)" "unprognostic (2.27e-1)" "unprognostic (9.10e-2)" "unprognostic (4.93e-1)" "unprognostic (1.43e-1)" "unprognostic (9.51e-2)" "unprognostic (1.94e-3)" "unprognostic (1.43e-2)" "unprognostic (1.04e-1)" "unprognostic (2.78e-1)" "unprognostic (1.16e-1)" "unprognostic (1.88e-1)" "unprognostic (1.62e-2)" "unprognostic (2.75e-2)" "unprognostic (9.09e-2)" "unprognostic (2.31e-3)" "unprognostic (4.72e-3)" IL10RA "CD210, CD210a, CDW210A, HIL-10R, IL10R" ENSG00000110324 "Interleukin 10 receptor subunit alpha" Q13651 11 117986370-118003037 "CD markers, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 54.5;lymphoid tissue: 71.6" "Cell type enhanced" "Detected in many" "cDC: 186.9;Extravillous trophoblasts: 162.3;Hofbauer cells: 83.9;Kupffer cells: 342.3;Macrophages: 166.4;Microglia: 94.5;monocytes: 232.6;Neutrophils: 206.8;NK-cells: 87.3;pDCs: 108.8;Plasma cells: 87.3;T-cells: 113.9" "Group enriched" "Detected in many" 32 "central nervous system macrophage: 125.7;leukocyte: 186.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "lymphoma: 28.7;Myeloma: 13.1" "Adipose subcutaneous - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Skeletal muscle - Macrophages, Skin - T-cells, Testis - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065647, HPA069086" Supported "Plasma membrane,Primary cilium,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 22: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 30 "Plasma membrane, Cytosol" "Primary cilium" "HPA065647: , HPA069086: " "unprognostic (4.85e-2)" "unprognostic (3.46e-2)" "unprognostic (3.32e-2)" "unprognostic (1.34e-2)" "unprognostic (1.01e-1)" "unprognostic (3.13e-1)" "unprognostic (6.19e-2)" "unprognostic (2.84e-2)" "unprognostic (5.03e-3)" "unprognostic (3.33e-1)" "unprognostic (9.06e-2)" "unprognostic (3.28e-1)" "unprognostic (1.79e-1)" "unprognostic (1.26e-1)" "unprognostic (2.16e-2)" "unprognostic (3.93e-3)" "unprognostic (8.50e-2)" "unprognostic (1.17e-1)" "unprognostic (4.22e-1)" "unprognostic (5.63e-2)" "unprognostic (1.57e-1)" "unprognostic (2.80e-2)" "unprognostic (1.32e-1)" "unprognostic (2.97e-1)" "unprognostic (1.14e-2)" "unprognostic (8.27e-2)" "unprognostic (1.04e-2)" "unprognostic (2.11e-1)" "unprognostic (4.26e-3)" "unprognostic (2.18e-1)" "unprognostic (2.53e-1)" IL10RB "CDW210B, CRF2-4, CRFB4, D21S58, D21S66, IL-10R2" ENSG00000243646 "Interleukin 10 receptor subunit beta" Q08334 21 33266367-33311420 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Antiviral defense" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 51.3;Cytotrophoblasts: 44.8;Enterocytes: 49.9;Extravillous trophoblasts: 46.5;Goblet cells: 39.2;Kupffer cells: 43.0;Neutrophils: 71.5;Syncytiotrophoblasts: 71.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020670, HPA047550" Approved Approved Cytosol NA NA 170000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 6: Non-specific - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 2 Cytosol "CAB020670: , HPA047550: " "unprognostic (1.31e-1)" "unprognostic (2.94e-1)" "unprognostic (1.89e-1)" "unprognostic (2.64e-1)" "unprognostic (3.52e-1)" "unprognostic (4.93e-3)" "unprognostic (1.04e-2)" "unprognostic (6.43e-2)" "unprognostic (1.97e-2)" "unprognostic (1.45e-1)" "unprognostic (5.13e-2)" "unprognostic (2.90e-2)" "unprognostic (1.59e-1)" "unprognostic (4.34e-3)" "unprognostic (5.82e-2)" "unprognostic (6.70e-2)" "unprognostic (1.87e-3)" "unprognostic (1.49e-1)" "unprognostic (5.19e-1)" "unprognostic (2.13e-1)" "unprognostic (2.96e-1)" "unprognostic (1.23e-2)" "unprognostic (2.46e-1)" "unprognostic (2.97e-1)" "unprognostic (2.24e-1)" "unprognostic (8.64e-3)" "unprognostic (4.02e-2)" "unprognostic (2.64e-1)" "unprognostic (1.88e-1)" "unprognostic (8.82e-2)" "unprognostic (2.33e-1)" IL11 "AGIF, IL-11" ENSG00000095752 "Interleukin 11" P20809 19 55364382-55370463 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 7.1" "Cell type enriched" "Detected in some" 5 "Fibroblasts: 62.7" "Cell type enhanced" "Detected in some" "splatter: 3.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Secreted to blood" Interleukin NA NA 34800 "Cluster 71: Cerebellum - Nervous system development" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 72: Neuronal - Signal transduction" "Cluster 17: Non-specific - RNA processing" 6 "unprognostic (7.80e-2)" "unprognostic (4.27e-2)" "unprognostic (1.51e-1)" "potential prognostic unfavorable (3.35e-4)" "unprognostic (2.22e-1)" "unprognostic (3.46e-1)" "unprognostic (1.84e-3)" "unprognostic (3.00e-1)" "unprognostic (2.22e-2)" "unprognostic (8.38e-3)" "unprognostic (7.48e-2)" "unprognostic (1.18e-2)" "unprognostic (1.58e-2)" "unprognostic (1.28e-1)" "validated prognostic unfavorable (9.29e-4)" "validated prognostic unfavorable (8.40e-4)" "unprognostic (1.15e-2)" "unprognostic (2.80e-1)" "unprognostic (2.41e-1)" "unprognostic (3.56e-2)" "unprognostic (1.10e-1)" "unprognostic (9.23e-2)" "unprognostic (1.68e-2)" IL11RA ENSG00000137070 "Interleukin 11 receptor subunit alpha" Q14626 9 34652162-34661902 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Receptor "Craniosynostosis, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 36.3" "Cell type enhanced" "Detected in some" "Astrocytes: 24.6;Bergmann glia: 22.8;Brain excitatory neurons: 7.6;Brain inhibitory neurons: 13.9;Late spermatids: 7.9;Microglia: 8.2;Oligodendrocyte progenitor cells: 8.0;Oligodendrocytes: 9.3;Other brain neurons: 8.4;Podocytes: 15.2;Proximal tubule cells: 17.2;Renal connecting tubule cells: 11.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Neuroblastoma: 14.6" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Cardiomyocytes, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013162, CAB032830, HPA036652, HPA036653" Supported Approved "Vesicles,Plasma membrane" "Secreted to blood" Receptor NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 102: Non-specific - Mixed function" 1 "Vesicles, Plasma membrane" "CAB032830: , HPA013162: , HPA036652: , HPA036653: " "unprognostic (1.71e-1)" "unprognostic (1.91e-1)" "unprognostic (5.88e-2)" "unprognostic (2.81e-2)" "unprognostic (2.32e-2)" "unprognostic (1.49e-2)" "unprognostic (9.19e-2)" "unprognostic (8.27e-2)" "unprognostic (2.77e-2)" "potential prognostic unfavorable (5.81e-5)" "unprognostic (3.87e-2)" "unprognostic (1.65e-1)" "unprognostic (2.57e-2)" "unprognostic (8.82e-2)" "unprognostic (5.17e-3)" "unprognostic (1.38e-3)" "unprognostic (6.81e-2)" "unprognostic (1.22e-1)" "unprognostic (3.02e-2)" "unprognostic (3.19e-1)" "unprognostic (1.69e-2)" "potential prognostic favorable (9.36e-4)" "unprognostic (2.85e-2)" "unprognostic (2.18e-1)" "unprognostic (1.96e-1)" "unprognostic (2.22e-2)" "unprognostic (1.00e-1)" "unprognostic (3.32e-1)" "unprognostic (1.58e-1)" "unprognostic (1.95e-2)" "unprognostic (5.60e-2)" IL12A "CLMF, IL-12A, NFSK, NKSF1, p35" ENSG00000168811 "Interleukin 12A" P29459 3 159988835-159996019 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 4.1" "Cell type enriched" "Detected in some" 5 "Esophageal apical cells: 65.3" "Cell type enhanced" "Detected in some" "astrocyte: 3.1;CGE interneuron: 2.9;LAMP5-LHX6 and Chandelier: 3.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "naive B-cell: 2.2" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebral cortex: 2.6" "Not detected" "Not detected" HPA001886 Uncertain "Secreted to blood" Interleukin NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 84: Apical squamous epithelium - Cornification" 1 "HPA001886: " "unprognostic (1.77e-1)" "potential prognostic favorable (8.32e-4)" "unprognostic (1.62e-1)" "unprognostic (2.02e-1)" "unprognostic (6.06e-2)" "unprognostic (2.14e-1)" "unprognostic (2.79e-1)" "unprognostic (1.03e-2)" "unprognostic (6.74e-2)" "unprognostic (4.62e-2)" IL12B "CLMF, CLMF2, IL-12B, NKSF, NKSF2" ENSG00000113302 "Interleukin 12B" P29460 5 159314780-159330863 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Testicular Germ Cell Tumor (TCGA): 5.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 13 "lymphoma: 4.0" "Minor Salivary Gland - Minor salivary gland ductal cells, Pituitary gland - Somatotropes" "Not detected" "Not detected" "Not detected" "Not detected" HPA040970 Supported "Secreted to blood" Interleukin NA NA 140000 "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 82: Dendritic cells - Antigen presentation" 4 "HPA040970: " "unprognostic (6.32e-2)" "unprognostic (9.15e-2)" "unprognostic (6.01e-2)" IL12RB1 "CD212, IL12RB" ENSG00000096996 "Interleukin 12 receptor subunit beta 1" P42701 19 18058995-18098944 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 22.7" "Cell type enhanced" "Detected in many" "B-cells: 15.2;cDC: 10.4;Endometrial glandular cells: 15.7;Innate lymphoid cells: 14.5;Kupffer cells: 19.5;Macrophages: 13.5;monocytes: 11.8;Neutrophils: 23.8;NK-cells: 29.9;Plasma cells: 12.8;T-cells: 29.2;Thymocytes: 11.0" "Group enriched" "Detected in some" 4 "central nervous system macrophage: 10.3;leukocyte: 21.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 14 "Leukemia: 9.4;lymphoma: 19.8;Myeloma: 26.5" "Adrenal gland - Macrophages, Breast - T-cells, Lung - T-cells, Prostate - T-cells, Skeletal muscle - Macrophages, Skin - T-cells, Thyroid gland - T-cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA074414 Approved "Plasma membrane" "Intracellular and membrane" Receptor NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 11: White matter - Signal transduction" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" "Plasma membrane" "HPA074414: " "unprognostic (1.13e-1)" "unprognostic (1.17e-1)" "unprognostic (6.67e-2)" "unprognostic (8.61e-3)" "unprognostic (2.45e-1)" "unprognostic (1.13e-1)" "unprognostic (1.87e-1)" "unprognostic (4.07e-2)" "potential prognostic favorable (1.36e-4)" "unprognostic (5.13e-1)" "unprognostic (1.35e-1)" "unprognostic (2.20e-1)" "unprognostic (2.02e-1)" "unprognostic (1.28e-1)" "unprognostic (1.27e-1)" "unprognostic (2.68e-2)" "unprognostic (2.36e-1)" "unprognostic (1.40e-1)" "unprognostic (2.98e-1)" "unprognostic (1.94e-1)" "unprognostic (6.75e-2)" "unprognostic (4.09e-2)" "unprognostic (9.32e-2)" "unprognostic (2.26e-1)" "unprognostic (2.13e-2)" "unprognostic (1.53e-2)" "unprognostic (9.17e-2)" "unprognostic (6.88e-2)" "unprognostic (1.70e-2)" "unprognostic (4.14e-2)" "unprognostic (2.54e-2)" IL12RB2 ENSG00000081985 "Interleukin 12 receptor subunit beta 2" Q99665 1 67307364-67398724 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 6.2;skeletal muscle: 3.3" "Cell type enhanced" "Detected in many" "Epicardial cells: 116.0;Epididymal basal cells: 56.9;Hematopoietic stem cells: 104.8;Hofbauer cells: 63.4;Innate lymphoid cells: 84.7;Medullary thymic epithelial cells: 79.2;Myonuclei: 141.7;NK-cells: 355.6;T-cells: 135.9;Thymic myoid cells: 57.1" "Cell type enhanced" "Detected in all" "hippocampal CA1-3: 110.5" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 18.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "gdT-cell: 4.8;NK-cell: 15.9" "Group enriched" "Detected in many" 41 "NK-cells: 15.9;T-cells: 4.8" "Cancer enhanced" "Detected in some" "Leukemia: 4.0;skin cancer: 5.2" "Adipose visceral - Macrophages, Heart muscle - Macrophages, Testis - Early spermatids, Testis - Late spermatids" "Region enhanced" "Detected in single" "olfactory bulb: 1.4" "Low region specificity" "Detected in all" HPA024168 Uncertain Approved "Plasma membrane" "Intracellular and membrane" Receptor NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 51: Neurons - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 2 "Plasma membrane" "HPA024168: " "unprognostic (1.36e-2)" "unprognostic (9.62e-2)" "unprognostic (6.53e-2)" "unprognostic (2.52e-2)" "unprognostic (2.16e-1)" "potential prognostic favorable (8.72e-4)" "unprognostic (7.23e-2)" "unprognostic (2.73e-2)" "potential prognostic favorable (7.44e-4)" "unprognostic (1.63e-1)" "unprognostic (2.35e-1)" "unprognostic (1.76e-2)" "potential prognostic favorable (9.96e-4)" "potential prognostic favorable (7.66e-5)" "unprognostic (2.22e-1)" "unprognostic (4.58e-2)" IL13 "ALRH, BHR1, IL-13, MGC116786, MGC116788, MGC116789, P600" ENSG00000169194 "Interleukin 13" P35225 5 132656263-132661110 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" Cytokine "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 45 "testis: 23.3" "Cell type enhanced" "Detected in some" "Early spermatids: 90.7;Late primary spermatocytes: 138.5;Late spermatids: 375.5;Mast cells: 87.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 45 "lymphoma: 4.8" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" Interleukin NA NA 40000 "Cluster 23: Testis - Spermatogenesis" "Cluster 59: Leukemia - T-cell receptor" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 10 IL13RA1 "CD213a1, IL-13Ra, NR4" ENSG00000131724 "Interleukin 13 receptor subunit alpha 1" P78552 X 118727133-118794535 "CD markers, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "cDC: 279.3;Esophageal apical cells: 542.8;Macrophages: 222.2;Microglia: 309.8;monocytes: 221.7;Neutrophils: 443.5;Tuft cells: 322.8" "Group enriched" "Detected in many" 8 "central nervous system macrophage: 384.0;endothelial cell: 135.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 10.9;eosinophil: 12.1;myeloid DC: 17.2;neutrophil: 29.0" "Group enriched" "Detected in many" 7 "dendritic cells: 17.2;granulocytes: 29.0;monocytes: 10.9" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Skeletal muscle - Endothelial cells, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" Receptor NA NA 2500000 "Cluster 7: Non-specific - Innate immune response" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 44: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" 8 "unprognostic (1.41e-1)" "unprognostic (7.71e-3)" "unprognostic (2.68e-2)" "unprognostic (5.22e-3)" "unprognostic (9.54e-3)" "unprognostic (1.72e-2)" "unprognostic (3.63e-2)" "unprognostic (1.54e-3)" "unprognostic (1.84e-2)" "potential prognostic unfavorable (1.42e-5)" "unprognostic (3.17e-3)" "unprognostic (4.29e-2)" "unprognostic (4.68e-2)" "unprognostic (6.18e-2)" "unprognostic (2.91e-3)" "unprognostic (1.07e-1)" "unprognostic (2.09e-3)" "unprognostic (6.14e-2)" "unprognostic (1.01e-3)" "unprognostic (6.11e-2)" "unprognostic (1.35e-1)" "unprognostic (1.80e-1)" "unprognostic (2.32e-1)" "unprognostic (5.47e-2)" "unprognostic (7.50e-2)" "unprognostic (7.70e-2)" "unprognostic (1.03e-1)" "unprognostic (8.81e-3)" "unprognostic (2.86e-2)" "unprognostic (9.92e-2)" "unprognostic (1.48e-1)" IL13RA2 "CD213a2, CT19, IL-13R, IL13BP" ENSG00000123496 "Interleukin 13 receptor subunit alpha 2" Q14627 X 115003975-115019977 "Cancer-related genes, CD markers, Predicted membrane proteins" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 30.5;testis: 28.0" "Cell type enhanced" "Detected in some" "Early primary spermatocytes: 42.6;Early spermatids: 354.7;Epididymal basal cells: 100.1;Late primary spermatocytes: 184.4;Late spermatids: 69.0" "Cell type enhanced" "Detected in many" "ependymal cell: 14.0" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 34.1" "Region enhanced" "Detected in many" "hypothalamus: 24.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 77.2;Sarcoma: 84.5;skin cancer: 80.6" "Adrenal gland - Adrenal medulla cells, Liver - Sinusoid Endothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids" "Region enhanced" "Detected in many" "olfactory bulb: 7.0" "Low region specificity" "Detected in many" "HPA045831, HPA067363" Approved "Nucleoplasm,Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 72: Neuronal - Signal transduction" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 12 "Plasma membrane, Cell Junctions" "Nucleoplasm, Vesicles" "HPA045831: , HPA067363: " "unprognostic (1.50e-2)" "unprognostic (2.05e-2)" "unprognostic (1.13e-1)" "unprognostic (4.44e-2)" "unprognostic (2.65e-2)" "unprognostic (8.77e-2)" "unprognostic (9.88e-2)" "unprognostic (1.16e-3)" "unprognostic (5.72e-3)" "unprognostic (3.61e-2)" "unprognostic (3.18e-2)" "unprognostic (5.32e-2)" "unprognostic (8.12e-2)" "unprognostic (2.86e-1)" "unprognostic (4.84e-2)" "unprognostic (1.54e-3)" "unprognostic (5.97e-2)" "unprognostic (4.27e-2)" "unprognostic (1.32e-1)" "unprognostic (1.71e-1)" "unprognostic (7.36e-2)" "unprognostic (1.94e-1)" "unprognostic (2.32e-1)" "unprognostic (9.87e-2)" IL15 "IL-15, MGC9721" ENSG00000164136 "Interleukin 15" P40933 4 141636583-141733987 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "cDC: 149.7;Decidual stromal cells: 567.4;Endometrial stromal cells: 381.4;Epicardial cells: 147.8" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 118.2;endothelial cell: 54.5;leukocyte: 56.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004457, HPA037738" Approved Supported "Nucleoplasm,Nuclear speckles" "Secreted to blood" Interleukin NA NA 182000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 25: Non-specific - Transcription" "Cluster 59: Leukemia - T-cell receptor" "Cluster 82: Dendritic cells - Antigen presentation" 2 "Nucleoplasm, Nuclear speckles" "CAB004457: , HPA037738: " "unprognostic (3.12e-1)" "unprognostic (1.35e-1)" "unprognostic (1.47e-1)" "unprognostic (1.40e-1)" "unprognostic (2.61e-1)" "unprognostic (3.85e-2)" "potential prognostic unfavorable (8.28e-4)" "unprognostic (1.35e-1)" "unprognostic (3.14e-1)" "unprognostic (3.87e-3)" "unprognostic (1.60e-1)" "unprognostic (5.79e-2)" "unprognostic (3.23e-2)" "unprognostic (1.23e-2)" "potential prognostic favorable (5.90e-5)" "unprognostic (4.34e-2)" "unprognostic (1.11e-1)" "unprognostic (1.61e-1)" "unprognostic (3.19e-1)" "unprognostic (9.06e-2)" "unprognostic (1.52e-1)" "unprognostic (4.54e-2)" "potential prognostic unfavorable (4.70e-4)" "unprognostic (3.14e-1)" "unprognostic (3.92e-2)" "unprognostic (1.64e-1)" "unprognostic (5.96e-2)" "unprognostic (2.93e-2)" "unprognostic (2.99e-2)" "unprognostic (3.38e-2)" "unprognostic (2.62e-2)" IL15RA "CD215, IL-15RA" ENSG00000134470 "Interleukin 15 receptor subunit alpha" Q13261 10 5943639-5978187 "CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 53.0;Cholangiocytes: 63.3;Decidual stromal cells: 91.7;Endometrial stromal cells: 53.2;Fallopian secretory cells: 50.1;Fibroblasts: 69.8;Pancreatic acinar cells: 68.3;Pancreatic duct cells: 47.7;Sertoli cells: 55.4;Vascular endothelial cells: 58.2" "Group enriched" "Detected in many" 4 "central nervous system macrophage: 24.9;endothelial cell: 37.7;fibroblast: 30.5;leukocyte: 26.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Liver - Neutrophils, Pituitary gland - Endothelial cells, Prostate - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in all" "CAB026215, HPA036245" Approved Supported "Vesicles,Plasma membrane,Cytosol" "Secreted to blood" Receptor NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 13: Lung - Secretion" "Cluster 47: Endothelial cells - Vasculature" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 3 "Vesicles, Plasma membrane" Cytosol "CAB026215: , HPA036245: " "unprognostic (2.77e-1)" "unprognostic (4.63e-2)" "unprognostic (2.69e-3)" "unprognostic (9.21e-2)" "unprognostic (1.58e-2)" "unprognostic (1.23e-1)" "unprognostic (1.63e-2)" "unprognostic (1.89e-2)" "unprognostic (5.20e-2)" "unprognostic (2.27e-1)" "potential prognostic unfavorable (1.75e-5)" "unprognostic (4.15e-1)" "potential prognostic unfavorable (8.57e-6)" "validated prognostic unfavorable (7.22e-6)" "validated prognostic unfavorable (1.91e-4)" "unprognostic (5.30e-2)" "unprognostic (7.50e-3)" "unprognostic (3.62e-2)" "unprognostic (3.01e-2)" "unprognostic (1.16e-1)" "unprognostic (7.53e-2)" "potential prognostic unfavorable (1.80e-4)" "unprognostic (8.30e-2)" "unprognostic (2.61e-1)" "unprognostic (7.75e-2)" "unprognostic (3.28e-3)" "unprognostic (2.79e-2)" "unprognostic (2.66e-2)" "unprognostic (2.85e-2)" "unprognostic (1.11e-1)" "unprognostic (2.54e-2)" IL16 "FLJ16806, FLJ42735, HsT19289, IL-16, LCF, prIL-16" ENSG00000172349 "Interleukin 16" Q14005 15 81159575-81314058 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Chemotaxis, Host-virus interaction, Transcription, Transcription regulation" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 126.9" "Cell type enhanced" "Detected in many" "Adipocytes: 112.0;B-cells: 102.4;Brain excitatory neurons: 86.4;Choroid plexus epithelial cells: 242.1;Ependymal cells: 233.4;Epicardial cells: 116.0;Fibro-adipogenic progenitors: 141.9;Mesothelial cells: 192.2;Neutrophils: 109.3;Respiratory ciliated cells: 132.3" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 187.5;ependymal cell: 255.9;upper rhombic lip: 327.7" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "cerebellum: 116.9" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 25 "Leukemia: 33.0;lymphoma: 45.6;Myeloma: 44.7;skin cancer: 15.3" "Adipose visceral - Mesothelial cells, Adrenal gland - Fibroblasts, Breast - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Macrophages, Skin - Fibroblasts_2, Spleen - B-cells (Spleen)" "Group enriched" "Detected in all" 11 "cerebellum: 54.5;hippocampal formation: 27.1" "Region enriched" "Detected in many" 12 "cerebellum: 62.9" "CAB005247, HPA018467, HPA048861" Enhanced Approved "Nuclear speckles,Plasma membrane,Cytosol" "Secreted to blood" Interleukin NA NA 208000 5000 "Cluster 35: Neutrophils - Protein binding" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 35: Non-specific - DNA binding" "Cluster 55: Lymphoma - Immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 6 "Nuclear speckles" "Plasma membrane, Cytosol" "CAB005247: , HPA018467: , HPA048861: " "unprognostic (1.57e-2)" "unprognostic (1.30e-2)" "unprognostic (4.43e-2)" "unprognostic (1.15e-3)" "unprognostic (1.78e-1)" "unprognostic (2.10e-1)" "unprognostic (2.64e-1)" "unprognostic (4.71e-2)" "potential prognostic favorable (3.10e-4)" "unprognostic (1.09e-1)" "unprognostic (6.04e-3)" "unprognostic (2.20e-2)" "unprognostic (1.05e-1)" "unprognostic (1.07e-1)" "potential prognostic favorable (3.07e-4)" "potential prognostic favorable (1.04e-4)" "unprognostic (1.51e-2)" "unprognostic (6.25e-2)" "unprognostic (2.00e-1)" "unprognostic (1.10e-1)" "unprognostic (9.31e-2)" "unprognostic (7.64e-2)" "unprognostic (1.46e-1)" "unprognostic (1.53e-1)" "unprognostic (1.26e-1)" "unprognostic (9.87e-2)" "unprognostic (6.40e-2)" "unprognostic (1.64e-1)" "unprognostic (2.87e-2)" "unprognostic (1.53e-1)" "unprognostic (3.01e-2)" IL17A "CTLA8, IL-17, IL-17A, IL17" ENSG00000112115 "Interleukin 17A" Q16552 6 52186375-52190638 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Adaptive immunity, Immunity, Inflammatory response, Innate immunity" Cytokine "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.3" "Cell type enriched" "Detected in some" 7 "T-cells: 26.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA052258 Uncertain "Secreted to blood" Interleukin NA NA 9920 "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 20: Myeloma - Immune response" "Cluster 9: T-cells - Adaptive immunity: Regulation" 5 "HPA052258: " IL17B "IL-17B, IL-20, MGC138900, MGC138901, NIRF, ZCYTO7" ENSG00000127743 "Interleukin 17B" Q9UHF5 5 149371324-149404202 "Cancer-related genes, Predicted secreted proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 10.6" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 33.6;Hepatic stellate cells: 6.5;Late spermatids: 7.2;Peritubular myoid cells: 18.0;Salivary myoepithelial cells: 10.3;Schwann cells: 6.7;Smooth muscle cells: 9.6;Tuft cells: 11.5;Vascular smooth muscle cells: 18.1" "Cell type enhanced" "Detected in some" "vascular associated smooth muscle cell: 2.2" "Cancer enhanced" "Detected in some" "Breast Invasive Carcinoma (TCGA): 2.4" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 12 "basophil: 1.2" "Lineage enriched" "Detected in single" 12 "granulocytes: 1.2" "Cancer enriched" "Detected in some" 9 "Brain cancer: 11.6" "Adipose subcutaneous - Smooth muscle cells, Lung - Smooth muscle cells, Minor Salivary Gland - Smooth muscle cells, Prostate - Smooth muscle cells, Stomach - Fibroblasts, Testis - Sertoli cells, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA042441 Uncertain "Secreted to blood" Interleukin NA NA 75000 "Cluster 46: Basophils - Proteolysis" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 2: Neurons - Nucleosome" "Cluster 38: Non-specific - Transcription" "Cluster 62: Smooth muscle cells - Muscle contraction" 49 "HPA042441: " "potential prognostic favorable (3.34e-4)" "unprognostic (6.46e-2)" "unprognostic (3.38e-1)" "unprognostic (2.59e-1)" "unprognostic (3.85e-1)" IL17C "CX2, IL-17C, IL-21, MGC126884, MGC138401" ENSG00000124391 "Interleukin 17C" Q9P0M4 16 88638572-88640468 "Predicted secreted proteins" "Inflammatory response" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "endometrium 1: 1.9;urinary bladder: 1.5" "Cell type enhanced" "Detected in some" "Cholangiocytes: 4.0;Endometrial glandular cells: 2.2;Endometrial secretory cells: 2.3;Epididymal clear cells: 2.0;Esophageal apical cells: 1.7;Fallopian secretory cells: 6.6;Fallopian tube ciliated cells: 3.8;Gastric progenitor cells: 3.8;Goblet cells: 1.9;Pancreatic duct cells: 1.6" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Stomach Adenocarcinoma (TCGA): 2.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA065051 Supported "Secreted to blood" Interleukin NA NA 30500 "Cluster 75: Ovary - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 51: Secretory epithelial cells - Mixed function" "HPA065051: " "unprognostic (6.30e-2)" "unprognostic (4.76e-2)" "unprognostic (1.13e-1)" IL17D "FLJ30846, IL-17D, IL-27, IL27" ENSG00000172458 "Interleukin 17D" Q8TAD2 13 20702127-20723098 "Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 148.9;skeletal muscle: 122.7" "Cell type enhanced" "Detected in many" "Astrocytes: 96.1;Bergmann glia: 139.0;Late spermatids: 53.1;Müller glia: 22.3;Myonuclei: 84.8;Oligodendrocyte progenitor cells: 30.3" "Cell type enhanced" "Detected in many" "astrocyte: 114.6;Bergmann glia: 142.6" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 73.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Minor Salivary Gland - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Stomach - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" Interleukin NA NA 25000 "Cluster 78: Brain - Neuronal signaling" "Cluster 39: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 55: Myocytes - Oxidative muscle function" "unprognostic (1.11e-1)" "unprognostic (2.14e-2)" "unprognostic (3.50e-1)" "unprognostic (8.69e-3)" "unprognostic (1.03e-1)" "unprognostic (3.16e-2)" "unprognostic (7.89e-2)" "unprognostic (7.40e-3)" "unprognostic (3.46e-3)" "unprognostic (2.37e-2)" "unprognostic (1.51e-3)" "unprognostic (3.15e-3)" "unprognostic (2.74e-2)" "unprognostic (1.65e-2)" "unprognostic (1.65e-1)" "unprognostic (6.15e-2)" "unprognostic (2.55e-1)" "unprognostic (1.26e-1)" "unprognostic (7.32e-3)" "unprognostic (4.70e-2)" "unprognostic (1.97e-1)" "potential prognostic favorable (2.04e-4)" "unprognostic (1.60e-2)" "unprognostic (1.67e-1)" "unprognostic (1.49e-1)" "unprognostic (4.70e-2)" "unprognostic (4.08e-2)" "unprognostic (9.11e-2)" "unprognostic (1.37e-1)" "unprognostic (5.11e-2)" "unprognostic (2.50e-2)" IL17F "IL-17F, ML-1, ML1" ENSG00000112116 "Interleukin 17F" Q96PD4 6 52236681-52245689 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted secreted proteins" "Adaptive immunity, Immunity, Inflammatory response, Innate immunity" Cytokine "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 2.0" "Group enriched" "Detected in some" 5 "Innate lymphoid cells: 4.1;T-cells: 8.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 85 "lymphoma: 18.6" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" Interleukin NA NA 30000 "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 9: T-cells - Adaptive immunity: Regulation" 5 IL17RA "CD217, CDw217, hIL-17R, IL-17RA, IL17R" ENSG00000177663 "Interleukin 17 receptor A" Q96F46 22 17084954-17115693 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Host-virus interaction, Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 33.1" "Cell type enhanced" "Detected in many" "Microglia: 224.2;Monocyte progenitors: 390.3;monocytes: 208.7;Neutrophil progenitors: 579.4;Neutrophils: 1156.9" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 270.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 15.3" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Macrophages, Lung - Neutrophils_2, Skin - Macrophages, Spleen - Neutrophils_2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" CAB024996 Enhanced Approved Nucleoplasm,Cytosol "Secreted to blood" Receptor NA NA 20000 "Cluster 21: Neutrophils - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 36 "Nucleoplasm, Cytosol" "CAB024996: " "unprognostic (1.57e-1)" "unprognostic (8.79e-2)" "unprognostic (2.04e-2)" "unprognostic (1.36e-2)" "unprognostic (7.73e-2)" "unprognostic (4.10e-2)" "unprognostic (3.58e-1)" "unprognostic (1.14e-1)" "unprognostic (4.00e-2)" "unprognostic (2.42e-3)" "unprognostic (1.08e-3)" "unprognostic (5.60e-2)" "unprognostic (3.34e-1)" "unprognostic (6.79e-2)" "unprognostic (2.21e-1)" "unprognostic (3.47e-2)" "unprognostic (5.51e-2)" "unprognostic (1.05e-1)" "unprognostic (3.28e-2)" "unprognostic (1.47e-2)" "unprognostic (8.82e-2)" "unprognostic (1.12e-1)" "unprognostic (1.84e-3)" "unprognostic (1.44e-1)" "unprognostic (5.44e-2)" "unprognostic (5.61e-2)" "unprognostic (1.53e-1)" "unprognostic (1.26e-2)" "unprognostic (2.31e-2)" "unprognostic (6.37e-2)" "unprognostic (1.95e-2)" IL17RB "CRL4, EVI27, IL17BR, IL17RH1" ENSG00000056736 "Interleukin 17 receptor B" Q9NRM6 3 53846568-53865794 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 17.2;cervix: 16.9;kidney: 55.8;liver: 31.1" "Cell type enriched" "Detected in many" 9 "Tuft cells: 657.1" "Group enriched" "Detected in many" 4 "astrocyte: 53.1;Bergmann glia: 86.5;committed oligodendrocyte precursor: 79.2;oligodendrocyte precursor cell: 68.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Breast - Breast glandular cells, Kidney - Proximal tubular cells, Minor Salivary Gland - Minor salivary glandular cells, Stomach - Mitotic cells (Stomach), Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA005482 Enhanced Approved "Vesicles,Plasma membrane" "Intracellular and membrane" Receptor NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 76: Non-specific - Metabolism" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 18: Liver cancer - Metabolism" "Cluster 95: Tuft cells - Chemosensory signaling" 2 "Vesicles, Plasma membrane" "HPA005482: " "unprognostic (8.21e-3)" "unprognostic (3.24e-2)" "unprognostic (3.63e-1)" "unprognostic (1.89e-1)" "unprognostic (4.95e-3)" "unprognostic (3.54e-2)" "unprognostic (8.45e-3)" "unprognostic (6.06e-3)" "unprognostic (3.28e-2)" "unprognostic (1.49e-1)" "potential prognostic favorable (2.03e-6)" "unprognostic (2.56e-3)" "unprognostic (3.84e-3)" "unprognostic (9.72e-3)" "unprognostic (3.47e-1)" "unprognostic (2.13e-2)" "unprognostic (3.99e-2)" "unprognostic (1.36e-1)" "unprognostic (1.23e-2)" "unprognostic (6.15e-2)" "unprognostic (5.48e-2)" "unprognostic (2.77e-1)" "unprognostic (2.66e-1)" "unprognostic (6.28e-2)" "unprognostic (1.10e-2)" "unprognostic (1.94e-2)" "unprognostic (3.59e-1)" "unprognostic (8.28e-2)" "unprognostic (1.10e-1)" "unprognostic (3.78e-1)" "unprognostic (1.59e-1)" IL17RC IL17-RL ENSG00000163702 "Interleukin 17 receptor C" Q8NAC3 3 9917074-9933630 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Inflammatory response" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 29.3;Bergmann glia: 15.3;Choroid plexus epithelial cells: 11.2;Distal convoluted tubule cells: 11.4;Ependymal cells: 16.4;Loop of henle epithelial cells: 11.7;Microglia: 6.3;Oligodendrocyte progenitor cells: 13.9;Papillary tip epithelial cells: 7.3;Podocytes: 16.0;Proximal tubule cells: 23.8;Renal collecting duct intercalated cells: 9.9;Renal collecting duct principal cells: 10.7;Renal connecting tubule cells: 12.0" "Cell type enhanced" "Detected in many" "astrocyte: 37.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "HPA019885, CAB026255" Approved NA NA 8900 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 44: Non-specific - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" "CAB026255: , HPA019885: " "unprognostic (2.02e-1)" "unprognostic (6.89e-2)" "unprognostic (7.60e-2)" "unprognostic (8.00e-2)" "unprognostic (4.14e-2)" "unprognostic (4.30e-2)" "unprognostic (7.37e-2)" "unprognostic (2.25e-3)" "unprognostic (1.65e-1)" "unprognostic (2.60e-2)" "unprognostic (1.01e-3)" "unprognostic (2.29e-1)" "potential prognostic favorable (1.05e-4)" "unprognostic (1.53e-1)" "unprognostic (1.07e-1)" "unprognostic (1.44e-1)" "unprognostic (7.86e-3)" "unprognostic (2.34e-2)" "unprognostic (5.78e-1)" "unprognostic (8.17e-2)" "unprognostic (7.45e-2)" "unprognostic (1.01e-1)" "unprognostic (4.53e-2)" "unprognostic (7.15e-2)" "unprognostic (1.02e-2)" "unprognostic (6.25e-2)" "unprognostic (7.93e-3)" "unprognostic (2.09e-1)" "unprognostic (1.83e-1)" "unprognostic (5.88e-2)" "unprognostic (1.66e-1)" IL17RD "FLJ35755, IL-17RD, IL17RLM, SEF" ENSG00000144730 "Interleukin 17 receptor D" Q8NFM7 3 57089982-57170306 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 59.4;Choroid plexus epithelial cells: 107.7;Early spermatids: 32.2;Fibro-adipogenic progenitors: 57.2;Late primary spermatocytes: 31.7;Late spermatids: 42.4;Leydig cells: 41.0;Peritubular myoid cells: 45.1;Pituicytes/FSCs: 33.8;Pituitary stem cells: 51.3;Podocytes: 79.2;Proximal tubule cells: 37.7;Salivary myoepithelial cells: 37.8" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 85.5;endothelial cell: 76.8;fibroblast: 55.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 14.2" "Adipose subcutaneous - Adipose progenitor cells, Liver - Hepatic stellate cells, Lung - Fibroblasts_2, Minor Salivary Gland - Smooth muscle cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Prostate - Smooth muscle cells, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Testis - Early spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039577, HPA043550" Approved Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 8: Immune cells - Immune response" "Cluster 32: Non-specific - Cell proliferation" "Cluster 94: Gonadal somatic cells - Mixed function" 1 "Golgi apparatus" Nucleoplasm "HPA039577: , HPA043550: " "unprognostic (1.94e-1)" "unprognostic (1.18e-1)" "unprognostic (2.43e-1)" "unprognostic (2.17e-1)" "unprognostic (2.46e-1)" "unprognostic (5.44e-2)" "unprognostic (9.61e-3)" "unprognostic (1.07e-1)" "unprognostic (4.78e-2)" "unprognostic (1.82e-2)" "validated prognostic favorable (7.32e-9)" "validated prognostic favorable (2.17e-5)" "potential prognostic favorable (3.95e-5)" "unprognostic (1.85e-1)" "potential prognostic unfavorable (2.88e-4)" "unprognostic (1.45e-1)" "unprognostic (1.30e-1)" "unprognostic (2.80e-2)" "unprognostic (2.81e-1)" "unprognostic (6.24e-2)" "unprognostic (7.24e-2)" "unprognostic (3.44e-2)" "unprognostic (1.51e-1)" "unprognostic (2.07e-1)" "unprognostic (2.51e-1)" "unprognostic (4.39e-1)" "unprognostic (2.12e-1)" "unprognostic (5.68e-2)" "unprognostic (1.01e-2)" IL17RE FLJ23658 ENSG00000163701 "Interleukin 17 receptor E" Q8NFR9 3 9902612-9916402 "Predicted intracellular proteins, Predicted membrane proteins" "Inflammatory response" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 19.6;skin 1: 29.6" "Cell type enhanced" "Detected in many" "Colonocytes: 88.2;Enteric stem cells: 48.6;Enteric transient amplifying cells: 50.7;Enterocytes: 103.1;Foveolar cells: 83.8;Goblet cells: 96.8;Paneth cells: 58.0" "Cell type enhanced" "Detected in all" "eccentric medium spiny neuron: 31.6" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "basal ganglia: 2.9;cerebellum: 4.0;hypothalamus: 1.3;medulla oblongata: 1.4;pons: 4.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast myoepithelial cells, Liver - Hepatocytes, Lung - Alveolar cells type 1, Spleen - Fibroblasts_1, Stomach - Gastric mucous cells" "Region enhanced" "Detected in single" "cerebellum: 1.5" HPA019011 Uncertain "Intracellular and membrane" Receptor NA NA "Cluster 77: Intestine - Digestion" "Cluster 37: Neurons - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 70: Intestinal goblet cells - Mucin production" "HPA019011: " "unprognostic (1.12e-1)" "unprognostic (3.37e-3)" "unprognostic (2.67e-2)" "unprognostic (2.19e-3)" "unprognostic (4.46e-2)" "unprognostic (5.85e-2)" "unprognostic (1.13e-2)" "unprognostic (4.18e-1)" "potential prognostic favorable (4.34e-5)" "unprognostic (1.39e-1)" "unprognostic (5.14e-2)" "unprognostic (3.27e-1)" "unprognostic (2.32e-3)" "unprognostic (4.09e-2)" "unprognostic (2.05e-1)" "unprognostic (4.96e-2)" "unprognostic (2.37e-1)" "unprognostic (8.11e-2)" "unprognostic (3.88e-1)" "unprognostic (3.20e-3)" "unprognostic (7.24e-3)" "unprognostic (3.23e-1)" "unprognostic (3.29e-2)" "unprognostic (5.60e-2)" "unprognostic (3.92e-1)" "unprognostic (1.73e-1)" "unprognostic (1.82e-1)" "unprognostic (1.46e-1)" "unprognostic (4.43e-2)" IL17REL FLJ41993 ENSG00000188263 "Interleukin 17 receptor E like" 22 49991811-50012765 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "lymphoid tissue: 4.0;stomach 1: 1.7" "Cell type enhanced" "Detected in some" "Endometrial glandular cells: 13.6;Endometrial luminal cells: 22.9;Endometrial secretory cells: 13.9;Epicardial cells: 34.1;Foveolar cells: 23.0;Goblet cells: 5.9;Oocytes: 4.6" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Stomach Adenocarcinoma (TCGA): 1.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" HPA045546 Supported NA NA "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 7: Liver cancer - Metabolism" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" "HPA045546: " "unprognostic (5.94e-2)" "unprognostic (7.21e-2)" "unprognostic (2.03e-1)" "unprognostic (1.59e-1)" "unprognostic (9.93e-2)" IL18 "IGIF, IL-18, IL-1g, IL1F4" ENSG00000150782 "Interleukin 18" Q14116 11 112143253-112164096 "Cancer-related genes, Candidate cardiovascular disease genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 117.0;skin 1: 140.9" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 318.3;Esophageal apical cells: 2424.9;Kupffer cells: 460.2;Ocular epithelial cells: 815.7;Renal collecting duct intercalated cells: 638.3" "Cell type enriched" "Detected in all" 8 "central nervous system macrophage: 338.5" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 141.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 25.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adipose visceral - Mesothelial cells, Adrenal gland - Macrophages, Liver - Kupffer cells, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003980, CAB007772" Enhanced Approved "Nucleoplasm,Golgi apparatus,Cytosol" "Secreted to blood" Interleukin NA Yes 196000 21000 "Cluster 29: Non-specific - Unknown function" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 84: Apical squamous epithelium - Cornification" 3 "Nucleoplasm, Golgi apparatus" Cytosol "CAB007772: , HPA003980: " "unprognostic (2.17e-2)" "unprognostic (2.04e-3)" "unprognostic (2.37e-2)" "unprognostic (1.22e-1)" "unprognostic (5.40e-3)" "unprognostic (2.32e-2)" "unprognostic (4.29e-2)" "unprognostic (8.14e-2)" "unprognostic (3.34e-2)" "unprognostic (2.19e-1)" "unprognostic (1.91e-2)" "unprognostic (3.01e-2)" "unprognostic (4.25e-1)" "unprognostic (7.12e-2)" "unprognostic (8.77e-2)" "unprognostic (1.46e-2)" "unprognostic (4.78e-2)" "unprognostic (1.80e-1)" "unprognostic (2.28e-3)" "unprognostic (1.71e-1)" "unprognostic (7.60e-2)" "validated prognostic unfavorable (4.43e-4)" "validated prognostic unfavorable (1.19e-4)" "unprognostic (2.40e-1)" "unprognostic (1.56e-1)" "unprognostic (1.18e-1)" "unprognostic (3.34e-1)" "unprognostic (1.94e-1)" "unprognostic (8.75e-2)" "unprognostic (2.42e-2)" "unprognostic (4.82e-1)" IL18BP IL18BPa ENSG00000137496 "Interleukin 18 binding protein" O95998 11 71998613-72007315 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 44.3" "Cell type enhanced" "Detected in many" "Adipocytes: 20.0;Cardiomyocytes: 63.2;Epicardial cells: 38.7;Kupffer cells: 17.4;Macrophages: 21.5;Vascular endothelial cells: 15.3" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 10.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025980, HPA041061" Enhanced Approved "Endoplasmic reticulum" "Secreted to blood" "No annotated function" NA NA 3070000 2900000 "Cluster 25: Non-specific - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "Endoplasmic reticulum" "CAB025980: , HPA041061: " "unprognostic (2.80e-2)" "unprognostic (5.77e-3)" "unprognostic (3.08e-2)" "unprognostic (1.03e-3)" "unprognostic (3.75e-2)" "unprognostic (3.39e-1)" "unprognostic (8.63e-2)" "unprognostic (9.31e-2)" "unprognostic (3.60e-2)" "unprognostic (3.32e-1)" "unprognostic (3.27e-2)" "unprognostic (3.27e-1)" "unprognostic (2.48e-1)" "unprognostic (1.80e-1)" "unprognostic (1.16e-2)" "unprognostic (1.48e-1)" "unprognostic (2.01e-1)" "unprognostic (1.99e-1)" "unprognostic (4.14e-1)" "unprognostic (9.73e-3)" "unprognostic (2.24e-2)" "unprognostic (1.34e-1)" "potential prognostic unfavorable (2.45e-4)" "unprognostic (1.28e-1)" "unprognostic (1.01e-1)" "unprognostic (1.01e-3)" "unprognostic (8.59e-3)" "unprognostic (1.64e-1)" "unprognostic (1.47e-1)" "unprognostic (5.49e-2)" "unprognostic (1.37e-1)" IL18R1 "CD218a, IL-1Rrp, IL1RRP" ENSG00000115604 "Interleukin 18 receptor 1" Q13478 2 102311529-102398777 "CD markers, Enzymes, Plasma proteins, Predicted membrane proteins" "Inflammatory response" "Hydrolase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 11.3" "Group enriched" "Detected in many" 8 "Mast cells: 1307.9;Neutrophils: 3312.5" "Group enriched" "Detected in some" 6 "endothelial cell: 71.4;leukocyte: 89.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 45.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Liver - Neutrophils, Spleen - Neutrophils_2, Testis - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA007615 Approved Approved Mitochondria Yes No "Cluster 15: NK-cells - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 55: Lymphoma - Immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 1 Mitochondria "HPA007615: " "potential prognostic favorable (1.88e-4)" "unprognostic (3.53e-1)" "unprognostic (6.53e-3)" "unprognostic (4.07e-2)" "potential prognostic favorable (7.74e-7)" "unprognostic (5.14e-2)" "unprognostic (7.94e-3)" "unprognostic (6.30e-2)" "unprognostic (2.99e-1)" "unprognostic (6.70e-2)" "unprognostic (1.17e-1)" "unprognostic (6.85e-3)" "unprognostic (3.33e-2)" "unprognostic (2.12e-1)" "unprognostic (3.25e-2)" "unprognostic (5.97e-3)" "unprognostic (1.30e-1)" "unprognostic (2.74e-2)" IL18RAP "AcPL, CD218b" ENSG00000115607 "Interleukin 18 receptor accessory protein" O95256 2 102418689-102452565 "CD markers, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Inflammatory response" "Hydrolase, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "bone marrow: 101.8" "Group enriched" "Detected in some" 6 "Neutrophil progenitors: 294.5;Neutrophils: 912.1" "Cell type enriched" "Detected in single" 135 "leukocyte: 86.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "NK-cell: 120.7" "Group enriched" "Detected in many" 104 "granulocytes: 69.6;NK-cells: 120.7;T-cells: 67.5" "Group enriched" "Detected in some" 20 "Leukemia: 2.6;lymphoma: 1.6" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Lung - Neutrophils_2, Skeletal muscle - Neutrophils, Spleen - Neutrophils_2, Thyroid gland - Neutrophils" "Not detected" "Not detected" "Not detected" "Not detected" CAB025270 Enhanced NA NA "Cluster 24: Non-specific - Transcription" "Cluster 15: Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 1 "CAB025270: " "unprognostic (8.95e-2)" "unprognostic (7.15e-2)" "unprognostic (4.93e-1)" "unprognostic (3.04e-1)" "unprognostic (4.01e-3)" "unprognostic (3.12e-3)" "unprognostic (7.88e-2)" "unprognostic (3.28e-3)" "unprognostic (9.31e-2)" "unprognostic (3.77e-2)" "unprognostic (2.31e-2)" "unprognostic (9.19e-2)" "unprognostic (1.10e-1)" IL19 "IL-10C, IL-19, MDA1, NG.1, ZMDA1" ENSG00000142224 "Interleukin 19" Q9UHD0 1 206770764-206842981 "Predicted secreted proteins" Apoptosis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "cervix: 18.7;salivary gland: 6.5" "Cell type enhanced" "Detected in many" "Breast lactating cells: 29.8;Breast secretory cells: 11.4;Conjunctival goblet cells: 12.6;Early spermatids: 16.2;Endometrial luminal cells: 23.7;Endometrial secretory cells: 24.6;monocytes: 19.3;pDCs: 17.4;Salivary basal cells: 17.2;Salivary duct cells: 45.1;Tuft cells: 11.5" "Cell type enhanced" "Detected in single" "central nervous system macrophage: 2.5" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 4.4;Uterine Corpus Endometrial Carcinoma (TCGA): 9.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lymphoma: 1.1" "Minor Salivary Gland - Minor salivary gland ductal cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" Interleukin NA NA 172000 "Cluster 82: Salivary gland - Secretion" "Cluster 48: Non-specific - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" "unprognostic (3.02e-2)" "unprognostic (1.58e-2)" "unprognostic (2.03e-1)" "unprognostic (1.63e-3)" "unprognostic (4.73e-2)" "unprognostic (1.02e-1)" "unprognostic (9.60e-2)" "unprognostic (1.65e-2)" IL1A "IL-1A, IL1, IL1-ALPHA, IL1F1" ENSG00000115008 "Interleukin 1 alpha" P01583 2 112773925-112784493 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Inflammatory response" "Cytokine, Mitogen, Pyrogen" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 13.5;testis: 9.7;urinary bladder: 24.1" "Cell type enhanced" "Detected in some" "Epididymal basal cells: 227.6;Esophageal apical cells: 77.2;Macrophages: 47.7;monocytes: 154.7;Neutrophils: 76.3;Ocular epithelial cells: 298.9;Urothelial cells: 356.5" "Cell type enriched" "Detected in some" 19 "central nervous system macrophage: 30.2" "Group enriched" "Detected in many" 10 "Bladder Urothelial Carcinoma (TCGA): 22.9;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 12.4;Head and Neck Squamous Cell Carcinoma (TCGA): 32.7;Lung Squamous Cell Carcinoma (TCGA): 11.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 98.6;head and neck cancer: 136.3" "Spleen - B-cells (Spleen), Testis - Sertoli cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA075911, CAB080496" Supported Cytosol "Secreted to blood" Interleukin NA NA 10800 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 10 Cytosol "CAB080496: , HPA075911: " "unprognostic (4.81e-3)" "unprognostic (2.06e-3)" "unprognostic (3.46e-2)" "unprognostic (1.67e-3)" "unprognostic (1.17e-1)" "unprognostic (1.28e-1)" "unprognostic (6.92e-3)" "unprognostic (4.04e-3)" "unprognostic (4.51e-3)" "unprognostic (2.69e-3)" "potential prognostic unfavorable (4.60e-4)" "unprognostic (9.90e-3)" "unprognostic (8.92e-3)" "unprognostic (1.02e-1)" "unprognostic (1.25e-1)" "potential prognostic unfavorable (2.58e-4)" IL1B "IL-1B, IL1-BETA, IL1F2" ENSG00000125538 "Interleukin 1 beta" P01584 2 112829751-112836816 "Cancer-related genes, Candidate cardiovascular disease genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Inflammatory response" "Cytokine, Mitogen, Pyrogen" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 190.0;urinary bladder: 117.2" "Cell type enhanced" "Detected in many" "cDC: 1016.3;Macrophages: 1016.8;monocytes: 4378.2;Neutrophils: 2506.4" "Group enriched" "Detected in some" 39 "central nervous system macrophage: 27.1;leukocyte: 6.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "neutrophil: 94.5" "Lineage enriched" "Detected in many" 5 "granulocytes: 94.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 177.9;Sarcoma: 319.5" "Kidney - Macrophages, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to blood" Interleukin NA NA 2330 "Cluster 28: Neutrophils - Unknown function" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 7 "unprognostic (2.08e-1)" "unprognostic (2.39e-2)" "unprognostic (9.31e-2)" "potential prognostic unfavorable (5.36e-5)" "unprognostic (5.84e-3)" "unprognostic (6.84e-2)" "unprognostic (4.71e-2)" "unprognostic (6.12e-2)" "unprognostic (6.92e-2)" "unprognostic (1.96e-1)" "unprognostic (1.36e-1)" "unprognostic (3.01e-1)" "unprognostic (3.34e-1)" "unprognostic (9.36e-3)" "unprognostic (2.00e-1)" "unprognostic (2.18e-1)" "unprognostic (3.93e-3)" "unprognostic (1.16e-3)" "unprognostic (3.19e-2)" "unprognostic (2.24e-2)" "unprognostic (2.24e-1)" "unprognostic (5.50e-2)" "unprognostic (2.52e-2)" "unprognostic (3.66e-2)" "unprognostic (2.11e-1)" "unprognostic (2.33e-2)" "unprognostic (3.61e-1)" "unprognostic (2.66e-2)" "unprognostic (1.79e-1)" "unprognostic (1.37e-1)" "unprognostic (2.09e-1)" IL1F10 "FKSG75, IL-1F10, IL-1HY2, IL1-theta, MGC11983, MGC119832, MGC119833" ENSG00000136697 "Interleukin 1 family member 10" Q8WWZ1 2 113067970-113075843 "Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "skin 1: 12.2" "Cell type enriched" "Detected in single" 5 "Esophageal apical cells: 2.4" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "Head and Neck Squamous Cell Carcinoma (TCGA): 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" Interleukin NA NA 222000 "Cluster 9: Skin - Hair follicle development" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 1 "unprognostic (5.89e-2)" IL1R1 "CD121A, D2S1473, IL1R, IL1RA" ENSG00000115594 "Interleukin 1 receptor type 1" P14778 2 102064544-102179874 "Cancer-related genes, CD markers, Enzymes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Inflammatory response" "Hydrolase, Receptor" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "Neutrophils: 5197.1" "Cell type enhanced" "Detected in many" "endothelial cell: 312.2;fibroblast: 120.4;pericyte: 102.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Pituitary gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001237, HPA005823, CAB007779, HPA029560" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" "Secreted to blood" Receptor NA NA 330000 "Cluster 35: Neutrophils - Protein binding" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 12: Non-specific - Vasculature" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 24: Neutrophils - Innate immunity signal integration" 13 "Nucleoplasm, Vesicles" "Plasma membrane, Cytosol" "CAB007779: , HPA001237: , HPA005823: , HPA029560: " "unprognostic (2.65e-2)" "unprognostic (4.67e-3)" "unprognostic (2.16e-2)" "unprognostic (6.26e-2)" "unprognostic (3.31e-1)" "unprognostic (2.24e-2)" "potential prognostic unfavorable (8.74e-4)" "unprognostic (2.42e-1)" "unprognostic (7.75e-2)" "unprognostic (1.04e-2)" "unprognostic (2.88e-1)" "unprognostic (1.41e-2)" "unprognostic (8.22e-3)" "unprognostic (1.69e-1)" "unprognostic (6.67e-2)" "unprognostic (1.07e-1)" "unprognostic (5.53e-2)" "unprognostic (1.40e-1)" "unprognostic (5.45e-2)" "unprognostic (2.04e-1)" "unprognostic (5.34e-3)" "unprognostic (2.02e-2)" "unprognostic (2.79e-1)" "unprognostic (4.86e-2)" "unprognostic (5.11e-2)" "unprognostic (9.99e-2)" "unprognostic (3.78e-2)" "unprognostic (9.79e-3)" "unprognostic (7.90e-2)" "unprognostic (6.69e-2)" "unprognostic (2.78e-1)" IL1R2 "CD121b, IL1RB" ENSG00000115590 "Interleukin 1 receptor type 2" P27930 2 101991960-102028544 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 91.9" "Cell type enriched" "Detected in many" 4 "Neutrophils: 17940.8" "Cell type enriched" "Detected in single" 20 "leukocyte: 7.4" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 45.4" "Region enhanced" "Detected in many" "cerebral cortex: 14.5" "Immune cell enriched" "Detected in some" 26 "neutrophil: 378.7" "Lineage enriched" "Detected in many" 26 "granulocytes: 378.7" "Cancer enhanced" "Detected in many" "lymphoma: 66.7" "Adipose visceral - Neutrophils, Lung - Neutrophils_2, Pituitary gland - Neutrophils, Prostate - Macrophages, Skeletal muscle - Neutrophils, Spleen - Neutrophils_2" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA027597, HPA027598" Uncertain "Secreted to blood" Receptor NA NA 7130000 11000000 "Cluster 4: Neutrophils - Degranulation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 12: Non-specific - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 20 "HPA027597: , HPA027598: " "unprognostic (1.57e-1)" "unprognostic (1.13e-1)" "unprognostic (2.40e-2)" "unprognostic (1.58e-2)" "unprognostic (8.58e-2)" "unprognostic (1.46e-1)" "unprognostic (3.33e-3)" "unprognostic (3.84e-2)" "unprognostic (2.27e-1)" "unprognostic (1.86e-1)" "potential prognostic unfavorable (3.74e-4)" "unprognostic (2.46e-2)" "potential prognostic unfavorable (8.46e-4)" "unprognostic (3.59e-2)" "potential prognostic unfavorable (2.25e-5)" "potential prognostic unfavorable (8.06e-5)" "unprognostic (5.20e-2)" "unprognostic (9.88e-2)" "unprognostic (2.02e-1)" "unprognostic (1.27e-1)" "unprognostic (3.84e-2)" "unprognostic (1.85e-3)" "unprognostic (8.14e-2)" "unprognostic (7.23e-2)" "unprognostic (7.49e-2)" "unprognostic (1.70e-1)" "unprognostic (5.66e-2)" "unprognostic (1.77e-1)" "unprognostic (3.13e-1)" "unprognostic (6.14e-3)" IL1RAP "C3orf13, IL-1RAcP, IL1R3" ENSG00000196083 "Interleukin 1 receptor accessory protein" Q9NPH3 3 190514051-190659750 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Hydrolase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "liver: 210.8" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 483.3;Hepatocytes: 512.1;monocytes: 238.0;Neutrophil progenitors: 246.6;Neutrophils: 1802.6;Oligodendrocyte progenitor cells: 287.1;Schwann cells: 232.0" "Cell type enhanced" "Detected in all" "oligodendrocyte precursor cell: 318.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "eosinophil: 23.9;neutrophil: 95.8" "Lineage enriched" "Detected in many" 15 "granulocytes: 95.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035293 Uncertain Approved Vesicles,Cytosol "Secreted to blood" Receptor NA NA 130000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 51: Neurons - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 24: Neutrophils - Innate immunity signal integration" 11 "Vesicles, Cytosol" "HPA035293: " "potential prognostic unfavorable (6.29e-5)" "unprognostic (2.07e-1)" "unprognostic (2.84e-1)" "unprognostic (1.36e-1)" "unprognostic (8.37e-2)" "unprognostic (2.86e-1)" "unprognostic (7.99e-2)" "potential prognostic unfavorable (2.17e-4)" "unprognostic (3.37e-2)" "unprognostic (3.36e-3)" "unprognostic (1.66e-3)" "unprognostic (5.63e-2)" "unprognostic (1.62e-3)" "unprognostic (2.69e-2)" "unprognostic (8.57e-3)" "unprognostic (4.73e-2)" "potential prognostic unfavorable (5.41e-4)" "unprognostic (3.19e-1)" "unprognostic (2.23e-1)" "unprognostic (1.60e-1)" "unprognostic (3.84e-3)" "potential prognostic unfavorable (4.45e-4)" "unprognostic (4.34e-3)" "unprognostic (5.42e-2)" "unprognostic (2.04e-1)" "unprognostic (9.44e-2)" "unprognostic (1.28e-1)" "unprognostic (2.82e-3)" "unprognostic (2.30e-1)" "unprognostic (1.56e-1)" "unprognostic (2.56e-3)" IL1RAPL1 "IL1R8, IL1RAPL, MRX10, MRX21, MRX34, OPHN4, TIGIRR-2" ENSG00000169306 "Interleukin 1 receptor accessory protein like 1" Q9NZN1 X 28587446-29956718 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Hydrolase, Receptor" "Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 5 "brain: 2.9" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 1456.8;Brain inhibitory neurons: 2265.1;Cardiomyocytes: 1773.1;Lactotrophs: 684.7;Oligodendrocyte progenitor cells: 2678.4;Oligodendrocytes: 7726.1;Retinal amacrine cells: 993.9;Schwann cells: 834.9" "Cell type enhanced" "Detected in all" "oligodendrocyte: 9661.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "skin cancer: 7.7" "Colon - Enteric glia cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 80: Oligodendrocytes - Myelination" 2 "potential prognostic favorable (5.03e-6)" IL1RAPL2 "IL-1R9, IL1R9, IL1RAPL-2, TIGIRR-1" ENSG00000189108 "Interleukin 1 receptor accessory protein like 2" Q9NP60 X 104566199-105767829 "Enzymes, Predicted membrane proteins" "Hydrolase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "adrenal gland: 1.3" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 182.7;Breast myoepithelial cells: 198.9;Cytotrophoblasts: 243.1;Distal convoluted tubule cells: 402.5;Leydig cells: 646.0;Other brain neurons: 192.8;Papillary tip epithelial cells: 425.7;Prostatic hillock cells: 202.6;Renal collecting duct principal cells: 492.7;Retinal ganglion cells: 266.5;Schwann cells: 172.6;Syncytiotrophoblasts: 153.2;Urothelial cells: 173.6" "Cell type enhanced" "Detected in all" "deep-layer intratelencephalic: 594.7;lower rhombic lip: 438.2;splatter: 702.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Sarcoma: 1.0" "Adrenal gland - Adrenal medulla cells, Breast - Breast myoepithelial cells, Colon - Enteric glia cells, Liver - Hepatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA077129 Approved "Plasma membrane" NA NA "Cluster 61: Non-specific - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 109: Neurons - Neuronal signaling" "Plasma membrane" "HPA077129: " "unprognostic (2.36e-2)" IL1RL1 "DER4, FIT-1, IL33R, ST2, ST2L, ST2V, T1" ENSG00000115602 "Interleukin 1 receptor like 1" Q01638 2 102311502-102352037 "Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "choroid plexus: 58.2;kidney: 116.5;lung: 158.6;placenta: 187.6" "Group enriched" "Detected in some" 5 "Epididymal basal cells: 119.9;Mast cells: 329.3" "Cell type enhanced" "Detected in single" "endothelial cell: 1.1" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 17.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 64 "basophil: 38.4;eosinophil: 29.4" "Lineage enriched" "Detected in single" 73 "granulocytes: 38.4" "Cancer enhanced" "Detected in many" "Esophageal cancer: 24.0;pancreatic cancer: 13.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA007406, HPA007917" Uncertain Supported "Plasma membrane,Focal adhesion sites,Cytosol" "Secreted to blood" Receptor NA NA 19100000 6900000 "Cluster 41: Basophils - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 49: HMC-1 - Innate immune response" "Cluster 58: Mast cells - Allergic inflammatory responses" 2 "Plasma membrane" "Focal adhesion sites, Cytosol" "HPA007406: , HPA007917: " "unprognostic (7.84e-2)" "unprognostic (4.38e-2)" "unprognostic (7.39e-3)" "unprognostic (1.09e-2)" "potential prognostic favorable (1.56e-5)" "unprognostic (5.69e-3)" "unprognostic (1.45e-1)" "unprognostic (5.93e-2)" "unprognostic (4.68e-1)" "unprognostic (5.90e-2)" "unprognostic (1.55e-1)" "unprognostic (1.04e-1)" "unprognostic (2.05e-2)" "potential prognostic favorable (1.43e-4)" "unprognostic (1.13e-2)" "unprognostic (7.56e-2)" IL1RL2 "IL-36R, IL1R-rp2, IL1RRP2" ENSG00000115598 "Interleukin 1 receptor like 2" Q9HB29 2 102187006-102240002 "Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" "Hydrolase, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 11.6" "Cell type enhanced" "Detected in many" "cDC: 39.6;Distal convoluted tubule cells: 39.8;Endometrial glandular cells: 92.2;Endometrial luminal cells: 92.6;Endometrial secretory cells: 52.8;Epididymal basal cells: 71.9;Esophageal apical cells: 89.6;Esophageal suprabasal cells: 41.6;Neutrophils: 39.5;Ocular epithelial cells: 52.4;Suprabasal keratinocytes: 59.3;Urothelial cells: 42.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 4.0" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in single" "Region enhanced" "Detected in single" "hippocampal formation: 1.5" NA NA "Cluster 58: Skin - Keratinization" "Cluster 24: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 51: Secretory epithelial cells - Mixed function" 1 "unprognostic (1.34e-1)" "unprognostic (4.13e-2)" "unprognostic (2.48e-1)" "unprognostic (1.81e-1)" "unprognostic (1.25e-1)" "unprognostic (7.83e-3)" "unprognostic (1.05e-1)" "unprognostic (5.48e-2)" "potential prognostic favorable (1.43e-4)" "unprognostic (2.55e-2)" "unprognostic (6.34e-2)" "unprognostic (4.63e-3)" "unprognostic (1.65e-2)" "unprognostic (2.80e-2)" "unprognostic (2.13e-3)" "potential prognostic favorable (6.53e-4)" "unprognostic (6.30e-2)" "unprognostic (2.56e-2)" "unprognostic (1.40e-1)" "unprognostic (3.52e-3)" "unprognostic (1.28e-1)" "unprognostic (1.93e-2)" "unprognostic (1.28e-2)" "unprognostic (4.33e-2)" "unprognostic (1.45e-2)" IL1RN "ICIL-1RA, IL-1RN, IL1F3, IL1RA, IRAP, MGC10430" ENSG00000136689 "Interleukin 1 receptor antagonist" P18510 2 113099315-113134016 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "esophagus: 1886.8" "Cell type enriched" "Detected in many" 5 "Esophageal apical cells: 19453.8" "Cell type enriched" "Detected in single" 4 "leukocyte: 2.0" "Cancer enhanced" "Detected in all" "Head and Neck Squamous Cell Carcinoma (TCGA): 238.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "classical monocyte: 69.8;myeloid DC: 66.9;neutrophil: 257.2" "Group enriched" "Detected in many" 738 "dendritic cells: 66.9;granulocytes: 257.2;monocytes: 69.8" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 164.8" "Heart muscle - Neutrophils, Prostate - Urothelial cells, Skin - Keratinocyte (other), Spleen - Neutrophils_2, Testis - Late spermatids" "Not detected" "Not detected" "HPA001482, CAB009633, CAB080340" Enhanced Approved Nucleoplasm,Centrosome,Cytosol "Secreted to blood" "No annotated function" NA NA 291000 1800000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 84: Apical squamous epithelium - Cornification" 5 "Nucleoplasm, Cytosol" Centrosome "CAB009633: , CAB080340: , HPA001482: " "potential prognostic favorable (5.71e-4)" "unprognostic (4.41e-2)" "unprognostic (1.71e-1)" "unprognostic (3.00e-2)" "unprognostic (2.90e-1)" "unprognostic (1.16e-1)" "unprognostic (9.23e-2)" "unprognostic (1.12e-1)" "unprognostic (1.88e-1)" "unprognostic (1.40e-1)" "unprognostic (2.10e-3)" "unprognostic (2.08e-1)" "unprognostic (6.75e-3)" "unprognostic (1.44e-2)" "unprognostic (3.01e-2)" "unprognostic (9.31e-2)" "potential prognostic unfavorable (3.17e-4)" "unprognostic (2.89e-1)" "unprognostic (1.42e-2)" "unprognostic (2.68e-2)" "unprognostic (1.34e-2)" "potential prognostic unfavorable (5.71e-4)" "unprognostic (2.06e-1)" "unprognostic (9.35e-3)" "unprognostic (4.61e-2)" "unprognostic (1.01e-1)" "unprognostic (3.84e-2)" "unprognostic (2.47e-1)" "unprognostic (4.34e-3)" "unprognostic (5.52e-2)" "unprognostic (4.65e-2)" IL2 "IL-2, TCGF" ENSG00000109471 "Interleukin 2" P60568 4 122451470-122456725 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Cytokine, Growth factor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Innate lymphoid cells: 11.6;T-cells: 17.9" "Cell type enriched" "Detected in single" 58 "leukocyte: 5.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - T-cells, Breast - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" CAB010310 Uncertain "Secreted to blood" Interleukin NA NA 20300 "Cluster 59: Leukemia - T-cell receptor" "Cluster 20: Non-specific - Transcription regulation" 3 "CAB010310: " IL20 "IL-20, IL10D, ZCYTO10" ENSG00000162891 "Interleukin 20" Q9NYY1 1 206865623-206869223 "Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 1.6;skin 1: 1.2" "Group enriched" "Detected in some" 4 "Basal keratinocytes: 50.5;Breast hormone-responsive cells: 17.8;Epicardial cells: 47.8;Granulosa cells: 21.9;Salivary basal cells: 15.9" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Breast Invasive Carcinoma (TCGA): 7.3;Head and Neck Squamous Cell Carcinoma (TCGA): 2.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 13 "breast cancer: 6.4" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Minor Salivary Gland - Minor salivary glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB025802, HPA067147" Uncertain Approved "Endoplasmic reticulum,Vesicles" "Secreted to blood" Interleukin NA NA 109000 "Cluster 37: Skin - Keratinization" "Cluster 27: Breast cancer - Unknown function" "Cluster 26: Keratinocytes - Keratinization" 5 Vesicles "Endoplasmic reticulum" "CAB025802: , HPA067147: " "unprognostic (5.06e-2)" "unprognostic (1.44e-1)" "unprognostic (9.00e-2)" "unprognostic (8.02e-3)" IL20RA "IL-20R1, ZCYTOR7" ENSG00000016402 "Interleukin 20 receptor subunit alpha" Q9UHF4 6 136999971-137045180 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 24.8;skin 1: 35.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 89.7;Breast hormone-responsive cells: 85.1;Breast lactating cells: 81.2;Endometrial ciliated cells: 134.1;Endometrial glandular cells: 82.5;Endometrial luminal cells: 91.8;Fallopian tube ciliated cells: 107.1;Neuroendocrine cells: 87.1;Respiratory ciliated cells: 111.6" "Cell type enhanced" "Detected in many" "astrocyte: 21.3;choroid plexus epithelial cell: 22.5;ependymal cell: 41.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 17.8" "Breast - Breast glandular cells, Breast - Breast glandular cells, Lung - Alveolar cells type 2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB024990, HPA042281" Approved Approved Cytosol NA NA "Cluster 58: Skin - Keratinization" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 1 Cytosol "CAB024990: , HPA042281: " "unprognostic (2.95e-2)" "unprognostic (6.78e-2)" "unprognostic (1.85e-2)" "unprognostic (1.68e-3)" "unprognostic (1.90e-1)" "unprognostic (1.88e-1)" "unprognostic (1.34e-2)" "potential prognostic unfavorable (6.57e-5)" "potential prognostic favorable (1.91e-4)" "potential prognostic favorable (1.02e-4)" "unprognostic (1.70e-2)" "unprognostic (9.57e-2)" "unprognostic (1.86e-2)" "unprognostic (1.02e-1)" "unprognostic (3.17e-2)" "unprognostic (1.03e-1)" "unprognostic (3.62e-2)" "unprognostic (2.26e-3)" "unprognostic (7.86e-3)" "unprognostic (6.96e-3)" "unprognostic (1.44e-1)" "unprognostic (1.72e-3)" "unprognostic (9.60e-2)" "unprognostic (1.80e-2)" "unprognostic (5.49e-3)" IL20RB "DIRS1, FNDC6, IL-20R2, MGC34923" ENSG00000174564 "Interleukin 20 receptor subunit beta" Q6UXL0 3 136946230-137011085 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "cervix: 58.4;esophagus: 121.1;skin 1: 165.8;vagina: 74.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 102.4;Early spermatids: 60.7;Esophageal apical cells: 547.3;Esophageal basal cells: 174.1;Esophageal suprabasal cells: 273.2;Ocular epithelial cells: 87.7;Suprabasal keratinocytes: 142.1" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 87.7;Head and Neck Squamous Cell Carcinoma (TCGA): 80.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 56.6;head and neck cancer: 79.1" "Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Urothelial cells, Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA063914 Approved Vesicles,Cytosol NA NA "Cluster 58: Skin - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 14 Vesicles Cytosol "HPA063914: " "unprognostic (1.02e-2)" "unprognostic (2.36e-1)" "unprognostic (1.09e-1)" "unprognostic (2.14e-2)" "unprognostic (4.03e-1)" "validated prognostic unfavorable (2.22e-9)" "validated prognostic unfavorable (6.21e-4)" "potential prognostic unfavorable (9.88e-4)" "unprognostic (4.57e-3)" "unprognostic (7.26e-2)" "potential prognostic unfavorable (2.16e-4)" "unprognostic (4.61e-2)" "unprognostic (3.37e-2)" "unprognostic (1.73e-2)" "unprognostic (1.14e-1)" "potential prognostic unfavorable (2.26e-4)" "unprognostic (1.67e-3)" "unprognostic (1.65e-1)" "unprognostic (4.56e-1)" "unprognostic (3.09e-3)" IL21 "IL-21, Za11" ENSG00000138684 "Interleukin 21" Q9HBE4 4 122610108-122621066 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" Cytokine "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "lymphoid tissue: 5.5" "Cell type enhanced" "Detected in some" "Early spermatids: 16.8;Late primary spermatocytes: 8.7;Late spermatids: 8.6;T-cells: 3.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" Interleukin NA NA 55700 "Cluster 18: Lymphoid tissue - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 9: T-cells - Adaptive immunity: Regulation" IL21R CD360 ENSG00000103522 "Interleukin 21 receptor" Q9HBE5 16 27402174-27452042 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 7.1;lymphoid tissue: 22.9" "Cell type enhanced" "Detected in some" "B-cells: 25.3;cDC: 42.2;Innate lymphoid cells: 27.4;Kupffer cells: 22.5;NK-cells: 109.0;pDCs: 36.2;Plasma cells: 21.4;T-cells: 96.6;Thymic myoid cells: 65.3;Thymocytes: 20.3" "Cell type enriched" "Detected in some" 9 "leukocyte: 66.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "lymphoma: 53.9;Myeloma: 24.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Prostate - T-cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA042296 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 55: Lymphoma - Immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 1 "Plasma membrane, Cytosol" "HPA042296: " "unprognostic (4.61e-3)" "unprognostic (1.30e-1)" "unprognostic (8.04e-3)" "unprognostic (1.44e-1)" "unprognostic (1.24e-1)" "unprognostic (3.06e-2)" "unprognostic (5.04e-2)" "unprognostic (5.49e-2)" "unprognostic (1.79e-3)" "unprognostic (3.58e-2)" "unprognostic (1.88e-1)" "unprognostic (4.81e-2)" "unprognostic (3.10e-2)" "unprognostic (1.80e-1)" "unprognostic (2.89e-1)" "unprognostic (3.27e-1)" "unprognostic (4.59e-3)" "unprognostic (1.51e-1)" "unprognostic (6.43e-2)" "unprognostic (1.52e-2)" "unprognostic (5.36e-2)" "unprognostic (4.52e-2)" "unprognostic (1.56e-2)" "unprognostic (1.07e-2)" "unprognostic (4.50e-2)" "unprognostic (1.71e-1)" "unprognostic (1.40e-1)" IL22 "IL-21, IL-22, IL-D110, IL-TIF, ILTIF, MGC79382, MGC79384, TIFa, TIFIL-23, zcyto18" ENSG00000127318 "Interleukin 22" Q9GZX6 12 68248242-68253604 "Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "urinary bladder: 1.4" "Cell type enriched" "Detected in some" 6 "T-cells: 50.4" "Cell type enriched" "Detected in single" 4 "cerebellar inhibitory: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lymphoma: 1.7" "Region enriched" "Detected in some" 20 "cerebellum: 19.7" "Not detected" "Not detected" "Secreted to blood" Interleukin NA NA 86900 "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 9: T-cells - Adaptive immunity: Regulation" 4 IL22RA1 "CRF2-9, IL22R" ENSG00000142677 "Interleukin 22 receptor subunit alpha 1" Q8N6P7 1 24119771-24143140 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "pancreas: 189.0" "Cell type enhanced" "Detected in some" "Colonocytes: 31.9;Enterocytes: 93.3;Esophageal apical cells: 116.9;Goblet cells: 23.7;Pancreatic acinar cells: 183.3;Paneth cells: 58.0" "Group enriched" "Detected in some" 5 "ependymal cell: 2.1;hippocampal dentate gyrus: 2.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 11.2" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Kidney - Proximal tubular cells, Pituitary gland - Corticotropes, Prostate - Prostate basal glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 35: Non-specific - DNA binding" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 1: Enterocytes - Absorption and Digestion" 8 "unprognostic (5.88e-3)" "unprognostic (1.63e-1)" "unprognostic (2.46e-1)" "unprognostic (3.13e-2)" "unprognostic (1.14e-1)" "unprognostic (2.16e-1)" "unprognostic (6.57e-2)" "unprognostic (8.95e-2)" "unprognostic (5.05e-2)" "unprognostic (4.25e-1)" "unprognostic (1.18e-1)" "potential prognostic unfavorable (2.05e-4)" "unprognostic (4.57e-2)" "unprognostic (9.83e-2)" "unprognostic (3.12e-3)" "unprognostic (3.09e-1)" "unprognostic (2.03e-1)" "unprognostic (3.99e-3)" "unprognostic (2.48e-1)" "unprognostic (1.09e-1)" "unprognostic (8.12e-2)" "unprognostic (1.21e-1)" "unprognostic (2.42e-2)" "unprognostic (2.40e-1)" "unprognostic (3.83e-1)" "unprognostic (2.04e-2)" IL22RA2 "CRF2-S1, IL-22BP" ENSG00000164485 "Interleukin 22 receptor subunit alpha 2" Q969J5 6 137143820-137173648 "Predicted secreted proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "breast: 3.4;lymphoid tissue: 3.0" "Cell type enhanced" "Detected in some" "Breast hormone-responsive cells: 1.3;Breast secretory cells: 5.6;Macrophages: 2.3;monocytes: 2.3;Neutrophils: 1.8;Syncytiotrophoblasts: 3.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA030582, CAB034906" Uncertain "Secreted to blood" Receptor NA NA 40500000 "Cluster 18: Lymphoid tissue - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 82: Dendritic cells - Antigen presentation" "CAB034906: , HPA030582: " "unprognostic (1.80e-1)" "unprognostic (3.56e-1)" "unprognostic (5.00e-2)" IL23A "IL-23, IL-23A, IL23P19, P19, SGRF" ENSG00000110944 "Interleukin 23 subunit alpha" Q9NPF7 12 56334174-56340410 "FDA approved drug targets, Predicted secreted proteins" "Antiviral defense, Immunity, Inflammatory response, Innate immunity, Tissue remodeling" Cytokine "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "urinary bladder: 41.5" "Cell type enhanced" "Detected in many" "cDC: 54.9;Early primary spermatocytes: 34.9;Endometrial secretory cells: 18.8;Epididymal basal cells: 54.8;Esophageal apical cells: 18.1;Innate lymphoid cells: 24.9;Late primary spermatocytes: 37.7;monocytes: 19.8;Plasma cells: 17.1;Urothelial cells: 22.9" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 7 "MAIT T-cell: 14.2;memory B-cell: 19.0;memory CD4 T-cell: 25.8;memory CD8 T-cell: 12.5;naive B-cell: 21.6;naive CD4 T-cell: 28.2;naive CD8 T-cell: 17.7;T-reg: 15.6" "Group enriched" "Detected in many" 12 "B-cells: 21.6;T-cells: 28.2" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" "Region enhanced" "Detected in some" "white matter: 3.9" "Not detected" "Not detected" HPA001554 Approved Approved Cytosol "Secreted to blood" Interleukin NA NA 11000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 82: Dendritic cells - Antigen presentation" 5 Cytosol "HPA001554: " "unprognostic (8.92e-2)" "unprognostic (2.62e-1)" "unprognostic (1.52e-1)" "unprognostic (1.82e-1)" "unprognostic (2.16e-1)" "unprognostic (2.56e-2)" "unprognostic (1.11e-1)" "unprognostic (7.39e-3)" "potential prognostic unfavorable (7.16e-10)" "unprognostic (5.04e-3)" "unprognostic (1.15e-2)" "unprognostic (1.27e-1)" "potential prognostic unfavorable (1.30e-4)" "unprognostic (4.19e-2)" "unprognostic (1.43e-1)" "unprognostic (2.69e-1)" "unprognostic (2.98e-2)" "unprognostic (1.01e-1)" "unprognostic (1.05e-1)" "unprognostic (5.70e-1)" "unprognostic (1.55e-1)" "unprognostic (3.80e-1)" "unprognostic (3.62e-1)" "unprognostic (8.08e-2)" "unprognostic (4.35e-2)" "unprognostic (2.03e-1)" "unprognostic (1.50e-1)" IL23R IL-23R ENSG00000162594 "Interleukin 23 receptor" Q5VWK5 1 67138907-67259979 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 2.2;intestine: 1.0;testis: 1.1" "Cell type enriched" "Detected in some" 6 "Innate lymphoid cells: 142.9" "Cell type enriched" "Detected in single" 8 "leukocyte: 7.3" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 9 "MAIT T-cell: 24.1" "Lineage enriched" "Detected in single" 27 "T-cells: 24.1" "Cancer enhanced" "Detected in some" "Leukemia: 2.9;lymphoma: 3.3" "Adipose visceral - T-cells, Breast - T-cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA056427 Uncertain NA NA "Cluster 1: T-cells - Unknown function" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 2 "HPA056427: " "unprognostic (4.83e-2)" "unprognostic (3.47e-1)" IL24 "C49A, FISP, IL-24, IL10B, mda-7, Mob-5, ST16" ENSG00000162892 "Interleukin 24" Q13007 1 206897443-206904139 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" Apoptosis Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 5.5;urinary bladder: 13.5" "Group enriched" "Detected in some" 7 "Epicardial cells: 31.8;Pericytes: 120.6" "Cell type enriched" "Detected in single" 24 "leukocyte: 2.4" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 15.9" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 10 "B-cells: 5.4;T-cells: 3.7" "Cancer enriched" "Detected in many" 5 "skin cancer: 86.0" "Spleen - B-cells (Spleen)" "Not detected" "Not detected" "Not detected" "Not detected" CAB025972 Uncertain "Secreted to blood" Interleukin NA NA 140000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 69: Skin cancer - ECM organization" "Cluster 17: Non-specific - RNA processing" 12 "CAB025972: " "unprognostic (2.35e-1)" "potential prognostic favorable (5.46e-4)" "unprognostic (1.89e-1)" "unprognostic (2.79e-3)" "unprognostic (2.65e-1)" "unprognostic (9.55e-2)" "unprognostic (2.71e-1)" "unprognostic (4.89e-2)" "unprognostic (4.98e-2)" "unprognostic (7.03e-2)" "unprognostic (1.40e-1)" "unprognostic (4.77e-2)" "unprognostic (1.42e-1)" "unprognostic (1.74e-2)" "unprognostic (3.94e-2)" IL25 "IL-17E, IL-25, IL17E" ENSG00000166090 "Interleukin 25" Q9H293 14 23372809-23376403 "Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Late primary spermatocytes: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" CAB024864 Uncertain "Secreted to blood" Interleukin NA NA 35000 "Cluster 46: Skeletal myocytes - Muscle structure & formation" "CAB024864: " IL26 "AK155, IL-26" ENSG00000111536 "Interleukin 26" Q9NPH9 12 68201349-68225810 "Plasma proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "B-cells: 4.7;Cardiomyocytes: 8.4;Gastric chief cells: 3.3;Innate lymphoid cells: 15.6;Myosatellite cells: 21.8;Plasma cells: 13.2;T-cells: 14.3;Thymocytes: 3.4" "Cell type enriched" "Detected in some" 5 "deep-layer near-projecting: 24.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 17 "lymphoma: 29.4" "Low region specificity" "Detected in all" HPA077990 Approved "Golgi apparatus,Vesicles" "Secreted to blood" Interleukin NA NA 35700 "Cluster 71: Lymphoma - Inflammatory response" "Cluster 9: T-cells - Adaptive immunity: Regulation" "Golgi apparatus, Vesicles" "HPA077990: " IL27 "IL-27, IL-27A, IL27A, IL27p28, IL30, MGC71873, p28" ENSG00000197272 "Interleukin 27" Q8NEV9 16 28499362-28512051 "Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Antiviral protein, Cytokine" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "liver: 25.9" "Group enriched" "Detected in some" 4 "Hepatocytes: 24.5;Neutrophils: 12.1;Syncytiotrophoblasts: 33.5" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 1.5;deep-layer near-projecting: 1.3" "Cancer enriched" "Detected in some" 8 "Liver Hepatocellular Carcinoma (TCGA): 8.4" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "classical monocyte: 3.6;intermediate monocyte: 3.8" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" CAB024722 Approved "Secreted to blood" Interleukin NA NA 521000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 34: Testis cancer - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 1 "CAB024722: " "unprognostic (1.23e-1)" "unprognostic (1.18e-3)" "potential prognostic favorable (5.18e-4)" "potential prognostic unfavorable (5.85e-4)" IL27RA "CRL1, IL-27R, TCCR, WSX-1, WSX1, zcytor1" ENSG00000104998 "Interleukin 27 receptor subunit alpha" Q6UWB1 19 14031762-14053218 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 15.5" "Cell type enhanced" "Detected in some" "B-cells: 4.7;Brain excitatory neurons: 4.9;Ependymal cells: 8.1;Loop of henle epithelial cells: 4.4;monocytes: 3.7;NK-cells: 8.0;Other brain neurons: 4.9;Renal collecting duct intercalated cells: 3.8;Renal collecting duct principal cells: 4.6;T-cells: 6.7;Tuft cells: 11.5;Undifferentiated spermatogonia: 4.0" "Cell type enhanced" "Detected in many" "leukocyte: 44.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells, Spleen - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA073441 Approved Vesicles NA NA 150000 "Cluster 33: Non-specific - ATP binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 29: Forebrain - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 102: Non-specific - Mixed function" 25 Vesicles "HPA073441: " "unprognostic (3.00e-1)" "potential prognostic favorable (9.04e-6)" "unprognostic (2.33e-2)" "unprognostic (1.52e-1)" "unprognostic (4.67e-2)" "unprognostic (2.30e-1)" "potential prognostic unfavorable (2.56e-4)" "unprognostic (1.16e-1)" "unprognostic (2.70e-1)" "unprognostic (7.47e-2)" "unprognostic (5.89e-3)" "potential prognostic unfavorable (7.70e-4)" "unprognostic (1.60e-2)" "unprognostic (6.03e-3)" "unprognostic (3.25e-1)" "unprognostic (2.36e-1)" "unprognostic (2.20e-2)" "unprognostic (7.30e-2)" "unprognostic (1.04e-1)" "unprognostic (3.14e-3)" "unprognostic (2.64e-1)" "unprognostic (2.42e-1)" "unprognostic (1.69e-2)" "unprognostic (2.09e-1)" "unprognostic (8.83e-2)" "unprognostic (1.16e-1)" "unprognostic (1.92e-1)" "unprognostic (2.48e-2)" "unprognostic (1.62e-2)" "unprognostic (1.31e-1)" "unprognostic (3.35e-1)" IL2RA "CD25, IDDM10, IL2R" ENSG00000134460 "Interleukin 2 receptor subunit alpha" P01589 10 6010689-6062370 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins" Immunity Receptor "Cancer-related genes, Diabetes mellitus, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 17.5;lymphoid tissue: 16.7;urinary bladder: 10.1" "Cell type enhanced" "Detected in some" "B-cells: 45.2;Innate lymphoid cells: 160.1;Kupffer cells: 36.9;Macrophages: 51.3;Mast cells: 61.2;monocytes: 28.1;NK-cells: 18.6;T-cells: 75.8" "Cell type enriched" "Detected in some" 5 "leukocyte: 13.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 8 "basophil: 192.6;T-reg: 271.0" "Group enriched" "Detected in many" 15 "granulocytes: 192.6;T-cells: 271.0" "Cancer enriched" "Detected in some" 31 "lymphoma: 158.1" "Heart muscle - Macrophages, Kidney - Macrophages, Minor Salivary Gland - Macrophages, Pituitary gland - Macrophages, Thyroid gland - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB002419, HPA054622" Enhanced NA NA 230000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 8: Immune cells - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 9: T-cells - Adaptive immunity: Regulation" 1 "CAB002419: , HPA054622: " "unprognostic (1.10e-1)" "unprognostic (1.68e-1)" "unprognostic (8.88e-2)" "unprognostic (2.96e-2)" "unprognostic (7.10e-2)" "unprognostic (1.25e-1)" "unprognostic (4.10e-2)" "potential prognostic unfavorable (7.60e-4)" "unprognostic (1.11e-2)" "potential prognostic unfavorable (8.13e-5)" "unprognostic (4.84e-2)" "unprognostic (7.93e-3)" "unprognostic (4.14e-1)" "unprognostic (1.94e-1)" "potential prognostic unfavorable (2.71e-4)" "unprognostic (9.68e-2)" "unprognostic (1.29e-1)" "unprognostic (6.15e-2)" "unprognostic (3.65e-1)" "unprognostic (5.21e-2)" "potential prognostic unfavorable (8.26e-4)" "unprognostic (1.17e-1)" "unprognostic (1.36e-1)" "unprognostic (7.94e-2)" "unprognostic (1.32e-1)" "unprognostic (7.33e-2)" "unprognostic (7.39e-2)" "unprognostic (4.95e-3)" IL2RB "CD122, IL15RB" ENSG00000100385 "Interleukin 2 receptor subunit beta" P14784 22 37118666-37175118 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Host-virus interaction" Receptor "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 32.9;lymphoid tissue: 46.4" "Cell type enhanced" "Detected in some" "Extravillous trophoblasts: 203.4;Innate lymphoid cells: 49.7;NK-cells: 288.1;T-cells: 81.2" "Cell type enriched" "Detected in single" 131 "leukocyte: 108.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 4 "gdT-cell: 49.8;NK-cell: 184.0" "Group enriched" "Detected in many" 30 "NK-cells: 184.0;T-cells: 49.8" "Cancer enriched" "Detected in some" 8 "lymphoma: 69.8" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - NK-cells (Liver), Minor Salivary Gland - T-cells, Pancreas - T-cells, Prostate - T-cells, Thyroid gland - T-cells" "Region enriched" "Detected in single" 7 "basal ganglia: 1.8" "Low region specificity" "Detected in many" HPA062657 Enhanced NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 38: Sub-cortical - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 9 "HPA062657: " "unprognostic (3.48e-2)" "unprognostic (4.47e-3)" "unprognostic (1.98e-3)" "unprognostic (3.00e-3)" "unprognostic (1.07e-1)" "unprognostic (8.58e-3)" "unprognostic (1.16e-2)" "unprognostic (2.22e-1)" "unprognostic (2.52e-3)" "unprognostic (1.76e-1)" "unprognostic (1.54e-1)" "unprognostic (2.67e-2)" "potential prognostic unfavorable (5.33e-4)" "unprognostic (3.82e-1)" "unprognostic (2.13e-2)" "unprognostic (1.81e-1)" "unprognostic (1.84e-1)" "unprognostic (6.57e-2)" "unprognostic (2.43e-1)" "unprognostic (9.56e-2)" "unprognostic (9.04e-2)" "unprognostic (2.67e-1)" "unprognostic (1.42e-1)" "unprognostic (2.83e-1)" "unprognostic (1.05e-1)" "unprognostic (1.91e-2)" "potential prognostic favorable (6.40e-4)" "unprognostic (9.05e-2)" "unprognostic (1.03e-1)" "unprognostic (1.12e-2)" "unprognostic (3.12e-1)" IL2RG "CD132, CIDX, IMD4, SCIDX1" ENSG00000147168 "Interleukin 2 receptor subunit gamma" P31785 X 71107404-71112108 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" Receptor "Cancer-related genes, Disease variant, FDA approved drug targets, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 109.3;lymphoid tissue: 317.8" "Cell type enhanced" "Detected in some" "B-cells: 3.2;cDC: 2.3;Enterocytes: 2.0;Hematopoietic stem cells: 1.9;Innate lymphoid cells: 7.7;Megakaryocyte progenitors: 2.0;Neutrophils: 7.4;NK-cells: 11.3;pDCs: 3.2;Plasma cells: 9.3;T-cells: 6.8;Thymocytes: 2.5" "Cell type enriched" "Detected in single" 116 "leukocyte: 11.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 8 "Leukemia: 207.1;lymphoma: 145.1;Myeloma: 354.9" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Colon - T-cells, Liver - T-cells, Minor Salivary Gland - Plasma cells, Pancreas - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Spleen - T-cells, Thyroid gland - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA046641, CAB080341" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA 14000 "Cluster 1: T-cells - Unknown function" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 78: Plasma cells - Antibody production & ER-stress response" 9 "Plasma membrane" Nucleoplasm "CAB080341: , HPA046641: " "unprognostic (1.11e-2)" "unprognostic (4.75e-3)" "unprognostic (4.55e-3)" "unprognostic (6.80e-2)" "unprognostic (2.87e-1)" "unprognostic (4.46e-2)" "unprognostic (1.29e-2)" "unprognostic (1.05e-1)" "unprognostic (1.13e-3)" "unprognostic (3.08e-1)" "unprognostic (1.62e-2)" "unprognostic (1.23e-1)" "unprognostic (1.33e-2)" "unprognostic (6.30e-2)" "unprognostic (2.15e-1)" "unprognostic (1.15e-1)" "unprognostic (9.48e-2)" "unprognostic (3.91e-1)" "unprognostic (9.50e-2)" "unprognostic (5.57e-2)" "unprognostic (8.45e-2)" "unprognostic (1.66e-1)" "unprognostic (1.01e-2)" "unprognostic (2.24e-1)" "unprognostic (2.20e-1)" "unprognostic (1.56e-2)" "potential prognostic favorable (2.33e-4)" "unprognostic (1.70e-1)" "unprognostic (4.79e-2)" "unprognostic (6.17e-2)" "unprognostic (2.32e-2)" IL3 "IL-3, MCGF, MGC79398, MGC79399, MULTI-CSF" ENSG00000164399 "Interleukin 3" P08700 5 132060655-132063204 "Predicted secreted proteins" "Cytokine, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" Interleukin NA NA 17800 "Cluster 9: Non-specific - Receptor signaling" "Cluster 49: HMC-1 - Innate immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 2 IL31 IL-31 ENSG00000204671 "Interleukin 31" Q6EBC2 12 122172029-122174221 "Predicted secreted proteins" Immunity Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Early spermatids: 1.3;Epicardial cells: 4.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" CAB025657 Uncertain "Secreted to blood" Interleukin NA NA 37800 "Cluster 50: Lymphoma - Unknown function" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 1 "CAB025657: " IL31RA "CRL, CRL3, GLM-R, Glmr, IL-31RA" ENSG00000164509 "Interleukin 31 receptor A" Q8NI17 5 55851357-55922854 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Immunity Receptor "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "blood vessel: 2.2;bone marrow: 1.5;lymphoid tissue: 1.9;testis: 1.5" "Cell type enhanced" "Detected in some" "Early spermatids: 5.7;Late primary spermatocytes: 4.4;Medullary thymic epithelial cells: 14.4;Mesothelial cells: 8.3;Monocyte progenitors: 24.8;monocytes: 4.9;Myonuclei: 15.5;Oocytes: 4.6;Prostatic glandular cells: 6.1;Smooth muscle cells: 7.9" "Cell type enhanced" "Detected in some" "amygdala excitatory: 2.5;deep-layer corticothalamic and 6b: 3.2" "Cancer enhanced" "Detected in some" "Head and Neck Squamous Cell Carcinoma (TCGA): 1.7;Lung Adenocarcinoma (TCGA): 1.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Prostate glandular cells, Skin - Outer root sheath cells, Testis - Early spermatids" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebral cortex: 1.6" HPA068114 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 39: Testis - Nuclear processes" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 46: Skeletal myocytes - Muscle structure & formation" "Plasma membrane, Cytosol" "HPA068114: " "unprognostic (6.69e-3)" "unprognostic (1.11e-1)" "unprognostic (3.29e-3)" "unprognostic (4.94e-2)" "unprognostic (4.40e-1)" "potential prognostic unfavorable (3.29e-5)" IL32 "NK4, TAIF, TAIFb, TAIFd" ENSG00000008517 "Interleukin 32" P24001 16 3065297-3082192 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 830.9;pancreas: 685.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 417.0;Colonocytes: 1212.8;Enterocytes: 4882.8;Epididymal efferent duct absorptive cells: 419.5;NK-cells: 570.8;Pancreatic acinar cells: 1531.1;Pancreatic duct cells: 848.1;T-cells: 983.9" "Cell type enriched" "Detected in some" 4 "leukocyte: 288.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "T-reg: 4640.3" "Lineage enriched" "Detected in all" 8 "T-cells: 4640.3" "Cancer enhanced" "Detected in all" "Kidney cancer: 674.0" "Kidney - Proximal tubular cells, Pancreas - Ductal cells" "HPA029397, CAB030029" Uncertain "Secreted to blood" Interleukin NA NA 46100 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 47: Endothelial cells - Vasculature" "Cluster 59: Leukemia - T-cell receptor" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 3 "CAB030029: , HPA029397: " "unprognostic (7.01e-2)" "unprognostic (3.68e-2)" "unprognostic (5.69e-2)" "unprognostic (1.90e-2)" "unprognostic (2.41e-1)" "unprognostic (1.77e-1)" "potential prognostic unfavorable (6.67e-4)" "unprognostic (1.18e-2)" "unprognostic (6.12e-2)" "unprognostic (9.39e-2)" "unprognostic (1.38e-1)" "unprognostic (1.31e-1)" "unprognostic (8.32e-2)" "unprognostic (2.93e-2)" "unprognostic (1.31e-3)" "potential prognostic unfavorable (8.02e-4)" "unprognostic (2.48e-2)" "unprognostic (1.98e-1)" "unprognostic (1.85e-2)" "unprognostic (9.98e-2)" "unprognostic (8.62e-2)" "unprognostic (1.22e-3)" "unprognostic (2.03e-2)" "unprognostic (2.57e-1)" "unprognostic (2.05e-1)" "unprognostic (2.31e-3)" "potential prognostic favorable (2.23e-4)" "unprognostic (6.86e-2)" "unprognostic (5.67e-2)" "unprognostic (4.43e-2)" "unprognostic (1.75e-2)" IL33 "C9orf26, DKFZp586H0523, DVS27, IL1F11, NF-HEV" ENSG00000137033 "Interleukin 33" O95760 9 6215786-6257983 "Predicted intracellular proteins, Predicted secreted proteins" Transcription Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 114.2" "Cell type enhanced" "Detected in many" "Astrocytes: 81.6;Bergmann glia: 70.5;Breast lactating cells: 91.7;Fibro-adipogenic progenitors: 65.4;Fibroblasts: 100.1;Gastric chief cells: 76.4;Lymphatic endothelial cells: 132.1;Medullary thymic epithelial cells: 127.2;Mucous neck cells: 128.4;Respiratory basal cells: 262.6;Respiratory secretory cells: 92.5;Vascular endothelial cells: 185.7" "Cell type enhanced" "Detected in some" "astrocyte: 86.9;Bergmann glia: 76.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "colorectal cancer: 24.6;Rhabdoid: 15.7;Sarcoma: 26.2;thyroid cancer: 8.9" "Adrenal gland - Endothelial cells, Heart muscle - Fibroblasts, Liver - Vascular endothelial cells, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007057, HPA022899, HPA024426" Supported Supported Nucleoplasm,Vesicles "Secreted to blood" Interleukin NA NA "Cluster 13: Lung - Secretion" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 6 Nucleoplasm Vesicles "CAB007057: , HPA022899: , HPA024426: " "unprognostic (7.47e-3)" "unprognostic (1.17e-3)" "unprognostic (9.27e-3)" "unprognostic (1.13e-2)" "unprognostic (1.16e-2)" "unprognostic (1.41e-2)" "unprognostic (2.48e-1)" "unprognostic (5.28e-2)" "unprognostic (1.45e-1)" "unprognostic (1.05e-1)" "potential prognostic favorable (2.34e-5)" "unprognostic (1.34e-2)" "potential prognostic unfavorable (6.68e-5)" "unprognostic (3.70e-3)" "unprognostic (3.24e-3)" "potential prognostic favorable (4.43e-4)" "unprognostic (2.27e-2)" "unprognostic (2.53e-1)" "unprognostic (1.08e-1)" "unprognostic (1.75e-1)" "unprognostic (1.84e-1)" "unprognostic (2.63e-1)" "unprognostic (5.19e-2)" "unprognostic (1.51e-1)" "unprognostic (7.21e-2)" "unprognostic (9.60e-2)" "unprognostic (1.09e-1)" "unprognostic (1.43e-3)" "unprognostic (9.85e-2)" "unprognostic (9.30e-2)" "unprognostic (9.85e-2)" IL34 "C16orf77, IL-34, MGC34647" ENSG00000157368 "Interleukin 34" Q6ZMJ4 16 70579895-70660682 "Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Cytokine, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 103.5;skin 1: 62.0" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 79.2;Breast secretory cells: 77.1;Esophageal apical cells: 230.1;Esophageal suprabasal cells: 62.2;Lacrimal acinar cells: 75.2;Peritubular myoid cells: 63.2;Salivary duct cells: 61.2;Schwann cells: 116.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 13 "eosinophil: 18.6" "Lineage enriched" "Detected in single" 187 "granulocytes: 18.6" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Adipose progenitor cells, Breast - Breast myoepithelial cells, Colon - Enteric glia cells, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skin - Keratinocyte (other), Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" Interleukin NA NA 57100 "Cluster 22: Eosinophils - Transcription" "Cluster 5: Spleen - Immune response" "Cluster 29: Forebrain - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 61: Schwann cells & Melanocytes - Mixed function" 1 "unprognostic (1.61e-1)" "unprognostic (4.65e-3)" "unprognostic (2.52e-3)" "potential prognostic favorable (1.69e-4)" "unprognostic (3.08e-2)" "unprognostic (5.42e-2)" "unprognostic (1.37e-2)" "unprognostic (1.16e-1)" "unprognostic (4.21e-3)" "unprognostic (8.38e-3)" "potential prognostic unfavorable (3.79e-4)" "unprognostic (1.61e-1)" "unprognostic (9.50e-3)" "unprognostic (1.01e-1)" "unprognostic (6.16e-2)" "unprognostic (1.23e-3)" "unprognostic (1.75e-1)" "unprognostic (1.63e-1)" "unprognostic (9.49e-2)" "potential prognostic unfavorable (5.61e-4)" "unprognostic (1.61e-1)" "unprognostic (9.28e-3)" "unprognostic (1.08e-1)" "unprognostic (1.53e-1)" "unprognostic (1.01e-1)" "unprognostic (1.37e-3)" "unprognostic (1.65e-1)" "unprognostic (8.92e-3)" "unprognostic (3.06e-2)" "unprognostic (1.06e-1)" "unprognostic (4.54e-1)" IL36A "FIL1, FIL1E, IL-1F6, IL1(EPSILON), IL1F6, MGC129552, MGC129553" ENSG00000136694 "Interleukin 36 alpha" Q9UHA7 2 113005459-113008044 "Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "esophagus: 385.8;lymphoid tissue: 108.2" "Cell type enriched" "Detected in some" 22 "Esophageal apical cells: 214.6" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Head and Neck Squamous Cell Carcinoma (TCGA): 13.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "cervical cancer: 1.2" "Not detected" "Not detected" "Secreted to blood" Interleukin NA NA 249000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 59: Leukemia - T-cell receptor" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 5 "unprognostic (1.57e-1)" "unprognostic (2.72e-3)" "unprognostic (2.33e-1)" "unprognostic (2.39e-1)" "unprognostic (4.07e-1)" IL36B "FIL1, FILI-(ETA), IL-1F8, IL-1H2, IL1-ETA, IL1F8, IL1H2, MGC126880, MGC126882" ENSG00000136696 "Interleukin 36 beta" Q9NZH7 2 113022089-113052867 "Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 2.1;lymphoid tissue: 3.5;skin 1: 8.0" "Cell type enriched" "Detected in some" 32 "Esophageal apical cells: 54.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Head and Neck Squamous Cell Carcinoma (TCGA): 2.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Bone cancer: 1.6;Brain cancer: 3.0" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" HPA035664 Uncertain "Secreted to blood" Interleukin NA NA 8560 "Cluster 58: Skin - Keratinization" "Cluster 72: Neuronal - Signal transduction" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 1 "HPA035664: " "unprognostic (3.50e-2)" IL36G "IL-1F9, IL-1H1, IL-1RP2, IL1E, IL1F9, IL1H1" ENSG00000136688 "Interleukin 36 gamma" Q9NZH8 2 112973203-112985658 "Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "cervix: 10.8;esophagus: 13.3;lymphoid tissue: 36.9;skin 1: 28.0" "Group enriched" "Detected in some" 7 "Esophageal apical cells: 370.7;Esophageal suprabasal cells: 124.6;Ocular epithelial cells: 324.4" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 21.7;Head and Neck Squamous Cell Carcinoma (TCGA): 65.8;Lung Squamous Cell Carcinoma (TCGA): 21.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Gallbladder cancer: 50.3;head and neck cancer: 17.3" "Not detected" "Not detected" HPA068168 Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" Interleukin NA NA 37100 38000 "Cluster 58: Skin - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" Cytosol "Nucleoplasm, Plasma membrane" "HPA068168: " "unprognostic (5.91e-3)" "unprognostic (2.19e-1)" "unprognostic (9.65e-2)" "unprognostic (1.13e-1)" "unprognostic (3.43e-1)" "unprognostic (3.58e-2)" "unprognostic (1.87e-1)" "unprognostic (4.89e-2)" "unprognostic (1.37e-2)" "unprognostic (4.57e-1)" "unprognostic (3.83e-3)" IL36RN "FIL1, FIL1(DELTA), FIL1D, IL-1F5, IL1F5, IL1HY1, IL1L1, IL1RP3, IL36RA, MGC29840" ENSG00000136695 "Interleukin 36 receptor antagonist" Q9UBH0 2 113058638-113065382 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Innate immunity" Cytokine "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 26.1;lymphoid tissue: 42.2;skin 1: 60.0" "Cell type enriched" "Detected in some" 13 "Esophageal apical cells: 326.6" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Head and Neck Squamous Cell Carcinoma (TCGA): 46.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 3.6" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Secreted to blood" Interleukin NA NA 107000 "Cluster 58: Skin - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 84: Apical squamous epithelium - Cornification" 26 "unprognostic (2.08e-2)" "unprognostic (8.12e-2)" "unprognostic (3.59e-2)" "unprognostic (2.73e-2)" "unprognostic (1.22e-3)" "unprognostic (1.49e-2)" "unprognostic (1.08e-1)" "unprognostic (2.50e-1)" IL37 "FIL1, FIL1(ZETA), FIL1Z, IL-1F7, IL-1H4, IL-1RP1, IL1F7" ENSG00000125571 "Interleukin 37" Q9NZH6 2 112911165-112918882 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skin 1: 114.2" "Cell type enhanced" "Detected in some" "Gastric chief cells: 1.1;Goblet cells: 1.3;Late spermatids: 3.1" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 8 "Lung Adenocarcinoma (TCGA): 24.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 5.5" "Skin - Keratinocyte (granular)" "HPA045873, HPA054371, HPA057950" Uncertain Supported Nucleoplasm,Vesicles,Cytosol "Secreted to blood" Interleukin NA NA 76700 "Cluster 37: Skin - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 6 "Nucleoplasm, Vesicles, Cytosol" "HPA045873: , HPA054371: , HPA057950: " "unprognostic (3.00e-3)" "unprognostic (3.57e-2)" "unprognostic (1.48e-2)" "unprognostic (4.00e-2)" "unprognostic (3.01e-1)" "unprognostic (1.68e-1)" "unprognostic (5.16e-2)" "unprognostic (4.14e-2)" "unprognostic (3.45e-1)" IL3RA CD123 ENSG00000185291 "Interleukin 3 receptor subunit alpha" P26951 X 1336616-1382689 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Epicardial cells: 504.9;pDCs: 993.0" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 2669.0" "Lineage enriched" "Detected in all" 4 "granulocytes: 2669.0" "Cancer enhanced" "Detected in many" "Leukemia: 20.7" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Pancreas - Endothelial cells, Pituitary gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid gland - Endothelial cells" "HPA003539, CAB018374" Uncertain NA NA "Cluster 41: Basophils - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 6: Non-specific - Immune response" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 18 "CAB018374: , HPA003539: " "unprognostic (2.78e-2)" "unprognostic (1.01e-3)" "unprognostic (5.83e-2)" "unprognostic (1.97e-2)" "unprognostic (8.87e-2)" "unprognostic (1.87e-1)" "unprognostic (3.55e-1)" "unprognostic (5.44e-3)" "unprognostic (1.43e-1)" "validated prognostic favorable (2.65e-4)" "validated prognostic favorable (2.52e-4)" "unprognostic (2.17e-3)" "unprognostic (2.45e-1)" "unprognostic (9.21e-2)" "unprognostic (1.24e-1)" "unprognostic (1.16e-3)" "unprognostic (2.90e-1)" "unprognostic (1.79e-1)" "unprognostic (1.89e-1)" "unprognostic (2.50e-2)" "unprognostic (3.20e-2)" "unprognostic (1.19e-2)" "unprognostic (5.59e-2)" "unprognostic (4.27e-2)" "unprognostic (5.45e-2)" "unprognostic (1.97e-2)" "unprognostic (1.90e-3)" "unprognostic (1.42e-1)" "unprognostic (5.39e-2)" IL4 "BCGF-1, BCGF1, BSF1, IL-4, MGC79402" ENSG00000113520 "Interleukin 4" P05112 5 132673986-132682678 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "B-cell activation" "Cytokine, Growth factor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Epicardial cells: 2.3;Kupffer cells: 1.0;Retinal amacrine cells: 2.6;Retinal horizontal cells: 2.0;T-cells: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 862 "basophil: 476.8" "Lineage enriched" "Detected in single" 862 "granulocytes: 476.8" "Cancer enhanced" "Detected in single" "lymphoma: 1.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA072995, CAB078477" Approved "Secreted to blood" Interleukin NA NA 13600 "Cluster 46: Basophils - Proteolysis" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 50: Lymphoma - Unknown function" "Cluster 9: T-cells - Adaptive immunity: Regulation" 3 "CAB078477: , HPA072995: " IL4I1 FIG1 ENSG00000104951 "Interleukin 4 induced 1" Q96RQ9 19 49889654-49929539 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "lymphoid tissue: 17.1;testis: 27.5" "Cell type enhanced" "Detected in many" "cDC: 244.4;Early spermatids: 67.2;Fallopian secretory cells: 139.8;Innate lymphoid cells: 379.1;Late primary spermatocytes: 124.3;Macrophages: 48.4" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 4.0" "Cancer enhanced" "Detected in all" "Ovary Serous Cystadenocarcinoma (TCGA): 66.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 103.5" "Group enriched" "Detected in many" 6 "monocytes: 36.6;T-cells: 103.5" "Cancer enhanced" "Detected in many" "lymphoma: 33.1;Myeloma: 18.6" "Spleen - T-cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA045598 Enhanced Supported Acrosome "Secreted to blood" Immunity NA NA "Cluster 1: T-cells - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 50: Lymphoma - Unknown function" "Cluster 82: Dendritic cells - Antigen presentation" 3 Acrosome "HPA045598: " "unprognostic (1.37e-1)" "unprognostic (4.51e-2)" "unprognostic (7.75e-2)" "unprognostic (1.94e-1)" "unprognostic (8.16e-2)" "unprognostic (7.89e-2)" "potential prognostic unfavorable (2.88e-4)" "unprognostic (3.30e-1)" "unprognostic (3.16e-2)" "unprognostic (1.32e-1)" "potential prognostic unfavorable (9.89e-4)" "unprognostic (3.66e-2)" "potential prognostic unfavorable (1.44e-4)" "potential prognostic unfavorable (8.69e-4)" "unprognostic (1.64e-1)" "unprognostic (1.15e-1)" "unprognostic (2.60e-2)" "unprognostic (4.75e-2)" "unprognostic (9.21e-2)" "unprognostic (5.63e-2)" "unprognostic (4.14e-2)" "unprognostic (2.03e-1)" "unprognostic (1.90e-3)" "unprognostic (2.49e-1)" "unprognostic (1.62e-2)" "unprognostic (1.49e-1)" "unprognostic (6.03e-3)" "unprognostic (1.82e-1)" "unprognostic (1.06e-2)" "unprognostic (2.17e-1)" "unprognostic (2.80e-1)" IL4R CD124 ENSG00000077238 "Interleukin 4 receptor" P24394 16 27313668-27364778 "Cancer-related genes, CD markers, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" Immunity Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epicardial cells: 277.4;Mast cells: 319.7;Neutrophil progenitors: 208.4;Neutrophils: 757.8" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 90.5;endothelial cell: 197.2;vascular associated smooth muscle cell: 79.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "naive B-cell: 77.1" "Group enriched" "Detected in all" 5 "B-cells: 77.1;granulocytes: 31.1" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 139.2" "Kidney - Endothelial cells, Liver - Neutrophils, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB004451, HPA050124, HPA070380" Enhanced Supported "Nucleoplasm,Plasma membrane,Centriolar satellite" "Secreted to blood" Receptor NA NA 38500 10000 "Cluster 34: B-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 12 "Plasma membrane" "Nucleoplasm, Centriolar satellite" "CAB004451: , HPA050124: , HPA070380: " "unprognostic (1.22e-2)" "unprognostic (2.18e-1)" "unprognostic (2.80e-3)" "unprognostic (2.44e-3)" "unprognostic (2.15e-1)" "unprognostic (6.86e-2)" "unprognostic (1.02e-2)" "unprognostic (3.53e-1)" "unprognostic (6.16e-2)" "unprognostic (1.86e-1)" "unprognostic (1.97e-1)" "unprognostic (8.28e-2)" "unprognostic (2.76e-1)" "unprognostic (7.42e-2)" "potential prognostic favorable (2.13e-4)" "unprognostic (7.35e-2)" "unprognostic (2.36e-2)" "unprognostic (2.99e-3)" "potential prognostic unfavorable (3.26e-4)" "unprognostic (4.67e-2)" "unprognostic (1.67e-1)" "unprognostic (9.43e-2)" "unprognostic (1.50e-3)" "unprognostic (1.59e-1)" "unprognostic (1.54e-2)" "unprognostic (2.65e-1)" "unprognostic (3.40e-1)" "unprognostic (1.21e-2)" "unprognostic (2.80e-1)" "unprognostic (1.69e-1)" "unprognostic (5.20e-2)" IL5 "EDF, IL-5, TRF" ENSG00000113525 "Interleukin 5" P05113 5 132541445-132556838 "Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Cytokine, Growth factor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "testis: 4.8" "Cell type enhanced" "Detected in some" "Adipocytes: 12.4;Cardiomyocytes: 38.5;Early primary spermatocytes: 12.4;Epicardial cells: 43.2;Fibro-adipogenic progenitors: 7.8;Late primary spermatocytes: 37.8;Mast cells: 12.2;Myonuclei: 7.0" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "memory B-cell: 1.4" "Lineage enriched" "Detected in single" 8 "B-cells: 1.4" "Cancer enriched" "Detected in single" 4 "lymphoma: 1.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB010304 Approved "Secreted to blood" Interleukin NA NA 4130 "Cluster 57: Testis - Spermatogenesis" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 59: Leukemia - T-cell receptor" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 4 "CAB010304: " IL5RA "CD125, CDw125, IL5R" ENSG00000091181 "Interleukin 5 receptor subunit alpha" Q01344 3 3066324-3126613 "CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 5.9;fallopian tube: 10.1" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 22.4;Corticotrophs: 23.0;Endometrial ciliated cells: 52.6;Ependymal cells: 90.1;Epididymal efferent duct ciliated cells: 44.9;Fallopian tube ciliated cells: 52.6;Late primary spermatocytes: 37.7;Mast cells: 71.9;Plasma cells: 39.7;Respiratory ciliated cells: 97.1" "Cell type enriched" "Detected in many" 4 "ependymal cell: 101.1" "Cancer enhanced" "Detected in some" "Prostate Adenocarcinoma (TCGA): 3.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 190 "basophil: 179.4;eosinophil: 356.1" "Lineage enriched" "Detected in many" 253 "granulocytes: 356.1" "Cancer enhanced" "Detected in some" "lymphoma: 2.7;Myeloma: 8.5" "Adipose subcutaneous - Mast cells, Colon - Mast cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - Plasma cells, Prostate - Prostate glandular cells, Spleen - Plasma cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Intracellular and membrane" Receptor NA NA 61000 "Cluster 22: Eosinophils - Transcription" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 50: Lymphoma - Unknown function" "Cluster 58: Mast cells - Allergic inflammatory responses" 9 "unprognostic (7.54e-2)" "unprognostic (1.46e-1)" "unprognostic (1.72e-3)" "unprognostic (1.09e-1)" "unprognostic (3.08e-2)" "unprognostic (4.14e-2)" "unprognostic (1.74e-2)" IL6 "BSF2, HGF, HSF, IFNB2, IL-6" ENSG00000136244 "Interleukin 6" P05231 7 22725884-22732002 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Acute phase" "Cytokine, Growth factor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 187.7;lung: 140.6;urinary bladder: 256.4" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 91.5;Endometrial glandular cells: 80.2;Endometrial luminal cells: 715.7;Fibroblasts: 152.1;Pericytes: 203.4;Pituicytes/FSCs: 79.0;Vascular endothelial cells: 221.9;Vascular smooth muscle cells: 566.0" "Group enriched" "Detected in some" 12 "central nervous system macrophage: 3.4;choroid plexus epithelial cell: 2.1;endothelial cell: 3.1;vascular associated smooth muscle cell: 5.1" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "choroid plexus: 15.1" "Group enriched" "Detected in some" 47 "memory B-cell: 4.1;naive B-cell: 5.2" "Lineage enriched" "Detected in single" 52 "B-cells: 5.2" "Cancer enhanced" "Detected in many" "Kidney cancer: 219.1" "Breast - Endothelial cells, Colon - Neutrophils" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB023406, CAB072821" Supported Approved Vesicles "Secreted to blood" "Acute phase" NA NA 5700 280000 "Cluster 14: Non-specific - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 36: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 103: Non-specific - Basic cellular processes" 7 Vesicles "CAB023406: , CAB072821: " "unprognostic (3.09e-1)" "unprognostic (2.74e-2)" "unprognostic (5.92e-3)" "unprognostic (2.89e-2)" "unprognostic (2.90e-1)" "unprognostic (3.00e-1)" "unprognostic (3.88e-3)" "unprognostic (7.66e-2)" "unprognostic (1.96e-2)" "unprognostic (1.11e-1)" "potential prognostic unfavorable (2.42e-6)" "unprognostic (3.56e-2)" "unprognostic (3.64e-2)" "unprognostic (1.64e-2)" "unprognostic (6.65e-2)" "unprognostic (2.31e-2)" "unprognostic (6.49e-3)" "unprognostic (4.43e-1)" "unprognostic (1.91e-1)" "unprognostic (2.06e-1)" "unprognostic (1.00e-2)" "unprognostic (1.43e-2)" "unprognostic (4.08e-2)" "unprognostic (2.84e-1)" "unprognostic (5.49e-2)" "unprognostic (2.62e-1)" "unprognostic (1.44e-3)" "unprognostic (1.28e-2)" "unprognostic (4.01e-2)" "unprognostic (1.51e-2)" IL6R "CD126, gp80, IL-1Ra, IL-6R, IL6RA" ENSG00000160712 "Interleukin 6 receptor" P08887 1 154405193-154469450 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 58.5;skeletal muscle: 90.6" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 213.1;Hepatocytes: 259.6;Monocyte progenitors: 204.2;monocytes: 308.2;Neutrophil progenitors: 206.0;Neutrophils: 773.0;Proximal tubule cells: 305.2" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 194.2;endothelial cell: 88.4;fibroblast: 101.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 89.4" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Myeloma: 83.8" "Pituitary gland - Corticotropes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted to blood" Receptor NA NA 24800000 4400000 "Cluster 7: Non-specific - Innate immune response" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 7 "unprognostic (1.11e-1)" "unprognostic (1.75e-1)" "unprognostic (5.77e-2)" "unprognostic (2.50e-1)" "unprognostic (3.95e-2)" "unprognostic (2.54e-1)" "unprognostic (8.01e-2)" "unprognostic (7.43e-3)" "unprognostic (4.60e-2)" "unprognostic (5.42e-2)" "potential prognostic favorable (6.13e-6)" "unprognostic (7.34e-3)" "unprognostic (1.54e-2)" "unprognostic (2.49e-1)" "unprognostic (1.86e-1)" "unprognostic (1.09e-2)" "unprognostic (7.06e-2)" "unprognostic (2.88e-2)" "unprognostic (1.06e-1)" "unprognostic (7.01e-2)" "unprognostic (8.25e-2)" "potential prognostic favorable (3.20e-4)" "unprognostic (2.03e-2)" "unprognostic (3.80e-1)" "unprognostic (1.66e-1)" "unprognostic (2.35e-1)" "unprognostic (2.15e-1)" "unprognostic (2.04e-2)" "unprognostic (2.21e-1)" "unprognostic (2.87e-1)" "unprognostic (7.90e-2)" IL6ST "CD130, GP130, IL-6RB, sGP130" ENSG00000134352 "Interleukin 6 cytokine family signal transducer" P40189 5 55935095-55995022 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Host-virus interaction" Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial glandular cells: 1204.2;Microglia: 759.0;Platelets: 681.9" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 924.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 22.8" "Lineage enriched" "Detected in many" 5 "T-cells: 22.8" "Low cancer specificity" "Detected in all" "Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010558, CAB025784" Approved Supported "Golgi apparatus,Plasma membrane" "Secreted to blood" Receptor NA NA 48000000 "Cluster 33: Non-specific - ATP binding" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 51: Secretory epithelial cells - Mixed function" 22 "Plasma membrane" "Golgi apparatus" "CAB025784: , HPA010558: " "unprognostic (3.34e-2)" "unprognostic (9.54e-3)" "unprognostic (6.35e-2)" "unprognostic (4.58e-2)" "unprognostic (3.44e-1)" "unprognostic (5.93e-3)" "unprognostic (1.49e-1)" "potential prognostic unfavorable (3.79e-5)" "unprognostic (1.62e-2)" "unprognostic (1.27e-2)" "potential prognostic favorable (3.47e-5)" "unprognostic (6.75e-3)" "unprognostic (1.20e-1)" "unprognostic (7.66e-2)" "unprognostic (2.13e-3)" "unprognostic (4.31e-3)" "unprognostic (2.61e-1)" "unprognostic (5.52e-2)" "unprognostic (2.62e-1)" "unprognostic (2.74e-1)" "unprognostic (5.83e-3)" "unprognostic (1.16e-2)" "unprognostic (4.67e-2)" "unprognostic (7.33e-2)" "unprognostic (6.47e-3)" "unprognostic (1.68e-1)" "unprognostic (2.75e-2)" "unprognostic (5.11e-3)" "unprognostic (4.99e-1)" "unprognostic (3.20e-1)" "unprognostic (1.40e-1)" IL7 IL-7 ENSG00000104432 "Interleukin 7" P13232 8 78675743-78805523 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cytokine, Growth factor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 158.3;Early spermatids: 156.7;Endometrial ciliated cells: 142.1;Epicardial cells: 259.3;Fibro-adipogenic progenitors: 191.2;Late primary spermatocytes: 135.6;Late spermatids: 246.7;Lymphatic endothelial cells: 202.9;Respiratory ciliated cells: 135.6;Retinal ganglion cells: 177.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 9.8;naive B-cell: 8.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA019590 Approved "Secreted to blood" Interleukin NA NA 60700 "Cluster 32: Basophils - Transcription" "Cluster 77: Intestine - Digestion" "Cluster 44: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 1 "HPA019590: " "unprognostic (8.03e-3)" "unprognostic (3.63e-3)" "unprognostic (1.88e-2)" "unprognostic (9.68e-3)" "unprognostic (4.63e-2)" "unprognostic (6.34e-2)" "potential prognostic unfavorable (3.50e-4)" "unprognostic (4.73e-3)" "unprognostic (4.21e-1)" "unprognostic (4.00e-3)" "unprognostic (2.14e-1)" "unprognostic (1.51e-2)" "unprognostic (2.21e-1)" "unprognostic (3.22e-1)" "unprognostic (3.44e-2)" "unprognostic (6.29e-2)" "unprognostic (1.88e-1)" "unprognostic (5.14e-2)" "unprognostic (4.55e-3)" "unprognostic (1.48e-1)" "unprognostic (3.80e-1)" "unprognostic (3.46e-2)" "unprognostic (7.31e-2)" "unprognostic (3.66e-2)" "unprognostic (2.35e-1)" IL7R "CD127, IL7RA, lnc-IL7R" ENSG00000168685 "Interleukin 7 receptor" P16871 5 35852695-35879603 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes, Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 171.2" "Group enriched" "Detected in many" 5 "Innate lymphoid cells: 3240.4;T-cells: 1496.2" "Cell type enriched" "Detected in some" 115 "leukocyte: 454.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 102.3;MAIT T-cell: 370.2;memory CD4 T-cell: 214.4;memory CD8 T-cell: 151.1;naive CD4 T-cell: 180.0;naive CD8 T-cell: 125.1;NK-cell: 113.4" "Group enriched" "Detected in all" 34 "NK-cells: 113.4;T-cells: 370.2" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - T-cells, Colon - T-cells, Prostate - T-cells, Skin - T-cells, Stomach - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB010215, HPA067550, CAB080603" Supported Supported "Plasma membrane" "Intracellular and membrane" Receptor NA NA 290000 "Cluster 27: T-cells - Unknown function" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 9: T-cells - Adaptive immunity: Regulation" 13 "Plasma membrane" "CAB010215: , CAB080603: , HPA067550: " "unprognostic (2.81e-1)" "unprognostic (5.36e-3)" "unprognostic (4.45e-2)" "unprognostic (6.91e-2)" "unprognostic (9.97e-2)" "unprognostic (3.73e-1)" "unprognostic (3.58e-2)" "unprognostic (1.17e-2)" "unprognostic (2.53e-1)" "unprognostic (1.38e-1)" "unprognostic (1.25e-1)" "unprognostic (1.04e-2)" "unprognostic (1.22e-1)" "unprognostic (6.18e-3)" "unprognostic (2.22e-2)" "unprognostic (2.20e-3)" "unprognostic (6.89e-2)" "unprognostic (6.82e-2)" "unprognostic (1.79e-1)" "unprognostic (8.32e-3)" "unprognostic (2.31e-1)" "unprognostic (1.92e-1)" "unprognostic (1.94e-2)" "unprognostic (3.92e-1)" "unprognostic (1.72e-2)" "unprognostic (2.01e-1)" "unprognostic (1.22e-1)" "unprognostic (1.68e-2)" "unprognostic (2.03e-2)" "unprognostic (8.41e-2)" "unprognostic (5.78e-2)" IL9 "HP40, IL-9, P40" ENSG00000145839 "Interleukin 9" P15248 5 135892246-135895841 "Cancer-related genes, Predicted secreted proteins" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 7 "Platelets: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "lymphoma: 4.3" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" Interleukin NA NA 11000 "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 47: Platelets - Hemostasis" IL9R CD129 ENSG00000124334 "Interleukin 9 receptor" Q01113 X 155997696-156010817 "CD markers, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 3.1;urinary bladder: 4.0" "Cell type enhanced" "Detected in some" "Hematopoietic stem cells: 1.9;Innate lymphoid cells: 5.8;Mast cells: 14.6;Megakaryocyte-Erythroid progenitors: 1.9;NK-cells: 3.9;T-cells: 6.5;Thymocytes: 3.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder Urothelial Carcinoma (TCGA): 2.9" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "eosinophil: 3.5" "Group enriched" "Detected in many" 23 "B-cells: 1.9;granulocytes: 3.5;T-cells: 1.4" "Group enriched" "Detected in some" 7 "Leukemia: 18.3;lymphoma: 14.4" "Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA063240, HPA064557" Approved "Intracellular and membrane" Receptor NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" 4 "HPA063240: , HPA064557: " "unprognostic (1.04e-1)" "unprognostic (5.01e-2)" "unprognostic (6.34e-3)" "unprognostic (2.49e-1)" "unprognostic (8.56e-2)" "unprognostic (2.74e-1)" "unprognostic (7.09e-2)" ILDR1 "DFNB42, MGC50831" ENSG00000145103 "Immunoglobulin like domain containing receptor 1" Q86SU0 3 121987323-122022247 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 14.7" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 38.8;Cytotrophoblasts: 28.3;Epididymal principal cells: 26.7;Pituitary stem cells: 25.6;Respiratory secretory cells: 31.8;Salivary duct cells: 25.0" "Cell type enriched" "Detected in single" 4 "central nervous system macrophage: 2.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.7" "Lineage enriched" "Detected in single" 4 "B-cells: 1.7" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 12.4" "Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA018207 Approved "Intracellular and membrane" Receptor NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 33: Thyroid gland - Tissue development" "Cluster 48: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 38: Secretory epithelial cells - Exocrine secretion" "HPA018207: " "unprognostic (2.20e-2)" "unprognostic (4.23e-2)" "unprognostic (2.24e-1)" "unprognostic (6.39e-2)" "unprognostic (3.75e-1)" "unprognostic (9.06e-2)" "unprognostic (1.85e-1)" "unprognostic (9.73e-2)" "potential prognostic favorable (2.45e-6)" "unprognostic (3.43e-2)" "potential prognostic favorable (1.66e-4)" "unprognostic (1.25e-2)" "unprognostic (5.15e-2)" "unprognostic (7.42e-2)" "unprognostic (2.24e-1)" "unprognostic (3.79e-1)" "unprognostic (1.56e-1)" "unprognostic (2.64e-1)" "unprognostic (1.14e-1)" "unprognostic (5.72e-2)" "unprognostic (3.75e-2)" "unprognostic (1.47e-1)" "unprognostic (2.09e-2)" "unprognostic (9.55e-3)" "unprognostic (6.26e-3)" "unprognostic (2.01e-2)" "unprognostic (2.16e-2)" ILDR2 C1orf32 ENSG00000143195 "Immunoglobulin like domain containing receptor 2" Q71H61 1 166895711-166975540 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.0;retina: 9.8;testis: 8.2" "Cell type enhanced" "Detected in many" "Bergmann glia: 61.0;Brain excitatory neurons: 57.4;Cardiomyocytes: 128.8;Choroid plexus epithelial cells: 61.9;Corticotrophs: 59.5;Müller glia: 282.8;Oligodendrocyte progenitor cells: 184.2;Other brain neurons: 50.9;Podocytes: 98.3;Sertoli cells: 186.8;Thymocytes: 60.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 7.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 4.6" "Adipose visceral - Mesothelial cells, Prostate - Smooth muscle cells, Skin - Outer root sheath cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012545, HPA012815" Uncertain Approved "Plasma membrane" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 11: Muller glia cells - Retinal homeostasis" 1 "Plasma membrane" "HPA012545: , HPA012815: " "potential prognostic unfavorable (2.04e-4)" "unprognostic (2.43e-2)" "unprognostic (1.79e-2)" "potential prognostic favorable (1.54e-5)" "unprognostic (1.41e-2)" "unprognostic (1.63e-2)" "unprognostic (1.35e-1)" "unprognostic (4.27e-3)" "unprognostic (1.27e-1)" ILF2 NF45 ENSG00000143621 "Interleukin enhancer binding factor 2" Q12905 1 153661788-153671028 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 391.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007484, HPA072048" Supported Supported Nucleoplasm,Cytosol No No 1800000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 21: Non-specific - Metabolism" "Cluster 45: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 168 Nucleoplasm Cytosol "HPA007484: , HPA072048: " "unprognostic (1.10e-2)" "unprognostic (8.60e-3)" "unprognostic (2.19e-1)" "unprognostic (1.21e-1)" "unprognostic (2.24e-2)" "unprognostic (1.75e-2)" "unprognostic (3.87e-2)" "unprognostic (1.83e-2)" "unprognostic (3.11e-2)" "unprognostic (2.28e-3)" "unprognostic (2.40e-3)" "unprognostic (3.70e-1)" "unprognostic (1.43e-2)" "potential prognostic unfavorable (9.59e-5)" "unprognostic (3.91e-3)" "unprognostic (8.48e-2)" "unprognostic (2.91e-2)" "unprognostic (2.30e-1)" "unprognostic (2.43e-1)" "unprognostic (1.45e-2)" "unprognostic (2.06e-1)" "unprognostic (6.12e-3)" "unprognostic (1.19e-1)" "unprognostic (5.71e-2)" "unprognostic (4.54e-2)" "unprognostic (3.15e-2)" "unprognostic (7.30e-2)" "unprognostic (2.47e-1)" "unprognostic (2.41e-1)" "unprognostic (1.02e-1)" "unprognostic (3.35e-1)" ILF3 "DRBP76, MPHOSPH4, MPP4, MPP4110, NF110, NF110b, NF90, NF90a, NF90c, NF90ctv, NFAR-1, NFAR-2, NFAR110, NFAR90, TCP110" ENSG00000129351 "Interleukin enhancer binding factor 3" Q12906 19 10654304-10692400 "Cancer-related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Transcription, Transcription regulation" "DNA-binding, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001897 Supported Enhanced Nucleoplasm,Nucleoli,Mitochondria No No 2000000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 23: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 422 "Nucleoplasm, Nucleoli, Mitochondria" "HPA001897: " "unprognostic (1.73e-2)" "unprognostic (2.53e-1)" "unprognostic (8.14e-2)" "unprognostic (1.87e-3)" "unprognostic (2.88e-2)" "unprognostic (1.24e-1)" "unprognostic (2.14e-1)" "unprognostic (6.30e-3)" "unprognostic (4.18e-2)" "unprognostic (5.28e-3)" "potential prognostic favorable (8.93e-4)" "unprognostic (7.18e-2)" "unprognostic (1.29e-1)" "potential prognostic unfavorable (2.43e-4)" "unprognostic (1.39e-2)" "unprognostic (4.77e-3)" "unprognostic (1.27e-3)" "unprognostic (2.43e-1)" "unprognostic (4.94e-2)" "unprognostic (3.68e-2)" "unprognostic (5.52e-2)" "unprognostic (8.82e-2)" "unprognostic (7.75e-3)" "unprognostic (1.16e-1)" "unprognostic (4.30e-3)" "unprognostic (2.94e-2)" "unprognostic (1.22e-1)" "unprognostic (4.48e-2)" "unprognostic (3.46e-1)" "unprognostic (1.35e-2)" "unprognostic (7.41e-3)" ILK ENSG00000166333 "Integrin linked kinase" Q13418 11 6603708-6610874 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Megakaryocytes: 834.5;Platelets: 1249.4;Smooth muscle cells: 502.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004041, HPA048437" Enhanced Supported "Nucleoplasm,Actin filaments,Focal adhesion sites,Cytosol" NA NA 25000000 "Cluster 25: Non-specific - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 8: Immune cells - Immune response" "Cluster 24: Non-specific - Unknown function" "Cluster 62: Smooth muscle cells - Muscle contraction" 96 "Focal adhesion sites" "Nucleoplasm, Actin filaments, Cytosol" "CAB004041: , HPA048437: " "unprognostic (1.14e-1)" "unprognostic (6.63e-2)" "unprognostic (1.49e-3)" "unprognostic (5.84e-3)" "unprognostic (2.92e-1)" "unprognostic (4.23e-2)" "unprognostic (9.26e-2)" "unprognostic (1.40e-2)" "unprognostic (1.14e-2)" "unprognostic (7.84e-2)" "potential prognostic favorable (2.25e-7)" "unprognostic (1.08e-2)" "unprognostic (3.30e-2)" "potential prognostic unfavorable (7.44e-4)" "unprognostic (1.45e-1)" "unprognostic (1.22e-1)" "potential prognostic unfavorable (2.57e-4)" "unprognostic (2.07e-3)" "unprognostic (3.22e-3)" "unprognostic (4.45e-2)" "unprognostic (3.20e-3)" "unprognostic (1.01e-1)" "unprognostic (2.24e-1)" "unprognostic (1.27e-1)" "unprognostic (1.03e-2)" "unprognostic (2.09e-1)" "unprognostic (4.03e-2)" "unprognostic (4.28e-2)" "unprognostic (1.16e-1)" "unprognostic (1.76e-1)" "unprognostic (1.81e-1)" ILKAP "DKFZP434J2031, FLJ10181, PPM1O" ENSG00000132323 "ILK associated serine/threonine phosphatase" Q9H0C8 2 238170402-238203708 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004752 Uncertain NA NA 6500 "Cluster 5: Non-specific - Cell proliferation" "Cluster 24: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 35: RS4;11 - Unknown function" "Cluster 7: Non-specific - Transcription" 8 "HPA004752: " "unprognostic (3.42e-1)" "unprognostic (1.73e-1)" "unprognostic (1.41e-1)" "unprognostic (4.55e-1)" "unprognostic (1.46e-1)" "unprognostic (8.68e-2)" "unprognostic (2.31e-1)" "unprognostic (3.31e-2)" "unprognostic (2.43e-1)" "unprognostic (5.52e-3)" "unprognostic (2.27e-1)" "unprognostic (4.13e-2)" "unprognostic (2.66e-1)" "validated prognostic unfavorable (6.02e-6)" "validated prognostic unfavorable (6.13e-4)" "unprognostic (3.99e-2)" "unprognostic (5.92e-2)" "unprognostic (1.09e-1)" "unprognostic (3.73e-2)" "unprognostic (2.86e-2)" "unprognostic (2.13e-1)" "unprognostic (2.57e-3)" "potential prognostic unfavorable (4.28e-5)" "unprognostic (2.21e-1)" "unprognostic (4.61e-1)" "unprognostic (3.66e-1)" "unprognostic (2.63e-1)" "unprognostic (2.39e-1)" "unprognostic (1.19e-1)" "unprognostic (2.22e-3)" "unprognostic (8.04e-2)" ILRUN "C6orf106, dJ391O22.4, FLJ22195" ENSG00000196821 "Inflammation and lipid regulator with UBA-like and NBR1-like domains" Q9H6K1 6 34587288-34696859 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 202.1" "Cell type enhanced" "Detected in all" "Late spermatids: 596.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034489, HPA034490" Approved Supported "Nuclear speckles,Centrosome,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 3 "Nuclear speckles" "Centrosome, Cytosol" "HPA034489: , HPA034490: " "unprognostic (1.03e-2)" "unprognostic (3.93e-2)" "unprognostic (4.01e-2)" "unprognostic (2.51e-1)" "unprognostic (1.88e-3)" "unprognostic (1.07e-1)" "unprognostic (1.73e-1)" "unprognostic (1.61e-1)" "unprognostic (6.07e-2)" "validated prognostic favorable (3.75e-4)" "validated prognostic favorable (5.56e-5)" "unprognostic (1.15e-2)" "unprognostic (1.02e-1)" "unprognostic (1.67e-1)" "unprognostic (6.86e-2)" "unprognostic (3.00e-1)" "unprognostic (9.87e-3)" "unprognostic (7.50e-2)" "unprognostic (5.96e-3)" "unprognostic (9.10e-3)" "unprognostic (7.62e-2)" "unprognostic (1.19e-1)" "unprognostic (8.14e-2)" "unprognostic (1.64e-1)" "unprognostic (1.86e-2)" "unprognostic (1.88e-1)" "unprognostic (1.73e-1)" "unprognostic (5.64e-2)" "unprognostic (1.66e-1)" ILVBL "209L8, AHAS, FLJ39061, HACL1L, ILV2H, MGC1269, MGC19535" ENSG00000105135 "IlvB acetolactate synthase like" A1L0T0 19 15114984-15125786 "Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 113.3;Esophageal apical cells: 114.3;Extravillous trophoblasts: 202.3;Melanocytes: 148.0;Syncytiotrophoblasts: 366.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067682 Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 70: Non-specific - Protein processing" "Cluster 27: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." 14 "Golgi apparatus, Vesicles" "HPA067682: " "unprognostic (2.05e-2)" "unprognostic (1.22e-1)" "unprognostic (1.02e-1)" "unprognostic (3.38e-1)" "unprognostic (8.10e-2)" "unprognostic (2.53e-2)" "unprognostic (8.04e-3)" "unprognostic (4.46e-2)" "unprognostic (1.09e-1)" "unprognostic (8.85e-2)" "potential prognostic favorable (7.66e-15)" "unprognostic (2.60e-2)" "unprognostic (4.68e-3)" "unprognostic (4.69e-2)" "unprognostic (8.15e-2)" "unprognostic (2.65e-1)" "unprognostic (4.73e-2)" "unprognostic (2.49e-1)" "unprognostic (6.93e-2)" "unprognostic (4.27e-2)" "unprognostic (8.38e-3)" "unprognostic (3.78e-2)" "unprognostic (1.20e-1)" "unprognostic (1.04e-1)" "unprognostic (1.35e-3)" "unprognostic (4.61e-2)" "unprognostic (1.86e-1)" "unprognostic (7.76e-2)" "unprognostic (1.86e-1)" "unprognostic (2.08e-1)" "unprognostic (2.10e-1)" IMMP1L "FLJ25059, IMMP1" ENSG00000148950 "Inner mitochondrial membrane peptidase subunit 1" Q96LU5 11 31432401-31509645 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038372, HPA058308" Approved Enhanced Mitochondria NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 55: Myocytes - Oxidative muscle function" 5 Mitochondria "HPA038372: , HPA058308: " "unprognostic (1.27e-2)" "unprognostic (6.84e-2)" "unprognostic (1.87e-3)" "unprognostic (6.51e-3)" "unprognostic (5.68e-2)" "unprognostic (1.54e-1)" "unprognostic (1.97e-2)" "unprognostic (5.04e-3)" "unprognostic (5.45e-2)" "unprognostic (9.52e-3)" "unprognostic (4.13e-2)" "unprognostic (5.20e-3)" "unprognostic (1.55e-1)" "potential prognostic unfavorable (2.82e-6)" "unprognostic (1.28e-3)" "unprognostic (1.76e-1)" "unprognostic (3.97e-1)" "unprognostic (1.52e-1)" "unprognostic (3.90e-2)" "unprognostic (2.50e-2)" "unprognostic (7.99e-2)" "unprognostic (6.37e-3)" "unprognostic (3.38e-3)" "unprognostic (6.20e-2)" "unprognostic (7.54e-2)" "unprognostic (1.07e-1)" "unprognostic (2.75e-2)" "unprognostic (2.25e-2)" "unprognostic (1.99e-1)" "unprognostic (1.42e-1)" "unprognostic (6.18e-2)" IMMP2L "IMMP2L-IT1, IMP2" ENSG00000184903 "Inner mitochondrial membrane peptidase subunit 2" Q96T52 7 110662644-111562517 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pituicytes/FSCs: 1915.7;Renal connecting tubule cells: 2091.5;Retinal pigment epithelial cells: 2212.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026711 Approved Approved "Mitochondria,Flagellar centriole,Principal piece,End piece" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 76: Non-specific - Metabolism" "Cluster 33: Neurons - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 20 Mitochondria "Flagellar centriole, Principal piece, End piece" "HPA026711: " "unprognostic (7.41e-2)" "unprognostic (2.47e-2)" "unprognostic (2.05e-1)" "unprognostic (4.68e-2)" "unprognostic (1.08e-1)" "unprognostic (3.97e-2)" "unprognostic (1.10e-3)" "unprognostic (3.60e-1)" "unprognostic (6.78e-3)" "unprognostic (4.49e-2)" "potential prognostic favorable (3.01e-8)" "unprognostic (4.99e-2)" "unprognostic (6.94e-2)" "unprognostic (1.29e-2)" "unprognostic (6.15e-2)" "potential prognostic unfavorable (1.93e-4)" "unprognostic (6.84e-2)" "unprognostic (5.42e-2)" "unprognostic (7.28e-2)" "unprognostic (1.81e-2)" "unprognostic (1.66e-1)" "unprognostic (1.64e-1)" "unprognostic (1.09e-1)" "unprognostic (1.93e-2)" "unprognostic (1.30e-2)" "unprognostic (2.47e-2)" "unprognostic (3.18e-1)" "unprognostic (2.64e-3)" "unprognostic (1.46e-1)" "unprognostic (1.53e-1)" "unprognostic (1.91e-1)" IMMT "HMP, Mic60, MICOS60, MINOS2, P87, P89" ENSG00000132305 "Inner membrane mitochondrial protein" Q16891 2 86143932-86195472 "Essential proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 270.0" "Cell type enhanced" "Detected in all" "Oocytes: 290.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Minor Salivary Gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022439, HPA036164, HPA036165" Supported Enhanced Mitochondria NA NA 71000 "Cluster 13: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cellular respiration" "Cluster 23: Choroid plexus - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 97: Non-specific - Cellular respiration" 86 Mitochondria "CAB022439: , HPA036164: , HPA036165: " "unprognostic (9.84e-2)" "unprognostic (3.37e-3)" "unprognostic (1.10e-2)" "unprognostic (2.37e-1)" "unprognostic (9.03e-3)" "unprognostic (7.88e-2)" "unprognostic (1.56e-1)" "unprognostic (6.99e-2)" "unprognostic (7.83e-2)" "unprognostic (3.27e-3)" "potential prognostic favorable (1.39e-4)" "unprognostic (6.46e-2)" "unprognostic (5.84e-3)" "validated prognostic unfavorable (2.00e-6)" "validated prognostic unfavorable (1.10e-6)" "unprognostic (7.74e-3)" "unprognostic (7.39e-2)" "unprognostic (3.54e-2)" "unprognostic (1.10e-1)" "unprognostic (3.61e-2)" "unprognostic (3.20e-1)" "unprognostic (1.09e-1)" "unprognostic (1.26e-2)" "unprognostic (2.84e-1)" "unprognostic (2.59e-1)" "unprognostic (6.30e-2)" "unprognostic (1.12e-1)" "unprognostic (4.55e-2)" "unprognostic (4.16e-1)" "unprognostic (1.35e-1)" "unprognostic (1.66e-1)" IMP3 "BRMS2, C15orf12, FLJ10968, MRPS4" ENSG00000177971 "IMP U3 small nucleolar ribonucleoprotein 3" Q9NV31 15 75639085-75648706 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribosome biogenesis, rRNA processing" "Ribonucleoprotein, RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 353.4;Esophageal basal cells: 228.9;Esophageal suprabasal cells: 259.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA061177, HPA077989" Supported Nucleoplasm,Nucleoli,Cytosol No No "Cluster 3: Non-specific - Nuclear processes" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 58: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 67 Nucleoli "Nucleoplasm, Cytosol" "HPA061177: , HPA077989: " "unprognostic (1.62e-1)" "unprognostic (1.63e-1)" "unprognostic (1.63e-2)" "unprognostic (2.04e-1)" "unprognostic (1.59e-1)" "unprognostic (3.73e-1)" "unprognostic (3.79e-1)" "unprognostic (3.74e-2)" "unprognostic (1.73e-1)" "unprognostic (3.67e-2)" "potential prognostic favorable (1.04e-5)" "unprognostic (1.79e-3)" "unprognostic (1.73e-1)" "unprognostic (7.96e-2)" "unprognostic (1.55e-3)" "unprognostic (7.20e-2)" "unprognostic (1.54e-1)" "unprognostic (6.61e-2)" "unprognostic (9.80e-3)" "unprognostic (1.60e-1)" "unprognostic (1.30e-2)" "unprognostic (3.48e-1)" "unprognostic (1.92e-1)" "unprognostic (2.95e-1)" "unprognostic (2.81e-2)" "unprognostic (1.53e-1)" "unprognostic (7.81e-2)" "unprognostic (2.09e-2)" "unprognostic (2.83e-1)" "unprognostic (3.91e-1)" "unprognostic (1.26e-2)" IMP4 "BXDC4, MGC19606" ENSG00000136718 "IMP U3 small nucleolar ribonucleoprotein 4" Q96G21 2 130342877-130347967 "Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" Ribonucleoprotein "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 143.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066222, HPA066673" Enhanced Nucleoli NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 24: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 17: Non-specific - RNA processing" 36 Nucleoli "HPA066222: , HPA066673: " "unprognostic (9.23e-3)" "unprognostic (1.57e-2)" "unprognostic (4.30e-1)" "unprognostic (1.80e-2)" "unprognostic (1.14e-2)" "unprognostic (2.66e-1)" "unprognostic (9.57e-2)" "unprognostic (5.63e-1)" "unprognostic (2.60e-3)" "unprognostic (4.40e-2)" "unprognostic (2.72e-2)" "unprognostic (2.21e-2)" "unprognostic (3.75e-2)" "unprognostic (1.38e-2)" "potential prognostic unfavorable (7.17e-6)" "unprognostic (1.37e-3)" "unprognostic (8.55e-2)" "unprognostic (8.67e-2)" "unprognostic (2.29e-1)" "unprognostic (5.45e-2)" "unprognostic (2.42e-1)" "unprognostic (4.90e-3)" "unprognostic (3.30e-1)" "unprognostic (3.32e-2)" "unprognostic (2.77e-1)" "unprognostic (1.40e-1)" "unprognostic (1.29e-1)" "unprognostic (1.72e-1)" "unprognostic (3.86e-1)" "unprognostic (1.99e-1)" "unprognostic (3.17e-1)" IMPA1 IMPA ENSG00000133731 "Inositol monophosphatase 1" P29218 8 81656914-81686331 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037489, HPA037490" Approved Uncertain "Vesicles,Actin filaments" NA No 370000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 14: Neurons - Synaptic function" "Cluster 40: Non-specific - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 7 "Actin filaments" Vesicles "HPA037489: , HPA037490: " "unprognostic (5.74e-2)" "unprognostic (1.05e-1)" "unprognostic (1.43e-3)" "potential prognostic unfavorable (5.85e-4)" "unprognostic (1.67e-2)" "unprognostic (8.63e-2)" "unprognostic (1.16e-1)" "unprognostic (2.50e-1)" "unprognostic (6.01e-2)" "potential prognostic unfavorable (8.04e-4)" "potential prognostic favorable (7.24e-4)" "unprognostic (2.07e-2)" "unprognostic (2.07e-1)" "unprognostic (4.21e-1)" "unprognostic (8.27e-2)" "unprognostic (1.52e-2)" "unprognostic (1.02e-1)" "unprognostic (7.68e-2)" "unprognostic (9.08e-3)" "potential prognostic unfavorable (2.68e-4)" "unprognostic (2.29e-2)" "unprognostic (6.89e-3)" "unprognostic (9.21e-3)" "unprognostic (1.39e-1)" "unprognostic (1.20e-1)" "unprognostic (4.68e-2)" "unprognostic (2.03e-1)" "unprognostic (1.52e-1)" "unprognostic (1.98e-1)" "unprognostic (2.02e-1)" "unprognostic (3.51e-1)" IMPA2 ENSG00000141401 "Inositol monophosphatase 2" O14732 18 11981025-12030877 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 338.5;skeletal muscle: 260.2" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 379.7;Esophageal basal cells: 477.5;Esophageal suprabasal cells: 407.8;Extravillous trophoblasts: 378.0;Pancreatic acinar cells: 884.7;Suprabasal keratinocytes: 243.9" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 25.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 26.0;neutrophil: 31.5" "Group enriched" "Detected in many" 11 "dendritic cells: 9.0;granulocytes: 31.5;monocytes: 11.4" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029561 Approved Approved Nucleoplasm,Mitochondria Yes No "Cluster 7: Non-specific - Innate immune response" "Cluster 24: Non-specific - Transcription" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 85: Squamous epithelial cells - Keratinization" 6 Nucleoplasm Mitochondria "HPA029561: " "unprognostic (1.90e-1)" "unprognostic (1.48e-1)" "unprognostic (1.24e-1)" "unprognostic (1.16e-1)" "unprognostic (1.17e-2)" "unprognostic (9.91e-2)" "unprognostic (8.36e-3)" "unprognostic (6.55e-3)" "unprognostic (4.64e-2)" "unprognostic (1.17e-1)" "validated prognostic favorable (1.64e-13)" "validated prognostic favorable (9.85e-5)" "potential prognostic favorable (2.96e-5)" "unprognostic (1.07e-3)" "potential prognostic unfavorable (1.78e-5)" "unprognostic (3.25e-1)" "unprognostic (1.62e-2)" "unprognostic (2.12e-1)" "unprognostic (1.04e-1)" "unprognostic (6.66e-2)" "unprognostic (1.67e-1)" "unprognostic (9.60e-3)" "unprognostic (1.22e-1)" "unprognostic (1.74e-2)" "unprognostic (1.06e-1)" "unprognostic (4.67e-2)" "unprognostic (1.40e-1)" "unprognostic (2.58e-1)" "unprognostic (5.47e-2)" "unprognostic (2.34e-3)" "unprognostic (3.52e-1)" IMPACT RWDD5 ENSG00000154059 "Impact RWD domain protein" Q9P2X3 18 24426634-24453531 "Predicted intracellular proteins" "Differentiation, Neurogenesis, Stress response, Translation regulation" "Actin-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 95.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 66.2" "Lineage enriched" "Detected in all" 5 "granulocytes: 66.2" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041045, HPA041968" Approved Approved Nucleoplasm NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 61: Non-specific - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 13: Non-specific - Mixed function" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 2 Nucleoplasm "HPA041045: , HPA041968: " "unprognostic (2.98e-1)" "unprognostic (3.02e-1)" "unprognostic (2.05e-1)" "unprognostic (5.92e-3)" "unprognostic (3.84e-2)" "unprognostic (1.41e-1)" "unprognostic (1.62e-1)" "unprognostic (3.55e-2)" "unprognostic (6.50e-2)" "unprognostic (6.21e-3)" "potential prognostic favorable (1.26e-7)" "unprognostic (3.76e-3)" "unprognostic (2.90e-3)" "unprognostic (2.21e-2)" "unprognostic (7.84e-2)" "unprognostic (8.76e-2)" "unprognostic (1.54e-1)" "unprognostic (2.73e-1)" "unprognostic (4.66e-2)" "unprognostic (2.93e-1)" "unprognostic (2.18e-2)" "unprognostic (4.30e-2)" "unprognostic (1.15e-1)" "unprognostic (1.13e-1)" "unprognostic (5.83e-2)" "unprognostic (2.24e-1)" "unprognostic (1.15e-1)" "unprognostic (3.27e-3)" "unprognostic (1.45e-1)" "unprognostic (2.98e-2)" "unprognostic (3.12e-1)" IMPDH1 "LCA11, RP10, sWSS2608" ENSG00000106348 "Inosine monophosphate dehydrogenase 1" P20839 7 128392277-128410252 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "GMP biosynthesis, Purine biosynthesis" "DNA-binding, Oxidoreductase, RNA-binding" "Disease variant, FDA approved drug targets, Leber congenital amaurosis, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 98.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 89.0;monocytes: 64.6;Neutrophils: 146.0;Retinal bipolar cells: 113.1;Retinal horizontal cells: 74.1;Rod photoreceptor cells: 117.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 89.2;eosinophil: 89.3;intermediate monocyte: 104.6;myeloid DC: 60.0;neutrophil: 198.3;non-classical monocyte: 136.7" "Group enriched" "Detected in all" 5 "dendritic cells: 60.0;granulocytes: 198.3;monocytes: 136.7" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Macrophages, Pituitary gland - Gonadotropes, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001400 Approved Supported "Cytosol,Rods & Rings" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 4 "Cytosol, Rods & Rings" "HPA001400: " "unprognostic (1.05e-3)" "unprognostic (1.83e-2)" "unprognostic (3.79e-1)" "unprognostic (2.27e-3)" "unprognostic (1.00e-2)" "unprognostic (1.10e-1)" "unprognostic (1.14e-3)" "unprognostic (2.16e-2)" "unprognostic (1.87e-1)" "unprognostic (3.04e-2)" "validated prognostic unfavorable (2.02e-5)" "validated prognostic unfavorable (1.09e-4)" "unprognostic (3.12e-3)" "potential prognostic unfavorable (2.75e-8)" "unprognostic (3.46e-2)" "unprognostic (1.55e-1)" "unprognostic (1.30e-3)" "unprognostic (5.22e-2)" "unprognostic (9.50e-2)" "unprognostic (3.77e-2)" "unprognostic (1.10e-2)" "unprognostic (6.14e-2)" "unprognostic (4.74e-2)" "unprognostic (3.20e-2)" "unprognostic (2.89e-1)" "unprognostic (4.40e-1)" "unprognostic (8.84e-2)" "unprognostic (3.50e-1)" "unprognostic (2.40e-1)" "unprognostic (1.37e-2)" "unprognostic (1.76e-1)" IMPDH2 ENSG00000178035 "Inosine monophosphate dehydrogenase 2" P12268 3 49024325-49029447 "Enzymes, Essential proteins, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "GMP biosynthesis, Purine biosynthesis" "DNA-binding, Oxidoreductase, RNA-binding" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 36.5;Enteric stem cells: 139.6;Enteric transient amplifying cells: 105.8;Epididymal basal cells: 46.4;Epididymal efferent duct absorptive cells: 52.6;Gastric chief cells: 44.8;Paneth cells: 139.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001400, CAB020717" Approved Supported "Cytosol,Rods & Rings" NA NA 290000 "Cluster 18: Non-specific - Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 27: Non-specific - Mixed function" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 40 Cytosol "Rods & Rings" "CAB020717: , HPA001400: " "unprognostic (1.39e-2)" "unprognostic (1.76e-1)" "unprognostic (8.39e-2)" "unprognostic (1.67e-2)" "unprognostic (4.55e-3)" "unprognostic (3.85e-1)" "unprognostic (1.73e-3)" "unprognostic (2.04e-3)" "unprognostic (1.03e-2)" "potential prognostic unfavorable (1.23e-4)" "potential prognostic favorable (4.86e-5)" "unprognostic (1.44e-2)" "unprognostic (4.19e-1)" "validated prognostic unfavorable (7.42e-5)" "validated prognostic unfavorable (4.15e-4)" "unprognostic (2.00e-1)" "potential prognostic unfavorable (2.78e-4)" "unprognostic (1.33e-1)" "unprognostic (6.53e-2)" "unprognostic (3.40e-2)" "unprognostic (8.28e-3)" "unprognostic (4.72e-3)" "unprognostic (5.49e-3)" "unprognostic (1.34e-2)" "unprognostic (3.14e-3)" "unprognostic (8.54e-2)" "unprognostic (1.54e-1)" "unprognostic (1.75e-1)" "unprognostic (1.92e-1)" "unprognostic (5.28e-2)" "unprognostic (3.46e-2)" IMPG1 "GP147, IPM150, SPACR" ENSG00000112706 "Interphotoreceptor matrix proteoglycan 1" Q17R60 6 75921114-76072678 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Heparin-binding, Receptor" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 93 "retina: 621.3" "Group enriched" "Detected in some" 23 "Cone photoreceptor cells: 1053.7;Rod photoreceptor cells: 1299.2" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "prostate cancer: 2.0" "Minor Salivary Gland - Minor salivary glandular cells" "Region enriched" "Detected in single" 4 "basal ganglia: 3.3" "Low region specificity" "Detected in many" "HPA027142, HPA030332, HPA030333" Enhanced Uncertain "Plasma membrane,Microtubules,Mid piece,Principal piece,End piece" "Secreted in other tissues" Receptor NA NA "Cluster 42: Retina - Visual perception" "Cluster 34: Non-specific - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 79: Photoreceptor cells - Phototransduction" "Plasma membrane, Microtubules, Mid piece, Principal piece, End piece" "HPA027142: , HPA030332: , HPA030333: " "unprognostic (1.38e-1)" IMPG2 "IPM200, RP56, SPACRCAN" ENSG00000081148 "Interphotoreceptor matrix proteoglycan 2" Q9BZV3 3 101222546-101320575 "Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Heparin-binding, Receptor" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 31 "retina: 282.9" "Group enriched" "Detected in many" 20 "Cone photoreceptor cells: 724.5;Rod photoreceptor cells: 741.3" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in single" 13 "Ovary Serous Cystadenocarcinoma (TCGA): 3.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Brain cancer: 2.3;lung cancer: 1.2;ovarian cancer: 2.2;Uterine cancer: 3.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA008779, HPA015907" Enhanced "Secreted in other tissues" Receptor NA NA "Cluster 42: Retina - Visual perception" "Cluster 44: Non-specific - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 79: Photoreceptor cells - Phototransduction" "HPA008779: , HPA015907: " "unprognostic (4.16e-2)" "unprognostic (5.77e-2)" "unprognostic (1.33e-1)" "unprognostic (1.56e-2)" INA "NEF5, NF-66" ENSG00000148798 "Internexin neuronal intermediate filament protein alpha" Q16352 10 103277138-103290346 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 116.7;pituitary gland: 38.6;retina: 90.1" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 47.9;Brain inhibitory neurons: 54.3;Cone photoreceptor cells: 51.8;Corticotrophs: 60.8;Early spermatids: 35.3;Gonadotrophs: 43.7;Lactotrophs: 36.8;Late primary spermatocytes: 46.5;Late spermatids: 37.7;Other brain neurons: 78.0;Pancreatic islet cells: 66.9;Retinal amacrine cells: 30.4;Retinal bipolar cells: 49.3;Retinal ganglion cells: 42.5;Retinal horizontal cells: 38.1;Rod photoreceptor cells: 39.1;Thyrotrophs: 25.5" "Cell type enhanced" "Detected in all" "mammillary body: 160.5" "Group enriched" "Detected in many" 5 "Bladder Urothelial Carcinoma (TCGA): 22.9;Glioblastoma Multiforme (TCGA): 7.8;Testicular Germ Cell Tumor (TCGA): 29.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 58.9;Neuroblastoma: 66.0" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Pituitary gland - Lactotropes, Stomach - Gastric enteroendocrine cells, Testis - Early spermatids, Thyroid gland - Parafollicular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002059, HPA007572, HPA008057" Enhanced Supported Approved "Intermediate filaments,Cytosol" NA NA 600000 "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 15 "Intermediate filaments" Cytosol "CAB002059: , HPA007572: , HPA008057: " "unprognostic (6.16e-2)" "unprognostic (2.65e-1)" "potential prognostic favorable (2.37e-4)" "unprognostic (3.20e-1)" "potential prognostic favorable (2.78e-4)" "unprognostic (2.02e-3)" "unprognostic (1.87e-2)" "unprognostic (7.18e-3)" "unprognostic (8.36e-2)" "unprognostic (1.59e-2)" "unprognostic (7.23e-2)" "unprognostic (2.81e-1)" "unprognostic (1.92e-1)" "unprognostic (1.63e-1)" "unprognostic (9.59e-3)" "unprognostic (5.43e-2)" "unprognostic (1.82e-1)" "unprognostic (4.13e-2)" INAFM1 PRR24 ENSG00000257704 "InaF motif containing 1" C9JVW0 19 47274885-47275723 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 76.6;Endometrial stromal cells: 66.8;Hepatic stellate cells: 58.1;Pericytes: 63.4;Vascular smooth muscle cells: 64.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 58.9" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" HPA064015 Uncertain NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 1: Neurons - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 110: Mural cells - ECM organization" "HPA064015: " "unprognostic (2.51e-3)" "unprognostic (4.61e-2)" "unprognostic (2.07e-1)" "potential prognostic unfavorable (1.58e-4)" "unprognostic (1.82e-2)" "unprognostic (2.51e-1)" "unprognostic (1.64e-1)" "unprognostic (2.53e-3)" "unprognostic (2.99e-1)" "potential prognostic unfavorable (1.25e-4)" "unprognostic (7.08e-2)" "unprognostic (5.95e-2)" "unprognostic (1.11e-1)" "unprognostic (1.58e-1)" "unprognostic (1.60e-1)" "unprognostic (1.87e-1)" "unprognostic (3.83e-1)" "unprognostic (2.44e-2)" "unprognostic (2.08e-3)" "unprognostic (1.23e-1)" "unprognostic (5.04e-1)" "unprognostic (1.41e-1)" "unprognostic (2.52e-2)" "unprognostic (5.11e-2)" "unprognostic (1.09e-2)" "unprognostic (1.61e-2)" "unprognostic (1.61e-1)" "unprognostic (1.73e-1)" "unprognostic (1.59e-1)" INAFM2 "LINC00984, OGU1" ENSG00000259330 "InaF motif containing 2" P0DMQ5 15 40323692-40326715 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Platelets: 385.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 2.7" "Group enriched" "Detected in many" 4 "dendritic cells: 1.1;granulocytes: 2.7;monocytes: 1.1" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 85000 "Cluster 29: Non-specific - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 47: Platelets - Hemostasis" "unprognostic (2.88e-1)" "unprognostic (2.35e-3)" "unprognostic (9.22e-2)" "unprognostic (7.55e-2)" "unprognostic (1.20e-1)" "unprognostic (3.15e-2)" "unprognostic (3.73e-2)" "unprognostic (8.40e-3)" "unprognostic (9.15e-3)" "unprognostic (5.67e-2)" "unprognostic (2.78e-2)" "unprognostic (4.81e-1)" "unprognostic (1.39e-1)" "potential prognostic favorable (1.90e-4)" "unprognostic (3.08e-1)" "unprognostic (1.52e-1)" "unprognostic (1.69e-1)" "unprognostic (3.72e-3)" "unprognostic (3.33e-2)" "unprognostic (1.72e-2)" "unprognostic (6.86e-2)" "unprognostic (2.04e-1)" "potential prognostic unfavorable (2.16e-4)" "unprognostic (5.76e-2)" "unprognostic (1.70e-1)" "unprognostic (7.06e-3)" "unprognostic (6.26e-2)" "unprognostic (6.26e-2)" "unprognostic (3.57e-3)" INAVA "C1orf106, FLJ10901" ENSG00000163362 "Innate immunity activator" Q3KP66 1 200891048-200915742 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 41.7;intestine: 52.2;skin 1: 44.1" "Cell type enhanced" "Detected in many" "Colonocytes: 112.7;Enteric transient amplifying cells: 57.4;Enterocytes: 212.0;Esophageal apical cells: 61.7;Foveolar cells: 78.4;Goblet cells: 92.5;Paneth cells: 73.5;Prostatic hillock cells: 96.9;Urothelial cells: 69.9" "Group enriched" "Detected in some" 8 "committed oligodendrocyte precursor: 37.0;oligodendrocyte precursor cell: 14.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Liver - Cholangiocytes, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA027499, HPA027511, HPA079622" Uncertain Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 77: Intestine - Digestion" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 1: Enterocytes - Absorption and Digestion" 27 Nucleoplasm "Nuclear bodies" "HPA027499: , HPA027511: , HPA079622: " "unprognostic (2.14e-2)" "unprognostic (3.41e-2)" "unprognostic (8.84e-3)" "unprognostic (3.83e-2)" "unprognostic (5.85e-2)" "unprognostic (1.24e-1)" "unprognostic (2.47e-2)" "unprognostic (1.21e-1)" "potential prognostic favorable (1.50e-6)" "unprognostic (1.14e-1)" "unprognostic (8.21e-2)" "unprognostic (2.71e-2)" "unprognostic (1.06e-2)" "unprognostic (8.71e-2)" "unprognostic (3.27e-2)" "unprognostic (2.07e-2)" "unprognostic (2.73e-1)" "unprognostic (3.78e-2)" "unprognostic (5.19e-3)" "unprognostic (6.04e-2)" "unprognostic (2.66e-1)" "unprognostic (4.83e-2)" "unprognostic (1.07e-1)" "unprognostic (1.06e-1)" "unprognostic (1.24e-1)" "unprognostic (1.07e-1)" "unprognostic (2.86e-1)" "potential prognostic unfavorable (6.15e-4)" INCA1 ENSG00000196388 "Inhibitor of CDK, cyclin A1 interacting protein 1" Q0VD86 17 4988130-4997610 "Predicted intracellular proteins" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 46.1" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 254.0;Early spermatids: 121.7;Late primary spermatocytes: 87.5;Late spermatids: 512.8;Undifferentiated spermatogonia: 38.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044359, HPA052401" Uncertain Approved "Nucleoplasm,Nuclear bodies" No No "Cluster 33: Non-specific - ATP binding" "Cluster 47: Testis - Mixed function" "Cluster 45: Non-specific - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 3: Early primary spermatocytes - Early meiosis" 224 "Nucleoplasm, Nuclear bodies" "HPA044359: , HPA052401: " "unprognostic (1.22e-2)" "unprognostic (6.81e-2)" "unprognostic (8.49e-2)" "unprognostic (3.48e-3)" "unprognostic (4.83e-3)" "unprognostic (1.91e-1)" "unprognostic (2.90e-3)" "unprognostic (8.96e-2)" "unprognostic (1.65e-2)" "potential prognostic unfavorable (6.20e-4)" "unprognostic (1.05e-2)" "unprognostic (2.06e-1)" "unprognostic (1.09e-2)" "unprognostic (2.09e-2)" "unprognostic (2.66e-2)" "unprognostic (1.48e-2)" "unprognostic (2.02e-1)" "unprognostic (1.35e-1)" "unprognostic (1.53e-1)" "unprognostic (3.07e-1)" "unprognostic (1.34e-2)" "potential prognostic favorable (7.60e-4)" "unprognostic (1.23e-1)" "unprognostic (1.42e-2)" "unprognostic (4.23e-2)" "unprognostic (2.04e-1)" "unprognostic (5.64e-2)" "unprognostic (1.95e-1)" "unprognostic (2.11e-2)" "unprognostic (1.42e-1)" INCENP FLJ31633 ENSG00000149503 "Inner centromere protein" Q9NQS7 11 62123998-62153169 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 19.8" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 41.0;Esophageal apical cells: 40.8;Megakaryocyte progenitors: 38.8;Monocyte progenitors: 79.6;Neutrophil progenitors: 30.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "basophil: 1.2;NK-cell: 1.1" "Group enriched" "Detected in many" 7 "granulocytes: 1.2;NK-cells: 1.1" "Low cancer specificity" "Detected in all" "Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013292, HPA051339, HPA070550" Enhanced Supported "Nucleoplasm,Nuclear bodies,Kinetochore,Midbody" Yes Yes "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 15: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 32 "Nuclear bodies, Kinetochore" "Nucleoplasm, Midbody" "CAB013292: , HPA051339: , HPA070550: " "unprognostic (1.70e-1)" "unprognostic (2.10e-1)" "unprognostic (1.38e-1)" "unprognostic (4.90e-3)" "unprognostic (7.12e-2)" "unprognostic (2.06e-1)" "unprognostic (3.20e-1)" "unprognostic (5.84e-2)" "unprognostic (2.97e-1)" "potential prognostic unfavorable (6.69e-5)" "unprognostic (1.28e-3)" "unprognostic (1.96e-1)" "unprognostic (3.31e-2)" "validated prognostic unfavorable (1.49e-4)" "validated prognostic unfavorable (2.27e-4)" "unprognostic (1.17e-3)" "potential prognostic unfavorable (1.82e-4)" "unprognostic (1.56e-1)" "unprognostic (4.17e-2)" "unprognostic (1.78e-1)" "unprognostic (7.34e-2)" "potential prognostic unfavorable (1.67e-5)" "unprognostic (2.34e-2)" "unprognostic (8.67e-2)" "unprognostic (1.22e-2)" "unprognostic (1.40e-1)" "unprognostic (9.51e-2)" "unprognostic (1.38e-2)" "unprognostic (1.72e-1)" "unprognostic (7.55e-2)" "unprognostic (1.22e-1)" INF2 "C14orf151, C14orf173, MGC13251" ENSG00000203485 "Inverted formin 2" Q27J81 14 104681146-104722535 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 157.5;Extravillous trophoblasts: 126.9;Foveolar cells: 200.6;Megakaryocytes: 111.3;Oligodendrocytes: 126.5;Platelets: 435.7;Podocytes: 147.9" "Cell type enhanced" "Detected in all" "oligodendrocyte: 154.0;vascular associated smooth muscle cell: 125.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Stomach - Gastric mucous cells, Testis - Sertoli cells" "Region enhanced" "Detected in all" "basal ganglia: 224.2" HPA000724 Approved Approved "Nuclear bodies,Endoplasmic reticulum" NA NA 1400000 "Cluster 13: Non-specific - Mitochondria" "Cluster 74: Non-specific - Signal transduction" "Cluster 11: White matter - Signal transduction" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 68: Foveolar cells - Mucosal defense" 19 "Endoplasmic reticulum" "Nuclear bodies" "HPA000724: " "unprognostic (1.26e-1)" "unprognostic (5.24e-2)" "unprognostic (2.29e-2)" "unprognostic (1.02e-2)" "unprognostic (5.30e-2)" "unprognostic (2.86e-1)" "unprognostic (1.15e-2)" "unprognostic (1.15e-1)" "unprognostic (7.37e-2)" "unprognostic (1.30e-2)" "unprognostic (3.00e-2)" "unprognostic (2.49e-3)" "unprognostic (2.98e-2)" "potential prognostic unfavorable (1.26e-7)" "unprognostic (8.40e-2)" "unprognostic (3.66e-2)" "unprognostic (9.08e-2)" "unprognostic (8.39e-2)" "unprognostic (1.15e-1)" "unprognostic (2.53e-3)" "unprognostic (1.26e-1)" "unprognostic (9.60e-2)" "unprognostic (7.14e-3)" "unprognostic (4.73e-2)" "unprognostic (3.09e-2)" "unprognostic (9.80e-2)" "unprognostic (1.97e-2)" "unprognostic (3.54e-1)" "unprognostic (1.48e-1)" "unprognostic (2.12e-1)" "unprognostic (1.09e-2)" ING1 "p24ING1c, p33, p33ING1, p33ING1b, p47, p47ING1a" ENSG00000153487 "Inhibitor of growth family member 1" Q9UK53 13 110712736-110723339 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 267.1;Extravillous trophoblasts: 109.7;Late primary spermatocytes: 111.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016136, CAB017773, HPA052591" Approved Approved "Nucleoplasm,Endoplasmic reticulum,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 67: Testis - Mixed function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 19: Non-specific - Unknown function" "Cluster 20: Non-specific - Transcription regulation" 28 Nucleoplasm "Endoplasmic reticulum, Cytosol" "CAB016136: , CAB017773: , HPA052591: " "unprognostic (3.25e-2)" "unprognostic (9.28e-3)" "unprognostic (1.91e-1)" "unprognostic (9.44e-2)" "unprognostic (4.89e-2)" "unprognostic (5.12e-3)" "unprognostic (8.44e-2)" "unprognostic (1.68e-1)" "unprognostic (1.10e-1)" "unprognostic (2.21e-2)" "unprognostic (4.96e-3)" "unprognostic (8.06e-3)" "unprognostic (5.84e-2)" "unprognostic (5.71e-3)" "unprognostic (3.61e-2)" "unprognostic (1.54e-1)" "unprognostic (3.44e-2)" "unprognostic (2.64e-1)" "unprognostic (1.95e-1)" "unprognostic (1.55e-1)" "unprognostic (3.57e-1)" "unprognostic (2.56e-2)" "unprognostic (1.39e-1)" "unprognostic (3.01e-1)" "unprognostic (1.26e-1)" "unprognostic (2.29e-1)" "unprognostic (1.21e-1)" "unprognostic (1.01e-2)" "unprognostic (1.70e-1)" "unprognostic (1.32e-2)" "unprognostic (6.43e-3)" ING2 "ING1L, p33ING2" ENSG00000168556 "Inhibitor of growth family member 2" Q9H160 4 183505058-183512429 "Predicted intracellular proteins" "Growth regulation, Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal efferent duct ciliated cells: 162.4;Esophageal apical cells: 145.8;Extravillous trophoblasts: 128.3;Granulosa cells: 159.0;Late primary spermatocytes: 155.0;Ovarian stromal cells: 146.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019486, HPA021517" Supported Supported Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 75: Ovary - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 94: Gonadal somatic cells - Mixed function" 51 Nucleoplasm "HPA019486: , HPA021517: " "unprognostic (2.56e-1)" "unprognostic (9.74e-2)" "unprognostic (5.40e-2)" "unprognostic (1.95e-1)" "unprognostic (8.44e-2)" "unprognostic (3.59e-2)" "unprognostic (6.05e-2)" "unprognostic (4.82e-3)" "unprognostic (8.27e-2)" "unprognostic (1.10e-1)" "potential prognostic favorable (2.14e-5)" "unprognostic (6.20e-3)" "unprognostic (1.17e-2)" "unprognostic (3.18e-3)" "unprognostic (1.28e-2)" "potential prognostic unfavorable (4.14e-5)" "unprognostic (2.89e-2)" "unprognostic (1.09e-1)" "unprognostic (7.22e-2)" "unprognostic (1.49e-1)" "unprognostic (6.95e-2)" "unprognostic (1.22e-1)" "unprognostic (1.51e-2)" "unprognostic (2.78e-2)" "unprognostic (1.26e-1)" "unprognostic (5.86e-2)" "unprognostic (1.04e-1)" "unprognostic (1.64e-1)" "unprognostic (1.67e-1)" "unprognostic (3.74e-1)" "unprognostic (1.40e-1)" ING3 "Eaf4, FLJ20089, MEAF4, p47ING3" ENSG00000071243 "Inhibitor of growth family member 3" Q9NXR8 7 120950763-120977216 "Disease related genes, Predicted intracellular proteins" "Growth regulation, Transcription, Transcription regulation" "Chromatin regulator" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "bone marrow: 76.0" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004762, HPA067388, HPA067575" Uncertain Enhanced Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 15: Bone marrow - Innate immune response" "Cluster 35: Non-specific - DNA binding" "Cluster 39: Non-specific - Transcription" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 30 Nucleoplasm "HPA004762: , HPA067388: , HPA067575: " "potential prognostic favorable (5.40e-4)" "unprognostic (1.78e-1)" "unprognostic (5.56e-2)" "unprognostic (1.03e-1)" "unprognostic (3.33e-1)" "unprognostic (1.01e-1)" "unprognostic (1.24e-1)" "unprognostic (2.41e-2)" "unprognostic (7.57e-2)" "unprognostic (8.66e-2)" "validated prognostic favorable (1.78e-8)" "validated prognostic favorable (1.35e-4)" "unprognostic (3.04e-1)" "unprognostic (1.23e-1)" "unprognostic (1.72e-1)" "unprognostic (5.40e-2)" "unprognostic (2.90e-2)" "unprognostic (2.41e-1)" "unprognostic (1.26e-1)" "unprognostic (8.33e-2)" "unprognostic (3.13e-1)" "unprognostic (2.04e-1)" "unprognostic (1.74e-1)" "unprognostic (2.01e-1)" "unprognostic (5.79e-2)" "unprognostic (9.25e-3)" "unprognostic (1.17e-1)" "unprognostic (2.43e-1)" "unprognostic (6.54e-2)" "unprognostic (2.22e-1)" "unprognostic (3.31e-1)" ING4 "my036, p29ING4" ENSG00000111653 "Inhibitor of growth family member 4" Q9UNL4 12 6650301-6663142 "Predicted intracellular proteins" "Apoptosis, Cell cycle" "Chromatin regulator" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Platelets: 126.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031817, HPA057338" Approved Supported Nucleoplasm Yes No "Cluster 42: Non-specific - Vesicular transport" "Cluster 64: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 36 Nucleoplasm "HPA031817: , HPA057338: " "unprognostic (1.11e-1)" "unprognostic (8.72e-2)" "unprognostic (2.42e-1)" "unprognostic (3.24e-2)" "unprognostic (2.90e-2)" "unprognostic (2.59e-1)" "unprognostic (1.77e-1)" "unprognostic (1.83e-2)" "unprognostic (1.69e-2)" "unprognostic (1.11e-1)" "unprognostic (4.59e-3)" "unprognostic (2.14e-2)" "potential prognostic favorable (3.36e-4)" "unprognostic (3.09e-3)" "unprognostic (7.10e-2)" "unprognostic (3.64e-2)" "unprognostic (1.74e-1)" "unprognostic (3.95e-2)" "unprognostic (2.14e-1)" "unprognostic (9.14e-2)" "unprognostic (6.80e-2)" "unprognostic (2.07e-1)" "unprognostic (7.14e-3)" "unprognostic (7.62e-2)" "unprognostic (1.63e-3)" "unprognostic (2.30e-1)" "unprognostic (6.96e-3)" "unprognostic (1.26e-1)" "unprognostic (1.22e-1)" "unprognostic (5.07e-1)" "unprognostic (9.40e-2)" ING5 "FLJ23842, p28ING5" ENSG00000168395 "Inhibitor of growth family member 5" Q8WYH8 2 241687085-241729478 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 21.4" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042685 Approved NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 89: Adipocytes - Lipid metabolism" 50 "HPA042685: " "potential prognostic favorable (4.83e-4)" "unprognostic (4.26e-1)" "potential prognostic favorable (2.26e-4)" "unprognostic (6.18e-2)" "unprognostic (7.53e-3)" "unprognostic (4.52e-1)" "unprognostic (1.26e-1)" "unprognostic (1.77e-1)" "unprognostic (6.49e-3)" "unprognostic (1.30e-1)" "unprognostic (1.00e-1)" "unprognostic (2.16e-2)" "unprognostic (3.59e-1)" "potential prognostic unfavorable (1.93e-7)" "unprognostic (6.03e-3)" "unprognostic (2.20e-1)" "unprognostic (2.48e-1)" "unprognostic (6.78e-2)" "potential prognostic favorable (4.83e-4)" "unprognostic (5.58e-2)" "unprognostic (9.57e-2)" "unprognostic (1.92e-3)" "unprognostic (9.25e-3)" "unprognostic (1.30e-1)" "unprognostic (1.37e-1)" "unprognostic (1.28e-1)" "unprognostic (1.10e-1)" "unprognostic (3.28e-1)" "unprognostic (7.45e-2)" "unprognostic (9.88e-2)" "unprognostic (2.34e-1)" INHA ENSG00000123999 "Inhibin subunit alpha" P05111 2 219569162-219575711 "Predicted secreted proteins" "Growth factor, Hormone" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "adrenal gland: 75.8;ovary: 108.7;testis: 101.4" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 48.3;Cardiomyocytes: 105.5;Extravillous trophoblasts: 60.8;Granulosa cells: 248.2;Migrating cytotrophoblasts: 39.3;Ovarian stromal cells: 67.9;Sertoli cells: 61.6;Syncytiotrophoblasts: 444.4" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 12.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB000047, HPA019141, HPA048834" Enhanced Approved "Golgi apparatus,Vesicles" "Secreted to blood" Hormone NA NA 26000 "Cluster 75: Ovary - Mixed function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." 1 Vesicles "Golgi apparatus" "CAB000047: , HPA019141: , HPA048834: " "unprognostic (8.30e-3)" "unprognostic (1.17e-3)" "unprognostic (2.88e-1)" "unprognostic (1.52e-1)" "unprognostic (1.19e-3)" "unprognostic (1.33e-2)" "potential prognostic unfavorable (1.50e-4)" "unprognostic (1.15e-1)" "unprognostic (1.13e-2)" "unprognostic (2.89e-1)" "unprognostic (4.94e-2)" "unprognostic (2.62e-3)" "unprognostic (9.15e-2)" "unprognostic (3.21e-1)" "unprognostic (7.90e-2)" "unprognostic (1.37e-1)" "unprognostic (2.81e-1)" "unprognostic (1.68e-1)" "unprognostic (6.94e-2)" "unprognostic (1.44e-1)" "unprognostic (1.41e-1)" INHBA ENSG00000122641 "Inhibin subunit beta A" P08476 7 41667168-41705834 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Growth factor, Hormone" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 18.6;gallbladder: 20.2" "Cell type enhanced" "Detected in many" "Fibroblasts: 345.8;Hepatic stellate cells: 64.5;Leydig cells: 225.4;Macrophages: 63.0;Neutrophil progenitors: 165.7;Pancreatic islet cells: 127.0;Syncytiotrophoblasts: 253.2;Vascular smooth muscle cells: 109.2" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 49.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "thyroid cancer: 141.6" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted to blood" Hormone NA NA 350000 "Cluster 13: Lung - Secretion" "Cluster 29: Forebrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 17: Non-specific - RNA processing" 6 "unprognostic (2.39e-1)" "unprognostic (1.43e-2)" "unprognostic (1.14e-1)" "potential prognostic unfavorable (5.35e-5)" "unprognostic (3.14e-2)" "unprognostic (4.07e-2)" "unprognostic (9.57e-2)" "unprognostic (4.67e-2)" "potential prognostic unfavorable (4.11e-4)" "unprognostic (1.12e-1)" "unprognostic (3.39e-2)" "unprognostic (4.90e-2)" "potential prognostic unfavorable (4.41e-5)" "unprognostic (1.25e-2)" "unprognostic (1.27e-1)" "unprognostic (9.22e-3)" "unprognostic (1.19e-2)" "unprognostic (6.59e-3)" "unprognostic (5.57e-2)" "unprognostic (9.25e-2)" "potential prognostic unfavorable (1.85e-7)" "unprognostic (7.79e-3)" "unprognostic (2.51e-1)" "unprognostic (1.53e-1)" "unprognostic (3.01e-1)" "unprognostic (4.10e-3)" "unprognostic (9.22e-2)" "unprognostic (2.29e-3)" "unprognostic (7.24e-2)" "unprognostic (3.73e-2)" "unprognostic (2.29e-1)" INHBB ENSG00000163083 "Inhibin subunit beta B" P09529 2 120346136-120351803 "Cancer-related genes, Predicted secreted proteins" "Growth factor, Hormone" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 49.6;breast: 42.2" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 81.8;Breast myoepithelial cells: 30.1;Breast secretory cells: 30.2;Hepatocytes: 28.4;Myosatellite cells: 29.8;Neutrophils: 33.4;Pituitary stem cells: 40.4;Prostatic glandular cells: 48.9;Respiratory ciliated cells: 73.8;Salivary acinar cells: 30.0;Salivary duct cells: 37.1;Sertoli cells: 32.1;Submucosal glandular cells: 42.3;Transitional alveolar cells: 31.1;Vascular endothelial cells: 52.4" "Cell type enhanced" "Detected in many" "astrocyte: 15.0;ependymal cell: 21.6;fibroblast: 16.2" "Cancer enhanced" "Detected in all" "Thyroid Carcinoma (TCGA): 63.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 49.5" "Colon - Endothelial cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA079405 Approved Vesicles "Secreted to blood" Hormone NA NA 98000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 19: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 2 Vesicles "HPA079405: " "unprognostic (1.16e-2)" "unprognostic (1.88e-3)" "unprognostic (7.14e-2)" "unprognostic (4.30e-1)" "unprognostic (3.32e-3)" "unprognostic (3.43e-2)" "unprognostic (3.07e-2)" "potential prognostic unfavorable (8.06e-4)" "unprognostic (2.06e-3)" "unprognostic (2.13e-1)" "unprognostic (9.03e-2)" "unprognostic (1.48e-2)" "unprognostic (7.01e-3)" "unprognostic (2.11e-2)" "unprognostic (8.58e-3)" "unprognostic (2.25e-1)" "unprognostic (6.25e-2)" "unprognostic (5.16e-2)" "unprognostic (2.00e-2)" "unprognostic (2.75e-1)" "unprognostic (2.26e-1)" "unprognostic (1.13e-1)" "unprognostic (2.80e-2)" "unprognostic (3.01e-2)" "unprognostic (3.03e-3)" "unprognostic (2.25e-2)" "unprognostic (3.19e-1)" "potential prognostic unfavorable (1.95e-4)" "unprognostic (1.13e-1)" "unprognostic (3.30e-3)" "unprognostic (6.65e-3)" INHBC ENSG00000175189 "Inhibin subunit beta C" P55103 12 57434784-57452062 "Plasma proteins, Predicted secreted proteins" "Growth factor, Hormone" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 138 "liver: 154.2" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 44.9" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 69 "Liver Hepatocellular Carcinoma (TCGA): 41.2" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 4.9" "Pituitary gland - Lactotropes, Prostate - Prostate glandular cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA050755 Approved Cytosol "Secreted to blood" Hormone NA NA 32000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 37: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 93: Hepatocytes - Bile production & excretion" Cytosol "HPA050755: " "potential prognostic favorable (5.67e-4)" "unprognostic (6.51e-3)" INHBE "activin, MGC4638" ENSG00000139269 "Inhibin subunit beta E" P58166 12 57452323-57459280 "Essential proteins, Plasma proteins, Predicted secreted proteins" "Growth factor, Hormone" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 90 "liver: 134.1" "Cell type enriched" "Detected in some" 15 "Hepatocytes: 43.0" "Cell type enhanced" "Detected in single" "Bergmann glia: 2.0" "Cancer enriched" "Detected in some" 19 "Liver Hepatocellular Carcinoma (TCGA): 53.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "Myeloma: 76.4" "Pituitary gland - Lactotropes, Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA016843, CAB034017" Enhanced Supported Vesicles "Secreted to blood" Hormone NA NA 3900000 "Cluster 53: Liver - Plasma proteins" "Cluster 35: Non-specific - DNA binding" "Cluster 13: Non-specific - Mixed function" "Cluster 93: Hepatocytes - Bile production & excretion" 9 Vesicles "CAB034017: , HPA016843: " "unprognostic (4.65e-1)" "potential prognostic unfavorable (6.08e-4)" "validated prognostic unfavorable (8.27e-9)" "validated prognostic unfavorable (4.72e-4)" "unprognostic (3.69e-2)" "unprognostic (1.90e-1)" "unprognostic (4.93e-3)" "unprognostic (1.54e-1)" "unprognostic (2.49e-2)" INIP "C9orf80, HSPC043, hSSBIP1, MISE, SOSS-C" ENSG00000148153 "INTS3 and NABP interacting protein" Q9NRY2 9 112683926-112718149 "Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020382 Approved Supported Nucleoplasm NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 28 Nucleoplasm "HPA020382: " "unprognostic (4.13e-1)" "unprognostic (3.14e-2)" "unprognostic (2.10e-1)" "unprognostic (2.82e-1)" "unprognostic (1.26e-2)" "unprognostic (8.08e-2)" "unprognostic (5.70e-2)" "unprognostic (3.28e-1)" "unprognostic (5.39e-2)" "potential prognostic favorable (2.59e-8)" "unprognostic (1.81e-3)" "unprognostic (1.67e-1)" "unprognostic (2.66e-2)" "unprognostic (2.28e-1)" "unprognostic (2.84e-1)" "unprognostic (9.93e-2)" "unprognostic (2.66e-1)" "unprognostic (1.74e-1)" "unprognostic (7.76e-2)" "unprognostic (1.94e-1)" "unprognostic (3.96e-2)" "unprognostic (3.40e-2)" "unprognostic (3.85e-2)" "unprognostic (9.69e-2)" "unprognostic (6.52e-2)" "unprognostic (1.83e-3)" "unprognostic (2.51e-1)" "unprognostic (2.72e-1)" "unprognostic (3.27e-1)" INKA1 "C3orf54, FAM212A" ENSG00000185614 "Inka box actin regulator 1" 3 49803261-49805030 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "skin 1: 23.2" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 55.6;Esophageal suprabasal cells: 58.6;Hofbauer cells: 124.8;Mast cells: 37.6;Megakaryocyte progenitors: 54.1;Megakaryocytes: 148.4;Platelets: 258.8" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 25.1;pericyte: 9.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 59.8;memory B-cell: 66.1;naive B-cell: 64.7" "Group enriched" "Detected in many" 7 "B-cells: 66.1;granulocytes: 59.8" "Group enriched" "Detected in many" 4 "Gallbladder cancer: 30.9;Leukemia: 34.5" "Skin - Keratinocyte (other), Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA041879 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 32: Basophils - Transcription" "Cluster 58: Skin - Keratinization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 35: RS4;11 - Unknown function" "Cluster 47: Platelets - Hemostasis" 1 "Nucleoplasm, Vesicles" "HPA041879: " "unprognostic (2.83e-2)" "unprognostic (3.28e-1)" "unprognostic (2.33e-3)" "unprognostic (4.54e-2)" "unprognostic (3.01e-2)" "unprognostic (7.64e-2)" "unprognostic (1.89e-1)" "potential prognostic favorable (2.80e-4)" "unprognostic (4.31e-2)" "unprognostic (4.18e-2)" "unprognostic (8.05e-3)" "unprognostic (1.67e-1)" "unprognostic (9.09e-3)" "unprognostic (2.60e-1)" "unprognostic (2.63e-1)" "unprognostic (7.41e-2)" "unprognostic (1.82e-1)" "unprognostic (4.05e-1)" "unprognostic (4.86e-2)" "unprognostic (1.48e-3)" "unprognostic (1.81e-1)" "unprognostic (1.09e-1)" "unprognostic (1.58e-2)" "unprognostic (9.74e-3)" "unprognostic (1.75e-1)" "unprognostic (3.82e-2)" "unprognostic (1.87e-1)" "unprognostic (1.48e-1)" "unprognostic (2.47e-2)" INKA2 "C1orf183, FAM212B, FLJ31105" ENSG00000197852 "Inka box actin regulator 2" Q9NTI7 1 111680630-111755824 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 84.2;Cardiomyocytes: 228.3;Epicardial cells: 120.5;Neutrophils: 163.3;Platelets: 319.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 18.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 13 "neutrophil: 25.5" "Lineage enriched" "Detected in many" 13 "granulocytes: 25.5" "Low cancer specificity" "Detected in all" "Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027809, HPA027810, HPA027811" Approved Supported Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 51: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 1 Nucleoplasm "Nucleoli, Vesicles" "HPA027809: , HPA027810: , HPA027811: " "unprognostic (1.93e-2)" "unprognostic (2.91e-2)" "unprognostic (1.39e-1)" "unprognostic (3.79e-2)" "unprognostic (1.72e-1)" "unprognostic (1.03e-2)" "unprognostic (2.16e-2)" "unprognostic (1.54e-3)" "unprognostic (1.10e-1)" "potential prognostic favorable (4.67e-4)" "unprognostic (2.41e-3)" "unprognostic (2.68e-1)" "unprognostic (8.44e-3)" "unprognostic (7.32e-2)" "unprognostic (4.07e-1)" "unprognostic (1.05e-1)" "unprognostic (1.00e-2)" "unprognostic (3.54e-2)" "unprognostic (1.08e-1)" "unprognostic (1.09e-3)" "unprognostic (1.89e-2)" "unprognostic (2.22e-1)" "unprognostic (2.60e-2)" "unprognostic (1.38e-1)" "unprognostic (1.37e-2)" "unprognostic (1.75e-1)" "unprognostic (1.45e-1)" "unprognostic (1.18e-2)" "unprognostic (4.12e-1)" INMT ENSG00000241644 "Indolethylamine N-methyltransferase" O95050 7 30697985-30757602 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Detoxification "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 195.0" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 6.9;Early spermatids: 4.8;Epicardial cells: 4.5;Late spermatids: 4.1;Mesothelial cells: 3.6;Pericytes: 3.1;Retinal amacrine cells: 2.8;Retinal horizontal cells: 8.0;Tuft cells: 11.5;Vascular endothelial cells: 8.1" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 20.7;endothelial cell: 7.3" "Cancer enhanced" "Detected in all" "Thyroid Carcinoma (TCGA): 41.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.4" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in single" "Adipose visceral - Mesothelial cells, Adrenal gland - Fibroblasts, Minor Salivary Gland - Fibroblasts, Pituitary gland - Fibroblasts, Prostate - Smooth muscle cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 6 "spinal cord: 35.6" HPA061343 Approved "Golgi apparatus,Vesicles" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 31: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 2 "Golgi apparatus, Vesicles" "HPA061343: " "unprognostic (1.17e-2)" "unprognostic (1.09e-1)" "unprognostic (5.20e-3)" "unprognostic (3.73e-2)" "unprognostic (3.30e-2)" "unprognostic (8.98e-2)" "unprognostic (6.87e-2)" "unprognostic (5.10e-3)" "potential prognostic favorable (9.19e-4)" "unprognostic (1.96e-1)" "potential prognostic favorable (4.44e-5)" "unprognostic (9.65e-3)" "potential prognostic unfavorable (2.72e-4)" "unprognostic (1.23e-3)" "potential prognostic favorable (1.44e-5)" "potential prognostic favorable (7.46e-4)" "unprognostic (1.99e-3)" "unprognostic (2.03e-2)" "unprognostic (2.74e-1)" "unprognostic (1.47e-1)" "unprognostic (1.13e-1)" "unprognostic (8.71e-2)" "unprognostic (7.96e-3)" "unprognostic (6.84e-2)" "unprognostic (6.61e-2)" "unprognostic (2.20e-2)" "unprognostic (2.39e-1)" "unprognostic (3.24e-3)" "unprognostic (2.63e-2)" "unprognostic (2.85e-1)" "unprognostic (6.21e-2)" INO80 "hINO80, INO80A, INOC1, KIAA1259" ENSG00000128908 "INO80 complex ATPase subunit" Q9ULG1 15 40978880-41116280 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA recombination, DNA repair, Host-virus interaction, Mitosis" "Actin-binding, DNA-binding, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 13 "Epicardial cells: 3547.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041417, HPA041484" Enhanced "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 55: Breast - Lactation" "Cluster 25: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 48 "Nucleoplasm, Nuclear bodies" Cytosol "HPA041417: , HPA041484: " "unprognostic (4.41e-2)" "unprognostic (3.91e-2)" "unprognostic (3.01e-1)" "unprognostic (7.82e-2)" "unprognostic (2.06e-1)" "unprognostic (1.20e-1)" "unprognostic (2.04e-1)" "unprognostic (2.83e-3)" "unprognostic (1.24e-1)" "unprognostic (1.24e-1)" "validated prognostic favorable (2.02e-6)" "validated prognostic favorable (8.32e-4)" "unprognostic (1.30e-1)" "unprognostic (5.57e-3)" "unprognostic (8.47e-2)" "unprognostic (8.60e-2)" "unprognostic (1.40e-2)" "unprognostic (9.50e-2)" "unprognostic (2.38e-3)" "unprognostic (2.75e-3)" "unprognostic (3.19e-1)" "unprognostic (1.60e-1)" "unprognostic (3.27e-2)" "unprognostic (3.34e-1)" "unprognostic (4.19e-2)" "unprognostic (1.09e-1)" "unprognostic (1.95e-2)" "unprognostic (3.61e-1)" "unprognostic (2.91e-1)" "unprognostic (7.12e-2)" "unprognostic (5.51e-2)" INO80B "hIes2, HMGA1L4, HMGIYL4, IES2, PAP-1BP, PAPA-1, ZNHIT4" ENSG00000115274 "INO80 complex subunit B" Q9C086 2 74455087-74457944 "Essential proteins, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 4.2;Bergmann glia: 5.2;Brain excitatory neurons: 5.3;Brain inhibitory neurons: 4.6;Ependymal cells: 6.5;Megakaryocytes: 6.2;Microglia: 4.2;Oligodendrocyte progenitor cells: 3.6;Oligodendrocytes: 5.1;Other brain neurons: 7.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA070644, HPA078274" Supported "Nucleoplasm,Nucleoli,Nuclear bodies" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 98: Neurons - Neurotransmission & signaling" 83 Nucleoplasm "Nucleoli, Nuclear bodies" "HPA070644: , HPA078274: " "unprognostic (3.83e-1)" "unprognostic (3.41e-3)" "unprognostic (4.95e-2)" "unprognostic (8.61e-3)" "unprognostic (2.08e-1)" "unprognostic (2.44e-1)" "unprognostic (1.95e-1)" "potential prognostic favorable (5.19e-4)" "unprognostic (1.03e-2)" "unprognostic (2.37e-1)" "unprognostic (7.62e-3)" "unprognostic (3.25e-1)" "unprognostic (2.97e-1)" "unprognostic (5.43e-3)" "unprognostic (9.00e-2)" "unprognostic (2.90e-2)" "unprognostic (8.00e-2)" "unprognostic (8.26e-3)" "unprognostic (9.40e-2)" "unprognostic (1.58e-1)" "unprognostic (5.29e-2)" "unprognostic (2.22e-1)" "unprognostic (6.14e-2)" "unprognostic (4.96e-2)" "unprognostic (2.82e-1)" "unprognostic (1.56e-1)" "unprognostic (3.92e-2)" "unprognostic (1.97e-2)" "unprognostic (1.83e-1)" "unprognostic (2.67e-1)" "unprognostic (5.32e-2)" INO80C "C18orf37, FLJ38183, hIes6, IES6" ENSG00000153391 "INO80 complex subunit C" Q6PI98 18 35452230-35497979 "Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 32.4;Esophageal apical cells: 20.1;Gastric chief cells: 28.4;Late primary spermatocytes: 88.9;Suprabasal keratinocytes: 14.2" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041731, HPA049060" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol" NA NA "Cluster 32: Basophils - Transcription" "Cluster 39: Testis - Nuclear processes" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 13: Non-specific - Mixed function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 42 Nucleoplasm "Nucleoli fibrillar center, Vesicles, Cytosol" "HPA041731: , HPA049060: " "unprognostic (6.80e-2)" "unprognostic (1.20e-1)" "unprognostic (2.87e-2)" "unprognostic (3.29e-2)" "unprognostic (3.04e-1)" "unprognostic (1.21e-1)" "unprognostic (1.25e-1)" "potential prognostic favorable (8.84e-5)" "unprognostic (8.81e-2)" "unprognostic (3.88e-2)" "validated prognostic favorable (1.43e-5)" "validated prognostic favorable (2.44e-4)" "unprognostic (1.05e-2)" "unprognostic (4.00e-3)" "unprognostic (1.93e-3)" "unprognostic (2.96e-2)" "unprognostic (1.09e-1)" "unprognostic (1.97e-1)" "unprognostic (2.81e-2)" "unprognostic (2.79e-3)" "unprognostic (1.18e-1)" "unprognostic (5.23e-3)" "unprognostic (1.83e-2)" "unprognostic (8.89e-3)" "unprognostic (3.53e-1)" "unprognostic (2.15e-1)" "unprognostic (6.26e-2)" "unprognostic (1.08e-1)" "unprognostic (2.67e-3)" "unprognostic (6.22e-3)" "unprognostic (2.32e-1)" INO80D FLJ20309 ENSG00000114933 "INO80 complex subunit D" Q53TQ3 2 205993721-206086303 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.0" "Cell type enhanced" "Detected in many" "Astrocytes: 65.6;Bergmann glia: 82.7;Brain excitatory neurons: 67.7;Brain inhibitory neurons: 65.5;Choroid plexus epithelial cells: 116.9;Distal convoluted tubule cells: 126.9;Ependymal cells: 55.7;Loop of henle epithelial cells: 103.5;Microglia: 79.3;Oligodendrocyte progenitor cells: 71.0;Oligodendrocytes: 83.2;Papillary tip epithelial cells: 73.9;Podocytes: 101.7;Proximal tubule cells: 139.7;Renal collecting duct intercalated cells: 138.6;Renal collecting duct principal cells: 79.1;Renal connecting tubule cells: 115.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043976 Approved NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 15: Bone marrow - Innate immune response" "Cluster 16: Non-specific - Transcription" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 102: Non-specific - Mixed function" 12 "HPA043976: " "unprognostic (9.16e-2)" "unprognostic (2.75e-1)" "unprognostic (2.96e-2)" "unprognostic (9.80e-3)" "unprognostic (4.75e-3)" "unprognostic (1.85e-2)" "unprognostic (1.54e-1)" "unprognostic (4.40e-2)" "unprognostic (2.85e-2)" "unprognostic (2.43e-1)" "unprognostic (1.58e-1)" "unprognostic (4.22e-2)" "unprognostic (1.23e-1)" "unprognostic (1.51e-2)" "unprognostic (1.14e-1)" "unprognostic (1.95e-2)" "unprognostic (1.55e-1)" "unprognostic (6.90e-3)" "unprognostic (3.19e-1)" "unprognostic (2.67e-2)" "unprognostic (1.12e-2)" "unprognostic (8.79e-2)" "unprognostic (5.20e-3)" "unprognostic (1.54e-1)" "unprognostic (1.42e-1)" "unprognostic (4.60e-2)" "unprognostic (8.24e-2)" "unprognostic (2.47e-1)" "unprognostic (2.07e-1)" "unprognostic (2.96e-2)" "unprognostic (1.91e-1)" INO80E "CCDC95, FLJ90652" ENSG00000169592 "INO80 complex subunit E" Q8NBZ0 16 29995715-30005793 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043146 Approved Supported "Nucleoplasm,Nucleoli rim" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 64: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 63 Nucleoplasm "Nucleoli rim" "HPA043146: " "unprognostic (1.54e-1)" "unprognostic (8.05e-2)" "unprognostic (8.79e-2)" "unprognostic (7.40e-2)" "unprognostic (1.90e-1)" "unprognostic (1.53e-1)" "unprognostic (1.22e-1)" "unprognostic (9.34e-3)" "unprognostic (3.27e-1)" "unprognostic (1.99e-1)" "unprognostic (2.53e-2)" "unprognostic (2.46e-1)" "unprognostic (2.93e-1)" "unprognostic (4.09e-3)" "unprognostic (1.04e-1)" "unprognostic (4.98e-2)" "unprognostic (3.06e-2)" "unprognostic (2.64e-1)" "unprognostic (1.81e-1)" "unprognostic (2.50e-2)" "unprognostic (2.42e-2)" "unprognostic (1.60e-2)" "unprognostic (9.03e-3)" "unprognostic (1.30e-1)" "unprognostic (1.91e-1)" "unprognostic (3.60e-1)" "unprognostic (4.60e-1)" "unprognostic (1.35e-1)" "unprognostic (3.83e-1)" "unprognostic (5.23e-2)" "unprognostic (3.80e-2)" INPP1 ENSG00000151689 "Inositol polyphosphate-1-phosphatase" P49441 2 190343570-190371665 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 898.1;Esophageal suprabasal cells: 352.2;Late spermatids: 1284.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 96.3" "Lineage enriched" "Detected in all" 5 "granulocytes: 96.3" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Lung - Endothelial cells, Spleen - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036698, HPA036699" Supported Approved "Centriolar satellite,Cytosol" NA NA 49000 "Cluster 19: Eosinophils - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 11: White matter - Signal transduction" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 5 "Centriolar satellite" Cytosol "HPA036698: , HPA036699: " "unprognostic (4.39e-2)" "unprognostic (1.05e-2)" "unprognostic (2.51e-1)" "unprognostic (3.27e-2)" "unprognostic (6.87e-2)" "unprognostic (6.13e-3)" "unprognostic (8.35e-2)" "unprognostic (2.98e-2)" "unprognostic (9.12e-3)" "unprognostic (3.94e-2)" "potential prognostic favorable (1.84e-7)" "unprognostic (1.68e-3)" "unprognostic (4.20e-2)" "unprognostic (4.16e-2)" "unprognostic (1.85e-2)" "unprognostic (4.56e-1)" "unprognostic (2.12e-2)" "unprognostic (7.93e-2)" "unprognostic (2.50e-2)" "unprognostic (2.28e-1)" "unprognostic (1.41e-1)" "unprognostic (5.73e-2)" "unprognostic (2.03e-1)" "unprognostic (1.13e-1)" "unprognostic (3.53e-1)" "unprognostic (1.32e-1)" "unprognostic (1.89e-3)" "unprognostic (9.41e-2)" "unprognostic (1.81e-1)" "unprognostic (9.68e-3)" "unprognostic (6.77e-3)" INPP4A INPP4 ENSG00000040933 "Inositol polyphosphate-4-phosphatase type I A" Q96PE3 2 98444854-98594392 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 340.1;NK-cells: 267.1;pDCs: 571.8;Renal collecting duct intercalated cells: 332.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Myeloma: 79.4" "Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001628 Approved Supported "Nucleoplasm,Nuclear membrane" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 24: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" "Nucleoplasm, Nuclear membrane" "HPA001628: " "unprognostic (8.27e-3)" "unprognostic (1.80e-2)" "unprognostic (9.38e-3)" "unprognostic (4.15e-1)" "unprognostic (2.48e-1)" "unprognostic (1.92e-1)" "unprognostic (3.45e-1)" "unprognostic (2.23e-1)" "unprognostic (9.28e-2)" "unprognostic (5.77e-2)" "unprognostic (5.13e-3)" "unprognostic (4.22e-2)" "unprognostic (3.48e-2)" "unprognostic (2.13e-3)" "unprognostic (2.90e-1)" "unprognostic (1.22e-1)" "unprognostic (2.14e-1)" "unprognostic (2.81e-1)" "unprognostic (2.70e-2)" "unprognostic (2.59e-2)" "unprognostic (1.24e-2)" "unprognostic (2.14e-1)" "unprognostic (3.37e-2)" "unprognostic (8.97e-2)" "unprognostic (2.79e-1)" "unprognostic (7.62e-3)" "unprognostic (6.20e-2)" "unprognostic (2.16e-1)" "unprognostic (3.69e-1)" "unprognostic (1.12e-2)" "unprognostic (1.86e-2)" INPP4B ENSG00000109452 "Inositol polyphosphate-4-phosphatase type II B" O15327 4 142023160-142847432 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 881.1;Decidual stromal cells: 811.9;Endometrial stromal cells: 1103.0;Hematopoietic stem cells: 2670.7;Megakaryocyte progenitors: 1008.6;Melanocytes: 1699.8;Other brain neurons: 859.0;Pericytes: 1081.0;Urothelial cells: 816.5" "Cell type enhanced" "Detected in all" "cerebellar inhibitory: 4297.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory CD4 T-cell: 30.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Liver - Hepatic stellate cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037681, HPA037682" Approved Approved Centrosome NA NA "Cluster 11: T-cells - Unknown function" "Cluster 57: Testis - Spermatogenesis" "Cluster 38: Sub-cortical - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 110: Mural cells - ECM organization" 1 Centrosome "HPA037681: , HPA037682: " "unprognostic (3.32e-2)" "unprognostic (1.23e-1)" "unprognostic (1.71e-2)" "unprognostic (1.42e-2)" "unprognostic (7.98e-2)" "unprognostic (8.50e-2)" "unprognostic (2.58e-1)" "unprognostic (1.94e-1)" "unprognostic (2.74e-2)" "unprognostic (4.29e-2)" "validated prognostic favorable (1.09e-6)" "validated prognostic favorable (3.37e-4)" "unprognostic (1.13e-1)" "unprognostic (1.75e-1)" "unprognostic (1.24e-2)" "unprognostic (6.51e-3)" "unprognostic (5.05e-3)" "potential prognostic unfavorable (1.40e-5)" "unprognostic (3.48e-1)" "unprognostic (1.17e-2)" "potential prognostic unfavorable (4.59e-5)" "unprognostic (3.91e-2)" "unprognostic (8.58e-2)" "unprognostic (3.34e-2)" "unprognostic (1.81e-1)" "unprognostic (9.38e-2)" "unprognostic (2.50e-2)" "unprognostic (1.16e-1)" "unprognostic (3.75e-2)" "unprognostic (5.30e-2)" INPP5A 5PTASE ENSG00000068383 "Inositol polyphosphate-5-phosphatase A" Q14642 10 132537787-132783480 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Neutrophils: 814.4" "Cell type enhanced" "Detected in all" "medium spiny neuron: 311.8;vascular associated smooth muscle cell: 268.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "basophil: 6.7" "Lineage enriched" "Detected in single" 29 "granulocytes: 6.7" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Prostate - Smooth muscle cells" "Region enhanced" "Detected in all" "cerebellum: 250.8" "Low region specificity" "Detected in all" HPA012285 Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 15: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 2 Cytosol "Plasma membrane" "HPA012285: " "unprognostic (1.38e-1)" "potential prognostic unfavorable (3.33e-5)" "unprognostic (5.87e-2)" "potential prognostic unfavorable (7.84e-4)" "unprognostic (8.24e-3)" "unprognostic (3.95e-2)" "unprognostic (7.41e-2)" "unprognostic (7.14e-3)" "unprognostic (1.88e-2)" "unprognostic (5.02e-2)" "validated prognostic favorable (3.75e-8)" "validated prognostic favorable (2.59e-5)" "unprognostic (8.83e-2)" "unprognostic (1.29e-1)" "unprognostic (2.22e-3)" "unprognostic (3.67e-3)" "unprognostic (2.09e-1)" "unprognostic (6.17e-2)" "unprognostic (9.46e-2)" "unprognostic (6.36e-2)" "unprognostic (1.01e-3)" "unprognostic (1.41e-1)" "unprognostic (1.10e-1)" "unprognostic (1.36e-2)" "unprognostic (3.14e-1)" "unprognostic (3.71e-2)" "unprognostic (1.32e-1)" "unprognostic (3.44e-1)" "unprognostic (6.03e-2)" "unprognostic (4.13e-2)" "unprognostic (1.76e-1)" INPP5B ENSG00000204084 "Inositol polyphosphate-5-phosphatase B" P32019 1 37860697-37947057 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 145.7;Retinal ganglion cells: 166.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028803 Approved Supported "Primary cilium tip,Cytosol" NA NA "Cluster 32: Basophils - Transcription" "Cluster 49: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 37: Non-specific - mRNA processing" "Cluster 7: Non-specific - Transcription" 2 Cytosol "Primary cilium tip" "HPA028803: " "unprognostic (2.92e-2)" "unprognostic (8.74e-2)" "unprognostic (1.02e-1)" "unprognostic (1.56e-1)" "unprognostic (1.25e-1)" "unprognostic (8.00e-2)" "unprognostic (7.45e-3)" "unprognostic (7.71e-2)" "potential prognostic favorable (3.03e-4)" "unprognostic (2.85e-2)" "unprognostic (1.76e-1)" "unprognostic (2.91e-2)" "unprognostic (4.62e-1)" "unprognostic (6.60e-3)" "unprognostic (1.27e-2)" "potential prognostic favorable (8.55e-5)" "unprognostic (1.58e-1)" "unprognostic (5.29e-2)" "unprognostic (3.27e-2)" "unprognostic (4.88e-2)" "unprognostic (2.01e-1)" "potential prognostic favorable (4.53e-4)" "unprognostic (3.92e-2)" "unprognostic (4.12e-1)" "unprognostic (1.83e-1)" "unprognostic (1.51e-2)" "unprognostic (6.23e-2)" "unprognostic (1.91e-2)" "unprognostic (1.49e-1)" "unprognostic (1.13e-1)" "unprognostic (1.39e-1)" INPP5D "hp51CN, SHIP, SHIP1" ENSG00000168918 "Inositol polyphosphate-5-phosphatase D" Q92835 2 233059967-233207903 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Immunity, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 47.7;lymphoid tissue: 95.6" "Cell type enriched" "Detected in many" 10 "Microglia: 1021.1" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 1257.2;endothelial cell: 300.2;leukocyte: 431.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 43.8;lymphoma: 38.7" "Adipose subcutaneous - T-cells, Breast - T-cells, Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Endothelial cells, Spleen - B-cells (Spleen), Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016300, HPA070455" Enhanced Supported Cytosol No No 830000 "Cluster 40: Monocytes - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 102: Non-specific - Mixed function" 24 Cytosol "CAB016300: , HPA070455: " "unprognostic (6.03e-3)" "unprognostic (1.13e-1)" "unprognostic (1.51e-2)" "unprognostic (1.78e-1)" "unprognostic (2.59e-1)" "unprognostic (1.29e-1)" "unprognostic (2.62e-1)" "unprognostic (9.69e-2)" "potential prognostic favorable (7.21e-5)" "unprognostic (4.70e-2)" "unprognostic (7.17e-2)" "unprognostic (3.52e-2)" "unprognostic (2.70e-2)" "unprognostic (1.25e-1)" "unprognostic (1.84e-2)" "unprognostic (5.20e-2)" "unprognostic (3.41e-2)" "unprognostic (6.36e-2)" "unprognostic (3.24e-1)" "unprognostic (1.72e-1)" "unprognostic (2.77e-1)" "unprognostic (2.18e-1)" "unprognostic (8.93e-3)" "unprognostic (8.03e-2)" "unprognostic (1.01e-1)" "unprognostic (6.53e-2)" "unprognostic (2.21e-1)" "unprognostic (1.99e-1)" "unprognostic (4.65e-2)" "unprognostic (1.55e-2)" "unprognostic (1.40e-1)" INPP5E "CORS1, JBTS1, pharbin, PPI5PIV" ENSG00000148384 "Inositol polyphosphate-5-phosphatase E" Q9NRR6 9 136428619-136439845 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" Hydrolase "Ciliopathy, Disease variant, Intellectual disability, Joubert syndrome, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fallopian tube ciliated cells: 26.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065758 Approved Uncertain "Nucleoplasm,Golgi apparatus,Focal adhesion sites" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 107: Ciliated cells - Cilia assembly & function" 19 "Golgi apparatus" "Nucleoplasm, Focal adhesion sites" "HPA065758: " "unprognostic (3.98e-2)" "unprognostic (5.99e-2)" "unprognostic (1.15e-1)" "potential prognostic unfavorable (8.48e-4)" "unprognostic (3.03e-2)" "unprognostic (3.05e-3)" "unprognostic (2.28e-1)" "unprognostic (5.24e-3)" "unprognostic (4.42e-2)" "unprognostic (1.68e-2)" "unprognostic (7.40e-3)" "unprognostic (3.40e-1)" "unprognostic (5.41e-2)" "unprognostic (3.41e-2)" "unprognostic (1.27e-1)" "unprognostic (5.42e-2)" "unprognostic (3.55e-1)" "unprognostic (2.42e-3)" "unprognostic (3.57e-3)" "unprognostic (1.22e-1)" "unprognostic (2.76e-3)" "unprognostic (9.43e-3)" "unprognostic (3.11e-2)" "unprognostic (4.36e-2)" "unprognostic (5.04e-2)" "unprognostic (8.12e-3)" "unprognostic (1.64e-1)" "unprognostic (3.52e-1)" "unprognostic (1.02e-2)" "unprognostic (2.00e-1)" "unprognostic (1.18e-1)" INPP5F "hSac2, KIAA0966, SAC2" ENSG00000198825 "Inositol polyphosphate-5-phosphatase F" Q9Y2H2 10 119726042-119829147 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 137.7" "Cell type enhanced" "Detected in all" "Bergmann glia: 516.9;Other brain neurons: 170.0" "Cell type enhanced" "Detected in all" "Bergmann glia: 569.3" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 71.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in all" 5 "skin cancer: 74.7;testis cancer: 167.2" "Prostate - Fibroblasts, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042605 Supported Vesicles NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 1: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 82: Dendritic cells - Antigen presentation" 11 Vesicles "HPA042605: " "unprognostic (4.43e-2)" "unprognostic (6.84e-3)" "unprognostic (9.93e-2)" "unprognostic (1.22e-1)" "unprognostic (5.82e-2)" "unprognostic (1.52e-1)" "unprognostic (2.52e-2)" "potential prognostic favorable (1.63e-5)" "unprognostic (8.80e-2)" "unprognostic (2.75e-1)" "unprognostic (1.42e-3)" "potential prognostic favorable (1.06e-4)" "unprognostic (2.07e-2)" "potential prognostic unfavorable (3.99e-5)" "unprognostic (2.52e-1)" "unprognostic (4.81e-1)" "unprognostic (1.98e-2)" "unprognostic (2.08e-2)" "unprognostic (3.03e-2)" "unprognostic (3.33e-2)" "potential prognostic unfavorable (9.12e-6)" "unprognostic (7.11e-2)" "unprognostic (2.10e-2)" "unprognostic (7.41e-2)" "unprognostic (2.99e-2)" "unprognostic (6.48e-2)" "unprognostic (1.34e-1)" "unprognostic (1.19e-1)" "unprognostic (1.25e-1)" "unprognostic (6.32e-2)" "unprognostic (3.40e-2)" INPP5J "INPP5, PIB5PA, PIPP" ENSG00000185133 "Inositol polyphosphate-5-phosphatase J" Q15735 22 31122731-31134697 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 115.7;thyroid gland: 191.9" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 33.2;Colonocytes: 28.2;Distal convoluted tubule cells: 65.3;Enterocytes: 72.3;Epididymal clear cells: 30.6;Müller glia: 33.6;Renal collecting duct intercalated cells: 45.8;Renal collecting duct principal cells: 30.2;Renal connecting tubule cells: 58.8;Retinal ganglion cells: 42.5;Salivary duct cells: 24.8;Tuft cells: 34.6" "Cell type enhanced" "Detected in many" "mammillary body: 51.1" "Group enriched" "Detected in many" 12 "Kidney Chromophobe (TCGA): 279.3;Thyroid Carcinoma (TCGA): 159.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 12.3" "Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2, Prostate - Prostate basal glandular cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes" "Region enhanced" "Detected in all" "olfactory bulb: 131.0" "Low region specificity" "Detected in all" HPA034539 Approved "Nucleoli fibrillar center,Cytosol" NA NA "Cluster 69: Parathyroid gland - Mixed function" "Cluster 35: Non-specific - DNA binding" "Cluster 27: Breast cancer - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 15 Cytosol "Nucleoli fibrillar center" "HPA034539: " "unprognostic (4.32e-2)" "unprognostic (1.74e-1)" "unprognostic (5.55e-2)" "unprognostic (1.46e-1)" "unprognostic (1.22e-1)" "unprognostic (3.90e-2)" "unprognostic (1.55e-1)" "unprognostic (3.77e-2)" "unprognostic (1.42e-1)" "unprognostic (7.94e-2)" "unprognostic (1.71e-1)" "unprognostic (2.70e-3)" "potential prognostic favorable (2.33e-5)" "unprognostic (9.26e-2)" "unprognostic (1.17e-1)" "unprognostic (8.12e-3)" "unprognostic (1.53e-1)" "unprognostic (9.22e-2)" "potential prognostic favorable (8.84e-4)" "unprognostic (1.32e-1)" "unprognostic (5.67e-2)" "potential prognostic favorable (2.25e-4)" "unprognostic (5.24e-2)" "unprognostic (7.62e-2)" "unprognostic (2.54e-3)" "unprognostic (5.01e-2)" "unprognostic (1.67e-1)" "unprognostic (4.32e-2)" INPP5K SKIP ENSG00000132376 "Inositol polyphosphate-5-phosphatase K" Q9BT40 17 1494577-1516742 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" Hydrolase "Cataract, Congenital muscular dystrophy, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 137.9" "Group enriched" "Detected in many" 6 "Late spermatids: 612.1;Retinal pigment epithelial cells: 929.3" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 50.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Minor Salivary Gland - Minor salivary glandular cells, Skin - Keratinocyte (granular), Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 42: Non-specific - Unknown function" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" 19 "unprognostic (3.36e-3)" "unprognostic (3.60e-2)" "unprognostic (2.78e-1)" "unprognostic (2.58e-2)" "unprognostic (5.95e-2)" "unprognostic (6.25e-2)" "unprognostic (4.07e-1)" "unprognostic (3.65e-2)" "unprognostic (2.11e-1)" "unprognostic (1.01e-1)" "validated prognostic favorable (8.72e-7)" "validated prognostic favorable (2.19e-5)" "unprognostic (4.80e-2)" "unprognostic (1.24e-1)" "unprognostic (1.61e-1)" "unprognostic (9.64e-2)" "unprognostic (5.08e-2)" "unprognostic (8.08e-2)" "unprognostic (2.98e-1)" "unprognostic (1.52e-1)" "unprognostic (7.63e-2)" "potential prognostic favorable (1.12e-5)" "unprognostic (2.34e-1)" "unprognostic (4.75e-2)" "unprognostic (3.16e-1)" "unprognostic (8.42e-2)" "unprognostic (2.43e-1)" "unprognostic (1.08e-1)" "unprognostic (4.68e-1)" "unprognostic (2.04e-2)" "unprognostic (1.75e-2)" INPPL1 SHIP2 ENSG00000165458 "Inositol polyphosphate phosphatase like 1" O15357 11 72223701-72239147 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell adhesion, Immunity, Lipid metabolism" "Actin-binding, Hydrolase" "Cancer-related genes, Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cell type enhanced" "Detected in many" "astrocyte: 76.3;central nervous system macrophage: 54.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037601 Approved Supported "Golgi apparatus,Cytosol" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 24: Non-specific - Transcription" "Cluster 19: Astrocytes - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 71 Cytosol "Golgi apparatus" "HPA037601: " "unprognostic (2.13e-2)" "unprognostic (3.31e-1)" "unprognostic (3.34e-3)" "unprognostic (1.05e-2)" "unprognostic (8.53e-2)" "unprognostic (4.39e-2)" "unprognostic (7.21e-3)" "unprognostic (1.39e-1)" "unprognostic (3.62e-1)" "unprognostic (5.19e-2)" "unprognostic (1.94e-2)" "unprognostic (6.16e-2)" "unprognostic (5.77e-3)" "potential prognostic unfavorable (1.21e-4)" "unprognostic (2.55e-1)" "unprognostic (6.71e-2)" "unprognostic (2.96e-2)" "unprognostic (1.48e-2)" "unprognostic (9.30e-2)" "unprognostic (7.15e-3)" "unprognostic (5.40e-2)" "unprognostic (1.25e-1)" "potential prognostic unfavorable (9.60e-4)" "potential prognostic unfavorable (9.11e-4)" "unprognostic (2.82e-2)" "unprognostic (1.22e-2)" "unprognostic (2.58e-2)" "unprognostic (1.25e-1)" "unprognostic (2.04e-1)" "unprognostic (1.67e-3)" "unprognostic (5.92e-2)" INS "IDDM1, IDDM2" ENSG00000254647 Insulin P01308 11 2159779-2161221 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Carbohydrate metabolism, Glucose metabolism" Hormone "Cancer-related genes, Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 135 "pancreas: 12197.1" "Cell type enriched" "Detected in some" 601 "Pancreatic islet cells: 83209.9" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5079 "Pancreatic Adenocarcinoma (TCGA): 10322.5" "Region enhanced" "Detected in single" "pons: 1.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Bone cancer: 8.4;ovarian cancer: 2.2" "Adrenal gland - Adrenal medulla cells, Pancreas - Beta cells" "Low region specificity" "Detected in many" "Region enriched" "Detected in single" 13 "midbrain: 1.7" "CAB000048, HPA004932, CAB012098, CAB053843" Enhanced "Secreted to blood" Hormone NA NA 437000 4100000 "Cluster 8: Pancreas - Proteolysis" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 10 "CAB000048: , CAB012098: , CAB053843: , HPA004932: " "unprognostic (7.22e-2)" "unprognostic (8.76e-2)" INS-IGF2 ENSG00000129965 "INS-IGF2 readthrough" F8WCM5 11 2132538-2161209 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "pancreas: 8.3;placenta: 2.1" "Cell type enriched" "Detected in some" 30 "Pancreatic islet cells: 38.1" "Cancer enriched" "Detected in single" 52 "Pancreatic Adenocarcinoma (TCGA): 5.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Neuroblastoma: 1.6;Sarcoma: 1.3" "CAB019430, HPA071234" Enhanced Uncertain Nucleoplasm "Secreted to digestive system" "No annotated function" NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" Nucleoplasm "CAB019430: , HPA071234: " "unprognostic (1.15e-1)" INSC ENSG00000188487 "INSC spindle orientation adaptor protein" Q1MX18 11 15112424-15247208 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "parathyroid gland: 23.8" "Cell type enhanced" "Detected in some" "Breast lactating cells: 11.1;Foveolar cells: 18.9;Neutrophil progenitors: 9.8;Oligodendrocyte progenitor cells: 12.1;Oocytes: 13.8;Prostatic club cells: 29.9;Schwann cells: 117.2;Thyrotrophs: 13.7" "Group enriched" "Detected in some" 5 "choroid plexus epithelial cell: 19.0;oligodendrocyte precursor cell: 14.5" "Cancer enhanced" "Detected in some" "Skin Cutaneous Melanoma (TCGA): 5.4" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "thyroid cancer: 3.4" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA039769 Uncertain NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 11: Neuronal - Sensory perception" "Cluster 61: Schwann cells & Melanocytes - Mixed function" 11 "HPA039769: " "unprognostic (6.66e-3)" "unprognostic (4.60e-1)" "unprognostic (1.20e-1)" "unprognostic (2.61e-1)" "unprognostic (3.17e-3)" "unprognostic (7.79e-2)" INSIG1 "CL-6, MGC1405" ENSG00000186480 "Insulin induced gene 1" O15503 7 155297776-155310235 "Plasma proteins, Predicted membrane proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 526.8" "Cell type enhanced" "Detected in many" "cDC: 1590.9;Epididymal principal cells: 535.8;Esophageal apical cells: 413.8;Hepatocytes: 687.0;Macrophages: 407.9;monocytes: 476.3;Parietal cells: 505.6" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 4 "Liver Hepatocellular Carcinoma (TCGA): 236.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "intermediate monocyte: 273.2;non-classical monocyte: 503.5" "Lineage enriched" "Detected in all" 6 "monocytes: 503.5" "Cancer enhanced" "Detected in all" "Myeloma: 314.2" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071524 Uncertain Vesicles NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 49: Hindbrain - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 82: Dendritic cells - Antigen presentation" 13 Vesicles "HPA071524: " "unprognostic (1.18e-1)" "unprognostic (2.30e-1)" "unprognostic (5.70e-2)" "unprognostic (6.47e-2)" "unprognostic (2.49e-1)" "unprognostic (1.21e-1)" "unprognostic (8.11e-2)" "unprognostic (3.21e-2)" "unprognostic (6.63e-2)" "unprognostic (1.88e-2)" "potential prognostic favorable (1.49e-4)" "unprognostic (4.50e-2)" "unprognostic (3.03e-1)" "unprognostic (3.55e-2)" "unprognostic (2.38e-3)" "unprognostic (3.21e-1)" "unprognostic (2.44e-1)" "unprognostic (2.67e-1)" "unprognostic (2.22e-1)" "unprognostic (2.82e-1)" "unprognostic (3.03e-2)" "unprognostic (4.20e-2)" "unprognostic (1.07e-2)" "unprognostic (3.51e-1)" "unprognostic (1.57e-1)" "unprognostic (2.26e-1)" "unprognostic (3.00e-2)" "unprognostic (1.38e-1)" "unprognostic (2.60e-1)" "potential prognostic unfavorable (5.06e-4)" "unprognostic (1.92e-2)" INSIG2 ENSG00000125629 "Insulin induced gene 2" Q9Y5U4 2 118088452-118110997 "Predicted membrane proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pancreatic acinar cells: 126.1;Pancreatic duct cells: 135.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB033861 Uncertain NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 35: Non-specific - DNA binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 8: Non-specific - Secretory pathway" 42 "CAB033861: " "unprognostic (1.40e-2)" "unprognostic (3.66e-3)" "unprognostic (6.50e-2)" "potential prognostic unfavorable (4.23e-4)" "unprognostic (2.17e-1)" "unprognostic (5.16e-2)" "unprognostic (1.29e-2)" "unprognostic (1.17e-2)" "unprognostic (3.90e-2)" "unprognostic (3.73e-1)" "validated prognostic favorable (3.99e-6)" "validated prognostic favorable (6.65e-6)" "unprognostic (6.14e-2)" "unprognostic (1.26e-2)" "unprognostic (4.57e-1)" "unprognostic (1.26e-1)" "unprognostic (1.51e-1)" "unprognostic (1.47e-1)" "unprognostic (2.09e-1)" "unprognostic (7.01e-2)" "unprognostic (1.72e-1)" "validated prognostic unfavorable (1.29e-6)" "validated prognostic unfavorable (4.88e-4)" "unprognostic (1.72e-1)" "unprognostic (6.32e-3)" "unprognostic (1.57e-1)" "unprognostic (2.60e-1)" "unprognostic (1.17e-1)" "unprognostic (6.46e-2)" "unprognostic (8.30e-2)" "unprognostic (3.67e-2)" INSL3 "MGC119818, MGC119819, RLF, RLNL" ENSG00000248099 "Insulin like 3" P51460 19 17816512-17821574 "Disease related genes, Human disease related genes, Predicted secreted proteins" Hormone "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 50 "ovary: 121.1;testis: 382.6" "Group enriched" "Detected in some" 43 "Leydig cells: 601.2;Peritubular myoid cells: 771.9" "Cell type enhanced" "Detected in single" "leukocyte: 1.2" "Cancer enriched" "Detected in some" 22 "Testicular Germ Cell Tumor (TCGA): 79.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 2.5" "Testis - Leydig cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA028615 Enhanced "Secreted to blood" Hormone NA NA 566000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 57: Testis - Spermatogenesis" "Cluster 15: Non-specific - Transcription" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 94: Gonadal somatic cells - Mixed function" 8 "HPA028615: " "unprognostic (2.84e-2)" "unprognostic (1.66e-2)" "unprognostic (3.01e-1)" "unprognostic (1.42e-1)" "unprognostic (4.66e-2)" "unprognostic (3.80e-1)" "unprognostic (2.72e-1)" "unprognostic (7.57e-3)" "unprognostic (1.92e-1)" "unprognostic (3.61e-2)" INSL4 EPIL ENSG00000120211 "Insulin like 4" Q14641 9 5231419-5235304 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "placenta: 14.9" "Cell type enriched" "Detected in some" 13 "Syncytiotrophoblasts: 5121.6" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "Lung Adenocarcinoma (TCGA): 3.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 7.0" HPA065145 Approved Vesicles "Secreted to blood" Hormone NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 9: Non-specific - Receptor signaling" "Cluster 7: Liver cancer - Metabolism" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 2 Vesicles "HPA065145: " "unprognostic (1.07e-3)" "unprognostic (3.60e-2)" INSL5 ENSG00000172410 "Insulin like 5" Q9Y5Q6 1 66797740-66801276 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 106 "intestine: 115.3" "Cell type enriched" "Detected in some" 460 "Neuroendocrine cells: 4175.8" "Cell type enhanced" "Detected in some" "ependymal cell: 3.7" "Group enriched" "Detected in some" 5 "Prostate Adenocarcinoma (TCGA): 1.1;Rectum Adenocarcinoma (TCGA): 4.4" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enterocytes" "Low region specificity" "Detected in some" "HPA030100, CAB033849" Enhanced "Secreted to blood" Hormone NA NA 38500000 "Cluster 17: Intestine - Digestion" "Cluster 17: Choroid plexus - Cilium" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" "CAB033849: , HPA030100: " "unprognostic (2.40e-2)" "unprognostic (4.35e-1)" "unprognostic (1.88e-3)" INSL6 RIF1 ENSG00000120210 "Insulin like 6" Q9Y581 9 5123880-5185647 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "retina: 6.1;testis: 14.5" "Cell type enhanced" "Detected in many" "Adipocytes: 71.6;Cardiomyocytes: 186.3;cDC: 43.9;Early primary spermatocytes: 50.0;Early spermatids: 142.0;Epicardial cells: 186.5;Late primary spermatocytes: 136.0;Myonuclei: 82.7;Undifferentiated spermatogonia: 64.1" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in single" 23 "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 20.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA021364 Enhanced "Secreted to blood" Hormone NA NA "Cluster 41: Basophils - Unknown function" "Cluster 47: Testis - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 7 "HPA021364: " "unprognostic (2.28e-2)" "unprognostic (1.91e-1)" "unprognostic (9.85e-2)" "unprognostic (4.98e-3)" INSM1 "IA-1, IA1" ENSG00000173404 "INSM transcriptional repressor 1" Q01101 20 20368104-20370949 "Predicted intracellular proteins, Transcription factors" "Cell cycle, Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 14.9;pituitary gland: 27.3" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 74.5;Corticotrophs: 50.1;Lactotrophs: 18.4;Neuroendocrine cells: 292.9;Pancreatic islet cells: 85.1;Thyrotrophs: 18.8" "Cell type enhanced" "Detected in many" "midbrain-derived inhibitory: 11.1;upper rhombic lip: 15.7" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 15.0" "Region enhanced" "Detected in many" "cerebellum: 28.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "lung cancer: 56.0;Neuroblastoma: 15.3" "Adrenal gland - Adrenal medulla cells, Pancreas - Alpha cells, Pancreas - Beta cells, Pituitary gland - Corticotropes, Stomach - Gastric enteroendocrine cells, Testis - Spermatogonia, Thyroid gland - Parafollicular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" 3 "unprognostic (1.42e-1)" "unprognostic (2.27e-2)" "unprognostic (2.54e-2)" "unprognostic (1.55e-3)" "unprognostic (2.67e-2)" "unprognostic (2.32e-1)" "unprognostic (7.17e-2)" "unprognostic (5.08e-2)" "unprognostic (1.25e-1)" "unprognostic (7.91e-2)" "unprognostic (3.03e-2)" "unprognostic (4.34e-3)" "unprognostic (1.83e-1)" "unprognostic (7.03e-2)" "unprognostic (1.66e-1)" "unprognostic (2.00e-1)" INSM2 "IA-6, Mlt1" ENSG00000168348 "INSM transcriptional repressor 2" Q96T92 14 35534164-35537054 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.0;retina: 2.5" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 1.0;Brain inhibitory neurons: 1.5;Breast myoepithelial cells: 2.6;Cone photoreceptor cells: 4.1;Early primary spermatocytes: 5.1;Gastric chief cells: 1.1;Other brain neurons: 3.0;Retinal ganglion cells: 3.9;Retinal horizontal cells: 2.0;Rod photoreceptor cells: 4.2" "Cell type enhanced" "Detected in some" "mammillary body: 10.7;midbrain-derived inhibitory: 5.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 18 "Neuroblastoma: 49.9" "Adrenal gland - Adrenal medulla cells" "Region enhanced" "Detected in single" "hypothalamus: 1.1" "Low region specificity" "Detected in some" "HPA044885, HPA051925" Uncertain Approved Nucleoplasm NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 82: Dendritic cells - Antigen presentation" Nucleoplasm "HPA044885: , HPA051925: " "potential prognostic favorable (7.51e-4)" INSR CD220 ENSG00000171105 "Insulin receptor" P06213 19 7112255-7294414 "CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Carbohydrate metabolism" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Diabetes mellitus, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreatic acinar cells: 1376.5;Peritubular myoid cells: 827.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 8 "dendritic cells: 9.8;granulocytes: 5.9;monocytes: 12.6" "Cancer enhanced" "Detected in all" "Myeloma: 24.6" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036302, HPA036303" Uncertain Approved "Vesicles,Plasma membrane,Primary cilium transition zone,Centriolar satellite,Basal body" NA Yes 130000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 70: Non-specific - Protein processing" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 104 "Vesicles, Plasma membrane" "Primary cilium transition zone, Centriolar satellite, Basal body" "HPA036302: , HPA036303: " "unprognostic (1.21e-2)" "unprognostic (2.45e-1)" "unprognostic (1.04e-1)" "unprognostic (4.41e-1)" "unprognostic (2.63e-1)" "unprognostic (2.03e-2)" "unprognostic (2.46e-1)" "unprognostic (4.55e-1)" "unprognostic (1.04e-1)" "unprognostic (1.14e-1)" "validated prognostic favorable (5.63e-8)" "validated prognostic favorable (5.67e-5)" "unprognostic (2.44e-1)" "unprognostic (1.13e-1)" "unprognostic (1.08e-1)" "unprognostic (2.10e-1)" "unprognostic (3.91e-2)" "unprognostic (9.70e-2)" "potential prognostic favorable (2.02e-4)" "unprognostic (2.30e-1)" "unprognostic (3.88e-2)" "unprognostic (6.86e-2)" "unprognostic (2.16e-2)" "unprognostic (1.41e-1)" "unprognostic (4.40e-1)" "unprognostic (2.01e-1)" "unprognostic (2.55e-2)" "unprognostic (1.14e-2)" "unprognostic (2.26e-1)" "unprognostic (1.71e-1)" "unprognostic (1.29e-1)" INSRR IRR ENSG00000027644 "Insulin receptor related receptor" P14616 1 156840063-156859117 "Enzymes, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 3.8;testis: 1.9" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 10.6;Decidual stromal cells: 11.9;Early primary spermatocytes: 24.6;Fibro-adipogenic progenitors: 14.9;Neuroendocrine cells: 8.9;Other brain neurons: 13.7;Renal collecting duct intercalated cells: 37.0;Retinal bipolar cells: 35.2;Retinal ganglion cells: 19.3;Sertoli cells: 10.1" "Group enriched" "Detected in some" 6 "fibroblast: 15.9;lower rhombic lip: 41.2" "Cancer enhanced" "Detected in single" "Kidney Chromophobe (TCGA): 1.0" "Region enhanced" "Detected in many" "pons: 31.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 8 "Neuroblastoma: 7.5" "Adrenal gland - Adrenal medulla cells, Kidney - Intercalated cells, Skeletal muscle - Fibroblasts" "Not detected" "Not detected" "Not detected" "Not detected" HPA025285 Uncertain NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 49: Hindbrain - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 33 "HPA025285: " "unprognostic (3.70e-2)" INSYN1 "C15orf59, LOC388135, MGC131524" ENSG00000205363 "Inhibitory synaptic factor 1" Q2T9L4 15 73735458-73753351 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 45.0;heart muscle: 41.8" "Cell type enhanced" "Detected in some" "Astrocytes: 18.1;Bergmann glia: 32.2;Brain excitatory neurons: 8.2;Brain inhibitory neurons: 14.1;Epididymal clear cells: 8.2;Epididymal efferent duct absorptive cells: 9.5;Müller glia: 7.7;Oligodendrocyte progenitor cells: 7.3;Other brain neurons: 10.3;Podocytes: 19.4;Renal collecting duct intercalated cells: 12.0;Retinal amacrine cells: 11.8;Retinal bipolar cells: 8.2" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in many" 8 "Kidney Chromophobe (TCGA): 156.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Kidney - Intercalated cells, Pancreas - Beta cells, Pituitary gland - Thyrotropes, Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041563 Approved Approved Nucleoplasm,Cytosol No NA "Cluster 35: Non-specific - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 27: Breast cancer - Unknown function" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" 18 "Nucleoplasm, Cytosol" "HPA041563: " "unprognostic (2.75e-1)" "unprognostic (8.98e-2)" "unprognostic (1.09e-1)" "unprognostic (2.77e-1)" "unprognostic (9.48e-3)" "unprognostic (2.06e-1)" "unprognostic (8.46e-2)" "unprognostic (7.59e-3)" "potential prognostic favorable (5.45e-6)" "unprognostic (2.27e-3)" "unprognostic (2.52e-1)" "unprognostic (7.44e-2)" "unprognostic (1.30e-1)" "unprognostic (1.35e-1)" "potential prognostic favorable (1.47e-4)" "unprognostic (3.25e-2)" "unprognostic (3.02e-2)" "unprognostic (2.39e-1)" "unprognostic (4.34e-2)" "unprognostic (3.21e-2)" "unprognostic (1.49e-1)" INSYN2A "C10orf141, FAM196A, FLJ45557, INSYN2" ENSG00000188916 "Inhibitory synaptic factor 2A" Q6ZSG2 10 127135426-127196591 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.5;retina: 1.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 79.7;Epicardial cells: 234.2;Fibro-adipogenic progenitors: 78.8;Leydig cells: 82.6;Peritubular myoid cells: 82.9;Retinal bipolar cells: 67.0" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in some" 13 "Breast Invasive Carcinoma (TCGA): 5.0;Glioblastoma Multiforme (TCGA): 6.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "thyroid cancer: 1.1" "Pituitary gland - Gonadotropes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA035898, HPA035899" Uncertain NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 3 "HPA035898: , HPA035899: " "unprognostic (1.18e-1)" "unprognostic (9.50e-2)" "unprognostic (3.21e-1)" "unprognostic (2.75e-2)" "unprognostic (1.07e-1)" "unprognostic (6.51e-3)" INSYN2B "C5orf57, FAM196B" ENSG00000204767 "Inhibitory synaptic factor family member 2B" A6NMK8 5 169861303-169980495 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.1;breast: 6.4;salivary gland: 4.9" "Cell type enhanced" "Detected in many" "B-cells: 47.0;Bergmann glia: 48.0;Brain inhibitory neurons: 50.4;cDC: 88.1;Epicardial cells: 50.0;Hematopoietic stem cells: 45.6;Macrophages: 67.3;Mast cells: 49.6;Medullary thymic epithelial cells: 57.6;Microglia: 63.3;Oligodendrocytes: 143.2;Other brain neurons: 41.4;Retinal pigment epithelial cells: 196.1" "Cell type enhanced" "Detected in many" "midbrain-derived inhibitory: 185.6" "Cancer enhanced" "Detected in single" "Kidney Renal Clear Cell Carcinoma (TCGA): 1.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 9.1" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary gland ductal cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA047227 Uncertain NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 72: Neuronal - Signal transduction" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "HPA047227: " "unprognostic (1.40e-1)" "unprognostic (3.36e-2)" "potential prognostic favorable (7.04e-5)" "unprognostic (1.02e-3)" "unprognostic (1.76e-3)" INTS1 "DKFZp586J0619, INT1, KIAA1440, NET28" ENSG00000164880 "Integrator complex subunit 1" Q8N201 7 1470277-1504389 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021658, HPA053009" Approved Approved Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 24: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 65: Non-specific - Cell growth & division" 64 Nucleoplasm "HPA021658: , HPA053009: " "unprognostic (3.14e-1)" "unprognostic (4.41e-2)" "unprognostic (6.35e-2)" "unprognostic (1.98e-3)" "unprognostic (4.26e-2)" "unprognostic (1.43e-1)" "unprognostic (5.35e-1)" "unprognostic (1.03e-1)" "unprognostic (3.34e-1)" "unprognostic (7.78e-3)" "unprognostic (1.18e-2)" "unprognostic (6.16e-2)" "unprognostic (1.62e-2)" "potential prognostic unfavorable (3.48e-6)" "unprognostic (3.02e-3)" "unprognostic (1.01e-3)" "unprognostic (1.31e-2)" "unprognostic (1.23e-1)" "unprognostic (8.07e-2)" "unprognostic (6.97e-3)" "unprognostic (1.61e-1)" "unprognostic (2.71e-3)" "unprognostic (1.90e-3)" "unprognostic (1.00e-1)" "unprognostic (1.95e-2)" "unprognostic (3.15e-2)" "unprognostic (4.01e-1)" "unprognostic (3.19e-1)" "unprognostic (2.12e-1)" "unprognostic (9.56e-2)" "unprognostic (1.96e-1)" INTS10 "C8orf35, FLJ10569, INT10" ENSG00000104613 "Integrator complex subunit 10" Q9NVR2 8 19817391-19852083 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA039129, HPA050570" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 11: T-cells - Unknown function" "Cluster 36: Brain & Liver - Signaling" "Cluster 31: Non-specific - Transcription" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 89: Adipocytes - Lipid metabolism" 31 Cytosol Nucleoplasm "HPA039129: , HPA050570: " "unprognostic (1.94e-2)" "unprognostic (2.58e-1)" "unprognostic (6.95e-2)" "unprognostic (5.88e-2)" "unprognostic (1.23e-3)" "unprognostic (1.86e-2)" "unprognostic (2.34e-1)" "unprognostic (1.89e-2)" "unprognostic (8.41e-3)" "unprognostic (2.37e-2)" "unprognostic (2.49e-2)" "unprognostic (1.65e-2)" "unprognostic (2.56e-1)" "unprognostic (6.19e-2)" "unprognostic (4.87e-2)" "unprognostic (6.86e-3)" "unprognostic (5.57e-2)" "unprognostic (7.75e-2)" "unprognostic (9.65e-2)" "unprognostic (2.37e-1)" "unprognostic (2.38e-2)" "unprognostic (1.75e-1)" "unprognostic (9.51e-3)" "unprognostic (2.30e-1)" "unprognostic (1.58e-2)" "unprognostic (1.27e-1)" "unprognostic (3.44e-1)" "unprognostic (1.15e-2)" "unprognostic (2.79e-1)" "unprognostic (6.08e-2)" "unprognostic (3.83e-2)" INTS11 "CPSF3L, CPSF73L, FLJ20542, INT11, RC-68" ENSG00000127054 "Integrator complex subunit 11" Q5TA45 1 1311585-1324687 "Essential proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 164.5;Late primary spermatocytes: 196.0;Late spermatids: 559.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028379, HPA029025" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 24: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 46 Cytosol Nucleoplasm "HPA028379: , HPA029025: " "unprognostic (2.37e-2)" "unprognostic (2.56e-1)" "unprognostic (3.29e-1)" "unprognostic (6.58e-2)" "unprognostic (1.13e-1)" "unprognostic (1.06e-2)" "unprognostic (2.34e-2)" "unprognostic (1.58e-3)" "unprognostic (3.37e-1)" "potential prognostic favorable (8.58e-4)" "unprognostic (3.82e-1)" "unprognostic (2.46e-2)" "potential prognostic unfavorable (5.03e-4)" "unprognostic (1.74e-1)" "unprognostic (2.10e-3)" "unprognostic (3.80e-2)" "unprognostic (1.03e-1)" "unprognostic (4.10e-2)" "unprognostic (3.64e-2)" "unprognostic (7.04e-2)" "unprognostic (1.97e-1)" "unprognostic (6.21e-2)" "unprognostic (1.91e-1)" "unprognostic (3.03e-2)" "unprognostic (1.33e-1)" "unprognostic (2.65e-1)" "unprognostic (1.48e-1)" "unprognostic (1.43e-1)" "unprognostic (4.00e-2)" INTS12 "INT12, PHF22, SBBI22" ENSG00000138785 "Integrator complex subunit 12" Q96CB8 4 105682627-105895986 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 190.3;Podocytes: 703.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035772, HPA041814" Approved Approved "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 57: Podocytes - Glomerular filtration" 41 "Nucleoplasm, Cytosol" "Nuclear bodies, Plasma membrane" "HPA035772: , HPA041814: " "unprognostic (1.23e-2)" "unprognostic (3.43e-2)" "unprognostic (1.98e-3)" "unprognostic (7.27e-2)" "unprognostic (1.75e-3)" "unprognostic (2.29e-1)" "unprognostic (2.47e-1)" "unprognostic (1.41e-1)" "unprognostic (3.64e-3)" "unprognostic (2.08e-3)" "potential prognostic favorable (1.85e-6)" "unprognostic (1.32e-2)" "unprognostic (3.15e-2)" "potential prognostic unfavorable (1.36e-5)" "unprognostic (1.48e-1)" "unprognostic (9.15e-2)" "unprognostic (1.49e-2)" "unprognostic (1.37e-1)" "unprognostic (1.55e-1)" "unprognostic (1.59e-1)" "unprognostic (4.51e-1)" "unprognostic (3.19e-2)" "unprognostic (2.70e-2)" "unprognostic (3.90e-2)" "unprognostic (2.13e-3)" "unprognostic (3.88e-2)" "unprognostic (1.80e-1)" "unprognostic (2.99e-1)" "unprognostic (3.24e-1)" "unprognostic (1.34e-1)" "unprognostic (1.25e-1)" INTS13 "ASUN, C12orf11, FLJ10637, Mat89Bb, NET48, SPATA30" ENSG00000064102 "Integrator complex subunit 13" Q9NVM9 12 26905181-26938326 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Parietal cells: 95.5" "Cell type enhanced" "Detected in all" "oligodendrocyte: 94.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039543, HPA040109, HPA073020" Uncertain Supported "Nucleoplasm,Nuclear bodies,Vesicles" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 38: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 18 Nucleoplasm "Nuclear bodies, Vesicles" "HPA039543: , HPA040109: , HPA073020: " "unprognostic (1.18e-1)" "unprognostic (1.48e-1)" "unprognostic (3.96e-2)" "unprognostic (5.13e-2)" "unprognostic (1.71e-1)" "unprognostic (1.06e-1)" "unprognostic (5.89e-3)" "unprognostic (1.21e-2)" "unprognostic (6.48e-3)" "unprognostic (9.28e-2)" "unprognostic (9.50e-2)" "unprognostic (1.20e-2)" "potential prognostic unfavorable (2.04e-13)" "potential prognostic unfavorable (5.65e-4)" "unprognostic (6.32e-3)" "unprognostic (1.76e-2)" "unprognostic (1.92e-1)" "unprognostic (1.34e-1)" "unprognostic (2.79e-1)" "validated prognostic unfavorable (2.67e-5)" "validated prognostic unfavorable (2.85e-5)" "unprognostic (8.94e-3)" "unprognostic (5.41e-3)" "unprognostic (1.93e-1)" "unprognostic (3.60e-2)" "unprognostic (2.45e-1)" "unprognostic (2.00e-1)" "unprognostic (1.33e-1)" "unprognostic (1.81e-1)" INTS14 "C15orf44, DKFZP564O1664, VWA9" ENSG00000138614 "Integrator complex subunit 14" Q96SY0 15 65578753-65611289 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040255, HPA040651" Approved Approved "Nucleoplasm,Nuclear membrane,Nuclear bodies,Mitochondria" No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 22: Epididymis - Mixed function" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 58: Non-specific - Nuclear processes" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 40 "Nucleoplasm, Nuclear bodies, Mitochondria" "Nuclear membrane" "HPA040255: , HPA040651: " "unprognostic (2.45e-2)" "unprognostic (4.38e-2)" "unprognostic (3.85e-2)" "unprognostic (3.31e-1)" "unprognostic (2.19e-1)" "unprognostic (1.93e-1)" "unprognostic (7.11e-2)" "unprognostic (1.71e-2)" "unprognostic (1.06e-2)" "validated prognostic favorable (1.29e-7)" "validated prognostic favorable (1.75e-4)" "unprognostic (1.14e-1)" "unprognostic (6.27e-2)" "unprognostic (1.01e-1)" "unprognostic (1.08e-2)" "unprognostic (5.79e-2)" "unprognostic (1.65e-1)" "unprognostic (2.03e-1)" "unprognostic (3.86e-1)" "unprognostic (4.16e-2)" "unprognostic (2.03e-2)" "unprognostic (7.65e-2)" "unprognostic (2.30e-2)" "unprognostic (7.95e-2)" "unprognostic (5.23e-2)" "unprognostic (6.40e-2)" "unprognostic (5.35e-2)" "unprognostic (2.19e-1)" "unprognostic (4.66e-3)" INTS15 "C7orf26, MGC2718" ENSG00000146576 "Integrator complex subunit 15" Q96N11 7 6590021-6608726 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042899, HPA052175" Uncertain Approved "Nucleoplasm,Mitotic spindle,Cytosol" Yes NA "Cluster 25: Non-specific - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 20: Non-specific - Transcription regulation" 6 Nucleoplasm "Mitotic spindle, Cytosol" "HPA042899: , HPA052175: " "unprognostic (1.14e-2)" "unprognostic (1.54e-2)" "unprognostic (9.21e-2)" "unprognostic (6.48e-2)" "unprognostic (2.16e-2)" "unprognostic (1.22e-1)" "unprognostic (2.57e-2)" "unprognostic (1.85e-1)" "unprognostic (4.80e-2)" "unprognostic (4.17e-2)" "unprognostic (2.75e-1)" "unprognostic (6.01e-2)" "unprognostic (2.79e-2)" "unprognostic (1.12e-2)" "unprognostic (2.59e-2)" "unprognostic (4.95e-1)" "unprognostic (1.64e-1)" "unprognostic (1.45e-2)" "unprognostic (6.03e-2)" "unprognostic (6.47e-2)" "unprognostic (1.59e-3)" "potential prognostic favorable (1.06e-4)" "unprognostic (4.97e-2)" "unprognostic (7.16e-2)" "unprognostic (9.86e-2)" "unprognostic (1.99e-1)" "unprognostic (3.17e-1)" "unprognostic (2.85e-1)" "unprognostic (4.32e-2)" "unprognostic (6.68e-3)" "unprognostic (2.11e-1)" INTS2 "INT2, KIAA1287" ENSG00000108506 "Integrator complex subunit 2" Q9H0H0 17 61865367-61928016 "Essential proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049524 Uncertain NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 9: Non-specific - Receptor signaling" "Cluster 27: Breast cancer - Unknown function" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 39 "HPA049524: " "unprognostic (1.04e-1)" "unprognostic (3.26e-3)" "unprognostic (1.11e-1)" "unprognostic (8.61e-3)" "unprognostic (3.18e-2)" "unprognostic (3.33e-1)" "unprognostic (3.30e-1)" "unprognostic (6.66e-2)" "unprognostic (2.61e-1)" "unprognostic (1.16e-2)" "potential prognostic favorable (3.35e-5)" "unprognostic (5.01e-3)" "unprognostic (5.03e-1)" "unprognostic (3.82e-3)" "unprognostic (2.22e-3)" "unprognostic (2.74e-3)" "unprognostic (3.16e-3)" "unprognostic (4.35e-1)" "unprognostic (7.02e-3)" "unprognostic (6.32e-2)" "unprognostic (9.65e-2)" "unprognostic (1.57e-1)" "unprognostic (1.44e-1)" "unprognostic (2.82e-1)" "unprognostic (6.41e-3)" "unprognostic (1.92e-3)" "unprognostic (6.70e-2)" "unprognostic (3.94e-2)" "unprognostic (1.84e-1)" "unprognostic (6.10e-2)" "unprognostic (6.27e-2)" INTS3 "C1orf60, FLJ21919, INT3, SOSS-A" ENSG00000143624 "Integrator complex subunit 3" Q68E01 1 153728050-153774808 "Essential proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 77.6;Bergmann glia: 58.3;Brain excitatory neurons: 40.3;Brain inhibitory neurons: 41.6;Choroid plexus epithelial cells: 43.4;Distal convoluted tubule cells: 37.7;Ependymal cells: 63.3;Loop of henle epithelial cells: 60.1;Microglia: 41.3;Oligodendrocyte progenitor cells: 37.0;Oligodendrocytes: 41.0;Other brain neurons: 36.4;Papillary tip epithelial cells: 40.9;Podocytes: 100.1;Proximal tubule cells: 83.2;Renal collecting duct intercalated cells: 50.6;Renal collecting duct principal cells: 48.0;Renal connecting tubule cells: 41.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074391 Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 64: Non-specific - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 45: Non-specific - Nuclear processes" "Cluster 102: Non-specific - Mixed function" 50 Nucleoli Nucleoplasm "HPA074391: " "unprognostic (2.51e-2)" "unprognostic (4.01e-2)" "unprognostic (3.06e-2)" "unprognostic (6.67e-2)" "unprognostic (4.42e-1)" "unprognostic (1.07e-1)" "unprognostic (2.09e-1)" "unprognostic (4.48e-2)" "unprognostic (1.18e-2)" "unprognostic (5.32e-3)" "unprognostic (2.19e-3)" "unprognostic (1.83e-1)" "unprognostic (2.84e-1)" "unprognostic (4.72e-2)" "unprognostic (1.30e-1)" "unprognostic (3.85e-2)" "unprognostic (3.11e-1)" "unprognostic (6.50e-2)" "unprognostic (2.09e-2)" "unprognostic (1.69e-1)" "unprognostic (3.43e-2)" "unprognostic (1.50e-1)" "unprognostic (2.81e-2)" "unprognostic (2.96e-1)" "unprognostic (1.59e-1)" "unprognostic (1.09e-1)" "unprognostic (6.07e-2)" "unprognostic (3.64e-2)" "unprognostic (8.99e-2)" "unprognostic (1.18e-2)" "unprognostic (2.10e-1)" INTS4 "INT4, MGC16733, MST093" ENSG00000149262 "Integrator complex subunit 4" Q96HW7 11 77874418-77994715 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 146.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042378 Uncertain Supported "Nucleoli rim" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 61: Non-specific - Transcription" "Cluster 30: White matter - Myelination" "Cluster 24: Non-specific - Unknown function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 44 "Nucleoli rim" "HPA042378: " "unprognostic (1.92e-1)" "unprognostic (6.11e-2)" "unprognostic (2.93e-2)" "potential prognostic favorable (9.84e-4)" "unprognostic (1.77e-1)" "unprognostic (9.81e-2)" "unprognostic (1.88e-1)" "potential prognostic favorable (5.03e-4)" "unprognostic (2.35e-1)" "unprognostic (8.59e-2)" "unprognostic (4.95e-2)" "unprognostic (1.94e-1)" "unprognostic (5.46e-2)" "potential prognostic unfavorable (1.23e-6)" "unprognostic (2.32e-1)" "unprognostic (3.57e-2)" "potential prognostic unfavorable (9.76e-4)" "unprognostic (2.55e-2)" "unprognostic (1.64e-1)" "unprognostic (6.99e-2)" "unprognostic (2.88e-2)" "unprognostic (1.68e-2)" "potential prognostic unfavorable (3.02e-4)" "unprognostic (1.11e-1)" "unprognostic (3.57e-3)" "unprognostic (3.26e-2)" "unprognostic (3.63e-2)" "unprognostic (2.95e-1)" "unprognostic (3.31e-1)" "unprognostic (3.24e-2)" "unprognostic (4.36e-1)" INTS5 "INT5, KIAA1698" ENSG00000185085 "Integrator complex subunit 5" Q6P9B9 11 62646848-62653302 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 25.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046181, HPA056915" Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 1: T-cells - Unknown function" "Cluster 49: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 36 Nucleoplasm Cytosol "HPA046181: , HPA056915: " "unprognostic (1.81e-1)" "unprognostic (5.46e-2)" "unprognostic (2.85e-1)" "unprognostic (1.81e-1)" "unprognostic (2.74e-1)" "unprognostic (3.82e-2)" "unprognostic (3.29e-2)" "unprognostic (2.08e-1)" "unprognostic (5.96e-2)" "unprognostic (3.92e-2)" "potential prognostic favorable (7.11e-6)" "unprognostic (4.85e-2)" "unprognostic (1.38e-1)" "unprognostic (3.38e-3)" "unprognostic (1.61e-1)" "unprognostic (7.73e-2)" "potential prognostic unfavorable (1.32e-4)" "unprognostic (3.43e-2)" "unprognostic (7.08e-3)" "unprognostic (7.35e-2)" "unprognostic (1.97e-2)" "unprognostic (1.20e-1)" "unprognostic (6.13e-2)" "unprognostic (7.57e-2)" "unprognostic (1.48e-2)" "unprognostic (2.27e-2)" "unprognostic (2.46e-1)" "unprognostic (4.04e-2)" "unprognostic (4.25e-2)" "unprognostic (2.10e-1)" "unprognostic (8.64e-2)" INTS6 "DBI-1, DDX26, DDX26A, DICE1, HDB, INT6, Notchl2" ENSG00000102786 "Integrator complex subunit 6" Q9UL03 13 51354077-51454264 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epididymal basal cells: 696.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001552, HPA001846" Supported Supported "Nucleoplasm,Actin filaments" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 57: Testis - Spermatogenesis" "Cluster 55: Non-specific - Transcription" "Cluster 19: Non-specific - Unknown function" "Cluster 20: Non-specific - Transcription regulation" 37 Nucleoplasm "Actin filaments" "HPA001552: , HPA001846: " "unprognostic (4.26e-2)" "unprognostic (5.58e-2)" "unprognostic (1.02e-1)" "unprognostic (1.08e-2)" "unprognostic (3.96e-1)" "unprognostic (3.44e-1)" "unprognostic (1.98e-2)" "unprognostic (1.28e-3)" "unprognostic (6.42e-2)" "unprognostic (2.31e-2)" "unprognostic (1.76e-3)" "unprognostic (6.29e-3)" "unprognostic (1.26e-1)" "unprognostic (1.98e-1)" "unprognostic (1.72e-1)" "unprognostic (1.42e-2)" "unprognostic (1.28e-3)" "unprognostic (3.23e-1)" "unprognostic (2.50e-1)" "unprognostic (8.15e-3)" "unprognostic (1.38e-2)" "unprognostic (6.99e-2)" "potential prognostic unfavorable (3.70e-4)" "unprognostic (7.84e-2)" "unprognostic (9.37e-2)" "unprognostic (1.43e-1)" "unprognostic (4.97e-2)" "unprognostic (2.44e-2)" "unprognostic (1.93e-1)" "unprognostic (2.62e-1)" "unprognostic (1.26e-1)" INTS6L "DDX26B, FLJ41215" ENSG00000165359 "Integrator complex subunit 6 like" Q5JSJ4 X 135520659-135582510 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ependymal cells: 146.3;Sertoli cells: 239.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001552, HPA013200, HPA013335, HPA030747" Uncertain Approved "Nuclear bodies,Centrosome,Mitochondria" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 39: Testis - Nuclear processes" "Cluster 2: Neurons - Nucleosome" "Cluster 36: Non-specific - mRNA processing" "Cluster 20: Non-specific - Transcription regulation" 1 Centrosome "Nuclear bodies, Mitochondria" "HPA001552: , HPA013200: , HPA013335: , HPA030747: " "unprognostic (1.21e-1)" "unprognostic (4.33e-2)" "potential prognostic favorable (7.19e-4)" "unprognostic (2.56e-1)" "unprognostic (1.83e-1)" "unprognostic (2.47e-1)" "unprognostic (1.06e-3)" "unprognostic (5.45e-3)" "unprognostic (7.87e-3)" "unprognostic (5.83e-2)" "unprognostic (1.71e-2)" "unprognostic (3.80e-2)" "unprognostic (6.20e-2)" "unprognostic (9.87e-2)" "unprognostic (5.81e-2)" "unprognostic (9.16e-2)" "unprognostic (1.69e-3)" "unprognostic (4.32e-2)" "unprognostic (1.36e-3)" "potential prognostic unfavorable (1.01e-4)" "unprognostic (3.47e-1)" "unprognostic (1.47e-1)" "unprognostic (4.74e-2)" "unprognostic (3.14e-1)" "unprognostic (1.48e-1)" "unprognostic (4.39e-1)" "unprognostic (1.80e-2)" INTS7 "C1orf73, DKFZP434B168, INT7" ENSG00000143493 "Integrator complex subunit 7" Q9NVH2 1 211940399-212035557 "Essential proteins, Predicted intracellular proteins" "DNA damage" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Megakaryocyte-Erythroid progenitors: 108.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072611 Supported "Nuclear bodies" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 39: Testis - Nuclear processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 15 "Nuclear bodies" "HPA072611: " "unprognostic (1.01e-1)" "unprognostic (2.98e-2)" "unprognostic (3.29e-1)" "unprognostic (2.39e-2)" "unprognostic (1.02e-2)" "unprognostic (3.29e-2)" "unprognostic (7.20e-2)" "unprognostic (3.57e-3)" "unprognostic (1.25e-1)" "unprognostic (2.09e-3)" "unprognostic (8.06e-2)" "unprognostic (7.39e-2)" "potential prognostic unfavorable (5.48e-4)" "unprognostic (7.98e-3)" "unprognostic (4.95e-2)" "potential prognostic unfavorable (1.84e-6)" "unprognostic (1.50e-2)" "unprognostic (1.20e-1)" "unprognostic (3.43e-1)" "unprognostic (4.68e-3)" "unprognostic (2.72e-2)" "unprognostic (1.12e-1)" "unprognostic (2.96e-2)" "unprognostic (1.64e-1)" "unprognostic (1.31e-1)" "unprognostic (1.64e-1)" "unprognostic (2.14e-3)" "unprognostic (1.37e-1)" "unprognostic (4.82e-2)" "unprognostic (3.60e-1)" "unprognostic (2.05e-1)" INTS8 "C8orf52, FLJ20530, INT8, MGC131633" ENSG00000164941 "Integrator complex subunit 8" Q75QN2 8 94813311-94881746 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Retinal horizontal cells: 164.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057299 Approved Approved Nucleoplasm Yes No "Cluster 21: Neutrophils - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 40: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 19 Nucleoplasm "HPA057299: " "unprognostic (1.38e-1)" "unprognostic (1.50e-2)" "unprognostic (2.56e-2)" "unprognostic (2.79e-2)" "unprognostic (2.17e-1)" "unprognostic (4.71e-2)" "unprognostic (2.33e-1)" "unprognostic (1.35e-2)" "unprognostic (1.20e-2)" "potential prognostic unfavorable (1.27e-5)" "unprognostic (1.14e-1)" "unprognostic (6.40e-2)" "potential prognostic unfavorable (2.06e-4)" "potential prognostic unfavorable (1.86e-6)" "unprognostic (1.08e-2)" "potential prognostic unfavorable (9.44e-4)" "unprognostic (9.29e-2)" "unprognostic (2.28e-1)" "unprognostic (2.07e-1)" "potential prognostic unfavorable (1.40e-5)" "unprognostic (5.60e-2)" "unprognostic (2.94e-2)" "unprognostic (2.46e-3)" "unprognostic (2.03e-1)" "unprognostic (6.00e-2)" "unprognostic (6.73e-2)" "unprognostic (1.68e-2)" "unprognostic (2.01e-1)" "unprognostic (1.77e-1)" "unprognostic (7.57e-2)" "unprognostic (3.75e-2)" INTS9 "CPSF2L, FLJ10871, RC-74" ENSG00000104299 "Integrator complex subunit 9" Q9NV88 8 28767661-28890242 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 184.0;Rod photoreceptor cells: 136.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051615, HPA066822" Enhanced Nucleoplasm Yes No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 39: Testis - Nuclear processes" "Cluster 21: Non-specific - Metabolism" "Cluster 40: Non-specific - Unknown function" "Cluster 18: Adrenal cortex cells - Steroidogensis" 38 Nucleoplasm "HPA051615: , HPA066822: " "unprognostic (1.57e-2)" "unprognostic (2.42e-2)" "unprognostic (2.13e-1)" "unprognostic (2.27e-1)" "unprognostic (2.18e-2)" "unprognostic (1.53e-2)" "unprognostic (2.30e-1)" "potential prognostic favorable (1.84e-4)" "unprognostic (2.52e-2)" "unprognostic (2.15e-2)" "unprognostic (1.86e-3)" "unprognostic (4.03e-2)" "unprognostic (5.75e-2)" "unprognostic (1.19e-2)" "unprognostic (6.94e-2)" "unprognostic (9.03e-2)" "unprognostic (1.91e-1)" "unprognostic (9.56e-3)" "unprognostic (1.68e-1)" "unprognostic (5.95e-2)" "unprognostic (9.61e-2)" "unprognostic (2.21e-2)" "unprognostic (1.01e-1)" "unprognostic (1.85e-2)" "unprognostic (1.89e-2)" "unprognostic (1.86e-2)" "unprognostic (1.82e-2)" "unprognostic (9.46e-2)" "unprognostic (3.54e-1)" "unprognostic (7.93e-2)" "unprognostic (4.34e-2)" INTU "CPLANE4, KIAA1284, PDZD6, PDZK6" ENSG00000164066 "Inturned planar cell polarity protein" Q9ULD6 4 127623271-127726737 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Developmental protein" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 12.2" "Cell type enhanced" "Detected in many" "Astrocytes: 290.9;Choroid plexus epithelial cells: 179.1;Ependymal cells: 422.4;Pituicytes/FSCs: 196.4;Thyrotrophs: 190.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 1.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Lung - Respiratory ciliated cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036714, HPA036715" Approved Approved "Vesicles,Basal body,Cytosol" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 9: Non-specific - Receptor signaling" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 34: Ciliated cells - Cilia assembly & function" 3 "Basal body" "Vesicles, Cytosol" "HPA036714: , HPA036715: " "unprognostic (1.96e-1)" "unprognostic (1.92e-1)" "unprognostic (8.79e-2)" "unprognostic (9.50e-3)" "potential prognostic unfavorable (9.02e-4)" "unprognostic (6.39e-2)" "unprognostic (3.80e-1)" "unprognostic (1.97e-2)" "unprognostic (1.86e-2)" "potential prognostic unfavorable (3.42e-4)" "unprognostic (1.22e-1)" "unprognostic (1.12e-2)" "unprognostic (6.38e-3)" "unprognostic (2.71e-1)" "unprognostic (1.13e-1)" "unprognostic (2.29e-2)" "unprognostic (2.27e-1)" "unprognostic (2.96e-3)" "unprognostic (5.24e-2)" "unprognostic (9.23e-2)" "unprognostic (2.28e-1)" "unprognostic (9.40e-3)" "unprognostic (3.37e-2)" "unprognostic (7.01e-3)" "unprognostic (2.65e-1)" "unprognostic (8.87e-2)" "unprognostic (1.34e-1)" "unprognostic (6.91e-2)" "unprognostic (3.83e-1)" INVS NPHP2 ENSG00000119509 Inversin Q9Y283 9 100099243-100302175 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Wnt signaling pathway" "Calmodulin-binding, Developmental protein" "Ciliopathy, Disease variant, Nephronophthisis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049994 Approved "Primary cilium,Centrosome,Basal body,Cytosol" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 61: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Transcription" 4 "Primary cilium, Cytosol" "Centrosome, Basal body" "HPA049994: " "unprognostic (1.80e-1)" "unprognostic (2.10e-2)" "unprognostic (4.75e-2)" "unprognostic (1.52e-2)" "unprognostic (1.30e-1)" "unprognostic (5.35e-2)" "unprognostic (1.64e-1)" "unprognostic (3.26e-3)" "unprognostic (5.45e-2)" "unprognostic (5.62e-2)" "validated prognostic favorable (4.48e-7)" "validated prognostic favorable (6.46e-5)" "unprognostic (3.89e-1)" "unprognostic (1.38e-2)" "unprognostic (5.20e-2)" "unprognostic (1.11e-2)" "unprognostic (1.35e-1)" "unprognostic (9.07e-2)" "unprognostic (2.97e-2)" "unprognostic (7.08e-2)" "unprognostic (3.18e-2)" "unprognostic (1.29e-1)" "unprognostic (1.29e-2)" "unprognostic (1.09e-1)" "potential prognostic favorable (9.99e-4)" "unprognostic (2.45e-2)" "unprognostic (3.49e-1)" "unprognostic (4.82e-1)" "unprognostic (2.57e-1)" "unprognostic (2.12e-2)" "unprognostic (9.47e-2)" IP6K1 "IHPK1, KIAA0263" ENSG00000176095 "Inositol hexakisphosphate kinase 1" Q92551 3 49724294-49786542 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 421.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040825 Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 24: Neutrophils - Innate immunity signal integration" 15 "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "HPA040825: " "unprognostic (4.47e-2)" "unprognostic (3.41e-2)" "unprognostic (1.44e-1)" "unprognostic (6.32e-2)" "unprognostic (1.80e-1)" "unprognostic (6.82e-3)" "unprognostic (1.46e-1)" "unprognostic (2.02e-1)" "unprognostic (7.79e-3)" "unprognostic (1.86e-3)" "potential prognostic favorable (3.33e-6)" "unprognostic (2.69e-3)" "unprognostic (3.07e-2)" "unprognostic (1.55e-3)" "unprognostic (3.13e-3)" "unprognostic (2.33e-2)" "unprognostic (1.32e-1)" "unprognostic (2.54e-2)" "unprognostic (1.60e-1)" "unprognostic (1.49e-1)" "unprognostic (2.04e-1)" "unprognostic (1.03e-2)" "unprognostic (1.13e-1)" "unprognostic (1.07e-1)" "unprognostic (1.54e-1)" "unprognostic (2.44e-2)" "unprognostic (1.62e-1)" "unprognostic (3.33e-1)" "unprognostic (1.36e-1)" "unprognostic (1.02e-1)" "unprognostic (4.03e-2)" IP6K2 IHPK2 ENSG00000068745 "Inositol hexakisphosphate kinase 2" Q9UHH9 3 48688003-48740353 "Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Phospholipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007532, HPA070811" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Cell Junctions" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 64: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 13 "Nucleoli fibrillar center" "Nucleoplasm, Cell Junctions" "HPA007532: , HPA070811: " "unprognostic (9.92e-3)" "unprognostic (6.59e-3)" "unprognostic (1.87e-1)" "unprognostic (2.85e-1)" "unprognostic (1.84e-1)" "unprognostic (7.00e-3)" "unprognostic (1.95e-1)" "unprognostic (3.41e-2)" "unprognostic (3.54e-2)" "unprognostic (9.38e-3)" "unprognostic (1.42e-1)" "unprognostic (2.84e-2)" "potential prognostic favorable (2.17e-6)" "unprognostic (2.04e-3)" "unprognostic (2.12e-1)" "unprognostic (4.00e-2)" "unprognostic (2.84e-2)" "unprognostic (4.87e-2)" "unprognostic (3.34e-2)" "unprognostic (3.04e-1)" "unprognostic (2.33e-1)" "unprognostic (2.62e-2)" "unprognostic (1.86e-2)" "unprognostic (6.45e-2)" "unprognostic (2.20e-2)" "unprognostic (2.97e-2)" "unprognostic (7.82e-3)" "unprognostic (2.52e-2)" "unprognostic (2.88e-1)" "unprognostic (1.50e-1)" "unprognostic (3.39e-3)" IP6K3 "IHPK3, INSP6K3" ENSG00000161896 "Inositol hexakisphosphate kinase 3" Q96PC2 6 33721662-33746905 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "skeletal muscle: 290.7;tongue: 77.8" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 70.2;Myonuclei: 112.6;Myosatellite cells: 57.6;Podocytes: 48.5;Proximal tubule cells: 42.6;Thymic myoid cells: 80.2" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 7.7;oligodendrocyte: 26.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Sarcoma: 3.8;testis cancer: 4.9" "Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Spleen - Fibroblasts_2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA053644, HPA062531" Enhanced Approved Nucleoplasm,Cytosol Yes NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 11: White matter - Signal transduction" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 13 Nucleoplasm Cytosol "HPA053644: , HPA062531: " "unprognostic (2.92e-1)" "potential prognostic favorable (1.91e-5)" "unprognostic (4.56e-2)" "unprognostic (1.49e-1)" "unprognostic (1.82e-1)" "unprognostic (2.93e-3)" "unprognostic (4.57e-2)" "unprognostic (3.42e-3)" "unprognostic (4.23e-1)" "unprognostic (1.11e-3)" "unprognostic (7.16e-2)" "unprognostic (2.95e-2)" "unprognostic (1.32e-1)" "unprognostic (2.56e-1)" "unprognostic (1.12e-1)" "unprognostic (4.20e-3)" "unprognostic (7.20e-2)" "unprognostic (6.51e-3)" "unprognostic (4.07e-2)" "unprognostic (1.68e-1)" "unprognostic (2.90e-3)" IPCEF1 "KIAA0403, PIP3-E" ENSG00000074706 "Interaction protein for cytohesin exchange factors 1" Q8WWN9 6 154154496-154356803 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "bone marrow: 15.8;brain: 18.1;lymphoid tissue: 12.6;thyroid gland: 34.0" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 282.9;Loop of henle epithelial cells: 179.4;Microglia: 58.3;Neutrophil progenitors: 67.1;Podocytes: 56.0;Proximal tubule cells: 66.4;Renal collecting duct intercalated cells: 345.5;Renal collecting duct principal cells: 104.9;Renal connecting tubule cells: 298.6;T-cells: 54.0" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 62.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 9 "Leukemia: 6.4;lymphoma: 7.3" "Adrenal gland - T-cells, Breast - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028708, HPA028710" Supported Approved "Nucleoli,Nuclear speckles,Plasma membrane,Cytoplasmic bodies" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 27: Cerebellum - Synaptic function" "Cluster 53: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 11 "Nuclear speckles, Plasma membrane" "Nucleoli, Cytoplasmic bodies" "HPA028708: , HPA028710: " "unprognostic (6.56e-2)" "unprognostic (2.40e-1)" "unprognostic (9.84e-2)" "unprognostic (1.98e-1)" "unprognostic (7.42e-3)" "unprognostic (9.96e-3)" "potential prognostic favorable (6.15e-5)" "unprognostic (3.62e-2)" "unprognostic (8.34e-2)" "unprognostic (6.90e-3)" "unprognostic (1.37e-1)" "unprognostic (2.94e-1)" "unprognostic (1.20e-1)" "unprognostic (8.27e-2)" "unprognostic (5.11e-2)" "unprognostic (9.17e-2)" "unprognostic (4.43e-2)" "unprognostic (1.24e-1)" "unprognostic (1.66e-2)" "unprognostic (1.99e-1)" IPMK ENSG00000151151 "Inositol polyphosphate multikinase" Q8NFU5 10 58191517-58267894 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Phospholipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 16.9" "Cell type enriched" "Detected in many" 4 "Neutrophils: 916.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 3.0" "Group enriched" "Detected in many" 4 "granulocytes: 3.0;monocytes: 1.0" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 26.4" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037837, HPA057542" Uncertain Supported "Nucleoplasm,Basal body" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 76: Non-specific - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 2 Nucleoplasm "Basal body" "HPA037837: , HPA057542: " "unprognostic (1.71e-2)" "unprognostic (4.00e-2)" "unprognostic (3.35e-1)" "unprognostic (6.11e-2)" "unprognostic (6.57e-2)" "unprognostic (2.56e-2)" "unprognostic (1.36e-1)" "potential prognostic favorable (1.21e-4)" "unprognostic (3.09e-2)" "unprognostic (1.13e-2)" "unprognostic (1.82e-2)" "unprognostic (8.03e-2)" "potential prognostic unfavorable (9.58e-4)" "unprognostic (1.42e-3)" "unprognostic (9.21e-2)" "unprognostic (4.64e-3)" "unprognostic (6.46e-2)" "unprognostic (8.77e-3)" "unprognostic (1.01e-2)" "unprognostic (6.00e-2)" "unprognostic (1.43e-2)" "unprognostic (7.83e-2)" "unprognostic (7.41e-3)" "unprognostic (1.32e-1)" "unprognostic (2.32e-2)" "unprognostic (1.35e-1)" "unprognostic (3.43e-1)" "unprognostic (1.60e-1)" "unprognostic (1.85e-1)" "unprognostic (5.45e-3)" "unprognostic (4.20e-1)" IPO11 RanBP11 ENSG00000086200 "Importin 11" Q9UI26 5 62403972-62628582 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Lymphatic endothelial cells: 135.0;Platelets: 132.1;Sertoli cells: 189.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "NK-cell: 22.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065346, HPA067097" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 32: Basophils - Transcription" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 21: Non-specific - Metabolism" "Cluster 59: Leukemia - T-cell receptor" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 19 Nucleoplasm Cytosol "HPA065346: , HPA067097: " "unprognostic (5.24e-1)" "unprognostic (5.98e-2)" "unprognostic (1.10e-1)" "unprognostic (5.63e-3)" "unprognostic (2.70e-2)" "unprognostic (4.73e-2)" "unprognostic (1.39e-1)" "unprognostic (1.86e-1)" "unprognostic (1.48e-1)" "potential prognostic unfavorable (7.43e-4)" "validated prognostic favorable (2.54e-7)" "validated prognostic favorable (8.24e-4)" "unprognostic (1.16e-1)" "potential prognostic unfavorable (4.70e-4)" "unprognostic (5.15e-2)" "unprognostic (1.14e-1)" "unprognostic (3.38e-2)" "unprognostic (1.68e-1)" "unprognostic (2.23e-1)" "unprognostic (2.76e-2)" "potential prognostic unfavorable (6.47e-5)" "unprognostic (1.48e-1)" "potential prognostic unfavorable (1.42e-5)" "unprognostic (1.33e-1)" "unprognostic (2.05e-2)" "unprognostic (5.06e-2)" "unprognostic (1.10e-2)" "unprognostic (6.15e-2)" "unprognostic (1.59e-1)" "unprognostic (2.76e-2)" "unprognostic (3.96e-1)" IPO13 "IMP13, KIAA0724, RANBP13" ENSG00000117408 "Importin 13" O94829 1 43946950-43968022 "Essential proteins, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 121.1" "Cell type enhanced" "Detected in many" "Early spermatids: 49.3;Late primary spermatocytes: 68.8;Late spermatids: 157.4;Oligodendrocytes: 83.1" "Cell type enhanced" "Detected in all" "oligodendrocyte: 104.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB070425 Uncertain NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 37: Non-specific - mRNA processing" "Cluster 80: Oligodendrocytes - Myelination" 48 "CAB070425: " "unprognostic (1.22e-1)" "unprognostic (2.68e-3)" "unprognostic (2.66e-1)" "unprognostic (2.52e-1)" "unprognostic (1.42e-1)" "unprognostic (8.76e-2)" "unprognostic (9.46e-2)" "unprognostic (2.19e-3)" "unprognostic (2.52e-1)" "unprognostic (1.98e-1)" "unprognostic (4.12e-1)" "unprognostic (4.11e-2)" "potential prognostic favorable (5.81e-5)" "potential prognostic unfavorable (6.82e-8)" "unprognostic (1.36e-1)" "unprognostic (2.50e-2)" "unprognostic (3.12e-1)" "unprognostic (3.17e-1)" "unprognostic (6.55e-3)" "unprognostic (2.27e-1)" "unprognostic (6.56e-2)" "potential prognostic favorable (1.61e-4)" "unprognostic (5.03e-2)" "unprognostic (2.12e-1)" "unprognostic (1.85e-1)" "unprognostic (2.35e-2)" "unprognostic (5.19e-2)" "unprognostic (3.48e-1)" "unprognostic (4.31e-2)" "unprognostic (3.25e-2)" "unprognostic (1.90e-1)" IPO4 "FLJ23338, Imp4" ENSG00000196497 "Importin 4" Q8TEX9 14 24180219-24188869 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 55.2" "Cell type enhanced" "Detected in some" "Astrocytes: 2.3;Bergmann glia: 2.0;Brain excitatory neurons: 1.5;Brain inhibitory neurons: 1.5;Choroid plexus epithelial cells: 1.8;Distal convoluted tubule cells: 1.1;Ependymal cells: 3.2;Loop of henle epithelial cells: 1.2;Oligodendrocyte progenitor cells: 1.6;Oligodendrocytes: 1.8;Other brain neurons: 1.7;Proximal tubule cells: 1.5;Renal collecting duct principal cells: 1.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Kidney - Macrophages, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039043, HPA064572" Uncertain Approved Cytosol NA NA 38000 "Cluster 30: Non-specific - DNA binding" "Cluster 21: Testis - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 98: Neurons - Neurotransmission & signaling" 47 Cytosol "HPA039043: , HPA064572: " "unprognostic (1.25e-3)" "unprognostic (1.63e-1)" "unprognostic (1.25e-1)" "unprognostic (1.54e-1)" "unprognostic (2.58e-2)" "unprognostic (2.43e-1)" "unprognostic (3.14e-1)" "unprognostic (1.21e-3)" "unprognostic (1.19e-2)" "unprognostic (2.15e-1)" "unprognostic (4.11e-2)" "unprognostic (2.26e-1)" "unprognostic (1.15e-1)" "validated prognostic unfavorable (4.46e-7)" "validated prognostic unfavorable (1.60e-4)" "unprognostic (7.39e-3)" "unprognostic (7.95e-3)" "unprognostic (3.03e-1)" "unprognostic (2.36e-1)" "unprognostic (3.30e-2)" "unprognostic (9.47e-2)" "unprognostic (8.50e-2)" "unprognostic (1.93e-1)" "unprognostic (5.70e-2)" "unprognostic (1.39e-1)" "unprognostic (1.99e-1)" "unprognostic (3.95e-2)" "unprognostic (2.98e-1)" "unprognostic (2.02e-1)" "unprognostic (3.60e-2)" "unprognostic (3.63e-1)" IPO5 "IMB3, KPNB3, MGC2068, PSE1, RANBP5" ENSG00000065150 "Importin 5" O00410 13 97953658-98024296 "Plasma proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 196.2" "Cell type enhanced" "Detected in all" "Early spermatids: 1447.9;Late primary spermatocytes: 586.0;Late spermatids: 3125.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009110, HPA040983, HPA056548" Approved Supported "Nucleoplasm,Nuclear membrane,Golgi apparatus,Cytosol" NA NA 770000 "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 53: Neurons - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 114 "Nucleoplasm, Nuclear membrane" "Golgi apparatus, Cytosol" "CAB009110: , HPA040983: , HPA056548: " "unprognostic (1.30e-1)" "unprognostic (1.36e-1)" "unprognostic (7.87e-2)" "unprognostic (4.95e-2)" "unprognostic (1.63e-1)" "unprognostic (2.63e-2)" "unprognostic (4.56e-2)" "unprognostic (2.79e-1)" "unprognostic (7.57e-2)" "unprognostic (4.04e-2)" "potential prognostic favorable (2.45e-9)" "unprognostic (1.86e-3)" "unprognostic (2.39e-1)" "unprognostic (2.11e-2)" "potential prognostic unfavorable (4.06e-6)" "unprognostic (8.19e-2)" "unprognostic (2.14e-3)" "unprognostic (7.91e-3)" "unprognostic (2.55e-1)" "unprognostic (1.90e-1)" "unprognostic (5.36e-2)" "unprognostic (4.94e-2)" "unprognostic (4.46e-2)" "unprognostic (9.71e-2)" "unprognostic (2.16e-3)" "unprognostic (5.63e-2)" "unprognostic (1.14e-1)" "unprognostic (2.75e-1)" "unprognostic (1.34e-1)" "unprognostic (9.91e-2)" "unprognostic (1.39e-1)" IPO7 "Imp7, RANBP7" ENSG00000205339 "Importin 7" O95373 11 9384652-9448127 "Cancer-related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019002, HPA056590" Approved Approved Supported Nucleoplasm,Cytosol NA NA 290000 "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 80 "Nucleoplasm, Cytosol" "HPA019002: , HPA056590: " "unprognostic (2.99e-2)" "unprognostic (7.37e-2)" "unprognostic (8.63e-2)" "unprognostic (2.89e-3)" "unprognostic (2.62e-1)" "unprognostic (6.12e-2)" "unprognostic (1.93e-1)" "unprognostic (2.13e-2)" "unprognostic (1.91e-2)" "unprognostic (1.45e-2)" "potential prognostic favorable (7.21e-5)" "unprognostic (6.38e-2)" "potential prognostic unfavorable (7.97e-4)" "potential prognostic unfavorable (1.21e-4)" "unprognostic (1.29e-3)" "unprognostic (1.94e-2)" "unprognostic (9.91e-3)" "unprognostic (9.40e-2)" "unprognostic (6.32e-2)" "unprognostic (1.87e-1)" "unprognostic (1.38e-2)" "potential prognostic unfavorable (3.16e-6)" "unprognostic (1.97e-2)" "unprognostic (8.22e-2)" "unprognostic (1.12e-2)" "unprognostic (2.65e-1)" "unprognostic (1.35e-1)" "unprognostic (9.16e-2)" "unprognostic (6.67e-2)" "unprognostic (1.10e-1)" "unprognostic (1.26e-2)" IPO8 "IMP8, RANBP8" ENSG00000133704 "Importin 8" O15397 12 30628988-30695869 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Aortic aneurysm, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018439, HPA023765" Uncertain Approved "Nucleoplasm,Vesicles,End piece" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 55: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 77 Nucleoplasm "Vesicles, End piece" "HPA018439: , HPA023765: " "unprognostic (3.68e-1)" "unprognostic (2.50e-2)" "unprognostic (2.24e-1)" "unprognostic (2.78e-2)" "unprognostic (2.23e-1)" "unprognostic (1.00e-1)" "unprognostic (8.85e-2)" "unprognostic (2.46e-1)" "unprognostic (1.04e-1)" "potential prognostic unfavorable (3.23e-4)" "potential prognostic favorable (1.89e-5)" "unprognostic (1.54e-3)" "unprognostic (4.12e-2)" "unprognostic (1.04e-2)" "unprognostic (2.08e-2)" "unprognostic (2.66e-2)" "unprognostic (1.97e-3)" "unprognostic (1.34e-1)" "unprognostic (1.76e-1)" "unprognostic (3.23e-2)" "unprognostic (5.52e-2)" "unprognostic (9.47e-2)" "unprognostic (1.13e-1)" "unprognostic (7.72e-2)" "unprognostic (6.79e-2)" "unprognostic (8.42e-2)" "unprognostic (1.88e-2)" "unprognostic (3.73e-1)" "unprognostic (4.29e-1)" "unprognostic (1.99e-2)" "unprognostic (1.63e-1)" IPO9 "FLJ10402, Imp9" ENSG00000198700 "Importin 9" Q96P70 1 201829149-201884291 "Essential proteins, Predicted intracellular proteins, Transporters" "Protein transport, Transport" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018249, HPA020866" Supported Nucleoplasm,Cytosol NA NA 130000 "Cluster 25: Non-specific - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 44 Cytosol Nucleoplasm "HPA018249: , HPA020866: " "unprognostic (8.78e-2)" "unprognostic (1.84e-1)" "unprognostic (2.12e-1)" "unprognostic (1.05e-3)" "unprognostic (1.85e-1)" "unprognostic (1.00e-1)" "unprognostic (2.61e-1)" "unprognostic (8.97e-2)" "unprognostic (1.73e-1)" "unprognostic (7.20e-2)" "unprognostic (2.56e-2)" "unprognostic (4.10e-1)" "unprognostic (1.27e-3)" "potential prognostic unfavorable (1.21e-5)" "unprognostic (1.16e-2)" "unprognostic (4.36e-3)" "unprognostic (1.69e-2)" "unprognostic (1.97e-2)" "unprognostic (2.27e-1)" "unprognostic (1.72e-1)" "unprognostic (3.15e-1)" "unprognostic (1.69e-1)" "unprognostic (1.47e-3)" "unprognostic (1.86e-1)" "unprognostic (2.54e-1)" "unprognostic (8.88e-2)" "unprognostic (3.41e-2)" "unprognostic (2.79e-1)" "unprognostic (1.10e-1)" "unprognostic (3.72e-1)" "unprognostic (9.82e-3)" IPP KLHL27 ENSG00000197429 "Intracisternal A particle-promoted polypeptide" Q9Y573 1 45694324-45750653 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075545 Approved NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 105: Non-specific - Mixed function" 2 "HPA075545: " "unprognostic (2.56e-1)" "unprognostic (1.15e-2)" "unprognostic (1.73e-1)" "unprognostic (6.70e-2)" "unprognostic (2.41e-2)" "unprognostic (2.59e-1)" "unprognostic (3.47e-1)" "unprognostic (7.09e-3)" "unprognostic (2.83e-2)" "unprognostic (9.80e-2)" "validated prognostic favorable (2.47e-7)" "validated prognostic favorable (5.64e-4)" "unprognostic (1.23e-1)" "potential prognostic unfavorable (1.10e-4)" "unprognostic (6.43e-2)" "unprognostic (1.60e-1)" "unprognostic (9.00e-2)" "unprognostic (6.30e-2)" "unprognostic (1.86e-1)" "unprognostic (1.87e-1)" "unprognostic (7.92e-2)" "unprognostic (3.88e-2)" "unprognostic (1.23e-1)" "unprognostic (1.87e-1)" "unprognostic (2.85e-3)" "unprognostic (9.26e-2)" "unprognostic (5.04e-2)" "unprognostic (5.22e-2)" "unprognostic (2.03e-1)" "unprognostic (1.43e-2)" "unprognostic (2.48e-1)" IPPK "C9orf12, FLJ13163, INSP5K2, IP5K, IPK1" ENSG00000127080 "Inositol-pentakisphosphate 2-kinase" Q9H8X2 9 92613183-92670131 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 30.7" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 207.9;Esophageal basal cells: 89.6;Esophageal suprabasal cells: 163.0;Suprabasal keratinocytes: 139.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020603 Uncertain Approved Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 37: Neurons - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 85: Squamous epithelial cells - Keratinization" Cytosol "HPA020603: " "unprognostic (2.79e-1)" "unprognostic (1.18e-2)" "unprognostic (1.14e-1)" "unprognostic (9.95e-2)" "unprognostic (3.47e-2)" "unprognostic (1.28e-1)" "unprognostic (5.53e-1)" "potential prognostic favorable (7.67e-5)" "unprognostic (3.19e-1)" "unprognostic (4.74e-1)" "potential prognostic favorable (5.24e-6)" "unprognostic (1.51e-3)" "unprognostic (9.31e-3)" "unprognostic (2.38e-2)" "unprognostic (2.72e-1)" "potential prognostic unfavorable (9.53e-4)" "unprognostic (4.34e-2)" "unprognostic (2.05e-1)" "unprognostic (4.06e-2)" "unprognostic (1.77e-1)" "unprognostic (8.62e-2)" "unprognostic (4.36e-2)" "unprognostic (1.84e-1)" "unprognostic (8.85e-2)" "unprognostic (2.18e-2)" "unprognostic (6.70e-2)" "unprognostic (3.27e-1)" "unprognostic (1.96e-2)" "unprognostic (4.15e-2)" "unprognostic (2.03e-1)" "unprognostic (2.21e-1)" IQANK1 "FAM83H-AS1, onco-lncRNA-3" ENSG00000203499 "IQ motif and ankyrin repeat containing 1" A8MXQ7 8 143734139-143790645 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 39.7;skin 1: 27.0" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 7.2;Choroid plexus epithelial cells: 17.5;Distal convoluted tubule cells: 12.9;Ependymal cells: 59.8;Late primary spermatocytes: 7.5;Loop of henle epithelial cells: 17.2;Papillary tip epithelial cells: 39.9;Proximal tubule cells: 10.0;Renal collecting duct intercalated cells: 10.3;Renal collecting duct principal cells: 34.5;Renal connecting tubule cells: 17.7" "Cell type enhanced" "Detected in many" "ependymal cell: 69.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 58: Skin - Keratinization" "Cluster 17: Choroid plexus - Cilium" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 34: Ciliated cells - Cilia assembly & function" "unprognostic (2.18e-3)" "unprognostic (1.40e-3)" "unprognostic (7.13e-2)" "unprognostic (1.49e-1)" "unprognostic (1.93e-1)" "unprognostic (2.58e-1)" "unprognostic (2.49e-1)" "unprognostic (4.07e-3)" "unprognostic (3.05e-1)" "unprognostic (5.26e-3)" "unprognostic (3.13e-3)" "unprognostic (9.80e-2)" "unprognostic (8.70e-2)" "unprognostic (2.70e-3)" "unprognostic (2.00e-2)" "unprognostic (3.05e-1)" "unprognostic (3.72e-3)" "unprognostic (3.87e-2)" "unprognostic (2.83e-1)" "unprognostic (4.22e-2)" "unprognostic (3.17e-1)" "unprognostic (1.08e-1)" "unprognostic (6.80e-3)" "unprognostic (7.38e-2)" "unprognostic (7.31e-2)" "unprognostic (2.39e-1)" IQCA1 "DRC11, FLJ22527, IQCA" ENSG00000132321 "IQ motif containing with AAA domain 1" Q86XH1 2 236324147-236507535 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.7;choroid plexus: 47.4;thyroid gland: 18.0" "Cell type enhanced" "Detected in many" "Astrocytes: 369.9;Choroid plexus epithelial cells: 190.1;Ependymal cells: 413.2;Fallopian tube ciliated cells: 159.4;Pituitary stem cells: 159.4;Respiratory ciliated cells: 282.3" "Cell type enhanced" "Detected in all" "astrocyte: 457.2;ependymal cell: 412.7" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 23.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD8 T-cell: 1.4" "Lineage enhanced" "Detected in single" "T-cells: 1.4" "Cancer enhanced" "Detected in some" "testis cancer: 4.1" "Adipose visceral - Mesothelial cells, Lung - Respiratory ciliated cells, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA031547 Approved "Vesicles,Primary cilium,Primary cilium tip,Flagellar centriole" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 28: Astrocytes - Homeostasis & neuron support" "Flagellar centriole" "Vesicles, Primary cilium, Primary cilium tip" "HPA031547: " "unprognostic (4.80e-2)" "unprognostic (1.20e-1)" "unprognostic (1.57e-1)" "unprognostic (1.09e-1)" "potential prognostic unfavorable (3.10e-4)" "unprognostic (7.64e-2)" "unprognostic (2.60e-2)" "unprognostic (4.24e-3)" "unprognostic (6.09e-2)" "unprognostic (1.32e-3)" "unprognostic (8.04e-2)" "unprognostic (2.39e-2)" "unprognostic (2.77e-1)" "unprognostic (1.86e-1)" "unprognostic (9.12e-2)" "unprognostic (2.66e-2)" "unprognostic (4.56e-2)" "unprognostic (1.24e-1)" "unprognostic (8.47e-3)" "unprognostic (2.62e-2)" "unprognostic (2.45e-2)" IQCA1L "IQCA1P1, TCAG_9762" ENSG00000278685 "IQ motif containing with AAA domain 1 like" A6NCM1 7 151190873-151205496 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 22 "testis: 4.1" "Group enriched" "Detected in some" 22 "Early spermatids: 30.5;Late primary spermatocytes: 49.9;Late spermatids: 38.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" IQCB1 "KIAA0036, NPHP5, SLSN5" ENSG00000173226 "IQ motif containing B1" Q15051 3 121769761-121835079 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" Calmodulin-binding "Ciliopathy, Leber congenital amaurosis, Nephronophthisis, Senior-Loken syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early primary spermatocytes: 274.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042028 Approved Approved Uncertain "Nucleoplasm,Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Basal body" Yes NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 39: Testis - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 27 "Microtubules, Cytokinetic bridge, Mitotic spindle" "Nucleoplasm, Primary cilium, Basal body" "HPA042028: " "unprognostic (1.35e-2)" "unprognostic (1.70e-1)" "unprognostic (1.13e-1)" "unprognostic (4.78e-3)" "unprognostic (2.76e-1)" "unprognostic (3.92e-1)" "unprognostic (1.15e-1)" "unprognostic (3.22e-1)" "unprognostic (1.58e-2)" "unprognostic (1.09e-1)" "unprognostic (4.20e-3)" "unprognostic (1.74e-1)" "unprognostic (4.27e-2)" "potential prognostic unfavorable (3.74e-5)" "unprognostic (1.53e-2)" "unprognostic (2.22e-3)" "unprognostic (6.62e-2)" "unprognostic (6.29e-2)" "unprognostic (4.78e-2)" "unprognostic (2.98e-1)" "unprognostic (4.73e-1)" "unprognostic (2.63e-1)" "unprognostic (3.88e-2)" "unprognostic (3.91e-3)" "validated prognostic favorable (1.15e-4)" "validated prognostic favorable (2.35e-4)" "unprognostic (1.62e-1)" "unprognostic (1.57e-2)" "unprognostic (5.13e-1)" "unprognostic (5.38e-2)" "unprognostic (7.11e-2)" IQCC FLJ10547 ENSG00000160051 "IQ motif containing C" Q4KMZ1 1 32205671-32208682 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 8.6" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 10.6;Breast lactating cells: 17.6;Early primary spermatocytes: 22.3;Epicardial cells: 22.7;Fallopian tube ciliated cells: 10.9;Late primary spermatocytes: 13.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028602, HPA028686" Approved Approved Vesicles NA NA "Cluster 24: Non-specific - Transcription" "Cluster 21: Testis - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 4 Vesicles "HPA028602: , HPA028686: " "unprognostic (3.14e-1)" "unprognostic (4.17e-2)" "unprognostic (2.13e-1)" "unprognostic (1.37e-1)" "unprognostic (2.24e-1)" "unprognostic (1.97e-1)" "unprognostic (5.73e-2)" "unprognostic (1.72e-2)" "unprognostic (1.13e-2)" "unprognostic (5.75e-2)" "unprognostic (2.92e-1)" "unprognostic (2.23e-3)" "unprognostic (3.30e-3)" "potential prognostic unfavorable (1.61e-5)" "unprognostic (1.06e-1)" "unprognostic (1.75e-3)" "unprognostic (1.39e-1)" "unprognostic (7.79e-2)" "unprognostic (1.67e-1)" "unprognostic (1.68e-1)" "unprognostic (3.13e-3)" "unprognostic (9.68e-3)" "unprognostic (2.83e-1)" "unprognostic (3.46e-1)" "unprognostic (4.21e-2)" "unprognostic (4.25e-2)" "unprognostic (3.76e-2)" "unprognostic (1.29e-2)" "potential prognostic favorable (4.08e-4)" "unprognostic (2.99e-2)" "unprognostic (9.19e-2)" IQCD "CFAP84, DRC10" ENSG00000166578 "IQ motif containing D" Q96DY2 12 113195441-113221094 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "choroid plexus: 20.8;fallopian tube: 20.7;testis: 42.0" "Cell type enhanced" "Detected in many" "Early spermatids: 140.2;Endometrial ciliated cells: 94.5;Ependymal cells: 62.9;Epididymal efferent duct ciliated cells: 102.8;Esophageal apical cells: 88.5;Fallopian tube ciliated cells: 172.3;Late primary spermatocytes: 240.9;Late spermatids: 134.6;Respiratory ciliated cells: 179.1" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 30.5;ependymal cell: 71.4" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 15.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 1.9;plasmacytoid DC: 1.4" "Group enriched" "Detected in many" 5 "dendritic cells: 1.4;granulocytes: 1.9;monocytes: 1.1" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Spleen - Fibroblasts_1, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA046810 Supported Approved "Mid piece,Principal piece,End piece" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 107: Ciliated cells - Cilia assembly & function" "Mid piece, Principal piece, End piece" "HPA046810: " "unprognostic (2.42e-1)" "unprognostic (2.69e-1)" "unprognostic (1.25e-1)" "unprognostic (5.87e-2)" "unprognostic (2.26e-2)" "unprognostic (8.28e-2)" "unprognostic (1.19e-1)" "unprognostic (1.58e-1)" "unprognostic (2.11e-3)" "unprognostic (7.82e-3)" "unprognostic (1.78e-1)" "unprognostic (5.24e-2)" "potential prognostic unfavorable (6.76e-6)" "unprognostic (1.61e-2)" "unprognostic (4.44e-3)" "unprognostic (6.82e-2)" "unprognostic (7.45e-2)" "unprognostic (2.41e-1)" "unprognostic (1.09e-1)" "potential prognostic favorable (6.95e-4)" "unprognostic (2.53e-2)" "unprognostic (1.61e-1)" "unprognostic (1.01e-1)" "unprognostic (2.11e-1)" "unprognostic (2.74e-1)" "unprognostic (1.16e-1)" "unprognostic (2.99e-2)" "unprognostic (8.13e-2)" "unprognostic (5.02e-2)" IQCE KIAA1023 ENSG00000106012 "IQ motif containing E" Q6IPM2 7 2558972-2614733 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 561.7;Late primary spermatocytes: 185.1;Late spermatids: 557.6;Respiratory ciliated cells: 137.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 3.8" "Group enriched" "Detected in many" 4 "dendritic cells: 2.4;granulocytes: 3.8;monocytes: 1.2" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" HPA019515 Approved Approved "Nucleoplasm,Nuclear membrane,Plasma membrane,Primary cilium" Yes No "Cluster 21: Neutrophils - Unknown function" "Cluster 21: Testis - Mixed function" "Cluster 17: Choroid plexus - Cilium" "Cluster 67: Non-specific - Unknown function" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 9 "Nucleoplasm, Plasma membrane" "Nuclear membrane, Primary cilium" "HPA019515: " "unprognostic (1.77e-1)" "unprognostic (4.05e-1)" "unprognostic (4.67e-1)" "unprognostic (8.65e-3)" "unprognostic (1.07e-1)" "unprognostic (3.01e-1)" "unprognostic (7.67e-2)" "unprognostic (5.90e-2)" "unprognostic (1.94e-1)" "unprognostic (6.50e-3)" "unprognostic (1.51e-1)" "unprognostic (2.49e-1)" "unprognostic (5.41e-3)" "potential prognostic unfavorable (1.69e-4)" "unprognostic (5.19e-2)" "unprognostic (1.20e-2)" "unprognostic (2.49e-2)" "unprognostic (3.37e-1)" "unprognostic (3.69e-1)" "unprognostic (2.16e-2)" "unprognostic (2.16e-1)" "unprognostic (2.63e-2)" "unprognostic (2.35e-2)" "unprognostic (8.56e-2)" "unprognostic (6.75e-2)" "unprognostic (2.55e-1)" "unprognostic (2.02e-2)" "unprognostic (1.47e-2)" "unprognostic (4.56e-2)" "unprognostic (3.20e-2)" "unprognostic (2.43e-1)" IQCF1 MGC39725 ENSG00000173389 "IQ motif containing F1" Q8N6M8 3 51894876-51903353 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 651 "testis: 65.1" "Group enriched" "Detected in some" 14 "Early spermatids: 1505.8;Late spermatids: 4488.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 15: Kidney cancer - Membrane components" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" IQCF2 ENSG00000184345 "IQ motif containing F2" Q8IXL9 3 51861615-51863424 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 155 "testis: 15.5" "Group enriched" "Detected in some" 22 "Early spermatids: 1321.6;Late spermatids: 3515.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Low region specificity" "Detected in some" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 14 IQCF3 ENSG00000229972 "IQ motif containing F3" P0C7M6 3 51826883-51833389 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 258 "testis: 101.9" "Group enriched" "Detected in some" 4 "Early spermatids: 139.3;Late spermatids: 119.9" "Cell type enriched" "Detected in single" 6 "deep-layer corticothalamic and 6b: 2.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA055755 Approved Nucleoli NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 34: Non-specific - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 1 Nucleoli "HPA055755: " IQCF5 ENSG00000214681 "IQ motif containing F5" A8MTL0 3 51873721-51875601 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 956 "testis: 95.6" "Group enriched" "Detected in some" 5 "Early spermatids: 958.5;Late spermatids: 3724.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" IQCF6 ENSG00000214686 "IQ motif containing F6" A8MYZ5 3 51778561-51779241 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 69 "testis: 23.8" "Group enriched" "Detected in some" 17 "Early spermatids: 516.8;Late spermatids: 227.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" IQCG "CFAP122, DKFZp434B227, DRC9" ENSG00000114473 "IQ motif containing G" Q9H095 3 197889077-197960142 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 51.6;fallopian tube: 49.6;testis: 41.0" "Cell type enhanced" "Detected in many" "Early spermatids: 300.1;Endometrial ciliated cells: 300.1;Ependymal cells: 327.4;Epididymal efferent duct ciliated cells: 327.8;Fallopian tube ciliated cells: 352.3;Granulosa cells: 454.2;Late primary spermatocytes: 255.2;Late spermatids: 666.1;Mesothelial cells: 236.0;Respiratory ciliated cells: 426.4" "Cell type enhanced" "Detected in all" "ependymal cell: 356.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042787, HPA051981" Enhanced Approved "Actin filaments,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 94: Gonadal somatic cells - Mixed function" "Actin filaments, Cytosol" "HPA042787: , HPA051981: " "unprognostic (3.16e-2)" "unprognostic (1.10e-1)" "unprognostic (1.78e-3)" "unprognostic (1.40e-3)" "unprognostic (1.45e-1)" "unprognostic (2.19e-1)" "unprognostic (1.03e-2)" "potential prognostic unfavorable (3.10e-4)" "unprognostic (3.07e-1)" "unprognostic (6.84e-2)" "unprognostic (1.36e-3)" "unprognostic (6.57e-2)" "unprognostic (6.82e-2)" "unprognostic (2.43e-2)" "unprognostic (8.91e-2)" "unprognostic (3.17e-1)" "unprognostic (9.72e-2)" "unprognostic (1.49e-1)" "unprognostic (2.25e-2)" "unprognostic (1.76e-1)" "unprognostic (2.41e-2)" "unprognostic (4.57e-2)" "unprognostic (7.29e-2)" "unprognostic (1.47e-1)" "unprognostic (6.47e-2)" "unprognostic (1.94e-3)" "unprognostic (2.29e-1)" "unprognostic (1.09e-1)" "unprognostic (3.83e-1)" "unprognostic (7.34e-3)" "unprognostic (1.02e-1)" IQCH FLJ12476 ENSG00000103599 "IQ motif containing H" Q86VS3 15 67254786-67502260 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 6.4;testis: 10.8" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 169.0;Early primary spermatocytes: 222.6;Endometrial ciliated cells: 189.5;Ependymal cells: 446.6;Fallopian tube ciliated cells: 191.5;Myonuclei: 169.5;Respiratory ciliated cells: 467.5" "Group enriched" "Detected in all" 4 "choroid plexus epithelial cell: 134.5;ependymal cell: 475.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA040845 Uncertain Approved "Vesicles,Cytosol,Mid piece" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" Cytosol "Vesicles, Mid piece" "HPA040845: " "unprognostic (1.60e-1)" "unprognostic (1.17e-1)" "unprognostic (1.28e-1)" "unprognostic (6.54e-3)" "unprognostic (2.09e-1)" "unprognostic (3.16e-2)" "unprognostic (4.40e-1)" "unprognostic (9.98e-3)" "potential prognostic favorable (6.75e-5)" "unprognostic (1.75e-3)" "potential prognostic favorable (4.46e-4)" "unprognostic (3.38e-2)" "unprognostic (9.50e-2)" "unprognostic (7.02e-2)" "unprognostic (1.97e-1)" "unprognostic (2.12e-1)" "unprognostic (5.08e-1)" "unprognostic (1.99e-1)" "unprognostic (3.23e-2)" "unprognostic (1.80e-1)" "unprognostic (1.12e-2)" "unprognostic (1.74e-1)" "unprognostic (1.43e-1)" "unprognostic (1.72e-2)" "unprognostic (3.74e-2)" IQCJ ENSG00000214216 "IQ motif containing J" Q1A5X6 3 158962928-159266307 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Astrocytes: 36.0;Bergmann glia: 17.3;Brain excitatory neurons: 133.7;Brain inhibitory neurons: 114.2;Early spermatids: 19.0;Late spermatids: 40.3;Oligodendrocyte progenitor cells: 15.0;Oligodendrocytes: 27.9;Other brain neurons: 60.3" "Cell type enhanced" "Detected in all" "hippocampal CA4: 470.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA052835 Uncertain NA NA "Cluster 51: Neurons - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" "HPA052835: " IQCJ-SCHIP1 ENSG00000283154 "IQCJ-SCHIP1 readthrough" B3KU38 3 158962235-159897629 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 90.7" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 623.1;Pituitary stem cells: 9936.4;Podocytes: 2998.9;Retinal bipolar cells: 1870.4" "Cancer enhanced" "Detected in all" "Kidney Renal Papillary Cell Carcinoma (TCGA): 74.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Spleen - Fibroblasts_1, Testis - Spermatogonia" "HPA003243, HPA003445" Approved Approved Cytosol NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 15: Kidney cancer - Membrane components" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" Cytosol "HPA003243: , HPA003445: " "unprognostic (2.18e-1)" "unprognostic (2.18e-1)" "unprognostic (7.50e-2)" "unprognostic (2.66e-2)" "unprognostic (5.10e-2)" "unprognostic (1.40e-1)" "unprognostic (1.68e-3)" "unprognostic (1.89e-1)" "unprognostic (9.04e-2)" "unprognostic (1.12e-2)" "unprognostic (1.59e-2)" "unprognostic (1.38e-2)" "unprognostic (2.15e-2)" "potential prognostic unfavorable (6.99e-4)" "unprognostic (6.85e-2)" "unprognostic (2.22e-1)" "unprognostic (1.81e-1)" "unprognostic (1.08e-1)" "unprognostic (6.89e-2)" "unprognostic (8.59e-2)" "unprognostic (8.26e-3)" "unprognostic (2.14e-2)" "unprognostic (1.21e-2)" "unprognostic (3.60e-1)" "unprognostic (1.15e-2)" "unprognostic (7.99e-3)" IQCK "FLJ36575, MGC35048" ENSG00000174628 "IQ motif containing K" Q8N0W5 16 19716456-19858467 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 227.3;Bergmann glia: 230.0;Cone photoreceptor cells: 227.7;Ependymal cells: 353.7;Fallopian tube ciliated cells: 230.7;Respiratory ciliated cells: 333.1;Rod photoreceptor cells: 339.8" "Cell type enhanced" "Detected in all" "ependymal cell: 389.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Spleen - Endothelial cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026792, HPA048786" Approved Approved "Nuclear speckles,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 28: Astrocytes - Homeostasis & neuron support" "Nuclear speckles" Cytosol "HPA026792: , HPA048786: " "unprognostic (3.14e-3)" "unprognostic (2.74e-2)" "unprognostic (1.59e-2)" "unprognostic (8.62e-2)" "unprognostic (1.51e-1)" "unprognostic (1.79e-1)" "unprognostic (9.63e-2)" "unprognostic (2.28e-3)" "unprognostic (1.22e-1)" "unprognostic (1.11e-1)" "potential prognostic favorable (1.30e-7)" "unprognostic (7.23e-3)" "unprognostic (4.36e-2)" "unprognostic (8.01e-2)" "unprognostic (9.35e-3)" "unprognostic (5.74e-2)" "unprognostic (2.93e-1)" "unprognostic (1.10e-1)" "unprognostic (2.17e-1)" "unprognostic (1.59e-1)" "unprognostic (1.96e-2)" "unprognostic (1.58e-1)" "unprognostic (1.08e-1)" "unprognostic (5.21e-2)" "unprognostic (2.79e-2)" "unprognostic (1.70e-2)" "unprognostic (2.11e-2)" "unprognostic (1.11e-1)" "unprognostic (1.08e-1)" "unprognostic (2.16e-1)" "unprognostic (8.22e-2)" IQCM ENSG00000234828 "IQ motif containing M" A0A1B0GVH7 4 149351709-149896233 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 12 "testis: 4.3" "Cell type enhanced" "Detected in some" "Colonocytes: 80.2;Early spermatids: 180.4;Enteric stem cells: 29.7;Enteric transient amplifying cells: 44.0;Goblet cells: 93.4;Late primary spermatocytes: 231.1;Late spermatids: 26.9;Tuft cells: 92.2" "Cell type enhanced" "Detected in many" "ependymal cell: 12.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" IQCN KIAA1683 ENSG00000130518 "IQ motif containing N" Q9H0B3 19 18257098-18274500 "Human disease related genes, Predicted intracellular proteins" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "testis: 30.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 113.7;Early spermatids: 122.1;Late spermatids: 141.7;Medullary thymic epithelial cells: 127.2;Transitional alveolar cells: 115.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.6" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in some" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA042409 Enhanced Approved "Acrosome,Equatorial segment" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 15: Non-specific - Transcription" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 20: Non-specific - Transcription regulation" 10 "Acrosome, Equatorial segment" "HPA042409: " "unprognostic (8.42e-3)" "unprognostic (5.98e-2)" "unprognostic (1.44e-2)" "unprognostic (1.73e-1)" "unprognostic (7.09e-3)" "unprognostic (2.95e-2)" "unprognostic (2.52e-3)" "unprognostic (6.88e-2)" "unprognostic (4.58e-2)" "unprognostic (4.72e-1)" "unprognostic (1.52e-1)" "unprognostic (9.60e-2)" "potential prognostic favorable (5.92e-4)" "unprognostic (9.88e-3)" "unprognostic (2.09e-1)" "unprognostic (1.24e-2)" "unprognostic (1.56e-1)" "unprognostic (3.85e-2)" "unprognostic (8.47e-2)" "unprognostic (2.37e-1)" "unprognostic (1.25e-1)" IQGAP1 "HUMORFA01, KIAA0051, p195, SAR1" ENSG00000140575 "IQ motif containing GTPase activating protein 1" P46940 15 90388242-90502239 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 3203.3" "Cell type enhanced" "Detected in all" "oligodendrocyte: 555.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013302, HPA014055" Enhanced Supported "Plasma membrane,Cell Junctions" NA NA 1900000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 13: Lung - Secretion" "Cluster 11: White matter - Signal transduction" "Cluster 58: Non-specific - Nuclear processes" "Cluster 24: Neutrophils - Innate immunity signal integration" 116 "Plasma membrane, Cell Junctions" "CAB013302: , HPA014055: " "unprognostic (1.02e-1)" "unprognostic (3.37e-1)" "potential prognostic favorable (6.28e-5)" "unprognostic (7.95e-3)" "unprognostic (1.17e-1)" "unprognostic (2.26e-1)" "unprognostic (6.83e-2)" "unprognostic (2.73e-3)" "unprognostic (1.50e-1)" "unprognostic (2.12e-3)" "potential prognostic favorable (3.08e-7)" "unprognostic (2.16e-2)" "unprognostic (5.52e-2)" "unprognostic (7.88e-2)" "unprognostic (3.19e-1)" "unprognostic (3.42e-1)" "unprognostic (1.30e-2)" "unprognostic (1.28e-1)" "unprognostic (2.10e-2)" "unprognostic (4.01e-3)" "unprognostic (7.80e-2)" "potential prognostic unfavorable (1.08e-5)" "unprognostic (1.79e-2)" "unprognostic (1.36e-1)" "unprognostic (3.62e-3)" "unprognostic (1.39e-1)" "unprognostic (2.02e-1)" "unprognostic (1.52e-1)" "unprognostic (6.88e-2)" "unprognostic (1.76e-1)" "unprognostic (1.91e-1)" IQGAP2 ENSG00000145703 "IQ motif containing GTPase activating protein 2" Q13576 5 76403285-76708132 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 105.8" "Cell type enhanced" "Detected in many" "Early spermatids: 1327.8;Hematopoietic stem cells: 1342.6;Neutrophil progenitors: 821.6;Neutrophils: 1152.9;NK-cells: 960.4;Podocytes: 1896.0;Salivary ionocytes: 816.4;Thymocytes: 1528.7" "Group enriched" "Detected in many" 4 "ependymal cell: 335.0;fibroblast: 321.8;leukocyte: 868.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 21.3" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Liver - Hepatocytes, Pituitary gland - Undifferentiated cells (Pituitary gland), Prostate - Prostate glandular cells, Skeletal muscle - Macrophages, Skin - Eccrine sweat gland cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Region enhanced" "Detected in many" "hippocampal formation: 30.5" "Low region specificity" "Detected in all" "CAB004241, HPA037403, HPA037404" Uncertain Approved "Vesicles,Plasma membrane" NA NA 1700000 "Cluster 41: Basophils - Unknown function" "Cluster 21: Testis - Mixed function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 19 "Vesicles, Plasma membrane" "CAB004241: , HPA037403: , HPA037404: " "unprognostic (8.91e-2)" "unprognostic (2.42e-1)" "unprognostic (4.41e-1)" "unprognostic (8.45e-2)" "unprognostic (5.12e-2)" "unprognostic (1.31e-1)" "unprognostic (2.60e-2)" "unprognostic (1.05e-1)" "unprognostic (3.17e-2)" "potential prognostic unfavorable (8.85e-5)" "validated prognostic favorable (9.50e-12)" "validated prognostic favorable (9.89e-4)" "unprognostic (1.84e-2)" "unprognostic (1.08e-1)" "unprognostic (5.44e-3)" "unprognostic (1.68e-2)" "unprognostic (1.58e-1)" "unprognostic (2.57e-1)" "unprognostic (2.07e-1)" "unprognostic (3.21e-1)" "unprognostic (4.08e-2)" "unprognostic (1.23e-1)" "unprognostic (1.63e-2)" "unprognostic (2.00e-1)" "unprognostic (7.87e-2)" "unprognostic (1.29e-2)" "unprognostic (8.63e-2)" "unprognostic (7.52e-2)" "unprognostic (1.28e-1)" "unprognostic (7.79e-3)" "unprognostic (4.06e-2)" IQGAP3 ENSG00000183856 "IQ motif containing GTPase activating protein 3" Q86VI3 1 156525405-156572604 "Plasma proteins, Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.7" "Cell type enhanced" "Detected in some" "Early primary spermatocytes: 17.4;Enteric transient amplifying cells: 27.7;Erythrocyte progenitors: 11.3;Foveolar cells: 13.3;Gastric progenitor cells: 39.7;Late spermatids: 40.3;Monocyte progenitors: 39.2;Neutrophil progenitors: 14.7" "Cell type enhanced" "Detected in some" "deep-layer near-projecting: 2.7;lower rhombic lip: 1.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA030142, HPA030143" Uncertain Approved "Nucleoplasm,Nucleoli rim,Mitotic chromosome" Yes Yes "Cluster 44: Bone marrow - Nuclear processes" "Cluster 24: Neurons - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 27: Non-specific - Cell proliferation" 52 "Nucleoli rim" "Nucleoplasm, Mitotic chromosome" "HPA030142: , HPA030143: " "unprognostic (3.55e-1)" "unprognostic (9.29e-2)" "unprognostic (4.26e-1)" "unprognostic (4.52e-2)" "unprognostic (1.13e-1)" "unprognostic (2.53e-1)" "unprognostic (1.71e-1)" "unprognostic (1.48e-1)" "unprognostic (2.79e-2)" "validated prognostic unfavorable (3.88e-8)" "validated prognostic unfavorable (9.32e-7)" "potential prognostic unfavorable (1.74e-6)" "validated prognostic unfavorable (4.53e-5)" "validated prognostic unfavorable (4.57e-4)" "unprognostic (1.17e-3)" "potential prognostic unfavorable (1.18e-4)" "unprognostic (1.29e-1)" "unprognostic (1.50e-1)" "unprognostic (2.70e-1)" "unprognostic (3.04e-3)" "unprognostic (5.96e-3)" "unprognostic (4.88e-2)" "unprognostic (1.66e-2)" "unprognostic (3.26e-1)" "unprognostic (8.74e-2)" "unprognostic (7.04e-2)" "unprognostic (4.47e-2)" "unprognostic (3.58e-1)" "unprognostic (3.82e-2)" IQSEC1 "ARF-GEP100, BRAG2, GEP100, KIAA0763" ENSG00000144711 "IQ motif and Sec7 domain ArfGEF 1" Q6DN90 3 12897043-13283281 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 573.4;Neutrophils: 1218.1;Retinal ganglion cells: 397.9;Retinal horizontal cells: 631.1;Rod photoreceptor cells: 562.7;Sertoli cells: 371.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 28.6" "Lineage enriched" "Detected in all" 4 "granulocytes: 28.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038143, HPA038144, HPA069864" Uncertain Supported Nucleoplasm,Vesicles,Centrosome,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 55: Lymphoma - Immune response" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 24 Cytosol "Nucleoplasm, Vesicles, Centrosome" "HPA038143: , HPA038144: , HPA069864: " "unprognostic (1.63e-2)" "potential prognostic unfavorable (5.55e-4)" "unprognostic (6.10e-2)" "unprognostic (2.91e-1)" "unprognostic (1.39e-1)" "unprognostic (3.24e-1)" "unprognostic (3.89e-2)" "unprognostic (1.66e-2)" "unprognostic (2.40e-2)" "potential prognostic unfavorable (5.29e-4)" "potential prognostic favorable (8.82e-7)" "unprognostic (1.22e-3)" "unprognostic (3.09e-2)" "unprognostic (3.65e-2)" "unprognostic (1.10e-1)" "unprognostic (4.39e-2)" "unprognostic (2.29e-1)" "unprognostic (5.25e-2)" "unprognostic (4.54e-1)" "unprognostic (1.58e-2)" "unprognostic (1.72e-3)" "unprognostic (6.90e-3)" "unprognostic (4.83e-2)" "unprognostic (3.40e-1)" "unprognostic (7.30e-2)" "unprognostic (2.21e-3)" "unprognostic (4.08e-1)" "unprognostic (2.66e-1)" "unprognostic (6.63e-2)" "potential prognostic unfavorable (5.99e-4)" "unprognostic (2.05e-1)" IQSEC2 "BRAG1, IQ-ArfGEF, KIAA0522, MRX1, MRX18, MRX78" ENSG00000124313 "IQ motif and Sec7 domain ArfGEF 2" Q5JU85 X 53225828-53321350 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 57.4" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 83.8;Late spermatids: 111.7;Podocytes: 267.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 10.4;plasmacytoid DC: 10.6" "Group enriched" "Detected in many" 17 "dendritic cells: 10.6;monocytes: 10.4" "Low cancer specificity" "Detected in many" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003973, HPA076533" Approved "Vesicles,Lipid droplets" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 51: Neurons - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 57: Podocytes - Glomerular filtration" 6 "Vesicles, Lipid droplets" "HPA003973: , HPA076533: " "unprognostic (1.91e-1)" "unprognostic (3.49e-2)" "unprognostic (4.34e-1)" "unprognostic (1.79e-1)" "unprognostic (3.23e-1)" "unprognostic (3.81e-2)" "unprognostic (2.89e-3)" "unprognostic (1.63e-1)" "unprognostic (2.25e-1)" "unprognostic (5.08e-2)" "potential prognostic favorable (4.83e-4)" "unprognostic (7.36e-2)" "unprognostic (1.59e-1)" "unprognostic (2.83e-2)" "unprognostic (5.32e-2)" "unprognostic (6.71e-3)" "potential prognostic unfavorable (4.75e-4)" "unprognostic (2.77e-1)" "unprognostic (4.12e-2)" "unprognostic (8.73e-2)" "unprognostic (2.56e-1)" "unprognostic (1.57e-2)" "unprognostic (7.01e-2)" "unprognostic (4.10e-2)" "unprognostic (3.13e-1)" "unprognostic (9.00e-2)" "unprognostic (1.95e-1)" "unprognostic (5.39e-3)" "unprognostic (1.75e-1)" "unprognostic (1.25e-1)" "unprognostic (2.64e-1)" IQSEC3 "KIAA1110, MGC30156" ENSG00000120645 "IQ motif and Sec7 domain ArfGEF 3" Q9UPP2 12 66767-178455 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 60.6" "Group enriched" "Detected in many" 4 "Brain excitatory neurons: 108.8;Brain inhibitory neurons: 82.8;Early primary spermatocytes: 65.9;Other brain neurons: 119.5;Proximal tubule cells: 32.2;Retinal amacrine cells: 87.3;Retinal horizontal cells: 48.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 5.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 1.3;Neuroblastoma: 2.2" "Kidney - Proximal tubular cells, Pancreas - Alpha cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039025 Supported Nucleoplasm,Cytosol NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 109: Neurons - Neuronal signaling" "Nucleoplasm, Cytosol" "HPA039025: " "unprognostic (6.42e-3)" "unprognostic (3.73e-1)" "unprognostic (9.72e-3)" "unprognostic (8.80e-3)" "validated prognostic favorable (5.69e-6)" "validated prognostic favorable (1.42e-5)" "unprognostic (1.48e-2)" "unprognostic (2.22e-1)" "potential prognostic favorable (1.00e-3)" "unprognostic (4.95e-2)" "unprognostic (1.20e-1)" "unprognostic (2.42e-2)" IQUB FLJ35834 ENSG00000164675 "IQ motif and ubiquitin domain containing" Q8NA54 7 123452193-123535077 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "testis: 31.3" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 92.4;Early spermatids: 255.6;Endometrial ciliated cells: 142.3;Ependymal cells: 181.7;Fallopian tube ciliated cells: 151.8;Late primary spermatocytes: 393.6;Late spermatids: 258.8;Oocytes: 119.7;Renal collecting duct principal cells: 79.9;Renal connecting tubule cells: 98.1;Respiratory ciliated cells: 222.0" "Group enriched" "Detected in all" 4 "choroid plexus epithelial cell: 93.1;ependymal cell: 213.8" "Cancer enhanced" "Detected in some" "Kidney Renal Papillary Cell Carcinoma (TCGA): 2.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA049626 Approved "Nucleoplasm,Nuclear speckles,Cytosol,Mid piece,Principal piece,End piece" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 15: Kidney cancer - Membrane components" "Cluster 107: Ciliated cells - Cilia assembly & function" 58 "Nuclear speckles, Mid piece, Principal piece, End piece" "Nucleoplasm, Cytosol" "HPA049626: " "unprognostic (2.39e-1)" "unprognostic (9.24e-2)" "potential prognostic favorable (1.04e-11)" "unprognostic (2.13e-2)" "unprognostic (1.19e-3)" "unprognostic (2.49e-1)" "unprognostic (2.32e-1)" IRAG1 "IRAG, JAW1L, MRVI1" ENSG00000072952 "Inositol 1,4,5-triphosphate receptor associated 1" Q9Y6F6 11 10573091-10693988 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 161.7" "Cell type enhanced" "Detected in many" "Astrocytes: 183.2;Bergmann glia: 37.7;Leydig cells: 30.6;Pericytes: 105.1;Peritubular myoid cells: 46.4;Smooth muscle cells: 64.2;Vascular smooth muscle cells: 160.9" "Cell type enhanced" "Detected in many" "astrocyte: 217.4;pericyte: 97.7;vascular associated smooth muscle cell: 169.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "neutrophil: 24.0" "Lineage enriched" "Detected in many" 4 "granulocytes: 24.0" "Cancer enhanced" "Detected in some" "testis cancer: 4.1" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Heart muscle - Smooth muscle cells, Kidney - Fibroblasts, Lung - Smooth muscle cells, Minor Salivary Gland - Endothelial cells, Pituitary gland - Fibroblasts, Prostate - Smooth muscle cells, Thyroid gland - Smooth muscle cells" "Region enriched" "Detected in many" 5 "thalamus: 7.6" "Low region specificity" "Detected in all" HPA008704 Uncertain Approved "Nuclear bodies,Cytosol" NA NA 120000 "Cluster 28: Neutrophils - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 19: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 2 Cytosol "Nuclear bodies" "HPA008704: " "unprognostic (2.86e-3)" "unprognostic (2.08e-1)" "unprognostic (3.41e-1)" "unprognostic (5.16e-2)" "unprognostic (1.80e-1)" "unprognostic (3.47e-1)" "unprognostic (1.39e-1)" "unprognostic (2.04e-2)" "unprognostic (1.00e-1)" "validated prognostic favorable (6.07e-5)" "validated prognostic favorable (2.83e-4)" "potential prognostic unfavorable (3.87e-4)" "unprognostic (1.23e-2)" "unprognostic (1.57e-1)" "unprognostic (5.00e-2)" "unprognostic (2.78e-2)" "unprognostic (1.32e-2)" "unprognostic (8.81e-3)" "unprognostic (2.35e-2)" "unprognostic (1.56e-1)" "unprognostic (8.35e-2)" "unprognostic (5.52e-2)" "unprognostic (5.85e-2)" "unprognostic (1.02e-2)" "unprognostic (1.87e-2)" "unprognostic (4.08e-2)" "unprognostic (9.02e-2)" "unprognostic (6.69e-2)" "unprognostic (2.36e-1)" IRAG2 "JAW1, LRMP" ENSG00000118308 "Inositol 1,4,5-triphosphate receptor associated 2" Q12912 12 25004342-25108335 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fertilization, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 48.7;lymphoid tissue: 167.0" "Cell type enriched" "Detected in many" 4 "Tuft cells: 2686.1" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 364.4;deep-layer near-projecting: 163.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 17 "Leukemia: 162.1;lymphoma: 324.9;Myeloma: 123.7" "Breast - Endothelial cells, Kidney - Proximal tubular cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA002967, HPA007356, HPA018505" Enhanced Approved "Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 51: Neurons - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 95: Tuft cells - Chemosensory signaling" 1 "Endoplasmic reticulum, Plasma membrane" "HPA002967: , HPA007356: , HPA018505: " "unprognostic (1.72e-2)" "unprognostic (7.43e-2)" "unprognostic (1.29e-2)" "unprognostic (6.43e-2)" "unprognostic (1.34e-1)" "unprognostic (2.49e-1)" "unprognostic (3.66e-2)" "unprognostic (3.20e-2)" "unprognostic (1.88e-1)" "potential prognostic favorable (4.58e-5)" "unprognostic (7.97e-2)" "unprognostic (6.85e-2)" "unprognostic (2.48e-2)" "potential prognostic favorable (4.55e-4)" "unprognostic (9.21e-2)" "unprognostic (1.21e-1)" "unprognostic (9.10e-2)" "unprognostic (4.74e-1)" "unprognostic (1.49e-1)" "unprognostic (2.82e-2)" "unprognostic (1.49e-1)" "unprognostic (1.41e-1)" "unprognostic (7.04e-3)" "unprognostic (4.63e-2)" "unprognostic (3.25e-1)" "unprognostic (1.06e-1)" "unprognostic (4.65e-2)" "unprognostic (4.54e-2)" "unprognostic (5.06e-2)" IRAK1 "IRAK, pelle" ENSG00000184216 "Interleukin 1 receptor associated kinase 1" P51617 X 154010506-154019902 "Enzymes, Predicted intracellular proteins" "Host-virus interaction, Immunity, Innate immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Megakaryocytes: 86.5;monocytes: 90.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Macrophages, Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004461, HPA054476" Supported Supported Nucleoplasm,Cytosol No No "Cluster 29: Non-specific - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 44: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 78 Cytosol Nucleoplasm "CAB004461: , HPA054476: " "unprognostic (1.76e-1)" "unprognostic (2.47e-3)" "unprognostic (4.54e-2)" "unprognostic (2.21e-1)" "unprognostic (3.55e-2)" "unprognostic (1.63e-1)" "unprognostic (4.56e-3)" "unprognostic (2.33e-1)" "unprognostic (3.05e-2)" "unprognostic (2.03e-2)" "potential prognostic unfavorable (8.36e-4)" "unprognostic (1.12e-3)" "unprognostic (2.71e-2)" "validated prognostic unfavorable (2.10e-4)" "validated prognostic unfavorable (3.81e-4)" "unprognostic (4.42e-2)" "potential prognostic unfavorable (2.54e-4)" "unprognostic (8.35e-2)" "unprognostic (3.59e-1)" "unprognostic (3.38e-2)" "unprognostic (7.26e-3)" "unprognostic (5.18e-2)" "unprognostic (6.69e-2)" "unprognostic (1.28e-1)" "unprognostic (1.04e-2)" "unprognostic (1.11e-2)" "unprognostic (7.81e-2)" "unprognostic (9.35e-3)" "unprognostic (1.52e-1)" "unprognostic (1.11e-3)" "unprognostic (1.09e-1)" IRAK1BP1 "AIP70, SIMPL" ENSG00000146243 "Interleukin 1 receptor associated kinase 1 binding protein 1" Q5VVH5 6 78867551-78946440 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035742, HPA035743" Uncertain Approved Vesicles NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 9: Non-specific - Receptor signaling" "Cluster 32: Non-specific - Cell proliferation" "Cluster 35: Neurons - Synaptic function & neurogenesis" 8 Vesicles "HPA035742: , HPA035743: " "unprognostic (4.39e-2)" "unprognostic (1.99e-1)" "unprognostic (2.38e-1)" "unprognostic (6.80e-2)" "unprognostic (2.40e-1)" "unprognostic (1.40e-1)" "unprognostic (3.48e-1)" "unprognostic (3.62e-1)" "unprognostic (1.53e-1)" "unprognostic (4.97e-2)" "unprognostic (7.13e-3)" "unprognostic (1.83e-1)" "unprognostic (5.49e-1)" "unprognostic (2.12e-2)" "unprognostic (2.26e-2)" "unprognostic (4.09e-2)" "unprognostic (1.33e-2)" "unprognostic (4.74e-3)" "unprognostic (2.52e-1)" "unprognostic (7.54e-3)" "unprognostic (6.47e-2)" "unprognostic (1.93e-1)" "potential prognostic favorable (4.01e-4)" "unprognostic (1.81e-1)" "unprognostic (6.68e-3)" "unprognostic (1.00e-1)" "unprognostic (6.82e-2)" "unprognostic (5.21e-2)" "unprognostic (9.10e-2)" IRAK2 ENSG00000134070 "Interleukin 1 receptor associated kinase 2" O43187 3 10164919-10243745 "Enzymes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 21.9" "Cell type enhanced" "Detected in many" "cDC: 152.6;Endometrial glandular cells: 143.2;Macrophages: 131.9;monocytes: 315.4;Neutrophils: 783.1;Urothelial cells: 464.2" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 62.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Pituitary gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013483, HPA050520" Uncertain Approved Vesicles NA NA "Cluster 24: Non-specific - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 29 Vesicles "CAB013483: , HPA050520: " "unprognostic (7.34e-2)" "unprognostic (4.76e-1)" "unprognostic (2.33e-3)" "unprognostic (1.67e-1)" "unprognostic (3.59e-1)" "unprognostic (1.74e-1)" "unprognostic (7.85e-2)" "potential prognostic unfavorable (5.66e-4)" "unprognostic (2.50e-1)" "unprognostic (1.97e-2)" "unprognostic (2.61e-3)" "unprognostic (7.69e-3)" "unprognostic (3.07e-1)" "validated prognostic unfavorable (6.14e-4)" "validated prognostic unfavorable (1.22e-4)" "unprognostic (9.05e-3)" "unprognostic (3.25e-3)" "unprognostic (1.37e-1)" "unprognostic (1.58e-2)" "unprognostic (1.01e-1)" "unprognostic (2.66e-1)" "validated prognostic unfavorable (5.20e-4)" "validated prognostic unfavorable (3.99e-4)" "unprognostic (4.32e-1)" "unprognostic (2.59e-2)" "unprognostic (2.34e-3)" "unprognostic (3.82e-1)" "unprognostic (1.09e-1)" "unprognostic (4.76e-2)" "unprognostic (1.29e-1)" "unprognostic (3.43e-1)" IRAK3 IRAK-M ENSG00000090376 "Interleukin 1 receptor associated kinase 3" Q9Y616 12 66189195-66254622 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Asthma "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 73.8" "Cell type enhanced" "Detected in many" "Hematopoietic stem cells: 996.6;Monocyte progenitors: 1316.6;monocytes: 1517.4;Neutrophil progenitors: 2381.1;Neutrophils: 9249.9" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 417.8;endothelial cell: 468.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 12.7;classical monocyte: 23.5;intermediate monocyte: 24.2;myeloid DC: 11.5;neutrophil: 12.9;non-classical monocyte: 42.3" "Group enriched" "Detected in many" 12 "dendritic cells: 11.5;granulocytes: 12.9;monocytes: 42.3" "Cancer enhanced" "Detected in many" "Leukemia: 15.6" "Breast - Adipocytes (Breast), Lung - Neutrophils_2, Spleen - Neutrophils_2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA043097 Approved Approved Vesicles NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 7 Vesicles "HPA043097: " "unprognostic (1.48e-1)" "unprognostic (2.72e-1)" "unprognostic (1.07e-1)" "unprognostic (2.50e-1)" "unprognostic (3.43e-1)" "unprognostic (4.83e-2)" "unprognostic (4.61e-1)" "unprognostic (2.09e-1)" "unprognostic (3.31e-2)" "potential prognostic favorable (4.50e-4)" "unprognostic (7.90e-3)" "unprognostic (1.43e-1)" "unprognostic (4.55e-2)" "unprognostic (1.59e-1)" "unprognostic (1.41e-2)" "unprognostic (6.35e-3)" "unprognostic (1.54e-2)" "unprognostic (8.43e-2)" "unprognostic (2.76e-2)" "unprognostic (2.63e-1)" "unprognostic (1.13e-1)" "unprognostic (7.30e-2)" "unprognostic (1.24e-3)" "unprognostic (1.22e-1)" "unprognostic (4.54e-2)" "unprognostic (1.18e-1)" "unprognostic (2.38e-2)" IRAK4 NY-REN-64 ENSG00000198001 "Interleukin 1 receptor associated kinase 4" Q9NWZ3 12 43758944-43798307 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Immunity, Innate immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 159.8;Neutrophils: 173.6" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 80.0;leukocyte: 76.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB016685, CAB022077" Uncertain Supported "Nucleoli,Plasma membrane,Microtubules,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 21: Non-specific - Metabolism" "Cluster 38: Non-specific - Transcription" "Cluster 24: Neutrophils - Innate immunity signal integration" 21 "Microtubules, Cytosol" "Nucleoli, Plasma membrane" "CAB016685: , CAB022077: " "unprognostic (1.00e-2)" "unprognostic (1.42e-2)" "unprognostic (2.06e-1)" "unprognostic (1.91e-1)" "unprognostic (2.28e-1)" "unprognostic (1.94e-1)" "unprognostic (1.70e-1)" "potential prognostic unfavorable (6.71e-4)" "unprognostic (2.53e-2)" "unprognostic (1.67e-3)" "unprognostic (5.94e-3)" "unprognostic (2.40e-1)" "unprognostic (1.09e-3)" "unprognostic (4.11e-3)" "unprognostic (2.09e-3)" "unprognostic (1.77e-1)" "unprognostic (1.47e-2)" "unprognostic (1.29e-1)" "unprognostic (1.14e-1)" "unprognostic (1.22e-1)" "unprognostic (2.94e-1)" "unprognostic (1.48e-2)" "unprognostic (5.66e-2)" "unprognostic (1.83e-1)" "unprognostic (1.17e-2)" "unprognostic (4.93e-2)" "unprognostic (1.02e-2)" "unprognostic (2.20e-1)" "unprognostic (5.28e-2)" "unprognostic (2.12e-1)" "unprognostic (3.79e-2)" IREB2 IRP2 ENSG00000136381 "Iron responsive element binding protein 2" P48200 15 78437431-78501453 "Disease related genes, Plasma proteins, Predicted intracellular proteins" RNA-binding "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adrenal cortex cells: 266.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032885, HPA040371, HPA068982" Uncertain Approved "Cell Junctions,Cytosol" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 16: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 18: Adrenal cortex cells - Steroidogensis" 17 "Cell Junctions" Cytosol "CAB032885: , HPA040371: , HPA068982: " "unprognostic (1.38e-2)" "unprognostic (3.06e-2)" "unprognostic (4.58e-1)" "unprognostic (7.17e-3)" "unprognostic (1.29e-1)" "unprognostic (5.08e-2)" "unprognostic (4.45e-2)" "unprognostic (7.84e-3)" "unprognostic (2.81e-1)" "unprognostic (1.17e-2)" "potential prognostic favorable (3.59e-5)" "unprognostic (6.18e-3)" "unprognostic (2.73e-1)" "unprognostic (1.38e-1)" "unprognostic (7.16e-2)" "unprognostic (1.29e-1)" "unprognostic (4.70e-2)" "unprognostic (1.83e-1)" "unprognostic (3.70e-2)" "unprognostic (1.98e-1)" "unprognostic (8.45e-2)" "unprognostic (4.27e-2)" "unprognostic (3.47e-3)" "unprognostic (5.16e-2)" "unprognostic (9.91e-3)" "unprognostic (2.11e-1)" "unprognostic (1.08e-1)" "unprognostic (4.10e-1)" "unprognostic (1.55e-1)" "unprognostic (6.40e-3)" "unprognostic (1.09e-1)" IRF1 MAR ENSG00000125347 "Interferon regulatory factor 1" P10914 5 132440440-132508719 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Antiviral defense, Immunity, Innate immunity, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 134.1" "Cell type enhanced" "Detected in many" "Epididymal basal cells: 584.9;Neutrophils: 755.6;Salivary myoepithelial cells: 620.6;Smooth muscle cells: 567.8" "Group enriched" "Detected in all" 4 "endothelial cell: 56.0;leukocyte: 119.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011662, HPA063131, HPA070953" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 20: Non-specific - Transcription regulation" 23 Nucleoplasm Cytosol "CAB011662: , HPA063131: , HPA070953: " "unprognostic (1.83e-1)" "unprognostic (8.22e-3)" "unprognostic (9.90e-2)" "unprognostic (1.66e-1)" "unprognostic (4.05e-2)" "unprognostic (4.51e-2)" "unprognostic (1.18e-1)" "unprognostic (1.50e-1)" "unprognostic (5.67e-2)" "unprognostic (3.59e-2)" "unprognostic (2.38e-2)" "unprognostic (2.00e-1)" "unprognostic (2.03e-3)" "unprognostic (3.94e-1)" "unprognostic (3.52e-2)" "unprognostic (8.59e-2)" "unprognostic (1.94e-1)" "unprognostic (1.86e-2)" "unprognostic (4.83e-1)" "unprognostic (1.42e-1)" "unprognostic (6.33e-3)" "unprognostic (6.93e-2)" "unprognostic (1.64e-1)" "unprognostic (2.54e-1)" "unprognostic (9.29e-3)" "unprognostic (8.19e-2)" "unprognostic (1.36e-2)" "unprognostic (3.32e-2)" "unprognostic (1.81e-1)" "unprognostic (1.75e-1)" "unprognostic (1.80e-1)" IRF2 ENSG00000168310 "Interferon regulatory factor 2" P14316 4 184385702-184474558 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 377.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030813, CAB032306, HPA057327" Supported Enhanced "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 25: Non-specific - Transcription" "Cluster 55: Lymphoma - Immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 24 Nucleoplasm "Cell Junctions, Cytosol" "CAB032306: , HPA030813: , HPA057327: " "unprognostic (2.52e-3)" "unprognostic (8.08e-3)" "unprognostic (2.27e-1)" "unprognostic (2.37e-1)" "unprognostic (2.90e-1)" "unprognostic (1.21e-1)" "unprognostic (2.35e-1)" "unprognostic (3.65e-1)" "unprognostic (7.32e-2)" "unprognostic (7.23e-2)" "unprognostic (1.10e-3)" "unprognostic (2.05e-2)" "unprognostic (2.30e-1)" "unprognostic (4.04e-3)" "unprognostic (2.43e-2)" "unprognostic (4.23e-1)" "unprognostic (5.69e-2)" "unprognostic (1.87e-1)" "unprognostic (1.25e-1)" "unprognostic (7.20e-2)" "unprognostic (2.17e-1)" "unprognostic (1.45e-2)" "unprognostic (2.14e-1)" "unprognostic (1.17e-1)" "unprognostic (4.33e-2)" "unprognostic (2.18e-1)" "unprognostic (5.20e-2)" "unprognostic (1.18e-2)" "unprognostic (3.73e-2)" "unprognostic (6.24e-2)" "unprognostic (6.38e-2)" IRF2BP1 "DKFZP434M154, IRF-2BP1" ENSG00000170604 "Interferon regulatory factor 2 binding protein 1" Q8IU81 19 45883608-45886141 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042164, HPA049480" Approved Supported Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 24: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 16 Nucleoplasm "HPA042164: , HPA049480: " "potential prognostic favorable (1.07e-4)" "unprognostic (1.09e-1)" "unprognostic (2.78e-1)" "unprognostic (3.83e-1)" "unprognostic (1.07e-1)" "unprognostic (2.53e-1)" "unprognostic (1.98e-1)" "unprognostic (1.32e-1)" "unprognostic (3.50e-2)" "unprognostic (4.89e-2)" "potential prognostic favorable (9.82e-5)" "unprognostic (2.79e-3)" "unprognostic (2.83e-2)" "unprognostic (8.84e-2)" "unprognostic (2.77e-1)" "unprognostic (5.72e-3)" "unprognostic (9.73e-2)" "unprognostic (1.21e-2)" "unprognostic (4.02e-3)" "unprognostic (4.96e-2)" "unprognostic (1.61e-1)" "potential prognostic favorable (2.28e-4)" "unprognostic (5.75e-3)" "unprognostic (9.60e-2)" "unprognostic (4.58e-1)" "unprognostic (1.05e-1)" "unprognostic (1.18e-1)" "unprognostic (8.14e-2)" "unprognostic (1.49e-1)" "unprognostic (2.07e-1)" "unprognostic (1.10e-2)" IRF2BP2 IRF-2BP2 ENSG00000168264 "Interferon regulatory factor 2 binding protein 2" Q7Z5L9 1 234604269-234610178 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027815, HPA062269" Approved Enhanced Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 15: Bone marrow - Innate immune response" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 15 Nucleoplasm "HPA027815: , HPA062269: " "unprognostic (1.37e-2)" "unprognostic (1.32e-2)" "unprognostic (3.33e-1)" "unprognostic (2.35e-2)" "unprognostic (7.20e-2)" "unprognostic (5.17e-2)" "unprognostic (8.49e-2)" "unprognostic (2.64e-2)" "unprognostic (1.85e-1)" "unprognostic (1.07e-1)" "validated prognostic favorable (6.33e-7)" "validated prognostic favorable (8.72e-6)" "unprognostic (2.97e-1)" "unprognostic (1.14e-3)" "unprognostic (1.47e-1)" "unprognostic (1.03e-1)" "unprognostic (1.28e-1)" "unprognostic (3.04e-1)" "unprognostic (1.98e-1)" "unprognostic (9.24e-2)" "unprognostic (1.07e-1)" "unprognostic (1.17e-1)" "unprognostic (2.80e-2)" "unprognostic (8.53e-2)" "unprognostic (1.66e-1)" "unprognostic (3.57e-1)" "unprognostic (7.32e-2)" "unprognostic (2.16e-1)" "unprognostic (1.64e-1)" "unprognostic (4.35e-2)" "unprognostic (1.32e-1)" IRF2BPL "C14orf4, EAP1, KIAA1865" ENSG00000119669 "Interferon regulatory factor 2 binding protein like" Q9H1B7 14 77024543-77028708 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 172.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050862, HPA061333" Approved Enhanced "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 30: Non-specific - DNA binding" "Cluster 74: Non-specific - Signal transduction" "Cluster 46: Brainstem - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" 14 Nucleoplasm "Nuclear bodies" "HPA050862: , HPA061333: " "unprognostic (1.84e-2)" "unprognostic (1.82e-1)" "unprognostic (2.67e-2)" "unprognostic (1.28e-1)" "unprognostic (3.23e-2)" "unprognostic (8.25e-2)" "unprognostic (3.42e-1)" "unprognostic (1.86e-2)" "unprognostic (6.76e-2)" "unprognostic (2.87e-3)" "unprognostic (1.95e-2)" "unprognostic (1.73e-1)" "unprognostic (8.16e-2)" "unprognostic (9.78e-2)" "unprognostic (1.51e-1)" "unprognostic (6.52e-2)" "unprognostic (1.37e-1)" "unprognostic (1.80e-3)" "unprognostic (1.52e-2)" "unprognostic (1.24e-2)" "unprognostic (5.75e-3)" "unprognostic (2.48e-2)" "unprognostic (1.55e-1)" "unprognostic (2.45e-1)" "unprognostic (1.35e-1)" "unprognostic (1.56e-1)" "unprognostic (7.06e-2)" "unprognostic (2.75e-1)" "unprognostic (1.94e-2)" "unprognostic (3.21e-2)" IRF3 ENSG00000126456 "Interferon regulatory factor 3" Q14653 19 49659569-49665875 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004895, CAB013018" Approved Supported Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 65: Non-specific - Cell growth & division" 52 Cytosol "CAB013018: , HPA004895: " "unprognostic (1.26e-1)" "unprognostic (3.44e-1)" "potential prognostic favorable (4.14e-5)" "unprognostic (2.91e-2)" "unprognostic (1.70e-2)" "unprognostic (7.69e-2)" "unprognostic (1.24e-1)" "unprognostic (5.92e-2)" "unprognostic (2.35e-1)" "unprognostic (1.40e-3)" "unprognostic (3.40e-3)" "unprognostic (1.68e-1)" "unprognostic (7.41e-2)" "potential prognostic unfavorable (2.49e-5)" "unprognostic (9.12e-3)" "unprognostic (1.17e-1)" "unprognostic (1.06e-1)" "unprognostic (2.05e-1)" "unprognostic (1.63e-1)" "unprognostic (2.96e-2)" "unprognostic (2.29e-1)" "unprognostic (1.19e-1)" "unprognostic (2.09e-1)" "unprognostic (8.47e-2)" "unprognostic (2.34e-1)" "unprognostic (1.89e-2)" "unprognostic (1.17e-1)" "unprognostic (3.19e-2)" "unprognostic (2.61e-2)" "unprognostic (3.45e-1)" "unprognostic (6.20e-2)" IRF4 "LSIRF, MUM1" ENSG00000137265 "Interferon regulatory factor 4" Q15306 6 391739-411443 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 38.6;lymphoid tissue: 24.5" "Cell type enhanced" "Detected in some" "B-cells: 107.0;cDC: 123.5;Innate lymphoid cells: 95.7;Melanocytes: 167.3;pDCs: 596.3;Plasma cells: 360.5;T-cells: 67.8" "Cell type enriched" "Detected in some" 22 "leukocyte: 30.2" "Cancer enriched" "Detected in many" 10 "Skin Cutaneous Melanoma (TCGA): 42.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "memory B-cell: 10.6;myeloid DC: 11.0;naive B-cell: 11.1;plasmacytoid DC: 12.7;T-reg: 5.9" "Group enriched" "Detected in many" 5 "B-cells: 11.1;dendritic cells: 12.7;T-cells: 5.9" "Group enriched" "Detected in some" 10 "lymphoma: 164.6;Myeloma: 389.3" "Minor Salivary Gland - Plasma cells, Stomach - Plasma cells, Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA002038, HPA002698, CAB013508" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 21 Nucleoplasm Cytosol "CAB013508: , HPA002038: , HPA002698: " "unprognostic (3.60e-3)" "unprognostic (3.08e-2)" "unprognostic (1.05e-3)" "unprognostic (2.00e-2)" "unprognostic (2.40e-1)" "unprognostic (2.04e-2)" "potential prognostic favorable (1.15e-6)" "unprognostic (3.45e-3)" "unprognostic (5.60e-2)" "unprognostic (4.86e-2)" "unprognostic (7.52e-3)" "potential prognostic favorable (1.95e-4)" "unprognostic (7.72e-2)" "unprognostic (1.63e-1)" "unprognostic (2.70e-2)" "potential prognostic unfavorable (8.43e-4)" "unprognostic (1.68e-2)" "unprognostic (3.65e-1)" "unprognostic (5.14e-2)" "unprognostic (1.38e-1)" "unprognostic (4.47e-2)" "unprognostic (2.49e-1)" IRF5 IRF-5 ENSG00000128604 "Interferon regulatory factor 5" Q13568 7 128937457-128950038 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Antiviral defense, Immunity, Inflammatory response, Innate immunity, Transcription, Transcription regulation" DNA-binding "Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "cDC: 28.5;Esophageal apical cells: 21.2;Esophageal suprabasal cells: 20.1;Hofbauer cells: 48.1;Kupffer cells: 30.7;Macrophages: 32.4;Megakaryocytes: 24.7;Microglia: 50.6;Monocyte progenitors: 39.9;monocytes: 39.2" "Cell type enriched" "Detected in some" 7 "central nervous system macrophage: 55.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 8 "B-cells: 16.1;dendritic cells: 42.1;monocytes: 50.6" "Cancer enhanced" "Detected in many" "lymphoma: 46.8" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Heart muscle - Macrophages, Lung - Macrophages, Skeletal muscle - Macrophages, Testis - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046700, HPA076024" Enhanced NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 25 "HPA046700: , HPA076024: " "unprognostic (1.27e-1)" "unprognostic (8.77e-2)" "unprognostic (1.50e-1)" "unprognostic (2.35e-2)" "unprognostic (7.01e-3)" "unprognostic (1.40e-1)" "unprognostic (2.51e-1)" "unprognostic (1.34e-1)" "unprognostic (1.49e-1)" "unprognostic (4.78e-2)" "unprognostic (1.22e-1)" "unprognostic (1.74e-3)" "unprognostic (2.77e-1)" "unprognostic (4.34e-2)" "unprognostic (2.79e-1)" "unprognostic (6.23e-2)" "unprognostic (1.01e-1)" "unprognostic (4.43e-1)" "unprognostic (1.43e-1)" "unprognostic (3.85e-1)" "unprognostic (2.40e-1)" "unprognostic (2.44e-1)" "unprognostic (6.84e-2)" "unprognostic (1.65e-1)" "unprognostic (3.56e-1)" "unprognostic (2.05e-1)" "unprognostic (1.59e-1)" "unprognostic (2.65e-1)" "unprognostic (1.56e-2)" "unprognostic (2.19e-1)" "unprognostic (2.49e-3)" IRF6 "LPS, OFC6, VWS, VWS1" ENSG00000117595 "Interferon regulatory factor 6" O14896 1 209785617-209806175 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 86.6;skin 1: 104.1" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 17.3;Ependymal cells: 6.1;Loop of henle epithelial cells: 8.7;Papillary tip epithelial cells: 39.6;Proximal tubule cells: 7.0;Renal collecting duct intercalated cells: 25.7;Renal collecting duct principal cells: 14.5;Renal connecting tubule cells: 14.2" "Cell type enhanced" "Detected in some" "cerebellar inhibitory: 7.6;endothelial cell: 8.1;ependymal cell: 7.9" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "cerebellum: 20.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 108.8" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal cortex cells, Breast - Breast myoepithelial cells, Colon - Colon enterocytes, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary gland basal cells, Skin - Keratinocyte (other), Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA063121, HPA076162" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 58: Skin - Keratinization" "Cluster 35: Non-specific - DNA binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 4 Cytosol Nucleoplasm "HPA063121: , HPA076162: " "unprognostic (1.01e-1)" "unprognostic (9.31e-2)" "unprognostic (3.20e-2)" "unprognostic (1.63e-2)" "unprognostic (1.81e-1)" "unprognostic (6.02e-2)" "unprognostic (3.09e-2)" "unprognostic (3.71e-2)" "unprognostic (4.26e-1)" "validated prognostic favorable (5.53e-10)" "validated prognostic favorable (2.79e-5)" "unprognostic (4.47e-3)" "unprognostic (1.27e-1)" "unprognostic (4.46e-3)" "unprognostic (2.92e-1)" "unprognostic (7.34e-2)" "unprognostic (2.36e-1)" "unprognostic (2.85e-1)" "unprognostic (4.18e-2)" "unprognostic (3.43e-3)" "unprognostic (1.95e-3)" "unprognostic (3.01e-1)" "unprognostic (1.53e-1)" "unprognostic (6.58e-2)" "unprognostic (8.40e-2)" "unprognostic (7.93e-3)" "unprognostic (2.17e-1)" "unprognostic (4.54e-3)" "unprognostic (1.57e-1)" "unprognostic (3.29e-1)" IRF7 ENSG00000185507 "Interferon regulatory factor 7" Q92985 11 612553-615983 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 38.7;lymphoid tissue: 33.5" "Cell type enriched" "Detected in many" 14 "pDCs: 790.3" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 19.1;endothelial cell: 34.4;leukocyte: 19.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in all" 12 "plasmacytoid DC: 597.5" "Lineage enriched" "Detected in all" 12 "dendritic cells: 597.5" "Low cancer specificity" "Detected in many" "Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017694, HPA052757" Approved Supported Nucleoplasm,Cytosol No NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 70: Non-specific - Protein processing" "Cluster 8: Immune cells - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 40 Nucleoplasm Cytosol "CAB017694: , HPA052757: " "unprognostic (1.02e-3)" "unprognostic (3.07e-2)" "unprognostic (5.34e-2)" "unprognostic (7.67e-3)" "unprognostic (8.36e-2)" "unprognostic (2.43e-2)" "unprognostic (3.09e-1)" "unprognostic (4.49e-2)" "unprognostic (1.17e-1)" "unprognostic (7.30e-2)" "unprognostic (9.18e-2)" "unprognostic (5.63e-2)" "unprognostic (1.05e-3)" "unprognostic (4.86e-3)" "unprognostic (3.06e-3)" "unprognostic (2.11e-2)" "unprognostic (3.54e-2)" "unprognostic (1.97e-1)" "unprognostic (1.04e-3)" "unprognostic (4.01e-3)" "unprognostic (4.59e-3)" "unprognostic (2.88e-2)" "unprognostic (3.82e-1)" "potential prognostic unfavorable (2.55e-4)" "unprognostic (2.43e-1)" "unprognostic (2.52e-1)" "unprognostic (1.92e-1)" "unprognostic (2.39e-3)" "unprognostic (1.55e-2)" IRF8 "ICSBP, ICSBP1, IRF-8" ENSG00000140968 "Interferon regulatory factor 8" Q02556 16 85899116-85922606 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Autophagy, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 195.7" "Cell type enhanced" "Detected in many" "B-cells: 389.8;cDC: 357.1;Kupffer cells: 197.8;Macrophages: 158.9;Microglia: 182.7;Monocyte progenitors: 158.1;monocytes: 151.6;pDCs: 1306.7;Thymocytes: 107.6" "Cell type enriched" "Detected in some" 11 "central nervous system macrophage: 202.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "plasmacytoid DC: 2405.3" "Lineage enriched" "Detected in all" 7 "dendritic cells: 2405.3" "Group enriched" "Detected in many" 8 "Leukemia: 59.6;lymphoma: 187.3" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Macrophages, Lung - Macrophages, Minor Salivary Gland - Macrophages, Skeletal muscle - Macrophages, Spleen - B-cells (Spleen), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002267, HPA002531, CAB013480" Enhanced Enhanced Nucleoplasm NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 8 Nucleoplasm "CAB013480: , HPA002267: , HPA002531: " "unprognostic (2.77e-3)" "unprognostic (1.12e-2)" "unprognostic (5.75e-2)" "unprognostic (3.04e-1)" "unprognostic (2.37e-1)" "unprognostic (1.52e-3)" "unprognostic (1.82e-1)" "unprognostic (1.81e-2)" "unprognostic (3.17e-3)" "unprognostic (2.61e-1)" "unprognostic (3.29e-3)" "unprognostic (1.53e-2)" "unprognostic (8.53e-2)" "unprognostic (7.16e-2)" "unprognostic (1.14e-2)" "potential prognostic favorable (2.23e-4)" "unprognostic (3.98e-2)" "unprognostic (2.21e-1)" "unprognostic (2.86e-1)" "unprognostic (2.26e-1)" "unprognostic (2.10e-1)" "unprognostic (1.04e-1)" "unprognostic (3.42e-2)" "unprognostic (6.63e-2)" "unprognostic (1.23e-2)" "unprognostic (1.77e-1)" "unprognostic (1.08e-1)" "unprognostic (4.85e-1)" "unprognostic (2.83e-2)" "unprognostic (8.13e-2)" "unprognostic (1.62e-1)" IRF9 ISGF3G ENSG00000213928 "Interferon regulatory factor 9" Q00978 14 24161234-24168043 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Antiviral defense, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 29.8;Bergmann glia: 22.3;Ependymal cells: 26.2;Microglia: 50.2;Oligodendrocyte progenitor cells: 54.8;Oligodendrocytes: 19.1;Other brain neurons: 17.2;Tuft cells: 11.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001862 Approved Supported Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 5: Spleen - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 22: Non-specific - Basic cellular functions" 10 Cytosol "HPA001862: " "unprognostic (3.34e-2)" "unprognostic (8.67e-2)" "unprognostic (3.13e-1)" "unprognostic (2.67e-1)" "unprognostic (4.13e-1)" "unprognostic (1.49e-1)" "unprognostic (1.25e-1)" "unprognostic (2.50e-2)" "unprognostic (5.96e-2)" "unprognostic (7.55e-2)" "potential prognostic favorable (1.83e-6)" "unprognostic (4.99e-3)" "unprognostic (1.31e-1)" "unprognostic (2.38e-1)" "unprognostic (6.53e-3)" "unprognostic (1.39e-1)" "unprognostic (1.68e-2)" "unprognostic (1.52e-1)" "unprognostic (2.93e-1)" "unprognostic (9.99e-2)" "potential prognostic favorable (6.99e-4)" "unprognostic (1.15e-3)" "unprognostic (1.01e-3)" "unprognostic (1.16e-1)" "unprognostic (2.28e-2)" "unprognostic (1.70e-1)" "unprognostic (2.10e-2)" "unprognostic (2.16e-1)" "unprognostic (2.86e-1)" "potential prognostic favorable (4.85e-4)" "unprognostic (8.27e-2)" IRGC "CINEMA, Iigp5, IRGC1" ENSG00000124449 "Immunity related GTPase cinema" Q6NXR0 19 43716076-43720021 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 791 "testis: 148.6" "Group enriched" "Detected in some" 7 "Early spermatids: 1769.5;Late spermatids: 3335.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA046769, HPA060064" Enhanced NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 1 "HPA046769: , HPA060064: " IRGM "IFI1, IRGM1, LRG-47, LRG47" ENSG00000237693 "Immunity related GTPase M" A1A4Y4 5 150846521-150900736 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Autophagy, Immunity, Inflammatory response, Innate immunity" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Adipocytes: 10.2;Epicardial cells: 31.8;Hematopoietic stem cells: 17.5;Innate lymphoid cells: 9.7;Late primary spermatocytes: 16.9;Mast cells: 13.8;Oocytes: 9.2;T-cells: 13.7;Thymocytes: 44.0" "Group enriched" "Detected in some" 5 "deep-layer corticothalamic and 6b: 4.9;leukocyte: 13.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "basophil: 2.3" "Lineage enriched" "Detected in single" 5 "granulocytes: 2.3" "Cancer enriched" "Detected in single" 4 "Leukemia: 2.0" NA NA "Cluster 48: Non-specific - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 20: Non-specific - Transcription regulation" 13 IRGQ "FKSG27, IRGQ1" ENSG00000167378 "Immunity related GTPase Q" Q8WZA9 19 43584367-43596134 "Predicted intracellular proteins" Autophagy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hematopoietic stem cells: 4.9;Late spermatids: 5.0;Retinal ganglion cells: 7.7;Tuft cells: 11.5" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043254, HPA050338" Approved Approved Vesicles NA NA 33000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 65: Non-specific - Cell growth & division" 6 Vesicles "HPA043254: , HPA050338: " "unprognostic (7.89e-3)" "unprognostic (6.29e-2)" "unprognostic (1.15e-1)" "unprognostic (3.23e-2)" "unprognostic (2.10e-1)" "unprognostic (4.98e-2)" "unprognostic (3.15e-1)" "unprognostic (4.52e-2)" "unprognostic (1.51e-2)" "unprognostic (3.99e-2)" "unprognostic (2.21e-3)" "unprognostic (2.18e-3)" "unprognostic (2.32e-1)" "unprognostic (9.85e-2)" "unprognostic (2.54e-1)" "unprognostic (1.55e-1)" "unprognostic (2.99e-2)" "unprognostic (1.30e-2)" "unprognostic (6.21e-2)" "unprognostic (3.95e-1)" "unprognostic (1.39e-2)" "unprognostic (1.50e-1)" "unprognostic (1.70e-1)" "unprognostic (1.10e-2)" "potential prognostic favorable (6.89e-4)" "unprognostic (1.37e-1)" "unprognostic (1.02e-1)" "unprognostic (3.51e-1)" "unprognostic (8.47e-3)" "unprognostic (1.73e-1)" IRS1 HIRS-1 ENSG00000169047 "Insulin receptor substrate 1" P35568 2 226731312-226799820 "Disease related genes, Plasma proteins, Predicted intracellular proteins" Transducer "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 166.1;Adrenal cortex cells: 122.4;Breast lactating cells: 120.0;Renal collecting duct intercalated cells: 137.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Lung - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005261, HPA046433" Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 2: Neurons - Nucleosome" "Cluster 72: Neuronal - Signal transduction" "Cluster 89: Adipocytes - Lipid metabolism" 58 "Nucleoplasm, Cytosol" "Vesicles, Plasma membrane" "CAB005261: , HPA046433: " "unprognostic (6.97e-3)" "unprognostic (1.09e-1)" "potential prognostic favorable (5.38e-4)" "unprognostic (5.67e-3)" "unprognostic (1.63e-1)" "unprognostic (9.98e-2)" "unprognostic (2.93e-2)" "unprognostic (5.20e-2)" "unprognostic (1.64e-1)" "unprognostic (2.05e-1)" "unprognostic (2.35e-2)" "unprognostic (2.08e-1)" "unprognostic (6.22e-2)" "unprognostic (1.29e-1)" "unprognostic (2.97e-1)" "unprognostic (3.19e-3)" "unprognostic (4.11e-3)" "unprognostic (3.82e-2)" "unprognostic (5.37e-2)" "unprognostic (9.47e-3)" "unprognostic (3.53e-2)" "unprognostic (1.40e-2)" "unprognostic (1.83e-1)" "unprognostic (5.77e-2)" "unprognostic (1.62e-1)" "unprognostic (7.72e-2)" "unprognostic (9.93e-2)" "unprognostic (3.73e-2)" "unprognostic (1.60e-1)" "unprognostic (4.50e-2)" "unprognostic (2.22e-2)" IRS2 ENSG00000185950 "Insulin receptor substrate 2" Q9Y4H2 13 109752695-109786583 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Transducer "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 48.4" "Cell type enhanced" "Detected in all" "Monocyte progenitors: 732.0;monocytes: 574.1;Neutrophil progenitors: 778.1;Neutrophils: 2931.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 3.3" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.3" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016944, HPA054664" Approved Supported Aggresome,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 51: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 36 Cytosol Aggresome "CAB016944: , HPA054664: " "unprognostic (5.53e-3)" "unprognostic (9.75e-3)" "unprognostic (6.55e-2)" "unprognostic (8.76e-3)" "unprognostic (1.64e-1)" "potential prognostic unfavorable (3.53e-5)" "unprognostic (2.83e-1)" "unprognostic (1.38e-1)" "unprognostic (1.14e-2)" "unprognostic (1.04e-1)" "unprognostic (7.52e-2)" "unprognostic (9.26e-2)" "unprognostic (6.62e-2)" "unprognostic (8.72e-2)" "unprognostic (6.97e-2)" "unprognostic (3.33e-2)" "unprognostic (1.44e-2)" "unprognostic (9.42e-2)" "unprognostic (2.71e-1)" "unprognostic (4.98e-3)" "unprognostic (1.26e-3)" "unprognostic (1.73e-1)" "unprognostic (2.72e-3)" "unprognostic (8.68e-2)" "unprognostic (5.43e-2)" "unprognostic (5.56e-2)" "unprognostic (1.89e-1)" "unprognostic (2.68e-1)" "unprognostic (1.79e-1)" "unprognostic (4.13e-2)" "unprognostic (1.43e-1)" IRS4 "IRS-4, PY160" ENSG00000133124 "Insulin receptor substrate 4" O14654 X 108719946-108736563 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" Transducer "Cancer-related genes, Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 6.0;pituitary gland: 23.6" "Cell type enhanced" "Detected in some" "Gonadotrophs: 111.7;Lactotrophs: 84.7;Medullary thymic epithelial cells: 28.8;Somatotrophs: 408.9;Thyrotrophs: 152.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Breast Invasive Carcinoma (TCGA): 2.3;Lung Squamous Cell Carcinoma (TCGA): 2.8" "Region enhanced" "Detected in many" "hypothalamus: 31.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 14 "Rhabdoid: 52.0" "Lung - Respiratory ciliated cells, Testis - Spermatogonia" "Group enriched" "Detected in many" 5 "basal ganglia: 11.7;hypothalamus: 45.0" "Group enriched" "Detected in many" 6 "basal ganglia: 17.6;hypothalamus: 44.1" HPA017372 Uncertain NA NA "Cluster 20: Pituitary gland - Hormone signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 3: Rhabdoid - Membrane components" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 73 "HPA017372: " "unprognostic (6.22e-3)" "potential prognostic favorable (2.29e-4)" "unprognostic (2.21e-3)" IRX1 IRX-5 ENSG00000170549 "Iroquois homeobox 1" P78414 5 3595832-3601403 "Plasma proteins, Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 13.5;kidney: 23.2;salivary gland: 15.4" "Cell type enhanced" "Detected in some" "Bergmann glia: 38.1;Breast lactating cells: 231.2;Breast myoepithelial cells: 111.1;Breast secretory cells: 64.0;Loop of henle epithelial cells: 27.5;Salivary basal cells: 25.4;Salivary myoepithelial cells: 37.5" "Group enriched" "Detected in some" 5 "astrocyte: 14.2;Bergmann glia: 43.3;ependymal cell: 16.9;lower rhombic lip: 30.8;oligodendrocyte precursor cell: 11.6" "Group enriched" "Detected in many" 5 "Breast Invasive Carcinoma (TCGA): 7.7;Glioblastoma Multiforme (TCGA): 10.9;Testicular Germ Cell Tumor (TCGA): 22.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 5.1;Leukemia: 8.3" "Pancreas - Alpha cells, Pituitary gland - Gonadotropes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA043160 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 49: Hindbrain - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 4: Breast lactating luminal cells - Lactation" "Golgi apparatus" Nucleoplasm "HPA043160: " "unprognostic (3.97e-2)" "unprognostic (2.34e-1)" "unprognostic (5.32e-3)" "unprognostic (5.99e-3)" "unprognostic (3.12e-1)" "unprognostic (3.40e-3)" "unprognostic (1.32e-3)" "unprognostic (1.91e-2)" "unprognostic (5.28e-3)" "unprognostic (3.59e-2)" IRX2 ENSG00000170561 "Iroquois homeobox 2" Q9BZI1 5 2745845-2751677 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 22.5;salivary gland: 26.8;skin 1: 24.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 253.4;Alveolar cells type 2: 132.0;Basal keratinocytes: 154.8;Breast hormone-responsive cells: 108.8;Breast lactating cells: 798.3;Breast myoepithelial cells: 216.1;Gastric chief cells: 173.6;Pancreatic islet cells: 194.4;Parietal cells: 113.1;Salivary basal cells: 104.3;Transitional alveolar cells: 149.0" "Cell type enhanced" "Detected in some" "Bergmann glia: 78.1;lower rhombic lip: 89.3" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 25.7" "Region enhanced" "Detected in many" "pons: 46.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 33.5" "Pancreas - Alpha cells, Stomach - Chief cells, Testis - Spermatogonia" "Group enriched" "Detected in many" 5 "midbrain: 26.5;pons and medulla: 20.9;thalamus: 11.2" "Region enhanced" "Detected in many" "pons: 8.0" "HPA050895, HPA054669" Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 58: Skin - Keratinization" "Cluster 49: Hindbrain - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 4: Breast lactating luminal cells - Lactation" 2 "Nucleoplasm, Nucleoli" "HPA050895: , HPA054669: " "unprognostic (2.17e-1)" "unprognostic (9.60e-2)" "unprognostic (3.16e-1)" "unprognostic (2.82e-1)" "unprognostic (3.78e-2)" "unprognostic (2.39e-1)" "unprognostic (5.09e-2)" "potential prognostic favorable (1.19e-4)" "unprognostic (3.69e-3)" "potential prognostic favorable (1.57e-4)" "unprognostic (1.09e-1)" "unprognostic (3.19e-2)" "unprognostic (4.05e-1)" "potential prognostic favorable (1.76e-4)" "unprognostic (2.00e-2)" "unprognostic (1.03e-2)" "unprognostic (1.60e-1)" "potential prognostic unfavorable (9.39e-4)" "unprognostic (1.20e-1)" "unprognostic (2.12e-2)" "unprognostic (1.66e-1)" "unprognostic (5.62e-2)" IRX3 IRX-1 ENSG00000177508 "Iroquois homeobox 3" P78415 16 54283304-54286787 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 70.8;skin 1: 83.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 165.9;Basal prostatic cells: 136.8;Breast hormone-responsive cells: 181.4;Breast lactating cells: 279.6;Breast secretory cells: 128.1;Endometrial glandular cells: 142.7;Epididymal principal cells: 210.2;Fallopian tube ciliated cells: 128.2;Platelets: 234.2;Respiratory ciliated cells: 163.0" "Cell type enhanced" "Detected in some" "astrocyte: 17.9;Bergmann glia: 23.5;ependymal cell: 46.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 44.1" "Breast - Breast glandular cells, Breast - Breast glandular cells, Kidney - Endothelial cells, Lung - Alveolar cells type 2, Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA066576 Approved Nucleoplasm,Cytosol NA NA "Cluster 58: Skin - Keratinization" "Cluster 44: Non-specific - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 51: Secretory epithelial cells - Mixed function" Nucleoplasm Cytosol "HPA066576: " "unprognostic (1.08e-1)" "unprognostic (4.33e-2)" "unprognostic (9.44e-2)" "unprognostic (2.26e-1)" "unprognostic (3.80e-2)" "unprognostic (1.47e-1)" "unprognostic (3.14e-2)" "unprognostic (7.47e-2)" "unprognostic (2.63e-1)" "unprognostic (5.32e-1)" "unprognostic (2.79e-2)" "unprognostic (1.14e-1)" "potential prognostic favorable (2.24e-4)" "unprognostic (2.01e-2)" "unprognostic (3.56e-1)" "unprognostic (2.19e-3)" "unprognostic (2.07e-2)" "unprognostic (4.27e-2)" "unprognostic (2.21e-1)" "unprognostic (8.55e-2)" "unprognostic (1.39e-1)" "unprognostic (4.51e-1)" "unprognostic (2.05e-2)" "unprognostic (2.61e-1)" "unprognostic (3.05e-2)" "unprognostic (2.29e-2)" "unprognostic (1.26e-1)" "unprognostic (1.48e-2)" "unprognostic (2.21e-1)" "unprognostic (2.76e-2)" "unprognostic (6.76e-2)" IRX4 ENSG00000113430 "Iroquois homeobox 4" P78413 5 1877413-1887236 "Plasma proteins, Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 14.2;heart muscle: 12.7;skin 1: 20.1;vagina: 11.0" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 56.0;Breast myoepithelial cells: 45.6;Cardiomyocytes: 45.1;Esophageal basal cells: 32.1;Migrating cytotrophoblasts: 13.1;Prostatic glandular cells: 10.2;Salivary basal cells: 21.0;Salivary myoepithelial cells: 15.2;Submucosal glandular cells: 22.2;Suprabasal keratinocytes: 17.6" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 8.4;Head and Neck Squamous Cell Carcinoma (TCGA): 10.9;Lung Squamous Cell Carcinoma (TCGA): 5.2;Prostate Adenocarcinoma (TCGA): 10.1;Testicular Germ Cell Tumor (TCGA): 10.9" "Group enriched" "Detected in some" 4 "cerebellum: 1.6;medulla oblongata: 1.8;midbrain: 1.6;pons: 2.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 10.6;Esophageal cancer: 7.0;head and neck cancer: 9.7" "Heart muscle - Cardiomyocytes, Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Prostate glandular cells" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "medulla oblongata: 1.4;pons: 1.6" HPA064094 Uncertain Nucleoplasm,Vesicles NA NA "Cluster 58: Skin - Keratinization" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 26: Keratinocytes - Keratinization" 3 "Nucleoplasm, Vesicles" "HPA064094: " "unprognostic (3.05e-3)" "unprognostic (3.99e-2)" "unprognostic (1.28e-1)" "unprognostic (1.36e-1)" "unprognostic (3.59e-1)" "unprognostic (1.15e-1)" "unprognostic (9.77e-2)" "unprognostic (1.17e-1)" "unprognostic (4.65e-1)" IRX5 IRX-2a ENSG00000176842 "Iroquois homeobox 5" P78411 16 54930865-54934485 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Sensory transduction, Transcription, Vision" DNA-binding "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 13.2;skin 1: 16.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 39.4;Basal prostatic cells: 44.5;Breast hormone-responsive cells: 50.4;Breast lactating cells: 90.2;Breast myoepithelial cells: 92.1;Breast secretory cells: 36.8;Melanocytes: 36.0;Müller glia: 46.9;Respiratory basal cells: 33.7;Respiratory ciliated cells: 35.2;Respiratory deuterosomal cells: 32.1;Respiratory ionocytes: 35.6;Respiratory secretory cells: 34.7" "Cell type enhanced" "Detected in some" "astrocyte: 9.4;Bergmann glia: 26.8;ependymal cell: 13.7" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 39.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "breast cancer: 21.0" "Breast - Breast glandular cells, Breast - Breast glandular cells, Lung - Alveolar cells type 2, Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA047130 Approved "Nuclear speckles,Microtubules,Cytosol" No NA "Cluster 58: Skin - Keratinization" "Cluster 44: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 4: Breast lactating luminal cells - Lactation" "Nuclear speckles" "Microtubules, Cytosol" "HPA047130: " "unprognostic (1.89e-1)" "unprognostic (1.81e-1)" "unprognostic (2.12e-2)" "unprognostic (2.55e-1)" "unprognostic (9.18e-2)" "unprognostic (3.18e-2)" "unprognostic (1.55e-2)" "unprognostic (1.59e-2)" "unprognostic (4.44e-3)" "unprognostic (1.43e-1)" "potential prognostic favorable (6.49e-4)" "potential prognostic favorable (1.12e-7)" "unprognostic (1.59e-1)" "unprognostic (1.29e-1)" "unprognostic (1.76e-1)" "unprognostic (1.40e-1)" "unprognostic (1.12e-1)" "unprognostic (6.33e-2)" "unprognostic (4.85e-2)" "unprognostic (1.50e-1)" "unprognostic (2.86e-1)" "unprognostic (1.39e-1)" "unprognostic (1.05e-1)" "unprognostic (2.16e-2)" "unprognostic (1.48e-1)" "unprognostic (1.51e-1)" IRX6 "IRX-3, IRX7" ENSG00000159387 "Iroquois homeobox 6" P78412 16 55324203-55330756 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 9.2;heart muscle: 10.8;skin 1: 9.8" "Cell type enhanced" "Detected in some" "Adipocytes: 16.0;Alveolar cells type 2: 8.5;Cardiomyocytes: 34.6;Epicardial cells: 4.5;Hofbauer cells: 12.7;Late spermatids: 12.2;Ocular epithelial cells: 4.2;Retinal bipolar cells: 11.9" "Cell type enhanced" "Detected in some" "medium spiny neuron: 1.4" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 11.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 3.2;skin cancer: 4.3;thyroid cancer: 5.1" "Pituitary gland - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA018332 Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 58: Skin - Keratinization" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 9 "Nucleoplasm, Mitochondria" "HPA018332: " "unprognostic (2.58e-3)" "unprognostic (9.80e-3)" "unprognostic (9.17e-2)" "unprognostic (9.38e-2)" "unprognostic (2.73e-3)" "unprognostic (5.79e-2)" "unprognostic (2.01e-2)" "potential prognostic favorable (5.29e-4)" "unprognostic (1.95e-1)" "unprognostic (8.88e-2)" "unprognostic (7.49e-2)" "unprognostic (2.22e-3)" "unprognostic (5.70e-2)" "unprognostic (1.03e-1)" ISCA1 "HBLD2, hIscA, ISA1, MGC4276" ENSG00000135070 "Iron-sulfur cluster assembly 1" Q9BUE6 9 86264546-86283102 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 896.4;Late primary spermatocytes: 321.5;Late spermatids: 770.4;Megakaryocytes: 408.0;Platelets: 307.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042789 Uncertain NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 1: Neurons - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 7 "HPA042789: " "unprognostic (6.06e-3)" "unprognostic (1.47e-1)" "unprognostic (2.86e-1)" "unprognostic (2.25e-1)" "unprognostic (2.63e-1)" "unprognostic (2.81e-2)" "unprognostic (1.02e-1)" "unprognostic (2.48e-3)" "unprognostic (4.73e-3)" "unprognostic (1.44e-1)" "validated prognostic favorable (7.73e-9)" "validated prognostic favorable (6.15e-4)" "unprognostic (1.73e-2)" "potential prognostic unfavorable (3.99e-4)" "unprognostic (2.35e-2)" "unprognostic (3.98e-1)" "unprognostic (2.15e-1)" "unprognostic (5.48e-2)" "unprognostic (9.72e-2)" "unprognostic (1.37e-1)" "unprognostic (2.24e-1)" "unprognostic (1.12e-1)" "unprognostic (1.19e-1)" "unprognostic (3.27e-1)" "potential prognostic favorable (8.27e-4)" "unprognostic (3.34e-2)" "unprognostic (6.13e-2)" "unprognostic (9.65e-2)" "unprognostic (1.84e-1)" "unprognostic (7.17e-3)" "unprognostic (1.43e-2)" ISCA2 "HBLD1, ISA2" ENSG00000165898 "Iron-sulfur cluster assembly 2" Q86U28 14 74493756-74497106 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 176.2;Parietal cells: 123.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030492 Approved NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 37 "HPA030492: " "unprognostic (1.33e-1)" "unprognostic (5.16e-2)" "unprognostic (2.19e-1)" "unprognostic (9.74e-2)" "unprognostic (1.19e-1)" "unprognostic (1.45e-1)" "unprognostic (3.85e-1)" "unprognostic (2.62e-2)" "unprognostic (3.94e-3)" "unprognostic (1.27e-1)" "potential prognostic favorable (3.94e-6)" "unprognostic (2.67e-2)" "unprognostic (1.21e-1)" "unprognostic (7.20e-3)" "unprognostic (1.31e-2)" "unprognostic (5.65e-2)" "unprognostic (3.82e-1)" "unprognostic (1.65e-2)" "unprognostic (4.37e-1)" "unprognostic (9.94e-2)" "unprognostic (1.73e-2)" "unprognostic (1.54e-1)" "unprognostic (3.33e-2)" "unprognostic (2.90e-1)" "unprognostic (5.62e-2)" "unprognostic (7.42e-3)" "unprognostic (1.36e-1)" "unprognostic (2.60e-2)" "unprognostic (3.63e-1)" "potential prognostic favorable (2.77e-4)" "unprognostic (3.05e-1)" ISCU "hnifU, ISU2, NIFUN" ENSG00000136003 "Iron-sulfur cluster assembly enzyme" Q9H1K1 12 108562582-108569368 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 558.0;Late spermatids: 1565.2;Parietal cells: 625.8;Syncytiotrophoblasts: 563.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "CAB006329, HPA038602, HPA057592" Approved Supported Mitochondria,Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 52: Non-specific - Cellular respiration" "Cluster 1: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 28 "Mitochondria, Cytosol" "CAB006329: , HPA038602: , HPA057592: " "unprognostic (1.08e-3)" "unprognostic (1.20e-1)" "unprognostic (1.34e-2)" "unprognostic (2.59e-3)" "unprognostic (1.20e-1)" "unprognostic (1.73e-2)" "unprognostic (3.78e-2)" "unprognostic (1.75e-2)" "unprognostic (1.41e-1)" "unprognostic (1.28e-1)" "potential prognostic favorable (1.70e-4)" "unprognostic (4.66e-3)" "unprognostic (1.12e-2)" "unprognostic (1.42e-1)" "unprognostic (1.89e-1)" "unprognostic (7.36e-2)" "unprognostic (5.02e-3)" "unprognostic (2.16e-1)" "unprognostic (1.62e-1)" "unprognostic (2.34e-1)" "unprognostic (2.56e-2)" "unprognostic (1.35e-3)" "unprognostic (1.56e-1)" "unprognostic (2.70e-3)" "unprognostic (2.21e-1)" "unprognostic (1.54e-3)" "unprognostic (2.11e-2)" "unprognostic (6.02e-2)" "unprognostic (1.11e-1)" "unprognostic (2.14e-2)" "unprognostic (1.72e-1)" ISG15 "G1P2, IFI15, UCRP" ENSG00000187608 "ISG15 ubiquitin like modifier" P05161 1 1001138-1014540 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 301.0" "Cell type enhanced" "Detected in many" "Colonocytes: 204.8;Decidual stromal cells: 231.4;Enterocytes: 459.0;Epididymal efferent duct ciliated cells: 236.3;Esophageal apical cells: 207.4;Extravillous trophoblasts: 787.8;Gastric progenitor cells: 374.2;Hofbauer cells: 357.6" "Cell type enhanced" "Detected in many" "endothelial cell: 100.3;pericyte: 86.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004627 Approved "Secreted to blood" Immunity NA NA 5000000 480000 "Cluster 19: Eosinophils - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 84 "HPA004627: " "unprognostic (1.86e-1)" "unprognostic (2.44e-1)" "unprognostic (2.07e-1)" "unprognostic (2.58e-2)" "unprognostic (7.11e-3)" "unprognostic (4.56e-2)" "unprognostic (9.77e-3)" "unprognostic (2.40e-1)" "unprognostic (8.17e-2)" "unprognostic (1.13e-1)" "validated prognostic unfavorable (7.44e-6)" "validated prognostic unfavorable (4.47e-4)" "unprognostic (3.38e-2)" "unprognostic (4.46e-3)" "unprognostic (1.84e-1)" "unprognostic (3.95e-2)" "unprognostic (2.64e-2)" "unprognostic (2.57e-1)" "unprognostic (3.85e-2)" "unprognostic (7.24e-2)" "unprognostic (1.41e-2)" "unprognostic (2.39e-3)" "unprognostic (5.53e-2)" "unprognostic (2.35e-1)" "unprognostic (1.49e-1)" "unprognostic (2.39e-3)" "unprognostic (1.05e-2)" "unprognostic (5.78e-2)" "unprognostic (2.95e-2)" "unprognostic (4.71e-2)" "unprognostic (1.24e-1)" ISG20 "CD25, HEM45" ENSG00000172183 "Interferon stimulated exonuclease gene 20" Q96AZ6 15 88635670-88656483 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity, rRNA processing" "Exonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 176.6" "Cell type enhanced" "Detected in many" "B-cells: 321.2;Endometrial ciliated cells: 323.1;Endometrial glandular cells: 300.6;Endometrial luminal cells: 298.4;Esophageal apical cells: 725.1;Neutrophils: 262.2;NK-cells: 306.0;Plasma cells: 1104.9;T-cells: 317.9" "Group enriched" "Detected in many" 6 "endothelial cell: 23.6;leukocyte: 68.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "lymphoma: 126.4;Myeloma: 113.2" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Not detected" "Not detected" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 18: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 44: Plasma cells - Antibody production & secretion" "unprognostic (1.47e-1)" "unprognostic (3.69e-2)" "unprognostic (3.21e-1)" "unprognostic (1.14e-2)" "unprognostic (3.45e-1)" "unprognostic (2.98e-1)" "potential prognostic unfavorable (5.42e-4)" "unprognostic (2.61e-2)" "unprognostic (5.78e-3)" "unprognostic (1.22e-1)" "potential prognostic unfavorable (3.62e-4)" "unprognostic (4.94e-2)" "unprognostic (2.03e-3)" "unprognostic (7.25e-2)" "unprognostic (3.18e-1)" "unprognostic (2.29e-3)" "unprognostic (2.94e-1)" "unprognostic (1.66e-1)" "unprognostic (8.06e-2)" "potential prognostic favorable (1.16e-4)" "unprognostic (2.52e-2)" "unprognostic (5.63e-3)" "unprognostic (1.52e-1)" "unprognostic (1.25e-1)" "unprognostic (1.05e-1)" "unprognostic (4.71e-2)" "potential prognostic favorable (3.31e-4)" "unprognostic (9.99e-2)" "unprognostic (5.09e-2)" "unprognostic (1.29e-1)" "unprognostic (2.11e-1)" ISG20L2 FLJ12671 ENSG00000143319 "Interferon stimulated exonuclease gene 20 like 2" Q9H9L3 1 156721891-156728766 "Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 58.8" "Cell type enriched" "Detected in many" 5 "Late spermatids: 5172.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028005, HPA054285" Approved Approved Nucleoplasm NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 39: Testis - Nuclear processes" "Cluster 15: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 7 Nucleoplasm "HPA028005: , HPA054285: " "unprognostic (3.95e-2)" "unprognostic (4.79e-2)" "unprognostic (9.00e-2)" "unprognostic (1.08e-2)" "unprognostic (2.76e-1)" "unprognostic (1.32e-1)" "unprognostic (1.88e-1)" "unprognostic (2.38e-2)" "unprognostic (2.23e-2)" "unprognostic (3.97e-2)" "unprognostic (2.05e-3)" "unprognostic (2.69e-2)" "unprognostic (8.88e-2)" "potential prognostic unfavorable (4.47e-5)" "unprognostic (4.11e-2)" "unprognostic (1.68e-2)" "unprognostic (3.22e-3)" "unprognostic (1.34e-3)" "unprognostic (5.70e-2)" "unprognostic (2.44e-1)" "unprognostic (8.28e-3)" "unprognostic (5.98e-2)" "unprognostic (1.39e-1)" "unprognostic (1.22e-1)" "unprognostic (1.47e-1)" "unprognostic (4.58e-2)" "unprognostic (2.02e-1)" "unprognostic (1.01e-1)" "unprognostic (2.23e-1)" "unprognostic (1.32e-3)" "unprognostic (2.77e-1)" ISL1 "Isl-1, ISLET1" ENSG00000016082 "ISL LIM homeobox 1" P61371 5 51383448-51394730 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 21.2;seminal vesicle: 18.1;vagina: 15.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 57.0;Medullary thymic epithelial cells: 43.2;Neuroendocrine cells: 62.5;Other brain neurons: 41.1;Pancreatic islet cells: 194.0;Retinal bipolar cells: 226.3;Retinal ganglion cells: 34.8;Retinal horizontal cells: 60.1;Syncytiotrophoblasts: 40.6;Thymic myoid cells: 40.8" "Group enriched" "Detected in some" 37 "medium spiny neuron: 20.2;splatter: 5.8" "Cancer enhanced" "Detected in some" "Pancreatic Adenocarcinoma (TCGA): 6.9" "Region enriched" "Detected in many" 6 "hypothalamus: 24.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 7 "Neuroblastoma: 93.2" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Pancreas - Alpha cells, Pituitary gland - Thyrotropes, Testis - Spermatogonia" "Group enriched" "Detected in many" 8 "basal ganglia: 13.8;hypothalamus: 15.0;thalamus: 6.0" "Group enriched" "Detected in some" 9 "basal ganglia: 7.7;hypothalamus: 7.1" "HPA048613, HPA057416" Approved Approved "Nucleoplasm,Nuclear speckles,Mitochondria" NA NA "Cluster 42: Retina - Visual perception" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 16 Nucleoplasm "Nuclear speckles, Mitochondria" "HPA048613: , HPA057416: " "unprognostic (9.67e-2)" "unprognostic (1.34e-2)" "unprognostic (1.70e-2)" "unprognostic (4.50e-3)" "unprognostic (2.56e-1)" "unprognostic (1.74e-1)" "unprognostic (2.72e-2)" "unprognostic (1.32e-1)" "unprognostic (1.54e-1)" ISL2 FLJ10160 ENSG00000159556 "ISL LIM homeobox 2" Q96A47 15 76336773-76342475 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 2.5;pituitary gland: 2.6;prostate: 2.3;vagina: 3.4" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 6.2;Basal prostatic cells: 4.2;Cone photoreceptor cells: 16.6;Oocytes: 4.6;Pituitary stem cells: 14.8;Plasma cells: 4.7;Prostatic club cells: 7.5;Prostatic hillock cells: 6.0;Salivary basal cells: 2.9;Salivary myoepithelial cells: 3.6;Thyrotrophs: 4.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "neutrophil: 9.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Breast - Plasma cells, Pituitary gland - Thyrotropes, Stomach - Fibroblasts" "Not detected" "Not detected" "Region enriched" "Detected in single" 10 "spinal cord: 2.4" HPA075192 Approved "Rods & Rings" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 1: Neuronal - Visual perception" "Cluster 67: Plasma cells - Plasma cell differentiation" 15 "Rods & Rings" "HPA075192: " "unprognostic (1.44e-1)" "unprognostic (1.42e-2)" "unprognostic (6.55e-2)" "unprognostic (1.63e-1)" "unprognostic (2.22e-2)" "unprognostic (2.43e-1)" "unprognostic (2.93e-1)" ISLR HsT17563 ENSG00000129009 "Immunoglobulin superfamily containing leucine rich repeat" O14498 15 74173710-74176872 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 214.1" "Cell type enriched" "Detected in some" 9 "Fibroblasts: 14.2" "Cell type enriched" "Detected in some" 10 "fibroblast: 355.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 30.9" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Fibroblasts, Breast - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Minor Salivary Gland - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblasts_2, Spleen - Fibroblasts_1, Spleen - Fibroblasts_2, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Region enriched" "Detected in all" 5 "olfactory bulb: 118.0" "Region enriched" "Detected in all" 5 "spinal cord: 164.5" "HPA040326, HPA050811" Approved Approved "Golgi apparatus,Plasma membrane" "Secreted - unknown location" "No annotated function" NA NA 27000000 "Cluster 75: Ovary - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 22: Non-specific - Basic cellular functions" 65 "Plasma membrane" "Golgi apparatus" "HPA040326: , HPA050811: " "unprognostic (1.19e-2)" "unprognostic (1.17e-1)" "unprognostic (2.70e-1)" "unprognostic (3.01e-1)" "unprognostic (2.11e-3)" "unprognostic (2.45e-1)" "unprognostic (3.62e-2)" "unprognostic (2.42e-2)" "unprognostic (8.32e-2)" "unprognostic (4.73e-2)" "unprognostic (1.31e-2)" "unprognostic (2.48e-1)" "potential prognostic unfavorable (1.00e-4)" "unprognostic (1.37e-1)" "unprognostic (4.53e-2)" "unprognostic (9.86e-2)" "unprognostic (1.25e-2)" "unprognostic (2.02e-1)" "unprognostic (2.13e-1)" "unprognostic (5.41e-3)" "unprognostic (8.59e-3)" "unprognostic (6.83e-2)" "unprognostic (1.68e-2)" "unprognostic (5.14e-2)" "unprognostic (1.22e-1)" "unprognostic (1.25e-3)" "unprognostic (2.63e-2)" "unprognostic (1.04e-2)" "unprognostic (8.65e-2)" "unprognostic (1.06e-1)" "unprognostic (3.37e-1)" ISLR2 KIAA1465 ENSG00000167178 "Immunoglobulin superfamily containing leucine rich repeat 2" Q6UXK2 15 74100311-74138540 "Predicted intracellular proteins, Predicted membrane proteins" Neurogenesis "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 15.5;heart muscle: 4.4;testis: 12.3" "Group enriched" "Detected in some" 9 "Early spermatids: 121.7;Late spermatids: 180.4" "Cell type enhanced" "Detected in many" "fibroblast: 35.4" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 6.8" "Region enhanced" "Detected in all" "cerebral cortex: 87.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "Neuroblastoma: 44.6;thyroid cancer: 16.4" "Minor Salivary Gland - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA012930, HPA067333" Uncertain NA NA 12000 "Cluster 73: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 6 "HPA012930: , HPA067333: " "unprognostic (6.00e-2)" "unprognostic (2.52e-2)" "unprognostic (2.69e-3)" "unprognostic (2.90e-2)" "unprognostic (6.06e-3)" "unprognostic (6.37e-2)" "unprognostic (1.28e-3)" "unprognostic (1.33e-1)" "unprognostic (1.17e-2)" "unprognostic (3.39e-1)" "unprognostic (8.75e-2)" "unprognostic (2.81e-1)" "unprognostic (1.30e-1)" "unprognostic (3.35e-2)" "unprognostic (1.19e-1)" "unprognostic (2.47e-2)" "unprognostic (1.37e-3)" "unprognostic (1.33e-2)" "unprognostic (1.81e-1)" "unprognostic (2.57e-1)" ISM1 "bA149I18.1, C20orf82" ENSG00000101230 "Isthmin 1" B1AKI9 20 13221274-13300651 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 22.6;thyroid gland: 34.9" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 160.2;Early spermatids: 29.8;Epicardial cells: 43.2;Fibro-adipogenic progenitors: 74.8;Fibroblasts: 93.0;Late primary spermatocytes: 42.6;Medullary thymic epithelial cells: 38.4;Pituitary stem cells: 55.0;Salivary myoepithelial cells: 44.3" "Cell type enriched" "Detected in many" 4 "fibroblast: 293.6" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 19.2" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "memory CD4 T-cell: 1.1" "Lineage enriched" "Detected in single" 11 "T-cells: 1.1" "Cancer enhanced" "Detected in many" "Kidney cancer: 4.8" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "hippocampal formation: 18.7" "Secreted in other tissues" "No annotated function" NA NA 17000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 38: Sub-cortical - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 108: Fibroblasts - ECM organization" "unprognostic (9.70e-2)" "unprognostic (2.11e-1)" "unprognostic (2.03e-1)" "unprognostic (5.18e-2)" "potential prognostic unfavorable (4.94e-4)" "unprognostic (3.21e-1)" "unprognostic (1.98e-1)" "unprognostic (5.59e-2)" "unprognostic (1.14e-3)" "unprognostic (1.60e-2)" "potential prognostic unfavorable (9.83e-4)" "unprognostic (1.83e-1)" "unprognostic (2.52e-2)" "unprognostic (2.18e-1)" "unprognostic (2.48e-3)" "unprognostic (4.07e-2)" "unprognostic (1.25e-1)" "unprognostic (1.49e-1)" "potential prognostic unfavorable (5.92e-4)" "unprognostic (4.30e-2)" "unprognostic (2.19e-1)" "unprognostic (2.16e-1)" "unprognostic (2.48e-2)" "unprognostic (2.13e-1)" "unprognostic (6.87e-3)" "unprognostic (5.11e-2)" "unprognostic (1.16e-1)" ISM2 "FLJ32147, TAIL1, THSD3" ENSG00000100593 "Isthmin 2" Q6H9L7 14 77474394-77498816 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 57 "placenta: 200.6" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 334.1;Extravillous trophoblasts: 1122.8;Migrating cytotrophoblasts: 494.0;Syncytiotrophoblasts: 192.9" "Group enriched" "Detected in some" 4 "eccentric medium spiny neuron: 10.0;medium spiny neuron: 6.9" "Cancer enhanced" "Detected in some" "Kidney Chromophobe (TCGA): 7.2" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 3.7" "Adipose visceral - Mesothelial cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells" "Not detected" "Not detected" "HPA039314, HPA039742" Supported Approved Nucleoplasm,Centrosome,Cytosol "Secreted in female reproductive system" "No annotated function" NA NA 900000 "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 34: Testis cancer - Unknown function" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 1 Nucleoplasm "Centrosome, Cytosol" "HPA039314: , HPA039742: " "unprognostic (9.45e-3)" "unprognostic (3.63e-3)" "potential prognostic favorable (7.13e-5)" "unprognostic (9.07e-2)" "unprognostic (1.79e-1)" "unprognostic (2.97e-1)" ISOC1 CGI-111 ENSG00000066583 "Isochorismatase domain containing 1" Q96CN7 5 129094749-129114028 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 119.4;Hepatocytes: 109.3;Oocytes: 124.3;Parietal cells: 123.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070307 Approved "Endoplasmic reticulum,Vesicles" NA NA 1500000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 27: Breast cancer - Unknown function" "Cluster 26: Keratinocytes - Keratinization" 3 "Endoplasmic reticulum, Vesicles" "HPA070307: " "unprognostic (8.15e-3)" "unprognostic (1.22e-1)" "unprognostic (2.43e-3)" "unprognostic (8.00e-2)" "unprognostic (9.49e-2)" "unprognostic (9.46e-3)" "unprognostic (1.32e-2)" "unprognostic (2.68e-1)" "unprognostic (1.05e-1)" "unprognostic (2.17e-3)" "potential prognostic favorable (1.14e-6)" "unprognostic (4.53e-2)" "unprognostic (1.25e-2)" "unprognostic (6.85e-2)" "unprognostic (3.95e-2)" "unprognostic (9.51e-2)" "unprognostic (3.35e-1)" "unprognostic (2.35e-1)" "unprognostic (5.06e-2)" "unprognostic (2.21e-1)" "unprognostic (4.92e-2)" "unprognostic (1.12e-1)" "unprognostic (2.16e-1)" "unprognostic (1.43e-1)" "unprognostic (1.44e-1)" "unprognostic (9.30e-2)" "unprognostic (1.69e-1)" "unprognostic (7.64e-2)" "unprognostic (2.32e-1)" "unprognostic (6.18e-2)" "unprognostic (1.57e-1)" ISOC2 FLJ23469 ENSG00000063241 "Isochorismatase domain containing 2" Q96AB3 19 55452985-55462343 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 262.8" "Cell type enhanced" "Detected in many" "Enterocytes: 231.4;Esophageal basal cells: 200.2;Hepatocytes: 322.3;Late primary spermatocytes: 316.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043142 Enhanced Approved Mitochondria,Cytosol NA NA 130000 "Cluster 13: Non-specific - Mitochondria" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 4: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 1 Mitochondria Cytosol "HPA043142: " "unprognostic (1.03e-1)" "unprognostic (4.51e-2)" "unprognostic (8.75e-2)" "unprognostic (4.09e-3)" "unprognostic (1.95e-1)" "unprognostic (1.47e-1)" "unprognostic (2.67e-1)" "unprognostic (2.11e-1)" "unprognostic (1.04e-1)" "unprognostic (4.37e-2)" "potential prognostic favorable (4.40e-5)" "unprognostic (4.95e-1)" "unprognostic (3.03e-2)" "unprognostic (2.91e-1)" "unprognostic (1.25e-1)" "unprognostic (5.40e-3)" "unprognostic (6.09e-2)" "unprognostic (1.61e-1)" "unprognostic (2.39e-1)" "unprognostic (1.47e-1)" "unprognostic (8.58e-2)" "unprognostic (9.67e-3)" "unprognostic (2.92e-3)" "unprognostic (1.09e-2)" "unprognostic (5.30e-2)" "unprognostic (1.19e-1)" "unprognostic (1.08e-1)" "unprognostic (1.68e-1)" "unprognostic (1.35e-1)" "unprognostic (8.17e-2)" "unprognostic (1.94e-1)" IST1 "CHMP8, KIAA0174" ENSG00000182149 "IST1 factor associated with ESCRT-III" P53990 16 71845996-71931199 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 338.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041802, HPA054532" Approved Supported Vesicles NA NA 330000 "Cluster 35: Neutrophils - Protein binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 25 Vesicles "HPA041802: , HPA054532: " "unprognostic (1.92e-1)" "unprognostic (9.03e-2)" "unprognostic (1.13e-1)" "unprognostic (2.62e-1)" "unprognostic (2.42e-1)" "unprognostic (1.49e-1)" "unprognostic (1.22e-3)" "unprognostic (2.96e-2)" "unprognostic (9.79e-2)" "potential prognostic favorable (2.98e-8)" "unprognostic (5.94e-3)" "unprognostic (3.85e-2)" "unprognostic (2.31e-3)" "unprognostic (1.59e-1)" "unprognostic (2.47e-2)" "potential prognostic unfavorable (7.12e-4)" "unprognostic (9.41e-2)" "unprognostic (3.12e-2)" "unprognostic (1.04e-1)" "unprognostic (3.57e-2)" "unprognostic (1.04e-3)" "unprognostic (4.43e-2)" "unprognostic (4.81e-2)" "unprognostic (6.60e-3)" "unprognostic (1.04e-1)" "unprognostic (2.25e-1)" "unprognostic (1.79e-1)" "unprognostic (2.89e-1)" "unprognostic (1.17e-1)" ISX RAXLX ENSG00000175329 "Intestine specific homeobox" Q2M1V0 22 35066136-35087387 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 70 "intestine: 35.2" "Cell type enhanced" "Detected in some" "Colonocytes: 32.2;Enteric stem cells: 24.5;Enteric transient amplifying cells: 22.9;Enterocytes: 32.6;Goblet cells: 18.9;Neuroendocrine cells: 10.1;Paneth cells: 7.7;Podocytes: 14.7;Tuft cells: 11.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Colon Adenocarcinoma (TCGA): 8.5;Rectum Adenocarcinoma (TCGA): 11.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Bile duct cancer: 11.0;colorectal cancer: 4.8" "Colon - Colon enterocytes, Kidney - Podocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA060328 Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 77: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 12 Nucleoplasm "Nuclear bodies" "HPA060328: " "unprognostic (1.90e-1)" "unprognostic (6.58e-2)" "unprognostic (1.18e-1)" "unprognostic (2.10e-1)" "unprognostic (1.33e-1)" "unprognostic (1.73e-1)" "unprognostic (1.67e-3)" "unprognostic (2.07e-1)" ISY1 "fSAP33, KIAA1160" ENSG00000240682 "ISY1 splicing factor homolog" Q9ULR0 3 129127415-129161063 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 10.2;Bergmann glia: 11.5;Brain excitatory neurons: 15.0;Brain inhibitory neurons: 14.3;Choroid plexus epithelial cells: 17.0;Ependymal cells: 9.7;Microglia: 14.1;Oligodendrocyte progenitor cells: 10.6;Oligodendrocytes: 14.2;Other brain neurons: 12.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006312, HPA016995" Supported Enhanced "Nuclear speckles" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 15: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 22: Non-specific - Basic cellular functions" 38 "Nuclear speckles" "HPA006312: , HPA016995: " "unprognostic (2.52e-1)" "unprognostic (1.30e-1)" "unprognostic (2.74e-1)" "unprognostic (6.93e-2)" "unprognostic (4.08e-2)" "unprognostic (6.38e-2)" "unprognostic (5.01e-2)" "unprognostic (1.28e-3)" "unprognostic (1.40e-1)" "potential prognostic unfavorable (2.25e-4)" "potential prognostic favorable (3.38e-4)" "unprognostic (5.88e-2)" "unprognostic (8.32e-2)" "validated prognostic unfavorable (3.20e-5)" "validated prognostic unfavorable (2.41e-5)" "unprognostic (2.39e-2)" "unprognostic (3.92e-3)" "unprognostic (3.55e-2)" "unprognostic (3.58e-1)" "unprognostic (4.18e-2)" "unprognostic (7.75e-2)" "unprognostic (1.19e-3)" "unprognostic (7.80e-3)" "unprognostic (2.01e-1)" "unprognostic (3.36e-3)" "unprognostic (6.27e-2)" "unprognostic (1.43e-1)" "unprognostic (7.34e-3)" "unprognostic (1.65e-1)" "unprognostic (5.24e-2)" "unprognostic (3.48e-1)" ISY1-RAB43 ENSG00000261796 "ISY1-RAB43 readthrough" 3 129087575-129161036 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cholangiocytes: 3.9;Cone photoreceptor cells: 6.2;Neutrophils: 4.2;Retinal ganglion cells: 7.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "HPA006312, HPA016995" Approved Enhanced "Nuclear speckles" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 49: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 20: Non-specific - Transcription regulation" 2 "Nuclear speckles" "HPA006312: , HPA016995: " "unprognostic (6.41e-2)" "unprognostic (6.91e-2)" "unprognostic (6.73e-2)" "unprognostic (9.37e-3)" "unprognostic (1.78e-1)" "unprognostic (2.80e-1)" "unprognostic (3.59e-2)" "unprognostic (7.48e-2)" "potential prognostic favorable (1.30e-6)" "unprognostic (1.07e-1)" "unprognostic (3.11e-1)" "potential prognostic unfavorable (6.86e-4)" "unprognostic (1.44e-1)" "unprognostic (1.50e-1)" "unprognostic (8.87e-2)" "unprognostic (1.64e-1)" "unprognostic (1.12e-3)" "unprognostic (3.35e-2)" "unprognostic (3.07e-2)" "unprognostic (4.59e-1)" "unprognostic (2.76e-2)" "unprognostic (8.54e-2)" "unprognostic (5.89e-2)" "unprognostic (5.56e-1)" "unprognostic (1.95e-2)" "unprognostic (3.02e-1)" "unprognostic (2.40e-1)" "unprognostic (3.55e-1)" ISYNA1 "Ino1, INOS, IPS" ENSG00000105655 "Inositol-3-phosphate synthase 1" Q9NPH2 19 18434388-18438167 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Inositol biosynthesis, Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 199.7;testis: 219.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1351.8;Fallopian secretory cells: 345.4;Granulosa cells: 648.8;Late spermatids: 381.6;Migrating cytotrophoblasts: 793.1;Sertoli cells: 299.1;Syncytiotrophoblasts: 1148.8" "Group enriched" "Detected in all" 7 "choroid plexus epithelial cell: 189.4;pericyte: 385.1;vascular associated smooth muscle cell: 179.2" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 11 "choroid plexus: 465.5" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 4.5;NK-cells: 14.5;T-cells: 9.0" "Cancer enhanced" "Detected in all" "Rhabdoid: 252.6" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007931, HPA008232, CAB020720" Enhanced Approved Nucleoplasm,Cytosol NA NA 7300 "Cluster 27: T-cells - Unknown function" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 6 Nucleoplasm Cytosol "CAB020720: , HPA007931: , HPA008232: " "unprognostic (3.44e-2)" "unprognostic (1.02e-1)" "unprognostic (4.67e-1)" "unprognostic (1.10e-1)" "unprognostic (1.48e-2)" "unprognostic (4.61e-2)" "unprognostic (1.97e-1)" "unprognostic (6.90e-2)" "unprognostic (2.36e-2)" "unprognostic (1.87e-1)" "unprognostic (4.88e-3)" "unprognostic (4.57e-2)" "unprognostic (4.01e-2)" "unprognostic (1.03e-1)" "unprognostic (1.59e-1)" "unprognostic (3.36e-3)" "unprognostic (1.76e-1)" "unprognostic (1.94e-1)" "unprognostic (4.56e-2)" "unprognostic (9.08e-2)" "unprognostic (5.50e-3)" "unprognostic (2.98e-2)" "unprognostic (4.55e-3)" "unprognostic (2.56e-1)" "unprognostic (5.16e-2)" "unprognostic (1.45e-2)" "unprognostic (1.66e-1)" "unprognostic (9.65e-3)" "unprognostic (2.78e-1)" "unprognostic (3.10e-2)" "unprognostic (2.95e-1)" ITCH AIP4 ENSG00000078747 "Itchy E3 ubiquitin protein ligase" Q96J02 20 34363235-34511773 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Antiviral defense, Apoptosis, Host-virus interaction, Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 103.4;Bergmann glia: 133.0;Brain excitatory neurons: 107.4;Brain inhibitory neurons: 100.6;Choroid plexus epithelial cells: 286.1;Distal convoluted tubule cells: 226.0;Ependymal cells: 107.5;Loop of henle epithelial cells: 180.7;Microglia: 187.9;Oligodendrocyte progenitor cells: 123.6;Oligodendrocytes: 360.6;Papillary tip epithelial cells: 207.9;Podocytes: 211.1;Proximal tubule cells: 258.0;Renal collecting duct intercalated cells: 194.8;Renal collecting duct principal cells: 188.9;Renal connecting tubule cells: 219.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021126, HPA049032, CAB072824, CAB072825" Supported Enhanced Nucleoplasm,Vesicles No No "Cluster 35: Neutrophils - Protein binding" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 11: White matter - Signal transduction" "Cluster 62: Non-specific - Plasma proteins" "Cluster 102: Non-specific - Mixed function" 141 Nucleoplasm Vesicles "CAB072824: , CAB072825: , HPA021126: , HPA049032: " "unprognostic (3.03e-1)" "unprognostic (1.28e-1)" "unprognostic (6.92e-2)" "unprognostic (1.37e-3)" "unprognostic (3.88e-2)" "unprognostic (3.76e-1)" "unprognostic (1.61e-1)" "unprognostic (3.01e-2)" "unprognostic (3.68e-1)" "unprognostic (1.23e-2)" "validated prognostic favorable (9.00e-6)" "validated prognostic favorable (8.48e-4)" "unprognostic (2.50e-1)" "unprognostic (1.02e-1)" "unprognostic (3.63e-1)" "unprognostic (2.98e-2)" "unprognostic (1.11e-3)" "potential prognostic unfavorable (1.69e-4)" "unprognostic (4.96e-1)" "unprognostic (1.57e-2)" "potential prognostic unfavorable (1.26e-5)" "unprognostic (3.11e-3)" "potential prognostic unfavorable (5.27e-7)" "unprognostic (4.85e-2)" "unprognostic (1.85e-3)" "unprognostic (1.24e-1)" "unprognostic (1.09e-1)" "unprognostic (6.54e-2)" "unprognostic (3.40e-1)" "unprognostic (7.67e-3)" "unprognostic (1.09e-1)" ITFG1 "CDA08, LNKN-1, TIP" ENSG00000129636 "Integrin alpha FG-GAP repeat containing 1" Q8TB96 16 47154387-47464149 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Sertoli cells: 1253.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015590, HPA019728, HPA019752" Approved Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" "No annotated function" NA NA 19000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 73: Brain - Neuronal signaling" "Cluster 23: Choroid plexus - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 37 "Golgi apparatus, Vesicles" "HPA015590: , HPA019728: , HPA019752: " "unprognostic (6.34e-2)" "unprognostic (1.71e-2)" "unprognostic (1.63e-1)" "unprognostic (5.51e-3)" "unprognostic (5.49e-2)" "unprognostic (2.91e-1)" "unprognostic (1.85e-1)" "unprognostic (2.86e-2)" "unprognostic (7.51e-2)" "unprognostic (1.80e-1)" "potential prognostic favorable (5.83e-7)" "unprognostic (8.75e-2)" "unprognostic (1.02e-1)" "unprognostic (2.87e-2)" "unprognostic (3.40e-1)" "unprognostic (2.12e-1)" "unprognostic (1.02e-1)" "unprognostic (3.89e-2)" "unprognostic (1.65e-2)" "unprognostic (4.45e-2)" "unprognostic (1.58e-2)" "unprognostic (1.08e-1)" "unprognostic (3.49e-1)" "unprognostic (1.68e-1)" "unprognostic (1.04e-1)" "unprognostic (3.64e-2)" "unprognostic (1.95e-2)" "unprognostic (6.77e-2)" "unprognostic (2.62e-1)" "unprognostic (4.89e-2)" "unprognostic (8.78e-2)" ITFG2 "FGGAP1, KICS3, MDS028" ENSG00000111203 "Integrin alpha FG-GAP repeat containing 2" Q969R8 12 2812622-2859791 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038664, HPA038665, HPA074606" Uncertain Supported "Golgi apparatus,Vesicles" NA No "Cluster 14: Non-specific - Unknown function" "Cluster 54: Non-specific - Ribosome" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 38: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 15 Vesicles "Golgi apparatus" "HPA038664: , HPA038665: , HPA074606: " "unprognostic (9.37e-2)" "unprognostic (4.50e-1)" "unprognostic (1.29e-1)" "unprognostic (1.59e-2)" "unprognostic (3.61e-3)" "unprognostic (9.78e-2)" "unprognostic (2.61e-2)" "unprognostic (1.94e-1)" "unprognostic (1.78e-1)" "unprognostic (8.48e-2)" "unprognostic (6.55e-3)" "potential prognostic favorable (1.08e-4)" "unprognostic (2.91e-1)" "unprognostic (1.44e-2)" "unprognostic (1.23e-1)" "unprognostic (9.44e-2)" "unprognostic (5.24e-2)" "unprognostic (1.51e-1)" "unprognostic (5.43e-2)" "unprognostic (2.23e-3)" "unprognostic (5.38e-2)" "unprognostic (4.15e-2)" "unprognostic (4.16e-2)" "unprognostic (1.77e-2)" "unprognostic (8.14e-2)" "unprognostic (4.47e-2)" "unprognostic (1.39e-3)" "unprognostic (7.46e-2)" "unprognostic (8.72e-2)" "unprognostic (9.42e-2)" "unprognostic (4.99e-2)" ITGA1 "CD49a, VLA1" ENSG00000213949 "Integrin subunit alpha 1" P56199 5 52787916-52959209 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Transporters" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 192.3;Adrenal cortex cells: 611.9;Hepatic stellate cells: 367.9;Hepatocytes: 214.2;Lymphatic endothelial cells: 351.0;Pericytes: 444.3;Podocytes: 287.8;Schwann cells: 153.4;Smooth muscle cells: 257.8;Vascular endothelial cells: 276.0;Vascular smooth muscle cells: 283.2" "Cell type enhanced" "Detected in all" "endothelial cell: 497.4;pericyte: 578.6;vascular associated smooth muscle cell: 396.9" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 4.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Heart muscle - Endothelial cells, Minor Salivary Gland - Endothelial cells, Pancreas - Endothelial cells, Prostate - Smooth muscle cells, Skeletal muscle - Endothelial cells, Spleen - Endothelial cells, Testis - Endothelial cells, Thyroid gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042555 Uncertain Approved "Endoplasmic reticulum" NA NA 2000000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 47: Endothelial cells - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 6 "Endoplasmic reticulum" "HPA042555: " "unprognostic (2.92e-2)" "unprognostic (1.55e-1)" "unprognostic (9.04e-2)" "potential prognostic favorable (1.59e-4)" "unprognostic (1.10e-3)" "unprognostic (3.46e-2)" "unprognostic (8.88e-2)" "unprognostic (1.01e-1)" "unprognostic (6.42e-3)" "unprognostic (2.13e-2)" "unprognostic (1.30e-3)" "unprognostic (6.03e-2)" "unprognostic (9.55e-2)" "unprognostic (2.68e-1)" "unprognostic (1.45e-1)" "unprognostic (4.49e-3)" "unprognostic (5.91e-2)" ITGA10 ENSG00000143127 "Integrin subunit alpha 10" O75578 1 145891208-145910111 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "blood vessel: 114.0" "Cell type enriched" "Detected in many" 6 "Thymic myoid cells: 444.6" "Cell type enhanced" "Detected in all" "fibroblast: 123.0;pericyte: 159.6" "Cancer enriched" "Detected in many" 4 "Skin Cutaneous Melanoma (TCGA): 12.4" "Region enriched" "Detected in all" 4 "choroid plexus: 15.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Bone cancer: 5.2;Rhabdoid: 20.0;skin cancer: 5.9" "Breast - Breast glandular cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA064008 Uncertain "Endoplasmic reticulum" NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" "Endoplasmic reticulum" "HPA064008: " "unprognostic (9.61e-3)" "unprognostic (3.65e-2)" "unprognostic (2.48e-1)" "unprognostic (3.31e-1)" "unprognostic (3.06e-2)" "unprognostic (1.21e-3)" "potential prognostic favorable (3.55e-4)" "unprognostic (2.30e-1)" "unprognostic (5.98e-2)" "unprognostic (2.79e-3)" "unprognostic (1.07e-1)" "unprognostic (8.06e-2)" "unprognostic (4.66e-1)" "unprognostic (1.83e-1)" "potential prognostic unfavorable (3.24e-4)" ITGA11 HsT18964 ENSG00000137809 "Integrin subunit alpha 11" Q9UKX5 15 68296532-68432163 "Predicted membrane proteins, Transporters" "Cell adhesion" "Integrin, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 74.1;endometrium 1: 28.8" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 68.8;Fibro-adipogenic progenitors: 272.9;Fibroblasts: 66.1;Hepatic stellate cells: 77.5;Leydig cells: 36.4;Pericytes: 35.7;Peritubular myoid cells: 52.5;Retinal amacrine cells: 89.8;Vascular smooth muscle cells: 29.7" "Cell type enriched" "Detected in many" 4 "fibroblast: 154.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 34.8" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Fibroblasts, Kidney - Fibroblasts, Minor Salivary Gland - Fibroblasts, Pituitary gland - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "basal ganglia: 9.8;spinal cord: 2.8" HPA051813 Uncertain NA NA 110000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 53: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" "HPA051813: " "unprognostic (1.38e-3)" "unprognostic (5.13e-2)" "unprognostic (1.18e-1)" "unprognostic (5.82e-2)" "unprognostic (2.24e-2)" "unprognostic (3.06e-1)" "unprognostic (6.87e-2)" "unprognostic (2.51e-1)" "unprognostic (3.87e-1)" "unprognostic (1.36e-1)" "unprognostic (9.65e-2)" "potential prognostic unfavorable (1.40e-4)" "unprognostic (5.69e-2)" "potential prognostic unfavorable (9.07e-4)" "unprognostic (3.79e-3)" "unprognostic (2.79e-2)" "unprognostic (1.18e-1)" "unprognostic (4.12e-2)" "potential prognostic unfavorable (2.04e-4)" "unprognostic (3.40e-2)" "unprognostic (3.59e-1)" "unprognostic (2.00e-1)" "unprognostic (1.51e-1)" "unprognostic (4.51e-3)" "unprognostic (6.05e-2)" "unprognostic (7.87e-3)" "unprognostic (1.51e-2)" "unprognostic (3.75e-2)" "unprognostic (6.10e-3)" ITGA2 CD49B ENSG00000164171 "Integrin subunit alpha 2" P17301 5 52989340-53094779 "Cancer-related genes, CD markers, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 493.8;Conjunctival goblet cells: 532.0;Epididymal basal cells: 1195.1;Ocular epithelial cells: 906.9;Pancreatic acinar cells: 663.6;Renal connecting tubule cells: 509.0;Respiratory basal cells: 406.9;Salivary basal cells: 470.7;Urothelial cells: 904.2" "Cell type enhanced" "Detected in many" "ependymal cell: 200.0;oligodendrocyte: 479.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast myoepithelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB017690, HPA060991, HPA063556" Enhanced NA No 8200000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 21 "CAB017690: , HPA060991: , HPA063556: " "unprognostic (3.05e-1)" "unprognostic (1.65e-1)" "unprognostic (2.09e-1)" "unprognostic (3.44e-2)" "unprognostic (2.02e-2)" "unprognostic (9.55e-2)" "unprognostic (4.04e-1)" "unprognostic (2.64e-3)" "unprognostic (5.49e-2)" "unprognostic (7.06e-2)" "potential prognostic favorable (6.41e-7)" "unprognostic (1.56e-3)" "unprognostic (1.04e-2)" "unprognostic (1.75e-3)" "unprognostic (1.10e-1)" "unprognostic (5.44e-2)" "unprognostic (1.27e-2)" "unprognostic (9.70e-2)" "unprognostic (7.90e-2)" "unprognostic (2.38e-2)" "unprognostic (1.85e-3)" "potential prognostic unfavorable (5.52e-5)" "unprognostic (1.08e-3)" "unprognostic (1.70e-1)" "unprognostic (1.03e-2)" "unprognostic (1.69e-2)" "unprognostic (4.63e-1)" "unprognostic (9.70e-2)" "unprognostic (1.24e-1)" "unprognostic (3.20e-1)" "unprognostic (1.44e-1)" ITGA2B "CD41, CD41B, GP2B, PPP1R93" ENSG00000005961 "Integrin subunit alpha 2b" P08514 17 44372180-44389649 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 15.7;epididymis: 10.1;lymphoid tissue: 11.7" "Cell type enriched" "Detected in many" 4 "Platelets: 3636.4" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 6.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 14 "basophil: 65.1" "Lineage enriched" "Detected in single" 75 "granulocytes: 65.1" "Cancer enriched" "Detected in some" 59 "Leukemia: 83.1" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB018611, HPA031168, HPA031169, HPA031170, HPA031171" Enhanced Approved "Plasma membrane" NA NA 150000000 "Cluster 41: Basophils - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 47: Platelets - Hemostasis" 8 "Plasma membrane" "CAB018611: , HPA031168: , HPA031169: , HPA031170: , HPA031171: " "unprognostic (2.44e-2)" "unprognostic (2.67e-1)" "unprognostic (1.27e-2)" "unprognostic (9.29e-3)" "unprognostic (5.64e-2)" "unprognostic (3.09e-1)" "unprognostic (1.49e-1)" "unprognostic (3.17e-1)" "unprognostic (1.52e-1)" ITGA3 "CD49c, GAP-B3, MSK18, VCA-2, VLA3a" ENSG00000005884 "Integrin subunit alpha 3" P26006 17 50055968-50090481 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes, Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 500.5;Papillary tip epithelial cells: 210.3;Podocytes: 417.1;Transitional alveolar cells: 168.5;Urothelial cells: 243.2" "Cell type enhanced" "Detected in many" "vascular associated smooth muscle cell: 121.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Breast myoepithelial cells, Kidney - Endothelial cells, Lung - Alveolar cells type 1, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008572, CAB018594" Enhanced Supported "Plasma membrane" NA NA 47000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 1: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 69: Urothelial cells - Basic cellular functions" 15 "Plasma membrane" "CAB018594: , HPA008572: " "unprognostic (7.22e-2)" "unprognostic (1.21e-1)" "unprognostic (2.78e-1)" "unprognostic (1.78e-2)" "unprognostic (5.74e-3)" "unprognostic (1.35e-1)" "unprognostic (4.84e-3)" "unprognostic (2.05e-3)" "potential prognostic unfavorable (1.60e-4)" "unprognostic (2.19e-1)" "potential prognostic favorable (6.07e-4)" "unprognostic (5.51e-2)" "unprognostic (7.36e-2)" "unprognostic (3.01e-2)" "unprognostic (3.32e-3)" "unprognostic (4.09e-2)" "unprognostic (8.18e-3)" "potential prognostic unfavorable (9.31e-5)" "unprognostic (3.58e-2)" "unprognostic (3.57e-2)" "unprognostic (2.72e-1)" "validated prognostic unfavorable (1.33e-4)" "validated prognostic unfavorable (2.27e-5)" "unprognostic (1.48e-2)" "unprognostic (2.27e-1)" "unprognostic (6.81e-2)" "potential prognostic favorable (8.80e-4)" "unprognostic (1.84e-1)" "unprognostic (2.48e-1)" "unprognostic (1.45e-1)" "unprognostic (2.40e-2)" ITGA4 CD49D ENSG00000115232 "Integrin subunit alpha 4" P13612 2 181457202-181538940 "Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 44.0;lymphoid tissue: 69.0" "Cell type enhanced" "Detected in many" "B-cells: 236.4;cDC: 184.0;Erythrocyte progenitors: 638.8;Hematopoietic stem cells: 454.2;Innate lymphoid cells: 255.3;Megakaryocyte progenitors: 238.2;Megakaryocyte-Erythroid progenitors: 675.4;monocytes: 192.0;Neutrophil progenitors: 189.2;NK-cells: 416.5;Oocytes: 211.8;Plasma cells: 166.9;T-cells: 336.8;Thymocytes: 491.2" "Cell type enriched" "Detected in many" 4 "leukocyte: 647.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 112.7;Myeloma: 80.8" "Adipose visceral - T-cells, Breast - T-cells, Prostate - T-cells, Thyroid gland - T-cells" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 7 "cerebellum: 18.6" HPA074961 Approved "Plasma membrane" "Intracellular and membrane" Receptor NA NA 140000 "Cluster 25: Non-specific - Unknown function" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 35: Non-specific - DNA binding" "Cluster 47: Leukemia - Hemostasis" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 10 "Plasma membrane" "HPA074961: " "unprognostic (2.03e-2)" "unprognostic (2.69e-1)" "unprognostic (7.94e-2)" "unprognostic (1.37e-2)" "unprognostic (1.03e-1)" "unprognostic (1.68e-1)" "unprognostic (2.59e-1)" "unprognostic (6.59e-2)" "unprognostic (1.37e-3)" "unprognostic (9.56e-2)" "potential prognostic favorable (7.59e-4)" "unprognostic (5.42e-2)" "unprognostic (3.01e-3)" "unprognostic (3.03e-1)" "unprognostic (4.21e-2)" "potential prognostic favorable (9.06e-4)" "unprognostic (5.85e-3)" "unprognostic (2.06e-2)" "unprognostic (7.26e-2)" "unprognostic (6.31e-2)" "unprognostic (1.17e-1)" "unprognostic (1.83e-1)" "unprognostic (1.30e-2)" "unprognostic (3.18e-1)" "unprognostic (7.23e-2)" "unprognostic (2.64e-2)" "unprognostic (1.48e-1)" "unprognostic (6.77e-2)" "unprognostic (3.33e-3)" "unprognostic (4.44e-2)" "unprognostic (3.18e-1)" ITGA5 "CD49e, FNRA" ENSG00000161638 "Integrin subunit alpha 5" P08648 12 54395261-54419266 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 733.7" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 116.0;Extravillous trophoblasts: 553.9;Fibroblasts: 98.7;Lymphatic endothelial cells: 96.9;monocytes: 164.2;Neutrophils: 104.0;Smooth muscle cells: 675.2;Vascular endothelial cells: 176.7" "Group enriched" "Detected in many" 5 "central nervous system macrophage: 54.2;endothelial cell: 76.7;fibroblast: 27.5;leukocyte: 37.8;vascular associated smooth muscle cell: 24.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 89.4" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Pituitary gland - Endothelial cells, Prostate - Smooth muscle cells, Testis - Endothelial cells" "Region enriched" "Detected in many" 5 "basal ganglia: 10.4" "Low region specificity" "Detected in many" "HPA002642, CAB009008" Enhanced NA NA 4000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 12: Non-specific - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 33 "CAB009008: , HPA002642: " "unprognostic (3.86e-1)" "unprognostic (7.37e-3)" "unprognostic (2.32e-1)" "potential prognostic unfavorable (4.44e-5)" "unprognostic (1.79e-2)" "unprognostic (2.58e-1)" "unprognostic (3.40e-3)" "unprognostic (5.39e-3)" "potential prognostic unfavorable (1.78e-4)" "unprognostic (7.83e-2)" "unprognostic (7.16e-2)" "unprognostic (3.37e-1)" "potential prognostic unfavorable (6.56e-4)" "potential prognostic unfavorable (5.01e-6)" "unprognostic (1.33e-1)" "unprognostic (2.03e-3)" "potential prognostic unfavorable (1.36e-5)" "unprognostic (7.09e-3)" "unprognostic (8.52e-2)" "unprognostic (7.14e-2)" "unprognostic (3.31e-2)" "unprognostic (2.40e-2)" "unprognostic (1.88e-2)" "unprognostic (1.31e-1)" "unprognostic (3.28e-2)" "unprognostic (1.26e-1)" "unprognostic (1.42e-2)" "potential prognostic unfavorable (9.34e-4)" "unprognostic (4.97e-2)" "unprognostic (4.54e-3)" "unprognostic (3.17e-1)" ITGA6 CD49f ENSG00000091409 "Integrin subunit alpha 6" P23229 2 172427354-172506459 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 685.9;Pancreatic acinar cells: 594.5;Paneth cells: 947.5;Renal collecting duct intercalated cells: 1667.9;Retinal pigment epithelial cells: 626.7;Salivary basal cells: 674.1;Urothelial cells: 789.5" "Cell type enriched" "Detected in many" 4 "endothelial cell: 920.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 22.5" "Group enriched" "Detected in many" 28 "granulocytes: 22.5;NK-cells: 7.3;T-cells: 12.5" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009009, HPA012696, HPA027582" Supported NA NA 3400000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 60: Stomach - Digestion" "Cluster 8: Immune cells - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 16 "CAB009009: , HPA012696: , HPA027582: " "unprognostic (8.51e-2)" "unprognostic (1.18e-1)" "unprognostic (3.93e-2)" "unprognostic (5.40e-2)" "unprognostic (6.89e-2)" "unprognostic (1.02e-1)" "unprognostic (1.03e-1)" "potential prognostic unfavorable (8.11e-4)" "unprognostic (9.86e-3)" "unprognostic (4.86e-2)" "validated prognostic favorable (3.55e-15)" "validated prognostic favorable (8.53e-4)" "unprognostic (1.36e-1)" "unprognostic (2.65e-2)" "unprognostic (5.70e-2)" "potential prognostic unfavorable (1.44e-5)" "unprognostic (6.88e-2)" "unprognostic (1.78e-1)" "unprognostic (2.23e-1)" "unprognostic (1.35e-1)" "unprognostic (8.13e-3)" "unprognostic (2.98e-3)" "unprognostic (1.92e-1)" "unprognostic (3.45e-1)" "unprognostic (1.61e-2)" "unprognostic (2.32e-1)" "unprognostic (9.85e-2)" "unprognostic (5.02e-2)" "unprognostic (3.52e-1)" "unprognostic (1.58e-1)" "unprognostic (1.05e-1)" ITGA7 ENSG00000135424 "Integrin subunit alpha 7" Q13683 12 55684568-55716404 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cell adhesion, Cell shape" "Integrin, Receptor" "Congenital muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 138.6;skeletal muscle: 135.6" "Cell type enriched" "Detected in many" 4 "Cardiomyocytes: 2187.9" "Cell type enhanced" "Detected in all" "astrocyte: 157.8;hippocampal dentate gyrus: 139.5;pericyte: 202.3;vascular associated smooth muscle cell: 227.6" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 76.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 22.5" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Fibroblasts, Minor Salivary Gland - Endothelial cells, Pancreas - Endothelial cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008427 Uncertain Approved "Nuclear speckles,Vesicles,Plasma membrane" NA NA 1100000 "Cluster 41: Striated muscle - Muscle contraction" "Cluster 29: Forebrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 6 "Plasma membrane" "Nuclear speckles, Vesicles" "HPA008427: " "unprognostic (4.28e-2)" "unprognostic (9.94e-2)" "unprognostic (7.21e-3)" "unprognostic (5.82e-3)" "unprognostic (5.72e-2)" "unprognostic (2.49e-2)" "unprognostic (3.37e-1)" "unprognostic (5.20e-3)" "unprognostic (2.06e-1)" "unprognostic (4.89e-1)" "potential prognostic favorable (9.29e-4)" "unprognostic (1.70e-3)" "unprognostic (1.03e-1)" "unprognostic (3.84e-1)" "unprognostic (2.86e-3)" "unprognostic (1.34e-1)" "unprognostic (7.24e-2)" "unprognostic (2.50e-3)" "unprognostic (4.41e-1)" "unprognostic (1.48e-1)" "unprognostic (4.07e-3)" "unprognostic (1.52e-2)" "unprognostic (4.28e-1)" "unprognostic (6.98e-2)" "unprognostic (4.04e-2)" "unprognostic (1.09e-1)" "unprognostic (4.83e-2)" "unprognostic (1.60e-1)" "unprognostic (2.22e-1)" "unprognostic (1.93e-2)" "unprognostic (1.74e-2)" ITGA8 ENSG00000077943 "Integrin subunit alpha 8" P53708 10 15513954-15719922 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Differentiation, Neurogenesis" "Developmental protein, Integrin, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "blood vessel: 353.6" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 87.2;Ependymal cells: 54.3;Fibro-adipogenic progenitors: 78.7;Fibroblasts: 82.9;Müller glia: 96.4;Oligodendrocyte progenitor cells: 108.6;Plasma cells: 105.9;Smooth muscle cells: 222.3;Vascular endothelial cells: 56.2;Vascular smooth muscle cells: 626.4" "Cell type enhanced" "Detected in all" "deep-layer near-projecting: 437.6;vascular associated smooth muscle cell: 654.5" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 9.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 13.8;Rhabdoid: 5.7" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Adrenal gland - Fibroblasts, Heart muscle - Smooth muscle cells, Minor Salivary Gland - Fibroblasts, Pituitary gland - Fibroblasts, Prostate - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Skin - Smooth muscle cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA003432 Enhanced Approved "Plasma membrane" NA NA 16000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 29: Forebrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 2 "Plasma membrane" "HPA003432: " "unprognostic (1.30e-2)" "unprognostic (1.26e-1)" "unprognostic (1.69e-1)" "unprognostic (1.13e-2)" "unprognostic (4.30e-1)" "unprognostic (1.74e-2)" "unprognostic (1.19e-1)" "unprognostic (2.04e-2)" "validated prognostic favorable (1.19e-13)" "validated prognostic favorable (4.59e-4)" "unprognostic (5.50e-2)" "unprognostic (1.10e-3)" "unprognostic (2.17e-1)" "unprognostic (5.81e-2)" "unprognostic (8.22e-2)" "unprognostic (7.75e-2)" "unprognostic (2.47e-1)" "unprognostic (9.35e-2)" "unprognostic (4.37e-2)" "unprognostic (2.07e-1)" "unprognostic (1.09e-1)" "unprognostic (1.37e-1)" "unprognostic (4.67e-2)" ITGA9 "ALPHA-RLC, ITGA4L, RLC" ENSG00000144668 "Integrin subunit alpha 9" Q13797 3 37452115-37823507 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 451.1;Cardiomyocytes: 259.0;Hematopoietic stem cells: 610.4;Hepatic stellate cells: 264.6;Kupffer cells: 369.0;Leydig cells: 433.5;Lymphatic endothelial cells: 519.8;Mast cells: 359.1;Megakaryocyte-Erythroid progenitors: 427.4;Peritubular myoid cells: 509.9;Transitional alveolar cells: 258.7;Vascular endothelial cells: 288.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Thyroid Carcinoma (TCGA): 37.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 10.3;testis cancer: 15.6" "Minor Salivary Gland - Endothelial cells, Prostate - Smooth muscle cells, Testis - Peritubular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030609 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cell Junctions" "Intracellular and membrane" Receptor NA NA 560000 "Cluster 35: Non-specific - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 3 Vesicles "Nucleoplasm, Plasma membrane, Cell Junctions" "HPA030609: " "unprognostic (2.19e-1)" "unprognostic (4.18e-2)" "unprognostic (4.23e-2)" "unprognostic (4.16e-1)" "unprognostic (1.62e-2)" "unprognostic (3.20e-1)" "unprognostic (1.34e-1)" "potential prognostic favorable (1.69e-4)" "unprognostic (3.03e-2)" "unprognostic (2.67e-3)" "potential prognostic favorable (6.21e-6)" "unprognostic (1.63e-2)" "unprognostic (5.70e-2)" "unprognostic (1.15e-1)" "unprognostic (7.07e-2)" "unprognostic (2.35e-3)" "unprognostic (5.96e-2)" "unprognostic (2.86e-1)" "unprognostic (1.18e-1)" "unprognostic (1.44e-1)" "unprognostic (2.15e-1)" "unprognostic (4.65e-1)" "unprognostic (5.68e-3)" "unprognostic (2.68e-2)" "unprognostic (2.59e-1)" "unprognostic (4.89e-2)" "unprognostic (9.80e-2)" "unprognostic (4.72e-2)" "unprognostic (1.28e-1)" "unprognostic (5.79e-2)" "unprognostic (1.23e-2)" ITGAD "ADB2, CD11d" ENSG00000156886 "Integrin subunit alpha D" Q13349 16 31393335-31426505 "CD markers, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 19.4" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 77.4;Innate lymphoid cells: 13.1;Kupffer cells: 54.3;Macrophages: 11.1;Myonuclei: 22.5;Neutrophils: 46.2;NK-cells: 9.5;Retinal ganglion cells: 11.6;Thymic myoid cells: 12.2" "Group enriched" "Detected in some" 4 "central nervous system macrophage: 1.4;hippocampal dentate gyrus: 1.1;leukocyte: 3.8" "Cancer enhanced" "Detected in single" "Kidney Renal Papillary Cell Carcinoma (TCGA): 1.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - T-cells, Kidney - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA026786 Uncertain NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 25 "HPA026786: " "unprognostic (1.52e-1)" "unprognostic (4.68e-2)" "unprognostic (1.06e-1)" "unprognostic (1.17e-3)" ITGAE "CD103, HUMINAE" ENSG00000083457 "Integrin subunit alpha E" P38570 17 3714628-3801188 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.1;intestine: 5.5;lung: 6.2" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 152.1;Esophageal suprabasal cells: 158.5;Late primary spermatocytes: 210.1;NK-cells: 152.1" "Cell type enhanced" "Detected in all" "leukocyte: 73.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "memory CD8 T-cell: 3.7" "Lineage enriched" "Detected in single" 6 "T-cells: 3.7" "Group enriched" "Detected in some" 11 "Leukemia: 1.7;lymphoma: 2.5" "Spleen - B-cells (Spleen), Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA036313, HPA052147" Enhanced NA NA 94000 "Cluster 27: T-cells - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 33: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" "HPA036313: , HPA052147: " "unprognostic (1.73e-1)" "unprognostic (1.45e-2)" "unprognostic (5.26e-1)" "unprognostic (8.32e-3)" "unprognostic (1.18e-2)" "unprognostic (7.58e-2)" "unprognostic (1.20e-2)" "unprognostic (2.02e-3)" "unprognostic (7.24e-3)" "unprognostic (7.82e-3)" "unprognostic (2.87e-2)" "unprognostic (2.07e-1)" "unprognostic (8.53e-2)" "unprognostic (1.70e-1)" "unprognostic (2.43e-1)" "unprognostic (4.22e-2)" "unprognostic (4.16e-2)" "unprognostic (3.81e-2)" "unprognostic (4.38e-3)" "unprognostic (8.82e-2)" "unprognostic (4.75e-2)" "unprognostic (3.41e-1)" ITGAL "CD11A, LFA-1, LFA1A" ENSG00000005844 "Integrin subunit alpha L" P20701 16 30472658-30523567 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Host-virus interaction, Phagocytosis" "Integrin, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 34.9;lymphoid tissue: 58.7" "Cell type enhanced" "Detected in many" "B-cells: 53.7;Microglia: 56.3;monocytes: 98.3;Neutrophil progenitors: 77.4;Neutrophils: 310.8;NK-cells: 292.9;pDCs: 60.3;Plasma cells: 56.2;Retinal ganglion cells: 57.9;T-cells: 186.8;Thymocytes: 99.9" "Cell type enriched" "Detected in many" 5 "leukocyte: 391.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 122.4" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 95 "Leukemia: 76.8;lymphoma: 43.9;Myeloma: 52.9" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Minor Salivary Gland - T-cells, Pancreas - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Skeletal muscle - Fibroblasts, Spleen - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB025011 Enhanced NA NA 4400000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 7 "CAB025011: " "unprognostic (1.70e-1)" "unprognostic (1.30e-2)" "potential prognostic favorable (4.34e-4)" "unprognostic (2.50e-2)" "unprognostic (1.60e-2)" "unprognostic (2.82e-1)" "unprognostic (6.44e-2)" "unprognostic (4.83e-2)" "potential prognostic favorable (8.09e-4)" "unprognostic (4.51e-1)" "unprognostic (8.80e-3)" "unprognostic (2.59e-1)" "unprognostic (6.15e-2)" "unprognostic (2.47e-1)" "unprognostic (7.68e-3)" "unprognostic (1.87e-3)" "unprognostic (1.99e-1)" "unprognostic (2.77e-1)" "unprognostic (4.85e-1)" "unprognostic (6.30e-2)" "unprognostic (5.52e-2)" "unprognostic (1.05e-1)" "unprognostic (1.77e-2)" "unprognostic (1.25e-1)" "unprognostic (3.93e-2)" "unprognostic (2.82e-2)" "unprognostic (5.35e-2)" "unprognostic (3.56e-1)" "unprognostic (4.25e-2)" "unprognostic (3.34e-1)" "unprognostic (1.64e-1)" ITGAM "CD11B, CR3A, MAC-1" ENSG00000169896 "Integrin subunit alpha M" P11215 16 31259967-31332892 "Cancer-related genes, CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Immunity, Innate immunity" "Integrin, Receptor" "Cancer-related genes, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "bone marrow: 172.8" "Cell type enhanced" "Detected in many" "cDC: 94.6;Hofbauer cells: 96.0;Kupffer cells: 97.4;Macrophages: 116.8;Mast cells: 82.2;Microglia: 200.5;Monocyte progenitors: 119.9;monocytes: 229.9;Neutrophil progenitors: 685.8;Neutrophils: 730.8;NK-cells: 98.7;pDCs: 86.5" "Cell type enriched" "Detected in some" 4 "central nervous system macrophage: 246.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in some" 8 "Leukemia: 11.3" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Lung - Neutrophils_2, Minor Salivary Gland - Macrophages, Skeletal muscle - Macrophages, Spleen - Neutrophils_2, Thyroid gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002274, CAB025091, CAB072870" Enhanced NA NA 730000 "Cluster 41: Basophils - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 37 "CAB025091: , CAB072870: , HPA002274: " "unprognostic (3.46e-2)" "unprognostic (7.29e-3)" "unprognostic (4.18e-2)" "unprognostic (9.23e-2)" "unprognostic (1.34e-1)" "unprognostic (3.53e-1)" "unprognostic (4.04e-2)" "unprognostic (4.01e-2)" "unprognostic (1.04e-1)" "unprognostic (1.03e-1)" "unprognostic (6.56e-2)" "unprognostic (3.16e-2)" "unprognostic (3.46e-1)" "potential prognostic unfavorable (1.80e-4)" "unprognostic (2.54e-2)" "unprognostic (3.05e-2)" "unprognostic (1.87e-2)" "unprognostic (6.91e-2)" "unprognostic (3.55e-1)" "unprognostic (1.01e-2)" "unprognostic (2.80e-1)" "unprognostic (9.16e-2)" "unprognostic (1.20e-1)" "unprognostic (1.59e-1)" "unprognostic (7.95e-3)" "unprognostic (1.69e-3)" "unprognostic (2.41e-1)" "unprognostic (4.84e-2)" "unprognostic (1.27e-3)" "unprognostic (3.25e-2)" "unprognostic (1.14e-1)" ITGAV "CD51, MSK8, VNRA, VTNR" ENSG00000138448 "Integrin subunit alpha V" P06756 2 186590010-186680901 "Cancer-related genes, CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Podocytes: 947.0;Retinal pigment epithelial cells: 3065.1;Urothelial cells: 624.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in all" "testis cancer: 265.2" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002499, HPA004856" Supported Approved "Focal adhesion sites,Cytosol" NA NA 250000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 35: Non-specific - Mixed function" "Cluster 27: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" 26 "Focal adhesion sites, Cytosol" "CAB002499: , HPA004856: " "unprognostic (6.72e-2)" "unprognostic (1.55e-2)" "unprognostic (1.21e-1)" "potential prognostic unfavorable (9.83e-4)" "unprognostic (4.26e-1)" "unprognostic (4.39e-2)" "unprognostic (3.53e-1)" "unprognostic (1.32e-1)" "unprognostic (2.07e-1)" "unprognostic (9.40e-2)" "potential prognostic favorable (4.05e-8)" "unprognostic (1.08e-2)" "unprognostic (2.13e-3)" "potential prognostic unfavorable (3.68e-4)" "unprognostic (1.57e-1)" "unprognostic (1.44e-3)" "potential prognostic unfavorable (7.00e-5)" "unprognostic (1.90e-1)" "unprognostic (6.01e-2)" "unprognostic (2.33e-1)" "unprognostic (1.27e-2)" "unprognostic (1.42e-3)" "unprognostic (1.66e-1)" "unprognostic (6.94e-2)" "unprognostic (3.17e-1)" "unprognostic (3.36e-2)" "unprognostic (6.85e-2)" "potential prognostic unfavorable (6.45e-5)" "unprognostic (1.29e-1)" "unprognostic (9.28e-2)" "unprognostic (1.20e-1)" ITGAX CD11C ENSG00000140678 "Integrin subunit alpha X" P20702 16 31355134-31382999 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 45.4;lung: 56.9;lymphoid tissue: 66.2" "Cell type enhanced" "Detected in some" "cDC: 292.5;Macrophages: 204.2;Mast cells: 195.6;Microglia: 386.4;monocytes: 557.7;Neutrophils: 1628.0" "Cell type enriched" "Detected in some" 5 "central nervous system macrophage: 457.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 86.3" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Leukemia: 7.5;lymphoma: 7.8" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Kidney - T-cells, Liver - Neutrophils, Skeletal muscle - Neutrophils, Spleen - Neutrophils_2, Thyroid gland - T-cells" "Not detected" "Not detected" "CAB004458, HPA004723, CAB072871, CAB080214" Enhanced Supported "Vesicles,Plasma membrane" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 49: HMC-1 - Innate immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 2 "Vesicles, Plasma membrane" "CAB004458: , CAB072871: , CAB080214: , HPA004723: " "unprognostic (1.92e-1)" "unprognostic (5.48e-3)" "unprognostic (1.24e-2)" "unprognostic (3.52e-1)" "unprognostic (8.23e-2)" "unprognostic (5.35e-2)" "unprognostic (9.77e-2)" "unprognostic (9.55e-2)" "unprognostic (8.97e-2)" "unprognostic (1.44e-1)" "unprognostic (6.02e-2)" "unprognostic (3.16e-1)" "unprognostic (3.37e-1)" "unprognostic (4.36e-2)" "unprognostic (8.16e-2)" "unprognostic (3.47e-2)" "unprognostic (1.31e-2)" "unprognostic (4.74e-2)" "unprognostic (2.19e-1)" "unprognostic (1.84e-1)" "unprognostic (1.98e-1)" "unprognostic (7.07e-2)" "unprognostic (1.04e-2)" "unprognostic (3.64e-1)" "unprognostic (3.27e-2)" "unprognostic (2.77e-3)" "unprognostic (2.49e-2)" "unprognostic (3.41e-2)" "unprognostic (5.05e-2)" "unprognostic (2.49e-1)" "unprognostic (2.62e-1)" ITGB1 "CD29, FNRB, GPIIA, MDF2, MSK12" ENSG00000150093 "Integrin subunit beta 1" P05556 10 32887273-33005792 "Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Host-virus interaction, Myogenesis" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial glandular cells: 770.3;Pancreatic duct cells: 750.3;Platelets: 1111.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003434, HPA059297, HPA069003" Enhanced Supported "Endoplasmic reticulum,Plasma membrane,Focal adhesion sites" NA NA 69000000 "Cluster 16: Non-specific - Cell proliferation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 47: Endothelial cells - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 62: Smooth muscle cells - Muscle contraction" 97 "Plasma membrane, Focal adhesion sites" "Endoplasmic reticulum" "CAB003434: , HPA059297: , HPA069003: " "unprognostic (4.54e-2)" "unprognostic (6.31e-2)" "unprognostic (2.88e-1)" "unprognostic (5.64e-3)" "unprognostic (2.25e-1)" "unprognostic (3.28e-2)" "unprognostic (7.99e-2)" "unprognostic (3.49e-2)" "unprognostic (1.17e-2)" "unprognostic (2.98e-3)" "potential prognostic favorable (4.33e-4)" "unprognostic (1.02e-1)" "unprognostic (1.79e-2)" "unprognostic (2.23e-3)" "unprognostic (8.77e-2)" "validated prognostic unfavorable (1.05e-5)" "validated prognostic unfavorable (7.17e-4)" "potential prognostic unfavorable (2.85e-4)" "unprognostic (2.00e-2)" "unprognostic (1.71e-2)" "potential prognostic unfavorable (7.34e-4)" "unprognostic (1.55e-3)" "unprognostic (1.99e-2)" "unprognostic (2.03e-1)" "unprognostic (2.51e-1)" "unprognostic (5.64e-2)" "unprognostic (2.77e-1)" "unprognostic (4.34e-3)" "unprognostic (3.02e-1)" "unprognostic (9.42e-2)" "unprognostic (1.39e-1)" ITGB1BP1 "ICAP-1A, ICAP-1alpha, ICAP-1B, ICAP1, ICAP1A, ICAP1B" ENSG00000119185 "Integrin subunit beta 1 binding protein 1" O14713 2 9403475-9423528 "Predicted intracellular proteins, Transporters" "Angiogenesis, Biomineralization, Cell adhesion, Differentiation, Notch signaling pathway, Transcription, Transcription regulation" Mitogen "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Minor Salivary Gland - Endothelial cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067348, HPA071538" Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 108: Fibroblasts - ECM organization" 14 Nucleoplasm "Nuclear bodies, Cytosol" "HPA067348: , HPA071538: " "unprognostic (1.68e-3)" "unprognostic (6.64e-2)" "unprognostic (3.33e-1)" "potential prognostic unfavorable (2.37e-4)" "unprognostic (3.56e-2)" "unprognostic (6.81e-3)" "unprognostic (5.97e-2)" "unprognostic (1.45e-1)" "potential prognostic unfavorable (4.39e-4)" "unprognostic (4.26e-2)" "unprognostic (8.19e-3)" "unprognostic (2.94e-3)" "unprognostic (9.38e-3)" "validated prognostic unfavorable (6.43e-8)" "validated prognostic unfavorable (1.48e-6)" "unprognostic (1.03e-1)" "unprognostic (5.74e-2)" "unprognostic (2.91e-1)" "unprognostic (1.01e-1)" "unprognostic (1.88e-1)" "unprognostic (2.47e-1)" "unprognostic (4.95e-2)" "unprognostic (1.31e-1)" "unprognostic (7.87e-2)" "unprognostic (1.70e-2)" "unprognostic (1.57e-2)" "unprognostic (2.52e-1)" "unprognostic (5.14e-1)" "unprognostic (2.61e-2)" "unprognostic (8.78e-3)" "potential prognostic unfavorable (2.94e-4)" ITGB1BP2 CHORDC3 ENSG00000147166 "Integrin subunit beta 1 binding protein 2" Q9UKP3 X 71301750-71305371 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 85.6;skeletal muscle: 43.2;tongue: 49.5" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 4.9;Megakaryocytes: 6.2;Myonuclei: 4.6;Peritubular myoid cells: 8.1;Retinal horizontal cells: 2.0;Smooth muscle cells: 5.0;Vascular smooth muscle cells: 3.0" "Cell type enriched" "Detected in single" 5 "vascular associated smooth muscle cell: 3.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Colon - Smooth muscle cells, Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA040721 Approved Cytosol NA NA "Cluster 41: Striated muscle - Muscle contraction" "Cluster 25: Non-specific - Transcription" "Cluster 35: RS4;11 - Unknown function" "Cluster 62: Smooth muscle cells - Muscle contraction" 14 Cytosol "HPA040721: " "unprognostic (8.68e-2)" "unprognostic (2.64e-1)" "unprognostic (1.05e-1)" "unprognostic (5.63e-2)" "unprognostic (6.42e-2)" "unprognostic (2.46e-1)" "unprognostic (9.73e-2)" "unprognostic (7.09e-2)" "unprognostic (6.58e-2)" "unprognostic (2.18e-2)" "unprognostic (1.61e-1)" ITGB2 "CD18, LFA-1, MAC-1, MFI7" ENSG00000160255 "Integrin subunit beta 2" P05107 21 44885953-44931989 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Phagocytosis" "Integrin, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 343.1;lymphoid tissue: 162.7" "Cell type enhanced" "Detected in many" "cDC: 399.5;Hofbauer cells: 522.8;Kupffer cells: 222.4;Macrophages: 344.6;Monocyte progenitors: 358.2;monocytes: 613.7;Neutrophil progenitors: 309.9;Neutrophils: 726.1;NK-cells: 269.4;T-cells: 148.4" "Group enriched" "Detected in some" 15 "central nervous system macrophage: 126.3;leukocyte: 200.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Bone cancer: 64.2;Leukemia: 194.5;lymphoma: 74.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Spleen - Neutrophils_2, Stomach - Macrophages, Testis - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008877, HPA016894" Enhanced Supported "Plasma membrane,Rods & Rings" NA NA 5100000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 34 "Plasma membrane" "Rods & Rings" "HPA008877: , HPA016894: " "unprognostic (4.81e-2)" "unprognostic (4.76e-2)" "unprognostic (2.34e-2)" "unprognostic (5.75e-2)" "unprognostic (8.94e-2)" "unprognostic (1.28e-1)" "unprognostic (5.59e-3)" "unprognostic (2.22e-1)" "unprognostic (8.19e-2)" "unprognostic (3.35e-1)" "unprognostic (1.78e-3)" "unprognostic (2.33e-1)" "unprognostic (3.55e-1)" "unprognostic (1.18e-1)" "unprognostic (2.03e-1)" "unprognostic (1.74e-1)" "unprognostic (2.15e-2)" "unprognostic (2.83e-1)" "unprognostic (1.03e-1)" "unprognostic (5.88e-2)" "unprognostic (4.43e-1)" "unprognostic (1.60e-1)" "unprognostic (9.67e-2)" "unprognostic (1.04e-1)" "unprognostic (8.46e-2)" "unprognostic (1.94e-2)" "unprognostic (1.12e-1)" "unprognostic (8.14e-2)" "unprognostic (2.13e-2)" "unprognostic (1.74e-1)" "unprognostic (1.08e-2)" ITGB3 "CD61, GP3A, GPIIIa" ENSG00000259207 "Integrin subunit beta 3" P05106 17 47253827-47313743 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 37.6;thyroid gland: 52.7" "Cell type enriched" "Detected in some" 6 "Platelets: 76.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 42.7;Thyroid Carcinoma (TCGA): 54.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 17 "basophil: 5.6;neutrophil: 3.0" "Lineage enriched" "Detected in single" 22 "granulocytes: 5.6" "Cancer enhanced" "Detected in many" "Kidney cancer: 99.0;skin cancer: 125.1" "Liver - Vascular endothelial cells, Pituitary gland - Endothelial cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA027852 Approved Supported "Nucleoplasm,Plasma membrane" "Intracellular and membrane" Receptor NA NA 74000000 "Cluster 35: Neutrophils - Protein binding" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 12: Non-specific - Vasculature" "Cluster 69: Skin cancer - ECM organization" "Cluster 47: Platelets - Hemostasis" 26 "Plasma membrane" Nucleoplasm "HPA027852: " "unprognostic (3.07e-1)" "unprognostic (5.14e-2)" "unprognostic (1.97e-1)" "potential prognostic unfavorable (1.29e-5)" "unprognostic (2.03e-1)" "unprognostic (1.00e-1)" "unprognostic (1.08e-2)" "unprognostic (2.19e-2)" "unprognostic (6.47e-3)" "potential prognostic unfavorable (6.40e-4)" "unprognostic (1.20e-3)" "unprognostic (2.55e-1)" "unprognostic (1.55e-1)" "unprognostic (4.08e-1)" "unprognostic (8.90e-2)" "unprognostic (1.38e-1)" "potential prognostic unfavorable (1.51e-4)" "unprognostic (6.12e-2)" "potential prognostic unfavorable (8.56e-4)" "unprognostic (3.74e-1)" "unprognostic (2.11e-1)" "unprognostic (4.34e-2)" "unprognostic (1.34e-2)" "unprognostic (2.33e-2)" "unprognostic (8.62e-2)" "unprognostic (8.26e-2)" "unprognostic (5.73e-2)" "unprognostic (6.30e-3)" "unprognostic (3.24e-1)" "unprognostic (2.20e-1)" "unprognostic (3.83e-2)" ITGB3BP "CENPR, HSU37139, NRIF3, TAP20" ENSG00000142856 "Integrin subunit beta 3 binding protein" Q13352 1 63440770-63593721 "Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Mitosis, Transcription, Transcription regulation" "Activator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1191.7;Late primary spermatocytes: 322.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" HPA028463 Approved Supported Nucleoplasm NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 61: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 45 Nucleoplasm "HPA028463: " "unprognostic (8.79e-2)" "unprognostic (1.27e-1)" "unprognostic (3.08e-3)" "potential prognostic favorable (6.90e-4)" "unprognostic (8.47e-3)" "unprognostic (5.65e-2)" "unprognostic (3.67e-2)" "unprognostic (3.61e-1)" "unprognostic (2.63e-2)" "unprognostic (1.57e-1)" "unprognostic (8.68e-2)" "unprognostic (8.48e-2)" "unprognostic (1.24e-1)" "potential prognostic unfavorable (3.51e-5)" "unprognostic (9.62e-3)" "unprognostic (1.98e-2)" "unprognostic (5.24e-3)" "unprognostic (9.23e-2)" "unprognostic (6.50e-2)" "unprognostic (4.19e-3)" "unprognostic (5.63e-2)" "unprognostic (3.73e-2)" "unprognostic (5.72e-3)" "unprognostic (4.38e-3)" "unprognostic (5.98e-2)" "unprognostic (1.53e-1)" "unprognostic (3.49e-2)" "unprognostic (5.28e-2)" "unprognostic (2.17e-1)" "unprognostic (2.31e-2)" "unprognostic (2.03e-1)" ITGB4 CD104 ENSG00000132470 "Integrin subunit beta 4" P16144 17 75721328-75757818 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes, Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 198.1;skin 1: 198.6" "Cell type enhanced" "Detected in many" "Foveolar cells: 218.4;Respiratory basal cells: 233.5;Salivary basal cells: 319.2;Salivary myoepithelial cells: 212.2;Schwann cells: 309.7" "Group enriched" "Detected in many" 5 "astrocyte: 182.1;Bergmann glia: 78.1;ependymal cell: 126.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 4.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Endothelial cells, Spleen - Endothelial cells, Stomach - Gastric mucous cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 49.5" "CAB002422, CAB005258, HPA036348, HPA036349" Enhanced Supported "Plasma membrane,Cell Junctions" NA NA 160000 "Cluster 30: Non-specific - DNA binding" "Cluster 2: Non-specific - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 61: Schwann cells & Melanocytes - Mixed function" 14 "Plasma membrane, Cell Junctions" "CAB002422: , CAB005258: , HPA036348: , HPA036349: " "unprognostic (3.96e-2)" "unprognostic (3.58e-3)" "unprognostic (2.19e-2)" "unprognostic (1.14e-1)" "unprognostic (1.69e-1)" "unprognostic (3.28e-1)" "unprognostic (9.55e-3)" "unprognostic (2.98e-2)" "unprognostic (2.32e-2)" "unprognostic (1.44e-1)" "potential prognostic unfavorable (6.61e-6)" "unprognostic (1.89e-1)" "unprognostic (3.45e-2)" "unprognostic (4.45e-3)" "unprognostic (6.51e-2)" "potential prognostic unfavorable (1.75e-5)" "unprognostic (2.89e-1)" "unprognostic (3.27e-1)" "unprognostic (1.34e-1)" "unprognostic (8.15e-2)" "unprognostic (1.49e-2)" "unprognostic (1.62e-2)" "unprognostic (1.28e-1)" "unprognostic (3.41e-2)" "unprognostic (1.03e-1)" "unprognostic (5.67e-2)" "unprognostic (8.89e-2)" "unprognostic (4.26e-2)" "unprognostic (3.27e-2)" "unprognostic (1.10e-1)" "unprognostic (1.47e-1)" ITGB5 ENSG00000082781 "Integrin subunit beta 5" P18084 3 124761948-124901418 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 290.3" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 223.0;Hofbauer cells: 230.0;Platelets: 419.7;Podocytes: 308.9" "Cell type enhanced" "Detected in many" "Bergmann glia: 188.5;central nervous system macrophage: 201.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001820, CAB022050" Enhanced Approved "Plasma membrane,Mitochondria" NA NA 240000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 39 "Plasma membrane, Mitochondria" "CAB022050: , HPA001820: " "unprognostic (2.49e-1)" "unprognostic (2.43e-1)" "unprognostic (7.11e-2)" "unprognostic (2.09e-3)" "unprognostic (3.44e-1)" "unprognostic (1.10e-2)" "unprognostic (2.02e-2)" "potential prognostic unfavorable (2.97e-4)" "unprognostic (1.54e-1)" "potential prognostic unfavorable (8.73e-4)" "potential prognostic favorable (1.99e-6)" "unprognostic (6.84e-2)" "unprognostic (5.23e-2)" "unprognostic (1.02e-3)" "unprognostic (2.80e-3)" "unprognostic (1.64e-2)" "unprognostic (1.40e-3)" "unprognostic (1.99e-2)" "unprognostic (1.42e-1)" "unprognostic (9.64e-3)" "unprognostic (2.36e-3)" "unprognostic (1.74e-3)" "unprognostic (7.93e-2)" "unprognostic (3.92e-2)" "unprognostic (1.20e-1)" "unprognostic (6.36e-2)" "unprognostic (1.11e-1)" "unprognostic (5.76e-2)" "unprognostic (1.33e-1)" "unprognostic (5.28e-2)" "unprognostic (3.48e-1)" ITGB6 ENSG00000115221 "Integrin subunit beta 6" P18564 2 160099667-160200313 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Amelogenesis imperfecta, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 74.9;tongue: 60.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 147.9;Alveolar cells type 2: 153.2;Distal convoluted tubule cells: 245.5;Epididymal basal cells: 278.9;Loop of henle epithelial cells: 447.4;Myonuclei: 187.5;Papillary tip epithelial cells: 465.8;Prostatic club cells: 152.4;Proximal tubule cells: 129.6;Renal collecting duct principal cells: 170.9;Renal connecting tubule cells: 345.5;Urothelial cells: 272.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Pancreas - Ductal cells, Prostate - Urothelial cells, Skeletal muscle - Skeletal myocytes, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA023626, CAB073536" Approved Approved "Nucleoplasm,Cell Junctions,Centrosome,Acrosome,Connecting piece,Mid piece,Principal piece,End piece" NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 3 "Nucleoplasm, Cell Junctions, Acrosome" "Centrosome, Connecting piece, Mid piece, Principal piece, End piece" "CAB073536: , HPA023626: " "unprognostic (6.61e-2)" "unprognostic (8.85e-2)" "unprognostic (5.56e-2)" "potential prognostic unfavorable (6.85e-4)" "unprognostic (1.01e-1)" "unprognostic (1.41e-1)" "unprognostic (1.29e-2)" "unprognostic (4.79e-2)" "unprognostic (3.58e-2)" "unprognostic (1.04e-1)" "unprognostic (1.13e-1)" "unprognostic (1.09e-1)" "unprognostic (2.40e-1)" "unprognostic (3.72e-1)" "unprognostic (1.70e-3)" "unprognostic (1.07e-2)" "unprognostic (1.08e-2)" "potential prognostic unfavorable (5.24e-4)" "potential prognostic unfavorable (7.31e-6)" "unprognostic (7.65e-2)" "unprognostic (7.05e-2)" "unprognostic (4.46e-1)" "unprognostic (1.07e-2)" "unprognostic (3.74e-2)" "unprognostic (1.37e-1)" "unprognostic (1.39e-1)" ITGB7 ENSG00000139626 "Integrin subunit beta 7" P26010 12 53191323-53207282 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 29.1" "Cell type enhanced" "Detected in many" "B-cells: 21.4;cDC: 16.6;Innate lymphoid cells: 35.8;NK-cells: 40.3;pDCs: 15.4;Plasma cells: 69.6;T-cells: 34.0;Thymocytes: 16.9" "Cell type enriched" "Detected in some" 5 "leukocyte: 38.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in many" 18 "Myeloma: 982.6" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Lung - T-cells, Prostate - T-cells, Thyroid gland - T-cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA042277 Approved "Plasma membrane,Cytosol" NA NA 390000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 3 "Plasma membrane, Cytosol" "HPA042277: " "unprognostic (8.50e-2)" "unprognostic (1.92e-2)" "unprognostic (1.38e-2)" "unprognostic (9.63e-3)" "unprognostic (7.07e-2)" "unprognostic (1.69e-1)" "potential prognostic unfavorable (9.37e-4)" "unprognostic (1.30e-1)" "potential prognostic favorable (1.09e-4)" "unprognostic (1.40e-1)" "unprognostic (1.88e-1)" "unprognostic (4.53e-2)" "unprognostic (3.70e-3)" "potential prognostic favorable (9.95e-4)" "unprognostic (1.40e-1)" "unprognostic (1.98e-3)" "unprognostic (8.08e-2)" "unprognostic (1.99e-1)" "unprognostic (1.43e-1)" "unprognostic (2.33e-1)" "unprognostic (7.97e-3)" "potential prognostic unfavorable (6.63e-4)" "unprognostic (1.70e-1)" "unprognostic (1.75e-1)" "unprognostic (8.16e-2)" "unprognostic (1.85e-1)" "unprognostic (1.33e-2)" "unprognostic (5.55e-1)" "unprognostic (8.27e-2)" "unprognostic (2.11e-2)" "unprognostic (7.71e-2)" ITGB8 ENSG00000105855 "Integrin subunit beta 8" P26012 7 20330702-20415754 "Cancer-related genes, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 1689.6;Endometrial glandular cells: 2649.4;Endometrial luminal cells: 1866.7;Endometrial secretory cells: 1319.1;Pituicytes/FSCs: 1417.8;Podocytes: 1445.4;Retinal pigment epithelial cells: 2285.0;Schwann cells: 966.0" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 459.9;ependymal cell: 428.3" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 111.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 134 "basophil: 16.4" "Lineage enriched" "Detected in single" 134 "granulocytes: 16.4" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Liver - Cholangiocytes, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027796, HPA027797" Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 39: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 51: Secretory epithelial cells - Mixed function" 7 "Plasma membrane, Cytosol" "HPA027796: , HPA027797: " "unprognostic (1.09e-1)" "unprognostic (2.40e-2)" "unprognostic (3.00e-1)" "unprognostic (2.19e-1)" "unprognostic (4.03e-2)" "unprognostic (1.34e-2)" "unprognostic (1.59e-1)" "potential prognostic unfavorable (7.27e-5)" "unprognostic (2.96e-1)" "unprognostic (2.43e-1)" "potential prognostic favorable (4.65e-6)" "unprognostic (3.62e-2)" "unprognostic (2.97e-3)" "unprognostic (6.66e-2)" "unprognostic (1.64e-2)" "unprognostic (3.12e-3)" "unprognostic (6.54e-3)" "unprognostic (3.33e-1)" "unprognostic (1.26e-2)" "unprognostic (6.00e-3)" "unprognostic (5.85e-3)" "unprognostic (2.59e-1)" "unprognostic (7.97e-2)" "unprognostic (1.56e-1)" "unprognostic (8.83e-2)" "unprognostic (2.23e-2)" "unprognostic (2.19e-1)" "unprognostic (8.63e-2)" "unprognostic (7.03e-2)" "unprognostic (6.09e-2)" ITGBL1 "OSCP, TIED" ENSG00000198542 "Integrin subunit beta like 1" O95965 13 101452593-101720856 "Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "blood vessel: 156.8" "Cell type enhanced" "Detected in many" "Fibro-adipogenic progenitors: 178.0;Fibroblasts: 161.2;Gonadotrophs: 280.0;Hepatic stellate cells: 180.7;Myosatellite cells: 229.5;Pituicytes/FSCs: 281.1;Pituitary stem cells: 241.7;Retinal pigment epithelial cells: 196.1;Salivary myoepithelial cells: 165.1;Somatotrophs: 146.0;Thymic myoid cells: 335.8" "Cell type enhanced" "Detected in many" "fibroblast: 162.8" "Cancer enhanced" "Detected in all" "Pancreatic Adenocarcinoma (TCGA): 59.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 73.5" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Fibroblasts, Colon - Fibroblasts, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts, Spleen - Smooth muscle cells, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 12 "spinal cord: 75.1" "Secreted - unknown location" "No annotated function" NA NA 64000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 25: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" "unprognostic (3.60e-3)" "unprognostic (2.85e-1)" "unprognostic (7.82e-3)" "unprognostic (5.61e-2)" "unprognostic (1.79e-3)" "unprognostic (1.50e-2)" "potential prognostic unfavorable (2.64e-5)" "unprognostic (1.19e-3)" "unprognostic (1.49e-1)" "unprognostic (2.02e-1)" "unprognostic (3.66e-1)" "unprognostic (1.50e-1)" "potential prognostic unfavorable (6.29e-7)" "unprognostic (1.07e-1)" "unprognostic (3.16e-3)" "unprognostic (1.56e-1)" "unprognostic (3.56e-1)" "unprognostic (3.26e-2)" "unprognostic (6.23e-2)" "unprognostic (6.77e-2)" "potential prognostic unfavorable (7.38e-6)" "unprognostic (3.70e-2)" "unprognostic (9.30e-3)" "unprognostic (1.18e-1)" "unprognostic (8.91e-2)" "unprognostic (2.22e-2)" "unprognostic (5.49e-2)" "unprognostic (1.28e-2)" "unprognostic (1.88e-1)" "unprognostic (1.22e-1)" "unprognostic (8.90e-2)" ITIH1 "H1P, IATIH, ITIH" ENSG00000055957 "Inter-alpha-trypsin inhibitor heavy chain 1" P19827 3 52777595-52792068 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 642 "liver: 1407.7" "Cell type enriched" "Detected in some" 65 "Hepatocytes: 1290.5" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 457 "Liver Hepatocellular Carcinoma (TCGA): 775.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041639, HPA042049" Approved Approved Vesicles "Secreted to blood" "Enzyme inhibitor" NA NA 4490000 110000000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 18: Liver cancer - Metabolism" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 4 Vesicles "HPA041639: , HPA042049: " "unprognostic (3.87e-3)" "potential prognostic favorable (4.54e-4)" "unprognostic (3.00e-3)" ITIH2 H2P ENSG00000151655 "Inter-alpha-trypsin inhibitor heavy chain 2" P19823 10 7703316-7749520 "Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 561 "liver: 2016.4" "Cell type enriched" "Detected in some" 4 "Hepatocytes: 538.8" "Cell type enriched" "Detected in many" 29 "fibroblast: 184.1" "Cancer enriched" "Detected in many" 258 "Liver Hepatocellular Carcinoma (TCGA): 850.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 40 "liver cancer: 147.1" "Liver - Hepatocytes, Pituitary gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059150 Supported Approved "Golgi apparatus" "Secreted to blood" "Enzyme inhibitor" NA NA 62000000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 16: Non-specific - Transcription" "Cluster 18: Liver cancer - Metabolism" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 13 "Golgi apparatus" "HPA059150: " "unprognostic (1.34e-1)" "unprognostic (7.51e-2)" "unprognostic (4.93e-2)" "potential prognostic unfavorable (2.16e-4)" "unprognostic (2.04e-3)" "unprognostic (1.67e-2)" "unprognostic (1.93e-1)" "unprognostic (7.79e-2)" "unprognostic (1.45e-2)" "unprognostic (1.21e-1)" "unprognostic (1.39e-2)" "unprognostic (3.89e-3)" "unprognostic (1.66e-1)" "unprognostic (5.31e-3)" ITIH3 H3P ENSG00000162267 "Inter-alpha-trypsin inhibitor heavy chain 3" Q06033 3 52794768-52808799 "Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "liver: 798.4" "Cell type enriched" "Detected in some" 4 "Hepatocytes: 953.7" "Cell type enriched" "Detected in single" 38 "vascular associated smooth muscle cell: 20.2" "Cancer enriched" "Detected in some" 163 "Liver Hepatocellular Carcinoma (TCGA): 581.3" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 12 "liver cancer: 5.1" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Heart muscle - Smooth muscle cells, Lung - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Testis - Late spermatids, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA017373 Approved "Secreted to blood" "Enzyme inhibitor" NA NA 23000000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" "HPA017373: " "unprognostic (4.16e-1)" "potential prognostic unfavorable (2.35e-4)" "unprognostic (3.55e-1)" "unprognostic (6.00e-2)" "potential prognostic favorable (1.28e-6)" "unprognostic (8.18e-2)" "unprognostic (2.30e-1)" "unprognostic (2.12e-1)" ITIH4 "H4P, IHRP, ITIHL1" ENSG00000055955 "Inter-alpha-trypsin inhibitor heavy chain 4" Q14624 3 52812962-52830688 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 36 "liver: 1743.0" "Cell type enhanced" "Detected in some" "Astrocytes: 29.1;Bergmann glia: 10.3;Brain excitatory neurons: 14.5;Brain inhibitory neurons: 14.3;Ependymal cells: 8.4;Hepatocytes: 40.9;Microglia: 12.7;Myonuclei: 21.4;Other brain neurons: 12.7;Retinal ganglion cells: 15.5" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 104 "Liver Hepatocellular Carcinoma (TCGA): 656.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "liver cancer: 1.4" "Adipose subcutaneous - Smooth muscle cells, Liver - Hepatocytes, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA001835, HPA003948, CAB072872" Enhanced Approved Vesicles "Secreted to blood" "Acute phase" NA NA 3060000 98000000000 "Cluster 53: Liver - Plasma proteins" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 1 Vesicles "CAB072872: , HPA001835: , HPA003948: " "unprognostic (7.00e-2)" "unprognostic (7.97e-3)" "unprognostic (7.09e-2)" "unprognostic (1.62e-1)" "unprognostic (9.65e-2)" "potential prognostic unfavorable (7.53e-9)" "unprognostic (9.92e-3)" "unprognostic (3.63e-2)" "potential prognostic favorable (4.58e-7)" "unprognostic (6.57e-3)" "unprognostic (2.25e-1)" "unprognostic (2.72e-2)" "unprognostic (1.38e-2)" "unprognostic (1.10e-2)" "unprognostic (6.15e-2)" "potential prognostic unfavorable (3.89e-4)" "unprognostic (1.69e-1)" ITIH5 MGC10848 ENSG00000123243 "Inter-alpha-trypsin inhibitor heavy chain 5" 10 7559270-7666998 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 105.7" "Cell type enhanced" "Detected in many" "Adipocytes: 524.1;Cytotrophoblasts: 477.9;Epididymal clear cells: 224.5;Extravillous trophoblasts: 143.2;Fibro-adipogenic progenitors: 290.3;Migrating cytotrophoblasts: 219.7;Pericytes: 193.2;Podocytes: 311.0;Renal collecting duct intercalated cells: 209.5;Respiratory ionocytes: 149.9;Salivary ionocytes: 318.8;Smooth muscle cells: 206.0;Syncytiotrophoblasts: 300.2;Vascular smooth muscle cells: 221.1" "Cell type enhanced" "Detected in many" "fibroblast: 1370.1;pericyte: 1626.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Rhabdoid: 78.8;skin cancer: 68.8" "Liver - Hepatic stellate cells, Minor Salivary Gland - Fibroblasts, Prostate - Smooth muscle cells, Skeletal muscle - Fibroblasts, Skin - Fibroblasts_1, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038305 Approved Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 69: Skin cancer - ECM organization" "Cluster 22: Non-specific - Basic cellular functions" "Golgi apparatus" Vesicles "HPA038305: " "unprognostic (4.00e-2)" "unprognostic (2.25e-1)" "unprognostic (9.88e-3)" "unprognostic (2.31e-1)" "unprognostic (3.48e-2)" "unprognostic (2.46e-1)" "unprognostic (3.99e-2)" "unprognostic (4.95e-1)" "unprognostic (1.11e-2)" "unprognostic (1.50e-2)" "unprognostic (4.28e-3)" "unprognostic (6.09e-2)" "unprognostic (1.14e-1)" "unprognostic (2.41e-1)" "unprognostic (6.14e-2)" "unprognostic (1.54e-2)" "unprognostic (2.79e-2)" "unprognostic (1.07e-2)" "unprognostic (4.31e-3)" "unprognostic (1.99e-1)" "unprognostic (7.78e-2)" "unprognostic (3.31e-2)" "unprognostic (4.25e-2)" "unprognostic (4.01e-2)" "unprognostic (3.22e-1)" "unprognostic (2.34e-3)" "unprognostic (2.95e-2)" "unprognostic (4.61e-3)" "unprognostic (1.48e-1)" "unprognostic (1.70e-2)" "unprognostic (1.45e-2)" ITIH6 "ITIH5L, UNQ6369" ENSG00000102313 "Inter-alpha-trypsin inhibitor heavy chain family member 6" Q6UXX5 X 54748918-54798255 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "skeletal muscle: 1.4" "Cell type enriched" "Detected in some" 27 "Myonuclei: 387.9" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 8 "Skin Cutaneous Melanoma (TCGA): 18.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 11 "skin cancer: 11.3" "Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells" HPA000506 Uncertain "Secreted to blood" "Enzyme inhibitor" NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 69: Skin cancer - ECM organization" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 6 "HPA000506: " "unprognostic (3.17e-1)" "unprognostic (7.42e-3)" ITK "EMT, LYK, PSCTK2" ENSG00000113263 "IL2 inducible T cell kinase" Q08881 5 157142933-157255185 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Adaptive immunity, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "lymphoid tissue: 53.6" "Cell type enhanced" "Detected in many" "Early spermatids: 74.1;Innate lymphoid cells: 135.9;Mast cells: 125.3;NK-cells: 295.4;T-cells: 564.1" "Cell type enriched" "Detected in many" 55 "leukocyte: 398.8" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 22 "gdT-cell: 39.0;MAIT T-cell: 26.3;memory CD4 T-cell: 55.6;memory CD8 T-cell: 53.5;naive CD4 T-cell: 77.6;naive CD8 T-cell: 63.5;NK-cell: 28.7;T-reg: 70.2" "Group enriched" "Detected in many" 22 "NK-cells: 28.7;T-cells: 77.6" "Group enriched" "Detected in some" 23 "Leukemia: 7.3;lymphoma: 4.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Minor Salivary Gland - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Skin - T-cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA060674 Supported Cytosol NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" 26 Cytosol "HPA060674: " "unprognostic (4.18e-2)" "unprognostic (2.14e-2)" "unprognostic (4.06e-2)" "potential prognostic favorable (4.31e-5)" "unprognostic (5.88e-3)" "unprognostic (8.05e-3)" "potential prognostic favorable (5.83e-4)" "unprognostic (5.87e-2)" "unprognostic (1.30e-1)" "unprognostic (2.65e-1)" "unprognostic (2.46e-3)" "unprognostic (2.14e-1)" "unprognostic (1.87e-3)" ITLN1 "FLJ20022, hIntL, HL-1, ITLN, LFR" ENSG00000179914 "Intelectin 1" Q8WWA0 1 160876540-160885180 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adipose tissue: 714.6;intestine: 1172.6" "Cell type enriched" "Detected in some" 4 "Mesothelial cells: 8631.6" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Colon Adenocarcinoma (TCGA): 87.3;Lung Adenocarcinoma (TCGA): 53.0;Pancreatic Adenocarcinoma (TCGA): 73.5;Rectum Adenocarcinoma (TCGA): 117.2;Stomach Adenocarcinoma (TCGA): 56.5" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "intermediate monocyte: 9.2;non-classical monocyte: 24.2" "Lineage enriched" "Detected in many" 17 "monocytes: 24.2" "Cancer enhanced" "Detected in some" "Gastric cancer: 1.8;Leukemia: 1.4;liver cancer: 1.3" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Minor Salivary Gland - Minor salivary glandular cells" "Not detected" "Not detected" "CAB012652, HPA063275, HPA067326" Enhanced Approved "Vesicles,Acrosome,Equatorial segment,Mid piece,Principal piece" "Secreted to blood" "No annotated function" NA NA 294000000 5200000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 77: Intestine - Digestion" "Cluster 47: Leukemia - Hemostasis" "Cluster 70: Intestinal goblet cells - Mucin production" 39 "Vesicles, Equatorial segment" "Acrosome, Mid piece, Principal piece" "CAB012652: , HPA063275: , HPA067326: " "unprognostic (1.71e-1)" "unprognostic (2.25e-3)" "unprognostic (4.86e-2)" "unprognostic (1.42e-1)" "unprognostic (1.70e-2)" "unprognostic (1.11e-1)" "unprognostic (7.84e-3)" "unprognostic (2.85e-1)" "unprognostic (1.86e-2)" "unprognostic (1.01e-3)" "unprognostic (7.41e-2)" "unprognostic (1.09e-1)" "unprognostic (3.55e-1)" "unprognostic (1.60e-1)" "unprognostic (1.18e-1)" ITLN2 HL-2 ENSG00000158764 "Intelectin 2" Q8WWU7 1 160945025-160954809 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 35 "intestine: 384.4" "Cell type enriched" "Detected in some" 49 "Paneth cells: 1902.8" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Rectum Adenocarcinoma (TCGA): 13.3;Testicular Germ Cell Tumor (TCGA): 7.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 5.4;pancreatic cancer: 2.3;testis cancer: 3.5" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 1, Prostate - Prostate glandular cells" "Low region specificity" "Detected in many" "HPA006683, HPA067326" Enhanced "Secreted to digestive system" "No annotated function" NA NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 15: Non-specific - Protein processing" 50 "HPA006683: , HPA067326: " "unprognostic (2.85e-1)" "unprognostic (5.12e-2)" "unprognostic (4.22e-1)" "unprognostic (2.57e-3)" "unprognostic (3.10e-1)" "unprognostic (8.97e-3)" "unprognostic (1.06e-1)" "unprognostic (3.41e-1)" "unprognostic (4.54e-2)" "unprognostic (2.45e-2)" "unprognostic (2.48e-1)" "unprognostic (2.45e-1)" ITM2A "BRICD2A, E25A" ENSG00000078596 "Integral membrane protein 2A" O43736 X 79360384-79367667 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 300.7" "Cell type enhanced" "Detected in many" "Breast lactating cells: 102.8;Breast myoepithelial cells: 196.3;Fibroblasts: 192.1;Lacrimal acinar cells: 191.1;Leydig cells: 169.5;Mast cells: 160.3;Müller glia: 180.0;Ovarian stromal cells: 200.7;Peritubular myoid cells: 110.5;Platelets: 145.1;T-cells: 195.2;Vascular endothelial cells: 294.1" "Cell type enriched" "Detected in many" 15 "endothelial cell: 909.6" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 84.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 173.0;eosinophil: 88.6;gdT-cell: 107.2;MAIT T-cell: 79.4;memory CD4 T-cell: 205.2;memory CD8 T-cell: 170.3;naive CD4 T-cell: 217.2;naive CD8 T-cell: 101.8;NK-cell: 130.9;T-reg: 168.4" "Group enriched" "Detected in all" 7 "granulocytes: 173.0;NK-cells: 130.9;T-cells: 217.2" "Group enriched" "Detected in many" 8 "Bone cancer: 184.6;Leukemia: 155.6;Myeloma: 57.1;prostate cancer: 105.4" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000296 Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 80: Thymus - Adaptive immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 59: Leukemia - T-cell receptor" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 9 Vesicles "Golgi apparatus, Plasma membrane" "HPA000296: " "unprognostic (6.25e-2)" "unprognostic (1.55e-2)" "unprognostic (3.09e-1)" "unprognostic (9.18e-3)" "unprognostic (5.39e-2)" "unprognostic (3.85e-2)" "unprognostic (4.51e-2)" "unprognostic (1.15e-2)" "unprognostic (5.13e-3)" "unprognostic (2.40e-3)" "potential prognostic favorable (2.00e-5)" "unprognostic (2.06e-2)" "unprognostic (4.67e-3)" "potential prognostic favorable (8.70e-5)" "unprognostic (3.96e-2)" "unprognostic (6.27e-2)" "unprognostic (8.20e-2)" "unprognostic (9.57e-2)" "unprognostic (2.72e-2)" "unprognostic (1.37e-1)" "unprognostic (1.94e-1)" "unprognostic (8.97e-3)" "unprognostic (1.67e-1)" "unprognostic (5.69e-2)" "unprognostic (1.51e-1)" "unprognostic (6.87e-2)" "unprognostic (5.17e-1)" "unprognostic (8.97e-2)" "unprognostic (1.04e-1)" "unprognostic (9.80e-2)" "unprognostic (2.10e-1)" ITM2B "BRI, BRI2, BRICD2B, E25B, E3-16" ENSG00000136156 "Integral membrane protein 2B" Q9Y287 13 48232612-48270357 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Amyloidosis, Deafness, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epididymal principal cells: 6027.5;Extravillous trophoblasts: 3846.7;Hofbauer cells: 3696.1;Neutrophils: 4596.9;Platelets: 5581.7" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Renal Papillary Cell Carcinoma (TCGA): 1616.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 4399.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 4399.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029292, HPA071992" Enhanced Enhanced "Golgi apparatus,Vesicles" "Secreted to blood" "No annotated function" NA NA 2100000 "Cluster 21: Neutrophils - Unknown function" "Cluster 72: Kidney - Transmembrane transport" "Cluster 21: Non-specific - Metabolism" "Cluster 15: Kidney cancer - Membrane components" "Cluster 24: Neutrophils - Innate immunity signal integration" 34 "Golgi apparatus, Vesicles" "HPA029292: , HPA071992: " "potential prognostic favorable (2.65e-4)" "unprognostic (2.09e-2)" "unprognostic (2.43e-2)" "unprognostic (2.65e-3)" "unprognostic (2.44e-1)" "unprognostic (9.29e-3)" "unprognostic (7.25e-2)" "unprognostic (2.25e-1)" "unprognostic (2.57e-1)" "unprognostic (2.46e-1)" "validated prognostic favorable (1.36e-6)" "validated prognostic favorable (1.77e-4)" "potential prognostic favorable (1.83e-4)" "unprognostic (7.21e-2)" "unprognostic (2.53e-1)" "unprognostic (1.15e-2)" "unprognostic (1.42e-1)" "unprognostic (2.04e-1)" "unprognostic (2.51e-2)" "unprognostic (8.22e-2)" "unprognostic (4.63e-3)" "unprognostic (1.98e-2)" "unprognostic (7.94e-2)" "unprognostic (1.21e-1)" "unprognostic (1.04e-3)" "unprognostic (8.80e-2)" "unprognostic (2.79e-2)" "unprognostic (2.74e-3)" "unprognostic (1.27e-1)" "unprognostic (1.50e-1)" "unprognostic (1.82e-1)" ITM2C "BRI3, BRICD2C, E25, hRPC.1050_D_4, ITM3" ENSG00000135916 "Integral membrane protein 2C" Q9NQX7 2 230864639-230879248 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1020.9;intestine: 662.7" "Cell type enhanced" "Detected in many" "Colonocytes: 2242.8;Enteric stem cells: 635.1;Enteric transient amplifying cells: 790.7;Enterocytes: 607.9;Goblet cells: 863.7;pDCs: 836.4;Plasma cells: 656.7;Tuft cells: 507.2" "Cell type enhanced" "Detected in all" "pericyte: 380.7" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 1036.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 8 "plasmacytoid DC: 2468.4" "Lineage enriched" "Detected in all" 8 "dendritic cells: 2468.4" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Pituitary gland - Lactotropes, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 6400 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 78: Brain - Neuronal signaling" "Cluster 46: Brainstem - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 3 "unprognostic (4.93e-2)" "unprognostic (6.84e-3)" "unprognostic (3.33e-1)" "unprognostic (4.04e-2)" "unprognostic (1.48e-2)" "unprognostic (6.78e-2)" "unprognostic (2.37e-1)" "unprognostic (2.47e-2)" "unprognostic (3.15e-1)" "unprognostic (1.14e-1)" "potential prognostic favorable (2.16e-4)" "unprognostic (1.71e-1)" "unprognostic (2.66e-1)" "unprognostic (8.13e-2)" "unprognostic (7.48e-2)" "unprognostic (5.75e-2)" "unprognostic (1.92e-1)" "unprognostic (1.17e-2)" "unprognostic (6.55e-2)" "unprognostic (3.93e-2)" "unprognostic (8.28e-2)" "unprognostic (7.66e-2)" "unprognostic (7.15e-2)" "unprognostic (4.34e-2)" "unprognostic (1.01e-1)" "potential prognostic unfavorable (2.88e-4)" "unprognostic (2.26e-2)" "unprognostic (1.39e-2)" "unprognostic (4.28e-2)" "unprognostic (4.28e-2)" "unprognostic (2.02e-1)" ITPA "C20orf37, dJ794I6.3, HLC14-06-P" ENSG00000125877 "Inosine triphosphatase" Q9BY32 20 3208868-3223870 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022824, HPA073963" Approved Supported Nucleoplasm,Cytosol NA NA 50000 "Cluster 13: Non-specific - Mitochondria" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 97: Non-specific - Cellular respiration" 6 "Nucleoplasm, Cytosol" "HPA022824: , HPA073963: " "unprognostic (4.80e-2)" "unprognostic (3.13e-1)" "unprognostic (4.56e-2)" "unprognostic (7.69e-3)" "unprognostic (2.57e-1)" "unprognostic (6.52e-2)" "unprognostic (1.02e-1)" "unprognostic (2.22e-2)" "unprognostic (6.60e-2)" "unprognostic (2.24e-1)" "unprognostic (2.93e-3)" "potential prognostic unfavorable (6.41e-4)" "unprognostic (5.68e-2)" "validated prognostic unfavorable (4.24e-6)" "validated prognostic unfavorable (6.03e-5)" "unprognostic (1.82e-2)" "unprognostic (4.90e-2)" "unprognostic (6.64e-3)" "unprognostic (1.15e-1)" "unprognostic (1.11e-1)" "unprognostic (7.61e-2)" "unprognostic (6.95e-2)" "unprognostic (3.73e-1)" "unprognostic (4.97e-1)" "unprognostic (2.16e-1)" "unprognostic (2.94e-2)" "unprognostic (1.57e-1)" "unprognostic (9.68e-2)" "unprognostic (2.58e-1)" "unprognostic (1.99e-1)" "unprognostic (9.75e-2)" ITPK1 ENSG00000100605 "Inositol-tetrakisphosphate 1-kinase" Q13572 14 92936914-93116320 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Isomerase, Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 190.5" "Cell type enhanced" "Detected in some" "Astrocytes: 64.8;Bergmann glia: 162.8;Brain excitatory neurons: 46.6;Brain inhibitory neurons: 42.4;Choroid plexus epithelial cells: 81.9;Distal convoluted tubule cells: 50.5;Loop of henle epithelial cells: 62.7;Microglia: 80.5;Oligodendrocyte progenitor cells: 54.6;Oligodendrocytes: 89.0;Other brain neurons: 38.6;Papillary tip epithelial cells: 56.5;Proximal tubule cells: 64.1;Renal collecting duct intercalated cells: 126.5;Renal collecting duct principal cells: 183.9;Renal connecting tubule cells: 89.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 43.1" "Group enriched" "Detected in all" 5 "granulocytes: 43.1;monocytes: 26.1" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055230 Approved Approved Mitochondria NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 102: Non-specific - Mixed function" 1 Mitochondria "HPA055230: " "unprognostic (8.46e-2)" "unprognostic (5.11e-2)" "unprognostic (4.49e-2)" "unprognostic (5.06e-2)" "unprognostic (7.98e-2)" "unprognostic (5.00e-2)" "unprognostic (4.37e-1)" "unprognostic (2.50e-1)" "unprognostic (1.08e-1)" "unprognostic (1.77e-1)" "potential prognostic favorable (3.27e-5)" "unprognostic (4.36e-2)" "unprognostic (2.38e-2)" "unprognostic (3.46e-2)" "unprognostic (1.20e-1)" "unprognostic (6.34e-2)" "unprognostic (2.01e-1)" "unprognostic (8.44e-2)" "unprognostic (2.69e-1)" "unprognostic (1.67e-1)" "unprognostic (1.22e-1)" "unprognostic (2.14e-1)" "unprognostic (9.70e-2)" "unprognostic (1.40e-1)" "unprognostic (1.52e-1)" "unprognostic (2.65e-1)" "unprognostic (2.44e-1)" "unprognostic (7.50e-2)" "unprognostic (2.75e-1)" "unprognostic (2.15e-1)" "unprognostic (7.88e-2)" ITPKA "IP3-3KA, IP3KA" ENSG00000137825 "Inositol-trisphosphate 3-kinase A" P23677 15 41493393-41503551 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 57.3;intestine: 17.0" "Cell type enriched" "Detected in many" 4 "Late spermatids: 300.6" "Cell type enhanced" "Detected in many" "miscellaneous: 32.8;upper-layer intratelencephalic: 53.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "MAIT T-cell: 1.4" "Lineage enriched" "Detected in single" 11 "T-cells: 1.4" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Heart muscle - Cardiomyocytes, Minor Salivary Gland - Minor salivary gland ductal cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "amygdala: 11.2;basal ganglia: 44.1;cerebral cortex: 33.5;hippocampal formation: 29.2" HPA040454 Enhanced Approved NA No "Cluster 78: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" "HPA040454: " "unprognostic (1.13e-1)" "unprognostic (1.50e-1)" "unprognostic (3.63e-1)" "unprognostic (5.29e-2)" "unprognostic (2.33e-1)" "unprognostic (2.24e-1)" "potential prognostic unfavorable (5.71e-4)" "unprognostic (7.72e-2)" "unprognostic (1.32e-2)" "unprognostic (1.92e-3)" "potential prognostic unfavorable (3.92e-13)" "unprognostic (1.50e-2)" "unprognostic (3.81e-2)" "unprognostic (1.95e-3)" "unprognostic (2.87e-3)" "unprognostic (6.42e-2)" "unprognostic (1.40e-1)" "unprognostic (2.40e-1)" "unprognostic (1.02e-1)" "unprognostic (3.88e-1)" "unprognostic (5.79e-2)" "unprognostic (6.87e-2)" "unprognostic (2.17e-1)" "unprognostic (3.30e-1)" ITPKB "IP3-3KB, IP3KB" ENSG00000143772 "Inositol-trisphosphate 3-kinase B" P27987 1 226631690-226739323 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 98.8;choroid plexus: 90.2" "Cell type enhanced" "Detected in many" "Astrocytes: 373.3;Bergmann glia: 212.0;Choroid plexus epithelial cells: 888.6;Distal convoluted tubule cells: 420.3;Ependymal cells: 306.7;Mast cells: 175.9;T-cells: 190.0" "Cell type enhanced" "Detected in many" "astrocyte: 600.5;choroid plexus epithelial cell: 637.3" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 87.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "skin cancer: 44.9" "Minor Salivary Gland - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030273, HPA072923" Enhanced Approved Nucleoplasm NA NA 11000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 9 Nucleoplasm "HPA030273: , HPA072923: " "unprognostic (2.57e-3)" "unprognostic (1.04e-1)" "unprognostic (2.24e-2)" "unprognostic (2.55e-3)" "unprognostic (2.46e-1)" "unprognostic (1.84e-2)" "unprognostic (2.25e-1)" "unprognostic (3.34e-3)" "unprognostic (5.52e-3)" "unprognostic (1.15e-1)" "validated prognostic favorable (7.25e-6)" "validated prognostic favorable (2.37e-4)" "unprognostic (2.75e-2)" "unprognostic (7.21e-2)" "unprognostic (1.29e-2)" "unprognostic (1.16e-2)" "unprognostic (1.50e-1)" "unprognostic (4.16e-2)" "unprognostic (1.93e-3)" "unprognostic (4.82e-2)" "unprognostic (6.74e-2)" "unprognostic (8.45e-2)" "unprognostic (2.76e-1)" "unprognostic (5.91e-2)" "unprognostic (1.86e-2)" "unprognostic (5.68e-3)" "unprognostic (4.39e-1)" "unprognostic (1.55e-2)" "unprognostic (1.04e-1)" "unprognostic (2.41e-2)" "unprognostic (3.10e-1)" ITPKC "IP3-3KC, IP3KC" ENSG00000086544 "Inositol-trisphosphate 3-kinase C" Q96DU7 19 40717112-40740860 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 94.0" "Cell type enhanced" "Detected in many" "Epididymal basal cells: 571.2;Esophageal apical cells: 1076.2;Esophageal suprabasal cells: 758.4;Fallopian secretory cells: 501.3;Ocular epithelial cells: 995.4;Prostatic hillock cells: 473.9;Respiratory basal cells: 736.5;Salivary acinar cells: 598.1;Suprabasal keratinocytes: 676.5;Urothelial cells: 916.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose visceral - Neutrophils, Colon - Neutrophils, Liver - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050760, HPA053003" Approved Supported "Nuclear speckles" No No "Cluster 33: Non-specific - ATP binding" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 2 "Nuclear speckles" "HPA050760: , HPA053003: " "unprognostic (7.52e-2)" "unprognostic (1.45e-1)" "unprognostic (1.64e-1)" "unprognostic (1.69e-1)" "unprognostic (7.08e-2)" "unprognostic (1.54e-2)" "unprognostic (1.95e-2)" "unprognostic (1.63e-1)" "unprognostic (1.97e-1)" "unprognostic (7.30e-3)" "unprognostic (6.42e-2)" "unprognostic (9.32e-3)" "unprognostic (1.98e-1)" "unprognostic (5.41e-2)" "unprognostic (2.67e-1)" "unprognostic (2.32e-3)" "unprognostic (7.91e-2)" "unprognostic (2.15e-1)" "unprognostic (2.82e-2)" "potential prognostic unfavorable (9.68e-4)" "unprognostic (6.74e-2)" "potential prognostic unfavorable (8.55e-4)" "unprognostic (1.46e-3)" "unprognostic (1.73e-1)" "unprognostic (6.74e-2)" "unprognostic (1.34e-3)" "unprognostic (4.04e-1)" "unprognostic (3.13e-1)" "unprognostic (7.76e-2)" "unprognostic (6.61e-2)" "unprognostic (1.53e-3)" ITPR1 "ACV, Insp3r1, IP3R1, PPP1R94, SCA15, SCA16, SCA29" ENSG00000150995 "Inositol 1,4,5-trisphosphate receptor type 1" Q14643 3 4493345-4847506 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Intellectual disability, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 556.3;Choroid plexus epithelial cells: 718.2;Distal convoluted tubule cells: 893.4;Gonadotrophs: 1021.3;Pituitary stem cells: 648.3;Retinal pigment epithelial cells: 524.3;Salivary myoepithelial cells: 586.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 27.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Prostate - Smooth muscle cells, Thyroid gland - Thyroid glandular cells" "Region enhanced" "Detected in all" "cerebellum: 697.2" "Region enhanced" "Detected in all" "cerebellum: 273.5" "HPA014765, HPA016487" Approved Uncertain Vesicles NA NA "Cluster 32: Basophils - Transcription" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 2: Neurons - Nucleosome" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" 28 Vesicles "HPA014765: , HPA016487: " "unprognostic (3.34e-1)" "unprognostic (8.92e-2)" "unprognostic (5.14e-1)" "potential prognostic unfavorable (5.26e-5)" "unprognostic (1.46e-1)" "unprognostic (1.49e-1)" "unprognostic (1.91e-1)" "unprognostic (1.07e-1)" "unprognostic (2.28e-1)" "unprognostic (1.43e-2)" "potential prognostic favorable (2.27e-4)" "unprognostic (1.68e-2)" "unprognostic (2.18e-1)" "unprognostic (8.54e-2)" "unprognostic (3.30e-3)" "unprognostic (2.16e-1)" "unprognostic (1.36e-1)" "unprognostic (3.93e-2)" "unprognostic (2.58e-2)" "unprognostic (6.76e-3)" "unprognostic (5.64e-2)" "unprognostic (1.00e-1)" "unprognostic (5.84e-2)" "unprognostic (2.14e-1)" "unprognostic (1.12e-1)" "unprognostic (1.51e-2)" "unprognostic (6.37e-2)" "unprognostic (6.61e-2)" "unprognostic (1.71e-1)" "unprognostic (2.32e-3)" "unprognostic (1.52e-1)" ITPR2 "CFAP48, IP3R2" ENSG00000123104 "Inositol 1,4,5-trisphosphate receptor type 2" Q14571 12 26335352-26833194 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 41.5" "Cell type enhanced" "Detected in many" "Microglia: 2534.3;Renal collecting duct intercalated cells: 1406.5;Respiratory ionocytes: 1376.7;Salivary ionocytes: 3810.7;Tuft cells: 1556.3" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 3257.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 32.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059144, HPA062260" Uncertain Approved "Nucleoplasm,Endoplasmic reticulum,Mid piece,Principal piece,End piece" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 44: Non-specific - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 10 "Endoplasmic reticulum, Mid piece" "Nucleoplasm, Principal piece, End piece" "HPA059144: , HPA062260: " "unprognostic (2.71e-2)" "unprognostic (2.07e-2)" "unprognostic (6.69e-2)" "unprognostic (1.36e-1)" "unprognostic (2.23e-1)" "unprognostic (4.57e-2)" "unprognostic (1.89e-1)" "unprognostic (7.44e-2)" "unprognostic (8.57e-2)" "unprognostic (9.63e-2)" "potential prognostic favorable (4.77e-4)" "unprognostic (1.00e-2)" "unprognostic (1.10e-1)" "unprognostic (2.63e-3)" "unprognostic (9.96e-2)" "unprognostic (3.10e-3)" "unprognostic (1.20e-1)" "unprognostic (8.83e-3)" "unprognostic (4.36e-1)" "unprognostic (1.81e-2)" "unprognostic (1.14e-1)" "unprognostic (2.46e-2)" "unprognostic (4.77e-2)" "unprognostic (2.23e-1)" "unprognostic (1.74e-1)" "unprognostic (9.52e-2)" "unprognostic (5.60e-1)" "unprognostic (1.75e-1)" "unprognostic (1.06e-1)" "unprognostic (7.68e-2)" "unprognostic (3.16e-2)" ITPR3 IP3R3 ENSG00000096433 "Inositol 1,4,5-trisphosphate receptor type 3" Q14573 6 33620365-33696574 "Human disease related genes, Plasma proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Ligand-gated ion channel, Receptor" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 120.5;Alveolar cells type 2: 135.6;Early spermatids: 175.5;Foveolar cells: 220.8;Late spermatids: 339.9;Sertoli cells: 176.3" "Group enriched" "Detected in many" 4 "endothelial cell: 100.5;fibroblast: 28.7;leukocyte: 41.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Spleen - Endothelial cells, Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA003915, HPA064704" Approved Approved Vesicles,Cytosol No Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 77: Intestine - Digestion" "Cluster 47: Endothelial cells - Vasculature" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 68: Foveolar cells - Mucosal defense" 37 Vesicles Cytosol "HPA003915: , HPA064704: " "unprognostic (7.10e-2)" "unprognostic (9.17e-2)" "unprognostic (1.70e-1)" "unprognostic (1.20e-2)" "unprognostic (2.46e-1)" "unprognostic (2.86e-2)" "unprognostic (1.66e-2)" "unprognostic (7.67e-2)" "unprognostic (1.77e-1)" "unprognostic (1.08e-2)" "unprognostic (1.07e-2)" "unprognostic (1.19e-1)" "unprognostic (3.37e-1)" "unprognostic (2.38e-2)" "unprognostic (2.87e-2)" "unprognostic (1.48e-1)" "unprognostic (4.31e-1)" "unprognostic (1.45e-1)" "unprognostic (1.36e-2)" "unprognostic (6.85e-2)" "unprognostic (2.56e-1)" "unprognostic (5.38e-3)" "unprognostic (9.28e-3)" "unprognostic (5.26e-1)" "unprognostic (1.76e-3)" "unprognostic (3.43e-2)" "unprognostic (2.39e-1)" "unprognostic (9.92e-2)" "unprognostic (1.67e-1)" "unprognostic (4.58e-2)" "unprognostic (6.07e-2)" ITPRID1 "CCDC129, FLJ38344" ENSG00000180347 "ITPR interacting domain containing 1" Q6ZRS4 7 31514090-31656504 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.4;salivary gland: 4.2;skin 1: 1.9" "Cell type enriched" "Detected in many" 8 "Tuft cells: 1913.7" "Cell type enriched" "Detected in many" 4 "astrocyte: 136.1" "Cancer enhanced" "Detected in single" "Lung Adenocarcinoma (TCGA): 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Eccrine sweat gland cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" "Region enriched" "Detected in many" 4 "cerebellum: 45.9" HPA024103 Uncertain Uncertain Nucleoplasm NA NA "Cluster 60: Stomach - Digestion" "Cluster 19: Astrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 95: Tuft cells - Chemosensory signaling" Nucleoplasm "HPA024103: " "unprognostic (1.27e-1)" "unprognostic (2.97e-2)" "potential prognostic favorable (6.97e-4)" "unprognostic (1.09e-2)" "unprognostic (1.05e-1)" ITPRID2 "CS-1, KIAA1927, KRAP, SPAG13, SSFA2" ENSG00000138434 "ITPR interacting domain containing 2" P28290 2 181891730-181930738 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 165.7" "Cell type enhanced" "Detected in many" "Colonocytes: 340.5;Platelets: 286.5;Salivary ionocytes: 425.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "dendritic cells: 2.7;granulocytes: 6.1;monocytes: 5.1" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034665, HPA039989" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 8: Pancreas - Proteolysis" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 28 "Plasma membrane, Cytosol" Nucleoplasm "HPA034665: , HPA039989: " "unprognostic (7.70e-2)" "unprognostic (3.40e-2)" "unprognostic (2.29e-2)" "unprognostic (1.87e-1)" "unprognostic (1.19e-1)" "unprognostic (1.32e-1)" "potential prognostic unfavorable (5.11e-5)" "unprognostic (7.39e-2)" "unprognostic (7.39e-2)" "validated prognostic favorable (1.66e-9)" "validated prognostic favorable (8.40e-4)" "unprognostic (1.93e-1)" "unprognostic (2.80e-1)" "unprognostic (3.00e-2)" "unprognostic (7.26e-2)" "unprognostic (1.58e-1)" "unprognostic (1.81e-1)" "unprognostic (1.43e-2)" "unprognostic (1.55e-1)" "potential prognostic unfavorable (2.31e-4)" "unprognostic (1.13e-2)" "unprognostic (4.15e-2)" "unprognostic (4.76e-1)" "unprognostic (1.49e-2)" "unprognostic (1.35e-1)" "unprognostic (6.67e-2)" "unprognostic (1.89e-1)" "unprognostic (1.25e-1)" "unprognostic (4.22e-1)" ITPRIP "bA127L20.2, DANGER, KIAA1754" ENSG00000148841 "Inositol 1,4,5-trisphosphate receptor interacting protein" Q8IWB1 10 104309698-104338465 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 192.1" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 239.3;Esophageal basal cells: 207.5;Esophageal suprabasal cells: 236.7;monocytes: 144.3;Neutrophil progenitors: 169.8;Neutrophils: 801.9;Suprabasal keratinocytes: 144.4;Vascular endothelial cells: 138.9" "Group enriched" "Detected in many" 4 "central nervous system macrophage: 27.5;endothelial cell: 51.8;fibroblast: 17.6;leukocyte: 38.6;pericyte: 13.3;vascular associated smooth muscle cell: 38.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 30.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA043626 Uncertain Vesicles NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 15: Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 72: Neuronal - Signal transduction" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 13 Vesicles "HPA043626: " "unprognostic (9.39e-3)" "unprognostic (1.94e-1)" "unprognostic (2.77e-1)" "unprognostic (9.79e-2)" "unprognostic (8.86e-2)" "unprognostic (9.97e-2)" "unprognostic (7.43e-2)" "unprognostic (1.31e-2)" "unprognostic (2.41e-1)" "unprognostic (6.40e-2)" "validated prognostic favorable (2.58e-5)" "validated prognostic favorable (4.14e-4)" "unprognostic (3.48e-2)" "unprognostic (1.02e-1)" "unprognostic (2.91e-3)" "unprognostic (1.94e-2)" "unprognostic (1.14e-2)" "unprognostic (5.63e-2)" "unprognostic (5.22e-2)" "unprognostic (4.01e-2)" "unprognostic (1.51e-1)" "unprognostic (1.19e-2)" "unprognostic (5.40e-2)" "unprognostic (1.58e-1)" "unprognostic (2.50e-1)" "potential prognostic favorable (1.76e-4)" "unprognostic (1.95e-1)" "potential prognostic unfavorable (5.84e-4)" "unprognostic (2.00e-2)" "unprognostic (4.41e-2)" "unprognostic (3.37e-1)" ITPRIPL1 KIAA1754L ENSG00000198885 "ITPRIP like 1" Q6GPH6 2 96325317-96330517 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 26.1" "Group enriched" "Detected in many" 7 "Early spermatids: 187.8;Late primary spermatocytes: 80.4;Late spermatids: 241.7" "Group enriched" "Detected in some" 4 "central nervous system macrophage: 4.7;leukocyte: 12.8;oligodendrocyte precursor cell: 3.7;upper rhombic lip: 4.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 12.9" "Lineage enriched" "Detected in many" 5 "T-cells: 12.9" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Minor Salivary Gland - Minor salivary gland ductal cells, Prostate - Prostate basal glandular cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 6 "unprognostic (2.51e-1)" "unprognostic (3.92e-3)" "unprognostic (1.07e-1)" "unprognostic (9.03e-2)" "unprognostic (3.31e-1)" "unprognostic (3.88e-1)" "unprognostic (1.22e-1)" "unprognostic (6.67e-2)" "unprognostic (7.66e-3)" "unprognostic (1.22e-1)" "unprognostic (3.10e-1)" "unprognostic (1.97e-1)" "unprognostic (3.99e-2)" "unprognostic (6.29e-2)" "unprognostic (1.85e-1)" "unprognostic (1.72e-2)" "unprognostic (2.48e-1)" "potential prognostic unfavorable (3.93e-4)" "unprognostic (1.66e-1)" "unprognostic (1.49e-1)" "unprognostic (1.01e-2)" "unprognostic (4.87e-2)" "unprognostic (1.12e-1)" "unprognostic (2.18e-1)" "unprognostic (2.32e-1)" ITPRIPL2 "FLJ22994, LOC162073, MGC126798, MGC126800" ENSG00000205730 "ITPRIP like 2" Q3MIP1 16 19113932-19121629 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Salivary ionocytes: 1.4;Thymic myoid cells: 1.4" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042011 Approved Centrosome NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 82: Dendritic cells - Antigen presentation" 4 Centrosome "HPA042011: " "unprognostic (9.41e-2)" "unprognostic (1.13e-2)" "unprognostic (8.61e-2)" "unprognostic (1.72e-3)" "unprognostic (6.72e-2)" "unprognostic (2.42e-1)" "unprognostic (4.70e-2)" "unprognostic (3.92e-2)" "unprognostic (2.26e-1)" "unprognostic (2.97e-1)" "unprognostic (1.86e-1)" "unprognostic (1.56e-1)" "unprognostic (1.75e-1)" "unprognostic (8.88e-3)" "unprognostic (9.18e-2)" "unprognostic (8.76e-2)" "unprognostic (1.84e-2)" "unprognostic (2.20e-2)" "unprognostic (1.51e-1)" "unprognostic (2.04e-2)" "unprognostic (1.12e-3)" "unprognostic (1.66e-2)" "unprognostic (3.43e-3)" "unprognostic (5.89e-2)" "unprognostic (7.10e-2)" "unprognostic (1.28e-1)" "unprognostic (5.58e-2)" "unprognostic (1.51e-1)" "unprognostic (1.91e-1)" "unprognostic (8.75e-2)" "unprognostic (1.26e-1)" ITSN1 "ITSN, MGC134948, MGC134949, SH3D1A, SH3P17" ENSG00000205726 "Intersectin 1" Q15811 21 33642400-33899861 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Endocytosis, Exocytosis, Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 928.3;Macrophages: 452.1;Rod photoreceptor cells: 517.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 5.5;non-classical monocyte: 5.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018007 Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 23: Choroid plexus - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 68 "Plasma membrane" Nucleoplasm "HPA018007: " "unprognostic (1.02e-1)" "unprognostic (4.43e-2)" "unprognostic (1.13e-3)" "unprognostic (2.11e-2)" "unprognostic (1.62e-1)" "unprognostic (5.71e-2)" "unprognostic (1.42e-1)" "unprognostic (1.51e-1)" "unprognostic (9.98e-2)" "unprognostic (2.27e-2)" "unprognostic (5.71e-2)" "unprognostic (1.12e-1)" "unprognostic (2.24e-2)" "unprognostic (4.19e-2)" "unprognostic (3.16e-2)" "unprognostic (4.52e-3)" "unprognostic (7.80e-3)" "unprognostic (8.97e-2)" "unprognostic (1.61e-1)" "unprognostic (4.69e-2)" "unprognostic (7.79e-3)" "unprognostic (7.66e-2)" "unprognostic (4.88e-2)" "unprognostic (1.88e-2)" "unprognostic (8.27e-2)" "unprognostic (3.17e-3)" "unprognostic (4.58e-2)" "unprognostic (1.36e-2)" "unprognostic (1.89e-1)" "unprognostic (2.28e-3)" "unprognostic (1.69e-1)" ITSN2 "KIAA1256, PRO2015, SH3D1B, SH3P18, SWA, SWAP" ENSG00000198399 "Intersectin 2" Q9NZM3 2 24202864-24360536 "Predicted intracellular proteins" "Differentiation, Endocytosis, Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1103.0;Neutrophils: 746.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036475 Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 11: White matter - Signal transduction" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 20 "Vesicles, Plasma membrane" "HPA036475: " "unprognostic (5.39e-3)" "unprognostic (3.43e-1)" "unprognostic (6.37e-2)" "unprognostic (1.53e-2)" "unprognostic (3.97e-1)" "unprognostic (1.81e-2)" "unprognostic (3.07e-1)" "unprognostic (2.32e-1)" "unprognostic (1.43e-3)" "unprognostic (1.83e-3)" "potential prognostic favorable (4.64e-6)" "unprognostic (3.83e-3)" "unprognostic (6.02e-2)" "unprognostic (2.66e-2)" "unprognostic (1.31e-1)" "unprognostic (8.37e-2)" "unprognostic (2.07e-1)" "unprognostic (1.02e-1)" "unprognostic (2.37e-1)" "unprognostic (1.80e-1)" "unprognostic (1.79e-1)" "unprognostic (5.79e-3)" "unprognostic (1.07e-2)" "unprognostic (1.04e-1)" "unprognostic (1.04e-2)" "unprognostic (5.83e-2)" "unprognostic (1.46e-1)" "unprognostic (1.66e-1)" "unprognostic (8.74e-2)" "unprognostic (1.15e-1)" "unprognostic (6.00e-2)" IVD "ACAD2, IVDH" ENSG00000128928 "Isovaleryl-CoA dehydrogenase" P26440 15 40405485-40435947 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 170.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Prostate - Prostate glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041391, HPA044250" Enhanced Supported Nucleoplasm,Mitochondria NA NA 5600 "Cluster 13: Non-specific - Mitochondria" "Cluster 76: Non-specific - Metabolism" "Cluster 46: Brainstem - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 19 Mitochondria Nucleoplasm "HPA041391: , HPA044250: " "unprognostic (4.87e-3)" "unprognostic (4.27e-2)" "unprognostic (3.32e-1)" "unprognostic (3.10e-2)" "unprognostic (1.18e-1)" "unprognostic (2.28e-1)" "unprognostic (4.60e-2)" "unprognostic (4.95e-2)" "unprognostic (7.79e-2)" "unprognostic (1.75e-1)" "validated prognostic favorable (4.85e-6)" "validated prognostic favorable (1.89e-7)" "unprognostic (8.80e-3)" "potential prognostic favorable (2.01e-4)" "unprognostic (3.58e-2)" "potential prognostic favorable (2.25e-4)" "unprognostic (1.94e-1)" "unprognostic (1.59e-1)" "unprognostic (6.36e-2)" "unprognostic (2.39e-2)" "unprognostic (1.36e-1)" "unprognostic (8.04e-2)" "unprognostic (2.94e-1)" "unprognostic (9.26e-2)" "unprognostic (5.28e-2)" "unprognostic (2.05e-1)" "unprognostic (1.89e-1)" "unprognostic (1.33e-1)" "unprognostic (2.71e-1)" "unprognostic (5.53e-2)" "unprognostic (3.04e-2)" IVL ENSG00000163207 Involucrin P07476 1 152908546-152911886 "Plasma proteins, Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "cervix: 195.7;esophagus: 294.3;salivary gland: 84.6;skin 1: 156.4;vagina: 223.1" "Group enriched" "Detected in some" 4 "Esophageal apical cells: 3166.6;Esophageal suprabasal cells: 1049.9" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Bladder Urothelial Carcinoma (TCGA): 109.0;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 100.2;Head and Neck Squamous Cell Carcinoma (TCGA): 234.7;Skin Cutaneous Melanoma (TCGA): 112.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder cancer: 46.5;head and neck cancer: 43.5" "Prostate - Urothelial cells" "Not detected" "Not detected" "CAB002243, HPA055211" Enhanced Supported "Nuclear bodies,Centrosome,Cytosol" NA NA 2900000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 33 Cytosol "Nuclear bodies, Centrosome" "CAB002243: , HPA055211: " "unprognostic (1.13e-1)" "unprognostic (4.38e-1)" "unprognostic (1.11e-1)" "unprognostic (1.57e-2)" "unprognostic (1.82e-1)" "unprognostic (6.35e-2)" "unprognostic (1.47e-1)" "unprognostic (1.96e-2)" "unprognostic (3.05e-2)" "unprognostic (1.07e-2)" "unprognostic (2.49e-1)" "unprognostic (2.69e-1)" "unprognostic (3.57e-1)" "unprognostic (1.21e-2)" "unprognostic (8.84e-2)" IVNS1ABP "ARA3, HSPC068, KIAA0850, KLHL39, ND1, NS-1, NS1-BP" ENSG00000116679 "Influenza virus NS1A binding protein" Q9Y6Y0 1 185296388-185317273 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "bone marrow: 427.4" "Cell type enhanced" "Detected in all" "Distal convoluted tubule cells: 530.8;Neutrophil progenitors: 839.6;Neutrophils: 3315.1" "Cell type enhanced" "Detected in all" "endothelial cell: 220.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary gland ductal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003405 Approved Supported Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 21 Cytosol "HPA003405: " "unprognostic (2.09e-2)" "unprognostic (1.31e-2)" "unprognostic (2.59e-1)" "unprognostic (6.47e-2)" "unprognostic (1.38e-1)" "unprognostic (2.07e-2)" "unprognostic (8.65e-2)" "unprognostic (2.65e-1)" "unprognostic (5.94e-2)" "unprognostic (3.13e-2)" "validated prognostic favorable (5.45e-9)" "validated prognostic favorable (5.65e-6)" "unprognostic (7.95e-2)" "potential prognostic unfavorable (6.99e-4)" "unprognostic (3.58e-1)" "unprognostic (8.80e-2)" "unprognostic (5.48e-3)" "unprognostic (3.12e-1)" "unprognostic (6.43e-2)" "unprognostic (1.90e-1)" "unprognostic (1.54e-1)" "unprognostic (1.05e-2)" "unprognostic (3.78e-1)" "unprognostic (5.81e-2)" "unprognostic (3.88e-1)" "unprognostic (5.67e-2)" "unprognostic (3.69e-1)" "unprognostic (1.27e-1)" "unprognostic (1.79e-1)" "unprognostic (3.11e-2)" "unprognostic (2.98e-1)" IWS1 "DKFZp761G0123, FLJ10006, FLJ14655, FLJ32319" ENSG00000163166 "Interacts with SUPT6H, CTD assembly factor 1" Q96ST2 2 127436207-127526886 "Predicted intracellular proteins" "mRNA processing, mRNA splicing, mRNA transport, Transcription, Transcription regulation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035719, HPA061866" Supported Enhanced Nucleoplasm NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 51: Secretory epithelial cells - Mixed function" 18 Nucleoplasm "HPA035719: , HPA061866: " "unprognostic (4.30e-1)" "unprognostic (1.56e-1)" "unprognostic (4.44e-1)" "unprognostic (6.15e-2)" "unprognostic (5.88e-2)" "unprognostic (6.30e-2)" "unprognostic (2.13e-1)" "unprognostic (3.42e-2)" "unprognostic (5.28e-3)" "unprognostic (5.16e-2)" "unprognostic (2.05e-2)" "unprognostic (2.37e-1)" "unprognostic (3.63e-2)" "unprognostic (4.63e-2)" "unprognostic (1.08e-1)" "unprognostic (5.86e-2)" "unprognostic (1.13e-1)" "unprognostic (3.95e-2)" "unprognostic (2.78e-2)" "unprognostic (1.48e-1)" "unprognostic (4.75e-2)" "unprognostic (1.00e-1)" "potential prognostic unfavorable (4.27e-4)" "unprognostic (1.63e-1)" "unprognostic (2.98e-1)" "unprognostic (2.54e-1)" "unprognostic (1.44e-2)" "unprognostic (1.23e-1)" "unprognostic (9.13e-2)" "unprognostic (1.63e-1)" "unprognostic (7.87e-2)" IYD "C6orf71, DEHAL1, dJ422F24.1" ENSG00000009765 "Iodotyrosine deiodinase" Q6PHW0 6 150368892-150405969 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" Oxidoreductase "Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "thyroid gland: 442.1" "Cell type enhanced" "Detected in some" "Colonocytes: 26.1;Enteric transient amplifying cells: 12.8;Enterocytes: 102.1;Foveolar cells: 14.0;Gastric progenitor cells: 24.4;Goblet cells: 33.1;Hepatocytes: 35.7;Paneth cells: 19.3;Proximal tubule cells: 99.3" "Group enriched" "Detected in some" 6 "lower rhombic lip: 6.7;thalamic excitatory: 1.7" "Cancer enriched" "Detected in many" 17 "Thyroid Carcinoma (TCGA): 163.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.0" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in some" "colorectal cancer: 2.8;Gastric cancer: 2.2" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells, Thyroid gland - Thyroid glandular cells" "Group enriched" "Detected in some" 13 "hippocampal formation: 7.4;thalamus: 2.4" "Low region specificity" "Detected in all" HPA059627 Enhanced Supported "Plasma membrane" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 33: Thyroid gland - Tissue development" "Cluster 48: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 1: Enterocytes - Absorption and Digestion" 1 "Plasma membrane" "HPA059627: " "unprognostic (3.11e-2)" "unprognostic (1.34e-1)" "unprognostic (9.88e-2)" "unprognostic (1.73e-1)" "unprognostic (1.14e-1)" "potential prognostic favorable (9.84e-6)" "unprognostic (2.10e-2)" "potential prognostic favorable (3.74e-4)" "unprognostic (1.04e-3)" "unprognostic (1.12e-1)" "unprognostic (2.22e-1)" "unprognostic (1.15e-1)" "unprognostic (1.23e-1)" "unprognostic (1.83e-2)" "unprognostic (3.79e-2)" "unprognostic (3.67e-2)" "unprognostic (2.23e-2)" IZUMO1 "IZUMO, MGC34799, OBF" ENSG00000182264 "Izumo sperm-egg fusion 1" Q8IYV9 19 48740852-48746909 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Fertilization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "testis: 17.5" "Group enriched" "Detected in some" 6 "Early spermatids: 188.4;Late primary spermatocytes: 70.1;Late spermatids: 146.5" "Cell type enhanced" "Detected in some" "upper rhombic lip: 2.8" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 1.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Vascular endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA038104 Enhanced NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 35: Non-specific - DNA binding" "Cluster 13: Non-specific - Mixed function" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 2 "HPA038104: " IZUMO1R "Folbp3, FOLR4, JUNO" ENSG00000183560 "IZUMO1 receptor, JUNO" A6ND01 11 94304580-94308146 "Predicted intracellular proteins, Transporters" Fertilization Receptor "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 32 "Oocytes: 4.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "basal ganglia: 1.0" NA NA "Cluster 51: Myeloma - Immunoglobulins" "Cluster 41: Oocytes - Oogenesis" IZUMO2 "C19orf41, MGC33947, SCRL" ENSG00000161652 "IZUMO family member 2" Q6UXV1 19 50152548-50163281 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 416 "testis: 54.6" "Group enriched" "Detected in some" 68 "Early spermatids: 853.5;Late primary spermatocytes: 358.2;Late spermatids: 416.8" "Cell type enhanced" "Detected in some" "mammillary body: 2.7" "Cancer enhanced" "Detected in single" "Rectum Adenocarcinoma (TCGA): 1.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA042143 Uncertain Approved "Acrosome,Mid piece" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 51: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" Acrosome "Mid piece" "HPA042143: " "unprognostic (5.89e-3)" "unprognostic (6.48e-3)" "unprognostic (4.76e-2)" IZUMO3 "bA20A20.1, C9orf134" ENSG00000205442 "IZUMO family member 3" Q5VZ72 9 24542952-24545946 "Predicted membrane proteins, Transporters" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 130 "testis: 12.9" "Group enriched" "Detected in some" 69 "Early spermatids: 211.8;Late primary spermatocytes: 189.0;Late spermatids: 142.5" "Cell type enriched" "Detected in some" 5 "lower rhombic lip: 8.5" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 17 "Sarcoma: 5.6" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA045722 Approved "Acrosome,Equatorial segment" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 24: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" "Acrosome, Equatorial segment" "HPA045722: " IZUMO4 C19orf36 ENSG00000099840 "IZUMO family member 4" Q1ZYL8 19 2096429-2099593 "Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 23 "testis: 430.4" "Group enriched" "Detected in many" 21 "Early spermatids: 1650.2;Late primary spermatocytes: 2332.3;Late spermatids: 4016.7" "Cell type enhanced" "Detected in all" "astrocyte: 34.8;Bergmann glia: 55.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 5 "lymphoma: 10.8;Myeloma: 6.9;Rhabdoid: 2.9" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048496 Enhanced Approved "Equatorial segment,Calyx,Connecting piece" "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 23: Testis - Spermatogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" "Equatorial segment, Calyx, Connecting piece" "HPA048496: " "unprognostic (9.63e-2)" "unprognostic (8.09e-3)" "unprognostic (1.65e-2)" "unprognostic (2.38e-2)" "unprognostic (3.16e-1)" "unprognostic (7.12e-3)" "unprognostic (3.09e-1)" "unprognostic (1.23e-2)" "unprognostic (3.72e-1)" "unprognostic (3.31e-2)" "unprognostic (2.26e-2)" "unprognostic (3.40e-2)" "unprognostic (3.94e-3)" "unprognostic (7.00e-2)" "unprognostic (9.10e-2)" "unprognostic (1.04e-1)" "unprognostic (1.77e-2)" "unprognostic (1.47e-2)" "unprognostic (3.78e-3)" "unprognostic (1.78e-1)" "unprognostic (1.74e-1)" "unprognostic (7.42e-2)" "unprognostic (1.46e-1)" "unprognostic (6.69e-2)" JADE1 "JADE-1, PHF17" ENSG00000077684 "Jade family PHD finger 1" Q6IE81 4 128809700-128875224 "Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pituicytes/FSCs: 247.7;Renal collecting duct intercalated cells: 426.4;Salivary ionocytes: 241.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Macrophages, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020016, HPA072897" Approved Supported Nucleoplasm,Centrosome NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 8: Pancreas - Proteolysis" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 19 Nucleoplasm Centrosome "HPA020016: , HPA072897: " "unprognostic (1.60e-1)" "unprognostic (3.28e-2)" "unprognostic (1.36e-1)" "unprognostic (1.84e-1)" "unprognostic (1.52e-3)" "unprognostic (2.05e-1)" "unprognostic (2.18e-1)" "unprognostic (2.75e-2)" "unprognostic (1.55e-1)" "potential prognostic favorable (1.28e-4)" "unprognostic (3.10e-3)" "unprognostic (4.66e-2)" "unprognostic (4.85e-2)" "unprognostic (7.89e-3)" "unprognostic (3.30e-1)" "unprognostic (1.15e-1)" "unprognostic (2.16e-1)" "unprognostic (2.44e-2)" "unprognostic (7.07e-3)" "unprognostic (7.08e-2)" "unprognostic (1.78e-1)" "unprognostic (9.80e-2)" "unprognostic (9.07e-2)" "unprognostic (9.41e-2)" "unprognostic (1.57e-1)" "unprognostic (2.20e-3)" "unprognostic (1.14e-1)" "unprognostic (9.90e-2)" "unprognostic (1.98e-2)" JADE2 "JADE-2, KIAA0239, PHF15" ENSG00000043143 "Jade family PHD finger 2" Q9NQC1 5 134524312-134583230 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025959, HPA055789" Uncertain Enhanced Nucleoplasm NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 11 Nucleoplasm "HPA025959: , HPA055789: " "unprognostic (3.47e-2)" "unprognostic (2.10e-1)" "unprognostic (4.03e-1)" "unprognostic (3.25e-1)" "unprognostic (1.17e-1)" "unprognostic (1.16e-1)" "unprognostic (5.76e-2)" "unprognostic (1.17e-1)" "unprognostic (5.17e-2)" "validated prognostic favorable (3.44e-7)" "validated prognostic favorable (7.14e-4)" "unprognostic (6.15e-2)" "unprognostic (3.22e-2)" "unprognostic (2.34e-1)" "unprognostic (2.53e-1)" "unprognostic (5.36e-2)" "unprognostic (1.87e-1)" "potential prognostic unfavorable (5.61e-4)" "unprognostic (1.43e-1)" "unprognostic (1.49e-1)" "unprognostic (1.47e-2)" "unprognostic (1.10e-1)" "unprognostic (7.14e-3)" "unprognostic (6.87e-2)" "unprognostic (3.33e-1)" "unprognostic (3.65e-1)" "unprognostic (3.25e-2)" "unprognostic (1.47e-2)" "unprognostic (2.23e-1)" JADE3 "JADE-3, KIAA0215, PHF16" ENSG00000102221 "Jade family PHD finger 3" Q92613 X 46912276-47061242 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 200.2;B-cells: 146.0;Early primary spermatocytes: 151.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.8;naive B-cell: 1.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Spleen - B-cells (Spleen), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA006007, HPA064697" Uncertain Approved Nucleoplasm,Nucleoli NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 22: Epididymis - Mixed function" "Cluster 30: White matter - Myelination" "Cluster 36: Non-specific - mRNA processing" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 16 "Nucleoplasm, Nucleoli" "HPA006007: , HPA064697: " "unprognostic (1.46e-1)" "unprognostic (9.68e-2)" "unprognostic (1.88e-1)" "unprognostic (3.72e-2)" "unprognostic (3.22e-1)" "unprognostic (9.93e-3)" "potential prognostic favorable (2.00e-4)" "unprognostic (1.22e-1)" "unprognostic (1.11e-1)" "validated prognostic favorable (2.99e-5)" "validated prognostic favorable (7.58e-4)" "potential prognostic unfavorable (1.21e-4)" "unprognostic (9.44e-3)" "unprognostic (3.23e-1)" "unprognostic (1.35e-1)" "unprognostic (1.42e-1)" "unprognostic (3.02e-1)" "unprognostic (9.06e-2)" "unprognostic (1.07e-1)" "unprognostic (6.34e-3)" "unprognostic (1.38e-1)" "unprognostic (1.50e-1)" "unprognostic (2.44e-2)" "unprognostic (9.11e-2)" "unprognostic (1.42e-1)" "unprognostic (1.79e-2)" "unprognostic (1.62e-1)" "unprognostic (6.26e-2)" "unprognostic (1.23e-1)" JAG1 "AGS, AHD, AWS, CD339, HJ1, JAGL1" ENSG00000101384 "Jagged canonical Notch ligand 1" P78504 20 10637684-10673999 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Notch signaling pathway" "Developmental protein" "Charcot-Marie-Tooth disease, Deafness, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 300.0;Ocular epithelial cells: 180.3;Pericytes: 221.4;Vascular smooth muscle cells: 380.0" "Cell type enhanced" "Detected in many" "pericyte: 204.2;vascular associated smooth muscle cell: 624.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Kidney - Fibroblasts, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010343, HPA021555" Supported Approved "Golgi apparatus,Plasma membrane" NA NA 3400000 "Cluster 29: Non-specific - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 9 "Golgi apparatus, Plasma membrane" "CAB010343: , HPA021555: " "unprognostic (1.69e-2)" "unprognostic (1.33e-1)" "unprognostic (4.28e-3)" "unprognostic (2.45e-2)" "unprognostic (2.66e-1)" "unprognostic (4.74e-1)" "unprognostic (1.65e-1)" "unprognostic (8.26e-2)" "unprognostic (1.79e-1)" "unprognostic (1.00e-1)" "validated prognostic favorable (1.07e-6)" "validated prognostic favorable (6.60e-4)" "unprognostic (6.19e-2)" "unprognostic (4.18e-2)" "unprognostic (2.44e-1)" "unprognostic (1.12e-3)" "unprognostic (1.02e-2)" "unprognostic (1.48e-2)" "unprognostic (1.22e-1)" "unprognostic (2.18e-1)" "unprognostic (2.46e-1)" "potential prognostic unfavorable (2.92e-5)" "unprognostic (2.33e-1)" "unprognostic (5.25e-2)" "unprognostic (7.50e-2)" "potential prognostic favorable (2.39e-4)" "unprognostic (2.13e-1)" "unprognostic (2.06e-1)" "unprognostic (1.42e-1)" "unprognostic (3.01e-1)" "unprognostic (2.29e-1)" JAG2 ENSG00000184916 "Jagged canonical Notch ligand 2" Q9Y219 14 105140982-105168824 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Notch signaling pathway" "Developmental protein" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 31.0;Basal prostatic cells: 38.8;Breast myoepithelial cells: 73.2;Corticotrophs: 67.5;Epididymal basal cells: 34.7;Medullary thymic epithelial cells: 26.4;Respiratory basal cells: 30.6;Salivary basal cells: 37.9;Salivary myoepithelial cells: 26.2;Vascular endothelial cells: 42.8" "Cell type enhanced" "Detected in many" "endothelial cell: 75.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Colon - Endothelial cells, Minor Salivary Gland - Endothelial cells, Pituitary gland - Corticotropes, Prostate - Prostate basal glandular cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025481, HPA030636, HPA050567" Approved Approved Vesicles NA NA 240000 "Cluster 2: Non-specific - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 6 Vesicles "CAB025481: , HPA030636: , HPA050567: " "unprognostic (3.57e-1)" "unprognostic (4.44e-2)" "unprognostic (3.36e-1)" "unprognostic (7.54e-2)" "unprognostic (8.45e-3)" "unprognostic (2.31e-1)" "unprognostic (1.87e-1)" "unprognostic (6.76e-2)" "unprognostic (5.45e-2)" "unprognostic (6.42e-2)" "validated prognostic favorable (6.73e-7)" "validated prognostic favorable (5.37e-4)" "unprognostic (1.06e-2)" "unprognostic (7.08e-2)" "unprognostic (5.80e-2)" "unprognostic (2.90e-2)" "unprognostic (1.85e-1)" "unprognostic (1.14e-1)" "unprognostic (1.05e-1)" "unprognostic (1.79e-1)" "unprognostic (1.32e-1)" "unprognostic (1.70e-2)" "unprognostic (3.36e-3)" "unprognostic (3.08e-1)" "unprognostic (3.11e-1)" "unprognostic (5.93e-2)" "unprognostic (5.49e-2)" "unprognostic (1.37e-1)" "unprognostic (1.52e-1)" "unprognostic (1.73e-1)" "unprognostic (5.59e-3)" JAGN1 "FLJ14602, GL009" ENSG00000171135 "Jagunal homolog 1" Q8N5M9 3 9890574-9894349 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Adrenal cortex cells, Heart muscle - Macrophages, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" HPA067610 Approved Vesicles NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 70: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 97: Non-specific - Cellular respiration" 110 Vesicles "HPA067610: " "unprognostic (1.95e-2)" "unprognostic (2.53e-2)" "unprognostic (3.09e-1)" "unprognostic (8.50e-2)" "unprognostic (8.99e-2)" "unprognostic (1.40e-1)" "unprognostic (3.32e-2)" "unprognostic (4.67e-2)" "unprognostic (9.01e-2)" "unprognostic (5.82e-2)" "unprognostic (1.12e-3)" "unprognostic (1.24e-1)" "unprognostic (3.30e-2)" "validated prognostic unfavorable (1.33e-4)" "validated prognostic unfavorable (1.39e-9)" "unprognostic (6.34e-3)" "unprognostic (2.96e-1)" "unprognostic (1.80e-1)" "unprognostic (1.51e-1)" "unprognostic (4.56e-3)" "unprognostic (1.54e-1)" "unprognostic (5.93e-2)" "unprognostic (2.83e-1)" "unprognostic (2.00e-1)" "unprognostic (1.99e-1)" "unprognostic (3.34e-1)" "unprognostic (1.68e-2)" "unprognostic (9.38e-2)" "unprognostic (3.14e-1)" "unprognostic (2.03e-1)" "unprognostic (3.93e-1)" JAK1 "JAK1A, JAK1B, JTK3" ENSG00000162434 "Janus kinase 1" P23458 1 64833223-65067754 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 1354.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB013088 Approved NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 15: Kidney cancer - Membrane components" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 66 "CAB013088: " "unprognostic (1.02e-2)" "unprognostic (4.40e-3)" "unprognostic (5.56e-3)" "unprognostic (3.28e-1)" "unprognostic (4.31e-2)" "unprognostic (2.40e-1)" "unprognostic (4.17e-2)" "unprognostic (2.12e-2)" "unprognostic (1.39e-1)" "unprognostic (2.41e-3)" "validated prognostic favorable (9.34e-9)" "validated prognostic favorable (2.87e-4)" "unprognostic (2.85e-1)" "unprognostic (6.04e-2)" "unprognostic (2.27e-1)" "unprognostic (2.12e-2)" "unprognostic (6.32e-2)" "unprognostic (3.42e-2)" "unprognostic (8.80e-2)" "unprognostic (3.69e-2)" "unprognostic (1.72e-2)" "unprognostic (4.78e-2)" "unprognostic (2.50e-2)" "unprognostic (6.79e-2)" "unprognostic (6.49e-2)" "unprognostic (2.85e-2)" "unprognostic (1.21e-1)" "unprognostic (1.49e-1)" "unprognostic (9.94e-2)" "unprognostic (2.06e-1)" "unprognostic (4.17e-3)" JAK2 JTK10 ENSG00000096968 "Janus kinase 2" O60674 9 4984390-5129948 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity" "Chromatin regulator, Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglia: 371.0;Myonuclei: 421.3;Neutrophil progenitors: 438.8;Neutrophils: 666.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 133.0" "Lineage enriched" "Detected in all" 5 "granulocytes: 133.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013089, HPA040820, HPA043870" Approved Supported "Nucleoplasm,Plasma membrane,Focal adhesion sites" No No "Cluster 46: Basophils - Proteolysis" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 53: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 44 Nucleoplasm "Plasma membrane, Focal adhesion sites" "CAB013089: , HPA040820: , HPA043870: " "unprognostic (2.70e-2)" "unprognostic (5.40e-3)" "unprognostic (1.83e-1)" "unprognostic (2.05e-1)" "unprognostic (3.78e-2)" "unprognostic (2.35e-1)" "unprognostic (1.42e-1)" "unprognostic (1.00e-1)" "unprognostic (6.81e-3)" "unprognostic (2.82e-2)" "potential prognostic favorable (1.07e-4)" "unprognostic (1.09e-1)" "unprognostic (2.43e-3)" "unprognostic (2.89e-1)" "unprognostic (3.10e-2)" "unprognostic (1.21e-2)" "unprognostic (9.70e-2)" "unprognostic (9.49e-2)" "unprognostic (2.15e-1)" "unprognostic (6.38e-3)" "unprognostic (7.43e-2)" "unprognostic (1.49e-1)" "unprognostic (5.42e-2)" "unprognostic (3.80e-2)" "unprognostic (8.10e-3)" "unprognostic (4.82e-2)" "unprognostic (5.27e-2)" "unprognostic (2.30e-2)" "unprognostic (1.77e-1)" "unprognostic (5.43e-2)" "unprognostic (9.78e-3)" JAK3 "JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK" ENSG00000105639 "Janus kinase 3" P52333 19 17824780-17848071 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 53.3" "Cell type enhanced" "Detected in many" "B-cells: 53.0;Hematopoietic stem cells: 76.2;Megakaryocytes: 105.1;Neutrophil progenitors: 223.2;Neutrophils: 437.0;NK-cells: 58.3;Platelets: 70.3;T-cells: 67.6;Thymocytes: 52.5" "Group enriched" "Detected in many" 4 "central nervous system macrophage: 20.5;leukocyte: 70.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 10 "Leukemia: 6.1;lymphoma: 11.9;Myeloma: 9.4" "Prostate - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA070314 Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 5: Spleen - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 24: Neutrophils - Innate immunity signal integration" 25 "Plasma membrane, Cytosol" "HPA070314: " "unprognostic (2.33e-1)" "unprognostic (2.97e-2)" "unprognostic (3.54e-2)" "unprognostic (1.20e-2)" "unprognostic (1.29e-1)" "unprognostic (1.59e-1)" "unprognostic (6.24e-3)" "unprognostic (1.86e-1)" "potential prognostic favorable (1.89e-4)" "unprognostic (6.31e-2)" "potential prognostic unfavorable (1.36e-8)" "unprognostic (3.30e-2)" "unprognostic (1.58e-1)" "unprognostic (2.37e-1)" "unprognostic (1.85e-2)" "unprognostic (9.87e-2)" "unprognostic (6.26e-2)" "unprognostic (6.45e-2)" "unprognostic (7.92e-2)" "unprognostic (1.63e-1)" "unprognostic (1.45e-1)" "unprognostic (2.49e-2)" "potential prognostic unfavorable (2.50e-4)" "unprognostic (2.48e-1)" "unprognostic (1.54e-1)" "unprognostic (3.70e-2)" "unprognostic (6.28e-3)" "unprognostic (1.27e-1)" "unprognostic (1.28e-2)" "unprognostic (3.91e-2)" "unprognostic (1.31e-1)" JAKMIP1 "FLJ31564, Gababrbp, JAMIP1, MARLIN1" ENSG00000152969 "Janus kinase and microtubule interacting protein 1" Q96N16 4 6026199-6200591 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 70.0" "Group enriched" "Detected in some" 8 "Astrocytes: 57.5;Brain excitatory neurons: 102.6;Brain inhibitory neurons: 168.5;Other brain neurons: 98.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 18 "gdT-cell: 25.1;MAIT T-cell: 11.0;memory CD4 T-cell: 10.9;memory CD8 T-cell: 22.3;naive CD8 T-cell: 9.9;T-reg: 36.5" "Lineage enriched" "Detected in many" 35 "T-cells: 36.5" "Group enriched" "Detected in some" 4 "Leukemia: 4.9;lung cancer: 3.0;lymphoma: 10.0;Myeloma: 9.4;Neuroblastoma: 8.0" "Adrenal gland - Adrenal medulla cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044570 Uncertain NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 35: Neurons - Synaptic function & neurogenesis" 15 "HPA044570: " "unprognostic (2.25e-1)" "unprognostic (7.59e-2)" "unprognostic (4.45e-3)" "unprognostic (3.60e-2)" "unprognostic (2.51e-1)" "unprognostic (3.12e-2)" "unprognostic (7.52e-2)" "unprognostic (1.48e-2)" "unprognostic (1.82e-1)" "unprognostic (4.85e-3)" "unprognostic (9.55e-2)" "unprognostic (1.01e-1)" "unprognostic (3.78e-2)" JAKMIP2 "JAMIP2, KIAA0555" ENSG00000176049 "Janus kinase and microtubule interacting protein 2" Q96AA8 5 147585438-147782775 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.2;pituitary gland: 7.8" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 276.6;Astrocytes: 250.4;Bergmann glia: 199.8;Brain excitatory neurons: 350.7;Brain inhibitory neurons: 248.1;Corticotrophs: 281.0;Ependymal cells: 328.7;Gonadotrophs: 458.3;Lactotrophs: 218.6;Oligodendrocyte progenitor cells: 195.6;Oligodendrocytes: 250.7;Other brain neurons: 235.6;Retinal amacrine cells: 195.7;Retinal ganglion cells: 367.0;Retinal horizontal cells: 394.7;Somatotrophs: 239.7;Thyrotrophs: 399.1" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Glioblastoma Multiforme (TCGA): 17.7;Lung Squamous Cell Carcinoma (TCGA): 4.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 7.3;MAIT T-cell: 5.3;memory CD4 T-cell: 2.8;memory CD8 T-cell: 5.5;naive CD8 T-cell: 4.6;NK-cell: 7.0" "Group enriched" "Detected in many" 6 "NK-cells: 7.0;T-cells: 7.3" "Cancer enhanced" "Detected in many" "Bone cancer: 24.7" "Kidney - Podocytes, Liver - Hepatocytes, Prostate - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046929, HPA065023" Approved Supported "Golgi apparatus" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 27: Cerebellum - Synaptic function" "Cluster 16: Non-specific - Transcription" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 13 "Golgi apparatus" "HPA046929: , HPA065023: " "unprognostic (3.50e-2)" "unprognostic (3.57e-1)" "unprognostic (1.44e-1)" "unprognostic (8.62e-2)" "potential prognostic favorable (1.36e-5)" "unprognostic (1.58e-1)" "unprognostic (4.82e-2)" "unprognostic (5.35e-2)" "unprognostic (2.65e-3)" "potential prognostic favorable (6.67e-4)" "unprognostic (2.62e-1)" "unprognostic (1.02e-1)" JAKMIP3 "bA140A10.5, C10orf14, C10orf39, FLJ37857, KIAA4091, NECC2" ENSG00000188385 "Janus kinase and microtubule interacting protein 3" Q5VZ66 10 132036336-132184858 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.2;pituitary gland: 3.7" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 42.5;Brain excitatory neurons: 46.4;Brain inhibitory neurons: 44.6;Choroid plexus epithelial cells: 27.1;Gonadotrophs: 50.3;Lactotrophs: 67.3;Oligodendrocyte progenitor cells: 48.6;Oligodendrocytes: 93.7;Other brain neurons: 49.2;Retinal amacrine cells: 32.9;Retinal ganglion cells: 30.9;Somatotrophs: 48.6;Thyrotrophs: 55.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in single" "Lung Squamous Cell Carcinoma (TCGA): 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022872 Uncertain NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 109: Neurons - Neuronal signaling" "HPA022872: " "unprognostic (2.39e-1)" "unprognostic (1.41e-2)" "unprognostic (1.31e-1)" "unprognostic (8.94e-3)" JAM2 "C21orf43, CD322, JAM-2, JAM-B, JAMB, VE-JAM" ENSG00000154721 "Junctional adhesion molecule 2" P57087 21 25639258-25717562 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 59.6" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 76.3;Astrocytes: 114.8;Bergmann glia: 150.5;Cardiomyocytes: 93.0;Cone photoreceptor cells: 64.2;Microglia: 101.3;Oligodendrocyte progenitor cells: 75.6;Pituicytes/FSCs: 107.5;Sertoli cells: 322.1;Vascular endothelial cells: 268.7" "Cell type enhanced" "Detected in all" "endothelial cell: 440.2" "Cancer enriched" "Detected in all" 8 "Glioblastoma Multiforme (TCGA): 54.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 9.7;Rhabdoid: 8.5" "Adipose subcutaneous - Endothelial cells, Adrenal gland - Adrenal cortex cells, Colon - Enteric glia cells, Liver - Vascular endothelial cells, Skeletal muscle - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028789, HPA077346" Supported "Nucleoplasm,Plasma membrane" NA NA 32000 "Cluster 24: Non-specific - Transcription" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 2 "Plasma membrane" Nucleoplasm "HPA028789: , HPA077346: " "unprognostic (1.17e-2)" "unprognostic (2.08e-1)" "unprognostic (2.05e-1)" "unprognostic (1.59e-1)" "unprognostic (5.18e-2)" "unprognostic (1.88e-1)" "unprognostic (1.16e-1)" "unprognostic (4.36e-1)" "unprognostic (2.46e-2)" "unprognostic (5.39e-2)" "potential prognostic favorable (3.68e-6)" "unprognostic (1.41e-3)" "unprognostic (2.49e-3)" "potential prognostic favorable (5.83e-4)" "unprognostic (2.26e-3)" "unprognostic (1.71e-2)" "unprognostic (2.46e-3)" "unprognostic (1.12e-2)" "unprognostic (2.88e-1)" "unprognostic (1.72e-2)" "unprognostic (1.47e-1)" "unprognostic (4.92e-2)" "unprognostic (4.39e-1)" "unprognostic (1.38e-1)" "unprognostic (5.08e-2)" "unprognostic (4.91e-2)" "unprognostic (8.14e-2)" "unprognostic (3.26e-3)" "unprognostic (2.23e-1)" "unprognostic (1.34e-1)" "unprognostic (1.53e-2)" JAM3 "JAM-3, JAM-C, JAMC" ENSG00000166086 "Junctional adhesion molecule 3" Q9BX67 11 134069071-134152001 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion, Differentiation, Spermatogenesis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 255.8;Oligodendrocytes: 383.7;Platelets: 216.5;Respiratory ionocytes: 188.0;Rod photoreceptor cells: 321.3;Sertoli cells: 203.9;Thymic myoid cells: 168.6" "Cell type enhanced" "Detected in all" "oligodendrocyte: 490.3" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 52.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 5.3" "Group enriched" "Detected in many" 7 "B-cells: 5.3;T-cells: 2.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003417, HPA050434" Approved Uncertain "Golgi apparatus" "Secreted to blood" "Cell adhesion" NA NA 33000 "Cluster 24: Non-specific - Transcription" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 79: Photoreceptor cells - Phototransduction" 6 "Golgi apparatus" "HPA003417: , HPA050434: " "unprognostic (1.72e-1)" "unprognostic (2.06e-1)" "unprognostic (1.54e-1)" "unprognostic (1.84e-2)" "unprognostic (2.37e-2)" "unprognostic (1.57e-1)" "unprognostic (2.69e-1)" "unprognostic (2.78e-1)" "unprognostic (1.79e-1)" "unprognostic (4.21e-2)" "potential prognostic favorable (5.90e-6)" "unprognostic (3.16e-3)" "unprognostic (1.39e-2)" "unprognostic (3.95e-2)" "unprognostic (4.41e-2)" "unprognostic (6.23e-3)" "unprognostic (1.02e-1)" "unprognostic (6.99e-3)" "unprognostic (6.89e-2)" "unprognostic (1.43e-2)" "potential prognostic unfavorable (6.95e-4)" "unprognostic (4.30e-2)" "unprognostic (2.83e-2)" "unprognostic (3.82e-2)" "unprognostic (9.86e-2)" "unprognostic (2.83e-2)" "unprognostic (2.37e-1)" "unprognostic (5.13e-3)" "unprognostic (1.96e-1)" "unprognostic (1.00e-3)" "unprognostic (9.22e-2)" JAML "AMICA, AMICA1, Gm638" ENSG00000160593 "Junction adhesion molecule like" Q86YT9 11 118193725-118225094 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 40.7;lymphoid tissue: 64.8" "Cell type enhanced" "Detected in many" "cDC: 419.8;Hematopoietic stem cells: 70.4;Innate lymphoid cells: 120.2;Macrophages: 136.8;monocytes: 203.1;Neutrophils: 649.0;pDCs: 284.8;T-cells: 160.5" "Cell type enriched" "Detected in some" 7 "leukocyte: 106.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in all" "eosinophil: 3539.1" "Group enriched" "Detected in all" 5 "dendritic cells: 1018.9;granulocytes: 3539.1;monocytes: 1025.5" "Group enriched" "Detected in some" 11 "Leukemia: 7.5;lymphoma: 18.0" "Adipose subcutaneous - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Prostate - T-cells, Skin - T-cells, Spleen - Neutrophils_2, Stomach - T-cells, Thyroid gland - T-cells" "Region enriched" "Detected in many" 11 "cerebellum: 63.6" "HPA005854, HPA047919" Approved Supported "Nucleoplasm,Plasma membrane" NA NA 1000000 "Cluster 7: Non-specific - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 25: Non-specific - Transcription" "Cluster 59: Leukemia - T-cell receptor" "Cluster 24: Neutrophils - Innate immunity signal integration" "Plasma membrane" Nucleoplasm "HPA005854: , HPA047919: " "unprognostic (7.91e-3)" "unprognostic (2.20e-2)" "unprognostic (2.63e-3)" "unprognostic (8.83e-2)" "unprognostic (1.54e-1)" "potential prognostic unfavorable (3.75e-5)" "unprognostic (2.31e-1)" "potential prognostic favorable (6.22e-4)" "unprognostic (4.34e-2)" "unprognostic (1.46e-2)" "unprognostic (1.05e-1)" "unprognostic (3.54e-2)" "unprognostic (1.14e-1)" "potential prognostic favorable (6.64e-4)" "unprognostic (8.17e-2)" "unprognostic (1.02e-1)" "unprognostic (2.19e-1)" "unprognostic (3.94e-1)" "unprognostic (6.06e-2)" "unprognostic (8.68e-2)" "unprognostic (3.52e-2)" "unprognostic (4.46e-1)" "unprognostic (9.35e-2)" "unprognostic (1.22e-2)" "unprognostic (6.91e-2)" "unprognostic (4.65e-2)" "unprognostic (4.25e-2)" "unprognostic (1.49e-2)" "unprognostic (1.93e-1)" JARID2 JMJ ENSG00000008083 "Jumonji and AT-rich interaction domain containing 2" Q92833 6 15246069-15522042 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Chromatin regulator, Developmental protein, Repressor" "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 54.5" "Cell type enhanced" "Detected in all" "cDC: 977.3;Endometrial luminal cells: 1052.2;monocytes: 2368.8;Neutrophils: 1191.5" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 58.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "testis cancer: 71.9" "Stomach - Gastric mucous cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063889, CAB069890" Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 15: Non-specific - Transcription" "Cluster 34: Testis cancer - Unknown function" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 14 "Nucleoplasm, Mitochondria" "CAB069890: , HPA063889: " "unprognostic (8.88e-2)" "unprognostic (2.95e-2)" "unprognostic (4.88e-3)" "unprognostic (1.16e-1)" "unprognostic (6.51e-2)" "unprognostic (1.66e-1)" "unprognostic (4.85e-2)" "unprognostic (4.19e-3)" "unprognostic (1.36e-1)" "unprognostic (6.78e-3)" "unprognostic (2.15e-2)" "unprognostic (2.67e-3)" "unprognostic (2.63e-1)" "potential prognostic unfavorable (7.84e-4)" "unprognostic (2.27e-1)" "unprognostic (8.66e-2)" "unprognostic (2.93e-1)" "unprognostic (1.96e-1)" "unprognostic (1.32e-3)" "unprognostic (5.01e-2)" "unprognostic (1.03e-1)" "unprognostic (9.30e-2)" "potential prognostic unfavorable (5.89e-4)" "unprognostic (5.37e-2)" "unprognostic (1.31e-2)" "unprognostic (8.25e-2)" "unprognostic (1.61e-3)" "unprognostic (2.25e-2)" "unprognostic (5.51e-2)" "unprognostic (1.36e-3)" "unprognostic (5.01e-2)" JAZF1 "DKFZp761K2222, TIP27, ZNF802" ENSG00000153814 "JAZF zinc finger 1" Q86VZ6 7 27830573-28180795 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Lipid metabolism, Transcription, Transcription regulation" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 79.2" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 1267.1;Microglia: 758.5;Pituitary stem cells: 742.9;Sertoli cells: 962.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 25.8" "Group enriched" "Detected in all" 4 "dendritic cells: 14.2;granulocytes: 25.8" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019271, HPA066967" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Primary cilium tip,Cytosol" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 16 "Nucleoplasm, Nucleoli fibrillar center" "Primary cilium tip, Cytosol" "CAB019271: , HPA066967: " "unprognostic (3.81e-2)" "unprognostic (2.66e-1)" "unprognostic (1.25e-1)" "unprognostic (4.81e-2)" "unprognostic (3.29e-2)" "unprognostic (4.70e-2)" "unprognostic (9.77e-2)" "unprognostic (1.38e-1)" "unprognostic (5.25e-2)" "unprognostic (2.43e-1)" "unprognostic (2.50e-3)" "unprognostic (1.45e-2)" "unprognostic (3.99e-2)" "unprognostic (7.88e-2)" "unprognostic (3.07e-2)" "unprognostic (3.99e-2)" "unprognostic (5.85e-2)" "unprognostic (1.19e-1)" "unprognostic (7.56e-2)" "unprognostic (9.76e-3)" "unprognostic (7.08e-3)" "unprognostic (7.05e-3)" "unprognostic (4.14e-2)" "unprognostic (1.33e-2)" "unprognostic (8.11e-3)" "unprognostic (8.25e-2)" "unprognostic (1.63e-1)" "unprognostic (1.73e-3)" "unprognostic (2.60e-1)" "unprognostic (1.39e-1)" "unprognostic (1.53e-1)" JCAD KIAA1462 ENSG00000165757 "Junctional cadherin 5 associated" Q9P266 10 30012803-30115494 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 69.5;Cone photoreceptor cells: 66.2;Granulosa cells: 65.7;Lymphatic endothelial cells: 56.6;Medullary thymic epithelial cells: 108.0;Pancreatic duct cells: 88.4;Retinal bipolar cells: 66.9;Retinal horizontal cells: 128.2;Retinal pigment epithelial cells: 55.4;Sertoli cells: 213.8;Smooth muscle cells: 50.2;Vascular endothelial cells: 128.3" "Cell type enhanced" "Detected in many" "endothelial cell: 444.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 23.0" "Adipose visceral - Endothelial cells, Adrenal gland - Fibroblasts, Breast - Endothelial cells, Heart muscle - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Skeletal muscle - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017956 Enhanced Approved "Vesicles,Cell Junctions" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 53: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 104: Brain endothelial cells - Blood brain barrier" 7 "Vesicles, Cell Junctions" "HPA017956: " "unprognostic (6.04e-2)" "unprognostic (3.89e-1)" "potential prognostic unfavorable (3.38e-5)" "unprognostic (1.32e-1)" "unprognostic (7.17e-2)" "unprognostic (1.62e-2)" "unprognostic (1.21e-1)" "unprognostic (5.89e-2)" "unprognostic (2.87e-1)" "validated prognostic favorable (1.56e-4)" "validated prognostic favorable (1.28e-4)" "unprognostic (1.75e-2)" "unprognostic (5.43e-2)" "unprognostic (8.32e-2)" "unprognostic (4.85e-2)" "unprognostic (1.27e-1)" "unprognostic (4.97e-1)" "unprognostic (1.30e-2)" "unprognostic (1.31e-2)" "unprognostic (3.31e-1)" "unprognostic (3.26e-1)" "unprognostic (1.08e-1)" "unprognostic (1.66e-1)" "unprognostic (2.46e-2)" "unprognostic (2.49e-2)" "potential prognostic unfavorable (4.14e-4)" "unprognostic (1.82e-1)" "unprognostic (7.47e-2)" "unprognostic (1.33e-1)" JCHAIN "IGCJ, IGJ, JCH" ENSG00000132465 "Joining chain of multimeric IgA and IgM" P01591 4 70655541-70681817 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 2822.4;intestine: 7466.4;stomach 1: 5567.4" "Cell type enriched" "Detected in some" 16 "Plasma cells: 61470.3" "Cell type enriched" "Detected in single" 25 "leukocyte: 17.5" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "spinal cord: 13.1" "Group enriched" "Detected in all" 122 "memory B-cell: 4194.2;naive B-cell: 2578.5;plasmacytoid DC: 3595.4" "Group enriched" "Detected in all" 137 "B-cells: 4194.2;dendritic cells: 3595.4" "Cancer enriched" "Detected in many" 10 "Myeloma: 12971.3" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB034436, HPA044132" Enhanced "Secreted to blood" "No annotated function" NA NA 2400000000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 77: Intestine - Digestion" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 67: Plasma cells - Plasma cell differentiation" 10 "CAB034436: , HPA044132: " "unprognostic (1.20e-2)" "potential prognostic favorable (1.61e-5)" "unprognostic (1.98e-2)" "unprognostic (3.81e-3)" "unprognostic (8.29e-2)" "unprognostic (1.36e-2)" "unprognostic (3.24e-1)" "potential prognostic favorable (1.40e-6)" "unprognostic (2.55e-1)" "unprognostic (9.76e-2)" "unprognostic (1.93e-1)" "unprognostic (3.05e-3)" "unprognostic (2.98e-2)" "unprognostic (1.84e-3)" "potential prognostic favorable (2.45e-4)" "unprognostic (1.22e-1)" "unprognostic (4.86e-2)" "unprognostic (7.84e-3)" "unprognostic (1.24e-1)" "unprognostic (2.48e-1)" "unprognostic (9.51e-2)" "unprognostic (2.14e-1)" "unprognostic (1.48e-2)" "unprognostic (3.80e-1)" "unprognostic (1.87e-1)" "unprognostic (1.62e-1)" "unprognostic (3.99e-2)" "unprognostic (2.19e-1)" "unprognostic (8.77e-2)" JDP2 JUNDM2 ENSG00000140044 "Jun dimerization protein 2" Q8WYK2 14 75427716-75474111 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 204.5;Kupffer cells: 282.9;Macrophages: 188.8;Monocyte progenitors: 241.2;monocytes: 321.4;Neutrophil progenitors: 315.1;Neutrophils: 272.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 11.9;granulocytes: 7.7;monocytes: 13.3" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Prostate - Fibroblasts, Skin - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059511 Supported Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 14 "Nucleoplasm, Nuclear speckles" "HPA059511: " "unprognostic (3.46e-3)" "unprognostic (7.32e-2)" "unprognostic (2.59e-2)" "unprognostic (1.17e-3)" "unprognostic (5.00e-2)" "unprognostic (1.49e-1)" "unprognostic (4.68e-2)" "unprognostic (2.03e-1)" "unprognostic (6.03e-2)" "unprognostic (1.49e-1)" "potential prognostic favorable (7.93e-6)" "unprognostic (1.07e-3)" "unprognostic (2.84e-1)" "unprognostic (2.12e-2)" "potential prognostic favorable (1.86e-4)" "unprognostic (3.65e-1)" "unprognostic (4.22e-2)" "unprognostic (1.52e-1)" "unprognostic (2.72e-2)" "unprognostic (3.11e-2)" "unprognostic (2.51e-2)" "unprognostic (4.47e-2)" "unprognostic (7.69e-2)" "unprognostic (1.09e-1)" "unprognostic (9.67e-2)" "unprognostic (1.09e-1)" "unprognostic (2.12e-2)" "unprognostic (2.53e-1)" "unprognostic (1.30e-1)" "unprognostic (1.63e-1)" "potential prognostic favorable (8.35e-4)" JHY "C11orf63, FLJ23554" ENSG00000109944 "Junctional cadherin complex regulator" Q6NUN7 11 122882683-122963862 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 16.1;testis: 33.4" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 215.1;Endometrial ciliated cells: 92.7;Ependymal cells: 163.7;Epididymal efferent duct ciliated cells: 86.9;Fallopian tube ciliated cells: 110.1;Late primary spermatocytes: 132.3;Late spermatids: 78.1;Podocytes: 76.9;Respiratory ciliated cells: 134.7" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 161.5;ependymal cell: 180.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Liver - Hepatic stellate cells, Testis - Early spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA039612, HPA040344, HPA077658, HPA077748" Enhanced Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 44: Non-specific - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 101: Choroid plexus epithelial cells - Ion transport" Nucleoplasm "Golgi apparatus" "HPA039612: , HPA040344: , HPA077658: , HPA077748: " "unprognostic (7.72e-2)" "unprognostic (3.70e-2)" "unprognostic (1.22e-1)" "unprognostic (2.74e-2)" "unprognostic (5.70e-2)" "validated prognostic unfavorable (4.88e-5)" "validated prognostic unfavorable (7.10e-5)" "unprognostic (7.85e-2)" "unprognostic (2.45e-3)" "potential prognostic favorable (7.46e-4)" "unprognostic (6.21e-3)" "unprognostic (1.16e-3)" "unprognostic (1.13e-1)" "unprognostic (8.35e-2)" "potential prognostic unfavorable (6.10e-5)" "unprognostic (8.96e-2)" "unprognostic (1.39e-1)" "unprognostic (2.86e-1)" "unprognostic (1.92e-2)" "unprognostic (1.72e-3)" "unprognostic (3.60e-1)" "unprognostic (3.21e-1)" "potential prognostic favorable (7.68e-5)" "unprognostic (6.21e-2)" "unprognostic (1.06e-2)" "unprognostic (1.22e-1)" "potential prognostic unfavorable (5.33e-4)" "unprognostic (6.70e-2)" JKAMP "C14orf100, CDA06, HSPC213, HSPC327, JAMP" ENSG00000050130 "JNK1/MAPK8 associated membrane protein" Q9P055 14 59484443-59505410 "Cancer-related genes, Predicted membrane proteins" "Unfolded protein response" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 169.7;Late primary spermatocytes: 206.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031172, HPA071650" Supported Approved Nucleoplasm,Vesicles NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 98: Neurons - Neurotransmission & signaling" 3 Vesicles Nucleoplasm "HPA031172: , HPA071650: " "unprognostic (1.47e-2)" "unprognostic (5.45e-2)" "unprognostic (2.30e-2)" "unprognostic (5.82e-1)" "unprognostic (2.67e-2)" "unprognostic (8.77e-3)" "unprognostic (2.40e-1)" "unprognostic (5.41e-2)" "unprognostic (5.16e-3)" "unprognostic (3.23e-1)" "potential prognostic favorable (6.71e-6)" "unprognostic (2.19e-2)" "unprognostic (1.02e-1)" "potential prognostic unfavorable (1.97e-5)" "unprognostic (9.40e-2)" "unprognostic (3.84e-2)" "unprognostic (1.14e-1)" "unprognostic (2.20e-2)" "potential prognostic unfavorable (6.32e-4)" "unprognostic (5.42e-2)" "potential prognostic unfavorable (5.28e-4)" "unprognostic (1.40e-1)" "unprognostic (3.43e-2)" "unprognostic (3.06e-1)" "unprognostic (2.54e-1)" "unprognostic (1.06e-1)" "unprognostic (6.13e-2)" "unprognostic (4.10e-2)" "unprognostic (1.88e-1)" "unprognostic (2.43e-1)" "unprognostic (2.18e-1)" JMJD1C "DKFZp761F0118, FLJ14374, KDM3C, KIAA1380, TRIP8" ENSG00000171988 "Jumonji domain containing 1C" Q15652 10 63167221-63521850 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 2309.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 14.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056175, HPA066195" Approved Supported Nucleoplasm,Cytosol No No "Cluster 20: Non-specific - DNA binding" "Cluster 61: Non-specific - Transcription" "Cluster 35: Non-specific - DNA binding" "Cluster 52: Non-specific - Mitochondria" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 11 Nucleoplasm Cytosol "HPA056175: , HPA066195: " "unprognostic (2.60e-1)" "unprognostic (3.41e-2)" "unprognostic (1.75e-1)" "unprognostic (1.09e-2)" "unprognostic (8.57e-2)" "unprognostic (7.35e-3)" "unprognostic (1.44e-2)" "potential prognostic favorable (1.09e-4)" "unprognostic (9.55e-2)" "unprognostic (8.06e-3)" "validated prognostic favorable (3.47e-6)" "validated prognostic favorable (2.66e-4)" "unprognostic (7.40e-2)" "unprognostic (1.06e-1)" "unprognostic (3.27e-3)" "unprognostic (1.81e-1)" "unprognostic (1.53e-1)" "unprognostic (4.86e-2)" "unprognostic (9.74e-2)" "unprognostic (3.60e-3)" "unprognostic (2.52e-2)" "unprognostic (2.73e-3)" "unprognostic (1.21e-2)" "unprognostic (1.91e-1)" "unprognostic (3.02e-2)" "unprognostic (4.96e-2)" "unprognostic (2.21e-1)" "unprognostic (2.83e-1)" "unprognostic (2.80e-1)" "unprognostic (5.72e-3)" "unprognostic (3.62e-1)" JMJD4 FLJ12517 ENSG00000081692 "Jumonji domain containing 4" Q9H9V9 1 227730425-227735411 "Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 53.3;Cardiomyocytes: 76.1;Early spermatids: 68.1;Epicardial cells: 84.1;Late primary spermatocytes: 91.0;Late spermatids: 331.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027260, HPA052861" Uncertain Uncertain "Vesicles,Plasma membrane" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 70: Non-specific - Protein processing" "Cluster 27: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 2 "Plasma membrane" Vesicles "HPA027260: , HPA052861: " "unprognostic (7.86e-2)" "unprognostic (1.27e-1)" "unprognostic (1.66e-2)" "unprognostic (1.20e-1)" "unprognostic (1.02e-1)" "unprognostic (5.23e-2)" "unprognostic (4.41e-3)" "potential prognostic favorable (3.12e-4)" "unprognostic (4.42e-1)" "unprognostic (1.19e-1)" "unprognostic (2.94e-1)" "potential prognostic unfavorable (2.81e-4)" "unprognostic (1.34e-2)" "unprognostic (6.33e-2)" "unprognostic (8.22e-2)" "unprognostic (1.73e-2)" "unprognostic (1.75e-3)" "unprognostic (1.12e-1)" "unprognostic (2.80e-1)" "unprognostic (1.54e-2)" "unprognostic (9.41e-2)" "unprognostic (2.70e-3)" "unprognostic (2.21e-1)" "unprognostic (1.05e-1)" "unprognostic (2.65e-1)" "unprognostic (8.06e-2)" "unprognostic (1.88e-1)" "unprognostic (7.50e-2)" "unprognostic (1.35e-1)" "unprognostic (7.48e-2)" "unprognostic (1.93e-2)" JMJD6 "KIAA0585, PTDSR, PTDSR1" ENSG00000070495 "Jumonji domain containing 6, arginine demethylase and lysine hydroxylase" Q6NYC1 17 76712832-76726799 "Essential proteins, Predicted intracellular proteins" "Differentiation, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Chromatin regulator, Developmental protein, Dioxygenase, Oxidoreductase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 115.0" "Cell type enhanced" "Detected in all" "Neutrophils: 294.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004548, HPA059156, HPA074031" Supported Supported Nucleoplasm No No 8900 "Cluster 25: Non-specific - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 55: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 63 Nucleoplasm "CAB004548: , HPA059156: , HPA074031: " "unprognostic (4.09e-1)" "unprognostic (7.62e-3)" "unprognostic (1.34e-1)" "unprognostic (7.16e-2)" "unprognostic (3.72e-1)" "unprognostic (1.68e-1)" "unprognostic (4.62e-2)" "unprognostic (4.45e-2)" "unprognostic (1.72e-3)" "unprognostic (1.13e-1)" "unprognostic (1.45e-1)" "unprognostic (3.57e-2)" "potential prognostic unfavorable (1.52e-4)" "validated prognostic unfavorable (5.74e-6)" "validated prognostic unfavorable (4.85e-5)" "unprognostic (2.31e-2)" "potential prognostic unfavorable (5.49e-5)" "unprognostic (1.78e-1)" "unprognostic (2.66e-2)" "unprognostic (1.68e-1)" "unprognostic (7.45e-2)" "unprognostic (2.50e-2)" "unprognostic (1.27e-3)" "unprognostic (3.04e-2)" "unprognostic (9.16e-2)" "unprognostic (1.13e-1)" "unprognostic (5.49e-2)" "unprognostic (2.38e-1)" "unprognostic (9.41e-2)" "unprognostic (1.76e-2)" "unprognostic (2.45e-1)" JMJD7 ENSG00000243789 "Jumonji domain containing 7" P0C870 15 41828092-41837581 "Enzymes, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Monooxygenase, Oxidoreductase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 1.7;Bergmann glia: 2.0;Brain excitatory neurons: 5.8;Brain inhibitory neurons: 3.6;Choroid plexus epithelial cells: 4.5;Early spermatids: 1.2;Ependymal cells: 1.9;Microglia: 4.0;Oligodendrocyte progenitor cells: 3.8;Oligodendrocytes: 3.1;Other brain neurons: 5.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005726 Approved Approved Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 2: Non-specific - Mixed function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 14 Cytosol "HPA005726: " "unprognostic (1.16e-2)" "unprognostic (2.20e-1)" "unprognostic (5.96e-2)" "unprognostic (1.17e-1)" "unprognostic (1.67e-1)" "unprognostic (5.21e-1)" "unprognostic (5.98e-3)" "unprognostic (7.76e-2)" "unprognostic (1.71e-1)" "potential prognostic favorable (8.45e-4)" "unprognostic (2.85e-2)" "potential prognostic favorable (6.52e-5)" "unprognostic (4.49e-2)" "potential prognostic favorable (1.84e-4)" "unprognostic (1.82e-3)" "unprognostic (2.00e-1)" "unprognostic (9.06e-2)" "unprognostic (7.38e-2)" "unprognostic (6.16e-2)" "unprognostic (5.06e-2)" "unprognostic (8.26e-2)" "unprognostic (4.00e-2)" "unprognostic (3.75e-1)" "unprognostic (1.84e-1)" "unprognostic (3.18e-1)" "unprognostic (9.56e-2)" "unprognostic (7.09e-2)" "unprognostic (9.01e-2)" "unprognostic (2.85e-2)" "unprognostic (2.17e-1)" JMJD7-PLA2G4B ENSG00000168970 "JMJD7-PLA2G4B readthrough" 15 41828095-41848155 "Predicted intracellular proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.4;Epicardial cells: 4.5;Epididymal basal cells: 1.5;Epididymal efferent duct ciliated cells: 1.7;Esophageal apical cells: 2.8;Gastric chief cells: 3.3;Parietal cells: 1.8;Smooth muscle cells: 2.8" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" HPA005726 Approved Approved Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 49: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 15: Non-specific - Protein processing" Cytosol "HPA005726: " "unprognostic (3.03e-3)" "potential prognostic favorable (1.60e-4)" "unprognostic (7.99e-3)" "unprognostic (4.97e-2)" JMJD8 C16orf20 ENSG00000161999 "Jumonji domain containing 8" Q96S16 16 681670-684528 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 84.5;Esophageal apical cells: 131.7;Late spermatids: 87.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" "No annotated function" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 70: Non-specific - Protein processing" "Cluster 8: Immune cells - Immune response" "Cluster 54: Non-specific - Transcription" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" "unprognostic (8.52e-2)" "unprognostic (4.40e-2)" "unprognostic (2.85e-1)" "unprognostic (3.13e-3)" "unprognostic (3.42e-2)" "unprognostic (3.97e-1)" "unprognostic (4.41e-2)" "unprognostic (1.26e-2)" "unprognostic (4.31e-2)" "unprognostic (2.69e-1)" "unprognostic (6.77e-2)" "unprognostic (4.93e-2)" "potential prognostic favorable (4.73e-7)" "unprognostic (1.80e-1)" "unprognostic (7.94e-2)" "unprognostic (1.44e-2)" "unprognostic (2.92e-1)" "unprognostic (3.09e-2)" "unprognostic (2.75e-1)" "unprognostic (1.24e-1)" "unprognostic (9.76e-2)" "unprognostic (1.68e-1)" "unprognostic (7.09e-3)" "unprognostic (1.36e-2)" "unprognostic (5.36e-2)" "unprognostic (1.82e-1)" "unprognostic (3.50e-1)" "unprognostic (1.28e-2)" "unprognostic (1.88e-1)" "unprognostic (2.73e-1)" "unprognostic (1.71e-1)" JMY "FLJ37870, WHAMM2" ENSG00000152409 "Junction mediating and regulatory protein, p53 cofactor" Q8N9B5 5 79236131-79327211 "Predicted intracellular proteins" "DNA damage, DNA repair" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Innate lymphoid cells: 698.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037508, HPA043308" Uncertain Uncertain Nucleoplasm NA NA "Cluster 61: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 2 Nucleoplasm "HPA037508: , HPA043308: " "unprognostic (3.22e-3)" "unprognostic (5.41e-2)" "unprognostic (1.14e-1)" "unprognostic (2.43e-1)" "unprognostic (3.12e-1)" "unprognostic (2.70e-2)" "unprognostic (2.33e-2)" "unprognostic (3.32e-2)" "unprognostic (1.59e-2)" "unprognostic (4.06e-2)" "potential prognostic favorable (7.10e-5)" "unprognostic (8.91e-2)" "unprognostic (1.39e-1)" "unprognostic (4.51e-2)" "unprognostic (4.87e-2)" "unprognostic (2.15e-1)" "unprognostic (2.52e-3)" "unprognostic (3.61e-2)" "unprognostic (2.66e-2)" "potential prognostic unfavorable (5.56e-4)" "unprognostic (5.06e-3)" "unprognostic (2.37e-1)" "unprognostic (5.13e-2)" "unprognostic (1.45e-1)" "unprognostic (2.54e-2)" "unprognostic (3.57e-2)" "unprognostic (2.52e-1)" "unprognostic (7.90e-2)" "unprognostic (2.68e-1)" "unprognostic (9.23e-2)" "unprognostic (2.98e-1)" JOSD1 KIAA0063 ENSG00000100221 "Josephin domain containing 1" Q15040 22 38685543-38701556 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 402.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001168, CAB034927" Uncertain Approved Vesicles,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 15: Bone marrow - Innate immune response" "Cluster 34: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 28 "Vesicles, Cytosol" "CAB034927: , HPA001168: " "unprognostic (1.88e-1)" "unprognostic (4.02e-2)" "unprognostic (1.82e-1)" "unprognostic (1.62e-1)" "unprognostic (1.49e-2)" "unprognostic (3.49e-1)" "unprognostic (1.11e-1)" "unprognostic (2.60e-2)" "unprognostic (1.01e-1)" "unprognostic (1.65e-1)" "potential prognostic favorable (4.05e-4)" "unprognostic (6.13e-3)" "unprognostic (2.12e-2)" "potential prognostic unfavorable (7.63e-5)" "unprognostic (3.91e-3)" "unprognostic (5.61e-3)" "unprognostic (4.73e-3)" "unprognostic (3.80e-2)" "unprognostic (3.12e-3)" "unprognostic (2.79e-1)" "unprognostic (6.18e-2)" "unprognostic (8.08e-3)" "unprognostic (5.31e-1)" "unprognostic (1.35e-1)" "potential prognostic favorable (2.11e-4)" "unprognostic (1.32e-2)" "unprognostic (8.70e-2)" "unprognostic (7.53e-2)" "unprognostic (7.45e-2)" "unprognostic (3.75e-2)" "unprognostic (1.45e-1)" JOSD2 SBBI54 ENSG00000161677 "Josephin domain containing 2" Q8TAC2 19 50505998-50511220 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 191.0;Enterocytes: 142.3;Esophageal apical cells: 265.0;Esophageal suprabasal cells: 226.9;Respiratory ciliated cells: 139.8" "Cell type enhanced" "Detected in all" "oligodendrocyte: 55.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 17 "unprognostic (3.53e-2)" "unprognostic (1.30e-1)" "unprognostic (1.30e-2)" "unprognostic (1.24e-3)" "unprognostic (3.25e-1)" "unprognostic (1.37e-1)" "unprognostic (1.46e-2)" "unprognostic (7.40e-3)" "unprognostic (2.80e-1)" "unprognostic (7.95e-2)" "unprognostic (1.56e-2)" "potential prognostic unfavorable (3.21e-4)" "unprognostic (3.64e-2)" "potential prognostic unfavorable (9.04e-5)" "unprognostic (1.70e-3)" "unprognostic (1.90e-3)" "unprognostic (2.68e-1)" "unprognostic (1.65e-1)" "unprognostic (1.25e-1)" "unprognostic (4.32e-3)" "unprognostic (8.59e-2)" "unprognostic (2.81e-2)" "unprognostic (5.98e-2)" "unprognostic (1.90e-1)" "unprognostic (8.09e-2)" "unprognostic (2.41e-1)" "unprognostic (2.38e-1)" "unprognostic (8.78e-2)" "unprognostic (1.61e-1)" "unprognostic (5.02e-2)" "unprognostic (1.79e-1)" JPH1 JP-1 ENSG00000104369 "Junctophilin 1" Q9HDC5 8 74234700-74321540 "Human disease related genes, Predicted membrane proteins, Transporters" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "skeletal muscle: 222.3;tongue: 99.1" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 106.2;Choroid plexus epithelial cells: 315.7;Myonuclei: 681.0;Pancreatic acinar cells: 78.6;Thymic myoid cells: 191.7;Urothelial cells: 88.8" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 333.2;hippocampal dentate gyrus: 295.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Podocytes, Pituitary gland - Corticotropes, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008996, HPA009413, CAB013461" Enhanced Enhanced Nucleoplasm NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 31: Non-specific - Transcription" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 24 Nucleoplasm "CAB013461: , HPA008996: , HPA009413: " "unprognostic (8.26e-2)" "unprognostic (1.84e-3)" "unprognostic (1.72e-1)" "unprognostic (2.01e-1)" "unprognostic (6.03e-2)" "unprognostic (4.62e-2)" "unprognostic (2.82e-1)" "unprognostic (8.46e-2)" "unprognostic (3.71e-1)" "unprognostic (2.44e-2)" "unprognostic (1.63e-2)" "unprognostic (3.01e-1)" "potential prognostic favorable (1.55e-4)" "unprognostic (3.47e-1)" "unprognostic (2.73e-1)" "unprognostic (2.17e-1)" "unprognostic (3.66e-1)" "unprognostic (2.33e-1)" "unprognostic (4.57e-2)" "unprognostic (6.68e-2)" "unprognostic (9.54e-2)" "unprognostic (6.47e-2)" "unprognostic (8.15e-2)" "unprognostic (1.06e-1)" "unprognostic (1.32e-2)" JPH2 JP-2 ENSG00000149596 "Junctophilin 2" Q9BR39 20 44106590-44187188 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 112.8" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 49.1;Cardiomyocytes: 138.3;Myonuclei: 387.4;Myosatellite cells: 93.1;Salivary myoepithelial cells: 101.1;Smooth muscle cells: 263.6;Thymic myoid cells: 225.7;Vascular smooth muscle cells: 152.2" "Cell type enriched" "Detected in many" 10 "vascular associated smooth muscle cell: 176.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Colon - Smooth muscle cells, Heart muscle - Cardiomyocytes, Kidney - Fibroblasts, Lung - Smooth muscle cells, Minor Salivary Gland - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Skin - Smooth muscle cells, Spleen - Smooth muscle cells, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in some" HPA052646 Approved NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 62: Smooth muscle cells - Muscle contraction" 2 "HPA052646: " "unprognostic (5.86e-2)" "unprognostic (7.64e-2)" "unprognostic (3.27e-1)" "unprognostic (1.04e-1)" "unprognostic (6.13e-2)" "unprognostic (3.34e-2)" "unprognostic (2.29e-1)" "unprognostic (1.80e-2)" "unprognostic (2.53e-2)" "potential prognostic unfavorable (1.48e-4)" "unprognostic (9.21e-2)" "unprognostic (4.56e-2)" "unprognostic (2.67e-3)" "unprognostic (1.83e-3)" "unprognostic (1.64e-2)" "unprognostic (2.06e-2)" "unprognostic (2.45e-2)" "unprognostic (2.11e-2)" "unprognostic (8.81e-3)" "unprognostic (1.80e-2)" "unprognostic (2.32e-1)" "unprognostic (3.88e-2)" JPH3 "CAGL237, HDL2, JP-3, JP3, TNRC22" ENSG00000154118 "Junctophilin 3" Q8WXH2 16 87601835-87698156 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "brain: 112.1" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 31.9;Brain excitatory neurons: 62.5;Brain inhibitory neurons: 47.8;Cone photoreceptor cells: 39.3;Early spermatids: 62.8;Gonadotrophs: 22.9;Lactotrophs: 25.4;Oligodendrocyte progenitor cells: 21.7;Oocytes: 50.7;Other brain neurons: 49.2;Retinal amacrine cells: 51.5;Retinal bipolar cells: 46.3;Retinal horizontal cells: 42.1;Rod photoreceptor cells: 25.9;Somatotrophs: 30.5;Thyrotrophs: 25.5" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 3.6;Ovary Serous Cystadenocarcinoma (TCGA): 5.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 5.8;Neuroblastoma: 6.1" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in all" HPA076304 Approved Nucleoplasm,Cytosol Yes No "Cluster 10: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 146 Nucleoplasm Cytosol "HPA076304: " "unprognostic (1.39e-1)" "unprognostic (3.12e-1)" "potential prognostic favorable (4.26e-4)" "unprognostic (2.45e-1)" "unprognostic (7.48e-3)" "unprognostic (2.08e-1)" JPH4 "JPHL1, KIAA1831" ENSG00000092051 "Junctophilin 4" Q96JJ6 14 23568038-23578790 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 136.2;pituitary gland: 54.0" "Cell type enhanced" "Detected in many" "Bergmann glia: 122.6;Brain excitatory neurons: 130.6;Brain inhibitory neurons: 151.2;Corticotrophs: 81.7;Gonadotrophs: 75.6;Lactotrophs: 108.4;Oligodendrocyte progenitor cells: 58.6;Other brain neurons: 91.0;Retinal amacrine cells: 396.3;Retinal bipolar cells: 104.1;Retinal ganglion cells: 96.6;Retinal horizontal cells: 368.6;Somatotrophs: 77.0;Thyrotrophs: 130.7" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 16.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.7;myeloid DC: 3.1" "Group enriched" "Detected in many" 8 "dendritic cells: 3.1;monocytes: 2.7" "Cancer enriched" "Detected in some" 5 "Neuroblastoma: 43.0" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pituitary gland - Lactotropes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045022 Approved Cytosol NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 2 Cytosol "HPA045022: " "unprognostic (1.96e-1)" "unprognostic (5.09e-1)" "potential prognostic favorable (1.14e-4)" "validated prognostic favorable (2.07e-9)" "validated prognostic favorable (2.49e-4)" "unprognostic (3.83e-2)" "unprognostic (2.58e-3)" "unprognostic (3.15e-2)" "unprognostic (1.92e-1)" "unprognostic (8.89e-2)" JPT1 "ARM2, HN1, HN1A" ENSG00000189159 "Jupiter microtubule associated homolog 1" Q9UK76 17 75135248-75168281 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 394.7" "Cell type enhanced" "Detected in many" "Early spermatids: 1314.5;Esophageal apical cells: 1438.3;Esophageal suprabasal cells: 1069.5;Extravillous trophoblasts: 2151.7;Gastric progenitor cells: 975.4;Late primary spermatocytes: 2043.7;Late spermatids: 1773.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 773.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011097, HPA059729, HPA076731" Approved Supported "Nucleoplasm,Microtubules,Cytokinetic bridge,Cytosol" Yes NA 41000 "Cluster 7: Non-specific - Innate immune response" "Cluster 39: Testis - Nuclear processes" "Cluster 1: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 9 Cytosol "Nucleoplasm, Microtubules, Cytokinetic bridge" "HPA011097: , HPA059729: , HPA076731: " "unprognostic (1.88e-3)" "unprognostic (5.97e-3)" "unprognostic (1.67e-1)" "potential prognostic favorable (7.89e-4)" "unprognostic (2.90e-1)" "unprognostic (8.84e-2)" "unprognostic (3.28e-3)" "potential prognostic unfavorable (1.40e-4)" "unprognostic (8.16e-3)" "validated prognostic unfavorable (2.16e-7)" "validated prognostic unfavorable (6.88e-5)" "unprognostic (2.10e-3)" "potential prognostic unfavorable (5.87e-9)" "unprognostic (3.19e-3)" "unprognostic (6.93e-3)" "unprognostic (1.66e-1)" "unprognostic (9.68e-2)" "unprognostic (1.17e-2)" "unprognostic (3.20e-1)" "unprognostic (3.80e-3)" "unprognostic (2.16e-1)" "unprognostic (3.82e-2)" "unprognostic (9.85e-2)" "unprognostic (1.73e-1)" "unprognostic (7.82e-2)" "unprognostic (2.40e-1)" "unprognostic (5.42e-2)" "unprognostic (1.74e-2)" "unprognostic (6.71e-2)" JPT2 "C16orf34, FLJ13092, HN1L, KIAA1426, L11" ENSG00000206053 "Jupiter microtubule associated homolog 2" Q9H910 16 1678256-1702280 "Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 116.7" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 283.4;Fallopian tube ciliated cells: 133.1;Late spermatids: 223.2;Migrating cytotrophoblasts: 171.0;Respiratory ciliated cells: 162.2;Syncytiotrophoblasts: 220.0" "Cell type enhanced" "Detected in all" "oligodendrocyte: 36.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041888, HPA041908" Enhanced Supported "Plasma membrane,Cytosol" NA NA 97000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 54: Non-specific - Transcription" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." 2 "Plasma membrane, Cytosol" "HPA041888: , HPA041908: " "unprognostic (2.35e-2)" "unprognostic (4.10e-3)" "unprognostic (2.51e-2)" "unprognostic (2.61e-2)" "unprognostic (2.03e-1)" "unprognostic (3.82e-1)" "unprognostic (2.84e-1)" "unprognostic (4.30e-2)" "unprognostic (6.00e-3)" "unprognostic (1.41e-3)" "unprognostic (1.06e-1)" "unprognostic (8.55e-2)" "potential prognostic unfavorable (3.05e-5)" "unprognostic (1.01e-2)" "unprognostic (7.86e-3)" "unprognostic (1.07e-1)" "unprognostic (2.66e-1)" "unprognostic (4.50e-2)" "unprognostic (1.70e-1)" "unprognostic (2.88e-3)" "unprognostic (2.00e-3)" "unprognostic (6.82e-2)" "unprognostic (8.06e-2)" "unprognostic (5.72e-2)" "unprognostic (1.31e-1)" "unprognostic (7.20e-2)" "unprognostic (4.22e-2)" "unprognostic (2.38e-2)" "unprognostic (2.72e-2)" JRK "jerky, JH8" ENSG00000234616 "Jrk helix-turn-helix protein" O75564 8 142657460-142681968 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052675 Approved "Nucleoplasm,Nucleoli,Nuclear bodies" No No "Cluster 41: Basophils - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 68: Foveolar cells - Mucosal defense" 1 "Nucleoplasm, Nucleoli" "Nuclear bodies" "HPA052675: " "unprognostic (1.04e-1)" "unprognostic (6.87e-3)" "unprognostic (6.52e-2)" "unprognostic (4.36e-2)" "unprognostic (3.86e-2)" "unprognostic (2.61e-2)" "unprognostic (2.04e-1)" "potential prognostic favorable (1.71e-4)" "unprognostic (5.51e-2)" "unprognostic (3.26e-2)" "unprognostic (1.02e-3)" "unprognostic (1.16e-3)" "unprognostic (1.14e-1)" "unprognostic (3.92e-3)" "unprognostic (2.73e-1)" "unprognostic (7.81e-2)" "unprognostic (9.64e-2)" "unprognostic (1.28e-1)" "unprognostic (2.78e-1)" "unprognostic (8.85e-3)" "unprognostic (2.79e-1)" "unprognostic (9.41e-2)" "potential prognostic unfavorable (8.42e-4)" "unprognostic (1.18e-1)" "unprognostic (2.47e-1)" "unprognostic (3.71e-2)" "unprognostic (1.80e-1)" "unprognostic (2.34e-1)" "unprognostic (1.61e-1)" "unprognostic (1.06e-2)" "unprognostic (2.28e-1)" JRKL HHMJG ENSG00000183340 "JRK like" Q9Y4A0 11 96389989-96507574 "Plasma proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 327.0;Late primary spermatocytes: 70.6;Late spermatids: 128.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046184, HPA060341" Uncertain Approved "Nucleoplasm,Cytokinetic bridge" Yes No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" Nucleoplasm "Cytokinetic bridge" "HPA046184: , HPA060341: " "unprognostic (3.62e-3)" "unprognostic (5.57e-3)" "unprognostic (3.77e-2)" "unprognostic (3.97e-3)" "unprognostic (3.30e-2)" "unprognostic (3.09e-1)" "unprognostic (6.81e-2)" "unprognostic (9.99e-2)" "unprognostic (2.27e-1)" "unprognostic (2.20e-1)" "potential prognostic favorable (6.84e-4)" "unprognostic (3.70e-2)" "unprognostic (2.72e-2)" "unprognostic (1.32e-3)" "unprognostic (3.29e-1)" "unprognostic (6.64e-3)" "potential prognostic unfavorable (9.22e-4)" "unprognostic (1.22e-1)" "unprognostic (2.29e-1)" "unprognostic (2.73e-2)" "unprognostic (7.10e-2)" "unprognostic (1.85e-2)" "unprognostic (6.74e-2)" "unprognostic (1.17e-1)" "unprognostic (1.84e-2)" "unprognostic (1.28e-1)" "unprognostic (1.52e-2)" "unprognostic (9.46e-2)" "unprognostic (2.66e-1)" "unprognostic (8.49e-2)" "unprognostic (6.34e-2)" JSRP1 "FLJ32416, JP-45" ENSG00000167476 "Junctional sarcoplasmic reticulum protein 1" Q96MG2 19 2252252-2269759 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "skeletal muscle: 325.7" "Group enriched" "Detected in many" 4 "Cardiomyocytes: 210.2;Epicardial cells: 100.1;Myosatellite cells: 112.6;Plasma cells: 282.8;Platelets: 94.6;Thymic myoid cells: 130.5" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 23.9" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 10 "naive B-cell: 2.7" "Lineage enriched" "Detected in single" 10 "B-cells: 2.7" "Cancer enriched" "Detected in many" 6 "Myeloma: 154.3" "Adipose visceral - Plasma cells, Breast - Plasma cells, Lung - Plasma cells, Pancreas - Alpha cells, Spleen - Plasma cells, Stomach - Plasma cells, Testis - Late spermatids" "Group enriched" "Detected in many" 6 "amygdala: 8.4;basal ganglia: 11.6;cerebral cortex: 9.9;hippocampal formation: 4.4;white matter: 5.1" "Not detected" "Not detected" HPA044741 Enhanced Approved "Endoplasmic reticulum" NA NA 21000 "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 67: Plasma cells - Plasma cell differentiation" 7 "Endoplasmic reticulum" "HPA044741: " "unprognostic (1.92e-1)" "unprognostic (1.18e-2)" "unprognostic (5.87e-2)" "unprognostic (6.15e-3)" "unprognostic (2.76e-1)" "unprognostic (9.84e-2)" "unprognostic (4.16e-2)" "unprognostic (1.18e-3)" "potential prognostic unfavorable (7.29e-7)" "unprognostic (4.13e-3)" "unprognostic (8.18e-2)" "unprognostic (3.93e-2)" "unprognostic (4.50e-2)" "unprognostic (1.29e-1)" "unprognostic (1.70e-2)" "unprognostic (4.11e-2)" "unprognostic (1.90e-1)" "unprognostic (5.50e-2)" "unprognostic (1.57e-1)" "unprognostic (2.18e-1)" "unprognostic (6.42e-2)" "unprognostic (2.56e-1)" "unprognostic (5.25e-1)" "unprognostic (1.91e-1)" "unprognostic (4.05e-1)" JTB "hJT, PAR" ENSG00000143543 "Jumping translocation breakpoint" O76095 1 153974269-153977674 "Cancer-related genes, Plasma proteins, Predicted membrane proteins" "Apoptosis, Cell cycle, Cell division, Mitosis" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric chief cells: 208.6;Parietal cells: 139.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Somatotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006514 Approved Approved Vesicles,Mitochondria NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 7: Non-specific - Ribosome" "Cluster 45: Non-specific - Nuclear processes" "Cluster 67: Plasma cells - Plasma cell differentiation" 2 "Vesicles, Mitochondria" "HPA006514: " "unprognostic (2.15e-1)" "unprognostic (1.26e-1)" "unprognostic (6.54e-2)" "unprognostic (9.02e-2)" "unprognostic (1.32e-1)" "unprognostic (1.05e-1)" "unprognostic (1.95e-2)" "unprognostic (7.42e-2)" "unprognostic (1.14e-1)" "unprognostic (4.10e-3)" "unprognostic (2.98e-3)" "unprognostic (1.51e-3)" "unprognostic (4.43e-3)" "potential prognostic unfavorable (5.02e-5)" "unprognostic (1.19e-2)" "unprognostic (3.69e-1)" "unprognostic (8.32e-2)" "unprognostic (5.59e-2)" "unprognostic (4.20e-2)" "unprognostic (1.66e-2)" "unprognostic (2.55e-1)" "unprognostic (8.88e-3)" "unprognostic (1.15e-2)" "unprognostic (8.76e-2)" "unprognostic (7.69e-2)" "unprognostic (3.24e-3)" "unprognostic (3.32e-2)" "unprognostic (1.29e-1)" "unprognostic (8.52e-2)" "unprognostic (6.94e-3)" "unprognostic (3.31e-2)" JUN "AP-1, c-Jun" ENSG00000177606 "Jun proto-oncogene, AP-1 transcription factor subunit" P05412 1 58776845-58784048 "Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Breast lactating cells: 3947.7;Epididymal principal cells: 3795.9;Ovarian stromal cells: 4609.4;Pancreatic duct cells: 3632.0" "Cell type enhanced" "Detected in all" "astrocyte: 239.9;endothelial cell: 299.8;vascular associated smooth muscle cell: 260.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003801, CAB007780, HPA059474, HPA066898, CAB080216, CAB080219, CAB080220" Enhanced Enhanced Nucleoplasm Yes No "Cluster 14: Non-specific - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 72: Neuronal - Signal transduction" "Cluster 20: Non-specific - Transcription regulation" 202 Nucleoplasm "CAB003801: , CAB007780: , CAB080216: , CAB080219: , CAB080220: , HPA059474: , HPA066898: " "unprognostic (1.36e-2)" "unprognostic (9.79e-2)" "unprognostic (8.33e-2)" "unprognostic (4.53e-2)" "unprognostic (3.67e-2)" "unprognostic (2.01e-2)" "unprognostic (1.54e-1)" "unprognostic (3.08e-1)" "unprognostic (2.91e-2)" "unprognostic (1.27e-1)" "potential prognostic favorable (3.22e-4)" "unprognostic (2.36e-1)" "unprognostic (2.68e-2)" "unprognostic (1.81e-3)" "unprognostic (2.71e-2)" "unprognostic (2.26e-1)" "unprognostic (1.31e-1)" "unprognostic (2.39e-2)" "unprognostic (3.61e-1)" "unprognostic (1.59e-2)" "unprognostic (1.44e-1)" "unprognostic (1.39e-1)" "unprognostic (3.81e-1)" "unprognostic (3.14e-1)" "unprognostic (1.36e-1)" "unprognostic (1.31e-2)" "unprognostic (2.01e-1)" "unprognostic (2.48e-2)" "unprognostic (4.66e-1)" "unprognostic (1.15e-1)" "unprognostic (1.39e-1)" JUNB ENSG00000171223 "JunB proto-oncogene, AP-1 transcription factor subunit" P17275 19 12791486-12793315 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 1053.5" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 5566.7;Esophageal apical cells: 4764.5;Neutrophils: 3351.6;Ovarian stromal cells: 5401.2;Smooth muscle cells: 3169.9;Vascular smooth muscle cells: 3221.2" "Cell type enhanced" "Detected in all" "endothelial cell: 222.9;vascular associated smooth muscle cell: 627.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 681.7" "Group enriched" "Detected in all" 5 "granulocytes: 681.7;monocytes: 182.7" "Low cancer specificity" "Detected in all" "Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004464, HPA019149" Approved Supported Nucleoplasm NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 74: Non-specific - Signal transduction" "Cluster 44: Non-specific - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 20: Non-specific - Transcription regulation" 63 Nucleoplasm "CAB004464: , HPA019149: " "unprognostic (2.17e-3)" "unprognostic (1.71e-3)" "unprognostic (6.82e-3)" "unprognostic (3.57e-2)" "unprognostic (3.66e-2)" "unprognostic (1.15e-1)" "unprognostic (9.42e-2)" "unprognostic (5.34e-2)" "unprognostic (6.12e-2)" "unprognostic (7.75e-2)" "unprognostic (5.95e-2)" "unprognostic (1.57e-2)" "unprognostic (1.48e-1)" "unprognostic (2.65e-1)" "unprognostic (9.05e-3)" "unprognostic (1.46e-2)" "unprognostic (1.21e-1)" "unprognostic (2.92e-2)" "unprognostic (1.12e-1)" "potential prognostic unfavorable (9.48e-5)" "unprognostic (1.58e-1)" "unprognostic (2.07e-1)" "unprognostic (2.27e-1)" "unprognostic (4.37e-2)" "unprognostic (2.11e-1)" "unprognostic (9.12e-3)" "unprognostic (2.09e-1)" "unprognostic (1.01e-1)" "unprognostic (8.12e-2)" "unprognostic (2.82e-1)" "unprognostic (2.24e-1)" JUND AP-1 ENSG00000130522 "JunD proto-oncogene, AP-1 transcription factor subunit" P17535 19 18279694-18281622 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Innate lymphoid cells: 2148.7;Mast cells: 1959.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005268, HPA063029, HPA068905" Supported Enhanced Nucleoplasm No No "Cluster 7: Non-specific - Innate immune response" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 20: Non-specific - Transcription regulation" 35 Nucleoplasm "CAB005268: , HPA063029: , HPA068905: " "unprognostic (7.21e-3)" "potential prognostic favorable (8.05e-4)" "unprognostic (7.91e-2)" "unprognostic (1.50e-1)" "unprognostic (2.42e-2)" "unprognostic (1.15e-1)" "unprognostic (1.90e-1)" "unprognostic (8.35e-2)" "unprognostic (2.31e-2)" "unprognostic (6.72e-2)" "unprognostic (1.15e-1)" "unprognostic (3.38e-2)" "unprognostic (8.93e-2)" "unprognostic (1.24e-2)" "unprognostic (1.85e-1)" "unprognostic (2.17e-1)" "unprognostic (2.11e-2)" "unprognostic (1.59e-2)" "unprognostic (2.40e-2)" "unprognostic (1.17e-1)" "unprognostic (5.29e-2)" "unprognostic (4.38e-3)" "unprognostic (2.08e-2)" "unprognostic (1.67e-1)" "unprognostic (4.51e-2)" "potential prognostic favorable (7.75e-6)" "unprognostic (2.99e-1)" "unprognostic (1.29e-1)" "unprognostic (1.29e-1)" "unprognostic (1.69e-2)" "unprognostic (6.58e-2)" JUP "CTNNG, DP3, DPIII, PDGB, PG, PKGB" ENSG00000173801 "Junction plakoglobin" P14923 17 41754604-41786931 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Cancer-related genes, Cardiomyopathy, Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 914.3;skin 1: 886.7" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 2248.1;Esophageal basal cells: 688.2;Esophageal suprabasal cells: 1555.8;Ocular epithelial cells: 617.7;Suprabasal keratinocytes: 998.3;Urothelial cells: 525.0" "Cell type enhanced" "Detected in many" "Bergmann glia: 36.7;fibroblast: 44.6;pericyte: 38.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 13.2;eosinophil: 28.8;intermediate monocyte: 22.6;memory B-cell: 13.5;myeloid DC: 14.6;naive B-cell: 11.7;non-classical monocyte: 44.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Lung - Alveolar cells type 1, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002139, HPA032047" Supported Supported "Vesicles,Plasma membrane,Cell Junctions" NA NA 61000000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 78 "Plasma membrane, Cell Junctions" Vesicles "CAB002139: , HPA032047: " "unprognostic (1.20e-1)" "unprognostic (3.23e-3)" "unprognostic (5.99e-2)" "unprognostic (1.03e-1)" "unprognostic (1.12e-1)" "unprognostic (6.25e-2)" "unprognostic (4.77e-2)" "unprognostic (2.88e-2)" "unprognostic (9.80e-2)" "unprognostic (1.36e-1)" "validated prognostic favorable (3.52e-8)" "validated prognostic favorable (3.75e-4)" "unprognostic (3.24e-2)" "unprognostic (2.80e-1)" "potential prognostic unfavorable (4.87e-5)" "unprognostic (1.41e-2)" "unprognostic (1.72e-1)" "unprognostic (2.02e-1)" "unprognostic (2.60e-1)" "unprognostic (4.75e-3)" "unprognostic (1.29e-1)" "unprognostic (2.49e-3)" "unprognostic (1.47e-2)" "unprognostic (1.83e-1)" "unprognostic (2.17e-2)" "unprognostic (1.70e-2)" "unprognostic (1.20e-2)" "unprognostic (1.35e-1)" "unprognostic (1.15e-1)" "unprognostic (1.46e-1)" "unprognostic (1.50e-1)" KALRN "ARHGEF24, DUET, duo, HAPIP, Hs.8004, Kalirin, TRAD" ENSG00000160145 "Kalirin RhoGEF kinase" O60229 3 124033369-124726325 "Cancer-related genes, Enzymes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Guanine-nucleotide releasing factor, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 40.4" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 972.0;Brain inhibitory neurons: 697.8;Gonadotrophs: 812.9;Lymphatic endothelial cells: 1324.3;Peritubular myoid cells: 539.3;Vascular endothelial cells: 529.1;Vascular smooth muscle cells: 542.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.7" "Lineage enriched" "Detected in single" 6 "T-cells: 1.7" "Low cancer specificity" "Detected in many" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "HPA011913, CAB026456" Approved Approved Nucleoplasm,Cytosol NA NA 45000 "Cluster 25: Non-specific - Basic cellular processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 4 "Nucleoplasm, Cytosol" "CAB026456: , HPA011913: " "unprognostic (2.11e-1)" "unprognostic (1.94e-2)" "unprognostic (1.88e-1)" "unprognostic (7.86e-2)" "unprognostic (9.66e-2)" "unprognostic (9.37e-2)" "unprognostic (1.85e-1)" "unprognostic (5.12e-2)" "unprognostic (1.96e-1)" "unprognostic (3.03e-2)" "potential prognostic favorable (2.92e-7)" "unprognostic (2.86e-2)" "unprognostic (1.54e-1)" "unprognostic (2.66e-2)" "unprognostic (1.11e-1)" "unprognostic (1.77e-1)" "unprognostic (7.13e-2)" "unprognostic (1.21e-2)" "unprognostic (7.97e-2)" "unprognostic (1.35e-1)" "unprognostic (2.30e-2)" "unprognostic (1.98e-1)" "unprognostic (4.27e-3)" "unprognostic (1.63e-1)" "unprognostic (1.24e-2)" "unprognostic (1.26e-2)" "unprognostic (4.43e-2)" "unprognostic (9.62e-2)" "unprognostic (2.46e-1)" "unprognostic (2.54e-3)" "unprognostic (2.19e-1)" KANK1 "ANKRD15, KANK, KIAA0172" ENSG00000107104 "KN motif and ankyrin repeat domains 1" Q14678 9 470291-746105 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 1717.9;Cytotrophoblasts: 1022.3;Distal convoluted tubule cells: 1880.8;Pituitary stem cells: 3107.4;Podocytes: 2505.6" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 1361.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 3.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005539, HPA056090" Approved Supported "Plasma membrane" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 76: Non-specific - Metabolism" "Cluster 8: Immune cells - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 57: Podocytes - Glomerular filtration" 17 "Plasma membrane" "HPA005539: , HPA056090: " "unprognostic (1.62e-1)" "unprognostic (1.55e-1)" "unprognostic (1.00e-1)" "unprognostic (1.19e-1)" "unprognostic (6.86e-2)" "unprognostic (1.08e-1)" "unprognostic (2.15e-1)" "unprognostic (1.11e-1)" "unprognostic (1.26e-1)" "unprognostic (3.47e-1)" "unprognostic (1.01e-3)" "unprognostic (7.10e-2)" "unprognostic (3.66e-2)" "unprognostic (4.05e-1)" "unprognostic (2.35e-1)" "unprognostic (9.02e-3)" "unprognostic (5.63e-2)" "unprognostic (1.97e-1)" "unprognostic (5.16e-2)" "unprognostic (9.73e-2)" "unprognostic (4.50e-2)" "unprognostic (5.68e-3)" "unprognostic (1.76e-1)" "unprognostic (1.91e-1)" "unprognostic (2.47e-1)" "unprognostic (3.14e-1)" "unprognostic (1.39e-1)" "unprognostic (1.99e-1)" "unprognostic (3.14e-2)" "unprognostic (2.47e-1)" "unprognostic (3.64e-2)" KANK2 "ANKRD25, KIAA1518, MXRA3" ENSG00000197256 "KN motif and ankyrin repeat domains 2" Q63ZY3 19 11164270-11197791 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 139.1;Endometrial stromal cells: 140.6;Hepatic stellate cells: 129.1;Leydig cells: 148.4;Myosatellite cells: 121.4;Ovarian stromal cells: 135.5;Pericytes: 146.8;Peritubular myoid cells: 270.3;Smooth muscle cells: 367.9;Vascular smooth muscle cells: 259.1" "Group enriched" "Detected in many" 5 "fibroblast: 189.1;pericyte: 158.1;vascular associated smooth muscle cell: 186.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015643 Approved Approved Nucleoplasm,Cytosol NA Yes "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 19: Astrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 62: Smooth muscle cells - Muscle contraction" 168 Nucleoplasm Cytosol "HPA015643: " "unprognostic (1.75e-3)" "unprognostic (6.24e-2)" "unprognostic (1.36e-1)" "unprognostic (2.04e-1)" "unprognostic (1.13e-1)" "unprognostic (1.89e-1)" "unprognostic (1.20e-1)" "unprognostic (2.58e-2)" "unprognostic (1.19e-2)" "unprognostic (9.76e-3)" "potential prognostic favorable (3.81e-4)" "unprognostic (3.96e-3)" "unprognostic (2.97e-1)" "unprognostic (3.14e-1)" "unprognostic (5.38e-3)" "unprognostic (7.88e-2)" "unprognostic (9.85e-2)" "unprognostic (4.44e-2)" "unprognostic (2.09e-1)" "unprognostic (2.33e-1)" "unprognostic (1.45e-2)" "unprognostic (1.21e-1)" "unprognostic (1.80e-1)" "unprognostic (3.91e-2)" "unprognostic (4.71e-2)" "unprognostic (6.39e-3)" "unprognostic (1.40e-2)" "unprognostic (1.53e-2)" "unprognostic (5.19e-1)" "unprognostic (1.84e-1)" "unprognostic (1.83e-1)" KANK3 "ANKRD47, FLJ46061" ENSG00000186994 "KN motif and ankyrin repeat domains 3" Q6NY19 19 8322584-8343262 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Lymphatic endothelial cells: 245.2;Vascular endothelial cells: 151.5" "Group enriched" "Detected in many" 5 "endothelial cell: 181.6;pericyte: 146.5" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 15.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 1.2" "Group enriched" "Detected in many" 5 "NK-cells: 1.2;T-cells: 1.0" "Cancer enhanced" "Detected in some" "Rhabdoid: 5.3" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells, Thyroid gland - Endothelial cells" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "olfactory bulb: 21.8" HPA051153 Approved Approved "Plasma membrane" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "Plasma membrane" "HPA051153: " "unprognostic (3.82e-1)" "unprognostic (1.84e-1)" "unprognostic (2.57e-2)" "unprognostic (3.94e-2)" "unprognostic (5.97e-3)" "unprognostic (2.30e-1)" "unprognostic (2.43e-1)" "unprognostic (8.14e-2)" "unprognostic (2.69e-3)" "unprognostic (6.36e-3)" "validated prognostic favorable (1.99e-7)" "validated prognostic favorable (1.09e-4)" "unprognostic (1.60e-3)" "unprognostic (1.67e-3)" "potential prognostic favorable (9.44e-6)" "unprognostic (4.14e-2)" "unprognostic (1.91e-1)" "unprognostic (7.23e-3)" "unprognostic (4.65e-2)" "unprognostic (1.48e-2)" "unprognostic (9.07e-2)" "unprognostic (1.87e-1)" "unprognostic (1.58e-1)" "unprognostic (5.18e-3)" "unprognostic (2.29e-1)" "unprognostic (1.76e-2)" "unprognostic (1.72e-1)" "unprognostic (3.44e-1)" "unprognostic (9.43e-2)" KANK4 "ANKRD38, KIAA0172" ENSG00000132854 "KN motif and ankyrin repeat domains 4" Q5T7N3 1 62236165-62319434 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 10.1;brain: 9.2;pancreas: 12.7;placenta: 10.1" "Cell type enhanced" "Detected in many" "Adipocytes: 109.1;Breast myoepithelial cells: 44.8;Cytotrophoblasts: 197.5;Extravillous trophoblasts: 103.5;Lacrimal acinar cells: 106.9;Migrating cytotrophoblasts: 92.1;Mucous neck cells: 44.3;Pancreatic acinar cells: 52.4;Retinal ganglion cells: 42.5;Salivary myoepithelial cells: 38.4;Schwann cells: 67.3" "Cell type enhanced" "Detected in many" "lower rhombic lip: 80.9;oligodendrocyte: 68.5" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 11.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 18.8;testis cancer: 25.0" "Colon - Enteric glia cells, Liver - Hepatocytes, Testis - Peritubular cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA014030 Uncertain Uncertain Microtubules,Cytosol NA NA "Cluster 60: Stomach - Digestion" "Cluster 49: Hindbrain - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 7 Cytosol Microtubules "HPA014030: " "unprognostic (4.07e-2)" "unprognostic (1.23e-2)" "unprognostic (1.28e-2)" "unprognostic (1.95e-2)" "unprognostic (4.59e-2)" "unprognostic (1.51e-2)" "unprognostic (2.37e-1)" "unprognostic (1.49e-2)" "unprognostic (1.33e-3)" "unprognostic (6.80e-3)" "unprognostic (1.24e-1)" "unprognostic (4.35e-2)" "unprognostic (2.30e-3)" "unprognostic (1.14e-1)" "unprognostic (9.12e-3)" "unprognostic (1.91e-1)" "unprognostic (3.74e-1)" KANSL1 "CENP-36, DKFZP727C091, KIAA1267, MSL1v1, NSL1" ENSG00000120071 "KAT8 regulatory NSL complex subunit 1" Q7Z3B3 17 46029916-46225389 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Chromatin regulator" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 466.3;Bergmann glia: 542.1;Brain excitatory neurons: 455.9;Brain inhibitory neurons: 448.5;Choroid plexus epithelial cells: 976.6;Distal convoluted tubule cells: 550.0;Ependymal cells: 642.6;Loop of henle epithelial cells: 515.3;Microglia: 790.8;Oligodendrocyte progenitor cells: 621.2;Oligodendrocytes: 660.0;Other brain neurons: 352.0;Papillary tip epithelial cells: 449.6;Podocytes: 417.1;Proximal tubule cells: 463.7;Renal collecting duct intercalated cells: 509.4;Renal collecting duct principal cells: 519.6;Renal connecting tubule cells: 515.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006874, HPA007208" Approved Supported Nucleoplasm No No "Cluster 24: Non-specific - Transcription" "Cluster 39: Testis - Nuclear processes" "Cluster 2: Neurons - Nucleosome" "Cluster 27: Breast cancer - Unknown function" "Cluster 102: Non-specific - Mixed function" 51 Nucleoplasm "HPA006874: , HPA007208: " "unprognostic (8.93e-2)" "unprognostic (2.77e-1)" "unprognostic (2.69e-1)" "unprognostic (5.99e-2)" "potential prognostic unfavorable (8.42e-4)" "unprognostic (8.55e-2)" "unprognostic (9.72e-2)" "unprognostic (9.23e-2)" "unprognostic (2.64e-1)" "potential prognostic favorable (1.84e-4)" "unprognostic (3.17e-2)" "unprognostic (4.95e-2)" "unprognostic (6.45e-2)" "unprognostic (1.81e-1)" "unprognostic (1.71e-1)" "unprognostic (4.29e-2)" "unprognostic (3.19e-2)" "unprognostic (1.76e-1)" "unprognostic (4.78e-3)" "unprognostic (2.73e-2)" "potential prognostic unfavorable (3.40e-4)" "unprognostic (5.22e-2)" "unprognostic (1.79e-2)" "unprognostic (2.21e-2)" "unprognostic (3.20e-2)" "unprognostic (2.49e-1)" "unprognostic (3.99e-2)" "unprognostic (2.23e-2)" "unprognostic (2.95e-2)" KANSL1L "C2orf67, FLJ23861, FLJ32349, KIAA1267L, MSL1v2" ENSG00000144445 "KAT8 regulatory NSL complex subunit 1 like" A0AUZ9 2 210021421-210171409 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 8 "parathyroid gland: 187.0" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043102, HPA046790" Uncertain Approved Cytosol NA NA "Cluster 69: Parathyroid gland - Mixed function" "Cluster 55: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 108: Fibroblasts - ECM organization" Cytosol "HPA043102: , HPA046790: " "unprognostic (3.28e-1)" "unprognostic (4.34e-2)" "unprognostic (2.92e-2)" "unprognostic (4.12e-3)" "unprognostic (4.82e-2)" "unprognostic (3.88e-2)" "unprognostic (3.28e-2)" "unprognostic (2.41e-3)" "unprognostic (1.77e-1)" "potential prognostic favorable (3.00e-5)" "unprognostic (8.75e-3)" "unprognostic (2.54e-2)" "unprognostic (4.72e-2)" "unprognostic (9.07e-2)" "unprognostic (3.52e-1)" "unprognostic (8.17e-3)" "unprognostic (9.70e-2)" "unprognostic (2.54e-1)" "unprognostic (3.12e-1)" "unprognostic (1.69e-2)" "unprognostic (3.21e-1)" "unprognostic (5.35e-2)" "unprognostic (2.85e-2)" "unprognostic (5.15e-1)" "unprognostic (1.98e-2)" "unprognostic (1.35e-1)" "unprognostic (3.58e-2)" "unprognostic (8.21e-2)" "unprognostic (2.05e-3)" KANSL2 "C12orf41, FLJ20436, NSL2" ENSG00000139620 "KAT8 regulatory NSL complex subunit 2" Q9H9L4 12 48653211-48682238 "Essential proteins, Predicted intracellular proteins" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038497, HPA038498" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" Other NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 20: Non-specific - Transcription regulation" 13 "Nucleoplasm, Plasma membrane, Cytosol" "HPA038497: , HPA038498: " "unprognostic (2.86e-1)" "unprognostic (7.62e-3)" "unprognostic (6.81e-2)" "unprognostic (1.22e-1)" "unprognostic (1.44e-1)" "unprognostic (9.16e-2)" "unprognostic (5.67e-2)" "unprognostic (2.24e-1)" "unprognostic (1.90e-3)" "potential prognostic favorable (1.35e-4)" "unprognostic (1.54e-2)" "unprognostic (4.87e-1)" "unprognostic (2.53e-2)" "unprognostic (3.28e-2)" "unprognostic (6.39e-3)" "unprognostic (1.55e-1)" "unprognostic (6.33e-2)" "unprognostic (4.57e-1)" "unprognostic (9.52e-2)" "unprognostic (3.01e-1)" "potential prognostic unfavorable (8.02e-5)" "unprognostic (1.81e-2)" "unprognostic (8.69e-3)" "unprognostic (2.84e-1)" "unprognostic (6.33e-3)" "unprognostic (2.81e-1)" "unprognostic (1.61e-1)" "unprognostic (2.06e-1)" "unprognostic (1.53e-1)" KANSL3 "FLJ10081, KIAA1310, NSL3, Rcd1" ENSG00000114982 "KAT8 regulatory NSL complex subunit 3" Q9P2N6 2 96593170-96642787 "Essential proteins, Metabolic proteins, Predicted intracellular proteins" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Myonuclei: 182.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035017, HPA035018" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 14 Nucleoplasm Vesicles "HPA035017: , HPA035018: " "unprognostic (1.36e-1)" "unprognostic (7.38e-3)" "unprognostic (7.29e-2)" "unprognostic (8.64e-2)" "unprognostic (1.33e-2)" "unprognostic (3.25e-1)" "unprognostic (6.25e-2)" "unprognostic (1.29e-3)" "unprognostic (3.06e-3)" "potential prognostic favorable (2.32e-6)" "unprognostic (1.38e-2)" "unprognostic (1.22e-1)" "unprognostic (2.57e-1)" "unprognostic (4.63e-3)" "unprognostic (1.28e-1)" "unprognostic (1.00e-1)" "potential prognostic favorable (8.99e-4)" "unprognostic (7.73e-2)" "unprognostic (1.94e-1)" "unprognostic (9.25e-2)" "potential prognostic unfavorable (3.94e-4)" "unprognostic (7.41e-2)" "unprognostic (3.08e-1)" "unprognostic (3.34e-1)" "unprognostic (2.58e-1)" "unprognostic (3.03e-2)" "unprognostic (1.53e-1)" "unprognostic (6.64e-3)" "unprognostic (1.06e-2)" KANTR "LINC01155, Spasm" ENSG00000232593 "KANTR integral membrane protein" X 53094142-53170914 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 7 "brain: 4.7" "Cell type enhanced" "Detected in many" "Somatotrophs: 243.2" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" "unprognostic (8.76e-3)" "unprognostic (3.47e-3)" KARS1 "DFNB89, KARS, KARS2" ENSG00000065427 "Lysyl-tRNA synthetase 1" Q15046 16 75627474-75648643 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase, Transferase" "Charcot-Marie-Tooth disease, Deafness, Disease variant, Intellectual disability, Neurodegeneration, Neuropathy, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 269.0;Late primary spermatocytes: 281.3;Late spermatids: 394.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041345, HPA041550" Enhanced Supported "Plasma membrane,Cytosol" "Intracellular and membrane" Enzyme NA NA 74000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 46 Cytosol "Plasma membrane" "HPA041345: , HPA041550: " "unprognostic (1.23e-3)" "unprognostic (5.25e-2)" "unprognostic (9.31e-2)" "unprognostic (1.63e-1)" "unprognostic (1.99e-1)" "unprognostic (4.85e-2)" "unprognostic (2.25e-2)" "potential prognostic unfavorable (1.85e-5)" "unprognostic (1.54e-2)" "potential prognostic favorable (5.75e-4)" "unprognostic (9.69e-2)" "unprognostic (1.48e-1)" "unprognostic (8.27e-3)" "potential prognostic unfavorable (6.35e-5)" "unprognostic (5.33e-3)" "unprognostic (1.74e-1)" "unprognostic (2.69e-1)" "unprognostic (2.02e-1)" "unprognostic (2.24e-2)" "unprognostic (3.75e-3)" "unprognostic (1.43e-1)" "unprognostic (3.36e-2)" "unprognostic (5.11e-2)" "unprognostic (3.80e-1)" "unprognostic (1.67e-1)" "unprognostic (1.05e-1)" "unprognostic (9.64e-2)" "unprognostic (2.63e-1)" "unprognostic (4.42e-2)" KASH5 "CCDC155, FLJ32658" ENSG00000161609 "KASH domain containing 5" Q8N6L0 19 49388219-49417990 "Predicted intracellular proteins, Predicted membrane proteins" Meiosis "Disease variant, Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "testis: 52.2" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 16.6;Differentiating spermatogonia: 30.9;Early primary spermatocytes: 153.5;Early spermatids: 83.9;Late primary spermatocytes: 80.4;Late spermatids: 31.3;Retinal bipolar cells: 57.1;Rod photoreceptor cells: 15.1" "Cell type enriched" "Detected in single" 13 "upper rhombic lip: 9.8" "Cancer enhanced" "Detected in single" "Testicular Germ Cell Tumor (TCGA): 1.7" "Region enriched" "Detected in single" 10 "cerebellum: 8.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Bone cancer: 5.2" "Testis - Early spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA019937, HPA019940" Enhanced NA NA "Cluster 67: Testis - Mixed function" "Cluster 35: Non-specific - DNA binding" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 3: Early primary spermatocytes - Early meiosis" 98 "HPA019937: , HPA019940: " "unprognostic (2.62e-1)" KAT14 "ATAC2, CRP2BP, CSRP2BP, dJ717M23.1, PRO1194" ENSG00000149474 "Lysine acetyltransferase 14" Q9H8E8 20 18137228-18188387 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 68.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068443 Approved NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 34: Testis cancer - Unknown function" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 28 "HPA068443: " "unprognostic (8.74e-2)" "unprognostic (8.23e-3)" "unprognostic (2.72e-3)" "unprognostic (4.77e-2)" "unprognostic (2.05e-1)" "unprognostic (1.04e-1)" "unprognostic (2.24e-1)" "unprognostic (4.26e-2)" "unprognostic (5.48e-2)" "potential prognostic favorable (2.33e-6)" "unprognostic (2.02e-3)" "unprognostic (1.93e-1)" "unprognostic (1.42e-2)" "unprognostic (1.30e-1)" "unprognostic (2.47e-1)" "unprognostic (1.46e-1)" "unprognostic (6.65e-2)" "unprognostic (2.11e-1)" "unprognostic (1.61e-1)" "unprognostic (9.41e-3)" "unprognostic (5.88e-3)" "unprognostic (1.73e-1)" "unprognostic (5.36e-2)" "unprognostic (3.11e-2)" "unprognostic (1.07e-1)" "unprognostic (4.16e-1)" "unprognostic (1.85e-1)" "unprognostic (1.10e-1)" "unprognostic (1.60e-1)" KAT2A "GCN5, GCN5L2, PCAF-b" ENSG00000108773 "Lysine acetyltransferase 2A" Q92830 17 42113111-42121367 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 99.7;Astrocytes: 96.6;Sertoli cells: 115.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - T-cells, Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048958 Uncertain NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 64: Non-specific - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 94: Gonadal somatic cells - Mixed function" 83 "HPA048958: " "unprognostic (1.52e-1)" "unprognostic (7.59e-3)" "unprognostic (2.89e-2)" "unprognostic (3.43e-2)" "unprognostic (8.53e-3)" "unprognostic (2.20e-2)" "unprognostic (1.99e-1)" "unprognostic (1.13e-2)" "unprognostic (2.90e-2)" "potential prognostic unfavorable (7.63e-5)" "unprognostic (1.36e-2)" "unprognostic (2.52e-1)" "unprognostic (3.08e-3)" "potential prognostic unfavorable (4.33e-4)" "unprognostic (2.19e-1)" "unprognostic (6.10e-3)" "unprognostic (2.45e-3)" "unprognostic (1.72e-1)" "unprognostic (2.69e-1)" "unprognostic (7.91e-2)" "unprognostic (1.67e-1)" "unprognostic (9.45e-2)" "unprognostic (1.17e-2)" "unprognostic (1.29e-2)" "potential prognostic favorable (1.27e-4)" "unprognostic (8.96e-2)" "unprognostic (2.86e-2)" "unprognostic (4.71e-3)" "unprognostic (7.31e-2)" "unprognostic (4.18e-2)" "unprognostic (2.88e-1)" KAT2B "GCN5, GCN5L, P/CAF, PCAF" ENSG00000114166 "Lysine acetyltransferase 2B" Q92831 3 20040446-20154404 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Activator, Acyltransferase, Transferase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bergmann glia: 451.1;Oligodendrocyte progenitor cells: 760.0;Oligodendrocytes: 331.8;Pituicytes/FSCs: 663.0" "Cell type enhanced" "Detected in all" "oligodendrocyte precursor cell: 887.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "skin cancer: 35.4" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002470, CAB004526, HPA055839, HPA073897" Supported Enhanced Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 52: Non-specific - Cellular respiration" "Cluster 19: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 144 Nucleoplasm Cytosol "CAB004526: , HPA002470: , HPA055839: , HPA073897: " "unprognostic (4.17e-2)" "unprognostic (2.80e-2)" "unprognostic (9.93e-3)" "unprognostic (1.37e-1)" "unprognostic (2.77e-1)" "unprognostic (1.52e-1)" "unprognostic (2.91e-2)" "unprognostic (8.25e-2)" "unprognostic (1.21e-2)" "unprognostic (2.67e-2)" "potential prognostic favorable (8.72e-7)" "unprognostic (3.88e-2)" "unprognostic (1.07e-1)" "unprognostic (3.61e-1)" "potential prognostic favorable (1.84e-4)" "potential prognostic favorable (8.66e-4)" "unprognostic (2.63e-1)" "unprognostic (8.12e-2)" "unprognostic (7.31e-2)" "unprognostic (1.70e-1)" "unprognostic (4.25e-1)" "unprognostic (2.01e-2)" "unprognostic (9.52e-2)" "unprognostic (1.22e-1)" "unprognostic (1.55e-1)" "unprognostic (2.47e-1)" "unprognostic (7.58e-2)" "unprognostic (3.61e-2)" "unprognostic (1.92e-1)" "unprognostic (9.87e-2)" "unprognostic (3.20e-1)" KAT5 "cPLA2, ESA1, HTATIP, HTATIP1, PLIP, TIP60, ZC2HC5" ENSG00000172977 "Lysine acetyltransferase 5" Q92993 11 65711996-65719604 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "DNA damage, DNA repair, Growth regulation, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation" "Activator, Acyltransferase, Chromatin regulator, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 152.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016953, HPA074328" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 288 Nucleoplasm "Vesicles, Cytosol" "HPA016953: , HPA074328: " "unprognostic (3.47e-1)" "unprognostic (2.35e-1)" "unprognostic (1.45e-2)" "unprognostic (7.01e-2)" "unprognostic (1.10e-1)" "unprognostic (4.54e-1)" "unprognostic (1.34e-1)" "unprognostic (1.99e-1)" "unprognostic (1.06e-1)" "unprognostic (3.34e-1)" "validated prognostic favorable (4.81e-10)" "validated prognostic favorable (7.57e-5)" "potential prognostic favorable (2.19e-5)" "unprognostic (6.92e-3)" "unprognostic (3.79e-1)" "unprognostic (4.68e-3)" "unprognostic (7.04e-3)" "unprognostic (4.27e-1)" "unprognostic (2.18e-1)" "unprognostic (2.72e-1)" "unprognostic (3.65e-1)" "unprognostic (2.86e-1)" "unprognostic (1.01e-1)" "unprognostic (2.38e-1)" "unprognostic (1.03e-1)" "unprognostic (5.61e-2)" "unprognostic (3.21e-1)" "unprognostic (2.02e-1)" "unprognostic (1.32e-1)" "unprognostic (1.07e-1)" "unprognostic (1.19e-1)" KAT6A "MOZ, MYST3, RUNXBP2, ZC2HC6A, ZNF220" ENSG00000083168 "Lysine acetyltransferase 6A" Q92794 8 41929479-42051994 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Acyltransferase, Chromatin regulator, Repressor, Transferase" "Cancer-related genes, Intellectual disability, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 1366.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Stomach - Endothelial cells" "Low region specificity" "Detected in all" "CAB017023, HPA063266, HPA065052" Supported Supported "Nucleoli,Nuclear speckles,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" 44 "Nuclear speckles" "Nucleoli, Cytosol" "CAB017023: , HPA063266: , HPA065052: " "unprognostic (8.34e-3)" "unprognostic (1.05e-2)" "unprognostic (8.53e-2)" "unprognostic (1.91e-1)" "unprognostic (1.55e-2)" "unprognostic (3.49e-1)" "unprognostic (2.07e-2)" "unprognostic (9.19e-3)" "unprognostic (8.84e-3)" "validated prognostic favorable (1.12e-6)" "validated prognostic favorable (1.71e-4)" "unprognostic (1.80e-1)" "unprognostic (2.63e-1)" "unprognostic (1.07e-1)" "unprognostic (1.44e-3)" "unprognostic (2.12e-1)" "unprognostic (8.20e-3)" "unprognostic (3.30e-2)" "potential prognostic unfavorable (1.49e-4)" "unprognostic (1.26e-1)" "unprognostic (1.56e-3)" "unprognostic (1.02e-1)" "unprognostic (3.79e-2)" "unprognostic (2.05e-2)" "unprognostic (2.23e-1)" "unprognostic (3.88e-1)" "unprognostic (2.77e-1)" "unprognostic (1.95e-2)" "unprognostic (2.90e-1)" KAT6B "Morf, MOZ2, MYST4, qkf, querkopf, ZC2HC6B" ENSG00000156650 "Lysine acetyltransferase 6B" Q8WYB5 10 74824927-75032624 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Acyltransferase, Chromatin regulator, Repressor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 191.2;Bergmann glia: 187.5;Brain excitatory neurons: 199.0;Brain inhibitory neurons: 197.9;Choroid plexus epithelial cells: 237.3;Distal convoluted tubule cells: 244.1;Ependymal cells: 141.6;Loop of henle epithelial cells: 164.0;Microglia: 133.9;Oligodendrocyte progenitor cells: 178.8;Oligodendrocytes: 168.5;Other brain neurons: 122.6;Papillary tip epithelial cells: 149.4;Podocytes: 169.8;Proximal tubule cells: 166.9;Renal collecting duct intercalated cells: 198.7;Renal collecting duct principal cells: 171.2;Renal connecting tubule cells: 224.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006104 Supported Approved "Nucleoplasm,Nucleoli,Nuclear bodies,Mitotic chromosome" Yes NA "Cluster 24: Non-specific - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 102: Non-specific - Mixed function" 5 Nucleoplasm "Nucleoli, Nuclear bodies, Mitotic chromosome" "HPA006104: " "potential prognostic favorable (6.94e-4)" "unprognostic (6.70e-2)" "unprognostic (8.56e-2)" "unprognostic (1.01e-1)" "unprognostic (2.65e-1)" "unprognostic (1.04e-1)" "potential prognostic favorable (4.79e-5)" "unprognostic (7.51e-2)" "unprognostic (8.48e-3)" "potential prognostic favorable (3.37e-6)" "unprognostic (1.03e-3)" "unprognostic (1.18e-1)" "unprognostic (1.10e-1)" "unprognostic (3.40e-1)" "unprognostic (1.23e-1)" "unprognostic (1.67e-1)" "unprognostic (1.49e-2)" "unprognostic (2.50e-2)" "unprognostic (2.41e-2)" "unprognostic (1.73e-1)" "unprognostic (2.27e-2)" "unprognostic (1.25e-1)" "unprognostic (1.97e-1)" "unprognostic (1.72e-2)" "unprognostic (3.40e-1)" "unprognostic (8.36e-2)" "unprognostic (2.58e-1)" "unprognostic (4.21e-2)" "unprognostic (4.69e-1)" KAT7 "HBO1, HBOA, MYST2, ZC2HC7" ENSG00000136504 "Lysine acetyltransferase 7" O95251 17 49788624-49835026 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins, Transcription factors" "DNA damage, DNA repair, DNA replication, Transcription, Transcription regulation" "Acyltransferase, Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Testis - Early spermatids, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044470, HPA071116" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 61 Nucleoplasm Cytosol "HPA044470: , HPA071116: " "unprognostic (6.15e-3)" "unprognostic (1.48e-1)" "unprognostic (9.98e-2)" "unprognostic (1.05e-2)" "unprognostic (1.90e-2)" "unprognostic (1.11e-1)" "unprognostic (2.11e-3)" "unprognostic (2.21e-1)" "unprognostic (3.51e-3)" "validated prognostic favorable (1.36e-5)" "validated prognostic favorable (4.01e-5)" "unprognostic (3.49e-2)" "unprognostic (1.22e-3)" "unprognostic (7.42e-2)" "unprognostic (2.58e-2)" "unprognostic (1.30e-1)" "unprognostic (5.05e-3)" "unprognostic (6.76e-2)" "unprognostic (1.08e-1)" "unprognostic (9.16e-2)" "unprognostic (8.82e-3)" "unprognostic (1.13e-1)" "unprognostic (2.73e-1)" "unprognostic (1.83e-2)" "unprognostic (1.82e-1)" "unprognostic (2.01e-1)" "unprognostic (7.32e-2)" "unprognostic (2.71e-1)" "unprognostic (3.88e-2)" KAT8 "FLJ14040, hMOF, MOF, MYST1, ZC2HC8" ENSG00000103510 "Lysine acetyltransferase 8" Q9H7Z6 16 31114489-31131393 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Acyltransferase, Chromatin regulator, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 166.0;Epididymal principal cells: 208.5;Late spermatids: 230.1;Neutrophils: 135.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 29.9" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066324 Supported Nucleoplasm NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 64: Non-specific - Transcription" "Cluster 2: Neurons - Nucleosome" "Cluster 54: Non-specific - Transcription" "Cluster 24: Neutrophils - Innate immunity signal integration" 34 Nucleoplasm "HPA066324: " "unprognostic (1.32e-1)" "unprognostic (7.78e-2)" "unprognostic (8.35e-2)" "unprognostic (4.48e-2)" "unprognostic (1.32e-1)" "unprognostic (3.83e-2)" "potential prognostic favorable (2.72e-5)" "unprognostic (1.13e-1)" "unprognostic (3.18e-1)" "unprognostic (2.70e-1)" "unprognostic (4.28e-1)" "unprognostic (1.85e-1)" "unprognostic (4.88e-2)" "unprognostic (1.16e-1)" "unprognostic (2.43e-1)" "unprognostic (1.22e-1)" "unprognostic (6.95e-2)" "unprognostic (1.75e-1)" "unprognostic (8.33e-2)" "unprognostic (1.36e-1)" "unprognostic (1.61e-1)" "unprognostic (1.67e-2)" "unprognostic (8.49e-2)" "unprognostic (9.99e-2)" "unprognostic (6.22e-2)" "unprognostic (1.72e-1)" "unprognostic (1.43e-1)" "unprognostic (3.82e-1)" "unprognostic (8.19e-3)" KATNA1 ENSG00000186625 "Katanin catalytic subunit A1" O75449 6 149594873-149648972 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 462.8;Late primary spermatocytes: 275.1;Late spermatids: 278.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036207 Approved Supported "Nucleoplasm,Centriolar satellite" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 39: Testis - Nuclear processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 28: Non-specific - Nuclear processes" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 18 "Centriolar satellite" Nucleoplasm "HPA036207: " "unprognostic (7.00e-2)" "unprognostic (5.03e-2)" "unprognostic (3.86e-2)" "unprognostic (9.67e-2)" "unprognostic (1.31e-1)" "unprognostic (1.59e-1)" "unprognostic (5.75e-2)" "unprognostic (1.67e-2)" "unprognostic (6.54e-2)" "unprognostic (3.81e-2)" "potential prognostic favorable (1.93e-6)" "unprognostic (5.49e-2)" "unprognostic (1.35e-1)" "potential prognostic unfavorable (8.88e-8)" "unprognostic (1.83e-3)" "unprognostic (7.60e-2)" "unprognostic (2.38e-1)" "unprognostic (1.59e-2)" "unprognostic (3.92e-2)" "unprognostic (7.48e-3)" "unprognostic (6.07e-2)" "unprognostic (1.38e-1)" "unprognostic (1.49e-2)" "unprognostic (2.92e-1)" "unprognostic (5.78e-3)" "unprognostic (1.51e-2)" "unprognostic (2.01e-1)" "unprognostic (3.61e-1)" "unprognostic (8.66e-2)" "unprognostic (2.16e-2)" "unprognostic (2.51e-1)" KATNAL1 MGC2599 ENSG00000102781 "Katanin catalytic subunit A1 like 1" Q9BW62 13 30202630-30307551 "Enzymes, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 220.3;Ependymal cells: 152.5;Late primary spermatocytes: 155.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039759 Supported "Mitotic spindle,Centrosome,Mitochondria,Cytosol" Yes NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 89: Adipocytes - Lipid metabolism" 21 "Centrosome, Cytosol" "Mitotic spindle, Mitochondria" "HPA039759: " "unprognostic (1.61e-1)" "unprognostic (2.65e-1)" "unprognostic (2.73e-1)" "unprognostic (3.43e-3)" "unprognostic (9.14e-2)" "potential prognostic unfavorable (2.66e-4)" "unprognostic (1.43e-1)" "unprognostic (1.69e-1)" "unprognostic (5.75e-2)" "unprognostic (3.19e-3)" "potential prognostic favorable (1.23e-6)" "unprognostic (6.86e-3)" "unprognostic (3.00e-1)" "unprognostic (6.90e-3)" "unprognostic (1.46e-1)" "unprognostic (1.55e-1)" "unprognostic (1.55e-2)" "potential prognostic unfavorable (7.64e-4)" "unprognostic (3.45e-3)" "potential prognostic unfavorable (4.50e-4)" "unprognostic (4.00e-2)" "unprognostic (1.39e-1)" "unprognostic (1.15e-2)" "unprognostic (1.04e-1)" "unprognostic (3.22e-1)" "unprognostic (2.51e-3)" "unprognostic (1.33e-1)" "unprognostic (2.49e-1)" "unprognostic (5.01e-2)" "unprognostic (1.70e-1)" "unprognostic (1.42e-1)" KATNAL2 "DKFZP667C165, MGC33211" ENSG00000167216 "Katanin catalytic subunit A1 like 2" Q8IYT4 18 46917492-47103478 "Enzymes, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 11.7;testis: 12.2" "Cell type enhanced" "Detected in many" "Astrocytes: 129.0;Choroid plexus epithelial cells: 298.5;Distal convoluted tubule cells: 114.0;Ependymal cells: 254.7;Late primary spermatocytes: 163.7;Loop of henle epithelial cells: 114.8;Renal connecting tubule cells: 133.4;Respiratory ciliated cells: 126.7" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 271.6;ependymal cell: 257.8" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 27.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040712, HPA042029" Approved Supported "Nucleoplasm,Intermediate filaments" No No "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 34: Ciliated cells - Cilia assembly & function" 3 "Intermediate filaments" Nucleoplasm "HPA040712: , HPA042029: " "unprognostic (1.27e-1)" "unprognostic (1.53e-1)" "unprognostic (2.80e-2)" "unprognostic (1.26e-1)" "unprognostic (4.26e-2)" "unprognostic (2.25e-1)" "unprognostic (4.05e-2)" "potential prognostic unfavorable (2.95e-4)" "unprognostic (9.82e-3)" "unprognostic (6.02e-2)" "unprognostic (2.56e-1)" "potential prognostic favorable (4.45e-4)" "potential prognostic favorable (9.95e-8)" "unprognostic (5.52e-3)" "potential prognostic unfavorable (7.11e-4)" "unprognostic (2.72e-2)" "unprognostic (1.76e-3)" "unprognostic (6.64e-2)" "unprognostic (2.81e-2)" "unprognostic (1.49e-1)" "unprognostic (1.61e-2)" "unprognostic (1.48e-3)" "unprognostic (3.26e-1)" "unprognostic (3.14e-1)" "unprognostic (1.40e-2)" "unprognostic (1.26e-3)" "unprognostic (7.32e-3)" "unprognostic (3.65e-1)" "unprognostic (1.54e-2)" "unprognostic (4.90e-3)" "unprognostic (3.49e-2)" KATNB1 ENSG00000140854 "Katanin regulatory subunit B1" Q9BVA0 16 57735739-57757244 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Disease variant, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 105.9;Fallopian tube ciliated cells: 47.4;Late primary spermatocytes: 135.2;Respiratory ciliated cells: 54.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041165, HPA041839" Enhanced Supported "Plasma membrane,Microtubules,Cytosol" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" 25 Cytosol "Plasma membrane, Microtubules" "HPA041165: , HPA041839: " "unprognostic (3.99e-2)" "unprognostic (4.75e-2)" "unprognostic (3.63e-1)" "unprognostic (2.16e-1)" "unprognostic (1.19e-1)" "unprognostic (1.07e-1)" "unprognostic (2.15e-1)" "potential prognostic favorable (9.88e-5)" "unprognostic (1.26e-1)" "unprognostic (2.88e-1)" "unprognostic (8.64e-2)" "unprognostic (2.77e-3)" "unprognostic (5.00e-3)" "potential prognostic unfavorable (1.06e-5)" "unprognostic (2.66e-1)" "unprognostic (3.95e-2)" "unprognostic (2.28e-1)" "unprognostic (1.89e-2)" "unprognostic (2.18e-1)" "unprognostic (1.80e-1)" "unprognostic (2.81e-2)" "unprognostic (2.74e-2)" "unprognostic (2.29e-1)" "unprognostic (6.36e-3)" "unprognostic (1.24e-2)" "unprognostic (3.82e-1)" "unprognostic (1.17e-1)" "unprognostic (1.89e-1)" "unprognostic (2.99e-1)" "unprognostic (6.91e-2)" "unprognostic (3.03e-2)" KATNBL1 "C15orf29, FLJ22557" ENSG00000134152 "Katanin regulatory subunit B1 like 1" Q9H079 15 34140674-34210096 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1325.5;Neutrophils: 1075.4;Syncytiotrophoblasts: 424.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 127.9" "Lineage enriched" "Detected in all" 4 "granulocytes: 127.9" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062573 Approved Supported "Nucleoplasm,Midbody,Cleavage furrow,Mitotic spindle" Yes No "Cluster 35: Neutrophils - Protein binding" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 31: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 39 "Midbody, Mitotic spindle" "Nucleoplasm, Cleavage furrow" "HPA062573: " "unprognostic (3.20e-1)" "unprognostic (1.10e-1)" "unprognostic (7.85e-2)" "unprognostic (7.31e-2)" "potential prognostic favorable (6.92e-4)" "unprognostic (2.67e-2)" "unprognostic (2.14e-3)" "unprognostic (2.00e-2)" "unprognostic (1.81e-3)" "unprognostic (4.72e-2)" "unprognostic (2.61e-1)" "unprognostic (3.69e-1)" "unprognostic (9.64e-2)" "potential prognostic unfavorable (5.53e-4)" "unprognostic (1.59e-1)" "unprognostic (1.91e-1)" "unprognostic (9.58e-3)" "unprognostic (1.03e-1)" "unprognostic (9.30e-3)" "unprognostic (1.59e-2)" "potential prognostic unfavorable (3.81e-5)" "unprognostic (7.37e-2)" "unprognostic (8.11e-3)" "unprognostic (1.11e-1)" "unprognostic (3.65e-3)" "unprognostic (7.10e-2)" "unprognostic (3.28e-2)" "unprognostic (2.23e-2)" "unprognostic (1.95e-1)" KATNIP "JBTS26, KIAA0556" ENSG00000047578 "Katanin interacting protein" O60303 16 27550133-27780344 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Joubert syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 260.1;Cone photoreceptor cells: 225.6;Endometrial ciliated cells: 224.7;Fallopian tube ciliated cells: 217.5;Respiratory ciliated cells: 336.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 14.3;eosinophil: 3.6;neutrophil: 10.0;NK-cell: 5.0" "Group enriched" "Detected in all" 5 "granulocytes: 14.3;NK-cells: 5.0" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035089, HPA035090" Enhanced Approved "Nucleoplasm,Primary cilium,Centriolar satellite,Basal body" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 1: Neuronal - Visual perception" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 8 "Nucleoplasm, Basal body" "Primary cilium, Centriolar satellite" "HPA035089: , HPA035090: " "unprognostic (9.64e-2)" "unprognostic (2.34e-1)" "unprognostic (2.17e-3)" "unprognostic (1.19e-1)" "unprognostic (2.97e-1)" "unprognostic (1.15e-1)" "unprognostic (1.44e-1)" "unprognostic (8.25e-3)" "potential prognostic unfavorable (5.69e-4)" "unprognostic (1.19e-2)" "unprognostic (2.83e-1)" "unprognostic (1.14e-2)" "unprognostic (6.34e-3)" "unprognostic (4.23e-2)" "unprognostic (7.67e-3)" "unprognostic (1.35e-1)" "unprognostic (1.54e-1)" "unprognostic (4.63e-2)" "unprognostic (3.56e-1)" "unprognostic (1.11e-1)" "unprognostic (6.79e-3)" "unprognostic (2.02e-1)" "unprognostic (1.83e-2)" "unprognostic (1.06e-2)" "unprognostic (4.19e-2)" "unprognostic (2.49e-1)" "unprognostic (2.35e-1)" "unprognostic (5.52e-3)" "unprognostic (9.39e-3)" KAZALD1 "FKSG28, FKSG40" ENSG00000107821 "Kazal type serine peptidase inhibitor domain 1" Q96I82 10 101061989-101068131 "Predicted secreted proteins" "Differentiation, Osteogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 14.0" "Cell type enhanced" "Detected in many" "Colonocytes: 21.3;Enterocytes: 74.9;Foveolar cells: 54.9;Gastric chief cells: 25.1;Goblet cells: 69.9;Mucous neck cells: 23.4" "Cell type enhanced" "Detected in some" "endothelial cell: 3.9;vascular associated smooth muscle cell: 2.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 28.7" "Adipose subcutaneous - Adipose progenitor cells, Kidney - Fibroblasts, Minor Salivary Gland - Minor salivary glandular cells, Skin - Fibroblasts_1, Spleen - Fibroblasts_1, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011800 Uncertain "Secreted to extracellular matrix" "Developmental protein" NA NA 45000 "Cluster 5: Spleen - Immune response" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 70: Intestinal goblet cells - Mucin production" 1 "HPA011800: " "unprognostic (1.87e-2)" "unprognostic (2.98e-1)" "unprognostic (2.20e-1)" "unprognostic (4.54e-3)" "unprognostic (4.03e-3)" "unprognostic (2.88e-1)" "unprognostic (7.70e-2)" "unprognostic (3.60e-1)" "unprognostic (2.77e-1)" "unprognostic (2.03e-2)" "unprognostic (9.33e-2)" "unprognostic (3.02e-1)" "unprognostic (1.68e-1)" "unprognostic (6.38e-2)" "unprognostic (7.16e-2)" "potential prognostic unfavorable (8.24e-4)" "unprognostic (9.19e-2)" "unprognostic (4.54e-2)" "unprognostic (1.24e-1)" "unprognostic (1.46e-1)" "unprognostic (1.38e-3)" "unprognostic (1.02e-1)" "unprognostic (3.31e-2)" "unprognostic (1.05e-1)" "unprognostic (4.49e-2)" KAZN "C1orf196, FLJ43806, KAZRIN, KIAA1026" ENSG00000189337 "Kazrin, periplakin interacting protein" Q674X7 1 13892792-15118043 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 71.8;lymphoid tissue: 88.0" "Cell type enhanced" "Detected in all" "Brain inhibitory neurons: 1871.0;Choroid plexus epithelial cells: 2833.8;Ependymal cells: 1637.5;Loop of henle epithelial cells: 1595.7;Ocular epithelial cells: 1767.6;Oligodendrocyte progenitor cells: 2346.1;Oligodendrocytes: 1545.0;Renal collecting duct principal cells: 1885.9;Renal connecting tubule cells: 2199.9;Retinal ganglion cells: 2221.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 23 "neutrophil: 3.5" "Lineage enriched" "Detected in single" 23 "granulocytes: 3.5" "Low cancer specificity" "Detected in many" "Liver - Hepatic stellate cells, Minor Salivary Gland - Minor salivary gland basal cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032095, HPA032096" Approved Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 5: Spleen - Immune response" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 9 Nucleoplasm "Nuclear speckles, Cytosol" "HPA032095: , HPA032096: " "unprognostic (2.75e-3)" "unprognostic (2.77e-1)" "unprognostic (1.45e-1)" "unprognostic (4.54e-1)" "unprognostic (3.51e-2)" "unprognostic (8.05e-2)" "unprognostic (4.46e-2)" "unprognostic (9.81e-3)" "unprognostic (2.98e-1)" "potential prognostic favorable (9.48e-6)" "unprognostic (1.47e-2)" "potential prognostic favorable (3.36e-5)" "unprognostic (3.35e-2)" "unprognostic (2.00e-3)" "unprognostic (2.24e-2)" "unprognostic (4.33e-2)" "unprognostic (3.24e-1)" "unprognostic (2.21e-1)" "unprognostic (8.61e-3)" "unprognostic (2.66e-1)" "unprognostic (2.43e-1)" "unprognostic (3.53e-1)" "unprognostic (2.91e-1)" "unprognostic (4.07e-1)" "unprognostic (2.20e-2)" "unprognostic (4.22e-2)" "unprognostic (1.30e-1)" "unprognostic (1.60e-2)" "unprognostic (1.45e-1)" "unprognostic (9.70e-2)" KBTBD11 "KIAA0711, KLHDC7C" ENSG00000176595 "Kelch repeat and BTB domain containing 11" O94819 8 1973677-2006936 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.0" "Cell type enhanced" "Detected in some" "Astrocytes: 31.5;Brain excitatory neurons: 25.7;Brain inhibitory neurons: 17.5;Ependymal cells: 21.2;Loop of henle epithelial cells: 22.8;Oligodendrocyte progenitor cells: 15.6;Oligodendrocytes: 16.2;Other brain neurons: 8.9;Podocytes: 42.1;Proximal tubule cells: 31.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in single" "Stomach Adenocarcinoma (TCGA): 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adrenal gland - Adrenal cortex cells, Prostate - Prostate glandular cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051159 Uncertain Approved "Intermediate filaments" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 51: Neurons - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 1 "Intermediate filaments" "HPA051159: " "unprognostic (3.90e-2)" "unprognostic (6.46e-2)" "unprognostic (1.20e-1)" "unprognostic (9.67e-3)" "potential prognostic favorable (2.81e-4)" "unprognostic (3.46e-1)" "unprognostic (1.88e-1)" "unprognostic (3.73e-1)" KBTBD12 "FLJ46299, KLHDC6" ENSG00000187715 "Kelch repeat and BTB domain containing 12" Q3ZCT8 3 127915232-127987671 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 12.9;skeletal muscle: 55.0;tongue: 24.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 103.9;Choroid plexus epithelial cells: 102.6;Early spermatids: 84.8;Microglia: 291.2;Myonuclei: 396.4;Renal collecting duct intercalated cells: 165.3" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 348.3" "Cancer enhanced" "Detected in some" "Kidney Chromophobe (TCGA): 6.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Testis - Late spermatids" "Not detected" "Not detected" "Region enriched" "Detected in all" 5 "cerebellum: 10.0" NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 17: Choroid plexus - Cilium" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" "unprognostic (1.60e-1)" "unprognostic (2.57e-1)" "unprognostic (3.72e-2)" "unprognostic (3.07e-2)" "unprognostic (9.44e-3)" "unprognostic (2.30e-2)" "unprognostic (1.51e-1)" "unprognostic (4.73e-2)" "unprognostic (5.65e-2)" "unprognostic (1.33e-1)" "unprognostic (1.37e-1)" "unprognostic (4.00e-2)" KBTBD13 "hCG_1645727, NEM6" ENSG00000234438 "Kelch repeat and BTB domain containing 13" C9JR72 15 65076746-65079948 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Disease variant, Nemaline myopathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "skeletal muscle: 28.8" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 5.6;Differentiating spermatogonia: 7.3;Early primary spermatocytes: 1.9;Myonuclei: 13.9;Thymic myoid cells: 2.7;Undifferentiated spermatogonia: 2.1;Vascular smooth muscle cells: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA062737 Uncertain NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 35: RS4;11 - Unknown function" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 1 "HPA062737: " KBTBD2 "BKLHD1, DKFZP566C134" ENSG00000170852 "Kelch repeat and BTB domain containing 2" Q8IY47 7 32868172-32894131 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 220.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021133 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center" NA Yes "Cluster 35: Neutrophils - Protein binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 2 "Nucleoplasm, Nucleoli fibrillar center" "HPA021133: " "unprognostic (1.76e-1)" "unprognostic (1.20e-1)" "unprognostic (6.53e-2)" "unprognostic (1.78e-3)" "unprognostic (7.27e-2)" "unprognostic (4.24e-2)" "unprognostic (1.15e-1)" "unprognostic (4.73e-2)" "unprognostic (4.88e-2)" "unprognostic (1.23e-1)" "potential prognostic favorable (7.55e-4)" "unprognostic (2.21e-3)" "unprognostic (3.79e-2)" "potential prognostic unfavorable (8.60e-5)" "unprognostic (9.12e-3)" "unprognostic (1.58e-2)" "unprognostic (1.04e-1)" "unprognostic (3.32e-2)" "unprognostic (2.06e-1)" "unprognostic (2.33e-1)" "unprognostic (1.21e-1)" "unprognostic (9.37e-3)" "unprognostic (5.25e-3)" "unprognostic (2.41e-1)" "unprognostic (8.53e-2)" "unprognostic (3.73e-3)" "unprognostic (1.90e-1)" "unprognostic (1.62e-3)" "unprognostic (3.09e-1)" "unprognostic (1.56e-1)" "unprognostic (3.86e-1)" KBTBD3 BKLHD3 ENSG00000182359 "Kelch repeat and BTB domain containing 3" Q8NAB2 11 106051098-106077459 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 115.2;Late primary spermatocytes: 90.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047385 Uncertain NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 65: Brain - Transcription" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" "HPA047385: " "unprognostic (7.84e-2)" "unprognostic (4.40e-1)" "unprognostic (8.94e-2)" "unprognostic (3.02e-2)" "unprognostic (3.31e-2)" "unprognostic (3.93e-1)" "unprognostic (1.30e-2)" "unprognostic (2.42e-1)" "unprognostic (1.77e-1)" "unprognostic (2.06e-1)" "validated prognostic favorable (1.65e-9)" "validated prognostic favorable (4.78e-4)" "unprognostic (8.29e-2)" "unprognostic (3.37e-1)" "unprognostic (4.54e-2)" "unprognostic (1.90e-3)" "unprognostic (6.63e-2)" "unprognostic (1.42e-2)" "unprognostic (1.19e-1)" "unprognostic (1.19e-1)" "unprognostic (6.72e-3)" "unprognostic (1.26e-1)" "unprognostic (5.79e-2)" "unprognostic (2.10e-2)" "unprognostic (2.05e-1)" "unprognostic (1.84e-2)" "unprognostic (2.74e-2)" "unprognostic (2.18e-1)" "unprognostic (3.68e-1)" "unprognostic (7.80e-2)" "unprognostic (9.93e-2)" KBTBD4 "BKLHD4, FLJ10450, HSPC252" ENSG00000123444 "Kelch repeat and BTB domain containing 4" Q9NVX7 11 47572197-47578976 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 4.8;Bergmann glia: 7.7;Brain excitatory neurons: 8.3;Brain inhibitory neurons: 8.5;Choroid plexus epithelial cells: 4.6;Ependymal cells: 6.9;Loop of henle epithelial cells: 4.6;Microglia: 4.9;Oligodendrocyte progenitor cells: 4.9;Oligodendrocytes: 5.1;Other brain neurons: 8.9;Papillary tip epithelial cells: 4.0;Renal collecting duct principal cells: 4.6;Retinal ganglion cells: 3.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037792, HPA037793" Uncertain Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 24: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" 20 Nucleoplasm "Vesicles, Cytosol" "HPA037792: , HPA037793: " "unprognostic (6.64e-2)" "unprognostic (4.43e-2)" "unprognostic (2.56e-3)" "unprognostic (1.45e-1)" "unprognostic (7.57e-2)" "unprognostic (2.66e-3)" "unprognostic (3.89e-1)" "unprognostic (1.99e-1)" "unprognostic (1.73e-1)" "unprognostic (4.72e-2)" "validated prognostic favorable (2.93e-8)" "validated prognostic favorable (1.85e-4)" "unprognostic (3.36e-2)" "unprognostic (5.19e-2)" "unprognostic (5.15e-1)" "unprognostic (7.01e-2)" "unprognostic (1.28e-1)" "unprognostic (1.34e-1)" "unprognostic (2.30e-1)" "unprognostic (1.99e-1)" "unprognostic (8.08e-3)" "unprognostic (2.93e-2)" "unprognostic (8.39e-2)" "unprognostic (1.42e-1)" "unprognostic (9.59e-3)" "unprognostic (9.48e-2)" "unprognostic (2.16e-1)" "unprognostic (3.37e-1)" "unprognostic (8.28e-2)" "unprognostic (3.51e-1)" "unprognostic (3.11e-2)" KBTBD6 DKFZp547E1912 ENSG00000165572 "Kelch repeat and BTB domain containing 6" Q86V97 13 41127569-41132802 "Predicted intracellular proteins" "Unfolded protein response" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 31.9;Corticotrophs: 31.9;Neutrophil progenitors: 74.4;Neutrophils: 29.9;Other brain neurons: 32.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA046861, HPA048914" Uncertain NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 65: Brain - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 19: Non-specific - Unknown function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 55 "HPA046861: , HPA048914: " "unprognostic (8.83e-2)" "unprognostic (3.34e-2)" "unprognostic (4.78e-3)" "unprognostic (3.44e-3)" "unprognostic (1.68e-1)" "unprognostic (5.01e-2)" "unprognostic (4.82e-3)" "unprognostic (4.77e-1)" "unprognostic (6.79e-2)" "unprognostic (8.30e-3)" "validated prognostic favorable (5.80e-6)" "validated prognostic favorable (3.66e-4)" "unprognostic (8.81e-2)" "unprognostic (1.80e-2)" "unprognostic (1.13e-2)" "unprognostic (1.03e-1)" "unprognostic (3.02e-3)" "unprognostic (8.44e-3)" "unprognostic (4.24e-2)" "unprognostic (7.97e-2)" "unprognostic (7.35e-3)" "unprognostic (1.37e-2)" "unprognostic (2.26e-1)" "unprognostic (2.33e-1)" "unprognostic (1.78e-1)" "unprognostic (8.92e-2)" "unprognostic (7.99e-2)" "unprognostic (3.01e-1)" "unprognostic (3.33e-1)" "unprognostic (1.85e-1)" "unprognostic (2.84e-2)" KBTBD7 DKFZP434E2318 ENSG00000120696 "Kelch repeat and BTB domain containing 7" Q8WVZ9 13 41189834-41194569 "Predicted intracellular proteins" "Ubl conjugation pathway" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 70.5;Epididymal basal cells: 187.3;Neutrophil progenitors: 153.2;Neutrophils: 133.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "HPA043709, HPA046861, HPA048914" Uncertain NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 19: Non-specific - Unknown function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 96 "HPA043709: , HPA046861: , HPA048914: " "unprognostic (1.26e-2)" "unprognostic (4.44e-2)" "unprognostic (4.99e-2)" "unprognostic (2.33e-2)" "unprognostic (1.50e-1)" "unprognostic (9.27e-3)" "unprognostic (3.82e-2)" "unprognostic (4.14e-1)" "unprognostic (2.47e-1)" "unprognostic (3.94e-1)" "validated prognostic favorable (1.28e-7)" "validated prognostic favorable (9.34e-4)" "unprognostic (6.14e-3)" "unprognostic (1.61e-1)" "unprognostic (1.57e-1)" "unprognostic (6.69e-2)" "unprognostic (2.58e-1)" "unprognostic (1.01e-3)" "unprognostic (5.78e-3)" "unprognostic (1.61e-1)" "unprognostic (1.98e-2)" "unprognostic (1.52e-2)" "unprognostic (4.67e-2)" "unprognostic (2.80e-1)" "unprognostic (5.41e-2)" "potential prognostic unfavorable (5.01e-4)" "unprognostic (4.59e-2)" "unprognostic (2.73e-1)" "unprognostic (8.49e-2)" "unprognostic (3.31e-1)" "unprognostic (8.26e-2)" KBTBD8 "KIAA1842, TA-KRP" ENSG00000163376 "Kelch repeat and BTB domain containing 8" Q8NFY9 3 66998307-67011210 "Predicted intracellular proteins" "Translation regulation, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 13.1;lymphoid tissue: 19.4" "Cell type enhanced" "Detected in many" "B-cells: 34.1;Cardiomyocytes: 26.7;cDC: 28.4;Macrophages: 20.1;monocytes: 26.7;Plasma cells: 20.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Leukemia: 7.8;lymphoma: 26.3;Myeloma: 16.2" "Spleen - B-cells (Spleen), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041285, HPA069190" Approved NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 23: Choroid plexus - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 75: Non-specific - Chaperones and protein folding" 13 "HPA041285: , HPA069190: " "unprognostic (5.17e-2)" "unprognostic (1.06e-2)" "unprognostic (9.82e-2)" "unprognostic (3.13e-1)" "unprognostic (2.45e-2)" "unprognostic (3.39e-2)" "unprognostic (2.42e-1)" "unprognostic (1.01e-3)" "unprognostic (5.01e-2)" "unprognostic (1.64e-1)" "unprognostic (3.47e-2)" "unprognostic (1.15e-2)" "unprognostic (2.16e-1)" "unprognostic (5.38e-2)" "unprognostic (2.13e-1)" KCMF1 "DEBT91, DKFZP434L1021, PCMF, ZZZ1" ENSG00000176407 "Potassium channel modulatory factor 1" Q9P0J7 2 84971093-85059472 "Enzymes, Essential proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 425.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030383, HPA030384" Enhanced Enhanced Nucleoplasm,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 51: Secretory epithelial cells - Mixed function" 36 Cytosol Nucleoplasm "HPA030383: , HPA030384: " "unprognostic (1.96e-2)" "unprognostic (2.27e-1)" "unprognostic (2.15e-1)" "unprognostic (2.44e-2)" "unprognostic (6.85e-2)" "unprognostic (9.00e-2)" "unprognostic (3.06e-1)" "unprognostic (8.87e-2)" "unprognostic (4.83e-2)" "potential prognostic unfavorable (1.80e-4)" "potential prognostic favorable (1.88e-5)" "unprognostic (6.83e-2)" "unprognostic (6.91e-3)" "validated prognostic unfavorable (7.24e-4)" "validated prognostic unfavorable (9.21e-5)" "unprognostic (1.12e-2)" "unprognostic (4.61e-2)" "unprognostic (1.17e-1)" "unprognostic (1.72e-1)" "unprognostic (2.25e-3)" "unprognostic (4.24e-3)" "potential prognostic unfavorable (3.89e-5)" "unprognostic (1.29e-3)" "unprognostic (3.22e-1)" "unprognostic (3.85e-1)" "unprognostic (5.25e-2)" "unprognostic (1.21e-1)" "unprognostic (2.00e-1)" "unprognostic (7.17e-2)" "unprognostic (1.22e-1)" "unprognostic (5.46e-2)" KCNA1 "AEMK, HUK1, Kv1.1, MBK1, RBK1" ENSG00000111262 "Potassium voltage-gated channel subfamily A member 1" Q09470 12 4909905-4918256 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 40 "brain: 53.1" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 1.8;Podocytes: 1.3" "Cell type enhanced" "Detected in some" "upper rhombic lip: 2.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "lung cancer: 2.5" "Adipose subcutaneous - Adipose progenitor cells, Minor Salivary Gland - Fibroblasts, Pituitary gland - Thyrotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074471 Approved NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 18 "HPA074471: " "unprognostic (2.28e-2)" KCNA10 Kv1.8 ENSG00000143105 "Potassium voltage-gated channel subfamily A member 10" Q16322 1 110517217-110519175 "FDA approved drug targets, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 11: Neuronal - Sensory perception" 6 KCNA2 "HK4, Kv1.2" ENSG00000177301 "Potassium voltage-gated channel subfamily A member 2" P16389 1 110519837-110631474 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Autism spectrum disorder, Disease variant, Epilepsy, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 33.6;retina: 8.9" "Cell type enhanced" "Detected in some" "Astrocytes: 55.4;Bergmann glia: 29.4;Brain excitatory neurons: 30.1;Brain inhibitory neurons: 33.4;Early spermatids: 38.1;Late spermatids: 19.7;Müller glia: 25.4;Oligodendrocyte progenitor cells: 43.4;Other brain neurons: 14.5;Plasma cells: 17.5;Retinal amacrine cells: 24.9" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in some" 8 "Glioblastoma Multiforme (TCGA): 3.9;Skin Cutaneous Melanoma (TCGA): 1.1;Testicular Germ Cell Tumor (TCGA): 3.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.3" "Lineage enriched" "Detected in single" 8 "T-cells: 1.3" "Group enriched" "Detected in some" 5 "Bone cancer: 8.0;Myeloma: 3.0" "Colon - Enteric glia cells, Pituitary gland - Lactotropes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB001976 Enhanced NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 13 "CAB001976: " "unprognostic (1.35e-1)" "unprognostic (8.14e-2)" "unprognostic (4.55e-1)" "unprognostic (3.11e-2)" "unprognostic (3.44e-1)" KCNA3 "HLK3, HPCN3, Kv1.3, MK3" ENSG00000177272 "Potassium voltage-gated channel subfamily A member 3" P22001 1 110653560-110674940 "FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 1.9;lung: 2.1;lymphoid tissue: 2.5" "Cell type enhanced" "Detected in some" "Corticotrophs: 29.2;Monocyte progenitors: 47.9;Plasma cells: 125.1;Platelets: 486.4;T-cells: 87.9" "Cell type enhanced" "Detected in some" "leukocyte: 6.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "gdT-cell: 5.6;MAIT T-cell: 5.3;memory CD4 T-cell: 8.5;memory CD8 T-cell: 9.6;naive B-cell: 2.6;naive CD4 T-cell: 5.0;naive CD8 T-cell: 4.6;T-reg: 8.5" "Group enriched" "Detected in many" 6 "B-cells: 2.6;T-cells: 9.6" "Cancer enriched" "Detected in some" 5 "Myeloma: 5.6" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Colon - T-cells, Minor Salivary Gland - Plasma cells, Prostate - T-cells, Skin - T-cells, Stomach - Plasma cells, Testis - Spermatocytes, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016625 Approved NA NA "Cluster 11: T-cells - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 1: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 47: Platelets - Hemostasis" 102 "HPA016625: " "unprognostic (7.90e-2)" "unprognostic (1.03e-1)" "unprognostic (4.85e-2)" "unprognostic (2.23e-2)" "unprognostic (8.41e-3)" "unprognostic (1.07e-3)" "unprognostic (4.17e-1)" "unprognostic (1.42e-1)" "unprognostic (7.88e-2)" "unprognostic (4.08e-2)" "unprognostic (2.81e-2)" KCNA4 "HK1, HPCN2, KCNA4L, Kv1.4, PCN2" ENSG00000182255 "Potassium voltage-gated channel subfamily A member 4" P22459 11 30009730-30017030 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Cataract, Disease variant, Dystonia, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 5.8;brain: 7.9" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 14.3;Brain inhibitory neurons: 20.8;Cardiomyocytes: 9.6;Corticotrophs: 28.1;Mesothelial cells: 16.1;Müller glia: 6.7;Other brain neurons: 11.1;Podocytes: 16.5;Retinal bipolar cells: 12.5;Retinal horizontal cells: 18.0;Thyrotrophs: 22.1" "Cell type enhanced" "Detected in many" "mammillary body: 57.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB001977, HPA016422" Approved NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 33: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 35: Neurons - Synaptic function & neurogenesis" 13 "CAB001977: , HPA016422: " "unprognostic (1.86e-3)" KCNA5 "HK2, HPCN1, Kv1.5" ENSG00000130037 "Potassium voltage-gated channel subfamily A member 5" P22460 12 5043879-5046788 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Atrial fibrillation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "blood vessel: 42.2;choroid plexus: 57.3;heart muscle: 36.5" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 11.6;Ependymal cells: 10.2;Pancreatic islet cells: 23.2;pDCs: 20.4;Retinal amacrine cells: 30.6;Retinal bipolar cells: 101.9;Vascular smooth muscle cells: 61.3" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 14.0;ependymal cell: 14.6;vascular associated smooth muscle cell: 38.9" "Cancer enhanced" "Detected in some" "Pancreatic Adenocarcinoma (TCGA): 3.1" "Region enriched" "Detected in all" 7 "choroid plexus: 113.8" "Immune cell enriched" "Detected in single" 122 "plasmacytoid DC: 12.2" "Lineage enriched" "Detected in single" 122 "dendritic cells: 12.2" "Cancer enriched" "Detected in single" 6 "Leukemia: 1.8" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Breast - Endothelial cells, Pancreas - Alpha cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021516, CAB022562" Approved NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 14 "CAB022562: , HPA021516: " "unprognostic (2.26e-1)" "unprognostic (1.91e-1)" "unprognostic (1.99e-1)" "unprognostic (3.36e-3)" "unprognostic (2.29e-2)" "unprognostic (2.23e-2)" "unprognostic (2.03e-1)" KCNA6 "HBK2, Kv1.6, PPP1R96" ENSG00000151079 "Potassium voltage-gated channel subfamily A member 6" P17658 12 4809334-4813318 "FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 9.1" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Glioblastoma Multiforme (TCGA): 4.6;Testicular Germ Cell Tumor (TCGA): 3.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Leukemia: 2.3;testis cancer: 7.8" "Adrenal gland - Adrenal medulla cells, Breast - Fibroblasts, Colon - Colon enteroendocrine cells, Minor Salivary Gland - Fibroblasts, Pancreas - Beta cells, Pituitary gland - Corticotropes, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA076475 Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 59: Leukemia - T-cell receptor" 8 "Plasma membrane, Cytosol" Vesicles "HPA076475: " "unprognostic (2.00e-1)" "unprognostic (2.27e-1)" "unprognostic (4.51e-2)" "unprognostic (1.67e-1)" KCNA7 "HAK6, Kv1.7" ENSG00000104848 "Potassium voltage-gated channel subfamily A member 7" Q96RP8 19 49067397-49072699 "FDA approved drug targets, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 49 "skeletal muscle: 74.6;tongue: 19.2" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 2.1;Epicardial cells: 2.3;Myonuclei: 22.0;Oocytes: 4.6;Platelets: 2.8;Thymic myoid cells: 6.8" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pituitary gland - Gonadotropes, Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA075990 Approved "Vesicles,Plasma membrane" NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 6: Non-specific - Immune response" "Cluster 72: Neuronal - Signal transduction" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" "Vesicles, Plasma membrane" "HPA075990: " "unprognostic (1.53e-2)" "potential prognostic favorable (3.83e-4)" KCNAB1 "AKR6A3, hKvb3, hKvBeta3, KCNA1B, Kvb1.3" ENSG00000169282 "Potassium voltage-gated channel subfamily A regulatory beta subunit 1" Q14722 3 156037701-156539138 "Predicted intracellular proteins, Transporters" "Ion transport, Potassium transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 91.5;brain: 61.2" "Cell type enhanced" "Detected in some" "Early spermatids: 45.9;Gonadotrophs: 47.7;Medullary thymic epithelial cells: 28.8;Oligodendrocytes: 25.9;Pericytes: 36.6;Vascular smooth muscle cells: 167.5" "Cell type enhanced" "Detected in many" "oligodendrocyte: 22.9;vascular associated smooth muscle cell: 41.1" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 23.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in some" "Neuroblastoma: 6.1;thyroid cancer: 5.0" "Adipose subcutaneous - Smooth muscle cells, Breast - Endothelial cells, Colon - Colon enteroendocrine cells, Heart muscle - Smooth muscle cells, Kidney - Fibroblasts, Skeletal muscle - Smooth muscle cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036110, HPA044550" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 74: Non-specific - Signal transduction" "Cluster 33: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 105: Non-specific - Mixed function" 2 Vesicles "Nucleoplasm, Plasma membrane" "HPA036110: , HPA044550: " "unprognostic (3.86e-2)" "unprognostic (4.79e-1)" "unprognostic (1.62e-2)" "unprognostic (7.58e-2)" "unprognostic (1.75e-1)" "unprognostic (3.96e-2)" "unprognostic (1.24e-1)" "unprognostic (6.26e-2)" "validated prognostic favorable (1.20e-8)" "validated prognostic favorable (4.39e-5)" "unprognostic (1.50e-2)" "unprognostic (3.82e-2)" "unprognostic (2.37e-2)" "unprognostic (1.35e-3)" "unprognostic (2.12e-1)" "unprognostic (2.43e-1)" "unprognostic (2.60e-2)" "unprognostic (1.53e-1)" "unprognostic (1.55e-2)" "unprognostic (1.68e-1)" "unprognostic (2.76e-2)" "unprognostic (2.31e-1)" "unprognostic (1.20e-2)" "unprognostic (6.55e-2)" "unprognostic (1.07e-1)" "unprognostic (8.77e-2)" "unprognostic (5.98e-2)" KCNAB2 "AKR6A5, HKvbeta2.1, HKvbeta2.2, KCNA2B" ENSG00000069424 "Potassium voltage-gated channel subfamily A regulatory beta subunit 2" Q13303 1 5990927-6101193 "Plasma proteins, Predicted intracellular proteins" "Ion transport, Potassium transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 202.4" "Cell type enhanced" "Detected in many" "cDC: 100.0;Hematopoietic stem cells: 115.0;Hofbauer cells: 102.8;Kupffer cells: 181.4;Macrophages: 107.3;Melanocytes: 201.6;Monocyte progenitors: 151.0;monocytes: 158.9;Neutrophil progenitors: 160.4;Neutrophils: 239.4;NK-cells: 125.6;pDCs: 107.4;Retinal amacrine cells: 129.9;T-cells: 110.1" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 7 "Skin Cutaneous Melanoma (TCGA): 108.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Leukemia: 141.5" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Macrophages, Minor Salivary Gland - Macrophages, Pituitary gland - Corticotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB001975 Enhanced NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 13 "CAB001975: " "unprognostic (1.59e-1)" "unprognostic (2.81e-1)" "unprognostic (4.87e-2)" "unprognostic (1.66e-1)" "unprognostic (3.14e-3)" "unprognostic (2.58e-1)" "unprognostic (2.17e-2)" "unprognostic (1.11e-2)" "unprognostic (2.27e-2)" "unprognostic (2.02e-1)" "unprognostic (2.44e-1)" "unprognostic (2.82e-1)" "unprognostic (1.63e-1)" "unprognostic (1.29e-2)" "unprognostic (9.22e-3)" "unprognostic (1.31e-2)" "unprognostic (1.45e-1)" "unprognostic (6.38e-2)" "unprognostic (1.38e-1)" "potential prognostic unfavorable (3.35e-4)" "unprognostic (1.03e-2)" "unprognostic (2.93e-2)" "unprognostic (4.61e-2)" "unprognostic (3.23e-2)" "unprognostic (4.25e-1)" "unprognostic (6.54e-3)" "unprognostic (4.05e-2)" "unprognostic (1.03e-1)" "unprognostic (4.97e-2)" "unprognostic (2.89e-2)" "unprognostic (3.02e-2)" KCNAB3 "AKR6A9, KCNA3B" ENSG00000170049 "Potassium voltage-gated channel subfamily A regulatory beta subunit 3" O43448 17 7921859-7929856 "Predicted intracellular proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Oxidoreductase, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 34.2;endometrium 1: 14.3" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 20.8;Decidual stromal cells: 28.5;Endometrial stromal cells: 12.5;Müller glia: 10.7;Oligodendrocyte progenitor cells: 12.3;Retinal amacrine cells: 48.6;Retinal bipolar cells: 11.4;Retinal horizontal cells: 52.1" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 56.7;midbrain-derived inhibitory: 66.6" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 5.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 8.0" "Adipose visceral - Mesothelial cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077993 Approved Mitochondria NA NA "Cluster 64: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 4 Mitochondria "HPA077993: " "unprognostic (3.16e-1)" "unprognostic (1.22e-1)" "unprognostic (3.43e-2)" "unprognostic (9.85e-2)" "unprognostic (9.46e-2)" "unprognostic (2.64e-1)" "unprognostic (7.86e-3)" "unprognostic (2.63e-3)" "unprognostic (6.43e-3)" "unprognostic (2.08e-1)" "unprognostic (7.87e-2)" "unprognostic (7.03e-2)" KCNB1 Kv2.1 ENSG00000158445 "Potassium voltage-gated channel subfamily B member 1" Q14721 20 49293394-49484297 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Exocytosis, Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "retina: 106.5" "Group enriched" "Detected in many" 4 "Cone photoreceptor cells: 577.6;Rod photoreceptor cells: 1205.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 2.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 3.5;Rhabdoid: 4.0" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal medulla cells, Breast - Adipocytes (Breast), Pituitary gland - Thyrotropes, Prostate - Smooth muscle cells, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001979, HPA042434" Enhanced NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" 8 "CAB001979: , HPA042434: " "unprognostic (1.80e-1)" "unprognostic (2.86e-1)" "potential prognostic favorable (7.76e-7)" "unprognostic (4.95e-2)" "unprognostic (7.89e-2)" "unprognostic (2.76e-2)" "unprognostic (1.39e-3)" KCNB2 Kv2.2 ENSG00000182674 "Potassium voltage-gated channel subfamily B member 2" Q92953 8 72537225-72938349 "FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.0;lymphoid tissue: 2.2;retina: 4.2" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 338.9;Cone photoreceptor cells: 5059.4;Corticotrophs: 1310.8;Gonadotrophs: 593.3;Neuroendocrine cells: 864.1;Other brain neurons: 383.4;Pancreatic islet cells: 560.3;Pituitary stem cells: 793.2;Retinal amacrine cells: 469.4;Somatotrophs: 481.7;Thyrotrophs: 359.1" "Cell type enhanced" "Detected in all" "miscellaneous: 1482.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 2.8" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Stomach - Gastric enteroendocrine cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" HPA065970 Approved "Nucleoli,Plasma membrane,Midbody" Yes NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 79: Photoreceptor cells - Phototransduction" 2 "Plasma membrane" "Nucleoli, Midbody" "HPA065970: " "unprognostic (3.13e-2)" KCNC1 Kv3.1 ENSG00000129159 "Potassium voltage-gated channel subfamily C member 1" P48547 11 17734774-17856804 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "brain: 98.9" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 118.4;Brain inhibitory neurons: 85.5;Cardiomyocytes: 48.7;Epicardial cells: 81.9;Other brain neurons: 56.3;Retinal amacrine cells: 310.8;Retinal bipolar cells: 69.1;Retinal ganglion cells: 108.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 3.3;neutrophil: 1.3" "Lineage enriched" "Detected in single" 7 "granulocytes: 3.3" "Cancer enhanced" "Detected in some" "Neuroblastoma: 7.7" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pituitary gland - Corticotropes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047634, HPA048249" Enhanced Approved "Nucleoplasm,Nuclear membrane,Vesicles,Cytosol" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 27: Cerebellum - Synaptic function" "Cluster 37: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 2 "Nucleoplasm, Nuclear membrane" "Vesicles, Cytosol" "HPA047634: , HPA048249: " "unprognostic (3.33e-2)" "unprognostic (3.85e-1)" "unprognostic (2.73e-2)" "unprognostic (1.76e-1)" "unprognostic (1.62e-2)" "unprognostic (5.10e-2)" "unprognostic (1.18e-1)" KCNC2 Kv3.2 ENSG00000166006 "Potassium voltage-gated channel subfamily C member 2" Q96PR1 12 75040077-75209839 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 33.8" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 218.1;Brain inhibitory neurons: 448.0;Lactotrophs: 449.1;Other brain neurons: 464.7;Retinal amacrine cells: 518.8;Retinal ganglion cells: 1158.8;Somatotrophs: 368.8;Thyrotrophs: 522.3" "Cell type enhanced" "Detected in all" "LAMP5-LHX6 and Chandelier: 2159.6;MGE interneuron: 1938.6" "Group enriched" "Detected in some" 8 "Breast Invasive Carcinoma (TCGA): 5.6;Prostate Adenocarcinoma (TCGA): 14.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 1.2;Sarcoma: 1.0" "Breast - Breast glandular cells, Colon - Colon enteroendocrine cells, Pituitary gland - Lactotropes, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019664, CAB022571" Uncertain NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 109: Neurons - Neuronal signaling" "CAB022571: , HPA019664: " "unprognostic (3.60e-1)" "unprognostic (1.80e-1)" "unprognostic (1.21e-1)" "unprognostic (1.75e-2)" "unprognostic (1.60e-1)" "unprognostic (1.30e-1)" KCNC3 "Kv3.3, SCA13" ENSG00000131398 "Potassium voltage-gated channel subfamily C member 3" Q14003 19 50311937-50333515 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, FDA approved drug targets, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 56.7;thyroid gland: 39.3" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 57.1;Epididymal efferent duct absorptive cells: 52.4;Fallopian secretory cells: 44.3;Fallopian tube ciliated cells: 37.4;Microglia: 39.9;Proximal tubule cells: 61.5;Renal collecting duct intercalated cells: 50.1;Renal collecting duct principal cells: 55.2;Renal connecting tubule cells: 38.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Macrophages, Lung - Alveolar cells type 2, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018041 Approved NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 55: Lymphoma - Immune response" "Cluster 88: Proximal tubular cells - Transmembrane transport" 11 "HPA018041: " "unprognostic (3.29e-3)" "unprognostic (1.12e-1)" "potential prognostic favorable (1.67e-4)" "unprognostic (2.05e-1)" "unprognostic (3.70e-1)" "unprognostic (6.61e-3)" "unprognostic (1.24e-1)" "unprognostic (1.27e-2)" "unprognostic (3.21e-1)" "unprognostic (1.98e-1)" "unprognostic (1.40e-1)" "unprognostic (1.12e-2)" "unprognostic (2.73e-2)" "unprognostic (8.21e-2)" "unprognostic (5.26e-2)" "unprognostic (1.13e-1)" "unprognostic (3.09e-1)" "unprognostic (2.79e-2)" "unprognostic (6.38e-3)" "unprognostic (3.17e-1)" "unprognostic (1.15e-3)" "unprognostic (3.10e-2)" "potential prognostic unfavorable (3.45e-4)" "unprognostic (8.15e-2)" "unprognostic (1.45e-2)" "unprognostic (6.01e-2)" "unprognostic (1.57e-1)" "unprognostic (3.87e-2)" "unprognostic (7.63e-2)" KCNC4 "C1orf30, HKSHIIIC, Kv3.4" ENSG00000116396 "Potassium voltage-gated channel subfamily C member 4" Q03721 1 110210314-110283100 "Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.7" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 74.5;Distal convoluted tubule cells: 55.2;Endometrial luminal cells: 51.9;Lacrimal acinar cells: 52.5;Renal collecting duct intercalated cells: 92.5;Renal connecting tubule cells: 94.6;Rod photoreceptor cells: 74.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014740 Approved Nucleoli,Cytosol NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 24: Neurons - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 79: Photoreceptor cells - Phototransduction" 1 "Nucleoli, Cytosol" "HPA014740: " "unprognostic (1.04e-1)" "unprognostic (5.29e-1)" "unprognostic (3.46e-2)" "unprognostic (8.94e-2)" "unprognostic (8.41e-3)" "unprognostic (3.71e-1)" "unprognostic (6.06e-2)" "unprognostic (2.26e-1)" "unprognostic (4.69e-2)" "unprognostic (4.54e-1)" "potential prognostic favorable (9.91e-5)" "unprognostic (1.38e-3)" "unprognostic (2.03e-2)" "unprognostic (5.89e-2)" "unprognostic (1.42e-1)" "unprognostic (1.41e-1)" "unprognostic (3.35e-1)" "unprognostic (1.65e-1)" "unprognostic (4.23e-1)" "unprognostic (1.44e-2)" "unprognostic (5.83e-3)" "unprognostic (2.44e-1)" "unprognostic (1.55e-1)" "unprognostic (4.35e-2)" "unprognostic (8.56e-2)" "unprognostic (2.98e-2)" "unprognostic (2.51e-2)" "unprognostic (3.91e-1)" "unprognostic (2.36e-1)" "unprognostic (9.42e-2)" KCND1 Kv4.1 ENSG00000102057 "Potassium voltage-gated channel subfamily D member 1" Q9NSA2 X 48961378-48971844 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.7" "Cell type enhanced" "Detected in some" "Fibroblasts: 2.4;Hepatic stellate cells: 6.5;Neutrophil progenitors: 2.7;Neutrophils: 3.0;pDCs: 2.6;Peritubular myoid cells: 3.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000524, HPA001066" Supported Uncertain Nucleoplasm Yes No "Cluster 64: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 108: Fibroblasts - ECM organization" Nucleoplasm "HPA000524: , HPA001066: " "unprognostic (2.38e-2)" "unprognostic (1.78e-1)" "unprognostic (3.50e-1)" "unprognostic (1.10e-1)" "unprognostic (2.20e-2)" "unprognostic (1.67e-1)" "unprognostic (2.53e-1)" "potential prognostic unfavorable (1.19e-5)" "unprognostic (1.64e-2)" "unprognostic (9.18e-3)" "unprognostic (6.29e-3)" "unprognostic (1.23e-1)" "unprognostic (1.62e-1)" "unprognostic (1.15e-1)" "potential prognostic unfavorable (2.88e-4)" "unprognostic (1.48e-1)" "potential prognostic favorable (3.21e-5)" "unprognostic (8.48e-3)" "unprognostic (1.23e-1)" "unprognostic (2.30e-2)" "unprognostic (1.00e-1)" "unprognostic (4.37e-2)" "unprognostic (6.83e-2)" "unprognostic (3.44e-2)" KCND2 "KIAA1044, Kv4.2, RK5" ENSG00000184408 "Potassium voltage-gated channel subfamily D member 2" Q9NZV8 7 120273175-120750337 "Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Autism, Autism spectrum disorder, Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "brain: 32.3" "Cell type enhanced" "Detected in many" "Astrocytes: 613.8;Bergmann glia: 1841.9;Brain excitatory neurons: 2155.6;Brain inhibitory neurons: 1745.6;Corticotrophs: 1617.2;Fibro-adipogenic progenitors: 814.9;Lactotrophs: 2549.4;Oligodendrocyte progenitor cells: 2968.6;Other brain neurons: 1018.9;Thyrotrophs: 810.0" "Cell type enhanced" "Detected in all" "midbrain-derived inhibitory: 5323.0;upper rhombic lip: 5357.6" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 12.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 2.9" "Pituitary gland - Lactotropes, Skeletal muscle - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029068 Enhanced NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 37: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 11 "HPA029068: " "unprognostic (3.12e-2)" "unprognostic (1.29e-1)" "unprognostic (1.48e-2)" "unprognostic (3.55e-1)" "potential prognostic favorable (2.04e-5)" "unprognostic (1.35e-3)" "unprognostic (1.39e-1)" "unprognostic (7.16e-2)" "unprognostic (1.43e-1)" "unprognostic (1.13e-1)" "unprognostic (1.92e-2)" "unprognostic (1.41e-2)" "unprognostic (5.03e-2)" KCND3 "KSHIVB, Kv4.3, SCA19, SCA22" ENSG00000171385 "Potassium voltage-gated channel subfamily D member 3" Q9UK17 1 111770662-111989668 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Brugada syndrome, Disease variant, FDA approved drug targets, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.5" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 241.2;Brain inhibitory neurons: 150.9;Cardiomyocytes: 239.0;Lactotrophs: 135.6;Myonuclei: 272.5;Oligodendrocyte progenitor cells: 143.5;Retinal bipolar cells: 265.2;Retinal horizontal cells: 144.2;Thyrotrophs: 379.5" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 12.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 1.6" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029452 Approved NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 4 "HPA029452: " "unprognostic (2.39e-3)" "unprognostic (9.43e-3)" "unprognostic (1.18e-1)" "unprognostic (6.72e-2)" "unprognostic (1.88e-1)" "unprognostic (1.83e-1)" "unprognostic (1.51e-1)" "unprognostic (1.34e-3)" "unprognostic (2.94e-1)" "unprognostic (1.68e-1)" "unprognostic (5.41e-3)" "unprognostic (2.58e-3)" "unprognostic (1.82e-1)" "unprognostic (4.59e-3)" "unprognostic (9.59e-3)" "unprognostic (9.40e-3)" "unprognostic (4.55e-2)" "unprognostic (9.48e-2)" "unprognostic (4.74e-2)" "unprognostic (2.23e-2)" "unprognostic (5.09e-2)" "unprognostic (1.23e-2)" "unprognostic (1.50e-1)" "unprognostic (3.62e-1)" KCNE1 "IsK, JLNS2, LQT5, minK" ENSG00000180509 "Potassium voltage-gated channel subfamily E regulatory subunit 1" P15382 21 34446688-34512214 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Deafness, Disease variant, Long QT syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "choroid plexus: 14.9;fallopian tube: 14.4;heart muscle: 10.7;kidney: 3.9" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 192.9;Endometrial ciliated cells: 134.2;Ependymal cells: 94.3;Epididymal efferent duct ciliated cells: 120.0;Monocyte progenitors: 191.5;monocytes: 154.7;Neutrophil progenitors: 173.7;Neutrophils: 726.7;Respiratory ciliated cells: 249.7" "Group enriched" "Detected in many" 8 "choroid plexus epithelial cell: 125.2;ependymal cell: 79.6" "Cancer enhanced" "Detected in single" "Uterine Corpus Endometrial Carcinoma (TCGA): 1.4" "Region enriched" "Detected in all" 8 "choroid plexus: 46.6" "Immune cell enhanced" "Detected in some" "eosinophil: 2.8" "Lineage enhanced" "Detected in single" "granulocytes: 2.8" "Cancer enhanced" "Detected in some" "Adrenocortical cancer: 2.1;Rhabdoid: 4.6" "Adipose subcutaneous - Macrophages, Prostate - Macrophages, Spleen - Neutrophils_2" "Not detected" "Not detected" "Region enhanced" "Detected in many" "spinal cord: 6.8" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 72: Neuronal - Signal transduction" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 4 "unprognostic (1.32e-2)" "unprognostic (8.46e-2)" "unprognostic (5.94e-2)" "unprognostic (1.38e-2)" KCNE2 "LQT6, MiRP1" ENSG00000159197 "Potassium voltage-gated channel subfamily E regulatory subunit 2" Q9Y6J6 21 34364006-34371381 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Atrial fibrillation, Disease variant, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 44 "stomach 1: 299.1" "Group enriched" "Detected in some" 7 "Gastric chief cells: 772.1;Parietal cells: 2376.1" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Stomach Adenocarcinoma (TCGA): 5.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Stomach - Parietal cells" "Region enhanced" "Detected in many" "pons and medulla: 29.0" "Not detected" "Not detected" "HPA029706, HPA051553" Enhanced NA NA "Cluster 60: Stomach - Digestion" "Cluster 1: Neurons - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 97: Non-specific - Cellular respiration" 1 "HPA029706: , HPA051553: " "potential prognostic unfavorable (8.11e-4)" "unprognostic (3.34e-1)" "unprognostic (8.05e-2)" "unprognostic (2.26e-2)" "unprognostic (3.04e-2)" "unprognostic (1.28e-1)" "unprognostic (3.84e-1)" "unprognostic (3.15e-1)" "unprognostic (4.05e-2)" KCNE3 "HOKPP, MiRP2" ENSG00000175538 "Potassium voltage-gated channel subfamily E regulatory subunit 3" Q9Y6H6 11 74454841-74467729 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Transport" "Brugada syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 66.2;stomach 1: 53.0" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 45.6;Enteric stem cells: 45.2;Foveolar cells: 50.1;Gastric progenitor cells: 87.2;Hofbauer cells: 68.3;Kupffer cells: 133.2;Megakaryocytes: 98.9;Monocyte progenitors: 56.9;monocytes: 73.4;Mucous neck cells: 86.4;Neutrophil progenitors: 74.2;Neutrophils: 130.2;Paneth cells: 69.6;Platelets: 66.5;Respiratory secretory cells: 50.6" "Group enriched" "Detected in some" 4 "central nervous system macrophage: 27.9;endothelial cell: 9.8;fibroblast: 18.0;leukocyte: 7.2;pericyte: 20.2;vascular associated smooth muscle cell: 8.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 49 "basophil: 51.7;classical monocyte: 38.6;eosinophil: 23.5;intermediate monocyte: 41.8;myeloid DC: 18.3;neutrophil: 53.4;non-classical monocyte: 36.8" "Group enriched" "Detected in many" 123 "dendritic cells: 18.3;granulocytes: 53.4;monocytes: 41.8" "Cancer enhanced" "Detected in many" "Bone cancer: 68.1;cervical cancer: 61.1" "Adipose subcutaneous - Macrophages, Adrenal gland - Macrophages, Prostate - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA014849 Approved Supported "Plasma membrane" NA NA 10000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 77: Intestine - Digestion" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 32: Non-specific - Cell proliferation" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 72 "Plasma membrane" "HPA014849: " "unprognostic (7.59e-2)" "unprognostic (1.99e-2)" "unprognostic (2.20e-3)" "unprognostic (4.99e-1)" "unprognostic (2.87e-2)" "unprognostic (1.96e-2)" "unprognostic (1.27e-1)" "unprognostic (2.31e-1)" "unprognostic (1.58e-1)" "unprognostic (3.71e-2)" "unprognostic (1.20e-3)" "potential prognostic favorable (3.11e-4)" "unprognostic (2.58e-1)" "unprognostic (1.74e-3)" "unprognostic (1.86e-2)" "unprognostic (1.93e-2)" "unprognostic (3.30e-2)" "unprognostic (5.58e-2)" "unprognostic (2.25e-2)" "unprognostic (1.55e-1)" "unprognostic (1.76e-1)" "unprognostic (3.96e-2)" "potential prognostic favorable (7.95e-4)" "unprognostic (2.22e-2)" "unprognostic (2.26e-1)" "unprognostic (4.59e-3)" "potential prognostic unfavorable (1.73e-4)" "unprognostic (3.25e-2)" "unprognostic (1.11e-1)" "unprognostic (1.18e-1)" "unprognostic (3.22e-1)" KCNE4 MiRP3 ENSG00000152049 "Potassium voltage-gated channel subfamily E regulatory subunit 4" Q8WWG9 2 223052190-223198399 "Predicted membrane proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 39.9" "Cell type enhanced" "Detected in many" "Astrocytes: 50.6;Corticotrophs: 43.4;Fibroblasts: 77.5;Gastric chief cells: 88.5;Hepatic stellate cells: 103.3;Leydig cells: 41.2;Melanocytes: 85.2;Pericytes: 194.4;Smooth muscle cells: 140.6;Vascular smooth muscle cells: 95.9" "Cell type enhanced" "Detected in many" "fibroblast: 270.6;pericyte: 236.0" "Cancer enhanced" "Detected in all" "Breast Invasive Carcinoma (TCGA): 36.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 45.4" "Lung - Fibroblasts_2, Prostate - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA011420 Approved Approved "Nuclear bodies,Microtubules" NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 103: Non-specific - Basic cellular processes" 18 Microtubules "Nuclear bodies" "HPA011420: " "unprognostic (5.23e-3)" "unprognostic (1.13e-1)" "unprognostic (4.22e-1)" "unprognostic (1.71e-3)" "unprognostic (2.00e-3)" "unprognostic (7.67e-3)" "unprognostic (3.11e-2)" "potential prognostic unfavorable (2.92e-6)" "unprognostic (2.30e-1)" "unprognostic (5.67e-3)" "unprognostic (1.89e-3)" "unprognostic (1.10e-2)" "unprognostic (2.64e-3)" "unprognostic (3.10e-2)" "unprognostic (3.12e-1)" "unprognostic (1.01e-1)" "unprognostic (1.91e-1)" "unprognostic (7.91e-3)" "unprognostic (1.43e-2)" "unprognostic (5.14e-2)" "unprognostic (4.25e-3)" "unprognostic (1.79e-1)" "unprognostic (2.73e-1)" "unprognostic (8.67e-2)" "unprognostic (7.06e-2)" "unprognostic (3.34e-3)" "unprognostic (8.76e-2)" "unprognostic (1.02e-2)" "unprognostic (8.68e-2)" "unprognostic (1.07e-2)" "unprognostic (1.83e-2)" KCNE5 KCNE1L ENSG00000176076 "Potassium voltage-gated channel subfamily E regulatory subunit 5" Q9UJ90 X 109623700-109625172 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Alport syndrome, Deafness, Elliptocytosis, Hereditary hemolytic anemia, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 16.6;tongue: 4.5" "Cell type enhanced" "Detected in some" "Astrocytes: 4.7;Bergmann glia: 13.4;Ependymal cells: 2.8;Melanocytes: 4.1;Monocyte progenitors: 23.7;Müller glia: 3.3;Oocytes: 4.6;Retinal pigment epithelial cells: 4.3" "Group enriched" "Detected in some" 6 "astrocyte: 7.8;Bergmann glia: 23.0;ependymal cell: 9.2" "Cancer enriched" "Detected in some" 4 "Glioblastoma Multiforme (TCGA): 14.5" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "myeloid DC: 2.3" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in some" 11 "Leukemia: 11.7" "Adipose subcutaneous - Adipocytes (Subcutaneous)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 4 "unprognostic (3.28e-2)" "unprognostic (2.34e-2)" "unprognostic (1.26e-1)" KCNF1 "IK8, KCNF, kH1, Kv5.1" ENSG00000162975 "Potassium voltage-gated channel modifier subfamily F member 1" Q9H3M0 2 10911934-10914225 "Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 28 "brain: 45.3;choroid plexus: 23.5" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 7.8;Brain inhibitory neurons: 10.7;Choroid plexus epithelial cells: 17.0;Extravillous trophoblasts: 22.9;Fallopian secretory cells: 5.1;Late spermatids: 5.8;Oligodendrocyte progenitor cells: 31.4;Other brain neurons: 7.7;Schwann cells: 4.9;Syncytiotrophoblasts: 10.4" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in many" 7 "Glioblastoma Multiforme (TCGA): 46.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 11.5;lung cancer: 9.0" "Breast - Breast glandular cells (progenitors), Pancreas - Beta cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA014738, HPA062278" Enhanced Approved "Nucleoplasm,Golgi apparatus,Vesicles,Primary cilium transition zone" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 23: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 35: Neurons - Synaptic function & neurogenesis" 9 "Golgi apparatus" "Nucleoplasm, Vesicles, Primary cilium transition zone" "HPA014738: , HPA062278: " "unprognostic (1.30e-1)" "unprognostic (1.26e-1)" "unprognostic (2.13e-1)" "unprognostic (9.72e-2)" "unprognostic (6.57e-2)" "potential prognostic favorable (9.92e-4)" "unprognostic (6.80e-2)" "unprognostic (1.11e-1)" "unprognostic (5.33e-2)" "unprognostic (8.49e-2)" "unprognostic (3.43e-3)" "unprognostic (1.29e-1)" KCNG1 "K13, KCNG, kH2, Kv6.1" ENSG00000026559 "Potassium voltage-gated channel modifier subfamily G member 1" Q9UIX4 20 51003656-51023107 "Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 49.5;endometrium 1: 80.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 73.0;Endometrial luminal cells: 24.3;Ependymal cells: 20.5;Esophageal apical cells: 36.0;Late primary spermatocytes: 25.7;Late spermatids: 34.6;Migrating cytotrophoblasts: 22.5;Sertoli cells: 19.4;Smooth muscle cells: 17.3;Syncytiotrophoblasts: 109.3" "Cell type enhanced" "Detected in many" "amygdala excitatory: 48.3" "Cancer enriched" "Detected in many" 4 "Bladder Urothelial Carcinoma (TCGA): 48.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 18 "naive B-cell: 7.1" "Lineage enriched" "Detected in single" 72 "B-cells: 7.1" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal medulla cells, Minor Salivary Gland - Minor salivary gland basal cells, Testis - Sertoli cells" "Group enriched" "Detected in many" 5 "amygdala: 20.6;basal ganglia: 19.1;cerebral cortex: 14.9;hippocampal formation: 18.1;white matter: 9.1" "Group enriched" "Detected in all" 5 "amygdala: 17.3;basal ganglia: 15.0;cerebral cortex: 29.9;hippocampal formation: 22.6" "HPA039530, HPA040024" Approved Approved Vesicles NA NA "Cluster 34: B-cells - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 14: Neurons - Synaptic function" "Cluster 72: Neuronal - Signal transduction" "Cluster 63: Cytotrophoblasts - Basic cellular functions" Vesicles "HPA039530: , HPA040024: " "unprognostic (1.16e-1)" "unprognostic (2.40e-1)" "unprognostic (1.07e-1)" "unprognostic (1.25e-2)" "unprognostic (1.86e-1)" "unprognostic (8.71e-2)" "unprognostic (1.06e-1)" "unprognostic (8.87e-3)" "potential prognostic unfavorable (7.47e-4)" "unprognostic (2.18e-1)" "unprognostic (8.65e-2)" "unprognostic (1.05e-1)" "unprognostic (4.01e-3)" "unprognostic (2.38e-2)" "unprognostic (2.48e-1)" "unprognostic (1.77e-1)" "potential prognostic unfavorable (1.20e-4)" "unprognostic (1.78e-1)" "unprognostic (2.84e-1)" "unprognostic (6.75e-2)" "unprognostic (5.59e-2)" "unprognostic (3.77e-2)" "unprognostic (1.68e-1)" "unprognostic (1.59e-1)" KCNG2 "KCNF2, Kv6.2" ENSG00000178342 "Potassium voltage-gated channel modifier subfamily G member 2" Q9UJ96 18 79797938-79900184 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 2.5" "Cell type enhanced" "Detected in many" "Epicardial cells: 172.8;monocytes: 57.6;Neutrophils: 119.7;Oocytes: 69.1;pDCs: 121.2;Retinal horizontal cells: 306.5;Thymocytes: 64.4" "Cell type enhanced" "Detected in many" "hippocampal CA4: 41.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 4 "hippocampal formation: 24.5" HPA048628 Enhanced NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 29: Forebrain - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" "HPA048628: " "unprognostic (3.27e-2)" KCNG3 Kv6.3 ENSG00000171126 "Potassium voltage-gated channel modifier subfamily G member 3" Q8TAE7 2 42442017-42493982 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.0" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 33.6;Corticotrophs: 69.7;Endometrial ciliated cells: 80.7;Endometrial glandular cells: 139.2;Endometrial luminal cells: 170.3;Pituicytes/FSCs: 35.6;Renal collecting duct intercalated cells: 56.5;Thyrotrophs: 39.5" "Cell type enhanced" "Detected in many" "hippocampal CA4: 88.1;hippocampal dentate gyrus: 82.0;upper-layer intratelencephalic: 55.3" "Cancer enhanced" "Detected in some" "Prostate Adenocarcinoma (TCGA): 1.6;Testicular Germ Cell Tumor (TCGA): 1.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Rhabdoid: 7.1" "Lung - Alveolar cells type 2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA041625 Approved "Cytoplasmic bodies" NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 51: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 1 "Cytoplasmic bodies" "HPA041625: " "unprognostic (1.29e-1)" "unprognostic (4.22e-3)" "unprognostic (2.33e-1)" "unprognostic (2.36e-1)" KCNG4 Kv6.4 ENSG00000168418 "Potassium voltage-gated channel modifier subfamily G member 4" Q8TDN1 16 84218657-84240012 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "retina: 3.6" "Cell type enriched" "Detected in some" 6 "Retinal bipolar cells: 74.0" "Cell type enriched" "Detected in some" 13 "oligodendrocyte precursor cell: 14.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adrenal gland - Adrenal medulla cells, Minor Salivary Gland - Minor salivary glandular cells" "Group enriched" "Detected in all" 4 "cerebellum: 90.5;pons and medulla: 27.0" "Low region specificity" "Detected in many" HPA063516 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 43: Hindbrain - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 2 "Plasma membrane" Nucleoplasm "HPA063516: " KCNH1 "eag, eag1, h-eag, hEAG, Kv10.1" ENSG00000143473 "Potassium voltage-gated channel subfamily H member 1" O95259 1 210676823-211134165 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Calmodulin-binding, Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "brain: 15.6" "Cell type enriched" "Detected in many" 4 "Respiratory ionocytes: 609.6" "Cell type enhanced" "Detected in all" "hippocampal dentate gyrus: 338.3;upper-layer intratelencephalic: 317.5" "Cancer enhanced" "Detected in some" "Breast Invasive Carcinoma (TCGA): 2.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "Adrenocortical cancer: 20.7" "Skin - Outer root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014551, HPA019445, HPA076421" Enhanced Approved Vesicles NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 35: Neurons - Synaptic function & neurogenesis" 5 Vesicles "HPA014551: , HPA019445: , HPA076421: " "unprognostic (1.11e-1)" "unprognostic (2.74e-2)" "unprognostic (2.15e-1)" "potential prognostic favorable (1.96e-5)" "unprognostic (1.92e-2)" KCNH2 "erg1, HERG, Kv11.1, LQT2" ENSG00000055118 "Potassium voltage-gated channel subfamily H member 2" Q12809 7 150944961-150978321 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Deafness, Disease variant, FDA approved drug targets, Long QT syndrome, Short QT syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 39.0;pituitary gland: 41.5" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 63.8;Corticotrophs: 49.9;Erythrocyte progenitors: 263.5;Gonadotrophs: 66.4;Lactotrophs: 46.3;Megakaryocyte-Erythroid progenitors: 42.7;Retinal amacrine cells: 42.2;Retinal bipolar cells: 177.1;Sertoli cells: 67.5;Somatotrophs: 39.1;Thyrotrophs: 42.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Leukemia: 23.5;Neuroblastoma: 41.8" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Adrenal gland - Adrenal medulla cells, Heart muscle - Cardiomyocytes, Lung - Fibroblasts_1, Pancreas - Alpha cells, Pancreas - Beta cells, Prostate - Smooth muscle cells, Skin - Smooth muscle cells, Stomach - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 67: Testis - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 11 "unprognostic (1.37e-1)" "unprognostic (2.72e-1)" "unprognostic (1.31e-1)" "unprognostic (4.54e-3)" "unprognostic (5.49e-2)" "unprognostic (2.50e-1)" "unprognostic (1.32e-2)" "unprognostic (3.84e-1)" "unprognostic (9.34e-2)" "unprognostic (2.44e-1)" "unprognostic (2.61e-3)" "unprognostic (3.93e-2)" "potential prognostic favorable (3.21e-4)" "unprognostic (1.26e-1)" "unprognostic (4.68e-2)" "unprognostic (5.02e-1)" "unprognostic (1.84e-1)" "unprognostic (1.45e-3)" "unprognostic (1.28e-1)" "unprognostic (3.42e-1)" "unprognostic (1.75e-1)" "unprognostic (4.08e-2)" "unprognostic (9.69e-2)" "unprognostic (6.13e-2)" "unprognostic (5.49e-2)" KCNH3 "BEC1, elk2, Kv12.2" ENSG00000135519 "Potassium voltage-gated channel subfamily H member 3" Q9ULD8 12 49539030-49558337 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 12 "brain: 71.6;pituitary gland: 19.7" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 50.0;Brain inhibitory neurons: 32.5;Corticotrophs: 21.1;Ependymal cells: 21.1;Epididymal clear cells: 51.0;Epididymal efferent duct ciliated cells: 28.5;Fallopian tube ciliated cells: 26.2;Gonadotrophs: 37.7;Neutrophils: 20.7;Podocytes: 22.7;Respiratory ciliated cells: 35.7" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 6.4" "Group enriched" "Detected in all" 6 "amygdala: 74.5;basal ganglia: 55.7;cerebral cortex: 82.6;hippocampal formation: 75.7;white matter: 63.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 5.5" "Breast - Breast myoepithelial cells, Lung - Respiratory ciliated cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 35: Neurons - Synaptic function & neurogenesis" "unprognostic (2.01e-2)" "unprognostic (4.08e-2)" "unprognostic (9.71e-2)" "unprognostic (1.20e-1)" "unprognostic (1.25e-1)" "unprognostic (2.69e-1)" "unprognostic (9.35e-2)" "unprognostic (2.08e-1)" KCNH4 "elk1, Kv12.3" ENSG00000089558 "Potassium voltage-gated channel subfamily H member 4" Q9UQ05 17 42156891-42181142 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "brain: 6.9" "Cell type enriched" "Detected in some" 4 "Brain inhibitory neurons: 36.0" "Group enriched" "Detected in many" 5 "eccentric medium spiny neuron: 65.1;medium spiny neuron: 116.1;upper-layer intratelencephalic: 31.8" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "basal ganglia: 33.1;cerebral cortex: 9.7;thalamus: 8.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 3.5;Neuroblastoma: 6.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" KCNH5 "eag2, H-EAG2, hEAG2, Kv10.2" ENSG00000140015 "Potassium voltage-gated channel subfamily H member 5" Q8NCM2 14 62699464-63102037 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Calmodulin-binding, Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.1;retina: 4.1" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 127.6;Brain excitatory neurons: 89.8;Brain inhibitory neurons: 87.8;Choroid plexus epithelial cells: 357.0;Corticotrophs: 416.1;Mesothelial cells: 111.8;Oligodendrocyte progenitor cells: 119.3;Other brain neurons: 90.6;Pituitary stem cells: 95.2;Retinal amacrine cells: 498.5;Retinal bipolar cells: 417.9;Retinal pigment epithelial cells: 439.1" "Cell type enhanced" "Detected in all" "thalamic excitatory: 525.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 1.4;cervical cancer: 1.2" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Corticotropes, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA030487, HPA072351" Uncertain Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 1 Centrosome "Nucleoplasm, Cytosol" "HPA030487: , HPA072351: " "unprognostic (1.56e-1)" KCNH6 "erg2, HERG2, Kv11.2" ENSG00000173826 "Potassium voltage-gated channel subfamily H member 6" Q9H252 17 63523334-63548977 "FDA approved drug targets, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 4.5;kidney: 6.7;pituitary gland: 5.3;prostate: 3.9;retina: 4.1" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 14.5;Enterocytes: 54.5;Neuroendocrine cells: 42.3;Pancreatic islet cells: 27.6;Prostatic glandular cells: 27.4;Proximal tubule cells: 95.4;Retinal bipolar cells: 48.2" "Cell type enhanced" "Detected in many" "mammillary body: 6.3;splatter: 5.7" "Cancer enhanced" "Detected in some" "Prostate Adenocarcinoma (TCGA): 8.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 6.2;lung cancer: 9.7;prostate cancer: 5.3" "Adrenal gland - Adrenal medulla cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Pancreas - Alpha cells, Pituitary gland - Corticotropes, Prostate - Prostate glandular cells, Stomach - Gastric enteroendocrine cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "medulla oblongata: 1.4;olfactory bulb: 3.2;spinal cord: 3.2" HPA061704 Approved NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 49: Hindbrain - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "HPA061704: " "unprognostic (1.22e-2)" "unprognostic (3.70e-3)" "unprognostic (1.25e-1)" "unprognostic (7.56e-2)" "unprognostic (1.92e-2)" "potential prognostic favorable (4.51e-4)" "unprognostic (3.49e-1)" "unprognostic (3.10e-1)" KCNH7 "erg3, HERG3, Kv11.3" ENSG00000184611 "Potassium voltage-gated channel subfamily H member 7" Q9NS40 2 162371407-162838767 "FDA approved drug targets, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.4;retina: 1.4" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 529.4;Brain inhibitory neurons: 325.6;Corticotrophs: 928.1;Distal convoluted tubule cells: 184.3;Late spermatids: 359.2;Other brain neurons: 518.4;Retinal bipolar cells: 457.3;Retinal ganglion cells: 154.5;Retinal horizontal cells: 969.6" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 2.0" "Adipose visceral - Neutrophils, Lung - Neutrophils_2, Pituitary gland - Corticotropes, Spleen - Neutrophils_2, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 5 "amygdala: 21.6;cerebral cortex: 85.1;hippocampal formation: 55.9;olfactory bulb: 53.9" HPA018039 Uncertain NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 109: Neurons - Neuronal signaling" "HPA018039: " "unprognostic (4.19e-3)" KCNH8 "elk3, Kv12.1" ENSG00000183960 "Potassium voltage-gated channel subfamily H member 8" Q96L42 3 19148510-19535642 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 10.2;pituitary gland: 10.5;retina: 3.2" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 510.6;Corticotrophs: 377.5;Lactotrophs: 885.9;Oligodendrocyte progenitor cells: 436.4;Oligodendrocytes: 1012.7;Sertoli cells: 233.7;Somatotrophs: 1041.5;Thyrotrophs: 745.9" "Group enriched" "Detected in many" 9 "committed oligodendrocyte precursor: 514.5;oligodendrocyte: 1153.5;oligodendrocyte precursor cell: 520.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.4" "Lineage enriched" "Detected in single" 4 "B-cells: 1.4" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 4.0;Neuroblastoma: 2.4" "Colon - Enteric glia cells, Skin - Outer root sheath cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA016586, HPA077537, HPA077773" Approved Supported "Plasma membrane" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" "Plasma membrane" "HPA016586: , HPA077537: , HPA077773: " "unprognostic (6.89e-2)" "unprognostic (2.26e-2)" "unprognostic (5.30e-2)" "unprognostic (1.29e-1)" "unprognostic (1.63e-3)" "unprognostic (1.38e-3)" "unprognostic (1.42e-1)" "unprognostic (7.77e-2)" "unprognostic (1.99e-1)" "unprognostic (3.07e-2)" KCNIP1 KCHIP1 ENSG00000182132 "Potassium voltage-gated channel interacting protein 1" Q9NZI2 5 170353487-170736632 "Predicted intracellular proteins, Transporters" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 52.1;epididymis: 20.4" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 138.3;Bergmann glia: 190.3;Brain inhibitory neurons: 177.3;Cardiomyocytes: 430.7;Leydig cells: 319.2;Microglia: 600.4;Oligodendrocyte progenitor cells: 422.5;Peritubular myoid cells: 543.9;Renal connecting tubule cells: 232.1;Retinal horizontal cells: 456.8" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 792.5;fibroblast: 728.7" "Cancer enriched" "Detected in many" 13 "Glioblastoma Multiforme (TCGA): 73.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney cancer: 24.0" "Adrenal gland - Adrenal medulla cells, Pancreas - Alpha cells, Skeletal muscle - Fibroblasts, Skin - Fibroblasts_1, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022864, HPA066717" Uncertain Approved Vesicles NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 7 Vesicles "HPA022864: , HPA066717: " "unprognostic (8.76e-3)" "unprognostic (7.03e-2)" "unprognostic (5.99e-3)" "unprognostic (1.63e-2)" "unprognostic (1.40e-1)" "unprognostic (8.84e-2)" "unprognostic (7.84e-3)" "unprognostic (1.74e-1)" "unprognostic (3.03e-2)" "unprognostic (6.87e-2)" "unprognostic (3.31e-1)" "unprognostic (2.61e-1)" "unprognostic (1.15e-1)" KCNIP2 KCHIP2 ENSG00000120049 "Potassium voltage-gated channel interacting protein 2" Q9NS61 10 101825974-101843920 "Predicted intracellular proteins, Transporters" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 213.5;brain: 247.2;heart muscle: 286.7" "Cell type enhanced" "Detected in many" "Adipocytes: 230.9;Brain excitatory neurons: 32.5;Brain inhibitory neurons: 87.3;Cardiomyocytes: 61.3;Cone photoreceptor cells: 26.9;Retinal amacrine cells: 24.4;Retinal bipolar cells: 45.5;Retinal horizontal cells: 28.0" "Cell type enhanced" "Detected in all" "medium spiny neuron: 158.2" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 10.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.5" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Minor Salivary Gland - Adipocytes (Minor salivary gland), Skeletal muscle - Fibroblasts, Skin - Adipocytes (Skin)" "Group enriched" "Detected in all" 4 "amygdala: 96.9;basal ganglia: 235.0;cerebral cortex: 106.9;hippocampal formation: 142.7;olfactory bulb: 144.0" "Low region specificity" "Detected in all" HPA066717 Approved Vesicles NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 35: Non-specific - Mixed function" "Cluster 33: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 89: Adipocytes - Lipid metabolism" 7 Vesicles "HPA066717: " "unprognostic (1.85e-2)" "unprognostic (4.41e-2)" "unprognostic (1.70e-3)" "unprognostic (1.98e-2)" "unprognostic (1.18e-3)" "unprognostic (3.80e-2)" "unprognostic (1.04e-1)" "unprognostic (2.89e-2)" "potential prognostic unfavorable (2.01e-5)" "unprognostic (1.00e-1)" "unprognostic (1.68e-1)" "unprognostic (7.02e-2)" "unprognostic (2.80e-2)" "unprognostic (2.25e-1)" "unprognostic (4.35e-2)" "unprognostic (8.69e-2)" "unprognostic (1.07e-1)" "unprognostic (3.92e-1)" "unprognostic (2.65e-2)" "potential prognostic unfavorable (4.49e-4)" "unprognostic (8.90e-2)" "unprognostic (5.89e-2)" "unprognostic (3.02e-1)" "unprognostic (9.69e-2)" "unprognostic (6.28e-2)" "unprognostic (1.76e-2)" "unprognostic (1.06e-2)" KCNIP3 "CSEN, DREAM, KCHIP3" ENSG00000115041 "Potassium voltage-gated channel interacting protein 3" Q9Y2W7 2 95297327-95386077 "Predicted intracellular proteins, Transporters" "Apoptosis, Ion transport, Potassium transport, Transcription, Transcription regulation, Transport" "Ion channel, Potassium channel, Repressor, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.4;lymphoid tissue: 22.9;parathyroid gland: 25.1" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 25.8;Lactotrophs: 43.3;Leydig cells: 45.0;Melanocytes: 31.6;Oligodendrocyte progenitor cells: 103.0;Peritubular myoid cells: 61.9;Salivary duct cells: 30.0" "Cell type enhanced" "Detected in many" "oligodendrocyte precursor cell: 122.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066717, HPA069797" Enhanced Approved Vesicles "Intracellular and membrane" Transport NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 20 Vesicles "HPA066717: , HPA069797: " "unprognostic (2.65e-1)" "unprognostic (6.73e-2)" "unprognostic (1.65e-1)" "unprognostic (1.31e-1)" "unprognostic (4.56e-1)" "potential prognostic favorable (3.05e-4)" "unprognostic (3.78e-1)" "unprognostic (1.85e-1)" "potential prognostic unfavorable (2.90e-4)" "unprognostic (1.62e-2)" "unprognostic (1.06e-2)" "unprognostic (1.53e-1)" "unprognostic (2.00e-1)" "unprognostic (2.23e-1)" "unprognostic (9.14e-2)" "unprognostic (8.27e-2)" "unprognostic (2.48e-2)" "unprognostic (2.10e-2)" "unprognostic (1.42e-1)" "unprognostic (7.53e-2)" "unprognostic (6.01e-2)" "unprognostic (4.62e-2)" "unprognostic (1.80e-1)" "unprognostic (1.32e-1)" "unprognostic (2.44e-2)" "unprognostic (1.21e-2)" "unprognostic (4.89e-2)" KCNIP4 "CALP, KCHIP4, MGC44947" ENSG00000185774 "Potassium voltage-gated channel interacting protein 4" Q6PIL6 4 20728606-21948772 "Predicted intracellular proteins, Transporters" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.4;retina: 16.8" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 9555.2;Brain inhibitory neurons: 7943.7;Distal convoluted tubule cells: 2683.7;Gonadotrophs: 2279.8;Loop of henle epithelial cells: 2854.5;Oligodendrocyte progenitor cells: 6714.5;Other brain neurons: 4307.6;Renal connecting tubule cells: 4135.5;Retinal amacrine cells: 5853.0;Retinal bipolar cells: 4051.3;Retinal ganglion cells: 2456.7;Thyrotrophs: 7154.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 9.2;Kidney Renal Clear Cell Carcinoma (TCGA): 7.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Neuroblastoma: 1.3" "Pituitary gland - Thyrotropes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022862, HPA066717" Supported Approved Vesicles NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 14: Neurons - Synaptic function" "Cluster 24: Non-specific - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" 12 Vesicles "HPA022862: , HPA066717: " "unprognostic (2.52e-1)" "unprognostic (1.39e-1)" "unprognostic (5.07e-2)" "unprognostic (6.49e-2)" "validated prognostic favorable (1.15e-5)" "validated prognostic favorable (2.08e-4)" "unprognostic (3.58e-2)" "unprognostic (2.75e-1)" "unprognostic (1.43e-1)" "unprognostic (2.51e-1)" KCNJ1 "Kir1.1, ROMK1" ENSG00000151704 "Potassium inwardly rectifying channel subfamily J member 1" P48048 11 128836315-128867373 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Bartter syndrome, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 41 "kidney: 184.8" "Group enriched" "Detected in some" 6 "Distal convoluted tubule cells: 235.2;Loop of henle epithelial cells: 159.3;Renal connecting tubule cells: 191.8" "Cell type enhanced" "Detected in many" "amygdala excitatory: 6.9;medium spiny neuron: 9.6" "Group enriched" "Detected in some" 7 "Kidney Chromophobe (TCGA): 34.1;Kidney Renal Papillary Cell Carcinoma (TCGA): 14.0" "Region enhanced" "Detected in some" "basal ganglia: 3.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Ascending Loop of Henle cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA026962 Enhanced NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 33: Neurons - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 3 "HPA026962: " "unprognostic (2.21e-1)" "unprognostic (4.88e-2)" "unprognostic (3.75e-2)" "unprognostic (3.99e-1)" "unprognostic (4.10e-1)" "unprognostic (1.42e-1)" KCNJ10 "Kir1.2, Kir4.1" ENSG00000177807 "Potassium inwardly rectifying channel subfamily J member 10" P78508 1 159998651-160070160 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Deafness, Disease variant, Epilepsy, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 114.4;kidney: 26.1;retina: 34.0" "Cell type enhanced" "Detected in many" "Astrocytes: 106.7;Bergmann glia: 88.1;Distal convoluted tubule cells: 44.2;Ependymal cells: 32.3;Epicardial cells: 125.1;Kupffer cells: 40.0;Müller glia: 87.4;Oligodendrocyte progenitor cells: 60.6;Oligodendrocytes: 109.5" "Group enriched" "Detected in many" 16 "astrocyte: 115.7;Bergmann glia: 102.9;committed oligodendrocyte precursor: 69.0;ependymal cell: 35.9;oligodendrocyte: 141.2;oligodendrocyte precursor cell: 67.7" "Cancer enriched" "Detected in some" 6 "Glioblastoma Multiforme (TCGA): 42.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "skin cancer: 2.0" "Kidney - Ascending Loop of Henle cells, Liver - Kupffer cells, Spleen - Macrophages, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078302 Enhanced NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 28: Astrocytes - Homeostasis & neuron support" 10 "HPA078302: " "unprognostic (1.18e-1)" "unprognostic (2.22e-1)" "unprognostic (3.38e-1)" "unprognostic (1.34e-1)" "unprognostic (8.30e-2)" "unprognostic (2.23e-1)" "unprognostic (5.43e-2)" "unprognostic (5.48e-2)" "unprognostic (1.49e-1)" "unprognostic (2.96e-1)" KCNJ11 "BIR, Kir6.2" ENSG00000187486 "Potassium inwardly rectifying channel subfamily J member 11" Q14654 11 17365172-17389331 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Diabetes mellitus, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 106.1;tongue: 40.3" "Cell type enriched" "Detected in many" 15 "Epicardial cells: 600.4" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 25.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Prostate - Prostate glandular cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048891 Approved NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 37: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 3 "HPA048891: " "unprognostic (2.43e-2)" "unprognostic (1.26e-2)" "unprognostic (2.81e-1)" "unprognostic (3.87e-2)" "unprognostic (1.90e-2)" "unprognostic (1.72e-1)" "unprognostic (3.31e-1)" "unprognostic (4.16e-3)" "unprognostic (6.48e-2)" "unprognostic (1.32e-1)" "unprognostic (1.88e-2)" "unprognostic (1.38e-1)" "unprognostic (2.69e-1)" "potential prognostic unfavorable (8.17e-5)" "unprognostic (4.04e-2)" "unprognostic (1.07e-2)" "unprognostic (6.87e-2)" "unprognostic (1.42e-1)" "unprognostic (1.89e-2)" "unprognostic (7.25e-3)" "unprognostic (9.06e-2)" "unprognostic (4.62e-3)" "unprognostic (6.18e-2)" "unprognostic (4.41e-3)" "unprognostic (2.17e-2)" "unprognostic (3.33e-2)" "unprognostic (2.69e-2)" "unprognostic (2.44e-2)" "unprognostic (1.20e-1)" "unprognostic (2.00e-1)" KCNJ12 "hIRK1, IRK2, KCNJN1, Kir2.2, Kir2.2v" ENSG00000184185 "Potassium inwardly rectifying channel subfamily J member 12" Q14500 17 21376357-21419870 "FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 41.8;skeletal muscle: 64.7;tongue: 24.1" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 31.9;Brain excitatory neurons: 19.2;Conjunctival goblet cells: 29.1;Endometrial secretory cells: 31.8;Müller glia: 13.3;Myonuclei: 15.3;Respiratory ionocytes: 15.2;Retinal amacrine cells: 15.4;Retinal horizontal cells: 74.1;Salivary ionocytes: 13.0" "Cell type enhanced" "Detected in many" "upper rhombic lip: 44.5" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "cerebellum: 58.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes" HPA027021 Approved Uncertain "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 15: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 13 "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA027021: " "unprognostic (1.01e-3)" "unprognostic (2.04e-1)" "unprognostic (3.70e-2)" "unprognostic (5.14e-3)" "unprognostic (4.92e-2)" "unprognostic (1.56e-1)" "unprognostic (2.78e-3)" "unprognostic (1.35e-1)" "unprognostic (4.27e-2)" "unprognostic (9.21e-2)" KCNJ13 "Kir1.4, Kir7.1, LCA16" ENSG00000115474 "Potassium inwardly rectifying channel subfamily J member 13" O60928 2 232765802-232776565 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Cataract, Disease variant, Leber congenital amaurosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "choroid plexus: 165.9;intestine: 85.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 62.9;Choroid plexus epithelial cells: 154.5;Enteric transient amplifying cells: 36.9;Enterocytes: 119.0;Epicardial cells: 79.6;Melanocytes: 38.6;Retinal pigment epithelial cells: 68.2" "Cell type enriched" "Detected in all" 31 "choroid plexus epithelial cell: 238.7" "Group enriched" "Detected in some" 5 "Kidney Chromophobe (TCGA): 4.1;Kidney Renal Papillary Cell Carcinoma (TCGA): 3.8;Skin Cutaneous Melanoma (TCGA): 12.0" "Region enriched" "Detected in all" 15 "choroid plexus: 342.3" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in single" "Kidney cancer: 1.1" "Kidney - Ascending Loop of Henle cells, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051609 Approved "Nuclear membrane,Plasma membrane" NA NA "Cluster 32: Basophils - Transcription" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 101: Choroid plexus epithelial cells - Ion transport" "Nuclear membrane" "Plasma membrane" "HPA051609: " "unprognostic (1.97e-2)" "unprognostic (3.23e-2)" "unprognostic (2.59e-1)" "unprognostic (8.71e-2)" "unprognostic (4.82e-2)" "unprognostic (2.75e-3)" "unprognostic (6.18e-3)" "unprognostic (2.20e-2)" KCNJ14 "IRK4, Kir2.4" ENSG00000182324 "Potassium inwardly rectifying channel subfamily J member 14" Q9UNX9 19 48455574-48466980 "FDA approved drug targets, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "retina: 54.4" "Cell type enriched" "Detected in many" 13 "Rod photoreceptor cells: 213.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 79: Photoreceptor cells - Phototransduction" "unprognostic (1.06e-2)" "unprognostic (4.77e-2)" "unprognostic (9.62e-2)" "unprognostic (3.84e-3)" "potential prognostic unfavorable (1.04e-4)" "unprognostic (2.74e-1)" "unprognostic (1.03e-1)" "unprognostic (2.37e-3)" "unprognostic (1.65e-2)" "unprognostic (1.39e-2)" "unprognostic (7.81e-3)" "unprognostic (5.88e-2)" "unprognostic (6.69e-3)" "unprognostic (1.75e-2)" "unprognostic (3.70e-3)" "unprognostic (3.25e-1)" "unprognostic (7.12e-2)" "unprognostic (2.40e-1)" "unprognostic (4.01e-2)" "unprognostic (1.18e-2)" "unprognostic (7.93e-2)" KCNJ15 "IRKK, Kir1.3, Kir4.2" ENSG00000157551 "Potassium inwardly rectifying channel subfamily J member 15" Q99712 21 38155549-38307357 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 225.4;thyroid gland: 121.2" "Group enriched" "Detected in many" 4 "Neutrophils: 2664.8;Proximal tubule cells: 1013.7" "Cell type enhanced" "Detected in some" "deep-layer near-projecting: 1.5;fibroblast: 1.2;hippocampal CA1-3: 1.1" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 102.3;Thyroid Carcinoma (TCGA): 124.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 21 "neutrophil: 398.0" "Lineage enriched" "Detected in many" 21 "granulocytes: 398.0" "Cancer enhanced" "Detected in many" "Bladder cancer: 22.2;head and neck cancer: 20.7" "Heart muscle - Neutrophils, Kidney - Proximal tubular cells, Lung - Alveolar cells type 2, Prostate - Urothelial cells, Spleen - Neutrophils_2, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA016702 Approved Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 72: Kidney - Transmembrane transport" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 24: Neutrophils - Innate immunity signal integration" 3 "Plasma membrane" "Vesicles, Cytosol" "HPA016702: " "unprognostic (2.35e-2)" "unprognostic (1.63e-2)" "unprognostic (1.19e-1)" "unprognostic (9.52e-2)" "unprognostic (8.13e-2)" "unprognostic (2.25e-1)" "unprognostic (1.56e-3)" "unprognostic (8.50e-2)" "validated prognostic favorable (1.05e-11)" "validated prognostic favorable (2.35e-4)" "potential prognostic favorable (1.28e-4)" "unprognostic (1.65e-1)" "unprognostic (4.44e-3)" "unprognostic (9.52e-2)" "unprognostic (1.48e-1)" "unprognostic (7.23e-2)" "potential prognostic unfavorable (5.68e-4)" "unprognostic (5.55e-2)" "unprognostic (2.00e-2)" "unprognostic (8.87e-3)" "unprognostic (2.39e-2)" "unprognostic (1.53e-2)" "unprognostic (8.79e-2)" "unprognostic (4.27e-3)" "unprognostic (1.14e-1)" "unprognostic (1.57e-1)" "unprognostic (5.54e-3)" KCNJ16 "BIR9, Kir5.1" ENSG00000153822 "Potassium inwardly rectifying channel subfamily J member 16" Q9NPI9 17 70053429-70135608 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 182.2;parathyroid gland: 251.5;thyroid gland: 130.4" "Cell type enhanced" "Detected in many" "Bergmann glia: 197.9;Conjunctival goblet cells: 171.8;Distal convoluted tubule cells: 1336.5;Loop of henle epithelial cells: 481.0;Parietal cells: 221.0;Proximal tubule cells: 680.6;Renal collecting duct principal cells: 554.4;Renal connecting tubule cells: 765.3" "Group enriched" "Detected in many" 4 "astrocyte: 74.6;Bergmann glia: 224.9;ependymal cell: 117.0;oligodendrocyte precursor cell: 101.0" "Group enriched" "Detected in many" 7 "Kidney Renal Clear Cell Carcinoma (TCGA): 68.8;Kidney Renal Papillary Cell Carcinoma (TCGA): 148.5;Thyroid Carcinoma (TCGA): 191.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "neutrophil: 1.6" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.6" "Cancer enhanced" "Detected in many" "Kidney cancer: 26.7;Sarcoma: 16.6" "Adipose visceral - Mesothelial cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary gland ductal cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059563 Approved Uncertain Vesicles NA NA "Cluster 33: Thyroid gland - Tissue development" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 2 Vesicles "HPA059563: " "unprognostic (2.08e-1)" "unprognostic (4.43e-3)" "unprognostic (4.98e-2)" "unprognostic (9.26e-3)" "unprognostic (1.90e-2)" "potential prognostic favorable (6.16e-7)" "unprognostic (1.39e-1)" "potential prognostic favorable (1.77e-5)" "unprognostic (8.04e-3)" "unprognostic (2.81e-1)" "unprognostic (2.04e-1)" "unprognostic (3.10e-1)" "unprognostic (4.17e-2)" "unprognostic (1.29e-2)" "unprognostic (7.15e-2)" "unprognostic (2.08e-1)" "unprognostic (5.03e-2)" "unprognostic (2.52e-1)" "unprognostic (1.88e-1)" "unprognostic (7.71e-2)" "unprognostic (3.64e-3)" "unprognostic (1.76e-1)" KCNJ18 "KIR2.6, TTPP2" ENSG00000260458 "Potassium inwardly rectifying channel subfamily J member 18" B7U540 17 21692523-21704612 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "skin 1: 7.3" "Cell type enhanced" "Detected in some" "Conjunctival goblet cells: 1.9;Suprabasal keratinocytes: 1.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 1.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA027021 Uncertain Uncertain "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 37: Skin - Keratinization" "Cluster 7: Liver cancer - Metabolism" "Cluster 26: Keratinocytes - Keratinization" 3 "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA027021: " "unprognostic (2.36e-1)" KCNJ2 "IRK1, Kir2.1, LQT7" ENSG00000123700 "Potassium inwardly rectifying channel subfamily J member 2" P63252 17 70168673-70180044 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Atrial fibrillation, Disease variant, FDA approved drug targets, Long QT syndrome, Short QT syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 33.9" "Cell type enhanced" "Detected in many" "Breast lactating cells: 44.8;Cardiomyocytes: 106.8;Kupffer cells: 92.2;Medullary thymic epithelial cells: 43.2;Myonuclei: 73.5;Neutrophils: 312.6;Oligodendrocytes: 159.0;Retinal horizontal cells: 152.3;Thymic myoid cells: 44.9" "Cell type enhanced" "Detected in many" "oligodendrocyte: 237.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 30.7" "Lineage enriched" "Detected in many" 4 "granulocytes: 30.7" "Cancer enhanced" "Detected in many" "Rhabdoid: 11.3" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029109 Approved NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 10 "HPA029109: " "unprognostic (3.15e-1)" "unprognostic (4.61e-1)" "unprognostic (2.15e-2)" "unprognostic (6.16e-2)" "unprognostic (3.32e-1)" "unprognostic (1.54e-1)" "unprognostic (1.69e-1)" "unprognostic (8.74e-2)" "unprognostic (4.41e-2)" "unprognostic (1.39e-1)" "unprognostic (8.64e-2)" "unprognostic (2.65e-3)" "unprognostic (3.45e-2)" "unprognostic (1.37e-1)" "unprognostic (1.34e-1)" "unprognostic (6.78e-2)" "unprognostic (1.98e-1)" "unprognostic (8.54e-2)" "unprognostic (1.72e-1)" "unprognostic (1.93e-2)" "unprognostic (1.31e-2)" "unprognostic (1.14e-1)" "unprognostic (1.69e-1)" "unprognostic (1.20e-2)" "unprognostic (7.87e-2)" "unprognostic (2.89e-2)" "unprognostic (5.65e-2)" "unprognostic (7.91e-2)" "unprognostic (2.12e-2)" KCNJ3 "GIRK1, KGA, Kir3.1" ENSG00000162989 "Potassium inwardly rectifying channel subfamily J member 3" P48549 2 154697855-154858354 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 39.4" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 578.5;Brain inhibitory neurons: 266.8;Choroid plexus epithelial cells: 560.5;Corticotrophs: 996.3;Ependymal cells: 262.3;Lactotrophs: 642.9;Pituicytes/FSCs: 355.3;Renal collecting duct intercalated cells: 328.1;Renal collecting duct principal cells: 237.3;Renal connecting tubule cells: 337.7;Retinal amacrine cells: 271.3;Retinal horizontal cells: 565.0;Somatotrophs: 401.4;Thyrotrophs: 723.5" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 21.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 2.9" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal medulla cells, Kidney - Ascending Loop of Henle cells, Liver - Hepatocytes, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024231, HPA064138" Uncertain Approved "Plasma membrane,Mitochondria" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 35: Non-specific - DNA binding" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 2 Mitochondria "Plasma membrane" "HPA024231: , HPA064138: " "unprognostic (1.63e-1)" "unprognostic (2.04e-1)" "unprognostic (7.17e-2)" "unprognostic (1.54e-2)" "unprognostic (8.51e-2)" "unprognostic (3.52e-2)" "unprognostic (2.23e-1)" "potential prognostic favorable (8.20e-9)" "unprognostic (9.44e-3)" "unprognostic (5.39e-2)" "unprognostic (1.18e-1)" "unprognostic (1.42e-1)" "unprognostic (9.15e-2)" "unprognostic (1.02e-2)" "unprognostic (3.22e-1)" "unprognostic (2.83e-1)" "unprognostic (4.09e-2)" "unprognostic (1.27e-3)" "unprognostic (2.30e-1)" "unprognostic (1.04e-1)" KCNJ4 "HIR, hIRK2, HRK1, IRK3, Kir2.3" ENSG00000168135 "Potassium inwardly rectifying channel subfamily J member 4" P48050 22 38426327-38455199 "FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 18 "brain: 82.7;heart muscle: 31.7" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 11.0;Brain inhibitory neurons: 12.5;Cardiomyocytes: 8.5;Endometrial secretory cells: 2.6;Ependymal cells: 11.7;Müller glia: 6.9;Platelets: 14.2;Retinal horizontal cells: 4.0" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Glioblastoma Multiforme (TCGA): 3.6;Kidney Renal Papillary Cell Carcinoma (TCGA): 2.4;Liver Hepatocellular Carcinoma (TCGA): 2.5;Uterine Corpus Endometrial Carcinoma (TCGA): 1.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 3.3" "Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 15 "amygdala: 29.3;basal ganglia: 68.9;cerebral cortex: 74.2;hippocampal formation: 61.3;olfactory bulb: 76.3" HPA003270 Uncertain Vesicles NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 35: Neurons - Synaptic function & neurogenesis" 9 Vesicles "HPA003270: " "unprognostic (7.27e-2)" "unprognostic (4.18e-1)" "unprognostic (2.14e-2)" "unprognostic (9.62e-3)" "unprognostic (7.65e-2)" "unprognostic (1.01e-3)" "unprognostic (1.76e-2)" KCNJ5 "CIR, GIRK4, KATP1, Kir3.4, LQT13" ENSG00000120457 "Potassium inwardly rectifying channel subfamily J member 5" P48544 11 128891356-128921163 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Cancer-related genes, Disease variant, Long QT syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 60.7;pancreas: 19.2" "Cell type enhanced" "Detected in some" "Adrenal cortex cells: 123.7;Adrenal medulla cells: 31.9;Cardiomyocytes: 48.7;Hofbauer cells: 133.7;Lactotrophs: 39.5;Late spermatids: 24.1;Macrophages: 21.4;Microglia: 19.8;Somatotrophs: 34.1;Thyrotrophs: 27.4" "Group enriched" "Detected in many" 5 "central nervous system macrophage: 31.9;MGE interneuron: 8.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adrenal gland - Adrenal cortex cells, Colon - Colon enteroendocrine cells, Pituitary gland - Lactotropes" "Group enriched" "Detected in many" 6 "basal ganglia: 2.9;hypothalamus: 6.8;midbrain: 1.9;thalamus: 3.6" "Low region specificity" "Detected in all" "HPA014722, HPA017353, CAB022569" Approved NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 18: Adrenal cortex cells - Steroidogensis" 4 "CAB022569: , HPA014722: , HPA017353: " "unprognostic (1.05e-1)" "unprognostic (2.71e-2)" "unprognostic (1.74e-1)" "unprognostic (1.07e-2)" "unprognostic (7.63e-2)" "unprognostic (5.23e-2)" "unprognostic (1.11e-1)" "unprognostic (6.74e-2)" "unprognostic (9.08e-2)" "unprognostic (1.59e-2)" "unprognostic (6.52e-3)" "potential prognostic favorable (6.61e-4)" "unprognostic (2.08e-1)" "unprognostic (1.35e-2)" "potential prognostic favorable (4.92e-4)" "unprognostic (1.86e-1)" "unprognostic (8.28e-2)" "unprognostic (4.13e-2)" "unprognostic (3.51e-1)" "unprognostic (1.16e-3)" "unprognostic (3.43e-1)" "unprognostic (2.99e-1)" "unprognostic (1.25e-1)" "unprognostic (1.56e-2)" "unprognostic (1.92e-1)" "unprognostic (1.17e-1)" "unprognostic (1.73e-1)" "unprognostic (5.27e-2)" "unprognostic (4.15e-1)" KCNJ6 "BIR1, GIRK2, hiGIRK2, KATP2, KCNJ7, Kir3.2" ENSG00000157542 "Potassium inwardly rectifying channel subfamily J member 6" P48051 21 37607373-38121345 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Congenital generalized lipodystrophy, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.0;pituitary gland: 1.7" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 251.4;Brain inhibitory neurons: 118.6;Corticotrophs: 396.4;Lactotrophs: 228.1;Neuroendocrine cells: 126.9;Oligodendrocyte progenitor cells: 103.7;Oocytes: 128.9;Other brain neurons: 166.8;Pancreatic islet cells: 359.1;Retinal amacrine cells: 178.2;Retinal horizontal cells: 434.7;Somatotrophs: 274.9;Thyrotrophs: 117.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in single" "Testicular Germ Cell Tumor (TCGA): 1.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.0;eosinophil: 1.3" "Lineage enriched" "Detected in single" 16 "granulocytes: 2.0" "Cancer enhanced" "Detected in some" "Sarcoma: 2.1" "Adrenal gland - Adrenal medulla cells, Pancreas - Alpha cells, Pancreas - Beta cells, Pituitary gland - Corticotropes, Prostate - Prostate glandular cells, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 1: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 35: Neurons - Synaptic function & neurogenesis" 52 "unprognostic (2.09e-1)" "unprognostic (6.98e-2)" "unprognostic (2.29e-2)" "unprognostic (1.44e-1)" KCNJ8 Kir6.1 ENSG00000121361 "Potassium inwardly rectifying channel subfamily J member 8" Q15842 12 21764955-21775600 "Disease related genes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 63.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 30.2;Breast lactating cells: 65.6;Cardiomyocytes: 62.3;Decidual stromal cells: 34.3;Hepatocytes: 26.0;Pancreatic acinar cells: 27.6;Pancreatic islet cells: 21.2;Pericytes: 122.0;Smooth muscle cells: 21.0;Vascular smooth muscle cells: 19.8" "Cell type enriched" "Detected in many" 5 "pericyte: 92.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 15 "eosinophil: 1.5" "Lineage enriched" "Detected in single" 15 "granulocytes: 1.5" "Cancer enhanced" "Detected in many" "Kidney cancer: 6.8;liver cancer: 7.0;Neuroblastoma: 11.5" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Kidney - Fibroblasts, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031066 Uncertain NA NA "Cluster 70: Non-specific - Protein processing" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 34: Testis cancer - Unknown function" "Cluster 110: Mural cells - ECM organization" 3 "HPA031066: " "unprognostic (1.58e-2)" "unprognostic (2.87e-2)" "unprognostic (4.04e-1)" "unprognostic (9.85e-3)" "unprognostic (4.37e-2)" "unprognostic (8.03e-2)" "unprognostic (4.98e-1)" "unprognostic (2.93e-1)" "unprognostic (9.15e-2)" "unprognostic (2.84e-2)" "unprognostic (1.05e-2)" "unprognostic (5.11e-2)" "unprognostic (4.94e-3)" "unprognostic (1.29e-1)" "unprognostic (6.86e-2)" "unprognostic (4.99e-1)" "unprognostic (6.88e-2)" "unprognostic (1.13e-1)" "unprognostic (9.14e-2)" "unprognostic (3.44e-2)" "unprognostic (6.38e-2)" "unprognostic (1.00e-1)" "unprognostic (9.93e-2)" "unprognostic (8.35e-2)" "unprognostic (2.51e-2)" "unprognostic (9.83e-2)" "unprognostic (7.02e-3)" "unprognostic (1.05e-1)" "potential prognostic unfavorable (7.44e-4)" "unprognostic (1.22e-1)" KCNJ9 "GIRK3, Kir3.3" ENSG00000162728 "Potassium inwardly rectifying channel subfamily J member 9" Q92806 1 160081538-160090563 "Essential proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "brain: 69.4" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 10.6;Brain excitatory neurons: 21.9;Brain inhibitory neurons: 14.3;Medullary thymic epithelial cells: 4.8;Oligodendrocytes: 9.8;Other brain neurons: 9.1;Retinal amacrine cells: 12.8;Retinal bipolar cells: 9.8;Retinal ganglion cells: 3.9;Retinal horizontal cells: 8.0" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in single" 47 "Glioblastoma Multiforme (TCGA): 4.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "Neuroblastoma: 3.6" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells, Pituitary gland - Lactotropes, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070478 Enhanced NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 34: Non-specific - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" 1 "HPA070478: " "unprognostic (1.46e-1)" "potential prognostic favorable (4.43e-5)" KCNK1 "DPK, K2p1.1, TWIK-1" ENSG00000135750 "Potassium two pore domain channel subfamily K member 1" O00180 1 233614106-233672514 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 108.6;choroid plexus: 70.0" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 285.7;Endometrial glandular cells: 465.5;Endometrial luminal cells: 337.8;Endometrial secretory cells: 348.4;Esophageal apical cells: 277.2;Foveolar cells: 553.2;Ocular epithelial cells: 300.6" "Cell type enhanced" "Detected in all" "upper rhombic lip: 616.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 70 "plasmacytoid DC: 6.9" "Lineage enriched" "Detected in single" 70 "dendritic cells: 6.9" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2, Stomach - Gastric mucous cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 160.5" "HPA016049, CAB022588" Approved Approved Vesicles NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 27: Cerebellum - Synaptic function" "Cluster 5: Non-specific - Mixed function" "Cluster 20: Myeloma - Immune response" "Cluster 51: Secretory epithelial cells - Mixed function" 52 Vesicles "CAB022588: , HPA016049: " "unprognostic (2.11e-1)" "unprognostic (6.51e-3)" "unprognostic (3.16e-1)" "unprognostic (1.59e-1)" "unprognostic (4.01e-2)" "unprognostic (2.03e-1)" "unprognostic (1.79e-1)" "unprognostic (2.95e-2)" "unprognostic (3.67e-1)" "unprognostic (2.70e-1)" "unprognostic (2.09e-1)" "potential prognostic unfavorable (5.42e-4)" "potential prognostic unfavorable (2.05e-5)" "unprognostic (1.02e-3)" "unprognostic (4.84e-2)" "unprognostic (2.35e-2)" "unprognostic (5.34e-2)" "unprognostic (3.87e-2)" "unprognostic (1.74e-1)" "unprognostic (4.89e-2)" "unprognostic (2.64e-1)" "potential prognostic unfavorable (1.18e-4)" "unprognostic (1.62e-1)" "unprognostic (1.23e-1)" "unprognostic (1.54e-1)" "unprognostic (2.01e-1)" "unprognostic (1.74e-1)" "unprognostic (2.27e-1)" "unprognostic (1.94e-1)" "unprognostic (1.53e-1)" "unprognostic (4.13e-1)" KCNK10 "K2p10.1, PPP1R97, TREK-2, TREK2" ENSG00000100433 "Potassium two pore domain channel subfamily K member 10" P57789 14 88180103-88326907 "Predicted membrane proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.8;intestine: 4.8;kidney: 2.2;stomach 1: 2.5" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 21.3;Basal keratinocytes: 33.9;Brain excitatory neurons: 58.1;Brain inhibitory neurons: 19.9;Oligodendrocyte progenitor cells: 46.5;Oligodendrocytes: 53.0;Other brain neurons: 25.8;Pancreatic islet cells: 24.2;pDCs: 141.9;Proximal tubule cells: 22.6;Thyrotrophs: 24.4" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 2.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 62 "plasmacytoid DC: 10.0" "Lineage enriched" "Detected in single" 100 "dendritic cells: 10.0" "Cancer enhanced" "Detected in some" "Neuroblastoma: 2.5" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Kidney - Proximal tubular cells, Pituitary gland - Thyrotropes, Skin - Outer root sheath cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030462 Approved NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 37: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" "HPA030462: " "unprognostic (6.56e-2)" "unprognostic (5.04e-1)" "unprognostic (2.46e-2)" "unprognostic (3.41e-2)" "unprognostic (3.76e-3)" "unprognostic (6.27e-2)" "unprognostic (2.49e-1)" "unprognostic (2.21e-1)" KCNK12 "K2p12.1, THIK-2, THIK2" ENSG00000184261 "Potassium two pore domain channel subfamily K member 12" Q9HB15 2 47509290-47570985 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 10.2" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 42.8;Brain inhibitory neurons: 26.1;Cone photoreceptor cells: 24.8;Epicardial cells: 31.8;Extravillous trophoblasts: 64.7;Lactotrophs: 49.9;Oocytes: 23.0;Other brain neurons: 23.1;Schwann cells: 21.7;Somatotrophs: 49.6;Thyrotrophs: 38.9" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in single" 7 "Testicular Germ Cell Tumor (TCGA): 1.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Leukemia: 2.5;lymphoma: 1.7;Myeloma: 1.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 37: Neurons - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 2: Cerebellar granular cells - Neuronal signaling" "unprognostic (1.59e-1)" "potential prognostic favorable (3.56e-5)" "unprognostic (5.07e-2)" KCNK13 "K2p13.1, THIK-1, THIK1" ENSG00000152315 "Potassium two pore domain channel subfamily K member 13" Q9HB14 14 90061994-90185853 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "parathyroid gland: 5.7;testis: 9.5" "Cell type enhanced" "Detected in many" "cDC: 75.7;Choroid plexus epithelial cells: 265.0;Ependymal cells: 74.5;Kupffer cells: 53.3;Macrophages: 49.4;Microglia: 266.2;Renal collecting duct principal cells: 74.2;Renal connecting tubule cells: 127.9;Sertoli cells: 300.1" "Group enriched" "Detected in many" 4 "central nervous system macrophage: 330.9;choroid plexus epithelial cell: 190.5" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 8.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.2" "Lineage enhanced" "Detected in single" "dendritic cells: 1.2" "Cancer enhanced" "Detected in single" "testis cancer: 2.7" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Minor Salivary Gland - Macrophages, Spleen - Macrophages, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA003514 Approved Approved "Nuclear speckles,Cell Junctions" NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" "Nuclear speckles, Cell Junctions" "HPA003514: " "unprognostic (2.50e-2)" "unprognostic (2.47e-1)" "unprognostic (1.11e-1)" "unprognostic (2.32e-1)" "unprognostic (2.72e-2)" "unprognostic (1.63e-1)" "unprognostic (3.89e-2)" "unprognostic (1.56e-1)" "unprognostic (3.56e-2)" "unprognostic (2.93e-1)" "potential prognostic unfavorable (9.35e-4)" "unprognostic (5.92e-2)" "unprognostic (7.83e-2)" "unprognostic (2.39e-1)" "unprognostic (4.54e-2)" "unprognostic (3.09e-1)" KCNK15 "dJ781B1.1, K2p15.1, KCNK11, KCNK14, KIAA0237, KT3.3, TASK-5, TASK5" ENSG00000124249 "Potassium two pore domain channel subfamily K member 15" Q9H427 20 44745865-44752313 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "blood vessel: 23.4" "Group enriched" "Detected in many" 4 "Epididymal efferent duct absorptive cells: 133.2;Fallopian secretory cells: 121.5" "Cell type enhanced" "Detected in some" "mammillary body: 4.6" "Cancer enriched" "Detected in many" 5 "Ovary Serous Cystadenocarcinoma (TCGA): 64.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 18 "olfactory bulb: 6.8" "Region enriched" "Detected in single" 8 "olfactory bulb: 5.1" HPA064861 Uncertain NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 7: Liver cancer - Metabolism" "Cluster 108: Fibroblasts - ECM organization" "HPA064861: " "unprognostic (1.58e-1)" "unprognostic (9.31e-2)" "unprognostic (1.28e-1)" "unprognostic (4.63e-3)" "unprognostic (8.06e-3)" "unprognostic (1.22e-1)" "unprognostic (4.74e-2)" "unprognostic (2.52e-1)" "potential prognostic unfavorable (9.35e-4)" "unprognostic (3.32e-3)" "unprognostic (7.15e-2)" "unprognostic (1.52e-1)" "unprognostic (9.72e-2)" "unprognostic (1.03e-1)" "unprognostic (1.15e-1)" "unprognostic (6.22e-3)" "unprognostic (1.43e-1)" KCNK16 "K2p16.1, TALK-1, TALK1" ENSG00000095981 "Potassium two pore domain channel subfamily K member 16" Q96T55 6 39314698-39322968 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "pancreas: 22.4;stomach 1: 9.8" "Cell type enriched" "Detected in some" 17 "Pancreatic islet cells: 80.9" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 16 "Pancreatic Adenocarcinoma (TCGA): 29.2" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 10 "basophil: 2.1" "Lineage enriched" "Detected in single" 10 "granulocytes: 2.1" "Cancer enriched" "Detected in some" 5 "thyroid cancer: 10.8" "Pancreas - Alpha cells, Pancreas - Beta cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 1 "unprognostic (3.28e-2)" "unprognostic (3.27e-1)" "unprognostic (3.34e-1)" KCNK17 "K2p17.1, TALK-2, TALK2, TASK-4, TASK4" ENSG00000124780 "Potassium two pore domain channel subfamily K member 17" Q96T54 6 39299001-39314461 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 26.6" "Cell type enhanced" "Detected in some" "Epididymal efferent duct absorptive cells: 10.3;Fibroblasts: 6.5;Hepatic stellate cells: 19.4;Innate lymphoid cells: 7.0;Pancreatic islet cells: 38.2;pDCs: 33.2;Pericytes: 19.6;Thymocytes: 46.6;Vascular smooth muscle cells: 6.7" "Cell type enriched" "Detected in some" 21 "fibroblast: 115.2" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 4.2" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 34 "plasmacytoid DC: 63.9" "Lineage enriched" "Detected in many" 34 "dendritic cells: 63.9" "Cancer enhanced" "Detected in some" "Leukemia: 5.6;thyroid cancer: 3.4" "Colon - Colon enteroendocrine cells" "Not detected" "Not detected" HPA043892 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 110: Mural cells - ECM organization" "Plasma membrane, Cytosol" Nucleoplasm "HPA043892: " "unprognostic (1.22e-2)" "unprognostic (2.36e-1)" "potential prognostic unfavorable (1.22e-4)" "unprognostic (2.30e-2)" "potential prognostic favorable (4.33e-4)" "potential prognostic favorable (4.67e-5)" "unprognostic (2.58e-1)" "unprognostic (2.76e-2)" "unprognostic (2.08e-2)" "unprognostic (8.90e-3)" "unprognostic (7.89e-2)" "unprognostic (3.70e-2)" "unprognostic (2.14e-1)" "unprognostic (1.35e-1)" KCNK18 "K2p18.1, TRESK, TRESK-2, TRESK2, TRIK" ENSG00000186795 "Potassium two pore domain channel subfamily K member 18" Q7Z418 10 117197489-117210299 "Disease related genes, Potential drug targets, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "choroid plexus: 2.9;hypothalamus: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA044739 Uncertain NA NA "Cluster 36: Choroid plexus - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" "HPA044739: " KCNK2 "K2p2.1, TREK-1" ENSG00000082482 "Potassium two pore domain channel subfamily K member 2" O95069 1 215005775-215237090 "FDA approved drug targets, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "adrenal gland: 50.1" "Cell type enriched" "Detected in some" 4 "Adrenal cortex cells: 288.3" "Cell type enriched" "Detected in many" 4 "fibroblast: 583.5" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 5.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 13.3" "Stomach - Chief cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 33: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 18: Adrenal cortex cells - Steroidogensis" "unprognostic (3.26e-2)" "unprognostic (4.77e-2)" "unprognostic (8.84e-2)" "unprognostic (6.62e-3)" "unprognostic (9.11e-2)" "unprognostic (2.91e-1)" "unprognostic (1.85e-2)" "unprognostic (1.41e-1)" "unprognostic (2.72e-2)" "unprognostic (3.14e-1)" "unprognostic (4.35e-2)" "unprognostic (1.87e-2)" "unprognostic (1.70e-3)" "unprognostic (1.20e-2)" "unprognostic (3.75e-3)" KCNK3 "K2p3.1, TASK, TASK-1, TASK1" ENSG00000171303 "Potassium two pore domain channel subfamily K member 3" O14649 2 26692722-26733420 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Sodium transport, Transport" "Ion channel, Potassium channel, Sodium channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "adrenal gland: 169.1" "Cell type enhanced" "Detected in some" "Adrenal cortex cells: 330.2;Gonadotrophs: 47.9;Neuroendocrine cells: 49.4;Pancreatic acinar cells: 203.6;Pancreatic islet cells: 89.4;Pericytes: 70.3;Renal collecting duct principal cells: 92.7;Retinal bipolar cells: 80.8" "Cell type enhanced" "Detected in many" "midbrain-derived inhibitory: 48.5;pericyte: 66.0" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 21.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 11.5;thyroid cancer: 10.3" "Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Heart muscle - Macrophages, Pituitary gland - Gonadotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 18: Adrenal cortex cells - Steroidogensis" 5 "unprognostic (1.86e-2)" "unprognostic (4.01e-3)" "unprognostic (1.57e-2)" "unprognostic (1.69e-2)" "unprognostic (2.60e-1)" "potential prognostic favorable (1.28e-5)" "unprognostic (5.89e-3)" "potential prognostic favorable (8.89e-4)" "potential prognostic unfavorable (3.10e-4)" "unprognostic (1.71e-3)" "unprognostic (4.28e-2)" "unprognostic (3.53e-3)" "unprognostic (5.04e-2)" "unprognostic (1.22e-1)" "unprognostic (3.62e-2)" "unprognostic (1.57e-1)" "unprognostic (9.26e-3)" "unprognostic (3.17e-1)" "unprognostic (2.99e-2)" "unprognostic (1.82e-1)" "unprognostic (1.43e-2)" "unprognostic (4.57e-2)" KCNK4 "K2p4.1, TRAAK" ENSG00000182450 "Potassium two pore domain channel subfamily K member 4" Q9NYG8 11 64291302-64300031 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 56 "brain: 13.3" "Cell type enhanced" "Detected in some" "Astrocytes: 3.7;Brain excitatory neurons: 11.2;Brain inhibitory neurons: 7.0;Oligodendrocyte progenitor cells: 2.0;Oligodendrocytes: 1.1;Other brain neurons: 5.7" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 35: Neurons - Synaptic function & neurogenesis" KCNK5 "K2p5.1, TASK-2, TASK2" ENSG00000164626 "Potassium two pore domain channel subfamily K member 5" O95279 6 39188971-39229475 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 33.3;kidney: 34.0" "Cell type enhanced" "Detected in many" "Cholangiocytes: 66.8;Colonocytes: 82.3;Conjunctival goblet cells: 69.9;Enterocytes: 241.0;Proximal tubule cells: 353.7;Salivary basal cells: 80.0;Salivary duct cells: 220.8;Salivary ionocytes: 107.5;Syncytiotrophoblasts: 67.2" "Cell type enhanced" "Detected in some" "fibroblast: 1.5;leukocyte: 1.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Kidney - Proximal tubular cells, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary gland ductal cells, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA059148 Uncertain Approved Nucleoplasm NA NA "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 47: Leukemia - Hemostasis" "Cluster 88: Proximal tubular cells - Transmembrane transport" 24 Nucleoplasm "HPA059148: " "unprognostic (6.36e-2)" "unprognostic (1.60e-1)" "unprognostic (5.09e-2)" "unprognostic (6.22e-2)" "unprognostic (4.83e-2)" "unprognostic (1.65e-1)" "unprognostic (3.95e-3)" "unprognostic (1.40e-2)" "unprognostic (5.17e-3)" "validated prognostic favorable (3.54e-9)" "validated prognostic favorable (1.63e-10)" "unprognostic (1.11e-3)" "unprognostic (2.60e-1)" "unprognostic (8.58e-2)" "unprognostic (3.71e-3)" "unprognostic (2.01e-2)" "unprognostic (6.64e-3)" "unprognostic (1.63e-1)" "unprognostic (1.81e-1)" "unprognostic (3.88e-1)" "potential prognostic unfavorable (6.49e-4)" "unprognostic (1.95e-2)" "unprognostic (1.88e-1)" "unprognostic (4.83e-3)" "unprognostic (8.57e-2)" "unprognostic (6.47e-2)" "unprognostic (2.66e-1)" "unprognostic (1.90e-1)" "unprognostic (7.56e-2)" "unprognostic (2.90e-2)" KCNK6 "K2p6.1, TWIK-2" ENSG00000099337 "Potassium two pore domain channel subfamily K member 6" Q9Y257 19 38319845-38332076 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast lactating cells: 250.5;Decidual stromal cells: 254.3;Esophageal apical cells: 339.2;Esophageal suprabasal cells: 163.9;Platelets: 159.5;Suprabasal keratinocytes: 153.8" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 46.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 26.2" "Group enriched" "Detected in many" 6 "dendritic cells: 11.3;granulocytes: 26.2;monocytes: 7.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB022637, HPA040184" Approved Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 6: Non-specific - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 82: Dendritic cells - Antigen presentation" "Plasma membrane, Cytosol" "Actin filaments" "CAB022637: , HPA040184: " "unprognostic (1.80e-2)" "unprognostic (6.67e-3)" "unprognostic (1.56e-1)" "unprognostic (1.96e-1)" "unprognostic (2.07e-1)" "unprognostic (2.67e-1)" "unprognostic (1.30e-1)" "unprognostic (2.08e-1)" "unprognostic (7.08e-2)" "unprognostic (9.60e-2)" "unprognostic (1.10e-2)" "unprognostic (4.02e-1)" "unprognostic (1.57e-1)" "unprognostic (1.11e-1)" "unprognostic (6.18e-2)" "unprognostic (2.14e-3)" "unprognostic (1.48e-1)" "unprognostic (2.84e-1)" "unprognostic (2.49e-1)" "unprognostic (3.25e-1)" "unprognostic (2.11e-2)" "unprognostic (4.33e-3)" "unprognostic (3.32e-2)" "unprognostic (2.94e-1)" "unprognostic (3.76e-1)" "unprognostic (7.38e-2)" "unprognostic (1.21e-1)" "unprognostic (1.48e-2)" "unprognostic (4.31e-1)" "unprognostic (1.24e-1)" "unprognostic (8.16e-3)" KCNK7 K2p7.1 ENSG00000173338 "Potassium two pore domain channel subfamily K member 7" Q9Y2U2 11 65592836-65595996 "Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 89.2" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 17.7;Esophageal apical cells: 30.4;Esophageal basal cells: 53.0;Esophageal suprabasal cells: 128.9;Suprabasal keratinocytes: 108.0" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 11.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 15 "basophil: 2.1;naive B-cell: 2.2;neutrophil: 1.5" "Group enriched" "Detected in many" 16 "B-cells: 2.2;granulocytes: 2.1" "Cancer enhanced" "Detected in some" "Esophageal cancer: 2.9" "Skin - Keratinocyte (other)" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA077577 Approved "Plasma membrane" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 37: Skin - Keratinization" "Cluster 6: Non-specific - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" "Plasma membrane" "HPA077577: " "unprognostic (4.82e-3)" "unprognostic (1.01e-1)" "unprognostic (8.86e-2)" "unprognostic (3.91e-2)" "unprognostic (1.82e-1)" "unprognostic (1.22e-1)" "unprognostic (4.75e-2)" "unprognostic (9.01e-2)" "unprognostic (3.42e-3)" "unprognostic (2.68e-1)" "unprognostic (5.68e-2)" KCNK9 "K2p9.1, TASK-3, TASK3" ENSG00000169427 "Potassium two pore domain channel subfamily K member 9" Q9NPC2 8 139600838-139704109 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Sodium transport, Transport" "Ion channel, Potassium channel, Sodium channel" "Disease variant, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 7.4" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 53.2;Brain excitatory neurons: 46.0;Corticotrophs: 10.6;Late spermatids: 13.5;Oocytes: 73.7;Other brain neurons: 15.1;Retinal amacrine cells: 26.9;Retinal horizontal cells: 14.0;Thyrotrophs: 30.8;Tuft cells: 11.5" "Cell type enhanced" "Detected in many" "mammillary body: 53.4;upper rhombic lip: 107.4" "Cancer enriched" "Detected in single" 5 "Kidney Renal Clear Cell Carcinoma (TCGA): 2.8" "Region enhanced" "Detected in many" "cerebellum: 19.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 1.1;thyroid cancer: 1.6" "Adrenal gland - Adrenal medulla cells, Pituitary gland - Corticotropes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA075842 Approved "Plasma membrane" NA NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 2: Cerebellar granular cells - Neuronal signaling" "Plasma membrane" "HPA075842: " "unprognostic (2.64e-2)" "unprognostic (5.11e-3)" "unprognostic (1.34e-1)" "unprognostic (2.85e-1)" "unprognostic (1.91e-1)" KCNMA1 "KCa1.1, mSLO1, SLO" ENSG00000156113 "Potassium calcium-activated channel subfamily M alpha 1" Q12791 10 76869601-77638369 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ependymal cells: 1320.9;Kupffer cells: 870.1;Lacrimal acinar cells: 1058.0;Myonuclei: 1079.6;Neutrophils: 829.9;Oligodendrocyte progenitor cells: 1022.8;Retinal bipolar cells: 1789.6;Salivary acinar cells: 1516.9;Salivary ionocytes: 1694.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 2.5;non-classical monocyte: 1.7" "Lineage enhanced" "Detected in single" "monocytes: 2.5" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Heart muscle - Smooth muscle cells, Prostate - Smooth muscle cells, Spleen - Macrophages, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054648 Approved NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 72: Neuronal - Signal transduction" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" 2 "HPA054648: " "unprognostic (3.41e-2)" "unprognostic (8.13e-2)" "unprognostic (2.04e-1)" "unprognostic (4.61e-2)" "unprognostic (1.11e-1)" "unprognostic (2.12e-1)" "unprognostic (1.00e-1)" "unprognostic (1.54e-1)" "unprognostic (4.35e-1)" "unprognostic (4.26e-1)" "potential prognostic favorable (7.57e-5)" "unprognostic (2.38e-2)" "unprognostic (8.94e-2)" "unprognostic (5.27e-1)" "unprognostic (5.40e-3)" "potential prognostic favorable (7.51e-4)" "unprognostic (2.54e-1)" "unprognostic (2.08e-1)" "unprognostic (7.68e-2)" "unprognostic (9.29e-2)" "potential prognostic unfavorable (6.61e-4)" "unprognostic (2.06e-3)" "unprognostic (1.26e-2)" "unprognostic (4.84e-2)" "unprognostic (2.09e-2)" "unprognostic (1.18e-1)" "unprognostic (2.07e-1)" "unprognostic (1.09e-2)" "unprognostic (2.16e-2)" "unprognostic (1.41e-1)" "unprognostic (6.05e-2)" KCNMB1 hslo-beta ENSG00000145936 "Potassium calcium-activated channel subfamily M regulatory beta subunit 1" Q16558 5 170374671-170389634 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 70.3;intestine: 76.1" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 166.2;Decidual stromal cells: 164.1;Leydig cells: 51.3;Microglia: 137.5;Peritubular myoid cells: 343.8;Platelets: 57.5;Salivary myoepithelial cells: 73.7;Smooth muscle cells: 229.0;Vascular smooth muscle cells: 116.3" "Group enriched" "Detected in many" 10 "central nervous system macrophage: 172.4;fibroblast: 70.5;lower rhombic lip: 50.2;vascular associated smooth muscle cell: 78.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "dendritic cells: 5.7;monocytes: 5.9" "Cancer enhanced" "Detected in some" "Leukemia: 3.2" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Adrenal gland - Smooth muscle cells, Colon - Smooth muscle cells, Heart muscle - Smooth muscle cells, Kidney - Fibroblasts, Lung - Smooth muscle cells, Minor Salivary Gland - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Spleen - Smooth muscle cells, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 49: Hindbrain - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 62: Smooth muscle cells - Muscle contraction" "unprognostic (7.51e-2)" "unprognostic (2.06e-2)" "unprognostic (4.05e-1)" "unprognostic (1.33e-2)" "unprognostic (5.84e-2)" "unprognostic (1.49e-1)" "unprognostic (3.31e-2)" "unprognostic (1.18e-3)" "unprognostic (6.82e-2)" "unprognostic (1.72e-1)" "unprognostic (3.68e-2)" "unprognostic (1.15e-1)" "unprognostic (1.21e-1)" "unprognostic (9.98e-2)" "unprognostic (3.90e-2)" "unprognostic (3.33e-2)" "unprognostic (1.66e-1)" "unprognostic (2.54e-1)" "unprognostic (1.54e-1)" "unprognostic (2.30e-1)" "unprognostic (2.50e-1)" "unprognostic (6.67e-2)" "unprognostic (6.44e-3)" "unprognostic (6.66e-2)" "unprognostic (2.13e-1)" "unprognostic (6.79e-2)" "unprognostic (1.04e-1)" "unprognostic (6.85e-2)" "unprognostic (6.51e-3)" KCNMB2 ENSG00000197584 "Potassium calcium-activated channel subfamily M regulatory beta subunit 2" Q9Y691 3 178272932-178844429 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 33.4;fallopian tube: 13.1" "Group enriched" "Detected in many" 5 "Ependymal cells: 1528.9;Oligodendrocyte progenitor cells: 2626.1" "Cell type enhanced" "Detected in all" "oligodendrocyte precursor cell: 3205.3" "Cancer enhanced" "Detected in many" "Pancreatic Adenocarcinoma (TCGA): 5.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 3.9;lymphoma: 7.5" "Adrenal gland - Adrenal medulla cells, Breast - T-cells, Colon - Enteric glia cells, Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Pituitary gland - Somatotropes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" CAB022649 Uncertain NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 51: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 7 "CAB022649: " "unprognostic (1.63e-2)" "unprognostic (2.97e-2)" "unprognostic (1.42e-2)" "unprognostic (1.71e-1)" "unprognostic (7.71e-2)" "unprognostic (8.03e-3)" "unprognostic (1.59e-3)" "unprognostic (3.05e-2)" "unprognostic (2.60e-2)" "unprognostic (9.31e-3)" "unprognostic (7.27e-2)" "unprognostic (2.04e-2)" KCNMB3 "KCNMB2, KCNMBL" ENSG00000171121 "Potassium calcium-activated channel subfamily M regulatory beta subunit 3" Q9NPA1 3 179236691-179267002 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 18.9;Late spermatids: 26.7;Podocytes: 30.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA015665, HPA019185" Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 68: Non-specific - Basic cellular processes" "Cluster 48: Non-specific - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" Nucleoplasm Mitochondria "HPA015665: , HPA019185: " "unprognostic (6.17e-2)" "unprognostic (7.46e-2)" "unprognostic (2.87e-1)" "unprognostic (5.40e-2)" "potential prognostic unfavorable (1.50e-4)" "unprognostic (6.58e-2)" "unprognostic (5.17e-2)" "unprognostic (3.02e-1)" "unprognostic (1.56e-1)" "unprognostic (3.61e-2)" "validated prognostic unfavorable (3.01e-9)" "validated prognostic unfavorable (9.35e-4)" "unprognostic (8.50e-2)" "unprognostic (2.28e-3)" "unprognostic (9.39e-2)" "unprognostic (3.25e-2)" "unprognostic (1.51e-1)" "unprognostic (4.28e-2)" "unprognostic (2.33e-1)" "unprognostic (3.25e-1)" "unprognostic (1.89e-3)" "unprognostic (4.21e-3)" "unprognostic (3.52e-3)" "unprognostic (2.07e-3)" "unprognostic (4.71e-2)" "unprognostic (4.58e-1)" "unprognostic (5.98e-2)" "unprognostic (1.04e-1)" "unprognostic (4.80e-2)" "unprognostic (1.40e-3)" KCNMB4 ENSG00000135643 "Potassium calcium-activated channel subfamily M regulatory beta subunit 4" Q86W47 12 70366290-70434292 "FDA approved drug targets, Predicted membrane proteins" "Ion transport, Transport" "Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 38.1" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 117.9;Ependymal cells: 89.8;Oligodendrocytes: 249.7;Renal collecting duct principal cells: 92.3;Retinal bipolar cells: 100.7;Schwann cells: 642.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 16.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 14.0" "Colon - Enteric glia cells, Liver - Vascular endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072287 Enhanced Approved Approved Cytosol NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 61: Schwann cells & Melanocytes - Mixed function" 2 Cytosol "HPA072287: " "unprognostic (3.20e-1)" "unprognostic (3.72e-1)" "unprognostic (8.17e-2)" "unprognostic (5.30e-3)" "unprognostic (9.16e-2)" "unprognostic (8.08e-2)" "unprognostic (1.04e-1)" "unprognostic (6.73e-3)" "unprognostic (3.54e-2)" "unprognostic (3.78e-2)" "unprognostic (2.83e-1)" "unprognostic (1.38e-2)" "unprognostic (1.39e-1)" "unprognostic (3.83e-2)" "unprognostic (2.68e-1)" "unprognostic (1.48e-1)" "unprognostic (2.45e-3)" "unprognostic (1.13e-1)" "unprognostic (2.03e-1)" "unprognostic (3.38e-1)" "unprognostic (3.67e-3)" "unprognostic (9.38e-3)" "unprognostic (2.32e-3)" "unprognostic (5.83e-2)" "unprognostic (4.06e-2)" "unprognostic (8.39e-2)" "unprognostic (1.39e-1)" "unprognostic (2.84e-2)" "unprognostic (2.16e-1)" KCNN1 "hSK1, KCa2.1" ENSG00000105642 "Potassium calcium-activated channel subfamily N member 1" Q92952 19 17951293-18000085 "FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Transport" "Calmodulin-binding, Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "brain: 23.3" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 12.4;Brain inhibitory neurons: 6.8;cDC: 8.8;Differentiating spermatogonia: 10.6;Endometrial glandular cells: 7.9;Retinal ganglion cells: 15.5;Undifferentiated spermatogonia: 14.2" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 7.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 16.2" "Breast - Breast glandular cells, Colon - Enteric glia cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065938 Approved "Actin filaments,Cytosol" Yes No "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" 1 "Actin filaments, Cytosol" "HPA065938: " "unprognostic (7.84e-2)" "unprognostic (2.36e-1)" "unprognostic (4.00e-1)" "unprognostic (1.00e-2)" "unprognostic (6.57e-3)" "unprognostic (7.98e-2)" "unprognostic (2.80e-1)" "unprognostic (2.47e-1)" "unprognostic (1.62e-1)" "unprognostic (2.95e-1)" KCNN2 "hSK2, KCa2.2" ENSG00000080709 "Potassium calcium-activated channel subfamily N member 2" Q9H2S1 5 114055926-114496500 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Transport" "Calmodulin-binding, Ion channel" "Disease variant, Dystonia, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 19.6;liver: 30.0" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 166.6;Astrocytes: 104.1;Bergmann glia: 497.6;Brain excitatory neurons: 172.6;Cardiomyocytes: 223.1;Ependymal cells: 138.8;Gonadotrophs: 170.4;Lactotrophs: 282.4;Myonuclei: 107.1;Prostatic glandular cells: 174.5;Retinal ganglion cells: 262.7;Thyrotrophs: 165.4" "Cell type enhanced" "Detected in all" "hippocampal CA1-3: 649.6" "Group enriched" "Detected in many" 7 "Glioblastoma Multiforme (TCGA): 10.7;Prostate Adenocarcinoma (TCGA): 37.2;Skin Cutaneous Melanoma (TCGA): 10.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 28.6;skin cancer: 8.3" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Prostate - Prostate glandular cells, Skeletal muscle - Skeletal myocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038221 Uncertain Uncertain "Nucleoplasm,Plasma membrane" NA NA "Cluster 76: Non-specific - Metabolism" "Cluster 29: Forebrain - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 35: Neurons - Synaptic function & neurogenesis" 1 "Nucleoplasm, Plasma membrane" "HPA038221: " "unprognostic (1.94e-1)" "unprognostic (1.98e-3)" "unprognostic (1.37e-1)" "unprognostic (9.59e-2)" "unprognostic (4.45e-2)" "unprognostic (1.82e-1)" "potential prognostic favorable (1.11e-4)" "unprognostic (2.01e-2)" "unprognostic (9.68e-2)" "unprognostic (1.73e-1)" "unprognostic (2.24e-1)" "unprognostic (8.46e-3)" "unprognostic (1.66e-1)" "unprognostic (8.47e-2)" "unprognostic (8.82e-2)" "unprognostic (1.38e-2)" "unprognostic (5.36e-2)" "unprognostic (6.18e-2)" "unprognostic (3.25e-2)" "unprognostic (1.76e-1)" "unprognostic (1.50e-1)" KCNN3 "hSK3, KCa2.3, SKCA3" ENSG00000143603 "Potassium calcium-activated channel subfamily N member 3" Q9UGI6 1 154697455-154870281 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Transport" "Calmodulin-binding, Ion channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 13.8" "Cell type enhanced" "Detected in many" "Astrocytes: 478.6;Bergmann glia: 171.9;Brain inhibitory neurons: 98.4;Distal convoluted tubule cells: 123.5;Ependymal cells: 351.5;Fallopian tube ciliated cells: 119.6;Lymphatic endothelial cells: 114.3;Myosatellite cells: 186.6;Pituitary stem cells: 158.4;Plasma cells: 119.1;Respiratory ciliated cells: 158.7" "Cell type enhanced" "Detected in all" "astrocyte: 617.3;ependymal cell: 350.8" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 10.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 4.7;memory B-cell: 2.6" "Group enriched" "Detected in many" 12 "B-cells: 2.6;granulocytes: 4.7;monocytes: 1.4" "Group enriched" "Detected in some" 5 "lymphoma: 18.8;Myeloma: 37.2" "Adipose subcutaneous - Smooth muscle cells, Colon - Enteric glia cells, Prostate - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA017990, HPA057127" Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 78: Brain - Neuronal signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 28: Astrocytes - Homeostasis & neuron support" "Plasma membrane, Cytosol" "HPA017990: , HPA057127: " "unprognostic (1.57e-1)" "unprognostic (9.17e-2)" "unprognostic (1.04e-1)" "unprognostic (2.40e-1)" "unprognostic (2.06e-1)" "unprognostic (1.29e-1)" "potential prognostic favorable (4.11e-4)" "unprognostic (3.52e-2)" "unprognostic (2.34e-1)" "validated prognostic favorable (1.10e-8)" "validated prognostic favorable (7.85e-6)" "unprognostic (9.14e-2)" "unprognostic (9.51e-2)" "unprognostic (3.92e-2)" "unprognostic (5.45e-2)" "unprognostic (4.40e-3)" "unprognostic (2.64e-3)" "unprognostic (1.49e-2)" "unprognostic (3.86e-2)" "unprognostic (6.89e-2)" "unprognostic (4.23e-2)" "unprognostic (1.37e-1)" "unprognostic (2.47e-2)" KCNN4 "hIKCa1, hKCa4, hSK4, IK, KCa3.1" ENSG00000104783 "Potassium calcium-activated channel subfamily N member 4" O15554 19 43766533-43780976 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Immunity, Ion transport, Transport" "Calmodulin-binding, Ion channel" "Disease variant, FDA approved drug targets, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 119.1" "Cell type enhanced" "Detected in many" "Breast lactating cells: 306.6;Breast secretory cells: 106.7;Cytotrophoblasts: 282.4;Migrating cytotrophoblasts: 159.9;Salivary acinar cells: 90.8;Syncytiotrophoblasts: 994.7" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 11.0;leukocyte: 9.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells (progenitors), Minor Salivary Gland - Minor salivary glandular cells, Skin - Eccrine sweat gland cells, Spleen - B-cells (Spleen), Stomach - Gastric mucous cells" "Region enhanced" "Detected in single" "olfactory bulb: 1.9" "Not detected" "Not detected" "HPA013367, HPA053841, HPA059622" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 82: Salivary gland - Secretion" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 69: Skin cancer - ECM organization" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 39 "Plasma membrane, Cytosol" "HPA013367: , HPA053841: , HPA059622: " "unprognostic (4.27e-3)" "unprognostic (4.76e-3)" "unprognostic (5.18e-2)" "unprognostic (1.70e-3)" "unprognostic (7.19e-2)" "unprognostic (2.16e-1)" "unprognostic (3.79e-3)" "unprognostic (2.44e-1)" "unprognostic (1.30e-2)" "unprognostic (9.87e-2)" "validated prognostic unfavorable (1.54e-5)" "validated prognostic unfavorable (1.44e-4)" "unprognostic (1.87e-3)" "unprognostic (2.28e-1)" "unprognostic (1.72e-1)" "unprognostic (4.97e-3)" "unprognostic (4.10e-2)" "unprognostic (1.28e-2)" "unprognostic (3.02e-2)" "unprognostic (9.67e-2)" "unprognostic (3.70e-1)" "potential prognostic unfavorable (9.06e-5)" "unprognostic (4.22e-1)" "unprognostic (8.41e-3)" "unprognostic (1.72e-1)" "unprognostic (2.20e-1)" "unprognostic (4.69e-3)" "unprognostic (3.00e-2)" "unprognostic (2.42e-1)" "unprognostic (1.29e-1)" "unprognostic (4.47e-3)" KCNQ1 "JLNS1, KCNA8, KCNA9, Kv7.1, KVLQT1, LQT, LQT1" ENSG00000053918 "Potassium voltage-gated channel subfamily Q member 1" P51787 11 2444684-2849105 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Calmodulin-binding, Ion channel, Potassium channel, Voltage-gated channel" "Atrial fibrillation, Deafness, Diabetes mellitus, Disease variant, FDA approved drug targets, Long QT syndrome, Short QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 196.1;stomach 1: 96.3" "Group enriched" "Detected in many" 4 "Adrenal cortex cells: 1118.5;Epicardial cells: 2417.4" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 392.3" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 119.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "colorectal cancer: 32.2;Gastric cancer: 20.3" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Heart muscle - Cardiomyocytes, Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Macrophages, Spleen - Macrophages, Stomach - Parietal cells, Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA011306, HPA048553, HPA071107" Enhanced Enhanced "Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 9 "Endoplasmic reticulum" "Plasma membrane, Cytosol" "HPA011306: , HPA048553: , HPA071107: " "unprognostic (1.69e-3)" "unprognostic (3.84e-1)" "unprognostic (2.52e-1)" "unprognostic (1.35e-1)" "unprognostic (1.75e-1)" "unprognostic (4.83e-2)" "unprognostic (2.19e-1)" "unprognostic (1.57e-1)" "unprognostic (1.59e-1)" "unprognostic (9.76e-2)" "potential prognostic favorable (9.37e-5)" "unprognostic (1.16e-3)" "unprognostic (9.03e-2)" "unprognostic (1.29e-1)" "unprognostic (1.49e-1)" "unprognostic (3.50e-3)" "unprognostic (3.22e-2)" "unprognostic (2.05e-3)" "unprognostic (4.64e-1)" "unprognostic (6.94e-2)" "unprognostic (1.78e-1)" "unprognostic (6.88e-2)" "unprognostic (9.32e-2)" "unprognostic (1.53e-1)" "unprognostic (1.22e-1)" "unprognostic (7.87e-3)" "unprognostic (8.78e-3)" "unprognostic (4.42e-3)" "unprognostic (1.75e-2)" "unprognostic (1.29e-1)" "unprognostic (4.41e-2)" KCNQ2 "BFNC, EBN, EBN1, ENB1, HNSPC, KCNA11, Kv7.2" ENSG00000075043 "Potassium voltage-gated channel subfamily Q member 2" O43526 20 63400208-63472677 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "brain: 135.5" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 74.5;Astrocytes: 20.9;Bergmann glia: 22.5;Brain excitatory neurons: 91.7;Brain inhibitory neurons: 78.8;Oligodendrocyte progenitor cells: 100.2;Other brain neurons: 50.2;Undifferentiated spermatogonia: 33.2" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in some" 10 "Glioblastoma Multiforme (TCGA): 38.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 18.5;Neuroblastoma: 51.2" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Beta cells, Pituitary gland - Thyrotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016642, HPA057112" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 2 "Endoplasmic reticulum" "HPA016642: , HPA057112: " "unprognostic (1.34e-1)" "unprognostic (1.51e-2)" "unprognostic (5.51e-2)" "unprognostic (2.21e-1)" "unprognostic (3.47e-2)" KCNQ3 "EBN2, Kv7.3" ENSG00000184156 "Potassium voltage-gated channel subfamily Q member 3" O43525 8 132120859-132481095 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 15.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 353.1;Alveolar cells type 2: 266.2;Brain excitatory neurons: 414.8;Brain inhibitory neurons: 571.3;Gonadotrophs: 292.5;Microglia: 2144.3;Other brain neurons: 512.5;Pancreatic acinar cells: 606.5;Transitional alveolar cells: 210.0" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 2585.5" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 5.0;Thyroid Carcinoma (TCGA): 4.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 1 "unprognostic (2.08e-1)" "unprognostic (1.12e-3)" "unprognostic (3.22e-1)" "unprognostic (6.14e-2)" "unprognostic (2.55e-2)" "unprognostic (1.38e-1)" "unprognostic (1.94e-1)" "unprognostic (5.54e-3)" "unprognostic (8.75e-3)" "unprognostic (1.34e-1)" "unprognostic (1.05e-1)" "unprognostic (1.89e-2)" "unprognostic (9.82e-2)" KCNQ4 "DFNA2, Kv7.4" ENSG00000117013 "Potassium voltage-gated channel subfamily Q member 4" P56696 1 40783787-40840452 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Hearing, Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 3.7" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 31.0;Myonuclei: 30.9;Pituitary stem cells: 21.6;Retinal pigment epithelial cells: 98.0;Tuft cells: 80.7;Vascular smooth muscle cells: 15.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA018305 Uncertain NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 23: Choroid plexus - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" "HPA018305: " "unprognostic (3.66e-2)" "unprognostic (3.11e-1)" "unprognostic (1.87e-1)" "unprognostic (1.55e-1)" "unprognostic (1.88e-1)" "unprognostic (4.57e-2)" "unprognostic (2.22e-2)" "unprognostic (1.23e-1)" KCNQ5 Kv7.5 ENSG00000185760 "Potassium voltage-gated channel subfamily Q member 5" Q9NR82 6 72621792-73198853 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 4.0;brain: 12.5;skeletal muscle: 15.2;thyroid gland: 4.1;tongue: 11.0" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 531.8;B-cells: 506.7;Brain excitatory neurons: 956.2;Brain inhibitory neurons: 1755.9;Hematopoietic stem cells: 576.4;Innate lymphoid cells: 544.6;Medullary thymic epithelial cells: 645.7;Megakaryocyte progenitors: 626.4;Megakaryocyte-Erythroid progenitors: 1102.3;Myonuclei: 2577.1;Myosatellite cells: 503.5;Neutrophil progenitors: 822.6;Thymic myoid cells: 742.4" "Cell type enhanced" "Detected in all" "lower rhombic lip: 5906.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal medulla cells, Breast - Breast myoepithelial cells, Colon - Colon enteroendocrine cells, Spleen - B-cells (Spleen), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA016655 Approved Uncertain "Cytoplasmic bodies" NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 24: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" "Cytoplasmic bodies" "HPA016655: " "unprognostic (1.25e-1)" "unprognostic (1.60e-1)" "unprognostic (1.09e-1)" "unprognostic (1.22e-1)" "unprognostic (1.55e-2)" "unprognostic (2.17e-3)" "unprognostic (2.05e-2)" "potential prognostic unfavorable (2.65e-5)" "unprognostic (4.10e-3)" "unprognostic (2.60e-1)" "unprognostic (1.15e-2)" "unprognostic (3.45e-2)" KCNRG ENSG00000198553 "Potassium channel regulator" Q8N5I3 13 50015254-50020922 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "fallopian tube: 33.6" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 51.8;Epicardial cells: 18.2;Epididymal efferent duct ciliated cells: 30.6;Fallopian tube ciliated cells: 110.8;Late primary spermatocytes: 29.0;Late spermatids: 20.3;Respiratory ciliated cells: 99.9" "Cell type enriched" "Detected in single" 6 "ependymal cell: 6.2" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 4.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA001027 Uncertain "Golgi apparatus,Vesicles,Basal body" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 6: Non-specific - Immune response" "Cluster 60: Prostate cancer - Unknown function" "Cluster 107: Ciliated cells - Cilia assembly & function" 2 "Golgi apparatus, Vesicles" "Basal body" "HPA001027: " "unprognostic (2.12e-1)" "unprognostic (3.18e-1)" "unprognostic (2.26e-1)" "unprognostic (1.04e-1)" "unprognostic (5.53e-3)" "unprognostic (2.13e-2)" "unprognostic (2.54e-1)" "unprognostic (4.49e-2)" "unprognostic (1.63e-2)" "unprognostic (1.20e-2)" "unprognostic (2.03e-2)" "unprognostic (1.61e-1)" "unprognostic (1.85e-1)" KCNS1 Kv9.1 ENSG00000124134 "Potassium voltage-gated channel modifier subfamily S member 1" Q96KK3 20 45091214-45101127 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "brain: 24.0" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 2.7;Brain excitatory neurons: 1.5;Breast secretory cells: 1.1;Cholangiocytes: 6.7;Differentiating spermatogonia: 1.4;Mesothelial cells: 1.0;Salivary acinar cells: 1.2;Salivary myoepithelial cells: 1.3" "Cell type enhanced" "Detected in some" "upper-layer intratelencephalic: 6.1" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 9.5" "Region enhanced" "Detected in all" "cerebral cortex: 58.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "cervical cancer: 11.4;thyroid cancer: 4.0" "Colon - Enteric glia cells, Pituitary gland - Gonadotropes, Skin - Keratinocyte (other), Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA043351 Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 35: Neurons - Synaptic function & neurogenesis" "Vesicles, Plasma membrane" Nucleoplasm "HPA043351: " "unprognostic (5.30e-2)" "unprognostic (5.09e-3)" "unprognostic (6.35e-3)" "unprognostic (2.08e-3)" "unprognostic (1.14e-2)" "potential prognostic unfavorable (2.09e-8)" "unprognostic (2.30e-3)" "unprognostic (1.21e-3)" "potential prognostic unfavorable (3.45e-4)" "unprognostic (1.59e-1)" "unprognostic (5.57e-2)" "unprognostic (2.90e-1)" "unprognostic (2.09e-1)" "unprognostic (3.33e-1)" KCNS2 Kv9.2 ENSG00000156486 "Potassium voltage-gated channel modifier subfamily S member 2" Q9ULS6 8 98426958-98432853 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.0" "Cell type enhanced" "Detected in some" "Adipocytes: 1.2;Brain excitatory neurons: 3.6;Brain inhibitory neurons: 4.0;Decidual stromal cells: 8.5;Endometrial stromal cells: 2.6;Epicardial cells: 2.3;Fibroblasts: 1.2;Other brain neurons: 2.5;Retinal amacrine cells: 4.1" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Kidney cancer: 1.3" "Adrenal gland - Fibroblasts, Breast - Endothelial cells, Heart muscle - Macrophages, Pituitary gland - Somatotropes, Spleen - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051417 Uncertain NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 35: Neurons - Synaptic function & neurogenesis" 3 "HPA051417: " "unprognostic (2.82e-1)" KCNS3 Kv9.3 ENSG00000170745 "Potassium voltage-gated channel modifier subfamily S member 3" Q9BQ31 2 17877847-18361616 "Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 80.6;tongue: 42.5" "Cell type enhanced" "Detected in many" "Bergmann glia: 51.1;Breast lactating cells: 50.3;Fibro-adipogenic progenitors: 63.7;Myonuclei: 160.7;Myosatellite cells: 57.5;Oligodendrocyte progenitor cells: 52.4;Retinal pigment epithelial cells: 63.9" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 165.1;MGE interneuron: 103.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Skeletal myocytes, Spleen - Fibroblasts_1, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014864 Approved Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" Cytosol "Golgi apparatus, Plasma membrane" "HPA014864: " "potential prognostic favorable (6.40e-4)" "unprognostic (1.18e-2)" "unprognostic (3.18e-1)" "unprognostic (8.01e-2)" "unprognostic (3.59e-1)" "unprognostic (8.00e-3)" "unprognostic (3.61e-1)" "unprognostic (2.67e-2)" "unprognostic (1.78e-2)" "unprognostic (1.59e-2)" "unprognostic (2.91e-1)" "unprognostic (1.17e-1)" "unprognostic (1.91e-2)" "unprognostic (2.31e-1)" "unprognostic (4.21e-2)" "unprognostic (3.73e-1)" "unprognostic (1.26e-1)" "unprognostic (3.12e-2)" "unprognostic (1.16e-1)" "unprognostic (1.51e-1)" "unprognostic (1.92e-1)" "unprognostic (4.80e-2)" "unprognostic (7.69e-2)" "unprognostic (1.95e-1)" "unprognostic (3.63e-1)" "unprognostic (6.31e-2)" "unprognostic (2.47e-2)" "unprognostic (8.32e-3)" "unprognostic (2.78e-1)" "unprognostic (2.52e-1)" "unprognostic (4.17e-2)" KCNT1 "KCa4.1, KIAA1422, SLACK, Slo2.2" ENSG00000107147 "Potassium sodium-activated channel subfamily T member 1" Q5JUK3 9 135702185-135795508 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 53.2;lymphoid tissue: 14.7;skeletal muscle: 12.6" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 49.2;Brain inhibitory neurons: 66.8;Gonadotrophs: 25.6;Lactotrophs: 14.5;Myonuclei: 22.6;Oocytes: 18.4;Other brain neurons: 23.6;Retinal ganglion cells: 11.6" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in single" "Ovary Serous Cystadenocarcinoma (TCGA): 1.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "Neuroblastoma: 5.6" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Cardiomyocytes, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 56.2" "HPA059880, HPA060577" Uncertain Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 53: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" "Plasma membrane" Nucleoplasm "HPA059880: , HPA060577: " "unprognostic (1.44e-1)" "potential prognostic unfavorable (1.39e-4)" "unprognostic (1.99e-2)" KCNT2 "KCa4.2, SLICK, SLO2.1" ENSG00000162687 "Potassium sodium-activated channel subfamily T member 2" Q6UVM3 1 196225779-196609225 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "ovary: 3.5" "Cell type enhanced" "Detected in many" "Bergmann glia: 582.7;Brain inhibitory neurons: 211.0;Epicardial cells: 1150.7;Fibro-adipogenic progenitors: 268.3;Gonadotrophs: 602.7;Lactotrophs: 322.9;Mesothelial cells: 684.0;Oligodendrocyte progenitor cells: 388.3;Other brain neurons: 289.2;Thyrotrophs: 492.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Kidney Renal Papillary Cell Carcinoma (TCGA): 1.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 4.0" "Adipose visceral - Mesothelial cells, Adrenal gland - Fibroblasts, Prostate - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051218 Uncertain Approved Vesicles NA NA "Cluster 75: Ovary - Mixed function" "Cluster 14: Neurons - Synaptic function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" Vesicles "HPA051218: " "unprognostic (3.32e-1)" "unprognostic (6.79e-2)" "potential prognostic favorable (2.67e-4)" "unprognostic (1.90e-1)" "unprognostic (8.72e-2)" "unprognostic (9.08e-2)" "unprognostic (1.37e-2)" KCNU1 "KCa5.1, Kcnma3, KCNMC1, Slo3" ENSG00000215262 "Potassium calcium-activated channel subfamily U member 1" A8MYU2 8 36784324-36936125 "Human disease related genes, Predicted membrane proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 18 "testis: 6.5" "Group enriched" "Detected in some" 9 "Adipocytes: 106.5;Early spermatids: 112.2;Late primary spermatocytes: 65.2;Late spermatids: 32.0" "Cell type enhanced" "Detected in some" "astrocyte: 5.1;choroid plexus epithelial cell: 4.5" "Cancer enhanced" "Detected in single" "Liver Hepatocellular Carcinoma (TCGA): 1.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA063317 Approved "Plasma membrane,Principal piece" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 7: Liver cancer - Metabolism" "Cluster 89: Adipocytes - Lipid metabolism" "Plasma membrane, Principal piece" "HPA063317: " "unprognostic (2.99e-2)" "unprognostic (4.25e-2)" "unprognostic (1.62e-2)" KCNV1 Kv8.1 ENSG00000164794 "Potassium voltage-gated channel modifier subfamily V member 1" Q6PIU1 8 109963636-109975771 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 26 "brain: 12.7" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 12.9;Brain inhibitory neurons: 3.3;Enteric stem cells: 3.7;Enteric transient amplifying cells: 1.7;Goblet cells: 2.2;Lactotrophs: 2.1;Neuroendocrine cells: 5.6;Other brain neurons: 1.9;Paneth cells: 7.7" "Cell type enhanced" "Detected in many" "deep-layer intratelencephalic: 42.7;upper-layer intratelencephalic: 35.0" "Cancer enriched" "Detected in single" 4 "Kidney Renal Papillary Cell Carcinoma (TCGA): 2.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 2.5" "Pituitary gland - Lactotropes" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 48.0" HPA067233 Supported "Plasma membrane,Cytokinetic bridge" Yes NA "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 35: Neurons - Synaptic function & neurogenesis" "Plasma membrane, Cytokinetic bridge" "HPA067233: " "unprognostic (4.31e-3)" "unprognostic (7.87e-2)" "unprognostic (1.51e-2)" "unprognostic (2.90e-1)" "unprognostic (1.67e-1)" KCNV2 Kv8.2 ENSG00000168263 "Potassium voltage-gated channel modifier subfamily V member 2" Q8TDN2 9 2717510-2730037 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 59 "retina: 268.2" "Group enriched" "Detected in many" 5 "Cone photoreceptor cells: 732.8;Rod photoreceptor cells: 532.0" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in single" 90 "Testicular Germ Cell Tumor (TCGA): 9.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA031131 Enhanced NA NA "Cluster 42: Retina - Visual perception" "Cluster 33: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 79: Photoreceptor cells - Phototransduction" 2 "HPA031131: " "unprognostic (4.00e-1)" KCP "CRIM2, FLJ33365, NET67" ENSG00000135253 "Kielin cysteine rich BMP regulator" Q6ZWJ8 7 128862042-128910719 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "kidney: 18.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 140.4;Enterocytes: 65.9;Epicardial cells: 86.4;Late spermatids: 52.8;Loop of henle epithelial cells: 105.1;Papillary tip epithelial cells: 101.0;Proximal tubule cells: 54.3;Renal collecting duct principal cells: 149.0;Renal connecting tubule cells: 60.5" "Cell type enriched" "Detected in many" 4 "upper rhombic lip: 63.7" "Cancer enriched" "Detected in many" 5 "Kidney Renal Papillary Cell Carcinoma (TCGA): 19.0" "Region enriched" "Detected in single" 4 "cerebellum: 3.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Gallbladder cancer: 13.0;Kidney cancer: 8.2" "Skin - Fibroblasts_1, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" "No annotated function" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 35: Non-specific - DNA binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" "unprognostic (1.22e-2)" "unprognostic (2.59e-1)" "unprognostic (9.83e-2)" "unprognostic (2.09e-2)" "unprognostic (1.74e-1)" "unprognostic (2.23e-1)" "unprognostic (9.01e-3)" "unprognostic (2.22e-1)" "unprognostic (8.35e-2)" "unprognostic (2.10e-2)" "unprognostic (2.03e-1)" "unprognostic (4.17e-3)" "unprognostic (1.93e-3)" "unprognostic (1.55e-1)" "unprognostic (1.72e-1)" "unprognostic (1.38e-1)" "unprognostic (1.10e-1)" KCTD1 C18orf5 ENSG00000134504 "Potassium channel tetramerization domain containing 1" Q719H9 18 26454910-26657401 "Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 559.6;Ependymal cells: 301.5;Loop of henle epithelial cells: 309.6;Pituicytes/FSCs: 494.4;Pituitary stem cells: 322.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057808, HPA062486" Approved "Nucleoplasm,Nucleoli,Cytokinetic bridge,Centriolar satellite" Yes NA "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 23 Nucleoplasm "Nucleoli, Cytokinetic bridge, Centriolar satellite" "HPA057808: , HPA062486: " "unprognostic (1.14e-2)" "unprognostic (5.60e-2)" "unprognostic (1.55e-1)" "unprognostic (1.27e-1)" "unprognostic (1.37e-1)" "unprognostic (9.82e-2)" "unprognostic (5.39e-3)" "unprognostic (1.66e-2)" "unprognostic (1.40e-1)" "unprognostic (2.39e-1)" "unprognostic (9.69e-2)" "unprognostic (1.65e-3)" "potential prognostic favorable (6.32e-4)" "unprognostic (3.25e-3)" "unprognostic (1.13e-1)" "unprognostic (1.16e-3)" "unprognostic (2.85e-1)" "unprognostic (8.69e-3)" "unprognostic (4.64e-3)" "unprognostic (1.86e-2)" "unprognostic (2.67e-1)" "unprognostic (1.18e-2)" "unprognostic (1.57e-1)" "unprognostic (1.08e-1)" "unprognostic (5.44e-2)" "unprognostic (2.74e-2)" "unprognostic (1.57e-1)" "unprognostic (2.53e-2)" "unprognostic (1.24e-2)" "unprognostic (1.00e-1)" "unprognostic (9.50e-2)" KCTD10 "BTBD28, MSTP028" ENSG00000110906 "Potassium channel tetramerization domain containing 10" Q9H3F6 12 109448655-109477359 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 88.3;Platelets: 94.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014273 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 44: Non-specific - Mixed function" "Cluster 61: BICR 18 - Protein kinases" "Cluster 62: Smooth muscle cells - Muscle contraction" 32 Nucleoplasm Cytosol "HPA014273: " "unprognostic (3.14e-1)" "unprognostic (1.92e-2)" "unprognostic (1.86e-1)" "potential prognostic unfavorable (6.39e-4)" "unprognostic (3.32e-1)" "unprognostic (3.43e-1)" "unprognostic (3.45e-2)" "unprognostic (4.63e-1)" "unprognostic (1.27e-1)" "unprognostic (4.24e-2)" "potential prognostic favorable (1.94e-4)" "unprognostic (5.19e-2)" "unprognostic (2.60e-1)" "potential prognostic unfavorable (6.74e-4)" "unprognostic (8.52e-2)" "unprognostic (3.51e-1)" "unprognostic (2.11e-3)" "unprognostic (7.85e-3)" "unprognostic (3.22e-3)" "unprognostic (6.64e-2)" "unprognostic (1.54e-3)" "unprognostic (2.19e-1)" "unprognostic (6.27e-2)" "unprognostic (3.81e-1)" "unprognostic (1.93e-1)" "unprognostic (4.06e-2)" "unprognostic (1.65e-1)" "unprognostic (1.05e-1)" "unprognostic (3.12e-1)" "unprognostic (2.95e-1)" "unprognostic (1.91e-1)" KCTD11 "C17orf36, KCASH1, REN" ENSG00000213859 "Potassium channel tetramerization domain containing 11" Q693B1 17 7351889-7354944 "Predicted intracellular proteins" "Cell cycle, Growth regulation, Ubl conjugation pathway" "Developmental protein, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 2.0;Bergmann glia: 1.9;Choroid plexus epithelial cells: 2.3;Ependymal cells: 3.8;Loop of henle epithelial cells: 1.5;Microglia: 2.6;Oligodendrocytes: 2.2;Other brain neurons: 1.2;Papillary tip epithelial cells: 5.3;Podocytes: 4.9;Proximal tubule cells: 1.3;Renal collecting duct intercalated cells: 1.0;Renal collecting duct principal cells: 1.4;Renal connecting tubule cells: 1.2" "Cell type enhanced" "Detected in many" "pericyte: 5.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 9.5" "Group enriched" "Detected in all" 4 "granulocytes: 9.5;monocytes: 3.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052035 Approved Approved Nucleoplasm NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 25: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 98: Neurons - Neurotransmission & signaling" 4 Nucleoplasm "HPA052035: " "unprognostic (3.71e-1)" "unprognostic (1.80e-1)" "unprognostic (1.18e-1)" "unprognostic (1.53e-2)" "unprognostic (1.30e-1)" "unprognostic (1.45e-3)" "unprognostic (1.44e-2)" "potential prognostic unfavorable (5.31e-4)" "unprognostic (1.74e-2)" "unprognostic (6.19e-3)" "potential prognostic favorable (7.63e-4)" "unprognostic (1.32e-1)" "unprognostic (5.48e-3)" "unprognostic (1.56e-2)" "unprognostic (3.06e-3)" "unprognostic (1.35e-2)" "unprognostic (2.52e-3)" "unprognostic (1.17e-2)" "unprognostic (1.90e-2)" "unprognostic (2.09e-3)" "unprognostic (1.41e-2)" "unprognostic (3.80e-2)" "unprognostic (1.58e-1)" "unprognostic (1.40e-1)" "unprognostic (2.12e-1)" "unprognostic (1.30e-1)" "unprognostic (1.36e-1)" "unprognostic (2.60e-1)" "unprognostic (1.53e-1)" "unprognostic (1.61e-2)" "unprognostic (4.72e-2)" KCTD12 "C13orf2, KIAA1778, PFET1" ENSG00000178695 "Potassium channel tetramerization domain containing 12" Q96CX2 13 76880175-76886405 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 384.0;Kupffer cells: 523.7;Lymphatic endothelial cells: 207.1;Macrophages: 300.8;Monocyte progenitors: 265.9;monocytes: 392.7;Neuroendocrine cells: 405.6;Pancreatic islet cells: 170.3;Respiratory ciliated cells: 213.0;Vascular endothelial cells: 284.3" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 178.8;endothelial cell: 143.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 3.9;myeloid DC: 3.7" "Group enriched" "Detected in many" 17 "dendritic cells: 3.7;granulocytes: 1.0;monocytes: 3.9" "Cancer enhanced" "Detected in all" "Neuroblastoma: 43.5" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Kidney - Fibroblasts, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056987, HPA077376" Supported Uncertain Mitochondria NA NA 4700000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 44: Non-specific - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 8 Mitochondria "HPA056987: , HPA077376: " "unprognostic (1.32e-2)" "unprognostic (7.19e-2)" "unprognostic (2.06e-1)" "unprognostic (5.96e-3)" "unprognostic (2.52e-1)" "unprognostic (1.28e-1)" "unprognostic (1.85e-1)" "unprognostic (1.88e-2)" "unprognostic (5.25e-2)" "unprognostic (2.96e-1)" "potential prognostic favorable (5.53e-6)" "unprognostic (1.78e-1)" "unprognostic (1.24e-1)" "unprognostic (7.50e-2)" "unprognostic (8.34e-2)" "unprognostic (1.62e-3)" "unprognostic (1.60e-2)" "unprognostic (3.15e-1)" "unprognostic (1.38e-1)" "unprognostic (3.67e-2)" "unprognostic (3.34e-2)" "unprognostic (1.31e-2)" "unprognostic (7.64e-2)" "unprognostic (8.51e-2)" "unprognostic (1.55e-1)" "unprognostic (1.33e-1)" "unprognostic (1.75e-2)" "unprognostic (2.70e-3)" "unprognostic (6.13e-2)" "unprognostic (1.27e-1)" "unprognostic (4.23e-2)" KCTD13 "FKSG86, PDIP1, POLDIP1" ENSG00000174943 "Potassium channel tetramerization domain containing 13" Q8WZ19 16 29905012-29926236 "Disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Autism, Autism spectrum disorder, Disease variant, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 64.5;testis: 61.7" "Group enriched" "Detected in many" 4 "Epicardial cells: 270.6;Sertoli cells: 133.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043524 Enhanced Supported "Nucleoplasm,Nuclear bodies" No No "Cluster 33: Non-specific - ATP binding" "Cluster 78: Brain - Neuronal signaling" "Cluster 29: Forebrain - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 43 "Nucleoplasm, Nuclear bodies" "HPA043524: " "unprognostic (1.32e-1)" "unprognostic (6.30e-3)" "unprognostic (2.02e-2)" "potential prognostic favorable (2.34e-5)" "unprognostic (1.34e-1)" "unprognostic (1.25e-1)" "unprognostic (2.77e-1)" "unprognostic (2.06e-3)" "unprognostic (1.36e-1)" "unprognostic (1.41e-2)" "unprognostic (2.30e-2)" "unprognostic (4.32e-2)" "unprognostic (5.37e-3)" "unprognostic (8.89e-2)" "unprognostic (3.12e-2)" "unprognostic (6.70e-2)" "unprognostic (2.20e-1)" "unprognostic (3.58e-2)" "unprognostic (1.98e-1)" "unprognostic (2.71e-2)" "unprognostic (4.49e-2)" "unprognostic (2.43e-2)" "unprognostic (5.37e-3)" "unprognostic (1.86e-2)" "unprognostic (3.07e-1)" "unprognostic (6.15e-2)" "unprognostic (3.09e-3)" "unprognostic (2.26e-1)" "unprognostic (1.04e-1)" "unprognostic (6.86e-2)" "unprognostic (2.92e-2)" KCTD14 MGC2376 ENSG00000151364 "Potassium channel tetramerization domain containing 14" Q9BQ13 11 78015715-78046191 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 20.5;Breast lactating cells: 50.4;Breast secretory cells: 13.9;Epididymal efferent duct absorptive cells: 21.4;Epididymal principal cells: 25.5;Foveolar cells: 26.8;Goblet cells: 19.9;Pancreatic acinar cells: 22.1;Submucosal glandular cells: 14.0" "Cell type enhanced" "Detected in some" "oligodendrocyte precursor cell: 1.9;upper rhombic lip: 1.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Skin - Eccrine sweat gland cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041118, HPA042181" Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 70: Non-specific - Protein processing" "Cluster 35: Non-specific - DNA binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 70: Intestinal goblet cells - Mucin production" 13 Nucleoplasm "Vesicles, Cytosol" "HPA041118: , HPA042181: " "unprognostic (1.56e-1)" "unprognostic (2.33e-2)" "unprognostic (1.88e-1)" "unprognostic (1.89e-2)" "unprognostic (5.04e-2)" "unprognostic (2.10e-1)" "unprognostic (3.86e-2)" "unprognostic (1.97e-3)" "unprognostic (1.71e-2)" "unprognostic (3.74e-2)" "potential prognostic favorable (1.75e-9)" "unprognostic (9.44e-2)" "unprognostic (9.27e-3)" "unprognostic (1.41e-3)" "unprognostic (1.25e-1)" "unprognostic (6.72e-2)" "unprognostic (5.33e-2)" "unprognostic (4.71e-2)" "unprognostic (1.27e-1)" "unprognostic (3.92e-3)" "unprognostic (2.43e-1)" "potential prognostic unfavorable (1.53e-4)" "unprognostic (2.03e-1)" "unprognostic (2.94e-1)" "unprognostic (2.17e-3)" "unprognostic (1.81e-1)" "potential prognostic unfavorable (1.66e-4)" "unprognostic (2.27e-2)" "unprognostic (9.80e-2)" "potential prognostic favorable (8.01e-4)" "unprognostic (6.62e-2)" KCTD15 MGC25497 ENSG00000153885 "Potassium channel tetramerization domain containing 15" Q96SI1 19 33795933-33815763 "Predicted intracellular proteins" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 75.2" "Cell type enhanced" "Detected in many" "Astrocytes: 68.4;Bergmann glia: 38.7;Cone photoreceptor cells: 29.0;Ependymal cells: 26.5;Rod photoreceptor cells: 25.9;Smooth muscle cells: 29.6" "Cell type enhanced" "Detected in many" "astrocyte: 73.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 1.7;eosinophil: 6.1;intermediate monocyte: 3.3;myeloid DC: 2.5;non-classical monocyte: 5.0" "Group enriched" "Detected in many" 6 "dendritic cells: 2.5;granulocytes: 6.1;monocytes: 5.0" "Low cancer specificity" "Detected in all" "Adrenal gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042522 Approved Nucleoplasm,Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 58: Skin - Keratinization" "Cluster 39: Astrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 28: Astrocytes - Homeostasis & neuron support" 10 Nucleoplasm Cytosol "HPA042522: " "unprognostic (5.86e-2)" "unprognostic (6.71e-3)" "unprognostic (4.14e-1)" "unprognostic (1.85e-3)" "unprognostic (4.57e-2)" "unprognostic (2.70e-2)" "unprognostic (1.07e-1)" "unprognostic (2.98e-2)" "unprognostic (6.63e-2)" "unprognostic (4.56e-3)" "unprognostic (2.77e-2)" "unprognostic (1.46e-1)" "unprognostic (1.04e-3)" "unprognostic (2.51e-2)" "unprognostic (7.90e-2)" "unprognostic (4.88e-3)" "unprognostic (1.49e-2)" "unprognostic (1.53e-1)" "unprognostic (1.55e-2)" "unprognostic (1.40e-1)" "unprognostic (1.42e-1)" "unprognostic (3.70e-1)" "unprognostic (1.54e-2)" "unprognostic (6.18e-2)" "unprognostic (6.77e-2)" "unprognostic (1.92e-1)" "unprognostic (1.78e-2)" "unprognostic (2.88e-1)" "unprognostic (8.38e-2)" "unprognostic (1.10e-1)" "unprognostic (2.02e-1)" KCTD16 KIAA1317 ENSG00000183775 "Potassium channel tetramerization domain containing 16" Q68DU8 5 144170873-144485686 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 7.1;retina: 1.8" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 436.1;Brain excitatory neurons: 645.1;Brain inhibitory neurons: 589.1;Ependymal cells: 152.0;Loop of henle epithelial cells: 202.6;Oligodendrocyte progenitor cells: 491.9;Other brain neurons: 184.1;Proximal tubule cells: 141.4;Retinal bipolar cells: 121.8;Somatotrophs: 170.8;Thyrotrophs: 127.9" "Cell type enhanced" "Detected in all" "hippocampal dentate gyrus: 2240.0" "Cancer enhanced" "Detected in single" "Kidney Renal Papillary Cell Carcinoma (TCGA): 1.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Neuroblastoma: 3.6" "Adrenal gland - Adrenal medulla cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA044590, HPA050154" Approved Approved "Vesicles,Centrosome,Mid piece,Principal piece,End piece" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 35: Neurons - Synaptic function & neurogenesis" 3 Centrosome "Vesicles, Mid piece, Principal piece, End piece" "HPA044590: , HPA050154: " "unprognostic (8.34e-3)" "unprognostic (3.48e-3)" "potential prognostic favorable (6.19e-7)" KCTD17 FLJ12242 ENSG00000100379 "Potassium channel tetramerization domain containing 17" Q8N5Z5 22 37051739-37063390 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Ubl conjugation pathway" "Disease variant, Dystonia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 147.4" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 27.6;Brain inhibitory neurons: 48.5;Corticotrophs: 34.4;Ependymal cells: 52.2;Late primary spermatocytes: 42.5;Late spermatids: 36.9;Lymphatic endothelial cells: 31.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Pituitary gland - Corticotropes, Skin - Keratinocyte (granular), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018459 Uncertain NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 35: Neurons - Synaptic function & neurogenesis" 39 "HPA018459: " "unprognostic (1.17e-1)" "unprognostic (2.23e-2)" "unprognostic (2.04e-1)" "unprognostic (8.81e-2)" "unprognostic (2.03e-1)" "unprognostic (5.48e-2)" "unprognostic (9.40e-2)" "unprognostic (1.54e-1)" "unprognostic (1.31e-3)" "unprognostic (4.37e-2)" "validated prognostic unfavorable (2.68e-7)" "validated prognostic unfavorable (2.75e-4)" "unprognostic (2.92e-1)" "potential prognostic unfavorable (2.99e-5)" "unprognostic (1.87e-2)" "unprognostic (1.57e-1)" "unprognostic (3.53e-2)" "unprognostic (2.96e-1)" "unprognostic (1.03e-1)" "unprognostic (9.52e-2)" "unprognostic (2.32e-1)" "potential prognostic favorable (1.79e-4)" "unprognostic (2.27e-2)" "unprognostic (1.50e-1)" "unprognostic (1.18e-1)" "unprognostic (2.13e-3)" "unprognostic (5.06e-2)" "unprognostic (8.68e-2)" "unprognostic (1.61e-1)" "unprognostic (3.19e-1)" "unprognostic (1.24e-1)" KCTD18 "6530404F10Rik, FLJ31322, FLJ37818" ENSG00000155729 "Potassium channel tetramerization domain containing 18" Q6PI47 2 200488958-200519784 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045498, HPA058028" Approved Approved Mitochondria NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 55: Breast - Lactation" "Cluster 19: Astrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" 3 Mitochondria "HPA045498: , HPA058028: " "unprognostic (1.53e-1)" "unprognostic (1.72e-2)" "unprognostic (4.26e-2)" "unprognostic (1.80e-2)" "unprognostic (5.81e-2)" "unprognostic (1.81e-1)" "unprognostic (2.94e-1)" "unprognostic (2.04e-2)" "unprognostic (7.50e-2)" "unprognostic (3.10e-2)" "potential prognostic favorable (1.42e-7)" "unprognostic (2.80e-2)" "unprognostic (1.19e-1)" "unprognostic (6.15e-2)" "unprognostic (1.72e-1)" "unprognostic (2.10e-1)" "unprognostic (1.41e-1)" "unprognostic (3.17e-1)" "unprognostic (2.47e-1)" "unprognostic (2.73e-1)" "unprognostic (1.55e-1)" "unprognostic (5.46e-2)" "unprognostic (5.67e-2)" "unprognostic (4.14e-1)" "unprognostic (7.09e-2)" "unprognostic (9.63e-2)" "unprognostic (1.02e-1)" "unprognostic (3.23e-1)" "unprognostic (1.36e-1)" "unprognostic (7.70e-2)" "unprognostic (2.03e-1)" KCTD19 FLJ40162 ENSG00000168676 "Potassium channel tetramerization domain containing 19" Q17RG1 16 67289428-67326760 "Predicted intracellular proteins" "Differentiation, Meiosis, Spermatogenesis, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "testis: 31.3" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 195.6;Early spermatids: 42.9;Late primary spermatocytes: 128.9;pDCs: 16.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 1.5;neutrophil: 2.7;plasmacytoid DC: 2.7" "Group enriched" "Detected in many" 6 "dendritic cells: 2.7;granulocytes: 2.7" "Low cancer specificity" "Detected in some" "Adipose visceral - Mesothelial cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049310, HPA053321" Uncertain NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 57: Testis - Spermatogenesis" "Cluster 6: Non-specific - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 3: Early primary spermatocytes - Early meiosis" 1 "HPA049310: , HPA053321: " "unprognostic (2.04e-1)" "unprognostic (8.28e-2)" "potential prognostic unfavorable (7.92e-4)" "unprognostic (2.27e-1)" "unprognostic (9.87e-2)" "unprognostic (1.07e-1)" "unprognostic (9.39e-2)" "unprognostic (9.01e-2)" "unprognostic (1.63e-1)" "potential prognostic unfavorable (3.19e-4)" KCTD2 KIAA0176 ENSG00000180901 "Potassium channel tetramerization domain containing 2" Q14681 17 75032575-75065889 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 194.2;Choroid plexus epithelial cells: 175.3" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 148.6" "Group enriched" "Detected in some" 6 "Ovary Serous Cystadenocarcinoma (TCGA): 7.0;Stomach Adenocarcinoma (TCGA): 6.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 2: Neurons - Nucleosome" "Cluster 40: Non-specific - Unknown function" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 9 "unprognostic (1.11e-1)" "unprognostic (1.95e-1)" "unprognostic (2.08e-1)" "unprognostic (2.85e-1)" "unprognostic (8.75e-3)" "unprognostic (1.59e-3)" "unprognostic (2.56e-1)" "unprognostic (9.90e-2)" "unprognostic (4.34e-1)" "unprognostic (1.13e-2)" "unprognostic (1.39e-1)" KCTD20 "C6orf69, dJ108K11.3, MGC14254" ENSG00000112078 "Potassium channel tetramerization domain containing 20" Q7Z5Y7 6 36442767-36491143 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 255.6;Neutrophils: 375.6;Platelets: 539.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030092 Approved Approved "Nuclear speckles,Endoplasmic reticulum" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 61: Non-specific - Transcription" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 3 "Endoplasmic reticulum" "Nuclear speckles" "HPA030092: " "unprognostic (6.97e-2)" "unprognostic (1.06e-1)" "unprognostic (8.51e-2)" "unprognostic (7.73e-2)" "unprognostic (1.61e-1)" "unprognostic (1.47e-2)" "unprognostic (4.61e-2)" "unprognostic (3.57e-3)" "unprognostic (5.93e-2)" "unprognostic (7.40e-2)" "potential prognostic favorable (1.44e-5)" "unprognostic (8.00e-3)" "unprognostic (7.13e-2)" "unprognostic (4.83e-3)" "unprognostic (1.08e-1)" "unprognostic (4.28e-1)" "unprognostic (1.98e-2)" "unprognostic (7.71e-2)" "unprognostic (1.36e-1)" "unprognostic (1.46e-1)" "unprognostic (3.10e-3)" "unprognostic (1.31e-1)" "unprognostic (3.92e-2)" "unprognostic (3.68e-2)" "unprognostic (1.55e-2)" "unprognostic (3.93e-2)" "unprognostic (6.66e-3)" "unprognostic (1.27e-1)" "unprognostic (9.29e-2)" "unprognostic (1.66e-3)" "unprognostic (4.09e-1)" KCTD21 KCASH2 ENSG00000188997 "Potassium channel tetramerization domain containing 21" Q4G0X4 11 78171249-78188626 "Predicted intracellular proteins" "Growth regulation, Ubl conjugation pathway" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 25.5;Adrenal medulla cells: 31.9;Esophageal apical cells: 29.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041964 Uncertain Approved Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 76: Non-specific - Metabolism" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 24: Non-specific - Unknown function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 15 Cytosol "HPA041964: " "unprognostic (2.49e-3)" "unprognostic (2.70e-1)" "unprognostic (8.76e-2)" "unprognostic (1.76e-3)" "unprognostic (1.29e-1)" "unprognostic (2.11e-1)" "unprognostic (2.74e-2)" "potential prognostic unfavorable (1.00e-5)" "unprognostic (1.11e-2)" "unprognostic (2.11e-3)" "unprognostic (8.88e-3)" "unprognostic (3.77e-1)" "unprognostic (1.51e-1)" "unprognostic (2.02e-1)" "unprognostic (1.28e-3)" "unprognostic (8.52e-2)" "unprognostic (3.61e-3)" "unprognostic (6.50e-2)" "unprognostic (2.06e-1)" "unprognostic (1.43e-1)" "unprognostic (1.51e-1)" "unprognostic (7.94e-3)" "unprognostic (3.49e-3)" "unprognostic (2.52e-1)" "unprognostic (3.30e-2)" "unprognostic (1.30e-1)" "unprognostic (3.67e-3)" "unprognostic (1.50e-1)" "unprognostic (2.68e-2)" "unprognostic (1.78e-1)" "unprognostic (6.31e-2)" KCTD3 NY-REN-45 ENSG00000136636 "Potassium channel tetramerization domain containing 3" Q9Y597 1 215567304-215621807 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adrenal cortex cells: 333.0;Esophageal apical cells: 219.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015142 Approved Approved Cytosol NA NA "Cluster 76: Non-specific - Metabolism" "Cluster 25: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 18: Adrenal cortex cells - Steroidogensis" 16 Cytosol "HPA015142: " "unprognostic (3.35e-1)" "unprognostic (2.23e-1)" "unprognostic (1.13e-1)" "unprognostic (8.06e-3)" "unprognostic (3.40e-3)" "unprognostic (3.51e-2)" "unprognostic (4.88e-2)" "unprognostic (1.03e-1)" "unprognostic (6.72e-2)" "unprognostic (2.26e-2)" "potential prognostic favorable (2.38e-4)" "unprognostic (1.25e-2)" "unprognostic (2.83e-2)" "unprognostic (1.09e-1)" "unprognostic (8.01e-2)" "potential prognostic unfavorable (2.99e-5)" "unprognostic (1.84e-2)" "unprognostic (2.03e-1)" "unprognostic (9.01e-2)" "unprognostic (1.78e-2)" "unprognostic (8.20e-3)" "unprognostic (1.24e-3)" "unprognostic (1.73e-1)" "unprognostic (2.73e-1)" "unprognostic (4.50e-2)" "unprognostic (1.29e-1)" "unprognostic (8.56e-2)" "unprognostic (4.10e-2)" "unprognostic (3.84e-1)" "unprognostic (1.70e-2)" "unprognostic (1.83e-1)" KCTD4 bA321C24.3 ENSG00000180332 "Potassium channel tetramerization domain containing 4" Q8WVF5 13 45192853-45201045 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "brain: 45.2" "Cell type enriched" "Detected in some" 4 "Retinal pigment epithelial cells: 72.5" "Cell type enhanced" "Detected in many" "hippocampal dentate gyrus: 37.4" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 1.8;Kidney Renal Papillary Cell Carcinoma (TCGA): 1.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 2.9;Kidney cancer: 8.0" "Adipose visceral - Mesothelial cells, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040734 Uncertain Approved "Centriolar satellite" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" 5 "Centriolar satellite" "HPA040734: " "potential prognostic favorable (8.59e-4)" "unprognostic (2.94e-1)" "unprognostic (1.96e-2)" "unprognostic (1.05e-1)" "unprognostic (2.02e-2)" KCTD5 FLJ20040 ENSG00000167977 "Potassium channel tetramerization domain containing 5" Q9NXV2 16 2682523-2709030 "Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 72.9;Esophageal apical cells: 174.7;Megakaryocytes: 68.0;pDCs: 93.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 63.7" "Group enriched" "Detected in all" 5 "dendritic cells: 63.7;granulocytes: 16.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 54: Non-specific - Transcription" "Cluster 65: Non-specific - Cell growth & division" 32 "unprognostic (4.61e-2)" "unprognostic (4.35e-3)" "unprognostic (2.00e-1)" "unprognostic (3.90e-1)" "unprognostic (6.96e-2)" "unprognostic (3.80e-1)" "unprognostic (2.26e-1)" "unprognostic (5.94e-2)" "unprognostic (6.81e-3)" "unprognostic (7.61e-2)" "unprognostic (1.15e-2)" "unprognostic (3.66e-2)" "unprognostic (9.70e-3)" "validated prognostic unfavorable (2.56e-5)" "validated prognostic unfavorable (1.08e-4)" "unprognostic (1.28e-2)" "potential prognostic unfavorable (3.52e-4)" "unprognostic (2.70e-2)" "unprognostic (1.39e-1)" "unprognostic (1.52e-1)" "unprognostic (5.70e-2)" "unprognostic (5.67e-3)" "unprognostic (2.33e-1)" "unprognostic (1.06e-2)" "unprognostic (1.74e-1)" "unprognostic (3.49e-1)" "unprognostic (9.84e-2)" "unprognostic (3.65e-2)" "unprognostic (4.72e-2)" "unprognostic (1.31e-1)" "unprognostic (2.08e-1)" KCTD6 "KCASH3, MGC27385" ENSG00000168301 "Potassium channel tetramerization domain containing 6" Q8NC69 3 58492096-58502360 "Predicted intracellular proteins" "Growth regulation, Ubl conjugation pathway" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036100, HPA036101" Uncertain Approved Nucleoli,Mitochondria NA NA "Cluster 41: Basophils - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 34: Non-specific - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 109: Neurons - Neuronal signaling" 40 "Nucleoli, Mitochondria" "HPA036100: , HPA036101: " "unprognostic (3.17e-1)" "unprognostic (6.96e-2)" "unprognostic (4.58e-1)" "unprognostic (1.55e-1)" "unprognostic (1.75e-1)" "unprognostic (5.37e-2)" "unprognostic (4.67e-3)" "unprognostic (2.61e-1)" "unprognostic (1.35e-1)" "unprognostic (4.23e-2)" "potential prognostic favorable (7.09e-4)" "unprognostic (2.11e-3)" "unprognostic (4.97e-2)" "potential prognostic unfavorable (1.79e-4)" "unprognostic (2.92e-2)" "unprognostic (1.86e-1)" "unprognostic (3.81e-3)" "unprognostic (5.05e-2)" "unprognostic (1.64e-2)" "unprognostic (5.03e-2)" "unprognostic (2.56e-1)" "unprognostic (1.54e-2)" "unprognostic (1.83e-2)" "unprognostic (6.40e-3)" "unprognostic (4.18e-2)" "unprognostic (5.78e-2)" "unprognostic (1.99e-1)" "unprognostic (1.90e-1)" "unprognostic (1.64e-1)" "unprognostic (2.46e-1)" "unprognostic (3.67e-1)" KCTD7 "CLN14, EPM3, FLJ32069" ENSG00000243335 "Potassium channel tetramerization domain containing 7" Q96MP8 7 66628881-66649067 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Epilepsy, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 60.9" "Cell type enhanced" "Detected in some" "Astrocytes: 29.0;Bergmann glia: 22.7;Brain excitatory neurons: 25.1;Brain inhibitory neurons: 28.9;Choroid plexus epithelial cells: 18.5;Ependymal cells: 21.7;Late spermatids: 19.2;Microglia: 87.5;Oligodendrocyte progenitor cells: 15.7;Oligodendrocytes: 52.7;Other brain neurons: 28.0;Tuft cells: 11.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 6 "unprognostic (1.02e-3)" "unprognostic (2.95e-1)" "unprognostic (1.13e-1)" "unprognostic (7.46e-2)" "unprognostic (2.89e-3)" "unprognostic (8.51e-3)" "unprognostic (4.93e-2)" "unprognostic (5.98e-2)" "unprognostic (5.90e-3)" "unprognostic (1.76e-3)" "unprognostic (2.63e-2)" "unprognostic (2.43e-1)" "unprognostic (1.61e-2)" "potential prognostic unfavorable (4.69e-5)" "unprognostic (2.73e-2)" "unprognostic (1.28e-1)" "unprognostic (1.72e-1)" "unprognostic (2.11e-1)" "unprognostic (2.84e-1)" "unprognostic (4.18e-2)" "unprognostic (1.70e-3)" "potential prognostic favorable (3.06e-4)" "unprognostic (3.35e-2)" "unprognostic (7.07e-2)" "unprognostic (3.11e-1)" "unprognostic (7.97e-2)" "unprognostic (7.43e-2)" "unprognostic (9.61e-2)" "unprognostic (3.83e-2)" "unprognostic (5.30e-2)" "unprognostic (3.58e-2)" KCTD8 ENSG00000183783 "Potassium channel tetramerization domain containing 8" Q6ZWB6 4 44173903-44448809 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 16.9;retina: 6.3" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 427.6;Brain inhibitory neurons: 521.7;Choroid plexus epithelial cells: 644.6;Ependymal cells: 309.2;Epicardial cells: 318.4;Mesothelial cells: 706.1;Myonuclei: 282.1;Oligodendrocyte progenitor cells: 400.7;Oligodendrocytes: 649.2;Renal connecting tubule cells: 314.8;Respiratory ionocytes: 266.7;Retinal ganglion cells: 289.7;Rod photoreceptor cells: 582.9;Sertoli cells: 586.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 2.1;Thyroid Carcinoma (TCGA): 1.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 2.2;Neuroblastoma: 1.9" "Adipose visceral - Mesothelial cells, Stomach - Chief cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA031562 Enhanced Approved "Cytoplasmic bodies" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 25: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" 1 "Cytoplasmic bodies" "HPA031562: " "unprognostic (1.16e-1)" "unprognostic (8.31e-3)" "unprognostic (7.68e-2)" "unprognostic (7.37e-2)" KCTD9 "BTBD27, FLJ20038" ENSG00000104756 "Potassium channel tetramerization domain containing 9" Q7L273 8 25427847-25458476 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 159.8;Innate lymphoid cells: 164.9" "Cell type enhanced" "Detected in all" "fibroblast: 210.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042468, HPA047902" Approved "Nucleoplasm,Intermediate filaments,Cytosol" No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 45: Non-specific - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 93 Nucleoplasm "Intermediate filaments, Cytosol" "HPA042468: , HPA047902: " "unprognostic (2.11e-2)" "unprognostic (5.00e-2)" "unprognostic (8.88e-2)" "unprognostic (1.87e-1)" "unprognostic (1.70e-3)" "unprognostic (2.14e-1)" "unprognostic (4.63e-2)" "unprognostic (1.01e-1)" "unprognostic (1.88e-2)" "unprognostic (5.88e-2)" "validated prognostic favorable (2.37e-5)" "validated prognostic favorable (7.99e-4)" "unprognostic (4.29e-2)" "unprognostic (1.24e-2)" "unprognostic (1.90e-2)" "unprognostic (2.19e-3)" "unprognostic (1.04e-1)" "unprognostic (2.42e-1)" "unprognostic (1.48e-1)" "unprognostic (1.96e-1)" "unprognostic (1.32e-3)" "unprognostic (3.65e-3)" "unprognostic (1.92e-2)" "unprognostic (3.59e-1)" "unprognostic (3.31e-2)" "unprognostic (3.78e-3)" "unprognostic (2.54e-1)" "unprognostic (1.47e-1)" "unprognostic (1.65e-1)" "potential prognostic unfavorable (8.45e-4)" "unprognostic (4.95e-2)" KDELR1 "ERD2, ERD2.1, HDEL" ENSG00000105438 "KDEL endoplasmic reticulum protein retention receptor 1" P24390 19 48382575-48391551 "Predicted membrane proteins, Transporters" "ER-Golgi transport, Protein transport, Transport" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 426.7;Extravillous trophoblasts: 815.9;Syncytiotrophoblasts: 437.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB017455 Approved Supported "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 70: Non-specific - Protein processing" "Cluster 36: Choroid plexus - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 8: Non-specific - Secretory pathway" 28 "Golgi apparatus" "Vesicles, Cytosol" "CAB017455: " "unprognostic (1.26e-1)" "unprognostic (3.32e-3)" "unprognostic (2.93e-2)" "unprognostic (1.50e-3)" "unprognostic (5.71e-2)" "unprognostic (7.94e-2)" "unprognostic (9.81e-2)" "unprognostic (1.25e-3)" "potential prognostic unfavorable (6.35e-4)" "unprognostic (9.95e-2)" "unprognostic (7.26e-3)" "unprognostic (6.54e-2)" "unprognostic (1.62e-1)" "validated prognostic unfavorable (1.55e-6)" "validated prognostic unfavorable (8.06e-6)" "unprognostic (3.63e-3)" "potential prognostic unfavorable (5.30e-4)" "unprognostic (1.11e-1)" "unprognostic (3.09e-1)" "unprognostic (1.41e-1)" "unprognostic (1.79e-1)" "unprognostic (2.05e-1)" "unprognostic (2.03e-1)" "unprognostic (1.60e-1)" "unprognostic (7.50e-2)" "unprognostic (8.12e-3)" "unprognostic (1.59e-1)" "unprognostic (1.03e-1)" "unprognostic (1.21e-1)" "unprognostic (5.96e-2)" "unprognostic (5.82e-2)" KDELR2 "ELP-1, ERD2.2" ENSG00000136240 "KDEL endoplasmic reticulum protein retention receptor 2" P33947 7 6445953-6484190 "Disease related genes, Human disease related genes, Predicted membrane proteins" "ER-Golgi transport, Protein transport, Transport" Receptor "Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 406.1;Late primary spermatocytes: 486.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Spleen - Fibroblasts_1, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016459 Approved NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 67: Non-specific - Unknown function" "Cluster 67: Plasma cells - Plasma cell differentiation" "HPA016459: " "unprognostic (1.28e-1)" "unprognostic (1.69e-3)" "unprognostic (4.67e-2)" "potential prognostic unfavorable (3.73e-5)" "unprognostic (2.17e-1)" "unprognostic (2.15e-1)" "potential prognostic unfavorable (4.09e-4)" "unprognostic (3.60e-3)" "potential prognostic unfavorable (8.62e-5)" "unprognostic (3.85e-3)" "potential prognostic favorable (4.30e-4)" "unprognostic (5.51e-3)" "unprognostic (1.66e-2)" "unprognostic (6.43e-2)" "potential prognostic unfavorable (1.41e-4)" "unprognostic (2.23e-3)" "unprognostic (1.47e-2)" "unprognostic (1.95e-1)" "unprognostic (2.25e-1)" "unprognostic (7.92e-2)" "unprognostic (2.29e-2)" "unprognostic (5.67e-3)" "unprognostic (3.03e-1)" "unprognostic (1.52e-1)" "unprognostic (2.34e-1)" "unprognostic (1.84e-3)" "unprognostic (1.80e-1)" "unprognostic (7.86e-2)" "unprognostic (1.43e-1)" "unprognostic (1.14e-2)" "unprognostic (1.71e-2)" KDELR3 ENSG00000100196 "KDEL endoplasmic reticulum protein retention receptor 3" O43731 22 38468078-38483447 "Predicted membrane proteins" "ER-Golgi transport, Protein transport, Transport" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 48.4;Extravillous trophoblasts: 112.6;Gastric chief cells: 56.8;Gastric progenitor cells: 80.7;Goblet cells: 57.5;Hepatic stellate cells: 154.9;Lacrimal acinar cells: 48.0" "Cell type enhanced" "Detected in many" "ependymal cell: 6.1;fibroblast: 6.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.6" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Skeletal muscle - Fibroblasts, Skin - Fibroblasts_1, Spleen - Fibroblasts_1, Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043477, HPA076405" Uncertain Supported "Endoplasmic reticulum" No No "Cluster 14: Non-specific - Unknown function" "Cluster 60: Stomach - Digestion" "Cluster 16: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 19 "Endoplasmic reticulum" "HPA043477: , HPA076405: " "unprognostic (1.65e-2)" "unprognostic (1.34e-1)" "unprognostic (1.61e-1)" "unprognostic (9.63e-2)" "unprognostic (2.60e-1)" "unprognostic (6.39e-2)" "unprognostic (2.48e-1)" "potential prognostic unfavorable (2.77e-4)" "unprognostic (4.36e-2)" "unprognostic (3.11e-1)" "validated prognostic unfavorable (1.47e-8)" "validated prognostic unfavorable (2.30e-4)" "unprognostic (1.80e-3)" "potential prognostic unfavorable (2.09e-4)" "unprognostic (1.64e-2)" "unprognostic (5.79e-2)" "unprognostic (2.21e-2)" "unprognostic (2.97e-1)" "unprognostic (2.08e-1)" "unprognostic (3.13e-1)" "unprognostic (3.08e-2)" "unprognostic (1.69e-2)" "unprognostic (1.56e-1)" "unprognostic (9.75e-2)" "unprognostic (1.66e-1)" "unprognostic (2.55e-2)" "unprognostic (2.96e-1)" "unprognostic (1.26e-1)" "unprognostic (1.61e-1)" "unprognostic (7.41e-2)" "unprognostic (4.27e-1)" KDF1 "C1orf172, FLJ34633, RP11-344H11.3" ENSG00000175707 "Keratinocyte differentiation factor 1" Q8NAX2 1 26949562-26960468 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Differentiation "Developmental protein" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 38.3;Epididymal principal cells: 65.9;Esophageal apical cells: 69.4;Esophageal basal cells: 39.7;Esophageal suprabasal cells: 44.9;Extravillous trophoblasts: 36.9;Migrating cytotrophoblasts: 36.4;Syncytiotrophoblasts: 38.3" "Cell type enhanced" "Detected in single" "cerebellar inhibitory: 1.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 36 "B-cells: 3.4;T-cells: 6.2" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Skin - Keratinocyte (other), Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA028634, HPA028639" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 70: Non-specific - Protein processing" "Cluster 15: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" 5 "Plasma membrane" Cytosol "HPA028634: , HPA028639: " "unprognostic (1.97e-1)" "unprognostic (2.10e-1)" "unprognostic (6.73e-2)" "unprognostic (3.64e-3)" "unprognostic (3.14e-1)" "unprognostic (4.78e-2)" "unprognostic (1.26e-1)" "validated prognostic favorable (5.34e-9)" "validated prognostic favorable (3.48e-10)" "unprognostic (5.16e-3)" "unprognostic (8.82e-2)" "unprognostic (7.74e-2)" "unprognostic (9.30e-2)" "unprognostic (1.39e-1)" "unprognostic (4.45e-1)" "unprognostic (4.33e-2)" "unprognostic (1.78e-2)" "unprognostic (1.17e-1)" "unprognostic (1.66e-2)" "unprognostic (1.21e-1)" "unprognostic (1.02e-1)" "unprognostic (5.78e-2)" "unprognostic (3.61e-2)" "unprognostic (5.27e-3)" "unprognostic (2.36e-2)" "unprognostic (9.59e-2)" "unprognostic (1.11e-2)" KDM1A "AOF2, BHC110, KDM1, KIAA0601, LSD1" ENSG00000004487 "Lysine demethylase 1A" O60341 1 23019443-23083689 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Developmental protein, Oxidoreductase, Repressor" "Cushing syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005884, HPA053660" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 37: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 312 Nucleoplasm Cytosol "CAB005884: , HPA053660: " "unprognostic (2.16e-2)" "unprognostic (9.67e-2)" "unprognostic (6.20e-3)" "unprognostic (7.65e-2)" "potential prognostic favorable (6.70e-4)" "unprognostic (6.31e-2)" "unprognostic (1.84e-1)" "potential prognostic favorable (2.28e-4)" "unprognostic (3.56e-2)" "unprognostic (1.37e-2)" "unprognostic (3.59e-3)" "unprognostic (1.71e-2)" "unprognostic (2.13e-1)" "validated prognostic unfavorable (1.41e-10)" "validated prognostic unfavorable (2.06e-5)" "unprognostic (7.56e-2)" "unprognostic (1.96e-2)" "unprognostic (1.29e-1)" "unprognostic (2.31e-2)" "unprognostic (2.08e-1)" "unprognostic (1.13e-1)" "unprognostic (1.79e-3)" "unprognostic (2.96e-1)" "unprognostic (1.47e-1)" "unprognostic (1.72e-1)" "unprognostic (9.88e-3)" "unprognostic (9.30e-2)" "unprognostic (1.08e-1)" "unprognostic (3.35e-2)" "unprognostic (2.37e-1)" "unprognostic (4.23e-3)" KDM1B "AOF1, bA204B7.3, C6orf193, dJ298J15.2, FLJ33898, FLJ34109, FLJ43328, LSD2" ENSG00000165097 "Lysine demethylase 1B" Q8NB78 6 18155329-18223854 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Developmental protein, Oxidoreductase, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophil progenitors: 290.4;Neutrophils: 250.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "dendritic cells: 3.7;granulocytes: 7.2;monocytes: 8.6" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031269, HPA055597" Uncertain Enhanced Nucleoplasm NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 40: Non-specific - Mixed function" "Cluster 46: Brainstem - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 11 Nucleoplasm "HPA031269: , HPA055597: " "unprognostic (2.68e-1)" "unprognostic (4.37e-2)" "unprognostic (1.58e-1)" "unprognostic (1.01e-3)" "unprognostic (1.76e-1)" "unprognostic (2.19e-2)" "unprognostic (6.98e-2)" "unprognostic (5.86e-2)" "unprognostic (5.95e-2)" "unprognostic (1.04e-1)" "potential prognostic favorable (3.25e-7)" "unprognostic (3.99e-2)" "unprognostic (2.33e-1)" "unprognostic (5.72e-2)" "unprognostic (5.37e-2)" "unprognostic (1.48e-1)" "unprognostic (1.02e-1)" "unprognostic (1.95e-1)" "unprognostic (3.95e-2)" "unprognostic (7.66e-2)" "unprognostic (5.11e-2)" "unprognostic (2.39e-1)" "unprognostic (9.61e-2)" "unprognostic (2.19e-2)" "potential prognostic favorable (1.01e-4)" "unprognostic (5.27e-2)" "unprognostic (2.44e-2)" "unprognostic (1.98e-1)" "unprognostic (1.47e-1)" "unprognostic (3.97e-2)" "unprognostic (3.41e-2)" KDM2A "CXXC8, DKFZP434M1735, FBL11, FBL7, FBXL11, FLJ00115, JHDM1A, KIAA1004, LILINA" ENSG00000173120 "Lysine demethylase 2A" Q9Y2K7 11 67119263-67258082 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation, Ubl conjugation pathway" "Chromatin regulator, Dioxygenase, DNA-binding, Oxidoreductase, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 1465.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012272, HPA044251" Supported Supported Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 39: Testis - Nuclear processes" "Cluster 15: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" 17 Nucleoplasm "CAB012272: , HPA044251: " "unprognostic (1.68e-1)" "unprognostic (9.24e-2)" "unprognostic (4.90e-2)" "unprognostic (1.03e-1)" "unprognostic (5.24e-1)" "unprognostic (5.79e-3)" "unprognostic (1.56e-1)" "unprognostic (3.38e-1)" "unprognostic (5.44e-3)" "unprognostic (2.44e-2)" "potential prognostic favorable (5.51e-4)" "unprognostic (1.08e-2)" "unprognostic (8.04e-2)" "unprognostic (2.86e-1)" "unprognostic (2.44e-2)" "unprognostic (2.97e-1)" "unprognostic (3.25e-3)" "unprognostic (2.11e-1)" "unprognostic (8.28e-2)" "unprognostic (2.80e-3)" "unprognostic (2.15e-1)" "unprognostic (1.62e-2)" "potential prognostic unfavorable (4.66e-4)" "unprognostic (1.40e-1)" "unprognostic (6.95e-3)" "unprognostic (1.53e-3)" "unprognostic (2.86e-1)" "unprognostic (2.44e-1)" "unprognostic (2.41e-1)" "unprognostic (5.95e-2)" "unprognostic (7.17e-2)" KDM2B "CXXC2, Fbl10, FBXL10, JHDM1B, PCCX2" ENSG00000089094 "Lysine demethylase 2B" Q8NHM5 12 121429096-121581023 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Chromatin regulator, Dioxygenase, DNA-binding, Oxidoreductase, Repressor, RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "cDC: 227.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - T-cells, Skin - Keratinocyte (other), Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071257 Supported Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 49: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 82: Dendritic cells - Antigen presentation" 30 Nucleoplasm "HPA071257: " "unprognostic (1.05e-1)" "unprognostic (5.51e-2)" "unprognostic (1.84e-2)" "unprognostic (1.96e-1)" "unprognostic (1.10e-1)" "unprognostic (2.17e-1)" "unprognostic (2.56e-1)" "potential prognostic favorable (1.34e-4)" "potential prognostic favorable (6.51e-4)" "unprognostic (9.48e-3)" "unprognostic (1.62e-1)" "unprognostic (1.90e-1)" "unprognostic (1.03e-1)" "unprognostic (9.06e-2)" "unprognostic (3.99e-1)" "unprognostic (1.48e-1)" "unprognostic (1.55e-1)" "unprognostic (7.72e-2)" "unprognostic (1.04e-3)" "unprognostic (1.63e-1)" "unprognostic (1.27e-3)" "unprognostic (1.84e-2)" "unprognostic (6.63e-3)" "unprognostic (8.31e-2)" "unprognostic (8.72e-3)" "potential prognostic favorable (2.98e-4)" "unprognostic (5.89e-2)" "unprognostic (2.94e-2)" "unprognostic (2.95e-2)" "unprognostic (1.36e-2)" "unprognostic (3.29e-2)" KDM3A "JHMD2A, JMJD1, JMJD1A, KIAA0742, TSGA" ENSG00000115548 "Lysine demethylase 3A" Q9Y4C1 2 86440647-86492716 "Enzymes, Predicted intracellular proteins" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Activator, Chromatin regulator, Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055543, HPA065162" Supported Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 40: Non-specific - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 8 Nucleoplasm "HPA055543: , HPA065162: " "unprognostic (2.74e-1)" "unprognostic (3.66e-3)" "unprognostic (8.07e-2)" "unprognostic (9.02e-3)" "unprognostic (3.64e-2)" "unprognostic (2.50e-1)" "unprognostic (1.41e-1)" "unprognostic (2.39e-2)" "unprognostic (5.40e-2)" "potential prognostic unfavorable (3.86e-4)" "potential prognostic favorable (5.03e-5)" "unprognostic (2.05e-2)" "unprognostic (1.22e-2)" "potential prognostic unfavorable (9.48e-6)" "unprognostic (9.07e-3)" "unprognostic (4.35e-1)" "unprognostic (1.29e-2)" "unprognostic (1.41e-1)" "unprognostic (3.14e-2)" "unprognostic (7.24e-3)" "unprognostic (9.31e-2)" "unprognostic (5.79e-3)" "unprognostic (5.22e-3)" "unprognostic (1.44e-1)" "unprognostic (1.80e-1)" "unprognostic (1.22e-1)" "unprognostic (4.62e-3)" "unprognostic (1.19e-1)" "unprognostic (1.91e-1)" "unprognostic (6.15e-2)" "unprognostic (3.64e-1)" KDM3B "C5orf7, JMJD1B, KIAA1082, NET22" ENSG00000120733 "Lysine demethylase 3B" Q7LBC6 5 138352685-138437028 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Dioxygenase, Oxidoreductase" "Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 533.6;pDCs: 435.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016610, HPA057202" Supported Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 9 Nucleoplasm "Golgi apparatus" "HPA016610: , HPA057202: " "unprognostic (1.02e-1)" "unprognostic (5.93e-2)" "unprognostic (3.35e-1)" "unprognostic (3.73e-1)" "unprognostic (1.58e-2)" "unprognostic (1.77e-1)" "unprognostic (1.26e-1)" "unprognostic (1.27e-2)" "unprognostic (1.18e-1)" "unprognostic (1.64e-1)" "validated prognostic favorable (5.78e-7)" "validated prognostic favorable (1.16e-4)" "unprognostic (5.81e-2)" "unprognostic (1.80e-2)" "unprognostic (7.18e-2)" "unprognostic (5.05e-2)" "unprognostic (2.02e-1)" "unprognostic (2.72e-1)" "unprognostic (4.08e-1)" "unprognostic (5.31e-2)" "unprognostic (1.36e-1)" "unprognostic (8.40e-2)" "unprognostic (3.23e-1)" "unprognostic (1.05e-1)" "unprognostic (2.07e-2)" "unprognostic (1.36e-1)" "unprognostic (6.93e-2)" "unprognostic (1.13e-1)" "unprognostic (4.05e-1)" "unprognostic (2.26e-1)" "unprognostic (3.53e-1)" KDM4A "JHDM3A, JMJD2, JMJD2A, KIAA0677, TDRD14A" ENSG00000066135 "Lysine demethylase 4A" O75164 1 43650149-43705518 "Enzymes, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 26.5;Bergmann glia: 26.8;Brain excitatory neurons: 28.5;Brain inhibitory neurons: 31.4;Choroid plexus epithelial cells: 39.2;Ependymal cells: 36.0;Microglia: 30.5;Oligodendrocyte progenitor cells: 29.1;Oligodendrocytes: 34.7;Other brain neurons: 21.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007610 Uncertain Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 77: Intestine - Digestion" "Cluster 31: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 22: Non-specific - Basic cellular functions" 34 "Nucleoli fibrillar center" Nucleoplasm "HPA007610: " "unprognostic (3.96e-3)" "unprognostic (1.01e-1)" "unprognostic (2.72e-1)" "unprognostic (2.94e-2)" "unprognostic (1.19e-1)" "unprognostic (1.11e-1)" "unprognostic (7.73e-2)" "potential prognostic favorable (3.80e-5)" "unprognostic (1.00e-2)" "unprognostic (6.62e-3)" "potential prognostic favorable (2.89e-4)" "unprognostic (8.29e-2)" "unprognostic (3.26e-1)" "potential prognostic unfavorable (9.37e-5)" "unprognostic (1.04e-1)" "unprognostic (2.61e-3)" "unprognostic (1.73e-1)" "unprognostic (2.75e-1)" "unprognostic (1.22e-2)" "unprognostic (2.63e-1)" "unprognostic (3.05e-1)" "unprognostic (8.52e-2)" "unprognostic (4.03e-1)" "unprognostic (1.18e-1)" "unprognostic (4.44e-2)" "unprognostic (1.24e-1)" "unprognostic (1.07e-1)" "unprognostic (2.11e-2)" "unprognostic (4.31e-1)" "unprognostic (1.47e-1)" "unprognostic (1.12e-1)" KDM4B "JMJD2B, KIAA0876, TDRD14B" ENSG00000127663 "Lysine demethylase 4B" O94953 19 4969113-5153598 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Dioxygenase, Oxidoreductase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 748.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 5.1;dendritic cells: 1.7;granulocytes: 4.6" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Breast - Breast glandular cells, Prostate - Prostate glandular cells, Spleen - B-cells (Spleen), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071568 Supported Nucleoplasm,Cytosol NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 24: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 23: Non-specific - Transcription" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 31 Nucleoplasm Cytosol "HPA071568: " "unprognostic (3.44e-2)" "unprognostic (1.73e-2)" "unprognostic (4.64e-1)" "unprognostic (9.84e-2)" "unprognostic (3.47e-1)" "unprognostic (8.90e-2)" "unprognostic (1.12e-1)" "unprognostic (2.25e-2)" "unprognostic (1.08e-3)" "unprognostic (3.18e-2)" "unprognostic (2.81e-3)" "unprognostic (1.97e-1)" "unprognostic (4.25e-2)" "unprognostic (4.64e-2)" "unprognostic (2.61e-1)" "unprognostic (2.77e-1)" "unprognostic (1.56e-1)" "unprognostic (2.44e-1)" "unprognostic (3.55e-2)" "unprognostic (1.05e-1)" "unprognostic (3.98e-1)" "unprognostic (8.04e-3)" "unprognostic (2.93e-3)" "unprognostic (3.46e-2)" "unprognostic (5.23e-2)" "unprognostic (4.30e-2)" "unprognostic (1.47e-2)" "unprognostic (2.26e-1)" "unprognostic (9.04e-2)" "unprognostic (1.68e-2)" "potential prognostic favorable (4.33e-5)" KDM4C "GASC1, JMJD2C, KIAA0780, TDRD14C" ENSG00000107077 "Lysine demethylase 4C" Q9H3R0 9 6720863-7175648 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069357 Approved Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 47: Leukemia - Hemostasis" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 4 Nucleoplasm "HPA069357: " "unprognostic (6.11e-2)" "unprognostic (9.52e-2)" "unprognostic (2.11e-2)" "unprognostic (4.50e-2)" "unprognostic (1.13e-2)" "unprognostic (3.31e-2)" "unprognostic (3.18e-1)" "unprognostic (6.08e-2)" "unprognostic (2.82e-1)" "unprognostic (2.84e-1)" "validated prognostic favorable (3.50e-6)" "validated prognostic favorable (3.82e-5)" "unprognostic (1.54e-1)" "unprognostic (5.10e-3)" "unprognostic (2.61e-1)" "unprognostic (7.00e-3)" "unprognostic (4.40e-2)" "unprognostic (2.05e-1)" "unprognostic (2.81e-1)" "unprognostic (3.48e-1)" "unprognostic (1.20e-1)" "unprognostic (4.68e-2)" "unprognostic (8.79e-3)" "unprognostic (5.26e-2)" "unprognostic (9.60e-2)" "unprognostic (1.02e-1)" "unprognostic (1.27e-1)" "unprognostic (1.60e-1)" "unprognostic (2.73e-1)" "unprognostic (2.85e-1)" "unprognostic (4.29e-2)" KDM4D "FLJ10251, JMJD2D" ENSG00000186280 "Lysine demethylase 4D" Q6B0I6 11 94973709-94999519 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "testis: 31.1" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 41.2;Early spermatids: 92.2;Late primary spermatocytes: 244.9;Late spermatids: 55.4;Sertoli cells: 31.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 2.2" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA055854, HPA064037" Approved Approved Nucleoplasm NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 57: Testis - Spermatogenesis" "Cluster 55: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 2 Nucleoplasm "HPA055854: , HPA064037: " "unprognostic (1.24e-2)" "unprognostic (2.59e-1)" "unprognostic (6.30e-2)" "unprognostic (3.91e-1)" "unprognostic (3.40e-1)" "unprognostic (4.17e-2)" "unprognostic (4.93e-2)" "unprognostic (3.17e-1)" KDM4E "JMJD2E, KDM4DL, KDM5E" ENSG00000235268 "Lysine demethylase 4E" B2RXH2 11 95025258-95027596 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Dioxygenase, Oxidoreductase" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA051740, HPA054225" Uncertain NA NA "Cluster 4: Non-specific - Transcription" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "HPA051740: , HPA054225: " KDM4F JMJD2F ENSG00000255855 "Lysine demethylase 4F" 11 95049422-95051338 "Enzymes, Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 57: Stomach & Colon cancer - Digestion" KDM5A "JARID1A, RBBP2" ENSG00000073614 "Lysine demethylase 5A" P29375 12 280057-389320 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, Dioxygenase, Oxidoreductase" "Autism, Autism spectrum disorder, Cancer-related genes, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 42.9" "Cell type enhanced" "Detected in all" "Neutrophils: 483.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006201 Supported "Nuclear bodies,Cytosol" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 22 "Nuclear bodies" Cytosol "HPA006201: " "unprognostic (2.64e-1)" "unprognostic (7.11e-2)" "unprognostic (1.07e-1)" "unprognostic (2.12e-2)" "unprognostic (1.11e-1)" "unprognostic (7.00e-3)" "unprognostic (9.50e-2)" "unprognostic (5.32e-3)" "unprognostic (2.63e-1)" "potential prognostic unfavorable (9.53e-4)" "validated prognostic favorable (1.56e-4)" "validated prognostic favorable (5.00e-4)" "unprognostic (2.52e-2)" "unprognostic (1.43e-2)" "unprognostic (8.54e-2)" "unprognostic (2.22e-1)" "unprognostic (1.45e-2)" "unprognostic (8.04e-2)" "unprognostic (1.62e-1)" "unprognostic (9.62e-2)" "unprognostic (2.41e-3)" "unprognostic (1.80e-3)" "potential prognostic unfavorable (3.51e-4)" "unprognostic (2.67e-1)" "unprognostic (1.44e-2)" "unprognostic (1.87e-3)" "unprognostic (5.15e-2)" "unprognostic (6.42e-2)" "unprognostic (3.15e-1)" "unprognostic (1.94e-2)" "unprognostic (1.69e-1)" KDM5B "CT31, JARID1B, PLU-1, PPP1R98, RBBP2H1A" ENSG00000117139 "Lysine demethylase 5B" Q9UGL1 1 202724495-202808487 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, Dioxygenase, Oxidoreductase, Repressor" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 34.5" "Cell type enhanced" "Detected in all" "Rod photoreceptor cells: 843.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Liver - Vascular endothelial cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027179, HPA053723, CAB068193" Enhanced Supported Nucleoplasm,Cytosol NA Yes "Cluster 46: Basophils - Proteolysis" "Cluster 47: Testis - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 79: Photoreceptor cells - Phototransduction" 13 Nucleoplasm Cytosol "CAB068193: , HPA027179: , HPA053723: " "unprognostic (5.26e-2)" "unprognostic (1.16e-1)" "unprognostic (1.21e-1)" "unprognostic (1.34e-3)" "unprognostic (9.27e-2)" "unprognostic (1.41e-2)" "unprognostic (3.11e-2)" "unprognostic (3.23e-3)" "unprognostic (9.64e-2)" "unprognostic (1.08e-1)" "potential prognostic favorable (4.48e-4)" "unprognostic (3.79e-1)" "unprognostic (5.42e-2)" "unprognostic (2.70e-2)" "unprognostic (8.57e-2)" "unprognostic (1.16e-1)" "unprognostic (3.51e-3)" "unprognostic (5.24e-2)" "unprognostic (1.93e-1)" "unprognostic (3.56e-2)" "unprognostic (7.80e-3)" "unprognostic (5.04e-2)" "unprognostic (1.01e-1)" "unprognostic (1.96e-1)" "unprognostic (1.86e-2)" "unprognostic (1.96e-1)" "unprognostic (4.81e-2)" "unprognostic (1.19e-1)" "unprognostic (1.65e-1)" "unprognostic (1.93e-3)" "unprognostic (2.28e-1)" KDM5C "DXS1272E, JARID1C, MRX13, SMCX, XE169" ENSG00000126012 "Lysine demethylase 5C" P41229 X 53176283-53225422 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, Dioxygenase, Oxidoreductase, Repressor" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "HPA038244, HPA046147" Supported Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 49: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 36: Non-specific - mRNA processing" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 7 Nucleoplasm Cytosol "HPA038244: , HPA046147: " "unprognostic (1.07e-1)" "unprognostic (3.99e-2)" "unprognostic (2.29e-1)" "unprognostic (1.76e-2)" "unprognostic (4.83e-2)" "unprognostic (1.19e-2)" "unprognostic (1.62e-1)" "unprognostic (2.02e-1)" "unprognostic (2.40e-2)" "unprognostic (9.66e-3)" "unprognostic (1.71e-1)" "unprognostic (2.79e-2)" "unprognostic (1.00e-1)" "potential prognostic unfavorable (3.09e-5)" "unprognostic (3.65e-2)" "unprognostic (2.13e-1)" "unprognostic (2.63e-3)" "unprognostic (1.20e-1)" "unprognostic (5.31e-3)" "unprognostic (6.48e-2)" "unprognostic (2.90e-1)" "unprognostic (5.37e-2)" "unprognostic (9.97e-2)" "unprognostic (2.38e-1)" "unprognostic (2.05e-2)" "unprognostic (2.45e-1)" "unprognostic (7.34e-2)" "unprognostic (5.43e-2)" "unprognostic (2.03e-1)" "unprognostic (1.17e-1)" "unprognostic (1.81e-2)" KDM5D "HY, HYA, JARID1D, KIAA0234, SMCY" ENSG00000012817 "Lysine demethylase 5D" Q9BY66 Y 19703865-19744939 "Enzymes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Leydig cells: 84.5;Myonuclei: 83.6;Oligodendrocytes: 80.2;Retinal bipolar cells: 91.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "testis cancer: 25.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049086 Approved "Nucleoli fibrillar center" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 5: Spleen - Immune response" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 47: Leukemia - Hemostasis" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 4 "Nucleoli fibrillar center" "HPA049086: " "unprognostic (8.37e-2)" "unprognostic (1.77e-2)" "unprognostic (1.79e-1)" "unprognostic (3.10e-1)" "unprognostic (1.26e-2)" "potential prognostic favorable (1.32e-4)" "unprognostic (7.13e-2)" "unprognostic (1.68e-1)" "unprognostic (1.54e-1)" "unprognostic (4.32e-2)" "unprognostic (8.67e-3)" "unprognostic (9.42e-3)" "unprognostic (2.93e-1)" "unprognostic (3.51e-2)" "unprognostic (5.00e-2)" "unprognostic (3.81e-1)" "unprognostic (8.27e-2)" "unprognostic (2.15e-1)" "unprognostic (1.12e-1)" "unprognostic (5.75e-3)" "unprognostic (2.40e-2)" "unprognostic (1.65e-2)" "unprognostic (6.06e-2)" "unprognostic (1.70e-1)" "unprognostic (2.70e-2)" KDM6A UTX ENSG00000147050 "Lysine demethylase 6A" O15550 X 44873188-45112779 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Chromatin regulator, Dioxygenase, Oxidoreductase" "Cancer-related genes, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 1305.9;Neutrophils: 1251.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000568, HPA001165, HPA002111" Enhanced Approved "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 54: Non-specific - Ribosome" "Cluster 11: White matter - Signal transduction" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 31 "Nucleoli, Nucleoli rim" Nucleoplasm "HPA000568: , HPA001165: , HPA002111: " "unprognostic (2.15e-2)" "unprognostic (5.81e-3)" "unprognostic (2.07e-1)" "unprognostic (3.83e-2)" "unprognostic (3.81e-3)" "unprognostic (6.59e-2)" "unprognostic (1.58e-1)" "unprognostic (3.31e-1)" "unprognostic (7.68e-2)" "unprognostic (4.89e-1)" "unprognostic (1.10e-1)" "unprognostic (6.51e-2)" "unprognostic (2.11e-1)" "potential prognostic unfavorable (1.80e-4)" "unprognostic (1.75e-1)" "unprognostic (1.66e-1)" "unprognostic (1.14e-1)" "unprognostic (2.98e-2)" "unprognostic (8.95e-2)" "unprognostic (7.48e-2)" "unprognostic (2.50e-1)" "unprognostic (2.29e-2)" "unprognostic (3.20e-1)" "unprognostic (1.55e-1)" "unprognostic (1.21e-1)" "unprognostic (3.75e-3)" "unprognostic (1.73e-1)" "unprognostic (7.95e-2)" "unprognostic (2.25e-2)" "unprognostic (1.11e-1)" "unprognostic (1.34e-2)" KDM6B "JMJD3, KIAA0346" ENSG00000132510 "Lysine demethylase 6B" O15054 17 7834217-7854796 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Inflammatory response" "Chromatin regulator, Dioxygenase, Oxidoreductase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epicardial cells: 600.4;Epididymal basal cells: 398.4;Mast cells: 321.6;monocytes: 350.3;Neutrophils: 857.5;Ocular epithelial cells: 282.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 3.6;neutrophil: 8.9" "Lineage enriched" "Detected in single" 12 "granulocytes: 8.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037988 Supported Approved "Nuclear speckles" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 15: Non-specific - Transcription" "Cluster 42: Non-specific - Unknown function" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 6 "Nuclear speckles" "HPA037988: " "unprognostic (2.27e-1)" "unprognostic (2.09e-1)" "unprognostic (8.97e-2)" "unprognostic (1.01e-2)" "unprognostic (1.23e-1)" "unprognostic (4.75e-3)" "unprognostic (1.62e-1)" "unprognostic (2.17e-1)" "unprognostic (2.80e-1)" "unprognostic (8.73e-2)" "potential prognostic favorable (5.02e-5)" "unprognostic (2.36e-3)" "unprognostic (4.43e-3)" "unprognostic (6.59e-2)" "unprognostic (4.73e-3)" "unprognostic (1.36e-1)" "unprognostic (1.43e-1)" "unprognostic (1.59e-2)" "unprognostic (1.87e-2)" "unprognostic (4.12e-2)" "unprognostic (4.59e-1)" "unprognostic (9.04e-3)" "unprognostic (7.59e-3)" "unprognostic (1.27e-2)" "unprognostic (1.53e-1)" "unprognostic (1.48e-2)" "unprognostic (2.24e-1)" "unprognostic (6.94e-2)" "unprognostic (1.56e-1)" "potential prognostic unfavorable (1.22e-4)" "unprognostic (7.39e-2)" KDM7A "JHDM1D, KIAA1718" ENSG00000006459 "Lysine demethylase 7A" Q6ZMT4 7 140084746-140176983 "Enzymes, Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" "Chromatin regulator, Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 318.5;Neutrophil progenitors: 425.8;Neutrophils: 627.1" "Cell type enhanced" "Detected in all" "endothelial cell: 263.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Stomach - Gastric mucous cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012114 Uncertain Approved Nucleoplasm,Nucleoli Yes No "Cluster 7: Non-specific - Innate immune response" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 32: Non-specific - Cell proliferation" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 1 Nucleoplasm Nucleoli "HPA012114: " "unprognostic (1.38e-3)" "unprognostic (1.64e-1)" "unprognostic (8.04e-3)" "unprognostic (6.39e-2)" "unprognostic (8.14e-2)" "unprognostic (1.11e-1)" "unprognostic (1.09e-3)" "unprognostic (6.65e-2)" "unprognostic (7.89e-2)" "validated prognostic favorable (1.44e-5)" "validated prognostic favorable (1.51e-4)" "unprognostic (2.58e-1)" "unprognostic (2.19e-2)" "unprognostic (3.77e-2)" "unprognostic (1.40e-1)" "potential prognostic favorable (2.71e-4)" "unprognostic (1.16e-2)" "unprognostic (5.84e-2)" "unprognostic (3.83e-3)" "unprognostic (1.10e-1)" "unprognostic (2.73e-1)" "unprognostic (1.04e-2)" "unprognostic (2.23e-1)" "unprognostic (1.06e-1)" "unprognostic (1.79e-1)" "unprognostic (1.19e-1)" "unprognostic (8.51e-2)" "unprognostic (3.00e-1)" KDM8 "FLJ13798, JMJD5" ENSG00000155666 "Lysine demethylase 8" Q8N371 16 27203508-27221768 "Enzymes, Essential proteins, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Transcription, Transcription regulation" "Aminopeptidase, Chromatin regulator, Dioxygenase, Hydrolase, Oxidoreductase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "liver: 78.1" "Group enriched" "Detected in many" 5 "Enterocytes: 48.3;Hepatocytes: 85.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026545 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 15: Non-specific - Transcription" "Cluster 54: Non-specific - Transcription" "Cluster 93: Hepatocytes - Bile production & excretion" 7 Nucleoplasm Cytosol "HPA026545: " "unprognostic (1.70e-1)" "unprognostic (1.26e-1)" "unprognostic (4.59e-2)" "unprognostic (4.13e-2)" "unprognostic (3.12e-2)" "unprognostic (1.01e-1)" "unprognostic (2.40e-2)" "unprognostic (1.07e-1)" "unprognostic (1.40e-1)" "unprognostic (3.25e-2)" "unprognostic (1.11e-1)" "potential prognostic favorable (8.66e-4)" "unprognostic (6.71e-3)" "unprognostic (2.09e-2)" "unprognostic (1.33e-1)" "unprognostic (2.35e-1)" "unprognostic (2.87e-1)" "unprognostic (8.37e-2)" "unprognostic (4.67e-1)" "potential prognostic favorable (4.50e-5)" "unprognostic (7.50e-2)" "unprognostic (2.53e-1)" "unprognostic (7.05e-2)" "unprognostic (3.86e-2)" "unprognostic (2.01e-1)" "unprognostic (4.73e-2)" "unprognostic (3.93e-1)" "unprognostic (2.61e-1)" "unprognostic (4.63e-3)" KDR "CD309, FLK1, VEGFR, VEGFR2" ENSG00000128052 "Kinase insert domain receptor" P35968 4 55078481-55125595 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins" "Angiogenesis, Differentiation, Host-virus interaction" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Lymphatic endothelial cells: 240.8;Mesothelial cells: 191.9;Müller glia: 283.5;Vascular endothelial cells: 240.6" "Group enriched" "Detected in many" 4 "endothelial cell: 114.8;fibroblast: 55.5" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 27.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Rhabdoid: 54.8" "Adipose subcutaneous - Endothelial cells, Adrenal gland - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Liver - Sinusoid Endothelial cells, Minor Salivary Gland - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004028, HPA069304, HPA073577" Enhanced Approved "Nuclear membrane,Vesicles,Cytosol,Connecting piece,Mid piece,Principal piece" "Intracellular and membrane" Receptor NA NA 2300000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 5: Rhabdoid - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 44 Vesicles "Nuclear membrane, Cytosol, Connecting piece, Mid piece, Principal piece" "CAB004028: , HPA069304: , HPA073577: " "unprognostic (2.09e-2)" "unprognostic (1.63e-1)" "unprognostic (2.24e-1)" "unprognostic (3.63e-1)" "unprognostic (1.95e-1)" "unprognostic (2.04e-1)" "unprognostic (7.05e-2)" "unprognostic (1.31e-2)" "unprognostic (1.09e-1)" "validated prognostic favorable (5.31e-10)" "validated prognostic favorable (1.73e-5)" "unprognostic (3.65e-3)" "unprognostic (1.16e-2)" "unprognostic (1.62e-3)" "unprognostic (8.98e-2)" "unprognostic (2.02e-3)" "unprognostic (5.90e-2)" "unprognostic (1.76e-2)" "unprognostic (3.31e-2)" "unprognostic (2.51e-2)" "unprognostic (4.01e-2)" "unprognostic (1.07e-1)" "unprognostic (1.30e-1)" "unprognostic (7.48e-2)" "unprognostic (1.26e-1)" "unprognostic (5.11e-2)" "unprognostic (1.17e-1)" "unprognostic (3.01e-2)" "unprognostic (3.72e-1)" "unprognostic (1.09e-3)" KDSR "DHSR, FVT1, SDR35C1" ENSG00000119537 "3-ketodihydrosphingosine reductase" Q06136 18 63327726-63367228 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" Oxidoreductase "Cancer-related genes, Disease variant, Palmoplantar keratoderma, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ocular epithelial cells: 250.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003673, HPA044884" Approved NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 55: Breast - Lactation" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 100: Stratified epithelial cells - Barrier functions" 31 "CAB003673: , HPA044884: " "unprognostic (4.65e-2)" "unprognostic (1.87e-1)" "unprognostic (1.21e-3)" "unprognostic (4.69e-3)" "unprognostic (9.93e-2)" "potential prognostic unfavorable (8.67e-4)" "unprognostic (3.01e-1)" "unprognostic (7.77e-3)" "unprognostic (1.12e-1)" "unprognostic (1.07e-2)" "validated prognostic favorable (8.55e-9)" "validated prognostic favorable (1.35e-5)" "unprognostic (3.16e-2)" "unprognostic (5.55e-2)" "unprognostic (2.22e-2)" "unprognostic (1.15e-1)" "unprognostic (1.27e-1)" "unprognostic (1.72e-2)" "unprognostic (8.35e-2)" "unprognostic (6.08e-2)" "unprognostic (2.61e-2)" "unprognostic (6.89e-2)" "unprognostic (8.11e-2)" "unprognostic (2.08e-1)" "unprognostic (6.72e-2)" "unprognostic (1.39e-1)" "unprognostic (3.11e-1)" "unprognostic (5.60e-2)" "unprognostic (1.02e-1)" "unprognostic (3.43e-2)" "unprognostic (1.76e-1)" KEAP1 "INrf2, KIAA0132, KLHL19, MGC10630, MGC1114, MGC20887, MGC4407, MGC9454" ENSG00000079999 "Kelch like ECH associated protein 1" Q14145 19 10486125-10503558 "Cancer-related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 170.8" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005558, CAB025337" Approved Supported "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 149 "Nucleoplasm, Centriolar satellite" Cytosol "CAB025337: , HPA005558: " "unprognostic (1.54e-1)" "unprognostic (1.96e-1)" "unprognostic (5.85e-2)" "unprognostic (5.35e-3)" "unprognostic (2.62e-1)" "unprognostic (8.63e-2)" "unprognostic (2.78e-1)" "unprognostic (9.79e-2)" "unprognostic (1.86e-2)" "unprognostic (5.96e-3)" "unprognostic (1.32e-1)" "unprognostic (3.46e-2)" "unprognostic (4.45e-2)" "unprognostic (6.61e-3)" "unprognostic (5.93e-3)" "unprognostic (8.08e-2)" "unprognostic (1.17e-1)" "unprognostic (4.36e-2)" "unprognostic (4.04e-3)" "unprognostic (4.29e-3)" "unprognostic (2.90e-1)" "unprognostic (1.40e-1)" "unprognostic (1.46e-1)" "unprognostic (1.15e-1)" "unprognostic (1.84e-1)" "unprognostic (3.13e-1)" "unprognostic (1.13e-1)" "unprognostic (1.77e-2)" "unprognostic (1.64e-1)" "unprognostic (1.34e-1)" "unprognostic (1.20e-2)" KEL "CD238, ECE3" ENSG00000197993 "Kell metallo-endopeptidase (Kell blood group)" P23276 7 142941114-142962363 "Blood group antigen proteins, Cancer-related genes, CD markers, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Blood group antigen, Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 53.1;testis: 36.6" "Group enriched" "Detected in some" 4 "Erythrocyte progenitors: 28.6;Oligodendrocytes: 32.9;Sertoli cells: 22.8" "Cell type enriched" "Detected in many" 5 "oligodendrocyte: 54.7" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 4.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 19 "Leukemia: 10.4" "Colon - Enteric glia cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Sertoli cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA064442 Approved "Nucleoplasm,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 44: Bone marrow - Nuclear processes" "Cluster 6: Non-specific - Immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 80: Oligodendrocytes - Myelination" 8 "Golgi apparatus, Plasma membrane" "Nucleoplasm, Cytosol" "HPA064442: " "unprognostic (9.70e-2)" "unprognostic (2.99e-2)" "potential prognostic favorable (2.19e-4)" "unprognostic (1.98e-2)" "unprognostic (1.49e-2)" "unprognostic (1.35e-2)" "unprognostic (4.43e-2)" "unprognostic (5.55e-2)" "unprognostic (1.52e-1)" KERA "CNA2, SLRR2B" ENSG00000139330 Keratocan O60938 12 91050491-91058024 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Sensory transduction, Vision" "Disease variant" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Fibroblasts: 2.8" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Testicular Germ Cell Tumor (TCGA): 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 3.8;Sarcoma: 13.0" "Skeletal muscle - Fibroblasts" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "amygdala: 5.5;basal ganglia: 7.3;cerebral cortex: 8.2;hippocampal formation: 7.4" HPA039321 Uncertain "Secreted to extracellular matrix" Other NA NA 21000 "Cluster 5: Rhabdoid - Unknown function" "Cluster 108: Fibroblasts - ECM organization" "HPA039321: " "unprognostic (1.77e-1)" "unprognostic (1.18e-1)" "unprognostic (6.00e-3)" KHDC1 "bA257K9.4, C6orf147, C6orf148, Em:AC019205.8, MGC10818, NDG1" ENSG00000135314 "KH domain containing 1" Q4VXA5 6 73241314-73310365 "Predicted intracellular proteins, Predicted membrane proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 14.1" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 50.3;Brain inhibitory neurons: 47.9;Epicardial cells: 72.8;Medullary thymic epithelial cells: 64.8;Oligodendrocyte progenitor cells: 48.2;Retinal ganglion cells: 88.8;Rod photoreceptor cells: 44.5" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 15.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" HPA075996 Approved Vesicles,Cytosol NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 78: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" Cytosol Vesicles "HPA075996: " "unprognostic (9.51e-3)" "potential prognostic unfavorable (8.35e-4)" "unprognostic (3.79e-2)" "unprognostic (4.28e-3)" "unprognostic (1.66e-1)" "unprognostic (2.31e-2)" "unprognostic (5.14e-2)" "unprognostic (7.33e-3)" "unprognostic (9.99e-2)" "unprognostic (9.84e-3)" "unprognostic (2.34e-2)" "unprognostic (7.68e-2)" "unprognostic (8.51e-3)" "unprognostic (2.77e-1)" "unprognostic (3.28e-1)" "unprognostic (3.00e-1)" "unprognostic (1.81e-2)" "unprognostic (1.90e-2)" "unprognostic (2.06e-2)" "unprognostic (3.25e-3)" "unprognostic (3.69e-2)" "unprognostic (7.33e-2)" "unprognostic (1.79e-3)" KHDC1L RP11-257K9.7 ENSG00000256980 "KH domain containing 1 like" Q5JSQ8 6 73223544-73225770 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 4 "brain: 7.2;testis: 5.0" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Bergmann glia: 1.4" "Cancer enriched" "Detected in many" 11 "Testicular Germ Cell Tumor (TCGA): 201.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Esophageal cancer: 6.0;head and neck cancer: 15.6" "Pituitary gland - Gonadotropes, Testis - Late spermatids" HPA075996 Approved Vesicles,Cytosol NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 15: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Neurons - Synaptic function & neurogenesis" Cytosol Vesicles "HPA075996: " "unprognostic (6.68e-3)" "unprognostic (8.93e-2)" "unprognostic (4.08e-2)" "unprognostic (4.49e-1)" "unprognostic (4.29e-2)" "unprognostic (3.00e-2)" "unprognostic (8.40e-3)" "unprognostic (4.12e-1)" "unprognostic (4.57e-2)" "unprognostic (4.34e-3)" "unprognostic (2.14e-1)" "unprognostic (3.91e-1)" "unprognostic (2.42e-2)" KHDC3L "C6orf221, ECAT1" ENSG00000203908 "KH domain containing 3 like, subcortical maternal complex member" Q587J8 6 73362658-73364171 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.3;testis: 1.0" "Cell type enriched" "Detected in single" 93 "Oocytes: 64.5" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 2644 "Testicular Germ Cell Tumor (TCGA): 391.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA043699 Uncertain NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 41: Oocytes - Oogenesis" 2 "HPA043699: " "unprognostic (2.48e-1)" KHDC4 "BLOM7, KIAA0907, SNORA80EHG" ENSG00000132680 "KH domain containing 4, pre-mRNA splicing factor" Q7Z7F0 1 155913045-155934413 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008796 Approved Supported Nucleoplasm NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 64: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 65: Non-specific - Cell growth & division" 4 Nucleoplasm "HPA008796: " "unprognostic (1.25e-1)" "unprognostic (1.33e-1)" "unprognostic (5.40e-2)" "unprognostic (7.01e-3)" "unprognostic (1.37e-1)" "unprognostic (6.23e-3)" "unprognostic (2.37e-3)" "unprognostic (3.81e-2)" "unprognostic (5.44e-2)" "potential prognostic unfavorable (7.60e-5)" "unprognostic (2.13e-1)" "unprognostic (2.27e-2)" "potential prognostic unfavorable (4.23e-5)" "unprognostic (1.35e-1)" "unprognostic (3.67e-2)" "unprognostic (8.97e-3)" "unprognostic (3.78e-2)" "unprognostic (1.40e-1)" "unprognostic (1.46e-1)" "unprognostic (8.87e-2)" "unprognostic (1.93e-3)" "unprognostic (2.76e-3)" "unprognostic (8.68e-3)" "unprognostic (1.24e-1)" "unprognostic (2.43e-2)" "unprognostic (1.94e-1)" "unprognostic (1.74e-1)" "unprognostic (2.02e-1)" "unprognostic (2.73e-3)" KHDRBS1 "FLJ34027, p62, Sam68" ENSG00000121774 "KH RNA binding domain containing, signal transduction associated 1" Q07666 1 32013868-32060850 "Predicted intracellular proteins" "Cell cycle, mRNA processing, Transcription, Transcription regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005355, HPA051280, HPA056813" Supported Enhanced Nucleoplasm NA NA 52000 "Cluster 14: Non-specific - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 15: Non-specific - Protein processing" 119 Nucleoplasm "CAB005355: , HPA051280: , HPA056813: " "unprognostic (3.37e-1)" "unprognostic (2.61e-1)" "unprognostic (1.69e-3)" "unprognostic (2.13e-1)" "unprognostic (1.06e-2)" "unprognostic (8.69e-2)" "unprognostic (9.24e-2)" "unprognostic (1.02e-1)" "unprognostic (2.91e-1)" "potential prognostic unfavorable (3.54e-4)" "potential prognostic favorable (1.53e-6)" "unprognostic (1.18e-2)" "unprognostic (1.59e-2)" "validated prognostic unfavorable (2.79e-5)" "validated prognostic unfavorable (4.24e-4)" "unprognostic (3.24e-3)" "unprognostic (3.88e-3)" "unprognostic (6.03e-2)" "unprognostic (3.14e-1)" "unprognostic (3.56e-1)" "unprognostic (3.10e-1)" "unprognostic (1.20e-2)" "unprognostic (1.53e-1)" "unprognostic (3.10e-2)" "unprognostic (9.16e-2)" "unprognostic (7.27e-2)" "unprognostic (2.98e-2)" "unprognostic (4.06e-1)" "unprognostic (2.54e-1)" "unprognostic (7.90e-2)" "unprognostic (7.49e-3)" KHDRBS2 "MGC26664, SLM-1, SLM1" ENSG00000112232 "KH RNA binding domain containing, signal transduction associated 2" Q5VWX1 6 61679961-62286225 "Predicted intracellular proteins" "mRNA processing, Transcription, Transcription regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.4;retina: 3.7;thyroid gland: 3.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 827.0;B-cells: 372.9;Brain excitatory neurons: 761.9;Brain inhibitory neurons: 717.8;Gonadotrophs: 369.3;Hematopoietic stem cells: 409.5;Lactotrophs: 476.8;Müller glia: 491.9;Oligodendrocyte progenitor cells: 341.0;Other brain neurons: 428.2;Retinal amacrine cells: 342.8;Retinal bipolar cells: 963.4;Retinal ganglion cells: 274.3;Retinal horizontal cells: 452.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in single" "Thyroid Carcinoma (TCGA): 1.7" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 13 "memory B-cell: 5.9;naive B-cell: 6.9;plasmacytoid DC: 1.9" "Group enriched" "Detected in many" 12 "B-cells: 6.9;dendritic cells: 1.9" "Not detected" "Not detected" "Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000500, HPA029392" Supported NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 35: Neurons - Synaptic function & neurogenesis" 57 "HPA000500: , HPA029392: " "unprognostic (2.11e-3)" "unprognostic (1.66e-3)" "unprognostic (4.85e-3)" KHDRBS3 "Etle, etoile, SALP, SLM-2, SLM2, T-STAR" ENSG00000131773 "KH RNA binding domain containing, signal transduction associated 3" O75525 8 135457456-135656722 "Predicted intracellular proteins" "Host-virus interaction, mRNA processing, Transcription, Transcription regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 147.1" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 347.9;Breast lactating cells: 365.9;Early spermatids: 433.2;Late primary spermatocytes: 548.5;Microglia: 873.7;Oligodendrocyte progenitor cells: 831.5;Retinal bipolar cells: 450.4;Schwann cells: 656.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 72.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 13 "eosinophil: 1.2" "Lineage enriched" "Detected in single" 13 "granulocytes: 1.2" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Spleen - Fibroblasts_1, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000275, HPA000500, HPA000981" Enhanced Supported Nucleoplasm NA NA "Cluster 67: Testis - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 35: Neurons - Synaptic function & neurogenesis" 55 Nucleoplasm "HPA000275: , HPA000500: , HPA000981: " "unprognostic (1.02e-1)" "unprognostic (2.19e-1)" "unprognostic (4.49e-2)" "unprognostic (1.59e-1)" "unprognostic (1.94e-1)" "unprognostic (4.38e-3)" "unprognostic (2.94e-1)" "unprognostic (1.11e-3)" "unprognostic (4.06e-1)" "unprognostic (7.00e-3)" "potential prognostic favorable (2.85e-9)" "unprognostic (2.11e-3)" "unprognostic (1.00e-1)" "unprognostic (2.10e-2)" "potential prognostic unfavorable (1.37e-4)" "unprognostic (2.31e-1)" "unprognostic (5.04e-2)" "unprognostic (1.05e-1)" "unprognostic (1.26e-2)" "unprognostic (4.84e-2)" "unprognostic (7.60e-3)" "unprognostic (3.67e-2)" "unprognostic (5.48e-2)" "unprognostic (5.19e-2)" "unprognostic (9.43e-2)" "unprognostic (1.51e-2)" "unprognostic (1.34e-1)" "unprognostic (1.30e-1)" "unprognostic (1.38e-1)" "unprognostic (3.09e-1)" "unprognostic (1.42e-1)" KHK ENSG00000138030 Ketohexokinase P50053 2 27086772-27100762 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 12 "intestine: 119.0;kidney: 101.4;liver: 173.3" "Group enriched" "Detected in many" 7 "Enterocytes: 1660.5;Hepatocytes: 475.9" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 26.7" "Group enriched" "Detected in all" 5 "Kidney Renal Clear Cell Carcinoma (TCGA): 90.4;Kidney Renal Papillary Cell Carcinoma (TCGA): 25.0;Liver Hepatocellular Carcinoma (TCGA): 93.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007040 Enhanced Approved Vesicles,Cytosol NA NA 840000 "Cluster 33: Non-specific - ATP binding" "Cluster 76: Non-specific - Metabolism" "Cluster 37: Neurons - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 1: Enterocytes - Absorption and Digestion" 1 "Vesicles, Cytosol" "HPA007040: " "unprognostic (8.60e-3)" "unprognostic (3.36e-1)" "unprognostic (2.38e-1)" "unprognostic (2.52e-1)" "unprognostic (1.76e-1)" "unprognostic (8.16e-2)" "unprognostic (1.33e-1)" "unprognostic (8.92e-2)" "unprognostic (1.03e-1)" "unprognostic (1.08e-1)" "validated prognostic favorable (7.19e-8)" "validated prognostic favorable (8.22e-4)" "unprognostic (5.91e-2)" "unprognostic (3.16e-3)" "unprognostic (1.62e-2)" "unprognostic (6.94e-2)" "unprognostic (5.40e-2)" "unprognostic (2.31e-3)" "unprognostic (4.25e-2)" "unprognostic (9.99e-2)" "unprognostic (2.32e-2)" "unprognostic (3.05e-1)" "unprognostic (2.13e-1)" "unprognostic (1.36e-1)" "unprognostic (4.66e-2)" "unprognostic (1.12e-1)" "unprognostic (1.02e-1)" "unprognostic (8.44e-3)" "unprognostic (2.69e-1)" "unprognostic (1.04e-1)" "unprognostic (2.30e-1)" KHNYN KIAA0323 ENSG00000100441 "KH and NYN domain containing" O15037 14 24429286-24441843 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 122.8;Epicardial cells: 88.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003402 Uncertain Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 49: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 8 Nucleoplasm "Nuclear membrane, Cytosol" "HPA003402: " "unprognostic (4.12e-2)" "unprognostic (2.41e-1)" "unprognostic (4.60e-2)" "potential prognostic unfavorable (1.32e-4)" "unprognostic (1.28e-1)" "unprognostic (5.16e-2)" "unprognostic (1.32e-2)" "potential prognostic unfavorable (3.55e-5)" "unprognostic (6.64e-2)" "potential prognostic unfavorable (1.12e-4)" "validated prognostic favorable (4.68e-4)" "validated prognostic favorable (7.43e-5)" "unprognostic (1.25e-1)" "unprognostic (3.16e-2)" "unprognostic (2.11e-1)" "unprognostic (2.35e-1)" "unprognostic (1.09e-2)" "unprognostic (1.63e-1)" "unprognostic (2.58e-1)" "unprognostic (1.08e-3)" "unprognostic (2.35e-1)" "unprognostic (1.59e-1)" "unprognostic (1.68e-1)" "unprognostic (1.54e-1)" "unprognostic (4.86e-2)" "unprognostic (1.71e-1)" "unprognostic (2.68e-1)" "unprognostic (1.78e-1)" "unprognostic (1.06e-1)" "unprognostic (2.26e-2)" "unprognostic (7.00e-2)" KHSRP "FBP2, FUBP2, KSRP" ENSG00000088247 "KH-type splicing regulatory protein" Q92945 19 6413102-6424811 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, mRNA transport, Transcription, Transcription regulation, Transport" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034739, HPA056518" Supported Enhanced Nucleoplasm NA NA 21000 "Cluster 30: Non-specific - DNA binding" "Cluster 67: Testis - Mixed function" "Cluster 34: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 26 Nucleoplasm "HPA034739: , HPA056518: " "unprognostic (5.05e-3)" "unprognostic (2.89e-1)" "unprognostic (3.19e-1)" "unprognostic (4.23e-2)" "unprognostic (2.74e-1)" "unprognostic (1.85e-1)" "unprognostic (1.56e-1)" "unprognostic (2.61e-2)" "unprognostic (4.78e-2)" "unprognostic (4.45e-2)" "unprognostic (1.84e-3)" "unprognostic (4.70e-2)" "unprognostic (4.49e-2)" "unprognostic (1.70e-2)" "potential prognostic unfavorable (3.92e-4)" "unprognostic (8.57e-3)" "unprognostic (3.57e-2)" "unprognostic (1.32e-1)" "unprognostic (3.47e-2)" "unprognostic (2.29e-1)" "unprognostic (1.41e-1)" "unprognostic (5.50e-2)" "unprognostic (8.47e-2)" "unprognostic (2.16e-2)" "unprognostic (3.38e-2)" "unprognostic (2.96e-2)" "unprognostic (5.56e-2)" "unprognostic (8.32e-3)" "unprognostic (2.01e-1)" "unprognostic (1.06e-1)" "unprognostic (6.24e-2)" KIAA0040 ENSG00000235750 KIAA0040 Q15053 1 175156986-175192999 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 94.4" "Cell type enhanced" "Detected in many" "Epididymal basal cells: 159.0;Epididymal efferent duct ciliated cells: 140.2;Neutrophils: 342.6;Salivary acinar cells: 144.9;Syncytiotrophoblasts: 585.6;Thymic myoid cells: 212.1" "Cell type enhanced" "Detected in some" "leukocyte: 42.3;pericyte: 30.1;vascular associated smooth muscle cell: 39.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "lymphoma: 58.3" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA016895, HPA068812" Approved Approved Nucleoplasm NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 8: Immune cells - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" Nucleoplasm "HPA016895: , HPA068812: " "unprognostic (1.68e-1)" "unprognostic (1.75e-1)" "unprognostic (5.85e-2)" "potential prognostic unfavorable (4.94e-4)" "unprognostic (1.60e-1)" "unprognostic (2.11e-1)" "unprognostic (1.33e-2)" "unprognostic (1.05e-3)" "unprognostic (1.31e-2)" "unprognostic (2.24e-3)" "validated prognostic favorable (6.13e-5)" "validated prognostic favorable (3.35e-5)" "unprognostic (6.35e-2)" "unprognostic (1.49e-1)" "potential prognostic favorable (2.51e-4)" "unprognostic (8.33e-2)" "unprognostic (2.02e-2)" "unprognostic (1.36e-2)" "unprognostic (3.20e-1)" "unprognostic (8.93e-3)" "potential prognostic unfavorable (8.64e-4)" "unprognostic (1.70e-2)" "unprognostic (1.16e-1)" "unprognostic (2.80e-1)" "unprognostic (1.00e-1)" "unprognostic (1.85e-3)" "unprognostic (1.93e-1)" "unprognostic (1.21e-1)" "unprognostic (1.69e-1)" "unprognostic (4.04e-1)" "unprognostic (1.04e-2)" KIAA0232 ENSG00000170871 KIAA0232 Q92628 4 6781375-6884170 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 686.4;Neutrophils: 929.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 10.6" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "HPA036891, HPA036892, HPA061498" Approved Approved "Cell Junctions,Mitochondria,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 27: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 13 Cytosol "Cell Junctions, Mitochondria" "HPA036891: , HPA036892: , HPA061498: " "unprognostic (1.34e-2)" "unprognostic (3.45e-2)" "unprognostic (3.86e-2)" "unprognostic (1.83e-1)" "unprognostic (8.61e-3)" "unprognostic (3.09e-2)" "unprognostic (2.23e-1)" "unprognostic (1.25e-1)" "unprognostic (8.05e-2)" "unprognostic (3.30e-3)" "validated prognostic favorable (1.41e-6)" "validated prognostic favorable (9.39e-4)" "unprognostic (2.52e-2)" "unprognostic (1.40e-1)" "unprognostic (3.70e-1)" "unprognostic (3.14e-1)" "unprognostic (1.73e-1)" "unprognostic (2.65e-2)" "unprognostic (6.75e-2)" "unprognostic (2.32e-1)" "unprognostic (9.42e-2)" "unprognostic (1.23e-2)" "unprognostic (9.03e-2)" "unprognostic (1.89e-1)" "unprognostic (1.29e-1)" "unprognostic (1.38e-1)" "unprognostic (2.09e-1)" "unprognostic (2.73e-2)" "unprognostic (7.52e-2)" "unprognostic (1.53e-1)" "unprognostic (4.20e-2)" KIAA0319 NMIG ENSG00000137261 KIAA0319 Q5VV43 6 24544104-24646191 "Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Neurogenesis "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 11.2;pituitary gland: 3.9" "Cell type enhanced" "Detected in many" "Astrocytes: 190.9;Brain excitatory neurons: 157.5;Brain inhibitory neurons: 102.8;Corticotrophs: 140.4;Early spermatids: 121.3;Ependymal cells: 277.2;Lactotrophs: 85.9;Late spermatids: 153.1;Neutrophils: 149.8;Other brain neurons: 154.2;Pancreatic islet cells: 91.4;Respiratory ciliated cells: 240.2;Somatotrophs: 111.7;Thyrotrophs: 183.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.6" "Lineage enhanced" "Detected in single" "granulocytes: 1.6" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Spleen - Neutrophils_2, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015607, HPA076313" Enhanced Supported Approved Vesicles "Secreted in brain" "Developmental protein" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 109: Neurons - Neuronal signaling" Vesicles "HPA015607: , HPA076313: " "unprognostic (7.62e-2)" "unprognostic (9.61e-3)" "unprognostic (5.34e-2)" "unprognostic (8.98e-2)" "unprognostic (3.64e-1)" "unprognostic (3.99e-3)" "unprognostic (2.87e-1)" "unprognostic (2.78e-1)" "unprognostic (2.64e-2)" "unprognostic (2.11e-3)" "unprognostic (7.01e-2)" "unprognostic (1.51e-2)" KIAA0319L "AAVR, KIAA1837" ENSG00000142687 "KIAA0319 like" Q8IZA0 1 35393883-35557950 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072692 Supported Supported "Nucleoli,Golgi apparatus" NA NA 370000 "Cluster 28: Neutrophils - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 38: Sub-cortical - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 6 "Golgi apparatus" Nucleoli "HPA072692: " "unprognostic (9.17e-2)" "unprognostic (2.15e-1)" "unprognostic (2.96e-1)" "unprognostic (3.86e-3)" "unprognostic (1.05e-3)" "unprognostic (2.30e-1)" "unprognostic (4.57e-2)" "unprognostic (1.18e-1)" "unprognostic (2.35e-1)" "unprognostic (1.13e-1)" "potential prognostic favorable (5.92e-6)" "unprognostic (8.88e-2)" "unprognostic (6.22e-2)" "potential prognostic unfavorable (1.18e-5)" "unprognostic (7.12e-2)" "unprognostic (7.17e-2)" "unprognostic (1.69e-2)" "unprognostic (1.05e-1)" "unprognostic (2.64e-1)" "unprognostic (4.47e-2)" "unprognostic (2.88e-1)" "unprognostic (9.33e-2)" "unprognostic (3.84e-1)" "unprognostic (2.27e-1)" "unprognostic (3.35e-1)" "unprognostic (5.68e-3)" "unprognostic (9.35e-2)" "unprognostic (1.86e-1)" "unprognostic (1.95e-1)" "unprognostic (2.57e-1)" "unprognostic (1.03e-1)" KIAA0408 ENSG00000189367 KIAA0408 Q6ZU52 6 127438406-127459389 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.6;skeletal muscle: 26.4" "Cell type enhanced" "Detected in some" "Astrocytes: 7.8;Bergmann glia: 29.4;Brain excitatory neurons: 45.1;Brain inhibitory neurons: 43.4;Ependymal cells: 7.9;Myosatellite cells: 17.7;Oligodendrocyte progenitor cells: 24.6;Oligodendrocytes: 15.7;Other brain neurons: 39.6" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 8.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "Neuroblastoma: 30.0" "Liver - Hepatic stellate cells, Lung - Alveolar cells type 1, Prostate - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044035, HPA053341" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 34: Non-specific - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 26 Nucleoplasm Cytosol "HPA044035: , HPA053341: " "unprognostic (6.96e-2)" "unprognostic (2.50e-3)" "unprognostic (5.59e-2)" "unprognostic (1.82e-2)" "potential prognostic favorable (9.39e-4)" "unprognostic (1.04e-2)" "unprognostic (1.46e-2)" "unprognostic (1.17e-3)" "unprognostic (1.78e-1)" "unprognostic (6.74e-2)" "unprognostic (2.54e-2)" "unprognostic (3.82e-3)" "unprognostic (3.41e-2)" KIAA0513 ENSG00000135709 KIAA0513 O60268 16 85027782-85094230 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 54.3" "Cell type enhanced" "Detected in many" "Lactotrophs: 142.2;Late spermatids: 455.7;Neutrophil progenitors: 119.9;Neutrophils: 134.2;Platelets: 400.9;Somatotrophs: 175.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "granulocytes: 25.1;monocytes: 23.5" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Skin - Keratinocyte (granular), Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012866, HPA014431" Enhanced Approved Cytosol NA NA 33000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 48: Neutrophils - Phagocytosis & degranulation" Cytosol "HPA012866: , HPA014431: " "unprognostic (3.59e-3)" "unprognostic (7.16e-3)" "unprognostic (5.42e-3)" "unprognostic (1.80e-1)" "unprognostic (1.18e-1)" "unprognostic (6.78e-2)" "unprognostic (1.09e-1)" "unprognostic (1.63e-2)" "unprognostic (2.80e-3)" "unprognostic (4.21e-3)" "unprognostic (4.43e-3)" "unprognostic (4.99e-2)" "unprognostic (3.03e-2)" "unprognostic (9.46e-3)" "unprognostic (1.20e-1)" "unprognostic (3.38e-2)" "unprognostic (8.72e-2)" "unprognostic (1.55e-1)" "unprognostic (5.00e-2)" "unprognostic (1.88e-1)" "unprognostic (3.23e-2)" "unprognostic (5.33e-3)" "unprognostic (3.46e-2)" "unprognostic (1.26e-1)" "unprognostic (2.64e-1)" "unprognostic (1.33e-1)" "unprognostic (1.80e-1)" "unprognostic (9.00e-2)" "unprognostic (8.82e-2)" "unprognostic (5.59e-3)" "unprognostic (3.94e-2)" KIAA0586 "JBTS23, Talpid3" ENSG00000100578 KIAA0586 Q9BVV6 14 58427385-58551297 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 203.3;Late spermatids: 190.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000846 Uncertain NA NA "Cluster 24: Non-specific - Transcription" "Cluster 39: Testis - Nuclear processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 7: Non-specific - Transcription" 3 "HPA000846: " "unprognostic (3.80e-1)" "unprognostic (6.49e-2)" "unprognostic (3.01e-1)" "unprognostic (3.17e-1)" "unprognostic (1.58e-2)" "unprognostic (1.91e-1)" "unprognostic (1.17e-1)" "unprognostic (3.37e-2)" "unprognostic (8.83e-2)" "unprognostic (2.73e-3)" "potential prognostic favorable (5.49e-4)" "unprognostic (2.35e-3)" "unprognostic (3.95e-2)" "unprognostic (2.25e-2)" "unprognostic (2.25e-1)" "unprognostic (2.36e-3)" "unprognostic (1.51e-2)" "unprognostic (2.09e-2)" "unprognostic (1.04e-1)" "unprognostic (1.65e-1)" "unprognostic (1.05e-1)" "unprognostic (1.02e-1)" "unprognostic (8.21e-2)" "unprognostic (3.61e-1)" "unprognostic (9.40e-2)" "unprognostic (8.00e-2)" "unprognostic (1.03e-1)" "unprognostic (2.16e-2)" "unprognostic (3.05e-1)" "unprognostic (1.01e-1)" "unprognostic (6.46e-2)" KIAA0753 "MNR, OFIP" ENSG00000198920 KIAA0753 Q2KHM9 17 6578147-6640711 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant, Joubert syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 122.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Spleen - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" "HPA023057, HPA023494" Enhanced Supported "Primary cilium,Centrosome,Basal body,Cytosol" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 21: Testis - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 48 Centrosome "Primary cilium, Basal body, Cytosol" "HPA023057: , HPA023494: " "unprognostic (8.92e-2)" "unprognostic (9.25e-3)" "unprognostic (2.06e-1)" "unprognostic (4.21e-3)" "unprognostic (1.08e-2)" "unprognostic (4.42e-2)" "unprognostic (3.76e-1)" "unprognostic (2.58e-2)" "unprognostic (5.07e-2)" "unprognostic (2.48e-2)" "unprognostic (1.42e-1)" "unprognostic (3.30e-3)" "unprognostic (8.72e-2)" "potential prognostic unfavorable (8.44e-4)" "unprognostic (6.92e-2)" "unprognostic (1.07e-1)" "unprognostic (2.14e-1)" "unprognostic (4.16e-1)" "unprognostic (3.43e-2)" "unprognostic (1.82e-1)" "unprognostic (4.20e-1)" "unprognostic (5.47e-2)" "unprognostic (3.48e-3)" "unprognostic (7.71e-3)" "unprognostic (1.79e-2)" "unprognostic (1.37e-2)" "unprognostic (6.99e-3)" "unprognostic (3.14e-1)" "unprognostic (2.72e-1)" "unprognostic (9.29e-3)" "unprognostic (3.59e-1)" KIAA0825 "C5orf36, DKFZp686F0372, MGC34713" ENSG00000185261 KIAA0825 Q8IV33 5 94150851-94618604 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 612.8;Ependymal cells: 1262.9;Lactotrophs: 447.8;Neutrophil progenitors: 474.8;Neutrophils: 2010.0;Respiratory ciliated cells: 825.1" "Cell type enhanced" "Detected in all" "ependymal cell: 1321.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "neutrophil: 11.8" "Lineage enriched" "Detected in single" 12 "granulocytes: 11.8" "Low cancer specificity" "Detected in some" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038030, HPA038031" Uncertain NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 5: Rhabdoid - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" 3 "HPA038030: , HPA038031: " "unprognostic (7.51e-2)" "unprognostic (2.38e-1)" "unprognostic (9.37e-2)" "unprognostic (5.58e-2)" "potential prognostic favorable (6.99e-9)" "unprognostic (4.30e-2)" "unprognostic (3.56e-2)" "unprognostic (2.69e-1)" "unprognostic (4.24e-1)" "unprognostic (1.03e-2)" "unprognostic (5.21e-2)" "unprognostic (1.25e-3)" KIAA0930 "bK268H5.C22.1, C22orf9" ENSG00000100364 KIAA0930 Q6ICG6 22 45192244-45240894 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 183.3" "Cell type enhanced" "Detected in many" "Astrocytes: 261.2;Brain excitatory neurons: 112.9;Erythrocyte progenitors: 110.7;Monocyte progenitors: 151.5;Oligodendrocytes: 251.7;Other brain neurons: 130.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 11.0;eosinophil: 8.6;intermediate monocyte: 13.9;myeloid DC: 12.1;non-classical monocyte: 17.4;plasmacytoid DC: 10.1" "Group enriched" "Detected in all" 5 "dendritic cells: 12.1;granulocytes: 8.6;monocytes: 17.4" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038091 Uncertain Approved "Nucleoplasm,Nuclear membrane,Mitochondria" No No "Cluster 29: Non-specific - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 35: Neurons - Synaptic function & neurogenesis" 22 "Nuclear membrane, Mitochondria" Nucleoplasm "HPA038091: " "unprognostic (2.28e-2)" "unprognostic (2.00e-1)" "unprognostic (3.52e-2)" "unprognostic (7.03e-2)" "unprognostic (1.72e-2)" "unprognostic (3.04e-2)" "unprognostic (4.51e-2)" "unprognostic (1.23e-1)" "unprognostic (2.01e-1)" "unprognostic (1.93e-3)" "unprognostic (1.66e-1)" "unprognostic (1.01e-1)" "potential prognostic unfavorable (3.06e-7)" "unprognostic (1.46e-3)" "unprognostic (2.05e-1)" "unprognostic (2.71e-1)" "unprognostic (7.69e-2)" "unprognostic (1.85e-2)" "unprognostic (5.99e-3)" "unprognostic (1.13e-1)" "unprognostic (2.32e-1)" "unprognostic (2.65e-1)" "unprognostic (1.77e-1)" "unprognostic (1.95e-1)" "unprognostic (2.06e-2)" "unprognostic (4.50e-1)" "unprognostic (1.11e-1)" "unprognostic (6.66e-2)" "unprognostic (7.03e-3)" "unprognostic (2.91e-2)" KIAA1143 ENSG00000163807 KIAA1143 Q96AT1 3 44737661-44761619 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 7 "Early spermatids: 198.6;Late primary spermatocytes: 82.1;Late spermatids: 66.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045018, HPA061799" Approved Enhanced "Nucleoplasm,Cytokinetic bridge" Yes No "Cluster 16: Non-specific - Cell proliferation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 5 Nucleoplasm "Cytokinetic bridge" "HPA045018: , HPA061799: " "potential prognostic favorable (2.24e-5)" "unprognostic (8.54e-2)" "unprognostic (3.77e-1)" "unprognostic (1.00e-1)" "unprognostic (1.62e-1)" "unprognostic (8.04e-2)" "unprognostic (5.20e-1)" "unprognostic (5.03e-2)" "unprognostic (2.71e-3)" "potential prognostic unfavorable (6.17e-5)" "potential prognostic favorable (1.35e-6)" "unprognostic (6.92e-3)" "unprognostic (3.85e-2)" "unprognostic (6.20e-3)" "unprognostic (1.00e-1)" "unprognostic (2.27e-1)" "unprognostic (1.34e-1)" "unprognostic (2.08e-1)" "unprognostic (9.34e-2)" "unprognostic (3.94e-1)" "unprognostic (1.25e-2)" "unprognostic (2.63e-1)" "unprognostic (4.31e-2)" "unprognostic (4.51e-2)" "unprognostic (4.95e-3)" "unprognostic (7.70e-3)" "unprognostic (1.85e-1)" "unprognostic (1.84e-1)" "unprognostic (1.74e-1)" "unprognostic (1.36e-2)" "unprognostic (4.20e-3)" KIAA1191 "FLJ21022, p33MONOX, p60MONOX" ENSG00000122203 KIAA1191 Q96A73 5 176346062-176361807 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 152.9;Parietal cells: 325.3;Platelets: 129.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Spleen - Endothelial cells, Stomach - Parietal cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044701, HPA048145" Uncertain Approved Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 72: Kidney - Transmembrane transport" "Cluster 14: Neurons - Synaptic function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 97: Non-specific - Cellular respiration" 4 Nucleoplasm "HPA044701: , HPA048145: " "unprognostic (8.24e-2)" "unprognostic (1.85e-2)" "unprognostic (1.75e-1)" "unprognostic (1.51e-3)" "unprognostic (1.46e-1)" "unprognostic (1.05e-3)" "unprognostic (8.39e-2)" "unprognostic (1.43e-3)" "unprognostic (1.72e-1)" "unprognostic (1.58e-3)" "potential prognostic favorable (1.19e-11)" "unprognostic (1.57e-3)" "unprognostic (1.10e-1)" "unprognostic (4.00e-1)" "unprognostic (1.02e-1)" "unprognostic (1.52e-1)" "unprognostic (2.64e-1)" "unprognostic (1.13e-2)" "unprognostic (1.45e-1)" "unprognostic (3.41e-1)" "unprognostic (2.16e-2)" "unprognostic (5.19e-2)" "unprognostic (1.15e-1)" "unprognostic (4.86e-2)" "unprognostic (1.59e-2)" "unprognostic (9.16e-2)" "unprognostic (2.24e-1)" "unprognostic (7.81e-2)" "unprognostic (7.42e-2)" "unprognostic (3.25e-2)" "unprognostic (1.88e-1)" KIAA1210 ENSG00000250423 KIAA1210 Q9ULL0 X 119078635-119150579 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "epididymis: 39.4;seminal vesicle: 19.7;testis: 30.6" "Cell type enriched" "Detected in some" 8 "Sertoli cells: 218.5" "Cell type enriched" "Detected in single" 6 "fibroblast: 3.5" "Cancer enhanced" "Detected in some" "Prostate Adenocarcinoma (TCGA): 1.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Sertoli cells" "Not detected" "Not detected" "HPA000551, HPA048322" Enhanced Approved "Golgi apparatus,Vesicles" NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" "Golgi apparatus, Vesicles" "HPA000551: , HPA048322: " "unprognostic (1.09e-1)" "unprognostic (3.80e-2)" KIAA1217 "DKFZP761L0424, ETL4, SKT" ENSG00000120549 KIAA1217 Q5T5P2 10 23694746-24547848 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 101.4" "Cell type enhanced" "Detected in many" "Müller glia: 2401.3;Myonuclei: 3977.9;Thymic myoid cells: 4225.7" "Cell type enhanced" "Detected in all" "deep-layer corticothalamic and 6b: 4060.3;MGE interneuron: 3064.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Colon - Enteric glia cells, Prostate - Prostate basal glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004941 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 1: T-cells - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 6 "Nucleoplasm, Cytosol" "HPA004941: " "unprognostic (5.30e-2)" "unprognostic (4.37e-2)" "unprognostic (3.04e-1)" "unprognostic (4.62e-3)" "unprognostic (6.79e-2)" "unprognostic (2.90e-2)" "unprognostic (1.62e-1)" "unprognostic (2.72e-1)" "unprognostic (2.44e-3)" "unprognostic (2.22e-1)" "validated prognostic favorable (2.34e-5)" "validated prognostic favorable (4.28e-5)" "unprognostic (3.88e-1)" "potential prognostic unfavorable (8.58e-4)" "unprognostic (3.49e-1)" "unprognostic (1.75e-2)" "unprognostic (2.18e-2)" "unprognostic (9.95e-2)" "unprognostic (3.02e-1)" "unprognostic (3.01e-2)" "unprognostic (4.23e-3)" "unprognostic (1.45e-2)" "unprognostic (1.11e-1)" "unprognostic (2.60e-1)" "unprognostic (1.87e-1)" "unprognostic (1.10e-1)" "unprognostic (1.96e-2)" "unprognostic (1.90e-1)" "unprognostic (2.08e-1)" "unprognostic (1.38e-1)" "unprognostic (2.17e-1)" KIAA1328 ENSG00000150477 KIAA1328 Q86T90 18 36829106-37232172 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 630.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatic stellate cells, Lung - Fibroblasts_1, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040946, HPA048201" Approved Approved "Nuclear speckles,Vesicles,Lipid droplets,Plasma membrane" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 40: Non-specific - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 56: Non-specific - Sensory perception" "Cluster 7: Non-specific - Transcription" 34 "Nuclear speckles" "Vesicles, Lipid droplets, Plasma membrane" "HPA040946: , HPA048201: " "unprognostic (2.79e-1)" "unprognostic (7.50e-2)" "unprognostic (3.34e-1)" "unprognostic (4.39e-2)" "unprognostic (1.87e-3)" "unprognostic (1.20e-1)" "unprognostic (9.09e-2)" "unprognostic (4.17e-2)" "unprognostic (1.48e-1)" "unprognostic (7.01e-2)" "unprognostic (7.70e-2)" "unprognostic (2.33e-3)" "unprognostic (2.35e-1)" "unprognostic (9.86e-2)" "unprognostic (1.51e-2)" "unprognostic (2.39e-1)" "unprognostic (2.47e-2)" "unprognostic (1.03e-1)" "unprognostic (4.44e-2)" "unprognostic (7.45e-2)" "unprognostic (3.08e-1)" "unprognostic (1.99e-2)" "unprognostic (1.44e-2)" "unprognostic (9.57e-2)" "unprognostic (2.80e-2)" "unprognostic (1.26e-2)" "unprognostic (4.77e-1)" "unprognostic (2.50e-1)" "unprognostic (1.80e-1)" "unprognostic (1.61e-2)" "unprognostic (1.35e-1)" KIAA1522 ENSG00000162522 KIAA1522 Q9P206 1 32741830-32774970 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 78.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Skin - Keratinocyte (granular), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032050, HPA032051, HPA064839" Approved Supported "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 60: Stomach - Digestion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 28 "Plasma membrane, Cell Junctions" Nucleoplasm "HPA032050: , HPA032051: , HPA064839: " "unprognostic (2.85e-2)" "unprognostic (1.35e-1)" "unprognostic (4.87e-1)" "unprognostic (3.46e-2)" "unprognostic (6.35e-2)" "unprognostic (1.48e-2)" "unprognostic (1.85e-1)" "unprognostic (4.77e-2)" "unprognostic (2.53e-2)" "unprognostic (6.75e-2)" "potential prognostic favorable (9.29e-4)" "unprognostic (1.20e-2)" "unprognostic (2.92e-2)" "validated prognostic unfavorable (4.78e-6)" "validated prognostic unfavorable (1.17e-4)" "unprognostic (1.79e-2)" "unprognostic (2.78e-2)" "unprognostic (1.58e-1)" "unprognostic (3.13e-1)" "unprognostic (8.60e-2)" "unprognostic (6.14e-2)" "potential prognostic unfavorable (3.67e-4)" "unprognostic (7.60e-2)" "unprognostic (8.56e-2)" "unprognostic (2.82e-2)" "unprognostic (3.98e-2)" "unprognostic (4.12e-2)" "unprognostic (3.35e-2)" "unprognostic (2.64e-1)" "unprognostic (2.08e-1)" "unprognostic (2.79e-1)" KIAA1549 ENSG00000122778 KIAA1549 Q9HCM3 7 138831381-138981389 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Mast cells: 420.7;Proximal tubule cells: 318.7;Renal collecting duct principal cells: 114.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Neuroblastoma: 20.4" "Minor Salivary Gland - Smooth muscle cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019560 Uncertain Approved "Nuclear membrane,Intermediate filaments" NA NA 19000 "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 58: Mast cells - Allergic inflammatory responses" 4 "Nuclear membrane" "Intermediate filaments" "HPA019560: " "unprognostic (1.71e-1)" "unprognostic (4.18e-2)" "unprognostic (1.43e-1)" "unprognostic (1.33e-2)" "unprognostic (2.90e-2)" "unprognostic (1.12e-2)" "unprognostic (1.99e-1)" "unprognostic (5.84e-3)" "unprognostic (4.52e-2)" "potential prognostic favorable (1.06e-8)" "unprognostic (2.17e-2)" "unprognostic (4.94e-2)" "unprognostic (1.34e-2)" "unprognostic (1.61e-1)" "unprognostic (5.30e-1)" "unprognostic (6.55e-3)" "unprognostic (1.53e-2)" "unprognostic (2.27e-1)" "unprognostic (7.46e-2)" "unprognostic (1.97e-1)" "unprognostic (1.22e-1)" "unprognostic (2.08e-1)" "unprognostic (8.34e-2)" "unprognostic (7.91e-2)" "unprognostic (2.69e-1)" "unprognostic (4.39e-1)" "unprognostic (3.28e-1)" "unprognostic (1.38e-1)" KIAA1549L "C11orf41, C11orf69, G2, MGC34830" ENSG00000110427 "KIAA1549 like" Q6ZVL6 11 33376108-33674102 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "brain: 20.8;parathyroid gland: 30.9" "Cell type enhanced" "Detected in many" "Bergmann glia: 278.0;Brain excitatory neurons: 284.1;Brain inhibitory neurons: 297.4;Ependymal cells: 157.7;Gonadotrophs: 152.3;Melanocytes: 218.6;Oligodendrocyte progenitor cells: 75.5;Other brain neurons: 156.1;Pancreatic islet cells: 82.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 8.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010132, HPA051594" Approved Nucleoplasm,Vesicles NA NA 20000 "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" Nucleoplasm Vesicles "HPA010132: , HPA051594: " "unprognostic (2.92e-1)" "unprognostic (4.28e-1)" "unprognostic (2.39e-1)" "unprognostic (2.64e-1)" "unprognostic (9.68e-3)" "unprognostic (6.15e-2)" "unprognostic (8.66e-2)" "unprognostic (4.45e-1)" "unprognostic (5.88e-2)" "potential prognostic unfavorable (7.72e-4)" "unprognostic (1.81e-2)" "unprognostic (9.08e-2)" "unprognostic (3.62e-3)" "unprognostic (2.01e-2)" KIAA1586 ENSG00000168116 KIAA1586 Q9HCI6 6 57046532-57055239 "Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 135.0;Erythrocyte progenitors: 80.2;Platelets: 72.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" HPA036370 Approved Approved "Nucleoplasm,Nuclear membrane" No No "Cluster 3: Non-specific - Nuclear processes" "Cluster 61: Non-specific - Transcription" "Cluster 2: Neurons - Nucleosome" "Cluster 47: Leukemia - Hemostasis" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" "Nucleoplasm, Nuclear membrane" "HPA036370: " "unprognostic (3.36e-2)" "unprognostic (1.87e-1)" "unprognostic (2.34e-1)" "unprognostic (3.73e-2)" "unprognostic (9.86e-2)" "unprognostic (1.74e-1)" "unprognostic (2.48e-2)" "unprognostic (1.48e-2)" "unprognostic (1.52e-1)" "unprognostic (3.29e-3)" "unprognostic (2.04e-3)" "unprognostic (4.91e-3)" "unprognostic (1.72e-1)" "unprognostic (1.78e-2)" "unprognostic (8.10e-3)" "unprognostic (1.84e-1)" "unprognostic (7.59e-2)" "unprognostic (3.05e-1)" "unprognostic (1.78e-1)" "unprognostic (6.82e-2)" "unprognostic (8.80e-2)" "unprognostic (6.43e-2)" "unprognostic (1.07e-3)" "unprognostic (4.26e-2)" "unprognostic (1.05e-1)" "unprognostic (5.68e-2)" "unprognostic (1.70e-3)" "unprognostic (1.83e-2)" "unprognostic (1.26e-1)" "unprognostic (1.45e-2)" "unprognostic (6.30e-2)" KIAA1614 ENSG00000135835 KIAA1614 Q5VZ46 1 180912897-180951614 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 27.3" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 31.9;Cone photoreceptor cells: 95.2;Distal convoluted tubule cells: 30.0;Retinal bipolar cells: 77.2;Retinal ganglion cells: 34.8;Retinal pigment epithelial cells: 46.9;Rod photoreceptor cells: 139.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Lineage enriched" "Detected in single" 7 "granulocytes: 1.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028227, HPA061684" Approved Approved "Nuclear membrane,Vesicles" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 2: Neurons - Nucleosome" "Cluster 1: Neuronal - Visual perception" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "Nuclear membrane, Vesicles" "HPA028227: , HPA061684: " "unprognostic (1.26e-1)" "unprognostic (1.41e-1)" "unprognostic (9.41e-2)" "unprognostic (2.34e-1)" "unprognostic (1.16e-1)" "unprognostic (2.34e-1)" "unprognostic (4.24e-2)" "potential prognostic unfavorable (3.26e-4)" "unprognostic (4.37e-2)" "unprognostic (3.28e-2)" "validated prognostic favorable (5.53e-7)" "validated prognostic favorable (4.12e-4)" "unprognostic (4.20e-3)" "unprognostic (3.10e-3)" "unprognostic (1.33e-1)" "unprognostic (1.07e-1)" "unprognostic (1.38e-1)" "unprognostic (2.95e-1)" "unprognostic (3.50e-1)" "unprognostic (1.18e-1)" "unprognostic (1.15e-1)" "unprognostic (5.86e-2)" "unprognostic (6.65e-2)" "unprognostic (4.13e-1)" "potential prognostic favorable (1.27e-6)" "unprognostic (5.48e-2)" "unprognostic (5.65e-2)" "unprognostic (9.98e-2)" "unprognostic (4.24e-3)" "unprognostic (5.30e-2)" KIAA1671 ENSG00000197077 KIAA1671 Q9BY89 22 24952716-25197448 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Colonocytes: 387.3;Enterocytes: 377.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 1.8" "Lineage enriched" "Detected in single" 4 "T-cells: 1.8" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018135 Approved Supported "Microtubules,Cytokinetic bridge,Primary cilium" Yes NA "Cluster 1: T-cells - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 29: Forebrain - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 31 "Microtubules, Primary cilium" "Cytokinetic bridge" "HPA018135: " "unprognostic (7.57e-3)" "unprognostic (5.18e-2)" "unprognostic (4.41e-1)" "unprognostic (3.82e-3)" "unprognostic (3.05e-2)" "unprognostic (9.76e-2)" "unprognostic (7.95e-2)" "unprognostic (5.59e-2)" "unprognostic (2.03e-1)" "unprognostic (2.68e-1)" "validated prognostic favorable (7.06e-9)" "validated prognostic favorable (3.39e-5)" "potential prognostic favorable (5.68e-4)" "unprognostic (2.36e-2)" "unprognostic (1.23e-1)" "unprognostic (4.36e-2)" "unprognostic (1.35e-3)" "unprognostic (1.57e-2)" "unprognostic (2.08e-2)" "unprognostic (2.38e-1)" "unprognostic (1.81e-2)" "unprognostic (5.59e-2)" "unprognostic (7.04e-2)" "unprognostic (1.29e-1)" "unprognostic (2.28e-3)" "unprognostic (3.19e-2)" "unprognostic (1.64e-1)" "unprognostic (2.97e-1)" "unprognostic (4.85e-1)" "unprognostic (1.17e-1)" "unprognostic (1.37e-2)" KIAA1755 "quo, RP5-1054A22.3" ENSG00000149633 KIAA1755 Q5JYT7 20 38210503-38260772 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 122.7;Bergmann glia: 131.8;Ependymal cells: 41.4;Fibro-adipogenic progenitors: 88.5;Fibroblasts: 42.0;Oligodendrocytes: 191.1;Peritubular myoid cells: 29.9;Schwann cells: 37.2" "Cell type enhanced" "Detected in many" "astrocyte: 166.6;fibroblast: 470.3;oligodendrocyte: 234.2" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 28.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 9 "Brain cancer: 18.2;Sarcoma: 12.2;skin cancer: 25.2" "Lung - Fibroblasts_2, Minor Salivary Gland - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA051064 Approved Approved "Nucleoli,Golgi apparatus,Vesicles" NA NA "Cluster 65: Brain - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 80: Oligodendrocytes - Myelination" Nucleoli "Golgi apparatus, Vesicles" "HPA051064: " "unprognostic (5.32e-2)" "unprognostic (5.88e-3)" "unprognostic (1.77e-1)" "unprognostic (1.25e-1)" "unprognostic (2.69e-1)" "unprognostic (5.02e-2)" "unprognostic (3.55e-1)" "unprognostic (2.51e-1)" "unprognostic (2.30e-1)" "unprognostic (5.05e-3)" "potential prognostic unfavorable (5.77e-4)" "unprognostic (1.11e-1)" "unprognostic (1.86e-1)" "unprognostic (8.52e-2)" "unprognostic (6.39e-2)" "potential prognostic unfavorable (4.25e-4)" "potential prognostic unfavorable (2.28e-4)" "unprognostic (1.92e-1)" "unprognostic (3.16e-1)" "unprognostic (1.19e-1)" "unprognostic (1.70e-1)" "unprognostic (2.83e-2)" "unprognostic (8.01e-2)" "unprognostic (2.04e-3)" "unprognostic (8.46e-2)" "unprognostic (2.91e-3)" KIAA1958 FLJ39294 ENSG00000165185 KIAA1958 Q8N8K9 9 112486827-112669397 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 735.4;Bergmann glia: 373.9;Distal convoluted tubule cells: 383.7;Sertoli cells: 704.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Stomach - Chief cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020625 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 61: Non-specific - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 18: Adrenal cortex cells - Steroidogensis" 11 "Plasma membrane, Cytosol" "HPA020625: " "unprognostic (1.27e-1)" "unprognostic (4.95e-3)" "unprognostic (2.35e-1)" "unprognostic (3.27e-1)" "unprognostic (1.53e-1)" "unprognostic (2.85e-2)" "unprognostic (5.10e-2)" "unprognostic (7.29e-2)" "unprognostic (1.06e-2)" "unprognostic (4.49e-2)" "validated prognostic favorable (1.47e-6)" "validated prognostic favorable (3.59e-5)" "unprognostic (1.75e-1)" "unprognostic (1.70e-1)" "unprognostic (1.75e-1)" "unprognostic (2.43e-2)" "unprognostic (5.10e-1)" "unprognostic (4.02e-1)" "unprognostic (1.07e-2)" "unprognostic (9.37e-2)" "unprognostic (2.71e-1)" "unprognostic (1.53e-1)" "unprognostic (8.41e-2)" "unprognostic (3.40e-2)" "potential prognostic favorable (9.53e-5)" "unprognostic (2.07e-2)" "unprognostic (7.63e-2)" "unprognostic (8.93e-2)" "unprognostic (3.69e-1)" "unprognostic (3.56e-2)" "unprognostic (1.30e-1)" KIAA2012 ENSG00000182329 KIAA2012 2 202073255-202205188 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "fallopian tube: 8.7" "Cell type enhanced" "Detected in many" "Corticotrophs: 98.8;Early spermatids: 76.6;Endometrial ciliated cells: 77.7;Ependymal cells: 770.3;Epididymal efferent duct ciliated cells: 171.2;Fallopian tube ciliated cells: 290.1;Respiratory ciliated cells: 495.9" "Cell type enriched" "Detected in many" 7 "ependymal cell: 835.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Skin - Outer root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077834 Enhanced NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 11: Neuronal - Sensory perception" "Cluster 34: Ciliated cells - Cilia assembly & function" "HPA077834: " KIAA2013 "MGC33867, RP5-1077B9.1" ENSG00000116685 KIAA2013 Q8IYS2 1 11919591-11926428 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 127.5;Epididymal principal cells: 145.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052677, HPA060536" Uncertain Approved "Golgi apparatus,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 77: Intestine - Digestion" "Cluster 27: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 4 "Golgi apparatus" Cytosol "HPA052677: , HPA060536: " "unprognostic (1.46e-2)" "unprognostic (6.87e-2)" "unprognostic (6.70e-2)" "unprognostic (7.15e-2)" "unprognostic (9.32e-3)" "unprognostic (2.33e-1)" "unprognostic (2.65e-1)" "unprognostic (2.24e-1)" "unprognostic (5.61e-3)" "unprognostic (2.22e-1)" "potential prognostic favorable (3.65e-5)" "unprognostic (3.38e-3)" "unprognostic (1.42e-1)" "validated prognostic unfavorable (2.90e-4)" "validated prognostic unfavorable (6.97e-4)" "unprognostic (3.66e-1)" "unprognostic (9.52e-2)" "unprognostic (1.30e-1)" "unprognostic (1.60e-1)" "unprognostic (6.69e-2)" "unprognostic (2.78e-1)" "unprognostic (3.69e-1)" "unprognostic (4.40e-2)" "unprognostic (1.51e-1)" "unprognostic (1.09e-2)" "unprognostic (4.89e-2)" "unprognostic (1.02e-2)" "unprognostic (1.70e-1)" "unprognostic (1.43e-1)" "unprognostic (5.29e-3)" "unprognostic (3.20e-1)" KIAA2026 FLJ20375 ENSG00000183354 KIAA2026 Q5HYC2 9 5881596-6008482 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 5 "Choroid plexus epithelial cells: 1520.3" "Cell type enriched" "Detected in all" 4 "choroid plexus epithelial cell: 1292.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002109 Uncertain Approved Nucleoplasm,Vesicles,Cytosol No No "Cluster 45: Eosinophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 47: Leukemia - Hemostasis" "Cluster 101: Choroid plexus epithelial cells - Ion transport" "Vesicles, Cytosol" Nucleoplasm "HPA002109: " "unprognostic (2.15e-1)" "unprognostic (1.25e-1)" "unprognostic (9.73e-2)" "unprognostic (2.21e-1)" "unprognostic (3.10e-2)" "unprognostic (1.94e-3)" "unprognostic (9.24e-3)" "unprognostic (2.64e-1)" "unprognostic (2.43e-1)" "unprognostic (2.59e-1)" "potential prognostic favorable (2.24e-5)" "unprognostic (4.14e-3)" "unprognostic (6.96e-3)" "unprognostic (7.45e-3)" "unprognostic (1.87e-2)" "unprognostic (2.05e-2)" "unprognostic (1.69e-1)" "unprognostic (3.36e-1)" "unprognostic (1.62e-1)" "unprognostic (4.74e-2)" "unprognostic (1.90e-1)" "unprognostic (2.09e-1)" "unprognostic (4.98e-2)" "unprognostic (9.77e-2)" "unprognostic (1.11e-1)" "unprognostic (4.11e-2)" "unprognostic (1.93e-2)" "unprognostic (1.93e-1)" "unprognostic (1.89e-1)" "unprognostic (2.06e-1)" "unprognostic (1.03e-1)" KICS2 "C12orf66, FLJ32549" ENSG00000174206 "KICSTOR subunit 2" Q96MD2 12 64186316-64222296 "Predicted intracellular proteins" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Macrophages, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046743, HPA052855" Uncertain Approved "Lysosomes,Cytokinetic bridge" Yes No "Cluster 43: Non-specific - Transcription & Translation" "Cluster 76: Non-specific - Metabolism" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 7 Lysosomes "Cytokinetic bridge" "HPA046743: , HPA052855: " "unprognostic (2.53e-2)" "unprognostic (3.11e-3)" "unprognostic (6.66e-3)" "unprognostic (9.75e-2)" "unprognostic (8.48e-2)" "unprognostic (2.44e-2)" "unprognostic (1.03e-1)" "unprognostic (6.21e-3)" "unprognostic (6.08e-3)" "unprognostic (4.90e-3)" "potential prognostic favorable (1.42e-4)" "unprognostic (2.11e-1)" "unprognostic (7.24e-2)" "unprognostic (4.19e-2)" "unprognostic (1.02e-1)" "unprognostic (2.44e-2)" "unprognostic (1.33e-3)" "unprognostic (6.47e-2)" "unprognostic (1.28e-1)" "unprognostic (1.99e-1)" "unprognostic (1.37e-1)" "unprognostic (3.12e-1)" "unprognostic (2.19e-1)" "unprognostic (2.95e-1)" "unprognostic (2.87e-2)" "unprognostic (4.58e-3)" "unprognostic (1.31e-1)" "unprognostic (3.22e-2)" "unprognostic (1.74e-1)" "unprognostic (1.74e-2)" "unprognostic (9.76e-2)" KIDINS220 ARMS ENSG00000134313 "Kinase D interacting substrate 220" Q9ULH0 2 8721081-8837630 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Neurogenesis "Disease variant, Hereditary spastic paraplegia, Intellectual disability, Neurodegeneration, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014790 Supported Uncertain Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 30: White matter - Myelination" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 16 Nucleoplasm "Vesicles, Cytosol" "HPA014790: " "unprognostic (3.15e-2)" "unprognostic (1.14e-1)" "unprognostic (6.62e-2)" "unprognostic (2.30e-3)" "unprognostic (8.10e-2)" "potential prognostic unfavorable (2.68e-4)" "unprognostic (1.82e-1)" "potential prognostic favorable (4.08e-5)" "unprognostic (1.97e-1)" "unprognostic (5.86e-2)" "validated prognostic favorable (9.82e-8)" "validated prognostic favorable (4.04e-4)" "unprognostic (3.31e-2)" "unprognostic (1.53e-2)" "unprognostic (1.39e-1)" "unprognostic (7.01e-2)" "unprognostic (2.26e-2)" "unprognostic (1.46e-2)" "unprognostic (8.13e-2)" "unprognostic (5.11e-2)" "unprognostic (4.68e-2)" "unprognostic (1.96e-1)" "unprognostic (1.84e-2)" "unprognostic (7.68e-2)" "unprognostic (7.04e-2)" "unprognostic (4.45e-2)" "unprognostic (5.69e-2)" "unprognostic (1.14e-1)" "unprognostic (2.26e-1)" "unprognostic (1.37e-1)" "unprognostic (3.36e-1)" KIF11 "Eg5, HKSP, KNSL1, TRIP5" ENSG00000138160 "Kinesin family member 11" P52732 10 92574105-92655395 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Motor protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 18.2;lymphoid tissue: 35.3" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 69.6;Erythrocyte progenitors: 145.3;Megakaryocyte progenitors: 90.1;Monocyte progenitors: 256.8;Neutrophil progenitors: 117.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA006916, HPA010093, HPA010568, CAB017617" Enhanced Supported "Vesicles,Mitotic spindle,Basal body,Cytosol,Mid piece,Principal piece,End piece" Yes Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 23: Choroid plexus - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 27: Non-specific - Cell proliferation" 16 "Cytosol, Mid piece" "Vesicles, Mitotic spindle, Basal body, Principal piece, End piece" "CAB017617: , HPA006916: , HPA010093: , HPA010568: " "unprognostic (1.65e-2)" "unprognostic (1.89e-1)" "unprognostic (2.46e-2)" "unprognostic (1.02e-1)" "unprognostic (3.10e-2)" "unprognostic (4.02e-1)" "unprognostic (3.88e-1)" "unprognostic (7.54e-2)" "unprognostic (5.38e-2)" "validated prognostic unfavorable (3.97e-4)" "validated prognostic unfavorable (4.41e-4)" "potential prognostic unfavorable (8.70e-10)" "validated prognostic unfavorable (7.61e-7)" "validated prognostic unfavorable (9.18e-5)" "potential prognostic unfavorable (7.79e-5)" "unprognostic (1.48e-2)" "unprognostic (7.72e-2)" "unprognostic (1.97e-1)" "unprognostic (3.93e-2)" "unprognostic (4.03e-2)" "potential prognostic unfavorable (8.86e-5)" "unprognostic (6.00e-3)" "unprognostic (7.17e-2)" "unprognostic (8.40e-2)" "unprognostic (4.03e-2)" "unprognostic (3.89e-2)" "unprognostic (1.91e-2)" "unprognostic (3.45e-1)" "unprognostic (1.94e-2)" "unprognostic (2.04e-1)" KIF12 ENSG00000136883 "Kinesin family member 12" 9 114086126-114099292 "Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "kidney: 214.1;pancreas: 91.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 115.3;Distal convoluted tubule cells: 94.5;Enteric stem cells: 47.0;Enterocytes: 54.2;Epididymal efferent duct absorptive cells: 62.9;Loop of henle epithelial cells: 93.6;Neuroendocrine cells: 86.6;Pancreatic duct cells: 66.8;Paneth cells: 54.1;Proximal tubule cells: 215.2;Renal collecting duct intercalated cells: 73.2;Renal collecting duct principal cells: 58.5;Renal connecting tubule cells: 97.5" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 12.2" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 96.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 23.3;liver cancer: 14.7" "Breast - Breast glandular cells, Colon - Colon enterocytes, Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA020192, HPA024127" Uncertain Approved "Nucleoplasm,Mid piece,Principal piece" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 33: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 88: Proximal tubular cells - Transmembrane transport" "Nucleoplasm, Mid piece, Principal piece" "HPA020192: , HPA024127: " "unprognostic (1.29e-3)" "unprognostic (2.51e-1)" "unprognostic (3.55e-2)" "unprognostic (5.48e-2)" "unprognostic (1.67e-1)" "unprognostic (2.13e-2)" "unprognostic (4.48e-2)" "unprognostic (1.63e-2)" "potential prognostic favorable (3.83e-5)" "unprognostic (1.15e-2)" "potential prognostic favorable (3.23e-6)" "unprognostic (5.30e-2)" "unprognostic (2.69e-1)" "unprognostic (4.09e-2)" "unprognostic (2.71e-2)" "unprognostic (2.70e-2)" "unprognostic (2.77e-1)" "unprognostic (2.42e-2)" "unprognostic (1.43e-2)" "unprognostic (9.48e-3)" "unprognostic (6.60e-2)" "unprognostic (1.50e-2)" "potential prognostic favorable (4.79e-4)" "unprognostic (2.87e-1)" "unprognostic (1.45e-1)" "unprognostic (1.22e-1)" "unprognostic (9.59e-2)" "unprognostic (2.91e-1)" KIF13A "bA500C11.2, RBKIN" ENSG00000137177 "Kinesin family member 13A" Q9H1H9 6 17759183-17987635 "Predicted intracellular proteins" "Cell cycle, Cell division, Protein transport, Transport" "Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 97.9" "Cell type enhanced" "Detected in all" "Myonuclei: 776.7;Neutrophils: 835.2;Oligodendrocyte progenitor cells: 1217.1" "Cell type enhanced" "Detected in all" "oligodendrocyte precursor cell: 1362.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 5.9" "Lineage enriched" "Detected in many" 4 "granulocytes: 5.9" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Endothelial cells, Skeletal muscle - Skeletal myocytes, Spleen - Fibroblasts_2, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029253, HPA029254" Uncertain Approved "Mid piece,Principal piece" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 4 "Mid piece, Principal piece" "HPA029253: , HPA029254: " "unprognostic (8.08e-2)" "unprognostic (1.66e-1)" "unprognostic (2.28e-1)" "unprognostic (2.98e-1)" "unprognostic (2.83e-2)" "unprognostic (6.69e-2)" "unprognostic (7.40e-2)" "potential prognostic favorable (7.01e-4)" "unprognostic (8.99e-2)" "unprognostic (1.44e-2)" "validated prognostic favorable (3.74e-7)" "validated prognostic favorable (7.43e-5)" "unprognostic (4.47e-2)" "potential prognostic unfavorable (2.47e-4)" "unprognostic (1.23e-1)" "unprognostic (2.29e-2)" "unprognostic (9.74e-2)" "unprognostic (2.84e-1)" "unprognostic (2.10e-2)" "unprognostic (3.89e-2)" "unprognostic (1.26e-1)" "unprognostic (1.52e-1)" "potential prognostic favorable (8.63e-4)" "unprognostic (1.68e-1)" "unprognostic (6.46e-3)" "unprognostic (5.40e-1)" "unprognostic (1.37e-2)" "unprognostic (1.05e-1)" "unprognostic (2.58e-1)" "unprognostic (4.56e-1)" "unprognostic (4.58e-2)" KIF13B "GAKIN, KIAA0639" ENSG00000197892 "Kinesin family member 13B" Q9NQT8 8 29067278-29263124 "Plasma proteins, Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "parathyroid gland: 152.0" "Cell type enhanced" "Detected in all" "Endometrial glandular cells: 1048.8;Endometrial luminal cells: 555.3;Mast cells: 697.4" "Cell type enhanced" "Detected in all" "oligodendrocyte: 687.8" "Cancer enriched" "Detected in all" 4 "Kidney Chromophobe (TCGA): 103.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025023, HPA049655" Enhanced NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 51: Secretory epithelial cells - Mixed function" 9 "HPA025023: , HPA049655: " "potential prognostic favorable (2.94e-4)" "unprognostic (1.54e-1)" "unprognostic (5.83e-3)" "unprognostic (1.24e-1)" "potential prognostic favorable (5.63e-4)" "unprognostic (8.76e-2)" "unprognostic (1.35e-1)" "unprognostic (8.61e-2)" "unprognostic (3.97e-3)" "unprognostic (3.91e-2)" "potential prognostic favorable (1.27e-10)" "unprognostic (1.27e-2)" "unprognostic (9.02e-3)" "unprognostic (1.08e-1)" "unprognostic (9.04e-2)" "unprognostic (4.49e-2)" "unprognostic (2.34e-1)" "unprognostic (5.02e-2)" "unprognostic (1.96e-2)" "unprognostic (2.31e-1)" "unprognostic (5.24e-3)" "potential prognostic unfavorable (9.04e-4)" "unprognostic (2.31e-1)" "unprognostic (9.65e-2)" "unprognostic (2.68e-2)" "unprognostic (1.80e-2)" "unprognostic (1.69e-2)" "unprognostic (2.74e-1)" "unprognostic (3.30e-1)" "unprognostic (8.94e-2)" "unprognostic (1.43e-1)" KIF14 KIAA0042 ENSG00000118193 "Kinesin family member 14" Q15058 1 200551497-200620751 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Motor protein" "Ciliopathy, Disease variant, Meckel syndrome, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.2;lymphoid tissue: 10.2" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 33.4;Early primary spermatocytes: 57.5;Enteric transient amplifying cells: 47.3;Erythrocyte progenitors: 74.3;Esophageal basal cells: 31.6;Gastric progenitor cells: 30.8;Megakaryocyte progenitors: 66.3;Monocyte progenitors: 181.7;Neutrophil progenitors: 93.1;Paneth cells: 38.7" "Cell type enhanced" "Detected in many" "lower rhombic lip: 5.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA038061, HPA058220" Uncertain Supported "Plasma membrane,Midbody ring,Cytosol,Calyx,Connecting piece,Mid piece,Principal piece,End piece" Yes Yes "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 45: Non-specific - Nuclear processes" "Cluster 27: Non-specific - Cell proliferation" 57 "Cytosol, End piece" "Plasma membrane, Midbody ring, Calyx, Connecting piece, Mid piece, Principal piece" "HPA038061: , HPA058220: " "unprognostic (6.10e-2)" "unprognostic (1.48e-1)" "unprognostic (1.32e-1)" "unprognostic (5.21e-2)" "unprognostic (4.97e-2)" "unprognostic (2.01e-1)" "unprognostic (1.77e-1)" "unprognostic (4.53e-3)" "unprognostic (1.09e-1)" "potential prognostic unfavorable (6.04e-4)" "validated prognostic unfavorable (2.84e-6)" "validated prognostic unfavorable (1.61e-4)" "unprognostic (1.44e-1)" "unprognostic (6.50e-2)" "unprognostic (3.85e-1)" "unprognostic (1.57e-1)" "potential prognostic unfavorable (2.01e-5)" "unprognostic (1.67e-3)" "unprognostic (3.64e-2)" "unprognostic (2.45e-2)" "unprognostic (3.18e-2)" "unprognostic (1.01e-2)" "unprognostic (8.28e-2)" "unprognostic (1.39e-2)" KIF15 "HKLP2, KNSL7, NY-BR-62" ENSG00000163808 "Kinesin family member 15" Q9NS87 3 44761721-44873376 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 4.9;lymphoid tissue: 8.6;testis: 6.8" "Group enriched" "Detected in some" 6 "Early spermatids: 142.3;Erythrocyte progenitors: 41.5;Late primary spermatocytes: 79.9;Late spermatids: 82.2;Megakaryocyte progenitors: 36.6;Monocyte progenitors: 36.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Mitotic cells (Thyroid)" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA035516, HPA035517, HPA061469" Approved NA NA "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Cell proliferation" 13 "HPA035516: , HPA035517: , HPA061469: " "potential prognostic unfavorable (2.99e-4)" "unprognostic (1.49e-1)" "unprognostic (2.92e-1)" "unprognostic (1.92e-1)" "unprognostic (2.59e-3)" "unprognostic (1.35e-1)" "unprognostic (1.19e-1)" "unprognostic (5.16e-2)" "potential prognostic favorable (6.03e-4)" "potential prognostic unfavorable (6.23e-5)" "potential prognostic unfavorable (3.13e-4)" "unprognostic (1.11e-1)" "unprognostic (2.77e-2)" "unprognostic (2.05e-1)" "unprognostic (1.43e-1)" "unprognostic (2.11e-2)" "unprognostic (3.79e-3)" "unprognostic (1.17e-1)" "unprognostic (8.52e-3)" "unprognostic (2.74e-1)" "unprognostic (1.58e-1)" KIF16B "C20orf23, dJ971B4.1, FLJ20135, SNX23" ENSG00000089177 "Kinesin family member 16B" Q96L93 20 16272104-16573448 "Predicted intracellular proteins" Transport "Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 425.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" HPA051198 Approved Uncertain Mitochondria NA NA "Cluster 18: Non-specific - Translation" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Breast cancer - Unknown function" "Cluster 18: Adrenal cortex cells - Steroidogensis" Mitochondria "HPA051198: " "unprognostic (3.02e-1)" "unprognostic (1.07e-1)" "unprognostic (3.73e-1)" "unprognostic (1.39e-2)" "unprognostic (5.54e-3)" "unprognostic (1.82e-1)" "unprognostic (5.47e-2)" "unprognostic (1.01e-2)" "unprognostic (2.03e-1)" "unprognostic (6.80e-2)" "validated prognostic favorable (4.53e-7)" "validated prognostic favorable (3.23e-4)" "unprognostic (1.20e-1)" "unprognostic (1.30e-2)" "unprognostic (3.00e-1)" "unprognostic (2.16e-2)" "unprognostic (9.08e-2)" "potential prognostic unfavorable (3.89e-4)" "unprognostic (1.17e-1)" "unprognostic (7.09e-2)" "unprognostic (6.94e-3)" "unprognostic (2.63e-2)" "unprognostic (6.91e-2)" "unprognostic (2.58e-1)" "unprognostic (1.75e-1)" "unprognostic (3.21e-1)" "unprognostic (1.25e-1)" "unprognostic (7.35e-2)" "unprognostic (1.65e-1)" "unprognostic (7.84e-2)" "unprognostic (3.13e-1)" KIF17 "KIAA1405, KIF17B, KIF3X, KLP-2, OSM-3" ENSG00000117245 "Kinesin family member 17" Q9P2E2 1 20664014-20718017 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 21.0" "Cell type enhanced" "Detected in many" "Early spermatids: 56.5;Endometrial ciliated cells: 18.6;Ependymal cells: 41.8;Epididymal efferent duct ciliated cells: 26.4;Fallopian tube ciliated cells: 21.6;Late primary spermatocytes: 35.2;Late spermatids: 164.0;Lymphatic endothelial cells: 17.8;Respiratory ciliated cells: 30.4;Vascular endothelial cells: 18.2" "Cell type enhanced" "Detected in many" "ependymal cell: 40.8" "Cancer enriched" "Detected in single" 5 "Testicular Germ Cell Tumor (TCGA): 3.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Minor Salivary Gland - Endothelial cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA032085 Enhanced Approved "Nucleoplasm,Plasma membrane,Primary cilium tip,Basal body,Cytosol,Acrosome,Principal piece" NA NA "Cluster 67: Testis - Mixed function" "Cluster 33: Neurons - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" Nucleoplasm "Plasma membrane, Primary cilium tip, Basal body, Cytosol, Acrosome, Principal piece" "HPA032085: " "unprognostic (2.19e-2)" "unprognostic (2.69e-2)" "potential prognostic favorable (3.20e-4)" "unprognostic (2.00e-1)" KIF18A "DKFZP434G2226, PPP1R99" ENSG00000121621 "Kinesin family member 18A" Q8NI77 11 28020619-28108156 "Essential proteins, Predicted intracellular proteins" "Protein transport, Transport" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 7.8;lymphoid tissue: 8.9;testis: 12.8" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 94.6;Erythrocyte progenitors: 72.4;Late primary spermatocytes: 92.8;Megakaryocyte progenitors: 79.7;Monocyte progenitors: 93.4;Neutrophil progenitors: 49.7" "Cell type enhanced" "Detected in some" "vascular associated smooth muscle cell: 7.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "basophil: 4.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA039312, HPA039484" Approved Supported "Microtubules,Cytokinetic bridge" Yes Yes "Cluster 5: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Non-specific - Cell proliferation" 20 "Microtubules, Cytokinetic bridge" "HPA039312: , HPA039484: " "unprognostic (2.07e-3)" "unprognostic (1.71e-1)" "unprognostic (5.85e-2)" "unprognostic (2.16e-1)" "unprognostic (2.40e-1)" "unprognostic (3.87e-3)" "unprognostic (2.87e-1)" "unprognostic (7.65e-2)" "unprognostic (2.93e-1)" "validated prognostic unfavorable (5.56e-8)" "validated prognostic unfavorable (3.15e-5)" "validated prognostic unfavorable (4.54e-6)" "validated prognostic unfavorable (8.13e-7)" "potential prognostic unfavorable (2.20e-5)" "unprognostic (2.00e-3)" "unprognostic (6.91e-2)" "unprognostic (3.12e-1)" "unprognostic (6.29e-2)" "unprognostic (2.50e-1)" "validated prognostic unfavorable (1.10e-4)" "validated prognostic unfavorable (4.29e-6)" "unprognostic (2.30e-2)" "unprognostic (5.83e-2)" "unprognostic (2.47e-2)" "unprognostic (1.61e-1)" "unprognostic (3.27e-1)" "unprognostic (1.83e-1)" "unprognostic (6.93e-3)" KIF18B ENSG00000186185 "Kinesin family member 18B" Q86Y91 17 44924709-44947773 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 11.9;lymphoid tissue: 13.4" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 22.8;Enteric transient amplifying cells: 22.6;Erythrocyte progenitors: 63.8;Esophageal basal cells: 16.3;Megakaryocyte progenitors: 40.1;Monocyte progenitors: 73.8;Neutrophil progenitors: 27.4;Oligodendrocyte progenitor cells: 12.9;Plasma cells: 12.1" "Cell type enriched" "Detected in some" 14 "oligodendrocyte precursor cell: 19.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Thyroid gland - Mitotic cells (Thyroid)" "Region enhanced" "Detected in single" "white matter: 1.4" "Low region specificity" "Detected in many" HPA024205 Enhanced Supported "Nucleoplasm,Nucleoli,Nuclear bodies,Microtubule ends,Cytosol" Yes Yes "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 27: Breast cancer - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 13 "Nucleoplasm, Microtubule ends" "Nucleoli, Nuclear bodies, Cytosol" "HPA024205: " "unprognostic (6.90e-2)" "unprognostic (2.21e-1)" "unprognostic (3.31e-1)" "unprognostic (6.31e-3)" "unprognostic (1.67e-1)" "unprognostic (3.07e-2)" "unprognostic (3.85e-1)" "unprognostic (8.27e-2)" "unprognostic (3.54e-2)" "validated prognostic unfavorable (1.10e-11)" "validated prognostic unfavorable (7.94e-8)" "potential prognostic unfavorable (1.39e-7)" "validated prognostic unfavorable (1.05e-6)" "validated prognostic unfavorable (8.91e-5)" "validated prognostic unfavorable (5.75e-6)" "validated prognostic unfavorable (2.95e-4)" "unprognostic (2.02e-1)" "unprognostic (1.88e-3)" "unprognostic (8.25e-2)" "unprognostic (7.67e-2)" "potential prognostic unfavorable (4.38e-4)" "unprognostic (1.28e-3)" "unprognostic (8.12e-2)" "unprognostic (4.40e-2)" "unprognostic (3.80e-3)" "unprognostic (1.06e-2)" "unprognostic (1.33e-1)" "unprognostic (2.55e-2)" KIF19 "FLJ37300, KIF19A" ENSG00000196169 "Kinesin family member 19" Q2TAC6 17 74326210-74355820 "Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 12.0;fallopian tube: 11.3;lymphoid tissue: 13.3" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 57.0;Ependymal cells: 46.4;Epididymal efferent duct ciliated cells: 45.7;Fallopian tube ciliated cells: 81.7;Neuroendocrine cells: 24.0;Oligodendrocyte progenitor cells: 17.6;Paneth cells: 34.8;Respiratory ciliated cells: 100.8;Schwann cells: 21.6" "Cell type enhanced" "Detected in some" "ependymal cell: 54.9;oligodendrocyte precursor cell: 23.9" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 3.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 2.1" "Lineage enriched" "Detected in single" 22 "T-cells: 2.1" "Group enriched" "Detected in some" 12 "Gastric cancer: 1.4;lung cancer: 4.9;prostate cancer: 4.4" "Liver - Vascular endothelial cells, Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043638, HPA073303" Enhanced Approved "Plasma membrane,Actin filaments,Centrosome" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 11: Neuronal - Sensory perception" "Cluster 107: Ciliated cells - Cilia assembly & function" "Plasma membrane" "Actin filaments, Centrosome" "HPA043638: , HPA073303: " "unprognostic (2.98e-1)" "unprognostic (3.65e-2)" "unprognostic (4.54e-2)" "unprognostic (1.98e-2)" "unprognostic (5.61e-2)" "unprognostic (1.98e-2)" "potential prognostic favorable (3.58e-4)" "potential prognostic unfavorable (4.20e-4)" "unprognostic (8.94e-2)" "unprognostic (1.51e-1)" "unprognostic (1.26e-2)" "unprognostic (1.67e-1)" KIF1A "ATSV, C2orf20, SPG30, UNC104" ENSG00000130294 "Kinesin family member 1A" Q12756 2 240713761-240824293 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Hydrolase, Isomerase, Motor protein" "Disease variant, Hereditary spastic paraplegia, Intellectual disability, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 121.5;pancreas: 32.2;retina: 54.3" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 104.0;Cone photoreceptor cells: 153.2;Corticotrophs: 212.1;Early primary spermatocytes: 132.7;Gonadotrophs: 100.2;Lactotrophs: 120.4;Müller glia: 106.1;Other brain neurons: 132.8;Pancreatic acinar cells: 114.5;Pancreatic islet cells: 129.2;Retinal amacrine cells: 220.6;Retinal bipolar cells: 284.2;Retinal ganglion cells: 181.6;Retinal horizontal cells: 334.6;Retinal pigment epithelial cells: 136.4;Rod photoreceptor cells: 115.8;Somatotrophs: 139.4;Thyrotrophs: 107.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 22.9;Ovary Serous Cystadenocarcinoma (TCGA): 23.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "lung cancer: 49.1;Neuroblastoma: 78.9" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Prostate - Prostate glandular cells, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005442 Uncertain "Centriolar satellite,Cytosol" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 18 "Centriolar satellite" Cytosol "HPA005442: " "unprognostic (3.55e-2)" "unprognostic (7.42e-2)" "unprognostic (1.92e-1)" "unprognostic (2.12e-1)" "unprognostic (1.73e-1)" "unprognostic (1.85e-1)" "unprognostic (4.82e-2)" "unprognostic (2.34e-1)" "unprognostic (7.56e-3)" "unprognostic (6.97e-2)" "unprognostic (1.25e-1)" "unprognostic (1.26e-3)" "unprognostic (1.99e-1)" "unprognostic (1.43e-2)" "unprognostic (5.05e-3)" "unprognostic (2.71e-1)" "unprognostic (2.78e-1)" "unprognostic (2.29e-2)" "unprognostic (1.48e-2)" "unprognostic (2.77e-1)" "unprognostic (3.00e-1)" KIF1B "CMT2, CMT2A, HMSNII, KIAA0591, KLP" ENSG00000054523 "Kinesin family member 1B" O60333 1 10210570-10381603 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Isomerase, Motor protein" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 118.5;skeletal muscle: 184.8;tongue: 141.5" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 1153.1;Myonuclei: 1337.6;Neutrophil progenitors: 896.0;Neutrophils: 1943.5;Rod photoreceptor cells: 1477.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 8.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 8.0" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015177, HPA026447" Approved Uncertain "Microtubules,Mid piece,Principal piece,End piece" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 28 "Microtubules, Mid piece, Principal piece, End piece" "CAB015177: , HPA026447: " "unprognostic (1.78e-1)" "unprognostic (2.14e-1)" "unprognostic (4.78e-2)" "unprognostic (3.75e-2)" "unprognostic (2.42e-2)" "unprognostic (8.60e-2)" "unprognostic (1.63e-2)" "unprognostic (3.80e-2)" "unprognostic (1.71e-1)" "unprognostic (1.65e-3)" "validated prognostic favorable (1.18e-7)" "validated prognostic favorable (6.48e-4)" "unprognostic (2.68e-2)" "unprognostic (2.34e-2)" "unprognostic (1.54e-2)" "unprognostic (1.18e-1)" "unprognostic (1.01e-1)" "unprognostic (5.13e-3)" "unprognostic (3.26e-2)" "unprognostic (3.34e-2)" "unprognostic (9.21e-2)" "unprognostic (1.30e-1)" "unprognostic (1.38e-1)" "unprognostic (4.02e-1)" "unprognostic (1.41e-1)" "unprognostic (3.62e-2)" "unprognostic (1.63e-1)" "unprognostic (8.07e-2)" "unprognostic (3.39e-2)" "unprognostic (3.03e-2)" "unprognostic (1.15e-1)" KIF1C "SAX2, SPAX2, SPG58" ENSG00000129250 "Kinesin family member 1C" O43896 17 4997950-5028401 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Motor protein" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 525.9;tongue: 363.3" "Cell type enhanced" "Detected in many" "Colonocytes: 140.2;Esophageal apical cells: 327.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Pituitary gland - Endothelial cells, Prostate - Smooth muscle cells, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024602, HPA045020" Approved Approved "Nucleoplasm,Nucleoli,Principal piece" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 30 "Nucleoplasm, Nucleoli, Principal piece" "HPA024602: , HPA045020: " "unprognostic (8.69e-2)" "unprognostic (5.32e-2)" "unprognostic (1.56e-3)" "unprognostic (3.20e-3)" "unprognostic (3.82e-2)" "unprognostic (4.15e-2)" "unprognostic (4.95e-1)" "unprognostic (1.18e-1)" "unprognostic (1.43e-1)" "unprognostic (1.07e-3)" "validated prognostic favorable (4.54e-9)" "validated prognostic favorable (2.59e-4)" "potential prognostic favorable (4.62e-6)" "unprognostic (1.36e-1)" "unprognostic (1.93e-1)" "unprognostic (1.36e-1)" "unprognostic (2.82e-1)" "unprognostic (7.23e-3)" "unprognostic (2.11e-1)" "unprognostic (1.05e-1)" "unprognostic (1.13e-1)" "unprognostic (2.23e-2)" "unprognostic (2.61e-1)" "unprognostic (1.61e-1)" "unprognostic (3.52e-1)" "unprognostic (7.21e-2)" "unprognostic (1.03e-1)" "unprognostic (2.68e-1)" "unprognostic (7.81e-2)" "unprognostic (8.45e-2)" "unprognostic (6.66e-2)" KIF20A "MKLP2, RAB6KIFL" ENSG00000112984 "Kinesin family member 20A" O95235 5 138178719-138187723 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Motor protein" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 13.3;lymphoid tissue: 22.9;testis: 10.9" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 13.3;Differentiating spermatogonia: 11.9;Early primary spermatocytes: 17.1;Enteric transient amplifying cells: 9.5;Erythrocyte progenitors: 22.5;Esophageal basal cells: 11.5;Extravillous trophoblasts: 14.0;Gastric progenitor cells: 16.7;Hofbauer cells: 9.2;Late primary spermatocytes: 13.6;Megakaryocyte progenitors: 14.4;Migrating cytotrophoblasts: 15.1;Monocyte progenitors: 39.1;Neutrophil progenitors: 13.5;Oocytes: 13.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 12 "NK-cell: 6.7;T-reg: 2.5" "Group enriched" "Detected in many" 46 "NK-cells: 6.7;T-cells: 2.5" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA036909, HPA036910" Approved Approved "Nucleoplasm,Cytokinetic bridge,Cleavage furrow,Mitotic spindle" Yes Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 12: Non-specific - Vasculature" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Non-specific - Cell proliferation" 26 "Nucleoplasm, Cytokinetic bridge, Cleavage furrow, Mitotic spindle" "HPA036909: , HPA036910: " "unprognostic (6.91e-3)" "unprognostic (7.53e-2)" "unprognostic (1.21e-1)" "unprognostic (7.31e-2)" "unprognostic (1.54e-2)" "unprognostic (1.50e-1)" "unprognostic (1.16e-1)" "unprognostic (4.61e-2)" "unprognostic (5.83e-2)" "potential prognostic unfavorable (1.17e-5)" "validated prognostic unfavorable (8.01e-11)" "validated prognostic unfavorable (1.58e-6)" "potential prognostic unfavorable (5.78e-12)" "validated prognostic unfavorable (2.10e-9)" "validated prognostic unfavorable (1.50e-7)" "validated prognostic unfavorable (1.58e-5)" "validated prognostic unfavorable (4.64e-5)" "unprognostic (1.37e-1)" "unprognostic (2.03e-1)" "unprognostic (2.17e-1)" "unprognostic (2.72e-1)" "potential prognostic unfavorable (2.06e-5)" "unprognostic (1.78e-3)" "unprognostic (1.03e-1)" "unprognostic (6.51e-2)" "unprognostic (1.64e-1)" "unprognostic (9.01e-2)" "unprognostic (1.85e-1)" "unprognostic (1.46e-1)" "unprognostic (9.84e-2)" "unprognostic (4.39e-2)" KIF20B "CT90, KRMP1, MPHOSPH1, MPP1" ENSG00000138182 "Kinesin family member 20B" Q96Q89 10 89701590-89774939 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Motor protein" Oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 9.6;lymphoid tissue: 9.1" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 136.5;Early primary spermatocytes: 186.7;Erythrocyte progenitors: 233.4;Megakaryocyte progenitors: 135.3;Monocyte progenitors: 233.5" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 73.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA050214 Supported Supported "Nucleoplasm,Cytokinetic bridge,Midbody,Centrosome,Basal body,Cytosol,Perinuclear theca" Yes Yes "Cluster 5: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 15: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 27: Non-specific - Cell proliferation" 8 "Nucleoplasm, Cytokinetic bridge, Basal body" "Midbody, Centrosome, Cytosol, Perinuclear theca" "HPA050214: " "unprognostic (1.03e-2)" "unprognostic (2.21e-1)" "unprognostic (1.44e-1)" "unprognostic (6.48e-2)" "unprognostic (2.42e-2)" "unprognostic (2.14e-1)" "unprognostic (8.55e-3)" "unprognostic (1.11e-1)" "potential prognostic favorable (1.26e-4)" "unprognostic (2.19e-1)" "potential prognostic unfavorable (8.47e-4)" "potential prognostic unfavorable (6.31e-4)" "unprognostic (6.50e-3)" "unprognostic (1.69e-1)" "unprognostic (1.39e-1)" "unprognostic (1.03e-2)" "unprognostic (4.18e-3)" "validated prognostic unfavorable (1.82e-5)" "validated prognostic unfavorable (3.64e-7)" "unprognostic (2.75e-3)" "unprognostic (1.48e-2)" "unprognostic (2.04e-1)" "unprognostic (2.04e-2)" "unprognostic (1.12e-1)" "unprognostic (8.42e-2)" KIF21A "FEOM1, FLJ20052" ENSG00000139116 "Kinesin family member 21A" Q7Z4S6 12 39293228-39443390 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Motor protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 71.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 496.6;Esophageal apical cells: 491.8;Fallopian tube ciliated cells: 438.9;Respiratory ciliated cells: 585.7;Retinal bipolar cells: 444.7" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 99.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 7.1;MAIT T-cell: 3.4;memory CD4 T-cell: 4.4;memory CD8 T-cell: 7.3;naive CD8 T-cell: 4.8;NK-cell: 3.0;T-reg: 2.2" "Group enriched" "Detected in many" 9 "NK-cells: 3.0;T-cells: 7.3" "Cancer enhanced" "Detected in all" "Neuroblastoma: 113.1" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells, Lung - Respiratory ciliated cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022079, HPA058432" Enhanced Approved Cytosol NA NA "Cluster 1: T-cells - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 45: Non-specific - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 6 Cytosol "CAB022079: , HPA058432: " "unprognostic (2.87e-1)" "unprognostic (4.36e-3)" "unprognostic (2.60e-1)" "unprognostic (5.02e-1)" "unprognostic (1.20e-1)" "unprognostic (1.22e-1)" "unprognostic (1.05e-1)" "unprognostic (1.39e-2)" "unprognostic (1.12e-1)" "unprognostic (1.12e-2)" "potential prognostic favorable (2.06e-5)" "unprognostic (6.28e-2)" "unprognostic (6.72e-2)" "potential prognostic unfavorable (4.55e-4)" "unprognostic (1.93e-3)" "unprognostic (1.40e-1)" "unprognostic (1.03e-1)" "unprognostic (2.53e-2)" "unprognostic (3.64e-2)" "unprognostic (1.28e-1)" "unprognostic (3.55e-1)" "unprognostic (1.98e-1)" "unprognostic (4.92e-3)" "unprognostic (3.41e-2)" "unprognostic (1.45e-1)" "unprognostic (4.30e-2)" "unprognostic (7.36e-2)" "unprognostic (3.31e-1)" "unprognostic (7.71e-2)" "unprognostic (5.82e-2)" "unprognostic (2.45e-1)" KIF21B "DKFZP434J212, KIAA0449" ENSG00000116852 "Kinesin family member 21B" O75037 1 200969390-201023714 "Plasma proteins, Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 32.3;brain: 19.3;retina: 19.9" "Cell type enhanced" "Detected in many" "Astrocytes: 36.2;Cone photoreceptor cells: 58.0;Early spermatids: 47.0;Late spermatids: 157.0;Microglia: 33.7;Müller glia: 101.1;Neutrophil progenitors: 76.8;Neutrophils: 86.1;NK-cells: 39.6;Retinal bipolar cells: 41.1;Retinal pigment epithelial cells: 38.4;Rod photoreceptor cells: 42.1;T-cells: 33.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "basophil: 6.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 6.0" "Group enriched" "Detected in many" 8 "Leukemia: 30.9;lymphoma: 31.2;Myeloma: 75.3" "Colon - T-cells, Kidney - T-cells, Prostate - T-cells, Spleen - B-cells (Spleen), Testis - Late spermatids, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027249, HPA027274" Approved Uncertain "Plasma membrane,Mitotic spindle,Cytosol,Mid piece" Yes No "Cluster 42: Non-specific - Vesicular transport" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 5 "Plasma membrane, Mid piece" "Mitotic spindle, Cytosol" "HPA027249: , HPA027274: " "unprognostic (1.45e-1)" "unprognostic (1.65e-1)" "unprognostic (2.24e-3)" "unprognostic (6.62e-2)" "unprognostic (5.65e-2)" "unprognostic (8.30e-2)" "unprognostic (1.92e-1)" "potential prognostic favorable (4.78e-4)" "unprognostic (3.35e-3)" "unprognostic (8.61e-2)" "unprognostic (7.40e-2)" "unprognostic (1.09e-2)" "unprognostic (1.41e-2)" "unprognostic (2.05e-2)" "unprognostic (4.43e-2)" "potential prognostic unfavorable (4.48e-4)" "unprognostic (1.87e-1)" "unprognostic (5.05e-2)" "unprognostic (1.32e-1)" "unprognostic (2.17e-1)" "unprognostic (1.69e-1)" "unprognostic (3.07e-1)" "unprognostic (1.20e-2)" "unprognostic (1.84e-1)" KIF22 "Kid, KNSL4, OBP-1, OBP-2" ENSG00000079616 "Kinesin family member 22" Q14807 16 29790727-29805385 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA-binding, Motor protein" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 53.6" "Cell type enriched" "Detected in many" 5 "Hepatocytes: 682.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048213, HPA075670" Enhanced Supported "Nuclear speckles" NA Yes "Cluster 5: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 33: Neurons - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 93: Hepatocytes - Bile production & excretion" 26 "Nuclear speckles" "HPA048213: , HPA075670: " "unprognostic (4.08e-2)" "unprognostic (3.96e-2)" "unprognostic (4.65e-2)" "potential prognostic favorable (8.51e-4)" "unprognostic (4.02e-1)" "potential prognostic favorable (6.30e-4)" "unprognostic (1.08e-1)" "potential prognostic favorable (5.67e-4)" "unprognostic (2.30e-2)" "unprognostic (1.48e-1)" "unprognostic (1.03e-1)" "unprognostic (6.72e-2)" "unprognostic (7.01e-3)" "potential prognostic unfavorable (4.05e-5)" "unprognostic (4.06e-3)" "unprognostic (5.64e-3)" "unprognostic (1.57e-3)" "unprognostic (2.78e-2)" "unprognostic (4.52e-2)" "unprognostic (1.32e-1)" "unprognostic (2.19e-2)" "potential prognostic unfavorable (2.98e-4)" "unprognostic (5.17e-3)" "unprognostic (2.57e-2)" "unprognostic (6.76e-2)" "unprognostic (1.73e-1)" "unprognostic (1.07e-1)" "unprognostic (7.54e-2)" "unprognostic (4.35e-1)" "unprognostic (7.80e-3)" "unprognostic (3.87e-2)" KIF23 "KNSL5, MKLP-1, MKLP1" ENSG00000137807 "Kinesin family member 23" Q02241 15 69414246-69448427 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Motor protein" "Congenital dyserythropoietic anemia, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.4;lymphoid tissue: 14.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 41.7;Differentiating spermatogonia: 34.8;Early primary spermatocytes: 45.5;Enteric transient amplifying cells: 33.7;Erythrocyte progenitors: 86.7;Extravillous trophoblasts: 49.4;Late primary spermatocytes: 60.8;Megakaryocyte progenitors: 36.1;Migrating cytotrophoblasts: 52.5;Monocyte progenitors: 74.3;Neutrophil progenitors: 36.2" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 14.2" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 4 "choroid plexus: 2.9" "Immune cell enhanced" "Detected in some" "eosinophil: 4.6" "Group enriched" "Detected in many" 13 "granulocytes: 4.6;monocytes: 1.2;T-cells: 1.2" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Prostate - Smooth muscle cells, Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB010414, HPA045208, HPA068831" Uncertain Supported "Nucleoplasm,Midbody ring,Mitotic spindle,Mid piece,Principal piece,Annulus" Yes Yes "Cluster 25: Non-specific - Unknown function" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 36: Choroid plexus - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 27: Non-specific - Cell proliferation" 78 Nucleoplasm "Midbody ring, Mitotic spindle, Mid piece, Principal piece, Annulus" "CAB010414: , HPA045208: , HPA068831: " "unprognostic (3.17e-2)" "unprognostic (1.43e-1)" "unprognostic (9.49e-2)" "unprognostic (1.32e-1)" "unprognostic (9.50e-2)" "unprognostic (1.48e-1)" "unprognostic (1.88e-1)" "unprognostic (2.79e-2)" "unprognostic (5.14e-2)" "potential prognostic unfavorable (1.64e-4)" "validated prognostic unfavorable (3.72e-10)" "validated prognostic unfavorable (2.37e-6)" "potential prognostic unfavorable (1.50e-7)" "validated prognostic unfavorable (9.80e-6)" "validated prognostic unfavorable (6.19e-7)" "validated prognostic unfavorable (4.08e-6)" "validated prognostic unfavorable (1.82e-4)" "unprognostic (9.01e-2)" "unprognostic (2.52e-1)" "unprognostic (1.84e-1)" "unprognostic (1.80e-2)" "validated prognostic unfavorable (2.85e-5)" "validated prognostic unfavorable (9.51e-5)" "unprognostic (3.17e-2)" "unprognostic (1.69e-2)" "unprognostic (1.72e-2)" "unprognostic (1.93e-2)" "unprognostic (3.27e-2)" "unprognostic (1.53e-1)" "unprognostic (5.97e-2)" KIF24 "bA571F15.4, C9orf48, FLJ10933, FLJ43884" ENSG00000186638 "Kinesin family member 24" Q5T7B8 9 34252380-34329268 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 10.5" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 38.4;Differentiating spermatogonia: 41.2;Early primary spermatocytes: 46.0;Endometrial ciliated cells: 38.3;Ependymal cells: 76.2;Epicardial cells: 50.0;Erythrocyte progenitors: 35.6;Fallopian tube ciliated cells: 43.6;Late spermatids: 68.1;Respiratory ciliated cells: 60.4;Respiratory deuterosomal cells: 97.4" "Cell type enhanced" "Detected in many" "ependymal cell: 93.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 10 "basophil: 3.0" "Lineage enriched" "Detected in single" 17 "granulocytes: 3.0" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Prostate - Smooth muscle cells, Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA020643 Uncertain NA NA "Cluster 39: Testis - Nuclear processes" "Cluster 17: Choroid plexus - Cilium" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Cell proliferation" 6 "HPA020643: " "unprognostic (3.59e-1)" "unprognostic (3.43e-1)" "unprognostic (1.18e-1)" "unprognostic (1.54e-2)" "unprognostic (2.60e-1)" "unprognostic (8.98e-2)" "unprognostic (2.32e-1)" "unprognostic (2.16e-1)" "potential prognostic favorable (7.34e-4)" "unprognostic (1.43e-1)" "unprognostic (4.61e-2)" "unprognostic (5.89e-2)" "unprognostic (6.24e-3)" "unprognostic (1.75e-3)" "unprognostic (1.41e-1)" "unprognostic (1.37e-2)" "unprognostic (8.68e-2)" "unprognostic (2.15e-2)" "unprognostic (2.22e-1)" "unprognostic (2.27e-2)" "unprognostic (1.06e-1)" "unprognostic (8.64e-3)" "potential prognostic favorable (7.75e-4)" "unprognostic (1.70e-1)" "unprognostic (9.61e-2)" KIF25 KNSL3 ENSG00000125337 "Kinesin family member 25" Q9UIL4 6 167996241-168045091 "Predicted intracellular proteins" "Motor protein" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 6 "brain: 6.4;retina: 2.3" "Cell type enhanced" "Detected in some" "Bergmann glia: 17.5;Brain inhibitory neurons: 8.3;Epididymal clear cells: 8.2;Retinal bipolar cells: 7.9;Retinal pigment epithelial cells: 38.4;Vascular endothelial cells: 13.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA046153 Uncertain NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "HPA046153: " "unprognostic (1.59e-1)" "unprognostic (1.17e-1)" "unprognostic (2.43e-1)" KIF26A "DKFZP434N178, KIAA1236" ENSG00000066735 "Kinesin family member 26A" Q9ULI4 14 104136454-104180894 "Predicted intracellular proteins" "Motor protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 53.2;Differentiating spermatogonia: 13.7;Erythrocyte progenitors: 30.2;Gastric chief cells: 9.8;Lymphatic endothelial cells: 13.8;Retinal horizontal cells: 14.0;Vascular endothelial cells: 13.0" "Cell type enhanced" "Detected in many" "endothelial cell: 13.1;pericyte: 9.7" "Group enriched" "Detected in many" 5 "Stomach Adenocarcinoma (TCGA): 5.7;Testicular Germ Cell Tumor (TCGA): 22.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "cervical cancer: 16.9;Neuroblastoma: 58.5" "Adipose subcutaneous - Endothelial cells, Adrenal gland - Adrenal medulla cells, Heart muscle - Endothelial cells, Minor Salivary Gland - Endothelial cells, Prostate - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA046882, HPA060346" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol,Connecting piece,Flagellar centriole" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 23: Choroid plexus - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 4 "Plasma membrane, Flagellar centriole" "Nucleoplasm, Cytosol, Connecting piece" "HPA046882: , HPA060346: " "unprognostic (4.74e-2)" "unprognostic (4.39e-1)" "unprognostic (2.52e-1)" "unprognostic (6.40e-2)" "unprognostic (4.37e-2)" "unprognostic (2.54e-2)" "unprognostic (4.42e-1)" "unprognostic (1.98e-3)" "unprognostic (5.86e-2)" "unprognostic (4.73e-3)" "validated prognostic favorable (2.49e-5)" "validated prognostic favorable (3.82e-4)" "unprognostic (4.22e-2)" "unprognostic (6.28e-2)" "unprognostic (5.81e-3)" "unprognostic (5.40e-2)" "unprognostic (1.36e-2)" "unprognostic (2.08e-2)" "unprognostic (1.04e-1)" "unprognostic (2.02e-1)" "unprognostic (2.34e-1)" KIF26B FLJ10157 ENSG00000162849 "Kinesin family member 26B" Q2KJY2 1 245154985-245709432 "Predicted intracellular proteins" "Developmental protein, Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.4" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 167.8;Brain inhibitory neurons: 183.5;Endometrial stromal cells: 217.7;Loop of henle epithelial cells: 156.0;Microglia: 244.9;Oligodendrocyte progenitor cells: 565.4;Other brain neurons: 141.3;Papillary tip epithelial cells: 212.1;Proximal tubule cells: 215.0;Renal collecting duct principal cells: 477.6;Renal connecting tubule cells: 237.1" "Cell type enhanced" "Detected in all" "MGE interneuron: 774.3;oligodendrocyte precursor cell: 654.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 18 "plasmacytoid DC: 1.8" "Lineage enriched" "Detected in single" 18 "dendritic cells: 1.8" "Cancer enriched" "Detected in many" 5 "Neuroblastoma: 18.4" "Adipose visceral - Adipose progenitor cells, Prostate - Fibroblasts, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027709, HPA028478, HPA028561, HPA028562" Enhanced Approved "Plasma membrane,Microtubules,Cytokinetic bridge,Primary cilium" Yes NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 27: Cerebellum - Synaptic function" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 102: Non-specific - Mixed function" 2 "Microtubules, Primary cilium" "Plasma membrane, Cytokinetic bridge" "HPA027709: , HPA028478: , HPA028561: , HPA028562: " "potential prognostic favorable (1.11e-4)" "unprognostic (1.96e-1)" "unprognostic (6.83e-3)" "unprognostic (5.97e-3)" "unprognostic (1.57e-2)" "unprognostic (9.28e-2)" "unprognostic (4.17e-2)" "unprognostic (1.06e-2)" "unprognostic (5.53e-2)" "unprognostic (1.40e-1)" "unprognostic (4.06e-1)" "unprognostic (4.03e-2)" "unprognostic (1.11e-1)" "unprognostic (1.96e-1)" "validated prognostic unfavorable (6.64e-4)" "validated prognostic unfavorable (4.16e-7)" "unprognostic (7.25e-3)" "unprognostic (7.63e-2)" "unprognostic (1.41e-1)" "unprognostic (4.01e-2)" "unprognostic (1.58e-1)" "unprognostic (8.70e-2)" "unprognostic (4.31e-2)" "unprognostic (1.42e-1)" KIF27 DKFZp434D0917 ENSG00000165115 "Kinesin family member 27" Q86VH2 9 83834099-83921465 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 24.5" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 265.0;Endometrial ciliated cells: 256.0;Ependymal cells: 312.1;Epididymal efferent duct ciliated cells: 266.1;Fallopian tube ciliated cells: 280.2;Neutrophils: 194.9;Respiratory ciliated cells: 296.1" "Group enriched" "Detected in all" 4 "choroid plexus epithelial cell: 281.1;ependymal cell: 337.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 16.2" "Lineage enriched" "Detected in many" 9 "granulocytes: 16.2" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 24: Neutrophils - Innate immunity signal integration" 2 "unprognostic (6.92e-2)" "unprognostic (1.18e-1)" "unprognostic (3.54e-1)" "unprognostic (3.32e-3)" "unprognostic (3.31e-3)" "unprognostic (2.26e-1)" "unprognostic (1.49e-1)" "unprognostic (7.91e-2)" "unprognostic (3.47e-3)" "unprognostic (5.44e-2)" "unprognostic (1.09e-2)" "potential prognostic favorable (3.63e-5)" "unprognostic (5.90e-2)" "unprognostic (9.80e-3)" "unprognostic (1.20e-1)" "unprognostic (2.02e-1)" "unprognostic (2.04e-1)" "unprognostic (1.02e-2)" "unprognostic (1.37e-1)" "unprognostic (2.08e-1)" "unprognostic (2.31e-2)" "unprognostic (1.00e-2)" "unprognostic (3.46e-1)" "unprognostic (4.11e-3)" "unprognostic (1.64e-1)" "unprognostic (1.43e-1)" "unprognostic (1.37e-1)" "unprognostic (1.55e-1)" "unprognostic (4.38e-2)" "unprognostic (2.09e-2)" KIF2A "HK2, KIF2" ENSG00000068796 "Kinesin family member 2A" O00139 5 62306162-62391025 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Mitosis, Neurogenesis" "Developmental protein, Motor protein" "Cancer-related genes, Disease variant, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Megakaryocytes: 457.4;Platelets: 1557.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004715, HPA004716" Approved Supported "Nucleoplasm,Nucleoli,Mitotic spindle,Centrosome,Basal body,Cytosol,Mid piece,Principal piece,Annulus" Yes No 350000 "Cluster 1: T-cells - Unknown function" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 47: Platelets - Hemostasis" 42 "Nucleoplasm, Nucleoli, Centrosome, Basal body, Annulus" "Mitotic spindle, Cytosol, Mid piece, Principal piece" "HPA004715: , HPA004716: " "unprognostic (1.85e-1)" "unprognostic (8.24e-2)" "unprognostic (4.52e-1)" "unprognostic (1.71e-1)" "unprognostic (8.71e-3)" "unprognostic (2.11e-2)" "unprognostic (2.11e-1)" "unprognostic (1.89e-2)" "unprognostic (2.79e-3)" "potential prognostic unfavorable (9.89e-6)" "unprognostic (1.25e-3)" "unprognostic (6.55e-3)" "unprognostic (6.76e-2)" "potential prognostic unfavorable (1.96e-4)" "unprognostic (2.68e-3)" "unprognostic (9.74e-2)" "unprognostic (1.62e-3)" "unprognostic (2.14e-2)" "unprognostic (4.43e-1)" "unprognostic (2.40e-2)" "potential prognostic unfavorable (4.38e-5)" "unprognostic (8.45e-2)" "potential prognostic unfavorable (1.16e-4)" "unprognostic (1.14e-1)" "unprognostic (2.73e-2)" "unprognostic (1.48e-1)" "unprognostic (1.01e-1)" "unprognostic (1.23e-1)" "unprognostic (1.94e-1)" "unprognostic (6.24e-2)" "unprognostic (1.32e-1)" KIF2B ENSG00000141200 "Kinesin family member 2B" Q8N4N8 17 53822927-53825193 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 705 "testis: 70.5" "Group enriched" "Detected in some" 127 "Early spermatids: 817.0;Late primary spermatocytes: 239.8;Late spermatids: 765.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA023081, HPA023103, HPA024795" Uncertain Uncertain "Nucleoli,Microtubules,Cytokinetic bridge,Mitotic spindle,Mid piece,Principal piece,End piece" Yes NA "Cluster 6: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 5 "Microtubules, Cytokinetic bridge, Mitotic spindle" "Nucleoli, Mid piece, Principal piece, End piece" "HPA023081: , HPA023103: , HPA024795: " KIF2C "CT139, KNSL6, MCAK" ENSG00000142945 "Kinesin family member 2C" Q99661 1 44739818-44767767 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 31.1;lymphoid tissue: 34.8;testis: 72.6" "Cell type enriched" "Detected in many" 5 "Late spermatids: 3084.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 2.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Late spermatids" "Region enhanced" "Detected in some" "white matter: 2.1" "Not detected" "Not detected" "HPA006219, HPA079172, CAB080091" Enhanced Approved Nucleoplasm,Midbody,Centrosome,Cytosol Yes Yes "Cluster 9: T-regs - Cell cycle regulation" "Cluster 39: Testis - Nuclear processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 37: Non-specific - mRNA processing" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 21 "Nucleoplasm, Midbody, Centrosome" Cytosol "CAB080091: , HPA006219: , HPA079172: " "unprognostic (3.89e-2)" "unprognostic (7.14e-2)" "unprognostic (1.64e-2)" "unprognostic (2.04e-1)" "unprognostic (2.45e-2)" "unprognostic (2.41e-2)" "unprognostic (3.60e-1)" "unprognostic (5.59e-2)" "unprognostic (2.08e-1)" "unprognostic (1.26e-3)" "potential prognostic unfavorable (1.25e-7)" "unprognostic (1.33e-3)" "potential prognostic unfavorable (1.49e-8)" "validated prognostic unfavorable (6.27e-8)" "validated prognostic unfavorable (5.57e-8)" "validated prognostic unfavorable (2.61e-4)" "validated prognostic unfavorable (2.26e-5)" "unprognostic (1.01e-1)" "unprognostic (2.05e-1)" "unprognostic (1.75e-1)" "unprognostic (9.29e-3)" "potential prognostic unfavorable (6.70e-4)" "unprognostic (5.27e-2)" "unprognostic (5.80e-2)" "unprognostic (3.13e-2)" "unprognostic (1.29e-2)" "unprognostic (4.21e-3)" "unprognostic (6.68e-2)" "unprognostic (1.34e-1)" "unprognostic (1.41e-2)" "unprognostic (2.25e-1)" KIF3A "FLA10, KLP-20" ENSG00000131437 "Kinesin family member 3A" Q9Y496 5 132692628-132737638 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 40.4;retina: 31.3" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 194.0;Brain inhibitory neurons: 190.0;Gonadotrophs: 202.7;Other brain neurons: 195.2;Respiratory ciliated cells: 204.6;Retinal horizontal cells: 220.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 10 "basophil: 68.3" "Lineage enriched" "Detected in all" 10 "granulocytes: 68.3" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037085, HPA063063" Approved Approved "Nucleoplasm,Primary cilium,Basal body,Cytosol" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 31 "Nucleoplasm, Primary cilium, Basal body, Cytosol" "CAB037085: , HPA063063: " "unprognostic (2.37e-2)" "unprognostic (1.11e-3)" "unprognostic (1.85e-1)" "unprognostic (4.60e-3)" "unprognostic (1.51e-2)" "unprognostic (1.82e-1)" "unprognostic (8.74e-2)" "unprognostic (5.28e-3)" "unprognostic (3.10e-1)" "unprognostic (7.63e-2)" "potential prognostic favorable (1.76e-5)" "unprognostic (1.54e-2)" "unprognostic (1.46e-1)" "unprognostic (1.83e-3)" "unprognostic (6.41e-3)" "unprognostic (8.61e-2)" "unprognostic (1.35e-1)" "unprognostic (9.53e-3)" "unprognostic (9.00e-2)" "unprognostic (8.15e-2)" "potential prognostic unfavorable (7.47e-4)" "unprognostic (4.26e-2)" "potential prognostic unfavorable (1.66e-4)" "unprognostic (9.89e-2)" "unprognostic (1.56e-1)" "unprognostic (1.19e-1)" "unprognostic (5.43e-2)" "unprognostic (2.08e-2)" "unprognostic (1.57e-1)" "unprognostic (9.86e-2)" "unprognostic (4.01e-2)" KIF3B "FLA8, KIAA0359, KLP-11" ENSG00000101350 "Kinesin family member 3B" O15066 20 32277651-32335011 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Motor protein" "Ciliopathy, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 156.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007119 Approved Approved "Nucleoplasm,Primary cilium tip,Cytosol,Connecting piece,Flagellar centriole" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 62: Non-specific - Plasma proteins" "Cluster 79: Photoreceptor cells - Phototransduction" 15 "Nucleoplasm, Primary cilium tip, Flagellar centriole" "Cytosol, Connecting piece" "HPA007119: " "unprognostic (1.97e-2)" "unprognostic (3.19e-3)" "unprognostic (9.42e-2)" "unprognostic (3.75e-3)" "unprognostic (1.44e-1)" "unprognostic (5.79e-2)" "unprognostic (3.17e-1)" "unprognostic (1.24e-2)" "unprognostic (2.74e-1)" "unprognostic (2.69e-1)" "validated prognostic favorable (5.77e-10)" "validated prognostic favorable (1.58e-4)" "potential prognostic favorable (1.06e-4)" "unprognostic (2.78e-2)" "unprognostic (4.41e-2)" "unprognostic (2.04e-1)" "unprognostic (3.52e-3)" "unprognostic (4.02e-2)" "unprognostic (9.35e-2)" "unprognostic (8.48e-3)" "unprognostic (4.67e-3)" "unprognostic (8.95e-2)" "unprognostic (2.31e-1)" "unprognostic (5.89e-2)" "potential prognostic favorable (3.93e-4)" "unprognostic (7.50e-2)" "unprognostic (2.22e-1)" "unprognostic (6.91e-2)" "unprognostic (4.79e-1)" "unprognostic (4.05e-2)" "unprognostic (1.74e-1)" KIF3C ENSG00000084731 "Kinesin family member 3C" O14782 2 25926598-25982749 "Plasma proteins, Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 75.6" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 71.5;Brain inhibitory neurons: 62.7;Oligodendrocyte progenitor cells: 56.3;Other brain neurons: 67.6;Retinal ganglion cells: 243.4;Retinal horizontal cells: 90.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Colon - Colon enteroendocrine cells, Pituitary gland - Lactotropes, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 24: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 10 "unprognostic (1.89e-1)" "unprognostic (2.10e-1)" "unprognostic (5.96e-2)" "unprognostic (2.06e-3)" "unprognostic (3.27e-2)" "unprognostic (2.63e-1)" "unprognostic (2.70e-1)" "potential prognostic favorable (8.38e-4)" "unprognostic (1.23e-1)" "unprognostic (1.53e-2)" "unprognostic (1.19e-2)" "unprognostic (1.02e-1)" "potential prognostic unfavorable (5.40e-4)" "unprognostic (1.12e-3)" "unprognostic (2.31e-1)" "unprognostic (2.15e-3)" "unprognostic (8.59e-3)" "unprognostic (3.48e-1)" "unprognostic (7.27e-2)" "unprognostic (1.18e-1)" "unprognostic (2.54e-2)" "unprognostic (5.02e-2)" "unprognostic (1.79e-3)" "unprognostic (3.16e-2)" "unprognostic (2.58e-1)" "unprognostic (1.66e-1)" "unprognostic (5.11e-3)" "unprognostic (3.57e-2)" "unprognostic (2.32e-1)" "unprognostic (1.46e-1)" "unprognostic (1.42e-1)" KIF4A "FLJ12530, FLJ12655, FLJ14204, FLJ20631, HSA271784, KIF4, KIF4-G1, MRX100" ENSG00000090889 "Kinesin family member 4A" O95239 X 70290104-70420886 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "DNA-binding, Motor protein" "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 10.6;lymphoid tissue: 11.7" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 31.1;Enteric transient amplifying cells: 33.3;Ependymal cells: 42.8;Erythrocyte progenitors: 88.8;Extravillous trophoblasts: 25.1;Fallopian tube ciliated cells: 26.3;Hepatic stellate cells: 25.8;Megakaryocyte progenitors: 62.2;Monocyte progenitors: 107.6;Neutrophil progenitors: 53.6" "Cell type enriched" "Detected in many" 14 "ependymal cell: 52.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Pituitary gland - Thyrotropes, Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in some" "Low region specificity" "Detected in single" "HPA034745, HPA034746, HPA061583" Approved Approved "Nucleoplasm,Midbody,Acrosome,Equatorial segment,Mid piece,Principal piece" Yes Yes "Cluster 9: T-regs - Cell cycle regulation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 46: Brainstem - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 27: Non-specific - Cell proliferation" 15 "Nucleoplasm, Midbody" "Acrosome, Equatorial segment, Mid piece, Principal piece" "HPA034745: , HPA034746: , HPA061583: " "unprognostic (9.60e-3)" "unprognostic (1.99e-2)" "unprognostic (2.15e-1)" "unprognostic (4.48e-2)" "unprognostic (1.11e-1)" "unprognostic (2.05e-1)" "unprognostic (4.03e-1)" "unprognostic (9.23e-2)" "unprognostic (2.08e-1)" "potential prognostic unfavorable (8.60e-5)" "validated prognostic unfavorable (5.64e-8)" "validated prognostic unfavorable (2.40e-6)" "validated prognostic unfavorable (2.45e-7)" "validated prognostic unfavorable (1.01e-10)" "validated prognostic unfavorable (2.08e-4)" "validated prognostic unfavorable (3.22e-4)" "unprognostic (2.81e-2)" "unprognostic (7.69e-2)" "unprognostic (1.48e-1)" "unprognostic (3.75e-2)" "potential prognostic unfavorable (1.60e-6)" "unprognostic (1.84e-2)" "unprognostic (3.57e-2)" "unprognostic (3.64e-3)" "unprognostic (5.94e-2)" "unprognostic (9.73e-2)" "unprognostic (1.48e-2)" "unprognostic (1.49e-1)" "unprognostic (2.22e-2)" KIF4B ENSG00000226650 "Kinesin family member 4B" Q2VIQ3 5 155013755-155018141 "Plasma proteins, Predicted intracellular proteins" "DNA-binding, Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 33 "testis: 3.3" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 2.1;Early spermatids: 4.5;Late primary spermatocytes: 22.4;Late spermatids: 6.8" "Low cell type specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "HPA034745, HPA034746, HPA061583" Uncertain Approved "Nucleoplasm,Midbody,Acrosome,Equatorial segment,Mid piece,Principal piece" Yes NA "Cluster 57: Testis - Spermatogenesis" "Cluster 61: BICR 18 - Protein kinases" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 1 "Nucleoplasm, Midbody" "Acrosome, Equatorial segment, Mid piece, Principal piece" "HPA034745: , HPA034746: , HPA061583: " KIF5A "D12S1889, MY050, NKHC, SPG10" ENSG00000155980 "Kinesin family member 5A" Q12840 12 57546026-57586633 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Hydrolase, Isomerase, Motor protein" "Amyotrophic lateral sclerosis, Disease variant, Epilepsy, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 22 "brain: 1437.1" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 98.4;Brain inhibitory neurons: 87.3;Cardiomyocytes: 100.4;Corticotrophs: 41.3;Early spermatids: 51.6;Epicardial cells: 36.4;Late spermatids: 60.3;Other brain neurons: 124.9;Retinal bipolar cells: 43.3;Retinal ganglion cells: 104.3;Retinal horizontal cells: 54.1" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" 11 "Glioblastoma Multiforme (TCGA): 83.7;Testicular Germ Cell Tumor (TCGA): 23.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Neuroblastoma: 31.0" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Stomach - Fibroblasts, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004469, HPA073448" Enhanced Approved "Nucleoplasm,Plasma membrane,Mitotic spindle,Cytosol,Mid piece,Principal piece" Yes No "Cluster 33: Non-specific - ATP binding" "Cluster 78: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 19 "Nucleoplasm, Cytosol" "Plasma membrane, Mitotic spindle, Mid piece, Principal piece" "HPA004469: , HPA073448: " "unprognostic (1.18e-1)" "unprognostic (7.15e-2)" "unprognostic (3.24e-1)" "unprognostic (4.02e-2)" "unprognostic (8.46e-2)" "unprognostic (6.95e-2)" "unprognostic (3.45e-2)" "potential prognostic favorable (7.58e-5)" "unprognostic (1.02e-1)" "unprognostic (1.08e-1)" "unprognostic (1.19e-1)" "unprognostic (1.40e-2)" "unprognostic (1.50e-1)" "unprognostic (3.43e-2)" "unprognostic (3.76e-3)" "unprognostic (3.55e-2)" "unprognostic (5.43e-3)" "unprognostic (1.33e-1)" "unprognostic (4.76e-2)" "unprognostic (1.06e-1)" "unprognostic (2.34e-1)" "unprognostic (1.74e-3)" "unprognostic (2.56e-2)" "unprognostic (4.56e-1)" "unprognostic (8.52e-3)" KIF5B "KNS, KNS1, uKHC" ENSG00000170759 "Kinesin family member 5B" P33176 10 32009015-32056425 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Motor protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009846, HPA037589, HPA037590" Approved Supported "Centriolar satellite,Cytosol,End piece" NA Yes 140000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 62: Smooth muscle cells - Muscle contraction" 82 "Centriolar satellite, Cytosol" "End piece" "CAB009846: , HPA037589: , HPA037590: " "unprognostic (1.28e-1)" "unprognostic (5.29e-3)" "unprognostic (1.33e-1)" "unprognostic (2.11e-1)" "unprognostic (1.41e-1)" "unprognostic (1.42e-1)" "unprognostic (1.69e-2)" "potential prognostic favorable (1.39e-4)" "unprognostic (8.89e-2)" "unprognostic (1.54e-2)" "potential prognostic favorable (4.24e-5)" "unprognostic (1.33e-1)" "unprognostic (1.10e-1)" "unprognostic (6.32e-3)" "unprognostic (3.43e-2)" "unprognostic (2.06e-1)" "unprognostic (9.68e-2)" "unprognostic (1.68e-1)" "unprognostic (3.33e-1)" "unprognostic (7.32e-2)" "unprognostic (1.06e-3)" "unprognostic (1.64e-2)" "unprognostic (1.39e-1)" "unprognostic (2.28e-1)" "unprognostic (2.50e-1)" "unprognostic (7.37e-2)" "unprognostic (2.06e-1)" "unprognostic (6.63e-2)" "unprognostic (4.37e-1)" "unprognostic (1.64e-2)" "unprognostic (2.68e-1)" KIF5C NKHC2 ENSG00000168280 "Kinesin family member 5C" O60282 2 148875227-149026759 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Transport "Hydrolase, Motor protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 51.8" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 375.2;Brain inhibitory neurons: 290.2;Early spermatids: 652.9;Ependymal cells: 181.2;Lactotrophs: 158.1;Late spermatids: 878.4;Oligodendrocyte progenitor cells: 188.5;Oligodendrocytes: 271.5;Other brain neurons: 210.2;Prostatic glandular cells: 246.9;Retinal amacrine cells: 281.6;Retinal bipolar cells: 164.4;Sertoli cells: 275.8" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Glioblastoma Multiforme (TCGA): 7.5;Prostate Adenocarcinoma (TCGA): 9.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "Neuroblastoma: 39.6" "Pituitary gland - Somatotropes, Prostate - Prostate glandular cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035210, HPA062272" Enhanced Uncertain "Cytosol,Equatorial segment,Connecting piece" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 34: Non-specific - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 30 "Cytosol, Equatorial segment, Connecting piece" "HPA035210: , HPA062272: " "unprognostic (1.02e-1)" "unprognostic (1.27e-1)" "unprognostic (2.98e-3)" "unprognostic (1.33e-1)" "unprognostic (5.43e-2)" "unprognostic (9.68e-2)" "unprognostic (3.56e-1)" KIF6 "C6orf102, dJ1043E3.1, dJ137F1.4, dJ188D3.1, DKFZp451I2418, MGC33317" ENSG00000164627 "Kinesin family member 6" Q6ZMV9 6 39329990-39725408 "Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.7;fallopian tube: 3.6;testis: 4.9" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 134.8;Ependymal cells: 454.0;Epididymal efferent duct ciliated cells: 81.8;Fallopian tube ciliated cells: 158.9;Oligodendrocytes: 325.1;Respiratory ciliated cells: 321.7;Rod photoreceptor cells: 85.4;Thyrotrophs: 85.6" "Cell type enhanced" "Detected in all" "ependymal cell: 477.7;oligodendrocyte: 443.9" "Group enriched" "Detected in some" 4 "Glioblastoma Multiforme (TCGA): 3.5;Skin Cutaneous Melanoma (TCGA): 3.9;Uterine Corpus Endometrial Carcinoma (TCGA): 1.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "skin cancer: 9.6" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA038811, HPA058624" Enhanced Approved "Nucleoplasm,Centrosome,Basal body,Cytosol" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 34: Ciliated cells - Cilia assembly & function" 1 "Centrosome, Basal body" "Nucleoplasm, Cytosol" "HPA038811: , HPA058624: " "unprognostic (1.27e-1)" "unprognostic (1.06e-1)" "unprognostic (2.42e-1)" "unprognostic (2.76e-1)" "unprognostic (1.07e-1)" "unprognostic (1.29e-1)" "unprognostic (8.76e-2)" KIF7 JBTS12 ENSG00000166813 "Kinesin family member 7" Q2M1P5 15 89608789-89663086 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Motor protein, Repressor" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Intellectual disability, Joubert syndrome, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 37.4;Astrocytes: 27.6;Fibro-adipogenic progenitors: 26.3" "Cell type enhanced" "Detected in many" "astrocyte: 31.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA043145 Approved Supported "Nucleoli fibrillar center,Primary cilium,Primary cilium tip,Cytosol" NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 89: Adipocytes - Lipid metabolism" 18 "Primary cilium, Primary cilium tip" "Nucleoli fibrillar center, Cytosol" "HPA043145: " "unprognostic (3.13e-1)" "unprognostic (5.07e-2)" "unprognostic (3.13e-1)" "unprognostic (1.08e-2)" "unprognostic (1.15e-2)" "unprognostic (5.07e-1)" "unprognostic (1.07e-1)" "unprognostic (2.76e-2)" "unprognostic (3.87e-3)" "unprognostic (1.45e-1)" "unprognostic (5.74e-3)" "potential prognostic unfavorable (9.05e-5)" "unprognostic (2.00e-1)" "unprognostic (1.32e-1)" "unprognostic (1.27e-3)" "unprognostic (1.33e-1)" "unprognostic (1.41e-2)" "unprognostic (3.04e-2)" "unprognostic (4.89e-2)" "unprognostic (2.39e-1)" "unprognostic (1.15e-1)" "unprognostic (8.13e-3)" "unprognostic (4.99e-2)" "unprognostic (2.34e-1)" "unprognostic (7.00e-2)" "unprognostic (1.07e-2)" "unprognostic (2.51e-1)" KIF9 MGC104186 ENSG00000088727 "Kinesin family member 9" Q9HAQ2 3 47227998-47283451 "Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 107.2;testis: 60.4" "Cell type enhanced" "Detected in many" "Early spermatids: 637.2;Endometrial ciliated cells: 460.6;Epididymal efferent duct ciliated cells: 753.0;Fallopian tube ciliated cells: 455.4;Late primary spermatocytes: 1062.5;Respiratory ciliated cells: 378.8" "Cell type enhanced" "Detected in all" "ependymal cell: 154.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022031, HPA022033, HPA030429" Approved Approved "Primary cilium,Primary cilium tip,Cytosol,Mid piece" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 107: Ciliated cells - Cilia assembly & function" 44 "Primary cilium, Primary cilium tip, Cytosol" "Mid piece" "HPA022031: , HPA022033: , HPA030429: " "unprognostic (6.13e-2)" "unprognostic (9.40e-2)" "unprognostic (1.77e-2)" "potential prognostic favorable (3.51e-7)" "unprognostic (3.71e-1)" "unprognostic (1.60e-2)" "unprognostic (1.54e-2)" "potential prognostic unfavorable (7.78e-4)" "unprognostic (4.69e-2)" "potential prognostic unfavorable (2.25e-4)" "validated prognostic favorable (1.79e-4)" "validated prognostic favorable (1.28e-4)" "potential prognostic favorable (4.19e-5)" "potential prognostic unfavorable (3.20e-4)" "unprognostic (8.76e-2)" "unprognostic (1.43e-1)" "unprognostic (2.31e-1)" "unprognostic (4.07e-1)" "unprognostic (1.52e-1)" "unprognostic (2.27e-2)" "unprognostic (7.27e-2)" "unprognostic (3.55e-2)" "unprognostic (1.28e-1)" "unprognostic (1.08e-1)" "unprognostic (4.02e-3)" "unprognostic (7.37e-3)" "unprognostic (2.48e-1)" "unprognostic (9.64e-3)" "unprognostic (1.18e-1)" "unprognostic (7.93e-2)" "unprognostic (3.34e-2)" KIFAP3 "FLA3, KAP-1, KAP3, SMAP" ENSG00000075945 "Kinesin associated protein 3" Q92845 1 169921326-170085208 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 319.2;Platelets: 395.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023738, HPA023742" Supported Approved "Nucleoplasm,Microtubules,Basal body" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 109: Neurons - Neuronal signaling" 39 "Microtubules, Basal body" Nucleoplasm "HPA023738: , HPA023742: " "unprognostic (3.53e-2)" "unprognostic (5.95e-2)" "unprognostic (1.93e-2)" "unprognostic (5.75e-2)" "unprognostic (1.00e-1)" "unprognostic (1.48e-1)" "unprognostic (9.43e-2)" "unprognostic (9.56e-2)" "unprognostic (3.51e-1)" "unprognostic (3.25e-2)" "potential prognostic favorable (3.55e-5)" "unprognostic (2.51e-3)" "unprognostic (4.22e-2)" "unprognostic (3.98e-3)" "unprognostic (3.68e-1)" "unprognostic (2.14e-1)" "unprognostic (2.28e-1)" "unprognostic (7.81e-3)" "unprognostic (3.75e-2)" "unprognostic (2.15e-2)" "potential prognostic unfavorable (6.68e-5)" "unprognostic (1.14e-1)" "unprognostic (5.85e-2)" "unprognostic (1.68e-1)" "unprognostic (2.91e-1)" "unprognostic (7.65e-2)" "unprognostic (1.28e-2)" "unprognostic (7.08e-3)" "unprognostic (4.66e-2)" "unprognostic (1.45e-2)" "unprognostic (3.70e-1)" KIFBP "DKFZP586B0923, KBP, KIAA1279, KIF1BP, TTC20" ENSG00000198954 "Kinesin family binding protein" Q96EK5 10 68988803-69043544 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Hirschsprung disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 124.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035538, HPA035539" Uncertain NA NA 16000 "Cluster 33: Non-specific - ATP binding" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 49 "HPA035538: , HPA035539: " "unprognostic (1.74e-3)" "unprognostic (4.38e-3)" "unprognostic (9.77e-3)" "unprognostic (2.22e-1)" "unprognostic (2.34e-3)" "unprognostic (8.04e-2)" "potential prognostic favorable (1.79e-4)" "unprognostic (1.72e-3)" "unprognostic (2.12e-2)" "potential prognostic favorable (3.25e-9)" "unprognostic (7.09e-2)" "unprognostic (6.85e-2)" "unprognostic (6.47e-3)" "unprognostic (4.74e-2)" "unprognostic (2.89e-1)" "unprognostic (1.93e-1)" "unprognostic (1.08e-2)" "unprognostic (1.05e-1)" "unprognostic (2.49e-3)" "unprognostic (1.79e-1)" "unprognostic (6.33e-3)" "unprognostic (8.34e-2)" "unprognostic (2.03e-1)" "unprognostic (1.09e-1)" "unprognostic (1.59e-1)" "unprognostic (9.61e-2)" "unprognostic (1.26e-1)" "unprognostic (4.23e-1)" "unprognostic (5.40e-2)" KIFC1 "HSET, KNSL2" ENSG00000237649 "Kinesin family member C1" Q9BW19 6 33391823-33409896 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 37.4;lymphoid tissue: 44.2" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 8.9;Early spermatids: 18.6;Enteric transient amplifying cells: 17.1;Erythrocyte progenitors: 23.4;Extravillous trophoblasts: 24.5;Hofbauer cells: 11.2;Megakaryocyte progenitors: 19.6;Migrating cytotrophoblasts: 16.8;Monocyte progenitors: 23.4;Paneth cells: 15.5" "Cell type enhanced" "Detected in some" "fibroblast: 2.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "T-reg: 1.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Breast - Breast glandular cells, Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" "HPA055997, HPA062674" Enhanced Approved "Primary cilium,Centrosome,Basal body" NA Yes "Cluster 5: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 29: Forebrain - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 27: Non-specific - Cell proliferation" 10 Centrosome "Primary cilium, Basal body" "HPA055997: , HPA062674: " "unprognostic (1.70e-2)" "unprognostic (2.21e-2)" "unprognostic (4.81e-2)" "unprognostic (7.93e-2)" "unprognostic (1.91e-1)" "unprognostic (8.37e-2)" "unprognostic (1.46e-1)" "unprognostic (6.89e-3)" "unprognostic (1.17e-1)" "unprognostic (3.61e-3)" "potential prognostic unfavorable (2.39e-6)" "unprognostic (6.05e-3)" "potential prognostic unfavorable (1.53e-8)" "validated prognostic unfavorable (4.08e-7)" "validated prognostic unfavorable (3.01e-7)" "validated prognostic unfavorable (7.66e-5)" "validated prognostic unfavorable (4.60e-4)" "unprognostic (1.16e-1)" "unprognostic (6.57e-3)" "unprognostic (2.39e-1)" "unprognostic (5.23e-2)" "potential prognostic unfavorable (3.61e-4)" "unprognostic (3.21e-1)" "unprognostic (1.82e-2)" "unprognostic (6.05e-2)" "unprognostic (2.62e-1)" "unprognostic (1.16e-2)" "unprognostic (2.92e-2)" "unprognostic (1.99e-1)" "unprognostic (2.88e-1)" "unprognostic (1.50e-1)" KIFC2 ENSG00000167702 "Kinesin family member C2" Q96AC6 8 144466043-144474202 "Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 214.8" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 68.7;Brain inhibitory neurons: 67.4;Other brain neurons: 48.8;Proximal tubule cells: 63.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029264 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 2: Non-specific - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 2: Cerebellar granular cells - Neuronal signaling" Nucleoplasm Cytosol "HPA029264: " "unprognostic (7.92e-3)" "unprognostic (1.61e-1)" "unprognostic (1.66e-1)" "potential prognostic unfavorable (3.16e-4)" "unprognostic (3.68e-2)" "unprognostic (6.26e-2)" "unprognostic (8.65e-2)" "unprognostic (1.08e-1)" "unprognostic (2.03e-1)" "unprognostic (1.79e-1)" "potential prognostic unfavorable (1.60e-5)" "unprognostic (1.34e-2)" "unprognostic (7.74e-2)" "unprognostic (6.49e-3)" "unprognostic (2.99e-1)" "unprognostic (6.53e-2)" "unprognostic (1.96e-1)" "unprognostic (2.05e-1)" "unprognostic (9.49e-2)" "unprognostic (4.55e-2)" "unprognostic (1.61e-3)" "unprognostic (3.03e-2)" "unprognostic (5.39e-3)" "unprognostic (6.87e-2)" "unprognostic (1.66e-1)" "unprognostic (1.50e-1)" "unprognostic (1.05e-1)" "unprognostic (4.76e-2)" "unprognostic (3.16e-2)" "unprognostic (3.42e-2)" "unprognostic (3.44e-2)" KIFC3 ENSG00000140859 "Kinesin family member C3" Q9BVG8 16 57758217-57863053 "Cancer-related genes, Predicted intracellular proteins" "Motor protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 168.1" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 594.1;Enterocytes: 295.0;Esophageal apical cells: 605.2;Late spermatids: 639.4;Loop of henle epithelial cells: 289.8;Platelets: 268.0;Proximal tubule cells: 402.6;Rod photoreceptor cells: 1050.4" "Cell type enhanced" "Detected in all" "midbrain-derived inhibitory: 200.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021240 Uncertain NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 72: Kidney - Transmembrane transport" "Cluster 9: Non-specific - Receptor signaling" "Cluster 72: Neuronal - Signal transduction" "Cluster 79: Photoreceptor cells - Phototransduction" 75 "HPA021240: " "unprognostic (1.40e-1)" "unprognostic (2.35e-1)" "unprognostic (4.77e-2)" "unprognostic (8.23e-3)" "unprognostic (2.30e-2)" "unprognostic (2.36e-1)" "unprognostic (7.68e-3)" "unprognostic (1.02e-1)" "unprognostic (2.90e-1)" "unprognostic (1.92e-1)" "unprognostic (4.68e-3)" "unprognostic (1.25e-3)" "unprognostic (1.68e-2)" "unprognostic (1.76e-2)" "unprognostic (1.60e-1)" "unprognostic (4.30e-1)" "unprognostic (3.30e-1)" "unprognostic (1.43e-2)" "unprognostic (1.95e-1)" "unprognostic (1.69e-2)" "unprognostic (2.73e-1)" "unprognostic (2.66e-2)" "potential prognostic unfavorable (1.64e-5)" "unprognostic (1.14e-1)" "unprognostic (9.17e-2)" "unprognostic (2.10e-1)" "unprognostic (6.10e-2)" "unprognostic (4.74e-2)" "unprognostic (6.98e-2)" "unprognostic (9.92e-2)" "unprognostic (9.34e-2)" KIN "KIN17, Rts2" ENSG00000151657 "Kin17 DNA and RNA binding protein" O60870 10 7750962-7787993 "Essential proteins, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, DNA replication, Host-virus interaction, mRNA processing, Stress response" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016339, HPA070369" Supported Nucleoplasm,Cytosol NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 49: Non-specific - Transcription" "Cluster 2: Neurons - Nucleosome" "Cluster 52: Non-specific - Mitochondria" "Cluster 7: Non-specific - Transcription" 7 Nucleoplasm Cytosol "CAB016339: , HPA070369: " "unprognostic (5.06e-3)" "unprognostic (1.03e-3)" "unprognostic (1.44e-1)" "unprognostic (2.75e-2)" "unprognostic (3.12e-3)" "unprognostic (1.51e-1)" "unprognostic (2.21e-2)" "potential prognostic favorable (2.04e-5)" "unprognostic (1.55e-1)" "unprognostic (2.70e-3)" "unprognostic (1.33e-1)" "unprognostic (7.01e-2)" "unprognostic (1.68e-2)" "unprognostic (9.15e-3)" "unprognostic (3.48e-3)" "unprognostic (2.49e-1)" "unprognostic (5.97e-2)" "unprognostic (3.20e-2)" "unprognostic (2.33e-1)" "unprognostic (9.12e-2)" "unprognostic (1.42e-3)" "unprognostic (9.47e-2)" "potential prognostic unfavorable (6.11e-4)" "unprognostic (2.65e-2)" "unprognostic (3.15e-2)" "unprognostic (1.04e-1)" "unprognostic (1.59e-1)" "unprognostic (1.67e-1)" "unprognostic (3.73e-1)" "unprognostic (4.47e-1)" "unprognostic (3.73e-1)" KIR2DL1 "47.11, CD158A, cl-42, nkat1, p58.1" ENSG00000125498 "Killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1" P43626 19 54769793-54784322 "CD markers, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.9" "Cell type enriched" "Detected in single" 18 "NK-cells: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - NK-cells (Lung)" NA NA "Cluster 5: Spleen - Immune response" "Cluster 70: DU4475 - Unknown function" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 5 KIR2DL3 "CD158B2, cl-6, nkat2, nkat2a, nkat2b, p58" ENSG00000243772 "Killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3" P43628 19 54738513-54753052 "CD markers, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "NK-cell: 1.4" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Lung - NK-cells (Lung)" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 70: DU4475 - Unknown function" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 56 "unprognostic (6.44e-2)" KIR2DL4 "103AS, 15.212, CD158D" ENSG00000189013 "Killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4" Q99706 19 54803610-54814517 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "lymphoid tissue: 4.3" "Cell type enriched" "Detected in single" 17 "NK-cells: 14.9" "Cell type enriched" "Detected in single" 15 "leukocyte: 3.4" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 80 "NK-cell: 8.0" "Lineage enriched" "Detected in single" 80 "NK-cells: 8.0" "Not detected" "Not detected" "Lung - NK-cells (Lung)" "Intracellular and membrane" Receptor NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 8 "unprognostic (2.68e-1)" KIR2DS4 "CD158I, cl-39, KKA3, nkat8" ENSG00000221957 "Killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 4" 19 54832676-54848569 "Predicted secreted proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 31 "NK-cells: 3.1" "Cell type enriched" "Detected in single" 49 "leukocyte: 4.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - NK-cells (Lung)" "Secreted to blood" NA NA "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" KIR3DL1 "AMB11, CD158E1, CD158e1/2, CD158e2, cl-11, cl-2, KIR, nkat3, NKB1, NKB1B" ENSG00000167633 "Killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1" P43629 19 54816468-54830778 "CD markers, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.4" "Cell type enriched" "Detected in some" 5 "NK-cells: 5.9" "Cell type enriched" "Detected in single" 89 "leukocyte: 9.0" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 5 "gdT-cell: 1.8" "Lineage enriched" "Detected in single" 5 "T-cells: 1.8" "Not detected" "Not detected" "Lung - NK-cells (Lung)" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 102: Non-specific - Mixed function" 5 KIR3DL2 "CD158K, cl-5, nkat4, nkat4a, nkat4b" ENSG00000240403 "Killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 2" P43630 19 54850443-54867207 "CD markers, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.8" "Cell type enriched" "Detected in single" 5 "NK-cells: 2.1" "Cell type enriched" "Detected in single" 22 "leukocyte: 3.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - T-cells, Lung - NK-cells (Lung), Minor Salivary Gland - Minor salivary glandular cells, Thyroid gland - T-cells" NA NA "Cluster 5: Spleen - Immune response" "Cluster 102: Non-specific - Mixed function" 1 "unprognostic (1.79e-2)" KIR3DL3 "CD158Z, KIR3DL7, KIR44, KIRC1" ENSG00000242019 "Killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 3" 19 54724442-54736632 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA KIRREL1 "KIRREL, NEPH1" ENSG00000183853 "Kirre like nephrin family adhesion molecule 1" Q96J84 1 157993273-158100262 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Podocytes: 774.6" "Cell type enhanced" "Detected in many" "pericyte: 230.7;vascular associated smooth muscle cell: 239.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030458 Approved NA NA 230000 "Cluster 75: Ovary - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 69: Skin cancer - ECM organization" "Cluster 57: Podocytes - Glomerular filtration" 11 "HPA030458: " "unprognostic (8.92e-2)" "unprognostic (1.80e-1)" "potential prognostic unfavorable (2.28e-4)" "unprognostic (7.06e-2)" "unprognostic (3.45e-1)" "unprognostic (1.25e-2)" "unprognostic (6.76e-2)" "unprognostic (3.05e-2)" "unprognostic (2.89e-2)" "unprognostic (2.75e-1)" "unprognostic (2.05e-1)" "unprognostic (1.20e-3)" "unprognostic (1.34e-1)" "unprognostic (2.89e-1)" "unprognostic (7.72e-3)" "unprognostic (2.43e-1)" "unprognostic (5.41e-2)" "unprognostic (1.48e-2)" "unprognostic (2.02e-1)" "unprognostic (9.28e-2)" "unprognostic (1.01e-1)" "unprognostic (1.50e-1)" "unprognostic (2.50e-1)" "potential prognostic favorable (8.70e-4)" "unprognostic (1.01e-2)" "unprognostic (5.29e-3)" "unprognostic (2.37e-1)" "unprognostic (1.29e-1)" "unprognostic (5.55e-2)" KIRREL2 "DKFZp564A1164, FILTRIN, MGC15718, NEPH3, NLG1" ENSG00000126259 "Kirre like nephrin family adhesion molecule 2" Q6UWL6 19 35855861-35867136 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "pancreas: 67.0" "Cell type enhanced" "Detected in some" "Endometrial glandular cells: 6.3;Endometrial luminal cells: 15.4;Endometrial secretory cells: 12.3;Epicardial cells: 27.3;Hofbauer cells: 6.8;Pancreatic acinar cells: 21.3;Pancreatic islet cells: 11.5;pDCs: 12.9;Retinal bipolar cells: 58.9;Retinal pigment epithelial cells: 29.8" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in some" "Pancreatic Adenocarcinoma (TCGA): 4.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Kidney - Podocytes, Pituitary gland - Somatotropes, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "HPA071587, HPA074326" Enhanced Supported "Centriolar satellite" "Intracellular and membrane" "No annotated function" NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 34: Non-specific - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 2 "Centriolar satellite" "HPA071587: , HPA074326: " "unprognostic (3.82e-1)" "unprognostic (5.41e-3)" "unprognostic (2.21e-1)" "unprognostic (1.74e-1)" "unprognostic (5.15e-2)" "unprognostic (2.41e-2)" "unprognostic (7.35e-3)" "unprognostic (2.60e-1)" KIRREL3 "KIAA1867, KIRRE, NEPH2" ENSG00000149571 "Kirre like nephrin family adhesion molecule 3" Q8IZU9 11 126423358-127003460 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 26.6" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 589.4;Brain inhibitory neurons: 767.4;Early spermatids: 253.7;Late primary spermatocytes: 173.6;Late spermatids: 412.7;Oligodendrocytes: 989.3;Other brain neurons: 218.7;Retinal amacrine cells: 550.9;Retinal bipolar cells: 347.0;Schwann cells: 224.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 4.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 12 "plasmacytoid DC: 8.3" "Lineage enriched" "Detected in single" 12 "dendritic cells: 8.3" "Cancer enhanced" "Detected in many" "Brain cancer: 6.9" "Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Minor Salivary Gland - Minor salivary gland ductal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053324 Enhanced "Intracellular and membrane" "No annotated function" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 6 "HPA053324: " "unprognostic (5.49e-2)" "unprognostic (2.99e-2)" "unprognostic (2.28e-1)" "unprognostic (2.85e-2)" "unprognostic (4.57e-2)" KISS1 ENSG00000170498 "KiSS-1 metastasis suppressor" Q15726 1 204190341-204196491 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Cancer-related genes, Disease variant, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 30 "placenta: 220.0" "Cell type enriched" "Detected in some" 40 "Syncytiotrophoblasts: 1419.6" "Cell type enhanced" "Detected in some" "cerebellar inhibitory: 2.6;deep-layer near-projecting: 2.4" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 25.5" "Region enriched" "Detected in many" 6 "hypothalamus: 19.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Adrenocortical cancer: 170.5" "Lung - Alveolar cells type 2, Prostate - Prostate basal glandular cells, Testis - Early spermatids, Testis - Late spermatids" "CAB017775, HPA035542" Enhanced Approved Vesicles "Secreted in female reproductive system" "No annotated function" NA NA 590000 "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 72: Neuronal - Signal transduction" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." 7 Vesicles "CAB017775: , HPA035542: " "unprognostic (1.10e-1)" "unprognostic (2.18e-1)" "unprognostic (7.83e-2)" "unprognostic (3.82e-2)" "unprognostic (4.92e-2)" "unprognostic (2.75e-1)" "unprognostic (3.31e-1)" "unprognostic (2.67e-2)" "potential prognostic unfavorable (1.05e-5)" "unprognostic (1.97e-1)" "unprognostic (1.67e-1)" "unprognostic (4.15e-2)" "unprognostic (5.57e-2)" "unprognostic (5.68e-3)" "unprognostic (1.12e-1)" "unprognostic (4.67e-2)" "potential prognostic unfavorable (3.43e-5)" "unprognostic (6.05e-2)" "unprognostic (2.70e-1)" "unprognostic (2.93e-1)" "unprognostic (4.78e-2)" "unprognostic (1.22e-1)" KISS1R "AXOR12, GPR54, HOT7T175" ENSG00000116014 "KISS1 receptor" Q969F8 19 917287-921005 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 3.5;pancreas: 1.3;pituitary gland: 1.0" "Group enriched" "Detected in some" 10 "Extravillous trophoblasts: 73.4;Pancreatic acinar cells: 105.6" "Cell type enhanced" "Detected in many" "deep-layer near-projecting: 11.1;splatter: 7.8" "Cancer enriched" "Detected in many" 5 "Kidney Renal Clear Cell Carcinoma (TCGA): 9.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 13.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA007156, HPA071913" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 24: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 3 "Plasma membrane" Vesicles "HPA007156: , HPA071913: " "unprognostic (2.20e-1)" "unprognostic (3.24e-1)" "unprognostic (4.25e-1)" "unprognostic (8.51e-3)" "unprognostic (5.59e-2)" "unprognostic (6.43e-3)" "unprognostic (3.67e-2)" "unprognostic (1.07e-2)" "unprognostic (7.77e-2)" KIT "C-Kit, CD117, PBT, SCFR" ENSG00000157404 "KIT proto-oncogene, receptor tyrosine kinase" P10721 4 54657267-54740783 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 79.2" "Cell type enhanced" "Detected in many" "Breast secretory cells: 230.0;Innate lymphoid cells: 512.9;Mast cells: 1765.7;Melanocytes: 649.5;Renal collecting duct intercalated cells: 569.2;Respiratory ionocytes: 396.2;Salivary ionocytes: 263.8;Tuft cells: 253.6" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 699.5;CGE interneuron: 325.6;midbrain-derived inhibitory: 571.8" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 143.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 16.1;eosinophil: 9.6;NK-cell: 11.1" "Group enriched" "Detected in many" 7 "granulocytes: 16.1;NK-cells: 11.1" "Cancer enhanced" "Detected in many" "Leukemia: 28.3" "Adipose subcutaneous - Mast cells, Lung - Mast cells, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003288, HPA004471, CAB068253, CAB072867, HPA073252" Enhanced Supported Supported "Nucleoli fibrillar center,Plasma membrane" NA NA 33000000 "Cluster 32: Basophils - Transcription" "Cluster 55: Breast - Lactation" "Cluster 35: Non-specific - DNA binding" "Cluster 49: HMC-1 - Innate immune response" "Cluster 58: Mast cells - Allergic inflammatory responses" 42 "Plasma membrane" "Nucleoli fibrillar center" "CAB003288: , CAB068253: , CAB072867: , HPA004471: , HPA073252: " "unprognostic (7.25e-2)" "unprognostic (1.24e-2)" "unprognostic (1.08e-1)" "unprognostic (3.57e-1)" "unprognostic (2.82e-1)" "unprognostic (4.48e-2)" "unprognostic (1.51e-1)" "unprognostic (1.08e-1)" "unprognostic (4.25e-2)" "unprognostic (1.60e-1)" "validated prognostic favorable (7.36e-5)" "validated prognostic favorable (6.08e-5)" "unprognostic (2.94e-1)" "unprognostic (7.19e-3)" "unprognostic (2.19e-3)" "unprognostic (1.04e-2)" "unprognostic (3.27e-2)" "unprognostic (1.38e-1)" "unprognostic (2.74e-1)" "unprognostic (1.04e-1)" "unprognostic (9.24e-2)" "potential prognostic favorable (3.33e-4)" "unprognostic (1.39e-2)" "unprognostic (8.07e-2)" "unprognostic (2.38e-3)" "unprognostic (7.41e-2)" "unprognostic (1.10e-2)" "unprognostic (3.71e-1)" KITLG "DFNA69, FPH2, Kitl, KL-1, MGF, SCF, SF, SLF" ENSG00000049130 "KIT ligand" P21583 12 88492793-88580851 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Cell adhesion" "Growth factor" "Cancer-related genes, Deafness, Disease variant, Non-syndromic deafness, Waardenburg syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 138.4;Bergmann glia: 155.4;Distal convoluted tubule cells: 272.0;Ependymal cells: 148.6;Papillary tip epithelial cells: 249.5;Renal collecting duct principal cells: 269.3;Renal connecting tubule cells: 521.1;Respiratory ionocytes: 188.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070395 Approved Approved Vesicles "Intracellular and membrane" "Growth factor" NA NA 190000 "Cluster 13: Lung - Secretion" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 32: Non-specific - Cell proliferation" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 3 Vesicles "HPA070395: " "unprognostic (4.45e-2)" "unprognostic (4.23e-2)" "unprognostic (2.73e-2)" "unprognostic (1.45e-1)" "unprognostic (2.78e-2)" "unprognostic (1.99e-1)" "unprognostic (2.78e-1)" "unprognostic (3.44e-1)" "unprognostic (9.96e-3)" "unprognostic (4.18e-2)" "validated prognostic favorable (2.07e-7)" "validated prognostic favorable (7.13e-4)" "unprognostic (9.80e-2)" "unprognostic (6.13e-2)" "unprognostic (4.32e-3)" "unprognostic (2.03e-2)" "unprognostic (3.89e-2)" "unprognostic (3.02e-1)" "unprognostic (1.04e-1)" "unprognostic (1.06e-1)" "potential prognostic unfavorable (5.87e-4)" "unprognostic (4.77e-3)" "unprognostic (7.47e-2)" "unprognostic (1.95e-1)" "unprognostic (2.60e-1)" "unprognostic (1.10e-1)" "unprognostic (2.30e-1)" "unprognostic (1.58e-2)" "unprognostic (4.45e-2)" "unprognostic (7.82e-2)" "unprognostic (3.67e-2)" KIZ "C20orf19, HT013, NCRNA00153, PLK1S1" ENSG00000088970 "Kizuna centrosomal protein" Q2M2Z5 20 21125983-21246622 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 290.4;Oligodendrocyte progenitor cells: 298.8;Renal collecting duct principal cells: 252.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 21: Testis - Mixed function" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 8 "unprognostic (4.98e-2)" "unprognostic (5.87e-2)" "unprognostic (5.69e-3)" "unprognostic (4.02e-1)" "unprognostic (1.64e-1)" "unprognostic (1.26e-1)" "unprognostic (2.48e-3)" "unprognostic (2.39e-1)" "unprognostic (6.34e-2)" "unprognostic (3.48e-2)" "unprognostic (1.28e-1)" "unprognostic (4.92e-3)" "unprognostic (2.74e-1)" "unprognostic (2.34e-2)" "unprognostic (1.87e-1)" "unprognostic (8.80e-3)" "unprognostic (1.10e-1)" "unprognostic (4.19e-3)" "unprognostic (3.94e-3)" "unprognostic (9.45e-3)" "unprognostic (3.11e-2)" "unprognostic (4.05e-2)" "unprognostic (1.46e-1)" "unprognostic (2.55e-2)" "unprognostic (1.50e-1)" "unprognostic (1.11e-1)" "unprognostic (1.46e-1)" "unprognostic (1.04e-2)" "unprognostic (6.83e-2)" KL KLA ENSG00000133116 Klotho Q9UEF7 13 33016423-33066143 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Glycosidase, Hormone, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "kidney: 120.2;parathyroid gland: 127.3" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 276.1;Distal convoluted tubule cells: 308.7;Prostatic glandular cells: 69.5;Proximal tubule cells: 98.5;Renal connecting tubule cells: 99.5" "Cell type enriched" "Detected in many" 7 "choroid plexus epithelial cell: 218.8" "Group enriched" "Detected in many" 6 "Kidney Renal Clear Cell Carcinoma (TCGA): 26.7;Kidney Renal Papillary Cell Carcinoma (TCGA): 28.3;Prostate Adenocarcinoma (TCGA): 8.3" "Region enriched" "Detected in many" 11 "choroid plexus: 102.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 2.0;Kidney cancer: 4.3" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Minor Salivary Gland - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Spleen - Endothelial cells, Stomach - Chief cells, Thyroid gland - Endothelial cells" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basal ganglia: 13.9;cerebral cortex: 7.1;hippocampal formation: 7.6;medulla oblongata: 4.3" "Secreted to blood" Hormone NA NA 510000 "Cluster 72: Kidney - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 101: Choroid plexus epithelial cells - Ion transport" "unprognostic (1.97e-1)" "unprognostic (1.87e-3)" "potential prognostic unfavorable (8.31e-4)" "unprognostic (1.43e-1)" "potential prognostic favorable (5.65e-13)" "unprognostic (3.85e-3)" "unprognostic (2.14e-3)" "unprognostic (5.05e-3)" "unprognostic (1.42e-2)" "unprognostic (1.66e-3)" "unprognostic (3.36e-2)" "unprognostic (2.00e-1)" "unprognostic (9.12e-3)" KLB ENSG00000134962 "Klotho beta" Q86Z14 4 39406930-39451533 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 18.4;liver: 16.6" "Cell type enhanced" "Detected in many" "Adipocytes: 193.2;Goblet cells: 22.0;Hepatocytes: 54.1;Late primary spermatocytes: 73.8;Neuroendocrine cells: 24.9;Pancreatic acinar cells: 32.8" "Cell type enhanced" "Detected in some" "splatter: 5.1" "Cancer enriched" "Detected in some" 12 "Liver Hepatocellular Carcinoma (TCGA): 14.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 8.3" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Minor Salivary Gland - Adipocytes (Minor salivary gland), Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA021136 Uncertain Approved "Mid piece,Principal piece" NA NA 220000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 18: Liver cancer - Metabolism" "Cluster 89: Adipocytes - Lipid metabolism" 1 "Mid piece, Principal piece" "HPA021136: " "unprognostic (1.85e-2)" "unprognostic (1.46e-1)" "unprognostic (4.63e-1)" "unprognostic (2.76e-2)" "unprognostic (2.88e-3)" "unprognostic (6.10e-3)" "unprognostic (4.73e-2)" "unprognostic (7.50e-2)" KLC1 "hKLC1B, hKLC1G, hKLC1J, hKLC1N, hKLC1P, hKLC1R, hKLC1S, KLC, KNS2, KNS2A" ENSG00000126214 "Kinesin light chain 1" Q07866 14 103561896-103714249 "Predicted intracellular proteins" "Cell adhesion, Host-virus interaction" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 513.1" "Cell type enhanced" "Detected in all" "Bergmann glia: 220.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009798, HPA044617, HPA052450" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol,Acrosome,Equatorial segment" NA NA 6900 "Cluster 25: Non-specific - Unknown function" "Cluster 27: Cerebellum - Synaptic function" "Cluster 24: Neurons - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 22: Non-specific - Basic cellular functions" 43 "Plasma membrane, Acrosome, Equatorial segment" "Nucleoplasm, Cytosol" "CAB009798: , HPA044617: , HPA052450: " "unprognostic (4.65e-1)" "unprognostic (2.11e-3)" "unprognostic (8.72e-2)" "unprognostic (8.10e-2)" "unprognostic (2.55e-1)" "unprognostic (1.53e-1)" "unprognostic (1.09e-1)" "unprognostic (5.40e-3)" "unprognostic (7.15e-3)" "unprognostic (3.98e-1)" "unprognostic (6.92e-3)" "unprognostic (7.28e-3)" "unprognostic (5.11e-2)" "unprognostic (2.57e-3)" "unprognostic (1.92e-1)" "unprognostic (6.45e-2)" "unprognostic (3.39e-1)" "unprognostic (8.90e-2)" "unprognostic (1.85e-1)" "unprognostic (1.76e-1)" "unprognostic (1.35e-1)" "unprognostic (6.91e-3)" "unprognostic (1.19e-2)" "unprognostic (2.80e-2)" "unprognostic (1.42e-1)" "unprognostic (4.06e-3)" "unprognostic (2.64e-1)" "unprognostic (1.11e-2)" "unprognostic (2.86e-1)" "unprognostic (5.54e-2)" "unprognostic (2.68e-1)" KLC2 FLJ12387 ENSG00000174996 "Kinesin light chain 2" Q9H0B6 11 66257294-66267860 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Motor protein" "Hereditary spastic paraplegia, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 147.1" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 42.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040416, HPA040434" Approved Supported "Nucleoplasm,Plasma membrane,Mitochondria,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 27: Cerebellum - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 24: Non-specific - Unknown function" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" 50 "Plasma membrane, Cytosol" "Nucleoplasm, Mitochondria" "HPA040416: , HPA040434: " "unprognostic (1.05e-1)" "unprognostic (3.80e-2)" "unprognostic (1.81e-1)" "unprognostic (6.82e-3)" "unprognostic (1.95e-1)" "unprognostic (1.00e-2)" "unprognostic (2.35e-1)" "unprognostic (6.31e-2)" "potential prognostic unfavorable (5.87e-4)" "unprognostic (1.85e-3)" "unprognostic (1.26e-1)" "unprognostic (2.52e-2)" "unprognostic (1.07e-1)" "unprognostic (1.57e-3)" "unprognostic (2.73e-1)" "unprognostic (1.50e-2)" "unprognostic (7.82e-2)" "unprognostic (1.01e-1)" "unprognostic (4.58e-3)" "unprognostic (3.82e-1)" "unprognostic (3.57e-1)" "unprognostic (2.88e-2)" "unprognostic (8.58e-3)" "unprognostic (1.32e-3)" "unprognostic (1.80e-2)" "unprognostic (1.70e-1)" "unprognostic (2.84e-2)" "unprognostic (1.69e-1)" "unprognostic (1.59e-1)" "unprognostic (1.38e-2)" "unprognostic (2.45e-1)" KLC3 "KLC2L, KLCt, KNS2B" ENSG00000104892 "Kinesin light chain 3" Q6P597 19 45333434-45351520 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 24.9;skin 1: 99.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 119.6;Breast myoepithelial cells: 45.6;Epididymal basal cells: 40.2;Esophageal apical cells: 75.7;Esophageal basal cells: 59.9;Esophageal suprabasal cells: 100.5;Ocular epithelial cells: 32.2;Suprabasal keratinocytes: 174.3" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 36.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Pancreas - Ductal cells, Pituitary gland - Gonadotropes, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other), Spleen - Erythrocytes, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA052797, HPA056508" Approved Approved "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 37: Skin - Keratinization" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 26: Keratinocytes - Keratinization" 54 "Centriolar satellite, Cytosol" Nucleoplasm "HPA052797: , HPA056508: " "unprognostic (1.11e-1)" "unprognostic (3.60e-2)" "unprognostic (8.36e-2)" "unprognostic (3.27e-1)" "unprognostic (1.65e-2)" "unprognostic (8.40e-2)" "unprognostic (5.04e-2)" "unprognostic (1.36e-1)" "unprognostic (6.72e-2)" "unprognostic (1.43e-1)" "unprognostic (8.89e-2)" "unprognostic (1.24e-1)" "potential prognostic unfavorable (5.62e-4)" "unprognostic (2.60e-1)" "unprognostic (1.11e-1)" "unprognostic (1.37e-1)" "unprognostic (2.12e-2)" "unprognostic (8.17e-2)" "unprognostic (7.89e-2)" "unprognostic (4.32e-2)" "potential prognostic unfavorable (3.41e-4)" "unprognostic (5.83e-2)" "unprognostic (1.46e-1)" "unprognostic (1.30e-3)" "unprognostic (3.43e-1)" "unprognostic (1.79e-1)" "unprognostic (1.35e-2)" "unprognostic (4.46e-1)" "unprognostic (2.38e-3)" KLC4 "bA387M24.3, KNSL8" ENSG00000137171 "Kinesin light chain 4" Q9NSK0 6 43040777-43075095 "Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 159.7;Colonocytes: 103.6;Enterocytes: 177.2;Hepatocytes: 106.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030168, HPA030169" Enhanced Uncertain Mitochondria,Cytosol NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 77: Intestine - Digestion" "Cluster 37: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 58 Mitochondria Cytosol "HPA030168: , HPA030169: " "unprognostic (3.36e-2)" "unprognostic (1.31e-1)" "unprognostic (3.57e-1)" "unprognostic (1.02e-1)" "unprognostic (3.32e-2)" "unprognostic (9.83e-2)" "unprognostic (3.17e-2)" "unprognostic (2.83e-3)" "unprognostic (1.09e-2)" "unprognostic (3.60e-1)" "validated prognostic favorable (1.08e-8)" "validated prognostic favorable (9.89e-5)" "potential prognostic favorable (9.64e-5)" "unprognostic (1.24e-2)" "unprognostic (2.67e-1)" "unprognostic (1.50e-2)" "unprognostic (1.12e-1)" "unprognostic (3.57e-1)" "unprognostic (2.60e-1)" "unprognostic (2.72e-1)" "unprognostic (1.25e-1)" "unprognostic (1.08e-1)" "potential prognostic favorable (8.98e-4)" "unprognostic (9.76e-2)" "unprognostic (3.63e-2)" "unprognostic (3.50e-2)" "unprognostic (7.22e-3)" "unprognostic (2.14e-1)" "unprognostic (2.01e-1)" "unprognostic (1.56e-1)" "unprognostic (4.38e-2)" KLF1 EKLF ENSG00000105610 "KLF transcription factor 1" Q13351 19 12884422-12887201 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Congenital dyserythropoietic anemia, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "bone marrow: 38.8" "Group enriched" "Detected in some" 6 "Erythrocyte progenitors: 383.1;Erythrocytes: 124.8;Megakaryocyte-Erythroid progenitors: 146.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.9;non-classical monocyte: 1.2" "Lineage enriched" "Detected in single" 7 "monocytes: 1.9" "Cancer enriched" "Detected in single" 109 "Leukemia: 40.9" "Liver - Erythroid cells, Spleen - Erythrocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA051850 Enhanced Supported Nucleoplasm NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 15: Bone marrow - Innate immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 21 Nucleoplasm "HPA051850: " KLF10 "EGRA, TIEG, TIEG1" ENSG00000155090 "KLF transcription factor 10" Q13118 8 102648784-102655725 "Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial luminal cells: 266.7;Epididymal efferent duct absorptive cells: 355.4;Smooth muscle cells: 247.3" "Cell type enhanced" "Detected in many" "endothelial cell: 31.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 29: Forebrain - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 9 "unprognostic (3.59e-2)" "unprognostic (2.95e-2)" "unprognostic (5.65e-2)" "unprognostic (4.78e-3)" "unprognostic (8.40e-2)" "unprognostic (1.27e-1)" "potential prognostic unfavorable (4.66e-4)" "unprognostic (3.88e-3)" "unprognostic (2.72e-2)" "unprognostic (5.98e-2)" "potential prognostic favorable (1.75e-6)" "unprognostic (1.62e-3)" "unprognostic (6.72e-2)" "unprognostic (1.49e-1)" "unprognostic (4.43e-3)" "potential prognostic unfavorable (9.47e-4)" "unprognostic (2.91e-2)" "potential prognostic unfavorable (2.82e-5)" "unprognostic (1.15e-3)" "unprognostic (9.86e-3)" "unprognostic (7.88e-3)" "unprognostic (2.01e-2)" "unprognostic (8.50e-3)" "unprognostic (3.04e-1)" "unprognostic (2.71e-1)" "unprognostic (4.24e-2)" "unprognostic (4.87e-1)" "unprognostic (1.65e-2)" "unprognostic (1.48e-1)" "unprognostic (7.68e-3)" "unprognostic (1.67e-1)" KLF11 "FKLF, MODY7, TIEG2, Tieg3" ENSG00000172059 "KLF transcription factor 11" O14901 2 10042849-10054836 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 188.3;Suprabasal keratinocytes: 73.5" "Cell type enhanced" "Detected in many" "endothelial cell: 32.4;pericyte: 22.2;vascular associated smooth muscle cell: 24.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058276 Supported "Nucleoplasm,Nuclear bodies,Focal adhesion sites,Cytosol" Yes No "Cluster 40: Monocytes - Innate immune response" "Cluster 57: Testis - Spermatogenesis" "Cluster 15: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 167 Nucleoplasm "Nuclear bodies, Focal adhesion sites, Cytosol" "HPA058276: " "unprognostic (1.10e-2)" "unprognostic (5.54e-3)" "unprognostic (7.76e-3)" "unprognostic (3.31e-1)" "unprognostic (1.90e-1)" "unprognostic (3.24e-2)" "unprognostic (3.24e-3)" "unprognostic (2.29e-2)" "unprognostic (2.79e-3)" "unprognostic (1.56e-1)" "potential prognostic favorable (2.81e-7)" "unprognostic (4.56e-2)" "unprognostic (3.94e-1)" "unprognostic (1.13e-2)" "unprognostic (3.76e-1)" "unprognostic (9.97e-2)" "unprognostic (1.62e-1)" "unprognostic (8.60e-2)" "unprognostic (4.42e-2)" "unprognostic (7.37e-2)" "unprognostic (2.95e-1)" "unprognostic (3.28e-3)" "unprognostic (1.34e-1)" "unprognostic (3.50e-2)" "unprognostic (1.24e-1)" "unprognostic (1.05e-2)" "unprognostic (2.04e-1)" "unprognostic (2.21e-1)" "unprognostic (4.09e-1)" "unprognostic (4.18e-3)" "unprognostic (2.66e-2)" KLF12 "AP-2rep, AP2REP, HSPC122" ENSG00000118922 "KLF transcription factor 12" Q9Y4X4 13 73686089-74134404 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Myonuclei: 815.7;NK-cells: 691.4;T-cells: 703.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatocytes, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064146, HPA075652" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 1: T-cells - Unknown function" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 1: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" 40 Nucleoplasm Cytosol "HPA064146: , HPA075652: " "unprognostic (1.41e-2)" "unprognostic (8.61e-2)" "unprognostic (1.68e-1)" "unprognostic (1.30e-1)" "unprognostic (1.86e-2)" "unprognostic (1.88e-1)" "unprognostic (8.50e-2)" "unprognostic (7.04e-3)" "unprognostic (2.78e-1)" "unprognostic (1.80e-1)" "validated prognostic favorable (5.10e-7)" "validated prognostic favorable (5.77e-5)" "unprognostic (9.61e-2)" "unprognostic (6.53e-2)" "unprognostic (1.37e-2)" "unprognostic (2.68e-1)" "unprognostic (2.54e-1)" "unprognostic (6.22e-2)" "unprognostic (4.22e-1)" "unprognostic (4.01e-2)" "unprognostic (1.67e-1)" "unprognostic (1.13e-2)" "unprognostic (1.88e-1)" "unprognostic (1.22e-1)" "unprognostic (3.37e-1)" "unprognostic (1.44e-1)" "unprognostic (2.02e-2)" "unprognostic (1.39e-1)" "unprognostic (3.04e-1)" "unprognostic (2.80e-1)" "unprognostic (2.25e-1)" KLF13 "BTEB3, FKLF-2, NSLP1, RFLAT-1" ENSG00000169926 "KLF transcription factor 13" Q9Y2Y9 15 31326835-31435665 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 39.6;Loop of henle epithelial cells: 47.4;Oligodendrocytes: 76.4;Papillary tip epithelial cells: 45.8;Podocytes: 42.6;Proximal tubule cells: 96.2;Renal collecting duct intercalated cells: 66.6;Renal collecting duct principal cells: 54.7;Renal connecting tubule cells: 59.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 102: Non-specific - Mixed function" 5 "unprognostic (4.32e-3)" "unprognostic (6.04e-3)" "unprognostic (3.58e-1)" "unprognostic (1.18e-2)" "unprognostic (1.67e-1)" "unprognostic (1.47e-2)" "unprognostic (3.77e-2)" "potential prognostic favorable (6.93e-6)" "unprognostic (1.69e-2)" "unprognostic (1.58e-1)" "unprognostic (2.16e-2)" "unprognostic (1.94e-3)" "unprognostic (1.70e-1)" "unprognostic (7.70e-2)" "unprognostic (1.11e-1)" "unprognostic (4.20e-2)" "unprognostic (2.04e-1)" "unprognostic (1.88e-3)" "unprognostic (3.00e-2)" "unprognostic (9.64e-2)" "unprognostic (8.15e-3)" "unprognostic (2.85e-1)" "unprognostic (1.64e-1)" "unprognostic (1.74e-1)" "unprognostic (3.19e-1)" "unprognostic (6.06e-2)" "unprognostic (2.63e-3)" "unprognostic (7.43e-2)" "unprognostic (1.77e-1)" "unprognostic (9.57e-2)" "unprognostic (3.65e-1)" KLF14 BTEB5 ENSG00000266265 "KLF transcription factor 14" Q8TD94 7 130730697-130734207 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "adrenal gland: 1.0" "Cell type enhanced" "Detected in some" "Adipocytes: 1.7;Adrenal medulla cells: 10.6;Early spermatids: 4.4;Late primary spermatocytes: 2.5;Late spermatids: 5.5;Mesothelial cells: 1.5;Neutrophils: 4.3;Pituicytes/FSCs: 1.2;Smooth muscle cells: 1.9" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Skin Cutaneous Melanoma (TCGA): 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Rhabdoid: 1.0" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Spleen - Neutrophils_2" "Not detected" "Not detected" "Not detected" "Not detected" HPA044729 Uncertain NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 5: Rhabdoid - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" "HPA044729: " "unprognostic (8.76e-2)" KLF15 KKLF ENSG00000163884 "KLF transcription factor 15" Q9UIH9 3 126342635-126357408 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 88.7" "Cell type enhanced" "Detected in many" "Astrocytes: 31.7;Bergmann glia: 51.9;Breast lactating cells: 88.5;Hepatocytes: 70.8;Proximal tubule cells: 56.6;Schwann cells: 35.8;Thymic myoid cells: 65.3" "Cell type enhanced" "Detected in many" "astrocyte: 37.9;Bergmann glia: 59.6" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 42.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Skin - Macrophages, Spleen - Fibroblasts_2, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003286, HPA028866" Uncertain Supported "Nucleoplasm,Nuclear speckles,Vesicles" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 6: Non-specific - Immune response" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 59 "Nucleoplasm, Nuclear speckles" Vesicles "HPA003286: , HPA028866: " "unprognostic (5.36e-3)" "unprognostic (3.50e-3)" "unprognostic (2.76e-1)" "unprognostic (2.09e-1)" "unprognostic (6.13e-2)" "unprognostic (2.59e-1)" "unprognostic (2.85e-1)" "unprognostic (1.02e-1)" "potential prognostic favorable (4.82e-7)" "unprognostic (1.24e-2)" "unprognostic (3.53e-3)" "unprognostic (5.26e-2)" "unprognostic (3.07e-1)" "validated prognostic favorable (1.10e-4)" "validated prognostic favorable (1.68e-4)" "unprognostic (6.05e-2)" "unprognostic (1.98e-3)" "unprognostic (5.45e-2)" "unprognostic (4.46e-2)" "unprognostic (1.87e-2)" "unprognostic (6.41e-2)" "unprognostic (1.72e-1)" "unprognostic (6.83e-2)" "unprognostic (1.43e-2)" "unprognostic (1.24e-2)" "unprognostic (2.83e-1)" "unprognostic (1.16e-2)" "unprognostic (1.75e-1)" KLF16 "BTEB4, DRRF, NSLP2" ENSG00000129911 "KLF transcription factor 16" Q9BXK1 19 1852399-1863579 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 43.4" "Cell type enhanced" "Detected in many" "Early spermatids: 52.3;Late spermatids: 53.0;Retinal bipolar cells: 43.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052481 Approved Supported Nucleoplasm NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 18 Nucleoplasm "HPA052481: " "unprognostic (4.30e-1)" "unprognostic (3.26e-2)" "unprognostic (4.29e-2)" "unprognostic (4.43e-3)" "unprognostic (2.10e-1)" "unprognostic (1.77e-3)" "unprognostic (1.52e-1)" "unprognostic (4.39e-3)" "unprognostic (2.15e-1)" "unprognostic (5.83e-2)" "unprognostic (6.35e-3)" "unprognostic (4.80e-2)" "unprognostic (3.39e-2)" "unprognostic (2.25e-3)" "unprognostic (2.39e-3)" "unprognostic (2.29e-2)" "unprognostic (6.25e-3)" "unprognostic (1.60e-1)" "unprognostic (1.61e-2)" "potential prognostic unfavorable (3.32e-4)" "unprognostic (2.09e-1)" "unprognostic (4.27e-2)" "unprognostic (2.09e-1)" "unprognostic (5.86e-2)" "unprognostic (6.14e-2)" "unprognostic (1.78e-2)" "unprognostic (3.90e-2)" "unprognostic (3.19e-2)" "unprognostic (5.92e-2)" "unprognostic (1.80e-1)" "unprognostic (2.09e-2)" KLF17 "FLJ40160, Zfp393, ZNF393" ENSG00000171872 "KLF transcription factor 17" Q5JT82 1 44118821-44135140 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "testis: 8.0" "Cell type enriched" "Detected in some" 4 "Early spermatids: 249.4" "Cell type enriched" "Detected in single" 5 "oligodendrocyte precursor cell: 1.3" "Cancer enriched" "Detected in single" 20 "Testicular Germ Cell Tumor (TCGA): 7.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "Adrenocortical cancer: 3.6" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA024629 Enhanced NA NA "Cluster 67: Testis - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 1 "HPA024629: " "unprognostic (1.99e-1)" "unprognostic (9.55e-2)" "unprognostic (7.60e-2)" KLF18 ENSG00000283039 "KLF transcription factor 18" A0A0U1RQI7 1 44137821-44141631 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA KLF2 LKLF ENSG00000127528 "KLF transcription factor 2" Q9Y5W3 19 16324826-16328685 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "B-cells: 765.7;Foveolar cells: 532.3;Innate lymphoid cells: 408.3;Lymphatic endothelial cells: 534.2;Monocyte progenitors: 384.4;Myosatellite cells: 395.2;Neutrophils: 1079.9;NK-cells: 428.9;Plasma cells: 683.2;Smooth muscle cells: 627.9;Vascular endothelial cells: 636.1;Vascular smooth muscle cells: 652.5" "Cell type enhanced" "Detected in many" "endothelial cell: 567.9;leukocyte: 174.5;vascular associated smooth muscle cell: 227.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Myeloma: 61.1" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055964, HPA076411" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 47: Endothelial cells - Vasculature" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 11 Nucleoplasm Cytosol "HPA055964: , HPA076411: " "unprognostic (2.15e-1)" "unprognostic (1.02e-2)" "unprognostic (2.81e-3)" "unprognostic (1.17e-1)" "unprognostic (7.76e-3)" "unprognostic (4.68e-2)" "unprognostic (1.79e-1)" "unprognostic (1.43e-1)" "potential prognostic favorable (5.36e-4)" "unprognostic (6.64e-2)" "validated prognostic favorable (4.14e-8)" "validated prognostic favorable (1.25e-4)" "unprognostic (8.97e-3)" "validated prognostic favorable (1.23e-6)" "validated prognostic favorable (5.01e-5)" "unprognostic (2.57e-3)" "unprognostic (4.28e-3)" "unprognostic (2.59e-2)" "unprognostic (2.16e-1)" "unprognostic (4.19e-2)" "unprognostic (2.90e-3)" "unprognostic (3.68e-1)" "unprognostic (3.76e-3)" "unprognostic (2.25e-1)" "unprognostic (3.32e-1)" "unprognostic (5.82e-3)" "unprognostic (8.09e-2)" "unprognostic (1.36e-1)" "unprognostic (2.27e-2)" "unprognostic (1.41e-1)" "unprognostic (6.32e-2)" KLF3 BKLF ENSG00000109787 "KLF transcription factor 3" P57682 4 38664197-38701517 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 977.0;Esophageal suprabasal cells: 415.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049512, HPA065054" Supported Enhanced Nucleoplasm NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 47: Leukemia - Hemostasis" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 81 Nucleoplasm "HPA049512: , HPA065054: " "unprognostic (9.18e-3)" "unprognostic (2.54e-1)" "unprognostic (8.90e-2)" "unprognostic (1.55e-1)" "unprognostic (2.73e-3)" "unprognostic (2.83e-1)" "unprognostic (2.75e-1)" "unprognostic (1.84e-2)" "unprognostic (5.56e-2)" "unprognostic (1.28e-2)" "validated prognostic favorable (1.79e-5)" "validated prognostic favorable (2.98e-4)" "unprognostic (1.96e-1)" "unprognostic (2.32e-2)" "unprognostic (1.13e-1)" "unprognostic (1.65e-2)" "unprognostic (4.47e-2)" "unprognostic (1.37e-1)" "unprognostic (8.50e-2)" "unprognostic (6.95e-2)" "unprognostic (7.17e-2)" "potential prognostic unfavorable (1.52e-5)" "unprognostic (4.98e-1)" "unprognostic (1.92e-1)" "unprognostic (1.01e-1)" "unprognostic (9.34e-2)" "unprognostic (1.81e-1)" "unprognostic (1.88e-1)" "unprognostic (2.47e-1)" "unprognostic (4.51e-2)" "unprognostic (8.01e-2)" KLF4 "EZF, GKLF" ENSG00000136826 "KLF transcription factor 4" O43474 9 107484852-107490482 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 185.8" "Cell type enhanced" "Detected in many" "Breast secretory cells: 465.6;Colonocytes: 645.1;Esophageal apical cells: 600.4;Goblet cells: 916.9;Ocular epithelial cells: 494.6;Suprabasal keratinocytes: 583.4" "Cell type enhanced" "Detected in some" "endothelial cell: 101.2;fibroblast: 36.6;vascular associated smooth muscle cell: 47.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.0;non-classical monocyte: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells, Liver - Vascular endothelial cells, Spleen - Endothelial cells, Stomach - Gastric mucous cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002926 Enhanced Approved Nucleoplasm,Microtubules,Cytosol NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 58: Skin - Keratinization" "Cluster 47: Endothelial cells - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 70: Intestinal goblet cells - Mucin production" 31 Nucleoplasm "Microtubules, Cytosol" "HPA002926: " "unprognostic (2.55e-2)" "unprognostic (1.72e-1)" "unprognostic (2.56e-2)" "unprognostic (1.99e-2)" "unprognostic (5.12e-3)" "unprognostic (1.06e-1)" "unprognostic (3.31e-1)" "unprognostic (3.77e-3)" "unprognostic (2.90e-3)" "unprognostic (8.80e-2)" "validated prognostic favorable (2.11e-5)" "validated prognostic favorable (1.13e-4)" "unprognostic (1.07e-2)" "unprognostic (4.46e-2)" "unprognostic (4.96e-2)" "unprognostic (3.16e-3)" "unprognostic (5.82e-2)" "unprognostic (1.59e-1)" "unprognostic (2.54e-1)" "unprognostic (8.49e-2)" "unprognostic (4.23e-2)" "unprognostic (1.42e-3)" "unprognostic (2.50e-1)" "unprognostic (1.36e-1)" "unprognostic (1.42e-1)" "unprognostic (1.35e-1)" "unprognostic (3.17e-1)" "unprognostic (2.87e-1)" "unprognostic (2.26e-1)" "unprognostic (1.20e-1)" "unprognostic (2.99e-2)" KLF5 "BTEB2, CKLF, IKLF" ENSG00000102554 "KLF transcription factor 5" Q13887 13 73054976-73077541 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 226.7;skin 1: 221.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 804.1;Colonocytes: 990.8;Endometrial glandular cells: 1230.0;Endometrial luminal cells: 900.8;Epididymal basal cells: 1194.1;Esophageal apical cells: 1306.4;Esophageal suprabasal cells: 909.1;Ocular epithelial cells: 1697.8;Suprabasal keratinocytes: 1076.7;Urothelial cells: 1022.2" "Cell type enhanced" "Detected in many" "fibroblast: 61.3;medium spiny neuron: 50.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 20 "basophil: 24.0" "Lineage enriched" "Detected in single" 140 "granulocytes: 24.0" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Urothelial cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 30.7" HPA040398 Approved Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 33: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 38 Nucleoplasm "Golgi apparatus, Vesicles" "HPA040398: " "unprognostic (1.29e-2)" "unprognostic (1.14e-2)" "unprognostic (1.51e-1)" "unprognostic (1.26e-1)" "unprognostic (1.44e-2)" "unprognostic (2.81e-2)" "unprognostic (2.64e-2)" "unprognostic (3.55e-2)" "unprognostic (2.73e-1)" "unprognostic (1.29e-1)" "potential prognostic favorable (9.49e-5)" "unprognostic (3.95e-2)" "unprognostic (3.86e-2)" "unprognostic (1.17e-1)" "unprognostic (5.85e-2)" "unprognostic (1.19e-3)" "unprognostic (5.58e-2)" "unprognostic (3.23e-2)" "unprognostic (5.10e-3)" "unprognostic (3.75e-2)" "unprognostic (2.26e-2)" "potential prognostic unfavorable (6.40e-4)" "unprognostic (9.32e-2)" "unprognostic (5.10e-2)" "unprognostic (2.51e-2)" "unprognostic (1.58e-1)" "unprognostic (3.55e-1)" "unprognostic (4.38e-3)" "unprognostic (1.59e-1)" "unprognostic (1.66e-1)" "unprognostic (2.64e-1)" KLF6 "BCD1, COPEB, CPBP, GBF, PAC1, ST12, Zf9" ENSG00000067082 "KLF transcription factor 6" Q99612 10 3775996-3785281 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 412.7" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 2246.3;Epididymal basal cells: 2752.0;Epididymal efferent duct absorptive cells: 2778.8" "Cell type enhanced" "Detected in all" "endothelial cell: 296.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013529, HPA069585" Supported Supported "Nucleoplasm,Nucleoli,Nucleoli fibrillar center,Vesicles,Cytosol" No No "Cluster 41: Basophils - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 12: Non-specific - Vasculature" "Cluster 52: Non-specific - Mitochondria" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 9 Nucleoplasm "Nucleoli, Nucleoli fibrillar center, Vesicles, Cytosol" "CAB013529: , HPA069585: " "unprognostic (7.45e-2)" "unprognostic (1.58e-1)" "unprognostic (3.47e-3)" "potential prognostic unfavorable (3.01e-4)" "unprognostic (3.54e-3)" "unprognostic (2.30e-1)" "unprognostic (1.18e-1)" "unprognostic (2.98e-2)" "unprognostic (1.62e-1)" "unprognostic (3.42e-2)" "potential prognostic favorable (2.14e-7)" "unprognostic (1.77e-3)" "unprognostic (3.83e-2)" "unprognostic (1.40e-1)" "unprognostic (1.30e-1)" "unprognostic (2.83e-1)" "unprognostic (5.03e-2)" "unprognostic (1.70e-3)" "unprognostic (2.97e-2)" "unprognostic (7.75e-3)" "unprognostic (3.92e-1)" "unprognostic (1.03e-2)" "unprognostic (4.13e-3)" "unprognostic (3.76e-2)" "unprognostic (1.72e-2)" "potential prognostic favorable (8.17e-4)" "unprognostic (1.51e-1)" "unprognostic (4.97e-3)" "unprognostic (7.44e-2)" "unprognostic (6.79e-2)" "unprognostic (5.97e-2)" KLF7 UKLF ENSG00000118263 "KLF transcription factor 7" O75840 2 207074137-207173856 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophil progenitors: 565.2;Neutrophils: 979.7;Podocytes: 697.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Prostate - Smooth muscle cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003423, HPA030490" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 1 Nucleoplasm Cytosol "HPA003423: , HPA030490: " "unprognostic (4.08e-1)" "unprognostic (1.70e-2)" "unprognostic (1.87e-1)" "unprognostic (1.37e-3)" "unprognostic (3.96e-3)" "unprognostic (7.04e-2)" "unprognostic (1.97e-1)" "unprognostic (4.21e-1)" "unprognostic (2.04e-2)" "unprognostic (6.62e-3)" "potential prognostic favorable (5.62e-7)" "unprognostic (2.56e-3)" "unprognostic (4.25e-2)" "unprognostic (4.29e-2)" "unprognostic (3.27e-1)" "unprognostic (4.40e-2)" "unprognostic (2.59e-2)" "unprognostic (1.16e-2)" "unprognostic (9.57e-2)" "unprognostic (3.67e-2)" "unprognostic (6.09e-2)" "unprognostic (2.29e-2)" "unprognostic (1.67e-3)" "unprognostic (1.45e-1)" "unprognostic (4.16e-2)" "unprognostic (4.62e-3)" "unprognostic (3.98e-1)" "unprognostic (2.73e-3)" "unprognostic (4.03e-2)" "unprognostic (8.35e-3)" "unprognostic (1.43e-1)" KLF8 "BKLF3, DXS741, ZNF741" ENSG00000102349 "KLF transcription factor 8" O95600 X 56232356-56291531 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 58.4;Esophageal apical cells: 123.9;Esophageal suprabasal cells: 72.6;Leydig cells: 78.4;Peritubular myoid cells: 48.6;Sertoli cells: 52.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071740 Supported Nucleoplasm NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 58: Skin - Keratinization" "Cluster 31: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 10 Nucleoplasm "HPA071740: " "unprognostic (9.98e-2)" "unprognostic (1.11e-1)" "unprognostic (3.18e-1)" "unprognostic (1.24e-1)" "unprognostic (2.32e-2)" "unprognostic (1.04e-1)" "unprognostic (7.30e-3)" "unprognostic (6.07e-3)" "unprognostic (6.02e-3)" "unprognostic (6.71e-2)" "unprognostic (2.62e-2)" "unprognostic (3.92e-1)" "unprognostic (1.96e-2)" "unprognostic (1.42e-1)" "unprognostic (1.77e-1)" "unprognostic (1.04e-1)" "unprognostic (4.05e-1)" "unprognostic (8.51e-2)" "unprognostic (1.43e-1)" "unprognostic (2.38e-1)" "unprognostic (1.26e-1)" "unprognostic (1.63e-1)" KLF9 BTEB1 ENSG00000119138 "KLF transcription factor 9" Q13886 9 70384604-70414657 "Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 360.2;Pericytes: 367.2;Platelets: 422.6;Schwann cells: 579.9;Thymic myoid cells: 478.6;Vascular smooth muscle cells: 340.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "skin cancer: 34.1" "Adrenal gland - Fibroblasts, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029308 Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 37: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 103: Non-specific - Basic cellular processes" 2 Nucleoplasm "Plasma membrane, Cytosol" "HPA029308: " "unprognostic (4.34e-3)" "unprognostic (9.40e-2)" "unprognostic (1.17e-1)" "unprognostic (2.32e-1)" "unprognostic (3.42e-1)" "unprognostic (3.10e-3)" "unprognostic (1.70e-1)" "unprognostic (5.95e-3)" "unprognostic (2.00e-1)" "unprognostic (9.79e-2)" "validated prognostic favorable (1.34e-9)" "validated prognostic favorable (1.24e-4)" "unprognostic (4.62e-3)" "unprognostic (5.40e-3)" "potential prognostic favorable (2.20e-4)" "unprognostic (1.47e-1)" "unprognostic (1.37e-1)" "unprognostic (2.26e-2)" "unprognostic (2.21e-2)" "unprognostic (6.79e-3)" "unprognostic (1.59e-1)" "unprognostic (1.03e-1)" "unprognostic (2.13e-1)" "unprognostic (5.22e-2)" "unprognostic (2.79e-2)" "unprognostic (9.82e-2)" "unprognostic (4.54e-1)" "potential prognostic unfavorable (9.99e-5)" "unprognostic (1.95e-1)" "unprognostic (2.10e-2)" "unprognostic (2.11e-1)" KLHDC1 MST025 ENSG00000197776 "Kelch domain containing 1" Q8N7A1 14 49693105-49753150 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 205.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020461 Approved Supported Cytosol No No "Cluster 24: Non-specific - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 7: Non-specific - Transcription" Cytosol "HPA020461: " "unprognostic (3.94e-1)" "unprognostic (1.07e-1)" "unprognostic (2.49e-1)" "unprognostic (2.98e-1)" "unprognostic (1.56e-1)" "unprognostic (1.46e-1)" "unprognostic (3.78e-3)" "potential prognostic favorable (1.37e-4)" "unprognostic (1.10e-2)" "unprognostic (1.42e-3)" "unprognostic (8.65e-3)" "unprognostic (6.21e-2)" "unprognostic (4.43e-2)" "unprognostic (1.80e-1)" "potential prognostic favorable (6.32e-4)" "unprognostic (1.41e-1)" "unprognostic (1.93e-1)" "unprognostic (3.58e-2)" "unprognostic (5.92e-2)" "unprognostic (1.04e-1)" "unprognostic (4.96e-2)" KLHDC10 "KIAA0265, slim" ENSG00000128607 "Kelch domain containing 10" Q6PID8 7 130070534-130135705 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Spleen - Endothelial cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020119 Approved Approved Nucleoplasm NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 39: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 3 Nucleoplasm "HPA020119: " "unprognostic (1.14e-2)" "unprognostic (5.14e-2)" "unprognostic (1.88e-1)" "unprognostic (1.24e-2)" "unprognostic (1.13e-1)" "unprognostic (1.49e-1)" "unprognostic (4.36e-2)" "unprognostic (2.30e-2)" "unprognostic (4.58e-2)" "potential prognostic unfavorable (1.75e-4)" "potential prognostic favorable (1.09e-5)" "unprognostic (1.56e-2)" "unprognostic (2.39e-2)" "unprognostic (2.70e-1)" "unprognostic (1.96e-1)" "unprognostic (2.55e-1)" "unprognostic (4.52e-2)" "unprognostic (2.34e-1)" "unprognostic (6.52e-2)" "unprognostic (1.18e-1)" "unprognostic (1.39e-1)" "unprognostic (2.36e-1)" "unprognostic (2.78e-2)" "unprognostic (1.13e-1)" "unprognostic (1.08e-1)" "unprognostic (6.43e-2)" "unprognostic (1.42e-1)" "unprognostic (3.05e-1)" "unprognostic (1.97e-1)" "unprognostic (2.66e-2)" "unprognostic (2.72e-2)" KLHDC2 "HCLP-1, LCP" ENSG00000165516 "Kelch domain containing 2" Q9Y2U9 14 49768130-49786385 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 292.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Liver - Hepatocytes, Spleen - Endothelial cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000628 Approved Supported "Nucleoplasm,Nuclear membrane,Nuclear bodies" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 76: Non-specific - Metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 29 "Nucleoplasm, Nuclear membrane" "Nuclear bodies" "HPA000628: " "unprognostic (1.15e-2)" "unprognostic (1.42e-1)" "unprognostic (2.42e-2)" "unprognostic (7.29e-2)" "unprognostic (9.20e-2)" "unprognostic (1.74e-1)" "unprognostic (1.63e-2)" "unprognostic (1.08e-2)" "unprognostic (1.45e-1)" "unprognostic (1.28e-2)" "validated prognostic favorable (9.20e-11)" "validated prognostic favorable (3.84e-4)" "unprognostic (1.67e-2)" "unprognostic (2.57e-1)" "unprognostic (2.05e-2)" "unprognostic (1.48e-2)" "unprognostic (2.94e-2)" "unprognostic (2.02e-1)" "unprognostic (3.78e-1)" "unprognostic (1.39e-1)" "unprognostic (2.98e-1)" "unprognostic (2.77e-1)" "unprognostic (4.15e-1)" "unprognostic (1.40e-1)" "unprognostic (1.37e-1)" "unprognostic (2.62e-1)" "unprognostic (1.00e-1)" "unprognostic (2.97e-3)" "unprognostic (1.80e-1)" "unprognostic (8.73e-2)" "unprognostic (1.18e-1)" KLHDC3 "dJ20C7.3, hPeas, PEAS" ENSG00000124702 "Kelch domain containing 3" Q9BQ90 6 43014103-43021298 "Predicted intracellular proteins" "Meiosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 370.7" "Cell type enriched" "Detected in many" 4 "Late spermatids: 2541.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030131, HPA030132, HPA030133, HPA030134" Uncertain Enhanced Nucleoplasm NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 28 Nucleoplasm "HPA030131: , HPA030132: , HPA030133: , HPA030134: " "unprognostic (2.01e-1)" "unprognostic (1.82e-1)" "unprognostic (5.53e-3)" "unprognostic (3.96e-2)" "unprognostic (8.82e-2)" "unprognostic (2.49e-1)" "unprognostic (5.59e-2)" "potential prognostic favorable (4.92e-5)" "unprognostic (2.80e-1)" "unprognostic (8.24e-2)" "potential prognostic favorable (8.20e-4)" "unprognostic (1.83e-2)" "unprognostic (5.59e-2)" "validated prognostic unfavorable (4.14e-5)" "validated prognostic unfavorable (6.64e-5)" "unprognostic (2.96e-1)" "unprognostic (1.34e-1)" "unprognostic (2.30e-3)" "unprognostic (1.37e-1)" "unprognostic (2.91e-2)" "unprognostic (5.18e-2)" "unprognostic (4.24e-3)" "unprognostic (3.35e-2)" "unprognostic (5.45e-2)" "unprognostic (4.55e-2)" "unprognostic (8.09e-2)" "unprognostic (4.21e-3)" "unprognostic (7.05e-3)" "unprognostic (5.61e-2)" "unprognostic (3.05e-1)" "unprognostic (3.30e-2)" KLHDC4 DKFZp434G0522 ENSG00000104731 "Kelch domain containing 4" Q8TBB5 16 87696485-87765992 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 130.0;pDCs: 113.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041665 Approved Approved Nucleoli,Kinetochore Yes No "Cluster 3: Non-specific - Nuclear processes" "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 11 Nucleoli Kinetochore "HPA041665: " "unprognostic (2.84e-1)" "unprognostic (3.37e-1)" "unprognostic (3.70e-2)" "unprognostic (2.02e-1)" "unprognostic (1.04e-1)" "unprognostic (4.80e-2)" "unprognostic (1.20e-1)" "potential prognostic favorable (3.26e-4)" "unprognostic (5.06e-2)" "unprognostic (1.80e-2)" "unprognostic (7.43e-3)" "unprognostic (3.53e-1)" "unprognostic (1.02e-3)" "unprognostic (4.28e-2)" "unprognostic (2.17e-1)" "unprognostic (2.24e-1)" "unprognostic (5.99e-2)" "unprognostic (1.75e-2)" "unprognostic (9.59e-2)" "unprognostic (3.30e-1)" "unprognostic (1.51e-1)" "unprognostic (1.02e-2)" "unprognostic (1.42e-2)" "unprognostic (1.82e-3)" "unprognostic (6.81e-2)" "unprognostic (2.55e-1)" "unprognostic (9.93e-2)" "unprognostic (9.06e-2)" "unprognostic (4.11e-2)" "unprognostic (3.15e-2)" "unprognostic (3.91e-2)" KLHDC7A FLJ38753 ENSG00000179023 "Kelch domain containing 7A" Q5VTJ3 1 18480930-18485974 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 18.2" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 10.5;Conjunctival goblet cells: 7.8;Epididymal efferent duct absorptive cells: 7.2;Epididymal efferent duct ciliated cells: 6.7;Esophageal apical cells: 6.5;Foveolar cells: 15.8;Hepatocytes: 8.5;Loop of henle epithelial cells: 7.1;Papillary tip epithelial cells: 7.3;Proximal tubule cells: 6.8;Renal collecting duct principal cells: 7.2;Respiratory ciliated cells: 9.7;Respiratory secretory cells: 6.3;Salivary duct cells: 8.5" "Cell type enriched" "Detected in single" 13 "choroid plexus epithelial cell: 9.2" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 21.5" "Region enriched" "Detected in some" 12 "choroid plexus: 18.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 9.3" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" HPA056616 Uncertain Approved "Nuclear speckles" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 68: Foveolar cells - Mucosal defense" "Nuclear speckles" "HPA056616: " "unprognostic (9.97e-3)" "unprognostic (2.35e-1)" "unprognostic (1.96e-1)" "unprognostic (1.01e-2)" "unprognostic (1.99e-1)" "validated prognostic favorable (4.37e-8)" "validated prognostic favorable (1.43e-4)" "potential prognostic favorable (1.93e-5)" "unprognostic (6.79e-3)" "unprognostic (2.73e-1)" "potential prognostic favorable (3.20e-5)" "unprognostic (3.98e-2)" "unprognostic (5.05e-2)" "unprognostic (1.36e-1)" "unprognostic (1.48e-2)" "unprognostic (1.96e-1)" "unprognostic (1.73e-1)" KLHDC7B MGC16635 ENSG00000130487 "Kelch domain containing 7B" Q96G42 22 50545899-50551023 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 4.8;parathyroid gland: 12.8" "Cell type enhanced" "Detected in some" "Breast hormone-responsive cells: 5.0;Conjunctival goblet cells: 7.8;Endometrial secretory cells: 8.1;Kupffer cells: 5.1;Mast cells: 7.8;Monocyte progenitors: 3.0;NK-cells: 2.8;Papillary tip epithelial cells: 2.7;pDCs: 3.9;Plasma cells: 4.6;Renal connecting tubule cells: 6.0;T-cells: 3.1;Thymic myoid cells: 2.7" "Cell type enriched" "Detected in single" 6 "leukocyte: 2.3" "Group enriched" "Detected in many" 4 "Bladder Urothelial Carcinoma (TCGA): 65.8;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 71.0" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Bladder cancer: 5.5" "Pituitary gland - Thyrotropes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA000518, HPA076540" Uncertain Approved "Plasma membrane" NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 58: Mast cells - Allergic inflammatory responses" 15 "Plasma membrane" "HPA000518: , HPA076540: " "unprognostic (1.92e-2)" "potential prognostic favorable (8.65e-4)" "unprognostic (3.77e-2)" "unprognostic (3.97e-2)" "unprognostic (1.60e-1)" "unprognostic (3.23e-3)" "unprognostic (7.19e-2)" "potential prognostic unfavorable (1.19e-4)" "unprognostic (9.19e-2)" "unprognostic (6.70e-2)" "unprognostic (2.54e-1)" "unprognostic (4.28e-2)" "unprognostic (9.17e-2)" "unprognostic (6.20e-2)" "unprognostic (1.42e-1)" "unprognostic (1.58e-2)" "unprognostic (2.05e-1)" "unprognostic (1.74e-1)" "unprognostic (4.22e-3)" "potential prognostic unfavorable (4.14e-4)" "unprognostic (6.29e-3)" "unprognostic (1.04e-2)" "unprognostic (1.58e-1)" "unprognostic (1.48e-2)" "unprognostic (2.63e-1)" "unprognostic (3.33e-1)" KLHDC8A FLJ10748 ENSG00000162873 "Kelch domain containing 8A" Q8IYD2 1 205336061-205357090 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "ovary: 277.5" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 33.0;Bergmann glia: 118.0;Ependymal cells: 69.2;Gonadotrophs: 50.3;Granulosa cells: 73.8;Müller glia: 49.3;Ovarian stromal cells: 199.7;Peritubular myoid cells: 34.5;Pituicytes/FSCs: 50.6;Retinal bipolar cells: 95.5" "Cell type enhanced" "Detected in many" "Bergmann glia: 117.1;ependymal cell: 86.4" "Group enriched" "Detected in many" 6 "Glioblastoma Multiforme (TCGA): 93.7;Thyroid Carcinoma (TCGA): 29.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 25.5;thyroid cancer: 10.1" "Adrenal gland - Adrenal cortex cells, Colon - Enteric glia cells, Pancreas - Beta cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Stomach - Parietal cells, Testis - Peritubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA079383 Approved Nucleoplasm,Cytosol NA NA "Cluster 75: Ovary - Mixed function" "Cluster 44: Non-specific - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 94: Gonadal somatic cells - Mixed function" 12 Nucleoplasm Cytosol "HPA079383: " "unprognostic (1.75e-3)" "unprognostic (8.49e-2)" "unprognostic (1.17e-1)" "unprognostic (4.79e-2)" "unprognostic (7.89e-2)" "unprognostic (2.85e-2)" "unprognostic (1.74e-1)" "unprognostic (8.93e-2)" "unprognostic (6.69e-2)" "unprognostic (4.24e-2)" "unprognostic (9.69e-3)" "unprognostic (1.97e-1)" "unprognostic (1.69e-2)" "unprognostic (1.19e-2)" "unprognostic (7.02e-3)" "unprognostic (1.60e-1)" "unprognostic (3.28e-2)" "unprognostic (3.20e-3)" "unprognostic (5.61e-2)" KLHDC8B MGC35097 ENSG00000185909 "Kelch domain containing 8B" Q8IXV7 3 49171598-49176486 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 123.7" "Cell type enriched" "Detected in many" 4 "Platelets: 388.1" "Cell type enhanced" "Detected in many" "pericyte: 54.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 28.8" "Group enriched" "Detected in many" 10 "granulocytes: 28.8;monocytes: 8.4" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008463, HPA014467" Approved Enhanced Cytosol NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 47: Leukemia - Hemostasis" "Cluster 47: Platelets - Hemostasis" 3 Cytosol "HPA008463: , HPA014467: " "unprognostic (2.34e-1)" "unprognostic (1.03e-1)" "unprognostic (2.39e-1)" "unprognostic (1.66e-1)" "unprognostic (6.49e-3)" "unprognostic (2.84e-1)" "unprognostic (7.03e-2)" "unprognostic (2.40e-2)" "unprognostic (2.59e-2)" "unprognostic (1.17e-1)" "potential prognostic favorable (1.36e-7)" "unprognostic (6.44e-3)" "potential prognostic favorable (6.76e-4)" "potential prognostic unfavorable (9.41e-4)" "unprognostic (5.59e-2)" "unprognostic (1.56e-3)" "unprognostic (2.82e-1)" "unprognostic (2.15e-2)" "unprognostic (1.35e-1)" "unprognostic (7.96e-2)" "unprognostic (1.42e-1)" "unprognostic (2.32e-2)" "unprognostic (2.58e-1)" "unprognostic (3.15e-2)" "unprognostic (3.00e-2)" "unprognostic (1.67e-1)" "unprognostic (3.60e-2)" "unprognostic (1.64e-2)" "unprognostic (1.73e-1)" "unprognostic (2.48e-2)" "unprognostic (6.51e-2)" KLHDC9 KARCA1 ENSG00000162755 "Kelch domain containing 9" Q8NEP7 1 161098361-161100346 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 24.6" "Group enriched" "Detected in many" 4 "Early spermatids: 381.9;Late primary spermatocytes: 473.0;Late spermatids: 589.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043197 Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes NA "Cluster 79: Testis - Spermatogenesis" "Cluster 24: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 2 "Nucleoplasm, Nucleoli, Nucleoli rim, Mitotic chromosome" "HPA043197: " "unprognostic (2.24e-1)" "unprognostic (1.44e-1)" "unprognostic (1.52e-2)" "potential prognostic unfavorable (5.75e-4)" "unprognostic (1.95e-2)" "unprognostic (1.09e-2)" "unprognostic (9.28e-2)" "unprognostic (4.70e-2)" "potential prognostic favorable (3.71e-4)" "unprognostic (8.04e-3)" "unprognostic (4.91e-1)" "unprognostic (2.53e-2)" "unprognostic (1.32e-1)" "unprognostic (2.75e-3)" "unprognostic (7.24e-2)" KLHL1 "FLJ30047, KIAA1490, MRP2" ENSG00000150361 "Kelch like family member 1" Q9NR64 13 69700594-70108493 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "brain: 12.0" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 105.6;Brain inhibitory neurons: 72.5;Corticotrophs: 511.1;Oligodendrocyte progenitor cells: 360.2;Other brain neurons: 263.1;Retinal amacrine cells: 191.1;Retinal ganglion cells: 158.4;Retinal horizontal cells: 56.1" "Cell type enhanced" "Detected in all" "lower rhombic lip: 368.7;oligodendrocyte precursor cell: 448.6;splatter: 326.0" "Cancer enriched" "Detected in single" 7 "Breast Invasive Carcinoma (TCGA): 1.2" "Region enhanced" "Detected in many" "midbrain: 69.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "prostate cancer: 3.0" "Colon - Colon enteroendocrine cells, Pituitary gland - Corticotropes, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA021196 Uncertain NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 109: Neurons - Neuronal signaling" 6 "HPA021196: " "unprognostic (1.53e-1)" "unprognostic (4.50e-1)" KLHL10 FLJ32662 ENSG00000161594 "Kelch like family member 10" Q6JEL2 17 41835685-41848384 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Spermatogenesis, Ubl conjugation pathway" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 37 "testis: 55.3" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 66.7;Early spermatids: 358.8;Late primary spermatocytes: 223.7;Late spermatids: 900.6" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA067538 Enhanced Approved "Mid piece" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 15: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 8 "Mid piece" "HPA067538: " KLHL11 FLJ10572 ENSG00000178502 "Kelch like family member 11" Q9NVR0 17 41848518-41865423 "Essential proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 158.2;Late spermatids: 58.6;Retinal horizontal cells: 34.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Kidney - Macrophages, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023021, HPA052403, HPA054269" Uncertain Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 40: Non-specific - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 5 Nucleoplasm "Nuclear membrane" "HPA023021: , HPA052403: , HPA054269: " "unprognostic (1.46e-1)" "unprognostic (1.41e-2)" "unprognostic (1.67e-1)" "unprognostic (6.06e-2)" "unprognostic (7.46e-2)" "unprognostic (6.45e-3)" "unprognostic (2.68e-1)" "unprognostic (5.82e-3)" "unprognostic (6.87e-2)" "potential prognostic unfavorable (3.46e-4)" "unprognostic (8.45e-3)" "unprognostic (2.15e-1)" "unprognostic (1.42e-1)" "unprognostic (1.95e-1)" "unprognostic (1.42e-1)" "unprognostic (2.63e-1)" "unprognostic (2.01e-1)" "potential prognostic favorable (1.57e-4)" "unprognostic (1.26e-2)" "unprognostic (4.99e-3)" "unprognostic (1.87e-1)" "unprognostic (1.27e-1)" "unprognostic (6.97e-3)" "unprognostic (1.67e-2)" "unprognostic (4.87e-2)" "unprognostic (1.84e-1)" "unprognostic (4.88e-2)" "unprognostic (2.49e-2)" "unprognostic (3.77e-1)" KLHL12 C3IP1 ENSG00000117153 "Kelch like family member 12" Q53G59 1 202891116-202928636 "Predicted intracellular proteins" "ER-Golgi transport, Transport, Ubl conjugation pathway, Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 146.5;Late primary spermatocytes: 103.8;Late spermatids: 118.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071324 Supported "Vesicles,Centriolar satellite" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 61: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 78 "Vesicles, Centriolar satellite" "HPA071324: " "unprognostic (1.62e-1)" "unprognostic (1.23e-2)" "unprognostic (3.11e-2)" "unprognostic (2.26e-2)" "unprognostic (1.86e-1)" "unprognostic (9.13e-2)" "unprognostic (2.25e-1)" "unprognostic (7.19e-2)" "unprognostic (1.49e-1)" "unprognostic (2.33e-2)" "potential prognostic favorable (5.48e-4)" "unprognostic (8.21e-2)" "unprognostic (2.03e-2)" "potential prognostic unfavorable (8.07e-4)" "unprognostic (6.22e-2)" "unprognostic (7.76e-2)" "unprognostic (3.34e-2)" "unprognostic (5.19e-2)" "unprognostic (1.03e-1)" "unprognostic (2.75e-1)" "unprognostic (4.69e-3)" "unprognostic (6.33e-2)" "unprognostic (1.85e-1)" "unprognostic (1.54e-1)" "unprognostic (6.26e-2)" "unprognostic (7.82e-2)" "unprognostic (1.58e-2)" "unprognostic (1.75e-2)" "unprognostic (3.17e-2)" "unprognostic (4.03e-2)" "unprognostic (1.82e-1)" KLHL13 "BKLHD2, FLJ10262, KIAA1309" ENSG00000003096 "Kelch like family member 13" Q9P2N7 X 117897813-118117340 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 29.2" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 212.7;Distal convoluted tubule cells: 518.6;Endometrial stromal cells: 171.4;Fibro-adipogenic progenitors: 179.8;Loop of henle epithelial cells: 411.6;Myosatellite cells: 181.3;Renal connecting tubule cells: 380.8;Thymocytes: 172.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 7.3;plasmacytoid DC: 4.1" "Group enriched" "Detected in many" 5 "dendritic cells: 4.1;granulocytes: 7.3" "Group enriched" "Detected in many" 5 "cervical cancer: 25.8;Neuroblastoma: 103.2" "Minor Salivary Gland - Fibroblasts, Testis - Spermatogonia, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046039, HPA059901" Approved Approved Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 75: Ovary - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 14 Cytosol "HPA046039: , HPA059901: " "unprognostic (1.49e-1)" "unprognostic (1.39e-1)" "unprognostic (5.40e-2)" "unprognostic (1.63e-1)" "unprognostic (8.95e-2)" "unprognostic (3.11e-2)" "unprognostic (4.58e-3)" "potential prognostic favorable (5.07e-4)" "unprognostic (5.67e-2)" "unprognostic (2.07e-1)" "potential prognostic favorable (3.81e-6)" "unprognostic (1.85e-1)" "unprognostic (5.49e-3)" "unprognostic (7.94e-2)" "potential prognostic unfavorable (5.32e-4)" "unprognostic (2.36e-2)" "unprognostic (1.45e-1)" "unprognostic (1.51e-2)" "unprognostic (5.99e-3)" "unprognostic (2.50e-1)" "unprognostic (3.15e-2)" "unprognostic (8.56e-2)" "unprognostic (8.99e-2)" "unprognostic (2.59e-1)" "unprognostic (9.35e-2)" "unprognostic (4.67e-2)" "unprognostic (3.44e-2)" "potential prognostic unfavorable (8.45e-4)" "unprognostic (6.15e-2)" "unprognostic (2.82e-2)" KLHL14 KIAA1384 ENSG00000197705 "Kelch like family member 14" Q9P2G3 18 32672673-32773023 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 8.2;seminal vesicle: 12.0;thyroid gland: 12.9" "Cell type enhanced" "Detected in many" "B-cells: 79.6;Distal convoluted tubule cells: 33.6;Endometrial ciliated cells: 49.0;Fallopian tube ciliated cells: 38.8;Loop of henle epithelial cells: 79.2;Lymphatic endothelial cells: 35.7;Müller glia: 58.7;Plasma cells: 57.5;Renal collecting duct principal cells: 74.7;Renal connecting tubule cells: 33.7" "Cell type enhanced" "Detected in many" "deep-layer near-projecting: 14.3;MGE interneuron: 14.4" "Group enriched" "Detected in many" 8 "Ovary Serous Cystadenocarcinoma (TCGA): 27.0;Thyroid Carcinoma (TCGA): 12.3;Uterine Corpus Endometrial Carcinoma (TCGA): 12.7" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 90 "memory B-cell: 10.6;naive B-cell: 7.3" "Lineage enriched" "Detected in single" 106 "B-cells: 10.6" "Cancer enhanced" "Detected in some" "lymphoma: 10.8;ovarian cancer: 10.6;Uterine cancer: 6.6" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 9 "hippocampal formation: 19.5;olfactory bulb: 10.9" HPA024777 Uncertain Supported "Actin filaments,Cytosol" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 33: Thyroid gland - Tissue development" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 55: Lymphoma - Immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 1 Cytosol "Actin filaments" "HPA024777: " "unprognostic (2.13e-2)" "unprognostic (1.98e-1)" "unprognostic (3.44e-1)" "unprognostic (8.48e-2)" "potential prognostic unfavorable (8.84e-4)" "unprognostic (3.86e-1)" "unprognostic (1.07e-1)" "unprognostic (1.40e-1)" "unprognostic (2.32e-3)" "unprognostic (1.47e-1)" KLHL15 KIAA1677 ENSG00000174010 "Kelch like family member 15" Q96M94 X 23983716-24027186 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 53.6" "Cell type enhanced" "Detected in many" "Monocyte progenitors: 130.4;Neutrophil progenitors: 139.6;Neutrophils: 164.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065730 Uncertain Approved Aggresome,Cytosol NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 36: Non-specific - mRNA processing" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 19 Cytosol Aggresome "HPA065730: " "unprognostic (4.43e-3)" "unprognostic (1.65e-1)" "unprognostic (5.51e-2)" "unprognostic (1.71e-1)" "unprognostic (1.06e-1)" "unprognostic (5.56e-3)" "unprognostic (4.35e-1)" "unprognostic (8.25e-2)" "unprognostic (3.40e-2)" "unprognostic (1.95e-1)" "potential prognostic favorable (3.09e-5)" "unprognostic (1.78e-2)" "unprognostic (1.02e-2)" "unprognostic (1.65e-1)" "unprognostic (9.78e-2)" "unprognostic (2.82e-1)" "unprognostic (1.53e-1)" "unprognostic (8.85e-3)" "unprognostic (5.70e-3)" "unprognostic (4.38e-2)" "unprognostic (8.96e-2)" "unprognostic (7.80e-2)" "unprognostic (4.12e-1)" "unprognostic (1.08e-1)" "unprognostic (8.71e-2)" "unprognostic (1.49e-2)" "unprognostic (5.07e-2)" "unprognostic (1.75e-1)" "unprognostic (1.81e-2)" "unprognostic (2.42e-1)" "unprognostic (8.37e-2)" KLHL17 ENSG00000187961 "Kelch like family member 17" Q6TDP4 1 960584-965719 "Predicted intracellular proteins" "Ubl conjugation pathway" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oocytes: 9.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031251 Approved Uncertain "Nucleoplasm,Nuclear bodies" NA NA "Cluster 64: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 20: Non-specific - Transcription regulation" 9 "Nuclear bodies" Nucleoplasm "HPA031251: " "unprognostic (7.72e-2)" "unprognostic (3.32e-2)" "unprognostic (8.71e-2)" "unprognostic (1.00e-3)" "unprognostic (7.82e-2)" "unprognostic (3.49e-2)" "unprognostic (1.76e-1)" "unprognostic (3.13e-2)" "unprognostic (4.68e-3)" "unprognostic (7.43e-2)" "potential prognostic unfavorable (3.77e-5)" "unprognostic (1.44e-1)" "unprognostic (9.49e-2)" "potential prognostic unfavorable (5.62e-5)" "unprognostic (3.83e-2)" "unprognostic (2.39e-2)" "unprognostic (2.68e-1)" "unprognostic (1.55e-1)" "unprognostic (5.82e-2)" "unprognostic (1.15e-1)" "unprognostic (1.21e-1)" "unprognostic (1.32e-2)" "unprognostic (3.11e-3)" "unprognostic (1.18e-2)" "unprognostic (1.07e-1)" "unprognostic (1.01e-3)" "unprognostic (8.56e-2)" "unprognostic (4.61e-2)" "unprognostic (1.16e-1)" "unprognostic (1.25e-1)" "unprognostic (4.66e-2)" KLHL18 "FLJ13703, KIAA0795" ENSG00000114648 "Kelch like family member 18" O94889 3 47282917-47346816 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 159.0;Retinal bipolar cells: 162.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035027, HPA035028" Approved Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 40: Non-specific - Mixed function" "Cluster 14: Neurons - Synaptic function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 7 Nucleoplasm "Nuclear bodies" "HPA035027: , HPA035028: " "unprognostic (7.47e-2)" "unprognostic (1.30e-1)" "unprognostic (1.79e-2)" "unprognostic (3.03e-1)" "unprognostic (6.07e-2)" "unprognostic (3.96e-1)" "unprognostic (1.37e-1)" "unprognostic (3.63e-3)" "unprognostic (1.09e-1)" "unprognostic (7.51e-3)" "unprognostic (6.45e-3)" "unprognostic (2.01e-2)" "unprognostic (1.74e-2)" "potential prognostic unfavorable (4.90e-4)" "unprognostic (1.71e-1)" "unprognostic (2.13e-1)" "unprognostic (2.79e-2)" "unprognostic (8.55e-3)" "unprognostic (1.41e-1)" "unprognostic (1.13e-1)" "unprognostic (2.19e-1)" "unprognostic (2.08e-1)" "unprognostic (1.35e-1)" "unprognostic (1.92e-2)" "unprognostic (2.54e-2)" "unprognostic (1.72e-1)" "unprognostic (2.59e-1)" "unprognostic (3.67e-2)" "unprognostic (1.38e-1)" "unprognostic (1.37e-1)" "unprognostic (1.42e-1)" KLHL2 MAV ENSG00000109466 "Kelch like family member 2" O95198 4 165207561-165323156 "Predicted intracellular proteins, Transporters" "Ubl conjugation pathway" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 48.1" "Cell type enriched" "Detected in many" 5 "Neutrophils: 2386.3" "Cell type enhanced" "Detected in all" "hippocampal dentate gyrus: 558.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 7.2" "Lineage enriched" "Detected in many" 6 "granulocytes: 7.2" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Kidney - Endothelial cells, Lung - Neutrophils_2, Minor Salivary Gland - Minor salivary glandular cells, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051637 Uncertain Nucleoplasm,Vesicles NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 36: Brain & Liver - Signaling" "Cluster 51: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 24: Neutrophils - Innate immunity signal integration" 40 Nucleoplasm Vesicles "HPA051637: " "unprognostic (2.25e-1)" "unprognostic (2.65e-1)" "unprognostic (1.95e-1)" "unprognostic (1.38e-1)" "unprognostic (6.99e-2)" "unprognostic (1.52e-1)" "unprognostic (2.82e-1)" "unprognostic (1.24e-1)" "unprognostic (2.77e-2)" "unprognostic (1.71e-2)" "validated prognostic favorable (6.32e-6)" "validated prognostic favorable (8.59e-4)" "unprognostic (5.98e-2)" "unprognostic (3.10e-1)" "unprognostic (2.78e-2)" "unprognostic (2.60e-2)" "unprognostic (1.23e-2)" "potential prognostic unfavorable (7.05e-4)" "unprognostic (4.82e-3)" "unprognostic (8.62e-2)" "unprognostic (4.39e-2)" "unprognostic (1.43e-1)" "unprognostic (4.40e-2)" "unprognostic (3.18e-1)" "unprognostic (2.15e-1)" "unprognostic (4.14e-2)" "unprognostic (1.77e-2)" "unprognostic (1.71e-1)" "unprognostic (1.80e-1)" "unprognostic (4.60e-2)" "unprognostic (5.01e-1)" KLHL20 "KHLHX, KLEIP" ENSG00000076321 "Kelch like family member 20" Q9Y2M5 1 173714941-173786692 "Predicted intracellular proteins" "Protein transport, Transport, Ubl conjugation pathway" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 213.8;Prostatic glandular cells: 223.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025034, HPA053704" Approved Supported "Golgi apparatus,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 115 "Golgi apparatus, Cytosol" "HPA025034: , HPA053704: " "unprognostic (6.72e-3)" "unprognostic (1.17e-2)" "unprognostic (5.28e-2)" "unprognostic (4.92e-3)" "unprognostic (1.47e-1)" "unprognostic (3.56e-2)" "unprognostic (1.23e-1)" "unprognostic (6.04e-3)" "unprognostic (4.73e-2)" "unprognostic (2.64e-1)" "potential prognostic favorable (2.80e-5)" "unprognostic (3.67e-3)" "unprognostic (2.37e-1)" "unprognostic (1.33e-1)" "unprognostic (1.70e-3)" "unprognostic (1.77e-1)" "unprognostic (4.25e-2)" "unprognostic (1.65e-1)" "unprognostic (2.36e-1)" "unprognostic (1.78e-1)" "unprognostic (8.73e-3)" "unprognostic (4.48e-2)" "unprognostic (4.25e-1)" "unprognostic (1.48e-1)" "unprognostic (7.06e-2)" "unprognostic (1.17e-1)" "unprognostic (1.48e-2)" "unprognostic (1.71e-1)" "unprognostic (2.36e-1)" "unprognostic (7.25e-2)" "unprognostic (1.24e-1)" KLHL21 KIAA0469 ENSG00000162413 "Kelch like family member 21" Q9UJP4 1 6590724-6614607 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 160.3" "Cell type enhanced" "Detected in many" "Breast secretory cells: 103.0;Epididymal basal cells: 114.3;Ocular epithelial cells: 131.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "eosinophil: 21.4;neutrophil: 62.8" "Lineage enriched" "Detected in all" 8 "granulocytes: 62.8" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051364, HPA059307" Uncertain Supported Centrosome NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 3: Choroid plexus - Cilium" "Cluster 37: Non-specific - mRNA processing" "Cluster 103: Non-specific - Basic cellular processes" 8 Centrosome "HPA051364: , HPA059307: " "unprognostic (3.24e-2)" "unprognostic (8.54e-2)" "unprognostic (1.11e-1)" "unprognostic (4.71e-1)" "unprognostic (1.12e-1)" "potential prognostic unfavorable (5.17e-6)" "unprognostic (3.74e-2)" "unprognostic (2.91e-1)" "unprognostic (2.38e-2)" "unprognostic (5.95e-2)" "potential prognostic favorable (7.04e-4)" "unprognostic (1.02e-3)" "unprognostic (5.31e-2)" "unprognostic (4.26e-2)" "unprognostic (6.51e-3)" "unprognostic (1.19e-2)" "unprognostic (5.16e-2)" "unprognostic (9.76e-2)" "unprognostic (1.22e-1)" "unprognostic (2.74e-2)" "unprognostic (1.84e-1)" "unprognostic (2.88e-1)" "unprognostic (1.89e-1)" "unprognostic (1.33e-2)" "unprognostic (1.65e-1)" "unprognostic (1.40e-2)" "unprognostic (1.51e-1)" "unprognostic (2.18e-1)" "unprognostic (3.83e-2)" "unprognostic (2.32e-2)" "unprognostic (2.11e-2)" KLHL22 "FLJ14360, KELCHL" ENSG00000099910 "Kelch like family member 22" Q53GT1 22 20441519-20495844 "Disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 106.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040766 Supported "Vesicles,Microtubules,Cytokinetic bridge,Mitotic spindle" Yes No "Cluster 33: Non-specific - ATP binding" "Cluster 65: Brain - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 66: Non-specific - Mitochondria" "Cluster 7: Non-specific - Transcription" 70 "Vesicles, Microtubules, Cytokinetic bridge, Mitotic spindle" "HPA040766: " "unprognostic (3.48e-3)" "unprognostic (3.13e-1)" "unprognostic (1.67e-1)" "unprognostic (3.18e-1)" "unprognostic (6.09e-2)" "unprognostic (1.31e-1)" "unprognostic (4.36e-1)" "unprognostic (1.08e-2)" "unprognostic (4.30e-3)" "unprognostic (7.45e-2)" "potential prognostic favorable (2.30e-6)" "unprognostic (6.57e-3)" "potential prognostic favorable (1.46e-5)" "unprognostic (4.14e-2)" "unprognostic (8.63e-2)" "unprognostic (2.86e-1)" "unprognostic (6.92e-2)" "unprognostic (1.29e-1)" "unprognostic (2.35e-2)" "unprognostic (2.10e-1)" "unprognostic (5.27e-2)" "potential prognostic favorable (1.58e-4)" "unprognostic (3.86e-2)" "unprognostic (2.19e-2)" "unprognostic (1.57e-1)" "unprognostic (3.19e-1)" "unprognostic (2.81e-1)" "unprognostic (1.08e-1)" "unprognostic (1.64e-1)" "unprognostic (4.11e-2)" "unprognostic (4.68e-2)" KLHL23 "FLJ37812, MGC22679, MGC2610" ENSG00000213160 "Kelch like family member 23" Q8NBE8 2 169694488-169776989 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 200.8;Retinal bipolar cells: 243.5;Vascular smooth muscle cells: 186.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 3.4" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047593 Approved "Nucleoplasm,Actin filaments" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 110: Mural cells - ECM organization" 5 "Actin filaments" Nucleoplasm "HPA047593: " "unprognostic (3.06e-2)" "unprognostic (2.61e-1)" "unprognostic (1.98e-1)" "unprognostic (2.31e-1)" "unprognostic (5.12e-2)" "unprognostic (2.61e-2)" "unprognostic (2.26e-2)" "unprognostic (3.65e-3)" "unprognostic (2.55e-2)" "unprognostic (1.30e-2)" "potential prognostic favorable (7.96e-5)" "unprognostic (1.18e-3)" "unprognostic (1.47e-3)" "unprognostic (2.19e-3)" "potential prognostic unfavorable (6.17e-4)" "unprognostic (8.42e-2)" "unprognostic (1.07e-1)" "unprognostic (1.33e-1)" "unprognostic (1.05e-3)" "unprognostic (7.16e-2)" "unprognostic (4.19e-1)" "unprognostic (2.80e-1)" "unprognostic (3.61e-3)" "unprognostic (1.95e-1)" "unprognostic (3.95e-3)" "unprognostic (1.19e-2)" "unprognostic (3.81e-2)" "unprognostic (2.09e-1)" "unprognostic (3.95e-1)" "unprognostic (1.66e-1)" "unprognostic (3.36e-1)" KLHL24 "DRE1, FLJ20059" ENSG00000114796 "Kelch like family member 24" Q6TFL4 3 183635610-183684519 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Cardiomyopathy, Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Myonuclei: 622.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056337 Uncertain NA NA "Cluster 32: Basophils - Transcription" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 16: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 5 "HPA056337: " "unprognostic (4.61e-2)" "unprognostic (1.96e-1)" "unprognostic (3.47e-1)" "unprognostic (1.31e-1)" "unprognostic (5.01e-2)" "unprognostic (1.38e-1)" "unprognostic (8.36e-2)" "unprognostic (1.44e-1)" "unprognostic (2.63e-1)" "unprognostic (2.04e-2)" "validated prognostic favorable (1.62e-5)" "validated prognostic favorable (4.70e-5)" "unprognostic (4.01e-1)" "unprognostic (2.36e-1)" "unprognostic (8.21e-2)" "unprognostic (1.15e-2)" "unprognostic (8.27e-2)" "unprognostic (4.18e-2)" "unprognostic (2.80e-2)" "unprognostic (1.11e-1)" "potential prognostic unfavorable (4.89e-4)" "unprognostic (4.04e-2)" "unprognostic (6.88e-2)" "unprognostic (2.68e-1)" "unprognostic (2.71e-2)" "unprognostic (1.39e-1)" "unprognostic (5.94e-2)" "unprognostic (1.77e-1)" "unprognostic (1.59e-1)" "unprognostic (3.52e-2)" "unprognostic (3.77e-2)" KLHL25 "ENC-2, ENC2, FLJ12587" ENSG00000183655 "Kelch like family member 25" Q9H0H3 15 85759326-85794925 "Predicted intracellular proteins" "Translation regulation, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 3.9" "Group enriched" "Detected in many" 4 "monocytes: 3.9;NK-cells: 2.6;T-cells: 1.7" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Liver - Neutrophils" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "cerebral cortex: 38.0;hippocampal formation: 21.3" HPA023450 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 1: T-cells - Unknown function" "Cluster 67: Testis - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 58: Non-specific - Nuclear processes" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 6 "Nucleoplasm, Cytosol" "HPA023450: " "unprognostic (4.89e-2)" "unprognostic (1.50e-2)" "unprognostic (3.20e-1)" "unprognostic (1.23e-1)" "unprognostic (1.34e-1)" "unprognostic (3.07e-1)" "unprognostic (1.01e-1)" "unprognostic (7.23e-3)" "unprognostic (1.02e-1)" "unprognostic (1.16e-1)" "unprognostic (3.96e-1)" "unprognostic (1.84e-2)" "unprognostic (3.25e-1)" "unprognostic (9.82e-3)" "unprognostic (1.31e-1)" "unprognostic (5.27e-2)" "unprognostic (6.18e-2)" "unprognostic (5.38e-2)" "unprognostic (8.15e-2)" "unprognostic (3.78e-2)" "unprognostic (6.10e-2)" "unprognostic (5.59e-2)" "unprognostic (4.87e-1)" "unprognostic (8.25e-3)" "unprognostic (9.14e-2)" "unprognostic (2.12e-1)" "unprognostic (2.40e-2)" "unprognostic (1.55e-1)" "unprognostic (2.84e-1)" "unprognostic (9.58e-2)" "unprognostic (1.42e-2)" KLHL26 ENSG00000167487 "Kelch like family member 26" Q53HC5 19 18637025-18671721 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 24.8" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 19.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Fibroblasts_2, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023074 Uncertain NA NA "Cluster 24: Non-specific - Transcription" "Cluster 74: Non-specific - Signal transduction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 23: Non-specific - Transcription" "Cluster 103: Non-specific - Basic cellular processes" 35 "HPA023074: " "unprognostic (6.09e-3)" "unprognostic (5.19e-2)" "potential prognostic favorable (1.08e-6)" "unprognostic (2.40e-1)" "unprognostic (1.27e-1)" "unprognostic (6.29e-2)" "unprognostic (6.18e-2)" "potential prognostic unfavorable (7.11e-6)" "unprognostic (5.39e-3)" "unprognostic (2.05e-1)" "potential prognostic favorable (1.42e-4)" "unprognostic (7.84e-3)" "unprognostic (2.01e-2)" "unprognostic (4.41e-2)" "unprognostic (2.42e-3)" "unprognostic (4.92e-3)" "unprognostic (1.92e-1)" "unprognostic (1.26e-1)" "unprognostic (2.27e-2)" "unprognostic (7.46e-3)" "unprognostic (1.64e-1)" "unprognostic (2.13e-2)" "unprognostic (1.28e-1)" "unprognostic (1.55e-1)" "unprognostic (7.41e-2)" "unprognostic (8.55e-2)" "unprognostic (3.41e-2)" "unprognostic (3.70e-2)" "unprognostic (2.40e-1)" "unprognostic (1.03e-1)" "unprognostic (8.81e-2)" KLHL28 "BTBD5, FLJ20081" ENSG00000179454 "Kelch like family member 28" Q9NXS3 14 44924324-45042322 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 25.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 618.8;Cone photoreceptor cells: 267.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000988 Approved Cytosol NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 12 Cytosol "HPA000988: " "unprognostic (1.30e-1)" "unprognostic (6.69e-2)" "unprognostic (3.01e-1)" "potential prognostic unfavorable (2.19e-4)" "unprognostic (2.58e-1)" "unprognostic (6.59e-2)" "unprognostic (9.15e-2)" "unprognostic (3.25e-3)" "unprognostic (4.53e-2)" "unprognostic (3.27e-2)" "validated prognostic favorable (2.47e-4)" "validated prognostic favorable (4.44e-4)" "unprognostic (1.02e-1)" "unprognostic (1.71e-2)" "unprognostic (2.66e-1)" "unprognostic (2.89e-1)" "unprognostic (7.39e-2)" "unprognostic (1.81e-1)" "unprognostic (1.31e-1)" "unprognostic (2.91e-2)" "unprognostic (2.87e-2)" "unprognostic (1.12e-1)" "unprognostic (4.16e-2)" "unprognostic (7.07e-2)" "unprognostic (1.19e-1)" "unprognostic (7.73e-2)" "unprognostic (1.15e-1)" "unprognostic (1.07e-1)" "unprognostic (1.03e-1)" "unprognostic (1.94e-2)" "unprognostic (4.87e-2)" KLHL29 "KBTBD9, KIAA1921" ENSG00000119771 "Kelch like family member 29" Q96CT2 2 23385179-23708611 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Lactotrophs: 672.6;Podocytes: 1938.3;Salivary myoepithelial cells: 521.7;Somatotrophs: 930.6;Thymic myoid cells: 383.4;Thyrotrophs: 418.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035237, HPA049057, HPA057379" Approved Approved Mitochondria,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 8 Mitochondria Cytosol "HPA035237: , HPA049057: , HPA057379: " "unprognostic (9.00e-3)" "unprognostic (1.84e-2)" "unprognostic (2.31e-1)" "unprognostic (3.42e-2)" "unprognostic (1.92e-1)" "unprognostic (2.10e-1)" "unprognostic (1.91e-1)" "unprognostic (9.35e-3)" "unprognostic (1.89e-2)" "unprognostic (1.56e-1)" "unprognostic (4.82e-1)" "unprognostic (1.42e-3)" "unprognostic (1.48e-2)" "unprognostic (1.19e-1)" "unprognostic (4.83e-2)" "unprognostic (3.17e-2)" "unprognostic (3.30e-1)" "unprognostic (3.40e-2)" "unprognostic (2.94e-1)" "unprognostic (1.74e-1)" "unprognostic (6.34e-3)" "unprognostic (2.42e-2)" "unprognostic (4.12e-1)" "unprognostic (1.27e-1)" "potential prognostic favorable (5.18e-4)" "unprognostic (1.37e-1)" "unprognostic (9.02e-3)" "unprognostic (6.60e-3)" "unprognostic (7.86e-2)" KLHL3 KIAA1129 ENSG00000146021 "Kelch like family member 3" Q9UH77 5 137617500-137736089 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Ubl conjugation pathway" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 44.9" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 158.9;Brain inhibitory neurons: 117.4;Cardiomyocytes: 180.9;Distal convoluted tubule cells: 668.7;Oligodendrocytes: 105.7;Renal connecting tubule cells: 149.0;Retinal pigment epithelial cells: 123.6" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 7 "Kidney Chromophobe (TCGA): 27.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Kidney - Intercalated cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051291 Approved NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 71: Cerebellum - Nervous system development" "Cluster 15: Non-specific - Transcription" "Cluster 59: Leukemia - T-cell receptor" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 29 "HPA051291: " "unprognostic (1.59e-3)" "unprognostic (8.99e-2)" "unprognostic (2.33e-1)" "unprognostic (3.62e-2)" "unprognostic (1.05e-2)" "unprognostic (1.73e-1)" "unprognostic (3.71e-1)" "unprognostic (1.96e-1)" "unprognostic (1.67e-1)" "unprognostic (2.41e-3)" "unprognostic (1.12e-2)" "unprognostic (4.66e-2)" "unprognostic (1.53e-1)" "unprognostic (3.26e-1)" "unprognostic (1.20e-1)" "unprognostic (1.23e-1)" "unprognostic (8.92e-2)" "unprognostic (1.87e-1)" "unprognostic (6.71e-3)" "unprognostic (1.73e-2)" "unprognostic (1.16e-1)" "unprognostic (9.72e-2)" "unprognostic (1.66e-1)" "unprognostic (3.16e-3)" "unprognostic (1.53e-1)" KLHL30 FLJ43374 ENSG00000168427 "Kelch like family member 30" Q0D2K2 2 238138668-238152947 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "skeletal muscle: 140.7" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 8.5;Myonuclei: 29.5;Myosatellite cells: 12.3;Thymic myoid cells: 23.1;Vascular smooth muscle cells: 9.4" "Cell type enriched" "Detected in some" 8 "vascular associated smooth muscle cell: 11.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 2.0" "Adrenal gland - Smooth muscle cells, Breast - Endothelial cells, Heart muscle - Cardiomyocytes, Spleen - Smooth muscle cells, Stomach - Fibroblasts" "Region enriched" "Detected in single" 35 "olfactory bulb: 9.4" "Not detected" "Not detected" HPA062095 Approved "Centriolar satellite" NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 44: Non-specific - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 46: Skeletal myocytes - Muscle structure & formation" "Centriolar satellite" "HPA062095: " "unprognostic (5.73e-3)" "unprognostic (9.91e-3)" "unprognostic (2.20e-1)" "unprognostic (2.58e-2)" "unprognostic (9.88e-2)" KLHL31 "bA345L23.2, BKLHD6, KBTBD1" ENSG00000124743 "Kelch like family member 31" Q9H511 6 53647916-53665756 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 47.2;skeletal muscle: 136.8;tongue: 32.6" "Group enriched" "Detected in many" 4 "Cardiomyocytes: 1297.9;Myonuclei: 488.1" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 4.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 36: Choroid plexus - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" "unprognostic (3.03e-2)" "unprognostic (1.87e-1)" KLHL32 "BKLHD5, KIAA1900" ENSG00000186231 "Kelch like family member 32" Q96NJ5 6 96924620-97140754 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 20.2;fallopian tube: 6.0" "Cell type enhanced" "Detected in many" "Astrocytes: 232.4;Bergmann glia: 408.2;Brain excitatory neurons: 172.5;Ependymal cells: 590.4;Fallopian tube ciliated cells: 182.8;Oligodendrocyte progenitor cells: 315.3;Oligodendrocytes: 883.7;Other brain neurons: 200.4;Respiratory ciliated cells: 346.8;Retinal amacrine cells: 281.3;Retinal horizontal cells: 402.7" "Cell type enhanced" "Detected in all" "oligodendrocyte: 1122.6" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 3.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 4 "B-cells: 1.0;T-cells: 2.6" "Cancer enhanced" "Detected in some" "lymphoma: 1.7;Myeloma: 1.6" "Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Skin - Eccrine sweat gland cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039150, HPA043872" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 80: Oligodendrocytes - Myelination" 4 Nucleoplasm Cytosol "HPA039150: , HPA043872: " "unprognostic (4.99e-2)" "unprognostic (1.51e-2)" "unprognostic (5.76e-2)" "unprognostic (2.08e-1)" "potential prognostic favorable (5.35e-5)" "validated prognostic favorable (9.97e-7)" "validated prognostic favorable (1.61e-4)" "unprognostic (2.37e-2)" "unprognostic (6.72e-2)" "unprognostic (2.03e-3)" "unprognostic (1.32e-2)" KLHL33 ENSG00000185271 "Kelch like family member 33" A6NCF5 14 20425852-20436166 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 33 "skeletal muscle: 68.5;tongue: 18.8" "Cell type enriched" "Detected in some" 5 "Myonuclei: 72.3" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 5.2;fibroblast: 4.8;pericyte: 2.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 22 "plasmacytoid DC: 5.8" "Lineage enriched" "Detected in single" 22 "dendritic cells: 5.8" "Cancer enhanced" "Detected in single" "Leukemia: 1.5" "Minor Salivary Gland - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Skeletal myocytes, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA049985, HPA056560" Enhanced NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 6: Leukemia - Signal transduction" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 20 "HPA049985: , HPA056560: " "unprognostic (5.80e-3)" "unprognostic (1.17e-1)" KLHL34 "FLJ34960, RP11-450P7.3" ENSG00000185915 "Kelch like family member 34" Q8N239 X 21654690-21658330 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skeletal muscle: 23.9" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 10.7;Brain inhibitory neurons: 5.2;Cone photoreceptor cells: 10.4;Müller glia: 5.3;Myonuclei: 8.8;Oocytes: 4.6;Retinal amacrine cells: 17.9;Retinal ganglion cells: 11.6;Retinal horizontal cells: 6.0;Retinal pigment epithelial cells: 8.5;Rod photoreceptor cells: 31.7" "Cell type enhanced" "Detected in many" "hippocampal CA4: 20.6;hippocampal dentate gyrus: 20.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adrenal gland - Adrenal medulla cells, Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA060287 Uncertain NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 51: Neurons - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 79: Photoreceptor cells - Phototransduction" 32 "HPA060287: " KLHL35 FLJ33790 ENSG00000149243 "Kelch like family member 35" Q6PF15 11 75422394-75433203 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.4;testis: 9.0" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 46.5;Early spermatids: 24.5;Late primary spermatocytes: 23.7;Late spermatids: 39.1;Oocytes: 59.9;Platelets: 26.8;Retinal bipolar cells: 25.5;Undifferentiated spermatogonia: 73.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 2.6" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039864, HPA070736" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Centrosome" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 78: Brain - Neuronal signaling" "Cluster 24: Neurons - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 7 "Nucleoplasm, Centrosome" "Nucleoli fibrillar center" "HPA039864: , HPA070736: " "unprognostic (1.51e-1)" "unprognostic (1.80e-1)" "unprognostic (5.13e-3)" "unprognostic (9.01e-3)" "unprognostic (2.72e-2)" "potential prognostic unfavorable (4.47e-5)" "unprognostic (8.98e-2)" "unprognostic (1.76e-3)" "unprognostic (7.16e-3)" "unprognostic (6.77e-3)" "unprognostic (6.97e-2)" "unprognostic (2.15e-1)" "unprognostic (1.02e-1)" "unprognostic (2.11e-1)" "unprognostic (4.56e-1)" "unprognostic (1.15e-2)" "unprognostic (3.71e-2)" "unprognostic (8.86e-2)" "unprognostic (2.21e-1)" "unprognostic (2.28e-1)" "unprognostic (1.68e-1)" "unprognostic (8.42e-3)" "unprognostic (6.07e-2)" KLHL36 "C16orf44, FLJ12543" ENSG00000135686 "Kelch like family member 36" Q8N4N3 16 84648511-84667686 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Macrophages, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023423 Approved Approved Cytosol NA NA "Cluster 41: Basophils - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 110: Mural cells - ECM organization" 6 Cytosol "HPA023423: " "unprognostic (2.12e-1)" "unprognostic (1.26e-2)" "unprognostic (3.74e-2)" "unprognostic (8.24e-3)" "unprognostic (3.60e-1)" "unprognostic (8.50e-2)" "unprognostic (1.70e-1)" "unprognostic (4.41e-2)" "unprognostic (9.54e-2)" "unprognostic (1.49e-1)" "potential prognostic favorable (5.89e-11)" "unprognostic (2.91e-2)" "unprognostic (8.55e-3)" "unprognostic (5.31e-2)" "unprognostic (2.45e-2)" "unprognostic (1.27e-2)" "unprognostic (3.49e-2)" "unprognostic (6.06e-3)" "unprognostic (4.08e-1)" "unprognostic (1.60e-2)" "unprognostic (1.46e-2)" "unprognostic (3.65e-2)" "unprognostic (1.13e-1)" "unprognostic (2.39e-1)" "unprognostic (6.36e-2)" "unprognostic (9.34e-2)" "unprognostic (1.77e-1)" "unprognostic (1.39e-1)" "unprognostic (1.81e-1)" "unprognostic (2.83e-2)" "unprognostic (8.95e-2)" KLHL38 C8ORFK36 ENSG00000175946 "Kelch like family member 38" Q2WGJ6 8 123644442-123653801 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 50.8;skeletal muscle: 238.4;tongue: 66.4" "Group enriched" "Detected in some" 16 "Cardiomyocytes: 44.1;Myonuclei: 25.9;Thymic myoid cells: 21.8" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Breast Invasive Carcinoma (TCGA): 1.8;Skin Cutaneous Melanoma (TCGA): 2.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA024770, HPA027115" Uncertain Approved Nucleoplasm,Cytosol Yes NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 53: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 55: Myocytes - Oxidative muscle function" 72 Nucleoplasm Cytosol "HPA024770: , HPA027115: " "unprognostic (5.99e-2)" "unprognostic (3.51e-1)" "unprognostic (1.67e-1)" KLHL4 "DKELCHL, KHL4, KIAA1687" ENSG00000102271 "Kelch like family member 4" Q9C0H6 X 87517409-87670050 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 23.1;brain: 9.6;ovary: 9.6" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 366.9;Cone photoreceptor cells: 93.2;Lymphatic endothelial cells: 234.8;Mesothelial cells: 105.3;Oligodendrocyte progenitor cells: 75.9;Oligodendrocytes: 325.6;Ovarian stromal cells: 58.6;Sertoli cells: 405.5" "Cell type enhanced" "Detected in many" "oligodendrocyte: 441.8" "Cancer enriched" "Detected in some" 9 "Glioblastoma Multiforme (TCGA): 16.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 16.4" "Adrenal gland - Adrenal cortex cells, Lung - Fibroblasts_2, Prostate - Smooth muscle cells, Skeletal muscle - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029192 Approved Supported "Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Centriolar satellite,Centrosome,Basal body" Yes NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 6 "Microtubules, Primary cilium" "Cytokinetic bridge, Mitotic spindle, Centriolar satellite, Centrosome, Basal body" "HPA029192: " "unprognostic (3.51e-2)" "unprognostic (1.13e-2)" "unprognostic (1.74e-2)" "unprognostic (1.93e-3)" "potential prognostic unfavorable (1.46e-4)" "unprognostic (4.96e-2)" "unprognostic (3.33e-1)" "unprognostic (4.59e-3)" "unprognostic (2.65e-3)" KLHL40 "KBTBD5, NEM8, SRYP" ENSG00000157119 "Kelch like family member 40" Q2TBA0 3 42685537-42692544 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Developmental protein" "Disease variant, Nemaline myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 64 "skeletal muscle: 417.9;tongue: 151.4" "Cell type enriched" "Detected in some" 4 "Thymic myoid cells: 130.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Head and Neck Squamous Cell Carcinoma (TCGA): 1.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA024463, HPA052201" Enhanced NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 11: White matter - Signal transduction" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 6 "HPA024463: , HPA052201: " "unprognostic (4.05e-2)" KLHL41 "KBTBD10, Krp1, SARCOSIN" ENSG00000239474 "Kelch like family member 41" O60662 2 169509702-169526258 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Nemaline myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 42 "skeletal muscle: 4718.5;tongue: 3245.2" "Cell type enriched" "Detected in some" 7 "Thymic myoid cells: 492.2" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in some" 8 "Head and Neck Squamous Cell Carcinoma (TCGA): 27.1;Prostate Adenocarcinoma (TCGA): 7.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 10 "Sarcoma: 16.3" "Pituitary gland - Gonadotropes, Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA021165, HPA021753, HPA021760" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 12000 "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 10 Cytosol "Nucleoplasm, Plasma membrane" "HPA021165: , HPA021753: , HPA021760: " "unprognostic (1.07e-1)" "unprognostic (3.06e-1)" "unprognostic (4.00e-3)" "potential prognostic favorable (3.34e-4)" "unprognostic (2.49e-1)" "unprognostic (2.66e-1)" "unprognostic (1.65e-3)" KLHL42 "Ctb9, KIAA1340, KLHDC5" ENSG00000087448 "Kelch like family member 42" Q9P2K6 12 27780048-27803040 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Peritubular myoid cells: 221.9;Podocytes: 260.7;Sertoli cells: 194.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020979 Uncertain NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 74: Non-specific - Signal transduction" "Cluster 34: Non-specific - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 62: Smooth muscle cells - Muscle contraction" 36 "HPA020979: " "unprognostic (1.49e-2)" "unprognostic (1.77e-2)" "unprognostic (1.22e-3)" "unprognostic (3.31e-1)" "unprognostic (4.83e-3)" "unprognostic (8.91e-2)" "unprognostic (2.52e-3)" "unprognostic (5.67e-2)" "unprognostic (2.11e-2)" "unprognostic (1.57e-1)" "unprognostic (2.14e-1)" "unprognostic (2.49e-3)" "unprognostic (4.10e-2)" "unprognostic (2.26e-3)" "unprognostic (2.09e-1)" "unprognostic (1.00e-1)" "unprognostic (4.59e-2)" "unprognostic (4.89e-2)" "unprognostic (1.88e-1)" "unprognostic (1.36e-1)" "unprognostic (2.01e-2)" "unprognostic (2.25e-1)" "unprognostic (2.61e-2)" "unprognostic (7.69e-3)" "unprognostic (1.61e-1)" "unprognostic (1.88e-1)" "unprognostic (9.67e-2)" "unprognostic (1.26e-2)" "unprognostic (1.72e-1)" KLHL5 ENSG00000109790 "Kelch like family member 5" Q96PQ7 4 39045039-39126857 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglia: 371.0;Retinal amacrine cells: 342.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Prostate - Smooth muscle cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013958, HPA079699" Approved Approved "Plasma membrane,Microtubules" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 4 "Plasma membrane, Microtubules" "HPA013958: , HPA079699: " "unprognostic (6.08e-2)" "unprognostic (2.39e-1)" "unprognostic (4.70e-1)" "unprognostic (9.11e-2)" "unprognostic (7.85e-2)" "unprognostic (1.76e-1)" "unprognostic (1.56e-1)" "unprognostic (2.45e-1)" "unprognostic (1.96e-1)" "unprognostic (1.14e-1)" "validated prognostic favorable (1.67e-7)" "validated prognostic favorable (8.87e-4)" "unprognostic (2.61e-2)" "unprognostic (2.35e-2)" "unprognostic (4.73e-2)" "unprognostic (6.26e-3)" "unprognostic (1.46e-3)" "unprognostic (1.73e-1)" "unprognostic (1.99e-1)" "unprognostic (6.88e-2)" "unprognostic (3.95e-2)" "unprognostic (3.50e-2)" "unprognostic (3.52e-3)" "unprognostic (4.47e-2)" "unprognostic (5.19e-1)" "unprognostic (1.21e-2)" "unprognostic (9.70e-2)" "unprognostic (2.45e-2)" "unprognostic (1.21e-1)" "unprognostic (6.03e-2)" "unprognostic (2.57e-1)" KLHL6 FLJ00029 ENSG00000172578 "Kelch like family member 6" Q8WZ60 3 183487551-183555706 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "lymphoid tissue: 29.1" "Cell type enhanced" "Detected in many" "B-cells: 134.0;cDC: 126.9;Hematopoietic stem cells: 83.5;Innate lymphoid cells: 109.4;Kupffer cells: 59.4;Macrophages: 134.5;Mast cells: 74.6;Microglia: 69.6;monocytes: 92.9;Neutrophils: 63.9;NK-cells: 61.0;pDCs: 78.2;Plasma cells: 284.5;Platelets: 168.1;Respiratory ciliated cells: 90.2;Thymocytes: 87.2" "Group enriched" "Detected in some" 9 "central nervous system macrophage: 95.1;leukocyte: 48.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 78 "Leukemia: 13.6;lymphoma: 35.9;Myeloma: 27.1" "Adipose visceral - T-cells, Minor Salivary Gland - Plasma cells, Prostate - T-cells, Spleen - B-cells (Spleen), Stomach - Plasma cells" "Low region specificity" "Detected in all" HPA024512 Uncertain Approved "Plasma membrane,Microtubules,Mitotic spindle,Centriolar satellite,Cytosol" Yes NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 12 "Plasma membrane, Centriolar satellite" "Microtubules, Mitotic spindle, Cytosol" "HPA024512: " "unprognostic (4.66e-2)" "unprognostic (6.01e-2)" "unprognostic (2.23e-1)" "unprognostic (5.14e-3)" "unprognostic (2.41e-1)" "unprognostic (7.30e-2)" "unprognostic (7.59e-2)" "unprognostic (5.97e-1)" "potential prognostic favorable (3.13e-4)" "unprognostic (1.13e-1)" "unprognostic (2.60e-2)" "unprognostic (1.97e-1)" "unprognostic (2.24e-2)" "potential prognostic favorable (3.80e-4)" "unprognostic (7.88e-2)" "unprognostic (5.34e-2)" "unprognostic (3.49e-1)" "unprognostic (4.90e-1)" "unprognostic (5.88e-2)" "unprognostic (4.81e-2)" "unprognostic (6.24e-2)" "unprognostic (4.88e-1)" "unprognostic (3.85e-1)" "unprognostic (1.45e-1)" "unprognostic (3.06e-1)" KLHL7 "KLHL6, RP42, SBBI26" ENSG00000122550 "Kelch like family member 7" Q8IXQ5 7 23105758-23177914 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 47.5" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 302.5;Early spermatids: 757.5;Late primary spermatocytes: 295.8;Late spermatids: 382.0;Oocytes: 248.7;Sertoli cells: 322.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029491, HPA029492" Uncertain Enhanced "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 35: Non-specific - Mixed function" "Cluster 2: Neurons - Nucleosome" "Cluster 67: Non-specific - Unknown function" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 10 "Nucleoplasm, Cytosol" "Plasma membrane" "HPA029491: , HPA029492: " "unprognostic (8.02e-2)" "unprognostic (2.17e-2)" "unprognostic (7.36e-2)" "unprognostic (1.48e-1)" "unprognostic (5.11e-2)" "unprognostic (1.63e-1)" "unprognostic (3.74e-2)" "unprognostic (2.76e-2)" "unprognostic (4.35e-3)" "unprognostic (2.85e-3)" "unprognostic (1.73e-2)" "unprognostic (1.41e-1)" "unprognostic (2.24e-1)" "potential prognostic unfavorable (3.70e-5)" "unprognostic (3.98e-2)" "unprognostic (1.96e-2)" "unprognostic (2.03e-1)" "unprognostic (8.74e-2)" "unprognostic (6.85e-2)" "unprognostic (4.06e-3)" "unprognostic (3.72e-2)" "unprognostic (8.51e-2)" "potential prognostic unfavorable (9.25e-4)" "unprognostic (3.59e-2)" "unprognostic (1.24e-1)" "unprognostic (3.83e-2)" "unprognostic (9.04e-3)" "unprognostic (1.21e-1)" "unprognostic (8.36e-2)" "unprognostic (1.17e-2)" "unprognostic (2.85e-1)" KLHL8 KIAA1378 ENSG00000145332 "Kelch like family member 8" Q9P2G9 4 87160103-87240314 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 57.1" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 323.2;Müller glia: 595.5;Neutrophils: 282.4;Renal collecting duct principal cells: 310.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Macrophages, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013856, HPA017762" Approved Enhanced Nucleoplasm NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 22: Epididymis - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 11: Neuronal - Sensory perception" "Cluster 11: Muller glia cells - Retinal homeostasis" 37 Nucleoplasm "HPA013856: , HPA017762: " "unprognostic (2.95e-1)" "unprognostic (1.86e-2)" "unprognostic (8.47e-2)" "unprognostic (1.68e-1)" "unprognostic (4.41e-2)" "unprognostic (1.05e-2)" "unprognostic (7.58e-2)" "unprognostic (1.20e-1)" "unprognostic (1.04e-2)" "unprognostic (5.56e-3)" "potential prognostic favorable (1.59e-7)" "unprognostic (1.43e-3)" "unprognostic (7.62e-2)" "unprognostic (1.21e-1)" "unprognostic (8.62e-2)" "unprognostic (6.83e-2)" "unprognostic (4.24e-1)" "unprognostic (2.24e-1)" "unprognostic (4.59e-2)" "unprognostic (1.56e-2)" "unprognostic (3.59e-3)" "unprognostic (2.59e-1)" "unprognostic (1.93e-1)" "unprognostic (1.12e-1)" "unprognostic (1.81e-2)" "unprognostic (1.08e-1)" "unprognostic (2.91e-2)" "unprognostic (8.86e-3)" "unprognostic (1.89e-1)" "unprognostic (3.43e-3)" "unprognostic (1.03e-1)" KLHL9 "FLJ13568, KIAA1354" ENSG00000198642 "Kelch like family member 9" Q9P2J3 9 21329665-21335404 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046039, HPA059901" Approved Approved Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 17: Non-specific - RNA processing" 50 Cytosol "HPA046039: , HPA059901: " "unprognostic (6.62e-2)" "unprognostic (1.25e-2)" "unprognostic (3.77e-1)" "unprognostic (4.39e-1)" "unprognostic (1.11e-1)" "unprognostic (1.59e-1)" "unprognostic (1.91e-1)" "potential prognostic favorable (7.07e-4)" "unprognostic (2.59e-1)" "unprognostic (2.91e-2)" "potential prognostic favorable (2.69e-9)" "unprognostic (6.63e-3)" "unprognostic (4.06e-2)" "unprognostic (8.06e-2)" "unprognostic (2.52e-1)" "unprognostic (1.43e-1)" "unprognostic (5.95e-2)" "unprognostic (3.92e-1)" "unprognostic (8.84e-2)" "unprognostic (2.70e-1)" "unprognostic (1.00e-1)" "unprognostic (1.84e-2)" "unprognostic (1.97e-2)" "unprognostic (1.62e-1)" "unprognostic (2.09e-2)" "unprognostic (1.09e-1)" "unprognostic (8.50e-2)" "unprognostic (8.95e-2)" "unprognostic (2.71e-1)" "unprognostic (2.06e-1)" "unprognostic (1.41e-1)" KLK1 Klk6 ENSG00000167748 "Kallikrein 1" P06870 19 50819146-50823787 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 77 "pancreas: 9013.3;salivary gland: 5169.3" "Group enriched" "Detected in many" 4 "Goblet cells: 1406.0;Pancreatic acinar cells: 4929.0" "Cell type enhanced" "Detected in single" "fibroblast: 1.1" "Cancer enriched" "Detected in many" 16 "Kidney Chromophobe (TCGA): 2586.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "memory B-cell: 9.5;naive B-cell: 4.0" "Lineage enriched" "Detected in single" 13 "B-cells: 9.5" "Cancer enriched" "Detected in some" 4 "colorectal cancer: 12.3" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Pancreas - Exocrine glandular cells, Prostate - Prostate glandular cells, Spleen - B-cells (Spleen)" "Region enhanced" "Detected in many" "cerebral cortex: 9.1" HPA059690 Approved "Secreted to digestive system" Enzyme NA NA 11000000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 8: Pancreas - Proteolysis" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Pancreatic acinar cells - Pancreatic exocrine secretion" 14 "HPA059690: " "unprognostic (2.17e-1)" "unprognostic (7.66e-2)" "unprognostic (8.73e-3)" "unprognostic (1.54e-1)" "unprognostic (1.68e-1)" "unprognostic (5.90e-2)" "unprognostic (1.02e-2)" "unprognostic (1.52e-2)" "potential prognostic unfavorable (7.13e-4)" "unprognostic (8.64e-2)" "unprognostic (2.59e-2)" "unprognostic (3.25e-3)" "unprognostic (3.47e-1)" "unprognostic (1.31e-1)" "unprognostic (7.97e-2)" "unprognostic (9.44e-2)" "unprognostic (9.13e-2)" "potential prognostic unfavorable (2.16e-4)" "unprognostic (1.56e-1)" "unprognostic (1.39e-1)" "unprognostic (3.74e-1)" KLK10 "NES1, PRSSL1" ENSG00000129451 "Kallikrein related peptidase 10" O43240 19 51012739-51020175 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Cell cycle" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "cervix: 45.7;esophagus: 136.1;vagina: 60.0" "Cell type enriched" "Detected in many" 4 "Esophageal apical cells: 2128.8" "Cell type enhanced" "Detected in many" "lower rhombic lip: 23.4" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 116.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 80.0;pancreatic cancer: 79.5" "Adipose visceral - Mesothelial cells, Prostate - Prostate basal glandular cells" "Region enriched" "Detected in single" 4 "hippocampal formation: 1.6" "Not detected" "Not detected" "Secreted in other tissues" Enzyme NA NA 5900000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 115 "unprognostic (7.94e-3)" "potential prognostic favorable (3.27e-4)" "unprognostic (1.61e-1)" "unprognostic (2.04e-1)" "unprognostic (2.36e-1)" "unprognostic (2.83e-1)" "unprognostic (8.98e-2)" "unprognostic (5.36e-1)" "unprognostic (1.07e-1)" "unprognostic (1.65e-1)" "unprognostic (2.28e-2)" "unprognostic (3.98e-2)" "unprognostic (1.11e-2)" "unprognostic (1.54e-1)" "potential prognostic unfavorable (1.81e-4)" "unprognostic (6.21e-2)" "unprognostic (4.46e-2)" "unprognostic (2.97e-1)" "unprognostic (1.57e-1)" "unprognostic (2.48e-1)" "unprognostic (3.37e-2)" "unprognostic (9.55e-2)" "unprognostic (1.06e-2)" "unprognostic (2.19e-1)" KLK11 "PRSS20, TLSP" ENSG00000167757 "Kallikrein related peptidase 11" Q9UBX7 19 51022216-51028039 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 311.1;skin 1: 229.8;vagina: 179.1" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 2907.0;Esophageal suprabasal cells: 1082.2;Late spermatids: 531.4;Parietal cells: 236.9;Respiratory secretory cells: 391.8;Suprabasal keratinocytes: 484.4" "Cell type enriched" "Detected in some" 15 "choroid plexus epithelial cell: 39.9" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 211.9" "Region enriched" "Detected in some" 26 "choroid plexus: 96.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 61.5;thyroid cancer: 43.0" "Adipose visceral - Mesothelial cells, Skin - Keratinocyte (other), Stomach - Parietal cells, Testis - Late spermatids" "Not detected" "Not detected" "Region enriched" "Detected in single" 4 "basal ganglia: 1.0" CAB026340 Approved "Secreted in other tissues" Enzyme NA NA 18000000 "Cluster 11: Esophagus - Basic cellular processes" "Cluster 36: Choroid plexus - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 85: Squamous epithelial cells - Keratinization" "CAB026340: " "unprognostic (1.50e-1)" "unprognostic (4.87e-2)" "unprognostic (8.51e-2)" "unprognostic (6.34e-2)" "unprognostic (1.40e-1)" "unprognostic (1.82e-2)" "unprognostic (3.64e-2)" "unprognostic (2.45e-1)" "unprognostic (2.69e-1)" "unprognostic (3.14e-1)" "potential prognostic favorable (2.12e-4)" "unprognostic (3.09e-1)" "unprognostic (3.06e-2)" "unprognostic (1.35e-1)" "unprognostic (1.60e-1)" "unprognostic (1.67e-1)" "validated prognostic unfavorable (7.44e-5)" "validated prognostic unfavorable (7.90e-4)" "unprognostic (2.09e-1)" "unprognostic (3.58e-1)" "unprognostic (9.35e-3)" "unprognostic (2.76e-1)" "unprognostic (3.60e-2)" "unprognostic (1.56e-1)" "unprognostic (3.46e-2)" "unprognostic (8.25e-2)" KLK12 KLK-L5 ENSG00000186474 "Kallikrein related peptidase 12" Q9UKR0 19 51029092-51035230 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "cervix: 25.1;esophagus: 77.6;salivary gland: 33.6;vagina: 35.2" "Cell type enriched" "Detected in some" 18 "Esophageal apical cells: 5676.9" "Cell type enriched" "Detected in single" 47 "choroid plexus epithelial cell: 6.6" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 39.1;Lung Adenocarcinoma (TCGA): 56.4" "Region enriched" "Detected in single" 18 "choroid plexus: 4.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 6.1" "Adipose visceral - Mesothelial cells, Lung - Respiratory ciliated cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" CAB025473 Uncertain "Secreted in other tissues" Enzyme NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 84: Apical squamous epithelium - Cornification" "CAB025473: " "unprognostic (4.72e-1)" "unprognostic (2.92e-1)" "unprognostic (3.54e-1)" "unprognostic (1.13e-1)" "unprognostic (5.40e-3)" "unprognostic (8.44e-3)" "unprognostic (4.90e-3)" "potential prognostic favorable (6.55e-4)" "unprognostic (2.84e-2)" "unprognostic (1.37e-1)" "unprognostic (1.27e-1)" "unprognostic (6.26e-2)" "unprognostic (5.00e-1)" "unprognostic (2.09e-1)" "unprognostic (7.51e-2)" "unprognostic (5.25e-2)" "unprognostic (3.83e-1)" "unprognostic (1.45e-1)" "potential prognostic favorable (1.23e-5)" "unprognostic (6.30e-2)" KLK13 KLK-L4 ENSG00000167759 "Kallikrein related peptidase 13" Q9UKR3 19 51055626-51065114 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 145.2;esophagus: 739.7;vagina: 186.7" "Cell type enriched" "Detected in some" 13 "Esophageal apical cells: 9818.9" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 54.6;Head and Neck Squamous Cell Carcinoma (TCGA): 90.3;Skin Cutaneous Melanoma (TCGA): 26.6" "Region enhanced" "Detected in single" "choroid plexus: 1.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 11.1;Esophageal cancer: 5.4;ovarian cancer: 6.6" "Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary gland basal cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA062136 Enhanced "Secreted in other tissues" Enzyme NA NA 8000000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 44: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 84: Apical squamous epithelium - Cornification" 3 "HPA062136: " "unprognostic (2.51e-1)" "unprognostic (1.06e-2)" "potential prognostic favorable (7.88e-4)" "unprognostic (2.80e-2)" "unprognostic (2.33e-1)" "unprognostic (9.56e-2)" "unprognostic (1.33e-3)" "unprognostic (1.89e-1)" "unprognostic (1.70e-2)" "unprognostic (2.72e-1)" "unprognostic (1.95e-1)" "unprognostic (1.90e-1)" "potential prognostic unfavorable (5.76e-4)" "unprognostic (1.26e-2)" "unprognostic (1.83e-2)" "unprognostic (2.89e-1)" "unprognostic (8.01e-2)" "unprognostic (5.53e-1)" "unprognostic (9.99e-2)" "unprognostic (2.08e-1)" KLK14 KLK-L6 ENSG00000129437 "Kallikrein related peptidase 14" Q9P0G3 19 51077495-51084245 "Cancer-related genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skin 1: 9.9" "Cell type enhanced" "Detected in some" "Breast hormone-responsive cells: 5.5;Respiratory secretory cells: 3.7;Suprabasal keratinocytes: 3.5;Transitional alveolar cells: 2.3;Tuft cells: 11.5" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 39.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 7.8;head and neck cancer: 6.4" "Lung - Respiratory ciliated cells" "Not detected" "Not detected" "Not detected" "Not detected" CAB026228 Uncertain "Secreted in other tissues" Enzyme NA NA "Cluster 37: Skin - Keratinization" "Cluster 37: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" "CAB026228: " "unprognostic (2.45e-2)" "unprognostic (3.99e-2)" "unprognostic (9.28e-2)" "unprognostic (3.48e-2)" "unprognostic (3.59e-1)" "unprognostic (7.52e-3)" "unprognostic (1.71e-1)" "unprognostic (4.12e-2)" "unprognostic (2.34e-1)" "unprognostic (5.61e-2)" "unprognostic (1.75e-1)" "unprognostic (7.35e-2)" "unprognostic (1.24e-1)" "unprognostic (2.87e-1)" "unprognostic (7.32e-3)" "unprognostic (2.06e-1)" "unprognostic (2.20e-1)" "potential prognostic unfavorable (4.28e-4)" "unprognostic (1.79e-2)" "unprognostic (3.68e-1)" "unprognostic (1.18e-1)" "unprognostic (7.33e-2)" KLK15 "ACO, HSRNASPH, prostinogen" ENSG00000174562 "Kallikrein related peptidase 15" Q9H2R5 19 50825289-50837213 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 2.1;salivary gland: 3.7;testis: 1.1" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 6.9;Early primary spermatocytes: 15.5;Early spermatids: 6.0;Enteric stem cells: 5.5;Goblet cells: 45.0;Late primary spermatocytes: 17.6;Late spermatids: 13.9;Retinal horizontal cells: 8.0;Salivary duct cells: 14.2;Salivary ionocytes: 7.6;Undifferentiated spermatogonia: 6.2" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Kidney Chromophobe (TCGA): 38.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "prostate cancer: 2.4" "Colon - Colon enterocytes, Prostate - Prostate glandular cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA019802 Uncertain "Secreted to blood" Enzyme NA NA "Cluster 60: Stomach - Digestion" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 70: Intestinal goblet cells - Mucin production" 84 "HPA019802: " "unprognostic (1.41e-1)" "unprognostic (2.45e-1)" "unprognostic (1.63e-1)" "unprognostic (1.21e-1)" "unprognostic (1.09e-1)" "unprognostic (2.24e-1)" "unprognostic (6.95e-3)" KLK2 ENSG00000167751 "Kallikrein related peptidase 2" P20151 19 50861568-50880567 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 86 "prostate: 530.8" "Cell type enriched" "Detected in some" 92 "Prostatic glandular cells: 7044.4" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 384 "Prostate Adenocarcinoma (TCGA): 752.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in many" 134 "prostate cancer: 207.3" "Prostate - Prostate glandular cells" HPA000764 Supported "Secreted in male reproductive system" Enzyme NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 48: Non-specific - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 1 "HPA000764: " "unprognostic (1.41e-1)" "unprognostic (1.87e-1)" "unprognostic (8.66e-3)" "unprognostic (6.50e-2)" "unprognostic (9.50e-2)" "unprognostic (1.92e-1)" "unprognostic (4.19e-1)" "unprognostic (1.02e-2)" "unprognostic (2.47e-1)" "unprognostic (9.42e-3)" "unprognostic (3.28e-1)" "unprognostic (4.48e-1)" "unprognostic (4.36e-3)" KLK3 "APS, PSA" ENSG00000142515 "Kallikrein related peptidase 3" P07288 19 50854915-50860764 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 318 "prostate: 7518.2" "Cell type enriched" "Detected in some" 147 "Prostatic glandular cells: 23233.5" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 1441 "Prostate Adenocarcinoma (TCGA): 19654.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 1800 "prostate cancer: 2405.5" "Kidney - Intercalated cells, Minor Salivary Gland - Minor salivary gland ductal cells, Prostate - Prostate glandular cells, Testis - Late spermatids" "CAB000070, HPA000764" Enhanced "Secreted in male reproductive system" Enzyme NA NA 9700000 "Cluster 38: Non-specific - Basic cellular processes" "Cluster 60: Prostate cancer - Unknown function" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 22 "CAB000070: , HPA000764: " "unprognostic (3.82e-2)" "unprognostic (1.29e-1)" "unprognostic (9.69e-2)" "unprognostic (1.18e-1)" "unprognostic (3.01e-1)" "unprognostic (5.88e-1)" "unprognostic (8.51e-2)" "unprognostic (8.70e-2)" "unprognostic (1.53e-1)" "potential prognostic unfavorable (4.00e-4)" "unprognostic (2.44e-1)" "unprognostic (2.76e-1)" "unprognostic (5.53e-2)" KLK4 "EMSP, EMSP1, KLK-L1, PRSS17, PSTS" ENSG00000167749 "Kallikrein related peptidase 4" Q9Y5K2 19 50906351-50911395 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" Biomineralization "Hydrolase, Protease, Serine protease" "Amelogenesis imperfecta, Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 33 "prostate: 260.1" "Group enriched" "Detected in some" 13 "Epididymal efferent duct absorptive cells: 214.0;Prostatic glandular cells: 517.5" "Group enriched" "Detected in some" 4 "cerebellar inhibitory: 4.3;deep-layer near-projecting: 1.3;lower rhombic lip: 3.0;splatter: 1.9" "Cancer enriched" "Detected in many" 8 "Prostate Adenocarcinoma (TCGA): 1006.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 16 "prostate cancer: 107.3" "Prostate - Prostate glandular cells" "Not detected" "Not detected" "Region enhanced" "Detected in many" "spinal cord: 5.9" HPA051839 Enhanced "Secreted in male reproductive system" Enzyme NA NA "Cluster 38: Non-specific - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 3 "HPA051839: " "unprognostic (1.57e-1)" "unprognostic (2.46e-1)" "unprognostic (6.85e-2)" "unprognostic (1.03e-3)" "unprognostic (2.16e-3)" "unprognostic (1.38e-1)" "unprognostic (1.99e-1)" "unprognostic (4.00e-2)" "potential prognostic unfavorable (5.40e-6)" "unprognostic (2.47e-2)" "unprognostic (3.47e-1)" "unprognostic (4.05e-1)" "unprognostic (1.87e-2)" "unprognostic (3.51e-1)" "unprognostic (7.95e-3)" "potential prognostic favorable (2.19e-5)" "unprognostic (8.76e-3)" "unprognostic (2.48e-2)" "unprognostic (5.70e-2)" "unprognostic (5.80e-2)" "unprognostic (1.83e-1)" "unprognostic (1.48e-1)" "unprognostic (2.10e-1)" "unprognostic (8.14e-2)" "unprognostic (6.43e-3)" "unprognostic (2.23e-1)" KLK5 "KLK-L2, SCTE" ENSG00000167754 "Kallikrein related peptidase 5" Q9Y337 19 50943303-50953093 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "skin 1: 195.5" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 35.1;Breast myoepithelial cells: 103.3;Breast secretory cells: 153.3;Early spermatids: 153.7;Esophageal apical cells: 72.4;Late spermatids: 351.6;Salivary acinar cells: 49.3;Salivary duct cells: 69.2" "Low cell type specificity" "Detected in some" "Group enriched" "Detected in many" 4 "Head and Neck Squamous Cell Carcinoma (TCGA): 121.3;Ovary Serous Cystadenocarcinoma (TCGA): 177.7;Skin Cutaneous Melanoma (TCGA): 64.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 132.4;head and neck cancer: 188.7" "Adipose visceral - Mesothelial cells, Skin - Keratinocyte (granular), Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA014343, CAB025503, CAB026341, HPA073512" Enhanced "Secreted in other tissues" Enzyme NA NA 13000000 "Cluster 37: Skin - Keratinization" "Cluster 24: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 48 "CAB025503: , CAB026341: , HPA014343: , HPA073512: " "unprognostic (1.15e-3)" "unprognostic (2.12e-2)" "unprognostic (3.22e-1)" "unprognostic (2.96e-1)" "unprognostic (3.35e-1)" "unprognostic (1.49e-3)" "unprognostic (2.23e-2)" "unprognostic (1.33e-3)" "unprognostic (2.87e-1)" "unprognostic (3.86e-2)" "unprognostic (1.01e-2)" "unprognostic (7.00e-2)" "unprognostic (1.54e-1)" "unprognostic (3.27e-1)" "unprognostic (3.52e-1)" "unprognostic (7.38e-3)" "unprognostic (6.48e-3)" KLK6 "Bssp, Klk7, neurosin, PRSS18, PRSS9" ENSG00000167755 "Kallikrein related peptidase 6" Q92876 19 50958631-50969673 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 492.8" "Group enriched" "Detected in some" 6 "Esophageal apical cells: 1278.5;Salivary duct cells: 411.2" "Cell type enriched" "Detected in many" 6 "oligodendrocyte: 183.5" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 243.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 650.6;Gallbladder cancer: 349.4" "Adipose visceral - Mesothelial cells, Kidney - Podocytes" "Region enhanced" "Detected in all" "pons and medulla: 167.9" "Region enhanced" "Detected in all" "spinal cord: 448.7" HPA051837 Supported "Nucleoplasm,Nuclear membrane,Cytokinetic bridge" "Secreted in other tissues" Enzyme Yes No 7600000 "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 84: Apical squamous epithelium - Cornification" 112 Nucleoplasm "Nuclear membrane, Cytokinetic bridge" "HPA051837: " "unprognostic (1.21e-2)" "unprognostic (2.76e-2)" "unprognostic (2.87e-1)" "unprognostic (3.18e-1)" "unprognostic (1.26e-1)" "unprognostic (1.18e-2)" "unprognostic (7.63e-2)" "unprognostic (5.11e-1)" "unprognostic (3.18e-1)" "potential prognostic unfavorable (1.77e-5)" "unprognostic (3.42e-3)" "unprognostic (5.19e-2)" "unprognostic (4.17e-3)" "unprognostic (6.25e-2)" "unprognostic (1.26e-1)" "unprognostic (2.16e-1)" "potential prognostic unfavorable (7.75e-4)" "unprognostic (5.31e-3)" "unprognostic (1.00e-2)" "unprognostic (3.79e-2)" "unprognostic (1.96e-1)" "unprognostic (1.31e-1)" "unprognostic (1.93e-1)" "unprognostic (9.81e-2)" "unprognostic (2.25e-2)" KLK7 "PRSS6, SCCE" ENSG00000169035 "Kallikrein related peptidase 7" P49862 19 50976468-50984099 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 90.8;skin 1: 189.2" "Group enriched" "Detected in some" 4 "Esophageal apical cells: 1071.4;Salivary duct cells: 306.6" "Cell type enhanced" "Detected in some" "deep-layer intratelencephalic: 12.6;hippocampal CA4: 18.6;lower rhombic lip: 9.3" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 241.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Bile duct cancer: 63.9;colorectal cancer: 23.3;Gastric cancer: 17.6;head and neck cancer: 31.1;ovarian cancer: 27.9" "Adipose visceral - Mesothelial cells, Kidney - Podocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018994, CAB026342, HPA062126" Enhanced Supported "Nuclear membrane,Plasma membrane" "Secreted in other tissues" Enzyme NA NA 7300000 "Cluster 58: Skin - Keratinization" "Cluster 24: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 84: Apical squamous epithelium - Cornification" "Plasma membrane" "Nuclear membrane" "CAB026342: , HPA018994: , HPA062126: " "unprognostic (9.81e-2)" "unprognostic (2.24e-2)" "unprognostic (6.01e-2)" "unprognostic (1.19e-1)" "unprognostic (8.42e-2)" "potential prognostic favorable (1.42e-4)" "unprognostic (1.94e-1)" "unprognostic (1.29e-2)" "unprognostic (3.03e-1)" "unprognostic (1.30e-2)" "unprognostic (8.15e-2)" "unprognostic (2.55e-2)" "unprognostic (1.96e-1)" "potential prognostic unfavorable (7.47e-5)" "unprognostic (2.27e-1)" "unprognostic (2.18e-1)" "unprognostic (1.61e-2)" "unprognostic (1.72e-1)" "unprognostic (1.88e-1)" "unprognostic (3.75e-1)" "unprognostic (1.38e-2)" "unprognostic (8.22e-2)" KLK8 "HNP, neuropsin, ovasin, PRSS19, TADG14" ENSG00000129455 "Kallikrein related peptidase 8" O60259 19 50996007-51002711 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "cervix: 41.5;esophagus: 115.9;skin 1: 96.5;vagina: 47.8" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 40.9;Breast lactating cells: 19.7;Breast secretory cells: 23.6;Esophageal apical cells: 287.3;Esophageal suprabasal cells: 76.6;Fallopian secretory cells: 31.4;Salivary duct cells: 21.5;Suprabasal keratinocytes: 103.7" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Head and Neck Squamous Cell Carcinoma (TCGA): 129.3;Ovary Serous Cystadenocarcinoma (TCGA): 184.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 80.1" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Skin - Keratinocyte (other)" "Region enriched" "Detected in all" 5 "hippocampal formation: 36.1" "Region enriched" "Detected in single" 4 "basal ganglia: 1.9" "CAB019393, HPA035761" Enhanced Approved Vesicles "Secreted in other tissues" Enzyme NA NA 6900000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 25: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 26: Keratinocytes - Keratinization" 15 Vesicles "CAB019393: , HPA035761: " "potential prognostic unfavorable (1.77e-4)" "unprognostic (6.04e-3)" "unprognostic (2.95e-1)" "unprognostic (5.97e-2)" "unprognostic (9.41e-2)" "unprognostic (1.06e-1)" "unprognostic (4.55e-2)" "unprognostic (1.27e-3)" "unprognostic (1.16e-1)" "unprognostic (1.72e-2)" "unprognostic (7.49e-3)" "unprognostic (9.39e-2)" "unprognostic (1.38e-1)" "potential prognostic unfavorable (8.21e-5)" "unprognostic (4.94e-2)" "unprognostic (1.24e-1)" "unprognostic (2.45e-1)" "unprognostic (1.58e-1)" "unprognostic (4.83e-2)" "unprognostic (1.32e-2)" "unprognostic (9.16e-2)" KLK9 KLK-L3 ENSG00000213022 "Kallikrein related peptidase 9" Q9UKQ9 19 51002508-51009634 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 6.4;esophagus: 5.0;skin 1: 11.3" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Head and Neck Squamous Cell Carcinoma (TCGA): 28.2;Skin Cutaneous Melanoma (TCGA): 10.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 3.1;head and neck cancer: 8.6" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Not detected" "Not detected" CAB025049 Enhanced "Secreted in other tissues" Enzyme NA NA "Cluster 58: Skin - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 98: Neurons - Neurotransmission & signaling" 4 "CAB025049: " "unprognostic (5.87e-3)" "unprognostic (3.64e-1)" "unprognostic (1.82e-1)" "unprognostic (3.31e-2)" "unprognostic (1.85e-1)" KLKB1 KLK3 ENSG00000164344 "Kallikrein B1" P03952 4 186226438-186258471 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis, Inflammatory response" "Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 28 "liver: 306.8" "Cell type enhanced" "Detected in some" "Astrocytes: 99.2;Bergmann glia: 35.6;Brain inhibitory neurons: 17.2;Choroid plexus epithelial cells: 114.7;Distal convoluted tubule cells: 18.8;Ependymal cells: 69.6;Loop of henle epithelial cells: 38.2;Oligodendrocyte progenitor cells: 17.3;Oligodendrocytes: 18.5;Proximal tubule cells: 75.8;Renal collecting duct principal cells: 19.6;Renal connecting tubule cells: 32.6" "Cell type enhanced" "Detected in all" "astrocyte: 107.4" "Cancer enriched" "Detected in some" 14 "Liver Hepatocellular Carcinoma (TCGA): 45.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to blood" "Blood coagulation" NA NA 28900000000 12000000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 23: Choroid plexus - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 28: Astrocytes - Homeostasis & neuron support" 9 "unprognostic (2.68e-2)" "unprognostic (3.20e-1)" "unprognostic (9.13e-2)" "unprognostic (7.11e-3)" "unprognostic (3.86e-2)" "unprognostic (8.81e-3)" "potential prognostic favorable (8.52e-5)" "unprognostic (4.06e-3)" KLLN killin ENSG00000227268 "Killin, p53 regulated DNA replication inhibitor" B2CW77 10 87859158-87863533 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Cell cycle" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skeletal muscle: 4.1" "Cell type enhanced" "Detected in single" "Papillary tip epithelial cells: 1.1" "Cell type enhanced" "Detected in some" "pericyte: 3.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.5" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipocytes (Visceral), Liver - Hepatocytes" HPA074502 Supported Nucleoplasm,Nucleoli No No "Cluster 20: Non-specific - DNA binding" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 98: Neurons - Neurotransmission & signaling" Nucleoplasm Nucleoli "HPA074502: " "unprognostic (4.49e-2)" "unprognostic (8.18e-3)" "unprognostic (5.64e-2)" "unprognostic (2.58e-1)" "unprognostic (1.16e-1)" "unprognostic (2.97e-2)" "unprognostic (2.36e-1)" "unprognostic (2.09e-1)" "unprognostic (2.91e-2)" "unprognostic (5.69e-2)" "unprognostic (1.48e-1)" KLRB1 "CD161, CLEC5B, hNKR-P1A, NKR, NKR-P1, NKR-P1A" ENSG00000111796 "Killer cell lectin like receptor B1" Q12918 12 9594551-9607916 "CD markers, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 44.6;lymphoid tissue: 34.1" "Group enriched" "Detected in many" 34 "Innate lymphoid cells: 955.1;NK-cells: 950.8;T-cells: 643.7" "Cell type enriched" "Detected in many" 25 "leukocyte: 124.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "MAIT T-cell: 2180.9" "Group enriched" "Detected in all" 140 "NK-cells: 758.3;T-cells: 2180.9" "Cancer enhanced" "Detected in single" "Brain cancer: 1.1" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Minor Salivary Gland - T-cells, Pancreas - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Spleen - NK-cells (Spleen), Thyroid gland - T-cells" "Not detected" "Not detected" HPA039113 Approved Uncertain Nucleoplasm,Cytosol NA NA "Cluster 1: T-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 14: Neurons - Synaptic function" "Cluster 72: Neuronal - Signal transduction" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 35 Nucleoplasm Cytosol "HPA039113: " "unprognostic (1.82e-2)" "potential prognostic favorable (8.92e-5)" "unprognostic (1.34e-1)" "potential prognostic favorable (2.67e-4)" "unprognostic (1.54e-1)" "unprognostic (4.37e-2)" "unprognostic (4.89e-2)" "potential prognostic favorable (4.39e-4)" "unprognostic (1.88e-1)" "unprognostic (5.34e-2)" "unprognostic (3.85e-2)" "unprognostic (2.20e-1)" "potential prognostic favorable (3.47e-4)" "unprognostic (6.44e-2)" "unprognostic (1.26e-3)" "unprognostic (2.08e-2)" "unprognostic (3.78e-1)" "unprognostic (2.21e-1)" "unprognostic (7.04e-3)" "unprognostic (3.43e-1)" "unprognostic (2.54e-2)" "unprognostic (7.78e-2)" "unprognostic (2.65e-1)" "unprognostic (2.68e-2)" "unprognostic (1.59e-1)" "unprognostic (2.00e-1)" "unprognostic (5.19e-1)" "unprognostic (1.30e-3)" "unprognostic (8.69e-2)" KLRC1 "CD159a, NKG2, NKG2-A, NKG2-B" ENSG00000134545 "Killer cell lectin like receptor C1" P26715 12 10442264-10454685 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 6.2" "Group enriched" "Detected in some" 4 "NK-cells: 282.6;T-cells: 107.0" "Cell type enriched" "Detected in some" 60 "leukocyte: 107.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "gdT-cell: 229.7;NK-cell: 368.5" "Group enriched" "Detected in many" 47 "NK-cells: 368.5;T-cells: 229.7" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Liver - NK-cells (Liver), Minor Salivary Gland - T-cells, Pancreas - T-cells, Prostate - T-cells, Spleen - NK-cells (Spleen), Stomach - T-cells" HPA058052 Approved "Plasma membrane" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 11: White matter - Signal transduction" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 44 "Plasma membrane" "HPA058052: " "unprognostic (4.00e-2)" "unprognostic (2.80e-1)" "unprognostic (5.81e-2)" "unprognostic (5.44e-3)" "unprognostic (7.23e-2)" "unprognostic (3.31e-3)" "unprognostic (5.21e-3)" "unprognostic (3.31e-3)" "unprognostic (1.84e-1)" "unprognostic (1.03e-1)" "unprognostic (4.05e-1)" "unprognostic (6.17e-3)" "unprognostic (3.03e-1)" "unprognostic (1.47e-1)" "unprognostic (2.38e-1)" "unprognostic (5.03e-2)" "unprognostic (1.04e-1)" "unprognostic (9.46e-2)" "unprognostic (1.53e-1)" "unprognostic (3.88e-1)" KLRC2 "CD159c, NKG2-C, NKG2C" ENSG00000205809 "Killer cell lectin like receptor C2" P26717 12 10426854-10442300 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.0;lymphoid tissue: 5.1" "Cell type enhanced" "Detected in some" "Innate lymphoid cells: 3.0;NK-cells: 30.3;Oligodendrocyte progenitor cells: 49.9;Oligodendrocytes: 3.9;T-cells: 11.5" "Group enriched" "Detected in some" 5 "leukocyte: 49.4;oligodendrocyte precursor cell: 56.1" "Cancer enriched" "Detected in many" 10 "Glioblastoma Multiforme (TCGA): 18.6" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "gdT-cell: 24.7;NK-cell: 84.6" "Group enriched" "Detected in many" 103 "NK-cells: 84.6;T-cells: 24.7" "Cancer enhanced" "Detected in many" "thyroid cancer: 16.2" "Adipose visceral - T-cells, Minor Salivary Gland - T-cells, Prostate - T-cells, Thyroid gland - T-cells" HPA058052 Approved "Plasma membrane" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 73: Brain - Neuronal signaling" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 3 "Plasma membrane" "HPA058052: " "unprognostic (1.42e-1)" "unprognostic (1.81e-1)" "unprognostic (2.27e-3)" "unprognostic (7.21e-2)" "unprognostic (3.94e-1)" "unprognostic (1.63e-1)" "potential prognostic favorable (6.25e-4)" "unprognostic (1.25e-1)" "unprognostic (1.22e-1)" "unprognostic (9.02e-2)" "unprognostic (9.67e-3)" "unprognostic (5.52e-3)" "unprognostic (4.02e-1)" "potential prognostic favorable (8.59e-5)" "unprognostic (1.13e-1)" "unprognostic (2.34e-2)" KLRC3 NKG2-E ENSG00000205810 "Killer cell lectin like receptor C3" Q07444 12 10412315-10420595 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 1.8;brain: 4.7;intestine: 1.2;lymphoid tissue: 3.9" "Cell type enriched" "Detected in some" 4 "Oligodendrocyte progenitor cells: 64.0" "Cell type enhanced" "Detected in some" "leukocyte: 52.4;oligodendrocyte precursor cell: 76.4" "Cancer enriched" "Detected in single" 6 "Glioblastoma Multiforme (TCGA): 4.0" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 6 "NK-cell: 63.5" "Lineage enriched" "Detected in many" 6 "NK-cells: 63.5" "Cancer enhanced" "Detected in some" "lymphoma: 5.2;thyroid cancer: 5.6" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Minor Salivary Gland - T-cells, Prostate - T-cells, Spleen - NK-cells (Spleen), Thyroid gland - T-cells" "HPA039910, HPA062570" Approved Uncertain Vesicles NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 73: Brain - Neuronal signaling" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" Vesicles "HPA039910: , HPA062570: " "unprognostic (3.47e-1)" "unprognostic (8.34e-2)" "potential prognostic favorable (4.36e-4)" "unprognostic (5.42e-2)" KLRC4 NKG2-F ENSG00000183542 "Killer cell lectin like receptor C4" O43908 12 10407384-10409757 "Predicted membrane proteins, Transporters" Receptor "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 8.9" "Cell type enhanced" "Detected in some" "NK-cells: 3.9;Oligodendrocyte progenitor cells: 14.6;Oligodendrocytes: 1.6;T-cells: 3.1" "Cell type enriched" "Detected in some" 5 "leukocyte: 82.9" "Cancer enhanced" "Detected in single" "Glioblastoma Multiforme (TCGA): 1.7" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 20 "gdT-cell: 8.2;memory CD8 T-cell: 5.9;naive CD8 T-cell: 6.8;NK-cell: 4.8" "Group enriched" "Detected in many" 59 "NK-cells: 4.8;T-cells: 8.2" "Cancer enhanced" "Detected in some" "lymphoma: 6.1;thyroid cancer: 3.6" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Colon - T-cells, Kidney - T-cells, Minor Salivary Gland - T-cells, Prostate - T-cells, Spleen - NK-cells (Spleen), Stomach - T-cells, Testis - Early spermatids, Thyroid gland - T-cells" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 102: Non-specific - Mixed function" 2 "unprognostic (2.73e-1)" "unprognostic (1.11e-1)" "unprognostic (3.35e-2)" "potential prognostic favorable (9.14e-4)" "unprognostic (6.12e-2)" "unprognostic (1.79e-1)" "unprognostic (3.24e-2)" "unprognostic (2.57e-1)" KLRD1 CD94 ENSG00000134539 "Killer cell lectin like receptor D1" Q13241 12 10226058-10329608 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 16.2" "Group enriched" "Detected in many" 4 "NK-cells: 1052.7;T-cells: 298.0" "Cell type enhanced" "Detected in all" "leukocyte: 344.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "gdT-cell: 513.3;memory CD8 T-cell: 218.1;naive CD8 T-cell: 219.5;NK-cell: 737.5" "Group enriched" "Detected in many" 66 "NK-cells: 737.5;T-cells: 513.3" "Low cancer specificity" "Detected in many" "Adipose visceral - T-cells, Adrenal gland - T-cells, Heart muscle - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Minor Salivary Gland - T-cells, Pituitary gland - Somatotropes, Prostate - T-cells, Spleen - NK-cells (Spleen), Stomach - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA069688 Uncertain NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 9: Non-specific - Receptor signaling" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 6 "HPA069688: " "unprognostic (7.07e-2)" "unprognostic (3.68e-2)" "unprognostic (2.37e-1)" "unprognostic (7.12e-2)" "unprognostic (1.64e-1)" "unprognostic (2.44e-1)" "unprognostic (3.61e-3)" "unprognostic (2.25e-1)" "unprognostic (2.82e-1)" "unprognostic (7.01e-2)" "unprognostic (2.19e-2)" "unprognostic (1.01e-1)" "unprognostic (1.97e-2)" "unprognostic (8.56e-2)" "unprognostic (1.79e-1)" "unprognostic (4.51e-2)" "unprognostic (6.30e-2)" "unprognostic (2.87e-3)" "unprognostic (3.24e-1)" "unprognostic (8.45e-2)" "unprognostic (9.80e-3)" "unprognostic (1.96e-1)" "unprognostic (3.34e-1)" "unprognostic (3.06e-1)" "unprognostic (5.14e-2)" "unprognostic (1.06e-2)" KLRF1 "CLEC5C, NKp80" ENSG00000150045 "Killer cell lectin like receptor F1" Q9NZS2 12 9827481-9845007 "Predicted membrane proteins" "Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 12.0;lymphoid tissue: 17.0" "Cell type enriched" "Detected in many" 15 "NK-cells: 512.1" "Cell type enriched" "Detected in some" 19 "leukocyte: 194.9" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 7 "NK-cell: 665.9" "Lineage enriched" "Detected in all" 7 "NK-cells: 665.9" "Not detected" "Not detected" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Spleen - NK-cells (Spleen)" "Low region specificity" "Detected in many" HPA054038 Approved "Plasma membrane" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" "Plasma membrane" "HPA054038: " "unprognostic (3.36e-2)" "unprognostic (1.35e-1)" "unprognostic (1.21e-1)" "unprognostic (3.38e-1)" "potential prognostic favorable (2.25e-6)" "unprognostic (2.64e-1)" "unprognostic (8.39e-2)" "unprognostic (2.44e-2)" "unprognostic (1.16e-1)" "unprognostic (3.66e-1)" "unprognostic (2.78e-1)" "unprognostic (8.04e-2)" KLRF2 NKp65 ENSG00000256797 "Killer cell lectin like receptor F2" D3W0D1 12 9881489-9895833 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 13 "skin 1: 11.2" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 2.2;Innate lymphoid cells: 9.8;NK-cells: 14.1;Parietal cells: 1.8;pDCs: 4.6;Suprabasal keratinocytes: 2.7;T-cells: 1.9;Thymocytes: 4.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 32 "NK-cell: 3.1;plasmacytoid DC: 3.2" "Group enriched" "Detected in many" 32 "dendritic cells: 3.2;NK-cells: 3.1" "Group enriched" "Detected in some" 26 "Leukemia: 4.1;lymphoma: 1.3;Myeloma: 5.2" "Skin - Keratinocyte (other)" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 37: Skin - Keratinization" "Cluster 59: Leukemia - T-cell receptor" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 1 KLRG1 "2F1, CLEC15A, MAFA, MAFA-L" ENSG00000139187 "Killer cell lectin like receptor G1" Q96E93 12 8950044-9010760 "Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 9.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 45.4;Mast cells: 135.4;Myonuclei: 56.6;NK-cells: 72.4;T-cells: 98.3" "Cell type enhanced" "Detected in all" "leukocyte: 109.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "gdT-cell: 391.8;MAIT T-cell: 462.2" "Lineage enriched" "Detected in all" 22 "T-cells: 462.2" "Low cancer specificity" "Detected in many" "Prostate - Fibroblasts, Spleen - T-cells, Stomach - Fibroblasts, Thyroid gland - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA051403, HPA076494" Approved Enhanced Vesicles NA NA "Cluster 1: T-cells - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 9 Vesicles "HPA051403: , HPA076494: " "unprognostic (1.71e-1)" "unprognostic (8.72e-2)" "unprognostic (1.54e-2)" "unprognostic (1.98e-2)" "unprognostic (1.85e-1)" "unprognostic (6.42e-3)" "unprognostic (5.37e-2)" "unprognostic (2.42e-1)" "unprognostic (1.81e-1)" "unprognostic (1.57e-1)" "potential prognostic favorable (1.30e-5)" "unprognostic (1.20e-1)" "unprognostic (2.57e-1)" "unprognostic (1.58e-1)" "unprognostic (8.78e-2)" "unprognostic (5.07e-1)" "unprognostic (3.02e-3)" "unprognostic (6.36e-2)" "unprognostic (5.97e-2)" "unprognostic (5.75e-3)" "unprognostic (1.39e-1)" "unprognostic (2.22e-1)" "unprognostic (1.03e-1)" "unprognostic (1.72e-2)" KLRG2 "CLEC15B, FLJ44186" ENSG00000188883 "Killer cell lectin like receptor G2" A4D1S0 7 139452690-139483673 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 3.7;kidney: 4.7;salivary gland: 4.1;thyroid gland: 3.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 30.4;Esophageal basal cells: 19.0;Esophageal suprabasal cells: 13.2;Loop of henle epithelial cells: 109.4;Proximal tubule cells: 33.1;Renal collecting duct principal cells: 35.4;Thyrotrophs: 12.0" "Group enriched" "Detected in some" 7 "fibroblast: 9.6;hippocampal CA1-3: 3.3" "Cancer enriched" "Detected in many" 8 "Testicular Germ Cell Tumor (TCGA): 60.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 11.8" "Breast - Breast glandular cells (progenitors), Kidney - Fibroblasts, Lung - Alveolar cells type 1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA018199 Uncertain Uncertain Nucleoplasm NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 6: Non-specific - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" Nucleoplasm "HPA018199: " "unprognostic (2.34e-2)" "unprognostic (1.15e-2)" "unprognostic (2.19e-1)" "unprognostic (1.24e-2)" "unprognostic (4.07e-2)" "unprognostic (2.04e-1)" "unprognostic (8.18e-3)" "potential prognostic favorable (5.17e-4)" "unprognostic (3.17e-2)" "unprognostic (2.53e-3)" "unprognostic (4.91e-2)" "unprognostic (2.43e-1)" "unprognostic (3.89e-2)" "unprognostic (2.18e-1)" "unprognostic (2.74e-3)" "unprognostic (1.03e-2)" KLRK1 "CD314, D12S2489E, KLR, NKG2-D, NKG2D" ENSG00000213809 "Killer cell lectin like receptor K1" P26718 12 10372353-10391874 "Cancer-related genes, CD markers, Predicted membrane proteins, Transporters" "Adaptive immunity, Differentiation, Immunity, Innate immunity" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.8;lymphoid tissue: 39.4" "Group enriched" "Detected in some" 12 "NK-cells: 22.5;Oligodendrocyte progenitor cells: 25.1;Oligodendrocytes: 8.3;T-cells: 12.0" "Cell type enriched" "Detected in some" 11 "leukocyte: 279.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 40 "gdT-cell: 287.0;MAIT T-cell: 111.2;memory CD8 T-cell: 260.3;naive CD8 T-cell: 258.6;NK-cell: 335.6" "Group enriched" "Detected in all" 49 "NK-cells: 335.6;T-cells: 287.0" "Group enriched" "Detected in some" 15 "Leukemia: 9.9;lymphoma: 31.2" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - NK-cells (Liver), Minor Salivary Gland - T-cells, Pancreas - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Stomach - T-cells, Testis - Early spermatids, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB021896, HPA068877" Enhanced Supported "Plasma membrane" NA NA 41000 "Cluster 1: T-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 102: Non-specific - Mixed function" 5 "Plasma membrane" "CAB021896: , HPA068877: " "unprognostic (4.38e-2)" "potential prognostic favorable (2.53e-4)" "unprognostic (6.76e-3)" "unprognostic (2.28e-3)" "unprognostic (8.77e-2)" "unprognostic (1.17e-1)" "unprognostic (4.78e-2)" "unprognostic (1.87e-3)" "unprognostic (4.21e-3)" "unprognostic (2.92e-1)" "unprognostic (1.39e-2)" "unprognostic (3.41e-1)" "potential prognostic unfavorable (9.13e-4)" "unprognostic (5.88e-3)" "unprognostic (1.87e-3)" "unprognostic (2.92e-2)" "unprognostic (2.23e-1)" "unprognostic (4.23e-2)" "unprognostic (2.57e-2)" "unprognostic (4.22e-2)" "unprognostic (9.51e-3)" "unprognostic (9.90e-2)" "unprognostic (3.06e-3)" "unprognostic (3.34e-1)" "unprognostic (1.75e-1)" "unprognostic (6.80e-2)" "unprognostic (1.94e-2)" "unprognostic (2.37e-1)" "unprognostic (2.90e-2)" "unprognostic (5.00e-3)" "unprognostic (1.50e-1)" KMO ENSG00000117009 "Kynurenine 3-monooxygenase" O15229 1 241532134-241595642 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Pyridine nucleotide biosynthesis" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 29.3;liver: 85.6" "Cell type enhanced" "Detected in many" "B-cells: 65.5;cDC: 126.8;Endometrial glandular cells: 144.5;Hepatocytes: 108.3;Kupffer cells: 191.7;Macrophages: 203.4;monocytes: 288.9;pDCs: 64.6;Salivary ionocytes: 66.9;Syncytiotrophoblasts: 453.2" "Cell type enriched" "Detected in many" 4 "CGE interneuron: 71.0" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 17.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 100 "classical monocyte: 11.1;intermediate monocyte: 32.3;memory B-cell: 36.2;myeloid DC: 11.3;naive B-cell: 42.2;non-classical monocyte: 34.0;plasmacytoid DC: 24.4" "Group enriched" "Detected in many" 122 "B-cells: 42.2;dendritic cells: 24.4;monocytes: 34.0" "Cancer enhanced" "Detected in many" "Bone cancer: 26.3" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Kidney - Proximal tubular cells, Lung - Macrophages, Spleen - B-cells (Spleen), Testis - Early spermatids" "Region enriched" "Detected in single" 4 "thalamus: 1.1" "Low region specificity" "Detected in many" "HPA031115, HPA056942" Enhanced NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 53: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" "HPA031115: , HPA056942: " "unprognostic (1.80e-2)" "unprognostic (7.84e-3)" "unprognostic (1.75e-1)" "unprognostic (4.45e-3)" "unprognostic (5.12e-2)" "potential prognostic unfavorable (9.47e-4)" "unprognostic (1.05e-2)" "unprognostic (1.80e-1)" "unprognostic (1.99e-1)" "unprognostic (6.53e-3)" "unprognostic (1.18e-1)" "unprognostic (1.91e-1)" "unprognostic (1.37e-1)" "unprognostic (2.72e-3)" "unprognostic (7.49e-2)" "unprognostic (1.29e-1)" "unprognostic (3.62e-2)" "unprognostic (2.08e-1)" "unprognostic (1.15e-2)" "unprognostic (2.46e-1)" "unprognostic (8.36e-3)" "unprognostic (2.36e-1)" "unprognostic (4.30e-1)" "unprognostic (2.72e-1)" "unprognostic (9.31e-2)" "unprognostic (5.05e-2)" "unprognostic (4.58e-1)" KMT2A "ALL-1, ALL1, CXXC7, HRX, HTRX, HTRX1, MLL, MLL1, MLL1A, TRX1" ENSG00000118058 "Lysine methyltransferase 2A" Q03164 11 118436456-118526832 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Apoptosis, Biological rhythms, Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017794, CAB024270, HPA044910" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 16: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 102: Non-specific - Mixed function" 111 Nucleoplasm Cytosol "CAB017794: , CAB024270: , HPA044910: " "unprognostic (4.14e-2)" "unprognostic (6.50e-2)" "unprognostic (2.12e-2)" "unprognostic (2.79e-1)" "unprognostic (1.30e-2)" "unprognostic (3.60e-2)" "unprognostic (1.95e-3)" "unprognostic (1.67e-2)" "unprognostic (1.78e-2)" "validated prognostic favorable (2.17e-5)" "validated prognostic favorable (1.46e-4)" "unprognostic (1.10e-1)" "unprognostic (2.45e-2)" "unprognostic (4.63e-1)" "unprognostic (1.14e-2)" "unprognostic (3.90e-2)" "unprognostic (2.35e-1)" "unprognostic (2.85e-2)" "unprognostic (1.83e-1)" "unprognostic (3.07e-1)" "unprognostic (1.03e-2)" "unprognostic (3.08e-1)" "unprognostic (2.74e-3)" "unprognostic (5.57e-3)" "unprognostic (2.51e-1)" "unprognostic (7.33e-2)" "unprognostic (3.06e-1)" "unprognostic (4.48e-2)" "unprognostic (3.83e-1)" KMT2B "CXXC10, HRX2, KIAA0304, MLL1B, MLL2, MLL4, TRX2, WBP7" ENSG00000272333 "Lysine methyltransferase 2B" Q9UMN6 19 35717973-35738880 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Disease variant, Dystonia, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006487 Approved Nucleoplasm,Cytosol NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 39: Testis - Nuclear processes" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 4: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 17 Nucleoplasm Cytosol "HPA006487: " "unprognostic (3.64e-1)" "unprognostic (1.49e-2)" "unprognostic (2.20e-1)" "unprognostic (6.88e-2)" "unprognostic (4.14e-2)" "unprognostic (1.78e-1)" "unprognostic (7.76e-2)" "unprognostic (3.48e-1)" "potential prognostic unfavorable (8.15e-6)" "unprognostic (1.60e-1)" "unprognostic (1.65e-1)" "unprognostic (4.17e-3)" "unprognostic (2.61e-2)" "unprognostic (2.50e-2)" "unprognostic (1.10e-1)" "unprognostic (3.13e-2)" "unprognostic (7.89e-2)" "unprognostic (3.65e-3)" "unprognostic (4.42e-2)" "unprognostic (3.84e-2)" "unprognostic (8.07e-2)" "unprognostic (1.80e-1)" "unprognostic (2.87e-2)" "unprognostic (2.63e-1)" "unprognostic (1.94e-1)" "unprognostic (1.06e-1)" KMT2C "HALR, KIAA1506, MLL3" ENSG00000055609 "Lysine methyltransferase 2C" Q8NEZ4 7 152134922-152436644 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Acyltransferase, Chromatin regulator, DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 1797.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062814, HPA074736" Enhanced Nucleoplasm,Cytosol NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 39: Non-specific - Transcription" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 34 Nucleoplasm Cytosol "HPA062814: , HPA074736: " "unprognostic (4.41e-2)" "unprognostic (5.97e-2)" "unprognostic (1.74e-1)" "unprognostic (9.00e-2)" "unprognostic (5.25e-2)" "unprognostic (2.91e-1)" "unprognostic (1.01e-1)" "unprognostic (9.48e-3)" "unprognostic (7.98e-2)" "potential prognostic favorable (1.62e-6)" "unprognostic (2.75e-3)" "unprognostic (2.35e-1)" "unprognostic (1.89e-1)" "unprognostic (1.69e-2)" "unprognostic (2.04e-1)" "unprognostic (1.45e-1)" "unprognostic (1.30e-1)" "unprognostic (1.95e-1)" "unprognostic (2.32e-1)" "unprognostic (1.72e-1)" "unprognostic (4.90e-2)" "unprognostic (2.75e-1)" "unprognostic (3.22e-2)" "unprognostic (1.77e-2)" "unprognostic (9.91e-2)" "unprognostic (2.35e-1)" "unprognostic (3.67e-1)" "unprognostic (9.95e-3)" "unprognostic (9.79e-2)" KMT2D "ALR, CAGL114, MLL2, MLL4, TNRC21" ENSG00000167548 "Lysine methyltransferase 2D" O14686 12 49018975-49060794 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Transferase" "Cancer-related genes, Congenital hypothyroidism, Deafness, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 88.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035977 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" Yes No "Cluster 2: Dendritic cells - Unknown function" "Cluster 40: Non-specific - Mixed function" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 39 "Plasma membrane, Cytosol" Nucleoplasm "HPA035977: " "unprognostic (5.28e-2)" "unprognostic (1.03e-1)" "unprognostic (7.45e-3)" "unprognostic (6.54e-2)" "unprognostic (1.11e-1)" "unprognostic (7.03e-2)" "unprognostic (1.78e-1)" "unprognostic (1.34e-1)" "unprognostic (7.31e-2)" "unprognostic (1.77e-2)" "unprognostic (1.96e-2)" "unprognostic (7.98e-2)" "unprognostic (8.26e-3)" "unprognostic (1.86e-1)" "unprognostic (3.03e-1)" "unprognostic (1.35e-1)" "unprognostic (3.81e-3)" "unprognostic (9.90e-2)" "unprognostic (1.79e-1)" "unprognostic (3.29e-2)" "unprognostic (2.21e-2)" "unprognostic (4.77e-3)" "unprognostic (1.56e-1)" "unprognostic (8.17e-3)" "unprognostic (1.61e-1)" "unprognostic (2.27e-1)" "unprognostic (9.95e-2)" "unprognostic (7.85e-2)" "unprognostic (1.26e-1)" KMT2E "HDCMC04P, MLL5, SETD5B" ENSG00000005483 "Lysine methyltransferase 2E (inactive)" Q8IZD2 7 104940943-105115019 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Growth arrest, Transcription, Transcription regulation" "Chromatin regulator" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 1496.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pancreas - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042866, HPA056125" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 40: Non-specific - Mixed function" "Cluster 16: Non-specific - Transcription" "Cluster 39: Non-specific - Transcription" "Cluster 103: Non-specific - Basic cellular processes" 5 Nucleoplasm "Nuclear bodies, Cytosol" "HPA042866: , HPA056125: " "potential prognostic favorable (7.96e-4)" "unprognostic (2.13e-1)" "unprognostic (8.44e-3)" "unprognostic (1.00e-1)" "unprognostic (1.19e-2)" "unprognostic (2.94e-1)" "unprognostic (1.17e-1)" "unprognostic (8.17e-2)" "unprognostic (3.50e-3)" "validated prognostic favorable (3.55e-5)" "validated prognostic favorable (5.22e-4)" "unprognostic (3.73e-2)" "unprognostic (8.57e-2)" "unprognostic (6.64e-2)" "unprognostic (9.94e-2)" "unprognostic (1.41e-2)" "unprognostic (1.07e-1)" "unprognostic (1.78e-3)" "unprognostic (1.69e-1)" "unprognostic (2.16e-2)" "unprognostic (2.53e-2)" "unprognostic (1.36e-1)" "unprognostic (1.97e-1)" "unprognostic (1.38e-2)" "unprognostic (2.48e-2)" "unprognostic (1.00e-1)" "unprognostic (1.67e-1)" "unprognostic (3.19e-2)" "unprognostic (1.74e-1)" KMT5A "PR-Set7, SET07, SET8, SETD8" ENSG00000183955 "Lysine methyltransferase 5A" Q9NQR1 12 123384132-123409353 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 136.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064495 Supported Nucleoplasm,Cytosol NA Yes "Cluster 32: Basophils - Transcription" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 6: Non-specific - Immune response" "Cluster 38: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 33 Nucleoplasm Cytosol "HPA064495: " "unprognostic (1.52e-2)" "unprognostic (1.84e-1)" "unprognostic (2.10e-2)" "unprognostic (2.58e-1)" "unprognostic (1.40e-3)" "unprognostic (1.03e-1)" "unprognostic (2.25e-1)" "unprognostic (2.08e-1)" "unprognostic (1.27e-1)" "unprognostic (2.77e-3)" "unprognostic (1.33e-2)" "unprognostic (5.60e-2)" "potential prognostic unfavorable (1.99e-8)" "potential prognostic unfavorable (6.56e-4)" "unprognostic (1.69e-2)" "unprognostic (2.20e-2)" "unprognostic (5.97e-2)" "unprognostic (2.84e-2)" "unprognostic (2.17e-2)" "unprognostic (8.50e-2)" "unprognostic (2.68e-2)" "unprognostic (3.65e-1)" "unprognostic (2.00e-1)" "unprognostic (2.00e-2)" "unprognostic (6.01e-2)" "unprognostic (1.30e-1)" "unprognostic (1.60e-1)" "unprognostic (4.40e-2)" "unprognostic (9.21e-2)" KMT5B "CGI-85, SUV420H1" ENSG00000110066 "Lysine methyltransferase 5B" Q4FZB7 11 68154863-68213852 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Myogenesis, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pancreas - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038509 Supported "Nucleoplasm,Nucleoli fibrillar center,Plasma membrane,Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Centrosome,Basal body,Cytoplasmic bodies" Yes NA "Cluster 45: Eosinophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 4 "Nucleoplasm, Nucleoli fibrillar center" "Plasma membrane, Microtubules, Cytokinetic bridge, Mitotic spindle, Primary cilium, Centrosome, Basal body, Cytoplasmic bodies" "HPA038509: " "unprognostic (1.14e-1)" "unprognostic (3.70e-2)" "unprognostic (2.36e-3)" "unprognostic (2.27e-1)" "unprognostic (6.98e-3)" "unprognostic (4.75e-1)" "unprognostic (1.20e-2)" "unprognostic (6.20e-2)" "unprognostic (2.31e-1)" "potential prognostic favorable (3.27e-4)" "unprognostic (2.69e-3)" "unprognostic (1.12e-1)" "potential prognostic unfavorable (8.79e-4)" "unprognostic (2.13e-2)" "unprognostic (2.00e-3)" "unprognostic (5.41e-2)" "unprognostic (3.73e-1)" "unprognostic (2.65e-1)" "unprognostic (1.31e-2)" "unprognostic (6.81e-3)" "potential prognostic unfavorable (6.17e-4)" "unprognostic (3.88e-2)" "unprognostic (7.03e-2)" "unprognostic (5.54e-2)" "unprognostic (1.65e-1)" "unprognostic (4.02e-1)" "unprognostic (4.20e-1)" "unprognostic (1.38e-1)" "unprognostic (1.10e-1)" KMT5C "MGC2705, SUV420H2" ENSG00000133247 "Lysine methyltransferase 5C" Q86Y97 19 55339853-55348121 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Migrating cytotrophoblasts: 48.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052294, HPA075095" Uncertain Enhanced Nucleoplasm NA NA "Cluster 64: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 4: Non-specific - Transcription" "Cluster 65: Non-specific - Cell growth & division" 5 Nucleoplasm "HPA052294: , HPA075095: " "unprognostic (5.49e-2)" "unprognostic (1.10e-1)" "unprognostic (1.42e-2)" "unprognostic (8.72e-2)" "unprognostic (2.08e-1)" "unprognostic (1.76e-1)" "unprognostic (6.42e-2)" "unprognostic (3.63e-2)" "unprognostic (5.67e-2)" "potential prognostic unfavorable (1.51e-12)" "unprognostic (7.65e-2)" "unprognostic (1.64e-2)" "unprognostic (1.33e-2)" "unprognostic (1.77e-1)" "unprognostic (2.30e-1)" "unprognostic (8.75e-2)" "unprognostic (3.36e-2)" "unprognostic (3.21e-1)" "unprognostic (8.66e-3)" "unprognostic (9.12e-3)" "unprognostic (9.46e-2)" "unprognostic (6.11e-2)" "unprognostic (2.52e-1)" "unprognostic (1.61e-1)" "unprognostic (1.77e-1)" "unprognostic (7.47e-2)" "unprognostic (1.60e-1)" "unprognostic (3.18e-1)" "unprognostic (3.74e-1)" KNCN "FLJ32011, KINO, L5" ENSG00000162456 Kinocilin A6PVL3 1 46545641-46551647 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "brain: 1.0" "Group enriched" "Detected in some" 4 "Early spermatids: 14.7;Late spermatids: 53.9" "Cell type enhanced" "Detected in some" "ependymal cell: 7.1;mammillary body: 5.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adrenal gland - Adrenal medulla cells, Pituitary gland - Thyrotropes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 27: Breast cancer - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" KNDC1 "bB439H18.3, C10orf23, FLJ25027, KIAA1768, RASGEF2, v-KIND, Very-KIND" ENSG00000171798 "Kinase non-catalytic C-lobe domain containing 1" Q76NI1 10 133160219-133226412 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 42.0;pituitary gland: 23.9" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 77.1;Astrocytes: 162.3;Brain excitatory neurons: 69.7;Corticotrophs: 124.6;Ependymal cells: 188.2;Epicardial cells: 77.3;Fallopian tube ciliated cells: 85.3;Gonadotrophs: 135.1;Lactotrophs: 80.1;Respiratory ciliated cells: 109.0;Somatotrophs: 147.7;Thyrotrophs: 93.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" "HPA039624, HPA056143" Uncertain Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 27: Cerebellum - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 28: Astrocytes - Homeostasis & neuron support" "Plasma membrane, Cytosol" Vesicles "HPA039624: , HPA056143: " "unprognostic (3.12e-3)" "unprognostic (2.47e-2)" "unprognostic (1.19e-1)" "unprognostic (5.86e-2)" "unprognostic (5.98e-2)" "unprognostic (2.11e-1)" "unprognostic (1.69e-1)" "unprognostic (4.31e-2)" "unprognostic (8.53e-2)" "potential prognostic favorable (9.68e-4)" "unprognostic (2.13e-3)" "unprognostic (1.58e-1)" "unprognostic (3.57e-1)" "unprognostic (8.56e-2)" KNG1 "BDK, BK, HK, HMWK, KNG" ENSG00000113889 "Kininogen 1" P01042 3 186717348-186744410 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis, Inflammatory response" "Protease inhibitor, Thiol protease inhibitor, Vasoactive, Vasodilator" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "liver: 2986.1" "Group enriched" "Detected in some" 10 "Distal convoluted tubule cells: 648.3;Hepatocytes: 2200.9" "Cell type enhanced" "Detected in single" "oligodendrocyte precursor cell: 1.2" "Cancer enriched" "Detected in some" 21 "Liver Hepatocellular Carcinoma (TCGA): 1355.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "Gastric cancer: 4.6;liver cancer: 8.0" "Kidney - Ascending Loop of Henle cells, Liver - Hepatocytes, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA001616, HPA001645, CAB009809" Enhanced "Secreted to blood" "Blood coagulation" NA NA 90000000000 49000000000 "Cluster 16: Liver & Kidney - Metabolism" "Cluster 53: Neurons - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 93: Hepatocytes - Bile production & excretion" 2 "CAB009809: , HPA001616: , HPA001645: " "unprognostic (1.02e-1)" "unprognostic (7.65e-2)" "unprognostic (3.40e-1)" "unprognostic (2.78e-3)" "validated prognostic favorable (7.27e-8)" "validated prognostic favorable (2.75e-4)" "unprognostic (1.63e-1)" KNL1 "AF15Q14, CASC5, CT29, D40, hKNL-1, hSpc105, KIAA1570, MCPH4, PPP1R55, Spc7" ENSG00000137812 "Kinetochore scaffold 1" Q8NG31 15 40594020-40664342 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Cancer-related genes, Disease variant, Intellectual disability, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 4.9;lymphoid tissue: 6.9;testis: 15.8" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 203.3;Early primary spermatocytes: 498.2;Erythrocyte progenitors: 141.6;Late primary spermatocytes: 92.9;Megakaryocyte progenitors: 120.0;Monocyte progenitors: 210.6;Neutrophil progenitors: 124.9;Undifferentiated spermatogonia: 87.6" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 7.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA026624, HPA049647" Enhanced Supported "Nucleoplasm,Nuclear bodies" Yes Yes "Cluster 39: Testis - Nuclear processes" "Cluster 48: Non-specific - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 27: Non-specific - Cell proliferation" 30 Nucleoplasm "Nuclear bodies" "HPA026624: , HPA049647: " "unprognostic (2.31e-2)" "unprognostic (8.58e-2)" "unprognostic (2.45e-2)" "unprognostic (3.27e-1)" "unprognostic (2.55e-1)" "unprognostic (8.79e-3)" "unprognostic (2.78e-2)" "validated prognostic unfavorable (1.94e-4)" "validated prognostic unfavorable (1.86e-4)" "unprognostic (1.06e-1)" "unprognostic (8.52e-2)" "unprognostic (2.30e-1)" "unprognostic (1.60e-2)" "unprognostic (4.11e-3)" "unprognostic (1.17e-1)" "unprognostic (3.57e-1)" "unprognostic (4.94e-2)" "unprognostic (4.80e-1)" "unprognostic (1.59e-1)" KNOP1 "101F10.1, C16orf88, FAM191A, TSG118" ENSG00000103550 "Lysine rich nucleolar protein 1" Q1ED39 16 19701937-19718235 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 164.9;Oligodendrocytes: 188.5" "Cell type enhanced" "Detected in all" "oligodendrocyte: 241.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041079, HPA066169" Uncertain Enhanced "Nucleoli,Nucleoli rim,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 54: Non-specific - Transcription" "Cluster 28: Astrocytes - Homeostasis & neuron support" 57 "Nucleoli, Nucleoli rim" Cytosol "HPA041079: , HPA066169: " "unprognostic (6.28e-2)" "unprognostic (8.52e-3)" "unprognostic (7.38e-2)" "unprognostic (2.11e-1)" "unprognostic (1.51e-1)" "unprognostic (1.04e-1)" "unprognostic (1.14e-3)" "unprognostic (1.02e-1)" "unprognostic (2.94e-3)" "unprognostic (1.10e-1)" "unprognostic (1.72e-1)" "unprognostic (2.19e-1)" "potential prognostic unfavorable (1.62e-7)" "unprognostic (1.64e-3)" "unprognostic (3.81e-3)" "unprognostic (9.67e-2)" "unprognostic (9.14e-2)" "unprognostic (1.62e-1)" "unprognostic (1.26e-2)" "unprognostic (1.64e-2)" "unprognostic (8.28e-3)" "unprognostic (2.67e-2)" "unprognostic (1.97e-3)" "unprognostic (9.44e-2)" "unprognostic (1.99e-3)" "unprognostic (2.74e-1)" "unprognostic (3.10e-1)" "unprognostic (1.31e-3)" "unprognostic (2.07e-3)" KNSTRN "C15orf23, FLJ14502, kinastrin, SKAP, TRAF4AF1" ENSG00000128944 "Kinetochore localized astrin (SPAG5) binding protein" Q9Y448 15 40382721-40394288 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 59.0;thyroid gland: 51.2" "Group enriched" "Detected in many" 11 "Early spermatids: 405.3;Late primary spermatocytes: 260.5;Late spermatids: 939.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Mitotic cells (Spleen), Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA042027 Enhanced Enhanced "Plasma membrane,Mitotic spindle,Centriolar satellite" Yes Yes "Cluster 40: Monocytes - Innate immune response" "Cluster 39: Testis - Nuclear processes" "Cluster 34: Non-specific - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 27: Non-specific - Cell proliferation" 40 "Mitotic spindle, Centriolar satellite" "Plasma membrane" "HPA042027: " "unprognostic (2.57e-3)" "unprognostic (8.13e-3)" "unprognostic (6.90e-2)" "unprognostic (1.94e-1)" "unprognostic (1.87e-1)" "unprognostic (6.45e-2)" "unprognostic (1.07e-2)" "unprognostic (3.58e-2)" "potential prognostic unfavorable (6.23e-4)" "unprognostic (1.47e-3)" "potential prognostic unfavorable (4.79e-4)" "unprognostic (1.35e-3)" "potential prognostic unfavorable (1.88e-4)" "validated prognostic unfavorable (2.28e-7)" "validated prognostic unfavorable (6.92e-4)" "unprognostic (4.11e-2)" "unprognostic (2.39e-2)" "unprognostic (1.09e-1)" "unprognostic (2.38e-2)" "validated prognostic unfavorable (7.28e-6)" "validated prognostic unfavorable (4.08e-4)" "unprognostic (1.40e-1)" "unprognostic (6.59e-2)" "unprognostic (1.13e-1)" "unprognostic (5.40e-3)" "unprognostic (4.10e-1)" "unprognostic (2.97e-1)" "unprognostic (2.36e-1)" "unprognostic (3.55e-2)" KNTC1 "KIAA0166, ROD" ENSG00000184445 "Kinetochore associated 1" P50748 12 122527246-122626396 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 39.7" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 78.4;Early primary spermatocytes: 95.5;Erythrocyte progenitors: 105.1;Megakaryocyte progenitors: 74.4;Megakaryocyte-Erythroid progenitors: 53.9;Monocyte progenitors: 102.4;Neutrophil progenitors: 72.1;Plasma cells: 73.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA025241 Approved Supported "Plasma membrane,Cytosol" NA Yes "Cluster 32: Basophils - Transcription" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 48: Non-specific - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 27: Non-specific - Cell proliferation" 13 Cytosol "Plasma membrane" "HPA025241: " "unprognostic (4.27e-1)" "unprognostic (1.19e-1)" "unprognostic (4.61e-2)" "unprognostic (4.67e-3)" "unprognostic (1.31e-1)" "unprognostic (3.67e-2)" "unprognostic (1.96e-1)" "unprognostic (6.37e-2)" "unprognostic (3.17e-3)" "unprognostic (1.73e-1)" "validated prognostic unfavorable (2.33e-9)" "validated prognostic unfavorable (1.37e-7)" "unprognostic (3.21e-2)" "potential prognostic unfavorable (1.08e-4)" "unprognostic (3.11e-3)" "unprognostic (4.33e-3)" "potential prognostic unfavorable (7.82e-4)" "unprognostic (8.36e-3)" "unprognostic (4.37e-3)" "unprognostic (1.12e-1)" "unprognostic (5.80e-2)" "unprognostic (1.13e-1)" "potential prognostic unfavorable (6.40e-4)" "unprognostic (1.01e-1)" "unprognostic (4.54e-2)" "unprognostic (2.30e-2)" "unprognostic (2.92e-3)" "unprognostic (4.70e-2)" "unprognostic (3.12e-1)" "unprognostic (9.76e-2)" "unprognostic (4.93e-2)" KPNA1 "IPOA5, NPI-1, RCH2, SRP1" ENSG00000114030 "Karyopherin subunit alpha 1" P52294 3 122421902-122514945 "Predicted intracellular proteins, Transporters" "Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 418.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053627, HPA063426" Supported Enhanced Nucleoplasm,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 63: Non-specific - Protein processing" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 158 Nucleoplasm Cytosol "HPA053627: , HPA063426: " "unprognostic (3.04e-1)" "unprognostic (1.07e-2)" "unprognostic (1.15e-1)" "unprognostic (9.33e-2)" "unprognostic (3.79e-2)" "unprognostic (7.63e-2)" "unprognostic (1.36e-1)" "unprognostic (1.96e-1)" "unprognostic (2.61e-1)" "unprognostic (1.42e-2)" "potential prognostic favorable (1.44e-5)" "unprognostic (3.30e-1)" "unprognostic (2.40e-1)" "unprognostic (1.72e-1)" "unprognostic (1.29e-1)" "potential prognostic unfavorable (8.32e-4)" "unprognostic (6.25e-2)" "unprognostic (2.07e-1)" "unprognostic (1.81e-1)" "unprognostic (4.07e-3)" "potential prognostic unfavorable (6.78e-4)" "unprognostic (1.61e-2)" "unprognostic (1.56e-2)" "unprognostic (2.15e-1)" "unprognostic (2.06e-1)" "unprognostic (4.19e-2)" "unprognostic (8.28e-2)" "unprognostic (3.20e-1)" "unprognostic (1.84e-1)" "unprognostic (1.81e-1)" "unprognostic (1.14e-2)" KPNA2 "IPOA1, PTAC58, QIP2, RCH1, SRP1alpha" ENSG00000182481 "Karyopherin subunit alpha 2" P52292 17 68035636-68047364 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 195.6" "Cell type enhanced" "Detected in all" "Early spermatids: 805.7;Extravillous trophoblasts: 357.8;Late primary spermatocytes: 1344.4;Late spermatids: 324.4;Oocytes: 534.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015460, HPA041270" Enhanced Supported Nucleoplasm,Cytosol Yes Yes 170000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 39: Testis - Nuclear processes" "Cluster 14: Neurons - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 203 Nucleoplasm Cytosol "CAB015460: , HPA041270: " "potential prognostic unfavorable (2.46e-4)" "unprognostic (7.03e-2)" "unprognostic (3.62e-2)" "unprognostic (3.04e-3)" "potential prognostic favorable (5.31e-4)" "unprognostic (1.89e-1)" "unprognostic (3.16e-1)" "unprognostic (2.58e-1)" "unprognostic (6.36e-3)" "unprognostic (2.64e-3)" "unprognostic (3.18e-3)" "potential prognostic unfavorable (3.93e-6)" "potential prognostic unfavorable (2.74e-5)" "validated prognostic unfavorable (1.53e-10)" "validated prognostic unfavorable (8.25e-8)" "potential prognostic unfavorable (5.62e-5)" "unprognostic (1.18e-3)" "unprognostic (6.14e-2)" "unprognostic (4.35e-2)" "unprognostic (4.04e-2)" "unprognostic (4.07e-2)" "potential prognostic unfavorable (2.68e-4)" "unprognostic (2.84e-2)" "unprognostic (6.26e-2)" "unprognostic (7.32e-2)" "unprognostic (1.46e-2)" "unprognostic (1.76e-1)" "unprognostic (6.70e-2)" "unprognostic (5.05e-2)" "unprognostic (8.12e-2)" "unprognostic (1.07e-1)" KPNA3 "hSRP1, IPOA4, SRP1gamma, SRP4" ENSG00000102753 "Karyopherin subunit alpha 3" O00505 13 49699320-49792682 "Human disease related genes, Predicted intracellular proteins, Transporters" "Host-virus interaction, Protein transport, Transport, Viral penetration into host nucleus, Virus entry into host cell" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 136.2;tongue: 88.0" "Cell type enhanced" "Detected in all" "Early spermatids: 428.6;Rod photoreceptor cells: 382.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046852, HPA077643" Approved Supported Nucleoplasm,Cytosol NA NA 15000 "Cluster 33: Non-specific - ATP binding" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 27: Non-specific - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" 112 Nucleoplasm Cytosol "HPA046852: , HPA077643: " "unprognostic (1.81e-2)" "unprognostic (1.53e-1)" "unprognostic (1.27e-1)" "unprognostic (1.09e-3)" "unprognostic (8.24e-2)" "unprognostic (1.15e-1)" "unprognostic (4.27e-3)" "unprognostic (1.54e-1)" "unprognostic (1.56e-2)" "unprognostic (3.91e-3)" "potential prognostic favorable (1.80e-4)" "unprognostic (1.47e-1)" "unprognostic (3.57e-2)" "unprognostic (3.73e-2)" "unprognostic (7.11e-2)" "unprognostic (1.46e-1)" "unprognostic (1.74e-2)" "unprognostic (1.27e-1)" "unprognostic (2.07e-1)" "unprognostic (1.44e-2)" "unprognostic (3.02e-3)" "unprognostic (1.59e-2)" "unprognostic (2.96e-2)" "unprognostic (6.34e-2)" "unprognostic (5.59e-2)" "unprognostic (6.21e-2)" "unprognostic (9.90e-3)" "unprognostic (1.72e-1)" "unprognostic (2.59e-1)" "unprognostic (4.03e-3)" "unprognostic (1.65e-1)" KPNA4 "IPOA3, MGC12217, MGC26703, QIP1, SRP3" ENSG00000186432 "Karyopherin subunit alpha 4" O00629 3 160495007-160565571 "Predicted intracellular proteins, Transporters" "Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "skeletal muscle: 116.7;tongue: 56.0" "Cell type enhanced" "Detected in all" "Neutrophils: 432.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034336, HPA043154, HPA045500" Enhanced Enhanced "Nucleoplasm,Nuclear membrane" NA NA 87000 "Cluster 35: Neutrophils - Protein binding" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 55: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 20: Non-specific - Transcription regulation" 119 Nucleoplasm "Nuclear membrane" "CAB034336: , HPA043154: , HPA045500: " "unprognostic (7.99e-2)" "unprognostic (2.99e-1)" "unprognostic (8.52e-3)" "unprognostic (1.18e-2)" "unprognostic (8.46e-3)" "unprognostic (2.95e-1)" "unprognostic (3.37e-1)" "unprognostic (4.64e-3)" "unprognostic (2.64e-1)" "unprognostic (1.48e-3)" "unprognostic (2.52e-3)" "unprognostic (5.40e-2)" "unprognostic (1.11e-1)" "unprognostic (8.89e-3)" "unprognostic (1.18e-2)" "unprognostic (4.93e-3)" "unprognostic (4.21e-3)" "unprognostic (1.26e-1)" "unprognostic (1.84e-1)" "unprognostic (2.20e-1)" "unprognostic (8.84e-3)" "unprognostic (7.49e-3)" "unprognostic (1.95e-3)" "unprognostic (1.77e-1)" "unprognostic (2.05e-1)" "unprognostic (7.37e-3)" "unprognostic (5.72e-1)" "unprognostic (5.96e-2)" "unprognostic (1.94e-1)" "unprognostic (1.51e-1)" "unprognostic (4.06e-3)" KPNA5 "IPOA6, SRP6" ENSG00000196911 "Karyopherin subunit alpha 5" O15131 6 116681187-116741867 "Predicted intracellular proteins, Transporters" "Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 39.2" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 386.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "CAB026464, HPA054037" Enhanced Supported Cytosol NA NA "Cluster 32: Basophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 32 Cytosol "CAB026464: , HPA054037: " "unprognostic (2.80e-2)" "unprognostic (1.39e-1)" "unprognostic (1.67e-2)" "unprognostic (8.89e-3)" "unprognostic (1.73e-3)" "unprognostic (8.95e-2)" "unprognostic (4.66e-3)" "unprognostic (8.37e-3)" "unprognostic (3.34e-1)" "unprognostic (2.71e-3)" "unprognostic (2.03e-2)" "potential prognostic favorable (1.07e-4)" "unprognostic (1.54e-1)" "potential prognostic unfavorable (5.30e-4)" "unprognostic (1.54e-1)" "unprognostic (1.42e-1)" "unprognostic (1.55e-1)" "unprognostic (1.25e-1)" "unprognostic (4.83e-2)" "unprognostic (3.48e-1)" "unprognostic (2.17e-1)" "unprognostic (9.28e-3)" "unprognostic (1.15e-2)" "unprognostic (2.72e-1)" "unprognostic (1.70e-3)" "unprognostic (1.77e-3)" "unprognostic (2.97e-1)" "unprognostic (7.83e-3)" "unprognostic (2.66e-1)" "unprognostic (6.01e-2)" "unprognostic (9.86e-2)" KPNA6 "FLJ11249, IPOA7, KPNA7, MGC17918" ENSG00000025800 "Karyopherin subunit alpha 6" O60684 1 32108056-32176563 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 171.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018863 Supported Approved Nucleoplasm,Cytosol NA NA 28000 "Cluster 13: Non-specific - Mitochondria" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 96 Cytosol Nucleoplasm "HPA018863: " "unprognostic (1.02e-1)" "unprognostic (2.26e-2)" "unprognostic (4.31e-2)" "unprognostic (5.04e-3)" "unprognostic (6.59e-3)" "unprognostic (8.19e-2)" "unprognostic (1.28e-1)" "unprognostic (2.35e-1)" "unprognostic (3.89e-2)" "unprognostic (4.77e-3)" "potential prognostic favorable (2.78e-4)" "unprognostic (1.63e-2)" "unprognostic (9.58e-2)" "potential prognostic unfavorable (3.41e-6)" "unprognostic (4.62e-3)" "unprognostic (1.87e-1)" "unprognostic (4.46e-2)" "unprognostic (4.63e-2)" "unprognostic (1.09e-1)" "unprognostic (8.29e-3)" "unprognostic (2.84e-1)" "unprognostic (1.52e-1)" "unprognostic (3.73e-2)" "unprognostic (2.32e-2)" "unprognostic (1.25e-1)" "unprognostic (8.10e-3)" "unprognostic (2.55e-1)" "unprognostic (4.44e-1)" "unprognostic (3.53e-1)" "unprognostic (8.98e-2)" "unprognostic (8.77e-2)" KPNA7 IPOA8 ENSG00000185467 "Karyopherin subunit alpha 7" A9QM74 7 99173572-99250075 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "ovary: 3.1;stomach 1: 3.4" "Cell type enriched" "Detected in some" 37 "Oocytes: 713.8" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in some" "Lung Adenocarcinoma (TCGA): 2.4;Pancreatic Adenocarcinoma (TCGA): 2.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "pancreatic cancer: 2.2" "Skin - Outer root sheath cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA031395 Uncertain NA NA "Cluster 75: Ovary - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 41: Oocytes - Oogenesis" 1 "HPA031395: " "unprognostic (4.86e-2)" "unprognostic (7.87e-3)" "unprognostic (1.84e-1)" "unprognostic (5.43e-3)" "potential prognostic unfavorable (7.58e-6)" "unprognostic (1.06e-1)" "unprognostic (4.29e-3)" KPNB1 "IMB1, Impnb, IPO1, IPOB, MGC2155, MGC2156, MGC2157, NTF97" ENSG00000108424 "Karyopherin subunit beta 1" Q14974 17 47649476-47685505 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 523.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029878, CAB034449, HPA050302" Supported Enhanced "Nucleoplasm,Nuclear membrane,Cytosol" Yes No 3400000 "Cluster 21: Neutrophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 27: Breast cancer - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" 237 "Nuclear membrane" "Nucleoplasm, Cytosol" "CAB034449: , HPA029878: , HPA050302: " "unprognostic (5.64e-2)" "unprognostic (2.77e-2)" "unprognostic (1.73e-2)" "unprognostic (1.91e-2)" "unprognostic (8.81e-3)" "unprognostic (1.38e-1)" "unprognostic (7.79e-2)" "unprognostic (2.92e-2)" "unprognostic (8.79e-3)" "potential prognostic unfavorable (2.31e-4)" "potential prognostic favorable (6.91e-5)" "unprognostic (4.31e-2)" "unprognostic (1.62e-2)" "unprognostic (1.04e-3)" "unprognostic (1.59e-3)" "unprognostic (2.12e-2)" "potential prognostic unfavorable (4.21e-5)" "unprognostic (1.09e-1)" "unprognostic (5.30e-2)" "unprognostic (2.89e-1)" "unprognostic (3.93e-2)" "unprognostic (5.43e-3)" "potential prognostic unfavorable (7.58e-5)" "unprognostic (1.98e-2)" "potential prognostic favorable (6.42e-4)" "unprognostic (1.17e-2)" "unprognostic (2.87e-2)" "unprognostic (1.56e-1)" "unprognostic (1.97e-1)" "unprognostic (1.28e-3)" "unprognostic (6.44e-2)" KPRP C1orf45 ENSG00000203786 "Keratinocyte proline rich protein" Q5T749 1 152758025-152762056 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "skin 1: 318.1" "Cell type enriched" "Detected in some" 29 "Esophageal apical cells: 75.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "Head and Neck Squamous Cell Carcinoma (TCGA): 9.1;Skin Cutaneous Melanoma (TCGA): 26.0" "Region enriched" "Detected in single" 6 "basal ganglia: 1.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 35 "thyroid cancer: 19.3" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" "HPA031988, HPA031990" Enhanced NA NA 36000000 "Cluster 37: Skin - Keratinization" "Cluster 33: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 84: Apical squamous epithelium - Cornification" 113 "HPA031988: , HPA031990: " "unprognostic (4.77e-2)" "unprognostic (1.70e-1)" KPTN "2E4, KICS4" ENSG00000118162 "Kaptin, actin binding protein" Q9Y664 19 47475150-47484265 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 23.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "plasmacytoid DC: 23.9" "Lineage enriched" "Detected in all" 4 "dendritic cells: 23.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041710, HPA041796" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 35: RS4;11 - Unknown function" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 22 "Plasma membrane" "Nucleoplasm, Vesicles" "HPA041710: , HPA041796: " "unprognostic (7.99e-2)" "unprognostic (1.23e-2)" "unprognostic (6.71e-2)" "unprognostic (2.91e-2)" "unprognostic (2.64e-2)" "unprognostic (4.70e-3)" "unprognostic (3.04e-2)" "unprognostic (4.82e-2)" "unprognostic (3.30e-2)" "unprognostic (1.44e-1)" "unprognostic (1.83e-2)" "unprognostic (6.55e-3)" "unprognostic (1.84e-1)" "potential prognostic unfavorable (3.57e-6)" "unprognostic (3.61e-2)" "unprognostic (2.21e-3)" "unprognostic (3.10e-1)" "unprognostic (1.01e-1)" "unprognostic (1.09e-1)" "unprognostic (3.28e-3)" "unprognostic (2.33e-1)" "unprognostic (1.30e-1)" "unprognostic (4.11e-2)" "unprognostic (3.26e-2)" "unprognostic (1.93e-1)" "unprognostic (8.59e-2)" "unprognostic (4.50e-2)" "unprognostic (1.74e-1)" "unprognostic (2.77e-1)" "unprognostic (4.00e-2)" "unprognostic (5.86e-3)" KRAS "K-Ras4B, KRAS1, KRAS2" ENSG00000133703 "KRAS proto-oncogene, GTPase" P01116 12 25205246-25250936 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, RAS pathway related proteins" Hydrolase "Cancer-related genes, Cardiomyopathy, Deafness, Disease variant, Ectodermal dysplasia, FDA approved drug targets, Intellectual disability, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 503.6;Neutrophils: 509.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Bile duct cancer: 225.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049830, HPA072761" Approved Supported Cytosol NA NA 2200000 "Cluster 7: Non-specific - Innate immune response" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 14: Neurons - Synaptic function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 446 Cytosol "HPA049830: , HPA072761: " "unprognostic (3.53e-2)" "unprognostic (7.54e-3)" "unprognostic (2.14e-1)" "potential prognostic unfavorable (4.34e-4)" "unprognostic (9.27e-2)" "unprognostic (1.13e-1)" "unprognostic (1.23e-1)" "unprognostic (1.97e-1)" "unprognostic (3.55e-1)" "unprognostic (9.60e-2)" "potential prognostic favorable (1.57e-6)" "unprognostic (2.69e-2)" "unprognostic (7.19e-3)" "unprognostic (2.56e-2)" "unprognostic (2.37e-1)" "potential prognostic unfavorable (3.46e-4)" "unprognostic (8.79e-2)" "unprognostic (4.19e-2)" "unprognostic (5.92e-2)" "unprognostic (1.21e-1)" "unprognostic (7.44e-2)" "unprognostic (2.38e-3)" "unprognostic (5.24e-3)" "unprognostic (6.67e-2)" "unprognostic (1.25e-1)" "unprognostic (3.71e-2)" "unprognostic (1.74e-1)" "unprognostic (2.26e-1)" "unprognostic (2.20e-1)" "unprognostic (1.47e-2)" "unprognostic (3.46e-1)" KRBA1 KIAA1862 ENSG00000133619 "KRAB-A domain containing 1" A5PL33 7 149714781-149734575 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 37.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 48.2;Corticotrophs: 20.2;Epicardial cells: 18.2;Müller glia: 17.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 31.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Pituitary gland - Corticotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021237, HPA050448" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 18: Non-specific - Translation" "Cluster 35: Non-specific - Mixed function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" Nucleoplasm Cytosol "HPA021237: , HPA050448: " "unprognostic (1.15e-1)" "unprognostic (1.35e-1)" "unprognostic (1.85e-1)" "unprognostic (2.02e-2)" "unprognostic (9.70e-2)" "unprognostic (1.41e-1)" "unprognostic (4.56e-3)" "unprognostic (2.55e-1)" "unprognostic (1.28e-1)" "unprognostic (1.14e-2)" "potential prognostic favorable (2.60e-4)" "unprognostic (1.44e-1)" "unprognostic (2.67e-1)" "potential prognostic unfavorable (5.30e-5)" "unprognostic (1.29e-2)" "unprognostic (5.49e-3)" "unprognostic (1.57e-1)" "unprognostic (2.83e-1)" "unprognostic (1.70e-1)" "unprognostic (7.90e-2)" "unprognostic (3.88e-2)" "unprognostic (1.49e-3)" "unprognostic (1.55e-2)" "unprognostic (5.08e-2)" "unprognostic (1.85e-1)" "unprognostic (1.21e-2)" "unprognostic (7.96e-2)" "unprognostic (9.26e-2)" "unprognostic (1.40e-1)" "unprognostic (1.71e-1)" KRBA2 ENSG00000184619 "KRAB-A domain containing 2" Q6ZNG9 17 8356902-8376704 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "retina: 31.9" "Cell type enhanced" "Detected in many" "Astrocytes: 32.7;Bergmann glia: 29.5;Choroid plexus epithelial cells: 35.4;Myonuclei: 23.3;Oligodendrocytes: 23.0;Rod photoreceptor cells: 52.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 10.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes" HPA022849 Approved Approved Nucleoplasm NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" Nucleoplasm "HPA022849: " "unprognostic (3.07e-3)" "unprognostic (1.91e-2)" "unprognostic (9.65e-2)" "unprognostic (7.24e-2)" "unprognostic (7.58e-2)" "unprognostic (3.57e-1)" "unprognostic (1.98e-3)" "potential prognostic favorable (3.16e-5)" "unprognostic (3.88e-2)" "unprognostic (4.13e-1)" "potential prognostic favorable (2.14e-6)" "potential prognostic favorable (9.37e-4)" "unprognostic (9.04e-2)" "unprognostic (2.35e-2)" "unprognostic (5.54e-2)" "unprognostic (4.26e-2)" "unprognostic (7.24e-2)" "potential prognostic favorable (1.72e-4)" "unprognostic (2.56e-2)" "unprognostic (1.62e-1)" "unprognostic (7.36e-2)" "unprognostic (6.59e-3)" "unprognostic (2.02e-2)" "unprognostic (1.80e-1)" "unprognostic (3.90e-2)" "unprognostic (1.79e-1)" KRBOX1 ENSG00000240747 "KRAB box domain containing 1" C9JBD0 3 42936386-42942792 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 20 "testis: 191.9" "Cell type enriched" "Detected in some" 4 "Late primary spermatocytes: 5.6" "Cell type enhanced" "Detected in some" "vascular associated smooth muscle cell: 2.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 4 "NK-cell: 4.0" "Lineage enriched" "Detected in many" 4 "NK-cells: 4.0" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" HPA046901 Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 6: Testis - Spermatogenesis" "Cluster 55: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" Nucleoplasm "Golgi apparatus" "HPA046901: " "unprognostic (1.29e-1)" "unprognostic (1.16e-1)" "unprognostic (3.45e-1)" "unprognostic (3.16e-1)" "unprognostic (2.32e-3)" "unprognostic (2.04e-1)" "unprognostic (6.12e-2)" "unprognostic (3.72e-2)" "unprognostic (1.48e-1)" "unprognostic (6.56e-2)" "unprognostic (1.63e-1)" "unprognostic (3.55e-3)" "potential prognostic favorable (1.98e-4)" "unprognostic (1.15e-1)" "unprognostic (1.47e-2)" "unprognostic (3.81e-1)" "unprognostic (1.57e-1)" "unprognostic (1.39e-1)" "unprognostic (1.13e-1)" "unprognostic (3.30e-2)" "unprognostic (1.82e-2)" "unprognostic (1.67e-1)" "unprognostic (2.63e-1)" "unprognostic (3.98e-3)" "unprognostic (1.95e-1)" "unprognostic (7.31e-2)" "unprognostic (1.31e-2)" KRBOX4 "FLJ20344, ZNF673" ENSG00000147121 "KRAB box domain containing 4" Q5JUW0 X 46447292-46497422 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bergmann glia: 91.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA065295 Approved Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 64: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 36: Non-specific - mRNA processing" "Cluster 7: Non-specific - Transcription" 1 Nucleoplasm "HPA065295: " "unprognostic (6.19e-2)" "unprognostic (5.71e-2)" "unprognostic (3.61e-2)" "unprognostic (1.75e-1)" "unprognostic (1.01e-1)" "unprognostic (2.29e-1)" "unprognostic (1.69e-2)" "unprognostic (3.56e-1)" "potential prognostic unfavorable (2.51e-4)" "unprognostic (1.47e-1)" "unprognostic (1.62e-2)" "unprognostic (1.59e-1)" "potential prognostic unfavorable (1.96e-5)" "unprognostic (1.57e-2)" "unprognostic (4.62e-3)" "unprognostic (3.50e-2)" "unprognostic (1.07e-2)" "unprognostic (2.78e-1)" "unprognostic (3.07e-1)" "unprognostic (1.94e-1)" "potential prognostic unfavorable (7.13e-4)" "unprognostic (6.80e-2)" "unprognostic (6.02e-2)" "unprognostic (6.15e-3)" "unprognostic (1.47e-2)" "unprognostic (5.66e-2)" "unprognostic (2.69e-1)" "unprognostic (1.08e-1)" "unprognostic (3.16e-1)" KRBOX5 ZNF720 ENSG00000197302 "KRAB box domain containing 5" Q7Z2F6 16 31713229-31794869 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA041570 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 32: Basophils - Transcription" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 25: Non-specific - Transcription" "Cluster 54: Non-specific - Transcription" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 1 Cytosol "Nucleoplasm, Plasma membrane" "HPA041570: " "unprognostic (3.16e-2)" "unprognostic (2.98e-1)" "unprognostic (2.64e-1)" "potential prognostic unfavorable (6.78e-4)" "unprognostic (2.90e-1)" "unprognostic (6.88e-2)" "unprognostic (1.16e-1)" "unprognostic (1.52e-1)" "unprognostic (4.62e-2)" "unprognostic (4.40e-3)" "potential prognostic favorable (9.92e-4)" "unprognostic (5.14e-2)" "unprognostic (1.00e-2)" "unprognostic (9.04e-2)" "unprognostic (2.95e-2)" "unprognostic (2.31e-1)" "unprognostic (8.42e-2)" "unprognostic (9.73e-3)" "unprognostic (5.41e-1)" "unprognostic (2.74e-1)" "potential prognostic unfavorable (2.99e-4)" "unprognostic (4.50e-1)" "unprognostic (1.36e-2)" "unprognostic (3.40e-2)" "unprognostic (4.81e-2)" "unprognostic (3.73e-1)" "unprognostic (2.26e-1)" "unprognostic (2.26e-1)" "unprognostic (2.75e-1)" "unprognostic (7.78e-2)" "unprognostic (6.51e-3)" KRCC1 FLJ22333 ENSG00000172086 "Lysine rich coiled-coil 1" Q9NPI7 2 88027205-88064252 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 457.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045618, HPA052666" Approved Approved Nucleoli,Cytosol NA NA "Cluster 32: Basophils - Transcription" "Cluster 76: Non-specific - Metabolism" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 84: Apical squamous epithelium - Cornification" 3 Cytosol Nucleoli "HPA045618: , HPA052666: " "unprognostic (4.54e-2)" "unprognostic (2.19e-1)" "unprognostic (4.10e-2)" "unprognostic (1.59e-1)" "unprognostic (2.78e-2)" "unprognostic (1.22e-2)" "unprognostic (7.66e-2)" "unprognostic (5.08e-3)" "unprognostic (4.23e-2)" "unprognostic (2.65e-2)" "potential prognostic favorable (6.79e-4)" "unprognostic (2.79e-1)" "unprognostic (3.51e-2)" "unprognostic (1.14e-1)" "unprognostic (1.20e-1)" "unprognostic (2.17e-2)" "unprognostic (3.75e-1)" "unprognostic (1.18e-3)" "unprognostic (1.66e-1)" "unprognostic (2.09e-1)" "unprognostic (2.50e-3)" "unprognostic (2.07e-1)" "unprognostic (1.88e-1)" "unprognostic (2.20e-1)" "unprognostic (1.55e-1)" "potential prognostic unfavorable (1.78e-4)" "unprognostic (1.42e-2)" "unprognostic (3.16e-1)" "unprognostic (2.18e-1)" "unprognostic (2.58e-1)" "unprognostic (2.90e-1)" KREMEN1 "KREMEN, KRM1" ENSG00000183762 "Kringle containing transmembrane protein 1" Q96MU8 22 29073035-29168333 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Wnt signaling pathway" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bergmann glia: 152.0;Esophageal apical cells: 207.4;Myosatellite cells: 225.6;Neutrophils: 501.1" "Cell type enhanced" "Detected in all" "Bergmann glia: 158.8;fibroblast: 168.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 1.3;neutrophil: 4.5" "Lineage enriched" "Detected in single" 7 "granulocytes: 4.5" "Cancer enhanced" "Detected in all" "cervical cancer: 55.4" "Skeletal muscle - Skeletal myocytes, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA No 460000 "Cluster 35: Neutrophils - Protein binding" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 33: Neurons - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 24: Neutrophils - Innate immunity signal integration" 1 "unprognostic (1.52e-1)" "unprognostic (3.17e-1)" "unprognostic (1.53e-1)" "unprognostic (4.00e-2)" "unprognostic (2.53e-1)" "unprognostic (1.74e-1)" "unprognostic (1.68e-1)" "unprognostic (2.21e-1)" "unprognostic (1.20e-2)" "unprognostic (1.14e-1)" "potential prognostic favorable (2.63e-4)" "unprognostic (2.78e-2)" "unprognostic (1.87e-1)" "potential prognostic unfavorable (7.19e-4)" "unprognostic (6.93e-2)" "unprognostic (5.57e-3)" "unprognostic (2.09e-2)" "unprognostic (7.80e-2)" "unprognostic (7.33e-3)" "unprognostic (2.10e-1)" "unprognostic (4.33e-2)" "unprognostic (9.74e-2)" "unprognostic (5.90e-2)" "unprognostic (1.26e-1)" "unprognostic (2.09e-2)" "potential prognostic unfavorable (1.87e-4)" "unprognostic (7.91e-3)" "unprognostic (1.13e-1)" "unprognostic (1.68e-1)" "unprognostic (1.76e-1)" "unprognostic (6.92e-3)" KREMEN2 "KRM2, MGC10791" ENSG00000131650 "Kringle containing transmembrane protein 2" Q8NCW0 16 2964216-2968383 "Predicted intracellular proteins, Predicted membrane proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "retina: 3.8;skin 1: 7.5" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 14.1;Cone photoreceptor cells: 8.3;Differentiating spermatogonia: 8.2;Early primary spermatocytes: 29.5;Epididymal basal cells: 14.7;Esophageal basal cells: 6.9;Goblet cells: 18.6;Medullary thymic epithelial cells: 16.8;Retinal ganglion cells: 7.7;Rod photoreceptor cells: 33.0;Tuft cells: 46.1" "Cell type enriched" "Detected in some" 9 "hippocampal CA4: 13.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.2;naive B-cell: 1.3" "Lineage enhanced" "Detected in single" "B-cells: 1.3" "Cancer enhanced" "Detected in many" "Rhabdoid: 38.8" "Prostate - Prostate glandular cells, Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA003223 Uncertain "Intracellular and membrane" Other NA NA "Cluster 2: Non-specific - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 70: Intestinal goblet cells - Mucin production" "HPA003223: " "unprognostic (1.15e-1)" "unprognostic (7.07e-2)" "unprognostic (3.12e-1)" "unprognostic (2.73e-1)" "unprognostic (6.80e-3)" "unprognostic (3.07e-1)" "unprognostic (7.65e-2)" "unprognostic (1.38e-1)" "potential prognostic unfavorable (1.29e-4)" "unprognostic (3.79e-2)" "unprognostic (1.60e-1)" "unprognostic (1.54e-1)" "unprognostic (5.65e-2)" "unprognostic (1.44e-1)" "unprognostic (7.79e-2)" "unprognostic (1.94e-1)" "unprognostic (1.31e-1)" "unprognostic (3.55e-2)" "unprognostic (6.98e-2)" "unprognostic (3.43e-1)" "unprognostic (3.31e-2)" KRI1 FLJ12949 ENSG00000129347 "KRI1 homolog" Q8N9T8 19 10553085-10566031 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043110, HPA043574" Approved Enhanced Nucleoli Yes No "Cluster 30: Non-specific - DNA binding" "Cluster 49: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 23: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 22 Nucleoli "HPA043110: , HPA043574: " "unprognostic (1.58e-1)" "unprognostic (1.08e-1)" "unprognostic (4.69e-2)" "unprognostic (4.11e-2)" "unprognostic (3.20e-3)" "unprognostic (1.11e-2)" "unprognostic (1.84e-2)" "unprognostic (1.16e-3)" "unprognostic (1.93e-3)" "potential prognostic unfavorable (1.01e-5)" "unprognostic (6.75e-2)" "unprognostic (1.05e-1)" "unprognostic (3.21e-1)" "potential prognostic unfavorable (8.36e-4)" "unprognostic (6.08e-2)" "unprognostic (1.41e-1)" "unprognostic (3.76e-3)" "unprognostic (1.57e-2)" "unprognostic (4.55e-3)" "unprognostic (7.44e-2)" "unprognostic (1.58e-1)" "unprognostic (1.78e-1)" "unprognostic (1.98e-3)" "unprognostic (1.00e-2)" "unprognostic (1.71e-1)" "unprognostic (1.12e-1)" "unprognostic (2.62e-1)" "unprognostic (8.80e-2)" "unprognostic (9.99e-2)" "unprognostic (7.84e-2)" "unprognostic (3.02e-1)" KRIT1 "CAM, CCM1" ENSG00000001631 "KRIT1 ankyrin repeat containing" O00522 7 92197498-92246166 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Angiogenesis "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 9 "Distal convoluted tubule cells: 119.6;Loop of henle epithelial cells: 96.4;Papillary tip epithelial cells: 60.7;Podocytes: 106.6;Proximal tubule cells: 111.3;Renal collecting duct intercalated cells: 106.9;Renal collecting duct principal cells: 82.8;Renal connecting tubule cells: 90.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049606 Supported Uncertain Vesicles NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 55: Non-specific - Transcription" "Cluster 39: Non-specific - Transcription" "Cluster 105: Non-specific - Mixed function" 12 Vesicles "HPA049606: " "unprognostic (2.64e-1)" "unprognostic (1.22e-1)" "unprognostic (2.46e-2)" "unprognostic (1.24e-2)" "unprognostic (3.04e-2)" "unprognostic (3.60e-2)" "unprognostic (4.26e-1)" "unprognostic (5.78e-3)" "unprognostic (3.67e-2)" "potential prognostic unfavorable (2.11e-4)" "potential prognostic favorable (2.18e-6)" "unprognostic (3.66e-3)" "unprognostic (1.91e-1)" "unprognostic (3.96e-3)" "unprognostic (1.45e-1)" "unprognostic (3.44e-1)" "unprognostic (1.13e-1)" "unprognostic (2.20e-2)" "unprognostic (6.48e-2)" "unprognostic (6.60e-2)" "unprognostic (4.64e-2)" "unprognostic (9.81e-2)" "potential prognostic unfavorable (3.48e-4)" "unprognostic (1.38e-1)" "unprognostic (2.35e-2)" "unprognostic (2.21e-1)" "unprognostic (8.46e-2)" "unprognostic (7.58e-2)" "unprognostic (3.02e-1)" "unprognostic (5.56e-2)" "unprognostic (1.51e-1)" KRR1 "HRB2, RIP-1" ENSG00000111615 "KRR1 small subunit processome component homolog" Q13601 12 75490863-75511636 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043433, HPA051690" Approved Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 3: Non-specific - Nuclear processes" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 147 "Nucleoli, Nucleoli rim" "Nucleoplasm, Mitotic chromosome" "HPA043433: , HPA051690: " "unprognostic (3.54e-2)" "unprognostic (9.71e-2)" "unprognostic (3.20e-2)" "unprognostic (2.28e-2)" "unprognostic (2.56e-1)" "unprognostic (1.62e-1)" "unprognostic (1.05e-1)" "unprognostic (1.80e-1)" "unprognostic (2.03e-2)" "unprognostic (2.22e-3)" "potential prognostic favorable (7.27e-7)" "unprognostic (1.65e-3)" "unprognostic (3.10e-1)" "unprognostic (2.43e-3)" "unprognostic (3.51e-2)" "unprognostic (4.80e-3)" "unprognostic (7.79e-3)" "unprognostic (7.70e-3)" "unprognostic (1.04e-1)" "unprognostic (2.24e-1)" "unprognostic (8.77e-3)" "unprognostic (3.84e-3)" "unprognostic (4.92e-3)" "unprognostic (5.57e-2)" "unprognostic (5.30e-2)" "unprognostic (8.21e-2)" "unprognostic (1.37e-1)" "unprognostic (9.55e-2)" "unprognostic (1.48e-1)" "unprognostic (1.13e-1)" "unprognostic (2.41e-1)" KRT1 "EHK1, KRT1A" ENSG00000167768 "Keratin 1" P04264 12 52674736-52680407 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Ichthyosis, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "skin 1: 12288.0" "Cell type enriched" "Detected in some" 10 "Suprabasal keratinocytes: 6388.9" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Head and Neck Squamous Cell Carcinoma (TCGA): 456.5;Skin Cutaneous Melanoma (TCGA): 862.0" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "memory CD4 T-cell: 2.3" "Lineage enriched" "Detected in single" 23 "T-cells: 2.3" "Group enriched" "Detected in some" 5 "Bladder cancer: 10.9;Esophageal cancer: 23.0;head and neck cancer: 17.4" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Not detected" "Not detected" "CAB002153, HPA017917, HPA062908" Enhanced NA NA 10000000000 "Cluster 11: T-cells - Unknown function" "Cluster 37: Skin - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 26: Keratinocytes - Keratinization" 48 "CAB002153: , HPA017917: , HPA062908: " "unprognostic (1.58e-1)" "unprognostic (2.45e-1)" "unprognostic (2.30e-3)" "unprognostic (2.00e-1)" "unprognostic (1.25e-1)" "unprognostic (2.02e-1)" "unprognostic (7.31e-2)" "unprognostic (3.71e-2)" KRT10 "CK10, K10, KPP" ENSG00000186395 "Keratin 10" P13645 17 40818117-40822614 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 17 "skin 1: 14580.6" "Cell type enriched" "Detected in many" 8 "Suprabasal keratinocytes: 7879.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Head and Neck Squamous Cell Carcinoma (TCGA): 446.1;Skin Cutaneous Melanoma (TCGA): 876.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Rhabdoid: 214.5" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000132, HPA012014" Enhanced "Secreted in other tissues" "No annotated function" NA NA 8100000000 "Cluster 45: Eosinophils - Unknown function" "Cluster 37: Skin - Keratinization" "Cluster 55: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 26: Keratinocytes - Keratinization" 11 "CAB000132: , HPA012014: " "unprognostic (2.60e-1)" "unprognostic (5.90e-2)" "unprognostic (3.61e-2)" "unprognostic (4.48e-2)" "unprognostic (3.42e-1)" "unprognostic (2.34e-2)" "unprognostic (3.70e-3)" "unprognostic (3.48e-2)" "unprognostic (3.42e-1)" "potential prognostic unfavorable (2.79e-4)" "potential prognostic unfavorable (1.34e-4)" "unprognostic (3.45e-3)" "unprognostic (4.50e-2)" "unprognostic (5.02e-2)" "unprognostic (1.70e-3)" "unprognostic (1.80e-2)" "unprognostic (2.59e-1)" "unprognostic (1.86e-1)" "unprognostic (1.11e-1)" "unprognostic (1.53e-1)" "unprognostic (7.27e-2)" "unprognostic (6.64e-2)" "potential prognostic unfavorable (1.62e-5)" "unprognostic (1.02e-1)" "unprognostic (6.49e-2)" "unprognostic (2.54e-1)" "unprognostic (1.21e-2)" "unprognostic (1.65e-1)" "unprognostic (1.09e-1)" "unprognostic (4.01e-3)" "unprognostic (3.15e-1)" KRT12 K12 ENSG00000187242 "Keratin 12" Q99456 17 40861303-40867223 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Corneal dystrophy, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 35 "Ocular epithelial cells: 913.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Bone cancer: 1.0" "Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA055217, HPA055835" Enhanced NA NA 37000000 "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 100: Stratified epithelial cells - Barrier functions" "HPA055217: , HPA055835: " "unprognostic (1.65e-1)" KRT13 "CK13, K13, MGC161462, MGC3781" ENSG00000171401 "Keratin 13" P13646 17 41500981-41505705 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 11736.9;esophagus: 38499.7;vagina: 12358.9" "Group enriched" "Detected in many" 5 "Esophageal apical cells: 297830.3;Esophageal suprabasal cells: 146075.8" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "Bladder Urothelial Carcinoma (TCGA): 1729.0;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 2656.8;Head and Neck Squamous Cell Carcinoma (TCGA): 2165.1;Lung Squamous Cell Carcinoma (TCGA): 729.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "cervical cancer: 3545.3" "Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Urothelial cells" "CAB000133, HPA030877, HPA069771" Enhanced Enhanced "Intermediate filaments" NA NA 420000000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 35 "Intermediate filaments" "CAB000133: , HPA030877: , HPA069771: " "unprognostic (1.01e-3)" "unprognostic (3.05e-1)" "unprognostic (3.63e-2)" "unprognostic (2.30e-1)" "unprognostic (2.77e-1)" "unprognostic (8.93e-3)" "potential prognostic unfavorable (1.08e-4)" "unprognostic (1.81e-1)" "unprognostic (3.26e-1)" "unprognostic (3.02e-2)" "unprognostic (7.37e-2)" "unprognostic (9.56e-2)" "unprognostic (4.75e-3)" "unprognostic (1.77e-1)" "potential prognostic unfavorable (1.57e-5)" "unprognostic (4.85e-3)" "unprognostic (4.56e-1)" "unprognostic (5.07e-2)" "unprognostic (1.21e-1)" "unprognostic (2.38e-1)" "unprognostic (7.46e-2)" "unprognostic (2.09e-1)" KRT14 "EBS3, EBS4" ENSG00000186847 "Keratin 14" P02533 17 41582279-41586895 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Ectodermal dysplasia, Epidermolysis bullosa, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 6581.3" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 32869.7;Esophageal basal cells: 8944.1;Suprabasal keratinocytes: 11198.6" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "Head and Neck Squamous Cell Carcinoma (TCGA): 14138.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "head and neck cancer: 2098.9" "Breast - Breast myoepithelial cells, Minor Salivary Gland - Minor salivary gland basal cells, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.5" "CAB000134, HPA000452, HPA000539, HPA023040" Enhanced Enhanced "Intermediate filaments" NA NA 1100000000 "Cluster 37: Skin - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 26: Keratinocytes - Keratinization" 39 "Intermediate filaments" "CAB000134: , HPA000452: , HPA000539: , HPA023040: " "unprognostic (1.48e-3)" "potential prognostic favorable (1.36e-4)" "unprognostic (1.96e-1)" "unprognostic (2.84e-1)" "unprognostic (3.57e-2)" "unprognostic (5.39e-2)" "unprognostic (4.11e-1)" "potential prognostic unfavorable (3.81e-4)" "unprognostic (2.35e-1)" "unprognostic (1.86e-1)" "unprognostic (1.79e-1)" "unprognostic (1.77e-1)" "unprognostic (4.43e-3)" "unprognostic (1.32e-1)" "unprognostic (2.71e-3)" "unprognostic (2.61e-1)" "unprognostic (9.65e-2)" "unprognostic (2.43e-1)" "unprognostic (1.53e-2)" "unprognostic (6.60e-2)" KRT15 "CK15, K15, K1CO" ENSG00000171346 "Keratin 15" P19012 17 41513745-41522529 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 1708.0;skin 1: 1245.8;vagina: 627.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 2280.7;Basal prostatic cells: 1586.7;Breast secretory cells: 1528.1;Esophageal basal cells: 8444.0;Ocular epithelial cells: 966.0;Respiratory basal cells: 1473.1;Submucosal glandular cells: 919.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 966.5;Head and Neck Squamous Cell Carcinoma (TCGA): 610.0;Lung Squamous Cell Carcinoma (TCGA): 787.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 522.2;head and neck cancer: 469.4" "Minor Salivary Gland - Minor salivary gland basal cells, Testis - Late spermatids" "Region enhanced" "Detected in single" "white matter: 1.9" "Not detected" "Not detected" "HPA023910, HPA024554" Enhanced Supported "Nucleoplasm,Intermediate filaments" No No 220000000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 26: Keratinocytes - Keratinization" 153 "Intermediate filaments" Nucleoplasm "HPA023910: , HPA024554: " "unprognostic (1.39e-2)" "potential prognostic favorable (5.79e-4)" "unprognostic (5.50e-3)" "unprognostic (9.09e-2)" "unprognostic (2.76e-2)" "unprognostic (5.84e-2)" "unprognostic (1.98e-1)" "unprognostic (1.02e-1)" "unprognostic (1.33e-1)" "unprognostic (1.36e-1)" "unprognostic (5.63e-2)" "unprognostic (1.85e-2)" "unprognostic (2.05e-1)" "unprognostic (3.12e-2)" "unprognostic (1.68e-1)" "unprognostic (1.08e-3)" "unprognostic (2.18e-3)" "unprognostic (1.37e-1)" "unprognostic (8.96e-3)" "unprognostic (7.92e-2)" "unprognostic (1.98e-1)" "unprognostic (2.38e-3)" "unprognostic (1.35e-1)" "potential prognostic favorable (1.72e-4)" "unprognostic (1.09e-1)" KRT16 NEPPK ENSG00000186832 "Keratin 16" P08779 17 41609778-41615899 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Ectodermal dysplasia, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 437.0;esophagus: 1008.0;skin 1: 348.3;vagina: 476.3" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 2585.0;Esophageal apical cells: 5443.3;Esophageal basal cells: 1830.8;Esophageal suprabasal cells: 5797.7;Suprabasal keratinocytes: 8134.1" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Head and Neck Squamous Cell Carcinoma (TCGA): 7107.0" "Group enriched" "Detected in some" 4 "cerebellum: 9.8;cerebral cortex: 2.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Esophageal cancer: 107.9;head and neck cancer: 324.1" "Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Urothelial cells, Skin - Outer root sheath cells" "Not detected" "Not detected" "CAB000136, HPA000539" Approved Approved "Intermediate filaments" NA NA 950000000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 72 "Intermediate filaments" "CAB000136: , HPA000539: " "unprognostic (3.51e-1)" "unprognostic (7.89e-3)" "unprognostic (3.10e-1)" "unprognostic (8.07e-2)" "unprognostic (1.37e-1)" "unprognostic (3.85e-1)" "unprognostic (5.50e-3)" "unprognostic (8.41e-2)" "unprognostic (2.37e-1)" "potential prognostic unfavorable (4.47e-6)" "unprognostic (3.15e-2)" "unprognostic (8.15e-2)" "unprognostic (2.95e-2)" "unprognostic (1.36e-2)" "unprognostic (3.06e-1)" "potential prognostic unfavorable (1.50e-5)" "unprognostic (2.14e-3)" "unprognostic (7.12e-3)" "unprognostic (2.15e-1)" "unprognostic (3.15e-1)" "unprognostic (1.93e-1)" "unprognostic (3.69e-1)" "unprognostic (1.30e-1)" "unprognostic (8.63e-2)" "unprognostic (8.42e-2)" KRT17 PCHC1 ENSG00000128422 "Keratin 17" Q04695 17 41619442-41624842 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Ectodermal dysplasia, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 409.9;skin 1: 953.7;urinary bladder: 590.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 2277.6;Breast myoepithelial cells: 4203.0;Endometrial secretory cells: 1827.0;Epididymal basal cells: 6663.4;Esophageal apical cells: 2167.8;Esophageal basal cells: 1467.2;Esophageal suprabasal cells: 2048.6;Ocular epithelial cells: 1007.4;Respiratory basal cells: 1606.8;Salivary basal cells: 1414.2;Salivary myoepithelial cells: 1788.0;Suprabasal keratinocytes: 2631.4;Urothelial cells: 1726.6" "Cell type enriched" "Detected in some" 5 "deep-layer corticothalamic and 6b: 20.1" "Cancer enhanced" "Detected in all" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 4447.8;Head and Neck Squamous Cell Carcinoma (TCGA): 9171.1" "Region enhanced" "Detected in many" "cerebral cortex: 11.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 2953.8;head and neck cancer: 2649.4" "Breast - Breast myoepithelial cells, Lung - Respiratory ciliated cells, Prostate - Prostate basal glandular cells, Skin - Outer root sheath cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB000029, HPA000452, HPA000453, HPA000539, HPA045062" Enhanced Enhanced "Intermediate filaments" Yes No 380000000 "Cluster 58: Skin - Keratinization" "Cluster 53: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 26: Keratinocytes - Keratinization" 26 "Intermediate filaments" "CAB000029: , HPA000452: , HPA000453: , HPA000539: , HPA045062: " "unprognostic (4.86e-2)" "potential prognostic favorable (3.36e-4)" "unprognostic (3.67e-1)" "unprognostic (1.71e-1)" "unprognostic (1.54e-1)" "unprognostic (9.90e-2)" "potential prognostic unfavorable (5.58e-5)" "unprognostic (2.16e-1)" "unprognostic (1.23e-1)" "potential prognostic unfavorable (5.19e-6)" "unprognostic (5.08e-3)" "unprognostic (1.20e-1)" "potential prognostic unfavorable (7.57e-4)" "unprognostic (8.79e-2)" "unprognostic (4.92e-3)" "unprognostic (7.70e-2)" "unprognostic (1.31e-1)" "unprognostic (1.15e-1)" "unprognostic (7.92e-2)" "unprognostic (3.07e-1)" "unprognostic (1.68e-3)" "potential prognostic unfavorable (6.71e-4)" "unprognostic (7.81e-2)" "unprognostic (8.23e-3)" "unprognostic (3.44e-2)" "unprognostic (1.97e-1)" "unprognostic (1.83e-1)" "unprognostic (1.22e-2)" "unprognostic (3.35e-1)" "unprognostic (3.38e-3)" KRT18 ENSG00000111057 "Keratin 18" P05783 12 52948871-52952906 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Host-virus interaction" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 2617.6;Colonocytes: 3183.4;Cytotrophoblasts: 3515.5;Extravillous trophoblasts: 7124.1;Fallopian secretory cells: 2769.1;Goblet cells: 3371.7;Migrating cytotrophoblasts: 7756.7;Pancreatic duct cells: 2851.6;Syncytiotrophoblasts: 9371.6;Tuft cells: 3827.4" "Group enriched" "Detected in many" 5 "choroid plexus epithelial cell: 11.4;lower rhombic lip: 45.2" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in all" 5 "choroid plexus: 72.5;hypothalamus: 28.1;medulla oblongata: 35.3;pons: 63.2" "Immune cell enriched" "Detected in many" 7 "basophil: 76.8" "Lineage enriched" "Detected in many" 7 "granulocytes: 76.8" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Corticotropes, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 15.6" "CAB000008, CAB000030, HPA001605" Enhanced Supported Cytosol NA NA 39000000 "Cluster 46: Basophils - Proteolysis" "Cluster 60: Stomach - Digestion" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." 95 Cytosol "CAB000008: , CAB000030: , HPA001605: " "unprognostic (8.04e-3)" "unprognostic (2.39e-1)" "unprognostic (1.36e-1)" "unprognostic (5.19e-2)" "unprognostic (1.90e-1)" "unprognostic (1.42e-1)" "unprognostic (3.88e-2)" "unprognostic (3.47e-2)" "unprognostic (7.03e-3)" "unprognostic (2.28e-1)" "unprognostic (3.29e-2)" "unprognostic (3.77e-1)" "unprognostic (5.17e-1)" "unprognostic (1.17e-2)" "unprognostic (4.87e-2)" "potential prognostic unfavorable (4.30e-6)" "unprognostic (1.06e-1)" "unprognostic (2.38e-1)" "unprognostic (8.82e-2)" "unprognostic (2.37e-2)" "unprognostic (2.25e-1)" "potential prognostic unfavorable (1.47e-4)" "unprognostic (9.86e-2)" "unprognostic (2.75e-1)" "unprognostic (4.85e-1)" "unprognostic (1.43e-1)" "unprognostic (9.64e-2)" "unprognostic (3.30e-2)" "unprognostic (4.10e-1)" "unprognostic (3.72e-2)" "unprognostic (8.40e-2)" KRT19 "CK19, K19, K1CS, MGC15366" ENSG00000171345 "Keratin 19" P08727 17 41523617-41528308 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 857.0;intestine: 737.0;salivary gland: 772.3;urinary bladder: 729.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 3796.0;Colonocytes: 5383.5;Conjunctival goblet cells: 4806.7;Enterocytes: 7897.8;Esophageal apical cells: 8716.3;Extravillous trophoblasts: 10172.3;Migrating cytotrophoblasts: 4269.9;Respiratory basal cells: 5118.0;Respiratory deuterosomal cells: 3589.8;Respiratory secretory cells: 8050.2;Salivary duct cells: 4002.9;Submucosal glandular cells: 4482.7;Urothelial cells: 5849.1" "Cell type enhanced" "Detected in some" "endothelial cell: 5.4;upper rhombic lip: 10.4;vascular associated smooth muscle cell: 6.9" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 13.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 4070.4" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Liver - Cholangiocytes, Minor Salivary Gland - Minor salivary glandular cells, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Region enriched" "Detected in many" 7 "spinal cord: 62.5" "CAB000031, HPA002465" Enhanced Supported "Intermediate filaments" NA NA 140000000 "Cluster 11: Esophagus - Basic cellular processes" "Cluster 35: Non-specific - DNA binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 124 "Intermediate filaments" "CAB000031: , HPA002465: " "unprognostic (3.95e-1)" "unprognostic (3.36e-1)" "unprognostic (4.25e-1)" "unprognostic (1.70e-1)" "unprognostic (2.03e-1)" "unprognostic (8.89e-2)" "unprognostic (1.97e-1)" "unprognostic (1.04e-1)" "validated prognostic unfavorable (4.67e-4)" "validated prognostic unfavorable (7.42e-4)" "unprognostic (2.68e-1)" "unprognostic (1.93e-1)" "unprognostic (6.24e-2)" "unprognostic (4.19e-3)" "unprognostic (1.46e-1)" "unprognostic (2.33e-1)" "unprognostic (3.48e-1)" "unprognostic (1.79e-2)" "unprognostic (3.11e-1)" "potential prognostic unfavorable (2.68e-5)" "unprognostic (1.27e-1)" "unprognostic (6.11e-2)" "unprognostic (1.16e-1)" "unprognostic (8.29e-2)" "unprognostic (1.97e-1)" "unprognostic (2.48e-2)" "unprognostic (2.29e-1)" "unprognostic (3.51e-2)" "unprognostic (2.35e-1)" KRT2 "KRT2A, KRTE" ENSG00000172867 "Keratin 2" P35908 12 52644558-52652211 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, FDA approved drug targets, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 57 "skin 1: 4421.9" "Cell type enriched" "Detected in some" 49 "Suprabasal keratinocytes: 200.7" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "Skin Cutaneous Melanoma (TCGA): 47.0" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "naive CD4 T-cell: 1.4" "Lineage enriched" "Detected in single" 14 "T-cells: 1.4" "Not detected" "Not detected" "Skin - Keratinocyte (other)" "Group enriched" "Detected in some" 6 "amygdala: 1.7;hippocampal formation: 2.7" "Not detected" "Not detected" "HPA006299, CAB037321" Enhanced Approved "Intermediate filaments,Cytosol" NA NA 3500000000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 37: Skin - Keratinization" "Cluster 24: Non-specific - Unknown function" "Cluster 26: Keratinocytes - Keratinization" 34 "Intermediate filaments, Cytosol" "CAB037321: , HPA006299: " "unprognostic (6.19e-2)" "unprognostic (3.35e-1)" "unprognostic (3.55e-1)" KRT20 "CK20, K20, MGC35423" ENSG00000171431 "Keratin 20" P35900 17 40875889-40885242 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 609.5" "Cell type enhanced" "Detected in some" "Colonocytes: 113.0;Enteric transient amplifying cells: 12.0;Enterocytes: 78.9;Foveolar cells: 12.8;Goblet cells: 24.4;Neuroendocrine cells: 20.6;Urothelial cells: 37.7" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "Bladder Urothelial Carcinoma (TCGA): 47.9;Colon Adenocarcinoma (TCGA): 112.1;Rectum Adenocarcinoma (TCGA): 136.2;Stomach Adenocarcinoma (TCGA): 46.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 41.5;colorectal cancer: 95.3;liver cancer: 50.6" "Colon - Colon enterocytes, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000032, HPA024309, HPA024684, HPA027236" Enhanced Supported "Intermediate filaments,Cytosol" NA NA 38000000 "Cluster 77: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 45 "Intermediate filaments, Cytosol" "CAB000032: , HPA024309: , HPA024684: , HPA027236: " "unprognostic (3.02e-1)" "unprognostic (9.94e-2)" "unprognostic (1.63e-1)" "potential prognostic unfavorable (6.32e-4)" "unprognostic (5.37e-2)" "unprognostic (1.56e-2)" "unprognostic (2.06e-1)" "unprognostic (2.18e-2)" "unprognostic (1.69e-2)" "unprognostic (1.15e-1)" KRT222 "KA21, KRT222P, MGC45562" ENSG00000213424 "Keratin 222" Q8N1A0 17 40654665-40665181 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 11.4;retina: 7.4" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 1.0;Cholangiocytes: 1.3;Epididymal basal cells: 4.5;Epididymal principal cells: 2.3;Medullary thymic epithelial cells: 2.4;Müller glia: 2.0;Ocular epithelial cells: 1.4;Retinal bipolar cells: 2.6" "Cell type enhanced" "Detected in some" "cerebellar inhibitory: 3.1" "Cancer enhanced" "Detected in single" "Kidney Renal Papillary Cell Carcinoma (TCGA): 1.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Rhabdoid: 2.3" "Adipose subcutaneous - Adipose progenitor cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054586, HPA068724, HPA069774" Enhanced Approved "Vesicles,Lipid droplets" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 9 "Vesicles, Lipid droplets" "HPA054586: , HPA068724: , HPA069774: " "unprognostic (4.64e-2)" "unprognostic (4.12e-1)" "unprognostic (2.49e-3)" "unprognostic (9.02e-2)" KRT23 "CK23, DKFZP434G032, HAIK1, K23, MGC26158" ENSG00000108244 "Keratin 23" Q9C075 17 40922700-40937646 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "salivary gland: 134.8;skin 1: 164.8" "Cell type enriched" "Detected in some" 4 "Syncytiotrophoblasts: 590.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 32.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 11.5;testis cancer: 6.6" "Adipose visceral - Neutrophils, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Ductal cells, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (granular), Spleen - Neutrophils_2, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA012050, HPA016959, CAB017091" Approved Approved "Intermediate filaments,Cytosol" NA NA 1200000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 37: Skin - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" "Intermediate filaments" Cytosol "CAB017091: , HPA012050: , HPA016959: " "unprognostic (4.41e-2)" "unprognostic (2.38e-1)" "unprognostic (2.11e-2)" "unprognostic (2.57e-2)" "unprognostic (1.94e-1)" "unprognostic (5.72e-2)" "unprognostic (2.24e-1)" "unprognostic (3.03e-1)" "unprognostic (3.49e-2)" "unprognostic (8.86e-2)" "unprognostic (6.56e-2)" "unprognostic (1.80e-1)" "unprognostic (1.43e-3)" "unprognostic (7.41e-2)" "unprognostic (2.50e-2)" "unprognostic (1.96e-2)" "unprognostic (1.64e-2)" "unprognostic (3.34e-3)" "unprognostic (1.61e-1)" "unprognostic (2.75e-2)" "unprognostic (3.88e-1)" "unprognostic (5.01e-2)" "unprognostic (1.19e-1)" KRT24 "FLJ20261, MGC138169, MGC138173" ENSG00000167916 "Keratin 24" Q2M2I5 17 40697991-40703752 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "cervix: 43.7;esophagus: 167.8;lymphoid tissue: 71.5" "Group enriched" "Detected in some" 8 "Esophageal apical cells: 940.3;Ocular epithelial cells: 385.8" "Cell type enhanced" "Detected in single" "cerebellar inhibitory: 1.6" "Group enriched" "Detected in some" 19 "Bladder Urothelial Carcinoma (TCGA): 19.4;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 14.2;Head and Neck Squamous Cell Carcinoma (TCGA): 20.7;Lung Squamous Cell Carcinoma (TCGA): 6.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 316 "Rhabdoid: 170.8" "Skin - Keratinocyte (other), Stomach - Fibroblasts" "Region enriched" "Detected in single" 10 "cerebellum: 1.0" "Low region specificity" "Detected in many" HPA022978 Uncertain Approved "Intermediate filaments,Cytosol" No NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 5: Rhabdoid - Unknown function" "Cluster 100: Stratified epithelial cells - Barrier functions" 29 "Intermediate filaments, Cytosol" "HPA022978: " "unprognostic (3.78e-1)" "unprognostic (1.32e-1)" "unprognostic (3.11e-2)" "unprognostic (2.49e-2)" "unprognostic (7.84e-1)" "unprognostic (4.99e-2)" "unprognostic (4.94e-3)" KRT25 KRT25A ENSG00000204897 "Keratin 25" Q7Z3Z0 17 40748021-40755331 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 40 "skin 1: 101.5" "Group enriched" "Detected in some" 21 "Early spermatids: 11.5;Late spermatids: 13.1;Undifferentiated spermatogonia: 3.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 106 "Rhabdoid: 61.0" "Skin - Inner root sheath cells, Testis - Late spermatids" "Region enriched" "Detected in some" 7 "cerebellum: 8.6" "Group enriched" "Detected in some" 5 "cerebral cortex: 9.5;hippocampal formation: 6.3" "HPA053977, HPA058943" Enhanced Approved Vesicles NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 5: Rhabdoid - Unknown function" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 22 Vesicles "HPA053977: , HPA058943: " KRT26 KRT25B ENSG00000186393 "Keratin 26" Q7Z3Y9 17 40766238-40772201 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "skin 1: 5.3" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 2.1;Undifferentiated spermatogonia: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 21 "basophil: 2.1;neutrophil: 3.4" "Lineage enriched" "Detected in single" 35 "granulocytes: 3.4" "Not detected" "Not detected" "Skin - Hair cortex cells, Skin - Inner root sheath cells, Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA026890 Enhanced NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 9: Skin - Hair follicle development" "Cluster 25: Non-specific - Transcription" "Cluster 79: Photoreceptor cells - Phototransduction" 18 "HPA026890: " KRT27 KRT25C ENSG00000171446 "Keratin 27" Q7Z3Y8 17 40776808-40782550 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 46 "skin 1: 65.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 3.0;Endometrial secretory cells: 1.6;Epididymal basal cells: 3.4;Medullary thymic epithelial cells: 2.4;Melanocytes: 8.1;Müller glia: 2.4;Ocular epithelial cells: 11.8;Undifferentiated spermatogonia: 3.6" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Uterine Corpus Endometrial Carcinoma (TCGA): 7.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 36 "Rhabdoid: 29.8" "Skin - Inner root sheath cells" "Not detected" "Not detected" "Region enriched" "Detected in all" 5 "hippocampal formation: 105.3" HPA055114 Enhanced NA NA 470000000 "Cluster 9: Skin - Hair follicle development" "Cluster 5: Rhabdoid - Unknown function" "Cluster 100: Stratified epithelial cells - Barrier functions" 124 "HPA055114: " "unprognostic (2.28e-1)" "unprognostic (1.99e-1)" "unprognostic (6.63e-1)" KRT28 KRT25D ENSG00000173908 "Keratin 28" Q7Z3Y7 17 40792196-40799959 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 14 "skin 1: 10.6" "Group enriched" "Detected in some" 4 "Retinal ganglion cells: 3.9;Undifferentiated spermatogonia: 2.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 1.2;Uterine Corpus Endometrial Carcinoma (TCGA): 1.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 815 "Rhabdoid: 81.4" "Skin - Inner root sheath cells" "Region enriched" "Detected in single" 6 "cerebellum: 3.2" "Low region specificity" "Detected in all" HPA066890 Enhanced NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 5: Rhabdoid - Unknown function" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 15 "HPA066890: " KRT3 "CK3, K3" ENSG00000186442 "Keratin 3" P12035 12 52789685-52796117 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "esophagus: 2.9;salivary gland: 10.0" "Group enriched" "Detected in some" 74 "Ocular epithelial cells: 1216.9;Suprabasal keratinocytes: 506.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Head and Neck Squamous Cell Carcinoma (TCGA): 2.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lymphoma: 2.0" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in many" NA NA 280000000 "Cluster 11: Esophagus - Basic cellular processes" "Cluster 50: Lymphoma - Unknown function" "Cluster 100: Stratified epithelial cells - Barrier functions" 45 "unprognostic (4.00e-3)" "unprognostic (3.26e-1)" KRT31 "Ha-1, KRTHA1" ENSG00000094796 "Keratin 31" Q15323 17 41393721-41397608 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "skin 1: 257.3" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 7.9;Brain excitatory neurons: 5.3;Endometrial luminal cells: 3.2;Esophageal apical cells: 1.2;Esophageal suprabasal cells: 1.1;Suprabasal keratinocytes: 1.4" "Group enriched" "Detected in some" 5 "thalamic excitatory: 7.3;upper rhombic lip: 17.1" "Cancer enriched" "Detected in single" 8 "Lung Squamous Cell Carcinoma (TCGA): 6.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skeletal muscle - Skeletal myocytes, Skin - Hair cortex cells, Skin - Inner root sheath cells" "HPA049550, HPA055194" Enhanced Approved "Cytosol,Equatorial segment,Mid piece,Principal piece,End piece" NA NA 65000000 "Cluster 9: Skin - Hair follicle development" "Cluster 38: Sub-cortical - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 324 "Cytosol, Principal piece, End piece" "Equatorial segment, Mid piece" "HPA049550: , HPA055194: " "unprognostic (1.38e-2)" "unprognostic (2.73e-1)" KRT32 "Ha-2, KRTHA2" ENSG00000108759 "Keratin 32" Q14532 17 41459513-41467386 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "esophagus: 5.5;skin 1: 16.6" "Cell type enriched" "Detected in some" 8 "Esophageal basal cells: 37.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "colorectal cancer: 1.1" "Skin - Hair cortex cells, Skin - Inner root sheath cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 38000000 "Cluster 58: Skin - Keratinization" "Cluster 27: Breast cancer - Unknown function" "Cluster 26: Keratinocytes - Keratinization" 4 "unprognostic (3.56e-1)" KRT33A "Ha-3I, Krt1-3, KRTHA3A" ENSG00000006059 "Keratin 33A" O76009 17 41346092-41350828 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "skin 1: 42.6" "Group enriched" "Detected in some" 5 "Early spermatids: 1.2;Late spermatids: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Skin - Inner root sheath cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA055194 Supported Approved "Cytosol,Equatorial segment,Mid piece,Principal piece,End piece" NA NA 17000000 "Cluster 37: Skin - Keratinization" "Cluster 11: Neuronal - Sensory perception" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" "Cytosol, Principal piece, End piece" "Equatorial segment, Mid piece" "HPA055194: " KRT33B "Ha-3II, KRTHA3B" ENSG00000131738 "Keratin 33B" Q14525 17 41363498-41369813 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 56 "skin 1: 74.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Minor Salivary Gland - Minor salivary gland basal cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Testis - Late spermatids" HPA055194 Supported Approved "Cytosol,Equatorial segment,Mid piece,Principal piece,End piece" NA NA 58000000 "Cluster 9: Skin - Hair follicle development" "Cluster 64: Connective tissue cells - ECM organization" 81 "Cytosol, Principal piece, End piece" "Equatorial segment, Mid piece" "HPA055194: " KRT34 "Ha-4, KRTHA4" ENSG00000131737 "Keratin 34" O76011 17 41377669-41382306 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 22 "skin 1: 64.6" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Head and Neck Squamous Cell Carcinoma (TCGA): 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 7.1" "Skin - Hair cortex cells, Testis - Late spermatids" "Not detected" "Not detected" "HPA055194, HPA072208" Enhanced Approved "Cytosol,Equatorial segment,Mid piece,Principal piece,End piece" NA NA 17000000 "Cluster 9: Skin - Hair follicle development" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 211 "Cytosol, Principal piece, End piece" "Equatorial segment, Mid piece" "HPA055194: , HPA072208: " "unprognostic (2.72e-2)" KRT35 "Ha-5, KRTHA5" ENSG00000197079 "Keratin 35" Q92764 17 41476710-41481151 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 32 "skin 1: 55.3" "Cell type enriched" "Detected in single" 7 "Epididymal clear cells: 4.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Skin - Inner root sheath cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA025750, HPA078713" Enhanced Approved "Intermediate filaments" NA NA 36000000 "Cluster 9: Skin - Hair follicle development" "Cluster 32: Non-specific - Cell proliferation" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 69 "Intermediate filaments" "HPA025750: , HPA078713: " KRT36 KRTHA6 ENSG00000126337 "Keratin 36" O76013 17 41486136-41492546 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 3.1;skin 1: 1.7" "Group enriched" "Detected in some" 26 "Oocytes: 363.8;Suprabasal keratinocytes: 170.6" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Head and Neck Squamous Cell Carcinoma (TCGA): 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "cervical cancer: 1.8" "Skin - Hair cortex cells, Skin - Inner root sheath cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 32000000 "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" "unprognostic (8.14e-2)" "unprognostic (9.95e-2)" KRT37 KRTHA7 ENSG00000108417 "Keratin 37" O76014 17 41420547-41424585 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 16 "skin 1: 6.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "colorectal cancer: 1.0" "Skin - Hair cortex cells, Skin - Inner root sheath cells" NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 36 "unprognostic (2.78e-3)" KRT38 KRTHA8 ENSG00000171360 "Keratin 38" O76015 17 41436154-41440983 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 18 "skin 1: 16.2" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Head and Neck Squamous Cell Carcinoma (TCGA): 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Skin - Inner root sheath cells" NA NA 37000000 "Cluster 9: Skin - Hair follicle development" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 96 "unprognostic (1.42e-1)" KRT39 KA35 ENSG00000196859 "Keratin 39" Q6A163 17 40958417-40966948 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 5 "skin 1: 4.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Skin - Inner root sheath cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA057307 Approved "Mid piece,Principal piece,Annulus" NA NA 270000 "Cluster 9: Skin - Hair follicle development" "Cluster 32: Non-specific - Cell proliferation" 28 Annulus "Mid piece, Principal piece" "HPA057307: " KRT4 "CK4, CYK4, K4" ENSG00000170477 "Keratin 4" P19013 12 52806549-52814116 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "esophagus: 18547.1" "Group enriched" "Detected in some" 4 "Esophageal apical cells: 74822.7;Esophageal suprabasal cells: 30263.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 230.8;Head and Neck Squamous Cell Carcinoma (TCGA): 328.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "cervical cancer: 1151.1;Gallbladder cancer: 1422.0" "Prostate - Urothelial cells, Skin - Sebaceous gland cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB002154, HPA034881" Enhanced Supported "Intermediate filaments" NA NA 170000000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 28 "Intermediate filaments" "CAB002154: , HPA034881: " "unprognostic (4.16e-1)" "unprognostic (4.44e-1)" "unprognostic (9.03e-2)" "potential prognostic favorable (6.05e-5)" "unprognostic (9.85e-2)" "unprognostic (2.10e-1)" "unprognostic (4.62e-2)" "unprognostic (5.53e-2)" "unprognostic (6.13e-2)" "unprognostic (2.06e-1)" "potential prognostic unfavorable (4.38e-4)" "unprognostic (2.49e-1)" "unprognostic (3.18e-3)" "unprognostic (6.94e-2)" "unprognostic (5.52e-2)" "unprognostic (5.70e-1)" "unprognostic (1.02e-1)" "unprognostic (8.98e-1)" "unprognostic (2.62e-1)" KRT40 "FLJ36600, KA36" ENSG00000204889 "Keratin 40" Q6A162 17 40977715-40987135 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "pituitary gland: 2.4;retina: 2.7;skin 1: 2.1" "Cell type enhanced" "Detected in some" "Müller glia: 1.4;Neuroendocrine cells: 1.4" "Cell type enhanced" "Detected in single" "cerebellar inhibitory: 1.1" "Cancer enriched" "Detected in single" 9 "Rectum Adenocarcinoma (TCGA): 6.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 11.2;Gastric cancer: 4.8" "Lung - Respiratory ciliated cells, Pituitary gland - Gonadotropes, Skin - Hair cortex cells, Skin - Inner root sheath cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA075961 Supported NA NA 1100000 "Cluster 42: Retina - Visual perception" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" 312 "HPA075961: " "unprognostic (1.11e-1)" KRT5 "CK-5, EBS2, KRT5A" ENSG00000186081 "Keratin 5" P13647 12 52514575-52520530 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "cervix: 2249.7;esophagus: 6496.3;skin 1: 5566.5;vagina: 2417.1" "Group enriched" "Detected in many" 5 "Basal keratinocytes: 7750.0;Esophageal basal cells: 12161.5;Esophageal suprabasal cells: 8165.7;Ocular epithelial cells: 6624.3;Suprabasal keratinocytes: 3358.8" "Cell type enriched" "Detected in single" 24 "choroid plexus epithelial cell: 14.2" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 5619.7;Head and Neck Squamous Cell Carcinoma (TCGA): 10039.4" "Region enriched" "Detected in many" 34 "choroid plexus: 129.6" "Immune cell enriched" "Detected in single" 327 "plasmacytoid DC: 32.6" "Lineage enriched" "Detected in single" 327 "dendritic cells: 32.6" "Cancer enhanced" "Detected in many" "cervical cancer: 3091.5;Esophageal cancer: 1910.0;head and neck cancer: 3757.4" "Adipose visceral - Mesothelial cells, Breast - Breast myoepithelial cells, Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Prostate basal glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB000027, CAB000129, HPA059479, CAB080101" Enhanced Approved "Intermediate filaments" NA NA 1300000000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 35 "Intermediate filaments" "CAB000027: , CAB000129: , CAB080101: , HPA059479: " "unprognostic (4.14e-3)" "potential prognostic favorable (1.32e-4)" "unprognostic (1.46e-1)" "unprognostic (4.11e-2)" "unprognostic (1.93e-2)" "unprognostic (2.49e-2)" "unprognostic (8.76e-2)" "unprognostic (1.96e-1)" "unprognostic (2.00e-1)" "unprognostic (1.30e-1)" "unprognostic (1.05e-1)" "unprognostic (1.19e-1)" "unprognostic (8.13e-2)" "unprognostic (2.82e-2)" "unprognostic (8.69e-2)" "unprognostic (7.89e-2)" "unprognostic (1.26e-1)" "unprognostic (2.29e-2)" "potential prognostic unfavorable (4.11e-4)" "unprognostic (1.39e-1)" "unprognostic (4.13e-2)" "unprognostic (1.67e-1)" "unprognostic (8.29e-2)" "unprognostic (6.51e-2)" "unprognostic (1.15e-1)" "unprognostic (1.69e-2)" KRT6A "CK6C, CK6D, K6C, K6D, KRT6C, KRT6D" ENSG00000205420 "Keratin 6A" P02538 12 52487176-52493257 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Allergen, Disease variant, Ectodermal dysplasia, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "cervix: 5174.7;esophagus: 7111.4;vagina: 4763.0" "Group enriched" "Detected in many" 4 "Esophageal apical cells: 41303.6;Esophageal suprabasal cells: 27326.1;Suprabasal keratinocytes: 10474.8" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 10248.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 2730.0;head and neck cancer: 1413.8" "Skin - Outer root sheath cells" "HPA045697, HPA061168" Supported Enhanced "Intermediate filaments" NA NA 1400000000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 46 "Intermediate filaments" "HPA045697: , HPA061168: " "unprognostic (1.99e-1)" "unprognostic (6.10e-3)" "unprognostic (9.62e-2)" "unprognostic (2.56e-1)" "unprognostic (2.93e-2)" "unprognostic (1.41e-2)" "unprognostic (2.30e-1)" "unprognostic (4.77e-1)" "potential prognostic unfavorable (6.90e-8)" "unprognostic (3.05e-1)" "unprognostic (2.94e-2)" "unprognostic (2.83e-2)" "unprognostic (1.72e-2)" "unprognostic (2.79e-1)" "unprognostic (1.00e-3)" "potential prognostic unfavorable (4.05e-4)" "unprognostic (7.47e-2)" "unprognostic (1.87e-1)" "unprognostic (1.49e-1)" "unprognostic (2.44e-1)" "unprognostic (1.42e-1)" "unprognostic (8.64e-2)" "unprognostic (1.01e-1)" "unprognostic (4.98e-2)" KRT6B KRTL1 ENSG00000185479 "Keratin 6B" P04259 12 52446651-52452146 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Ectodermal dysplasia, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 341.3;esophagus: 923.4;skin 1: 266.2" "Group enriched" "Detected in some" 5 "Esophageal apical cells: 6596.3;Esophageal suprabasal cells: 6596.2" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "Head and Neck Squamous Cell Carcinoma (TCGA): 3497.7;Skin Cutaneous Melanoma (TCGA): 934.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "head and neck cancer: 104.9" "Skin - Outer root sheath cells" "CAB000130, HPA045697, HPA061168" Supported Approved "Intermediate filaments" NA NA 1600000000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 30 "Intermediate filaments" "CAB000130: , HPA045697: , HPA061168: " "unprognostic (1.61e-1)" "unprognostic (2.67e-3)" "unprognostic (2.80e-1)" "unprognostic (1.62e-1)" "unprognostic (1.77e-1)" "unprognostic (1.55e-1)" "unprognostic (1.80e-1)" "unprognostic (6.48e-2)" "potential prognostic unfavorable (1.15e-6)" "unprognostic (1.42e-2)" "unprognostic (1.38e-1)" "unprognostic (4.37e-2)" "potential prognostic unfavorable (4.09e-4)" "unprognostic (6.78e-2)" "unprognostic (1.66e-1)" "unprognostic (1.75e-1)" "unprognostic (1.57e-1)" "unprognostic (1.89e-1)" "unprognostic (1.28e-1)" "unprognostic (1.25e-1)" KRT6C KRT6E ENSG00000170465 "Keratin 6C" P48668 12 52468516-52473805 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 482.5;esophagus: 792.4;vagina: 322.2" "Group enriched" "Detected in some" 13 "Esophageal apical cells: 5611.0;Esophageal suprabasal cells: 5141.4;Suprabasal keratinocytes: 1605.7" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "Head and Neck Squamous Cell Carcinoma (TCGA): 1854.2;Skin Cutaneous Melanoma (TCGA): 583.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 33.2;head and neck cancer: 14.4" "Skin - Hair cortex cells, Skin - Outer root sheath cells" "HPA045697, HPA061168" Supported Approved "Intermediate filaments" NA NA 1400000000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 29 "Intermediate filaments" "HPA045697: , HPA061168: " "unprognostic (2.19e-1)" "unprognostic (3.79e-2)" "unprognostic (3.45e-1)" "unprognostic (1.00e-1)" "unprognostic (8.59e-2)" "unprognostic (3.34e-1)" "potential prognostic unfavorable (1.76e-7)" "unprognostic (5.41e-2)" "unprognostic (6.42e-2)" "unprognostic (2.47e-2)" "potential prognostic unfavorable (7.78e-4)" "unprognostic (1.88e-1)" "unprognostic (1.83e-1)" "unprognostic (4.96e-1)" KRT7 "CK-7, CK7, K2C7, K7, SCL" ENSG00000135480 "Keratin 7" P08729 12 52232520-52252186 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 341.9;salivary gland: 952.4;thyroid gland: 405.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 7673.7;Alveolar cells type 2: 1622.9;Cytotrophoblasts: 1975.3;Epididymal clear cells: 1586.1;Extravillous trophoblasts: 5987.0;Migrating cytotrophoblasts: 2713.5;Salivary acinar cells: 1611.4;Salivary duct cells: 1683.3;Salivary ionocytes: 2130.1;Submucosal glandular cells: 1541.1;Syncytiotrophoblasts: 1377.9;Transitional alveolar cells: 1574.9;Urothelial cells: 1483.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 2593.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Liver - Cholangiocytes, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Ductal cells, Skin - Eccrine sweat gland cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000028, HPA007272, HPA007315, CAB079970, CAB080115" Enhanced Supported "Intermediate filaments,Cytosol" NA NA 130000000 "Cluster 82: Salivary gland - Secretion" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 9 "Intermediate filaments, Cytosol" "CAB000028: , CAB079970: , CAB080115: , HPA007272: , HPA007315: " "unprognostic (1.15e-1)" "unprognostic (3.68e-3)" "unprognostic (7.15e-2)" "unprognostic (1.47e-1)" "unprognostic (1.72e-1)" "unprognostic (9.46e-2)" "unprognostic (1.29e-1)" "unprognostic (3.39e-2)" "unprognostic (5.96e-2)" "unprognostic (4.48e-2)" "potential prognostic favorable (4.28e-7)" "unprognostic (1.52e-1)" "unprognostic (2.07e-2)" "potential prognostic unfavorable (2.37e-6)" "unprognostic (8.79e-2)" "unprognostic (7.59e-2)" "unprognostic (4.07e-3)" "potential prognostic unfavorable (3.20e-4)" "unprognostic (3.96e-3)" "validated prognostic unfavorable (4.87e-5)" "validated prognostic unfavorable (4.51e-4)" "unprognostic (2.70e-2)" "unprognostic (8.53e-2)" "unprognostic (1.32e-1)" "unprognostic (2.12e-1)" "unprognostic (2.68e-1)" "unprognostic (3.74e-2)" "unprognostic (5.60e-2)" "unprognostic (3.53e-2)" KRT71 "K6IRS1, KRT6IRS, KRT6IRS1" ENSG00000139648 "Keratin 71" Q3SY84 12 52543909-52553145 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 22 "skin 1: 91.0" "Cell type enriched" "Detected in single" 17 "Epididymal principal cells: 7.9" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "Uterine Corpus Endometrial Carcinoma (TCGA): 4.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Inner root sheath cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA049404 Enhanced NA NA 60000000 "Cluster 9: Skin - Hair follicle development" "Cluster 65: Non-specific - Unknown function" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" 23 "HPA049404: " "unprognostic (5.37e-1)" KRT72 "K6irs, K6IRS2, KRT6, KRT6IRS2" ENSG00000170486 "Keratin 72" Q14CN4 12 52585589-52601538 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "skin 1: 10.7;testis: 22.9" "Group enriched" "Detected in some" 4 "Late primary spermatocytes: 100.8;Late spermatids: 111.4" "Cell type enriched" "Detected in single" 37 "leukocyte: 3.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 17 "Leukemia: 2.4" "Lung - NK-cells (Lung), Skin - Hair cortex cells, Skin - Inner root sheath cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA065523 Enhanced NA NA "Cluster 47: Testis - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 22 "HPA065523: " KRT73 "K6IRS3, KRT6IRS3" ENSG00000186049 "Keratin 73" Q86Y46 12 52607570-52618559 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skin 1: 16.7" "Cell type enhanced" "Detected in some" "Early spermatids: 1.4;Late spermatids: 1.2;NK-cells: 2.0" "Cell type enriched" "Detected in single" 17 "leukocyte: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "naive CD4 T-cell: 8.9;naive CD8 T-cell: 3.1" "Lineage enriched" "Detected in single" 13 "T-cells: 8.9" "Cancer enriched" "Detected in single" 10 "Leukemia: 1.7" "Lung - NK-cells (Lung), Skin - Inner root sheath cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA044031 Enhanced NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 37: Skin - Keratinization" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" 2 "HPA044031: " KRT74 "K6IRS4, KRT5C, KRT6IRS4" ENSG00000170484 "Keratin 74" Q7RTS7 12 52565782-52573843 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Ectodermal dysplasia, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "epididymis: 5.3;skin 1: 14.6" "Group enriched" "Detected in some" 9 "Epididymal principal cells: 2.5;Late spermatids: 7.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "Gallbladder cancer: 3.6" "Skin - Inner root sheath cells" "Not detected" "Not detected" "HPA040655, HPA048596" Enhanced Approved "Nucleoli,Intermediate filaments,Cytosol" NA NA 88000000 "Cluster 9: Skin - Hair follicle development" "Cluster 32: Non-specific - Cell proliferation" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 16 "Intermediate filaments" "Nucleoli, Cytosol" "HPA040655: , HPA048596: " KRT75 K6HF ENSG00000170454 "Keratin 75" O95678 12 52424070-52434371 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "skin 1: 27.4" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 3.4;Early spermatids: 2.2;Esophageal basal cells: 1.5;Late spermatids: 4.4;Suprabasal keratinocytes: 3.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 57.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 7.4" "Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA019367, HPA076201" Enhanced Approved "Plasma membrane,Cytosol" NA NA 350000000 "Cluster 9: Skin - Hair follicle development" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 130 Cytosol "Plasma membrane" "HPA019367: , HPA076201: " "unprognostic (8.52e-2)" "unprognostic (9.90e-2)" "unprognostic (1.34e-2)" "unprognostic (9.78e-2)" "unprognostic (2.66e-2)" "unprognostic (2.01e-2)" "unprognostic (1.59e-3)" "unprognostic (4.05e-3)" "unprognostic (1.95e-1)" "unprognostic (1.26e-3)" "unprognostic (6.10e-2)" "unprognostic (3.51e-2)" "unprognostic (5.65e-2)" "unprognostic (2.71e-1)" "unprognostic (1.42e-1)" KRT76 "HUMCYT2A, KRT2B, KRT2P" ENSG00000185069 "Keratin 76" Q01546 12 52768155-52777345 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "lymphoid tissue: 2.4;salivary gland: 3.8" "Cell type enriched" "Detected in some" 22 "Suprabasal keratinocytes: 445.5" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "Head and Neck Squamous Cell Carcinoma (TCGA): 2.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA019656, HPA019696" Approved NA NA 270000000 "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 41 "HPA019656: , HPA019696: " "unprognostic (9.17e-2)" KRT77 KRT1B ENSG00000189182 "Keratin 77" Q7Z794 12 52689626-52703524 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "skin 1: 262.0" "Cell type enriched" "Detected in some" 10 "Suprabasal keratinocytes: 17.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA045934 Enhanced Approved "Nuclear membrane,Plasma membrane" NA NA 400000000 "Cluster 37: Skin - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 26: Keratinocytes - Keratinization" 10 "Nuclear membrane, Plasma membrane" "HPA045934: " "unprognostic (7.95e-2)" "unprognostic (1.03e-1)" "unprognostic (1.26e-1)" "unprognostic (1.82e-2)" "unprognostic (2.78e-1)" "unprognostic (2.86e-1)" KRT78 K5B ENSG00000170423 "Keratin 78" Q8N1N4 12 52837804-52849092 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "esophagus: 880.3" "Cell type enriched" "Detected in some" 30 "Esophageal apical cells: 7863.2" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 15.6;Head and Neck Squamous Cell Carcinoma (TCGA): 42.3;Skin Cutaneous Melanoma (TCGA): 16.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA039724 Enhanced NA NA 100000000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 18 "HPA039724: " "unprognostic (3.02e-1)" "unprognostic (1.26e-1)" "unprognostic (3.38e-2)" "unprognostic (4.94e-2)" "unprognostic (1.51e-1)" "unprognostic (2.07e-1)" "unprognostic (4.57e-3)" "unprognostic (1.07e-1)" "unprognostic (1.34e-1)" KRT79 "K6L, KRT6L" ENSG00000185640 "Keratin 79" Q5XKE5 12 52821408-52834311 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "skin 1: 67.0" "Group enriched" "Detected in some" 4 "Esophageal apical cells: 3.6;Late spermatids: 3.9" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder Urothelial Carcinoma (TCGA): 8.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 4.7;Sarcoma: 2.0" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Skin - Sebaceous gland cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA059347 Enhanced NA NA 320000000 "Cluster 9: Skin - Hair follicle development" "Cluster 49: HMC-1 - Innate immune response" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 27 "HPA059347: " "unprognostic (1.22e-1)" "unprognostic (1.12e-2)" "unprognostic (1.02e-2)" "unprognostic (1.81e-1)" "unprognostic (2.98e-1)" "unprognostic (2.13e-1)" KRT8 "CARD2, CK-8, CK8, CYK8, K2C8, K8, KO" ENSG00000170421 "Keratin 8" P05787 12 52897187-52949954 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1281.6;stomach 1: 768.4" "Cell type enhanced" "Detected in many" "Colonocytes: 8807.1;Enteric transient amplifying cells: 3101.5;Enterocytes: 5865.2;Extravillous trophoblasts: 6860.0;Goblet cells: 3744.4;Migrating cytotrophoblasts: 5080.1;Pancreatic duct cells: 2480.3;Syncytiotrophoblasts: 6235.5" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 8.5;lower rhombic lip: 15.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 1.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Kidney - Macrophages, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Corticotropes, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 12 "spinal cord: 64.6" "CAB000131, CAB001696, HPA049866" Enhanced Supported "Intermediate filaments" NA NA 280000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 77: Intestine - Digestion" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 74 "Intermediate filaments" "CAB000131: , CAB001696: , HPA049866: " "unprognostic (2.43e-1)" "unprognostic (5.03e-2)" "unprognostic (1.64e-1)" "unprognostic (3.57e-1)" "unprognostic (9.50e-2)" "unprognostic (2.18e-2)" "unprognostic (1.09e-2)" "unprognostic (2.63e-2)" "unprognostic (5.24e-3)" "unprognostic (4.90e-1)" "unprognostic (2.29e-1)" "unprognostic (2.14e-1)" "unprognostic (1.14e-1)" "unprognostic (1.12e-2)" "unprognostic (1.10e-2)" "potential prognostic unfavorable (7.98e-5)" "unprognostic (6.46e-3)" "unprognostic (2.82e-1)" "unprognostic (4.51e-2)" "unprognostic (4.32e-2)" "unprognostic (2.12e-1)" "potential prognostic unfavorable (5.69e-5)" "unprognostic (1.25e-1)" "unprognostic (1.63e-1)" "unprognostic (1.15e-1)" "unprognostic (4.54e-2)" "unprognostic (2.38e-1)" "unprognostic (5.66e-2)" "unprognostic (2.64e-1)" "unprognostic (6.14e-2)" "unprognostic (1.09e-2)" KRT80 KB20 ENSG00000167767 "Keratin 80" Q6KB66 12 52168996-52192014 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "skin 1: 211.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 101.4;Breast lactating cells: 55.3;Breast secretory cells: 46.3;Endometrial ciliated cells: 50.8;Endometrial glandular cells: 48.0;Epididymal efferent duct ciliated cells: 52.0;Esophageal apical cells: 341.8;Pancreatic duct cells: 78.4;Salivary duct cells: 86.8;Suprabasal keratinocytes: 44.7;Syncytiotrophoblasts: 69.8;Urothelial cells: 67.0" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Liver - Cholangiocytes, Pancreas - Ductal cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA077836, HPA077918" Enhanced "Intermediate filaments" No No 63000000 "Cluster 58: Skin - Keratinization" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 4 "Intermediate filaments" "HPA077836: , HPA077918: " "unprognostic (3.45e-1)" "unprognostic (4.18e-3)" "unprognostic (9.24e-2)" "unprognostic (6.24e-2)" "unprognostic (1.54e-1)" "unprognostic (2.08e-1)" "unprognostic (9.83e-2)" "unprognostic (2.28e-1)" "unprognostic (3.13e-3)" "unprognostic (9.77e-2)" "unprognostic (2.26e-2)" "unprognostic (5.33e-3)" "unprognostic (9.83e-2)" "potential prognostic unfavorable (1.52e-5)" "unprognostic (2.92e-2)" "unprognostic (1.46e-1)" "unprognostic (1.87e-2)" "unprognostic (1.22e-2)" "unprognostic (7.29e-2)" "unprognostic (7.52e-3)" "unprognostic (2.58e-2)" "unprognostic (9.53e-2)" "unprognostic (8.34e-2)" "unprognostic (6.19e-2)" "unprognostic (3.30e-2)" "unprognostic (1.15e-1)" "unprognostic (2.63e-1)" "unprognostic (3.53e-1)" "unprognostic (2.46e-2)" KRT81 "Hb-1, KRTHB1" ENSG00000205426 "Keratin 81" Q14533 12 52285913-52291534 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 33 "skin 1: 131.0" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 223.0;Breast secretory cells: 196.6;Conjunctival goblet cells: 38.8;Innate lymphoid cells: 53.6;NK-cells: 59.7;Respiratory deuterosomal cells: 27.0;Submucosal glandular cells: 27.2" "Group enriched" "Detected in many" 4 "Breast Invasive Carcinoma (TCGA): 68.9;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 76.7;Lung Adenocarcinoma (TCGA): 20.0" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in some" 49 "basophil: 171.6" "Lineage enriched" "Detected in many" 49 "granulocytes: 171.6" "Cancer enhanced" "Detected in many" "breast cancer: 443.2" "Skin - Hair cortex cells, Skin - Inner root sheath cells" HPA049778 Supported NA NA 38000000 "Cluster 46: Basophils - Proteolysis" "Cluster 9: Skin - Hair follicle development" "Cluster 1: Neurons - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 28 "HPA049778: " "unprognostic (3.76e-2)" "unprognostic (5.60e-3)" "unprognostic (5.26e-2)" "unprognostic (4.84e-2)" "unprognostic (1.11e-1)" "potential prognostic unfavorable (3.37e-4)" "unprognostic (7.90e-2)" "unprognostic (4.43e-1)" "unprognostic (1.74e-2)" "unprognostic (2.30e-1)" "unprognostic (8.52e-2)" "unprognostic (8.57e-3)" "unprognostic (7.64e-2)" "unprognostic (7.74e-2)" "unprognostic (1.03e-1)" KRT82 "Hb-2, KRTHB2" ENSG00000161850 "Keratin 82" Q9NSB4 12 52393931-52406335 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 36 "skin 1: 11.7" "Group enriched" "Detected in some" 4 "Early spermatids: 2.3;Late spermatids: 2.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Skin - Inner root sheath cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA058715, HPA067230" Enhanced NA NA 4600000 "Cluster 9: Skin - Hair follicle development" "Cluster 70: DU4475 - Unknown function" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 13 "HPA058715: , HPA067230: " KRT83 "Hb-3, KRTHB3" ENSG00000170523 "Keratin 83" P78385 12 52314301-52321398 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 30 "skin 1: 60.5" "Cell type enhanced" "Detected in some" "Breast secretory cells: 1.2;Innate lymphoid cells: 2.0" "Cell type enhanced" "Detected in single" "oligodendrocyte: 1.2" "Cancer enhanced" "Detected in some" "Thyroid Carcinoma (TCGA): 3.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "breast cancer: 1.7" "Minor Salivary Gland - Minor salivary glandular cells, Skin - Hair cortex cells, Skin - Inner root sheath cells" HPA049778 Supported NA NA 38000000 "Cluster 9: Skin - Hair follicle development" "Cluster 30: White matter - Myelination" "Cluster 7: Liver cancer - Metabolism" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 37 "HPA049778: " "unprognostic (4.29e-2)" "unprognostic (4.43e-3)" KRT84 "Hb-4, KRTHB4" ENSG00000161849 "Keratin 84" Q9NSB2 12 52377812-52385652 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "lymphoid tissue: 1.4;skin 1: 1.7" "Cell type enriched" "Detected in single" 15 "Suprabasal keratinocytes: 8.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Head and Neck Squamous Cell Carcinoma (TCGA): 1.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "cervical cancer: 8.8;head and neck cancer: 6.3" "Pituitary gland - Corticotropes, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA039714 Supported NA NA 42000000 "Cluster 49: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" "HPA039714: " "unprognostic (1.93e-2)" KRT85 "Hb-5, KRTHB5" ENSG00000135443 "Keratin 85" P78386 12 52360006-52367481 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Ectodermal dysplasia, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 52 "skin 1: 158.6" "Cell type enriched" "Detected in some" 4 "Late spermatids: 31.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA049778 Supported NA NA 29000000 "Cluster 9: Skin - Hair follicle development" "Cluster 27: Breast cancer - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 30 "HPA049778: " "potential prognostic favorable (1.56e-4)" KRT86 "Hb6, KRTHB6, MNX" ENSG00000170442 "Keratin 86" O43790 12 52249300-52309163 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 35 "skin 1: 136.3" "Cell type enhanced" "Detected in many" "Breast secretory cells: 45.2;Conjunctival goblet cells: 45.6;Early spermatids: 56.3;Endometrial glandular cells: 67.7;Endometrial luminal cells: 73.4;Epididymal basal cells: 113.6;Epididymal clear cells: 87.8;Innate lymphoid cells: 61.1;NK-cells: 71.6;Salivary acinar cells: 123.7;Salivary basal cells: 131.2;Salivary myoepithelial cells: 78.2;Urothelial cells: 52.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 9 "basophil: 87.8" "Lineage enriched" "Detected in many" 9 "granulocytes: 87.8" "Group enriched" "Detected in many" 5 "breast cancer: 101.1;pancreatic cancer: 27.5" "Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Ductal cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "HPA039798, HPA049778" Supported Approved Cytosol NA NA 35000000 "Cluster 41: Basophils - Unknown function" "Cluster 9: Skin - Hair follicle development" "Cluster 14: Neurons - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 44 Cytosol "HPA039798: , HPA049778: " "unprognostic (9.43e-2)" "unprognostic (2.38e-2)" "unprognostic (1.62e-1)" "unprognostic (2.18e-1)" "unprognostic (4.93e-2)" "unprognostic (6.45e-2)" "unprognostic (7.90e-2)" "unprognostic (1.38e-1)" "unprognostic (1.18e-2)" "unprognostic (8.49e-2)" "unprognostic (6.28e-3)" "unprognostic (1.74e-1)" "unprognostic (1.28e-1)" "unprognostic (1.85e-2)" "unprognostic (2.53e-1)" "unprognostic (1.17e-2)" "unprognostic (7.22e-2)" "unprognostic (2.97e-1)" KRT9 "CK-9, EPPK, K9" ENSG00000171403 "Keratin 9" P35527 17 41565836-41572059 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 11.3" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 10.6;Basal keratinocytes: 2.5;Breast myoepithelial cells: 7.7;Extravillous trophoblasts: 3.3;Salivary myoepithelial cells: 1.9" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "Skin Cutaneous Melanoma (TCGA): 46.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 4.2;head and neck cancer: 3.0" "Adrenal gland - Adrenal medulla cells, Breast - Breast myoepithelial cells, Minor Salivary Gland - Minor salivary gland basal cells" "Region enhanced" "Detected in many" "basal ganglia: 25.1" "HPA007261, CAB037322" Supported NA NA 7900000000 "Cluster 80: Thymus - Adaptive immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 26: Keratinocytes - Keratinization" 5 "CAB037322: , HPA007261: " "unprognostic (1.60e-1)" "unprognostic (3.80e-3)" "unprognostic (1.06e-1)" "unprognostic (1.27e-1)" "unprognostic (1.36e-1)" KRTAP1-1 "HB2A, KAP1.1, KAP1.1A, KAP1.1B" ENSG00000188581 "Keratin associated protein 1-1" Q07627 17 41040541-41041450 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 76 "skin 1: 73.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells" NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 64: Connective tissue cells - ECM organization" 150 KRTAP1-3 KAP1.3 ENSG00000221880 "Keratin associated protein 1-3" Q8IUG1 17 41033884-41034874 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 98 "skin 1: 88.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells" NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 10: Ciliated cells - Ion channel activity" 140 KRTAP1-4 KAP1.4 ENSG00000204887 "Keratin associated protein 1-4" P0C5Y4 17 41029351-41030195 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 15 "skin 1: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells" "Low region specificity" "Detected in some" NA NA "Cluster 9: Skin - Hair follicle development" KRTAP1-5 KAP1.5 ENSG00000221852 "Keratin associated protein 1-5" Q9BYS1 17 41026026-41027208 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 64 "skin 1: 71.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 2.0;Sarcoma: 3.2" "Skin - Hair cortex cells" "Not detected" "Not detected" NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 64: Connective tissue cells - ECM organization" 32 KRTAP10-1 "KAP10.1, KAP18.1, KRTAP18-1" ENSG00000215455 "Keratin associated protein 10-1" P60331 21 44538981-44540195 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 79 "skin 1: 9.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Skin - Inner root sheath cells" NA NA "Cluster 9: Skin - Hair follicle development" 8 KRTAP10-10 "KAP10.10, KAP18.10, KRTAP18-10" ENSG00000221859 "Keratin associated protein 10-10" P60014 21 44637356-44638455 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 70 "skin 1: 17.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Skin - Inner root sheath cells" NA NA 110000 "Cluster 9: Skin - Hair follicle development" "Cluster 10: Ciliated cells - Ion channel activity" 18 KRTAP10-11 "KAP10.11, KAP18.11, KRTAP18-11, KRTAP18.11" ENSG00000243489 "Keratin associated protein 10-11" P60412 21 44646414-44647650 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 62 "skin 1: 8.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Skin - Inner root sheath cells" NA NA 110000 "Cluster 9: Skin - Hair follicle development" "Cluster 10: Ciliated cells - Ion channel activity" 33 KRTAP10-12 "KAP10.12, KRTAP18-12, KRTAP18.12" ENSG00000189169 "Keratin associated protein 10-12" P60413 21 44697172-44698044 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 51 "skin 1: 9.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Skin - Inner root sheath cells" NA NA 24000 "Cluster 9: Skin - Hair follicle development" "Cluster 10: Ciliated cells - Ion channel activity" KRTAP10-2 "KAP10.2, KAP18.2, KRTAP18-2" ENSG00000205445 "Keratin associated protein 10-2" P60368 21 44550357-44551505 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 100 "skin 1: 13.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Skin - Inner root sheath cells" NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 51: Myeloma - Immunoglobulins" KRTAP10-3 "KAP10.3, KAP18.3, KRTAP18-3" ENSG00000212935 "Keratin associated protein 10-3" P60369 21 44557790-44558795 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 82 "skin 1: 21.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Skin - Inner root sheath cells" NA NA "Cluster 9: Skin - Hair follicle development" 4 KRTAP10-4 "KAP10.4, KRTAP18-4, KRTAP18.4" ENSG00000215454 "Keratin associated protein 10-4" P60372 21 44573729-44575371 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 58 "skin 1: 6.9" "Cell type enhanced" "Detected in single" "Podocytes: 2.3" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 2.7;medium spiny neuron: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Skin - Inner root sheath cells" NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 98: Neurons - Neurotransmission & signaling" 7 KRTAP10-5 "KAP10.5, KAP18.5, KRTAP18-5" ENSG00000241123 "Keratin associated protein 10-5" P60370 21 44579455-44580604 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 72 "skin 1: 15.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Skin - Inner root sheath cells" NA NA "Cluster 9: Skin - Hair follicle development" 135 KRTAP10-6 "KAP10.6, KAP18.6, KRTAP18-6, KRTAP18.6" ENSG00000188155 "Keratin associated protein 10-6" P60371 21 44591268-44592505 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 11 "skin 1: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Skin - Inner root sheath cells" NA NA "Cluster 9: Skin - Hair follicle development" 65 KRTAP10-7 "KAP10.7, KAP18.7, KRTAP18-7" ENSG00000272804 "Keratin associated protein 10-7" P60409 21 44600597-44602174 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 65 "skin 1: 13.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Skin - Inner root sheath cells" NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 257 KRTAP10-8 "KAP10.8, KRTAP18-8, KRTAP18.8" ENSG00000187766 "Keratin associated protein 10-8" P60410 21 44612079-44612954 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 71 "skin 1: 7.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Skin - Inner root sheath cells" NA NA "Cluster 9: Skin - Hair follicle development" 331 KRTAP10-9 "KAP10.9, KAP18.9, KRTAP18-9" ENSG00000221837 "Keratin associated protein 10-9" P60411 21 44627093-44628378 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 75 "skin 1: 10.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Skin - Inner root sheath cells" NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 190 KRTAP11-1 KAP11.1 ENSG00000182591 "Keratin associated protein 11-1" Q8IUC1 21 30880644-30881580 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 39 "skin 1: 187.3" "Cell type enriched" "Detected in single" 15 "Suprabasal keratinocytes: 5.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Skin - Inner root sheath cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA054008 Enhanced NA NA 130000 "Cluster 9: Skin - Hair follicle development" "Cluster 65: Non-specific - Unknown function" "Cluster 85: Squamous epithelial cells - Keratinization" 84 "HPA054008: " KRTAP12-1 "KAP12.1, KRTAP12.1" ENSG00000187175 "Keratin associated protein 12-1" P59990 21 44681576-44682163 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 59 "skin 1: 22.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "choroid plexus: 1.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Skin - Inner root sheath cells" NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 36: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" 50 KRTAP12-2 "KAP12.2, KRTAP12.2" ENSG00000221864 "Keratin associated protein 12-2" P59991 21 44666189-44666927 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 53 "skin 1: 20.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "choroid plexus: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Skin - Inner root sheath cells" NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 36: Choroid plexus - Mixed function" 98 KRTAP12-3 KRTAP12.3 ENSG00000205439 "Keratin associated protein 12-3" P60328 21 44657932-44658341 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 76 "skin 1: 8.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Skin - Inner root sheath cells" NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 9: T-cells - Adaptive immunity: Regulation" 117 KRTAP12-4 KRTAP12.4 ENSG00000212933 "Keratin associated protein 12-4" P60329 21 44654213-44654659 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Skin - Inner root sheath cells" NA NA 41 KRTAP13-1 KAP13.1 ENSG00000198390 "Keratin associated protein 13-1" Q8IUC0 21 30396031-30396822 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 11 "skin 1: 8.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Skin - Inner root sheath cells, Testis - Late spermatids" "Not detected" "Not detected" NA NA "Cluster 9: Skin - Hair follicle development" KRTAP13-2 KAP13-2 ENSG00000182816 "Keratin associated protein 13-2" Q52LG2 21 30371390-30372271 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "skin 1: 11.3" "Cell type enriched" "Detected in some" 12 "Colonocytes: 16.9" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "Prostate Adenocarcinoma (TCGA): 2.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enterocytes, Skin - Hair cortex cells, Skin - Inner root sheath cells" NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 69: Skin cancer - ECM organization" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 57 "unprognostic (5.42e-2)" KRTAP13-3 KAP13.3 ENSG00000240432 "Keratin associated protein 13-3" Q3SY46 21 30425380-30425926 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells" "Not detected" "Not detected" NA NA 58 KRTAP13-4 KAP13.4 ENSG00000186971 "Keratin associated protein 13-4" Q3LI77 21 30430220-30431026 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 108: Fibroblasts - ECM organization" 6 KRTAP15-1 KAP15.1 ENSG00000186970 "Keratin associated protein 15-1" Q3LI76 21 30440275-30440869 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 53 KRTAP16-1 KAP16.1 ENSG00000212657 "Keratin associated protein 16-1" A8MUX0 17 41307700-41309309 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 16 "skin 1: 15.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Skin - Inner root sheath cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA070954 Enhanced NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 55: Lymphoma - Immune response" "HPA070954: " KRTAP17-1 KAP17.1 ENSG00000186860 "Keratin associated protein 17-1" Q9BYP8 17 41314912-41315710 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 53 "skin 1: 21.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Skin - Inner root sheath cells" "Not detected" "Not detected" NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 55: Lymphoma - Immune response" 41 KRTAP19-1 KAP19.1 ENSG00000184351 "Keratin associated protein 19-1" Q8IUB9 21 30479706-30480367 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "skin 1: 16.7" "Cell type enriched" "Detected in single" 35 "Syncytiotrophoblasts: 3.5" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 8 "Skin Cutaneous Melanoma (TCGA): 29.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 47 "skin cancer: 15.2" "Skin - Hair cortex cells, Skin - Inner root sheath cells" NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 36 "unprognostic (7.32e-2)" "unprognostic (7.30e-3)" "unprognostic (3.67e-2)" "unprognostic (2.08e-2)" KRTAP19-2 KAP19.2 ENSG00000186965 "Keratin associated protein 19-2" Q3LHN2 21 30487043-30487436 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 33 KRTAP19-3 KAP19.3 ENSG00000244025 "Keratin associated protein 19-3" Q7Z4W3 21 30491462-30492013 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "skeletal muscle: 6.9;skin 1: 15.3" "Cell type enriched" "Detected in single" 24 "Medullary thymic epithelial cells: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Skin - Inner root sheath cells" "Not detected" "Not detected" NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 11 KRTAP19-4 KAP19.4 ENSG00000186967 "Keratin associated protein 19-4" Q3LI73 21 30496824-30497165 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Skin - Inner root sheath cells" NA NA "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 82: Dendritic cells - Antigen presentation" 2 KRTAP19-5 KAP19.5 ENSG00000186977 "Keratin associated protein 19-5" Q3LI72 21 30501657-30502141 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 25 "skin 1: 30.8" "Cell type enriched" "Detected in single" 8 "Syncytiotrophoblasts: 3.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Skin - Inner root sheath cells" NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 66: Non-specific - Mitochondria" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 83 KRTAP19-6 KAP19.6 ENSG00000186925 "Keratin associated protein 19-6" Q3LI70 21 30541535-30541864 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells" "Not detected" "Not detected" NA NA 50 KRTAP19-7 KAP19.7 ENSG00000244362 "Keratin associated protein 19-7" Q3SYF9 21 30560875-30561314 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells" NA NA 72 KRTAP19-8 ENSG00000206102 "Keratin associated protein 19-8" Q3LI54 21 31038159-31038476 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Early spermatids: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 65: Non-specific - Unknown function" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" KRTAP2-1 KAP2.1A ENSG00000212725 "Keratin associated protein 2-1" Q9BYU5 17 41046541-41047316 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 60 "skin 1: 61.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells" HPA059203 Supported NA NA "Cluster 9: Skin - Hair follicle development" "HPA059203: " KRTAP2-2 KAP2.2 ENSG00000214518 "Keratin associated protein 2-2" Q9BYT5 17 41054498-41055230 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 59 "skin 1: 49.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells" HPA059203 Supported NA NA "Cluster 9: Skin - Hair follicle development" "HPA059203: " KRTAP2-3 KAP2.3 ENSG00000212724 "Keratin associated protein 2-3" P0C7H8 17 41059240-41060114 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 53 "skin 1: 18.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Uterine Corpus Endometrial Carcinoma (TCGA): 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skin - Hair cortex cells" HPA059203 Supported NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 72: Neuronal - Signal transduction" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 9 "HPA059203: " "unprognostic (1.20e-2)" KRTAP2-4 KAP2.4 ENSG00000213417 "Keratin associated protein 2-4" Q9BYR9 17 41065116-41065879 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 53 "skin 1: 39.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells" HPA059203 Supported NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 72: Neuronal - Signal transduction" 78 "HPA059203: " KRTAP20-1 KAP20.1 ENSG00000244624 "Keratin associated protein 20-1" Q3LI63 21 30616425-30616699 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells" NA NA "Cluster 55: Lymphoma - Immune response" KRTAP20-2 KAP20.2 ENSG00000184032 "Keratin associated protein 20-2" Q3LI61 21 30635206-30635619 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "skin 1: 1.6" "Cell type enhanced" "Detected in single" "Gonadotrophs: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells" "Not detected" "Not detected" NA NA "Cluster 37: Skin - Keratinization" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" KRTAP20-3 "KAP19D, KAP20.3, KRTAP19P4" ENSG00000206104 "Keratin associated protein 20-3" Q3LI60 21 30642864-30643136 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA053598 Uncertain NA NA "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 108: Fibroblasts - ECM organization" "HPA053598: " KRTAP20-4 KAP20.4 ENSG00000206105 "Keratin associated protein 20-4" Q3LI62 21 30620627-30620850 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 19 "testis: 1.9" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 2.0;Gonadotrophs: 2.9;Late primary spermatocytes: 1.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Prostate Adenocarcinoma (TCGA): 1.4;Testicular Germ Cell Tumor (TCGA): 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 1.1;Myeloma: 1.1;thyroid cancer: 1.2" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" "unprognostic (3.83e-1)" "unprognostic (8.41e-1)" KRTAP21-1 KAP21.1 ENSG00000187005 "Keratin associated protein 21-1" Q3LI58 21 30755015-30755428 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA KRTAP21-2 KAP21.2 ENSG00000187026 "Keratin associated protein 21-2" Q3LI59 21 30746794-30747259 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "skin 1: 1.3;testis: 1.5" "Group enriched" "Detected in some" 9 "Early spermatids: 4.5;Late primary spermatocytes: 8.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Skin - Inner root sheath cells, Testis - Early spermatids, Testis - Late spermatids" NA NA "Cluster 47: Testis - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" 25 KRTAP21-3 ENSG00000231068 "Keratin associated protein 21-3" Q3LHN1 21 30718525-30718777 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA046554 Uncertain NA NA "Cluster 15: Kidney cancer - Membrane components" "HPA046554: " KRTAP22-1 KAP22.1 ENSG00000186924 "Keratin associated protein 22-1" Q3MIV0 21 30601087-30601382 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 10: Ciliated cells - Ion channel activity" KRTAP22-2 KAP22.2 ENSG00000206106 "Keratin associated protein 22-2" Q3LI68 21 30590105-30590397 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 16: Thyroid cancer - Neuronal signaling" KRTAP23-1 KAP23.1 ENSG00000186980 "Keratin associated protein 23-1" A1A580 21 30348399-30348606 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Skin - Inner root sheath cells" NA NA 4 KRTAP24-1 KAP24.1 ENSG00000188694 "Keratin associated protein 24-1" Q3LI83 21 30281309-30282950 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 33 "skin 1: 5.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Skin - Inner root sheath cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA017604 Enhanced NA NA "Cluster 9: Skin - Hair follicle development" "HPA017604: " KRTAP25-1 KAP25.1 ENSG00000232263 "Keratin associated protein 25-1" Q3LHN0 21 30289145-30289514 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA031438 Uncertain Approved "Nuclear membrane,Plasma membrane,Cytosol" NA NA "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" "Nuclear membrane" "Plasma membrane, Cytosol" "HPA031438: " KRTAP26-1 ENSG00000197683 "Keratin associated protein 26-1" Q6PEX3 21 30319124-30320315 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "skin 1: 17.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Skin - Inner root sheath cells" "Not detected" "Not detected" NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 74 KRTAP27-1 ENSG00000206107 "Keratin associated protein 27-1" Q3LI81 21 30337013-30337694 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA021522, HPA048826" Approved NA NA "HPA021522: , HPA048826: " KRTAP29-1 KAP29.2 ENSG00000212658 "Keratin associated like protein 29-1" A8MX34 17 41301826-41302851 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 17 "skin 1: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Skin - Inner root sheath cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 55: Lymphoma - Immune response" KRTAP3-1 KAP3.1 ENSG00000212901 "Keratin associated protein 3-1" Q9BYR8 17 41008521-41019324 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 72 "skin 1: 218.4" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bladder Urothelial Carcinoma (TCGA): 4.0;Lung Squamous Cell Carcinoma (TCGA): 1.4;Stomach Adenocarcinoma (TCGA): 5.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "cervical cancer: 27.3;colorectal cancer: 8.4" "Skin - Hair cortex cells" "Not detected" "Not detected" NA NA 260000 "Cluster 9: Skin - Hair follicle development" "Cluster 53: Squamous epithelial cells - Keratinization" 61 "unprognostic (6.40e-1)" KRTAP3-2 KAP3.2 ENSG00000212900 "Keratin associated protein 3-2" Q9BYR7 17 40999193-40999906 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "skin 1: 95.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "cervical cancer: 1.5;colorectal cancer: 1.8" "Skin - Hair cortex cells" HPA042992 Approved NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 32: Non-specific - Cell proliferation" 56 "HPA042992: " KRTAP3-3 KAP3.3 ENSG00000212899 "Keratin associated protein 3-3" Q9BYR6 17 40993430-40994164 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 112 "skin 1: 120.5" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Breast Invasive Carcinoma (TCGA): 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "cervical cancer: 3.5" "Skin - Hair cortex cells" HPA042992 Supported NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 53: Squamous epithelial cells - Keratinization" 60 "HPA042992: " KRTAP4-1 "KAP4.1, KAP4.10, KRTAP4-10" ENSG00000198443 "Keratin associated protein 4-1" Q9BYQ7 17 41184100-41184911 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 47 "skin 1: 19.0" "Cell type enhanced" "Detected in some" "Goblet cells: 1.1;Neuroendocrine cells: 2.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Esophageal cancer: 1.5;Gallbladder cancer: 2.0" "Skin - Hair cortex cells" NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 7: Liver cancer - Metabolism" "Cluster 70: Intestinal goblet cells - Mucin production" 22 "unprognostic (1.86e-1)" "unprognostic (3.02e-1)" "unprognostic (4.72e-3)" "unprognostic (4.00e-2)" "unprognostic (1.08e-1)" "unprognostic (1.38e-2)" "unprognostic (2.57e-2)" "unprognostic (4.91e-3)" KRTAP4-11 "KAP4.11, KAP4.14, KRTAP4-14" ENSG00000212721 "Keratin associated protein 4-11" Q9BYQ6 17 41117181-41118373 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 89 "skin 1: 8.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 15 "Bone cancer: 1.4" "Skin - Hair cortex cells" NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 12: Bone cancer - Neuronal signaling" 62 KRTAP4-12 KAP4.12 ENSG00000213416 "Keratin associated protein 4-12" Q9BQ66 17 41123091-41124182 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 81 "skin 1: 24.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.0" "Lineage enhanced" "Detected in single" "B-cells: 1.0" "Not detected" "Not detected" "Skin - Hair cortex cells" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 9: Skin - Hair follicle development" "Cluster 64: Connective tissue cells - ECM organization" 83 KRTAP4-16 "KAP4A, KRTAP4-16P, KRTAP4P1" ENSG00000241241 "Keratin associated protein 4-16" G5E9R7 17 41101502-41102209 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells" NA NA "Cluster 42: Choroid plexus - Mitochondria" "Cluster 72: Neuronal - Signal transduction" KRTAP4-2 KAP4.2 ENSG00000244537 "Keratin associated protein 4-2" Q9BYR5 17 41177446-41178221 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 71 "skin 1: 20.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells" NA NA "Cluster 9: Skin - Hair follicle development" 110 KRTAP4-3 KAP4.3 ENSG00000196156 "Keratin associated protein 4-3" Q9BYR4 17 41167231-41168221 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 136 "skin 1: 16.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 300000 "Cluster 9: Skin - Hair follicle development" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" KRTAP4-4 "KAP4.13, KAP4.4, KRTAP4-13" ENSG00000171396 "Keratin associated protein 4-4" Q9BYR3 17 41159649-41160748 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 66 "skin 1: 17.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells" NA NA 100000 "Cluster 9: Skin - Hair follicle development" "Cluster 5: Rhabdoid - Unknown function" "Cluster 100: Stratified epithelial cells - Barrier functions" 57 KRTAP4-5 KAP4.5 ENSG00000198271 "Keratin associated protein 4-5" Q9BYR2 17 41148924-41149825 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 114 "skin 1: 11.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells" NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 100: Stratified epithelial cells - Barrier functions" 54 KRTAP4-6 "KAP4.15, KAP4.6, KRTAP4-15" ENSG00000198090 "Keratin associated protein 4-6" Q9BYQ5 17 41139433-41140544 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 75 "skin 1: 31.1" "Cell type enriched" "Detected in some" 4 "Endometrial secretory cells: 9.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells" NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" KRTAP4-7 KAP4.7 ENSG00000240871 "Keratin associated protein 4-7" Q9BYR0 17 41084150-41085144 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 79 "skin 1: 53.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells" NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 72: Neuronal - Signal transduction" 11 KRTAP4-8 KAP4.8 ENSG00000204880 "Keratin associated protein 4-8" Q9BYQ9 17 41096981-41098142 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 90 "skin 1: 22.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells" NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 72: Neuronal - Signal transduction" "Cluster 51: Secretory epithelial cells - Mixed function" KRTAP4-9 KAP4.9 ENSG00000212722 "Keratin associated protein 4-9" Q9BYQ8 17 41105389-41106488 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 98 "skin 1: 44.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells" NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 72: Neuronal - Signal transduction" KRTAP5-1 "KRN1L, KRTAP5.1" ENSG00000205869 "Keratin associated protein 5-1" Q6L8H4 11 1584342-1585283 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 11.1;pituitary gland: 4.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 1.3" "Minor Salivary Gland - Minor salivary glandular cells, Skin - Hair cortex cells, Skin - Inner root sheath cells" NA NA "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" 9 "unprognostic (1.86e-1)" "unprognostic (5.36e-2)" KRTAP5-10 KRTAP5.10 ENSG00000204572 "Keratin associated protein 5-10" Q6L8G5 11 71565563-71566735 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "skin 1: 4.5" "Cell type enhanced" "Detected in some" "Early spermatids: 1.4;Ependymal cells: 1.5;Epididymal efferent duct ciliated cells: 2.5;Epididymal principal cells: 6.2;Late primary spermatocytes: 3.5;Late spermatids: 1.5;Papillary tip epithelial cells: 2.0;Sertoli cells: 1.1;Urothelial cells: 4.1" "Cell type enhanced" "Detected in some" "ependymal cell: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Skin - Inner root sheath cells" NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 27: Breast cancer - Unknown function" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" KRTAP5-11 "KRTAP5-6, KRTAP5.11" ENSG00000204571 "Keratin associated protein 5-11" Q6L8G4 11 71581855-71603353 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 5 "skin 1: 4.8" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 1.9;Brain inhibitory neurons: 3.9;Medullary thymic epithelial cells: 2.4;Müller glia: 1.6;Other brain neurons: 1.4;Papillary tip epithelial cells: 2.6;Pituitary stem cells: 1.8;Respiratory ionocytes: 2.5;Retinal ganglion cells: 3.9;Retinal horizontal cells: 2.0" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 9.0;deep-layer near-projecting: 9.9;lower rhombic lip: 13.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Skin - Inner root sheath cells" NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 4: Non-specific - Transcription" "Cluster 109: Neurons - Neuronal signaling" 49 KRTAP5-2 "KRTAP5-8, KRTAP5.2" ENSG00000205867 "Keratin associated protein 5-2" Q701N4 11 1597177-1598294 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 2.1;pancreas: 1.8;skin 1: 4.4" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney Chromophobe (TCGA): 2.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "breast cancer: 1.4" "Skin - Hair cortex cells, Skin - Inner root sheath cells" NA NA "Cluster 2: Non-specific - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" 38 "unprognostic (5.80e-2)" "unprognostic (2.60e-1)" "unprognostic (9.79e-2)" "unprognostic (9.32e-3)" KRTAP5-3 "KRTAP5-9, KRTAP5.3" ENSG00000196224 "Keratin associated protein 5-3" Q6L8H2 11 1607565-1608463 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 75 "skin 1: 7.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Skin - Inner root sheath cells" NA NA "Cluster 9: Skin - Hair follicle development" 39 KRTAP5-4 KRTAP5.4 ENSG00000241598 "Keratin associated protein 5-4" 11 1620958-1622138 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 14 "skin 1: 4.2" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "Uterine Corpus Endometrial Carcinoma (TCGA): 2.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Skin - Inner root sheath cells" "Not detected" "Not detected" NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 10: Ciliated cells - Ion channel activity" "unprognostic (2.09e-1)" KRTAP5-5 "KRTAP5-11, KRTAP5.5" ENSG00000185940 "Keratin associated protein 5-5" Q701N2 11 1629775-1630930 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 6 "skin 1: 3.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Skin - Inner root sheath cells" NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 10: Ciliated cells - Ion channel activity" KRTAP5-6 KRTAP5.6 ENSG00000205864 "Keratin associated protein 5-6" Q6L8G9 11 1697195-1697755 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "liver: 2.9;skin 1: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Skin - Inner root sheath cells" NA NA "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 32: Non-specific - Cell proliferation" 81 KRTAP5-7 "KRTAP5-3, KRTAP5.7" ENSG00000244411 "Keratin associated protein 5-7" Q6L8G8 11 71527267-71528669 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skin 1: 4.8;testis: 1.8" "Cell type enhanced" "Detected in some" "Early spermatids: 1.1;Kupffer cells: 1.0;Late primary spermatocytes: 1.6;Late spermatids: 7.4;Retinal amacrine cells: 2.1" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in single" "Kidney Chromophobe (TCGA): 1.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Skin - Inner root sheath cells, Testis - Early spermatids, Testis - Late spermatids" NA NA "Cluster 2: Non-specific - Mixed function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 50 "unprognostic (1.47e-1)" KRTAP5-8 "KRTAP5-2, KRTAP5.8, UHSKerB" ENSG00000241233 "Keratin associated protein 5-8" O75690 11 71538025-71539209 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "kidney: 5.7;skin 1: 6.9" "Cell type enriched" "Detected in some" 4 "Epididymal clear cells: 12.2" "Cell type enhanced" "Detected in single" "thalamic excitatory: 1.2" "Cancer enriched" "Detected in some" 26 "Kidney Chromophobe (TCGA): 29.3" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Skin - Inner root sheath cells" NA NA "Cluster 58: Skin - Keratinization" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 3 "unprognostic (1.42e-1)" "unprognostic (1.08e-1)" KRTAP5-9 "KRN1, KRTAP5-1, KRTAP5.9" ENSG00000254997 "Keratin associated protein 5-9" P26371 11 71548420-71549608 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 3.0" "Cell type enhanced" "Detected in some" "Early spermatids: 1.4;Epididymal clear cells: 2.0;Late primary spermatocytes: 3.2;Late spermatids: 10.1;Respiratory deuterosomal cells: 1.0;Urothelial cells: 1.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder Urothelial Carcinoma (TCGA): 2.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" NA NA "Cluster 67: Testis - Mixed function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 170 "unprognostic (2.01e-1)" "unprognostic (1.22e-1)" KRTAP6-1 "C21orf103, KAP6.1" ENSG00000184724 "Keratin associated protein 6-1" Q3LI64 21 30613431-30613930 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 9 "skin 1: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells" NA NA "Cluster 9: Skin - Hair follicle development" 71 KRTAP6-2 KAP6.2 ENSG00000186930 "Keratin associated protein 6-2" Q3LI66 21 30598590-30598902 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 137 KRTAP6-3 KAP6.3 ENSG00000212938 "Keratin associated protein 6-3" Q3LI67 21 30592440-30593075 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 128 KRTAP7-1 KAP7.1 ENSG00000274749 "Keratin associated protein 7-1" Q8IUC3 21 30829039-30829759 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 28 "skin 1: 22.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 55: Lymphoma - Immune response" 28 KRTAP8-1 KAP8.1 ENSG00000183640 "Keratin associated protein 8-1" Q8IUC2 21 30812697-30813274 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 25 "skin 1: 60.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 76 KRTAP9-1 "KAP9.1, KRTAP9L3" ENSG00000240542 "Keratin associated protein 9-1" A8MXZ3 17 41189887-41190639 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells" NA NA "Cluster 5: Rhabdoid - Unknown function" "Cluster 108: Fibroblasts - ECM organization" KRTAP9-2 KAP9.2 ENSG00000239886 "Keratin associated protein 9-2" Q9BYQ4 17 41226648-41227652 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 74 "skin 1: 27.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells" NA NA "Cluster 9: Skin - Hair follicle development" 126 KRTAP9-3 KAP9.3 ENSG00000204873 "Keratin associated protein 9-3" Q9BYQ3 17 41232449-41233454 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 91 "skin 1: 45.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells" NA NA "Cluster 9: Skin - Hair follicle development" 103 KRTAP9-4 KAP9.4 ENSG00000241595 "Keratin associated protein 9-4" Q9BYQ2 17 41249687-41250653 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 86 "skin 1: 37.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells" NA NA "Cluster 9: Skin - Hair follicle development" 25 KRTAP9-6 "KAP9.6, KRTAP9L2" ENSG00000212659 "Keratin associated protein 9-6" A8MVA2 17 41265378-41265860 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 25 "skin 1: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells" NA NA "Cluster 9: Skin - Hair follicle development" KRTAP9-7 "KAP9.7, KRTAP9L1" ENSG00000180386 "Keratin associated protein 9-7" A8MTY7 17 41275698-41276207 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 78 "skin 1: 7.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells" NA NA "Cluster 9: Skin - Hair follicle development" KRTAP9-8 KAP9.8 ENSG00000187272 "Keratin associated protein 9-8" Q9BYQ0 17 41237999-41239004 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 72 "skin 1: 41.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells" NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 21: Lymphoma - Adaptive immune response" 72 KRTAP9-9 "KAP9.5, KAP9.9, KRTAP9-5" ENSG00000198083 "Keratin associated protein 9-9" Q9BYP9 17 41255384-41256364 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 90 "skin 1: 22.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells" NA NA "Cluster 9: Skin - Hair follicle development" KRTCAP2 KCP2 ENSG00000163463 "Keratinocyte associated protein 2" Q8N6L1 1 155169408-155173475 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 119.6;Gastric chief cells: 286.1;Late primary spermatocytes: 125.4;Parietal cells: 198.0;Plasma cells: 131.1" "Cell type enhanced" "Detected in many" "pericyte: 13.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 70: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 45: Non-specific - Nuclear processes" "Cluster 67: Plasma cells - Plasma cell differentiation" 33 "unprognostic (4.02e-3)" "unprognostic (2.81e-1)" "unprognostic (4.40e-1)" "unprognostic (1.20e-1)" "unprognostic (2.02e-1)" "unprognostic (2.23e-2)" "unprognostic (1.12e-1)" "unprognostic (1.77e-3)" "potential prognostic unfavorable (3.61e-4)" "unprognostic (3.80e-1)" "potential prognostic unfavorable (2.83e-7)" "unprognostic (2.74e-2)" "unprognostic (5.97e-3)" "potential prognostic unfavorable (2.16e-4)" "unprognostic (4.80e-2)" "unprognostic (1.65e-1)" "unprognostic (1.20e-1)" "unprognostic (2.07e-1)" "unprognostic (2.09e-1)" "unprognostic (1.08e-1)" "unprognostic (1.18e-1)" "unprognostic (4.85e-2)" "unprognostic (1.01e-1)" "unprognostic (4.13e-2)" "potential prognostic unfavorable (4.36e-4)" "unprognostic (1.47e-2)" "unprognostic (1.51e-1)" "unprognostic (2.02e-1)" "unprognostic (1.68e-1)" "unprognostic (1.40e-1)" "unprognostic (4.18e-2)" KRTCAP3 KCP3 ENSG00000157992 "Keratinocyte associated protein 3" Q53RY4 2 27442366-27446481 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast lactating cells: 217.3;Breast secretory cells: 133.2;Enteric stem cells: 190.7;Enteric transient amplifying cells: 197.4;Enterocytes: 158.3;Fallopian tube ciliated cells: 133.3;Gastric progenitor cells: 235.8;Paneth cells: 174.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "MAIT T-cell: 6.8;memory B-cell: 4.5;memory CD4 T-cell: 5.7;memory CD8 T-cell: 2.6;naive B-cell: 6.5;naive CD4 T-cell: 6.6;naive CD8 T-cell: 2.7;T-reg: 4.4" "Group enriched" "Detected in many" 13 "B-cells: 6.5;T-cells: 6.8" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Lung - Alveolar cells type 2, Prostate - Prostate basal glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA047136, HPA060203" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 60: Stomach - Digestion" "Cluster 6: Non-specific - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 1 "Nucleoplasm, Cytosol" "HPA047136: , HPA060203: " "unprognostic (2.03e-1)" "potential prognostic favorable (1.67e-4)" "unprognostic (3.04e-1)" "unprognostic (5.51e-2)" "unprognostic (7.80e-2)" "unprognostic (8.35e-2)" "unprognostic (1.13e-1)" "unprognostic (1.28e-3)" "unprognostic (9.44e-2)" "unprognostic (1.21e-1)" "unprognostic (3.89e-2)" "unprognostic (7.77e-2)" "unprognostic (7.60e-2)" "unprognostic (1.07e-1)" "unprognostic (2.38e-1)" "unprognostic (2.67e-2)" "unprognostic (2.13e-1)" "unprognostic (1.62e-1)" "unprognostic (2.50e-1)" "unprognostic (1.51e-2)" "unprognostic (1.90e-2)" "unprognostic (3.47e-3)" "unprognostic (2.27e-1)" "unprognostic (1.61e-1)" "unprognostic (1.51e-1)" "unprognostic (1.05e-1)" "unprognostic (3.29e-1)" "unprognostic (1.21e-2)" "unprognostic (1.84e-1)" "unprognostic (1.76e-1)" "unprognostic (2.22e-1)" KRTDAP "KDAP, UNQ467" ENSG00000188508 "Keratinocyte differentiation associated protein" P60985 19 35487324-35495558 "Plasma proteins, Predicted secreted proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 1599.0;skin 1: 7413.9;vagina: 2040.8" "Cell type enriched" "Detected in many" 7 "Suprabasal keratinocytes: 5941.3" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 1.7" "Group enriched" "Detected in many" 4 "Head and Neck Squamous Cell Carcinoma (TCGA): 1648.3;Skin Cutaneous Melanoma (TCGA): 575.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "Esophageal cancer: 42.8;head and neck cancer: 38.2" "Region enriched" "Detected in single" 6 "white matter: 1.6" "Not detected" "Not detected" HPA063474 Enhanced "Secreted in other tissues" Other NA NA 13000000 "Cluster 37: Skin - Keratinization" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" "HPA063474: " "unprognostic (3.74e-1)" "unprognostic (1.42e-1)" "unprognostic (1.82e-1)" "unprognostic (2.44e-1)" "unprognostic (6.68e-2)" "unprognostic (1.14e-1)" "unprognostic (3.06e-2)" "unprognostic (2.76e-1)" "unprognostic (1.85e-2)" "unprognostic (2.82e-1)" "unprognostic (4.95e-3)" "unprognostic (1.40e-1)" "unprognostic (5.24e-2)" "unprognostic (1.07e-1)" "unprognostic (4.59e-1)" KSR1 "KSR, RSU2" ENSG00000141068 "Kinase suppressor of ras 1" Q8IVT5 17 27456448-27626438 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 104.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 271.2;Pancreatic acinar cells: 198.2;Respiratory secretory cells: 227.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 57.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 3.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009623, HPA011215, HPA011878" Uncertain Supported Vesicles,Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 29: Forebrain - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 51: Secretory epithelial cells - Mixed function" 29 Cytosol Vesicles "CAB009623: , HPA011215: , HPA011878: " "unprognostic (5.84e-2)" "unprognostic (1.04e-1)" "unprognostic (8.14e-3)" "unprognostic (1.04e-1)" "unprognostic (1.92e-1)" "unprognostic (1.23e-1)" "unprognostic (1.77e-1)" "unprognostic (1.08e-2)" "unprognostic (5.70e-2)" "unprognostic (3.45e-3)" "potential prognostic favorable (4.10e-6)" "unprognostic (5.32e-3)" "unprognostic (2.41e-2)" "potential prognostic unfavorable (2.78e-4)" "unprognostic (2.18e-1)" "unprognostic (1.03e-2)" "unprognostic (2.87e-1)" "unprognostic (1.93e-1)" "unprognostic (8.18e-2)" "unprognostic (7.08e-3)" "unprognostic (4.01e-2)" "unprognostic (1.48e-1)" "unprognostic (2.07e-2)" "unprognostic (2.60e-1)" "unprognostic (2.71e-2)" "unprognostic (1.79e-2)" "unprognostic (2.43e-1)" "unprognostic (1.72e-2)" "unprognostic (1.83e-1)" "unprognostic (2.87e-2)" "unprognostic (3.28e-2)" KSR2 FLJ25965 ENSG00000171435 "Kinase suppressor of ras 2" Q6VAB6 12 117453012-117968990 "Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.4;pituitary gland: 7.4" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 425.9;Brain inhibitory neurons: 338.2;Corticotrophs: 531.7;Gonadotrophs: 642.3;Lactotrophs: 1078.3;Other brain neurons: 278.5;Renal collecting duct principal cells: 737.2;Retinal amacrine cells: 263.7;Somatotrophs: 887.3;Thyrotrophs: 906.3" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Adrenal gland - Adrenal medulla cells, Breast - Breast glandular cells, Colon - Colon enteroendocrine cells, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary gland ductal cells, Pituitary gland - Lactotropes, Stomach - Gastric enteroendocrine cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035536 Enhanced NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 51: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 18 "HPA035536: " "unprognostic (1.30e-1)" "unprognostic (9.35e-2)" "unprognostic (3.41e-3)" "unprognostic (1.24e-3)" KTI12 "MGC20419, SBBI81, TOT4" ENSG00000198841 "KTI12 chromatin associated homolog" Q96EK9 1 52032103-52033810 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in single" 6 "Thymic myoid cells: 1.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031203, HPA031204, HPA031205" Approved Approved "Nuclear speckles,Cytoplasmic bodies" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 15: Bone marrow - Innate immune response" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 37: Non-specific - mRNA processing" "Cluster 79: Photoreceptor cells - Phototransduction" 3 "Nuclear speckles, Cytoplasmic bodies" "HPA031203: , HPA031204: , HPA031205: " "unprognostic (4.75e-2)" "unprognostic (1.73e-1)" "unprognostic (7.30e-2)" "unprognostic (1.34e-1)" "unprognostic (1.96e-3)" "unprognostic (1.83e-1)" "unprognostic (3.25e-2)" "unprognostic (5.02e-3)" "unprognostic (5.69e-2)" "unprognostic (1.12e-1)" "potential prognostic favorable (3.68e-4)" "unprognostic (3.31e-2)" "unprognostic (1.30e-3)" "validated prognostic unfavorable (1.97e-5)" "validated prognostic unfavorable (2.18e-5)" "unprognostic (1.15e-1)" "unprognostic (1.49e-2)" "unprognostic (3.17e-1)" "unprognostic (3.31e-2)" "unprognostic (1.75e-1)" "unprognostic (2.20e-3)" "unprognostic (5.89e-2)" "unprognostic (1.33e-2)" "unprognostic (3.97e-3)" "unprognostic (1.44e-1)" "unprognostic (1.39e-1)" "unprognostic (2.89e-1)" "unprognostic (1.04e-1)" "unprognostic (2.21e-1)" "unprognostic (4.92e-1)" "unprognostic (1.18e-1)" KTN1 "CG1, KIAA0004, KNT" ENSG00000126777 "Kinectin 1" Q86UP2 14 55559072-55701526 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Spleen - Endothelial cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003178, CAB015331, HPA017876" Enhanced Enhanced "Endoplasmic reticulum" NA NA 36000 "Cluster 30: Non-specific - DNA binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 26: Keratinocytes - Keratinization" 32 "Endoplasmic reticulum" "CAB015331: , HPA003178: , HPA017876: " "unprognostic (1.59e-2)" "unprognostic (1.96e-2)" "potential prognostic unfavorable (7.21e-4)" "unprognostic (1.55e-1)" "unprognostic (1.63e-2)" "unprognostic (1.51e-1)" "unprognostic (9.58e-2)" "unprognostic (2.08e-1)" "potential prognostic unfavorable (6.31e-4)" "unprognostic (1.56e-3)" "potential prognostic favorable (1.20e-5)" "unprognostic (5.35e-3)" "unprognostic (1.56e-1)" "potential prognostic unfavorable (5.55e-5)" "unprognostic (1.61e-2)" "unprognostic (3.03e-3)" "unprognostic (1.57e-1)" "unprognostic (5.30e-2)" "unprognostic (4.33e-2)" "unprognostic (2.72e-2)" "unprognostic (2.01e-2)" "unprognostic (2.39e-1)" "unprognostic (5.28e-3)" "unprognostic (2.08e-1)" "unprognostic (8.34e-2)" "unprognostic (4.67e-2)" "unprognostic (2.01e-2)" "unprognostic (4.73e-2)" "unprognostic (3.06e-1)" "unprognostic (3.60e-1)" "unprognostic (2.40e-1)" KXD1 "BORCS4, C19orf50, FLJ25480, KXDL, MGC2749" ENSG00000105700 "KxDL motif containing 1" Q9BQD3 19 18557762-18569387 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 236.1;Hofbauer cells: 146.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "HPA041507, HPA041599" Approved Approved "Nucleoli fibrillar center,Centrosome,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 90 "Nucleoli fibrillar center, Centrosome, Cytosol" "HPA041507: , HPA041599: " "unprognostic (1.41e-1)" "unprognostic (4.07e-2)" "unprognostic (8.11e-3)" "unprognostic (5.06e-2)" "unprognostic (4.78e-1)" "unprognostic (2.82e-1)" "unprognostic (3.07e-2)" "unprognostic (2.30e-2)" "unprognostic (3.20e-3)" "unprognostic (1.02e-2)" "unprognostic (1.17e-3)" "unprognostic (2.18e-1)" "potential prognostic unfavorable (1.27e-5)" "unprognostic (1.86e-1)" "unprognostic (9.20e-2)" "unprognostic (2.63e-1)" "unprognostic (2.19e-3)" "unprognostic (1.75e-1)" "unprognostic (1.03e-1)" "unprognostic (1.37e-1)" "unprognostic (1.09e-1)" "unprognostic (1.03e-2)" "unprognostic (6.95e-2)" "unprognostic (1.12e-2)" "unprognostic (2.38e-2)" "unprognostic (5.39e-2)" "unprognostic (5.73e-2)" "unprognostic (1.67e-1)" "unprognostic (4.14e-2)" KY FLJ33207 ENSG00000174611 "Kyphoscoliosis peptidase" Q8NBH2 3 134599923-134651636 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease" "Myofibrillar myopathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 15.2;tongue: 25.9" "Cell type enhanced" "Detected in many" "Astrocytes: 29.0;Cardiomyocytes: 116.6;Corticotrophs: 67.5;Ependymal cells: 35.1;Gonadotrophs: 34.8;Lactotrophs: 83.9;Müller glia: 31.1;Myonuclei: 31.0;Oligodendrocyte progenitor cells: 48.0;Retinal amacrine cells: 34.0;Retinal ganglion cells: 38.6;Retinal pigment epithelial cells: 38.4;Somatotrophs: 29.0;Thyrotrophs: 51.5" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 104.2" "Cancer enhanced" "Detected in single" "Thyroid Carcinoma (TCGA): 1.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 5.7;neutrophil: 2.2" "Lineage enriched" "Detected in single" 58 "granulocytes: 5.7" "Not detected" "Not detected" "Adipose subcutaneous - Smooth muscle cells, Breast - Breast myoepithelial cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 12.4" "HPA036492, HPA036668" Uncertain Approved Nucleoplasm NA NA "Cluster 41: Basophils - Unknown function" "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" Nucleoplasm "HPA036492: , HPA036668: " "unprognostic (2.59e-1)" "unprognostic (1.98e-1)" "unprognostic (1.80e-1)" KYAT1 "CCBL1, GTK, KATI" ENSG00000171097 "Kynurenine aminotransferase 1" Q16773 9 128832942-128882494 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Aminotransferase, Lyase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 37.9;Bergmann glia: 54.8;Brain excitatory neurons: 43.2;Brain inhibitory neurons: 47.6;Choroid plexus epithelial cells: 77.7;Distal convoluted tubule cells: 28.6;Ependymal cells: 25.4;Loop of henle epithelial cells: 30.7;Oligodendrocyte progenitor cells: 19.8;Oligodendrocytes: 22.4;Other brain neurons: 33.8;Papillary tip epithelial cells: 24.6;Podocytes: 79.5;Proximal tubule cells: 29.6;Renal collecting duct principal cells: 29.5;Renal connecting tubule cells: 29.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021176, HPA021177, HPA027736" Approved Supported Cytosol NA NA 11000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 102: Non-specific - Mixed function" 4 Cytosol "HPA021176: , HPA021177: , HPA027736: " "unprognostic (1.24e-1)" "unprognostic (2.95e-2)" "unprognostic (1.93e-1)" "unprognostic (4.73e-3)" "unprognostic (1.96e-1)" "unprognostic (1.45e-2)" "potential prognostic favorable (9.25e-6)" "unprognostic (2.27e-1)" "unprognostic (2.56e-1)" "potential prognostic favorable (1.22e-4)" "unprognostic (1.14e-3)" "potential prognostic favorable (5.64e-5)" "unprognostic (4.80e-2)" "unprognostic (3.22e-2)" "unprognostic (5.32e-2)" "unprognostic (4.03e-2)" "unprognostic (7.57e-3)" "unprognostic (7.08e-2)" "unprognostic (4.99e-2)" "unprognostic (1.19e-1)" "unprognostic (1.25e-2)" "unprognostic (1.84e-1)" "unprognostic (2.22e-1)" "unprognostic (1.90e-1)" "unprognostic (3.34e-1)" "unprognostic (5.88e-2)" "unprognostic (6.73e-2)" "unprognostic (2.98e-2)" "unprognostic (2.64e-2)" KYAT3 "CCBL2, KAT3, KATIII, RBM1, RP11-82K18.3" ENSG00000137944 "Kynurenine aminotransferase 3" Q6YP21 1 88935773-88992953 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Aminotransferase, Lyase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026538, HPA027168" Enhanced Approved "Nucleoli,Cytokinetic bridge,Cytosol" Yes NA "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 23: Choroid plexus - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 2 Cytosol "Nucleoli, Cytokinetic bridge" "HPA026538: , HPA027168: " "unprognostic (1.16e-2)" "potential prognostic favorable (4.76e-5)" "unprognostic (1.24e-1)" "potential prognostic favorable (4.52e-4)" "unprognostic (1.40e-2)" "unprognostic (3.28e-2)" "unprognostic (1.42e-1)" "unprognostic (3.29e-3)" "unprognostic (6.40e-2)" "potential prognostic favorable (6.60e-8)" "unprognostic (1.72e-3)" "potential prognostic favorable (1.32e-5)" "unprognostic (9.45e-2)" "unprognostic (3.39e-2)" "unprognostic (1.75e-2)" "unprognostic (8.31e-2)" "unprognostic (2.35e-1)" "unprognostic (2.73e-2)" "unprognostic (4.41e-1)" "unprognostic (1.49e-1)" "unprognostic (1.32e-1)" "unprognostic (1.55e-1)" "unprognostic (1.29e-1)" "unprognostic (1.32e-1)" "unprognostic (2.73e-1)" "unprognostic (1.30e-1)" "unprognostic (4.35e-2)" "unprognostic (8.24e-2)" "unprognostic (5.63e-2)" KYNU ENSG00000115919 Kynureninase Q16719 2 142877657-143055833 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 82.6;urinary bladder: 48.0" "Cell type enhanced" "Detected in many" "B-cells: 234.9;cDC: 837.5;Endometrial secretory cells: 330.9;Kupffer cells: 259.3;Macrophages: 585.3;Megakaryocyte-Erythroid progenitors: 251.1;monocytes: 1977.3;Syncytiotrophoblasts: 408.3;Urothelial cells: 346.0" "Group enriched" "Detected in some" 15 "central nervous system macrophage: 180.0;endothelial cell: 66.6;leukocyte: 143.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 17 "classical monocyte: 109.6;intermediate monocyte: 142.9;memory B-cell: 73.8;myeloid DC: 111.3;naive B-cell: 51.6;non-classical monocyte: 124.0;plasmacytoid DC: 77.8" "Group enriched" "Detected in many" 19 "B-cells: 73.8;dendritic cells: 111.3;monocytes: 142.9" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Heart muscle - Macrophages, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA031686 Enhanced Supported Nucleoplasm,Cytosol NA NA 550000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 48: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 2 Cytosol Nucleoplasm "HPA031686: " "unprognostic (1.59e-1)" "unprognostic (2.26e-2)" "unprognostic (1.25e-1)" "potential prognostic unfavorable (8.56e-4)" "unprognostic (3.59e-1)" "unprognostic (7.51e-2)" "unprognostic (4.08e-2)" "unprognostic (3.24e-1)" "unprognostic (7.38e-2)" "unprognostic (1.60e-2)" "unprognostic (1.82e-2)" "unprognostic (1.97e-1)" "potential prognostic unfavorable (4.65e-4)" "unprognostic (2.63e-2)" "unprognostic (3.29e-1)" "potential prognostic unfavorable (1.51e-4)" "unprognostic (1.35e-1)" "unprognostic (8.47e-2)" "unprognostic (1.48e-1)" "unprognostic (1.91e-1)" "unprognostic (8.76e-2)" "unprognostic (1.10e-3)" "potential prognostic unfavorable (6.85e-5)" "unprognostic (5.28e-2)" "unprognostic (8.72e-2)" "unprognostic (1.89e-2)" "unprognostic (3.05e-2)" "unprognostic (1.01e-2)" "unprognostic (5.05e-2)" "unprognostic (2.97e-2)" "unprognostic (2.97e-1)" L1CAM "CAML1, CD171, HSAS, HSAS1, MASA, MIC5, NCAM-L1, S10, SPG1" ENSG00000198910 "L1 cell adhesion molecule" P32004 X 153861514-153886173 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Differentiation, Neurogenesis" "Developmental protein" "Disease variant, Hereditary spastic paraplegia, Hirschsprung disease, Intellectual disability, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 133.9;intestine: 47.5" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 85.1;Brain excitatory neurons: 32.9;Brain inhibitory neurons: 25.3;Melanocytes: 47.9;Other brain neurons: 44.3;Renal collecting duct principal cells: 41.0;Retinal ganglion cells: 34.8;Retinal horizontal cells: 20.0;Schwann cells: 186.8" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 114.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 288.6" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Skeletal muscle - Fibroblasts, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010896 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 13000000 "Cluster 27: Cerebellum - Synaptic function" "Cluster 1: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 61: Schwann cells & Melanocytes - Mixed function" 8 "Nucleoplasm, Plasma membrane" "CAB010896: " "unprognostic (5.60e-2)" "unprognostic (3.02e-3)" "unprognostic (1.12e-1)" "unprognostic (2.95e-2)" "unprognostic (1.88e-1)" "unprognostic (5.01e-2)" "unprognostic (3.49e-2)" "unprognostic (3.43e-2)" "unprognostic (8.82e-3)" "unprognostic (3.16e-2)" "validated prognostic unfavorable (7.43e-6)" "validated prognostic unfavorable (1.01e-4)" "unprognostic (1.68e-3)" "unprognostic (1.34e-1)" "potential prognostic unfavorable (5.33e-4)" "unprognostic (1.98e-1)" "unprognostic (1.16e-3)" "unprognostic (1.83e-1)" "unprognostic (1.87e-1)" "unprognostic (6.44e-2)" "unprognostic (2.94e-2)" "unprognostic (2.60e-3)" "unprognostic (8.42e-2)" "unprognostic (9.50e-2)" "unprognostic (7.11e-3)" "unprognostic (1.03e-1)" "unprognostic (3.05e-1)" "unprognostic (2.62e-1)" "unprognostic (3.16e-3)" L1TD1 "ECAT11, FLJ10884" ENSG00000240563 "LINE1 type transposase domain containing 1" Q5T7N2 1 62194849-62212328 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 5.0;lymphoid tissue: 4.4;placenta: 10.9;testis: 5.4" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 162.1;Differentiating spermatogonia: 20.2;Extravillous trophoblasts: 29.4;Goblet cells: 19.0;Migrating cytotrophoblasts: 58.9;Peritubular myoid cells: 18.8;Syncytiotrophoblasts: 24.6;Tuft cells: 57.6;Undifferentiated spermatogonia: 129.9" "Cell type enhanced" "Detected in many" "pericyte: 4.3" "Cancer enriched" "Detected in some" 13 "Testicular Germ Cell Tumor (TCGA): 201.1" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 13 "non-classical monocyte: 5.1" "Lineage enriched" "Detected in single" 21 "monocytes: 5.1" "Cancer enriched" "Detected in some" 5 "testis cancer: 176.1" "Not detected" "Not detected" "HPA028501, HPA030064" Enhanced Vesicles NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 2: Neurons - Nucleosome" "Cluster 34: Testis cancer - Unknown function" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 1 Vesicles "HPA028501: , HPA030064: " "unprognostic (8.78e-2)" "unprognostic (3.70e-1)" "unprognostic (3.69e-2)" "unprognostic (1.05e-1)" "unprognostic (3.81e-2)" "unprognostic (1.74e-2)" "unprognostic (4.09e-1)" "unprognostic (4.63e-2)" L2HGDH "C14orf160, FLJ12618" ENSG00000087299 "L-2-hydroxyglutarate dehydrogenase" Q9H9P8 14 50237563-50312229 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 18.3" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 211.2;Proximal tubule cells: 118.2;Rod photoreceptor cells: 157.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 8.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065409, HPA069708" Approved Enhanced Mitochondria NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 76: Non-specific - Metabolism" "Cluster 31: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 79: Photoreceptor cells - Phototransduction" Mitochondria "HPA065409: , HPA069708: " "unprognostic (4.65e-2)" "unprognostic (1.12e-1)" "unprognostic (2.91e-1)" "unprognostic (2.52e-3)" "unprognostic (5.04e-3)" "unprognostic (4.80e-2)" "unprognostic (5.99e-2)" "unprognostic (1.40e-3)" "unprognostic (1.97e-2)" "unprognostic (1.01e-3)" "validated prognostic favorable (3.20e-6)" "validated prognostic favorable (1.82e-4)" "unprognostic (1.13e-2)" "unprognostic (4.06e-2)" "unprognostic (3.83e-2)" "unprognostic (1.07e-2)" "unprognostic (1.66e-2)" "unprognostic (9.57e-3)" "unprognostic (1.35e-2)" "unprognostic (2.95e-2)" "unprognostic (2.85e-1)" "unprognostic (2.45e-1)" "unprognostic (2.17e-1)" "unprognostic (1.02e-1)" "unprognostic (4.49e-3)" "unprognostic (2.10e-1)" "unprognostic (2.10e-2)" "unprognostic (3.89e-1)" "unprognostic (4.95e-2)" "unprognostic (6.87e-2)" "unprognostic (1.10e-1)" L3HYPDH "C14orf149, FLJ25436" ENSG00000126790 "Trans-L-3-hydroxyproline dehydratase" Q96EM0 14 59460363-59484408 "Enzymes, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 54.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056694 Approved Uncertain Vesicles NA NA 28000 "Cluster 33: Non-specific - ATP binding" "Cluster 75: Ovary - Mixed function" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 7: Liver cancer - Metabolism" "Cluster 89: Adipocytes - Lipid metabolism" 7 Vesicles "HPA056694: " "unprognostic (1.88e-2)" "unprognostic (2.18e-1)" "unprognostic (2.23e-1)" "unprognostic (1.61e-2)" "unprognostic (1.84e-1)" "unprognostic (1.01e-1)" "unprognostic (3.18e-2)" "unprognostic (6.06e-3)" "unprognostic (2.24e-3)" "unprognostic (1.13e-1)" "unprognostic (4.48e-2)" "unprognostic (7.48e-2)" "unprognostic (1.10e-1)" "unprognostic (3.49e-2)" "unprognostic (1.32e-1)" "unprognostic (2.92e-2)" "unprognostic (2.07e-1)" "unprognostic (6.42e-2)" "unprognostic (4.56e-1)" "unprognostic (4.21e-1)" "unprognostic (1.95e-2)" "unprognostic (1.04e-1)" "unprognostic (8.05e-2)" "unprognostic (3.51e-1)" "unprognostic (6.63e-2)" "unprognostic (6.66e-2)" "unprognostic (1.73e-1)" "unprognostic (6.78e-2)" "unprognostic (1.10e-1)" L3MBTL1 "dJ138B7.3, DKFZp586P1522, KIAA0681, L3MBTL, ZC2HC3" ENSG00000185513 "L3MBTL histone methyl-lysine binding protein 1" Q9Y468 20 43489442-43550954 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 13.5" "Cell type enhanced" "Detected in some" "Astrocytes: 23.8;Bergmann glia: 24.0;Brain excitatory neurons: 30.0;Brain inhibitory neurons: 31.0;Choroid plexus epithelial cells: 22.8;Distal convoluted tubule cells: 25.2;Ependymal cells: 17.5;Loop of henle epithelial cells: 22.7;Microglia: 14.8;Oligodendrocyte progenitor cells: 31.3;Oligodendrocytes: 34.5;Other brain neurons: 30.5;Papillary tip epithelial cells: 17.5;Podocytes: 24.8;Proximal tubule cells: 22.1;Renal collecting duct intercalated cells: 23.4;Renal collecting duct principal cells: 24.0;Renal connecting tubule cells: 19.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "testis cancer: 4.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA059648 Supported "Nucleoplasm,Nuclear bodies,Midbody ring" Yes NA "Cluster 64: Non-specific - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 102: Non-specific - Mixed function" 40 Nucleoplasm "Nuclear bodies, Midbody ring" "HPA059648: " "unprognostic (1.38e-1)" "unprognostic (1.14e-2)" "unprognostic (8.69e-3)" "unprognostic (2.04e-1)" "unprognostic (1.82e-3)" "unprognostic (9.53e-2)" "unprognostic (8.05e-3)" "unprognostic (7.86e-2)" "unprognostic (1.25e-1)" "unprognostic (1.09e-3)" "unprognostic (2.45e-1)" "potential prognostic unfavorable (4.30e-4)" "unprognostic (1.46e-1)" "unprognostic (3.02e-2)" "unprognostic (1.93e-1)" "unprognostic (4.75e-2)" "unprognostic (2.74e-2)" L3MBTL2 "dJ756G23.3, DKFZP761I141, H-l(3)mbt-l" ENSG00000100395 "L3MBTL histone methyl-lysine binding protein 2" Q969R5 22 41205282-41231271 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000815 Approved Nucleoplasm NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 20: Pituitary gland - Hormone signaling" "Cluster 11: White matter - Signal transduction" "Cluster 66: Non-specific - Mitochondria" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 80 Nucleoplasm "HPA000815: " "unprognostic (2.67e-2)" "unprognostic (1.10e-1)" "unprognostic (1.40e-1)" "unprognostic (2.75e-3)" "unprognostic (5.46e-2)" "unprognostic (6.88e-2)" "unprognostic (1.26e-1)" "unprognostic (1.00e-1)" "unprognostic (4.73e-2)" "unprognostic (1.56e-2)" "potential prognostic favorable (2.00e-4)" "unprognostic (2.10e-2)" "potential prognostic favorable (3.47e-4)" "potential prognostic unfavorable (3.10e-4)" "unprognostic (1.45e-1)" "unprognostic (9.08e-2)" "unprognostic (1.18e-1)" "unprognostic (4.58e-2)" "potential prognostic favorable (8.03e-4)" "unprognostic (1.40e-1)" "unprognostic (1.09e-1)" "unprognostic (1.61e-2)" "unprognostic (1.34e-1)" "unprognostic (1.23e-1)" "unprognostic (1.85e-1)" "unprognostic (9.94e-2)" "unprognostic (3.88e-1)" "unprognostic (1.86e-2)" "unprognostic (3.87e-1)" "unprognostic (1.34e-2)" "unprognostic (4.04e-2)" L3MBTL3 KIAA1798 ENSG00000198945 "L3MBTL histone methyl-lysine binding protein 3" Q96JM7 6 130013699-130141449 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 117.2;B-cells: 90.9;Choroid plexus epithelial cells: 101.9;Pituicytes/FSCs: 234.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044382, HPA053035" Approved Supported "Nucleoplasm,Nucleoli,Vesicles,Cytokinetic bridge,Primary cilium" Yes No "Cluster 14: Non-specific - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 43 "Nucleoplasm, Nucleoli" "Vesicles, Cytokinetic bridge, Primary cilium" "HPA044382: , HPA053035: " "unprognostic (2.52e-1)" "unprognostic (4.08e-1)" "unprognostic (3.59e-1)" "unprognostic (4.31e-2)" "unprognostic (1.16e-1)" "unprognostic (7.70e-3)" "unprognostic (1.79e-2)" "unprognostic (1.10e-1)" "unprognostic (3.76e-2)" "unprognostic (1.45e-2)" "potential prognostic favorable (4.65e-4)" "unprognostic (3.22e-2)" "unprognostic (1.22e-1)" "unprognostic (5.61e-3)" "unprognostic (8.99e-2)" "unprognostic (7.72e-3)" "unprognostic (1.64e-2)" "unprognostic (6.78e-2)" "unprognostic (1.38e-1)" "unprognostic (2.78e-2)" "unprognostic (7.27e-2)" "unprognostic (1.92e-2)" "unprognostic (3.79e-3)" "unprognostic (1.72e-1)" "unprognostic (1.99e-1)" "unprognostic (8.45e-2)" "potential prognostic unfavorable (6.94e-4)" "unprognostic (1.79e-2)" "unprognostic (2.20e-1)" "unprognostic (2.93e-2)" "unprognostic (6.47e-2)" L3MBTL4 "FLJ35936, HsT1031" ENSG00000154655 "L3MBTL histone methyl-lysine binding protein 4" Q8NA19 18 5954706-6415237 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Gonadotrophs: 627.6;Pituitary stem cells: 692.4;Proximal tubule cells: 964.4;Sertoli cells: 1133.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 3.6" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Rhabdoid: 7.0" "Pituitary gland - Undifferentiated cells (Pituitary gland)" "Not detected" "Not detected" "HPA064194, HPA069042" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 57: Testis - Spermatogenesis" "Cluster 11: White matter - Signal transduction" "Cluster 11: Neuronal - Sensory perception" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 2 "Nucleoplasm, Vesicles" "HPA064194: , HPA069042: " "unprognostic (1.49e-2)" "unprognostic (4.91e-3)" "unprognostic (7.69e-2)" "unprognostic (6.88e-2)" "unprognostic (1.92e-1)" "unprognostic (2.24e-2)" "unprognostic (4.87e-2)" "unprognostic (4.29e-1)" "unprognostic (4.19e-2)" "unprognostic (5.18e-3)" "potential prognostic favorable (3.86e-4)" "unprognostic (1.40e-2)" "unprognostic (6.96e-2)" "unprognostic (2.00e-2)" "unprognostic (8.70e-2)" "unprognostic (6.40e-2)" "potential prognostic favorable (2.11e-4)" "unprognostic (4.21e-2)" "unprognostic (1.08e-1)" "unprognostic (2.21e-1)" "unprognostic (5.31e-2)" "unprognostic (2.83e-1)" "unprognostic (8.94e-2)" "unprognostic (2.16e-2)" "unprognostic (4.11e-2)" "unprognostic (1.06e-1)" "unprognostic (2.68e-1)" "unprognostic (2.83e-2)" "potential prognostic unfavorable (1.40e-4)" "unprognostic (1.16e-1)" LACC1 "C13orf31, FAMIN, FLJ38725" ENSG00000179630 "Laccase domain containing 1" Q8IV20 13 43879284-43893932 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Immunity, Inflammatory response, Innate immunity" "Hydrolase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Cardiomyocytes: 64.0;Epicardial cells: 18.2" "Cell type enhanced" "Detected in some" "oligodendrocyte: 6.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 3.0;eosinophil: 3.1;intermediate monocyte: 5.2;myeloid DC: 2.7;non-classical monocyte: 8.0" "Group enriched" "Detected in many" 4 "dendritic cells: 2.7;granulocytes: 3.1;monocytes: 8.0" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034228, HPA040150, HPA044211" Uncertain NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 4 "CAB034228: , HPA040150: , HPA044211: " "unprognostic (2.49e-2)" "unprognostic (3.12e-1)" "unprognostic (1.57e-1)" "unprognostic (4.61e-2)" "unprognostic (7.81e-3)" "unprognostic (1.62e-2)" "unprognostic (6.39e-2)" "unprognostic (5.68e-2)" "unprognostic (4.40e-2)" "potential prognostic favorable (5.12e-7)" "unprognostic (1.24e-2)" "potential prognostic favorable (1.57e-4)" "unprognostic (1.06e-2)" "unprognostic (1.03e-2)" "unprognostic (1.07e-2)" "unprognostic (1.18e-1)" "unprognostic (5.26e-2)" "unprognostic (1.24e-3)" "unprognostic (1.61e-3)" "unprognostic (1.20e-1)" "unprognostic (2.77e-1)" "unprognostic (2.78e-1)" "unprognostic (3.74e-1)" "unprognostic (7.48e-2)" "unprognostic (2.69e-2)" "unprognostic (1.18e-1)" "unprognostic (5.65e-3)" "unprognostic (6.71e-2)" "unprognostic (2.62e-1)" LACRT LACRITIN ENSG00000135413 Lacritin Q9GZZ8 12 54630811-54634895 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 16 "salivary gland: 12.4" "Group enriched" "Detected in some" 8 "Lacrimal acinar cells: 158.5;Neutrophils: 52.5;Salivary acinar cells: 168.5" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 219 "Breast Invasive Carcinoma (TCGA): 43.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Eccrine sweat gland cells" "Secreted to digestive system" "No annotated function" NA NA 330000 "Cluster 82: Salivary gland - Secretion" "Cluster 27: Breast cancer - Unknown function" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 10 "unprognostic (1.63e-1)" "unprognostic (1.85e-1)" LACTB "FLJ14902, MRPL56" ENSG00000103642 "Lactamase beta" P83111 15 63121833-63142061 "Enzymes, Essential proteins, Predicted intracellular proteins" "Lipid metabolism" "Hydrolase, Protease" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 151.9;Mast cells: 128.9;monocytes: 152.8;Neutrophils: 183.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Macrophages, Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036361, HPA036362" Supported Supported "Nuclear membrane,Mitotic chromosome,Mitochondria,Cytosol" Yes NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 72: Neuronal - Signal transduction" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 31 Mitochondria "Nuclear membrane, Mitotic chromosome, Cytosol" "HPA036361: , HPA036362: " "unprognostic (1.24e-1)" "unprognostic (2.15e-1)" "unprognostic (1.07e-1)" "unprognostic (5.25e-2)" "unprognostic (9.00e-2)" "unprognostic (2.46e-2)" "unprognostic (1.56e-2)" "unprognostic (1.65e-1)" "unprognostic (2.56e-2)" "potential prognostic unfavorable (6.58e-4)" "potential prognostic favorable (6.22e-6)" "unprognostic (1.60e-1)" "unprognostic (2.70e-2)" "unprognostic (2.17e-1)" "unprognostic (2.92e-2)" "unprognostic (3.61e-2)" "unprognostic (1.52e-1)" "unprognostic (1.12e-1)" "unprognostic (1.17e-3)" "unprognostic (6.55e-3)" "unprognostic (1.49e-1)" "unprognostic (1.11e-2)" "unprognostic (1.14e-2)" "unprognostic (1.61e-2)" "unprognostic (4.88e-2)" "unprognostic (1.01e-1)" "unprognostic (7.46e-2)" "unprognostic (1.53e-1)" "unprognostic (1.50e-1)" "unprognostic (4.60e-2)" "unprognostic (1.41e-1)" LACTB2 CGI-83 ENSG00000147592 "Lactamase beta 2" Q53H82 8 70635318-70669185 "Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 89.6" "Cell type enhanced" "Detected in many" "Early spermatids: 251.2;Late primary spermatocytes: 666.3;Tuft cells: 172.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044391, HPA053040" Enhanced Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 93000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 76: Non-specific - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 8 Cytosol "Nucleoplasm, Golgi apparatus" "HPA044391: , HPA053040: " "unprognostic (3.89e-1)" "unprognostic (8.77e-3)" "unprognostic (5.86e-3)" "unprognostic (6.41e-2)" "unprognostic (2.52e-1)" "unprognostic (1.71e-2)" "unprognostic (1.52e-1)" "potential prognostic unfavorable (6.66e-4)" "unprognostic (2.75e-2)" "unprognostic (2.26e-3)" "potential prognostic favorable (3.04e-6)" "unprognostic (4.20e-2)" "unprognostic (1.92e-1)" "unprognostic (3.21e-2)" "unprognostic (3.88e-2)" "unprognostic (9.92e-3)" "unprognostic (2.21e-1)" "unprognostic (3.01e-1)" "unprognostic (2.87e-1)" "unprognostic (3.21e-2)" "unprognostic (6.56e-2)" "unprognostic (4.07e-3)" "unprognostic (1.69e-2)" "unprognostic (1.94e-1)" "unprognostic (2.18e-2)" "unprognostic (6.49e-2)" "unprognostic (7.99e-2)" "unprognostic (2.28e-1)" "unprognostic (1.89e-1)" "unprognostic (3.57e-1)" "unprognostic (1.13e-2)" LACTBL1 ENSG00000215906 "Lactamase beta like 1" 1 22953043-22972866 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 18 "retina: 3.6" "Cell type enriched" "Detected in some" 8 "Retinal bipolar cells: 33.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA066810 Approved "Nuclear bodies" NA NA "Cluster 42: Retina - Visual perception" "Cluster 1: Neuronal - Visual perception" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "Nuclear bodies" "HPA066810: " LAD1 ENSG00000159166 "Ladinin 1" O00515 1 201380833-201399915 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 349.5;skin 1: 207.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 38.8;Enterocytes: 33.7;Esophageal apical cells: 126.5;Esophageal basal cells: 61.8;Esophageal suprabasal cells: 110.5;Ocular epithelial cells: 41.4;Oocytes: 36.8;Pancreatic duct cells: 35.7;Suprabasal keratinocytes: 92.6;Tuft cells: 46.1;Urothelial cells: 49.6" "Cell type enriched" "Detected in single" 22 "mammillary body: 2.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 257.9" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Skin - Keratinocyte (other)" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA007256, HPA028732" Enhanced Enhanced "Actin filaments" "Secreted to extracellular matrix" "No annotated function" NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 6 "Actin filaments" "HPA007256: , HPA028732: " "unprognostic (1.87e-1)" "unprognostic (5.47e-2)" "unprognostic (1.27e-1)" "unprognostic (9.79e-2)" "unprognostic (6.27e-2)" "unprognostic (1.56e-2)" "unprognostic (1.85e-1)" "unprognostic (2.36e-2)" "unprognostic (6.63e-3)" "unprognostic (2.98e-2)" "unprognostic (1.13e-1)" "unprognostic (5.14e-2)" "unprognostic (1.47e-1)" "potential prognostic unfavorable (7.06e-4)" "unprognostic (1.18e-2)" "unprognostic (4.42e-1)" "unprognostic (1.38e-2)" "unprognostic (5.10e-2)" "unprognostic (3.40e-1)" "unprognostic (8.19e-3)" "unprognostic (3.21e-2)" "unprognostic (1.45e-1)" "unprognostic (1.45e-1)" "unprognostic (2.30e-2)" "unprognostic (4.49e-2)" "unprognostic (1.48e-2)" "unprognostic (2.49e-1)" "unprognostic (1.19e-1)" "unprognostic (4.71e-2)" LAG3 CD223 ENSG00000089692 "Lymphocyte activating 3" P18627 12 6772512-6778455 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 12.9;lymphoid tissue: 22.2;ovary: 18.0" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 15.5;Breast secretory cells: 24.5;Hofbauer cells: 27.7;Leydig cells: 38.6;Neuroendocrine cells: 14.2;Ovarian stromal cells: 27.9;Peritubular myoid cells: 69.4;T-cells: 55.0" "Cell type enriched" "Detected in single" 39 "leukocyte: 37.5" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 8 "choroid plexus: 8.5" "Immune cell enhanced" "Detected in many" "gdT-cell: 12.6;MAIT T-cell: 10.0;memory CD8 T-cell: 11.0" "Lineage enriched" "Detected in single" 49 "T-cells: 12.6" "Cancer enhanced" "Detected in some" "lymphoma: 8.0" "Adrenal gland - T-cells, Breast - T-cells, Stomach - Fibroblasts, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB002301, HPA013967" Enhanced "Intracellular and membrane" Immunity NA NA 8700 "Cluster 1: T-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 36: Choroid plexus - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 9: T-cells - Adaptive immunity: Regulation" 1 "CAB002301: , HPA013967: " "unprognostic (9.77e-2)" "unprognostic (1.23e-1)" "unprognostic (2.40e-1)" "unprognostic (1.50e-3)" "unprognostic (1.46e-1)" "unprognostic (2.28e-3)" "unprognostic (5.36e-3)" "unprognostic (2.80e-2)" "unprognostic (1.29e-1)" "unprognostic (1.16e-3)" "unprognostic (3.19e-1)" "unprognostic (3.96e-3)" "unprognostic (6.29e-2)" "unprognostic (7.84e-2)" "unprognostic (1.90e-3)" "unprognostic (3.94e-1)" "unprognostic (4.63e-2)" "potential prognostic favorable (3.09e-4)" "unprognostic (1.50e-1)" "unprognostic (1.62e-1)" "unprognostic (9.68e-2)" "unprognostic (1.78e-1)" "unprognostic (1.43e-1)" "unprognostic (5.45e-3)" "unprognostic (3.94e-2)" "unprognostic (2.57e-1)" "unprognostic (2.21e-2)" "unprognostic (1.39e-1)" LAGE3 "CVG5, DXS9879E, DXS9951E, ESO3, ITBA2, Pcc1" ENSG00000196976 "L antigen family member 3" Q14657 X 154477775-154479281 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "tRNA processing" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 160.2;Extravillous trophoblasts: 140.5;Hofbauer cells: 185.6;Megakaryocytes: 148.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036122, HPA036123" Approved Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 78: Brain - Neuronal signaling" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 97: Non-specific - Cellular respiration" 63 Nucleoplasm "Nuclear bodies" "HPA036122: , HPA036123: " "unprognostic (4.38e-2)" "unprognostic (5.61e-2)" "unprognostic (6.80e-2)" "potential prognostic favorable (6.95e-4)" "unprognostic (3.15e-2)" "unprognostic (9.10e-3)" "unprognostic (3.02e-2)" "unprognostic (2.97e-1)" "unprognostic (1.88e-1)" "unprognostic (4.10e-3)" "unprognostic (1.77e-3)" "potential prognostic unfavorable (1.90e-5)" "potential prognostic unfavorable (5.82e-6)" "validated prognostic unfavorable (3.56e-4)" "validated prognostic unfavorable (1.67e-4)" "unprognostic (1.13e-1)" "unprognostic (8.83e-2)" "unprognostic (1.23e-1)" "unprognostic (3.06e-1)" "unprognostic (1.17e-1)" "unprognostic (2.52e-1)" "unprognostic (8.76e-3)" "unprognostic (5.80e-2)" "unprognostic (9.76e-2)" "unprognostic (9.46e-2)" "unprognostic (6.11e-2)" "unprognostic (3.65e-2)" "unprognostic (8.01e-2)" "unprognostic (5.77e-2)" "unprognostic (3.24e-1)" "unprognostic (1.64e-2)" LAIR1 "CD305, LAIR-1" ENSG00000167613 "Leukocyte associated immunoglobulin like receptor 1" Q6GTX8 19 54351384-54370558 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 27.1;lymphoid tissue: 44.5" "Cell type enriched" "Detected in some" 5 "Microglia: 84.6" "Group enriched" "Detected in some" 33 "central nervous system macrophage: 108.8;leukocyte: 39.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Leukemia: 4.3;Myeloma: 2.3" "Adipose subcutaneous - Macrophages, Adrenal gland - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Lung - Macrophages, Minor Salivary Gland - Macrophages, Pituitary gland - Macrophages, Skeletal muscle - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in all" HPA011155 Enhanced Supported "Plasma membrane" NA NA 220000 "Cluster 29: Non-specific - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 6 "Plasma membrane" "HPA011155: " "unprognostic (1.88e-2)" "unprognostic (4.83e-2)" "unprognostic (1.82e-1)" "unprognostic (4.84e-3)" "unprognostic (6.56e-3)" "unprognostic (1.05e-1)" "unprognostic (2.84e-1)" "unprognostic (1.31e-1)" "unprognostic (1.24e-2)" "unprognostic (9.98e-2)" "unprognostic (2.97e-2)" "unprognostic (1.16e-1)" "unprognostic (8.67e-3)" "unprognostic (3.81e-1)" "unprognostic (8.78e-2)" "unprognostic (3.53e-1)" "unprognostic (2.04e-1)" "unprognostic (2.66e-3)" "unprognostic (4.00e-2)" "potential prognostic favorable (8.76e-4)" "unprognostic (1.39e-2)" "unprognostic (1.05e-2)" "unprognostic (2.08e-2)" LAIR2 "CD306, LAIR-2" ENSG00000167618 "Leukocyte associated immunoglobulin like receptor 2" Q6ISS4 19 54497879-54510687 "CD markers, Predicted intracellular proteins, Predicted secreted proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 1.5;pituitary gland: 2.6" "Cell type enriched" "Detected in some" 23 "Extravillous trophoblasts: 967.4" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 1.6;leukocyte: 5.8" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 9 "gdT-cell: 14.0;memory CD4 T-cell: 13.8;memory CD8 T-cell: 19.6;naive CD8 T-cell: 13.3;T-reg: 49.6" "Lineage enriched" "Detected in many" 40 "T-cells: 49.6" "Cancer enhanced" "Detected in single" "Rhabdoid: 1.4" "Testis - Late spermatids" "Secreted to blood" Receptor NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 5 "unprognostic (1.15e-1)" "unprognostic (6.90e-3)" "unprognostic (2.08e-1)" "unprognostic (1.64e-1)" "unprognostic (8.77e-3)" "unprognostic (1.82e-1)" "unprognostic (1.81e-1)" "unprognostic (1.57e-1)" "unprognostic (2.30e-3)" LALBA "HAMLET, LYZG, LYZL7" ENSG00000167531 "Lactalbumin alpha" P00709 12 48567684-48570066 "Cancer-related genes, Metabolic proteins, Predicted secreted proteins" "Lactose biosynthesis" "Milk protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 919 "breast: 2026.3" "Cell type enriched" "Detected in some" 166775 "Breast lactating cells: 483428.6" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 987 "Breast Invasive Carcinoma (TCGA): 98.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 45 "breast cancer: 2.1;Rhabdoid: 6.8" "Testis - Sertoli cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB026343, HPA029855, HPA029856" Enhanced "Secreted in female reproductive system" Other NA NA 180000 "Cluster 55: Breast - Lactation" "Cluster 3: Rhabdoid - Membrane components" "Cluster 4: Breast lactating luminal cells - Lactation" 1 "CAB026343: , HPA029855: , HPA029856: " "unprognostic (6.38e-1)" "unprognostic (2.98e-1)" LAMA1 LAMA ENSG00000101680 "Laminin subunit alpha 1" P25391 18 6941742-7117797 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 3.1;ovary: 3.1;testis: 5.5" "Cell type enhanced" "Detected in many" "Astrocytes: 214.6;Colonocytes: 126.5;Distal convoluted tubule cells: 161.4;Ependymal cells: 220.6;Epicardial cells: 125.1;Epididymal basal cells: 118.3;Epididymal efferent duct ciliated cells: 133.0;Granulosa cells: 120.8;Loop of henle epithelial cells: 155.1;Pituitary stem cells: 152.1;Salivary myoepithelial cells: 137.6;Sertoli cells: 612.3" "Cell type enhanced" "Detected in many" "astrocyte: 293.5;ependymal cell: 223.9" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 10.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 34.9" "Testis - Sertoli cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" CAB010179 Enhanced "Secreted to extracellular matrix" "Cell adhesion" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 19: Astrocytes - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 2 "CAB010179: " "unprognostic (1.11e-1)" "unprognostic (2.50e-2)" "unprognostic (2.56e-2)" "unprognostic (1.65e-2)" "unprognostic (3.24e-2)" "unprognostic (4.47e-3)" "unprognostic (8.27e-3)" "unprognostic (7.11e-2)" "unprognostic (7.17e-2)" "unprognostic (1.69e-1)" "unprognostic (1.67e-2)" "unprognostic (3.26e-1)" "unprognostic (1.56e-3)" "unprognostic (3.00e-1)" "unprognostic (9.25e-2)" "unprognostic (2.63e-1)" "unprognostic (4.66e-2)" "unprognostic (1.16e-1)" LAMA2 LAMM ENSG00000196569 "Laminin subunit alpha 2" P24043 6 128883138-129516566 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Congenital muscular dystrophy, Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 138.5" "Cell type enhanced" "Detected in many" "Bergmann glia: 2924.4;Cardiomyocytes: 4106.9;Epicardial cells: 1248.5;Fibro-adipogenic progenitors: 4424.7;Fibroblasts: 2897.5;Leydig cells: 3129.3;Myosatellite cells: 3009.5;Peritubular myoid cells: 1698.9;Pituicytes/FSCs: 4536.1;Thymic myoid cells: 2915.0" "Group enriched" "Detected in all" 10 "Bergmann glia: 3075.9;fibroblast: 6196.9;pericyte: 4582.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "MAIT T-cell: 1.1" "Lineage enriched" "Detected in single" 5 "T-cells: 1.1" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Kidney - Fibroblasts, Minor Salivary Gland - Macrophages, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB040310, CAB078182" Enhanced "Secreted to extracellular matrix" "Cell adhesion" NA NA 46000000 "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 8: Immune cells - Immune response" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" "CAB040310: , CAB078182: " "unprognostic (5.69e-2)" "unprognostic (2.25e-1)" "unprognostic (1.19e-1)" "unprognostic (4.15e-1)" "unprognostic (1.02e-1)" "unprognostic (1.24e-1)" "unprognostic (3.40e-1)" "potential prognostic unfavorable (3.42e-4)" "unprognostic (2.72e-1)" "unprognostic (1.05e-1)" "unprognostic (2.79e-2)" "unprognostic (3.47e-1)" "unprognostic (1.69e-3)" "unprognostic (5.23e-2)" "unprognostic (1.06e-3)" "unprognostic (4.82e-3)" "unprognostic (6.68e-2)" "unprognostic (2.57e-2)" "unprognostic (2.74e-2)" "unprognostic (2.52e-2)" "unprognostic (6.76e-2)" "unprognostic (1.03e-1)" "unprognostic (2.76e-1)" "unprognostic (1.02e-1)" "unprognostic (2.40e-3)" "unprognostic (1.09e-2)" "unprognostic (7.66e-2)" "unprognostic (1.11e-3)" "unprognostic (6.56e-2)" "unprognostic (2.89e-3)" "unprognostic (1.44e-1)" LAMA3 "BM600-150kDa, epiligrin, kalinin-165kDa, LAMNA, nicein-150kDa" ENSG00000053747 "Laminin subunit alpha 3" Q16787 18 23689453-23956222 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 1004.7;Colonocytes: 797.6;Endometrial secretory cells: 511.4;Epididymal basal cells: 2325.5;Foveolar cells: 544.5;Medullary thymic epithelial cells: 343.2;Salivary myoepithelial cells: 409.9" "Cell type enriched" "Detected in many" 4 "endothelial cell: 542.0" "Cancer enhanced" "Detected in all" "Head and Neck Squamous Cell Carcinoma (TCGA): 146.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 161.4" "Lung - Alveolar cells type 1, Prostate - Smooth muscle cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA009309, CAB010757" Uncertain Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" "Cell adhesion" NA NA 1300000 "Cluster 11: Esophagus - Basic cellular processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 2 "Endoplasmic reticulum" "CAB010757: , HPA009309: " "unprognostic (5.61e-2)" "unprognostic (1.40e-3)" "unprognostic (2.59e-2)" "unprognostic (8.30e-3)" "unprognostic (1.92e-2)" "unprognostic (3.15e-1)" "unprognostic (3.87e-2)" "unprognostic (2.79e-2)" "unprognostic (6.38e-2)" "unprognostic (4.14e-3)" "unprognostic (2.69e-2)" "unprognostic (1.59e-2)" "unprognostic (6.96e-2)" "unprognostic (6.20e-2)" "unprognostic (6.81e-3)" "potential prognostic unfavorable (7.33e-5)" "unprognostic (2.70e-1)" "unprognostic (2.24e-1)" "unprognostic (7.48e-3)" "unprognostic (9.83e-2)" "unprognostic (2.43e-1)" "potential prognostic unfavorable (5.11e-6)" "unprognostic (9.37e-3)" "unprognostic (1.93e-1)" "unprognostic (2.17e-1)" "unprognostic (5.50e-3)" "unprognostic (2.29e-1)" "unprognostic (3.78e-1)" "unprognostic (1.14e-2)" "unprognostic (2.19e-1)" "unprognostic (3.17e-1)" LAMA4 LAMA3 ENSG00000112769 "Laminin subunit alpha 4" Q16363 6 112107931-112254939 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 163.3" "Cell type enhanced" "Detected in many" "Adipocytes: 2273.6;Bergmann glia: 515.0;Cardiomyocytes: 272.2;Epicardial cells: 420.7;Fibro-adipogenic progenitors: 527.1;Leydig cells: 526.8;Lymphatic endothelial cells: 375.2;Mesothelial cells: 1031.2;Pericytes: 379.1;Pituicytes/FSCs: 649.3;Smooth muscle cells: 401.6" "Cell type enhanced" "Detected in all" "Bergmann glia: 540.3;fibroblast: 897.8;pericyte: 384.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 113.3" "Breast - Endothelial cells, Liver - Hepatic stellate cells, Lung - Fibroblasts_1, Prostate - Smooth muscle cells, Skeletal muscle - Fibroblasts, Testis - Peritubular cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015693, CAB078156" Enhanced Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" "Cell adhesion" NA NA 500000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 19: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 89: Adipocytes - Lipid metabolism" 3 "Plasma membrane, Cytosol" "CAB078156: , HPA015693: " "unprognostic (2.64e-2)" "unprognostic (5.84e-2)" "unprognostic (3.33e-1)" "potential prognostic unfavorable (3.59e-4)" "unprognostic (9.31e-2)" "unprognostic (3.39e-1)" "unprognostic (8.40e-2)" "unprognostic (1.01e-1)" "unprognostic (2.01e-1)" "unprognostic (1.70e-3)" "unprognostic (1.86e-2)" "unprognostic (8.26e-2)" "unprognostic (1.23e-1)" "unprognostic (1.32e-2)" "unprognostic (1.45e-1)" "unprognostic (1.66e-1)" "unprognostic (1.44e-3)" "unprognostic (6.20e-2)" "unprognostic (1.99e-1)" "unprognostic (3.20e-3)" "unprognostic (1.13e-2)" "unprognostic (2.21e-2)" "unprognostic (1.02e-1)" "unprognostic (1.37e-2)" "unprognostic (3.92e-1)" "unprognostic (1.15e-2)" "unprognostic (2.84e-2)" "unprognostic (3.85e-3)" "unprognostic (1.41e-1)" "unprognostic (8.71e-3)" "unprognostic (1.89e-1)" LAMA5 ENSG00000130702 "Laminin subunit alpha 5" O15230 20 62307955-62367312 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 129.4;Cytotrophoblasts: 146.2;Endometrial glandular cells: 103.2;Endometrial luminal cells: 103.6;Podocytes: 157.7;Prostatic hillock cells: 127.0;Respiratory basal cells: 118.0;Vascular smooth muscle cells: 104.4" "Cell type enhanced" "Detected in all" "vascular associated smooth muscle cell: 109.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Endothelial cells, Pituitary gland - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA058389, CAB078157" Enhanced Uncertain Vesicles "Secreted to extracellular matrix" "Cell adhesion" NA NA 1700000 "Cluster 64: Non-specific - Transcription" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 27 Vesicles "CAB078157: , HPA058389: " "unprognostic (8.21e-2)" "unprognostic (1.01e-1)" "unprognostic (5.84e-2)" "unprognostic (3.90e-2)" "unprognostic (1.03e-1)" "unprognostic (3.16e-3)" "unprognostic (1.84e-1)" "unprognostic (6.55e-2)" "unprognostic (9.56e-2)" "unprognostic (8.10e-2)" "unprognostic (1.75e-1)" "unprognostic (4.49e-2)" "unprognostic (1.71e-1)" "unprognostic (8.60e-3)" "unprognostic (4.52e-3)" "unprognostic (6.68e-2)" "unprognostic (1.98e-1)" "unprognostic (2.58e-1)" "unprognostic (1.07e-2)" "unprognostic (5.40e-2)" "unprognostic (7.00e-2)" "unprognostic (4.34e-2)" "potential prognostic unfavorable (3.87e-5)" "unprognostic (1.12e-1)" "unprognostic (3.10e-1)" "unprognostic (9.56e-3)" "unprognostic (2.42e-1)" "unprognostic (6.13e-2)" "unprognostic (5.76e-2)" "unprognostic (5.31e-2)" "unprognostic (1.73e-1)" LAMB1 CLM ENSG00000091136 "Laminin subunit beta 1" P07942 7 107923799-108003213 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 145.0" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 295.1;Cytotrophoblasts: 250.6;Decidual stromal cells: 288.3;Distal convoluted tubule cells: 335.4;Endometrial stromal cells: 393.7;Fibro-adipogenic progenitors: 257.3;Fibroblasts: 265.5;Loop of henle epithelial cells: 245.6;Mesothelial cells: 668.3;Peritubular myoid cells: 302.8;Renal collecting duct intercalated cells: 250.5;Renal connecting tubule cells: 656.5;Schwann cells: 273.7" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 324.0;midbrain-derived inhibitory: 267.7" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 7 "choroid plexus: 54.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Skin - Macrophages, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004056, HPA004132, CAB004256" Enhanced "Secreted to extracellular matrix" "Cell adhesion" NA NA 82000000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 23: Choroid plexus - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 36 "CAB004256: , HPA004056: , HPA004132: " "unprognostic (6.75e-2)" "unprognostic (2.03e-1)" "unprognostic (1.14e-1)" "unprognostic (4.51e-2)" "unprognostic (2.59e-1)" "unprognostic (1.20e-1)" "unprognostic (1.53e-1)" "unprognostic (1.85e-1)" "unprognostic (4.54e-2)" "unprognostic (1.74e-1)" "unprognostic (2.07e-3)" "unprognostic (1.11e-1)" "unprognostic (1.76e-1)" "potential prognostic unfavorable (7.77e-4)" "unprognostic (7.48e-3)" "validated prognostic unfavorable (9.95e-4)" "validated prognostic unfavorable (2.48e-5)" "unprognostic (3.74e-2)" "unprognostic (1.43e-1)" "unprognostic (1.81e-2)" "unprognostic (2.94e-2)" "unprognostic (1.89e-1)" "unprognostic (7.52e-3)" "unprognostic (1.71e-1)" "unprognostic (3.06e-1)" "unprognostic (1.63e-1)" "unprognostic (8.18e-2)" "unprognostic (4.72e-3)" "unprognostic (3.02e-2)" "unprognostic (2.25e-2)" "unprognostic (2.37e-2)" LAMB2 "LAMS, NPHS5" ENSG00000172037 "Laminin subunit beta 2" P55268 3 49121114-49133118 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Leydig cells: 161.2;Lymphatic endothelial cells: 114.2;Peritubular myoid cells: 165.1;Vascular smooth muscle cells: 108.9" "Cell type enhanced" "Detected in many" "pericyte: 147.6;vascular associated smooth muscle cell: 117.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000053, HPA001895, HPA050033, CAB078160" Supported Approved Vesicles,Cytosol "Secreted to extracellular matrix" "Cell adhesion" NA NA 16000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 35: Non-specific - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 110: Mural cells - ECM organization" 41 Vesicles Cytosol "CAB000053: , CAB078160: , HPA001895: , HPA050033: " "unprognostic (1.14e-2)" "unprognostic (1.38e-1)" "unprognostic (7.61e-2)" "unprognostic (1.47e-2)" "unprognostic (9.87e-2)" "unprognostic (5.10e-2)" "unprognostic (2.75e-1)" "unprognostic (5.67e-3)" "unprognostic (3.55e-1)" "unprognostic (5.15e-2)" "potential prognostic favorable (2.56e-9)" "unprognostic (1.96e-3)" "unprognostic (2.23e-1)" "unprognostic (1.81e-1)" "unprognostic (6.20e-2)" "unprognostic (2.18e-2)" "unprognostic (1.29e-2)" "unprognostic (4.58e-2)" "unprognostic (5.16e-1)" "unprognostic (3.70e-2)" "unprognostic (8.51e-2)" "unprognostic (2.20e-2)" "unprognostic (2.04e-1)" "unprognostic (1.79e-1)" "unprognostic (2.61e-2)" "potential prognostic favorable (3.46e-4)" "unprognostic (1.66e-1)" "unprognostic (1.21e-1)" "unprognostic (1.00e-2)" "unprognostic (6.55e-2)" "unprognostic (8.79e-2)" LAMB3 "BM600-125kDa, kalinin-140kDa, LAMNB1, nicein-125kDa" ENSG00000196878 "Laminin subunit beta 3" Q13751 1 209614870-209652425 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Amelogenesis imperfecta, Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 69.1;urinary bladder: 68.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 331.0;Basal keratinocytes: 294.5;Breast myoepithelial cells: 242.0;Endometrial glandular cells: 263.4;Endometrial secretory cells: 600.9;Epididymal basal cells: 423.6;Foveolar cells: 339.6;Ocular epithelial cells: 394.7;Prostatic hillock cells: 236.4;Salivary basal cells: 601.5;Urothelial cells: 611.5" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Head and Neck Squamous Cell Carcinoma (TCGA): 426.9" "Region enriched" "Detected in many" 7 "cerebral cortex: 41.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 438.1" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Breast myoepithelial cells, Colon - Colon enterocytes, Minor Salivary Gland - Minor salivary gland basal cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA007584, HPA008069, CAB078183" Enhanced Approved Vesicles "Secreted to extracellular matrix" "Cell adhesion" NA NA 9100 "Cluster 11: Esophagus - Basic cellular processes" "Cluster 53: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 69: Urothelial cells - Basic cellular functions" 33 Vesicles "CAB078183: , HPA007584: , HPA008069: " "unprognostic (3.34e-2)" "potential prognostic favorable (8.76e-4)" "unprognostic (2.24e-1)" "unprognostic (9.07e-3)" "unprognostic (3.73e-1)" "unprognostic (1.06e-1)" "unprognostic (4.18e-2)" "unprognostic (8.91e-2)" "unprognostic (1.49e-3)" "unprognostic (1.53e-3)" "potential prognostic unfavorable (5.44e-4)" "unprognostic (1.30e-2)" "unprognostic (3.06e-3)" "unprognostic (2.30e-1)" "unprognostic (2.85e-2)" "potential prognostic unfavorable (1.80e-4)" "unprognostic (7.26e-3)" "unprognostic (4.14e-2)" "unprognostic (2.50e-3)" "unprognostic (3.29e-1)" "unprognostic (1.09e-2)" "potential prognostic unfavorable (4.09e-4)" "unprognostic (1.76e-2)" "unprognostic (2.01e-1)" "unprognostic (3.79e-1)" "unprognostic (1.20e-2)" "unprognostic (1.68e-1)" "unprognostic (3.48e-2)" "unprognostic (1.55e-1)" "unprognostic (3.31e-2)" "unprognostic (8.88e-2)" LAMB4 ENSG00000091128 "Laminin subunit beta 4" A4D0S4 7 108023548-108130361 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "skin 1: 36.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 100.7;Cone photoreceptor cells: 20.7;Epicardial cells: 29.6;Late spermatids: 18.2;Loop of henle epithelial cells: 31.9;Mesothelial cells: 49.3;Migrating cytotrophoblasts: 28.5;Ocular epithelial cells: 18.4;Parietal cells: 19.4;Renal collecting duct intercalated cells: 19.1" "Cell type enhanced" "Detected in many" "Bergmann glia: 7.8" "Cancer enriched" "Detected in single" 9 "Kidney Chromophobe (TCGA): 5.7" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "Bladder cancer: 2.8;cervical cancer: 1.3;Uterine cancer: 2.8" "Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "HPA020242, HPA024247" Approved "Secreted to extracellular matrix" "Cell adhesion" NA NA "Cluster 37: Skin - Keratinization" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" "HPA020242: , HPA024247: " "unprognostic (1.23e-1)" "unprognostic (6.95e-2)" "unprognostic (2.65e-3)" LAMC1 LAMB2 ENSG00000135862 "Laminin subunit gamma 1" P11047 1 183023420-183145592 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 217.7" "Cell type enhanced" "Detected in many" "Adipocytes: 430.7;Epididymal basal cells: 814.0;Fibro-adipogenic progenitors: 819.4;Fibroblasts: 522.5;Pituicytes/FSCs: 454.8" "Cell type enhanced" "Detected in all" "fibroblast: 657.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "testis cancer: 422.9" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001908, HPA001909, CAB004486, CAB078163" Enhanced Uncertain "Endoplasmic reticulum,Plasma membrane" "Secreted to extracellular matrix" "Cell adhesion" NA NA 40000000 "Cluster 14: Non-specific - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 12: Non-specific - Vasculature" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 31 "Endoplasmic reticulum, Plasma membrane" "CAB004486: , CAB078163: , HPA001908: , HPA001909: " "unprognostic (1.58e-1)" "unprognostic (2.16e-1)" "unprognostic (1.13e-1)" "unprognostic (1.19e-2)" "unprognostic (2.56e-1)" "unprognostic (1.63e-2)" "unprognostic (4.26e-2)" "unprognostic (5.13e-2)" "unprognostic (8.68e-2)" "potential prognostic unfavorable (2.67e-4)" "potential prognostic favorable (5.40e-4)" "unprognostic (1.70e-1)" "potential prognostic unfavorable (9.68e-4)" "unprognostic (1.58e-2)" "unprognostic (8.09e-3)" "potential prognostic unfavorable (9.06e-4)" "unprognostic (2.25e-3)" "unprognostic (1.87e-1)" "unprognostic (3.10e-1)" "unprognostic (9.14e-2)" "unprognostic (4.41e-2)" "unprognostic (5.39e-2)" "unprognostic (4.08e-2)" "unprognostic (5.12e-1)" "unprognostic (6.54e-2)" "unprognostic (1.25e-2)" "unprognostic (1.05e-2)" "unprognostic (6.93e-3)" "unprognostic (2.05e-1)" "unprognostic (1.06e-1)" "unprognostic (3.46e-2)" LAMC2 "BM600-100kDa, EBR2, EBR2A, kalinin-105kDa, LAMB2T, LAMNB2, nicein-100kDa" ENSG00000058085 "Laminin subunit gamma 2" Q13753 1 183186238-183245127 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" Heparin-binding "Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 36.5" "Cell type enriched" "Detected in many" 6 "Epididymal basal cells: 5218.8" "Cell type enhanced" "Detected in many" "upper rhombic lip: 8.5" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 403.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 511.2" "Breast - Breast myoepithelial cells, Liver - Cholangiocytes, Pancreas - Ductal cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB004257, HPA024638, HPA046539, HPA046540, CAB078165" Enhanced Approved "Endoplasmic reticulum,Golgi apparatus" "Secreted to extracellular matrix" "Cell adhesion" No No 27000 "Cluster 13: Lung - Secretion" "Cluster 15: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 51: Secretory epithelial cells - Mixed function" 4 "Endoplasmic reticulum, Golgi apparatus" "CAB004257: , CAB078165: , HPA024638: , HPA046539: , HPA046540: " "unprognostic (1.17e-1)" "unprognostic (1.07e-2)" "unprognostic (2.25e-1)" "unprognostic (1.23e-2)" "unprognostic (9.80e-2)" "unprognostic (3.57e-1)" "unprognostic (4.63e-2)" "unprognostic (4.25e-3)" "unprognostic (2.72e-2)" "unprognostic (1.74e-1)" "unprognostic (7.78e-2)" "unprognostic (3.83e-2)" "unprognostic (4.42e-2)" "unprognostic (1.36e-1)" "potential prognostic unfavorable (5.82e-6)" "unprognostic (1.02e-2)" "unprognostic (4.56e-3)" "potential prognostic unfavorable (4.73e-6)" "unprognostic (2.32e-1)" "unprognostic (9.19e-2)" "potential prognostic unfavorable (7.41e-5)" "unprognostic (4.32e-2)" "unprognostic (3.33e-1)" "unprognostic (1.91e-1)" "unprognostic (1.09e-2)" "unprognostic (1.70e-1)" "unprognostic (2.22e-1)" "unprognostic (2.90e-1)" "unprognostic (1.09e-1)" "unprognostic (6.00e-2)" LAMC3 DKFZp434E202 ENSG00000050555 "Laminin subunit gamma 3" Q9Y6N6 9 131009174-131094473 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 45.8" "Group enriched" "Detected in many" 4 "Leydig cells: 300.6;Peritubular myoid cells: 772.4" "Group enriched" "Detected in many" 10 "fibroblast: 382.9;pericyte: 292.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 7.8;Rhabdoid: 9.2" "Kidney - Fibroblasts, Pituitary gland - Fibroblasts, Testis - Peritubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022814 Enhanced "Secreted to extracellular matrix" "Cell adhesion" NA NA 180000 "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 3: Rhabdoid - Membrane components" "Cluster 94: Gonadal somatic cells - Mixed function" 5 "HPA022814: " "unprognostic (9.83e-2)" "unprognostic (4.15e-1)" "unprognostic (1.18e-1)" "unprognostic (1.45e-1)" "unprognostic (4.39e-1)" "unprognostic (1.91e-2)" "unprognostic (7.31e-3)" "unprognostic (2.99e-2)" "unprognostic (2.91e-2)" "unprognostic (1.75e-1)" "unprognostic (2.39e-1)" "unprognostic (7.71e-2)" "potential prognostic favorable (4.97e-4)" "unprognostic (7.58e-2)" "unprognostic (2.29e-1)" "unprognostic (6.39e-3)" "unprognostic (1.26e-1)" "unprognostic (1.19e-1)" "unprognostic (1.41e-3)" "unprognostic (1.90e-1)" "potential prognostic unfavorable (6.22e-4)" "unprognostic (1.32e-1)" "unprognostic (1.81e-1)" "unprognostic (2.34e-1)" "unprognostic (3.80e-2)" "unprognostic (3.03e-1)" "unprognostic (1.96e-1)" LAMP1 CD107a ENSG00000185896 "Lysosomal associated membrane protein 1" P11279 13 113297239-113323672 "CD markers, Plasma proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 666.0;Late spermatids: 1055.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Lung - Macrophages, Pancreas - Macrophages, Spleen - Macrophages, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004260, HPA014750" Supported NA NA 51000000 "Cluster 45: Eosinophils - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 30: White matter - Myelination" "Cluster 19: Non-specific - Unknown function" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 250 "CAB004260: , HPA014750: " "unprognostic (9.63e-2)" "unprognostic (6.69e-2)" "unprognostic (2.53e-1)" "unprognostic (3.31e-2)" "unprognostic (6.14e-2)" "unprognostic (2.26e-2)" "unprognostic (1.56e-1)" "unprognostic (2.23e-1)" "unprognostic (4.00e-2)" "unprognostic (7.88e-2)" "potential prognostic favorable (1.48e-5)" "unprognostic (8.87e-2)" "unprognostic (7.15e-2)" "unprognostic (5.71e-2)" "unprognostic (7.19e-2)" "unprognostic (1.02e-1)" "unprognostic (7.93e-2)" "unprognostic (3.58e-2)" "unprognostic (2.72e-1)" "unprognostic (7.97e-2)" "unprognostic (1.16e-1)" "unprognostic (5.44e-2)" "unprognostic (2.90e-1)" "unprognostic (3.16e-1)" "unprognostic (5.87e-2)" "unprognostic (1.75e-1)" "unprognostic (4.44e-2)" "unprognostic (8.72e-2)" "unprognostic (3.42e-1)" "unprognostic (1.57e-1)" "unprognostic (3.12e-1)" LAMP2 CD107b ENSG00000005893 "Lysosomal associated membrane protein 2" P13473 X 120426148-120469365 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" Autophagy "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 611.4;Neutrophils: 799.9;Oligodendrocytes: 577.1;Syncytiotrophoblasts: 572.9" "Cell type enhanced" "Detected in all" "oligodendrocyte: 659.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 564.0" "Lineage enriched" "Detected in all" 5 "granulocytes: 564.0" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005272, HPA029100" Supported Supported "Endoplasmic reticulum,Vesicles,Plasma membrane" NA NA 37000000 "Cluster 7: Non-specific - Innate immune response" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 36: Non-specific - mRNA processing" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 29 "Endoplasmic reticulum, Vesicles, Plasma membrane" "CAB005272: , HPA029100: " "unprognostic (2.90e-1)" "unprognostic (2.21e-2)" "unprognostic (1.51e-1)" "unprognostic (2.55e-1)" "unprognostic (3.07e-3)" "unprognostic (1.31e-3)" "unprognostic (4.73e-2)" "potential prognostic unfavorable (2.14e-4)" "unprognostic (3.30e-2)" "potential prognostic unfavorable (8.29e-4)" "potential prognostic favorable (1.14e-5)" "unprognostic (1.56e-2)" "unprognostic (6.74e-2)" "unprognostic (4.02e-1)" "unprognostic (7.73e-2)" "unprognostic (1.33e-1)" "unprognostic (4.82e-3)" "unprognostic (1.32e-1)" "unprognostic (1.91e-1)" "unprognostic (4.65e-3)" "unprognostic (1.41e-1)" "unprognostic (2.33e-1)" "unprognostic (1.42e-1)" "unprognostic (6.14e-2)" "unprognostic (8.71e-2)" "unprognostic (1.18e-1)" "unprognostic (3.02e-2)" "unprognostic (3.81e-2)" "unprognostic (1.94e-1)" "unprognostic (1.38e-1)" "unprognostic (7.74e-2)" LAMP3 "CD208, DC-LAMP, DCLAMP, LAMP, TSC403" ENSG00000078081 "Lysosomal associated membrane protein 3" Q9UQV4 3 183122215-183163839 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "lung: 207.1" "Cell type enriched" "Detected in many" 4 "Alveolar cells type 2: 925.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 5.6" "Group enriched" "Detected in many" 9 "granulocytes: 5.6;T-cells: 4.8" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2, Minor Salivary Gland - Mitotic cells (Minor salivary gland), Spleen - T-cells, Testis - Early spermatids, Testis - Late spermatids" "CAB025133, HPA051467" Enhanced Enhanced Vesicles NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 13: Lung - Secretion" "Cluster 15: Non-specific - Transcription" "Cluster 55: Lymphoma - Immune response" "Cluster 81: Alveolar cells - Lung function" 32 Vesicles "CAB025133: , HPA051467: " "potential prognostic favorable (2.30e-4)" "unprognostic (5.01e-3)" "unprognostic (3.76e-2)" "unprognostic (2.11e-1)" "unprognostic (2.21e-1)" "unprognostic (2.70e-2)" "unprognostic (9.56e-3)" "unprognostic (2.98e-1)" "unprognostic (3.00e-2)" "unprognostic (1.08e-2)" "unprognostic (3.38e-2)" "unprognostic (1.27e-3)" "unprognostic (6.68e-2)" "unprognostic (2.32e-2)" "unprognostic (4.99e-2)" "unprognostic (1.08e-1)" "unprognostic (1.24e-2)" "unprognostic (4.27e-1)" "unprognostic (5.86e-3)" "unprognostic (5.75e-2)" "unprognostic (1.71e-3)" "potential prognostic unfavorable (5.75e-4)" "unprognostic (1.30e-1)" "unprognostic (3.35e-1)" "unprognostic (3.52e-1)" "unprognostic (2.60e-1)" "unprognostic (1.40e-1)" "unprognostic (1.54e-1)" "unprognostic (3.37e-2)" "unprognostic (2.49e-2)" LAMP5 "BAD-LAMP, C20orf103, dJ1119D9.3, UNC-46" ENSG00000125869 "Lysosomal associated membrane protein family member 5" Q9UJQ1 20 9514358-9530524 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 297.8" "Cell type enhanced" "Detected in some" "Bergmann glia: 92.0;Brain inhibitory neurons: 72.8;Granulosa cells: 142.7;Megakaryocytes: 30.9;Ovarian stromal cells: 65.0;pDCs: 215.6;Plasma cells: 31.2;Retinal horizontal cells: 36.1" "Cell type enhanced" "Detected in many" "LAMP5-LHX6 and Chandelier: 305.4;medium spiny neuron: 143.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 15 "plasmacytoid DC: 141.6" "Lineage enriched" "Detected in many" 31 "dendritic cells: 141.6" "Group enriched" "Detected in some" 8 "Leukemia: 56.6;Myeloma: 90.7;Neuroblastoma: 37.5" "Adrenal gland - Adrenal cortex cells, Colon - Enteric glia cells, Pituitary gland - Thyrotropes, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004802, HPA070765" Enhanced Uncertain "Mitotic spindle,Centriolar satellite,Cytosol" Yes NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 78: Brain - Neuronal signaling" "Cluster 24: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 35: Neurons - Synaptic function & neurogenesis" 1 Cytosol "Mitotic spindle, Centriolar satellite" "HPA004802: , HPA070765: " "unprognostic (4.54e-2)" "unprognostic (5.59e-2)" "unprognostic (6.16e-3)" "potential prognostic unfavorable (8.57e-4)" "unprognostic (7.09e-2)" "unprognostic (9.29e-3)" "unprognostic (2.84e-1)" "unprognostic (2.53e-1)" "unprognostic (1.43e-2)" "potential prognostic unfavorable (8.51e-4)" "unprognostic (2.65e-1)" "unprognostic (2.24e-3)" "unprognostic (2.62e-3)" "unprognostic (1.87e-1)" "unprognostic (8.52e-2)" "unprognostic (6.68e-2)" "unprognostic (1.04e-2)" "unprognostic (1.56e-1)" "unprognostic (1.35e-1)" "unprognostic (8.36e-2)" "unprognostic (2.76e-2)" "unprognostic (1.00e-1)" "unprognostic (4.47e-1)" "unprognostic (3.78e-2)" "unprognostic (5.40e-2)" "unprognostic (3.14e-3)" "unprognostic (1.29e-2)" "unprognostic (1.68e-2)" "unprognostic (7.85e-2)" LAMTOR1 "C11orf59, FLJ20625, p18, p27RF-Rho, Pdro, Ragulator1" ENSG00000149357 "Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1" Q6IAA8 11 72085895-72103297 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 630.3;Megakaryocytes: 1199.2;Platelets: 2059.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002997 Approved Uncertain "Golgi apparatus,Vesicles,Plasma membrane" NA NA 59000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 47: Platelets - Hemostasis" 109 "Golgi apparatus" "Vesicles, Plasma membrane" "HPA002997: " "unprognostic (1.84e-1)" "unprognostic (1.58e-1)" "unprognostic (4.37e-2)" "unprognostic (1.09e-1)" "unprognostic (2.94e-1)" "unprognostic (4.67e-2)" "unprognostic (1.17e-1)" "unprognostic (6.45e-3)" "unprognostic (6.22e-2)" "potential prognostic favorable (1.35e-5)" "unprognostic (2.99e-2)" "potential prognostic favorable (6.09e-4)" "validated prognostic unfavorable (5.38e-4)" "validated prognostic unfavorable (5.49e-4)" "unprognostic (1.84e-2)" "unprognostic (8.46e-3)" "unprognostic (1.51e-1)" "unprognostic (3.88e-1)" "unprognostic (1.19e-1)" "unprognostic (1.99e-1)" "unprognostic (1.54e-1)" "unprognostic (3.67e-1)" "unprognostic (8.27e-2)" "unprognostic (2.02e-1)" "unprognostic (3.85e-1)" "unprognostic (1.27e-2)" "unprognostic (1.27e-1)" "unprognostic (4.69e-2)" "unprognostic (1.20e-1)" "unprognostic (2.63e-1)" LAMTOR2 "ENDAP, MAPBPIP, MAPKSP1AP, p14, Ragulator2, ROBLD3" ENSG00000116586 "Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2" Q9Y2Q5 1 156054782-156058506 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 401.6;Esophageal suprabasal cells: 364.9;Hepatocytes: 361.0;Hofbauer cells: 576.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004126 Approved Approved Nucleoplasm,Vesicles No No 8000 "Cluster 29: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 45: Non-specific - Nuclear processes" "Cluster 97: Non-specific - Cellular respiration" 49 "Nucleoplasm, Vesicles" "HPA004126: " "unprognostic (3.46e-3)" "unprognostic (2.85e-1)" "unprognostic (3.28e-2)" "unprognostic (9.06e-2)" "unprognostic (4.43e-2)" "unprognostic (3.96e-2)" "unprognostic (2.92e-1)" "unprognostic (1.17e-1)" "unprognostic (8.97e-3)" "potential prognostic unfavorable (1.78e-7)" "unprognostic (8.96e-3)" "unprognostic (2.53e-2)" "unprognostic (1.79e-2)" "unprognostic (6.71e-2)" "unprognostic (1.74e-1)" "unprognostic (2.07e-1)" "unprognostic (2.08e-1)" "unprognostic (1.25e-1)" "unprognostic (5.18e-2)" "unprognostic (6.51e-2)" "unprognostic (1.24e-1)" "unprognostic (5.58e-2)" "unprognostic (1.21e-2)" "unprognostic (2.26e-2)" "unprognostic (7.63e-2)" "unprognostic (2.94e-1)" "unprognostic (3.33e-2)" "unprognostic (4.43e-1)" "unprognostic (2.10e-1)" "unprognostic (9.91e-2)" LAMTOR3 "MAP2K1IP1, MAPBP, MAPKSP1, MP1, Ragulator3" ENSG00000109270 "Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3" Q9UHA4 4 99878336-99894428 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 320.5;Neutrophils: 183.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026858 Supported NA NA 12000 "Cluster 35: Neutrophils - Protein binding" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 1: Neurons - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 46 "HPA026858: " "unprognostic (1.54e-2)" "unprognostic (2.25e-1)" "unprognostic (6.88e-2)" "unprognostic (1.64e-1)" "unprognostic (2.82e-3)" "potential prognostic unfavorable (7.96e-4)" "unprognostic (5.60e-2)" "unprognostic (2.09e-2)" "unprognostic (2.45e-3)" "potential prognostic favorable (6.42e-6)" "unprognostic (2.80e-2)" "unprognostic (2.02e-1)" "potential prognostic unfavorable (1.44e-5)" "unprognostic (2.89e-1)" "unprognostic (6.19e-3)" "unprognostic (1.07e-2)" "unprognostic (2.14e-2)" "unprognostic (4.63e-2)" "unprognostic (1.68e-1)" "unprognostic (2.65e-2)" "unprognostic (1.99e-1)" "unprognostic (9.34e-2)" "unprognostic (6.99e-2)" "unprognostic (1.16e-1)" "unprognostic (4.76e-2)" "unprognostic (3.19e-3)" "unprognostic (5.25e-2)" "unprognostic (1.34e-1)" "unprognostic (5.59e-3)" "unprognostic (7.59e-2)" LAMTOR4 C7orf59 ENSG00000188186 "Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4" Q0VGL1 7 100148912-100155944 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 852.4;Hofbauer cells: 704.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 3379.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020998 Enhanced Supported "Golgi apparatus,Lysosomes" NA NA 9800 "Cluster 21: Neutrophils - Unknown function" "Cluster 2: Non-specific - Mixed function" "Cluster 27: Non-specific - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 35 Lysosomes "Golgi apparatus" "HPA020998: " "unprognostic (1.41e-1)" "unprognostic (1.15e-2)" "unprognostic (1.82e-2)" "unprognostic (1.35e-2)" "unprognostic (2.93e-1)" "unprognostic (1.00e-2)" "unprognostic (2.06e-1)" "unprognostic (3.53e-2)" "potential prognostic unfavorable (4.13e-5)" "unprognostic (2.60e-1)" "unprognostic (5.93e-2)" "unprognostic (1.22e-2)" "unprognostic (5.27e-3)" "unprognostic (6.66e-2)" "unprognostic (1.50e-1)" "unprognostic (1.90e-2)" "unprognostic (6.09e-3)" "unprognostic (2.52e-1)" "unprognostic (1.44e-1)" "unprognostic (2.93e-3)" "unprognostic (3.23e-1)" "unprognostic (1.15e-1)" "unprognostic (1.84e-1)" "unprognostic (5.37e-1)" "unprognostic (5.60e-2)" "unprognostic (6.76e-2)" "unprognostic (2.49e-1)" "unprognostic (9.55e-2)" "unprognostic (5.92e-3)" LAMTOR5 "HBXIP, MGC71071, XIP" ENSG00000134248 "Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5" O43504 1 110401249-110407942 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 666.3;Oocytes: 898.0;Parietal cells: 631.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006812 Approved Supported Cytosol NA NA 31000 "Cluster 22: Eosinophils - Transcription" "Cluster 72: Kidney - Transmembrane transport" "Cluster 21: Non-specific - Metabolism" "Cluster 37: Non-specific - mRNA processing" "Cluster 97: Non-specific - Cellular respiration" 66 Cytosol "HPA006812: " "unprognostic (1.71e-1)" "unprognostic (4.79e-2)" "unprognostic (7.42e-2)" "unprognostic (1.25e-2)" "unprognostic (1.54e-1)" "unprognostic (6.26e-2)" "unprognostic (3.50e-3)" "unprognostic (1.37e-3)" "unprognostic (1.81e-2)" "validated prognostic favorable (1.19e-5)" "validated prognostic favorable (2.07e-5)" "unprognostic (2.70e-2)" "potential prognostic unfavorable (1.06e-4)" "unprognostic (2.93e-2)" "unprognostic (5.30e-2)" "unprognostic (1.19e-1)" "unprognostic (5.88e-2)" "potential prognostic favorable (4.79e-4)" "unprognostic (3.29e-1)" "unprognostic (5.46e-2)" "unprognostic (8.46e-2)" "unprognostic (2.36e-1)" "unprognostic (2.06e-3)" "unprognostic (1.35e-1)" "unprognostic (3.60e-1)" "unprognostic (2.34e-1)" "unprognostic (1.47e-2)" "unprognostic (3.07e-3)" "unprognostic (2.46e-2)" LANCL1 "GPR69A, p40" ENSG00000115365 "LanC like glutathione S-transferase 1" O43813 2 210427131-210477652 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 161.6" "Cell type enhanced" "Detected in many" "Lactotrophs: 221.7;Oligodendrocytes: 662.4;Pituicytes/FSCs: 200.6" "Cell type enhanced" "Detected in all" "oligodendrocyte: 992.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034994 Enhanced Approved "Microtubules,Primary cilium,Basal body,Flagellar centriole,End piece" NA NA 22000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 80: Oligodendrocytes - Myelination" 23 "Microtubules, Primary cilium, Basal body, End piece" "Flagellar centriole" "HPA034994: " "unprognostic (6.61e-3)" "unprognostic (5.92e-2)" "unprognostic (2.68e-1)" "unprognostic (2.71e-1)" "unprognostic (2.10e-1)" "unprognostic (2.54e-1)" "unprognostic (1.84e-1)" "unprognostic (1.70e-2)" "unprognostic (9.42e-2)" "unprognostic (1.71e-3)" "potential prognostic favorable (1.22e-7)" "unprognostic (6.65e-3)" "unprognostic (1.43e-1)" "unprognostic (2.00e-2)" "unprognostic (2.85e-2)" "unprognostic (2.97e-2)" "unprognostic (2.81e-2)" "unprognostic (2.14e-1)" "unprognostic (3.03e-1)" "unprognostic (3.04e-2)" "unprognostic (5.30e-2)" "unprognostic (1.47e-2)" "unprognostic (3.04e-1)" "unprognostic (1.05e-1)" "unprognostic (9.06e-2)" "unprognostic (7.68e-3)" "unprognostic (8.55e-2)" "unprognostic (3.43e-1)" "unprognostic (1.29e-2)" "unprognostic (7.42e-2)" "unprognostic (1.40e-1)" LANCL2 "GPR69B, TASP" ENSG00000132434 "LanC like glutathione S-transferase 2" Q9NS86 7 55365337-55433737 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Glioblastoma Multiforme (TCGA): 85.3;Testicular Germ Cell Tumor (TCGA): 21.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019711, HPA029535" Uncertain Supported Nucleoplasm,Cytosol NA NA 16000 "Cluster 33: Non-specific - ATP binding" "Cluster 65: Brain - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 7 "Nucleoplasm, Cytosol" "HPA019711: , HPA029535: " "unprognostic (4.08e-2)" "unprognostic (7.39e-2)" "unprognostic (1.34e-1)" "unprognostic (9.20e-2)" "unprognostic (1.67e-1)" "unprognostic (1.33e-1)" "unprognostic (1.53e-1)" "unprognostic (2.05e-1)" "unprognostic (9.12e-2)" "unprognostic (4.29e-2)" "validated prognostic favorable (2.33e-5)" "validated prognostic favorable (1.84e-4)" "unprognostic (1.08e-3)" "unprognostic (1.30e-1)" "unprognostic (2.54e-1)" "unprognostic (1.88e-2)" "unprognostic (2.95e-2)" "unprognostic (7.90e-2)" "unprognostic (3.00e-1)" "unprognostic (8.11e-2)" "unprognostic (4.55e-2)" "potential prognostic favorable (1.12e-4)" "unprognostic (3.78e-1)" "unprognostic (1.06e-1)" "unprognostic (9.62e-2)" "unprognostic (5.86e-3)" "unprognostic (4.26e-1)" "potential prognostic unfavorable (5.55e-5)" "unprognostic (9.56e-3)" "unprognostic (1.72e-2)" "unprognostic (1.74e-2)" LANCL3 FLJ42925 ENSG00000147036 "LanC like family member 3" Q6ZV70 X 37571569-37684463 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in single" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 29.6;Pituicytes/FSCs: 178.2;Platelets: 217.5;Retinal ganglion cells: 42.5;Salivary ionocytes: 50.7" "Cell type enhanced" "Detected in many" "mammillary body: 52.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "basophil: 3.8" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.8" "Low cancer specificity" "Detected in some" "Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005470, HPA076575" Approved Approved Mitochondria NA NA "Cluster 41: Basophils - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 24: Non-specific - Unknown function" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" Mitochondria "HPA005470: , HPA076575: " "unprognostic (2.89e-3)" "unprognostic (5.96e-2)" LAP3 "LAP, LAPEP, PEPS" ENSG00000002549 "Leucine aminopeptidase 3" P28838 4 17577198-17607972 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 219.4;Hofbauer cells: 374.7;Late primary spermatocytes: 202.0" "Cell type enhanced" "Detected in all" "endothelial cell: 82.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029606, HPA029607" Enhanced Approved "Cytosol,Calyx,Mid piece,Principal piece" NA No 8000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 19: Astrocytes - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 15 Cytosol "Calyx, Mid piece, Principal piece" "HPA029606: , HPA029607: " "unprognostic (1.65e-2)" "unprognostic (1.80e-1)" "unprognostic (8.74e-3)" "unprognostic (1.30e-1)" "unprognostic (7.42e-2)" "unprognostic (1.10e-1)" "unprognostic (8.95e-2)" "unprognostic (2.01e-1)" "unprognostic (4.51e-1)" "unprognostic (6.17e-2)" "potential prognostic favorable (9.89e-5)" "unprognostic (2.87e-2)" "unprognostic (1.02e-2)" "unprognostic (4.15e-2)" "unprognostic (5.62e-2)" "unprognostic (1.06e-1)" "unprognostic (3.18e-2)" "unprognostic (2.82e-3)" "unprognostic (3.46e-1)" "unprognostic (1.06e-1)" "unprognostic (2.11e-1)" "unprognostic (1.68e-2)" "unprognostic (2.47e-1)" "unprognostic (2.58e-1)" "unprognostic (7.32e-2)" "unprognostic (4.02e-2)" "unprognostic (4.00e-2)" "unprognostic (1.04e-1)" "unprognostic (1.44e-2)" "unprognostic (4.42e-1)" "unprognostic (2.31e-1)" LAPTM4A "HUMORF13, KIAA0108, LAPTM4, MBNT, Mtrp" ENSG00000068697 "Lysosomal protein transmembrane 4 alpha" Q15012 2 20032650-20051628 "Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Decidual stromal cells: 1395.0;Early spermatids: 1524.3;Extravillous trophoblasts: 1546.3;Granulosa cells: 1249.7;Late spermatids: 1853.3;Mast cells: 1132.1" "Cell type enhanced" "Detected in all" "endothelial cell: 181.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Minor Salivary Gland - Macrophages, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031402, HPA031404, HPA068554" Approved Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 75: Ovary - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 108: Fibroblasts - ECM organization" 7 "Golgi apparatus, Vesicles" "Plasma membrane" "HPA031402: , HPA031404: , HPA068554: " "unprognostic (9.05e-2)" "unprognostic (2.95e-2)" "unprognostic (3.89e-2)" "unprognostic (1.77e-2)" "unprognostic (3.10e-1)" "unprognostic (7.05e-2)" "unprognostic (1.27e-1)" "unprognostic (5.32e-3)" "unprognostic (4.92e-3)" "unprognostic (5.24e-2)" "potential prognostic favorable (3.57e-6)" "unprognostic (9.35e-3)" "unprognostic (4.05e-2)" "unprognostic (5.23e-3)" "unprognostic (4.10e-2)" "unprognostic (1.19e-1)" "unprognostic (8.24e-2)" "unprognostic (1.06e-1)" "unprognostic (3.53e-1)" "unprognostic (6.22e-2)" "unprognostic (2.70e-2)" "unprognostic (4.61e-3)" "unprognostic (1.40e-1)" "unprognostic (1.28e-1)" "unprognostic (1.96e-1)" "unprognostic (7.12e-2)" "unprognostic (4.31e-1)" "unprognostic (1.57e-2)" "unprognostic (1.91e-1)" "unprognostic (1.96e-1)" "unprognostic (3.16e-1)" LAPTM4B LC27 ENSG00000104341 "Lysosomal protein transmembrane 4 beta" Q86VI4 8 97775057-97853013 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 352.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 472.0;Gastric progenitor cells: 335.8;Hematopoietic stem cells: 306.2;Rod photoreceptor cells: 641.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.3" "Group enriched" "Detected in many" 7 "granulocytes: 3.3;T-cells: 1.4" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020782, HPA068830" Uncertain Approved "Golgi apparatus" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 21: Non-specific - Metabolism" "Cluster 40: Non-specific - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" 21 "Golgi apparatus" "CAB020782: , HPA068830: " "unprognostic (6.85e-2)" "potential prognostic unfavorable (7.64e-4)" "unprognostic (9.37e-3)" "unprognostic (3.80e-2)" "unprognostic (7.75e-2)" "unprognostic (2.37e-1)" "unprognostic (2.60e-2)" "unprognostic (7.21e-2)" "potential prognostic unfavorable (7.67e-4)" "unprognostic (3.94e-2)" "unprognostic (2.14e-3)" "unprognostic (6.54e-3)" "unprognostic (4.90e-2)" "validated prognostic unfavorable (1.80e-5)" "validated prognostic unfavorable (2.37e-6)" "unprognostic (2.85e-1)" "unprognostic (1.19e-1)" "unprognostic (6.62e-2)" "unprognostic (4.77e-2)" "unprognostic (1.82e-2)" "unprognostic (4.53e-3)" "unprognostic (3.37e-2)" "unprognostic (1.82e-1)" "unprognostic (4.49e-2)" "unprognostic (1.20e-1)" "unprognostic (1.03e-1)" "unprognostic (3.36e-1)" "unprognostic (3.28e-2)" "unprognostic (2.98e-1)" "unprognostic (4.69e-2)" "unprognostic (3.88e-2)" LAPTM5 ENSG00000162511 "Lysosomal protein transmembrane 5" Q13571 1 30732469-30757774 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 1214.0;lymphoid tissue: 628.3" "Cell type enhanced" "Detected in many" "B-cells: 780.6;cDC: 473.8;Hofbauer cells: 935.6;Kupffer cells: 964.4;Macrophages: 775.5;Mast cells: 537.9;Monocyte progenitors: 535.5;monocytes: 1235.7;Neutrophil progenitors: 629.5;Neutrophils: 2085.6;T-cells: 301.3" "Group enriched" "Detected in some" 33 "central nervous system macrophage: 256.1;leukocyte: 227.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 503.4;lymphoma: 523.5" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Lung - Macrophages, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Spleen - Macrophages, Stomach - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051293 Approved Approved Cytosol NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 21 Cytosol "HPA051293: " "unprognostic (1.77e-2)" "unprognostic (1.84e-2)" "unprognostic (1.34e-1)" "unprognostic (2.88e-3)" "unprognostic (7.34e-2)" "unprognostic (2.42e-1)" "unprognostic (4.46e-2)" "unprognostic (2.45e-1)" "unprognostic (1.23e-1)" "unprognostic (2.98e-1)" "unprognostic (7.78e-2)" "unprognostic (3.76e-1)" "unprognostic (2.38e-1)" "unprognostic (1.25e-1)" "unprognostic (2.83e-1)" "unprognostic (7.82e-2)" "unprognostic (3.45e-3)" "unprognostic (4.43e-2)" "unprognostic (2.79e-2)" "unprognostic (1.13e-2)" "unprognostic (4.18e-1)" "unprognostic (5.79e-2)" "unprognostic (1.28e-1)" "unprognostic (1.33e-1)" "unprognostic (5.29e-2)" "unprognostic (5.68e-2)" "unprognostic (1.20e-3)" "unprognostic (1.08e-1)" "unprognostic (2.19e-2)" "unprognostic (2.01e-1)" "unprognostic (3.23e-1)" LARGE1 "KIAA0609, LARGE" ENSG00000133424 "LARGE xylosyl- and glucuronyltransferase 1" O95461 22 33162226-33922841 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Glycosyltransferase, Multifunctional enzyme, Transferase" "Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Lissencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 57.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 1421.2;Choroid plexus epithelial cells: 906.8;Podocytes: 2027.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.2" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 51: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" 1 "unprognostic (1.70e-3)" "unprognostic (2.37e-1)" "unprognostic (1.17e-1)" "unprognostic (5.29e-2)" "unprognostic (2.46e-1)" "unprognostic (2.72e-1)" "unprognostic (1.45e-3)" "unprognostic (2.18e-2)" "unprognostic (2.05e-2)" "unprognostic (1.25e-2)" "potential prognostic favorable (3.07e-4)" "unprognostic (1.89e-1)" "unprognostic (4.01e-2)" "unprognostic (4.17e-2)" "unprognostic (3.96e-1)" "unprognostic (7.25e-2)" "unprognostic (1.33e-1)" "unprognostic (5.47e-2)" "unprognostic (1.19e-1)" "unprognostic (3.64e-2)" "unprognostic (1.19e-1)" "unprognostic (9.44e-3)" "unprognostic (8.37e-2)" "unprognostic (1.63e-1)" "unprognostic (3.51e-2)" "unprognostic (1.68e-1)" "unprognostic (5.04e-2)" "unprognostic (1.23e-1)" "unprognostic (9.49e-2)" LARGE2 "FLJ35207, GYLTL1B, PP5656" ENSG00000165905 "LARGE xylosyl- and glucuronyltransferase 2" Q8N3Y3 11 45921621-45929096 "Predicted intracellular proteins" "Glycosyltransferase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 34.4" "Group enriched" "Detected in many" 4 "Breast lactating cells: 289.7;Cytotrophoblasts: 331.3;Migrating cytotrophoblasts: 95.2;Syncytiotrophoblasts: 139.2" "Cell type enriched" "Detected in some" 7 "choroid plexus epithelial cell: 28.6" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 13 "choroid plexus: 26.5" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.4;naive B-cell: 2.1" "Lineage enriched" "Detected in single" 4 "B-cells: 2.1" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2, Skin - Outer root sheath cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA056621 Approved "Intracellular and membrane" Enzyme NA NA "Cluster 34: B-cells - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 36: Choroid plexus - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 9 "HPA056621: " "unprognostic (8.37e-2)" "unprognostic (7.38e-2)" "unprognostic (4.64e-2)" "unprognostic (2.38e-1)" "potential prognostic favorable (2.94e-4)" "unprognostic (6.08e-3)" "unprognostic (6.35e-2)" "potential prognostic favorable (3.21e-7)" "unprognostic (1.22e-2)" "potential prognostic favorable (4.70e-7)" "unprognostic (8.59e-2)" "unprognostic (5.79e-2)" "unprognostic (3.68e-2)" "unprognostic (9.72e-3)" "unprognostic (3.50e-1)" "unprognostic (1.45e-1)" "unprognostic (1.17e-1)" "unprognostic (1.31e-1)" "unprognostic (5.71e-2)" "unprognostic (3.05e-1)" "unprognostic (2.00e-1)" "unprognostic (6.00e-3)" "unprognostic (1.68e-1)" "unprognostic (2.09e-2)" "unprognostic (1.47e-1)" "unprognostic (2.21e-1)" "unprognostic (3.95e-2)" LARP1 "KIAA0731, Lar1, LARP, Lhp1, MGC19556" ENSG00000155506 "La ribonucleoprotein 1, translational regulator" Q6PKG0 5 154682986-154817605 "Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis, Translation regulation" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015222, HPA051397, HPA054819" Approved Supported "Nucleoplasm,Endoplasmic reticulum,Cytosol" NA NA 24000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 1: Neurons - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 89: Adipocytes - Lipid metabolism" 60 "Nucleoplasm, Endoplasmic reticulum, Cytosol" "CAB015222: , HPA051397: , HPA054819: " "unprognostic (1.14e-2)" "unprognostic (1.05e-2)" "unprognostic (2.22e-1)" "unprognostic (1.09e-2)" "unprognostic (5.30e-2)" "unprognostic (1.77e-2)" "unprognostic (3.53e-2)" "unprognostic (6.80e-2)" "unprognostic (1.49e-2)" "unprognostic (6.45e-3)" "potential prognostic favorable (6.90e-4)" "unprognostic (1.51e-1)" "unprognostic (2.13e-1)" "unprognostic (4.84e-2)" "potential prognostic unfavorable (6.52e-4)" "validated prognostic unfavorable (2.62e-4)" "validated prognostic unfavorable (1.68e-4)" "unprognostic (1.12e-1)" "unprognostic (2.26e-1)" "unprognostic (2.46e-2)" "unprognostic (1.10e-1)" "unprognostic (1.83e-2)" "potential prognostic unfavorable (2.33e-4)" "unprognostic (4.21e-2)" "unprognostic (8.01e-2)" "unprognostic (1.05e-1)" "unprognostic (2.06e-1)" "unprognostic (2.12e-1)" "unprognostic (2.55e-1)" "unprognostic (2.04e-2)" "unprognostic (1.98e-1)" LARP1B "DKFZp434K245, DKFZp686E0316, FLJ10378, LARP2" ENSG00000138709 "La ribonucleoprotein 1B" Q659C4 4 128061286-128222931 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 612.9;Late primary spermatocytes: 570.4;Late spermatids: 744.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036280 Approved Approved Cytosol NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 21: Testis - Mixed function" "Cluster 34: Non-specific - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 55: Myocytes - Oxidative muscle function" 45 Cytosol "HPA036280: " "unprognostic (2.31e-1)" "unprognostic (2.76e-2)" "unprognostic (3.11e-1)" "unprognostic (3.20e-1)" "unprognostic (5.03e-2)" "unprognostic (2.38e-1)" "unprognostic (1.67e-1)" "unprognostic (2.48e-1)" "unprognostic (1.81e-1)" "unprognostic (3.20e-3)" "potential prognostic favorable (4.95e-7)" "unprognostic (1.03e-2)" "unprognostic (6.85e-2)" "unprognostic (2.51e-1)" "unprognostic (2.35e-2)" "unprognostic (1.85e-1)" "potential prognostic unfavorable (5.05e-4)" "unprognostic (2.01e-1)" "unprognostic (1.05e-2)" "unprognostic (2.51e-2)" "unprognostic (2.25e-1)" "unprognostic (1.37e-3)" "unprognostic (6.60e-2)" "unprognostic (7.59e-2)" "unprognostic (3.51e-2)" "unprognostic (3.29e-2)" "unprognostic (3.31e-1)" "unprognostic (1.10e-1)" "unprognostic (8.00e-2)" "unprognostic (2.73e-2)" "unprognostic (5.22e-2)" LARP4 PP13296 ENSG00000161813 "La ribonucleoprotein 4" Q71RC2 12 50392383-50480004 "Predicted intracellular proteins" "Protein biosynthesis" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Myonuclei: 348.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039306, HPA039673" Approved Enhanced "Nucleoli fibrillar center,Cytosol" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 76: Non-specific - Metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 38: Non-specific - Transcription" "Cluster 103: Non-specific - Basic cellular processes" 37 Cytosol "Nucleoli fibrillar center" "HPA039306: , HPA039673: " "unprognostic (1.22e-1)" "unprognostic (1.18e-2)" "unprognostic (7.27e-2)" "unprognostic (1.40e-2)" "unprognostic (1.03e-1)" "unprognostic (3.52e-3)" "unprognostic (3.29e-1)" "unprognostic (2.61e-2)" "unprognostic (2.59e-1)" "unprognostic (3.04e-3)" "potential prognostic favorable (8.82e-4)" "unprognostic (3.66e-1)" "unprognostic (1.49e-1)" "unprognostic (2.54e-1)" "unprognostic (3.82e-1)" "unprognostic (2.60e-2)" "unprognostic (2.32e-1)" "unprognostic (2.31e-1)" "unprognostic (3.10e-1)" "unprognostic (2.37e-1)" "unprognostic (1.30e-2)" "unprognostic (1.23e-3)" "unprognostic (1.99e-3)" "unprognostic (2.08e-1)" "unprognostic (4.82e-2)" "unprognostic (3.19e-1)" "unprognostic (7.69e-2)" "unprognostic (2.35e-1)" "unprognostic (4.26e-1)" "unprognostic (6.48e-2)" "unprognostic (1.41e-1)" LARP4B "KIAA0217, LARP5" ENSG00000107929 "La ribonucleoprotein 4B" Q92615 10 806933-931821 "Predicted intracellular proteins, Predicted membrane proteins" "Translation regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 652.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036566, HPA042738" Approved Enhanced Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 24: Neurons - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 68 Cytosol "HPA036566: , HPA042738: " "potential prognostic favorable (1.52e-4)" "unprognostic (1.19e-2)" "unprognostic (8.71e-2)" "unprognostic (8.50e-2)" "unprognostic (2.90e-1)" "unprognostic (1.36e-2)" "unprognostic (3.34e-2)" "potential prognostic favorable (4.59e-5)" "unprognostic (1.43e-2)" "unprognostic (9.13e-2)" "unprognostic (3.02e-3)" "unprognostic (2.15e-1)" "unprognostic (2.19e-1)" "potential prognostic unfavorable (3.46e-4)" "unprognostic (1.54e-3)" "unprognostic (5.93e-2)" "unprognostic (9.13e-2)" "unprognostic (1.95e-1)" "unprognostic (1.18e-1)" "unprognostic (6.05e-2)" "unprognostic (3.23e-2)" "unprognostic (4.81e-1)" "unprognostic (2.23e-2)" "unprognostic (1.63e-1)" "unprognostic (3.81e-2)" "unprognostic (4.09e-1)" "unprognostic (4.86e-2)" "unprognostic (1.10e-1)" "unprognostic (1.67e-1)" "unprognostic (3.76e-2)" "unprognostic (1.98e-1)" LARP6 "acheron, FLJ11196" ENSG00000166173 "La ribonucleoprotein 6, translational regulator" Q9BRS8 15 70829130-70854157 "Predicted intracellular proteins" "Translation regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 123.6" "Cell type enhanced" "Detected in many" "Early spermatids: 365.0;Epididymal efferent duct absorptive cells: 98.2;Epididymal efferent duct ciliated cells: 141.4;Epididymal principal cells: 231.1;Late primary spermatocytes: 481.3;Late spermatids: 328.2;Oligodendrocytes: 141.9" "Cell type enhanced" "Detected in all" "oligodendrocyte: 166.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020338, HPA049029" Approved Approved "Microtubules,Cytokinetic bridge" Yes No "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 4 Microtubules "Cytokinetic bridge" "HPA020338: , HPA049029: " "unprognostic (8.72e-2)" "potential prognostic favorable (7.89e-4)" "unprognostic (1.77e-1)" "unprognostic (3.82e-1)" "unprognostic (1.04e-1)" "unprognostic (4.13e-2)" "unprognostic (2.31e-2)" "unprognostic (1.51e-1)" "unprognostic (1.58e-2)" "unprognostic (9.94e-2)" "unprognostic (2.15e-2)" "unprognostic (4.95e-3)" "unprognostic (2.72e-1)" "unprognostic (9.88e-3)" "unprognostic (1.57e-2)" "unprognostic (5.21e-3)" "unprognostic (2.78e-1)" "unprognostic (2.56e-2)" "unprognostic (1.77e-2)" "unprognostic (2.75e-2)" "unprognostic (4.04e-1)" "unprognostic (3.89e-2)" "unprognostic (2.44e-3)" "unprognostic (3.57e-2)" "unprognostic (1.81e-1)" "unprognostic (6.47e-2)" "unprognostic (1.41e-1)" "unprognostic (3.51e-3)" "unprognostic (3.62e-2)" "unprognostic (2.44e-1)" "unprognostic (3.49e-2)" LARP7 "DKFZP564K112, HDCMA18P, PIP7S" ENSG00000174720 "La ribonucleoprotein 7, transcriptional regulator" Q4G0J3 4 112637077-112657696 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, mRNA processing, mRNA splicing, Spermatogenesis, Transcription, Transcription regulation" RNA-binding "Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026842, HPA027930" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 44: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 225 "Nucleoplasm, Cytosol" "HPA026842: , HPA027930: " "unprognostic (2.16e-1)" "unprognostic (7.26e-2)" "unprognostic (2.77e-1)" "unprognostic (5.07e-2)" "unprognostic (1.17e-1)" "unprognostic (4.87e-2)" "unprognostic (1.52e-1)" "unprognostic (2.65e-1)" "unprognostic (7.26e-2)" "unprognostic (4.41e-3)" "validated prognostic favorable (1.13e-5)" "validated prognostic favorable (6.01e-4)" "unprognostic (2.57e-1)" "unprognostic (1.99e-2)" "unprognostic (2.10e-2)" "unprognostic (9.11e-2)" "unprognostic (1.24e-2)" "unprognostic (1.47e-1)" "unprognostic (2.30e-2)" "unprognostic (1.19e-1)" "unprognostic (2.10e-3)" "unprognostic (2.37e-1)" "unprognostic (2.34e-2)" "unprognostic (1.72e-2)" "unprognostic (6.59e-3)" "unprognostic (2.80e-1)" "unprognostic (5.69e-2)" "unprognostic (2.43e-1)" "unprognostic (2.66e-1)" "unprognostic (3.40e-1)" "unprognostic (1.32e-1)" LARS1 "FLJ10595, FLJ21788, HSPC192, LARS, LEUS, RNTLS" ENSG00000133706 "Leucyl-tRNA synthetase 1" Q9P2J5 5 146110566-146182696 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036424, HPA040881" Supported Approved "Nuclear bodies,Cytosol" NA NA 78000 "Cluster 14: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 17: Non-specific - RNA processing" 49 "Nuclear bodies, Cytosol" "HPA036424: , HPA040881: " "unprognostic (6.61e-2)" "unprognostic (4.30e-3)" "unprognostic (2.28e-1)" "unprognostic (2.75e-1)" "unprognostic (1.42e-1)" "unprognostic (2.75e-1)" "unprognostic (1.37e-1)" "unprognostic (1.81e-1)" "potential prognostic unfavorable (9.75e-5)" "potential prognostic favorable (1.88e-4)" "unprognostic (9.53e-2)" "unprognostic (4.83e-1)" "potential prognostic unfavorable (3.06e-5)" "unprognostic (1.29e-2)" "unprognostic (1.42e-1)" "potential prognostic favorable (8.93e-4)" "unprognostic (1.38e-1)" "unprognostic (2.96e-2)" "unprognostic (2.75e-2)" "unprognostic (1.36e-1)" "unprognostic (1.75e-1)" "unprognostic (6.21e-2)" "unprognostic (1.30e-3)" "unprognostic (1.67e-1)" "unprognostic (4.44e-2)" "unprognostic (5.78e-2)" "unprognostic (7.80e-2)" "unprognostic (1.19e-2)" "unprognostic (1.59e-1)" LARS2 "KIAA0028, LEURS, MGC26121, mtLeuRS" ENSG00000011376 "Leucyl-tRNA synthetase 2, mitochondrial" Q15031 3 45388561-45554726 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Stomach - Mitotic cells (Stomach), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035950, HPA035951, HPA045450, HPA066085" Approved Approved Mitochondria NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 19: Astrocytes - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Transcription" 34 Mitochondria "HPA035950: , HPA035951: , HPA045450: , HPA066085: " "unprognostic (3.28e-1)" "unprognostic (1.50e-1)" "unprognostic (2.42e-1)" "unprognostic (1.59e-1)" "validated prognostic favorable (1.47e-4)" "validated prognostic favorable (3.07e-4)" "unprognostic (3.00e-1)" "unprognostic (2.99e-1)" "unprognostic (1.78e-1)" "unprognostic (1.21e-1)" "potential prognostic favorable (4.40e-6)" "unprognostic (7.07e-3)" "unprognostic (1.01e-2)" "unprognostic (7.71e-3)" "unprognostic (9.30e-3)" "unprognostic (1.72e-2)" "unprognostic (1.92e-3)" "unprognostic (1.52e-1)" "unprognostic (1.74e-1)" "unprognostic (1.72e-1)" "unprognostic (8.75e-2)" "unprognostic (1.96e-1)" "unprognostic (1.55e-1)" "unprognostic (1.44e-1)" "unprognostic (4.03e-3)" "unprognostic (7.79e-2)" "unprognostic (4.12e-2)" "unprognostic (2.37e-1)" "unprognostic (4.54e-2)" "unprognostic (2.50e-1)" "unprognostic (7.40e-2)" LAS1L "FLJ12525, Las1" ENSG00000001497 "LAS1 like ribosome biogenesis factor" Q9Y4W2 X 65438549-65534810 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "rRNA processing" Hydrolase "Disease variant, Intellectual disability, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 235.2;Sertoli cells: 111.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044431, HPA061463" Supported Approved "Nucleoplasm,Primary cilium transition zone,Centriolar satellite,Centrosome,Basal body,Cytosol" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 51 Nucleoplasm "Primary cilium transition zone, Centriolar satellite, Centrosome, Basal body, Cytosol" "HPA044431: , HPA061463: " "unprognostic (1.04e-1)" "unprognostic (8.13e-3)" "unprognostic (2.47e-1)" "unprognostic (2.64e-3)" "unprognostic (9.13e-2)" "unprognostic (6.41e-2)" "unprognostic (2.95e-1)" "potential prognostic favorable (9.08e-4)" "unprognostic (9.47e-3)" "unprognostic (2.12e-2)" "unprognostic (2.27e-3)" "unprognostic (8.36e-2)" "unprognostic (6.82e-2)" "unprognostic (2.64e-2)" "unprognostic (1.11e-3)" "unprognostic (6.10e-2)" "unprognostic (4.06e-3)" "unprognostic (3.29e-2)" "unprognostic (1.15e-1)" "unprognostic (8.57e-2)" "unprognostic (9.90e-2)" "unprognostic (3.53e-2)" "unprognostic (2.48e-1)" "unprognostic (4.37e-2)" "unprognostic (4.46e-1)" "unprognostic (5.31e-2)" "unprognostic (1.71e-1)" "unprognostic (7.63e-2)" "potential prognostic favorable (7.60e-4)" "unprognostic (3.72e-2)" "unprognostic (2.69e-2)" LASP1 "Lasp-1, MLN50" ENSG00000002834 "LIM and SH3 protein 1" Q14847 17 38869859-38921770 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Ion transport, Transport" Actin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 343.9;Foveolar cells: 290.5;Hepatic stellate cells: 296.9;Late spermatids: 1082.0;Neutrophils: 420.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012072, CAB022049" Enhanced Approved "Golgi apparatus,Plasma membrane,Focal adhesion sites,Cytosol" NA NA 14000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 77: Intestine - Digestion" "Cluster 38: Sub-cortical - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 35 "Plasma membrane, Cytosol" "Golgi apparatus, Focal adhesion sites" "CAB022049: , HPA012072: " "unprognostic (5.01e-2)" "unprognostic (2.56e-1)" "unprognostic (5.77e-2)" "potential prognostic unfavorable (1.82e-4)" "unprognostic (2.96e-1)" "unprognostic (2.19e-1)" "unprognostic (1.92e-1)" "unprognostic (3.46e-2)" "unprognostic (1.80e-1)" "unprognostic (6.51e-2)" "potential prognostic favorable (5.22e-5)" "unprognostic (5.25e-2)" "unprognostic (2.49e-1)" "potential prognostic unfavorable (9.95e-5)" "unprognostic (1.48e-2)" "potential prognostic unfavorable (3.14e-4)" "unprognostic (1.73e-2)" "unprognostic (1.47e-2)" "unprognostic (1.67e-1)" "unprognostic (7.29e-2)" "unprognostic (7.26e-2)" "unprognostic (1.73e-2)" "unprognostic (3.00e-2)" "unprognostic (1.18e-1)" "unprognostic (4.58e-2)" "unprognostic (2.75e-1)" "unprognostic (7.20e-2)" "unprognostic (1.05e-2)" "unprognostic (2.65e-1)" "unprognostic (1.70e-2)" "unprognostic (1.39e-1)" LAT LAT1 ENSG00000213658 "Linker for activation of T cells" O43561 16 28984826-28990784 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Adaptive immunity, Immunity, Mast cell degranulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 105.7" "Cell type enhanced" "Detected in some" "Astrocytes: 9.0;Bergmann glia: 5.0;Brain excitatory neurons: 5.8;Brain inhibitory neurons: 7.2;Choroid plexus epithelial cells: 4.7;Distal convoluted tubule cells: 6.8;Loop of henle epithelial cells: 7.2;Mast cells: 5.0;Megakaryocytes: 6.2;Microglia: 5.4;NK-cells: 5.8;Oligodendrocytes: 5.7;Other brain neurons: 4.6;Papillary tip epithelial cells: 4.7;Platelets: 9.8;Podocytes: 7.0;Proximal tubule cells: 11.4;Renal collecting duct intercalated cells: 4.7;Renal collecting duct principal cells: 6.7;Renal connecting tubule cells: 7.7;T-cells: 8.4" "Cell type enriched" "Detected in all" 6 "leukocyte: 75.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 20 "basophil: 308.6;gdT-cell: 303.5;MAIT T-cell: 212.3;memory CD4 T-cell: 295.3;memory CD8 T-cell: 306.9;naive CD4 T-cell: 276.3;naive CD8 T-cell: 267.4;NK-cell: 114.7;T-reg: 411.7" "Group enriched" "Detected in all" 172 "granulocytes: 308.6;NK-cells: 114.7;T-cells: 411.7" "Cancer enhanced" "Detected in all" "Leukemia: 87.4" "Adipose visceral - T-cells, Spleen - T-cells, Stomach - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002223, HPA011157, CAB012978, CAB079960" Enhanced Supported "Golgi apparatus,Plasma membrane" NA NA 93000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 80: Thymus - Adaptive immune response" "Cluster 15: Non-specific - Transcription" "Cluster 59: Leukemia - T-cell receptor" "Cluster 102: Non-specific - Mixed function" 29 "Plasma membrane" "Golgi apparatus" "CAB002223: , CAB012978: , CAB079960: , HPA011157: " "unprognostic (3.79e-1)" "unprognostic (4.51e-3)" "unprognostic (1.38e-2)" "potential prognostic favorable (9.44e-4)" "unprognostic (1.67e-2)" "unprognostic (1.77e-1)" "unprognostic (1.48e-1)" "potential prognostic favorable (6.26e-4)" "unprognostic (1.89e-2)" "potential prognostic unfavorable (1.29e-5)" "unprognostic (8.78e-2)" "unprognostic (6.20e-2)" "unprognostic (9.10e-2)" "unprognostic (3.13e-2)" "unprognostic (1.81e-2)" "unprognostic (5.39e-2)" "unprognostic (1.58e-1)" "unprognostic (1.39e-1)" "unprognostic (6.42e-2)" "potential prognostic favorable (4.17e-4)" "unprognostic (2.93e-2)" "potential prognostic unfavorable (1.30e-5)" "unprognostic (5.81e-2)" "unprognostic (1.66e-1)" "unprognostic (1.94e-2)" "unprognostic (4.66e-2)" "unprognostic (3.76e-2)" "unprognostic (5.16e-2)" "unprognostic (1.64e-1)" "unprognostic (2.47e-2)" LAT2 "HSPC046, LAB, NTAL, WBSCR15, WBSCR5, WSCR5" ENSG00000086730 "Linker for activation of T cells family member 2" Q9GZY6 7 74199652-74229834 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Adaptive immunity, Immunity, Mast cell degranulation" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 57.8;lymphoid tissue: 53.0" "Cell type enhanced" "Detected in many" "B-cells: 118.3;cDC: 132.4;Hofbauer cells: 106.7;Macrophages: 102.1;Mast cells: 199.4;Megakaryocyte progenitors: 76.9;Microglia: 142.1;Monocyte progenitors: 125.5;monocytes: 124.5;Neutrophil progenitors: 75.1;Neutrophils: 352.2;NK-cells: 148.0;Thymocytes: 95.7" "Cell type enriched" "Detected in all" 5 "central nervous system macrophage: 173.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 873.1" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Leukemia: 200.3;lymphoma: 102.9" "Adipose subcutaneous - Macrophages, Adrenal gland - Macrophages, Lung - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003462 Enhanced Supported "Plasma membrane" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 6: Leukemia - Signal transduction" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 1 "Plasma membrane" "HPA003462: " "unprognostic (1.81e-1)" "unprognostic (9.74e-2)" "unprognostic (3.69e-1)" "unprognostic (1.10e-3)" "unprognostic (1.19e-2)" "unprognostic (4.13e-1)" "unprognostic (4.48e-1)" "unprognostic (7.11e-2)" "unprognostic (1.36e-2)" "unprognostic (4.28e-1)" "unprognostic (3.78e-2)" "unprognostic (2.17e-1)" "unprognostic (2.04e-1)" "unprognostic (2.84e-3)" "unprognostic (2.53e-1)" "unprognostic (1.63e-2)" "unprognostic (4.78e-2)" "unprognostic (7.32e-2)" "unprognostic (6.52e-2)" "unprognostic (3.92e-2)" "unprognostic (3.82e-1)" "unprognostic (2.93e-2)" "unprognostic (3.48e-3)" "unprognostic (1.59e-1)" "unprognostic (4.33e-2)" "unprognostic (2.67e-2)" "unprognostic (1.00e-1)" "unprognostic (7.24e-2)" "unprognostic (1.37e-3)" "unprognostic (1.81e-1)" "unprognostic (1.26e-2)" LATS1 WARTS ENSG00000131023 "Large tumor suppressor kinase 1" O95835 6 149658153-149718105 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 255.2;Myonuclei: 218.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031804 Approved NA NA "Cluster 32: Basophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 102 "HPA031804: " "unprognostic (7.52e-2)" "potential prognostic unfavorable (2.51e-4)" "unprognostic (4.86e-2)" "unprognostic (2.36e-3)" "unprognostic (2.43e-1)" "unprognostic (3.07e-1)" "unprognostic (9.55e-2)" "unprognostic (4.36e-1)" "unprognostic (1.14e-1)" "unprognostic (1.74e-2)" "potential prognostic favorable (5.13e-4)" "unprognostic (1.16e-2)" "unprognostic (4.43e-2)" "unprognostic (1.63e-3)" "unprognostic (7.71e-2)" "unprognostic (5.53e-2)" "unprognostic (4.53e-2)" "unprognostic (1.20e-1)" "unprognostic (8.10e-2)" "potential prognostic unfavorable (6.77e-4)" "unprognostic (3.36e-2)" "unprognostic (2.48e-2)" "unprognostic (1.04e-2)" "unprognostic (4.03e-1)" "unprognostic (8.66e-3)" "unprognostic (5.37e-3)" "unprognostic (3.34e-1)" "unprognostic (1.24e-1)" "unprognostic (2.69e-1)" "unprognostic (8.02e-2)" "unprognostic (5.67e-2)" LATS2 ENSG00000150457 "Large tumor suppressor kinase 2" Q9NRM7 13 20973036-21061586 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 250.1;Neutrophils: 446.0" "Cell type enhanced" "Detected in many" "endothelial cell: 124.1;fibroblast: 123.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039191, HPA049037" Approved Approved "Centriolar satellite,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 25: Non-specific - Transcription" "Cluster 72: Neuronal - Signal transduction" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 72 "Centriolar satellite, Cytosol" "HPA039191: , HPA049037: " "potential prognostic favorable (9.37e-4)" "unprognostic (2.59e-1)" "unprognostic (1.02e-1)" "potential prognostic unfavorable (1.23e-5)" "unprognostic (3.08e-2)" "unprognostic (2.99e-2)" "unprognostic (9.01e-2)" "potential prognostic unfavorable (2.24e-6)" "unprognostic (3.24e-2)" "potential prognostic favorable (8.96e-4)" "potential prognostic favorable (4.53e-6)" "unprognostic (2.42e-3)" "unprognostic (7.98e-2)" "unprognostic (1.76e-1)" "unprognostic (7.41e-2)" "unprognostic (5.21e-3)" "unprognostic (2.93e-2)" "unprognostic (1.40e-2)" "unprognostic (2.99e-1)" "unprognostic (2.02e-3)" "unprognostic (2.81e-3)" "unprognostic (4.23e-2)" "unprognostic (9.93e-2)" "unprognostic (2.10e-1)" "unprognostic (1.30e-2)" "unprognostic (5.01e-2)" "unprognostic (2.50e-1)" "unprognostic (2.10e-2)" "unprognostic (2.68e-1)" "unprognostic (9.29e-2)" "unprognostic (9.29e-2)" LAX1 "FLJ20340, LAX" ENSG00000122188 "Lymphocyte transmembrane adaptor 1" Q8IWV1 1 203765177-203776372 "Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "lymphoid tissue: 19.8" "Cell type enhanced" "Detected in many" "B-cells: 21.4;Mast cells: 226.7;NK-cells: 51.2;Plasma cells: 103.0;T-cells: 60.7" "Cell type enriched" "Detected in single" 34 "leukocyte: 25.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 14 "B-cells: 7.5;NK-cells: 5.3;T-cells: 12.0" "Cancer enriched" "Detected in some" 6 "Myeloma: 40.5" "Adipose subcutaneous - Mast cells, Breast - Plasma cells, Colon - Mast cells, Minor Salivary Gland - Plasma cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA002461, HPA003887, CAB025358" Enhanced Enhanced "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 30: White matter - Myelination" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 58: Mast cells - Allergic inflammatory responses" 4 "Plasma membrane, Cytosol" "Golgi apparatus" "CAB025358: , HPA002461: , HPA003887: " "unprognostic (3.54e-2)" "unprognostic (9.46e-2)" "unprognostic (2.67e-1)" "unprognostic (5.91e-2)" "unprognostic (6.64e-2)" "potential prognostic favorable (1.45e-4)" "unprognostic (1.70e-1)" "unprognostic (3.83e-2)" "unprognostic (7.12e-3)" "unprognostic (1.31e-3)" "unprognostic (1.38e-2)" "unprognostic (2.17e-1)" "unprognostic (9.72e-2)" "unprognostic (2.64e-1)" "unprognostic (3.15e-2)" "unprognostic (1.11e-1)" "unprognostic (1.02e-1)" LAYN "FLJ30977, FLJ31092" ENSG00000204381 Layilin Q6UX15 11 111540280-111561745 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 75.2;Basal prostatic cells: 34.9;Epididymal basal cells: 31.6;Lymphatic endothelial cells: 131.5;Medullary thymic epithelial cells: 31.2;Oligodendrocytes: 38.3;Peritubular myoid cells: 52.4;Respiratory basal cells: 89.8;Respiratory deuterosomal cells: 45.6;Respiratory secretory cells: 84.2;Vascular endothelial cells: 36.0" "Cell type enhanced" "Detected in many" "endothelial cell: 43.0;oligodendrocyte: 41.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 21 "myeloid DC: 11.2;T-reg: 13.4" "Group enriched" "Detected in many" 124 "dendritic cells: 11.2;T-cells: 13.4" "Cancer enhanced" "Detected in many" "Brain cancer: 75.5" "Adrenal gland - Endothelial cells, Heart muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA040087 Approved Approved Cytosol NA NA 110000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 74: Non-specific - Signal transduction" "Cluster 11: White matter - Signal transduction" "Cluster 72: Neuronal - Signal transduction" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" Cytosol "HPA040087: " "unprognostic (1.79e-1)" "unprognostic (9.75e-2)" "unprognostic (3.70e-3)" "unprognostic (1.51e-1)" "unprognostic (1.40e-3)" "unprognostic (6.34e-2)" "unprognostic (7.02e-3)" "potential prognostic unfavorable (9.54e-5)" "unprognostic (2.92e-2)" "unprognostic (1.05e-1)" "unprognostic (2.21e-3)" "unprognostic (2.08e-2)" "unprognostic (6.08e-2)" "unprognostic (6.69e-3)" "unprognostic (1.10e-1)" "unprognostic (1.32e-1)" "unprognostic (4.66e-3)" "unprognostic (8.15e-2)" "unprognostic (9.62e-2)" "unprognostic (1.23e-3)" "unprognostic (7.33e-2)" "unprognostic (7.15e-2)" "unprognostic (1.81e-1)" "unprognostic (3.03e-1)" "unprognostic (4.10e-2)" "unprognostic (5.27e-3)" "unprognostic (1.75e-1)" "unprognostic (6.96e-3)" "unprognostic (9.51e-2)" "unprognostic (8.35e-3)" "unprognostic (5.13e-2)" LBH ENSG00000213626 "LBH regulator of WNT signaling pathway" Q53QV2 2 30231534-30323730 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 370.3;Cone photoreceptor cells: 544.4;Fallopian tube ciliated cells: 198.3;Late spermatids: 252.4;Vascular smooth muscle cells: 455.5" "Group enriched" "Detected in many" 4 "leukocyte: 140.6;pericyte: 210.7;vascular associated smooth muscle cell: 314.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "gdT-cell: 112.6;MAIT T-cell: 110.5;memory B-cell: 92.3;memory CD4 T-cell: 84.1;memory CD8 T-cell: 86.1;naive B-cell: 123.3;naive CD4 T-cell: 140.7;naive CD8 T-cell: 125.0;T-reg: 89.5" "Group enriched" "Detected in all" 7 "B-cells: 123.3;T-cells: 140.7" "Cancer enhanced" "Detected in many" "Bone cancer: 140.9" "Adipose visceral - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034669 Approved Approved Vesicles NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 103: Non-specific - Basic cellular processes" 1 Vesicles "HPA034669: " "unprognostic (1.18e-3)" "unprognostic (4.30e-2)" "unprognostic (3.62e-1)" "unprognostic (4.79e-2)" "unprognostic (1.26e-2)" "unprognostic (1.75e-1)" "unprognostic (2.02e-3)" "unprognostic (1.06e-1)" "unprognostic (8.64e-2)" "unprognostic (1.72e-1)" "validated prognostic favorable (2.31e-6)" "validated prognostic favorable (1.27e-4)" "unprognostic (1.35e-1)" "unprognostic (2.81e-1)" "unprognostic (6.54e-2)" "unprognostic (2.66e-2)" "unprognostic (1.40e-1)" "unprognostic (2.78e-2)" "unprognostic (2.60e-1)" "unprognostic (3.09e-2)" "unprognostic (1.57e-1)" "unprognostic (1.81e-1)" "unprognostic (2.20e-1)" "unprognostic (5.07e-2)" "unprognostic (2.44e-1)" "unprognostic (5.43e-2)" "unprognostic (1.43e-1)" "potential prognostic unfavorable (8.86e-4)" "unprognostic (5.38e-2)" "unprognostic (3.26e-2)" "unprognostic (5.62e-3)" LBHD1 "C11orf48, MGC2477" ENSG00000162194 "LBH domain containing 1" Q9BQE6 11 62662817-62672267 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 53.4" "Cell type enhanced" "Detected in many" "Adipocytes: 37.3;Cardiomyocytes: 159.0;Epicardial cells: 79.6;Erythrocyte progenitors: 26.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Uterine Corpus Endometrial Carcinoma (TCGA): 23.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "HPA012127, HPA023592" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 42: Retina - Visual perception" "Cluster 6: Non-specific - Immune response" "Cluster 24: Non-specific - Unknown function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" Nucleoplasm Cytosol "HPA012127: , HPA023592: " "unprognostic (2.54e-2)" "unprognostic (1.91e-2)" "unprognostic (1.07e-2)" "unprognostic (6.06e-3)" "unprognostic (6.76e-2)" "unprognostic (2.72e-2)" "potential prognostic favorable (3.25e-4)" "unprognostic (1.59e-1)" "unprognostic (1.77e-1)" "potential prognostic unfavorable (1.59e-4)" "unprognostic (5.47e-3)" "unprognostic (2.76e-2)" "potential prognostic unfavorable (2.37e-7)" "unprognostic (2.85e-1)" "unprognostic (6.52e-3)" "unprognostic (1.32e-1)" "unprognostic (4.58e-1)" "unprognostic (1.99e-1)" "unprognostic (1.99e-1)" "unprognostic (3.01e-1)" "unprognostic (2.41e-2)" "unprognostic (9.18e-2)" "unprognostic (1.54e-2)" "unprognostic (1.25e-1)" "unprognostic (1.45e-1)" "unprognostic (6.79e-2)" "unprognostic (2.20e-1)" "unprognostic (1.33e-2)" "unprognostic (1.95e-1)" LBHD2 ENSG00000283071 "LBH domain containing 2" A0A0U1RRK4 14 103084210-103090027 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.7;testis: 3.0" "Cell type enhanced" "Detected in some" "Decidual stromal cells: 5.5;Early spermatids: 1.5;Gastric chief cells: 2.2;Late primary spermatocytes: 1.7;Late spermatids: 8.5;Mesothelial cells: 1.3;Oocytes: 4.6;Other brain neurons: 3.1;Sertoli cells: 2.3;Undifferentiated spermatogonia: 4.2" "Group enriched" "Detected in some" 4 "hippocampal CA4: 6.9;lower rhombic lip: 5.5;splatter: 2.0;thalamic excitatory: 2.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "hypothalamus: 22.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Adipocytes (Breast)" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 24: Neurons - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 98: Neurons - Neurotransmission & signaling" "unprognostic (4.18e-3)" "unprognostic (9.22e-2)" "unprognostic (4.45e-2)" "unprognostic (2.48e-2)" "unprognostic (6.29e-2)" "unprognostic (1.13e-1)" "unprognostic (1.51e-2)" "unprognostic (1.41e-1)" LBP BPIFD2 ENSG00000129988 "Lipopolysaccharide binding protein" P18428 20 38346482-38377013 "Plasma proteins, Predicted secreted proteins, Transporters" "Immunity, Innate immunity, Lipid transport, Transport" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 24 "liver: 1320.7" "Cell type enriched" "Detected in some" 19 "Hepatocytes: 514.3" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 11 "Liver Hepatocellular Carcinoma (TCGA): 480.0" "Region enhanced" "Detected in single" "medulla oblongata: 2.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "Brain cancer: 6.7;breast cancer: 2.7;liver cancer: 2.3;lymphoma: 1.8;thyroid cancer: 2.9" "Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Thyroid gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001508, CAB025905" Approved "Secreted to blood" Transport NA NA 25000000000 4000000000 "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 39: Astrocytes - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 2 "CAB025905: , HPA001508: " "unprognostic (1.61e-2)" "unprognostic (9.91e-2)" "unprognostic (3.87e-3)" "unprognostic (4.90e-2)" "unprognostic (1.93e-1)" "unprognostic (1.00e-2)" "unprognostic (1.76e-1)" "unprognostic (5.18e-2)" "validated prognostic unfavorable (1.81e-6)" "validated prognostic unfavorable (2.47e-5)" "potential prognostic unfavorable (1.52e-4)" "unprognostic (1.47e-2)" "unprognostic (1.32e-1)" "unprognostic (7.77e-3)" "unprognostic (5.45e-3)" "unprognostic (1.73e-1)" "unprognostic (1.02e-1)" "unprognostic (1.16e-1)" "unprognostic (8.65e-2)" "unprognostic (1.07e-3)" "unprognostic (8.82e-2)" "unprognostic (2.03e-1)" LBR "DHCR14B, TDRD18" ENSG00000143815 "Lamin B receptor" Q14739 1 225401502-225428925 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "DNA-binding, Oxidoreductase, Receptor" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Erythrocyte progenitors: 337.4;Monocyte progenitors: 357.3;Neutrophil progenitors: 749.5;Neutrophils: 852.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Heart muscle - Endothelial cells, Prostate - Smooth muscle cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049840, HPA062236" Enhanced Supported "Nuclear membrane,Nucleoli fibrillar center" NA Yes "Cluster 35: Neutrophils - Protein binding" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 83 "Nuclear membrane" "Nucleoli fibrillar center" "HPA049840: , HPA062236: " "unprognostic (6.34e-2)" "unprognostic (2.43e-1)" "unprognostic (1.58e-1)" "unprognostic (3.31e-2)" "unprognostic (2.23e-2)" "unprognostic (1.29e-2)" "unprognostic (1.14e-1)" "unprognostic (1.01e-2)" "unprognostic (2.01e-1)" "unprognostic (1.68e-1)" "potential prognostic favorable (4.90e-4)" "unprognostic (1.07e-1)" "unprognostic (1.16e-1)" "potential prognostic unfavorable (3.28e-4)" "unprognostic (5.59e-3)" "unprognostic (1.90e-3)" "unprognostic (2.02e-3)" "unprognostic (6.44e-2)" "unprognostic (6.67e-2)" "unprognostic (2.62e-1)" "unprognostic (4.27e-1)" "unprognostic (5.22e-2)" "unprognostic (4.39e-1)" "unprognostic (1.64e-1)" "unprognostic (8.15e-3)" "unprognostic (1.04e-1)" "unprognostic (5.29e-2)" "unprognostic (2.43e-1)" "unprognostic (3.31e-1)" "unprognostic (8.68e-3)" "unprognostic (1.20e-1)" LBX1 "HPX6, LBX1H" ENSG00000138136 "Ladybird homeobox 1" P52954 10 101226994-101229463 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Myogenesis, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "skeletal muscle: 23.7" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 10 "cerebellar inhibitory: 13.8" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "cerebellum: 4.4;medulla oblongata: 8.1;pons: 6.0;spinal cord: 10.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 5.0" "Group enriched" "Detected in some" 24 "cerebellum: 1.6;pons and medulla: 3.0" "Group enriched" "Detected in some" 23 "cerebellum: 1.6;medulla oblongata: 2.6;spinal cord: 2.7" "HPA002016, HPA002086, CAB079927" Uncertain Approved "Nucleoplasm,Nucleoli,Nuclear bodies,Cytosol" NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 43: Hindbrain - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 20 Nucleoplasm "Nucleoli, Nuclear bodies, Cytosol" "CAB079927: , HPA002016: , HPA002086: " LBX2 ENSG00000179528 "Ladybird homeobox 2" Q6XYB7 2 74497517-74503316 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 5.0;liver: 9.1;stomach 1: 3.0" "Cell type enhanced" "Detected in many" "Enterocytes: 5.6;Epididymal efferent duct absorptive cells: 5.4;Gastric chief cells: 6.6;Gastric progenitor cells: 7.7;Hepatocytes: 5.8;Hofbauer cells: 6.9;Megakaryocytes: 12.4" "Cell type enhanced" "Detected in some" "endothelial cell: 1.3;fibroblast: 1.7;pericyte: 2.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 1.7" HPA044257 Uncertain Approved Nucleoplasm,Midbody Yes No "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 6: Non-specific - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" Nucleoplasm Midbody "HPA044257: " "unprognostic (2.66e-2)" "unprognostic (1.21e-1)" "unprognostic (2.10e-1)" "unprognostic (1.38e-1)" "unprognostic (1.90e-3)" "unprognostic (4.69e-2)" "unprognostic (9.14e-2)" "unprognostic (2.89e-1)" "unprognostic (3.42e-1)" "unprognostic (3.20e-2)" "unprognostic (2.01e-1)" "unprognostic (3.47e-2)" "unprognostic (5.73e-2)" "unprognostic (3.56e-1)" "unprognostic (1.46e-1)" "unprognostic (8.19e-2)" "unprognostic (2.35e-2)" "unprognostic (3.09e-1)" "unprognostic (1.19e-2)" "unprognostic (4.47e-1)" "unprognostic (1.30e-1)" "unprognostic (5.68e-1)" "unprognostic (5.03e-2)" "unprognostic (7.85e-2)" "unprognostic (8.74e-2)" "unprognostic (1.71e-2)" LCA5 C6orf152 ENSG00000135338 "Lebercilin LCA5" Q86VQ0 6 79484991-79537458 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant, Leber congenital amaurosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 251.6;Endometrial ciliated cells: 114.3;Ependymal cells: 248.5;Fallopian tube ciliated cells: 236.2;Respiratory ciliated cells: 211.8" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 250.0;ependymal cell: 279.8" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 9.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Prostate - Fibroblasts, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029053, HPA029054, HPA029055" Supported Supported "Golgi apparatus,Primary cilium tip,Centriolar satellite,Cytosol" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 47: Leukemia - Hemostasis" "Cluster 34: Ciliated cells - Cilia assembly & function" 31 "Primary cilium tip, Centriolar satellite" "Golgi apparatus, Cytosol" "HPA029053: , HPA029054: , HPA029055: " "unprognostic (1.15e-1)" "unprognostic (5.44e-2)" "unprognostic (1.02e-1)" "unprognostic (1.03e-2)" "potential prognostic unfavorable (2.75e-4)" "unprognostic (1.58e-1)" "unprognostic (6.09e-2)" "unprognostic (1.69e-1)" "validated prognostic favorable (5.04e-4)" "validated prognostic favorable (1.71e-4)" "unprognostic (2.75e-1)" "unprognostic (1.32e-2)" "unprognostic (8.76e-2)" "unprognostic (4.00e-1)" "unprognostic (1.28e-1)" "unprognostic (1.22e-1)" "potential prognostic unfavorable (3.66e-4)" "unprognostic (2.69e-1)" "unprognostic (2.94e-3)" "unprognostic (1.52e-1)" "unprognostic (2.29e-2)" "unprognostic (2.98e-2)" "unprognostic (2.03e-1)" "unprognostic (1.51e-1)" "unprognostic (6.20e-2)" LCA5L "C21orf13, MGC33295" ENSG00000157578 "Lebercilin LCA5 like" O95447 21 39405728-39445805 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "testis: 103.2" "Group enriched" "Detected in many" 8 "Early spermatids: 1231.7;Late primary spermatocytes: 1581.2;Late spermatids: 684.6" "Cell type enriched" "Detected in all" 4 "ependymal cell: 145.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA032010 Enhanced Approved "Nucleoplasm,Nuclear speckles,Cytosol,Flagellar centriole,Mid piece,Principal piece,End piece" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 17: Choroid plexus - Cilium" "Cluster 27: Breast cancer - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 14 "Nucleoplasm, Nuclear speckles, Flagellar centriole, Mid piece" "Cytosol, Principal piece, End piece" "HPA032010: " "unprognostic (3.76e-1)" "unprognostic (8.58e-2)" "unprognostic (3.32e-1)" "unprognostic (1.05e-2)" "unprognostic (7.79e-3)" "unprognostic (1.99e-1)" "unprognostic (1.07e-1)" "unprognostic (9.41e-2)" "unprognostic (4.26e-3)" "unprognostic (8.33e-2)" "unprognostic (1.24e-1)" "unprognostic (6.19e-2)" "unprognostic (1.37e-1)" "unprognostic (5.44e-3)" "unprognostic (1.88e-1)" "unprognostic (2.38e-1)" "unprognostic (1.47e-1)" "unprognostic (1.26e-1)" "unprognostic (9.58e-2)" LCAT ENSG00000213398 "Lecithin-cholesterol acyltransferase" P04180 16 67939750-67944131 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Acyltransferase, Hydrolase, Transferase" "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "liver: 275.5" "Group enriched" "Detected in many" 4 "Bergmann glia: 306.4;Hepatocytes: 241.4" "Cell type enriched" "Detected in many" 5 "Bergmann glia: 364.4" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 56.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 1.9" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044767 Approved Nucleoplasm "Secreted to blood" Enzyme NA NA 6470000000 1100000000 "Cluster 22: Eosinophils - Transcription" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 25: Non-specific - Transcription" "Cluster 34: Testis cancer - Unknown function" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 5 Nucleoplasm "HPA044767: " "unprognostic (1.77e-2)" "unprognostic (3.55e-2)" "unprognostic (3.43e-2)" "unprognostic (3.93e-1)" "unprognostic (3.02e-2)" "unprognostic (1.32e-1)" "unprognostic (4.68e-3)" "unprognostic (6.15e-3)" "unprognostic (1.62e-1)" "unprognostic (2.94e-2)" "potential prognostic unfavorable (7.62e-4)" "unprognostic (5.33e-2)" "unprognostic (5.08e-2)" "validated prognostic favorable (1.68e-7)" "validated prognostic favorable (1.05e-4)" "unprognostic (8.39e-2)" "unprognostic (9.04e-2)" "unprognostic (1.43e-1)" "unprognostic (2.81e-1)" "unprognostic (2.14e-1)" "unprognostic (3.47e-2)" "unprognostic (5.30e-2)" "unprognostic (1.71e-2)" "unprognostic (2.18e-1)" "unprognostic (5.46e-2)" "unprognostic (2.54e-2)" "potential prognostic unfavorable (1.38e-4)" "unprognostic (2.50e-2)" "unprognostic (2.67e-1)" "unprognostic (2.41e-1)" "unprognostic (7.66e-3)" LCE1A LEP1 ENSG00000186844 "Late cornified envelope 1A" Q5T7P2 1 152827473-152828097 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "skin 1: 379.3" "Cell type enriched" "Detected in single" 8 "Late spermatids: 1.1" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Skin Cutaneous Melanoma (TCGA): 21.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Keratinocyte (granular)" NA NA "Cluster 37: Skin - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 82: Dendritic cells - Antigen presentation" 59 "unprognostic (5.29e-2)" "unprognostic (6.17e-2)" LCE1B "LEP2, SPRL2A" ENSG00000196734 "Late cornified envelope 1B" Q5T7P3 1 152811971-152813108 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "skin 1: 167.7" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 10 "Skin Cutaneous Melanoma (TCGA): 10.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Keratinocyte (granular)" NA NA "Cluster 37: Skin - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 87 "unprognostic (1.60e-2)" "unprognostic (5.17e-2)" LCE1C LEP3 ENSG00000197084 "Late cornified envelope 1C" Q5T751 1 152804832-152806651 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "skin 1: 534.9" "Group enriched" "Detected in some" 4 "Basal keratinocytes: 11.2;Esophageal basal cells: 6.4" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Skin Cutaneous Melanoma (TCGA): 41.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 4.3;head and neck cancer: 2.3" "Skin - Keratinocyte (granular)" NA NA "Cluster 37: Skin - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 26: Keratinocytes - Keratinization" 56 "unprognostic (2.30e-2)" "unprognostic (6.62e-2)" "unprognostic (2.05e-1)" "unprognostic (3.96e-1)" "unprognostic (5.79e-2)" LCE1D LEP4 ENSG00000172155 "Late cornified envelope 1D" Q5T752 1 152796721-152798181 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 108 "skin 1: 87.7" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "Skin Cutaneous Melanoma (TCGA): 5.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Keratinocyte (granular)" NA NA "Cluster 37: Skin - Keratinization" "Cluster 61: BICR 18 - Protein kinases" 47 "unprognostic (4.63e-2)" LCE1E LEP5 ENSG00000186226 "Late cornified envelope 1E" Q5T753 1 152786214-152788426 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 55 "skin 1: 57.8" "Cell type enhanced" "Detected in single" "Urothelial cells: 1.7" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Skin Cutaneous Melanoma (TCGA): 3.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "cervical cancer: 1.9" "Skin - Keratinocyte (granular)" NA NA "Cluster 37: Skin - Keratinization" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 69: Urothelial cells - Basic cellular functions" 53 "unprognostic (2.43e-1)" LCE1F LEP6 ENSG00000240386 "Late cornified envelope 1F" Q5T754 1 152775140-152777024 "Essential proteins, Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "skin 1: 154.6" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Head and Neck Squamous Cell Carcinoma (TCGA): 12.0;Skin Cutaneous Melanoma (TCGA): 21.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "cervical cancer: 1.8;head and neck cancer: 3.5;thyroid cancer: 1.3" "Skin - Keratinocyte (granular)" NA NA "Cluster 37: Skin - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" 62 "unprognostic (1.14e-1)" "unprognostic (2.52e-2)" "unprognostic (4.82e-2)" LCE2A LEP9 ENSG00000187173 "Late cornified envelope 2A" Q5TA79 1 152698345-152699442 "Essential proteins, Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "skin 1: 111.6" "Cell type enriched" "Detected in single" 20 "Melanocytes: 4.3" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "Skin Cutaneous Melanoma (TCGA): 23.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 17 "thyroid cancer: 20.7" "Skin - Keratinocyte (granular)" NA NA "Cluster 37: Skin - Keratinization" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 61: Schwann cells & Melanocytes - Mixed function" 46 "unprognostic (2.49e-2)" "unprognostic (3.87e-2)" LCE2B "LEP10, SPRL1B, XP5" ENSG00000159455 "Late cornified envelope 2B" O14633 1 152686123-152687397 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "skin 1: 716.6" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Skin Cutaneous Melanoma (TCGA): 26.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 14 "head and neck cancer: 1.5" "Skin - Keratinocyte (granular)" NA NA "Cluster 37: Skin - Keratinization" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 103: Non-specific - Basic cellular processes" 56 "unprognostic (4.79e-2)" "unprognostic (5.35e-2)" LCE2C LEP11 ENSG00000187180 "Late cornified envelope 2C" Q5TA81 1 152675279-152676569 "Essential proteins, Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "skin 1: 313.4" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Skin Cutaneous Melanoma (TCGA): 23.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Keratinocyte (granular)" NA NA "Cluster 37: Skin - Keratinization" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 72 "unprognostic (3.97e-2)" "unprognostic (3.04e-2)" LCE2D "LEP12, SPRL1A" ENSG00000187223 "Late cornified envelope 2D" Q5TA82 1 152663380-152664659 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 22 "skin 1: 150.2" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 44 "Head and Neck Squamous Cell Carcinoma (TCGA): 2.4;Skin Cutaneous Melanoma (TCGA): 9.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Skin - Keratinocyte (granular)" NA NA "Cluster 37: Skin - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" 53 "unprognostic (5.18e-2)" "unprognostic (3.04e-2)" LCE3A LEP13 ENSG00000185962 "Late cornified envelope 3A" Q5TA76 1 152622834-152623103 "Essential proteins, Predicted intracellular proteins" Keratinization Antimicrobial "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "lymphoid tissue: 100.5" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 1.1;Early primary spermatocytes: 2.7;Early spermatids: 3.5;Esophageal apical cells: 1.3;Late spermatids: 2.6;Undifferentiated spermatogonia: 1.0" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Head and Neck Squamous Cell Carcinoma (TCGA): 80.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "thyroid cancer: 1.3" NA NA "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 56 "unprognostic (1.69e-2)" "unprognostic (5.03e-2)" "unprognostic (2.02e-1)" "unprognostic (1.26e-1)" LCE3B LEP14 ENSG00000187238 "Late cornified envelope 3B" Q5TA77 1 152613811-152614098 "Predicted intracellular proteins" Keratinization Antimicrobial "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 30 "lymphoid tissue: 2.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 34: Lymphoid tissue - Adaptive immune response" 34 LCE3C "LEP15, SPRL3A" ENSG00000244057 "Late cornified envelope 3C" Q5T5A8 1 152600234-152601086 "Predicted intracellular proteins" Keratinization Antimicrobial "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "lymphoid tissue: 22.6" "Cell type enhanced" "Detected in single" "Esophageal apical cells: 2.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 32 "Head and Neck Squamous Cell Carcinoma (TCGA): 8.0;Skin Cutaneous Melanoma (TCGA): 2.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 13 "head and neck cancer: 1.9" NA NA "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 84: Apical squamous epithelium - Cornification" 47 "unprognostic (5.32e-3)" LCE3D "LEP16, SPRL6A, SPRL6B" ENSG00000163202 "Late cornified envelope 3D" Q9BYE3 1 152579381-152580516 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 238.1;lymphoid tissue: 79.4;skin 1: 80.0;vagina: 199.4" "Cell type enriched" "Detected in some" 42 "Esophageal apical cells: 1129.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "Head and Neck Squamous Cell Carcinoma (TCGA): 257.3;Skin Cutaneous Melanoma (TCGA): 98.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Esophageal cancer: 4.1;head and neck cancer: 14.2" NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 45 "unprognostic (4.03e-2)" "unprognostic (5.58e-1)" "unprognostic (7.70e-2)" "unprognostic (1.12e-1)" "unprognostic (2.65e-1)" "unprognostic (1.32e-1)" LCE3E LEP17 ENSG00000185966 "Late cornified envelope 3E" Q5T5B0 1 152565654-152566780 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 54.8;lymphoid tissue: 18.1;skin 1: 19.0;vagina: 43.4" "Cell type enriched" "Detected in some" 41 "Esophageal apical cells: 267.9" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "Head and Neck Squamous Cell Carcinoma (TCGA): 81.4;Skin Cutaneous Melanoma (TCGA): 33.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "head and neck cancer: 7.0" NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 47 "unprognostic (2.64e-3)" "unprognostic (2.35e-1)" "unprognostic (1.47e-1)" "unprognostic (3.28e-2)" "unprognostic (2.10e-1)" "unprognostic (9.34e-2)" LCE4A "LEP8, SPRL4A" ENSG00000187170 "Late cornified envelope 4A" Q5TA78 1 152708160-152709434 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "skin 1: 4.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Keratinocyte (granular)" NA NA "Cluster 37: Skin - Keratinization" "Cluster 64: Connective tissue cells - ECM organization" 65 LCE5A "LEP18, SPRL5A" ENSG00000186207 "Late cornified envelope 5A" Q5TCM9 1 152510803-152512177 "Essential proteins, Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skin 1: 83.2" "Cell type enhanced" "Detected in some" "Esophageal apical cells: 4.0;Late primary spermatocytes: 1.0;Melanocytes: 2.0;Neutrophil progenitors: 1.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Skin Cutaneous Melanoma (TCGA): 1.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Keratinocyte (granular)" NA NA "Cluster 37: Skin - Keratinization" "Cluster 15: Kidney cancer - Membrane components" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 54 "unprognostic (2.33e-1)" LCE6A C1orf44 ENSG00000235942 "Late cornified envelope 6A" A0A183 1 152842856-152843983 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "skin 1: 232.3" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Skin Cutaneous Melanoma (TCGA): 9.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" HPA046376 Enhanced NA NA "Cluster 37: Skin - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "HPA046376: " "unprognostic (6.49e-2)" "unprognostic (5.18e-2)" LCE7A ENSG00000285946 "Late cornified envelope 7A" P0DV60 1 152859996-152861252 "Predicted intracellular proteins" Keratinization "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Tissue enriched" "Detected in single" 6 "skin 1: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Skin - Inner root sheath cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 37: Skin - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" LCK ENSG00000182866 "LCK proto-oncogene, Src family tyrosine kinase" P06239 1 32251244-32286165 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 17 "lymphoid tissue: 325.6" "Cell type enhanced" "Detected in many" "B-cells: 24.4;Innate lymphoid cells: 53.6;NK-cells: 172.2;T-cells: 256.2;Thymocytes: 52.5" "Cell type enriched" "Detected in some" 56 "leukocyte: 205.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Group enriched" "Detected in all" 12 "gdT-cell: 1075.1;MAIT T-cell: 1006.3;memory CD4 T-cell: 1091.0;memory CD8 T-cell: 1162.8;naive CD4 T-cell: 1226.0;naive CD8 T-cell: 1132.2;NK-cell: 627.6;T-reg: 1617.2" "Group enriched" "Detected in all" 12 "NK-cells: 627.6;T-cells: 1617.2" "Cancer enhanced" "Detected in many" "Leukemia: 92.1;lymphoma: 66.3" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Minor Salivary Gland - T-cells, Pancreas - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Skin - T-cells, Spleen - T-cells, Stomach - T-cells, Thyroid gland - T-cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in single" "HPA003494, CAB003816" Enhanced Approved "Golgi apparatus" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 80: Thymus - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" 85 "Golgi apparatus" "CAB003816: , HPA003494: " "potential prognostic favorable (4.17e-5)" "unprognostic (2.56e-3)" "unprognostic (2.13e-2)" "unprognostic (3.24e-2)" "unprognostic (3.87e-1)" "unprognostic (4.37e-2)" "unprognostic (1.49e-3)" "unprognostic (1.15e-1)" "potential prognostic favorable (4.77e-4)" "unprognostic (2.74e-1)" "unprognostic (1.30e-1)" "unprognostic (7.52e-2)" "unprognostic (7.50e-3)" "unprognostic (1.19e-2)" "unprognostic (6.58e-3)" "unprognostic (7.97e-3)" "unprognostic (2.33e-1)" "unprognostic (4.02e-1)" "unprognostic (1.46e-1)" "unprognostic (7.94e-3)" "unprognostic (5.23e-2)" "unprognostic (5.26e-2)" "unprognostic (2.33e-1)" "unprognostic (2.67e-1)" "unprognostic (1.50e-1)" "unprognostic (1.28e-2)" "potential prognostic favorable (4.21e-5)" "unprognostic (1.46e-1)" "unprognostic (2.15e-2)" "unprognostic (9.15e-2)" "unprognostic (5.02e-2)" LCLAT1 "AGPAT8, ALCAT1, FLJ37965, LPLAT6, LYCAT" ENSG00000172954 "Lysocardiolipin acyltransferase 1" Q6UWP7 2 30447226-30644225 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Developmental protein, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 322.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skin - Mitotic cells (Skin), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031880, HPA049217" Uncertain Supported "Endoplasmic reticulum,Cytosol" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 35: Non-specific - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 32: Non-specific - Cell proliferation" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 10 "Endoplasmic reticulum" Cytosol "HPA031880: , HPA049217: " "unprognostic (3.41e-1)" "unprognostic (1.05e-2)" "unprognostic (2.23e-2)" "unprognostic (1.61e-2)" "unprognostic (8.86e-2)" "unprognostic (1.65e-1)" "unprognostic (2.06e-1)" "unprognostic (7.19e-3)" "unprognostic (3.07e-3)" "unprognostic (5.04e-3)" "potential prognostic favorable (3.22e-5)" "unprognostic (1.00e-1)" "unprognostic (2.97e-1)" "validated prognostic unfavorable (2.12e-4)" "validated prognostic unfavorable (7.48e-5)" "unprognostic (1.49e-2)" "unprognostic (1.91e-2)" "unprognostic (5.52e-3)" "unprognostic (1.20e-2)" "unprognostic (2.08e-1)" "unprognostic (3.31e-1)" "unprognostic (2.33e-1)" "unprognostic (1.45e-2)" "unprognostic (3.07e-2)" "unprognostic (6.88e-2)" "unprognostic (5.54e-2)" "unprognostic (2.55e-1)" "unprognostic (1.10e-1)" "unprognostic (1.80e-1)" "unprognostic (6.46e-3)" "unprognostic (1.93e-1)" LCMT1 "CGI-68, PPMT1" ENSG00000205629 "Leucine carboxyl methyltransferase 1" Q9UIC8 16 25111731-25178231 "Enzymes, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 247.6;Oocytes: 460.5;Syncytiotrophoblasts: 205.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Liver - Vascular endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041559, HPA043530" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 3 "Nucleoplasm, Cytosol" "HPA041559: , HPA043530: " "unprognostic (2.54e-1)" "unprognostic (3.77e-3)" "unprognostic (1.76e-1)" "unprognostic (8.34e-3)" "unprognostic (1.88e-1)" "unprognostic (2.92e-1)" "unprognostic (1.16e-1)" "unprognostic (1.61e-1)" "unprognostic (1.64e-1)" "unprognostic (7.35e-2)" "potential prognostic favorable (3.60e-4)" "unprognostic (2.12e-1)" "unprognostic (2.96e-2)" "unprognostic (1.02e-3)" "potential prognostic unfavorable (3.06e-4)" "unprognostic (1.26e-1)" "unprognostic (2.98e-2)" "unprognostic (9.85e-2)" "unprognostic (2.16e-1)" "unprognostic (3.76e-2)" "unprognostic (2.85e-1)" "unprognostic (1.64e-2)" "unprognostic (7.30e-3)" "unprognostic (1.82e-1)" "unprognostic (7.24e-3)" "unprognostic (1.45e-1)" "unprognostic (1.24e-2)" "unprognostic (2.72e-2)" "unprognostic (8.72e-2)" "unprognostic (9.63e-3)" "unprognostic (1.36e-2)" LCMT2 "KIAA0547, MGC9534, PPM2, TYW4" ENSG00000168806 "Leucine carboxyl methyltransferase 2" O60294 15 43323649-43330582 "Enzymes, Plasma proteins, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 26.0;Esophageal apical cells: 14.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" HPA039401 Approved Approved Cytosol NA NA "Cluster 18: Non-specific - Translation" "Cluster 22: Epididymis - Mixed function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 58: Non-specific - Nuclear processes" "Cluster 3: Early primary spermatocytes - Early meiosis" 7 Cytosol "HPA039401: " "unprognostic (2.32e-2)" "unprognostic (2.21e-2)" "unprognostic (1.09e-1)" "unprognostic (1.75e-1)" "unprognostic (2.69e-1)" "unprognostic (2.63e-2)" "unprognostic (3.79e-1)" "unprognostic (3.37e-2)" "unprognostic (3.22e-1)" "unprognostic (1.97e-2)" "potential prognostic favorable (9.37e-8)" "unprognostic (2.24e-3)" "unprognostic (3.88e-2)" "unprognostic (1.34e-1)" "unprognostic (1.98e-1)" "unprognostic (6.69e-2)" "unprognostic (7.29e-2)" "unprognostic (1.26e-1)" "potential prognostic favorable (3.32e-4)" "unprognostic (8.94e-2)" "unprognostic (4.11e-1)" "unprognostic (8.14e-3)" "unprognostic (6.56e-2)" "unprognostic (9.24e-2)" "unprognostic (6.50e-3)" "unprognostic (1.21e-1)" "unprognostic (1.27e-1)" "unprognostic (3.46e-2)" "unprognostic (3.30e-2)" "unprognostic (9.91e-2)" "unprognostic (2.53e-1)" LCN1 "MGC71975, PMFA, TLC, TP, VEGP" ENSG00000160349 "Lipocalin 1" P31025 9 135521438-135526540 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Sensory transduction, Taste, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 12.5;seminal vesicle: 7.5" "Cell type enriched" "Detected in some" 49 "Lacrimal acinar cells: 24711.9" "Cell type enhanced" "Detected in some" "hippocampal CA4: 2.7;pericyte: 2.2" "Cancer enhanced" "Detected in some" "Ovary Serous Cystadenocarcinoma (TCGA): 3.9;Pancreatic Adenocarcinoma (TCGA): 2.2" "Region enhanced" "Detected in single" "hippocampal formation: 1.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "thyroid cancer: 1.6" "Not detected" "Not detected" "Secreted in other tissues" Transport NA NA 5100000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 29: Forebrain - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 30 "potential prognostic unfavorable (7.60e-4)" "unprognostic (2.13e-2)" "unprognostic (8.60e-2)" LCN10 ENSG00000187922 "Lipocalin 10" Q6JVE6 9 136738167-136743356 "Predicted secreted proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 30.5" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "endothelial cell: 2.8;leukocyte: 1.5;vascular associated smooth muscle cell: 1.3" "Cancer enriched" "Detected in some" 7 "Thyroid Carcinoma (TCGA): 13.5" "Not detected" "Not detected" "Group enriched" "Detected in some" 18 "memory B-cell: 6.5;naive B-cell: 6.4" "Lineage enriched" "Detected in single" 18 "B-cells: 6.5" "Cancer enhanced" "Detected in single" "Leukemia: 1.9" "Spleen - B-cells (Spleen)" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA055919 Approved "Secreted in male reproductive system" Transport NA NA "Cluster 34: B-cells - Unknown function" "Cluster 22: Epididymis - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 104: Brain endothelial cells - Blood brain barrier" "HPA055919: " "potential prognostic favorable (5.38e-4)" "unprognostic (1.99e-1)" "unprognostic (3.77e-1)" "unprognostic (2.21e-1)" LCN12 MGC48935 ENSG00000184925 "Lipocalin 12" Q6JVE5 9 136949551-136955497 "Predicted intracellular proteins, Predicted secreted proteins" Transport "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 11 "epididymis: 75.0" "Cell type enriched" "Detected in many" 11 "Epididymal principal cells: 2624.3" "Cell type enhanced" "Detected in many" "astrocyte: 45.5;choroid plexus epithelial cell: 24.7" "Cancer enriched" "Detected in some" 9 "Thyroid Carcinoma (TCGA): 30.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" Transport NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 3: Choroid plexus - Cilium" "Cluster 15: Kidney cancer - Membrane components" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" "unprognostic (2.36e-1)" "unprognostic (1.05e-2)" "unprognostic (8.00e-2)" "unprognostic (4.04e-1)" "unprognostic (3.75e-2)" "unprognostic (1.68e-2)" "unprognostic (4.86e-1)" LCN15 "PRO6093, UNQ2541" ENSG00000177984 "Lipocalin 15" Q6UWW0 9 136759634-136766255 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 11.2;seminal vesicle: 3.1" "Cell type enriched" "Detected in some" 25 "Neuroendocrine cells: 1256.0" "Cell type enhanced" "Detected in some" "deep-layer intratelencephalic: 3.0;hippocampal CA4: 2.7;upper-layer intratelencephalic: 4.4" "Group enriched" "Detected in many" 15 "Colon Adenocarcinoma (TCGA): 87.9;Rectum Adenocarcinoma (TCGA): 134.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "colorectal cancer: 15.7;liver cancer: 19.1;lung cancer: 5.9" "Low region specificity" "Detected in all" HPA060584 Enhanced "Secreted in other tissues" "No annotated function" NA NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" "HPA060584: " "unprognostic (1.92e-1)" "potential prognostic favorable (6.68e-4)" "unprognostic (4.52e-2)" "unprognostic (5.08e-2)" "unprognostic (5.90e-1)" "unprognostic (3.32e-1)" "unprognostic (4.19e-1)" LCN2 "24p3, NGAL" ENSG00000148346 "Lipocalin 2" P80188 9 128149071-128153453 "Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Apoptosis, Immunity, Innate immunity, Ion transport, Iron transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 2617.2;gallbladder: 2090.7;salivary gland: 1266.0" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 8399.9;Endometrial secretory cells: 17173.2;Esophageal apical cells: 9320.0;Lacrimal acinar cells: 3931.3;Neutrophil progenitors: 3018.0;Prostatic club cells: 6844.9;Respiratory deuterosomal cells: 3496.5;Respiratory secretory cells: 3151.1;Salivary basal cells: 2566.4;Salivary duct cells: 4478.4;Salivary ionocytes: 2296.9;Submucosal glandular cells: 3734.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Stomach Adenocarcinoma (TCGA): 2769.6" "Region enriched" "Detected in single" 5 "choroid plexus: 4.2" "Group enriched" "Detected in some" 88 "basophil: 9.7;neutrophil: 11.9;non-classical monocyte: 4.7" "Group enriched" "Detected in many" 84 "granulocytes: 11.9;monocytes: 4.7" "Cancer enhanced" "Detected in many" "Bile duct cancer: 2754.0;pancreatic cancer: 1459.4" "Prostate - Urothelial cells" "Low region specificity" "Detected in some" "Group enriched" "Detected in all" 6 "cerebellum: 275.8;spinal cord: 180.6" "HPA002695, CAB016549, CAB016550" Enhanced Supported "Endoplasmic reticulum" "Secreted in other tissues" Transport NA NA 120000000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 49 "Endoplasmic reticulum" "CAB016549: , CAB016550: , HPA002695: " "unprognostic (2.10e-1)" "unprognostic (1.88e-3)" "unprognostic (4.91e-2)" "unprognostic (1.95e-1)" "unprognostic (4.47e-1)" "unprognostic (1.15e-1)" "unprognostic (4.79e-2)" "unprognostic (1.32e-1)" "potential prognostic unfavorable (7.35e-5)" "unprognostic (1.15e-1)" "unprognostic (2.62e-3)" "unprognostic (1.35e-1)" "unprognostic (1.48e-2)" "unprognostic (1.74e-1)" "unprognostic (8.65e-2)" "unprognostic (2.60e-1)" "potential prognostic unfavorable (6.82e-4)" "unprognostic (1.56e-1)" "unprognostic (6.97e-3)" "unprognostic (1.65e-2)" "unprognostic (1.44e-1)" "unprognostic (6.23e-2)" "unprognostic (1.52e-1)" "unprognostic (2.84e-2)" "unprognostic (2.93e-1)" "unprognostic (8.08e-2)" "unprognostic (2.62e-1)" "unprognostic (2.86e-2)" "unprognostic (1.88e-1)" LCN6 ENSG00000267206 "Lipocalin 6" P62502 9 136744017-136748525 "Predicted intracellular proteins, Predicted secreted proteins" Fertilization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 64 "epididymis: 1493.0" "Cell type enriched" "Detected in some" 69 "Epididymal principal cells: 4552.3" "Cell type enriched" "Detected in single" 12 "endothelial cell: 1.9" "Cancer enriched" "Detected in some" 12 "Thyroid Carcinoma (TCGA): 38.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 13 "Leukemia: 31.7" "Pituitary gland - Endothelial cells, Spleen - Fibroblasts_2, Testis - Endothelial cells" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" Other NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 47: Endothelial cells - Vasculature" "Cluster 35: RS4;11 - Unknown function" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 13 "unprognostic (7.32e-2)" "unprognostic (4.90e-2)" "unprognostic (3.75e-3)" "unprognostic (7.19e-1)" LCN8 LCN5 ENSG00000204001 "Lipocalin 8" Q6JVE9 9 136754386-136758543 "Predicted intracellular proteins, Predicted secreted proteins" Transport "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 42 "epididymis: 79.3" "Cell type enriched" "Detected in some" 5 "Epididymal principal cells: 2176.1" "Group enriched" "Detected in some" 8 "hippocampal CA4: 3.4;upper rhombic lip: 5.7" "Cancer enriched" "Detected in single" 6 "Thyroid Carcinoma (TCGA): 1.5" "Region enriched" "Detected in single" 7 "cerebellum: 1.8" "Group enriched" "Detected in some" 60 "memory B-cell: 4.1;naive B-cell: 8.2" "Lineage enriched" "Detected in single" 79 "B-cells: 8.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" Transport NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 35: Non-specific - DNA binding" "Cluster 6: Leukemia - Signal transduction" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" "unprognostic (3.37e-1)" LCN9 ENSG00000148386 "Lipocalin 9" 9 135663309-135666961 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 11 "Epididymal principal cells: 24.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA060941 Enhanced "Secreted in male reproductive system" NA NA "Cluster 34: Testis cancer - Unknown function" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" "HPA060941: " LCNL1 FLJ45224 ENSG00000214402 "Lipocalin like 1" Q6ZST4 9 136981904-136986410 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 2.2;testis: 1.6" "Cell type enhanced" "Detected in some" "Astrocytes: 156.6;Bergmann glia: 53.5;Epididymal principal cells: 21.4;Leydig cells: 87.1;Müller glia: 46.1;Oligodendrocytes: 22.4;pDCs: 21.6;Peritubular myoid cells: 159.7;Podocytes: 47.2;Retinal pigment epithelial cells: 59.7;Sertoli cells: 36.4" "Cell type enhanced" "Detected in many" "astrocyte: 183.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Smooth muscle cells, Kidney - Podocytes, Stomach - Fibroblasts" "Low region specificity" "Detected in all" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 15: Kidney cancer - Membrane components" "Cluster 94: Gonadal somatic cells - Mixed function" "unprognostic (5.22e-2)" "unprognostic (3.38e-1)" LCOR "C10orf12, DKFZP564P1916, FLJ13022, FLJ38026, KIAA1795, MLR2" ENSG00000196233 "Ligand dependent nuclear receptor corepressor" Q96JN0 10 96832254-96995956 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 24.1" "Cell type enhanced" "Detected in all" "Neutrophils: 650.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031429, HPA057621, HPA077000" Approved Enhanced Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 25: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 24: Neutrophils - Innate immunity signal integration" 30 Nucleoplasm "HPA031429: , HPA057621: , HPA077000: " "unprognostic (2.73e-2)" "unprognostic (5.58e-2)" "unprognostic (3.51e-1)" "unprognostic (1.40e-1)" "unprognostic (2.37e-1)" "unprognostic (4.01e-2)" "unprognostic (1.55e-1)" "unprognostic (4.08e-3)" "unprognostic (2.01e-1)" "unprognostic (2.82e-2)" "potential prognostic favorable (2.25e-4)" "unprognostic (2.17e-2)" "unprognostic (1.57e-1)" "unprognostic (2.76e-3)" "unprognostic (1.37e-1)" "unprognostic (1.98e-1)" "unprognostic (2.89e-2)" "unprognostic (3.70e-2)" "unprognostic (2.91e-1)" "unprognostic (4.33e-2)" "unprognostic (4.64e-3)" "unprognostic (3.72e-2)" "unprognostic (1.88e-2)" "unprognostic (1.95e-2)" "unprognostic (8.90e-2)" "unprognostic (6.34e-2)" "unprognostic (3.84e-1)" "unprognostic (6.25e-2)" "unprognostic (1.46e-1)" "unprognostic (1.43e-1)" "unprognostic (1.39e-1)" LCORL "FLJ30696, MLR1" ENSG00000178177 "Ligand dependent nuclear receptor corepressor like" Q8N3X6 4 17841187-18021876 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028794, HPA028795, HPA060033" Uncertain Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 42: Retina - Visual perception" "Cluster 25: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" 6 Nucleoplasm "Nuclear membrane" "HPA028794: , HPA028795: , HPA060033: " "unprognostic (2.80e-1)" "unprognostic (3.04e-1)" "unprognostic (8.28e-3)" "unprognostic (1.47e-1)" "unprognostic (4.45e-2)" "unprognostic (8.54e-2)" "unprognostic (2.52e-1)" "unprognostic (1.75e-2)" "unprognostic (5.66e-2)" "unprognostic (2.27e-3)" "unprognostic (2.93e-3)" "unprognostic (9.25e-3)" "unprognostic (3.69e-1)" "validated prognostic unfavorable (3.96e-4)" "validated prognostic unfavorable (2.97e-4)" "unprognostic (3.16e-1)" "unprognostic (3.34e-2)" "unprognostic (1.87e-1)" "unprognostic (5.70e-3)" "unprognostic (1.40e-1)" "unprognostic (3.00e-1)" "unprognostic (2.83e-1)" "unprognostic (2.22e-1)" "unprognostic (3.77e-2)" "unprognostic (1.63e-2)" "unprognostic (5.90e-2)" "unprognostic (1.23e-2)" "unprognostic (2.84e-2)" "unprognostic (1.86e-2)" "unprognostic (1.96e-2)" "unprognostic (1.79e-1)" LCP1 "CP64, L-PLASTIN, LC64P, PLS2" ENSG00000136167 "Lymphocyte cytosolic protein 1" P13796 13 46125920-46211871 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 669.6;epididymis: 380.4;lymphoid tissue: 566.7" "Cell type enhanced" "Detected in many" "cDC: 637.7;Epididymal principal cells: 754.0;Kupffer cells: 562.7;Late spermatids: 534.6;Monocyte progenitors: 1308.9;monocytes: 1174.8;Neutrophil progenitors: 1996.1;Neutrophils: 6753.3;NK-cells: 569.2" "Cell type enriched" "Detected in many" 4 "leukocyte: 549.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 582.6;lymphoma: 986.4" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Lung - Neutrophils_2, Minor Salivary Gland - Macrophages, Pituitary gland - Macrophages, Prostate - Prostate glandular cells, Skeletal muscle - Macrophages, Skin - Langerhans cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000895, HPA019493, CAB020673" Enhanced Supported "Plasma membrane,Actin filaments,Cytosol" NA NA 770000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 55: Lymphoma - Immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 20 "Plasma membrane" "Actin filaments, Cytosol" "CAB020673: , HPA000895: , HPA019493: " "unprognostic (6.48e-2)" "unprognostic (1.11e-2)" "unprognostic (5.99e-3)" "unprognostic (6.13e-2)" "unprognostic (1.71e-2)" "unprognostic (1.20e-1)" "unprognostic (5.10e-2)" "unprognostic (1.14e-1)" "unprognostic (5.92e-2)" "unprognostic (5.42e-2)" "unprognostic (6.51e-2)" "unprognostic (2.73e-1)" "unprognostic (5.43e-2)" "unprognostic (1.82e-1)" "unprognostic (2.44e-1)" "unprognostic (3.43e-3)" "unprognostic (3.44e-2)" "unprognostic (7.19e-2)" "unprognostic (2.97e-1)" "unprognostic (3.18e-1)" "unprognostic (1.71e-1)" "unprognostic (2.74e-2)" "potential prognostic unfavorable (7.47e-4)" "unprognostic (1.24e-1)" "unprognostic (5.28e-2)" "unprognostic (3.77e-2)" "unprognostic (4.14e-3)" "unprognostic (1.74e-1)" "unprognostic (9.42e-2)" "unprognostic (7.22e-2)" "unprognostic (2.50e-1)" LCP2 "SLP-76, SLP76" ENSG00000043462 "Lymphocyte cytosolic protein 2" Q13094 5 170246233-170297815 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 154.8;lymphoid tissue: 107.3" "Cell type enriched" "Detected in many" 4 "Neutrophils: 3948.6" "Group enriched" "Detected in many" 7 "central nervous system macrophage: 147.1;leukocyte: 291.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in some" 4 "Leukemia: 90.8" "Adrenal gland - Macrophages, Minor Salivary Gland - Macrophages, Spleen - Macrophages, Thyroid gland - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004574, HPA036396, HPA036397" Enhanced Supported Cytosol NA NA 1300000 "Cluster 45: Eosinophils - Unknown function" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 49: HMC-1 - Innate immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 39 Cytosol "CAB004574: , HPA036396: , HPA036397: " "unprognostic (5.23e-2)" "unprognostic (3.60e-2)" "unprognostic (1.99e-1)" "unprognostic (1.71e-1)" "unprognostic (5.56e-2)" "unprognostic (1.27e-1)" "unprognostic (1.49e-1)" "unprognostic (2.07e-1)" "unprognostic (1.00e-2)" "unprognostic (3.90e-1)" "unprognostic (6.89e-3)" "unprognostic (1.81e-1)" "unprognostic (9.72e-2)" "unprognostic (1.09e-1)" "unprognostic (6.21e-2)" "unprognostic (3.47e-2)" "unprognostic (1.86e-3)" "unprognostic (1.32e-1)" "unprognostic (3.98e-1)" "unprognostic (8.23e-2)" "unprognostic (2.37e-1)" "unprognostic (1.92e-1)" "unprognostic (7.44e-2)" "unprognostic (3.06e-1)" "unprognostic (9.20e-2)" "unprognostic (1.10e-1)" "unprognostic (1.22e-1)" "unprognostic (7.34e-2)" "unprognostic (1.85e-2)" "unprognostic (8.95e-2)" "unprognostic (5.43e-2)" LCT ENSG00000115850 Lactase P09848 2 135787850-135837184 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Glycosidase, Hydrolase, Multifunctional enzyme" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 189 "intestine: 212.7" "Cell type enhanced" "Detected in some" "Early spermatids: 3.6;Enteric stem cells: 2.4;Enteric transient amplifying cells: 4.0;Enterocytes: 3.1;Epicardial cells: 2.3;Hepatic stellate cells: 6.5;Late primary spermatocytes: 2.8;Mesothelial cells: 2.3;Paneth cells: 3.9;Thymocytes: 5.1" "Cell type enhanced" "Detected in single" "hippocampal CA1-3: 2.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in some" 15 "hippocampal formation: 15.8" "Not detected" "Not detected" NA NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" LCTL "FLJ33279, KLG, KLPH" ENSG00000188501 "Lactase like" Q6UWM7 15 66547179-66565998 "Cancer-related genes, Predicted membrane proteins" "Sensory transduction, Vision" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 4 "brain: 2.5" "Cell type enhanced" "Detected in some" "Astrocytes: 4.0;Differentiating spermatogonia: 2.7;Early spermatids: 8.4;Ependymal cells: 2.8;Late spermatids: 15.6;Undifferentiated spermatogonia: 2.9" "Cell type enhanced" "Detected in many" "astrocyte: 4.8" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 2.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 5.6;testis cancer: 6.1" "Colon - Enteric glia cells, Pituitary gland - Undifferentiated cells (Pituitary gland)" "Not detected" "Not detected" "Not detected" "Not detected" HPA071640 Approved "Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 69: Skin cancer - ECM organization" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "Plasma membrane" "Endoplasmic reticulum" "HPA071640: " "unprognostic (1.10e-3)" "unprognostic (2.04e-3)" "potential prognostic unfavorable (1.13e-4)" "unprognostic (1.92e-2)" "unprognostic (1.23e-2)" LDAF1 "promethin, TMEM159" ENSG00000011638 "Lipid droplet assembly factor 1" Q96B96 16 21158377-21180616 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 71.8;Distal convoluted tubule cells: 30.9;Esophageal apical cells: 52.4;Myonuclei: 26.8;Ocular epithelial cells: 28.2;Papillary tip epithelial cells: 31.2;Suprabasal keratinocytes: 23.7;Urothelial cells: 37.4" "Cell type enhanced" "Detected in many" "deep-layer near-projecting: 34.7;eccentric medium spiny neuron: 34.7;upper rhombic lip: 35.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatic stellate cells, Skeletal muscle - Skeletal myocytes, Skin - Keratinocyte (other), Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018033, HPA063509" Approved Approved Vesicles NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 24: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 55: Myocytes - Oxidative muscle function" 12 Vesicles "HPA018033: , HPA063509: " "unprognostic (2.08e-3)" "unprognostic (3.09e-3)" "unprognostic (1.21e-1)" "unprognostic (1.00e-1)" "unprognostic (1.27e-2)" "unprognostic (1.99e-1)" "unprognostic (2.00e-2)" "unprognostic (7.13e-3)" "unprognostic (4.89e-2)" "unprognostic (2.26e-1)" "potential prognostic favorable (4.98e-10)" "unprognostic (3.85e-2)" "unprognostic (6.24e-2)" "unprognostic (1.42e-1)" "unprognostic (2.08e-1)" "unprognostic (2.68e-1)" "unprognostic (5.45e-2)" "unprognostic (6.15e-2)" "unprognostic (7.23e-2)" "unprognostic (1.67e-3)" "unprognostic (8.40e-2)" "potential prognostic unfavorable (3.02e-5)" "unprognostic (2.29e-1)" "unprognostic (6.62e-2)" "unprognostic (1.36e-1)" "unprognostic (3.68e-1)" "unprognostic (8.20e-2)" "unprognostic (2.06e-1)" "unprognostic (2.89e-1)" "unprognostic (4.71e-2)" "unprognostic (1.94e-1)" LDAH "C2orf43, FLJ21820" ENSG00000118961 "Lipid droplet associated hydrolase" Q9H6V9 2 20684014-20823130 "Predicted intracellular proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skin - Mitotic cells (Skin)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034729, HPA034730" Approved NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "HPA034729: , HPA034730: " "unprognostic (3.51e-1)" "unprognostic (7.28e-2)" "unprognostic (1.56e-2)" "unprognostic (2.47e-2)" "unprognostic (8.50e-2)" "unprognostic (3.26e-2)" "unprognostic (7.42e-2)" "unprognostic (5.94e-2)" "unprognostic (2.44e-2)" "potential prognostic favorable (1.18e-7)" "unprognostic (6.02e-2)" "potential prognostic favorable (3.16e-4)" "potential prognostic unfavorable (4.33e-5)" "unprognostic (1.32e-2)" "unprognostic (1.54e-2)" "unprognostic (4.86e-3)" "unprognostic (1.54e-1)" "unprognostic (1.15e-1)" "unprognostic (8.25e-2)" "potential prognostic unfavorable (6.87e-4)" "unprognostic (1.95e-2)" "unprognostic (1.75e-1)" "unprognostic (3.05e-2)" "unprognostic (1.47e-1)" "unprognostic (1.62e-2)" "unprognostic (2.70e-1)" "unprognostic (1.00e-1)" "unprognostic (6.07e-2)" "unprognostic (2.70e-1)" LDB1 "CLIM2, NLI" ENSG00000198728 "LIM domain binding 1" Q86U70 10 102106489-102120368 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 131.5;Megakaryocyte-Erythroid progenitors: 91.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034488 Approved Approved Nucleoplasm NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 54: Non-specific - Ribosome" "Cluster 23: Choroid plexus - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 50 Nucleoplasm "HPA034488: " "unprognostic (2.32e-3)" "unprognostic (7.14e-2)" "unprognostic (3.95e-2)" "unprognostic (2.04e-3)" "unprognostic (8.47e-3)" "unprognostic (1.70e-1)" "unprognostic (2.64e-1)" "potential prognostic favorable (1.56e-4)" "unprognostic (2.20e-3)" "unprognostic (1.72e-1)" "unprognostic (5.93e-2)" "unprognostic (3.21e-2)" "unprognostic (4.13e-2)" "unprognostic (2.97e-3)" "unprognostic (1.65e-1)" "unprognostic (5.18e-3)" "unprognostic (4.41e-2)" "unprognostic (3.68e-3)" "unprognostic (1.52e-3)" "unprognostic (9.30e-2)" "unprognostic (4.75e-3)" "potential prognostic favorable (5.78e-4)" "unprognostic (6.78e-2)" "unprognostic (1.34e-1)" "unprognostic (3.13e-1)" "unprognostic (1.01e-1)" "unprognostic (1.29e-1)" "unprognostic (3.01e-2)" "unprognostic (4.88e-2)" "unprognostic (4.17e-2)" "unprognostic (2.95e-3)" LDB2 "CLIM1, LDB1" ENSG00000169744 "LIM domain binding 2" O43679 4 16501541-16898678 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 583.0;Brain inhibitory neurons: 408.7;Endometrial stromal cells: 319.6;Fibro-adipogenic progenitors: 598.9;Leydig cells: 325.3;Lymphatic endothelial cells: 1916.8;Peritubular myoid cells: 326.1;Pituicytes/FSCs: 406.0;Vascular endothelial cells: 2327.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 51.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 13 "NK-cell: 2.0" "Lineage enriched" "Detected in single" 13 "NK-cells: 2.0" "Cancer enriched" "Detected in many" 6 "Bone cancer: 28.6" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Pituitary gland - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017544, HPA068634" Supported Supported "Nucleoplasm,Nucleoli,Plasma membrane" No NA "Cluster 14: Non-specific - Unknown function" "Cluster 13: Lung - Secretion" "Cluster 53: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 30 "Nucleoplasm, Nucleoli" "Plasma membrane" "CAB017544: , HPA068634: " "unprognostic (8.44e-2)" "unprognostic (2.80e-1)" "unprognostic (4.11e-2)" "unprognostic (1.07e-1)" "unprognostic (4.28e-2)" "unprognostic (9.27e-2)" "unprognostic (8.08e-2)" "unprognostic (8.19e-2)" "unprognostic (2.17e-2)" "unprognostic (3.73e-1)" "validated prognostic favorable (4.47e-9)" "validated prognostic favorable (4.48e-4)" "unprognostic (4.27e-3)" "unprognostic (4.21e-3)" "potential prognostic favorable (4.34e-4)" "unprognostic (2.65e-2)" "unprognostic (3.10e-1)" "unprognostic (2.23e-2)" "unprognostic (1.18e-1)" "unprognostic (3.10e-2)" "unprognostic (3.36e-3)" "unprognostic (2.37e-2)" "unprognostic (2.09e-2)" "unprognostic (7.96e-2)" "unprognostic (7.41e-2)" "unprognostic (2.34e-1)" "potential prognostic unfavorable (3.56e-6)" "potential prognostic unfavorable (6.74e-4)" "unprognostic (2.75e-1)" "unprognostic (6.97e-2)" "unprognostic (8.40e-2)" LDB3 "CMD1C, KIAA0613, PDLIM6, ZASP" ENSG00000122367 "LIM domain binding 3" O75112 10 86666785-86736072 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cardiomyopathy, Disease variant, Myofibrillar myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 24 "heart muscle: 1170.6;skeletal muscle: 2717.5;tongue: 1686.1" "Group enriched" "Detected in many" 4 "Cardiomyocytes: 570.3;Myonuclei: 924.1;Oligodendrocytes: 297.4" "Group enriched" "Detected in all" 8 "committed oligodendrocyte precursor: 109.0;oligodendrocyte: 423.2;vascular associated smooth muscle cell: 187.0" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 9.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Adrenal gland - Smooth muscle cells, Heart muscle - Cardiomyocytes, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Spleen - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA048955 Supported Uncertain "Nucleoplasm,Focal adhesion sites,Cytosol" NA NA 440000 "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 30: White matter - Myelination" "Cluster 11: Neuronal - Sensory perception" "Cluster 55: Myocytes - Oxidative muscle function" 2 "Focal adhesion sites, Cytosol" Nucleoplasm "HPA048955: " "unprognostic (8.34e-2)" "unprognostic (1.66e-2)" "unprognostic (1.97e-1)" "unprognostic (1.15e-1)" "unprognostic (1.85e-1)" "unprognostic (6.06e-2)" "unprognostic (2.06e-1)" "potential prognostic favorable (2.49e-5)" "unprognostic (1.20e-2)" "unprognostic (2.30e-1)" "unprognostic (4.03e-3)" "unprognostic (9.00e-2)" "unprognostic (1.62e-1)" "unprognostic (3.73e-2)" "unprognostic (8.72e-2)" "unprognostic (1.06e-2)" "unprognostic (2.77e-2)" LDHA ENSG00000134333 "Lactate dehydrogenase A" P00338 11 18394560-18408425 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Cancer-related genes, Disease variant, FDA approved drug targets, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Megakaryocytes: 68.0;Ocular epithelial cells: 128.9;Other brain neurons: 90.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Neutrophils, Heart muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015336, CAB069404, HPA075026" Uncertain Enhanced Cytosol NA NA 160000000 "Cluster 33: Non-specific - ATP binding" "Cluster 24: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 98: Neurons - Neurotransmission & signaling" 38 Cytosol "CAB015336: , CAB069404: , HPA075026: " "unprognostic (2.96e-3)" "unprognostic (2.59e-1)" "unprognostic (2.42e-1)" "potential prognostic unfavorable (9.33e-4)" "unprognostic (2.29e-1)" "unprognostic (2.09e-1)" "potential prognostic unfavorable (1.84e-4)" "unprognostic (1.04e-2)" "unprognostic (2.21e-2)" "potential prognostic unfavorable (8.71e-7)" "potential prognostic favorable (1.22e-6)" "unprognostic (2.02e-1)" "unprognostic (1.26e-3)" "validated prognostic unfavorable (6.75e-9)" "validated prognostic unfavorable (4.81e-6)" "validated prognostic unfavorable (2.07e-7)" "validated prognostic unfavorable (7.09e-5)" "unprognostic (6.23e-2)" "unprognostic (2.83e-1)" "unprognostic (7.11e-2)" "unprognostic (4.23e-2)" "validated prognostic unfavorable (4.52e-6)" "validated prognostic unfavorable (7.22e-4)" "unprognostic (1.90e-3)" "unprognostic (4.76e-3)" "unprognostic (1.14e-1)" "unprognostic (2.63e-2)" "unprognostic (1.20e-2)" "unprognostic (1.00e-1)" "unprognostic (1.04e-1)" "unprognostic (2.23e-1)" LDHAL6A "LDH6A, MGC23940" ENSG00000166800 "Lactate dehydrogenase A like 6A" Q6ZMR3 11 18455824-18479601 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 8.6" "Cell type enriched" "Detected in many" 5 "Oocytes: 327.0" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 2.9" "Testis - Early spermatids" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 41: Oocytes - Oogenesis" 3 "unprognostic (1.98e-1)" "unprognostic (2.48e-1)" LDHAL6B "LDH6B, LDHAL6, LDHL" ENSG00000171989 "Lactate dehydrogenase A like 6B" Q9BYZ2 15 59206843-59208588 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 99 "testis: 38.0" "Group enriched" "Detected in some" 20 "Early primary spermatocytes: 59.8;Late primary spermatocytes: 197.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Spermatocytes" "Region enriched" "Detected in single" 6 "olfactory bulb: 1.3" HPA053962 Enhanced Approved Cytosol NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 11: White matter - Signal transduction" "Cluster 56: Non-specific - Sensory perception" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 24 Cytosol "HPA053962: " "unprognostic (8.32e-3)" "unprognostic (5.16e-2)" LDHB ENSG00000111716 "Lactate dehydrogenase B" P07195 12 21635342-21757857 "Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1824.5;kidney: 1610.4" "Cell type enriched" "Detected in many" 5 "Parietal cells: 1143.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "CAB004641, HPA019007" Enhanced Supported "Primary cilium,Cytosol" No No 390000000 "Cluster 39: T-cells - T-cell receptor" "Cluster 52: Non-specific - Cellular respiration" "Cluster 19: Astrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 39 Cytosol "Primary cilium" "CAB004641: , HPA019007: " "unprognostic (7.47e-2)" "unprognostic (3.29e-1)" "unprognostic (1.12e-1)" "unprognostic (1.95e-1)" "unprognostic (5.43e-2)" "unprognostic (4.39e-2)" "unprognostic (2.46e-3)" "unprognostic (1.52e-3)" "unprognostic (3.39e-3)" "unprognostic (4.03e-2)" "potential prognostic favorable (7.02e-5)" "unprognostic (1.27e-2)" "unprognostic (3.69e-1)" "unprognostic (3.71e-2)" "unprognostic (2.79e-1)" "potential prognostic unfavorable (8.99e-5)" "unprognostic (9.36e-2)" "unprognostic (2.94e-1)" "unprognostic (1.70e-1)" "unprognostic (1.86e-1)" "unprognostic (1.12e-2)" "unprognostic (1.67e-1)" "unprognostic (3.55e-3)" "unprognostic (2.22e-1)" "unprognostic (7.04e-3)" "unprognostic (3.09e-2)" "unprognostic (1.57e-1)" "unprognostic (2.13e-1)" "unprognostic (1.89e-1)" "unprognostic (2.89e-1)" "unprognostic (9.25e-2)" LDHC CT32 ENSG00000166796 "Lactate dehydrogenase C" P07864 11 18412318-18452063 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 179 "testis: 247.8" "Group enriched" "Detected in many" 6 "Early spermatids: 1059.7;Late primary spermatocytes: 4060.8" "Low cell type specificity" "Detected in single" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA045442 Enhanced Supported "Cytosol,Mid piece,Principal piece,End piece" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 48: Non-specific - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 15 Cytosol "Mid piece, Principal piece, End piece" "HPA045442: " "unprognostic (1.83e-1)" "unprognostic (1.96e-3)" "unprognostic (1.53e-1)" "unprognostic (1.46e-1)" "unprognostic (2.63e-1)" "unprognostic (2.27e-1)" "unprognostic (4.16e-1)" LDHD ENSG00000166816 "Lactate dehydrogenase D" Q86WU2 16 75111860-75116780 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 78.8;liver: 126.0" "Cell type enhanced" "Detected in many" "Breast lactating cells: 50.6;Colonocytes: 73.2;Esophageal apical cells: 40.8;Foveolar cells: 24.4;Hepatocytes: 94.7;Parietal cells: 58.3" "Cell type enhanced" "Detected in many" "Bergmann glia: 19.3" "Group enriched" "Detected in all" 4 "Kidney Chromophobe (TCGA): 85.9;Kidney Renal Papillary Cell Carcinoma (TCGA): 54.3;Liver Hepatocellular Carcinoma (TCGA): 46.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 11.0" "Group enriched" "Detected in many" 45 "granulocytes: 11.0;monocytes: 4.8" "Cancer enhanced" "Detected in many" "prostate cancer: 10.9" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041766, HPA048639, HPA066148" Enhanced Approved Mitochondria,Cytosol No NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 76: Non-specific - Metabolism" "Cluster 45: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" Cytosol Mitochondria "HPA041766: , HPA048639: , HPA066148: " "unprognostic (1.30e-1)" "unprognostic (4.84e-2)" "unprognostic (2.42e-2)" "unprognostic (3.60e-2)" "unprognostic (9.27e-2)" "unprognostic (1.97e-1)" "unprognostic (1.06e-1)" "unprognostic (1.80e-1)" "unprognostic (5.64e-2)" "unprognostic (3.40e-2)" "potential prognostic favorable (3.43e-9)" "unprognostic (2.45e-2)" "potential prognostic favorable (3.97e-5)" "potential prognostic favorable (5.89e-4)" "unprognostic (3.75e-3)" "unprognostic (7.01e-3)" "unprognostic (1.73e-3)" "unprognostic (3.65e-1)" "unprognostic (2.39e-1)" "unprognostic (1.10e-1)" "unprognostic (1.51e-1)" "unprognostic (1.90e-1)" "unprognostic (5.54e-2)" "unprognostic (4.22e-1)" "unprognostic (1.64e-1)" "unprognostic (8.88e-3)" "unprognostic (4.14e-2)" "unprognostic (1.84e-2)" "unprognostic (4.22e-2)" "unprognostic (6.23e-2)" "unprognostic (1.54e-1)" LDLR LDLCQ2 ENSG00000130164 "Low density lipoprotein receptor" P01130 19 11089462-11133820 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol metabolism, Endocytosis, Host-virus interaction, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" "Host cell receptor for virus entry, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 112.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 560.4;Alveolar cells type 2: 985.4;Neutrophils: 538.6;Salivary myoepithelial cells: 535.3;Transitional alveolar cells: 664.7" "Cell type enhanced" "Detected in all" "endothelial cell: 88.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 9 "basophil: 46.2" "Lineage enriched" "Detected in many" 9 "granulocytes: 46.2" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Colon - Neutrophils, Heart muscle - Endothelial cells, Minor Salivary Gland - Minor salivary gland basal cells, Testis - Leydig cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009647, HPA009974, HPA013159" Approved Approved Vesicles NA NA 11000000 "Cluster 41: Basophils - Unknown function" "Cluster 28: Liver & Adrenal gland - Secretion" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 31 Vesicles "HPA009647: , HPA009974: , HPA013159: " "unprognostic (1.57e-1)" "unprognostic (3.00e-1)" "unprognostic (5.06e-1)" "unprognostic (1.20e-3)" "unprognostic (2.01e-2)" "unprognostic (1.11e-2)" "unprognostic (7.90e-2)" "unprognostic (5.10e-2)" "unprognostic (2.47e-1)" "unprognostic (2.77e-1)" "unprognostic (2.22e-1)" "unprognostic (2.12e-1)" "unprognostic (2.19e-3)" "unprognostic (4.17e-2)" "unprognostic (8.57e-2)" "unprognostic (1.85e-2)" "unprognostic (4.92e-2)" "unprognostic (1.07e-1)" "unprognostic (1.13e-1)" "unprognostic (2.56e-2)" "unprognostic (3.99e-1)" "potential prognostic unfavorable (9.21e-5)" "unprognostic (1.92e-1)" "unprognostic (2.08e-1)" "unprognostic (6.71e-2)" "unprognostic (9.18e-3)" "unprognostic (1.09e-1)" "unprognostic (5.24e-2)" "unprognostic (1.02e-1)" "unprognostic (1.38e-1)" "unprognostic (7.64e-2)" LDLRAD1 ENSG00000203985 "Low density lipoprotein receptor class A domain containing 1" Q5T700 1 54007298-54018186 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "fallopian tube: 109.3" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 129.4;Epididymal efferent duct ciliated cells: 93.2;Fallopian tube ciliated cells: 428.3;Respiratory ciliated cells: 370.7" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 8.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adrenal gland - Adrenal cortex cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA052489 Enhanced Approved "Nucleoplasm,Golgi apparatus,Primary cilium" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 48: Non-specific - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" 85 Nucleoplasm "Golgi apparatus, Primary cilium" "HPA052489: " "potential prognostic favorable (8.07e-4)" "unprognostic (1.78e-2)" "unprognostic (2.43e-1)" "unprognostic (1.74e-1)" "unprognostic (2.16e-1)" "unprognostic (2.98e-1)" "unprognostic (2.20e-1)" "unprognostic (2.60e-1)" "unprognostic (1.77e-1)" "unprognostic (1.12e-1)" "unprognostic (2.49e-1)" "unprognostic (9.97e-3)" "unprognostic (7.77e-2)" "unprognostic (8.11e-2)" "unprognostic (3.76e-2)" LDLRAD2 ENSG00000187942 "Low density lipoprotein receptor class A domain containing 2" Q5SZI1 1 21812265-21825225 "Predicted secreted proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 34.8;Cardiomyocytes: 108.3;Ependymal cells: 24.6;Epicardial cells: 56.9;Epididymal efferent duct ciliated cells: 18.5;Fibro-adipogenic progenitors: 17.2;Fibroblasts: 28.8;Vascular endothelial cells: 44.9;Vascular smooth muscle cells: 19.3" "Cell type enriched" "Detected in some" 12 "ependymal cell: 31.7" "Group enriched" "Detected in some" 31 "Prostate Adenocarcinoma (TCGA): 24.3;Uterine Corpus Endometrial Carcinoma (TCGA): 53.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 2.2" "Liver - Vascular endothelial cells, Minor Salivary Gland - Minor salivary glandular cells" "Not detected" "Not detected" "Group enriched" "Detected in some" 20 "basal ganglia: 5.3;midbrain: 7.9" HPA030478 Approved "Secreted - unknown location" Receptor NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 46: Brainstem - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "HPA030478: " "unprognostic (1.92e-1)" "unprognostic (2.58e-2)" "unprognostic (1.15e-1)" "unprognostic (1.39e-2)" "unprognostic (3.37e-2)" "unprognostic (6.86e-2)" "unprognostic (1.07e-1)" "unprognostic (2.73e-1)" "unprognostic (1.42e-1)" LDLRAD3 LRAD3 ENSG00000179241 "Low density lipoprotein receptor class A domain containing 3" Q86YD5 11 35943981-36232136 "Predicted membrane proteins" "Host-virus interaction" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 28.1" "Cell type enhanced" "Detected in many" "Adipocytes: 352.7;Bergmann glia: 478.7;Myosatellite cells: 280.1;Oligodendrocyte progenitor cells: 437.0;Oligodendrocytes: 251.8;Prostatic glandular cells: 357.9;Salivary acinar cells: 434.0;Thymic myoid cells: 300.5" "Cell type enhanced" "Detected in many" "endothelial cell: 563.6;fibroblast: 579.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 4.8;non-classical monocyte: 6.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038251 Approved Approved "Cell Junctions" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 69: Skin cancer - ECM organization" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" "Cell Junctions" "HPA038251: " "unprognostic (5.55e-2)" "unprognostic (6.45e-3)" "unprognostic (1.14e-1)" "unprognostic (2.03e-3)" "unprognostic (4.16e-3)" "unprognostic (2.48e-1)" "unprognostic (9.63e-2)" "unprognostic (2.90e-1)" "unprognostic (2.20e-1)" "unprognostic (8.37e-3)" "unprognostic (1.12e-1)" "unprognostic (1.39e-2)" "unprognostic (7.10e-3)" "unprognostic (1.88e-2)" "unprognostic (7.96e-3)" "potential prognostic unfavorable (1.61e-9)" "unprognostic (1.19e-1)" "unprognostic (2.17e-1)" "unprognostic (1.86e-1)" "unprognostic (5.73e-2)" "unprognostic (1.26e-1)" "unprognostic (6.00e-2)" "unprognostic (6.53e-3)" "unprognostic (6.56e-2)" "unprognostic (7.71e-2)" "unprognostic (2.29e-2)" "unprognostic (1.03e-1)" "unprognostic (4.99e-2)" "unprognostic (1.62e-1)" "unprognostic (3.87e-2)" "unprognostic (4.01e-2)" LDLRAD4 C18orf1 ENSG00000168675 "Low density lipoprotein receptor class A domain containing 4" O15165 18 13217498-13652755 "Predicted intracellular proteins, Predicted membrane proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 56.3;lymphoid tissue: 42.1" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 2112.5;Cone photoreceptor cells: 1705.8;Microglia: 1783.7;Prostatic glandular cells: 1046.0;Thymocytes: 1652.4" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 2320.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Leukemia: 31.0;lymphoma: 18.6" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047633, HPA065246" Approved Supported Vesicles NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 43: Hindbrain - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" 4 Vesicles "HPA047633: , HPA065246: " "unprognostic (2.48e-3)" "unprognostic (1.44e-1)" "unprognostic (8.12e-3)" "unprognostic (5.20e-2)" "unprognostic (2.44e-2)" "unprognostic (1.64e-1)" "unprognostic (2.93e-3)" "unprognostic (1.90e-2)" "unprognostic (1.03e-1)" "validated prognostic favorable (2.67e-6)" "validated prognostic favorable (3.17e-4)" "unprognostic (1.62e-1)" "unprognostic (2.00e-1)" "potential prognostic favorable (5.24e-4)" "unprognostic (1.19e-1)" "unprognostic (1.72e-2)" "unprognostic (2.17e-1)" "unprognostic (4.04e-2)" "unprognostic (6.49e-3)" "unprognostic (1.20e-1)" "unprognostic (7.50e-2)" "unprognostic (1.64e-1)" "unprognostic (1.72e-2)" "unprognostic (9.83e-2)" "unprognostic (2.77e-1)" "unprognostic (1.28e-1)" "unprognostic (4.10e-2)" "unprognostic (1.74e-2)" "unprognostic (1.27e-2)" LDLRAP1 "ARH, ARH2, DKFZp586D0624, FHCB1, FHCB2, MGC34705" ENSG00000157978 "Low density lipoprotein receptor adaptor protein 1" Q5SW96 1 25543606-25568886 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cholesterol metabolism, Endocytosis, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Atherosclerosis, Disease variant, Hyperlipidemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 79.7" "Cell type enriched" "Detected in many" 6 "Platelets: 537.4" "Cell type enhanced" "Detected in many" "oligodendrocyte: 98.1;upper rhombic lip: 65.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 7 "NK-cells: 39.5;T-cells: 107.5" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB003705, HPA050358" Uncertain Approved Microtubules NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 64: Non-specific - Transcription" "Cluster 30: White matter - Myelination" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 47: Platelets - Hemostasis" 22 Microtubules "CAB003705: , HPA050358: " "unprognostic (2.51e-2)" "unprognostic (1.12e-1)" "unprognostic (2.24e-1)" "unprognostic (4.38e-2)" "unprognostic (2.08e-2)" "unprognostic (1.10e-1)" "unprognostic (1.54e-1)" "unprognostic (8.28e-2)" "unprognostic (4.61e-2)" "unprognostic (3.09e-2)" "unprognostic (1.37e-2)" "unprognostic (2.61e-2)" "unprognostic (2.42e-2)" "unprognostic (9.81e-3)" "unprognostic (9.20e-3)" "unprognostic (1.07e-2)" "unprognostic (1.53e-1)" "unprognostic (1.52e-1)" "unprognostic (3.35e-1)" "unprognostic (3.52e-2)" "unprognostic (8.16e-2)" "unprognostic (1.05e-2)" "unprognostic (3.80e-2)" "unprognostic (1.70e-1)" "unprognostic (1.31e-1)" "unprognostic (3.41e-2)" "unprognostic (4.26e-3)" "unprognostic (3.62e-1)" "unprognostic (2.08e-1)" "unprognostic (1.24e-1)" "unprognostic (6.13e-2)" LDOC1 "BCUR1, Mar7, Mart7, RTL7, SIRH7" ENSG00000182195 "LDOC1 regulator of NFKB signaling" O95751 X 141111605-141177129 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 54.7" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 53.9;Oocytes: 59.9;Vascular smooth muscle cells: 61.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 6.4" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Somatotropes, Thyroid gland - Thyroid glandular cells" "Region enriched" "Detected in many" 5 "cerebellum: 19.2" "Low region specificity" "Detected in all" "HPA051768, HPA061842" Approved Supported Nucleoplasm,Nucleoli NA NA "Cluster 24: Non-specific - Transcription" "Cluster 74: Non-specific - Signal transduction" "Cluster 14: Neurons - Synaptic function" "Cluster 36: Non-specific - mRNA processing" "Cluster 62: Smooth muscle cells - Muscle contraction" 99 "Nucleoplasm, Nucleoli" "HPA051768: , HPA061842: " "unprognostic (1.45e-1)" "unprognostic (4.33e-2)" "unprognostic (4.59e-1)" "unprognostic (1.74e-3)" "unprognostic (7.63e-2)" "unprognostic (9.33e-2)" "unprognostic (3.40e-1)" "unprognostic (1.07e-1)" "potential prognostic favorable (4.29e-5)" "unprognostic (1.09e-2)" "unprognostic (5.88e-2)" "unprognostic (8.28e-3)" "potential prognostic favorable (1.23e-4)" "unprognostic (2.51e-2)" "potential prognostic unfavorable (5.96e-4)" "unprognostic (7.02e-2)" "unprognostic (1.74e-2)" "unprognostic (7.08e-2)" "unprognostic (3.30e-2)" "unprognostic (2.04e-2)" "unprognostic (1.16e-1)" "unprognostic (1.63e-1)" "unprognostic (2.11e-1)" "unprognostic (1.14e-1)" "unprognostic (2.27e-2)" "unprognostic (1.70e-1)" "unprognostic (5.00e-2)" "unprognostic (1.56e-1)" LEAP2 LEAP-2 ENSG00000164406 "Liver enriched antimicrobial peptide 2" Q969E1 5 132873444-132875046 "Plasma proteins, Predicted secreted proteins" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 22 "liver: 496.1" "Cell type enriched" "Detected in many" 7 "Hepatocytes: 1981.7" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in some" 31 "Liver Hepatocellular Carcinoma (TCGA): 145.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted to blood" Defense NA NA 1600000 "Cluster 20: Non-specific - DNA binding" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 48: Non-specific - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 93: Hepatocytes - Bile production & excretion" 4 "unprognostic (1.98e-1)" "unprognostic (1.75e-1)" "unprognostic (3.45e-3)" "unprognostic (1.17e-2)" "potential prognostic favorable (2.97e-5)" "unprognostic (3.44e-3)" "unprognostic (2.42e-1)" "unprognostic (4.79e-3)" "potential prognostic favorable (4.09e-6)" "unprognostic (7.54e-2)" "unprognostic (2.66e-1)" "unprognostic (1.90e-2)" "unprognostic (3.69e-2)" "unprognostic (4.29e-2)" LECT2 "chm-II, chm2" ENSG00000145826 "Leukocyte cell derived chemotaxin 2" O14960 5 135922279-135954983 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Chemotaxis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 53 "liver: 445.4" "Cell type enhanced" "Detected in some" "Early spermatids: 152.1;Hepatocytes: 107.3;Late primary spermatocytes: 103.5;Late spermatids: 63.8;Retinal horizontal cells: 28.0" "Cell type enhanced" "Detected in some" "eccentric medium spiny neuron: 14.0;midbrain-derived inhibitory: 9.2" "Cancer enriched" "Detected in some" 55 "Liver Hepatocellular Carcinoma (TCGA): 101.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Liver - Hepatocytes, Prostate - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA043883, HPA058246" Enhanced Supported Vesicles,Cytosol "Secreted to blood" Other NA NA 26500000 1900000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 56: Non-specific - Sensory perception" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" Cytosol Vesicles "HPA043883: , HPA058246: " "unprognostic (1.03e-2)" "unprognostic (1.60e-1)" "potential prognostic favorable (6.89e-5)" "unprognostic (8.75e-3)" "unprognostic (1.96e-1)" "unprognostic (4.30e-2)" "unprognostic (1.31e-1)" "unprognostic (1.09e-1)" "unprognostic (1.10e-1)" LEF1 "TCF10, TCF1ALPHA, TCF7L3" ENSG00000138795 "Lymphoid enhancer binding factor 1" Q9UJU2 4 108047545-108168956 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 27 "lymphoid tissue: 325.2" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 94.1;Choroid plexus epithelial cells: 264.9;Endometrial stromal cells: 73.6;Ependymal cells: 107.5;Melanocytes: 213.5;Pituicytes/FSCs: 72.1;Renal collecting duct intercalated cells: 255.8;T-cells: 142.3;Thymocytes: 347.2;Vascular endothelial cells: 82.3" "Cell type enhanced" "Detected in many" "endothelial cell: 1148.3;pericyte: 340.2" "Cancer enriched" "Detected in many" 5 "Skin Cutaneous Melanoma (TCGA): 54.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 143.0" "Lineage enriched" "Detected in many" 4 "T-cells: 143.0" "Cancer enhanced" "Detected in many" "Leukemia: 151.1" "Adrenal gland - Adrenal cortex cells, Skin - Inner root sheath cells, Spleen - T-cells, Testis - Early spermatids" "Region enhanced" "Detected in all" "thalamus: 22.6" "Low region specificity" "Detected in all" "HPA002087, CAB019405" Enhanced Approved Nucleoplasm NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 80: Thymus - Adaptive immune response" "Cluster 38: Sub-cortical - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 9: T-cells - Adaptive immunity: Regulation" 23 Nucleoplasm "CAB019405: , HPA002087: " "unprognostic (2.39e-1)" "unprognostic (1.94e-3)" "unprognostic (3.46e-2)" "unprognostic (3.60e-2)" "unprognostic (1.10e-1)" "unprognostic (1.42e-1)" "unprognostic (3.42e-1)" "unprognostic (3.80e-3)" "unprognostic (4.92e-2)" "unprognostic (3.11e-1)" "unprognostic (2.66e-2)" "unprognostic (5.73e-2)" "unprognostic (1.14e-2)" "unprognostic (3.88e-1)" "unprognostic (3.73e-2)" "potential prognostic unfavorable (6.48e-4)" "unprognostic (5.24e-2)" "unprognostic (7.55e-2)" "unprognostic (3.84e-1)" "unprognostic (2.73e-1)" "unprognostic (1.89e-1)" "unprognostic (3.82e-1)" "unprognostic (5.56e-2)" "unprognostic (1.76e-1)" "unprognostic (6.82e-2)" "unprognostic (2.98e-1)" "unprognostic (6.62e-2)" "unprognostic (4.58e-2)" "unprognostic (2.09e-2)" "unprognostic (2.84e-2)" LEFTY1 "LEFTB, LEFTYB" ENSG00000243709 "Left-right determination factor 1" O75610 1 225886282-225911382 "Predicted secreted proteins" "Cytokine, Developmental protein, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "intestine: 65.1;pancreas: 91.4" "Cell type enhanced" "Detected in many" "Colonocytes: 182.8;Endometrial ciliated cells: 103.4;Endometrial luminal cells: 414.3;Enteric stem cells: 384.2;Enteric transient amplifying cells: 190.1;Goblet cells: 52.9;Pancreatic duct cells: 178.8" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 91.6;Rectum Adenocarcinoma (TCGA): 132.5" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 51 "basophil: 16.9" "Lineage enriched" "Detected in single" 51 "granulocytes: 16.9" "Group enriched" "Detected in some" 5 "colorectal cancer: 10.0;Uterine cancer: 4.4" "Colon - Colon enterocytes, Minor Salivary Gland - Minor salivary gland ductal cells" "HPA047883, HPA056210" Approved "Secreted in other tissues" Cytokine NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 51: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" "HPA047883: , HPA056210: " "unprognostic (1.39e-1)" "unprognostic (2.63e-1)" "unprognostic (4.14e-3)" "unprognostic (3.22e-2)" "unprognostic (2.59e-1)" "unprognostic (2.48e-3)" "unprognostic (1.05e-1)" "potential prognostic unfavorable (2.53e-4)" "unprognostic (3.53e-2)" "unprognostic (2.26e-2)" "unprognostic (1.58e-1)" "unprognostic (1.87e-2)" "unprognostic (1.02e-1)" "unprognostic (8.54e-2)" "unprognostic (1.24e-1)" "unprognostic (2.03e-1)" "unprognostic (1.21e-1)" "unprognostic (2.44e-2)" "unprognostic (1.12e-1)" "unprognostic (2.91e-2)" LEFTY2 "EBAF, LEFTA, LEFTYA, TGFB4" ENSG00000143768 "Left-right determination factor 2" O00292 1 225936598-225941383 "Disease related genes, Predicted secreted proteins" "Cytokine, Developmental protein, Growth factor" "Disease variant, Heterotaxy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 89.0;endometrium 1: 160.0" "Cell type enhanced" "Detected in some" "Decidual stromal cells: 1.1;Endometrial stromal cells: 1.7;Erythrocytes: 1.5;Late spermatids: 1.0;Leydig cells: 1.6;Pituicytes/FSCs: 1.1" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 11 "Testicular Germ Cell Tumor (TCGA): 83.6" "Region enriched" "Detected in some" 20 "choroid plexus: 33.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "Myeloma: 17.9;testis cancer: 23.5" "Pituitary gland - Undifferentiated cells (Pituitary gland), Skeletal muscle - Fibroblasts, Spleen - Smooth muscle cells, Thyroid gland - Fibroblasts" "CAB025801, HPA047883, HPA056210" Approved "Secreted in other tissues" Cytokine NA NA 6100 "Cluster 75: Ovary - Mixed function" "Cluster 36: Choroid plexus - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 108: Fibroblasts - ECM organization" "CAB025801: , HPA047883: , HPA056210: " "unprognostic (8.95e-2)" "unprognostic (3.70e-1)" "unprognostic (1.69e-3)" "unprognostic (2.79e-1)" "unprognostic (2.42e-3)" "unprognostic (8.33e-2)" "unprognostic (4.23e-2)" "unprognostic (1.19e-1)" "unprognostic (5.15e-2)" "unprognostic (4.78e-1)" LEKR1 FLJ16641 ENSG00000197980 "Leucine, glutamate and lysine rich 1" Q6ZMV7 3 156825481-157046129 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "testis: 12.1" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 149.4;Ependymal cells: 297.0;Epicardial cells: 143.3;Fallopian tube ciliated cells: 145.8;Late primary spermatocytes: 226.7;Respiratory ciliated cells: 317.6;Thyrotrophs: 116.2" "Group enriched" "Detected in all" 4 "choroid plexus epithelial cell: 146.3;ependymal cell: 318.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044039, HPA047774" Uncertain Approved Nucleoplasm,Nucleoli NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 22: Epididymis - Mixed function" "Cluster 46: Brainstem - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 34: Ciliated cells - Cilia assembly & function" Nucleoplasm Nucleoli "HPA044039: , HPA047774: " "unprognostic (1.69e-1)" "unprognostic (1.78e-1)" "unprognostic (1.97e-2)" "unprognostic (1.24e-2)" "unprognostic (1.56e-1)" "unprognostic (5.68e-2)" "unprognostic (4.23e-2)" "potential prognostic favorable (5.38e-4)" "unprognostic (1.24e-1)" "unprognostic (7.72e-2)" "unprognostic (5.27e-2)" "unprognostic (2.18e-1)" "unprognostic (3.18e-2)" "unprognostic (3.59e-1)" "unprognostic (7.73e-2)" "unprognostic (1.24e-1)" "unprognostic (2.39e-3)" "unprognostic (3.70e-1)" LELP1 ENSG00000203784 "Late cornified envelope like proline rich 1" Q5T871 1 153203430-153205120 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1354 "testis: 1035.1" "Cell type enriched" "Detected in some" 9 "Late spermatids: 39637.1" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "Testicular Germ Cell Tumor (TCGA): 1.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA070231 Enhanced NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 14 "HPA070231: " "unprognostic (3.49e-1)" LEMD1 "CT50, LEMP-1" ENSG00000186007 "LEM domain containing 1" Q68G75 1 205381378-205455954 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "epididymis: 14.0;testis: 52.5" "Cell type enriched" "Detected in many" 5 "Late spermatids: 6870.8" "Cell type enhanced" "Detected in many" "lower rhombic lip: 47.5;thalamic excitatory: 20.1" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 32.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 18.4" "Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebellum: 1.1" HPA076708 Approved "Plasma membrane" NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 12 "Plasma membrane" "HPA076708: " "unprognostic (4.00e-2)" "unprognostic (2.30e-1)" "unprognostic (2.72e-1)" "unprognostic (3.84e-2)" "unprognostic (1.70e-2)" "unprognostic (2.57e-2)" "unprognostic (6.74e-2)" "unprognostic (3.92e-2)" "unprognostic (3.33e-1)" "unprognostic (5.49e-3)" "unprognostic (6.36e-2)" "unprognostic (1.57e-2)" "unprognostic (8.97e-2)" "unprognostic (6.39e-2)" "unprognostic (1.82e-1)" "unprognostic (1.03e-3)" "unprognostic (1.85e-2)" "potential prognostic unfavorable (1.10e-4)" "unprognostic (6.74e-2)" "unprognostic (2.86e-2)" "unprognostic (3.98e-2)" "unprognostic (2.08e-2)" "unprognostic (4.01e-2)" "unprognostic (1.13e-1)" "unprognostic (1.43e-1)" LEMD2 "dJ482C21.1, LEM2, NET25" ENSG00000161904 "LEM domain nuclear envelope protein 2" Q8NC56 6 33771202-33789130 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017340 Supported Supported "Nuclear membrane" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 28: Non-specific - Nuclear processes" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 12 "Nuclear membrane" "HPA017340: " "potential prognostic unfavorable (4.45e-4)" "unprognostic (1.81e-2)" "unprognostic (2.06e-1)" "unprognostic (3.04e-2)" "unprognostic (3.76e-2)" "unprognostic (7.87e-2)" "unprognostic (4.74e-2)" "unprognostic (3.92e-2)" "unprognostic (2.16e-2)" "unprognostic (1.52e-1)" "unprognostic (9.35e-2)" "unprognostic (1.84e-2)" "unprognostic (1.44e-1)" "unprognostic (5.06e-3)" "unprognostic (2.17e-2)" "unprognostic (3.40e-1)" "unprognostic (1.21e-1)" "unprognostic (4.14e-2)" "unprognostic (2.32e-2)" "unprognostic (2.78e-2)" "unprognostic (9.57e-3)" "potential prognostic favorable (2.18e-4)" "potential prognostic unfavorable (3.27e-5)" "unprognostic (1.76e-1)" "unprognostic (7.80e-3)" "unprognostic (8.49e-2)" "unprognostic (2.03e-1)" "unprognostic (3.17e-2)" "unprognostic (1.53e-1)" "unprognostic (1.67e-1)" "unprognostic (1.57e-1)" LEMD3 MAN1 ENSG00000174106 "LEM domain containing 3" Q9Y2U8 12 65169583-65248355 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophil progenitors: 245.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025078, HPA076986" Uncertain Supported "Nuclear membrane" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 6: Leukemia - Signal transduction" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 54 "Nuclear membrane" "HPA025078: , HPA076986: " "unprognostic (1.15e-1)" "unprognostic (2.09e-2)" "unprognostic (5.51e-2)" "unprognostic (2.26e-3)" "unprognostic (2.59e-2)" "unprognostic (2.05e-2)" "unprognostic (2.60e-1)" "unprognostic (1.00e-2)" "unprognostic (3.69e-1)" "unprognostic (2.23e-2)" "validated prognostic favorable (2.89e-5)" "validated prognostic favorable (1.77e-4)" "unprognostic (2.28e-1)" "unprognostic (3.11e-3)" "unprognostic (1.06e-1)" "unprognostic (2.05e-2)" "unprognostic (1.73e-1)" "unprognostic (1.23e-1)" "unprognostic (7.81e-3)" "unprognostic (5.12e-2)" "unprognostic (5.39e-2)" "unprognostic (9.50e-2)" "unprognostic (1.39e-3)" "unprognostic (1.05e-1)" "unprognostic (5.69e-2)" "unprognostic (1.48e-2)" "unprognostic (2.43e-2)" "unprognostic (8.35e-2)" "unprognostic (3.80e-1)" "unprognostic (1.05e-1)" "unprognostic (4.06e-2)" LENEP LEP503 ENSG00000163352 "Lens epithelial protein" Q9Y5L5 1 154993586-154994315 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "prostate cancer: 1.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 6: Non-specific - Immune response" "Cluster 60: Prostate cancer - Unknown function" "Cluster 11: Muller glia cells - Retinal homeostasis" 1 "unprognostic (3.50e-1)" "potential prognostic favorable (8.70e-4)" LENG1 ENSG00000105617 "Leukocyte receptor cluster member 1" Q96BZ8 19 54155161-54159721 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 63.9;Late primary spermatocytes: 92.9;Oocytes: 87.5" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in some" 11 "Prostate Adenocarcinoma (TCGA): 9.1;Uterine Corpus Endometrial Carcinoma (TCGA): 15.5" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in single" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043541 Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 68: Non-specific - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 32: Non-specific - Cell proliferation" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 76 "Plasma membrane" Nucleoplasm "HPA043541: " "unprognostic (2.12e-1)" "unprognostic (2.08e-1)" "unprognostic (2.26e-1)" "unprognostic (6.08e-2)" "unprognostic (1.45e-2)" "unprognostic (8.88e-2)" "unprognostic (1.67e-1)" "unprognostic (2.63e-2)" LENG8 "KIAA1932, MGC40108, pp13842" ENSG00000167615 "Leukocyte receptor cluster member 8" Q96PV6 19 54448887-54462016 "Essential proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 98.4;Bergmann glia: 79.2;Brain excitatory neurons: 76.0;Brain inhibitory neurons: 70.2;Choroid plexus epithelial cells: 191.6;Distal convoluted tubule cells: 98.3;Ependymal cells: 116.0;Loop of henle epithelial cells: 76.5;Microglia: 115.5;Oligodendrocyte progenitor cells: 76.3;Oligodendrocytes: 104.2;Other brain neurons: 65.5;Podocytes: 208.0;Proximal tubule cells: 113.7;Renal collecting duct intercalated cells: 106.0;Renal collecting duct principal cells: 70.3;Renal connecting tubule cells: 102.4;Tuft cells: 57.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042004, HPA061571" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 64: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 56: Non-specific - Sensory perception" "Cluster 102: Non-specific - Mixed function" 40 Nucleoplasm Cytosol "HPA042004: , HPA061571: " "unprognostic (2.00e-3)" "unprognostic (1.20e-1)" "unprognostic (4.55e-2)" "unprognostic (2.01e-2)" "potential prognostic unfavorable (8.57e-4)" "unprognostic (1.97e-1)" "unprognostic (7.19e-2)" "unprognostic (2.58e-1)" "unprognostic (2.51e-2)" "unprognostic (1.05e-1)" "potential prognostic unfavorable (4.99e-6)" "unprognostic (1.83e-1)" "unprognostic (1.50e-1)" "unprognostic (3.13e-2)" "unprognostic (1.35e-1)" "unprognostic (2.98e-1)" "unprognostic (6.84e-2)" "unprognostic (1.74e-1)" "unprognostic (1.99e-1)" "unprognostic (1.06e-1)" "unprognostic (1.70e-2)" "potential prognostic favorable (3.12e-4)" "potential prognostic unfavorable (2.12e-4)" "unprognostic (1.20e-1)" "unprognostic (1.47e-2)" "unprognostic (1.14e-1)" "unprognostic (9.65e-2)" "unprognostic (1.87e-1)" "unprognostic (1.94e-1)" "unprognostic (2.21e-1)" "unprognostic (1.90e-1)" LENG9 ENSG00000275183 "Leukocyte receptor cluster member 9" 19 54461732-54463778 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 28.4" "Cell type enhanced" "Detected in some" "Astrocytes: 4.6;Bergmann glia: 6.7;Brain excitatory neurons: 6.8;Brain inhibitory neurons: 5.1;Choroid plexus epithelial cells: 6.2;Distal convoluted tubule cells: 3.2;Ependymal cells: 8.7;Microglia: 23.1;Oligodendrocyte progenitor cells: 8.4;Oligodendrocytes: 10.5;Other brain neurons: 4.8;Papillary tip epithelial cells: 4.0;Podocytes: 5.9;Renal collecting duct intercalated cells: 3.2;Renal collecting duct principal cells: 3.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 9.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051671, HPA053556" Enhanced Approved "Nucleoli fibrillar center" NA NA "Cluster 70: Non-specific - Protein processing" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" "Nucleoli fibrillar center" "HPA051671: , HPA053556: " "unprognostic (7.18e-2)" "unprognostic (8.92e-2)" "unprognostic (2.75e-1)" "unprognostic (2.14e-2)" "unprognostic (1.74e-2)" "unprognostic (3.73e-2)" "unprognostic (1.24e-2)" "unprognostic (5.87e-2)" "unprognostic (1.82e-1)" "unprognostic (9.03e-2)" "unprognostic (1.74e-1)" "unprognostic (5.52e-2)" "unprognostic (1.26e-2)" "unprognostic (1.08e-1)" "unprognostic (4.95e-1)" "unprognostic (3.51e-2)" "unprognostic (1.83e-3)" "unprognostic (7.32e-2)" "unprognostic (5.03e-2)" "unprognostic (1.16e-1)" "unprognostic (3.75e-1)" LEO1 ENSG00000166477 "LEO1 homolog, Paf1/RNA polymerase II complex component" Q8WVC0 15 51938025-51971778 "Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epicardial cells: 236.5;Mast cells: 244.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Macrophages, Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040741, HPA040941" Enhanced Enhanced "Nucleoplasm,Nucleoli fibrillar center,Centrosome" No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 76: Non-specific - Metabolism" "Cluster 16: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 58: Mast cells - Allergic inflammatory responses" 43 "Nucleoplasm, Nucleoli fibrillar center" Centrosome "HPA040741: , HPA040941: " "unprognostic (1.33e-1)" "unprognostic (8.34e-2)" "unprognostic (6.04e-2)" "unprognostic (1.93e-2)" "unprognostic (1.79e-1)" "unprognostic (3.10e-2)" "unprognostic (9.10e-2)" "unprognostic (4.39e-3)" "unprognostic (3.64e-2)" "unprognostic (2.60e-2)" "validated prognostic favorable (2.23e-6)" "validated prognostic favorable (2.84e-4)" "unprognostic (1.85e-1)" "unprognostic (4.41e-3)" "unprognostic (8.68e-3)" "unprognostic (1.20e-2)" "unprognostic (2.38e-3)" "unprognostic (1.86e-1)" "unprognostic (2.68e-1)" "unprognostic (1.49e-1)" "unprognostic (1.42e-1)" "unprognostic (3.27e-1)" "unprognostic (8.50e-2)" "unprognostic (2.19e-2)" "unprognostic (1.69e-1)" "unprognostic (5.44e-2)" "unprognostic (3.83e-3)" "unprognostic (1.50e-1)" "unprognostic (1.93e-1)" "unprognostic (1.41e-1)" "unprognostic (1.01e-1)" LEP "OB, OBS" ENSG00000174697 Leptin P41159 7 128241278-128257629 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes, Diabetes mellitus, Disease variant, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 16 "adipose tissue: 288.5;breast: 88.4" "Group enriched" "Detected in some" 5 "Extravillous trophoblasts: 187.9;Syncytiotrophoblasts: 582.7" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Breast Invasive Carcinoma (TCGA): 2.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 17 "testis cancer: 2.4" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Minor Salivary Gland - Adipocytes (Minor salivary gland), Skin - Adipocytes (Skin), Spleen - Smooth muscle cells, Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" "CAB010490, HPA068565" Approved Approved "Vesicles,Plasma membrane" "Secreted to blood" "No annotated function" NA NA 17000000 3800000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 48: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." 8 "Vesicles, Plasma membrane" "CAB010490: , HPA068565: " "unprognostic (1.07e-1)" "unprognostic (3.17e-2)" "unprognostic (1.86e-2)" "unprognostic (1.23e-1)" LEPR "CD295, OBR" ENSG00000116678 "Leptin receptor" P48357 1 65420652-65641559 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins" Receptor "Cancer-related genes, FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "liver: 121.9" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 174.1;Fibro-adipogenic progenitors: 188.5;Fibroblasts: 237.9;Gastric chief cells: 252.3;Hepatocytes: 226.1;Parietal cells: 139.7;Podocytes: 204.7;Vascular endothelial cells: 189.8" "Group enriched" "Detected in all" 4 "choroid plexus epithelial cell: 132.0;endothelial cell: 493.1;fibroblast: 492.0" "Cancer enriched" "Detected in many" 5 "Liver Hepatocellular Carcinoma (TCGA): 39.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 5.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 5.0" "Low cancer specificity" "Detected in all" "Prostate - Endothelial cells, Stomach - Chief cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA030899 Approved Supported Approved "Vesicles,Plasma membrane,Primary cilium,Basal body,Cytosol" "Intracellular and membrane" Receptor NA NA 3300000 "Cluster 33: Non-specific - ATP binding" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 36: Choroid plexus - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 108: Fibroblasts - ECM organization" 7 Vesicles "Plasma membrane, Primary cilium, Basal body, Cytosol" "HPA030899: " "unprognostic (4.19e-1)" "unprognostic (4.96e-2)" "unprognostic (1.36e-1)" "unprognostic (1.50e-3)" "unprognostic (1.17e-2)" "unprognostic (4.71e-2)" "unprognostic (2.98e-1)" "unprognostic (1.97e-2)" "unprognostic (1.83e-1)" "unprognostic (5.06e-2)" "potential prognostic favorable (5.17e-7)" "unprognostic (3.92e-3)" "unprognostic (1.75e-1)" "unprognostic (2.26e-1)" "unprognostic (3.74e-2)" "unprognostic (1.92e-2)" "unprognostic (2.10e-1)" "unprognostic (4.85e-2)" "unprognostic (4.63e-1)" "unprognostic (1.54e-2)" "unprognostic (2.57e-2)" "unprognostic (2.16e-1)" "unprognostic (1.76e-1)" "unprognostic (1.14e-1)" "unprognostic (2.05e-1)" "unprognostic (1.66e-1)" "unprognostic (7.42e-2)" "unprognostic (3.69e-1)" "unprognostic (3.10e-2)" "unprognostic (4.15e-2)" LEPROT "FLJ90360, OB-RGRP, OBRGRP, VPS55" ENSG00000213625 "Leptin receptor overlapping transcript" O15243 1 65420587-65436007 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 12.1;Gastric chief cells: 10.9;Platelets: 22.6" "Cell type enhanced" "Detected in some" "pericyte: 2.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069444 Approved Centrosome NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 15: Kidney cancer - Membrane components" "Cluster 47: Platelets - Hemostasis" 11 Centrosome "HPA069444: " "unprognostic (1.03e-1)" "unprognostic (4.34e-1)" "unprognostic (3.70e-1)" "potential prognostic unfavorable (1.47e-4)" "unprognostic (1.07e-1)" "unprognostic (7.34e-2)" "unprognostic (6.59e-2)" "potential prognostic unfavorable (7.28e-4)" "unprognostic (6.36e-2)" "unprognostic (5.96e-3)" "potential prognostic favorable (9.63e-7)" "unprognostic (2.79e-3)" "unprognostic (7.14e-2)" "unprognostic (2.66e-2)" "unprognostic (5.02e-2)" "unprognostic (1.27e-1)" "unprognostic (1.04e-1)" "unprognostic (6.70e-3)" "unprognostic (4.80e-2)" "unprognostic (5.17e-2)" "potential prognostic unfavorable (6.31e-5)" "unprognostic (1.03e-2)" "unprognostic (2.89e-1)" "unprognostic (1.13e-1)" "unprognostic (1.90e-2)" "unprognostic (4.18e-3)" "unprognostic (1.82e-2)" "unprognostic (3.00e-3)" "unprognostic (1.05e-1)" "unprognostic (2.10e-1)" "unprognostic (1.63e-1)" LEPROTL1 "my047, Vps55" ENSG00000104660 "Leptin receptor overlapping transcript like 1" O95214 8 30095408-30177208 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric progenitor cells: 296.1;Innate lymphoid cells: 242.2;Late primary spermatocytes: 257.7;NK-cells: 268.0;T-cells: 517.6" "Cell type enhanced" "Detected in all" "leukocyte: 162.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047911 Uncertain NA NA "Cluster 11: T-cells - Unknown function" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 31: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 9: T-cells - Adaptive immunity: Regulation" 68 "HPA047911: " "unprognostic (1.63e-1)" "unprognostic (2.72e-2)" "unprognostic (4.81e-1)" "unprognostic (1.02e-1)" "potential prognostic favorable (3.28e-4)" "unprognostic (4.50e-2)" "unprognostic (4.80e-1)" "unprognostic (1.13e-2)" "unprognostic (7.95e-2)" "unprognostic (4.63e-2)" "validated prognostic favorable (2.94e-7)" "validated prognostic favorable (1.40e-4)" "unprognostic (5.42e-2)" "potential prognostic unfavorable (3.61e-4)" "unprognostic (1.73e-1)" "unprognostic (1.92e-1)" "unprognostic (1.48e-1)" "unprognostic (1.14e-1)" "unprognostic (1.44e-1)" "unprognostic (9.29e-2)" "unprognostic (2.46e-2)" "unprognostic (7.51e-2)" "unprognostic (1.75e-1)" "unprognostic (5.63e-3)" "unprognostic (1.00e-2)" "unprognostic (1.27e-1)" "unprognostic (2.74e-1)" "unprognostic (2.45e-1)" "unprognostic (7.44e-2)" "unprognostic (3.55e-1)" "unprognostic (1.38e-1)" LETM1 "Mdm38, SLC55A1." ENSG00000168924 "Leucine zipper and EF-hand containing transmembrane protein 1" O95202 4 1811479-1856156 "Essential proteins, Human disease related genes, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Potassium transport, Transport" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 103.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011029, HPA011100" Supported Supported Mitochondria NA NA 6800 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 40 Mitochondria "HPA011029: , HPA011100: " "unprognostic (2.23e-1)" "unprognostic (3.44e-2)" "unprognostic (2.54e-1)" "unprognostic (5.40e-2)" "potential prognostic favorable (5.62e-4)" "unprognostic (1.73e-1)" "unprognostic (1.97e-1)" "unprognostic (8.98e-3)" "unprognostic (1.69e-1)" "unprognostic (2.05e-3)" "unprognostic (2.75e-2)" "unprognostic (1.71e-2)" "potential prognostic favorable (7.47e-5)" "potential prognostic unfavorable (3.78e-4)" "unprognostic (3.36e-3)" "unprognostic (7.72e-3)" "unprognostic (2.42e-2)" "unprognostic (3.02e-2)" "potential prognostic favorable (9.82e-4)" "unprognostic (1.93e-1)" "unprognostic (1.46e-3)" "unprognostic (1.81e-1)" "unprognostic (2.75e-2)" "unprognostic (3.20e-3)" "unprognostic (1.96e-1)" "unprognostic (2.19e-1)" "unprognostic (1.06e-1)" "unprognostic (1.25e-2)" "unprognostic (5.39e-2)" "unprognostic (5.11e-2)" "unprognostic (1.41e-2)" LETM2 "FLJ25409, SLC55A2" ENSG00000165046 "Leucine zipper and EF-hand containing transmembrane protein 2" Q2VYF4 8 38386207-38409527 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 13.7;testis: 22.2" "Cell type enhanced" "Detected in many" "Early spermatids: 50.4;Epicardial cells: 175.1;Late primary spermatocytes: 131.6;Late spermatids: 75.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 21.7" "Lineage enriched" "Detected in all" 4 "granulocytes: 21.7" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebellum: 32.2" HPA025032 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" Yes No "Cluster 21: Neutrophils - Unknown function" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 72: Neuronal - Signal transduction" "Cluster 20: Non-specific - Transcription regulation" Nucleoplasm "Nuclear bodies, Cytosol" "HPA025032: " "unprognostic (6.36e-2)" "unprognostic (2.00e-1)" "unprognostic (6.90e-2)" "unprognostic (2.20e-2)" "unprognostic (2.08e-1)" "unprognostic (6.13e-3)" "potential prognostic unfavorable (7.45e-5)" "unprognostic (3.58e-1)" "unprognostic (4.73e-2)" "unprognostic (8.62e-3)" "unprognostic (1.20e-2)" "unprognostic (3.29e-1)" "unprognostic (9.53e-2)" "unprognostic (5.35e-1)" "potential prognostic unfavorable (2.21e-5)" "unprognostic (2.49e-2)" "unprognostic (1.10e-2)" "unprognostic (4.09e-1)" "unprognostic (4.13e-2)" "unprognostic (2.20e-1)" "potential prognostic unfavorable (7.97e-5)" "unprognostic (1.85e-2)" "unprognostic (7.77e-2)" "unprognostic (1.45e-1)" "unprognostic (1.24e-2)" "unprognostic (2.62e-1)" "unprognostic (1.11e-2)" "unprognostic (2.59e-1)" "unprognostic (2.27e-2)" "unprognostic (8.57e-2)" LETMD1 "HCCR, HCCR-1, HCCR-2, HCCR1, HCCR2, SLC55A3" ENSG00000050426 "LETM1 domain containing 1" Q6P1Q0 12 51047962-51060424 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074361 Supported Nucleoplasm,Nucleoli,Mitochondria NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 70: Non-specific - Protein processing" "Cluster 23: Choroid plexus - Mixed function" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 12 Mitochondria "Nucleoplasm, Nucleoli" "HPA074361: " "unprognostic (1.92e-2)" "unprognostic (5.43e-2)" "unprognostic (1.57e-2)" "unprognostic (1.08e-2)" "unprognostic (1.46e-2)" "unprognostic (2.83e-1)" "unprognostic (2.10e-3)" "unprognostic (6.07e-2)" "unprognostic (1.00e-2)" "unprognostic (4.14e-2)" "validated prognostic favorable (4.61e-10)" "validated prognostic favorable (2.84e-4)" "unprognostic (3.09e-1)" "unprognostic (5.75e-3)" "unprognostic (4.23e-2)" "unprognostic (2.30e-1)" "unprognostic (1.03e-1)" "unprognostic (1.14e-2)" "unprognostic (7.68e-2)" "unprognostic (2.81e-2)" "unprognostic (2.15e-1)" "unprognostic (3.19e-1)" "unprognostic (4.40e-3)" "unprognostic (7.23e-2)" "potential prognostic favorable (1.51e-4)" "unprognostic (5.87e-2)" "unprognostic (7.36e-2)" "unprognostic (1.09e-1)" "unprognostic (3.21e-1)" "unprognostic (1.95e-1)" "unprognostic (2.84e-2)" LEUTX ENSG00000213921 "Leucine twenty homeobox" A8MZ59 19 39776595-39786291 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA041498 Uncertain Approved Nucleoplasm,Nucleoli NA NA "Cluster 15: Kidney cancer - Membrane components" 37 "Nucleoplasm, Nucleoli" "HPA041498: " LEXM "C1orf177, FLJ40201, LEM" ENSG00000162398 "Lymphocyte expansion molecule" Q3ZCV2 1 54806063-54842252 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 11.9;testis: 4.5;vagina: 4.1" "Cell type enriched" "Detected in some" 4 "Esophageal apical cells: 246.6" "Cell type enhanced" "Detected in some" "eccentric medium spiny neuron: 5.9;leukocyte: 6.1;medium spiny neuron: 10.3" "Cancer enhanced" "Detected in single" "Head and Neck Squamous Cell Carcinoma (TCGA): 1.0" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "gdT-cell: 3.7" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA035889, HPA035890" Uncertain NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 33: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 84: Apical squamous epithelium - Cornification" "HPA035889: , HPA035890: " "unprognostic (2.85e-2)" LFNG SCDO3 ENSG00000106003 "LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase" Q8NES3 7 2512529-2529177 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Developmental protein, Glycosyltransferase, Transferase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 71.9;skin 1: 54.9" "Cell type enhanced" "Detected in many" "Astrocytes: 46.2;Basal prostatic cells: 34.9;Bergmann glia: 51.7;Breast myoepithelial cells: 34.4;cDC: 41.3;Goblet cells: 36.8;Mast cells: 32.6;monocytes: 79.2;Müller glia: 39.6;Neuroendocrine cells: 40.0;NK-cells: 32.5;Pancreatic acinar cells: 29.7" "Group enriched" "Detected in many" 6 "astrocyte: 57.6;Bergmann glia: 64.1;endothelial cell: 23.9;fibroblast: 24.0;leukocyte: 55.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Kidney cancer: 108.5" "Kidney - Fibroblasts, Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069130 Approved Approved "Nuclear membrane,Golgi apparatus" "Intracellular and membrane" "Developmental protein" NA NA 390000 "Cluster 25: Non-specific - Unknown function" "Cluster 8: Pancreas - Proteolysis" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" "Nuclear membrane, Golgi apparatus" "HPA069130: " "unprognostic (1.44e-1)" "unprognostic (5.03e-2)" "unprognostic (3.60e-1)" "unprognostic (2.46e-2)" "unprognostic (9.35e-2)" "unprognostic (1.30e-1)" "unprognostic (4.95e-2)" "unprognostic (1.31e-3)" "unprognostic (3.03e-2)" "unprognostic (1.12e-1)" "unprognostic (2.71e-1)" "unprognostic (9.94e-2)" "unprognostic (1.06e-2)" "unprognostic (4.01e-1)" "unprognostic (1.39e-1)" "unprognostic (6.51e-2)" "unprognostic (1.75e-1)" "unprognostic (2.16e-1)" "unprognostic (4.83e-2)" "unprognostic (2.11e-1)" "unprognostic (2.65e-1)" "unprognostic (2.43e-2)" "unprognostic (7.23e-2)" "unprognostic (1.56e-1)" "unprognostic (5.45e-2)" "unprognostic (5.30e-2)" "unprognostic (8.44e-2)" "unprognostic (5.91e-2)" "unprognostic (4.19e-1)" "unprognostic (7.72e-2)" "unprognostic (2.98e-1)" LGALS1 GBP ENSG00000100097 "Galectin 1" P09382 22 37675636-37679802 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "cDC: 1781.1;Decidual stromal cells: 10329.3;Endometrial stromal cells: 2107.5;Extravillous trophoblasts: 2291.6;Fibroblasts: 1910.9;Hepatic stellate cells: 6725.9;Hofbauer cells: 2831.6;Melanocytes: 1948.2;Monocyte progenitors: 1860.1;monocytes: 1613.0;Ovarian stromal cells: 2597.2;Pericytes: 1746.4;Schwann cells: 1920.5;Smooth muscle cells: 3074.6" "Cell type enhanced" "Detected in all" "pericyte: 504.3;vascular associated smooth muscle cell: 383.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast), Spleen - Fibroblasts_1, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 2024.9" "HPA000646, HPA001130, CAB002157" Enhanced Supported Cytosol "Secreted to blood" Other No Yes 10000000 14000000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 74: Non-specific - Signal transduction" "Cluster 45: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 108: Fibroblasts - ECM organization" 89 Cytosol "CAB002157: , HPA000646: , HPA001130: " "unprognostic (1.12e-1)" "unprognostic (2.71e-1)" "unprognostic (2.12e-2)" "unprognostic (1.54e-1)" "unprognostic (7.12e-3)" "unprognostic (3.54e-1)" "unprognostic (3.36e-2)" "potential prognostic unfavorable (4.50e-4)" "unprognostic (1.62e-3)" "unprognostic (1.92e-2)" "validated prognostic unfavorable (3.26e-5)" "validated prognostic unfavorable (1.96e-5)" "unprognostic (1.61e-3)" "potential prognostic unfavorable (3.67e-5)" "unprognostic (7.00e-2)" "unprognostic (3.26e-2)" "potential prognostic unfavorable (8.27e-4)" "unprognostic (6.60e-2)" "unprognostic (3.39e-2)" "unprognostic (6.79e-2)" "unprognostic (3.02e-1)" "unprognostic (8.21e-3)" "unprognostic (2.25e-1)" "unprognostic (2.55e-1)" "unprognostic (2.48e-1)" "unprognostic (1.30e-3)" "potential prognostic favorable (4.92e-4)" "unprognostic (8.22e-3)" "unprognostic (8.92e-3)" "unprognostic (8.92e-2)" "unprognostic (1.10e-1)" LGALS12 GRIP1 ENSG00000133317 "Galectin 12" Q96DT0 11 63506052-63516774 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 73.5;breast: 39.7" "Group enriched" "Detected in some" 5 "Adipocytes: 152.6;Platelets: 243.0" "Cell type enhanced" "Detected in single" "choroid plexus epithelial cell: 1.2" "Cancer enhanced" "Detected in some" "Kidney Renal Clear Cell Carcinoma (TCGA): 4.7" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 20 "eosinophil: 556.2" "Lineage enriched" "Detected in many" 20 "granulocytes: 556.2" "Group enriched" "Detected in some" 8 "Leukemia: 16.6;Rhabdoid: 7.6" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Minor Salivary Gland - Adipocytes (Minor salivary gland), Skin - Adipocytes (Skin), Spleen - Neutrophils_1" "Not detected" "Not detected" "Not detected" "Not detected" HPA021124 Approved Cytosol NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 89: Adipocytes - Lipid metabolism" Cytosol "HPA021124: " "unprognostic (1.44e-1)" "unprognostic (1.07e-2)" "potential prognostic unfavorable (7.61e-4)" "unprognostic (3.94e-1)" "unprognostic (3.08e-1)" "unprognostic (3.70e-3)" "unprognostic (1.85e-1)" "unprognostic (1.17e-1)" LGALS13 "PLAC8, PP13" ENSG00000105198 "Galectin 13" Q9UHV8 19 39602524-39607474 "Predicted intracellular proteins" Apoptosis Hemagglutinin "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 32 "placenta: 10.6" "Cell type enriched" "Detected in some" 19 "Syncytiotrophoblasts: 590.0" "Group enriched" "Detected in some" 5 "cerebellar inhibitory: 10.9;mammillary body: 5.3" "Cancer enriched" "Detected in single" 6 "Thyroid Carcinoma (TCGA): 1.3" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 13 "testis cancer: 1.9" "Testis - Late spermatids" HPA046803 Supported Nucleoplasm NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 70: DU4475 - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 4 Nucleoplasm "HPA046803: " "unprognostic (2.06e-1)" LGALS14 "CLC2, PPL13" ENSG00000006659 "Galectin 14" Q8TCE9 19 39704481-39709444 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 65 "placenta: 61.7" "Cell type enriched" "Detected in some" 6 "Syncytiotrophoblasts: 100.4" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 12 "Liver Hepatocellular Carcinoma (TCGA): 13.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 4.5;Uterine cancer: 5.4" HPA065180 Supported Nucleoplasm NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 48: Non-specific - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." 43 Nucleoplasm "HPA065180: " "unprognostic (2.46e-1)" "unprognostic (9.51e-2)" "unprognostic (5.15e-2)" "unprognostic (2.07e-1)" "unprognostic (3.11e-1)" LGALS16 ENSG00000249861 "Galectin 16" A8MUM7 19 39655913-39660647 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 14 "placenta: 5.4" "Cell type enriched" "Detected in some" 120 "Syncytiotrophoblasts: 1836.8" "Group enriched" "Detected in some" 5 "cerebellar inhibitory: 5.5;mammillary body: 2.4" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 24 "testis cancer: 10.9" NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 34: Testis cancer - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" LGALS2 HL14 ENSG00000100079 "Galectin 2" P05162 22 37570248-37582616 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 315.1;intestine: 186.3;kidney: 142.2;pancreas: 199.3" "Cell type enhanced" "Detected in many" "cDC: 636.9;Cholangiocytes: 577.7;Colonocytes: 755.0;Enteric stem cells: 316.8;Enteric transient amplifying cells: 688.6;Enterocytes: 2372.2;Epididymal efferent duct absorptive cells: 336.7;Gastric progenitor cells: 398.6;Goblet cells: 310.1;Pancreatic acinar cells: 259.8;Paneth cells: 220.4" "Cell type enhanced" "Detected in single" "leukocyte: 2.4" "Group enriched" "Detected in all" 4 "Kidney Renal Clear Cell Carcinoma (TCGA): 162.6;Kidney Renal Papillary Cell Carcinoma (TCGA): 123.7;Pancreatic Adenocarcinoma (TCGA): 53.8;Stomach Adenocarcinoma (TCGA): 81.0;Testicular Germ Cell Tumor (TCGA): 46.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 27 "classical monocyte: 1470.6;intermediate monocyte: 555.0;myeloid DC: 1211.4" "Group enriched" "Detected in all" 50 "dendritic cells: 1211.4;monocytes: 1470.6" "Cancer enhanced" "Detected in many" "Gastric cancer: 36.8;liver cancer: 20.7" "Adipose visceral - Mesothelial cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Thyroid gland - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA003536, CAB025198" Enhanced Approved Nucleoplasm,Mitochondria NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 60: Stomach - Digestion" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 1: Enterocytes - Absorption and Digestion" 7 Mitochondria Nucleoplasm "CAB025198: , HPA003536: " "unprognostic (2.50e-1)" "unprognostic (6.25e-3)" "unprognostic (5.35e-2)" "unprognostic (4.73e-3)" "unprognostic (1.23e-2)" "unprognostic (4.20e-3)" "unprognostic (1.04e-1)" "unprognostic (6.21e-3)" "unprognostic (1.91e-1)" "validated prognostic favorable (1.85e-10)" "validated prognostic favorable (1.52e-11)" "unprognostic (5.32e-2)" "unprognostic (4.35e-1)" "unprognostic (2.58e-2)" "unprognostic (5.44e-2)" "unprognostic (8.78e-2)" "unprognostic (1.25e-1)" "unprognostic (1.60e-2)" "unprognostic (3.38e-1)" "unprognostic (9.83e-2)" "unprognostic (5.91e-2)" "unprognostic (3.55e-1)" "unprognostic (1.84e-1)" "potential prognostic favorable (4.72e-4)" "unprognostic (1.08e-1)" "unprognostic (2.83e-3)" "unprognostic (3.63e-1)" "unprognostic (1.75e-2)" "unprognostic (6.67e-2)" "unprognostic (2.97e-1)" LGALS3 "GALIG, LGALS2, MAC-2" ENSG00000131981 "Galectin 3" P17931 14 55124110-55145423 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Immunity, Innate immunity, mRNA processing, mRNA splicing" "IgE-binding protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 1118.6" "Cell type enhanced" "Detected in many" "Colonocytes: 6455.8;Decidual stromal cells: 2188.3;Enteric transient amplifying cells: 2414.7;Enterocytes: 4003.9;Esophageal apical cells: 3989.9;Ocular epithelial cells: 1947.0;Salivary duct cells: 1971.6" "Cell type enhanced" "Detected in many" "Bergmann glia: 129.2;endothelial cell: 145.4;fibroblast: 89.4;vascular associated smooth muscle cell: 69.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 652.7;intermediate monocyte: 545.4;myeloid DC: 398.3;non-classical monocyte: 443.7;T-reg: 252.7" "Group enriched" "Detected in all" 13 "dendritic cells: 398.3;monocytes: 652.7;T-cells: 252.7" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA003162, CAB005191, HPA076528" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" Immunity NA NA 1800000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 77: Intestine - Digestion" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 86 "Nucleoplasm, Cytosol" "Plasma membrane" "CAB005191: , HPA003162: , HPA076528: " "unprognostic (7.29e-2)" "unprognostic (2.02e-1)" "unprognostic (9.10e-2)" "unprognostic (1.73e-1)" "unprognostic (5.97e-2)" "unprognostic (4.11e-2)" "unprognostic (5.90e-3)" "potential prognostic unfavorable (2.47e-6)" "unprognostic (1.27e-1)" "unprognostic (5.26e-2)" "unprognostic (4.83e-3)" "unprognostic (1.34e-1)" "unprognostic (4.38e-1)" "unprognostic (1.26e-3)" "unprognostic (1.09e-1)" "unprognostic (2.27e-3)" "unprognostic (2.76e-2)" "unprognostic (3.24e-3)" "unprognostic (5.62e-2)" "unprognostic (1.39e-1)" "unprognostic (1.67e-1)" "unprognostic (1.08e-3)" "unprognostic (1.88e-1)" "unprognostic (3.62e-2)" "unprognostic (1.20e-1)" "unprognostic (1.34e-2)" "unprognostic (9.73e-2)" "unprognostic (9.17e-2)" "unprognostic (1.24e-2)" "unprognostic (3.36e-3)" "unprognostic (1.16e-1)" LGALS3BP "90K, BTBD17B, CyCAP, gp90, M2BP, MAC-2-BP, TANGO10B" ENSG00000108679 "Galectin 3 binding protein" Q08380 17 78971238-78979947 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 509.9;Decidual stromal cells: 897.4;Enterocytes: 863.4;Extravillous trophoblasts: 552.5;Foveolar cells: 490.9" "Cell type enhanced" "Detected in many" "pericyte: 87.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 5 "monocytes: 27.2;T-cells: 68.6" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Kidney - Fibroblasts, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Thyrotropes, Skeletal muscle - Fibroblasts, Skin - Fibroblasts_1, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000410, HPA000554" Uncertain "Secreted to blood" "Cell adhesion" NA NA 2700000000 "Cluster 11: T-cells - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 94: Gonadal somatic cells - Mixed function" 58 "HPA000410: , HPA000554: " "unprognostic (2.31e-1)" "unprognostic (4.56e-2)" "unprognostic (1.18e-1)" "unprognostic (3.38e-2)" "unprognostic (6.75e-2)" "unprognostic (9.24e-2)" "unprognostic (6.03e-2)" "unprognostic (2.17e-3)" "unprognostic (7.76e-3)" "unprognostic (1.96e-1)" "validated prognostic unfavorable (1.67e-4)" "validated prognostic unfavorable (2.64e-4)" "unprognostic (2.65e-2)" "unprognostic (6.71e-3)" "unprognostic (7.13e-2)" "unprognostic (1.39e-1)" "unprognostic (1.82e-1)" "unprognostic (1.93e-2)" "unprognostic (1.59e-1)" "unprognostic (6.80e-2)" "unprognostic (1.68e-2)" "unprognostic (4.77e-1)" "unprognostic (1.87e-1)" "unprognostic (2.61e-1)" "unprognostic (4.93e-1)" "unprognostic (2.35e-1)" "unprognostic (5.25e-3)" "unprognostic (1.73e-1)" "unprognostic (2.87e-2)" "unprognostic (1.96e-1)" "unprognostic (1.76e-3)" LGALS4 GAL4 ENSG00000171747 "Galectin 4" P56470 19 38801671-38812945 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "intestine: 1827.2" "Cell type enhanced" "Detected in some" "Colonocytes: 5486.9;Enteric stem cells: 2114.9;Enteric transient amplifying cells: 3292.5;Enterocytes: 3038.9;Gastric progenitor cells: 693.4;Goblet cells: 3764.1;Paneth cells: 974.6" "Low cell type specificity" "Detected in some" "Group enriched" "Detected in many" 12 "Colon Adenocarcinoma (TCGA): 732.3;Liver Hepatocellular Carcinoma (TCGA): 204.3;Pancreatic Adenocarcinoma (TCGA): 387.9;Rectum Adenocarcinoma (TCGA): 664.1;Stomach Adenocarcinoma (TCGA): 317.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 304.6;Gastric cancer: 203.9" "Colon - Colon enterocytes, Prostate - Urothelial cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in some" "Not detected" "Not detected" "CAB025653, HPA031184, HPA031185, HPA031186" Enhanced Uncertain "Plasma membrane" NA NA 110000 "Cluster 77: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 97: Non-specific - Cellular respiration" 7 "Plasma membrane" "CAB025653: , HPA031184: , HPA031185: , HPA031186: " "unprognostic (3.48e-2)" "unprognostic (1.33e-1)" "unprognostic (2.00e-1)" "unprognostic (7.38e-3)" "unprognostic (1.07e-2)" "unprognostic (1.60e-1)" "unprognostic (1.66e-1)" "unprognostic (2.20e-2)" "unprognostic (1.69e-2)" "unprognostic (3.82e-2)" "unprognostic (9.91e-2)" "unprognostic (9.45e-2)" "unprognostic (3.42e-2)" "unprognostic (7.13e-2)" "unprognostic (5.55e-2)" "unprognostic (2.38e-2)" "unprognostic (8.40e-2)" "unprognostic (1.46e-1)" "unprognostic (2.39e-3)" LGALS7 "GAL7, LGALS7A, PIG1, TP53I1" ENSG00000205076 "Galectin 7" P47929 19 38770968-38773517 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 331.6;esophagus: 613.2;skin 1: 1404.3" "Group enriched" "Detected in some" 5 "Basal keratinocytes: 272.9;Esophageal apical cells: 212.3;Esophageal basal cells: 296.1;Esophageal suprabasal cells: 686.6;Suprabasal keratinocytes: 685.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 382.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "Esophageal cancer: 12.5;head and neck cancer: 28.3" "HPA001549, CAB032606" Enhanced "Intracellular and membrane" Other NA NA 5800000 "Cluster 58: Skin - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 34 "CAB032606: , HPA001549: " "unprognostic (2.39e-3)" "unprognostic (2.78e-2)" "unprognostic (2.35e-1)" "unprognostic (3.09e-3)" "unprognostic (1.31e-1)" "unprognostic (2.28e-2)" "unprognostic (1.34e-1)" "unprognostic (2.90e-1)" "unprognostic (1.55e-1)" "unprognostic (1.14e-1)" "unprognostic (5.37e-2)" "unprognostic (4.12e-1)" "unprognostic (1.76e-1)" "unprognostic (3.22e-1)" "unprognostic (1.92e-1)" "unprognostic (3.66e-2)" "unprognostic (2.99e-2)" LGALS7B GAL7 ENSG00000178934 "Galectin 7B" P47929 19 38789200-38791754 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 5653.1" "Cell type enriched" "Detected in some" 4 "Suprabasal keratinocytes: 1307.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 477.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 5.3;head and neck cancer: 2.3;liver cancer: 1.9" "Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Urothelial cells, Skin - Keratinocyte (other)" "HPA001549, CAB025100" Supported "Intracellular and membrane" Other NA NA 5800000 "Cluster 9: Skin - Hair follicle development" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 26: Keratinocytes - Keratinization" 35 "CAB025100: , HPA001549: " "unprognostic (6.56e-3)" "unprognostic (2.77e-2)" "unprognostic (2.66e-2)" "unprognostic (6.90e-2)" "unprognostic (5.55e-2)" "unprognostic (1.95e-1)" "unprognostic (2.67e-1)" "unprognostic (3.23e-1)" "unprognostic (3.28e-1)" "unprognostic (2.03e-2)" "unprognostic (2.68e-2)" "unprognostic (2.80e-2)" "unprognostic (3.94e-1)" "unprognostic (1.26e-1)" "unprognostic (5.11e-2)" "unprognostic (2.38e-1)" "unprognostic (2.84e-3)" LGALS8 PCTA-1 ENSG00000116977 "Galectin 8" O00214 1 236518000-236552981 "Predicted intracellular proteins" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 319.2;Kupffer cells: 186.5;Late primary spermatocytes: 269.1;Late spermatids: 345.0;Platelets: 187.8;Syncytiotrophoblasts: 235.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 119.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Skeletal muscle - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012734, HPA030491" Approved Approved "Plasma membrane" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 35: Non-specific - Mixed function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 22 "Plasma membrane" "HPA012734: , HPA030491: " "unprognostic (1.60e-1)" "unprognostic (2.05e-2)" "unprognostic (2.77e-1)" "unprognostic (1.13e-1)" "unprognostic (5.12e-2)" "potential prognostic unfavorable (5.24e-4)" "unprognostic (7.34e-3)" "potential prognostic unfavorable (2.37e-5)" "unprognostic (1.46e-2)" "unprognostic (4.22e-2)" "unprognostic (2.05e-3)" "unprognostic (8.71e-2)" "unprognostic (3.56e-2)" "unprognostic (4.37e-1)" "unprognostic (5.23e-2)" "unprognostic (4.94e-2)" "unprognostic (2.60e-1)" "unprognostic (3.12e-1)" "unprognostic (1.61e-1)" "unprognostic (3.41e-2)" "unprognostic (3.04e-2)" "unprognostic (1.09e-2)" "unprognostic (1.69e-1)" "unprognostic (5.72e-3)" "unprognostic (4.03e-2)" "unprognostic (2.62e-2)" "unprognostic (2.32e-2)" "unprognostic (3.02e-1)" "unprognostic (1.73e-1)" "unprognostic (2.45e-1)" "unprognostic (3.16e-1)" LGALS9 LGALS9A ENSG00000168961 "Galectin 9" O00182 17 27629798-27649560 "Essential proteins, Predicted intracellular proteins, Predicted secreted proteins" "Chemotaxis, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 92.9;stomach 1: 82.6" "Cell type enhanced" "Detected in many" "cDC: 91.8;Colonocytes: 184.1;Enteric stem cells: 115.9;Enteric transient amplifying cells: 108.6;Erythrocyte progenitors: 100.8;Foveolar cells: 157.9;Goblet cells: 181.3;Hofbauer cells: 310.2;Kupffer cells: 313.6;Macrophages: 127.5;monocytes: 157.7;Parietal cells: 99.0" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 90.1;endothelial cell: 25.1;leukocyte: 20.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 66.9" "Adrenal gland - Macrophages, Lung - Macrophages, Spleen - Macrophages, Stomach - Gastric mucous cells" "HPA046876, HPA047218, CAB080347" Approved Supported Cytosol "Secreted to blood" Immunity NA NA 448000 16000 "Cluster 25: Non-specific - Unknown function" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 64 Cytosol "CAB080347: , HPA046876: , HPA047218: " "unprognostic (1.17e-2)" "unprognostic (4.40e-2)" "unprognostic (5.77e-2)" "unprognostic (8.60e-3)" "unprognostic (1.21e-1)" "unprognostic (3.02e-2)" "unprognostic (1.35e-1)" "unprognostic (1.89e-1)" "unprognostic (1.03e-2)" "unprognostic (6.96e-2)" "unprognostic (5.54e-2)" "unprognostic (4.19e-1)" "unprognostic (3.09e-1)" "unprognostic (5.03e-3)" "unprognostic (6.97e-2)" "unprognostic (3.09e-1)" "unprognostic (7.12e-3)" "unprognostic (1.89e-1)" "unprognostic (1.09e-1)" "unprognostic (1.84e-1)" "unprognostic (3.81e-2)" "unprognostic (3.09e-3)" "unprognostic (1.16e-1)" "unprognostic (7.92e-2)" "unprognostic (4.42e-2)" "unprognostic (1.06e-1)" "unprognostic (9.87e-2)" "unprognostic (4.90e-2)" "unprognostic (6.16e-3)" "unprognostic (4.18e-2)" "unprognostic (1.55e-1)" LGALS9B ENSG00000170298 "Galectin 9B" Q3B8N2 17 20449395-20467539 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 14.6;intestine: 10.4;stomach 1: 29.1" "Group enriched" "Detected in some" 4 "Foveolar cells: 220.2;Goblet cells: 67.7" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rectum Adenocarcinoma (TCGA): 7.1" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 17 "NK-cell: 13.3" "Lineage enriched" "Detected in single" 17 "NK-cells: 13.3" "Cancer enhanced" "Detected in some" "head and neck cancer: 3.3;pancreatic cancer: 2.4" "Colon - Colon enterocytes, Stomach - Gastric mucous cells" "HPA046876, HPA047218" Approved Uncertain Cytosol NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 68: Foveolar cells - Mucosal defense" 9 Cytosol "HPA046876: , HPA047218: " "unprognostic (1.22e-1)" "unprognostic (6.65e-2)" "unprognostic (2.72e-2)" "unprognostic (1.02e-1)" "unprognostic (1.01e-1)" "unprognostic (1.70e-2)" "unprognostic (8.56e-2)" "unprognostic (9.14e-3)" "unprognostic (2.10e-3)" "unprognostic (3.58e-2)" "unprognostic (2.54e-1)" "unprognostic (8.38e-3)" LGALS9C ENSG00000171916 "Galectin 9C" Q6DKI2 17 18476737-18494945 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 10.3;intestine: 9.2;stomach 1: 10.8" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "ependymal cell: 1.1;leukocyte: 2.7" "Cancer enhanced" "Detected in some" "Rectum Adenocarcinoma (TCGA): 2.9" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "neutrophil: 1.9;NK-cell: 5.5" "Group enriched" "Detected in many" 6 "granulocytes: 1.9;NK-cells: 5.5" "Not detected" "Not detected" "Colon - Colon enterocytes, Minor Salivary Gland - Minor salivary gland basal cells, Stomach - Gastric mucous cells" "HPA046876, HPA047218" Approved Approved Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 102: Non-specific - Mixed function" 28 Cytosol "HPA046876: , HPA047218: " "potential prognostic favorable (3.67e-4)" "unprognostic (9.56e-2)" "unprognostic (1.02e-1)" "unprognostic (8.92e-3)" "unprognostic (3.50e-2)" "potential prognostic favorable (2.94e-4)" "unprognostic (2.24e-1)" "unprognostic (8.56e-3)" LGALSL "GRP, HSPC159" ENSG00000119862 "Galectin like" Q3ZCW2 2 64453969-64461381 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 83.9;skin 1: 88.4" "Cell type enhanced" "Detected in many" "Megakaryocytes: 630.5;Ocular epithelial cells: 423.9;Platelets: 923.1;Suprabasal keratinocytes: 170.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 1.5;neutrophil: 1.6" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046079 Approved Approved Nucleoplasm NA NA 6400000 "Cluster 20: Non-specific - DNA binding" "Cluster 37: Skin - Keratinization" "Cluster 5: Non-specific - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 100: Stratified epithelial cells - Barrier functions" 7 Nucleoplasm "HPA046079: " "unprognostic (1.67e-1)" "unprognostic (1.14e-1)" "unprognostic (2.39e-1)" "unprognostic (3.53e-3)" "unprognostic (4.08e-1)" "unprognostic (7.99e-2)" "unprognostic (2.17e-2)" "unprognostic (1.57e-1)" "unprognostic (5.20e-2)" "validated prognostic favorable (1.76e-7)" "validated prognostic favorable (4.08e-4)" "potential prognostic favorable (3.37e-5)" "unprognostic (1.11e-3)" "unprognostic (1.70e-1)" "unprognostic (4.45e-2)" "unprognostic (2.12e-1)" "unprognostic (2.45e-3)" "unprognostic (5.95e-3)" "unprognostic (1.94e-1)" "unprognostic (1.08e-1)" "unprognostic (2.22e-1)" "unprognostic (9.63e-3)" "unprognostic (1.71e-1)" "unprognostic (9.72e-3)" "unprognostic (1.20e-1)" "unprognostic (1.16e-1)" "unprognostic (3.13e-2)" "unprognostic (9.71e-2)" "unprognostic (1.53e-2)" LGI1 "EPITEMPIN, EPT, ETL1, IB1099" ENSG00000108231 "Leucine rich glioma inactivated 1" O95970 10 93757840-93806272 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 42.1;choroid plexus: 68.6" "Cell type enhanced" "Detected in some" "Astrocytes: 284.9;Bergmann glia: 95.7;Brain excitatory neurons: 73.3;Brain inhibitory neurons: 90.5;Choroid plexus epithelial cells: 465.5;Ependymal cells: 49.3;Myonuclei: 49.6;Other brain neurons: 87.1;Pituicytes/FSCs: 269.3;Retinal pigment epithelial cells: 157.7" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 441.1" "Group enriched" "Detected in some" 5 "Glioblastoma Multiforme (TCGA): 9.4;Testicular Germ Cell Tumor (TCGA): 2.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 3.0;Rhabdoid: 6.2;testis cancer: 3.1" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal medulla cells, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted in brain" "No annotated function" NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 2 "unprognostic (1.57e-3)" "unprognostic (2.19e-3)" "unprognostic (2.55e-1)" "unprognostic (2.47e-1)" LGI2 "FLJ10675, KIAA1916" ENSG00000153012 "Leucine rich repeat LGI family member 2" Q8N0V4 4 24998847-25030946 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "parathyroid gland: 120.3" "Cell type enhanced" "Detected in some" "Brain inhibitory neurons: 17.7;Hofbauer cells: 8.7;Loop of henle epithelial cells: 22.4;Macrophages: 13.0;Medullary thymic epithelial cells: 7.2;Oligodendrocyte progenitor cells: 10.4;Other brain neurons: 8.2;Retinal ganglion cells: 15.5;Smooth muscle cells: 33.5;Vascular smooth muscle cells: 14.5" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 74.9;MGE interneuron: 49.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Macrophages, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017140 Approved Uncertain Centrosome "Secreted to blood" "No annotated function" NA NA "Cluster 69: Parathyroid gland - Mixed function" "Cluster 30: White matter - Myelination" "Cluster 18: Liver cancer - Metabolism" "Cluster 109: Neurons - Neuronal signaling" Centrosome "HPA017140: " "unprognostic (8.67e-3)" "unprognostic (1.41e-1)" "unprognostic (1.31e-1)" "unprognostic (1.44e-2)" "unprognostic (2.68e-2)" "unprognostic (7.46e-3)" "unprognostic (4.90e-2)" "unprognostic (2.87e-1)" "unprognostic (8.46e-2)" "unprognostic (1.38e-1)" "unprognostic (3.48e-1)" "unprognostic (1.34e-2)" "unprognostic (3.66e-2)" "potential prognostic unfavorable (7.23e-4)" "unprognostic (8.70e-3)" "unprognostic (1.58e-1)" "unprognostic (1.46e-2)" "unprognostic (2.14e-1)" "unprognostic (1.79e-1)" "unprognostic (4.41e-2)" "unprognostic (3.44e-1)" "unprognostic (6.84e-2)" "unprognostic (1.58e-2)" LGI3 ENSG00000168481 "Leucine rich repeat LGI family member 3" Q8N145 8 22146830-22157084 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Exocytosis "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 95.3" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 61.6;Brain excitatory neurons: 14.0;Brain inhibitory neurons: 20.4;Esophageal apical cells: 14.9;Melanocytes: 74.4;Oligodendrocytes: 97.2;Other brain neurons: 14.7" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 91.5;oligodendrocyte: 96.9" "Group enriched" "Detected in many" 5 "Glioblastoma Multiforme (TCGA): 10.0;Skin Cutaneous Melanoma (TCGA): 33.2;Thyroid Carcinoma (TCGA): 8.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 28 "skin cancer: 13.5" "Adipose subcutaneous - Smooth muscle cells, Colon - Colon enteroendocrine cells, Kidney - Proximal tubular cells, Pancreas - Alpha cells, Pancreas - Beta cells, Pituitary gland - Corticotropes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted in brain" Other NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 80: Oligodendrocytes - Myelination" "unprognostic (1.18e-2)" "unprognostic (1.50e-1)" "unprognostic (9.99e-2)" "unprognostic (2.35e-1)" "unprognostic (7.14e-3)" "unprognostic (4.36e-2)" "unprognostic (6.85e-3)" "unprognostic (3.22e-1)" "unprognostic (3.23e-1)" "unprognostic (4.58e-2)" "unprognostic (5.83e-3)" "unprognostic (9.56e-2)" "unprognostic (3.65e-2)" LGI4 ENSG00000153902 "Leucine rich repeat LGI family member 4" Q8N135 19 35124513-35142451 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 125.9;Bergmann glia: 304.7;Cardiomyocytes: 128.0;Hepatic stellate cells: 83.9;Müller glia: 93.7;Pericytes: 203.5;Schwann cells: 722.2;Thymic myoid cells: 96.5;Vascular smooth muscle cells: 98.2" "Cell type enhanced" "Detected in many" "astrocyte: 127.3;Bergmann glia: 299.6" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 48.6;Skin Cutaneous Melanoma (TCGA): 33.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney cancer: 4.4;skin cancer: 3.7" "Breast - Endothelial cells, Colon - Enteric glia cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042116, HPA043556" Approved Approved "Golgi apparatus" "Secreted in brain" "No annotated function" NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 39: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 110: Mural cells - ECM organization" "Golgi apparatus" "HPA042116: , HPA043556: " "unprognostic (1.44e-1)" "unprognostic (2.65e-1)" "unprognostic (8.09e-2)" "potential prognostic favorable (5.43e-4)" "unprognostic (1.45e-1)" "unprognostic (1.05e-1)" "unprognostic (1.11e-2)" "unprognostic (1.51e-1)" "unprognostic (5.07e-2)" "potential prognostic favorable (6.36e-4)" "unprognostic (9.71e-3)" "unprognostic (9.04e-3)" "potential prognostic unfavorable (4.59e-6)" "unprognostic (4.08e-2)" "unprognostic (2.03e-1)" "unprognostic (2.49e-2)" "unprognostic (4.19e-1)" "potential prognostic favorable (8.86e-4)" "unprognostic (5.10e-2)" "unprognostic (1.08e-1)" "unprognostic (2.92e-2)" "unprognostic (1.62e-2)" "unprognostic (3.20e-1)" "unprognostic (7.51e-2)" LGMN "LGMN1, PRSC1" ENSG00000100600 Legumain Q99538 14 92703807-92748679 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 404.3;Hofbauer cells: 2621.1;Kupffer cells: 1060.8;Macrophages: 653.4;Syncytiotrophoblasts: 585.3" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 117.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 11 "plasmacytoid DC: 209.4" "Lineage enriched" "Detected in all" 12 "dendritic cells: 209.4" "Low cancer specificity" "Detected in all" "Adipose visceral - Macrophages, Kidney - Proximal tubular cells, Skeletal muscle - Macrophages, Spleen - Macrophages, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001426 Enhanced Approved Nucleoplasm,Vesicles "Intracellular and membrane" Enzyme NA NA 750000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 12: Non-specific - Vasculature" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 17 Vesicles Nucleoplasm "HPA001426: " "unprognostic (4.20e-1)" "unprognostic (6.53e-2)" "unprognostic (1.67e-1)" "unprognostic (9.76e-2)" "unprognostic (2.19e-1)" "unprognostic (6.04e-3)" "unprognostic (1.15e-1)" "unprognostic (3.50e-2)" "unprognostic (5.84e-2)" "unprognostic (1.31e-1)" "potential prognostic favorable (1.90e-4)" "unprognostic (1.08e-1)" "unprognostic (1.05e-1)" "unprognostic (4.21e-2)" "unprognostic (1.79e-1)" "unprognostic (1.33e-1)" "unprognostic (7.02e-2)" "unprognostic (6.07e-2)" "unprognostic (1.05e-2)" "unprognostic (2.69e-2)" "unprognostic (9.66e-3)" "unprognostic (1.09e-1)" "unprognostic (4.16e-2)" "unprognostic (2.41e-1)" "potential prognostic unfavorable (1.95e-4)" "unprognostic (2.51e-1)" "unprognostic (2.32e-1)" "unprognostic (1.85e-2)" "unprognostic (5.02e-2)" "unprognostic (1.10e-2)" "unprognostic (1.59e-2)" LGR4 GPR48 ENSG00000205213 "Leucine rich repeat containing G protein-coupled receptor 4" Q9BXB1 11 27365961-27472790 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms, Differentiation, Immunity, Innate immunity, Spermatogenesis, Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" Osteoporosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bergmann glia: 588.2;Distal convoluted tubule cells: 1083.9;Endometrial glandular cells: 726.4;Loop of henle epithelial cells: 599.3;Müller glia: 644.6;Pancreatic acinar cells: 671.5;Pituicytes/FSCs: 769.3;Podocytes: 677.0;Renal collecting duct intercalated cells: 992.3;Syncytiotrophoblasts: 615.9" "Cell type enhanced" "Detected in all" "Bergmann glia: 615.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Skin - Outer root sheath cells, Stomach - Gastric mucous cells, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030267, HPA054350" Uncertain Approved "Centriolar satellite,Centrosome,Basal body" NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 44: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 51: Secretory epithelial cells - Mixed function" 20 Centrosome "Centriolar satellite, Basal body" "HPA030267: , HPA054350: " "unprognostic (2.92e-3)" "unprognostic (1.58e-2)" "unprognostic (7.15e-2)" "unprognostic (3.40e-2)" "unprognostic (1.21e-1)" "unprognostic (5.77e-3)" "unprognostic (5.38e-3)" "unprognostic (3.42e-1)" "unprognostic (3.20e-1)" "unprognostic (4.20e-1)" "potential prognostic favorable (3.93e-9)" "unprognostic (2.25e-3)" "unprognostic (2.15e-1)" "unprognostic (1.60e-1)" "unprognostic (1.01e-1)" "unprognostic (1.10e-3)" "unprognostic (7.69e-3)" "unprognostic (4.62e-2)" "unprognostic (2.33e-2)" "unprognostic (1.10e-1)" "unprognostic (3.64e-1)" "unprognostic (6.35e-3)" "unprognostic (9.20e-2)" "unprognostic (2.52e-1)" "unprognostic (1.96e-2)" "unprognostic (5.85e-2)" "unprognostic (3.82e-2)" "unprognostic (4.31e-1)" "unprognostic (5.09e-1)" "unprognostic (6.17e-2)" "unprognostic (2.00e-1)" LGR5 "FEX, GPR49, GPR67, HG38" ENSG00000139292 "Leucine rich repeat containing G protein-coupled receptor 5" O75473 12 71439798-71586310 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 15.9;placenta: 17.9;skeletal muscle: 21.2" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 330.0;Endometrial luminal cells: 280.2;Enteric stem cells: 239.7;Myonuclei: 500.8;Oligodendrocytes: 135.8;Paneth cells: 228.2;Pituicytes/FSCs: 283.4" "Cell type enhanced" "Detected in many" "oligodendrocyte: 206.9;oligodendrocyte precursor cell: 85.7" "Group enriched" "Detected in many" 5 "Colon Adenocarcinoma (TCGA): 27.1;Ovary Serous Cystadenocarcinoma (TCGA): 14.4;Rectum Adenocarcinoma (TCGA): 29.4;Stomach Adenocarcinoma (TCGA): 9.2;Uterine Corpus Endometrial Carcinoma (TCGA): 35.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 28.1" "Adrenal gland - Adrenal cortex cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells" "Region enriched" "Detected in many" 8 "olfactory bulb: 34.1" "Low region specificity" "Detected in many" HPA012530 Approved Approved "Nucleoplasm,Vesicles,Primary cilium transition zone,Centrosome,Basal body" NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 30: White matter - Myelination" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 55: Myocytes - Oxidative muscle function" 3 "Nucleoplasm, Vesicles, Primary cilium transition zone" "Centrosome, Basal body" "HPA012530: " "unprognostic (1.48e-1)" "potential prognostic unfavorable (5.99e-5)" "unprognostic (2.12e-1)" "unprognostic (4.54e-1)" "unprognostic (6.43e-2)" "unprognostic (7.62e-2)" "potential prognostic favorable (2.80e-4)" "unprognostic (1.87e-3)" "unprognostic (1.39e-1)" "unprognostic (1.08e-3)" "unprognostic (1.95e-1)" "unprognostic (2.08e-1)" "potential prognostic favorable (1.37e-4)" "unprognostic (5.27e-2)" "unprognostic (1.03e-1)" "unprognostic (1.58e-1)" "unprognostic (7.47e-2)" "unprognostic (2.05e-1)" "unprognostic (1.11e-2)" "unprognostic (1.26e-1)" "unprognostic (1.28e-1)" "unprognostic (1.01e-1)" "unprognostic (2.02e-1)" "unprognostic (1.10e-1)" LGR6 FLJ14471 ENSG00000133067 "Leucine rich repeat containing G protein-coupled receptor 6" Q9HBX8 1 202193799-202319781 "G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Wnt signaling pathway" "G-protein coupled receptor, Receptor, Transducer" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 66.9" "Group enriched" "Detected in many" 4 "Bergmann glia: 259.5;Pituicytes/FSCs: 631.9;Pituitary stem cells: 231.6" "Cell type enhanced" "Detected in many" "astrocyte: 74.0;Bergmann glia: 226.5;ependymal cell: 95.8" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 27.1" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 6 "gdT-cell: 15.5;memory CD8 T-cell: 9.1;naive CD8 T-cell: 4.8" "Lineage enriched" "Detected in single" 37 "T-cells: 15.5" "Cancer enhanced" "Detected in many" "Bile duct cancer: 6.9;colorectal cancer: 8.4" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Kidney - Fibroblasts, Pituitary gland - Undifferentiated cells (Pituitary gland), Skeletal muscle - Smooth muscle cells, Spleen - Fibroblasts_1, Testis - Early spermatids" "Region enriched" "Detected in many" 9 "olfactory bulb: 24.4" "Low region specificity" "Detected in many" HPA008556 Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 19: Astrocytes - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" "Plasma membrane" Nucleoplasm "HPA008556: " "unprognostic (4.22e-2)" "potential prognostic favorable (7.82e-4)" "unprognostic (9.42e-2)" "unprognostic (5.72e-3)" "unprognostic (2.55e-1)" "unprognostic (9.50e-2)" "potential prognostic unfavorable (9.35e-5)" "unprognostic (1.51e-3)" "unprognostic (3.33e-1)" "unprognostic (1.31e-1)" "unprognostic (4.74e-3)" "unprognostic (2.64e-1)" "unprognostic (2.95e-2)" "unprognostic (5.79e-2)" "unprognostic (4.49e-2)" "unprognostic (4.67e-2)" "unprognostic (2.30e-1)" "unprognostic (3.92e-2)" "unprognostic (4.04e-2)" "unprognostic (3.81e-2)" "unprognostic (3.37e-2)" "unprognostic (2.72e-1)" "unprognostic (2.32e-3)" "unprognostic (5.94e-2)" "unprognostic (1.95e-1)" "unprognostic (3.96e-2)" LGSN "GLULD1, LGS" ENSG00000146166 "Lengsin, lens protein with glutamine synthetase domain" Q5TDP6 6 63275951-63319983 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "kidney: 1.8;liver: 3.5;placenta: 1.0" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 6.0;Late spermatids: 6.2;Parietal cells: 12.4;Proximal tubule cells: 12.6;Respiratory ciliated cells: 29.5;Sertoli cells: 5.3;Transitional alveolar cells: 5.5" "Cell type enhanced" "Detected in single" "central nervous system macrophage: 1.8" "Cancer enriched" "Detected in some" 7 "Lung Adenocarcinoma (TCGA): 7.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 3.2;lung cancer: 3.2" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Skin - Inner root sheath cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA030957, HPA039983" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 16: Liver & Kidney - Metabolism" "Cluster 6: Non-specific - Immune response" "Cluster 7: Liver cancer - Metabolism" "Cluster 88: Proximal tubular cells - Transmembrane transport" "Nucleoplasm, Vesicles" "HPA030957: , HPA039983: " "unprognostic (4.41e-2)" "unprognostic (1.10e-2)" "unprognostic (1.18e-1)" "unprognostic (6.69e-2)" "unprognostic (9.98e-3)" "unprognostic (6.26e-2)" "unprognostic (1.64e-1)" "unprognostic (1.55e-2)" LHB "CGB4, hLHB, LSH-B" ENSG00000104826 "Luteinizing hormone subunit beta" P01229 19 49015980-49017091 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" Hormone "Cancer-related genes, Disease variant, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 345 "pituitary gland: 4053.3" "Cell type enriched" "Detected in some" 65 "Gonadotrophs: 2250.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Skin Cutaneous Melanoma (TCGA): 3.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Exocrine glandular cells, Pituitary gland - Gonadotropes" "CAB022241, CAB022707, HPA038925" Enhanced "Secreted to blood" Hormone NA NA 1500000 "Cluster 20: Pituitary gland - Hormone signaling" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 72: Neuronal - Signal transduction" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 2 "CAB022241: , CAB022707: , HPA038925: " "unprognostic (5.35e-3)" "unprognostic (2.20e-1)" "unprognostic (2.77e-1)" "unprognostic (7.09e-3)" "unprognostic (1.39e-2)" "unprognostic (3.84e-1)" LHCGR "HHG, LCGR, LGR2, LHR, ULG5" ENSG00000138039 "Luteinizing hormone/choriogonadotropin receptor" P22888 2 48686774-48755730 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "ovary: 2.1;testis: 2.1" "Cell type enriched" "Detected in single" 7 "Adipocytes: 3.4" "Cell type enriched" "Detected in single" 19 "fibroblast: 2.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Adipocytes (Breast)" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB009814, HPA073668" Uncertain Supported "Plasma membrane,Centriolar satellite" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 44: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 89: Adipocytes - Lipid metabolism" 1 "Plasma membrane" "Centriolar satellite" "CAB009814: , HPA073668: " "unprognostic (1.45e-2)" LHFPL1 ENSG00000182508 "LHFPL tetraspan subfamily member 1" Q86WI0 X 112630648-112680054 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.5;salivary gland: 2.7" "Cell type enriched" "Detected in some" 8 "Pituitary stem cells: 149.2" "Cell type enhanced" "Detected in many" "astrocyte: 17.0;central nervous system macrophage: 9.0" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "testis cancer: 3.5" "Low region specificity" "Detected in some" "Region enriched" "Detected in some" 4 "olfactory bulb: 4.5" HPA003029 Uncertain NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 78: Brain - Neuronal signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 28: Astrocytes - Homeostasis & neuron support" 4 "HPA003029: " "unprognostic (3.40e-2)" "unprognostic (5.69e-2)" "unprognostic (3.25e-1)" "unprognostic (3.18e-2)" LHFPL2 KIAA0206 ENSG00000145685 "LHFPL tetraspan subfamily member 2" Q6ZUX7 5 78485215-78770021 "Predicted membrane proteins" Fertilization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epicardial cells: 241.1;Lacrimal acinar cells: 245.5;Microglia: 837.1;Schwann cells: 230.5" "Cell type enriched" "Detected in all" 4 "central nervous system macrophage: 999.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 8.0;plasmacytoid DC: 6.3" "Group enriched" "Detected in many" 9 "dendritic cells: 6.3;granulocytes: 8.0;monocytes: 3.9" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042402, HPA076743" Uncertain Approved "Nuclear bodies,Vesicles,Plasma membrane" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 69: Skin cancer - ECM organization" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 9 "Plasma membrane" "Nuclear bodies, Vesicles" "HPA042402: , HPA076743: " "unprognostic (3.71e-2)" "unprognostic (2.73e-2)" "unprognostic (2.19e-1)" "unprognostic (2.05e-2)" "unprognostic (2.48e-1)" "unprognostic (1.87e-1)" "unprognostic (1.97e-1)" "unprognostic (3.34e-2)" "unprognostic (2.00e-1)" "unprognostic (5.48e-3)" "unprognostic (7.85e-2)" "unprognostic (6.83e-2)" "unprognostic (8.51e-2)" "potential prognostic unfavorable (1.85e-4)" "unprognostic (3.42e-3)" "unprognostic (1.75e-3)" "potential prognostic unfavorable (1.46e-5)" "unprognostic (4.34e-2)" "unprognostic (3.25e-2)" "unprognostic (4.68e-2)" "unprognostic (2.52e-1)" "unprognostic (3.27e-2)" "unprognostic (8.95e-3)" "unprognostic (3.51e-1)" "unprognostic (1.70e-1)" "unprognostic (1.55e-1)" "unprognostic (2.16e-1)" "unprognostic (3.67e-2)" "unprognostic (9.37e-2)" "unprognostic (6.92e-3)" "unprognostic (3.53e-2)" LHFPL3 LHFPL4 ENSG00000187416 "LHFPL tetraspan subfamily member 3" Q86UP9 7 104328603-104908561 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 13.7;retina: 12.5" "Group enriched" "Detected in many" 4 "Cone photoreceptor cells: 1598.1;Oligodendrocyte progenitor cells: 4454.9;Rod photoreceptor cells: 2734.9" "Cell type enhanced" "Detected in all" "oligodendrocyte precursor cell: 4970.5" "Cancer enriched" "Detected in many" 15 "Glioblastoma Multiforme (TCGA): 52.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "skin cancer: 1.0" "Colon - Colon enteroendocrine cells, Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069691 Approved Vesicles No NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 79: Photoreceptor cells - Phototransduction" 2 Vesicles "HPA069691: " "unprognostic (5.65e-2)" "unprognostic (1.60e-1)" "unprognostic (5.93e-2)" "unprognostic (9.88e-2)" "unprognostic (3.70e-2)" "unprognostic (7.26e-2)" "unprognostic (1.36e-1)" "unprognostic (2.42e-1)" "unprognostic (5.43e-2)" "unprognostic (5.35e-2)" "unprognostic (3.65e-1)" "unprognostic (6.80e-3)" LHFPL4 GARLH4 ENSG00000156959 "LHFPL tetraspan subfamily member 4" Q7Z7J7 3 9498361-9553822 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 17.2;pituitary gland: 11.6;retina: 8.7" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 94.7;Brain inhibitory neurons: 93.2;Cone photoreceptor cells: 130.4;Corticotrophs: 67.9;Gonadotrophs: 111.4;Lactotrophs: 93.0;Oligodendrocyte progenitor cells: 55.9;Other brain neurons: 76.4;Pancreatic islet cells: 72.8;Retinal amacrine cells: 104.8;Retinal bipolar cells: 153.5;Retinal ganglion cells: 92.7;Retinal horizontal cells: 64.1;Rod photoreceptor cells: 96.7;Somatotrophs: 74.4;Thyrotrophs: 107.2" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Glioblastoma Multiforme (TCGA): 11.9;Testicular Germ Cell Tumor (TCGA): 8.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Gallbladder cancer: 12.9;Neuroblastoma: 13.0" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041421 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 24: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 18 "Golgi apparatus" Nucleoplasm "HPA041421: " "unprognostic (2.30e-1)" "unprognostic (3.53e-3)" "unprognostic (1.35e-1)" "unprognostic (1.81e-2)" "unprognostic (2.30e-1)" LHFPL5 "DFNB67, dJ510O8.8, MGC33835, Tmhs" ENSG00000197753 "LHFPL tetraspan subfamily member 5" Q8TAF8 6 35797206-35845397 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.2;epididymis: 11.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 57.9;Epicardial cells: 59.1;Neutrophils: 91.5;Pancreatic acinar cells: 66.0;Suprabasal keratinocytes: 55.3" "Cell type enhanced" "Detected in all" "deep-layer corticothalamic and 6b: 127.7" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 12.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 3.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Kidney - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029421, HPA055110" Uncertain Approved Vesicles NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 40: Non-specific - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 11: Neuronal - Sensory perception" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 111 Vesicles "HPA029421: , HPA055110: " "unprognostic (1.03e-1)" "unprognostic (9.94e-2)" "unprognostic (9.65e-2)" "unprognostic (3.98e-3)" "unprognostic (3.15e-2)" "unprognostic (9.35e-3)" "unprognostic (3.69e-2)" "potential prognostic unfavorable (2.86e-7)" "unprognostic (8.85e-2)" "unprognostic (3.18e-1)" "unprognostic (7.43e-2)" "unprognostic (5.83e-2)" "unprognostic (1.31e-2)" "unprognostic (3.57e-3)" "unprognostic (3.34e-1)" "unprognostic (8.72e-2)" "unprognostic (2.82e-3)" "unprognostic (4.18e-2)" "potential prognostic favorable (8.01e-4)" "unprognostic (7.86e-3)" "unprognostic (1.02e-2)" "unprognostic (2.59e-1)" "unprognostic (1.65e-1)" "unprognostic (7.67e-2)" LHFPL6 "LHFP, MGC22429" ENSG00000183722 "LHFPL tetraspan subfamily member 6" Q9Y693 13 39209116-39603528 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 623.4;Bergmann glia: 563.8;Brain excitatory neurons: 545.2;Choroid plexus epithelial cells: 627.3;Fibro-adipogenic progenitors: 934.0;Fibroblasts: 680.9;Lactotrophs: 580.5;Leydig cells: 602.5;Pericytes: 1137.9;Pituicytes/FSCs: 644.1;Retinal amacrine cells: 600.9;Retinal horizontal cells: 947.6;Somatotrophs: 620.6;Vascular smooth muscle cells: 558.8" "Cell type enhanced" "Detected in all" "endothelial cell: 1953.4;fibroblast: 2276.8;pericyte: 2705.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "myeloid DC: 6.2;plasmacytoid DC: 2.1" "Lineage enriched" "Detected in single" 15 "dendritic cells: 6.2" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Breast - Fibroblasts, Colon - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058975 Approved Uncertain Nucleoli NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 19: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 110: Mural cells - ECM organization" 4 Nucleoli "HPA058975: " "unprognostic (2.29e-2)" "unprognostic (2.31e-1)" "unprognostic (3.85e-2)" "unprognostic (1.80e-2)" "unprognostic (9.17e-2)" "unprognostic (9.96e-3)" "unprognostic (1.86e-3)" "unprognostic (2.14e-1)" "unprognostic (4.89e-2)" "unprognostic (5.92e-3)" "unprognostic (1.38e-3)" "potential prognostic unfavorable (6.70e-6)" "unprognostic (6.54e-2)" "unprognostic (9.85e-2)" "unprognostic (1.38e-1)" "unprognostic (7.61e-2)" "unprognostic (9.82e-2)" "unprognostic (3.68e-2)" "unprognostic (3.54e-3)" "unprognostic (1.91e-1)" "unprognostic (4.23e-2)" "unprognostic (5.64e-2)" "unprognostic (2.85e-2)" "unprognostic (1.15e-2)" "unprognostic (5.02e-2)" "unprognostic (3.13e-3)" "unprognostic (9.30e-2)" "unprognostic (4.60e-2)" "unprognostic (1.93e-1)" LHFPL7 "bA9F11.1, TMEM211" ENSG00000206069 "LHFPL tetraspan subfamily member 7" Q6ICI0 22 24935098-24946695 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "cervix: 2.5;salivary gland: 5.6;stomach 1: 3.2" "Cell type enhanced" "Detected in some" "Conjunctival goblet cells: 15.5;Endometrial secretory cells: 6.8;Parietal cells: 17.7;Respiratory deuterosomal cells: 6.2;Respiratory ionocytes: 5.1;Respiratory secretory cells: 7.7;Salivary basal cells: 5.4;Salivary duct cells: 9.8;Salivary ionocytes: 16.3;Submucosal glandular cells: 10.0" "Low cell type specificity" "Detected in some" "Group enriched" "Detected in some" 4 "Colon Adenocarcinoma (TCGA): 5.6;Rectum Adenocarcinoma (TCGA): 8.9;Uterine Corpus Endometrial Carcinoma (TCGA): 4.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 38 "colorectal cancer: 7.5" "Breast - Breast glandular cells (progenitors), Minor Salivary Gland - Minor salivary glandular cells, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA066784 Uncertain NA NA "Cluster 82: Salivary gland - Secretion" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 38: Secretory epithelial cells - Exocrine secretion" "HPA066784: " "unprognostic (3.09e-3)" "unprognostic (1.43e-1)" "unprognostic (1.26e-1)" "unprognostic (3.41e-2)" "unprognostic (1.01e-2)" "unprognostic (2.15e-1)" "unprognostic (2.17e-2)" LHPP HDHD2B ENSG00000107902 "Phospholysine phosphohistidine inorganic pyrophosphate phosphatase" Q9H008 10 124461823-124617888 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "brain: 388.9" "Cell type enhanced" "Detected in all" "Early spermatids: 211.5;Late spermatids: 297.8;Tuft cells: 149.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009163, HPA009269" Enhanced Supported "Nuclear speckles,Cytosol" NA NA 280000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 6: Non-specific - Immune response" "Cluster 52: Non-specific - Mitochondria" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 8 "Nuclear speckles, Cytosol" "HPA009163: , HPA009269: " "unprognostic (1.34e-1)" "unprognostic (1.99e-1)" "unprognostic (6.16e-2)" "unprognostic (1.57e-2)" "unprognostic (3.57e-1)" "unprognostic (1.53e-1)" "unprognostic (1.38e-1)" "unprognostic (2.90e-1)" "unprognostic (3.08e-1)" "unprognostic (2.63e-1)" "unprognostic (6.86e-2)" "unprognostic (2.32e-2)" "potential prognostic favorable (1.45e-4)" "unprognostic (1.19e-2)" "potential prognostic favorable (1.80e-4)" "unprognostic (1.02e-1)" "unprognostic (1.08e-1)" "unprognostic (9.77e-2)" "unprognostic (5.94e-2)" "unprognostic (2.76e-2)" "potential prognostic unfavorable (7.19e-6)" "unprognostic (1.57e-2)" "unprognostic (9.32e-3)" "unprognostic (2.74e-1)" "unprognostic (4.10e-1)" "unprognostic (2.16e-1)" "unprognostic (1.21e-1)" "unprognostic (1.19e-1)" "unprognostic (5.71e-2)" "unprognostic (3.55e-2)" "unprognostic (1.30e-1)" LHX1 "LIM-1, LIM1" ENSG00000273706 "LIM homeobox 1" P48742 17 36936785-36944612 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 23 "brain: 32.2;kidney: 10.0" "Group enriched" "Detected in some" 5 "Distal convoluted tubule cells: 292.6;Renal collecting duct principal cells: 96.3;Renal connecting tubule cells: 196.8" "Cell type enhanced" "Detected in some" "cerebellar inhibitory: 54.2;mammillary body: 98.7;upper rhombic lip: 74.7" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 1.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "thyroid cancer: 2.5" "Region enhanced" "Detected in many" "cerebellum: 19.1" "Region enriched" "Detected in many" 4 "cerebellum: 21.0" "HPA044307, HPA073521, HPA074382" Enhanced Approved "Nucleoplasm,Nuclear membrane,Golgi apparatus" NA NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 25: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 7 Nucleoplasm "Nuclear membrane, Golgi apparatus" "HPA044307: , HPA073521: , HPA074382: " "unprognostic (9.60e-3)" "unprognostic (1.17e-1)" "unprognostic (2.55e-1)" "unprognostic (1.72e-1)" LHX2 "hLhx2, LH-2" ENSG00000106689 "LIM homeobox 2" P50458 9 124001670-124033301 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 82.0;retina: 31.7" "Cell type enhanced" "Detected in some" "Astrocytes: 72.8;Early spermatids: 48.6;Hepatic stellate cells: 25.8;Late spermatids: 36.5;Müller glia: 290.5;Pituicytes/FSCs: 91.5;Retinal pigment epithelial cells: 123.6" "Group enriched" "Detected in many" 5 "amygdala excitatory: 41.0;astrocyte: 40.2;deep-layer intratelencephalic: 54.0;hippocampal CA1-3: 33.3;hippocampal CA4: 82.9;hippocampal dentate gyrus: 21.9;LAMP5-LHX6 and Chandelier: 23.5;miscellaneous: 38.9;thalamic excitatory: 21.3;upper-layer intratelencephalic: 42.0" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 38.4" "Group enriched" "Detected in all" 5 "amygdala: 63.8;basal ganglia: 64.6;cerebral cortex: 89.8;hippocampal formation: 86.1;white matter: 55.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 20.9" "Liver - Hepatic stellate cells, Skin - Outer root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA000838 Supported Approved Nucleoplasm NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 11: Muller glia cells - Retinal homeostasis" 31 Nucleoplasm "HPA000838: " "unprognostic (1.19e-1)" "unprognostic (1.12e-3)" "unprognostic (2.85e-2)" "unprognostic (2.28e-2)" "unprognostic (1.33e-1)" "unprognostic (2.05e-2)" "unprognostic (3.60e-2)" "unprognostic (7.55e-3)" "unprognostic (2.01e-3)" "unprognostic (1.37e-2)" "unprognostic (3.93e-2)" "unprognostic (6.82e-2)" "unprognostic (1.87e-1)" "unprognostic (1.57e-1)" "unprognostic (9.44e-3)" "unprognostic (1.36e-1)" LHX3 ENSG00000107187 "LIM homeobox 3" Q9UBR4 9 136196250-136205128 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 48 "pituitary gland: 49.1" "Cell type enriched" "Detected in some" 9 "Pituitary stem cells: 200.9" "Cell type enriched" "Detected in single" 10 "splatter: 1.0" "Cancer enhanced" "Detected in single" "Bladder Urothelial Carcinoma (TCGA): 1.1" "Region enhanced" "Detected in some" "pons: 2.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 2.3;lung cancer: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 20: Pituitary gland - Hormone signaling" "Cluster 43: Hindbrain - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 14 "unprognostic (2.27e-1)" LHX4 Gsh4 ENSG00000121454 "LIM homeobox 4" Q969G2 1 180230264-180278984 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant, Dwarfism, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "retina: 14.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 24.3;Cone photoreceptor cells: 60.0;Early spermatids: 81.4;Epicardial cells: 29.6;Late spermatids: 160.8;Retinal bipolar cells: 145.7" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "pons and medulla: 1.3" "Group enriched" "Detected in some" 5 "pons: 1.0;spinal cord: 3.1" HPA055705 Approved "Nuclear speckles" NA NA "Cluster 42: Retina - Visual perception" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 1: Neuronal - Visual perception" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 57 "Nuclear speckles" "HPA055705: " "unprognostic (1.72e-1)" "unprognostic (5.98e-2)" "unprognostic (1.18e-1)" "unprognostic (2.53e-1)" LHX5 ENSG00000089116 "LIM homeobox 5" Q9H2C1 12 113462033-113472280 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 23 "brain: 3.3;stomach 1: 1.3" "Cell type enriched" "Detected in some" 6 "Neuroendocrine cells: 18.7" "Cell type enhanced" "Detected in some" "cerebellar inhibitory: 19.3;mammillary body: 6.5;midbrain-derived inhibitory: 7.6" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "medulla oblongata: 10.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 1.1;head and neck cancer: 1.5" "Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA053908 Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 109: Neurons - Neuronal signaling" 17 Cytosol "Nucleoplasm, Nuclear bodies" "HPA053908: " "unprognostic (4.55e-2)" "unprognostic (1.11e-2)" "unprognostic (1.05e-1)" LHX6 "hLHX6, LHX6.1" ENSG00000106852 "LIM homeobox 6" Q9UPM6 9 122202577-122229626 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 15.1;brain: 13.9" "Group enriched" "Detected in some" 6 "Early spermatids: 93.9;Late spermatids: 368.2" "Cell type enhanced" "Detected in some" "LAMP5-LHX6 and Chandelier: 151.5;MGE interneuron: 127.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "Gallbladder cancer: 34.4" "Adipose visceral - Endothelial cells, Colon - Endothelial cells, Minor Salivary Gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "amygdala: 8.8;basal ganglia: 9.6;cerebral cortex: 10.2;hippocampal formation: 9.5;hypothalamus: 2.9" "HPA002269, HPA047854" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 23 Nucleoplasm Cytosol "HPA002269: , HPA047854: " "unprognostic (1.53e-1)" "unprognostic (1.69e-1)" "unprognostic (1.53e-2)" "unprognostic (1.26e-1)" "unprognostic (1.41e-1)" "unprognostic (4.81e-2)" "unprognostic (3.49e-2)" "unprognostic (6.50e-2)" "unprognostic (7.65e-2)" "unprognostic (9.00e-2)" "unprognostic (9.46e-3)" "unprognostic (1.61e-1)" "unprognostic (6.68e-2)" "unprognostic (7.78e-2)" "unprognostic (2.08e-1)" "unprognostic (6.30e-2)" "unprognostic (1.82e-1)" "unprognostic (5.47e-2)" "unprognostic (2.10e-1)" "unprognostic (1.41e-1)" "unprognostic (3.02e-1)" "unprognostic (1.01e-1)" "unprognostic (5.00e-3)" "unprognostic (2.35e-3)" "unprognostic (1.89e-1)" "unprognostic (1.46e-1)" "unprognostic (2.25e-2)" LHX8 Lhx7 ENSG00000162624 "LIM homeobox 8" Q68G74 1 75128434-75161533 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 1.4;salivary gland: 1.9" "Cell type enriched" "Detected in some" 19 "Oocytes: 557.2" "Group enriched" "Detected in some" 5 "ependymal cell: 3.0;splatter: 3.3" "Low cancer specificity" "Detected in some" "Group enriched" "Detected in some" 6 "cerebral cortex: 17.9;hypothalamus: 11.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 5.1;Neuroblastoma: 4.0" "Minor Salivary Gland - Fibroblasts, Testis - Spermatogonia" "Region enhanced" "Detected in many" "basal ganglia: 9.9" "Region enriched" "Detected in some" 5 "basal ganglia: 15.9" HPA071806 Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 33: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 41: Oocytes - Oogenesis" 35 "Nucleoplasm, Nucleoli" Cytosol "HPA071806: " "unprognostic (9.58e-2)" "unprognostic (1.07e-1)" LHX9 ENSG00000143355 "LIM homeobox 9" Q9NQ69 1 197911902-197935478 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "ovary: 17.8" "Group enriched" "Detected in some" 4 "Leydig cells: 137.2;Peritubular myoid cells: 62.0;Retinal amacrine cells: 60.7" "Cell type enhanced" "Detected in some" "ependymal cell: 10.6;splatter: 9.3;thalamic excitatory: 42.4" "Cancer enriched" "Detected in many" 10 "Kidney Chromophobe (TCGA): 36.2" "Region enhanced" "Detected in all" "midbrain: 36.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 18.5" "Adipose visceral - Mesothelial cells" "Group enriched" "Detected in many" 4 "hippocampal formation: 6.3;midbrain: 17.3;thalamus: 12.2" "Group enriched" "Detected in many" 5 "midbrain: 20.4;pons: 8.1;thalamus: 17.3" HPA009695 Uncertain Approved Nucleoplasm NA NA "Cluster 75: Ovary - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 94: Gonadal somatic cells - Mixed function" 5 Nucleoplasm "HPA009695: " "unprognostic (5.32e-2)" "unprognostic (9.14e-2)" "unprognostic (1.05e-1)" "unprognostic (7.21e-2)" "unprognostic (1.23e-1)" "unprognostic (2.51e-1)" "unprognostic (9.10e-3)" "unprognostic (1.65e-1)" "unprognostic (3.01e-3)" LIAS LAS ENSG00000121897 "Lipoic acid synthetase" O43766 4 39459004-39485109 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 131.2;Late primary spermatocytes: 87.6;Late spermatids: 153.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018842, HPA019076" Approved Supported Approved Nucleoplasm,Mitochondria Yes No "Cluster 24: Non-specific - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 13: Non-specific - Mixed function" "Cluster 7: Non-specific - Transcription" 1 Nucleoplasm Mitochondria "HPA018842: , HPA019076: " "unprognostic (2.68e-2)" "unprognostic (1.22e-2)" "unprognostic (2.09e-1)" "unprognostic (3.63e-2)" "unprognostic (1.31e-1)" "unprognostic (1.49e-1)" "unprognostic (1.51e-1)" "unprognostic (1.88e-2)" "unprognostic (4.47e-2)" "unprognostic (8.43e-2)" "validated prognostic favorable (2.03e-5)" "validated prognostic favorable (4.23e-4)" "unprognostic (3.42e-3)" "unprognostic (7.45e-2)" "unprognostic (3.13e-1)" "unprognostic (1.38e-1)" "unprognostic (1.10e-1)" "unprognostic (9.01e-3)" "unprognostic (4.90e-2)" "unprognostic (3.05e-2)" "unprognostic (1.30e-1)" "unprognostic (1.86e-1)" "unprognostic (1.06e-1)" "unprognostic (5.69e-3)" "unprognostic (9.16e-2)" "potential prognostic favorable (1.24e-4)" "unprognostic (1.53e-1)" "unprognostic (3.96e-2)" "unprognostic (3.72e-1)" "unprognostic (2.66e-2)" "unprognostic (8.28e-3)" LIF "CDF, DIA, HILDA" ENSG00000128342 "LIF interleukin 6 family cytokine" P15018 22 30240453-30246759 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 44.7;urinary bladder: 84.6" "Cell type enhanced" "Detected in many" "Breast secretory cells: 189.2;Endometrial glandular cells: 136.1;Endometrial luminal cells: 286.7;Endometrial secretory cells: 370.1;Epididymal basal cells: 120.7;Fibroblasts: 56.7;Innate lymphoid cells: 55.8;Mast cells: 115.5;Pancreatic duct cells: 105.9" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 1.6;fibroblast: 1.1" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "choroid plexus: 10.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Ductal cells, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018844, CAB025985" Uncertain Supported Cytosol "Secreted in other tissues" Cytokine NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 12: Non-specific - Vasculature" "Cluster 69: Skin cancer - ECM organization" "Cluster 17: Non-specific - RNA processing" 5 Cytosol "CAB025985: , HPA018844: " "unprognostic (2.29e-2)" "unprognostic (1.87e-2)" "unprognostic (5.58e-2)" "potential prognostic unfavorable (2.62e-6)" "unprognostic (4.09e-1)" "unprognostic (1.23e-1)" "unprognostic (5.04e-3)" "unprognostic (1.05e-2)" "unprognostic (3.55e-3)" "unprognostic (5.48e-2)" "potential prognostic unfavorable (5.45e-4)" "unprognostic (5.78e-2)" "unprognostic (3.36e-2)" "unprognostic (4.54e-3)" "unprognostic (1.95e-1)" "unprognostic (5.70e-2)" "unprognostic (1.11e-2)" "unprognostic (9.48e-3)" "unprognostic (1.02e-1)" "unprognostic (3.36e-2)" "unprognostic (1.08e-1)" "unprognostic (4.59e-2)" "unprognostic (1.46e-2)" "unprognostic (9.07e-2)" "unprognostic (2.05e-1)" "unprognostic (1.55e-2)" "unprognostic (2.84e-2)" "unprognostic (1.94e-1)" "unprognostic (2.95e-1)" "unprognostic (6.54e-2)" "unprognostic (1.46e-1)" LIFR CD118 ENSG00000113594 "LIF receptor subunit alpha" P42702 5 38474668-38608354 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 658.3;Bergmann glia: 851.8;Ependymal cells: 325.0;Fibro-adipogenic progenitors: 383.1;Leydig cells: 331.8;Parietal cells: 606.4;Salivary myoepithelial cells: 319.5;Vascular endothelial cells: 874.1" "Cell type enhanced" "Detected in all" "astrocyte: 876.6;Bergmann glia: 904.8;endothelial cell: 639.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB080607, CAB080608" Supported "Intracellular and membrane" Receptor NA NA 200000 "Cluster 75: Ovary - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 6 "CAB080607: , CAB080608: " "unprognostic (4.87e-2)" "unprognostic (1.14e-2)" "unprognostic (3.63e-2)" "unprognostic (2.53e-1)" "unprognostic (1.23e-1)" "unprognostic (2.53e-1)" "unprognostic (2.74e-1)" "unprognostic (1.23e-1)" "unprognostic (2.36e-1)" "validated prognostic favorable (4.76e-9)" "validated prognostic favorable (2.39e-4)" "potential prognostic favorable (2.11e-7)" "unprognostic (9.21e-2)" "potential prognostic favorable (4.23e-4)" "potential prognostic favorable (8.96e-4)" "unprognostic (4.50e-1)" "unprognostic (1.53e-1)" "unprognostic (8.73e-3)" "unprognostic (2.19e-1)" "unprognostic (3.32e-2)" "potential prognostic favorable (7.14e-4)" "unprognostic (5.43e-3)" "unprognostic (6.68e-2)" "unprognostic (3.24e-2)" "unprognostic (5.66e-3)" "unprognostic (3.53e-1)" "unprognostic (1.77e-2)" "unprognostic (6.85e-2)" LIG1 "hLig1, LIGI" ENSG00000105486 "DNA ligase 1" P18858 19 48115445-48170603 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA recombination, DNA repair, DNA replication" Ligase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 29.1;lymphoid tissue: 20.3" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 100.5;Respiratory deuterosomal cells: 59.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037015, HPA041431, HPA048071" Approved Supported "Nucleoplasm,Golgi apparatus,Vesicles" Yes No 3400 "Cluster 16: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 4: Non-specific - Transcription" "Cluster 27: Non-specific - Cell proliferation" 10 Nucleoplasm "Golgi apparatus, Vesicles" "CAB037015: , HPA041431: , HPA048071: " "unprognostic (6.89e-2)" "unprognostic (1.38e-1)" "unprognostic (1.07e-1)" "unprognostic (1.38e-1)" "unprognostic (2.97e-2)" "unprognostic (4.55e-2)" "unprognostic (3.21e-1)" "unprognostic (4.27e-1)" "unprognostic (3.47e-2)" "potential prognostic unfavorable (1.39e-4)" "potential prognostic favorable (3.74e-6)" "unprognostic (1.12e-1)" "unprognostic (3.20e-1)" "unprognostic (1.49e-2)" "unprognostic (2.16e-2)" "unprognostic (4.00e-3)" "unprognostic (7.98e-3)" "unprognostic (2.20e-1)" "unprognostic (3.25e-1)" "unprognostic (1.96e-1)" "unprognostic (3.19e-2)" "unprognostic (2.74e-1)" "unprognostic (4.42e-2)" "unprognostic (1.10e-2)" "unprognostic (6.72e-2)" "unprognostic (2.30e-2)" "potential prognostic unfavorable (9.15e-4)" "unprognostic (1.57e-1)" "unprognostic (1.69e-1)" "unprognostic (9.59e-2)" "unprognostic (3.92e-2)" LIG3 "LIG2, LIG3alpha" ENSG00000005156 "DNA ligase 3" P49916 17 34980512-35009743 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA recombination, DNA repair, DNA replication" Ligase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epicardial cells: 95.5;Late spermatids: 121.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006723, CAB080348" Supported Supported Nucleoplasm NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 39: Testis - Nuclear processes" "Cluster 16: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 48 Nucleoplasm "CAB080348: , HPA006723: " "unprognostic (1.39e-1)" "unprognostic (1.68e-2)" "unprognostic (3.12e-1)" "unprognostic (1.52e-1)" "unprognostic (7.02e-2)" "potential prognostic unfavorable (2.66e-4)" "unprognostic (1.29e-1)" "unprognostic (2.26e-2)" "unprognostic (2.22e-1)" "unprognostic (5.33e-3)" "potential prognostic favorable (7.71e-4)" "unprognostic (3.90e-3)" "unprognostic (2.25e-2)" "unprognostic (2.96e-2)" "unprognostic (2.92e-2)" "unprognostic (3.89e-2)" "unprognostic (9.62e-3)" "unprognostic (1.90e-1)" "unprognostic (1.34e-2)" "unprognostic (2.63e-2)" "unprognostic (3.46e-2)" "unprognostic (1.42e-3)" "unprognostic (1.25e-1)" "unprognostic (1.53e-1)" "potential prognostic favorable (9.51e-4)" "unprognostic (9.59e-3)" "potential prognostic unfavorable (9.01e-5)" "unprognostic (2.28e-1)" "unprognostic (2.31e-1)" "unprognostic (3.67e-3)" "unprognostic (3.58e-2)" LIG4 ENSG00000174405 "DNA ligase 4" P49917 13 108207439-108218368 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA recombination, DNA repair" Ligase "Cancer-related genes, Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001334, HPA057325" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 23: Choroid plexus - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 41 Nucleoplasm Vesicles "HPA001334: , HPA057325: " "unprognostic (9.10e-3)" "unprognostic (1.78e-1)" "unprognostic (5.65e-2)" "unprognostic (2.85e-2)" "unprognostic (5.59e-2)" "unprognostic (8.79e-2)" "unprognostic (2.11e-1)" "unprognostic (8.35e-2)" "unprognostic (1.17e-1)" "unprognostic (5.53e-1)" "unprognostic (2.79e-2)" "unprognostic (2.15e-2)" "potential prognostic favorable (5.29e-4)" "unprognostic (3.42e-1)" "unprognostic (2.20e-3)" "unprognostic (1.34e-1)" "unprognostic (1.43e-1)" "unprognostic (1.13e-1)" "unprognostic (1.75e-1)" "unprognostic (2.03e-1)" "unprognostic (2.00e-1)" "unprognostic (3.24e-2)" "unprognostic (5.20e-3)" "unprognostic (1.08e-1)" "unprognostic (2.63e-1)" "unprognostic (5.36e-2)" "unprognostic (1.15e-1)" "unprognostic (2.24e-1)" "unprognostic (2.54e-1)" "unprognostic (9.35e-3)" "unprognostic (2.14e-1)" LILRA1 "CD85i, LIR-6, LIR6" ENSG00000104974 "Leukocyte immunoglobulin like receptor A1" O75019 19 54593582-54602381 "CD markers, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 13.2" "Cell type enhanced" "Detected in some" "cDC: 1.9;Kupffer cells: 5.1;Macrophages: 2.9;Microglia: 16.1;monocytes: 10.7;Neutrophils: 4.3" "Group enriched" "Detected in some" 54 "central nervous system macrophage: 20.6;leukocyte: 9.5" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 1.3" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 126.7;non-classical monocyte: 169.8" "Lineage enriched" "Detected in many" 5 "monocytes: 169.8" "Not detected" "Not detected" "Adrenal gland - Macrophages, Kidney - Macrophages, Lung - Neutrophils_2, Prostate - Macrophages, Spleen - Macrophages" NA NA 6500000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" "unprognostic (5.03e-2)" "unprognostic (2.50e-1)" "unprognostic (3.23e-2)" "potential prognostic favorable (6.40e-4)" LILRA2 "CD85h, ILT1, LIR-7, LIR7" ENSG00000239998 "Leukocyte immunoglobulin like receptor A2" Q8N149 19 54572920-54590287 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.5;lymphoid tissue: 56.9" "Cell type enhanced" "Detected in some" "cDC: 3.9;Kupffer cells: 9.2;Macrophages: 7.2;Microglia: 34.6;Monocyte progenitors: 10.6;monocytes: 16.9;Neutrophil progenitors: 4.2;Neutrophils: 39.9" "Cell type enriched" "Detected in some" 5 "central nervous system macrophage: 43.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 31.8" "Group enriched" "Detected in many" 6 "granulocytes: 31.8;monocytes: 11.7" "Cancer enriched" "Detected in single" 7 "Leukemia: 2.6" "Adipose subcutaneous - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Neutrophils_2, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Thyroid gland - Macrophages" "Secreted to blood" Receptor NA NA 18000000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 5: Spleen - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 35: RS4;11 - Unknown function" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" "unprognostic (2.32e-1)" "unprognostic (5.71e-2)" "unprognostic (8.99e-2)" "unprognostic (3.28e-1)" "unprognostic (3.40e-3)" "unprognostic (1.09e-2)" "unprognostic (2.90e-3)" "unprognostic (9.16e-2)" "unprognostic (1.74e-1)" "unprognostic (1.48e-1)" "unprognostic (2.87e-1)" LILRA4 "CD85g, ILT7" ENSG00000239961 "Leukocyte immunoglobulin like receptor A4" P59901 19 54333185-54339162 "CD markers, Predicted membrane proteins" "Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 4.3;lymphoid tissue: 10.1" "Cell type enriched" "Detected in some" 12 "pDCs: 79.3" "Cell type enriched" "Detected in single" 91 "central nervous system macrophage: 9.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in some" 21 "plasmacytoid DC: 176.0" "Lineage enriched" "Detected in many" 21 "dendritic cells: 176.0" "Not detected" "Not detected" "Minor Salivary Gland - Macrophages, Spleen - B-cells (Spleen)" HPA049418 Approved NA NA 3800000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 5: Spleen - Immune response" "Cluster 30: White matter - Myelination" "Cluster 55: Lymphoma - Immune response" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 1 "HPA049418: " "unprognostic (8.19e-2)" "unprognostic (4.09e-2)" "unprognostic (5.33e-2)" LILRA5 "CD85, CD85f, ILT11, LILRB7, LIR9" ENSG00000187116 "Leukocyte immunoglobulin like receptor A5" A6NI73 19 54307070-54313166 "CD markers, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 40.5;lymphoid tissue: 73.4" "Group enriched" "Detected in some" 4 "monocytes: 11.9;Neutrophils: 23.4" "Cell type enriched" "Detected in single" 119 "leukocyte: 11.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 5 "classical monocyte: 128.6;intermediate monocyte: 252.9;neutrophil: 137.5;non-classical monocyte: 312.7" "Group enriched" "Detected in many" 6 "granulocytes: 137.5;monocytes: 312.7" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Colon - Neutrophils, Heart muscle - Neutrophils, Kidney - Macrophages, Liver - Neutrophils, Lung - Neutrophils_2, Prostate - Macrophages, Skeletal muscle - Neutrophils, Spleen - Neutrophils_2, Thyroid gland - Neutrophils" "Secreted to blood" Receptor NA NA 950000 "Cluster 40: Monocytes - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" "unprognostic (1.11e-1)" "unprognostic (3.22e-2)" "potential prognostic unfavorable (9.55e-4)" "unprognostic (3.03e-2)" "unprognostic (1.02e-1)" "unprognostic (2.59e-2)" "unprognostic (3.22e-1)" "unprognostic (6.25e-2)" "unprognostic (6.64e-2)" "unprognostic (5.63e-2)" "unprognostic (8.45e-3)" "unprognostic (1.47e-1)" "unprognostic (9.43e-2)" "unprognostic (1.79e-1)" "unprognostic (3.69e-2)" LILRA6 "CD85b, ILT8, LILRB6" ENSG00000244482 "Leukocyte immunoglobulin like receptor A6" Q6PI73 19 54236592-54242791 "Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "lung: 8.6;lymphoid tissue: 16.2" "Cell type enhanced" "Detected in some" "monocytes: 3.2;Neutrophils: 2.0" "Cell type enriched" "Detected in some" 6 "leukocyte: 7.3" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "classical monocyte: 3.5;intermediate monocyte: 3.9;neutrophil: 8.4" "Group enriched" "Detected in many" 27 "granulocytes: 8.4;monocytes: 3.9" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Kidney - Macrophages, Lung - Neutrophils_2, Prostate - Macrophages, Spleen - Neutrophils_2" HPA026985 Approved "Plasma membrane,Cytosol" NA NA 6200000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 5: Spleen - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 102: Non-specific - Mixed function" "Plasma membrane" Cytosol "HPA026985: " "unprognostic (2.46e-1)" "unprognostic (9.16e-3)" "unprognostic (1.51e-1)" "unprognostic (7.33e-2)" "unprognostic (8.22e-2)" LILRB1 "CD85, CD85j, ILT2, LIR-1, LIR1, MIR-7, PIR-B, PIRB" ENSG00000104972 "Leukocyte immunoglobulin like receptor B1" 19 54617158-54638022 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 48.0" "Group enriched" "Detected in some" 6 "Microglia: 73.1;monocytes: 22.1" "Group enriched" "Detected in some" 48 "central nervous system macrophage: 85.4;leukocyte: 44.3" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "intermediate monocyte: 52.6;non-classical monocyte: 74.2" "Lineage enriched" "Detected in many" 11 "monocytes: 74.2" "Group enriched" "Detected in some" 40 "Leukemia: 2.3;lymphoma: 6.1;Myeloma: 3.3" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Liver - Kupffer cells, Prostate - T-cells" "Intracellular and membrane" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 102: Non-specific - Mixed function" 1 "unprognostic (7.16e-3)" "unprognostic (1.32e-1)" "unprognostic (2.54e-1)" "unprognostic (2.00e-1)" "unprognostic (3.51e-2)" "unprognostic (3.60e-1)" "unprognostic (1.85e-2)" LILRB2 "CD85d, ILT4, LIR-2, LIR2, MIR-10, MIR10" ENSG00000131042 "Leukocyte immunoglobulin like receptor B2" Q8N423 19 54273812-54281184 "CD markers, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 33.1;lung: 14.3;lymphoid tissue: 48.8" "Cell type enhanced" "Detected in some" "cDC: 8.5;Kupffer cells: 10.2;Macrophages: 8.6;Microglia: 12.5;monocytes: 37.8;Neutrophil progenitors: 5.3;Neutrophils: 17.4" "Group enriched" "Detected in some" 144 "central nervous system macrophage: 17.8;leukocyte: 50.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "classical monocyte: 61.3;intermediate monocyte: 131.4;neutrophil: 63.2;non-classical monocyte: 152.2" "Group enriched" "Detected in many" 6 "granulocytes: 63.2;monocytes: 152.2" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Kidney - Macrophages, Lung - Neutrophils_2, Minor Salivary Gland - Macrophages, Pituitary gland - Macrophages" NA NA 23000000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 102: Non-specific - Mixed function" 6 "unprognostic (5.92e-3)" "unprognostic (8.63e-2)" "unprognostic (9.88e-2)" "unprognostic (3.71e-3)" "unprognostic (1.88e-1)" "unprognostic (3.95e-2)" "unprognostic (3.12e-2)" "unprognostic (3.52e-1)" "unprognostic (4.52e-2)" "unprognostic (9.29e-2)" "unprognostic (8.20e-2)" "unprognostic (1.99e-1)" LILRB3 "CD85a, HL9, ILT5, LIR-3, LIR3, PIR-B, PIRB" ENSG00000204577 "Leukocyte immunoglobulin like receptor B3" O75022 19 54216278-54223506 "CD markers, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 18.8;lymphoid tissue: 37.9" "Group enriched" "Detected in some" 6 "monocytes: 21.0;Neutrophils: 61.2" "Cell type enriched" "Detected in some" 5 "leukocyte: 26.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 43.2" "Group enriched" "Detected in many" 4 "granulocytes: 43.2;monocytes: 15.3" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Liver - Neutrophils, Lung - Neutrophils_2, Pituitary gland - Macrophages, Spleen - Neutrophils_2, Thyroid gland - Neutrophils" HPA026985 Approved "Plasma membrane,Cytosol" NA NA 5000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 5: Spleen - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 55: Lymphoma - Immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" "Plasma membrane" Cytosol "HPA026985: " "unprognostic (3.18e-3)" "unprognostic (5.14e-3)" "potential prognostic unfavorable (1.31e-5)" "unprognostic (1.01e-1)" "unprognostic (2.63e-1)" "unprognostic (5.16e-2)" "unprognostic (1.00e-3)" "unprognostic (1.20e-1)" "unprognostic (5.06e-2)" "unprognostic (5.28e-2)" "unprognostic (1.63e-2)" "unprognostic (1.78e-1)" "unprognostic (1.18e-2)" LILRB4 "CD85k, HM18, ILT3, LIR-5, LIR5" ENSG00000186818 "Leukocyte immunoglobulin like receptor B4" Q8NHJ6 19 54643889-54670359 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 13.5;lung: 13.1;lymphoid tissue: 17.7" "Cell type enriched" "Detected in some" 13 "Microglia: 139.1" "Cell type enriched" "Detected in some" 20 "central nervous system macrophage: 157.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 37.8" "Group enriched" "Detected in many" 43 "dendritic cells: 37.8;monocytes: 11.0" "Cancer enriched" "Detected in some" 5 "Myeloma: 28.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid gland - Macrophages" HPA052807 Approved NA NA 210000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 5: Spleen - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 3 "HPA052807: " "unprognostic (1.88e-1)" "unprognostic (2.10e-2)" "unprognostic (1.67e-1)" "unprognostic (3.42e-1)" "unprognostic (2.02e-1)" "unprognostic (2.08e-1)" "unprognostic (1.97e-1)" "unprognostic (1.72e-1)" "unprognostic (6.04e-2)" "unprognostic (1.62e-1)" "unprognostic (9.71e-2)" "unprognostic (2.73e-1)" "unprognostic (4.98e-2)" "unprognostic (6.09e-2)" "unprognostic (3.58e-2)" "unprognostic (1.57e-1)" "unprognostic (3.02e-2)" "unprognostic (1.93e-2)" "unprognostic (1.84e-1)" "unprognostic (2.80e-1)" "unprognostic (3.59e-1)" "unprognostic (1.80e-2)" "unprognostic (4.24e-1)" "unprognostic (2.20e-2)" "unprognostic (4.14e-2)" "unprognostic (3.51e-1)" "unprognostic (1.84e-1)" "unprognostic (2.81e-1)" "unprognostic (2.15e-1)" LILRB5 "CD85c, LIR-8, LIR8" ENSG00000105609 "Leukocyte immunoglobulin like receptor B5" O75023 19 54249421-54257301 "CD markers, Plasma proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 16.0;lymphoid tissue: 45.4" "Group enriched" "Detected in some" 6 "Kupffer cells: 4.1;Macrophages: 14.0" "Cell type enriched" "Detected in some" 8 "central nervous system macrophage: 10.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Minor Salivary Gland - Macrophages, Skeletal muscle - Macrophages, Thyroid gland - Macrophages" HPA012069 Approved NA NA 14000000 "Cluster 5: Spleen - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 56: Non-specific - Sensory perception" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" "HPA012069: " "unprognostic (3.53e-2)" "unprognostic (1.16e-2)" "unprognostic (3.43e-2)" "potential prognostic favorable (3.29e-4)" "unprognostic (3.29e-2)" "unprognostic (2.56e-3)" "unprognostic (1.41e-2)" "unprognostic (1.67e-1)" "unprognostic (2.24e-1)" "potential prognostic unfavorable (3.15e-4)" "unprognostic (4.68e-2)" "unprognostic (7.85e-2)" "unprognostic (8.23e-2)" LIM2 "MP17, MP19" ENSG00000105370 "Lens intrinsic membrane protein 2" P55344 19 51379909-51387974 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Eye lens protein" "Cataract, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Early spermatids: 1.2;Esophageal apical cells: 1.4;Late primary spermatocytes: 1.4;Neutrophils: 1.8;NK-cells: 4.7" "Cell type enhanced" "Detected in single" "leukocyte: 1.4" "Cancer enriched" "Detected in single" 36 "Testicular Germ Cell Tumor (TCGA): 30.9" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 7 "gdT-cell: 11.3" "Lineage enriched" "Detected in many" 7 "T-cells: 11.3" "Cancer enriched" "Detected in single" 7 "Sarcoma: 1.5" "Lung - NK-cells (Lung)" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 54: Non-specific - Transcription" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" "unprognostic (1.78e-1)" LIMA1 EPLIN ENSG00000050405 "LIM domain and actin binding 1" Q9UHB6 12 50175788-50283520 "Predicted intracellular proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 906.4;Epididymal basal cells: 736.4;Extravillous trophoblasts: 864.0" "Cell type enhanced" "Detected in all" "upper rhombic lip: 441.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023871, HPA052645" Enhanced Approved "Plasma membrane,Actin filaments,Focal adhesion sites,Cytosol" NA NA 47000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 77: Intestine - Digestion" "Cluster 25: Non-specific - Transcription" "Cluster 72: Neuronal - Signal transduction" "Cluster 89: Adipocytes - Lipid metabolism" 50 "Plasma membrane, Actin filaments" "Focal adhesion sites, Cytosol" "HPA023871: , HPA052645: " "unprognostic (5.10e-2)" "unprognostic (2.04e-2)" "unprognostic (2.73e-1)" "unprognostic (7.91e-2)" "unprognostic (2.24e-2)" "unprognostic (8.03e-3)" "unprognostic (9.39e-2)" "unprognostic (2.18e-2)" "potential prognostic unfavorable (3.37e-5)" "unprognostic (1.24e-1)" "potential prognostic favorable (1.01e-7)" "unprognostic (2.28e-2)" "unprognostic (8.98e-2)" "unprognostic (9.73e-2)" "unprognostic (1.60e-1)" "unprognostic (4.80e-2)" "unprognostic (2.70e-2)" "unprognostic (2.32e-1)" "unprognostic (2.29e-2)" "unprognostic (1.23e-1)" "unprognostic (1.39e-3)" "unprognostic (1.22e-3)" "unprognostic (6.97e-2)" "unprognostic (2.39e-1)" "unprognostic (1.16e-1)" "unprognostic (1.49e-2)" "unprognostic (2.81e-2)" "unprognostic (3.35e-1)" "unprognostic (5.90e-2)" "unprognostic (2.23e-1)" "unprognostic (5.36e-2)" LIMCH1 "DKFZP686A01247, LIMCH1A, LMO7B" ENSG00000064042 "LIM and calponin homology domains 1" Q9UPQ0 4 41359607-41700044 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 191.0;tongue: 258.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 1912.1;Alveolar cells type 2: 983.4;Myonuclei: 1085.8;Oligodendrocytes: 1182.4;Prostatic glandular cells: 1163.2;Renal connecting tubule cells: 1116.5;Salivary acinar cells: 1040.8;Transitional alveolar cells: 1343.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 80.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "myeloid DC: 1.3" "Lineage enriched" "Detected in single" 8 "dendritic cells: 1.3" "Low cancer specificity" "Detected in many" "Pituitary gland - Undifferentiated cells (Pituitary gland), Spleen - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004184, HPA063840" Uncertain Supported "Actin filaments" NA NA 3100 "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 3 "Actin filaments" "HPA004184: , HPA063840: " "unprognostic (9.79e-3)" "potential prognostic unfavorable (4.86e-6)" "unprognostic (1.28e-1)" "unprognostic (6.90e-3)" "unprognostic (1.37e-1)" "unprognostic (5.57e-3)" "unprognostic (3.10e-2)" "unprognostic (1.28e-1)" "unprognostic (2.44e-1)" "unprognostic (2.84e-2)" "validated prognostic favorable (7.67e-9)" "validated prognostic favorable (3.12e-5)" "unprognostic (1.58e-3)" "unprognostic (1.99e-2)" "unprognostic (6.20e-3)" "unprognostic (1.03e-2)" "unprognostic (1.34e-1)" "unprognostic (7.47e-2)" "unprognostic (3.43e-3)" "unprognostic (1.32e-2)" "unprognostic (2.27e-1)" "unprognostic (4.73e-2)" "unprognostic (8.14e-3)" "unprognostic (2.46e-1)" "unprognostic (6.23e-2)" "unprognostic (9.41e-2)" "unprognostic (1.13e-1)" "unprognostic (1.20e-1)" "unprognostic (9.25e-2)" "unprognostic (7.92e-2)" "unprognostic (2.14e-1)" LIMD1 ENSG00000144791 "LIM domain containing 1" Q9UGP4 3 45555394-45686341 "Plasma proteins, Predicted intracellular proteins" "RNA-mediated gene silencing, Transcription, Transcription regulation" Repressor "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 219.4;Transitional alveolar cells: 179.0;Tuft cells: 184.5" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 136.0;oligodendrocyte precursor cell: 172.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064220, HPA071736" Approved Supported "Nucleoplasm,Focal adhesion sites" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 22 "Nucleoplasm, Focal adhesion sites" "HPA064220: , HPA071736: " "unprognostic (1.77e-2)" "unprognostic (1.15e-1)" "unprognostic (3.04e-3)" "unprognostic (9.32e-3)" "unprognostic (4.32e-2)" "unprognostic (1.01e-1)" "unprognostic (7.04e-2)" "unprognostic (1.05e-1)" "unprognostic (3.53e-3)" "unprognostic (1.94e-3)" "potential prognostic favorable (9.85e-5)" "unprognostic (6.03e-3)" "unprognostic (1.74e-2)" "unprognostic (1.69e-1)" "unprognostic (1.87e-1)" "unprognostic (2.30e-3)" "unprognostic (1.81e-1)" "unprognostic (4.31e-2)" "unprognostic (4.70e-2)" "unprognostic (1.07e-1)" "unprognostic (2.57e-1)" "unprognostic (3.80e-1)" "unprognostic (2.40e-1)" "unprognostic (1.30e-2)" "unprognostic (7.67e-3)" "unprognostic (2.15e-3)" "unprognostic (3.83e-2)" "unprognostic (2.04e-2)" "unprognostic (1.41e-1)" "unprognostic (5.64e-2)" "unprognostic (1.38e-1)" LIMD2 MGC10986 ENSG00000136490 "LIM domain containing 2" Q9BT23 17 63695888-63701172 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 105.8;lymphoid tissue: 207.8" "Cell type enhanced" "Detected in some" "B-cells: 4.2;cDC: 4.1;Gastric chief cells: 2.2;Innate lymphoid cells: 3.2;Kupffer cells: 5.1;Megakaryocyte progenitors: 1.7;Megakaryocyte-Erythroid progenitors: 3.2;monocytes: 4.3;Neutrophils: 6.3;NK-cells: 3.4;Plasma cells: 1.9;T-cells: 2.6;Thymocytes: 2.5" "Cell type enhanced" "Detected in some" "leukocyte: 2.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Leukemia: 136.6;lymphoma: 246.9" "Adipose subcutaneous - T-cells, Breast - T-cells, Liver - Kupffer cells, Prostate - T-cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062432, HPA075172" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 51: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 1 Nucleoplasm Cytosol "HPA062432: , HPA075172: " "unprognostic (5.06e-3)" "unprognostic (6.99e-3)" "unprognostic (5.58e-2)" "unprognostic (1.44e-1)" "unprognostic (4.98e-2)" "unprognostic (1.09e-1)" "unprognostic (7.43e-2)" "unprognostic (9.11e-3)" "potential prognostic favorable (7.56e-4)" "unprognostic (3.20e-2)" "unprognostic (1.30e-3)" "unprognostic (6.28e-2)" "unprognostic (5.37e-2)" "unprognostic (1.00e-1)" "unprognostic (6.22e-2)" "unprognostic (1.74e-2)" "unprognostic (6.64e-2)" "unprognostic (9.30e-2)" "unprognostic (1.16e-1)" "unprognostic (4.42e-3)" "unprognostic (1.37e-1)" "unprognostic (2.42e-2)" "unprognostic (4.50e-2)" "unprognostic (2.56e-2)" "unprognostic (8.17e-2)" "unprognostic (4.39e-2)" "unprognostic (3.79e-3)" "unprognostic (7.23e-2)" "unprognostic (2.62e-1)" "unprognostic (2.82e-2)" "unprognostic (4.55e-2)" LIME1 "dJ583P15.4, FLJ20406, LIME" ENSG00000203896 "Lck interacting transmembrane adaptor 1" Q9H400 20 63736283-63739103 "Predicted intracellular proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 258.7" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 6 "leukocyte: 2.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "gdT-cell: 315.5;MAIT T-cell: 285.7;memory CD4 T-cell: 438.9;memory CD8 T-cell: 412.4;naive CD4 T-cell: 290.2;naive CD8 T-cell: 320.3;plasmacytoid DC: 750.7;T-reg: 691.2" "Group enriched" "Detected in all" 8 "dendritic cells: 750.7;T-cells: 691.2" "Cancer enriched" "Detected in many" 9 "Myeloma: 158.1" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in many" "Not detected" "Not detected" CAB015363 Approved NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 34: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 9: T-cells - Adaptive immunity: Regulation" 38 "CAB015363: " "unprognostic (8.68e-2)" "unprognostic (3.55e-3)" "unprognostic (2.90e-2)" "unprognostic (5.81e-2)" "unprognostic (9.19e-2)" "unprognostic (1.39e-2)" "unprognostic (2.57e-1)" "unprognostic (1.39e-2)" "unprognostic (2.74e-3)" "unprognostic (5.35e-2)" "unprognostic (1.40e-3)" "unprognostic (2.74e-2)" "unprognostic (3.67e-3)" "potential prognostic favorable (1.49e-4)" "unprognostic (9.98e-2)" "unprognostic (5.45e-2)" "unprognostic (1.51e-1)" "unprognostic (1.65e-1)" "potential prognostic favorable (9.75e-4)" "unprognostic (5.56e-2)" "unprognostic (9.93e-2)" "unprognostic (9.18e-2)" "unprognostic (1.95e-1)" "unprognostic (9.68e-3)" "unprognostic (4.20e-3)" "unprognostic (4.27e-1)" "unprognostic (8.38e-2)" "unprognostic (8.68e-2)" "unprognostic (1.53e-1)" LIMK1 LIMK ENSG00000106683 "LIM domain kinase 1" P53667 7 74082933-74122525 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 87.1" "Cell type enhanced" "Detected in many" "Megakaryocytes: 49.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028516, HPA073571" Approved Supported "Nuclear speckles,Cytosol" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 78: Brain - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 39: Non-specific - Transcription" "Cluster 109: Neurons - Neuronal signaling" 22 "Nuclear speckles, Cytosol" "HPA028516: , HPA073571: " "unprognostic (2.77e-1)" "unprognostic (1.33e-1)" "unprognostic (1.43e-2)" "unprognostic (4.20e-2)" "unprognostic (1.02e-2)" "unprognostic (2.09e-1)" "unprognostic (1.89e-2)" "unprognostic (4.32e-2)" "unprognostic (9.64e-2)" "unprognostic (2.15e-2)" "potential prognostic unfavorable (6.17e-6)" "unprognostic (9.86e-3)" "unprognostic (1.75e-2)" "potential prognostic unfavorable (2.70e-5)" "unprognostic (6.50e-3)" "unprognostic (1.56e-2)" "unprognostic (1.54e-2)" "unprognostic (3.79e-2)" "unprognostic (2.99e-1)" "unprognostic (7.32e-2)" "unprognostic (6.95e-3)" "unprognostic (3.05e-2)" "unprognostic (7.89e-2)" "unprognostic (1.20e-1)" "unprognostic (7.52e-2)" "unprognostic (7.78e-2)" "unprognostic (1.64e-2)" "unprognostic (5.50e-2)" "unprognostic (7.73e-2)" "unprognostic (1.71e-1)" "unprognostic (4.77e-1)" LIMK2 ENSG00000182541 "LIM domain kinase 2" P53671 22 31212239-31280080 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 10 "Neutrophils: 3235.3" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 110.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "eosinophil: 40.1;neutrophil: 97.2" "Lineage enriched" "Detected in all" 6 "granulocytes: 97.2" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Spleen - Neutrophils_2, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008183, CAB019313, HPA053882" Approved Supported Nucleoplasm,Cytosol NA Yes "Cluster 21: Neutrophils - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 15 Nucleoplasm Cytosol "CAB019313: , HPA008183: , HPA053882: " "unprognostic (3.01e-2)" "unprognostic (2.74e-1)" "unprognostic (1.16e-1)" "unprognostic (2.20e-3)" "unprognostic (1.24e-1)" "unprognostic (3.21e-2)" "unprognostic (1.30e-1)" "unprognostic (6.57e-2)" "unprognostic (9.90e-2)" "unprognostic (7.21e-2)" "unprognostic (5.09e-3)" "unprognostic (5.03e-3)" "unprognostic (1.25e-2)" "unprognostic (2.51e-2)" "unprognostic (2.49e-2)" "unprognostic (6.83e-2)" "unprognostic (1.23e-1)" "unprognostic (4.51e-2)" "unprognostic (1.05e-1)" "unprognostic (3.01e-1)" "unprognostic (5.68e-3)" "unprognostic (2.07e-1)" "unprognostic (4.47e-1)" "unprognostic (1.52e-1)" "unprognostic (6.99e-2)" "unprognostic (1.57e-1)" "unprognostic (1.39e-1)" "unprognostic (1.68e-1)" "unprognostic (3.53e-1)" "unprognostic (3.49e-3)" "unprognostic (2.16e-1)" LIMS1 "PINCH, PINCH1" ENSG00000169756 "LIM zinc finger domain containing 1" P48059 2 108533671-108687246 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Megakaryocytes: 3795.5;monocytes: 1251.1;Platelets: 4077.6" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 516.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA058455, HPA061230" Approved Approved "Focal adhesion sites,Cytosol" NA NA 20000000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 47: Platelets - Hemostasis" 19 Cytosol "Focal adhesion sites" "HPA058455: , HPA061230: " "unprognostic (1.35e-1)" "unprognostic (1.69e-1)" "unprognostic (1.07e-1)" "unprognostic (3.11e-2)" "unprognostic (2.95e-1)" "potential prognostic unfavorable (7.48e-4)" "unprognostic (2.06e-1)" "potential prognostic unfavorable (1.07e-4)" "unprognostic (1.10e-1)" "unprognostic (2.04e-2)" "unprognostic (1.85e-3)" "unprognostic (4.20e-2)" "unprognostic (1.38e-2)" "unprognostic (6.94e-3)" "unprognostic (2.51e-2)" "unprognostic (3.30e-2)" "unprognostic (3.82e-3)" "unprognostic (4.62e-2)" "unprognostic (1.07e-1)" "unprognostic (9.07e-2)" "unprognostic (3.59e-3)" "unprognostic (1.38e-2)" "unprognostic (6.76e-3)" "unprognostic (8.61e-2)" "unprognostic (3.55e-1)" "unprognostic (3.06e-2)" "unprognostic (1.63e-1)" "unprognostic (2.59e-2)" "unprognostic (2.17e-1)" "unprognostic (2.24e-2)" "unprognostic (5.07e-2)" LIMS2 "PINCH-2, PINCH2" ENSG00000072163 "LIM zinc finger domain containing 2" Q7Z4I7 2 127638381-127681786 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 473.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 66.1;Breast myoepithelial cells: 54.2;Cardiomyocytes: 105.6;Granulosa cells: 103.8;Hepatic stellate cells: 90.4;Lymphatic endothelial cells: 60.4;Peritubular myoid cells: 53.1;Podocytes: 104.0;Salivary myoepithelial cells: 58.8;Smooth muscle cells: 212.5;Vascular endothelial cells: 199.9;Vascular smooth muscle cells: 113.7" "Cell type enhanced" "Detected in many" "endothelial cell: 308.4;vascular associated smooth muscle cell: 125.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 22.6" "Group enriched" "Detected in many" 13 "B-cells: 22.6;T-cells: 10.7" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 20.6" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058340 Enhanced Supported "Focal adhesion sites" NA NA "Cluster 18: Non-specific - Translation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 47: Endothelial cells - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 4 "Focal adhesion sites" "HPA058340: " "unprognostic (3.25e-2)" "unprognostic (4.94e-2)" "unprognostic (8.51e-2)" "unprognostic (2.70e-2)" "unprognostic (6.56e-2)" "unprognostic (1.62e-1)" "unprognostic (8.38e-2)" "unprognostic (7.75e-2)" "unprognostic (5.67e-2)" "unprognostic (1.07e-1)" "potential prognostic favorable (4.70e-5)" "unprognostic (1.73e-3)" "unprognostic (1.35e-1)" "validated prognostic favorable (1.58e-5)" "validated prognostic favorable (2.81e-7)" "unprognostic (7.08e-2)" "unprognostic (3.29e-1)" "unprognostic (4.01e-2)" "unprognostic (2.19e-1)" "unprognostic (2.26e-2)" "unprognostic (4.03e-2)" "unprognostic (1.87e-2)" "unprognostic (2.72e-1)" "unprognostic (9.19e-3)" "unprognostic (1.41e-1)" "unprognostic (2.27e-2)" "unprognostic (2.49e-1)" "unprognostic (4.87e-3)" "unprognostic (1.92e-1)" "unprognostic (6.33e-2)" "unprognostic (2.29e-1)" LIMS3 ENSG00000256977 "LIM zinc finger domain containing 3" P0CW19 2 109898428-109925625 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "blood vessel: 7.1" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 5.2" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 5 "eosinophil: 1.4" "Lineage enriched" "Detected in single" 14 "granulocytes: 1.4" "Cancer enhanced" "Detected in some" "ovarian cancer: 3.1;Uterine cancer: 3.1" HPA058455 Uncertain Approved "Focal adhesion sites,Cytosol" NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 11: White matter - Signal transduction" "Cluster 71: Lymphoma - Inflammatory response" Cytosol "Focal adhesion sites" "HPA058455: " "unprognostic (2.80e-1)" "unprognostic (1.26e-1)" "unprognostic (4.09e-1)" "unprognostic (3.42e-1)" "unprognostic (8.67e-2)" "unprognostic (2.10e-2)" "unprognostic (7.78e-2)" "potential prognostic unfavorable (3.98e-4)" "unprognostic (2.05e-1)" "unprognostic (2.49e-1)" "unprognostic (1.74e-1)" "unprognostic (3.50e-2)" "unprognostic (2.37e-1)" LIMS4 LIMS3L ENSG00000256671 "LIM zinc finger domain containing 4" P0CW20 2 110445883-110473075 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 8.0" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 12 "Kidney Chromophobe (TCGA): 1.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "basophil: 4.0" "Lineage enriched" "Detected in single" 9 "granulocytes: 4.0" "Low cancer specificity" "Detected in single" HPA058455 Uncertain Uncertain "Focal adhesion sites,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 6: Non-specific - Immune response" "Cluster 2: Mucus-secreting cells - Unknown function" 8 Cytosol "Focal adhesion sites" "HPA058455: " "unprognostic (2.15e-2)" "unprognostic (1.29e-1)" "unprognostic (1.17e-1)" LIN28A "CSDD1, FLJ12457, LIN-28, LIN28, ZCCHC1" ENSG00000131914 "Lin-28 homolog A" Q9H9Z2 1 26410817-26429728 "Predicted intracellular proteins" "RNA-mediated gene silencing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 14 "testis: 4.9" "Cell type enriched" "Detected in some" 4 "Late spermatids: 111.0" "Cell type enhanced" "Detected in single" "midbrain-derived inhibitory: 1.2" "Cancer enriched" "Detected in some" 85 "Testicular Germ Cell Tumor (TCGA): 334.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 10 "testis cancer: 277.3" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB020785, HPA063074, HPA068814" Enhanced Supported "Nucleoli,Cytosol,Rods & Rings" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 48: Non-specific - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 250 Cytosol "Nucleoli, Rods & Rings" "CAB020785: , HPA063074: , HPA068814: " "unprognostic (1.82e-2)" "unprognostic (2.33e-1)" "unprognostic (8.97e-2)" "unprognostic (3.69e-2)" "unprognostic (1.04e-1)" LIN28B "CSDD2, FLJ16517" ENSG00000187772 "Lin-28 homolog B" Q6ZN17 6 104936616-105083332 "Predicted intracellular proteins" "RNA-mediated gene silencing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "placenta: 61.5" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 68.3;Corticotrophs: 69.0;Cytotrophoblasts: 241.4;Extravillous trophoblasts: 287.0;Late spermatids: 45.2;Migrating cytotrophoblasts: 218.7;Retinal ganglion cells: 119.7;Syncytiotrophoblasts: 140.7;Undifferentiated spermatogonia: 45.1" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in single" 24 "Testicular Germ Cell Tumor (TCGA): 21.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 22.1;testis cancer: 41.0" "Pituitary gland - Corticotropes, Testis - Early spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA036630, HPA061745" Enhanced Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 34: Testis cancer - Unknown function" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 17 "Nucleoplasm, Nucleoli" Cytosol "HPA036630: , HPA061745: " "unprognostic (2.97e-1)" "unprognostic (2.42e-2)" "unprognostic (5.59e-2)" LIN37 "F25965, lin-37, ZK418.4" ENSG00000267796 "Lin-37 DREAM MuvB core complex component" Q96GY3 19 35748361-35754519 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in single" "Foveolar cells: 1.0" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043253, HPA047809" Uncertain Supported Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 70: Intestinal goblet cells - Mucin production" 47 Nucleoplasm "HPA043253: , HPA047809: " "unprognostic (1.94e-1)" "unprognostic (2.37e-1)" "unprognostic (4.09e-1)" "unprognostic (3.12e-2)" "unprognostic (1.90e-2)" "unprognostic (2.47e-1)" "unprognostic (4.09e-2)" "unprognostic (5.73e-2)" "unprognostic (6.62e-2)" "potential prognostic unfavorable (6.99e-4)" "unprognostic (2.21e-1)" "unprognostic (1.59e-1)" "unprognostic (3.19e-1)" "unprognostic (3.35e-3)" "unprognostic (5.79e-2)" "unprognostic (5.73e-2)" "unprognostic (2.43e-2)" "unprognostic (1.97e-1)" "unprognostic (1.67e-1)" "unprognostic (4.67e-2)" "unprognostic (2.67e-2)" "unprognostic (1.02e-3)" "unprognostic (2.42e-2)" "unprognostic (2.33e-2)" "unprognostic (5.80e-2)" "unprognostic (4.62e-1)" "unprognostic (2.64e-1)" "unprognostic (1.46e-1)" "unprognostic (1.17e-1)" "unprognostic (1.33e-1)" "unprognostic (1.48e-1)" LIN52 C14orf46 ENSG00000205659 "Lin-52 DREAM MuvB core complex component" 14 74084956-74201493 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 213.1;Proximal tubule cells: 333.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000900, HPA001777" Uncertain Approved "Nuclear speckles" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 36: Brain & Liver - Signaling" "Cluster 1: Neurons - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 88: Proximal tubular cells - Transmembrane transport" 10 "Nuclear speckles" "HPA000900: , HPA001777: " "unprognostic (1.50e-2)" "unprognostic (1.57e-1)" "unprognostic (2.42e-3)" "unprognostic (1.58e-1)" "unprognostic (4.60e-2)" "unprognostic (3.81e-2)" "unprognostic (3.25e-2)" "unprognostic (1.28e-2)" "unprognostic (2.37e-3)" "unprognostic (6.87e-2)" "validated prognostic favorable (6.03e-5)" "validated prognostic favorable (1.29e-4)" "unprognostic (9.75e-2)" "potential prognostic unfavorable (9.92e-6)" "unprognostic (6.91e-2)" "unprognostic (2.21e-1)" "unprognostic (3.48e-2)" "unprognostic (6.73e-3)" "unprognostic (2.85e-1)" "unprognostic (8.06e-2)" "unprognostic (2.48e-1)" "unprognostic (1.76e-3)" "potential prognostic unfavorable (5.06e-4)" "unprognostic (2.75e-1)" "unprognostic (1.70e-1)" "unprognostic (2.00e-1)" "unprognostic (9.21e-3)" "unprognostic (2.06e-1)" "unprognostic (3.58e-2)" "unprognostic (2.71e-2)" "unprognostic (3.21e-1)" LIN54 "CXCDC1, DKFZp686L1814, JC8.6, MIP120, TCX1" ENSG00000189308 "Lin-54 DREAM MuvB core complex component" Q6MZP7 4 82909973-83012926 "Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 122.1;Monocyte progenitors: 132.4;Neutrophil progenitors: 191.4;Neutrophils: 194.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056606 Approved NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 27 "HPA056606: " "unprognostic (1.23e-1)" "unprognostic (7.65e-3)" "unprognostic (4.62e-3)" "unprognostic (4.36e-2)" "unprognostic (1.71e-1)" "potential prognostic unfavorable (1.86e-4)" "unprognostic (1.83e-1)" "unprognostic (1.27e-1)" "unprognostic (2.81e-2)" "unprognostic (1.36e-3)" "validated prognostic favorable (2.26e-8)" "validated prognostic favorable (6.00e-5)" "unprognostic (1.39e-1)" "unprognostic (5.70e-3)" "unprognostic (1.44e-1)" "potential prognostic unfavorable (4.12e-4)" "unprognostic (2.38e-2)" "unprognostic (5.59e-2)" "unprognostic (4.50e-2)" "unprognostic (1.56e-1)" "unprognostic (1.25e-2)" "unprognostic (1.35e-2)" "unprognostic (2.64e-2)" "unprognostic (2.73e-2)" "unprognostic (9.38e-3)" "unprognostic (1.40e-1)" "unprognostic (2.40e-2)" "unprognostic (3.89e-2)" "unprognostic (1.74e-1)" "unprognostic (5.96e-2)" "unprognostic (2.72e-1)" LIN7A "LIN-7A, MALS-1, TIP-33, VELI1" ENSG00000111052 "Lin-7 homolog A, crumbs cell polarity complex component" O14910 12 80792520-80937934 "Predicted intracellular proteins" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 26.3;retina: 24.6" "Cell type enhanced" "Detected in many" "Bergmann glia: 257.8;Lactotrophs: 237.1;Late primary spermatocytes: 198.9;Neutrophil progenitors: 687.2;Neutrophils: 714.1;Renal collecting duct intercalated cells: 253.2;Retinal bipolar cells: 290.1;Thyrotrophs: 171.9" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 44.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 18.9;eosinophil: 15.8;neutrophil: 30.1" "Lineage enriched" "Detected in many" 6 "granulocytes: 30.1" "Cancer enhanced" "Detected in many" "Bone cancer: 9.1" "Prostate - Fibroblasts, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071562 Approved NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 2: Neurons - Nucleosome" "Cluster 59: Leukemia - T-cell receptor" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 32 "HPA071562: " "unprognostic (4.00e-2)" "unprognostic (4.37e-2)" "unprognostic (2.38e-1)" "unprognostic (3.06e-1)" "unprognostic (2.08e-1)" "unprognostic (2.71e-2)" "unprognostic (2.50e-1)" "unprognostic (7.97e-3)" "validated prognostic favorable (5.31e-9)" "validated prognostic favorable (2.84e-4)" "unprognostic (6.40e-2)" "unprognostic (6.85e-2)" "unprognostic (8.80e-2)" "unprognostic (2.45e-2)" "unprognostic (1.40e-2)" "unprognostic (1.58e-2)" "unprognostic (2.21e-2)" "unprognostic (1.29e-1)" "potential prognostic unfavorable (5.46e-4)" "unprognostic (3.92e-1)" "unprognostic (5.71e-2)" "unprognostic (9.34e-2)" "potential prognostic unfavorable (7.81e-5)" "unprognostic (2.45e-2)" "unprognostic (1.62e-1)" LIN7B "LIN-7B, MALS-2, VELI2" ENSG00000104863 "Lin-7 homolog B, crumbs cell polarity complex component" Q9HAP6 19 49114324-49118460 "Predicted intracellular proteins" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 51.4;skeletal muscle: 50.4" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 61.1;Esophageal apical cells: 103.1;Oocytes: 64.5;Undifferentiated spermatogonia: 108.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Pituitary gland - Lactotropes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 1: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 34 "unprognostic (5.20e-2)" "unprognostic (1.21e-1)" "unprognostic (2.06e-1)" "unprognostic (1.34e-2)" "unprognostic (2.68e-2)" "unprognostic (3.73e-1)" "unprognostic (2.38e-1)" "unprognostic (3.40e-1)" "unprognostic (3.40e-2)" "unprognostic (2.26e-1)" "unprognostic (7.11e-2)" "unprognostic (8.76e-3)" "unprognostic (1.65e-1)" "unprognostic (1.78e-2)" "unprognostic (3.71e-2)" "unprognostic (4.18e-3)" "unprognostic (4.64e-2)" "unprognostic (9.52e-3)" "unprognostic (3.08e-1)" "unprognostic (1.55e-1)" "unprognostic (7.42e-2)" "unprognostic (1.09e-3)" "unprognostic (9.70e-3)" "unprognostic (1.70e-1)" "unprognostic (9.68e-2)" "unprognostic (5.54e-2)" "unprognostic (5.86e-2)" "unprognostic (2.35e-2)" "unprognostic (2.14e-1)" "unprognostic (1.53e-1)" "unprognostic (9.48e-2)" LIN7C "FLJ11215, LIN-7-C, LIN-7C, MALS-3, VELI3" ENSG00000148943 "Lin-7 homolog C, crumbs cell polarity complex component" Q9NUP9 11 27494418-27506769 "Predicted intracellular proteins" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051118 Approved NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 76: Non-specific - Metabolism" "Cluster 2: Neurons - Nucleosome" "Cluster 24: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 44 "HPA051118: " "unprognostic (3.01e-3)" "unprognostic (3.93e-2)" "unprognostic (3.62e-1)" "unprognostic (8.13e-2)" "unprognostic (2.91e-1)" "unprognostic (1.40e-1)" "unprognostic (1.89e-1)" "unprognostic (1.97e-1)" "unprognostic (2.11e-1)" "unprognostic (2.21e-2)" "validated prognostic favorable (1.14e-6)" "validated prognostic favorable (2.35e-4)" "unprognostic (1.11e-2)" "unprognostic (1.36e-1)" "unprognostic (6.80e-2)" "unprognostic (4.19e-2)" "potential prognostic favorable (6.67e-4)" "unprognostic (6.57e-2)" "unprognostic (1.36e-1)" "unprognostic (1.41e-1)" "unprognostic (1.22e-1)" "unprognostic (5.72e-2)" "unprognostic (2.52e-2)" "unprognostic (5.32e-2)" "unprognostic (3.40e-2)" "unprognostic (4.92e-2)" "unprognostic (6.78e-2)" "unprognostic (7.52e-2)" "unprognostic (1.72e-1)" "unprognostic (1.38e-1)" "unprognostic (8.33e-2)" LIN9 TGS ENSG00000183814 "Lin-9 DREAM MuvB core complex component" Q5TKA1 1 226231149-226309869 "Essential proteins, Predicted intracellular proteins" "Cell cycle, DNA synthesis" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 91.6;Differentiating spermatogonia: 47.8;Early primary spermatocytes: 72.4;Erythrocyte progenitors: 65.5;Undifferentiated spermatogonia: 48.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skin - Mitotic cells (Skin), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030241 Uncertain Supported Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 2: Neurons - Nucleosome" "Cluster 45: Non-specific - Nuclear processes" "Cluster 27: Non-specific - Cell proliferation" 25 Nucleoplasm "HPA030241: " "unprognostic (3.88e-1)" "unprognostic (1.83e-1)" "unprognostic (4.74e-2)" "unprognostic (6.34e-3)" "unprognostic (9.54e-2)" "unprognostic (5.07e-2)" "unprognostic (2.83e-2)" "unprognostic (3.45e-2)" "unprognostic (2.20e-2)" "unprognostic (1.33e-3)" "unprognostic (3.01e-3)" "unprognostic (5.19e-1)" "unprognostic (1.16e-2)" "potential prognostic unfavorable (1.14e-4)" "unprognostic (5.41e-3)" "unprognostic (1.43e-3)" "unprognostic (1.35e-2)" "unprognostic (1.75e-2)" "unprognostic (6.92e-2)" "unprognostic (6.63e-2)" "unprognostic (2.74e-2)" "unprognostic (4.48e-3)" "unprognostic (1.65e-2)" "unprognostic (3.07e-1)" "unprognostic (1.32e-1)" "unprognostic (9.58e-2)" "unprognostic (3.08e-3)" "unprognostic (7.49e-2)" "unprognostic (6.72e-2)" "unprognostic (1.39e-1)" "unprognostic (6.95e-2)" LINC00672 ENSG00000263874 "Long intergenic non-protein coding RNA 672" 17 38925168-38929384 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 13.7" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 18.4;Brain inhibitory neurons: 17.9;Hepatic stellate cells: 25.8;Neutrophils: 26.2;Other brain neurons: 25.2;Retinal amacrine cells: 15.4;Retinal bipolar cells: 29.3;Retinal horizontal cells: 18.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Fibroblasts" "Low region specificity" "Detected in all" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 1: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 24: Neutrophils - Innate immunity signal integration" "unprognostic (5.99e-2)" "unprognostic (1.23e-1)" "unprognostic (2.30e-2)" "unprognostic (9.07e-3)" "unprognostic (1.44e-1)" "unprognostic (1.78e-1)" "unprognostic (2.99e-2)" "unprognostic (7.27e-2)" "unprognostic (4.89e-2)" "unprognostic (2.36e-2)" "unprognostic (1.51e-1)" "unprognostic (2.80e-3)" LINC02203 ENSG00000280709 "Long intergenic non-protein coding RNA 2203" 15 21552795-21653276 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 19 "testis: 5.5" "Group enriched" "Detected in some" 10 "Early spermatids: 21.5;Late primary spermatocytes: 8.9;Late spermatids: 8.8" "Cell type enhanced" "Detected in some" "CGE interneuron: 1.9;deep-layer near-projecting: 1.7;oligodendrocyte precursor cell: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA057442 Uncertain Approved Centrosome NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" Centrosome "HPA057442: " LINC02210-CRHR1 ENSG00000263715 "LINC02210-CRHR1 readthrough" 17 45620344-45835826 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 8 "brain: 2.1" "Group enriched" "Detected in some" 14 "Distal convoluted tubule cells: 30.8;Loop of henle epithelial cells: 23.8;Papillary tip epithelial cells: 20.8;Podocytes: 29.7;Proximal tubule cells: 14.0;Renal collecting duct intercalated cells: 19.0;Renal collecting duct principal cells: 20.8;Renal connecting tubule cells: 24.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 105: Non-specific - Mixed function" LINC02218 ENSG00000249662 "Long intergenic non-protein coding RNA 2218" 5 17444010-17486829 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Müller glia: 12.7;Neutrophils: 25.3;Retinal amacrine cells: 18.4;Retinal ganglion cells: 11.6" "Group enriched" "Detected in some" 11 "deep-layer corticothalamic and 6b: 24.0;deep-layer near-projecting: 67.9" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 87 "neutrophil: 8.6" "Lineage enriched" "Detected in single" 87 "granulocytes: 8.6" "Not detected" "Not detected" NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" LINGO1 "FLJ14594, LERN1, LRRN6A" ENSG00000169783 "Leucine rich repeat and Ig domain containing 1" Q96FE5 15 77613027-77820900 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 109.9" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 244.0;Esophageal apical cells: 382.1;Foveolar cells: 346.1;Late spermatids: 288.7;Loop of henle epithelial cells: 270.9;Mucous neck cells: 269.6;Papillary tip epithelial cells: 302.6;Podocytes: 287.3;Proximal tubule cells: 281.4;Renal collecting duct intercalated cells: 239.2;Renal collecting duct principal cells: 305.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 45.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 65.3" "Skin - Inner root sheath cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074653 Enhanced Supported "Plasma membrane" NA NA 10000 "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 67: Plasma cells - Plasma cell differentiation" 12 "Plasma membrane" "HPA074653: " "unprognostic (3.02e-1)" "unprognostic (9.16e-2)" "unprognostic (7.64e-2)" "unprognostic (4.52e-2)" "unprognostic (9.97e-2)" "unprognostic (6.54e-2)" "unprognostic (2.06e-1)" "unprognostic (1.57e-3)" "unprognostic (2.60e-1)" "unprognostic (1.38e-1)" "unprognostic (1.01e-1)" "potential prognostic favorable (3.55e-4)" "potential prognostic unfavorable (1.96e-5)" "unprognostic (4.98e-2)" "unprognostic (1.48e-1)" "unprognostic (5.65e-2)" "unprognostic (3.58e-2)" "unprognostic (1.27e-1)" "potential prognostic favorable (5.29e-4)" "unprognostic (2.07e-1)" "unprognostic (9.24e-2)" "unprognostic (1.34e-1)" "unprognostic (5.20e-2)" "unprognostic (5.22e-2)" "unprognostic (5.95e-2)" "unprognostic (6.60e-2)" "unprognostic (1.04e-1)" "unprognostic (8.59e-2)" "unprognostic (2.88e-1)" "unprognostic (1.38e-2)" "unprognostic (2.30e-1)" LINGO2 "LERN3, LRRN6C" ENSG00000174482 "Leucine rich repeat and Ig domain containing 2" Q7L985 9 27937617-29213601 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "endometrium 1: 7.3;smooth muscle: 8.2" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 851.0;Brain excitatory neurons: 808.5;Brain inhibitory neurons: 862.6;Decidual stromal cells: 463.6;Endometrial stromal cells: 495.0;Gonadotrophs: 439.7;Hematopoietic stem cells: 483.3;NK-cells: 406.2;Other brain neurons: 722.3;Pancreatic islet cells: 684.8;Retinal amacrine cells: 388.7;Retinal bipolar cells: 886.9;Retinal ganglion cells: 803.5" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in single" "Skin Cutaneous Melanoma (TCGA): 1.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "NK-cell: 1.3" "Lineage enriched" "Detected in single" 8 "NK-cells: 1.3" "Cancer enhanced" "Detected in some" "Neuroblastoma: 11.9" "Adrenal gland - Adrenal medulla cells, Pancreas - Alpha cells, Pancreas - Beta cells, Pituitary gland - Corticotropes, Prostate - Fibroblasts, Spleen - NK-cells (Spleen), Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA016633, CAB025361" Approved Approved "Nucleoplasm,Cytoplasmic bodies" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 65: Brain - Transcription" "Cluster 53: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 4 "Cytoplasmic bodies" Nucleoplasm "CAB025361: , HPA016633: " "unprognostic (2.54e-1)" "unprognostic (1.18e-1)" "unprognostic (6.51e-3)" LINGO3 "LERN2, LRRN6B" ENSG00000220008 "Leucine rich repeat and Ig domain containing 3" P0C6S8 19 2287164-2308154 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 23.5;lymphoid tissue: 6.0" "Cell type enhanced" "Detected in many" "B-cells: 80.8;Breast myoepithelial cells: 43.9;cDC: 34.5;Decidual stromal cells: 41.0;Neutrophils: 68.6;Retinal bipolar cells: 167.5;Thymocytes: 61.0" "Cell type enhanced" "Detected in many" "medium spiny neuron: 10.3;oligodendrocyte precursor cell: 17.3" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 2.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 1.3;eosinophil: 4.0;neutrophil: 1.5" "Lineage enriched" "Detected in single" 9 "granulocytes: 4.0" "Cancer enriched" "Detected in some" 5 "Leukemia: 8.1" "Adrenal gland - Macrophages, Minor Salivary Gland - Macrophages" "Region enhanced" "Detected in all" "basal ganglia: 59.6" "Group enriched" "Detected in many" 8 "basal ganglia: 38.0;cerebellum: 26.2;hippocampal formation: 11.0" "HPA043781, HPA059558" Enhanced Approved Mitochondria NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 20: Non-specific - Transcription regulation" Mitochondria "HPA043781: , HPA059558: " "unprognostic (1.93e-1)" "unprognostic (2.45e-1)" "unprognostic (9.74e-2)" "unprognostic (4.04e-3)" "unprognostic (3.17e-1)" LINGO4 LRRN6D ENSG00000213171 "Leucine rich repeat and Ig domain containing 4" Q6UY18 1 151800264-151805419 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 6.3;skeletal muscle: 22.7" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 10.6;Epicardial cells: 2.3;Fallopian tube ciliated cells: 1.7;Innate lymphoid cells: 6.2;Myonuclei: 3.6;Renal collecting duct intercalated cells: 1.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Neuroblastoma: 1.0" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Heart muscle - Cardiomyocytes" "Group enriched" "Detected in many" 4 "cerebellum: 1.8;hypothalamus: 1.0;midbrain: 2.7;pons and medulla: 4.0;thalamus: 1.4" "Region enriched" "Detected in many" 7 "spinal cord: 25.8" HPA060781 Uncertain Uncertain "Golgi apparatus,Vesicles" NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 25: Non-specific - Transcription" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" "Golgi apparatus, Vesicles" "HPA060781: " "unprognostic (9.02e-2)" "potential prognostic favorable (3.20e-5)" "unprognostic (3.99e-2)" LINS1 "LINS, MRT27, WINS1" ENSG00000140471 "Lines homolog 1" Q8NG48 15 100559369-100603230 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038578, HPA038579" Approved Approved Nucleoplasm NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 61: Non-specific - Transcription" "Cluster 9: Non-specific - Receptor signaling" "Cluster 58: Non-specific - Nuclear processes" "Cluster 9: T-cells - Adaptive immunity: Regulation" 3 Nucleoplasm "HPA038578: , HPA038579: " "unprognostic (4.44e-2)" "unprognostic (1.55e-1)" "unprognostic (1.59e-1)" "unprognostic (1.88e-2)" "unprognostic (1.57e-1)" "unprognostic (1.94e-1)" "unprognostic (1.92e-1)" "unprognostic (1.39e-2)" "unprognostic (9.00e-2)" "unprognostic (3.24e-3)" "potential prognostic favorable (1.35e-5)" "unprognostic (1.25e-2)" "unprognostic (5.46e-2)" "unprognostic (2.03e-1)" "unprognostic (2.73e-1)" "unprognostic (1.37e-1)" "unprognostic (4.19e-2)" "unprognostic (3.43e-2)" "unprognostic (1.83e-1)" "unprognostic (8.30e-2)" "unprognostic (4.01e-2)" "unprognostic (1.15e-2)" "unprognostic (1.04e-2)" "unprognostic (1.74e-1)" "unprognostic (1.23e-1)" "potential prognostic unfavorable (1.21e-4)" "unprognostic (2.14e-1)" "unprognostic (1.55e-1)" "unprognostic (1.55e-1)" "unprognostic (4.63e-2)" LIPA "CESD, LAL" ENSG00000107798 "Lipase A, lysosomal acid type" P38571 10 89213569-89414557 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 375.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 319.2;Kupffer cells: 1525.1;Macrophages: 360.9;Oligodendrocytes: 407.0" "Cell type enhanced" "Detected in all" "oligodendrocyte: 564.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 167.7;intermediate monocyte: 355.8;myeloid DC: 123.8;non-classical monocyte: 199.7" "Group enriched" "Detected in all" 6 "dendritic cells: 123.8;monocytes: 355.8" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Lung - Macrophages, Minor Salivary Gland - Macrophages, Skeletal muscle - Endothelial cells, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034892, HPA057052" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol" "Intracellular and membrane" Enzyme NA NA 330000 "Cluster 40: Monocytes - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 30: White matter - Myelination" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 1 "Vesicles, Cytosol" "Nucleoplasm, Nucleoli fibrillar center" "CAB034892: , HPA057052: " "unprognostic (2.69e-1)" "unprognostic (1.65e-2)" "unprognostic (2.33e-2)" "unprognostic (1.54e-1)" "unprognostic (3.46e-1)" "unprognostic (3.73e-2)" "unprognostic (1.21e-1)" "unprognostic (9.04e-2)" "unprognostic (2.22e-2)" "unprognostic (9.56e-2)" "potential prognostic favorable (6.59e-9)" "unprognostic (3.22e-2)" "unprognostic (5.76e-2)" "unprognostic (1.16e-1)" "unprognostic (3.71e-2)" "unprognostic (5.78e-2)" "unprognostic (3.41e-2)" "unprognostic (3.49e-2)" "unprognostic (1.72e-2)" "unprognostic (1.06e-1)" "unprognostic (3.60e-2)" "unprognostic (3.02e-1)" "unprognostic (2.98e-1)" "unprognostic (3.44e-2)" "unprognostic (6.16e-2)" "unprognostic (4.49e-2)" "unprognostic (1.20e-1)" "unprognostic (2.19e-2)" "unprognostic (4.79e-2)" "unprognostic (3.56e-1)" "unprognostic (6.06e-2)" LIPC "HL, HTGL" ENSG00000166035 "Lipase C, hepatic type" P11150 15 58410569-58569844 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" "Heparin-binding, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 28 "liver: 159.9" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 36.8;Hepatocytes: 302.8;Loop of henle epithelial cells: 48.1;Microglia: 70.1;Papillary tip epithelial cells: 88.5;Pituitary stem cells: 34.8;Renal collecting duct principal cells: 76.9;Renal connecting tubule cells: 43.3" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 83.7;oligodendrocyte: 29.0" "Group enriched" "Detected in many" 18 "Kidney Renal Clear Cell Carcinoma (TCGA): 21.0;Kidney Renal Papillary Cell Carcinoma (TCGA): 73.6;Liver Hepatocellular Carcinoma (TCGA): 66.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 7 "granulocytes: 1.7;NK-cells: 1.5;T-cells: 1.8" "Group enriched" "Detected in many" 5 "Gastric cancer: 22.7;Kidney cancer: 6.3;liver cancer: 18.6" "Adipose subcutaneous - Adipose progenitor cells, Liver - Hepatocytes, Minor Salivary Gland - Fibroblasts, Pituitary gland - Gonadotropes, Prostate - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to blood" Enzyme NA NA 13000000 "Cluster 33: Non-specific - ATP binding" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 37: Neurons - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 93: Hepatocytes - Bile production & excretion" "unprognostic (6.99e-2)" "unprognostic (4.39e-2)" "unprognostic (3.24e-1)" "unprognostic (6.30e-2)" "unprognostic (7.22e-2)" "unprognostic (4.82e-3)" "unprognostic (1.22e-1)" "unprognostic (6.39e-2)" "unprognostic (1.55e-2)" "unprognostic (1.16e-1)" "unprognostic (3.13e-1)" "unprognostic (1.98e-1)" "unprognostic (8.49e-2)" "unprognostic (1.75e-1)" "unprognostic (4.09e-2)" LIPE HSL ENSG00000079435 "Lipase E, hormone sensitive type" Q05469 19 42401514-42427388 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Lipid degradation, Lipid metabolism, Steroid metabolism, Sterol metabolism" Hydrolase "Diabetes mellitus, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "adipose tissue: 783.5;breast: 523.8" "Group enriched" "Detected in many" 5 "Adipocytes: 452.0;Early spermatids: 179.4;Late spermatids: 403.3" "Cell type enhanced" "Detected in all" "oligodendrocyte: 80.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Minor Salivary Gland - Adipocytes (Minor salivary gland), Skin - Adipocytes (Skin), Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006567, CAB017700" Enhanced Supported Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 30: White matter - Myelination" "Cluster 55: Lymphoma - Immune response" "Cluster 89: Adipocytes - Lipid metabolism" 6 Cytosol "CAB017700: , HPA006567: " "unprognostic (9.84e-2)" "unprognostic (2.11e-2)" "unprognostic (2.25e-2)" "unprognostic (1.52e-1)" "unprognostic (1.13e-1)" "unprognostic (2.31e-1)" "unprognostic (2.90e-1)" "unprognostic (6.22e-2)" "potential prognostic favorable (1.04e-4)" "unprognostic (3.22e-1)" "validated prognostic favorable (9.48e-5)" "validated prognostic favorable (4.01e-5)" "unprognostic (1.35e-1)" "unprognostic (1.39e-2)" "unprognostic (1.57e-1)" "unprognostic (5.91e-2)" "unprognostic (3.64e-1)" "unprognostic (3.52e-2)" "unprognostic (1.71e-1)" "unprognostic (2.06e-3)" "potential prognostic favorable (3.79e-4)" "unprognostic (2.49e-1)" "unprognostic (3.13e-1)" "unprognostic (7.93e-2)" "unprognostic (9.68e-3)" "unprognostic (1.23e-1)" "unprognostic (1.23e-1)" "unprognostic (1.23e-1)" "unprognostic (2.45e-1)" "unprognostic (1.52e-1)" LIPF "HGL, HLAL" ENSG00000182333 "Lipase F, gastric type" P07098 10 88664441-88678814 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 143 "stomach 1: 35389.5" "Cell type enhanced" "Detected in some" "Gastric chief cells: 139374.4;Mucous neck cells: 29153.1;Parietal cells: 42346.5" "Cell type enriched" "Detected in single" 28 "ependymal cell: 6.1" "Cancer enriched" "Detected in some" 59 "Stomach Adenocarcinoma (TCGA): 595.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Stomach - Chief cells" "Region enriched" "Detected in single" 77 "olfactory bulb: 7.6" HPA045930 Enhanced "Secreted to digestive system" Enzyme NA NA "Cluster 60: Stomach - Digestion" "Cluster 27: Breast cancer - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 1 "HPA045930: " "unprognostic (2.52e-1)" LIPG EDL ENSG00000101670 "Lipase G, endothelial type" Q9Y5X9 18 49560699-49599185 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" "Heparin-binding, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "placenta: 140.4;thyroid gland: 226.7" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 161.5;Endometrial glandular cells: 75.9;Endometrial luminal cells: 118.8;Extravillous trophoblasts: 145.4;Hepatocytes: 120.2;Retinal pigment epithelial cells: 98.0;Tuft cells: 161.4;Urothelial cells: 84.7" "Group enriched" "Detected in many" 6 "central nervous system macrophage: 38.0;cerebellar inhibitory: 103.6" "Cancer enriched" "Detected in many" 5 "Thyroid Carcinoma (TCGA): 73.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Stomach - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA016966 Uncertain "Secreted to blood" Enzyme NA NA 657000000 760000 "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 44: Non-specific - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 51: Secretory epithelial cells - Mixed function" 29 "HPA016966: " "unprognostic (9.89e-3)" "unprognostic (2.66e-2)" "unprognostic (6.48e-2)" "unprognostic (1.11e-3)" "unprognostic (1.18e-1)" "unprognostic (2.23e-2)" "unprognostic (9.27e-2)" "unprognostic (4.47e-3)" "unprognostic (3.55e-1)" "unprognostic (1.85e-2)" "unprognostic (1.53e-1)" "unprognostic (3.55e-2)" "unprognostic (3.04e-1)" "unprognostic (1.32e-1)" "unprognostic (3.22e-1)" "unprognostic (5.44e-2)" "unprognostic (2.47e-2)" "unprognostic (6.76e-3)" "unprognostic (6.00e-3)" "unprognostic (2.95e-1)" "unprognostic (4.53e-2)" "unprognostic (4.06e-2)" "unprognostic (7.25e-2)" "unprognostic (1.02e-1)" "unprognostic (2.59e-2)" "unprognostic (4.44e-1)" "unprognostic (1.41e-2)" "unprognostic (6.46e-2)" "unprognostic (4.74e-2)" "unprognostic (3.53e-1)" LIPH "LPDLR, mPA-PLA1, mPA-PLA1alpha, PLA1B" ENSG00000163898 "Lipase H" Q8WWY8 3 185506262-185552588 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" "Heparin-binding, Hydrolase" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 35.4;stomach 1: 45.5" "Cell type enhanced" "Detected in many" "Colonocytes: 638.9;Enterocytes: 641.7;Esophageal apical cells: 449.3;Foveolar cells: 1572.1;Goblet cells: 561.2;Ocular epithelial cells: 383.3;Prostatic hillock cells: 320.9;Urothelial cells: 1156.9" "Group enriched" "Detected in many" 4 "choroid plexus epithelial cell: 50.4;deep-layer corticothalamic and 6b: 17.2" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "choroid plexus: 16.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 39.7;pancreatic cancer: 33.3" "Colon - Colon enterocytes, Liver - Cholangiocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Ductal cells, Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" HPA049079 Approved "Secreted to blood" Enzyme NA NA "Cluster 17: Intestine - Digestion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 68: Foveolar cells - Mucosal defense" 1 "HPA049079: " "unprognostic (6.27e-3)" "unprognostic (2.86e-3)" "unprognostic (2.40e-1)" "unprognostic (1.37e-1)" "unprognostic (6.38e-2)" "unprognostic (2.85e-2)" "potential prognostic unfavorable (3.37e-5)" "unprognostic (8.99e-2)" "unprognostic (9.23e-2)" "potential prognostic unfavorable (1.20e-5)" "unprognostic (1.34e-1)" "unprognostic (2.15e-1)" "unprognostic (6.34e-2)" "unprognostic (2.06e-2)" "unprognostic (8.49e-2)" "unprognostic (5.53e-1)" "unprognostic (4.00e-1)" "unprognostic (7.74e-2)" "unprognostic (2.19e-1)" "potential prognostic unfavorable (3.33e-4)" "unprognostic (2.94e-1)" "unprognostic (1.36e-1)" "unprognostic (8.94e-2)" "unprognostic (2.59e-2)" "unprognostic (2.13e-3)" "unprognostic (1.76e-1)" "unprognostic (1.98e-1)" "potential prognostic favorable (4.37e-4)" "unprognostic (2.48e-2)" LIPI "CT17, LPDL, mPA-PLA1beta, PLA1C, PRED5" ENSG00000188992 "Lipase I" Q6XZB0 21 14108813-14210955 "Predicted secreted proteins" "Lipid degradation, Lipid metabolism" "Heparin-binding, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 169 "epididymis: 395.8" "Cell type enriched" "Detected in some" 9 "Epididymal principal cells: 497.2" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 54 "Bone cancer: 22.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA049665 Supported "Plasma membrane" "Secreted in male reproductive system" Enzyme NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" "Plasma membrane" "HPA049665: " LIPJ "bA425M17.2, LIPL1" ENSG00000204022 "Lipase family member J" Q5W064 10 88586753-88606976 "Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 7 "testis: 6.5" "Group enriched" "Detected in some" 4 "Early spermatids: 40.5;Ependymal cells: 28.1;Late primary spermatocytes: 85.4" "Cell type enriched" "Detected in some" 8 "ependymal cell: 24.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Stomach - Chief cells, Testis - Early spermatids, Testis - Late spermatids" HPA048594 Uncertain Approved "Plasma membrane" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 2: Neurons - Nucleosome" "Cluster 61: BICR 18 - Protein kinases" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" "Plasma membrane" "HPA048594: " LIPK "bA186O14.2, LIPL2" ENSG00000204021 "Lipase family member K" Q5VXJ0 10 88706249-88752776 "Predicted secreted proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "skin 1: 27.4" "Group enriched" "Detected in some" 4 "Esophageal apical cells: 16.0;Suprabasal keratinocytes: 20.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Head and Neck Squamous Cell Carcinoma (TCGA): 2.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Stomach - Chief cells" "Not detected" "Not detected" "Secreted in other tissues" Enzyme NA NA "Cluster 37: Skin - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" "unprognostic (1.05e-1)" LIPM "bA304I5.1, LIPL3" ENSG00000173239 "Lipase family member M" Q5VYY2 10 88802730-88820546 "Predicted intracellular proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 14 "skin 1: 26.5" "Cell type enhanced" "Detected in some" "Gastric chief cells: 1.1;Mesothelial cells: 1.4;Oocytes: 4.6;Suprabasal keratinocytes: 3.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA071276 Approved "Endoplasmic reticulum" "Secreted in other tissues" Enzyme NA NA "Cluster 37: Skin - Keratinization" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" "Endoplasmic reticulum" "HPA071276: " LIPN "bA186O14.3, LIPL4" ENSG00000204020 "Lipase family member N" Q5VXI9 10 88759982-88779626 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" Hydrolase Ichthyosis "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "skin 1: 25.2" "Group enriched" "Detected in some" 7 "monocytes: 79.7;Neutrophils: 253.2" "Cell type enriched" "Detected in some" 7 "leukocyte: 12.0" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "classical monocyte: 2.9;eosinophil: 10.3;intermediate monocyte: 7.5;neutrophil: 5.4;non-classical monocyte: 8.5" "Group enriched" "Detected in many" 8 "granulocytes: 10.3;monocytes: 8.5" "Not detected" "Not detected" "Adipose visceral - Neutrophils, Colon - Neutrophils, Kidney - Macrophages, Lung - Neutrophils_2, Skin - Keratinocyte (granular), Spleen - Neutrophils_2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted in other tissues" Enzyme NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 37: Skin - Keratinization" "Cluster 55: Lymphoma - Immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" LIPT1 "MGC12290, MGC13378" ENSG00000144182 "Lipoyltransferase 1" Q9Y234 2 99154955-99163157 "Disease related genes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Early spermatids: 1.8;Endometrial secretory cells: 1.3;Gastric progenitor cells: 1.3;Hematopoietic stem cells: 1.5;Late primary spermatocytes: 2.8;pDCs: 1.3;Smooth muscle cells: 2.9" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" HPA034802 Approved NA NA "Cluster 1: T-cells - Unknown function" "Cluster 22: Epididymis - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 8 "HPA034802: " "unprognostic (2.01e-1)" "unprognostic (1.34e-1)" "unprognostic (8.36e-2)" "unprognostic (5.50e-2)" "unprognostic (1.12e-3)" "unprognostic (1.12e-1)" "unprognostic (1.75e-2)" "unprognostic (3.20e-1)" "unprognostic (7.75e-3)" "unprognostic (7.54e-2)" "unprognostic (1.69e-3)" "unprognostic (2.91e-2)" "unprognostic (3.08e-1)" "potential prognostic unfavorable (1.37e-5)" "unprognostic (9.46e-2)" "unprognostic (6.19e-2)" "unprognostic (1.79e-1)" "potential prognostic favorable (6.49e-4)" "unprognostic (9.06e-2)" "unprognostic (1.43e-1)" "unprognostic (6.47e-2)" "unprognostic (4.73e-2)" "unprognostic (1.40e-2)" "unprognostic (1.37e-1)" "potential prognostic favorable (2.85e-4)" "unprognostic (4.37e-2)" "unprognostic (1.59e-2)" "unprognostic (7.28e-2)" "unprognostic (1.05e-1)" "unprognostic (8.66e-2)" "unprognostic (2.30e-1)" LIPT2 ENSG00000175536 "Lipoyl(octanoyl) transferase 2" A6NK58 11 74490519-74493724 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Acyltransferase, Ligase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 10.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 50.7;Early primary spermatocytes: 28.8;Early spermatids: 61.0;Extravillous trophoblasts: 21.7;Late primary spermatocytes: 79.6;Late spermatids: 35.4;Oocytes: 36.8" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040249 Approved NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" "HPA040249: " "unprognostic (1.86e-2)" "unprognostic (3.08e-1)" "unprognostic (2.26e-1)" "unprognostic (6.60e-2)" "potential prognostic favorable (1.69e-4)" "potential prognostic unfavorable (3.81e-4)" "unprognostic (6.96e-2)" "unprognostic (1.04e-1)" "unprognostic (1.46e-1)" "unprognostic (6.15e-3)" "unprognostic (1.46e-3)" "unprognostic (1.16e-1)" "unprognostic (1.26e-2)" "unprognostic (1.76e-2)" "unprognostic (1.26e-2)" "unprognostic (9.22e-2)" "unprognostic (2.21e-1)" "unprognostic (2.22e-2)" "unprognostic (6.83e-3)" "unprognostic (3.45e-3)" "unprognostic (2.44e-1)" "unprognostic (1.07e-1)" "potential prognostic favorable (3.10e-4)" "unprognostic (1.33e-1)" "unprognostic (5.60e-2)" "unprognostic (1.12e-1)" "unprognostic (8.49e-2)" "unprognostic (3.75e-1)" "unprognostic (1.89e-1)" "unprognostic (2.66e-2)" "unprognostic (7.26e-2)" LITAF "FLJ38636, PIG7, SIMPLE, TP53I7" ENSG00000189067 "Lipopolysaccharide induced TNF factor" Q99732 16 11547722-11636381 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" DNA-binding "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 8 "Neutrophils: 7072.3" "Cell type enhanced" "Detected in many" "leukocyte: 212.6;oligodendrocyte: 117.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "neutrophil: 2587.2" "Lineage enriched" "Detected in all" 6 "granulocytes: 2587.2" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Endothelial cells" "Low region specificity" "Detected in all" HPA006960 Approved Supported "Nucleoplasm,Nuclear speckles,Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 30: White matter - Myelination" "Cluster 15: Kidney cancer - Membrane components" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 62 Nucleoplasm "Nuclear speckles, Golgi apparatus, Vesicles, Plasma membrane" "HPA006960: " "unprognostic (3.18e-2)" "unprognostic (1.23e-1)" "unprognostic (1.31e-3)" "unprognostic (3.25e-1)" "unprognostic (4.19e-2)" "unprognostic (1.46e-1)" "unprognostic (1.19e-3)" "unprognostic (3.25e-3)" "unprognostic (3.52e-2)" "unprognostic (1.77e-1)" "unprognostic (1.90e-3)" "unprognostic (1.28e-1)" "unprognostic (2.49e-2)" "unprognostic (3.61e-2)" "unprognostic (1.86e-1)" "unprognostic (5.74e-2)" "unprognostic (1.23e-1)" "unprognostic (6.87e-2)" "unprognostic (4.16e-1)" "unprognostic (2.91e-3)" "unprognostic (4.80e-3)" "unprognostic (1.03e-1)" "unprognostic (1.71e-1)" "unprognostic (3.03e-1)" "unprognostic (3.29e-3)" "unprognostic (1.70e-1)" "unprognostic (2.22e-1)" "unprognostic (8.78e-2)" "potential prognostic unfavorable (4.73e-4)" "unprognostic (1.37e-2)" "unprognostic (7.99e-2)" LITAFD ENSG00000283516 "LITAF domain containing" A0A1B0GVX0 16 8882351-8885351 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 20 "testis: 6.8" "Group enriched" "Detected in some" 27 "Early spermatids: 206.8;Late spermatids: 328.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Corticotropes, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 15: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" "unprognostic (2.42e-1)" "unprognostic (7.71e-2)" "unprognostic (1.39e-1)" LIX1 "C5orf11, Lft" ENSG00000145721 "Limb and CNS expressed 1" Q8N485 5 97091867-97142753 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 25.9;retina: 39.5" "Cell type enhanced" "Detected in some" "Astrocytes: 50.7;B-cells: 20.1;Bergmann glia: 16.7;Epididymal efferent duct absorptive cells: 53.1;Loop of henle epithelial cells: 37.2;Müller glia: 210.0;Pituitary stem cells: 59.7;Retinal amacrine cells: 15.7" "Group enriched" "Detected in many" 4 "astrocyte: 63.8;Bergmann glia: 19.0;ependymal cell: 19.9" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 25.0;Ovary Serous Cystadenocarcinoma (TCGA): 12.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 2.2" "Lineage enriched" "Detected in single" 6 "B-cells: 2.2" "Cancer enhanced" "Detected in many" "ovarian cancer: 11.4;testis cancer: 28.9" "Colon - Colon enteroendocrine cells, Kidney - Fibroblasts, Skin - Inner root sheath cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058426 Uncertain Approved "Vesicles,Cytokinetic bridge,Cytosol" Yes NA "Cluster 34: B-cells - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 39: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 11: Muller glia cells - Retinal homeostasis" 4 Cytosol "Vesicles, Cytokinetic bridge" "HPA058426: " "unprognostic (4.63e-1)" "unprognostic (8.44e-2)" "unprognostic (3.63e-2)" "unprognostic (3.67e-2)" "unprognostic (4.31e-1)" "unprognostic (1.71e-2)" "unprognostic (1.73e-3)" "unprognostic (2.49e-1)" "unprognostic (7.61e-2)" "unprognostic (2.99e-1)" LIX1L MGC46719 ENSG00000271601 "Limb and CNS expressed 1 like" Q8IVB5 1 145933423-145958017 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Thymic myoid cells: 92.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063598 Approved Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 24: Non-specific - Transcription" "Cluster 39: Astrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 62: Smooth muscle cells - Muscle contraction" 1 Cytosol "HPA063598: " "unprognostic (5.61e-2)" "unprognostic (5.05e-2)" "unprognostic (8.82e-2)" "unprognostic (2.81e-2)" "unprognostic (7.76e-2)" "unprognostic (1.12e-2)" "unprognostic (6.24e-2)" "unprognostic (1.00e-1)" "unprognostic (2.21e-1)" "potential prognostic favorable (8.24e-5)" "unprognostic (1.28e-3)" "unprognostic (3.89e-2)" "potential prognostic unfavorable (2.14e-4)" "unprognostic (2.23e-1)" "unprognostic (8.77e-3)" "unprognostic (1.29e-2)" "unprognostic (8.90e-2)" "unprognostic (2.48e-1)" "unprognostic (1.58e-2)" "unprognostic (3.47e-3)" "unprognostic (1.41e-1)" "unprognostic (1.69e-2)" "unprognostic (2.02e-1)" "unprognostic (5.57e-2)" "unprognostic (5.87e-3)" "unprognostic (1.12e-1)" "unprognostic (3.50e-2)" "unprognostic (4.68e-1)" LKAAEAR1 C20orf201 ENSG00000171695 "LKAAEAR motif containing 1" Q8TD35 20 64083376-64084398 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 29.1" "Group enriched" "Detected in some" 7 "Early spermatids: 495.8;Late primary spermatocytes: 312.5;Late spermatids: 890.3" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 2.2;Ovary Serous Cystadenocarcinoma (TCGA): 2.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "intermediate monocyte: 8.2;non-classical monocyte: 13.0" "Lineage enriched" "Detected in many" 13 "monocytes: 13.0" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA056463 Approved Nucleoplasm NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 67: Testis - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" Nucleoplasm "HPA056463: " "unprognostic (4.12e-1)" "unprognostic (6.75e-2)" "unprognostic (6.81e-3)" "unprognostic (1.28e-2)" LLCFC1 "C7orf34, CTM-1" ENSG00000165131 "LLLL and CFNLAS motif containing 1" Q96L11 7 142939343-142940868 "Predicted intracellular proteins, Predicted secreted proteins" Fertilization "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 39 "testis: 61.0" "Group enriched" "Detected in some" 31 "Early spermatids: 10.8;Late primary spermatocytes: 4.0;Late spermatids: 6.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Leukemia: 1.0" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Spleen - Neutrophils_2, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" Other NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 30: White matter - Myelination" "Cluster 47: Leukemia - Hemostasis" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" LLGL1 "DLG4, HUGL, HUGL-1, Lgl1, LLGL, Mgl1" ENSG00000131899 "LLGL scribble cell polarity complex component 1" Q15334 17 18225635-18244875 "Predicted intracellular proteins" Exocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "brain: 64.9" "Cell type enhanced" "Detected in some" "Astrocytes: 5.9;Bergmann glia: 4.5;Ependymal cells: 7.1;Oligodendrocyte progenitor cells: 3.7;Oligodendrocytes: 22.4;Retinal ganglion cells: 3.9" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 16.0;oligodendrocyte: 25.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022924 Enhanced NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 80: Oligodendrocytes - Myelination" 35 "HPA022924: " "unprognostic (2.09e-1)" "unprognostic (2.49e-2)" "unprognostic (1.15e-3)" "unprognostic (3.80e-2)" "unprognostic (3.13e-1)" "unprognostic (4.08e-1)" "unprognostic (1.34e-1)" "unprognostic (1.88e-1)" "unprognostic (5.07e-3)" "unprognostic (2.46e-2)" "unprognostic (1.91e-3)" "unprognostic (2.49e-1)" "unprognostic (1.24e-1)" "potential prognostic unfavorable (3.08e-4)" "unprognostic (1.10e-1)" "unprognostic (2.81e-1)" "unprognostic (2.97e-2)" "unprognostic (1.16e-1)" "unprognostic (2.37e-1)" "unprognostic (1.31e-1)" "unprognostic (3.96e-1)" "unprognostic (1.94e-2)" "unprognostic (8.76e-3)" "unprognostic (3.47e-2)" "unprognostic (7.79e-3)" "unprognostic (6.23e-3)" "unprognostic (2.98e-1)" "unprognostic (7.33e-2)" "unprognostic (2.31e-1)" "unprognostic (4.18e-2)" "unprognostic (1.93e-1)" LLGL2 "HGL, Hugl-2" ENSG00000073350 "LLGL scribble cell polarity complex component 2" Q6P1M3 17 75525080-75575209 "Predicted intracellular proteins" "Cell cycle, Cell division, Exocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 597.0;Colonocytes: 580.7;Distal convoluted tubule cells: 340.7" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 46.1;leukocyte: 72.5;oligodendrocyte: 48.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 3.1" "Group enriched" "Detected in many" 6 "dendritic cells: 1.1;NK-cells: 2.1;T-cells: 3.1" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Colon - Colon enterocytes, Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" HPA022913 Uncertain Supported Vesicles,Cytosol NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 60: Stomach - Digestion" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 65: Non-specific - Cell growth & division" 18 Cytosol Vesicles "HPA022913: " "unprognostic (4.79e-2)" "unprognostic (8.50e-2)" "unprognostic (3.49e-1)" "unprognostic (3.59e-2)" "unprognostic (1.45e-2)" "unprognostic (1.72e-1)" "unprognostic (1.61e-1)" "unprognostic (1.46e-2)" "unprognostic (4.64e-2)" "validated prognostic favorable (7.06e-11)" "validated prognostic favorable (4.01e-5)" "potential prognostic favorable (5.56e-4)" "unprognostic (1.51e-1)" "unprognostic (2.93e-2)" "unprognostic (7.92e-2)" "unprognostic (6.56e-2)" "unprognostic (8.93e-3)" "unprognostic (3.74e-2)" "unprognostic (8.55e-2)" "unprognostic (1.62e-2)" "unprognostic (4.78e-2)" "unprognostic (1.19e-1)" "potential prognostic unfavorable (9.62e-4)" "unprognostic (2.64e-3)" "unprognostic (6.03e-2)" "unprognostic (1.35e-1)" "unprognostic (5.20e-2)" "unprognostic (1.51e-1)" "unprognostic (1.05e-1)" "unprognostic (2.08e-1)" LLPH "C12orf31, hLLP, MGC14817" ENSG00000139233 "LLP homolog, long-term synaptic facilitation factor" Q9BRT6 12 66116555-66130750 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 181.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048920, HPA058786" Enhanced "Nucleoli,Mitotic chromosome" Yes No "Cluster 25: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 21 Nucleoli "Mitotic chromosome" "HPA048920: , HPA058786: " "potential prognostic unfavorable (2.23e-4)" "unprognostic (1.09e-2)" "unprognostic (2.99e-1)" "unprognostic (1.21e-1)" "unprognostic (3.35e-1)" "unprognostic (1.83e-1)" "unprognostic (1.65e-1)" "unprognostic (3.49e-1)" "unprognostic (7.17e-3)" "unprognostic (1.52e-2)" "unprognostic (2.90e-3)" "unprognostic (1.65e-1)" "unprognostic (2.00e-3)" "validated prognostic unfavorable (6.90e-10)" "validated prognostic unfavorable (1.50e-4)" "potential prognostic unfavorable (4.24e-4)" "unprognostic (8.16e-3)" "unprognostic (2.25e-2)" "unprognostic (2.25e-1)" "unprognostic (8.74e-3)" "unprognostic (1.50e-1)" "unprognostic (5.86e-3)" "unprognostic (7.03e-2)" "unprognostic (6.11e-2)" "unprognostic (2.54e-1)" "unprognostic (7.19e-3)" "unprognostic (2.85e-2)" "unprognostic (1.30e-2)" "unprognostic (4.50e-2)" "unprognostic (1.49e-1)" "unprognostic (1.14e-2)" LMAN1 "ERGIC-53, ERGIC53, F5F8D, FMFD1, gp58, MCFD1, MR60" ENSG00000074695 "Lectin, mannose binding 1" P49257 18 59327823-59359265 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 476.0;Plasma cells: 575.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002320, CAB037163" Supported Supported "Endoplasmic reticulum,Vesicles" NA NA 8600000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 55: Non-specific - Transcription" "Cluster 13: Non-specific - Mixed function" "Cluster 44: Plasma cells - Antibody production & secretion" 49 Vesicles "Endoplasmic reticulum" "CAB037163: , HPA002320: " "unprognostic (1.04e-1)" "unprognostic (3.88e-2)" "unprognostic (7.93e-2)" "unprognostic (2.71e-2)" "unprognostic (2.87e-2)" "unprognostic (2.51e-1)" "unprognostic (1.76e-2)" "unprognostic (7.01e-3)" "unprognostic (2.72e-1)" "unprognostic (8.02e-2)" "potential prognostic favorable (1.73e-4)" "unprognostic (1.09e-1)" "unprognostic (7.98e-3)" "unprognostic (1.28e-1)" "potential prognostic unfavorable (1.00e-4)" "potential prognostic unfavorable (7.09e-4)" "unprognostic (4.10e-2)" "unprognostic (1.02e-1)" "unprognostic (4.24e-1)" "unprognostic (1.26e-1)" "unprognostic (5.78e-2)" "unprognostic (1.83e-2)" "unprognostic (1.12e-3)" "unprognostic (2.08e-1)" "unprognostic (5.68e-2)" "unprognostic (1.54e-1)" "unprognostic (7.04e-2)" "unprognostic (1.01e-1)" "unprognostic (1.22e-1)" "unprognostic (3.12e-2)" "unprognostic (3.78e-1)" LMAN1L "ERGIC-53L, ERGL" ENSG00000140506 "Lectin, mannose binding 1 like" Q9HAT1 15 74812716-74825757 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 24.1;heart muscle: 31.5;lymphoid tissue: 24.2;prostate: 57.2;salivary gland: 19.5" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 1.4;Cardiomyocytes: 3.4;Cone photoreceptor cells: 2.1;Prostatic glandular cells: 3.1;Retinal bipolar cells: 1.1" "Cell type enhanced" "Detected in some" "astrocyte: 2.1;CGE interneuron: 1.5;upper rhombic lip: 2.5" "Cancer enriched" "Detected in single" 36 "Prostate Adenocarcinoma (TCGA): 34.0" "Region enhanced" "Detected in many" "cerebellum: 29.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "prostate cancer: 5.2" "Heart muscle - Cardiomyocytes, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Thyrotropes, Prostate - Prostate glandular cells" "Not detected" "Not detected" "Region enhanced" "Detected in single" "spinal cord: 1.9" NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 25: Non-specific - Transcription" "Cluster 60: Prostate cancer - Unknown function" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" "unprognostic (1.43e-3)" LMAN2 "C5orf8, GP36B, VIP36" ENSG00000169223 "Lectin, mannose binding 2" Q12907 5 177315805-177351840 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epididymal principal cells: 569.9;Esophageal apical cells: 568.4;Esophageal suprabasal cells: 594.1;Extravillous trophoblasts: 615.3;Syncytiotrophoblasts: 697.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Breast - Breast glandular cells, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003927, CAB033812" Approved Supported "Golgi apparatus" NA NA 29000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 70: Non-specific - Protein processing" "Cluster 36: Choroid plexus - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 8: Non-specific - Secretory pathway" 25 "Golgi apparatus" "CAB033812: , HPA003927: " "unprognostic (5.00e-2)" "unprognostic (9.04e-3)" "unprognostic (1.27e-1)" "unprognostic (4.63e-2)" "unprognostic (4.57e-3)" "unprognostic (6.74e-2)" "unprognostic (2.90e-2)" "unprognostic (7.37e-3)" "potential prognostic unfavorable (1.95e-4)" "unprognostic (5.11e-3)" "unprognostic (1.79e-2)" "unprognostic (3.51e-2)" "potential prognostic unfavorable (2.10e-4)" "unprognostic (1.76e-3)" "unprognostic (1.48e-1)" "unprognostic (4.04e-2)" "unprognostic (1.52e-1)" "unprognostic (1.97e-2)" "unprognostic (1.76e-1)" "unprognostic (1.02e-3)" "unprognostic (5.91e-2)" "unprognostic (1.20e-1)" "unprognostic (3.77e-1)" "unprognostic (1.76e-1)" "unprognostic (7.74e-2)" "unprognostic (1.10e-1)" "unprognostic (1.29e-1)" "unprognostic (1.11e-1)" "unprognostic (1.16e-1)" "unprognostic (7.75e-3)" "unprognostic (1.94e-1)" LMAN2L "DKFZp564L2423, VIPL" ENSG00000114988 "Lectin, mannose binding 2 like" Q9H0V9 2 96705929-96740064 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 78.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026600 Approved NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 27: Breast cancer - Unknown function" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 11 "HPA026600: " "unprognostic (1.07e-1)" "unprognostic (6.41e-2)" "unprognostic (2.91e-1)" "unprognostic (3.88e-1)" "unprognostic (4.15e-2)" "unprognostic (2.72e-1)" "unprognostic (9.87e-2)" "unprognostic (2.41e-2)" "unprognostic (4.95e-3)" "unprognostic (3.62e-1)" "unprognostic (8.36e-3)" "unprognostic (9.71e-2)" "potential prognostic unfavorable (3.24e-4)" "validated prognostic unfavorable (5.69e-4)" "validated prognostic unfavorable (9.97e-4)" "unprognostic (1.88e-2)" "unprognostic (3.42e-1)" "unprognostic (4.42e-2)" "unprognostic (1.13e-1)" "unprognostic (3.08e-1)" "unprognostic (3.30e-2)" "unprognostic (1.10e-2)" "unprognostic (1.72e-2)" "unprognostic (6.03e-2)" "unprognostic (5.35e-2)" "unprognostic (7.09e-2)" "potential prognostic favorable (8.15e-4)" "unprognostic (1.78e-2)" "unprognostic (5.17e-2)" "unprognostic (9.06e-2)" "unprognostic (1.69e-2)" LMBR1 "ACHP, C7orf2, FLJ11665, ZRS" ENSG00000105983 "Limb development membrane protein 1" Q8WVP7 7 156668946-156893216 "Disease related genes, Human disease related genes, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophil progenitors: 627.8;Sertoli cells: 690.4" "Cell type enhanced" "Detected in all" "endothelial cell: 640.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016592 Approved Approved Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 39: Non-specific - Transcription" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 3 Cytosol "HPA016592: " "unprognostic (5.84e-2)" "unprognostic (1.31e-2)" "unprognostic (2.60e-2)" "unprognostic (1.44e-2)" "unprognostic (9.43e-2)" "unprognostic (1.88e-2)" "unprognostic (6.54e-2)" "unprognostic (2.58e-1)" "unprognostic (1.88e-1)" "potential prognostic unfavorable (4.23e-4)" "potential prognostic favorable (5.45e-7)" "unprognostic (8.91e-2)" "unprognostic (4.13e-2)" "unprognostic (9.26e-3)" "unprognostic (2.17e-2)" "unprognostic (6.32e-3)" "unprognostic (3.46e-3)" "unprognostic (9.88e-2)" "unprognostic (2.04e-1)" "unprognostic (8.58e-2)" "unprognostic (1.34e-2)" "unprognostic (3.54e-1)" "unprognostic (9.53e-2)" "unprognostic (1.25e-1)" "unprognostic (1.07e-1)" "unprognostic (8.19e-2)" "unprognostic (3.05e-2)" "unprognostic (1.74e-1)" "unprognostic (1.83e-1)" "unprognostic (3.65e-2)" "unprognostic (9.96e-2)" LMBR1L "FLJ10494, KIAA1174" ENSG00000139636 "Limb development membrane protein 1 like" Q6UX01 12 49097136-49110900 "Essential proteins, Predicted membrane proteins" "Endocytosis, Wnt signaling pathway" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 140.4;Esophageal apical cells: 128.0;Late spermatids: 271.3;Sertoli cells: 109.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 67: Testis - Mixed function" "Cluster 25: Non-specific - Transcription" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 9 "unprognostic (1.39e-1)" "unprognostic (1.42e-3)" "unprognostic (9.80e-2)" "unprognostic (9.92e-3)" "unprognostic (1.85e-1)" "unprognostic (1.62e-1)" "unprognostic (3.36e-2)" "unprognostic (4.67e-3)" "unprognostic (6.40e-2)" "unprognostic (2.90e-1)" "unprognostic (1.06e-1)" "unprognostic (4.13e-2)" "unprognostic (8.09e-2)" "potential prognostic unfavorable (7.32e-4)" "unprognostic (7.22e-2)" "unprognostic (2.59e-2)" "unprognostic (1.52e-3)" "unprognostic (1.53e-1)" "unprognostic (4.18e-2)" "unprognostic (3.12e-1)" "unprognostic (3.92e-1)" "unprognostic (7.92e-3)" "potential prognostic unfavorable (9.34e-5)" "unprognostic (9.11e-2)" "unprognostic (3.40e-1)" "unprognostic (2.09e-1)" "unprognostic (2.63e-3)" "unprognostic (5.98e-2)" "unprognostic (1.79e-1)" "unprognostic (1.02e-1)" "unprognostic (1.57e-1)" LMBRD1 "bA810I22.1, C6orf209, cblF, FLJ11240" ENSG00000168216 "LMBR1 domain containing 1" Q9NUN5 6 69672757-69867236 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Endocytosis, Gastrulation, Host-virus interaction, Transport" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "naive B-cell: 21.2" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016491, HPA019547" Uncertain Supported Vesicles NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 25: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 4 Vesicles "HPA016491: , HPA019547: " "unprognostic (4.34e-2)" "unprognostic (9.87e-3)" "unprognostic (4.81e-2)" "unprognostic (1.03e-1)" "unprognostic (2.05e-1)" "unprognostic (1.03e-2)" "unprognostic (2.98e-1)" "potential prognostic unfavorable (3.09e-4)" "unprognostic (2.68e-1)" "unprognostic (1.19e-2)" "potential prognostic favorable (3.48e-9)" "unprognostic (4.08e-3)" "unprognostic (9.34e-2)" "unprognostic (2.17e-1)" "unprognostic (4.67e-2)" "unprognostic (2.07e-1)" "unprognostic (4.06e-2)" "unprognostic (1.53e-1)" "unprognostic (9.41e-3)" "unprognostic (1.25e-1)" "unprognostic (1.22e-3)" "unprognostic (4.38e-2)" "unprognostic (7.04e-2)" "unprognostic (1.29e-1)" "unprognostic (7.06e-2)" "unprognostic (1.83e-1)" "unprognostic (9.30e-2)" "unprognostic (3.07e-2)" "unprognostic (4.21e-2)" "unprognostic (1.58e-1)" "unprognostic (3.27e-2)" LMBRD2 DKFZp434H2226 ENSG00000164187 "LMBR1 domain containing 2" Q68DH5 5 36098407-36151887 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "basophil: 10.6" "Lineage enriched" "Detected in many" 6 "granulocytes: 10.6" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Pituitary gland - Lactotropes, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012165 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 32: Basophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 29: Non-specific - Unknown function" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 2 "Nucleoplasm, Cytosol" "HPA012165: " "unprognostic (2.32e-1)" "unprognostic (1.46e-3)" "unprognostic (1.52e-1)" "unprognostic (1.36e-1)" "unprognostic (5.94e-2)" "unprognostic (2.63e-1)" "unprognostic (2.59e-1)" "unprognostic (5.85e-2)" "unprognostic (1.88e-2)" "potential prognostic unfavorable (3.37e-5)" "potential prognostic favorable (3.58e-6)" "unprognostic (1.20e-2)" "unprognostic (1.28e-1)" "unprognostic (4.37e-2)" "unprognostic (4.79e-2)" "unprognostic (1.01e-1)" "unprognostic (2.38e-1)" "unprognostic (1.54e-1)" "unprognostic (1.95e-1)" "unprognostic (3.36e-1)" "unprognostic (1.21e-2)" "unprognostic (1.80e-1)" "unprognostic (1.86e-3)" "unprognostic (1.15e-1)" "unprognostic (1.08e-1)" "unprognostic (7.22e-2)" "unprognostic (2.46e-2)" "unprognostic (7.05e-2)" "unprognostic (2.04e-1)" "unprognostic (5.92e-2)" "unprognostic (7.08e-2)" LMCD1 ENSG00000071282 "LIM and cysteine rich domains 1" Q9NZU5 3 8501807-8574668 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 381.9;skeletal muscle: 537.1" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 479.6;Hepatic stellate cells: 458.3;Myonuclei: 488.6;Pericytes: 218.1;Smooth muscle cells: 1089.9;Thymic myoid cells: 522.1;Vascular endothelial cells: 278.7" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 161.9;endothelial cell: 254.0;vascular associated smooth muscle cell: 109.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "T-reg: 20.6" "Lineage enriched" "Detected in many" 6 "T-cells: 20.6" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Spleen - Fibroblasts_2, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024059 Enhanced Approved "Nucleoplasm,Plasma membrane,Cell Junctions,Cytosol" No No 5700 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 27: Breast cancer - Unknown function" "Cluster 103: Non-specific - Basic cellular processes" 2 "Nucleoplasm, Plasma membrane" "Cell Junctions, Cytosol" "HPA024059: " "unprognostic (2.76e-2)" "unprognostic (3.21e-1)" "unprognostic (4.21e-2)" "unprognostic (9.28e-2)" "unprognostic (3.11e-3)" "unprognostic (2.56e-2)" "unprognostic (3.20e-2)" "unprognostic (2.83e-2)" "unprognostic (5.49e-2)" "unprognostic (2.52e-2)" "unprognostic (2.12e-3)" "unprognostic (1.64e-2)" "potential prognostic unfavorable (7.86e-4)" "unprognostic (5.99e-2)" "unprognostic (3.27e-1)" "unprognostic (4.93e-1)" "unprognostic (2.06e-1)" "unprognostic (3.44e-2)" "unprognostic (2.95e-1)" "unprognostic (1.44e-2)" "unprognostic (2.09e-1)" "unprognostic (2.32e-1)" "unprognostic (2.04e-2)" "unprognostic (1.58e-2)" "unprognostic (2.67e-2)" "unprognostic (9.75e-3)" "unprognostic (1.97e-1)" "unprognostic (2.10e-2)" "unprognostic (1.27e-1)" "potential prognostic unfavorable (8.67e-4)" "unprognostic (2.45e-1)" LMF1 "C16orf26, FLJ12681, FLJ22302, JFP11, TMEM112, TMEM112A" ENSG00000103227 "Lipase maturation factor 1" Q96S06 16 853634-981318 "Disease related genes, Human disease related genes, Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 70: Non-specific - Protein processing" "Cluster 11: White matter - Signal transduction" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 7: Non-specific - Transcription" 19 "unprognostic (1.00e-1)" "unprognostic (7.50e-2)" "unprognostic (2.79e-2)" "unprognostic (1.91e-2)" "unprognostic (9.47e-2)" "unprognostic (2.26e-1)" "unprognostic (4.68e-2)" "unprognostic (1.08e-1)" "unprognostic (6.52e-2)" "unprognostic (2.37e-1)" "unprognostic (4.74e-2)" "unprognostic (9.58e-3)" "potential prognostic favorable (8.26e-4)" "unprognostic (7.53e-3)" "unprognostic (2.00e-2)" "unprognostic (3.64e-3)" "unprognostic (1.38e-1)" "unprognostic (1.31e-1)" "unprognostic (1.56e-2)" "unprognostic (1.27e-1)" "unprognostic (2.03e-1)" "unprognostic (1.84e-1)" "unprognostic (6.16e-2)" "unprognostic (2.76e-2)" "unprognostic (1.58e-2)" "unprognostic (1.38e-1)" "unprognostic (6.44e-2)" "unprognostic (5.53e-2)" "unprognostic (3.68e-1)" "unprognostic (1.60e-2)" "unprognostic (1.30e-1)" LMF2 "TMEM112B, TMEM153" ENSG00000100258 "Lipase maturation factor 2" Q9BU23 22 50502949-50507702 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 170.5" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 138.4;Oocytes: 110.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062626 Approved Approved Centrosome NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 70: Non-specific - Protein processing" "Cluster 44: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 6 Centrosome "HPA062626: " "unprognostic (5.68e-2)" "unprognostic (2.99e-1)" "unprognostic (7.22e-2)" "unprognostic (1.99e-1)" "unprognostic (9.30e-2)" "unprognostic (9.57e-2)" "unprognostic (2.11e-1)" "unprognostic (4.56e-2)" "unprognostic (1.39e-1)" "unprognostic (2.49e-1)" "unprognostic (5.83e-2)" "unprognostic (2.59e-1)" "unprognostic (5.25e-3)" "unprognostic (3.35e-3)" "unprognostic (1.07e-2)" "unprognostic (1.68e-1)" "unprognostic (1.96e-1)" "unprognostic (4.17e-3)" "unprognostic (1.45e-1)" "unprognostic (1.22e-1)" "potential prognostic favorable (8.46e-4)" "unprognostic (3.02e-1)" "unprognostic (6.47e-2)" "unprognostic (8.64e-2)" "unprognostic (5.23e-2)" "unprognostic (6.66e-3)" "unprognostic (4.19e-2)" "unprognostic (5.38e-2)" "unprognostic (6.88e-2)" "unprognostic (6.77e-3)" "unprognostic (2.98e-1)" LMLN "Gp63, LMNL1, Msp" ENSG00000185621 "Leishmanolysin like peptidase" Q96KR4 3 197960200-198043720 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Mitosis" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ependymal cells: 130.7;Respiratory ciliated cells: 96.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016481, HPA028844" Uncertain Supported "Focal adhesion sites,Cytosol" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 22: Epididymis - Mixed function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" Cytosol "Focal adhesion sites" "HPA016481: , HPA028844: " "unprognostic (1.76e-1)" "unprognostic (1.21e-2)" "unprognostic (6.28e-2)" "unprognostic (1.12e-1)" "unprognostic (3.74e-1)" "unprognostic (4.01e-2)" "unprognostic (4.86e-2)" "unprognostic (8.58e-3)" "unprognostic (1.55e-1)" "unprognostic (2.48e-3)" "unprognostic (3.13e-2)" "unprognostic (2.08e-1)" "unprognostic (1.25e-1)" "unprognostic (4.30e-1)" "unprognostic (2.78e-2)" "unprognostic (4.65e-2)" "unprognostic (7.58e-2)" "unprognostic (1.22e-2)" "unprognostic (1.37e-1)" "unprognostic (9.99e-2)" "unprognostic (2.81e-2)" "unprognostic (3.80e-2)" "unprognostic (8.62e-2)" "unprognostic (1.05e-1)" "unprognostic (3.35e-3)" "unprognostic (3.73e-1)" "unprognostic (2.37e-1)" "unprognostic (2.25e-1)" "unprognostic (3.27e-2)" "unprognostic (2.57e-1)" LMNA "CMD1A, HGPS, LGMD1B, LMN1, LMNL1, MADA, PRO1" ENSG00000160789 "Lamin A/C" P02545 1 156082573-156140081 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Cardiomyopathy, Charcot-Marie-Tooth disease, Congenital muscular dystrophy, Disease variant, Emery-Dreifuss muscular dystrophy, Limb-girdle muscular dystrophy, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Mast cells: 2669.0;Schwann cells: 1415.6" "Cell type enhanced" "Detected in all" "pericyte: 159.9;vascular associated smooth muscle cell: 192.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 98.1;T-reg: 98.9" "Group enriched" "Detected in all" 8 "dendritic cells: 98.1;granulocytes: 30.6;T-cells: 98.9" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004022, HPA006523, HPA006660" Supported Supported "Nuclear speckles" NA NA 8000000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 58: Mast cells - Allergic inflammatory responses" 345 "Nuclear speckles" "CAB004022: , HPA006523: , HPA006660: " "unprognostic (2.35e-1)" "unprognostic (1.53e-1)" "unprognostic (1.75e-1)" "unprognostic (2.88e-2)" "unprognostic (3.77e-1)" "unprognostic (1.21e-2)" "unprognostic (4.69e-2)" "unprognostic (2.67e-2)" "unprognostic (1.80e-1)" "unprognostic (5.99e-2)" "unprognostic (4.46e-3)" "unprognostic (1.18e-1)" "unprognostic (6.11e-2)" "unprognostic (5.85e-2)" "unprognostic (5.97e-3)" "unprognostic (1.68e-2)" "unprognostic (2.47e-2)" "unprognostic (8.04e-2)" "unprognostic (2.23e-2)" "unprognostic (3.61e-2)" "unprognostic (7.27e-2)" "unprognostic (4.92e-3)" "unprognostic (2.51e-1)" "unprognostic (3.02e-1)" "unprognostic (7.20e-2)" "unprognostic (1.01e-1)" "unprognostic (2.50e-2)" "unprognostic (2.10e-1)" "unprognostic (9.36e-2)" "unprognostic (2.38e-1)" "unprognostic (7.18e-2)" LMNB1 ENSG00000113368 "Lamin B1" P20700 5 126776623-126837020 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Intellectual disability, Leukodystrophy, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 32.1;lymphoid tissue: 45.9" "Cell type enhanced" "Detected in many" "Early spermatids: 104.0;Erythrocyte progenitors: 120.6;Late spermatids: 105.0;Megakaryocyte progenitors: 130.0;Monocyte progenitors: 317.4;Neutrophil progenitors: 112.0;Neutrophils: 536.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005269, HPA050524, CAB079757, CAB079954" Supported Supported "Nuclear membrane" NA NA 860000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 80: Thymus - Adaptive immune response" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 190 "Nuclear membrane" "CAB005269: , CAB079757: , CAB079954: , HPA050524: " "unprognostic (5.50e-3)" "unprognostic (4.08e-2)" "unprognostic (1.31e-1)" "unprognostic (5.78e-2)" "unprognostic (6.22e-2)" "unprognostic (5.91e-2)" "unprognostic (2.73e-1)" "unprognostic (2.01e-2)" "unprognostic (1.84e-2)" "potential prognostic unfavorable (6.99e-4)" "potential prognostic unfavorable (7.95e-7)" "unprognostic (6.87e-3)" "potential prognostic unfavorable (3.77e-9)" "validated prognostic unfavorable (4.21e-6)" "validated prognostic unfavorable (4.52e-7)" "unprognostic (1.11e-3)" "potential prognostic unfavorable (2.05e-5)" "unprognostic (8.02e-3)" "unprognostic (1.42e-1)" "unprognostic (2.66e-1)" "unprognostic (3.43e-2)" "unprognostic (2.19e-3)" "unprognostic (4.26e-2)" "unprognostic (9.45e-3)" "unprognostic (6.48e-2)" "unprognostic (9.47e-2)" "unprognostic (2.17e-2)" "unprognostic (2.37e-2)" "unprognostic (1.91e-1)" "unprognostic (1.01e-1)" "unprognostic (4.04e-1)" LMNB2 LMN2 ENSG00000176619 "Lamin B2" Q03252 19 2427638-2456959 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Epilepsy, Intellectual disability, Neurodegeneration, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 310.2;Extravillous trophoblasts: 98.9;Late primary spermatocytes: 128.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022593, HPA047863, HPA062477" Enhanced Supported "Nuclear membrane" NA NA 79000 "Cluster 29: Non-specific - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 23: Non-specific - Transcription" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 50 "Nuclear membrane" "CAB022593: , HPA047863: , HPA062477: " "unprognostic (4.15e-3)" "unprognostic (1.24e-1)" "unprognostic (7.08e-2)" "unprognostic (1.37e-1)" "unprognostic (1.47e-1)" "unprognostic (1.76e-1)" "unprognostic (2.46e-1)" "unprognostic (6.54e-2)" "unprognostic (3.36e-2)" "unprognostic (2.26e-2)" "unprognostic (1.33e-2)" "unprognostic (1.36e-3)" "unprognostic (5.06e-3)" "validated prognostic unfavorable (1.74e-4)" "validated prognostic unfavorable (3.94e-4)" "potential prognostic unfavorable (5.89e-6)" "unprognostic (1.43e-3)" "unprognostic (1.30e-1)" "unprognostic (2.24e-3)" "unprognostic (1.01e-1)" "unprognostic (2.59e-2)" "unprognostic (6.93e-3)" "unprognostic (2.47e-1)" "potential prognostic unfavorable (2.08e-4)" "unprognostic (3.87e-2)" "unprognostic (1.14e-2)" "unprognostic (6.10e-3)" "unprognostic (6.63e-3)" "unprognostic (2.51e-1)" "unprognostic (1.30e-1)" "unprognostic (1.05e-3)" LMNTD1 "FLJ36004, IFLTD1, Pas1c1" ENSG00000152936 "Lamin tail domain containing 1" Q8N9Z9 12 25409307-25648579 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "fallopian tube: 16.0;testis: 14.1" "Cell type enhanced" "Detected in many" "Bergmann glia: 317.7;Early spermatids: 225.1;Endometrial ciliated cells: 404.5;Ependymal cells: 1131.5;Epididymal efferent duct ciliated cells: 319.0;Fallopian tube ciliated cells: 399.2;Respiratory ciliated cells: 989.7;Retinal pigment epithelial cells: 336.8" "Group enriched" "Detected in many" 7 "Bergmann glia: 334.8;ependymal cell: 1170.2" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 4.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Pancreas - Beta cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA038640 Approved Nucleoplasm,Centrosome NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 34: Ciliated cells - Cilia assembly & function" "Nucleoplasm, Centrosome" "HPA038640: " "unprognostic (4.20e-2)" "unprognostic (8.21e-2)" "unprognostic (1.00e-2)" "unprognostic (1.80e-2)" "unprognostic (1.40e-1)" "unprognostic (9.74e-2)" "unprognostic (2.27e-1)" "unprognostic (1.70e-1)" "unprognostic (1.47e-1)" "unprognostic (4.45e-1)" LMNTD2 "C11orf35, MGC35138" ENSG00000185522 "Lamin tail domain containing 2" Q8IXW0 11 554850-560738 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 23.5;testis: 27.2" "Group enriched" "Detected in many" 7 "Early spermatids: 59.5;Late spermatids: 114.8" "Cell type enhanced" "Detected in many" "deep-layer near-projecting: 6.3;lower rhombic lip: 10.3;upper rhombic lip: 6.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 8.6" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA058474, HPA073912" Uncertain Approved "Cytoplasmic bodies" NA NA "Cluster 21: Testis - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 17 "Cytoplasmic bodies" "HPA058474: , HPA073912: " "unprognostic (3.65e-1)" "unprognostic (4.85e-2)" "unprognostic (3.51e-2)" "unprognostic (1.25e-2)" "unprognostic (1.60e-2)" "unprognostic (4.10e-1)" "unprognostic (2.20e-1)" "unprognostic (5.04e-2)" "unprognostic (2.36e-2)" "unprognostic (7.71e-2)" "unprognostic (1.01e-1)" "unprognostic (4.00e-2)" "unprognostic (1.81e-2)" "unprognostic (2.03e-1)" "unprognostic (1.47e-2)" "unprognostic (3.57e-1)" "unprognostic (1.80e-2)" "unprognostic (7.01e-2)" "unprognostic (8.05e-2)" "unprognostic (2.24e-1)" "unprognostic (7.14e-2)" "potential prognostic unfavorable (1.16e-4)" "unprognostic (4.83e-1)" "unprognostic (3.02e-1)" "unprognostic (1.06e-1)" "unprognostic (2.42e-3)" "unprognostic (3.87e-1)" LMO1 "RBTN1, RHOM1, TTG1" ENSG00000166407 "LIM domain only 1" P25800 11 8224309-8268716 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skeletal muscle: 27.5;tongue: 11.6" "Cell type enhanced" "Detected in some" "Early spermatids: 121.7;Late spermatids: 47.5;Myonuclei: 26.5;Oocytes: 161.2;Pancreatic islet cells: 53.1;Retinal horizontal cells: 64.1;Retinal pigment epithelial cells: 149.2" "Group enriched" "Detected in many" 4 "central nervous system macrophage: 27.4;midbrain-derived inhibitory: 55.9" "Cancer enriched" "Detected in many" 6 "Glioblastoma Multiforme (TCGA): 16.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "Neuroblastoma: 21.5" "Adrenal gland - Adrenal medulla cells, Heart muscle - Cardiomyocytes, Pancreas - Alpha cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 1: Neuronal - Visual perception" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" 100 "unprognostic (3.06e-2)" "unprognostic (3.47e-3)" "unprognostic (1.12e-1)" "unprognostic (1.75e-2)" "unprognostic (6.30e-2)" "unprognostic (3.84e-2)" "unprognostic (6.58e-2)" "unprognostic (9.11e-2)" "unprognostic (3.69e-2)" "unprognostic (8.03e-3)" LMO2 "RBTN2, RBTNL1, RHOM2, TTG2" ENSG00000135363 "LIM domain only 2" P25791 11 33858576-33892076 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ependymal cells: 222.4;Erythrocyte progenitors: 408.7;Hematopoietic stem cells: 208.6;Lymphatic endothelial cells: 262.4;Megakaryocyte progenitors: 213.6;Megakaryocyte-Erythroid progenitors: 385.1;Megakaryocytes: 142.2;Thymic myoid cells: 236.6;Vascular endothelial cells: 146.1" "Cell type enhanced" "Detected in many" "endothelial cell: 455.8;ependymal cell: 231.7" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 32.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 6 "dendritic cells: 1.9;granulocytes: 1.5;monocytes: 1.7" "Group enriched" "Detected in many" 7 "Leukemia: 49.1;lymphoma: 18.5" "Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Colon - Endothelial cells, Minor Salivary Gland - Endothelial cells, Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016258, HPA029285, HPA070901, HPA070910" Approved Approved Nucleoplasm NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 47: Endothelial cells - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 85 Nucleoplasm "CAB016258: , HPA029285: , HPA070901: , HPA070910: " "unprognostic (1.61e-3)" "unprognostic (1.13e-1)" "unprognostic (2.10e-1)" "unprognostic (1.58e-2)" "unprognostic (1.93e-1)" "unprognostic (7.04e-3)" "unprognostic (3.03e-1)" "unprognostic (1.60e-2)" "unprognostic (4.51e-3)" "unprognostic (7.24e-2)" "potential prognostic favorable (5.47e-7)" "unprognostic (6.79e-3)" "unprognostic (2.35e-1)" "unprognostic (6.56e-2)" "potential prognostic favorable (9.50e-4)" "unprognostic (2.96e-3)" "unprognostic (6.83e-3)" "unprognostic (1.44e-1)" "unprognostic (2.26e-1)" "unprognostic (4.09e-1)" "unprognostic (2.01e-2)" "unprognostic (5.03e-3)" "unprognostic (1.66e-1)" "unprognostic (1.49e-1)" "unprognostic (2.29e-1)" "unprognostic (1.47e-1)" "unprognostic (3.57e-1)" "unprognostic (3.62e-1)" "unprognostic (3.40e-1)" "unprognostic (1.17e-1)" "unprognostic (1.68e-1)" LMO3 "DAT1, RBTNL2, Rhom-3" ENSG00000048540 "LIM domain only 3" Q8TAP4 12 16548372-16610594 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 110.4;intestine: 67.4" "Cell type enhanced" "Detected in many" "Adipocytes: 388.0;Alveolar cells type 1: 645.0;Alveolar cells type 2: 545.6;Astrocytes: 401.5;Bergmann glia: 386.0;Ependymal cells: 281.7;Medullary thymic epithelial cells: 412.8;Oligodendrocyte progenitor cells: 176.9;Pituicytes/FSCs: 308.0;Pituitary stem cells: 171.9;Transitional alveolar cells: 472.7" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 128.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 16.5;ovarian cancer: 19.1" "Spleen - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 81: Alveolar cells - Lung function" 21 "unprognostic (1.60e-1)" "unprognostic (1.42e-1)" "unprognostic (1.13e-1)" "unprognostic (5.52e-3)" "unprognostic (1.65e-1)" "unprognostic (3.43e-1)" "unprognostic (1.94e-1)" "unprognostic (1.09e-1)" "unprognostic (3.97e-2)" "unprognostic (7.61e-3)" "unprognostic (5.29e-2)" "unprognostic (5.02e-2)" "unprognostic (2.50e-2)" "unprognostic (1.61e-1)" "unprognostic (3.77e-3)" "unprognostic (1.10e-1)" "unprognostic (1.16e-1)" "unprognostic (5.33e-2)" "unprognostic (1.49e-1)" "unprognostic (7.99e-3)" "unprognostic (1.58e-2)" "unprognostic (1.36e-1)" "unprognostic (1.02e-2)" "potential prognostic unfavorable (3.45e-5)" LMO4 ENSG00000143013 "LIM domain only 4" P61968 1 87328880-87348923 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 239.5" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 457.6;Lacrimal acinar cells: 1216.5" "Cell type enhanced" "Detected in all" "hippocampal CA4: 374.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022345, HPA045877, HPA061638" Approved Approved "Nucleoplasm,Midbody ring,Cytosol" Yes No "Cluster 45: Eosinophils - Unknown function" "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 106 Nucleoplasm "Midbody ring, Cytosol" "CAB022345: , HPA045877: , HPA061638: " "unprognostic (3.11e-1)" "unprognostic (1.66e-1)" "unprognostic (2.47e-1)" "unprognostic (9.18e-2)" "unprognostic (3.42e-1)" "unprognostic (3.50e-2)" "unprognostic (2.38e-1)" "unprognostic (1.66e-3)" "unprognostic (5.07e-3)" "potential prognostic unfavorable (1.21e-5)" "potential prognostic favorable (8.23e-4)" "unprognostic (2.49e-3)" "unprognostic (3.54e-3)" "potential prognostic unfavorable (5.07e-4)" "unprognostic (7.63e-2)" "unprognostic (1.89e-1)" "unprognostic (2.31e-2)" "potential prognostic favorable (5.19e-4)" "unprognostic (1.69e-3)" "unprognostic (2.09e-2)" "unprognostic (1.04e-1)" "unprognostic (7.90e-3)" "unprognostic (1.40e-2)" "unprognostic (6.74e-2)" "unprognostic (8.64e-3)" "unprognostic (8.12e-2)" "unprognostic (5.19e-1)" "unprognostic (8.51e-2)" "unprognostic (4.56e-2)" "unprognostic (6.74e-3)" "unprognostic (6.70e-2)" LMO7 "FBX20, FBXO20, KIAA0858" ENSG00000136153 "LIM domain 7" Q8WWI1 13 75620434-75859870 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 233.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 1487.6;Conjunctival goblet cells: 674.8;Endometrial glandular cells: 761.7;Esophageal apical cells: 2855.7;Ocular epithelial cells: 1277.0;Renal collecting duct intercalated cells: 884.1;Transitional alveolar cells: 753.6;Urothelial cells: 769.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 13.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Lung - Alveolar cells type 1, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "amygdala: 35.2;basal ganglia: 57.1;cerebral cortex: 46.1;hippocampal formation: 59.7" "HPA020923, HPA050184" Enhanced Supported "Actin filaments,Cytosol" NA NA 4500 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 53: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 100: Stratified epithelial cells - Barrier functions" 33 "Actin filaments" Cytosol "HPA020923: , HPA050184: " "unprognostic (2.32e-2)" "unprognostic (3.32e-1)" "unprognostic (2.74e-1)" "unprognostic (3.99e-3)" "unprognostic (3.83e-2)" "unprognostic (1.34e-1)" "unprognostic (8.27e-2)" "unprognostic (7.37e-3)" "unprognostic (2.51e-1)" "unprognostic (8.41e-2)" "validated prognostic favorable (5.77e-9)" "validated prognostic favorable (4.95e-4)" "unprognostic (1.50e-3)" "unprognostic (6.51e-2)" "unprognostic (8.65e-2)" "unprognostic (2.48e-1)" "unprognostic (6.99e-3)" "unprognostic (1.04e-1)" "unprognostic (3.93e-2)" "unprognostic (6.19e-3)" "unprognostic (2.24e-1)" "potential prognostic unfavorable (8.16e-4)" "unprognostic (1.63e-3)" "unprognostic (2.67e-1)" "unprognostic (9.18e-2)" "unprognostic (2.20e-2)" "unprognostic (2.00e-2)" "unprognostic (2.35e-1)" "unprognostic (1.40e-1)" "unprognostic (2.97e-1)" "unprognostic (4.59e-2)" LMOD1 "1D, 64kD, D1, SM-LMOD, SMLMOD" ENSG00000163431 "Leiomodin 1" P29536 1 201896456-201946588 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 897.6;intestine: 491.1" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 205.8;Cone photoreceptor cells: 455.4;Decidual stromal cells: 194.1;Hepatic stellate cells: 193.6;Leydig cells: 249.6;Pericytes: 320.7;Peritubular myoid cells: 413.2;Rod photoreceptor cells: 253.3;Salivary myoepithelial cells: 167.0;Smooth muscle cells: 698.6;Vascular smooth muscle cells: 812.0" "Cell type enriched" "Detected in many" 5 "vascular associated smooth muscle cell: 416.3" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 64.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "testis cancer: 8.7" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Heart muscle - Smooth muscle cells, Kidney - Fibroblasts, Lung - Smooth muscle cells, Minor Salivary Gland - Smooth muscle cells, Prostate - Smooth muscle cells, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA028325, HPA028435, HPA030097" Enhanced Approved Cytosol No No "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 1 Cytosol "HPA028325: , HPA028435: , HPA030097: " "unprognostic (2.84e-3)" "unprognostic (2.10e-2)" "unprognostic (4.51e-1)" "unprognostic (2.59e-1)" "unprognostic (2.33e-2)" "unprognostic (1.11e-2)" "unprognostic (1.74e-1)" "unprognostic (2.87e-1)" "unprognostic (1.14e-1)" "unprognostic (1.84e-2)" "validated prognostic favorable (3.87e-4)" "validated prognostic favorable (1.24e-4)" "potential prognostic unfavorable (1.34e-6)" "potential prognostic favorable (1.01e-5)" "unprognostic (1.00e-2)" "unprognostic (1.42e-1)" "unprognostic (4.49e-1)" "unprognostic (6.11e-3)" "unprognostic (5.86e-2)" "unprognostic (2.84e-3)" "unprognostic (4.42e-3)" "unprognostic (3.47e-1)" "unprognostic (1.85e-3)" "unprognostic (9.01e-2)" "unprognostic (4.78e-2)" "unprognostic (1.58e-2)" "unprognostic (4.92e-2)" "unprognostic (2.29e-2)" "unprognostic (1.70e-1)" "unprognostic (5.01e-3)" "unprognostic (5.14e-3)" LMOD2 ENSG00000170807 "Leiomodin 2" Q6P5Q4 7 123655866-123664290 "Disease related genes, Predicted intracellular proteins" Actin-binding "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 39 "heart muscle: 728.6;skeletal muscle: 874.4;tongue: 741.3" "Group enriched" "Detected in some" 15 "Cardiomyocytes: 141.5;Myonuclei: 448.3;Thymic myoid cells: 558.8" "Cell type enhanced" "Detected in single" "ependymal cell: 1.7" "Group enriched" "Detected in some" 18 "Head and Neck Squamous Cell Carcinoma (TCGA): 6.3;Prostate Adenocarcinoma (TCGA): 2.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA046370, HPA051039" Enhanced Uncertain "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 41: Striated muscle - Muscle contraction" "Cluster 29: Forebrain - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 46: Skeletal myocytes - Muscle structure & formation" "Plasma membrane" "Actin filaments, Cytosol" "HPA046370: , HPA051039: " "unprognostic (5.07e-3)" "unprognostic (1.63e-1)" LMOD3 ENSG00000163380 "Leiomodin 3" Q0VAK6 3 69106065-69123032 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Nemaline myopathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 104.1;skeletal muscle: 430.5;tongue: 213.1" "Group enriched" "Detected in many" 9 "Myonuclei: 241.8;Oocytes: 345.4;Thymic myoid cells: 417.4" "Cell type enhanced" "Detected in many" "pericyte: 11.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Pituitary gland - Gonadotropes, Prostate - Fibroblasts, Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA036034 Uncertain NA NA "Cluster 32: Basophils - Transcription" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 1 "HPA036034: " "unprognostic (1.77e-2)" "unprognostic (2.56e-2)" "unprognostic (3.27e-2)" "unprognostic (4.61e-2)" "unprognostic (2.55e-1)" "unprognostic (1.38e-1)" LMTK2 "AATYK2, BREK, cprk, KIAA1079, KPI-2, KPI2, LMR2, PPP1R100" ENSG00000164715 "Lemur tyrosine kinase 2" Q8IWU2 7 98106862-98209638 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 330.9;Neutrophils: 487.5;Urothelial cells: 552.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Lung - Alveolar cells type 1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010657, HPA041836" Uncertain Approved "Nuclear speckles,Plasma membrane,Centriolar satellite,Cytosol" NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 11 "Nuclear speckles, Centriolar satellite" "Plasma membrane, Cytosol" "HPA010657: , HPA041836: " "unprognostic (1.84e-1)" "unprognostic (1.40e-2)" "unprognostic (2.98e-1)" "unprognostic (8.57e-2)" "unprognostic (2.21e-1)" "unprognostic (3.49e-2)" "unprognostic (5.60e-2)" "unprognostic (3.27e-2)" "unprognostic (1.68e-1)" "potential prognostic unfavorable (2.58e-4)" "potential prognostic favorable (5.00e-9)" "unprognostic (1.52e-3)" "unprognostic (6.41e-2)" "unprognostic (5.18e-3)" "unprognostic (1.98e-2)" "unprognostic (1.92e-1)" "unprognostic (2.20e-1)" "unprognostic (9.11e-2)" "unprognostic (2.63e-2)" "potential prognostic unfavorable (6.67e-4)" "unprognostic (1.78e-1)" "unprognostic (3.75e-1)" "unprognostic (3.81e-1)" "unprognostic (3.87e-1)" "unprognostic (1.56e-1)" "unprognostic (1.13e-1)" "unprognostic (3.00e-1)" "unprognostic (3.25e-1)" "unprognostic (4.16e-1)" "unprognostic (2.20e-2)" "unprognostic (7.13e-2)" LMTK3 "KIAA1883, LMR3, PPP1R101, TYKLM3" ENSG00000142235 "Lemur tyrosine kinase 3" Q96Q04 19 48485271-48513935 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 59.1;pituitary gland: 17.5" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 72.5;Breast secretory cells: 84.6;Rod photoreceptor cells: 221.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enteroendocrine cells, Lung - Alveolar cells type 2, Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040203, HPA077070" Enhanced Supported Uncertain "Nucleoplasm,Cell Junctions" NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" 12 Nucleoplasm "Cell Junctions" "HPA040203: , HPA077070: " "unprognostic (1.00e-1)" "unprognostic (1.28e-1)" "unprognostic (1.39e-1)" "unprognostic (1.11e-1)" "unprognostic (1.97e-2)" "unprognostic (2.29e-1)" "unprognostic (2.73e-1)" "unprognostic (3.68e-1)" "unprognostic (2.01e-1)" "unprognostic (3.04e-2)" "unprognostic (2.01e-3)" "unprognostic (6.74e-2)" "potential prognostic favorable (2.89e-4)" "unprognostic (1.29e-1)" "unprognostic (1.09e-1)" "unprognostic (2.53e-1)" "unprognostic (1.65e-1)" "potential prognostic favorable (3.63e-4)" "potential prognostic unfavorable (4.62e-4)" "unprognostic (2.61e-1)" "unprognostic (7.14e-2)" "unprognostic (5.20e-3)" "unprognostic (2.41e-1)" "unprognostic (1.56e-2)" "unprognostic (3.53e-2)" "unprognostic (3.94e-2)" "unprognostic (1.14e-1)" "unprognostic (7.20e-2)" "unprognostic (8.88e-2)" "unprognostic (9.99e-2)" LMX1A "LMX1, LMX1.1" ENSG00000162761 "LIM homeobox transcription factor 1 alpha" Q8TE12 1 165201867-165356715 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "choroid plexus: 19.2" "Group enriched" "Detected in some" 7 "Choroid plexus epithelial cells: 570.4;Corticotrophs: 711.3;Neuroendocrine cells: 250.1" "Cell type enriched" "Detected in some" 27 "choroid plexus epithelial cell: 452.3" "Cancer enhanced" "Detected in single" "Testicular Germ Cell Tumor (TCGA): 1.0" "Region enriched" "Detected in many" 9 "choroid plexus: 43.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 1.0;Gastric cancer: 1.0" "Minor Salivary Gland - Fibroblasts, Pituitary gland - Corticotropes, Stomach - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA030088 Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" 5 "Nucleoplasm, Golgi apparatus, Vesicles" "HPA030088: " "unprognostic (2.42e-1)" LMX1B NPS1 ENSG00000136944 "LIM homeobox transcription factor 1 beta" O60663 9 126613928-126701032 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "salivary gland: 17.5" "Cell type enhanced" "Detected in some" "Breast hormone-responsive cells: 23.5;Breast myoepithelial cells: 29.3;Breast secretory cells: 19.0;Lacrimal acinar cells: 77.9;Podocytes: 268.7;Salivary acinar cells: 58.4;Salivary myoepithelial cells: 18.4" "Group enriched" "Detected in some" 5 "ependymal cell: 14.6;splatter: 13.4" "Cancer enriched" "Detected in some" 14 "Breast Invasive Carcinoma (TCGA): 18.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 6.5;Rhabdoid: 7.4" "Colon - Enteric glia cells, Kidney - Podocytes, Minor Salivary Gland - Minor salivary gland ductal cells, Pituitary gland - Gonadotropes, Skin - Eccrine sweat gland cells, Testis - Spermatogonia" "Region enhanced" "Detected in some" "pons and medulla: 2.3" "Region enhanced" "Detected in many" "midbrain: 5.8" "HPA073716, HPA075656" Approved Nucleoplasm NA NA "Cluster 82: Salivary gland - Secretion" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 27: Breast cancer - Unknown function" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 6 Nucleoplasm "HPA073716: , HPA075656: " "unprognostic (3.71e-1)" "unprognostic (1.57e-1)" "unprognostic (1.33e-1)" "unprognostic (1.40e-1)" LNP1 NP3 ENSG00000206535 "Leukemia NUP98 fusion partner 1" A1A4G5 3 100401532-100456319 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 42.7;testis: 27.1" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 89.0;Early spermatids: 136.7;Late primary spermatocytes: 243.0;Retinal amacrine cells: 47.3;Retinal bipolar cells: 49.3;Retinal horizontal cells: 216.4;Rod photoreceptor cells: 62.5" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Renal Papillary Cell Carcinoma (TCGA): 18.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.4" "Lineage enriched" "Detected in single" 4 "T-cells: 1.4" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Liver - Hepatocytes, Lung - Fibroblasts_1, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "amygdala: 9.7;cerebral cortex: 12.3;hippocampal formation: 10.4;olfactory bulb: 7.3" HPA047926 Approved "Nuclear speckles,Vesicles,Cytosol" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 20: Myeloma - Immune response" "Cluster 109: Neurons - Neuronal signaling" 8 Vesicles "Nuclear speckles, Cytosol" "HPA047926: " "unprognostic (1.44e-1)" "unprognostic (2.64e-2)" "unprognostic (7.97e-2)" "unprognostic (1.76e-2)" "unprognostic (3.29e-3)" "unprognostic (1.05e-1)" "unprognostic (1.46e-1)" "unprognostic (3.45e-3)" "unprognostic (1.82e-1)" "unprognostic (2.61e-1)" "unprognostic (3.25e-2)" "unprognostic (4.71e-1)" "potential prognostic favorable (8.57e-4)" "unprognostic (6.14e-2)" "unprognostic (1.18e-1)" "unprognostic (1.74e-2)" "unprognostic (1.14e-1)" "unprognostic (1.68e-3)" "unprognostic (1.68e-2)" "unprognostic (2.27e-2)" "unprognostic (2.41e-1)" "unprognostic (1.71e-2)" "unprognostic (3.22e-1)" "unprognostic (8.95e-2)" "unprognostic (1.22e-2)" "unprognostic (6.13e-2)" "unprognostic (4.85e-3)" "unprognostic (1.19e-1)" "unprognostic (2.41e-1)" "unprognostic (1.43e-1)" "unprognostic (1.35e-1)" LNPEP "CAP, IRAP, P-LAP, PLAP" ENSG00000113441 "Leucyl and cystinyl aminopeptidase" Q9UIQ6 5 96935394-97037513 "Enzymes, Predicted membrane proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 403.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043642 Approved "Intracellular and membrane" Enzyme NA NA 8900000 "Cluster 32: Basophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 28 "HPA043642: " "potential prognostic favorable (2.80e-4)" "unprognostic (1.80e-1)" "unprognostic (3.87e-2)" "unprognostic (8.67e-2)" "unprognostic (2.03e-1)" "unprognostic (6.89e-2)" "unprognostic (1.36e-1)" "unprognostic (5.08e-2)" "unprognostic (1.70e-3)" "unprognostic (1.12e-1)" "potential prognostic favorable (4.71e-4)" "unprognostic (1.25e-2)" "unprognostic (1.05e-1)" "unprognostic (4.42e-2)" "unprognostic (1.59e-1)" "unprognostic (2.09e-1)" "unprognostic (1.05e-2)" "unprognostic (9.42e-2)" "unprognostic (6.22e-2)" "unprognostic (5.69e-3)" "potential prognostic unfavorable (1.67e-4)" "unprognostic (2.85e-2)" "unprognostic (1.34e-1)" "unprognostic (1.65e-2)" "unprognostic (4.69e-2)" "unprognostic (6.89e-2)" "unprognostic (1.42e-1)" "unprognostic (4.48e-2)" "unprognostic (3.04e-1)" "unprognostic (3.46e-2)" "unprognostic (4.37e-2)" LNPK "KIAA1715, LNP, LNP1, Ul" ENSG00000144320 "Lunapark, ER junction formation factor" Q9C0E8 2 175923882-176002839 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Developmental protein" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 305.1;Myonuclei: 221.0;Neutrophil progenitors: 339.9;Thymic myoid cells: 197.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014205 Approved Supported "Nucleoplasm,Endoplasmic reticulum,Connecting piece,Mid piece,Principal piece,End piece" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 40: Non-specific - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 24 "Endoplasmic reticulum" "Nucleoplasm, Connecting piece, Mid piece, Principal piece, End piece" "HPA014205: " "unprognostic (6.39e-2)" "unprognostic (2.76e-2)" "unprognostic (1.80e-3)" "unprognostic (1.16e-1)" "unprognostic (1.58e-2)" "unprognostic (3.04e-1)" "potential prognostic unfavorable (5.59e-4)" "unprognostic (7.60e-2)" "potential prognostic unfavorable (3.73e-4)" "potential prognostic favorable (2.88e-5)" "unprognostic (5.78e-2)" "unprognostic (1.40e-3)" "unprognostic (2.89e-3)" "unprognostic (1.47e-2)" "unprognostic (6.47e-3)" "unprognostic (2.27e-1)" "unprognostic (1.22e-2)" "unprognostic (7.61e-3)" "potential prognostic unfavorable (4.38e-4)" "unprognostic (1.38e-2)" "unprognostic (1.01e-2)" "unprognostic (1.14e-1)" "unprognostic (2.45e-1)" "unprognostic (7.66e-3)" "unprognostic (1.51e-3)" "unprognostic (2.88e-1)" "unprognostic (4.30e-2)" "potential prognostic unfavorable (7.17e-4)" "unprognostic (2.67e-1)" LNX1 "LNX, MPDZ, PDZRN2" ENSG00000072201 "Ligand of numb-protein X 1" Q8TBB1 4 53459301-53701405 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 252.4;Early spermatids: 246.9;Endometrial ciliated cells: 291.1;Endometrial glandular cells: 998.6;Endometrial luminal cells: 500.4;Esophageal apical cells: 652.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002235, HPA071091" Approved Supported "Cell Junctions,Cytosol" "Intracellular and membrane" Enzyme NA NA "Cluster 63: Non-specific - Basic cellular processes" "Cluster 53: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 51: Secretory epithelial cells - Mixed function" 380 "Cell Junctions" Cytosol "HPA002235: , HPA071091: " "unprognostic (2.04e-1)" "unprognostic (1.89e-2)" "unprognostic (1.92e-1)" "unprognostic (2.78e-1)" "unprognostic (7.21e-2)" "unprognostic (1.32e-1)" "unprognostic (4.98e-1)" "unprognostic (2.15e-1)" "unprognostic (2.45e-1)" "unprognostic (1.44e-2)" "potential prognostic favorable (7.08e-8)" "unprognostic (5.70e-3)" "unprognostic (1.88e-2)" "unprognostic (1.21e-1)" "unprognostic (7.06e-3)" "unprognostic (7.69e-2)" "unprognostic (3.27e-1)" "unprognostic (5.23e-2)" "unprognostic (9.56e-2)" "unprognostic (1.89e-1)" "unprognostic (1.77e-1)" "unprognostic (5.15e-2)" "unprognostic (8.37e-2)" "unprognostic (3.70e-2)" "unprognostic (2.54e-3)" "potential prognostic unfavorable (9.89e-4)" "unprognostic (4.86e-2)" "unprognostic (2.83e-1)" "unprognostic (5.36e-2)" "unprognostic (1.27e-1)" "unprognostic (8.50e-2)" LNX2 "MGC46315, PDZRN1" ENSG00000139517 "Ligand of numb-protein X 2" Q8N448 13 27545913-27620529 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 210.1;Alveolar cells type 2: 208.2;Podocytes: 243.9;Transitional alveolar cells: 185.3" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 139.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate basal glandular cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA040698 Approved Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 60: Stomach - Digestion" "Cluster 5: Non-specific - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 81: Alveolar cells - Lung function" 96 Vesicles "Plasma membrane, Cytosol" "HPA040698: " "unprognostic (4.14e-3)" "unprognostic (3.84e-2)" "unprognostic (3.14e-2)" "unprognostic (2.33e-3)" "unprognostic (1.72e-2)" "unprognostic (8.32e-2)" "unprognostic (1.59e-1)" "unprognostic (8.12e-2)" "unprognostic (1.06e-1)" "unprognostic (1.82e-1)" "validated prognostic favorable (1.80e-10)" "validated prognostic favorable (4.50e-4)" "potential prognostic favorable (3.60e-4)" "unprognostic (5.91e-2)" "unprognostic (3.02e-2)" "unprognostic (3.29e-3)" "unprognostic (1.54e-1)" "unprognostic (1.64e-2)" "unprognostic (1.80e-1)" "unprognostic (5.40e-2)" "unprognostic (2.51e-2)" "unprognostic (2.45e-2)" "unprognostic (1.36e-3)" "unprognostic (9.69e-2)" "unprognostic (9.22e-2)" "unprognostic (6.80e-2)" "unprognostic (2.05e-1)" "unprognostic (6.04e-2)" "unprognostic (1.84e-1)" "unprognostic (5.34e-1)" "unprognostic (8.35e-2)" LONP1 "hLON, LonHS, PIM1, PRSS15" ENSG00000196365 "Lon peptidase 1, mitochondrial" P36776 19 5691834-5720572 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA-binding, Hydrolase, Protease, Serine protease" "Cataract, Deafness, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 190.0" "Cell type enhanced" "Detected in many" "Epicardial cells: 118.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002034, HPA002192" Supported Supported Nucleoplasm,Mitochondria,Cytosol No No 52000 "Cluster 18: Non-specific - Translation" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 45: Non-specific - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 65: Non-specific - Cell growth & division" 84 Mitochondria "Nucleoplasm, Cytosol" "HPA002034: , HPA002192: " "unprognostic (1.30e-2)" "unprognostic (9.59e-2)" "unprognostic (3.97e-1)" "unprognostic (2.05e-1)" "unprognostic (3.61e-1)" "unprognostic (3.51e-1)" "unprognostic (4.10e-2)" "unprognostic (3.59e-2)" "unprognostic (2.61e-2)" "unprognostic (1.74e-2)" "unprognostic (2.63e-1)" "unprognostic (1.13e-1)" "unprognostic (2.32e-1)" "potential prognostic unfavorable (3.27e-4)" "unprognostic (3.34e-3)" "unprognostic (1.50e-1)" "unprognostic (4.72e-3)" "unprognostic (3.68e-3)" "unprognostic (1.49e-2)" "unprognostic (1.53e-1)" "unprognostic (3.35e-2)" "unprognostic (1.05e-1)" "unprognostic (1.24e-1)" "unprognostic (5.95e-2)" "unprognostic (2.39e-1)" "unprognostic (3.60e-3)" "unprognostic (2.13e-1)" "unprognostic (1.82e-2)" "unprognostic (7.18e-3)" "unprognostic (1.21e-1)" "unprognostic (3.13e-2)" LONP2 "LONP, LONPL, MGC4840" ENSG00000102910 "Lon peptidase 2, peroxisomal" Q86WA8 16 48244300-48363122 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008862 Uncertain NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 31: Non-specific - Transcription" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 14 "HPA008862: " "unprognostic (1.97e-1)" "unprognostic (4.55e-3)" "unprognostic (2.05e-1)" "unprognostic (1.41e-3)" "unprognostic (3.70e-2)" "unprognostic (7.98e-2)" "unprognostic (1.73e-1)" "unprognostic (1.51e-2)" "unprognostic (2.16e-2)" "unprognostic (1.74e-2)" "potential prognostic favorable (7.80e-5)" "unprognostic (5.45e-2)" "unprognostic (1.86e-2)" "unprognostic (2.80e-2)" "unprognostic (3.10e-3)" "unprognostic (4.76e-2)" "unprognostic (1.96e-1)" "unprognostic (5.67e-2)" "unprognostic (1.50e-1)" "unprognostic (4.25e-1)" "unprognostic (1.11e-2)" "unprognostic (6.91e-2)" "unprognostic (4.03e-1)" "unprognostic (3.18e-1)" "unprognostic (9.59e-2)" "unprognostic (2.29e-1)" "unprognostic (9.31e-2)" "unprognostic (3.73e-2)" "unprognostic (2.49e-1)" "unprognostic (8.82e-2)" "unprognostic (1.00e-1)" LONRF1 "FLJ23749, RNF191" ENSG00000154359 "LON peptidase N-terminal domain and ring finger 1" Q17RB8 8 12721906-12756073 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bergmann glia: 97.0;Brain excitatory neurons: 59.6;Brain inhibitory neurons: 60.6;Choroid plexus epithelial cells: 51.2;Distal convoluted tubule cells: 54.4;Early spermatids: 42.9;Late spermatids: 47.3;Loop of henle epithelial cells: 43.9;Oligodendrocyte progenitor cells: 50.2;Other brain neurons: 44.8;Podocytes: 86.5;Proximal tubule cells: 43.1;Renal collecting duct intercalated cells: 48.5;Renal connecting tubule cells: 50.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Bone cancer: 24.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023584, HPA024814" Uncertain Approved "Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 47: Testis - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 105: Non-specific - Mixed function" 81 "Plasma membrane, Cytosol" Centrosome "HPA023584: , HPA024814: " "unprognostic (1.09e-1)" "unprognostic (1.09e-1)" "potential prognostic favorable (4.76e-6)" "unprognostic (4.07e-2)" "unprognostic (4.95e-2)" "unprognostic (2.67e-1)" "unprognostic (3.60e-1)" "unprognostic (2.73e-1)" "unprognostic (5.03e-2)" "unprognostic (6.37e-2)" "potential prognostic favorable (6.26e-5)" "unprognostic (4.52e-3)" "unprognostic (3.90e-1)" "unprognostic (6.66e-3)" "unprognostic (6.32e-2)" "unprognostic (3.77e-2)" "unprognostic (2.55e-1)" "unprognostic (1.24e-2)" "unprognostic (2.32e-1)" "unprognostic (1.23e-1)" "unprognostic (2.57e-2)" "unprognostic (1.78e-1)" "unprognostic (1.66e-1)" "unprognostic (1.89e-2)" "unprognostic (7.20e-2)" "unprognostic (1.40e-1)" "unprognostic (4.22e-1)" "unprognostic (1.24e-1)" "potential prognostic unfavorable (7.13e-4)" "unprognostic (4.09e-2)" LONRF2 "FLJ45273, RNF192" ENSG00000170500 "LON peptidase N-terminal domain and ring finger 2" Q1L5Z9 2 100271875-100322501 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 39.8;fallopian tube: 40.8" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 455.1;Brain inhibitory neurons: 221.4;Epididymal principal cells: 270.0;Gonadotrophs: 289.5;Lactotrophs: 249.1;Pituicytes/FSCs: 1795.6;Somatotrophs: 342.3" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 4 "Thyroid Carcinoma (TCGA): 20.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034595, HPA057366" Approved Approved Nucleoplasm NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 15 Nucleoplasm "HPA034595: , HPA057366: " "unprognostic (1.87e-1)" "unprognostic (5.62e-3)" "unprognostic (2.83e-2)" "unprognostic (1.65e-1)" "unprognostic (1.57e-3)" "unprognostic (3.59e-2)" "unprognostic (1.82e-2)" "unprognostic (1.12e-1)" "potential prognostic favorable (2.87e-4)" "unprognostic (2.36e-1)" "unprognostic (9.58e-2)" "potential prognostic favorable (8.59e-4)" "unprognostic (5.64e-2)" "unprognostic (1.47e-2)" "unprognostic (6.52e-2)" "unprognostic (2.36e-1)" LONRF3 "FLJ22612, RNF127" ENSG00000175556 "LON peptidase N-terminal domain and ring finger 3" Q496Y0 X 118974614-119018355 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 132.6;Endometrial glandular cells: 135.5;Epididymal basal cells: 142.9;Epididymal efferent duct absorptive cells: 105.3;monocytes: 159.7;Salivary acinar cells: 89.2" "Cell type enhanced" "Detected in many" "fibroblast: 76.1;hippocampal dentate gyrus: 54.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 3.8" "Lineage enriched" "Detected in single" 7 "T-cells: 3.8" "Low cancer specificity" "Detected in many" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050422, HPA061162" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 35: Non-specific - DNA binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 8 Nucleoplasm "Plasma membrane" "HPA050422: , HPA061162: " "unprognostic (5.45e-2)" "unprognostic (7.67e-3)" "unprognostic (1.51e-1)" "unprognostic (3.69e-3)" "unprognostic (5.25e-2)" "unprognostic (1.03e-2)" "validated prognostic favorable (1.03e-5)" "validated prognostic favorable (4.66e-4)" "unprognostic (5.58e-2)" "unprognostic (4.13e-3)" "unprognostic (2.25e-1)" "unprognostic (1.26e-1)" "unprognostic (3.59e-1)" "unprognostic (7.26e-2)" "unprognostic (1.89e-3)" "unprognostic (2.13e-1)" "unprognostic (1.33e-1)" "unprognostic (4.53e-3)" "unprognostic (3.58e-1)" "unprognostic (8.22e-2)" "unprognostic (1.44e-1)" "unprognostic (2.54e-2)" LORICRIN LOR ENSG00000203782 "Loricrin cornified envelope precursor protein" P23490 1 153259687-153262124 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Keratinization "Ichthyosis, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 39 "skin 1: 1773.2" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 2.6;Brain inhibitory neurons: 1.9;cDC: 4.7;Esophageal apical cells: 3.2;Esophageal suprabasal cells: 1.8;Granulosa cells: 2.4;Oligodendrocyte progenitor cells: 5.1;Other brain neurons: 5.8;Ovarian stromal cells: 4.0;Retinal amacrine cells: 4.8;Suprabasal keratinocytes: 2.3" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in some" 14 "Skin Cutaneous Melanoma (TCGA): 88.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "lymphoma: 1.9" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in many" "HPA076123, HPA077266" Enhanced NA NA 1700000 "Cluster 9: Skin - Hair follicle development" "Cluster 1: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 98: Neurons - Neurotransmission & signaling" 7 "HPA076123: , HPA077266: " "unprognostic (2.94e-1)" "unprognostic (3.89e-3)" "potential prognostic favorable (6.62e-5)" "unprognostic (5.72e-2)" "unprognostic (7.09e-2)" LOX ENSG00000113083 "Lysyl oxidase" P28300 5 122063195-122078413 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Aortic aneurysm, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 32.0;Early spermatids: 40.5;Endometrial secretory cells: 35.0;Endometrial stromal cells: 34.2;Ependymal cells: 32.8;Extravillous trophoblasts: 65.5;Fibroblasts: 111.6;Hepatic stellate cells: 58.1;Late primary spermatocytes: 32.7;Lymphatic endothelial cells: 95.6;Peritubular myoid cells: 35.7;Podocytes: 68.1" "Cell type enriched" "Detected in some" 4 "ependymal cell: 40.4" "Cancer enriched" "Detected in all" 4 "Kidney Renal Clear Cell Carcinoma (TCGA): 79.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 80.9;Kidney cancer: 81.9" "Adrenal gland - Fibroblasts, Heart muscle - Fibroblasts, Skin - Fibroblasts_2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA043930 Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" Enzyme NA NA 280000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 46: Brainstem - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 10 "Endoplasmic reticulum" "HPA043930: " "unprognostic (2.08e-2)" "unprognostic (2.88e-1)" "unprognostic (2.14e-2)" "unprognostic (1.40e-2)" "unprognostic (2.41e-2)" "unprognostic (2.42e-1)" "unprognostic (7.04e-3)" "potential prognostic unfavorable (6.26e-5)" "unprognostic (2.68e-1)" "potential prognostic unfavorable (5.24e-4)" "unprognostic (1.86e-2)" "unprognostic (1.12e-1)" "potential prognostic unfavorable (8.95e-4)" "potential prognostic unfavorable (3.90e-4)" "unprognostic (2.43e-2)" "unprognostic (9.81e-3)" "potential prognostic unfavorable (9.13e-6)" "unprognostic (5.07e-2)" "unprognostic (3.85e-2)" "unprognostic (2.27e-2)" "potential prognostic unfavorable (1.64e-4)" "unprognostic (1.31e-2)" "unprognostic (7.63e-3)" "unprognostic (1.29e-1)" "unprognostic (6.13e-2)" "unprognostic (1.05e-1)" "unprognostic (1.22e-2)" "potential prognostic unfavorable (4.42e-4)" "unprognostic (1.44e-1)" "unprognostic (2.56e-2)" "unprognostic (6.43e-2)" LOXHD1 "DFNB77, FLJ32670, LH2D1" ENSG00000167210 "Lipoxygenase homology PLAT domains 1" Q8IVV2 18 46476972-46657220 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hearing "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 6.8;testis: 21.5" "Cell type enhanced" "Detected in some" "Early spermatids: 365.4;Lactotrophs: 74.4;Late primary spermatocytes: 89.8;Late spermatids: 1054.5;Mesothelial cells: 72.2;Neutrophil progenitors: 147.6;Neutrophils: 199.7;Thyrotrophs: 98.5" "Cell type enhanced" "Detected in many" "eccentric medium spiny neuron: 53.4;medium spiny neuron: 51.1" "Group enriched" "Detected in some" 5 "Kidney Chromophobe (TCGA): 1.8;Testicular Germ Cell Tumor (TCGA): 1.9" "Region enhanced" "Detected in many" "basal ganglia: 7.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 38 "Bone cancer: 49.3" "Pituitary gland - Lactotropes, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA077128 Approved "Plasma membrane" NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 33: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 48: Neutrophils - Phagocytosis & degranulation" "Plasma membrane" "HPA077128: " "unprognostic (6.30e-3)" "unprognostic (2.42e-1)" "unprognostic (1.20e-1)" LOXL1 "LOL, LOXL" ENSG00000129038 "Lysyl oxidase like 1" Q08397 15 73925989-73952137 "Disease related genes, Plasma proteins, Predicted secreted proteins" Oxidoreductase Glaucoma "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 67.3" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 164.7;Extravillous trophoblasts: 245.8;Fibroblasts: 60.4;Hepatic stellate cells: 213.0;Podocytes: 58.8;Retinal pigment epithelial cells: 85.3;Smooth muscle cells: 53.3" "Group enriched" "Detected in many" 6 "choroid plexus epithelial cell: 120.7;fibroblast: 31.9" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "choroid plexus: 26.2" "Immune cell enhanced" "Detected in some" "T-reg: 3.4" "Lineage enriched" "Detected in single" 34 "T-cells: 3.4" "Cancer enhanced" "Detected in many" "Brain cancer: 89.2" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Adrenal gland - Fibroblasts, Liver - Hepatic stellate cells, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Testis - Early spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA042111, HPA063583" Approved Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" Enzyme No No 130000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 2 "Endoplasmic reticulum" "HPA042111: , HPA063583: " "unprognostic (1.44e-2)" "unprognostic (8.54e-2)" "unprognostic (2.26e-1)" "unprognostic (4.83e-3)" "unprognostic (1.92e-2)" "unprognostic (1.31e-1)" "validated prognostic unfavorable (2.00e-4)" "validated prognostic unfavorable (2.00e-4)" "unprognostic (1.75e-1)" "unprognostic (3.49e-1)" "validated prognostic unfavorable (3.76e-5)" "validated prognostic unfavorable (1.57e-4)" "unprognostic (9.91e-3)" "unprognostic (1.60e-1)" "unprognostic (2.08e-2)" "unprognostic (2.94e-2)" "unprognostic (1.19e-1)" "unprognostic (3.24e-1)" "unprognostic (1.43e-1)" "unprognostic (5.60e-2)" "unprognostic (3.59e-2)" "unprognostic (1.58e-1)" "unprognostic (2.29e-1)" "unprognostic (1.52e-1)" "unprognostic (2.87e-1)" "unprognostic (2.70e-2)" "unprognostic (3.46e-2)" "unprognostic (4.63e-2)" "unprognostic (2.25e-2)" "unprognostic (2.34e-3)" "unprognostic (4.63e-1)" LOXL2 "LOR, WS9-14" ENSG00000134013 "Lysyl oxidase like 2" Q9Y4K0 8 23296897-23425328 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Transcription, Transcription regulation" "Chromatin regulator, Oxidoreductase, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 38.5" "Cell type enhanced" "Detected in many" "Adipocytes: 77.1;Breast myoepithelial cells: 71.5;Endometrial stromal cells: 72.4;Fibro-adipogenic progenitors: 76.0;Fibroblasts: 72.6;Hepatic stellate cells: 264.6;Oocytes: 322.4;Ovarian stromal cells: 99.1;Pericytes: 117.7;Smooth muscle cells: 101.7;Vascular endothelial cells: 93.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Kidney cancer: 665.7" "Liver - Vascular endothelial cells, Prostate - Smooth muscle cells, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" "CAB025848, HPA036257, HPA056542" Approved Enhanced Nucleoplasm "Secreted to extracellular matrix" Transcription NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 49: Hindbrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 41 Nucleoplasm "CAB025848: , HPA036257: , HPA056542: " "unprognostic (1.49e-1)" "unprognostic (1.73e-1)" "unprognostic (2.53e-2)" "potential prognostic unfavorable (4.72e-4)" "unprognostic (3.63e-2)" "unprognostic (6.19e-2)" "unprognostic (8.40e-3)" "unprognostic (1.29e-1)" "unprognostic (2.95e-2)" "unprognostic (4.10e-2)" "unprognostic (3.77e-2)" "potential prognostic unfavorable (1.58e-4)" "unprognostic (2.56e-2)" "unprognostic (2.24e-3)" "unprognostic (1.40e-1)" "validated prognostic unfavorable (9.74e-7)" "validated prognostic unfavorable (1.68e-5)" "unprognostic (3.81e-3)" "unprognostic (3.28e-3)" "unprognostic (1.48e-3)" "potential prognostic unfavorable (4.38e-4)" "potential prognostic unfavorable (6.91e-4)" "unprognostic (1.48e-1)" "unprognostic (2.69e-1)" "unprognostic (3.28e-1)" "unprognostic (8.33e-2)" "unprognostic (1.59e-1)" "unprognostic (3.61e-2)" "unprognostic (1.67e-1)" "unprognostic (7.36e-3)" "unprognostic (2.00e-1)" LOXL3 ENSG00000115318 "Lysyl oxidase like 3" P58215 2 74532258-74555690 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Inflammatory response" Oxidoreductase "Deafness, Stickler syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 31.9;Epicardial cells: 45.5;Fibro-adipogenic progenitors: 23.8;Hofbauer cells: 35.3;Kupffer cells: 27.7;Macrophages: 40.8;Microglia: 83.6;Müller glia: 36.9;Neutrophil progenitors: 30.9;Platelets: 25.3" "Cell type enriched" "Detected in many" 4 "central nervous system macrophage: 111.4" "Group enriched" "Detected in many" 4 "Glioblastoma Multiforme (TCGA): 20.9;Skin Cutaneous Melanoma (TCGA): 48.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 11.7;non-classical monocyte: 9.3" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Rhabdoid: 94.7;skin cancer: 164.6" "Colon - Enteric glia cells, Heart muscle - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035281 Approved "Secreted to extracellular matrix" Enzyme NA NA 540000 "Cluster 40: Monocytes - Innate immune response" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 69: Skin cancer - ECM organization" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" "HPA035281: " "unprognostic (1.01e-1)" "unprognostic (1.30e-2)" "unprognostic (3.39e-2)" "potential prognostic unfavorable (4.41e-4)" "unprognostic (6.02e-2)" "unprognostic (7.26e-2)" "unprognostic (3.93e-2)" "potential prognostic unfavorable (2.05e-4)" "unprognostic (6.05e-2)" "unprognostic (1.20e-1)" "unprognostic (2.43e-1)" "unprognostic (3.09e-1)" "unprognostic (2.36e-1)" "unprognostic (3.31e-2)" "potential prognostic favorable (6.06e-5)" "unprognostic (1.34e-2)" "unprognostic (1.19e-2)" "unprognostic (3.06e-1)" "unprognostic (2.34e-2)" "unprognostic (4.19e-1)" "unprognostic (7.64e-2)" "unprognostic (1.07e-1)" "unprognostic (3.44e-2)" "unprognostic (1.71e-2)" "potential prognostic favorable (3.36e-4)" "unprognostic (2.76e-2)" "unprognostic (3.03e-2)" "unprognostic (2.84e-2)" "unprognostic (5.32e-2)" "unprognostic (2.24e-1)" LOXL4 "FLJ21889, LOXC" ENSG00000138131 "Lysyl oxidase like 4" Q96JB6 10 98247690-98268194 "Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial secretory cells: 28.8;Hepatic stellate cells: 32.3;Medullary thymic epithelial cells: 24.0;Pancreatic islet cells: 67.8;Renal collecting duct principal cells: 29.9;Respiratory basal cells: 29.3;Salivary basal cells: 60.9;Salivary myoepithelial cells: 25.2;Sertoli cells: 23.5;Submucosal glandular cells: 28.8;Thymic myoid cells: 59.8" "Cell type enriched" "Detected in some" 4 "fibroblast: 39.9" "Cancer enriched" "Detected in many" 5 "Skin Cutaneous Melanoma (TCGA): 76.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "skin cancer: 160.0" "Adrenal gland - Fibroblasts, Breast - Breast glandular cells (progenitors), Spleen - Fibroblasts_1, Stomach - Fibroblasts, Testis - Sertoli cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB033876, HPA037609" Approved Approved Vesicles "Secreted to extracellular matrix" Enzyme NA NA 5400000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 69: Skin cancer - ECM organization" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 72 Vesicles "CAB033876: , HPA037609: " "unprognostic (4.37e-3)" "unprognostic (4.93e-2)" "unprognostic (1.25e-2)" "unprognostic (3.18e-2)" "unprognostic (5.63e-3)" "validated prognostic unfavorable (3.40e-4)" "validated prognostic unfavorable (5.63e-4)" "unprognostic (4.70e-2)" "unprognostic (1.05e-3)" "unprognostic (4.61e-2)" "unprognostic (1.74e-3)" "unprognostic (3.97e-2)" "unprognostic (2.73e-2)" "unprognostic (9.75e-2)" "unprognostic (4.75e-2)" "unprognostic (4.51e-2)" "unprognostic (2.36e-1)" "unprognostic (9.74e-3)" "unprognostic (2.10e-3)" "unprognostic (5.45e-2)" "unprognostic (1.84e-1)" "unprognostic (9.19e-3)" "unprognostic (7.92e-2)" "unprognostic (1.72e-2)" "unprognostic (8.27e-2)" "unprognostic (4.55e-3)" "unprognostic (1.07e-1)" "unprognostic (2.10e-2)" "unprognostic (1.66e-1)" LPA "LP, Lp(a)" ENSG00000198670 Lipoprotein(a) P08519 6 160531482-160664275 "Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Lipid transport, Transport" "Hydrolase, Protease, Serine protease" Atherosclerosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 65 "liver: 71.8" "Cell type enhanced" "Detected in some" "Early primary spermatocytes: 15.1;Epididymal basal cells: 15.8;Hepatocytes: 82.0;Medullary thymic epithelial cells: 26.4;Ocular epithelial cells: 41.5;Prostatic hillock cells: 18.7;Proximal tubule cells: 18.7;Tuft cells: 11.5" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in single" 15 "Liver Hepatocellular Carcinoma (TCGA): 4.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "CAB016072, HPA060604" Supported "Secreted to blood" Transport NA NA 78800000000 12000000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 59: Leukemia - T-cell receptor" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 7 "CAB016072: , HPA060604: " "validated prognostic favorable (9.53e-4)" "validated prognostic favorable (2.76e-4)" "unprognostic (4.85e-2)" LPAR1 "edg-2, EDG2, Gpcr26, LPA1, Mrec1.3, rec.1.3, vzg-1" ENSG00000198121 "Lysophosphatidic acid receptor 1" Q92633 9 110873263-111038470 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 220.4" "Cell type enhanced" "Detected in many" "Fibro-adipogenic progenitors: 447.7;Fibroblasts: 347.3;Leydig cells: 190.4;Microglia: 360.3;Oligodendrocytes: 855.9;Peritubular myoid cells: 219.7;Pituicytes/FSCs: 254.7;Respiratory ionocytes: 213.4;Schwann cells: 412.1" "Group enriched" "Detected in many" 9 "central nervous system macrophage: 436.2;committed oligodendrocyte precursor: 330.0;fibroblast: 336.6;oligodendrocyte: 1006.4" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 34.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 8.7;eosinophil: 18.4" "Group enriched" "Detected in many" 6 "granulocytes: 18.4;monocytes: 8.7" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 68.7" "Adrenal gland - Fibroblasts, Breast - Fibroblasts, Colon - Enteric glia cells, Heart muscle - Fibroblasts, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 57 "unprognostic (1.77e-1)" "unprognostic (7.12e-2)" "unprognostic (8.80e-2)" "unprognostic (1.11e-1)" "unprognostic (9.95e-2)" "unprognostic (3.85e-1)" "unprognostic (3.26e-1)" "potential prognostic unfavorable (8.36e-4)" "unprognostic (1.50e-1)" "unprognostic (1.91e-2)" "unprognostic (1.10e-1)" "unprognostic (1.50e-1)" "unprognostic (1.07e-2)" "unprognostic (9.14e-3)" "unprognostic (6.33e-2)" "unprognostic (4.98e-2)" "unprognostic (3.21e-1)" "unprognostic (1.99e-1)" "unprognostic (1.15e-2)" "unprognostic (3.60e-3)" "unprognostic (2.08e-1)" "unprognostic (1.22e-1)" "unprognostic (1.44e-2)" "unprognostic (1.47e-1)" "unprognostic (1.47e-1)" "unprognostic (1.92e-3)" "unprognostic (2.46e-2)" "unprognostic (1.36e-1)" "unprognostic (2.12e-2)" "unprognostic (1.68e-3)" LPAR2 "EDG-4, EDG4, LPA2" ENSG00000064547 "Lysophosphatidic acid receptor 2" Q9HBW0 19 19623655-19628930 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 74.0" "Cell type enriched" "Detected in many" 4 "Neutrophils: 158.7" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 16.3;leukocyte: 15.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - T-cells, Minor Salivary Gland - Minor salivary glandular cells, Skin - Outer root sheath cells, Spleen - Neutrophils_2, Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA019616 Approved NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 84 "HPA019616: " "unprognostic (9.37e-2)" "unprognostic (2.06e-1)" "unprognostic (9.72e-2)" "unprognostic (3.16e-2)" "unprognostic (1.80e-2)" "unprognostic (2.51e-1)" "unprognostic (5.68e-2)" "unprognostic (8.60e-2)" "unprognostic (1.30e-3)" "unprognostic (5.83e-2)" "potential prognostic unfavorable (2.66e-7)" "unprognostic (6.19e-3)" "unprognostic (9.09e-2)" "unprognostic (9.76e-3)" "unprognostic (3.09e-1)" "unprognostic (1.24e-2)" "unprognostic (2.67e-2)" "unprognostic (1.57e-1)" "unprognostic (1.11e-2)" "unprognostic (3.60e-3)" "unprognostic (2.11e-2)" "unprognostic (1.76e-1)" "unprognostic (2.00e-1)" "unprognostic (1.24e-1)" "unprognostic (6.12e-2)" "unprognostic (2.51e-1)" "unprognostic (5.49e-2)" "potential prognostic favorable (1.75e-4)" "unprognostic (3.24e-1)" "unprognostic (1.75e-1)" "unprognostic (2.47e-1)" LPAR3 "Edg-7, EDG7, HOFNH30, LP-A3, LPA3, RP4-678I3" ENSG00000171517 "Lysophosphatidic acid receptor 3" Q9UBY5 1 84811602-84893206 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 34.2" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 49.6;Endometrial luminal cells: 124.8;Ependymal cells: 59.5;Fallopian secretory cells: 36.4;Fallopian tube ciliated cells: 106.4;Pancreatic acinar cells: 36.8;Prostatic glandular cells: 84.4;Prostatic hillock cells: 49.3;Respiratory ciliated cells: 74.3;Sertoli cells: 122.0" "Cell type enriched" "Detected in some" 5 "ependymal cell: 59.7" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 30.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 21.4" "Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA013421 Supported "Plasma membrane,Primary cilium" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 53: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 46 "Plasma membrane" "Primary cilium" "HPA013421: " "potential prognostic unfavorable (9.11e-4)" "unprognostic (4.44e-2)" "unprognostic (6.10e-3)" "unprognostic (1.80e-1)" "unprognostic (2.35e-2)" "unprognostic (5.63e-3)" "unprognostic (2.94e-3)" "unprognostic (1.73e-1)" "unprognostic (2.23e-1)" "unprognostic (3.15e-1)" "potential prognostic favorable (4.89e-4)" "unprognostic (2.48e-2)" "unprognostic (1.28e-3)" "unprognostic (7.69e-2)" "unprognostic (6.67e-2)" "unprognostic (1.12e-1)" "unprognostic (2.23e-2)" "unprognostic (3.76e-2)" LPAR4 "GPR23, LPA4, P2RY9, P2Y5-LIKE, P2Y9" ENSG00000147145 "Lysophosphatidic acid receptor 4" Q99677 X 78747709-78758714 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "ovary: 3.1" "Cell type enhanced" "Detected in some" "Astrocytes: 19.6;Bergmann glia: 19.3;Ependymal cells: 34.8;Fibro-adipogenic progenitors: 7.3;Leydig cells: 44.7;Megakaryocytes: 6.2;Oligodendrocyte progenitor cells: 9.9;Ovarian stromal cells: 6.2;Peritubular myoid cells: 6.5;Thymocytes: 7.6" "Cell type enhanced" "Detected in some" "astrocyte: 22.6;Bergmann glia: 20.2;ependymal cell: 38.6" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 2.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "basophil: 7.8" "Lineage enriched" "Detected in many" 7 "granulocytes: 7.8" "Cancer enhanced" "Detected in some" "Bone cancer: 2.0;testis cancer: 2.5" "Kidney - Fibroblasts, Lung - Fibroblasts_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA046563, HPA054951, HPA055571" Uncertain Supported "Nuclear bodies,Vesicles,Plasma membrane" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 75: Ovary - Mixed function" "Cluster 55: Non-specific - Transcription" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 94: Gonadal somatic cells - Mixed function" "Plasma membrane" "Nuclear bodies, Vesicles" "HPA046563: , HPA054951: , HPA055571: " "unprognostic (6.05e-2)" "unprognostic (1.11e-1)" "unprognostic (4.56e-3)" "unprognostic (1.36e-1)" LPAR5 "GPR92, GPR93, KPG_010, LPA5" ENSG00000184574 "Lysophosphatidic acid receptor 5" Q9H1C0 12 6618835-6635960 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 20.8" "Cell type enhanced" "Detected in many" "B-cells: 25.7;Esophageal apical cells: 89.6;Esophageal suprabasal cells: 64.1;Hofbauer cells: 81.8;Kupffer cells: 46.1;Microglia: 119.7;Platelets: 55.1" "Cell type enriched" "Detected in some" 9 "central nervous system macrophage: 137.1" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 32.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 4 "B-cells: 84.1;T-cells: 66.9" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adipose visceral - Mesothelial cells, Adrenal gland - Macrophages, Heart muscle - Cardiomyocytes, Liver - Kupffer cells, Skeletal muscle - Macrophages, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA013170 Approved NA NA "Cluster 24: Non-specific - Transcription" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" "HPA013170: " "unprognostic (9.55e-2)" "unprognostic (1.96e-1)" "unprognostic (1.83e-1)" "unprognostic (7.59e-2)" "unprognostic (6.50e-2)" "unprognostic (8.03e-2)" "unprognostic (2.95e-1)" "unprognostic (3.61e-2)" "unprognostic (2.86e-1)" "unprognostic (4.92e-1)" "unprognostic (3.18e-1)" "unprognostic (2.01e-1)" "unprognostic (7.29e-3)" "unprognostic (6.03e-2)" "unprognostic (4.98e-3)" "unprognostic (3.99e-3)" "unprognostic (4.21e-1)" "unprognostic (7.45e-2)" "unprognostic (1.30e-2)" "unprognostic (4.18e-2)" "unprognostic (3.84e-3)" "unprognostic (1.01e-3)" "unprognostic (1.02e-1)" "unprognostic (2.63e-1)" "unprognostic (2.83e-1)" "unprognostic (1.62e-2)" "unprognostic (2.53e-1)" "potential prognostic favorable (5.48e-4)" "unprognostic (9.63e-2)" LPAR6 "P2RY5, P2Y5" ENSG00000139679 "Lysophosphatidic acid receptor 6" P43657 13 48389567-48444704 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "cDC: 313.3;Early spermatids: 442.5;Epicardial cells: 343.4;Esophageal apical cells: 319.1;Late spermatids: 412.9;Macrophages: 227.8;Microglia: 893.3" "Cell type enriched" "Detected in all" 5 "central nervous system macrophage: 1088.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Breast - T-cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028934, HPA076273" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 6: Leukemia - Signal transduction" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 9 "Plasma membrane" Vesicles "HPA028934: , HPA076273: " "unprognostic (1.76e-1)" "unprognostic (1.28e-1)" "unprognostic (1.31e-2)" "unprognostic (4.68e-2)" "unprognostic (1.84e-1)" "unprognostic (7.77e-2)" "unprognostic (4.04e-2)" "unprognostic (1.78e-1)" "unprognostic (2.33e-2)" "unprognostic (4.72e-1)" "unprognostic (1.64e-1)" "unprognostic (2.21e-2)" "unprognostic (9.35e-2)" "unprognostic (1.36e-2)" "unprognostic (4.95e-3)" "potential prognostic favorable (2.44e-5)" "unprognostic (1.68e-2)" "unprognostic (1.35e-1)" "unprognostic (1.08e-1)" "unprognostic (8.39e-3)" "unprognostic (1.17e-1)" "unprognostic (1.15e-1)" "unprognostic (2.04e-1)" "unprognostic (1.58e-1)" "unprognostic (2.83e-1)" "unprognostic (2.39e-1)" "unprognostic (1.76e-2)" "unprognostic (1.09e-2)" "unprognostic (1.17e-1)" "unprognostic (1.65e-2)" "unprognostic (2.10e-1)" LPCAT1 "AGPAT10, AGPAT9, AYTL2, FLJ12443, LPLAT8" ENSG00000153395 "Lysophosphatidylcholine acyltransferase 1" Q8NF37 5 1456480-1523962 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 53.5;lymphoid tissue: 35.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 66.2;Alveolar cells type 2: 67.7;Cone photoreceptor cells: 39.3;monocytes: 37.5;Neutrophils: 93.3;NK-cells: 59.4;Rod photoreceptor cells: 62.2;Transitional alveolar cells: 40.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 35.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012501, HPA022268" Enhanced Supported "Endoplasmic reticulum,Lipid droplets" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 5: Spleen - Immune response" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 14 "Endoplasmic reticulum" "Lipid droplets" "HPA012501: , HPA022268: " "unprognostic (3.74e-2)" "unprognostic (7.04e-3)" "unprognostic (4.61e-3)" "unprognostic (3.71e-2)" "unprognostic (2.25e-1)" "unprognostic (2.80e-2)" "unprognostic (5.27e-2)" "unprognostic (1.21e-2)" "unprognostic (2.33e-1)" "unprognostic (6.72e-3)" "unprognostic (3.47e-1)" "unprognostic (2.30e-1)" "validated prognostic unfavorable (1.78e-4)" "validated prognostic unfavorable (5.47e-6)" "unprognostic (1.46e-2)" "unprognostic (4.46e-2)" "potential prognostic unfavorable (2.39e-4)" "unprognostic (2.75e-1)" "unprognostic (7.62e-2)" "unprognostic (2.32e-2)" "unprognostic (1.10e-1)" "unprognostic (5.37e-2)" "unprognostic (5.46e-2)" "unprognostic (5.04e-2)" "unprognostic (1.23e-2)" "unprognostic (1.40e-1)" "unprognostic (1.35e-1)" "unprognostic (7.61e-2)" "unprognostic (2.23e-3)" LPCAT2 "AGPAT11, AYTL1, FLJ20481, LPLAT9, LysoPAFAT" ENSG00000087253 "Lysophosphatidylcholine acyltransferase 2" Q7L5N7 16 55509072-55586666 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 83.4;thyroid gland: 80.8" "Cell type enhanced" "Detected in many" "Hematopoietic stem cells: 193.6;Kupffer cells: 180.4;Mast cells: 248.5;Microglia: 730.5;Neutrophil progenitors: 539.1;Neutrophils: 499.4" "Cell type enriched" "Detected in many" 7 "central nervous system macrophage: 962.4" "Cancer enhanced" "Detected in all" "Thyroid Carcinoma (TCGA): 50.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 151.7;eosinophil: 199.7" "Lineage enriched" "Detected in many" 5 "granulocytes: 199.7" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Adrenal gland - Adrenal cortex cells, Skeletal muscle - Endothelial cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007891, HPA008433" Enhanced Supported Supported "Endoplasmic reticulum,Lipid droplets" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 26 "Endoplasmic reticulum" "Lipid droplets" "HPA007891: , HPA008433: " "unprognostic (1.71e-1)" "unprognostic (2.14e-1)" "unprognostic (9.36e-2)" "unprognostic (3.91e-2)" "unprognostic (7.61e-2)" "unprognostic (4.52e-2)" "unprognostic (2.67e-1)" "unprognostic (2.08e-1)" "unprognostic (1.12e-3)" "unprognostic (1.95e-1)" "unprognostic (7.71e-3)" "unprognostic (2.17e-1)" "unprognostic (1.34e-1)" "validated prognostic unfavorable (3.54e-4)" "validated prognostic unfavorable (6.64e-4)" "unprognostic (2.57e-2)" "unprognostic (3.41e-2)" "unprognostic (4.32e-1)" "unprognostic (8.59e-2)" "unprognostic (4.17e-2)" "unprognostic (6.17e-2)" "unprognostic (2.51e-3)" "unprognostic (8.73e-2)" "unprognostic (1.19e-1)" "unprognostic (2.29e-1)" "unprognostic (1.03e-1)" "unprognostic (2.35e-1)" "unprognostic (5.81e-3)" "unprognostic (4.22e-2)" "unprognostic (3.26e-1)" "unprognostic (7.77e-2)" LPCAT3 "C3F, LPLAT12, MBOAT5, nessy, OACT5" ENSG00000111684 "Lysophosphatidylcholine acyltransferase 3" Q6P1A2 12 6976185-7018477 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 255.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Kidney - Macrophages, Liver - Hepatocytes, Lung - Alveolar cells type 2, Prostate - Prostate basal glandular cells, Skin - Inner root sheath cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 25: Non-specific - Transcription" "Cluster 18: Liver cancer - Metabolism" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 8 "unprognostic (1.61e-2)" "unprognostic (1.42e-1)" "unprognostic (1.92e-1)" "unprognostic (2.17e-1)" "unprognostic (9.84e-2)" "unprognostic (2.39e-1)" "unprognostic (1.98e-1)" "unprognostic (1.06e-1)" "unprognostic (2.59e-1)" "unprognostic (3.67e-1)" "potential prognostic favorable (4.14e-4)" "unprognostic (3.83e-1)" "potential prognostic favorable (2.04e-4)" "unprognostic (1.01e-2)" "potential prognostic unfavorable (2.84e-4)" "unprognostic (7.29e-2)" "unprognostic (2.00e-1)" "unprognostic (2.16e-1)" "unprognostic (2.48e-1)" "unprognostic (3.56e-2)" "unprognostic (7.95e-2)" "unprognostic (3.72e-1)" "unprognostic (5.67e-2)" "unprognostic (4.53e-2)" "unprognostic (2.00e-2)" "unprognostic (3.55e-1)" "unprognostic (6.66e-2)" "unprognostic (2.94e-1)" "unprognostic (2.75e-1)" "unprognostic (2.85e-2)" "unprognostic (5.89e-1)" LPCAT4 "AGPAT7, AYTL3, FLJ10257, LPAAT-eta, LPEAT2, LPLAT10" ENSG00000176454 "Lysophosphatidylcholine acyltransferase 4" Q643R3 15 34358633-34367196 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 60.2" "Cell type enhanced" "Detected in many" "Colonocytes: 90.0;Esophageal apical cells: 206.9;Foveolar cells: 240.6;Prostatic hillock cells: 112.8;Retinal ganglion cells: 77.3;Urothelial cells: 113.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Skeletal muscle - Fibroblasts, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057321 Supported NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 64: Non-specific - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 68: Foveolar cells - Mucosal defense" "HPA057321: " "unprognostic (5.34e-2)" "unprognostic (2.03e-2)" "unprognostic (7.45e-2)" "unprognostic (2.26e-1)" "unprognostic (1.78e-1)" "unprognostic (2.89e-2)" "unprognostic (8.80e-3)" "potential prognostic favorable (3.00e-5)" "unprognostic (2.24e-3)" "unprognostic (1.27e-1)" "unprognostic (1.44e-1)" "unprognostic (1.59e-2)" "unprognostic (8.43e-2)" "potential prognostic unfavorable (3.46e-5)" "unprognostic (8.14e-2)" "unprognostic (1.11e-2)" "unprognostic (5.82e-2)" "unprognostic (1.28e-1)" "unprognostic (1.73e-1)" "unprognostic (3.97e-2)" "unprognostic (1.13e-2)" "unprognostic (3.27e-3)" "unprognostic (1.10e-1)" "unprognostic (5.08e-1)" "unprognostic (1.11e-1)" "unprognostic (6.78e-2)" "unprognostic (1.08e-2)" "unprognostic (2.12e-2)" "unprognostic (1.71e-1)" "unprognostic (9.70e-2)" "unprognostic (2.58e-3)" LPGAT1 "FAM34A, FAM34A1, KIAA0205, LPLAT7, NET8" ENSG00000123684 "Lysophosphatidylglycerol acyltransferase 1" Q92604 1 211743457-211830763 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Choroid plexus epithelial cells: 529.6;Early spermatids: 640.1;Neutrophil progenitors: 706.6;Neutrophils: 900.3;Oligodendrocytes: 662.6" "Cell type enhanced" "Detected in all" "oligodendrocyte: 826.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 16.2" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 42: Retina - Visual perception" "Cluster 11: White matter - Signal transduction" "Cluster 1: Neuronal - Visual perception" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 18 "unprognostic (4.76e-2)" "unprognostic (8.37e-3)" "unprognostic (3.12e-2)" "unprognostic (2.11e-2)" "unprognostic (1.39e-1)" "unprognostic (8.92e-2)" "unprognostic (1.83e-1)" "unprognostic (8.42e-2)" "unprognostic (5.44e-2)" "unprognostic (3.98e-3)" "unprognostic (4.90e-3)" "unprognostic (2.41e-2)" "potential prognostic unfavorable (7.03e-4)" "unprognostic (4.89e-3)" "unprognostic (3.38e-1)" "unprognostic (1.78e-3)" "unprognostic (8.42e-2)" "unprognostic (2.72e-1)" "unprognostic (9.07e-2)" "unprognostic (1.31e-1)" "unprognostic (4.87e-3)" "unprognostic (3.33e-1)" "unprognostic (2.10e-1)" "unprognostic (2.67e-1)" "unprognostic (5.26e-2)" "unprognostic (1.09e-2)" "unprognostic (1.33e-1)" "unprognostic (6.13e-2)" "unprognostic (1.60e-1)" "unprognostic (2.19e-2)" "unprognostic (1.92e-2)" LPIN1 KIAA0188 ENSG00000134324 "Lipin 1" Q14693 2 11677595-11827409 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Transcription, Transcription regulation" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 180.0;tongue: 128.3" "Group enriched" "Detected in many" 4 "Esophageal apical cells: 1073.1;Late spermatids: 3297.6" "Cell type enhanced" "Detected in all" "astrocyte: 450.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Pituitary gland - Somatotropes, Prostate - Smooth muscle cells, Spleen - B-cells (Spleen), Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024591, HPA038021" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 19: Astrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 20 Cytosol "Plasma membrane" "HPA024591: , HPA038021: " "unprognostic (2.56e-2)" "unprognostic (1.56e-1)" "unprognostic (2.12e-1)" "unprognostic (6.02e-2)" "unprognostic (2.75e-1)" "unprognostic (2.59e-1)" "unprognostic (1.87e-1)" "unprognostic (1.28e-2)" "unprognostic (6.18e-2)" "unprognostic (5.78e-2)" "unprognostic (1.35e-1)" "unprognostic (7.11e-3)" "unprognostic (8.69e-2)" "unprognostic (3.46e-2)" "unprognostic (2.76e-1)" "unprognostic (5.27e-2)" "unprognostic (2.56e-2)" "unprognostic (4.10e-1)" "unprognostic (5.99e-3)" "unprognostic (1.00e-2)" "unprognostic (1.06e-1)" "unprognostic (2.33e-2)" "unprognostic (2.78e-1)" "unprognostic (6.23e-3)" "unprognostic (2.51e-2)" "unprognostic (2.13e-1)" "unprognostic (2.29e-1)" "unprognostic (4.82e-2)" "unprognostic (4.21e-1)" "unprognostic (3.92e-3)" "unprognostic (4.94e-2)" LPIN2 KIAA0249 ENSG00000101577 "Lipin 2" Q92539 18 2885296-3013144 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Transcription, Transcription regulation" Hydrolase "Congenital dyserythropoietic anemia, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 141.2" "Cell type enhanced" "Detected in all" "Foveolar cells: 385.3;Microglia: 333.7" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 422.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 6 "granulocytes: 32.0;NK-cells: 13.3;T-cells: 12.0" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015223, HPA017857, HPA030550" Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" Yes No "Cluster 35: Neutrophils - Protein binding" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 49: Hindbrain - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 24: Neutrophils - Innate immunity signal integration" 4 Cytosol "Plasma membrane, Actin filaments" "CAB015223: , HPA017857: , HPA030550: " "unprognostic (1.94e-1)" "unprognostic (1.52e-1)" "unprognostic (8.36e-2)" "unprognostic (2.09e-1)" "unprognostic (6.32e-2)" "unprognostic (1.16e-3)" "unprognostic (2.91e-1)" "unprognostic (8.27e-3)" "potential prognostic favorable (5.62e-4)" "unprognostic (1.33e-2)" "potential prognostic favorable (6.85e-5)" "unprognostic (2.74e-3)" "unprognostic (1.47e-1)" "unprognostic (2.24e-3)" "unprognostic (1.33e-1)" "unprognostic (4.75e-2)" "unprognostic (2.39e-2)" "unprognostic (9.05e-3)" "unprognostic (2.43e-1)" "unprognostic (3.16e-3)" "unprognostic (3.81e-3)" "unprognostic (4.10e-1)" "unprognostic (1.22e-1)" "unprognostic (2.11e-1)" "unprognostic (4.78e-2)" "unprognostic (2.77e-1)" "unprognostic (9.61e-3)" "unprognostic (1.99e-1)" "unprognostic (4.86e-1)" "unprognostic (1.30e-1)" "unprognostic (6.73e-3)" LPIN3 "LIPN3L, SMP2" ENSG00000132793 "Lipin 3" Q9BQK8 20 41340821-41360582 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Enterocytes: 88.2;Esophageal apical cells: 72.7;Late spermatids: 291.3;Proximal tubule cells: 86.9" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 22.6;fibroblast: 26.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 2.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Kidney - Macrophages" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA051466, HPA052667, HPA070640" Approved Supported Cytosol NA NA "Cluster 77: Intestine - Digestion" "Cluster 8: Immune cells - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 5 Cytosol "HPA051466: , HPA052667: , HPA070640: " "unprognostic (1.98e-2)" "unprognostic (6.61e-2)" "unprognostic (5.64e-2)" "unprognostic (3.55e-3)" "unprognostic (3.03e-1)" "unprognostic (2.75e-1)" "unprognostic (2.31e-2)" "unprognostic (6.52e-2)" "unprognostic (2.00e-2)" "unprognostic (1.25e-1)" "unprognostic (1.70e-3)" "unprognostic (4.68e-2)" "unprognostic (4.30e-3)" "unprognostic (5.96e-3)" "unprognostic (1.16e-1)" "unprognostic (2.52e-1)" "unprognostic (3.39e-2)" "unprognostic (9.07e-2)" "unprognostic (3.63e-2)" "potential prognostic unfavorable (7.22e-5)" "unprognostic (1.40e-1)" "unprognostic (3.08e-1)" "unprognostic (6.02e-3)" "unprognostic (1.67e-1)" "potential prognostic favorable (9.09e-4)" "unprognostic (6.45e-3)" "unprognostic (7.66e-3)" "unprognostic (3.70e-2)" "unprognostic (3.04e-1)" "unprognostic (1.06e-1)" "unprognostic (1.77e-1)" LPL LIPD ENSG00000175445 "Lipoprotein lipase" P06858 8 19901717-19967259 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" "Heparin-binding, Hydrolase" "Disease variant, FDA approved drug targets, Hyperlipidemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 880.1;heart muscle: 327.9" "Group enriched" "Detected in many" 4 "Adipocytes: 887.8;Breast lactating cells: 1529.1;Schwann cells: 410.2" "Group enriched" "Detected in many" 9 "cerebellar inhibitory: 150.9;medium spiny neuron: 166.6;pericyte: 236.7" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 62.0" "Region enhanced" "Detected in all" "basal ganglia: 106.9" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 4.2" "Lineage enriched" "Detected in single" 6 "monocytes: 4.2" "Cancer enhanced" "Detected in many" "cervical cancer: 15.6" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Minor Salivary Gland - Adipocytes (Minor salivary gland), Skin - Adipocytes (Skin), Testis - Endothelial cells" "Region enhanced" "Detected in many" "basal ganglia: 45.3" "Group enriched" "Detected in all" 4 "basal ganglia: 101.9;spinal cord: 74.2" HPA048749 Approved Vesicles "Secreted to blood" Enzyme NA NA 32000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 89: Adipocytes - Lipid metabolism" 13 Vesicles "HPA048749: " "unprognostic (1.40e-1)" "unprognostic (1.38e-1)" "unprognostic (7.05e-3)" "unprognostic (9.02e-2)" "unprognostic (1.93e-1)" "unprognostic (1.07e-1)" "unprognostic (1.71e-1)" "unprognostic (9.05e-2)" "unprognostic (1.61e-2)" "unprognostic (1.88e-2)" "validated prognostic favorable (2.81e-6)" "validated prognostic favorable (5.95e-5)" "unprognostic (2.19e-2)" "unprognostic (3.01e-2)" "unprognostic (1.00e-1)" "unprognostic (3.23e-3)" "unprognostic (7.53e-2)" "unprognostic (6.01e-3)" "unprognostic (1.90e-2)" "unprognostic (4.40e-2)" "unprognostic (1.78e-2)" "unprognostic (8.05e-3)" "unprognostic (1.75e-1)" "unprognostic (1.62e-1)" "unprognostic (2.97e-1)" "unprognostic (4.34e-1)" "unprognostic (4.89e-2)" "potential prognostic unfavorable (1.21e-4)" "unprognostic (3.55e-3)" "unprognostic (2.43e-1)" LPO SPO ENSG00000167419 Lactoperoxidase P22079 17 58218548-58268518 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrogen peroxide" "Antimicrobial, Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 841 "salivary gland: 967.3" "Cell type enhanced" "Detected in some" "Breast lactating cells: 289.2;Lacrimal acinar cells: 184.8;Salivary acinar cells: 1162.3;Salivary myoepithelial cells: 330.1;Submucosal glandular cells: 66.0" "Cell type enhanced" "Detected in some" "midbrain-derived inhibitory: 21.8" "Not detected" "Not detected" "Region enhanced" "Detected in some" "midbrain: 5.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Leukemia: 1.4" "Minor Salivary Gland - Minor salivary glandular cells, Skin - Sebaceous gland cells, Spleen - Neutrophils_1, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA028688 Enhanced Supported "Secreted to digestive system" Enzyme NA NA "Cluster 82: Salivary gland - Secretion" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 1 "HPA028688: " "unprognostic (5.99e-2)" LPP ENSG00000145012 "LIM domain containing preferred translocation partner in lipoma" Q93052 3 188153284-188890671 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" Activator "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 128.4" "Cell type enhanced" "Detected in many" "Late spermatids: 2886.1;Salivary myoepithelial cells: 2477.7;Smooth muscle cells: 3744.0;Vascular smooth muscle cells: 2741.1" "Cell type enhanced" "Detected in all" "vascular associated smooth muscle cell: 2556.0" "Cancer enhanced" "Detected in all" "Stomach Adenocarcinoma (TCGA): 77.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 18.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Skin - Endothelial cells, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA011133, HPA017342" Enhanced Supported "Plasma membrane,Cell Junctions,Focal adhesion sites,Cytosol" NA NA 230000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 12: Non-specific - Vasculature" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 62: Smooth muscle cells - Muscle contraction" 10 "Focal adhesion sites, Cytosol" "Plasma membrane, Cell Junctions" "HPA011133: , HPA017342: " "unprognostic (9.67e-3)" "unprognostic (2.34e-1)" "unprognostic (2.19e-1)" "potential prognostic unfavorable (1.26e-4)" "unprognostic (3.77e-1)" "unprognostic (1.12e-2)" "unprognostic (2.13e-1)" "unprognostic (1.37e-1)" "unprognostic (1.97e-1)" "unprognostic (7.63e-3)" "potential prognostic favorable (3.76e-6)" "unprognostic (1.15e-2)" "unprognostic (2.20e-1)" "unprognostic (5.24e-3)" "unprognostic (2.86e-1)" "unprognostic (6.97e-2)" "potential prognostic unfavorable (9.24e-4)" "unprognostic (1.06e-1)" "unprognostic (5.37e-2)" "unprognostic (8.35e-2)" "potential prognostic unfavorable (1.34e-4)" "unprognostic (1.08e-2)" "unprognostic (2.37e-1)" "unprognostic (8.60e-2)" "unprognostic (6.72e-2)" "unprognostic (1.91e-2)" "unprognostic (1.68e-1)" "unprognostic (3.22e-2)" "unprognostic (5.49e-2)" "unprognostic (1.01e-3)" "unprognostic (1.13e-1)" LPXN LDPL ENSG00000110031 Leupaxin O60711 11 58526871-58578220 "Predicted intracellular proteins" "Cell adhesion, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 111.0" "Cell type enhanced" "Detected in many" "cDC: 190.7;Innate lymphoid cells: 348.1;Macrophages: 191.6;Mast cells: 181.6;monocytes: 366.5;pDCs: 296.2;Plasma cells: 184.0;T-cells: 165.9" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 167.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "lymphoma: 180.9" "Breast - T-cells, Spleen - B-cells (Spleen), Stomach - T-cells, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043741, CAB046478, HPA061441" Enhanced Supported "Nuclear speckles,Focal adhesion sites,Cytosol" No No "Cluster 13: Non-specific - Mitochondria" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 20 "Focal adhesion sites" "Nuclear speckles, Cytosol" "CAB046478: , HPA043741: , HPA061441: " "unprognostic (5.26e-3)" "unprognostic (4.26e-3)" "unprognostic (5.51e-2)" "unprognostic (1.84e-1)" "unprognostic (2.70e-1)" "unprognostic (1.01e-1)" "unprognostic (1.99e-1)" "unprognostic (1.91e-2)" "unprognostic (7.51e-3)" "unprognostic (9.15e-2)" "unprognostic (1.64e-1)" "unprognostic (1.83e-1)" "unprognostic (9.01e-3)" "unprognostic (9.56e-3)" "unprognostic (1.03e-2)" "potential prognostic favorable (3.74e-4)" "unprognostic (3.52e-2)" "unprognostic (1.07e-1)" "unprognostic (2.58e-1)" "unprognostic (1.77e-1)" "unprognostic (5.49e-2)" "unprognostic (3.06e-2)" "unprognostic (2.25e-2)" "unprognostic (1.71e-1)" "unprognostic (2.12e-1)" "unprognostic (1.79e-2)" "unprognostic (6.47e-2)" "unprognostic (9.75e-2)" "unprognostic (4.63e-2)" "unprognostic (1.05e-1)" "unprognostic (3.85e-2)" LRAT LCA14 ENSG00000121207 "Lecithin retinol acyltransferase" O95237 4 154626945-154753120 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sensory transduction, Vision" "Acyltransferase, Transferase" "Disease variant, Leber congenital amaurosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.9;liver: 2.0" "Cell type enriched" "Detected in many" 12 "Retinal pigment epithelial cells: 1956.7" "Group enriched" "Detected in many" 5 "astrocyte: 62.5;choroid plexus epithelial cell: 85.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.9" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Colon - Enteric glia cells, Lung - Alveolar cells type 2, Skin - Hair cortex cells, Skin - Outer root sheath cells, Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA070726 Approved "Endoplasmic reticulum,Golgi apparatus,Plasma membrane,Basal body" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 39: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" 3 "Endoplasmic reticulum, Golgi apparatus" "Plasma membrane, Basal body" "HPA070726: " "unprognostic (2.23e-1)" "unprognostic (1.87e-1)" "unprognostic (4.95e-2)" "unprognostic (2.04e-1)" "unprognostic (2.46e-1)" "unprognostic (3.32e-2)" "unprognostic (2.60e-2)" "unprognostic (6.11e-2)" LRATD1 "FAM84A, FLJ35392, NSE1" ENSG00000162981 "LRAT domain containing 1" Q96KN4 2 14632700-14650814 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 30.4;intestine: 38.4" "Cell type enhanced" "Detected in many" "Colonocytes: 171.1;Cytotrophoblasts: 198.5;Enteric stem cells: 203.7;Enteric transient amplifying cells: 158.1;Epididymal principal cells: 187.8;Esophageal apical cells: 184.9;Esophageal suprabasal cells: 163.4;Goblet cells: 118.8;Migrating cytotrophoblasts: 120.3;Prostatic glandular cells: 125.4;Syncytiotrophoblasts: 222.4;Urothelial cells: 220.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 52.2" "Adipose subcutaneous - Smooth muscle cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Prostate glandular cells, Skin - Outer root sheath cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047703 Uncertain Approved Nucleoplasm NA NA "Cluster 17: Intestine - Digestion" "Cluster 53: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 3 Nucleoplasm "HPA047703: " "unprognostic (6.67e-2)" "unprognostic (2.72e-2)" "unprognostic (5.28e-2)" "unprognostic (2.04e-2)" "potential prognostic favorable (9.29e-5)" "unprognostic (1.09e-1)" "unprognostic (1.40e-3)" "unprognostic (2.03e-1)" "unprognostic (7.97e-2)" "potential prognostic favorable (2.43e-5)" "unprognostic (2.70e-2)" "potential prognostic unfavorable (4.54e-4)" "unprognostic (2.10e-1)" "unprognostic (1.89e-1)" "unprognostic (3.11e-2)" "unprognostic (1.86e-2)" "unprognostic (7.52e-2)" "unprognostic (6.00e-2)" "unprognostic (1.22e-1)" "unprognostic (1.71e-1)" "unprognostic (5.57e-2)" "potential prognostic favorable (7.28e-5)" "unprognostic (1.07e-1)" "unprognostic (3.48e-2)" "unprognostic (6.14e-2)" "unprognostic (1.48e-1)" "unprognostic (9.93e-2)" "unprognostic (1.04e-1)" LRATD2 "BCMP101, FAM84B, NSE2" ENSG00000168672 "LRAT domain containing 2" Q96KN1 8 126552443-126558478 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 41.1" "Cell type enhanced" "Detected in many" "Breast lactating cells: 139.9;Endometrial glandular cells: 292.5;Endometrial luminal cells: 104.0;Esophageal apical cells: 104.7;Gastric chief cells: 84.1;Parietal cells: 99.0;Retinal pigment epithelial cells: 85.3" "Cell type enhanced" "Detected in many" "ependymal cell: 46.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate basal glandular cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050782, HPA062115" Approved Approved Nucleoplasm NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 60: Stomach - Digestion" "Cluster 46: Brainstem - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 51: Secretory epithelial cells - Mixed function" 16 Nucleoplasm "HPA050782: , HPA062115: " "potential prognostic favorable (1.82e-4)" "potential prognostic unfavorable (7.14e-5)" "unprognostic (6.85e-3)" "unprognostic (1.17e-1)" "potential prognostic unfavorable (7.76e-4)" "unprognostic (5.58e-2)" "unprognostic (4.34e-3)" "unprognostic (2.48e-1)" "unprognostic (6.36e-2)" "validated prognostic favorable (3.17e-8)" "validated prognostic favorable (8.35e-5)" "unprognostic (9.34e-2)" "unprognostic (2.55e-1)" "unprognostic (1.10e-2)" "potential prognostic unfavorable (3.95e-4)" "unprognostic (2.08e-1)" "unprognostic (5.53e-2)" "unprognostic (1.31e-2)" "unprognostic (6.54e-2)" "unprognostic (1.04e-3)" "unprognostic (1.88e-2)" "unprognostic (2.54e-3)" "unprognostic (3.74e-2)" "unprognostic (3.91e-1)" "unprognostic (1.61e-2)" "unprognostic (1.44e-2)" "unprognostic (2.26e-1)" "unprognostic (2.08e-1)" "unprognostic (2.60e-2)" LRBA "BGL, CDC4L, LAB300, LBA" ENSG00000198589 "LPS responsive beige-like anchor protein" P50851 4 150264435-151015727 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal convoluted tubule cells: 1526.5;Hematopoietic stem cells: 1843.4;Renal collecting duct principal cells: 1611.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Skin - Keratinocyte (other), Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019366, HPA023597" Approved Supported "Golgi apparatus,Cytosol" NA NA 180000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 51: Secretory epithelial cells - Mixed function" 7 "Golgi apparatus" Cytosol "HPA019366: , HPA023597: " "unprognostic (2.21e-1)" "unprognostic (6.31e-2)" "unprognostic (4.14e-1)" "unprognostic (3.54e-2)" "unprognostic (6.28e-3)" "unprognostic (7.56e-2)" "unprognostic (1.53e-1)" "unprognostic (1.71e-1)" "unprognostic (6.39e-2)" "unprognostic (4.12e-2)" "potential prognostic favorable (5.36e-10)" "unprognostic (2.83e-3)" "unprognostic (1.44e-2)" "unprognostic (1.59e-1)" "unprognostic (1.95e-1)" "unprognostic (2.93e-1)" "unprognostic (3.72e-2)" "unprognostic (6.70e-3)" "unprognostic (2.05e-1)" "unprognostic (6.18e-3)" "unprognostic (2.45e-1)" "unprognostic (3.35e-2)" "unprognostic (1.07e-1)" "unprognostic (6.00e-2)" "unprognostic (4.66e-3)" "unprognostic (1.55e-2)" "unprognostic (4.84e-2)" "unprognostic (2.76e-1)" "unprognostic (1.78e-1)" "unprognostic (1.46e-1)" "unprognostic (2.98e-2)" LRCH1 "CHDC1, KIAA1016" ENSG00000136141 "Leucine rich repeats and calponin homology domain containing 1" Q9Y2L9 13 46553168-46753040 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Bergmann glia: 507.7;Distal convoluted tubule cells: 743.6;Microglia: 583.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Skeletal muscle - Endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021536 Approved Approved "Nucleoli,Actin filaments,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 49: Non-specific - Transcription" "Cluster 35: Non-specific - DNA binding" "Cluster 19: Non-specific - Unknown function" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 22 "Actin filaments, Cytosol" Nucleoli "HPA021536: " "unprognostic (2.79e-2)" "unprognostic (1.08e-1)" "unprognostic (2.03e-1)" "unprognostic (1.08e-3)" "unprognostic (1.18e-1)" "unprognostic (9.35e-2)" "unprognostic (4.06e-2)" "unprognostic (3.20e-1)" "unprognostic (1.23e-1)" "unprognostic (1.54e-3)" "validated prognostic favorable (3.44e-6)" "validated prognostic favorable (1.97e-5)" "unprognostic (7.45e-3)" "unprognostic (5.87e-2)" "unprognostic (1.32e-1)" "unprognostic (2.43e-2)" "unprognostic (3.07e-3)" "unprognostic (3.20e-3)" "unprognostic (2.07e-1)" "unprognostic (6.10e-3)" "unprognostic (2.06e-3)" "unprognostic (3.42e-3)" "unprognostic (1.37e-1)" "unprognostic (1.48e-1)" "unprognostic (5.54e-1)" "unprognostic (2.01e-2)" "unprognostic (1.86e-1)" "unprognostic (2.19e-1)" "unprognostic (8.98e-2)" "unprognostic (1.19e-1)" "unprognostic (3.22e-1)" LRCH2 KIAA1495 ENSG00000130224 "Leucine rich repeats and calponin homology domain containing 2" Q5VUJ6 X 115110616-115234096 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bergmann glia: 45.8;Brain excitatory neurons: 43.6;Brain inhibitory neurons: 64.3;Corticotrophs: 70.0;Gonadotrophs: 64.6;Lactotrophs: 65.0;Lymphatic endothelial cells: 63.9;Oligodendrocyte progenitor cells: 69.8;Other brain neurons: 61.7;Pericytes: 43.8;Pituicytes/FSCs: 67.7;Retinal amacrine cells: 47.1;Somatotrophs: 44.9;Thyrotrophs: 52.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 8.3;testis cancer: 6.4" "Breast - Endothelial cells, Prostate - Smooth muscle cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003233, HPA076892" Approved Approved "Plasma membrane" NA NA "Cluster 65: Brain - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 110: Mural cells - ECM organization" 17 "Plasma membrane" "HPA003233: , HPA076892: " "unprognostic (1.63e-1)" "unprognostic (6.41e-3)" "unprognostic (9.37e-2)" "unprognostic (2.69e-2)" "potential prognostic favorable (7.81e-4)" "unprognostic (3.99e-2)" "unprognostic (2.72e-2)" "unprognostic (1.47e-2)" "unprognostic (1.48e-1)" "unprognostic (2.58e-1)" "unprognostic (9.36e-2)" "unprognostic (2.47e-1)" "unprognostic (9.51e-3)" "unprognostic (5.73e-2)" "unprognostic (1.34e-1)" "unprognostic (1.16e-1)" "unprognostic (1.08e-1)" "unprognostic (7.35e-2)" "unprognostic (7.72e-3)" LRCH3 MGC4126 ENSG00000186001 "Leucine rich repeats and calponin homology domain containing 3" Q96II8 3 197791226-197888436 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 39.0" "Lineage enriched" "Detected in all" 4 "granulocytes: 39.0" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012380, HPA017299" Uncertain Enhanced Cytosol NA NA "Cluster 32: Basophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 7: Non-specific - Transcription" 28 Cytosol "HPA012380: , HPA017299: " "unprognostic (3.62e-2)" "unprognostic (7.49e-3)" "unprognostic (3.07e-2)" "unprognostic (2.97e-3)" "unprognostic (4.98e-2)" "unprognostic (1.16e-1)" "unprognostic (1.40e-1)" "unprognostic (4.95e-3)" "unprognostic (8.71e-2)" "unprognostic (1.23e-2)" "unprognostic (2.28e-2)" "unprognostic (4.02e-3)" "unprognostic (1.35e-1)" "potential prognostic unfavorable (1.65e-4)" "unprognostic (1.46e-1)" "unprognostic (9.30e-2)" "potential prognostic unfavorable (6.02e-4)" "unprognostic (2.19e-1)" "unprognostic (1.62e-1)" "unprognostic (2.98e-3)" "unprognostic (6.92e-2)" "unprognostic (1.08e-1)" "unprognostic (8.23e-3)" "unprognostic (2.83e-2)" "unprognostic (4.68e-2)" "unprognostic (2.52e-1)" "unprognostic (9.51e-2)" "unprognostic (1.69e-1)" "unprognostic (1.20e-1)" "unprognostic (7.88e-2)" "unprognostic (1.44e-1)" LRCH4 "LRN, LRRN1" ENSG00000077454 "Leucine rich repeats and calponin homology domain containing 4" O75427 7 100574011-100586129 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 23.6;Bergmann glia: 13.3;Brain excitatory neurons: 13.4;Brain inhibitory neurons: 13.5;Choroid plexus epithelial cells: 14.3;Distal convoluted tubule cells: 12.8;Ependymal cells: 11.6;Epicardial cells: 13.6;Loop of henle epithelial cells: 13.4;Microglia: 14.1;Other brain neurons: 13.8;Papillary tip epithelial cells: 12.0;Podocytes: 20.1;Renal collecting duct intercalated cells: 18.2;Renal collecting duct principal cells: 13.7;Tuft cells: 23.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037667, HPA037668" Enhanced Approved "Nucleoplasm,Focal adhesion sites,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 39: Non-specific - Transcription" "Cluster 102: Non-specific - Mixed function" 23 "Nucleoplasm, Focal adhesion sites, Cytosol" "HPA037667: , HPA037668: " "unprognostic (3.92e-3)" "unprognostic (3.81e-2)" "unprognostic (4.12e-1)" "unprognostic (3.21e-1)" "unprognostic (3.74e-3)" "unprognostic (1.54e-2)" "unprognostic (4.14e-2)" "unprognostic (5.55e-2)" "unprognostic (5.37e-2)" "unprognostic (2.31e-1)" "potential prognostic unfavorable (7.17e-5)" "unprognostic (6.89e-2)" "potential prognostic favorable (3.73e-6)" "unprognostic (6.00e-2)" "unprognostic (1.69e-1)" "unprognostic (5.07e-2)" "unprognostic (2.43e-1)" "unprognostic (2.24e-1)" "unprognostic (5.23e-3)" "unprognostic (2.08e-2)" "unprognostic (4.25e-2)" "unprognostic (1.18e-3)" "unprognostic (5.61e-3)" "unprognostic (1.42e-1)" "potential prognostic unfavorable (6.37e-4)" "unprognostic (4.60e-2)" "unprognostic (2.61e-1)" "unprognostic (9.74e-2)" "unprognostic (9.83e-2)" "unprognostic (1.41e-1)" "unprognostic (2.30e-1)" LRCOL1 ENSG00000204583 "Leucine rich colipase like 1" A6NCL2 12 132603150-132610582 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 48 "epididymis: 47.3" "Cell type enriched" "Detected in some" 4 "Epididymal principal cells: 784.7" "Cell type enhanced" "Detected in some" "endothelial cell: 5.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Fibroblasts" "Not detected" "Not detected" "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 70: DU4475 - Unknown function" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" LRFN1 "KIAA1484, SALM2" ENSG00000128011 "Leucine rich repeat and fibronectin type III domain containing 1" Q9P244 19 39306566-39320863 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 14.3" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 9.7;Brain inhibitory neurons: 7.9;Müller glia: 7.9;Neutrophil progenitors: 7.4;Neutrophils: 33.8;Oligodendrocyte progenitor cells: 7.7;Other brain neurons: 10.9;Retinal amacrine cells: 11.0;Retinal bipolar cells: 27.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 27: Cerebellum - Synaptic function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 27 "unprognostic (1.66e-2)" "unprognostic (2.31e-2)" "unprognostic (2.57e-1)" "unprognostic (3.39e-3)" "unprognostic (6.55e-2)" "unprognostic (2.44e-1)" "unprognostic (1.11e-1)" "unprognostic (1.72e-1)" "unprognostic (2.42e-2)" "unprognostic (2.43e-1)" "unprognostic (3.84e-2)" "unprognostic (1.45e-1)" "potential prognostic unfavorable (1.05e-4)" "unprognostic (2.36e-3)" "unprognostic (1.59e-1)" "unprognostic (1.65e-1)" "unprognostic (8.63e-2)" "unprognostic (3.14e-3)" "unprognostic (5.35e-2)" "unprognostic (2.62e-3)" LRFN2 "FIGLER2, KIAA1246, SALM1" ENSG00000156564 "Leucine rich repeat and fibronectin type III domain containing 2" Q9ULH4 6 40391591-40587364 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 6.3;retina: 2.9" "Cell type enriched" "Detected in many" 8 "Cone photoreceptor cells: 865.3" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 2.1;Neuroblastoma: 4.2" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Beta cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA076660 Enhanced Supported "Plasma membrane" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 79: Photoreceptor cells - Phototransduction" "Plasma membrane" "HPA076660: " "unprognostic (6.02e-3)" "unprognostic (3.88e-3)" LRFN3 "FIGLER1, MGC2656, SALM4" ENSG00000126243 "Leucine rich repeat and fibronectin type III domain containing 3" Q9BTN0 19 35935358-35946624 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 19.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048923 Approved NA NA "Cluster 1: T-cells - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 19 "HPA048923: " "unprognostic (1.60e-2)" "unprognostic (2.29e-1)" "unprognostic (5.44e-2)" "unprognostic (8.43e-3)" "unprognostic (1.77e-1)" "unprognostic (1.20e-1)" "unprognostic (3.74e-1)" "unprognostic (2.68e-1)" "unprognostic (3.32e-1)" "unprognostic (1.14e-1)" "unprognostic (5.32e-2)" "unprognostic (7.76e-2)" "unprognostic (3.44e-2)" "unprognostic (5.56e-2)" "unprognostic (1.14e-1)" "unprognostic (3.81e-3)" "unprognostic (4.23e-2)" "unprognostic (5.79e-2)" "unprognostic (9.36e-2)" "unprognostic (1.07e-1)" "unprognostic (3.01e-2)" "unprognostic (1.56e-2)" "unprognostic (1.45e-1)" "unprognostic (3.25e-1)" "unprognostic (5.99e-2)" "unprognostic (2.13e-1)" "unprognostic (8.30e-2)" "unprognostic (3.14e-2)" "unprognostic (1.61e-1)" "unprognostic (6.25e-2)" "unprognostic (3.54e-1)" LRFN4 "FIGLER6, MGC3103, SALM3." ENSG00000173621 "Leucine rich repeat and fibronectin type III domain containing 4" Q6PJG9 11 66856647-66860475 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.4" "Cell type enhanced" "Detected in many" "Ependymal cells: 25.3;Late spermatids: 45.1;Podocytes: 26.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077570 Enhanced NA NA "Cluster 64: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 11 "HPA077570: " "unprognostic (8.15e-3)" "unprognostic (4.13e-2)" "unprognostic (4.85e-1)" "potential prognostic unfavorable (8.89e-4)" "unprognostic (5.88e-2)" "unprognostic (1.96e-1)" "unprognostic (4.88e-2)" "unprognostic (1.11e-1)" "unprognostic (8.53e-2)" "unprognostic (2.37e-1)" "unprognostic (1.96e-3)" "unprognostic (5.72e-2)" "unprognostic (1.30e-1)" "unprognostic (3.83e-3)" "unprognostic (1.04e-1)" "potential prognostic unfavorable (1.30e-4)" "unprognostic (9.57e-3)" "unprognostic (1.92e-1)" "unprognostic (3.39e-1)" "unprognostic (1.64e-2)" "unprognostic (1.50e-1)" "unprognostic (5.48e-2)" "unprognostic (3.51e-2)" "unprognostic (1.25e-1)" "unprognostic (3.90e-2)" "unprognostic (7.09e-3)" "unprognostic (5.32e-2)" "unprognostic (1.32e-3)" "unprognostic (2.06e-1)" "unprognostic (1.13e-1)" "unprognostic (1.11e-2)" LRFN5 "C14orf146, FIGLER8, SALM5" ENSG00000165379 "Leucine rich repeat and fibronectin type III domain containing 5" Q96NI6 14 41606876-41904549 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 9.8;cervix: 9.0;parathyroid gland: 10.5" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 174.0;Brain excitatory neurons: 634.5;Brain inhibitory neurons: 539.7;Fibro-adipogenic progenitors: 263.3;Leydig cells: 154.0;Oligodendrocyte progenitor cells: 467.2;Other brain neurons: 487.3;Retinal amacrine cells: 428.2;Retinal ganglion cells: 614.2;Smooth muscle cells: 171.3;Thyrotrophs: 215.0" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Kidney Chromophobe (TCGA): 6.9;Kidney Renal Papillary Cell Carcinoma (TCGA): 1.7;Testicular Germ Cell Tumor (TCGA): 2.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 5.8;Sarcoma: 3.2" "Breast - Fibroblasts, Colon - Colon enteroendocrine cells, Minor Salivary Gland - Fibroblasts, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblasts_2, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001177 Uncertain "Intracellular and membrane" "No annotated function" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 109: Neurons - Neuronal signaling" "HPA001177: " "unprognostic (1.90e-2)" "unprognostic (2.51e-3)" "unprognostic (3.62e-1)" "unprognostic (1.89e-2)" "unprognostic (5.53e-2)" "unprognostic (6.41e-2)" LRG1 LRG ENSG00000171236 "Leucine rich alpha-2-glycoprotein 1" P02750 19 4536402-4540036 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 20 "liver: 1004.2" "Cell type enhanced" "Detected in some" "Endometrial secretory cells: 1.9;Fallopian secretory cells: 1.6;Fallopian tube ciliated cells: 6.2;Hepatocytes: 3.8;Neutrophils: 5.9;Pancreatic duct cells: 1.4;Prostatic hillock cells: 1.3;Salivary acinar cells: 1.0" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "Liver Hepatocellular Carcinoma (TCGA): 226.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 19 "neutrophil: 285.0" "Lineage enriched" "Detected in many" 45 "granulocytes: 285.0" "Low cancer specificity" "Detected in many" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Kidney - Macrophages, Minor Salivary Gland - Minor salivary glandular cells, Spleen - Neutrophils_2" "Low region specificity" "Detected in single" "HPA001888, HPA001889" Enhanced Approved Vesicles "Secreted to blood" "No annotated function" NA NA 21000000000 12000000000 "Cluster 4: Neutrophils - Degranulation" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 48: Non-specific - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 7 Vesicles "HPA001888: , HPA001889: " "unprognostic (8.36e-2)" "unprognostic (3.04e-2)" "unprognostic (2.71e-1)" "unprognostic (2.48e-1)" "unprognostic (4.79e-2)" "unprognostic (8.46e-2)" "unprognostic (2.99e-1)" "unprognostic (1.48e-1)" "unprognostic (2.63e-1)" "unprognostic (6.28e-3)" "unprognostic (7.05e-2)" "unprognostic (2.69e-3)" "unprognostic (4.77e-2)" "potential prognostic favorable (2.39e-4)" "unprognostic (5.74e-2)" "unprognostic (1.41e-1)" "unprognostic (1.42e-1)" "unprognostic (3.26e-2)" "unprognostic (9.12e-2)" "unprognostic (3.77e-2)" "potential prognostic unfavorable (5.61e-4)" "unprognostic (1.02e-1)" "unprognostic (1.87e-1)" "unprognostic (3.09e-1)" "unprognostic (1.06e-2)" "unprognostic (1.68e-1)" "unprognostic (8.62e-2)" "unprognostic (1.10e-1)" "unprognostic (2.35e-3)" "unprognostic (1.62e-2)" LRGUK "CFAP246, FLJ32786" ENSG00000155530 "Leucine rich repeats and guanylate kinase domain containing" Q96M69 7 134127299-134264595 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 3.1;fallopian tube: 3.8;testis: 4.8" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 162.0;Endometrial ciliated cells: 295.3;Ependymal cells: 544.1;Epididymal efferent duct ciliated cells: 205.2;Fallopian tube ciliated cells: 199.8;Respiratory ciliated cells: 373.6;Respiratory ionocytes: 114.3;Salivary ionocytes: 156.0;Sertoli cells: 154.8" "Cell type enriched" "Detected in all" 4 "ependymal cell: 589.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 2.7" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA029505, HPA029506" Uncertain NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 11: Neuronal - Sensory perception" "Cluster 34: Ciliated cells - Cilia assembly & function" "HPA029505: , HPA029506: " "unprognostic (8.37e-2)" "unprognostic (6.91e-2)" "unprognostic (2.91e-1)" "unprognostic (4.41e-2)" "unprognostic (1.97e-1)" "unprognostic (8.23e-2)" "unprognostic (6.12e-2)" LRIF1 "C1orf103, FLJ11269, RIF1" ENSG00000121931 "Ligand dependent nuclear receptor interacting factor 1" Q5T3J3 1 110947190-110963965 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Breast lactating cells: 150.4;Epididymal principal cells: 188.4;Neutrophils: 138.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044515 Uncertain Supported "Nucleoplasm,Centriolar satellite" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 75: Non-specific - Chaperones and protein folding" 39 Nucleoplasm "Centriolar satellite" "HPA044515: " "unprognostic (2.77e-1)" "unprognostic (1.48e-1)" "unprognostic (3.82e-2)" "unprognostic (7.39e-2)" "unprognostic (1.77e-1)" "unprognostic (2.82e-2)" "unprognostic (6.20e-2)" "unprognostic (2.82e-1)" "potential prognostic unfavorable (7.62e-4)" "potential prognostic favorable (3.09e-5)" "unprognostic (4.82e-2)" "potential prognostic unfavorable (5.26e-4)" "unprognostic (1.40e-3)" "unprognostic (1.52e-1)" "potential prognostic unfavorable (1.89e-4)" "unprognostic (1.63e-1)" "unprognostic (2.94e-3)" "unprognostic (6.09e-2)" "unprognostic (2.07e-3)" "unprognostic (1.80e-1)" "unprognostic (7.85e-2)" "potential prognostic unfavorable (3.05e-4)" "unprognostic (1.73e-1)" "unprognostic (3.13e-1)" "unprognostic (1.53e-1)" "unprognostic (1.93e-1)" "unprognostic (1.84e-1)" "unprognostic (1.67e-1)" "unprognostic (1.57e-2)" "unprognostic (3.40e-1)" LRIG1 "DKFZP586O1624, LIG-1, LIG1" ENSG00000144749 "Leucine rich repeats and immunoglobulin like domains 1" Q96JA1 3 66378797-66501263 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 136.0" "Cell type enhanced" "Detected in many" "Adipocytes: 239.7;Astrocytes: 586.0;Bergmann glia: 324.0;Pancreatic acinar cells: 283.8;Pituitary stem cells: 459.6;Prostatic glandular cells: 191.4;Respiratory basal cells: 239.6;Respiratory deuterosomal cells: 222.9;Respiratory secretory cells: 196.3" "Cell type enhanced" "Detected in all" "astrocyte: 665.7;Bergmann glia: 365.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.1" "Lineage enhanced" "Detected in single" "T-cells: 1.1" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipocytes (Visceral), Adrenal gland - Fibroblasts, Breast - Breast glandular cells, Liver - Hepatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011846 Approved Approved Cytosol NA NA 47000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 60: Stomach - Digestion" "Cluster 19: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 28: Astrocytes - Homeostasis & neuron support" 14 Cytosol "HPA011846: " "unprognostic (7.64e-2)" "unprognostic (1.10e-1)" "unprognostic (2.44e-2)" "unprognostic (6.52e-3)" "unprognostic (1.59e-1)" "unprognostic (3.29e-1)" "unprognostic (2.08e-2)" "unprognostic (2.67e-2)" "unprognostic (1.46e-1)" "unprognostic (1.64e-2)" "potential prognostic favorable (6.53e-6)" "unprognostic (1.29e-2)" "unprognostic (5.28e-2)" "unprognostic (2.19e-1)" "unprognostic (2.78e-1)" "potential prognostic favorable (4.51e-4)" "unprognostic (1.88e-1)" "unprognostic (2.18e-1)" "unprognostic (2.22e-3)" "unprognostic (4.84e-1)" "unprognostic (1.62e-1)" "unprognostic (3.75e-1)" "potential prognostic favorable (9.44e-6)" "unprognostic (4.56e-1)" "unprognostic (3.97e-2)" "unprognostic (3.05e-3)" "unprognostic (1.54e-1)" "unprognostic (4.09e-1)" "unprognostic (2.07e-3)" "unprognostic (1.09e-1)" LRIG2 KIAA0806 ENSG00000198799 "Leucine rich repeats and immunoglobulin like domains 2" O94898 1 113073198-113132260 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 164.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015538 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA 500000 "Cluster 21: Neutrophils - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 7: Non-specific - Transcription" 25 "Golgi apparatus" Nucleoplasm "HPA015538: " "unprognostic (1.99e-2)" "unprognostic (1.20e-1)" "unprognostic (9.11e-2)" "unprognostic (1.50e-3)" "unprognostic (1.86e-1)" "unprognostic (1.15e-1)" "unprognostic (8.42e-2)" "unprognostic (9.73e-3)" "unprognostic (7.67e-3)" "unprognostic (7.35e-3)" "unprognostic (1.40e-2)" "unprognostic (2.81e-3)" "unprognostic (2.64e-2)" "unprognostic (2.18e-1)" "unprognostic (1.47e-1)" "unprognostic (5.61e-2)" "unprognostic (1.27e-2)" "unprognostic (1.49e-1)" "unprognostic (1.68e-1)" "unprognostic (8.79e-2)" "unprognostic (1.29e-1)" "unprognostic (5.31e-3)" "unprognostic (8.16e-2)" "potential prognostic favorable (9.30e-4)" "unprognostic (1.36e-1)" "unprognostic (9.55e-2)" "unprognostic (5.70e-2)" "unprognostic (1.12e-1)" "unprognostic (1.42e-1)" "unprognostic (2.39e-2)" LRIG3 "FLJ90440, KIAA3016" ENSG00000139263 "Leucine rich repeats and immunoglobulin like domains 3" Q6UXM1 12 58872149-58920504 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ependymal cells: 112.6;Lacrimal acinar cells: 202.0;Respiratory basal cells: 128.9" "Cell type enhanced" "Detected in many" "ependymal cell: 107.8;vascular associated smooth muscle cell: 67.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Prostate - Fibroblasts, Spleen - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010773 Approved Approved Cytosol NA NA "Cluster 58: Skin - Keratinization" "Cluster 3: Choroid plexus - Cilium" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 2 Cytosol "HPA010773: " "unprognostic (2.15e-1)" "unprognostic (2.00e-1)" "unprognostic (1.64e-1)" "unprognostic (3.10e-2)" "unprognostic (2.82e-2)" "unprognostic (1.99e-1)" "unprognostic (1.65e-1)" "unprognostic (2.57e-1)" "unprognostic (7.40e-2)" "unprognostic (1.24e-2)" "potential prognostic favorable (1.48e-4)" "unprognostic (2.52e-3)" "unprognostic (5.26e-2)" "unprognostic (1.02e-2)" "unprognostic (8.22e-2)" "unprognostic (4.26e-2)" "unprognostic (1.41e-1)" "unprognostic (1.28e-2)" "unprognostic (1.86e-1)" "unprognostic (2.65e-2)" "unprognostic (7.81e-3)" "unprognostic (6.98e-3)" "unprognostic (1.28e-1)" "unprognostic (1.80e-1)" "unprognostic (8.69e-3)" "unprognostic (6.58e-2)" "unprognostic (6.19e-2)" "unprognostic (3.66e-2)" "unprognostic (2.49e-1)" "unprognostic (5.57e-2)" "unprognostic (2.22e-1)" LRIT1 "DKFZP434K091, FIGLER9, LRRC21, PAL" ENSG00000148602 "Leucine rich repeat, Ig-like and transmembrane domains 1" Q9P2V4 10 84231520-84241546 "Predicted membrane proteins" "Sensory transduction, Vision" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "retina: 23.8" "Group enriched" "Detected in some" 4 "Early spermatids: 25.3;Late primary spermatocytes: 44.3;Late spermatids: 53.0;Retinal bipolar cells: 14.0" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "choroid plexus: 1.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA014296 Approved "Flagellar centriole" NA NA "Cluster 42: Retina - Visual perception" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "Flagellar centriole" "HPA014296: " LRIT2 "AC022389.4, LRRC22" ENSG00000204033 "Leucine rich repeat, Ig-like and transmembrane domains 2" A6NDA9 10 84220571-84225544 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "retina: 54.7" "Group enriched" "Detected in some" 4 "Retinal bipolar cells: 9.7;Retinal pigment epithelial cells: 12.8;Rod photoreceptor cells: 30.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enterocytes, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Not detected" "Not detected" HPA037788 Enhanced NA NA "Cluster 42: Retina - Visual perception" "Cluster 23: Choroid plexus - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 79: Photoreceptor cells - Phototransduction" "HPA037788: " LRIT3 "CSNB1F, FIGLER4, FLJ44691" ENSG00000183423 "Leucine rich repeat, Ig-like and transmembrane domains 3" Q3SXY7 4 109848107-109872315 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Sensory transduction, Vision" "Congenital stationary night blindness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 18 "retina: 16.3" "Group enriched" "Detected in some" 4 "Cone photoreceptor cells: 8.3;Ependymal cells: 4.5;Müller glia: 17.7;Retinal pigment epithelial cells: 17.1;Rod photoreceptor cells: 7.5" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in single" 4 "Kidney Chromophobe (TCGA): 1.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA013454 Enhanced Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 42: Retina - Visual perception" "Cluster 53: Neurons - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" "Nucleoplasm, Mitochondria, Cytosol" "HPA013454: " "unprognostic (1.32e-1)" "unprognostic (5.43e-2)" "unprognostic (9.98e-2)" LRMDA "C10orf11, CDA017, OCA7" ENSG00000148655 "Leucine rich melanocyte differentiation associated" Q9H2I8 10 75431624-76560168 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Differentiation Albinism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 61.5" "Cell type enhanced" "Detected in all" "Adrenal cortex cells: 3456.5;Bergmann glia: 2005.5;Distal convoluted tubule cells: 2009.3;Microglia: 4340.8;Monocyte progenitors: 1809.3;Neutrophil progenitors: 1677.8;Proximal tubule cells: 2352.3;Renal collecting duct intercalated cells: 2042.8;Renal connecting tubule cells: 1934.7" "Cell type enhanced" "Detected in all" "Bergmann glia: 1857.7;central nervous system macrophage: 5604.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 58.0;eosinophil: 22.2;intermediate monocyte: 28.9;myeloid DC: 67.6;non-classical monocyte: 17.3" "Group enriched" "Detected in many" 7 "dendritic cells: 67.6;granulocytes: 22.2;monocytes: 58.0" "Cancer enhanced" "Detected in many" "skin cancer: 22.7" "Breast - Endothelial cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Minor Salivary Gland - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA047446, HPA050419" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 76: Non-specific - Metabolism" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" Nucleoplasm Cytosol "HPA047446: , HPA050419: " "unprognostic (1.49e-2)" "unprognostic (9.66e-2)" "unprognostic (3.87e-2)" "unprognostic (2.11e-1)" "unprognostic (7.19e-2)" "unprognostic (7.23e-3)" "unprognostic (1.47e-1)" "unprognostic (4.50e-2)" "unprognostic (1.18e-2)" "unprognostic (1.34e-2)" "unprognostic (2.40e-1)" "potential prognostic favorable (4.96e-4)" "unprognostic (7.04e-2)" "unprognostic (1.61e-2)" "unprognostic (4.19e-2)" "unprognostic (4.37e-1)" "potential prognostic unfavorable (9.68e-5)" "unprognostic (7.98e-2)" "unprognostic (1.46e-1)" "unprognostic (2.17e-1)" "unprognostic (2.24e-2)" "unprognostic (2.51e-1)" "unprognostic (9.97e-2)" "unprognostic (2.15e-1)" "unprognostic (2.84e-1)" "unprognostic (1.58e-1)" "unprognostic (1.46e-1)" "unprognostic (5.50e-2)" "unprognostic (2.53e-1)" LRP1 "A2MR, APOER, APR, CD91, IGFBP-3R, IGFBP3R1, LRP, LRP1A" ENSG00000123384 "LDL receptor related protein 1" Q07954 12 57128483-57213361 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Endocytosis, Host-virus interaction" "Developmental protein, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 102.4" "Cell type enhanced" "Detected in many" "Adipocytes: 513.4;Fibro-adipogenic progenitors: 289.7;Fibroblasts: 444.0;Hepatocytes: 236.8;Kupffer cells: 253.2;Leydig cells: 345.4;monocytes: 220.6;Oligodendrocyte progenitor cells: 334.9;Peritubular myoid cells: 279.1" "Cell type enhanced" "Detected in all" "fibroblast: 578.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 18 "classical monocyte: 4.3;intermediate monocyte: 2.2;myeloid DC: 1.6;non-classical monocyte: 2.5" "Group enriched" "Detected in many" 21 "dendritic cells: 1.6;monocytes: 4.3" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatocytes, Lung - Fibroblasts_2, Prostate - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004182, CAB018621, HPA022903" Supported Supported "Nucleoli,Plasma membrane,Cytosol" "Intracellular and membrane" Receptor NA NA 220000000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 44: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 31 "Plasma membrane" "Nucleoli, Cytosol" "CAB018621: , HPA004182: , HPA022903: " "unprognostic (3.21e-1)" "unprognostic (2.13e-1)" "unprognostic (1.61e-2)" "unprognostic (6.96e-2)" "unprognostic (1.36e-1)" "unprognostic (2.56e-1)" "unprognostic (2.17e-1)" "unprognostic (5.13e-3)" "unprognostic (1.74e-1)" "unprognostic (1.05e-1)" "potential prognostic favorable (4.04e-4)" "unprognostic (1.95e-1)" "unprognostic (6.28e-2)" "unprognostic (1.21e-1)" "unprognostic (1.94e-3)" "unprognostic (1.07e-1)" "unprognostic (1.90e-2)" "unprognostic (2.41e-2)" "unprognostic (4.01e-1)" "unprognostic (4.34e-3)" "unprognostic (2.26e-1)" "unprognostic (1.77e-1)" "unprognostic (2.78e-2)" "unprognostic (3.18e-1)" "unprognostic (3.51e-1)" "unprognostic (2.25e-3)" "unprognostic (1.33e-1)" "unprognostic (4.14e-3)" "unprognostic (1.35e-1)" "unprognostic (1.58e-2)" "unprognostic (1.48e-1)" LRP10 "DKFZP564C1940, LRP9, MGC8675, MST087, MSTP087" ENSG00000197324 "LDL receptor related protein 10" Q7Z4F1 14 22871740-22881713 "Predicted membrane proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 1224.4;Esophageal suprabasal cells: 303.9;Neutrophils: 677.4" "Cell type enhanced" "Detected in many" "vascular associated smooth muscle cell: 52.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 59.2" "Lineage enriched" "Detected in all" 5 "granulocytes: 59.2" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Macrophages, Pituitary gland - Endothelial cells, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000932 Approved Nucleoplasm,Nucleoli NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 24: Neutrophils - Innate immunity signal integration" 38 Nucleoplasm Nucleoli "HPA000932: " "unprognostic (8.63e-2)" "unprognostic (1.33e-1)" "unprognostic (8.06e-2)" "potential prognostic unfavorable (2.42e-4)" "unprognostic (6.98e-2)" "unprognostic (4.80e-2)" "unprognostic (2.68e-1)" "unprognostic (5.27e-3)" "unprognostic (9.74e-2)" "unprognostic (1.01e-1)" "potential prognostic favorable (2.38e-7)" "unprognostic (2.06e-1)" "unprognostic (1.72e-2)" "potential prognostic unfavorable (9.31e-5)" "unprognostic (3.65e-2)" "unprognostic (3.25e-2)" "unprognostic (5.39e-3)" "potential prognostic unfavorable (1.12e-4)" "unprognostic (2.08e-1)" "unprognostic (6.34e-3)" "unprognostic (1.63e-1)" "unprognostic (1.19e-2)" "unprognostic (2.30e-1)" "unprognostic (1.82e-1)" "unprognostic (1.35e-1)" "unprognostic (2.15e-1)" "unprognostic (2.75e-1)" "unprognostic (1.87e-2)" "unprognostic (3.70e-2)" "unprognostic (5.65e-2)" "unprognostic (8.10e-2)" LRP11 "bA350J20.3, MANSC3" ENSG00000120256 "LDL receptor related protein 11" Q86VZ4 6 149818757-149864359 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 35.2;Brain inhibitory neurons: 35.0;Choroid plexus epithelial cells: 23.1;Distal convoluted tubule cells: 22.8;Early spermatids: 29.9;Ependymal cells: 71.1;Late spermatids: 68.6;Loop of henle epithelial cells: 18.3;Oligodendrocytes: 27.0;Other brain neurons: 33.1;Papillary tip epithelial cells: 48.9;Podocytes: 84.7;Proximal tubule cells: 17.6;Renal collecting duct intercalated cells: 49.6;Renal collecting duct principal cells: 20.5;Renal connecting tubule cells: 19.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017267 Approved "Vesicles,Plasma membrane" NA NA 740000 "Cluster 73: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 7: Liver cancer - Metabolism" "Cluster 104: Brain endothelial cells - Blood brain barrier" 1 "Plasma membrane" Vesicles "HPA017267: " "unprognostic (1.58e-1)" "potential prognostic unfavorable (7.20e-7)" "unprognostic (6.21e-2)" "unprognostic (6.37e-3)" "unprognostic (1.05e-1)" "unprognostic (8.27e-2)" "unprognostic (5.12e-2)" "unprognostic (2.42e-1)" "unprognostic (4.50e-3)" "unprognostic (4.39e-1)" "potential prognostic favorable (3.69e-4)" "unprognostic (3.18e-3)" "potential prognostic unfavorable (9.92e-4)" "validated prognostic unfavorable (3.55e-5)" "validated prognostic unfavorable (3.11e-4)" "unprognostic (1.43e-2)" "unprognostic (2.22e-1)" "unprognostic (2.03e-1)" "unprognostic (7.83e-3)" "unprognostic (1.91e-1)" "unprognostic (1.38e-1)" "unprognostic (1.83e-1)" "unprognostic (2.09e-2)" "unprognostic (2.78e-1)" "unprognostic (2.13e-1)" "unprognostic (1.42e-1)" "unprognostic (9.63e-2)" "unprognostic (3.36e-1)" "unprognostic (3.27e-2)" "unprognostic (4.02e-2)" "unprognostic (1.46e-3)" LRP12 "FLJ12929, ST7" ENSG00000147650 "LDL receptor related protein 12" Q9Y561 8 104489231-104589258 "Disease related genes, Human disease related genes, Predicted membrane proteins" Endocytosis Receptor "Amyotrophic lateral sclerosis, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 90.6;Brain inhibitory neurons: 105.6;Lactotrophs: 87.3;Platelets: 176.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 8 "basophil: 47.2" "Lineage enriched" "Detected in many" 32 "granulocytes: 47.2" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017245 Uncertain Approved "Nucleoli fibrillar center,Plasma membrane,Mitochondria" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 29: Forebrain - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 35: Neurons - Synaptic function & neurogenesis" 4 "Nucleoli fibrillar center, Plasma membrane, Mitochondria" "HPA017245: " "unprognostic (8.17e-2)" "unprognostic (2.07e-1)" "unprognostic (1.50e-1)" "unprognostic (2.34e-2)" "unprognostic (3.79e-1)" "unprognostic (5.45e-3)" "unprognostic (1.99e-1)" "unprognostic (2.08e-3)" "unprognostic (1.56e-2)" "unprognostic (7.66e-3)" "potential prognostic favorable (5.59e-5)" "unprognostic (1.06e-1)" "unprognostic (2.50e-1)" "unprognostic (1.93e-3)" "unprognostic (1.39e-1)" "unprognostic (7.38e-3)" "unprognostic (6.40e-3)" "unprognostic (7.83e-2)" "unprognostic (1.58e-1)" "unprognostic (3.83e-2)" "unprognostic (1.15e-2)" "unprognostic (1.03e-1)" "unprognostic (4.95e-3)" "unprognostic (8.19e-2)" "unprognostic (3.68e-1)" "unprognostic (7.72e-2)" "unprognostic (2.43e-1)" "unprognostic (3.18e-3)" "unprognostic (2.20e-1)" "unprognostic (8.34e-2)" "unprognostic (8.49e-2)" LRP1B "LRP-DIT, LRPDIT" ENSG00000168702 "LDL receptor related protein 1B" Q9NZR2 2 140231423-142131016 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Endocytosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.4;thyroid gland: 5.3" "Cell type enhanced" "Detected in many" "Astrocytes: 4292.7;Bergmann glia: 4281.2;Brain excitatory neurons: 3314.8;Brain inhibitory neurons: 2318.8;Ependymal cells: 1416.4;Lactotrophs: 3235.0;Oligodendrocyte progenitor cells: 7072.9;Oligodendrocytes: 1743.4;Other brain neurons: 3835.1;Pituicytes/FSCs: 2918.7;Pituitary stem cells: 2020.2;Retinal ganglion cells: 2078.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 6.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 3.3" "Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069094, HPA074788" Approved Approved Vesicles NA NA 98000 "Cluster 78: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 3: Rhabdoid - Membrane components" "Cluster 109: Neurons - Neuronal signaling" 4 Vesicles "HPA069094: , HPA074788: " "unprognostic (3.31e-3)" "unprognostic (3.27e-1)" "unprognostic (1.00e-1)" "unprognostic (2.85e-3)" "unprognostic (1.18e-2)" LRP2 "DBS, gp330" ENSG00000081479 "LDL receptor related protein 2" P98164 2 169127109-169362534 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Endocytosis, Hearing, Neurogenesis, Transport" Receptor "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 32.5;parathyroid gland: 42.1;retina: 27.1" "Cell type enriched" "Detected in many" 4 "Proximal tubule cells: 1481.7" "Cell type enriched" "Detected in many" 4 "oligodendrocyte: 498.7" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 33.4;Kidney Renal Papillary Cell Carcinoma (TCGA): 25.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 7.3" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Kidney - Proximal tubular cells, Lung - Alveolar cells type 2, Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA005980, HPA064792" Enhanced Uncertain "Cell Junctions" NA NA 670000 "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 88: Proximal tubular cells - Transmembrane transport" 19 "Cell Junctions" "HPA005980: , HPA064792: " "unprognostic (2.94e-1)" "unprognostic (7.40e-2)" "unprognostic (1.33e-2)" "unprognostic (8.30e-2)" "potential prognostic favorable (8.48e-9)" "unprognostic (1.21e-3)" "unprognostic (1.51e-2)" "unprognostic (3.61e-2)" "unprognostic (7.71e-2)" "unprognostic (3.34e-1)" "unprognostic (2.91e-2)" "unprognostic (1.69e-1)" "unprognostic (1.52e-2)" "unprognostic (2.63e-2)" LRP2BP DKFZp761O0113 ENSG00000109771 "LRP2 binding protein" Q9P2M1 4 185363872-185395924 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 16.4;retina: 26.8" "Cell type enhanced" "Detected in many" "Bergmann glia: 103.8;Cone photoreceptor cells: 101.4;Ependymal cells: 248.6;Epicardial cells: 204.7;Retinal bipolar cells: 102.1" "Cell type enhanced" "Detected in all" "ependymal cell: 274.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Lung - Alveolar cells type 2, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA036664, HPA036665" Approved Uncertain "Golgi apparatus" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 2: Neurons - Nucleosome" "Cluster 55: Lymphoma - Immune response" "Cluster 34: Ciliated cells - Cilia assembly & function" 18 "Golgi apparatus" "HPA036664: , HPA036665: " "unprognostic (1.52e-1)" "unprognostic (1.83e-1)" "unprognostic (2.46e-2)" "unprognostic (3.85e-2)" "unprognostic (1.93e-2)" "unprognostic (2.01e-1)" "unprognostic (9.03e-2)" "unprognostic (1.01e-1)" "unprognostic (1.06e-1)" "unprognostic (1.94e-2)" "potential prognostic favorable (1.43e-4)" "unprognostic (1.08e-3)" "unprognostic (3.03e-2)" "unprognostic (1.02e-1)" "unprognostic (1.12e-1)" "potential prognostic favorable (6.62e-4)" "unprognostic (4.04e-2)" "unprognostic (6.43e-2)" "unprognostic (5.00e-2)" "unprognostic (1.24e-1)" "unprognostic (1.54e-1)" "unprognostic (1.19e-1)" "unprognostic (8.61e-2)" LRP3 "hLRp105, LRP-3" ENSG00000130881 "LDL receptor related protein 3" O75074 19 33177603-33208864 "Predicted intracellular proteins, Predicted membrane proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 76.5" "Cell type enhanced" "Detected in many" "Astrocytes: 21.2;Brain excitatory neurons: 29.1;Brain inhibitory neurons: 31.0;Breast myoepithelial cells: 25.0;Oligodendrocyte progenitor cells: 27.4;Other brain neurons: 27.2;Retinal amacrine cells: 25.4;Retinal bipolar cells: 22.0;Retinal ganglion cells: 38.6;Retinal horizontal cells: 20.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Minor Salivary Gland - Smooth muscle cells, Skin - Fibroblasts_2, Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041658 Approved "Lipid droplets" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 1 "Lipid droplets" "HPA041658: " "unprognostic (1.13e-1)" "unprognostic (2.40e-1)" "unprognostic (1.92e-1)" "unprognostic (1.05e-1)" "unprognostic (1.67e-1)" "unprognostic (1.84e-1)" "unprognostic (2.94e-1)" "unprognostic (2.63e-1)" "unprognostic (5.37e-2)" "unprognostic (1.09e-1)" "potential prognostic favorable (8.64e-4)" "unprognostic (2.19e-1)" "unprognostic (8.49e-2)" "unprognostic (2.40e-1)" "unprognostic (3.80e-2)" "unprognostic (2.49e-1)" "unprognostic (1.25e-1)" "unprognostic (1.22e-1)" "unprognostic (1.86e-1)" "unprognostic (1.53e-1)" "unprognostic (1.42e-1)" "potential prognostic favorable (1.17e-4)" "unprognostic (1.43e-1)" "unprognostic (9.40e-2)" "unprognostic (7.44e-3)" "unprognostic (7.12e-2)" "unprognostic (6.29e-2)" "unprognostic (3.33e-1)" "unprognostic (1.17e-1)" "unprognostic (1.25e-2)" "unprognostic (9.43e-2)" LRP4 "CLSS, LRP-4, MEGF7, SOST2" ENSG00000134569 "LDL receptor related protein 4" O75096 11 46856717-46918642 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Endocytosis, Wnt signaling pathway" "Developmental protein, Receptor" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.3;skin 1: 29.8" "Cell type enhanced" "Detected in many" "Astrocytes: 167.8;Bergmann glia: 110.8;Cone photoreceptor cells: 200.8;Oligodendrocyte progenitor cells: 214.9;Papillary tip epithelial cells: 111.1;Pituicytes/FSCs: 305.5" "Cell type enhanced" "Detected in many" "astrocyte: 176.6;Bergmann glia: 129.4;oligodendrocyte precursor cell: 251.1" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 25.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other), Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011934, HPA012300" Approved Uncertain Nucleoplasm,Mitochondria NA NA "Cluster 2: Non-specific - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 8 Mitochondria Nucleoplasm "HPA011934: , HPA012300: " "unprognostic (4.25e-2)" "unprognostic (5.95e-2)" "unprognostic (1.02e-1)" "unprognostic (1.86e-2)" "unprognostic (1.84e-1)" "unprognostic (3.90e-2)" "unprognostic (5.42e-2)" "unprognostic (2.09e-2)" "unprognostic (6.53e-2)" "unprognostic (5.53e-3)" "validated prognostic favorable (2.64e-6)" "validated prognostic favorable (3.75e-4)" "unprognostic (3.26e-2)" "potential prognostic unfavorable (5.81e-4)" "unprognostic (6.70e-2)" "unprognostic (5.45e-2)" "unprognostic (4.45e-2)" "unprognostic (9.14e-3)" "unprognostic (5.26e-2)" "unprognostic (2.83e-1)" "unprognostic (1.57e-1)" "unprognostic (5.06e-3)" "unprognostic (1.34e-2)" "unprognostic (3.01e-2)" "unprognostic (1.38e-1)" "unprognostic (4.95e-2)" "unprognostic (1.05e-1)" "unprognostic (1.32e-2)" LRP5 "BMND1, EVR1, EVR4, HBM, LR3, LRP7, OPPG, OPS, OPTA1, VBCH2" ENSG00000162337 "LDL receptor related protein 5" O75197 11 68312591-68449275 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Endocytosis, Wnt signaling pathway" "Developmental protein, Receptor" "Disease variant, Osteogenesis imperfecta, Osteopetrosis, Osteoporosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 122.3" "Low cell type specificity" "Detected in many" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 61.2;endothelial cell: 51.6;ependymal cell: 46.3" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "choroid plexus: 91.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013001, HPA030505" Enhanced NA NA 9200000 "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 36: Choroid plexus - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 43 "CAB013001: , HPA030505: " "unprognostic (2.38e-2)" "unprognostic (1.41e-1)" "unprognostic (4.40e-2)" "unprognostic (2.62e-3)" "unprognostic (3.64e-1)" "unprognostic (2.66e-1)" "unprognostic (3.89e-1)" "unprognostic (1.16e-1)" "unprognostic (3.14e-2)" "unprognostic (1.04e-1)" "potential prognostic favorable (1.73e-10)" "unprognostic (4.93e-3)" "unprognostic (6.39e-2)" "unprognostic (2.38e-1)" "unprognostic (2.82e-2)" "unprognostic (8.22e-2)" "unprognostic (6.39e-2)" "unprognostic (7.34e-2)" "unprognostic (9.20e-2)" "unprognostic (3.76e-1)" "unprognostic (1.84e-1)" "unprognostic (2.80e-1)" "unprognostic (3.09e-1)" "unprognostic (1.43e-2)" "unprognostic (1.65e-1)" "unprognostic (1.68e-1)" "unprognostic (7.24e-2)" "unprognostic (1.30e-1)" "unprognostic (1.62e-1)" "unprognostic (4.07e-2)" "unprognostic (1.45e-1)" LRP6 ADCAD2 ENSG00000070018 "LDL receptor related protein 6" O75581 12 12116025-12267044 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Endocytosis, Wnt signaling pathway" "Developmental protein, Receptor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 137.0;Bergmann glia: 96.5;Brain excitatory neurons: 71.7;Brain inhibitory neurons: 73.3;Choroid plexus epithelial cells: 238.3;Distal convoluted tubule cells: 237.5;Ependymal cells: 194.3;Loop of henle epithelial cells: 152.0;Oligodendrocyte progenitor cells: 173.6;Oligodendrocytes: 185.7;Other brain neurons: 68.6;Podocytes: 100.1;Proximal tubule cells: 110.6;Renal collecting duct intercalated cells: 126.9;Renal collecting duct principal cells: 72.0;Renal connecting tubule cells: 109.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in all" 5 "Bile duct cancer: 56.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004490, HPA029925" Enhanced NA NA 460000 "Cluster 75: Ovary - Mixed function" "Cluster 36: Choroid plexus - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 102: Non-specific - Mixed function" 66 "CAB004490: , HPA029925: " "unprognostic (1.06e-1)" "unprognostic (1.72e-1)" "unprognostic (1.18e-1)" "unprognostic (4.46e-2)" "unprognostic (1.36e-1)" "unprognostic (4.68e-3)" "unprognostic (5.51e-2)" "unprognostic (3.18e-2)" "unprognostic (1.97e-1)" "unprognostic (4.45e-3)" "validated prognostic favorable (7.25e-6)" "validated prognostic favorable (4.16e-5)" "unprognostic (1.10e-1)" "unprognostic (1.40e-1)" "unprognostic (8.77e-2)" "unprognostic (2.33e-1)" "unprognostic (1.90e-1)" "unprognostic (9.22e-2)" "unprognostic (3.83e-2)" "unprognostic (6.50e-2)" "unprognostic (1.41e-1)" "unprognostic (2.18e-1)" "unprognostic (5.80e-2)" "unprognostic (7.77e-2)" "unprognostic (7.34e-3)" "unprognostic (3.36e-1)" "unprognostic (1.60e-1)" "unprognostic (1.74e-1)" "unprognostic (3.70e-1)" "unprognostic (1.42e-2)" "unprognostic (6.28e-2)" LRP8 "APOER2, HSZ75190, LRP-8, MCI1" ENSG00000157193 "LDL receptor related protein 8" Q14114 1 53242364-53328469 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Endocytosis, Host-virus interaction" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 22.5;thyroid gland: 38.8" "Group enriched" "Detected in many" 4 "Retinal pigment epithelial cells: 601.1;Sertoli cells: 199.3" "Cell type enhanced" "Detected in all" "MGE interneuron: 249.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Pituitary gland - Corticotropes, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073031 Enhanced "Secreted in other tissues" Receptor NA NA 20000000 "Cluster 20: Non-specific - DNA binding" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" 18 "HPA073031: " "unprognostic (1.32e-1)" "unprognostic (9.36e-3)" "unprognostic (1.03e-2)" "unprognostic (3.92e-3)" "unprognostic (1.07e-1)" "unprognostic (2.26e-1)" "unprognostic (3.84e-1)" "unprognostic (2.23e-3)" "unprognostic (3.77e-2)" "unprognostic (1.95e-2)" "validated prognostic unfavorable (1.69e-9)" "validated prognostic unfavorable (2.64e-4)" "potential prognostic unfavorable (1.18e-6)" "unprognostic (8.73e-2)" "potential prognostic unfavorable (2.34e-4)" "unprognostic (1.19e-1)" "unprognostic (6.39e-3)" "unprognostic (1.12e-3)" "unprognostic (5.50e-2)" "unprognostic (8.79e-2)" "unprognostic (9.35e-2)" "unprognostic (1.45e-1)" "unprognostic (1.28e-1)" "unprognostic (1.64e-2)" "unprognostic (4.47e-2)" "unprognostic (2.60e-1)" "unprognostic (4.81e-3)" "unprognostic (1.33e-1)" "unprognostic (7.93e-2)" "unprognostic (8.15e-2)" LRPAP1 "A2MRAP, HBP44, RAP" ENSG00000163956 "LDL receptor related protein associated protein 1" P30533 4 3503612-3532446 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Heparin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 669.8;Decidual stromal cells: 469.3;Epididymal principal cells: 449.3;Migrating cytotrophoblasts: 528.0;Syncytiotrophoblasts: 857.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Macrophages, Minor Salivary Gland - Minor salivary glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008001, CAB025518, HPA073239" Enhanced Supported Enhanced "Endoplasmic reticulum" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 70: Non-specific - Protein processing" "Cluster 23: Choroid plexus - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 37 "Endoplasmic reticulum" "CAB025518: , HPA008001: , HPA073239: " "unprognostic (5.64e-2)" "unprognostic (1.13e-2)" "unprognostic (1.04e-1)" "unprognostic (2.52e-1)" "potential prognostic favorable (6.43e-4)" "unprognostic (1.28e-2)" "unprognostic (3.16e-3)" "unprognostic (2.29e-2)" "unprognostic (1.44e-1)" "unprognostic (2.46e-2)" "potential prognostic favorable (6.33e-5)" "unprognostic (3.78e-2)" "potential prognostic favorable (1.90e-5)" "unprognostic (1.17e-3)" "unprognostic (2.18e-3)" "unprognostic (4.19e-2)" "unprognostic (5.49e-2)" "unprognostic (2.69e-2)" "unprognostic (4.24e-2)" "unprognostic (1.97e-1)" "unprognostic (7.12e-2)" "potential prognostic favorable (2.92e-5)" "unprognostic (1.26e-1)" "unprognostic (3.87e-1)" "unprognostic (1.18e-1)" "unprognostic (4.53e-2)" "unprognostic (2.06e-1)" "unprognostic (3.06e-1)" "unprognostic (2.35e-1)" "unprognostic (7.92e-2)" "unprognostic (3.46e-1)" LRPPRC "GP130, LRP130, LSFC" ENSG00000138095 "Leucine rich pentatricopeptide repeat containing" P42704 2 43886224-43996226 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Autophagy, mRNA transport, Transcription, Transcription regulation, Transport" "DNA-binding, RNA-binding" "Disease variant, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033786, HPA036408, HPA036409" Enhanced Enhanced "Mitochondria,Acrosome,Mid piece,End piece" No No 290000 "Cluster 16: Non-specific - Cell proliferation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 17: Non-specific - RNA processing" 92 Mitochondria "Acrosome, Mid piece, End piece" "CAB033786: , HPA036408: , HPA036409: " "unprognostic (7.11e-2)" "unprognostic (7.52e-2)" "unprognostic (1.45e-1)" "unprognostic (1.94e-1)" "unprognostic (5.14e-2)" "unprognostic (7.66e-2)" "unprognostic (3.51e-1)" "unprognostic (1.26e-1)" "unprognostic (8.75e-2)" "unprognostic (7.23e-3)" "potential prognostic favorable (6.12e-7)" "unprognostic (5.39e-3)" "unprognostic (3.41e-1)" "validated prognostic unfavorable (1.22e-5)" "validated prognostic unfavorable (1.47e-5)" "unprognostic (3.79e-2)" "potential prognostic unfavorable (3.67e-4)" "unprognostic (4.56e-3)" "unprognostic (3.91e-2)" "unprognostic (1.43e-1)" "unprognostic (7.88e-2)" "unprognostic (1.35e-2)" "unprognostic (6.40e-2)" "unprognostic (5.39e-2)" "unprognostic (3.12e-2)" "unprognostic (6.13e-2)" "unprognostic (2.08e-1)" "unprognostic (1.29e-1)" "unprognostic (2.53e-1)" "unprognostic (6.69e-3)" "unprognostic (1.87e-2)" LRR1 "LRR-1, MGC20689, PPIL5" ENSG00000165501 "Leucine rich repeat protein 1" Q96L50 14 49598761-49614672 "Essential proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 27.2" "Cell type enhanced" "Detected in many" "Early spermatids: 103.9;Erythrocyte progenitors: 68.7;Late primary spermatocytes: 345.6;Late spermatids: 52.9" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 9.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA065703, HPA069364" Approved Approved "Nucleoplasm,Nuclear membrane,Vesicles" No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 39: Testis - Nuclear processes" "Cluster 45: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 17 "Nucleoplasm, Nuclear membrane" Vesicles "HPA065703: , HPA069364: " "unprognostic (8.03e-2)" "unprognostic (1.19e-2)" "unprognostic (2.01e-1)" "unprognostic (1.55e-3)" "unprognostic (1.16e-1)" "unprognostic (1.22e-1)" "unprognostic (1.86e-2)" "unprognostic (9.94e-2)" "potential prognostic unfavorable (9.29e-7)" "unprognostic (5.74e-3)" "unprognostic (6.78e-2)" "unprognostic (1.59e-1)" "unprognostic (1.24e-3)" "potential prognostic unfavorable (6.87e-7)" "unprognostic (2.07e-3)" "unprognostic (3.50e-2)" "unprognostic (2.01e-3)" "unprognostic (1.74e-1)" "unprognostic (8.39e-2)" "unprognostic (3.78e-2)" "unprognostic (1.01e-2)" "unprognostic (4.91e-3)" "unprognostic (7.40e-2)" "unprognostic (1.79e-1)" "unprognostic (2.05e-2)" "unprognostic (4.10e-2)" "unprognostic (8.00e-2)" "unprognostic (1.69e-1)" "unprognostic (1.76e-1)" "unprognostic (1.08e-1)" LRRC1 "dJ523E19.1, FLJ10775, FLJ11834, LANO" ENSG00000137269 "Leucine rich repeat containing 1" Q9BTT6 6 53794497-53924125 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 244.5;Endometrial glandular cells: 237.1;Lymphatic endothelial cells: 246.2;Pituicytes/FSCs: 254.7" "Cell type enhanced" "Detected in all" "oligodendrocyte: 289.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 1, Skeletal muscle - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031603, HPA031604" Enhanced Supported Cytosol NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 20 Cytosol "HPA031603: , HPA031604: " "unprognostic (6.70e-2)" "unprognostic (1.19e-1)" "unprognostic (1.04e-1)" "unprognostic (5.55e-2)" "unprognostic (1.80e-3)" "unprognostic (3.36e-2)" "unprognostic (3.52e-1)" "potential prognostic favorable (3.03e-4)" "unprognostic (1.03e-1)" "unprognostic (5.73e-2)" "validated prognostic favorable (4.79e-7)" "validated prognostic favorable (6.93e-5)" "unprognostic (1.48e-1)" "unprognostic (1.12e-3)" "potential prognostic unfavorable (7.77e-5)" "unprognostic (2.54e-2)" "unprognostic (5.10e-3)" "unprognostic (1.41e-3)" "unprognostic (3.33e-1)" "unprognostic (5.33e-2)" "unprognostic (3.35e-1)" "potential prognostic unfavorable (9.45e-5)" "unprognostic (1.02e-1)" "unprognostic (2.23e-1)" "unprognostic (7.44e-2)" "unprognostic (1.43e-1)" "unprognostic (5.99e-2)" "unprognostic (3.10e-1)" "unprognostic (1.66e-1)" "unprognostic (7.23e-2)" "unprognostic (6.56e-2)" LRRC10 "HRLRRP, LRRC10A" ENSG00000198812 "Leucine rich repeat containing 10" Q5BKY1 12 69608564-69610907 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 55 "heart muscle: 37.4" "Group enriched" "Detected in some" 29 "Adipocytes: 1.7;Cardiomyocytes: 4.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 5 LRRC10B ENSG00000204950 "Leucine rich repeat containing 10B" A6NIK2 11 61508749-61511018 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 59.2;fallopian tube: 27.0;pituitary gland: 31.9" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 56.9;Ependymal cells: 32.4;Epididymal efferent duct ciliated cells: 49.5;Fallopian tube ciliated cells: 179.1;Pancreatic islet cells: 32.8;Respiratory ciliated cells: 225.3;Vascular smooth muscle cells: 38.3" "Cell type enhanced" "Detected in many" "ependymal cell: 37.9;medium spiny neuron: 20.7;vascular associated smooth muscle cell: 24.0" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 7.4" "Region enhanced" "Detected in many" "basal ganglia: 90.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 4.0;Sarcoma: 3.6" "Heart muscle - Smooth muscle cells, Lung - Respiratory ciliated cells, Pancreas - Beta cells, Pituitary gland - Somatotropes, Skeletal muscle - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in many" 7 "basal ganglia: 222.6" "Group enriched" "Detected in many" 5 "basal ganglia: 40.7;hippocampal formation: 31.6" HPA047619 Uncertain Approved Nucleoplasm,Nucleoli No NA "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 107: Ciliated cells - Cilia assembly & function" Nucleoplasm Nucleoli "HPA047619: " "unprognostic (1.05e-1)" "unprognostic (6.40e-2)" "unprognostic (1.39e-3)" "unprognostic (4.36e-2)" "unprognostic (9.86e-2)" "unprognostic (2.22e-1)" "unprognostic (2.42e-3)" "unprognostic (6.19e-2)" "potential prognostic favorable (6.64e-4)" "unprognostic (2.36e-3)" "unprognostic (1.95e-1)" "unprognostic (3.08e-2)" "unprognostic (2.31e-1)" "unprognostic (1.88e-2)" "unprognostic (1.53e-2)" "unprognostic (1.73e-1)" "unprognostic (6.74e-2)" "unprognostic (1.81e-2)" "unprognostic (7.64e-2)" "unprognostic (6.26e-2)" LRRC14 "KIAA0014, LRRC14A" ENSG00000160959 "Leucine rich repeat containing 14" Q15048 8 144517992-144525172 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 29.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021047 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 67: Plasma cells - Plasma cell differentiation" 9 "Nucleoplasm, Cytosol" "HPA021047: " "unprognostic (3.49e-1)" "unprognostic (8.21e-2)" "unprognostic (1.66e-1)" "potential prognostic unfavorable (7.03e-4)" "unprognostic (3.10e-1)" "unprognostic (2.65e-1)" "unprognostic (4.31e-2)" "unprognostic (4.00e-2)" "unprognostic (6.57e-2)" "unprognostic (2.75e-2)" "unprognostic (7.78e-3)" "unprognostic (9.39e-2)" "unprognostic (2.48e-2)" "potential prognostic unfavorable (5.74e-4)" "unprognostic (3.52e-2)" "unprognostic (2.39e-1)" "unprognostic (1.04e-1)" "unprognostic (5.79e-2)" "unprognostic (1.26e-2)" "unprognostic (1.96e-1)" "unprognostic (7.89e-2)" "unprognostic (1.64e-3)" "unprognostic (8.33e-3)" "unprognostic (5.48e-2)" "unprognostic (3.31e-2)" "unprognostic (1.94e-1)" "unprognostic (5.84e-2)" "unprognostic (4.91e-2)" "unprognostic (2.03e-1)" "unprognostic (3.32e-2)" "unprognostic (2.06e-1)" LRRC14B ENSG00000185028 "Leucine rich repeat containing 14B" A6NHZ5 5 191495-196334 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 4 "heart muscle: 39.2;skeletal muscle: 106.6" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 9.6;Myonuclei: 14.7;Oocytes: 4.6;Retinal ganglion cells: 11.6;Retinal horizontal cells: 6.0" "Cell type enhanced" "Detected in single" "mammillary body: 1.6" "Cancer enriched" "Detected in some" 21 "Kidney Chromophobe (TCGA): 26.7" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 14 "plasmacytoid DC: 1.6" "Lineage enriched" "Detected in single" 14 "dendritic cells: 1.6" "Group enriched" "Detected in some" 16 "Leukemia: 9.4;lymphoma: 5.8;Myeloma: 16.2" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA038046, HPA038047" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 19: Astrocytes - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 55: Myocytes - Oxidative muscle function" "Nucleoplasm, Cytosol" "HPA038046: , HPA038047: " "potential prognostic unfavorable (4.55e-4)" "unprognostic (3.02e-1)" "unprognostic (7.30e-2)" "unprognostic (5.90e-3)" LRRC15 LIB ENSG00000172061 "Leucine rich repeat containing 15" Q8TF66 3 194355249-194369743 "Plasma proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 4.6;skin 1: 6.7" "Cell type enhanced" "Detected in some" "Epicardial cells: 2.3;Fibroblasts: 2.8;Hepatic stellate cells: 6.5;Lymphatic endothelial cells: 11.0;Schwann cells: 2.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 40.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 6.6;Brain cancer: 17.0" "Adipose subcutaneous - Adipose progenitor cells, Minor Salivary Gland - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Thyroid gland - Fibroblasts" "Not detected" "Not detected" "Not detected" "Not detected" HPA035503 Uncertain Approved "Vesicles,Plasma membrane" NA NA 640000 "Cluster 58: Skin - Keratinization" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 1 Vesicles "Plasma membrane" "HPA035503: " "unprognostic (1.01e-2)" "unprognostic (2.86e-2)" "unprognostic (5.35e-2)" "unprognostic (1.05e-2)" "unprognostic (2.66e-1)" "unprognostic (4.64e-3)" "potential prognostic unfavorable (6.83e-6)" "unprognostic (2.01e-1)" "unprognostic (1.09e-1)" "potential prognostic unfavorable (1.74e-5)" "unprognostic (5.05e-2)" "unprognostic (9.32e-3)" "unprognostic (2.35e-1)" "unprognostic (1.07e-1)" "unprognostic (2.10e-2)" "potential prognostic unfavorable (1.34e-4)" "unprognostic (3.17e-2)" "unprognostic (4.45e-1)" "unprognostic (1.98e-1)" "unprognostic (6.51e-3)" "unprognostic (2.82e-1)" "unprognostic (7.15e-2)" "unprognostic (1.48e-3)" "unprognostic (1.23e-1)" LRRC17 "H_RG318M05.3, P37NB" ENSG00000128606 "Leucine rich repeat containing 17" Q8N6Y2 7 102913000-102945111 "Predicted secreted proteins" Osteogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 92.6" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 201.0;Epicardial cells: 63.7;Gastric chief cells: 146.3;Granulosa cells: 72.2;Hepatic stellate cells: 71.0;Leydig cells: 103.1;Mucous neck cells: 57.1;Oocytes: 64.5;Ovarian stromal cells: 181.9;Parietal cells: 60.1" "Cell type enhanced" "Detected in all" "endothelial cell: 77.6;fibroblast: 81.2" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 21.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 94 "eosinophil: 9.9" "Lineage enriched" "Detected in single" 94 "granulocytes: 9.9" "Cancer enhanced" "Detected in many" "Brain cancer: 51.0;Sarcoma: 69.5" "Adipose subcutaneous - Adipose progenitor cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblasts_2, Minor Salivary Gland - Fibroblasts, Pituitary gland - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Chief cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA073458 Approved "Vesicles,Cytokinetic bridge" "Secreted in other tissues" Other Yes NA "Cluster 22: Eosinophils - Transcription" "Cluster 75: Ovary - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 94: Gonadal somatic cells - Mixed function" 9 Vesicles "Cytokinetic bridge" "HPA073458: " "unprognostic (2.85e-1)" "unprognostic (3.86e-1)" "unprognostic (1.35e-1)" "unprognostic (1.46e-1)" "unprognostic (5.07e-2)" "unprognostic (2.18e-1)" "unprognostic (3.99e-1)" "unprognostic (3.47e-1)" "unprognostic (2.69e-1)" "unprognostic (6.14e-2)" "unprognostic (2.82e-3)" "potential prognostic favorable (9.55e-4)" "unprognostic (8.38e-3)" "unprognostic (9.91e-2)" "unprognostic (1.49e-1)" "unprognostic (8.92e-2)" "unprognostic (1.09e-1)" "unprognostic (1.12e-2)" "unprognostic (4.28e-2)" "unprognostic (9.49e-3)" "unprognostic (2.33e-2)" "unprognostic (2.01e-1)" "unprognostic (1.63e-1)" "unprognostic (3.12e-1)" "unprognostic (1.62e-1)" "unprognostic (7.00e-2)" "unprognostic (1.71e-3)" "unprognostic (3.73e-2)" "unprognostic (1.38e-2)" "unprognostic (2.70e-1)" LRRC18 "MGC34773, UNQ933, UNQ9338, VKGE9338" ENSG00000165383 "Leucine rich repeat containing 18" Q8N456 10 48909480-48939840 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "choroid plexus: 23.2;fallopian tube: 6.2;testis: 12.8" "Group enriched" "Detected in some" 4 "cDC: 11.9;Early spermatids: 8.4;Late primary spermatocytes: 6.0;Late spermatids: 10.4;Respiratory ciliated cells: 4.3" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in all" 8 "choroid plexus: 23.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Skin - Fibroblasts_1, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA039256, HPA076699" Enhanced Approved Cytosol NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 2 Cytosol "HPA039256: , HPA076699: " "unprognostic (1.72e-2)" LRRC19 FLJ21302 ENSG00000184434 "Leucine rich repeat containing 19" Q9H756 9 26993136-27005672 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "intestine: 33.9;kidney: 40.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 28.0;Colonocytes: 129.4;Enteric stem cells: 23.9;Enteric transient amplifying cells: 41.4;Enterocytes: 97.5;Epicardial cells: 29.6;Epididymal efferent duct absorptive cells: 20.4;Goblet cells: 23.5;Proximal tubule cells: 27.5;Renal collecting duct principal cells: 24.5;Tuft cells: 23.1" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Colon Adenocarcinoma (TCGA): 7.7;Kidney Renal Clear Cell Carcinoma (TCGA): 6.5;Kidney Renal Papillary Cell Carcinoma (TCGA): 14.3;Rectum Adenocarcinoma (TCGA): 8.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "colorectal cancer: 1.6" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Pancreas - Ductal cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA 230000 "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" "unprognostic (1.37e-3)" "unprognostic (1.40e-2)" "unprognostic (4.21e-1)" "validated prognostic favorable (2.84e-9)" "validated prognostic favorable (4.97e-5)" "potential prognostic favorable (7.46e-5)" "unprognostic (1.13e-2)" "unprognostic (1.94e-1)" "unprognostic (4.38e-3)" "potential prognostic unfavorable (3.02e-4)" "unprognostic (1.15e-1)" LRRC2 ENSG00000163827 "Leucine rich repeat containing 2" Q9BYS8 3 46515385-46606948 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "heart muscle: 42.9;skeletal muscle: 154.3;tongue: 88.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 177.0;Medullary thymic epithelial cells: 79.2;Myonuclei: 769.5;Podocytes: 551.8;Thymic myoid cells: 176.8" "Cell type enhanced" "Detected in many" "upper-layer intratelencephalic: 52.3" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 9.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Heart muscle - Cardiomyocytes, Spleen - Endothelial cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA039138, HPA064844" Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 51: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 55: Myocytes - Oxidative muscle function" Nucleoplasm "Nuclear bodies, Cytosol" "HPA039138: , HPA064844: " "unprognostic (6.17e-2)" "unprognostic (8.67e-2)" "unprognostic (2.57e-1)" "unprognostic (6.12e-2)" "unprognostic (2.20e-2)" "unprognostic (6.75e-3)" "unprognostic (3.09e-3)" "unprognostic (1.41e-2)" "unprognostic (1.20e-2)" "unprognostic (2.89e-1)" "unprognostic (7.09e-2)" "unprognostic (3.22e-2)" "unprognostic (3.94e-2)" "unprognostic (3.02e-2)" "unprognostic (1.01e-1)" "unprognostic (2.15e-2)" "unprognostic (1.83e-1)" LRRC20 "FLJ10751, FLJ10844" ENSG00000172731 "Leucine rich repeat containing 20" Q8TCA0 10 70298970-70382650 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "skeletal muscle: 286.3;tongue: 116.7" "Cell type enhanced" "Detected in many" "Early spermatids: 39.1;Esophageal apical cells: 101.2;Gonadotrophs: 43.6;Late primary spermatocytes: 61.6;Late spermatids: 91.0;Myonuclei: 111.8;Somatotrophs: 38.3;Thyrotrophs: 46.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Pituitary gland - Gonadotropes, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039630 Approved Nucleoplasm,Cytosol No No "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 4 Nucleoplasm Cytosol "HPA039630: " "unprognostic (5.60e-3)" "unprognostic (2.68e-2)" "unprognostic (5.93e-2)" "unprognostic (1.01e-2)" "unprognostic (1.28e-1)" "unprognostic (3.11e-1)" "unprognostic (4.10e-2)" "potential prognostic favorable (2.91e-4)" "unprognostic (2.41e-2)" "potential prognostic unfavorable (3.16e-4)" "unprognostic (2.19e-1)" "unprognostic (4.62e-3)" "potential prognostic favorable (3.53e-6)" "unprognostic (1.20e-1)" "unprognostic (1.52e-1)" "unprognostic (1.48e-1)" "unprognostic (2.32e-1)" "unprognostic (9.50e-3)" "unprognostic (2.53e-1)" "unprognostic (2.85e-1)" "unprognostic (1.20e-1)" "unprognostic (1.01e-1)" "unprognostic (5.37e-2)" "unprognostic (1.80e-1)" "unprognostic (1.00e-1)" "unprognostic (6.00e-2)" "unprognostic (3.28e-1)" "unprognostic (1.27e-3)" "unprognostic (1.07e-1)" "unprognostic (6.03e-2)" "unprognostic (1.98e-2)" LRRC23 "B7, LRPB7" ENSG00000010626 "Leucine rich repeat containing 23" Q53EV4 12 6873569-6914241 "Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "fallopian tube: 95.7" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 239.0;Ependymal cells: 177.0;Epididymal basal cells: 148.2;Epididymal efferent duct ciliated cells: 222.4;Fallopian tube ciliated cells: 297.8;Respiratory ciliated cells: 337.6" "Cell type enriched" "Detected in all" 4 "ependymal cell: 202.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA037766, HPA057533" Enhanced Approved "Nucleoli,Nucleoli rim" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 27: Breast cancer - Unknown function" "Cluster 107: Ciliated cells - Cilia assembly & function" 1 "Nucleoli, Nucleoli rim" "HPA037766: , HPA057533: " "unprognostic (4.81e-2)" "unprognostic (9.88e-2)" "unprognostic (5.19e-3)" "unprognostic (2.47e-3)" "unprognostic (2.02e-2)" "unprognostic (5.89e-2)" "unprognostic (1.28e-1)" "unprognostic (2.09e-2)" "unprognostic (1.77e-2)" "unprognostic (5.53e-3)" "unprognostic (8.65e-2)" "unprognostic (6.18e-2)" "potential prognostic favorable (1.08e-4)" "potential prognostic unfavorable (3.72e-5)" "unprognostic (2.18e-1)" "unprognostic (7.96e-2)" "unprognostic (1.78e-1)" "unprognostic (2.06e-1)" "unprognostic (2.04e-1)" "unprognostic (1.82e-1)" "unprognostic (2.85e-1)" "unprognostic (7.99e-2)" "potential prognostic unfavorable (2.50e-4)" "unprognostic (1.20e-2)" "unprognostic (3.01e-3)" "unprognostic (2.39e-1)" "unprognostic (3.73e-1)" "unprognostic (2.82e-1)" "unprognostic (5.48e-2)" "unprognostic (6.72e-2)" "unprognostic (1.74e-2)" LRRC24 LRRC14OS ENSG00000254402 "Leucine rich repeat containing 24" Q50LG9 8 144522388-144527033 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 12.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 29.7;Cone photoreceptor cells: 35.2;Early spermatids: 22.4;Late primary spermatocytes: 27.8;Late spermatids: 114.6;Pancreatic islet cells: 34.5;Retinal bipolar cells: 60.9;Retinal horizontal cells: 22.0;Rod photoreceptor cells: 35.6" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 9.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028171, HPA052250" Enhanced Approved Vesicles NA NA "Cluster 64: Non-specific - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 2 Vesicles "HPA028171: , HPA052250: " "unprognostic (1.67e-1)" "unprognostic (1.19e-1)" "unprognostic (3.86e-2)" "unprognostic (2.84e-1)" "unprognostic (3.47e-2)" "unprognostic (5.10e-2)" "unprognostic (6.54e-2)" "unprognostic (1.56e-3)" "unprognostic (1.73e-2)" "unprognostic (5.07e-2)" "unprognostic (2.41e-1)" "unprognostic (3.09e-3)" "unprognostic (1.76e-1)" "unprognostic (2.69e-2)" "unprognostic (5.19e-3)" "unprognostic (1.05e-1)" "unprognostic (1.77e-1)" LRRC25 "FLJ38116, MAPA" ENSG00000175489 "Leucine rich repeat containing 25" Q8N386 19 18391137-18397622 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 31.0;lymphoid tissue: 58.6" "Cell type enhanced" "Detected in some" "cDC: 41.7;Hofbauer cells: 32.0;Kupffer cells: 131.2;Macrophages: 54.5;Monocyte progenitors: 35.5;monocytes: 105.6;Neutrophil progenitors: 27.6;Neutrophils: 170.5;pDCs: 26.4" "Group enriched" "Detected in some" 39 "central nervous system macrophage: 14.0;leukocyte: 15.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "classical monocyte: 320.9;eosinophil: 357.0;intermediate monocyte: 512.1;myeloid DC: 229.7;neutrophil: 574.9;non-classical monocyte: 710.4" "Group enriched" "Detected in all" 60 "dendritic cells: 229.7;granulocytes: 574.9;monocytes: 710.4" "Cancer enhanced" "Detected in some" "Leukemia: 2.3;lymphoma: 2.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Skin - Macrophages, Spleen - Macrophages, Stomach - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA029459 Approved Approved "Endoplasmic reticulum,Microtubules,Cytosol" NA NA 37000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 90 "Endoplasmic reticulum, Microtubules, Cytosol" "HPA029459: " "unprognostic (5.24e-1)" "unprognostic (7.11e-2)" "unprognostic (8.32e-2)" "unprognostic (2.51e-1)" "unprognostic (1.10e-1)" "unprognostic (3.00e-1)" "unprognostic (3.89e-2)" "unprognostic (2.41e-1)" "unprognostic (1.23e-1)" "unprognostic (5.76e-3)" "unprognostic (2.59e-2)" "unprognostic (1.36e-1)" "unprognostic (4.14e-2)" "unprognostic (1.53e-2)" "unprognostic (6.51e-2)" "unprognostic (1.91e-2)" "unprognostic (2.68e-2)" "unprognostic (5.58e-2)" "unprognostic (1.70e-1)" "unprognostic (5.44e-2)" "unprognostic (2.62e-1)" "unprognostic (1.37e-1)" "unprognostic (1.64e-1)" "unprognostic (1.24e-1)" "unprognostic (3.63e-2)" "potential prognostic favorable (4.27e-4)" "unprognostic (2.06e-2)" "unprognostic (1.09e-1)" "unprognostic (3.34e-3)" "unprognostic (1.33e-1)" "unprognostic (1.93e-1)" LRRC26 bA350O14.10 ENSG00000184709 "Leucine rich repeat containing 26" Q2I0M4 9 137168758-137170051 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "salivary gland: 285.7" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 74.9;Breast lactating cells: 112.7;Breast secretory cells: 116.5;Gastric chief cells: 131.0;Goblet cells: 582.6;Lacrimal acinar cells: 317.9;pDCs: 113.0;Prostatic glandular cells: 180.2;Salivary acinar cells: 259.4;Salivary duct cells: 159.2" "Cell type enriched" "Detected in some" 5 "upper rhombic lip: 9.6" "Cancer enriched" "Detected in many" 6 "Prostate Adenocarcinoma (TCGA): 92.6" "Region enhanced" "Detected in many" "cerebellum: 6.5" "Immune cell enriched" "Detected in single" 1179 "plasmacytoid DC: 117.8" "Lineage enriched" "Detected in single" 1179 "dendritic cells: 117.8" "Group enriched" "Detected in many" 4 "breast cancer: 19.6;prostate cancer: 35.9" "Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA056312 Approved Supported "Nucleoli fibrillar center,Plasma membrane" NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 82: Salivary gland - Secretion" "Cluster 15: Non-specific - Transcription" "Cluster 60: Prostate cancer - Unknown function" "Cluster 70: Intestinal goblet cells - Mucin production" "Plasma membrane" "Nucleoli fibrillar center" "HPA056312: " "unprognostic (2.41e-1)" "unprognostic (3.61e-2)" "unprognostic (6.69e-2)" "unprognostic (1.70e-2)" "unprognostic (9.35e-3)" "unprognostic (1.99e-2)" "unprognostic (3.30e-1)" "unprognostic (4.84e-2)" "unprognostic (6.38e-2)" "unprognostic (1.46e-3)" "unprognostic (1.20e-1)" "unprognostic (7.22e-2)" "unprognostic (4.24e-3)" "potential prognostic favorable (1.91e-4)" "unprognostic (9.70e-2)" LRRC27 KIAA1674 ENSG00000148814 "Leucine rich repeat containing 27" Q9C0I9 10 132332154-132381508 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "testis: 72.0" "Group enriched" "Detected in many" 7 "Early spermatids: 540.9;Late primary spermatocytes: 454.7;Late spermatids: 1552.2" "Cell type enhanced" "Detected in all" "ependymal cell: 129.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA037595, HPA067395" Enhanced Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 29: Forebrain - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" "Golgi apparatus" Nucleoplasm "HPA037595: , HPA067395: " "unprognostic (8.70e-2)" "unprognostic (1.77e-1)" "unprognostic (9.17e-2)" "unprognostic (1.15e-2)" "unprognostic (1.99e-1)" "unprognostic (3.54e-1)" "unprognostic (5.17e-2)" "unprognostic (2.02e-2)" "unprognostic (2.80e-2)" "unprognostic (1.73e-1)" "potential prognostic favorable (2.92e-4)" "unprognostic (2.56e-1)" "unprognostic (2.92e-3)" "unprognostic (2.80e-2)" "unprognostic (1.71e-2)" "unprognostic (3.98e-3)" "unprognostic (8.36e-2)" "unprognostic (1.96e-1)" "unprognostic (2.02e-1)" "unprognostic (2.15e-2)" "unprognostic (2.71e-2)" "potential prognostic favorable (5.51e-4)" "unprognostic (2.21e-2)" "unprognostic (4.39e-1)" "unprognostic (3.07e-2)" "unprognostic (3.04e-3)" "unprognostic (3.40e-1)" "unprognostic (3.29e-2)" "unprognostic (3.32e-1)" "unprognostic (1.71e-1)" "unprognostic (1.20e-1)" LRRC28 "FLJ34269, FLJ45242, MGC24976" ENSG00000168904 "Leucine rich repeat containing 28" Q86X40 15 99251362-99390729 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 44.0" "Cell type enhanced" "Detected in many" "Late spermatids: 635.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "HPA039378, HPA040784, HPA066130" Approved Approved "Nucleoplasm,Golgi apparatus,Mitochondria" No No "Cluster 42: Non-specific - Vesicular transport" "Cluster 76: Non-specific - Metabolism" "Cluster 53: Neurons - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 3 Nucleoplasm "Golgi apparatus, Mitochondria" "HPA039378: , HPA040784: , HPA066130: " "unprognostic (2.06e-1)" "unprognostic (1.29e-1)" "unprognostic (2.78e-1)" "unprognostic (2.45e-1)" "unprognostic (6.26e-2)" "unprognostic (6.20e-2)" "unprognostic (1.45e-2)" "unprognostic (2.38e-1)" "unprognostic (5.62e-3)" "unprognostic (1.01e-1)" "validated prognostic favorable (4.76e-10)" "validated prognostic favorable (6.95e-4)" "unprognostic (2.55e-1)" "unprognostic (1.71e-1)" "unprognostic (9.94e-3)" "unprognostic (2.87e-2)" "unprognostic (1.86e-1)" "unprognostic (8.22e-2)" "unprognostic (4.42e-1)" "potential prognostic favorable (4.44e-4)" "unprognostic (4.46e-2)" "unprognostic (8.20e-2)" "unprognostic (1.44e-1)" "unprognostic (1.37e-1)" "unprognostic (5.29e-2)" "unprognostic (5.16e-2)" "unprognostic (9.90e-3)" "unprognostic (1.20e-2)" "unprognostic (1.93e-1)" "unprognostic (7.61e-3)" "potential prognostic favorable (7.70e-4)" LRRC3 "C21orf102, C21orf30, DKFZP434C128, LRRC3DN" ENSG00000160233 "Leucine rich repeat containing 3" Q9BY71 21 44455510-44462196 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 15.1" "Cell type enhanced" "Detected in some" "Extravillous trophoblasts: 9.6;Gastric progenitor cells: 6.4;Hepatocytes: 34.9" "Cell type enhanced" "Detected in some" "vascular associated smooth muscle cell: 2.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Liver - Hepatocytes, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA017975 Uncertain NA NA "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" "HPA017975: " "unprognostic (4.16e-3)" "potential prognostic unfavorable (8.38e-4)" "unprognostic (3.73e-1)" "unprognostic (4.59e-2)" "unprognostic (1.05e-1)" "unprognostic (6.98e-2)" "unprognostic (2.00e-2)" "potential prognostic unfavorable (2.62e-6)" "unprognostic (1.03e-3)" "unprognostic (4.19e-3)" "potential prognostic favorable (4.43e-5)" "unprognostic (2.14e-1)" "unprognostic (3.72e-1)" "unprognostic (1.63e-1)" "unprognostic (1.05e-1)" "unprognostic (2.30e-2)" "unprognostic (1.29e-1)" "unprognostic (2.08e-1)" "unprognostic (1.27e-2)" "unprognostic (7.15e-2)" "unprognostic (2.64e-1)" "unprognostic (3.86e-1)" "unprognostic (1.38e-2)" "unprognostic (1.86e-1)" "unprognostic (1.38e-2)" LRRC30 ENSG00000206422 "Leucine rich repeat containing 30" A6NM36 18 7231089-7232044 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 20 "skeletal muscle: 14.8;tongue: 4.0" "Cell type enriched" "Detected in single" 5 "Myonuclei: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" HPA041039 Uncertain NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" "HPA041039: " LRRC31 FLJ23259 ENSG00000114248 "Leucine rich repeat containing 31" Q6UY01 3 169839172-169869935 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 20.4;salivary gland: 5.9;stomach 1: 9.5" "Cell type enhanced" "Detected in some" "Colonocytes: 19.4;Enteric stem cells: 15.8;Enteric transient amplifying cells: 14.3;Foveolar cells: 11.5;Gastric chief cells: 52.4;Gastric progenitor cells: 25.6;Goblet cells: 57.8;Mucous neck cells: 32.3;Paneth cells: 15.5;Parietal cells: 26.5" "Cell type enhanced" "Detected in some" "cerebellar inhibitory: 4.6;ependymal cell: 2.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "breast cancer: 4.1;colorectal cancer: 3.9;Gastric cancer: 2.4" "Colon - Colon enterocytes, Liver - Hepatocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA058013 Approved Nucleoplasm,Cytosol NA NA "Cluster 77: Intestine - Digestion" "Cluster 27: Breast cancer - Unknown function" "Cluster 70: Intestinal goblet cells - Mucin production" 1 Nucleoplasm Cytosol "HPA058013: " "unprognostic (4.46e-2)" "unprognostic (1.95e-1)" "unprognostic (5.08e-1)" "unprognostic (1.35e-1)" "unprognostic (1.73e-3)" "unprognostic (7.61e-2)" "unprognostic (9.46e-2)" "unprognostic (8.70e-2)" "unprognostic (3.39e-2)" "unprognostic (2.29e-1)" "unprognostic (9.99e-3)" "unprognostic (3.05e-3)" "unprognostic (1.95e-2)" "unprognostic (3.59e-3)" "unprognostic (4.20e-2)" "unprognostic (2.35e-1)" "unprognostic (8.98e-3)" LRRC32 "D11S833E, GARP" ENSG00000137507 "Leucine rich repeat containing 32" Q14392 11 76657524-76670747 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Growth factor binding" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 243.7;Fibroblasts: 24.2;Hepatic stellate cells: 64.5;Lymphatic endothelial cells: 27.0;Pericytes: 49.9;Vascular endothelial cells: 173.9;Vascular smooth muscle cells: 61.4" "Group enriched" "Detected in some" 17 "endothelial cell: 74.0;pericyte: 66.5;vascular associated smooth muscle cell: 78.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 2.2" "Lineage enhanced" "Detected in single" "T-cells: 2.2" "Group enriched" "Detected in many" 4 "Bone cancer: 4.0;lymphoma: 11.0;Sarcoma: 8.6;testis cancer: 7.0" "Breast - Endothelial cells, Colon - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA055775, HPA058434" Enhanced Nucleoplasm "Intracellular and membrane" Other NA NA 30000 "Cluster 28: Neutrophils - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 12 Nucleoplasm "HPA055775: , HPA058434: " "unprognostic (1.33e-1)" "unprognostic (1.09e-1)" "unprognostic (2.48e-1)" "unprognostic (1.72e-3)" "unprognostic (1.52e-2)" "potential prognostic unfavorable (2.96e-4)" "unprognostic (6.61e-2)" "unprognostic (5.17e-2)" "unprognostic (5.50e-2)" "unprognostic (3.80e-2)" "validated prognostic favorable (3.69e-5)" "validated prognostic favorable (1.63e-4)" "unprognostic (3.95e-2)" "unprognostic (9.79e-2)" "potential prognostic favorable (9.98e-4)" "unprognostic (2.15e-1)" "unprognostic (2.12e-2)" "unprognostic (2.66e-3)" "unprognostic (2.60e-1)" "unprognostic (5.14e-3)" "unprognostic (8.44e-2)" "unprognostic (1.29e-1)" "unprognostic (1.06e-1)" "unprognostic (1.28e-1)" "unprognostic (3.73e-1)" "unprognostic (1.01e-2)" "potential prognostic unfavorable (9.69e-4)" "unprognostic (2.98e-3)" "unprognostic (1.58e-1)" "potential prognostic unfavorable (8.00e-4)" "unprognostic (4.48e-2)" LRRC34 MGC27085 ENSG00000171757 "Leucine rich repeat containing 34" Q8IZ02 3 169793003-169812986 "Predicted intracellular proteins" Differentiation "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 11.9" "Cell type enhanced" "Detected in many" "Early spermatids: 106.4;Ependymal cells: 79.0;Epididymal efferent duct ciliated cells: 72.2;Fallopian tube ciliated cells: 93.8;Late primary spermatocytes: 264.6;Respiratory ciliated cells: 134.4" "Cell type enhanced" "Detected in all" "ependymal cell: 92.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.6" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Prostate - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA035747 Approved Approved "Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Basal body" Yes NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 21: Non-specific - Metabolism" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" Microtubules "Cytokinetic bridge, Mitotic spindle, Primary cilium, Basal body" "HPA035747: " "unprognostic (1.85e-1)" "unprognostic (4.25e-3)" "validated prognostic unfavorable (8.00e-4)" "validated prognostic unfavorable (1.63e-5)" "unprognostic (1.12e-1)" "unprognostic (4.35e-1)" "unprognostic (8.69e-2)" "unprognostic (1.64e-2)" "unprognostic (3.09e-2)" "unprognostic (6.54e-3)" "unprognostic (1.23e-1)" "unprognostic (1.18e-1)" LRRC36 FLJ11004 ENSG00000159708 "Leucine rich repeat containing 36" Q1X8D7 16 67326798-67385204 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 33.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 65.1;Early primary spermatocytes: 169.8;Early spermatids: 295.0;Endometrial ciliated cells: 67.4;Epididymal efferent duct ciliated cells: 57.9;Fallopian tube ciliated cells: 69.9;Late primary spermatocytes: 145.1;Late spermatids: 166.0;pDCs: 72.6;Respiratory ciliated cells: 75.6;Retinal ganglion cells: 85.0" "Cell type enhanced" "Detected in many" "ependymal cell: 32.1" "Cancer enhanced" "Detected in single" "Kidney Renal Papillary Cell Carcinoma (TCGA): 1.6" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 7 "plasmacytoid DC: 9.8" "Lineage enriched" "Detected in many" 7 "dendritic cells: 9.8" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA055237, HPA058479" Enhanced Approved Vesicles,Mitochondria NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 3: Early primary spermatocytes - Early meiosis" Mitochondria Vesicles "HPA055237: , HPA058479: " "unprognostic (1.70e-1)" "unprognostic (6.55e-2)" "unprognostic (3.12e-2)" "unprognostic (3.42e-3)" "unprognostic (2.12e-1)" "unprognostic (4.17e-2)" LRRC37A KIAA0563 ENSG00000176681 "Leucine rich repeat containing 37A" A6NMS7 17 46292733-46338077 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 11.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 28.4;Distal convoluted tubule cells: 12.2;Early spermatids: 32.6;Epicardial cells: 40.9" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA042121, HPA043056, HPA045090, HPA049080" Supported Approved Vesicles NA NA "Cluster 67: Testis - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" Vesicles "HPA042121: , HPA043056: , HPA045090: , HPA049080: " "unprognostic (3.57e-2)" "unprognostic (4.75e-2)" "unprognostic (2.96e-1)" "unprognostic (3.76e-1)" "unprognostic (1.15e-3)" "unprognostic (2.59e-2)" LRRC37A2 FLJ45049 ENSG00000238083 "Leucine rich repeat containing 37 member A2" A6NM11 17 46511508-46556910 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 9 "testis: 6.5" "Cell type enhanced" "Detected in many" "Astrocytes: 23.0;Distal convoluted tubule cells: 37.8;Early spermatids: 29.2;Ependymal cells: 28.1;Epicardial cells: 36.4;Loop of henle epithelial cells: 35.8;Papillary tip epithelial cells: 36.7;Podocytes: 29.7;Proximal tubule cells: 25.4;Renal collecting duct intercalated cells: 32.5;Renal collecting duct principal cells: 38.0;Renal connecting tubule cells: 31.3" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.7" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "HPA042121, HPA043056, HPA045090, HPA049080" Supported Approved Vesicles NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 37: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 102: Non-specific - Mixed function" Vesicles "HPA042121: , HPA043056: , HPA045090: , HPA049080: " "unprognostic (1.62e-2)" "unprognostic (1.77e-1)" "unprognostic (9.87e-3)" "unprognostic (1.82e-1)" "unprognostic (6.69e-2)" "unprognostic (1.52e-3)" "unprognostic (2.73e-1)" LRRC37A3 "FLJ34306, KIAA0563" ENSG00000176809 "Leucine rich repeat containing 37 member A3" O60309 17 64854130-64919480 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 27.9" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 143.1;Ependymal cells: 110.1;Loop of henle epithelial cells: 155.1;Papillary tip epithelial cells: 142.8;Proximal tubule cells: 141.5;Renal collecting duct intercalated cells: 120.3;Renal collecting duct principal cells: 184.7;Renal connecting tubule cells: 125.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Testis - Early spermatids, Testis - Late spermatids" "HPA042121, HPA043056, HPA045090" Supported Approved Vesicles NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 72: Kidney - Transmembrane transport" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 105: Non-specific - Mixed function" Vesicles "HPA042121: , HPA043056: , HPA045090: " "unprognostic (2.32e-2)" "unprognostic (1.53e-1)" "unprognostic (9.63e-2)" "unprognostic (4.75e-2)" "unprognostic (1.06e-1)" "unprognostic (1.67e-1)" "unprognostic (5.75e-2)" "unprognostic (1.64e-1)" "unprognostic (2.01e-1)" "unprognostic (1.13e-3)" "unprognostic (3.63e-2)" "unprognostic (2.65e-1)" "unprognostic (1.42e-1)" "unprognostic (4.38e-2)" "unprognostic (2.79e-1)" "unprognostic (2.29e-2)" "unprognostic (3.51e-1)" "unprognostic (8.83e-2)" "unprognostic (1.35e-1)" "unprognostic (1.65e-1)" "unprognostic (5.10e-2)" "potential prognostic favorable (1.94e-4)" "unprognostic (5.22e-3)" "unprognostic (2.38e-1)" "unprognostic (4.36e-2)" "potential prognostic favorable (3.05e-4)" "unprognostic (1.27e-1)" "unprognostic (2.14e-1)" "unprognostic (1.00e-1)" "unprognostic (1.49e-1)" "unprognostic (1.59e-2)" LRRC37B ENSG00000185158 "Leucine rich repeat containing 37B" Q96QE4 17 32007383-32053504 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 110.0;Gonadotrophs: 80.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "granulocytes: 2.0;NK-cells: 5.2;T-cells: 3.0" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" HPA015135 Approved Approved Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 27: Cerebellum - Synaptic function" "Cluster 15: Non-specific - Transcription" "Cluster 59: Leukemia - T-cell receptor" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" Cytosol "HPA015135: " "potential prognostic unfavorable (8.08e-4)" "unprognostic (1.12e-2)" "unprognostic (9.73e-3)" "unprognostic (4.68e-2)" "unprognostic (4.34e-2)" "unprognostic (4.01e-2)" "unprognostic (1.08e-1)" "potential prognostic favorable (9.67e-4)" "unprognostic (1.20e-2)" "unprognostic (2.19e-3)" "unprognostic (1.84e-2)" "unprognostic (2.97e-1)" "unprognostic (1.43e-1)" "unprognostic (1.66e-2)" "unprognostic (8.88e-2)" "unprognostic (6.88e-2)" "unprognostic (1.52e-1)" "unprognostic (3.84e-2)" "unprognostic (2.30e-1)" "unprognostic (3.45e-3)" "unprognostic (2.39e-1)" "unprognostic (7.12e-2)" "unprognostic (1.25e-3)" "unprognostic (1.81e-1)" "unprognostic (1.27e-1)" "unprognostic (2.30e-3)" "unprognostic (2.28e-1)" "unprognostic (2.89e-1)" "unprognostic (3.31e-1)" "unprognostic (1.45e-1)" "unprognostic (4.57e-2)" LRRC38 ENSG00000162494 "Leucine rich repeat containing 38" Q5VT99 1 13474973-13514003 "Predicted membrane proteins" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "adrenal gland: 19.7;skeletal muscle: 44.7;tongue: 13.7" "Group enriched" "Detected in some" 4 "Adrenal cortex cells: 46.7;Myonuclei: 117.0;Oocytes: 87.5;Retinal bipolar cells: 34.3" "Cell type enhanced" "Detected in some" "cerebellar inhibitory: 70.6;fibroblast: 21.9" "Cancer enhanced" "Detected in single" "Lung Adenocarcinoma (TCGA): 1.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "thyroid cancer: 6.9" "Adipose visceral - Mesothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA038778 Approved NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 2: Neurons - Nucleosome" "Cluster 59: Leukemia - T-cell receptor" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" "HPA038778: " "unprognostic (8.53e-2)" LRRC39 "MGC14816, myomasp" ENSG00000122477 "Leucine rich repeat containing 39" Q96DD0 1 100148448-100178273 "Predicted intracellular proteins" "Muscle protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 100.1;retina: 109.2;skeletal muscle: 403.8;tongue: 161.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 150.0;Cone photoreceptor cells: 302.2;Hofbauer cells: 246.8;Late primary spermatocytes: 281.5;Myonuclei: 784.4;Retinal amacrine cells: 90.3;Retinal horizontal cells: 138.2;Rod photoreceptor cells: 356.6" "Cell type enhanced" "Detected in all" "CGE interneuron: 119.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA077159 Enhanced NA NA "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 56: Non-specific - Sensory perception" "Cluster 55: Myocytes - Oxidative muscle function" 1 "HPA077159: " "unprognostic (6.53e-2)" "unprognostic (3.92e-2)" "unprognostic (1.60e-2)" "unprognostic (4.92e-2)" "unprognostic (3.06e-2)" "unprognostic (2.47e-1)" "unprognostic (7.27e-2)" "unprognostic (3.06e-3)" "unprognostic (2.35e-1)" "unprognostic (3.39e-2)" "unprognostic (2.65e-1)" "unprognostic (3.22e-2)" "unprognostic (4.91e-2)" "unprognostic (3.77e-3)" "unprognostic (5.57e-2)" "unprognostic (4.26e-2)" "unprognostic (3.12e-1)" "unprognostic (2.40e-2)" "unprognostic (2.97e-2)" LRRC3B LRP15 ENSG00000179796 "Leucine rich repeat containing 3B" Q96PB8 3 26622772-26717537 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 23.8;skeletal muscle: 8.8;testis: 6.7" "Cell type enhanced" "Detected in some" "Astrocytes: 443.4;Bergmann glia: 75.5;Brain excitatory neurons: 140.0;Brain inhibitory neurons: 61.5;Early spermatids: 69.0;Ependymal cells: 163.0;Late primary spermatocytes: 133.0;Medullary thymic epithelial cells: 112.8;Oligodendrocyte progenitor cells: 52.6;Other brain neurons: 97.3;Pituitary stem cells: 90.8" "Cell type enhanced" "Detected in all" "astrocyte: 382.8;upper rhombic lip: 346.1" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 8.4;Ovary Serous Cystadenocarcinoma (TCGA): 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "testis cancer: 2.4" "Pituitary gland - Undifferentiated cells (Pituitary gland), Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA015568 Approved NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 15: Non-specific - Transcription" "Cluster 6: Leukemia - Signal transduction" "Cluster 28: Astrocytes - Homeostasis & neuron support" 9 "HPA015568: " "unprognostic (1.20e-1)" "unprognostic (2.94e-1)" "unprognostic (3.48e-3)" "unprognostic (9.73e-2)" "unprognostic (9.57e-2)" "unprognostic (5.68e-1)" LRRC3C ENSG00000204913 "Leucine rich repeat containing 3C" A6NJW4 17 39927732-39944999 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "epididymis: 1.0" "Cell type enhanced" "Detected in some" "Early spermatids: 7.4;Epididymal principal cells: 4.8;Hepatocytes: 1.7;Late primary spermatocytes: 5.8;Late spermatids: 4.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA071271 Uncertain NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" "HPA071271: " LRRC4 NAG14 ENSG00000128594 "Leucine rich repeat containing 4" Q9HBW1 7 128027071-128032107 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 46.7;Kupffer cells: 31.8;Neutrophils: 72.2;Ocular epithelial cells: 47.6;Respiratory ciliated cells: 74.3;Retinal horizontal cells: 32.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "neutrophil: 13.1" "Lineage enriched" "Detected in single" 20 "granulocytes: 13.1" "Cancer enhanced" "Detected in many" "Neuroblastoma: 8.2" "Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051100 Supported "Golgi apparatus" NA NA 730000 "Cluster 4: Neutrophils - Degranulation" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 4 "Golgi apparatus" "HPA051100: " "unprognostic (1.06e-2)" "unprognostic (2.31e-2)" "unprognostic (8.74e-3)" "unprognostic (8.31e-3)" "unprognostic (1.42e-1)" "unprognostic (3.61e-2)" "potential prognostic favorable (8.88e-6)" "unprognostic (4.33e-3)" "unprognostic (3.92e-2)" "potential prognostic favorable (4.88e-7)" "unprognostic (6.15e-3)" "unprognostic (5.03e-2)" "unprognostic (2.88e-1)" "unprognostic (8.99e-3)" "potential prognostic favorable (6.17e-4)" "unprognostic (3.74e-1)" "unprognostic (9.54e-3)" "potential prognostic favorable (2.62e-4)" "potential prognostic favorable (6.15e-4)" "unprognostic (8.13e-2)" "unprognostic (6.67e-2)" "unprognostic (1.82e-1)" "unprognostic (2.18e-1)" "unprognostic (1.28e-2)" LRRC40 FLJ20331 ENSG00000066557 "Leucine rich repeat containing 40" Q9H9A6 1 70144805-70205579 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA026564 Approved Approved Nucleoli NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 7: Non-specific - Transcription" 9 Nucleoli "HPA026564: " "unprognostic (5.28e-2)" "unprognostic (2.86e-1)" "unprognostic (1.11e-1)" "unprognostic (6.15e-3)" "potential prognostic favorable (3.35e-4)" "unprognostic (1.97e-2)" "unprognostic (2.17e-2)" "unprognostic (1.72e-2)" "unprognostic (7.66e-2)" "unprognostic (1.86e-3)" "potential prognostic favorable (6.40e-5)" "unprognostic (1.35e-1)" "unprognostic (7.21e-2)" "unprognostic (1.36e-3)" "unprognostic (4.23e-1)" "unprognostic (2.92e-2)" "unprognostic (2.92e-3)" "unprognostic (1.14e-1)" "unprognostic (6.79e-2)" "unprognostic (1.82e-1)" "unprognostic (2.59e-3)" "unprognostic (7.88e-3)" "unprognostic (2.80e-2)" "unprognostic (6.09e-3)" "unprognostic (7.14e-2)" "unprognostic (1.95e-1)" "unprognostic (4.84e-2)" "unprognostic (9.73e-2)" "unprognostic (1.89e-1)" "unprognostic (1.91e-2)" "unprognostic (1.71e-1)" LRRC41 MUF1 ENSG00000132128 "Leucine rich repeat containing 41" Q15345 1 46261196-46303616 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial glandular cells: 515.9;Endometrial luminal cells: 986.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051941 Uncertain Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 75: Ovary - Mixed function" "Cluster 27: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 17 "Nuclear bodies" Nucleoplasm "HPA051941: " "unprognostic (5.20e-2)" "unprognostic (2.29e-2)" "unprognostic (9.61e-3)" "unprognostic (1.02e-2)" "unprognostic (2.58e-3)" "unprognostic (2.71e-1)" "unprognostic (1.66e-1)" "unprognostic (1.92e-3)" "unprognostic (2.84e-2)" "unprognostic (2.09e-1)" "unprognostic (8.91e-3)" "unprognostic (1.08e-1)" "unprognostic (4.09e-1)" "potential prognostic unfavorable (4.56e-8)" "unprognostic (7.47e-3)" "unprognostic (1.17e-1)" "unprognostic (4.48e-3)" "unprognostic (2.81e-1)" "unprognostic (1.92e-1)" "unprognostic (1.72e-1)" "unprognostic (4.68e-2)" "unprognostic (2.83e-1)" "unprognostic (5.91e-2)" "unprognostic (3.99e-1)" "unprognostic (5.81e-2)" "unprognostic (3.39e-2)" "unprognostic (5.20e-2)" "unprognostic (2.14e-2)" "unprognostic (4.75e-1)" "unprognostic (1.21e-1)" "unprognostic (1.81e-1)" LRRC42 MGC8974 ENSG00000116212 "Leucine rich repeat containing 42" Q9Y546 1 53946085-53968168 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047458, HPA050537, HPA064581" Uncertain Enhanced Nucleoplasm NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 28: Liver & Adrenal gland - Secretion" "Cluster 21: Non-specific - Metabolism" "Cluster 37: Non-specific - mRNA processing" "Cluster 26: Keratinocytes - Keratinization" 2 Nucleoplasm "HPA047458: , HPA050537: , HPA064581: " "unprognostic (1.78e-1)" "unprognostic (2.43e-1)" "unprognostic (2.50e-1)" "unprognostic (1.51e-1)" "unprognostic (5.69e-3)" "unprognostic (1.86e-1)" "unprognostic (6.40e-3)" "unprognostic (1.56e-2)" "unprognostic (3.28e-2)" "unprognostic (6.88e-3)" "potential prognostic favorable (8.29e-4)" "unprognostic (2.68e-1)" "unprognostic (5.33e-2)" "potential prognostic unfavorable (1.58e-6)" "unprognostic (1.31e-1)" "unprognostic (1.18e-3)" "unprognostic (5.09e-3)" "unprognostic (2.35e-1)" "unprognostic (2.33e-1)" "unprognostic (7.91e-2)" "unprognostic (3.01e-1)" "unprognostic (9.63e-3)" "unprognostic (1.17e-1)" "unprognostic (3.70e-1)" "unprognostic (4.16e-1)" "unprognostic (6.00e-2)" "unprognostic (9.33e-2)" "unprognostic (9.32e-3)" "unprognostic (1.48e-1)" "unprognostic (2.87e-3)" "unprognostic (3.23e-1)" LRRC43 MGC35140 ENSG00000158113 "Leucine rich repeat containing 43" Q8N309 12 122167738-122203471 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 10.2;fallopian tube: 17.9" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 25.7;Cone photoreceptor cells: 37.3;Early spermatids: 23.0;Endometrial ciliated cells: 47.1;Ependymal cells: 36.8;Epididymal efferent duct ciliated cells: 51.6;Fallopian tube ciliated cells: 89.6;Late primary spermatocytes: 26.1;Late spermatids: 64.3;Paneth cells: 27.1;Respiratory ciliated cells: 101.3" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 21.1;ependymal cell: 39.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA039425 Approved "Golgi apparatus,Vesicles" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" "Golgi apparatus" Vesicles "HPA039425: " "unprognostic (2.53e-2)" "unprognostic (8.43e-3)" "unprognostic (1.77e-3)" "unprognostic (3.91e-2)" "unprognostic (3.38e-3)" "potential prognostic favorable (6.86e-5)" "unprognostic (8.29e-3)" "unprognostic (2.16e-1)" "unprognostic (6.52e-2)" "unprognostic (1.64e-1)" "unprognostic (2.94e-1)" "unprognostic (4.76e-2)" "unprognostic (1.20e-3)" "unprognostic (2.66e-1)" "unprognostic (2.97e-2)" "unprognostic (3.63e-2)" LRRC45 MGC20806 ENSG00000169683 "Leucine rich repeat containing 45" Q96CN5 17 82023305-82031151 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 40.6;Fallopian tube ciliated cells: 49.0;Respiratory ciliated cells: 66.3" "Cell type enhanced" "Detected in many" "ependymal cell: 20.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023372, HPA023382, HPA024768" Enhanced Approved "Plasma membrane,Centrosome,Basal body,Cytosol,Mid piece,Principal piece" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 64: Non-specific - Transcription" "Cluster 2: Neurons - Nucleosome" "Cluster 27: Breast cancer - Unknown function" "Cluster 107: Ciliated cells - Cilia assembly & function" 6 "Centrosome, Basal body, Cytosol" "Plasma membrane, Mid piece, Principal piece" "HPA023372: , HPA023382: , HPA024768: " "unprognostic (6.67e-2)" "unprognostic (2.00e-1)" "unprognostic (9.75e-2)" "unprognostic (3.28e-2)" "unprognostic (2.07e-1)" "unprognostic (6.88e-2)" "unprognostic (1.56e-1)" "unprognostic (3.47e-2)" "unprognostic (4.49e-2)" "unprognostic (5.93e-2)" "unprognostic (6.00e-2)" "unprognostic (7.51e-2)" "unprognostic (2.71e-1)" "unprognostic (1.26e-2)" "unprognostic (1.16e-3)" "unprognostic (3.51e-2)" "unprognostic (1.88e-2)" "unprognostic (8.70e-2)" "unprognostic (8.36e-2)" "unprognostic (5.02e-3)" "potential prognostic favorable (8.78e-5)" "unprognostic (5.51e-3)" "unprognostic (3.24e-1)" "unprognostic (7.04e-2)" "unprognostic (1.27e-2)" "unprognostic (2.30e-1)" "unprognostic (1.67e-1)" "unprognostic (6.71e-3)" "unprognostic (2.61e-1)" "potential prognostic unfavorable (4.48e-4)" "unprognostic (4.85e-1)" LRRC46 MGC16309 ENSG00000141294 "Leucine rich repeat containing 46" Q96FV0 17 47831634-47837719 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 73.8;testis: 49.1" "Cell type enhanced" "Detected in some" "Early spermatids: 126.8;Endometrial ciliated cells: 171.1;Ependymal cells: 87.6;Epididymal efferent duct ciliated cells: 183.8;Fallopian tube ciliated cells: 392.7;Late primary spermatocytes: 305.5;Late spermatids: 85.5;Respiratory ciliated cells: 318.3" "Cell type enriched" "Detected in some" 9 "ependymal cell: 107.0" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 14.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in single" "Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA074893 Enhanced Approved "Nuclear bodies,Plasma membrane,Primary cilium,Basal body" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" 4 "Plasma membrane" "Nuclear bodies, Primary cilium, Basal body" "HPA074893: " "unprognostic (1.91e-1)" "unprognostic (2.45e-1)" "potential prognostic favorable (5.86e-4)" "unprognostic (5.47e-3)" "unprognostic (6.66e-2)" "unprognostic (1.16e-2)" "unprognostic (1.44e-1)" "unprognostic (4.80e-2)" "unprognostic (2.06e-1)" "unprognostic (1.93e-1)" "unprognostic (2.58e-1)" "unprognostic (9.39e-2)" "unprognostic (1.61e-2)" "unprognostic (3.74e-1)" "unprognostic (3.09e-1)" "unprognostic (1.53e-1)" LRRC47 "KIAA1185, RP1-286D6.3" ENSG00000130764 "Leucine rich repeat containing 47" Q8N1G4 1 3778559-3796498 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008512, HPA012018" Enhanced Approved "Nucleoli fibrillar center" NA NA 14000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 24: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 37: Non-specific - mRNA processing" "Cluster 97: Non-specific - Cellular respiration" 8 "Nucleoli fibrillar center" "HPA008512: , HPA012018: " "unprognostic (1.48e-1)" "unprognostic (2.17e-1)" "unprognostic (4.23e-3)" "unprognostic (2.99e-2)" "unprognostic (9.62e-2)" "unprognostic (3.32e-1)" "unprognostic (1.93e-1)" "unprognostic (2.17e-2)" "unprognostic (1.36e-1)" "unprognostic (1.16e-2)" "potential prognostic favorable (4.42e-6)" "unprognostic (3.25e-3)" "unprognostic (3.29e-3)" "validated prognostic unfavorable (2.96e-4)" "validated prognostic unfavorable (6.41e-5)" "unprognostic (1.37e-1)" "unprognostic (1.14e-1)" "unprognostic (3.11e-1)" "unprognostic (2.92e-1)" "unprognostic (1.39e-1)" "unprognostic (9.67e-2)" "unprognostic (2.65e-2)" "unprognostic (1.08e-1)" "unprognostic (6.99e-2)" "unprognostic (2.57e-1)" "potential prognostic favorable (1.68e-5)" "unprognostic (7.52e-2)" "unprognostic (2.20e-1)" "unprognostic (1.15e-1)" "unprognostic (1.06e-2)" "unprognostic (2.11e-1)" LRRC49 "CSTPP2, FLJ20156, PGs4" ENSG00000137821 "Leucine rich repeat containing 49" Q8IUZ0 15 70853239-71053658 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 28.0;heart muscle: 52.7" "Cell type enhanced" "Detected in many" "Ependymal cells: 187.2;Lactotrophs: 236.1;Late spermatids: 175.8;Retinal bipolar cells: 248.6;Somatotrophs: 213.0;Thyrotrophs: 298.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015596 Uncertain NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 11 "HPA015596: " "unprognostic (6.03e-2)" "unprognostic (3.48e-1)" "unprognostic (1.75e-1)" "unprognostic (8.62e-3)" "unprognostic (4.69e-2)" "unprognostic (9.86e-2)" "unprognostic (4.06e-1)" "potential prognostic favorable (6.33e-4)" "unprognostic (8.24e-3)" "unprognostic (1.44e-1)" "unprognostic (3.58e-2)" "potential prognostic favorable (5.11e-4)" "unprognostic (1.38e-1)" "unprognostic (1.96e-1)" "unprognostic (2.53e-1)" "unprognostic (2.89e-1)" "unprognostic (1.34e-1)" "unprognostic (2.57e-1)" "unprognostic (2.14e-1)" "unprognostic (2.23e-3)" "unprognostic (8.96e-2)" "unprognostic (4.25e-1)" "unprognostic (1.40e-1)" "unprognostic (2.50e-1)" "unprognostic (4.63e-2)" "unprognostic (8.93e-2)" "unprognostic (4.31e-2)" "unprognostic (1.72e-1)" LRRC4B "DKFZp761A179, HSM, LRIG4" ENSG00000131409 "Leucine rich repeat containing 4B" Q9NT99 19 50516892-50568435 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 99.9;cervix: 35.5" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 42.5;Astrocytes: 54.1;Bergmann glia: 34.6;Brain excitatory neurons: 63.0;Brain inhibitory neurons: 76.3;Corticotrophs: 32.3;Ependymal cells: 69.1;Lactotrophs: 50.5;Oligodendrocyte progenitor cells: 77.3;Oligodendrocytes: 69.0;Other brain neurons: 64.3;Retinal amacrine cells: 61.6;Retinal bipolar cells: 32.1;Somatotrophs: 32.5;Thyrotrophs: 32.2" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" 8 "Glioblastoma Multiforme (TCGA): 64.3;Testicular Germ Cell Tumor (TCGA): 16.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Bone cancer: 14.6;Neuroblastoma: 25.7;Rhabdoid: 21.3;skin cancer: 6.7" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal medulla cells, Liver - Hepatic stellate cells, Skeletal muscle - Smooth muscle cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058986 Uncertain NA NA 1100000 "Cluster 3: Oligodendrocytes - Myelination" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" "HPA058986: " "unprognostic (3.03e-1)" "unprognostic (8.70e-3)" "unprognostic (7.38e-2)" "unprognostic (2.66e-1)" "unprognostic (1.04e-1)" "unprognostic (3.28e-2)" "potential prognostic favorable (2.60e-4)" "potential prognostic unfavorable (8.10e-4)" "unprognostic (1.49e-1)" "unprognostic (4.80e-3)" "unprognostic (1.15e-1)" "unprognostic (1.48e-2)" "potential prognostic favorable (5.33e-4)" "unprognostic (7.90e-2)" "unprognostic (1.23e-2)" "unprognostic (1.29e-1)" "unprognostic (1.34e-2)" "unprognostic (1.51e-1)" "unprognostic (1.10e-1)" LRRC4C "KIAA1580, NGL-1" ENSG00000148948 "Leucine rich repeat containing 4C" Q9HCJ2 11 40114203-41459773 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 19.4;retina: 15.8" "Cell type enhanced" "Detected in many" "Astrocytes: 904.8;Bergmann glia: 715.0;Brain excitatory neurons: 1207.0;Brain inhibitory neurons: 2018.2;Müller glia: 1730.1;Oligodendrocyte progenitor cells: 7307.0;Other brain neurons: 1649.3;Retinal amacrine cells: 2107.2;Retinal ganglion cells: 1143.4;Thyrotrophs: 2000.4" "Cell type enhanced" "Detected in all" "oligodendrocyte precursor cell: 8620.3" "Group enriched" "Detected in some" 4 "Breast Invasive Carcinoma (TCGA): 3.3;Glioblastoma Multiforme (TCGA): 11.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 7.9" "Colon - Enteric glia cells, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054800, HPA075816" Supported Approved Cytosol NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 23 Cytosol "HPA054800: , HPA075816: " "unprognostic (7.22e-3)" "unprognostic (2.27e-1)" "unprognostic (1.65e-1)" "unprognostic (1.78e-3)" "unprognostic (2.82e-2)" "unprognostic (4.53e-2)" "unprognostic (2.37e-1)" "unprognostic (1.47e-1)" "unprognostic (3.12e-1)" "unprognostic (1.15e-1)" "unprognostic (4.52e-2)" "unprognostic (1.58e-1)" LRRC51 ENSG00000184154 "Leucine rich repeat containing 51" Q96E66 11 72080337-72096895 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "fallopian tube: 63.4;testis: 93.1" "Cell type enriched" "Detected in many" 6 "Late spermatids: 3297.4" "Cell type enriched" "Detected in single" 7 "ependymal cell: 5.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039949 Approved Uncertain Microtubules NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" Microtubules "HPA039949: " "unprognostic (9.66e-2)" "unprognostic (2.54e-1)" "unprognostic (2.17e-1)" "unprognostic (7.77e-2)" "unprognostic (3.10e-1)" "unprognostic (9.40e-2)" "unprognostic (1.17e-1)" "unprognostic (7.68e-2)" "unprognostic (1.31e-1)" "potential prognostic unfavorable (4.63e-4)" "validated prognostic favorable (6.53e-4)" "validated prognostic favorable (6.81e-4)" "unprognostic (2.28e-3)" "unprognostic (2.97e-2)" "unprognostic (5.15e-3)" "unprognostic (2.07e-1)" "unprognostic (1.20e-1)" "unprognostic (7.91e-2)" "unprognostic (5.53e-2)" "unprognostic (7.98e-3)" "unprognostic (1.02e-1)" "unprognostic (3.22e-1)" "unprognostic (2.79e-1)" "unprognostic (4.34e-2)" "unprognostic (7.54e-2)" "unprognostic (1.81e-1)" "unprognostic (2.06e-2)" "unprognostic (1.51e-1)" "unprognostic (1.94e-2)" "unprognostic (1.72e-1)" "unprognostic (2.54e-1)" LRRC52 FLJ25811 ENSG00000162763 "Leucine rich repeat containing 52" Q8N7C0 1 165544000-165563957 "Predicted membrane proteins" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "testis: 15.6" "Cell type enhanced" "Detected in some" "Early spermatids: 235.3;Late primary spermatocytes: 96.0;Late spermatids: 43.4;Retinal ganglion cells: 15.5" "Cell type enhanced" "Detected in single" "choroid plexus epithelial cell: 1.7" "Cancer enhanced" "Detected in single" "Kidney Chromophobe (TCGA): 1.7" "Region enhanced" "Detected in single" "choroid plexus: 2.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" "unprognostic (2.10e-2)" LRRC53 ENSG00000162621 "Leucine rich repeat containing 53" A6NM62 1 74469376-74512611 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 60 "Cardiomyocytes: 771.9" "Group enriched" "Detected in many" 4 "amygdala excitatory: 5.9;deep-layer intratelencephalic: 5.4;hippocampal dentate gyrus: 20.7;upper-layer intratelencephalic: 16.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Rhabdoid: 1.2" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" HPA054062 Uncertain NA NA "Cluster 53: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" "HPA054062: " LRRC55 FLJ45686 ENSG00000183908 "Leucine rich repeat containing 55" Q6ZSA7 11 57181747-57191717 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.7;lymphoid tissue: 1.9" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 2.4;Brain inhibitory neurons: 3.2;Endometrial secretory cells: 1.9;Fallopian secretory cells: 1.4;Other brain neurons: 6.0;Podocytes: 1.0" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in some" 4 "Glioblastoma Multiforme (TCGA): 14.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Neuroblastoma: 3.1" "Colon - Colon enteroendocrine cells" "Region enhanced" "Detected in all" "olfactory bulb: 105.4" "Low region specificity" "Detected in all" HPA014053 Uncertain NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 44: Non-specific - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" "HPA014053: " "unprognostic (1.18e-1)" "potential prognostic favorable (5.32e-4)" "unprognostic (1.77e-2)" "unprognostic (2.85e-1)" "unprognostic (2.71e-1)" "unprognostic (1.56e-1)" LRRC56 "DKFZp761L1518, DNAAF12, FLJ00101" ENSG00000161328 "Leucine rich repeat containing 56" Q8IYG6 11 537527-554912 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 11.8;testis: 21.3" "Cell type enhanced" "Detected in some" "Early spermatids: 35.8;Ependymal cells: 12.6;Epididymal efferent duct ciliated cells: 17.2;Late primary spermatocytes: 25.9;Late spermatids: 111.7;Respiratory ciliated cells: 10.1;Tuft cells: 11.5" "Cell type enhanced" "Detected in many" "ependymal cell: 14.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 2.4" "Breast - Breast glandular cells, Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Spleen - B-cells (Spleen), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA038728 Approved NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 33: Neurons - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 10 "HPA038728: " "unprognostic (5.74e-2)" "unprognostic (3.46e-1)" "unprognostic (2.64e-1)" "unprognostic (2.82e-1)" "unprognostic (1.77e-2)" "unprognostic (3.21e-2)" "unprognostic (9.77e-2)" "unprognostic (1.11e-1)" "unprognostic (5.15e-2)" "unprognostic (1.71e-2)" "unprognostic (2.73e-2)" "unprognostic (4.21e-1)" "unprognostic (7.53e-2)" "unprognostic (1.35e-1)" LRRC57 FLJ36812 ENSG00000180979 "Leucine rich repeat containing 57" Q8N9N7 15 42537820-42548802 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 6.4;Early spermatids: 7.7;Late spermatids: 12.1;Loop of henle epithelial cells: 7.6;Megakaryocytes: 6.2;Papillary tip epithelial cells: 10.2;Podocytes: 11.4;Renal collecting duct intercalated cells: 8.2;Renal collecting duct principal cells: 8.8;Renal connecting tubule cells: 6.8;Tuft cells: 11.5" "Cell type enhanced" "Detected in some" "hippocampal dentate gyrus: 2.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040894 Approved Approved Mitochondria,Cytosol NA NA 12000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 40: Non-specific - Mixed function" "Cluster 34: Non-specific - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 105: Non-specific - Mixed function" 4 "Mitochondria, Cytosol" "HPA040894: " "unprognostic (3.03e-2)" "unprognostic (7.08e-3)" "unprognostic (6.67e-2)" "unprognostic (4.07e-1)" "unprognostic (2.02e-1)" "unprognostic (2.30e-2)" "unprognostic (1.14e-1)" "unprognostic (5.22e-2)" "unprognostic (2.35e-1)" "unprognostic (1.16e-1)" "potential prognostic favorable (6.70e-5)" "unprognostic (1.17e-3)" "unprognostic (3.18e-1)" "unprognostic (1.37e-2)" "unprognostic (4.18e-3)" "unprognostic (1.26e-1)" "unprognostic (1.77e-1)" "unprognostic (7.58e-2)" "unprognostic (2.73e-1)" "unprognostic (2.21e-2)" "unprognostic (3.05e-1)" "unprognostic (8.20e-3)" "unprognostic (1.65e-2)" "unprognostic (4.65e-2)" "unprognostic (2.58e-2)" "unprognostic (1.69e-2)" "unprognostic (5.49e-2)" "unprognostic (1.44e-1)" "unprognostic (4.07e-2)" "unprognostic (3.90e-1)" "unprognostic (5.07e-2)" LRRC58 ENSG00000163428 "Leucine rich repeat containing 58" Q96CX6 3 120324509-120349354 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adrenal cortex cells: 168.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057574 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 18: Adrenal cortex cells - Steroidogensis" 2 Nucleoplasm Cytosol "HPA057574: " "unprognostic (5.34e-3)" "unprognostic (1.95e-2)" "unprognostic (1.71e-1)" "unprognostic (3.48e-2)" "unprognostic (1.15e-1)" "unprognostic (1.17e-1)" "unprognostic (1.30e-1)" "unprognostic (2.52e-1)" "unprognostic (7.21e-2)" "unprognostic (3.12e-3)" "potential prognostic favorable (2.99e-5)" "unprognostic (8.06e-2)" "unprognostic (6.73e-2)" "validated prognostic unfavorable (5.13e-4)" "validated prognostic unfavorable (6.44e-4)" "potential prognostic unfavorable (6.82e-4)" "unprognostic (9.71e-2)" "unprognostic (9.92e-2)" "unprognostic (7.04e-2)" "unprognostic (6.61e-2)" "unprognostic (1.03e-1)" "unprognostic (2.11e-2)" "unprognostic (1.12e-1)" "unprognostic (1.93e-1)" "unprognostic (1.05e-1)" "unprognostic (4.27e-1)" "unprognostic (1.27e-2)" "unprognostic (6.32e-2)" "unprognostic (1.23e-1)" "unprognostic (5.87e-3)" "unprognostic (1.25e-1)" LRRC59 "FLJ21675, PRO1855" ENSG00000108829 "Leucine rich repeat containing 59" Q96AG4 17 50375059-50397523 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 356.4;Syncytiotrophoblasts: 293.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Mitotic cells (Spleen), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030827, HPA030829" Enhanced Enhanced "Endoplasmic reticulum" NA NA 4000000 "Cluster 29: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 27: Breast cancer - Unknown function" "Cluster 8: Non-specific - Secretory pathway" 122 "Endoplasmic reticulum" "HPA030827: , HPA030829: " "unprognostic (8.86e-2)" "unprognostic (7.75e-3)" "unprognostic (1.08e-1)" "unprognostic (1.06e-2)" "unprognostic (3.09e-3)" "unprognostic (3.72e-1)" "unprognostic (2.10e-1)" "unprognostic (4.91e-2)" "potential prognostic unfavorable (8.10e-5)" "unprognostic (7.35e-3)" "unprognostic (1.28e-3)" "unprognostic (2.77e-2)" "unprognostic (3.76e-3)" "validated prognostic unfavorable (1.27e-5)" "validated prognostic unfavorable (1.25e-9)" "unprognostic (2.45e-3)" "potential prognostic unfavorable (7.97e-5)" "unprognostic (1.33e-1)" "unprognostic (9.84e-2)" "unprognostic (7.83e-2)" "unprognostic (2.74e-1)" "unprognostic (1.42e-3)" "unprognostic (1.37e-1)" "unprognostic (4.68e-2)" "unprognostic (1.27e-1)" "unprognostic (3.63e-2)" "unprognostic (1.45e-1)" "unprognostic (1.52e-1)" "unprognostic (8.49e-2)" "unprognostic (1.01e-3)" "unprognostic (9.64e-2)" LRRC61 "FLJ31392, HSPC295, MGC3036" ENSG00000127399 "Leucine rich repeat containing 61" Q9BV99 7 150323263-150338156 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 5.2;Epicardial cells: 4.5;Fallopian tube ciliated cells: 5.3;Loop of henle epithelial cells: 13.0;Papillary tip epithelial cells: 9.1;Podocytes: 6.7;Proximal tubule cells: 6.9;Renal collecting duct intercalated cells: 11.8;Renal collecting duct principal cells: 14.0;Renal connecting tubule cells: 7.0" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019355 Approved Approved Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 70: Non-specific - Protein processing" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 14 Nucleoplasm "HPA019355: " "unprognostic (8.57e-2)" "unprognostic (1.74e-1)" "unprognostic (1.40e-1)" "unprognostic (1.75e-1)" "unprognostic (4.55e-2)" "unprognostic (7.10e-2)" "potential prognostic unfavorable (1.13e-5)" "unprognostic (1.17e-2)" "unprognostic (6.02e-3)" "unprognostic (9.69e-2)" "unprognostic (1.15e-2)" "unprognostic (1.94e-1)" "unprognostic (1.33e-1)" "unprognostic (3.38e-3)" "unprognostic (5.82e-3)" "potential prognostic unfavorable (5.70e-4)" "unprognostic (3.84e-2)" "unprognostic (4.44e-3)" "unprognostic (6.77e-2)" "unprognostic (7.99e-2)" "unprognostic (1.80e-1)" "unprognostic (1.69e-2)" "unprognostic (3.16e-3)" "unprognostic (3.20e-1)" "unprognostic (2.61e-1)" "unprognostic (3.82e-2)" "unprognostic (4.25e-2)" "potential prognostic favorable (5.31e-4)" "unprognostic (7.47e-2)" "unprognostic (6.04e-2)" "unprognostic (5.95e-2)" LRRC63 RP11-139H14.4 ENSG00000173988 "Leucine rich repeat containing 63" 13 46211928-46277115 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 9.9;testis: 3.2" "Cell type enhanced" "Detected in many" "Early spermatids: 129.6;Ependymal cells: 96.4;Epididymal principal cells: 34.6;Fallopian tube ciliated cells: 47.6;Hematopoietic stem cells: 31.5;Late primary spermatocytes: 75.6;Late spermatids: 40.3;Oligodendrocytes: 202.8;Respiratory ciliated cells: 73.2;Rod photoreceptor cells: 38.8" "Group enriched" "Detected in many" 4 "ependymal cell: 95.8;oligodendrocyte: 366.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA039318, HPA039763" Uncertain Approved "Golgi apparatus" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 80: Oligodendrocytes - Myelination" "Golgi apparatus" "HPA039318: , HPA039763: " "unprognostic (3.41e-1)" LRRC66 ENSG00000188993 "Leucine rich repeat containing 66" Q68CR7 4 51993652-52020363 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 20.8;skeletal muscle: 7.4" "Cell type enhanced" "Detected in many" "Colonocytes: 17.2;Corticotrophs: 17.9;Enterocytes: 52.3;Foveolar cells: 16.7;Myonuclei: 61.5;Pituicytes/FSCs: 16.8;Podocytes: 32.5;Thymic myoid cells: 23.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Pancreatic Adenocarcinoma (TCGA): 3.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 1.4" "Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA014549, HPA027839" Uncertain NA NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 37: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" "HPA014549: , HPA027839: " "unprognostic (1.56e-2)" "unprognostic (1.00e-1)" "unprognostic (2.20e-1)" "unprognostic (8.05e-2)" "unprognostic (1.77e-2)" "unprognostic (4.37e-3)" "unprognostic (4.67e-2)" "unprognostic (2.31e-2)" "unprognostic (1.23e-3)" "unprognostic (1.96e-1)" "unprognostic (5.49e-2)" "unprognostic (2.37e-1)" LRRC69 ENSG00000214954 "Leucine rich repeat containing 69" Q6ZNQ3 8 91101832-91219257 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 2.7" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 68.9;Late primary spermatocytes: 100.7;Microglia: 63.1" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 81.7" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 3.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 7.3" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA046337 Uncertain Approved "Plasma membrane" NA NA "Cluster 47: Testis - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 20: Myeloma - Immune response" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" "Plasma membrane" "HPA046337: " "unprognostic (9.95e-2)" "unprognostic (1.02e-1)" "unprognostic (1.35e-1)" "unprognostic (1.77e-1)" "unprognostic (8.16e-2)" "unprognostic (1.69e-1)" "unprognostic (7.66e-2)" "unprognostic (1.88e-1)" "unprognostic (7.64e-2)" "unprognostic (5.05e-2)" "unprognostic (8.54e-2)" LRRC7 "densin-180, KIAA1365" ENSG00000033122 "Leucine rich repeat containing 7" 1 69567922-70151945 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 7.9" "Cell type enhanced" "Detected in many" "Bergmann glia: 415.4;Brain excitatory neurons: 1307.9;Brain inhibitory neurons: 1786.4;Oligodendrocyte progenitor cells: 1214.3;Oligodendrocytes: 442.2;Other brain neurons: 760.9;Retinal bipolar cells: 762.2;Retinal ganglion cells: 312.9" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in single" "Prostate Adenocarcinoma (TCGA): 1.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 2.7" "Adipose subcutaneous - Smooth muscle cells, Colon - Enteric glia cells, Liver - Hepatic stellate cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA005625 Supported "Nucleoplasm,Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 35: Neurons - Synaptic function & neurogenesis" 8 "Plasma membrane, Cytosol" "Nucleoplasm, Centrosome" "HPA005625: " "unprognostic (4.32e-2)" "unprognostic (2.10e-1)" LRRC70 "LOC100130733, SLRN" ENSG00000186105 "Leucine rich repeat containing 70" Q7Z2Q7 5 62578819-62581446 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in single" "Platelets: 1.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney Renal Clear Cell Carcinoma (TCGA): 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" HPA013409 Uncertain NA NA 17000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 46: Brainstem - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" "HPA013409: " "unprognostic (1.49e-1)" "unprognostic (2.34e-1)" "unprognostic (2.16e-1)" "potential prognostic favorable (5.65e-7)" "unprognostic (1.20e-3)" "potential prognostic favorable (2.54e-4)" "unprognostic (4.17e-1)" "unprognostic (2.00e-1)" "unprognostic (1.38e-2)" "unprognostic (3.18e-2)" "unprognostic (7.21e-2)" LRRC71 "C1orf92, FLJ32884" ENSG00000160838 "Leucine rich repeat containing 71" Q8N4P6 1 156920632-156933094 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "choroid plexus: 10.8;fallopian tube: 11.6;testis: 23.6" "Cell type enhanced" "Detected in some" "Early spermatids: 268.4;Endometrial ciliated cells: 50.8;Ependymal cells: 66.7;Fallopian tube ciliated cells: 127.7;Late primary spermatocytes: 187.1;Late spermatids: 969.3;Respiratory ciliated cells: 126.3" "Cell type enriched" "Detected in some" 13 "ependymal cell: 74.8" "Cancer enriched" "Detected in single" 4 "Uterine Corpus Endometrial Carcinoma (TCGA): 3.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 1 "unprognostic (6.87e-1)" LRRC72 "CFAP279, FAP279" ENSG00000205858 "Leucine rich repeat containing 72" A6NJI9 7 16526825-16581568 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 24 "testis: 2.4" "Group enriched" "Detected in some" 6 "Early spermatids: 196.7;Late spermatids: 51.4" "Cell type enhanced" "Detected in single" "hippocampal dentate gyrus: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" HPA020554 Uncertain NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 5: Rhabdoid - Unknown function" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" "HPA020554: " LRRC73 "C6orf154, dJ337H4.2" ENSG00000204052 "Leucine rich repeat containing 73" Q5JTD7 6 43506968-43510346 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 12.2;testis: 42.3" "Group enriched" "Detected in many" 5 "Early spermatids: 374.5;Late primary spermatocytes: 457.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adrenal gland - Adrenal cortex cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary gland ductal cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046698 Enhanced Approved "Nuclear bodies,Cytosol" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 51: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 19 Cytosol "Nuclear bodies" "HPA046698: " "unprognostic (9.83e-2)" "unprognostic (2.36e-3)" "potential prognostic unfavorable (6.97e-4)" "unprognostic (1.65e-1)" "unprognostic (3.81e-3)" "unprognostic (1.78e-1)" "unprognostic (2.05e-2)" "unprognostic (9.51e-2)" "unprognostic (7.84e-2)" "unprognostic (7.65e-2)" "unprognostic (3.58e-2)" "unprognostic (2.05e-1)" "unprognostic (1.33e-1)" "potential prognostic unfavorable (1.62e-4)" "unprognostic (1.13e-1)" LRRC74A "C14orf166B, LRRC74" ENSG00000100565 "Leucine rich repeat containing 74A" Q0VAA2 14 76826372-76870304 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 17 "testis: 6.2" "Group enriched" "Detected in some" 4 "Early spermatids: 114.2;Late spermatids: 186.0" "Cell type enriched" "Detected in some" 7 "central nervous system macrophage: 14.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA035094 Uncertain NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" "HPA035094: " LRRC74B ENSG00000187905 "Leucine rich repeat containing 74B" Q6ZQY2 22 21045946-21064168 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 1.6;fallopian tube: 2.5;testis: 1.2" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 104.1;Endometrial ciliated cells: 39.5;Ependymal cells: 333.2;Epididymal efferent duct ciliated cells: 49.5;Fallopian tube ciliated cells: 52.5;Respiratory ciliated cells: 61.8" "Group enriched" "Detected in many" 22 "choroid plexus epithelial cell: 79.3;ependymal cell: 308.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA049947 Uncertain NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 48: Non-specific - Mixed function" "Cluster 34: Ciliated cells - Cilia assembly & function" "HPA049947: " LRRC75A "C17orf76, FAM211A, FLJ35696" ENSG00000181350 "Leucine rich repeat containing 75A" Q8NAA5 17 16441577-16492193 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 44.6" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 1.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Hepatic stellate cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028528, HPA065840" Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 51: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 17: Non-specific - RNA processing" Nucleoplasm "Nucleoli, Cytosol" "HPA028528: , HPA065840: " "unprognostic (7.69e-3)" "unprognostic (5.11e-3)" "unprognostic (1.42e-1)" "unprognostic (1.57e-1)" "unprognostic (1.16e-1)" "unprognostic (9.48e-2)" "unprognostic (3.21e-2)" "unprognostic (2.68e-2)" "unprognostic (1.51e-1)" "unprognostic (5.56e-3)" "unprognostic (3.44e-2)" "unprognostic (2.17e-1)" "unprognostic (7.15e-3)" "unprognostic (2.53e-2)" "unprognostic (5.81e-2)" "unprognostic (4.01e-3)" "unprognostic (1.56e-1)" "unprognostic (6.61e-2)" "unprognostic (1.02e-2)" "unprognostic (8.46e-2)" "unprognostic (2.97e-1)" "potential prognostic favorable (6.09e-4)" "unprognostic (3.85e-1)" "unprognostic (6.06e-3)" "unprognostic (3.49e-2)" "unprognostic (1.73e-1)" "unprognostic (2.71e-2)" "potential prognostic unfavorable (4.97e-4)" LRRC75B "C22orf36, FAM211B, MGC131773" ENSG00000178026 "Leucine rich repeat containing 75B" Q2VPJ9 22 24585620-24593208 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 8.6" "Cell type enhanced" "Detected in many" "Cholangiocytes: 35.6;Enterocytes: 45.4;Hepatocytes: 29.0;Mucous neck cells: 38.7;Müller glia: 34.6;Proximal tubule cells: 53.5;Sertoli cells: 42.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Prostate - Prostate glandular cells, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002540 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 67: Testis - Mixed function" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 27: Breast cancer - Unknown function" "Cluster 88: Proximal tubular cells - Transmembrane transport" "Nucleoplasm, Cytosol" "HPA002540: " "unprognostic (1.08e-2)" "unprognostic (7.31e-3)" "unprognostic (8.06e-2)" "unprognostic (2.59e-1)" "unprognostic (3.22e-1)" "unprognostic (2.65e-1)" "unprognostic (1.41e-1)" "unprognostic (4.35e-2)" "unprognostic (1.84e-1)" "unprognostic (2.05e-2)" "unprognostic (3.53e-2)" "unprognostic (1.65e-1)" "unprognostic (2.60e-2)" "unprognostic (1.27e-1)" "unprognostic (6.52e-2)" "unprognostic (1.40e-1)" "unprognostic (6.17e-2)" "unprognostic (2.59e-1)" "unprognostic (3.72e-2)" "unprognostic (1.67e-1)" "unprognostic (3.02e-2)" "unprognostic (1.93e-1)" "unprognostic (9.00e-3)" LRRC8A "FLJ10337, KIAA1437, LRRC8, SWELL1" ENSG00000136802 "Leucine rich repeat containing 8 VRAC subunit A" Q8IWT6 9 128882133-128918039 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Differentiation, Ion transport, Spermatogenesis, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bergmann glia: 230.8;Esophageal apical cells: 349.8;Esophageal basal cells: 180.1;Esophageal suprabasal cells: 294.8;Ocular epithelial cells: 253.7;Prostatic hillock cells: 215.6;Suprabasal keratinocytes: 171.5" "Group enriched" "Detected in all" 4 "astrocyte: 91.0;Bergmann glia: 222.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pituitary gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 74: Non-specific - Signal transduction" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 10 "unprognostic (1.29e-1)" "unprognostic (5.14e-3)" "unprognostic (2.49e-1)" "unprognostic (1.10e-1)" "unprognostic (5.13e-2)" "potential prognostic unfavorable (1.37e-5)" "unprognostic (1.20e-1)" "unprognostic (4.03e-2)" "unprognostic (1.12e-3)" "unprognostic (3.72e-1)" "validated prognostic favorable (8.32e-8)" "validated prognostic favorable (7.45e-4)" "unprognostic (1.45e-2)" "unprognostic (3.80e-2)" "unprognostic (7.80e-2)" "unprognostic (5.07e-3)" "potential prognostic unfavorable (3.71e-5)" "unprognostic (5.40e-2)" "unprognostic (1.61e-1)" "unprognostic (4.58e-2)" "unprognostic (2.03e-1)" "unprognostic (1.03e-3)" "unprognostic (2.62e-1)" "unprognostic (5.70e-2)" "unprognostic (2.38e-1)" "unprognostic (4.45e-2)" "unprognostic (5.58e-2)" "unprognostic (2.84e-1)" "unprognostic (3.49e-1)" "unprognostic (5.22e-2)" "unprognostic (1.40e-2)" LRRC8B "KIAA0231, TA-LRRP" ENSG00000197147 "Leucine rich repeat containing 8 VRAC subunit B" Q6P9F7 1 89524829-89597861 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 20.9" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 196.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017950 Uncertain NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 35: Neurons - Synaptic function & neurogenesis" 6 "HPA017950: " "unprognostic (1.42e-3)" "unprognostic (2.47e-2)" "potential prognostic favorable (4.48e-4)" "unprognostic (2.74e-1)" "unprognostic (1.16e-3)" "unprognostic (1.54e-1)" "unprognostic (1.19e-1)" "potential prognostic favorable (4.38e-5)" "unprognostic (4.05e-2)" "unprognostic (4.59e-1)" "potential prognostic favorable (1.33e-5)" "unprognostic (2.68e-2)" "unprognostic (7.67e-2)" "unprognostic (2.23e-2)" "unprognostic (3.57e-1)" "unprognostic (1.85e-1)" "unprognostic (1.31e-1)" "unprognostic (2.98e-2)" "potential prognostic favorable (9.09e-4)" "unprognostic (6.81e-2)" "unprognostic (8.55e-2)" "unprognostic (3.91e-3)" "unprognostic (9.97e-2)" "unprognostic (1.07e-1)" "unprognostic (3.06e-2)" "unprognostic (1.59e-1)" "unprognostic (6.28e-2)" "unprognostic (1.29e-1)" "unprognostic (2.54e-1)" "unprognostic (9.35e-3)" "unprognostic (5.15e-2)" LRRC8C AD158 ENSG00000171488 "Leucine rich repeat containing 8 VRAC subunit C" Q8TDW0 1 89633072-89769903 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 7 "Early spermatids: 4.9;Late spermatids: 9.5" "Cell type enhanced" "Detected in single" "endothelial cell: 1.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "dendritic cells: 9.0;monocytes: 6.6;T-cells: 11.3" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Lung - Endothelial cells, Minor Salivary Gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029347 Uncertain Uncertain "Golgi apparatus" No No "Cluster 33: Non-specific - ATP binding" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 8: Immune cells - Immune response" "Cluster 6: Leukemia - Signal transduction" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 5 "Golgi apparatus" "HPA029347: " "unprognostic (2.74e-1)" "unprognostic (3.24e-2)" "unprognostic (3.50e-3)" "unprognostic (6.20e-2)" "unprognostic (8.73e-2)" "unprognostic (9.78e-2)" "unprognostic (6.92e-2)" "unprognostic (3.22e-2)" "unprognostic (4.23e-3)" "unprognostic (5.68e-2)" "potential prognostic favorable (1.09e-6)" "unprognostic (2.13e-3)" "unprognostic (2.85e-2)" "unprognostic (3.30e-2)" "unprognostic (1.22e-1)" "unprognostic (2.14e-2)" "unprognostic (3.02e-2)" "unprognostic (2.03e-2)" "unprognostic (5.12e-1)" "unprognostic (1.77e-2)" "unprognostic (2.48e-1)" "unprognostic (1.71e-1)" "unprognostic (2.27e-3)" "unprognostic (2.13e-1)" "unprognostic (3.98e-1)" "unprognostic (6.66e-2)" "unprognostic (2.20e-1)" "unprognostic (1.80e-2)" "unprognostic (8.81e-2)" "unprognostic (7.47e-3)" "unprognostic (2.57e-2)" LRRC8D "FLJ10470, LRRC5" ENSG00000171492 "Leucine rich repeat containing 8 VRAC subunit D" Q7L1W4 1 89821014-89936611 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Megakaryocytes: 55.6;Pituicytes/FSCs: 57.6;Platelets: 45.2;Retinal pigment epithelial cells: 42.6" "Cell type enhanced" "Detected in all" "oligodendrocyte: 40.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA No "Cluster 33: Non-specific - ATP binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 2 "unprognostic (3.57e-2)" "unprognostic (3.48e-2)" "unprognostic (1.06e-1)" "unprognostic (2.19e-1)" "unprognostic (1.39e-3)" "unprognostic (3.63e-1)" "unprognostic (1.13e-1)" "unprognostic (7.21e-3)" "unprognostic (2.42e-1)" "unprognostic (1.66e-3)" "potential prognostic favorable (1.79e-5)" "unprognostic (6.65e-2)" "unprognostic (1.41e-1)" "unprognostic (6.29e-3)" "unprognostic (3.53e-1)" "unprognostic (1.46e-1)" "unprognostic (1.49e-1)" "unprognostic (6.48e-3)" "potential prognostic favorable (3.52e-4)" "unprognostic (2.48e-1)" "unprognostic (2.04e-2)" "unprognostic (3.66e-1)" "unprognostic (2.97e-2)" "unprognostic (2.37e-1)" "unprognostic (2.71e-3)" "unprognostic (6.09e-2)" "unprognostic (1.79e-1)" "unprognostic (1.75e-1)" "unprognostic (1.49e-1)" "unprognostic (1.41e-2)" "unprognostic (7.35e-2)" LRRC8E FLJ23420 ENSG00000171017 "Leucine rich repeat containing 8 VRAC subunit E" Q6NSJ5 19 7888505-7902021 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 13.8;Breast secretory cells: 13.6;Endometrial glandular cells: 16.4;Endometrial luminal cells: 16.4;Esophageal apical cells: 21.5;Esophageal basal cells: 21.4;Esophageal suprabasal cells: 22.0;Ocular epithelial cells: 17.3;Pancreatic duct cells: 17.4;Suprabasal keratinocytes: 18.7" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Lung - Alveolar cells type 2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA020466 Uncertain NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 58: Skin - Keratinization" "Cluster 48: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 85: Squamous epithelial cells - Keratinization" 54 "HPA020466: " "unprognostic (3.76e-2)" "unprognostic (2.25e-2)" "unprognostic (5.86e-2)" "unprognostic (1.78e-2)" "unprognostic (5.67e-2)" "unprognostic (8.72e-2)" "unprognostic (1.66e-3)" "potential prognostic unfavorable (5.65e-6)" "unprognostic (9.83e-2)" "unprognostic (1.87e-2)" "potential prognostic unfavorable (2.20e-5)" "unprognostic (3.30e-2)" "unprognostic (1.76e-1)" "unprognostic (8.75e-2)" "unprognostic (2.29e-1)" "unprognostic (2.76e-1)" "unprognostic (3.21e-2)" "unprognostic (1.69e-1)" "unprognostic (1.56e-1)" "unprognostic (2.70e-1)" "unprognostic (3.91e-1)" "potential prognostic unfavorable (6.20e-5)" "unprognostic (2.56e-2)" "unprognostic (2.49e-1)" "unprognostic (2.17e-1)" "unprognostic (1.25e-1)" "unprognostic (6.52e-2)" "unprognostic (8.90e-3)" "unprognostic (4.05e-2)" "unprognostic (1.52e-1)" "unprognostic (4.78e-2)" LRRC9 FLJ46156 ENSG00000131951 "Leucine rich repeat containing 9" Q6ZRR7 14 59919713-60066817 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "choroid plexus: 2.5;testis: 5.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 111.1;Choroid plexus epithelial cells: 384.7;Early spermatids: 251.2;Ependymal cells: 885.1;Epicardial cells: 97.8;Epididymal efferent duct ciliated cells: 195.6;Late spermatids: 139.1;Prostatic glandular cells: 323.9" "Group enriched" "Detected in all" 10 "choroid plexus epithelial cell: 350.5;ependymal cell: 922.2" "Cancer enhanced" "Detected in some" "Kidney Chromophobe (TCGA): 1.4;Prostate Adenocarcinoma (TCGA): 1.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA040965, HPA041381, HPA077675" Uncertain Approved "Nucleoplasm,Nuclear bodies,Plasma membrane,Cell Junctions" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" "Plasma membrane, Cell Junctions" "Nucleoplasm, Nuclear bodies" "HPA040965: , HPA041381: , HPA077675: " "potential prognostic unfavorable (5.01e-4)" "unprognostic (3.08e-1)" "unprognostic (4.76e-2)" LRRCC1 "CLERC, KIAA1764, VFL1" ENSG00000133739 "Leucine rich repeat and coiled-coil centrosomal protein 1" Q9C099 8 85107215-85146080 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 31.3" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 109.5;Early spermatids: 154.9;Erythrocyte progenitors: 96.4;Late primary spermatocytes: 389.0;Late spermatids: 246.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012893, HPA075880" Uncertain Supported "Vesicles,Primary cilium,Primary cilium tip,Centrosome,Basal body,Cytosol" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 67: Testis - Mixed function" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 1 "Centrosome, Basal body" "Vesicles, Primary cilium, Primary cilium tip, Cytosol" "HPA012893: , HPA075880: " "unprognostic (2.40e-2)" "unprognostic (1.03e-2)" "unprognostic (3.62e-1)" "unprognostic (5.44e-2)" "unprognostic (7.05e-2)" "unprognostic (7.71e-3)" "unprognostic (3.35e-1)" "unprognostic (9.94e-2)" "unprognostic (1.36e-1)" "unprognostic (2.26e-1)" "unprognostic (1.15e-3)" "unprognostic (4.81e-2)" "unprognostic (6.77e-2)" "unprognostic (8.28e-3)" "unprognostic (1.56e-2)" "unprognostic (6.74e-2)" "unprognostic (5.44e-2)" "unprognostic (5.14e-2)" "unprognostic (1.11e-1)" "unprognostic (1.87e-1)" "unprognostic (2.49e-2)" "unprognostic (1.18e-1)" "unprognostic (2.05e-1)" "unprognostic (1.05e-1)" "unprognostic (1.52e-2)" "unprognostic (9.77e-2)" "unprognostic (8.32e-2)" "unprognostic (8.33e-2)" "unprognostic (1.70e-1)" "unprognostic (2.06e-2)" "unprognostic (6.31e-2)" LRRD1 IMAGE:4798971 ENSG00000240720 "Leucine rich repeats and death domain containing 1" A4D1F6 7 92141643-92179531 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 29 "testis: 13.8" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 1.6;Early spermatids: 4.0;Late spermatids: 11.9;Loop of henle epithelial cells: 1.6;Papillary tip epithelial cells: 1.1;Podocytes: 1.5;Proximal tubule cells: 1.6;Renal collecting duct intercalated cells: 2.2;Renal collecting duct principal cells: 1.6;Renal connecting tubule cells: 1.0" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA079440 Supported NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 56: Non-specific - Sensory perception" "Cluster 105: Non-specific - Mixed function" "HPA079440: " "unprognostic (1.34e-2)" "unprognostic (8.94e-2)" LRRFIP1 "FLAP-1, FLIIAP1, GCF-2, GCF2, HUFI-1, TRIP" ENSG00000124831 "LRR binding FLII interacting protein 1" Q32MZ4 2 237627587-237813682 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 1922.5;Urothelial cells: 1339.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006979 Approved Supported "Plasma membrane,Cytosol" NA NA 600000 "Cluster 7: Non-specific - Innate immune response" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 15 Cytosol "Plasma membrane" "HPA006979: " "unprognostic (8.69e-3)" "unprognostic (7.84e-2)" "unprognostic (2.43e-3)" "unprognostic (1.29e-2)" "unprognostic (9.66e-2)" "unprognostic (1.18e-2)" "unprognostic (1.49e-2)" "unprognostic (1.26e-3)" "unprognostic (1.19e-1)" "unprognostic (1.14e-2)" "potential prognostic favorable (6.06e-4)" "unprognostic (3.37e-1)" "unprognostic (2.79e-1)" "unprognostic (1.02e-1)" "unprognostic (2.66e-1)" "unprognostic (1.66e-2)" "unprognostic (1.04e-1)" "unprognostic (1.00e-2)" "unprognostic (9.05e-2)" "unprognostic (1.64e-1)" "unprognostic (1.87e-1)" "unprognostic (6.01e-3)" "potential prognostic unfavorable (3.37e-4)" "unprognostic (1.36e-1)" "unprognostic (5.21e-2)" "unprognostic (7.18e-2)" "unprognostic (6.29e-2)" "unprognostic (1.92e-1)" "unprognostic (2.11e-1)" "unprognostic (1.25e-1)" "unprognostic (1.38e-1)" LRRFIP2 HUFI-2 ENSG00000093167 "LRR binding FLII interacting protein 2" Q9Y608 3 37052626-37183689 "Predicted intracellular proteins, Transcription factors" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1232.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035956, HPA042023" Uncertain Approved "Plasma membrane,Actin filaments" NA NA 250000 "Cluster 45: Eosinophils - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 51: Secretory epithelial cells - Mixed function" 13 "Plasma membrane, Actin filaments" "HPA035956: , HPA042023: " "unprognostic (1.39e-1)" "unprognostic (2.88e-2)" "unprognostic (6.62e-2)" "unprognostic (2.43e-1)" "unprognostic (6.02e-2)" "unprognostic (1.92e-1)" "unprognostic (3.69e-1)" "unprognostic (2.73e-2)" "unprognostic (1.04e-1)" "potential prognostic unfavorable (5.04e-6)" "unprognostic (3.42e-3)" "unprognostic (3.87e-2)" "potential prognostic favorable (5.75e-4)" "unprognostic (1.02e-1)" "unprognostic (3.69e-1)" "unprognostic (8.88e-2)" "unprognostic (1.70e-1)" "unprognostic (1.02e-1)" "unprognostic (1.82e-1)" "unprognostic (3.89e-1)" "unprognostic (8.65e-2)" "unprognostic (1.41e-3)" "unprognostic (1.19e-2)" "unprognostic (7.50e-3)" "unprognostic (3.85e-1)" "unprognostic (2.47e-1)" "unprognostic (1.95e-2)" "unprognostic (6.56e-2)" "unprognostic (3.17e-1)" "potential prognostic unfavorable (8.11e-4)" "unprognostic (4.58e-2)" LRRIQ1 "FLJ12303, KIAA1801" ENSG00000133640 "Leucine rich repeats and IQ motif containing 1" Q96JM4 12 85036314-85264457 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 13.3;fallopian tube: 12.9;testis: 14.5" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 611.0;Early spermatids: 416.1;Endometrial ciliated cells: 671.9;Ependymal cells: 1460.9;Epididymal efferent duct ciliated cells: 858.7;Fallopian tube ciliated cells: 820.8;Late primary spermatocytes: 607.5;Late spermatids: 357.4;Respiratory ciliated cells: 1857.0;Respiratory deuterosomal cells: 300.6;Rod photoreceptor cells: 303.0" "Group enriched" "Detected in all" 11 "choroid plexus epithelial cell: 556.5;ependymal cell: 1608.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Adipose visceral - Mesothelial cells, Colon - Enteric glia cells, Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA046162 Uncertain NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" 1 "HPA046162: " "unprognostic (2.59e-1)" "unprognostic (1.88e-2)" "unprognostic (1.32e-1)" "unprognostic (2.23e-2)" "unprognostic (2.57e-1)" "unprognostic (7.56e-3)" "unprognostic (6.08e-2)" "unprognostic (3.49e-1)" "unprognostic (7.33e-2)" "unprognostic (2.85e-1)" "unprognostic (1.58e-1)" "unprognostic (2.24e-2)" "unprognostic (4.03e-1)" "unprognostic (9.67e-3)" LRRIQ3 "LRRC44, MGC22773" ENSG00000162620 "Leucine rich repeats and IQ motif containing 3" A6PVS8 1 74026015-74198187 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "testis: 19.1" "Cell type enhanced" "Detected in many" "Adipocytes: 129.2;Early primary spermatocytes: 122.3;Early spermatids: 194.8;Ependymal cells: 63.8;Late primary spermatocytes: 474.9;Late spermatids: 123.4;Respiratory ciliated cells: 62.5" "Cell type enhanced" "Detected in many" "ependymal cell: 67.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA030799 Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 47: Testis - Mixed function" "Cluster 3: Choroid plexus - Cilium" "Cluster 70: DU4475 - Unknown function" "Cluster 89: Adipocytes - Lipid metabolism" 2 "Plasma membrane" Nucleoplasm "HPA030799: " "unprognostic (4.70e-2)" "unprognostic (2.94e-2)" "unprognostic (3.38e-1)" "unprognostic (1.16e-1)" LRRIQ4 LRRC64 ENSG00000188306 "Leucine rich repeats and IQ motif containing 4" A6NIV6 3 169812870-169837773 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "testis: 2.5" "Group enriched" "Detected in some" 5 "Early spermatids: 67.2;Late spermatids: 40.7" "Cell type enhanced" "Detected in many" "ependymal cell: 7.0" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Gallbladder cancer: 1.2" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA036271, HPA036706" Uncertain Approved Mitochondria NA NA "Cluster 21: Testis - Mixed function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" Mitochondria "HPA036271: , HPA036706: " "unprognostic (4.48e-2)" "unprognostic (6.03e-2)" "unprognostic (2.83e-2)" LRRK1 "FLJ23119, KIAA1790, RIPK6, ROCO1" ENSG00000154237 "Leucine rich repeat kinase 1" Q38SD2 15 100919327-101078257 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "cDC: 177.4;Leydig cells: 199.5;Microglia: 643.8;pDCs: 212.5;Plasma cells: 257.9" "Cell type enriched" "Detected in all" 5 "central nervous system macrophage: 745.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 1.3" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Spleen - B-cells (Spleen), Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010537 Uncertain Supported Mitochondria,Cytosol NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 53: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 18 Cytosol Mitochondria "HPA010537: " "unprognostic (5.23e-2)" "unprognostic (5.39e-2)" "unprognostic (2.56e-2)" "unprognostic (4.23e-2)" "unprognostic (2.75e-1)" "unprognostic (6.51e-2)" "unprognostic (1.71e-1)" "unprognostic (2.75e-1)" "unprognostic (4.14e-2)" "unprognostic (2.45e-3)" "unprognostic (4.24e-2)" "unprognostic (2.52e-2)" "unprognostic (4.61e-2)" "unprognostic (3.72e-1)" "unprognostic (7.43e-3)" "unprognostic (1.26e-1)" "unprognostic (2.92e-1)" "unprognostic (5.61e-2)" "unprognostic (6.26e-2)" "unprognostic (5.66e-2)" "unprognostic (2.04e-2)" "unprognostic (1.73e-1)" "unprognostic (3.11e-2)" "unprognostic (2.23e-3)" "unprognostic (4.75e-2)" "unprognostic (1.36e-1)" "unprognostic (1.31e-1)" "unprognostic (5.09e-2)" "unprognostic (2.70e-1)" LRRK2 "DKFZp434H2111, FLJ45829, PARK8, RIPK7, ROCO2" ENSG00000188906 "Leucine rich repeat kinase 2" Q5S007 12 40196744-40369285 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Autophagy, Differentiation" "GTPase activation, Hydrolase, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lung: 49.4" "Group enriched" "Detected in many" 4 "Alveolar cells type 2: 2140.9;Neutrophils: 2171.3" "Cell type enhanced" "Detected in all" "oligodendrocyte precursor cell: 470.3" "Group enriched" "Detected in many" 6 "Kidney Renal Clear Cell Carcinoma (TCGA): 22.5;Kidney Renal Papillary Cell Carcinoma (TCGA): 40.1;Lung Adenocarcinoma (TCGA): 12.5;Thyroid Carcinoma (TCGA): 33.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 8 "neutrophil: 58.3" "Lineage enriched" "Detected in many" 8 "granulocytes: 58.3" "Cancer enhanced" "Detected in some" "Kidney cancer: 3.3;lymphoma: 3.2;skin cancer: 3.4" "Adrenal gland - Adrenal cortex cells, Lung - Alveolar cells type 2, Prostate - Fibroblasts, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014293, CAB037160" Approved Approved "Nucleoplasm,Nuclear membrane,Vesicles,Basal body,Cytosol" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 13: Lung - Secretion" "Cluster 53: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 213 "Vesicles, Basal body" "Nucleoplasm, Nuclear membrane, Cytosol" "CAB037160: , HPA014293: " "unprognostic (6.99e-2)" "unprognostic (1.99e-1)" "unprognostic (3.39e-2)" "unprognostic (7.38e-3)" "unprognostic (9.38e-2)" "potential prognostic favorable (1.14e-11)" "unprognostic (1.03e-2)" "unprognostic (1.23e-1)" "unprognostic (3.11e-2)" "unprognostic (3.98e-2)" "unprognostic (3.06e-2)" "unprognostic (1.30e-2)" "unprognostic (2.32e-1)" "unprognostic (2.50e-1)" "unprognostic (1.96e-1)" "unprognostic (2.49e-2)" "unprognostic (3.35e-1)" "unprognostic (7.97e-2)" "unprognostic (3.22e-1)" "unprognostic (1.90e-2)" LRRN1 FIGLER3 ENSG00000175928 "Leucine rich repeat neuronal 1" Q6UXK5 3 3799431-3849834 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 15.7" "Cell type enhanced" "Detected in many" "Astrocytes: 80.9;Brain excitatory neurons: 77.3;Brain inhibitory neurons: 156.8;Ependymal cells: 131.1;Oligodendrocyte progenitor cells: 549.8;Pituitary stem cells: 113.4;Sertoli cells: 105.8" "Cell type enhanced" "Detected in all" "oligodendrocyte precursor cell: 626.8" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 23.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 12 "testis cancer: 96.2" "Adipose visceral - Mesothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011071 Enhanced Approved "Endoplasmic reticulum,Golgi apparatus,Vesicles,Centriolar satellite,Basal body" NA NA 1600000 "Cluster 73: Brain - Neuronal signaling" "Cluster 49: Hindbrain - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 1 "Endoplasmic reticulum" "Golgi apparatus, Vesicles, Centriolar satellite, Basal body" "HPA011071: " "potential prognostic favorable (6.92e-4)" "unprognostic (3.45e-2)" "unprognostic (2.30e-2)" "unprognostic (6.87e-2)" "unprognostic (9.13e-2)" "unprognostic (8.28e-2)" "unprognostic (1.91e-2)" "unprognostic (7.28e-2)" "unprognostic (5.77e-2)" "unprognostic (3.39e-1)" "unprognostic (4.25e-2)" "unprognostic (1.44e-1)" "unprognostic (4.85e-1)" "unprognostic (7.70e-3)" "unprognostic (2.07e-2)" "unprognostic (1.11e-1)" "unprognostic (3.50e-1)" "unprognostic (8.58e-2)" "unprognostic (1.76e-3)" "unprognostic (1.56e-1)" "unprognostic (1.98e-1)" "unprognostic (3.84e-2)" LRRN2 "FIGLER7, GAC1, LRANK1, LRRN5" ENSG00000170382 "Leucine rich repeat neuronal 2" O75325 1 204617170-204685738 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 20.2" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 77.3;Brain inhibitory neurons: 82.1;Choroid plexus epithelial cells: 176.9;Corticotrophs: 93.5;Ependymal cells: 89.4;Gonadotrophs: 87.6;Oligodendrocyte progenitor cells: 69.7;Other brain neurons: 68.8;Renal collecting duct intercalated cells: 64.6;Renal connecting tubule cells: 89.8;Retinal horizontal cells: 174.3" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 7 "Breast Invasive Carcinoma (TCGA): 15.7;Glioblastoma Multiforme (TCGA): 48.9;Kidney Chromophobe (TCGA): 36.7;Ovary Serous Cystadenocarcinoma (TCGA): 40.3;Uterine Corpus Endometrial Carcinoma (TCGA): 27.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 9.4;testis cancer: 9.0" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029124 Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 109: Neurons - Neuronal signaling" 2 "Endoplasmic reticulum" "HPA029124: " "unprognostic (1.44e-1)" "unprognostic (1.56e-2)" "unprognostic (3.90e-1)" "unprognostic (1.30e-3)" "unprognostic (1.74e-1)" "unprognostic (2.83e-1)" "unprognostic (1.04e-1)" "unprognostic (8.40e-3)" "unprognostic (6.59e-2)" "potential prognostic unfavorable (8.59e-4)" "unprognostic (4.65e-2)" "unprognostic (6.07e-2)" "unprognostic (3.42e-2)" "unprognostic (1.06e-3)" "unprognostic (7.67e-2)" "unprognostic (2.18e-1)" "unprognostic (6.05e-3)" "unprognostic (1.11e-1)" "unprognostic (1.65e-1)" "unprognostic (2.92e-2)" "unprognostic (7.32e-3)" "unprognostic (2.29e-1)" "unprognostic (1.31e-2)" "unprognostic (9.18e-2)" "unprognostic (1.37e-1)" "unprognostic (6.78e-3)" "unprognostic (9.35e-2)" "unprognostic (5.87e-2)" "unprognostic (3.33e-1)" LRRN3 "FIGLER5, FLJ11129, NLRR3" ENSG00000173114 "Leucine rich repeat neuronal 3" Q9H3W5 7 111091006-111125454 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 21.9;brain: 16.8;thyroid gland: 18.3" "Cell type enhanced" "Detected in many" "Adipocytes: 116.2;Adrenal cortex cells: 78.8;Adrenal medulla cells: 85.1;Astrocytes: 76.3;Brain inhibitory neurons: 83.2;Cardiomyocytes: 84.8;Epicardial cells: 150.1;Leydig cells: 87.7;Oligodendrocyte progenitor cells: 76.6;Other brain neurons: 69.0;Retinal amacrine cells: 121.7;Sertoli cells: 120.9;Thymic myoid cells: 69.3" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in some" 4 "Glioblastoma Multiforme (TCGA): 30.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "naive CD4 T-cell: 32.6;naive CD8 T-cell: 31.0" "Lineage enriched" "Detected in single" 70 "T-cells: 32.6" "Cancer enriched" "Detected in many" 4 "Neuroblastoma: 56.6" "Adrenal gland - Adrenal cortex cells, Prostate - Fibroblasts, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043820, HPA046792" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 36: Brain & Liver - Signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 89: Adipocytes - Lipid metabolism" 1 "Nucleoplasm, Cytosol" "HPA043820: , HPA046792: " "unprognostic (1.72e-1)" "unprognostic (1.75e-2)" "unprognostic (1.60e-1)" "unprognostic (3.90e-2)" "unprognostic (4.22e-2)" "unprognostic (8.21e-3)" "unprognostic (4.71e-1)" "potential prognostic favorable (4.71e-5)" "unprognostic (4.48e-1)" "unprognostic (1.20e-2)" "unprognostic (4.52e-3)" LRRN4 "C20orf75, dJ1056H1.1, NLRR4" ENSG00000125872 "Leucine rich repeat neuronal 4" Q8WUT4 20 6040546-6054060 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adipose tissue: 7.8;lung: 9.8" "Cell type enhanced" "Detected in some" "Adipocytes: 15.8;Alveolar cells type 1: 49.7;Cardiomyocytes: 29.9;Epicardial cells: 70.5;Mesothelial cells: 25.7;Oocytes: 13.8" "Cell type enhanced" "Detected in some" "medium spiny neuron: 1.9" "Group enriched" "Detected in some" 6 "Kidney Renal Papillary Cell Carcinoma (TCGA): 45.6;Lung Adenocarcinoma (TCGA): 12.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 49.3" "Adipose visceral - Mesothelial cells, Pancreas - Ductal cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA075974 Uncertain "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No 21000 "Cluster 13: Lung - Secretion" "Cluster 33: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 5 "Nucleoli, Nucleoli rim, Mitotic chromosome" "HPA075974: " "unprognostic (1.18e-1)" "unprognostic (1.04e-1)" "unprognostic (2.84e-1)" "potential prognostic favorable (7.86e-4)" "unprognostic (5.82e-2)" "unprognostic (1.86e-1)" "unprognostic (2.08e-1)" "unprognostic (6.48e-3)" "unprognostic (8.88e-2)" "unprognostic (4.53e-2)" LRRN4CL ENSG00000177363 "LRRN4 C-terminal like" Q8ND94 11 62686406-62689530 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Decidual stromal cells: 29.4;Endometrial stromal cells: 7.9;Fibro-adipogenic progenitors: 8.7;Fibroblasts: 47.2;Leydig cells: 23.1;Lymphatic endothelial cells: 19.8;Melanocytes: 25.6;Myosatellite cells: 22.9;Ovarian stromal cells: 18.3;Peritubular myoid cells: 18.3;Smooth muscle cells: 22.4" "Group enriched" "Detected in some" 6 "fibroblast: 19.6;pericyte: 5.7" "Cancer enriched" "Detected in many" 6 "Skin Cutaneous Melanoma (TCGA): 46.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Sarcoma: 2.8" "Adrenal gland - Adrenal cortex cells, Lung - Fibroblasts_2, Minor Salivary Gland - Fibroblasts, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblasts_2, Spleen - Smooth muscle cells, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" HPA050317 Enhanced Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 42 Nucleoplasm "Nuclear bodies" "HPA050317: " "unprognostic (2.47e-2)" "unprognostic (2.04e-1)" "unprognostic (1.67e-2)" "unprognostic (1.00e-2)" "unprognostic (6.36e-2)" "unprognostic (4.92e-1)" "unprognostic (1.07e-1)" "unprognostic (1.20e-1)" "potential prognostic favorable (8.50e-4)" "unprognostic (6.72e-3)" "unprognostic (7.01e-3)" "unprognostic (8.70e-3)" "unprognostic (2.38e-2)" "unprognostic (1.01e-1)" "unprognostic (1.73e-2)" "unprognostic (3.02e-3)" "unprognostic (2.86e-1)" "unprognostic (1.10e-1)" "unprognostic (1.25e-1)" "unprognostic (2.16e-1)" "unprognostic (3.17e-2)" "unprognostic (4.49e-2)" "unprognostic (9.65e-3)" "unprognostic (3.85e-2)" "unprognostic (7.80e-2)" LRRTM1 FLJ32082 ENSG00000162951 "Leucine rich repeat transmembrane neuronal 1" Q86UE6 2 80288351-80304752 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 21.8;salivary gland: 12.1" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 10.0;Brain inhibitory neurons: 18.7;Epididymal efferent duct absorptive cells: 23.8;Müller glia: 16.0;Oligodendrocyte progenitor cells: 11.6;Oligodendrocytes: 7.9;Other brain neurons: 12.2;Retinal amacrine cells: 11.3;Retinal ganglion cells: 15.5;Salivary acinar cells: 5.9;Schwann cells: 19.2" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 9 "Kidney Chromophobe (TCGA): 39.3;Ovary Serous Cystadenocarcinoma (TCGA): 49.4;Uterine Corpus Endometrial Carcinoma (TCGA): 34.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Neuroblastoma: 8.0;Rhabdoid: 7.3" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046607, HPA062660" Approved Approved "Golgi apparatus" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 35: Neurons - Synaptic function & neurogenesis" "Golgi apparatus" "HPA046607: , HPA062660: " "unprognostic (4.51e-1)" "unprognostic (1.58e-1)" "potential prognostic favorable (1.83e-5)" "unprognostic (2.16e-1)" "unprognostic (4.51e-2)" "unprognostic (9.31e-2)" "unprognostic (2.01e-1)" "unprognostic (1.10e-2)" "unprognostic (1.69e-1)" "unprognostic (1.17e-1)" "potential prognostic unfavorable (2.13e-4)" "unprognostic (2.30e-1)" LRRTM2 KIAA0416 ENSG00000146006 "Leucine rich repeat transmembrane neuronal 2" O43300 5 138868921-138875368 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 16.3" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 23.5;Brain inhibitory neurons: 33.7;Cardiomyocytes: 72.4;Epicardial cells: 79.6;Oligodendrocyte progenitor cells: 40.0;Oligodendrocytes: 26.4;Other brain neurons: 23.3;Retinal amacrine cells: 16.3" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in single" 8 "Glioblastoma Multiforme (TCGA): 7.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 12 "Neuroblastoma: 6.0" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 34: Non-specific - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 2 "unprognostic (8.25e-2)" "unprognostic (2.36e-2)" "unprognostic (2.64e-1)" "unprognostic (1.06e-1)" "unprognostic (1.17e-1)" "unprognostic (2.83e-2)" LRRTM3 ENSG00000198739 "Leucine rich repeat transmembrane neuronal 3" Q86VH5 10 66926036-67101551 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 2.4;brain: 10.4;pituitary gland: 2.7" "Cell type enriched" "Detected in many" 5 "Cardiomyocytes: 7362.5" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in single" 8 "Glioblastoma Multiforme (TCGA): 4.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Sarcoma: 1.4" "Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Pancreas - Beta cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 3 "unprognostic (9.87e-2)" "unprognostic (9.58e-3)" LRRTM4 FLJ12568 ENSG00000176204 "Leucine rich repeat transmembrane neuronal 4" Q86VH4 2 76747685-77593319 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 11.3;retina: 6.1" "Cell type enhanced" "Detected in many" "Bergmann glia: 2939.4;Brain excitatory neurons: 1982.3;Brain inhibitory neurons: 2339.3;Cone photoreceptor cells: 616.9;Fibro-adipogenic progenitors: 2593.0;Lactotrophs: 1243.8;Oligodendrocyte progenitor cells: 4091.6;Other brain neurons: 2302.9;Retinal bipolar cells: 1450.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.6" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Liver - Hepatocytes, Pituitary gland - Lactotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 18: Non-specific - Translation" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "unprognostic (9.64e-2)" "unprognostic (5.38e-2)" "unprognostic (4.06e-3)" "unprognostic (5.98e-2)" "unprognostic (2.92e-2)" "unprognostic (2.99e-1)" "potential prognostic favorable (3.89e-4)" "unprognostic (6.17e-2)" "unprognostic (3.74e-2)" "potential prognostic unfavorable (4.32e-4)" "unprognostic (1.10e-2)" "unprognostic (2.27e-2)" "unprognostic (1.05e-2)" "unprognostic (5.19e-2)" "unprognostic (3.03e-1)" "unprognostic (3.95e-2)" "unprognostic (3.57e-1)" "unprognostic (2.09e-2)" "unprognostic (2.59e-2)" "unprognostic (2.83e-2)" "unprognostic (2.30e-1)" "unprognostic (1.54e-2)" "unprognostic (1.09e-1)" "unprognostic (3.03e-1)" "unprognostic (6.64e-2)" LRSAM1 "CMT2P, FLJ31641, RIFLE, TAL" ENSG00000148356 "Leucine rich repeat and sterile alpha motif containing 1" Q6UWE0 9 127451489-127503499 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Autophagy, Protein transport, Transport, Ubl conjugation pathway" Transferase "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021403, HPA021844, CAB037304" Supported Approved Cytosol NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 24: Neurons - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Transcription" 16 Cytosol "CAB037304: , HPA021403: , HPA021844: " "unprognostic (8.84e-3)" "unprognostic (3.66e-2)" "unprognostic (2.66e-1)" "unprognostic (2.08e-2)" "unprognostic (6.10e-2)" "unprognostic (1.53e-2)" "unprognostic (3.00e-2)" "potential prognostic favorable (3.52e-4)" "unprognostic (5.78e-2)" "unprognostic (1.44e-2)" "potential prognostic favorable (5.13e-8)" "unprognostic (3.78e-2)" "unprognostic (8.32e-3)" "unprognostic (2.05e-1)" "unprognostic (7.42e-2)" "unprognostic (2.77e-1)" "unprognostic (2.52e-1)" "unprognostic (5.01e-2)" "unprognostic (4.86e-2)" "unprognostic (2.51e-2)" "unprognostic (1.93e-2)" "unprognostic (9.39e-3)" "unprognostic (3.26e-2)" "unprognostic (5.51e-2)" "unprognostic (1.76e-1)" "unprognostic (8.52e-2)" "unprognostic (1.37e-2)" "unprognostic (3.26e-1)" "unprognostic (5.66e-1)" "unprognostic (2.99e-1)" "unprognostic (1.45e-1)" LRTM1 HT017 ENSG00000144771 "Leucine rich repeats and transmembrane domains 1" Q9HBL6 3 54918231-54967088 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "retina: 73.1;skeletal muscle: 24.4" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 42.9;Cardiomyocytes: 41.7;Epicardial cells: 216.0;Myonuclei: 61.0;Retinal bipolar cells: 327.4;Retinal ganglion cells: 85.0;Syncytiotrophoblasts: 34.3" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in single" "Uterine Corpus Endometrial Carcinoma (TCGA): 1.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in many" "midbrain: 10.8" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 1 "unprognostic (1.21e-1)" LRTM2 ENSG00000166159 "Leucine rich repeats and transmembrane domains 2" Q8N967 12 1820267-1836753 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 10 "brain: 9.4" "Group enriched" "Detected in some" 17 "Brain excitatory neurons: 9.4;Brain inhibitory neurons: 17.0;Other brain neurons: 9.8" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 9 "Sarcoma: 4.3" "Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA055094, HPA062745" Uncertain Approved Cytosol NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 35: Neurons - Synaptic function & neurogenesis" Cytosol "HPA055094: , HPA062745: " "unprognostic (1.32e-1)" LRTOMT "CFAP111, COMT2, DFNB63, LRRC51, LRTOMT1, LRTOMT2" ENSG00000284922 "Leucine rich transmembrane and O-methyltransferase domain containing" Q8WZ04 11 72080331-72110782 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Catecholamine metabolism, Hearing, Neurotransmitter degradation" "Methyltransferase, Transferase" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "fallopian tube: 4.8;testis: 8.5" "Cell type enhanced" "Detected in some" "Adipocytes: 14.0;Cardiomyocytes: 51.6;Epicardial cells: 18.2;Late spermatids: 25.8;Mesothelial cells: 12.6;Platelets: 7.1" "Cell type enhanced" "Detected in some" "ependymal cell: 3.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA039949 Approved Uncertain Microtubules NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 16: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" Microtubules "HPA039949: " LRWD1 "CENP-33, DKFZp434K1815, ORCA" ENSG00000161036 "Leucine rich repeats and WD repeat domain containing 1" Q9UFC0 7 102464956-102473168 "Predicted intracellular proteins" "DNA replication" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 10 "testis: 272.4" "Group enriched" "Detected in many" 7 "Early spermatids: 897.5;Late primary spermatocytes: 1786.0" "Cell type enhanced" "Detected in all" "ependymal cell: 29.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021320 Enhanced Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Vesicles" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 79: Testis - Spermatogenesis" "Cluster 44: Non-specific - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 16 "Nucleoli, Nucleoli rim" "Nucleoplasm, Vesicles" "HPA021320: " "unprognostic (4.77e-2)" "unprognostic (3.01e-1)" "unprognostic (1.58e-2)" "unprognostic (8.24e-2)" "unprognostic (1.82e-1)" "unprognostic (9.07e-3)" "unprognostic (1.75e-2)" "unprognostic (3.32e-1)" "unprognostic (9.49e-3)" "unprognostic (1.11e-2)" "unprognostic (2.60e-2)" "unprognostic (2.43e-2)" "unprognostic (2.66e-1)" "unprognostic (1.75e-3)" "unprognostic (1.32e-2)" "unprognostic (1.29e-1)" "unprognostic (1.28e-1)" "unprognostic (2.65e-1)" "unprognostic (1.08e-1)" "unprognostic (3.01e-2)" "unprognostic (1.68e-1)" "potential prognostic favorable (1.80e-4)" "unprognostic (1.23e-1)" "unprognostic (2.61e-2)" "unprognostic (5.16e-1)" "unprognostic (1.31e-2)" "unprognostic (2.54e-1)" "unprognostic (6.53e-2)" "unprognostic (4.82e-2)" "unprognostic (4.01e-1)" "unprognostic (9.96e-3)" LSAMP "IGLON3, LAMP" ENSG00000185565 "Limbic system associated membrane protein" Q13449 3 115802363-117139389 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 56.9;retina: 37.7" "Cell type enhanced" "Detected in many" "Astrocytes: 8316.9;Bergmann glia: 6744.8;Brain excitatory neurons: 3274.4;Brain inhibitory neurons: 3777.3;Choroid plexus epithelial cells: 2700.1;Gonadotrophs: 2528.9;Leydig cells: 2509.1;Müller glia: 2697.3;Oligodendrocyte progenitor cells: 5356.3;Oligodendrocytes: 2509.2;Other brain neurons: 3212.0;Prostatic glandular cells: 2797.7;Retinal amacrine cells: 1905.0;Retinal horizontal cells: 4373.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 38.2;Kidney Chromophobe (TCGA): 37.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 16.3" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Cardiomyocytes, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Stomach - Fibroblasts, Testis - Peritubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054051, HPA076122" Enhanced Cytosol NA NA 18000000 "Cluster 73: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 28: Astrocytes - Homeostasis & neuron support" 12 Cytosol "HPA054051: , HPA076122: " "unprognostic (1.13e-3)" "unprognostic (1.51e-1)" "unprognostic (5.88e-2)" "unprognostic (1.44e-1)" "unprognostic (1.97e-1)" "unprognostic (1.04e-1)" "unprognostic (5.72e-2)" "unprognostic (1.31e-2)" "unprognostic (5.51e-3)" "unprognostic (1.13e-2)" "potential prognostic unfavorable (8.18e-5)" "unprognostic (1.52e-1)" "potential prognostic favorable (7.97e-5)" "unprognostic (1.16e-1)" "unprognostic (6.50e-2)" "unprognostic (3.69e-1)" "unprognostic (5.63e-2)" "unprognostic (1.57e-1)" "unprognostic (2.72e-1)" "unprognostic (6.57e-2)" "unprognostic (2.23e-1)" "unprognostic (2.02e-1)" "unprognostic (4.28e-3)" "unprognostic (3.41e-3)" "unprognostic (9.21e-3)" "unprognostic (1.26e-1)" "unprognostic (4.50e-3)" "unprognostic (1.22e-2)" LSG1 FLJ11301 ENSG00000041802 "Large 60S subunit nuclear export GTPase 1" Q9H089 3 194640791-194672463 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037704, HPA037705" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 63: Non-specific - Protein processing" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 30 "Nuclear bodies, Cytosol" Nucleoplasm "HPA037704: , HPA037705: " "unprognostic (2.79e-1)" "potential prognostic unfavorable (8.25e-4)" "unprognostic (1.27e-1)" "unprognostic (2.20e-1)" "unprognostic (1.76e-1)" "unprognostic (3.75e-1)" "unprognostic (4.18e-2)" "unprognostic (5.41e-3)" "unprognostic (9.76e-2)" "unprognostic (2.02e-3)" "unprognostic (1.92e-3)" "unprognostic (1.33e-1)" "unprognostic (9.20e-2)" "potential prognostic unfavorable (1.91e-5)" "unprognostic (1.38e-1)" "unprognostic (2.66e-3)" "unprognostic (2.71e-2)" "unprognostic (6.65e-2)" "unprognostic (5.04e-2)" "unprognostic (3.55e-1)" "unprognostic (6.99e-2)" "unprognostic (1.53e-2)" "unprognostic (5.56e-2)" "unprognostic (9.18e-3)" "unprognostic (6.44e-3)" "unprognostic (1.49e-1)" "unprognostic (8.84e-2)" "unprognostic (6.01e-2)" "unprognostic (2.24e-1)" "unprognostic (4.29e-2)" "unprognostic (2.78e-2)" LSM1 "CASM, YJL124C" ENSG00000175324 "LSM1 homolog, mRNA degradation associated" O15116 8 38163335-38176730 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 201.7;Esophageal suprabasal cells: 189.4;Extravillous trophoblasts: 183.8;Megakaryocytes: 173.1;Platelets: 184.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024601 Approved "Cytosol,Cytoplasmic bodies" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 40: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 58 "Cytoplasmic bodies" Cytosol "HPA024601: " "unprognostic (1.99e-2)" "potential prognostic unfavorable (7.04e-4)" "unprognostic (9.21e-3)" "unprognostic (1.78e-3)" "unprognostic (2.44e-2)" "unprognostic (1.28e-1)" "potential prognostic unfavorable (5.46e-4)" "unprognostic (1.08e-1)" "unprognostic (8.75e-2)" "unprognostic (2.03e-1)" "unprognostic (7.96e-2)" "unprognostic (1.75e-1)" "unprognostic (3.46e-1)" "unprognostic (5.89e-3)" "unprognostic (2.45e-2)" "unprognostic (1.75e-2)" "unprognostic (4.12e-1)" "unprognostic (1.73e-2)" "unprognostic (5.45e-3)" "unprognostic (3.57e-2)" "unprognostic (3.20e-2)" "unprognostic (2.05e-2)" "unprognostic (2.06e-1)" "unprognostic (2.68e-2)" "unprognostic (4.64e-2)" "unprognostic (1.97e-1)" "unprognostic (8.56e-3)" "unprognostic (4.18e-2)" "unprognostic (3.05e-1)" "unprognostic (1.22e-1)" "unprognostic (6.62e-2)" LSM10 MGC15749 ENSG00000181817 "LSM10, U7 small nuclear RNA associated" Q969L4 1 36391238-36397908 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 133.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048469 Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 7 Nucleoplasm "Nuclear bodies" "HPA048469: " "unprognostic (2.37e-1)" "unprognostic (1.96e-1)" "unprognostic (1.54e-1)" "unprognostic (1.25e-1)" "unprognostic (1.34e-1)" "unprognostic (1.73e-2)" "unprognostic (1.25e-1)" "unprognostic (4.68e-2)" "unprognostic (1.68e-1)" "potential prognostic unfavorable (1.37e-4)" "unprognostic (3.78e-3)" "unprognostic (3.90e-3)" "unprognostic (8.91e-2)" "potential prognostic unfavorable (1.73e-6)" "unprognostic (2.83e-3)" "unprognostic (2.63e-1)" "unprognostic (1.71e-1)" "unprognostic (9.12e-2)" "unprognostic (1.17e-1)" "unprognostic (4.53e-3)" "unprognostic (2.59e-1)" "unprognostic (2.83e-2)" "unprognostic (1.20e-1)" "unprognostic (8.60e-2)" "unprognostic (3.39e-1)" "unprognostic (6.41e-3)" "unprognostic (1.50e-1)" "unprognostic (1.66e-1)" "unprognostic (1.20e-1)" "unprognostic (1.63e-1)" "unprognostic (8.39e-2)" LSM11 FLJ38273 ENSG00000155858 "LSM11, U7 small nuclear RNA associated" P83369 5 157743712-157760709 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "mRNA processing" "Ribonucleoprotein, RNA-binding" "Aicardi-Goutieres syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Corticotrophs: 21.1;Late spermatids: 22.2;Smooth muscle cells: 20.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039587 Uncertain Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 64: Non-specific - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 20 Nucleoplasm "Nuclear bodies" "HPA039587: " "potential prognostic favorable (8.71e-4)" "unprognostic (4.26e-2)" "unprognostic (3.94e-1)" "unprognostic (2.31e-2)" "unprognostic (2.25e-1)" "unprognostic (1.37e-1)" "unprognostic (1.06e-1)" "unprognostic (1.84e-3)" "unprognostic (2.55e-1)" "unprognostic (1.37e-3)" "unprognostic (8.60e-3)" "unprognostic (8.17e-2)" "unprognostic (4.21e-3)" "unprognostic (4.68e-2)" "unprognostic (1.78e-3)" "unprognostic (4.40e-2)" "unprognostic (2.35e-1)" "unprognostic (3.17e-2)" "unprognostic (5.98e-2)" "unprognostic (1.96e-2)" "unprognostic (4.39e-2)" "unprognostic (4.72e-2)" "unprognostic (3.08e-1)" "unprognostic (9.53e-3)" "unprognostic (9.26e-2)" "unprognostic (1.14e-1)" "unprognostic (3.50e-1)" "unprognostic (4.00e-1)" "unprognostic (1.04e-1)" "unprognostic (1.36e-1)" LSM12 FLJ30656 ENSG00000161654 "LSM12 homolog" Q3MHD2 17 44034328-44067619 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051934 Approved Approved Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 29 Cytosol "HPA051934: " "unprognostic (8.35e-3)" "unprognostic (1.49e-1)" "unprognostic (2.45e-1)" "unprognostic (1.43e-2)" "unprognostic (3.96e-2)" "unprognostic (1.27e-1)" "unprognostic (6.24e-2)" "unprognostic (3.59e-2)" "potential prognostic unfavorable (8.87e-4)" "unprognostic (1.77e-1)" "unprognostic (6.20e-3)" "unprognostic (1.15e-1)" "unprognostic (1.67e-2)" "potential prognostic unfavorable (8.58e-4)" "unprognostic (1.31e-3)" "validated prognostic unfavorable (8.24e-4)" "validated prognostic unfavorable (6.24e-4)" "unprognostic (1.13e-1)" "unprognostic (6.18e-2)" "unprognostic (1.39e-1)" "unprognostic (1.49e-1)" "potential prognostic unfavorable (3.12e-4)" "unprognostic (7.90e-2)" "unprognostic (1.83e-1)" "unprognostic (3.79e-3)" "unprognostic (2.23e-1)" "unprognostic (4.45e-2)" "unprognostic (3.45e-2)" "unprognostic (3.15e-2)" "unprognostic (2.96e-2)" "unprognostic (1.80e-1)" LSM14A "C19orf13, DKFZP434D1335, FAM61A, RAP55, RAP55A" ENSG00000257103 "LSM14A mRNA processing body assembly factor" Q8ND56 19 34172504-34229288 "Essential proteins, Predicted intracellular proteins" "Translation regulation" "Developmental protein, Repressor, Ribonucleoprotein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 256.4;Distal convoluted tubule cells: 207.2;Ependymal cells: 173.4;Loop of henle epithelial cells: 199.4;Microglia: 180.8;Oligodendrocytes: 156.6;Podocytes: 193.8;Proximal tubule cells: 209.1;Renal collecting duct intercalated cells: 159.1;Renal collecting duct principal cells: 164.7;Renal connecting tubule cells: 197.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017961 Approved Supported "Cytosol,Cytoplasmic bodies" NA NA 9100 "Cluster 5: Non-specific - Cell proliferation" "Cluster 64: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 102: Non-specific - Mixed function" 62 "Cytoplasmic bodies" Cytosol "HPA017961: " "unprognostic (4.42e-3)" "unprognostic (9.65e-2)" "unprognostic (2.46e-1)" "unprognostic (2.07e-2)" "unprognostic (2.21e-1)" "unprognostic (4.29e-2)" "unprognostic (1.12e-1)" "unprognostic (4.69e-2)" "unprognostic (2.07e-1)" "unprognostic (1.87e-1)" "potential prognostic favorable (1.14e-5)" "unprognostic (2.49e-2)" "unprognostic (1.29e-1)" "unprognostic (1.46e-2)" "unprognostic (3.44e-2)" "unprognostic (8.40e-3)" "unprognostic (9.86e-2)" "unprognostic (1.97e-2)" "unprognostic (2.11e-1)" "unprognostic (3.17e-2)" "unprognostic (4.40e-2)" "unprognostic (1.95e-1)" "unprognostic (4.64e-2)" "unprognostic (1.13e-1)" "unprognostic (1.51e-1)" "unprognostic (4.07e-2)" "unprognostic (2.36e-2)" "unprognostic (1.33e-1)" "unprognostic (9.56e-3)" "unprognostic (2.06e-1)" "unprognostic (1.38e-1)" LSM14B "bA11M20.3, C20orf40, FAM61B, FLJ25473, FT005, LSM13, RAP55B" ENSG00000149657 "LSM family member 14B" Q9BX40 20 62122461-62135374 "Predicted intracellular proteins" "Differentiation, Meiosis, Oogenesis, Translation regulation" "Developmental protein, Ribonucleoprotein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 16 "Early spermatids: 287.3;Late spermatids: 901.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 2.3" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.3" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041274, HPA061189" Approved Approved Vesicles NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 15: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 19 Vesicles "HPA041274: , HPA061189: " "unprognostic (1.30e-1)" "unprognostic (9.95e-3)" "unprognostic (3.93e-2)" "unprognostic (2.25e-1)" "unprognostic (1.50e-1)" "unprognostic (1.59e-1)" "unprognostic (8.65e-2)" "unprognostic (1.38e-3)" "unprognostic (7.84e-2)" "unprognostic (1.42e-1)" "unprognostic (1.57e-3)" "unprognostic (4.21e-1)" "unprognostic (2.79e-1)" "validated prognostic unfavorable (1.78e-5)" "validated prognostic unfavorable (7.99e-4)" "unprognostic (1.26e-2)" "unprognostic (1.21e-1)" "unprognostic (1.52e-1)" "unprognostic (1.37e-2)" "unprognostic (1.54e-1)" "unprognostic (7.75e-2)" "unprognostic (7.94e-3)" "unprognostic (6.40e-2)" "unprognostic (2.20e-2)" "unprognostic (1.40e-2)" "unprognostic (3.38e-3)" "unprognostic (1.70e-1)" "unprognostic (9.52e-2)" "unprognostic (1.98e-1)" "unprognostic (2.14e-2)" "unprognostic (1.60e-1)" LSM2 "C6orf28, G7b, YBL026W" ENSG00000204392 "LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated" Q9Y333 6 31797396-31806966 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bergmann glia: 12.9;Endometrial secretory cells: 13.3;Microglia: 13.0;Mucous neck cells: 16.1;Oligodendrocytes: 26.2;Parietal cells: 15.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052805, HPA066718" Supported Enhanced Nucleoplasm NA NA 91000 "Cluster 30: Non-specific - DNA binding" "Cluster 64: Non-specific - Transcription" "Cluster 7: Non-specific - Ribosome" "Cluster 28: Non-specific - Nuclear processes" "Cluster 98: Neurons - Neurotransmission & signaling" 78 Nucleoplasm "HPA052805: , HPA066718: " "unprognostic (4.47e-2)" "unprognostic (7.54e-3)" "unprognostic (2.23e-1)" "unprognostic (1.37e-1)" "unprognostic (9.79e-2)" "unprognostic (6.39e-2)" "unprognostic (8.30e-3)" "unprognostic (1.83e-1)" "unprognostic (1.92e-1)" "unprognostic (2.01e-1)" "unprognostic (8.40e-3)" "unprognostic (6.66e-2)" "unprognostic (1.81e-2)" "validated prognostic unfavorable (3.81e-5)" "validated prognostic unfavorable (5.16e-8)" "unprognostic (2.77e-2)" "unprognostic (3.32e-2)" "unprognostic (3.30e-2)" "unprognostic (2.20e-1)" "unprognostic (3.43e-2)" "unprognostic (1.69e-1)" "unprognostic (2.60e-1)" "unprognostic (3.51e-1)" "unprognostic (4.02e-1)" "unprognostic (5.40e-3)" "unprognostic (2.26e-1)" "unprognostic (2.52e-2)" "unprognostic (7.28e-2)" "unprognostic (2.04e-1)" "unprognostic (3.53e-2)" "unprognostic (1.85e-1)" LSM3 "SMX4, USS2, YLR438C" ENSG00000170860 "LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated" P62310 3 14178817-14201122 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 459.5;Esophageal apical cells: 457.4;Esophageal basal cells: 525.9;Extravillous trophoblasts: 491.6;Late primary spermatocytes: 526.9;Migrating cytotrophoblasts: 469.7;Oocytes: 497.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044966 Approved Approved Nucleoplasm,Nucleoli NA NA 96000 "Cluster 22: Eosinophils - Transcription" "Cluster 52: Non-specific - Cellular respiration" "Cluster 31: Non-specific - Transcription" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 97: Non-specific - Cellular respiration" 78 Nucleoli Nucleoplasm "HPA044966: " "unprognostic (8.04e-2)" "potential prognostic unfavorable (4.06e-4)" "unprognostic (1.02e-2)" "unprognostic (5.11e-2)" "unprognostic (4.14e-1)" "unprognostic (1.24e-1)" "unprognostic (1.14e-1)" "unprognostic (9.16e-2)" "unprognostic (1.38e-1)" "potential prognostic unfavorable (5.23e-5)" "unprognostic (1.36e-3)" "unprognostic (2.53e-1)" "unprognostic (1.38e-1)" "unprognostic (3.67e-3)" "unprognostic (1.22e-3)" "unprognostic (1.09e-3)" "unprognostic (4.71e-2)" "unprognostic (2.91e-1)" "unprognostic (1.45e-1)" "unprognostic (1.45e-1)" "unprognostic (3.16e-2)" "unprognostic (5.94e-3)" "unprognostic (7.58e-2)" "unprognostic (3.07e-2)" "unprognostic (2.83e-2)" "unprognostic (3.63e-1)" "unprognostic (1.03e-2)" "unprognostic (1.13e-1)" "unprognostic (8.99e-2)" "unprognostic (1.78e-2)" "unprognostic (1.27e-1)" LSM4 YER112W ENSG00000130520 "LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated" Q9Y4Z0 19 18306236-18323112 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 424.9;Esophageal basal cells: 389.5;Extravillous trophoblasts: 556.3;Late spermatids: 1064.5;Migrating cytotrophoblasts: 454.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040932 Uncertain Approved Vesicles NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 27: Non-specific - Cell proliferation" 102 Vesicles "HPA040932: " "unprognostic (6.46e-2)" "unprognostic (2.08e-1)" "unprognostic (3.36e-2)" "unprognostic (1.88e-1)" "unprognostic (6.89e-2)" "unprognostic (2.08e-1)" "unprognostic (9.66e-2)" "unprognostic (1.60e-1)" "unprognostic (1.33e-2)" "unprognostic (1.11e-2)" "unprognostic (5.78e-2)" "potential prognostic unfavorable (6.52e-4)" "unprognostic (4.57e-2)" "validated prognostic unfavorable (2.49e-4)" "validated prognostic unfavorable (3.11e-11)" "potential prognostic unfavorable (9.49e-4)" "unprognostic (1.56e-2)" "unprognostic (1.50e-1)" "unprognostic (1.37e-2)" "unprognostic (2.94e-2)" "unprognostic (3.90e-1)" "unprognostic (7.76e-3)" "unprognostic (1.01e-1)" "unprognostic (1.63e-1)" "unprognostic (1.61e-1)" "unprognostic (4.82e-3)" "unprognostic (3.71e-3)" "unprognostic (1.24e-1)" "unprognostic (1.08e-1)" "unprognostic (1.94e-1)" "unprognostic (4.80e-2)" LSM5 YER146W ENSG00000106355 "LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated" Q9Y4Y9 7 32485338-32495283 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 384.8;Gastric chief cells: 442.3;Gastric progenitor cells: 860.0;Parietal cells: 440.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019054 Uncertain NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 67: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 30 "HPA019054: " "unprognostic (1.45e-3)" "unprognostic (5.57e-2)" "unprognostic (1.24e-1)" "unprognostic (8.22e-3)" "unprognostic (1.35e-2)" "unprognostic (4.67e-2)" "unprognostic (3.32e-3)" "unprognostic (3.17e-2)" "unprognostic (1.92e-3)" "unprognostic (2.72e-3)" "unprognostic (1.85e-3)" "unprognostic (3.13e-2)" "unprognostic (4.85e-2)" "validated prognostic unfavorable (4.87e-6)" "validated prognostic unfavorable (1.25e-5)" "validated prognostic unfavorable (4.83e-4)" "validated prognostic unfavorable (3.73e-4)" "unprognostic (4.92e-3)" "unprognostic (8.43e-2)" "unprognostic (4.19e-2)" "unprognostic (2.24e-2)" "unprognostic (2.13e-3)" "unprognostic (9.31e-3)" "unprognostic (2.31e-1)" "unprognostic (9.93e-2)" "unprognostic (1.53e-1)" "unprognostic (8.36e-3)" "unprognostic (2.89e-1)" "unprognostic (2.62e-1)" "unprognostic (1.55e-2)" "unprognostic (1.85e-1)" LSM6 YDR378C ENSG00000164167 "LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated" P62312 4 146175703-146200000 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, rRNA processing, tRNA processing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 224.6;Extravillous trophoblasts: 219.6;Gastric progenitor cells: 216.6;Oocytes: 308.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045079 Approved Approved "Actin filaments" NA NA 13000 "Cluster 33: Non-specific - ATP binding" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 25: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 88 "Actin filaments" "HPA045079: " "unprognostic (1.77e-1)" "unprognostic (1.07e-1)" "unprognostic (2.37e-1)" "unprognostic (2.19e-1)" "unprognostic (4.16e-2)" "unprognostic (1.77e-1)" "unprognostic (2.52e-2)" "unprognostic (1.09e-1)" "unprognostic (1.96e-1)" "unprognostic (1.61e-2)" "potential prognostic favorable (6.52e-6)" "unprognostic (6.63e-3)" "unprognostic (4.15e-2)" "unprognostic (5.13e-3)" "unprognostic (3.21e-2)" "unprognostic (1.92e-2)" "unprognostic (2.06e-1)" "unprognostic (1.41e-1)" "unprognostic (3.91e-1)" "unprognostic (2.75e-1)" "unprognostic (4.27e-1)" "unprognostic (3.15e-2)" "unprognostic (3.72e-2)" "unprognostic (9.77e-2)" "unprognostic (1.39e-1)" "unprognostic (2.40e-2)" "unprognostic (7.28e-2)" "unprognostic (2.31e-1)" "unprognostic (2.00e-1)" "unprognostic (4.95e-2)" "unprognostic (7.48e-2)" LSM7 YNL147W ENSG00000130332 "LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated" Q9UK45 19 2321520-2328611 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal basal cells: 491.0;Migrating cytotrophoblasts: 472.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041850 Uncertain Approved "Nucleoli fibrillar center" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 81 "Nucleoli fibrillar center" "HPA041850: " "unprognostic (2.11e-1)" "unprognostic (6.98e-2)" "unprognostic (4.35e-1)" "potential prognostic favorable (5.30e-4)" "unprognostic (6.02e-2)" "unprognostic (1.98e-3)" "unprognostic (2.38e-2)" "unprognostic (3.14e-1)" "unprognostic (5.00e-2)" "unprognostic (1.59e-1)" "potential prognostic unfavorable (8.43e-4)" "unprognostic (1.74e-2)" "unprognostic (2.20e-2)" "potential prognostic unfavorable (5.60e-5)" "unprognostic (1.36e-3)" "unprognostic (2.56e-1)" "unprognostic (4.97e-3)" "unprognostic (3.19e-3)" "unprognostic (5.10e-2)" "unprognostic (5.10e-2)" "unprognostic (3.84e-2)" "unprognostic (2.01e-2)" "unprognostic (2.89e-1)" "unprognostic (2.06e-2)" "unprognostic (1.40e-1)" "unprognostic (9.89e-2)" "unprognostic (7.76e-2)" "unprognostic (1.10e-3)" "unprognostic (1.45e-1)" "unprognostic (2.05e-1)" "unprognostic (1.22e-2)" LSM8 YJR022W ENSG00000128534 "LSM8 homolog, U6 small nuclear RNA associated" O95777 7 118184144-118204035 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020116 Uncertain Approved Nucleoplasm,Vesicles NA NA 47000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 49: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 39: Non-specific - Transcription" "Cluster 15: Non-specific - Protein processing" 43 "Nucleoplasm, Vesicles" "HPA020116: " "unprognostic (1.21e-1)" "unprognostic (2.09e-1)" "unprognostic (4.33e-2)" "unprognostic (7.18e-2)" "unprognostic (3.07e-1)" "unprognostic (5.30e-3)" "unprognostic (1.31e-1)" "unprognostic (1.09e-1)" "potential prognostic unfavorable (4.38e-5)" "unprognostic (1.03e-2)" "unprognostic (2.99e-1)" "unprognostic (5.93e-3)" "potential prognostic unfavorable (2.54e-4)" "unprognostic (1.48e-2)" "unprognostic (1.14e-2)" "unprognostic (6.01e-2)" "unprognostic (6.02e-2)" "unprognostic (1.34e-1)" "unprognostic (1.80e-2)" "unprognostic (1.91e-3)" "unprognostic (2.06e-1)" "unprognostic (5.87e-2)" "unprognostic (5.41e-2)" "unprognostic (6.42e-2)" "unprognostic (2.13e-1)" "unprognostic (2.18e-1)" "unprognostic (2.39e-1)" "unprognostic (1.52e-1)" "unprognostic (5.80e-2)" LSMEM1 "C7orf53, FLJ39575" ENSG00000181016 "Leucine rich single-pass membrane protein 1" Q8N8F7 7 112480853-112491062 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "skeletal muscle: 76.4" "Cell type enhanced" "Detected in some" "Astrocytes: 8.3;Brain excitatory neurons: 8.1;Brain inhibitory neurons: 6.4;Choroid plexus epithelial cells: 9.9;Early spermatids: 18.3;Late spermatids: 38.7;Loop of henle epithelial cells: 7.7;Other brain neurons: 8.4;Podocytes: 5.9;Proximal tubule cells: 9.8;Renal connecting tubule cells: 6.6" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "cervical cancer: 1.4" "Skeletal muscle - Skeletal myocytes, Testis - Late spermatids" "Group enriched" "Detected in many" 4 "amygdala: 1.4;basal ganglia: 1.0;cerebellum: 4.0;olfactory bulb: 3.3" "Low region specificity" "Detected in all" "HPA013753, HPA047988" Uncertain Supported Vesicles,Cytosol NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 56: Non-specific - Sensory perception" "Cluster 102: Non-specific - Mixed function" 5 Cytosol Vesicles "HPA013753: , HPA047988: " "unprognostic (2.03e-2)" "unprognostic (2.46e-2)" "unprognostic (1.98e-3)" LSMEM2 "C3orf45, FLJ38608" ENSG00000179564 "Leucine rich single-pass membrane protein 2" Q8N112 3 50279087-50288114 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 22.3;skeletal muscle: 15.1" "Cell type enriched" "Detected in many" 8 "Late spermatids: 500.6" "Cell type enhanced" "Detected in some" "oligodendrocyte: 5.5;vascular associated smooth muscle cell: 4.2" "Group enriched" "Detected in some" 13 "Prostate Adenocarcinoma (TCGA): 12.3;Uterine Corpus Endometrial Carcinoma (TCGA): 14.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Smooth muscle cells, Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA079523 Approved "Plasma membrane" NA NA "Cluster 41: Striated muscle - Muscle contraction" "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 26 "Plasma membrane" "HPA079523: " "unprognostic (4.95e-3)" "unprognostic (1.03e-3)" "unprognostic (6.63e-2)" "unprognostic (2.20e-1)" "unprognostic (7.57e-2)" "unprognostic (2.35e-1)" "unprognostic (2.66e-2)" LSP1 WP34 ENSG00000130592 "Lymphocyte specific protein 1" P33241 11 1850904-1892267 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 218.5;lymphoid tissue: 251.1" "Cell type enhanced" "Detected in some" "B-cells: 20.4;cDC: 28.1;Innate lymphoid cells: 13.8;monocytes: 30.7;Neutrophil progenitors: 16.4;Neutrophils: 79.2;NK-cells: 32.7;pDCs: 13.7;Plasma cells: 26.2;T-cells: 20.4;Thymocytes: 22.0" "Cell type enriched" "Detected in some" 9 "leukocyte: 143.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 35 "Leukemia: 97.4;lymphoma: 355.2;Myeloma: 161.8" "Adipose subcutaneous - Adipose progenitor cells, Minor Salivary Gland - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Keratinocyte (other), Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017781, HPA019693" Enhanced NA NA 780000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 59: Leukemia - T-cell receptor" "Cluster 102: Non-specific - Mixed function" 2 "CAB017781: , HPA019693: " "unprognostic (8.03e-3)" "unprognostic (3.44e-3)" "unprognostic (3.32e-3)" "unprognostic (2.97e-3)" "unprognostic (1.07e-2)" "unprognostic (2.05e-1)" "potential prognostic unfavorable (2.77e-4)" "unprognostic (5.68e-2)" "unprognostic (3.05e-3)" "unprognostic (7.57e-2)" "unprognostic (6.15e-2)" "unprognostic (1.20e-1)" "unprognostic (3.18e-1)" "unprognostic (8.56e-2)" "unprognostic (5.89e-2)" "unprognostic (1.59e-2)" "unprognostic (9.27e-3)" "unprognostic (4.87e-2)" "unprognostic (2.35e-1)" "unprognostic (4.11e-2)" "unprognostic (1.79e-1)" "unprognostic (4.95e-2)" "unprognostic (7.08e-2)" "unprognostic (5.94e-2)" "unprognostic (1.36e-1)" "unprognostic (9.27e-2)" "unprognostic (9.99e-3)" "unprognostic (2.82e-1)" "unprognostic (6.40e-3)" "unprognostic (5.29e-2)" "unprognostic (3.63e-2)" LSR "ILDR3, LISCH7" ENSG00000105699 "Lipolysis stimulated lipoprotein receptor" Q86X29 19 35248330-35267964 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 138.5" "Cell type enhanced" "Detected in many" "Colonocytes: 294.5;Cytotrophoblasts: 246.0;Esophageal apical cells: 228.9;Migrating cytotrophoblasts: 222.8;Retinal pigment epithelial cells: 362.4;Syncytiotrophoblasts: 286.3;Urothelial cells: 228.4" "Cell type enriched" "Detected in many" 7 "endothelial cell: 195.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Lung - Alveolar cells type 2, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007270, HPA075309" Approved Enhanced "Plasma membrane,Cell Junctions" NA NA 3500000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 60: Stomach - Digestion" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 17 "Plasma membrane, Cell Junctions" "HPA007270: , HPA075309: " "unprognostic (1.42e-2)" "unprognostic (1.36e-2)" "unprognostic (1.42e-1)" "unprognostic (2.03e-3)" "unprognostic (5.78e-3)" "unprognostic (4.23e-2)" "unprognostic (1.42e-1)" "unprognostic (1.19e-1)" "unprognostic (3.05e-2)" "unprognostic (3.24e-1)" "unprognostic (6.72e-3)" "unprognostic (1.51e-1)" "unprognostic (1.15e-1)" "unprognostic (1.58e-1)" "unprognostic (1.59e-1)" "unprognostic (6.32e-3)" "unprognostic (7.38e-3)" "unprognostic (1.92e-1)" "unprognostic (2.39e-1)" "unprognostic (5.11e-3)" "unprognostic (7.56e-2)" "unprognostic (6.36e-3)" "unprognostic (2.88e-2)" "unprognostic (7.32e-2)" "unprognostic (4.39e-2)" "unprognostic (1.20e-1)" "unprognostic (1.68e-1)" "unprognostic (1.29e-1)" "unprognostic (2.83e-1)" "unprognostic (1.01e-1)" "unprognostic (3.08e-1)" LSS OSC ENSG00000160285 "Lanosterol synthase" P48449 21 46188141-46228824 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Isomerase "Cataract, Disease variant, Hypotrichosis, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 74.5;Bergmann glia: 59.2;Brain inhibitory neurons: 42.1;Oligodendrocytes: 190.0;Other brain neurons: 60.5;Retinal ganglion cells: 154.5" "Cell type enhanced" "Detected in all" "oligodendrocyte: 270.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032060, HPA032062, CAB034116" Supported NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 70: Non-specific - Protein processing" "Cluster 49: Hindbrain - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 80: Oligodendrocytes - Myelination" 17 "CAB034116: , HPA032060: , HPA032062: " "unprognostic (7.31e-2)" "unprognostic (1.16e-2)" "unprognostic (3.01e-1)" "unprognostic (1.77e-2)" "unprognostic (2.65e-1)" "unprognostic (4.47e-2)" "unprognostic (3.99e-2)" "unprognostic (3.22e-1)" "unprognostic (9.95e-2)" "unprognostic (1.36e-1)" "potential prognostic favorable (8.38e-6)" "unprognostic (2.53e-1)" "unprognostic (1.48e-1)" "unprognostic (8.92e-2)" "unprognostic (4.03e-2)" "unprognostic (3.44e-1)" "unprognostic (4.55e-1)" "unprognostic (2.47e-2)" "unprognostic (7.99e-2)" "unprognostic (4.80e-3)" "unprognostic (2.01e-1)" "unprognostic (8.58e-2)" "unprognostic (1.90e-1)" "unprognostic (3.02e-2)" "unprognostic (3.48e-2)" "unprognostic (3.13e-2)" "unprognostic (3.71e-1)" "unprognostic (1.95e-2)" "unprognostic (1.71e-1)" "unprognostic (1.34e-1)" "unprognostic (1.23e-1)" LST1 "B144, D6S49E, LST-1" ENSG00000204482 "Leukocyte specific transcript 1" O00453 6 31586124-31588909 "Essential proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell shape, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 94.4;lymphoid tissue: 180.8" "Cell type enhanced" "Detected in some" "cDC: 432.6;Hofbauer cells: 210.4;Innate lymphoid cells: 105.7;Kupffer cells: 966.5;Macrophages: 204.2;Megakaryocytes: 105.1;Microglia: 150.9;Monocyte progenitors: 134.4;monocytes: 476.4;Neutrophil progenitors: 120.2;Neutrophils: 550.2" "Group enriched" "Detected in some" 70 "central nervous system macrophage: 169.7;leukocyte: 72.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 1767.7" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in some" 17 "Leukemia: 45.7" "Adipose visceral - Macrophages, Adrenal gland - Macrophages, Liver - Kupffer cells, Minor Salivary Gland - Macrophages, Skeletal muscle - Macrophages, Skin - Langerhans cells, Spleen - Macrophages, Stomach - Macrophages" "Low region specificity" "Detected in all" HPA079451 Supported "Plasma membrane,Cytosol" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" "Plasma membrane, Cytosol" "HPA079451: " "unprognostic (1.49e-2)" "unprognostic (1.76e-3)" "unprognostic (4.62e-3)" "unprognostic (3.89e-3)" "unprognostic (1.97e-1)" "unprognostic (7.29e-2)" "unprognostic (1.87e-1)" "unprognostic (3.94e-2)" "unprognostic (1.20e-2)" "unprognostic (1.45e-1)" "unprognostic (9.16e-3)" "unprognostic (1.74e-1)" "unprognostic (2.87e-2)" "unprognostic (9.19e-2)" "unprognostic (9.82e-2)" "unprognostic (5.09e-3)" "unprognostic (1.16e-1)" "unprognostic (1.94e-1)" "unprognostic (2.23e-1)" "unprognostic (1.79e-1)" "unprognostic (1.82e-1)" "unprognostic (4.19e-2)" "unprognostic (3.15e-2)" "unprognostic (6.89e-2)" "unprognostic (2.58e-1)" "potential prognostic favorable (3.06e-4)" "unprognostic (1.94e-1)" "unprognostic (1.45e-1)" "unprognostic (1.22e-1)" "unprognostic (1.97e-1)" "unprognostic (2.58e-1)" LTA "LT, TNFB, TNFSF1" ENSG00000226979 "Lymphotoxin alpha" P01374 6 31572054-31574324 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted secreted proteins" Cytokine "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 1.8;lymphoid tissue: 5.4;testis: 4.1" "Cell type enriched" "Detected in single" 4 "Innate lymphoid cells: 2.4" "Cell type enriched" "Detected in single" 12 "leukocyte: 2.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 9 "lymphoma: 17.1" "Adipose visceral - T-cells, Breast - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA007729 Uncertain "Secreted to blood" Cytokine NA NA 8150 "Cluster 39: Testis - Nuclear processes" "Cluster 50: Lymphoma - Unknown function" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 19 "HPA007729: " "unprognostic (5.13e-3)" LTA4H ENSG00000111144 "Leukotriene A4 hydrolase" P09960 12 96000753-96043520 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Leukotriene biosynthesis, Lipid metabolism" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 211.3;Esophageal apical cells: 312.7;Esophageal suprabasal cells: 224.6;monocytes: 284.7;Neutrophil progenitors: 497.5;Neutrophils: 334.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008399, CAB015221, HPA017017" Supported Supported Nucleoplasm,Cytosol NA NA 62000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 25: Non-specific - Ribosome" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 4 Cytosol Nucleoplasm "CAB015221: , HPA008399: , HPA017017: " "unprognostic (2.36e-1)" "unprognostic (1.02e-2)" "unprognostic (2.09e-1)" "unprognostic (6.99e-2)" "unprognostic (4.88e-2)" "unprognostic (1.50e-1)" "unprognostic (1.21e-1)" "unprognostic (1.08e-1)" "unprognostic (2.93e-3)" "unprognostic (1.38e-1)" "potential prognostic favorable (7.25e-8)" "unprognostic (3.55e-3)" "unprognostic (7.33e-2)" "unprognostic (2.28e-3)" "unprognostic (1.77e-2)" "unprognostic (3.00e-2)" "unprognostic (2.48e-1)" "unprognostic (1.01e-1)" "unprognostic (3.38e-1)" "unprognostic (8.74e-3)" "unprognostic (5.78e-3)" "unprognostic (1.48e-1)" "unprognostic (4.94e-2)" "unprognostic (6.81e-2)" "unprognostic (4.58e-2)" "unprognostic (9.51e-2)" "unprognostic (2.04e-2)" "unprognostic (4.27e-1)" "unprognostic (5.45e-2)" "unprognostic (1.18e-2)" "unprognostic (3.17e-3)" LTB "p33, TNFC, TNFSF3" ENSG00000227507 "Lymphotoxin beta" Q06643 6 31580525-31582522 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "intestine: 61.7;lymphoid tissue: 220.1" "Cell type enhanced" "Detected in some" "B-cells: 34.8;Innate lymphoid cells: 19.2;Loop of henle epithelial cells: 3.3;Neutrophils: 3.7;Papillary tip epithelial cells: 5.5;pDCs: 11.9;T-cells: 11.0" "Cell type enriched" "Detected in many" 31 "leukocyte: 116.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 30.2;lymphoma: 62.3" "Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Liver - T-cells, Minor Salivary Gland - T-cells, Pituitary gland - T-cells, Skin - Langerhans cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA048884 Approved Approved Centrosome NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 102: Non-specific - Mixed function" 1 Centrosome "HPA048884: " "unprognostic (5.66e-2)" "unprognostic (4.21e-3)" "potential prognostic favorable (1.22e-4)" "unprognostic (1.62e-3)" "unprognostic (6.53e-2)" "unprognostic (2.86e-2)" "unprognostic (1.48e-2)" "unprognostic (1.13e-3)" "unprognostic (8.93e-2)" "unprognostic (7.65e-3)" "unprognostic (4.13e-1)" "unprognostic (1.54e-1)" "unprognostic (3.02e-2)" "unprognostic (1.01e-1)" "unprognostic (3.56e-3)" "unprognostic (3.71e-1)" "unprognostic (2.02e-1)" "unprognostic (1.76e-1)" "unprognostic (2.43e-1)" "unprognostic (1.82e-1)" "unprognostic (2.03e-2)" "unprognostic (1.23e-1)" "unprognostic (1.95e-1)" "unprognostic (1.39e-1)" "unprognostic (9.06e-2)" "unprognostic (3.28e-3)" "unprognostic (1.32e-1)" "unprognostic (5.05e-2)" "unprognostic (6.92e-2)" "unprognostic (9.25e-2)" LTB4R "BLTR, CMKRL1, GPR16, LTB4R1, P2RY7, P2Y7" ENSG00000213903 "Leukotriene B4 receptor" Q15722 14 24311450-24318036 "Essential proteins, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 99.2;skin 1: 106.0" "Cell type enhanced" "Detected in some" "B-cells: 2.4;Brain excitatory neurons: 2.0;Brain inhibitory neurons: 2.1;Distal convoluted tubule cells: 3.9;Ependymal cells: 6.0;Loop of henle epithelial cells: 2.8;Microglia: 5.2;NK-cells: 2.0;Papillary tip epithelial cells: 6.7;Podocytes: 3.6;Proximal tubule cells: 8.3;Renal collecting duct intercalated cells: 4.9;Renal collecting duct principal cells: 2.7;Renal connecting tubule cells: 3.8" "Cell type enhanced" "Detected in many" "leukocyte: 21.5" "Cancer enhanced" "Detected in all" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 23.7;Head and Neck Squamous Cell Carcinoma (TCGA): 26.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 100.8" "Group enriched" "Detected in many" 6 "granulocytes: 100.8;monocytes: 38.5" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" HPA003873 Approved NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 58: Skin - Keratinization" "Cluster 6: Non-specific - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 102: Non-specific - Mixed function" 1 "HPA003873: " "unprognostic (2.63e-1)" "unprognostic (1.06e-1)" "unprognostic (2.27e-2)" "unprognostic (2.63e-1)" "unprognostic (5.28e-2)" "unprognostic (6.86e-2)" "unprognostic (3.79e-2)" "unprognostic (3.44e-2)" "unprognostic (8.70e-3)" "unprognostic (1.77e-1)" "potential prognostic unfavorable (1.04e-6)" "unprognostic (1.21e-1)" "unprognostic (3.11e-3)" "unprognostic (3.93e-2)" "unprognostic (7.21e-2)" "unprognostic (5.99e-3)" "unprognostic (2.69e-1)" "unprognostic (1.37e-1)" "unprognostic (1.26e-1)" "unprognostic (9.18e-2)" "unprognostic (7.59e-2)" "potential prognostic favorable (5.86e-4)" "unprognostic (2.47e-3)" "unprognostic (2.38e-1)" "unprognostic (1.90e-1)" "unprognostic (1.08e-2)" "unprognostic (2.14e-1)" "unprognostic (3.94e-2)" "unprognostic (1.96e-1)" "unprognostic (1.10e-1)" "unprognostic (1.44e-1)" LTB4R2 "BLT2, BLTR2, JULF2, NOP9" ENSG00000213906 "Leukotriene B4 receptor 2" Q9NPC1 14 24305734-24312053 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 36.1;skin 1: 44.9" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 11.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB022689, HPA029680, HPA072921" Uncertain Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 58: Skin - Keratinization" "Cluster 6: Non-specific - Immune response" "Cluster 56: Non-specific - Sensory perception" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 1 "Plasma membrane" Nucleoplasm "CAB022689: , HPA029680: , HPA072921: " "unprognostic (4.50e-2)" "unprognostic (1.18e-2)" "unprognostic (1.46e-1)" "unprognostic (2.15e-1)" "unprognostic (5.72e-2)" "unprognostic (8.91e-3)" "unprognostic (1.92e-1)" "unprognostic (4.56e-2)" "unprognostic (1.12e-1)" "unprognostic (1.39e-1)" "unprognostic (1.75e-2)" "unprognostic (1.83e-1)" "unprognostic (1.06e-1)" "unprognostic (8.49e-2)" "unprognostic (2.82e-1)" "unprognostic (1.13e-1)" "unprognostic (2.09e-1)" LTBP1 ENSG00000049323 "Latent transforming growth factor beta binding protein 1" Q14766 2 32946953-33399509 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Growth factor binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 382.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 495.6;Erythrocyte progenitors: 422.9;Fibroblasts: 388.7;Hepatic stellate cells: 445.4;Megakaryocyte progenitors: 1987.3;Pituitary stem cells: 535.5;Platelets: 536.8;Vascular smooth muscle cells: 627.4" "Cell type enhanced" "Detected in all" "mammillary body: 645.5;vascular associated smooth muscle cell: 1013.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "basophil: 3.2" "Lineage enriched" "Detected in single" 14 "granulocytes: 3.2" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Adrenal gland - Fibroblasts, Breast - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Pituitary gland - Fibroblasts, Prostate - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" CAB025428 Approved "Secreted to extracellular matrix" Other NA NA 160000000 "Cluster 20: Non-specific - DNA binding" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 4 "CAB025428: " "unprognostic (2.23e-1)" "unprognostic (5.73e-2)" "unprognostic (3.19e-2)" "unprognostic (2.62e-2)" "unprognostic (1.28e-2)" "unprognostic (6.37e-2)" "unprognostic (7.92e-3)" "unprognostic (1.22e-1)" "unprognostic (1.62e-1)" "unprognostic (6.88e-3)" "unprognostic (1.67e-1)" "unprognostic (3.20e-1)" "potential prognostic unfavorable (9.75e-4)" "potential prognostic unfavorable (6.99e-4)" "unprognostic (1.14e-1)" "unprognostic (6.21e-2)" "unprognostic (4.61e-2)" "unprognostic (4.30e-1)" "unprognostic (6.91e-2)" "unprognostic (1.68e-1)" "unprognostic (1.19e-1)" "unprognostic (1.46e-2)" "unprognostic (2.06e-1)" "unprognostic (1.74e-1)" "unprognostic (5.67e-2)" "unprognostic (1.02e-2)" "unprognostic (1.91e-2)" "unprognostic (1.94e-2)" "unprognostic (1.93e-1)" "unprognostic (2.13e-1)" "unprognostic (1.69e-1)" LTBP2 "C14orf141, LTBP3" ENSG00000119681 "Latent transforming growth factor beta binding protein 2" Q14767 14 74498183-74612378 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding, Heparin-binding" "Disease variant, Dwarfism, Glaucoma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "blood vessel: 337.5" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 57.7;Breast myoepithelial cells: 181.7;Fibro-adipogenic progenitors: 212.3;Fibroblasts: 194.1;Hepatic stellate cells: 83.9;Peritubular myoid cells: 99.1;Pituicytes/FSCs: 51.7;Respiratory ionocytes: 81.3;Salivary basal cells: 61.3;Salivary ionocytes: 83.6;Salivary myoepithelial cells: 86.9" "Cell type enriched" "Detected in many" 7 "fibroblast: 154.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Colon - Fibroblasts, Kidney - Fibroblasts, Stomach - Fibroblasts" "Group enriched" "Detected in some" 10 "cerebellum: 5.3;olfactory bulb: 2.4" "Region enhanced" "Detected in all" "olfactory bulb: 20.5" HPA003415 Supported "Secreted to extracellular matrix" Other NA NA 16000000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 8: Immune cells - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 1 "HPA003415: " "unprognostic (3.64e-1)" "unprognostic (1.79e-1)" "unprognostic (2.11e-1)" "unprognostic (3.74e-3)" "unprognostic (2.95e-2)" "unprognostic (1.96e-2)" "unprognostic (5.23e-3)" "unprognostic (3.29e-3)" "unprognostic (3.83e-1)" "unprognostic (2.08e-1)" "unprognostic (2.48e-2)" "unprognostic (7.88e-2)" "potential prognostic unfavorable (1.53e-5)" "unprognostic (4.05e-1)" "unprognostic (5.30e-3)" "unprognostic (1.54e-1)" "unprognostic (1.54e-1)" "unprognostic (1.23e-2)" "unprognostic (1.94e-1)" "unprognostic (2.66e-2)" "unprognostic (3.76e-3)" "unprognostic (2.53e-2)" "unprognostic (9.24e-2)" "unprognostic (3.81e-1)" "unprognostic (1.97e-1)" "potential prognostic favorable (6.75e-4)" "unprognostic (2.31e-1)" "unprognostic (4.67e-3)" "unprognostic (1.97e-1)" "unprognostic (2.24e-1)" "unprognostic (6.40e-2)" LTBP3 LTBP2 ENSG00000168056 "Latent transforming growth factor beta binding protein 3" Q9NS15 11 65538559-65558930 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding" "Amelogenesis imperfecta, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 226.7" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 55.7;naive B-cell: 44.7" "Lineage enriched" "Detected in all" 5 "B-cells: 55.7" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" Other NA NA 17000000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 74: Non-specific - Signal transduction" "Cluster 39: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 108: Fibroblasts - ECM organization" "unprognostic (1.02e-2)" "unprognostic (1.74e-1)" "unprognostic (4.17e-2)" "unprognostic (1.01e-2)" "unprognostic (6.08e-3)" "unprognostic (6.20e-3)" "unprognostic (2.38e-1)" "unprognostic (2.58e-1)" "unprognostic (4.10e-1)" "unprognostic (1.50e-1)" "unprognostic (1.06e-1)" "unprognostic (3.07e-2)" "unprognostic (1.31e-1)" "unprognostic (4.32e-2)" "unprognostic (3.38e-1)" "unprognostic (3.92e-1)" "unprognostic (1.73e-1)" "unprognostic (6.64e-2)" "unprognostic (2.34e-1)" "unprognostic (2.75e-2)" "unprognostic (1.06e-1)" "unprognostic (4.01e-2)" "unprognostic (2.65e-2)" "unprognostic (1.27e-1)" "unprognostic (7.83e-2)" "unprognostic (1.35e-2)" "unprognostic (1.38e-1)" "unprognostic (1.11e-2)" "unprognostic (1.09e-1)" "unprognostic (2.63e-2)" "unprognostic (8.97e-2)" LTBP4 "FLJ46318, FLJ90018, LTBP-4, LTBP-4L" ENSG00000090006 "Latent transforming growth factor beta binding protein 4" Q8N2S1 19 40592883-40629818 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 548.8" "Cell type enhanced" "Detected in many" "Fibro-adipogenic progenitors: 188.0;Fibroblasts: 257.6;Leydig cells: 1219.9;Ovarian stromal cells: 322.8;Peritubular myoid cells: 760.4;Schwann cells: 279.7" "Cell type enhanced" "Detected in many" "fibroblast: 123.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblasts_1, Minor Salivary Gland - Fibroblasts, Pancreas - Fibroblasts, Pituitary gland - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB015194 Enhanced "Secreted to extracellular matrix" Other NA NA 5400000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 24: Neurons - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 94: Gonadal somatic cells - Mixed function" 6 "CAB015194: " "unprognostic (5.15e-3)" "unprognostic (2.65e-2)" "unprognostic (1.65e-2)" "unprognostic (1.21e-1)" "unprognostic (9.50e-2)" "unprognostic (8.10e-2)" "unprognostic (2.27e-3)" "unprognostic (6.35e-3)" "unprognostic (9.38e-3)" "unprognostic (2.58e-2)" "unprognostic (3.95e-1)" "unprognostic (2.66e-1)" "unprognostic (9.34e-2)" "unprognostic (1.06e-1)" "unprognostic (1.04e-3)" "unprognostic (4.15e-2)" "unprognostic (2.92e-1)" "unprognostic (1.90e-1)" "unprognostic (4.83e-2)" "unprognostic (2.75e-2)" "unprognostic (2.65e-1)" "unprognostic (9.91e-2)" "unprognostic (6.93e-2)" "unprognostic (5.52e-2)" "unprognostic (3.59e-1)" "unprognostic (2.91e-1)" "unprognostic (4.01e-2)" "unprognostic (1.54e-2)" "unprognostic (3.10e-1)" "unprognostic (5.20e-2)" "unprognostic (1.42e-1)" LTBR "D12S370, TNF-R-III, TNFCR, TNFR-RP, TNFR2-RP, TNFRSF3" ENSG00000111321 "Lymphotoxin beta receptor" P36941 12 6375045-6391571 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Host-virus interaction" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 151.2;Esophageal apical cells: 192.9" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 46.7;fibroblast: 32.7;pericyte: 39.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 71.4;intermediate monocyte: 66.4;myeloid DC: 49.9;neutrophil: 45.2;non-classical monocyte: 50.3" "Group enriched" "Detected in many" 36 "dendritic cells: 49.9;granulocytes: 45.2;monocytes: 71.4" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026202, HPA061617" Uncertain Supported "Golgi apparatus" NA Yes 13000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 17: Non-specific - RNA processing" 22 "Golgi apparatus" "CAB026202: , HPA061617: " "unprognostic (2.52e-2)" "unprognostic (1.56e-2)" "unprognostic (3.96e-2)" "unprognostic (1.37e-2)" "unprognostic (1.15e-1)" "unprognostic (5.26e-2)" "unprognostic (1.98e-2)" "unprognostic (4.66e-2)" "unprognostic (1.68e-3)" "unprognostic (2.01e-2)" "unprognostic (3.60e-2)" "unprognostic (2.10e-3)" "unprognostic (1.19e-1)" "validated prognostic unfavorable (7.58e-4)" "validated prognostic unfavorable (7.68e-4)" "unprognostic (3.59e-3)" "unprognostic (3.10e-3)" "unprognostic (1.43e-1)" "unprognostic (5.14e-2)" "unprognostic (1.44e-1)" "unprognostic (1.73e-1)" "unprognostic (4.82e-3)" "unprognostic (1.64e-2)" "unprognostic (1.31e-1)" "unprognostic (8.61e-3)" "unprognostic (2.30e-2)" "unprognostic (3.76e-2)" "unprognostic (1.39e-2)" "unprognostic (1.14e-1)" "unprognostic (3.07e-1)" "unprognostic (7.61e-2)" LTC4S MGC33147 ENSG00000213316 "Leukotriene C4 synthase" Q16873 5 179793980-179796647 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Leukotriene biosynthesis, Lipid biosynthesis, Lipid metabolism" "Lyase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fallopian secretory cells: 77.4;Hepatic stellate cells: 51.6;Hofbauer cells: 70.9;Lymphatic endothelial cells: 50.6;Macrophages: 43.8;Mast cells: 284.8;Megakaryocytes: 61.8;Microglia: 165.2" "Cell type enriched" "Detected in all" 6 "central nervous system macrophage: 186.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 20.4;eosinophil: 63.3" "Lineage enriched" "Detected in many" 7 "granulocytes: 63.3" "Cancer enriched" "Detected in single" 11 "Leukemia: 5.6" "Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" HPA044688 Approved "Nucleoplasm,Endoplasmic reticulum,Cytosol" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 74: Non-specific - Signal transduction" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 58: Mast cells - Allergic inflammatory responses" 9 Nucleoplasm "Endoplasmic reticulum, Cytosol" "HPA044688: " "unprognostic (1.67e-1)" "unprognostic (3.28e-1)" "unprognostic (3.31e-2)" "unprognostic (1.31e-1)" "unprognostic (1.00e-1)" "unprognostic (3.25e-3)" "unprognostic (2.67e-1)" "unprognostic (5.59e-2)" "unprognostic (5.87e-3)" "unprognostic (3.13e-3)" "unprognostic (1.72e-2)" "unprognostic (1.37e-1)" "validated prognostic favorable (5.27e-4)" "validated prognostic favorable (1.90e-4)" "unprognostic (1.42e-1)" "unprognostic (4.67e-3)" "unprognostic (8.30e-2)" LTF HLF2 ENSG00000012223 Lactotransferrin P02788 3 46435645-46485234 "Cancer-related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Ion transport, Iron transport, Osteogenesis, Transcription, Transcription regulation, Transport" "Antibiotic, Antimicrobial, DNA-binding, Heparin-binding, Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 4021.0;salivary gland: 1063.0" "Cell type enhanced" "Detected in many" "Breast lactating cells: 12229.9;Lacrimal acinar cells: 29240.1;Neutrophil progenitors: 6129.2;Salivary acinar cells: 3274.4;Submucosal glandular cells: 3406.3" "Group enriched" "Detected in some" 9 "astrocyte: 5.9;endothelial cell: 6.4" "Cancer enhanced" "Detected in all" "Breast Invasive Carcinoma (TCGA): 588.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 23 "neutrophil: 5.4;non-classical monocyte: 17.0" "Group enriched" "Detected in many" 23 "granulocytes: 5.4;monocytes: 17.0" "Cancer enhanced" "Detected in some" "Myeloma: 2.9" "Kidney - Macrophages, Lung - Neutrophils_1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB008646, CAB016201, HPA057177, HPA059976" Enhanced "Secreted to blood" Transport NA NA 470000000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 15: Bone marrow - Innate immune response" "Cluster 46: Brainstem - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 20 "CAB008646: , CAB016201: , HPA057177: , HPA059976: " "unprognostic (9.72e-3)" "unprognostic (1.75e-3)" "unprognostic (1.81e-1)" "unprognostic (6.80e-2)" "unprognostic (1.61e-1)" "unprognostic (2.57e-1)" "unprognostic (4.09e-3)" "unprognostic (5.31e-3)" "unprognostic (2.63e-2)" "unprognostic (3.63e-1)" "potential prognostic favorable (2.41e-4)" "unprognostic (2.05e-2)" "unprognostic (4.41e-2)" "unprognostic (1.04e-2)" "potential prognostic favorable (6.96e-4)" "unprognostic (2.10e-1)" "unprognostic (8.79e-2)" "unprognostic (2.90e-2)" "unprognostic (3.64e-2)" "unprognostic (1.38e-1)" "unprognostic (2.44e-2)" "unprognostic (3.72e-1)" "unprognostic (5.09e-2)" "unprognostic (1.29e-1)" "unprognostic (1.24e-1)" "unprognostic (4.97e-2)" "unprognostic (3.18e-1)" "unprognostic (1.08e-2)" "unprognostic (3.12e-1)" "unprognostic (2.62e-1)" "unprognostic (3.14e-1)" LTK TYK1 ENSG00000062524 "Leukocyte receptor tyrosine kinase" P29376 15 41503637-41513887 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 12.4;lung: 14.3;salivary gland: 11.1" "Cell type enhanced" "Detected in some" "Colonocytes: 22.4;Conjunctival goblet cells: 18.4;Enterocytes: 15.3;Foveolar cells: 12.8;Goblet cells: 11.4;Megakaryocyte progenitors: 7.8;Oocytes: 9.2;pDCs: 31.4;Plasma cells: 7.9;Respiratory ciliated cells: 7.7;Salivary duct cells: 23.0;Thymic myoid cells: 8.2" "Cell type enhanced" "Detected in some" "upper-layer intratelencephalic: 6.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 5 "MAIT T-cell: 5.7;plasmacytoid DC: 5.0" "Group enriched" "Detected in many" 10 "dendritic cells: 5.0;T-cells: 5.7" "Low cancer specificity" "Detected in many" "Liver - Sinusoid Endothelial cells, Prostate - T-cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" HPA059545 Approved Vesicles NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 53: Neurons - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 37 Vesicles "HPA059545: " "unprognostic (1.94e-1)" "unprognostic (5.28e-3)" "unprognostic (1.20e-1)" "unprognostic (2.28e-2)" "unprognostic (7.92e-2)" "unprognostic (2.75e-1)" "unprognostic (8.84e-2)" "unprognostic (7.55e-2)" "unprognostic (2.10e-1)" "unprognostic (5.39e-2)" "unprognostic (7.01e-2)" "unprognostic (4.46e-2)" "unprognostic (8.15e-2)" "unprognostic (1.26e-1)" "unprognostic (4.12e-2)" "unprognostic (4.79e-2)" "unprognostic (7.77e-2)" "unprognostic (1.38e-1)" "unprognostic (1.54e-1)" LTN1 "C21orf10, C21orf98, FLJ11053, KIAA0714, LISTERIN, RNF160, ZNF294" ENSG00000198862 "Listerin E3 ubiquitin protein ligase 1" O94822 21 28928144-28992956 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 326.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029143, CAB034164, HPA055604" Uncertain Enhanced Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 26 Cytosol "CAB034164: , HPA029143: , HPA055604: " "unprognostic (9.83e-2)" "unprognostic (5.11e-2)" "unprognostic (1.82e-2)" "unprognostic (2.22e-1)" "unprognostic (5.84e-2)" "unprognostic (9.35e-3)" "unprognostic (1.09e-2)" "unprognostic (1.11e-1)" "unprognostic (3.00e-2)" "potential prognostic favorable (5.45e-4)" "unprognostic (3.60e-2)" "unprognostic (1.51e-1)" "unprognostic (4.88e-2)" "unprognostic (1.44e-1)" "unprognostic (1.37e-1)" "unprognostic (1.11e-1)" "unprognostic (8.67e-2)" "potential prognostic favorable (9.42e-4)" "unprognostic (4.79e-3)" "unprognostic (3.20e-3)" "unprognostic (1.86e-2)" "unprognostic (1.69e-1)" "unprognostic (2.71e-1)" "unprognostic (1.88e-2)" "unprognostic (2.03e-1)" "unprognostic (1.57e-1)" "unprognostic (1.48e-1)" "unprognostic (2.05e-1)" "unprognostic (2.11e-2)" "unprognostic (9.07e-2)" LTO1 "CIAB1, ORAOV1, TAOS1" ENSG00000149716 "LTO1 maturation factor of ABCE1" Q8WV07 11 69653076-69675416 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062696 Approved Nucleoplasm NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 64: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 51: Secretory epithelial cells - Mixed function" 7 Nucleoplasm "HPA062696: " "unprognostic (2.82e-1)" "unprognostic (4.69e-2)" "unprognostic (7.53e-2)" "unprognostic (1.03e-1)" "unprognostic (2.16e-2)" "unprognostic (1.16e-1)" "unprognostic (2.11e-2)" "unprognostic (7.99e-3)" "unprognostic (3.37e-2)" "potential prognostic unfavorable (1.82e-4)" "unprognostic (1.27e-2)" "unprognostic (8.12e-3)" "unprognostic (1.33e-3)" "unprognostic (5.48e-2)" "unprognostic (1.58e-2)" "unprognostic (3.56e-1)" "unprognostic (2.28e-1)" "unprognostic (2.33e-1)" "unprognostic (2.74e-1)" "unprognostic (4.47e-2)" "unprognostic (1.72e-3)" "unprognostic (7.14e-2)" "unprognostic (2.76e-1)" "unprognostic (2.65e-1)" "unprognostic (6.16e-2)" "unprognostic (1.03e-1)" "unprognostic (1.31e-1)" "unprognostic (1.89e-1)" "unprognostic (3.86e-1)" LTV1 "C6orf93, dJ468K18.4, FLJ14909" ENSG00000135521 "LTV1 ribosome biogenesis factor" Q96GA3 6 143843338-143863812 "Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 42.6;Oocytes: 50.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030159, HPA030160, HPA030161" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 28: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 79 Cytosol Nucleoplasm "HPA030159: , HPA030160: , HPA030161: " "unprognostic (1.52e-2)" "potential prognostic unfavorable (4.50e-4)" "unprognostic (3.75e-2)" "unprognostic (3.61e-3)" "unprognostic (2.23e-1)" "unprognostic (6.35e-2)" "unprognostic (9.42e-2)" "unprognostic (5.78e-2)" "unprognostic (2.90e-2)" "potential prognostic unfavorable (1.91e-4)" "unprognostic (1.86e-1)" "unprognostic (4.22e-1)" "potential prognostic unfavorable (6.71e-6)" "potential prognostic unfavorable (1.08e-5)" "unprognostic (1.43e-3)" "unprognostic (3.72e-2)" "unprognostic (3.07e-2)" "unprognostic (1.37e-1)" "unprognostic (3.37e-3)" "unprognostic (6.51e-3)" "unprognostic (1.36e-1)" "unprognostic (3.07e-1)" "potential prognostic unfavorable (8.75e-4)" "unprognostic (9.29e-2)" "unprognostic (4.64e-3)" "unprognostic (3.56e-1)" "unprognostic (3.81e-1)" "unprognostic (2.34e-1)" "unprognostic (1.16e-1)" "unprognostic (7.83e-2)" "unprognostic (2.75e-1)" LUC7L "hLuc7B1, Luc7, LUC7B1" ENSG00000007392 "LUC7 like" Q9NQ29 16 188969-229463 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056424, HPA069321" Supported Approved Nucleoplasm,Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 64: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 35: RS4;11 - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 34 Nucleoplasm Mitochondria "HPA056424: , HPA069321: " "unprognostic (4.88e-2)" "unprognostic (2.10e-1)" "unprognostic (2.94e-1)" "unprognostic (1.78e-1)" "unprognostic (8.09e-2)" "unprognostic (1.50e-3)" "unprognostic (6.06e-2)" "unprognostic (2.14e-3)" "unprognostic (2.50e-1)" "unprognostic (4.87e-2)" "potential prognostic unfavorable (1.06e-7)" "unprognostic (3.16e-1)" "unprognostic (2.83e-2)" "unprognostic (1.80e-3)" "unprognostic (2.54e-2)" "unprognostic (1.46e-1)" "unprognostic (2.63e-1)" "unprognostic (1.90e-2)" "unprognostic (3.98e-2)" "unprognostic (1.34e-1)" "unprognostic (6.96e-3)" "potential prognostic favorable (2.53e-4)" "unprognostic (2.02e-3)" "unprognostic (2.91e-2)" "unprognostic (2.34e-2)" "unprognostic (2.65e-2)" "unprognostic (3.34e-3)" "unprognostic (5.11e-3)" "unprognostic (3.73e-1)" "unprognostic (9.13e-2)" "unprognostic (4.70e-2)" LUC7L2 "CGI-59, CGI-74, FLJ10657, H_NH0792N18.3, hLuc7B2, LUC7B2" ENSG00000146963 "LUC7 like 2, pre-mRNA splicing factor" Q9Y383 7 139340359-139423457 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 216.6;Bergmann glia: 247.7;Brain excitatory neurons: 243.5;Brain inhibitory neurons: 234.7;Choroid plexus epithelial cells: 228.2;Oligodendrocyte progenitor cells: 216.6;Oligodendrocytes: 315.1;Other brain neurons: 224.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051631 Approved Approved Nucleoplasm NA NA 200000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 64: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 39: Non-specific - Transcription" "Cluster 22: Non-specific - Basic cellular functions" 86 Nucleoplasm "HPA051631: " "potential prognostic favorable (5.64e-4)" "unprognostic (3.47e-1)" "unprognostic (2.41e-1)" "unprognostic (6.75e-3)" "unprognostic (3.36e-2)" "unprognostic (2.55e-1)" "unprognostic (2.31e-1)" "unprognostic (4.21e-2)" "unprognostic (1.42e-1)" "unprognostic (1.24e-2)" "unprognostic (1.85e-1)" "unprognostic (9.71e-3)" "unprognostic (2.57e-1)" "potential prognostic unfavorable (1.50e-5)" "unprognostic (1.55e-1)" "unprognostic (1.29e-2)" "unprognostic (2.56e-2)" "unprognostic (5.28e-2)" "unprognostic (1.21e-1)" "unprognostic (5.28e-3)" "unprognostic (3.63e-1)" "unprognostic (1.03e-2)" "unprognostic (2.28e-2)" "unprognostic (5.89e-2)" "unprognostic (1.03e-1)" "unprognostic (3.02e-1)" "unprognostic (1.78e-2)" "unprognostic (1.97e-2)" "unprognostic (1.83e-1)" "unprognostic (3.58e-2)" "unprognostic (4.26e-1)" LUC7L3 "CRA, CREAP-1, CROP, FLJ11063, hLuc7A, LUC7A, OA48-18" ENSG00000108848 "LUC7 like 3 pre-mRNA splicing factor" O95232 17 50719565-50756219 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018475, HPA018484, HPA020017" Enhanced Enhanced "Nuclear speckles" NA NA 7700 "Cluster 22: Eosinophils - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 94: Gonadal somatic cells - Mixed function" 18 "Nuclear speckles" "HPA018475: , HPA018484: , HPA020017: " "unprognostic (8.71e-2)" "unprognostic (9.98e-2)" "unprognostic (2.79e-1)" "unprognostic (4.20e-2)" "unprognostic (3.31e-3)" "unprognostic (2.17e-1)" "unprognostic (1.20e-2)" "unprognostic (2.28e-2)" "unprognostic (2.07e-1)" "unprognostic (2.01e-3)" "unprognostic (4.86e-3)" "unprognostic (1.52e-1)" "unprognostic (1.46e-1)" "potential prognostic unfavorable (1.51e-5)" "unprognostic (6.52e-2)" "unprognostic (9.69e-2)" "unprognostic (2.62e-1)" "unprognostic (4.68e-2)" "unprognostic (1.69e-3)" "unprognostic (1.46e-1)" "unprognostic (1.32e-1)" "unprognostic (2.02e-2)" "unprognostic (2.91e-3)" "unprognostic (3.56e-3)" "unprognostic (1.03e-1)" "unprognostic (6.36e-3)" "unprognostic (2.61e-2)" "unprognostic (2.03e-2)" "unprognostic (1.69e-1)" "unprognostic (7.31e-2)" "unprognostic (3.83e-2)" LUM "LDC, SLRR2D" ENSG00000139329 Lumican P51884 12 91102629-91111494 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 691.8;placenta: 503.6" "Cell type enriched" "Detected in many" 5 "Decidual stromal cells: 7752.5" "Group enriched" "Detected in some" 29 "fibroblast: 102.4;pericyte: 27.4" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in some" 4 "choroid plexus: 8.1" "Immune cell enriched" "Detected in single" 122 "basophil: 12.1" "Lineage enriched" "Detected in single" 122 "granulocytes: 12.1" "Cancer enhanced" "Detected in many" "Rhabdoid: 228.0" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Fibroblasts, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Minor Salivary Gland - Fibroblasts, Pituitary gland - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblasts_1, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 9 "spinal cord: 197.5" "HPA001522, CAB025783" Supported "Secreted to extracellular matrix" "No annotated function" NA NA 11000000000 "Cluster 46: Basophils - Proteolysis" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 12: Non-specific - Vasculature" "Cluster 5: Rhabdoid - Unknown function" "Cluster 108: Fibroblasts - ECM organization" 5 "CAB025783: , HPA001522: " "unprognostic (8.41e-3)" "unprognostic (1.48e-1)" "unprognostic (1.53e-1)" "unprognostic (3.62e-1)" "unprognostic (6.55e-2)" "unprognostic (1.31e-1)" "unprognostic (2.23e-2)" "unprognostic (4.77e-2)" "unprognostic (1.22e-1)" "unprognostic (3.14e-1)" "unprognostic (3.54e-2)" "unprognostic (4.86e-1)" "unprognostic (1.06e-3)" "unprognostic (2.35e-1)" "unprognostic (3.46e-2)" "unprognostic (3.35e-2)" "unprognostic (4.43e-2)" "unprognostic (1.20e-1)" "unprognostic (3.30e-1)" "unprognostic (1.45e-2)" "potential prognostic unfavorable (4.88e-6)" "unprognostic (3.16e-2)" "unprognostic (6.92e-2)" "unprognostic (5.12e-2)" "unprognostic (4.61e-2)" "unprognostic (2.08e-3)" "unprognostic (4.45e-2)" "unprognostic (6.12e-3)" "unprognostic (9.66e-3)" "unprognostic (2.87e-2)" "unprognostic (1.25e-2)" LURAP1 "C1orf190, FLJ25163, LRAP35a" ENSG00000171357 "Leucine rich adaptor protein 1" Q96LR2 1 46203334-46221256 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 132.4;Endometrial luminal cells: 169.2;Late primary spermatocytes: 135.2;Late spermatids: 509.9;Renal connecting tubule cells: 59.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030060, HPA030061" Uncertain Supported Vesicles,Cytosol NA NA "Cluster 67: Testis - Mixed function" "Cluster 30: White matter - Myelination" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 28 Cytosol Vesicles "HPA030060: , HPA030061: " "unprognostic (1.47e-2)" "unprognostic (9.62e-2)" "potential prognostic favorable (9.54e-5)" "unprognostic (4.80e-2)" "unprognostic (1.04e-1)" "unprognostic (3.06e-1)" "unprognostic (1.45e-1)" "unprognostic (7.89e-2)" "potential prognostic favorable (2.96e-4)" "unprognostic (3.24e-3)" "unprognostic (2.57e-2)" "unprognostic (3.02e-3)" "unprognostic (1.47e-1)" "unprognostic (6.81e-2)" "unprognostic (1.81e-2)" "unprognostic (1.14e-1)" "unprognostic (3.40e-1)" "unprognostic (1.40e-1)" "unprognostic (6.93e-2)" "unprognostic (1.37e-2)" "unprognostic (1.64e-1)" "unprognostic (2.33e-3)" "unprognostic (1.63e-1)" "unprognostic (2.17e-2)" "unprognostic (3.75e-3)" LURAP1L "bA3L8.2, C9orf150, FLJ38505, LRAP35b, MGC46502" ENSG00000153714 "Leucine rich adaptor protein 1 like" Q8IV03 9 12775020-12823060 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 200.0;Breast hormone-responsive cells: 302.7;Epididymal efferent duct absorptive cells: 337.2;Pancreatic duct cells: 276.7;Salivary acinar cells: 173.4" "Cell type enhanced" "Detected in all" "upper rhombic lip: 116.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Somatotropes, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA024407 Uncertain Approved Nucleoplasm,Nucleoli NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 25: Non-specific - Transcription" "Cluster 13: Non-specific - Mixed function" "Cluster 65: Non-specific - Cell growth & division" 10 Nucleoli Nucleoplasm "HPA024407: " "unprognostic (7.31e-2)" "unprognostic (2.20e-1)" "unprognostic (2.26e-1)" "unprognostic (2.79e-1)" "unprognostic (4.84e-2)" "unprognostic (7.93e-3)" "unprognostic (3.16e-2)" "unprognostic (2.66e-3)" "unprognostic (2.27e-1)" "validated prognostic favorable (5.41e-6)" "validated prognostic favorable (1.11e-5)" "unprognostic (3.08e-3)" "unprognostic (7.63e-2)" "unprognostic (8.89e-2)" "unprognostic (6.51e-2)" "unprognostic (2.83e-2)" "unprognostic (1.22e-1)" "unprognostic (1.10e-1)" "unprognostic (4.44e-2)" "unprognostic (2.94e-3)" "unprognostic (7.52e-2)" "unprognostic (1.60e-1)" "unprognostic (9.59e-2)" "potential prognostic favorable (4.49e-4)" "unprognostic (1.90e-1)" "unprognostic (4.73e-1)" "unprognostic (9.20e-2)" "unprognostic (3.56e-1)" "unprognostic (2.02e-2)" LUZP1 LUZP ENSG00000169641 "Leucine zipper protein 1" Q86V48 1 23084030-23177808 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 366.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 39.6" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Lung - Endothelial cells, Spleen - Endothelial cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028506, HPA028542, HPA028552" Enhanced Approved "Vesicles,Plasma membrane,Actin filaments,Cytokinetic bridge,Centrosome,Cytosol" Yes NA "Cluster 41: Basophils - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 24 "Actin filaments" "Vesicles, Plasma membrane, Cytokinetic bridge, Centrosome, Cytosol" "HPA028506: , HPA028542: , HPA028552: " "unprognostic (1.41e-1)" "unprognostic (1.09e-1)" "unprognostic (2.12e-1)" "unprognostic (3.36e-3)" "unprognostic (1.64e-2)" "unprognostic (7.75e-2)" "unprognostic (8.16e-2)" "unprognostic (1.55e-1)" "unprognostic (2.68e-1)" "unprognostic (1.86e-3)" "validated prognostic favorable (3.92e-7)" "validated prognostic favorable (5.65e-5)" "potential prognostic favorable (2.56e-4)" "unprognostic (5.01e-3)" "unprognostic (1.43e-1)" "unprognostic (2.70e-2)" "unprognostic (1.32e-3)" "unprognostic (9.91e-3)" "unprognostic (2.38e-1)" "unprognostic (9.69e-3)" "unprognostic (1.03e-3)" "unprognostic (5.40e-2)" "unprognostic (1.48e-1)" "unprognostic (2.64e-1)" "unprognostic (3.42e-2)" "unprognostic (5.53e-3)" "unprognostic (5.46e-2)" "unprognostic (2.78e-1)" "unprognostic (5.06e-1)" "unprognostic (1.98e-1)" "unprognostic (2.10e-1)" LUZP2 ENSG00000187398 "Leucine zipper protein 2" Q86TE4 11 24496970-25082638 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "adrenal gland: 6.1;brain: 16.6" "Cell type enriched" "Detected in many" 4 "Oligodendrocyte progenitor cells: 2829.7" "Cell type enhanced" "Detected in all" "eccentric medium spiny neuron: 2215.3;oligodendrocyte precursor cell: 3348.4" "Group enriched" "Detected in some" 10 "Glioblastoma Multiforme (TCGA): 9.6;Prostate Adenocarcinoma (TCGA): 10.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 5.7" "Adrenal gland - Adrenal cortex cells, Colon - Colon enteroendocrine cells, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039007, HPA046161" Enhanced Supported Approved "Nucleoplasm,Plasma membrane,Cytosol" "Secreted in brain" "No annotated function" NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 60: Prostate cancer - Unknown function" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA039007: , HPA046161: " "unprognostic (1.76e-1)" "unprognostic (7.49e-2)" "unprognostic (9.58e-3)" "unprognostic (3.10e-3)" "unprognostic (8.85e-3)" "unprognostic (1.52e-1)" "unprognostic (1.40e-1)" LUZP4 "CT-8, CT28, HOM-TES-85" ENSG00000102021 "Leucine zipper protein 4" Q9P127 X 115289715-115307563 "Predicted intracellular proteins" "mRNA transport, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 77 "testis: 7.6" "Group enriched" "Detected in some" 27 "Differentiating spermatogonia: 33.0;Early primary spermatocytes: 15.4;Undifferentiated spermatogonia: 45.5" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 8 "Testicular Germ Cell Tumor (TCGA): 22.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Myeloma: 1.1" "Testis - Spermatogonia" "HPA046436, HPA051999" Enhanced NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 24 "HPA046436: , HPA051999: " "unprognostic (9.04e-2)" "unprognostic (1.71e-1)" LVRN "APQ, AQPEP, FLJ90650, TAQPEP" ENSG00000172901 Laeverin Q6Q4G3 5 115962454-116027619 "Enzymes, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "adipose tissue: 10.3;placenta: 20.4" "Cell type enhanced" "Detected in some" "Adipocytes: 351.7;Corticotrophs: 60.4;Early spermatids: 47.7;Extravillous trophoblasts: 102.1;Fibro-adipogenic progenitors: 79.3;Late spermatids: 123.3" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 1.0;Gallbladder cancer: 1.9;thyroid cancer: 1.0" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Minor Salivary Gland - Adipocytes (Minor salivary gland), Stomach - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Smooth muscle cells" "Not detected" "Not detected" "Region enriched" "Detected in single" 8 "spinal cord: 3.3" HPA053254 Enhanced NA NA 3800 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 89: Adipocytes - Lipid metabolism" "HPA053254: " "unprognostic (4.91e-2)" "potential prognostic unfavorable (5.62e-7)" LXN ENSG00000079257 Latexin Q9BS40 3 158645822-158672648 "Predicted intracellular proteins" "Inflammatory response" "Heparin-binding, Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 135.9;Erythrocyte progenitors: 120.1;Fallopian tube ciliated cells: 196.4;Mast cells: 130.4;Mesothelial cells: 202.6;Platelets: 131.4;Prostatic club cells: 249.5;Respiratory ciliated cells: 136.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Liver - Vascular endothelial cells, Lung - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014179, CAB025128" Enhanced Approved Nucleoplasm,Cytosol No NA 880000 "Cluster 35: Neutrophils - Protein binding" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 48: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 21 "Nucleoplasm, Cytosol" "CAB025128: , HPA014179: " "unprognostic (3.74e-3)" "unprognostic (1.26e-1)" "unprognostic (6.87e-2)" "unprognostic (6.08e-2)" "unprognostic (9.34e-2)" "unprognostic (9.36e-2)" "unprognostic (6.92e-2)" "unprognostic (2.86e-2)" "unprognostic (5.91e-2)" "unprognostic (6.54e-2)" "validated prognostic favorable (9.11e-4)" "validated prognostic favorable (3.37e-5)" "unprognostic (1.03e-2)" "unprognostic (6.72e-2)" "unprognostic (2.06e-1)" "unprognostic (5.02e-2)" "unprognostic (2.96e-2)" "unprognostic (2.19e-2)" "unprognostic (2.22e-1)" "unprognostic (5.98e-2)" "unprognostic (2.03e-2)" "unprognostic (9.32e-2)" "unprognostic (6.32e-2)" "unprognostic (4.94e-2)" "unprognostic (4.15e-2)" "unprognostic (2.64e-2)" "unprognostic (5.66e-3)" "unprognostic (3.91e-2)" "unprognostic (6.92e-2)" "unprognostic (1.74e-1)" "unprognostic (1.58e-1)" LY6D E48 ENSG00000167656 "Lymphocyte antigen 6 family member D" Q14210 8 142784882-142786539 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 497.8;esophagus: 2201.7;skin 1: 899.4;vagina: 508.8" "Group enriched" "Detected in some" 5 "Esophageal apical cells: 7829.8;Esophageal basal cells: 7329.2;Esophageal suprabasal cells: 15063.4;Suprabasal keratinocytes: 4781.8" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Bladder Urothelial Carcinoma (TCGA): 854.6;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 1526.5;Head and Neck Squamous Cell Carcinoma (TCGA): 1567.6" "Region enhanced" "Detected in single" "cerebral cortex: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 204.9;Esophageal cancer: 170.2;head and neck cancer: 319.3" "Prostate - Urothelial cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA024755, HPA064317, CAB080499" Enhanced NA NA 72000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 3 "CAB080499: , HPA024755: , HPA064317: " "unprognostic (1.37e-2)" "unprognostic (1.62e-2)" "unprognostic (4.75e-2)" "unprognostic (5.43e-2)" "unprognostic (6.15e-3)" "unprognostic (1.41e-2)" "unprognostic (9.62e-2)" "unprognostic (3.42e-1)" "unprognostic (9.18e-2)" "unprognostic (5.19e-2)" "unprognostic (1.72e-2)" "unprognostic (9.70e-3)" "unprognostic (2.18e-2)" "unprognostic (1.73e-1)" "potential prognostic unfavorable (1.91e-6)" "unprognostic (3.55e-3)" "unprognostic (1.01e-1)" "unprognostic (1.32e-1)" "unprognostic (2.10e-1)" "unprognostic (2.99e-1)" "unprognostic (5.40e-2)" "unprognostic (2.03e-1)" "unprognostic (2.59e-2)" "unprognostic (1.08e-1)" LY6E "RIG-E, SCA-2, TSA-1" ENSG00000160932 "Lymphocyte antigen 6 family member E" Q16553 8 143017982-143023832 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 616.3" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 45.8;Brain inhibitory neurons: 26.2;Ependymal cells: 15.6;Extravillous trophoblasts: 23.3;Other brain neurons: 35.5;Papillary tip epithelial cells: 21.2;Podocytes: 18.3" "Cell type enhanced" "Detected in all" "endothelial cell: 291.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 756.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Skeletal muscle - Endothelial cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" Other NA NA 400000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 29: Forebrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 104: Brain endothelial cells - Blood brain barrier" 8 "unprognostic (3.41e-2)" "unprognostic (1.81e-1)" "unprognostic (5.44e-1)" "unprognostic (3.04e-1)" "unprognostic (2.58e-2)" "unprognostic (1.51e-1)" "unprognostic (2.33e-2)" "unprognostic (3.78e-1)" "unprognostic (2.97e-1)" "unprognostic (4.87e-2)" "unprognostic (9.18e-3)" "unprognostic (2.37e-2)" "unprognostic (1.54e-2)" "unprognostic (1.13e-1)" "unprognostic (1.32e-2)" "unprognostic (6.77e-2)" "unprognostic (1.03e-1)" "unprognostic (1.07e-1)" "unprognostic (2.70e-2)" "unprognostic (1.14e-1)" "unprognostic (3.12e-1)" "potential prognostic unfavorable (5.59e-4)" "unprognostic (1.65e-3)" "unprognostic (2.76e-2)" "unprognostic (3.65e-3)" "unprognostic (1.31e-2)" "unprognostic (2.13e-1)" "unprognostic (2.74e-1)" "unprognostic (5.19e-2)" "unprognostic (6.12e-3)" "unprognostic (4.44e-1)" LY6G5B "C6orf19, G5b" ENSG00000240053 "Lymphocyte antigen 6 family member G5B" Q8NDX9 6 31669976-31673776 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 8 "Astrocytes: 8.8;Bergmann glia: 8.0;Brain excitatory neurons: 6.5;Brain inhibitory neurons: 6.1;Choroid plexus epithelial cells: 10.0;Ependymal cells: 4.2;Microglia: 6.1;Oligodendrocyte progenitor cells: 4.8;Oligodendrocytes: 6.4;Other brain neurons: 4.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA048307 Approved "Secreted to blood" "No annotated function" NA NA "Cluster 64: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 56: Non-specific - Sensory perception" "Cluster 22: Non-specific - Basic cellular functions" "HPA048307: " "unprognostic (5.21e-2)" "unprognostic (5.29e-2)" "unprognostic (1.41e-1)" "unprognostic (8.41e-3)" "unprognostic (1.64e-2)" "unprognostic (5.94e-2)" "unprognostic (9.02e-2)" "unprognostic (2.30e-2)" "unprognostic (5.11e-3)" "unprognostic (4.63e-3)" "unprognostic (1.04e-2)" "unprognostic (2.00e-1)" "unprognostic (7.79e-3)" "unprognostic (8.26e-2)" "unprognostic (6.51e-2)" "unprognostic (7.70e-2)" "unprognostic (4.24e-2)" "unprognostic (2.08e-1)" "unprognostic (3.70e-2)" "unprognostic (1.45e-2)" "unprognostic (7.99e-3)" "potential prognostic favorable (3.36e-4)" "unprognostic (3.70e-2)" "unprognostic (8.35e-2)" "unprognostic (1.01e-1)" "unprognostic (1.01e-1)" "unprognostic (3.30e-2)" "unprognostic (6.91e-3)" LY6G5C "C6orf20, G5c, NG33" ENSG00000204428 "Lymphocyte antigen 6 family member G5C" Q5SRR4 6 31676684-31684040 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.4" "Cell type enhanced" "Detected in some" "Astrocytes: 2.0;Brain excitatory neurons: 2.4;Brain inhibitory neurons: 5.4;Differentiating spermatogonia: 2.0;Ependymal cells: 2.5;Gastric chief cells: 2.2;Late primary spermatocytes: 2.2;Oligodendrocyte progenitor cells: 2.6;Parietal cells: 5.3;Platelets: 8.5;Respiratory ionocytes: 2.5" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA038690 Approved "Secreted - unknown location" "No annotated function" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 27: Cerebellum - Synaptic function" "Cluster 15: Non-specific - Transcription" "Cluster 50: Lymphoma - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" "HPA038690: " "unprognostic (3.28e-1)" "unprognostic (5.36e-3)" "unprognostic (2.58e-1)" "unprognostic (1.90e-1)" "unprognostic (1.37e-1)" LY6G6C "C6orf24, G6c, NG24" ENSG00000204421 "Lymphocyte antigen 6 family member G6C" O95867 6 31718648-31721746 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "skin 1: 553.8" "Group enriched" "Detected in some" 6 "Early spermatids: 2.6;Esophageal apical cells: 3.7;Late spermatids: 8.0;Suprabasal keratinocytes: 2.9" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 31.2;Skin Cutaneous Melanoma (TCGA): 26.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 5.6" "Adipose visceral - Mesothelial cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 37: Skin - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 8 "unprognostic (1.79e-1)" "unprognostic (7.33e-2)" "unprognostic (5.95e-2)" "unprognostic (4.36e-2)" "unprognostic (1.10e-1)" "unprognostic (9.35e-3)" "unprognostic (2.67e-1)" "unprognostic (9.39e-2)" "unprognostic (6.20e-2)" "unprognostic (6.91e-2)" "unprognostic (5.97e-2)" "unprognostic (8.12e-3)" "unprognostic (2.35e-1)" "unprognostic (2.25e-1)" "unprognostic (3.16e-1)" "unprognostic (6.31e-2)" "unprognostic (7.17e-2)" LY6G6D "C6orf23, G6D, Ly6-D, MEGT1, NG25" ENSG00000244355 "Lymphocyte antigen 6 family member G6D" O95868 6 31715348-31717919 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "skin 1: 33.5" "Cell type enriched" "Detected in single" 5 "Platelets: 2.8" "Not detected" "Not detected" "Group enriched" "Detected in some" 29 "Colon Adenocarcinoma (TCGA): 16.4;Rectum Adenocarcinoma (TCGA): 25.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 16 "colorectal cancer: 46.5" "Pituitary gland - Undifferentiated cells (Pituitary gland), Skin - Hair cortex cells, Skin - Inner root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Region enhanced" "Detected in many" "cerebellum: 6.1" "Not detected" "Not detected" HPA054412 Uncertain "Intracellular and membrane" "No annotated function" NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 47: Platelets - Hemostasis" 7 "HPA054412: " "unprognostic (1.62e-1)" "unprognostic (5.43e-2)" "unprognostic (2.26e-2)" "unprognostic (1.06e-2)" LY6G6F "C6orf21, G6f, LY6G6D, NG32" ENSG00000204424 "Lymphocyte antigen 6 family member G6F" Q5SQ64 6 31706866-31710679 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 3.6;lymphoid tissue: 1.2;skin 1: 1.3" "Cell type enriched" "Detected in some" 6 "Platelets: 518.8" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 5 "neutrophil: 2.6" "Lineage enriched" "Detected in single" 5 "granulocytes: 2.6" "Cancer enhanced" "Detected in some" "colorectal cancer: 1.7;Leukemia: 1.4" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA008053 Uncertain NA NA 760000 "Cluster 4: Neutrophils - Degranulation" "Cluster 15: Bone marrow - Innate immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 47: Platelets - Hemostasis" 6 "HPA008053: " "unprognostic (2.05e-1)" "unprognostic (3.22e-2)" LY6G6F-LY6G6D "G6F-LY6G6D, MEGT-1, MEGT1" ENSG00000250641 "LY6G6F-LY6G6D readthrough" 6 31706904-31717918 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 22 "testis: 2.5" "Cell type enhanced" "Detected in single" "Platelets: 1.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Rectum Adenocarcinoma (TCGA): 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA008053 Uncertain NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 47: Leukemia - Hemostasis" "Cluster 47: Platelets - Hemostasis" "HPA008053: " "unprognostic (3.30e-1)" LY6H NMLY6 ENSG00000176956 "Lymphocyte antigen 6 family member H" O94772 8 143157914-143160711 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 421.1" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 81.5;Brain inhibitory neurons: 95.9;Ependymal cells: 26.6;Oligodendrocyte progenitor cells: 49.7;Oligodendrocytes: 13.4;Other brain neurons: 216.7" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Glioblastoma Multiforme (TCGA): 20.9;Pancreatic Adenocarcinoma (TCGA): 6.9;Testicular Germ Cell Tumor (TCGA): 8.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 1.6;lung cancer: 1.3" "Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077218 Enhanced "Intracellular and membrane" "No annotated function" NA NA 60000 "Cluster 78: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 98: Neurons - Neurotransmission & signaling" 21 "HPA077218: " "unprognostic (2.62e-1)" "unprognostic (4.01e-3)" "unprognostic (3.82e-2)" "unprognostic (3.18e-3)" "unprognostic (1.46e-1)" "unprognostic (3.92e-3)" "unprognostic (2.12e-2)" "unprognostic (9.66e-3)" "potential prognostic favorable (8.02e-4)" "unprognostic (2.64e-1)" LY6K "CT97, FLJ35226, HSJ001348" ENSG00000160886 "Lymphocyte antigen 6 family member K" Q17RY6 8 142700111-142705127 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 12.0;testis: 35.1" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 84.4;Differentiating spermatogonia: 81.7;Early primary spermatocytes: 419.0;Esophageal apical cells: 278.0;Esophageal suprabasal cells: 71.0;Extravillous trophoblasts: 277.7;Suprabasal keratinocytes: 54.8" "Cell type enhanced" "Detected in some" "endothelial cell: 3.6;pericyte: 1.5" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 67.8;Head and Neck Squamous Cell Carcinoma (TCGA): 49.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "neutrophil: 1.7" "Lineage enriched" "Detected in single" 15 "granulocytes: 1.7" "Cancer enriched" "Detected in many" 5 "Adrenocortical cancer: 742.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA017770, CAB075742, CAB075743, CAB079929, CAB080500" Enhanced Uncertain "Nucleoplasm,Plasma membrane,Actin filaments,Acrosome,Equatorial segment,Mid piece" "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 39: Testis - Nuclear processes" "Cluster 24: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 3: Early primary spermatocytes - Early meiosis" "Plasma membrane, Acrosome, Mid piece" "Nucleoplasm, Actin filaments, Equatorial segment" "CAB075742: , CAB075743: , CAB079929: , CAB080500: , HPA017770: " "unprognostic (1.11e-2)" "unprognostic (2.63e-1)" "unprognostic (2.02e-1)" "unprognostic (2.95e-2)" "unprognostic (1.90e-1)" "unprognostic (1.06e-1)" "unprognostic (4.00e-1)" "unprognostic (3.84e-2)" "potential prognostic unfavorable (6.34e-4)" "unprognostic (1.80e-1)" "unprognostic (3.38e-1)" "validated prognostic unfavorable (6.73e-4)" "validated prognostic unfavorable (3.06e-4)" "unprognostic (4.13e-2)" "unprognostic (2.81e-1)" "unprognostic (9.31e-2)" "unprognostic (5.94e-2)" "unprognostic (3.77e-2)" "unprognostic (4.93e-2)" "unprognostic (3.65e-1)" "unprognostic (1.40e-1)" "unprognostic (6.31e-2)" "unprognostic (4.53e-2)" "unprognostic (9.69e-2)" LY6L ENSG00000261667 "Lymphocyte antigen 6 family member L" H3BQJ8 8 143080630-143083486 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 11 "epididymis: 5.8;kidney: 2.2" "Cell type enriched" "Detected in some" 4 "Respiratory ionocytes: 10.2" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Kidney Chromophobe (TCGA): 1.8;Prostate Adenocarcinoma (TCGA): 2.1" "Region enhanced" "Detected in some" "thalamus: 5.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 27 "breast cancer: 2.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 38: Sub-cortical - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" "unprognostic (1.71e-1)" "unprognostic (2.80e-1)" LY6S ENSG00000291309 "Lymphocyte antigen 6 family member S" 8 143041844-143045678 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in single" "Late spermatids: 2.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" NA NA "Cluster 66: Lymphoid tissue - Immune response" "Cluster 38: Sub-cortical - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" LY75 "CD205, CLEC13B, DEC-205" ENSG00000054219 "Lymphocyte antigen 75" O60449 2 159803355-159904756 "CD markers, Predicted membrane proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 73.1" "Cell type enriched" "Detected in some" 17 "Microglia: 69.9" "Group enriched" "Detected in many" 11 "central nervous system macrophage: 81.4;endothelial cell: 42.3;leukocyte: 73.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "lymphoma: 19.6;Myeloma: 18.0" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB001450, HPA049108, HPA054073" Enhanced Approved "Golgi apparatus" NA NA 670000 "Cluster 24: Non-specific - Transcription" "Cluster 80: Thymus - Adaptive immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 1 "Golgi apparatus" "CAB001450: , HPA049108: , HPA054073: " "unprognostic (5.74e-2)" "unprognostic (1.10e-2)" "unprognostic (2.42e-1)" "unprognostic (1.07e-1)" "unprognostic (1.57e-1)" "unprognostic (1.00e-1)" "unprognostic (2.83e-2)" "unprognostic (3.75e-2)" "unprognostic (1.35e-2)" "unprognostic (2.09e-1)" "unprognostic (1.16e-2)" "unprognostic (1.27e-1)" "unprognostic (1.25e-1)" "unprognostic (2.42e-1)" "unprognostic (1.47e-3)" "unprognostic (1.10e-1)" "unprognostic (3.57e-2)" "unprognostic (1.61e-1)" "unprognostic (6.26e-2)" "unprognostic (8.26e-2)" "potential prognostic unfavorable (3.37e-4)" "unprognostic (1.41e-1)" "unprognostic (2.35e-1)" "unprognostic (5.82e-3)" "unprognostic (6.95e-2)" "unprognostic (1.80e-1)" "unprognostic (3.00e-1)" "unprognostic (3.40e-1)" "unprognostic (5.90e-2)" LY75-CD302 ENSG00000248672 "LY75-CD302 readthrough" 2 159771851-159904710 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 2.2;intestine: 1.7;lymphoid tissue: 2.2" "Cell type enhanced" "Detected in some" "Epicardial cells: 9.1;Medullary thymic epithelial cells: 4.8;Neutrophil progenitors: 4.3;Neutrophils: 6.4;Thymocytes: 7.6" "Cancer enhanced" "Detected in single" "Stomach Adenocarcinoma (TCGA): 1.2" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Myeloma: 4.2" HPA049108 Uncertain NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 77: Intestine - Digestion" "Cluster 43: Hindbrain - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" "HPA049108: " "unprognostic (1.32e-1)" "unprognostic (4.58e-1)" "unprognostic (1.12e-1)" "unprognostic (7.46e-2)" "unprognostic (3.76e-2)" "unprognostic (3.27e-1)" LY86 "dJ80N2.1, MD-1" ENSG00000112799 "Lymphocyte antigen 86" O95711 6 6588108-6654983 "Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 73.4" "Cell type enhanced" "Detected in many" "B-cells: 225.2;cDC: 163.0;Hofbauer cells: 230.3;Kupffer cells: 223.4;Macrophages: 145.7;Microglia: 604.7;Monocyte progenitors: 115.5;monocytes: 145.9" "Cell type enriched" "Detected in many" 26 "central nervous system macrophage: 762.5" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 57.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 427.5;myeloid DC: 427.0" "Group enriched" "Detected in all" 43 "B-cells: 336.4;dendritic cells: 427.0;monocytes: 427.5" "Group enriched" "Detected in some" 4 "Leukemia: 42.0;lymphoma: 44.4" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Colon - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Langerhans cells, Testis - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB025000, HPA044895" Approved "Secreted to blood" Immunity NA NA 39000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 119 "CAB025000: , HPA044895: " "unprognostic (1.78e-1)" "unprognostic (2.82e-2)" "unprognostic (6.58e-2)" "unprognostic (1.30e-3)" "unprognostic (2.02e-2)" "unprognostic (6.14e-2)" "unprognostic (1.10e-1)" "unprognostic (5.54e-2)" "unprognostic (4.19e-1)" "unprognostic (1.45e-1)" "unprognostic (3.23e-2)" "unprognostic (2.26e-1)" "unprognostic (3.76e-3)" "unprognostic (2.72e-1)" "unprognostic (1.74e-2)" "potential prognostic favorable (2.02e-4)" "unprognostic (5.36e-2)" "unprognostic (2.50e-1)" "unprognostic (1.92e-1)" "unprognostic (1.59e-1)" "unprognostic (4.12e-2)" "unprognostic (1.31e-1)" "unprognostic (8.00e-2)" "unprognostic (1.01e-1)" "unprognostic (1.69e-1)" "unprognostic (3.84e-2)" "unprognostic (3.98e-2)" "unprognostic (4.79e-2)" "unprognostic (1.12e-3)" "unprognostic (9.55e-2)" "unprognostic (1.87e-1)" LY9 "CD229, hly9, mLY9, SLAMF3" ENSG00000122224 "Lymphocyte antigen 9" Q9HBG7 1 160796074-160828261 "CD markers, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Cell adhesion, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.9;intestine: 11.2;lymphoid tissue: 29.2" "Cell type enhanced" "Detected in some" "B-cells: 425.1;cDC: 47.6;Innate lymphoid cells: 28.3;NK-cells: 53.0;pDCs: 102.5;Plasma cells: 124.2;T-cells: 73.5" "Cell type enriched" "Detected in single" 149 "leukocyte: 105.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "gdT-cell: 113.2;MAIT T-cell: 113.7;memory B-cell: 56.2;memory CD4 T-cell: 97.8;memory CD8 T-cell: 109.8;naive B-cell: 53.0;naive CD4 T-cell: 110.0;naive CD8 T-cell: 112.6;plasmacytoid DC: 73.0;T-reg: 80.5" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "lymphoma: 15.9;Myeloma: 38.0" "Adipose visceral - T-cells, Adrenal gland - T-cells, Colon - T-cells, Heart muscle - T-cells, Liver - T-cells, Minor Salivary Gland - Plasma cells, Pancreas - T-cells, Prostate - T-cells, Skin - T-cells, Spleen - B-cells (Spleen), Thyroid gland - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA050917 Approved Approved "Plasma membrane,Centriolar satellite" "Secreted - unknown location" Immunity NA NA 25000 "Cluster 11: T-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 1 "Plasma membrane" "Centriolar satellite" "HPA050917: " "unprognostic (8.79e-2)" "unprognostic (2.67e-3)" "unprognostic (1.12e-1)" "potential prognostic favorable (4.94e-4)" "unprognostic (5.62e-2)" "unprognostic (2.44e-1)" "potential prognostic favorable (1.37e-4)" "unprognostic (1.07e-1)" "unprognostic (8.10e-2)" "unprognostic (2.28e-1)" "unprognostic (3.03e-3)" "potential prognostic favorable (1.86e-4)" "unprognostic (1.42e-2)" "unprognostic (1.66e-1)" "unprognostic (5.74e-2)" "unprognostic (2.82e-1)" "unprognostic (5.85e-2)" "unprognostic (2.86e-1)" "unprognostic (1.11e-3)" "potential prognostic favorable (3.48e-4)" "unprognostic (4.69e-2)" "unprognostic (5.81e-2)" "unprognostic (2.47e-2)" LY96 MD-2 ENSG00000154589 "Lymphocyte antigen 96" Q9Y6Y9 8 73991392-74029079 "Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 61.4" "Group enriched" "Detected in many" 4 "Hofbauer cells: 1025.7;Kupffer cells: 1097.7;Neutrophils: 598.2" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 77.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 632.0" "Lineage enriched" "Detected in many" 7 "granulocytes: 632.0" "Low cancer specificity" "Detected in many" "Colon - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053060 Approved Vesicles "Secreted to blood" Immunity NA NA 76000 "Cluster 28: Neutrophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 7: Liver cancer - Metabolism" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 5 Vesicles "HPA053060: " "unprognostic (1.50e-1)" "unprognostic (2.62e-1)" "unprognostic (4.45e-1)" "unprognostic (8.37e-3)" "unprognostic (5.84e-2)" "unprognostic (3.02e-1)" "unprognostic (9.85e-3)" "unprognostic (2.69e-2)" "unprognostic (1.45e-1)" "unprognostic (6.56e-3)" "potential prognostic unfavorable (6.94e-6)" "unprognostic (2.17e-2)" "unprognostic (1.18e-3)" "potential prognostic unfavorable (7.38e-4)" "unprognostic (2.48e-1)" "unprognostic (3.33e-1)" "unprognostic (4.10e-1)" "unprognostic (4.12e-2)" "unprognostic (2.86e-2)" "unprognostic (2.26e-1)" "unprognostic (8.84e-2)" "unprognostic (8.30e-2)" "unprognostic (1.96e-1)" "unprognostic (3.20e-1)" "unprognostic (5.29e-2)" "unprognostic (6.54e-2)" "unprognostic (5.00e-2)" "unprognostic (2.29e-2)" "unprognostic (5.05e-3)" "unprognostic (1.68e-2)" "unprognostic (1.60e-1)" LYAR "ZC2HC2, ZLYAR" ENSG00000145220 "Ly1 antibody reactive" Q9NX58 4 4267701-4290154 "Predicted intracellular proteins, Transcription factors" "Immunity, Innate immunity, rRNA processing, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "testis: 95.4" "Cell type enriched" "Detected in many" 8 "Late primary spermatocytes: 1609.5" "Cell type enhanced" "Detected in all" "leukocyte: 33.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pituitary gland - Corticotropes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035880, HPA035881" Enhanced Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 39: Testis - Nuclear processes" "Cluster 11: White matter - Signal transduction" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 172 "Nucleoli rim" "Nucleoplasm, Nucleoli" "HPA035880: , HPA035881: " "unprognostic (1.21e-2)" "unprognostic (2.34e-2)" "unprognostic (4.23e-1)" "unprognostic (3.30e-3)" "unprognostic (1.17e-1)" "unprognostic (2.50e-2)" "unprognostic (1.28e-1)" "unprognostic (1.14e-2)" "unprognostic (9.51e-3)" "unprognostic (1.63e-2)" "unprognostic (2.01e-1)" "unprognostic (9.85e-2)" "potential prognostic unfavorable (4.83e-7)" "validated prognostic unfavorable (8.67e-7)" "validated prognostic unfavorable (2.45e-6)" "validated prognostic unfavorable (1.97e-6)" "validated prognostic unfavorable (4.49e-4)" "unprognostic (1.14e-1)" "unprognostic (9.36e-2)" "unprognostic (4.66e-3)" "unprognostic (3.96e-2)" "unprognostic (3.19e-3)" "unprognostic (1.46e-2)" "unprognostic (4.26e-2)" "unprognostic (8.92e-3)" "unprognostic (6.57e-2)" "unprognostic (3.13e-1)" "unprognostic (2.14e-1)" "unprognostic (1.78e-1)" "unprognostic (1.59e-2)" "unprognostic (4.08e-3)" LYG1 "LYGA1, SALW1939" ENSG00000144214 "Lysozyme g1" Q8N1E2 2 99284238-99304742 "Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 22.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 27.0;Epicardial cells: 15.9;Myonuclei: 20.9;Proximal tubule cells: 14.1;Retinal ganglion cells: 15.5;Retinal horizontal cells: 16.0;Thymic myoid cells: 19.0" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" 24 "Kidney Renal Clear Cell Carcinoma (TCGA): 31.4;Kidney Renal Papillary Cell Carcinoma (TCGA): 109.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Secreted in other tissues" Enzyme NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 37: Neurons - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 3 "unprognostic (3.36e-2)" "unprognostic (2.85e-2)" "unprognostic (7.15e-2)" "unprognostic (5.64e-2)" "unprognostic (2.23e-1)" "potential prognostic unfavorable (6.23e-4)" "unprognostic (1.29e-1)" "potential prognostic favorable (5.66e-4)" "potential prognostic favorable (2.03e-5)" "unprognostic (1.99e-2)" "potential prognostic favorable (4.03e-4)" "unprognostic (2.07e-1)" "unprognostic (4.38e-1)" "unprognostic (6.16e-2)" "unprognostic (3.98e-2)" "unprognostic (3.29e-2)" "unprognostic (8.48e-3)" "unprognostic (1.48e-2)" "unprognostic (6.89e-2)" "unprognostic (2.05e-2)" "unprognostic (4.58e-2)" "unprognostic (1.70e-1)" "unprognostic (1.24e-1)" "unprognostic (1.41e-1)" "unprognostic (1.47e-1)" LYG2 "LYGA2, LYGH" ENSG00000185674 "Lysozyme g2" Q86SG7 2 99242246-99255666 "Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "retina: 3.2;skin 1: 7.9" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 14.7;Cardiomyocytes: 37.6;Epicardial cells: 15.9;Myonuclei: 16.5;Retinal bipolar cells: 13.8;Retinal ganglion cells: 34.8;Retinal horizontal cells: 24.0;Rod photoreceptor cells: 22.6" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Ovary Serous Cystadenocarcinoma (TCGA): 2.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in some" "Skin - Hair cortex cells, Skin - Inner root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA039179 Uncertain "Secreted in other tissues" Enzyme NA NA "Cluster 24: Non-specific - Transcription" "Cluster 37: Skin - Keratinization" "Cluster 2: Neurons - Nucleosome" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 12 "HPA039179: " "unprognostic (1.18e-1)" "unprognostic (3.36e-1)" "unprognostic (6.99e-2)" "unprognostic (2.74e-1)" "unprognostic (6.29e-3)" LYL1 bHLHa18 ENSG00000104903 "LYL1 basic helix-loop-helix family member" P12980 19 13099033-13103161 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 33.8;lymphoid tissue: 35.3" "Cell type enhanced" "Detected in many" "Early spermatids: 365.7;Erythrocytes: 160.6;Hematopoietic stem cells: 132.0;Hofbauer cells: 200.1;Late primary spermatocytes: 298.6;Late spermatids: 1265.1;Megakaryocyte-Erythroid progenitors: 134.3;Megakaryocytes: 500.7;Platelets: 697.1" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 55.0;endothelial cell: 28.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 6.4" "Group enriched" "Detected in many" 4 "B-cells: 3.7;granulocytes: 6.4;monocytes: 2.8" "Group enriched" "Detected in many" 12 "Leukemia: 125.2;lymphoma: 33.7" "Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA072177 Approved Nucleoplasm NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 47: Platelets - Hemostasis" 2 Nucleoplasm "HPA072177: " "unprognostic (2.38e-2)" "unprognostic (6.64e-2)" "unprognostic (3.46e-2)" "unprognostic (5.41e-2)" "unprognostic (1.98e-3)" "unprognostic (2.88e-1)" "unprognostic (4.67e-1)" "unprognostic (6.08e-2)" "unprognostic (1.04e-2)" "unprognostic (6.35e-2)" "unprognostic (8.47e-2)" "unprognostic (3.01e-1)" "unprognostic (5.55e-2)" "unprognostic (1.80e-1)" "unprognostic (2.36e-2)" "unprognostic (3.83e-3)" "unprognostic (2.10e-1)" "unprognostic (9.58e-2)" "unprognostic (8.80e-2)" "unprognostic (1.68e-1)" "potential prognostic favorable (3.91e-4)" "unprognostic (1.38e-1)" "unprognostic (4.63e-2)" "unprognostic (4.90e-2)" "unprognostic (2.70e-1)" "unprognostic (5.59e-2)" "unprognostic (6.84e-2)" "unprognostic (4.30e-2)" "unprognostic (2.71e-1)" "unprognostic (7.58e-2)" LYN JTK8 ENSG00000254087 "LYN proto-oncogene, Src family tyrosine kinase" P07948 8 55879835-56014169 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Adaptive immunity, Host-virus interaction, Immunity, Inflammatory response, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 69.6;lymphoid tissue: 80.3" "Cell type enriched" "Detected in many" 4 "Neutrophils: 6578.7" "Group enriched" "Detected in all" 6 "central nervous system macrophage: 650.5;leukocyte: 398.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 64.6" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Neutrophils_2, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001231, CAB004492" Enhanced Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA 350000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 112 "Plasma membrane" "Golgi apparatus, Vesicles" "CAB004492: , HPA001231: " "unprognostic (2.94e-1)" "unprognostic (2.93e-2)" "unprognostic (1.28e-1)" "unprognostic (1.78e-1)" "unprognostic (5.89e-2)" "unprognostic (1.59e-1)" "unprognostic (3.06e-1)" "unprognostic (5.10e-2)" "unprognostic (2.39e-1)" "unprognostic (2.74e-3)" "potential prognostic favorable (6.64e-4)" "unprognostic (1.79e-1)" "unprognostic (9.35e-3)" "unprognostic (9.32e-3)" "unprognostic (1.05e-1)" "unprognostic (3.29e-1)" "unprognostic (1.49e-2)" "unprognostic (1.73e-1)" "unprognostic (3.22e-1)" "unprognostic (8.22e-2)" "unprognostic (9.27e-2)" "unprognostic (1.69e-2)" "unprognostic (3.42e-1)" "unprognostic (3.00e-1)" "unprognostic (8.31e-2)" "unprognostic (4.61e-1)" "unprognostic (1.01e-1)" "unprognostic (3.31e-1)" "unprognostic (3.34e-3)" "unprognostic (2.78e-1)" "unprognostic (2.74e-1)" LYNX1 SLURP2 ENSG00000180155 "Ly6/neurotoxin 1" P0DP58 8 142771197-142777810 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 124.9;heart muscle: 74.4" "Cell type enhanced" "Detected in some" "Astrocytes: 10.5;Bergmann glia: 6.5;Brain excitatory neurons: 25.9;Brain inhibitory neurons: 18.9;Breast lactating cells: 5.6;Choroid plexus epithelial cells: 15.5;Ependymal cells: 6.0;Microglia: 6.5;Oligodendrocyte progenitor cells: 6.9;Oligodendrocytes: 14.3;Other brain neurons: 27.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "intermediate monocyte: 6.6;non-classical monocyte: 17.6" "Lineage enriched" "Detected in many" 18 "monocytes: 17.6" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 410000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 35: Non-specific - Mixed function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 109: Neurons - Neuronal signaling" "unprognostic (4.81e-2)" "unprognostic (5.75e-3)" "unprognostic (1.22e-2)" "unprognostic (1.04e-1)" "unprognostic (7.41e-3)" "unprognostic (1.16e-2)" "unprognostic (1.68e-2)" "unprognostic (5.19e-2)" "unprognostic (1.03e-1)" "unprognostic (2.95e-1)" "unprognostic (1.36e-2)" "potential prognostic favorable (7.33e-4)" "unprognostic (1.09e-1)" "unprognostic (1.54e-2)" "potential prognostic favorable (1.18e-5)" "unprognostic (1.43e-1)" "unprognostic (5.18e-2)" "unprognostic (3.37e-2)" "potential prognostic unfavorable (1.54e-4)" "unprognostic (3.33e-1)" "unprognostic (1.07e-2)" "unprognostic (1.37e-2)" "unprognostic (1.73e-2)" "unprognostic (4.73e-2)" "unprognostic (3.92e-2)" "unprognostic (2.88e-2)" "unprognostic (1.01e-2)" "unprognostic (8.86e-2)" "unprognostic (2.42e-2)" "unprognostic (1.77e-2)" LYNX1-SLURP2 ENSG00000284505 "LYNX1-SLURP2 readthrough" 8 142764334-142778224 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 6.4" "Cell type enriched" "Detected in some" 5 "Esophageal apical cells: 230.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.4" "Lineage enriched" "Detected in single" 8 "monocytes: 1.4" "Low cancer specificity" "Detected in single" "Intracellular and membrane" NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 84: Apical squamous epithelium - Cornification" "unprognostic (2.81e-3)" "unprognostic (4.28e-3)" "unprognostic (4.21e-3)" "unprognostic (1.03e-3)" "unprognostic (5.43e-2)" "unprognostic (2.60e-2)" LYPD1 "LYPDC1, MGC29643" ENSG00000150551 "LY6/PLAUR domain containing 1" Q8N2G4 2 132643286-132671579 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 35.8;fallopian tube: 50.3;pituitary gland: 14.0" "Cell type enhanced" "Detected in many" "Bergmann glia: 46.7;Ependymal cells: 52.3;Epididymal efferent duct ciliated cells: 47.4;Fallopian secretory cells: 249.4;Oligodendrocyte progenitor cells: 57.0;Oocytes: 175.0;Pituitary stem cells: 128.6;Salivary acinar cells: 42.9" "Cell type enhanced" "Detected in many" "ependymal cell: 119.1" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 72.1;Ovary Serous Cystadenocarcinoma (TCGA): 134.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "eosinophil: 3.6" "Lineage enriched" "Detected in single" 22 "granulocytes: 3.6" "Cancer enhanced" "Detected in many" "skin cancer: 51.7" "Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA068333 Approved "Nucleoplasm,Vesicles,Plasma membrane" "Intracellular and membrane" "No annotated function" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 46: Brainstem - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" "Nucleoplasm, Vesicles" "Plasma membrane" "HPA068333: " "unprognostic (7.71e-2)" "unprognostic (1.84e-1)" "unprognostic (2.51e-2)" "unprognostic (4.00e-3)" "unprognostic (9.22e-3)" "unprognostic (1.85e-1)" "unprognostic (6.60e-3)" "unprognostic (7.17e-3)" "unprognostic (2.58e-2)" "unprognostic (1.12e-2)" "unprognostic (4.81e-2)" "unprognostic (5.18e-2)" "unprognostic (1.39e-2)" "unprognostic (2.06e-2)" "unprognostic (1.13e-2)" "unprognostic (1.29e-3)" "unprognostic (3.90e-2)" "unprognostic (1.19e-1)" "unprognostic (1.72e-2)" "unprognostic (2.36e-3)" "unprognostic (4.99e-2)" "unprognostic (1.48e-2)" "unprognostic (9.84e-2)" "unprognostic (1.66e-2)" "unprognostic (2.72e-3)" "unprognostic (1.64e-2)" "unprognostic (1.11e-1)" "unprognostic (2.29e-2)" "unprognostic (1.39e-2)" LYPD2 "LYPDC2, RGTR430, UNQ430" ENSG00000197353 "LY6/PLAUR domain containing 2" Q6UXB3 8 142750150-142752532 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "esophagus: 338.7" "Cell type enriched" "Detected in some" 7 "Esophageal apical cells: 18672.2" "Cell type enriched" "Detected in single" 89 "leukocyte: 9.0" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 91.6;Ovary Serous Cystadenocarcinoma (TCGA): 76.7" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in some" 13 "non-classical monocyte: 442.4" "Lineage enriched" "Detected in many" 22 "monocytes: 442.4" "Cancer enhanced" "Detected in some" "Bladder cancer: 10.3;head and neck cancer: 6.1;pancreatic cancer: 6.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Intracellular and membrane" "No annotated function" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 37: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 84: Apical squamous epithelium - Cornification" 1 "unprognostic (7.93e-2)" "unprognostic (2.22e-3)" "unprognostic (1.10e-3)" "unprognostic (3.66e-2)" "unprognostic (3.66e-1)" "unprognostic (8.35e-2)" "unprognostic (1.27e-2)" "unprognostic (3.93e-3)" "unprognostic (6.79e-2)" "unprognostic (5.24e-3)" "potential prognostic unfavorable (1.76e-5)" "unprognostic (2.30e-1)" "unprognostic (3.24e-1)" "unprognostic (7.59e-2)" "unprognostic (8.19e-2)" LYPD3 C4.4A ENSG00000124466 "LY6/PLAUR domain containing 3" O95274 19 43460787-43465608 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 347.9;esophagus: 1070.5;skin 1: 661.0;vagina: 483.6" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 6603.7;Esophageal basal cells: 1138.2;Esophageal suprabasal cells: 4473.6;Ocular epithelial cells: 1242.4;Suprabasal keratinocytes: 2733.3;Syncytiotrophoblasts: 1118.9" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 2.6;endothelial cell: 2.1;pericyte: 2.0" "Group enriched" "Detected in many" 6 "Bladder Urothelial Carcinoma (TCGA): 301.7;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 386.3;Head and Neck Squamous Cell Carcinoma (TCGA): 515.0;Lung Squamous Cell Carcinoma (TCGA): 138.8;Skin Cutaneous Melanoma (TCGA): 141.7" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 5.5" "Group enriched" "Detected in many" 9 "dendritic cells: 2.6;granulocytes: 2.1;T-cells: 5.5" "Cancer enhanced" "Detected in many" "cervical cancer: 111.3" "Prostate - Urothelial cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041529, HPA041797, HPA077859" Enhanced Approved "Endoplasmic reticulum,Vesicles" NA NA 2500000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 19 "Endoplasmic reticulum, Vesicles" "HPA041529: , HPA041797: , HPA077859: " "unprognostic (4.85e-2)" "unprognostic (9.93e-2)" "unprognostic (1.63e-1)" "unprognostic (3.58e-1)" "unprognostic (2.40e-1)" "unprognostic (1.60e-1)" "unprognostic (2.45e-2)" "unprognostic (4.29e-2)" "unprognostic (7.97e-2)" "potential prognostic unfavorable (8.39e-7)" "unprognostic (1.08e-1)" "unprognostic (7.99e-2)" "unprognostic (2.79e-3)" "unprognostic (4.01e-2)" "unprognostic (2.56e-1)" "unprognostic (6.92e-2)" "potential prognostic unfavorable (5.87e-5)" "unprognostic (3.43e-1)" "unprognostic (1.22e-1)" "unprognostic (9.30e-3)" "unprognostic (1.16e-1)" "unprognostic (2.13e-2)" "unprognostic (1.45e-1)" "unprognostic (2.67e-1)" "unprognostic (3.27e-2)" LYPD4 MGC42718 ENSG00000273111 "LY6/PLAUR domain containing 4" Q6UWN0 19 41837074-41844697 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 314 "testis: 99.5" "Group enriched" "Detected in some" 4 "Late primary spermatocytes: 622.8;Late spermatids: 1505.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Intracellular and membrane" "No annotated function" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" LYPD5 FLJ30469 ENSG00000159871 "LY6/PLAUR domain containing 5" Q6UWN5 19 43785874-43827206 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "skin 1: 48.2" "Cell type enhanced" "Detected in many" "Early spermatids: 36.9;Esophageal apical cells: 130.1;Late primary spermatocytes: 52.0;Late spermatids: 158.5;Syncytiotrophoblasts: 35.6" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 25.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 10.5" "Colon - Enteric glia cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Prostate - Urothelial cells, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Not detected" "Not detected" "HPA042511, HPA054670" Approved Approved Nucleoplasm,Cytosol No NA "Cluster 40: Monocytes - Innate immune response" "Cluster 37: Skin - Keratinization" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 4: Non-specific - Transcription" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 8 "Nucleoplasm, Cytosol" "HPA042511: , HPA054670: " "potential prognostic favorable (7.20e-6)" "unprognostic (7.03e-2)" "unprognostic (1.26e-1)" "unprognostic (4.65e-2)" "unprognostic (1.58e-1)" "unprognostic (6.38e-2)" "unprognostic (4.49e-2)" "unprognostic (2.24e-1)" "unprognostic (1.88e-2)" "potential prognostic favorable (1.83e-5)" "unprognostic (3.04e-2)" "unprognostic (4.80e-3)" "unprognostic (1.33e-2)" "unprognostic (1.91e-1)" "unprognostic (1.02e-1)" "unprognostic (2.70e-1)" "unprognostic (8.25e-2)" "potential prognostic unfavorable (8.16e-4)" "unprognostic (7.15e-2)" "unprognostic (3.47e-1)" "unprognostic (1.14e-1)" "unprognostic (1.18e-2)" "unprognostic (5.96e-2)" "unprognostic (2.20e-1)" "unprognostic (1.92e-1)" "unprognostic (2.37e-1)" LYPD6 MGC52057 ENSG00000187123 "LY6/PLAUR domain containing 6" Q86Y78 2 149329985-149474138 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 10.4;placenta: 14.8" "Cell type enhanced" "Detected in many" "Astrocytes: 63.2;Brain inhibitory neurons: 58.6;Breast hormone-responsive cells: 63.1;Early spermatids: 107.1;Late spermatids: 409.4;Mesothelial cells: 51.3;Papillary tip epithelial cells: 51.1;Pituitary stem cells: 60.1;Undifferentiated spermatogonia: 78.5" "Cell type enhanced" "Detected in many" "LAMP5-LHX6 and Chandelier: 133.3;midbrain-derived inhibitory: 312.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Enteric glia cells, Kidney - Ascending Loop of Henle cells, Pituitary gland - Thyrotropes, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042805 Enhanced Approved Cytosol "Secreted in other tissues" "No annotated function" NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 109: Neurons - Neuronal signaling" 1 Cytosol "HPA042805: " "potential prognostic favorable (8.79e-5)" "unprognostic (3.21e-1)" "unprognostic (1.15e-1)" "unprognostic (3.01e-1)" "validated prognostic favorable (7.22e-4)" "validated prognostic favorable (4.56e-4)" "unprognostic (3.00e-1)" "unprognostic (7.61e-2)" "unprognostic (7.69e-3)" "unprognostic (1.12e-1)" "potential prognostic unfavorable (3.37e-4)" "unprognostic (3.39e-2)" "unprognostic (2.54e-2)" "unprognostic (1.11e-2)" "unprognostic (3.41e-1)" "unprognostic (8.26e-3)" "unprognostic (1.69e-1)" "unprognostic (3.13e-2)" "unprognostic (1.93e-3)" "unprognostic (2.54e-1)" "unprognostic (5.35e-3)" "unprognostic (3.09e-1)" "unprognostic (1.15e-1)" "unprognostic (1.45e-1)" LYPD6B "CT116, LYPD7" ENSG00000150556 "LY6/PLAUR domain containing 6B" Q8NI32 2 149038107-149215262 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 91.9;stomach 1: 39.2" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 189.3;Early spermatids: 275.7;Foveolar cells: 665.4;Late primary spermatocytes: 176.9;Papillary tip epithelial cells: 369.0;Prostatic club cells: 493.6;Prostatic hillock cells: 283.4;Renal collecting duct principal cells: 302.2;Respiratory deuterosomal cells: 203.2;Respiratory ionocytes: 167.6;Respiratory secretory cells: 189.7;Sertoli cells: 163.5;Urothelial cells: 326.1" "Cell type enhanced" "Detected in many" "hippocampal dentate gyrus: 216.9;midbrain-derived inhibitory: 342.1" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 65.2" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 4 "basophil: 13.8" "Lineage enriched" "Detected in many" 4 "granulocytes: 13.8" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA049239 Uncertain "Intracellular and membrane" "No annotated function" NA NA "Cluster 32: Basophils - Transcription" "Cluster 47: Testis - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 68: Foveolar cells - Mucosal defense" "HPA049239: " "unprognostic (5.09e-2)" "unprognostic (1.32e-1)" "unprognostic (6.69e-3)" "unprognostic (9.02e-2)" "unprognostic (1.68e-1)" "unprognostic (4.02e-3)" "unprognostic (2.24e-1)" "unprognostic (7.62e-2)" "unprognostic (3.25e-1)" "unprognostic (4.24e-2)" "unprognostic (4.84e-2)" "unprognostic (5.62e-2)" "unprognostic (2.19e-1)" "unprognostic (2.14e-2)" "unprognostic (6.55e-3)" "unprognostic (5.88e-3)" "unprognostic (2.92e-2)" "unprognostic (3.11e-1)" "unprognostic (2.41e-2)" "unprognostic (2.45e-1)" "unprognostic (5.56e-2)" "unprognostic (1.77e-1)" "unprognostic (8.78e-3)" "unprognostic (2.84e-1)" "unprognostic (2.72e-1)" "unprognostic (1.30e-1)" LYPD8 ENSG00000259823 "LY6/PLAUR domain containing 8" Q6UX82 1 248739415-248755759 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "intestine: 202.5" "Cell type enhanced" "Detected in some" "Colonocytes: 20.9;Distal convoluted tubule cells: 2.9;Enterocytes: 2.3;Goblet cells: 9.6;Loop of henle epithelial cells: 3.9;Proximal tubule cells: 4.5" "Cell type enhanced" "Detected in some" "hippocampal CA4: 1.7;hippocampal dentate gyrus: 1.1;upper-layer intratelencephalic: 1.3" "Group enriched" "Detected in some" 7 "Colon Adenocarcinoma (TCGA): 43.9;Rectum Adenocarcinoma (TCGA): 33.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "colorectal cancer: 1.3;lung cancer: 1.8" "Colon - Colon enterocytes, Kidney - Proximal tubular cells" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to digestive system" "No annotated function" NA NA "Cluster 17: Intestine - Digestion" "Cluster 53: Neurons - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" "unprognostic (1.67e-2)" "unprognostic (3.37e-1)" "unprognostic (7.24e-2)" "unprognostic (4.45e-3)" "unprognostic (1.43e-1)" LYPLA1 "APT-1, LPL1" ENSG00000120992 "Lysophospholipase 1" O75608 8 54046367-54102017 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 974.8;Esophageal apical cells: 886.5;Extravillous trophoblasts: 482.5;Late spermatids: 1093.6;Syncytiotrophoblasts: 543.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050941, HPA063151" Enhanced Approved Nucleoplasm,Cytosol NA NA 280000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 76: Non-specific - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 2 "Nucleoplasm, Cytosol" "HPA050941: , HPA063151: " "unprognostic (3.76e-2)" "unprognostic (5.67e-2)" "unprognostic (3.81e-2)" "unprognostic (4.99e-2)" "unprognostic (5.31e-2)" "unprognostic (2.16e-1)" "unprognostic (3.95e-1)" "unprognostic (8.13e-2)" "unprognostic (7.96e-2)" "unprognostic (1.07e-1)" "potential prognostic favorable (9.38e-4)" "unprognostic (4.46e-2)" "unprognostic (4.91e-2)" "unprognostic (3.83e-2)" "unprognostic (5.23e-2)" "unprognostic (4.49e-3)" "unprognostic (1.49e-1)" "unprognostic (4.08e-2)" "unprognostic (1.04e-2)" "unprognostic (9.71e-2)" "unprognostic (7.54e-3)" "validated prognostic unfavorable (5.24e-4)" "validated prognostic unfavorable (9.32e-4)" "unprognostic (1.56e-1)" "unprognostic (2.62e-2)" "unprognostic (3.63e-1)" "unprognostic (5.54e-3)" "unprognostic (3.06e-2)" "unprognostic (1.74e-1)" "unprognostic (1.39e-2)" "unprognostic (1.30e-1)" LYPLA2 APT-2 ENSG00000011009 "Lysophospholipase 2" O95372 1 23791145-23795539 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 78.0;Epididymal efferent duct ciliated cells: 100.3;Esophageal apical cells: 94.3;Extravillous trophoblasts: 77.7;Megakaryocytes: 74.2;Migrating cytotrophoblasts: 79.8;Syncytiotrophoblasts: 77.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063151 Approved Nucleoplasm,Cytosol NA NA 59000 "Cluster 29: Non-specific - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 3 "Nucleoplasm, Cytosol" "HPA063151: " "unprognostic (4.79e-2)" "unprognostic (5.40e-2)" "unprognostic (3.79e-1)" "unprognostic (2.81e-2)" "unprognostic (5.82e-2)" "unprognostic (2.28e-1)" "unprognostic (1.75e-2)" "unprognostic (1.18e-2)" "unprognostic (2.14e-2)" "unprognostic (2.15e-2)" "unprognostic (1.97e-2)" "unprognostic (5.75e-2)" "unprognostic (1.59e-3)" "potential prognostic unfavorable (6.08e-8)" "unprognostic (1.20e-3)" "unprognostic (1.52e-1)" "unprognostic (7.48e-2)" "unprognostic (1.52e-1)" "unprognostic (1.09e-1)" "unprognostic (1.52e-1)" "unprognostic (4.51e-2)" "unprognostic (4.63e-2)" "unprognostic (1.03e-1)" "unprognostic (1.02e-1)" "unprognostic (2.66e-2)" "unprognostic (1.61e-1)" "unprognostic (5.49e-2)" "unprognostic (7.45e-2)" "unprognostic (3.15e-1)" "unprognostic (1.05e-2)" "unprognostic (6.51e-2)" LYPLAL1 Q96AV0 ENSG00000143353 "Lysophospholipase like 1" Q5VWZ2 1 219173869-219212865 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 476.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045806 Approved Supported Cytosol NA NA 10000 "Cluster 24: Non-specific - Transcription" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 45: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" 4 Cytosol "HPA045806: " "unprognostic (1.37e-1)" "unprognostic (1.21e-1)" "unprognostic (2.07e-1)" "unprognostic (6.23e-2)" "unprognostic (5.51e-2)" "unprognostic (8.98e-3)" "unprognostic (6.40e-2)" "unprognostic (8.67e-2)" "unprognostic (5.06e-2)" "unprognostic (4.76e-2)" "potential prognostic favorable (1.76e-8)" "unprognostic (9.14e-3)" "unprognostic (2.48e-2)" "unprognostic (1.47e-1)" "unprognostic (6.47e-3)" "unprognostic (6.00e-2)" "unprognostic (6.56e-2)" "unprognostic (3.04e-2)" "unprognostic (1.84e-2)" "unprognostic (2.03e-1)" "unprognostic (1.95e-1)" "unprognostic (2.64e-1)" "unprognostic (1.56e-1)" "unprognostic (1.16e-1)" "unprognostic (1.06e-1)" "unprognostic (8.95e-3)" "unprognostic (1.26e-1)" "unprognostic (3.47e-1)" "unprognostic (1.49e-1)" "unprognostic (7.94e-2)" "unprognostic (7.89e-2)" LYRM1 A211C6.1 ENSG00000102897 "LYR motif containing 1" O43325 16 20899868-20925006 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 204.2;Late primary spermatocytes: 198.8;Late spermatids: 779.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 155.4" "Lineage enriched" "Detected in all" 5 "granulocytes: 155.4" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059840 Supported Nucleoplasm,Midbody Yes No "Cluster 32: Basophils - Transcription" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 54: Non-specific - Transcription" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" Nucleoplasm Midbody "HPA059840: " "unprognostic (2.25e-2)" "unprognostic (1.77e-1)" "unprognostic (7.15e-2)" "unprognostic (2.49e-1)" "unprognostic (2.13e-1)" "unprognostic (1.76e-1)" "unprognostic (3.12e-1)" "unprognostic (5.20e-1)" "unprognostic (3.45e-1)" "unprognostic (3.17e-2)" "unprognostic (1.20e-1)" "unprognostic (2.32e-2)" "unprognostic (8.26e-2)" "unprognostic (2.47e-1)" "unprognostic (8.59e-2)" "unprognostic (2.20e-1)" "unprognostic (1.60e-1)" "unprognostic (8.21e-2)" "unprognostic (9.38e-2)" "unprognostic (1.50e-1)" "unprognostic (2.90e-2)" "unprognostic (2.49e-2)" "unprognostic (1.58e-1)" "unprognostic (1.09e-1)" "unprognostic (4.11e-1)" "unprognostic (1.90e-1)" "unprognostic (7.06e-2)" "unprognostic (4.90e-2)" "unprognostic (4.09e-2)" "unprognostic (2.42e-1)" "potential prognostic favorable (6.58e-5)" LYRM2 DJ122O8.2 ENSG00000083099 "LYR motif containing 2" Q9NU23 6 89568144-89638749 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063932 Uncertain Approved Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 22: Non-specific - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 6 Cytosol "HPA063932: " "unprognostic (1.34e-2)" "potential prognostic unfavorable (4.54e-4)" "unprognostic (1.16e-2)" "unprognostic (1.25e-2)" "unprognostic (1.92e-1)" "unprognostic (9.35e-2)" "unprognostic (5.36e-2)" "unprognostic (5.53e-1)" "unprognostic (2.75e-2)" "unprognostic (6.79e-2)" "potential prognostic favorable (4.39e-4)" "unprognostic (2.07e-2)" "unprognostic (2.05e-1)" "unprognostic (2.26e-2)" "unprognostic (6.35e-3)" "unprognostic (3.45e-1)" "unprognostic (8.61e-2)" "unprognostic (1.98e-1)" "unprognostic (6.34e-2)" "potential prognostic favorable (9.55e-4)" "unprognostic (1.21e-1)" "unprognostic (7.96e-2)" "unprognostic (6.19e-2)" "unprognostic (2.58e-1)" "unprognostic (7.02e-3)" "unprognostic (3.36e-1)" "unprognostic (4.60e-2)" "unprognostic (3.54e-2)" "unprognostic (2.92e-1)" "unprognostic (1.60e-1)" "unprognostic (6.10e-2)" LYRM4 "C6orf149, CGI-203, ISD11" ENSG00000214113 "LYR motif containing 4" Q9HD34 6 5103629-5260950 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030362 Approved Supported "Nuclear bodies" NA NA "Cluster 18: Non-specific - Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 53: Neurons - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 82: Dendritic cells - Antigen presentation" 19 "Nuclear bodies" "HPA030362: " "unprognostic (1.45e-1)" "unprognostic (1.16e-1)" "unprognostic (6.78e-2)" "unprognostic (2.84e-2)" "unprognostic (1.05e-2)" "unprognostic (2.60e-1)" "unprognostic (1.63e-1)" "unprognostic (1.42e-3)" "unprognostic (7.96e-2)" "unprognostic (4.02e-2)" "unprognostic (5.51e-2)" "unprognostic (5.81e-2)" "unprognostic (2.75e-2)" "validated prognostic unfavorable (8.39e-5)" "validated prognostic unfavorable (2.71e-4)" "unprognostic (1.42e-1)" "unprognostic (1.63e-1)" "unprognostic (2.30e-2)" "unprognostic (9.14e-2)" "unprognostic (1.27e-1)" "unprognostic (1.33e-2)" "unprognostic (4.08e-1)" "unprognostic (8.26e-3)" "unprognostic (6.48e-2)" "unprognostic (1.80e-1)" "unprognostic (3.60e-2)" "unprognostic (3.17e-2)" "unprognostic (3.54e-2)" "unprognostic (1.49e-1)" "unprognostic (2.09e-2)" "unprognostic (4.57e-2)" LYRM7 "C5orf31, FLJ20796, MZM1L" ENSG00000186687 "LYR motif containing 7" Q5U5X0 5 131170944-131205428 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Chaperone "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 31.5" "Cell type enhanced" "Detected in all" "Early spermatids: 144.7;Late primary spermatocytes: 252.0;Late spermatids: 345.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050053 Approved NA NA "Cluster 24: Non-specific - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 14 "HPA050053: " "unprognostic (2.75e-1)" "unprognostic (4.41e-2)" "unprognostic (3.06e-1)" "unprognostic (1.47e-2)" "unprognostic (5.33e-2)" "unprognostic (1.39e-2)" "unprognostic (2.11e-1)" "unprognostic (1.19e-1)" "unprognostic (5.36e-2)" "unprognostic (1.71e-3)" "potential prognostic favorable (3.53e-8)" "unprognostic (1.09e-2)" "unprognostic (1.30e-1)" "unprognostic (8.53e-3)" "unprognostic (8.45e-2)" "unprognostic (5.24e-2)" "unprognostic (5.28e-2)" "unprognostic (1.64e-1)" "unprognostic (2.13e-1)" "unprognostic (1.79e-2)" "unprognostic (3.95e-3)" "unprognostic (1.95e-1)" "unprognostic (1.27e-2)" "unprognostic (7.18e-2)" "unprognostic (1.19e-2)" "unprognostic (3.32e-1)" "unprognostic (1.78e-2)" "unprognostic (2.09e-1)" "unprognostic (4.65e-1)" "unprognostic (4.71e-3)" "unprognostic (4.81e-2)" LYRM9 "C17orf108, HSD24" ENSG00000232859 "LYR motif containing 9" A8MSI8 17 27878314-27894752 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 3.4;Early primary spermatocytes: 5.3;Epididymal clear cells: 4.1;Fallopian tube ciliated cells: 3.9;Gastric chief cells: 3.3;Hepatic stellate cells: 6.5;Oocytes: 9.2" "Cell type enhanced" "Detected in some" "oligodendrocyte: 4.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023051 Uncertain NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 110: Mural cells - ECM organization" "HPA023051: " "unprognostic (5.50e-2)" "unprognostic (3.01e-1)" "unprognostic (5.59e-2)" "unprognostic (1.37e-1)" "unprognostic (2.90e-1)" "unprognostic (5.55e-2)" "unprognostic (2.62e-2)" "unprognostic (1.39e-2)" "unprognostic (2.21e-2)" "validated prognostic favorable (2.68e-4)" "validated prognostic favorable (1.17e-5)" "potential prognostic favorable (2.39e-8)" "unprognostic (1.47e-3)" "unprognostic (1.39e-3)" "unprognostic (2.31e-3)" "unprognostic (7.62e-2)" "unprognostic (1.07e-2)" "unprognostic (3.82e-2)" "unprognostic (8.99e-2)" "potential prognostic favorable (4.17e-5)" "unprognostic (2.15e-2)" "unprognostic (1.62e-1)" "unprognostic (6.65e-2)" "unprognostic (1.25e-1)" "unprognostic (1.85e-2)" "unprognostic (7.04e-2)" "unprognostic (2.07e-1)" "unprognostic (1.36e-1)" "unprognostic (2.71e-2)" LYSMD1 "MGC35223, RP11-68I18.5, SB145" ENSG00000163155 "LysM domain containing 1" Q96S90 1 151159748-151165948 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 18.4;Cardiomyocytes: 33.8;Cone photoreceptor cells: 16.6;Parietal cells: 15.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028055, HPA064537" Uncertain Enhanced Nucleoplasm NA NA "Cluster 41: Basophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 16: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 11 Nucleoplasm "HPA028055: , HPA064537: " "unprognostic (7.37e-2)" "unprognostic (6.42e-2)" "unprognostic (2.24e-1)" "unprognostic (2.92e-2)" "unprognostic (1.99e-1)" "unprognostic (1.69e-1)" "unprognostic (1.17e-1)" "unprognostic (3.48e-3)" "unprognostic (2.43e-1)" "unprognostic (3.68e-3)" "potential prognostic favorable (9.86e-5)" "unprognostic (2.80e-2)" "unprognostic (8.33e-3)" "unprognostic (5.22e-3)" "unprognostic (4.31e-3)" "unprognostic (1.80e-1)" "unprognostic (3.50e-2)" "potential prognostic favorable (1.01e-4)" "unprognostic (5.74e-2)" "unprognostic (2.07e-1)" "unprognostic (3.03e-1)" "unprognostic (1.36e-1)" "unprognostic (8.51e-2)" "unprognostic (1.08e-1)" "unprognostic (1.07e-2)" "unprognostic (9.44e-3)" "unprognostic (2.11e-1)" "unprognostic (2.20e-1)" "unprognostic (1.46e-1)" "unprognostic (4.84e-3)" "unprognostic (1.71e-1)" LYSMD2 MGC35274 ENSG00000140280 "LysM domain containing 2" Q8IV50 15 51723011-51751585 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 173.8;Late spermatids: 133.6;Neuroendocrine cells: 80.1;pDCs: 97.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040460 Approved Approved "Nuclear bodies,Mitochondria" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 1: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" Mitochondria "Nuclear bodies" "HPA040460: " "unprognostic (1.81e-3)" "unprognostic (3.18e-2)" "unprognostic (8.73e-2)" "unprognostic (2.58e-1)" "unprognostic (1.51e-1)" "unprognostic (1.23e-1)" "unprognostic (3.96e-2)" "unprognostic (1.10e-1)" "unprognostic (7.35e-3)" "unprognostic (3.67e-1)" "unprognostic (1.40e-2)" "unprognostic (7.27e-3)" "potential prognostic unfavorable (3.27e-4)" "unprognostic (2.40e-2)" "unprognostic (1.29e-1)" "unprognostic (1.11e-1)" "unprognostic (7.01e-2)" "unprognostic (7.80e-2)" "unprognostic (3.63e-1)" "unprognostic (4.75e-2)" "unprognostic (6.53e-2)" "unprognostic (3.62e-2)" "unprognostic (1.08e-1)" "unprognostic (4.00e-2)" "unprognostic (1.46e-2)" "unprognostic (2.65e-2)" "unprognostic (4.68e-2)" "unprognostic (2.60e-1)" "unprognostic (1.01e-2)" "unprognostic (1.63e-1)" "unprognostic (2.16e-1)" LYSMD3 FLJ13542 ENSG00000176018 "LysM domain containing 3" Q7Z3D4 5 90515611-90529584 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018024 Approved Approved Cytosol NA NA "Cluster 32: Basophils - Transcription" "Cluster 76: Non-specific - Metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" Cytosol "HPA018024: " "unprognostic (1.36e-3)" "unprognostic (4.12e-3)" "unprognostic (7.78e-2)" "unprognostic (1.11e-2)" "unprognostic (1.24e-2)" "unprognostic (7.35e-2)" "unprognostic (2.16e-1)" "potential prognostic unfavorable (8.60e-4)" "unprognostic (4.42e-2)" "unprognostic (2.37e-3)" "potential prognostic favorable (1.16e-8)" "unprognostic (1.83e-2)" "unprognostic (1.59e-1)" "unprognostic (1.62e-2)" "unprognostic (3.38e-1)" "unprognostic (3.61e-2)" "unprognostic (2.95e-1)" "unprognostic (1.70e-2)" "unprognostic (8.21e-2)" "unprognostic (9.80e-3)" "potential prognostic unfavorable (2.12e-6)" "unprognostic (1.07e-1)" "unprognostic (1.59e-1)" "unprognostic (1.90e-1)" "unprognostic (1.66e-2)" "unprognostic (7.10e-3)" "unprognostic (1.99e-2)" "unprognostic (4.02e-2)" "unprognostic (9.02e-2)" "unprognostic (2.55e-2)" "unprognostic (9.26e-2)" LYSMD4 FLJ33008 ENSG00000183060 "LysM domain containing 4" Q5XG99 15 99715697-99733561 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 72.4;Epicardial cells: 40.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029152, HPA059824" Approved Approved "Actin filaments,Cytosol" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" Cytosol "Actin filaments" "HPA029152: , HPA059824: " "unprognostic (4.93e-2)" "unprognostic (1.67e-1)" "unprognostic (3.50e-2)" "unprognostic (2.83e-1)" "unprognostic (7.08e-2)" "unprognostic (1.84e-1)" "unprognostic (5.19e-3)" "unprognostic (9.55e-2)" "unprognostic (1.08e-1)" "unprognostic (7.46e-2)" "unprognostic (3.93e-2)" "unprognostic (4.61e-3)" "unprognostic (2.38e-2)" "unprognostic (6.50e-3)" "unprognostic (3.08e-2)" "unprognostic (1.05e-1)" "unprognostic (3.16e-1)" "unprognostic (2.42e-1)" "unprognostic (1.19e-2)" "unprognostic (2.37e-1)" "unprognostic (1.71e-2)" "unprognostic (7.80e-2)" "unprognostic (1.92e-1)" "unprognostic (3.72e-1)" "unprognostic (1.27e-2)" "unprognostic (1.58e-1)" "unprognostic (1.54e-1)" "unprognostic (1.12e-1)" "unprognostic (3.34e-1)" "unprognostic (1.45e-1)" "unprognostic (3.86e-1)" LYST "CHS, CHS1, Mauve" ENSG00000143669 "Lysosomal trafficking regulator" Q99698 1 235661041-235883724 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Phagocytosis, Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 97.8" "Cell type enhanced" "Detected in all" "Melanocytes: 779.3;Monocyte progenitors: 1213.5;Neutrophil progenitors: 1647.3;Neutrophils: 1674.5;Rod photoreceptor cells: 597.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 14.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 156.2" "Group enriched" "Detected in all" 9 "granulocytes: 156.2;monocytes: 52.4" "Cancer enhanced" "Detected in all" "skin cancer: 53.4" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053366, HPA055725" Supported "Nucleoplasm,Plasma membrane,Centriolar satellite" Yes No "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 5: Non-specific - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 8 Nucleoplasm "Plasma membrane, Centriolar satellite" "HPA053366: , HPA055725: " "unprognostic (5.36e-2)" "unprognostic (1.45e-1)" "unprognostic (6.68e-2)" "unprognostic (1.02e-1)" "unprognostic (7.98e-2)" "unprognostic (8.80e-2)" "unprognostic (1.12e-1)" "unprognostic (4.95e-2)" "unprognostic (1.37e-1)" "unprognostic (6.01e-2)" "potential prognostic favorable (3.52e-4)" "unprognostic (3.10e-2)" "unprognostic (9.39e-2)" "unprognostic (6.25e-3)" "unprognostic (2.68e-3)" "unprognostic (3.24e-2)" "unprognostic (4.96e-2)" "unprognostic (9.41e-2)" "unprognostic (1.72e-2)" "unprognostic (1.48e-1)" "unprognostic (1.22e-1)" "unprognostic (7.10e-2)" "unprognostic (1.31e-1)" "unprognostic (3.54e-1)" "unprognostic (3.55e-2)" "unprognostic (1.42e-1)" "unprognostic (1.82e-1)" "unprognostic (1.38e-1)" "unprognostic (5.41e-2)" "unprognostic (5.39e-2)" LYVE1 "LYVE-1, XLKD1" ENSG00000133800 "Lymphatic vessel endothelial hyaluronan receptor 1" Q9Y5Y7 11 10556966-10611689 "Plasma proteins, Predicted membrane proteins, Transporters" Transport Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 118.2;placenta: 140.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 1969.3;Kupffer cells: 993.1;Lymphatic endothelial cells: 566.5;Macrophages: 400.6" "Group enriched" "Detected in many" 5 "astrocyte: 56.5;central nervous system macrophage: 60.2;vascular associated smooth muscle cell: 23.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Minor Salivary Gland - Macrophages, Skeletal muscle - Macrophages" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "spinal cord: 2.4" "CAB025860, HPA042953" Supported NA NA 230000000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 23: Choroid plexus - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 21 "CAB025860: , HPA042953: " "unprognostic (1.25e-1)" "unprognostic (6.50e-2)" "unprognostic (7.21e-3)" "unprognostic (1.79e-1)" "unprognostic (1.74e-1)" "unprognostic (2.89e-2)" "unprognostic (6.86e-3)" "unprognostic (8.71e-2)" "unprognostic (2.57e-1)" "unprognostic (1.44e-3)" "potential prognostic favorable (4.97e-4)" "unprognostic (7.06e-2)" "unprognostic (1.30e-1)" "unprognostic (3.62e-2)" "unprognostic (3.54e-2)" "unprognostic (2.32e-1)" "unprognostic (4.37e-2)" "unprognostic (1.16e-1)" "unprognostic (1.79e-3)" "unprognostic (2.64e-1)" "unprognostic (1.33e-1)" "unprognostic (1.52e-1)" "unprognostic (2.01e-1)" "unprognostic (1.71e-1)" "unprognostic (4.94e-2)" "unprognostic (7.59e-2)" "unprognostic (1.50e-1)" LYZ ENSG00000090382 Lysozyme P61626 12 69348381-69354234 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Antimicrobial, Bacteriolytic enzyme, Glycosidase, Hydrolase" "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 9984.7;salivary gland: 21193.7;stomach 1: 8449.1" "Cell type enhanced" "Detected in many" "Breast lactating cells: 12440.3;cDC: 4982.0;Foveolar cells: 3967.9;Lacrimal acinar cells: 57295.4;Monocyte progenitors: 20027.1;monocytes: 6373.8;Mucous neck cells: 10561.1;Paneth cells: 4749.2;Salivary acinar cells: 4181.0;Submucosal glandular cells: 8175.1" "Cell type enriched" "Detected in some" 7 "leukocyte: 94.3" "Cancer enhanced" "Detected in all" "Stomach Adenocarcinoma (TCGA): 2211.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 25283.6;myeloid DC: 14448.9" "Group enriched" "Detected in all" 20 "dendritic cells: 14448.9;monocytes: 25283.6" "Cancer enhanced" "Detected in many" "Gastric cancer: 1810.2;Leukemia: 764.8" "Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Kidney - Macrophages, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Macrophages, Thyroid gland - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB000055, HPA048284, HPA066182" Enhanced Approved "Nucleoplasm,Golgi apparatus,Actin filaments" "Secreted to blood" Enzyme NA NA 1500000000 690000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 60: Stomach - Digestion" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 14 "Golgi apparatus, Actin filaments" Nucleoplasm "CAB000055: , HPA048284: , HPA066182: " "unprognostic (1.99e-1)" "unprognostic (6.26e-2)" "unprognostic (6.69e-2)" "unprognostic (3.06e-2)" "unprognostic (4.65e-1)" "unprognostic (1.59e-1)" "unprognostic (1.24e-2)" "potential prognostic unfavorable (1.41e-4)" "potential prognostic favorable (8.96e-4)" "unprognostic (4.33e-1)" "unprognostic (1.44e-3)" "unprognostic (8.42e-2)" "unprognostic (1.84e-1)" "unprognostic (1.01e-1)" "unprognostic (1.63e-2)" "unprognostic (2.38e-2)" "unprognostic (1.08e-1)" "unprognostic (1.64e-1)" "unprognostic (1.05e-1)" "unprognostic (4.19e-2)" "unprognostic (2.41e-1)" "unprognostic (3.61e-1)" "unprognostic (1.13e-3)" "unprognostic (1.44e-1)" "unprognostic (3.80e-2)" "unprognostic (7.39e-2)" "unprognostic (1.34e-1)" "unprognostic (3.54e-1)" "unprognostic (4.50e-2)" "unprognostic (5.42e-2)" "unprognostic (1.84e-1)" LYZL1 "LYC2, MGC33408" ENSG00000120563 "Lysozyme like 1" Q6UWQ5 10 29289061-29318328 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 438 "testis: 48.7" "Group enriched" "Detected in some" 137 "Early spermatids: 586.0;Late primary spermatocytes: 427.3;Late spermatids: 263.5" "Cell type enriched" "Detected in single" 5 "Bergmann glia: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Secreted in male reproductive system" Enzyme NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" LYZL2 ENSG00000151033 "Lysozyme like 2" Q7Z4W2 10 30611779-30629762 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 685 "testis: 68.4" "Group enriched" "Detected in some" 154 "Early spermatids: 783.8;Late primary spermatocytes: 506.3;Late spermatids: 231.0" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 9 "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 2.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Secreted in male reproductive system" Enzyme NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 27: Breast cancer - Unknown function" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" "unprognostic (3.03e-1)" LYZL4 "LYC4, MGC26768" ENSG00000157093 "Lysozyme like 4" Q96KX0 3 42397083-42410610 "Predicted secreted proteins" Fertilization "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 49 "testis: 49.5" "Group enriched" "Detected in some" 76 "Early spermatids: 374.5;Late primary spermatocytes: 269.5;Late spermatids: 196.4" "Cell type enhanced" "Detected in some" "deep-layer intratelencephalic: 2.8;deep-layer near-projecting: 2.5" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 2.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA038806 Approved Approved "Principal piece,End piece" "Secreted in male reproductive system" Other NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 51: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" "End piece" "Principal piece" "HPA038806: " LYZL6 "LYC1, PRO1485, TKAL754" ENSG00000275722 "Lysozyme like 6" O75951 17 35934518-35943713 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Fertilization "Antimicrobial, Bacteriolytic enzyme, Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 40 "testis: 44.0" "Group enriched" "Detected in some" 5 "Early spermatids: 270.7;Late primary spermatocytes: 182.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA025734, HPA053073" Enhanced "Secreted in male reproductive system" Enzyme NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 15: Non-specific - Transcription" "Cluster 34: Testis cancer - Unknown function" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" "HPA025734: , HPA053073: " LZIC MGC15436 ENSG00000162441 "Leucine zipper and CTNNBIP1 domain containing" Q8WZA0 1 9922113-9943407 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 176.9;Early spermatids: 285.6;Late primary spermatocytes: 345.7;Megakaryocytes: 204.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028184, HPA058614" Approved Approved Nucleoplasm,Cytosol NA NA 310000 "Cluster 29: Non-specific - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 5 Nucleoplasm Cytosol "HPA028184: , HPA058614: " "unprognostic (1.90e-1)" "unprognostic (2.02e-2)" "unprognostic (2.60e-1)" "unprognostic (8.05e-2)" "unprognostic (5.22e-2)" "unprognostic (1.68e-1)" "unprognostic (1.16e-1)" "unprognostic (3.76e-1)" "unprognostic (6.58e-2)" "unprognostic (6.32e-3)" "potential prognostic favorable (1.72e-6)" "unprognostic (1.32e-3)" "unprognostic (2.89e-1)" "validated prognostic unfavorable (2.08e-4)" "validated prognostic unfavorable (3.53e-4)" "unprognostic (2.22e-1)" "unprognostic (2.23e-1)" "unprognostic (2.73e-2)" "unprognostic (2.65e-1)" "unprognostic (4.29e-1)" "unprognostic (9.68e-3)" "unprognostic (1.65e-3)" "unprognostic (1.93e-1)" "unprognostic (2.46e-1)" "unprognostic (2.11e-1)" "unprognostic (1.29e-1)" "potential prognostic unfavorable (3.59e-4)" "unprognostic (9.33e-2)" "unprognostic (6.19e-2)" "unprognostic (7.83e-2)" "unprognostic (2.31e-2)" LZTFL1 BBS17 ENSG00000163818 "Leucine zipper transcription factor like 1" Q9NQ48 3 45823316-45916042 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Epididymal efferent duct ciliated cells: 97.8;Fallopian tube ciliated cells: 106.1;Late primary spermatocytes: 355.8;Respiratory ciliated cells: 121.2;Thymocytes: 141.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043466, HPA048447" Enhanced Supported "Primary cilium,Primary cilium transition zone,Cytosol" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 21: Testis - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 31 Cytosol "Primary cilium, Primary cilium transition zone" "HPA043466: , HPA048447: " "unprognostic (1.91e-2)" "unprognostic (1.41e-2)" "unprognostic (4.77e-2)" "unprognostic (7.97e-2)" "unprognostic (1.99e-1)" "unprognostic (2.56e-1)" "unprognostic (2.51e-1)" "unprognostic (1.54e-2)" "unprognostic (8.04e-2)" "unprognostic (1.02e-2)" "potential prognostic favorable (2.20e-6)" "unprognostic (1.15e-2)" "unprognostic (1.38e-1)" "unprognostic (1.56e-2)" "unprognostic (2.83e-1)" "unprognostic (2.09e-2)" "unprognostic (8.90e-2)" "unprognostic (8.08e-2)" "unprognostic (4.35e-2)" "unprognostic (1.85e-1)" "unprognostic (2.35e-3)" "unprognostic (1.16e-1)" "unprognostic (1.24e-1)" "unprognostic (1.94e-1)" "unprognostic (6.88e-3)" "unprognostic (5.19e-2)" "unprognostic (2.89e-1)" "unprognostic (2.81e-2)" "unprognostic (8.32e-2)" "unprognostic (6.37e-2)" "unprognostic (2.02e-2)" LZTR1 "BTBD29, LZTR-1" ENSG00000099949 "Leucine zipper like transcription regulator 1" Q8N653 22 20982269-20999032 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubule cells: 23.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Pituitary gland - Somatotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067852, HPA068772, HPA071248" Approved Approved Nucleoplasm,Centrosome,Cytosol No No "Cluster 33: Non-specific - ATP binding" "Cluster 74: Non-specific - Signal transduction" "Cluster 45: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 102: Non-specific - Mixed function" 15 Nucleoplasm "Centrosome, Cytosol" "HPA067852: , HPA068772: , HPA071248: " "unprognostic (6.18e-2)" "unprognostic (1.65e-1)" "unprognostic (2.94e-3)" "unprognostic (3.34e-2)" "unprognostic (3.53e-2)" "unprognostic (3.49e-1)" "unprognostic (1.09e-1)" "unprognostic (2.56e-2)" "unprognostic (2.17e-1)" "unprognostic (4.18e-3)" "potential prognostic favorable (1.12e-4)" "unprognostic (6.63e-2)" "unprognostic (2.25e-2)" "unprognostic (1.08e-2)" "unprognostic (3.76e-1)" "unprognostic (9.92e-2)" "unprognostic (5.38e-2)" "unprognostic (1.35e-1)" "unprognostic (1.86e-1)" "unprognostic (6.36e-2)" "unprognostic (1.56e-2)" "unprognostic (2.23e-1)" "unprognostic (1.48e-3)" "unprognostic (3.62e-2)" "unprognostic (3.99e-2)" "unprognostic (1.45e-2)" "unprognostic (6.22e-3)" "unprognostic (4.88e-2)" "unprognostic (8.92e-2)" "unprognostic (8.65e-3)" "unprognostic (2.56e-1)" LZTS1 FEZ1 ENSG00000061337 "Leucine zipper tumor suppressor 1" Q9Y250 8 20246165-20303963 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 24.4;parathyroid gland: 51.0" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 30.5;Breast myoepithelial cells: 29.3;Cytotrophoblasts: 19.8;Melanocytes: 121.3;Pericytes: 92.2;Retinal horizontal cells: 30.1;Rod photoreceptor cells: 59.8;Sertoli cells: 27.6;Thymic myoid cells: 27.2" "Cell type enhanced" "Detected in many" "pericyte: 290.7" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 99.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 58.1" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "amygdala: 32.9;basal ganglia: 95.6;cerebral cortex: 64.6;hippocampal formation: 52.3;olfactory bulb: 38.7" "HPA006294, HPA022046" Approved Approved "Nucleoli,Plasma membrane" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 110: Mural cells - ECM organization" 79 "Plasma membrane" Nucleoli "HPA006294: , HPA022046: " "unprognostic (6.45e-2)" "unprognostic (2.43e-1)" "unprognostic (4.47e-1)" "unprognostic (1.35e-1)" "potential prognostic unfavorable (2.57e-4)" "unprognostic (1.05e-3)" "unprognostic (4.74e-2)" "potential prognostic unfavorable (7.37e-4)" "unprognostic (1.63e-1)" "unprognostic (1.63e-1)" "unprognostic (6.13e-2)" "potential prognostic favorable (1.18e-4)" "unprognostic (1.00e-2)" "unprognostic (1.54e-1)" "unprognostic (7.80e-2)" "unprognostic (2.27e-1)" "unprognostic (8.34e-3)" "unprognostic (3.10e-2)" "unprognostic (2.73e-2)" "unprognostic (1.22e-1)" "potential prognostic unfavorable (2.50e-4)" "unprognostic (4.41e-2)" "unprognostic (2.13e-1)" "unprognostic (4.13e-2)" "unprognostic (9.64e-2)" "unprognostic (5.05e-3)" "unprognostic (8.62e-2)" "unprognostic (5.06e-2)" "unprognostic (4.59e-2)" "unprognostic (1.29e-1)" "unprognostic (4.02e-2)" LZTS2 "KIAA1813, LAPSER1" ENSG00000107816 "Leucine zipper tumor suppressor 2" Q9BRK4 10 100996618-101007836 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 63.3;Tuft cells: 69.2" "Cell type enhanced" "Detected in all" "oligodendrocyte: 83.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Pancreas - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044956 Approved Approved "Plasma membrane,Cytosol" No Yes "Cluster 24: Non-specific - Transcription" "Cluster 74: Non-specific - Signal transduction" "Cluster 11: White matter - Signal transduction" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 62: Smooth muscle cells - Muscle contraction" 256 "Plasma membrane, Cytosol" "HPA044956: " "unprognostic (1.17e-1)" "unprognostic (1.94e-1)" "unprognostic (1.95e-2)" "unprognostic (3.52e-2)" "unprognostic (2.53e-3)" "unprognostic (2.61e-1)" "unprognostic (5.63e-2)" "potential prognostic favorable (7.04e-4)" "unprognostic (2.12e-1)" "unprognostic (3.41e-1)" "unprognostic (4.77e-2)" "unprognostic (1.19e-1)" "unprognostic (1.86e-2)" "unprognostic (6.44e-3)" "unprognostic (1.57e-1)" "unprognostic (3.35e-1)" "unprognostic (2.37e-2)" "unprognostic (3.18e-1)" "unprognostic (5.58e-2)" "unprognostic (1.11e-1)" "unprognostic (2.69e-1)" "unprognostic (1.03e-1)" "unprognostic (6.02e-2)" "unprognostic (2.58e-1)" "unprognostic (1.11e-1)" "unprognostic (1.15e-1)" "unprognostic (2.85e-1)" "unprognostic (3.30e-1)" "unprognostic (1.18e-1)" "unprognostic (2.91e-1)" "unprognostic (1.33e-1)" LZTS3 "KIAA0552, ProSAPiP1" ENSG00000088899 "Leucine zipper tumor suppressor family member 3" O60299 20 3162617-3173549 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 175.2" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 61.4;Brain inhibitory neurons: 52.4;Lacrimal acinar cells: 62.5;Rod photoreceptor cells: 63.6;Salivary acinar cells: 41.4;Salivary duct cells: 41.0;Salivary ionocytes: 52.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Stomach - Chief cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031008, HPA031009" Approved Approved Vesicles NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 53: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 3 Vesicles "HPA031008: , HPA031009: " "potential prognostic favorable (1.95e-4)" "unprognostic (7.93e-2)" "unprognostic (3.55e-1)" "unprognostic (1.04e-2)" "unprognostic (4.91e-2)" "unprognostic (1.48e-1)" "unprognostic (1.12e-2)" "unprognostic (3.53e-3)" "unprognostic (4.71e-1)" "unprognostic (4.75e-2)" "unprognostic (2.18e-2)" "potential prognostic favorable (2.47e-5)" "unprognostic (3.58e-1)" "unprognostic (9.78e-3)" "unprognostic (1.31e-2)" "unprognostic (8.29e-2)" "unprognostic (3.40e-2)" "unprognostic (6.50e-2)" "unprognostic (6.76e-2)" "unprognostic (5.47e-2)" "unprognostic (6.83e-2)" "unprognostic (3.80e-3)" "unprognostic (1.44e-1)" "unprognostic (1.33e-1)" "unprognostic (1.70e-1)" "unprognostic (4.73e-2)" "unprognostic (3.14e-1)" "unprognostic (1.09e-2)" "unprognostic (4.06e-1)" M1AP "C2orf65, D6Mm5e, SPATA37" ENSG00000159374 "Meiosis 1 associated protein" Q8TC57 2 74557883-74648338 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 6.0" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 59.2;Early primary spermatocytes: 87.6;Gonadotrophs: 33.6;Oocytes: 41.4;Renal collecting duct intercalated cells: 21.3;Renal collecting duct principal cells: 27.7;Undifferentiated spermatogonia: 22.7" "Cell type enhanced" "Detected in many" "amygdala excitatory: 16.6;central nervous system macrophage: 18.7" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 6.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "ovarian cancer: 5.1;Rhabdoid: 6.2" "Testis - Spermatocytes" "Not detected" "Not detected" "HPA045420, HPA059302" Uncertain Approved Nucleoli,Mitochondria NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 51: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 3: Early primary spermatocytes - Early meiosis" 11 Mitochondria Nucleoli "HPA045420: , HPA059302: " "unprognostic (2.34e-1)" "unprognostic (3.63e-2)" "unprognostic (2.24e-1)" "unprognostic (1.97e-2)" "unprognostic (3.90e-1)" "unprognostic (1.61e-2)" "unprognostic (4.18e-2)" "unprognostic (2.84e-1)" "unprognostic (1.73e-1)" "unprognostic (5.23e-2)" M6PR "CD-M6PR, CD-MPR" ENSG00000003056 "Mannose-6-phosphate receptor, cation dependent" P20645 12 8940361-8949761 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 118.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034464, HPA040445" Approved NA NA 67000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 21: Non-specific - Metabolism" "Cluster 38: Non-specific - Transcription" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 14 "CAB034464: , HPA040445: " "unprognostic (2.47e-1)" "unprognostic (1.73e-1)" "unprognostic (1.44e-1)" "unprognostic (1.64e-1)" "unprognostic (2.81e-2)" "unprognostic (1.32e-3)" "unprognostic (3.16e-1)" "unprognostic (1.27e-1)" "unprognostic (3.30e-2)" "unprognostic (1.52e-3)" "unprognostic (1.00e-2)" "unprognostic (6.31e-2)" "unprognostic (8.70e-2)" "unprognostic (1.17e-2)" "potential prognostic unfavorable (3.42e-4)" "unprognostic (1.68e-1)" "unprognostic (1.19e-2)" "unprognostic (1.09e-2)" "unprognostic (7.35e-2)" "unprognostic (2.97e-1)" "unprognostic (1.76e-1)" "unprognostic (3.97e-2)" "unprognostic (2.98e-3)" "unprognostic (3.63e-2)" "unprognostic (5.31e-2)" "unprognostic (1.51e-1)" "unprognostic (4.76e-2)" "unprognostic (7.40e-2)" "unprognostic (1.62e-1)" "unprognostic (1.69e-1)" "unprognostic (9.50e-2)" MAB21L1 CAGR1 ENSG00000180660 "Mab-21 like 1" Q13394 13 35473419-35478764 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein, Nucleotidyltransferase, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 30.3;retina: 62.9" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 31.9;Cardiomyocytes: 18.3;Cone photoreceptor cells: 31.1;Müller glia: 152.5;Retinal amacrine cells: 46.9;Retinal bipolar cells: 35.5;Retinal horizontal cells: 36.1;Retinal pigment epithelial cells: 85.3;Rod photoreceptor cells: 93.5;Schwann cells: 21.7" "Cell type enhanced" "Detected in some" "cerebellar inhibitory: 22.5;midbrain-derived inhibitory: 36.8;upper rhombic lip: 31.3" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 1.5" "Region enhanced" "Detected in all" "cerebellum: 47.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 27 "Neuroblastoma: 122.4" "Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells" "Group enriched" "Detected in many" 10 "cerebellum: 40.9;midbrain: 18.6;pons and medulla: 12.4" "Region enhanced" "Detected in all" "cerebellum: 45.2" "HPA049324, HPA059864" Approved Nucleoplasm NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 35: Non-specific - DNA binding" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 11: Muller glia cells - Retinal homeostasis" 3 Nucleoplasm "HPA049324: , HPA059864: " "unprognostic (7.28e-2)" "unprognostic (7.87e-2)" "potential prognostic unfavorable (4.67e-6)" "unprognostic (2.06e-1)" "unprognostic (1.09e-1)" MAB21L2 ENSG00000181541 "Mab-21 like 2" Q9Y586 4 150582151-150584693 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein" "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "intestine: 170.0" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 21.3;Cardiomyocytes: 5.8;Cholangiocytes: 21.2;Choroid plexus epithelial cells: 4.2;Epicardial cells: 9.1;Medullary thymic epithelial cells: 4.8;Müller glia: 4.1;Oocytes: 4.6;Retinal amacrine cells: 10.1;Retinal horizontal cells: 18.0;Retinal pigment epithelial cells: 12.8" "Group enriched" "Detected in some" 6 "choroid plexus epithelial cell: 11.3;lower rhombic lip: 23.9;splatter: 6.2" "Cancer enhanced" "Detected in some" "Colon Adenocarcinoma (TCGA): 5.7;Pancreatic Adenocarcinoma (TCGA): 4.4;Rectum Adenocarcinoma (TCGA): 4.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 10 "Neuroblastoma: 140.1" "Adrenal gland - Adrenal medulla cells" "Group enriched" "Detected in many" 7 "midbrain: 8.0;pons and medulla: 23.4" "Low region specificity" "Detected in all" "HPA049324, HPA059864" Enhanced Nucleoplasm NA NA "Cluster 77: Intestine - Digestion" "Cluster 43: Hindbrain - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 109: Neurons - Neuronal signaling" 24 Nucleoplasm "HPA049324: , HPA059864: " "unprognostic (8.30e-3)" "unprognostic (1.76e-1)" "unprognostic (2.29e-1)" "potential prognostic favorable (8.71e-6)" "unprognostic (2.34e-2)" "unprognostic (1.11e-2)" "unprognostic (3.31e-1)" "unprognostic (1.63e-3)" "unprognostic (7.31e-2)" "unprognostic (5.95e-2)" MAB21L3 "C1orf161, FLJ38716" ENSG00000173212 "Mab-21 like 3" Q8N8X9 1 116111399-116138149 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 14.1;skin 1: 10.0" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 27.7;Cytotrophoblasts: 21.5;Endometrial luminal cells: 39.3;Epididymal clear cells: 44.9;Esophageal apical cells: 88.9;Esophageal suprabasal cells: 33.8;Neutrophils: 41.9;Renal collecting duct intercalated cells: 24.8;Respiratory ionocytes: 38.1;Salivary ionocytes: 120.1;Syncytiotrophoblasts: 35.2" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in many" 4 "Kidney Chromophobe (TCGA): 7.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary gland basal cells, Skin - Keratinocyte (other), Spleen - Neutrophils_2" "Not detected" "Not detected" "Not detected" "Not detected" HPA039551 Approved Nucleoplasm NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 40: Non-specific - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 56: Non-specific - Sensory perception" "Cluster 24: Neutrophils - Innate immunity signal integration" 24 Nucleoplasm "HPA039551: " "potential prognostic unfavorable (4.58e-4)" "unprognostic (3.38e-2)" "unprognostic (9.16e-2)" "unprognostic (1.79e-2)" "unprognostic (3.79e-2)" "unprognostic (9.31e-3)" "unprognostic (1.17e-1)" "unprognostic (2.15e-1)" "unprognostic (3.40e-1)" "unprognostic (9.49e-2)" "unprognostic (1.61e-1)" "unprognostic (2.09e-1)" "unprognostic (1.59e-2)" "unprognostic (1.97e-1)" "potential prognostic favorable (3.62e-4)" "unprognostic (5.04e-2)" "unprognostic (2.58e-1)" MAB21L4 "C2orf54, FLJ22671" ENSG00000172478 "Mab-21 like 4" Q08AI8 2 240886048-240896889 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 56.3;esophagus: 189.6;vagina: 58.4" "Cell type enriched" "Detected in some" 7 "Esophageal apical cells: 1388.4" "Cell type enriched" "Detected in single" 4 "ependymal cell: 1.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 33.5" "Skin - Keratinocyte (other)" "Not detected" "Not detected" "Not detected" "Not detected" HPA052722 Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 84: Apical squamous epithelium - Cornification" 4 "Nucleoplasm, Golgi apparatus" "HPA052722: " "unprognostic (5.79e-2)" "unprognostic (2.28e-3)" "unprognostic (1.59e-1)" "unprognostic (1.04e-2)" "unprognostic (7.23e-2)" "unprognostic (1.03e-2)" "unprognostic (4.66e-2)" "unprognostic (2.54e-2)" "unprognostic (1.45e-2)" "unprognostic (1.91e-1)" "unprognostic (2.37e-1)" "unprognostic (5.76e-2)" "unprognostic (2.59e-2)" "unprognostic (4.93e-2)" "unprognostic (1.42e-2)" "unprognostic (3.93e-1)" "unprognostic (8.34e-3)" "unprognostic (1.60e-1)" "unprognostic (4.36e-1)" "unprognostic (2.53e-1)" "unprognostic (5.80e-3)" "unprognostic (1.13e-1)" "unprognostic (1.41e-1)" "unprognostic (1.26e-1)" "unprognostic (2.97e-2)" MACC1 "7A5, SH3BP4L" ENSG00000183742 "MET transcriptional regulator MACC1" Q6ZN28 7 20134655-20217404 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Growth factor, Mitogen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 11.0" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 671.7;Endometrial glandular cells: 663.8;Endometrial luminal cells: 741.0;Endometrial secretory cells: 1365.8;Epididymal clear cells: 526.7;Epididymal efferent duct ciliated cells: 428.1;Respiratory deuterosomal cells: 458.2;Respiratory secretory cells: 448.8;Salivary duct cells: 457.0;Urothelial cells: 709.3" "Cell type enhanced" "Detected in many" "CGE interneuron: 6.7;leukocyte: 6.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Cholangiocytes, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Ductal cells, Prostate - Urothelial cells, Spleen - B-cells (Spleen)" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA020081, HPA020103, HPA029476, CAB068194" Supported Approved Mitochondria NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 51: Secretory epithelial cells - Mixed function" Mitochondria "CAB068194: , HPA020081: , HPA020103: , HPA029476: " "unprognostic (2.65e-1)" "unprognostic (3.77e-2)" "unprognostic (9.45e-2)" "unprognostic (2.73e-2)" "unprognostic (1.17e-3)" "unprognostic (1.30e-1)" "unprognostic (2.64e-1)" "unprognostic (2.64e-2)" "unprognostic (4.83e-2)" "validated prognostic favorable (2.59e-8)" "validated prognostic favorable (2.52e-5)" "potential prognostic favorable (8.02e-8)" "unprognostic (2.18e-1)" "unprognostic (4.90e-2)" "unprognostic (5.12e-2)" "unprognostic (2.28e-1)" "unprognostic (1.01e-1)" "unprognostic (1.10e-2)" "unprognostic (7.15e-3)" "unprognostic (3.71e-3)" "potential prognostic favorable (8.86e-4)" "unprognostic (1.84e-1)" "unprognostic (4.28e-2)" "unprognostic (5.97e-2)" "unprognostic (1.03e-1)" "unprognostic (2.35e-1)" "unprognostic (6.41e-2)" MACF1 "ABP620, ACF7, FLJ45612, FLJ46776, KIAA0465, KIAA0754, KIAA1251, Lnc-PMIF, MACF" ENSG00000127603 "Microtubule actin crosslinking factor 1" Q9UPN3 1 39081316-39487177 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Wnt signaling pathway" Actin-binding "Disease variant, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ocular epithelial cells: 2163.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Vascular endothelial cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013713, HPA068064, HPA068103" Approved Supported "Plasma membrane,Cell Junctions,Actin filaments,Basal body" NA NA 3500 "Cluster 3: Non-specific - Nuclear processes" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 100: Stratified epithelial cells - Barrier functions" 19 "Plasma membrane, Actin filaments" "Cell Junctions, Basal body" "HPA013713: , HPA068064: , HPA068103: " "unprognostic (2.46e-2)" "unprognostic (6.12e-2)" "unprognostic (5.98e-2)" "unprognostic (2.65e-1)" "unprognostic (2.75e-1)" "unprognostic (3.92e-1)" "unprognostic (7.24e-2)" "unprognostic (1.59e-1)" "unprognostic (2.13e-1)" "unprognostic (2.04e-1)" "potential prognostic favorable (1.67e-5)" "unprognostic (1.84e-2)" "unprognostic (1.68e-2)" "unprognostic (5.64e-3)" "unprognostic (1.02e-1)" "unprognostic (1.20e-1)" "unprognostic (3.07e-2)" "unprognostic (8.56e-2)" "unprognostic (4.14e-2)" "unprognostic (3.14e-1)" "unprognostic (1.82e-1)" "unprognostic (1.13e-1)" "unprognostic (3.51e-3)" "unprognostic (4.16e-1)" "unprognostic (9.16e-2)" "unprognostic (1.82e-2)" "unprognostic (1.10e-1)" "unprognostic (2.89e-1)" "unprognostic (2.38e-1)" "unprognostic (1.88e-1)" "unprognostic (1.44e-1)" MACIR "C5orf30, FLJ25291" ENSG00000181751 "Macrophage immunometabolism regulator" Q96GV9 5 103258763-103278660 "Predicted intracellular proteins" "Cilium biogenesis/degradation, Inflammatory response, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 29.6" "Cell type enhanced" "Detected in many" "Colonocytes: 64.7;Extravillous trophoblasts: 151.4;Mast cells: 61.8;Megakaryocyte-Erythroid progenitors: 63.3;Neutrophil progenitors: 91.2;Neutrophils: 92.7;Platelets: 121.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "basophil: 37.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 37.8" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Spleen - Neutrophils_2, Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043434, HPA060202" Uncertain Approved "Nucleoplasm,Actin filaments,Primary cilium,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 34: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 30 "Nucleoplasm, Actin filaments" "Primary cilium, Cytosol" "HPA043434: , HPA060202: " "unprognostic (4.31e-2)" "unprognostic (1.31e-1)" "potential prognostic unfavorable (6.35e-4)" "unprognostic (1.79e-1)" "unprognostic (2.89e-1)" "unprognostic (3.20e-1)" "unprognostic (4.62e-2)" "unprognostic (3.42e-1)" "unprognostic (2.14e-1)" "potential prognostic favorable (5.26e-4)" "unprognostic (1.02e-1)" "unprognostic (9.21e-3)" "potential prognostic unfavorable (9.29e-6)" "unprognostic (3.63e-2)" "unprognostic (8.89e-2)" "unprognostic (3.65e-1)" "unprognostic (1.80e-1)" "unprognostic (1.27e-1)" "unprognostic (1.01e-1)" "unprognostic (1.63e-2)" "unprognostic (2.17e-2)" "unprognostic (2.10e-1)" "potential prognostic favorable (9.09e-4)" "unprognostic (7.94e-2)" "unprognostic (9.28e-2)" "unprognostic (1.13e-1)" "unprognostic (1.10e-1)" "unprognostic (1.92e-2)" "unprognostic (3.36e-1)" MACO1 "FLJ10747, TMEM57" ENSG00000204178 "Macoilin 1" Q8N5G2 1 25430858-25500209 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 548.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019680 Approved Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - DNA binding" "Cluster 47: Leukemia - Hemostasis" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 30 Cytosol "HPA019680: " "unprognostic (4.98e-2)" "unprognostic (3.97e-3)" "unprognostic (2.76e-1)" "unprognostic (6.39e-2)" "unprognostic (6.08e-2)" "unprognostic (1.46e-1)" "potential prognostic favorable (8.57e-5)" "unprognostic (4.74e-2)" "unprognostic (1.91e-3)" "validated prognostic favorable (7.18e-7)" "validated prognostic favorable (5.67e-4)" "unprognostic (2.53e-2)" "unprognostic (3.94e-2)" "unprognostic (1.26e-3)" "unprognostic (3.16e-1)" "unprognostic (1.89e-1)" "unprognostic (9.30e-2)" "unprognostic (2.51e-1)" "unprognostic (4.56e-2)" "unprognostic (5.83e-2)" "unprognostic (2.06e-1)" "unprognostic (2.53e-1)" "unprognostic (6.03e-2)" "unprognostic (1.45e-1)" "unprognostic (2.14e-2)" "unprognostic (7.05e-2)" "unprognostic (9.15e-2)" "unprognostic (1.01e-1)" "unprognostic (6.94e-3)" MACROD1 LRP16 ENSG00000133315 "Mono-ADP ribosylhydrolase 1" Q9BQ69 11 63998558-64166113 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 270.3" "Cell type enhanced" "Detected in many" "Myonuclei: 327.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041031, HPA071075" Uncertain Supported Nucleoplasm NA NA 8500 "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 24: Neurons - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 15 Nucleoplasm "HPA041031: , HPA071075: " "unprognostic (2.26e-2)" "unprognostic (1.81e-2)" "unprognostic (1.06e-1)" "unprognostic (4.01e-1)" "unprognostic (2.11e-2)" "unprognostic (2.54e-1)" "unprognostic (1.04e-1)" "unprognostic (1.42e-2)" "unprognostic (7.53e-3)" "unprognostic (3.34e-1)" "unprognostic (3.20e-3)" "unprognostic (1.20e-1)" "unprognostic (7.23e-3)" "unprognostic (4.03e-2)" "unprognostic (7.41e-2)" "unprognostic (1.18e-1)" "unprognostic (6.92e-2)" "unprognostic (1.17e-1)" "unprognostic (3.91e-2)" "unprognostic (8.92e-2)" "unprognostic (8.55e-2)" "unprognostic (6.64e-3)" "unprognostic (1.27e-1)" "unprognostic (2.13e-1)" "unprognostic (2.86e-2)" "unprognostic (1.68e-1)" "unprognostic (2.43e-1)" "unprognostic (3.91e-2)" "unprognostic (7.84e-2)" "unprognostic (2.70e-1)" "unprognostic (1.12e-1)" MACROD2 "C20orf133, dJ631M13.5" ENSG00000172264 "Mono-ADP ribosylhydrolase 2" A1Z1Q3 20 13995369-16053197 "Metabolic proteins, Predicted intracellular proteins" "DNA damage" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 6002.6;Brain inhibitory neurons: 2370.3;Corticotrophs: 2219.1;Retinal bipolar cells: 3840.5;Thyrotrophs: 2543.9;Transitional alveolar cells: 5447.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory B-cell: 8.7;naive B-cell: 11.8;neutrophil: 3.6" "Group enriched" "Detected in many" 4 "B-cells: 11.8;granulocytes: 3.6" "Cancer enhanced" "Detected in many" "Kidney cancer: 31.9" "Adipose visceral - Mesothelial cells, Minor Salivary Gland - Minor salivary gland ductal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049076 Enhanced Supported Nucleoplasm,Nucleoli NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 73: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 35: Neurons - Synaptic function & neurogenesis" "Nucleoplasm, Nucleoli" "HPA049076: " "unprognostic (8.53e-3)" "unprognostic (4.77e-2)" "unprognostic (1.05e-1)" "unprognostic (5.32e-3)" "unprognostic (3.19e-3)" "unprognostic (3.06e-1)" "unprognostic (1.57e-1)" "potential prognostic favorable (3.65e-4)" "unprognostic (2.81e-1)" "potential prognostic unfavorable (4.94e-4)" "unprognostic (3.35e-2)" "unprognostic (3.07e-3)" "unprognostic (2.14e-1)" "unprognostic (2.02e-2)" "unprognostic (1.16e-3)" "unprognostic (1.11e-2)" "unprognostic (6.34e-2)" "unprognostic (4.65e-3)" "unprognostic (2.01e-1)" "unprognostic (1.37e-1)" "unprognostic (9.36e-2)" "unprognostic (1.06e-1)" "unprognostic (9.55e-2)" "unprognostic (1.67e-1)" "validated prognostic favorable (5.55e-5)" "validated prognostic favorable (7.17e-4)" "unprognostic (1.88e-2)" "unprognostic (5.98e-2)" "unprognostic (1.40e-1)" "unprognostic (4.29e-1)" "unprognostic (4.63e-2)" MACROH2A1 "H2AFY, macroH2A1.2" ENSG00000113648 "MacroH2A.1 histone" O75367 5 135334381-135399914 "Plasma proteins, Predicted intracellular proteins" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1167.7;Monocyte progenitors: 645.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041189, HPA050962" Supported Supported Nucleoplasm NA NA 4700000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 87 Nucleoplasm "HPA041189: , HPA050962: " "unprognostic (2.15e-2)" "unprognostic (9.76e-3)" "unprognostic (1.84e-1)" "unprognostic (5.72e-2)" "unprognostic (8.95e-2)" "unprognostic (3.61e-1)" "unprognostic (5.23e-3)" "unprognostic (1.21e-1)" "potential prognostic unfavorable (2.97e-4)" "potential prognostic favorable (2.15e-4)" "unprognostic (1.29e-2)" "unprognostic (7.43e-2)" "potential prognostic unfavorable (1.35e-5)" "unprognostic (3.94e-2)" "unprognostic (6.03e-2)" "unprognostic (1.51e-1)" "unprognostic (4.59e-2)" "unprognostic (1.20e-1)" "unprognostic (2.73e-1)" "unprognostic (1.75e-1)" "unprognostic (1.86e-1)" "unprognostic (5.69e-2)" "unprognostic (8.85e-2)" "unprognostic (1.57e-2)" "unprognostic (8.82e-2)" "unprognostic (1.35e-1)" "unprognostic (6.26e-2)" "unprognostic (1.59e-1)" "unprognostic (2.64e-1)" MACROH2A2 H2AFY2 ENSG00000099284 "MacroH2A.2 histone" Q9P0M6 10 70052544-70112282 "Predicted intracellular proteins" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 270.1;Granulosa cells: 93.3;Sertoli cells: 111.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 12.6" "Group enriched" "Detected in many" 8 "dendritic cells: 12.6;monocytes: 5.4" "Cancer enhanced" "Detected in all" "Neuroblastoma: 116.2" "Kidney - Fibroblasts, Skin - Keratinocyte (other), Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035865, HPA041189" Enhanced Supported Nucleoplasm No No 510000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 21: Testis - Mixed function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 89: Adipocytes - Lipid metabolism" 31 Nucleoplasm "HPA035865: , HPA041189: " "potential prognostic favorable (4.96e-4)" "unprognostic (1.54e-1)" "unprognostic (2.32e-1)" "unprognostic (1.67e-1)" "unprognostic (9.58e-2)" "unprognostic (1.37e-2)" "potential prognostic favorable (1.97e-6)" "unprognostic (2.47e-1)" "unprognostic (2.30e-1)" "unprognostic (1.66e-2)" "unprognostic (3.11e-1)" "unprognostic (3.42e-2)" "unprognostic (6.41e-3)" "unprognostic (3.88e-3)" "unprognostic (2.27e-1)" "unprognostic (1.54e-1)" "unprognostic (7.66e-2)" "unprognostic (2.03e-1)" "unprognostic (3.08e-1)" "unprognostic (2.49e-1)" "unprognostic (8.00e-3)" "unprognostic (2.41e-2)" "unprognostic (3.22e-2)" "unprognostic (1.07e-1)" "unprognostic (4.06e-1)" "unprognostic (5.22e-2)" "unprognostic (2.62e-2)" "unprognostic (4.08e-1)" "unprognostic (7.94e-3)" MAD1L1 "HsMAD1, MAD1, PIG9, TP53I9, TXBP181" ENSG00000002822 "Mitotic arrest deficient 1 like 1" Q9Y6D9 7 1815793-2233243 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 62.5;Distal convoluted tubule cells: 47.9;Ependymal cells: 37.5;Late spermatids: 133.8;Loop of henle epithelial cells: 83.0;Microglia: 84.3;Oligodendrocytes: 54.7;Papillary tip epithelial cells: 62.6;Podocytes: 83.9;Proximal tubule cells: 63.5;Renal collecting duct intercalated cells: 68.7;Renal collecting duct principal cells: 72.5;Renal connecting tubule cells: 63.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 115.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003635, CAB015338" Supported Supported "Nucleoplasm,Nuclear membrane" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 67: Non-specific - Unknown function" "Cluster 102: Non-specific - Mixed function" 61 "Nucleoplasm, Nuclear membrane" "CAB015338: , HPA003635: " "unprognostic (3.04e-1)" "unprognostic (1.42e-1)" "unprognostic (2.37e-1)" "unprognostic (3.77e-1)" "unprognostic (1.63e-2)" "unprognostic (2.73e-2)" "unprognostic (9.62e-2)" "unprognostic (1.97e-2)" "unprognostic (6.90e-2)" "unprognostic (1.34e-1)" "unprognostic (1.35e-1)" "unprognostic (1.55e-1)" "potential prognostic favorable (5.71e-4)" "potential prognostic unfavorable (7.62e-5)" "unprognostic (4.04e-2)" "unprognostic (1.08e-1)" "unprognostic (7.29e-2)" "unprognostic (1.22e-1)" "unprognostic (1.61e-1)" "unprognostic (5.98e-3)" "unprognostic (2.38e-2)" "unprognostic (1.03e-1)" "potential prognostic unfavorable (2.00e-4)" "unprognostic (6.58e-2)" "unprognostic (1.24e-1)" "unprognostic (1.65e-2)" "unprognostic (4.56e-2)" "unprognostic (1.10e-1)" "unprognostic (1.33e-2)" "unprognostic (1.72e-1)" "unprognostic (3.53e-1)" MAD2L1 "HSMAD2, MAD2" ENSG00000164109 "Mitotic arrest deficient 2 like 1" Q13257 4 120055623-120066858 "Cancer-related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.5;lymphoid tissue: 5.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 53.8;Differentiating spermatogonia: 86.8;Early primary spermatocytes: 152.2;Enteric transient amplifying cells: 69.5;Erythrocyte progenitors: 91.2;Esophageal basal cells: 77.2;Extravillous trophoblasts: 131.2;Gastric progenitor cells: 55.1;Megakaryocyte progenitors: 84.3;Migrating cytotrophoblasts: 103.1;Monocyte progenitors: 75.2;Oocytes: 156.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003348 Uncertain Approved Nucleoplasm NA Yes 18000 "Cluster 39: T-cells - T-cell receptor" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 2: Neurons - Nucleosome" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Non-specific - Cell proliferation" 76 Nucleoplasm "HPA003348: " "unprognostic (1.65e-1)" "unprognostic (1.50e-2)" "unprognostic (4.75e-2)" "unprognostic (9.06e-2)" "unprognostic (3.42e-2)" "unprognostic (1.09e-1)" "unprognostic (4.69e-2)" "unprognostic (2.49e-2)" "unprognostic (1.98e-1)" "unprognostic (5.27e-3)" "validated prognostic unfavorable (4.86e-4)" "validated prognostic unfavorable (1.11e-4)" "potential prognostic unfavorable (9.46e-9)" "validated prognostic unfavorable (1.98e-4)" "validated prognostic unfavorable (4.54e-5)" "unprognostic (1.42e-1)" "unprognostic (2.63e-1)" "unprognostic (1.08e-1)" "unprognostic (2.38e-2)" "unprognostic (1.45e-2)" "potential prognostic unfavorable (8.77e-4)" "unprognostic (3.95e-3)" "unprognostic (1.14e-2)" "unprognostic (1.97e-2)" "unprognostic (1.14e-1)" "unprognostic (2.05e-1)" "unprognostic (5.55e-2)" MAD2L1BP "CMT2, dJ261G23.1, KIAA0110" ENSG00000124688 "MAD2L1 binding protein" Q15013 6 43629540-43640941 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 55.5;Megakaryocytes: 55.6;Platelets: 98.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028729 Supported "Nucleoplasm,Nuclear membrane,Nucleoli" Yes No "Cluster 33: Non-specific - ATP binding" "Cluster 52: Non-specific - Cellular respiration" "Cluster 23: Choroid plexus - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 65: Non-specific - Cell growth & division" 31 "Nucleoplasm, Nucleoli" "Nuclear membrane" "HPA028729: " "unprognostic (3.93e-2)" "unprognostic (5.11e-2)" "unprognostic (7.41e-2)" "unprognostic (1.84e-1)" "unprognostic (7.72e-2)" "unprognostic (1.96e-1)" "unprognostic (3.21e-2)" "unprognostic (1.81e-2)" "unprognostic (1.56e-1)" "unprognostic (1.29e-2)" "potential prognostic favorable (1.62e-7)" "unprognostic (1.20e-3)" "unprognostic (8.73e-2)" "unprognostic (1.21e-3)" "potential prognostic unfavorable (5.61e-5)" "unprognostic (3.96e-2)" "unprognostic (4.65e-2)" "unprognostic (8.59e-3)" "unprognostic (4.41e-2)" "unprognostic (2.07e-2)" "unprognostic (2.29e-1)" "unprognostic (2.00e-1)" "unprognostic (1.38e-1)" "unprognostic (2.62e-2)" "unprognostic (4.74e-2)" "unprognostic (2.16e-1)" "unprognostic (1.61e-1)" "unprognostic (6.31e-2)" "unprognostic (2.98e-1)" "unprognostic (9.69e-2)" "unprognostic (1.26e-1)" MAD2L2 "FANCV, MAD2B, POLZ2, REV7" ENSG00000116670 "Mitotic arrest deficient 2 like 2" Q9UI95 1 11658918-11691811 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Mitosis, Transcription, Transcription regulation" "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Late spermatids: 941.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003882, CAB008110" Approved Supported Nucleoplasm NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 35: RS4;11 - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 186 Nucleoplasm "CAB008110: , HPA003882: " "unprognostic (4.87e-2)" "unprognostic (3.13e-2)" "unprognostic (6.66e-3)" "unprognostic (1.20e-1)" "unprognostic (1.71e-1)" "unprognostic (4.16e-2)" "unprognostic (3.52e-1)" "unprognostic (1.73e-2)" "unprognostic (1.03e-2)" "potential prognostic unfavorable (5.16e-5)" "unprognostic (2.68e-2)" "unprognostic (1.29e-1)" "unprognostic (1.07e-2)" "validated prognostic unfavorable (5.49e-4)" "validated prognostic unfavorable (5.48e-4)" "unprognostic (1.00e-1)" "unprognostic (4.95e-2)" "unprognostic (4.73e-2)" "unprognostic (1.55e-1)" "unprognostic (1.05e-1)" "unprognostic (1.71e-1)" "unprognostic (1.58e-2)" "unprognostic (9.72e-2)" "unprognostic (2.41e-1)" "unprognostic (7.79e-2)" "potential prognostic favorable (7.42e-4)" "unprognostic (1.46e-1)" "unprognostic (2.96e-2)" "unprognostic (2.26e-1)" "unprognostic (4.54e-2)" "unprognostic (6.92e-2)" MADCAM1 MACAM1 ENSG00000099866 "Mucosal vascular addressin cell adhesion molecule 1" Q13477 19 489176-505343 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 11.7;lymphoid tissue: 13.1" "Cell type enhanced" "Detected in many" "Astrocytes: 22.7;Bergmann glia: 25.6;Epididymal principal cells: 20.7;Müller glia: 20.0;Neutrophils: 23.6;Oligodendrocytes: 19.9" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Pancreatic Adenocarcinoma (TCGA): 4.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "neutrophil: 7.0" "Lineage enriched" "Detected in single" 9 "granulocytes: 7.0" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB075699, HPA077998" Enhanced NA NA 2800000 "Cluster 35: Neutrophils - Protein binding" "Cluster 5: Spleen - Immune response" "Cluster 37: Neurons - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "CAB075699: , HPA077998: " "unprognostic (7.10e-2)" "unprognostic (1.27e-1)" "unprognostic (1.26e-1)" "unprognostic (1.29e-1)" "unprognostic (2.07e-2)" "unprognostic (1.70e-1)" "unprognostic (6.96e-3)" "unprognostic (3.27e-1)" "unprognostic (7.97e-3)" MADD "DENN, KIAA0358, RAB3GEP" ENSG00000110514 "MAP kinase activating death domain" Q8WXG6 11 47269161-47330031 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Guanine-nucleotide releasing factor" "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 101.0" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 180.1;Platelets: 218.8;Retinal horizontal cells: 150.3;Rod photoreceptor cells: 154.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 22.6" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pituitary gland - Lactotropes, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038568 Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 32: Basophils - Transcription" "Cluster 27: Cerebellum - Synaptic function" "Cluster 34: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 8 "Plasma membrane, Cytosol" "HPA038568: " "unprognostic (2.00e-1)" "unprognostic (5.95e-2)" "unprognostic (9.57e-2)" "unprognostic (2.43e-2)" "unprognostic (2.32e-2)" "unprognostic (1.15e-2)" "unprognostic (1.42e-1)" "unprognostic (2.38e-2)" "unprognostic (1.62e-1)" "potential prognostic unfavorable (1.45e-4)" "unprognostic (2.88e-3)" "unprognostic (3.08e-3)" "unprognostic (2.91e-2)" "unprognostic (4.23e-2)" "unprognostic (2.66e-1)" "unprognostic (3.12e-1)" "unprognostic (2.27e-1)" "unprognostic (1.84e-1)" "unprognostic (2.18e-1)" "unprognostic (1.10e-2)" "unprognostic (1.82e-1)" "potential prognostic favorable (2.76e-5)" "unprognostic (7.41e-2)" "unprognostic (2.90e-1)" "unprognostic (3.37e-2)" "unprognostic (2.37e-2)" "unprognostic (9.40e-2)" "unprognostic (2.90e-1)" "unprognostic (1.90e-1)" "unprognostic (2.76e-1)" "unprognostic (3.84e-3)" MAEA "EMP, GID9, HLC-10, p44EMLP" ENSG00000090316 "Macrophage erythroblast attacher, E3 ubiquitin ligase" Q7L5Y9 4 1289887-1340147 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Erythrocyte maturation, Ubl conjugation pathway" "Actin-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 282.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036886, HPA058185" Approved Enhanced Nucleoplasm Yes No "Cluster 7: Non-specific - Innate immune response" "Cluster 70: Non-specific - Protein processing" "Cluster 1: Neurons - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 40 Nucleoplasm "HPA036886: , HPA058185: " "unprognostic (1.00e-1)" "unprognostic (8.05e-3)" "unprognostic (1.65e-1)" "unprognostic (1.17e-2)" "unprognostic (6.00e-3)" "unprognostic (5.98e-2)" "unprognostic (9.17e-2)" "unprognostic (1.93e-2)" "unprognostic (3.84e-3)" "unprognostic (2.86e-1)" "potential prognostic favorable (4.00e-6)" "unprognostic (1.67e-2)" "potential prognostic favorable (4.46e-5)" "potential prognostic unfavorable (1.58e-4)" "unprognostic (7.65e-3)" "unprognostic (6.59e-2)" "unprognostic (7.17e-3)" "unprognostic (8.29e-3)" "unprognostic (4.17e-1)" "unprognostic (1.84e-1)" "unprognostic (3.95e-3)" "unprognostic (8.39e-3)" "unprognostic (5.31e-2)" "unprognostic (2.83e-2)" "unprognostic (5.04e-2)" "unprognostic (1.31e-1)" "unprognostic (3.41e-1)" "unprognostic (4.74e-2)" "unprognostic (1.40e-1)" "unprognostic (2.87e-1)" "unprognostic (6.03e-3)" MAEL "CT128, FLJ14904, SPATA35" ENSG00000143194 "Maelstrom spermatogenic transposon silencer" Q96JY0 1 166975582-167022214 "Predicted intracellular proteins" "Differentiation, Meiosis, RNA-mediated gene silencing, Spermatogenesis" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 24 "testis: 148.8" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 132.8;Early primary spermatocytes: 327.8;Early spermatids: 1466.1;Late primary spermatocytes: 1237.1;Late spermatids: 496.7;Oocytes: 244.1;Undifferentiated spermatogonia: 118.9" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 10.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Gallbladder cancer: 7.6;Myeloma: 9.1;Uterine cancer: 7.2" "Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Testis - Early spermatids" "Region enriched" "Detected in single" 5 "thalamus: 1.1" "Low region specificity" "Detected in some" HPA078602 Approved NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 14: Neurons - Synaptic function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 9 "HPA078602: " "unprognostic (3.44e-1)" "unprognostic (1.33e-1)" "unprognostic (1.89e-2)" "unprognostic (2.49e-1)" "unprognostic (1.81e-1)" "unprognostic (2.79e-2)" "potential prognostic favorable (1.72e-5)" "unprognostic (4.10e-2)" "unprognostic (1.87e-1)" "unprognostic (6.38e-3)" "unprognostic (4.83e-2)" "potential prognostic favorable (1.14e-4)" "unprognostic (3.69e-1)" "unprognostic (2.90e-1)" "unprognostic (3.56e-2)" "unprognostic (2.26e-1)" "unprognostic (2.53e-1)" MAF c-MAF ENSG00000178573 "MAF bZIP transcription factor" O75444 16 79585843-79600737 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Cataract, Deafness, Disease variant, Dwarfism, Intellectual disability, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 301.4;Hofbauer cells: 630.0;Kupffer cells: 904.0;Lymphatic endothelial cells: 374.8;Macrophages: 355.4;Microglia: 512.6" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 651.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 38.1" "Lineage enriched" "Detected in many" 4 "granulocytes: 38.1" "Cancer enriched" "Detected in many" 7 "Myeloma: 58.6" "Breast - Fibroblasts, Kidney - Proximal tubular cells, Skin - Keratinocyte (other), Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010296, HPA028289" Approved Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus,Vesicles" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 77: Intestine - Digestion" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 9 "Nucleoplasm, Nuclear bodies" "Golgi apparatus, Vesicles" "CAB010296: , HPA028289: " "unprognostic (3.33e-2)" "unprognostic (6.56e-2)" "unprognostic (4.42e-1)" "unprognostic (1.59e-2)" "unprognostic (1.40e-1)" "unprognostic (9.44e-2)" "unprognostic (2.75e-3)" "unprognostic (2.98e-2)" "unprognostic (3.23e-3)" "unprognostic (1.62e-2)" "validated prognostic favorable (5.51e-7)" "validated prognostic favorable (9.02e-4)" "unprognostic (2.69e-2)" "unprognostic (6.66e-2)" "potential prognostic favorable (1.91e-4)" "unprognostic (1.21e-1)" "unprognostic (1.77e-2)" "unprognostic (1.10e-1)" "unprognostic (1.56e-1)" "unprognostic (1.38e-2)" "unprognostic (1.87e-1)" "unprognostic (2.26e-1)" "unprognostic (4.44e-3)" "unprognostic (1.68e-1)" "unprognostic (5.25e-2)" "unprognostic (1.09e-2)" "unprognostic (6.49e-2)" "unprognostic (4.55e-2)" "unprognostic (7.65e-2)" "unprognostic (3.94e-1)" "unprognostic (1.66e-1)" MAF1 DKFZp586G1123 ENSG00000179632 "MAF1 homolog, negative regulator of RNA polymerase III" Q9H063 8 144104461-144107611 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 210.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024821, HPA058548, HPA072409" Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 15: Non-specific - Protein processing" 34 Nucleoplasm Cytosol "HPA024821: , HPA058548: , HPA072409: " "unprognostic (1.44e-1)" "unprognostic (7.67e-2)" "unprognostic (1.91e-1)" "potential prognostic unfavorable (7.58e-4)" "unprognostic (4.71e-2)" "unprognostic (2.23e-2)" "unprognostic (6.99e-2)" "unprognostic (2.94e-3)" "unprognostic (8.61e-2)" "unprognostic (2.64e-2)" "unprognostic (6.28e-2)" "unprognostic (5.17e-2)" "unprognostic (1.53e-1)" "potential prognostic unfavorable (3.69e-4)" "unprognostic (3.61e-3)" "unprognostic (2.66e-2)" "unprognostic (4.22e-2)" "unprognostic (1.21e-2)" "unprognostic (4.97e-2)" "unprognostic (1.12e-2)" "unprognostic (3.16e-2)" "unprognostic (3.26e-2)" "unprognostic (1.51e-1)" "unprognostic (1.19e-1)" "unprognostic (3.77e-1)" "unprognostic (2.35e-1)" "unprognostic (1.13e-1)" "unprognostic (2.28e-1)" "unprognostic (2.03e-1)" "unprognostic (1.04e-1)" "unprognostic (1.29e-1)" MAFA "hMafA, RIPE3b1" ENSG00000182759 "MAF bZIP transcription factor A" Q8NHW3 8 143419182-143430732 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "skeletal muscle: 21.9" "Cell type enhanced" "Detected in many" "Endometrial secretory cells: 7.8;Myonuclei: 13.2;Neuroendocrine cells: 19.0;Pancreatic islet cells: 53.7;Thymic myoid cells: 12.2" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 2.8;ependymal cell: 4.3" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 2.5" "Region enhanced" "Detected in many" "spinal cord: 5.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 4.1" "Pancreas - Beta cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 43: Hindbrain - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 3 "unprognostic (4.42e-1)" "unprognostic (6.26e-2)" "unprognostic (2.39e-3)" "unprognostic (1.10e-1)" "unprognostic (7.30e-2)" MAFB KRML ENSG00000204103 "MAF bZIP transcription factor B" Q9Y5Q3 20 40685848-40689236 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 256.8" "Cell type enhanced" "Detected in many" "Breast lactating cells: 312.0;Breast myoepithelial cells: 285.0;Hofbauer cells: 568.0;Kupffer cells: 1002.4;Macrophages: 477.8;monocytes: 651.7;Pancreatic islet cells: 192.9" "Group enriched" "Detected in many" 4 "central nervous system macrophage: 59.7;CGE interneuron: 21.9;LAMP5-LHX6 and Chandelier: 40.1;leukocyte: 23.5;MGE interneuron: 48.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 88.3;non-classical monocyte: 121.9" "Lineage enriched" "Detected in many" 15 "monocytes: 121.9" "Cancer enhanced" "Detected in many" "Bone cancer: 29.3" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Fibroblasts, Colon - Macrophages, Heart muscle - Macrophages, Lung - Macrophages, Pancreas - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Spleen - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA005653 Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Cytosol" Yes NA "Cluster 40: Monocytes - Innate immune response" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 9 Nucleoplasm "Nucleoli, Golgi apparatus, Cytosol" "HPA005653: " "unprognostic (8.92e-3)" "unprognostic (3.64e-1)" "unprognostic (1.94e-1)" "unprognostic (2.92e-2)" "unprognostic (1.79e-2)" "unprognostic (9.15e-3)" "unprognostic (4.66e-2)" "unprognostic (1.96e-1)" "unprognostic (6.05e-2)" "unprognostic (6.40e-2)" "unprognostic (1.00e-1)" "unprognostic (1.23e-1)" "unprognostic (2.91e-2)" "unprognostic (6.52e-2)" "unprognostic (1.24e-3)" "unprognostic (3.08e-1)" "unprognostic (2.20e-3)" "unprognostic (4.38e-1)" "unprognostic (8.04e-3)" "unprognostic (1.94e-2)" "unprognostic (2.73e-2)" "unprognostic (9.30e-3)" "unprognostic (4.86e-2)" "unprognostic (1.32e-1)" "unprognostic (4.22e-2)" "unprognostic (1.06e-2)" "unprognostic (1.28e-1)" "unprognostic (1.48e-1)" "unprognostic (2.40e-3)" "unprognostic (1.15e-2)" "unprognostic (2.42e-1)" MAFF hMafF ENSG00000185022 "MAF bZIP transcription factor F" Q9ULX9 22 38200767-38216507 "Predicted intracellular proteins, Transcription factors" "Stress response, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast secretory cells: 472.2;Endometrial glandular cells: 819.0;Endometrial luminal cells: 687.6;Endometrial secretory cells: 434.0;Epididymal basal cells: 771.6;Esophageal apical cells: 771.1;Syncytiotrophoblasts: 607.3;Urothelial cells: 527.8" "Cell type enhanced" "Detected in many" "endothelial cell: 44.4;vascular associated smooth muscle cell: 22.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 23.9;neutrophil: 8.6;NK-cell: 21.1" "Group enriched" "Detected in many" 6 "granulocytes: 23.9;NK-cells: 21.1" "Cancer enhanced" "Detected in all" "skin cancer: 80.1" "Colon - Neutrophils, Testis - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB025341, HPA055371" Approved Approved Nucleoplasm,Mitochondria No No "Cluster 32: Basophils - Transcription" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 18: Non-specific - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 23 Nucleoplasm Mitochondria "CAB025341: , HPA055371: " "unprognostic (1.51e-1)" "unprognostic (3.17e-3)" "unprognostic (3.43e-2)" "unprognostic (4.91e-3)" "unprognostic (2.97e-2)" "unprognostic (2.07e-2)" "unprognostic (2.86e-2)" "unprognostic (3.50e-2)" "potential prognostic unfavorable (9.05e-4)" "unprognostic (3.03e-1)" "unprognostic (4.02e-1)" "unprognostic (2.14e-3)" "unprognostic (2.48e-1)" "unprognostic (1.28e-2)" "unprognostic (9.48e-2)" "unprognostic (4.12e-3)" "unprognostic (2.70e-1)" "unprognostic (4.28e-2)" "unprognostic (1.25e-1)" "unprognostic (8.93e-3)" "unprognostic (1.66e-1)" "potential prognostic unfavorable (6.66e-4)" "unprognostic (1.06e-1)" "unprognostic (3.07e-1)" "unprognostic (3.25e-2)" "unprognostic (1.68e-3)" "unprognostic (3.76e-2)" "unprognostic (1.52e-1)" "unprognostic (2.17e-1)" "unprognostic (8.88e-2)" "unprognostic (1.97e-1)" MAFG "MGC13090, MGC20149" ENSG00000197063 "MAF bZIP transcription factor G" O15525 17 81918270-81927735 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 162.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 12.3" "Lineage enriched" "Detected in many" 4 "granulocytes: 12.3" "Low cancer specificity" "Detected in all" "Kidney - Macrophages, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025573 Approved NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 7: Liver cancer - Metabolism" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 19 "CAB025573: " "unprognostic (1.31e-1)" "unprognostic (1.83e-2)" "potential prognostic favorable (4.85e-5)" "unprognostic (2.15e-2)" "unprognostic (2.58e-1)" "unprognostic (5.13e-2)" "unprognostic (2.29e-2)" "unprognostic (2.15e-2)" "unprognostic (9.95e-2)" "unprognostic (6.12e-2)" "unprognostic (1.61e-2)" "unprognostic (1.60e-2)" "unprognostic (2.78e-2)" "validated prognostic unfavorable (3.65e-6)" "validated prognostic unfavorable (3.60e-4)" "unprognostic (2.64e-2)" "unprognostic (2.08e-1)" "unprognostic (1.57e-2)" "unprognostic (3.72e-2)" "unprognostic (8.26e-2)" "unprognostic (1.82e-1)" "unprognostic (1.21e-2)" "unprognostic (9.00e-2)" "unprognostic (1.41e-1)" "unprognostic (1.17e-1)" "unprognostic (2.96e-2)" "unprognostic (3.87e-2)" "unprognostic (2.10e-1)" "unprognostic (1.99e-1)" "unprognostic (7.40e-2)" "unprognostic (6.99e-2)" MAFIP "FLJ00219, FLJ35473, FLJ39633, MIP, pp5644, TEKT4P4" ENSG00000274847 "MAFF interacting protein (pseudogene)" Unmapped 53594-115055 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Endometrial glandular cells: 3.6;Gonadotrophs: 4.1;Lactotrophs: 4.4;Medullary thymic epithelial cells: 4.8;Pituicytes/FSCs: 3.6;Somatotrophs: 5.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 30: White matter - Myelination" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 1 MAFK "NFE2U, P18" ENSG00000198517 "MAF bZIP transcription factor K" O60675 7 1530702-1543043 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 123.8;Syncytiotrophoblasts: 112.9;Urothelial cells: 78.7" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 49.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026820, HPA060841" Enhanced Enhanced Nucleoplasm No No "Cluster 22: Eosinophils - Transcription" "Cluster 74: Non-specific - Signal transduction" "Cluster 18: Non-specific - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 11 Nucleoplasm "CAB026820: , HPA060841: " "unprognostic (1.40e-1)" "unprognostic (4.14e-2)" "unprognostic (5.87e-2)" "potential prognostic unfavorable (3.49e-4)" "unprognostic (4.46e-2)" "unprognostic (1.62e-1)" "unprognostic (5.84e-3)" "unprognostic (3.60e-3)" "unprognostic (3.58e-2)" "unprognostic (4.84e-3)" "unprognostic (2.63e-2)" "unprognostic (5.49e-2)" "unprognostic (1.01e-1)" "unprognostic (7.82e-2)" "unprognostic (2.44e-2)" "unprognostic (5.45e-3)" "unprognostic (2.18e-1)" "unprognostic (5.46e-2)" "unprognostic (1.48e-1)" "unprognostic (5.26e-2)" "unprognostic (2.27e-1)" "unprognostic (3.49e-1)" "unprognostic (2.35e-3)" "unprognostic (6.65e-2)" "unprognostic (1.21e-1)" "potential prognostic favorable (7.19e-4)" "unprognostic (4.91e-2)" "unprognostic (3.04e-2)" "unprognostic (2.55e-1)" "unprognostic (1.54e-2)" "unprognostic (1.11e-1)" MAG "GMA, S-MAG, SIGLEC-4A, SIGLEC4A" ENSG00000105695 "Myelin associated glycoprotein" P20916 19 35292125-35313807 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 37 "brain: 699.7" "Cell type enriched" "Detected in some" 5 "Oligodendrocytes: 466.0" "Group enriched" "Detected in many" 34 "committed oligodendrocyte precursor: 230.4;oligodendrocyte: 563.7" "Cancer enriched" "Detected in some" 9 "Glioblastoma Multiforme (TCGA): 39.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 12 "plasmacytoid DC: 2.9" "Lineage enriched" "Detected in single" 12 "dendritic cells: 2.9" "Cancer enriched" "Detected in single" 8 "skin cancer: 7.6" "Region enhanced" "Detected in all" "white matter: 2743.6" "Low region specificity" "Detected in all" "CAB009345, HPA012499" Enhanced Approved "Equatorial segment,Perinuclear theca" NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 69: Skin cancer - ECM organization" "Cluster 80: Oligodendrocytes - Myelination" 1 "Equatorial segment, Perinuclear theca" "CAB009345: , HPA012499: " "unprognostic (1.30e-1)" "unprognostic (3.60e-2)" "unprognostic (2.20e-1)" "unprognostic (1.57e-1)" "unprognostic (7.24e-2)" "unprognostic (9.19e-2)" "unprognostic (9.26e-2)" "unprognostic (3.90e-1)" "unprognostic (8.40e-2)" MAGEA1 "CT1.1, MAGE1, MGC9326" ENSG00000198681 "MAGE family member A1" P43355 X 153179284-153183880 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Tumor antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 44 "testis: 4.4" "Group enriched" "Detected in some" 32 "Differentiating spermatogonia: 28.9;Early primary spermatocytes: 43.0;Undifferentiated spermatogonia: 17.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Lung Squamous Cell Carcinoma (TCGA): 12.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 66.3" "Testis - Spermatocytes, Testis - Spermatogonia" CAB002620 Enhanced Supported Cytosol NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 39 Cytosol "CAB002620: " "unprognostic (1.61e-3)" "unprognostic (5.38e-2)" "unprognostic (3.53e-1)" "unprognostic (1.36e-1)" "unprognostic (1.29e-1)" "unprognostic (9.26e-2)" "unprognostic (3.32e-2)" "unprognostic (8.08e-3)" "unprognostic (3.24e-1)" "unprognostic (1.26e-1)" "unprognostic (1.43e-1)" "unprognostic (7.87e-2)" "unprognostic (2.53e-1)" "unprognostic (4.56e-1)" "unprognostic (5.52e-2)" "unprognostic (2.44e-1)" "unprognostic (4.42e-1)" MAGEA10 "CT1.10, MAGE10, MGC10599" ENSG00000124260 "MAGE family member A10" P43363 X 152133310-152138578 "Predicted intracellular proteins" "Tumor antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "placenta: 8.9;testis: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 9.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Spermatocytes" "Region enhanced" "Detected in some" "thalamus: 1.8" "HPA003333, HPA070780" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 9: Non-specific - Receptor signaling" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 89: Adipocytes - Lipid metabolism" 5 Nucleoplasm Cytosol "HPA003333: , HPA070780: " "unprognostic (1.87e-1)" "unprognostic (1.37e-2)" "unprognostic (1.16e-1)" "unprognostic (2.06e-1)" "unprognostic (2.89e-1)" "unprognostic (5.16e-2)" "unprognostic (1.05e-2)" "unprognostic (1.34e-2)" "unprognostic (2.60e-3)" "unprognostic (7.28e-2)" "unprognostic (5.62e-2)" "unprognostic (1.65e-1)" "unprognostic (2.04e-2)" MAGEA11 "CT1.11, MAGE-11, MAGE11, MAGEA-11, MGC10511" ENSG00000185247 "MAGE family member A11" P43364 X 149688228-149717268 "Predicted intracellular proteins" "Tumor antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "epididymis: 19.9" "Group enriched" "Detected in some" 4 "Early primary spermatocytes: 48.3;Epididymal principal cells: 56.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Lung Squamous Cell Carcinoma (TCGA): 8.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Spermatocytes, Testis - Spermatogonia" HPA052687 Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" 75 "Nucleoplasm, Nuclear bodies" Cytosol "HPA052687: " "unprognostic (1.63e-2)" "unprognostic (4.63e-2)" "unprognostic (4.51e-1)" "unprognostic (3.31e-1)" "unprognostic (5.43e-2)" "unprognostic (1.68e-1)" "unprognostic (2.15e-1)" "unprognostic (4.27e-2)" "unprognostic (8.00e-2)" "unprognostic (2.47e-3)" "unprognostic (4.87e-1)" MAGEA12 "CT1.12, MAGE12" ENSG00000213401 "MAGE family member A12" P43365 X 152733757-152737669 "Predicted intracellular proteins" "Tumor antigen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "testis: 2.7" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 18.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Spermatogonia" NA NA "Cluster 67: Testis - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" 17 "unprognostic (5.58e-3)" "unprognostic (2.23e-1)" "unprognostic (1.73e-1)" "unprognostic (1.11e-1)" "unprognostic (1.72e-2)" "unprognostic (1.50e-1)" "unprognostic (4.43e-1)" "potential prognostic unfavorable (2.38e-4)" "unprognostic (1.40e-1)" "unprognostic (4.91e-2)" "unprognostic (2.73e-1)" "unprognostic (1.07e-1)" "unprognostic (1.10e-1)" "unprognostic (3.52e-1)" "unprognostic (1.67e-1)" "unprognostic (1.78e-1)" "unprognostic (1.49e-2)" "unprognostic (2.75e-1)" MAGEA2 "CT1.2, MAGE2, MAGEA2A" ENSG00000268606 "MAGE family member A2" P43356 X 152749863-152753884 "Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Tumor antigen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 36 "testis: 3.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 75.8" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" 33 "unprognostic (5.59e-2)" "unprognostic (3.00e-1)" "unprognostic (6.91e-2)" "unprognostic (1.03e-1)" "unprognostic (2.30e-1)" "unprognostic (1.61e-1)" "potential prognostic unfavorable (2.41e-5)" "unprognostic (1.50e-1)" "unprognostic (6.85e-2)" "unprognostic (1.99e-1)" "unprognostic (7.54e-3)" "unprognostic (2.59e-1)" "unprognostic (7.31e-2)" "unprognostic (4.46e-2)" "unprognostic (3.27e-1)" "unprognostic (5.72e-2)" MAGEA2B "MAGE2, MAGEA2, MGC16973" ENSG00000183305 "MAGE family member A2B" P43356 X 152714586-152718607 "Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Tumor antigen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 13 "testis: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 5.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" 31 "unprognostic (2.37e-1)" "unprognostic (3.12e-1)" "unprognostic (2.48e-1)" "unprognostic (6.51e-1)" "unprognostic (8.70e-3)" "unprognostic (8.91e-2)" "unprognostic (1.59e-1)" "unprognostic (3.38e-1)" "unprognostic (4.25e-3)" MAGEA3 "CT1.3, HIP8, HYPD, MAGE3, MGC14613" ENSG00000221867 "MAGE family member A3" P43357 X 152698767-152702347 "Cancer-related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Tumor antigen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 25 "testis: 7.6" "Group enriched" "Detected in some" 9 "Differentiating spermatogonia: 42.8;Early primary spermatocytes: 55.1;Undifferentiated spermatogonia: 32.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Spermatogonia" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 25 "unprognostic (5.35e-3)" "unprognostic (5.02e-1)" "unprognostic (2.55e-1)" "unprognostic (7.46e-2)" "unprognostic (9.31e-2)" "unprognostic (2.40e-1)" "unprognostic (5.04e-2)" "potential prognostic unfavorable (2.63e-4)" "unprognostic (2.92e-1)" "unprognostic (5.94e-2)" "unprognostic (3.00e-1)" "unprognostic (7.93e-2)" "unprognostic (1.36e-2)" "unprognostic (4.73e-1)" "unprognostic (8.94e-3)" "unprognostic (2.94e-1)" "unprognostic (1.35e-3)" "unprognostic (2.83e-1)" "unprognostic (1.32e-2)" MAGEA4 "CT1.4, MAGE-41, MAGE-X2, MAGE4, MAGE4A, MAGE4B, MGC21336" ENSG00000147381 "MAGE family member A4" P43358 X 151912495-151925171 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Tumor antigen" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 20.7" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 18.0;Differentiating spermatogonia: 223.0;Early primary spermatocytes: 74.4;Extravillous trophoblasts: 18.7;Gastric progenitor cells: 16.7;Migrating cytotrophoblasts: 21.1;Syncytiotrophoblasts: 37.6;Undifferentiated spermatogonia: 127.9" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Lung Squamous Cell Carcinoma (TCGA): 94.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 204.6" "Testis - Spermatogonia" "HPA021942, CAB040535" Enhanced Approved "Nuclear speckles,Cytosol" NA NA 14000 "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 51 "Nuclear speckles" Cytosol "CAB040535: , HPA021942: " "potential prognostic unfavorable (1.79e-4)" "unprognostic (2.03e-2)" "unprognostic (9.49e-2)" "unprognostic (3.57e-2)" "unprognostic (2.08e-2)" "unprognostic (8.04e-2)" "unprognostic (2.08e-1)" "unprognostic (9.73e-3)" "unprognostic (3.65e-2)" "unprognostic (1.29e-1)" "unprognostic (2.73e-1)" "unprognostic (9.34e-2)" "unprognostic (3.87e-1)" "unprognostic (5.12e-2)" "unprognostic (1.48e-1)" "unprognostic (2.30e-2)" MAGEA6 "CT1.6, MAGE-3b, MAGE3B, MAGE6" ENSG00000197172 "MAGE family member A6" P43360 X 152766136-152769716 "Cancer-related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Tumor antigen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 22 "testis: 7.0" "Group enriched" "Detected in some" 17 "Differentiating spermatogonia: 35.8;Early primary spermatocytes: 44.0;Undifferentiated spermatogonia: 31.0" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Spermatogonia" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 63 "unprognostic (8.47e-3)" "unprognostic (3.88e-1)" "unprognostic (1.03e-1)" "unprognostic (1.21e-2)" "unprognostic (2.54e-2)" "unprognostic (1.43e-1)" "unprognostic (2.36e-2)" "potential prognostic unfavorable (1.88e-4)" "unprognostic (1.08e-1)" "unprognostic (1.91e-1)" "unprognostic (1.26e-1)" "unprognostic (8.14e-2)" "unprognostic (4.25e-2)" "unprognostic (1.43e-1)" "unprognostic (6.62e-3)" "unprognostic (6.45e-2)" "unprognostic (5.25e-3)" "unprognostic (2.60e-1)" "unprognostic (4.87e-2)" MAGEA8 "CT1.8, MAGE8, MGC2182" ENSG00000156009 "MAGE family member A8" P43361 X 149881141-149885835 "Predicted intracellular proteins" "Tumor antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "placenta: 12.5" "Group enriched" "Detected in some" 4 "Cytotrophoblasts: 88.4;Extravillous trophoblasts: 41.2;Migrating cytotrophoblasts: 62.8;Syncytiotrophoblasts: 85.7" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder Urothelial Carcinoma (TCGA): 2.6" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "thyroid cancer: 8.1" "Testis - Spermatocytes" HPA003998 Enhanced NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 37: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 23 "HPA003998: " "unprognostic (6.12e-3)" "unprognostic (3.46e-1)" "unprognostic (2.11e-1)" "unprognostic (4.43e-1)" MAGEA9 "CT1.9, MAGE9, MGC8421" ENSG00000123584 "MAGE family member A9" P43362 X 149781930-149787737 "Predicted intracellular proteins" "Tumor antigen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 38 "testis: 3.8" "Cell type enriched" "Detected in single" 4 "Early primary spermatocytes: 2.2" "Cancer enhanced" "Detected in some" "Lung Squamous Cell Carcinoma (TCGA): 6.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Esophageal cancer: 3.8;lymphoma: 5.7;Myeloma: 4.1;Sarcoma: 4.2" "HPA045401, HPA051687" Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 3: Early primary spermatocytes - Early meiosis" 8 "Nucleoplasm, Golgi apparatus" "HPA045401: , HPA051687: " "unprognostic (1.82e-1)" "unprognostic (5.27e-2)" "unprognostic (1.68e-1)" "unprognostic (4.10e-1)" "unprognostic (2.65e-1)" "unprognostic (7.22e-3)" MAGEA9B ENSG00000267978 "MAGE family member A9B" P43362 X 149581653-149587459 "Predicted intracellular proteins" "Tumor antigen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 31 "testis: 9.5" "Cell type enriched" "Detected in some" 6 "Early primary spermatocytes: 48.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 14.9;Lung Squamous Cell Carcinoma (TCGA): 25.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "HPA045401, HPA051687" Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 55: Lymphoma - Immune response" "Cluster 3: Early primary spermatocytes - Early meiosis" 5 "Nucleoplasm, Golgi apparatus" "HPA045401: , HPA051687: " "unprognostic (3.27e-2)" "unprognostic (1.81e-1)" "unprognostic (1.97e-2)" "unprognostic (4.58e-1)" "unprognostic (3.15e-1)" "unprognostic (2.20e-2)" "unprognostic (4.84e-2)" "unprognostic (3.34e-2)" "unprognostic (9.55e-2)" "unprognostic (4.45e-2)" "unprognostic (7.11e-3)" "unprognostic (9.64e-3)" MAGEB1 "CT3.1, DAM10, MAGE-Xp, MAGEL1, MGC9322" ENSG00000214107 "MAGE family member B1" P43366 X 30243715-30252040 "Predicted intracellular proteins" "Tumor antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 29 "testis: 14.4" "Group enriched" "Detected in some" 6 "Differentiating spermatogonia: 9.6;Early primary spermatocytes: 16.7;Epididymal principal cells: 5.4;Oocytes: 4.6;Sertoli cells: 13.6;Undifferentiated spermatogonia: 17.9" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 9 "Testicular Germ Cell Tumor (TCGA): 13.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 16.0;lymphoma: 10.4;Myeloma: 9.3" "Testis - Sertoli cells" "HPA001193, HPA002820" Enhanced NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 55: Lymphoma - Immune response" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" "HPA001193: , HPA002820: " "unprognostic (1.36e-1)" "unprognostic (3.66e-1)" "unprognostic (1.93e-1)" MAGEB10 FLJ32965 ENSG00000177689 "MAGE family member B10" Q96LZ2 X 27807990-27823014 "Predicted intracellular proteins" "Tumor antigen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "testis: 2.3" "Group enriched" "Detected in some" 4 "Differentiating spermatogonia: 12.6;Early primary spermatocytes: 11.0" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Spermatocytes, Testis - Spermatogonia" "Not detected" "Not detected" HPA000611 Uncertain NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 48: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 11 "HPA000611: " "unprognostic (1.99e-1)" "unprognostic (5.63e-2)" MAGEB16 ENSG00000189023 "MAGE family member B16" A2A368 X 35798342-35803772 "Predicted intracellular proteins" "Tumor antigen" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 31 "testis: 3.0" "Group enriched" "Detected in some" 14 "Differentiating spermatogonia: 4.8;Early primary spermatocytes: 10.5;Oocytes: 9.2;Undifferentiated spermatogonia: 17.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Testicular Germ Cell Tumor (TCGA): 2.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "Myeloma: 4.3" "Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" "HPA055743, HPA076456" Uncertain Approved Nucleoplasm,Centrosome NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 20: Myeloma - Immune response" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 1 Nucleoplasm Centrosome "HPA055743: , HPA076456: " "unprognostic (3.24e-1)" MAGEB17 ENSG00000182798 "MAGE family member B17" A8MXT2 X 16167481-16171464 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 4 "pancreas: 1.9;testis: 1.6" "Group enriched" "Detected in some" 5 "Early primary spermatocytes: 10.1;Retinal pigment epithelial cells: 4.3" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Colon Adenocarcinoma (TCGA): 6.2;Liver Hepatocellular Carcinoma (TCGA): 1.9;Rectum Adenocarcinoma (TCGA): 5.0;Testicular Germ Cell Tumor (TCGA): 4.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 4.2" "Prostate - Prostate glandular cells, Testis - Spermatocytes" HPA003756 Uncertain Uncertain Nucleoplasm NA NA "Cluster 21: Testis - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 3: Early primary spermatocytes - Early meiosis" Nucleoplasm "HPA003756: " "unprognostic (1.39e-1)" "unprognostic (1.26e-1)" "unprognostic (1.79e-1)" "unprognostic (3.33e-2)" "unprognostic (1.82e-3)" "unprognostic (2.20e-2)" "unprognostic (2.57e-1)" MAGEB18 MGC33889 ENSG00000176774 "MAGE family member B18" Q96M61 X 26138343-26140736 "Predicted intracellular proteins" "Ubl conjugation pathway" "Tumor antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Early primary spermatocytes: 1.8;Late primary spermatocytes: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA046141 Enhanced NA NA "Cluster 51: Myeloma - Immunoglobulins" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 17 "HPA046141: " MAGEB2 "CT3.2, DAM6, MAGE-XP-2, MGC26438" ENSG00000099399 "MAGE family member B2" O15479 X 30215563-30220089 "Predicted intracellular proteins" "Ubl conjugation pathway" "Tumor antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 60 "testis: 27.2" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 53.5;Early primary spermatocytes: 33.4;Oocytes: 119.7;Undifferentiated spermatogonia: 136.3" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "Testicular Germ Cell Tumor (TCGA): 49.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 66.2" "Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" "HPA065224, HPA074544, HPA075519" Enhanced Approved Cytosol NA Yes "Cluster 57: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 190 Cytosol "HPA065224: , HPA074544: , HPA075519: " "potential prognostic unfavorable (2.61e-5)" "unprognostic (1.93e-2)" "unprognostic (4.54e-3)" "unprognostic (2.57e-3)" "unprognostic (2.80e-1)" "unprognostic (1.12e-1)" "unprognostic (5.40e-1)" "unprognostic (3.89e-1)" "unprognostic (3.21e-1)" "unprognostic (1.08e-1)" "unprognostic (1.12e-1)" MAGEB3 CT3.5 ENSG00000198798 "MAGE family member B3" O15480 X 30230657-30237495 "Predicted intracellular proteins" "Tumor antigen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 108 "epididymis: 16.7;testis: 4.7" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 10.6;Differentiating spermatogonia: 6.3;Early primary spermatocytes: 18.6;Epididymal principal cells: 21.6;Sertoli cells: 13.0;Undifferentiated spermatogonia: 3.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 9 "testis cancer: 1.2" "Testis - Sertoli cells" "Not detected" "Not detected" HPA072203 Approved NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 20: Myeloma - Immune response" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" 2 "HPA072203: " MAGEB4 "CT3.6, MGC33144" ENSG00000120289 "MAGE family member B4" O15481 X 30242000-30244187 "Predicted intracellular proteins" "Tumor antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 101 "epididymis: 25.7;testis: 8.3" "Group enriched" "Detected in some" 20 "Epididymal principal cells: 3.0;Sertoli cells: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Sertoli cells" HPA030456 Enhanced NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 42 "HPA030456: " MAGEB5 "CT3.3, MAGE-B5" ENSG00000188408 "MAGE family member B5" Q9BZ81 X 26216169-26218270 "Cancer-related genes, Predicted intracellular proteins" "Tumor antigen" "Cancer-related genes" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 20 "Early spermatids: 5.5;Late primary spermatocytes: 5.9;Late spermatids: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" HPA052627 Uncertain NA NA "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" "HPA052627: " MAGEB6 "CT3.4, FLJ40242, MAGE-B6, MAGEB6A" ENSG00000176746 "MAGE family member B6" Q8N7X4 X 26192440-26195646 "Cancer-related genes, Predicted intracellular proteins" "Tumor antigen" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 30 "testis: 3.0" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 9.6;Early primary spermatocytes: 29.8;Late primary spermatocytes: 6.1;Undifferentiated spermatogonia: 8.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Testicular Germ Cell Tumor (TCGA): 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Spermatocytes, Testis - Spermatogonia" "HPA041853, HPA076711" Enhanced NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 3: Early primary spermatocytes - Early meiosis" 12 "HPA041853: , HPA076711: " "unprognostic (6.19e-2)" MAGEB6B MAGEB6P1 ENSG00000232030 "MAGE family member B6B" X 26160601-26162410 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 11 "Early primary spermatocytes: 5.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Spermatocytes" NA NA "Cluster 51: Myeloma - Immunoglobulins" "Cluster 3: Early primary spermatocytes - Early meiosis" MAGEC1 "CT7, CT7.1, MAGE-C1, MGC39366" ENSG00000155495 "MAGE family member C1" O60732 X 141903894-141909374 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Tumor antigen" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 45 "testis: 7.1" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 4.4;Early primary spermatocytes: 22.7;Oocytes: 4.6;Undifferentiated spermatogonia: 12.1" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Skin Cutaneous Melanoma (TCGA): 13.2;Testicular Germ Cell Tumor (TCGA): 5.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 29.3" "Testis - Spermatogonia" "HPA004622, CAB015452" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 3: Early primary spermatocytes - Early meiosis" 4 "Nucleoplasm, Cytosol" "CAB015452: , HPA004622: " "potential prognostic unfavorable (9.12e-4)" "unprognostic (2.97e-3)" "unprognostic (9.27e-2)" "unprognostic (7.32e-2)" "unprognostic (7.42e-2)" "unprognostic (6.52e-2)" "unprognostic (1.17e-1)" "unprognostic (2.47e-1)" "unprognostic (1.03e-1)" "unprognostic (2.17e-3)" "unprognostic (9.33e-2)" MAGEC2 "CT10, HCA587, MAGE-C2, MAGEE1" ENSG00000046774 "MAGE family member C2" Q9UBF1 X 142202342-142205290 "Cancer-related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Tumor antigen" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 184 "testis: 18.4" "Group enriched" "Detected in some" 75 "Differentiating spermatogonia: 61.4;Early primary spermatocytes: 111.4;Undifferentiated spermatogonia: 72.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 33.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 60.2;thyroid cancer: 51.5" "Testis - Spermatogonia" HPA062230 Enhanced Supported Nucleoplasm,Cytosol Yes NA "Cluster 6: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 19 Nucleoplasm Cytosol "HPA062230: " "unprognostic (4.78e-2)" "unprognostic (2.11e-1)" "unprognostic (5.37e-1)" "unprognostic (7.18e-2)" "unprognostic (6.90e-2)" "unprognostic (3.41e-2)" "unprognostic (7.08e-1)" "unprognostic (3.20e-2)" "unprognostic (5.56e-2)" "unprognostic (4.60e-1)" "unprognostic (1.14e-3)" "unprognostic (3.19e-1)" "unprognostic (2.53e-1)" "unprognostic (4.57e-1)" "unprognostic (8.66e-2)" "unprognostic (6.86e-2)" MAGEC3 "CT7.2, HCA2, MAGE-C3" ENSG00000165509 "MAGE family member C3" Q8TD91 X 141838316-141897832 "Cancer-related genes, Predicted intracellular proteins" "Tumor antigen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "blood vessel: 2.0;brain: 3.6" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 10.6;Brain excitatory neurons: 12.5;Brain inhibitory neurons: 13.1;Differentiating spermatogonia: 5.0;Oligodendrocytes: 34.4;Other brain neurons: 8.5;Pituitary stem cells: 5.1;Somatotrophs: 10.7;Thyrotrophs: 9.2;Undifferentiated spermatogonia: 11.6" "Cell type enhanced" "Detected in many" "oligodendrocyte: 51.7" "Cancer enhanced" "Detected in single" "Testicular Germ Cell Tumor (TCGA): 1.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 2.2;thyroid cancer: 2.7" "Adipose subcutaneous - Smooth muscle cells" HPA052067 Approved NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 46: Skeletal myocytes - Muscle structure & formation" "HPA052067: " "unprognostic (1.84e-1)" "unprognostic (1.51e-1)" MAGED1 "DLXIN-1, NRAGE" ENSG00000179222 "MAGE family member D1" Q9Y5V3 X 51803007-51902354 "Cancer-related genes, Predicted intracellular proteins" "Biological rhythms, Ubl conjugation pathway" "Tumor antigen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 425.4;Sertoli cells: 480.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Fibroblasts, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043645 Approved Cytosol NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 65: Brain - Transcription" "Cluster 23: Choroid plexus - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 114 Cytosol "HPA043645: " "unprognostic (1.46e-1)" "unprognostic (7.73e-3)" "unprognostic (1.58e-1)" "unprognostic (1.09e-1)" "unprognostic (2.16e-1)" "unprognostic (1.21e-1)" "unprognostic (1.36e-1)" "unprognostic (9.66e-2)" "unprognostic (1.55e-1)" "unprognostic (7.46e-2)" "unprognostic (3.81e-3)" "potential prognostic unfavorable (4.24e-6)" "unprognostic (3.33e-2)" "unprognostic (5.72e-3)" "unprognostic (2.27e-3)" "unprognostic (5.15e-2)" "unprognostic (1.21e-2)" "unprognostic (1.02e-1)" "unprognostic (6.94e-2)" "unprognostic (2.63e-1)" "unprognostic (3.77e-2)" "unprognostic (1.23e-2)" "unprognostic (1.55e-1)" "unprognostic (1.42e-1)" "unprognostic (1.43e-1)" "unprognostic (2.45e-1)" "unprognostic (2.43e-1)" "unprognostic (1.88e-3)" "unprognostic (1.20e-1)" "potential prognostic unfavorable (2.84e-4)" "unprognostic (6.74e-2)" MAGED2 "11B6, BCG1, HCA10, JCL-1, MAGE-D2, MAGED, MGC8386" ENSG00000102316 "MAGE family member D2" Q9UNF1 X 54807599-54816015 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Tumor antigen" "Bartter syndrome, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 314.7;Granulosa cells: 752.6;Ovarian stromal cells: 337.6;Peritubular myoid cells: 278.5;Platelets: 332.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "testis cancer: 403.0" "Adipose visceral - Adipose progenitor cells, Breast - Breast glandular cells, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "HPA031572, HPA031573" Approved Enhanced Nucleoplasm,Nucleoli,Cytosol No No 33000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 75: Ovary - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 108: Fibroblasts - ECM organization" 26 "Nucleoplasm, Nucleoli, Cytosol" "HPA031572: , HPA031573: " "unprognostic (1.07e-1)" "unprognostic (1.49e-1)" "unprognostic (4.62e-2)" "unprognostic (4.92e-1)" "unprognostic (1.84e-1)" "unprognostic (4.51e-2)" "unprognostic (3.78e-3)" "unprognostic (2.10e-2)" "unprognostic (1.33e-1)" "unprognostic (7.88e-2)" "potential prognostic favorable (2.21e-5)" "unprognostic (9.27e-2)" "unprognostic (1.31e-2)" "potential prognostic unfavorable (6.35e-4)" "unprognostic (9.11e-3)" "unprognostic (3.74e-1)" "unprognostic (1.10e-1)" "unprognostic (5.56e-3)" "unprognostic (5.47e-1)" "unprognostic (1.07e-3)" "unprognostic (5.57e-1)" "potential prognostic favorable (6.13e-4)" "unprognostic (1.43e-1)" "unprognostic (2.02e-1)" "unprognostic (2.59e-1)" "unprognostic (9.23e-2)" "unprognostic (2.00e-1)" "unprognostic (2.97e-2)" "unprognostic (1.43e-1)" "unprognostic (1.49e-1)" "unprognostic (4.98e-2)" MAGED4 "KIAA1859, MAGE-E1, MAGE1, MGC3210" ENSG00000154545 "MAGE family member D4" Q96JG8 X 52184876-52192268 "Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Tumor antigen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.0;ovary: 14.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 8.3;T-reg: 5.3" "Group enriched" "Detected in many" 53 "B-cells: 8.3;dendritic cells: 3.0;T-cells: 5.3" "Cancer enhanced" "Detected in many" "testis cancer: 50.3" HPA003554 Uncertain NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 65: Brain - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 98: Neurons - Neurotransmission & signaling" 4 "HPA003554: " "unprognostic (2.57e-1)" "unprognostic (1.56e-1)" "unprognostic (7.07e-3)" "unprognostic (2.58e-1)" "unprognostic (3.57e-1)" "unprognostic (1.97e-3)" "unprognostic (2.39e-1)" "unprognostic (3.95e-2)" MAGED4B ENSG00000187243 "MAGE family member D4B" Q96JG8 X 52061827-52069219 "Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Tumor antigen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 43.8;pituitary gland: 17.5" "Cell type enhanced" "Detected in some" "Oligodendrocyte progenitor cells: 1.2;Other brain neurons: 1.6" "Cell type enhanced" "Detected in single" "oligodendrocyte precursor cell: 1.4" "Cancer enriched" "Detected in many" 5 "Glioblastoma Multiforme (TCGA): 53.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 4.6" "Group enriched" "Detected in many" 22 "B-cells: 2.3;dendritic cells: 4.6;T-cells: 2.2" "Cancer enhanced" "Detected in many" "testis cancer: 16.7" HPA003554 Approved NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 65: Brain - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 98: Neurons - Neurotransmission & signaling" 4 "HPA003554: " "unprognostic (4.15e-2)" "unprognostic (3.10e-2)" "unprognostic (9.33e-2)" "unprognostic (2.39e-2)" "unprognostic (4.80e-2)" "unprognostic (1.46e-1)" "unprognostic (3.82e-2)" "unprognostic (3.51e-2)" "unprognostic (7.24e-2)" "validated prognostic unfavorable (1.28e-4)" "validated prognostic unfavorable (2.22e-5)" "unprognostic (3.99e-3)" "unprognostic (1.74e-2)" "unprognostic (3.39e-2)" "unprognostic (4.67e-2)" "unprognostic (3.27e-2)" "potential prognostic favorable (8.67e-4)" "unprognostic (1.51e-1)" "unprognostic (4.11e-2)" "potential prognostic favorable (6.31e-4)" "unprognostic (2.57e-3)" "unprognostic (2.85e-1)" "unprognostic (8.76e-2)" "unprognostic (2.72e-2)" "unprognostic (8.01e-2)" "potential prognostic unfavorable (1.13e-5)" "unprognostic (1.60e-1)" "unprognostic (7.53e-3)" "unprognostic (2.17e-2)" MAGEE1 "DAMAGE, KIAA1587" ENSG00000198934 "MAGE family member E1" Q9HCI5 X 76427710-76431342 "Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Tumor antigen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 25.0" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 31.9;Brain excitatory neurons: 16.1;Brain inhibitory neurons: 15.9;Corticotrophs: 10.4;Other brain neurons: 24.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" HPA003047 Approved Approved "Cytokinetic bridge,Cytosol" Yes No "Cluster 24: Non-specific - Transcription" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 1: Neurons - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 98: Neurons - Neurotransmission & signaling" 22 Cytosol "Cytokinetic bridge" "HPA003047: " "unprognostic (5.33e-2)" "unprognostic (1.43e-2)" "unprognostic (2.34e-1)" "unprognostic (3.80e-2)" "unprognostic (1.03e-1)" "unprognostic (5.33e-3)" "unprognostic (9.46e-2)" "unprognostic (1.57e-2)" "potential prognostic favorable (4.58e-6)" "unprognostic (3.61e-3)" "unprognostic (2.29e-1)" "unprognostic (1.69e-2)" "unprognostic (1.47e-2)" "unprognostic (6.35e-2)" "unprognostic (2.11e-3)" "unprognostic (1.68e-1)" "unprognostic (2.45e-1)" "potential prognostic favorable (1.77e-4)" "unprognostic (3.02e-1)" "unprognostic (5.07e-2)" "unprognostic (4.61e-2)" "unprognostic (1.25e-1)" "unprognostic (1.30e-1)" "unprognostic (2.16e-1)" "unprognostic (1.15e-1)" MAGEE2 HCA3 ENSG00000186675 "MAGE family member E2" Q8TD90 X 75782987-75785254 "Predicted intracellular proteins" "Tumor antigen" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 4.1" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 1.2;Epicardial cells: 2.3;Other brain neurons: 1.9" "Low cell type specificity" "Detected in some" "Cancer enriched" "Detected in single" 9 "Glioblastoma Multiforme (TCGA): 1.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030625 Uncertain NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 98: Neurons - Neurotransmission & signaling" 3 "HPA030625: " "unprognostic (1.40e-1)" "unprognostic (1.30e-3)" MAGEF1 ENSG00000177383 "MAGE family member F1" Q9HAY2 3 184710364-184712064 "Predicted intracellular proteins" "Ubl conjugation pathway" "Tumor antigen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 124.1;Hofbauer cells: 129.7;Respiratory ionocytes: 127.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Mitotic cells (Stomach), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "HPA046899, HPA054190" Uncertain Approved "Actin filaments" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 20: Pituitary gland - Hormone signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 63: Non-specific - Protein processing" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 12 "Actin filaments" "HPA046899: , HPA054190: " "unprognostic (1.20e-1)" "unprognostic (1.99e-1)" "unprognostic (4.88e-2)" "unprognostic (3.43e-2)" "unprognostic (2.99e-2)" "unprognostic (2.27e-2)" "unprognostic (3.96e-2)" "unprognostic (1.03e-1)" "unprognostic (7.37e-3)" "unprognostic (3.73e-3)" "unprognostic (1.49e-3)" "unprognostic (1.03e-1)" "unprognostic (2.83e-1)" "validated prognostic unfavorable (5.28e-4)" "validated prognostic unfavorable (8.55e-5)" "unprognostic (3.20e-2)" "unprognostic (2.59e-2)" "unprognostic (3.55e-2)" "potential prognostic favorable (4.91e-5)" "unprognostic (4.08e-2)" "unprognostic (2.37e-1)" "unprognostic (4.63e-1)" "unprognostic (7.02e-2)" "unprognostic (4.86e-2)" "unprognostic (8.92e-2)" "unprognostic (1.62e-1)" "unprognostic (1.15e-1)" "unprognostic (6.21e-2)" "unprognostic (1.13e-1)" "unprognostic (5.71e-2)" "unprognostic (6.76e-3)" MAGEH1 APR1 ENSG00000187601 "MAGE family member H1" Q9H213 X 55452127-55453566 "Predicted membrane proteins" "Tumor antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "epididymis: 487.2" "Group enriched" "Detected in many" 7 "Epididymal clear cells: 336.8;Epididymal principal cells: 972.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Myeloma: 57.6" "Kidney - Fibroblasts, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011324, HPA011971" Uncertain Supported "Nucleoli,Nucleoli rim" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 22: Epididymis - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 8 "Nucleoli, Nucleoli rim" "HPA011324: , HPA011971: " "unprognostic (1.27e-2)" "unprognostic (5.96e-2)" "unprognostic (3.26e-2)" "unprognostic (2.10e-1)" "unprognostic (1.56e-1)" "unprognostic (2.44e-1)" "unprognostic (1.24e-2)" "potential prognostic favorable (9.44e-5)" "unprognostic (4.71e-2)" "unprognostic (1.07e-1)" "potential prognostic favorable (1.70e-8)" "unprognostic (1.84e-2)" "unprognostic (4.38e-2)" "unprognostic (8.47e-3)" "unprognostic (1.36e-3)" "unprognostic (2.24e-3)" "unprognostic (2.94e-1)" "unprognostic (1.03e-1)" "unprognostic (3.91e-3)" "unprognostic (1.26e-2)" "unprognostic (3.51e-1)" "potential prognostic favorable (2.12e-4)" "unprognostic (3.02e-1)" "unprognostic (6.10e-2)" "unprognostic (1.95e-1)" "unprognostic (8.11e-2)" "unprognostic (2.39e-1)" "potential prognostic unfavorable (3.45e-4)" "unprognostic (2.30e-1)" "unprognostic (2.76e-2)" "unprognostic (3.06e-3)" MAGEL2 "NDNL1, nM15" ENSG00000254585 "MAGE family member L2" Q9UJ55 15 23643549-23647867 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation, Transport, Ubl conjugation pathway" Repressor "Autism spectrum disorder, Intellectual disability, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 14.6;pituitary gland: 8.3" "Group enriched" "Detected in some" 4 "Brain inhibitory neurons: 9.2;Other brain neurons: 23.8" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 5.8" "Region enriched" "Detected in many" 4 "hypothalamus: 54.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Sarcoma: 1.2;testis cancer: 2.1" "Pituitary gland - Somatotropes, Stomach - Fibroblasts" "Region enhanced" "Detected in many" "hypothalamus: 17.7" NA NA "Cluster 65: Brain - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 98: Neurons - Neurotransmission & signaling" 10 "unprognostic (8.60e-2)" "unprognostic (1.14e-1)" "unprognostic (2.98e-2)" MAGI1 "AIP3, BAIAP1, BAP1, MAGI-1, TNRC19, WWP3" ENSG00000151276 "Membrane associated guanylate kinase, WW and PDZ domain containing 1" Q96QZ7 3 65353525-66038918 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 2121.6;Renal collecting duct intercalated cells: 8162.6;Retinal horizontal cells: 2414.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Spleen - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031851, HPA031853, HPA077002" Supported Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 64: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 47: Leukemia - Hemostasis" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 31 "Cell Junctions" Nucleoplasm "HPA031851: , HPA031853: , HPA077002: " "unprognostic (5.66e-3)" "unprognostic (1.84e-1)" "unprognostic (9.52e-2)" "unprognostic (1.63e-1)" "unprognostic (6.51e-2)" "unprognostic (1.35e-1)" "unprognostic (2.13e-1)" "unprognostic (1.18e-2)" "unprognostic (1.67e-2)" "unprognostic (9.66e-2)" "validated prognostic favorable (9.05e-6)" "validated prognostic favorable (1.41e-4)" "unprognostic (6.81e-3)" "unprognostic (9.25e-3)" "unprognostic (5.95e-3)" "unprognostic (1.09e-2)" "unprognostic (2.37e-2)" "unprognostic (1.35e-1)" "unprognostic (1.22e-2)" "unprognostic (1.98e-1)" "unprognostic (7.04e-3)" "unprognostic (2.14e-1)" "unprognostic (6.90e-2)" "unprognostic (1.55e-2)" "unprognostic (3.65e-3)" "unprognostic (1.39e-1)" "unprognostic (4.64e-2)" "unprognostic (1.76e-1)" "unprognostic (3.12e-2)" "unprognostic (2.39e-3)" MAGI2 "ACVRIP1, AIP1, ARIP1, KIAA0705, MAGI-2" ENSG00000187391 "Membrane associated guanylate kinase, WW and PDZ domain containing 2" Q86UL8 7 78017055-79453667 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Endocytosis, Neurogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.9" "Cell type enriched" "Detected in many" 8 "Podocytes: 40893.6" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 4 "Glioblastoma Multiforme (TCGA): 22.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 5.5" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013650 Approved NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 57: Podocytes - Glomerular filtration" 7 "HPA013650: " "unprognostic (2.03e-1)" "unprognostic (4.10e-2)" "unprognostic (6.04e-2)" "unprognostic (6.85e-2)" "unprognostic (1.29e-2)" "unprognostic (2.15e-1)" "unprognostic (2.51e-1)" "unprognostic (7.79e-3)" "unprognostic (3.73e-3)" "unprognostic (2.15e-3)" "unprognostic (6.17e-3)" "unprognostic (1.02e-3)" "unprognostic (2.83e-1)" "unprognostic (8.41e-2)" "unprognostic (2.89e-1)" "unprognostic (1.85e-1)" "unprognostic (8.03e-2)" "unprognostic (3.63e-1)" "unprognostic (6.42e-2)" "unprognostic (1.99e-1)" "unprognostic (2.75e-2)" "unprognostic (2.12e-2)" "unprognostic (1.83e-1)" "unprognostic (1.78e-2)" "unprognostic (6.57e-2)" "unprognostic (4.76e-3)" "unprognostic (1.29e-1)" MAGI3 MAGI-3 ENSG00000081026 "Membrane associated guanylate kinase, WW and PDZ domain containing 3" Q5TCQ9 1 113390515-113685923 "Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 32.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 1287.9;Renal collecting duct intercalated cells: 1059.8;Transitional alveolar cells: 1217.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Lung - Alveolar cells type 1, Spleen - Endothelial cells, Stomach - Gastric mucous cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008444 Supported "Cell Junctions" NA NA "Cluster 42: Retina - Visual perception" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 15 "Cell Junctions" "HPA008444: " "unprognostic (3.26e-1)" "unprognostic (8.92e-2)" "unprognostic (9.05e-3)" "unprognostic (2.86e-1)" "potential prognostic favorable (8.00e-4)" "unprognostic (1.86e-1)" "unprognostic (4.20e-2)" "unprognostic (3.31e-3)" "unprognostic (2.79e-3)" "unprognostic (3.26e-2)" "validated prognostic favorable (3.99e-7)" "validated prognostic favorable (8.74e-5)" "unprognostic (4.21e-1)" "unprognostic (2.54e-1)" "unprognostic (8.74e-2)" "unprognostic (7.87e-3)" "unprognostic (2.90e-1)" "unprognostic (1.80e-1)" "unprognostic (5.98e-2)" "unprognostic (2.14e-2)" "unprognostic (3.64e-1)" "unprognostic (2.19e-2)" "unprognostic (1.57e-1)" "unprognostic (1.81e-1)" "unprognostic (4.82e-3)" "unprognostic (1.34e-2)" "unprognostic (2.23e-2)" "unprognostic (8.06e-2)" "unprognostic (2.72e-1)" "unprognostic (2.21e-1)" "unprognostic (3.03e-2)" MAGIX "FLJ21687, JM10, PDZX" ENSG00000269313 "MAGI family member, X-linked" Q9H6Y5 X 49162564-49168774 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 19.0" "Cell type enhanced" "Detected in many" "Breast lactating cells: 128.6;Epididymal efferent duct ciliated cells: 42.4;Fallopian tube ciliated cells: 66.4;Megakaryocytes: 43.3;Respiratory ciliated cells: 50.2;Tuft cells: 57.6" "Cell type enhanced" "Detected in many" "ependymal cell: 15.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 4.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA007390, HPA035302" Uncertain Approved "Nucleoplasm,Mitotic chromosome" Yes NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 70: Non-specific - Protein processing" "Cluster 35: Non-specific - DNA binding" "Cluster 27: Breast cancer - Unknown function" "Cluster 4: Breast lactating luminal cells - Lactation" Nucleoplasm "Mitotic chromosome" "HPA007390: , HPA035302: " "unprognostic (1.05e-3)" "unprognostic (5.35e-2)" "unprognostic (1.65e-1)" "unprognostic (6.86e-2)" "unprognostic (8.11e-3)" "unprognostic (1.92e-1)" "unprognostic (1.19e-3)" "potential prognostic favorable (3.02e-4)" "unprognostic (2.63e-2)" "potential prognostic favorable (1.22e-6)" "unprognostic (3.30e-1)" "potential prognostic favorable (1.32e-5)" "unprognostic (1.90e-1)" "unprognostic (4.43e-2)" "potential prognostic favorable (8.91e-4)" "unprognostic (8.19e-2)" "unprognostic (3.00e-1)" "unprognostic (5.35e-2)" "unprognostic (1.90e-2)" "unprognostic (4.77e-2)" "unprognostic (2.64e-2)" "unprognostic (2.87e-2)" "unprognostic (2.48e-1)" "unprognostic (2.17e-1)" "unprognostic (4.65e-3)" "unprognostic (2.00e-1)" "unprognostic (6.02e-2)" "unprognostic (6.38e-2)" MAGOH "MAGOH1, MAGOHA" ENSG00000162385 "Mago homolog, exon junction complex subunit" P61326 1 53226900-53238518 "Essential proteins, Predicted intracellular proteins, Transporters" "mRNA processing, mRNA splicing, mRNA transport, Nonsense-mediated mRNA decay, Translation regulation, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 280.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015425, HPA043036, HPA047754" Approved Supported Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 21: Non-specific - Metabolism" "Cluster 37: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 64 Nucleoplasm "CAB015425: , HPA043036: , HPA047754: " "unprognostic (7.00e-2)" "unprognostic (1.13e-2)" "unprognostic (6.00e-2)" "unprognostic (7.57e-2)" "unprognostic (2.35e-2)" "unprognostic (1.64e-2)" "unprognostic (1.83e-1)" "unprognostic (2.00e-1)" "unprognostic (1.12e-1)" "unprognostic (1.14e-2)" "unprognostic (4.12e-2)" "unprognostic (1.61e-1)" "unprognostic (5.87e-2)" "unprognostic (1.74e-3)" "potential prognostic unfavorable (2.38e-5)" "unprognostic (1.34e-1)" "unprognostic (2.76e-2)" "unprognostic (7.52e-2)" "unprognostic (1.09e-1)" "unprognostic (2.04e-2)" "unprognostic (6.30e-2)" "unprognostic (4.58e-3)" "unprognostic (2.90e-1)" "unprognostic (4.43e-2)" "unprognostic (7.20e-3)" "unprognostic (5.81e-2)" "unprognostic (8.90e-2)" "unprognostic (4.49e-2)" "unprognostic (1.38e-1)" "unprognostic (5.52e-2)" "unprognostic (2.03e-2)" MAGOHB "FLJ10292, MGN2" ENSG00000111196 "Mago homolog B, exon junction complex subunit" Q96A72 12 10604193-10613609 "Predicted intracellular proteins" "mRNA processing, mRNA splicing, mRNA transport, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 145.8;Gastric progenitor cells: 116.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043036, HPA047754" Uncertain NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 22: Epididymis - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 27: Non-specific - Cell proliferation" 63 "HPA043036: , HPA047754: " "unprognostic (1.69e-2)" "unprognostic (6.01e-3)" "unprognostic (6.73e-2)" "unprognostic (1.93e-1)" "unprognostic (1.52e-1)" "unprognostic (1.76e-1)" "unprognostic (1.51e-2)" "unprognostic (1.51e-1)" "unprognostic (3.66e-2)" "unprognostic (1.63e-2)" "potential prognostic unfavorable (2.99e-8)" "unprognostic (1.98e-2)" "unprognostic (1.05e-1)" "unprognostic (9.56e-3)" "unprognostic (2.53e-3)" "potential prognostic unfavorable (3.42e-4)" "unprognostic (8.23e-3)" "unprognostic (1.17e-1)" "unprognostic (6.23e-2)" "potential prognostic favorable (1.65e-5)" "unprognostic (2.06e-1)" "unprognostic (7.57e-3)" "potential prognostic unfavorable (4.75e-4)" "unprognostic (1.76e-1)" "unprognostic (1.57e-1)" "unprognostic (2.65e-1)" "unprognostic (5.02e-3)" "potential prognostic favorable (8.21e-4)" "unprognostic (3.74e-1)" "unprognostic (4.87e-2)" "unprognostic (2.06e-1)" MAGT1 "DKFZp564K142, IAP, MRX95, OST3B, SLC58A1" ENSG00000102158 "Magnesium transporter 1" Q9H0U3 X 77825747-77899271 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epididymal principal cells: 300.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049851 Approved "Intracellular and membrane" Transport NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 22: Epididymis - Mixed function" "Cluster 30: White matter - Myelination" "Cluster 36: Non-specific - mRNA processing" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 62 "HPA049851: " "unprognostic (5.71e-2)" "unprognostic (1.19e-3)" "unprognostic (2.97e-1)" "unprognostic (2.22e-2)" "unprognostic (3.05e-2)" "unprognostic (8.22e-2)" "unprognostic (9.16e-2)" "potential prognostic unfavorable (3.95e-4)" "unprognostic (2.58e-2)" "unprognostic (1.36e-3)" "potential prognostic favorable (5.37e-8)" "unprognostic (2.67e-1)" "unprognostic (2.60e-1)" "unprognostic (8.19e-2)" "unprognostic (1.63e-3)" "unprognostic (6.98e-2)" "unprognostic (6.95e-2)" "unprognostic (8.59e-2)" "unprognostic (2.81e-1)" "unprognostic (6.15e-2)" "unprognostic (3.47e-3)" "unprognostic (3.49e-3)" "unprognostic (2.34e-2)" "unprognostic (7.69e-2)" "unprognostic (1.09e-1)" "unprognostic (3.08e-2)" "unprognostic (9.44e-3)" "unprognostic (4.82e-2)" "unprognostic (2.50e-1)" "unprognostic (5.76e-3)" "unprognostic (1.50e-1)" MAIP1 "C2orf47, DKFZp666A212, FLJ22555" ENSG00000162972 "Matrix AAA peptidase interacting protein 1" Q8WWC4 2 199955317-200008540 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 101.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064013, HPA072231" Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 76: Non-specific - Metabolism" "Cluster 34: Non-specific - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 5 Mitochondria "HPA064013: , HPA072231: " "unprognostic (4.70e-2)" "unprognostic (9.63e-3)" "unprognostic (1.28e-2)" "unprognostic (3.38e-2)" "unprognostic (9.70e-3)" "unprognostic (2.70e-1)" "unprognostic (4.26e-2)" "unprognostic (2.90e-3)" "unprognostic (5.77e-2)" "potential prognostic favorable (3.27e-7)" "unprognostic (1.50e-2)" "unprognostic (2.62e-1)" "unprognostic (4.08e-2)" "unprognostic (1.63e-3)" "unprognostic (6.76e-2)" "unprognostic (6.30e-2)" "unprognostic (5.25e-2)" "unprognostic (7.25e-2)" "unprognostic (3.36e-1)" "unprognostic (5.73e-2)" "unprognostic (1.04e-1)" "unprognostic (1.30e-2)" "unprognostic (3.72e-2)" "unprognostic (1.85e-1)" "unprognostic (5.33e-3)" "unprognostic (3.19e-1)" "unprognostic (2.05e-1)" "unprognostic (7.96e-2)" "unprognostic (1.62e-1)" MAJIN C11orf85 ENSG00000168070 "Membrane anchored junction protein" Q3KP22 11 64937517-64972108 "Predicted intracellular proteins" Meiosis DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 21.0" "Cell type enriched" "Detected in many" 7 "Early primary spermatocytes: 253.0" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in some" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 3.4" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.3" "Lineage enriched" "Detected in single" 5 "B-cells: 1.3" "Cancer enriched" "Detected in some" 12 "Gallbladder cancer: 12.3" "Kidney - Proximal tubular cells, Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 57: Testis - Spermatogenesis" "Cluster 15: Non-specific - Transcription" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 3: Early primary spermatocytes - Early meiosis" 1 "potential prognostic favorable (4.27e-4)" "unprognostic (9.24e-2)" "unprognostic (1.45e-2)" "unprognostic (1.68e-1)" "unprognostic (1.00e-2)" "unprognostic (4.71e-2)" "unprognostic (2.13e-1)" "unprognostic (1.40e-1)" MAK "dJ417M14.2, RP62" ENSG00000111837 "Male germ cell associated kinase" P20794 6 10762723-10838553 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "retina: 110.1" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 1004.0;Epicardial cells: 484.4;Neutrophils: 258.1;Rod photoreceptor cells: 1372.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "neutrophil: 6.3" "Lineage enriched" "Detected in single" 9 "granulocytes: 6.3" "Low cancer specificity" "Detected in single" "Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Spleen - Neutrophils_2, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA077174 Approved "Nucleoplasm,Nucleoli,Plasma membrane,Basal body,Cytosol,Connecting piece,Principal piece,End piece" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 42: Retina - Visual perception" "Cluster 17: Choroid plexus - Cilium" "Cluster 1: Neuronal - Visual perception" "Cluster 79: Photoreceptor cells - Phototransduction" 7 "Nucleoplasm, Basal body, Cytosol, Connecting piece" "Nucleoli, Plasma membrane, Principal piece, End piece" "HPA077174: " "unprognostic (1.27e-1)" "unprognostic (2.08e-1)" "unprognostic (9.09e-3)" "unprognostic (9.49e-2)" "unprognostic (5.35e-2)" MAK16 "MAK16L, RBM13" ENSG00000198042 "MAK16 homolog" Q9BXY0 8 33485182-33501262 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 53.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044417, HPA050574" Uncertain Approved Nucleoli,Vesicles NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 61: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 40: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 60 "Nucleoli, Vesicles" "HPA044417: , HPA050574: " "unprognostic (1.43e-1)" "unprognostic (1.30e-1)" "unprognostic (2.69e-2)" "unprognostic (7.89e-2)" "unprognostic (4.96e-3)" "unprognostic (8.72e-2)" "unprognostic (1.15e-1)" "unprognostic (2.96e-1)" "unprognostic (3.70e-1)" "potential prognostic unfavorable (3.57e-4)" "unprognostic (1.31e-3)" "unprognostic (5.21e-2)" "unprognostic (2.94e-3)" "potential prognostic unfavorable (4.46e-4)" "unprognostic (6.77e-2)" "unprognostic (2.15e-1)" "unprognostic (1.20e-1)" "unprognostic (3.00e-2)" "unprognostic (2.23e-3)" "unprognostic (1.07e-1)" "unprognostic (5.20e-2)" "unprognostic (1.56e-1)" "unprognostic (4.03e-1)" "unprognostic (8.74e-2)" "unprognostic (4.12e-2)" "unprognostic (1.13e-3)" "unprognostic (2.60e-1)" "unprognostic (1.10e-1)" "unprognostic (3.54e-1)" "unprognostic (2.95e-1)" "unprognostic (3.22e-1)" MAL "MVP17, VIP17" ENSG00000172005 "Mal, T cell differentiation protein" P21145 2 95025677-95053992 "Predicted membrane proteins, Transporters" Leukodystrophy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 687.1;esophagus: 2851.1;vagina: 835.9" "Cell type enriched" "Detected in many" 33 "Esophageal apical cells: 40845.9" "Group enriched" "Detected in many" 5 "committed oligodendrocyte precursor: 96.2;oligodendrocyte: 286.7" "Group enriched" "Detected in many" 4 "Kidney Chromophobe (TCGA): 644.5;Kidney Renal Papillary Cell Carcinoma (TCGA): 423.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "memory CD4 T-cell: 218.3;naive CD4 T-cell: 294.2;naive CD8 T-cell: 138.5;T-reg: 234.3" "Lineage enriched" "Detected in many" 38 "T-cells: 294.2" "Cancer enhanced" "Detected in many" "Leukemia: 35.0;ovarian cancer: 68.6;Uterine cancer: 46.9" "Adipose subcutaneous - Smooth muscle cells, Colon - Enteric glia cells, Lung - Fibroblasts_1, Minor Salivary Gland - Minor salivary gland basal cells, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065691 Approved "Golgi apparatus,Centrosome,Basal body" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 11: White matter - Signal transduction" "Cluster 15: Kidney cancer - Membrane components" "Cluster 84: Apical squamous epithelium - Cornification" 68 "Golgi apparatus" "Centrosome, Basal body" "HPA065691: " "unprognostic (5.06e-2)" "potential prognostic favorable (5.92e-4)" "unprognostic (3.73e-3)" "unprognostic (3.01e-3)" "unprognostic (2.37e-2)" "unprognostic (3.78e-1)" "unprognostic (2.50e-2)" "unprognostic (3.17e-2)" "unprognostic (7.02e-2)" "unprognostic (1.46e-2)" "unprognostic (6.50e-2)" "unprognostic (4.36e-3)" "potential prognostic favorable (9.54e-4)" "unprognostic (1.86e-2)" "unprognostic (1.92e-2)" "unprognostic (1.43e-1)" "unprognostic (1.94e-1)" "unprognostic (7.50e-2)" "unprognostic (6.90e-2)" "unprognostic (6.08e-2)" "unprognostic (6.32e-2)" "unprognostic (2.31e-1)" "unprognostic (2.91e-1)" "unprognostic (2.98e-2)" "unprognostic (6.92e-2)" "unprognostic (1.82e-2)" MAL2 ENSG00000147676 "Mal, T cell differentiation protein 2" Q969L2 8 119165034-119245673 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 238.5" "Cell type enhanced" "Detected in many" "Colonocytes: 544.5;Esophageal apical cells: 2980.8;Esophageal suprabasal cells: 1251.6;Foveolar cells: 564.0;Gastric progenitor cells: 570.3;Ocular epithelial cells: 894.1;Suprabasal keratinocytes: 823.9" "Cell type enhanced" "Detected in all" "mammillary body: 169.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Pituitary gland - Lactotropes, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043831 Uncertain NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 42 "HPA043831: " "potential prognostic favorable (1.00e-5)" "potential prognostic unfavorable (4.68e-5)" "unprognostic (6.61e-2)" "unprognostic (1.20e-1)" "unprognostic (3.96e-1)" "potential prognostic unfavorable (2.25e-5)" "unprognostic (9.46e-2)" "unprognostic (3.49e-1)" "unprognostic (2.61e-2)" "unprognostic (3.71e-3)" "unprognostic (5.65e-2)" "unprognostic (5.77e-2)" "unprognostic (2.09e-1)" "unprognostic (6.08e-3)" "unprognostic (2.85e-3)" "unprognostic (6.63e-2)" "unprognostic (7.83e-3)" "unprognostic (1.07e-1)" "unprognostic (3.38e-1)" "unprognostic (4.01e-2)" "unprognostic (1.26e-1)" "potential prognostic unfavorable (9.32e-5)" "unprognostic (1.80e-2)" "unprognostic (2.37e-2)" "unprognostic (1.33e-1)" "unprognostic (1.54e-1)" "unprognostic (3.69e-2)" "unprognostic (8.89e-3)" "unprognostic (2.10e-2)" "unprognostic (2.10e-2)" "unprognostic (1.22e-1)" MALL BENE ENSG00000144063 "Mal, T cell differentiation protein like" Q13021 2 110083870-110116022 "Essential proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 482.8;intestine: 221.6;vagina: 189.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 21.0;Colonocytes: 20.1;Enterocytes: 53.9;Esophageal apical cells: 71.1;Esophageal suprabasal cells: 23.1;Ocular epithelial cells: 44.6;Prostatic club cells: 22.8;Prostatic hillock cells: 19.7;Transitional alveolar cells: 19.5;Urothelial cells: 50.3" "Cell type enriched" "Detected in single" 18 "endothelial cell: 4.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 8.2;neutrophil: 2.4" "Lineage enriched" "Detected in many" 7 "granulocytes: 8.2" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adrenal gland - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Alveolar cells type 2, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA051410 Uncertain NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 51 "HPA051410: " "unprognostic (1.63e-2)" "unprognostic (3.72e-1)" "unprognostic (1.45e-2)" "unprognostic (6.48e-3)" "unprognostic (1.62e-1)" "unprognostic (1.65e-1)" "unprognostic (9.26e-3)" "unprognostic (1.17e-1)" "unprognostic (1.20e-1)" "unprognostic (2.06e-3)" "unprognostic (1.24e-1)" "unprognostic (3.11e-1)" "unprognostic (9.63e-2)" "unprognostic (5.89e-2)" "unprognostic (2.03e-2)" "unprognostic (1.02e-1)" "unprognostic (9.14e-2)" "unprognostic (4.01e-2)" "unprognostic (4.60e-2)" "unprognostic (1.13e-1)" "potential prognostic unfavorable (1.09e-4)" "unprognostic (8.38e-2)" "unprognostic (2.62e-1)" "unprognostic (1.36e-1)" "unprognostic (1.06e-1)" "unprognostic (1.48e-1)" "unprognostic (6.79e-2)" "unprognostic (1.29e-1)" "unprognostic (2.28e-1)" "unprognostic (8.81e-3)" MALRD1 "bA265G8.2, C10orf112, Diet1" ENSG00000204740 "MAM and LDL receptor class A domain containing 1" Q5VYJ5 10 19048801-19790401 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "intestine: 29.3" "Cell type enhanced" "Detected in many" "Enteric stem cells: 349.9;Enteric transient amplifying cells: 296.6;Enterocytes: 927.4;Goblet cells: 221.3;Paneth cells: 924.3;Sertoli cells: 181.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Breast Invasive Carcinoma (TCGA): 3.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 1.2;Myeloma: 2.0" "Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA035732, HPA038106, HPA046848" Uncertain Enhanced "Golgi apparatus" NA NA 4700 "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 46: Brainstem - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 1: Enterocytes - Absorption and Digestion" "Golgi apparatus" "HPA035732: , HPA038106: , HPA046848: " "potential prognostic favorable (2.91e-4)" "potential prognostic favorable (7.66e-4)" "unprognostic (1.87e-1)" "unprognostic (8.00e-2)" "unprognostic (5.54e-2)" "unprognostic (3.19e-1)" "unprognostic (1.21e-1)" "unprognostic (1.71e-2)" MALSU1 "C7orf30, mtRsfA" ENSG00000156928 "Mitochondrial assembly of ribosomal large subunit 1" Q96EH3 7 23298739-23311729 "Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 235.2;Oocytes: 294.7;Retinal pigment epithelial cells: 221.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020487, HPA052210" Approved Enhanced Mitochondria NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 67: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 67 Mitochondria "HPA020487: , HPA052210: " "unprognostic (1.00e-1)" "unprognostic (1.19e-2)" "potential prognostic favorable (1.77e-4)" "unprognostic (1.22e-2)" "unprognostic (2.02e-1)" "unprognostic (8.34e-2)" "unprognostic (2.57e-2)" "unprognostic (4.39e-3)" "unprognostic (1.29e-1)" "validated prognostic unfavorable (2.55e-11)" "validated prognostic unfavorable (9.62e-5)" "potential prognostic unfavorable (2.67e-11)" "potential prognostic unfavorable (4.38e-4)" "potential prognostic unfavorable (4.88e-5)" "unprognostic (3.52e-2)" "unprognostic (7.36e-3)" "unprognostic (2.82e-2)" "unprognostic (1.55e-2)" "unprognostic (5.68e-2)" "unprognostic (1.35e-2)" "unprognostic (1.03e-1)" "unprognostic (2.99e-1)" "unprognostic (1.42e-1)" "unprognostic (4.54e-2)" "unprognostic (5.06e-2)" "unprognostic (2.03e-1)" "unprognostic (2.71e-1)" "unprognostic (1.10e-3)" "unprognostic (9.84e-2)" MALT1 "MLT, PCASP1" ENSG00000172175 "MALT1 paracaspase" Q9UDY8 18 58671465-58754477 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Immunity, Ubl conjugation pathway" "Hydrolase, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 19.0" "Cell type enhanced" "Detected in many" "cDC: 328.8;Innate lymphoid cells: 328.7;monocytes: 322.9;Myonuclei: 283.0;pDCs: 468.6;Prostatic glandular cells: 331.7;Thymocytes: 419.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Spleen - B-cells (Spleen), Testis - Spermatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004494, HPA048432" Enhanced Approved "Nucleoli fibrillar center,Cytosol" No No "Cluster 14: Non-specific - Unknown function" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 15: Non-specific - Transcription" "Cluster 55: Lymphoma - Immune response" "Cluster 82: Dendritic cells - Antigen presentation" 29 "Nucleoli fibrillar center" Cytosol "CAB004494: , HPA048432: " "unprognostic (1.07e-1)" "unprognostic (9.97e-2)" "unprognostic (2.70e-1)" "unprognostic (1.21e-1)" "unprognostic (1.81e-1)" "unprognostic (1.92e-1)" "unprognostic (1.10e-2)" "unprognostic (1.78e-1)" "unprognostic (2.93e-2)" "unprognostic (4.71e-2)" "unprognostic (2.43e-2)" "unprognostic (1.00e-2)" "unprognostic (4.95e-2)" "unprognostic (8.43e-2)" "unprognostic (2.11e-1)" "unprognostic (4.64e-2)" "unprognostic (1.47e-1)" "unprognostic (3.99e-2)" "unprognostic (2.49e-1)" "unprognostic (9.96e-2)" "unprognostic (8.96e-2)" "unprognostic (2.96e-1)" "unprognostic (1.58e-2)" "unprognostic (1.80e-1)" "unprognostic (1.83e-1)" "unprognostic (1.19e-2)" "unprognostic (3.22e-2)" "unprognostic (1.32e-1)" "unprognostic (2.86e-1)" "unprognostic (2.06e-1)" "unprognostic (5.37e-2)" MAMDC2 MGC21981 ENSG00000165072 "MAM domain containing 2" Q7Z304 9 70043848-70226972 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 72.0" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 94.1;Epicardial cells: 116.0;Fibro-adipogenic progenitors: 102.2;Fibroblasts: 132.1;Leydig cells: 154.1;Loop of henle epithelial cells: 73.7;Macrophages: 116.6;Papillary tip epithelial cells: 91.2;Peritubular myoid cells: 129.7;Renal collecting duct principal cells: 86.9;Smooth muscle cells: 142.1" "Cell type enhanced" "Detected in all" "mammillary body: 335.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 19.2" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Fibroblasts, Breast - Fibroblasts, Kidney - Fibroblasts, Pituitary gland - Fibroblasts, Skin - Fibroblasts_2, Spleen - Fibroblasts_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021814, HPA022249" Uncertain Approved "Nuclear speckles,Plasma membrane" "Secreted in other tissues" "No annotated function" NA NA 4000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 1 "Nuclear speckles, Plasma membrane" "HPA021814: , HPA022249: " "unprognostic (3.90e-1)" "unprognostic (2.40e-1)" "unprognostic (2.85e-1)" "unprognostic (5.34e-2)" "unprognostic (9.91e-2)" "unprognostic (2.91e-2)" "unprognostic (6.15e-2)" "unprognostic (7.32e-2)" "unprognostic (4.41e-2)" "unprognostic (1.06e-1)" "unprognostic (1.22e-1)" "unprognostic (3.20e-1)" "unprognostic (5.42e-3)" "unprognostic (4.45e-2)" "unprognostic (6.66e-3)" "unprognostic (3.45e-2)" "unprognostic (1.40e-2)" "unprognostic (7.74e-2)" "unprognostic (2.53e-1)" "unprognostic (9.27e-2)" "unprognostic (3.53e-1)" "unprognostic (3.21e-1)" "unprognostic (7.25e-2)" "unprognostic (8.68e-3)" "unprognostic (1.47e-1)" "unprognostic (3.45e-3)" MAMDC4 "AEGP, DKFZp434M1411, EDTB" ENSG00000177943 "MAM domain containing 4" Q6UXC1 9 136850943-136860799 "Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.6;liver: 31.0" "Cell type enhanced" "Detected in many" "Colonocytes: 24.8;Enterocytes: 20.6;Goblet cells: 25.3;Hepatocytes: 30.1;Tuft cells: 23.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebellum: 1.2" "Low region specificity" "Detected in all" "CAB026377, HPA059977" Approved Nucleoplasm,Cytosol NA Yes "Cluster 64: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 34: Testis cancer - Unknown function" "Cluster 65: Non-specific - Cell growth & division" Nucleoplasm Cytosol "CAB026377: , HPA059977: " "unprognostic (2.46e-2)" "unprognostic (7.21e-2)" "unprognostic (1.46e-1)" "unprognostic (1.48e-1)" "unprognostic (2.94e-1)" "unprognostic (1.25e-1)" "unprognostic (9.60e-2)" "unprognostic (1.32e-2)" "unprognostic (1.57e-3)" "unprognostic (6.15e-2)" "unprognostic (8.75e-3)" "unprognostic (1.99e-2)" "unprognostic (8.66e-3)" "unprognostic (7.06e-2)" "unprognostic (2.43e-2)" "unprognostic (1.62e-1)" "unprognostic (1.19e-3)" "potential prognostic favorable (1.78e-5)" "unprognostic (1.95e-1)" "unprognostic (9.33e-3)" "unprognostic (1.05e-1)" "unprognostic (7.41e-3)" "unprognostic (6.76e-3)" "unprognostic (5.25e-1)" "unprognostic (1.17e-1)" "unprognostic (3.10e-1)" MAML1 "KIAA0200, Mam-1" ENSG00000161021 "Mastermind like transcriptional coactivator 1" Q92585 5 179732822-179777283 "Predicted intracellular proteins" "Notch signaling pathway, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 21.2;Bergmann glia: 22.7;Brain excitatory neurons: 31.9;Brain inhibitory neurons: 28.7;Choroid plexus epithelial cells: 39.4;Distal convoluted tubule cells: 38.1;Loop of henle epithelial cells: 30.8;Microglia: 38.6;Oligodendrocyte progenitor cells: 25.5;Oligodendrocytes: 24.9;Other brain neurons: 20.2;Papillary tip epithelial cells: 20.8;Podocytes: 27.9;Proximal tubule cells: 37.0;Renal collecting duct intercalated cells: 31.5;Renal collecting duct principal cells: 23.5;Renal connecting tubule cells: 31.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Pancreas - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037687, HPA057531" Approved Supported Nucleoplasm NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 102: Non-specific - Mixed function" 10 Nucleoplasm "HPA037687: , HPA057531: " "unprognostic (3.92e-3)" "unprognostic (4.83e-1)" "unprognostic (8.19e-2)" "unprognostic (3.38e-2)" "unprognostic (2.94e-1)" "unprognostic (1.93e-2)" "unprognostic (9.24e-2)" "unprognostic (7.50e-2)" "unprognostic (1.04e-1)" "unprognostic (2.05e-1)" "unprognostic (4.47e-2)" "unprognostic (4.34e-1)" "unprognostic (6.85e-2)" "unprognostic (8.60e-2)" "unprognostic (1.05e-1)" "unprognostic (2.80e-1)" "unprognostic (4.35e-1)" "unprognostic (3.21e-1)" "unprognostic (2.59e-1)" "unprognostic (2.15e-2)" "unprognostic (1.32e-3)" "unprognostic (9.37e-2)" "unprognostic (1.61e-1)" "unprognostic (1.58e-1)" "unprognostic (5.68e-2)" "unprognostic (1.59e-2)" "unprognostic (3.49e-1)" "unprognostic (1.06e-1)" "unprognostic (7.16e-3)" "unprognostic (1.43e-1)" MAML2 "KIAA1819, MAM3" ENSG00000184384 "Mastermind like transcriptional coactivator 2" Q8IZL2 11 95976598-96343195 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Notch signaling pathway, Transcription, Transcription regulation" Activator "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 2700.3" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 3870.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Breast - Breast myoepithelial cells, Lung - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035223 Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" No No "Cluster 43: Non-specific - Transcription & Translation" "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" "Nuclear bodies" "Nucleoplasm, Cytosol" "HPA035223: " "unprognostic (7.10e-2)" "unprognostic (4.51e-2)" "unprognostic (4.29e-1)" "unprognostic (4.13e-3)" "unprognostic (1.14e-1)" "unprognostic (1.72e-2)" "unprognostic (9.12e-3)" "unprognostic (1.07e-2)" "unprognostic (1.63e-2)" "unprognostic (9.46e-2)" "validated prognostic favorable (3.01e-9)" "validated prognostic favorable (5.11e-5)" "unprognostic (8.27e-2)" "unprognostic (6.84e-2)" "unprognostic (4.87e-2)" "unprognostic (7.53e-3)" "unprognostic (7.88e-2)" "unprognostic (1.45e-1)" "unprognostic (5.27e-2)" "unprognostic (3.15e-2)" "unprognostic (3.04e-3)" "unprognostic (1.92e-1)" "unprognostic (1.28e-1)" "unprognostic (7.66e-2)" "unprognostic (3.54e-2)" "unprognostic (3.34e-2)" "unprognostic (3.09e-2)" "unprognostic (1.04e-1)" "unprognostic (1.35e-1)" "unprognostic (3.92e-1)" MAML3 "CAGH3, GDN, KIAA1816, MAM2, TNRC3" ENSG00000196782 "Mastermind like transcriptional coactivator 3" Q96JK9 4 139716753-140154184 "Predicted intracellular proteins" "Notch signaling pathway, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Corticotrophs: 1329.4;Lactotrophs: 1633.3;Microglia: 1515.1;Neutrophils: 2834.2" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 1930.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 5.7" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Neuroblastoma: 14.9" "Pituitary gland - Lactotropes, Skin - Keratinocyte (other)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA037717 Approved Supported "Nuclear speckles" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 58: Skin - Keratinization" "Cluster 25: Non-specific - Transcription" "Cluster 65: Non-specific - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" 4 "Nuclear speckles" "HPA037717: " "unprognostic (3.22e-2)" "unprognostic (1.83e-1)" "unprognostic (2.49e-1)" "unprognostic (1.06e-1)" "unprognostic (1.04e-1)" "unprognostic (5.16e-3)" "unprognostic (8.42e-2)" "unprognostic (1.62e-1)" "unprognostic (4.29e-1)" "unprognostic (7.96e-2)" "validated prognostic favorable (3.90e-8)" "validated prognostic favorable (8.06e-4)" "unprognostic (2.47e-2)" "unprognostic (1.07e-2)" "potential prognostic favorable (3.11e-4)" "unprognostic (9.10e-2)" "unprognostic (1.46e-1)" "unprognostic (1.04e-1)" "unprognostic (1.45e-1)" "unprognostic (5.86e-2)" "unprognostic (4.34e-3)" "unprognostic (3.27e-2)" "unprognostic (3.57e-1)" "unprognostic (1.80e-1)" "unprognostic (1.37e-1)" "unprognostic (9.81e-3)" "unprognostic (6.32e-2)" "unprognostic (1.16e-1)" "unprognostic (2.12e-1)" "unprognostic (1.41e-1)" "unprognostic (3.69e-3)" MAMLD1 "CG1, CXorf6, F18" ENSG00000013619 "Mastermind like domain containing 1" Q13495 X 150361422-150514178 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 109.7;Gonadotrophs: 109.7;Leydig cells: 193.9;monocytes: 116.8;Oligodendrocyte progenitor cells: 143.1;Pancreatic islet cells: 103.1;Peritubular myoid cells: 105.9;Sertoli cells: 370.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Pituitary gland - Corticotropes, Prostate - Smooth muscle cells, Spleen - Fibroblasts_2, Testis - Sertoli cells, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003923 Uncertain Supported "Nucleoplasm,Nuclear bodies,Golgi apparatus,Centrosome" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 14: Neurons - Synaptic function" "Cluster 54: Non-specific - Transcription" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" Nucleoplasm "Nuclear bodies, Golgi apparatus, Centrosome" "HPA003923: " "unprognostic (2.01e-1)" "unprognostic (1.26e-1)" "unprognostic (1.63e-2)" "unprognostic (1.76e-2)" "potential prognostic unfavorable (9.92e-4)" "unprognostic (1.95e-2)" "unprognostic (4.50e-2)" "unprognostic (2.19e-1)" "unprognostic (3.99e-1)" "potential prognostic favorable (3.18e-4)" "unprognostic (7.10e-2)" "unprognostic (3.05e-1)" "unprognostic (2.59e-1)" "unprognostic (2.36e-3)" "unprognostic (3.32e-1)" "unprognostic (3.19e-3)" "unprognostic (7.84e-2)" "unprognostic (3.14e-2)" "unprognostic (2.27e-1)" "unprognostic (2.91e-2)" "unprognostic (2.08e-1)" "unprognostic (6.80e-3)" "unprognostic (9.24e-2)" "unprognostic (1.12e-1)" "unprognostic (5.81e-2)" "unprognostic (2.71e-2)" "unprognostic (2.30e-1)" "unprognostic (1.71e-2)" "unprognostic (1.07e-1)" MAMSTR "FLJ36070, MASTR" ENSG00000176909 "MEF2 activating motif and SAP domain containing transcriptional regulator" Q6ZN01 19 48712725-48719725 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adrenal gland: 31.4;skeletal muscle: 83.3;tongue: 21.1" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 109.1;Granulosa cells: 57.6;Myonuclei: 271.4" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Ovary Serous Cystadenocarcinoma (TCGA): 13.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Adrenocortical cancer: 15.6;Rhabdoid: 29.5;Sarcoma: 21.8" "Adipose visceral - Mesothelial cells, Pituitary gland - Gonadotropes, Prostate - Fibroblasts, Testis - Sertoli cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA049765 Approved "Nuclear speckles" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 15: Non-specific - Transcription" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" "Nuclear speckles" "HPA049765: " "unprognostic (9.72e-2)" "unprognostic (2.79e-1)" "unprognostic (9.68e-2)" "unprognostic (4.49e-2)" "unprognostic (1.54e-1)" "unprognostic (1.03e-1)" "unprognostic (1.02e-2)" "unprognostic (1.18e-1)" "unprognostic (8.32e-3)" "unprognostic (2.51e-2)" "unprognostic (4.21e-1)" "unprognostic (1.66e-1)" "potential prognostic unfavorable (5.35e-5)" "unprognostic (1.31e-2)" "unprognostic (2.43e-1)" "unprognostic (1.11e-2)" "unprognostic (5.42e-2)" "unprognostic (7.51e-2)" "unprognostic (1.90e-1)" "unprognostic (4.60e-2)" "unprognostic (8.74e-3)" "unprognostic (7.56e-2)" "unprognostic (2.60e-2)" "unprognostic (1.55e-1)" "unprognostic (6.19e-2)" "unprognostic (1.65e-1)" "unprognostic (3.20e-3)" "unprognostic (1.39e-1)" MAN1A1 ENSG00000111885 "Mannosidase alpha class 1A member 1" P33908 6 119177205-119349761 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 144.6" "Cell type enhanced" "Detected in many" "Hematopoietic stem cells: 809.4;Macrophages: 845.5;Plasma cells: 754.7;Thymocytes: 637.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Myeloma: 117.4" "Liver - Hepatocytes, Minor Salivary Gland - Macrophages, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037058, HPA053198, HPA063561" Uncertain Supported "Golgi apparatus" NA NA 330000000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 33: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 16 "Golgi apparatus" "CAB037058: , HPA053198: , HPA063561: " "unprognostic (9.84e-3)" "unprognostic (1.22e-1)" "unprognostic (1.21e-1)" "unprognostic (6.10e-2)" "unprognostic (2.90e-1)" "unprognostic (2.52e-2)" "unprognostic (1.25e-2)" "unprognostic (9.76e-3)" "unprognostic (2.52e-1)" "unprognostic (6.50e-2)" "potential prognostic favorable (9.44e-6)" "unprognostic (1.07e-1)" "unprognostic (1.07e-1)" "unprognostic (6.92e-3)" "unprognostic (3.38e-3)" "unprognostic (1.41e-2)" "unprognostic (4.37e-2)" "unprognostic (1.35e-1)" "unprognostic (4.76e-3)" "unprognostic (7.48e-2)" "unprognostic (1.15e-3)" "unprognostic (4.49e-3)" "unprognostic (1.71e-1)" "unprognostic (3.37e-1)" "unprognostic (1.44e-1)" "unprognostic (2.16e-1)" "unprognostic (1.97e-1)" "unprognostic (1.25e-2)" "unprognostic (1.54e-1)" "unprognostic (3.00e-2)" "unprognostic (9.37e-2)" MAN1A2 MAN1B ENSG00000198162 "Mannosidase alpha class 1A member 2" O60476 1 117367449-117528872 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 675.7;Syncytiotrophoblasts: 912.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034559, HPA057364" Enhanced Enhanced "Golgi apparatus" NA NA 2500000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 16: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 5 "Golgi apparatus" "HPA034559: , HPA057364: " "unprognostic (1.24e-2)" "unprognostic (2.61e-1)" "unprognostic (4.03e-1)" "unprognostic (8.84e-2)" "unprognostic (1.37e-2)" "potential prognostic unfavorable (5.45e-4)" "unprognostic (1.04e-1)" "unprognostic (1.14e-2)" "unprognostic (1.60e-1)" "potential prognostic unfavorable (6.44e-6)" "potential prognostic favorable (2.41e-5)" "unprognostic (1.07e-3)" "unprognostic (6.61e-2)" "unprognostic (7.15e-2)" "unprognostic (3.21e-1)" "unprognostic (5.45e-2)" "unprognostic (2.76e-1)" "unprognostic (1.63e-1)" "unprognostic (8.52e-2)" "unprognostic (6.25e-2)" "unprognostic (1.24e-2)" "unprognostic (8.32e-2)" "unprognostic (1.17e-1)" "unprognostic (3.02e-1)" "unprognostic (7.04e-2)" "unprognostic (1.94e-2)" "unprognostic (6.76e-2)" "unprognostic (1.91e-1)" "unprognostic (1.43e-1)" "unprognostic (6.55e-2)" "unprognostic (5.79e-2)" MAN1B1 "ERMan1, ERManI, MANA-ER, MRT15" ENSG00000177239 "Mannosidase alpha class 1B member 1" Q9UKM7 9 137086857-137109189 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Glycosidase, Hydrolase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 102.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051516 Approved Uncertain Vesicles NA NA 470000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 58: Skin - Keratinization" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 20 Vesicles "HPA051516: " "unprognostic (1.92e-3)" "unprognostic (9.79e-3)" "unprognostic (2.75e-1)" "unprognostic (3.33e-2)" "unprognostic (2.07e-1)" "unprognostic (5.61e-2)" "unprognostic (6.83e-3)" "unprognostic (7.35e-2)" "unprognostic (1.66e-2)" "unprognostic (1.54e-1)" "unprognostic (3.54e-2)" "unprognostic (1.58e-2)" "unprognostic (1.42e-2)" "validated prognostic unfavorable (2.00e-5)" "validated prognostic unfavorable (4.24e-4)" "unprognostic (1.01e-1)" "unprognostic (8.20e-2)" "unprognostic (5.11e-2)" "unprognostic (2.80e-1)" "unprognostic (9.27e-2)" "unprognostic (6.05e-2)" "unprognostic (4.55e-2)" "unprognostic (3.56e-2)" "unprognostic (2.86e-1)" "unprognostic (5.66e-2)" "unprognostic (1.14e-1)" "unprognostic (4.69e-2)" "unprognostic (1.41e-1)" "unprognostic (2.88e-1)" "unprognostic (1.52e-1)" "unprognostic (8.31e-3)" MAN1C1 HMIC ENSG00000117643 "Mannosidase alpha class 1C member 1" Q9NR34 1 25616791-25786206 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 284.9;Cone photoreceptor cells: 356.1;Fibro-adipogenic progenitors: 180.1;Lactotrophs: 186.1;Renal collecting duct intercalated cells: 250.5;Somatotrophs: 200.8;Syncytiotrophoblasts: 283.8;Thyrotrophs: 252.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 4.8" "Lineage enriched" "Detected in many" 5 "T-cells: 4.8" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048352 Uncertain Uncertain Nucleoplasm,Vesicles NA NA 1300000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 9: T-cells - Adaptive immunity: Regulation" 2 "Nucleoplasm, Vesicles" "HPA048352: " "unprognostic (9.09e-2)" "unprognostic (1.51e-1)" "unprognostic (4.48e-3)" "unprognostic (5.87e-2)" "unprognostic (4.28e-2)" "unprognostic (1.00e-1)" "unprognostic (1.59e-1)" "unprognostic (1.23e-1)" "unprognostic (3.41e-2)" "unprognostic (3.90e-1)" "unprognostic (8.40e-2)" "unprognostic (2.75e-1)" "unprognostic (3.48e-2)" "unprognostic (4.57e-2)" "potential prognostic favorable (2.11e-5)" "unprognostic (3.37e-3)" "unprognostic (1.74e-1)" "unprognostic (7.00e-2)" "unprognostic (3.28e-1)" "unprognostic (2.67e-2)" "unprognostic (2.72e-1)" "unprognostic (1.85e-3)" "unprognostic (2.14e-1)" "unprognostic (1.66e-1)" "unprognostic (3.75e-2)" "unprognostic (4.80e-2)" "unprognostic (2.00e-1)" "unprognostic (5.56e-2)" "unprognostic (1.73e-1)" "unprognostic (1.12e-1)" "unprognostic (2.19e-1)" MAN2A1 "GOLIM7, MANA2" ENSG00000112893 "Mannosidase alpha class 2A member 1" Q16706 5 109689927-109869625 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 2075.1" "Cell type enriched" "Detected in all" 5 "oligodendrocyte: 3403.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022377, HPA026896" Enhanced Supported "Golgi apparatus" NA NA 85000000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 77: Intestine - Digestion" "Cluster 11: White matter - Signal transduction" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 80: Oligodendrocytes - Myelination" 10 "Golgi apparatus" "CAB022377: , HPA026896: " "unprognostic (4.85e-2)" "unprognostic (5.95e-2)" "unprognostic (1.13e-1)" "unprognostic (4.01e-2)" "unprognostic (1.32e-2)" "unprognostic (2.59e-2)" "unprognostic (2.22e-1)" "unprognostic (9.96e-2)" "unprognostic (9.48e-2)" "unprognostic (4.64e-3)" "potential prognostic favorable (3.64e-7)" "unprognostic (1.84e-2)" "unprognostic (1.08e-2)" "unprognostic (2.75e-1)" "unprognostic (6.40e-2)" "unprognostic (8.48e-3)" "unprognostic (1.38e-2)" "unprognostic (1.77e-1)" "unprognostic (4.48e-2)" "unprognostic (7.80e-2)" "potential prognostic unfavorable (5.38e-4)" "unprognostic (2.91e-2)" "unprognostic (1.18e-1)" "unprognostic (1.94e-1)" "unprognostic (5.11e-2)" "unprognostic (1.17e-2)" "unprognostic (4.83e-1)" "unprognostic (5.97e-3)" "unprognostic (3.24e-1)" "potential prognostic unfavorable (2.68e-4)" "unprognostic (1.51e-1)" MAN2A2 "HsT19662, MANA2X" ENSG00000196547 "Mannosidase alpha class 2A member 2" P49641 15 90902218-90922584 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythrocyte progenitors: 83.2;Neutrophils: 212.5;Oligodendrocytes: 106.5;Platelets: 128.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 8.8;neutrophil: 8.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077930 Approved "Cytoplasmic bodies" NA NA 14000000 "Cluster 20: Non-specific - DNA binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 47: Leukemia - Hemostasis" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 2 "Cytoplasmic bodies" "HPA077930: " "unprognostic (5.49e-3)" "unprognostic (1.76e-1)" "potential prognostic favorable (7.32e-4)" "unprognostic (1.40e-2)" "unprognostic (3.18e-2)" "unprognostic (6.10e-2)" "unprognostic (2.35e-1)" "unprognostic (9.38e-2)" "unprognostic (1.08e-1)" "unprognostic (6.63e-2)" "unprognostic (3.09e-1)" "unprognostic (2.16e-2)" "unprognostic (3.31e-1)" "unprognostic (2.59e-1)" "unprognostic (1.97e-1)" "unprognostic (2.21e-1)" "unprognostic (1.17e-1)" "unprognostic (2.72e-2)" "unprognostic (2.81e-3)" "unprognostic (2.68e-1)" "unprognostic (8.16e-3)" "unprognostic (6.62e-3)" "unprognostic (1.92e-1)" "unprognostic (2.88e-3)" "unprognostic (1.46e-1)" "unprognostic (3.53e-2)" "unprognostic (1.61e-1)" "unprognostic (1.98e-3)" "unprognostic (4.49e-1)" "unprognostic (1.46e-1)" "unprognostic (2.27e-2)" MAN2B1 "LAMAN, MANB" ENSG00000104774 "Mannosidase alpha class 2B member 1" O00754 19 12646511-12666742 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "cDC: 54.6;Macrophages: 47.9;Microglia: 71.6;monocytes: 47.1;Neutrophils: 70.2;pDCs: 102.9" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 89.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 201.7;intermediate monocyte: 178.7;myeloid DC: 159.0;non-classical monocyte: 139.1;plasmacytoid DC: 187.7" "Group enriched" "Detected in all" 5 "dendritic cells: 187.7;monocytes: 201.7" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Lung - Macrophages, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041530, HPA053404" Supported Approved Nucleoplasm,Vesicles "Intracellular and membrane" Enzyme NA NA 1800000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 15 "Nucleoplasm, Vesicles" "HPA041530: , HPA053404: " "unprognostic (6.49e-2)" "unprognostic (7.52e-2)" "potential prognostic favorable (9.55e-4)" "unprognostic (1.18e-1)" "unprognostic (2.36e-1)" "unprognostic (4.29e-1)" "unprognostic (4.89e-2)" "unprognostic (6.18e-3)" "unprognostic (1.22e-1)" "unprognostic (1.71e-1)" "unprognostic (3.82e-3)" "unprognostic (4.10e-2)" "unprognostic (3.10e-3)" "unprognostic (1.24e-1)" "unprognostic (1.72e-1)" "unprognostic (3.12e-2)" "unprognostic (4.22e-1)" "unprognostic (2.76e-1)" "unprognostic (1.41e-1)" "unprognostic (3.43e-1)" "unprognostic (4.18e-3)" "unprognostic (5.39e-2)" "unprognostic (1.12e-2)" "unprognostic (4.15e-1)" "unprognostic (1.34e-2)" "unprognostic (6.61e-2)" "unprognostic (1.37e-1)" "unprognostic (3.26e-1)" "unprognostic (3.98e-2)" "unprognostic (2.85e-1)" "unprognostic (2.09e-1)" MAN2B2 "EpMAN, KIAA0935" ENSG00000013288 "Mannosidase alpha class 2B member 2" Q9Y2E5 4 6575189-6623362 "Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "Secreted to blood" Enzyme NA NA 3600000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 74: Non-specific - Signal transduction" "Cluster 23: Choroid plexus - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 108: Fibroblasts - ECM organization" 10 "unprognostic (1.74e-2)" "unprognostic (2.31e-1)" "unprognostic (3.28e-1)" "unprognostic (4.24e-2)" "unprognostic (4.56e-2)" "unprognostic (8.33e-2)" "unprognostic (1.43e-1)" "unprognostic (8.76e-2)" "unprognostic (1.15e-1)" "unprognostic (9.81e-3)" "potential prognostic favorable (1.28e-4)" "unprognostic (1.67e-1)" "unprognostic (1.73e-1)" "unprognostic (2.18e-1)" "unprognostic (3.96e-1)" "unprognostic (1.31e-1)" "unprognostic (2.51e-1)" "unprognostic (1.01e-1)" "unprognostic (1.36e-1)" "unprognostic (7.04e-2)" "unprognostic (1.28e-1)" "unprognostic (7.06e-2)" "unprognostic (1.84e-1)" "unprognostic (2.41e-1)" "unprognostic (1.08e-1)" "unprognostic (1.61e-2)" "unprognostic (1.68e-1)" "unprognostic (3.98e-1)" "unprognostic (1.19e-1)" "unprognostic (4.98e-3)" "unprognostic (2.73e-2)" MAN2C1 "MANA, MANA1" ENSG00000140400 "Mannosidase alpha class 2C member 1" Q9NTJ4 15 75355207-75368612 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040627, HPA067407" Uncertain NA NA 5600 "Cluster 33: Non-specific - ATP binding" "Cluster 24: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 105: Non-specific - Mixed function" 4 "HPA040627: , HPA067407: " "unprognostic (8.48e-2)" "unprognostic (9.84e-2)" "unprognostic (6.42e-3)" "unprognostic (1.72e-1)" "unprognostic (3.62e-2)" "unprognostic (2.01e-1)" "unprognostic (5.17e-1)" "unprognostic (2.17e-2)" "unprognostic (2.79e-1)" "unprognostic (1.39e-1)" "unprognostic (7.92e-2)" "potential prognostic favorable (1.31e-4)" "unprognostic (5.83e-3)" "potential prognostic favorable (7.08e-4)" "unprognostic (3.95e-1)" "unprognostic (8.36e-2)" "unprognostic (1.79e-1)" "unprognostic (4.95e-2)" "unprognostic (1.34e-1)" "unprognostic (1.71e-2)" "unprognostic (1.79e-2)" "unprognostic (1.17e-1)" "potential prognostic unfavorable (1.07e-4)" "unprognostic (3.36e-1)" "unprognostic (4.46e-2)" "unprognostic (4.95e-2)" "unprognostic (4.45e-1)" "unprognostic (1.30e-1)" "unprognostic (5.34e-1)" "unprognostic (5.95e-2)" "unprognostic (1.65e-1)" MANBA ENSG00000109323 "Mannosidase beta" O00462 4 102630770-102760994 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "cDC: 298.1;Macrophages: 398.0;Mast cells: 282.6;Microglia: 413.5;monocytes: 536.5;Neutrophil progenitors: 569.7;Neutrophils: 711.9" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 545.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 16.6" "Group enriched" "Detected in many" 5 "dendritic cells: 5.3;granulocytes: 16.6;monocytes: 9.1" "Low cancer specificity" "Detected in many" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037698, HPA047826, HPA053478" Approved Enhanced Vesicles NA NA 13000000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 70: Non-specific - Protein processing" "Cluster 49: Hindbrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 19 Vesicles "HPA037698: , HPA047826: , HPA053478: " "unprognostic (1.23e-1)" "unprognostic (6.74e-3)" "unprognostic (2.60e-1)" "unprognostic (1.34e-2)" "unprognostic (2.03e-1)" "unprognostic (6.70e-2)" "unprognostic (4.85e-3)" "unprognostic (1.40e-2)" "unprognostic (1.93e-1)" "unprognostic (1.96e-1)" "unprognostic (4.04e-3)" "unprognostic (4.09e-2)" "unprognostic (9.81e-3)" "unprognostic (2.27e-1)" "unprognostic (5.79e-2)" "unprognostic (5.56e-2)" "unprognostic (3.38e-2)" "unprognostic (2.30e-1)" "unprognostic (3.77e-2)" "unprognostic (9.64e-2)" "unprognostic (2.69e-1)" "unprognostic (1.28e-2)" MANBAL dJ1141E15.2 ENSG00000101363 "Mannosidase beta like" Q9NQG1 20 37289649-37317260 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 137.6;Extravillous trophoblasts: 173.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052348 Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 74: Non-specific - Signal transduction" "Cluster 27: Non-specific - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 20 Mitochondria Nucleoplasm "HPA052348: " "unprognostic (7.99e-2)" "unprognostic (2.68e-2)" "unprognostic (7.28e-3)" "unprognostic (2.26e-1)" "unprognostic (6.24e-2)" "unprognostic (1.94e-1)" "unprognostic (1.22e-1)" "unprognostic (2.84e-1)" "unprognostic (1.16e-3)" "unprognostic (1.83e-1)" "unprognostic (1.70e-2)" "unprognostic (2.73e-1)" "unprognostic (5.24e-3)" "validated prognostic unfavorable (1.18e-5)" "validated prognostic unfavorable (1.02e-5)" "unprognostic (2.08e-3)" "unprognostic (2.44e-1)" "unprognostic (1.52e-1)" "unprognostic (1.68e-1)" "unprognostic (5.01e-2)" "unprognostic (8.10e-3)" "unprognostic (3.05e-1)" "unprognostic (1.45e-1)" "unprognostic (3.71e-1)" "unprognostic (1.95e-1)" "unprognostic (1.97e-1)" "unprognostic (2.70e-1)" "unprognostic (2.42e-1)" "unprognostic (7.60e-2)" "unprognostic (1.15e-1)" "unprognostic (1.78e-1)" MANEA "FLJ12838, mandaselin" ENSG00000172469 "Mannosidase endo-alpha" Q5SRI9 6 95577485-95609470 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 68.8;Plasma cells: 129.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Minor Salivary Gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011046, HPA011069" Enhanced Supported "Golgi apparatus" NA NA 55000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 67: Plasma cells - Plasma cell differentiation" 2 "Golgi apparatus" "HPA011046: , HPA011069: " "unprognostic (2.36e-2)" "unprognostic (4.81e-2)" "unprognostic (4.46e-3)" "unprognostic (7.11e-2)" "unprognostic (4.48e-2)" "unprognostic (1.35e-1)" "unprognostic (6.77e-2)" "unprognostic (5.91e-3)" "unprognostic (1.89e-1)" "unprognostic (7.02e-3)" "potential prognostic favorable (9.81e-6)" "unprognostic (2.74e-2)" "unprognostic (2.20e-1)" "unprognostic (1.08e-2)" "unprognostic (5.19e-2)" "unprognostic (2.70e-1)" "unprognostic (4.93e-2)" "unprognostic (2.03e-1)" "unprognostic (1.40e-1)" "unprognostic (1.18e-1)" "unprognostic (6.90e-3)" "unprognostic (1.03e-1)" "unprognostic (5.21e-2)" "unprognostic (9.63e-2)" "unprognostic (4.85e-2)" "unprognostic (2.51e-2)" "unprognostic (1.07e-1)" "unprognostic (2.04e-1)" "unprognostic (2.79e-1)" "unprognostic (9.03e-2)" "unprognostic (1.51e-1)" MANEAL FLJ31434 ENSG00000185090 "Mannosidase endo-alpha like" Q5VSG8 1 37793847-37801137 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.5" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 15.3;Cone photoreceptor cells: 16.6;Corticotrophs: 20.9;Gonadotrophs: 16.5;Neuroendocrine cells: 16.6;Other brain neurons: 21.4;Pancreatic islet cells: 19.2;Retinal amacrine cells: 22.2;Retinal bipolar cells: 13.7;Retinal ganglion cells: 19.3;Retinal horizontal cells: 18.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063423 Approved "Golgi apparatus" "Intracellular and membrane" Enzyme NA NA 17000 "Cluster 36: Brain & Liver - Signaling" "Cluster 1: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 2 "Golgi apparatus" "HPA063423: " "unprognostic (2.72e-3)" "unprognostic (4.61e-2)" "unprognostic (1.17e-1)" "unprognostic (4.28e-1)" "unprognostic (3.30e-1)" "unprognostic (8.26e-2)" "unprognostic (9.63e-2)" "potential prognostic favorable (5.72e-5)" "potential prognostic favorable (4.71e-4)" "unprognostic (4.61e-3)" "unprognostic (8.79e-3)" "unprognostic (7.31e-3)" "potential prognostic unfavorable (4.47e-5)" "validated prognostic unfavorable (8.96e-4)" "validated prognostic unfavorable (3.46e-5)" "unprognostic (7.02e-2)" "unprognostic (6.72e-2)" "unprognostic (1.41e-1)" "unprognostic (4.20e-1)" "unprognostic (1.06e-1)" "unprognostic (1.01e-1)" "unprognostic (2.52e-2)" "unprognostic (1.13e-2)" "unprognostic (1.69e-1)" "unprognostic (2.40e-1)" "unprognostic (5.69e-2)" "unprognostic (1.38e-3)" "unprognostic (2.22e-3)" "unprognostic (4.23e-1)" "unprognostic (7.35e-2)" "unprognostic (3.56e-1)" MANF "ARMET, ARP" ENSG00000145050 "Mesencephalic astrocyte derived neurotrophic factor" P55145 3 51385291-51389397 "Plasma proteins, Predicted secreted proteins" "Stress response, Unfolded protein response" "Growth factor" "Deafness, Diabetes mellitus, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal basal cells: 386.9;Epididymal principal cells: 834.3;Esophageal apical cells: 403.3;Extravillous trophoblasts: 493.8;Plasma cells: 614.3;Syncytiotrophoblasts: 593.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 109.9" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011175 Approved Supported "Endoplasmic reticulum" "Secreted to blood" "Growth factor" NA NA 6400000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 70: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 8: Non-specific - Secretory pathway" 18 "Endoplasmic reticulum" "HPA011175: " "unprognostic (9.08e-2)" "unprognostic (2.21e-1)" "unprognostic (2.40e-1)" "unprognostic (9.94e-3)" "unprognostic (4.93e-3)" "unprognostic (1.30e-1)" "potential prognostic unfavorable (7.04e-4)" "unprognostic (2.71e-2)" "unprognostic (1.95e-3)" "unprognostic (5.85e-3)" "unprognostic (1.65e-2)" "unprognostic (1.28e-2)" "unprognostic (1.13e-1)" "potential prognostic unfavorable (6.11e-4)" "unprognostic (6.02e-3)" "unprognostic (2.14e-3)" "unprognostic (3.04e-2)" "unprognostic (6.52e-2)" "unprognostic (1.39e-1)" "unprognostic (7.62e-3)" "unprognostic (3.65e-1)" "unprognostic (1.24e-1)" "unprognostic (3.62e-2)" "unprognostic (1.74e-1)" "unprognostic (1.88e-1)" "unprognostic (5.01e-2)" "unprognostic (2.01e-1)" "unprognostic (1.74e-1)" "unprognostic (2.18e-1)" "unprognostic (1.27e-1)" "unprognostic (3.14e-1)" MANSC1 "FLJ10298, LOH12CR3" ENSG00000111261 "MANSC domain containing 1" Q9H8J5 12 12326056-12350242 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 65.5" "Cell type enhanced" "Detected in some" "Astrocytes: 10.9;Bergmann glia: 10.3;Brain excitatory neurons: 18.4;Brain inhibitory neurons: 17.8;Choroid plexus epithelial cells: 12.7;Ependymal cells: 23.6;Loop of henle epithelial cells: 7.9;Oligodendrocyte progenitor cells: 9.1;Oligodendrocytes: 13.5;Other brain neurons: 14.2;Papillary tip epithelial cells: 16.6;Podocytes: 14.7;Renal collecting duct principal cells: 18.4;Retinal pigment epithelial cells: 8.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 15 "neutrophil: 98.6" "Lineage enriched" "Detected in many" 39 "granulocytes: 98.6" "Cancer enriched" "Detected in many" 6 "Bile duct cancer: 134.6" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Thyrotropes, Skeletal muscle - Endothelial cells, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "HPA007955, HPA007956" Approved Approved "Golgi apparatus,Vesicles" NA NA 1600000 "Cluster 4: Neutrophils - Degranulation" "Cluster 60: Stomach - Digestion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 98: Neurons - Neurotransmission & signaling" 5 Vesicles "Golgi apparatus" "HPA007955: , HPA007956: " "potential prognostic favorable (3.61e-4)" "unprognostic (2.28e-3)" "unprognostic (1.75e-1)" "unprognostic (3.42e-2)" "unprognostic (4.81e-2)" "unprognostic (1.11e-1)" "unprognostic (3.86e-1)" "unprognostic (4.05e-3)" "unprognostic (1.30e-1)" "unprognostic (3.25e-2)" "potential prognostic favorable (2.17e-8)" "unprognostic (1.27e-3)" "unprognostic (2.84e-1)" "unprognostic (4.29e-2)" "unprognostic (2.48e-3)" "unprognostic (4.65e-3)" "unprognostic (3.44e-2)" "unprognostic (3.97e-1)" "unprognostic (1.52e-1)" "unprognostic (2.81e-1)" "unprognostic (2.81e-1)" "unprognostic (1.97e-2)" "unprognostic (3.76e-2)" "unprognostic (2.38e-1)" "unprognostic (3.53e-1)" "unprognostic (1.24e-2)" "unprognostic (2.41e-1)" "unprognostic (1.47e-2)" "unprognostic (1.26e-1)" "unprognostic (2.23e-1)" "unprognostic (8.05e-2)" MANSC4 ENSG00000205693 "MANSC domain containing 4" A6NHS7 12 27762427-27780236 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "testis: 1.3" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 6.8;Gonadotrophs: 8.1;Müller glia: 7.5;Myonuclei: 6.6;Podocytes: 10.3;Sertoli cells: 31.3" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Podocytes, Testis - Sertoli cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA039454, HPA039682" Uncertain NA NA "Cluster 67: Testis - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" "HPA039454: , HPA039682: " "unprognostic (1.15e-1)" MAOA ENSG00000189221 "Monoamine oxidase A" P21397 X 43654907-43746817 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Catecholamine metabolism, Neurotransmitter degradation" Oxidoreductase "Disease variant, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 206.3" "Cell type enhanced" "Detected in many" "Adipocytes: 378.3;Alveolar cells type 2: 420.3;Basal prostatic cells: 402.5;Enteric transient amplifying cells: 357.0;Enterocytes: 920.0;Medullary thymic epithelial cells: 355.2;Syncytiotrophoblasts: 391.3" "Cell type enhanced" "Detected in many" "endothelial cell: 246.7;pericyte: 107.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 47.6;prostate cancer: 69.7" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Liver - Hepatocytes, Spleen - Fibroblasts_2, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009437, HPA054807, HPA059299" Enhanced Supported Mitochondria,Cytosol No No "Cluster 77: Intestine - Digestion" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 50: Lymphoma - Unknown function" "Cluster 1: Enterocytes - Absorption and Digestion" 4 Mitochondria Cytosol "CAB009437: , HPA054807: , HPA059299: " "unprognostic (7.11e-2)" "unprognostic (5.27e-2)" "unprognostic (1.24e-1)" "unprognostic (9.44e-2)" "unprognostic (1.29e-1)" "unprognostic (1.78e-2)" "unprognostic (5.28e-2)" "unprognostic (4.23e-2)" "unprognostic (3.11e-1)" "unprognostic (4.52e-2)" "potential prognostic favorable (5.86e-4)" "unprognostic (6.34e-3)" "unprognostic (1.23e-1)" "unprognostic (1.34e-1)" "unprognostic (5.16e-2)" "unprognostic (3.29e-3)" "unprognostic (2.82e-2)" "unprognostic (2.23e-1)" "unprognostic (2.68e-1)" "unprognostic (1.25e-1)" "unprognostic (8.83e-2)" "unprognostic (2.19e-1)" "unprognostic (2.44e-1)" "unprognostic (1.04e-1)" "unprognostic (2.90e-1)" "unprognostic (3.04e-3)" "unprognostic (4.16e-1)" "unprognostic (1.70e-2)" "unprognostic (6.12e-2)" "unprognostic (6.87e-2)" "unprognostic (2.75e-1)" MAOB ENSG00000069535 "Monoamine oxidase B" P27338 X 43766610-43882450 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 296.9" "Cell type enhanced" "Detected in many" "Adipocytes: 169.4;Decidual stromal cells: 474.1;Enterocytes: 249.0;Ependymal cells: 250.7;Hepatocytes: 394.4;Mast cells: 276.5;Myonuclei: 481.1;Neuroendocrine cells: 242.5;Other brain neurons: 174.2;Ovarian stromal cells: 241.8;Smooth muscle cells: 174.6" "Cell type enhanced" "Detected in all" "ependymal cell: 315.8" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 147.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 36.5" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Liver - Hepatocytes, Lung - Fibroblasts_1, Prostate - Smooth muscle cells, Spleen - Smooth muscle cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002328, CAB037200" Enhanced NA NA 56000 "Cluster 16: Liver & Kidney - Metabolism" "Cluster 46: Brainstem - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 94: Gonadal somatic cells - Mixed function" 30 "CAB037200: , HPA002328: " "unprognostic (8.68e-3)" "unprognostic (1.12e-2)" "unprognostic (2.66e-1)" "unprognostic (9.16e-2)" "unprognostic (1.32e-1)" "unprognostic (4.20e-2)" "unprognostic (1.90e-2)" "potential prognostic unfavorable (6.66e-5)" "unprognostic (7.49e-2)" "unprognostic (2.04e-1)" "potential prognostic favorable (2.86e-7)" "unprognostic (2.61e-2)" "potential prognostic favorable (7.79e-5)" "unprognostic (1.53e-1)" "unprognostic (6.40e-3)" "unprognostic (1.41e-3)" "unprognostic (3.06e-3)" "unprognostic (3.57e-3)" "unprognostic (1.09e-1)" "unprognostic (6.28e-2)" "unprognostic (1.35e-1)" "unprognostic (1.23e-1)" "unprognostic (1.97e-1)" "unprognostic (8.70e-3)" "potential prognostic unfavorable (3.20e-4)" "unprognostic (3.89e-2)" "unprognostic (1.06e-1)" "unprognostic (8.13e-3)" "unprognostic (3.91e-2)" "unprognostic (2.81e-1)" "potential prognostic favorable (4.37e-4)" MAP10 "KIAA1383, MTR120" ENSG00000212916 "Microtubule associated protein 10" Q9P2G4 1 232805416-232809929 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 15.7;Cone photoreceptor cells: 12.4;Early primary spermatocytes: 11.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052496 Approved NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 61: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" "HPA052496: " "unprognostic (4.06e-2)" "unprognostic (2.80e-1)" "unprognostic (1.15e-1)" "unprognostic (1.58e-1)" "unprognostic (2.25e-1)" "unprognostic (3.46e-2)" "unprognostic (2.58e-2)" "unprognostic (6.30e-2)" "unprognostic (1.08e-1)" "unprognostic (5.11e-2)" "unprognostic (3.12e-1)" "unprognostic (7.45e-2)" "unprognostic (8.60e-2)" "unprognostic (7.16e-3)" "unprognostic (8.60e-3)" "unprognostic (2.33e-1)" "unprognostic (2.56e-2)" "unprognostic (9.83e-3)" "unprognostic (2.40e-1)" "unprognostic (1.16e-1)" MAP1A MAP1L ENSG00000166963 "Microtubule associated protein 1A" P78559 15 43510958-43531620 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 149.9" "Cell type enhanced" "Detected in many" "Corticotrophs: 137.2;Fallopian tube ciliated cells: 98.5;Oligodendrocytes: 77.7;pDCs: 158.3;Peritubular myoid cells: 77.4;Platelets: 329.6;Respiratory ciliated cells: 181.2;Retinal horizontal cells: 124.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 29.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 61 "plasmacytoid DC: 10.5" "Lineage enriched" "Detected in single" 61 "dendritic cells: 10.5" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Lung - Fibroblasts_2, Prostate - Smooth muscle cells, Skin - Fibroblasts_2, Spleen - Fibroblasts_1, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039063, HPA039064, HPA066488" Enhanced Approved "Cytosol,Mid piece,Principal piece" No No 28000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 78: Brain - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 10 Cytosol "Mid piece, Principal piece" "HPA039063: , HPA039064: , HPA066488: " "unprognostic (2.36e-1)" "unprognostic (2.24e-1)" "unprognostic (1.09e-1)" "unprognostic (6.07e-2)" "unprognostic (1.73e-2)" "unprognostic (1.51e-1)" "unprognostic (1.24e-1)" "unprognostic (5.07e-2)" "unprognostic (2.44e-2)" "potential prognostic unfavorable (8.23e-4)" "unprognostic (2.44e-1)" "unprognostic (6.56e-2)" "unprognostic (1.93e-3)" "unprognostic (4.38e-2)" "unprognostic (9.01e-2)" "unprognostic (7.19e-2)" "unprognostic (2.17e-2)" "potential prognostic unfavorable (3.46e-4)" "unprognostic (1.46e-1)" "unprognostic (9.63e-3)" "unprognostic (6.82e-2)" "unprognostic (5.89e-3)" "unprognostic (1.77e-1)" "unprognostic (1.27e-2)" "unprognostic (2.09e-2)" "unprognostic (7.01e-2)" "unprognostic (4.59e-2)" "potential prognostic unfavorable (1.72e-5)" "unprognostic (2.33e-1)" MAP1B "MAP5, PPP1R102" ENSG00000131711 "Microtubule associated protein 1B" P46821 5 72107234-72209565 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 83.8;brain: 116.7;retina: 143.5" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 734.6;Cone photoreceptor cells: 813.6;Epididymal clear cells: 622.6;Other brain neurons: 747.1;Pericytes: 770.7;Pituicytes/FSCs: 728.0;Retinal ganglion cells: 838.2;Rod photoreceptor cells: 580.6;Salivary myoepithelial cells: 507.5;Schwann cells: 548.3;Sertoli cells: 551.0;Smooth muscle cells: 599.9;Vascular smooth muscle cells: 689.7" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 79.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Neuroblastoma: 131.4" "Adrenal gland - Fibroblasts, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009792, HPA022275" Enhanced Supported Supported "Cytosol,Equatorial segment" NA NA 110000 "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 45: Non-specific - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 110: Mural cells - ECM organization" 64 Cytosol "Equatorial segment" "CAB009792: , HPA022275: " "unprognostic (2.61e-1)" "unprognostic (6.67e-2)" "unprognostic (2.51e-1)" "unprognostic (9.36e-2)" "unprognostic (3.37e-2)" "unprognostic (3.94e-2)" "unprognostic (2.85e-2)" "unprognostic (1.16e-2)" "unprognostic (3.37e-2)" "unprognostic (5.66e-2)" "unprognostic (6.02e-3)" "unprognostic (9.07e-2)" "unprognostic (1.71e-2)" "unprognostic (1.09e-1)" "unprognostic (1.65e-1)" "unprognostic (9.68e-3)" "unprognostic (2.73e-3)" "unprognostic (1.54e-1)" "unprognostic (7.62e-2)" "unprognostic (6.88e-2)" "unprognostic (1.61e-2)" "unprognostic (2.25e-3)" "unprognostic (4.27e-2)" "unprognostic (4.31e-2)" "unprognostic (2.10e-3)" "unprognostic (2.50e-1)" "unprognostic (1.82e-1)" "unprognostic (1.15e-2)" "unprognostic (1.14e-1)" "unprognostic (2.76e-2)" "unprognostic (3.26e-1)" MAP1LC3A "ATG8E, LC3, LC3A, MAP1ALC3, MAP1BLC3" ENSG00000101460 "Microtubule associated protein 1 light chain 3 alpha" Q9H492 20 34546854-34560345 "Predicted intracellular proteins" "Autophagy, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 294.9;Late spermatids: 1113.5;Syncytiotrophoblasts: 318.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 7 "neutrophil: 85.9" "Lineage enriched" "Detected in all" 7 "granulocytes: 85.9" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007649, CAB037174, HPA042824, HPA052474, HPA052484" Enhanced Supported "Vesicles,Basal body,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 1: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 95 Vesicles "Basal body, Cytosol" "CAB037174: , HPA007649: , HPA042824: , HPA052474: , HPA052484: " "unprognostic (2.04e-1)" "unprognostic (1.19e-3)" "unprognostic (2.63e-1)" "unprognostic (2.28e-2)" "unprognostic (2.42e-2)" "unprognostic (1.57e-1)" "unprognostic (7.34e-3)" "potential prognostic unfavorable (8.53e-4)" "unprognostic (7.78e-3)" "unprognostic (1.18e-1)" "unprognostic (2.24e-1)" "unprognostic (1.66e-1)" "potential prognostic favorable (2.72e-6)" "unprognostic (6.77e-2)" "unprognostic (3.06e-2)" "unprognostic (1.24e-2)" "unprognostic (2.30e-1)" "unprognostic (1.80e-1)" "unprognostic (3.26e-1)" "unprognostic (3.41e-1)" "unprognostic (4.95e-2)" "potential prognostic favorable (2.08e-4)" "unprognostic (4.42e-2)" "unprognostic (7.51e-3)" "unprognostic (1.07e-1)" "unprognostic (2.27e-2)" "unprognostic (1.75e-1)" "unprognostic (3.84e-1)" "unprognostic (4.23e-2)" "unprognostic (4.42e-3)" "unprognostic (2.57e-1)" MAP1LC3B ATG8F ENSG00000140941 "Microtubule associated protein 1 light chain 3 beta" Q9GZQ8 16 87383953-87404779 "Predicted intracellular proteins" "Autophagy, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 929.3;Neutrophils: 1133.5;Syncytiotrophoblasts: 849.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Liver - Neutrophils, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "CAB037216, HPA042824, HPA052474, HPA052484, HPA053767" Uncertain Supported "Vesicles,Basal body,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 177 Vesicles "Basal body, Cytosol" "CAB037216: , HPA042824: , HPA052474: , HPA052484: , HPA053767: " "unprognostic (2.90e-2)" "unprognostic (9.54e-3)" "unprognostic (2.11e-1)" "unprognostic (4.55e-2)" "unprognostic (4.19e-3)" "unprognostic (1.97e-3)" "unprognostic (8.96e-2)" "unprognostic (1.29e-2)" "unprognostic (7.43e-3)" "unprognostic (6.65e-2)" "potential prognostic favorable (2.93e-6)" "unprognostic (2.83e-2)" "unprognostic (3.70e-3)" "unprognostic (1.01e-3)" "unprognostic (1.20e-2)" "unprognostic (3.26e-1)" "unprognostic (7.84e-2)" "potential prognostic unfavorable (8.59e-5)" "unprognostic (2.40e-2)" "unprognostic (2.00e-1)" "unprognostic (5.25e-2)" "unprognostic (7.56e-2)" "unprognostic (2.16e-3)" "unprognostic (1.36e-1)" "unprognostic (2.77e-1)" "unprognostic (9.79e-2)" "unprognostic (3.75e-2)" "unprognostic (1.28e-2)" "unprognostic (2.68e-1)" "unprognostic (1.53e-1)" "unprognostic (1.58e-2)" MAP1LC3B2 ATG8G ENSG00000258102 "Microtubule associated protein 1 light chain 3 beta 2" A6NCE7 12 116548105-116576606 "Predicted intracellular proteins" "Autophagy, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 5.8" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 16.6;Epididymal basal cells: 20.3;Neutrophils: 42.4;Retinal amacrine cells: 22.2;Retinal horizontal cells: 60.1" "Cell type enhanced" "Detected in many" "upper rhombic lip: 40.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "HPA042824, HPA052474, HPA052484, HPA053767" Uncertain Approved "Vesicles,Basal body,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 71: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 13: Non-specific - Mixed function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 1 Vesicles "Basal body, Cytosol" "HPA042824: , HPA052474: , HPA052484: , HPA053767: " "unprognostic (3.91e-2)" "unprognostic (5.26e-3)" "unprognostic (1.33e-1)" "unprognostic (1.66e-2)" "unprognostic (8.51e-2)" "unprognostic (9.12e-2)" "unprognostic (1.51e-3)" "unprognostic (5.08e-3)" "unprognostic (2.08e-1)" "potential prognostic favorable (3.85e-6)" "unprognostic (4.32e-2)" "unprognostic (4.25e-2)" "potential prognostic unfavorable (1.14e-4)" "unprognostic (1.64e-1)" "unprognostic (4.70e-2)" "unprognostic (9.98e-3)" "unprognostic (4.33e-1)" "unprognostic (9.20e-2)" "unprognostic (1.41e-1)" "unprognostic (3.63e-2)" "unprognostic (2.02e-1)" "unprognostic (1.94e-1)" "unprognostic (3.48e-3)" "unprognostic (2.70e-1)" "unprognostic (1.68e-1)" "unprognostic (1.46e-2)" MAP1LC3C ATG8J ENSG00000197769 "Microtubule associated protein 1 light chain 3 gamma" Q9BXW4 1 241995490-241999098 "Predicted intracellular proteins" "Autophagy, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 12.9;breast: 13.2" "Cell type enhanced" "Detected in some" "Adipocytes: 1.2;Early primary spermatocytes: 1.6;Fibro-adipogenic progenitors: 2.0;Fibroblasts: 3.7;Kupffer cells: 3.1;Myosatellite cells: 1.2;Ovarian stromal cells: 1.4;Retinal amacrine cells: 1.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 9 "testis cancer: 25.8" "Skin - Macrophages, Spleen - Macrophages" "Not detected" "Not detected" HPA072670 Supported "Cytoplasmic bodies" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 48: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 108: Fibroblasts - ECM organization" 67 "Cytoplasmic bodies" "HPA072670: " "unprognostic (1.90e-2)" "unprognostic (5.28e-2)" "potential prognostic unfavorable (1.77e-4)" "unprognostic (9.57e-3)" "potential prognostic unfavorable (5.98e-5)" "unprognostic (1.97e-2)" "unprognostic (1.24e-2)" "unprognostic (2.91e-1)" "unprognostic (1.50e-1)" "unprognostic (2.26e-2)" "unprognostic (2.15e-1)" "unprognostic (1.03e-1)" "unprognostic (1.30e-2)" "unprognostic (7.91e-3)" MAP1S "BPY2IP1, C19orf5, FLJ10669, MAP8, VCY2IP1" ENSG00000130479 "Microtubule associated protein 1S" Q66K74 19 17719242-17734513 "Predicted intracellular proteins" Apoptosis DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Late spermatids: 498.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050934, HPA054637" Approved Supported "Nucleoplasm,Nucleoli,Cytosol,Principal piece" NA NA 9300 "Cluster 7: Non-specific - Innate immune response" "Cluster 67: Testis - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 37 "Cytosol, Principal piece" "Nucleoplasm, Nucleoli" "HPA050934: , HPA054637: " "unprognostic (6.32e-2)" "unprognostic (4.85e-2)" "unprognostic (1.24e-1)" "unprognostic (3.34e-2)" "unprognostic (1.38e-1)" "unprognostic (4.25e-2)" "unprognostic (1.10e-1)" "unprognostic (3.57e-1)" "unprognostic (2.76e-1)" "unprognostic (1.08e-1)" "unprognostic (1.51e-1)" "unprognostic (3.64e-2)" "unprognostic (2.53e-1)" "unprognostic (5.36e-3)" "unprognostic (2.12e-1)" "unprognostic (3.00e-1)" "unprognostic (5.56e-2)" "unprognostic (1.33e-1)" "unprognostic (1.64e-2)" "unprognostic (2.32e-1)" "unprognostic (1.71e-1)" "unprognostic (1.61e-3)" "unprognostic (1.75e-1)" "unprognostic (5.25e-2)" "unprognostic (3.29e-2)" "unprognostic (5.75e-2)" "unprognostic (1.56e-1)" "unprognostic (2.30e-1)" "unprognostic (1.91e-1)" "unprognostic (1.40e-1)" "unprognostic (3.68e-2)" MAP2 "MAP2A, MAP2B, MAP2C" ENSG00000078018 "Microtubule associated protein 2" P11137 2 209424047-209734147 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" Calmodulin-binding "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "brain: 259.5;retina: 379.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 576.4;Bergmann glia: 601.1;Brain excitatory neurons: 919.9;Brain inhibitory neurons: 970.9;Cone photoreceptor cells: 2546.2;Oligodendrocyte progenitor cells: 1122.0;Other brain neurons: 936.3;Pituicytes/FSCs: 1295.2;Rod photoreceptor cells: 1758.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 101.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 63.9" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pituitary gland - Undifferentiated cells (Pituitary gland)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001984, HPA008273, HPA012828" Enhanced Supported Approved "Plasma membrane,Primary cilium,Primary cilium tip,Cytosol" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 7: Liver cancer - Metabolism" "Cluster 79: Photoreceptor cells - Phototransduction" 10 Cytosol "Plasma membrane, Primary cilium, Primary cilium tip" "CAB001984: , HPA008273: , HPA012828: " "unprognostic (1.22e-1)" "unprognostic (3.02e-2)" "unprognostic (9.15e-2)" "unprognostic (1.58e-2)" "unprognostic (9.87e-2)" "unprognostic (5.13e-2)" "unprognostic (1.91e-3)" "unprognostic (1.49e-1)" "unprognostic (1.51e-2)" "validated prognostic favorable (2.05e-5)" "validated prognostic favorable (3.23e-4)" "potential prognostic unfavorable (8.85e-4)" "unprognostic (2.08e-2)" "unprognostic (9.43e-2)" "unprognostic (2.41e-2)" "unprognostic (8.47e-2)" "unprognostic (3.91e-1)" "unprognostic (1.97e-1)" "unprognostic (1.28e-1)" "unprognostic (1.15e-1)" "unprognostic (1.29e-2)" "unprognostic (1.21e-1)" "unprognostic (3.13e-1)" "unprognostic (6.29e-2)" "unprognostic (2.80e-2)" "potential prognostic unfavorable (7.53e-4)" "unprognostic (1.91e-1)" "unprognostic (5.14e-2)" "unprognostic (3.66e-2)" MAP2K1 "MAPKK1, MEK1, PRKMK1" ENSG00000169032 "Mitogen-activated protein kinase kinase 1" Q02750 15 66386837-66491656 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Cardiomyopathy, Disease variant, Ectodermal dysplasia, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "cDC: 568.3;Esophageal apical cells: 779.4;monocytes: 1194.8;Neutrophil progenitors: 560.0;Neutrophils: 799.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003834, HPA026430, CAB080093" Approved Supported "Plasma membrane,Basal body,Cytosol" NA NA 110000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 51: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 69 "Plasma membrane, Cytosol" "Basal body" "CAB003834: , CAB080093: , HPA026430: " "unprognostic (1.16e-2)" "unprognostic (4.36e-3)" "unprognostic (9.52e-2)" "unprognostic (5.73e-3)" "unprognostic (6.40e-2)" "unprognostic (3.65e-1)" "unprognostic (6.05e-3)" "unprognostic (1.65e-1)" "unprognostic (1.96e-3)" "unprognostic (4.30e-2)" "potential prognostic favorable (8.43e-4)" "unprognostic (1.38e-3)" "unprognostic (2.21e-1)" "unprognostic (4.82e-2)" "unprognostic (3.44e-2)" "unprognostic (1.10e-2)" "potential prognostic unfavorable (1.17e-4)" "unprognostic (2.52e-1)" "unprognostic (3.18e-1)" "unprognostic (1.06e-1)" "unprognostic (3.21e-1)" "unprognostic (1.55e-2)" "unprognostic (1.31e-2)" "unprognostic (2.73e-2)" "unprognostic (5.36e-3)" "unprognostic (3.28e-1)" "unprognostic (3.53e-2)" "unprognostic (2.09e-1)" "unprognostic (2.14e-1)" "unprognostic (7.83e-2)" "unprognostic (1.74e-1)" MAP2K2 "MEK2, PRKMK2" ENSG00000126934 "Mitogen-activated protein kinase kinase 2" P36507 19 4090321-4124122 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Cardiomyopathy, Disease variant, Ectodermal dysplasia, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 291.0;Erythrocyte progenitors: 318.8;Esophageal apical cells: 392.2;Late spermatids: 1280.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003835, HPA051993" Supported Enhanced "Cytosol,Mid piece,Principal piece,End piece" NA NA 130000 "Cluster 45: Eosinophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 23: Non-specific - Transcription" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 122 Cytosol "Mid piece, Principal piece, End piece" "CAB003835: , HPA051993: " "unprognostic (1.46e-1)" "unprognostic (1.86e-1)" "unprognostic (1.70e-2)" "potential prognostic favorable (1.87e-4)" "unprognostic (4.76e-2)" "unprognostic (3.72e-1)" "unprognostic (1.81e-1)" "unprognostic (4.85e-2)" "unprognostic (2.14e-2)" "unprognostic (2.64e-1)" "unprognostic (7.34e-2)" "potential prognostic unfavorable (5.03e-5)" "unprognostic (2.20e-2)" "unprognostic (5.07e-3)" "potential prognostic unfavorable (1.42e-6)" "unprognostic (2.50e-2)" "unprognostic (2.98e-1)" "unprognostic (3.05e-1)" "unprognostic (2.42e-1)" "unprognostic (1.97e-1)" "unprognostic (2.18e-1)" "unprognostic (6.44e-2)" "unprognostic (1.30e-1)" "unprognostic (1.49e-1)" "unprognostic (1.28e-1)" "unprognostic (3.68e-2)" "unprognostic (1.55e-1)" "unprognostic (8.17e-3)" "unprognostic (1.01e-2)" "unprognostic (3.26e-1)" "unprognostic (3.15e-2)" MAP2K3 "MAPKK3, MEK3, MKK3, PRKMK3" ENSG00000034152 "Mitogen-activated protein kinase kinase 3" P46734 17 21284672-21315232 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 200.3" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 323.1;Epididymal basal cells: 328.3;Erythrocytes: 384.9;Esophageal apical cells: 331.6;Neutrophils: 734.1;Platelets: 329.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB018548 Approved Approved Nucleoplasm,Cytosol NA NA 18000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 15: Bone marrow - Innate immune response" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 31 "Nucleoplasm, Cytosol" "CAB018548: " "unprognostic (3.80e-1)" "unprognostic (5.40e-2)" "unprognostic (1.01e-2)" "unprognostic (8.46e-2)" "unprognostic (2.53e-1)" "unprognostic (8.57e-2)" "unprognostic (2.56e-3)" "unprognostic (2.30e-2)" "unprognostic (9.08e-2)" "unprognostic (1.10e-1)" "unprognostic (2.53e-3)" "unprognostic (6.17e-3)" "unprognostic (1.73e-1)" "unprognostic (1.10e-1)" "unprognostic (1.26e-1)" "unprognostic (2.82e-2)" "unprognostic (1.85e-1)" "unprognostic (4.31e-2)" "unprognostic (9.10e-2)" "unprognostic (7.23e-3)" "unprognostic (3.75e-2)" "unprognostic (5.31e-2)" "potential prognostic unfavorable (7.60e-5)" "unprognostic (3.51e-2)" "unprognostic (2.71e-1)" "unprognostic (1.17e-1)" "unprognostic (2.91e-2)" "unprognostic (8.81e-2)" "unprognostic (2.23e-1)" "unprognostic (1.14e-1)" "unprognostic (3.16e-2)" MAP2K4 "JNKK1, MEK4, MKK4, PRKMK4, SERK1" ENSG00000065559 "Mitogen-activated protein kinase kinase 4" P45985 17 12020829-12143830 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 564.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 10.5" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in all" 4 "testis cancer: 163.8" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007751, HPA060074" Enhanced Approved "Nucleoplasm,Cell Junctions" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 24: Neurons - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" 27 Nucleoplasm "Cell Junctions" "CAB007751: , HPA060074: " "unprognostic (1.00e-1)" "unprognostic (1.30e-1)" "unprognostic (1.71e-2)" "unprognostic (9.26e-2)" "unprognostic (4.12e-3)" "unprognostic (6.71e-3)" "unprognostic (1.89e-2)" "unprognostic (1.76e-3)" "unprognostic (9.97e-2)" "unprognostic (4.10e-2)" "potential prognostic favorable (2.70e-7)" "unprognostic (1.20e-3)" "unprognostic (1.28e-2)" "unprognostic (2.16e-1)" "unprognostic (1.58e-1)" "unprognostic (2.74e-2)" "unprognostic (8.57e-2)" "unprognostic (2.45e-2)" "unprognostic (5.55e-2)" "unprognostic (2.06e-1)" "unprognostic (1.82e-2)" "unprognostic (4.22e-2)" "potential prognostic unfavorable (9.36e-4)" "unprognostic (5.33e-2)" "unprognostic (4.35e-1)" "unprognostic (4.50e-2)" "unprognostic (1.91e-1)" "unprognostic (2.25e-1)" "unprognostic (2.93e-1)" "unprognostic (3.38e-1)" "unprognostic (8.58e-2)" MAP2K5 "HsT17454, MAPKK5, MEK5, PRKMK5" ENSG00000137764 "Mitogen-activated protein kinase kinase 5" Q13163 15 67542703-67807117 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022094, HPA027347, HPA027755" Supported Approved "Nucleoli,Microtubules,Cytokinetic bridge,Primary cilium,Basal body" Yes NA "Cluster 33: Non-specific - ATP binding" "Cluster 24: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" 26 "Microtubules, Primary cilium" "Nucleoli, Cytokinetic bridge, Basal body" "CAB022094: , HPA027347: , HPA027755: " "unprognostic (2.13e-1)" "unprognostic (1.02e-1)" "unprognostic (1.16e-1)" "unprognostic (6.58e-2)" "unprognostic (3.33e-2)" "unprognostic (1.86e-1)" "unprognostic (2.09e-2)" "unprognostic (5.44e-3)" "unprognostic (1.39e-1)" "unprognostic (2.62e-1)" "validated prognostic favorable (3.83e-6)" "validated prognostic favorable (2.52e-5)" "unprognostic (2.09e-1)" "unprognostic (2.15e-1)" "unprognostic (4.68e-3)" "unprognostic (7.37e-2)" "unprognostic (2.26e-1)" "unprognostic (1.75e-1)" "unprognostic (1.66e-1)" "unprognostic (2.36e-1)" "unprognostic (2.34e-1)" "unprognostic (2.13e-1)" "unprognostic (2.06e-3)" "unprognostic (9.80e-2)" "unprognostic (6.09e-2)" "unprognostic (8.46e-2)" "unprognostic (2.27e-1)" "unprognostic (1.43e-1)" "unprognostic (3.83e-1)" "unprognostic (1.69e-2)" "unprognostic (3.90e-1)" MAP2K6 "MAPKK6, MEK6, MKK6, PRKMK6, SAPKK3" ENSG00000108984 "Mitogen-activated protein kinase kinase 6" P52564 17 69414697-69553865 "Enzymes, Predicted intracellular proteins" "Apoptosis, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 29.8;skeletal muscle: 41.3" "Cell type enhanced" "Detected in many" "Adipocytes: 275.8;Bergmann glia: 652.2;Distal convoluted tubule cells: 199.7;Myonuclei: 557.8;Neutrophils: 214.9" "Cell type enriched" "Detected in all" 4 "Bergmann glia: 648.5" "Cancer enhanced" "Detected in all" "Uterine Corpus Endometrial Carcinoma (TCGA): 41.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "classical monocyte: 22.0;neutrophil: 46.0;plasmacytoid DC: 78.5" "Group enriched" "Detected in all" 9 "dendritic cells: 78.5;granulocytes: 46.0;monocytes: 22.0" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007744, HPA031134" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 22 Nucleoplasm Cytosol "CAB007744: , HPA031134: " "unprognostic (3.08e-1)" "potential prognostic favorable (1.01e-4)" "unprognostic (1.36e-3)" "unprognostic (6.67e-2)" "unprognostic (1.47e-1)" "unprognostic (4.00e-3)" "unprognostic (2.36e-1)" "unprognostic (2.99e-3)" "unprognostic (5.83e-2)" "unprognostic (7.93e-2)" "potential prognostic favorable (6.14e-4)" "unprognostic (4.28e-2)" "unprognostic (1.42e-1)" "unprognostic (4.06e-2)" "unprognostic (1.87e-1)" "unprognostic (2.03e-2)" "unprognostic (3.16e-1)" "unprognostic (9.39e-3)" "potential prognostic favorable (5.54e-4)" "unprognostic (1.95e-2)" "unprognostic (1.40e-1)" "unprognostic (1.81e-3)" "unprognostic (1.08e-1)" "unprognostic (6.90e-2)" "unprognostic (9.13e-2)" "unprognostic (1.97e-2)" "unprognostic (1.51e-1)" "unprognostic (1.78e-1)" "unprognostic (1.35e-1)" "unprognostic (5.68e-3)" "unprognostic (2.68e-1)" MAP2K7 "Jnkk2, MKK7, PRKMK7" ENSG00000076984 "Mitogen-activated protein kinase kinase 7" O14733 19 7903843-7914478 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001633, CAB004262, HPA064711" Supported Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 24: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 23: Non-specific - Transcription" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 27 "Plasma membrane, Cytosol" "CAB004262: , HPA001633: , HPA064711: " "unprognostic (1.61e-3)" "unprognostic (2.36e-1)" "unprognostic (1.03e-2)" "unprognostic (1.75e-1)" "unprognostic (1.01e-1)" "unprognostic (3.34e-2)" "unprognostic (3.02e-2)" "unprognostic (4.85e-2)" "potential prognostic favorable (1.01e-4)" "unprognostic (9.65e-2)" "unprognostic (6.16e-3)" "unprognostic (7.23e-2)" "unprognostic (6.26e-2)" "unprognostic (4.00e-3)" "unprognostic (1.11e-1)" "unprognostic (1.51e-1)" "unprognostic (1.26e-1)" "unprognostic (3.56e-1)" "unprognostic (1.62e-2)" "unprognostic (5.34e-2)" "unprognostic (4.89e-2)" "unprognostic (5.88e-3)" "unprognostic (2.31e-2)" "unprognostic (2.62e-1)" "unprognostic (3.68e-1)" "unprognostic (1.79e-2)" "unprognostic (2.34e-2)" "unprognostic (3.92e-2)" "unprognostic (9.10e-2)" "unprognostic (1.31e-1)" "unprognostic (1.31e-1)" MAP3K1 "MAPKKK1, MEKK, MEKK1" ENSG00000095015 "Mitogen-activated protein kinase kinase kinase 1" Q13233 5 56815549-56896152 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 303.0;Neutrophils: 414.6" "Cell type enhanced" "Detected in all" "oligodendrocyte precursor cell: 299.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "olfactory bulb: 18.2" "Low region specificity" "Detected in all" "CAB004500, HPA046509" Approved Approved Cytosol NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 40: Non-specific - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 6: Leukemia - Signal transduction" "Cluster 24: Neutrophils - Innate immunity signal integration" 45 Cytosol "CAB004500: , HPA046509: " "unprognostic (4.13e-2)" "unprognostic (9.22e-2)" "unprognostic (2.94e-1)" "unprognostic (6.21e-2)" "unprognostic (1.05e-1)" "unprognostic (2.73e-3)" "unprognostic (9.47e-2)" "unprognostic (2.08e-1)" "unprognostic (3.11e-3)" "unprognostic (6.12e-2)" "validated prognostic favorable (2.68e-8)" "validated prognostic favorable (6.14e-5)" "unprognostic (2.05e-1)" "unprognostic (1.46e-1)" "unprognostic (2.11e-1)" "unprognostic (4.01e-2)" "unprognostic (1.61e-1)" "unprognostic (5.47e-2)" "unprognostic (5.97e-2)" "unprognostic (1.56e-2)" "unprognostic (1.50e-1)" "unprognostic (2.11e-2)" "unprognostic (1.08e-1)" "unprognostic (1.14e-1)" "unprognostic (2.93e-2)" "unprognostic (9.05e-2)" "unprognostic (2.53e-1)" "unprognostic (2.05e-1)" "unprognostic (3.91e-1)" "unprognostic (3.50e-2)" "unprognostic (1.58e-1)" MAP3K10 "MEKK10, MLK2, MST" ENSG00000130758 "Mitogen-activated protein kinase kinase kinase 10" Q02779 19 40191426-40215575 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 73.5" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007039 Approved Approved "Nucleoplasm,Actin filaments,Cytosol" NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 15 "Nucleoplasm, Actin filaments, Cytosol" "HPA007039: " "unprognostic (2.58e-1)" "unprognostic (3.44e-1)" "unprognostic (9.07e-2)" "unprognostic (2.60e-1)" "unprognostic (5.70e-3)" "unprognostic (3.65e-1)" "unprognostic (1.51e-1)" "unprognostic (2.97e-1)" "unprognostic (2.69e-2)" "unprognostic (2.58e-1)" "unprognostic (1.50e-1)" "unprognostic (4.03e-2)" "unprognostic (2.78e-1)" "unprognostic (3.77e-3)" "unprognostic (8.81e-3)" "unprognostic (7.47e-2)" "unprognostic (1.47e-1)" "unprognostic (3.28e-1)" "unprognostic (2.89e-1)" "unprognostic (1.35e-2)" "unprognostic (9.13e-2)" "unprognostic (1.62e-2)" "unprognostic (2.21e-2)" "unprognostic (6.12e-2)" "unprognostic (2.06e-2)" "unprognostic (4.20e-2)" "unprognostic (2.54e-1)" "unprognostic (1.65e-1)" "unprognostic (5.77e-2)" "potential prognostic unfavorable (9.92e-4)" "unprognostic (3.21e-2)" MAP3K11 "MEKK11, MLK3, PTK1, SPRK" ENSG00000173327 "Mitogen-activated protein kinase kinase kinase 11" Q16584 11 65597756-65615382 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Enterocytes: 106.5;Late spermatids: 110.3;Neutrophils: 128.7" "Cell type enhanced" "Detected in all" "endothelial cell: 62.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010165 Approved Supported "Centriolar satellite,Cytosol" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 24: Non-specific - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 17 "Centriolar satellite, Cytosol" "CAB010165: " "unprognostic (3.93e-1)" "unprognostic (1.52e-1)" "potential prognostic favorable (1.28e-4)" "unprognostic (1.41e-1)" "unprognostic (2.39e-1)" "unprognostic (9.67e-2)" "unprognostic (1.03e-1)" "unprognostic (5.18e-2)" "unprognostic (3.44e-1)" "unprognostic (1.61e-1)" "unprognostic (2.47e-2)" "unprognostic (7.53e-2)" "unprognostic (3.74e-2)" "unprognostic (2.34e-3)" "unprognostic (3.46e-1)" "unprognostic (8.23e-2)" "unprognostic (6.91e-2)" "unprognostic (2.70e-1)" "unprognostic (2.25e-1)" "unprognostic (2.33e-1)" "potential prognostic favorable (8.33e-4)" "unprognostic (5.29e-2)" "unprognostic (6.03e-2)" "unprognostic (7.24e-2)" "unprognostic (5.38e-2)" "unprognostic (1.31e-1)" "unprognostic (4.15e-1)" "unprognostic (4.90e-2)" "unprognostic (3.77e-2)" "unprognostic (2.87e-1)" "unprognostic (8.87e-2)" MAP3K12 "DLK, MEKK12, MUK, ZPK, ZPKP1" ENSG00000139625 "Mitogen-activated protein kinase kinase kinase 12" Q12852 12 53479669-53500063 "Enzymes, Predicted intracellular proteins, Transporters" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 64.8" "Cell type enhanced" "Detected in many" "Epicardial cells: 116.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 26.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in all" "Rhabdoid: 33.5" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039936, HPA071996" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 8 "Nucleoplasm, Plasma membrane" "HPA039936: , HPA071996: " "unprognostic (1.78e-1)" "unprognostic (1.41e-1)" "unprognostic (1.10e-1)" "unprognostic (1.40e-2)" "unprognostic (2.30e-1)" "unprognostic (2.93e-2)" "potential prognostic unfavorable (6.92e-4)" "unprognostic (2.56e-1)" "unprognostic (1.43e-1)" "unprognostic (2.04e-2)" "unprognostic (1.19e-2)" "potential prognostic unfavorable (4.55e-5)" "unprognostic (2.83e-1)" "unprognostic (8.51e-2)" "potential prognostic favorable (6.78e-5)" "unprognostic (3.74e-1)" "unprognostic (1.73e-2)" "unprognostic (1.57e-1)" "unprognostic (1.13e-1)" "unprognostic (2.66e-1)" "unprognostic (1.93e-3)" "unprognostic (9.59e-2)" "unprognostic (1.75e-2)" "unprognostic (3.03e-2)" "unprognostic (2.10e-1)" "unprognostic (1.97e-1)" "unprognostic (1.37e-3)" "unprognostic (1.04e-1)" "unprognostic (2.65e-1)" "unprognostic (1.47e-1)" MAP3K13 "LZK, MEKK13" ENSG00000073803 "Mitogen-activated protein kinase kinase kinase 13" O43283 3 185282941-185489094 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016497, HPA036691, HPA036692" Uncertain Approved "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 18: Non-specific - Translation" "Cluster 36: Brain & Liver - Signaling" "Cluster 37: Neurons - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 18: Adrenal cortex cells - Steroidogensis" 2 "Centriolar satellite" "Nucleoplasm, Cytosol" "HPA016497: , HPA036691: , HPA036692: " "unprognostic (5.46e-2)" "unprognostic (1.36e-1)" "unprognostic (3.94e-1)" "unprognostic (1.17e-1)" "unprognostic (1.83e-2)" "unprognostic (1.28e-1)" "unprognostic (9.71e-2)" "potential prognostic favorable (2.15e-5)" "unprognostic (1.39e-1)" "unprognostic (1.15e-2)" "potential prognostic favorable (1.34e-5)" "unprognostic (1.86e-2)" "unprognostic (3.20e-2)" "unprognostic (7.89e-3)" "unprognostic (9.59e-3)" "unprognostic (4.42e-1)" "unprognostic (1.08e-2)" "unprognostic (7.09e-3)" "unprognostic (4.00e-3)" "potential prognostic favorable (7.09e-4)" "unprognostic (1.33e-1)" "potential prognostic unfavorable (3.85e-4)" "unprognostic (5.28e-2)" "unprognostic (2.54e-3)" "unprognostic (2.20e-1)" "unprognostic (6.56e-2)" "unprognostic (3.60e-2)" "unprognostic (2.73e-2)" "unprognostic (1.34e-1)" "unprognostic (9.64e-2)" "unprognostic (1.22e-1)" MAP3K14 "FTDCR1B, HS, HSNIK, NIK" ENSG00000006062 "Mitogen-activated protein kinase kinase kinase 14" Q99558 17 45263119-45317029 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 141.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 88.8" "Spleen - B-cells (Spleen), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA027269, HPA027270" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 82: Dendritic cells - Antigen presentation" 72 "Vesicles, Cytosol" "Nucleoplasm, Nucleoli fibrillar center" "HPA027269: , HPA027270: " "unprognostic (5.65e-2)" "unprognostic (3.28e-1)" "unprognostic (2.07e-2)" "unprognostic (2.53e-2)" "unprognostic (2.13e-1)" "unprognostic (1.43e-1)" "unprognostic (1.25e-1)" "unprognostic (3.03e-3)" "unprognostic (5.57e-3)" "unprognostic (1.20e-1)" "potential prognostic favorable (1.05e-4)" "unprognostic (6.54e-2)" "unprognostic (1.32e-2)" "unprognostic (6.69e-2)" "unprognostic (2.80e-2)" "unprognostic (1.18e-1)" "unprognostic (3.78e-1)" "unprognostic (2.24e-2)" "unprognostic (7.16e-2)" "unprognostic (2.28e-1)" "unprognostic (8.45e-3)" "unprognostic (2.15e-1)" "potential prognostic unfavorable (2.46e-4)" "unprognostic (1.26e-1)" "unprognostic (2.76e-2)" "unprognostic (1.78e-3)" "unprognostic (1.42e-1)" "unprognostic (6.92e-2)" "unprognostic (3.18e-1)" "unprognostic (1.41e-1)" "unprognostic (4.23e-2)" MAP3K15 "ASK3, bA723P2.3, FLJ16518" ENSG00000180815 "Mitogen-activated protein kinase kinase kinase 15" Q6ZN16 X 19360056-19515508 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "adrenal gland: 9.8;choroid plexus: 4.3" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 493.7;Cardiomyocytes: 57.6;Choroid plexus epithelial cells: 316.3;Distal convoluted tubule cells: 107.9;Renal collecting duct principal cells: 76.7;Renal connecting tubule cells: 83.9" "Cell type enriched" "Detected in all" 18 "choroid plexus epithelial cell: 213.4" "Not detected" "Not detected" "Region enriched" "Detected in some" 17 "choroid plexus: 27.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "testis cancer: 3.4" "Kidney - Ascending Loop of Henle cells, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Alpha cells, Pituitary gland - Somatotropes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA004006 Approved Vesicles NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 36: Choroid plexus - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 18: Adrenal cortex cells - Steroidogensis" 1 Vesicles "HPA004006: " "unprognostic (2.14e-1)" "unprognostic (3.78e-3)" MAP3K19 "FLJ23074, RCK, YSK4" ENSG00000176601 "Mitogen-activated protein kinase kinase kinase 19" Q56UN5 2 134964485-135047468 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 8.5;fallopian tube: 17.0" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 89.5;Cone photoreceptor cells: 89.0;Early spermatids: 94.7;Endometrial ciliated cells: 191.4;Ependymal cells: 474.7;Epididymal efferent duct ciliated cells: 156.1;Fallopian tube ciliated cells: 225.9;Late spermatids: 252.6;Respiratory ciliated cells: 379.5" "Cell type enriched" "Detected in many" 6 "ependymal cell: 509.7" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011388 Uncertain Cytosol NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 1: Neuronal - Visual perception" "Cluster 34: Ciliated cells - Cilia assembly & function" Cytosol "HPA011388: " "unprognostic (8.64e-2)" "unprognostic (7.23e-2)" "unprognostic (7.92e-2)" "unprognostic (7.56e-2)" "unprognostic (4.12e-1)" MAP3K2 "MEKK2, MEKK2B" ENSG00000169967 "Mitogen-activated protein kinase kinase kinase 2" Q9Y2U5 2 127298668-127388465 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in all" 4 "Neutrophils: 2588.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 8.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021540 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 42 "Nucleoplasm, Cytosol" "HPA021540: " "unprognostic (5.68e-2)" "unprognostic (7.72e-2)" "unprognostic (3.65e-2)" "unprognostic (1.09e-1)" "unprognostic (1.96e-1)" "unprognostic (2.89e-2)" "unprognostic (2.81e-1)" "unprognostic (4.36e-1)" "unprognostic (1.87e-1)" "unprognostic (4.10e-3)" "potential prognostic favorable (2.72e-5)" "unprognostic (1.84e-2)" "unprognostic (2.81e-2)" "unprognostic (5.40e-2)" "unprognostic (4.47e-1)" "unprognostic (3.24e-1)" "unprognostic (8.58e-2)" "unprognostic (1.52e-1)" "unprognostic (9.92e-2)" "unprognostic (1.00e-1)" "unprognostic (5.53e-3)" "unprognostic (6.61e-2)" "unprognostic (2.13e-2)" "unprognostic (1.07e-1)" "unprognostic (3.23e-2)" "unprognostic (2.30e-3)" "unprognostic (2.70e-1)" "unprognostic (3.16e-1)" "unprognostic (1.91e-1)" "unprognostic (1.14e-2)" "unprognostic (1.26e-1)" MAP3K20 "MLK7, MLTK, MLTKalpha, MLTKbeta, MRK, ZAK" ENSG00000091436 "Mitogen-activated protein kinase kinase kinase 20" Q9NYL2 2 173075435-173268015 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Kinase, RNA-binding, rRNA-binding, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 245.3;tongue: 261.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 463.9;Myonuclei: 1066.6;Smooth muscle cells: 506.8;Thymic myoid cells: 683.9;Vascular smooth muscle cells: 464.5" "Cell type enhanced" "Detected in all" "pericyte: 340.7;vascular associated smooth muscle cell: 651.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 15.6" "Group enriched" "Detected in many" 5 "dendritic cells: 15.6;monocytes: 9.4" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Endothelial cells, Prostate - Smooth muscle cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017205 Approved Supported Cytosol NA Yes "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 44: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 28 Cytosol "HPA017205: " "unprognostic (7.23e-2)" "unprognostic (3.53e-3)" "unprognostic (1.02e-2)" "unprognostic (9.37e-2)" "unprognostic (6.39e-2)" "unprognostic (1.36e-1)" "potential prognostic unfavorable (6.56e-5)" "unprognostic (1.61e-1)" "unprognostic (4.20e-3)" "unprognostic (9.78e-2)" "unprognostic (2.15e-3)" "unprognostic (1.21e-2)" "unprognostic (5.08e-2)" "unprognostic (2.94e-3)" "unprognostic (5.06e-3)" "unprognostic (5.27e-2)" "unprognostic (9.37e-2)" "unprognostic (1.10e-1)" "unprognostic (1.03e-1)" "unprognostic (2.57e-2)" "unprognostic (3.05e-2)" "unprognostic (1.87e-1)" "unprognostic (2.83e-3)" "unprognostic (9.20e-3)" "unprognostic (3.09e-2)" "unprognostic (2.53e-1)" "unprognostic (1.91e-1)" "unprognostic (1.53e-1)" "unprognostic (2.82e-1)" MAP3K21 "KIAA1804, MLK4" ENSG00000143674 "Mitogen-activated protein kinase kinase kinase 21" Q5TCX8 1 233327724-233385148 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 19.1" "Cell type enhanced" "Detected in many" "Pancreatic acinar cells: 109.0;Pancreatic duct cells: 142.1;Parietal cells: 145.0;Proximal tubule cells: 107.3;Renal collecting duct principal cells: 166.2;Renal connecting tubule cells: 244.5;Sertoli cells: 243.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "NK-cell: 1.6" "Lineage enriched" "Detected in single" 5 "NK-cells: 1.6" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Testis - Sertoli cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA007636 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 88: Proximal tubular cells - Transmembrane transport" 34 "Plasma membrane, Cytosol" "HPA007636: " "unprognostic (2.74e-1)" "unprognostic (1.81e-1)" "unprognostic (3.26e-2)" "unprognostic (2.79e-1)" "unprognostic (1.05e-1)" "unprognostic (1.65e-2)" "unprognostic (1.44e-1)" "unprognostic (8.47e-2)" "unprognostic (6.48e-2)" "unprognostic (6.34e-2)" "unprognostic (2.26e-2)" "unprognostic (3.64e-2)" "unprognostic (6.08e-2)" "unprognostic (2.43e-1)" "unprognostic (1.75e-1)" "potential prognostic favorable (1.05e-4)" "unprognostic (1.05e-1)" "unprognostic (3.42e-1)" "unprognostic (1.46e-1)" "unprognostic (1.88e-1)" "unprognostic (1.36e-1)" "unprognostic (2.49e-2)" "unprognostic (1.86e-1)" "unprognostic (1.37e-1)" "unprognostic (9.44e-2)" "unprognostic (8.54e-2)" "unprognostic (7.27e-2)" MAP3K3 "MAPKKK3, MEKK3" ENSG00000198909 "Mitogen-activated protein kinase kinase kinase 3" Q99759 17 63622415-63696305 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 557.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007764, HPA035410, HPA035411, HPA064376" Uncertain Approved Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 25: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" 50 Nucleoplasm "CAB007764: , HPA035410: , HPA035411: , HPA064376: " "potential prognostic favorable (6.64e-4)" "unprognostic (9.42e-3)" "unprognostic (3.29e-3)" "unprognostic (2.35e-2)" "unprognostic (8.37e-2)" "unprognostic (2.34e-2)" "unprognostic (1.95e-2)" "potential prognostic favorable (2.84e-4)" "unprognostic (1.99e-2)" "unprognostic (3.60e-1)" "unprognostic (1.56e-3)" "unprognostic (3.05e-3)" "unprognostic (3.54e-1)" "unprognostic (5.78e-3)" "unprognostic (4.57e-2)" "unprognostic (8.72e-3)" "unprognostic (2.08e-2)" "unprognostic (5.99e-2)" "unprognostic (8.29e-2)" "unprognostic (2.54e-2)" "unprognostic (1.73e-1)" "unprognostic (2.26e-2)" "unprognostic (5.45e-2)" "unprognostic (1.43e-1)" "unprognostic (3.88e-1)" "unprognostic (1.51e-3)" "unprognostic (3.47e-1)" "unprognostic (4.43e-2)" "unprognostic (1.60e-1)" "unprognostic (2.94e-1)" "unprognostic (9.84e-2)" MAP3K4 "KIAA0213, MAPKKK4, MEKK4, MTK1" ENSG00000085511 "Mitogen-activated protein kinase kinase kinase 4" Q9Y6R4 6 160991727-161117385 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Thyrotrophs: 308.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 31.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007625 Uncertain Approved Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 9: T-cells - Adaptive immunity: Regulation" 29 Cytosol "HPA007625: " "unprognostic (3.26e-1)" "unprognostic (5.29e-3)" "unprognostic (1.03e-1)" "potential prognostic unfavorable (7.85e-4)" "unprognostic (1.10e-1)" "unprognostic (3.20e-2)" "unprognostic (4.13e-2)" "potential prognostic favorable (2.24e-4)" "unprognostic (2.03e-1)" "unprognostic (2.22e-2)" "potential prognostic favorable (1.85e-8)" "unprognostic (1.65e-3)" "unprognostic (1.22e-1)" "unprognostic (4.60e-2)" "unprognostic (1.39e-2)" "unprognostic (9.16e-2)" "unprognostic (8.15e-2)" "unprognostic (2.25e-1)" "unprognostic (7.29e-2)" "unprognostic (3.39e-2)" "unprognostic (1.70e-1)" "unprognostic (3.75e-1)" "potential prognostic unfavorable (7.62e-5)" "unprognostic (1.36e-1)" "unprognostic (7.76e-3)" "unprognostic (1.18e-2)" "unprognostic (3.57e-1)" "unprognostic (2.33e-1)" "unprognostic (1.34e-1)" "unprognostic (7.85e-2)" "unprognostic (2.25e-1)" MAP3K5 "ASK1, MAPKKK5, MEKK5" ENSG00000197442 "Mitogen-activated protein kinase kinase kinase 5" Q99683 6 136557046-136793097 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Immunity, Innate immunity, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 83.2" "Cell type enhanced" "Detected in all" "Adrenal cortex cells: 2392.7;Neutrophils: 1381.5;Pituicytes/FSCs: 1412.2;Prostatic glandular cells: 895.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007824, HPA063245" Supported Supported Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 55: Lymphoma - Immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 102 Cytosol "CAB007824: , HPA063245: " "unprognostic (1.84e-2)" "unprognostic (1.09e-1)" "unprognostic (3.71e-1)" "unprognostic (6.58e-2)" "unprognostic (4.73e-2)" "unprognostic (1.70e-1)" "unprognostic (2.11e-1)" "unprognostic (3.26e-1)" "unprognostic (1.63e-3)" "unprognostic (2.45e-1)" "potential prognostic favorable (2.25e-6)" "unprognostic (2.27e-2)" "unprognostic (1.48e-1)" "unprognostic (1.44e-1)" "potential prognostic favorable (7.48e-4)" "unprognostic (1.50e-1)" "unprognostic (1.95e-2)" "unprognostic (7.31e-2)" "unprognostic (4.66e-3)" "unprognostic (2.03e-2)" "unprognostic (4.71e-2)" "unprognostic (1.11e-3)" "unprognostic (3.01e-1)" "unprognostic (2.43e-1)" "unprognostic (4.11e-2)" "unprognostic (6.78e-2)" "unprognostic (1.26e-1)" "unprognostic (3.71e-1)" "unprognostic (2.25e-1)" "unprognostic (5.47e-2)" "unprognostic (1.43e-2)" MAP3K6 "ASK2, MAPKKK6, MEKK6" ENSG00000142733 "Mitogen-activated protein kinase kinase kinase 6" O95382 1 27355184-27366961 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 41.3;Esophageal basal cells: 30.7;Esophageal suprabasal cells: 36.7;Vascular endothelial cells: 39.4" "Cell type enhanced" "Detected in many" "endothelial cell: 15.8;vascular associated smooth muscle cell: 16.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Pancreas - Endothelial cells, Pituitary gland - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" HPA051192 Approved Approved "Nucleoplasm,Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 58: Skin - Keratinization" "Cluster 44: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 4 Nucleoplasm "Plasma membrane, Actin filaments, Cytosol" "HPA051192: " "unprognostic (1.80e-1)" "unprognostic (1.70e-2)" "unprognostic (8.91e-2)" "unprognostic (4.28e-2)" "unprognostic (1.36e-1)" "unprognostic (5.86e-2)" "potential prognostic unfavorable (7.90e-5)" "unprognostic (6.29e-2)" "unprognostic (2.24e-3)" "unprognostic (3.95e-2)" "unprognostic (3.56e-3)" "unprognostic (1.37e-1)" "unprognostic (1.59e-1)" "unprognostic (2.57e-2)" "unprognostic (8.50e-2)" "unprognostic (4.89e-2)" "unprognostic (1.11e-1)" "unprognostic (2.28e-1)" "unprognostic (1.67e-1)" "unprognostic (8.37e-2)" "unprognostic (6.75e-2)" "unprognostic (1.21e-2)" "unprognostic (5.39e-2)" "unprognostic (6.60e-2)" "potential prognostic unfavorable (1.03e-5)" "unprognostic (5.78e-2)" "unprognostic (1.27e-1)" "unprognostic (9.77e-2)" "unprognostic (9.67e-2)" "unprognostic (4.66e-3)" "unprognostic (9.67e-2)" MAP3K7 "MEKK7, TAK1" ENSG00000135341 "Mitogen-activated protein kinase kinase kinase 7" O43318 6 90513573-90587086 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007633, HPA075335" Approved Supported "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 7: Non-specific - Transcription" 108 Cytosol "Nuclear speckles, Plasma membrane" "HPA007633: , HPA075335: " "unprognostic (1.28e-1)" "unprognostic (1.26e-2)" "unprognostic (1.16e-3)" "unprognostic (6.96e-3)" "unprognostic (7.22e-2)" "unprognostic (4.36e-2)" "unprognostic (1.62e-1)" "unprognostic (3.48e-2)" "unprognostic (3.03e-1)" "unprognostic (7.73e-3)" "unprognostic (6.42e-2)" "unprognostic (1.22e-1)" "unprognostic (1.82e-1)" "potential prognostic unfavorable (6.81e-5)" "unprognostic (4.18e-2)" "unprognostic (2.31e-2)" "unprognostic (1.06e-1)" "unprognostic (1.67e-1)" "unprognostic (1.17e-1)" "unprognostic (2.32e-1)" "unprognostic (3.44e-1)" "unprognostic (7.60e-2)" "unprognostic (1.02e-2)" "unprognostic (3.75e-1)" "unprognostic (1.74e-2)" "unprognostic (7.38e-2)" "unprognostic (3.01e-2)" "unprognostic (7.14e-2)" "unprognostic (4.73e-1)" "unprognostic (2.87e-1)" "unprognostic (1.74e-1)" MAP3K7CL "C21orf7, TAK1L, TAKL, TAKL-1, TAKL-2, TAKL-4" ENSG00000156265 "MAP3K7 C-terminal like" P57077 21 29077471-29175889 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 36.5;tongue: 42.6" "Cell type enriched" "Detected in many" 6 "Platelets: 739.8" "Cell type enhanced" "Detected in all" "vascular associated smooth muscle cell: 73.8" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 31.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 52.9" "Group enriched" "Detected in all" 8 "B-cells: 22.9;granulocytes: 52.9;monocytes: 14.1" "Cancer enhanced" "Detected in all" "Kidney cancer: 34.4;Sarcoma: 37.8" "Not detected" "Not detected" "HPA030079, HPA042439" Uncertain Approved Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 47: Platelets - Hemostasis" 3 Nucleoplasm "HPA030079: , HPA042439: " "unprognostic (3.26e-1)" "unprognostic (3.60e-2)" "unprognostic (5.96e-2)" "unprognostic (4.88e-3)" "unprognostic (9.12e-2)" "unprognostic (2.37e-2)" "unprognostic (3.17e-3)" "unprognostic (4.59e-2)" "unprognostic (7.78e-2)" "unprognostic (5.29e-2)" "unprognostic (9.03e-2)" "unprognostic (3.96e-1)" "unprognostic (1.19e-2)" "unprognostic (2.76e-2)" "unprognostic (4.39e-2)" "unprognostic (8.18e-2)" "unprognostic (6.99e-2)" "unprognostic (7.49e-2)" "unprognostic (5.83e-2)" "unprognostic (4.42e-3)" "unprognostic (1.63e-1)" "unprognostic (2.99e-2)" "unprognostic (3.29e-1)" "unprognostic (2.70e-1)" "unprognostic (2.95e-1)" "unprognostic (1.32e-3)" "unprognostic (6.06e-2)" "unprognostic (1.26e-1)" "unprognostic (4.92e-1)" MAP3K8 "c-COT, COT, EST, ESTF, MEKK8, Tpl-2" ENSG00000107968 "Mitogen-activated protein kinase kinase kinase 8" P41279 10 30434021-30461833 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Immunity" "Kinase, Serine/threonine-protein kinase, Transferase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "bone marrow: 313.3" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 486.6;Endometrial luminal cells: 501.1;Hofbauer cells: 515.3;Innate lymphoid cells: 548.2;Kupffer cells: 463.3;monocytes: 842.3;Neutrophils: 683.0;Urothelial cells: 542.9" "Cell type enhanced" "Detected in many" "endothelial cell: 166.1;leukocyte: 104.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Neutrophils, Liver - Neutrophils" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB005120, HPA017962" Supported Supported Cytosol NA NA "Cluster 32: Basophils - Transcription" "Cluster 15: Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 55: Lymphoma - Immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 17 Cytosol "CAB005120: , HPA017962: " "unprognostic (2.09e-2)" "unprognostic (5.47e-2)" "unprognostic (4.98e-2)" "unprognostic (9.51e-2)" "unprognostic (1.10e-1)" "unprognostic (2.72e-1)" "unprognostic (1.83e-2)" "unprognostic (2.12e-1)" "unprognostic (2.78e-2)" "unprognostic (5.12e-3)" "potential prognostic unfavorable (7.94e-5)" "unprognostic (1.06e-1)" "unprognostic (1.06e-1)" "unprognostic (6.53e-2)" "unprognostic (2.83e-1)" "unprognostic (1.05e-2)" "unprognostic (4.24e-2)" "unprognostic (8.25e-2)" "unprognostic (8.96e-2)" "unprognostic (5.11e-2)" "unprognostic (2.81e-2)" "unprognostic (1.01e-1)" "unprognostic (7.49e-3)" "unprognostic (1.70e-1)" "unprognostic (1.50e-1)" "potential prognostic favorable (7.20e-5)" "unprognostic (3.29e-1)" "unprognostic (1.46e-1)" "unprognostic (6.97e-2)" "unprognostic (3.08e-3)" "unprognostic (3.62e-2)" MAP3K9 "MEKK9, MLK1, PRKE1" ENSG00000006432 "Mitogen-activated protein kinase kinase kinase 9" P80192 14 70722526-70809534 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.6" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 266.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Kidney - Macrophages, Lung - Alveolar cells type 2, Skin - Keratinocyte (granular), Spleen - B-cells (Spleen), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000942 Approved Approved Nucleoplasm,Nucleoli "Intracellular and membrane" Transcription NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 13 "Nucleoplasm, Nucleoli" "HPA000942: " "unprognostic (4.81e-2)" "unprognostic (4.95e-2)" "unprognostic (3.93e-1)" "unprognostic (7.20e-2)" "unprognostic (8.18e-2)" "unprognostic (7.44e-2)" "unprognostic (3.39e-1)" "unprognostic (5.86e-2)" "unprognostic (4.10e-2)" "unprognostic (9.17e-2)" "unprognostic (1.61e-1)" "unprognostic (4.45e-2)" "unprognostic (6.09e-2)" "unprognostic (1.18e-2)" "unprognostic (1.42e-1)" "unprognostic (3.74e-2)" "unprognostic (1.77e-1)" "unprognostic (6.90e-2)" "unprognostic (2.92e-2)" "unprognostic (2.66e-2)" "unprognostic (1.26e-1)" "potential prognostic unfavorable (1.15e-4)" "unprognostic (3.37e-1)" "unprognostic (2.15e-2)" "unprognostic (9.14e-2)" "unprognostic (2.45e-1)" "unprognostic (1.73e-1)" MAP4 ENSG00000047849 "Microtubule associated protein 4" P27816 3 47850690-48089272 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 890.0;skeletal muscle: 562.4" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 1467.7;Myonuclei: 2090.4;Thymic myoid cells: 964.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038149, HPA038150" Enhanced Approved "Plasma membrane,Microtubules,Primary cilium,Basal body,Cytosol,Acrosome,Equatorial segment" NA NA 600000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 75 "Plasma membrane, Microtubules, Primary cilium, Cytosol" "Basal body, Acrosome, Equatorial segment" "HPA038149: , HPA038150: " "unprognostic (3.70e-2)" "unprognostic (1.77e-1)" "unprognostic (9.34e-2)" "unprognostic (6.10e-3)" "unprognostic (1.09e-1)" "unprognostic (7.42e-2)" "unprognostic (2.75e-1)" "unprognostic (5.11e-2)" "unprognostic (2.74e-1)" "unprognostic (3.76e-3)" "unprognostic (3.31e-3)" "unprognostic (3.68e-2)" "potential prognostic favorable (6.40e-4)" "potential prognostic unfavorable (1.67e-4)" "unprognostic (1.26e-2)" "unprognostic (8.11e-2)" "potential prognostic unfavorable (2.11e-4)" "unprognostic (3.61e-2)" "unprognostic (7.13e-2)" "unprognostic (3.87e-2)" "unprognostic (9.64e-2)" "unprognostic (6.07e-2)" "unprognostic (7.45e-2)" "unprognostic (6.59e-2)" "unprognostic (1.69e-1)" "unprognostic (2.26e-3)" "unprognostic (3.22e-1)" "unprognostic (9.14e-2)" "unprognostic (1.30e-1)" "unprognostic (1.17e-1)" "unprognostic (2.90e-2)" MAP4K1 HPK1 ENSG00000104814 "Mitogen-activated protein kinase kinase kinase kinase 1" Q92918 19 38587641-38618882 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 28.3;lymphoid tissue: 55.1" "Cell type enhanced" "Detected in some" "B-cells: 31.2;cDC: 30.7;Microglia: 18.2;NK-cells: 18.4;Oocytes: 73.7;pDCs: 31.8;Plasma cells: 20.6;Rod photoreceptor cells: 45.4;T-cells: 30.1;Thymocytes: 15.2" "Group enriched" "Detected in many" 7 "central nervous system macrophage: 22.0;leukocyte: 48.2" "Cancer enriched" "Detected in many" 4 "Testicular Germ Cell Tumor (TCGA): 14.8" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 26 "Leukemia: 17.7;lymphoma: 54.5;Myeloma: 29.8" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Prostate - T-cells, Spleen - B-cells (Spleen), Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA007419, CAB007754" Enhanced Approved "Plasma membrane" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 79: Photoreceptor cells - Phototransduction" 31 "Plasma membrane" "CAB007754: , HPA007419: " "unprognostic (1.97e-2)" "unprognostic (4.78e-3)" "unprognostic (1.40e-2)" "potential prognostic favorable (5.27e-4)" "unprognostic (4.83e-2)" "unprognostic (1.57e-1)" "unprognostic (7.43e-3)" "unprognostic (4.01e-2)" "potential prognostic favorable (9.20e-4)" "unprognostic (1.35e-2)" "unprognostic (1.46e-1)" "unprognostic (1.13e-1)" "unprognostic (3.49e-2)" "unprognostic (1.98e-3)" "unprognostic (2.78e-3)" "unprognostic (2.23e-1)" "unprognostic (1.47e-1)" "unprognostic (2.24e-1)" "unprognostic (4.92e-2)" "unprognostic (2.09e-2)" "unprognostic (3.37e-2)" "unprognostic (8.10e-3)" "unprognostic (9.24e-2)" "unprognostic (2.46e-2)" "unprognostic (4.19e-2)" "unprognostic (1.71e-1)" "unprognostic (2.75e-1)" "unprognostic (5.25e-2)" "unprognostic (5.74e-2)" "unprognostic (2.84e-1)" MAP4K2 "BL44, GCK, RAB8IP" ENSG00000168067 "Mitogen-activated protein kinase kinase kinase kinase 2" Q12851 11 64784918-64803241 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hematopoietic stem cells: 45.1;Late spermatids: 55.0;Lymphatic endothelial cells: 74.5;Platelets: 85.9" "Cell type enriched" "Detected in all" 4 "endothelial cell: 115.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007330 Enhanced Approved Vesicles NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 10 Vesicles "HPA007330: " "unprognostic (1.70e-1)" "unprognostic (1.06e-1)" "unprognostic (1.81e-2)" "unprognostic (2.24e-1)" "unprognostic (2.57e-3)" "unprognostic (3.32e-2)" "unprognostic (1.43e-1)" "unprognostic (2.01e-2)" "unprognostic (8.35e-2)" "unprognostic (1.32e-1)" "potential prognostic favorable (4.97e-5)" "unprognostic (6.92e-2)" "unprognostic (3.71e-2)" "unprognostic (2.64e-3)" "unprognostic (2.61e-1)" "unprognostic (3.26e-1)" "unprognostic (1.84e-2)" "unprognostic (2.04e-3)" "unprognostic (6.69e-2)" "unprognostic (1.86e-2)" "unprognostic (7.07e-2)" "unprognostic (1.48e-1)" "unprognostic (3.84e-2)" "unprognostic (4.29e-1)" "unprognostic (1.54e-1)" "unprognostic (3.91e-1)" "unprognostic (2.14e-1)" "unprognostic (2.53e-2)" "unprognostic (3.85e-2)" "unprognostic (1.02e-1)" "unprognostic (2.57e-2)" MAP4K3 "GLK, MAPKKKK3, RAB8IPL1" ENSG00000011566 "Mitogen-activated protein kinase kinase kinase kinase 3" Q8IVH8 2 39249266-39437301 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial glandular cells: 1313.0;Myonuclei: 1183.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030380 Approved Approved "Centriolar satellite" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 31: Non-specific - Transcription" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 51: Secretory epithelial cells - Mixed function" 11 "Centriolar satellite" "HPA030380: " "unprognostic (1.25e-1)" "unprognostic (3.45e-2)" "unprognostic (6.93e-2)" "unprognostic (1.10e-1)" "unprognostic (6.48e-2)" "unprognostic (2.12e-1)" "unprognostic (1.29e-1)" "unprognostic (6.27e-2)" "unprognostic (1.89e-1)" "unprognostic (1.22e-1)" "potential prognostic favorable (2.59e-4)" "unprognostic (5.32e-2)" "unprognostic (2.01e-2)" "unprognostic (2.83e-3)" "unprognostic (4.32e-3)" "unprognostic (8.03e-2)" "unprognostic (1.76e-2)" "unprognostic (2.41e-2)" "unprognostic (3.60e-2)" "unprognostic (2.23e-2)" "unprognostic (9.99e-3)" "unprognostic (9.56e-3)" "unprognostic (5.75e-3)" "unprognostic (5.68e-2)" "unprognostic (3.30e-2)" "unprognostic (1.51e-2)" "unprognostic (1.08e-1)" "unprognostic (2.76e-2)" "unprognostic (4.20e-1)" "unprognostic (9.02e-2)" "unprognostic (3.01e-1)" MAP4K4 "FLH21957, HGK, NIK" ENSG00000071054 "Mitogen-activated protein kinase kinase kinase kinase 4" O95819 2 101696850-101894690 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 230.3" "Cell type enhanced" "Detected in all" "Microglia: 1110.6;monocytes: 820.0;Neutrophils: 3043.0;Oligodendrocytes: 1371.9;Retinal ganglion cells: 1054.5" "Cell type enhanced" "Detected in all" "oligodendrocyte: 1850.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008476 Uncertain NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 72: Neuronal - Signal transduction" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 58 "HPA008476: " "unprognostic (1.21e-2)" "unprognostic (6.97e-2)" "unprognostic (1.68e-2)" "unprognostic (2.64e-3)" "unprognostic (2.84e-1)" "unprognostic (1.85e-3)" "unprognostic (1.85e-1)" "unprognostic (3.27e-1)" "unprognostic (5.61e-2)" "unprognostic (2.83e-2)" "unprognostic (5.89e-3)" "unprognostic (3.70e-2)" "unprognostic (3.02e-2)" "unprognostic (5.80e-3)" "unprognostic (2.20e-2)" "unprognostic (4.52e-3)" "potential prognostic unfavorable (2.70e-5)" "unprognostic (2.33e-2)" "unprognostic (3.10e-1)" "unprognostic (9.34e-2)" "unprognostic (8.83e-3)" "unprognostic (1.21e-3)" "potential prognostic unfavorable (5.78e-7)" "unprognostic (3.02e-2)" "unprognostic (6.60e-2)" "unprognostic (5.33e-2)" "unprognostic (7.99e-2)" "unprognostic (1.06e-2)" "unprognostic (4.93e-1)" "unprognostic (8.90e-2)" "unprognostic (7.97e-2)" MAP4K5 "GCKR, KHS, KHS1" ENSG00000012983 "Mitogen-activated protein kinase kinase kinase kinase 5" Q9Y4K4 14 50418501-50561126 "Enzymes, Essential proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 906.8" "Cell type enhanced" "Detected in all" "oligodendrocyte: 1145.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 18.9;eosinophil: 5.5" "Lineage enriched" "Detected in many" 9 "granulocytes: 18.9" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036696, HPA078030" Uncertain Supported "Plasma membrane,Primary cilium,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 55: Breast - Lactation" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 51: Secretory epithelial cells - Mixed function" 16 Cytosol "Plasma membrane, Primary cilium" "HPA036696: , HPA078030: " "unprognostic (1.76e-1)" "unprognostic (3.85e-1)" "unprognostic (3.94e-1)" "unprognostic (4.29e-2)" "unprognostic (3.36e-1)" "unprognostic (3.43e-2)" "unprognostic (1.53e-1)" "potential prognostic favorable (1.35e-4)" "unprognostic (1.79e-1)" "unprognostic (5.68e-2)" "potential prognostic favorable (3.86e-4)" "unprognostic (4.78e-3)" "unprognostic (5.79e-2)" "unprognostic (1.61e-2)" "unprognostic (1.62e-1)" "unprognostic (1.54e-1)" "unprognostic (3.82e-3)" "unprognostic (3.45e-2)" "unprognostic (7.48e-2)" "potential prognostic unfavorable (6.38e-4)" "unprognostic (1.45e-2)" "unprognostic (1.88e-3)" "unprognostic (3.70e-3)" "unprognostic (4.90e-2)" "unprognostic (3.22e-1)" "unprognostic (2.53e-1)" "unprognostic (1.15e-1)" "unprognostic (5.45e-2)" "unprognostic (1.16e-1)" "unprognostic (4.35e-3)" "unprognostic (1.09e-1)" MAP6 "FLJ41346, KIAA1878, MAP6-N, STOP" ENSG00000171533 "Microtubule associated protein 6" Q96JE9 11 75586918-75669038 "Predicted intracellular proteins" Transport Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 83.1;choroid plexus: 86.5;pituitary gland: 73.9;retina: 89.1" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 308.4;Corticotrophs: 90.6;Ependymal cells: 112.9;Fallopian tube ciliated cells: 90.3;Gonadotrophs: 92.1;Lactotrophs: 155.8;Other brain neurons: 94.8;Podocytes: 258.9;Respiratory ciliated cells: 122.6;Retinal bipolar cells: 139.7;Somatotrophs: 139.1;Thyrotrophs: 284.6" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 45.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Neuroblastoma: 32.0" "Liver - Hepatic stellate cells, Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Skeletal muscle - Fibroblasts, Skin - Eccrine sweat gland cells, Stomach - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015442, CAB022600, HPA039061, HPA039062" Enhanced NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 24: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 1 "CAB015442: , CAB022600: , HPA039061: , HPA039062: " "unprognostic (2.25e-1)" "unprognostic (6.56e-2)" "unprognostic (1.13e-1)" "unprognostic (7.41e-2)" "unprognostic (4.12e-2)" "unprognostic (8.98e-2)" "unprognostic (3.01e-2)" "unprognostic (1.80e-1)" "unprognostic (1.17e-2)" "unprognostic (3.47e-1)" "unprognostic (3.69e-2)" "unprognostic (7.14e-2)" "unprognostic (8.62e-3)" "unprognostic (2.40e-2)" "unprognostic (6.84e-2)" "potential prognostic unfavorable (3.35e-4)" "unprognostic (3.94e-1)" "unprognostic (2.20e-1)" "unprognostic (3.22e-1)" "potential prognostic favorable (9.33e-4)" "unprognostic (3.61e-2)" "unprognostic (7.54e-3)" "unprognostic (1.77e-1)" "unprognostic (7.63e-2)" "unprognostic (1.40e-1)" "unprognostic (2.28e-3)" "unprognostic (3.27e-2)" "unprognostic (1.90e-1)" "unprognostic (2.43e-1)" MAP6D1 "FLJ12748, SL21" ENSG00000180834 "MAP6 domain containing 1" Q9H9H5 3 183815922-183825594 "Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 120.4" "Cell type enriched" "Detected in some" 4 "Oligodendrocytes: 102.1" "Group enriched" "Detected in all" 4 "committed oligodendrocyte precursor: 50.6;oligodendrocyte: 129.3;upper rhombic lip: 40.0" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 14.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skeletal muscle - Skeletal myocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037991 Enhanced Supported Approved Cytosol NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 27: Breast cancer - Unknown function" "Cluster 80: Oligodendrocytes - Myelination" Cytosol "HPA037991: " "potential prognostic unfavorable (3.70e-4)" "unprognostic (3.89e-2)" "unprognostic (2.25e-1)" "unprognostic (1.80e-1)" "unprognostic (1.04e-2)" "unprognostic (3.75e-1)" "unprognostic (1.45e-1)" "unprognostic (1.58e-1)" "unprognostic (9.91e-2)" "unprognostic (4.77e-3)" "unprognostic (2.05e-1)" "unprognostic (3.11e-3)" "unprognostic (8.29e-2)" "unprognostic (2.22e-2)" "unprognostic (6.53e-2)" "unprognostic (4.69e-2)" "unprognostic (6.38e-2)" "potential prognostic unfavorable (1.10e-4)" "unprognostic (1.06e-1)" "unprognostic (3.10e-2)" "unprognostic (2.02e-1)" "unprognostic (6.85e-2)" "unprognostic (2.21e-2)" MAP7 E-MAP-115 ENSG00000135525 "Microtubule associated protein 7" Q14244 6 136342281-136550819 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 85.6" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 1845.9;Retinal bipolar cells: 1033.1" "Cell type enhanced" "Detected in all" "oligodendrocyte: 2683.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 12.2" "Group enriched" "Detected in many" 4 "dendritic cells: 5.7;granulocytes: 12.2;monocytes: 3.1" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029712, HPA029713" Enhanced Supported Microtubules,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 55 Cytosol Microtubules "HPA029712: , HPA029713: " "unprognostic (1.77e-1)" "unprognostic (1.66e-2)" "unprognostic (1.77e-2)" "potential prognostic unfavorable (1.14e-5)" "unprognostic (1.32e-3)" "unprognostic (1.34e-2)" "unprognostic (1.98e-1)" "unprognostic (1.30e-1)" "unprognostic (7.24e-2)" "unprognostic (7.26e-3)" "validated prognostic favorable (4.69e-12)" "validated prognostic favorable (4.68e-6)" "unprognostic (1.53e-1)" "potential prognostic favorable (3.09e-4)" "unprognostic (1.76e-1)" "unprognostic (2.66e-2)" "unprognostic (2.88e-1)" "unprognostic (2.06e-1)" "unprognostic (9.14e-2)" "unprognostic (4.05e-2)" "unprognostic (6.26e-2)" "unprognostic (7.83e-2)" "unprognostic (1.92e-2)" "unprognostic (4.20e-1)" "unprognostic (1.11e-2)" "unprognostic (2.62e-2)" "unprognostic (1.03e-1)" "unprognostic (6.13e-3)" "unprognostic (1.60e-1)" "unprognostic (3.30e-1)" "unprognostic (1.89e-1)" MAP7D1 "FLJ10350, FLJ39022, PARCC1, RPRC1" ENSG00000116871 "MAP7 domain containing 1" Q3KQU3 1 36155579-36180849 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 267.9" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 185.7;Esophageal suprabasal cells: 190.1;Ocular epithelial cells: 172.4;Suprabasal keratinocytes: 172.8;Syncytiotrophoblasts: 174.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Colon - Smooth muscle cells, Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028075 Approved NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 37: Non-specific - mRNA processing" "Cluster 100: Stratified epithelial cells - Barrier functions" 27 "HPA028075: " "unprognostic (1.51e-2)" "unprognostic (1.43e-1)" "unprognostic (1.21e-1)" "unprognostic (1.46e-3)" "unprognostic (5.32e-2)" "unprognostic (6.37e-3)" "unprognostic (3.53e-1)" "unprognostic (1.54e-2)" "unprognostic (3.26e-1)" "unprognostic (7.25e-3)" "unprognostic (2.87e-2)" "unprognostic (1.11e-1)" "unprognostic (9.88e-2)" "potential prognostic unfavorable (6.75e-4)" "unprognostic (2.98e-1)" "unprognostic (1.37e-1)" "unprognostic (5.62e-2)" "unprognostic (1.98e-2)" "unprognostic (2.89e-1)" "unprognostic (1.33e-2)" "unprognostic (1.44e-1)" "unprognostic (1.48e-1)" "unprognostic (3.40e-2)" "unprognostic (3.54e-2)" "unprognostic (2.09e-1)" "unprognostic (7.07e-2)" "unprognostic (1.50e-1)" "unprognostic (6.99e-2)" "unprognostic (2.51e-1)" "unprognostic (1.91e-2)" "unprognostic (2.72e-1)" MAP7D2 FLJ14503 ENSG00000184368 "MAP7 domain containing 2" Q96T17 X 20006713-20116907 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 29.9;epididymis: 34.4" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 68.4;Brain inhibitory neurons: 81.0;Cytotrophoblasts: 161.5;Differentiating spermatogonia: 208.4;Early primary spermatocytes: 111.8;Epididymal principal cells: 81.7;Foveolar cells: 120.3;Oocytes: 230.3;Other brain neurons: 71.6;Retinal amacrine cells: 67.2;Undifferentiated spermatogonia: 111.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "basophil: 3.0" "Lineage enriched" "Detected in single" 9 "granulocytes: 3.0" "Cancer enhanced" "Detected in many" "Kidney cancer: 20.4" "Colon - Colon enteroendocrine cells, Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Prostate - Prostate glandular cells, Skin - Outer root sheath cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051508, HPA059537" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 4 Nucleoplasm Cytosol "HPA051508: , HPA059537: " "potential prognostic unfavorable (8.33e-4)" "unprognostic (1.79e-1)" "unprognostic (8.42e-2)" "unprognostic (2.07e-1)" "unprognostic (1.60e-1)" "unprognostic (1.59e-1)" "unprognostic (2.84e-1)" "unprognostic (9.65e-3)" "unprognostic (1.95e-1)" "unprognostic (2.92e-2)" "unprognostic (1.09e-1)" "unprognostic (1.55e-1)" "unprognostic (2.03e-1)" "unprognostic (6.81e-3)" "unprognostic (3.47e-3)" "unprognostic (9.53e-2)" "unprognostic (2.05e-1)" "unprognostic (8.10e-2)" "unprognostic (6.42e-2)" "potential prognostic favorable (6.68e-4)" "unprognostic (6.88e-3)" "unprognostic (2.12e-1)" "unprognostic (1.68e-2)" "unprognostic (2.22e-1)" "unprognostic (1.20e-2)" "unprognostic (1.70e-1)" "unprognostic (4.27e-3)" MAP7D3 FLJ12649 ENSG00000129680 "MAP7 domain containing 3" Q8IWC1 X 136213220-136256482 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 128.0;Early spermatids: 191.3;Extravillous trophoblasts: 159.0;Late primary spermatocytes: 126.9;Late spermatids: 280.5;Oocytes: 142.8;Sertoli cells: 106.2;Undifferentiated spermatogonia: 100.2;Vascular smooth muscle cells: 112.0" "Cell type enhanced" "Detected in many" "vascular associated smooth muscle cell: 59.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Minor Salivary Gland - Endothelial cells" "Not detected" "Not detected" "HPA035598, HPA058101" Approved Uncertain "Nucleoplasm,Plasma membrane,Primary cilium,Centrosome,Basal body" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 36: Non-specific - mRNA processing" "Cluster 62: Smooth muscle cells - Muscle contraction" 16 "Plasma membrane, Centrosome" "Nucleoplasm, Primary cilium, Basal body" "HPA035598: , HPA058101: " "unprognostic (3.40e-1)" "unprognostic (1.69e-1)" "unprognostic (7.51e-3)" "unprognostic (5.53e-2)" "unprognostic (2.12e-3)" "unprognostic (1.77e-2)" "unprognostic (3.17e-2)" "unprognostic (3.18e-1)" "unprognostic (1.27e-2)" "unprognostic (7.59e-2)" "potential prognostic favorable (4.16e-4)" "unprognostic (4.81e-2)" "unprognostic (1.11e-1)" "potential prognostic unfavorable (2.36e-4)" "unprognostic (5.37e-2)" "unprognostic (1.00e-1)" "unprognostic (6.98e-2)" "unprognostic (1.74e-1)" "unprognostic (9.79e-2)" "unprognostic (1.20e-1)" "unprognostic (1.19e-1)" "unprognostic (3.23e-1)" "unprognostic (2.97e-2)" "unprognostic (6.89e-2)" "unprognostic (8.19e-2)" "unprognostic (3.48e-1)" "unprognostic (4.05e-2)" "unprognostic (4.42e-3)" "unprognostic (3.95e-1)" "unprognostic (1.03e-2)" "unprognostic (1.54e-2)" MAP9 "ASAP, FLJ21159" ENSG00000164114 "Microtubule associated protein 9" Q49MG5 4 155342658-155376970 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 31.9" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 132.3;Fallopian tube ciliated cells: 219.4;Respiratory ciliated cells: 237.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "prostate cancer: 32.1" "Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037864 Approved "Nuclear speckles,Primary cilium,Primary cilium transition zone,Centrosome" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 2 "Primary cilium, Primary cilium transition zone" "Nuclear speckles, Centrosome" "HPA037864: " "unprognostic (1.13e-1)" "unprognostic (1.40e-2)" "unprognostic (2.37e-1)" "unprognostic (7.46e-2)" "unprognostic (1.56e-1)" "unprognostic (5.94e-2)" "unprognostic (1.27e-2)" "unprognostic (6.70e-2)" "unprognostic (2.67e-1)" "unprognostic (3.03e-2)" "unprognostic (1.97e-1)" "unprognostic (1.45e-1)" "unprognostic (4.83e-2)" "unprognostic (9.80e-2)" "unprognostic (8.45e-3)" "unprognostic (1.80e-1)" "unprognostic (3.62e-1)" "unprognostic (1.35e-3)" "unprognostic (1.30e-1)" "unprognostic (4.67e-2)" "unprognostic (1.97e-1)" "unprognostic (4.67e-1)" "unprognostic (6.58e-2)" "unprognostic (4.03e-2)" "unprognostic (4.68e-2)" "unprognostic (1.47e-1)" "unprognostic (3.79e-2)" "unprognostic (1.27e-1)" MAPK1 "ERK, ERK2, MAPK2, p41mapk, PRKM1, PRKM2" ENSG00000100030 "Mitogen-activated protein kinase 1" P28482 22 21759657-21867680 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "DNA-binding, Kinase, Repressor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Mast cells: 608.3;Neutrophil progenitors: 707.3;Neutrophils: 1044.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Smooth muscle cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003995, CAB004229, HPA005700, HPA030069, CAB079932, CAB079933" Enhanced Supported "Nucleoplasm,Microtubules,Primary cilium,Primary cilium tip,Basal body,Cytosol" NA NA 270000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 73: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 193 Nucleoplasm "Microtubules, Primary cilium, Primary cilium tip, Basal body, Cytosol" "CAB004229: , CAB079932: , CAB079933: , HPA003995: , HPA005700: , HPA030069: " "unprognostic (6.01e-2)" "unprognostic (4.30e-2)" "unprognostic (1.37e-1)" "unprognostic (1.33e-1)" "unprognostic (1.51e-2)" "unprognostic (2.84e-1)" "unprognostic (2.38e-2)" "unprognostic (1.71e-1)" "unprognostic (1.62e-1)" "unprognostic (1.27e-1)" "potential prognostic favorable (1.27e-6)" "unprognostic (4.91e-3)" "unprognostic (1.33e-1)" "unprognostic (1.24e-3)" "potential prognostic unfavorable (5.21e-4)" "unprognostic (1.52e-1)" "unprognostic (9.62e-2)" "unprognostic (9.27e-2)" "unprognostic (8.98e-3)" "unprognostic (1.70e-1)" "unprognostic (9.52e-3)" "unprognostic (9.83e-3)" "unprognostic (2.45e-1)" "unprognostic (1.56e-1)" "unprognostic (1.40e-2)" "unprognostic (9.44e-2)" "unprognostic (5.94e-2)" "unprognostic (1.43e-1)" "unprognostic (2.33e-1)" "unprognostic (7.79e-2)" "unprognostic (2.30e-1)" MAPK10 "JNK3, p493F12, p54bSAPK, PRKM10" ENSG00000109339 "Mitogen-activated protein kinase 10" P53779 4 85990007-86594625 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 73.7" "Cell type enhanced" "Detected in many" "Astrocytes: 1652.4;Bergmann glia: 1620.1;Choroid plexus epithelial cells: 2097.0;Corticotrophs: 1206.0;Ependymal cells: 2326.9;Pituicytes/FSCs: 1383.6;Respiratory ciliated cells: 1789.2;Somatotrophs: 1334.5;Thyrotrophs: 1412.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast), Liver - Hepatic stellate cells, Lung - Respiratory ciliated cells, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022625, HPA068627, HPA071800" Approved Supported Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 73: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 26 Nucleoplasm "CAB022625: , HPA068627: , HPA071800: " "unprognostic (1.08e-1)" "potential prognostic unfavorable (1.58e-4)" "unprognostic (2.94e-1)" "unprognostic (9.78e-2)" "unprognostic (3.74e-2)" "unprognostic (5.04e-2)" "unprognostic (1.21e-2)" "potential prognostic favorable (3.13e-4)" "unprognostic (2.31e-1)" "unprognostic (5.71e-2)" "validated prognostic favorable (4.39e-6)" "validated prognostic favorable (2.14e-5)" "unprognostic (2.73e-2)" "unprognostic (1.61e-3)" "unprognostic (5.42e-2)" "unprognostic (8.39e-3)" "unprognostic (1.73e-1)" "unprognostic (9.86e-2)" "unprognostic (1.31e-1)" "unprognostic (3.28e-2)" "unprognostic (2.69e-2)" "unprognostic (1.42e-3)" "unprognostic (1.85e-1)" "unprognostic (3.94e-2)" "unprognostic (3.95e-2)" "potential prognostic favorable (7.55e-4)" "unprognostic (1.13e-1)" "unprognostic (2.79e-2)" "unprognostic (1.48e-1)" "unprognostic (6.84e-2)" "unprognostic (4.02e-2)" MAPK11 "p38-2, p38Beta, PRKM11, SAPK2" ENSG00000185386 "Mitogen-activated protein kinase 11" Q15759 22 50263713-50270767 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 62.6" "Cell type enhanced" "Detected in many" "Adipocytes: 13.2;Astrocytes: 27.6;Bergmann glia: 14.3;Brain excitatory neurons: 15.9;Brain inhibitory neurons: 13.6;Late spermatids: 18.2;Vascular endothelial cells: 25.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Endothelial cells, Colon - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Pancreas - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012961, HPA045069, HPA073133" Approved Approved Cytosol NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 30 Cytosol "CAB012961: , HPA045069: , HPA073133: " "unprognostic (1.09e-2)" "unprognostic (4.89e-2)" "unprognostic (7.91e-2)" "unprognostic (1.74e-2)" "unprognostic (2.71e-2)" "unprognostic (4.50e-2)" "unprognostic (1.37e-2)" "unprognostic (2.53e-2)" "unprognostic (4.00e-3)" "unprognostic (2.68e-2)" "unprognostic (3.22e-1)" "unprognostic (2.14e-2)" "unprognostic (9.00e-2)" "unprognostic (2.07e-2)" "unprognostic (1.18e-3)" "unprognostic (2.61e-2)" "unprognostic (1.33e-1)" "unprognostic (3.63e-1)" "unprognostic (6.64e-2)" "unprognostic (2.07e-1)" "unprognostic (1.22e-1)" "unprognostic (6.43e-3)" "potential prognostic unfavorable (3.06e-4)" "unprognostic (1.14e-1)" "unprognostic (4.39e-2)" "unprognostic (2.14e-2)" "unprognostic (3.22e-1)" "unprognostic (3.24e-1)" "unprognostic (5.09e-2)" "unprognostic (2.63e-1)" "unprognostic (9.50e-2)" MAPK12 "ERK6, p38gamma, PRKM12, SAPK-3, SAPK3" ENSG00000188130 "Mitogen-activated protein kinase 12" P53778 22 50245450-50261716 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "skeletal muscle: 280.4;tongue: 112.9" "Cell type enhanced" "Detected in many" "Astrocytes: 31.8;Bergmann glia: 16.3;Corticotrophs: 17.3;Epididymal principal cells: 33.5;Gonadotrophs: 26.2;Megakaryocyte progenitors: 17.3;Megakaryocytes: 18.5;Myonuclei: 25.4;Thymic myoid cells: 27.2;Vascular endothelial cells: 19.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Skin - Endothelial cells" "Region enhanced" "Detected in all" "cerebellum: 31.6" "Low region specificity" "Detected in all" "CAB025483, HPA054562" Enhanced Approved "Nuclear speckles,Cytosol" NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" 19 "Nuclear speckles" Cytosol "CAB025483: , HPA054562: " "unprognostic (8.62e-2)" "unprognostic (2.92e-2)" "unprognostic (2.62e-2)" "unprognostic (9.39e-2)" "unprognostic (1.23e-2)" "unprognostic (1.68e-2)" "unprognostic (8.25e-2)" "unprognostic (2.80e-3)" "unprognostic (5.07e-3)" "unprognostic (4.20e-3)" "unprognostic (8.04e-2)" "unprognostic (7.32e-2)" "unprognostic (1.08e-1)" "unprognostic (7.93e-3)" "unprognostic (3.52e-2)" "unprognostic (1.53e-3)" "unprognostic (5.43e-2)" "unprognostic (1.28e-1)" "unprognostic (1.45e-1)" "unprognostic (2.53e-2)" "unprognostic (1.98e-1)" "unprognostic (1.23e-1)" "unprognostic (1.47e-3)" "unprognostic (2.55e-1)" "unprognostic (5.92e-3)" "unprognostic (7.77e-2)" "unprognostic (2.51e-1)" "unprognostic (8.00e-2)" "unprognostic (2.68e-1)" "unprognostic (1.24e-2)" "unprognostic (1.53e-1)" MAPK13 "p38delta, PRKM13, SAPK4" ENSG00000156711 "Mitogen-activated protein kinase 13" O15264 6 36127809-36144524 "Enzymes, Predicted intracellular proteins" "Cell cycle, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast lactating cells: 315.8;Colonocytes: 139.1;Enterocytes: 171.9;Esophageal apical cells: 474.9;Esophageal basal cells: 159.7;Esophageal suprabasal cells: 262.2;Late primary spermatocytes: 200.1;Late spermatids: 457.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Skin - Keratinocyte (other), Spleen - Neutrophils_2, Testis - Early spermatids" "Low region specificity" "Detected in single" "Region enriched" "Detected in all" 14 "cerebellum: 41.0" "HPA007667, CAB025854" Enhanced Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 53: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 10 "Nucleoplasm, Nucleoli, Nucleoli rim, Cytosol" "CAB025854: , HPA007667: " "unprognostic (9.81e-2)" "unprognostic (5.49e-3)" "unprognostic (9.02e-2)" "unprognostic (5.41e-2)" "unprognostic (3.52e-1)" "unprognostic (2.55e-1)" "unprognostic (5.00e-3)" "unprognostic (9.60e-3)" "unprognostic (6.52e-2)" "unprognostic (2.08e-2)" "potential prognostic favorable (1.17e-4)" "unprognostic (1.43e-2)" "unprognostic (8.37e-2)" "unprognostic (3.98e-3)" "unprognostic (1.25e-2)" "unprognostic (4.22e-2)" "unprognostic (8.11e-2)" "unprognostic (1.25e-1)" "unprognostic (2.52e-2)" "unprognostic (1.39e-2)" "unprognostic (1.48e-1)" "unprognostic (8.05e-2)" "unprognostic (9.72e-3)" "unprognostic (2.25e-1)" "unprognostic (6.18e-3)" "unprognostic (2.20e-2)" "unprognostic (1.21e-1)" "unprognostic (8.24e-2)" "unprognostic (3.83e-1)" "unprognostic (2.24e-1)" "unprognostic (1.37e-1)" MAPK14 "CSBP1, CSBP2, CSPB1, Mxi2, p38, PRKM14, PRKM15" ENSG00000112062 "Mitogen-activated protein kinase 14" Q16539 6 36027782-36111236 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Apoptosis, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Monocyte progenitors: 731.2;Neutrophil progenitors: 1492.2;Neutrophils: 2779.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 78.0;neutrophil: 25.8" "Lineage enriched" "Detected in all" 7 "granulocytes: 78.0" "Low cancer specificity" "Detected in all" "Lung - Neutrophils_2, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010285, CAB040578, HPA051825" Approved Supported "Nuclear speckles,Cytosol" NA NA 650000 "Cluster 41: Basophils - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 31: Non-specific - Transcription" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 121 "Nuclear speckles" Cytosol "CAB010285: , CAB040578: , HPA051825: " "unprognostic (2.70e-2)" "unprognostic (1.33e-1)" "unprognostic (6.38e-2)" "unprognostic (8.86e-3)" "unprognostic (6.92e-2)" "unprognostic (2.51e-3)" "unprognostic (3.78e-1)" "unprognostic (1.62e-1)" "unprognostic (9.50e-2)" "potential prognostic unfavorable (2.90e-4)" "potential prognostic favorable (7.79e-5)" "unprognostic (1.21e-2)" "unprognostic (1.35e-1)" "unprognostic (6.59e-2)" "unprognostic (5.56e-2)" "unprognostic (1.35e-1)" "unprognostic (6.04e-2)" "unprognostic (9.57e-2)" "unprognostic (6.94e-2)" "unprognostic (5.39e-2)" "unprognostic (2.40e-3)" "unprognostic (1.72e-2)" "unprognostic (3.96e-3)" "unprognostic (6.07e-2)" "unprognostic (1.97e-3)" "unprognostic (2.20e-1)" "unprognostic (5.49e-3)" "unprognostic (6.84e-3)" "unprognostic (2.00e-1)" "unprognostic (1.33e-1)" "unprognostic (4.02e-1)" MAPK15 "ERK7, ERK8" ENSG00000181085 "Mitogen-activated protein kinase 15" Q8TD08 8 143716340-143722458 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 70.7;fallopian tube: 36.1" "Group enriched" "Detected in some" 6 "Choroid plexus epithelial cells: 105.6;Ependymal cells: 134.2" "Group enriched" "Detected in many" 13 "choroid plexus epithelial cell: 99.7;ependymal cell: 139.5" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 20.0;Uterine Corpus Endometrial Carcinoma (TCGA): 19.3" "Region enhanced" "Detected in all" "choroid plexus: 111.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Colon - Enteric glia cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA002704 Approved "Nucleoplasm,Vesicles,Cell Junctions,Cytosol" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 27: Breast cancer - Unknown function" "Cluster 34: Ciliated cells - Cilia assembly & function" 9 "Nucleoplasm, Cytosol" "Vesicles, Cell Junctions" "HPA002704: " "unprognostic (4.07e-2)" "unprognostic (1.48e-1)" "unprognostic (3.14e-1)" "unprognostic (4.25e-1)" "unprognostic (4.15e-2)" "unprognostic (4.44e-2)" "unprognostic (1.88e-1)" "unprognostic (2.61e-1)" "potential prognostic unfavorable (3.25e-5)" "unprognostic (2.64e-2)" "unprognostic (7.06e-3)" "unprognostic (5.84e-2)" "unprognostic (4.54e-2)" "unprognostic (2.65e-1)" "unprognostic (2.44e-1)" "unprognostic (4.84e-2)" "unprognostic (2.61e-1)" "unprognostic (1.30e-2)" "unprognostic (2.17e-1)" "potential prognostic unfavorable (3.73e-4)" "unprognostic (1.13e-1)" "unprognostic (5.37e-2)" "unprognostic (2.60e-2)" "unprognostic (2.37e-1)" "unprognostic (8.07e-2)" "unprognostic (2.22e-1)" MAPK1IP1L C14orf32 ENSG00000168175 "Mitogen-activated protein kinase 1 interacting protein 1 like" Q8NDC0 14 55051647-55070194 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034506 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 15: Bone marrow - Innate immune response" "Cluster 21: Non-specific - Metabolism" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 9: T-cells - Adaptive immunity: Regulation" 24 "Nucleoplasm, Cytosol" "HPA034506: " "unprognostic (1.92e-1)" "unprognostic (1.94e-1)" "unprognostic (2.34e-1)" "unprognostic (2.15e-1)" "unprognostic (7.13e-2)" "unprognostic (1.70e-1)" "unprognostic (1.32e-1)" "unprognostic (3.70e-1)" "unprognostic (1.26e-1)" "unprognostic (1.57e-3)" "potential prognostic favorable (3.40e-5)" "unprognostic (9.40e-3)" "unprognostic (7.01e-3)" "potential prognostic unfavorable (4.13e-4)" "unprognostic (5.82e-2)" "potential prognostic unfavorable (8.09e-5)" "unprognostic (4.27e-1)" "unprognostic (1.84e-1)" "unprognostic (5.73e-3)" "unprognostic (8.13e-2)" "unprognostic (2.23e-1)" "unprognostic (3.39e-1)" "unprognostic (1.33e-3)" "unprognostic (1.70e-1)" "unprognostic (2.46e-1)" "unprognostic (1.04e-2)" "unprognostic (1.44e-1)" "unprognostic (3.51e-1)" "unprognostic (2.29e-1)" "unprognostic (3.78e-2)" "unprognostic (2.96e-1)" MAPK3 "ERK1, p44erk1, p44mapk, PRKM3" ENSG00000102882 "Mitogen-activated protein kinase 3" P27361 16 30114105-30123506 "Cancer-related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Cell cycle, Host-virus interaction" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 268.7;Early spermatids: 326.3;Enterocytes: 226.1;Esophageal apical cells: 543.4;Extravillous trophoblasts: 188.0;Foveolar cells: 172.9;Goblet cells: 190.0;Late spermatids: 229.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "eosinophil: 49.2;neutrophil: 21.6" "Lineage enriched" "Detected in all" 7 "granulocytes: 49.2" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002683, HPA003995, HPA005700, HPA030069" Approved Supported "Nucleoplasm,Microtubules,Primary cilium,Primary cilium tip,Basal body,Cytosol" NA NA 92000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 110 Nucleoplasm "Microtubules, Primary cilium, Primary cilium tip, Basal body, Cytosol" "CAB002683: , HPA003995: , HPA005700: , HPA030069: " "unprognostic (1.23e-1)" "unprognostic (3.99e-2)" "unprognostic (1.29e-1)" "unprognostic (2.90e-1)" "unprognostic (9.14e-2)" "unprognostic (2.28e-1)" "unprognostic (1.90e-1)" "unprognostic (3.04e-1)" "unprognostic (2.41e-1)" "unprognostic (7.32e-2)" "potential prognostic favorable (4.11e-7)" "unprognostic (3.91e-3)" "unprognostic (2.61e-2)" "validated prognostic unfavorable (7.45e-5)" "validated prognostic unfavorable (3.39e-4)" "unprognostic (4.37e-2)" "unprognostic (4.88e-2)" "unprognostic (4.41e-3)" "unprognostic (4.10e-2)" "unprognostic (9.34e-2)" "unprognostic (5.80e-2)" "unprognostic (1.06e-2)" "unprognostic (5.11e-2)" "unprognostic (2.41e-1)" "unprognostic (1.64e-1)" "unprognostic (1.92e-2)" "unprognostic (1.28e-1)" "unprognostic (1.72e-1)" "unprognostic (2.78e-1)" "unprognostic (9.64e-2)" "unprognostic (9.83e-2)" MAPK4 "Erk3-related, Erk4, PRKM4" ENSG00000141639 "Mitogen-activated protein kinase 4" P31152 18 50560087-50731826 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 72.2;parathyroid gland: 47.9" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 215.7;Astrocytes: 388.3;Bergmann glia: 489.0;Brain inhibitory neurons: 190.1;Cardiomyocytes: 189.3;Choroid plexus epithelial cells: 533.1;Ependymal cells: 229.4;Müller glia: 345.3;Pituicytes/FSCs: 1914.2" "Cell type enhanced" "Detected in many" "astrocyte: 509.5;Bergmann glia: 522.4" "Cancer enriched" "Detected in many" 4 "Glioblastoma Multiforme (TCGA): 38.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 18.0;Rhabdoid: 9.6" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Adrenal gland - Adrenal cortex cells, Kidney - Ascending Loop of Henle cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007461 Approved "Nucleoplasm,Golgi apparatus,Midbody,Cytosol" Yes NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 19: Astrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 23 "Nucleoplasm, Golgi apparatus" "Midbody, Cytosol" "HPA007461: " "unprognostic (1.22e-1)" "unprognostic (5.02e-2)" "unprognostic (1.83e-1)" "unprognostic (1.88e-1)" "unprognostic (1.50e-1)" "unprognostic (1.89e-1)" "unprognostic (5.56e-2)" "unprognostic (1.76e-3)" "unprognostic (1.40e-2)" "unprognostic (3.80e-2)" "potential prognostic favorable (6.32e-4)" "unprognostic (8.22e-2)" "unprognostic (4.93e-3)" "unprognostic (1.07e-1)" "unprognostic (1.82e-1)" "potential prognostic unfavorable (4.54e-4)" "unprognostic (6.21e-3)" "unprognostic (8.78e-3)" MAPK6 "ERK3, HsT17250, p97MAPK, PRKM6" ENSG00000069956 "Mitogen-activated protein kinase 6" Q16659 15 51952106-52067375 "Enzymes, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 401.0;Mast cells: 378.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005184, HPA030262, HPA047825" Approved Supported Approved "Microtubules,Primary cilium,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 37 Cytosol "Microtubules, Primary cilium" "CAB005184: , HPA030262: , HPA047825: " "unprognostic (1.07e-1)" "unprognostic (3.05e-2)" "unprognostic (9.56e-2)" "unprognostic (1.61e-2)" "unprognostic (3.95e-2)" "unprognostic (6.03e-2)" "unprognostic (3.66e-1)" "unprognostic (4.14e-1)" "unprognostic (7.79e-2)" "unprognostic (1.55e-2)" "unprognostic (5.65e-2)" "unprognostic (1.55e-1)" "unprognostic (5.81e-2)" "unprognostic (4.09e-2)" "unprognostic (3.00e-2)" "potential prognostic unfavorable (1.33e-4)" "unprognostic (1.82e-3)" "unprognostic (4.06e-1)" "unprognostic (1.84e-1)" "unprognostic (3.90e-1)" "unprognostic (4.82e-2)" "unprognostic (5.92e-3)" "unprognostic (1.43e-2)" "unprognostic (1.50e-1)" "unprognostic (7.25e-2)" "unprognostic (4.70e-2)" "unprognostic (7.60e-2)" "unprognostic (1.67e-1)" "unprognostic (2.20e-1)" "unprognostic (1.34e-2)" "unprognostic (2.17e-1)" MAPK7 "BMK1, ERK5, PRKM7" ENSG00000166484 "Mitogen-activated protein kinase 7" Q13164 17 19377721-19383544 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Differentiation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 27.1;Esophageal apical cells: 77.4;Esophageal suprabasal cells: 27.4;Late primary spermatocytes: 28.9;Lymphatic endothelial cells: 26.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "testis cancer: 49.5" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018561, HPA031031" Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 44: Non-specific - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 39 "Nucleoplasm, Cytosol" "CAB018561: , HPA031031: " "unprognostic (9.31e-2)" "unprognostic (6.71e-2)" "unprognostic (8.92e-2)" "unprognostic (6.25e-3)" "unprognostic (2.89e-1)" "unprognostic (3.86e-2)" "unprognostic (9.54e-2)" "unprognostic (2.88e-1)" "unprognostic (2.42e-3)" "unprognostic (2.05e-3)" "unprognostic (1.79e-3)" "unprognostic (3.70e-2)" "unprognostic (1.13e-1)" "potential prognostic unfavorable (9.21e-5)" "unprognostic (1.36e-2)" "unprognostic (1.19e-2)" "unprognostic (2.21e-2)" "unprognostic (2.46e-2)" "unprognostic (2.95e-1)" "unprognostic (3.63e-2)" "unprognostic (1.78e-1)" "unprognostic (1.44e-2)" "unprognostic (2.80e-3)" "unprognostic (1.68e-2)" "unprognostic (2.05e-1)" "unprognostic (1.24e-1)" "unprognostic (7.05e-2)" "unprognostic (3.74e-2)" "unprognostic (4.85e-1)" "unprognostic (1.43e-2)" "unprognostic (1.47e-1)" MAPK8 "JNK, JNK1, PRKM8, SAPK1" ENSG00000107643 "Mitogen-activated protein kinase 8" P45983 10 48306639-48439360 "Cancer-related genes, Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Spleen - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004463, CAB069396, HPA071800" Approved Supported Nucleoplasm NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 27: Cerebellum - Synaptic function" "Cluster 16: Non-specific - Transcription" "Cluster 59: Leukemia - T-cell receptor" "Cluster 51: Secretory epithelial cells - Mixed function" 91 Nucleoplasm "CAB004463: , CAB069396: , HPA071800: " "unprognostic (6.09e-2)" "unprognostic (5.38e-2)" "unprognostic (4.71e-2)" "unprognostic (1.06e-1)" "unprognostic (6.09e-2)" "unprognostic (4.38e-2)" "unprognostic (2.60e-2)" "potential prognostic favorable (7.27e-5)" "unprognostic (1.51e-1)" "unprognostic (1.16e-1)" "potential prognostic favorable (1.72e-6)" "unprognostic (1.22e-3)" "unprognostic (1.98e-2)" "unprognostic (2.44e-3)" "unprognostic (4.73e-2)" "unprognostic (3.42e-2)" "unprognostic (1.74e-1)" "unprognostic (3.32e-2)" "unprognostic (3.39e-1)" "unprognostic (2.50e-1)" "potential prognostic unfavorable (1.23e-4)" "unprognostic (5.79e-2)" "potential prognostic unfavorable (4.29e-5)" "unprognostic (1.11e-1)" "unprognostic (3.06e-2)" "unprognostic (3.59e-2)" "unprognostic (2.37e-2)" "unprognostic (3.59e-2)" "unprognostic (1.82e-1)" "unprognostic (3.47e-2)" "unprognostic (9.92e-2)" MAPK8IP1 "IB1, JIP-1, JIP1, PRKM8IP" ENSG00000121653 "Mitogen-activated protein kinase 8 interacting protein 1" Q9UQF2 11 45885651-45906465 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "brain: 255.8;pituitary gland: 113.0" "Cell type enhanced" "Detected in many" "Corticotrophs: 49.6;Gonadotrophs: 64.0;Late spermatids: 43.2;Oligodendrocytes: 76.1;Pancreatic islet cells: 38.5;Retinal horizontal cells: 52.1;Somatotrophs: 38.7" "Cell type enhanced" "Detected in all" "oligodendrocyte: 102.4" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 110.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enteroendocrine cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058921, HPA070332, HPA079657" Approved Enhanced "Plasma membrane" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 80: Oligodendrocytes - Myelination" 32 "Plasma membrane" "HPA058921: , HPA070332: , HPA079657: " "unprognostic (4.55e-2)" "unprognostic (1.91e-1)" "unprognostic (2.62e-2)" "unprognostic (3.36e-2)" "unprognostic (1.49e-1)" "unprognostic (3.97e-3)" "unprognostic (8.00e-2)" "unprognostic (3.19e-3)" "unprognostic (2.90e-1)" "unprognostic (6.06e-2)" "potential prognostic favorable (6.59e-8)" "unprognostic (9.65e-2)" "unprognostic (9.76e-3)" "unprognostic (1.53e-2)" "unprognostic (4.54e-2)" "unprognostic (7.82e-3)" "unprognostic (3.60e-1)" "unprognostic (1.47e-1)" "unprognostic (3.04e-1)" "unprognostic (1.31e-1)" "unprognostic (7.08e-2)" "unprognostic (6.75e-3)" "unprognostic (4.92e-2)" "unprognostic (4.56e-2)" "unprognostic (2.68e-1)" "unprognostic (1.23e-2)" "unprognostic (2.14e-2)" "unprognostic (5.93e-2)" "unprognostic (2.75e-1)" "unprognostic (1.35e-2)" "unprognostic (1.52e-1)" MAPK8IP2 "IB2, JIP2, PRKM8IPL" ENSG00000008735 "Mitogen-activated protein kinase 8 interacting protein 2" Q13387 22 50600793-50613981 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 103.2" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 39.8;Brain inhibitory neurons: 31.3;Corticotrophs: 40.7;Gonadotrophs: 22.8;Lactotrophs: 19.2;Neuroendocrine cells: 19.2;Other brain neurons: 34.0;Pancreatic islet cells: 42.0;Retinal amacrine cells: 52.0;Retinal bipolar cells: 29.4;Retinal ganglion cells: 23.2;Retinal horizontal cells: 50.1;Somatotrophs: 18.5;Thyrotrophs: 23.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 26.1" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells, Stomach - Gastric enteroendocrine cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034780 Uncertain NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 24: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 32 "HPA034780: " "unprognostic (4.95e-2)" "unprognostic (1.75e-1)" "unprognostic (6.40e-2)" "unprognostic (1.60e-2)" "unprognostic (7.23e-2)" "unprognostic (1.58e-1)" "unprognostic (1.52e-1)" "unprognostic (1.87e-2)" "unprognostic (7.01e-2)" "unprognostic (5.91e-2)" "potential prognostic unfavorable (2.01e-4)" "unprognostic (8.46e-2)" "unprognostic (6.18e-2)" "unprognostic (3.40e-1)" "unprognostic (2.82e-2)" "unprognostic (2.48e-1)" "unprognostic (3.49e-3)" "unprognostic (6.06e-3)" "unprognostic (1.23e-1)" "potential prognostic unfavorable (6.81e-4)" "unprognostic (1.40e-1)" "unprognostic (1.22e-3)" "unprognostic (1.94e-3)" "unprognostic (6.95e-2)" "unprognostic (2.07e-1)" MAPK8IP3 "JIP3, JSAP1, KIAA1066, syd" ENSG00000138834 "Mitogen-activated protein kinase 8 interacting protein 3" Q9UPT6 16 1706166-1770351 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 184.1" "Cell type enhanced" "Detected in many" "Retinal ganglion cells: 239.5;Retinal horizontal cells: 228.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 3.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005580, HPA041785, HPA069311" Approved Approved "Vesicles,Cytokinetic bridge,Centrosome,Cytosol" Yes NA "Cluster 19: Eosinophils - Unknown function" "Cluster 71: Cerebellum - Nervous system development" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 54: Non-specific - Transcription" "Cluster 51: Secretory epithelial cells - Mixed function" 24 Vesicles "Cytokinetic bridge, Centrosome, Cytosol" "CAB005580: , HPA041785: , HPA069311: " "unprognostic (4.99e-2)" "unprognostic (5.45e-1)" "unprognostic (7.62e-2)" "unprognostic (5.62e-2)" "unprognostic (7.16e-2)" "unprognostic (2.69e-2)" "unprognostic (3.39e-1)" "unprognostic (5.50e-3)" "unprognostic (1.27e-2)" "unprognostic (2.48e-1)" "potential prognostic unfavorable (2.27e-6)" "unprognostic (8.05e-2)" "unprognostic (4.06e-2)" "unprognostic (2.98e-2)" "unprognostic (4.82e-1)" "unprognostic (4.41e-2)" "unprognostic (1.02e-1)" "unprognostic (4.07e-2)" "unprognostic (2.87e-3)" "unprognostic (2.42e-1)" "unprognostic (4.19e-2)" "unprognostic (1.20e-2)" "potential prognostic unfavorable (2.35e-4)" "unprognostic (1.73e-2)" "unprognostic (2.18e-1)" "unprognostic (1.64e-2)" "unprognostic (5.40e-2)" "unprognostic (3.49e-1)" "unprognostic (3.91e-1)" "unprognostic (2.22e-1)" "unprognostic (9.54e-2)" MAPK9 "JNK2, p54a, PRKM9, SAPK" ENSG00000050748 "Mitogen-activated protein kinase 9" P45984 5 180233143-180292099 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "basophil: 16.3" "Lineage enriched" "Detected in all" 6 "granulocytes: 16.3" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008910, HPA072462" Enhanced Approved "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 27: Cerebellum - Synaptic function" "Cluster 37: Neurons - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 109: Neurons - Neuronal signaling" 100 "Plasma membrane, Cytosol" "Nuclear speckles" "CAB008910: , HPA072462: " "unprognostic (2.42e-2)" "unprognostic (1.38e-2)" "unprognostic (3.96e-2)" "unprognostic (3.46e-2)" "unprognostic (1.95e-2)" "unprognostic (1.02e-1)" "unprognostic (1.57e-1)" "unprognostic (4.17e-2)" "unprognostic (8.28e-3)" "unprognostic (4.09e-3)" "potential prognostic favorable (1.53e-7)" "unprognostic (1.00e-2)" "unprognostic (1.19e-1)" "unprognostic (2.88e-2)" "unprognostic (7.76e-2)" "unprognostic (1.89e-1)" "unprognostic (1.73e-1)" "unprognostic (1.55e-3)" "unprognostic (2.96e-1)" "unprognostic (1.29e-1)" "potential prognostic unfavorable (3.83e-4)" "unprognostic (4.23e-2)" "unprognostic (9.76e-3)" "unprognostic (2.62e-1)" "unprognostic (3.54e-2)" "unprognostic (1.79e-1)" "unprognostic (2.61e-1)" "unprognostic (2.66e-1)" "unprognostic (1.89e-1)" "unprognostic (1.50e-3)" "unprognostic (2.11e-1)" MAPKAP1 "MGC2745, MIP1, SIN1" ENSG00000119487 "MAPK associated protein 1" Q9BPZ7 9 125437393-125707234 "Predicted intracellular proteins" "Stress response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029091, HPA029092" Supported Approved "Nucleoplasm,Primary cilium,Cytosol" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Transcription" 29 Nucleoplasm "Primary cilium, Cytosol" "HPA029091: , HPA029092: " "unprognostic (7.46e-2)" "unprognostic (1.60e-2)" "unprognostic (2.35e-2)" "unprognostic (5.98e-2)" "unprognostic (2.98e-1)" "unprognostic (8.50e-3)" "unprognostic (3.80e-1)" "unprognostic (8.39e-2)" "unprognostic (1.13e-1)" "unprognostic (1.73e-2)" "potential prognostic favorable (6.63e-4)" "unprognostic (4.04e-2)" "unprognostic (1.44e-2)" "potential prognostic unfavorable (5.82e-4)" "unprognostic (1.71e-3)" "unprognostic (5.30e-3)" "unprognostic (2.01e-2)" "unprognostic (2.06e-1)" "unprognostic (4.32e-3)" "unprognostic (2.38e-2)" "unprognostic (1.81e-1)" "unprognostic (3.15e-2)" "unprognostic (9.91e-2)" "unprognostic (3.40e-1)" "unprognostic (3.32e-1)" "unprognostic (5.15e-2)" "unprognostic (3.73e-1)" "unprognostic (2.17e-2)" "unprognostic (2.77e-1)" "unprognostic (3.26e-1)" "unprognostic (3.32e-1)" MAPKAPK2 MK2 ENSG00000162889 "MAPK activated protein kinase 2" P49137 1 206684905-206734281 "Cancer-related genes, Enzymes, Predicted membrane proteins" "DNA damage" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 1055.9;pDCs: 629.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "plasmacytoid DC: 21.9" "Lineage enriched" "Detected in all" 6 "dendritic cells: 21.9" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010297, HPA045556, HPA063708, HPA064435" Approved Supported "Nucleoplasm,Centrosome,Basal body" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 44: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 52 Nucleoplasm "Centrosome, Basal body" "CAB010297: , HPA045556: , HPA063708: , HPA064435: " "unprognostic (2.33e-1)" "unprognostic (2.07e-1)" "unprognostic (3.19e-1)" "unprognostic (2.23e-3)" "unprognostic (2.70e-1)" "unprognostic (1.03e-2)" "unprognostic (1.66e-2)" "unprognostic (9.40e-2)" "unprognostic (3.21e-2)" "unprognostic (1.73e-1)" "unprognostic (1.39e-2)" "unprognostic (9.57e-2)" "potential prognostic unfavorable (2.31e-5)" "unprognostic (2.36e-3)" "unprognostic (2.71e-2)" "unprognostic (4.83e-2)" "unprognostic (1.61e-3)" "unprognostic (1.04e-1)" "unprognostic (8.27e-2)" "unprognostic (7.98e-2)" "unprognostic (6.52e-2)" "unprognostic (6.90e-2)" "unprognostic (6.62e-2)" "unprognostic (5.66e-2)" "unprognostic (4.80e-2)" "unprognostic (6.22e-2)" "unprognostic (1.77e-1)" "unprognostic (4.36e-1)" "unprognostic (2.15e-1)" "unprognostic (2.18e-1)" "unprognostic (4.60e-1)" MAPKAPK3 "3pK, MAPKAP3, MK-3, MK3" ENSG00000114738 "MAPK activated protein kinase 3" Q16644 3 50611520-50649291 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 241.8;skeletal muscle: 213.3;tongue: 265.2" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 174.8;Esophageal suprabasal cells: 122.7;Hofbauer cells: 128.4;Late spermatids: 170.3" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 34.6;leukocyte: 35.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "dendritic cells: 142.9;granulocytes: 126.6;monocytes: 343.2" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Heart muscle - Cardiomyocytes, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058275 Supported Nucleoplasm NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 44: Non-specific - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 19 Nucleoplasm "HPA058275: " "unprognostic (2.91e-2)" "unprognostic (2.70e-2)" "unprognostic (9.61e-2)" "unprognostic (2.98e-2)" "unprognostic (1.08e-2)" "unprognostic (1.14e-1)" "unprognostic (2.28e-1)" "unprognostic (1.27e-1)" "unprognostic (6.44e-2)" "unprognostic (1.25e-1)" "potential prognostic favorable (7.71e-6)" "unprognostic (1.50e-1)" "potential prognostic favorable (1.23e-6)" "unprognostic (2.10e-3)" "unprognostic (1.52e-2)" "unprognostic (5.57e-3)" "unprognostic (9.02e-3)" "unprognostic (7.50e-2)" "unprognostic (2.57e-1)" "unprognostic (2.30e-1)" "unprognostic (9.78e-2)" "unprognostic (1.84e-2)" "unprognostic (2.55e-1)" "unprognostic (3.93e-2)" "unprognostic (2.78e-2)" "unprognostic (4.70e-2)" "unprognostic (3.51e-1)" "unprognostic (7.02e-2)" "unprognostic (1.92e-1)" "unprognostic (3.14e-1)" "unprognostic (9.45e-2)" MAPKAPK5 "MK5, PRAK" ENSG00000089022 "MAPK activated protein kinase 5" Q8IW41 12 111842228-111902222 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004546, HPA015515" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 16: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 10 Nucleoplasm Cytosol "CAB004546: , HPA015515: " "unprognostic (1.28e-1)" "unprognostic (2.11e-2)" "unprognostic (8.48e-3)" "unprognostic (9.24e-2)" "unprognostic (6.92e-2)" "unprognostic (1.85e-1)" "unprognostic (4.10e-2)" "unprognostic (9.21e-2)" "unprognostic (2.60e-1)" "potential prognostic unfavorable (2.31e-4)" "unprognostic (1.21e-3)" "unprognostic (4.14e-2)" "unprognostic (6.80e-3)" "validated prognostic unfavorable (9.68e-10)" "validated prognostic unfavorable (1.00e-5)" "unprognostic (1.39e-2)" "unprognostic (1.89e-3)" "unprognostic (1.99e-2)" "unprognostic (8.89e-2)" "unprognostic (1.82e-1)" "unprognostic (1.10e-1)" "unprognostic (2.09e-1)" "unprognostic (2.57e-2)" "unprognostic (1.93e-2)" "potential prognostic favorable (8.11e-4)" "unprognostic (3.11e-1)" "unprognostic (1.05e-1)" "unprognostic (2.05e-2)" "unprognostic (1.23e-1)" "unprognostic (6.86e-2)" "unprognostic (2.74e-2)" MAPKBP1 "KIAA0596, NPHP20" ENSG00000137802 "Mitogen-activated protein kinase binding protein 1" O60336 15 41774434-41827855 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 69.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 256.6;Cone photoreceptor cells: 335.4;Sertoli cells: 216.1;Suprabasal keratinocytes: 222.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030832, HPA030833" Approved Supported "Nucleoplasm,Nucleoli,Nucleoli rim" No No "Cluster 32: Basophils - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 26: Keratinocytes - Keratinization" 51 "Nucleoli, Nucleoli rim" Nucleoplasm "HPA030832: , HPA030833: " "unprognostic (1.20e-1)" "unprognostic (5.34e-2)" "unprognostic (1.02e-1)" "unprognostic (4.11e-2)" "unprognostic (1.10e-1)" "unprognostic (2.04e-1)" "unprognostic (1.55e-2)" "potential prognostic favorable (8.10e-4)" "unprognostic (4.15e-1)" "unprognostic (3.41e-2)" "unprognostic (3.25e-3)" "unprognostic (2.27e-3)" "unprognostic (1.26e-1)" "unprognostic (8.49e-3)" "unprognostic (3.74e-1)" "unprognostic (3.71e-2)" "unprognostic (9.55e-2)" "unprognostic (2.26e-1)" "unprognostic (6.03e-3)" "unprognostic (1.18e-3)" "unprognostic (3.42e-2)" "unprognostic (6.59e-3)" "potential prognostic unfavorable (1.09e-4)" "unprognostic (6.39e-2)" "unprognostic (1.61e-1)" "unprognostic (2.29e-3)" "unprognostic (1.71e-1)" "unprognostic (3.35e-2)" "unprognostic (2.47e-1)" "unprognostic (5.79e-2)" "unprognostic (2.18e-2)" MAPRE1 EB1 ENSG00000101367 "Microtubule associated protein RP/EB family member 1" Q15691 20 32819954-32850405 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Megakaryocytes: 278.2;Neutrophils: 304.3;Platelets: 287.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003600, CAB009337, CAB019391" Supported Supported "Centrosome,Basal body,Cytosol" NA NA 4500000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 27: Non-specific - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 386 "Centrosome, Cytosol" "Basal body" "CAB009337: , CAB019391: , HPA003600: " "unprognostic (1.24e-1)" "unprognostic (1.29e-1)" "unprognostic (5.79e-2)" "unprognostic (1.21e-3)" "unprognostic (7.19e-2)" "unprognostic (1.74e-1)" "unprognostic (1.29e-1)" "unprognostic (1.96e-1)" "unprognostic (7.07e-2)" "unprognostic (5.76e-3)" "potential prognostic favorable (3.21e-5)" "unprognostic (1.61e-1)" "unprognostic (1.02e-1)" "potential prognostic unfavorable (1.25e-4)" "unprognostic (8.68e-3)" "unprognostic (1.98e-2)" "unprognostic (3.97e-3)" "unprognostic (7.87e-2)" "unprognostic (9.30e-2)" "unprognostic (2.52e-2)" "unprognostic (1.30e-3)" "unprognostic (2.10e-2)" "unprognostic (8.45e-2)" "unprognostic (1.04e-1)" "unprognostic (1.12e-1)" "unprognostic (9.23e-2)" "unprognostic (1.11e-1)" "unprognostic (1.08e-2)" "unprognostic (2.39e-1)" "unprognostic (7.10e-3)" "unprognostic (5.12e-2)" MAPRE2 "EB1, EB2, RP1" ENSG00000166974 "Microtubule associated protein RP/EB family member 2" Q15555 18 34976928-35143470 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 130.8" "Cell type enhanced" "Detected in many" "Myonuclei: 445.8;NK-cells: 490.8;Retinal bipolar cells: 422.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal cortex cells, Colon - Enteric glia cells, Kidney - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016738, HPA016739" Enhanced NA NA 8200000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 42 "HPA016738: , HPA016739: " "unprognostic (1.18e-1)" "unprognostic (3.24e-1)" "unprognostic (2.46e-1)" "unprognostic (3.09e-2)" "unprognostic (5.22e-2)" "unprognostic (7.30e-3)" "unprognostic (4.38e-1)" "unprognostic (8.07e-3)" "unprognostic (2.81e-1)" "unprognostic (2.37e-1)" "validated prognostic favorable (2.77e-6)" "validated prognostic favorable (4.08e-4)" "unprognostic (1.79e-3)" "unprognostic (3.53e-3)" "unprognostic (1.13e-1)" "unprognostic (2.75e-1)" "unprognostic (2.08e-2)" "unprognostic (1.29e-2)" "unprognostic (1.64e-1)" "unprognostic (8.66e-2)" "unprognostic (3.07e-1)" "unprognostic (1.20e-1)" "unprognostic (4.81e-2)" "unprognostic (3.71e-2)" "unprognostic (3.36e-3)" "unprognostic (1.76e-2)" "unprognostic (5.50e-2)" "unprognostic (4.48e-2)" "unprognostic (2.55e-2)" "unprognostic (6.98e-3)" "unprognostic (3.10e-1)" MAPRE3 "EB3, RP3" ENSG00000084764 "Microtubule associated protein RP/EB family member 3" Q9UPY8 2 26970637-27027219 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 161.0;skeletal muscle: 139.6" "Cell type enhanced" "Detected in many" "Early spermatids: 554.1;Fallopian tube ciliated cells: 166.3;Late spermatids: 402.0;Respiratory ciliated cells: 153.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 3.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Pituitary gland - Lactotropes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009263 Uncertain NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 1: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 72 "HPA009263: " "unprognostic (1.54e-1)" "unprognostic (2.51e-2)" "unprognostic (1.19e-1)" "unprognostic (8.06e-2)" "unprognostic (4.25e-2)" "unprognostic (1.15e-1)" "unprognostic (1.81e-3)" "unprognostic (3.42e-1)" "unprognostic (3.80e-2)" "unprognostic (9.94e-2)" "unprognostic (1.92e-1)" "unprognostic (8.67e-2)" "unprognostic (2.03e-1)" "unprognostic (8.96e-3)" "unprognostic (1.88e-3)" "potential prognostic favorable (3.66e-4)" "unprognostic (1.58e-1)" "unprognostic (7.29e-2)" "unprognostic (5.62e-2)" "unprognostic (4.65e-1)" "unprognostic (3.44e-1)" "unprognostic (2.52e-2)" "unprognostic (1.03e-3)" "unprognostic (2.93e-1)" "unprognostic (7.76e-2)" "unprognostic (8.14e-2)" "unprognostic (2.31e-1)" "unprognostic (2.57e-2)" "unprognostic (7.66e-2)" "unprognostic (1.10e-1)" "unprognostic (1.47e-2)" MAPT "DDPAC, FLJ31424, FTDP-17, MAPTL, MGC138549, MSTD, MTBT1, MTBT2, PPND, PPP1R103, tau, tau-40" ENSG00000186868 "Microtubule associated protein tau" P10636 17 45894527-46028334 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Alzheimer disease, Disease variant, FDA approved drug targets, Neurodegeneration, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 147.9;skeletal muscle: 83.6" "Group enriched" "Detected in many" 4 "Astrocytes: 295.6;Bergmann glia: 241.1;Brain excitatory neurons: 320.3;Brain inhibitory neurons: 251.0;Late spermatids: 124.4;Oligodendrocyte progenitor cells: 237.0;Oligodendrocytes: 379.1;Other brain neurons: 295.2;Podocytes: 104.3;Proximal tubule cells: 158.5" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 30.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.7" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 4 "Bone cancer: 46.4;Neuroblastoma: 13.7" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal medulla cells, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Prostate - Smooth muscle cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000151, HPA048895, HPA069524, HPA069570, CAB072344" Enhanced Supported "Nuclear speckles,Plasma membrane,End piece" "Secreted to blood" "No annotated function" NA NA 82000 "Cluster 10: Brain - Synaptic signal transduction" "Cluster 14: Neurons - Synaptic function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 218 "Plasma membrane, End piece" "Nuclear speckles" "CAB000151: , CAB072344: , HPA048895: , HPA069524: , HPA069570: " "unprognostic (1.23e-1)" "unprognostic (8.49e-3)" "unprognostic (1.19e-1)" "unprognostic (2.85e-1)" "potential prognostic favorable (6.46e-4)" "unprognostic (1.10e-1)" "potential prognostic favorable (6.36e-9)" "unprognostic (1.27e-3)" "unprognostic (7.13e-2)" "potential prognostic unfavorable (6.92e-5)" "unprognostic (5.22e-2)" "unprognostic (2.30e-2)" "unprognostic (3.42e-2)" "unprognostic (9.86e-2)" "unprognostic (7.28e-2)" MARCHF1 "FLJ20668, MARCH-I, MARCH1, RNF171" ENSG00000145416 "Membrane associated ring-CH-type finger 1" Q8TCQ1 4 163524298-164384050 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 29.3;retina: 21.3" "Cell type enhanced" "Detected in many" "B-cells: 788.7;Cone photoreceptor cells: 2192.3;Corticotrophs: 581.3;Kupffer cells: 563.7;Lactotrophs: 1336.2;Oligodendrocyte progenitor cells: 1400.5;Oligodendrocytes: 1945.9;Other brain neurons: 787.2;Retinal amacrine cells: 608.6;Rod photoreceptor cells: 2793.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 94 "classical monocyte: 41.8;eosinophil: 25.5;intermediate monocyte: 41.0;memory B-cell: 42.4;myeloid DC: 44.2;naive B-cell: 35.9;non-classical monocyte: 45.6;plasmacytoid DC: 16.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adrenal gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014600, HPA048024" Uncertain Supported "Endoplasmic reticulum,Golgi apparatus,Vesicles" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 109: Neurons - Neuronal signaling" 2 Vesicles "Endoplasmic reticulum, Golgi apparatus" "HPA014600: , HPA048024: " "unprognostic (7.88e-3)" "unprognostic (6.06e-2)" "unprognostic (4.79e-2)" "unprognostic (2.95e-2)" "unprognostic (6.81e-2)" "unprognostic (2.35e-1)" "unprognostic (5.98e-3)" "unprognostic (7.91e-2)" "unprognostic (4.01e-1)" "unprognostic (8.76e-2)" "unprognostic (1.11e-1)" "unprognostic (1.84e-1)" "unprognostic (1.46e-2)" "unprognostic (3.18e-2)" "unprognostic (4.25e-2)" "unprognostic (3.76e-1)" "unprognostic (1.41e-1)" "unprognostic (3.06e-2)" "unprognostic (2.09e-1)" "unprognostic (6.37e-2)" "unprognostic (7.34e-2)" "unprognostic (6.15e-2)" "unprognostic (1.71e-2)" "unprognostic (7.25e-2)" "unprognostic (7.25e-2)" "unprognostic (2.73e-2)" "unprognostic (4.65e-2)" "unprognostic (1.34e-1)" MARCHF10 "FLJ35757, MARCH-X, MARCH10, RNF190" ENSG00000173838 "Membrane associated ring-CH-type finger 10" Q8NA82 17 62701314-62808344 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 130.2" "Cell type enhanced" "Detected in many" "Early spermatids: 618.2;Ependymal cells: 211.5;Fallopian tube ciliated cells: 142.3;Gonadotrophs: 141.9;Late primary spermatocytes: 357.1;Late spermatids: 1992.4;Respiratory ciliated cells: 245.7" "Group enriched" "Detected in many" 6 "choroid plexus epithelial cell: 60.3;ependymal cell: 217.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 4.0" "Kidney - Intercalated cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA023322 Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 5: Rhabdoid - Unknown function" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 5 "Plasma membrane, Cytosol" "HPA023322: " "unprognostic (7.73e-2)" "unprognostic (2.51e-3)" "unprognostic (1.50e-1)" "unprognostic (1.45e-1)" "unprognostic (1.59e-1)" "unprognostic (4.18e-2)" "unprognostic (9.51e-2)" "unprognostic (1.61e-1)" MARCHF11 "MARCH-XI, MARCH11, RNF226" ENSG00000183654 "Membrane associated ring-CH-type finger 11" A6NNE9 5 16067139-16180762 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 78.6" "Cell type enhanced" "Detected in some" "Brain inhibitory neurons: 124.7;Cardiomyocytes: 611.8;Early spermatids: 162.5;Gonadotrophs: 78.0;Lactotrophs: 142.7;Late primary spermatocytes: 163.6;Other brain neurons: 87.5;Retinal amacrine cells: 125.3;Retinal ganglion cells: 305.2;Somatotrophs: 355.4;Thyrotrophs: 503.0" "Cell type enhanced" "Detected in all" "cerebellar inhibitory: 578.7;mammillary body: 481.5" "Cancer enriched" "Detected in some" 5 "Kidney Chromophobe (TCGA): 6.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 12 "Neuroblastoma: 83.4" "Adrenal gland - Adrenal medulla cells, Heart muscle - Cardiomyocytes, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" "unprognostic (1.75e-2)" "unprognostic (9.83e-2)" "unprognostic (4.99e-1)" "unprognostic (4.23e-1)" MARCHF2 "HSPC240, MARCH-II, MARCH2, RNF172" ENSG00000099785 "Membrane associated ring-CH-type finger 2" Q9P0N8 19 8413270-8439017 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Endocytosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 7 "Megakaryocytes: 506.9;Platelets: 1774.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014063 Approved Supported "Endoplasmic reticulum,Cytosol" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 47: Platelets - Hemostasis" 29 "Endoplasmic reticulum" Cytosol "HPA014063: " "unprognostic (3.71e-2)" "unprognostic (1.44e-2)" "unprognostic (1.95e-1)" "unprognostic (2.39e-1)" "unprognostic (8.81e-2)" "unprognostic (2.34e-2)" "unprognostic (3.79e-1)" "potential prognostic favorable (8.91e-4)" "unprognostic (1.71e-1)" "unprognostic (1.01e-2)" "unprognostic (1.72e-2)" "unprognostic (3.13e-3)" "unprognostic (9.73e-2)" "unprognostic (3.46e-3)" "unprognostic (1.86e-1)" "unprognostic (1.06e-1)" "unprognostic (2.39e-1)" "unprognostic (1.47e-1)" "unprognostic (1.07e-1)" "unprognostic (1.30e-1)" "unprognostic (5.28e-3)" "unprognostic (2.63e-1)" "potential prognostic unfavorable (4.61e-4)" "unprognostic (2.69e-2)" "unprognostic (7.90e-2)" "unprognostic (1.51e-1)" "unprognostic (1.75e-1)" "unprognostic (6.18e-2)" "unprognostic (7.81e-2)" MARCHF3 "MARCH-III, MARCH3, MGC48332, RNF173" ENSG00000173926 "Membrane associated ring-CH-type finger 3" Q86UD3 5 126867714-127030558 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Endocytosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Mast cells: 895.6;Microglia: 462.1;Neutrophils: 550.0;Retinal horizontal cells: 482.8" "Cell type enhanced" "Detected in all" "astrocyte: 430.3;central nervous system macrophage: 575.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 10.6;naive B-cell: 12.1" "Lineage enriched" "Detected in many" 4 "B-cells: 12.1" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Skin - Keratinocyte (granular), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043406 Uncertain Supported Vesicles NA NA "Cluster 34: B-cells - Unknown function" "Cluster 40: Non-specific - Mixed function" "Cluster 44: Non-specific - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 103: Non-specific - Basic cellular processes" 4 Vesicles "HPA043406: " "unprognostic (2.25e-2)" "unprognostic (2.12e-2)" "unprognostic (1.51e-1)" "unprognostic (2.21e-1)" "unprognostic (1.69e-2)" "unprognostic (6.52e-3)" "unprognostic (4.35e-3)" "unprognostic (4.56e-2)" "potential prognostic unfavorable (1.23e-4)" "potential prognostic favorable (7.78e-4)" "unprognostic (2.55e-1)" "unprognostic (1.60e-2)" "unprognostic (3.68e-1)" "unprognostic (1.89e-3)" "unprognostic (2.43e-1)" "unprognostic (2.04e-1)" "unprognostic (6.48e-2)" "unprognostic (2.72e-1)" "unprognostic (2.26e-2)" "unprognostic (2.43e-1)" "unprognostic (1.07e-1)" "unprognostic (2.35e-2)" "unprognostic (3.21e-1)" "unprognostic (1.60e-1)" "unprognostic (3.58e-2)" "unprognostic (2.74e-2)" "unprognostic (3.35e-1)" "unprognostic (2.04e-2)" MARCHF4 "KIAA1399, MARCH-IV, MARCH4, RNF174" ENSG00000144583 "Membrane associated ring-CH-type finger 4" Q9P2E8 2 216257865-216372483 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "brain: 7.2;pituitary gland: 5.3" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 63.8;Brain excitatory neurons: 52.9;Brain inhibitory neurons: 102.1;Gonadotrophs: 182.9;Lactotrophs: 120.2;Megakaryocytes: 43.3;Neuroendocrine cells: 96.9;Other brain neurons: 92.2;Pancreatic islet cells: 71.4;Retinal amacrine cells: 47.7;Somatotrophs: 59.6;Thyrotrophs: 144.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Adrenocortical cancer: 79.6" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA014348 Approved NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 3 "HPA014348: " "unprognostic (9.00e-3)" "unprognostic (7.35e-3)" MARCHF5 "FLJ20445, MARCH-V, MARCH5, MITOL, RNF153" ENSG00000198060 "Membrane associated ring-CH-type finger 5" Q9NX47 10 92291167-92353964 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 684.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056596 Supported Mitochondria NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 52: Non-specific - Mitochondria" "Cluster 84: Apical squamous epithelium - Cornification" 61 Mitochondria "HPA056596: " "unprognostic (3.57e-1)" "unprognostic (2.25e-3)" "unprognostic (2.60e-1)" "unprognostic (9.01e-2)" "unprognostic (3.21e-2)" "unprognostic (8.06e-3)" "potential prognostic favorable (7.41e-4)" "unprognostic (2.06e-2)" "unprognostic (2.55e-1)" "potential prognostic favorable (5.52e-5)" "unprognostic (3.99e-2)" "unprognostic (2.60e-1)" "unprognostic (2.07e-1)" "unprognostic (9.96e-3)" "unprognostic (2.79e-1)" "unprognostic (1.41e-1)" "unprognostic (6.44e-2)" "unprognostic (1.16e-2)" "unprognostic (1.38e-1)" "unprognostic (5.62e-3)" "unprognostic (5.68e-3)" "unprognostic (2.41e-2)" "unprognostic (1.02e-2)" "unprognostic (6.43e-2)" "unprognostic (4.72e-2)" "unprognostic (1.05e-1)" "unprognostic (2.81e-1)" "unprognostic (2.25e-1)" "unprognostic (3.15e-1)" MARCHF6 "MARCH-VI, MARCH6, RNF176, TEB4" ENSG00000145495 "Membrane associated ring-CH-type finger 6" O60337 5 10353695-10440388 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase Epilepsy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040841, HPA063246" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 32: Basophils - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 29: Non-specific - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 7 "Endoplasmic reticulum" "HPA040841: , HPA063246: " "unprognostic (1.23e-1)" "unprognostic (1.39e-2)" "unprognostic (2.22e-2)" "unprognostic (2.00e-1)" "unprognostic (1.08e-1)" "unprognostic (3.83e-1)" "unprognostic (1.24e-1)" "unprognostic (2.33e-1)" "unprognostic (2.63e-2)" "potential prognostic favorable (3.09e-6)" "unprognostic (1.79e-2)" "unprognostic (4.74e-2)" "unprognostic (8.38e-3)" "unprognostic (3.08e-1)" "potential prognostic unfavorable (1.26e-4)" "unprognostic (9.70e-2)" "unprognostic (1.77e-1)" "unprognostic (2.43e-1)" "unprognostic (1.69e-1)" "unprognostic (9.10e-2)" "potential prognostic unfavorable (5.89e-4)" "unprognostic (1.09e-1)" "unprognostic (1.49e-2)" "unprognostic (3.10e-1)" "unprognostic (8.55e-2)" "unprognostic (2.32e-2)" "unprognostic (1.75e-1)" "unprognostic (1.74e-2)" "unprognostic (1.27e-1)" MARCHF7 "AXOT, MARCH-VII, MARCH7, RNF177" ENSG00000136536 "Membrane associated ring-CH-type finger 7" Q9H992 2 159712457-159771027 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 586.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014275, HPA022152" Enhanced Approved "Plasma membrane,Basal body,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 61: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 24: Neutrophils - Innate immunity signal integration" 42 "Plasma membrane, Cytosol" "Basal body" "HPA014275: , HPA022152: " "unprognostic (4.47e-2)" "unprognostic (1.48e-1)" "unprognostic (7.71e-2)" "unprognostic (1.59e-1)" "unprognostic (4.46e-2)" "unprognostic (3.28e-1)" "unprognostic (3.04e-2)" "unprognostic (1.79e-1)" "potential prognostic unfavorable (9.90e-4)" "potential prognostic favorable (9.41e-5)" "unprognostic (2.49e-2)" "unprognostic (8.63e-2)" "unprognostic (4.66e-3)" "unprognostic (2.34e-1)" "unprognostic (4.48e-2)" "unprognostic (3.78e-2)" "unprognostic (1.47e-1)" "unprognostic (5.73e-2)" "unprognostic (1.60e-3)" "unprognostic (5.14e-3)" "potential prognostic unfavorable (7.63e-4)" "unprognostic (1.05e-1)" "unprognostic (1.27e-1)" "unprognostic (6.74e-3)" "unprognostic (8.34e-2)" "unprognostic (1.22e-2)" "unprognostic (1.94e-1)" "unprognostic (4.88e-2)" "unprognostic (9.44e-2)" MARCHF8 "c-MIR, CMIR, MARCH-VIII, MARCH8, MIR, RNF178" ENSG00000165406 "Membrane associated ring-CH-type finger 8" Q5T0T0 10 45454585-45594906 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 291.9;Early spermatids: 393.3;Late spermatids: 165.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014597 Approved NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 6: Non-specific - Immune response" "Cluster 52: Non-specific - Mitochondria" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 16 "HPA014597: " "unprognostic (1.42e-1)" "unprognostic (6.91e-2)" "unprognostic (1.32e-2)" "unprognostic (2.51e-1)" "unprognostic (2.78e-1)" "unprognostic (2.16e-2)" "potential prognostic favorable (1.05e-4)" "unprognostic (7.14e-3)" "unprognostic (5.63e-2)" "potential prognostic favorable (4.58e-10)" "unprognostic (3.20e-3)" "unprognostic (7.64e-2)" "unprognostic (2.60e-1)" "unprognostic (6.04e-2)" "unprognostic (2.63e-2)" "unprognostic (7.03e-3)" "unprognostic (4.77e-2)" "unprognostic (2.50e-1)" "potential prognostic unfavorable (5.17e-5)" "unprognostic (6.93e-2)" "unprognostic (2.16e-1)" "unprognostic (1.27e-1)" "unprognostic (4.14e-2)" "unprognostic (1.10e-1)" "unprognostic (2.71e-1)" "unprognostic (3.98e-2)" "unprognostic (2.75e-1)" "unprognostic (4.23e-2)" "unprognostic (2.76e-2)" MARCHF9 "FLJ36578, MARCH9, RNF179" ENSG00000139266 "Membrane associated ring-CH-type finger 9" Q86YJ5 12 57755103-57760411 "Enzymes, Essential proteins, Metabolic proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 74.5;pDCs: 70.0;Rod photoreceptor cells: 87.5" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 125.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 1 "unprognostic (5.52e-3)" "unprognostic (1.48e-1)" "unprognostic (2.41e-1)" "unprognostic (2.82e-2)" "unprognostic (1.39e-1)" "unprognostic (2.66e-1)" "unprognostic (1.81e-3)" "unprognostic (2.26e-1)" "unprognostic (7.07e-2)" "potential prognostic favorable (6.89e-5)" "unprognostic (8.04e-3)" "unprognostic (1.40e-1)" "unprognostic (4.51e-3)" "unprognostic (4.70e-3)" "unprognostic (7.25e-2)" "unprognostic (4.92e-3)" "unprognostic (2.71e-3)" "unprognostic (3.50e-2)" "unprognostic (5.81e-2)" "unprognostic (7.58e-3)" "unprognostic (2.50e-3)" "unprognostic (2.49e-3)" "unprognostic (1.48e-2)" "unprognostic (2.98e-1)" "unprognostic (7.28e-2)" "unprognostic (6.98e-2)" "unprognostic (3.97e-1)" "unprognostic (3.48e-2)" "unprognostic (3.88e-2)" MARCKS "80K-L, MACS, PKCSL" ENSG00000277443 "Myristoylated alanine rich protein kinase C substrate" P29966 6 113857345-113863475 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 931.9;Neutrophils: 1059.3;Urothelial cells: 964.5" "Cell type enhanced" "Detected in all" "oligodendrocyte precursor cell: 489.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 12.8;neutrophil: 18.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022062, HPA067595, HPA069443" Enhanced Supported "Nucleoplasm,Plasma membrane,Primary cilium,Cytosol" NA NA 8500000 "Cluster 40: Monocytes - Innate immune response" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 22: Non-specific - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 21 "Plasma membrane" "Nucleoplasm, Primary cilium, Cytosol" "CAB022062: , HPA067595: , HPA069443: " "unprognostic (6.09e-3)" "unprognostic (1.12e-1)" "unprognostic (2.67e-1)" "potential prognostic unfavorable (3.52e-4)" "unprognostic (7.71e-2)" "unprognostic (2.32e-1)" "unprognostic (5.78e-2)" "unprognostic (1.94e-2)" "unprognostic (9.95e-3)" "potential prognostic favorable (3.38e-4)" "unprognostic (9.98e-2)" "unprognostic (8.23e-2)" "validated prognostic unfavorable (1.23e-9)" "validated prognostic unfavorable (8.92e-5)" "unprognostic (6.66e-3)" "unprognostic (3.11e-3)" "unprognostic (1.91e-1)" "unprognostic (5.11e-2)" "unprognostic (1.41e-2)" "unprognostic (3.61e-1)" "unprognostic (2.51e-2)" "unprognostic (8.02e-2)" "unprognostic (6.57e-2)" "unprognostic (1.64e-1)" "potential prognostic unfavorable (8.43e-4)" "unprognostic (5.52e-2)" "unprognostic (6.03e-2)" "unprognostic (9.05e-2)" MARCKSL1 "F52, MacMARCKS, MLP, MLP1" ENSG00000175130 "MARCKS like 1" P49006 1 32333839-32336233 "Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1097.7" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 511.5;Breast secretory cells: 628.3;Enteric stem cells: 558.6;Granulosa cells: 862.9;Neuroendocrine cells: 524.3;Oligodendrocytes: 476.7;Ovarian stromal cells: 606.1;Peritubular myoid cells: 534.7;Tuft cells: 1026.0" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 298.1;oligodendrocyte: 724.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 8 "eosinophil: 253.1" "Lineage enriched" "Detected in all" 8 "granulocytes: 253.1" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020787, HPA030528" Enhanced Approved "Endoplasmic reticulum,Plasma membrane,Cytokinetic bridge,Mitotic spindle,Primary cilium" Yes Yes 420000 "Cluster 22: Eosinophils - Transcription" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 15: Non-specific - Protein processing" 18 "Plasma membrane" "Endoplasmic reticulum, Cytokinetic bridge, Mitotic spindle, Primary cilium" "CAB020787: , HPA030528: " "unprognostic (1.81e-2)" "unprognostic (4.32e-1)" "unprognostic (5.61e-2)" "unprognostic (1.28e-1)" "unprognostic (7.66e-2)" "unprognostic (1.30e-1)" "unprognostic (7.78e-2)" "potential prognostic favorable (6.33e-5)" "unprognostic (3.58e-2)" "unprognostic (9.02e-2)" "unprognostic (2.39e-1)" "unprognostic (1.16e-2)" "unprognostic (2.99e-1)" "validated prognostic unfavorable (8.35e-7)" "validated prognostic unfavorable (7.27e-6)" "unprognostic (7.80e-2)" "unprognostic (3.00e-3)" "unprognostic (2.25e-1)" "unprognostic (1.75e-1)" "unprognostic (4.63e-2)" "unprognostic (3.18e-2)" "unprognostic (3.47e-1)" "unprognostic (2.12e-3)" "unprognostic (1.02e-1)" "unprognostic (1.59e-1)" "unprognostic (2.13e-1)" "unprognostic (1.05e-1)" "unprognostic (3.25e-2)" "unprognostic (4.32e-2)" "unprognostic (3.15e-2)" "unprognostic (8.37e-3)" MARCO "SCARA2, SR-A6" ENSG00000019169 "Macrophage receptor with collagenous structure" Q9UEW3 2 118942194-118994660 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 88.8;lung: 188.3;lymphoid tissue: 83.1" "Cell type enriched" "Detected in some" 15 "Kupffer cells: 4067.9" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 12.9;leukocyte: 3.8" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 49.6" "Region enhanced" "Detected in many" "thalamus: 28.0" "Group enriched" "Detected in some" 4 "classical monocyte: 33.8;intermediate monocyte: 56.6" "Lineage enriched" "Detected in many" 5 "monocytes: 56.6" "Cancer enhanced" "Detected in some" "Esophageal cancer: 1.2;lymphoma: 1.2" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Minor Salivary Gland - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Spleen - Macrophages, Thyroid gland - Macrophages" "Not detected" "Not detected" "Not detected" "Not detected" HPA063793 Enhanced Approved "Golgi apparatus,Vesicles" NA NA 8900000 "Cluster 40: Monocytes - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 50: Lymphoma - Unknown function" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" "Golgi apparatus" Vesicles "HPA063793: " "unprognostic (8.13e-3)" "unprognostic (9.56e-2)" "unprognostic (8.31e-2)" "unprognostic (1.67e-1)" "unprognostic (7.53e-2)" "unprognostic (2.65e-1)" "potential prognostic unfavorable (8.87e-4)" "unprognostic (6.79e-3)" "unprognostic (1.38e-2)" "unprognostic (5.02e-2)" "unprognostic (5.87e-3)" "unprognostic (2.10e-2)" "unprognostic (5.14e-2)" "unprognostic (1.84e-1)" "unprognostic (8.50e-2)" "unprognostic (6.11e-2)" "unprognostic (2.16e-1)" "unprognostic (6.87e-3)" "unprognostic (1.49e-1)" "unprognostic (1.35e-1)" "unprognostic (1.06e-1)" "unprognostic (6.50e-3)" "unprognostic (2.97e-1)" "unprognostic (2.84e-3)" "unprognostic (1.26e-1)" "unprognostic (1.71e-1)" "unprognostic (2.28e-1)" "unprognostic (9.21e-2)" "unprognostic (1.37e-1)" "unprognostic (2.09e-1)" MARCOL ENSG00000248109 "MARCO like" A0A1B0GUY1 5 148221650-148243580 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "urinary bladder: 1.3" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 36.3;Distal convoluted tubule cells: 6.0;Loop of henle epithelial cells: 3.5;Myonuclei: 3.8;Oocytes: 4.6;Podocytes: 9.3;Proximal tubule cells: 12.9;Renal collecting duct intercalated cells: 4.2;Renal connecting tubule cells: 6.4;Retinal horizontal cells: 4.0" "Cell type enhanced" "Detected in some" "oligodendrocyte: 2.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 27 "cervical cancer: 112.2" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" "unprognostic (8.50e-2)" "unprognostic (2.02e-2)" MARF1 "KIAA0430, LKAP, LMKB, PPP1R34" ENSG00000166783 "Meiosis regulator and mRNA stability factor 1" Q9Y4F3 16 15594387-15643154 "Predicted intracellular proteins" "Differentiation, Meiosis, Oogenesis" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 38.2;Bergmann glia: 38.7;Choroid plexus epithelial cells: 42.4;Distal convoluted tubule cells: 51.8;Loop of henle epithelial cells: 44.3;Microglia: 57.3;Oligodendrocyte progenitor cells: 38.7;Oligodendrocytes: 53.5;Papillary tip epithelial cells: 37.8;Podocytes: 60.4;Proximal tubule cells: 50.5;Renal collecting duct intercalated cells: 37.7;Renal connecting tubule cells: 41.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017992 Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 102: Non-specific - Mixed function" 20 "Golgi apparatus, Vesicles" "HPA017992: " "unprognostic (1.14e-1)" "unprognostic (9.88e-2)" "unprognostic (2.68e-2)" "unprognostic (8.38e-2)" "unprognostic (2.89e-2)" "unprognostic (1.97e-1)" "unprognostic (2.80e-1)" "unprognostic (6.15e-2)" "unprognostic (1.16e-2)" "validated prognostic favorable (2.45e-7)" "validated prognostic favorable (1.39e-4)" "unprognostic (4.03e-2)" "unprognostic (1.79e-1)" "unprognostic (4.31e-2)" "unprognostic (7.04e-2)" "unprognostic (1.93e-2)" "unprognostic (3.21e-1)" "unprognostic (4.17e-3)" "unprognostic (1.11e-3)" "unprognostic (5.80e-3)" "unprognostic (4.97e-3)" "unprognostic (1.34e-1)" "unprognostic (8.44e-2)" "unprognostic (9.29e-2)" "unprognostic (2.89e-1)" "unprognostic (2.81e-2)" "unprognostic (1.05e-1)" "unprognostic (1.56e-2)" "unprognostic (8.90e-2)" MARK1 "MARK, PAR-1C" ENSG00000116141 "Microtubule affinity regulating kinase 1" Q9P0L2 1 220528136-220664461 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 270.9;Choroid plexus epithelial cells: 551.4;Endometrial glandular cells: 319.1;Retinal ganglion cells: 274.3;Urothelial cells: 337.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 11.3" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Lung - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007421, HPA008061" Uncertain NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 27 "HPA007421: , HPA008061: " "unprognostic (4.81e-2)" "unprognostic (5.41e-2)" "unprognostic (1.53e-1)" "unprognostic (5.88e-2)" "unprognostic (5.26e-2)" "unprognostic (1.65e-1)" "unprognostic (4.01e-2)" "unprognostic (2.27e-2)" "potential prognostic unfavorable (6.10e-6)" "unprognostic (6.63e-3)" "potential prognostic favorable (6.65e-4)" "unprognostic (1.13e-1)" "unprognostic (3.67e-1)" "unprognostic (1.27e-2)" "unprognostic (9.94e-2)" "unprognostic (1.22e-1)" "unprognostic (9.69e-2)" "potential prognostic favorable (4.02e-4)" "unprognostic (6.27e-2)" "unprognostic (6.56e-2)" "unprognostic (2.56e-1)" "unprognostic (8.60e-3)" "unprognostic (4.98e-3)" "unprognostic (1.88e-1)" "unprognostic (1.59e-1)" "unprognostic (1.61e-1)" MARK2 "EMK1, PAR-1, PAR-1B, Par1b" ENSG00000072518 "Microtubule affinity regulating kinase 2" Q7KZI7 11 63838928-63911020 "Enzymes, Predicted intracellular proteins" "Differentiation, Wnt signaling pathway" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 377.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038790, HPA074905" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" 71 "Plasma membrane" "Nucleoplasm, Cytosol" "HPA038790: , HPA074905: " "unprognostic (1.82e-1)" "unprognostic (8.14e-3)" "unprognostic (1.90e-2)" "unprognostic (7.82e-3)" "unprognostic (1.81e-1)" "unprognostic (4.25e-2)" "unprognostic (1.24e-1)" "unprognostic (1.88e-1)" "unprognostic (1.80e-1)" "unprognostic (5.27e-2)" "potential prognostic favorable (2.47e-6)" "unprognostic (3.83e-2)" "unprognostic (3.47e-2)" "potential prognostic unfavorable (2.43e-4)" "unprognostic (2.48e-1)" "unprognostic (2.33e-2)" "unprognostic (3.46e-3)" "unprognostic (2.68e-2)" "unprognostic (8.02e-2)" "unprognostic (2.19e-1)" "unprognostic (4.07e-2)" "unprognostic (4.25e-3)" "unprognostic (1.22e-2)" "unprognostic (3.45e-1)" "unprognostic (6.75e-2)" "unprognostic (5.00e-3)" "unprognostic (2.67e-1)" "unprognostic (2.07e-2)" "unprognostic (2.51e-1)" "unprognostic (3.25e-1)" "unprognostic (1.28e-1)" MARK3 "CTAK1, KP78, PAR-1A" ENSG00000075413 "Microtubule affinity regulating kinase 3" P27448 14 103385377-103503831 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 32 "eosinophil: 102.0" "Lineage enriched" "Detected in all" 32 "granulocytes: 102.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024652 Approved NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 59 "HPA024652: " "unprognostic (2.88e-1)" "unprognostic (1.24e-1)" "unprognostic (1.98e-1)" "unprognostic (8.86e-2)" "unprognostic (1.76e-1)" "unprognostic (9.30e-3)" "unprognostic (1.63e-1)" "potential prognostic favorable (2.20e-4)" "unprognostic (6.47e-2)" "unprognostic (3.46e-2)" "potential prognostic favorable (1.80e-6)" "unprognostic (5.29e-2)" "unprognostic (9.31e-2)" "potential prognostic unfavorable (7.17e-6)" "unprognostic (2.67e-1)" "unprognostic (1.43e-1)" "unprognostic (1.90e-1)" "unprognostic (1.61e-1)" "unprognostic (1.04e-1)" "unprognostic (3.50e-1)" "unprognostic (3.78e-1)" "unprognostic (2.39e-1)" "unprognostic (3.37e-3)" "unprognostic (1.37e-1)" "unprognostic (3.51e-2)" "unprognostic (7.40e-2)" "unprognostic (1.80e-1)" "unprognostic (8.88e-2)" "unprognostic (2.59e-1)" "unprognostic (7.95e-2)" "unprognostic (1.57e-1)" MARK4 "FLJ90097, KIAA1860, MARKL1, Nbla00650, PAR-1D" ENSG00000007047 "Microtubule affinity regulating kinase 4" Q96L34 19 45079288-45305284 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Cilium biogenesis/degradation, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Retinal horizontal cells: 370.6;Sertoli cells: 327.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039186 Approved Supported Cytosol NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 23 Cytosol "HPA039186: " "unprognostic (8.33e-2)" "unprognostic (6.98e-2)" "unprognostic (2.12e-1)" "unprognostic (1.62e-1)" "unprognostic (8.04e-2)" "unprognostic (5.55e-2)" "unprognostic (2.20e-1)" "unprognostic (1.70e-1)" "potential prognostic unfavorable (2.44e-4)" "unprognostic (3.26e-1)" "unprognostic (1.57e-3)" "unprognostic (4.86e-2)" "unprognostic (2.25e-1)" "unprognostic (3.50e-2)" "unprognostic (2.57e-1)" "unprognostic (2.09e-2)" "unprognostic (5.73e-3)" "unprognostic (4.49e-1)" "unprognostic (1.86e-2)" "unprognostic (4.74e-2)" "unprognostic (4.74e-2)" "unprognostic (5.81e-2)" "unprognostic (2.24e-2)" "unprognostic (2.38e-2)" "unprognostic (2.78e-1)" "unprognostic (6.70e-2)" "unprognostic (3.72e-2)" "unprognostic (1.64e-1)" "unprognostic (1.34e-1)" "unprognostic (2.58e-2)" "unprognostic (6.88e-3)" MARS1 "CMT2U, MARS, MetRS, SPG70" ENSG00000166986 "Methionyl-tRNA synthetase 1" P56192 12 57475445-57517569 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase, RNA-binding, tRNA-binding" "Charcot-Marie-Tooth disease, Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 249.5;Epicardial cells: 409.3;Neutrophils: 195.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004125, CAB017097" Supported Approved Supported "Cytosol,Mid piece,Principal piece,End piece" NA NA 44000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 24: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 13: Non-specific - Mixed function" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 49 Cytosol "Mid piece, Principal piece, End piece" "CAB017097: , HPA004125: " "unprognostic (2.94e-2)" "potential prognostic unfavorable (3.61e-6)" "unprognostic (4.81e-1)" "unprognostic (1.34e-1)" "unprognostic (5.50e-3)" "unprognostic (3.29e-1)" "unprognostic (2.63e-2)" "unprognostic (3.77e-3)" "unprognostic (1.34e-3)" "potential prognostic unfavorable (4.36e-7)" "unprognostic (1.59e-3)" "potential prognostic unfavorable (2.16e-5)" "potential prognostic unfavorable (2.29e-6)" "unprognostic (3.54e-2)" "unprognostic (4.69e-3)" "unprognostic (1.30e-1)" "unprognostic (9.15e-2)" "unprognostic (6.57e-2)" "unprognostic (9.43e-2)" "unprognostic (4.78e-2)" "unprognostic (4.90e-3)" "unprognostic (1.59e-2)" "unprognostic (4.04e-1)" "unprognostic (1.97e-1)" "unprognostic (1.53e-1)" "unprognostic (5.32e-2)" "unprognostic (6.64e-2)" "unprognostic (2.60e-2)" "unprognostic (1.01e-1)" MARS2 "mtMetRS, SPAX3" ENSG00000247626 "Methionyl-tRNA synthetase 2, mitochondrial" Q96GW9 2 197705369-197708395 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Deafness, Disease variant, Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035589, HPA035590" Uncertain NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" 5 "HPA035589: , HPA035590: " "unprognostic (7.17e-2)" "unprognostic (1.19e-1)" "unprognostic (2.85e-1)" "unprognostic (4.39e-2)" "unprognostic (1.39e-2)" "unprognostic (8.62e-3)" "unprognostic (1.94e-1)" "unprognostic (4.57e-2)" "unprognostic (9.45e-2)" "unprognostic (3.17e-2)" "potential prognostic favorable (9.34e-5)" "unprognostic (3.93e-2)" "unprognostic (2.06e-1)" "unprognostic (1.37e-2)" "unprognostic (3.34e-3)" "unprognostic (1.88e-1)" "unprognostic (6.60e-2)" "unprognostic (1.36e-2)" "unprognostic (2.44e-2)" "unprognostic (8.10e-2)" "unprognostic (8.20e-2)" "unprognostic (1.72e-2)" "unprognostic (2.99e-2)" "potential prognostic unfavorable (9.44e-4)" "unprognostic (1.47e-2)" "unprognostic (1.55e-1)" "unprognostic (2.13e-1)" "unprognostic (4.53e-3)" "unprognostic (2.81e-1)" "unprognostic (3.08e-2)" "unprognostic (2.50e-1)" MARVELD1 "bA548K23.8, FLJ22343, FLJ23440, GB14, MGC4415, MRVLDC1" ENSG00000155254 "MARVEL domain containing 1" Q9BSK0 10 97713173-97718150 "Predicted membrane proteins" "Cell cycle" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bergmann glia: 50.8;Breast myoepithelial cells: 61.1;Goblet cells: 41.3;Hepatic stellate cells: 51.6;Peritubular myoid cells: 44.2;Schwann cells: 65.1;Vascular smooth muscle cells: 42.1" "Cell type enhanced" "Detected in many" "Bergmann glia: 52.4;vascular associated smooth muscle cell: 52.5" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "choroid plexus: 51.1" "Immune cell enhanced" "Detected in some" "classical monocyte: 3.2;intermediate monocyte: 2.7;myeloid DC: 3.1" "Group enriched" "Detected in many" 18 "dendritic cells: 3.1;monocytes: 3.2" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Adrenal gland - Fibroblasts, Colon - Enteric glia cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 62: Smooth muscle cells - Muscle contraction" "unprognostic (4.12e-1)" "unprognostic (3.30e-2)" "unprognostic (1.76e-1)" "unprognostic (6.75e-3)" "potential prognostic unfavorable (8.00e-5)" "unprognostic (3.66e-2)" "unprognostic (6.87e-3)" "potential prognostic unfavorable (6.49e-4)" "unprognostic (8.94e-2)" "unprognostic (2.16e-3)" "unprognostic (1.98e-1)" "unprognostic (4.97e-2)" "unprognostic (2.19e-2)" "unprognostic (6.98e-3)" "unprognostic (4.21e-1)" "potential prognostic unfavorable (6.75e-6)" "unprognostic (1.35e-3)" "unprognostic (1.24e-2)" "unprognostic (3.62e-1)" "unprognostic (2.19e-3)" "unprognostic (3.73e-3)" "unprognostic (1.05e-2)" "unprognostic (6.38e-2)" "unprognostic (1.25e-2)" "unprognostic (7.40e-2)" "unprognostic (5.79e-2)" "unprognostic (1.37e-1)" "unprognostic (1.78e-3)" "unprognostic (6.76e-2)" "unprognostic (2.10e-1)" "unprognostic (2.26e-1)" MARVELD2 "DFNB49, FLJ30532, MRVLDC2, TRIC" ENSG00000152939 "MARVEL domain containing 2" Q8N4S9 5 69415065-69444330 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Hearing "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 14.6" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 26.6;Distal convoluted tubule cells: 44.4;Loop of henle epithelial cells: 43.1;Papillary tip epithelial cells: 26.1;Renal collecting duct intercalated cells: 31.6;Renal collecting duct principal cells: 21.7;Renal connecting tubule cells: 22.8" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 20.8;endothelial cell: 45.8;ependymal cell: 16.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Liver - Hepatocytes, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Region enriched" "Detected in some" 8 "cerebellum: 7.9" "Low region specificity" "Detected in all" "HPA018119, HPA061726" Uncertain Supported "Cell Junctions" NA NA "Cluster 60: Stomach - Digestion" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 4 "Cell Junctions" "HPA018119: , HPA061726: " "unprognostic (5.13e-2)" "unprognostic (2.25e-1)" "unprognostic (1.32e-1)" "unprognostic (1.44e-1)" "unprognostic (5.19e-2)" "unprognostic (7.34e-2)" "unprognostic (2.40e-2)" "unprognostic (2.21e-1)" "unprognostic (1.03e-1)" "validated prognostic favorable (1.21e-8)" "validated prognostic favorable (2.86e-5)" "unprognostic (2.11e-1)" "unprognostic (3.88e-1)" "unprognostic (3.36e-1)" "unprognostic (2.64e-2)" "unprognostic (2.44e-1)" "unprognostic (7.89e-2)" "unprognostic (2.88e-1)" "unprognostic (2.50e-2)" "unprognostic (1.16e-1)" "unprognostic (1.62e-1)" "unprognostic (5.94e-2)" "unprognostic (8.04e-2)" "unprognostic (6.28e-3)" "unprognostic (2.43e-1)" "unprognostic (3.94e-1)" "unprognostic (2.30e-1)" "unprognostic (2.74e-2)" "unprognostic (3.78e-2)" MARVELD3 MRVLDC3 ENSG00000140832 "MARVEL domain containing 3" Q96A59 16 71626161-71642114 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 31.2" "Cell type enhanced" "Detected in many" "Colonocytes: 151.6;Enteric stem cells: 69.1;Enteric transient amplifying cells: 74.7;Enterocytes: 274.3;Goblet cells: 91.6;Tuft cells: 69.2" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 9.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 1.5" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Skin - Outer root sheath cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043514, HPA045471" Approved "Vesicles,Intermediate filaments" No NA "Cluster 35: Neutrophils - Protein binding" "Cluster 77: Intestine - Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" Vesicles "Intermediate filaments" "HPA043514: , HPA045471: " "unprognostic (6.25e-3)" "unprognostic (2.85e-1)" "unprognostic (3.75e-2)" "unprognostic (1.23e-2)" "unprognostic (2.47e-1)" "unprognostic (1.91e-1)" "unprognostic (1.29e-1)" "unprognostic (3.64e-1)" "unprognostic (2.95e-2)" "unprognostic (3.98e-2)" "potential prognostic favorable (1.51e-5)" "unprognostic (1.37e-3)" "unprognostic (1.00e-3)" "unprognostic (2.17e-1)" "unprognostic (5.18e-2)" "unprognostic (1.70e-2)" "unprognostic (1.29e-1)" "unprognostic (1.26e-1)" "unprognostic (1.46e-2)" "unprognostic (6.56e-2)" "unprognostic (1.95e-1)" "unprognostic (1.00e-1)" "unprognostic (1.38e-3)" "unprognostic (4.40e-2)" "unprognostic (1.24e-1)" "unprognostic (2.54e-2)" "unprognostic (2.21e-1)" "unprognostic (4.85e-2)" "unprognostic (5.13e-1)" "unprognostic (2.70e-1)" "unprognostic (4.61e-2)" MAS1 ENSG00000130368 "MAS1 proto-oncogene, G protein-coupled receptor" P04201 6 159890988-159917447 "Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 5 "brain: 2.0" "Cell type enriched" "Detected in some" 4 "Brain excitatory neurons: 8.1" "Cell type enhanced" "Detected in some" "hippocampal CA1-3: 30.6;hippocampal CA4: 21.4;hippocampal dentate gyrus: 18.2" "Not detected" "Not detected" "Region enhanced" "Detected in many" "hippocampal formation: 23.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Smooth muscle cells" "Group enriched" "Detected in many" 22 "amygdala: 38.5;basal ganglia: 26.6;cerebral cortex: 32.4;hippocampal formation: 64.6;white matter: 18.1" "Group enriched" "Detected in some" 7 "amygdala: 7.9;cerebral cortex: 12.8;hippocampal formation: 25.7" HPA079325 Uncertain NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 29: Forebrain - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 35: Neurons - Synaptic function & neurogenesis" 3 "HPA079325: " MAS1L "dJ994E9.2, MAS-L, MRG" ENSG00000204687 "MAS1 proto-oncogene like, G protein-coupled receptor" P35410 6 29486697-29487956 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "cervix: 2.9;epididymis: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA017983 Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 38: Non-specific - Basic cellular processes" "Cluster 47: Leukemia - Hemostasis" 1 "Plasma membrane" "Nucleoplasm, Cytosol" "HPA017983: " MASP1 "CRARF, MAP-1, Map44, MASP, MASP-3, PRSS5" ENSG00000127241 "MBL associated serine protease 1" P48740 3 187217282-187291980 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Complement activation lectin pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 100.9;heart muscle: 108.6;liver: 171.6" "Cell type enhanced" "Detected in some" "Astrocytes: 61.5;Bergmann glia: 25.8;Cardiomyocytes: 60.7;Cholangiocytes: 40.1;Decidual stromal cells: 82.8;Endometrial stromal cells: 43.6;Ependymal cells: 42.5;Epididymal efferent duct absorptive cells: 28.1;Epididymal efferent duct ciliated cells: 25.6;Fibro-adipogenic progenitors: 53.1;Hepatic stellate cells: 90.4;Hepatocytes: 108.9;Oligodendrocyte progenitor cells: 37.3" "Cell type enhanced" "Detected in many" "astrocyte: 114.5;ependymal cell: 51.3;oligodendrocyte precursor cell: 42.0" "Group enriched" "Detected in many" 4 "Glioblastoma Multiforme (TCGA): 40.6;Kidney Renal Clear Cell Carcinoma (TCGA): 20.1;Kidney Renal Papillary Cell Carcinoma (TCGA): 22.8;Liver Hepatocellular Carcinoma (TCGA): 28.4;Prostate Adenocarcinoma (TCGA): 14.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 11.8;Rhabdoid: 14.6" "Adipose visceral - Mast cells, Breast - Fibroblasts, Heart muscle - Cardiomyocytes, Pancreas - Fibroblasts, Prostate - Smooth muscle cells, Skin - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001617, HPA009641" Supported Enhanced Nucleoplasm,Cytosol "Secreted to blood" Immunity No NA 8670000000 2200000000 "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 28: Astrocytes - Homeostasis & neuron support" 3 "Nucleoplasm, Cytosol" "HPA001617: , HPA009641: " "unprognostic (6.70e-2)" "unprognostic (1.13e-3)" "unprognostic (1.17e-1)" "unprognostic (1.20e-1)" "unprognostic (4.39e-2)" "unprognostic (4.86e-2)" "potential prognostic favorable (8.75e-6)" "unprognostic (1.49e-2)" "validated prognostic favorable (2.10e-6)" "validated prognostic favorable (2.18e-4)" "unprognostic (2.97e-1)" "unprognostic (1.08e-3)" "potential prognostic favorable (2.16e-4)" "unprognostic (5.65e-3)" "unprognostic (1.67e-1)" "unprognostic (1.27e-1)" "unprognostic (2.15e-1)" "unprognostic (4.35e-1)" "unprognostic (5.26e-2)" "unprognostic (2.32e-1)" "unprognostic (1.33e-1)" "unprognostic (9.69e-2)" "unprognostic (6.74e-2)" "unprognostic (5.01e-2)" MASP2 "MAP-2, Map19, MASP1P1, sMAP" ENSG00000009724 "MBL associated serine protease 2" O00187 1 11022009-11047239 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 57 "liver: 452.9" "Cell type enhanced" "Detected in many" "Adipocytes: 70.6;Cardiomyocytes: 256.9;Epicardial cells: 170.6;Hepatocytes: 758.6;Myonuclei: 72.1" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in some" 144 "Liver Hepatocellular Carcinoma (TCGA): 239.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA029313, HPA029314" Uncertain Supported "Golgi apparatus" "Secreted to blood" "Complement pathway" NA NA 340000000 600000000 "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 2: Neurons - Nucleosome" "Cluster 18: Liver cancer - Metabolism" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 6 "Golgi apparatus" "HPA029313: , HPA029314: " "unprognostic (2.33e-1)" "unprognostic (1.53e-1)" "unprognostic (1.61e-1)" "unprognostic (2.69e-3)" "validated prognostic favorable (8.18e-4)" "validated prognostic favorable (5.30e-4)" "unprognostic (6.75e-2)" "unprognostic (5.55e-3)" "unprognostic (4.09e-1)" MAST1 "KIAA0973, SAST" ENSG00000105613 "Microtubule associated serine/threonine kinase 1" Q9Y2H9 19 12833951-12874952 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 92.5" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 103.4;Brain inhibitory neurons: 75.7;Cone photoreceptor cells: 101.4;Early spermatids: 44.9;Lactotrophs: 62.9;Late spermatids: 62.8;Other brain neurons: 107.5;Retinal amacrine cells: 150.4;Retinal bipolar cells: 87.8;Retinal ganglion cells: 193.1;Retinal horizontal cells: 84.1;Rod photoreceptor cells: 75.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 7.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 23.2" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028181, HPA073106" Enhanced Supported Vesicles,Cytosol NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 17 Vesicles Cytosol "HPA028181: , HPA073106: " "unprognostic (1.36e-1)" "unprognostic (1.63e-2)" "unprognostic (1.14e-1)" "unprognostic (1.08e-3)" "unprognostic (8.50e-2)" "potential prognostic favorable (2.75e-4)" "unprognostic (2.79e-3)" "unprognostic (1.04e-2)" "unprognostic (3.57e-1)" "unprognostic (2.96e-1)" "unprognostic (4.33e-3)" "unprognostic (8.78e-3)" "unprognostic (2.44e-1)" "unprognostic (6.94e-3)" MAST2 "KIAA0807, MAST205" ENSG00000086015 "Microtubule associated serine/threonine kinase 2" Q6P0Q8 1 45786987-46036122 "Cancer-related genes, Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 161.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 352.0;Cone photoreceptor cells: 339.5;Enterocytes: 277.2;Myonuclei: 930.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.5" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Pituitary gland - Corticotropes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039722, HPA040155" Approved Approved Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 25 Cytosol "HPA039722: , HPA040155: " "unprognostic (4.81e-2)" "unprognostic (7.84e-2)" "unprognostic (2.44e-1)" "unprognostic (2.86e-2)" "unprognostic (5.67e-3)" "unprognostic (5.74e-2)" "unprognostic (2.94e-1)" "unprognostic (3.88e-3)" "unprognostic (1.13e-1)" "unprognostic (2.63e-3)" "unprognostic (3.89e-2)" "unprognostic (1.51e-2)" "potential prognostic unfavorable (4.05e-5)" "potential prognostic unfavorable (1.59e-8)" "unprognostic (3.09e-1)" "unprognostic (4.08e-2)" "unprognostic (7.68e-3)" "unprognostic (2.39e-1)" "unprognostic (1.80e-1)" "unprognostic (1.26e-1)" "unprognostic (1.03e-2)" "unprognostic (4.28e-1)" "unprognostic (2.69e-1)" "unprognostic (1.84e-1)" "unprognostic (9.68e-2)" "unprognostic (3.64e-3)" "unprognostic (9.92e-2)" "unprognostic (7.41e-2)" "unprognostic (6.24e-2)" "unprognostic (6.25e-2)" "unprognostic (1.30e-1)" MAST3 KIAA0561 ENSG00000099308 "Microtubule associated serine/threonine kinase 3" O60307 19 18097778-18151692 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 44.9" "Cell type enriched" "Detected in many" 4 "Neutrophils: 378.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035061, HPA035062" Uncertain Approved "Nuclear speckles" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 13 "Nuclear speckles" "HPA035061: , HPA035062: " "unprognostic (6.90e-2)" "unprognostic (1.03e-1)" "potential prognostic favorable (9.90e-4)" "unprognostic (2.96e-1)" "unprognostic (7.37e-2)" "unprognostic (5.58e-2)" "unprognostic (6.03e-2)" "unprognostic (2.06e-1)" "potential prognostic favorable (8.09e-4)" "unprognostic (1.01e-2)" "unprognostic (1.85e-1)" "unprognostic (6.13e-3)" "unprognostic (2.46e-1)" "unprognostic (2.07e-1)" "unprognostic (1.55e-2)" "unprognostic (1.32e-2)" "unprognostic (4.88e-2)" "unprognostic (9.59e-2)" "unprognostic (1.09e-2)" "unprognostic (9.87e-2)" "unprognostic (1.58e-2)" "unprognostic (1.48e-3)" "unprognostic (5.63e-2)" "unprognostic (3.12e-1)" "unprognostic (1.80e-2)" "unprognostic (7.55e-2)" "unprognostic (3.25e-1)" "unprognostic (1.21e-2)" "unprognostic (2.76e-1)" "unprognostic (1.61e-2)" "unprognostic (2.58e-1)" MAST4 KIAA0303 ENSG00000069020 "Microtubule associated serine/threonine kinase family member 4" O15021 5 66596380-67169593 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1832.6;Proximal tubule cells: 1393.1;Suprabasal keratinocytes: 1245.4;Urothelial cells: 2794.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 15.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Prostate - Urothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000544 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 69: Urothelial cells - Basic cellular functions" 2 "Nucleoplasm, Cytosol" "HPA000544: " "potential prognostic favorable (4.63e-4)" "unprognostic (3.73e-2)" "unprognostic (1.86e-1)" "unprognostic (1.61e-2)" "unprognostic (1.29e-1)" "unprognostic (1.93e-3)" "potential prognostic unfavorable (7.49e-4)" "unprognostic (1.29e-2)" "potential prognostic favorable (1.07e-4)" "unprognostic (8.78e-3)" "potential prognostic favorable (3.17e-8)" "unprognostic (3.22e-3)" "unprognostic (4.86e-3)" "unprognostic (1.08e-1)" "unprognostic (3.09e-2)" "unprognostic (1.08e-2)" "unprognostic (1.80e-1)" "unprognostic (5.31e-2)" "unprognostic (8.58e-2)" "unprognostic (1.40e-1)" "unprognostic (1.00e-1)" "unprognostic (8.27e-2)" "unprognostic (1.58e-1)" "unprognostic (7.93e-2)" "unprognostic (9.80e-2)" "unprognostic (8.19e-2)" "unprognostic (3.27e-2)" "unprognostic (7.16e-3)" "unprognostic (1.46e-1)" "unprognostic (8.66e-2)" "unprognostic (6.86e-2)" MASTL "FLJ14813, Gwl, THC2" ENSG00000120539 "Microtubule associated serine/threonine kinase like" Q96GX5 10 27154824-27187953 "Disease related genes, Enzymes, Essential proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Epicardial cells: 404.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA027175, HPA054273" Approved Enhanced Nucleoplasm NA Yes "Cluster 33: Non-specific - ATP binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 5: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 3 Nucleoplasm "HPA027175: , HPA054273: " "unprognostic (2.86e-1)" "unprognostic (1.89e-2)" "unprognostic (2.03e-1)" "unprognostic (7.47e-2)" "unprognostic (2.89e-1)" "unprognostic (5.66e-2)" "unprognostic (2.91e-1)" "potential prognostic favorable (6.37e-4)" "unprognostic (4.48e-3)" "potential prognostic unfavorable (1.86e-4)" "unprognostic (6.40e-2)" "unprognostic (3.11e-1)" "unprognostic (1.63e-2)" "potential prognostic unfavorable (1.01e-5)" "unprognostic (1.39e-3)" "unprognostic (1.33e-3)" "unprognostic (4.70e-3)" "unprognostic (6.32e-2)" "unprognostic (8.15e-2)" "unprognostic (1.35e-1)" "unprognostic (1.53e-1)" "potential prognostic unfavorable (1.33e-5)" "unprognostic (4.31e-3)" "unprognostic (1.04e-1)" "unprognostic (1.73e-2)" "unprognostic (1.36e-1)" "unprognostic (6.87e-2)" "unprognostic (9.22e-3)" "unprognostic (2.33e-1)" "unprognostic (9.46e-2)" "unprognostic (9.82e-2)" MAT1A "MAT, MATA1, SAMS, SAMS1" ENSG00000151224 "Methionine adenosyltransferase 1A" Q00266 10 80271820-80289658 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "One-carbon metabolism" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "liver: 1259.5" "Cell type enriched" "Detected in some" 59 "Hepatocytes: 6544.3" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 4.5;ependymal cell: 18.4;fibroblast: 4.9" "Cancer enriched" "Detected in many" 36 "Liver Hepatocellular Carcinoma (TCGA): 194.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 8.6;skin cancer: 7.2" "Liver - Hepatocytes, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA048627, HPA069459" Supported Approved Nucleoplasm,Cytosol NA NA 1200000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 3: Choroid plexus - Cilium" "Cluster 18: Liver cancer - Metabolism" "Cluster 93: Hepatocytes - Bile production & excretion" 8 Nucleoplasm Cytosol "HPA048627: , HPA069459: " "unprognostic (2.70e-1)" "unprognostic (4.23e-1)" "unprognostic (1.51e-1)" "unprognostic (2.52e-1)" "unprognostic (1.85e-3)" "validated prognostic unfavorable (6.75e-6)" "validated prognostic unfavorable (1.14e-4)" "potential prognostic unfavorable (7.98e-7)" "unprognostic (9.01e-3)" "unprognostic (1.18e-1)" "unprognostic (1.86e-1)" "unprognostic (1.50e-1)" "unprognostic (2.10e-1)" "unprognostic (3.69e-3)" "unprognostic (1.13e-1)" "unprognostic (9.63e-2)" "unprognostic (7.11e-2)" "unprognostic (1.63e-1)" "unprognostic (8.40e-2)" "unprognostic (3.92e-3)" "unprognostic (7.96e-2)" MAT2A "MATA2, MATII, SAMS2" ENSG00000168906 "Methionine adenosyltransferase 2A" P31153 2 85539168-85545281 "Enzymes, Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "One-carbon metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 825.0" "Cell type enhanced" "Detected in all" "Smooth muscle cells: 296.5" "Cell type enhanced" "Detected in all" "astrocyte: 261.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009968, HPA043028, HPA069459" Approved Approved Nucleoplasm,Cytosol NA NA 950000 "Cluster 33: Non-specific - ATP binding" "Cluster 8: Pancreas - Proteolysis" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 103: Non-specific - Basic cellular processes" 34 Nucleoplasm Cytosol "CAB009968: , HPA043028: , HPA069459: " "unprognostic (9.64e-2)" "potential prognostic unfavorable (9.80e-4)" "unprognostic (1.24e-2)" "unprognostic (1.74e-1)" "unprognostic (3.65e-1)" "unprognostic (2.18e-1)" "unprognostic (1.28e-1)" "unprognostic (2.30e-1)" "unprognostic (3.19e-2)" "unprognostic (3.33e-3)" "potential prognostic favorable (8.19e-6)" "unprognostic (1.74e-2)" "unprognostic (1.80e-1)" "potential prognostic unfavorable (6.70e-4)" "unprognostic (4.57e-3)" "unprognostic (1.48e-2)" "unprognostic (2.27e-1)" "unprognostic (2.91e-2)" "unprognostic (2.41e-2)" "unprognostic (4.82e-2)" "unprognostic (2.62e-1)" "unprognostic (2.05e-1)" "unprognostic (4.46e-3)" "unprognostic (5.19e-2)" "unprognostic (1.17e-2)" "unprognostic (3.44e-1)" "potential prognostic unfavorable (1.07e-5)" "unprognostic (8.23e-2)" "unprognostic (2.24e-1)" "unprognostic (3.78e-2)" "unprognostic (9.98e-2)" MAT2B "MATIIbeta, SDR23E1" ENSG00000038274 "Methionine adenosyltransferase 2B" Q9NZL9 5 163503114-163519558 "Metabolic proteins, Predicted intracellular proteins" "One-carbon metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 170.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037721, HPA037722" Uncertain Approved "Plasma membrane" NA NA 370000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 76: Non-specific - Metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 12 "Plasma membrane" "HPA037721: , HPA037722: " "unprognostic (7.70e-2)" "unprognostic (3.78e-2)" "unprognostic (1.57e-1)" "unprognostic (3.80e-2)" "unprognostic (7.65e-3)" "unprognostic (3.30e-2)" "unprognostic (1.59e-3)" "unprognostic (6.68e-2)" "unprognostic (3.17e-2)" "unprognostic (4.38e-2)" "validated prognostic favorable (5.18e-12)" "validated prognostic favorable (6.38e-4)" "unprognostic (1.27e-1)" "unprognostic (1.44e-1)" "unprognostic (1.88e-1)" "unprognostic (2.04e-1)" "unprognostic (2.76e-1)" "unprognostic (2.94e-2)" "unprognostic (2.50e-1)" "unprognostic (4.06e-2)" "unprognostic (6.77e-3)" "unprognostic (1.10e-3)" "unprognostic (7.70e-2)" "unprognostic (1.38e-1)" "potential prognostic favorable (4.59e-5)" "unprognostic (1.69e-1)" "unprognostic (8.18e-2)" "unprognostic (2.36e-1)" "unprognostic (1.74e-1)" "unprognostic (1.66e-1)" "unprognostic (2.41e-1)" MATCAP1 "KIAA0895L, LOC653319" ENSG00000196123 "Microtubule associated tyrosine carboxypeptidase 1" Q68EN5 16 67175599-67184040 "Enzymes, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 79.4" "Cell type enhanced" "Detected in many" "Early spermatids: 121.2;Late spermatids: 361.0;Retinal horizontal cells: 80.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065996 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 64: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 1 "Nucleoplasm, Vesicles" "HPA065996: " "unprognostic (1.69e-3)" "unprognostic (8.38e-2)" "unprognostic (2.06e-1)" "unprognostic (2.37e-1)" "potential prognostic unfavorable (4.28e-4)" "unprognostic (2.02e-2)" "unprognostic (1.15e-1)" "unprognostic (2.40e-3)" "unprognostic (8.09e-2)" "unprognostic (2.03e-2)" "unprognostic (5.51e-2)" "unprognostic (2.13e-2)" "potential prognostic favorable (1.85e-4)" "unprognostic (4.46e-2)" "potential prognostic favorable (6.81e-4)" "unprognostic (2.09e-2)" "unprognostic (7.67e-2)" "unprognostic (2.92e-1)" "unprognostic (3.68e-3)" "unprognostic (3.74e-1)" "unprognostic (6.52e-2)" "unprognostic (1.68e-3)" "unprognostic (3.32e-3)" "unprognostic (2.77e-2)" "unprognostic (4.36e-2)" "unprognostic (6.60e-2)" "unprognostic (2.26e-3)" "unprognostic (1.71e-1)" "unprognostic (3.04e-1)" "unprognostic (3.95e-1)" "unprognostic (9.89e-2)" MATCAP2 KIAA0895 ENSG00000164542 "Microtubule associated tyrosine carboxypeptidase 2" Q8NCT3 7 36324152-36390125 "Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 20.8" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 101.4;Early spermatids: 121.8;Endometrial ciliated cells: 107.3;Gastric chief cells: 104.8;Late spermatids: 108.2;Parietal cells: 100.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Stomach - Chief cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021036, HPA061066" Uncertain Approved "Nucleoplasm,Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 67: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" Nucleoplasm "Plasma membrane, Cell Junctions, Cytosol" "HPA021036: , HPA061066: " "unprognostic (4.08e-2)" "unprognostic (2.21e-2)" "unprognostic (1.53e-1)" "unprognostic (9.78e-2)" "unprognostic (2.81e-1)" "unprognostic (6.01e-2)" "unprognostic (5.20e-2)" "potential prognostic unfavorable (6.89e-4)" "unprognostic (1.58e-2)" "unprognostic (8.63e-2)" "potential prognostic favorable (9.73e-6)" "unprognostic (1.21e-1)" "unprognostic (2.06e-1)" "unprognostic (7.36e-3)" "potential prognostic unfavorable (8.22e-4)" "unprognostic (2.08e-2)" "unprognostic (9.71e-2)" "unprognostic (2.07e-1)" "unprognostic (4.30e-2)" "unprognostic (2.56e-3)" "unprognostic (1.10e-1)" "unprognostic (2.22e-1)" "unprognostic (6.51e-2)" "unprognostic (2.50e-1)" "unprognostic (1.32e-1)" "unprognostic (6.26e-2)" "unprognostic (3.04e-1)" "unprognostic (1.16e-2)" "unprognostic (1.02e-2)" "unprognostic (1.51e-2)" "unprognostic (3.60e-3)" MATK "CHK, CTK, DKFZp434N1212, HHYLTK, HYL, HYLTK, Lsk, MGC1708, MGC2101" ENSG00000007264 "Megakaryocyte-associated tyrosine kinase" P42679 19 3777970-3802129 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.3;brain: 55.6" "Group enriched" "Detected in many" 5 "NK-cells: 179.7;Tuft cells: 495.7" "Cell type enhanced" "Detected in many" "leukocyte: 70.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 77.1" "Group enriched" "Detected in many" 57 "NK-cells: 77.1;T-cells: 46.3" "Cancer enhanced" "Detected in many" "Leukemia: 56.3" "Adipose visceral - T-cells, Breast - T-cells, Prostate - T-cells, Stomach - T-cells, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004847, HPA066547" Approved Approved "Microtubules,Cytokinetic bridge,Mitotic spindle,Centriolar satellite,Cytosol" Yes NA "Cluster 15: NK-cells - Unknown function" "Cluster 78: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 11 Microtubules "Cytokinetic bridge, Mitotic spindle, Centriolar satellite, Cytosol" "HPA004847: , HPA066547: " "unprognostic (2.28e-1)" "potential prognostic favorable (3.81e-4)" "unprognostic (1.49e-2)" "unprognostic (7.38e-3)" "unprognostic (2.35e-1)" "unprognostic (2.45e-1)" "unprognostic (8.35e-2)" "unprognostic (2.44e-1)" "unprognostic (3.62e-2)" "unprognostic (1.82e-1)" "unprognostic (5.78e-3)" "unprognostic (2.65e-2)" "unprognostic (1.66e-1)" "unprognostic (1.83e-2)" "unprognostic (3.70e-2)" "unprognostic (2.16e-2)" "unprognostic (9.24e-2)" "unprognostic (7.10e-2)" "unprognostic (1.45e-1)" "potential prognostic unfavorable (5.75e-4)" "unprognostic (9.35e-2)" "unprognostic (2.07e-2)" "unprognostic (7.23e-2)" "unprognostic (3.47e-2)" "unprognostic (9.41e-2)" "unprognostic (7.92e-2)" "unprognostic (1.83e-1)" "unprognostic (5.83e-2)" "unprognostic (2.20e-1)" "unprognostic (1.21e-1)" "unprognostic (1.79e-1)" MATN1 "CMP, CRTM" ENSG00000162510 "Matrilin 1" P21941 1 30711277-30723585 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "retina: 4.6" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 11.2;Colonocytes: 23.2;Enterocytes: 18.0;Epicardial cells: 18.2;Epididymal clear cells: 67.4;Epididymal efferent duct absorptive cells: 11.1;Goblet cells: 14.3;Müller glia: 10.7;Tuft cells: 11.5" "Cell type enriched" "Detected in many" 4 "lower rhombic lip: 13.7" "Cancer enriched" "Detected in single" 5 "Thyroid Carcinoma (TCGA): 2.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" HPA028580 Supported "Secreted to extracellular matrix" "No annotated function" NA NA "Cluster 42: Retina - Visual perception" "Cluster 6: Non-specific - Immune response" "Cluster 5: Rhabdoid - Unknown function" "Cluster 65: Non-specific - Cell growth & division" 1 "HPA028580: " "unprognostic (2.41e-1)" MATN2 ENSG00000132561 "Matrilin 2" O00339 8 97868840-98036724 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bergmann glia: 217.5;Breast myoepithelial cells: 140.4;Cone photoreceptor cells: 126.3;Early spermatids: 150.8;Enterocytes: 195.5;Ependymal cells: 187.7;Hepatic stellate cells: 129.1;Late spermatids: 152.0;Leydig cells: 133.7;Oligodendrocyte progenitor cells: 143.7;Peritubular myoid cells: 321.4;Schwann cells: 269.7" "Cell type enhanced" "Detected in all" "Bergmann glia: 212.5;ependymal cell: 171.0;oligodendrocyte precursor cell: 175.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "MAIT T-cell: 5.2" "Lineage enriched" "Detected in single" 7 "T-cells: 5.2" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Colon - Enteric glia cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Spleen - Fibroblasts_2, Stomach - Fibroblasts, Testis - Peritubular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB033879 Approved "Secreted to extracellular matrix" "No annotated function" NA NA 1300000 "Cluster 1: T-cells - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 46: Brainstem - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 94: Gonadal somatic cells - Mixed function" 2 "CAB033879: " "unprognostic (2.66e-3)" "unprognostic (1.87e-1)" "unprognostic (3.76e-1)" "unprognostic (6.34e-2)" "unprognostic (3.64e-2)" "unprognostic (6.56e-2)" "unprognostic (1.73e-1)" "unprognostic (3.80e-1)" "unprognostic (1.21e-2)" "potential prognostic unfavorable (4.08e-4)" "unprognostic (2.80e-3)" "unprognostic (1.47e-1)" "potential prognostic unfavorable (5.66e-4)" "unprognostic (1.52e-1)" "unprognostic (3.58e-2)" "unprognostic (1.88e-1)" "unprognostic (1.47e-2)" "unprognostic (6.60e-2)" "unprognostic (1.48e-1)" "unprognostic (1.04e-2)" "unprognostic (7.94e-2)" "unprognostic (1.63e-1)" "unprognostic (6.29e-2)" "unprognostic (2.84e-1)" "unprognostic (3.92e-2)" "unprognostic (4.14e-2)" "unprognostic (4.28e-1)" "unprognostic (1.59e-1)" "unprognostic (5.45e-2)" "unprognostic (2.77e-3)" "unprognostic (2.00e-1)" MATN3 "EDM5, HOA" ENSG00000132031 "Matrilin 3" O15232 2 19992052-20012668 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 12.5;placenta: 10.6" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 33.6;Breast hormone-responsive cells: 9.1;Breast lactating cells: 16.5;Breast myoepithelial cells: 5.2;Endometrial secretory cells: 7.5;Pericytes: 12.8;Peritubular myoid cells: 5.1;Vascular endothelial cells: 5.2;Vascular smooth muscle cells: 12.1" "Group enriched" "Detected in some" 5 "endothelial cell: 57.3;thalamic excitatory: 23.8" "Cancer enhanced" "Detected in all" "Pancreatic Adenocarcinoma (TCGA): 24.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 29.3;testis cancer: 24.9" "Not detected" "Not detected" "Region enhanced" "Detected in some" "hypothalamus: 2.3" "HPA051250, HPA074980" Approved "Endoplasmic reticulum,Golgi apparatus,Vesicles" "Secreted to extracellular matrix" "No annotated function" NA NA 340000 "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 110: Mural cells - ECM organization" 5 "Endoplasmic reticulum, Golgi apparatus, Vesicles" "HPA051250: , HPA074980: " "unprognostic (1.79e-1)" "unprognostic (5.73e-2)" "unprognostic (1.98e-2)" "unprognostic (8.73e-3)" "unprognostic (7.30e-3)" "unprognostic (6.85e-3)" "unprognostic (2.03e-1)" "unprognostic (7.35e-3)" "unprognostic (3.58e-2)" "unprognostic (1.45e-1)" "unprognostic (5.83e-3)" "unprognostic (1.34e-3)" "unprognostic (3.84e-1)" "potential prognostic unfavorable (6.84e-5)" "unprognostic (4.88e-2)" "unprognostic (2.81e-1)" "unprognostic (1.01e-1)" "unprognostic (1.46e-1)" "unprognostic (1.30e-1)" "unprognostic (1.34e-2)" "potential prognostic unfavorable (5.00e-4)" "unprognostic (2.61e-2)" "unprognostic (2.51e-2)" "unprognostic (1.27e-2)" "unprognostic (4.96e-2)" "unprognostic (4.33e-2)" "unprognostic (2.35e-1)" "potential prognostic unfavorable (2.11e-5)" "unprognostic (2.59e-1)" "unprognostic (4.94e-2)" "unprognostic (2.03e-2)" MATN4 ENSG00000124159 "Matrilin 4" O95460 20 45293445-45308529 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "pancreas: 23.4" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 4.7;Breast secretory cells: 4.6;Differentiating spermatogonia: 5.4;Early primary spermatocytes: 4.1;Endometrial luminal cells: 4.3;Fibroblasts: 6.7;Lacrimal acinar cells: 5.4;Oligodendrocyte progenitor cells: 4.7;Pancreatic acinar cells: 4.5;Salivary acinar cells: 5.8;Salivary basal cells: 5.8;Schwann cells: 4.6" "Cell type enhanced" "Detected in some" "committed oligodendrocyte precursor: 4.8;oligodendrocyte precursor cell: 5.3;upper-layer intratelencephalic: 5.3" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Minor Salivary Gland - Minor salivary glandular cells, Skin - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Secreted to extracellular matrix" "No annotated function" NA NA 11000 "Cluster 8: Pancreas - Proteolysis" "Cluster 59: Leukemia - T-cell receptor" "Cluster 108: Fibroblasts - ECM organization" 1 "unprognostic (4.67e-1)" "unprognostic (1.12e-1)" MATR3 "KIAA0723, MGC9105, MPD2, VCPDM" ENSG00000015479 "Matrin 3" P43243 5 139293674-139331677 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity" RNA-binding "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Corticotrophs: 3.3;Fallopian secretory cells: 3.6;Fallopian tube ciliated cells: 3.4;Medullary thymic epithelial cells: 4.8;Megakaryocyte progenitors: 3.7;Megakaryocytes: 12.4" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033552, HPA036564, HPA036565" Supported Approved Nucleoplasm NA NA 270000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 65: Brain - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 47: Platelets - Hemostasis" 134 Nucleoplasm "CAB033552: , HPA036564: , HPA036565: " "unprognostic (3.21e-2)" "unprognostic (8.09e-2)" "unprognostic (7.66e-2)" "unprognostic (1.75e-2)" "unprognostic (1.86e-1)" "unprognostic (1.14e-1)" "unprognostic (8.86e-3)" "unprognostic (2.36e-1)" "unprognostic (1.93e-2)" "validated prognostic favorable (1.20e-9)" "validated prognostic favorable (6.43e-4)" "unprognostic (2.20e-1)" "potential prognostic unfavorable (5.82e-4)" "unprognostic (3.17e-1)" "unprognostic (6.68e-2)" "unprognostic (6.69e-2)" "unprognostic (2.11e-1)" "unprognostic (5.70e-2)" "unprognostic (4.54e-3)" "unprognostic (1.35e-1)" "unprognostic (2.16e-2)" "unprognostic (2.79e-2)" "unprognostic (3.89e-2)" "unprognostic (1.89e-1)" "unprognostic (1.27e-1)" "unprognostic (2.66e-1)" "unprognostic (2.73e-1)" "unprognostic (1.11e-1)" "unprognostic (4.63e-2)" MATR3 ENSG00000280987 "Matrin 3" 5 139273752-139331671 "Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 15.5;Megakaryocyte progenitors: 6.8;Megakaryocyte-Erythroid progenitors: 8.2;Myonuclei: 22.7;Thymic myoid cells: 6.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "HPA036564, HPA036565" Supported Approved Nucleoplasm NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 61: Non-specific - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 55: Myocytes - Oxidative muscle function" 138 Nucleoplasm "HPA036564: , HPA036565: " "unprognostic (1.38e-1)" "unprognostic (2.37e-1)" "unprognostic (5.23e-2)" "unprognostic (4.59e-2)" "unprognostic (6.58e-2)" "unprognostic (2.07e-2)" "unprognostic (1.40e-1)" "unprognostic (4.15e-1)" "unprognostic (5.07e-3)" "potential prognostic favorable (1.14e-4)" "potential prognostic unfavorable (9.69e-5)" "unprognostic (7.73e-3)" "unprognostic (1.02e-3)" "unprognostic (2.60e-2)" "unprognostic (1.76e-2)" "unprognostic (3.15e-2)" "unprognostic (1.08e-2)" "unprognostic (2.11e-2)" "unprognostic (2.40e-2)" "unprognostic (7.69e-3)" "unprognostic (8.78e-2)" "potential prognostic favorable (8.90e-4)" "unprognostic (1.55e-1)" "unprognostic (4.95e-2)" "unprognostic (1.61e-1)" "unprognostic (3.57e-1)" "unprognostic (1.61e-2)" "unprognostic (9.61e-2)" MAU2 "KIAA0892, mau-2, MAU2L, MGC75361, SCC4" ENSG00000129933 "MAU2 sister chromatid cohesion factor" Q9Y6X3 19 19320829-19358754 "Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 189.5;Neutrophils: 149.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pancreas - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059897 Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 24: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 23: Non-specific - Transcription" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 20 Nucleoplasm "Nuclear bodies" "HPA059897: " "unprognostic (6.47e-2)" "unprognostic (2.15e-2)" "unprognostic (9.82e-2)" "unprognostic (5.29e-2)" "unprognostic (1.06e-2)" "unprognostic (3.61e-2)" "unprognostic (9.14e-3)" "potential prognostic favorable (3.35e-4)" "unprognostic (1.01e-2)" "potential prognostic favorable (3.61e-4)" "unprognostic (1.99e-2)" "unprognostic (6.36e-2)" "unprognostic (2.97e-3)" "unprognostic (4.43e-1)" "unprognostic (1.63e-2)" "unprognostic (2.82e-2)" "unprognostic (2.18e-1)" "unprognostic (1.11e-3)" "unprognostic (5.66e-2)" "unprognostic (3.00e-1)" "unprognostic (6.17e-2)" "unprognostic (8.11e-3)" "unprognostic (1.21e-1)" "unprognostic (7.65e-2)" "potential prognostic favorable (4.04e-4)" "potential prognostic unfavorable (2.32e-4)" "unprognostic (9.58e-2)" "unprognostic (7.23e-2)" "unprognostic (3.54e-2)" "unprognostic (1.67e-1)" MAVS "Cardif, IPS-1, KIAA1271, VISA" ENSG00000088888 "Mitochondrial antiviral signaling protein" Q7Z434 20 3846799-3876123 "Predicted membrane proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Platelets: 182.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009187, HPA049850, HPA053524" Enhanced Enhanced Mitochondria NA NA 200000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 30: White matter - Myelination" "Cluster 62: Non-specific - Plasma proteins" "Cluster 47: Platelets - Hemostasis" 115 Mitochondria "CAB009187: , HPA049850: , HPA053524: " "unprognostic (4.81e-2)" "unprognostic (7.64e-3)" "unprognostic (1.62e-1)" "unprognostic (5.98e-3)" "unprognostic (1.02e-1)" "unprognostic (6.81e-2)" "unprognostic (1.83e-1)" "unprognostic (4.16e-2)" "unprognostic (2.88e-1)" "unprognostic (8.39e-3)" "unprognostic (2.23e-3)" "potential prognostic favorable (7.39e-4)" "potential prognostic favorable (5.79e-4)" "unprognostic (1.65e-3)" "unprognostic (3.82e-3)" "unprognostic (1.12e-1)" "unprognostic (4.50e-2)" "potential prognostic unfavorable (6.38e-4)" "unprognostic (2.33e-1)" "unprognostic (9.05e-3)" "unprognostic (3.79e-2)" "unprognostic (5.41e-3)" "unprognostic (1.81e-2)" "unprognostic (1.01e-1)" "unprognostic (1.05e-2)" "unprognostic (8.53e-2)" "unprognostic (1.50e-1)" "unprognostic (1.98e-1)" "unprognostic (4.63e-1)" "unprognostic (1.50e-1)" "unprognostic (8.62e-2)" MAX "bHLHd4, bHLHd5, bHLHd6, bHLHd7, bHLHd8" ENSG00000125952 "MYC associated factor X" P61244 14 65006174-65102695 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 764.2;Platelets: 1720.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000328, HPA003474" Supported Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 25: Non-specific - Transcription" "Cluster 49: HMC-1 - Innate immune response" "Cluster 47: Platelets - Hemostasis" 89 Nucleoplasm "Golgi apparatus" "CAB000328: , HPA003474: " "unprognostic (3.96e-2)" "unprognostic (6.81e-2)" "unprognostic (3.30e-1)" "unprognostic (4.07e-2)" "unprognostic (2.67e-1)" "potential prognostic unfavorable (4.18e-4)" "unprognostic (2.52e-1)" "unprognostic (1.08e-1)" "unprognostic (1.33e-1)" "unprognostic (1.08e-1)" "potential prognostic favorable (1.33e-5)" "unprognostic (2.95e-2)" "unprognostic (1.02e-2)" "unprognostic (1.99e-3)" "unprognostic (1.60e-1)" "unprognostic (2.90e-1)" "unprognostic (4.92e-2)" "unprognostic (2.31e-2)" "unprognostic (1.64e-1)" "unprognostic (1.13e-1)" "unprognostic (8.61e-2)" "unprognostic (1.02e-1)" "unprognostic (1.28e-1)" "unprognostic (8.54e-2)" "unprognostic (1.98e-1)" "unprognostic (1.48e-1)" "unprognostic (3.05e-1)" "unprognostic (1.53e-1)" "unprognostic (5.27e-2)" "unprognostic (3.43e-2)" "unprognostic (1.75e-2)" MAZ "Pur-1, ZF87, Zif87, ZNF801" ENSG00000103495 "MYC associated zinc finger protein" P56270 16 29806106-29811164 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 17.9;Loop of henle epithelial cells: 10.7;Megakaryocytes: 18.5;Papillary tip epithelial cells: 12.9;Platelets: 12.6;Podocytes: 13.9;Proximal tubule cells: 10.4;Renal collecting duct principal cells: 10.4;Tuft cells: 11.5" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048315, HPA059495, HPA065930" Approved Enhanced Nucleoplasm NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 51: Neurons - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 105: Non-specific - Mixed function" 9 Nucleoplasm "HPA048315: , HPA059495: , HPA065930: " "unprognostic (2.04e-1)" "unprognostic (1.72e-1)" "unprognostic (3.74e-2)" "unprognostic (2.32e-1)" "unprognostic (6.96e-2)" "unprognostic (3.21e-2)" "unprognostic (9.96e-2)" "unprognostic (6.15e-3)" "unprognostic (2.88e-1)" "unprognostic (2.62e-1)" "unprognostic (1.58e-1)" "unprognostic (1.24e-1)" "unprognostic (9.00e-2)" "validated prognostic unfavorable (4.92e-5)" "validated prognostic unfavorable (2.08e-4)" "unprognostic (2.63e-2)" "unprognostic (2.74e-3)" "unprognostic (4.82e-1)" "unprognostic (2.16e-2)" "unprognostic (1.91e-2)" "unprognostic (1.22e-2)" "unprognostic (3.09e-1)" "unprognostic (2.43e-3)" "unprognostic (1.03e-1)" "unprognostic (5.86e-2)" "unprognostic (6.32e-2)" "unprognostic (2.97e-1)" "unprognostic (1.73e-2)" "unprognostic (3.43e-1)" "potential prognostic unfavorable (9.58e-4)" "unprognostic (1.23e-1)" MB PVALB ENSG00000198125 Myoglobin P02144 22 35606764-35637951 "Candidate cardiovascular disease genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Transporters" "Oxygen transport, Transport" "Muscle protein, Oxidoreductase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 38 "heart muscle: 14050.6;skeletal muscle: 38156.8;tongue: 27139.2" "Group enriched" "Detected in many" 5 "Myonuclei: 613.9;Thymic myoid cells: 1472.5" "Cell type enhanced" "Detected in single" "mammillary body: 1.2" "Group enriched" "Detected in many" 5 "Breast Invasive Carcinoma (TCGA): 53.1;Head and Neck Squamous Cell Carcinoma (TCGA): 104.6;Prostate Adenocarcinoma (TCGA): 99.0" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 6 "NK-cell: 1.3" "Lineage enriched" "Detected in single" 6 "NK-cells: 1.3" "Cancer enhanced" "Detected in many" "breast cancer: 78.8;prostate cancer: 80.1" "Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Pituitary gland - Corticotropes, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in many" "CAB000060, HPA003123" Enhanced NA NA 73000000 "Cluster 14: Non-specific - Unknown function" "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 19: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 1 "CAB000060: , HPA003123: " "unprognostic (1.60e-1)" "unprognostic (4.64e-2)" "unprognostic (6.20e-2)" "unprognostic (3.31e-3)" "unprognostic (1.12e-2)" "unprognostic (1.15e-1)" "unprognostic (4.06e-1)" "unprognostic (5.21e-3)" "potential prognostic unfavorable (5.94e-5)" "unprognostic (1.61e-1)" "unprognostic (2.52e-3)" "unprognostic (8.05e-2)" "unprognostic (7.91e-2)" "unprognostic (1.50e-1)" "unprognostic (9.08e-2)" "unprognostic (6.94e-2)" "unprognostic (2.18e-2)" "unprognostic (2.57e-1)" "unprognostic (3.23e-3)" "potential prognostic unfavorable (5.43e-4)" "unprognostic (3.64e-2)" "unprognostic (2.33e-1)" "unprognostic (9.98e-3)" "unprognostic (1.06e-1)" "unprognostic (1.77e-1)" "potential prognostic unfavorable (5.60e-4)" "unprognostic (1.30e-1)" MB21D2 C3orf59 ENSG00000180611 "Mab-21 domain containing 2" Q8IYB1 3 192796815-192917856 "Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "cDC: 211.9;Cytotrophoblasts: 319.0;Endometrial luminal cells: 332.1;Macrophages: 176.5;Migrating cytotrophoblasts: 179.6;Syncytiotrophoblasts: 424.1;Thyrotrophs: 217.5;Urothelial cells: 234.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory CD4 T-cell: 4.2;T-reg: 3.9" "Lineage enriched" "Detected in single" 9 "T-cells: 4.2" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044026 Approved Approved Cytosol NA Yes "Cluster 6: T-cells - T-cell receptor" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 31: Non-specific - Transcription" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 82: Dendritic cells - Antigen presentation" 13 Cytosol "HPA044026: " "unprognostic (7.84e-2)" "unprognostic (3.31e-2)" "unprognostic (4.20e-2)" "unprognostic (5.80e-2)" "unprognostic (7.56e-2)" "unprognostic (1.57e-2)" "potential prognostic favorable (4.30e-4)" "unprognostic (4.60e-3)" "unprognostic (4.75e-2)" "potential prognostic favorable (2.13e-7)" "unprognostic (1.00e-2)" "unprognostic (4.87e-2)" "unprognostic (3.35e-1)" "unprognostic (1.01e-2)" "unprognostic (2.06e-1)" "unprognostic (3.27e-1)" "unprognostic (1.23e-1)" "unprognostic (2.04e-1)" "unprognostic (6.53e-2)" "unprognostic (3.44e-2)" "unprognostic (7.22e-2)" "unprognostic (1.43e-1)" "unprognostic (1.72e-1)" "unprognostic (4.15e-2)" "unprognostic (3.39e-2)" "unprognostic (9.48e-3)" "unprognostic (3.80e-1)" "unprognostic (1.55e-2)" "unprognostic (1.59e-1)" MBD1 "CXXC3, PCM1" ENSG00000141644 "Methyl-CpG binding domain protein 1" Q9UIS9 18 50266882-50281774 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 276.2;Late spermatids: 151.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009017, CAB036003, HPA068850" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 67: Testis - Mixed function" "Cluster 34: Non-specific - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 30 "Nucleoplasm, Vesicles" "CAB009017: , CAB036003: , HPA068850: " "unprognostic (1.74e-1)" "unprognostic (1.23e-2)" "unprognostic (2.19e-1)" "unprognostic (2.89e-2)" "unprognostic (2.67e-1)" "unprognostic (2.44e-1)" "unprognostic (3.00e-1)" "potential prognostic favorable (3.90e-5)" "unprognostic (1.29e-2)" "unprognostic (4.05e-2)" "validated prognostic favorable (5.56e-5)" "validated prognostic favorable (9.49e-4)" "unprognostic (3.90e-3)" "potential prognostic unfavorable (1.32e-4)" "unprognostic (4.60e-2)" "unprognostic (9.29e-2)" "unprognostic (4.40e-1)" "unprognostic (9.50e-2)" "unprognostic (6.86e-3)" "unprognostic (1.60e-1)" "unprognostic (8.63e-2)" "unprognostic (3.79e-2)" "unprognostic (5.11e-3)" "unprognostic (1.27e-3)" "unprognostic (1.44e-1)" "unprognostic (2.30e-1)" "unprognostic (3.27e-2)" "unprognostic (4.11e-2)" "unprognostic (2.46e-1)" "unprognostic (6.86e-2)" "unprognostic (2.60e-1)" MBD2 ENSG00000134046 "Methyl-CpG binding domain protein 2" Q9UBB5 18 54151606-54224669 "Cancer-related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ocular epithelial cells: 398.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 5.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037282, HPA067582, HPA067615" Approved Supported Nucleoplasm NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 39: Testis - Nuclear processes" "Cluster 37: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 100: Stratified epithelial cells - Barrier functions" 48 Nucleoplasm "CAB037282: , HPA067582: , HPA067615: " "unprognostic (2.23e-1)" "unprognostic (9.84e-2)" "unprognostic (3.27e-2)" "unprognostic (1.44e-1)" "unprognostic (1.73e-2)" "unprognostic (1.18e-1)" "unprognostic (1.10e-1)" "unprognostic (1.43e-1)" "unprognostic (2.53e-1)" "unprognostic (1.50e-2)" "validated prognostic favorable (1.60e-5)" "validated prognostic favorable (6.08e-4)" "unprognostic (3.48e-2)" "unprognostic (3.18e-3)" "unprognostic (5.65e-2)" "potential prognostic unfavorable (2.26e-6)" "unprognostic (6.34e-2)" "unprognostic (1.92e-2)" "unprognostic (3.53e-1)" "unprognostic (4.05e-2)" "unprognostic (3.60e-1)" "unprognostic (2.78e-2)" "unprognostic (3.36e-2)" "unprognostic (3.92e-3)" "unprognostic (2.14e-1)" "unprognostic (5.69e-2)" "unprognostic (6.03e-2)" "unprognostic (3.42e-1)" "unprognostic (9.70e-2)" "unprognostic (3.05e-1)" "unprognostic (9.41e-3)" MBD3 ENSG00000071655 "Methyl-CpG binding domain protein 3" O95983 19 1573596-1592865 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 149.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013265, HPA063189" Supported Supported Nucleoplasm NA NA "Cluster 2: Non-specific - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 23: Non-specific - Transcription" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 85 Nucleoplasm "CAB013265: , HPA063189: " "unprognostic (5.89e-2)" "unprognostic (7.59e-3)" "unprognostic (1.48e-1)" "potential prognostic unfavorable (7.90e-4)" "unprognostic (2.33e-1)" "unprognostic (3.41e-2)" "unprognostic (3.37e-1)" "unprognostic (9.40e-2)" "unprognostic (1.54e-2)" "unprognostic (1.29e-2)" "unprognostic (4.97e-2)" "unprognostic (6.44e-3)" "unprognostic (2.64e-1)" "potential prognostic unfavorable (3.79e-5)" "unprognostic (3.87e-3)" "unprognostic (4.65e-2)" "unprognostic (7.52e-2)" "unprognostic (5.10e-2)" "unprognostic (5.92e-2)" "unprognostic (1.37e-1)" "unprognostic (1.60e-2)" "potential prognostic favorable (3.31e-4)" "unprognostic (1.53e-1)" "unprognostic (7.46e-2)" "unprognostic (8.54e-2)" "unprognostic (1.59e-1)" "unprognostic (2.66e-1)" "unprognostic (1.84e-2)" "unprognostic (3.46e-2)" "unprognostic (2.17e-2)" "unprognostic (8.48e-2)" MBD3L1 MBD3L ENSG00000170948 "Methyl-CpG binding domain protein 3 like 1" Q8WWY6 19 8832377-8843340 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "testis: 25.7" "Group enriched" "Detected in some" 8 "Early spermatids: 369.4;Late primary spermatocytes: 249.9;Late spermatids: 168.8" "Low cell type specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "HPA043121, HPA046753" Supported NA NA "Cluster 47: Testis - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 56 "HPA043121: , HPA046753: " MBD3L2 ENSG00000230522 "Methyl-CpG binding domain protein 3 like 2" Q8NHZ7 19 7049321-7051735 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 8 "Testicular Germ Cell Tumor (TCGA): 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 4.5;Rhabdoid: 1.2" HPA051259 Uncertain Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 12: Bone cancer - Neuronal signaling" 17 "Nucleoplasm, Nucleoli" Cytosol "HPA051259: " "unprognostic (3.53e-1)" MBD3L2B ENSG00000196589 "Methyl-CpG binding domain protein 3 like 2B" A0A1B0GVZ6 19 7018969-7021432 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Bone cancer: 1.1" HPA051259 Uncertain Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 12: Bone cancer - Neuronal signaling" "Nucleoplasm, Nucleoli" Cytosol "HPA051259: " MBD3L3 ENSG00000182315 "Methyl-CpG binding domain protein 3 like 3" A6NE82 19 7056207-7069665 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Adipocytes: 2.6;Cardiomyocytes: 5.5;Colonocytes: 3.5;Early primary spermatocytes: 4.0;Enterocytes: 1.8;Epididymal clear cells: 2.0;Goblet cells: 1.6;Myosatellite cells: 2.3;Pancreatic acinar cells: 1.9;Retinal horizontal cells: 2.0;Thymocytes: 2.5;Undifferentiated spermatogonia: 3.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 122 "Bone cancer: 93.5" HPA051259 Uncertain Nucleoplasm,Nucleoli NA NA "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 65: Non-specific - Cell growth & division" 1 "Nucleoplasm, Nucleoli" "HPA051259: " MBD3L4 ENSG00000205718 "Methyl-CpG binding domain protein 3 like 4" A6NDZ8 19 7037749-7040179 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA051259 Uncertain Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 12: Bone cancer - Neuronal signaling" "Nucleoplasm, Nucleoli" Cytosol "HPA051259: " MBD3L5 ENSG00000237247 "Methyl-CpG binding domain protein 3 like 5" A6NJ08 19 7030578-7033011 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 20 "Bone cancer: 2.0" HPA051259 Uncertain Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 12: Bone cancer - Neuronal signaling" "Nucleoplasm, Nucleoli" Cytosol "HPA051259: " MBD4 MED1 ENSG00000129071 "Methyl-CpG binding domain 4, DNA glycosylase" O95243 3 129430947-129440179 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Hydrolase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002031 Supported Supported "Nuclear speckles" NA NA "Cluster 18: Non-specific - Translation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 55: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 11 "Nuclear speckles" "HPA002031: " "unprognostic (3.47e-1)" "unprognostic (1.72e-3)" "unprognostic (7.15e-3)" "unprognostic (2.11e-1)" "unprognostic (2.66e-2)" "unprognostic (1.32e-1)" "unprognostic (1.07e-2)" "unprognostic (2.30e-1)" "unprognostic (3.29e-2)" "unprognostic (1.08e-3)" "unprognostic (2.74e-2)" "unprognostic (1.59e-1)" "unprognostic (3.46e-1)" "unprognostic (3.81e-2)" "unprognostic (1.07e-1)" "unprognostic (2.12e-1)" "unprognostic (3.44e-2)" "unprognostic (6.19e-2)" "unprognostic (9.19e-2)" "unprognostic (1.00e-1)" "unprognostic (8.77e-3)" "unprognostic (1.46e-2)" "unprognostic (4.52e-2)" "unprognostic (3.15e-3)" "unprognostic (7.08e-2)" "unprognostic (3.03e-1)" "unprognostic (1.73e-1)" "unprognostic (1.09e-1)" "unprognostic (1.74e-1)" "unprognostic (3.03e-1)" "unprognostic (8.83e-2)" MBD5 "FLJ11113, KIAA1461" ENSG00000204406 "Methyl-CpG binding domain protein 5" Q9P267 2 148021011-148516971 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035964 Supported Nucleoplasm,Midbody Yes NA "Cluster 65: Brain - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 4 Nucleoplasm Midbody "HPA035964: " "unprognostic (9.06e-2)" "unprognostic (3.20e-2)" "unprognostic (1.65e-1)" "unprognostic (2.33e-2)" "unprognostic (1.86e-1)" "unprognostic (1.11e-1)" "unprognostic (9.43e-2)" "unprognostic (6.25e-2)" "unprognostic (3.21e-2)" "unprognostic (2.08e-1)" "potential prognostic favorable (6.39e-4)" "unprognostic (1.49e-3)" "unprognostic (4.50e-3)" "unprognostic (4.10e-1)" "unprognostic (3.34e-1)" "unprognostic (2.31e-1)" "unprognostic (9.01e-2)" "unprognostic (5.29e-2)" "unprognostic (1.48e-1)" "unprognostic (1.49e-3)" "unprognostic (9.64e-2)" "unprognostic (4.67e-3)" "unprognostic (7.23e-2)" "unprognostic (3.18e-1)" "unprognostic (1.05e-2)" "unprognostic (7.61e-2)" "unprognostic (1.44e-1)" "unprognostic (5.07e-2)" "unprognostic (2.58e-2)" "unprognostic (2.86e-1)" MBD6 KIAA1887 ENSG00000166987 "Methyl-CpG binding domain protein 6" Q96DN6 12 57520710-57530148 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 194.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 10 "neutrophil: 13.7" "Lineage enriched" "Detected in many" 10 "granulocytes: 13.7" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Prostate - Prostate basal glandular cells, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038948, HPA038949" Uncertain Enhanced Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 49: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 38: Non-specific - Transcription" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 5 Nucleoplasm "HPA038948: , HPA038949: " "unprognostic (9.50e-2)" "unprognostic (5.23e-2)" "unprognostic (3.23e-1)" "unprognostic (5.75e-2)" "unprognostic (1.43e-1)" "unprognostic (2.04e-2)" "unprognostic (2.52e-1)" "unprognostic (2.82e-1)" "unprognostic (2.05e-1)" "unprognostic (1.89e-1)" "unprognostic (6.84e-2)" "unprognostic (1.93e-1)" "unprognostic (2.55e-1)" "unprognostic (3.83e-3)" "unprognostic (1.59e-1)" "unprognostic (8.44e-2)" "unprognostic (8.14e-2)" "unprognostic (2.18e-1)" "unprognostic (6.11e-2)" "unprognostic (9.34e-2)" "unprognostic (1.57e-1)" "unprognostic (1.87e-1)" "unprognostic (1.18e-2)" "unprognostic (3.95e-2)" "unprognostic (3.76e-1)" "unprognostic (7.27e-2)" "unprognostic (2.13e-2)" "unprognostic (1.90e-1)" "unprognostic (3.34e-1)" "unprognostic (7.31e-3)" "unprognostic (3.23e-1)" MBIP ENSG00000151332 "MAP3K12 binding inhibitory protein 1" Q9NS73 14 36298564-36320637 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 176.3;Alveolar cells type 2: 422.3;Parietal cells: 153.8;Pituicytes/FSCs: 243.4;Transitional alveolar cells: 325.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Thyroid Carcinoma (TCGA): 105.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003388 Supported Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 11: T-cells - Unknown function" "Cluster 55: Breast - Lactation" "Cluster 31: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 81: Alveolar cells - Lung function" 49 Cytosol "Nucleoplasm, Nucleoli" "HPA003388: " "unprognostic (1.77e-1)" "unprognostic (5.00e-2)" "unprognostic (7.17e-3)" "unprognostic (1.08e-1)" "unprognostic (2.59e-1)" "unprognostic (3.72e-1)" "unprognostic (1.08e-1)" "unprognostic (8.79e-3)" "unprognostic (6.98e-2)" "unprognostic (2.90e-2)" "potential prognostic favorable (3.09e-4)" "unprognostic (1.72e-2)" "unprognostic (2.01e-1)" "unprognostic (1.24e-1)" "unprognostic (2.87e-2)" "potential prognostic favorable (2.09e-5)" "unprognostic (1.37e-1)" "unprognostic (3.07e-1)" "unprognostic (4.42e-2)" "unprognostic (1.74e-2)" "unprognostic (1.02e-1)" "unprognostic (1.57e-1)" "unprognostic (2.58e-1)" "unprognostic (1.91e-1)" "unprognostic (4.30e-2)" "unprognostic (3.19e-2)" "unprognostic (5.81e-2)" "unprognostic (1.48e-1)" "unprognostic (4.43e-1)" "unprognostic (3.33e-2)" "unprognostic (2.09e-1)" MBL2 "COLEC1, MBL, MBP, MBP-C, MBP1" ENSG00000165471 "Mannose binding lectin 2" P11226 10 52765380-52772784 "Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement activation lectin pathway, Complement pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 2628 "liver: 262.8" "Cell type enriched" "Detected in some" 290 "Hepatocytes: 297.6" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 240 "Liver Hepatocellular Carcinoma (TCGA): 27.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "liver cancer: 1.0" "Not detected" "Not detected" "Region enriched" "Detected in single" 13 "basal ganglia: 1.3" "HPA002027, CAB016782" Enhanced "Secreted to blood" "Complement pathway" NA NA 1220000000 780000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 18: Liver cancer - Metabolism" "Cluster 93: Hepatocytes - Bile production & excretion" 27 "CAB016782: , HPA002027: " "unprognostic (1.50e-2)" "potential prognostic favorable (2.52e-7)" MBLAC1 MGC49416 ENSG00000214309 "Metallo-beta-lactamase domain containing 1" A4D2B0 7 100126785-100128495 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 24.3;Epididymal efferent duct absorptive cells: 12.6;Esophageal apical cells: 31.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071574 Uncertain NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 84: Apical squamous epithelium - Cornification" 1 "HPA071574: " "unprognostic (1.05e-1)" "unprognostic (1.68e-2)" "unprognostic (6.95e-3)" "unprognostic (8.78e-2)" "unprognostic (3.18e-1)" "unprognostic (4.26e-3)" "unprognostic (1.31e-2)" "unprognostic (2.41e-2)" "potential prognostic favorable (1.69e-4)" "unprognostic (3.88e-1)" "unprognostic (3.29e-1)" "unprognostic (1.07e-1)" "potential prognostic favorable (6.31e-8)" "unprognostic (5.87e-2)" "unprognostic (1.26e-2)" "unprognostic (6.59e-2)" "unprognostic (7.38e-2)" "unprognostic (8.76e-2)" "unprognostic (1.77e-1)" "potential prognostic favorable (3.73e-4)" "unprognostic (2.66e-1)" "unprognostic (8.08e-2)" "unprognostic (1.15e-1)" "unprognostic (1.77e-1)" "unprognostic (8.17e-2)" "unprognostic (1.59e-1)" "unprognostic (5.19e-2)" "unprognostic (2.18e-1)" "unprognostic (1.85e-1)" MBLAC2 "DKFZp686P15118, MGC46734" ENSG00000176055 "Metallo-beta-lactamase domain containing 2" Q68D91 5 90458209-90474771 "Enzymes, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 39.3;Corticotrophs: 29.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037757, HPA037758" Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 24: Non-specific - Transcription" "Cluster 65: Brain - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 98: Neurons - Neurotransmission & signaling" 3 Mitochondria Nucleoplasm "HPA037757: , HPA037758: " "unprognostic (8.12e-2)" "unprognostic (1.09e-1)" "unprognostic (2.00e-1)" "unprognostic (1.57e-1)" "unprognostic (2.85e-1)" "unprognostic (1.95e-1)" "unprognostic (1.56e-1)" "unprognostic (2.65e-1)" "unprognostic (9.55e-3)" "unprognostic (5.71e-3)" "potential prognostic favorable (6.77e-8)" "unprognostic (1.11e-1)" "unprognostic (5.96e-2)" "unprognostic (2.78e-2)" "unprognostic (4.51e-2)" "unprognostic (1.50e-1)" "unprognostic (3.28e-1)" "unprognostic (2.46e-1)" "unprognostic (4.33e-3)" "unprognostic (6.40e-2)" "unprognostic (3.87e-2)" "unprognostic (2.74e-1)" "unprognostic (1.01e-3)" "unprognostic (5.72e-2)" "unprognostic (3.81e-2)" "unprognostic (4.02e-2)" "unprognostic (1.72e-1)" "unprognostic (1.09e-1)" "unprognostic (1.49e-1)" MBNL1 "EXP, EXP35, EXP40, EXP42, KIAA0428, MBNL" ENSG00000152601 "Muscleblind like splicing regulator 1" Q9NR56 3 152243828-152465780 "Disease related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hematopoietic stem cells: 2628.0;Monocyte progenitors: 3082.1;Myonuclei: 4764.8;Neutrophil progenitors: 3513.4;Neutrophils: 5223.1;Thymic myoid cells: 2413.3" "Cell type enhanced" "Detected in all" "leukocyte: 3652.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016398, HPA035098" Enhanced Enhanced Nucleoplasm,Cytosol NA NA 10000 "Cluster 35: Neutrophils - Protein binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 24: Neutrophils - Innate immunity signal integration" 112 Nucleoplasm Cytosol "CAB016398: , HPA035098: " "unprognostic (4.81e-2)" "unprognostic (5.49e-2)" "unprognostic (4.31e-2)" "unprognostic (1.60e-1)" "unprognostic (2.96e-1)" "unprognostic (8.44e-2)" "unprognostic (8.31e-2)" "unprognostic (6.49e-2)" "unprognostic (1.84e-2)" "unprognostic (6.64e-3)" "potential prognostic favorable (3.62e-5)" "unprognostic (5.97e-2)" "unprognostic (6.24e-2)" "unprognostic (2.10e-2)" "unprognostic (1.03e-1)" "unprognostic (2.52e-1)" "unprognostic (9.12e-2)" "unprognostic (5.52e-2)" "unprognostic (2.02e-1)" "unprognostic (8.26e-2)" "unprognostic (2.18e-2)" "unprognostic (2.05e-2)" "unprognostic (1.74e-1)" "unprognostic (7.87e-2)" "unprognostic (2.16e-1)" "unprognostic (3.37e-3)" "unprognostic (1.16e-1)" "unprognostic (3.24e-2)" "unprognostic (1.80e-1)" "unprognostic (1.95e-2)" "unprognostic (1.15e-1)" MBNL2 "MBLL, MBLL39" ENSG00000139793 "Muscleblind like splicing regulator 2" Q5VZF2 13 97221434-97394120 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adrenal cortex cells: 912.3;Pancreatic acinar cells: 1251.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062685 Supported Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 76: Non-specific - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 44: Plasma cells - Antibody production & secretion" 1 Nucleoplasm "HPA062685: " "unprognostic (1.04e-2)" "unprognostic (6.00e-2)" "unprognostic (4.21e-2)" "unprognostic (5.76e-2)" "unprognostic (1.44e-1)" "potential prognostic unfavorable (6.40e-5)" "unprognostic (3.35e-1)" "unprognostic (6.12e-2)" "unprognostic (2.07e-1)" "unprognostic (2.79e-1)" "potential prognostic favorable (2.41e-7)" "unprognostic (1.03e-3)" "unprognostic (8.28e-2)" "unprognostic (2.97e-1)" "unprognostic (1.88e-3)" "unprognostic (3.19e-1)" "unprognostic (9.29e-2)" "potential prognostic unfavorable (1.79e-5)" "unprognostic (1.57e-2)" "unprognostic (1.24e-2)" "unprognostic (5.58e-3)" "potential prognostic unfavorable (1.92e-4)" "unprognostic (9.06e-3)" "unprognostic (1.42e-1)" "unprognostic (4.88e-1)" "unprognostic (1.34e-2)" "unprognostic (7.18e-2)" "unprognostic (4.00e-2)" "unprognostic (5.80e-2)" "unprognostic (4.94e-2)" "unprognostic (1.14e-1)" MBNL3 "CHCR, FLJ11316, MBLX39, MBXL" ENSG00000076770 "Muscleblind like splicing regulator 3" Q9NUK0 X 132369320-132489968 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 54.8;placenta: 153.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 472.5;Migrating cytotrophoblasts: 238.1;Sertoli cells: 201.7;Syncytiotrophoblasts: 448.4" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 78.1;leukocyte: 109.1" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 24.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "liver cancer: 40.1" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Testis - Sertoli cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA001584, HPA001793" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 32: Basophils - Transcription" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 21: Non-specific - Metabolism" "Cluster 18: Liver cancer - Metabolism" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 1 Nucleoplasm Cytosol "HPA001584: , HPA001793: " "unprognostic (3.70e-2)" "unprognostic (6.42e-2)" "unprognostic (1.88e-1)" "unprognostic (2.61e-2)" "unprognostic (1.63e-1)" "unprognostic (1.29e-1)" "unprognostic (3.65e-1)" "unprognostic (1.71e-2)" "unprognostic (1.11e-2)" "potential prognostic unfavorable (1.04e-5)" "unprognostic (5.60e-3)" "unprognostic (7.48e-2)" "unprognostic (2.14e-2)" "unprognostic (1.07e-1)" "unprognostic (8.98e-2)" "unprognostic (8.36e-2)" "unprognostic (2.35e-1)" "unprognostic (3.57e-1)" "unprognostic (3.01e-1)" "unprognostic (7.52e-2)" "unprognostic (2.15e-1)" "unprognostic (4.59e-3)" "unprognostic (3.69e-3)" "unprognostic (2.00e-1)" "unprognostic (1.48e-3)" "unprognostic (7.16e-3)" "unprognostic (6.93e-2)" "unprognostic (1.75e-1)" "unprognostic (2.07e-1)" "unprognostic (9.24e-2)" "potential prognostic unfavorable (4.86e-4)" MBOAT1 "dJ434O11.1, LPEAT1, LPLAT14, MGC44669, OACT1" ENSG00000172197 "Membrane bound O-acyltransferase domain containing 1" Q6ZNC8 6 20099684-20212469 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 162.3;Renal collecting duct intercalated cells: 179.6;Respiratory deuterosomal cells: 170.0;Salivary ionocytes: 191.4" "Cell type enhanced" "Detected in many" "fibroblast: 58.2;leukocyte: 64.8;oligodendrocyte: 105.7;pericyte: 61.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 77: Intestine - Digestion" "Cluster 30: White matter - Myelination" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 48: Neutrophils - Phagocytosis & degranulation" "unprognostic (5.84e-2)" "unprognostic (1.28e-2)" "unprognostic (8.19e-2)" "unprognostic (1.96e-3)" "unprognostic (2.86e-2)" "unprognostic (1.84e-1)" "unprognostic (3.24e-2)" "unprognostic (5.86e-2)" "unprognostic (1.01e-1)" "unprognostic (6.11e-2)" "unprognostic (8.76e-2)" "unprognostic (6.47e-2)" "unprognostic (1.71e-2)" "unprognostic (4.17e-3)" "unprognostic (1.41e-1)" "unprognostic (1.12e-2)" "unprognostic (2.07e-3)" "unprognostic (7.35e-2)" "unprognostic (6.04e-2)" "potential prognostic favorable (9.15e-7)" "unprognostic (2.39e-2)" "unprognostic (2.44e-3)" "unprognostic (1.20e-1)" "unprognostic (4.25e-2)" "unprognostic (1.31e-2)" "unprognostic (6.28e-2)" "unprognostic (9.49e-3)" "unprognostic (2.27e-2)" "unprognostic (2.15e-1)" "unprognostic (5.44e-2)" "unprognostic (1.25e-1)" MBOAT2 "FLJ14415, FLJ90298, LPLAT13, OACT2" ENSG00000143797 "Membrane bound O-acyltransferase domain containing 2" Q6ZWT7 2 8852690-9003709 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bergmann glia: 486.0;Choroid plexus epithelial cells: 441.6;Conjunctival goblet cells: 412.6;Erythrocyte progenitors: 618.9;Esophageal apical cells: 1372.2;Esophageal suprabasal cells: 523.1;Neutrophil progenitors: 666.9;Neutrophils: 645.1;Retinal horizontal cells: 418.7;Salivary duct cells: 712.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "basophil: 4.7;eosinophil: 1.7;neutrophil: 4.0" "Lineage enriched" "Detected in single" 10 "granulocytes: 4.7" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Liver - Hepatic stellate cells, Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Prostate glandular cells, Spleen - Neutrophils_2, Stomach - Gastric mucous cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014836 Uncertain Approved Vesicles NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 73: Brain - Neuronal signaling" "Cluster 21: Non-specific - Metabolism" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 37: Neutrophil progenitors - Granulopoiesis" Vesicles "HPA014836: " "unprognostic (3.08e-3)" "unprognostic (4.37e-1)" "unprognostic (9.44e-2)" "potential prognostic unfavorable (2.05e-4)" "unprognostic (2.10e-1)" "potential prognostic unfavorable (3.77e-4)" "unprognostic (2.39e-1)" "unprognostic (4.22e-2)" "unprognostic (5.41e-2)" "unprognostic (9.81e-2)" "unprognostic (4.96e-3)" "unprognostic (1.66e-2)" "unprognostic (3.60e-1)" "unprognostic (2.82e-3)" "unprognostic (2.17e-3)" "potential prognostic unfavorable (2.29e-5)" "unprognostic (4.73e-2)" "unprognostic (1.17e-1)" "unprognostic (3.40e-1)" "unprognostic (4.77e-3)" "unprognostic (7.52e-3)" "unprognostic (1.78e-2)" "unprognostic (3.88e-1)" "unprognostic (1.28e-1)" "unprognostic (4.76e-2)" "unprognostic (2.57e-1)" "unprognostic (1.68e-1)" "unprognostic (1.64e-1)" "unprognostic (1.51e-1)" "unprognostic (5.49e-3)" MBOAT4 "FKSG89, GOAT, OACT4" ENSG00000177669 "Membrane bound O-acyltransferase domain containing 4" Q96T53 8 30131671-30144665 "Metabolic proteins, Predicted membrane proteins, Transporters" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "pancreas: 3.3;stomach 1: 3.5" "Group enriched" "Detected in some" 4 "Cholangiocytes: 35.3;Epicardial cells: 18.2;Neuroendocrine cells: 41.7;Pancreatic islet cells: 40.8" "Cell type enhanced" "Detected in some" "Bergmann glia: 2.3;leukocyte: 2.3" "Cancer enhanced" "Detected in single" "Pancreatic Adenocarcinoma (TCGA): 2.5" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Stomach - Gastric enteroendocrine cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA044509 Supported "Golgi apparatus" NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 18: Liver cancer - Metabolism" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" "Golgi apparatus" "HPA044509: " "unprognostic (1.95e-3)" "unprognostic (1.45e-1)" "unprognostic (1.28e-1)" "unprognostic (7.60e-2)" MBOAT7 "BB1, hMBOA-7, LENG4, LPIAT1, LPLAT, LPLAT11" ENSG00000125505 "Membrane bound O-acyltransferase domain containing 7" Q96N66 19 54173412-54189882 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 127.7" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 31.9;Brain inhibitory neurons: 30.1;Ependymal cells: 33.7;Neutrophils: 67.9;Other brain neurons: 53.4;Papillary tip epithelial cells: 62.4;Podocytes: 23.7;Renal collecting duct principal cells: 39.8;Renal connecting tubule cells: 29.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 9 "basophil: 157.4;eosinophil: 265.9;neutrophil: 239.0" "Lineage enriched" "Detected in all" 11 "granulocytes: 265.9" "Low cancer specificity" "Detected in all" "Spleen - Neutrophils_2, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055967 Approved Approved Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 1: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 10 Cytosol "HPA055967: " "unprognostic (1.19e-1)" "unprognostic (1.16e-2)" "unprognostic (2.03e-1)" "unprognostic (3.23e-3)" "unprognostic (6.85e-2)" "unprognostic (5.51e-2)" "unprognostic (3.34e-1)" "unprognostic (5.93e-3)" "unprognostic (1.17e-1)" "unprognostic (4.81e-3)" "potential prognostic unfavorable (3.15e-6)" "unprognostic (8.89e-3)" "unprognostic (1.06e-1)" "potential prognostic unfavorable (4.59e-4)" "unprognostic (6.06e-3)" "unprognostic (1.30e-2)" "unprognostic (5.33e-2)" "unprognostic (4.61e-2)" "unprognostic (3.46e-1)" "unprognostic (1.59e-2)" "unprognostic (7.41e-2)" "unprognostic (5.64e-2)" "unprognostic (9.83e-3)" "unprognostic (1.58e-1)" "unprognostic (1.76e-1)" "unprognostic (2.32e-2)" "unprognostic (2.24e-1)" "unprognostic (1.09e-1)" "unprognostic (1.32e-1)" "unprognostic (8.65e-3)" "unprognostic (2.26e-1)" MBP ENSG00000197971 "Myelin basic protein" P02686 18 76978827-77133683 "Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Autoimmune encephalomyelitis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 32 "brain: 89103.1" "Group enriched" "Detected in many" 4 "Neutrophils: 1795.8;Oligodendrocytes: 4147.7" "Group enriched" "Detected in all" 6 "committed oligodendrocyte precursor: 2124.2;oligodendrocyte: 5605.9" "Group enriched" "Detected in all" 13 "Glioblastoma Multiforme (TCGA): 706.6;Skin Cutaneous Melanoma (TCGA): 298.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in many" 7 "skin cancer: 227.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002300, HPA049222, HPA064368" Enhanced Supported Approved "Plasma membrane" NA NA 650000 "Cluster 21: Neutrophils - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 80: Oligodendrocytes - Myelination" 23 "Plasma membrane" "CAB002300: , HPA049222: , HPA064368: " "unprognostic (9.02e-2)" "unprognostic (1.58e-1)" "unprognostic (1.57e-1)" "unprognostic (1.94e-1)" "unprognostic (1.11e-1)" "unprognostic (1.66e-1)" "unprognostic (3.88e-2)" "unprognostic (3.98e-1)" "unprognostic (9.31e-2)" "unprognostic (2.65e-1)" "potential prognostic favorable (5.63e-10)" "unprognostic (5.01e-3)" "unprognostic (2.78e-3)" "unprognostic (1.19e-1)" "unprognostic (1.40e-1)" "unprognostic (9.94e-2)" "unprognostic (1.12e-1)" "unprognostic (3.05e-2)" "unprognostic (1.66e-1)" "unprognostic (4.05e-2)" "unprognostic (6.41e-2)" "unprognostic (2.82e-2)" "unprognostic (1.25e-1)" "unprognostic (2.97e-1)" "unprognostic (5.40e-2)" "unprognostic (3.58e-2)" "unprognostic (3.50e-1)" "unprognostic (9.15e-2)" "unprognostic (3.33e-2)" "unprognostic (3.16e-2)" "unprognostic (1.82e-1)" MBTD1 "FLJ20055, SA49P01" ENSG00000011258 "Mbt domain containing 1" Q05BQ5 17 51177425-51260163 "Disease related genes, Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.6" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.6" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021876 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 39: Testis - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 7: Non-specific - Transcription" 44 Nucleoplasm Cytosol "HPA021876: " "unprognostic (7.62e-2)" "unprognostic (3.14e-1)" "unprognostic (1.64e-1)" "unprognostic (1.33e-1)" "unprognostic (1.76e-1)" "unprognostic (3.61e-2)" "unprognostic (3.60e-2)" "unprognostic (6.40e-3)" "unprognostic (1.15e-2)" "unprognostic (1.39e-2)" "unprognostic (3.88e-3)" "unprognostic (1.71e-3)" "unprognostic (8.96e-2)" "unprognostic (1.74e-1)" "unprognostic (1.46e-1)" "unprognostic (2.28e-1)" "unprognostic (2.08e-1)" "unprognostic (5.37e-2)" "unprognostic (1.68e-3)" "unprognostic (6.58e-2)" "potential prognostic unfavorable (3.62e-4)" "unprognostic (1.26e-1)" "unprognostic (5.93e-2)" "unprognostic (3.21e-2)" "potential prognostic favorable (1.12e-4)" "unprognostic (7.64e-3)" "unprognostic (1.18e-1)" "unprognostic (1.09e-1)" "unprognostic (2.78e-1)" "unprognostic (1.41e-1)" "unprognostic (1.90e-1)" MBTPS1 "KIAA0091, PCSK8, S1P, SKI-1" ENSG00000140943 "Membrane bound transcription factor peptidase, site 1" Q14703 16 84053761-84116942 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Hydrolase, Protease, Serine protease" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 389.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056109 Supported NA NA 6600 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 42: Retina - Visual perception" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 79: Photoreceptor cells - Phototransduction" 26 "HPA056109: " "unprognostic (1.46e-1)" "unprognostic (6.94e-2)" "unprognostic (8.12e-3)" "unprognostic (1.13e-2)" "unprognostic (2.16e-1)" "unprognostic (1.31e-1)" "unprognostic (7.01e-2)" "unprognostic (4.42e-3)" "unprognostic (4.52e-2)" "unprognostic (5.86e-2)" "potential prognostic favorable (1.93e-8)" "unprognostic (3.25e-2)" "unprognostic (6.24e-2)" "unprognostic (5.08e-2)" "unprognostic (1.28e-1)" "unprognostic (3.47e-1)" "unprognostic (9.36e-2)" "unprognostic (7.28e-3)" "unprognostic (2.02e-1)" "unprognostic (1.43e-1)" "unprognostic (1.91e-2)" "unprognostic (7.67e-2)" "unprognostic (5.56e-2)" "unprognostic (1.89e-1)" "unprognostic (9.17e-2)" "unprognostic (1.62e-1)" "unprognostic (1.90e-1)" "unprognostic (8.85e-2)" "unprognostic (2.81e-1)" "unprognostic (2.41e-3)" "unprognostic (4.02e-1)" MBTPS2 "KFSD, S2P" ENSG00000012174 "Membrane bound transcription factor peptidase, site 2" O43462 X 21839617-21885423 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Hydrolase, Metalloprotease, Protease" "Disease variant, Ichthyosis, Osteogenesis imperfecta, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 78.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "HPA005494, CAB009486" Approved Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 28: Liver & Adrenal gland - Secretion" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 36: Non-specific - mRNA processing" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 1 "Nucleoplasm, Mitochondria, Cytosol" "CAB009486: , HPA005494: " "unprognostic (3.45e-1)" "unprognostic (1.05e-2)" "unprognostic (2.14e-1)" "unprognostic (2.01e-1)" "unprognostic (9.30e-2)" "unprognostic (1.36e-1)" "unprognostic (1.59e-1)" "unprognostic (7.18e-2)" "unprognostic (1.71e-1)" "unprognostic (1.96e-2)" "potential prognostic favorable (1.63e-5)" "unprognostic (2.31e-2)" "unprognostic (6.46e-3)" "unprognostic (9.60e-2)" "unprognostic (7.54e-2)" "potential prognostic unfavorable (3.40e-4)" "unprognostic (2.44e-3)" "unprognostic (1.11e-1)" "unprognostic (1.10e-1)" "unprognostic (1.04e-1)" "potential prognostic unfavorable (6.29e-4)" "unprognostic (1.36e-1)" "unprognostic (1.69e-1)" "unprognostic (1.84e-1)" "unprognostic (2.23e-1)" "unprognostic (4.83e-3)" "unprognostic (1.88e-1)" "unprognostic (5.39e-2)" "unprognostic (1.61e-1)" "unprognostic (2.46e-1)" "unprognostic (3.02e-1)" MC1R MSH-R ENSG00000258839 "Melanocortin 1 receptor" Q01726 16 89912119-89920973 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 31.2;testis: 29.6" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 3.3;Brain inhibitory neurons: 4.2;Distal convoluted tubule cells: 6.9;Foveolar cells: 3.4;Loop of henle epithelial cells: 5.3;Medullary thymic epithelial cells: 2.4;Mucous neck cells: 2.7;Other brain neurons: 3.5;Papillary tip epithelial cells: 2.9;Podocytes: 5.9;Proximal tubule cells: 4.1;Renal collecting duct intercalated cells: 9.4;Renal collecting duct principal cells: 4.3;Renal connecting tubule cells: 6.8" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in all" 8 "Skin Cutaneous Melanoma (TCGA): 81.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "skin cancer: 49.6" "Minor Salivary Gland - Minor salivary glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 64: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 102: Non-specific - Mixed function" 2 "unprognostic (2.83e-2)" "unprognostic (1.64e-1)" "unprognostic (2.39e-1)" "unprognostic (3.26e-2)" "unprognostic (4.66e-3)" "unprognostic (8.15e-2)" "unprognostic (5.34e-2)" "unprognostic (2.90e-3)" "unprognostic (1.60e-1)" "unprognostic (3.13e-1)" "validated prognostic unfavorable (3.06e-12)" "validated prognostic unfavorable (4.39e-4)" "unprognostic (2.34e-3)" "unprognostic (1.87e-1)" "unprognostic (5.16e-3)" "potential prognostic unfavorable (1.47e-4)" "unprognostic (9.81e-2)" "unprognostic (2.03e-1)" "unprognostic (2.05e-1)" "unprognostic (2.48e-2)" "unprognostic (7.17e-2)" "unprognostic (1.03e-2)" "unprognostic (1.37e-3)" "unprognostic (1.10e-1)" "unprognostic (1.21e-3)" "unprognostic (1.50e-1)" "unprognostic (3.77e-2)" "unprognostic (1.84e-2)" "unprognostic (7.99e-2)" "unprognostic (1.66e-2)" "unprognostic (8.42e-2)" MC2R ACTHR ENSG00000185231 "Melanocortin 2 receptor" Q01718 18 13882044-13915707 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 30 "adrenal gland: 50.6" "Cell type enriched" "Detected in some" 8 "Adrenal cortex cells: 247.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adrenal gland - Adrenal cortex cells, Pituitary gland - Gonadotropes" "Not detected" "Not detected" "Not detected" "Not detected" HPA079148 Enhanced NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 56: Non-specific - Sensory perception" "Cluster 18: Adrenal cortex cells - Steroidogensis" 4 "HPA079148: " MC3R MC3 ENSG00000124089 "Melanocortin 3 receptor" P41968 20 56248732-56249815 "G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "Biological rhythms" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 12 "brain: 1.3" "Cell type enhanced" "Detected in single" "Early spermatids: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in many" 10 "hypothalamus: 31.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "basal ganglia: 4.8;hypothalamus: 4.5;thalamus: 1.3" "Group enriched" "Detected in some" 5 "basal ganglia: 4.2;hypothalamus: 2.8;thalamus: 3.3" HPA074739 Uncertain NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 98: Neurons - Neurotransmission & signaling" "HPA074739: " MC4R ENSG00000166603 "Melanocortin 4 receptor" P32245 18 60371062-60372775 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 3.5;fallopian tube: 2.9;retina: 3.6" "Group enriched" "Detected in some" 4 "Other brain neurons: 11.6;Retinal bipolar cells: 6.4" "Cell type enhanced" "Detected in many" "deep-layer corticothalamic and 6b: 7.7;deep-layer near-projecting: 15.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Plasma cells, Minor Salivary Gland - Plasma cells" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 13.5" HPA016719 Uncertain NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 109: Neurons - Neuronal signaling" 2 "HPA016719: " MC5R ENSG00000176136 "Melanocortin 5 receptor" P33032 18 13824149-13827323 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 2.5;lymphoid tissue: 1.0" "Group enriched" "Detected in some" 4 "Early spermatids: 7.0;Esophageal apical cells: 2.4;Late spermatids: 9.0;Medullary thymic epithelial cells: 4.8" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Adipocytes (Visceral), Skin - Sebaceous gland cells" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA042365, HPA058088" Approved Supported "Plasma membrane" NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" "Plasma membrane" "HPA042365: , HPA058088: " "unprognostic (6.07e-2)" MCAM "CD146, HEMCAM, MelCAM, METCAM, MUC18" ENSG00000076706 "Melanoma cell adhesion molecule" P43121 11 119308529-119321521 "CD markers, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "adipose tissue: 312.2;blood vessel: 1211.4" "Cell type enhanced" "Detected in many" "Adipocytes: 110.0;Breast myoepithelial cells: 86.1;Müller glia: 128.3;Pericytes: 272.2;Salivary myoepithelial cells: 82.1;Schwann cells: 79.7;Smooth muscle cells: 290.4;Vascular endothelial cells: 102.6;Vascular smooth muscle cells: 966.8" "Cell type enriched" "Detected in many" 5 "vascular associated smooth muscle cell: 849.7" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 309.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "skin cancer: 283.7" "Colon - Smooth muscle cells, Liver - Vascular endothelial cells, Pituitary gland - Endothelial cells, Prostate - Smooth muscle cells, Testis - Endothelial cells, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002147, HPA008848" Enhanced Supported "Plasma membrane" NA NA 200000000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 6: Non-specific - Immune response" "Cluster 69: Skin cancer - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 28 "Plasma membrane" "CAB002147: , HPA008848: " "unprognostic (5.46e-2)" "unprognostic (3.20e-2)" "unprognostic (3.13e-1)" "unprognostic (3.08e-3)" "unprognostic (4.26e-2)" "unprognostic (1.25e-1)" "unprognostic (1.22e-1)" "unprognostic (2.05e-1)" "unprognostic (1.52e-1)" "unprognostic (2.98e-2)" "unprognostic (1.81e-3)" "potential prognostic favorable (7.26e-4)" "unprognostic (2.45e-1)" "unprognostic (6.80e-3)" "unprognostic (9.00e-2)" "unprognostic (7.24e-2)" "potential prognostic unfavorable (4.77e-5)" "unprognostic (3.52e-1)" "unprognostic (1.91e-2)" "unprognostic (2.55e-1)" "unprognostic (1.74e-1)" "unprognostic (1.73e-1)" "unprognostic (2.66e-1)" "unprognostic (2.70e-2)" "unprognostic (1.95e-2)" "unprognostic (1.78e-2)" "unprognostic (3.32e-2)" "unprognostic (1.07e-2)" "unprognostic (1.06e-1)" "unprognostic (1.47e-1)" "unprognostic (1.11e-1)" MCAT "fabD, FASN2C, MCT, MCT1, MT, NET62" ENSG00000100294 "Malonyl-CoA-acyl carrier protein transacylase" Q8IVS2 22 43132209-43143398 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal efferent duct ciliated cells: 55.0;Fallopian tube ciliated cells: 66.4;Oocytes: 50.7;Respiratory ciliated cells: 53.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003122, HPA035471" Approved Supported Mitochondria NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 70: Non-specific - Protein processing" "Cluster 23: Choroid plexus - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 107: Ciliated cells - Cilia assembly & function" 44 Mitochondria "HPA003122: , HPA035471: " "unprognostic (2.34e-1)" "unprognostic (1.96e-1)" "unprognostic (1.19e-1)" "unprognostic (4.32e-2)" "unprognostic (7.02e-2)" "unprognostic (1.36e-1)" "unprognostic (1.10e-1)" "unprognostic (2.33e-1)" "unprognostic (4.94e-2)" "unprognostic (2.49e-1)" "potential prognostic favorable (5.93e-4)" "unprognostic (6.04e-3)" "unprognostic (8.19e-3)" "unprognostic (2.30e-3)" "unprognostic (1.30e-2)" "unprognostic (9.91e-3)" "unprognostic (8.29e-2)" "unprognostic (3.55e-1)" "unprognostic (1.41e-3)" "unprognostic (2.69e-1)" "unprognostic (3.13e-1)" "unprognostic (1.08e-1)" "unprognostic (1.57e-1)" "unprognostic (1.26e-1)" "unprognostic (2.90e-2)" "unprognostic (7.61e-3)" "unprognostic (7.68e-2)" "unprognostic (1.06e-2)" "unprognostic (2.04e-2)" "unprognostic (2.20e-2)" "unprognostic (7.27e-2)" MCC ENSG00000171444 "MCC regulator of WNT signaling pathway" P23508 5 113022106-113488823 "Predicted intracellular proteins" "Wnt signaling pathway" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 54.7" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 513.8;Bergmann glia: 896.4;Lacrimal acinar cells: 762.7;Respiratory basal cells: 423.0;Retinal bipolar cells: 710.2;Salivary basal cells: 463.7" "Cell type enhanced" "Detected in all" "Bergmann glia: 974.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 2.7" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Sarcoma: 43.9" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037390, HPA037391" Approved Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 94 Nucleoplasm Cytosol "HPA037390: , HPA037391: " "unprognostic (5.75e-2)" "unprognostic (5.76e-2)" "unprognostic (8.45e-2)" "unprognostic (9.89e-2)" "unprognostic (1.62e-1)" "unprognostic (3.09e-2)" "unprognostic (5.44e-2)" "potential prognostic unfavorable (1.48e-4)" "unprognostic (9.72e-2)" "unprognostic (1.02e-1)" "validated prognostic favorable (1.02e-5)" "validated prognostic favorable (7.37e-4)" "unprognostic (2.22e-1)" "unprognostic (7.71e-2)" "unprognostic (1.10e-2)" "unprognostic (1.42e-1)" "unprognostic (8.78e-2)" "unprognostic (9.12e-2)" "unprognostic (2.68e-1)" "unprognostic (2.67e-2)" "unprognostic (2.48e-2)" "unprognostic (1.36e-1)" "unprognostic (4.59e-2)" "unprognostic (1.09e-1)" "unprognostic (1.50e-1)" "unprognostic (2.10e-2)" "unprognostic (5.64e-2)" "unprognostic (2.50e-3)" "unprognostic (2.41e-1)" "unprognostic (1.95e-2)" "unprognostic (2.29e-1)" MCCC1 "MCCA, MCCCalpha" ENSG00000078070 "Methylcrotonyl-CoA carboxylase subunit 1" Q96RQ3 3 183015218-183116075 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Ligase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 251.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008310, HPA071630" Approved Enhanced Mitochondria NA NA 7700 "Cluster 29: Non-specific - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 31: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 81: Alveolar cells - Lung function" 34 Mitochondria "HPA008310: , HPA071630: " "unprognostic (2.71e-2)" "unprognostic (1.81e-2)" "unprognostic (3.37e-1)" "unprognostic (1.41e-1)" "unprognostic (3.18e-3)" "unprognostic (5.16e-2)" "unprognostic (1.67e-2)" "unprognostic (1.10e-2)" "unprognostic (2.76e-1)" "unprognostic (2.60e-2)" "potential prognostic favorable (8.81e-9)" "unprognostic (1.64e-3)" "unprognostic (7.06e-2)" "unprognostic (3.81e-1)" "unprognostic (1.37e-1)" "unprognostic (6.02e-2)" "unprognostic (9.88e-2)" "unprognostic (1.82e-2)" "unprognostic (4.02e-3)" "unprognostic (1.30e-1)" "unprognostic (1.61e-2)" "unprognostic (1.15e-1)" "unprognostic (1.55e-1)" "unprognostic (7.30e-2)" "unprognostic (5.03e-2)" "unprognostic (2.08e-1)" "unprognostic (2.93e-2)" "unprognostic (2.14e-1)" "unprognostic (1.35e-1)" "unprognostic (4.64e-2)" "unprognostic (4.37e-1)" MCCC2 "MCCB, MCCCbeta" ENSG00000131844 "Methylcrotonyl-CoA carboxylase subunit 2" Q9HCC0 5 71579531-71658706 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Ligase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 109.5" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 184.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Prostate - Prostate glandular cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038300, HPA038301, HPA061546" Enhanced Enhanced Mitochondria NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 60: Prostate cancer - Unknown function" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 14 Mitochondria "HPA038300: , HPA038301: , HPA061546: " "unprognostic (6.22e-2)" "unprognostic (1.04e-1)" "unprognostic (2.39e-1)" "unprognostic (5.48e-2)" "unprognostic (3.24e-2)" "unprognostic (4.61e-3)" "unprognostic (4.34e-2)" "unprognostic (1.08e-2)" "unprognostic (1.19e-1)" "potential prognostic unfavorable (3.31e-4)" "potential prognostic favorable (2.19e-7)" "unprognostic (5.56e-2)" "unprognostic (4.34e-3)" "unprognostic (2.40e-3)" "unprognostic (2.31e-2)" "unprognostic (2.39e-3)" "unprognostic (3.14e-1)" "unprognostic (3.51e-1)" "unprognostic (1.43e-2)" "unprognostic (8.06e-2)" "unprognostic (6.70e-2)" "unprognostic (2.54e-1)" "unprognostic (1.99e-1)" "unprognostic (2.15e-1)" "unprognostic (2.82e-2)" "unprognostic (7.71e-2)" "unprognostic (2.28e-1)" "unprognostic (6.09e-2)" "unprognostic (3.09e-1)" "unprognostic (3.28e-2)" "unprognostic (8.79e-2)" MCCD1 ENSG00000204511 "Mitochondrial coiled-coil domain 1" P59942 6 31528962-31530232 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 93 "kidney: 120.2" "Cell type enhanced" "Detected in single" "Renal collecting duct intercalated cells: 1.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Kidney Chromophobe (TCGA): 6.7;Kidney Renal Papillary Cell Carcinoma (TCGA): 1.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells" "Not detected" "Not detected" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 21 "unprognostic (2.14e-2)" "unprognostic (6.50e-1)" "unprognostic (2.70e-1)" "unprognostic (1.69e-1)" MCEE "GLOD2, MCE, MMCE" ENSG00000124370 "Methylmalonyl-CoA epimerase" Q96PE7 2 71109684-71130239 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 181.2;Myonuclei: 164.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035196 Approved Nucleoli No No 15000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 76: Non-specific - Metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 63: Non-specific - Protein processing" "Cluster 55: Myocytes - Oxidative muscle function" 6 Nucleoli "HPA035196: " "unprognostic (4.36e-2)" "unprognostic (1.20e-3)" "unprognostic (6.46e-2)" "unprognostic (1.78e-1)" "unprognostic (4.95e-2)" "unprognostic (4.13e-2)" "unprognostic (2.97e-1)" "unprognostic (1.10e-1)" "unprognostic (6.55e-3)" "unprognostic (6.28e-3)" "potential prognostic favorable (2.07e-5)" "unprognostic (2.00e-2)" "unprognostic (2.23e-2)" "potential prognostic favorable (2.50e-5)" "unprognostic (4.33e-2)" "unprognostic (3.76e-1)" "unprognostic (4.63e-2)" "unprognostic (2.16e-2)" "unprognostic (3.48e-1)" "unprognostic (1.24e-1)" "unprognostic (6.75e-2)" "unprognostic (7.17e-3)" "unprognostic (9.95e-2)" "unprognostic (2.63e-1)" "unprognostic (2.00e-1)" "unprognostic (2.46e-2)" "unprognostic (7.54e-2)" "unprognostic (2.81e-1)" "unprognostic (9.81e-2)" "unprognostic (1.61e-1)" "unprognostic (1.17e-1)" MCEMP1 "C19orf59, MGC132456" ENSG00000183019 "Mast cell expressed membrane protein 1" Q8IX19 19 7677088-7679829 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "bone marrow: 77.3;lung: 82.9;lymphoid tissue: 49.5" "Cell type enriched" "Detected in some" 4 "Neutrophils: 82.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 10.2" "Group enriched" "Detected in some" 5 "cerebral cortex: 6.2;pons: 2.8;thalamus: 2.9" "Group enriched" "Detected in many" 5 "classical monocyte: 124.0;neutrophil: 57.5" "Group enriched" "Detected in many" 5 "granulocytes: 57.5;monocytes: 124.0" "Cancer enriched" "Detected in some" 6 "Leukemia: 17.5" "Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Kidney - Macrophages, Liver - Neutrophils, Pituitary gland - Neutrophils, Prostate - Macrophages, Skeletal muscle - Neutrophils, Spleen - Neutrophils_2, Stomach - Neutrophils, Thyroid gland - Neutrophils" "Region enhanced" "Detected in single" "cerebellum: 1.3" "Not detected" "Not detected" HPA014731 Enhanced Supported "Plasma membrane" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 9 "Plasma membrane" "HPA014731: " "unprognostic (2.73e-1)" "unprognostic (2.53e-1)" "potential prognostic unfavorable (5.33e-4)" "unprognostic (4.41e-3)" "unprognostic (1.27e-1)" "potential prognostic unfavorable (2.08e-5)" "unprognostic (3.08e-2)" "unprognostic (1.76e-2)" "unprognostic (2.22e-2)" "unprognostic (8.57e-3)" "unprognostic (1.12e-1)" "unprognostic (2.05e-3)" "unprognostic (1.63e-2)" MCF2 "ARHGEF21, DBL" ENSG00000101977 "MCF.2 cell line derived transforming sequence" P10911 X 139581770-139708216 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 22.6;brain: 11.6;seminal vesicle: 14.3;testis: 14.0" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 139.3;Brain inhibitory neurons: 42.4;Cone photoreceptor cells: 111.8;Gonadotrophs: 64.1;Retinal ganglion cells: 42.5;Sertoli cells: 378.7" "Cell type enhanced" "Detected in many" "thalamic excitatory: 131.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adrenal gland - Adrenal cortex cells, Skin - Sebaceous gland cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010423 Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 7: Liver cancer - Metabolism" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 6 "Plasma membrane, Cytosol" Nucleoplasm "CAB010423: " "potential prognostic favorable (1.68e-4)" MCF2L "ARHGEF14, DBS, KIAA0362, OST" ENSG00000126217 "MCF.2 cell line derived transforming sequence like" O15068 13 112894378-113099742 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 158.2" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 222.9;Cone photoreceptor cells: 498.9;Gonadotrophs: 250.7;Lactotrophs: 253.6;Microglia: 376.6;Proximal tubule cells: 382.7;Somatotrophs: 278.2;Thyrotrophs: 204.6" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 449.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 35.9" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 37: Neurons - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 3 "unprognostic (4.46e-3)" "unprognostic (2.96e-1)" "unprognostic (2.57e-1)" "unprognostic (3.22e-1)" "unprognostic (1.88e-1)" "unprognostic (2.24e-1)" "unprognostic (1.31e-1)" "unprognostic (4.75e-2)" "unprognostic (3.07e-2)" "unprognostic (1.54e-1)" "validated prognostic favorable (7.47e-10)" "validated prognostic favorable (8.68e-5)" "potential prognostic favorable (9.71e-5)" "unprognostic (1.78e-1)" "unprognostic (6.19e-3)" "unprognostic (7.23e-2)" "unprognostic (1.16e-1)" "unprognostic (3.06e-2)" "unprognostic (2.17e-2)" "unprognostic (1.87e-1)" "unprognostic (3.03e-1)" "potential prognostic favorable (3.56e-4)" "unprognostic (1.94e-1)" "unprognostic (1.29e-1)" "unprognostic (5.93e-2)" "unprognostic (4.00e-2)" "unprognostic (2.88e-2)" "unprognostic (3.72e-2)" "unprognostic (1.47e-1)" "unprognostic (8.52e-2)" "unprognostic (1.86e-1)" MCF2L2 "ARHGEF22, KIAA0861" ENSG00000053524 "MCF.2 cell line derived transforming sequence-like 2" Q86YR7 3 183178041-183428778 "Disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Diabetes mellitus" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 32.6;retina: 26.3" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 977.1;Cone photoreceptor cells: 1045.4;Enterocytes: 567.0;Esophageal apical cells: 732.1;Esophageal suprabasal cells: 449.0;Retinal bipolar cells: 581.0;Rod photoreceptor cells: 732.9" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 4.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "T-reg: 1.4" "Lineage enriched" "Detected in single" 14 "T-cells: 1.4" "Low cancer specificity" "Detected in some" "Colon - Enteric glia cells, Pancreas - Beta cells, Prostate - Fibroblasts, Spleen - Endothelial cells, Testis - Late spermatids, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "HPA038946, HPA038947, HPA061485" Uncertain Approved "Centriolar satellite,Cytosol" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "Centriolar satellite, Cytosol" "HPA038946: , HPA038947: , HPA061485: " "unprognostic (2.03e-1)" "unprognostic (4.98e-2)" "potential prognostic favorable (1.92e-5)" "unprognostic (2.67e-1)" "unprognostic (2.24e-1)" "unprognostic (1.97e-1)" "unprognostic (6.55e-3)" "unprognostic (2.11e-1)" "unprognostic (1.36e-1)" "unprognostic (6.24e-2)" MCFD2 "F5F8D, LMAN1IP, SDNSF" ENSG00000180398 "Multiple coagulation factor deficiency 2, ER cargo receptor complex subunit" Q8NI22 2 46901870-46941855 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "ER-Golgi transport, Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 279.7;Müller glia: 289.3;Salivary acinar cells: 353.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022410, HPA034593" Supported "Intracellular and membrane" Transport NA NA 530000 "Cluster 41: Basophils - Unknown function" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 1: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 23 "CAB022410: , HPA034593: " "unprognostic (2.94e-2)" "unprognostic (1.81e-2)" "unprognostic (2.93e-1)" "unprognostic (3.56e-3)" "unprognostic (1.92e-1)" "unprognostic (9.31e-3)" "unprognostic (1.20e-1)" "unprognostic (8.86e-3)" "unprognostic (5.09e-2)" "unprognostic (1.53e-3)" "potential prognostic favorable (6.19e-5)" "unprognostic (1.08e-2)" "unprognostic (5.74e-3)" "unprognostic (2.81e-2)" "potential prognostic unfavorable (5.28e-4)" "unprognostic (2.02e-1)" "unprognostic (1.50e-2)" "unprognostic (1.16e-1)" "unprognostic (3.31e-1)" "unprognostic (1.02e-1)" "unprognostic (5.95e-2)" "unprognostic (5.21e-3)" "potential prognostic unfavorable (1.48e-4)" "unprognostic (1.37e-1)" "unprognostic (1.58e-1)" "unprognostic (3.48e-1)" "unprognostic (1.96e-2)" "unprognostic (2.26e-3)" "unprognostic (2.92e-1)" "unprognostic (2.63e-2)" "unprognostic (2.16e-1)" MCHR1 "GPR24, MCH1R, SLC1" ENSG00000128285 "Melanin concentrating hormone receptor 1" Q99705 22 40679273-40682812 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.3;endometrium 1: 5.5;ovary: 9.9" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 2.2;Brain inhibitory neurons: 2.8;Decidual stromal cells: 1.9;Gonadotrophs: 3.0;Melanocytes: 6.2;Other brain neurons: 4.4;Ovarian stromal cells: 6.7;Pancreatic islet cells: 8.0;Retinal amacrine cells: 1.4" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in some" 7 "Glioblastoma Multiforme (TCGA): 6.8;Kidney Renal Clear Cell Carcinoma (TCGA): 5.9;Liver Hepatocellular Carcinoma (TCGA): 1.7;Skin Cutaneous Melanoma (TCGA): 4.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Rhabdoid: 27.6" "Adrenal gland - Adrenal medulla cells, Pituitary gland - Corticotropes" "Low region specificity" "Detected in many" "Region enhanced" "Detected in all" "basal ganglia: 33.3" NA NA "Cluster 65: Brain - Transcription" "Cluster 53: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 94: Gonadal somatic cells - Mixed function" "unprognostic (2.21e-2)" "unprognostic (8.21e-3)" "unprognostic (6.94e-2)" "unprognostic (2.49e-2)" "unprognostic (3.93e-2)" "unprognostic (4.15e-3)" "unprognostic (1.61e-1)" "unprognostic (8.06e-2)" MCHR2 "GPR145, MCH2, MCH2R, SLT" ENSG00000152034 "Melanin concentrating hormone receptor 2" Q969V1 6 99918519-99994247 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 18 "brain: 5.1;testis: 1.4" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 19.7;Brain inhibitory neurons: 7.9;Late primary spermatocytes: 3.4;Late spermatids: 4.4;Medullary thymic epithelial cells: 2.4;Retinal amacrine cells: 6.2;Retinal pigment epithelial cells: 4.3" "Cell type enhanced" "Detected in many" "deep-layer intratelencephalic: 69.1;upper-layer intratelencephalic: 116.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in many" HPA030115 Supported "Nucleoplasm,Vesicles,Plasma membrane,Primary cilium tip,Basal body" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 35: Neurons - Synaptic function & neurogenesis" "Plasma membrane" "Nucleoplasm, Vesicles, Primary cilium tip, Basal body" "HPA030115: " MCIDAS "IDAS, MCI, MCIN" ENSG00000234602 "Multiciliate differentiation and DNA synthesis associated cell cycle protein" D6RGH6 5 55219564-55227315 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cilium biogenesis/degradation, Transcription, Transcription regulation" Activator "Ciliopathy, Disease variant, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "parathyroid gland: 2.6;stomach 1: 1.1" "Cell type enriched" "Detected in some" 7 "Respiratory deuterosomal cells: 57.0" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA049981, HPA058073" Uncertain Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 69: Parathyroid gland - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 3 "Nuclear bodies" Nucleoplasm "HPA049981: , HPA058073: " "unprognostic (1.35e-1)" "unprognostic (1.90e-3)" "unprognostic (2.26e-1)" "unprognostic (6.51e-2)" "unprognostic (4.06e-2)" "unprognostic (6.61e-2)" "unprognostic (6.31e-2)" MCL1 "BCL2L3, Mcl-1" ENSG00000143384 "MCL1 apoptosis regulator, BCL2 family member" Q07820 1 150560895-150579738 "Cancer-related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Differentiation" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 646.6" "Cell type enhanced" "Detected in many" "monocytes: 1779.3;Neutrophils: 5897.5" "Cell type enhanced" "Detected in all" "endothelial cell: 125.3;leukocyte: 128.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 106.6" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002781, HPA008455, HPA031125, CAB068195" Enhanced Enhanced Mitochondria Yes No "Cluster 21: Neutrophils - Unknown function" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 44: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 63 Mitochondria "CAB002781: , CAB068195: , HPA008455: , HPA031125: " "unprognostic (2.71e-2)" "unprognostic (3.47e-1)" "unprognostic (6.85e-3)" "unprognostic (5.89e-3)" "unprognostic (4.59e-2)" "unprognostic (2.80e-2)" "unprognostic (2.62e-1)" "unprognostic (2.40e-1)" "unprognostic (2.79e-2)" "unprognostic (4.12e-1)" "potential prognostic favorable (6.96e-4)" "unprognostic (1.74e-2)" "unprognostic (2.68e-2)" "unprognostic (1.31e-2)" "unprognostic (2.81e-2)" "unprognostic (1.75e-2)" "unprognostic (4.14e-2)" "unprognostic (2.37e-2)" "unprognostic (2.09e-1)" "unprognostic (2.87e-3)" "unprognostic (7.62e-2)" "unprognostic (1.06e-2)" "unprognostic (1.16e-2)" "unprognostic (8.05e-2)" "unprognostic (3.92e-1)" "unprognostic (2.35e-2)" "unprognostic (1.05e-1)" "unprognostic (5.04e-2)" "unprognostic (2.89e-1)" "unprognostic (7.09e-2)" "unprognostic (1.26e-1)" MCM10 "CNA43, DNA43, PRO2249" ENSG00000065328 "Minichromosome maintenance 10 replication initiation factor" Q7L590 10 13161558-13211110 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA replication" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 8.7;lymphoid tissue: 7.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 17.2;Differentiating spermatogonia: 16.4;Early primary spermatocytes: 32.1;Erythrocyte progenitors: 96.8;Extravillous trophoblasts: 28.4;Megakaryocyte progenitors: 62.8;Megakaryocytes: 18.5;Migrating cytotrophoblasts: 27.3;Monocyte progenitors: 47.7;Neutrophil progenitors: 22.1" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Pituitary gland - Thyrotropes, Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA045899, HPA071952" Approved Supported Nucleoplasm,Nucleoli Yes Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 48: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 31 "Nucleoplasm, Nucleoli" "HPA045899: , HPA071952: " "unprognostic (2.08e-3)" "unprognostic (2.73e-2)" "unprognostic (2.08e-1)" "unprognostic (5.97e-2)" "unprognostic (1.70e-1)" "unprognostic (1.11e-1)" "unprognostic (1.66e-1)" "potential prognostic favorable (3.76e-4)" "unprognostic (1.56e-2)" "unprognostic (1.88e-3)" "validated prognostic unfavorable (8.32e-9)" "validated prognostic unfavorable (4.21e-8)" "validated prognostic unfavorable (3.72e-5)" "validated prognostic unfavorable (3.15e-4)" "unprognostic (1.68e-1)" "unprognostic (1.52e-2)" "unprognostic (4.38e-2)" "unprognostic (1.94e-1)" "validated prognostic unfavorable (5.15e-4)" "validated prognostic unfavorable (1.11e-4)" "unprognostic (1.05e-2)" "unprognostic (2.06e-2)" "unprognostic (1.45e-2)" "unprognostic (6.80e-2)" "unprognostic (1.61e-1)" "unprognostic (2.17e-1)" MCM2 "BM28, CCNL1, cdc19, CDCL1, D3S3194, DFNA70, KIAA0030" ENSG00000073111 "Minichromosome maintenance complex component 2" P49736 3 127598410-127622436 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 63.9;lymphoid tissue: 35.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 77.1;Differentiating spermatogonia: 37.8;Erythrocyte progenitors: 121.7;Extravillous trophoblasts: 28.4;Megakaryocyte progenitors: 62.7;Megakaryocyte-Erythroid progenitors: 38.4;Migrating cytotrophoblasts: 58.6;Monocyte progenitors: 44.2;Neutrophil progenitors: 30.1;Platelets: 28.2;Syncytiotrophoblasts: 30.4" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB000303, HPA031450, HPA031495, HPA031496" Enhanced Supported "Nucleoplasm,Vesicles,Primary cilium,Cytosol" Yes Yes 160000 "Cluster 16: Non-specific - Cell proliferation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 227 Nucleoplasm "Vesicles, Primary cilium, Cytosol" "CAB000303: , HPA031450: , HPA031495: , HPA031496: " "unprognostic (1.64e-1)" "unprognostic (1.37e-1)" "unprognostic (1.18e-1)" "unprognostic (5.08e-2)" "unprognostic (4.13e-1)" "unprognostic (1.88e-1)" "unprognostic (2.18e-1)" "unprognostic (3.68e-1)" "unprognostic (5.12e-2)" "unprognostic (8.23e-3)" "unprognostic (5.57e-2)" "unprognostic (6.29e-3)" "unprognostic (5.65e-3)" "validated prognostic unfavorable (1.10e-6)" "validated prognostic unfavorable (8.17e-8)" "unprognostic (1.54e-3)" "unprognostic (2.22e-3)" "unprognostic (3.03e-2)" "unprognostic (1.68e-1)" "unprognostic (1.84e-1)" "unprognostic (1.84e-1)" "potential prognostic unfavorable (3.55e-4)" "unprognostic (4.09e-2)" "unprognostic (5.96e-3)" "unprognostic (2.65e-2)" "unprognostic (2.34e-2)" "unprognostic (1.64e-2)" "unprognostic (3.06e-2)" "unprognostic (8.52e-2)" "unprognostic (7.68e-2)" "unprognostic (4.10e-1)" MCM3 ENSG00000112118 "Minichromosome maintenance complex component 3" P25205 6 52264014-52284881 "Cancer-related genes, Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 155.9;Erythrocyte progenitors: 221.2;Megakaryocyte progenitors: 175.8;Megakaryocyte-Erythroid progenitors: 105.9;Migrating cytotrophoblasts: 124.1;Monocyte progenitors: 99.9;Oocytes: 105.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002162, HPA004789, HPA004790" Supported Approved Nucleoplasm NA Yes 52000 "Cluster 16: Non-specific - Cell proliferation" "Cluster 80: Thymus - Adaptive immune response" "Cluster 25: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 76 Nucleoplasm "CAB002162: , HPA004789: , HPA004790: " "unprognostic (4.63e-1)" "unprognostic (4.31e-2)" "unprognostic (8.05e-2)" "unprognostic (1.89e-1)" "unprognostic (2.07e-1)" "unprognostic (2.01e-1)" "unprognostic (2.88e-1)" "unprognostic (5.15e-2)" "unprognostic (4.11e-2)" "unprognostic (1.20e-3)" "unprognostic (2.57e-3)" "unprognostic (9.29e-2)" "unprognostic (1.19e-1)" "validated prognostic unfavorable (4.66e-5)" "validated prognostic unfavorable (8.22e-6)" "unprognostic (8.17e-3)" "unprognostic (2.11e-3)" "unprognostic (6.00e-2)" "unprognostic (2.34e-2)" "unprognostic (1.88e-3)" "unprognostic (1.04e-2)" "unprognostic (3.37e-2)" "unprognostic (2.05e-2)" "unprognostic (1.93e-1)" "unprognostic (1.10e-1)" "unprognostic (3.58e-2)" "potential prognostic unfavorable (9.02e-4)" "unprognostic (2.25e-2)" "unprognostic (2.40e-1)" "unprognostic (1.57e-2)" "unprognostic (1.67e-1)" MCM3AP "GANP, KIAA0572, Map80, SAC3" ENSG00000160294 "Minichromosome maintenance complex component 3 associated protein" O60318 21 46235133-46286297 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Immunity, mRNA transport, Protein transport, Translocation, Transport" "Acyltransferase, Transferase" "Intellectual disability, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021527, HPA032103" Approved Supported "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 47: Leukemia - Hemostasis" "Cluster 7: Non-specific - Transcription" 25 "Nuclear membrane, Cytosol" Nucleoplasm "HPA021527: , HPA032103: " "unprognostic (2.00e-1)" "unprognostic (8.76e-2)" "unprognostic (2.93e-2)" "unprognostic (2.17e-2)" "unprognostic (2.84e-1)" "unprognostic (6.85e-2)" "unprognostic (1.12e-1)" "unprognostic (1.83e-1)" "unprognostic (3.01e-2)" "unprognostic (1.11e-1)" "potential prognostic favorable (5.10e-6)" "unprognostic (1.34e-2)" "unprognostic (1.59e-1)" "unprognostic (1.41e-1)" "unprognostic (8.22e-2)" "unprognostic (1.07e-1)" "unprognostic (3.52e-2)" "unprognostic (1.51e-2)" "unprognostic (1.79e-1)" "unprognostic (5.47e-3)" "unprognostic (4.28e-1)" "unprognostic (2.41e-1)" "unprognostic (1.47e-1)" "unprognostic (3.56e-1)" "unprognostic (4.91e-2)" "unprognostic (2.47e-2)" "unprognostic (5.61e-2)" "unprognostic (2.95e-1)" "unprognostic (3.94e-2)" "unprognostic (4.63e-3)" "unprognostic (1.73e-1)" MCM4 "CDC21, CDC54, hCdc21, MGC33310, P1-Cdc21" ENSG00000104738 "Minichromosome maintenance complex component 4" P33991 8 47960185-47978160 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 52.0" "Cell type enhanced" "Detected in many" "Early spermatids: 160.3;Erythrocyte progenitors: 288.2;Late primary spermatocytes: 147.1;Late spermatids: 110.6;Megakaryocyte progenitors: 134.0;Monocyte progenitors: 123.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Mitotic cells (Lung), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004497, HPA004873, HPA031052" Enhanced Enhanced Nucleoplasm NA Yes 85000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 31: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 90 Nucleoplasm "CAB004497: , HPA004873: , HPA031052: " "unprognostic (7.68e-2)" "unprognostic (4.25e-2)" "unprognostic (1.52e-1)" "unprognostic (7.09e-2)" "unprognostic (4.67e-2)" "unprognostic (3.64e-1)" "unprognostic (7.39e-2)" "unprognostic (1.59e-1)" "unprognostic (1.71e-1)" "potential prognostic unfavorable (9.02e-5)" "unprognostic (3.65e-3)" "unprognostic (1.29e-3)" "unprognostic (4.88e-3)" "validated prognostic unfavorable (2.36e-5)" "validated prognostic unfavorable (5.39e-5)" "validated prognostic unfavorable (1.65e-4)" "validated prognostic unfavorable (6.35e-5)" "unprognostic (1.58e-2)" "unprognostic (1.55e-1)" "unprognostic (2.35e-1)" "unprognostic (2.01e-1)" "potential prognostic unfavorable (4.49e-4)" "unprognostic (5.63e-2)" "unprognostic (1.68e-2)" "unprognostic (4.44e-2)" "unprognostic (1.72e-2)" "unprognostic (1.65e-2)" "unprognostic (1.04e-1)" "unprognostic (1.73e-1)" "unprognostic (4.27e-2)" "unprognostic (2.26e-1)" MCM5 CDC46 ENSG00000100297 "Minichromosome maintenance complex component 5" P33992 22 35400134-35425431 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 130.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 178.9;Differentiating spermatogonia: 91.9;Erythrocyte progenitors: 183.2;Extravillous trophoblasts: 81.7;Megakaryocyte progenitors: 89.9;Migrating cytotrophoblasts: 147.3;Monocyte progenitors: 89.8;Oocytes: 133.5;Syncytiotrophoblasts: 79.5" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 22.8;leukocyte: 13.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000101, HPA000845, HPA052880" Enhanced Enhanced Nucleoplasm Yes Yes 68000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 30: White matter - Myelination" "Cluster 66: Non-specific - Mitochondria" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 76 Nucleoplasm "CAB000101: , HPA000845: , HPA052880: " "unprognostic (1.43e-1)" "unprognostic (4.79e-2)" "unprognostic (4.29e-2)" "unprognostic (4.26e-2)" "unprognostic (8.39e-2)" "unprognostic (3.11e-1)" "unprognostic (3.70e-1)" "unprognostic (3.15e-3)" "unprognostic (1.21e-2)" "unprognostic (5.79e-3)" "unprognostic (3.97e-3)" "unprognostic (1.82e-1)" "unprognostic (4.30e-2)" "validated prognostic unfavorable (4.86e-5)" "validated prognostic unfavorable (4.47e-7)" "potential prognostic unfavorable (4.15e-7)" "unprognostic (5.09e-2)" "unprognostic (1.63e-2)" "unprognostic (1.07e-2)" "unprognostic (1.20e-1)" "unprognostic (2.88e-2)" "unprognostic (9.34e-3)" "unprognostic (3.96e-2)" "unprognostic (3.91e-2)" "unprognostic (1.21e-2)" "unprognostic (5.05e-2)" "unprognostic (1.54e-1)" "unprognostic (1.23e-2)" "unprognostic (3.10e-1)" "unprognostic (2.56e-2)" "unprognostic (1.91e-1)" MCM6 Mis5 ENSG00000076003 "Minichromosome maintenance complex component 6" Q14566 2 135839626-135876443 "Enzymes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 45.2" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 171.2;Megakaryocyte progenitors: 112.6;Megakaryocyte-Erythroid progenitors: 62.8;Monocyte progenitors: 94.8;Neutrophil progenitors: 58.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004818, CAB009577" Enhanced Supported Nucleoplasm NA Yes 180000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 35: Non-specific - DNA binding" "Cluster 58: Non-specific - Nuclear processes" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 101 Nucleoplasm "CAB009577: , HPA004818: " "unprognostic (2.07e-1)" "unprognostic (1.26e-1)" "unprognostic (1.81e-1)" "unprognostic (2.73e-2)" "unprognostic (8.32e-2)" "unprognostic (1.75e-1)" "unprognostic (1.24e-1)" "unprognostic (2.08e-1)" "unprognostic (5.45e-2)" "potential prognostic unfavorable (4.56e-4)" "unprognostic (3.61e-3)" "unprognostic (1.85e-1)" "potential prognostic unfavorable (1.30e-7)" "validated prognostic unfavorable (1.03e-6)" "validated prognostic unfavorable (6.26e-8)" "unprognostic (1.21e-3)" "potential prognostic unfavorable (7.11e-4)" "unprognostic (2.54e-2)" "unprognostic (6.26e-2)" "unprognostic (5.69e-2)" "unprognostic (2.24e-1)" "unprognostic (2.10e-2)" "unprognostic (3.24e-2)" "unprognostic (6.46e-2)" "unprognostic (1.74e-3)" "unprognostic (9.69e-2)" "unprognostic (1.40e-3)" "unprognostic (8.94e-2)" "unprognostic (7.37e-2)" "unprognostic (4.99e-2)" "unprognostic (1.86e-1)" MCM7 "CDC47, MCM2, PPP1R104" ENSG00000166508 "Minichromosome maintenance complex component 7" P33993 7 100092728-100101940 "Cancer-related genes, Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 170.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 156.6;Erythrocyte progenitors: 238.4;Esophageal basal cells: 117.5;Megakaryocyte progenitors: 127.5;Migrating cytotrophoblasts: 140.5;Monocyte progenitors: 114.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002163, HPA003898, CAB016312" Enhanced Approved "Nucleoplasm,Basal body,Cytosol" NA Yes 62000 "Cluster 14: Non-specific - Unknown function" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 6: Non-specific - Immune response" "Cluster 39: Non-specific - Transcription" "Cluster 27: Non-specific - Cell proliferation" 148 Nucleoplasm "Basal body, Cytosol" "CAB002163: , CAB016312: , HPA003898: " "unprognostic (1.03e-1)" "unprognostic (1.97e-1)" "unprognostic (4.53e-2)" "unprognostic (3.34e-2)" "unprognostic (2.65e-1)" "unprognostic (1.48e-1)" "unprognostic (1.23e-1)" "unprognostic (1.85e-2)" "unprognostic (1.23e-1)" "potential prognostic unfavorable (4.00e-5)" "potential prognostic favorable (3.26e-5)" "unprognostic (2.10e-1)" "unprognostic (2.73e-1)" "validated prognostic unfavorable (8.66e-5)" "validated prognostic unfavorable (1.47e-6)" "potential prognostic unfavorable (5.19e-4)" "unprognostic (1.08e-2)" "unprognostic (1.23e-2)" "unprognostic (2.71e-2)" "unprognostic (1.08e-1)" "unprognostic (1.36e-3)" "unprognostic (8.44e-3)" "unprognostic (3.09e-3)" "unprognostic (1.34e-2)" "unprognostic (2.93e-2)" "unprognostic (1.71e-2)" "unprognostic (7.29e-3)" "unprognostic (5.66e-2)" "unprognostic (1.04e-1)" "unprognostic (2.59e-2)" "unprognostic (1.06e-1)" MCM8 "C20orf154, dJ967N21.5, MGC119522, MGC119523, MGC12866, MGC4816, REC" ENSG00000125885 "Minichromosome maintenance 8 homologous recombination repair factor" Q9UJA3 20 5950652-5998977 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair, DNA replication" "DNA-binding, Helicase, Hydrolase" "Disease variant, Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 12.6;Distal convoluted tubule cells: 13.0;Early primary spermatocytes: 8.9;Ependymal cells: 8.2;Erythrocyte progenitors: 8.5;Loop of henle epithelial cells: 19.1;Microglia: 7.7;Oligodendrocytes: 9.9;Papillary tip epithelial cells: 8.8;Podocytes: 7.5;Proximal tubule cells: 14.5;Renal collecting duct intercalated cells: 14.5;Renal collecting duct principal cells: 15.3;Renal connecting tubule cells: 12.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045141, HPA066433" Supported Nucleoplasm,Cytosol NA NA "Cluster 32: Basophils - Transcription" "Cluster 39: Testis - Nuclear processes" "Cluster 25: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 102: Non-specific - Mixed function" 16 Nucleoplasm Cytosol "HPA045141: , HPA066433: " "unprognostic (1.70e-3)" "unprognostic (1.10e-1)" "unprognostic (8.67e-2)" "unprognostic (1.39e-1)" "unprognostic (1.11e-1)" "unprognostic (1.61e-1)" "unprognostic (3.27e-1)" "unprognostic (7.37e-2)" "unprognostic (1.90e-1)" "unprognostic (1.20e-2)" "unprognostic (3.09e-2)" "unprognostic (7.91e-3)" "unprognostic (1.69e-1)" "potential prognostic unfavorable (1.00e-6)" "unprognostic (1.97e-3)" "validated prognostic unfavorable (8.10e-4)" "validated prognostic unfavorable (9.62e-4)" "unprognostic (1.30e-2)" "unprognostic (5.61e-2)" "unprognostic (2.17e-1)" "unprognostic (3.53e-1)" "unprognostic (1.64e-3)" "unprognostic (8.72e-3)" "unprognostic (8.49e-2)" "unprognostic (3.89e-2)" "unprognostic (3.05e-2)" "unprognostic (2.68e-2)" "unprognostic (8.60e-2)" "unprognostic (1.52e-1)" "unprognostic (2.35e-3)" "unprognostic (3.49e-2)" MCM9 "C6orf61, dJ329L24.3, FLJ20170, MCMDC1, MGC35304" ENSG00000111877 "Minichromosome maintenance 9 homologous recombination repair factor" Q9NXL9 6 118813442-118935162 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031137 Approved Approved Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 58: Skin - Keratinization" "Cluster 11: White matter - Signal transduction" "Cluster 28: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" 32 Nucleoplasm "HPA031137: " "unprognostic (2.42e-1)" "unprognostic (1.75e-2)" "unprognostic (5.99e-2)" "unprognostic (3.80e-2)" "unprognostic (2.30e-1)" "unprognostic (6.64e-2)" "unprognostic (4.67e-2)" "unprognostic (6.44e-2)" "unprognostic (1.06e-1)" "unprognostic (4.02e-2)" "potential prognostic favorable (7.42e-4)" "unprognostic (3.81e-2)" "unprognostic (9.50e-2)" "unprognostic (7.95e-3)" "unprognostic (1.23e-1)" "unprognostic (2.66e-1)" "unprognostic (6.44e-2)" "unprognostic (2.27e-1)" "unprognostic (6.35e-2)" "unprognostic (7.76e-2)" "unprognostic (1.40e-1)" "unprognostic (2.30e-1)" "unprognostic (1.79e-1)" "unprognostic (2.69e-1)" "unprognostic (8.31e-3)" "unprognostic (1.55e-1)" "unprognostic (2.66e-2)" "unprognostic (2.51e-1)" "unprognostic (1.55e-1)" "unprognostic (2.25e-1)" "unprognostic (4.74e-2)" MCMBP "C10orf119, FLJ13081, MCM-BP" ENSG00000197771 "Minichromosome maintenance complex binding protein" Q9BTE3 10 119829404-119892556 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA replication, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 156.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013792, HPA038481" Uncertain Supported "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 38 Nucleoplasm "Cell Junctions, Cytosol" "CAB013792: , HPA038481: " "unprognostic (3.12e-1)" "unprognostic (9.03e-3)" "unprognostic (8.04e-2)" "unprognostic (2.88e-1)" "unprognostic (1.03e-1)" "unprognostic (2.64e-1)" "unprognostic (2.63e-3)" "unprognostic (2.05e-1)" "unprognostic (1.83e-2)" "potential prognostic favorable (1.29e-4)" "unprognostic (6.18e-2)" "unprognostic (1.07e-1)" "unprognostic (9.43e-3)" "unprognostic (5.93e-2)" "unprognostic (3.18e-2)" "unprognostic (3.88e-2)" "unprognostic (5.69e-2)" "unprognostic (1.79e-1)" "unprognostic (1.45e-2)" "unprognostic (1.32e-2)" "unprognostic (2.18e-2)" "unprognostic (1.24e-1)" "unprognostic (1.03e-2)" "unprognostic (6.95e-2)" "unprognostic (1.14e-2)" "unprognostic (1.86e-1)" "unprognostic (3.75e-2)" "unprognostic (4.58e-1)" "unprognostic (7.81e-2)" "unprognostic (3.21e-1)" MCMDC2 "C8orf45, FLJ25692" ENSG00000178460 "Minichromosome maintenance domain containing 2" Q4G0Z9 8 66870749-66922048 "Predicted intracellular proteins" "DNA damage, DNA repair, Meiosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 11.2" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 90.2;Early spermatids: 41.7;Late primary spermatocytes: 72.8;Myonuclei: 42.8;Retinal ganglion cells: 27.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA026522 Approved "Actin filaments" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 40: Non-specific - Mixed function" "Cluster 30: White matter - Myelination" "Cluster 25: Non-specific - Ribosome" "Cluster 3: Early primary spermatocytes - Early meiosis" 1 "Actin filaments" "HPA026522: " "unprognostic (5.29e-2)" "unprognostic (3.79e-3)" "unprognostic (1.47e-2)" "unprognostic (2.91e-2)" "unprognostic (1.58e-1)" "unprognostic (1.99e-2)" "unprognostic (3.51e-2)" "unprognostic (1.29e-1)" "potential prognostic unfavorable (1.21e-4)" "potential prognostic unfavorable (2.32e-4)" "unprognostic (2.72e-2)" "potential prognostic unfavorable (1.88e-4)" "potential prognostic unfavorable (7.97e-5)" "unprognostic (6.06e-3)" "unprognostic (1.35e-1)" "unprognostic (9.60e-2)" "unprognostic (3.73e-1)" "unprognostic (2.27e-1)" "unprognostic (2.47e-1)" "unprognostic (9.17e-2)" "unprognostic (3.58e-1)" "unprognostic (1.81e-2)" "unprognostic (3.49e-2)" "unprognostic (2.44e-1)" "unprognostic (9.75e-2)" "unprognostic (8.32e-2)" "unprognostic (2.58e-1)" "unprognostic (1.11e-2)" MCOLN1 "ML4, MLIV, MST080, MSTP080, TRPM-L1, TRPML1" ENSG00000090674 "Mucolipin TRP cation channel 1" Q9GZU1 19 7522624-7534009 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Adaptive immunity, Calcium transport, Immunity, Ion transport, Transport" "Ion channel" "Corneal dystrophy, Disease variant, Mucolipidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gonadotrophs: 84.9;Hofbauer cells: 111.6;Kupffer cells: 136.3;Macrophages: 67.5;Neutrophils: 74.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 118.2;classical monocyte: 45.3;eosinophil: 106.1;intermediate monocyte: 95.7;neutrophil: 41.4;non-classical monocyte: 105.7" "Group enriched" "Detected in all" 5 "granulocytes: 118.2;monocytes: 105.7" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adrenal gland - Adrenal cortex cells, Lung - Macrophages, Prostate - Macrophages, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031763, CAB032637" Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 5: Spleen - Immune response" "Cluster 27: Non-specific - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 7 "Plasma membrane" Cytosol "CAB032637: , HPA031763: " "unprognostic (8.33e-2)" "unprognostic (3.06e-2)" "unprognostic (1.47e-1)" "unprognostic (2.74e-3)" "unprognostic (1.18e-1)" "unprognostic (6.11e-2)" "unprognostic (1.65e-1)" "unprognostic (6.66e-2)" "unprognostic (1.17e-1)" "potential prognostic unfavorable (4.86e-4)" "potential prognostic favorable (1.04e-6)" "unprognostic (1.65e-1)" "unprognostic (6.02e-2)" "unprognostic (1.85e-2)" "unprognostic (2.23e-2)" "unprognostic (1.84e-1)" "unprognostic (8.75e-2)" "unprognostic (1.59e-1)" "unprognostic (1.46e-1)" "unprognostic (3.87e-1)" "unprognostic (1.43e-1)" "potential prognostic favorable (4.11e-4)" "unprognostic (1.02e-1)" "unprognostic (3.06e-1)" "unprognostic (2.86e-3)" "unprognostic (1.07e-2)" "unprognostic (2.77e-1)" "unprognostic (2.78e-1)" "unprognostic (2.68e-2)" "unprognostic (1.44e-1)" "unprognostic (1.24e-1)" MCOLN2 "FLJ36691, TRP-ML2, TRPML2" ENSG00000153898 "Mucolipin TRP cation channel 2" Q8IZK6 1 84925583-84997113 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Adaptive immunity, Calcium transport, Immunity, Innate immunity, Ion transport, Protein transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 8.5;intestine: 14.1;lymphoid tissue: 12.3" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 69.4;B-cells: 77.0;cDC: 246.8;Colonocytes: 45.0;Early spermatids: 51.1;Endometrial luminal cells: 65.6;Late primary spermatocytes: 52.6;Macrophages: 61.3;pDCs: 165.0;T-cells: 65.6" "Cell type enriched" "Detected in many" 15 "leukocyte: 62.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 29.6" "Group enriched" "Detected in many" 15 "B-cells: 10.3;dendritic cells: 29.6;T-cells: 8.8" "Cancer enriched" "Detected in many" 5 "lymphoma: 27.9" "Adipose subcutaneous - T-cells, Liver - T-cells, Spleen - B-cells (Spleen), Testis - Early spermatids, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA019114 Uncertain NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 6: Non-specific - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 82: Dendritic cells - Antigen presentation" 3 "HPA019114: " "unprognostic (2.90e-2)" "unprognostic (7.76e-2)" "unprognostic (3.04e-2)" "unprognostic (9.32e-2)" "unprognostic (5.25e-2)" "unprognostic (3.34e-3)" "unprognostic (4.25e-1)" "unprognostic (3.52e-2)" "unprognostic (5.56e-2)" "unprognostic (1.42e-1)" "unprognostic (6.50e-2)" "potential prognostic favorable (3.09e-5)" "potential prognostic favorable (2.47e-4)" "unprognostic (3.15e-1)" "unprognostic (2.88e-2)" "unprognostic (6.94e-2)" "unprognostic (3.41e-2)" "unprognostic (2.18e-2)" "unprognostic (3.03e-2)" "unprognostic (1.43e-3)" "unprognostic (5.14e-2)" "unprognostic (1.64e-1)" "unprognostic (1.95e-1)" "unprognostic (2.38e-1)" "unprognostic (1.89e-2)" "unprognostic (8.67e-2)" "unprognostic (4.48e-2)" MCOLN3 "FLJ11006, TRP-ML3, TRPML3" ENSG00000055732 "Mucolipin TRP cation channel 3" Q8TDD5 1 85018082-85048500 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adrenal gland: 41.3;epididymis: 13.3;parathyroid gland: 33.2" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 433.2;Corticotrophs: 96.5;Epididymal principal cells: 60.1;Gonadotrophs: 259.4;Melanocytes: 280.9;Neuroendocrine cells: 88.8;Pituitary stem cells: 102.6;Somatotrophs: 59.4" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 20.1;hippocampal dentate gyrus: 43.9" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 12.9" "Group enriched" "Detected in many" 5 "cerebral cortex: 8.3;choroid plexus: 7.4;hippocampal formation: 7.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 12.1" "Adrenal gland - Adrenal cortex cells, Lung - Fibroblasts_1, Skeletal muscle - Fibroblasts" "Not detected" "Not detected" "Region enhanced" "Detected in single" "olfactory bulb: 1.2" "HPA018106, HPA062137" Enhanced NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 29: Forebrain - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 18: Adrenal cortex cells - Steroidogensis" 2 "HPA018106: , HPA062137: " "unprognostic (2.91e-1)" "unprognostic (1.02e-1)" "unprognostic (8.03e-3)" "unprognostic (4.79e-2)" "unprognostic (5.28e-2)" "unprognostic (2.48e-3)" "unprognostic (5.26e-3)" "unprognostic (1.37e-1)" "unprognostic (4.49e-2)" "unprognostic (3.57e-2)" "unprognostic (1.58e-1)" "unprognostic (2.73e-3)" "unprognostic (3.98e-1)" "unprognostic (5.08e-2)" "unprognostic (4.01e-3)" "unprognostic (7.73e-3)" "unprognostic (2.79e-1)" "unprognostic (2.57e-1)" "unprognostic (1.95e-1)" "unprognostic (1.19e-1)" MCPH1 "BRIT1, FLJ12847" ENSG00000147316 "Microcephalin 1" Q8NEM0 8 6406592-6648508 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Intellectual disability, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008238, CAB012177" Supported NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 9: Non-specific - Receptor signaling" "Cluster 59: Leukemia - T-cell receptor" "Cluster 7: Non-specific - Transcription" 19 "CAB012177: , HPA008238: " "unprognostic (2.51e-2)" "unprognostic (1.77e-1)" "unprognostic (3.02e-1)" "unprognostic (1.02e-1)" "unprognostic (2.55e-2)" "unprognostic (4.83e-2)" "unprognostic (2.62e-1)" "unprognostic (1.26e-2)" "unprognostic (1.46e-2)" "potential prognostic unfavorable (1.10e-4)" "potential prognostic favorable (9.88e-8)" "unprognostic (1.53e-3)" "unprognostic (9.94e-2)" "unprognostic (5.84e-3)" "unprognostic (1.39e-1)" "unprognostic (6.72e-2)" "unprognostic (3.40e-1)" "unprognostic (1.14e-1)" "unprognostic (2.42e-2)" "unprognostic (4.93e-2)" "unprognostic (8.16e-3)" "unprognostic (1.77e-1)" "unprognostic (1.57e-3)" "unprognostic (7.29e-2)" "unprognostic (3.12e-2)" "unprognostic (2.03e-2)" "unprognostic (1.86e-1)" "unprognostic (1.30e-1)" "unprognostic (1.60e-1)" "unprognostic (5.24e-2)" "unprognostic (2.81e-1)" MCRIP1 "FAM195B, GRAN2, MCRIP" ENSG00000225663 "MAPK regulated corepressor interacting protein 1" C9JLW8 17 81822361-81833302 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 15.3;Bergmann glia: 22.6;Brain excitatory neurons: 22.6;Brain inhibitory neurons: 17.0;Distal convoluted tubule cells: 15.8;Late spermatids: 48.9;Loop of henle epithelial cells: 17.6;Oligodendrocyte progenitor cells: 21.2;Oligodendrocytes: 27.7;Other brain neurons: 26.9;Papillary tip epithelial cells: 18.1;Podocytes: 32.5;Proximal tubule cells: 25.5;Renal collecting duct intercalated cells: 17.9;Renal collecting duct principal cells: 15.0;Renal connecting tubule cells: 19.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045542 Approved Approved Cytosol NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" 13 Cytosol "HPA045542: " "unprognostic (2.50e-1)" "unprognostic (2.72e-2)" "unprognostic (1.53e-2)" "unprognostic (1.91e-1)" "unprognostic (2.76e-1)" "unprognostic (4.47e-1)" "unprognostic (1.74e-1)" "unprognostic (1.69e-2)" "unprognostic (1.48e-1)" "unprognostic (1.09e-1)" "unprognostic (8.05e-3)" "potential prognostic favorable (2.78e-4)" "potential prognostic unfavorable (3.75e-4)" "unprognostic (3.24e-2)" "unprognostic (4.22e-2)" "unprognostic (2.58e-2)" "unprognostic (5.84e-2)" "unprognostic (2.03e-1)" "unprognostic (4.00e-1)" "potential prognostic favorable (7.50e-4)" "unprognostic (1.80e-1)" "unprognostic (2.58e-2)" "unprognostic (5.05e-2)" "unprognostic (3.08e-2)" "unprognostic (2.53e-1)" "unprognostic (1.29e-2)" "unprognostic (3.39e-2)" "unprognostic (3.03e-1)" "unprognostic (4.06e-1)" MCRIP2 "C16orf14, FAM195A, MGC15416" ENSG00000172366 "MAPK regulated corepressor interacting protein 2" Q9BUT9 16 636817-648474 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 47.3;liver: 57.1" "Cell type enhanced" "Detected in many" "Colonocytes: 230.1;Cytotrophoblasts: 246.1;Enterocytes: 245.2;Hepatocytes: 236.3;Late primary spermatocytes: 261.9;Late spermatids: 994.4;Parietal cells: 190.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060363 Uncertain NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 23: Choroid plexus - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 9 "HPA060363: " "unprognostic (6.32e-2)" "unprognostic (1.72e-1)" "unprognostic (6.70e-2)" "unprognostic (4.93e-3)" "unprognostic (1.01e-1)" "unprognostic (7.71e-2)" "unprognostic (2.35e-1)" "unprognostic (1.97e-1)" "unprognostic (2.81e-1)" "unprognostic (1.72e-1)" "unprognostic (1.44e-1)" "unprognostic (1.55e-1)" "unprognostic (2.96e-2)" "unprognostic (1.42e-1)" "unprognostic (3.29e-2)" "unprognostic (1.99e-2)" "unprognostic (3.81e-1)" "unprognostic (9.01e-2)" "unprognostic (1.79e-1)" "unprognostic (1.16e-2)" "unprognostic (1.34e-1)" "unprognostic (6.72e-2)" "unprognostic (1.46e-2)" "unprognostic (1.56e-1)" "unprognostic (1.35e-3)" "unprognostic (2.30e-1)" "unprognostic (2.69e-1)" "unprognostic (7.24e-2)" MCRS1 "ICP22BP, INO80Q, MCRS2, MSP58, P78" ENSG00000187778 "Microspherule protein 1" Q96EZ8 12 49556544-49568145 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039057 Supported Supported Nucleoplasm NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 147 Nucleoplasm "HPA039057: " "unprognostic (1.54e-1)" "unprognostic (1.69e-2)" "unprognostic (4.12e-3)" "unprognostic (1.78e-2)" "unprognostic (2.61e-1)" "unprognostic (1.18e-1)" "unprognostic (6.22e-2)" "unprognostic (3.12e-2)" "unprognostic (3.07e-1)" "unprognostic (1.88e-1)" "potential prognostic favorable (2.84e-4)" "unprognostic (2.13e-1)" "unprognostic (7.46e-3)" "potential prognostic unfavorable (2.84e-5)" "unprognostic (2.10e-3)" "unprognostic (2.15e-3)" "unprognostic (1.91e-2)" "unprognostic (1.11e-1)" "unprognostic (7.94e-2)" "unprognostic (2.26e-1)" "unprognostic (5.43e-2)" "unprognostic (2.59e-1)" "unprognostic (6.15e-2)" "unprognostic (4.74e-2)" "unprognostic (2.85e-2)" "unprognostic (3.95e-2)" "unprognostic (1.82e-2)" "unprognostic (1.80e-1)" "unprognostic (1.33e-1)" "unprognostic (1.45e-1)" "unprognostic (8.06e-2)" MCTP1 FLJ22344 ENSG00000175471 "Multiple C2 and transmembrane domain containing 1" Q6DN14 5 94703690-95285094 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 42.8" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 850.1;Brain inhibitory neurons: 629.8;cDC: 549.5;Macrophages: 700.2;Mast cells: 529.1;Monocyte progenitors: 674.6;monocytes: 1181.2;Neutrophil progenitors: 1058.0;Neutrophils: 5168.8;Vascular endothelial cells: 1397.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 45 "basophil: 37.1;classical monocyte: 28.7;eosinophil: 13.3;intermediate monocyte: 41.4;myeloid DC: 22.3;neutrophil: 40.7;non-classical monocyte: 40.8;plasmacytoid DC: 11.5" "Group enriched" "Detected in many" 54 "dendritic cells: 22.3;granulocytes: 40.7;monocytes: 41.4" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Minor Salivary Gland - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075887 Approved "Golgi apparatus" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 31: Non-specific - Transcription" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" "Golgi apparatus" "HPA075887: " "unprognostic (1.28e-1)" "unprognostic (2.15e-1)" "unprognostic (1.20e-1)" "potential prognostic unfavorable (4.88e-4)" "unprognostic (2.50e-2)" "unprognostic (1.66e-1)" "unprognostic (5.07e-3)" "unprognostic (1.45e-1)" "unprognostic (1.95e-1)" "unprognostic (1.11e-1)" "unprognostic (3.14e-3)" "unprognostic (1.85e-1)" "unprognostic (1.25e-3)" "unprognostic (3.54e-2)" "unprognostic (9.38e-2)" "unprognostic (9.09e-2)" "unprognostic (9.58e-2)" "unprognostic (2.00e-3)" "unprognostic (1.56e-1)" "unprognostic (9.76e-3)" "unprognostic (3.52e-2)" "unprognostic (1.91e-1)" "unprognostic (4.28e-2)" "unprognostic (1.53e-1)" "unprognostic (1.08e-1)" "unprognostic (4.16e-2)" "unprognostic (1.06e-1)" "unprognostic (2.50e-2)" "unprognostic (2.26e-1)" "unprognostic (1.10e-3)" "unprognostic (8.34e-3)" MCTP2 "FLJ11175, FLJ33303" ENSG00000140563 "Multiple C2 and transmembrane domain containing 2" Q6DN12 15 94231538-94483952 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 19.6" "Cell type enhanced" "Detected in many" "Hematopoietic stem cells: 794.3;Mast cells: 603.1;Mesothelial cells: 621.5;Neutrophil progenitors: 1213.4;Neutrophils: 4073.1;NK-cells: 1094.8" "Cell type enhanced" "Detected in many" "fibroblast: 177.1;leukocyte: 411.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 30.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Prostate - Prostate basal glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA051176, HPA070541" Uncertain Enhanced Nucleoplasm,Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 23: Choroid plexus - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 24: Neutrophils - Innate immunity signal integration" "Nucleoplasm, Cytosol" "HPA051176: , HPA070541: " "unprognostic (3.45e-1)" "unprognostic (5.80e-2)" "unprognostic (7.44e-2)" "unprognostic (1.97e-3)" "unprognostic (3.49e-1)" "unprognostic (4.63e-2)" "unprognostic (3.22e-2)" "unprognostic (4.33e-1)" "unprognostic (5.65e-2)" "unprognostic (7.13e-2)" "unprognostic (1.21e-1)" "unprognostic (1.56e-3)" "unprognostic (1.96e-2)" "unprognostic (1.43e-2)" "unprognostic (1.67e-1)" "unprognostic (1.51e-1)" "unprognostic (2.11e-1)" "unprognostic (2.24e-1)" "unprognostic (2.72e-2)" "unprognostic (2.41e-1)" "unprognostic (9.03e-2)" "unprognostic (6.76e-3)" "unprognostic (6.16e-2)" "unprognostic (1.61e-1)" "unprognostic (1.61e-1)" "unprognostic (1.47e-1)" "unprognostic (2.32e-3)" "unprognostic (1.19e-2)" MCTS1 MCT-1 ENSG00000232119 "MCTS1 re-initiation and release factor" Q9ULC4 X 120594010-120621159 "Predicted intracellular proteins" "Cell cycle, DNA damage, Growth regulation, Protein biosynthesis, Transcription, Transcription regulation" "Initiation factor" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 232.5;Esophageal suprabasal cells: 153.1;Extravillous trophoblasts: 191.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001045 Supported "Plasma membrane,Cytosol" NA NA 100000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 8: Non-specific - Secretory pathway" 6 Cytosol "Plasma membrane" "HPA001045: " "unprognostic (1.20e-2)" "potential prognostic unfavorable (1.07e-5)" "unprognostic (2.27e-1)" "unprognostic (7.78e-3)" "unprognostic (4.41e-2)" "unprognostic (1.24e-1)" "unprognostic (1.97e-3)" "unprognostic (8.08e-2)" "potential prognostic unfavorable (5.43e-5)" "unprognostic (1.47e-1)" "validated prognostic unfavorable (6.91e-5)" "validated prognostic unfavorable (3.68e-8)" "unprognostic (1.28e-2)" "unprognostic (2.16e-2)" "unprognostic (4.90e-2)" "unprognostic (5.27e-3)" "unprognostic (2.46e-3)" "unprognostic (3.64e-2)" "unprognostic (7.13e-2)" "unprognostic (1.96e-1)" "unprognostic (3.29e-2)" "unprognostic (3.85e-2)" "unprognostic (1.09e-1)" "unprognostic (1.23e-1)" "unprognostic (2.61e-2)" "unprognostic (2.40e-1)" "unprognostic (8.12e-2)" "unprognostic (1.49e-1)" "unprognostic (1.87e-1)" "unprognostic (4.86e-3)" "unprognostic (8.59e-2)" MCTS2 "MCTS2P, psiMCT-1" ENSG00000101898 "MCTS family member 2" A0A3B3IRV3 20 31547379-31548081 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" HPA001045 Approved "Plasma membrane,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 62: Non-specific - Plasma proteins" Cytosol "Plasma membrane" "HPA001045: " "unprognostic (4.65e-2)" "unprognostic (1.20e-2)" "unprognostic (1.33e-1)" "unprognostic (4.28e-2)" "unprognostic (9.22e-2)" "unprognostic (3.84e-2)" "unprognostic (2.23e-1)" "unprognostic (3.63e-2)" "unprognostic (7.49e-3)" "unprognostic (9.53e-2)" "unprognostic (1.98e-2)" "unprognostic (1.72e-1)" "unprognostic (2.12e-1)" "unprognostic (3.23e-2)" "potential prognostic favorable (1.78e-5)" "unprognostic (2.57e-1)" "unprognostic (4.52e-1)" "unprognostic (3.43e-2)" "unprognostic (2.85e-1)" MCU "C10orf42, CCDC109A, FLJ46135" ENSG00000156026 "Mitochondrial calcium uniporter" Q8NE86 10 72692143-72887694 "Predicted intracellular proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 51.2" "Cell type enhanced" "Detected in many" "Foveolar cells: 945.3;Myonuclei: 1130.9;Neutrophil progenitors: 1471.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Endothelial cells, Stomach - Gastric mucous cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016480 Approved Supported Mitochondria No No 37000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - DNA binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 15 Mitochondria "HPA016480: " "unprognostic (1.81e-2)" "unprognostic (4.86e-2)" "unprognostic (1.15e-1)" "unprognostic (1.86e-2)" "potential prognostic unfavorable (2.26e-4)" "unprognostic (3.53e-1)" "potential prognostic favorable (1.65e-5)" "unprognostic (2.62e-1)" "potential prognostic unfavorable (9.86e-4)" "potential prognostic favorable (1.99e-7)" "unprognostic (7.06e-2)" "unprognostic (4.12e-1)" "unprognostic (3.17e-2)" "unprognostic (3.32e-2)" "unprognostic (6.42e-2)" "unprognostic (2.66e-1)" "unprognostic (9.85e-3)" "unprognostic (8.80e-2)" "unprognostic (2.45e-2)" "unprognostic (1.14e-1)" "unprognostic (1.19e-2)" "unprognostic (1.07e-1)" "unprognostic (1.42e-1)" "unprognostic (4.74e-3)" "unprognostic (1.35e-2)" "unprognostic (2.84e-2)" "unprognostic (7.80e-2)" "unprognostic (3.97e-1)" "unprognostic (1.77e-1)" "unprognostic (3.26e-2)" MCUB "CCDC109B, FLJ20647" ENSG00000005059 "Mitochondrial calcium uniporter dominant negative subunit beta" Q9NWR8 4 109560209-109688719 "Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 30.1" "Cell type enhanced" "Detected in many" "B-cells: 141.7;Cytotrophoblasts: 195.9;Epicardial cells: 191.0;Hofbauer cells: 153.3;monocytes: 155.2;Retinal bipolar cells: 156.7;T-cells: 169.8" "Cell type enhanced" "Detected in many" "leukocyte: 161.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA014058, HPA048776" Enhanced Supported Mitochondria,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 39: Astrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 9: T-cells - Adaptive immunity: Regulation" 3 Mitochondria Cytosol "HPA014058: , HPA048776: " "unprognostic (9.67e-2)" "unprognostic (1.37e-2)" "unprognostic (2.23e-1)" "unprognostic (8.60e-2)" "unprognostic (4.76e-2)" "unprognostic (8.91e-2)" "potential prognostic unfavorable (5.11e-4)" "unprognostic (1.21e-1)" "unprognostic (1.52e-3)" "unprognostic (4.23e-3)" "unprognostic (1.24e-1)" "unprognostic (1.77e-1)" "unprognostic (3.63e-3)" "unprognostic (1.51e-2)" "unprognostic (1.92e-3)" "unprognostic (3.01e-2)" "potential prognostic unfavorable (2.61e-4)" "unprognostic (1.43e-1)" "unprognostic (2.27e-1)" "unprognostic (7.67e-3)" "unprognostic (6.78e-2)" "unprognostic (2.65e-1)" "unprognostic (9.75e-3)" "unprognostic (6.48e-2)" "unprognostic (3.12e-1)" "unprognostic (1.41e-1)" "unprognostic (4.51e-2)" "unprognostic (1.13e-1)" "unprognostic (3.09e-3)" MCUR1 "C6orf79, CCDC90A, FLJ20958" ENSG00000050393 "Mitochondrial calcium uniporter regulator 1" Q96AQ8 6 13786557-13814568 "Predicted intracellular proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 75.6" "Cell type enhanced" "Detected in many" "Breast lactating cells: 238.5;Esophageal apical cells: 639.3;Platelets: 317.4;Rod photoreceptor cells: 517.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078654 Approved NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 79: Photoreceptor cells - Phototransduction" 7 "HPA078654: " "unprognostic (8.62e-2)" "unprognostic (7.58e-3)" "unprognostic (3.05e-2)" "unprognostic (1.77e-2)" "unprognostic (2.71e-1)" "unprognostic (2.99e-2)" "unprognostic (9.96e-3)" "unprognostic (3.82e-2)" "unprognostic (3.11e-2)" "unprognostic (4.05e-3)" "unprognostic (7.30e-2)" "unprognostic (1.72e-1)" "unprognostic (1.04e-2)" "unprognostic (1.78e-1)" "unprognostic (1.36e-1)" "unprognostic (4.31e-2)" "unprognostic (2.18e-2)" "unprognostic (1.13e-3)" "unprognostic (3.16e-2)" "unprognostic (9.81e-2)" "unprognostic (1.53e-1)" "unprognostic (9.93e-2)" "unprognostic (1.58e-1)" "unprognostic (1.71e-1)" "unprognostic (5.82e-3)" "unprognostic (4.37e-2)" "unprognostic (3.38e-1)" "unprognostic (1.75e-1)" "unprognostic (2.52e-1)" MDC1 "Em:AB023051.5, KIAA0170, NFBD1" ENSG00000137337 "Mediator of DNA damage checkpoint 1" Q14676 6 30699807-30717447 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 15.3;Bergmann glia: 19.8;Distal convoluted tubule cells: 15.7;Ependymal cells: 13.0;Loop of henle epithelial cells: 21.8;Microglia: 13.6;Oligodendrocyte progenitor cells: 17.9;Oligodendrocytes: 13.9;Podocytes: 15.7;Proximal tubule cells: 19.9;Renal collecting duct intercalated cells: 19.5;Renal collecting duct principal cells: 19.8;Renal connecting tubule cells: 19.2;Tuft cells: 23.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "NK-cell: 3.2" "Lineage enriched" "Detected in single" 4 "NK-cells: 3.2" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006915, CAB080094, CAB080116" Enhanced Supported "Nucleoplasm,Nuclear bodies" No No "Cluster 24: Non-specific - Transcription" "Cluster 39: Testis - Nuclear processes" "Cluster 6: Non-specific - Immune response" "Cluster 28: Non-specific - Nuclear processes" "Cluster 102: Non-specific - Mixed function" 87 "Nucleoplasm, Nuclear bodies" "CAB080094: , CAB080116: , HPA006915: " "unprognostic (1.67e-1)" "unprognostic (1.32e-1)" "unprognostic (3.66e-1)" "unprognostic (1.25e-2)" "unprognostic (1.44e-1)" "unprognostic (1.21e-1)" "unprognostic (7.46e-2)" "unprognostic (3.76e-1)" "unprognostic (1.95e-1)" "unprognostic (1.39e-3)" "unprognostic (1.45e-2)" "potential prognostic favorable (6.14e-4)" "unprognostic (1.09e-1)" "unprognostic (1.21e-3)" "unprognostic (3.80e-2)" "unprognostic (1.74e-1)" "unprognostic (2.49e-2)" "unprognostic (4.30e-1)" "unprognostic (1.97e-2)" "unprognostic (1.71e-1)" "unprognostic (2.29e-2)" "unprognostic (7.57e-2)" "potential prognostic unfavorable (9.90e-4)" "unprognostic (3.58e-1)" "unprognostic (6.32e-3)" "unprognostic (2.17e-2)" "unprognostic (1.30e-2)" "unprognostic (1.49e-1)" "unprognostic (1.52e-1)" "unprognostic (1.62e-2)" "unprognostic (2.09e-1)" MDFI I-mfa ENSG00000112559 "MyoD family inhibitor" Q99750 6 41636882-41654244 "Predicted intracellular proteins" Differentiation "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 272.0;Esophageal apical cells: 203.5;Esophageal basal cells: 48.0;Esophageal suprabasal cells: 56.8;Extravillous trophoblasts: 146.0;Migrating cytotrophoblasts: 184.9;Syncytiotrophoblasts: 130.8" "Group enriched" "Detected in some" 6 "committed oligodendrocyte precursor: 61.8;fibroblast: 34.3;pericyte: 16.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 126.1" "Minor Salivary Gland - Minor salivary gland basal cells, Skeletal muscle - Fibroblasts" "Region enriched" "Detected in many" 7 "cerebellum: 17.0" "Low region specificity" "Detected in all" HPA049973 Approved Approved Nucleoplasm NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 347 Nucleoplasm "HPA049973: " "unprognostic (4.37e-1)" "unprognostic (1.21e-2)" "unprognostic (8.44e-2)" "unprognostic (1.88e-2)" "unprognostic (7.68e-3)" "unprognostic (2.83e-2)" "unprognostic (2.41e-2)" "unprognostic (3.19e-1)" "unprognostic (1.07e-1)" "unprognostic (2.14e-3)" "unprognostic (6.59e-2)" "potential prognostic favorable (4.76e-4)" "unprognostic (2.91e-3)" "unprognostic (1.43e-1)" "unprognostic (5.43e-1)" "potential prognostic unfavorable (5.22e-5)" "unprognostic (8.30e-3)" "unprognostic (1.05e-2)" "unprognostic (1.05e-1)" "unprognostic (4.83e-2)" "unprognostic (5.78e-3)" "unprognostic (1.29e-3)" "unprognostic (1.93e-2)" "unprognostic (4.52e-1)" "unprognostic (3.30e-1)" "unprognostic (8.45e-2)" "potential prognostic unfavorable (3.71e-4)" "unprognostic (3.41e-2)" "unprognostic (1.32e-1)" "unprognostic (2.09e-2)" "unprognostic (1.62e-2)" MDFIC "HIC, MDFIC1" ENSG00000135272 "MyoD family inhibitor domain containing" Q9P1T7 7 114922094-115019917 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction, Transcription, Transcription regulation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 614.0;Choroid plexus epithelial cells: 459.7;Innate lymphoid cells: 335.4;Lymphatic endothelial cells: 287.4;Myosatellite cells: 304.8;pDCs: 404.8;Podocytes: 239.5;T-cells: 288.2" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 402.2;leukocyte: 692.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030716 Approved Supported "Nucleoplasm,Golgi apparatus" "Intracellular and membrane" Transcription NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 8: Immune cells - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 89: Adipocytes - Lipid metabolism" 2 "Nucleoplasm, Golgi apparatus" "HPA030716: " "unprognostic (6.78e-3)" "unprognostic (2.22e-2)" "unprognostic (9.51e-2)" "unprognostic (1.51e-2)" "unprognostic (7.19e-2)" "unprognostic (1.01e-1)" "unprognostic (1.34e-1)" "unprognostic (1.05e-3)" "potential prognostic favorable (8.87e-4)" "unprognostic (1.15e-3)" "unprognostic (4.55e-3)" "unprognostic (2.06e-2)" "unprognostic (1.10e-1)" "unprognostic (3.64e-3)" "unprognostic (2.61e-2)" "unprognostic (4.51e-2)" "unprognostic (1.91e-2)" "unprognostic (3.18e-2)" "unprognostic (8.31e-2)" "unprognostic (1.67e-1)" "unprognostic (1.43e-1)" "unprognostic (2.95e-3)" "unprognostic (3.44e-2)" "unprognostic (1.88e-2)" "unprognostic (3.10e-2)" "unprognostic (1.57e-1)" "unprognostic (1.67e-1)" "unprognostic (5.15e-3)" "unprognostic (4.97e-2)" "unprognostic (2.37e-1)" "unprognostic (1.35e-2)" MDFIC2 ENSG00000242120 "MyoD family inhibitor domain containing 2" A0A1B0GVS7 3 70194479-70312638 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Endometrial glandular cells: 10.4;Endometrial luminal cells: 3.3;Epicardial cells: 4.5;Mesothelial cells: 3.9;Oligodendrocytes: 5.4;Oocytes: 4.6;Vascular smooth muscle cells: 3.1" "Group enriched" "Detected in some" 10 "medium spiny neuron: 4.9;oligodendrocyte: 17.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebral cortex: 4.2" "Region enhanced" "Detected in some" "hippocampal formation: 3.2" NA NA "Cluster 72: Neuronal - Signal transduction" "Cluster 51: Secretory epithelial cells - Mixed function" MDGA1 "GPIM, MAMDC3" ENSG00000112139 "MAM domain containing glycosylphosphatidylinositol anchor 1" Q8NFP4 6 37630679-37699306 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 17 "brain: 80.5" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 53.2;Brain excitatory neurons: 50.5;Cone photoreceptor cells: 60.0;Gonadotrophs: 45.7;Pituitary stem cells: 39.1;Retinal amacrine cells: 48.2;Retinal bipolar cells: 59.4;Retinal horizontal cells: 66.1" "Cell type enhanced" "Detected in all" "upper rhombic lip: 125.2" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 7 "cerebellum: 175.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Pituitary gland - Undifferentiated cells (Pituitary gland), Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031235, HPA050382" Enhanced Supported "Golgi apparatus,Plasma membrane" "Intracellular and membrane" "Developmental protein" NA NA 250000 "Cluster 71: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 3: Rhabdoid - Membrane components" "Cluster 2: Cerebellar granular cells - Neuronal signaling" "Plasma membrane" "Golgi apparatus" "HPA031235: , HPA050382: " "unprognostic (3.03e-2)" "unprognostic (4.45e-1)" "unprognostic (3.36e-2)" "unprognostic (8.17e-3)" "unprognostic (3.46e-1)" "unprognostic (6.81e-3)" "unprognostic (2.04e-1)" "unprognostic (2.59e-1)" "unprognostic (1.27e-2)" "potential prognostic unfavorable (5.88e-4)" "unprognostic (5.76e-2)" "unprognostic (2.99e-1)" "unprognostic (1.10e-1)" "unprognostic (8.82e-3)" "unprognostic (1.17e-1)" "unprognostic (3.13e-2)" "unprognostic (2.24e-1)" "unprognostic (4.65e-2)" "unprognostic (2.73e-1)" "unprognostic (2.10e-1)" "unprognostic (5.12e-2)" "unprognostic (1.74e-1)" "unprognostic (1.56e-1)" "unprognostic (5.71e-2)" "unprognostic (2.04e-2)" "unprognostic (6.59e-3)" "unprognostic (1.68e-1)" "unprognostic (5.04e-2)" MDGA2 MAMDC1 ENSG00000139915 "MAM domain containing glycosylphosphatidylinositol anchor 2" Q7Z553 14 46839629-47675605 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "brain: 3.4;retina: 4.1;testis: 3.5" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 1067.3;Brain inhibitory neurons: 1626.5;Breast lactating cells: 951.9;Oligodendrocyte progenitor cells: 2818.7;Oligodendrocytes: 766.7;Other brain neurons: 1785.0;Pituicytes/FSCs: 443.1;Retinal amacrine cells: 1150.8;Retinal bipolar cells: 2680.9;Retinal ganglion cells: 1104.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Skin Cutaneous Melanoma (TCGA): 1.9;Testicular Germ Cell Tumor (TCGA): 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 2.2" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003084 Uncertain NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 24: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "HPA003084: " "potential prognostic favorable (1.68e-5)" "unprognostic (5.39e-2)" "unprognostic (4.09e-1)" MDH1 ENSG00000014641 "Malate dehydrogenase 1" P40925 2 63588609-63607197 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1262.4;tongue: 1722.1" "Cell type enhanced" "Detected in all" "Hofbauer cells: 595.9;Parietal cells: 1030.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Smooth muscle cells, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Lung - Macrophages, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Stomach - Parietal cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027296, CAB047333, HPA054276" Uncertain Supported Centrosome,Cytosol NA NA 32000000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 7: Liver cancer - Metabolism" "Cluster 97: Non-specific - Cellular respiration" 16 "Centrosome, Cytosol" "CAB047333: , HPA027296: , HPA054276: " "unprognostic (1.01e-1)" "unprognostic (4.90e-2)" "unprognostic (2.43e-2)" "unprognostic (5.33e-3)" "unprognostic (9.06e-3)" "unprognostic (3.38e-2)" "unprognostic (1.76e-1)" "unprognostic (2.49e-2)" "unprognostic (5.36e-2)" "unprognostic (5.67e-3)" "unprognostic (2.36e-3)" "unprognostic (1.02e-1)" "unprognostic (1.33e-2)" "unprognostic (5.94e-2)" "potential prognostic unfavorable (4.52e-4)" "unprognostic (1.47e-3)" "unprognostic (2.60e-1)" "potential prognostic favorable (7.33e-4)" "unprognostic (1.19e-1)" "unprognostic (1.65e-1)" "unprognostic (2.47e-1)" "unprognostic (1.13e-1)" "unprognostic (2.54e-1)" "unprognostic (2.61e-1)" "unprognostic (1.18e-1)" "unprognostic (9.11e-2)" "unprognostic (2.22e-1)" "unprognostic (2.11e-1)" "unprognostic (3.40e-1)" "unprognostic (7.88e-2)" "unprognostic (1.80e-1)" MDH1B "FLJ25341, RP11-95H11" ENSG00000138400 "Malate dehydrogenase 1B" Q5I0G3 2 206737763-206765328 "Metabolic proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 19.8;fallopian tube: 21.2;testis: 22.9" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 42.9;Early spermatids: 159.2;Endometrial ciliated cells: 63.8;Ependymal cells: 79.1;Epididymal efferent duct ciliated cells: 60.0;Fallopian tube ciliated cells: 117.3;Late primary spermatocytes: 347.9;Respiratory ciliated cells: 127.1" "Cell type enhanced" "Detected in many" "ependymal cell: 89.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "choroid plexus: 32.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA073761 Approved NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" "HPA073761: " "unprognostic (2.69e-2)" "unprognostic (9.43e-3)" "unprognostic (2.75e-2)" "unprognostic (1.13e-2)" "unprognostic (8.66e-3)" "unprognostic (8.69e-2)" "unprognostic (1.87e-2)" "unprognostic (3.66e-2)" "unprognostic (8.34e-2)" "unprognostic (8.21e-2)" "unprognostic (8.72e-2)" "unprognostic (7.30e-2)" "unprognostic (2.26e-1)" "unprognostic (1.59e-1)" "unprognostic (4.02e-3)" "unprognostic (1.37e-1)" MDH2 ENSG00000146701 "Malate dehydrogenase 2" P40926 7 76048051-76067508 "Citric acid cycle related proteins, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" Oxidoreductase "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 652.9;tongue: 562.4" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 569.8;Esophageal basal cells: 563.5;Esophageal suprabasal cells: 690.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019714, HPA019716, HPA019848, HPA026720" Enhanced Enhanced Mitochondria No No 8100000 "Cluster 13: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cellular respiration" "Cluster 14: Neurons - Synaptic function" "Cluster 39: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 42 Mitochondria "HPA019714: , HPA019716: , HPA019848: , HPA026720: " "unprognostic (1.85e-1)" "unprognostic (5.60e-2)" "unprognostic (6.48e-2)" "unprognostic (1.52e-1)" "unprognostic (4.56e-3)" "unprognostic (7.76e-2)" "unprognostic (4.29e-3)" "unprognostic (7.59e-3)" "unprognostic (2.95e-2)" "unprognostic (1.16e-3)" "potential prognostic favorable (2.76e-4)" "unprognostic (2.45e-3)" "unprognostic (1.87e-3)" "unprognostic (6.77e-2)" "unprognostic (4.38e-3)" "unprognostic (2.46e-3)" "unprognostic (6.50e-2)" "unprognostic (1.17e-1)" "unprognostic (2.89e-1)" "unprognostic (6.69e-2)" "unprognostic (1.11e-1)" "unprognostic (1.26e-1)" "unprognostic (1.73e-1)" "unprognostic (6.93e-2)" "unprognostic (1.85e-2)" "unprognostic (2.54e-1)" "unprognostic (2.62e-1)" "unprognostic (1.84e-1)" "unprognostic (1.82e-2)" "unprognostic (4.40e-2)" "unprognostic (1.38e-2)" MDK "FLJ27379, MK, NEGF2" ENSG00000110492 Midkine P21741 11 46380756-46383837 "Cancer-related genes, Predicted secreted proteins" Differentiation "Developmental protein, Growth factor, Heparin-binding, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 571.9" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 1367.8;Enterocytes: 847.2;Gastric progenitor cells: 423.0;Granulosa cells: 1095.7;Neuroendocrine cells: 789.7;Ovarian stromal cells: 922.9" "Group enriched" "Detected in many" 5 "Bergmann glia: 65.8;endothelial cell: 36.2;fibroblast: 26.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.8;neutrophil: 2.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Pituitary gland - Gonadotropes, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010055, HPA057126" Uncertain Approved Vesicles "Secreted to blood" "Growth factor" NA NA 158000 53000000 "Cluster 75: Ovary - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 94: Gonadal somatic cells - Mixed function" 15 Vesicles "CAB010055: , HPA057126: " "unprognostic (1.40e-1)" "unprognostic (1.50e-2)" "unprognostic (9.38e-2)" "unprognostic (1.08e-1)" "unprognostic (4.41e-2)" "unprognostic (1.27e-1)" "validated prognostic unfavorable (3.34e-4)" "validated prognostic unfavorable (2.87e-4)" "unprognostic (2.93e-1)" "unprognostic (4.65e-3)" "potential prognostic unfavorable (2.47e-9)" "unprognostic (2.52e-1)" "unprognostic (1.62e-1)" "unprognostic (1.66e-2)" "unprognostic (6.23e-2)" "unprognostic (8.12e-2)" "unprognostic (1.17e-3)" "unprognostic (3.73e-2)" "unprognostic (3.13e-1)" "unprognostic (2.36e-2)" "unprognostic (6.16e-2)" "unprognostic (3.78e-2)" "unprognostic (3.07e-1)" "unprognostic (3.69e-1)" "unprognostic (2.32e-1)" "unprognostic (1.45e-1)" "unprognostic (2.71e-2)" "unprognostic (1.88e-1)" "unprognostic (1.16e-1)" "unprognostic (2.12e-1)" "unprognostic (3.84e-2)" MDM1 ENSG00000111554 "Mdm1 nuclear protein" Q8TC05 12 68272443-68332381 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 118.5;Ependymal cells: 80.4;Megakaryocytes: 98.9;Pituitary stem cells: 69.2;Respiratory ciliated cells: 75.4" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 118.0;ependymal cell: 107.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040411, HPA041594" Uncertain Approved "Centriolar satellite,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 5: Rhabdoid - Unknown function" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 3 "Centriolar satellite, Cytosol" "HPA040411: , HPA041594: " "unprognostic (1.61e-1)" "unprognostic (1.88e-1)" "unprognostic (7.66e-2)" "unprognostic (2.00e-1)" "unprognostic (2.42e-1)" "unprognostic (1.06e-1)" "unprognostic (4.96e-1)" "unprognostic (6.78e-2)" "unprognostic (2.06e-3)" "potential prognostic unfavorable (3.20e-4)" "unprognostic (1.66e-2)" "unprognostic (2.43e-1)" "unprognostic (7.17e-2)" "unprognostic (6.17e-3)" "unprognostic (1.04e-1)" "unprognostic (3.14e-1)" "unprognostic (9.41e-2)" "unprognostic (1.71e-1)" "unprognostic (3.26e-2)" "unprognostic (6.33e-3)" "unprognostic (1.59e-1)" "unprognostic (1.08e-1)" "unprognostic (1.22e-1)" "unprognostic (1.70e-1)" "unprognostic (3.21e-2)" "unprognostic (6.74e-3)" "unprognostic (2.41e-2)" "unprognostic (1.26e-2)" "unprognostic (4.44e-1)" "unprognostic (3.51e-2)" "unprognostic (1.72e-1)" MDM2 "HDM2, MGC5370" ENSG00000135679 "MDM2 proto-oncogene" Q00987 12 68808177-68845544 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Ubl conjugation pathway" Transferase "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial ciliated cells: 661.7;Neutrophils: 371.8;Thymic myoid cells: 1042.8;Urothelial cells: 760.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000086, CAB016303, HPA045159, CAB079977" Supported Supported "Nucleoplasm,Centriolar satellite,Cytosol,Mid piece,Principal piece,End piece" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 6: Leukemia - Signal transduction" "Cluster 69: Urothelial cells - Basic cellular functions" 369 "Nucleoplasm, Cytosol" "Centriolar satellite, Mid piece, Principal piece, End piece" "CAB000086: , CAB016303: , CAB079977: , HPA045159: " "unprognostic (9.41e-2)" "unprognostic (6.79e-2)" "unprognostic (7.07e-2)" "unprognostic (1.74e-2)" "unprognostic (5.81e-2)" "unprognostic (1.53e-2)" "unprognostic (6.28e-2)" "potential prognostic unfavorable (3.17e-4)" "unprognostic (2.30e-1)" "unprognostic (6.72e-2)" "potential prognostic favorable (4.89e-5)" "unprognostic (3.36e-3)" "unprognostic (1.27e-1)" "unprognostic (1.03e-1)" "unprognostic (3.75e-2)" "unprognostic (2.28e-1)" "unprognostic (1.43e-1)" "unprognostic (9.98e-2)" "unprognostic (4.24e-3)" "unprognostic (6.18e-3)" "unprognostic (5.90e-2)" "validated prognostic unfavorable (3.14e-4)" "validated prognostic unfavorable (2.89e-5)" "unprognostic (1.67e-1)" "unprognostic (1.47e-1)" "unprognostic (3.23e-3)" "unprognostic (3.73e-3)" "unprognostic (8.38e-3)" "unprognostic (4.32e-1)" "unprognostic (3.24e-1)" "unprognostic (1.78e-2)" MDM4 "HDMX, MDMX" ENSG00000198625 "MDM4 regulator of p53" O15151 1 204516379-204558120 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018919, HPA048821" Approved Supported Nucleoplasm NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 45: Non-specific - Nuclear processes" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 65 Nucleoplasm "HPA018919: , HPA048821: " "unprognostic (2.49e-3)" "unprognostic (3.10e-1)" "unprognostic (2.16e-1)" "unprognostic (2.34e-2)" "unprognostic (1.06e-2)" "unprognostic (3.12e-1)" "unprognostic (3.81e-1)" "unprognostic (1.14e-1)" "unprognostic (6.97e-3)" "unprognostic (3.89e-2)" "unprognostic (9.38e-3)" "unprognostic (2.84e-2)" "unprognostic (1.86e-1)" "unprognostic (4.50e-2)" "unprognostic (9.76e-2)" "unprognostic (5.41e-2)" "unprognostic (1.31e-1)" "unprognostic (2.23e-1)" "unprognostic (6.67e-3)" "unprognostic (1.83e-1)" "unprognostic (2.33e-1)" "unprognostic (1.15e-1)" "unprognostic (2.66e-3)" "potential prognostic unfavorable (9.33e-4)" "unprognostic (9.35e-2)" "unprognostic (1.03e-2)" "unprognostic (4.42e-3)" "unprognostic (3.51e-1)" "unprognostic (1.59e-1)" "unprognostic (1.56e-2)" "unprognostic (2.41e-2)" MDN1 "KIAA0301, Rea1" ENSG00000112159 "Midasin AAA ATPase 1" Q9NU22 6 89642498-89819794 "Essential proteins, Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Erythrocyte progenitors: 236.5" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 8.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029666, HPA029667, HPA029668, HPA029669" Uncertain Approved "Nucleoplasm,Nucleoli,Intermediate filaments,Cytosol" NA NA "Cluster 64: Non-specific - Transcription" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 21 "Nucleoli, Cytosol" "Nucleoplasm, Intermediate filaments" "HPA029666: , HPA029667: , HPA029668: , HPA029669: " "unprognostic (2.17e-1)" "unprognostic (1.35e-1)" "unprognostic (2.43e-1)" "unprognostic (1.43e-2)" "unprognostic (9.17e-2)" "unprognostic (1.01e-1)" "unprognostic (4.73e-3)" "unprognostic (2.58e-2)" "unprognostic (1.86e-1)" "validated prognostic favorable (1.89e-5)" "validated prognostic favorable (7.73e-4)" "unprognostic (2.35e-1)" "unprognostic (2.52e-1)" "unprognostic (2.06e-1)" "unprognostic (1.18e-1)" "unprognostic (5.73e-2)" "unprognostic (3.91e-2)" "unprognostic (3.86e-1)" "unprognostic (2.84e-3)" "unprognostic (4.41e-2)" "unprognostic (5.41e-3)" "unprognostic (1.68e-1)" "unprognostic (3.18e-3)" "potential prognostic favorable (1.06e-4)" "unprognostic (4.50e-1)" "unprognostic (6.37e-2)" "unprognostic (1.73e-1)" "unprognostic (1.64e-1)" "unprognostic (2.50e-1)" MDP1 "FN6Pase, MGC5987" ENSG00000213920 "Magnesium dependent phosphatase 1" Q86V88 14 24213943-24216070 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 11 "vascular associated smooth muscle cell: 1.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "HPA003064, HPA070338" Uncertain Approved Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 1 Nucleoplasm "HPA003064: , HPA070338: " "unprognostic (2.26e-2)" "unprognostic (7.72e-2)" "unprognostic (2.46e-2)" "unprognostic (1.16e-2)" "unprognostic (8.74e-2)" "unprognostic (5.42e-2)" "unprognostic (8.65e-2)" "unprognostic (1.38e-2)" "unprognostic (1.07e-1)" "unprognostic (2.42e-2)" "potential prognostic favorable (6.49e-4)" "unprognostic (1.38e-1)" "unprognostic (6.11e-2)" "unprognostic (1.46e-1)" "unprognostic (9.10e-3)" "unprognostic (1.09e-1)" "unprognostic (2.19e-3)" "unprognostic (5.08e-2)" "unprognostic (4.47e-1)" "unprognostic (2.97e-2)" "unprognostic (2.43e-1)" "unprognostic (8.29e-3)" "unprognostic (2.74e-1)" "unprognostic (4.06e-3)" "unprognostic (4.89e-2)" "unprognostic (3.09e-1)" "unprognostic (9.72e-2)" "potential prognostic unfavorable (1.22e-4)" "unprognostic (8.78e-3)" "unprognostic (3.84e-1)" "unprognostic (2.07e-1)" ME1 ENSG00000065833 "Malic enzyme 1" P48163 6 83210402-83431051 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 398.3;Esophageal apical cells: 346.8;Kupffer cells: 530.9;Müller glia: 253.4;Sertoli cells: 535.9" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Lung Squamous Cell Carcinoma (TCGA): 41.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "MAIT T-cell: 16.0" "Lineage enriched" "Detected in many" 10 "T-cells: 16.0" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Pituitary gland - Thyrotropes, Prostate - Smooth muscle cells, Spleen - Macrophages, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006493 Enhanced Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA 3000000 "Cluster 1: T-cells - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 7: Liver cancer - Metabolism" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 3 "Nucleoplasm, Plasma membrane" Cytosol "HPA006493: " "unprognostic (4.81e-2)" "unprognostic (5.56e-2)" "unprognostic (2.38e-1)" "unprognostic (6.96e-3)" "unprognostic (1.85e-1)" "unprognostic (5.20e-2)" "unprognostic (9.14e-3)" "unprognostic (6.19e-3)" "unprognostic (3.40e-3)" "unprognostic (2.19e-1)" "unprognostic (1.05e-1)" "unprognostic (2.10e-2)" "potential prognostic unfavorable (1.06e-4)" "potential prognostic unfavorable (1.54e-4)" "unprognostic (1.74e-1)" "unprognostic (1.03e-1)" "unprognostic (2.16e-1)" "unprognostic (4.31e-1)" "unprognostic (1.30e-1)" "unprognostic (2.25e-2)" "unprognostic (1.32e-1)" "unprognostic (1.02e-2)" "unprognostic (1.83e-1)" "unprognostic (1.45e-1)" "unprognostic (3.00e-1)" "unprognostic (6.21e-2)" "potential prognostic unfavorable (8.59e-4)" "unprognostic (2.63e-2)" "unprognostic (4.07e-1)" "unprognostic (2.97e-2)" "unprognostic (4.94e-3)" ME2 ENSG00000082212 "Malic enzyme 2" P23368 18 50879080-50954257 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Allosteric enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 86.4" "Cell type enhanced" "Detected in all" "Choroid plexus epithelial cells: 392.8;Kupffer cells: 289.0;Rod photoreceptor cells: 298.5;Thymic myoid cells: 247.5" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 405.4" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "choroid plexus: 107.9" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008247, HPA008880" Enhanced Supported Mitochondria NA NA 230000 "Cluster 25: Non-specific - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 6 Mitochondria "HPA008247: , HPA008880: " "unprognostic (2.19e-2)" "unprognostic (3.54e-2)" "unprognostic (1.76e-1)" "unprognostic (1.39e-3)" "potential prognostic favorable (5.70e-4)" "unprognostic (1.05e-1)" "unprognostic (1.67e-1)" "unprognostic (1.29e-1)" "unprognostic (1.67e-1)" "potential prognostic unfavorable (9.04e-4)" "potential prognostic favorable (5.29e-4)" "unprognostic (2.41e-1)" "unprognostic (2.98e-1)" "potential prognostic unfavorable (1.03e-7)" "unprognostic (6.15e-3)" "unprognostic (3.07e-1)" "unprognostic (2.15e-2)" "unprognostic (3.95e-1)" "unprognostic (2.01e-2)" "unprognostic (1.45e-1)" "unprognostic (1.91e-1)" "unprognostic (2.11e-1)" "unprognostic (1.05e-1)" "unprognostic (2.57e-2)" "unprognostic (1.98e-1)" "unprognostic (1.30e-2)" "unprognostic (3.40e-1)" "unprognostic (8.26e-2)" "unprognostic (2.27e-1)" "unprognostic (1.80e-1)" "unprognostic (2.70e-1)" ME3 ENSG00000151376 "Malic enzyme 3" Q16798 11 86441108-86672636 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 217.1;Cardiomyocytes: 202.1;Distal convoluted tubule cells: 389.8;Gonadotrophs: 200.2;Retinal horizontal cells: 208.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 48.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Minor Salivary Gland - Smooth muscle cells, Skeletal muscle - Fibroblasts, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038473 Approved NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 75: Ovary - Mixed function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" "HPA038473: " "unprognostic (1.89e-1)" "unprognostic (5.51e-3)" "unprognostic (5.34e-2)" "unprognostic (3.30e-1)" "unprognostic (1.46e-1)" "unprognostic (4.38e-3)" "unprognostic (1.92e-1)" "potential prognostic favorable (2.21e-4)" "unprognostic (9.46e-2)" "unprognostic (1.31e-2)" "unprognostic (1.61e-1)" "unprognostic (1.40e-3)" "unprognostic (3.84e-2)" "unprognostic (3.16e-2)" "unprognostic (1.56e-1)" "unprognostic (1.37e-2)" "unprognostic (3.16e-2)" "unprognostic (5.97e-3)" "unprognostic (8.90e-2)" "unprognostic (7.12e-2)" "unprognostic (1.24e-1)" "unprognostic (2.67e-1)" "unprognostic (3.01e-3)" "unprognostic (4.04e-2)" "unprognostic (1.10e-2)" "unprognostic (3.87e-1)" "unprognostic (1.24e-1)" "unprognostic (1.71e-1)" "unprognostic (1.62e-1)" "unprognostic (8.44e-2)" "unprognostic (9.87e-2)" MEA1 MEA ENSG00000124733 "Male-enhanced antigen 1" Q16626 6 43011143-43016868 "Plasma proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Early spermatids: 795.5;Late primary spermatocytes: 753.1;Late spermatids: 2897.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017921, HPA073087" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 28: Non-specific - Nuclear processes" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 16 "Nucleoplasm, Cytosol" "HPA017921: , HPA073087: " "unprognostic (6.82e-2)" "unprognostic (5.72e-2)" "unprognostic (3.24e-2)" "unprognostic (9.63e-2)" "unprognostic (3.06e-1)" "unprognostic (1.15e-1)" "unprognostic (5.18e-3)" "unprognostic (6.25e-2)" "unprognostic (1.76e-1)" "unprognostic (2.50e-3)" "unprognostic (7.81e-2)" "unprognostic (1.10e-1)" "unprognostic (1.88e-1)" "unprognostic (2.07e-2)" "unprognostic (1.58e-3)" "unprognostic (9.74e-2)" "unprognostic (2.94e-2)" "unprognostic (3.74e-3)" "unprognostic (2.65e-1)" "potential prognostic favorable (4.20e-4)" "unprognostic (1.93e-1)" "unprognostic (3.67e-2)" "unprognostic (1.47e-1)" "unprognostic (1.55e-1)" "unprognostic (1.87e-1)" "unprognostic (2.63e-1)" "potential prognostic unfavorable (3.10e-4)" "unprognostic (4.89e-2)" "unprognostic (1.11e-1)" "unprognostic (2.44e-1)" "unprognostic (1.86e-2)" MEAF6 "C1orf149, CENP-28, Eaf6, FLJ11730, NY-SAR-91" ENSG00000163875 "MYST/Esa1 associated factor 6" Q9HAF1 1 37489993-37514766 "Disease related genes, Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 327.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029599 Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 73: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 37: Non-specific - mRNA processing" "Cluster 97: Non-specific - Cellular respiration" 46 "Nuclear bodies" Nucleoplasm "HPA029599: " "unprognostic (7.08e-2)" "unprognostic (2.36e-1)" "unprognostic (7.85e-2)" "unprognostic (1.97e-1)" "unprognostic (2.98e-1)" "unprognostic (4.21e-2)" "unprognostic (1.06e-1)" "unprognostic (1.40e-3)" "unprognostic (1.93e-2)" "potential prognostic unfavorable (9.48e-5)" "potential prognostic favorable (2.81e-7)" "unprognostic (2.86e-3)" "unprognostic (2.55e-1)" "unprognostic (4.55e-2)" "unprognostic (3.45e-2)" "unprognostic (5.91e-3)" "unprognostic (1.18e-1)" "unprognostic (1.00e-2)" "unprognostic (8.67e-2)" "unprognostic (1.41e-1)" "unprognostic (9.27e-2)" "unprognostic (9.34e-2)" "unprognostic (1.49e-1)" "unprognostic (4.40e-2)" "unprognostic (3.78e-3)" "unprognostic (5.61e-2)" "unprognostic (9.76e-2)" "unprognostic (2.08e-1)" "unprognostic (2.76e-1)" "unprognostic (1.40e-1)" "unprognostic (4.14e-2)" MEAK7 "KIAA1609, mEAK-7, TLDC1" ENSG00000140950 "MTOR associated protein, eak-7 homolog" Q6P9B6 16 84476355-84554033 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 149.0;Esophageal suprabasal cells: 76.5;Rod photoreceptor cells: 95.5;Syncytiotrophoblasts: 74.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041020 Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA 9600 "Cluster 42: Non-specific - Vesicular transport" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 24: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 79: Photoreceptor cells - Phototransduction" 4 Cytosol "Nucleoplasm, Nucleoli" "HPA041020: " "unprognostic (7.67e-2)" "unprognostic (6.30e-2)" "unprognostic (1.24e-1)" "unprognostic (1.52e-1)" "unprognostic (1.81e-1)" "unprognostic (7.64e-2)" "unprognostic (1.11e-1)" "unprognostic (1.06e-2)" "unprognostic (1.55e-1)" "unprognostic (7.96e-2)" "unprognostic (6.83e-2)" "unprognostic (9.14e-3)" "unprognostic (3.74e-3)" "unprognostic (4.46e-3)" "unprognostic (1.48e-2)" "potential prognostic unfavorable (1.83e-4)" "unprognostic (2.26e-3)" "unprognostic (1.46e-1)" "unprognostic (1.57e-1)" "validated prognostic unfavorable (4.60e-4)" "validated prognostic unfavorable (3.58e-7)" "unprognostic (7.14e-2)" "unprognostic (1.73e-1)" "unprognostic (3.37e-2)" "unprognostic (1.14e-1)" "unprognostic (2.59e-1)" "unprognostic (6.40e-2)" "unprognostic (7.82e-2)" "unprognostic (4.32e-2)" MECOM "EVI1, KMT8E, MDS1, MDS1-EVI1, PRDM3" ENSG00000085276 "MDS1 and EVI1 complex locus" Q03112 3 169083499-169663775 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Apoptosis, Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 69.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 1650.7;Distal convoluted tubule cells: 5676.7;Loop of henle epithelial cells: 3085.0;Mucous neck cells: 1848.9;Pancreatic acinar cells: 1684.5;Papillary tip epithelial cells: 2325.0;Pituicytes/FSCs: 2986.7;Renal collecting duct intercalated cells: 2595.9;Renal collecting duct principal cells: 4488.7;Renal connecting tubule cells: 6139.4;Transitional alveolar cells: 1936.3" "Cell type enriched" "Detected in many" 9 "endothelial cell: 3226.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.6" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Heart muscle - Endothelial cells, Liver - Vascular endothelial cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Prostate - Urothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Spleen - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046537 Supported Supported "Nuclear speckles" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 60: Stomach - Digestion" "Cluster 47: Endothelial cells - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 67 "Nuclear speckles" "HPA046537: " "unprognostic (4.90e-3)" "unprognostic (6.73e-3)" "unprognostic (3.14e-2)" "unprognostic (9.35e-2)" "unprognostic (1.38e-1)" "unprognostic (7.63e-2)" "unprognostic (2.88e-2)" "unprognostic (1.31e-2)" "unprognostic (3.82e-1)" "unprognostic (2.99e-2)" "unprognostic (2.01e-3)" "unprognostic (3.17e-3)" "unprognostic (8.66e-3)" "unprognostic (2.06e-2)" "unprognostic (1.86e-1)" "potential prognostic favorable (6.61e-4)" "unprognostic (1.17e-1)" "unprognostic (2.81e-1)" "unprognostic (3.67e-1)" "unprognostic (1.16e-2)" "unprognostic (2.03e-1)" "potential prognostic unfavorable (1.01e-4)" "unprognostic (7.24e-2)" "unprognostic (3.37e-1)" "unprognostic (9.32e-3)" "unprognostic (3.61e-1)" "unprognostic (8.48e-2)" "unprognostic (1.34e-1)" "unprognostic (1.07e-1)" "unprognostic (5.63e-2)" "unprognostic (8.99e-2)" MECP2 "MRX16, MRX79, RTT" ENSG00000169057 "Methyl-CpG binding protein 2" P51608 X 154021573-154137103 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Autism, Autism spectrum disorder, Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 604.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 48.3" "Lineage enriched" "Detected in all" 5 "granulocytes: 48.3" "Low cancer specificity" "Detected in all" "Pancreas - Endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000593, HPA001341, CAB037264" Enhanced Approved Nucleoplasm NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 36: Non-specific - mRNA processing" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 148 Nucleoplasm "CAB037264: , HPA000593: , HPA001341: " "unprognostic (4.84e-2)" "unprognostic (1.30e-3)" "unprognostic (1.69e-1)" "unprognostic (2.79e-2)" "unprognostic (7.67e-3)" "unprognostic (2.01e-2)" "unprognostic (1.52e-1)" "unprognostic (9.62e-2)" "unprognostic (3.07e-2)" "unprognostic (7.90e-2)" "potential prognostic favorable (2.33e-6)" "unprognostic (9.29e-3)" "unprognostic (2.04e-1)" "unprognostic (1.69e-2)" "unprognostic (7.44e-3)" "unprognostic (5.72e-2)" "unprognostic (8.37e-2)" "unprognostic (2.27e-1)" "unprognostic (8.88e-2)" "unprognostic (1.21e-1)" "unprognostic (1.43e-1)" "unprognostic (3.20e-1)" "unprognostic (5.33e-3)" "unprognostic (1.24e-1)" "unprognostic (3.03e-1)" "unprognostic (1.31e-1)" "unprognostic (1.60e-1)" "unprognostic (1.31e-1)" "unprognostic (5.39e-2)" "unprognostic (7.75e-3)" "unprognostic (4.77e-3)" MECR "CGI-63, ETR1, FASN2B, NRBF1" ENSG00000116353 "Mitochondrial trans-2-enoyl-CoA reductase" Q9BV79 1 29192657-29230942 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Disease variant, Dystonia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 184.2;Rod photoreceptor cells: 147.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022018, HPA022030, HPA028740" Enhanced Supported Mitochondria NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 24: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 79: Photoreceptor cells - Phototransduction" 3 Mitochondria "HPA022018: , HPA022030: , HPA028740: " "unprognostic (1.63e-1)" "unprognostic (1.95e-1)" "unprognostic (1.45e-3)" "unprognostic (6.93e-2)" "unprognostic (1.76e-1)" "unprognostic (8.03e-2)" "unprognostic (6.44e-2)" "unprognostic (1.06e-1)" "unprognostic (2.87e-1)" "unprognostic (3.76e-2)" "unprognostic (2.87e-1)" "unprognostic (3.86e-2)" "unprognostic (1.37e-2)" "unprognostic (2.23e-3)" "unprognostic (1.95e-1)" "unprognostic (5.09e-2)" "unprognostic (1.39e-1)" "unprognostic (1.03e-1)" "unprognostic (1.73e-1)" "unprognostic (9.46e-2)" "unprognostic (4.90e-2)" "unprognostic (6.63e-3)" "unprognostic (9.24e-2)" "unprognostic (4.54e-3)" "unprognostic (4.44e-1)" "unprognostic (2.18e-3)" "unprognostic (8.07e-2)" "unprognostic (2.11e-1)" "unprognostic (8.47e-3)" "unprognostic (1.11e-1)" "unprognostic (1.69e-1)" MED1 "CRSP1, CRSP200, DRIP230, PBP, PPARBP, PPARGBP, RB18A, TRAP220, TRIP2" ENSG00000125686 "Mediator complex subunit 1" Q15648 17 39404285-39451272 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017696, HPA052818" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 17: Non-specific - RNA processing" 154 Nucleoplasm Vesicles "CAB017696: , HPA052818: " "unprognostic (1.72e-1)" "unprognostic (8.47e-2)" "unprognostic (2.26e-1)" "unprognostic (8.96e-2)" "unprognostic (3.33e-1)" "unprognostic (1.05e-2)" "unprognostic (4.59e-2)" "unprognostic (5.58e-2)" "unprognostic (3.22e-1)" "potential prognostic unfavorable (1.02e-4)" "potential prognostic favorable (3.88e-4)" "unprognostic (1.62e-2)" "unprognostic (6.03e-2)" "potential prognostic unfavorable (8.50e-4)" "unprognostic (3.98e-2)" "unprognostic (3.41e-2)" "potential prognostic unfavorable (3.78e-5)" "unprognostic (1.46e-1)" "unprognostic (4.49e-2)" "potential prognostic unfavorable (1.24e-4)" "unprognostic (3.18e-2)" "unprognostic (1.45e-1)" "potential prognostic unfavorable (5.39e-5)" "unprognostic (3.27e-1)" "unprognostic (2.83e-3)" "unprognostic (1.22e-2)" "unprognostic (6.70e-2)" "unprognostic (3.30e-1)" "unprognostic (2.25e-1)" "unprognostic (5.97e-2)" "unprognostic (3.38e-1)" MED10 "L6, MGC5309, NUT2, TRG20" ENSG00000133398 "Mediator complex subunit 10" Q9BTT4 5 6371874-6378571 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042795, HPA054188" Enhanced Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 14: Neurons - Synaptic function" "Cluster 29: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 165 Nucleoplasm "HPA042795: , HPA054188: " "unprognostic (2.92e-1)" "unprognostic (2.68e-3)" "unprognostic (2.13e-1)" "unprognostic (3.16e-1)" "unprognostic (2.50e-2)" "unprognostic (2.34e-2)" "potential prognostic unfavorable (1.80e-6)" "unprognostic (2.99e-3)" "unprognostic (5.80e-2)" "unprognostic (1.54e-3)" "unprognostic (1.01e-1)" "unprognostic (5.17e-2)" "potential prognostic unfavorable (6.44e-4)" "potential prognostic unfavorable (1.91e-7)" "unprognostic (1.35e-3)" "unprognostic (1.43e-1)" "unprognostic (2.25e-3)" "unprognostic (5.90e-3)" "unprognostic (3.14e-2)" "unprognostic (2.70e-2)" "unprognostic (2.84e-1)" "unprognostic (2.45e-1)" "potential prognostic unfavorable (6.28e-4)" "unprognostic (5.93e-2)" "unprognostic (1.32e-1)" "unprognostic (3.24e-2)" "unprognostic (8.02e-2)" "unprognostic (7.16e-2)" "unprognostic (1.69e-1)" "unprognostic (2.10e-2)" "unprognostic (2.90e-1)" MED11 "HSPC296, MGC88387" ENSG00000161920 "Mediator complex subunit 11" Q9P086 17 4731428-4733608 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056669 Uncertain Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 76: Non-specific - Metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 42: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 132 "Nucleoplasm, Nuclear bodies" "HPA056669: " "unprognostic (8.14e-2)" "unprognostic (1.87e-1)" "unprognostic (7.08e-2)" "unprognostic (1.12e-1)" "unprognostic (5.05e-2)" "unprognostic (2.25e-3)" "unprognostic (1.32e-1)" "unprognostic (4.75e-2)" "unprognostic (4.10e-2)" "unprognostic (1.19e-2)" "unprognostic (4.60e-3)" "potential prognostic favorable (1.22e-4)" "potential prognostic favorable (4.87e-5)" "unprognostic (3.00e-1)" "unprognostic (1.91e-2)" "unprognostic (1.82e-1)" "unprognostic (4.42e-3)" "unprognostic (2.71e-1)" "unprognostic (1.48e-1)" "unprognostic (3.13e-2)" "unprognostic (1.66e-1)" "unprognostic (1.49e-2)" "unprognostic (8.94e-2)" "unprognostic (1.25e-1)" "unprognostic (2.56e-1)" "unprognostic (8.45e-3)" "unprognostic (7.50e-3)" "unprognostic (8.64e-3)" "unprognostic (1.77e-1)" "unprognostic (2.51e-1)" "unprognostic (1.79e-2)" MED12 "ARC240, CAGH45, FGS1, HOPA, KIAA0192, Kto, OKS, OPA1, TNRC11, TRAP230" ENSG00000184634 "Mediator complex subunit 12" Q93074 X 71118543-71144103 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Repressor" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 54.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003184, HPA003185" Enhanced Approved Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 43: Hindbrain - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 86 Nucleoplasm "HPA003184: , HPA003185: " "unprognostic (5.92e-2)" "unprognostic (4.88e-3)" "unprognostic (4.13e-2)" "unprognostic (6.89e-2)" "unprognostic (1.00e-1)" "unprognostic (1.04e-1)" "unprognostic (3.19e-2)" "unprognostic (7.55e-2)" "unprognostic (1.12e-1)" "unprognostic (2.01e-2)" "unprognostic (2.93e-1)" "unprognostic (9.58e-2)" "unprognostic (1.41e-1)" "unprognostic (8.16e-3)" "unprognostic (1.73e-1)" "unprognostic (2.59e-2)" "unprognostic (3.92e-3)" "unprognostic (4.78e-2)" "unprognostic (1.78e-2)" "unprognostic (1.54e-1)" "unprognostic (2.19e-2)" "unprognostic (2.46e-1)" "unprognostic (1.39e-1)" "unprognostic (1.50e-1)" "unprognostic (3.06e-1)" "unprognostic (4.41e-3)" "unprognostic (1.33e-1)" "unprognostic (2.09e-1)" "unprognostic (5.36e-2)" "unprognostic (1.12e-1)" "unprognostic (1.08e-2)" MED12L "KIAA1635, TNRC11L, TRALP, TRALPUSH" ENSG00000144893 "Mediator complex subunit 12L" Q86YW9 3 151085286-151437072 "Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Repressor" "Autism spectrum disorder, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 3.6;testis: 3.8" "Cell type enhanced" "Detected in many" "Astrocytes: 470.8;Choroid plexus epithelial cells: 1516.9;Ependymal cells: 409.7;Hematopoietic stem cells: 1036.4;Megakaryocyte progenitors: 2142.2;Megakaryocyte-Erythroid progenitors: 1069.2;Pituitary stem cells: 499.3" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 1326.0" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 2.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 1.0;plasmacytoid DC: 1.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036807 Uncertain Approved Nucleoli NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 23: Choroid plexus - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 40 Nucleoli "HPA036807: " "unprognostic (1.15e-1)" "unprognostic (5.99e-3)" "unprognostic (8.76e-2)" "potential prognostic favorable (8.55e-5)" "unprognostic (1.55e-1)" "unprognostic (2.87e-1)" MED13 "KIAA0593, THRAP1, TRAP240" ENSG00000108510 "Mediator complex subunit 13" Q9UHV7 17 61942605-62065278 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Repressor" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Myonuclei: 700.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067939 Supported Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 82 Nucleoplasm "HPA067939: " "unprognostic (5.06e-2)" "unprognostic (8.69e-2)" "unprognostic (1.52e-1)" "unprognostic (8.13e-3)" "unprognostic (1.62e-2)" "unprognostic (1.07e-2)" "unprognostic (6.15e-3)" "unprognostic (5.01e-2)" "unprognostic (3.17e-1)" "unprognostic (1.09e-2)" "potential prognostic favorable (9.37e-5)" "unprognostic (1.03e-2)" "unprognostic (2.09e-1)" "unprognostic (1.06e-1)" "unprognostic (1.01e-1)" "unprognostic (2.82e-2)" "unprognostic (4.66e-2)" "unprognostic (5.57e-3)" "unprognostic (3.91e-2)" "unprognostic (1.68e-1)" "unprognostic (2.00e-2)" "unprognostic (1.35e-1)" "unprognostic (1.25e-2)" "unprognostic (2.76e-2)" "unprognostic (4.15e-2)" "unprognostic (1.31e-2)" "unprognostic (5.50e-2)" "unprognostic (3.00e-1)" "unprognostic (1.97e-1)" "unprognostic (3.00e-2)" "unprognostic (2.74e-1)" MED13L "KIAA1025, THRAP2, TRAP240L" ENSG00000123066 "Mediator complex subunit 13L" Q71F56 12 115957905-116277693 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Repressor" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 2228.8;Neutrophils: 3813.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 3.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039445 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 24: Neutrophils - Innate immunity signal integration" 74 Nucleoplasm "Golgi apparatus" "HPA039445: " "unprognostic (2.85e-2)" "unprognostic (9.01e-2)" "unprognostic (1.18e-1)" "unprognostic (1.43e-1)" "unprognostic (1.88e-1)" "unprognostic (1.79e-2)" "unprognostic (7.50e-2)" "unprognostic (1.41e-3)" "unprognostic (1.73e-2)" "unprognostic (7.24e-2)" "potential prognostic favorable (1.01e-5)" "unprognostic (1.59e-3)" "unprognostic (3.34e-2)" "unprognostic (1.44e-1)" "unprognostic (4.21e-1)" "unprognostic (1.85e-2)" "unprognostic (1.03e-2)" "unprognostic (7.11e-2)" "unprognostic (9.10e-2)" "unprognostic (3.31e-3)" "unprognostic (1.08e-3)" "unprognostic (2.87e-2)" "unprognostic (4.15e-3)" "unprognostic (1.22e-1)" "unprognostic (2.38e-2)" "unprognostic (4.99e-3)" "unprognostic (2.80e-1)" "unprognostic (1.69e-1)" "unprognostic (1.50e-1)" "unprognostic (5.27e-3)" "unprognostic (7.57e-2)" MED14 "CRSP150, CRSP2, CSRP, CXorf4, EXLM1, RGR1, TRAP170" ENSG00000180182 "Mediator complex subunit 14" O60244 X 40648305-40735858 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 212.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027558 Approved "Nucleoplasm,Nuclear bodies,Vesicles" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 155 Nucleoplasm "Nuclear bodies, Vesicles" "HPA027558: " "unprognostic (2.75e-1)" "unprognostic (8.81e-2)" "unprognostic (1.41e-1)" "unprognostic (2.49e-1)" "unprognostic (6.90e-2)" "unprognostic (2.71e-2)" "unprognostic (3.41e-1)" "unprognostic (1.96e-1)" "unprognostic (2.31e-1)" "unprognostic (4.38e-2)" "potential prognostic favorable (2.17e-4)" "unprognostic (2.44e-1)" "unprognostic (2.87e-2)" "unprognostic (2.93e-3)" "unprognostic (4.35e-2)" "unprognostic (1.09e-2)" "unprognostic (1.01e-3)" "unprognostic (4.02e-1)" "unprognostic (3.08e-1)" "unprognostic (9.52e-2)" "unprognostic (2.52e-1)" "unprognostic (3.78e-2)" "unprognostic (1.48e-1)" "unprognostic (6.46e-2)" "unprognostic (3.92e-2)" "unprognostic (8.22e-2)" "unprognostic (2.91e-1)" "unprognostic (1.02e-1)" "unprognostic (2.57e-1)" "unprognostic (6.61e-2)" "unprognostic (6.78e-2)" MED15 "Arc105, CAG7A, PCQAP, TIG-1, TNRC7" ENSG00000099917 "Mediator complex subunit 15" Q96RN5 22 20495913-20587632 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003179 Approved Supported Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 66: Non-specific - Mitochondria" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 67 Nucleoplasm "HPA003179: " "unprognostic (3.22e-2)" "unprognostic (3.11e-1)" "unprognostic (1.72e-2)" "potential prognostic unfavorable (2.56e-4)" "unprognostic (1.21e-2)" "unprognostic (1.59e-1)" "unprognostic (1.90e-1)" "unprognostic (1.24e-1)" "unprognostic (1.39e-2)" "unprognostic (1.68e-1)" "unprognostic (3.58e-3)" "unprognostic (1.90e-1)" "unprognostic (4.79e-2)" "potential prognostic unfavorable (2.76e-4)" "unprognostic (9.22e-2)" "potential prognostic unfavorable (4.34e-4)" "unprognostic (1.46e-3)" "unprognostic (3.16e-1)" "unprognostic (1.24e-1)" "unprognostic (5.85e-2)" "unprognostic (7.51e-2)" "unprognostic (5.63e-3)" "unprognostic (1.91e-3)" "unprognostic (5.61e-2)" "unprognostic (4.16e-2)" "unprognostic (7.90e-3)" "unprognostic (3.50e-1)" "unprognostic (2.33e-1)" "unprognostic (1.96e-1)" "unprognostic (3.69e-2)" "unprognostic (2.27e-1)" MED16 "DRIP92, THRAP5, TRAP95" ENSG00000175221 "Mediator complex subunit 16" Q9Y2X0 19 867630-893218 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 57.3;Oocytes: 92.1;Platelets: 70.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030685, HPA046495" Uncertain Approved Nucleoli NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 83 Nucleoli "HPA030685: , HPA046495: " "unprognostic (2.73e-2)" "unprognostic (3.21e-1)" "unprognostic (1.48e-1)" "unprognostic (5.63e-2)" "unprognostic (1.89e-1)" "unprognostic (7.31e-2)" "unprognostic (4.61e-1)" "unprognostic (1.58e-1)" "unprognostic (2.83e-2)" "unprognostic (2.68e-2)" "unprognostic (5.40e-2)" "unprognostic (8.34e-2)" "unprognostic (5.04e-3)" "unprognostic (2.20e-2)" "unprognostic (5.41e-2)" "unprognostic (7.47e-2)" "unprognostic (4.21e-2)" "unprognostic (1.15e-1)" "unprognostic (1.29e-1)" "unprognostic (1.20e-1)" "unprognostic (3.18e-1)" "unprognostic (1.44e-3)" "unprognostic (9.59e-2)" "unprognostic (3.07e-2)" "unprognostic (1.93e-1)" "unprognostic (1.27e-1)" "unprognostic (5.06e-2)" "unprognostic (5.88e-3)" "unprognostic (3.39e-2)" "unprognostic (1.37e-1)" "unprognostic (1.46e-2)" MED17 "CRSP6, CRSP77, DRIP80, SRB4, TRAP80" ENSG00000042429 "Mediator complex subunit 17" Q9NVC6 11 93784227-93814963 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 22.5;Bergmann glia: 28.8;Brain excitatory neurons: 32.2;Brain inhibitory neurons: 30.3;Choroid plexus epithelial cells: 38.9;Ependymal cells: 22.2;Microglia: 33.9;Oligodendrocyte progenitor cells: 32.9;Oligodendrocytes: 31.5;Other brain neurons: 28.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046619 Approved "Nuclear speckles,Cytosol" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 49: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 22: Non-specific - Basic cellular functions" 165 "Nuclear speckles" Cytosol "HPA046619: " "unprognostic (4.69e-2)" "unprognostic (3.54e-2)" "unprognostic (3.87e-2)" "potential prognostic unfavorable (3.15e-4)" "unprognostic (5.80e-2)" "unprognostic (6.16e-2)" "unprognostic (1.81e-1)" "unprognostic (7.40e-2)" "unprognostic (9.47e-2)" "potential prognostic unfavorable (1.10e-4)" "unprognostic (1.73e-3)" "unprognostic (1.02e-1)" "unprognostic (3.09e-2)" "unprognostic (3.99e-1)" "unprognostic (1.51e-1)" "unprognostic (1.31e-2)" "unprognostic (2.73e-1)" "unprognostic (7.55e-2)" "unprognostic (1.50e-1)" "unprognostic (3.36e-1)" "unprognostic (3.53e-2)" "unprognostic (8.40e-3)" "unprognostic (2.43e-2)" "unprognostic (7.55e-3)" "unprognostic (1.67e-2)" "unprognostic (1.49e-2)" "unprognostic (4.57e-2)" "unprognostic (3.42e-1)" "unprognostic (1.91e-1)" "unprognostic (3.45e-1)" MED18 "FLJ20045, p28b, SRB5" ENSG00000130772 "Mediator complex subunit 18" Q9BUE0 1 28329002-28335965 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 1.6;Choroid plexus epithelial cells: 1.8;Distal convoluted tubule cells: 2.1;Gastric progenitor cells: 2.6;Loop of henle epithelial cells: 2.8;Microglia: 2.4;Oligodendrocytes: 1.6;Other brain neurons: 2.0;Papillary tip epithelial cells: 2.2;Podocytes: 2.8;Proximal tubule cells: 2.5;Renal collecting duct intercalated cells: 2.2;Renal collecting duct principal cells: 2.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027429 Uncertain Approved Nucleoplasm NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 24: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 37: Non-specific - mRNA processing" "Cluster 98: Neurons - Neurotransmission & signaling" 127 Nucleoplasm "HPA027429: " "unprognostic (2.75e-1)" "unprognostic (2.38e-3)" "unprognostic (4.28e-2)" "potential prognostic unfavorable (8.16e-4)" "potential prognostic favorable (4.99e-4)" "unprognostic (1.20e-1)" "unprognostic (2.14e-1)" "unprognostic (2.07e-1)" "unprognostic (2.46e-1)" "unprognostic (8.52e-3)" "potential prognostic favorable (5.63e-4)" "unprognostic (2.03e-2)" "potential prognostic favorable (1.40e-4)" "potential prognostic unfavorable (4.39e-5)" "unprognostic (1.17e-2)" "unprognostic (8.10e-2)" "unprognostic (1.22e-1)" "unprognostic (6.45e-2)" "unprognostic (4.17e-2)" "unprognostic (1.64e-1)" "unprognostic (9.49e-2)" "unprognostic (9.73e-2)" "unprognostic (5.54e-1)" "unprognostic (1.96e-1)" "unprognostic (1.89e-1)" "unprognostic (2.14e-1)" "unprognostic (1.28e-1)" "unprognostic (1.06e-3)" "unprognostic (2.73e-1)" "unprognostic (1.21e-1)" "potential prognostic favorable (5.63e-4)" MED19 LCMR1 ENSG00000156603 "Mediator complex subunit 19" A0JLT2 11 57703710-57712221 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 193.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039912, HPA040860" Uncertain Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 32: Basophils - Transcription" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 133 "Nuclear bodies" Nucleoplasm "HPA039912: , HPA040860: " "unprognostic (7.59e-2)" "unprognostic (3.96e-2)" "potential prognostic unfavorable (5.80e-4)" "unprognostic (1.40e-1)" "unprognostic (2.73e-1)" "unprognostic (2.76e-2)" "unprognostic (5.23e-2)" "unprognostic (7.43e-2)" "unprognostic (2.62e-2)" "unprognostic (6.66e-3)" "unprognostic (4.67e-2)" "unprognostic (2.27e-1)" "unprognostic (1.31e-1)" "validated prognostic unfavorable (1.34e-8)" "validated prognostic unfavorable (5.91e-4)" "unprognostic (1.44e-2)" "unprognostic (3.71e-2)" "unprognostic (1.01e-1)" "unprognostic (7.73e-2)" "potential prognostic favorable (8.98e-4)" "unprognostic (1.92e-3)" "unprognostic (3.51e-2)" "unprognostic (5.27e-2)" "unprognostic (1.60e-1)" "unprognostic (9.61e-2)" "unprognostic (1.61e-2)" "unprognostic (7.01e-2)" "unprognostic (1.32e-1)" "unprognostic (4.22e-1)" "unprognostic (2.42e-2)" "unprognostic (2.46e-1)" MED20 "DKFZp586D2223, PRO0213, SRB2, TRFP" ENSG00000124641 "Mediator complex subunit 20" Q9H944 6 41905354-41921139 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 3.2;Bergmann glia: 4.1;Brain excitatory neurons: 3.8;Brain inhibitory neurons: 3.2;Choroid plexus epithelial cells: 5.7;Distal convoluted tubule cells: 8.3;Ependymal cells: 4.6;Loop of henle epithelial cells: 5.7;Microglia: 3.0;Oligodendrocyte progenitor cells: 4.8;Oligodendrocytes: 3.4;Other brain neurons: 3.6;Papillary tip epithelial cells: 2.7;Podocytes: 2.8;Proximal tubule cells: 4.6;Renal collecting duct intercalated cells: 4.8;Renal collecting duct principal cells: 3.9;Renal connecting tubule cells: 3.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040717 Uncertain NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 28: Non-specific - Nuclear processes" "Cluster 102: Non-specific - Mixed function" 119 "HPA040717: " "unprognostic (9.34e-2)" "unprognostic (9.18e-2)" "unprognostic (2.33e-2)" "unprognostic (2.75e-2)" "unprognostic (4.76e-2)" "unprognostic (1.21e-2)" "unprognostic (4.99e-2)" "unprognostic (1.02e-1)" "unprognostic (2.63e-1)" "unprognostic (5.13e-3)" "potential prognostic favorable (7.16e-6)" "unprognostic (1.80e-3)" "unprognostic (4.99e-2)" "potential prognostic unfavorable (5.69e-4)" "unprognostic (1.73e-2)" "unprognostic (1.04e-1)" "unprognostic (8.49e-2)" "unprognostic (2.20e-1)" "unprognostic (1.71e-1)" "unprognostic (4.78e-2)" "unprognostic (6.41e-2)" "unprognostic (1.94e-2)" "unprognostic (7.69e-2)" "unprognostic (7.14e-2)" "unprognostic (2.83e-2)" "unprognostic (6.17e-2)" "potential prognostic unfavorable (1.60e-4)" "unprognostic (1.54e-2)" "unprognostic (2.15e-1)" "unprognostic (1.36e-2)" "unprognostic (9.91e-2)" MED21 "SRB7, SURB7" ENSG00000152944 "Mediator complex subunit 21" Q13503 12 27022546-27066343 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 240.0;Late primary spermatocytes: 307.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017177 Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 26: Keratinocytes - Keratinization" 160 Nucleoplasm "Nucleoli, Cytosol" "HPA017177: " "unprognostic (1.27e-1)" "unprognostic (6.86e-2)" "unprognostic (7.05e-3)" "unprognostic (1.72e-1)" "unprognostic (3.03e-1)" "unprognostic (4.28e-2)" "unprognostic (7.02e-2)" "unprognostic (2.33e-1)" "unprognostic (2.08e-1)" "unprognostic (7.87e-2)" "validated prognostic favorable (1.10e-7)" "validated prognostic favorable (1.62e-4)" "unprognostic (3.61e-1)" "unprognostic (3.40e-3)" "unprognostic (9.03e-2)" "unprognostic (4.66e-3)" "unprognostic (9.65e-2)" "unprognostic (2.15e-1)" "unprognostic (3.20e-3)" "unprognostic (6.42e-2)" "unprognostic (9.52e-2)" "potential prognostic unfavorable (3.75e-4)" "unprognostic (1.17e-3)" "unprognostic (4.77e-2)" "unprognostic (6.75e-3)" "unprognostic (1.05e-1)" "unprognostic (4.42e-2)" "unprognostic (6.28e-2)" "unprognostic (1.49e-1)" "unprognostic (3.21e-1)" "unprognostic (4.44e-1)" MED22 "Med24, SRB6, SURF5" ENSG00000148297 "Mediator complex subunit 22" Q15528 9 133338312-133348131 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 7.3;Bergmann glia: 6.0;Brain excitatory neurons: 4.9;Brain inhibitory neurons: 4.7;Choroid plexus epithelial cells: 5.7;Distal convoluted tubule cells: 5.7;Ependymal cells: 6.1;Loop of henle epithelial cells: 6.0;Microglia: 8.2;Oligodendrocyte progenitor cells: 5.5;Oligodendrocytes: 7.3;Other brain neurons: 5.5;Papillary tip epithelial cells: 4.6;Podocytes: 10.1;Proximal tubule cells: 7.4;Renal collecting duct intercalated cells: 4.9;Renal collecting duct principal cells: 6.0;Renal connecting tubule cells: 7.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020391, HPA063694" Uncertain Approved Nucleoplasm NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 102: Non-specific - Mixed function" 87 Nucleoplasm "HPA020391: , HPA063694: " "unprognostic (2.21e-1)" "unprognostic (4.79e-3)" "unprognostic (1.60e-3)" "unprognostic (1.80e-2)" "unprognostic (9.05e-3)" "unprognostic (8.56e-3)" "unprognostic (3.00e-1)" "potential prognostic favorable (2.81e-4)" "unprognostic (3.23e-2)" "unprognostic (2.17e-1)" "validated prognostic favorable (3.07e-6)" "validated prognostic favorable (5.91e-4)" "potential prognostic favorable (1.61e-4)" "potential prognostic unfavorable (7.79e-6)" "unprognostic (1.07e-2)" "unprognostic (3.41e-2)" "unprognostic (5.83e-2)" "unprognostic (1.40e-2)" "unprognostic (3.47e-2)" "unprognostic (9.92e-2)" "unprognostic (2.16e-1)" "unprognostic (1.05e-2)" "unprognostic (2.25e-1)" "unprognostic (3.71e-1)" "unprognostic (7.72e-2)" "unprognostic (1.90e-1)" "unprognostic (6.69e-2)" "unprognostic (2.23e-2)" "unprognostic (2.33e-1)" "unprognostic (4.44e-2)" "unprognostic (2.83e-2)" MED23 "CRSP130, CRSP3, DRIP130, MRT18, Sur2" ENSG00000112282 "Mediator complex subunit 23" Q9ULK4 6 131573966-131628242 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070341 Approved Nucleoplasm,Vesicles NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" 94 Nucleoplasm Vesicles "HPA070341: " "unprognostic (4.52e-1)" "unprognostic (2.54e-3)" "unprognostic (7.72e-2)" "unprognostic (3.69e-3)" "unprognostic (6.03e-1)" "unprognostic (7.92e-3)" "unprognostic (8.15e-3)" "unprognostic (2.22e-3)" "unprognostic (7.43e-2)" "unprognostic (1.81e-3)" "potential prognostic favorable (1.15e-5)" "unprognostic (6.19e-3)" "unprognostic (1.56e-1)" "unprognostic (4.79e-2)" "unprognostic (2.60e-2)" "unprognostic (3.83e-1)" "unprognostic (1.06e-1)" "unprognostic (4.95e-2)" "unprognostic (6.55e-3)" "unprognostic (1.17e-3)" "unprognostic (1.88e-1)" "unprognostic (2.68e-1)" "unprognostic (6.35e-2)" "unprognostic (2.56e-1)" "unprognostic (5.44e-3)" "unprognostic (2.42e-1)" "unprognostic (3.56e-1)" "unprognostic (6.18e-2)" "unprognostic (1.67e-1)" "unprognostic (8.32e-2)" "unprognostic (1.09e-1)" MED24 "CRSP100, CRSP4, DRIP100, KIAA0130, MED5, THRAP4, TRAP100" ENSG00000008838 "Mediator complex subunit 24" O75448 17 40019097-40061215 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 217.5;Endometrial secretory cells: 118.3;Salivary duct cells: 274.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 24: Non-specific - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 86 "unprognostic (2.68e-1)" "unprognostic (1.54e-1)" "unprognostic (2.78e-2)" "unprognostic (1.66e-1)" "unprognostic (5.54e-2)" "unprognostic (6.41e-2)" "unprognostic (2.13e-1)" "unprognostic (1.00e-3)" "unprognostic (3.86e-2)" "unprognostic (6.35e-2)" "potential prognostic favorable (6.46e-5)" "unprognostic (3.37e-2)" "unprognostic (3.95e-2)" "unprognostic (2.01e-3)" "potential prognostic unfavorable (6.75e-4)" "unprognostic (9.35e-2)" "unprognostic (5.95e-2)" "unprognostic (4.00e-1)" "unprognostic (4.58e-2)" "unprognostic (9.52e-2)" "unprognostic (1.23e-2)" "unprognostic (5.76e-2)" "potential prognostic unfavorable (7.26e-4)" "unprognostic (2.78e-1)" "potential prognostic favorable (1.49e-4)" "unprognostic (4.72e-2)" "unprognostic (4.56e-1)" "unprognostic (5.57e-2)" "unprognostic (1.83e-1)" "unprognostic (2.10e-1)" "unprognostic (3.14e-1)" MED25 "ACID1, ARC92, DKFZp434K0512, TCBAP0758" ENSG00000104973 "Mediator complex subunit 25" Q71SY5 19 49818282-49840383 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Charcot-Marie-Tooth disease, Disease variant, Intellectual disability, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 184.5;Sertoli cells: 155.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 13.8" "Lineage enriched" "Detected in many" 4 "granulocytes: 13.8" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068802 Approved Supported Nucleoplasm NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 67: Testis - Mixed function" "Cluster 17: Choroid plexus - Cilium" "Cluster 4: Non-specific - Transcription" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 85 Nucleoplasm "HPA068802: " "unprognostic (1.33e-2)" "unprognostic (1.83e-1)" "unprognostic (1.59e-1)" "unprognostic (3.17e-2)" "unprognostic (2.12e-1)" "unprognostic (5.05e-1)" "unprognostic (2.57e-1)" "unprognostic (5.25e-2)" "unprognostic (1.73e-2)" "unprognostic (1.74e-1)" "unprognostic (2.22e-2)" "unprognostic (2.24e-1)" "unprognostic (1.74e-1)" "potential prognostic unfavorable (2.96e-5)" "unprognostic (3.11e-1)" "unprognostic (2.51e-1)" "unprognostic (1.86e-1)" "unprognostic (1.50e-1)" "unprognostic (9.05e-2)" "unprognostic (1.93e-1)" "unprognostic (4.75e-2)" "unprognostic (5.75e-2)" "unprognostic (8.18e-2)" "unprognostic (3.98e-3)" "unprognostic (2.95e-1)" "unprognostic (5.87e-2)" "unprognostic (1.55e-1)" "unprognostic (2.03e-1)" "unprognostic (4.65e-2)" "unprognostic (5.28e-2)" "unprognostic (6.02e-2)" MED26 "CRSP7, CRSP70" ENSG00000105085 "Mediator complex subunit 26" O95402 19 16574907-16629062 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 34.0" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in all" 8 "Uterine Corpus Endometrial Carcinoma (TCGA): 92.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036798, HPA057997, HPA071835" Enhanced Approved "Nucleoplasm,Mitotic chromosome" Yes No "Cluster 32: Basophils - Transcription" "Cluster 39: Testis - Nuclear processes" "Cluster 25: Non-specific - Transcription" "Cluster 23: Non-specific - Transcription" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 101 Nucleoplasm "Mitotic chromosome" "HPA036798: , HPA057997: , HPA071835: " "unprognostic (6.86e-3)" "unprognostic (7.81e-2)" "unprognostic (7.26e-2)" "unprognostic (1.09e-1)" "unprognostic (1.10e-1)" "unprognostic (1.85e-1)" "unprognostic (1.49e-1)" "unprognostic (2.41e-1)" "unprognostic (6.50e-3)" "unprognostic (2.37e-2)" "unprognostic (6.85e-3)" "unprognostic (9.59e-2)" "unprognostic (1.07e-1)" "unprognostic (3.95e-1)" "unprognostic (6.81e-2)" "unprognostic (5.36e-3)" "unprognostic (5.98e-2)" "unprognostic (2.77e-1)" "unprognostic (4.60e-2)" "unprognostic (9.94e-2)" "unprognostic (2.70e-1)" "unprognostic (1.08e-3)" "unprognostic (7.02e-2)" "unprognostic (2.67e-2)" "unprognostic (3.27e-2)" "potential prognostic favorable (8.56e-4)" "unprognostic (1.51e-1)" "unprognostic (1.81e-2)" "unprognostic (4.59e-2)" "unprognostic (2.79e-2)" "unprognostic (2.75e-1)" MED27 "CRSP34, CRSP8, MED3, TRAP37" ENSG00000160563 "Mediator complex subunit 27" Q6P2C8 9 131852928-132079867 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cataract, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Podocytes: 318.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007002 Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 64: Non-specific - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Transcription" 129 "Nucleoplasm, Nucleoli" Cytosol "HPA007002: " "unprognostic (1.23e-3)" "unprognostic (7.25e-3)" "potential prognostic unfavorable (2.11e-4)" "potential prognostic favorable (2.63e-6)" "unprognostic (6.20e-2)" "potential prognostic unfavorable (5.09e-4)" "unprognostic (1.85e-1)" "unprognostic (1.72e-2)" "unprognostic (1.49e-2)" "unprognostic (8.50e-2)" "unprognostic (2.08e-3)" "unprognostic (8.64e-2)" "unprognostic (3.70e-1)" "unprognostic (8.60e-3)" "unprognostic (2.69e-2)" "unprognostic (8.52e-2)" "unprognostic (6.54e-2)" "unprognostic (2.01e-1)" "unprognostic (6.18e-2)" "unprognostic (6.40e-2)" "unprognostic (1.64e-1)" "unprognostic (1.08e-2)" "unprognostic (9.35e-2)" "unprognostic (1.40e-1)" "unprognostic (3.68e-1)" "unprognostic (6.98e-2)" "unprognostic (8.80e-2)" "unprognostic (3.85e-1)" "unprognostic (2.74e-2)" "unprognostic (1.27e-1)" "unprognostic (2.01e-1)" MED28 "DKFZP434N185, EG1, magicin" ENSG00000118579 "Mediator complex subunit 28" Q9H204 4 17614641-17634105 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Actin-binding, Activator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 203.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035900, HPA035901" Uncertain Supported Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 15: Non-specific - Protein processing" 168 Nucleoplasm "HPA035900: , HPA035901: " "potential prognostic favorable (8.68e-4)" "unprognostic (1.53e-1)" "unprognostic (8.30e-2)" "unprognostic (1.60e-2)" "unprognostic (3.56e-1)" "unprognostic (2.77e-1)" "unprognostic (5.51e-2)" "unprognostic (1.72e-3)" "unprognostic (2.04e-1)" "unprognostic (3.95e-2)" "unprognostic (5.50e-3)" "potential prognostic favorable (4.21e-5)" "unprognostic (2.28e-1)" "unprognostic (1.01e-2)" "unprognostic (6.40e-3)" "unprognostic (3.38e-1)" "unprognostic (7.71e-3)" "unprognostic (9.10e-2)" "unprognostic (3.42e-2)" "unprognostic (1.46e-1)" "unprognostic (1.92e-1)" "unprognostic (1.57e-2)" "unprognostic (5.35e-2)" "unprognostic (2.93e-2)" "unprognostic (1.53e-1)" "unprognostic (7.15e-2)" "unprognostic (9.38e-3)" "unprognostic (1.99e-1)" "unprognostic (4.57e-1)" "unprognostic (1.17e-1)" "unprognostic (7.18e-2)" MED29 "DKFZp434H247, IXL, MED2" ENSG00000063322 "Mediator complex subunit 29" Q9NX70 19 39391303-39400641 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" HPA055956 Supported Nucleoplasm NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 78: Brain - Neuronal signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 65: Non-specific - Cell growth & division" 154 Nucleoplasm "HPA055956: " "unprognostic (5.44e-2)" "unprognostic (2.10e-1)" "unprognostic (6.46e-2)" "unprognostic (1.13e-1)" "unprognostic (3.15e-1)" "unprognostic (1.01e-1)" "unprognostic (8.05e-2)" "unprognostic (8.17e-3)" "unprognostic (1.57e-1)" "unprognostic (3.33e-1)" "potential prognostic favorable (8.38e-7)" "unprognostic (7.16e-3)" "unprognostic (3.30e-2)" "unprognostic (1.51e-1)" "unprognostic (2.10e-1)" "unprognostic (3.53e-1)" "unprognostic (2.26e-1)" "unprognostic (4.22e-2)" "unprognostic (2.57e-1)" "unprognostic (5.22e-2)" "unprognostic (4.42e-2)" "unprognostic (1.78e-1)" "unprognostic (1.88e-2)" "unprognostic (1.70e-1)" "unprognostic (1.28e-2)" "unprognostic (2.16e-1)" "unprognostic (4.72e-3)" "unprognostic (1.69e-2)" "unprognostic (3.10e-1)" "unprognostic (4.13e-1)" "unprognostic (5.84e-2)" MED30 "THRAP6, TRAP25" ENSG00000164758 "Mediator complex subunit 30" Q96HR3 8 117520713-117540262 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 130.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045767 Approved Nucleoplasm NA NA "Cluster 32: Basophils - Transcription" "Cluster 15: Bone marrow - Innate immune response" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 26: Keratinocytes - Keratinization" 92 Nucleoplasm "HPA045767: " "unprognostic (2.36e-1)" "unprognostic (6.43e-2)" "unprognostic (1.91e-1)" "potential prognostic unfavorable (7.50e-4)" "unprognostic (3.52e-2)" "unprognostic (1.66e-1)" "unprognostic (1.97e-1)" "unprognostic (1.53e-3)" "unprognostic (2.07e-2)" "unprognostic (6.38e-3)" "potential prognostic favorable (1.63e-4)" "unprognostic (1.22e-1)" "potential prognostic unfavorable (5.62e-4)" "unprognostic (5.98e-3)" "potential prognostic unfavorable (7.26e-4)" "unprognostic (6.97e-2)" "unprognostic (1.26e-2)" "unprognostic (1.03e-1)" "unprognostic (5.56e-2)" "unprognostic (1.07e-2)" "unprognostic (6.49e-2)" "potential prognostic unfavorable (3.61e-4)" "unprognostic (1.33e-1)" "unprognostic (9.23e-2)" "unprognostic (1.82e-1)" "unprognostic (2.01e-2)" "unprognostic (2.23e-1)" "unprognostic (2.95e-2)" "unprognostic (4.87e-1)" "unprognostic (3.10e-1)" "unprognostic (1.20e-1)" MED31 "CGI-125, Soh1" ENSG00000108590 "Mediator complex subunit 31" Q9Y3C7 17 6643311-6651634 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 240.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035947 Uncertain Approved Nucleoplasm No No "Cluster 35: Neutrophils - Protein binding" "Cluster 2: Non-specific - Mixed function" "Cluster 14: Neurons - Synaptic function" "Cluster 42: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 135 Nucleoplasm "HPA035947: " "unprognostic (1.98e-1)" "unprognostic (6.28e-2)" "unprognostic (1.10e-3)" "unprognostic (1.03e-1)" "unprognostic (4.73e-2)" "unprognostic (1.27e-1)" "unprognostic (1.19e-1)" "unprognostic (1.89e-1)" "unprognostic (6.10e-2)" "unprognostic (7.11e-3)" "unprognostic (4.70e-2)" "unprognostic (2.30e-2)" "unprognostic (3.81e-2)" "unprognostic (1.09e-2)" "unprognostic (3.94e-2)" "unprognostic (1.17e-2)" "unprognostic (1.83e-1)" "unprognostic (5.91e-2)" "unprognostic (1.39e-1)" "unprognostic (1.39e-2)" "unprognostic (7.61e-2)" "unprognostic (2.51e-2)" "potential prognostic unfavorable (1.16e-4)" "unprognostic (2.47e-2)" "unprognostic (8.22e-2)" "unprognostic (2.58e-1)" "unprognostic (5.09e-2)" "unprognostic (1.20e-1)" "unprognostic (4.03e-1)" "unprognostic (2.97e-2)" "unprognostic (1.19e-2)" MED4 "DRIP36, HSPC126, TRAP36, VDRIP" ENSG00000136146 "Mediator complex subunit 4" Q9NPJ6 13 48053323-48095131 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006232 Approved Supported Nucleoplasm NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 19: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 215 Nucleoplasm "HPA006232: " "unprognostic (3.98e-3)" "unprognostic (8.69e-2)" "potential prognostic unfavorable (7.10e-4)" "unprognostic (2.33e-2)" "unprognostic (3.21e-1)" "unprognostic (6.23e-2)" "unprognostic (2.13e-1)" "unprognostic (2.76e-1)" "unprognostic (2.30e-3)" "unprognostic (2.49e-1)" "potential prognostic favorable (1.56e-8)" "unprognostic (1.78e-3)" "unprognostic (4.86e-2)" "unprognostic (1.10e-3)" "potential prognostic unfavorable (2.86e-4)" "unprognostic (2.73e-1)" "unprognostic (4.82e-2)" "unprognostic (7.28e-2)" "unprognostic (2.84e-1)" "unprognostic (5.93e-3)" "unprognostic (1.72e-1)" "unprognostic (3.26e-2)" "unprognostic (1.27e-2)" "unprognostic (1.75e-1)" "unprognostic (1.58e-1)" "unprognostic (4.60e-2)" "unprognostic (3.00e-3)" "unprognostic (3.51e-2)" "unprognostic (1.01e-1)" "unprognostic (9.29e-2)" "unprognostic (3.31e-1)" MED6 NY-REN-28 ENSG00000133997 "Mediator complex subunit 6" O75586 14 70581257-70600690 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 122.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030764, HPA069039" Approved Enhanced Nucleoplasm NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 7: Non-specific - Transcription" 119 Nucleoplasm "HPA030764: , HPA069039: " "unprognostic (1.28e-1)" "unprognostic (1.75e-1)" "unprognostic (3.72e-2)" "unprognostic (1.84e-1)" "unprognostic (1.40e-1)" "unprognostic (3.11e-2)" "unprognostic (9.71e-2)" "unprognostic (4.32e-3)" "unprognostic (1.99e-2)" "unprognostic (1.37e-3)" "potential prognostic favorable (2.77e-4)" "unprognostic (2.51e-2)" "unprognostic (2.31e-1)" "potential prognostic unfavorable (2.20e-5)" "unprognostic (9.22e-3)" "potential prognostic unfavorable (7.97e-4)" "unprognostic (3.55e-3)" "unprognostic (3.78e-2)" "unprognostic (2.79e-1)" "unprognostic (1.67e-1)" "unprognostic (6.43e-2)" "unprognostic (1.54e-1)" "potential prognostic unfavorable (2.51e-5)" "unprognostic (9.94e-2)" "unprognostic (2.15e-1)" "unprognostic (1.38e-2)" "unprognostic (2.37e-3)" "unprognostic (1.28e-1)" "unprognostic (8.95e-2)" "unprognostic (2.67e-1)" "unprognostic (1.85e-1)" MED7 "CRSP33, CRSP9" ENSG00000155868 "Mediator complex subunit 7" O43513 5 157137424-157159019 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 47.9;Late primary spermatocytes: 16.1;Late spermatids: 30.5;Tuft cells: 11.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067181 Supported "Nuclear bodies" No No "Cluster 45: Eosinophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" 100 "Nuclear bodies" "HPA067181: " "unprognostic (6.65e-3)" "unprognostic (2.31e-1)" "unprognostic (1.79e-1)" "unprognostic (9.22e-2)" "unprognostic (8.46e-2)" "unprognostic (6.00e-2)" "potential prognostic unfavorable (1.69e-6)" "unprognostic (4.02e-2)" "unprognostic (1.07e-2)" "unprognostic (2.17e-3)" "potential prognostic favorable (6.79e-10)" "unprognostic (4.09e-3)" "potential prognostic favorable (1.33e-4)" "potential prognostic unfavorable (1.04e-5)" "unprognostic (2.73e-1)" "unprognostic (2.00e-2)" "unprognostic (2.12e-1)" "unprognostic (1.28e-1)" "unprognostic (3.04e-1)" "unprognostic (2.54e-2)" "unprognostic (1.82e-2)" "unprognostic (3.70e-1)" "unprognostic (5.74e-3)" "unprognostic (5.91e-2)" "potential prognostic favorable (4.09e-4)" "unprognostic (6.72e-2)" "unprognostic (5.84e-2)" "unprognostic (1.99e-1)" "unprognostic (1.75e-1)" "unprognostic (8.49e-2)" "unprognostic (4.75e-2)" MED8 "ARC32, MGC17544, MGC19641" ENSG00000159479 "Mediator complex subunit 8" Q96G25 1 43383917-43389808 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 233.2;Esophageal suprabasal cells: 135.7;Oocytes: 142.8;Syncytiotrophoblasts: 109.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028377, HPA028438" Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 85: Squamous epithelial cells - Keratinization" 94 Nucleoplasm "Golgi apparatus" "HPA028377: , HPA028438: " "unprognostic (3.23e-1)" "unprognostic (3.76e-2)" "unprognostic (6.60e-2)" "unprognostic (2.65e-1)" "unprognostic (3.98e-2)" "unprognostic (1.11e-1)" "unprognostic (1.72e-2)" "unprognostic (2.08e-1)" "unprognostic (1.08e-1)" "unprognostic (3.48e-3)" "unprognostic (2.48e-3)" "unprognostic (4.72e-2)" "unprognostic (1.42e-1)" "validated prognostic unfavorable (1.44e-8)" "validated prognostic unfavorable (9.45e-5)" "unprognostic (1.89e-1)" "unprognostic (1.48e-2)" "unprognostic (4.72e-2)" "unprognostic (2.02e-1)" "unprognostic (3.67e-1)" "unprognostic (1.75e-1)" "unprognostic (1.44e-2)" "unprognostic (1.84e-1)" "unprognostic (7.45e-3)" "unprognostic (8.96e-2)" "unprognostic (2.46e-1)" "unprognostic (4.09e-2)" "unprognostic (1.52e-1)" "unprognostic (1.51e-1)" "unprognostic (9.65e-3)" "unprognostic (8.21e-2)" MED9 "FLJ10193, MED25" ENSG00000141026 "Mediator complex subunit 9" Q9NWA0 17 17476994-17493221 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Minor Salivary Gland - Minor salivary glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056415 Uncertain Approved Nucleoplasm,Midbody Yes No "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 42: Non-specific - Unknown function" "Cluster 55: Myocytes - Oxidative muscle function" 140 Nucleoplasm Midbody "HPA056415: " "unprognostic (1.14e-2)" "unprognostic (3.46e-1)" "unprognostic (1.67e-1)" "unprognostic (2.67e-1)" "unprognostic (3.14e-1)" "unprognostic (1.18e-1)" "unprognostic (3.79e-1)" "unprognostic (5.58e-3)" "unprognostic (2.36e-1)" "unprognostic (2.47e-1)" "validated prognostic favorable (2.82e-6)" "validated prognostic favorable (3.59e-4)" "unprognostic (1.52e-2)" "unprognostic (2.07e-1)" "unprognostic (1.54e-1)" "unprognostic (1.75e-1)" "unprognostic (1.28e-1)" "unprognostic (1.63e-1)" "unprognostic (5.61e-1)" "unprognostic (1.40e-1)" "unprognostic (1.57e-1)" "potential prognostic favorable (2.14e-5)" "unprognostic (9.68e-2)" "unprognostic (6.55e-3)" "unprognostic (2.79e-2)" "unprognostic (1.42e-1)" "unprognostic (2.05e-1)" "unprognostic (7.74e-2)" "unprognostic (2.14e-1)" "unprognostic (1.40e-1)" "unprognostic (2.32e-1)" MEDAG "AWMS3, C13orf33, FLJ14834, MEDA-4" ENSG00000102802 "Mesenteric estrogen dependent adipogenesis" Q5VYS4 13 30906271-30925572 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 160.7;blood vessel: 138.5" "Cell type enhanced" "Detected in some" "Decidual stromal cells: 251.3;Endometrial stromal cells: 75.2;Epicardial cells: 56.9;Fibro-adipogenic progenitors: 85.0;Fibroblasts: 227.4;Lymphatic endothelial cells: 54.8;Mesothelial cells: 169.3" "Group enriched" "Detected in some" 29 "endothelial cell: 35.9;fibroblast: 10.4;vascular associated smooth muscle cell: 11.0" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "cerebral cortex: 2.6;choroid plexus: 8.5;hypothalamus: 3.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Sarcoma: 15.9;testis cancer: 5.5" "Testis - Leydig cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 36: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 4 "unprognostic (2.47e-1)" "unprognostic (1.31e-1)" "unprognostic (1.83e-2)" "unprognostic (5.31e-2)" "unprognostic (1.57e-1)" "unprognostic (3.57e-3)" "unprognostic (1.91e-3)" "unprognostic (5.61e-2)" "unprognostic (2.00e-1)" "unprognostic (3.68e-1)" "unprognostic (2.01e-3)" "unprognostic (1.42e-1)" "unprognostic (4.32e-2)" "unprognostic (1.44e-2)" "unprognostic (3.07e-3)" "unprognostic (3.76e-2)" "unprognostic (3.06e-2)" "unprognostic (7.01e-2)" "unprognostic (1.78e-1)" "unprognostic (2.15e-1)" "unprognostic (2.54e-1)" "unprognostic (1.57e-1)" "unprognostic (7.27e-2)" "unprognostic (2.44e-1)" "unprognostic (1.07e-3)" "unprognostic (2.38e-1)" "unprognostic (6.93e-3)" "unprognostic (1.71e-1)" MEF2A "RSRFC4, RSRFC9" ENSG00000068305 "Myocyte enhancer factor 2A" Q02078 15 99565417-99716488 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglia: 3037.3;Neutrophils: 1663.6" "Group enriched" "Detected in all" 4 "central nervous system macrophage: 3820.0;endothelial cell: 1120.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004499, HPA046597, HPA056563" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 6: Leukemia - Signal transduction" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 19 Nucleoplasm Cytosol "CAB004499: , HPA046597: , HPA056563: " "unprognostic (5.40e-2)" "unprognostic (2.89e-1)" "unprognostic (4.67e-3)" "unprognostic (2.23e-1)" "unprognostic (1.84e-1)" "unprognostic (2.87e-2)" "unprognostic (2.83e-1)" "unprognostic (1.76e-1)" "unprognostic (3.93e-1)" "unprognostic (7.81e-2)" "potential prognostic favorable (3.69e-6)" "unprognostic (1.94e-3)" "unprognostic (3.82e-3)" "unprognostic (2.23e-1)" "unprognostic (2.17e-1)" "unprognostic (8.08e-2)" "unprognostic (1.86e-2)" "unprognostic (3.27e-2)" "unprognostic (1.94e-1)" "unprognostic (2.43e-2)" "unprognostic (1.08e-3)" "unprognostic (1.68e-2)" "unprognostic (1.64e-2)" "unprognostic (4.03e-1)" "unprognostic (2.26e-1)" "unprognostic (5.91e-3)" "unprognostic (9.21e-3)" "unprognostic (2.53e-3)" "unprognostic (2.28e-1)" "unprognostic (2.51e-1)" "unprognostic (7.94e-3)" MEF2B RSRFR2 ENSG00000213999 "Myocyte enhancer factor 2B" Q02080 19 19145567-19192131 "Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "lymphoid tissue: 36.7" "Cell type enhanced" "Detected in some" "Astrocytes: 14.9;Bergmann glia: 12.5;Choroid plexus epithelial cells: 36.4;Ependymal cells: 25.3;Microglia: 14.8;Oligodendrocyte progenitor cells: 8.8;Oligodendrocytes: 13.5" "Cell type enhanced" "Detected in many" "vascular associated smooth muscle cell: 35.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "lymphoma: 251.1" "Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA004734 Supported Approved "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 18: Lymphoid tissue - Immune response" "Cluster 11: White matter - Signal transduction" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 67: Plasma cells - Plasma cell differentiation" 5 "Nucleoplasm, Cytosol" "Cell Junctions" "HPA004734: " "unprognostic (3.11e-2)" "unprognostic (4.37e-3)" "unprognostic (2.65e-1)" "potential prognostic favorable (1.78e-4)" "unprognostic (1.29e-2)" "unprognostic (3.14e-2)" "unprognostic (9.37e-3)" "unprognostic (1.78e-3)" "unprognostic (2.02e-1)" "potential prognostic unfavorable (4.90e-7)" "unprognostic (9.46e-2)" "unprognostic (2.16e-1)" "unprognostic (1.15e-1)" "unprognostic (3.79e-2)" "unprognostic (3.68e-2)" "unprognostic (5.17e-2)" "unprognostic (4.11e-2)" "unprognostic (3.91e-2)" "unprognostic (2.18e-2)" "unprognostic (4.50e-2)" "unprognostic (6.27e-3)" "unprognostic (1.33e-2)" "unprognostic (1.05e-2)" "unprognostic (2.36e-1)" "unprognostic (2.36e-2)" "unprognostic (1.25e-1)" "unprognostic (1.52e-1)" "unprognostic (7.50e-2)" "unprognostic (1.05e-1)" "unprognostic (3.05e-2)" MEF2C ENSG00000081189 "Myocyte enhancer factor 2C" Q06413 5 88717117-88904257 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 522.1;tongue: 231.4" "Cell type enhanced" "Detected in many" "B-cells: 1114.2;Hofbauer cells: 669.1;Macrophages: 688.0;Megakaryocyte progenitors: 706.9;Microglia: 2881.3;Myonuclei: 3220.5;Plasma cells: 712.5;Thymic myoid cells: 727.4;Vascular endothelial cells: 666.6" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 3465.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 72.1;intermediate monocyte: 82.7;memory B-cell: 142.1;myeloid DC: 95.3;naive B-cell: 188.5;non-classical monocyte: 71.9;plasmacytoid DC: 100.4" "Group enriched" "Detected in many" 5 "B-cells: 188.5;dendritic cells: 100.4;monocytes: 82.7" "Cancer enhanced" "Detected in many" "Leukemia: 105.1;lymphoma: 81.8;Myeloma: 177.5" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells, Pancreas - Endothelial cells, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "amygdala: 112.9;cerebral cortex: 397.9;hippocampal formation: 346.6;olfactory bulb: 109.7" "HPA005533, CAB068196, CAB068197" Enhanced Supported Nucleoplasm,Vesicles NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 53: Neurons - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 16 "Nucleoplasm, Vesicles" "CAB068196: , CAB068197: , HPA005533: " "unprognostic (2.10e-2)" "unprognostic (1.25e-1)" "unprognostic (2.26e-1)" "unprognostic (1.24e-1)" "unprognostic (5.57e-2)" "unprognostic (1.74e-1)" "unprognostic (3.08e-1)" "unprognostic (6.50e-2)" "unprognostic (1.13e-1)" "unprognostic (7.10e-2)" "validated prognostic favorable (2.47e-5)" "validated prognostic favorable (1.26e-4)" "unprognostic (1.17e-1)" "unprognostic (5.04e-2)" "unprognostic (8.07e-2)" "unprognostic (3.65e-3)" "unprognostic (1.27e-2)" "unprognostic (7.72e-2)" "unprognostic (5.34e-2)" "unprognostic (2.17e-1)" "unprognostic (1.96e-2)" "unprognostic (1.05e-1)" "unprognostic (1.59e-1)" "unprognostic (1.34e-1)" "unprognostic (6.10e-2)" "unprognostic (7.49e-2)" "unprognostic (6.77e-2)" "unprognostic (1.71e-2)" "unprognostic (1.11e-1)" "unprognostic (1.27e-1)" "unprognostic (2.59e-1)" MEF2D ENSG00000116604 "Myocyte enhancer factor 2D" Q14814 1 156463727-156500779 "Predicted intracellular proteins, Transcription factors" "Apoptosis, Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 157.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 217.4;Neutrophils: 258.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004807, HPA007114" Enhanced Enhanced Nucleoplasm,Vesicles NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 13 Nucleoplasm Vesicles "HPA004807: , HPA007114: " "unprognostic (3.35e-3)" "unprognostic (7.70e-2)" "unprognostic (2.23e-2)" "unprognostic (1.70e-2)" "unprognostic (1.59e-1)" "unprognostic (2.08e-2)" "unprognostic (4.36e-1)" "unprognostic (1.04e-1)" "unprognostic (4.45e-1)" "unprognostic (2.03e-2)" "potential prognostic favorable (2.39e-6)" "unprognostic (2.09e-3)" "unprognostic (1.67e-1)" "unprognostic (7.16e-2)" "unprognostic (1.22e-2)" "unprognostic (1.21e-1)" "unprognostic (4.44e-2)" "unprognostic (7.01e-2)" "unprognostic (1.07e-1)" "unprognostic (7.87e-2)" "potential prognostic unfavorable (5.94e-4)" "unprognostic (2.46e-2)" "unprognostic (1.31e-1)" "unprognostic (1.15e-1)" "unprognostic (2.82e-2)" "unprognostic (2.18e-2)" "unprognostic (7.05e-2)" "unprognostic (3.15e-1)" "unprognostic (2.55e-1)" "unprognostic (1.19e-3)" "unprognostic (6.47e-2)" MEFV "FMF, MEF, TRIM20" ENSG00000103313 "MEFV innate immuity regulator, pyrin" O15553 16 3242027-3256633 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Immunity, Inflammatory response, Innate immunity" Actin-binding "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.1;lung: 3.9;lymphoid tissue: 8.5" "Cell type enriched" "Detected in some" 4 "Neutrophils: 286.6" "Cell type enriched" "Detected in some" 4 "leukocyte: 8.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 7.6" "Group enriched" "Detected in many" 4 "granulocytes: 7.6;monocytes: 5.6" "Cancer enhanced" "Detected in single" "Leukemia: 1.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Neutrophils, Adrenal gland - Macrophages, Breast - Macrophages, Heart muscle - Neutrophils, Liver - Neutrophils, Skin - Macrophages, Spleen - Neutrophils_2, Thyroid gland - Neutrophils" "Not detected" "Not detected" "HPA066867, HPA067626" Enhanced "Plasma membrane" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 7 "Plasma membrane" "HPA066867: , HPA067626: " "unprognostic (8.58e-2)" "unprognostic (1.78e-1)" "unprognostic (7.84e-2)" "unprognostic (1.07e-1)" "unprognostic (2.29e-1)" "unprognostic (2.02e-2)" "unprognostic (1.22e-1)" "unprognostic (4.09e-2)" "unprognostic (2.08e-1)" MEGF10 "KIAA1780, SR-F3" ENSG00000145794 "Multiple EGF like domains 10" Q96KG7 5 127290796-127465737 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Myogenesis, Phagocytosis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 12.2;retina: 7.4" "Cell type enhanced" "Detected in many" "Astrocytes: 300.8;Ependymal cells: 70.4;Müller glia: 186.0;Myosatellite cells: 365.0;Oligodendrocyte progenitor cells: 108.9;Oligodendrocytes: 455.9;Other brain neurons: 109.2;Pituicytes/FSCs: 127.5;Pituitary stem cells: 80.8" "Cell type enhanced" "Detected in all" "astrocyte: 343.9;cerebellar inhibitory: 510.3;oligodendrocyte: 637.4" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 6.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Sarcoma: 10.0;skin cancer: 6.9" "Adrenal gland - Adrenal cortex cells, Breast - Breast myoepithelial cells, Colon - Enteric glia cells, Liver - Hepatocytes, Minor Salivary Gland - Smooth muscle cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011401 Supported "Plasma membrane" "Intracellular and membrane" "Cell adhesion" NA NA 8100000 "Cluster 3: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 80: Oligodendrocytes - Myelination" 1 "Plasma membrane" "HPA011401: " "unprognostic (6.64e-2)" "unprognostic (1.87e-1)" "unprognostic (5.66e-2)" "potential prognostic unfavorable (6.09e-4)" "unprognostic (6.15e-2)" "unprognostic (1.35e-3)" "unprognostic (4.93e-2)" "unprognostic (1.12e-1)" MEGF11 "DKFZp434L121, KIAA1781" ENSG00000157890 "Multiple EGF like domains 11" A6BM72 15 65895079-66253756 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 23.8;fallopian tube: 6.1;kidney: 7.0;retina: 11.3" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 134.4;Early spermatids: 179.5;Late primary spermatocytes: 69.6;Late spermatids: 274.0;Oligodendrocyte progenitor cells: 1037.4;Oligodendrocytes: 100.7;Other brain neurons: 96.8;Renal connecting tubule cells: 94.3;Retinal horizontal cells: 106.2" "Group enriched" "Detected in all" 4 "committed oligodendrocyte precursor: 462.0;oligodendrocyte precursor cell: 1273.9;upper rhombic lip: 336.4" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 7.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lymphoma: 2.1" "Pituitary gland - Corticotropes, Stomach - Gastric enteroendocrine cells, Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in all" 4 "cerebellum: 35.0" "Region enriched" "Detected in all" 7 "cerebellum: 43.9" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 35: Non-specific - DNA binding" "Cluster 6: Leukemia - Signal transduction" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 1 "unprognostic (3.51e-1)" "unprognostic (3.55e-2)" "potential prognostic favorable (8.42e-4)" "unprognostic (3.18e-1)" "unprognostic (1.37e-1)" "unprognostic (3.03e-1)" "unprognostic (1.24e-1)" "unprognostic (1.21e-1)" "unprognostic (1.70e-1)" "unprognostic (1.04e-1)" MEGF6 EGFL3 ENSG00000162591 "Multiple EGF like domains 6" O75095 1 3487951-3611508 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 85.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 40.2;Basal prostatic cells: 50.2;Epicardial cells: 100.1;Hepatic stellate cells: 71.0;Lymphatic endothelial cells: 42.8;Müller glia: 38.9;Salivary myoepithelial cells: 34.9" "Cell type enriched" "Detected in many" 4 "endothelial cell: 50.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 1.9" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Liver - Hepatic stellate cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate basal glandular cells, Testis - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA052129 Uncertain Approved "Microtubules,Cytokinetic bridge" "Secreted to blood" "No annotated function" Yes No 250000 "Cluster 22: Eosinophils - Transcription" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 19: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 3 Microtubules "Cytokinetic bridge" "HPA052129: " "potential prognostic favorable (4.63e-4)" "unprognostic (1.69e-2)" "unprognostic (1.51e-1)" "unprognostic (2.28e-1)" "potential prognostic unfavorable (4.15e-4)" "unprognostic (1.30e-1)" "unprognostic (1.39e-1)" "unprognostic (5.89e-2)" "potential prognostic favorable (2.30e-4)" "unprognostic (9.61e-2)" "unprognostic (1.89e-1)" "unprognostic (5.28e-2)" "unprognostic (6.71e-2)" "unprognostic (1.80e-1)" "unprognostic (1.81e-3)" "unprognostic (1.25e-2)" "unprognostic (1.17e-1)" "unprognostic (9.61e-2)" "unprognostic (7.29e-2)" "unprognostic (1.03e-1)" "unprognostic (3.78e-1)" "unprognostic (2.16e-2)" "unprognostic (8.81e-2)" "unprognostic (4.81e-1)" "unprognostic (2.05e-1)" "unprognostic (1.53e-3)" "unprognostic (6.65e-2)" "unprognostic (2.98e-1)" "unprognostic (9.82e-2)" "unprognostic (3.82e-3)" "unprognostic (1.02e-1)" MEGF8 "C19orf49, EGFL4, FLJ22365, SBP1" ENSG00000105429 "Multiple EGF like domains 8" Q7Z7M0 19 42325609-42378769 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Retinal amacrine cells: 55.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049248 Approved NA NA 88000000 "Cluster 10: Brain - Synaptic signal transduction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 4: Non-specific - Transcription" "Cluster 109: Neurons - Neuronal signaling" 5 "HPA049248: " "unprognostic (1.69e-2)" "unprognostic (8.77e-2)" "unprognostic (1.30e-1)" "potential prognostic unfavorable (1.59e-4)" "unprognostic (2.36e-1)" "unprognostic (6.07e-2)" "unprognostic (8.56e-2)" "unprognostic (8.62e-2)" "unprognostic (3.69e-2)" "unprognostic (1.30e-1)" "potential prognostic favorable (3.58e-4)" "unprognostic (2.44e-2)" "unprognostic (2.15e-2)" "unprognostic (2.72e-2)" "unprognostic (1.14e-1)" "potential prognostic unfavorable (4.92e-4)" "unprognostic (2.98e-1)" "unprognostic (1.51e-1)" "unprognostic (3.62e-1)" "unprognostic (4.02e-2)" "unprognostic (2.94e-1)" "unprognostic (4.23e-3)" "unprognostic (5.83e-2)" "unprognostic (1.57e-1)" "unprognostic (1.81e-1)" "unprognostic (2.77e-1)" "unprognostic (1.02e-1)" "unprognostic (2.81e-1)" "unprognostic (8.84e-2)" "unprognostic (1.09e-2)" "unprognostic (1.67e-1)" MEGF9 EGFL5 ENSG00000106780 "Multiple EGF like domains 9" Q9H1U4 9 120600811-120714470 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 63.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 742.9;Bergmann glia: 546.9;Cone photoreceptor cells: 857.0;Neutrophil progenitors: 1339.0;Neutrophils: 2749.6;Retinal pigment epithelial cells: 511.6" "Cell type enhanced" "Detected in all" "Bergmann glia: 619.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 25.2" "Group enriched" "Detected in many" 5 "granulocytes: 25.2;monocytes: 7.4" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Colon - Enteric glia cells, Liver - Hepatocytes, Spleen - Neutrophils_2, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014319, HPA050238" Approved Approved Nucleoplasm,Cytosol NA NA 8500000 "Cluster 21: Neutrophils - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 1 Nucleoplasm Cytosol "HPA014319: , HPA050238: " "unprognostic (7.85e-2)" "unprognostic (8.74e-2)" "unprognostic (4.61e-1)" "unprognostic (3.64e-1)" "unprognostic (2.02e-1)" "unprognostic (2.32e-3)" "unprognostic (1.63e-1)" "unprognostic (1.80e-1)" "unprognostic (2.43e-1)" "unprognostic (6.39e-2)" "validated prognostic favorable (6.94e-10)" "validated prognostic favorable (5.62e-5)" "unprognostic (6.08e-2)" "unprognostic (1.27e-1)" "unprognostic (5.57e-2)" "unprognostic (3.12e-2)" "unprognostic (3.22e-2)" "unprognostic (1.45e-1)" "unprognostic (3.92e-2)" "unprognostic (2.21e-2)" "unprognostic (1.36e-1)" "unprognostic (5.97e-2)" "unprognostic (1.19e-1)" "unprognostic (3.08e-2)" "unprognostic (6.48e-2)" "unprognostic (2.05e-1)" "unprognostic (1.60e-2)" "unprognostic (9.70e-3)" "unprognostic (2.09e-1)" "unprognostic (7.42e-2)" "unprognostic (2.95e-2)" MEI1 "MGC40042, SPATA38" ENSG00000167077 "Meiotic double-stranded break formation protein 1" Q5TIA1 22 41699503-41799456 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Meiosis "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 20.7;testis: 36.6" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 125.8;Early primary spermatocytes: 296.5;Early spermatids: 96.7;Late spermatids: 74.5;Neutrophils: 45.8;Plasma cells: 219.5" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 27.9;midbrain-derived inhibitory: 36.5" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 23.3" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Myeloma: 13.7" "Breast - Plasma cells, Minor Salivary Gland - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells" "Low region specificity" "Detected in many" "Region enriched" "Detected in single" 4 "olfactory bulb: 2.3" HPA049240 Approved NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 47: Testis - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 67: Plasma cells - Plasma cell differentiation" "HPA049240: " "unprognostic (3.71e-2)" "unprognostic (1.19e-3)" "unprognostic (1.69e-1)" "potential prognostic favorable (1.45e-7)" "unprognostic (8.34e-2)" "unprognostic (4.38e-2)" "unprognostic (4.20e-3)" "potential prognostic favorable (8.55e-4)" "potential prognostic unfavorable (6.26e-4)" "unprognostic (4.92e-2)" "unprognostic (1.31e-1)" "unprognostic (1.47e-1)" "unprognostic (2.46e-2)" "potential prognostic favorable (7.97e-4)" "unprognostic (2.87e-2)" "unprognostic (1.32e-1)" "unprognostic (1.03e-1)" "unprognostic (8.39e-3)" "unprognostic (9.86e-2)" "unprognostic (4.90e-2)" "unprognostic (4.29e-2)" "unprognostic (2.01e-1)" "unprognostic (1.93e-2)" "unprognostic (2.28e-1)" "unprognostic (4.94e-3)" "unprognostic (1.00e-1)" "unprognostic (1.91e-1)" "unprognostic (1.83e-1)" "unprognostic (6.61e-2)" MEI4 ENSG00000269964 "Meiotic double-stranded break formation protein 4" A8MW99 6 77650274-77927045 "Predicted intracellular proteins" "DNA recombination, Meiosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 3.9;pancreas: 1.9;testis: 3.2;thyroid gland: 2.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 51.0;Corticotrophs: 37.9;Differentiating spermatogonia: 36.6;Early primary spermatocytes: 36.3;Early spermatids: 76.2;Gonadotrophs: 78.0;Hematopoietic stem cells: 41.7;Lactotrophs: 38.8;Late primary spermatocytes: 108.4;Proximal tubule cells: 68.7;Sertoli cells: 85.0;Somatotrophs: 60.7;Thyrotrophs: 49.3" "Cell type enhanced" "Detected in many" "lower rhombic lip: 80.7" "Cancer enhanced" "Detected in some" "Kidney Renal Clear Cell Carcinoma (TCGA): 1.7;Testicular Germ Cell Tumor (TCGA): 1.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 49: Hindbrain - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 33 "potential prognostic favorable (1.04e-4)" "unprognostic (2.58e-2)" "unprognostic (2.72e-2)" MEIG1 "bA2K17.3, SPATA39" ENSG00000197889 "Meiosis/spermiogenesis associated 1" Q5JSS6 10 14959388-14988050 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "fallopian tube: 3.4;testis: 9.5" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 19.0;Early spermatids: 115.7;Endometrial ciliated cells: 32.5;Ependymal cells: 24.6;Epididymal efferent duct ciliated cells: 19.3;Fallopian tube ciliated cells: 45.0;Late primary spermatocytes: 164.3;Late spermatids: 19.1;Respiratory ciliated cells: 54.3" "Cell type enriched" "Detected in many" 4 "ependymal cell: 28.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.4" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in single" "Lung - Respiratory ciliated cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 107: Ciliated cells - Cilia assembly & function" "unprognostic (1.00e-1)" "unprognostic (4.23e-1)" "unprognostic (1.83e-2)" "unprognostic (1.26e-1)" "unprognostic (2.95e-1)" "unprognostic (2.41e-1)" MEIKIN SPO13 ENSG00000239642 "Meiotic kinetochore factor" A0A087WXM9 5 131806990-131945698 "Predicted intracellular proteins" "Chromosome partition, Meiosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "testis: 5.5" "Group enriched" "Detected in some" 5 "Astrocytes: 191.0;Bergmann glia: 196.8" "Cell type enhanced" "Detected in many" "astrocyte: 173.7;Bergmann glia: 188.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 67: Testis - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 28: Astrocytes - Homeostasis & neuron support" 2 MEIOB "C16orf73, MGC35212" ENSG00000162039 "Meiosis specific with OB-fold" Q8N635 16 1833986-1872178 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Meiosis "DNA-binding, Exonuclease, Hydrolase, Nuclease" "Disease variant, Premature ovarian failure" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 31 "testis: 26.5" "Cell type enriched" "Detected in some" 14 "Early primary spermatocytes: 98.3" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 2.2;Testicular Germ Cell Tumor (TCGA): 7.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 19.3;Rhabdoid: 21.3" "Adipose visceral - Mesothelial cells, Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 4: Non-specific - Transcription" "Cluster 3: Early primary spermatocytes - Early meiosis" 1 "unprognostic (1.90e-1)" "unprognostic (2.27e-1)" "unprognostic (6.86e-2)" "unprognostic (1.73e-1)" MEIOC "C17orf104, FLJ35848" ENSG00000180336 "Meiosis specific with coiled-coil domain" A2RUB1 17 44656404-44690308 "Predicted intracellular proteins" Meiosis "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "testis: 44.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 76.3;Differentiating spermatogonia: 80.0;Early primary spermatocytes: 302.8;Early spermatids: 348.5;Late primary spermatocytes: 139.1;Late spermatids: 929.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "Adrenocortical cancer: 64.2" "Testis - Early spermatids, Testis - Late spermatids, Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA027266 Enhanced Uncertain "Cell Junctions" NA NA "Cluster 67: Testis - Mixed function" "Cluster 34: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" "Cell Junctions" "HPA027266: " "unprognostic (6.14e-2)" "unprognostic (5.98e-2)" "unprognostic (2.42e-3)" "unprognostic (5.59e-2)" "unprognostic (1.16e-1)" "unprognostic (3.61e-1)" "potential prognostic favorable (8.01e-4)" "unprognostic (1.50e-2)" "unprognostic (1.38e-1)" "unprognostic (1.94e-2)" MEIOSIN "BHMG1, HMGDC" ENSG00000237452 "Meiosis initiator" C9JSJ3 19 45733439-45764541 "Predicted intracellular proteins" "Meiosis, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 23 "testis: 7.5" "Group enriched" "Detected in some" 21 "Differentiating spermatogonia: 35.2;Early primary spermatocytes: 82.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Spermatocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA049521 Uncertain Approved Nucleoplasm NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 3: Early primary spermatocytes - Early meiosis" Nucleoplasm "HPA049521: " MEIS1 ENSG00000143995 "Meis homeobox 1" O00470 2 66433452-66573869 "Predicted intracellular proteins, Transcription factors" Transcription "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 708.9;Endometrial stromal cells: 713.0;Hematopoietic stem cells: 994.7;Lacrimal acinar cells: 902.2;Megakaryocyte progenitors: 607.8;Mesothelial cells: 520.0;Rod photoreceptor cells: 591.2;Salivary acinar cells: 508.7" "Cell type enhanced" "Detected in many" "Bergmann glia: 402.4;oligodendrocyte: 348.5;upper rhombic lip: 403.4" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 64.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 1.6;plasmacytoid DC: 1.3" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Neuroblastoma: 38.0" "Breast - Fibroblasts, Kidney - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011521, HPA056000, HPA058641" Approved Supported Nucleoplasm NA NA "Cluster 41: Basophils - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 108: Fibroblasts - ECM organization" 6 Nucleoplasm "CAB011521: , HPA056000: , HPA058641: " "unprognostic (3.26e-2)" "unprognostic (1.58e-1)" "unprognostic (5.70e-3)" "unprognostic (2.16e-1)" "unprognostic (1.32e-1)" "unprognostic (7.05e-2)" "unprognostic (4.02e-1)" "unprognostic (7.36e-2)" "potential prognostic favorable (3.56e-5)" "unprognostic (1.22e-1)" "validated prognostic favorable (8.24e-4)" "validated prognostic favorable (6.10e-4)" "unprognostic (7.30e-3)" "unprognostic (1.15e-2)" "unprognostic (5.55e-3)" "unprognostic (3.03e-2)" "unprognostic (7.37e-2)" "unprognostic (3.34e-2)" "unprognostic (3.69e-1)" "unprognostic (2.98e-1)" "unprognostic (2.59e-1)" "unprognostic (7.08e-2)" "unprognostic (2.34e-2)" "unprognostic (4.97e-2)" "unprognostic (4.65e-1)" "unprognostic (2.20e-2)" "unprognostic (6.46e-2)" "unprognostic (2.51e-1)" "unprognostic (2.21e-1)" "unprognostic (2.60e-1)" MEIS2 "HsT18361, MRG1" ENSG00000134138 "Meis homeobox 2" O14770 15 36889204-37101299 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 45.2" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 973.3;Basal prostatic cells: 1124.9;Ependymal cells: 932.7;Lacrimal acinar cells: 1208.4;Medullary thymic epithelial cells: 1202.5;Mesothelial cells: 927.7;Pituitary stem cells: 1518.9;Prostatic club cells: 906.4;Retinal amacrine cells: 964.5;Salivary acinar cells: 1385.0;Salivary ionocytes: 1052.4;Somatotrophs: 889.7" "Cell type enhanced" "Detected in many" "eccentric medium spiny neuron: 2454.7;medium spiny neuron: 1513.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Neuroblastoma: 78.2" "Minor Salivary Gland - Minor salivary gland ductal cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basal ganglia: 92.1;olfactory bulb: 241.8" "HPA003256, CAB004999" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 33: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 7 Nucleoplasm Cytosol "CAB004999: , HPA003256: " "potential prognostic favorable (6.41e-5)" "unprognostic (6.60e-2)" "unprognostic (7.55e-2)" "potential prognostic favorable (2.44e-5)" "unprognostic (8.77e-2)" "unprognostic (2.88e-2)" "unprognostic (2.41e-1)" "unprognostic (3.95e-3)" "unprognostic (2.71e-1)" "unprognostic (1.15e-1)" "potential prognostic favorable (2.92e-5)" "unprognostic (2.77e-3)" "potential prognostic unfavorable (2.24e-5)" "unprognostic (1.91e-2)" "unprognostic (1.23e-2)" "unprognostic (4.63e-2)" "unprognostic (7.11e-2)" "unprognostic (4.06e-2)" "unprognostic (4.02e-2)" "unprognostic (1.95e-1)" "unprognostic (5.99e-2)" "unprognostic (1.59e-1)" "unprognostic (5.57e-2)" "unprognostic (1.44e-2)" "unprognostic (2.55e-3)" "unprognostic (8.32e-2)" "unprognostic (9.83e-2)" "unprognostic (6.63e-2)" "unprognostic (1.18e-1)" "potential prognostic unfavorable (2.12e-4)" "unprognostic (2.72e-2)" MEIS3 "DKFZp547H236, MRG2" ENSG00000105419 "Meis homeobox 3" Q99687 19 47403124-47419527 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 115.2;endometrium 1: 79.8" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 58.1;Early spermatids: 81.0;Endometrial stromal cells: 32.6;Late spermatids: 101.7;Other brain neurons: 44.0;Pancreatic islet cells: 36.6;Retinal amacrine cells: 61.6;Retinal horizontal cells: 40.1;Smooth muscle cells: 59.3" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 59.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 71.0" "Adipose visceral - Adipose progenitor cells, Heart muscle - Fibroblasts, Lung - Fibroblasts_2, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046699 Uncertain Approved Nucleoplasm NA NA "Cluster 65: Brain - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" Nucleoplasm "HPA046699: " "unprognostic (2.42e-3)" "unprognostic (1.89e-2)" "unprognostic (1.11e-1)" "unprognostic (6.28e-2)" "unprognostic (1.27e-2)" "unprognostic (1.46e-1)" "unprognostic (7.99e-2)" "unprognostic (4.30e-2)" "unprognostic (2.34e-2)" "unprognostic (1.46e-1)" "unprognostic (2.26e-2)" "unprognostic (2.68e-2)" "unprognostic (2.10e-1)" "unprognostic (6.19e-2)" "unprognostic (6.81e-2)" "unprognostic (3.63e-3)" "unprognostic (4.93e-2)" "unprognostic (4.23e-2)" "unprognostic (2.04e-1)" "unprognostic (7.35e-3)" "unprognostic (2.84e-2)" "unprognostic (3.29e-2)" "unprognostic (1.66e-1)" "unprognostic (3.11e-1)" "unprognostic (7.16e-2)" "unprognostic (2.61e-2)" "unprognostic (2.06e-1)" "unprognostic (2.73e-3)" "unprognostic (1.31e-1)" "unprognostic (6.36e-3)" "unprognostic (2.45e-1)" MELK KIAA0175 ENSG00000165304 "Maternal embryonic leucine zipper kinase" Q14680 9 36572862-36677683 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 9.6;lymphoid tissue: 19.6" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 64.9;Early primary spermatocytes: 76.6;Enteric transient amplifying cells: 41.1;Erythrocyte progenitors: 110.7;Esophageal basal cells: 43.0;Extravillous trophoblasts: 81.6;Gastric progenitor cells: 39.7;Megakaryocyte progenitors: 38.2;Migrating cytotrophoblasts: 47.7;Monocyte progenitors: 117.7;Neutrophil progenitors: 44.3;Respiratory deuterosomal cells: 41.5;Sertoli cells: 117.6;Undifferentiated spermatogonia: 36.3" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 4 "T-reg: 1.7" "Lineage enriched" "Detected in single" 4 "T-cells: 1.7" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA017214 Uncertain NA Yes "Cluster 25: Non-specific - Unknown function" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Non-specific - Cell proliferation" 29 "HPA017214: " "unprognostic (6.15e-3)" "unprognostic (5.99e-2)" "unprognostic (1.06e-1)" "unprognostic (2.41e-1)" "unprognostic (5.67e-2)" "unprognostic (1.85e-1)" "unprognostic (2.17e-1)" "unprognostic (3.82e-2)" "unprognostic (1.68e-1)" "potential prognostic unfavorable (2.10e-4)" "validated prognostic unfavorable (3.31e-6)" "validated prognostic unfavorable (6.54e-7)" "potential prognostic unfavorable (6.15e-6)" "validated prognostic unfavorable (8.63e-7)" "validated prognostic unfavorable (6.82e-6)" "validated prognostic unfavorable (9.50e-5)" "validated prognostic unfavorable (5.78e-5)" "unprognostic (1.11e-1)" "unprognostic (3.61e-2)" "unprognostic (5.76e-2)" "unprognostic (1.76e-2)" "potential prognostic unfavorable (6.60e-4)" "unprognostic (2.22e-3)" "unprognostic (1.19e-1)" "unprognostic (7.49e-2)" "unprognostic (2.11e-1)" "unprognostic (6.47e-2)" "unprognostic (6.55e-3)" "unprognostic (1.62e-1)" "unprognostic (4.23e-2)" MELTF "CD228, FLJ38863, MAP97, MFI2, MGC4856, MTf, MTF1" ENSG00000163975 Melanotransferrin P08582 3 196980590-197029835 "CD markers, Plasma proteins, Predicted intracellular proteins" "Ion transport, Iron transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 37.8;salivary gland: 67.1" "Cell type enhanced" "Detected in many" "Breast secretory cells: 55.6;Epicardial cells: 66.0;Lacrimal acinar cells: 125.0;Loop of henle epithelial cells: 50.5;Mast cells: 104.1;pDCs: 47.3;Respiratory deuterosomal cells: 53.9;Salivary acinar cells: 70.4" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 38.4;pericyte: 93.3" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 129.7" "Region enhanced" "Detected in all" "choroid plexus: 63.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "skin cancer: 190.5" "Adrenal gland - Adrenal medulla cells, Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Fibroblasts, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA004880 Approved "Intracellular and membrane" Transport NA NA 130000000 "Cluster 72: Kidney - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 58: Mast cells - Allergic inflammatory responses" 28 "HPA004880: " "unprognostic (2.06e-2)" "unprognostic (7.92e-3)" "unprognostic (3.18e-2)" "unprognostic (1.12e-1)" "unprognostic (1.05e-1)" "unprognostic (9.25e-2)" "unprognostic (1.13e-2)" "unprognostic (3.81e-2)" "potential prognostic unfavorable (7.74e-4)" "potential prognostic unfavorable (1.88e-10)" "unprognostic (7.00e-3)" "unprognostic (7.12e-2)" "unprognostic (6.82e-2)" "potential prognostic unfavorable (1.67e-5)" "unprognostic (2.32e-2)" "unprognostic (5.08e-2)" "unprognostic (3.17e-1)" "unprognostic (7.77e-2)" "unprognostic (1.61e-1)" "unprognostic (2.12e-3)" "potential prognostic unfavorable (1.61e-4)" "unprognostic (1.91e-1)" "unprognostic (8.60e-3)" "unprognostic (3.20e-1)" "unprognostic (1.12e-2)" "unprognostic (1.06e-1)" "unprognostic (1.77e-1)" "unprognostic (3.08e-2)" "unprognostic (2.61e-1)" MEMO1 "C2orf4, CGI-27, MEMO" ENSG00000162959 "Mediator of cell motility 1" Q9Y316 2 31865060-32011230 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Astrocytes: 116.5;Bergmann glia: 144.3;Brain excitatory neurons: 176.5;Brain inhibitory neurons: 174.1;Choroid plexus epithelial cells: 141.6;Ependymal cells: 114.1;Microglia: 409.4;Oligodendrocyte progenitor cells: 159.7;Oligodendrocytes: 168.9;Other brain neurons: 175.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042603, HPA057952" Approved Approved Vesicles NA NA 15000 "Cluster 25: Non-specific - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 22: Non-specific - Basic cellular functions" 18 Vesicles "HPA042603: , HPA057952: " "unprognostic (9.82e-3)" "unprognostic (3.81e-2)" "unprognostic (1.39e-1)" "unprognostic (1.18e-1)" "unprognostic (3.19e-2)" "potential prognostic favorable (3.51e-4)" "unprognostic (1.79e-1)" "unprognostic (3.82e-3)" "unprognostic (2.16e-3)" "unprognostic (3.24e-2)" "unprognostic (1.57e-2)" "unprognostic (3.26e-2)" "unprognostic (4.20e-2)" "validated prognostic unfavorable (1.81e-7)" "validated prognostic unfavorable (8.13e-5)" "unprognostic (1.50e-1)" "unprognostic (9.47e-3)" "unprognostic (8.48e-2)" "unprognostic (9.85e-2)" "unprognostic (6.67e-2)" "unprognostic (9.61e-2)" "unprognostic (4.43e-2)" "unprognostic (3.45e-2)" "unprognostic (1.05e-2)" "unprognostic (7.75e-2)" "unprognostic (3.26e-1)" "unprognostic (9.34e-2)" "unprognostic (2.41e-1)" "unprognostic (2.05e-1)" "unprognostic (4.32e-2)" "unprognostic (6.93e-3)" MEN1 ENSG00000133895 "Menin 1" O00255 11 64803510-64811294 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Repressor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Megakaryocytes: 37.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030342 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 70: Non-specific - Protein processing" "Cluster 33: Neurons - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 177 Nucleoplasm Cytosol "HPA030342: " "unprognostic (4.50e-2)" "unprognostic (6.41e-3)" "potential prognostic favorable (5.61e-4)" "unprognostic (1.09e-2)" "unprognostic (1.09e-1)" "unprognostic (1.74e-1)" "unprognostic (3.91e-2)" "unprognostic (3.66e-2)" "unprognostic (3.70e-1)" "unprognostic (1.88e-3)" "potential prognostic favorable (1.24e-4)" "unprognostic (3.27e-2)" "unprognostic (1.78e-1)" "potential prognostic unfavorable (1.51e-5)" "unprognostic (1.10e-1)" "unprognostic (4.09e-2)" "potential prognostic unfavorable (8.79e-4)" "unprognostic (7.21e-2)" "unprognostic (2.14e-2)" "unprognostic (3.40e-1)" "unprognostic (2.12e-1)" "unprognostic (4.17e-1)" "unprognostic (1.23e-1)" "unprognostic (4.48e-1)" "unprognostic (3.11e-2)" "unprognostic (2.24e-1)" "unprognostic (2.30e-1)" "potential prognostic favorable (1.40e-4)" "unprognostic (1.57e-1)" "unprognostic (1.27e-1)" "unprognostic (1.52e-1)" MEOX1 MOX1 ENSG00000005102 "Mesenchyme homeobox 1" P50221 17 43640389-43661922 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 31.3;breast: 22.5;heart muscle: 22.4" "Cell type enriched" "Detected in some" 9 "Vascular endothelial cells: 62.3" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 11.1" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in some" 4 "T-reg: 17.5" "Lineage enriched" "Detected in single" 48 "T-cells: 17.5" "Group enriched" "Detected in many" 6 "ovarian cancer: 14.0;Rhabdoid: 19.9;Sarcoma: 5.1;Uterine cancer: 11.1" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Lung - Fibroblasts_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA045214, HPA063788" Uncertain Approved "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 53: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 81 Nucleoplasm "Cytokinetic bridge, Cytosol" "HPA045214: , HPA063788: " "unprognostic (1.54e-1)" "unprognostic (1.60e-2)" "unprognostic (2.01e-3)" "unprognostic (2.77e-3)" "unprognostic (5.10e-2)" "unprognostic (3.14e-1)" "unprognostic (8.01e-2)" "unprognostic (7.81e-3)" "unprognostic (7.90e-2)" "unprognostic (7.95e-2)" "unprognostic (2.17e-2)" "unprognostic (2.63e-1)" "unprognostic (1.24e-1)" "unprognostic (1.15e-1)" "unprognostic (3.23e-1)" "unprognostic (6.91e-2)" "unprognostic (2.25e-1)" "unprognostic (7.39e-2)" "unprognostic (1.52e-1)" "unprognostic (1.10e-1)" "unprognostic (1.28e-1)" "unprognostic (1.41e-1)" MEOX2 "GAX, MOX2" ENSG00000106511 "Mesenchyme homeobox 2" P50222 7 15611212-15686683 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 38.4;blood vessel: 30.8;placenta: 39.6" "Cell type enhanced" "Detected in some" "Fibro-adipogenic progenitors: 329.8;Fibroblasts: 37.5;Leydig cells: 120.7;Mesothelial cells: 171.1;Pericytes: 100.0;Peritubular myoid cells: 59.8;Vascular endothelial cells: 149.2;Vascular smooth muscle cells: 100.1" "Group enriched" "Detected in many" 5 "astrocyte: 17.7;fibroblast: 57.0;vascular associated smooth muscle cell: 23.0" "Cancer enriched" "Detected in many" 8 "Glioblastoma Multiforme (TCGA): 26.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 13 "Rhabdoid: 83.0" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "medulla oblongata: 4.5;spinal cord: 12.6" HPA053793 Enhanced NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 19: Astrocytes - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 172 "HPA053793: " "unprognostic (4.00e-1)" "unprognostic (1.80e-1)" "unprognostic (5.78e-2)" "unprognostic (1.34e-2)" "unprognostic (2.20e-1)" "unprognostic (5.80e-2)" "potential prognostic unfavorable (6.42e-7)" "unprognostic (1.38e-2)" "unprognostic (2.50e-2)" "unprognostic (1.34e-1)" "unprognostic (1.09e-2)" "unprognostic (1.12e-1)" "unprognostic (7.46e-2)" "unprognostic (9.54e-2)" "potential prognostic unfavorable (1.19e-6)" "unprognostic (4.78e-1)" "unprognostic (1.71e-2)" "unprognostic (2.53e-2)" "unprognostic (1.21e-1)" "unprognostic (1.46e-2)" "potential prognostic unfavorable (2.86e-4)" "unprognostic (2.27e-1)" "unprognostic (5.70e-2)" MEP1A PPHA ENSG00000112818 "Meprin A subunit alpha" Q16819 6 46793389-46839778 "Enzymes, Plasma proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 101 "intestine: 440.6" "Cell type enriched" "Detected in some" 4 "Enterocytes: 969.2" "Group enriched" "Detected in some" 15 "central nervous system macrophage: 7.9;ependymal cell: 2.5" "Group enriched" "Detected in some" 5 "Colon Adenocarcinoma (TCGA): 51.1;Rectum Adenocarcinoma (TCGA): 63.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "colorectal cancer: 8.0;Gastric cancer: 3.2;liver cancer: 9.0" "Colon - Colon enterocytes, Skin - Sebaceous gland cells, Testis - Early spermatids, Testis - Late spermatids" "CAB025163, HPA029416" Enhanced NA NA 1000000 "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 1: Enterocytes - Absorption and Digestion" 1 "CAB025163: , HPA029416: " "unprognostic (4.94e-2)" "unprognostic (2.41e-1)" "unprognostic (7.96e-3)" "potential prognostic unfavorable (3.61e-7)" "unprognostic (9.99e-2)" "unprognostic (2.14e-1)" "unprognostic (7.10e-2)" "unprognostic (2.29e-3)" "unprognostic (2.71e-1)" "unprognostic (1.99e-2)" MEP1B ENSG00000141434 "Meprin A subunit beta" Q16820 18 32185069-32220404 "Enzymes, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Inflammatory response" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 56 "intestine: 342.8" "Group enriched" "Detected in many" 9 "Cardiomyocytes: 99.6;Enterocytes: 282.4" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in single" 5 "Pancreatic Adenocarcinoma (TCGA): 4.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "colorectal cancer: 3.1;Myeloma: 2.3" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029119 Enhanced "Secreted to digestive system" Enzyme NA NA 290000 "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 9: Non-specific - Receptor signaling" "Cluster 40: Non-specific - Unknown function" "Cluster 1: Enterocytes - Absorption and Digestion" 4 "HPA029119: " "unprognostic (2.19e-1)" "unprognostic (1.01e-1)" MEPCE "BCDIN3, FLJ20257" ENSG00000146834 "Methylphosphate capping enzyme" Q7L2J0 7 100428322-100434126 "Essential proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ependymal cells: 9.9;Epididymal basal cells: 13.8;Epididymal efferent duct ciliated cells: 10.9;Platelets: 17.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026384, HPA051587" Supported Approved "Nucleoplasm,Cell Junctions" NA Yes "Cluster 30: Non-specific - DNA binding" "Cluster 67: Testis - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 39: Non-specific - Transcription" "Cluster 102: Non-specific - Mixed function" 200 Nucleoplasm "Cell Junctions" "CAB026384: , HPA051587: " "unprognostic (9.32e-2)" "unprognostic (5.44e-2)" "unprognostic (6.82e-2)" "unprognostic (1.79e-1)" "unprognostic (2.13e-2)" "unprognostic (2.14e-1)" "unprognostic (2.16e-1)" "unprognostic (2.37e-1)" "unprognostic (1.08e-1)" "unprognostic (3.22e-1)" "potential prognostic favorable (1.22e-6)" "unprognostic (2.46e-2)" "potential prognostic favorable (5.34e-6)" "unprognostic (2.69e-3)" "unprognostic (2.45e-3)" "unprognostic (2.16e-2)" "unprognostic (1.00e-1)" "unprognostic (3.23e-3)" "unprognostic (7.17e-2)" "unprognostic (2.16e-1)" "unprognostic (5.92e-1)" "unprognostic (1.88e-2)" "unprognostic (4.12e-1)" "unprognostic (1.57e-1)" "unprognostic (6.74e-2)" "unprognostic (2.39e-2)" "unprognostic (8.67e-2)" "unprognostic (4.95e-1)" "unprognostic (2.79e-1)" "unprognostic (4.25e-1)" "unprognostic (1.73e-1)" MEPE ENSG00000152595 "Matrix extracellular phosphoglycoprotein" Q9NQ76 4 87821398-87846814 "Predicted intracellular proteins, Predicted secreted proteins" Biomineralization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 55 "brain: 5.4" "Group enriched" "Detected in some" 4 "Other brain neurons: 17.8;Respiratory ciliated cells: 6.6" "Group enriched" "Detected in some" 4 "amygdala excitatory: 5.3;MGE interneuron: 19.9" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "amygdala: 15.8;cerebral cortex: 55.6;hypothalamus: 17.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells" "Not detected" "Not detected" "Region enhanced" "Detected in single" "amygdala: 1.0" "HPA038003, HPA038004" Uncertain "Secreted to extracellular matrix" Other NA NA 1700000 "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 109: Neurons - Neuronal signaling" 3 "HPA038003: , HPA038004: " "unprognostic (3.42e-1)" "unprognostic (1.83e-1)" MERTK "c-Eyk, mer, RP38, Tyro12" ENSG00000153208 "MER proto-oncogene, tyrosine kinase" Q12866 2 111898607-112029561 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Disease variant, Proto-oncogene, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 89.9" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 246.3;Astrocytes: 223.7;Bergmann glia: 193.1;Choroid plexus epithelial cells: 188.0;Kupffer cells: 732.8;Macrophages: 427.7;Microglia: 378.9;monocytes: 167.3;Pituicytes/FSCs: 247.6" "Cell type enhanced" "Detected in many" "Bergmann glia: 214.6;central nervous system macrophage: 478.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 11 "intermediate monocyte: 8.7;non-classical monocyte: 5.5" "Lineage enriched" "Detected in single" 50 "monocytes: 8.7" "Low cancer specificity" "Detected in many" "Adipose visceral - Macrophages, Heart muscle - Macrophages, Minor Salivary Gland - Macrophages, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036196, HPA075622" Enhanced Supported "Plasma membrane,Midbody,Cytosol,Acrosome,Mid piece,Principal piece" Yes NA 8400000 "Cluster 40: Monocytes - Innate immune response" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 11 "Plasma membrane" "Midbody, Cytosol, Acrosome, Mid piece, Principal piece" "HPA036196: , HPA075622: " "unprognostic (3.26e-1)" "unprognostic (2.03e-2)" "unprognostic (1.92e-1)" "potential prognostic favorable (8.83e-4)" "unprognostic (1.92e-2)" "unprognostic (1.05e-1)" "unprognostic (6.18e-2)" "unprognostic (6.39e-2)" "unprognostic (1.50e-1)" "unprognostic (1.20e-3)" "potential prognostic favorable (2.36e-6)" "unprognostic (6.69e-3)" "unprognostic (3.02e-1)" "unprognostic (7.89e-3)" "unprognostic (6.29e-3)" "unprognostic (1.14e-2)" "unprognostic (3.75e-2)" "unprognostic (1.59e-2)" "unprognostic (2.33e-2)" "unprognostic (1.12e-1)" "unprognostic (1.14e-1)" "unprognostic (1.42e-1)" "unprognostic (6.60e-2)" "unprognostic (4.06e-1)" "unprognostic (1.06e-1)" "unprognostic (5.20e-2)" "unprognostic (2.60e-1)" "unprognostic (1.63e-2)" "unprognostic (3.24e-1)" "unprognostic (1.40e-1)" "unprognostic (3.71e-2)" MESD "BOCA, KIAA0081, MESDC2" ENSG00000117899 "Mesoderm development LRP chaperone" Q14696 15 80946289-80989828 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Wnt signaling pathway" Chaperone "Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 411.3;Epididymal principal cells: 383.9;Extravillous trophoblasts: 336.6;Migrating cytotrophoblasts: 345.3;Syncytiotrophoblasts: 529.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039414, HPA041721" Approved Supported "Nuclear bodies,Endoplasmic reticulum,Cytosol" "Intracellular and membrane" Other NA NA 9300000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 22: Epididymis - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" 64 "Endoplasmic reticulum" "Nuclear bodies, Cytosol" "HPA039414: , HPA041721: " "unprognostic (1.15e-1)" "unprognostic (2.77e-2)" "unprognostic (2.62e-3)" "unprognostic (1.12e-1)" "unprognostic (5.65e-2)" "unprognostic (9.73e-2)" "unprognostic (7.64e-2)" "unprognostic (3.44e-3)" "unprognostic (1.62e-2)" "potential prognostic favorable (6.48e-4)" "unprognostic (9.55e-3)" "unprognostic (1.70e-1)" "unprognostic (3.89e-2)" "potential prognostic unfavorable (2.53e-5)" "unprognostic (3.02e-2)" "unprognostic (1.96e-1)" "unprognostic (2.84e-1)" "unprognostic (8.88e-3)" "unprognostic (1.71e-2)" "unprognostic (3.49e-2)" "unprognostic (2.74e-3)" "unprognostic (3.65e-2)" "unprognostic (2.40e-1)" "unprognostic (6.41e-2)" "unprognostic (7.02e-2)" "unprognostic (1.57e-1)" "unprognostic (1.15e-1)" "unprognostic (1.75e-1)" "unprognostic (1.62e-2)" MESP1 "bHLHc5, MGC10676" ENSG00000166823 "Mesoderm posterior bHLH transcription factor 1" Q9BRJ9 15 89749875-89751249 "Predicted intracellular proteins, Transcription factors" "Notch signaling pathway, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 15.4;prostate: 21.4;skeletal muscle: 12.8" "Cell type enhanced" "Detected in many" "Breast lactating cells: 65.3;Breast secretory cells: 100.0;Oocytes: 170.4;Prostatic glandular cells: 76.2;Respiratory secretory cells: 61.2;Salivary duct cells: 56.3" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in many" 5 "Prostate Adenocarcinoma (TCGA): 16.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 23.8" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA069981 Supported Nucleoplasm,Nucleoli NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 3 Nucleoplasm Nucleoli "HPA069981: " "unprognostic (1.80e-2)" "unprognostic (1.11e-2)" "unprognostic (2.66e-1)" "unprognostic (7.42e-2)" "unprognostic (4.03e-3)" "unprognostic (9.11e-2)" "unprognostic (2.07e-1)" "unprognostic (4.05e-3)" "potential prognostic unfavorable (1.71e-4)" "unprognostic (1.90e-2)" "unprognostic (2.77e-1)" "unprognostic (1.66e-1)" "unprognostic (2.85e-1)" "unprognostic (5.20e-2)" "unprognostic (1.21e-1)" MESP2 "bHLHc6, SCDO2" ENSG00000188095 "Mesoderm posterior bHLH transcription factor 2" Q0VG99 15 89760591-89778754 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Notch signaling pathway, Transcription, Transcription regulation" "Developmental protein, DNA-binding" Dwarfism "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Breast secretory cells: 8.4;Cone photoreceptor cells: 22.8;Lacrimal acinar cells: 4.5;Oocytes: 4.6;Papillary tip epithelial cells: 4.9;Rod photoreceptor cells: 37.9" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Minor Salivary Gland - Minor salivary glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 24: Neurons - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 79: Photoreceptor cells - Phototransduction" "unprognostic (2.25e-1)" "unprognostic (3.96e-2)" "unprognostic (1.08e-1)" "unprognostic (2.33e-1)" "unprognostic (2.67e-2)" "unprognostic (1.51e-3)" "unprognostic (6.92e-2)" "unprognostic (1.58e-1)" "unprognostic (7.74e-2)" "unprognostic (3.30e-1)" "unprognostic (2.77e-1)" "unprognostic (2.87e-1)" "unprognostic (8.58e-2)" MEST PEG1 ENSG00000106484 "Mesoderm specific transcript" Q5EB52 7 130486171-130506465 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "placenta: 724.6" "Group enriched" "Detected in many" 4 "Adipocytes: 277.8;Cytotrophoblasts: 1091.7;Migrating cytotrophoblasts: 727.0;Syncytiotrophoblasts: 1027.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 656.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD8 T-cell: 24.2" "Group enriched" "Detected in all" 4 "dendritic cells: 9.2;granulocytes: 19.4;T-cells: 24.2" "Cancer enhanced" "Detected in all" "Rhabdoid: 745.8;Uterine cancer: 608.1" "Breast - Adipocytes (Breast), Skeletal muscle - Fibroblasts, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Spleen - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005623 Approved "Golgi apparatus,Cytosol" "Intracellular and membrane" Enzyme NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 108: Fibroblasts - ECM organization" 6 "Golgi apparatus, Cytosol" "HPA005623: " "unprognostic (2.31e-2)" "unprognostic (2.99e-1)" "unprognostic (3.33e-1)" "potential prognostic unfavorable (8.55e-4)" "unprognostic (2.68e-1)" "unprognostic (1.01e-1)" "unprognostic (8.09e-2)" "unprognostic (7.54e-3)" "unprognostic (1.38e-1)" "unprognostic (1.42e-1)" "unprognostic (4.56e-3)" "unprognostic (3.92e-2)" "unprognostic (1.28e-1)" "unprognostic (1.63e-2)" "unprognostic (3.05e-3)" "unprognostic (1.54e-2)" "unprognostic (8.20e-3)" "unprognostic (1.85e-1)" "unprognostic (5.85e-2)" "unprognostic (1.01e-1)" "unprognostic (3.07e-2)" "unprognostic (9.01e-2)" "unprognostic (1.72e-1)" "unprognostic (7.52e-2)" "unprognostic (3.55e-2)" "unprognostic (3.06e-1)" "unprognostic (1.56e-1)" "unprognostic (6.91e-2)" "unprognostic (1.74e-1)" "unprognostic (2.29e-1)" "unprognostic (1.34e-1)" MET "DFNB97, HGFR, RCCP2" ENSG00000105976 "MET proto-oncogene, receptor tyrosine kinase" P08581 7 116672196-116798377 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins, Transporters" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Deafness, Disease variant, FDA approved drug targets, Non-syndromic deafness, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 40.1" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 1017.9;Endometrial luminal cells: 524.5;Endometrial secretory cells: 439.5;Epididymal basal cells: 347.1;Ocular epithelial cells: 365.6;Retinal pigment epithelial cells: 349.6;Salivary basal cells: 520.8;Transitional alveolar cells: 417.5" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 64.5;hippocampal CA1-3: 48.0;oligodendrocyte: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 289.3" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Testis - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB005282, HPA055607" Approved Approved "Plasma membrane,Cytosol" "Secreted to blood" Receptor NA NA 179000000 28000000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 53: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 51: Secretory epithelial cells - Mixed function" 77 "Plasma membrane" Cytosol "CAB005282: , HPA055607: " "unprognostic (1.50e-1)" "unprognostic (3.09e-2)" "unprognostic (2.80e-1)" "unprognostic (1.67e-2)" "unprognostic (5.15e-2)" "unprognostic (2.01e-1)" "unprognostic (6.21e-3)" "unprognostic (8.75e-2)" "potential prognostic unfavorable (2.97e-4)" "unprognostic (2.45e-2)" "unprognostic (7.22e-3)" "unprognostic (1.55e-2)" "unprognostic (1.84e-1)" "unprognostic (2.86e-1)" "unprognostic (2.01e-2)" "unprognostic (3.73e-2)" "unprognostic (7.01e-3)" "unprognostic (2.15e-1)" "unprognostic (2.16e-1)" "unprognostic (2.13e-2)" "unprognostic (1.05e-2)" "potential prognostic unfavorable (6.80e-6)" "unprognostic (3.17e-3)" "unprognostic (1.41e-1)" "unprognostic (1.96e-2)" "unprognostic (5.90e-3)" "unprognostic (9.20e-2)" "unprognostic (8.35e-2)" "unprognostic (5.32e-2)" "unprognostic (3.05e-2)" "unprognostic (9.39e-2)" METAP1 "KIAA0094, MAP1A, MetAP1A" ENSG00000164024 "Methionyl aminopeptidase 1" P53582 4 98995659-99062809 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 7 "Late spermatids: 3047.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast myoepithelial cells, Skin - Mitotic cells (Skin), Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025485, HPA037997, HPA037998" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 43000 "Cluster 33: Non-specific - ATP binding" "Cluster 39: Testis - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 10 Cytosol "Nucleoplasm, Plasma membrane" "CAB025485: , HPA037997: , HPA037998: " "unprognostic (9.43e-2)" "unprognostic (6.37e-2)" "unprognostic (3.12e-2)" "unprognostic (8.72e-2)" "unprognostic (2.23e-2)" "unprognostic (1.09e-1)" "unprognostic (1.93e-1)" "unprognostic (1.39e-1)" "unprognostic (2.08e-1)" "unprognostic (3.59e-2)" "potential prognostic favorable (1.65e-7)" "unprognostic (5.12e-3)" "unprognostic (9.74e-2)" "potential prognostic unfavorable (9.69e-8)" "unprognostic (3.24e-2)" "potential prognostic unfavorable (9.25e-4)" "unprognostic (8.33e-3)" "unprognostic (3.02e-2)" "unprognostic (3.41e-1)" "unprognostic (6.49e-2)" "unprognostic (2.26e-1)" "potential prognostic unfavorable (3.18e-4)" "unprognostic (1.25e-1)" "unprognostic (2.13e-2)" "unprognostic (1.29e-3)" "unprognostic (8.06e-2)" "potential prognostic unfavorable (3.04e-5)" "unprognostic (4.77e-1)" "unprognostic (4.69e-2)" "unprognostic (1.29e-2)" "unprognostic (3.70e-2)" METAP1D "MAP1D, Metap1l" ENSG00000172878 "Methionyl aminopeptidase type 1D, mitochondrial" Q6UB28 2 171999943-172082430 "Enzymes, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Leydig cells: 89.1;Myonuclei: 108.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030298, HPA030299, HPA077742" Uncertain Uncertain Vesicles NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 24: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 94: Gonadal somatic cells - Mixed function" 3 Vesicles "HPA030298: , HPA030299: , HPA077742: " "unprognostic (1.63e-1)" "unprognostic (3.79e-2)" "unprognostic (4.21e-2)" "unprognostic (5.73e-3)" "unprognostic (8.19e-2)" "unprognostic (8.60e-2)" "unprognostic (5.09e-2)" "unprognostic (3.46e-3)" "unprognostic (1.13e-1)" "unprognostic (1.08e-1)" "unprognostic (1.23e-2)" "unprognostic (3.50e-2)" "unprognostic (1.56e-3)" "unprognostic (5.47e-2)" "potential prognostic unfavorable (6.01e-4)" "unprognostic (1.37e-1)" "unprognostic (7.55e-2)" "unprognostic (5.81e-3)" "unprognostic (1.40e-2)" "unprognostic (4.51e-2)" "unprognostic (3.97e-2)" "unprognostic (2.43e-2)" "unprognostic (6.79e-2)" "unprognostic (1.73e-3)" "unprognostic (2.14e-1)" "unprognostic (1.57e-1)" "unprognostic (1.10e-2)" "unprognostic (8.00e-2)" "unprognostic (1.31e-3)" "unprognostic (6.83e-2)" METAP2 "MAP2, MNPEP, p67" ENSG00000111142 "Methionyl aminopeptidase 2" P50579 12 95473520-95515839 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythrocyte progenitors: 730.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skin - Inner root sheath cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013025, HPA019095" Enhanced Supported "Plasma membrane,Cytosol" NA NA 35000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 142 "Plasma membrane, Cytosol" "CAB013025: , HPA019095: " "unprognostic (1.41e-1)" "unprognostic (3.21e-2)" "unprognostic (1.65e-2)" "unprognostic (3.64e-2)" "unprognostic (7.55e-2)" "unprognostic (9.89e-3)" "unprognostic (1.11e-1)" "unprognostic (2.37e-1)" "unprognostic (1.15e-2)" "potential prognostic unfavorable (4.58e-4)" "potential prognostic favorable (1.94e-6)" "unprognostic (2.11e-2)" "unprognostic (7.41e-3)" "potential prognostic unfavorable (2.73e-4)" "unprognostic (6.39e-3)" "unprognostic (3.11e-2)" "unprognostic (4.21e-2)" "unprognostic (3.55e-1)" "unprognostic (5.46e-2)" "unprognostic (2.57e-1)" "unprognostic (8.27e-3)" "unprognostic (8.16e-2)" "unprognostic (3.58e-2)" "unprognostic (3.33e-2)" "unprognostic (9.69e-2)" "unprognostic (5.90e-2)" "unprognostic (9.06e-2)" "unprognostic (1.05e-1)" "unprognostic (1.64e-1)" "unprognostic (8.71e-2)" "unprognostic (1.46e-1)" METRN "C16orf23, MGC2601" ENSG00000103260 "Meteorin, glial cell differentiation regulator" Q9UJH8 16 715118-719655 "Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 390.2;choroid plexus: 174.4" "Cell type enhanced" "Detected in many" "Bergmann glia: 317.8;Endometrial ciliated cells: 237.7;Ependymal cells: 451.0;Epididymal efferent duct ciliated cells: 310.6;Fallopian tube ciliated cells: 690.0;Müller glia: 595.1;Pituicytes/FSCs: 201.9;Respiratory ciliated cells: 345.7;Schwann cells: 233.7" "Cell type enhanced" "Detected in all" "Bergmann glia: 446.0;ependymal cell: 570.9" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 377.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Undifferentiated cells (Pituitary gland)" "Region enhanced" "Detected in all" "cerebellum: 612.7" "Low region specificity" "Detected in some" HPA051164 Approved Approved "Nucleoplasm,Nuclear membrane,Cytosol" "Secreted in brain" "Developmental protein" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 39: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 11: Muller glia cells - Retinal homeostasis" 25 "Nuclear membrane" "Nucleoplasm, Cytosol" "HPA051164: " "unprognostic (1.17e-2)" "unprognostic (1.29e-2)" "unprognostic (2.76e-1)" "unprognostic (1.20e-1)" "unprognostic (8.41e-2)" "unprognostic (3.89e-1)" "unprognostic (1.71e-2)" "unprognostic (4.21e-1)" "unprognostic (1.32e-1)" "unprognostic (3.10e-1)" "unprognostic (1.30e-1)" "unprognostic (3.50e-1)" "unprognostic (6.01e-2)" "unprognostic (2.31e-1)" "unprognostic (6.86e-2)" "unprognostic (1.55e-1)" "unprognostic (2.37e-1)" "unprognostic (1.30e-1)" "unprognostic (3.21e-1)" "unprognostic (1.11e-1)" "unprognostic (1.18e-1)" "unprognostic (4.15e-2)" "unprognostic (9.83e-2)" "unprognostic (1.38e-1)" "unprognostic (4.28e-2)" "unprognostic (1.23e-1)" "unprognostic (2.75e-1)" "unprognostic (1.99e-2)" "unprognostic (2.78e-1)" "unprognostic (2.11e-1)" "unprognostic (2.50e-1)" METRNL ENSG00000176845 "Meteorin like, glial cell differentiation regulator" Q641Q3 17 83079609-83095122 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 248.2" "Cell type enhanced" "Detected in many" "Bergmann glia: 26.5;Choroid plexus epithelial cells: 16.1;Ependymal cells: 15.8;Loop of henle epithelial cells: 13.5;monocytes: 15.9;Neutrophils: 14.6;NK-cells: 29.0;Papillary tip epithelial cells: 15.7;Renal collecting duct intercalated cells: 22.3;Renal collecting duct principal cells: 21.8;Renal connecting tubule cells: 22.5" "Cell type enhanced" "Detected in many" "Bergmann glia: 29.0;leukocyte: 61.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023792 Uncertain "Secreted to blood" Hormone NA NA 445000 490000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 58: Skin - Keratinization" "Cluster 12: Non-specific - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 33 "HPA023792: " "unprognostic (2.07e-2)" "unprognostic (1.25e-1)" "unprognostic (4.30e-2)" "unprognostic (1.04e-1)" "unprognostic (1.96e-1)" "unprognostic (1.83e-1)" "unprognostic (1.96e-1)" "unprognostic (5.87e-2)" "unprognostic (3.53e-1)" "unprognostic (4.26e-2)" "unprognostic (2.31e-3)" "unprognostic (3.05e-1)" "unprognostic (2.86e-2)" "unprognostic (1.26e-2)" "unprognostic (9.32e-2)" "unprognostic (1.44e-1)" "unprognostic (3.14e-3)" "unprognostic (6.17e-3)" "unprognostic (2.84e-1)" "unprognostic (2.99e-1)" "unprognostic (1.15e-1)" "unprognostic (1.45e-1)" "unprognostic (2.99e-2)" "unprognostic (8.01e-2)" "unprognostic (7.57e-2)" "unprognostic (5.15e-1)" "unprognostic (1.71e-1)" "unprognostic (4.20e-1)" "unprognostic (9.68e-2)" "unprognostic (5.98e-2)" "unprognostic (2.44e-1)" METTL1 "C12orf1, TRM8, TRMT8" ENSG00000037897 "Methyltransferase 1, tRNA methylguanosine" Q9UBP6 12 57768471-57772119 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, RNA-binding, Transferase, tRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 11.1;Early spermatids: 11.1;Late spermatids: 12.7" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020914, HPA050450" Uncertain Supported Nucleoplasm NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 70: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 38: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 5 Nucleoplasm "HPA020914: , HPA050450: " "unprognostic (7.41e-2)" "unprognostic (1.08e-1)" "unprognostic (1.37e-1)" "unprognostic (7.63e-2)" "unprognostic (1.81e-1)" "unprognostic (1.67e-1)" "unprognostic (5.16e-2)" "unprognostic (9.93e-2)" "unprognostic (2.71e-2)" "unprognostic (1.46e-1)" "validated prognostic unfavorable (2.24e-5)" "validated prognostic unfavorable (4.25e-7)" "unprognostic (2.44e-1)" "potential prognostic unfavorable (1.23e-7)" "unprognostic (2.93e-3)" "unprognostic (1.23e-2)" "potential prognostic unfavorable (2.33e-4)" "unprognostic (3.16e-2)" "unprognostic (1.93e-1)" "unprognostic (8.53e-3)" "unprognostic (4.08e-1)" "unprognostic (5.23e-2)" "unprognostic (1.59e-1)" "unprognostic (1.25e-1)" "unprognostic (4.71e-2)" "unprognostic (7.19e-3)" "unprognostic (1.90e-2)" "unprognostic (3.25e-1)" "unprognostic (1.95e-1)" "potential prognostic unfavorable (4.80e-4)" "unprognostic (1.19e-1)" METTL13 "CGI-01, DFNM1, EEF1AKNMT, FEAT, KIAA0859, METTL13" ENSG00000010165 "Methyltransferase 13, eEF1A lysine and N-terminal methyltransferase" Q8N6R0 1 171781660-171814023 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Methyltransferase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 44.4;Erythrocyte progenitors: 54.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025057, HPA044498, HPA053705" Approved Enhanced Cytosol NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 8 Cytosol "HPA025057: , HPA044498: , HPA053705: " "unprognostic (1.23e-1)" "unprognostic (1.09e-2)" "unprognostic (2.90e-2)" "unprognostic (7.48e-3)" "unprognostic (4.16e-2)" "unprognostic (5.08e-1)" "potential prognostic favorable (1.06e-6)" "unprognostic (2.13e-1)" "unprognostic (1.18e-1)" "potential prognostic favorable (4.06e-5)" "unprognostic (2.06e-1)" "unprognostic (2.18e-1)" "unprognostic (2.84e-3)" "unprognostic (5.00e-2)" "unprognostic (3.17e-2)" "unprognostic (6.97e-2)" "unprognostic (1.47e-1)" "unprognostic (4.60e-2)" "unprognostic (7.57e-2)" "unprognostic (1.39e-1)" "unprognostic (4.36e-2)" "unprognostic (2.93e-1)" "unprognostic (2.20e-2)" "unprognostic (9.81e-2)" "unprognostic (1.74e-1)" "unprognostic (7.47e-2)" "unprognostic (1.88e-1)" "unprognostic (1.76e-1)" "unprognostic (5.95e-2)" METTL14 KIAA1627 ENSG00000145388 "Methyltransferase 14, N6-adenosine-methyltransferase subunit" Q9HCE5 4 118685392-118715433 "Cancer-related genes, Essential proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 134.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038002 Supported Supported Nucleoplasm Yes No "Cluster 42: Non-specific - Vesicular transport" "Cluster 47: Testis - Mixed function" "Cluster 55: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 7: Non-specific - Transcription" 33 Nucleoplasm "HPA038002: " "unprognostic (2.17e-1)" "unprognostic (1.33e-1)" "unprognostic (3.67e-1)" "unprognostic (3.30e-3)" "unprognostic (3.51e-2)" "unprognostic (2.32e-1)" "unprognostic (1.99e-1)" "unprognostic (3.11e-1)" "unprognostic (3.09e-1)" "unprognostic (5.89e-3)" "validated prognostic favorable (6.57e-8)" "validated prognostic favorable (8.70e-5)" "unprognostic (1.46e-1)" "unprognostic (1.16e-1)" "unprognostic (7.94e-2)" "unprognostic (5.04e-2)" "unprognostic (6.07e-2)" "unprognostic (2.17e-1)" "unprognostic (1.23e-1)" "unprognostic (3.61e-2)" "unprognostic (8.30e-3)" "unprognostic (1.03e-1)" "unprognostic (1.67e-2)" "unprognostic (1.41e-2)" "unprognostic (2.10e-3)" "unprognostic (2.12e-1)" "unprognostic (6.10e-2)" "unprognostic (1.39e-1)" "unprognostic (1.80e-1)" "unprognostic (4.92e-2)" "unprognostic (4.93e-2)" METTL15 "FLJ33979, METT5D1" ENSG00000169519 "Methyltransferase like 15" A6NJ78 11 28108248-28527041 "Essential proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 9: Non-specific - Receptor signaling" "Cluster 24: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 43 "unprognostic (5.91e-2)" "unprognostic (1.95e-1)" "unprognostic (1.19e-2)" "unprognostic (3.19e-1)" "unprognostic (5.11e-2)" "unprognostic (7.07e-2)" "unprognostic (3.10e-1)" "unprognostic (2.07e-1)" "unprognostic (2.25e-2)" "potential prognostic favorable (5.19e-7)" "unprognostic (1.26e-3)" "unprognostic (2.11e-3)" "unprognostic (1.56e-3)" "unprognostic (2.69e-1)" "unprognostic (4.17e-2)" "unprognostic (2.13e-2)" "unprognostic (3.76e-1)" "unprognostic (6.01e-2)" "unprognostic (1.33e-1)" "potential prognostic unfavorable (2.42e-4)" "unprognostic (1.19e-3)" "unprognostic (6.68e-3)" "unprognostic (9.86e-2)" "unprognostic (1.79e-2)" "unprognostic (5.19e-2)" "unprognostic (1.12e-1)" "unprognostic (1.77e-1)" "unprognostic (2.12e-1)" "unprognostic (2.12e-1)" "unprognostic (3.20e-2)" METTL16 "METT10D, MGC3329" ENSG00000127804 "Methyltransferase 16, N6-methyladenosine" Q86W50 17 2405562-2511891 "Enzymes, Essential proteins, Predicted intracellular proteins" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020352, HPA059798" Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 3 Nucleoplasm Cytosol "HPA020352: , HPA059798: " "unprognostic (4.53e-2)" "unprognostic (4.42e-3)" "unprognostic (7.32e-3)" "unprognostic (4.14e-2)" "unprognostic (1.42e-1)" "unprognostic (1.27e-1)" "unprognostic (1.72e-2)" "unprognostic (1.74e-2)" "unprognostic (6.95e-2)" "validated prognostic favorable (2.80e-6)" "validated prognostic favorable (8.24e-7)" "unprognostic (2.60e-1)" "unprognostic (1.52e-1)" "unprognostic (2.83e-1)" "unprognostic (5.54e-2)" "unprognostic (9.75e-2)" "unprognostic (5.44e-3)" "unprognostic (5.24e-2)" "unprognostic (6.64e-2)" "unprognostic (1.66e-1)" "unprognostic (9.57e-2)" "unprognostic (7.03e-3)" "unprognostic (6.47e-2)" "unprognostic (6.80e-3)" "unprognostic (1.60e-2)" "unprognostic (2.36e-1)" "unprognostic (2.15e-1)" "unprognostic (1.86e-1)" "unprognostic (4.17e-2)" "unprognostic (9.66e-2)" METTL17 "FLJ20859, METT11D1" ENSG00000165792 "Methyltransferase like 17" Q9H7H0 14 20989973-20997035 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 107.2;Ocular epithelial cells: 108.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002955, HPA059802" Uncertain Enhanced Nucleoplasm No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 100: Stratified epithelial cells - Barrier functions" 50 Nucleoplasm "HPA002955: , HPA059802: " "unprognostic (2.10e-1)" "unprognostic (6.86e-2)" "unprognostic (7.84e-2)" "unprognostic (6.25e-3)" "unprognostic (1.82e-2)" "unprognostic (7.65e-2)" "potential prognostic favorable (5.72e-4)" "unprognostic (1.85e-2)" "unprognostic (3.86e-2)" "unprognostic (1.11e-3)" "unprognostic (3.33e-2)" "potential prognostic favorable (3.90e-4)" "unprognostic (3.18e-3)" "unprognostic (2.56e-2)" "unprognostic (1.32e-1)" "unprognostic (1.77e-1)" "unprognostic (3.27e-1)" "unprognostic (9.98e-2)" "unprognostic (1.50e-1)" "unprognostic (1.83e-2)" "unprognostic (2.94e-1)" "unprognostic (2.16e-2)" "unprognostic (1.05e-1)" "unprognostic (2.45e-1)" "unprognostic (4.67e-2)" "unprognostic (2.32e-1)" "unprognostic (5.51e-2)" "unprognostic (1.13e-1)" "unprognostic (1.17e-1)" "potential prognostic favorable (8.76e-4)" METTL18 "AsTP2, C1orf156, HPM1, MGC9084" ENSG00000171806 "Methyltransferase like 18" O95568 1 169792529-169794963 "Enzymes, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 22.4;Oocytes: 32.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035314 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 55: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" 10 Nucleoplasm Cytosol "HPA035314: " "unprognostic (8.47e-2)" "unprognostic (1.15e-1)" "unprognostic (3.50e-1)" "unprognostic (9.47e-2)" "unprognostic (6.80e-2)" "unprognostic (1.94e-1)" "unprognostic (1.30e-1)" "unprognostic (1.75e-1)" "potential prognostic unfavorable (2.17e-4)" "unprognostic (2.41e-3)" "unprognostic (2.86e-3)" "unprognostic (8.83e-2)" "potential prognostic unfavorable (2.67e-4)" "unprognostic (3.96e-2)" "unprognostic (3.98e-2)" "unprognostic (2.88e-2)" "unprognostic (4.17e-1)" "unprognostic (2.16e-1)" "unprognostic (1.34e-1)" "unprognostic (2.97e-2)" "unprognostic (1.19e-1)" "unprognostic (2.51e-1)" "unprognostic (2.29e-2)" "unprognostic (1.87e-1)" "unprognostic (1.75e-2)" "unprognostic (1.10e-2)" "unprognostic (1.89e-1)" "unprognostic (6.29e-3)" "unprognostic (2.61e-1)" "unprognostic (1.42e-1)" METTL21A "FAM119A, HCA557b, HSPA-KMT, LOC151194" ENSG00000144401 "Methyltransferase 21A, HSPA lysine" Q8WXB1 2 207580631-207625928 "Predicted intracellular proteins, Predicted membrane proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 156.9;Mast cells: 126.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034712 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 31 Nucleoplasm Cytosol "HPA034712: " "unprognostic (5.24e-2)" "unprognostic (1.13e-1)" "unprognostic (2.23e-1)" "unprognostic (1.30e-2)" "unprognostic (1.59e-2)" "unprognostic (7.02e-2)" "unprognostic (7.40e-2)" "unprognostic (5.27e-2)" "unprognostic (3.04e-2)" "unprognostic (2.67e-2)" "unprognostic (1.48e-2)" "unprognostic (3.45e-2)" "unprognostic (6.53e-2)" "unprognostic (2.51e-1)" "unprognostic (1.08e-1)" "unprognostic (2.64e-2)" "unprognostic (3.72e-2)" "unprognostic (1.36e-2)" "unprognostic (4.10e-2)" "unprognostic (4.63e-3)" "unprognostic (3.80e-1)" "unprognostic (2.11e-3)" "unprognostic (4.99e-2)" "unprognostic (1.63e-2)" "unprognostic (1.65e-3)" "unprognostic (4.93e-2)" "unprognostic (4.31e-2)" "unprognostic (1.99e-1)" "unprognostic (2.74e-1)" "unprognostic (1.86e-1)" METTL21C "C13orf39, LOC196541" ENSG00000139780 "Methyltransferase 21C, AARS1 lysine" Q5VZV1 13 102685747-102695044 "Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "epididymis: 23.4" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 4.8;Early spermatids: 3.3;Epididymal principal cells: 27.7;Late spermatids: 7.8;Myonuclei: 6.8;Retinal ganglion cells: 7.7;Syncytiotrophoblasts: 2.1" "Cell type enhanced" "Detected in some" "upper rhombic lip: 1.3;upper-layer intratelencephalic: 1.4" "Cancer enriched" "Detected in single" 5 "Kidney Chromophobe (TCGA): 1.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 5: Rhabdoid - Unknown function" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" 3 "unprognostic (9.19e-2)" METTL22 "C16orf68, FLJ12433,MGC2654" ENSG00000067365 "Methyltransferase 22, Kin17 lysine" Q9BUU2 16 8621683-8649654 "Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Late spermatids: 641.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 9.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040803, HPA059882, HPA074173" Uncertain Supported "Nucleoplasm,Nucleoli rim" Yes No "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 67: Testis - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 54: Non-specific - Transcription" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 3 "Nucleoli rim" Nucleoplasm "HPA040803: , HPA059882: , HPA074173: " "unprognostic (2.35e-1)" "unprognostic (2.52e-1)" "unprognostic (3.94e-3)" "unprognostic (1.38e-1)" "unprognostic (4.34e-2)" "unprognostic (1.19e-1)" "unprognostic (4.98e-3)" "unprognostic (9.89e-2)" "unprognostic (1.58e-3)" "potential prognostic unfavorable (6.11e-6)" "unprognostic (1.90e-2)" "unprognostic (2.65e-2)" "unprognostic (3.79e-2)" "unprognostic (6.87e-2)" "unprognostic (2.90e-1)" "unprognostic (7.62e-2)" "unprognostic (2.12e-1)" "unprognostic (1.58e-2)" "unprognostic (5.26e-2)" "unprognostic (2.58e-1)" "potential prognostic favorable (7.99e-4)" "potential prognostic unfavorable (6.97e-4)" "unprognostic (1.61e-1)" "unprognostic (7.51e-2)" "unprognostic (1.80e-2)" "unprognostic (1.04e-1)" "unprognostic (3.47e-3)" "unprognostic (2.81e-1)" "unprognostic (3.70e-2)" "unprognostic (1.37e-2)" METTL23 "C17orf95, LOC124512" ENSG00000181038 "Methyltransferase like 23" Q86XA0 17 76726830-76733936 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Chromatin regulator, Developmental protein, Methyltransferase, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 77.8;Late primary spermatocytes: 203.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022889 Approved Vesicles No No "Cluster 3: Non-specific - Nuclear processes" "Cluster 70: Non-specific - Protein processing" "Cluster 55: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 1 Vesicles "HPA022889: " "unprognostic (9.50e-2)" "unprognostic (2.61e-1)" "unprognostic (2.07e-1)" "unprognostic (3.08e-1)" "unprognostic (1.08e-1)" "unprognostic (1.73e-2)" "unprognostic (1.45e-1)" "unprognostic (5.02e-2)" "unprognostic (6.26e-2)" "unprognostic (1.63e-2)" "unprognostic (3.45e-2)" "unprognostic (1.31e-1)" "validated prognostic unfavorable (5.32e-6)" "validated prognostic unfavorable (3.67e-4)" "unprognostic (1.87e-2)" "unprognostic (3.13e-2)" "unprognostic (5.62e-2)" "unprognostic (1.52e-1)" "unprognostic (1.66e-1)" "unprognostic (1.24e-1)" "unprognostic (1.84e-2)" "unprognostic (1.52e-1)" "unprognostic (8.05e-2)" "unprognostic (5.43e-3)" "unprognostic (8.86e-2)" "unprognostic (1.29e-1)" "unprognostic (1.21e-2)" "unprognostic (1.90e-1)" "unprognostic (1.50e-1)" "unprognostic (2.92e-2)" METTL24 "C6orf186, dJ71D21.2" ENSG00000053328 "Methyltransferase like 24" Q5JXM2 6 110243940-110358349 "Predicted secreted proteins" "Methyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 189.1;Gonadotrophs: 82.0;Lactotrophs: 66.5;Oligodendrocyte progenitor cells: 52.0;Pituicytes/FSCs: 58.4;Pituitary stem cells: 182.9;Podocytes: 80.3;Retinal horizontal cells: 70.1;Thyrotrophs: 57.4" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 159.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "MAIT T-cell: 2.4" "Lineage enriched" "Detected in single" 11 "T-cells: 2.4" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Fibroblasts, Colon - Smooth muscle cells, Liver - Hepatic stellate cells, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Testis - Early spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA037441, HPA037442" Uncertain "Secreted - unknown location" Enzyme NA NA "Cluster 24: Non-specific - Transcription" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 101: Choroid plexus epithelial cells - Ion transport" "HPA037441: , HPA037442: " "unprognostic (1.75e-1)" "unprognostic (5.68e-3)" "validated prognostic favorable (1.43e-9)" "validated prognostic favorable (4.75e-5)" "unprognostic (2.38e-2)" "unprognostic (1.83e-1)" "unprognostic (1.41e-2)" "unprognostic (2.32e-1)" "unprognostic (3.37e-2)" "unprognostic (1.52e-2)" "unprognostic (1.15e-1)" "unprognostic (1.47e-1)" "unprognostic (7.51e-2)" "unprognostic (4.47e-2)" "unprognostic (1.47e-2)" "unprognostic (3.78e-1)" METTL25 "C12orf26, FLJ22789" ENSG00000127720 "Methyltransferase like 25" Q8N6Q8 12 82358528-82479239 "Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Corticotrophs: 201.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039534, HPA041207" Enhanced Uncertain "Plasma membrane,Mitochondria,Cytosol" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 2 "Plasma membrane, Mitochondria, Cytosol" "HPA039534: , HPA041207: " "unprognostic (4.38e-3)" "unprognostic (1.41e-1)" "unprognostic (7.23e-3)" "unprognostic (2.76e-2)" "unprognostic (4.03e-2)" "unprognostic (1.30e-1)" "unprognostic (1.76e-1)" "unprognostic (4.70e-2)" "potential prognostic unfavorable (7.16e-5)" "potential prognostic favorable (7.90e-7)" "unprognostic (2.36e-3)" "unprognostic (1.79e-1)" "unprognostic (1.07e-2)" "unprognostic (1.80e-2)" "unprognostic (4.30e-2)" "unprognostic (2.98e-2)" "unprognostic (2.68e-2)" "unprognostic (1.60e-1)" "potential prognostic unfavorable (1.27e-4)" "unprognostic (1.71e-1)" "unprognostic (1.76e-1)" "unprognostic (5.94e-2)" "unprognostic (1.62e-1)" "potential prognostic favorable (7.77e-4)" "unprognostic (1.49e-1)" "unprognostic (8.16e-3)" "unprognostic (3.10e-2)" "unprognostic (2.54e-1)" "unprognostic (1.70e-1)" METTL25B "C1orf66, CGI-41, RRNAD1" ENSG00000143303 "Methyltransferase like 25B" Q96FB5 1 156728442-156736960 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 128.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047426 Approved Approved Nucleoli,Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 54: Non-specific - Ribosome" "Cluster 6: Non-specific - Immune response" "Cluster 45: Non-specific - Nuclear processes" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" Nucleoli Cytosol "HPA047426: " "unprognostic (8.60e-2)" "unprognostic (1.24e-1)" "unprognostic (4.39e-3)" "unprognostic (5.02e-3)" "unprognostic (2.36e-1)" "unprognostic (1.44e-1)" "potential prognostic favorable (2.33e-5)" "unprognostic (2.93e-1)" "unprognostic (3.39e-2)" "unprognostic (5.13e-2)" "unprognostic (7.09e-2)" "unprognostic (1.92e-1)" "unprognostic (2.83e-2)" "unprognostic (1.22e-1)" "unprognostic (1.33e-1)" "unprognostic (2.25e-1)" "unprognostic (1.72e-1)" "unprognostic (2.30e-1)" "unprognostic (2.77e-1)" "unprognostic (7.33e-2)" "unprognostic (1.71e-1)" "unprognostic (1.07e-1)" "unprognostic (1.48e-1)" "unprognostic (1.71e-1)" "unprognostic (2.08e-1)" "unprognostic (4.23e-3)" "unprognostic (1.33e-1)" "unprognostic (9.69e-3)" "unprognostic (2.48e-1)" "unprognostic (1.41e-2)" METTL26 "C16orf13, MGC13114" ENSG00000130731 "Methyltransferase like 26" Q96S19 16 634427-636366 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 776.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044004, HPA067414" Uncertain Approved "Golgi apparatus" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 33: Neurons - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" "Golgi apparatus" "HPA044004: , HPA067414: " "unprognostic (7.56e-3)" "unprognostic (1.27e-1)" "unprognostic (3.09e-2)" "unprognostic (1.02e-1)" "unprognostic (1.60e-1)" "unprognostic (2.76e-1)" "unprognostic (1.44e-1)" "unprognostic (4.68e-2)" "unprognostic (3.85e-2)" "unprognostic (3.88e-2)" "unprognostic (1.16e-1)" "unprognostic (2.46e-2)" "unprognostic (1.75e-2)" "unprognostic (1.13e-1)" "unprognostic (1.71e-2)" "unprognostic (2.06e-1)" "unprognostic (6.10e-2)" "unprognostic (7.09e-2)" "unprognostic (1.24e-1)" "unprognostic (3.33e-2)" "unprognostic (3.98e-1)" "unprognostic (5.84e-2)" "unprognostic (2.95e-1)" "unprognostic (2.59e-1)" "unprognostic (3.78e-1)" "unprognostic (1.98e-1)" "unprognostic (3.03e-2)" "unprognostic (2.46e-1)" "unprognostic (1.17e-1)" METTL27 WBSCR27 ENSG00000165171 "Methyltransferase like 27" Q8N6F8 7 73834590-73842516 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 19.1" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 63.9;Enterocytes: 44.3;Epididymal efferent duct ciliated cells: 102.0;Fallopian tube ciliated cells: 75.7;Gastric progenitor cells: 44.9;Megakaryocytes: 49.5;Respiratory ciliated cells: 89.0" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 12.1;ependymal cell: 20.4" "Cancer enriched" "Detected in all" 4 "Kidney Renal Papillary Cell Carcinoma (TCGA): 64.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 6.4" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA074662 Approved Approved Mitochondria,Cytosol NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 107: Ciliated cells - Cilia assembly & function" 43 "Mitochondria, Cytosol" "HPA074662: " "unprognostic (5.99e-3)" "unprognostic (1.28e-1)" "unprognostic (9.43e-2)" "unprognostic (3.65e-3)" "unprognostic (2.03e-1)" "unprognostic (4.98e-3)" "unprognostic (1.93e-2)" "unprognostic (1.80e-2)" "unprognostic (1.09e-1)" "validated prognostic favorable (2.17e-7)" "validated prognostic favorable (4.36e-5)" "potential prognostic favorable (3.64e-5)" "unprognostic (3.44e-3)" "unprognostic (1.60e-1)" "unprognostic (1.47e-3)" "unprognostic (9.58e-2)" "unprognostic (2.48e-1)" "unprognostic (2.10e-1)" "unprognostic (1.64e-1)" "unprognostic (5.47e-2)" "unprognostic (1.89e-1)" "unprognostic (1.57e-1)" "unprognostic (2.74e-1)" "unprognostic (1.23e-1)" "unprognostic (1.59e-1)" "unprognostic (8.89e-2)" "unprognostic (2.46e-2)" "unprognostic (4.66e-2)" "unprognostic (2.69e-2)" METTL2A "FLJ12760, METTL2" ENSG00000087995 "Methyltransferase 2A, methylcytidine" Q96IZ6 17 62423875-62453385 "Plasma proteins, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach)" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 27: Breast cancer - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 1 "unprognostic (5.20e-2)" "unprognostic (1.28e-3)" "unprognostic (1.20e-1)" "unprognostic (5.61e-2)" "unprognostic (1.89e-1)" "unprognostic (1.77e-2)" "unprognostic (4.68e-2)" "unprognostic (4.56e-1)" "unprognostic (5.52e-2)" "unprognostic (3.10e-3)" "unprognostic (1.90e-1)" "unprognostic (4.41e-2)" "unprognostic (3.76e-2)" "unprognostic (2.87e-3)" "potential prognostic unfavorable (6.12e-6)" "unprognostic (1.92e-1)" "unprognostic (2.14e-1)" "unprognostic (1.86e-1)" "unprognostic (1.83e-2)" "unprognostic (1.30e-1)" "unprognostic (2.86e-1)" "potential prognostic favorable (6.05e-5)" "unprognostic (3.23e-2)" "unprognostic (4.41e-3)" "potential prognostic favorable (3.69e-4)" "unprognostic (2.17e-2)" "unprognostic (1.61e-1)" "unprognostic (1.79e-2)" "unprognostic (8.01e-2)" "unprognostic (4.30e-3)" "unprognostic (1.21e-1)" METTL2B "FLJ11350, METL, METTL2" ENSG00000165055 "Methyltransferase 2B, methylcytidine" Q6P1Q9 7 128476729-128506602 "Predicted intracellular proteins, Predicted membrane proteins" "tRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 102: Non-specific - Mixed function" 1 "unprognostic (2.13e-2)" "unprognostic (8.37e-2)" "unprognostic (4.62e-2)" "unprognostic (1.28e-3)" "unprognostic (1.10e-1)" "unprognostic (1.54e-1)" "unprognostic (2.75e-1)" "unprognostic (5.72e-2)" "unprognostic (2.32e-2)" "potential prognostic unfavorable (4.26e-4)" "unprognostic (1.93e-2)" "unprognostic (2.63e-1)" "unprognostic (1.85e-3)" "unprognostic (1.56e-3)" "unprognostic (4.44e-3)" "unprognostic (1.11e-1)" "unprognostic (9.60e-3)" "unprognostic (2.28e-1)" "unprognostic (3.46e-3)" "unprognostic (1.85e-1)" "unprognostic (3.30e-1)" "unprognostic (9.02e-2)" "unprognostic (1.95e-3)" "unprognostic (5.83e-3)" "unprognostic (5.04e-2)" "unprognostic (8.98e-2)" "unprognostic (1.65e-3)" "unprognostic (6.68e-2)" "unprognostic (4.59e-2)" "potential prognostic unfavorable (1.55e-4)" "unprognostic (2.74e-1)" METTL3 "M6A, MT-A70, Spo8" ENSG00000165819 "Methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit" Q86U44 14 21498133-21511342 "Enzymes, Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Differentiation, DNA damage, Immunity, Innate immunity, Oogenesis, Spermatogenesis" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 176.7;Late primary spermatocytes: 177.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA079662 Supported "Nucleoplasm,Nuclear bodies,Golgi apparatus,Cytosol" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 22: Epididymis - Mixed function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 23 "Nucleoplasm, Cytosol" "Nuclear bodies, Golgi apparatus" "HPA079662: " "unprognostic (3.52e-3)" "unprognostic (2.28e-2)" "unprognostic (4.66e-1)" "unprognostic (2.77e-2)" "unprognostic (4.89e-2)" "unprognostic (3.79e-2)" "unprognostic (4.11e-1)" "potential prognostic favorable (1.04e-4)" "unprognostic (1.60e-2)" "unprognostic (1.47e-2)" "potential prognostic favorable (4.50e-4)" "unprognostic (1.22e-2)" "unprognostic (5.61e-2)" "potential prognostic unfavorable (8.46e-6)" "unprognostic (1.80e-3)" "unprognostic (1.70e-1)" "unprognostic (6.78e-3)" "unprognostic (1.37e-1)" "unprognostic (5.65e-2)" "unprognostic (7.69e-2)" "unprognostic (3.01e-1)" "unprognostic (1.61e-1)" "unprognostic (8.60e-2)" "unprognostic (1.11e-1)" "unprognostic (2.58e-1)" "unprognostic (2.19e-1)" "unprognostic (3.60e-1)" "unprognostic (1.10e-1)" "unprognostic (5.29e-2)" "unprognostic (5.57e-2)" "unprognostic (2.29e-3)" METTL4 "FLJ23017, HsT661" ENSG00000101574 "Methyltransferase 4, N6-adenosine" Q8N3J2 18 2537525-2571509 "Enzymes, Predicted intracellular proteins" "Chromatin regulator, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040061, HPA046734" Approved Approved Mitochondria NA Yes "Cluster 21: Neutrophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 7: Non-specific - Transcription" Mitochondria "HPA040061: , HPA046734: " "unprognostic (2.17e-1)" "unprognostic (9.34e-2)" "unprognostic (1.60e-1)" "unprognostic (5.98e-2)" "unprognostic (3.16e-1)" "unprognostic (1.62e-2)" "unprognostic (6.24e-2)" "unprognostic (1.61e-2)" "unprognostic (1.20e-3)" "potential prognostic unfavorable (6.99e-4)" "unprognostic (3.12e-2)" "potential prognostic favorable (4.74e-4)" "unprognostic (3.08e-1)" "potential prognostic unfavorable (5.91e-5)" "unprognostic (2.93e-2)" "unprognostic (1.54e-1)" "unprognostic (2.17e-3)" "unprognostic (1.23e-2)" "unprognostic (8.16e-2)" "unprognostic (2.45e-2)" "unprognostic (5.59e-2)" "unprognostic (3.79e-1)" "unprognostic (2.17e-2)" "unprognostic (2.16e-2)" "unprognostic (2.34e-1)" "unprognostic (2.65e-1)" "unprognostic (1.15e-1)" "unprognostic (1.24e-1)" "unprognostic (7.31e-2)" "unprognostic (5.36e-2)" "unprognostic (2.18e-2)" METTL5 HSPC133 ENSG00000138382 "Methyltransferase 5, N6-adenosine" Q9NRN9 2 169810081-169824931 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Methyltransferase, Transferase" "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038223 Uncertain Supported "Nucleoli,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 97: Non-specific - Cellular respiration" 2 "Nucleoli, Nucleoli fibrillar center" Cytosol "HPA038223: " "unprognostic (8.26e-2)" "potential prognostic unfavorable (4.17e-4)" "unprognostic (2.40e-1)" "unprognostic (1.24e-1)" "unprognostic (3.42e-2)" "unprognostic (1.97e-1)" "unprognostic (2.98e-1)" "unprognostic (2.71e-1)" "unprognostic (1.23e-3)" "unprognostic (3.26e-2)" "unprognostic (4.23e-2)" "unprognostic (8.14e-3)" "unprognostic (3.18e-3)" "validated prognostic unfavorable (3.27e-6)" "validated prognostic unfavorable (7.23e-6)" "potential prognostic unfavorable (8.57e-6)" "unprognostic (1.82e-2)" "unprognostic (9.91e-2)" "unprognostic (5.63e-2)" "unprognostic (8.16e-2)" "unprognostic (3.49e-2)" "potential prognostic unfavorable (4.03e-5)" "unprognostic (2.19e-1)" "unprognostic (7.41e-2)" "unprognostic (2.32e-1)" "unprognostic (2.00e-1)" "unprognostic (5.72e-2)" "unprognostic (1.86e-1)" "unprognostic (1.08e-1)" "unprognostic (7.60e-2)" "unprognostic (3.83e-1)" METTL6 MGC24132 ENSG00000206562 "Methyltransferase 6, methylcytidine" Q8TCB7 3 15381275-15440566 "Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 263.9;Epicardial cells: 136.4;Late primary spermatocytes: 178.7;Late spermatids: 160.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035166 Uncertain Approved Vesicles No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 65: Brain - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 7 Vesicles "HPA035166: " "unprognostic (9.42e-2)" "unprognostic (5.34e-2)" "unprognostic (4.25e-2)" "unprognostic (7.06e-3)" "unprognostic (3.86e-3)" "unprognostic (2.76e-1)" "unprognostic (1.11e-1)" "unprognostic (6.74e-3)" "unprognostic (1.20e-1)" "potential prognostic unfavorable (9.27e-6)" "unprognostic (1.42e-1)" "unprognostic (3.17e-1)" "unprognostic (3.06e-1)" "potential prognostic unfavorable (3.20e-7)" "unprognostic (1.02e-3)" "unprognostic (1.72e-2)" "unprognostic (2.23e-2)" "unprognostic (1.58e-1)" "unprognostic (6.60e-2)" "unprognostic (2.43e-1)" "unprognostic (2.34e-3)" "unprognostic (3.48e-1)" "unprognostic (8.04e-3)" "unprognostic (7.76e-2)" "potential prognostic favorable (1.43e-4)" "unprognostic (2.31e-2)" "unprognostic (7.55e-2)" "unprognostic (5.56e-3)" "unprognostic (1.83e-1)" "unprognostic (3.95e-3)" "unprognostic (6.58e-2)" METTL7A DKFZP586A0522 ENSG00000185432 "Methyltransferase like 7A" Q9H8H3 12 50923472-50932510 "Predicted membrane proteins" "Host-virus interaction" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 395.4" "Cell type enhanced" "Detected in many" "Astrocytes: 121.5;Bergmann glia: 107.5;Choroid plexus epithelial cells: 35.6;Ependymal cells: 131.3;Loop of henle epithelial cells: 45.1;Microglia: 106.2;Oligodendrocyte progenitor cells: 61.9;Papillary tip epithelial cells: 76.6;Proximal tubule cells: 72.0;Renal collecting duct intercalated cells: 37.1;Renal collecting duct principal cells: 39.1" "Cell type enhanced" "Detected in all" "ependymal cell: 157.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 94.8;classical monocyte: 34.9;eosinophil: 69.9;intermediate monocyte: 37.4;memory B-cell: 31.8;myeloid DC: 30.4;naive B-cell: 34.1;non-classical monocyte: 59.0;plasmacytoid DC: 25.0" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Myeloma: 88.0" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Spleen - Fibroblasts_2, Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA017434 Supported "Lipid droplets" NA NA 8700 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 98: Neurons - Neurotransmission & signaling" 17 "Lipid droplets" "HPA017434: " "unprognostic (1.40e-3)" "unprognostic (3.36e-2)" "unprognostic (3.75e-1)" "unprognostic (2.20e-1)" "unprognostic (4.84e-2)" "unprognostic (4.29e-2)" "unprognostic (9.04e-2)" "unprognostic (6.02e-2)" "unprognostic (1.91e-2)" "unprognostic (4.03e-2)" "validated prognostic favorable (1.16e-11)" "validated prognostic favorable (2.85e-5)" "potential prognostic favorable (5.67e-5)" "unprognostic (3.52e-3)" "unprognostic (2.37e-1)" "potential prognostic favorable (1.90e-4)" "unprognostic (4.32e-3)" "unprognostic (9.94e-2)" "unprognostic (1.70e-1)" "unprognostic (1.28e-1)" "unprognostic (2.66e-1)" "unprognostic (4.96e-2)" "unprognostic (1.38e-2)" "unprognostic (1.24e-1)" "unprognostic (6.08e-2)" "unprognostic (1.87e-1)" "unprognostic (2.49e-2)" "unprognostic (1.47e-1)" "unprognostic (1.76e-1)" "unprognostic (7.80e-2)" "unprognostic (8.17e-2)" METTL7B "ALDI, MGC17301" ENSG00000170439 "Methyltransferase like 7B" Q6UX53 12 55681736-55684611 "Enzymes, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 126.1;heart muscle: 136.0;liver: 267.4" "Cell type enhanced" "Detected in some" "Colonocytes: 33.8;Enteric transient amplifying cells: 30.9;Enterocytes: 181.6;Epididymal efferent duct absorptive cells: 86.2;Epididymal principal cells: 136.3;Hepatocytes: 93.1;Hofbauer cells: 166.6;Kupffer cells: 34.8;Pituicytes/FSCs: 37.2" "Cell type enhanced" "Detected in some" "hippocampal CA1-3: 5.0;hippocampal CA4: 11.0;hippocampal dentate gyrus: 12.2" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 181.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "intermediate monocyte: 4.5;myeloid DC: 7.0;naive B-cell: 1.7;non-classical monocyte: 3.3" "Group enriched" "Detected in many" 44 "B-cells: 1.7;dendritic cells: 7.0;monocytes: 4.5" "Cancer enhanced" "Detected in many" "colorectal cancer: 44.0" "Kidney - Proximal tubular cells, Skin - Sebaceous gland cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA038644 Enhanced Approved Vesicles,Microtubules NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 29: Forebrain - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" Microtubules Vesicles "HPA038644: " "unprognostic (7.50e-3)" "unprognostic (7.09e-2)" "unprognostic (1.97e-1)" "unprognostic (1.29e-1)" "unprognostic (1.48e-1)" "unprognostic (5.22e-2)" "unprognostic (4.46e-2)" "potential prognostic unfavorable (6.59e-4)" "potential prognostic unfavorable (4.27e-4)" "unprognostic (1.72e-1)" "unprognostic (1.60e-3)" "unprognostic (2.63e-1)" "unprognostic (5.92e-2)" "unprognostic (2.09e-1)" "unprognostic (3.07e-2)" "unprognostic (3.50e-1)" "unprognostic (5.31e-2)" "unprognostic (1.64e-2)" "unprognostic (1.22e-1)" "unprognostic (1.50e-1)" "unprognostic (1.77e-1)" "unprognostic (1.50e-2)" "unprognostic (2.33e-2)" "unprognostic (1.31e-1)" "unprognostic (1.84e-1)" "unprognostic (1.21e-1)" "unprognostic (4.22e-2)" "unprognostic (2.07e-1)" "potential prognostic favorable (4.84e-4)" "unprognostic (2.92e-2)" METTL8 "FLJ13984, TIP" ENSG00000123600 "Methyltransferase 8, methylcytidine" 2 171315746-171434802 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035421 Uncertain Approved Cytosol NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 9: Non-specific - Receptor signaling" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 17: Non-specific - RNA processing" Cytosol "HPA035421: " "unprognostic (2.59e-1)" "unprognostic (1.97e-1)" "unprognostic (6.57e-2)" "unprognostic (2.81e-2)" "unprognostic (1.18e-2)" "unprognostic (3.40e-2)" "unprognostic (1.04e-1)" "unprognostic (4.02e-1)" "unprognostic (4.02e-2)" "unprognostic (6.40e-2)" "unprognostic (1.50e-1)" "unprognostic (2.26e-1)" "unprognostic (2.03e-1)" "potential prognostic unfavorable (1.75e-4)" "unprognostic (8.03e-3)" "potential prognostic unfavorable (1.26e-4)" "unprognostic (4.53e-2)" "unprognostic (1.06e-1)" "unprognostic (3.61e-1)" "unprognostic (6.41e-2)" "unprognostic (1.24e-1)" "unprognostic (1.97e-3)" "unprognostic (1.64e-2)" "unprognostic (2.63e-1)" "unprognostic (1.05e-1)" "potential prognostic favorable (3.14e-4)" "unprognostic (1.13e-3)" "unprognostic (1.22e-1)" "unprognostic (2.92e-1)" "potential prognostic unfavorable (5.16e-4)" "unprognostic (2.52e-1)" METTL9 DREV1 ENSG00000197006 "Methyltransferase like 9" Q9H1A3 16 21597218-21657471 "Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 48.0;Choroid plexus epithelial cells: 70.9;Distal convoluted tubule cells: 51.5;Ependymal cells: 55.8;Loop of henle epithelial cells: 54.3;Microglia: 121.5;Neutrophils: 46.3;Papillary tip epithelial cells: 48.7;Proximal tubule cells: 107.3;Renal collecting duct intercalated cells: 43.1;Renal collecting duct principal cells: 58.4;Renal connecting tubule cells: 98.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053588, HPA056347" Uncertain Approved "Nucleoplasm,Cell Junctions,Cytosol" "Intracellular and membrane" Enzyme NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 72: Kidney - Transmembrane transport" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 102: Non-specific - Mixed function" 11 "Nucleoplasm, Cell Junctions" Cytosol "HPA053588: , HPA056347: " "unprognostic (1.16e-1)" "unprognostic (1.38e-2)" "unprognostic (5.07e-2)" "unprognostic (2.21e-1)" "unprognostic (8.59e-2)" "unprognostic (2.80e-1)" "unprognostic (2.14e-2)" "unprognostic (1.32e-1)" "unprognostic (3.39e-1)" "unprognostic (3.11e-2)" "potential prognostic favorable (2.25e-9)" "unprognostic (4.40e-2)" "unprognostic (2.64e-1)" "potential prognostic unfavorable (2.73e-4)" "unprognostic (1.17e-2)" "unprognostic (2.52e-3)" "unprognostic (1.15e-1)" "unprognostic (2.39e-1)" "unprognostic (3.21e-1)" "unprognostic (3.18e-2)" "unprognostic (8.24e-3)" "unprognostic (2.35e-2)" "unprognostic (4.10e-3)" "unprognostic (1.13e-1)" "unprognostic (2.14e-3)" "unprognostic (9.62e-2)" "unprognostic (9.85e-3)" "unprognostic (2.01e-2)" "unprognostic (5.55e-1)" "unprognostic (4.43e-2)" "unprognostic (3.11e-1)" MEX3A "RKHD4, RNF162" ENSG00000254726 "Mex-3 RNA binding family member A" A1L020 1 156072013-156082465 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "ovary: 5.6" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 13.8;Breast secretory cells: 29.7;Gastric progenitor cells: 11.5;Granulosa cells: 22.7;Respiratory ionocytes: 30.5" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 6.3;oligodendrocyte precursor cell: 6.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Neuroblastoma: 68.4" "Skin - Outer root sheath cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA062703 Supported Cytosol NA NA "Cluster 75: Ovary - Mixed function" "Cluster 25: Non-specific - Transcription" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 108: Fibroblasts - ECM organization" 6 Cytosol "HPA062703: " "unprognostic (1.09e-1)" "unprognostic (6.87e-2)" "unprognostic (1.16e-1)" "unprognostic (1.11e-1)" "unprognostic (3.22e-1)" "unprognostic (2.14e-2)" "unprognostic (2.72e-2)" "unprognostic (1.09e-2)" "unprognostic (5.70e-2)" "unprognostic (6.28e-2)" "unprognostic (3.32e-2)" "unprognostic (3.42e-2)" "potential prognostic unfavorable (7.80e-9)" "unprognostic (7.13e-2)" "unprognostic (1.14e-2)" "unprognostic (1.18e-2)" "unprognostic (2.42e-1)" "unprognostic (1.65e-2)" "unprognostic (5.35e-2)" "unprognostic (1.73e-1)" "unprognostic (5.06e-2)" "unprognostic (1.13e-2)" "unprognostic (1.01e-1)" "unprognostic (1.45e-1)" "unprognostic (1.99e-1)" "unprognostic (1.98e-2)" "unprognostic (4.14e-2)" "unprognostic (3.30e-2)" "unprognostic (5.45e-2)" "unprognostic (5.30e-2)" MEX3B "DKFZp434J0617, RKHD3, RNF195" ENSG00000183496 "Mex-3 RNA binding family member B" Q6ZN04 15 82041778-82046119 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "cervix: 12.4;testis: 45.1" "Group enriched" "Detected in many" 7 "Early spermatids: 264.0;Late spermatids: 304.0" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 20.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 24.4" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041093 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 75: Ovary - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 47: Leukemia - Hemostasis" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 11 "Nucleoplasm, Cytosol" "HPA041093: " "unprognostic (1.45e-1)" "unprognostic (1.85e-1)" "unprognostic (1.79e-1)" "unprognostic (1.30e-1)" "unprognostic (8.22e-3)" "unprognostic (2.87e-2)" "unprognostic (4.19e-1)" "unprognostic (1.24e-3)" "unprognostic (2.26e-1)" "unprognostic (2.55e-2)" "unprognostic (1.12e-1)" "unprognostic (1.63e-1)" "unprognostic (3.56e-1)" "unprognostic (1.05e-1)" "unprognostic (2.08e-2)" "unprognostic (2.06e-1)" "unprognostic (1.17e-1)" "unprognostic (3.48e-1)" "unprognostic (2.73e-1)" "unprognostic (2.20e-1)" "unprognostic (1.88e-3)" "potential prognostic unfavorable (9.18e-4)" "unprognostic (1.99e-1)" "unprognostic (6.45e-2)" "unprognostic (2.56e-2)" "unprognostic (5.29e-2)" "unprognostic (8.32e-2)" "unprognostic (8.32e-2)" MEX3C "FLJ38871, RKHD2, RNF194" ENSG00000176624 "Mex-3 RNA binding family member C" Q5U5Q3 18 51174550-51218333 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 110.5" "Group enriched" "Detected in many" 4 "Early spermatids: 773.2;Late spermatids: 848.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 9.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040603 Uncertain Approved Vesicles NA NA "Cluster 32: Basophils - Transcription" "Cluster 39: Testis - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 13: Non-specific - Mixed function" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 17 Vesicles "HPA040603: " "unprognostic (1.19e-1)" "unprognostic (3.16e-1)" "unprognostic (7.86e-3)" "unprognostic (3.09e-2)" "unprognostic (4.50e-2)" "unprognostic (1.85e-1)" "unprognostic (3.66e-2)" "unprognostic (9.49e-3)" "unprognostic (4.34e-1)" "unprognostic (1.02e-1)" "potential prognostic favorable (3.22e-5)" "unprognostic (1.66e-3)" "unprognostic (2.79e-1)" "potential prognostic unfavorable (2.53e-4)" "unprognostic (4.81e-3)" "unprognostic (1.14e-1)" "unprognostic (1.18e-1)" "unprognostic (1.13e-1)" "unprognostic (8.02e-2)" "unprognostic (3.75e-1)" "unprognostic (8.44e-2)" "unprognostic (3.27e-3)" "unprognostic (1.52e-1)" "unprognostic (4.91e-2)" "unprognostic (8.78e-2)" "unprognostic (8.66e-2)" "unprognostic (2.86e-2)" "unprognostic (2.43e-1)" "unprognostic (2.05e-1)" "unprognostic (1.72e-1)" "unprognostic (4.44e-2)" MEX3D "KIAA2031, OK/SW-cl.4, RKHD1, RNF193, Tino" ENSG00000181588 "Mex-3 RNA binding family member D" Q86XN8 19 1554672-1568325 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "testis: 73.9" "Cell type enriched" "Detected in many" 6 "Late spermatids: 604.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Fibroblasts, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065385 Approved NA NA "Cluster 67: Testis - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 23: Non-specific - Transcription" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" "HPA065385: " "unprognostic (1.01e-2)" "unprognostic (9.63e-2)" "unprognostic (9.27e-2)" "unprognostic (5.18e-2)" "unprognostic (3.32e-1)" "unprognostic (1.30e-1)" "unprognostic (1.51e-1)" "unprognostic (2.98e-2)" "unprognostic (5.15e-3)" "unprognostic (2.79e-1)" "unprognostic (5.90e-3)" "unprognostic (8.87e-2)" "unprognostic (1.41e-2)" "unprognostic (1.03e-2)" "potential prognostic unfavorable (5.96e-4)" "unprognostic (4.74e-3)" "unprognostic (5.37e-3)" "unprognostic (2.06e-1)" "unprognostic (2.39e-1)" "unprognostic (1.53e-1)" "unprognostic (1.00e-2)" "unprognostic (1.30e-1)" "unprognostic (1.58e-1)" "unprognostic (3.79e-2)" "unprognostic (2.00e-1)" "potential prognostic favorable (2.64e-4)" "unprognostic (1.58e-1)" "unprognostic (1.25e-1)" "unprognostic (1.50e-1)" "unprognostic (1.12e-1)" "unprognostic (4.68e-2)" MFAP1 AMP ENSG00000140259 "Microfibril associated protein 1" P55081 15 43804492-43824690 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 183.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015583, HPA042370" Uncertain Supported Nucleoplasm,Centrosome NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 16: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 139 Nucleoplasm Centrosome "HPA015583: , HPA042370: " "unprognostic (2.97e-1)" "unprognostic (2.01e-2)" "unprognostic (2.21e-1)" "unprognostic (6.35e-2)" "unprognostic (4.30e-2)" "unprognostic (3.40e-2)" "unprognostic (3.39e-1)" "unprognostic (8.97e-2)" "unprognostic (3.58e-2)" "unprognostic (2.07e-2)" "validated prognostic favorable (2.07e-9)" "validated prognostic favorable (1.55e-4)" "unprognostic (3.67e-2)" "validated prognostic unfavorable (5.12e-6)" "validated prognostic unfavorable (2.80e-4)" "unprognostic (7.31e-2)" "unprognostic (9.89e-2)" "unprognostic (1.18e-1)" "unprognostic (1.73e-2)" "unprognostic (5.79e-2)" "unprognostic (9.44e-2)" "unprognostic (2.74e-2)" "unprognostic (1.24e-2)" "unprognostic (1.54e-1)" "unprognostic (1.39e-1)" "unprognostic (1.97e-2)" "unprognostic (5.50e-2)" "unprognostic (1.03e-1)" "unprognostic (6.68e-2)" "unprognostic (6.70e-2)" "unprognostic (3.51e-2)" MFAP2 "MAGP, MAGP-1" ENSG00000117122 "Microfibril associated protein 2" P55001 1 16974502-16980632 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 2.4;Endometrial stromal cells: 2.3;Extravillous trophoblasts: 3.1;Fibroblasts: 2.4;Granulosa cells: 2.4;Late spermatids: 2.5;Lymphatic endothelial cells: 3.1;Medullary thymic epithelial cells: 2.4;Melanocytes: 3.0;Mesothelial cells: 1.6;Pituitary stem cells: 1.9" "Cell type enriched" "Detected in single" 10 "fibroblast: 1.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA007354 Enhanced "Secreted to extracellular matrix" "No annotated function" NA NA 40000 "Cluster 75: Ovary - Mixed function" "Cluster 3: Choroid plexus - Cilium" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" "HPA007354: " "unprognostic (5.81e-2)" "unprognostic (4.66e-2)" "unprognostic (6.42e-3)" "unprognostic (1.68e-1)" "unprognostic (3.71e-2)" "unprognostic (4.53e-1)" "unprognostic (3.00e-1)" "unprognostic (1.58e-1)" "unprognostic (1.12e-2)" "unprognostic (1.36e-1)" "potential prognostic unfavorable (3.94e-4)" "unprognostic (5.95e-2)" "unprognostic (5.55e-3)" "unprognostic (6.25e-3)" "unprognostic (1.04e-1)" "unprognostic (1.02e-1)" "unprognostic (1.05e-1)" "unprognostic (3.15e-1)" "unprognostic (1.61e-1)" "unprognostic (1.81e-1)" "unprognostic (7.75e-2)" "unprognostic (1.23e-2)" "unprognostic (2.09e-1)" "unprognostic (1.08e-1)" "unprognostic (1.77e-1)" "unprognostic (3.37e-2)" "unprognostic (1.28e-2)" "unprognostic (3.56e-3)" "unprognostic (1.15e-1)" "unprognostic (1.50e-1)" "unprognostic (1.65e-1)" MFAP3 ENSG00000037749 "Microfibril associated protein 3" P55082 5 154038959-154220478 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Colon - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015883, HPA049198" Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 28: Liver & Adrenal gland - Secretion" "Cluster 5: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 1 "Golgi apparatus" Nucleoplasm "HPA015883: , HPA049198: " "unprognostic (1.98e-2)" "unprognostic (3.96e-2)" "unprognostic (1.10e-1)" "unprognostic (2.70e-3)" "unprognostic (1.38e-2)" "unprognostic (3.68e-2)" "unprognostic (1.98e-1)" "unprognostic (4.64e-2)" "unprognostic (1.51e-1)" "unprognostic (1.40e-2)" "potential prognostic favorable (1.26e-6)" "unprognostic (1.73e-3)" "unprognostic (3.32e-1)" "unprognostic (8.64e-3)" "unprognostic (6.92e-2)" "unprognostic (8.07e-2)" "unprognostic (1.33e-2)" "unprognostic (1.34e-2)" "unprognostic (1.25e-1)" "unprognostic (2.46e-2)" "unprognostic (4.71e-2)" "unprognostic (1.10e-1)" "potential prognostic unfavorable (3.36e-4)" "unprognostic (6.07e-2)" "unprognostic (6.27e-2)" "unprognostic (1.55e-1)" "unprognostic (9.81e-2)" "unprognostic (2.17e-3)" "unprognostic (2.10e-1)" "unprognostic (3.94e-2)" "unprognostic (2.93e-1)" MFAP3L "KIAA0626, NYD-sp9" ENSG00000198948 "Microfibril associated protein 3 like" O75121 4 169986597-170033031 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 42.4" "Cell type enriched" "Detected in many" 5 "Late spermatids: 3094.5" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 219.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 5.7;eosinophil: 1.8;neutrophil: 3.5" "Lineage enriched" "Detected in single" 8 "granulocytes: 5.7" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Colon - Enteric glia cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017986, HPA062306, HPA077490" Enhanced Supported "Nucleoplasm,Cell Junctions" "Intracellular and membrane" "No annotated function" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 27: Breast cancer - Unknown function" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" Nucleoplasm "Cell Junctions" "HPA017986: , HPA062306: , HPA077490: " "unprognostic (6.06e-3)" "unprognostic (5.83e-3)" "unprognostic (1.83e-1)" "unprognostic (8.59e-3)" "unprognostic (1.99e-2)" "unprognostic (1.38e-2)" "unprognostic (1.52e-1)" "unprognostic (1.15e-1)" "unprognostic (4.79e-2)" "unprognostic (2.13e-1)" "validated prognostic favorable (1.02e-8)" "validated prognostic favorable (1.37e-4)" "potential prognostic favorable (1.23e-4)" "unprognostic (4.51e-2)" "unprognostic (4.81e-2)" "unprognostic (7.19e-3)" "unprognostic (4.85e-2)" "unprognostic (8.22e-2)" "unprognostic (3.48e-2)" "unprognostic (2.72e-1)" "unprognostic (8.98e-2)" "unprognostic (2.55e-1)" "unprognostic (1.80e-1)" "unprognostic (1.32e-1)" "unprognostic (4.67e-1)" "unprognostic (1.15e-1)" "unprognostic (3.53e-1)" "potential prognostic unfavorable (4.66e-4)" "unprognostic (2.91e-1)" "potential prognostic unfavorable (2.39e-5)" "unprognostic (1.50e-1)" MFAP4 ENSG00000166482 "Microfibril associated protein 4" P55083 17 19383442-19387190 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 1055.6" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 309.6;Fibroblasts: 590.2;Hepatic stellate cells: 225.9;Müller glia: 82.2;Ovarian stromal cells: 136.1;Pericytes: 83.5;Peritubular myoid cells: 206.9;Smooth muscle cells: 238.5;Vascular smooth muscle cells: 164.5" "Group enriched" "Detected in some" 49 "fibroblast: 140.1;vascular associated smooth muscle cell: 61.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 11 "eosinophil: 1.0;intermediate monocyte: 1.8;non-classical monocyte: 1.9" "Group enriched" "Detected in many" 15 "granulocytes: 1.0;monocytes: 1.9" "Cancer enhanced" "Detected in many" "Bone cancer: 118.8;Neuroblastoma: 110.6" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Colon - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblasts_1, Minor Salivary Gland - Fibroblasts, Pancreas - Fibroblasts, Pituitary gland - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Testis - Peritubular cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA054097 Supported Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" "Cell adhesion" NA NA 15000000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 74 "Endoplasmic reticulum" "HPA054097: " "unprognostic (2.39e-3)" "unprognostic (4.63e-2)" "unprognostic (1.17e-2)" "unprognostic (7.60e-2)" "unprognostic (1.93e-1)" "unprognostic (2.05e-1)" "unprognostic (9.73e-2)" "unprognostic (3.66e-2)" "potential prognostic favorable (3.73e-4)" "unprognostic (3.67e-2)" "unprognostic (8.85e-2)" "unprognostic (2.62e-2)" "potential prognostic unfavorable (7.70e-5)" "unprognostic (2.81e-2)" "unprognostic (3.73e-3)" "unprognostic (1.19e-3)" "unprognostic (8.63e-2)" "unprognostic (1.90e-2)" "unprognostic (1.61e-1)" "potential prognostic unfavorable (2.68e-4)" "unprognostic (3.66e-2)" "unprognostic (1.59e-1)" "unprognostic (3.47e-2)" "unprognostic (1.64e-1)" "unprognostic (2.46e-2)" "unprognostic (4.31e-2)" "unprognostic (1.91e-2)" "unprognostic (1.03e-2)" "unprognostic (4.85e-2)" "unprognostic (4.11e-2)" "unprognostic (9.73e-2)" MFAP5 "MAGP2, MP25" ENSG00000197614 "Microfibril associated protein 5" Q13361 12 8637346-8662888 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Aortic aneurysm, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 184.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 114.3;Extravillous trophoblasts: 1767.1;Fibro-adipogenic progenitors: 356.5;Fibroblasts: 759.2;Migrating cytotrophoblasts: 466.2;Syncytiotrophoblasts: 318.9" "Cell type enriched" "Detected in some" 4 "fibroblast: 8.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.0" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "testis cancer: 126.5" "Lung - Fibroblasts_2, Prostate - Smooth muscle cells, Skin - Fibroblasts_2" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 10 "spinal cord: 56.8" HPA010553 Enhanced "Secreted to extracellular matrix" "No annotated function" NA NA 970000 "Cluster 35: Neutrophils - Protein binding" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 2: Neurons - Nucleosome" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" "HPA010553: " "unprognostic (1.92e-2)" "unprognostic (3.06e-2)" "unprognostic (6.11e-2)" "unprognostic (3.94e-3)" "unprognostic (6.90e-2)" "unprognostic (1.52e-1)" "unprognostic (7.61e-2)" "unprognostic (1.20e-1)" "unprognostic (3.20e-2)" "unprognostic (8.62e-3)" "unprognostic (4.36e-2)" "potential prognostic unfavorable (5.98e-4)" "unprognostic (4.87e-3)" "unprognostic (4.77e-3)" "unprognostic (3.21e-2)" "unprognostic (2.99e-1)" "unprognostic (3.52e-2)" "unprognostic (4.91e-2)" "unprognostic (9.40e-3)" "unprognostic (4.39e-3)" "unprognostic (1.92e-1)" "unprognostic (1.38e-2)" "unprognostic (2.69e-1)" "unprognostic (7.56e-2)" "unprognostic (4.11e-3)" "unprognostic (2.95e-1)" "unprognostic (4.10e-3)" "unprognostic (1.65e-1)" MFF "C2orf33, GL004" ENSG00000168958 "Mitochondrial fission factor" Q9GZY8 2 227325151-227357833 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Early spermatids: 894.0;Late primary spermatocytes: 1010.9;Late spermatids: 3172.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010968, HPA074625" Enhanced Supported "Mitochondria,Principal piece" No No 15000 "Cluster 22: Eosinophils - Transcription" "Cluster 67: Testis - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 13 Mitochondria "Principal piece" "HPA010968: , HPA074625: " "unprognostic (2.76e-1)" "unprognostic (6.85e-3)" "unprognostic (5.10e-2)" "unprognostic (1.68e-1)" "unprognostic (7.94e-2)" "unprognostic (1.61e-1)" "unprognostic (9.66e-2)" "unprognostic (2.83e-2)" "unprognostic (1.82e-2)" "unprognostic (9.37e-3)" "potential prognostic favorable (2.12e-5)" "unprognostic (1.56e-3)" "unprognostic (1.22e-1)" "validated prognostic unfavorable (6.74e-7)" "validated prognostic unfavorable (1.16e-4)" "potential prognostic unfavorable (4.52e-4)" "unprognostic (3.58e-1)" "unprognostic (1.57e-1)" "unprognostic (2.62e-1)" "unprognostic (1.31e-1)" "unprognostic (3.09e-1)" "unprognostic (1.14e-1)" "unprognostic (7.62e-2)" "unprognostic (3.22e-3)" "unprognostic (9.10e-2)" "unprognostic (7.54e-2)" "unprognostic (2.28e-1)" "unprognostic (4.43e-2)" "unprognostic (3.30e-2)" "unprognostic (1.91e-1)" "unprognostic (1.29e-1)" MFGE8 "BA46, EDIL1, hP47, HsT19888, MFG-E8, OAcGD3S, SED1, SPAG10" ENSG00000140545 "Milk fat globule EGF and factor V/VIII domain containing" Q08431 15 88898683-88913468 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion, Fertilization" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "blood vessel: 2177.9" "Cell type enhanced" "Detected in many" "Breast lactating cells: 2432.2;Breast secretory cells: 484.1;Decidual stromal cells: 646.3;Fibroblasts: 312.1;Pericytes: 441.1;Rod photoreceptor cells: 499.1;Smooth muscle cells: 271.5;Thymic myoid cells: 270.6;Vascular smooth muscle cells: 747.9" "Cell type enhanced" "Detected in many" "pericyte: 250.7;vascular associated smooth muscle cell: 271.2" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 513.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 15.9" "Group enriched" "Detected in many" 7 "granulocytes: 5.7;NK-cells: 7.7;T-cells: 15.9" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Kidney - Fibroblasts, Pituitary gland - Endothelial cells, Spleen - Fibroblasts_2, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002753, HPA002807" Enhanced Approved Cytosol "Secreted to blood" "Cell adhesion" NA NA 2830000 19000 "Cluster 16: Non-specific - Cell proliferation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 30: White matter - Myelination" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 1 Cytosol "CAB002753: , HPA002807: " "unprognostic (6.99e-2)" "unprognostic (3.87e-2)" "unprognostic (2.03e-1)" "unprognostic (7.21e-2)" "unprognostic (2.33e-2)" "unprognostic (1.11e-1)" "unprognostic (2.23e-1)" "unprognostic (6.13e-2)" "unprognostic (2.25e-1)" "unprognostic (4.50e-3)" "unprognostic (1.09e-2)" "potential prognostic favorable (2.67e-4)" "potential prognostic unfavorable (6.02e-5)" "unprognostic (1.48e-1)" "unprognostic (2.04e-1)" "unprognostic (4.19e-1)" "potential prognostic unfavorable (4.02e-5)" "unprognostic (3.72e-2)" "unprognostic (2.61e-2)" "unprognostic (8.20e-2)" "potential prognostic unfavorable (9.24e-4)" "unprognostic (5.26e-2)" "unprognostic (1.16e-1)" "unprognostic (2.93e-1)" "unprognostic (4.22e-2)" "unprognostic (1.65e-2)" "unprognostic (3.01e-2)" "potential prognostic unfavorable (5.21e-4)" "unprognostic (2.12e-1)" "unprognostic (5.95e-2)" "unprognostic (3.24e-1)" MFHAS1 "LRRC65, MASL1" ENSG00000147324 "Multifunctional ROCO family signaling regulator 1" Q9Y4C4 8 8783354-8893630 "Disease related genes, Predicted intracellular proteins" "Immunity, Inflammatory response, Innate immunity" "Signal transduction inhibitor" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 168.3;Distal convoluted tubule cells: 508.9;Ependymal cells: 100.7;Loop of henle epithelial cells: 322.1;Papillary tip epithelial cells: 130.2;Proximal tubule cells: 179.9;Renal collecting duct intercalated cells: 125.4;Renal collecting duct principal cells: 187.2;Renal connecting tubule cells: 479.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Spleen - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051213, HPA054471" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 7 Nucleoplasm Cytosol "HPA051213: , HPA054471: " "unprognostic (1.74e-2)" "unprognostic (2.62e-1)" "unprognostic (3.31e-1)" "unprognostic (9.57e-2)" "unprognostic (5.85e-3)" "unprognostic (4.01e-2)" "unprognostic (1.49e-1)" "unprognostic (9.92e-3)" "unprognostic (1.25e-2)" "unprognostic (1.64e-1)" "validated prognostic favorable (2.73e-6)" "validated prognostic favorable (5.47e-4)" "unprognostic (2.46e-1)" "unprognostic (1.39e-3)" "unprognostic (3.40e-1)" "unprognostic (2.30e-2)" "unprognostic (2.32e-1)" "unprognostic (6.93e-2)" "unprognostic (3.34e-3)" "unprognostic (3.94e-2)" "unprognostic (5.86e-3)" "unprognostic (1.42e-1)" "unprognostic (4.18e-2)" "unprognostic (2.78e-1)" "unprognostic (2.91e-2)" "unprognostic (3.77e-2)" "unprognostic (2.72e-2)" "unprognostic (1.74e-1)" "unprognostic (1.73e-1)" "unprognostic (2.91e-1)" "unprognostic (2.13e-2)" MFN1 FLJ20693 ENSG00000171109 "Mitofusin 1" Q8IWA4 3 179347709-179394936 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033437, HPA059230" Approved Supported Mitochondria NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 12 Mitochondria "CAB033437: , HPA059230: " "unprognostic (5.94e-3)" "unprognostic (6.60e-2)" "unprognostic (1.13e-1)" "unprognostic (2.00e-1)" "unprognostic (1.81e-1)" "unprognostic (1.54e-1)" "unprognostic (9.18e-2)" "unprognostic (2.75e-2)" "unprognostic (2.95e-1)" "unprognostic (9.49e-3)" "unprognostic (7.36e-3)" "unprognostic (1.27e-1)" "unprognostic (9.87e-2)" "potential prognostic unfavorable (6.53e-4)" "unprognostic (7.03e-3)" "unprognostic (2.10e-1)" "unprognostic (7.63e-3)" "unprognostic (1.14e-1)" "unprognostic (2.60e-2)" "unprognostic (1.80e-2)" "unprognostic (1.01e-3)" "unprognostic (1.93e-3)" "unprognostic (1.22e-2)" "unprognostic (3.15e-1)" "unprognostic (6.43e-3)" "unprognostic (1.91e-1)" "unprognostic (1.96e-1)" "unprognostic (1.66e-1)" "unprognostic (1.95e-1)" "unprognostic (2.02e-2)" "unprognostic (2.66e-1)" MFN2 "CMT2A2, CPRP1, KIAA0214, MARF" ENSG00000116688 "Mitofusin 2" O95140 1 11980181-12015211 "Disease related genes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Autophagy, Unfolded protein response" Hydrolase "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 253.1;skeletal muscle: 290.9;tongue: 315.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 144.9;Neutrophils: 256.3;Platelets: 260.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030554, CAB079902" Uncertain Supported Mitochondria NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 19: Astrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 25 Mitochondria "CAB079902: , HPA030554: " "unprognostic (2.03e-1)" "unprognostic (2.68e-2)" "unprognostic (3.91e-2)" "unprognostic (2.74e-3)" "potential prognostic favorable (8.00e-4)" "unprognostic (3.71e-1)" "unprognostic (1.75e-1)" "unprognostic (1.93e-1)" "unprognostic (2.64e-1)" "unprognostic (7.47e-2)" "validated prognostic favorable (2.58e-8)" "validated prognostic favorable (2.81e-4)" "unprognostic (4.22e-3)" "unprognostic (3.10e-1)" "unprognostic (3.05e-2)" "unprognostic (1.31e-1)" "unprognostic (2.96e-1)" "unprognostic (7.22e-2)" "unprognostic (1.08e-1)" "unprognostic (2.60e-2)" "unprognostic (1.44e-1)" "unprognostic (1.43e-2)" "unprognostic (1.99e-2)" "unprognostic (7.49e-2)" "unprognostic (1.10e-1)" "unprognostic (3.58e-1)" "unprognostic (4.88e-1)" "unprognostic (6.91e-2)" "unprognostic (8.16e-2)" "unprognostic (6.10e-2)" "unprognostic (1.45e-1)" MFNG ENSG00000100060 "MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase" O00587 22 37469063-37486393 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Developmental protein, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 64.6" "Cell type enhanced" "Detected in many" "B-cells: 31.1;cDC: 36.0;Hofbauer cells: 37.3;Kupffer cells: 32.8;Lymphatic endothelial cells: 46.7;Megakaryocyte progenitors: 65.6;Megakaryocyte-Erythroid progenitors: 34.5;Megakaryocytes: 173.1;monocytes: 34.6;NK-cells: 41.7;Platelets: 138.0;T-cells: 35.3;Vascular endothelial cells: 39.9" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 16.1;endothelial cell: 25.7;leukocyte: 32.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Leukemia: 149.5;lymphoma: 165.2;Myeloma: 119.2" "Liver - Vascular endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048936, HPA056479" Approved Approved Vesicles "Intracellular and membrane" "Developmental protein" NA NA 60000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 47: Platelets - Hemostasis" Vesicles "HPA048936: , HPA056479: " "unprognostic (6.07e-2)" "unprognostic (3.47e-1)" "unprognostic (6.31e-2)" "unprognostic (8.93e-3)" "unprognostic (3.07e-2)" "unprognostic (1.53e-1)" "unprognostic (1.43e-1)" "unprognostic (1.38e-2)" "unprognostic (9.12e-3)" "unprognostic (1.26e-1)" "unprognostic (2.30e-3)" "unprognostic (2.56e-1)" "unprognostic (2.29e-1)" "unprognostic (2.28e-1)" "unprognostic (5.21e-2)" "potential prognostic favorable (3.92e-4)" "unprognostic (2.58e-1)" "unprognostic (7.56e-2)" "unprognostic (4.75e-1)" "unprognostic (1.74e-1)" "unprognostic (8.60e-2)" "unprognostic (2.88e-2)" "unprognostic (2.94e-2)" "unprognostic (1.57e-2)" "unprognostic (2.42e-1)" "unprognostic (3.39e-1)" "unprognostic (4.52e-1)" "unprognostic (2.46e-1)" "unprognostic (4.24e-2)" "unprognostic (3.21e-1)" "unprognostic (9.15e-2)" MFRP "C1QTNF5, FLJ30570, NNO2, rd6" ENSG00000235718 "Membrane frizzled-related protein" Q9BY79 11 119338942-119346705 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Microphthalmia, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 925 "choroid plexus: 314.9" "Cell type enriched" "Detected in some" 5 "Retinal pigment epithelial cells: 81.0" "Cell type enriched" "Detected in some" 13 "choroid plexus epithelial cell: 18.5" "Not detected" "Not detected" "Region enriched" "Detected in many" 15 "choroid plexus: 759.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "basal ganglia: 3.5;hippocampal formation: 11.8;pons and medulla: 10.3;thalamus: 8.4" "Group enriched" "Detected in all" 5 "medulla oblongata: 25.1;midbrain: 7.0;thalamus: 10.0" NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" 1 "unprognostic (8.23e-2)" "unprognostic (1.68e-1)" MFSD1 "FLJ14153, Minerva, UG0581B09" ENSG00000118855 "Major facilitator superfamily domain containing 1" Q9H3U5 3 158732198-158829719 "Predicted intracellular proteins, Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epicardial cells: 686.8;Esophageal apical cells: 426.5;Hofbauer cells: 287.1;Kupffer cells: 578.0;Macrophages: 315.6;Monocyte progenitors: 247.7;monocytes: 273.6;Platelets: 581.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "dendritic cells: 254.7;granulocytes: 246.6;monocytes: 289.1" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Lung - Macrophages, Pancreas - Macrophages, Skeletal muscle - Macrophages, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065858 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" "Plasma membrane" Cytosol "HPA065858: " "unprognostic (6.63e-2)" "unprognostic (2.83e-2)" "unprognostic (1.20e-1)" "potential prognostic favorable (3.52e-4)" "unprognostic (1.47e-1)" "unprognostic (1.70e-3)" "unprognostic (1.74e-1)" "unprognostic (4.18e-1)" "unprognostic (1.13e-1)" "unprognostic (5.52e-3)" "potential prognostic favorable (1.36e-6)" "unprognostic (5.48e-2)" "unprognostic (1.45e-2)" "unprognostic (3.37e-2)" "unprognostic (1.85e-1)" "unprognostic (1.19e-1)" "unprognostic (3.55e-2)" "unprognostic (2.84e-1)" "unprognostic (7.48e-2)" "unprognostic (4.61e-2)" "unprognostic (5.27e-3)" "unprognostic (7.82e-2)" "unprognostic (3.80e-2)" "unprognostic (3.44e-1)" "unprognostic (3.69e-2)" "unprognostic (1.31e-1)" "unprognostic (4.81e-2)" "unprognostic (2.20e-1)" "unprognostic (1.37e-1)" "unprognostic (3.43e-2)" "unprognostic (3.78e-1)" MFSD10 "IT10C3, TETRAN" ENSG00000109736 "Major facilitator superfamily domain containing 10" Q14728 4 2930561-2934834 "Predicted membrane proteins" "Apoptosis, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043209 Uncertain Approved "Nucleoplasm,Nuclear membrane" No No "Cluster 45: Eosinophils - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 15: Non-specific - Protein processing" 8 "Nuclear membrane" Nucleoplasm "HPA043209: " "unprognostic (2.21e-1)" "unprognostic (6.16e-3)" "unprognostic (1.26e-2)" "unprognostic (4.03e-3)" "unprognostic (1.56e-1)" "unprognostic (5.30e-2)" "unprognostic (3.51e-3)" "unprognostic (1.59e-1)" "unprognostic (2.20e-2)" "unprognostic (1.79e-1)" "unprognostic (4.73e-3)" "unprognostic (7.51e-3)" "unprognostic (9.35e-2)" "potential prognostic unfavorable (9.77e-6)" "unprognostic (1.18e-1)" "unprognostic (5.03e-2)" "unprognostic (1.09e-2)" "unprognostic (2.40e-2)" "unprognostic (1.99e-1)" "unprognostic (1.86e-1)" "unprognostic (4.01e-3)" "unprognostic (1.37e-1)" "unprognostic (1.05e-1)" "unprognostic (2.40e-3)" "unprognostic (4.40e-2)" "unprognostic (1.87e-1)" "unprognostic (7.92e-2)" "unprognostic (8.04e-2)" "unprognostic (2.06e-1)" "unprognostic (4.73e-2)" "unprognostic (1.05e-1)" MFSD11 "FLJ20226, FLJ22196" ENSG00000092931 "Major facilitator superfamily domain containing 11" O43934 17 76735865-76781449 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 234.9;Cone photoreceptor cells: 370.6;Early spermatids: 255.9;Late spermatids: 248.7;Myonuclei: 273.5;Rod photoreceptor cells: 284.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022001 Uncertain NA No "Cluster 33: Non-specific - ATP binding" "Cluster 42: Retina - Visual perception" "Cluster 16: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" 10 "HPA022001: " "unprognostic (3.42e-1)" "unprognostic (3.01e-2)" "unprognostic (2.74e-2)" "unprognostic (1.61e-2)" "unprognostic (9.77e-2)" "unprognostic (2.89e-1)" "unprognostic (1.00e-2)" "unprognostic (6.02e-2)" "unprognostic (1.41e-1)" "unprognostic (1.45e-2)" "potential prognostic favorable (5.84e-4)" "unprognostic (1.01e-1)" "unprognostic (1.59e-1)" "unprognostic (3.02e-3)" "potential prognostic unfavorable (1.20e-4)" "unprognostic (7.71e-2)" "unprognostic (8.64e-3)" "unprognostic (2.36e-1)" "unprognostic (8.27e-2)" "unprognostic (9.78e-2)" "unprognostic (9.76e-2)" "unprognostic (1.89e-1)" "unprognostic (9.99e-2)" "unprognostic (1.91e-2)" "unprognostic (1.51e-2)" "unprognostic (1.82e-1)" "unprognostic (1.62e-1)" "unprognostic (2.15e-1)" "unprognostic (5.32e-2)" "unprognostic (3.01e-2)" "unprognostic (1.23e-1)" MFSD12 "C19orf28, MGC20700, PP3501" ENSG00000161091 "Major facilitator superfamily domain containing 12" Q6NUT3 19 3538261-3574290 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Melanin biosynthesis, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 147.1;Extravillous trophoblasts: 214.9;Melanocytes: 313.6;pDCs: 116.1;Syncytiotrophoblasts: 153.5" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 5 "Skin Cutaneous Melanoma (TCGA): 609.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in all" 4 "Adrenocortical cancer: 183.3;skin cancer: 635.4" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042149, HPA043088" Uncertain NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 61: Schwann cells & Melanocytes - Mixed function" "HPA042149: , HPA043088: " "unprognostic (6.04e-2)" "unprognostic (1.19e-1)" "unprognostic (1.42e-2)" "unprognostic (2.68e-1)" "unprognostic (4.10e-2)" "unprognostic (5.96e-3)" "unprognostic (2.17e-2)" "unprognostic (1.79e-1)" "unprognostic (6.49e-2)" "unprognostic (2.33e-1)" "unprognostic (1.09e-1)" "unprognostic (4.71e-2)" "potential prognostic unfavorable (3.21e-4)" "unprognostic (1.02e-3)" "unprognostic (1.64e-2)" "unprognostic (6.50e-2)" "unprognostic (2.41e-1)" "unprognostic (1.25e-2)" "unprognostic (1.88e-2)" "unprognostic (1.61e-1)" "unprognostic (5.93e-2)" "unprognostic (9.46e-2)" "unprognostic (2.09e-1)" "potential prognostic favorable (3.40e-4)" "unprognostic (1.92e-1)" "unprognostic (2.34e-2)" "unprognostic (6.88e-2)" "unprognostic (5.51e-2)" "unprognostic (1.25e-1)" MFSD13A "bA18I14.8, C10orf77, FLJ22529, TMEM180" ENSG00000138111 "Major facilitator superfamily domain containing 13A" Q14CX5 10 102461395-102477045 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 33.6;Epicardial cells: 38.7;Syncytiotrophoblasts: 58.4;Tuft cells: 23.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018031 Uncertain Approved "Golgi apparatus,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 2: Non-specific - Mixed function" "Cluster 34: Non-specific - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 3 "Golgi apparatus, Cytosol" "HPA018031: " "unprognostic (2.41e-1)" "unprognostic (2.96e-1)" "unprognostic (3.42e-2)" "unprognostic (3.35e-2)" "unprognostic (1.62e-1)" "unprognostic (2.55e-1)" "potential prognostic favorable (5.91e-4)" "unprognostic (6.42e-2)" "unprognostic (2.04e-1)" "unprognostic (1.32e-1)" "unprognostic (8.55e-2)" "unprognostic (3.92e-1)" "unprognostic (1.85e-2)" "unprognostic (1.08e-1)" "unprognostic (2.62e-1)" "unprognostic (2.09e-1)" "unprognostic (1.51e-2)" "unprognostic (1.34e-1)" "unprognostic (2.48e-2)" "unprognostic (1.91e-1)" "unprognostic (1.97e-1)" "unprognostic (8.12e-2)" "unprognostic (1.81e-1)" "unprognostic (2.38e-2)" "unprognostic (5.14e-3)" "unprognostic (2.97e-2)" "unprognostic (5.50e-2)" "unprognostic (4.97e-2)" "unprognostic (7.75e-2)" MFSD14A "DKFZP564L0864, HIAT1" ENSG00000156875 "Major facilitator superfamily domain containing 14A" Q96MC6 1 100038095-100083377 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 123.7" "Cell type enhanced" "Detected in many" "Ependymal cells: 15.4;Epididymal basal cells: 16.2;Epididymal clear cells: 14.3;Oligodendrocytes: 24.1;Other brain neurons: 18.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 187.7" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA073127, HPA073681" Approved Approved Vesicles NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 15: Non-specific - Protein processing" Vesicles "HPA073127: , HPA073681: " "unprognostic (2.52e-1)" "unprognostic (1.83e-1)" "unprognostic (2.19e-1)" "unprognostic (6.64e-3)" "unprognostic (1.88e-1)" "unprognostic (1.33e-1)" "unprognostic (2.25e-1)" "unprognostic (2.15e-1)" "unprognostic (1.81e-1)" "potential prognostic favorable (5.87e-6)" "unprognostic (1.43e-3)" "unprognostic (1.75e-1)" "unprognostic (1.94e-3)" "unprognostic (1.95e-1)" "unprognostic (2.48e-2)" "unprognostic (2.29e-1)" "unprognostic (1.01e-1)" "unprognostic (2.44e-1)" "unprognostic (3.85e-2)" "unprognostic (3.16e-2)" "unprognostic (6.03e-3)" "unprognostic (2.12e-1)" "unprognostic (9.98e-2)" "unprognostic (1.12e-2)" "unprognostic (1.01e-1)" "unprognostic (1.04e-1)" "unprognostic (5.19e-1)" "unprognostic (6.62e-2)" "unprognostic (1.06e-1)" MFSD14B "FLJ14753, HIATL1" ENSG00000148110 "Major facilitator superfamily domain containing 14B" Q5SR56 9 94374569-94461042 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 443.2;Neutrophils: 278.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017978 Approved Nucleoplasm,Cytosol NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 43: Hindbrain - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 61 "Nucleoplasm, Cytosol" "HPA017978: " "unprognostic (1.64e-1)" "unprognostic (1.05e-1)" "unprognostic (1.52e-1)" "unprognostic (4.28e-2)" "unprognostic (1.38e-1)" "unprognostic (2.11e-1)" "unprognostic (3.61e-2)" "unprognostic (6.48e-2)" "unprognostic (1.15e-2)" "unprognostic (4.78e-3)" "unprognostic (1.55e-1)" "unprognostic (1.22e-1)" "unprognostic (1.92e-3)" "unprognostic (2.90e-3)" "unprognostic (3.80e-1)" "unprognostic (6.10e-2)" "unprognostic (1.81e-1)" "unprognostic (3.68e-1)" "unprognostic (3.84e-2)" "unprognostic (1.28e-2)" "unprognostic (1.86e-1)" "unprognostic (3.51e-2)" "unprognostic (1.52e-1)" "unprognostic (1.86e-1)" "unprognostic (1.87e-1)" "unprognostic (1.13e-1)" "unprognostic (9.51e-2)" "unprognostic (1.59e-1)" "unprognostic (1.38e-1)" MFSD2A "FLJ14490, MFSD2, SLC59A1" ENSG00000168389 "Major facilitator superfamily domain containing 2A" Q8NA29 1 39955112-39969968 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid transport, Symport, Transport" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 92.1;liver: 153.9;seminal vesicle: 75.3;skin 1: 84.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 353.3;Enterocytes: 345.7;Epididymal efferent duct absorptive cells: 262.4;Epididymal principal cells: 323.0;Hepatocytes: 354.4;Sertoli cells: 102.7" "Cell type enriched" "Detected in many" 34 "endothelial cell: 392.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "classical monocyte: 13.2;intermediate monocyte: 6.6;myeloid DC: 14.7;plasmacytoid DC: 24.4" "Group enriched" "Detected in many" 12 "dendritic cells: 24.4;monocytes: 13.2" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary gland basal cells, Skin - Keratinocyte (other), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043107 Uncertain Approved "Plasma membrane,Cytosol,Cytoplasmic bodies" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 47: Endothelial cells - Vasculature" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 93: Hepatocytes - Bile production & excretion" "Plasma membrane, Cytosol" "Cytoplasmic bodies" "HPA043107: " "unprognostic (5.01e-2)" "unprognostic (1.60e-1)" "unprognostic (2.81e-1)" "unprognostic (1.85e-2)" "potential prognostic favorable (1.75e-4)" "unprognostic (7.18e-2)" "unprognostic (1.14e-1)" "unprognostic (2.27e-1)" "unprognostic (5.91e-2)" "potential prognostic unfavorable (1.87e-5)" "unprognostic (5.12e-3)" "unprognostic (3.93e-1)" "unprognostic (5.25e-2)" "unprognostic (2.11e-3)" "unprognostic (1.19e-3)" "unprognostic (3.06e-1)" "unprognostic (3.93e-2)" "unprognostic (4.47e-2)" "unprognostic (1.14e-1)" "unprognostic (3.65e-2)" "unprognostic (3.45e-1)" "unprognostic (3.53e-1)" "unprognostic (2.69e-2)" "unprognostic (2.54e-1)" "unprognostic (1.87e-1)" "unprognostic (9.29e-2)" "unprognostic (2.56e-1)" "unprognostic (6.46e-2)" "unprognostic (3.01e-2)" MFSD2B SLC59A2 ENSG00000205639 "Major facilitator superfamily domain containing 2B" A6NFX1 2 24010081-24063321 "Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 21 "bone marrow: 11.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 42.9;Erythrocyte progenitors: 88.3;Mast cells: 22.4;Megakaryocyte progenitors: 45.8;Megakaryocyte-Erythroid progenitors: 60.2;Megakaryocytes: 43.3;Platelets: 180.5" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "basophil: 2.9" "Lineage enriched" "Detected in single" 24 "granulocytes: 2.9" "Cancer enriched" "Detected in single" 16 "Leukemia: 2.9" "Spleen - Erythrocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA044145 Enhanced NA NA "Cluster 15: Bone marrow - Innate immune response" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 47: Leukemia - Hemostasis" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" "HPA044145: " MFSD3 ENSG00000167700 "Major facilitator superfamily domain containing 3" Q96ES6 8 144509070-144511213 "Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 54.0;Epididymal principal cells: 63.8;Esophageal suprabasal cells: 47.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056013 Uncertain Approved Vesicles NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 70: Non-specific - Protein processing" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 8: Non-specific - Secretory pathway" 9 Vesicles "HPA056013: " "unprognostic (2.23e-1)" "unprognostic (2.20e-2)" "unprognostic (1.60e-1)" "unprognostic (1.27e-2)" "unprognostic (2.01e-1)" "unprognostic (3.27e-2)" "unprognostic (1.23e-1)" "unprognostic (2.44e-1)" "unprognostic (9.61e-3)" "unprognostic (1.04e-1)" "unprognostic (2.91e-1)" "unprognostic (1.71e-3)" "potential prognostic favorable (3.11e-4)" "unprognostic (5.49e-2)" "unprognostic (1.14e-1)" "unprognostic (4.80e-3)" "unprognostic (3.73e-2)" "unprognostic (1.02e-1)" "unprognostic (1.70e-1)" "unprognostic (2.78e-1)" "unprognostic (9.36e-2)" "unprognostic (3.05e-2)" "unprognostic (3.41e-2)" "unprognostic (1.09e-1)" "unprognostic (2.89e-2)" "unprognostic (5.64e-2)" "unprognostic (5.37e-2)" "unprognostic (1.80e-2)" "unprognostic (2.93e-1)" "unprognostic (9.39e-2)" "unprognostic (2.17e-1)" MFSD4A "DKFZp761N1114, FLJ25004, FLJ34577, MFSD4, SLC60A1, UNQ3064" ENSG00000174514 "Major facilitator superfamily domain containing 4A" Q8N468 1 205568885-205602918 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 31.9;kidney: 62.3;stomach 1: 125.1" "Group enriched" "Detected in many" 4 "Parietal cells: 917.5;Retinal bipolar cells: 238.5" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 17.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 4.7" "Adipose subcutaneous - Endothelial cells, Kidney - Ascending Loop of Henle cells, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Somatotropes, Skin - Eccrine sweat gland cells, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "amygdala: 19.6;cerebellum: 25.5;cerebral cortex: 77.8;hippocampal formation: 43.0" HPA055407 Approved NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 97: Non-specific - Cellular respiration" 168 "HPA055407: " "unprognostic (8.15e-2)" "potential prognostic favorable (5.12e-4)" "unprognostic (1.92e-2)" "unprognostic (2.28e-1)" "unprognostic (2.92e-1)" "unprognostic (1.11e-1)" "unprognostic (6.48e-2)" "unprognostic (5.58e-3)" "unprognostic (6.56e-3)" "potential prognostic favorable (6.84e-6)" "unprognostic (1.68e-2)" "unprognostic (2.70e-1)" "potential prognostic favorable (4.16e-4)" "unprognostic (1.86e-1)" "unprognostic (5.05e-2)" "unprognostic (2.07e-1)" "unprognostic (5.77e-2)" "unprognostic (1.31e-3)" "unprognostic (8.20e-3)" "unprognostic (2.53e-2)" "unprognostic (6.39e-2)" "unprognostic (6.51e-3)" "unprognostic (1.47e-1)" "unprognostic (4.47e-1)" "unprognostic (1.72e-2)" "unprognostic (2.86e-1)" MFSD4B "KIAA1919, MGC33953, SLC60A2" ENSG00000173214 "Major facilitator superfamily domain containing 4B" Q5TF39 6 111259327-111445354 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Sugar transport, Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 627.6;Cardiomyocytes: 795.6;Endometrial stromal cells: 863.3;Epicardial cells: 1018.8;Fibro-adipogenic progenitors: 504.6;Myonuclei: 468.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA031784 Approved "Intracellular and membrane" Transport NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 2 "HPA031784: " "unprognostic (7.86e-2)" "unprognostic (5.45e-2)" "unprognostic (2.89e-3)" "unprognostic (4.54e-1)" "unprognostic (4.70e-2)" "unprognostic (4.19e-1)" "unprognostic (3.71e-1)" "potential prognostic unfavorable (4.54e-4)" "unprognostic (3.11e-2)" "unprognostic (1.09e-1)" "unprognostic (1.52e-1)" "unprognostic (3.32e-1)" "unprognostic (2.81e-1)" "unprognostic (3.49e-2)" "unprognostic (1.98e-1)" "unprognostic (1.08e-1)" "unprognostic (5.24e-2)" "unprognostic (8.05e-2)" "unprognostic (1.81e-3)" "unprognostic (2.66e-2)" "unprognostic (4.13e-2)" "unprognostic (2.69e-3)" "potential prognostic favorable (2.54e-4)" "unprognostic (5.10e-2)" "unprognostic (4.60e-2)" "unprognostic (2.49e-1)" "unprognostic (3.58e-2)" "unprognostic (7.97e-2)" MFSD5 "HsMOT2, MGC11308, SLC61A1" ENSG00000182544 "Major facilitator superfamily domain containing 5" Q6N075 12 53251251-53254406 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 44.6;Esophageal apical cells: 221.0;Esophageal suprabasal cells: 55.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039773 Uncertain NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 27: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 57 "HPA039773: " "unprognostic (2.93e-1)" "unprognostic (1.63e-2)" "unprognostic (2.41e-1)" "unprognostic (2.03e-1)" "unprognostic (4.83e-1)" "unprognostic (1.31e-1)" "potential prognostic unfavorable (3.99e-4)" "unprognostic (2.63e-2)" "unprognostic (2.64e-1)" "unprognostic (4.95e-2)" "unprognostic (3.63e-2)" "unprognostic (6.40e-3)" "unprognostic (3.03e-2)" "validated prognostic unfavorable (6.56e-5)" "validated prognostic unfavorable (3.64e-5)" "potential prognostic unfavorable (3.33e-4)" "unprognostic (4.86e-2)" "unprognostic (2.09e-1)" "unprognostic (2.26e-1)" "unprognostic (1.91e-1)" "unprognostic (1.91e-1)" "unprognostic (3.83e-2)" "unprognostic (9.06e-2)" "unprognostic (3.31e-2)" "unprognostic (5.54e-3)" "unprognostic (2.23e-1)" "unprognostic (1.07e-1)" "unprognostic (5.22e-2)" "unprognostic (1.64e-1)" "unprognostic (1.34e-1)" "unprognostic (2.67e-1)" MFSD6 FLJ20160 ENSG00000151690 "Major facilitator superfamily domain containing 6" Q6ZSS7 2 190408355-190509205 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Corticotrophs: 282.7;Podocytes: 246.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Adrenal gland - Adrenal cortex cells, Spleen - Endothelial cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022274 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 73: Brain - Neuronal signaling" "Cluster 45: Non-specific - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 9: T-cells - Adaptive immunity: Regulation" 31 "Nucleoplasm, Cytosol" "HPA022274: " "potential prognostic favorable (6.55e-8)" "unprognostic (4.11e-2)" "unprognostic (2.23e-1)" "unprognostic (8.64e-2)" "unprognostic (1.75e-1)" "unprognostic (3.35e-2)" "unprognostic (1.38e-1)" "unprognostic (2.28e-1)" "unprognostic (5.61e-3)" "unprognostic (3.24e-2)" "validated prognostic favorable (2.40e-6)" "validated prognostic favorable (5.34e-4)" "unprognostic (2.18e-1)" "unprognostic (2.54e-2)" "unprognostic (1.51e-1)" "unprognostic (3.57e-2)" "unprognostic (4.54e-2)" "unprognostic (2.25e-1)" "unprognostic (4.53e-1)" "unprognostic (3.40e-1)" "unprognostic (8.45e-2)" "unprognostic (1.94e-1)" "unprognostic (2.85e-1)" "unprognostic (3.52e-1)" "unprognostic (1.33e-1)" "unprognostic (9.61e-2)" "unprognostic (2.74e-1)" "unprognostic (9.09e-2)" "unprognostic (9.60e-2)" "unprognostic (9.90e-2)" "unprognostic (1.71e-1)" MFSD6L FLJ35773 ENSG00000185156 "Major facilitator superfamily domain containing 6 like" Q8IWD5 17 8797110-8799365 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 8.8;testis: 23.6" "Cell type enhanced" "Detected in many" "Early spermatids: 123.5;Late primary spermatocytes: 150.9;Late spermatids: 55.2;Respiratory ionocytes: 61.0;Salivary ionocytes: 32.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 8.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Breast glandular cells, Pituitary gland - Somatotropes, Skin - Inner root sheath cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" HPA023164 Uncertain NA NA "Cluster 21: Testis - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" "HPA023164: " "unprognostic (1.92e-2)" "potential prognostic favorable (5.95e-4)" "unprognostic (5.55e-3)" "unprognostic (1.04e-1)" "unprognostic (4.89e-2)" "unprognostic (3.12e-3)" "unprognostic (1.33e-3)" "unprognostic (3.79e-3)" "unprognostic (4.72e-3)" "unprognostic (2.69e-1)" "unprognostic (3.39e-1)" "unprognostic (6.66e-2)" "unprognostic (4.57e-2)" "unprognostic (3.93e-1)" "unprognostic (2.14e-2)" "unprognostic (8.65e-3)" "unprognostic (3.19e-2)" "unprognostic (6.84e-2)" "unprognostic (1.94e-1)" "unprognostic (1.25e-2)" "unprognostic (1.73e-2)" MFSD8 "CLN7, MGC33302" ENSG00000164073 "Major facilitator superfamily domain containing 8" Q8NHS3 4 127917799-127966034 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Disease variant, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 5 "Cardiomyocytes: 503.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044802 Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 77: Intestine - Digestion" "Cluster 55: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 13 Vesicles Nucleoplasm "HPA044802: " "unprognostic (1.22e-2)" "unprognostic (2.01e-2)" "unprognostic (7.38e-2)" "unprognostic (1.82e-2)" "unprognostic (2.42e-2)" "unprognostic (1.57e-2)" "unprognostic (1.21e-1)" "potential prognostic unfavorable (4.60e-4)" "unprognostic (1.70e-1)" "unprognostic (3.32e-2)" "potential prognostic favorable (3.55e-11)" "unprognostic (5.39e-3)" "unprognostic (2.34e-2)" "unprognostic (3.70e-2)" "unprognostic (3.86e-2)" "unprognostic (2.55e-1)" "unprognostic (7.78e-2)" "unprognostic (1.78e-2)" "unprognostic (2.18e-1)" "unprognostic (3.04e-1)" "unprognostic (2.23e-2)" "unprognostic (3.32e-2)" "potential prognostic unfavorable (1.38e-5)" "unprognostic (3.47e-3)" "potential prognostic favorable (1.92e-4)" "unprognostic (9.34e-2)" "unprognostic (2.05e-1)" "unprognostic (3.21e-2)" "unprognostic (2.38e-1)" "unprognostic (1.05e-1)" "unprognostic (6.80e-2)" MFSD9 MGC11332 ENSG00000135953 "Major facilitator superfamily domain containing 9" Q8NBP5 2 102714630-102736888 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055293, HPA061859" Approved Uncertain "Nucleoli,Nucleoli rim" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 60: Stomach - Digestion" "Cluster 35: Non-specific - DNA binding" "Cluster 19: Non-specific - Unknown function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" "Nucleoli, Nucleoli rim" "HPA055293: , HPA061859: " "unprognostic (9.19e-3)" "unprognostic (2.77e-3)" "unprognostic (4.79e-2)" "unprognostic (2.84e-2)" "unprognostic (2.86e-1)" "unprognostic (1.16e-2)" "unprognostic (7.40e-2)" "unprognostic (6.42e-2)" "unprognostic (3.15e-2)" "unprognostic (1.17e-1)" "potential prognostic favorable (2.53e-4)" "unprognostic (9.04e-3)" "unprognostic (3.10e-1)" "unprognostic (2.65e-2)" "unprognostic (3.11e-1)" "unprognostic (1.10e-2)" "unprognostic (2.64e-1)" "unprognostic (2.22e-1)" "unprognostic (2.55e-2)" "unprognostic (1.70e-1)" "unprognostic (2.22e-2)" "unprognostic (3.26e-1)" "unprognostic (2.77e-1)" "unprognostic (4.90e-2)" "unprognostic (1.11e-1)" "unprognostic (1.20e-3)" "unprognostic (1.46e-2)" "unprognostic (1.80e-1)" "unprognostic (1.63e-1)" "unprognostic (3.27e-2)" "unprognostic (6.40e-2)" MGA "FLJ12634, KIAA0518, MAD5, MXD5" ENSG00000174197 "MAX dimerization protein MGA" Q8IWI9 15 41621134-41773081 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Disease variant, Premature ovarian failure" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006304, HPA036876, HPA042278" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 7: Non-specific - Transcription" 30 Nucleoplasm Cytosol "HPA006304: , HPA036876: , HPA042278: " "unprognostic (1.59e-2)" "unprognostic (4.60e-2)" "unprognostic (1.44e-1)" "unprognostic (1.06e-1)" "unprognostic (2.75e-1)" "unprognostic (2.03e-2)" "unprognostic (1.96e-2)" "potential prognostic favorable (3.72e-4)" "unprognostic (1.91e-3)" "unprognostic (3.88e-2)" "validated prognostic favorable (8.52e-6)" "validated prognostic favorable (3.11e-5)" "unprognostic (6.86e-3)" "unprognostic (1.09e-2)" "unprognostic (1.94e-2)" "unprognostic (1.57e-1)" "unprognostic (7.58e-3)" "unprognostic (8.38e-2)" "unprognostic (3.01e-2)" "unprognostic (4.44e-3)" "unprognostic (2.17e-1)" "unprognostic (2.22e-1)" "unprognostic (1.50e-3)" "unprognostic (7.53e-2)" "unprognostic (7.33e-3)" "unprognostic (1.17e-2)" "unprognostic (1.60e-2)" "unprognostic (1.62e-1)" "unprognostic (4.88e-1)" "unprognostic (1.50e-1)" "unprognostic (2.29e-1)" MGAM MGA ENSG00000257335 Maltase-glucoamylase O43451 7 141907813-142106747 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Glycosidase, Hydrolase, Multifunctional enzyme" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 24.1;intestine: 82.5" "Cell type enhanced" "Detected in many" "Early spermatids: 173.0;Enterocytes: 255.5;Late spermatids: 308.0;Neutrophil progenitors: 152.9;Neutrophils: 491.1;Proximal tubule cells: 295.0;Renal collecting duct principal cells: 91.2" "Cell type enhanced" "Detected in many" "astrocyte: 29.6" "Cancer enriched" "Detected in some" 4 "Kidney Renal Clear Cell Carcinoma (TCGA): 7.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "neutrophil: 13.5" "Lineage enriched" "Detected in single" 102 "granulocytes: 13.5" "Cancer enhanced" "Detected in some" "breast cancer: 1.9;skin cancer: 4.3" "Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Kidney - Proximal tubular cells, Liver - Neutrophils, Lung - Neutrophils_2, Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Neutrophils, Spleen - Neutrophils_2, Thyroid gland - Neutrophils" "Region enriched" "Detected in single" 12 "olfactory bulb: 2.0" "Low region specificity" "Detected in all" HPA002270 Enhanced NA NA 1400000 "Cluster 4: Neutrophils - Degranulation" "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 12: Non-specific - Vasculature" "Cluster 69: Skin cancer - ECM organization" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 5 "HPA002270: " "unprognostic (1.79e-1)" "unprognostic (2.40e-2)" "unprognostic (3.63e-1)" "unprognostic (3.30e-1)" "potential prognostic favorable (2.74e-12)" "unprognostic (1.19e-3)" "unprognostic (8.39e-2)" "unprognostic (1.31e-2)" "unprognostic (1.42e-1)" MGAM2 ENSG00000257743 "Maltase-glucoamylase 2 (putative)" Q2M2H8 7 142111718-142222324 "Enzymes, Predicted membrane proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 5.5;pancreas: 3.8;salivary gland: 8.1" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 4.3;Early spermatids: 11.6;Lacrimal acinar cells: 15.4;Late primary spermatocytes: 3.9;Late spermatids: 9.9;Neutrophils: 5.7;Pancreatic duct cells: 3.9;Paneth cells: 3.9;Proximal tubule cells: 15.0;Salivary acinar cells: 9.1;Tuft cells: 34.6" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 4.2" "Group enriched" "Detected in some" 9 "Colon Adenocarcinoma (TCGA): 2.6;Pancreatic Adenocarcinoma (TCGA): 1.8;Rectum Adenocarcinoma (TCGA): 2.9;Stomach Adenocarcinoma (TCGA): 6.1" "Region enriched" "Detected in single" 5 "cerebral cortex: 1.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 16.4;Gastric cancer: 7.4;skin cancer: 5.6" "Adipose visceral - Neutrophils, Colon - Colon enterocytes, Lung - Neutrophils_2, Minor Salivary Gland - Minor salivary glandular cells, Spleen - Neutrophils_2, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA055697 Enhanced Approved Vesicles,Cytosol NA NA "Cluster 60: Stomach - Digestion" "Cluster 12: Non-specific - Vasculature" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 95: Tuft cells - Chemosensory signaling" Vesicles Cytosol "HPA055697: " "unprognostic (1.31e-1)" "unprognostic (3.18e-3)" "unprognostic (2.64e-1)" "unprognostic (6.46e-2)" "unprognostic (2.91e-1)" "unprognostic (5.59e-2)" "unprognostic (6.65e-3)" MGARP "C4orf49, CESP-1, HUMMR, OSAP" ENSG00000137463 "Mitochondria localized glutamic acid rich protein" Q8TDB4 4 139266165-139280225 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "adrenal gland: 215.3;retina: 108.3" "Cell type enhanced" "Detected in some" "Adrenal cortex cells: 120.1;Granulosa cells: 77.9;Müller glia: 352.9;Ocular epithelial cells: 408.6;Retinal amacrine cells: 59.2;Retinal bipolar cells: 76.7;Retinal horizontal cells: 100.2" "Cell type enhanced" "Detected in many" "midbrain-derived inhibitory: 7.3;upper rhombic lip: 8.3" "Group enriched" "Detected in some" 4 "Glioblastoma Multiforme (TCGA): 5.6;Kidney Renal Clear Cell Carcinoma (TCGA): 12.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "Rhabdoid: 47.0" "Adipose visceral - Mesothelial cells, Pituitary gland - Thyrotropes, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Region enhanced" "Detected in all" "basal ganglia: 28.0" "HPA015994, HPA070835" Enhanced Supported Mitochondria NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 2: Neurons - Nucleosome" "Cluster 5: Rhabdoid - Unknown function" "Cluster 100: Stratified epithelial cells - Barrier functions" 132 Mitochondria "HPA015994: , HPA070835: " "unprognostic (1.20e-2)" "potential prognostic unfavorable (1.06e-6)" "potential prognostic favorable (7.74e-7)" "unprognostic (5.94e-3)" "unprognostic (5.74e-2)" "unprognostic (1.44e-1)" "unprognostic (1.02e-1)" "unprognostic (1.52e-1)" MGAT1 "GLCNAC-TI, GLYT1, GNT-1, GnTI, MGAT" ENSG00000131446 "Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase" P26572 5 180784780-180815652 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "cDC: 276.5;Esophageal apical cells: 560.6;Extravillous trophoblasts: 407.8;Kupffer cells: 243.9;Macrophages: 369.5;monocytes: 534.4;Syncytiotrophoblasts: 620.6" "Cell type enhanced" "Detected in all" "endothelial cell: 106.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017432 Approved NA NA 6900000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 28: Liver & Adrenal gland - Secretion" "Cluster 12: Non-specific - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 4 "HPA017432: " "unprognostic (2.97e-2)" "unprognostic (4.21e-3)" "unprognostic (2.59e-1)" "unprognostic (1.96e-2)" "unprognostic (1.77e-1)" "unprognostic (3.10e-1)" "unprognostic (6.07e-2)" "unprognostic (6.23e-3)" "unprognostic (8.69e-2)" "unprognostic (1.97e-1)" "unprognostic (1.74e-3)" "unprognostic (8.27e-2)" "unprognostic (2.09e-1)" "unprognostic (2.99e-2)" "unprognostic (2.00e-1)" "unprognostic (1.90e-1)" "unprognostic (1.99e-1)" "unprognostic (1.05e-1)" "unprognostic (1.00e-1)" "unprognostic (1.53e-1)" "unprognostic (7.40e-3)" "unprognostic (7.09e-2)" "unprognostic (4.85e-2)" "unprognostic (2.16e-1)" "unprognostic (3.60e-2)" "unprognostic (1.89e-1)" "unprognostic (2.17e-1)" "unprognostic (3.37e-2)" "unprognostic (1.03e-2)" "unprognostic (9.78e-3)" "unprognostic (6.97e-2)" MGAT2 GNT-II ENSG00000168282 "Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase" Q10469 14 49620799-49623481 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 71.1;Plasma cells: 68.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Macrophages, Liver - Hepatocytes, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043721, HPA056824" Approved Supported "Golgi apparatus" NA Yes 2200000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 57: Testis - Spermatogenesis" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 108: Fibroblasts - ECM organization" 6 "Golgi apparatus" "HPA043721: , HPA056824: " "unprognostic (2.23e-1)" "unprognostic (1.43e-1)" "unprognostic (8.03e-2)" "unprognostic (1.24e-1)" "unprognostic (1.47e-2)" "unprognostic (7.78e-2)" "unprognostic (1.21e-1)" "unprognostic (6.58e-2)" "unprognostic (4.29e-2)" "unprognostic (2.02e-3)" "potential prognostic favorable (1.02e-4)" "unprognostic (2.35e-1)" "unprognostic (3.69e-1)" "unprognostic (3.94e-2)" "unprognostic (2.45e-1)" "unprognostic (2.46e-2)" "unprognostic (1.79e-2)" "unprognostic (7.98e-2)" "unprognostic (1.50e-2)" "unprognostic (3.43e-1)" "unprognostic (2.40e-3)" "unprognostic (1.33e-1)" "unprognostic (3.55e-2)" "unprognostic (3.47e-2)" "unprognostic (7.52e-2)" "unprognostic (4.13e-3)" "unprognostic (5.76e-2)" "unprognostic (2.24e-1)" "unprognostic (1.21e-1)" "unprognostic (3.95e-2)" "unprognostic (8.82e-3)" MGAT3 GNT-III ENSG00000128268 "Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase" Q09327 22 39457012-39492194 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 41.3;intestine: 26.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 32.0;Brain excitatory neurons: 40.4;Brain inhibitory neurons: 40.4;Early spermatids: 36.3;Enterocytes: 94.0;Erythrocyte progenitors: 48.1;Late spermatids: 42.6;Oligodendrocyte progenitor cells: 32.3;Oligodendrocytes: 50.6;Other brain neurons: 33.4;Retinal amacrine cells: 52.7;Retinal bipolar cells: 62.5;Retinal horizontal cells: 52.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 1.4;eosinophil: 1.1" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Myeloma: 58.3" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Fibroblasts, Breast - Adipocytes (Breast), Lung - Alveolar cells type 1, Minor Salivary Gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017598 Approved NA NA 160000 "Cluster 22: Eosinophils - Transcription" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 1: Enterocytes - Absorption and Digestion" 1 "HPA017598: " "unprognostic (3.73e-2)" "unprognostic (1.12e-2)" "potential prognostic favorable (2.71e-4)" "unprognostic (2.73e-3)" "unprognostic (9.68e-2)" "unprognostic (5.56e-3)" "unprognostic (4.38e-1)" "unprognostic (8.07e-2)" "unprognostic (2.24e-3)" "unprognostic (3.10e-2)" "potential prognostic favorable (6.95e-5)" "potential prognostic unfavorable (2.79e-4)" "unprognostic (1.55e-1)" "potential prognostic favorable (2.16e-5)" "unprognostic (1.40e-1)" "unprognostic (1.13e-2)" "unprognostic (3.09e-2)" "unprognostic (3.71e-1)" "unprognostic (1.22e-3)" "unprognostic (1.33e-1)" "unprognostic (1.54e-1)" "unprognostic (3.23e-1)" "unprognostic (1.89e-2)" "unprognostic (1.57e-1)" "unprognostic (7.14e-2)" "unprognostic (1.35e-1)" "unprognostic (4.00e-3)" MGAT4A "GnT-4a, GnT-Iva" ENSG00000071073 "Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A" Q9UM21 2 98619106-98731132 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 90.5" "Cell type enhanced" "Detected in many" "Microglia: 851.4;Neutrophil progenitors: 259.4;T-cells: 237.1" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 1092.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adrenal gland - Macrophages, Skin - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007608 Enhanced Approved "Golgi apparatus" "Secreted to blood" Enzyme NA NA "Cluster 11: T-cells - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 25: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" "Golgi apparatus" "HPA007608: " "unprognostic (2.90e-3)" "potential prognostic unfavorable (1.80e-4)" "unprognostic (9.38e-2)" "unprognostic (2.02e-1)" "unprognostic (9.14e-2)" "unprognostic (1.51e-1)" "unprognostic (7.72e-2)" "unprognostic (3.62e-2)" "unprognostic (2.27e-1)" "unprognostic (2.96e-2)" "potential prognostic favorable (4.38e-5)" "unprognostic (2.09e-3)" "unprognostic (3.12e-1)" "unprognostic (1.15e-2)" "unprognostic (1.53e-2)" "unprognostic (8.19e-3)" "unprognostic (2.99e-2)" "unprognostic (4.59e-2)" "unprognostic (2.35e-1)" "unprognostic (3.16e-1)" "unprognostic (3.28e-3)" "unprognostic (1.33e-1)" "unprognostic (2.26e-2)" "unprognostic (7.57e-2)" "unprognostic (1.58e-1)" "unprognostic (1.24e-1)" "unprognostic (1.42e-1)" "unprognostic (2.89e-2)" "unprognostic (1.69e-1)" "unprognostic (8.81e-2)" "potential prognostic unfavorable (1.30e-4)" MGAT4B GnT-Ivb ENSG00000161013 "Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B" Q9UQ53 5 179797597-179806952 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 281.1" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 19.6;Distal convoluted tubule cells: 14.7;Loop of henle epithelial cells: 17.5;Megakaryocytes: 18.5;Papillary tip epithelial cells: 20.4;Parietal cells: 15.9;Platelets: 60.4;Podocytes: 27.6;Proximal tubule cells: 15.0;Renal collecting duct principal cells: 17.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "eosinophil: 5.5" "Lineage enriched" "Detected in single" 6 "granulocytes: 5.5" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Skin - Keratinocyte (granular), Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012804, HPA052134" Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles,Cytosol" NA NA 25000 "Cluster 19: Eosinophils - Unknown function" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 29: Forebrain - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 98: Neurons - Neurotransmission & signaling" 2 Nucleoplasm "Golgi apparatus, Vesicles, Cytosol" "HPA012804: , HPA052134: " "unprognostic (2.86e-1)" "unprognostic (4.34e-3)" "unprognostic (5.19e-2)" "unprognostic (2.43e-2)" "unprognostic (2.17e-1)" "unprognostic (8.37e-2)" "unprognostic (3.65e-3)" "unprognostic (7.52e-2)" "unprognostic (5.23e-3)" "unprognostic (2.34e-2)" "unprognostic (4.13e-3)" "unprognostic (5.24e-3)" "unprognostic (2.73e-1)" "unprognostic (1.61e-3)" "unprognostic (1.80e-2)" "unprognostic (5.41e-2)" "unprognostic (8.40e-3)" "unprognostic (5.48e-2)" "unprognostic (2.88e-2)" "unprognostic (1.56e-1)" "unprognostic (1.82e-1)" "unprognostic (6.18e-3)" "unprognostic (1.30e-1)" "unprognostic (1.50e-1)" "unprognostic (1.61e-2)" "unprognostic (1.98e-1)" "unprognostic (2.41e-1)" "unprognostic (3.30e-1)" "unprognostic (4.32e-1)" "unprognostic (5.62e-2)" "unprognostic (2.53e-1)" MGAT4C HGNT-IV-H ENSG00000182050 "MGAT4 family member C" Q9UBM8 12 85955666-86838904 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 4.2;epididymis: 4.4;testis: 4.4;thyroid gland: 5.1" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 265.9;Astrocytes: 1383.1;Bergmann glia: 1075.4;Brain excitatory neurons: 377.4;Brain inhibitory neurons: 485.2;Corticotrophs: 241.6;Lactotrophs: 221.0;Leydig cells: 253.6;Other brain neurons: 374.4" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in single" 14 "Thyroid Carcinoma (TCGA): 7.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 1.4;Neuroblastoma: 1.3;testis cancer: 2.7" "Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Liver - Hepatic stellate cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016418 Approved Approved "Vesicles,Plasma membrane,Centriolar satellite" NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 28: Astrocytes - Homeostasis & neuron support" "Vesicles, Plasma membrane" "Centriolar satellite" "HPA016418: " "unprognostic (2.12e-3)" "unprognostic (1.34e-1)" MGAT4D GnT1IP ENSG00000205301 "MGAT4 family member D" A6NG13 4 140442262-140498377 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 37 "testis: 21.2" "Cell type enhanced" "Detected in some" "Early primary spermatocytes: 62.8;Early spermatids: 23.0;Ependymal cells: 33.0;Late primary spermatocytes: 184.1;Late spermatids: 51.7;Respiratory ciliated cells: 13.4" "Cell type enriched" "Detected in some" 10 "ependymal cell: 34.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA036523 Enhanced NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" "HPA036523: " MGAT5 "GNT-V, MGAT5A" ENSG00000152127 "Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase" Q09328 2 134119983-134454621 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "B-cells: 1122.8;Endometrial glandular cells: 1424.9;Podocytes: 1512.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010919 Approved "Intracellular and membrane" Enzyme NA NA 530000 "Cluster 22: Eosinophils - Transcription" "Cluster 35: Non-specific - Mixed function" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 16 "HPA010919: " "unprognostic (1.09e-1)" "unprognostic (2.68e-1)" "unprognostic (1.64e-1)" "unprognostic (7.22e-2)" "unprognostic (3.92e-1)" "unprognostic (8.70e-2)" "unprognostic (4.38e-1)" "unprognostic (1.99e-1)" "unprognostic (3.74e-1)" "unprognostic (6.33e-3)" "potential prognostic favorable (3.95e-6)" "unprognostic (8.00e-3)" "unprognostic (2.76e-2)" "unprognostic (1.35e-3)" "unprognostic (1.74e-1)" "unprognostic (1.95e-1)" "unprognostic (4.27e-3)" "unprognostic (1.36e-2)" "unprognostic (4.25e-2)" "unprognostic (5.21e-3)" "unprognostic (1.72e-3)" "unprognostic (2.59e-1)" "unprognostic (5.65e-2)" "unprognostic (1.94e-1)" "unprognostic (7.86e-3)" "unprognostic (1.66e-1)" "unprognostic (1.09e-1)" "unprognostic (8.20e-2)" "unprognostic (9.50e-2)" "unprognostic (1.73e-2)" "unprognostic (7.44e-2)" MGAT5B "FLJ25132, GnT-IX, GnT-VB" ENSG00000167889 "Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B" Q3V5L5 17 76868404-76950393 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 34 "brain: 39.4" "Cell type enhanced" "Detected in some" "Astrocytes: 15.7;Bergmann glia: 56.3;Brain excitatory neurons: 29.3;Brain inhibitory neurons: 38.2;Early spermatids: 15.4;Gonadotrophs: 12.6;Late spermatids: 18.8;Oocytes: 73.7;Other brain neurons: 12.8;Retinal amacrine cells: 30.5;Retinal ganglion cells: 19.3;Thyrotrophs: 11.2" "Cell type enhanced" "Detected in many" "upper-layer intratelencephalic: 117.4" "Cancer enhanced" "Detected in some" "Skin Cutaneous Melanoma (TCGA): 12.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Endothelial cells, Pituitary gland - Gonadotropes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011082 Approved "Nucleoplasm,Cytokinetic bridge,Mitotic spindle" Yes No "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 35: Neurons - Synaptic function & neurogenesis" 2 "Nucleoplasm, Mitotic spindle" "Cytokinetic bridge" "HPA011082: " "unprognostic (3.89e-1)" "unprognostic (1.33e-2)" "unprognostic (2.08e-2)" "unprognostic (5.10e-2)" "unprognostic (4.66e-2)" "unprognostic (2.21e-1)" MGLL "HU-K5, MAGL, MGL" ENSG00000074416 "Monoglyceride lipase" Q99685 3 127689062-128052190 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid degradation, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 1177.3;Cardiomyocytes: 1130.3;Esophageal apical cells: 1199.2;Platelets: 603.0" "Cell type enhanced" "Detected in all" "pericyte: 861.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 84.6" "Group enriched" "Detected in all" 13 "dendritic cells: 55.6;granulocytes: 37.0;monocytes: 84.6" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 1, Pancreas - Endothelial cells, Prostate - Smooth muscle cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011347, HPA011993, HPA011994" Enhanced Approved Vesicles NA NA 110000 "Cluster 25: Non-specific - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 4 Vesicles "HPA011347: , HPA011993: , HPA011994: " "unprognostic (7.87e-2)" "unprognostic (7.78e-2)" "unprognostic (5.43e-1)" "unprognostic (7.19e-3)" "unprognostic (2.92e-1)" "unprognostic (4.72e-2)" "unprognostic (7.50e-2)" "unprognostic (1.65e-1)" "unprognostic (1.25e-1)" "unprognostic (2.44e-1)" "unprognostic (8.62e-3)" "unprognostic (1.50e-1)" "unprognostic (1.79e-1)" "unprognostic (7.47e-2)" "unprognostic (5.85e-2)" "unprognostic (4.18e-2)" "unprognostic (3.98e-1)" "unprognostic (4.57e-2)" "unprognostic (1.97e-1)" "unprognostic (1.69e-1)" "unprognostic (1.56e-1)" "potential prognostic unfavorable (4.38e-4)" "unprognostic (8.29e-2)" "unprognostic (2.06e-2)" "unprognostic (1.00e-1)" "unprognostic (5.07e-2)" "unprognostic (1.03e-1)" "unprognostic (9.14e-2)" "unprognostic (2.62e-2)" "unprognostic (1.27e-1)" "unprognostic (7.82e-2)" MGME1 "bA504H3.4, C20orf72, DDK1" ENSG00000125871 "Mitochondrial genome maintenance exonuclease 1" Q9BQP7 20 17969018-17991122 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "Exonuclease, Hydrolase, Nuclease" "Disease variant, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 51.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040913 Approved Supported Mitochondria NA Yes "Cluster 41: Basophils - Unknown function" "Cluster 58: Skin - Keratinization" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 34 Mitochondria "HPA040913: " "unprognostic (1.32e-1)" "unprognostic (6.42e-2)" "unprognostic (3.87e-2)" "unprognostic (1.24e-1)" "unprognostic (2.05e-1)" "unprognostic (9.60e-2)" "unprognostic (4.04e-1)" "unprognostic (9.73e-2)" "unprognostic (5.09e-2)" "unprognostic (1.65e-1)" "unprognostic (6.31e-2)" "unprognostic (5.39e-2)" "potential prognostic unfavorable (5.42e-7)" "unprognostic (5.16e-2)" "unprognostic (3.99e-3)" "unprognostic (1.50e-1)" "unprognostic (1.00e-1)" "unprognostic (1.35e-1)" "unprognostic (1.91e-2)" "unprognostic (4.16e-3)" "unprognostic (1.37e-3)" "unprognostic (5.42e-2)" "unprognostic (9.03e-2)" "unprognostic (2.22e-2)" "unprognostic (7.43e-3)" "unprognostic (1.83e-1)" "unprognostic (1.94e-2)" "unprognostic (2.48e-2)" "unprognostic (2.06e-1)" MGMT ENSG00000170430 "O-6-methylguanine-DNA methyltransferase" P16455 10 129467190-129770983 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Methyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 125.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 649.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB002786, HPA032135, HPA032136, HPA069497, CAB069881" Supported Enhanced Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 49: Hindbrain - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 93: Hepatocytes - Bile production & excretion" 8 Nucleoplasm "CAB002786: , CAB069881: , HPA032135: , HPA032136: , HPA069497: " "unprognostic (8.50e-2)" "unprognostic (1.03e-1)" "unprognostic (3.38e-2)" "unprognostic (2.81e-2)" "unprognostic (1.73e-1)" "unprognostic (2.49e-1)" "potential prognostic unfavorable (5.26e-5)" "unprognostic (1.48e-1)" "unprognostic (3.12e-1)" "potential prognostic favorable (9.76e-4)" "potential prognostic favorable (7.55e-4)" "unprognostic (1.37e-1)" "unprognostic (5.48e-2)" "validated prognostic favorable (1.55e-4)" "validated prognostic favorable (9.77e-5)" "potential prognostic favorable (1.07e-4)" "unprognostic (5.08e-2)" "unprognostic (2.71e-1)" "unprognostic (7.58e-2)" "unprognostic (2.54e-1)" "unprognostic (7.63e-3)" "unprognostic (6.11e-2)" "unprognostic (1.07e-1)" "unprognostic (2.07e-1)" "unprognostic (1.14e-1)" "unprognostic (3.07e-2)" "unprognostic (2.09e-2)" "unprognostic (1.39e-1)" "unprognostic (3.05e-1)" "unprognostic (1.37e-1)" "unprognostic (1.53e-2)" MGP ENSG00000111341 "Matrix Gla protein" P08493 12 14880864-14885857 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Developmental protein" Deafness "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "blood vessel: 15727.7" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 10283.4;Breast myoepithelial cells: 2793.4;Breast secretory cells: 17168.2;Decidual stromal cells: 1719.0;Fibroblasts: 4591.4;Salivary acinar cells: 4296.0;Salivary myoepithelial cells: 2088.8;Smooth muscle cells: 1796.0;Vascular smooth muscle cells: 2107.6" "Group enriched" "Detected in many" 29 "endothelial cell: 241.5;fibroblast: 249.1;pericyte: 105.7;vascular associated smooth muscle cell: 238.8" "Cancer enriched" "Detected in all" 5 "Breast Invasive Carcinoma (TCGA): 5447.9" "Region enriched" "Detected in all" 6 "choroid plexus: 329.6" "Immune cell enriched" "Detected in single" 9 "plasmacytoid DC: 1.6" "Lineage enriched" "Detected in single" 9 "dendritic cells: 1.6" "Group enriched" "Detected in many" 4 "breast cancer: 636.8;Rhabdoid: 1570.8" "Adrenal gland - Fibroblasts, Heart muscle - Fibroblasts, Spleen - Smooth muscle cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013949 Approved "Secreted to blood" "Developmental protein" NA NA 20000000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 8: Immune cells - Immune response" "Cluster 5: Rhabdoid - Unknown function" "Cluster 108: Fibroblasts - ECM organization" 1 "HPA013949: " "unprognostic (1.96e-3)" "unprognostic (8.25e-3)" "unprognostic (2.58e-1)" "unprognostic (7.18e-2)" "unprognostic (1.75e-3)" "unprognostic (2.16e-2)" "unprognostic (9.54e-2)" "unprognostic (1.63e-1)" "unprognostic (1.34e-1)" "unprognostic (3.13e-2)" "unprognostic (3.00e-1)" "unprognostic (4.27e-3)" "potential prognostic unfavorable (2.03e-4)" "unprognostic (3.39e-2)" "unprognostic (2.63e-2)" "unprognostic (2.98e-3)" "unprognostic (2.88e-1)" "unprognostic (7.36e-2)" "unprognostic (2.27e-2)" "unprognostic (1.46e-1)" "unprognostic (7.13e-2)" "unprognostic (3.01e-1)" "unprognostic (5.56e-2)" "unprognostic (5.83e-2)" "unprognostic (5.43e-3)" "unprognostic (1.65e-1)" "unprognostic (3.22e-3)" "unprognostic (1.41e-2)" "unprognostic (8.39e-2)" "unprognostic (3.96e-2)" "unprognostic (3.09e-1)" MGRN1 "KIAA0544, RNF156" ENSG00000102858 "Mahogunin ring finger 1" O60291 16 4616493-4690974 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 293.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 16.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007653, HPA008033" Approved Supported "Endoplasmic reticulum,Vesicles" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 12 Vesicles "Endoplasmic reticulum" "HPA007653: , HPA008033: " "unprognostic (1.42e-2)" "unprognostic (1.66e-1)" "unprognostic (1.22e-1)" "unprognostic (1.16e-1)" "unprognostic (7.61e-2)" "unprognostic (2.44e-1)" "unprognostic (1.49e-1)" "unprognostic (1.24e-1)" "unprognostic (1.40e-1)" "unprognostic (1.54e-1)" "potential prognostic favorable (8.39e-4)" "unprognostic (1.46e-1)" "unprognostic (1.72e-2)" "unprognostic (1.21e-1)" "unprognostic (6.88e-2)" "unprognostic (4.46e-2)" "unprognostic (9.35e-3)" "unprognostic (3.76e-3)" "unprognostic (1.54e-1)" "unprognostic (3.12e-2)" "unprognostic (1.43e-1)" "unprognostic (7.70e-2)" "unprognostic (1.07e-3)" "unprognostic (2.82e-1)" "unprognostic (1.59e-1)" "unprognostic (4.44e-3)" "unprognostic (3.31e-1)" "unprognostic (2.52e-1)" "unprognostic (2.36e-1)" "unprognostic (7.51e-2)" "unprognostic (1.59e-2)" MGST1 "GST12, MGST-I, PMAN" ENSG00000008394 "Microsomal glutathione S-transferase 1" P10620 12 16347142-16609259 "Enzymes, Metabolic proteins, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 1028.7;adrenal gland: 1044.9;liver: 2898.8" "Cell type enhanced" "Detected in many" "Adipocytes: 1314.2;Alveolar cells type 1: 1350.9;Alveolar cells type 2: 2177.9;Endometrial glandular cells: 1213.7;Hepatocytes: 5068.2;Respiratory secretory cells: 1122.4;Transitional alveolar cells: 1536.8;Urothelial cells: 1075.1" "Cell type enhanced" "Detected in all" "astrocyte: 527.2;Bergmann glia: 723.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 171.3;myeloid DC: 124.0" "Group enriched" "Detected in many" 13 "dendritic cells: 124.0;monocytes: 171.3" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Colon - Macrophages, Kidney - Proximal tubular cells, Minor Salivary Gland - Minor salivary glandular cells, Skin - Sebaceous gland cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044840 Enhanced Approved "Endoplasmic reticulum,Mitochondria" NA NA 34000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 76: Non-specific - Metabolism" "Cluster 46: Brainstem - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 81: Alveolar cells - Lung function" 11 Mitochondria "Endoplasmic reticulum" "HPA044840: " "unprognostic (3.26e-1)" "unprognostic (3.06e-2)" "unprognostic (6.44e-2)" "unprognostic (9.71e-3)" "unprognostic (8.55e-2)" "unprognostic (3.35e-2)" "unprognostic (1.84e-3)" "unprognostic (3.46e-1)" "unprognostic (1.11e-1)" "unprognostic (1.66e-1)" "unprognostic (3.26e-2)" "unprognostic (1.89e-2)" "unprognostic (3.89e-3)" "unprognostic (1.09e-1)" "unprognostic (5.80e-2)" "unprognostic (1.64e-2)" "unprognostic (3.74e-1)" "unprognostic (9.85e-3)" "unprognostic (6.90e-2)" "unprognostic (8.26e-2)" "unprognostic (2.65e-1)" "unprognostic (4.02e-3)" "potential prognostic unfavorable (4.87e-4)" "unprognostic (2.51e-1)" "unprognostic (1.79e-1)" "unprognostic (2.93e-2)" "unprognostic (6.35e-2)" "unprognostic (2.10e-1)" "unprognostic (4.83e-1)" "unprognostic (8.81e-3)" "unprognostic (1.57e-3)" MGST2 MGST-II ENSG00000085871 "Microsomal glutathione S-transferase 2" Q99735 4 139665768-139740745 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Leukotriene biosynthesis, Lipid metabolism" "Lyase, Oxidoreductase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 366.8" "Cell type enhanced" "Detected in many" "Breast lactating cells: 490.9;Esophageal apical cells: 1055.4;Esophageal basal cells: 479.5;Esophageal suprabasal cells: 847.6;Gastric progenitor cells: 775.4;Hepatocytes: 513.1;Hofbauer cells: 691.8" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 158.6;endothelial cell: 209.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 195.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Heart muscle - Cardiomyocytes, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA010690, HPA010707" Enhanced Uncertain "Endoplasmic reticulum,Cytosol" NA NA 11000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 85: Squamous epithelial cells - Keratinization" 22 Cytosol "Endoplasmic reticulum" "HPA010690: , HPA010707: " "unprognostic (6.09e-2)" "unprognostic (1.77e-2)" "unprognostic (4.33e-2)" "unprognostic (1.92e-1)" "unprognostic (2.07e-3)" "unprognostic (3.07e-1)" "unprognostic (2.04e-2)" "unprognostic (5.70e-2)" "unprognostic (1.32e-1)" "unprognostic (2.30e-1)" "validated prognostic favorable (2.25e-10)" "validated prognostic favorable (3.05e-5)" "potential prognostic favorable (6.42e-4)" "unprognostic (1.67e-3)" "unprognostic (9.07e-3)" "unprognostic (9.83e-2)" "unprognostic (1.05e-1)" "unprognostic (1.46e-1)" "unprognostic (1.83e-1)" "unprognostic (7.77e-2)" "unprognostic (3.89e-2)" "unprognostic (1.36e-1)" "unprognostic (2.99e-1)" "unprognostic (2.14e-1)" "unprognostic (2.23e-1)" "unprognostic (1.17e-1)" "unprognostic (1.03e-1)" "unprognostic (3.70e-1)" "unprognostic (5.75e-1)" "unprognostic (7.20e-2)" "unprognostic (1.17e-2)" MGST3 GST-III ENSG00000143198 "Microsomal glutathione S-transferase 3" O14880 1 165631213-165661796 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" "Lyase, Oxidoreductase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 2622.1;Epididymal principal cells: 1621.2;Extravillous trophoblasts: 1727.0;Migrating cytotrophoblasts: 1617.4;Syncytiotrophoblasts: 2677.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053311, HPA077929" Enhanced Approved Nucleoplasm NA NA 330000 "Cluster 33: Non-specific - ATP binding" "Cluster 52: Non-specific - Cellular respiration" "Cluster 45: Non-specific - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 107 Nucleoplasm "HPA053311: , HPA077929: " "unprognostic (9.03e-3)" "unprognostic (1.08e-1)" "unprognostic (2.56e-1)" "unprognostic (2.77e-2)" "unprognostic (5.78e-3)" "unprognostic (3.62e-2)" "unprognostic (9.73e-2)" "unprognostic (2.73e-1)" "unprognostic (1.16e-2)" "unprognostic (1.28e-2)" "potential prognostic favorable (9.36e-5)" "unprognostic (4.66e-2)" "unprognostic (1.55e-1)" "unprognostic (8.46e-2)" "unprognostic (2.57e-1)" "unprognostic (1.74e-2)" "unprognostic (5.84e-2)" "unprognostic (8.28e-3)" "unprognostic (9.82e-2)" "unprognostic (2.52e-1)" "unprognostic (1.31e-1)" "unprognostic (1.02e-1)" "unprognostic (6.98e-2)" "unprognostic (6.63e-2)" "unprognostic (5.68e-2)" "unprognostic (2.18e-2)" "unprognostic (2.16e-1)" "unprognostic (2.71e-2)" "unprognostic (1.59e-1)" "unprognostic (1.59e-1)" "unprognostic (2.11e-1)" MIA CD-RAP ENSG00000261857 "MIA SH3 domain containing" Q16674 19 40771648-40777490 "Cancer-related genes, Predicted secreted proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 54.1;pituitary gland: 73.8;salivary gland: 40.7;stomach 1: 61.9" "Group enriched" "Detected in some" 5 "Breast myoepithelial cells: 162.7;Breast secretory cells: 138.9;Foveolar cells: 68.0;Gastric chief cells: 91.7;Melanocytes: 109.6;Mucous neck cells: 148.8;Schwann cells: 81.0;Submucosal glandular cells: 91.4" "Cell type enhanced" "Detected in some" "leukocyte: 2.4" "Cancer enriched" "Detected in many" 8 "Skin Cutaneous Melanoma (TCGA): 1375.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "neutrophil: 2.7" "Lineage enriched" "Detected in single" 9 "granulocytes: 2.7" "Cancer enriched" "Detected in many" 5 "skin cancer: 473.9" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Region enriched" "Detected in single" 27 "olfactory bulb: 25.9" HPA042369 Approved "Secreted to blood" "Growth factor" NA NA 8270000 19000 "Cluster 35: Neutrophils - Protein binding" "Cluster 60: Stomach - Digestion" "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 97: Non-specific - Cellular respiration" "HPA042369: " "unprognostic (1.84e-1)" "potential prognostic favorable (2.88e-4)" "unprognostic (2.23e-1)" "unprognostic (6.61e-2)" "unprognostic (1.50e-1)" "unprognostic (1.16e-1)" "unprognostic (2.05e-1)" "unprognostic (1.72e-1)" "unprognostic (6.52e-2)" "potential prognostic unfavorable (7.89e-7)" "unprognostic (2.66e-2)" "unprognostic (4.65e-3)" "unprognostic (3.29e-1)" "unprognostic (5.36e-2)" "unprognostic (2.48e-2)" "unprognostic (9.23e-3)" "unprognostic (1.20e-1)" "unprognostic (4.35e-1)" "unprognostic (8.32e-2)" "unprognostic (1.55e-2)" "unprognostic (1.29e-1)" "unprognostic (3.59e-1)" "unprognostic (1.58e-1)" "unprognostic (1.73e-1)" "unprognostic (4.01e-2)" "unprognostic (1.97e-1)" "unprognostic (6.32e-2)" "unprognostic (1.07e-1)" MIA2 "cTAGE-5A, cTAGE-5B, cTAGE-5C, cTAGE-5D, CTAGE5, FLJ22404, MEA6, MGEA, MGEA11, MGEA6, TALI" ENSG00000150527 "MIA SH3 domain ER export factor 2" Q96PC5 14 39230231-39388513 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 126.3" "Cell type enhanced" "Detected in all" "Enterocytes: 380.0;Myonuclei: 435.9;Proximal tubule cells: 367.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "choroid plexus: 135.6" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Kidney - Proximal tubular cells, Skeletal muscle - Skeletal myocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000387, HPA000922, HPA054066, HPA055459" Approved Supported "Endoplasmic reticulum" "Intracellular and membrane" "No annotated function" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 76: Non-specific - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 13 "Endoplasmic reticulum" "HPA000387: , HPA000922: , HPA054066: , HPA055459: " "unprognostic (9.78e-3)" "unprognostic (2.08e-2)" "unprognostic (3.96e-2)" "unprognostic (2.32e-1)" "unprognostic (1.10e-1)" "unprognostic (2.24e-2)" "unprognostic (6.74e-2)" "unprognostic (4.49e-2)" "unprognostic (7.35e-2)" "validated prognostic favorable (1.68e-8)" "validated prognostic favorable (2.03e-4)" "unprognostic (9.17e-2)" "unprognostic (2.79e-1)" "unprognostic (1.38e-1)" "unprognostic (4.33e-2)" "unprognostic (1.05e-1)" "unprognostic (5.97e-2)" "unprognostic (3.73e-1)" "unprognostic (9.90e-2)" "unprognostic (3.39e-2)" "unprognostic (1.60e-1)" "unprognostic (5.71e-3)" "unprognostic (1.36e-1)" "unprognostic (6.51e-2)" "potential prognostic unfavorable (5.69e-4)" "unprognostic (1.73e-1)" "unprognostic (3.28e-1)" "unprognostic (1.71e-1)" "unprognostic (5.16e-2)" "unprognostic (2.37e-1)" MIA3 "FLJ39207, KIAA0268, TANGO, TANGO1, UNQ6077" ENSG00000154305 "MIA SH3 domain ER export factor 3" Q5JRA6 1 222618097-222668007 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "ER-Golgi transport, Exocytosis, Protein transport, Transport" "Deafness, Diabetes mellitus, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Prostatic glandular cells: 304.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055922, HPA056816" Supported Enhanced Vesicles NA NA 4400000 "Cluster 35: Neutrophils - Protein binding" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 31: Non-specific - Transcription" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 70: Intestinal goblet cells - Mucin production" 26 Vesicles "HPA055922: , HPA056816: " "unprognostic (5.23e-2)" "unprognostic (2.24e-1)" "unprognostic (1.98e-1)" "unprognostic (6.98e-2)" "unprognostic (1.22e-1)" "unprognostic (2.94e-2)" "unprognostic (5.70e-2)" "unprognostic (4.05e-1)" "unprognostic (5.09e-2)" "unprognostic (4.07e-2)" "potential prognostic favorable (2.10e-4)" "unprognostic (3.68e-1)" "unprognostic (1.02e-2)" "unprognostic (5.41e-3)" "potential prognostic favorable (4.57e-4)" "unprognostic (1.19e-1)" "unprognostic (1.66e-1)" "unprognostic (2.36e-1)" "unprognostic (6.07e-2)" "unprognostic (1.88e-1)" "unprognostic (9.98e-2)" "unprognostic (3.74e-2)" "unprognostic (1.12e-1)" "unprognostic (3.72e-2)" "unprognostic (2.48e-1)" "unprognostic (2.16e-2)" "unprognostic (1.11e-1)" "unprognostic (3.24e-1)" "unprognostic (4.19e-1)" "unprognostic (1.77e-2)" "unprognostic (2.47e-1)" MIB1 "DIP-1, KIAA1323, MIB, ZZANK2, ZZZ6" ENSG00000101752 "MIB E3 ubiquitin protein ligase 1" Q86YT6 18 21704957-21870953 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Notch signaling pathway, Ubl conjugation pathway" Transferase "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 2576.9;Myonuclei: 980.3;Podocytes: 526.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019100, CAB037044, HPA067539" Approved Approved "Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Centriolar satellite,Basal body" Yes NA "Cluster 41: Basophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 44: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 50 "Microtubules, Primary cilium" "Cytokinetic bridge, Mitotic spindle, Centriolar satellite, Basal body" "CAB037044: , HPA019100: , HPA067539: " "unprognostic (4.48e-2)" "unprognostic (2.36e-1)" "unprognostic (1.48e-1)" "unprognostic (6.16e-3)" "unprognostic (3.78e-2)" "unprognostic (1.48e-1)" "unprognostic (4.11e-2)" "potential prognostic favorable (7.18e-4)" "unprognostic (5.01e-2)" "unprognostic (1.14e-1)" "potential prognostic favorable (3.18e-4)" "unprognostic (3.54e-2)" "unprognostic (4.29e-2)" "unprognostic (1.52e-2)" "unprognostic (3.09e-2)" "unprognostic (1.50e-1)" "unprognostic (2.06e-2)" "unprognostic (2.79e-1)" "unprognostic (1.16e-2)" "unprognostic (8.92e-2)" "unprognostic (1.10e-2)" "unprognostic (3.80e-2)" "unprognostic (5.02e-2)" "unprognostic (3.54e-2)" "unprognostic (2.25e-1)" "unprognostic (4.68e-2)" "unprognostic (4.62e-2)" "unprognostic (3.69e-2)" "unprognostic (3.81e-1)" "unprognostic (2.00e-2)" "unprognostic (1.56e-1)" MIB2 "FLJ39787, skeletrophin, ZZANK1, ZZZ5" ENSG00000197530 "MIB E3 ubiquitin protein ligase 2" Q96AX9 1 1615454-1630605 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Notch signaling pathway, Ubl conjugation pathway" "Actin-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 46.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 126.4;Esophageal basal cells: 217.0;Esophageal suprabasal cells: 150.3;Gastric progenitor cells: 153.8;Late spermatids: 408.6;Suprabasal keratinocytes: 108.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Stomach Adenocarcinoma (TCGA): 25.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068322 Enhanced NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 24: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 26: Keratinocytes - Keratinization" 10 "HPA068322: " "unprognostic (8.95e-2)" "unprognostic (1.57e-1)" "unprognostic (1.62e-1)" "unprognostic (3.64e-2)" "unprognostic (1.72e-1)" "potential prognostic unfavorable (7.55e-4)" "unprognostic (1.75e-1)" "unprognostic (9.83e-3)" "unprognostic (8.69e-3)" "unprognostic (3.34e-1)" "potential prognostic favorable (4.17e-4)" "unprognostic (4.60e-2)" "unprognostic (8.90e-3)" "unprognostic (3.51e-1)" "unprognostic (3.80e-2)" "unprognostic (2.75e-1)" "unprognostic (9.77e-3)" "unprognostic (1.46e-1)" "unprognostic (6.10e-3)" "unprognostic (1.39e-2)" "unprognostic (2.45e-1)" "unprognostic (1.86e-1)" "unprognostic (2.81e-1)" "potential prognostic favorable (5.86e-4)" "unprognostic (3.47e-3)" "unprognostic (1.89e-1)" "unprognostic (1.16e-2)" "unprognostic (6.57e-2)" "unprognostic (3.33e-2)" MICA PERB11.1 ENSG00000204520 "MHC class I polypeptide-related sequence A" 6 31399784-31415315 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 23.6;Loop of henle epithelial cells: 30.2;Paneth cells: 23.2;Podocytes: 59.1;Proximal tubule cells: 23.0;Renal collecting duct principal cells: 24.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 9: Non-specific - Receptor signaling" "Cluster 72: Neuronal - Signal transduction" "Cluster 105: Non-specific - Mixed function" 1 "unprognostic (1.03e-1)" "unprognostic (1.29e-2)" "unprognostic (4.17e-1)" "unprognostic (4.56e-2)" "unprognostic (4.27e-2)" "unprognostic (2.55e-3)" "unprognostic (1.43e-1)" "potential prognostic unfavorable (5.32e-4)" "potential prognostic favorable (2.51e-4)" "unprognostic (3.87e-2)" "unprognostic (1.50e-1)" "unprognostic (1.02e-1)" "unprognostic (1.90e-2)" "unprognostic (7.38e-3)" "unprognostic (3.71e-2)" "unprognostic (4.63e-3)" "unprognostic (3.83e-1)" "unprognostic (1.32e-1)" "unprognostic (8.54e-2)" "unprognostic (6.98e-2)" "unprognostic (3.14e-2)" "unprognostic (4.01e-2)" "unprognostic (5.83e-3)" "unprognostic (1.99e-2)" "unprognostic (1.48e-1)" "unprognostic (7.15e-2)" "unprognostic (1.92e-1)" "unprognostic (1.83e-1)" "unprognostic (1.44e-2)" "unprognostic (1.68e-1)" "unprognostic (4.87e-1)" MICAL1 "DKFZp434B1517, FLJ11937, FLJ21739, MICAL, NICAL" ENSG00000135596 "Microtubule associated monooxygenase, calponin and LIM domain containing 1" Q8TDZ2 6 109444062-109465968 "Enzymes, Predicted intracellular proteins" "Actin-binding, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "cDC: 57.9;Decidual stromal cells: 62.1;Goblet cells: 57.8;Neutrophil progenitors: 85.3;Neutrophils: 86.3;pDCs: 59.8;Smooth muscle cells: 66.6;Vascular smooth muscle cells: 58.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA030175, HPA030176, HPA030178" Approved Approved "Nucleoplasm,Plasma membrane,Primary cilium,Basal body,Cytosol" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 30: White matter - Myelination" "Cluster 35: RS4;11 - Unknown function" "Cluster 62: Smooth muscle cells - Muscle contraction" 7 "Nucleoplasm, Primary cilium, Cytosol" "Plasma membrane, Basal body" "HPA030175: , HPA030176: , HPA030178: " "unprognostic (1.15e-1)" "unprognostic (4.34e-2)" "unprognostic (1.44e-1)" "unprognostic (1.14e-2)" "unprognostic (7.31e-2)" "unprognostic (6.25e-2)" "unprognostic (2.34e-1)" "unprognostic (4.74e-3)" "unprognostic (1.46e-2)" "unprognostic (1.15e-1)" "potential prognostic unfavorable (7.72e-4)" "unprognostic (3.29e-1)" "unprognostic (2.27e-2)" "unprognostic (9.54e-3)" "unprognostic (1.29e-1)" "unprognostic (3.94e-3)" "unprognostic (2.76e-1)" "unprognostic (1.51e-1)" "unprognostic (3.65e-1)" "unprognostic (1.07e-2)" "unprognostic (6.58e-2)" "potential prognostic favorable (3.16e-6)" "unprognostic (2.90e-2)" "unprognostic (1.96e-1)" "unprognostic (2.47e-2)" "unprognostic (1.91e-1)" "unprognostic (1.06e-1)" "unprognostic (1.59e-1)" "unprognostic (1.54e-1)" "unprognostic (1.75e-1)" "unprognostic (1.05e-1)" MICAL2 "FLJ14966, KIAA0750, MICALCL" ENSG00000133816 "Microtubule associated monooxygenase, calponin and LIM domain containing 2" O94851 11 12094008-12359144 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Actin-binding, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 138.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 424.6;Alveolar cells type 2: 475.3;Choroid plexus epithelial cells: 659.1;Colonocytes: 370.5;Late spermatids: 409.3;Neutrophils: 321.3;Peritubular myoid cells: 311.3;Sertoli cells: 487.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 11.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Adrenal gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030437, HPA039895, HPA040438" Approved Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 27: Cerebellum - Synaptic function" "Cluster 16: Non-specific - Transcription" "Cluster 72: Neuronal - Signal transduction" "Cluster 24: Neutrophils - Innate immunity signal integration" 16 Cytosol "Nucleoplasm, Plasma membrane" "HPA030437: , HPA039895: , HPA040438: " "unprognostic (1.16e-2)" "unprognostic (1.57e-1)" "unprognostic (1.70e-1)" "unprognostic (1.76e-2)" "unprognostic (1.37e-1)" "unprognostic (2.49e-2)" "unprognostic (1.54e-2)" "unprognostic (1.35e-1)" "unprognostic (1.01e-1)" "unprognostic (1.34e-3)" "unprognostic (4.59e-3)" "unprognostic (5.63e-2)" "unprognostic (2.86e-1)" "unprognostic (1.51e-1)" "unprognostic (6.35e-3)" "unprognostic (5.51e-2)" "unprognostic (1.81e-2)" "unprognostic (3.81e-3)" "unprognostic (6.91e-2)" "unprognostic (8.99e-2)" "potential prognostic unfavorable (3.55e-5)" "unprognostic (6.60e-3)" "unprognostic (1.37e-1)" "unprognostic (2.58e-1)" "unprognostic (4.89e-3)" "unprognostic (1.20e-2)" "unprognostic (1.10e-1)" "unprognostic (1.92e-1)" "unprognostic (3.55e-1)" "unprognostic (2.51e-1)" "unprognostic (7.05e-2)" MICAL3 KIAA0819 ENSG00000243156 "Microtubule associated monooxygenase, calponin and LIM domain containing 3" Q7RTP6 22 17787649-18024561 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Exocytosis" "Actin-binding, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 429.5;Choroid plexus epithelial cells: 439.4;Myonuclei: 337.3;Oligodendrocytes: 359.7;Proximal tubule cells: 365.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "basophil: 11.2" "Lineage enriched" "Detected in many" 4 "granulocytes: 11.2" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Colon - Enteric glia cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000639, HPA003421, HPA034882" Approved Supported "Nucleoplasm,Plasma membrane,Midbody ring,Cytosol" Yes No "Cluster 32: Basophils - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 15: Non-specific - Transcription" "Cluster 69: Skin cancer - ECM organization" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 6 "Nucleoplasm, Midbody ring" "Plasma membrane, Cytosol" "HPA000639: , HPA003421: , HPA034882: " "unprognostic (2.56e-1)" "unprognostic (8.71e-2)" "unprognostic (2.78e-2)" "unprognostic (2.43e-2)" "unprognostic (1.03e-1)" "unprognostic (2.73e-1)" "unprognostic (6.68e-2)" "potential prognostic favorable (7.74e-5)" "unprognostic (2.63e-1)" "unprognostic (1.59e-2)" "potential prognostic favorable (2.53e-4)" "unprognostic (1.85e-2)" "unprognostic (2.52e-2)" "unprognostic (9.58e-2)" "unprognostic (3.29e-2)" "unprognostic (6.30e-3)" "unprognostic (1.84e-2)" "unprognostic (1.07e-1)" "unprognostic (1.89e-2)" "unprognostic (1.22e-1)" "unprognostic (1.49e-1)" "unprognostic (2.24e-1)" "unprognostic (1.14e-2)" "unprognostic (3.79e-1)" "unprognostic (1.99e-3)" "unprognostic (1.59e-1)" "unprognostic (8.41e-2)" "unprognostic (1.19e-1)" "unprognostic (4.18e-1)" "unprognostic (1.68e-1)" "unprognostic (4.69e-2)" MICALL1 "KIAA1668, MICAL-L1, MIRAB13" ENSG00000100139 "MICAL like 1" Q8N3F8 22 37905657-37942822 "Plasma proteins, Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 67.3;Esophageal apical cells: 84.4;Esophageal suprabasal cells: 80.4;Migrating cytotrophoblasts: 63.1;Parietal cells: 93.7;Syncytiotrophoblasts: 69.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Colon - Smooth muscle cells, Prostate - Smooth muscle cells, Skin - Keratinocyte (granular), Stomach - Parietal cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043480, HPA051956" Approved Supported "Cell Junctions,Centriolar satellite,Cytosol" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 28 "Cell Junctions, Centriolar satellite, Cytosol" "HPA043480: , HPA051956: " "unprognostic (2.88e-1)" "unprognostic (7.26e-2)" "unprognostic (2.81e-1)" "unprognostic (1.77e-1)" "unprognostic (5.76e-2)" "unprognostic (1.88e-1)" "unprognostic (3.92e-1)" "unprognostic (1.57e-1)" "unprognostic (9.41e-2)" "unprognostic (1.20e-2)" "unprognostic (2.20e-3)" "unprognostic (2.19e-2)" "unprognostic (3.49e-1)" "potential prognostic unfavorable (1.05e-4)" "unprognostic (7.05e-2)" "unprognostic (1.92e-2)" "unprognostic (5.56e-2)" "unprognostic (1.20e-1)" "unprognostic (2.55e-1)" "unprognostic (2.07e-1)" "unprognostic (1.63e-1)" "unprognostic (3.30e-3)" "potential prognostic unfavorable (6.89e-4)" "unprognostic (8.71e-2)" "unprognostic (6.81e-2)" "unprognostic (4.83e-3)" "unprognostic (7.28e-2)" "unprognostic (2.05e-2)" "unprognostic (1.68e-1)" "unprognostic (1.08e-2)" "unprognostic (4.34e-2)" MICALL2 "FLJ23471, JRAB, MGC46023, MICAL-L2" ENSG00000164877 "MICAL like 2" Q8IY33 7 1428465-1459470 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 134.8;Bergmann glia: 158.0;Colonocytes: 106.5;Enterocytes: 114.1;Foveolar cells: 180.0;Goblet cells: 82.5;Oocytes: 128.9" "Cell type enhanced" "Detected in all" "astrocyte: 157.1;Bergmann glia: 159.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 33.8" "Adipose subcutaneous - Adipose progenitor cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA025695 Enhanced NA NA "Cluster 77: Intestine - Digestion" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 67: Non-specific - Unknown function" "Cluster 68: Foveolar cells - Mucosal defense" 8 "HPA025695: " "unprognostic (5.07e-2)" "unprognostic (1.58e-1)" "unprognostic (1.27e-1)" "unprognostic (2.34e-1)" "unprognostic (3.10e-1)" "unprognostic (8.15e-2)" "unprognostic (1.02e-2)" "unprognostic (3.40e-3)" "unprognostic (1.20e-2)" "unprognostic (3.40e-1)" "unprognostic (3.80e-3)" "unprognostic (4.29e-2)" "unprognostic (2.70e-1)" "unprognostic (1.71e-2)" "unprognostic (1.77e-1)" "unprognostic (1.42e-2)" "unprognostic (3.08e-1)" "unprognostic (1.50e-2)" "unprognostic (5.56e-2)" "unprognostic (5.85e-2)" "unprognostic (1.76e-1)" "unprognostic (1.02e-1)" "unprognostic (2.76e-2)" "unprognostic (1.88e-1)" "unprognostic (1.20e-1)" "unprognostic (4.27e-2)" "unprognostic (8.41e-2)" "unprognostic (1.85e-1)" "unprognostic (8.44e-2)" "unprognostic (1.91e-1)" "unprognostic (4.36e-2)" MICB PERB11.2 ENSG00000204516 "MHC class I polypeptide-related sequence B" Q29980 6 31494881-31511124 "Disease related genes, Predicted membrane proteins" "Adaptive immunity, Cytolysis, Host-virus interaction, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 9.4" "Cell type enhanced" "Detected in some" "B-cells: 1.7;Brain excitatory neurons: 1.6;Kupffer cells: 1.0;Microglia: 7.2;monocytes: 1.2;NK-cells: 1.9;Papillary tip epithelial cells: 1.6" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 9.4;leukocyte: 15.2" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" HPA064618 Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 5: Spleen - Immune response" "Cluster 20: Myeloma - Immune response" "Cluster 102: Non-specific - Mixed function" 4 "Golgi apparatus, Plasma membrane" Nucleoplasm "HPA064618: " "unprognostic (2.80e-1)" "unprognostic (3.56e-1)" "unprognostic (4.64e-1)" "unprognostic (3.40e-1)" "unprognostic (3.67e-1)" "unprognostic (2.12e-2)" "unprognostic (8.80e-2)" "unprognostic (1.87e-1)" "unprognostic (2.20e-1)" "unprognostic (1.25e-1)" "potential prognostic unfavorable (9.69e-4)" "unprognostic (1.03e-1)" "unprognostic (1.41e-3)" MICOS10 "C1orf151, FLJ36999, Mic10, MINOS1, MIO10, RP5-1056L3.2" ENSG00000173436 "Mitochondrial contact site and cristae organizing system subunit 10" Q5TGZ0 1 19484403-19629821 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 344.0;Early spermatids: 242.9;Enteric stem cells: 262.7;Enteric transient amplifying cells: 358.2;Enterocytes: 269.9;Epididymal clear cells: 251.1;Epididymal efferent duct absorptive cells: 222.0;Epididymal efferent duct ciliated cells: 264.4;Gastric progenitor cells: 593.4;Late spermatids: 260.6;Microglia: 380.7;Parietal cells: 878.6" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 445.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059930 Enhanced Supported Mitochondria NA NA 28000 "Cluster 25: Non-specific - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 1: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 15: Non-specific - Protein processing" 8 Mitochondria "HPA059930: " "unprognostic (4.37e-2)" "unprognostic (1.66e-1)" "unprognostic (1.46e-1)" "unprognostic (7.40e-2)" "unprognostic (2.66e-2)" "unprognostic (8.58e-2)" "unprognostic (2.17e-1)" "unprognostic (4.83e-2)" "unprognostic (6.02e-3)" "validated prognostic favorable (4.15e-8)" "validated prognostic favorable (1.52e-4)" "potential prognostic favorable (4.11e-6)" "unprognostic (4.26e-2)" "unprognostic (6.86e-2)" "unprognostic (3.59e-2)" "unprognostic (9.28e-3)" "unprognostic (2.39e-1)" "unprognostic (9.84e-2)" "unprognostic (5.27e-2)" "unprognostic (4.16e-2)" "unprognostic (1.02e-1)" "unprognostic (7.88e-2)" "unprognostic (8.42e-3)" "unprognostic (3.28e-1)" "unprognostic (7.68e-2)" "unprognostic (1.20e-1)" "unprognostic (5.22e-2)" "unprognostic (9.79e-2)" "unprognostic (1.25e-1)" MICOS13 "C19orf70, MIC12, MIC13, P117, QIL1" ENSG00000174917 "Mitochondrial contact site and cristae organizing system subunit 13" Q5XKP0 19 5678421-5680516 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 7 "Late spermatids: 6711.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042672 Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 45: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 14 Mitochondria Nucleoplasm "HPA042672: " "unprognostic (2.72e-1)" "unprognostic (1.53e-1)" "unprognostic (1.34e-2)" "unprognostic (2.08e-1)" "unprognostic (8.31e-2)" "unprognostic (1.83e-1)" "unprognostic (1.74e-1)" "unprognostic (8.56e-2)" "unprognostic (9.72e-2)" "unprognostic (8.30e-3)" "unprognostic (7.54e-2)" "unprognostic (6.60e-3)" "unprognostic (7.45e-2)" "unprognostic (1.41e-1)" "unprognostic (5.83e-2)" "unprognostic (3.35e-2)" "unprognostic (2.79e-1)" "unprognostic (4.09e-1)" "unprognostic (1.97e-1)" "unprognostic (9.43e-2)" "unprognostic (4.24e-1)" "unprognostic (3.48e-1)" "unprognostic (2.39e-2)" "unprognostic (2.33e-1)" "unprognostic (1.58e-2)" "unprognostic (2.10e-1)" "unprognostic (2.12e-2)" "unprognostic (8.55e-2)" "unprognostic (1.57e-2)" MICU1 "CALC, CBARA1, EFHA3, FLJ12684" ENSG00000107745 "Mitochondrial calcium uptake 1" Q9BPX6 10 72367340-72626131 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Calcium transport, Ion transport, Transport" "Allergen, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Myonuclei: 860.0;Neutrophils: 623.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037480, HPA057525" Approved Supported Mitochondria NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 35: Non-specific - DNA binding" "Cluster 52: Non-specific - Mitochondria" "Cluster 55: Myocytes - Oxidative muscle function" 9 Mitochondria "HPA037480: , HPA057525: " "unprognostic (5.76e-3)" "unprognostic (1.44e-2)" "unprognostic (2.13e-1)" "unprognostic (1.98e-1)" "potential prognostic unfavorable (7.42e-4)" "unprognostic (8.37e-2)" "potential prognostic favorable (2.84e-4)" "unprognostic (1.58e-1)" "unprognostic (1.56e-2)" "validated prognostic favorable (1.32e-10)" "validated prognostic favorable (1.62e-4)" "unprognostic (6.71e-3)" "unprognostic (1.61e-1)" "unprognostic (5.58e-3)" "unprognostic (2.49e-1)" "unprognostic (1.72e-1)" "unprognostic (1.80e-3)" "unprognostic (2.20e-2)" "unprognostic (3.90e-1)" "unprognostic (2.44e-1)" "unprognostic (7.78e-2)" "unprognostic (2.08e-1)" "unprognostic (1.89e-1)" "unprognostic (4.71e-2)" "unprognostic (6.35e-2)" "unprognostic (4.55e-2)" "unprognostic (1.28e-1)" "unprognostic (1.78e-1)" "unprognostic (6.96e-2)" "unprognostic (1.29e-1)" MICU2 EFHA1 ENSG00000165487 "Mitochondrial calcium uptake 2" Q8IYU8 13 21492691-21604181 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045511, HPA058790" Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 76: Non-specific - Metabolism" "Cluster 31: Non-specific - Transcription" "Cluster 19: Non-specific - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 17 Nucleoplasm Mitochondria "HPA045511: , HPA058790: " "unprognostic (3.25e-1)" "unprognostic (1.70e-2)" "unprognostic (3.30e-2)" "unprognostic (1.57e-1)" "unprognostic (1.33e-2)" "unprognostic (2.05e-1)" "unprognostic (7.09e-2)" "unprognostic (1.11e-2)" "unprognostic (7.86e-2)" "potential prognostic favorable (8.30e-11)" "unprognostic (2.94e-3)" "unprognostic (1.22e-3)" "unprognostic (4.04e-3)" "unprognostic (1.88e-2)" "unprognostic (6.49e-2)" "unprognostic (1.07e-1)" "unprognostic (2.01e-1)" "unprognostic (1.44e-3)" "unprognostic (2.32e-2)" "unprognostic (1.70e-1)" "unprognostic (6.00e-2)" "unprognostic (1.64e-1)" "unprognostic (1.46e-1)" "unprognostic (1.56e-1)" "unprognostic (4.86e-3)" "unprognostic (3.15e-2)" "unprognostic (3.11e-1)" "unprognostic (2.37e-1)" "unprognostic (1.44e-1)" MICU3 "DKFZp313A0139, EFHA2" ENSG00000155970 "Mitochondrial calcium uptake family member 3" Q86XE3 8 17027238-17122642 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.6" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 231.7;Corticotrophs: 217.7;Gonadotrophs: 249.6;Lactotrophs: 288.4;Pituicytes/FSCs: 250.6;Somatotrophs: 316.3;Thyrotrophs: 234.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 10.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024771, HPA024779" Uncertain NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 34: Non-specific - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" "HPA024771: , HPA024779: " "unprognostic (1.02e-1)" "unprognostic (1.54e-1)" "unprognostic (1.30e-2)" "unprognostic (5.12e-1)" "unprognostic (1.02e-2)" "unprognostic (2.88e-3)" "unprognostic (7.92e-2)" "unprognostic (1.70e-2)" "unprognostic (1.97e-3)" "unprognostic (1.40e-2)" "unprognostic (1.20e-1)" "unprognostic (2.94e-1)" "unprognostic (1.94e-1)" "unprognostic (3.07e-3)" "unprognostic (1.29e-3)" "unprognostic (6.65e-2)" "unprognostic (1.11e-2)" "unprognostic (1.70e-1)" "unprognostic (1.88e-1)" "unprognostic (4.34e-2)" MID1 "FXY, OS, RNF59, TRIM18" ENSG00000101871 "Midline 1" O15344 X 10445310-10833654 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 1189.6;Endometrial luminal cells: 496.8;Retinal horizontal cells: 671.1;Urothelial cells: 599.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Breast myoepithelial cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002878, HPA003715" Approved Uncertain "Golgi apparatus,Centriolar satellite,Cytosol" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 15: Non-specific - Transcription" "Cluster 72: Neuronal - Signal transduction" "Cluster 51: Secretory epithelial cells - Mixed function" 62 "Centriolar satellite" "Golgi apparatus, Cytosol" "HPA002878: , HPA003715: " "unprognostic (1.51e-1)" "unprognostic (1.79e-1)" "unprognostic (6.04e-2)" "unprognostic (2.11e-1)" "unprognostic (1.63e-2)" "unprognostic (1.08e-1)" "unprognostic (2.23e-1)" "unprognostic (4.07e-2)" "unprognostic (1.60e-1)" "unprognostic (2.96e-2)" "validated prognostic favorable (1.73e-5)" "validated prognostic favorable (6.22e-4)" "unprognostic (2.04e-2)" "potential prognostic unfavorable (1.63e-4)" "unprognostic (2.53e-3)" "unprognostic (3.04e-2)" "unprognostic (1.83e-1)" "unprognostic (4.10e-1)" "unprognostic (2.64e-2)" "unprognostic (7.54e-2)" "unprognostic (1.50e-2)" "unprognostic (4.35e-1)" "unprognostic (3.98e-2)" "unprognostic (3.27e-1)" "unprognostic (6.71e-2)" "unprognostic (5.68e-2)" "unprognostic (9.45e-2)" "unprognostic (1.89e-1)" "unprognostic (2.21e-1)" "potential prognostic unfavorable (2.59e-4)" "unprognostic (1.87e-1)" MID1IP1 "FLJ10386, G12-like, MIG12, STRAIT11499, THRSPL" ENSG00000165175 "MID1 interacting protein 1" Q9NPA3 X 38801440-38806537 "Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 154.5;skeletal muscle: 140.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 308.6;Neutrophils: 201.2" "Cell type enhanced" "Detected in all" "oligodendrocyte: 65.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 15.7" "Lineage enriched" "Detected in many" 8 "granulocytes: 15.7" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Skin - Macrophages, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038816 Uncertain NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 12 "HPA038816: " "unprognostic (7.98e-2)" "unprognostic (4.98e-2)" "unprognostic (1.87e-1)" "unprognostic (2.81e-1)" "unprognostic (3.93e-1)" "unprognostic (3.22e-3)" "unprognostic (1.61e-1)" "unprognostic (6.87e-2)" "unprognostic (5.82e-2)" "unprognostic (8.60e-2)" "unprognostic (1.20e-3)" "unprognostic (7.85e-3)" "unprognostic (1.79e-2)" "potential prognostic unfavorable (7.22e-5)" "unprognostic (1.15e-2)" "unprognostic (1.11e-1)" "unprognostic (2.82e-1)" "unprognostic (1.79e-1)" "unprognostic (1.37e-1)" "unprognostic (1.11e-1)" "unprognostic (1.28e-2)" "unprognostic (3.01e-1)" "unprognostic (7.20e-3)" "potential prognostic unfavorable (2.49e-4)" "unprognostic (2.01e-2)" "unprognostic (2.88e-1)" "unprognostic (2.74e-1)" "unprognostic (1.12e-1)" "unprognostic (1.93e-1)" "unprognostic (1.64e-2)" "unprognostic (1.69e-2)" MID2 "FXY2, MRX101, RNF60, TRIM1" ENSG00000080561 "Midline 2" Q9UJV3 X 107825755-107931637 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 63.6;Lymphatic endothelial cells: 67.5;Prostatic glandular cells: 74.3;Urothelial cells: 108.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Lineage enriched" "Detected in single" 6 "T-cells: 1.6" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 36: Non-specific - mRNA processing" "Cluster 69: Urothelial cells - Basic cellular functions" 23 "unprognostic (3.88e-2)" "unprognostic (6.01e-2)" "unprognostic (1.86e-1)" "unprognostic (1.22e-2)" "unprognostic (5.07e-3)" "unprognostic (1.52e-2)" "unprognostic (2.80e-1)" "unprognostic (2.35e-2)" "unprognostic (6.81e-2)" "unprognostic (3.79e-2)" "validated prognostic favorable (3.85e-10)" "validated prognostic favorable (4.44e-4)" "unprognostic (9.19e-2)" "unprognostic (2.77e-1)" "unprognostic (1.53e-2)" "unprognostic (1.31e-1)" "unprognostic (1.91e-3)" "unprognostic (3.97e-2)" "unprognostic (2.04e-1)" "unprognostic (7.44e-2)" "unprognostic (2.67e-2)" "unprognostic (1.45e-1)" "unprognostic (1.69e-2)" "unprognostic (3.37e-1)" "unprognostic (5.62e-2)" "unprognostic (2.94e-1)" "unprognostic (9.47e-3)" "unprognostic (1.06e-3)" "unprognostic (1.26e-1)" "unprognostic (3.10e-1)" "unprognostic (8.65e-2)" MIDEAS "C14orf117, C14orf43, ELMSAN1, LSR68" ENSG00000156030 "Mitotic deacetylase associated SANT domain protein" Q6PJG2 14 73715122-73790285 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 252.1;Epicardial cells: 582.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003111 Approved Enhanced Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 55: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 26 Nucleoplasm "HPA003111: " "unprognostic (7.64e-3)" "unprognostic (9.44e-2)" "unprognostic (1.05e-1)" "unprognostic (2.07e-1)" "unprognostic (1.31e-1)" "unprognostic (2.09e-1)" "unprognostic (3.30e-1)" "unprognostic (3.07e-2)" "unprognostic (1.75e-1)" "potential prognostic favorable (2.61e-6)" "unprognostic (8.83e-3)" "unprognostic (2.10e-2)" "unprognostic (1.57e-1)" "unprognostic (3.11e-1)" "unprognostic (4.73e-2)" "unprognostic (3.48e-2)" "unprognostic (2.65e-1)" "unprognostic (1.65e-3)" "unprognostic (3.91e-2)" "unprognostic (3.30e-2)" "unprognostic (3.07e-2)" "unprognostic (1.74e-1)" "unprognostic (3.55e-2)" "unprognostic (1.86e-2)" "unprognostic (1.26e-1)" "unprognostic (3.77e-1)" "unprognostic (3.76e-1)" "unprognostic (1.56e-2)" "unprognostic (2.40e-1)" MIDN Stx ENSG00000167470 Midnolin Q504T8 19 1248553-1259143 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 772.5;Neutrophils: 749.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 11.7" "Lineage enriched" "Detected in many" 9 "granulocytes: 11.7" "Low cancer specificity" "Detected in all" "Colon - Neutrophils, Liver - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042018, HPA049432" Uncertain Approved Nucleoplasm Yes No "Cluster 35: Neutrophils - Protein binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 20: Non-specific - Transcription regulation" 27 Nucleoplasm "HPA042018: , HPA049432: " "unprognostic (3.48e-2)" "unprognostic (2.19e-1)" "unprognostic (2.88e-1)" "unprognostic (2.51e-3)" "unprognostic (3.56e-2)" "unprognostic (3.02e-1)" "unprognostic (2.45e-1)" "unprognostic (2.21e-1)" "unprognostic (1.61e-1)" "unprognostic (1.31e-1)" "unprognostic (8.54e-3)" "unprognostic (2.70e-2)" "unprognostic (3.87e-2)" "potential prognostic unfavorable (8.43e-4)" "unprognostic (1.36e-1)" "unprognostic (2.99e-2)" "unprognostic (2.93e-2)" "unprognostic (6.33e-3)" "unprognostic (1.01e-1)" "unprognostic (1.75e-1)" "unprognostic (3.93e-1)" "unprognostic (3.79e-1)" "unprognostic (2.52e-2)" "unprognostic (3.53e-2)" "unprognostic (1.29e-1)" "unprognostic (1.81e-1)" "unprognostic (2.02e-1)" "unprognostic (2.60e-1)" "unprognostic (3.26e-1)" "unprognostic (1.50e-1)" "unprognostic (2.70e-2)" MIEF1 "FLJ20232, L0R8F8, MiD51, SMCR7L" ENSG00000100335 "Mitochondrial elongation factor 1" Q9NQG6 22 39499432-39518132 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Early spermatids: 303.0;Late spermatids: 624.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061059 Uncertain "Intermediate filaments,Mitochondria" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 76: Non-specific - Metabolism" "Cluster 45: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 26 "Intermediate filaments, Mitochondria" "HPA061059: " "unprognostic (2.32e-1)" "unprognostic (4.28e-2)" "unprognostic (2.57e-1)" "unprognostic (9.12e-2)" "unprognostic (1.17e-1)" "unprognostic (5.04e-2)" "unprognostic (2.91e-1)" "unprognostic (9.03e-2)" "unprognostic (6.81e-3)" "potential prognostic favorable (1.61e-5)" "unprognostic (9.86e-3)" "unprognostic (5.95e-2)" "unprognostic (1.37e-3)" "potential prognostic unfavorable (3.10e-4)" "unprognostic (1.17e-2)" "unprognostic (7.70e-2)" "unprognostic (2.85e-2)" "unprognostic (2.65e-1)" "unprognostic (1.25e-1)" "unprognostic (2.50e-1)" "unprognostic (1.13e-1)" "unprognostic (1.36e-1)" "potential prognostic favorable (1.15e-4)" "unprognostic (3.11e-1)" "unprognostic (1.73e-1)" "unprognostic (7.23e-2)" "unprognostic (1.50e-1)" "unprognostic (1.34e-2)" "unprognostic (1.91e-1)" MIEF2 "MGC23130, MiD49, SMCR7" ENSG00000177427 "Mitochondrial elongation factor 2" Q96C03 17 18260597-18266552 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 10.6;Astrocytes: 5.4;Bergmann glia: 3.7;Brain excitatory neurons: 6.2;Brain inhibitory neurons: 6.3;Choroid plexus epithelial cells: 4.9;Distal convoluted tubule cells: 6.8;Ependymal cells: 6.6;Loop of henle epithelial cells: 7.6;Oligodendrocyte progenitor cells: 4.1;Oligodendrocytes: 4.2;Other brain neurons: 8.6;Papillary tip epithelial cells: 4.0;Proximal tubule cells: 4.9;Renal collecting duct intercalated cells: 6.5;Renal collecting duct principal cells: 7.1;Renal connecting tubule cells: 7.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Minor Salivary Gland - Minor salivary glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042334 Uncertain NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 42: Non-specific - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" 6 "HPA042334: " "unprognostic (7.58e-3)" "unprognostic (9.85e-2)" "unprognostic (3.10e-2)" "unprognostic (2.80e-1)" "unprognostic (3.04e-2)" "unprognostic (1.39e-3)" "unprognostic (4.31e-2)" "unprognostic (3.37e-2)" "unprognostic (3.57e-1)" "potential prognostic favorable (3.55e-7)" "unprognostic (1.64e-2)" "potential prognostic favorable (6.55e-5)" "unprognostic (2.46e-2)" "unprognostic (1.84e-2)" "unprognostic (2.57e-2)" "unprognostic (3.92e-2)" "unprognostic (5.43e-1)" "unprognostic (6.81e-2)" "unprognostic (7.69e-2)" "unprognostic (2.00e-2)" "unprognostic (3.31e-2)" "unprognostic (1.12e-1)" "unprognostic (4.44e-3)" "unprognostic (1.00e-1)" "unprognostic (2.85e-1)" "unprognostic (8.71e-2)" "unprognostic (1.26e-1)" "unprognostic (4.34e-2)" "unprognostic (1.90e-1)" MIEN1 "C17orf37, C35, MGC14832, ORB3, Rdx12, XTP4" ENSG00000141741 "Migration and invasion enhancer 1" Q9BRT3 17 39728496-39730532 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 443.5;Esophageal suprabasal cells: 269.6;Gastric progenitor cells: 464.0;Late primary spermatocytes: 271.9;Syncytiotrophoblasts: 341.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "breast cancer: 293.7" "Breast - Breast glandular cells, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056650, HPA061344" Approved Supported "Plasma membrane,Cytosol" NA NA 65000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 11 "Plasma membrane, Cytosol" "HPA056650: , HPA061344: " "unprognostic (1.02e-1)" "unprognostic (3.01e-1)" "unprognostic (4.12e-2)" "unprognostic (3.98e-1)" "unprognostic (4.10e-2)" "unprognostic (2.71e-2)" "unprognostic (1.08e-1)" "unprognostic (3.25e-2)" "unprognostic (6.63e-2)" "unprognostic (5.09e-2)" "unprognostic (1.82e-2)" "unprognostic (9.45e-2)" "unprognostic (6.43e-2)" "unprognostic (3.90e-1)" "unprognostic (1.63e-1)" "unprognostic (1.21e-1)" "unprognostic (2.52e-1)" "unprognostic (6.29e-2)" "unprognostic (3.41e-1)" "unprognostic (1.58e-1)" "unprognostic (3.19e-1)" "unprognostic (1.27e-1)" "unprognostic (3.66e-1)" "unprognostic (8.54e-2)" "unprognostic (6.39e-2)" "unprognostic (3.19e-2)" "unprognostic (4.20e-2)" "unprognostic (3.85e-3)" "unprognostic (1.19e-1)" MIER1 "hMI-ER1, KIAA1610, MI-ER1" ENSG00000198160 "MIER1 transcriptional regulator" Q8N108 1 66924895-66988619 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 92.4" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 673.1;Neutrophils: 611.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019589, HPA050306" Enhanced Enhanced Nucleoplasm "Intracellular and membrane" Transcription NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 12 Nucleoplasm "HPA019589: , HPA050306: " "potential prognostic favorable (7.51e-4)" "unprognostic (4.31e-2)" "unprognostic (9.36e-3)" "unprognostic (1.92e-2)" "unprognostic (9.63e-3)" "unprognostic (4.61e-1)" "unprognostic (4.91e-3)" "unprognostic (8.82e-2)" "unprognostic (3.13e-2)" "unprognostic (1.29e-2)" "potential prognostic favorable (6.50e-6)" "unprognostic (1.65e-2)" "unprognostic (2.07e-1)" "unprognostic (3.74e-3)" "unprognostic (1.18e-1)" "unprognostic (2.32e-1)" "unprognostic (8.56e-2)" "unprognostic (8.05e-2)" "unprognostic (4.67e-2)" "unprognostic (1.09e-1)" "unprognostic (5.41e-3)" "potential prognostic unfavorable (4.92e-4)" "unprognostic (2.23e-1)" "unprognostic (1.04e-1)" "unprognostic (1.61e-2)" "unprognostic (1.33e-1)" "unprognostic (1.70e-1)" "unprognostic (2.77e-2)" "unprognostic (1.74e-1)" "unprognostic (1.92e-2)" "unprognostic (2.83e-1)" MIER2 KIAA1193 ENSG00000105556 "MIER family member 2" Q8N344 19 305573-344815 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cell type enhanced" "Detected in all" "endothelial cell: 57.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041439, HPA066153" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 13 "Nucleoplasm, Cytosol" "HPA041439: , HPA066153: " "unprognostic (7.53e-2)" "unprognostic (4.05e-1)" "unprognostic (9.62e-2)" "unprognostic (1.14e-1)" "unprognostic (9.16e-3)" "unprognostic (3.27e-3)" "unprognostic (2.70e-1)" "unprognostic (2.14e-1)" "unprognostic (2.24e-1)" "unprognostic (4.34e-2)" "unprognostic (7.52e-2)" "unprognostic (8.03e-3)" "unprognostic (9.69e-2)" "unprognostic (5.68e-3)" "unprognostic (2.67e-1)" "unprognostic (1.14e-1)" "unprognostic (4.69e-2)" "unprognostic (5.29e-2)" "unprognostic (8.36e-2)" "unprognostic (1.71e-1)" "unprognostic (1.76e-1)" "unprognostic (4.78e-3)" "unprognostic (4.84e-3)" "unprognostic (9.08e-2)" "unprognostic (3.42e-2)" "unprognostic (1.20e-2)" "unprognostic (2.31e-1)" "unprognostic (1.57e-1)" "unprognostic (7.16e-2)" "unprognostic (7.30e-2)" "unprognostic (4.84e-2)" MIER3 "DKFZp686L09111, DKFZp781I1119, FLJ35954" ENSG00000155545 "MIER family member 3" Q7Z3K6 5 56919602-56971675 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 105.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058349, HPA065946" Uncertain Enhanced Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 77: Intestine - Digestion" "Cluster 25: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 7 Nucleoplasm "HPA058349: , HPA065946: " "unprognostic (9.49e-2)" "unprognostic (1.68e-1)" "unprognostic (1.74e-1)" "unprognostic (2.23e-2)" "unprognostic (6.99e-2)" "unprognostic (1.88e-2)" "unprognostic (2.12e-1)" "unprognostic (5.33e-1)" "unprognostic (1.43e-1)" "unprognostic (4.47e-3)" "potential prognostic favorable (6.05e-4)" "unprognostic (2.18e-3)" "unprognostic (2.80e-1)" "unprognostic (8.51e-3)" "unprognostic (2.38e-1)" "unprognostic (8.56e-2)" "unprognostic (4.00e-2)" "unprognostic (1.72e-1)" "unprognostic (1.27e-1)" "unprognostic (2.26e-1)" "unprognostic (1.14e-1)" "unprognostic (3.93e-2)" "unprognostic (8.85e-3)" "unprognostic (4.39e-2)" "unprognostic (5.20e-2)" "unprognostic (9.81e-2)" "unprognostic (7.24e-3)" "unprognostic (4.22e-1)" "unprognostic (1.72e-1)" "unprognostic (1.30e-2)" "unprognostic (1.92e-1)" MIF "GIF, GLIF" ENSG00000240972 "Macrophage migration inhibitory factor" P14174 22 23894383-23895227 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Cytokine, Isomerase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 786.6;Esophageal apical cells: 652.6;Extravillous trophoblasts: 637.0;Gastric chief cells: 823.4;Parietal cells: 887.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003868, CAB005284" Approved Enhanced Nucleoplasm,Cytosol "Secreted to blood" Cytokine No No 13800000 2500000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 97: Non-specific - Cellular respiration" 112 Cytosol Nucleoplasm "CAB005284: , HPA003868: " "unprognostic (1.70e-2)" "unprognostic (1.62e-1)" "unprognostic (2.78e-1)" "unprognostic (5.73e-3)" "unprognostic (7.28e-2)" "unprognostic (2.11e-1)" "unprognostic (2.92e-1)" "unprognostic (1.31e-1)" "potential prognostic unfavorable (7.58e-4)" "unprognostic (2.54e-2)" "unprognostic (5.68e-2)" "unprognostic (1.03e-1)" "unprognostic (1.39e-1)" "unprognostic (9.21e-3)" "potential prognostic unfavorable (5.90e-5)" "validated prognostic unfavorable (8.93e-5)" "validated prognostic unfavorable (6.75e-4)" "unprognostic (2.84e-2)" "unprognostic (2.93e-1)" "unprognostic (1.33e-1)" "unprognostic (2.78e-2)" "unprognostic (1.43e-1)" "unprognostic (2.62e-2)" "unprognostic (7.36e-2)" "unprognostic (8.19e-2)" "unprognostic (2.40e-1)" "unprognostic (1.78e-2)" "unprognostic (1.87e-1)" "unprognostic (1.41e-1)" "unprognostic (4.15e-2)" "unprognostic (8.42e-2)" MIF4GD "AD023, MGC45027, MIFD, SLIP1" ENSG00000125457 "MIF4G domain containing" A9UHW6 17 75266228-75271231 "Predicted intracellular proteins" "Translation regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 82.8;Esophageal suprabasal cells: 71.8;Megakaryocytes: 136.0;pDCs: 90.9;Platelets: 129.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051222 Approved Supported "Nucleoli,Golgi apparatus,Cytosol" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 22 Nucleoli "Golgi apparatus, Cytosol" "HPA051222: " "unprognostic (9.17e-2)" "unprognostic (1.40e-1)" "unprognostic (1.57e-2)" "unprognostic (2.10e-1)" "unprognostic (1.01e-1)" "unprognostic (3.37e-2)" "unprognostic (1.59e-1)" "unprognostic (8.51e-2)" "unprognostic (2.43e-1)" "unprognostic (2.41e-1)" "unprognostic (5.50e-3)" "unprognostic (1.58e-1)" "unprognostic (6.20e-2)" "unprognostic (2.48e-2)" "unprognostic (8.10e-3)" "unprognostic (1.17e-1)" "unprognostic (6.49e-2)" "unprognostic (4.36e-2)" "unprognostic (1.36e-2)" "unprognostic (2.64e-2)" "unprognostic (2.18e-1)" "unprognostic (1.69e-3)" "unprognostic (3.15e-2)" "unprognostic (1.08e-1)" "unprognostic (1.99e-1)" "unprognostic (2.14e-1)" "unprognostic (8.88e-2)" "unprognostic (7.88e-2)" "unprognostic (1.12e-1)" "unprognostic (1.19e-1)" "unprognostic (5.11e-3)" MIGA1 "FAM73A, FLJ35093" ENSG00000180488 "Mitoguardin 1" Q8NAN2 1 77779624-77879540 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017589 Approved Supported Mitochondria NA NA "Cluster 24: Non-specific - Transcription" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 7: Non-specific - Transcription" 3 Mitochondria "HPA017589: " "unprognostic (3.52e-1)" "unprognostic (1.89e-1)" "unprognostic (4.73e-3)" "unprognostic (1.73e-2)" "unprognostic (1.32e-1)" "unprognostic (1.66e-1)" "unprognostic (1.68e-1)" "unprognostic (6.02e-2)" "unprognostic (7.54e-2)" "validated prognostic favorable (1.76e-7)" "validated prognostic favorable (9.36e-6)" "unprognostic (2.41e-1)" "unprognostic (1.74e-2)" "unprognostic (3.31e-2)" "unprognostic (1.16e-1)" "unprognostic (2.78e-1)" "unprognostic (1.67e-1)" "unprognostic (2.61e-2)" "potential prognostic unfavorable (6.27e-5)" "unprognostic (2.01e-1)" "unprognostic (1.78e-2)" "unprognostic (1.55e-1)" "unprognostic (3.50e-2)" "unprognostic (1.05e-1)" "unprognostic (1.76e-1)" "unprognostic (1.83e-1)" "unprognostic (1.47e-1)" "unprognostic (1.27e-2)" "unprognostic (9.38e-2)" MIGA2 "C9orf54, FAM73B, FLJ00199, FLJ14596" ENSG00000148343 "Mitoguardin 2" Q7L4E1 9 129036621-129072082 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Platelets: 125.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041363 Approved Approved "Cell Junctions,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 45: Non-specific - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 47: Platelets - Hemostasis" 9 Cytosol "Cell Junctions" "HPA041363: " "unprognostic (5.76e-3)" "unprognostic (2.52e-1)" "unprognostic (4.00e-2)" "unprognostic (2.95e-1)" "unprognostic (6.57e-2)" "unprognostic (1.27e-1)" "potential prognostic favorable (1.31e-4)" "unprognostic (1.50e-1)" "unprognostic (3.52e-1)" "potential prognostic favorable (9.30e-6)" "unprognostic (4.06e-3)" "unprognostic (5.45e-3)" "unprognostic (4.59e-2)" "unprognostic (2.99e-2)" "unprognostic (4.22e-1)" "unprognostic (3.71e-2)" "unprognostic (2.60e-2)" "unprognostic (1.11e-2)" "unprognostic (5.66e-2)" "unprognostic (1.22e-3)" "unprognostic (2.10e-1)" "unprognostic (1.03e-1)" "unprognostic (2.17e-1)" "unprognostic (2.62e-1)" "unprognostic (7.90e-2)" "unprognostic (6.34e-3)" "unprognostic (9.77e-2)" "unprognostic (1.74e-1)" "unprognostic (2.91e-2)" MIIP "FLJ12438, IIp45" ENSG00000116691 "Migration and invasion inhibitory protein" Q5JXC2 1 12019466-12032045 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 201.0;Extravillous trophoblasts: 139.0;Late spermatids: 70.8;Mast cells: 69.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044948 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 24: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 4: Breast lactating luminal cells - Lactation" 38 Nucleoplasm Cytosol "HPA044948: " "unprognostic (7.16e-2)" "unprognostic (2.43e-2)" "unprognostic (4.71e-1)" "unprognostic (2.67e-1)" "unprognostic (1.46e-1)" "unprognostic (1.05e-2)" "unprognostic (1.23e-1)" "potential prognostic favorable (8.99e-4)" "unprognostic (1.63e-1)" "unprognostic (1.26e-1)" "potential prognostic unfavorable (1.68e-5)" "unprognostic (3.75e-2)" "unprognostic (4.93e-2)" "validated prognostic unfavorable (4.46e-4)" "validated prognostic unfavorable (7.34e-4)" "unprognostic (1.34e-2)" "unprognostic (1.41e-1)" "unprognostic (1.71e-1)" "unprognostic (2.42e-1)" "unprognostic (6.95e-2)" "unprognostic (8.80e-2)" "unprognostic (1.39e-2)" "unprognostic (2.66e-1)" "unprognostic (3.10e-1)" "unprognostic (1.32e-1)" "unprognostic (2.07e-3)" "unprognostic (6.26e-2)" "unprognostic (1.12e-1)" "unprognostic (1.87e-1)" "unprognostic (9.32e-2)" "unprognostic (3.04e-2)" MILR1 "Allergin-1, C17orf60, MCA-32" ENSG00000271605 "Mast cell immunoglobulin like receptor 1" Q7Z6M3 17 64449037-64468643 "Essential proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 23.9" "Cell type enhanced" "Detected in many" "cDC: 30.7;Epicardial cells: 102.3;Hofbauer cells: 144.8;Kupffer cells: 42.0;Macrophages: 36.4;Microglia: 77.4;monocytes: 34.1;Neutrophils: 34.0;pDCs: 50.7;Tuft cells: 34.6" "Cell type enriched" "Detected in some" 24 "central nervous system macrophage: 96.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 83.1" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Bile duct cancer: 35.9" "Low region specificity" "Detected in all" HPA014347 Enhanced NA NA 99000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 6: Leukemia - Signal transduction" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 43 "HPA014347: " "unprognostic (1.40e-2)" "unprognostic (1.96e-1)" "unprognostic (2.01e-2)" "unprognostic (3.53e-3)" "unprognostic (2.19e-1)" "unprognostic (1.46e-1)" "unprognostic (1.02e-1)" "unprognostic (5.25e-3)" "potential prognostic unfavorable (5.97e-4)" "potential prognostic unfavorable (2.39e-4)" "unprognostic (1.14e-2)" "unprognostic (1.22e-1)" "unprognostic (5.11e-3)" "unprognostic (1.27e-1)" "unprognostic (1.34e-2)" "unprognostic (8.18e-2)" "unprognostic (2.55e-2)" "unprognostic (1.01e-3)" "unprognostic (7.41e-3)" "unprognostic (1.31e-1)" "unprognostic (1.82e-1)" "unprognostic (1.92e-2)" "unprognostic (1.70e-1)" "unprognostic (5.71e-3)" "unprognostic (1.88e-2)" "unprognostic (1.25e-1)" "unprognostic (6.21e-2)" MINAR1 "KIAA1024, UBTOR" ENSG00000169330 "Membrane integral NOTCH2 associated receptor 1" Q9UPX6 15 79432336-79472304 "Predicted membrane proteins" Angiogenesis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 9.7;brain: 7.3;retina: 6.3" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 131.5;Brain excitatory neurons: 15.5;Brain inhibitory neurons: 27.1;Müller glia: 64.3;Oligodendrocyte progenitor cells: 14.4;Other brain neurons: 14.1;Pancreatic duct cells: 19.7;Salivary acinar cells: 20.3;Thyrotrophs: 38.3" "Cell type enhanced" "Detected in many" "midbrain-derived inhibitory: 156.4" "Cancer enhanced" "Detected in single" "Skin Cutaneous Melanoma (TCGA): 2.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Thyrotropes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA011545 Uncertain Approved "Golgi apparatus" NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 18: Adrenal cortex cells - Steroidogensis" 5 "Golgi apparatus" "HPA011545: " "unprognostic (1.36e-2)" "unprognostic (1.52e-1)" "unprognostic (1.74e-1)" MINAR2 KIAA1024L ENSG00000186367 "Membrane integral NOTCH2 associated receptor 2" P59773 5 129748094-129766732 "Predicted membrane proteins" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 71 "skeletal muscle: 33.0" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 2.2;Brain inhibitory neurons: 2.6;Cytotrophoblasts: 4.3;Decidual stromal cells: 1.7;Endometrial stromal cells: 3.6;Foveolar cells: 1.2;Other brain neurons: 1.9;Podocytes: 14.7" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in single" "Uterine Corpus Endometrial Carcinoma (TCGA): 1.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" HPA013760 Uncertain NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 34: Non-specific - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 57: Podocytes - Glomerular filtration" "HPA013760: " "unprognostic (3.57e-1)" MINDY1 "FAM63A, FLJ11280, MINDY-1" ENSG00000143409 "MINDY lysine 48 deubiquitinase 1" Q8N5J2 1 150996549-151008376 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 150.4;Neutrophils: 91.6;Platelets: 476.3" "Cell type enhanced" "Detected in many" "endothelial cell: 35.0;oligodendrocyte: 28.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "basophil: 99.8;eosinophil: 56.7;neutrophil: 93.9" "Lineage enriched" "Detected in all" 8 "granulocytes: 99.8" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028358, HPA061086" Supported Nucleoplasm NA NA 55000 "Cluster 21: Neutrophils - Unknown function" "Cluster 82: Salivary gland - Secretion" "Cluster 6: Non-specific - Immune response" "Cluster 7: Liver cancer - Metabolism" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 2 Nucleoplasm "HPA028358: , HPA061086: " "unprognostic (3.65e-3)" "unprognostic (2.67e-1)" "unprognostic (3.51e-2)" "unprognostic (7.52e-2)" "unprognostic (1.44e-1)" "unprognostic (9.13e-2)" "unprognostic (4.63e-2)" "unprognostic (3.20e-2)" "unprognostic (7.81e-2)" "validated prognostic favorable (7.56e-8)" "validated prognostic favorable (4.97e-8)" "unprognostic (4.82e-2)" "unprognostic (3.55e-2)" "unprognostic (2.36e-1)" "unprognostic (2.08e-1)" "unprognostic (1.98e-3)" "unprognostic (3.41e-2)" "unprognostic (6.67e-2)" "unprognostic (2.13e-1)" "unprognostic (4.58e-2)" "unprognostic (1.22e-1)" "unprognostic (2.01e-1)" "unprognostic (1.37e-2)" "unprognostic (1.09e-1)" "unprognostic (5.75e-2)" "unprognostic (7.11e-2)" "unprognostic (4.66e-2)" "unprognostic (2.36e-2)" "unprognostic (1.06e-1)" MINDY2 "FAM63B, KIAA1164" ENSG00000128923 "MINDY lysine 48 deubiquitinase 2" Q8NBR6 15 58771192-58861900 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051103, HPA063669" Approved Enhanced Nucleoplasm No No "Cluster 20: Non-specific - DNA binding" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 25: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 62: Smooth muscle cells - Muscle contraction" 1 Nucleoplasm "HPA051103: , HPA063669: " "potential prognostic favorable (1.95e-4)" "unprognostic (7.09e-2)" "unprognostic (1.17e-3)" "unprognostic (7.49e-2)" "unprognostic (9.34e-2)" "unprognostic (9.35e-2)" "unprognostic (1.46e-2)" "unprognostic (2.04e-1)" "unprognostic (4.01e-2)" "potential prognostic favorable (3.22e-6)" "unprognostic (2.09e-3)" "unprognostic (1.39e-1)" "unprognostic (3.96e-2)" "unprognostic (3.58e-2)" "unprognostic (5.49e-2)" "unprognostic (2.18e-1)" "unprognostic (1.80e-1)" "unprognostic (3.57e-2)" "unprognostic (3.01e-2)" "unprognostic (6.28e-3)" "unprognostic (1.37e-2)" "unprognostic (1.16e-1)" "unprognostic (8.30e-2)" "unprognostic (2.75e-1)" "unprognostic (5.28e-2)" "unprognostic (4.46e-1)" "unprognostic (3.13e-1)" "unprognostic (4.94e-2)" "unprognostic (1.48e-1)" MINDY3 "C10orf97, CARP, DERP5, FAM188A, FLJ13397, my042" ENSG00000148481 "MINDY lysine 48 deubiquitinase 3" Q9H8M7 10 15778170-15860507 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038400, HPA038406" Uncertain Supported "Nucleoplasm,Nuclear membrane,Microtubules,Primary cilium,Primary cilium tip,Cytosol" NA NA 11000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 55: Breast - Lactation" "Cluster 34: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 7: Non-specific - Transcription" 9 "Nucleoplasm, Nuclear membrane" "Microtubules, Primary cilium, Primary cilium tip, Cytosol" "HPA038400: , HPA038406: " "unprognostic (9.23e-2)" "unprognostic (8.05e-2)" "unprognostic (1.95e-1)" "unprognostic (1.57e-1)" "unprognostic (1.60e-2)" "unprognostic (2.54e-2)" "potential prognostic favorable (3.41e-5)" "unprognostic (1.80e-1)" "unprognostic (5.03e-2)" "potential prognostic favorable (1.20e-6)" "unprognostic (2.02e-2)" "unprognostic (2.18e-1)" "unprognostic (8.43e-2)" "unprognostic (2.02e-1)" "unprognostic (8.79e-2)" "unprognostic (5.46e-2)" "unprognostic (3.17e-1)" "unprognostic (8.01e-2)" "unprognostic (1.41e-3)" "unprognostic (7.29e-3)" "unprognostic (3.02e-2)" "unprognostic (1.08e-1)" "unprognostic (2.30e-2)" "unprognostic (4.89e-2)" "unprognostic (3.32e-1)" "unprognostic (1.58e-1)" "unprognostic (2.95e-1)" "unprognostic (3.43e-1)" "unprognostic (2.11e-2)" MINDY4 "C7orf67, FAM188B, FLJ22374" ENSG00000106125 "MINDY lysine 48 deubiquitinase 4" Q4G0A6 7 30771417-30892387 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 4.0;Choroid plexus epithelial cells: 3.8;Endometrial ciliated cells: 7.8;Ependymal cells: 18.6;Fallopian tube ciliated cells: 6.4;Gonadotrophs: 6.8;Mesothelial cells: 4.5;Thyrotrophs: 4.2" "Cell type enhanced" "Detected in many" "ependymal cell: 21.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Prostate - Smooth muscle cells, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019475, HPA030129, HPA030130" Approved Supported Vesicles,Cytosol NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 67: Non-specific - Unknown function" "Cluster 34: Ciliated cells - Cilia assembly & function" 2 "Vesicles, Cytosol" "HPA019475: , HPA030129: , HPA030130: " "unprognostic (4.10e-2)" "unprognostic (2.88e-1)" "unprognostic (3.86e-1)" "unprognostic (1.50e-1)" "unprognostic (6.30e-2)" "unprognostic (2.43e-1)" "unprognostic (5.92e-2)" "unprognostic (1.76e-1)" "unprognostic (3.23e-1)" "validated prognostic favorable (5.63e-7)" "validated prognostic favorable (3.69e-6)" "unprognostic (1.86e-1)" "unprognostic (1.19e-2)" "unprognostic (2.06e-2)" "unprognostic (1.74e-1)" "unprognostic (1.25e-1)" "unprognostic (1.39e-1)" "unprognostic (2.72e-1)" "unprognostic (7.63e-2)" "unprognostic (3.10e-1)" "unprognostic (7.20e-2)" "unprognostic (2.91e-2)" "unprognostic (5.71e-2)" "unprognostic (5.13e-3)" "unprognostic (9.99e-3)" "unprognostic (2.92e-1)" "unprognostic (6.64e-2)" "unprognostic (1.08e-3)" "unprognostic (2.62e-1)" MINDY4B "C3orf76, FAM188B2" ENSG00000214237 "MINDY family member 4B" A8MYZ0 3 150870376-150905439 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 4 "brain: 3.6" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 1.2;Epicardial cells: 6.8;Foveolar cells: 1.6;Leydig cells: 1.6;Mucous neck cells: 2.0;Neutrophils: 3.8;Peritubular myoid cells: 2.6;Respiratory ionocytes: 2.5;Retinal horizontal cells: 2.0;Thymic myoid cells: 1.4" "Cell type enriched" "Detected in single" 4 "medium spiny neuron: 2.5" "Not detected" "Not detected" "Region enriched" "Detected in single" 4 "basal ganglia: 3.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Spleen - Neutrophils_2" "Low region specificity" "Detected in many" "Not detected" "Not detected" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 24: Neutrophils - Innate immunity signal integration" MINK1 "B55, MAP4K6, MINK, YSK2, ZC3" ENSG00000141503 "Misshapen like kinase 1" Q8N4C8 17 4833340-4898061 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 233.9;Suprabasal keratinocytes: 188.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056296 Approved NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 2: Non-specific - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 85: Squamous epithelial cells - Keratinization" 42 "HPA056296: " "unprognostic (3.10e-1)" "unprognostic (6.99e-2)" "unprognostic (7.03e-2)" "unprognostic (7.08e-3)" "unprognostic (1.06e-1)" "unprognostic (1.25e-1)" "unprognostic (4.15e-1)" "unprognostic (3.06e-3)" "unprognostic (3.77e-3)" "unprognostic (1.33e-1)" "potential prognostic favorable (2.08e-5)" "unprognostic (1.25e-2)" "unprognostic (2.12e-2)" "unprognostic (6.16e-2)" "unprognostic (4.84e-2)" "unprognostic (1.84e-1)" "unprognostic (2.71e-1)" "unprognostic (1.45e-2)" "unprognostic (8.23e-2)" "unprognostic (3.60e-2)" "unprognostic (1.10e-1)" "unprognostic (3.87e-2)" "unprognostic (3.18e-3)" "unprognostic (2.00e-2)" "unprognostic (8.85e-2)" "unprognostic (9.70e-2)" "unprognostic (4.66e-2)" "unprognostic (5.23e-2)" "unprognostic (1.28e-1)" "unprognostic (5.86e-2)" "unprognostic (1.67e-1)" MINPP1 MIPP ENSG00000107789 "Multiple inositol-polyphosphate phosphatase 1" Q9UNW1 10 87504875-87553461 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 225.0;Megakaryocyte progenitors: 79.5;Megakaryocyte-Erythroid progenitors: 121.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026859 Approved "Secreted to blood" Enzyme NA NA 130000000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 76: Non-specific - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 6 "HPA026859: " "unprognostic (1.00e-1)" "unprognostic (8.04e-3)" "unprognostic (1.62e-2)" "unprognostic (3.48e-3)" "unprognostic (2.72e-1)" "unprognostic (2.81e-2)" "unprognostic (2.09e-1)" "unprognostic (6.56e-3)" "unprognostic (1.83e-2)" "unprognostic (7.22e-2)" "potential prognostic favorable (7.17e-5)" "unprognostic (2.24e-1)" "potential prognostic unfavorable (1.04e-4)" "unprognostic (7.14e-2)" "unprognostic (3.32e-1)" "unprognostic (9.63e-3)" "unprognostic (1.01e-1)" "unprognostic (2.00e-1)" "unprognostic (8.79e-2)" "unprognostic (1.09e-2)" "unprognostic (1.45e-1)" "unprognostic (8.07e-2)" "unprognostic (6.34e-3)" "unprognostic (2.07e-3)" "unprognostic (1.39e-2)" "unprognostic (1.14e-1)" "unprognostic (2.76e-1)" "unprognostic (5.81e-2)" "unprognostic (1.58e-1)" "unprognostic (1.87e-2)" "unprognostic (2.71e-2)" MIOS "FLJ20323, MIO, Sea4, Yulink" ENSG00000164654 "Meiosis regulator for oocyte development" Q9NXC5 7 7566875-7608932 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 81.5" "Cell type enhanced" "Detected in all" "Thymic myoid cells: 310.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Spleen - B-cells (Spleen), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042928, HPA052223" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 67: Non-specific - Unknown function" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 29 Nucleoplasm Cytosol "HPA042928: , HPA052223: " "unprognostic (1.06e-1)" "potential prognostic unfavorable (5.59e-4)" "unprognostic (2.97e-1)" "unprognostic (5.94e-3)" "unprognostic (2.99e-1)" "unprognostic (1.15e-1)" "unprognostic (1.40e-1)" "unprognostic (6.48e-2)" "unprognostic (1.43e-1)" "unprognostic (3.21e-1)" "potential prognostic favorable (3.65e-9)" "unprognostic (6.89e-2)" "unprognostic (2.54e-1)" "unprognostic (3.05e-3)" "unprognostic (9.84e-3)" "unprognostic (2.11e-1)" "unprognostic (4.35e-3)" "unprognostic (1.62e-1)" "unprognostic (2.03e-1)" "unprognostic (6.78e-3)" "potential prognostic unfavorable (6.09e-5)" "unprognostic (6.74e-2)" "unprognostic (1.25e-1)" "unprognostic (7.33e-2)" "unprognostic (1.57e-3)" "unprognostic (4.36e-3)" "unprognostic (1.96e-1)" "unprognostic (2.75e-1)" "unprognostic (2.73e-1)" "unprognostic (1.57e-2)" "unprognostic (1.35e-1)" MIOX ALDRL6 ENSG00000100253 "Myo-inositol oxygenase" Q9UGB7 22 50486784-50490648 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 47 "kidney: 653.9" "Cell type enriched" "Detected in some" 14 "Proximal tubule cells: 498.0" "Not detected" "Not detected" "Group enriched" "Detected in many" 19 "Kidney Renal Clear Cell Carcinoma (TCGA): 111.2;Kidney Renal Papillary Cell Carcinoma (TCGA): 199.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney cancer: 5.5" "Kidney - Proximal tubular cells, Prostate - Prostate glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA039451, HPA039562" Enhanced NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 48: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 88: Proximal tubular cells - Transmembrane transport" 8 "HPA039451: , HPA039562: " "unprognostic (2.11e-1)" "unprognostic (8.07e-3)" "unprognostic (6.50e-3)" "unprognostic (4.75e-2)" "validated prognostic favorable (4.55e-8)" "validated prognostic favorable (6.98e-7)" "potential prognostic favorable (4.63e-5)" "unprognostic (5.19e-3)" "unprognostic (1.87e-1)" "unprognostic (1.36e-1)" "unprognostic (1.84e-2)" "unprognostic (9.46e-2)" "unprognostic (3.59e-3)" "unprognostic (3.87e-1)" "unprognostic (3.49e-3)" "unprognostic (3.65e-2)" MIP "AQP0, LIM1, MP26" ENSG00000135517 "Major intrinsic protein of lens fiber" P30301 12 56449502-56469166 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Sensory transduction, Transport, Vision" "Eye lens protein" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Cardiomyocytes: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA014940 Supported NA NA "Cluster 51: Myeloma - Immunoglobulins" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 36 "HPA014940: " MIPEP MIP ENSG00000027001 "Mitochondrial intermediate peptidase" Q99797 13 23730189-23889400 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 223.7;Ependymal cells: 317.0;Respiratory ciliated cells: 306.4" "Cell type enhanced" "Detected in all" "ependymal cell: 344.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030676, HPA031669, HPA031670" Approved Enhanced Mitochondria NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 29: Forebrain - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 34: Ciliated cells - Cilia assembly & function" 13 Mitochondria "HPA030676: , HPA031669: , HPA031670: " "unprognostic (1.82e-1)" "unprognostic (3.46e-2)" "unprognostic (2.89e-2)" "unprognostic (4.51e-2)" "unprognostic (1.47e-1)" "unprognostic (7.91e-2)" "unprognostic (1.25e-1)" "unprognostic (2.00e-2)" "unprognostic (4.35e-2)" "unprognostic (1.74e-1)" "potential prognostic favorable (2.64e-12)" "unprognostic (8.88e-2)" "potential prognostic favorable (4.54e-4)" "unprognostic (1.28e-1)" "unprognostic (1.42e-2)" "unprognostic (1.16e-1)" "unprognostic (1.80e-1)" "unprognostic (1.64e-1)" "unprognostic (6.46e-2)" "unprognostic (1.09e-1)" "unprognostic (1.57e-2)" "unprognostic (7.66e-2)" "unprognostic (1.07e-1)" "unprognostic (1.83e-1)" "unprognostic (3.35e-3)" "unprognostic (8.72e-3)" "unprognostic (3.14e-1)" "unprognostic (2.54e-2)" "unprognostic (2.71e-1)" "unprognostic (3.09e-1)" "unprognostic (1.69e-1)" MIPOL1 CCDC193 ENSG00000151338 "Mirror-image polydactyly 1" Q8TD10 14 37197894-37579125 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 6 "Prostatic glandular cells: 1813.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 1.5" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.5" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Spleen - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002893, HPA050179" Enhanced Supported Cytosol NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 61: Non-specific - Transcription" "Cluster 23: Choroid plexus - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 60 Cytosol "HPA002893: , HPA050179: " "unprognostic (2.40e-2)" "unprognostic (4.91e-2)" "unprognostic (2.84e-1)" "unprognostic (9.89e-2)" "unprognostic (2.55e-2)" "potential prognostic unfavorable (5.71e-4)" "potential prognostic favorable (1.36e-4)" "unprognostic (1.02e-1)" "unprognostic (3.08e-2)" "potential prognostic favorable (5.62e-4)" "unprognostic (1.07e-2)" "unprognostic (5.23e-2)" "validated prognostic unfavorable (6.01e-4)" "validated prognostic unfavorable (5.04e-4)" "unprognostic (6.97e-3)" "unprognostic (3.62e-3)" "unprognostic (2.22e-2)" "unprognostic (3.34e-1)" "unprognostic (1.60e-1)" "unprognostic (3.30e-1)" "unprognostic (1.54e-2)" "unprognostic (1.66e-2)" "unprognostic (6.90e-2)" "unprognostic (9.10e-2)" "unprognostic (4.47e-2)" "unprognostic (7.62e-3)" "unprognostic (2.77e-1)" "unprognostic (2.46e-2)" "unprognostic (1.79e-2)" "unprognostic (7.24e-2)" MIS12 "hMIS12, KNTC2AP, MGC2488, MTW1" ENSG00000167842 "MIS12 kinetochore complex component" Q9H081 17 5486285-5490814 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 119.6;Epididymal principal cells: 254.2;Late primary spermatocytes: 95.4;Late spermatids: 424.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044482 Approved NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 11: White matter - Signal transduction" "Cluster 42: Non-specific - Unknown function" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" 74 "HPA044482: " "unprognostic (1.06e-1)" "unprognostic (1.78e-2)" "unprognostic (2.45e-1)" "unprognostic (6.89e-2)" "unprognostic (2.99e-1)" "unprognostic (5.52e-2)" "unprognostic (5.03e-1)" "unprognostic (9.86e-2)" "unprognostic (3.21e-1)" "unprognostic (1.90e-3)" "unprognostic (3.13e-2)" "unprognostic (2.13e-1)" "unprognostic (1.04e-2)" "unprognostic (1.10e-1)" "unprognostic (9.23e-2)" "unprognostic (1.06e-1)" "unprognostic (2.18e-3)" "unprognostic (7.46e-2)" "unprognostic (1.01e-1)" "unprognostic (1.10e-1)" "unprognostic (2.16e-1)" "unprognostic (1.24e-3)" "unprognostic (1.82e-3)" "unprognostic (2.86e-2)" "unprognostic (1.12e-2)" "unprognostic (3.90e-2)" "unprognostic (4.38e-2)" "unprognostic (3.41e-1)" "unprognostic (3.96e-1)" "unprognostic (4.41e-3)" "unprognostic (3.44e-1)" MIS18A "B28, C21orf45, C21orf46, FASP1, hMis18alpha" ENSG00000159055 "MIS18 kinetochore protein A" Q9NYP9 21 32268228-32279049 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 97.2;Early primary spermatocytes: 120.7;Erythrocyte progenitors: 66.2;Extravillous trophoblasts: 61.1;Late primary spermatocytes: 69.7;Migrating cytotrophoblasts: 60.8;Oocytes: 101.3;Undifferentiated spermatogonia: 59.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA018286, HPA020585" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 34: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 27: Non-specific - Cell proliferation" 43 "Nucleoplasm, Cytosol" "HPA018286: , HPA020585: " "unprognostic (9.62e-2)" "unprognostic (2.79e-2)" "unprognostic (4.94e-2)" "unprognostic (1.31e-1)" "unprognostic (1.90e-1)" "unprognostic (1.47e-1)" "unprognostic (7.85e-2)" "unprognostic (4.19e-2)" "unprognostic (2.86e-3)" "unprognostic (8.23e-3)" "unprognostic (7.65e-2)" "unprognostic (2.51e-3)" "unprognostic (4.72e-3)" "potential prognostic unfavorable (7.19e-4)" "validated prognostic unfavorable (2.09e-4)" "validated prognostic unfavorable (8.34e-5)" "unprognostic (5.25e-3)" "unprognostic (1.87e-2)" "unprognostic (9.08e-2)" "unprognostic (1.89e-1)" "potential prognostic unfavorable (3.94e-4)" "unprognostic (4.88e-1)" "unprognostic (5.58e-2)" "unprognostic (1.86e-2)" "unprognostic (3.35e-2)" "unprognostic (5.00e-3)" "unprognostic (3.15e-1)" "unprognostic (3.37e-1)" "unprognostic (9.54e-2)" "unprognostic (1.10e-1)" MIS18BP1 "C14orf106, FLJ11186, KIAA1903, KNL2, M18BP1" ENSG00000129534 "MIS18 binding protein 1" Q6P0N0 14 45203190-45253540 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 38.5" "Cell type enhanced" "Detected in many" "Microglia: 315.4;Monocyte progenitors: 489.8;Neutrophil progenitors: 414.7" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 387.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA006504 Approved Approved Nucleoli,Cytosol NA Yes "Cluster 41: Basophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 16 Nucleoli Cytosol "HPA006504: " "unprognostic (6.84e-2)" "unprognostic (1.30e-1)" "unprognostic (9.73e-3)" "unprognostic (1.42e-1)" "unprognostic (1.95e-1)" "unprognostic (2.38e-1)" "unprognostic (1.42e-1)" "unprognostic (3.68e-2)" "unprognostic (4.02e-3)" "potential prognostic favorable (2.61e-5)" "unprognostic (7.24e-2)" "unprognostic (1.15e-1)" "potential prognostic unfavorable (3.11e-4)" "unprognostic (1.22e-1)" "unprognostic (1.28e-2)" "unprognostic (4.14e-3)" "unprognostic (9.86e-2)" "unprognostic (4.29e-1)" "unprognostic (1.73e-1)" "unprognostic (4.46e-1)" "unprognostic (1.51e-2)" "unprognostic (8.46e-3)" "unprognostic (1.61e-2)" "unprognostic (3.08e-2)" "unprognostic (6.59e-2)" "unprognostic (3.55e-2)" "unprognostic (1.96e-2)" "unprognostic (4.91e-1)" "unprognostic (7.65e-2)" "unprognostic (4.56e-2)" MISP "C19orf21, Caprice, DKFZp686H18209, MISP1" ENSG00000099812 "Mitotic spindle positioning" Q8IVT2 19 751112-764318 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "intestine: 185.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 116.6;Colonocytes: 703.5;Enteric stem cells: 135.8;Enteric transient amplifying cells: 190.7;Enterocytes: 1134.4;Fallopian tube ciliated cells: 126.0;Foveolar cells: 103.8;Goblet cells: 251.5;Paneth cells: 108.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 185.9;Rectum Adenocarcinoma (TCGA): 174.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 104.4" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Kidney - Proximal tubular cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA049511, HPA062232" Enhanced Enhanced "Plasma membrane,Focal adhesion sites" No No "Cluster 77: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 77 "Plasma membrane, Focal adhesion sites" "HPA049511: , HPA062232: " "unprognostic (1.62e-2)" "unprognostic (5.85e-2)" "unprognostic (9.27e-2)" "unprognostic (1.02e-1)" "unprognostic (1.89e-1)" "unprognostic (6.83e-2)" "unprognostic (7.81e-3)" "unprognostic (2.94e-1)" "unprognostic (2.24e-1)" "unprognostic (1.57e-2)" "potential prognostic unfavorable (2.69e-4)" "unprognostic (7.58e-2)" "unprognostic (1.37e-3)" "unprognostic (1.42e-1)" "unprognostic (1.07e-2)" "unprognostic (8.40e-2)" "unprognostic (2.15e-3)" "unprognostic (3.26e-2)" "unprognostic (2.35e-1)" "unprognostic (8.03e-3)" "unprognostic (5.34e-2)" "unprognostic (6.51e-3)" "unprognostic (1.43e-1)" "unprognostic (2.21e-1)" "unprognostic (1.89e-1)" MISP3 ENSG00000141854 "MISP family member 3" Q96FF7 19 14072536-14075062 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.1;kidney: 14.9" "Cell type enhanced" "Detected in some" "Bergmann glia: 8.0;Brain excitatory neurons: 14.4;Brain inhibitory neurons: 11.6;Ependymal cells: 18.0;Gastric chief cells: 24.0;Mucous neck cells: 9.0;Oligodendrocyte progenitor cells: 8.3;Oligodendrocytes: 11.8;Other brain neurons: 17.8;Platelets: 52.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "neutrophil: 1.0" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA042225 Uncertain NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" "HPA042225: " "unprognostic (3.65e-2)" "unprognostic (7.49e-2)" "unprognostic (2.12e-1)" "unprognostic (1.05e-1)" "unprognostic (3.16e-2)" "unprognostic (2.73e-2)" "unprognostic (3.47e-1)" "unprognostic (2.00e-1)" "unprognostic (3.18e-3)" "unprognostic (1.79e-1)" "potential prognostic favorable (4.09e-6)" "unprognostic (9.12e-2)" "unprognostic (6.36e-3)" "unprognostic (9.53e-3)" "unprognostic (2.07e-1)" "unprognostic (3.57e-3)" "potential prognostic favorable (4.23e-4)" "unprognostic (1.71e-1)" "unprognostic (1.32e-1)" "unprognostic (8.50e-3)" "unprognostic (3.66e-1)" "potential prognostic favorable (5.83e-6)" "unprognostic (2.77e-1)" "unprognostic (2.00e-1)" MITD1 LOC129531 ENSG00000158411 "Microtubule interacting and trafficking domain containing 1" Q8WV92 2 99161427-99181058 "Predicted intracellular proteins" "Cell cycle, Cell division, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036162, HPA036163" Approved Enhanced Vesicles NA NA "Cluster 18: Non-specific - Translation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 11: White matter - Signal transduction" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 7: Non-specific - Transcription" 15 Vesicles "HPA036162: , HPA036163: " "unprognostic (3.55e-1)" "unprognostic (6.26e-3)" "unprognostic (5.55e-2)" "unprognostic (1.87e-3)" "unprognostic (2.57e-1)" "unprognostic (1.51e-1)" "unprognostic (2.74e-2)" "unprognostic (4.90e-2)" "unprognostic (2.95e-3)" "potential prognostic unfavorable (5.85e-4)" "unprognostic (7.25e-2)" "unprognostic (2.41e-1)" "unprognostic (2.42e-2)" "potential prognostic unfavorable (7.10e-6)" "unprognostic (1.64e-3)" "unprognostic (1.82e-2)" "unprognostic (2.18e-2)" "unprognostic (7.21e-2)" "unprognostic (2.80e-1)" "unprognostic (3.34e-1)" "unprognostic (5.42e-2)" "unprognostic (9.11e-3)" "unprognostic (2.12e-3)" "unprognostic (6.88e-2)" "unprognostic (7.49e-2)" "unprognostic (1.38e-1)" "unprognostic (5.05e-2)" "unprognostic (2.13e-1)" "unprognostic (1.50e-1)" "unprognostic (4.50e-2)" "unprognostic (2.71e-2)" MITF "bHLHe32, MI, WS2, WS2A" ENSG00000187098 "Melanocyte inducing transcription factor" O75030 3 69739456-69968336 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Albinism, Cancer-related genes, Deafness, Disease variant, Microphthalmia, Osteopetrosis, Waardenburg syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 930.7;Choroid plexus epithelial cells: 450.0;Distal convoluted tubule cells: 815.4;Endometrial glandular cells: 560.2;Endometrial stromal cells: 444.6;Mast cells: 468.8;Melanocytes: 2101.2;Myonuclei: 576.9;Renal connecting tubule cells: 543.0;Retinal pigment epithelial cells: 584.0" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 511.7;oligodendrocyte: 408.6" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 98.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 5.9;classical monocyte: 10.3;intermediate monocyte: 3.6;myeloid DC: 6.5;non-classical monocyte: 6.0" "Group enriched" "Detected in many" 6 "dendritic cells: 6.5;granulocytes: 5.9;monocytes: 10.3" "Cancer enriched" "Detected in all" 7 "skin cancer: 152.5" "Adrenal gland - Adrenal cortex cells, Breast - Fibroblasts, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002578, HPA003259" Enhanced NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 61: Schwann cells & Melanocytes - Mixed function" 16 "CAB002578: , HPA003259: " "unprognostic (5.27e-3)" "unprognostic (1.15e-1)" "unprognostic (5.19e-2)" "unprognostic (5.35e-1)" "unprognostic (1.12e-1)" "unprognostic (9.34e-2)" "unprognostic (1.10e-1)" "unprognostic (1.94e-2)" "unprognostic (1.31e-1)" "unprognostic (8.96e-2)" "potential prognostic favorable (3.17e-6)" "unprognostic (3.22e-3)" "unprognostic (3.41e-2)" "unprognostic (6.23e-3)" "unprognostic (1.17e-1)" "unprognostic (2.92e-1)" "unprognostic (4.93e-3)" "unprognostic (1.05e-1)" "unprognostic (2.27e-1)" "unprognostic (2.50e-3)" "unprognostic (6.78e-2)" "unprognostic (1.11e-2)" "unprognostic (3.80e-2)" "unprognostic (4.76e-1)" "unprognostic (2.93e-2)" "unprognostic (6.81e-3)" "unprognostic (4.78e-2)" "unprognostic (3.33e-2)" "unprognostic (2.18e-1)" "unprognostic (1.05e-1)" "unprognostic (1.02e-1)" MIX23 "CCDC58, FLJ33273" ENSG00000160124 "Mitochondrial matrix import factor 23" Q4VC31 3 122359591-122383231 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal suprabasal cells: 71.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051965 Approved Approved Nucleoli,Mitochondria No No 22000 "Cluster 30: Non-specific - DNA binding" "Cluster 76: Non-specific - Metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 63: Non-specific - Protein processing" "Cluster 97: Non-specific - Cellular respiration" 5 Mitochondria Nucleoli "HPA051965: " "unprognostic (1.38e-1)" "unprognostic (5.17e-2)" "unprognostic (1.40e-1)" "unprognostic (3.08e-1)" "unprognostic (3.17e-2)" "unprognostic (1.04e-1)" "unprognostic (1.28e-1)" "unprognostic (1.05e-1)" "potential prognostic unfavorable (5.05e-4)" "potential prognostic unfavorable (1.35e-5)" "unprognostic (1.96e-1)" "unprognostic (1.62e-2)" "unprognostic (2.90e-2)" "validated prognostic unfavorable (1.32e-6)" "validated prognostic unfavorable (1.89e-4)" "potential prognostic unfavorable (3.33e-4)" "unprognostic (6.80e-3)" "unprognostic (6.26e-2)" "unprognostic (3.11e-1)" "unprognostic (2.58e-2)" "unprognostic (4.48e-2)" "validated prognostic unfavorable (5.97e-5)" "validated prognostic unfavorable (3.14e-4)" "unprognostic (4.07e-3)" "unprognostic (1.54e-1)" "unprognostic (2.78e-1)" "unprognostic (3.40e-3)" "unprognostic (6.11e-2)" "unprognostic (1.55e-1)" "unprognostic (8.51e-2)" "unprognostic (1.88e-1)" MIXL1 "MILD1, MIXL" ENSG00000185155 "Mix paired-like homeobox" Q9H2W2 1 226223618-226227060 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 3.2" "Group enriched" "Detected in some" 5 "Oocytes: 23.0;Plasma cells: 16.2" "Cell type enhanced" "Detected in single" "endothelial cell: 1.1" "Cancer enriched" "Detected in some" 8 "Testicular Germ Cell Tumor (TCGA): 11.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "lymphoma: 1.7;testis cancer: 1.7" "Adipose visceral - Mesothelial cells, Breast - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Stomach - Plasma cells, Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA005662 Approved Nucleoplasm NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 35: Non-specific - DNA binding" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 44: Plasma cells - Antibody production & secretion" Nucleoplasm "HPA005662: " "unprognostic (1.70e-1)" "unprognostic (1.60e-2)" "unprognostic (1.68e-1)" "unprognostic (2.83e-3)" "unprognostic (1.74e-1)" "unprognostic (2.02e-1)" "unprognostic (3.08e-2)" "unprognostic (1.17e-2)" MKI67 "Ki-67, MIB-1, PPP1R105" ENSG00000148773 "Marker of proliferation Ki-67" P46013 10 128096659-128126423 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 43.7;lymphoid tissue: 49.0" "Cell type enhanced" "Detected in many" "Enteric transient amplifying cells: 104.2;Erythrocyte progenitors: 369.6;Esophageal basal cells: 115.3;Extravillous trophoblasts: 100.0;Megakaryocyte progenitors: 312.5;Monocyte progenitors: 752.7;Neutrophil progenitors: 203.8;Plasma cells: 84.6" "Cell type enriched" "Detected in single" 6 "leukocyte: 2.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB000058, HPA000451, HPA001164, CAB068198, CAB080228" Enhanced Supported "Nucleoplasm,Nucleoli rim,Mitotic chromosome" Yes Yes "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 12: Non-specific - Vasculature" "Cluster 52: Non-specific - Mitochondria" "Cluster 27: Non-specific - Cell proliferation" 61 "Nucleoli rim" "Nucleoplasm, Mitotic chromosome" "CAB000058: , CAB068198: , CAB080228: , HPA000451: , HPA001164: " "unprognostic (5.51e-2)" "unprognostic (1.16e-1)" "unprognostic (3.60e-1)" "unprognostic (1.92e-1)" "unprognostic (1.37e-1)" "unprognostic (3.24e-1)" "unprognostic (5.37e-1)" "unprognostic (1.60e-1)" "unprognostic (7.49e-2)" "potential prognostic unfavorable (5.49e-5)" "potential prognostic unfavorable (3.53e-5)" "unprognostic (1.66e-3)" "potential prognostic unfavorable (1.62e-11)" "validated prognostic unfavorable (1.29e-5)" "validated prognostic unfavorable (6.56e-7)" "validated prognostic unfavorable (5.03e-5)" "validated prognostic unfavorable (4.94e-5)" "unprognostic (1.58e-1)" "unprognostic (1.50e-1)" "unprognostic (2.12e-1)" "unprognostic (2.14e-1)" "potential prognostic unfavorable (5.08e-5)" "unprognostic (1.91e-2)" "unprognostic (2.14e-2)" "unprognostic (1.63e-2)" "unprognostic (1.56e-2)" "unprognostic (4.98e-2)" "unprognostic (3.22e-2)" "unprognostic (2.21e-1)" "unprognostic (1.89e-1)" "unprognostic (4.76e-1)" MKKS BBS6 ENSG00000125863 "MKKS centrosomal shuttling protein" Q9NPJ1 20 10401009-10434222 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" Chaperone "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Intellectual disability, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 73.7;Late primary spermatocytes: 94.0;Parietal cells: 113.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041071, HPA044233" Enhanced Supported "Centrosome,Basal body" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 76: Non-specific - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 97: Non-specific - Cellular respiration" 6 "Centrosome, Basal body" "HPA041071: , HPA044233: " "unprognostic (8.50e-2)" "unprognostic (2.78e-3)" "unprognostic (1.36e-1)" "unprognostic (1.97e-2)" "unprognostic (1.05e-1)" "unprognostic (8.52e-2)" "unprognostic (9.38e-2)" "unprognostic (6.90e-2)" "unprognostic (1.40e-1)" "unprognostic (1.66e-1)" "potential prognostic favorable (2.30e-10)" "unprognostic (2.08e-3)" "unprognostic (1.41e-3)" "potential prognostic unfavorable (3.22e-4)" "unprognostic (1.94e-3)" "unprognostic (4.45e-2)" "unprognostic (2.18e-2)" "unprognostic (2.53e-1)" "unprognostic (2.04e-1)" "unprognostic (7.93e-2)" "unprognostic (2.80e-1)" "unprognostic (9.47e-3)" "unprognostic (5.57e-2)" "unprognostic (2.15e-1)" "unprognostic (8.48e-2)" "unprognostic (3.17e-1)" "unprognostic (2.58e-1)" "unprognostic (3.03e-2)" "unprognostic (1.07e-1)" "unprognostic (2.06e-2)" "unprognostic (2.11e-1)" MKKS ENSG00000285508 "MKKS centrosomal shuttling protein" 20 10413520-10431922 "Human disease related genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 35: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "potential prognostic unfavorable (4.85e-5)" "unprognostic (3.27e-1)" "unprognostic (3.84e-1)" "unprognostic (2.86e-1)" "potential prognostic unfavorable (2.22e-5)" "unprognostic (3.56e-2)" "potential prognostic unfavorable (1.26e-6)" "unprognostic (3.99e-3)" "unprognostic (7.70e-3)" "potential prognostic unfavorable (2.58e-4)" "potential prognostic unfavorable (4.63e-4)" "unprognostic (3.76e-1)" "unprognostic (2.23e-1)" "unprognostic (5.32e-2)" "unprognostic (8.07e-2)" "unprognostic (2.21e-3)" "unprognostic (8.44e-2)" "unprognostic (3.56e-1)" "unprognostic (1.52e-1)" "unprognostic (8.08e-2)" "unprognostic (1.37e-1)" "unprognostic (1.51e-1)" MKKS ENSG00000285723 "MKKS centrosomal shuttling protein" 20 10420546-10420737 "Human disease related genes, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "unprognostic (1.22e-1)" "unprognostic (3.35e-2)" "potential prognostic unfavorable (4.97e-5)" "unprognostic (3.66e-1)" "unprognostic (1.86e-3)" "unprognostic (6.78e-2)" "unprognostic (2.32e-3)" "unprognostic (8.72e-3)" "potential prognostic favorable (6.45e-4)" "unprognostic (4.57e-2)" "unprognostic (1.57e-1)" "potential prognostic unfavorable (1.96e-4)" "unprognostic (7.45e-3)" "unprognostic (1.19e-1)" "unprognostic (4.41e-2)" "unprognostic (1.57e-1)" "unprognostic (1.08e-2)" "unprognostic (1.92e-1)" "unprognostic (4.45e-2)" "unprognostic (1.12e-1)" "unprognostic (3.03e-1)" "unprognostic (1.13e-1)" "unprognostic (2.55e-1)" "unprognostic (9.40e-2)" "unprognostic (1.65e-1)" MKLN1 TWA2 ENSG00000128585 "Muskelin 1" Q9UL63 7 131110096-131496632 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 9.5" "Lineage enriched" "Detected in many" 6 "granulocytes: 9.5" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022817, HPA041810" Approved Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 44: Non-specific - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 24: Neutrophils - Innate immunity signal integration" 68 "Plasma membrane, Cytosol" Vesicles "HPA022817: , HPA041810: " "unprognostic (2.66e-2)" "unprognostic (1.05e-1)" "unprognostic (2.34e-1)" "potential prognostic unfavorable (4.65e-4)" "unprognostic (2.61e-2)" "unprognostic (3.43e-2)" "unprognostic (1.89e-1)" "unprognostic (9.74e-2)" "unprognostic (2.41e-2)" "unprognostic (7.15e-3)" "potential prognostic favorable (3.05e-7)" "unprognostic (9.70e-3)" "unprognostic (2.40e-1)" "unprognostic (1.38e-3)" "unprognostic (3.09e-1)" "unprognostic (5.66e-3)" "unprognostic (1.13e-2)" "unprognostic (1.68e-1)" "unprognostic (1.23e-1)" "unprognostic (8.14e-2)" "unprognostic (5.64e-3)" "unprognostic (7.16e-3)" "unprognostic (2.26e-3)" "unprognostic (2.71e-1)" "unprognostic (1.59e-1)" "unprognostic (1.63e-1)" "unprognostic (4.01e-2)" "unprognostic (1.17e-1)" "unprognostic (1.14e-1)" "unprognostic (9.55e-2)" "unprognostic (3.11e-1)" MKNK1 MNK1 ENSG00000079277 "MAPK interacting serine/threonine kinase 1" Q9BUB5 1 46557407-46616843 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Translation regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 112.4" "Cell type enhanced" "Detected in all" "Hofbauer cells: 367.7;Kupffer cells: 192.7;Microglia: 365.3;Neutrophils: 590.9" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 411.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB027355, CAB037310, HPA071293" Approved Supported Nucleoplasm NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 8: Pancreas - Proteolysis" "Cluster 48: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 24: Neutrophils - Innate immunity signal integration" 16 Nucleoplasm "CAB027355: , CAB037310: , HPA071293: " "unprognostic (2.55e-1)" "unprognostic (1.18e-1)" "unprognostic (1.00e-1)" "unprognostic (9.54e-2)" "unprognostic (1.16e-1)" "unprognostic (1.31e-1)" "unprognostic (2.94e-1)" "unprognostic (1.50e-2)" "unprognostic (2.05e-2)" "unprognostic (1.45e-2)" "unprognostic (9.39e-3)" "unprognostic (1.81e-1)" "unprognostic (5.36e-2)" "potential prognostic unfavorable (4.36e-5)" "unprognostic (6.90e-2)" "unprognostic (1.50e-1)" "unprognostic (1.05e-2)" "unprognostic (2.30e-1)" "unprognostic (3.46e-1)" "unprognostic (2.87e-2)" "unprognostic (1.58e-1)" "unprognostic (1.23e-2)" "unprognostic (2.46e-2)" "unprognostic (1.26e-1)" "unprognostic (3.12e-1)" "potential prognostic favorable (7.36e-4)" "unprognostic (3.63e-1)" "unprognostic (4.35e-2)" "unprognostic (1.15e-1)" "unprognostic (7.40e-2)" "unprognostic (1.63e-1)" MKNK2 "GPRK7, MNK2" ENSG00000099875 "MAPK interacting serine/threonine kinase 2" Q9HBH9 19 2037465-2051244 "Enzymes, Predicted intracellular proteins" "Apoptosis, Translation regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 1308.2" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 726.9;Esophageal suprabasal cells: 320.3;Neutrophils: 272.1;Pancreatic acinar cells: 296.4;Thymic myoid cells: 282.8" "Cell type enhanced" "Detected in all" "endothelial cell: 60.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021875, CAB037253, HPA070499" Supported Supported "Nucleoplasm,Nuclear bodies,Cytosol" No No "Cluster 20: Non-specific - DNA binding" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 25: Non-specific - Transcription" "Cluster 55: Lymphoma - Immune response" "Cluster 20: Non-specific - Transcription regulation" 7 "Nuclear bodies" "Nucleoplasm, Cytosol" "CAB037253: , HPA021875: , HPA070499: " "unprognostic (5.60e-2)" "unprognostic (1.44e-1)" "unprognostic (5.86e-2)" "unprognostic (2.21e-1)" "unprognostic (2.37e-1)" "unprognostic (1.58e-3)" "unprognostic (1.70e-1)" "unprognostic (2.16e-1)" "unprognostic (5.87e-2)" "unprognostic (1.17e-1)" "unprognostic (1.10e-1)" "potential prognostic favorable (6.79e-4)" "unprognostic (1.11e-1)" "potential prognostic unfavorable (3.13e-6)" "unprognostic (8.95e-2)" "unprognostic (7.21e-2)" "unprognostic (2.22e-2)" "unprognostic (4.29e-2)" "unprognostic (5.98e-2)" "unprognostic (1.15e-1)" "unprognostic (2.84e-1)" "unprognostic (6.23e-2)" "unprognostic (7.20e-2)" "potential prognostic unfavorable (3.79e-4)" "unprognostic (1.94e-1)" "unprognostic (2.21e-1)" "unprognostic (2.33e-1)" "potential prognostic favorable (9.22e-4)" "unprognostic (4.25e-2)" "unprognostic (1.94e-1)" "unprognostic (4.17e-2)" MKRN1 RNF61 ENSG00000133606 "Makorin ring finger protein 1" Q9UHC7 7 140453033-140479536 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythrocytes: 411.5;Late primary spermatocytes: 662.7;Late spermatids: 509.7;Platelets: 409.0" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 4 "Testicular Germ Cell Tumor (TCGA): 421.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000567 Approved Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 39: Non-specific - Transcription" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 36 "Nucleoplasm, Cytosol" "HPA000567: " "unprognostic (1.92e-1)" "unprognostic (2.29e-1)" "unprognostic (2.62e-1)" "unprognostic (9.13e-2)" "unprognostic (2.34e-1)" "unprognostic (1.05e-1)" "unprognostic (2.73e-2)" "unprognostic (8.66e-2)" "unprognostic (2.21e-1)" "unprognostic (7.39e-2)" "validated prognostic favorable (4.14e-7)" "validated prognostic favorable (8.19e-4)" "unprognostic (2.24e-1)" "unprognostic (1.39e-2)" "potential prognostic unfavorable (1.17e-4)" "unprognostic (6.12e-2)" "unprognostic (5.18e-2)" "unprognostic (7.48e-2)" "unprognostic (1.70e-1)" "unprognostic (3.10e-2)" "potential prognostic unfavorable (6.79e-4)" "unprognostic (4.54e-2)" "unprognostic (9.36e-2)" "unprognostic (8.88e-2)" "unprognostic (1.16e-1)" "unprognostic (4.62e-2)" "unprognostic (3.97e-2)" "unprognostic (1.07e-2)" "unprognostic (3.47e-1)" "unprognostic (6.84e-2)" "unprognostic (1.29e-1)" MKRN2 "HSPC070, RNF62" ENSG00000075975 "Makorin ring finger protein 2" Q9H000 3 12557057-12586208 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 722.3;Late spermatids: 1168.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037559, HPA037560" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 61: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 36 "Nucleoplasm, Cytosol" "HPA037559: , HPA037560: " "unprognostic (5.57e-2)" "unprognostic (5.95e-2)" "unprognostic (4.21e-2)" "unprognostic (5.05e-2)" "unprognostic (1.92e-1)" "unprognostic (1.57e-1)" "unprognostic (6.43e-2)" "unprognostic (1.76e-1)" "unprognostic (8.61e-2)" "unprognostic (4.68e-3)" "potential prognostic favorable (1.65e-5)" "unprognostic (2.31e-2)" "unprognostic (1.31e-1)" "potential prognostic unfavorable (3.06e-5)" "unprognostic (2.06e-2)" "unprognostic (1.86e-2)" "unprognostic (2.65e-2)" "unprognostic (1.47e-1)" "unprognostic (7.37e-2)" "unprognostic (9.14e-2)" "unprognostic (4.35e-2)" "unprognostic (4.67e-2)" "unprognostic (9.70e-2)" "unprognostic (2.35e-2)" "unprognostic (1.75e-2)" "unprognostic (1.22e-1)" "unprognostic (3.83e-1)" "unprognostic (2.77e-1)" "unprognostic (2.81e-2)" "unprognostic (5.85e-2)" "unprognostic (2.76e-1)" MKRN2OS "C3orf83, MKRN2-AS1" ENSG00000225526 "MKRN2 opposite strand" H3BPM6 3 12514934-12561059 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 9.4" "Cell type enhanced" "Detected in many" "Adipocytes: 156.3;Cardiomyocytes: 266.7;Epicardial cells: 88.7;Esophageal apical cells: 61.1;Myonuclei: 61.0;Retinal ganglion cells: 54.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 6.3" "Breast - Breast glandular cells, Pituitary gland - Somatotropes, Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA065586, HPA065753" Uncertain Approved "Golgi apparatus" NA NA "Cluster 17: Intestine - Digestion" "Cluster 2: Neurons - Nucleosome" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 89: Adipocytes - Lipid metabolism" "Golgi apparatus" "HPA065586: , HPA065753: " "unprognostic (5.33e-2)" "unprognostic (1.21e-1)" "unprognostic (8.16e-2)" "unprognostic (9.22e-2)" "unprognostic (1.51e-1)" "unprognostic (2.37e-1)" "unprognostic (2.49e-2)" "unprognostic (1.32e-1)" "unprognostic (2.97e-2)" "unprognostic (1.42e-1)" "potential prognostic unfavorable (3.97e-4)" "unprognostic (1.48e-2)" "unprognostic (1.47e-2)" "unprognostic (2.25e-2)" "unprognostic (1.37e-2)" "unprognostic (2.25e-1)" "unprognostic (3.05e-2)" "unprognostic (1.83e-1)" MKRN3 "D15S9, MGC88288, RNF63, ZFP127, ZNF127" ENSG00000179455 "Makorin ring finger protein 3" Q13064 15 23565674-23630075 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.1;retina: 8.2" "Cell type enhanced" "Detected in some" "Astrocytes: 89.9;Bergmann glia: 72.0;Choroid plexus epithelial cells: 33.4;Ependymal cells: 60.3;Oligodendrocyte progenitor cells: 152.3;Oligodendrocytes: 195.8" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 162.2;oligodendrocyte: 239.6;oligodendrocyte precursor cell: 164.3" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 6.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD8 T-cell: 2.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA029494 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 59: Leukemia - T-cell receptor" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 136 "Plasma membrane, Cytosol" Nucleoplasm "HPA029494: " "unprognostic (8.06e-3)" "unprognostic (7.47e-2)" "unprognostic (5.44e-1)" "unprognostic (1.56e-1)" "unprognostic (2.29e-2)" "unprognostic (1.19e-2)" "potential prognostic favorable (4.08e-4)" "unprognostic (6.05e-3)" "unprognostic (6.30e-3)" "unprognostic (1.29e-1)" "unprognostic (1.61e-2)" "unprognostic (8.25e-2)" "unprognostic (5.31e-3)" "unprognostic (1.89e-1)" "potential prognostic unfavorable (2.52e-4)" "unprognostic (3.04e-2)" "unprognostic (1.33e-1)" "unprognostic (6.69e-2)" "unprognostic (3.37e-2)" "unprognostic (1.04e-1)" "unprognostic (1.83e-1)" "unprognostic (2.34e-2)" MKS1 "BBS13, FLJ20345, MKS, POC12" ENSG00000011143 "MKS transition zone complex subunit 1" Q9NXB0 17 58205441-58219605 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Cilium biogenesis/degradation" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Intellectual disability, Joubert syndrome, Meckel syndrome, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Respiratory ciliated cells: 46.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021372, HPA021812" Enhanced Approved "Nucleoplasm,Nucleoli,Basal body" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Breast cancer - Unknown function" "Cluster 107: Ciliated cells - Cilia assembly & function" 23 "Nucleoplasm, Nucleoli, Basal body" "HPA021372: , HPA021812: " "unprognostic (7.77e-3)" "unprognostic (9.10e-2)" "unprognostic (5.39e-3)" "unprognostic (5.61e-2)" "unprognostic (1.73e-2)" "unprognostic (5.75e-2)" "unprognostic (2.64e-1)" "unprognostic (2.99e-3)" "unprognostic (1.51e-1)" "unprognostic (3.59e-2)" "unprognostic (1.06e-3)" "unprognostic (1.76e-1)" "unprognostic (6.58e-3)" "unprognostic (1.45e-3)" "unprognostic (4.57e-3)" "unprognostic (5.23e-1)" "unprognostic (4.24e-2)" "unprognostic (2.37e-1)" "unprognostic (1.35e-2)" "unprognostic (1.20e-1)" "unprognostic (2.65e-1)" "unprognostic (1.64e-1)" "unprognostic (1.95e-2)" "unprognostic (1.77e-1)" "unprognostic (5.87e-3)" "unprognostic (1.08e-2)" "unprognostic (1.08e-1)" "unprognostic (2.93e-2)" "unprognostic (2.61e-1)" "unprognostic (3.72e-1)" "unprognostic (1.04e-1)" MKX "C10orf48, IRXL1, MGC39616" ENSG00000150051 "Mohawk homeobox" Q8IYA7 10 27672874-27746060 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 10.6;prostate: 14.7" "Cell type enriched" "Detected in many" 4 "Gonadotrophs: 558.1" "Cell type enhanced" "Detected in many" "ependymal cell: 105.5;mammillary body: 121.1" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 6.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Fibroblasts, Spleen - Smooth muscle cells, Testis - Peritubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006927 Uncertain Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 4 "Nucleoplasm, Nuclear speckles" "HPA006927: " "unprognostic (1.78e-1)" "unprognostic (2.75e-1)" "unprognostic (7.71e-3)" "unprognostic (1.65e-2)" "unprognostic (1.82e-1)" "unprognostic (2.12e-2)" "unprognostic (6.02e-2)" "unprognostic (8.50e-2)" "unprognostic (3.02e-2)" "unprognostic (1.16e-1)" "unprognostic (1.08e-1)" "unprognostic (4.31e-2)" "unprognostic (9.27e-2)" "unprognostic (1.39e-2)" "unprognostic (1.29e-1)" "unprognostic (8.30e-2)" "unprognostic (9.71e-2)" MLANA "MART-1, MART1" ENSG00000120215 Melan-A Q16655 9 5890889-5910606 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 30 "skin 1: 40.6" "Cell type enriched" "Detected in many" 31 "Melanocytes: 2723.9" "Cell type enriched" "Detected in all" 4 "choroid plexus epithelial cell: 31.2" "Cancer enriched" "Detected in some" 600 "Skin Cutaneous Melanoma (TCGA): 1242.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 57 "skin cancer: 399.2" "Skin - Melanocytes" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB000057, HPA048662" Enhanced NA NA "Cluster 37: Skin - Keratinization" "Cluster 6: Non-specific - Immune response" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 61: Schwann cells & Melanocytes - Mixed function" 7 "CAB000057: , HPA048662: " "unprognostic (4.95e-2)" "unprognostic (1.05e-1)" "unprognostic (1.37e-1)" "unprognostic (2.40e-1)" "unprognostic (1.18e-1)" "unprognostic (1.16e-1)" "unprognostic (1.00e-1)" MLC1 "KIAA0027, LVM, MLC, VL" ENSG00000100427 "Modulator of VRAC current 1" Q15049 22 50059391-50085426 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 231.9" "Cell type enhanced" "Detected in many" "Astrocytes: 156.0;Bergmann glia: 154.6;Ependymal cells: 154.5;Hematopoietic stem cells: 30.1;Megakaryocyte progenitors: 68.3;Megakaryocyte-Erythroid progenitors: 46.6;Megakaryocytes: 30.9;Neutrophil progenitors: 44.4;NK-cells: 34.5;Platelets: 42.2;Thymocytes: 44.0" "Group enriched" "Detected in many" 9 "astrocyte: 160.8;Bergmann glia: 154.2;ependymal cell: 178.9" "Cancer enriched" "Detected in some" 72 "Glioblastoma Multiforme (TCGA): 232.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 20.2" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 6 "Leukemia: 65.7;Myeloma: 63.1" "Liver - NK-cells (Liver), Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003040 Enhanced Supported Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 78: Brain - Neuronal signaling" "Cluster 39: Astrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 28: Astrocytes - Homeostasis & neuron support" 14 Cytosol "HPA003040: " "unprognostic (3.17e-2)" "unprognostic (2.02e-1)" "unprognostic (1.25e-1)" "unprognostic (1.21e-2)" "unprognostic (8.63e-2)" "unprognostic (2.73e-1)" "unprognostic (2.84e-1)" "unprognostic (2.58e-1)" MLEC KIAA0152 ENSG00000110917 Malectin Q14165 12 120687149-120701859 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epididymal principal cells: 394.3;Melanocytes: 433.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 510000 "Cluster 29: Non-specific - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 46: Brainstem - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 29 "unprognostic (8.15e-2)" "unprognostic (3.02e-2)" "unprognostic (2.77e-1)" "unprognostic (7.28e-2)" "unprognostic (6.45e-3)" "unprognostic (1.15e-2)" "unprognostic (2.31e-1)" "unprognostic (1.06e-2)" "unprognostic (1.72e-1)" "unprognostic (1.40e-2)" "potential prognostic favorable (3.71e-4)" "unprognostic (6.43e-2)" "unprognostic (1.52e-1)" "unprognostic (5.81e-2)" "potential prognostic unfavorable (2.36e-4)" "unprognostic (9.90e-2)" "unprognostic (2.30e-1)" "unprognostic (2.30e-1)" "unprognostic (1.06e-1)" "unprognostic (2.37e-2)" "unprognostic (1.41e-2)" "unprognostic (9.16e-2)" "unprognostic (7.69e-3)" "unprognostic (1.46e-1)" "unprognostic (3.01e-1)" "unprognostic (3.07e-2)" "unprognostic (2.27e-2)" "unprognostic (1.07e-1)" "unprognostic (1.57e-1)" "unprognostic (2.47e-2)" "unprognostic (6.69e-2)" MLF1 ENSG00000178053 "Myeloid leukemia factor 1" P58340 3 158571163-158607252 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cell cycle, Differentiation" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 170.9;testis: 340.3" "Group enriched" "Detected in many" 4 "Early spermatids: 5554.7;Late spermatids: 19791.8" "Cell type enhanced" "Detected in all" "ependymal cell: 307.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 8.8" "Lineage enriched" "Detected in single" 9 "T-cells: 8.8" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017852, HPA079339" Enhanced Approved "Nucleoplasm,Vesicles,Plasma membrane,Focal adhesion sites,Centrosome,Basal body,Cytosol,Mid piece,Principal piece,End piece" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 63: Non-specific - Protein processing" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 31 "Nucleoplasm, Centrosome, Basal body, Mid piece, Principal piece, End piece" "Vesicles, Plasma membrane, Focal adhesion sites, Cytosol" "HPA017852: , HPA079339: " "unprognostic (1.14e-1)" "unprognostic (1.32e-1)" "unprognostic (1.36e-2)" "unprognostic (6.88e-3)" "unprognostic (2.02e-2)" "potential prognostic favorable (6.54e-4)" "unprognostic (3.82e-3)" "unprognostic (1.95e-3)" "unprognostic (4.38e-2)" "unprognostic (1.83e-2)" "unprognostic (1.04e-2)" "unprognostic (2.16e-1)" "unprognostic (2.03e-1)" "unprognostic (2.41e-2)" "unprognostic (5.84e-3)" "unprognostic (6.26e-2)" "unprognostic (1.78e-2)" "unprognostic (1.73e-1)" "unprognostic (2.07e-1)" "unprognostic (3.51e-1)" "unprognostic (1.86e-1)" "unprognostic (1.88e-1)" "unprognostic (2.29e-2)" "unprognostic (1.41e-1)" "unprognostic (2.15e-1)" "unprognostic (3.05e-2)" "unprognostic (1.67e-1)" "unprognostic (2.19e-2)" "unprognostic (8.06e-3)" "unprognostic (4.29e-3)" "unprognostic (3.54e-2)" MLF2 NTN4 ENSG00000089693 "Myeloid leukemia factor 2" Q15773 12 6747996-6767475 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 378.0;Syncytiotrophoblasts: 489.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010811, HPA010859" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA Yes "Cluster 29: Non-specific - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 14: Neurons - Synaptic function" "Cluster 38: Non-specific - Transcription" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 41 Nucleoplasm "Plasma membrane, Cytosol" "HPA010811: , HPA010859: " "unprognostic (6.06e-2)" "unprognostic (1.50e-1)" "unprognostic (1.37e-1)" "unprognostic (1.01e-1)" "unprognostic (3.18e-2)" "unprognostic (7.61e-2)" "unprognostic (1.99e-1)" "unprognostic (8.06e-3)" "unprognostic (2.92e-2)" "unprognostic (9.85e-3)" "unprognostic (2.03e-1)" "unprognostic (3.76e-3)" "unprognostic (1.93e-1)" "unprognostic (1.31e-2)" "unprognostic (4.98e-3)" "unprognostic (2.09e-3)" "unprognostic (1.28e-1)" "unprognostic (5.22e-2)" "unprognostic (1.58e-1)" "unprognostic (2.83e-1)" "unprognostic (1.17e-1)" "unprognostic (3.39e-1)" "unprognostic (1.02e-2)" "unprognostic (7.04e-2)" "unprognostic (2.51e-1)" "unprognostic (2.51e-2)" "unprognostic (2.30e-1)" "unprognostic (8.06e-3)" "unprognostic (3.29e-1)" "unprognostic (9.27e-2)" "unprognostic (1.43e-1)" MLH1 "COCA2, FCC2, HNPCC, HNPCC2, MLH-1" ENSG00000076242 "MutL homolog 1" P40692 3 36993350-37050846 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013294, HPA052707, HPA060714, CAB070868" Supported Enhanced Nucleoplasm NA NA 3800 "Cluster 25: Non-specific - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 55: Non-specific - Transcription" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Transcription" 138 Nucleoplasm "CAB013294: , CAB070868: , HPA052707: , HPA060714: " "unprognostic (8.26e-2)" "unprognostic (5.06e-2)" "unprognostic (1.95e-1)" "unprognostic (1.81e-3)" "unprognostic (7.12e-2)" "unprognostic (1.59e-1)" "unprognostic (7.25e-2)" "unprognostic (1.11e-1)" "unprognostic (4.56e-1)" "unprognostic (3.20e-2)" "potential prognostic favorable (1.62e-7)" "unprognostic (8.26e-2)" "potential prognostic favorable (9.01e-4)" "unprognostic (1.12e-2)" "unprognostic (6.41e-3)" "unprognostic (4.71e-2)" "unprognostic (2.57e-2)" "unprognostic (1.81e-1)" "unprognostic (1.73e-2)" "unprognostic (3.34e-1)" "unprognostic (1.14e-1)" "unprognostic (2.66e-1)" "unprognostic (2.23e-2)" "unprognostic (6.35e-2)" "unprognostic (8.38e-2)" "unprognostic (6.12e-3)" "unprognostic (8.11e-2)" "unprognostic (1.10e-2)" "unprognostic (2.09e-1)" "unprognostic (8.46e-2)" "unprognostic (3.41e-1)" MLH3 ENSG00000119684 "MutL homolog 3" Q9UHC1 14 75013769-75051532 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Disease variant, Hereditary nonpolyposis colorectal cancer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Platelets: 344.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060570 Approved Nucleoplasm NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 47: Platelets - Hemostasis" 6 Nucleoplasm "HPA060570: " "unprognostic (2.02e-1)" "unprognostic (2.34e-1)" "unprognostic (9.88e-2)" "unprognostic (3.34e-1)" "unprognostic (1.42e-1)" "unprognostic (2.09e-3)" "unprognostic (1.35e-1)" "unprognostic (7.41e-2)" "unprognostic (1.94e-1)" "potential prognostic unfavorable (5.25e-5)" "potential prognostic favorable (3.78e-10)" "unprognostic (2.56e-3)" "unprognostic (8.71e-2)" "unprognostic (1.12e-2)" "unprognostic (3.90e-2)" "unprognostic (3.68e-1)" "unprognostic (4.12e-2)" "unprognostic (3.04e-2)" "unprognostic (7.73e-2)" "unprognostic (3.08e-2)" "unprognostic (5.88e-2)" "unprognostic (8.59e-2)" "unprognostic (1.09e-1)" "unprognostic (1.33e-1)" "unprognostic (3.05e-1)" "unprognostic (6.31e-3)" "unprognostic (1.26e-2)" "unprognostic (2.75e-1)" "unprognostic (1.43e-1)" "unprognostic (3.57e-1)" "unprognostic (6.55e-2)" MLIP "C6orf142, CIP, MGC18257" ENSG00000146147 "Muscular LMNA interacting protein" Q5VWP3 6 53929982-54266280 "Disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "heart muscle: 186.2;liver: 119.5;skeletal muscle: 205.1;tongue: 139.5" "Group enriched" "Detected in many" 12 "Cardiomyocytes: 2539.9;Myonuclei: 3506.9;Thymic myoid cells: 4190.4" "Cell type enhanced" "Detected in many" "deep-layer corticothalamic and 6b: 459.2;miscellaneous: 429.2;upper-layer intratelencephalic: 657.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 16.9;skin cancer: 10.3" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Pancreas - Alpha cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029252, HPA046654, HPA077663" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 41: Striated muscle - Muscle contraction" "Cluster 53: Neurons - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 1 "Nucleoplasm, Plasma membrane" Vesicles "HPA029252: , HPA046654: , HPA077663: " "unprognostic (3.89e-2)" "unprognostic (6.07e-3)" "potential prognostic favorable (1.68e-4)" "unprognostic (2.74e-2)" "unprognostic (1.18e-3)" "unprognostic (7.03e-2)" "unprognostic (1.81e-2)" "potential prognostic favorable (6.67e-5)" "unprognostic (7.77e-3)" "potential prognostic favorable (4.98e-5)" "unprognostic (3.26e-2)" "unprognostic (3.02e-3)" "unprognostic (2.56e-3)" "unprognostic (1.74e-1)" "unprognostic (7.83e-2)" "unprognostic (6.34e-2)" "unprognostic (5.32e-2)" "unprognostic (2.16e-2)" "unprognostic (3.87e-2)" "unprognostic (4.28e-2)" MLKL FLJ34389 ENSG00000168404 "Mixed lineage kinase domain like pseudokinase" Q8NB16 16 74671855-74700960 "Enzymes, Predicted intracellular proteins, Transporters" Necrosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hofbauer cells: 37.5;Macrophages: 46.9;Monocyte progenitors: 54.3;monocytes: 69.4;Neutrophil progenitors: 74.8;Neutrophils: 118.8;Plasma cells: 58.0;Vascular endothelial cells: 69.7" "Group enriched" "Detected in some" 4 "central nervous system macrophage: 32.7;endothelial cell: 57.5;leukocyte: 28.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells, Pituitary gland - Endothelial cells, Skeletal muscle - Endothelial cells, Testis - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA078638 Supported "Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 4 "Plasma membrane" "Cell Junctions, Cytosol" "HPA078638: " "unprognostic (1.15e-1)" "unprognostic (2.76e-1)" "potential prognostic favorable (5.44e-4)" "unprognostic (5.85e-3)" "unprognostic (1.84e-1)" "unprognostic (4.88e-2)" "unprognostic (6.53e-3)" "unprognostic (1.11e-1)" "unprognostic (4.82e-1)" "unprognostic (1.39e-1)" "unprognostic (7.01e-3)" "unprognostic (7.01e-2)" "unprognostic (1.75e-2)" "unprognostic (3.67e-2)" "unprognostic (1.70e-1)" "potential prognostic unfavorable (5.61e-4)" "unprognostic (7.30e-2)" "unprognostic (5.03e-2)" "unprognostic (1.29e-1)" "unprognostic (1.40e-1)" "unprognostic (1.05e-1)" "unprognostic (5.94e-2)" "potential prognostic unfavorable (3.47e-5)" "unprognostic (3.29e-1)" "unprognostic (1.37e-2)" "unprognostic (1.37e-1)" "unprognostic (2.53e-1)" "unprognostic (2.52e-1)" "unprognostic (1.52e-2)" "unprognostic (3.36e-1)" "unprognostic (4.89e-2)" MLLT1 "ENL, LTG19, YEATS1" ENSG00000130382 "MLLT1 super elongation complex subunit" Q03111 19 6210381-6279975 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 697.4;Migrating cytotrophoblasts: 328.0;Syncytiotrophoblasts: 1341.2" "Cell type enhanced" "Detected in all" "ependymal cell: 139.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031166 Approved Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 23: Non-specific - Transcription" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 34 Nucleoplasm "Nucleoli fibrillar center" "HPA031166: " "potential prognostic favorable (3.56e-4)" "unprognostic (8.96e-2)" "unprognostic (5.38e-2)" "unprognostic (3.13e-1)" "unprognostic (3.70e-1)" "unprognostic (3.01e-1)" "unprognostic (3.36e-1)" "unprognostic (1.65e-1)" "unprognostic (1.10e-3)" "unprognostic (7.88e-2)" "unprognostic (1.28e-2)" "unprognostic (1.84e-1)" "unprognostic (1.62e-1)" "unprognostic (5.83e-3)" "unprognostic (1.08e-1)" "unprognostic (9.25e-2)" "unprognostic (6.33e-2)" "unprognostic (1.88e-1)" "unprognostic (2.18e-2)" "unprognostic (3.15e-1)" "unprognostic (1.43e-2)" "unprognostic (2.17e-2)" "unprognostic (1.05e-2)" "unprognostic (3.41e-2)" "unprognostic (3.46e-2)" "unprognostic (1.26e-3)" "unprognostic (2.35e-2)" "unprognostic (1.33e-2)" "unprognostic (8.32e-2)" "unprognostic (3.89e-3)" "unprognostic (3.47e-3)" MLLT10 AF10 ENSG00000078403 "MLLT10 histone lysine methyltransferase DOT1L cofactor" P55197 10 21524646-21743630 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 86.9" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005736, HPA005747, HPA072790" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 39: Testis - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 7: Non-specific - Transcription" 15 Nucleoplasm Cytosol "HPA005736: , HPA005747: , HPA072790: " "unprognostic (3.65e-1)" "unprognostic (1.96e-1)" "unprognostic (1.38e-1)" "unprognostic (1.15e-1)" "unprognostic (5.38e-2)" "unprognostic (1.67e-1)" "unprognostic (9.20e-2)" "unprognostic (7.21e-3)" "unprognostic (4.53e-2)" "unprognostic (3.84e-1)" "potential prognostic favorable (2.22e-4)" "unprognostic (2.43e-2)" "unprognostic (2.36e-1)" "potential prognostic unfavorable (5.83e-6)" "unprognostic (1.10e-2)" "unprognostic (2.11e-2)" "unprognostic (2.80e-1)" "unprognostic (8.50e-2)" "unprognostic (4.26e-2)" "unprognostic (9.84e-2)" "potential prognostic unfavorable (7.97e-5)" "unprognostic (2.12e-1)" "potential prognostic unfavorable (5.22e-5)" "unprognostic (5.47e-2)" "unprognostic (1.92e-3)" "unprognostic (4.69e-2)" "unprognostic (1.28e-1)" "unprognostic (2.54e-1)" "unprognostic (2.50e-1)" "unprognostic (1.44e-1)" "unprognostic (6.77e-2)" MLLT11 AF1Q ENSG00000213190 "MLLT11 transcription factor 7 cofactor" Q13015 1 151060397-151069544 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 131.5" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 58.3;Brain inhibitory neurons: 45.9;Early spermatids: 94.2;Late spermatids: 364.6;Other brain neurons: 76.3;Smooth muscle cells: 43.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 79.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Neuroblastoma: 257.8" "Colon - Colon enteroendocrine cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000540 Uncertain Supported Nucleoplasm,Cytosol No No "Cluster 24: Non-specific - Transcription" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 103: Non-specific - Basic cellular processes" 5 "Nucleoplasm, Cytosol" "HPA000540: " "unprognostic (7.41e-2)" "unprognostic (8.63e-2)" "unprognostic (2.00e-1)" "unprognostic (2.73e-2)" "unprognostic (6.41e-3)" "unprognostic (2.10e-1)" "unprognostic (9.82e-2)" "unprognostic (3.09e-3)" "unprognostic (6.87e-3)" "unprognostic (1.66e-1)" "potential prognostic unfavorable (7.69e-9)" "unprognostic (4.69e-3)" "potential prognostic unfavorable (8.86e-7)" "unprognostic (2.35e-2)" "unprognostic (6.53e-3)" "unprognostic (1.17e-1)" "unprognostic (1.66e-1)" "unprognostic (5.90e-2)" "unprognostic (5.14e-2)" "unprognostic (7.08e-2)" "unprognostic (8.59e-2)" "unprognostic (3.58e-1)" "unprognostic (2.22e-2)" "unprognostic (8.21e-2)" "unprognostic (5.87e-2)" "unprognostic (3.46e-2)" "unprognostic (6.41e-2)" "unprognostic (3.61e-3)" "unprognostic (1.58e-1)" "unprognostic (3.20e-1)" "unprognostic (2.39e-1)" MLLT3 "AF-9, AF9, YEATS3" ENSG00000171843 "MLLT3 super elongation complex subunit" P42568 9 20341669-20622499 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hematopoietic stem cells: 596.8;Pituitary stem cells: 751.1;Renal connecting tubule cells: 593.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "NK-cells: 5.1;T-cells: 16.4" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary gland ductal cells, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001824 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 11: T-cells - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 51: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 9: T-cells - Adaptive immunity: Regulation" 40 Nucleoplasm Cytosol "HPA001824: " "unprognostic (9.91e-2)" "unprognostic (2.69e-1)" "unprognostic (1.01e-1)" "unprognostic (3.00e-1)" "unprognostic (5.73e-2)" "unprognostic (1.48e-1)" "unprognostic (1.98e-1)" "unprognostic (1.05e-2)" "unprognostic (4.79e-2)" "unprognostic (1.05e-1)" "potential prognostic favorable (3.11e-4)" "unprognostic (4.18e-3)" "unprognostic (2.00e-1)" "unprognostic (5.72e-3)" "unprognostic (5.30e-2)" "unprognostic (6.53e-2)" "unprognostic (3.41e-1)" "unprognostic (1.29e-1)" "unprognostic (3.74e-2)" "unprognostic (7.12e-3)" "unprognostic (2.17e-1)" "unprognostic (1.88e-2)" "unprognostic (3.49e-1)" "unprognostic (2.82e-2)" "unprognostic (2.91e-2)" "unprognostic (4.28e-1)" "unprognostic (6.55e-2)" "unprognostic (4.10e-2)" "unprognostic (1.32e-1)" "unprognostic (1.09e-2)" "unprognostic (6.20e-3)" MLLT6 "AF17, FLJ23480" ENSG00000275023 "MLLT6, PHD finger containing" P55198 17 38705273-38729795 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 52.0;Bergmann glia: 37.5;Brain excitatory neurons: 33.5;Choroid plexus epithelial cells: 65.2;Distal convoluted tubule cells: 101.8;Ependymal cells: 44.9;Loop of henle epithelial cells: 101.3;Microglia: 81.4;Oligodendrocyte progenitor cells: 45.5;Oligodendrocytes: 42.5;Papillary tip epithelial cells: 68.6;Podocytes: 67.6;Proximal tubule cells: 65.4;Renal collecting duct intercalated cells: 105.8;Renal collecting duct principal cells: 71.0;Renal connecting tubule cells: 73.9" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Stomach Adenocarcinoma (TCGA): 7.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Pancreas - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004021 Approved Approved Nucleoplasm NA NA "Cluster 64: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 102: Non-specific - Mixed function" 32 Nucleoplasm "HPA004021: " "unprognostic (6.54e-2)" "unprognostic (1.37e-1)" "unprognostic (1.93e-2)" "unprognostic (4.70e-2)" "unprognostic (5.08e-2)" "potential prognostic favorable (5.79e-4)" "unprognostic (1.82e-1)" "unprognostic (2.98e-2)" "unprognostic (4.43e-2)" "unprognostic (3.46e-2)" "unprognostic (1.48e-2)" "unprognostic (1.58e-2)" "unprognostic (9.67e-3)" "unprognostic (1.17e-2)" "unprognostic (2.60e-1)" MLN ENSG00000096395 Motilin P12872 6 33794673-33804003 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 410 "intestine: 239.2" "Cell type enriched" "Detected in some" 713 "Neuroendocrine cells: 1622.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Pancreatic Adenocarcinoma (TCGA): 1.8;Stomach Adenocarcinoma (TCGA): 1.8;Testicular Germ Cell Tumor (TCGA): 6.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "HPA069392, HPA077622" Enhanced "Secreted to blood" Hormone NA NA 450000 83000 "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 30: White matter - Myelination" "Cluster 72: Neuronal - Signal transduction" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" 2 "HPA069392: , HPA077622: " "unprognostic (4.32e-1)" "unprognostic (7.79e-1)" "unprognostic (3.72e-2)" "unprognostic (1.80e-1)" MLNR GPR38 ENSG00000102539 "Motilin receptor" O43193 13 49220338-49222377 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 1.2;thyroid gland: 1.6" "Cell type enhanced" "Detected in single" "Neutrophil progenitors: 1.8" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Testicular Germ Cell Tumor (TCGA): 2.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA070324 Approved "Plasma membrane,Cytosol" NA NA "Cluster 44: Bone marrow - Nuclear processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 37: Neutrophil progenitors - Granulopoiesis" "Plasma membrane, Cytosol" "HPA070324: " "unprognostic (3.40e-1)" MLPH "exophilin-3, l(1)-3Rk, l1Rk3, ln, Slac-2a" ENSG00000115648 Melanophilin Q9BV36 2 237485428-237555322 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 133.3;salivary gland: 118.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 337.8;Breast hormone-responsive cells: 240.6;Foveolar cells: 508.4;Goblet cells: 321.3;Lacrimal acinar cells: 267.2;Mast cells: 171.8;Melanocytes: 175.7;Mucous neck cells: 149.5;Prostatic club cells: 230.1;Prostatic glandular cells: 335.1;Salivary acinar cells: 226.3;Transitional alveolar cells: 208.0" "Cell type enriched" "Detected in some" 6 "fibroblast: 54.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA014685 Enhanced NA NA "Cluster 82: Salivary gland - Secretion" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 27: Breast cancer - Unknown function" "Cluster 68: Foveolar cells - Mucosal defense" 9 "HPA014685: " "unprognostic (1.70e-1)" "unprognostic (1.71e-2)" "unprognostic (1.59e-1)" "unprognostic (1.43e-1)" "unprognostic (2.54e-1)" "unprognostic (9.06e-2)" "potential prognostic unfavorable (5.38e-5)" "unprognostic (2.92e-3)" "unprognostic (2.24e-2)" "unprognostic (1.83e-1)" "potential prognostic unfavorable (5.60e-4)" "unprognostic (5.65e-3)" "unprognostic (5.58e-2)" "unprognostic (9.44e-2)" "unprognostic (1.10e-1)" "unprognostic (1.65e-1)" "unprognostic (1.80e-1)" "unprognostic (1.25e-2)" "unprognostic (3.08e-3)" "unprognostic (4.61e-3)" "unprognostic (2.93e-2)" "unprognostic (4.15e-2)" "unprognostic (1.84e-1)" "unprognostic (1.15e-1)" "unprognostic (1.75e-2)" "unprognostic (2.52e-3)" "unprognostic (9.47e-2)" "unprognostic (2.57e-1)" "unprognostic (9.04e-2)" "unprognostic (1.24e-2)" "unprognostic (9.36e-2)" MLST8 "GbetaL, GBL, Lst8, Pop3" ENSG00000167965 "MTOR associated protein, LST8 homolog" Q9BVC4 16 2204248-2209453 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 78.8;Late spermatids: 181.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019935, HPA041841, HPA068631" Approved Approved "Nucleoplasm,Golgi apparatus,Cell Junctions" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 24: Non-specific - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 54: Non-specific - Transcription" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 17 Nucleoplasm "Golgi apparatus, Cell Junctions" "CAB019935: , HPA041841: , HPA068631: " "unprognostic (2.20e-1)" "unprognostic (1.89e-1)" "unprognostic (3.40e-1)" "unprognostic (8.42e-2)" "unprognostic (2.76e-1)" "unprognostic (3.36e-2)" "unprognostic (8.76e-2)" "unprognostic (2.19e-2)" "unprognostic (1.03e-1)" "unprognostic (6.29e-2)" "unprognostic (1.76e-1)" "unprognostic (7.00e-3)" "unprognostic (7.75e-3)" "validated prognostic unfavorable (9.40e-4)" "validated prognostic unfavorable (3.05e-4)" "unprognostic (3.21e-2)" "unprognostic (1.27e-1)" "unprognostic (9.68e-2)" "unprognostic (2.11e-1)" "unprognostic (7.00e-2)" "unprognostic (1.32e-1)" "unprognostic (2.67e-2)" "potential prognostic unfavorable (5.43e-4)" "unprognostic (5.79e-1)" "unprognostic (3.39e-2)" "unprognostic (2.30e-2)" "unprognostic (1.24e-1)" "unprognostic (6.76e-2)" "unprognostic (2.73e-1)" "unprognostic (2.49e-1)" "unprognostic (1.50e-1)" MLX "bHLHd13, MAD7, MXD7, TCFL4" ENSG00000108788 "MAX dimerization protein MLX" Q9UH92 17 42567072-42573239 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 179.5;Enterocytes: 121.0;Esophageal apical cells: 161.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025329, HPA052766, HPA064438" Approved Supported "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 27: Breast cancer - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 12 Nucleoplasm "Nuclear membrane, Cytosol" "CAB025329: , HPA052766: , HPA064438: " "unprognostic (1.55e-1)" "potential prognostic unfavorable (5.77e-4)" "unprognostic (1.09e-1)" "unprognostic (3.09e-2)" "unprognostic (5.72e-2)" "unprognostic (1.00e-2)" "unprognostic (1.71e-1)" "unprognostic (2.22e-1)" "unprognostic (6.30e-2)" "unprognostic (5.03e-3)" "potential prognostic favorable (1.74e-7)" "unprognostic (1.55e-1)" "unprognostic (2.21e-1)" "unprognostic (3.17e-3)" "potential prognostic unfavorable (4.81e-6)" "unprognostic (4.12e-2)" "unprognostic (9.02e-2)" "unprognostic (1.65e-1)" "unprognostic (3.14e-1)" "unprognostic (5.78e-2)" "unprognostic (4.32e-2)" "unprognostic (5.19e-2)" "unprognostic (3.25e-1)" "unprognostic (2.66e-1)" "unprognostic (2.47e-2)" "unprognostic (1.09e-1)" "unprognostic (2.15e-1)" "unprognostic (3.32e-1)" "unprognostic (4.58e-1)" "unprognostic (3.65e-1)" "unprognostic (1.24e-1)" MLXIP "bHLHe36, KIAA0867, MIR, MONDOA" ENSG00000175727 "MLX interacting protein" Q9HAP2 12 122078756-122147344 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 123.0" "Cell type enhanced" "Detected in many" "Enteric stem cells: 85.8;Loop of henle epithelial cells: 85.1;Microglia: 105.6;Pancreatic acinar cells: 82.9;Platelets: 81.9;Podocytes: 119.0;Proximal tubule cells: 86.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023084 Approved NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 105: Non-specific - Mixed function" 6 "HPA023084: " "unprognostic (5.21e-3)" "unprognostic (2.55e-1)" "unprognostic (8.95e-3)" "unprognostic (3.03e-3)" "unprognostic (1.37e-1)" "unprognostic (3.81e-2)" "unprognostic (7.80e-2)" "unprognostic (3.15e-2)" "unprognostic (6.87e-2)" "unprognostic (2.58e-2)" "unprognostic (8.80e-3)" "unprognostic (2.18e-2)" "unprognostic (6.36e-2)" "potential prognostic unfavorable (3.92e-4)" "unprognostic (2.44e-1)" "unprognostic (3.41e-1)" "unprognostic (1.36e-1)" "unprognostic (1.06e-1)" "unprognostic (2.29e-1)" "unprognostic (3.18e-2)" "unprognostic (9.24e-3)" "unprognostic (1.16e-2)" "unprognostic (4.34e-2)" "unprognostic (7.67e-2)" "unprognostic (7.73e-3)" "unprognostic (3.28e-2)" "unprognostic (1.16e-1)" "unprognostic (3.81e-1)" "unprognostic (3.88e-1)" "unprognostic (1.74e-2)" "unprognostic (2.28e-1)" MLXIPL "bHLHd14, CHREBP, MIO, MONDOB, WBSCR14, WS-bHLH" ENSG00000009950 "MLX interacting protein like" Q9NP71 7 73593194-73624543 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "liver: 546.1" "Cell type enhanced" "Detected in many" "Adipocytes: 500.8;Adrenal cortex cells: 179.5;Cholangiocytes: 99.1;Enterocytes: 120.8;Epididymal principal cells: 103.7;Hepatocytes: 405.4;Microglia: 104.0;Myonuclei: 120.2;Neuroendocrine cells: 114.0;Paneth cells: 92.8;Proximal tubule cells: 193.1;Sertoli cells: 96.7" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 118.2" "Cancer enriched" "Detected in many" 5 "Liver Hepatocellular Carcinoma (TCGA): 96.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 20.2" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Lung - Alveolar cells type 2, Pituitary gland - Gonadotropes, Skin - Adipocytes (Skin)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA064640 Supported Nucleoplasm NA NA "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 37: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 89: Adipocytes - Lipid metabolism" 5 Nucleoplasm "HPA064640: " "unprognostic (1.26e-1)" "unprognostic (2.94e-2)" "unprognostic (1.16e-1)" "unprognostic (4.28e-2)" "unprognostic (1.23e-1)" "unprognostic (2.55e-1)" "unprognostic (1.82e-1)" "unprognostic (7.01e-2)" "unprognostic (2.77e-3)" "unprognostic (2.84e-2)" "unprognostic (1.08e-2)" "unprognostic (3.08e-3)" "unprognostic (1.13e-2)" "unprognostic (2.44e-2)" "unprognostic (2.05e-2)" "unprognostic (7.68e-2)" "unprognostic (2.33e-1)" "unprognostic (1.77e-3)" "unprognostic (2.01e-1)" "unprognostic (1.68e-1)" "unprognostic (3.41e-2)" "unprognostic (1.31e-1)" "unprognostic (2.39e-1)" "unprognostic (1.84e-1)" "unprognostic (4.99e-3)" MLYCD "hMCD, MCD" ENSG00000103150 "Malonyl-CoA decarboxylase" O95822 16 83899115-83951445 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 20.2" "Cell type enhanced" "Detected in many" "Astrocytes: 31.0;Bergmann glia: 30.8;Choroid plexus epithelial cells: 33.3;Cone photoreceptor cells: 29.0;Myonuclei: 29.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031625 Enhanced NA NA 18000 "Cluster 22: Eosinophils - Transcription" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 19: Astrocytes - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 55: Myocytes - Oxidative muscle function" 1 "HPA031625: " "unprognostic (2.88e-2)" "unprognostic (1.07e-1)" "unprognostic (1.30e-1)" "unprognostic (3.95e-1)" "unprognostic (1.47e-1)" "unprognostic (2.13e-1)" "unprognostic (2.98e-1)" "potential prognostic favorable (5.52e-4)" "unprognostic (3.27e-1)" "potential prognostic favorable (2.23e-7)" "unprognostic (5.62e-2)" "unprognostic (1.89e-3)" "potential prognostic favorable (3.05e-5)" "unprognostic (6.25e-3)" "unprognostic (1.49e-2)" "unprognostic (6.81e-2)" "unprognostic (2.99e-2)" "unprognostic (3.55e-2)" "unprognostic (4.83e-2)" "potential prognostic favorable (5.86e-4)" "unprognostic (2.28e-1)" "unprognostic (4.59e-1)" "unprognostic (1.32e-1)" "unprognostic (2.12e-1)" "unprognostic (2.56e-1)" "unprognostic (1.09e-1)" "unprognostic (1.91e-1)" "unprognostic (1.76e-1)" MMAA cblA ENSG00000151611 "Metabolism of cobalamin associated A" Q8IVH4 4 145599042-145660033 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Chaperone, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 22.9" "Cell type enriched" "Detected in many" 6 "Early spermatids: 299.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037361, HPA058187" Supported Supported Cytosol No No "Cluster 42: Non-specific - Vesicular transport" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 2: Neurons - Nucleosome" "Cluster 55: Lymphoma - Immune response" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 3 Cytosol "HPA037361: , HPA058187: " "unprognostic (1.35e-1)" "unprognostic (9.04e-3)" "unprognostic (7.53e-2)" "unprognostic (1.32e-1)" "potential prognostic favorable (7.70e-4)" "unprognostic (2.26e-1)" "unprognostic (2.60e-1)" "unprognostic (1.54e-2)" "unprognostic (1.26e-1)" "unprognostic (3.48e-1)" "validated prognostic favorable (1.69e-10)" "validated prognostic favorable (1.34e-5)" "unprognostic (2.85e-2)" "unprognostic (1.26e-2)" "potential prognostic favorable (3.57e-9)" "unprognostic (2.13e-1)" "unprognostic (1.02e-1)" "unprognostic (4.89e-2)" "unprognostic (1.63e-1)" "unprognostic (1.11e-1)" "unprognostic (7.04e-3)" "potential prognostic unfavorable (5.15e-4)" "unprognostic (4.23e-1)" "unprognostic (2.80e-1)" "unprognostic (2.31e-1)" "unprognostic (1.88e-1)" "unprognostic (2.51e-1)" "unprognostic (3.60e-2)" "unprognostic (3.53e-1)" "unprognostic (2.87e-2)" "unprognostic (3.43e-1)" MMAB "cblB, CFAP23" ENSG00000139428 "Metabolism of cobalamin associated B" Q96EY8 12 109553715-109573580 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 105.3" "Cell type enhanced" "Detected in many" "Breast lactating cells: 202.3;Esophageal apical cells: 162.7;Hepatocytes: 220.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039017 Supported Approved Mitochondria NA NA 43000 "Cluster 30: Non-specific - DNA binding" "Cluster 70: Non-specific - Protein processing" "Cluster 30: White matter - Myelination" "Cluster 35: RS4;11 - Unknown function" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 19 Mitochondria "HPA039017: " "unprognostic (2.27e-2)" "unprognostic (6.90e-3)" "unprognostic (4.06e-2)" "unprognostic (3.47e-3)" "unprognostic (1.81e-1)" "unprognostic (2.88e-1)" "unprognostic (8.90e-3)" "unprognostic (1.14e-1)" "unprognostic (2.42e-1)" "unprognostic (2.82e-2)" "unprognostic (3.40e-2)" "unprognostic (2.73e-1)" "unprognostic (1.96e-3)" "unprognostic (1.55e-1)" "unprognostic (3.98e-2)" "unprognostic (2.09e-1)" "unprognostic (1.06e-2)" "unprognostic (1.55e-1)" "unprognostic (6.61e-2)" "unprognostic (4.11e-1)" "unprognostic (1.78e-2)" "unprognostic (2.17e-2)" "unprognostic (8.60e-2)" "unprognostic (2.07e-1)" "unprognostic (8.57e-2)" "unprognostic (2.05e-1)" "unprognostic (4.25e-2)" "unprognostic (1.17e-1)" "unprognostic (1.93e-1)" "unprognostic (7.31e-2)" "unprognostic (3.36e-2)" MMACHC "cblC, DKFZP564I122" ENSG00000132763 "Metabolism of cobalamin associated C" Q9Y4U1 1 45500300-45513382 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Oxidoreductase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 16.2" "Cell type enhanced" "Detected in many" "Epicardial cells: 22.7;Hepatocytes: 28.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Uterine Corpus Endometrial Carcinoma (TCGA): 48.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027394, HPA027399, HPA027402" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 37: Non-specific - mRNA processing" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 11 Nucleoplasm "Plasma membrane, Cytosol" "HPA027394: , HPA027399: , HPA027402: " "unprognostic (1.14e-1)" "unprognostic (9.60e-2)" "unprognostic (2.27e-2)" "unprognostic (3.34e-3)" "unprognostic (4.40e-3)" "unprognostic (1.50e-1)" "unprognostic (5.87e-2)" "unprognostic (2.65e-2)" "unprognostic (6.15e-2)" "unprognostic (2.05e-2)" "potential prognostic favorable (1.26e-4)" "unprognostic (5.29e-3)" "unprognostic (1.03e-1)" "unprognostic (6.97e-2)" "unprognostic (9.56e-2)" "unprognostic (1.44e-1)" "unprognostic (1.60e-1)" "unprognostic (5.42e-2)" "unprognostic (3.70e-2)" "unprognostic (3.21e-1)" "unprognostic (7.61e-2)" "unprognostic (4.36e-3)" "unprognostic (1.65e-1)" "unprognostic (3.22e-1)" "unprognostic (4.94e-3)" "unprognostic (5.13e-3)" "unprognostic (1.61e-1)" "unprognostic (3.17e-2)" "unprognostic (2.65e-1)" "unprognostic (1.30e-1)" "unprognostic (1.02e-1)" MMADHC "C2orf25, cblD, CL25022" ENSG00000168288 "Metabolism of cobalamin associated D" Q9H3L0 2 149569637-149587778 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 440.2;Late primary spermatocytes: 366.4;Syncytiotrophoblasts: 288.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037531, HPA037532" Supported NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 7 "HPA037531: , HPA037532: " "unprognostic (2.30e-1)" "unprognostic (1.29e-2)" "unprognostic (3.02e-2)" "unprognostic (8.00e-2)" "unprognostic (2.05e-1)" "unprognostic (1.31e-1)" "unprognostic (1.85e-1)" "unprognostic (1.66e-1)" "unprognostic (2.78e-3)" "potential prognostic unfavorable (6.19e-4)" "potential prognostic favorable (3.62e-8)" "unprognostic (3.41e-3)" "unprognostic (1.51e-2)" "unprognostic (2.30e-2)" "unprognostic (4.46e-2)" "unprognostic (1.61e-3)" "unprognostic (1.05e-1)" "unprognostic (3.44e-1)" "unprognostic (7.33e-2)" "unprognostic (2.89e-1)" "unprognostic (3.30e-2)" "unprognostic (1.88e-3)" "unprognostic (3.29e-2)" "unprognostic (1.24e-1)" "unprognostic (2.31e-2)" "unprognostic (3.42e-1)" "unprognostic (3.79e-2)" "unprognostic (2.55e-2)" "unprognostic (2.95e-1)" "unprognostic (1.96e-1)" "unprognostic (1.19e-1)" MMD "MMA, PAQR11" ENSG00000108960 "Monocyte to macrophage differentiation associated" Q15546 17 55392622-55421924 "Predicted membrane proteins, Transporters" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 142.9;brain: 101.7" "Cell type enriched" "Detected in many" 11 "Platelets: 2538.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026978 Approved Vesicles NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 47: Platelets - Hemostasis" 19 Vesicles "HPA026978: " "unprognostic (9.40e-2)" "unprognostic (1.68e-1)" "unprognostic (1.84e-1)" "unprognostic (4.34e-2)" "unprognostic (2.13e-2)" "unprognostic (1.06e-1)" "unprognostic (8.53e-2)" "unprognostic (3.45e-3)" "unprognostic (3.89e-2)" "unprognostic (1.95e-3)" "potential prognostic favorable (6.84e-4)" "unprognostic (2.02e-2)" "potential prognostic unfavorable (1.24e-6)" "validated prognostic unfavorable (9.76e-5)" "validated prognostic unfavorable (2.47e-5)" "unprognostic (3.76e-3)" "unprognostic (3.38e-2)" "unprognostic (1.30e-1)" "unprognostic (6.05e-2)" "unprognostic (5.52e-2)" "unprognostic (1.62e-2)" "unprognostic (1.32e-1)" "potential prognostic unfavorable (7.42e-5)" "potential prognostic unfavorable (8.27e-5)" "unprognostic (5.08e-1)" "unprognostic (2.03e-3)" "unprognostic (1.40e-1)" "unprognostic (6.22e-3)" "unprognostic (3.70e-2)" "unprognostic (1.54e-2)" "unprognostic (1.89e-1)" MMD2 PAQR10 ENSG00000136297 "Monocyte to macrophage differentiation associated 2" Q8IY49 7 4905989-4959213 "Predicted membrane proteins, Transporters" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 28.0" "Cell type enhanced" "Detected in some" "Astrocytes: 308.3;Bergmann glia: 138.9;Brain inhibitory neurons: 86.0;Cone photoreceptor cells: 169.7;Lactotrophs: 155.6;Oligodendrocyte progenitor cells: 194.4;Rod photoreceptor cells: 128.2;Sertoli cells: 442.5;Somatotrophs: 125.2;Thyrotrophs: 133.2" "Cell type enhanced" "Detected in all" "astrocyte: 318.4;medium spiny neuron: 213.5" "Cancer enriched" "Detected in single" 60 "Glioblastoma Multiforme (TCGA): 6.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Enteric glia cells, Pituitary gland - Lactotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" "unprognostic (2.52e-1)" "unprognostic (2.31e-2)" MME "CALLA, CD10, NEP" ENSG00000196549 "Membrane metalloendopeptidase" P08473 3 155024124-155183704 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Charcot-Marie-Tooth disease, Disease variant, FDA approved drug targets, Neurodegeneration, Neuropathy, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 314.1;kidney: 282.6" "Cell type enhanced" "Detected in many" "Adipocytes: 329.8;Basal prostatic cells: 283.8;Breast myoepithelial cells: 274.7;Endometrial stromal cells: 456.0;Enterocytes: 898.7;Fibro-adipogenic progenitors: 274.6;Neutrophils: 1431.5;Podocytes: 2387.7;Prostatic glandular cells: 346.5;Proximal tubule cells: 929.1;Thymocytes: 293.9" "Group enriched" "Detected in many" 7 "lower rhombic lip: 200.6;medium spiny neuron: 247.5" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "basal ganglia: 37.9" "Immune cell enriched" "Detected in some" 123 "neutrophil: 139.9" "Lineage enriched" "Detected in many" 123 "granulocytes: 139.9" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipocytes (Visceral), Kidney - Podocytes, Liver - Hepatocytes, Prostate - Prostate glandular cells" "Region enhanced" "Detected in many" "basal ganglia: 28.1" "Region enhanced" "Detected in all" "basal ganglia: 43.8" "CAB000013, HPA052583, HPA056072" Enhanced Approved "Plasma membrane,Centrosome,Basal body,Cytosol" NA NA 470000 "Cluster 35: Neutrophils - Protein binding" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 24: Neutrophils - Innate immunity signal integration" 9 "Plasma membrane, Centrosome, Basal body" Cytosol "CAB000013: , HPA052583: , HPA056072: " "unprognostic (2.30e-1)" "unprognostic (2.49e-1)" "unprognostic (5.64e-2)" "unprognostic (5.09e-3)" "unprognostic (8.46e-2)" "unprognostic (2.60e-2)" "unprognostic (3.20e-2)" "unprognostic (1.01e-2)" "unprognostic (1.31e-2)" "potential prognostic favorable (3.40e-4)" "unprognostic (2.64e-2)" "unprognostic (2.59e-2)" "unprognostic (1.41e-1)" "unprognostic (2.37e-2)" "unprognostic (3.78e-1)" "unprognostic (1.31e-1)" "potential prognostic unfavorable (2.61e-4)" "unprognostic (1.59e-1)" "unprognostic (1.64e-1)" "unprognostic (9.93e-2)" "unprognostic (6.95e-3)" "unprognostic (1.39e-2)" "unprognostic (1.07e-1)" "unprognostic (6.95e-2)" "unprognostic (1.87e-1)" "unprognostic (2.21e-1)" "unprognostic (1.51e-1)" "unprognostic (1.05e-1)" "unprognostic (3.37e-3)" "unprognostic (3.65e-2)" MMEL1 "MMEL2, NEPII, NL1, NL2, SEP" ENSG00000142606 "Membrane metalloendopeptidase like 1" Q495T6 1 2590639-2633016 "Enzymes, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 23.8" "Cell type enhanced" "Detected in some" "Early spermatids: 23.0;Endometrial secretory cells: 10.7;Ependymal cells: 9.7;Foveolar cells: 3.3;Gastric chief cells: 20.7;Late primary spermatocytes: 5.4;Late spermatids: 8.4;Mucous neck cells: 4.7;Prostatic club cells: 4.1" "Group enriched" "Detected in some" 4 "ependymal cell: 11.1;mammillary body: 4.2" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 17.8;Uterine Corpus Endometrial Carcinoma (TCGA): 22.9" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "breast cancer: 1.9;prostate cancer: 1.3" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA007876, HPA008205, CAB020786" Uncertain "Intracellular and membrane" Enzyme NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 79: Testis - Spermatogenesis" "Cluster 46: Brainstem - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" "CAB020786: , HPA007876: , HPA008205: " "unprognostic (1.67e-1)" "unprognostic (7.11e-2)" "unprognostic (3.97e-3)" "unprognostic (2.03e-2)" "unprognostic (4.17e-1)" "unprognostic (2.48e-1)" "unprognostic (1.57e-1)" "unprognostic (6.84e-2)" "unprognostic (1.19e-3)" "unprognostic (2.16e-1)" "unprognostic (1.24e-1)" "unprognostic (1.45e-1)" "unprognostic (1.20e-1)" "unprognostic (1.92e-2)" "unprognostic (1.04e-1)" "unprognostic (2.89e-1)" "unprognostic (1.72e-1)" "unprognostic (5.62e-2)" "unprognostic (5.27e-2)" "unprognostic (1.18e-1)" "unprognostic (6.40e-2)" "unprognostic (2.82e-1)" MMGT1 "EMC5, TMEM32" ENSG00000169446 "Membrane magnesium transporter 1" Q8N4V1 X 135960588-135974029 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032037 Approved NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 36: Non-specific - mRNA processing" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 122 "HPA032037: " "unprognostic (4.82e-2)" "unprognostic (9.46e-3)" "unprognostic (2.25e-1)" "unprognostic (2.23e-1)" "unprognostic (1.16e-1)" "potential prognostic unfavorable (7.20e-5)" "unprognostic (2.24e-1)" "unprognostic (6.28e-2)" "unprognostic (6.24e-2)" "unprognostic (5.48e-2)" "potential prognostic favorable (3.13e-7)" "unprognostic (3.03e-2)" "unprognostic (3.29e-1)" "unprognostic (4.17e-2)" "unprognostic (2.36e-2)" "unprognostic (2.24e-1)" "unprognostic (1.70e-2)" "unprognostic (7.65e-2)" "unprognostic (9.16e-2)" "unprognostic (1.87e-2)" "unprognostic (2.47e-1)" "unprognostic (1.33e-1)" "unprognostic (1.36e-1)" "unprognostic (5.68e-2)" "unprognostic (2.14e-2)" "unprognostic (2.77e-1)" "unprognostic (4.61e-1)" "unprognostic (2.44e-1)" "unprognostic (3.41e-1)" "unprognostic (5.77e-2)" "unprognostic (1.15e-1)" MMP1 CLG ENSG00000196611 "Matrix metallopeptidase 1" P03956 11 102789401-102798160 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Collagen degradation, Host-virus interaction" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "gallbladder: 70.7;stomach 1: 44.2;urinary bladder: 48.6" "Cell type enhanced" "Detected in some" "Endometrial secretory cells: 208.7;Fibroblasts: 91.6;Gastric chief cells: 48.1;Gastric progenitor cells: 130.7;Mucous neck cells: 49.6;Ocular epithelial cells: 119.4;Pancreatic duct cells: 159.1;Parietal cells: 37.1;Platelets: 35.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 496.0" "Region enriched" "Detected in single" 7 "cerebral cortex: 3.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 912.7;thyroid cancer: 1579.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "amygdala: 1.1;hippocampal formation: 4.0" HPA004920 Approved Vesicles "Secreted to extracellular matrix" Enzyme NA NA 56000 "Cluster 11: Esophagus - Basic cellular processes" "Cluster 12: Non-specific - Vasculature" "Cluster 72: Neuronal - Signal transduction" "Cluster 17: Non-specific - RNA processing" 1 Vesicles "HPA004920: " "unprognostic (1.32e-2)" "unprognostic (1.32e-2)" "unprognostic (1.77e-1)" "potential prognostic unfavorable (8.52e-5)" "unprognostic (1.73e-1)" "unprognostic (3.17e-3)" "unprognostic (1.24e-2)" "unprognostic (2.01e-1)" "unprognostic (4.05e-2)" "potential prognostic unfavorable (2.45e-5)" "unprognostic (4.96e-3)" "unprognostic (2.81e-1)" "potential prognostic unfavorable (2.86e-5)" "potential prognostic unfavorable (3.71e-7)" "unprognostic (3.80e-3)" "unprognostic (1.07e-2)" "unprognostic (1.72e-1)" "unprognostic (9.81e-2)" "unprognostic (1.75e-1)" "unprognostic (9.73e-2)" "unprognostic (4.29e-2)" "unprognostic (2.49e-3)" "unprognostic (2.06e-1)" "unprognostic (9.25e-2)" "unprognostic (3.18e-1)" "unprognostic (1.77e-2)" "unprognostic (2.56e-2)" "unprognostic (8.43e-2)" "unprognostic (2.81e-2)" "unprognostic (4.86e-3)" MMP10 STMY2 ENSG00000166670 "Matrix metallopeptidase 10" P09238 11 102770502-102780628 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 34 "endometrium 1: 249.7" "Cell type enhanced" "Detected in some" "Conjunctival goblet cells: 142.7;Endometrial secretory cells: 628.4;Ocular epithelial cells: 411.7;Respiratory basal cells: 174.5" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 85.8;Head and Neck Squamous Cell Carcinoma (TCGA): 152.9;Lung Squamous Cell Carcinoma (TCGA): 122.0" "Region enhanced" "Detected in some" "thalamus: 3.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "head and neck cancer: 33.9;Rhabdoid: 128.8;Sarcoma: 41.0" CAB002159 Uncertain Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" Enzyme NA NA "Cluster 75: Ovary - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 26: Keratinocytes - Keratinization" 7 Cytosol "Plasma membrane" "CAB002159: " "unprognostic (2.23e-1)" "unprognostic (2.37e-2)" "unprognostic (1.10e-1)" "unprognostic (2.15e-1)" "unprognostic (3.72e-2)" "unprognostic (1.67e-1)" "unprognostic (2.90e-2)" "unprognostic (1.62e-1)" "potential prognostic unfavorable (2.67e-5)" "unprognostic (1.32e-2)" "unprognostic (8.67e-2)" "unprognostic (8.83e-2)" "unprognostic (9.12e-2)" "unprognostic (4.05e-1)" "unprognostic (5.74e-2)" "unprognostic (1.39e-2)" "unprognostic (1.55e-3)" "unprognostic (3.99e-1)" "unprognostic (6.23e-2)" "unprognostic (1.31e-2)" "unprognostic (2.52e-1)" "unprognostic (4.43e-2)" "unprognostic (3.50e-1)" MMP11 STMY3 ENSG00000099953 "Matrix metallopeptidase 11" P24347 22 23768226-23784316 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "cervix: 87.0;endometrium 1: 134.2;placenta: 37.2" "Cell type enhanced" "Detected in some" "Astrocytes: 1.2;Bergmann glia: 1.2;Ependymal cells: 1.3;Microglia: 1.3;Papillary tip epithelial cells: 1.1;Proximal tubule cells: 2.7;Renal collecting duct principal cells: 1.0" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Pancreatic Adenocarcinoma (TCGA): 539.6" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 5 "plasmacytoid DC: 4.5" "Lineage enriched" "Detected in single" 5 "dendritic cells: 4.5" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Stomach - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002593, HPA055204, HPA068864" Approved Approved "Golgi apparatus,Cytosol" "Secreted to extracellular matrix" Enzyme NA NA 1200000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 105: Non-specific - Mixed function" "Golgi apparatus" Cytosol "CAB002593: , HPA055204: , HPA068864: " "unprognostic (8.96e-2)" "unprognostic (5.02e-2)" "unprognostic (8.70e-3)" "unprognostic (9.76e-2)" "unprognostic (1.05e-1)" "unprognostic (1.52e-1)" "unprognostic (6.93e-3)" "potential prognostic unfavorable (5.00e-4)" "unprognostic (2.17e-2)" "unprognostic (3.13e-2)" "unprognostic (5.18e-2)" "unprognostic (6.89e-3)" "unprognostic (1.50e-1)" "unprognostic (4.01e-2)" "unprognostic (3.70e-2)" "unprognostic (4.08e-2)" "potential prognostic unfavorable (2.89e-5)" "unprognostic (6.37e-2)" "unprognostic (1.74e-3)" "unprognostic (1.57e-1)" "potential prognostic unfavorable (3.18e-4)" "unprognostic (5.20e-3)" "unprognostic (4.29e-1)" "unprognostic (6.52e-2)" "unprognostic (5.19e-1)" "unprognostic (1.91e-3)" "unprognostic (2.27e-1)" "unprognostic (1.47e-2)" "unprognostic (1.90e-2)" "unprognostic (1.77e-1)" "unprognostic (1.43e-2)" MMP12 HME ENSG00000262406 "Matrix metallopeptidase 12" P39900 11 102862736-102874982 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 14.8;lymphoid tissue: 38.1;urinary bladder: 15.0" "Cell type enriched" "Detected in some" 18 "Extravillous trophoblasts: 562.4" "Cell type enhanced" "Detected in single" "oligodendrocyte precursor cell: 1.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 1.7;head and neck cancer: 1.3;lymphoma: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to extracellular matrix" Enzyme NA NA "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 1 "unprognostic (3.62e-1)" "unprognostic (3.73e-2)" "unprognostic (7.70e-2)" "unprognostic (1.82e-2)" "unprognostic (1.06e-1)" "unprognostic (7.77e-2)" "unprognostic (1.60e-1)" "unprognostic (4.72e-1)" "validated prognostic unfavorable (8.68e-5)" "validated prognostic unfavorable (1.67e-4)" "validated prognostic unfavorable (6.30e-5)" "validated prognostic unfavorable (5.37e-4)" "unprognostic (5.87e-2)" "potential prognostic unfavorable (9.10e-4)" "unprognostic (9.25e-3)" "unprognostic (2.51e-2)" "unprognostic (1.65e-2)" "unprognostic (5.03e-3)" "unprognostic (1.35e-1)" "unprognostic (1.26e-1)" "unprognostic (7.17e-2)" "unprognostic (2.31e-2)" "unprognostic (5.64e-2)" "unprognostic (1.55e-1)" "unprognostic (2.32e-1)" MMP13 CLG3 ENSG00000137745 "Matrix metallopeptidase 13" P45452 11 102942995-102955732 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 12 "urinary bladder: 10.7" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 1.9;Basal prostatic cells: 3.3;Distal convoluted tubule cells: 2.0;Gonadotrophs: 2.3;Prostatic hillock cells: 1.6;Renal connecting tubule cells: 1.4;Respiratory basal cells: 4.6;Respiratory deuterosomal cells: 2.1;Respiratory secretory cells: 1.0;Salivary basal cells: 1.6;Urothelial cells: 1.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 153.7;Head and Neck Squamous Cell Carcinoma (TCGA): 114.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 46.7;thyroid cancer: 26.5" "Pituitary gland - Gonadotropes, Prostate - Urothelial cells" "Not detected" "Not detected" "Not detected" "Not detected" CAB002742 Supported "Secreted to extracellular matrix" Enzyme NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 38: Secretory epithelial cells - Exocrine secretion" "CAB002742: " "unprognostic (1.77e-1)" "unprognostic (5.41e-2)" "unprognostic (3.52e-1)" "unprognostic (2.25e-1)" "unprognostic (3.94e-1)" "unprognostic (2.49e-2)" "unprognostic (2.01e-2)" "unprognostic (3.61e-1)" "unprognostic (4.39e-3)" "unprognostic (1.11e-1)" "unprognostic (3.00e-1)" "unprognostic (4.19e-3)" "unprognostic (6.55e-2)" "unprognostic (2.48e-2)" "unprognostic (4.05e-2)" "unprognostic (6.20e-2)" "unprognostic (4.05e-3)" "potential prognostic unfavorable (1.16e-4)" "unprognostic (9.62e-2)" "unprognostic (4.79e-2)" "unprognostic (1.67e-2)" "unprognostic (3.20e-2)" "unprognostic (2.49e-1)" "unprognostic (1.36e-2)" MMP14 MT1-MMP ENSG00000157227 "Matrix metallopeptidase 14" P50281 14 22836560-22849041 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant, Osteoporosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 121.7;Decidual stromal cells: 198.3;Extravillous trophoblasts: 375.3;Fibroblasts: 127.1;Hofbauer cells: 102.2;Migrating cytotrophoblasts: 127.8;Syncytiotrophoblasts: 131.0" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 25.9;choroid plexus epithelial cell: 59.8;fibroblast: 38.1" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "choroid plexus: 126.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009918, HPA051432" Approved Approved "Intermediate filaments,Cytosol" No No 630000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 72: Neuronal - Signal transduction" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 36 Cytosol "Intermediate filaments" "CAB009918: , HPA051432: " "unprognostic (3.28e-1)" "unprognostic (2.05e-1)" "unprognostic (9.42e-2)" "unprognostic (9.64e-2)" "unprognostic (5.38e-2)" "unprognostic (4.84e-2)" "unprognostic (5.94e-2)" "unprognostic (1.91e-2)" "unprognostic (2.15e-2)" "unprognostic (5.32e-2)" "unprognostic (6.79e-2)" "unprognostic (1.89e-3)" "unprognostic (1.76e-1)" "unprognostic (2.56e-3)" "unprognostic (7.45e-2)" "unprognostic (3.87e-3)" "potential prognostic unfavorable (2.56e-5)" "unprognostic (1.75e-1)" "unprognostic (1.28e-1)" "potential prognostic unfavorable (7.12e-4)" "unprognostic (2.09e-3)" "unprognostic (1.08e-2)" "unprognostic (4.61e-2)" "unprognostic (4.33e-2)" "unprognostic (7.78e-2)" "unprognostic (1.57e-3)" "unprognostic (9.46e-2)" "unprognostic (4.49e-2)" "unprognostic (3.06e-2)" "unprognostic (1.74e-1)" "unprognostic (8.64e-2)" MMP15 "MT2-MMP, MTMMP2, SMCP-2" ENSG00000102996 "Matrix metallopeptidase 15" P51511 16 58025754-58046901 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 50.7" "Cell type enhanced" "Detected in many" "Cholangiocytes: 59.9;Colonocytes: 86.1;Cytotrophoblasts: 64.3;Enterocytes: 68.6;Extravillous trophoblasts: 87.0;Foveolar cells: 39.9;Hepatocytes: 43.3;Syncytiotrophoblasts: 53.3" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 21.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002611, HPA040390" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 49: Hindbrain - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 10 "Plasma membrane, Cytosol" Nucleoplasm "CAB002611: , HPA040390: " "unprognostic (3.36e-1)" "unprognostic (2.52e-2)" "unprognostic (3.24e-1)" "potential prognostic unfavorable (5.71e-5)" "unprognostic (1.62e-2)" "unprognostic (3.77e-2)" "unprognostic (4.30e-2)" "unprognostic (2.64e-2)" "unprognostic (1.20e-1)" "unprognostic (1.34e-1)" "potential prognostic favorable (4.08e-4)" "unprognostic (2.15e-2)" "potential prognostic favorable (1.06e-5)" "unprognostic (1.41e-2)" "unprognostic (6.19e-2)" "unprognostic (9.97e-2)" "unprognostic (2.35e-1)" "unprognostic (2.78e-2)" "unprognostic (2.51e-1)" "unprognostic (6.05e-2)" "unprognostic (3.70e-2)" "unprognostic (6.27e-2)" "unprognostic (4.68e-3)" "unprognostic (9.83e-2)" "unprognostic (1.59e-1)" "unprognostic (4.03e-2)" "unprognostic (3.37e-3)" "unprognostic (6.74e-2)" "unprognostic (1.47e-1)" "unprognostic (1.07e-1)" "unprognostic (3.45e-2)" MMP16 "C8orf57, DKFZp761D112, MT3-MMP" ENSG00000156103 "Matrix metallopeptidase 16" P51512 8 88032011-88328025 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.3" "Cell type enriched" "Detected in many" 6 "Oligodendrocyte progenitor cells: 2339.2" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 1706.7;oligodendrocyte precursor cell: 2825.3" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 8.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 11.0" "Lung - Fibroblasts_2, Minor Salivary Gland - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023693 Uncertain Approved Vesicles,Cytosol "Secreted to extracellular matrix" Enzyme NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" Cytosol Vesicles "HPA023693: " "unprognostic (1.11e-1)" "unprognostic (4.69e-2)" "unprognostic (2.53e-1)" "unprognostic (6.71e-2)" "potential prognostic favorable (4.56e-4)" "unprognostic (1.32e-1)" "unprognostic (3.94e-1)" "unprognostic (2.02e-1)" "unprognostic (2.90e-1)" MMP17 MT4-MMP ENSG00000198598 "Matrix metallopeptidase 17" Q9ULZ9 12 131828393-131851783 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 49.9" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 51.1;Brain inhibitory neurons: 51.0;Melanocytes: 86.9;Monocyte progenitors: 17.7;Oligodendrocyte progenitor cells: 52.1;Other brain neurons: 28.9;Thymocytes: 26.3" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 9 "Skin Cutaneous Melanoma (TCGA): 70.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "skin cancer: 61.3" "Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Prostate - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" Enzyme NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 35: Neurons - Synaptic function & neurogenesis" "unprognostic (1.76e-1)" "unprognostic (9.14e-2)" "unprognostic (3.73e-2)" "unprognostic (5.56e-2)" "unprognostic (3.02e-2)" "unprognostic (1.40e-1)" "unprognostic (8.48e-2)" "unprognostic (5.36e-2)" "unprognostic (1.64e-2)" "unprognostic (2.87e-1)" "unprognostic (5.01e-3)" "unprognostic (5.60e-3)" "unprognostic (4.25e-1)" "unprognostic (1.25e-2)" "unprognostic (1.20e-1)" "potential prognostic unfavorable (2.47e-4)" "unprognostic (6.63e-2)" "unprognostic (1.41e-2)" "unprognostic (1.59e-1)" "unprognostic (4.16e-2)" "unprognostic (3.81e-1)" "unprognostic (9.20e-3)" "unprognostic (2.15e-1)" "unprognostic (2.24e-1)" MMP19 "MMP18, RASI-1" ENSG00000123342 "Matrix metallopeptidase 19" Q99542 12 55835433-55842966 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted secreted proteins" "Angiogenesis, Collagen degradation, Differentiation" "Developmental protein, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 37.8" "Cell type enhanced" "Detected in many" "cDC: 117.0;Decidual stromal cells: 122.4;Extravillous trophoblasts: 84.0;Fibroblasts: 100.0;Hepatic stellate cells: 129.1;Kupffer cells: 132.2;Macrophages: 237.8;Mesothelial cells: 85.1;Migrating cytotrophoblasts: 70.8;monocytes: 271.9;Ovarian stromal cells: 130.6;Schwann cells: 63.0" "Cell type enriched" "Detected in some" 4 "fibroblast: 6.4" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in single" "thalamus: 2.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 3.9" "Colon - Neutrophils" "Region enriched" "Detected in many" 5 "olfactory bulb: 7.2" "Low region specificity" "Detected in all" HPA070804 Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" "Developmental protein" NA NA 3000000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 12: Non-specific - Vasculature" "Cluster 34: Testis cancer - Unknown function" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" "Endoplasmic reticulum, Vesicles" "HPA070804: " "unprognostic (1.02e-2)" "unprognostic (2.42e-1)" "unprognostic (2.11e-3)" "unprognostic (3.60e-3)" "unprognostic (1.33e-1)" "unprognostic (1.22e-1)" "unprognostic (3.56e-3)" "unprognostic (3.06e-2)" "unprognostic (9.78e-3)" "unprognostic (2.81e-1)" "potential prognostic unfavorable (7.93e-5)" "unprognostic (3.16e-3)" "unprognostic (7.24e-2)" "unprognostic (4.12e-3)" "unprognostic (4.26e-2)" "unprognostic (1.29e-1)" "unprognostic (2.98e-2)" "unprognostic (3.73e-2)" "unprognostic (7.68e-2)" "unprognostic (1.95e-3)" "unprognostic (2.07e-1)" "unprognostic (1.82e-1)" "unprognostic (4.14e-2)" "unprognostic (1.93e-1)" "unprognostic (3.01e-1)" "unprognostic (2.14e-3)" "unprognostic (6.96e-3)" "unprognostic (7.55e-3)" "unprognostic (3.80e-3)" "unprognostic (9.24e-3)" "unprognostic (1.37e-1)" MMP2 "CLG4, CLG4A, TBE-1" ENSG00000087245 "Matrix metallopeptidase 2" P08253 16 55389700-55506691 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "gallbladder: 994.4" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 414.1;Endometrial stromal cells: 180.8;Epididymal principal cells: 171.0;Extravillous trophoblasts: 823.8;Fibroblasts: 737.2;Hepatic stellate cells: 135.6;Leydig cells: 343.4;Ovarian stromal cells: 126.9;Peritubular myoid cells: 428.9" "Cell type enriched" "Detected in some" 7 "fibroblast: 151.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 781.9" "Adrenal gland - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblasts_2, Pituitary gland - Fibroblasts, Prostate - Fibroblasts, Skin - Fibroblasts_2, Spleen - Fibroblasts_2, Stomach - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001939, CAB002788" Approved Approved Vesicles "Secreted to extracellular matrix" Enzyme NA NA 160000000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 17 Vesicles "CAB002788: , HPA001939: " "unprognostic (2.47e-2)" "unprognostic (3.17e-1)" "unprognostic (2.05e-1)" "unprognostic (4.77e-3)" "unprognostic (1.01e-1)" "unprognostic (8.23e-2)" "unprognostic (2.59e-2)" "unprognostic (1.13e-2)" "unprognostic (9.94e-2)" "unprognostic (2.13e-1)" "unprognostic (6.80e-2)" "unprognostic (9.32e-3)" "unprognostic (8.54e-2)" "unprognostic (2.26e-1)" "unprognostic (1.42e-1)" "unprognostic (1.79e-1)" "unprognostic (1.79e-2)" "unprognostic (2.09e-2)" "unprognostic (2.06e-1)" "unprognostic (3.49e-3)" "unprognostic (1.47e-3)" "unprognostic (5.58e-3)" "unprognostic (1.25e-1)" "unprognostic (1.25e-1)" "unprognostic (3.32e-2)" "unprognostic (4.99e-3)" "unprognostic (8.62e-3)" "unprognostic (5.13e-3)" "unprognostic (1.16e-1)" "unprognostic (8.58e-3)" "unprognostic (2.84e-2)" MMP20 ENSG00000137674 "Matrix metallopeptidase 20" O60882 11 102576832-102625332 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Amelogenesis imperfecta" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Early spermatids: 94.3;Late primary spermatocytes: 77.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "lymphoma: 2.0;prostate cancer: 2.6" "Kidney - Proximal tubular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to extracellular matrix" Enzyme NA NA "Cluster 46: Lymphoma - Humoral immune response" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" MMP21 ENSG00000154485 "Matrix metallopeptidase 21" Q8N119 10 125753580-125775821 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" Heterotaxy "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 16 "epididymis: 50.9" "Cell type enhanced" "Detected in many" "Adipocytes: 18.3;Cardiomyocytes: 30.8;Epicardial cells: 29.6;Epididymal principal cells: 33.4;Fibro-adipogenic progenitors: 13.6;Late spermatids: 27.0;Myonuclei: 10.3" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Secreted to extracellular matrix" Enzyme NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 56: Non-specific - Sensory perception" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" "unprognostic (4.13e-2)" "unprognostic (1.27e-1)" MMP23B "MIFR, MIFR-1, MMP22" ENSG00000189409 "Matrix metallopeptidase 23B" O75900 1 1632163-1635263 "Enzymes, Predicted intracellular proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 26.3" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.6;Corticotrophs: 7.6;Fibroblasts: 3.8;Hepatic stellate cells: 6.5;Leydig cells: 14.5;NK-cells: 3.5;Oocytes: 4.6;Ovarian stromal cells: 9.5;Peritubular myoid cells: 14.9;Smooth muscle cells: 4.1" "Cell type enhanced" "Detected in some" "leukocyte: 2.0" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 12.4" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 5 "plasmacytoid DC: 11.4" "Lineage enriched" "Detected in many" 5 "dendritic cells: 11.4" "Cancer enhanced" "Detected in some" "Sarcoma: 2.5" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skin - Fibroblasts_1, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Region enriched" "Detected in some" 5 "cerebellum: 7.8" "Low region specificity" "Detected in some" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 15: Non-specific - Transcription" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 94: Gonadal somatic cells - Mixed function" "unprognostic (7.73e-2)" "unprognostic (4.92e-2)" "unprognostic (2.47e-1)" "unprognostic (2.46e-3)" "unprognostic (1.26e-2)" "unprognostic (2.06e-1)" "unprognostic (6.69e-2)" "unprognostic (4.05e-2)" "potential prognostic unfavorable (5.30e-6)" "unprognostic (3.80e-1)" "unprognostic (2.45e-1)" "unprognostic (1.94e-3)" "unprognostic (1.48e-1)" "unprognostic (7.69e-3)" "unprognostic (1.01e-1)" "unprognostic (2.62e-1)" "unprognostic (1.59e-1)" "unprognostic (3.97e-1)" "unprognostic (1.11e-1)" "unprognostic (1.24e-2)" "unprognostic (3.81e-3)" "potential prognostic unfavorable (4.98e-4)" "unprognostic (3.39e-1)" "unprognostic (2.35e-2)" "unprognostic (3.46e-1)" MMP24 MT5-MMP ENSG00000125966 "Matrix metallopeptidase 24" Q9Y5R2 20 35226690-35276998 "Enzymes, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 67.5" "Low cell type specificity" "Detected in many" "Cell type enhanced" "Detected in all" "upper rhombic lip: 194.8" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 39.4" "Region enriched" "Detected in all" 4 "cerebellum: 88.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 30.5;Kidney cancer: 41.0" "Adipose visceral - Mesothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Ductal cells, Prostate - Smooth muscle cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 68.1" "HPA049280, HPA078816" Approved Approved "Nucleoli,Plasma membrane" "Secreted to extracellular matrix" "Cell adhesion" Yes No "Cluster 71: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 2: Cerebellar granular cells - Neuronal signaling" "Nucleoli, Plasma membrane" "HPA049280: , HPA078816: " "unprognostic (3.73e-2)" "unprognostic (5.61e-2)" "unprognostic (9.50e-2)" "unprognostic (8.41e-2)" "unprognostic (1.66e-2)" "unprognostic (2.49e-2)" "unprognostic (2.70e-3)" "potential prognostic favorable (9.37e-9)" "unprognostic (1.71e-3)" "unprognostic (5.26e-3)" "unprognostic (1.05e-1)" "unprognostic (3.07e-2)" "unprognostic (2.23e-2)" "unprognostic (3.87e-1)" "unprognostic (1.16e-1)" "unprognostic (2.91e-1)" "unprognostic (4.79e-2)" "unprognostic (5.78e-2)" "unprognostic (6.95e-3)" "unprognostic (3.91e-1)" "unprognostic (1.90e-2)" "unprognostic (1.97e-1)" "unprognostic (1.66e-2)" "unprognostic (3.77e-2)" "unprognostic (8.96e-2)" "unprognostic (1.62e-1)" MMP24OS MMP24-AS1 ENSG00000126005 "MMP24 opposite strand" A0A0U1RRL7 20 35201745-35278131 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 110.3" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 112.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 62: Non-specific - Plasma proteins" "Cluster 7: Non-specific - Transcription" "unprognostic (4.80e-2)" "unprognostic (3.09e-1)" "unprognostic (1.34e-1)" "unprognostic (3.05e-1)" "unprognostic (2.84e-1)" "unprognostic (6.50e-3)" "unprognostic (9.84e-3)" "unprognostic (1.31e-1)" "unprognostic (3.58e-2)" "unprognostic (2.10e-2)" "unprognostic (2.08e-1)" "unprognostic (3.03e-3)" "unprognostic (2.59e-1)" "unprognostic (1.93e-3)" "unprognostic (1.04e-1)" "unprognostic (1.28e-1)" "unprognostic (1.35e-1)" "unprognostic (4.16e-1)" "unprognostic (9.40e-2)" "unprognostic (2.98e-2)" "unprognostic (1.00e-2)" "unprognostic (1.61e-1)" "unprognostic (3.50e-1)" "unprognostic (1.43e-1)" "unprognostic (1.14e-1)" "unprognostic (7.48e-3)" "unprognostic (1.53e-1)" "unprognostic (6.61e-2)" "unprognostic (3.55e-2)" MMP25 "MMP20, MMPL1, MT6-MMP" ENSG00000008516 "Matrix metallopeptidase 25" Q9NPA2 16 3046062-3060726 "Enzymes, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 31.3;lymphoid tissue: 75.1" "Cell type enriched" "Detected in many" 8 "Neutrophils: 577.0" "Cell type enhanced" "Detected in many" "leukocyte: 15.3" "Cancer enriched" "Detected in many" 4 "Testicular Germ Cell Tumor (TCGA): 11.9" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "basophil: 18.3;neutrophil: 20.3" "Lineage enriched" "Detected in single" 39 "granulocytes: 20.3" "Cancer enhanced" "Detected in some" "Leukemia: 2.6" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophils_2, Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Neutrophils, Spleen - Neutrophils_2, Stomach - Neutrophils, Thyroid gland - Neutrophils" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB025177, HPA055640" Uncertain Supported "Plasma membrane" "Secreted to blood" Enzyme NA NA 5000 "Cluster 35: Neutrophils - Protein binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 49: HMC-1 - Innate immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" "Plasma membrane" "CAB025177: , HPA055640: " "unprognostic (1.81e-1)" "unprognostic (2.81e-2)" "unprognostic (3.82e-2)" "unprognostic (8.63e-2)" "unprognostic (1.00e-1)" "unprognostic (1.21e-1)" "unprognostic (3.16e-1)" "unprognostic (6.46e-2)" "potential prognostic favorable (9.34e-5)" "unprognostic (6.11e-3)" "unprognostic (3.71e-1)" "unprognostic (3.49e-2)" "unprognostic (1.78e-1)" "unprognostic (1.06e-1)" "unprognostic (3.56e-2)" "unprognostic (3.42e-1)" "unprognostic (6.93e-2)" "unprognostic (2.42e-2)" "unprognostic (3.12e-1)" "unprognostic (6.18e-2)" "unprognostic (1.16e-1)" "unprognostic (5.07e-2)" MMP26 "endometase, MGC126590, MGC126592" ENSG00000167346 "Matrix metallopeptidase 26" Q9NRE1 11 4704784-4992431 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 20 "endometrium 1: 8.5" "Group enriched" "Detected in some" 6 "Endometrial glandular cells: 202.8;Endometrial luminal cells: 60.1;Prostatic glandular cells: 80.0" "Cell type enhanced" "Detected in some" "hippocampal CA1-3: 14.7;vascular associated smooth muscle cell: 16.8" "Cancer enriched" "Detected in some" 7 "Uterine Corpus Endometrial Carcinoma (TCGA): 19.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Prostate - Prostate glandular cells" "Secreted to extracellular matrix" Enzyme NA NA "Cluster 75: Ovary - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" "unprognostic (2.37e-1)" "unprognostic (1.53e-1)" "unprognostic (2.40e-1)" MMP27 ENSG00000137675 "Matrix metallopeptidase 27" Q9H306 11 102691487-102705769 "Enzymes, Predicted intracellular proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 4.4;salivary gland: 1.8;skin 1: 2.3" "Cell type enhanced" "Detected in some" "Fibro-adipogenic progenitors: 12.4;Fibroblasts: 5.2;Neutrophil progenitors: 8.8;Neutrophils: 2.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Fibroblasts, Colon - Fibroblasts, Stomach - Fibroblasts" "Not detected" "Not detected" "Not detected" "Not detected" HPA069097 Approved "Intracellular and membrane" Enzyme NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 60: Prostate cancer - Unknown function" "Cluster 108: Fibroblasts - ECM organization" "HPA069097: " MMP28 "EPILYSIN, MM28, MMP-25, MMP-28" ENSG00000271447 "Matrix metallopeptidase 28" Q9H239 17 35756249-35795707 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 99.8;Early spermatids: 33.0;Late primary spermatocytes: 17.5;Late spermatids: 54.7;Papillary tip epithelial cells: 78.6;Podocytes: 50.1;Renal collecting duct principal cells: 34.4;Sertoli cells: 23.0" "Group enriched" "Detected in many" 6 "astrocyte: 99.0;endothelial cell: 76.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "naive CD4 T-cell: 6.3;naive CD8 T-cell: 3.8" "Lineage enriched" "Detected in single" 7 "T-cells: 6.3" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 55.6" "Breast - Adipocytes (Breast), Skin - Keratinocyte (other), Spleen - Fibroblasts_2, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" Enzyme NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 2: Non-specific - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 28: Astrocytes - Homeostasis & neuron support" 8 "unprognostic (1.65e-1)" "unprognostic (1.16e-2)" "unprognostic (1.05e-1)" "unprognostic (2.27e-2)" "unprognostic (2.80e-1)" "unprognostic (9.74e-2)" "unprognostic (3.40e-1)" "unprognostic (6.98e-2)" "unprognostic (1.62e-1)" "unprognostic (3.07e-1)" "unprognostic (2.84e-1)" "unprognostic (1.03e-2)" "unprognostic (2.06e-1)" "unprognostic (4.27e-2)" "unprognostic (1.83e-3)" "unprognostic (3.53e-2)" "unprognostic (2.55e-1)" "potential prognostic unfavorable (1.13e-5)" "unprognostic (2.16e-1)" "unprognostic (7.32e-2)" "unprognostic (3.75e-3)" "unprognostic (1.49e-1)" "unprognostic (1.84e-1)" "unprognostic (5.25e-1)" "unprognostic (6.18e-3)" MMP3 "STMY, STMY1" ENSG00000149968 "Matrix metallopeptidase 3" P08254 11 102835801-102843609 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Collagen degradation, Immunity, Innate immunity" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 99.1;salivary gland: 285.6;skin 1: 72.2" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 10.0;Early spermatids: 22.8;Epididymal basal cells: 13.8;Extravillous trophoblasts: 21.4;Fibroblasts: 89.3;Gastric progenitor cells: 16.7;Late primary spermatocytes: 20.6;Ocular epithelial cells: 18.4;Salivary myoepithelial cells: 17.1;Smooth muscle cells: 27.1" "Cell type enhanced" "Detected in some" "oligodendrocyte precursor cell: 6.9" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 104.3" "Region enriched" "Detected in some" 5 "thalamus: 15.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 10 "Brain cancer: 71.9;Sarcoma: 120.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA007875 Uncertain Supported Vesicles "Secreted to extracellular matrix" Immunity NA NA 710000 "Cluster 11: Esophagus - Basic cellular processes" "Cluster 12: Non-specific - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 5 Vesicles "HPA007875: " "unprognostic (7.24e-2)" "unprognostic (9.66e-2)" "unprognostic (1.35e-1)" "potential prognostic unfavorable (4.29e-4)" "unprognostic (6.16e-2)" "unprognostic (3.03e-3)" "unprognostic (2.82e-1)" "unprognostic (3.18e-2)" "unprognostic (3.28e-2)" "potential prognostic unfavorable (4.31e-4)" "unprognostic (7.74e-2)" "unprognostic (1.11e-1)" "unprognostic (1.91e-1)" "potential prognostic unfavorable (1.42e-4)" "unprognostic (1.48e-1)" "unprognostic (6.83e-2)" "unprognostic (2.06e-1)" "unprognostic (4.54e-2)" "unprognostic (1.89e-1)" "unprognostic (7.67e-2)" MMP7 "MPSL1, PUMP-1" ENSG00000137673 "Matrix metallopeptidase 7" P09237 11 102520508-102530750 "Cancer-related genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 479.1;salivary gland: 252.5;urinary bladder: 197.0" "Cell type enhanced" "Detected in many" "Endometrial secretory cells: 961.3;Epididymal efferent duct absorptive cells: 686.2;Epididymal efferent duct ciliated cells: 287.9;Fallopian secretory cells: 784.2;Lacrimal acinar cells: 349.6;Pancreatic duct cells: 1484.7;Renal collecting duct principal cells: 321.8;Salivary acinar cells: 442.5;Salivary basal cells: 607.4;Submucosal glandular cells: 2335.9" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Pancreatic Adenocarcinoma (TCGA): 1152.9;Uterine Corpus Endometrial Carcinoma (TCGA): 957.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 627.7;Uterine cancer: 461.4" "Pancreas - Ductal cells, Skin - Eccrine sweat gland cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "CAB025869, HPA051358" Supported Approved Nucleoplasm,Vesicles,Cytosol "Secreted to extracellular matrix" Enzyme NA NA 43000 "Cluster 13: Lung - Secretion" "Cluster 15: Kidney cancer - Membrane components" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 10 "Nucleoplasm, Vesicles" Cytosol "CAB025869: , HPA051358: " "unprognostic (6.06e-2)" "unprognostic (1.13e-3)" "unprognostic (7.29e-2)" "unprognostic (1.51e-1)" "unprognostic (1.48e-2)" "unprognostic (1.54e-1)" "unprognostic (1.05e-2)" "unprognostic (1.95e-2)" "unprognostic (1.06e-1)" "unprognostic (1.76e-1)" "unprognostic (9.63e-3)" "unprognostic (3.09e-2)" "unprognostic (7.89e-2)" "potential prognostic unfavorable (4.61e-4)" "unprognostic (2.80e-1)" "unprognostic (2.27e-2)" "unprognostic (6.26e-2)" "unprognostic (8.61e-3)" "unprognostic (1.48e-2)" "unprognostic (7.47e-3)" "unprognostic (5.24e-3)" "unprognostic (3.67e-3)" "unprognostic (6.11e-3)" "unprognostic (8.59e-2)" "unprognostic (7.40e-2)" "unprognostic (1.03e-2)" "unprognostic (8.78e-3)" "unprognostic (5.09e-3)" "unprognostic (9.77e-3)" "unprognostic (9.02e-2)" "unprognostic (2.04e-1)" MMP8 CLG1 ENSG00000118113 "Matrix metallopeptidase 8" P22894 11 102711796-102727050 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 33 "bone marrow: 473.9" "Group enriched" "Detected in some" 195 "Neutrophil progenitors: 2301.1;Neutrophils: 609.2" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 12 "Skin Cutaneous Melanoma (TCGA): 10.1" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.7" "Lineage enhanced" "Detected in single" "monocytes: 1.7" "Cancer enriched" "Detected in some" 42 "skin cancer: 47.1" "Lung - Neutrophils_1, Pituitary gland - Neutrophils, Spleen - Neutrophils_1, Thyroid gland - Neutrophils" "Not detected" "Not detected" "Not detected" "Not detected" "HPA021221, HPA021763, HPA022935" Enhanced Approved Vesicles "Secreted to extracellular matrix" Enzyme NA NA 3000000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 15: Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 69: Skin cancer - ECM organization" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 1 Vesicles "HPA021221: , HPA021763: , HPA022935: " "unprognostic (8.89e-2)" "unprognostic (3.58e-1)" MMP9 CLG4B ENSG00000100985 "Matrix metallopeptidase 9" P14780 20 46008908-46016561 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "bone marrow: 355.6;lymphoid tissue: 102.5" "Group enriched" "Detected in some" 6 "Neutrophil progenitors: 1633.8;Neutrophils: 1533.7" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "thalamus: 10.9" "Immune cell enriched" "Detected in some" 127 "neutrophil: 272.9" "Lineage enriched" "Detected in single" 342 "granulocytes: 272.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 11.3" "Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophils_2, Pituitary gland - Neutrophils, Skeletal muscle - Neutrophils, Spleen - Neutrophils_2" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB000348, HPA001238, HPA063909, CAB068199, CAB068200, CAB068201" Enhanced Approved Cytosol "Secreted to blood" Enzyme NA NA 43300000 65000000 "Cluster 4: Neutrophils - Degranulation" "Cluster 15: Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 9 Cytosol "CAB000348: , CAB068199: , CAB068200: , CAB068201: , HPA001238: , HPA063909: " "unprognostic (2.27e-1)" "unprognostic (3.86e-2)" "unprognostic (9.31e-2)" "unprognostic (1.46e-1)" "unprognostic (1.46e-1)" "unprognostic (2.29e-1)" "unprognostic (3.35e-3)" "unprognostic (8.36e-2)" "unprognostic (1.53e-1)" "unprognostic (1.05e-1)" "potential prognostic unfavorable (2.61e-4)" "unprognostic (6.94e-3)" "unprognostic (4.84e-2)" "potential prognostic unfavorable (4.16e-4)" "unprognostic (1.46e-2)" "unprognostic (5.59e-2)" "unprognostic (3.73e-2)" "unprognostic (2.41e-1)" "unprognostic (1.15e-1)" "unprognostic (2.86e-2)" "unprognostic (3.18e-1)" "unprognostic (3.75e-2)" "unprognostic (7.39e-2)" "unprognostic (2.69e-1)" "unprognostic (1.65e-2)" "unprognostic (1.99e-1)" "unprognostic (2.05e-1)" "unprognostic (3.13e-1)" "unprognostic (1.14e-2)" "unprognostic (3.34e-2)" "unprognostic (6.12e-2)" MMRN1 "ECM, EMILIN4, GPIa*, MMRN" ENSG00000138722 "Multimerin 1" Q13201 4 89879532-89954629 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 5 "Lymphatic endothelial cells: 2482.9" "Group enriched" "Detected in some" 19 "central nervous system macrophage: 74.5;endothelial cell: 24.9;ependymal cell: 21.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 9 "NK-cell: 6.3;plasmacytoid DC: 2.2" "Group enriched" "Detected in many" 9 "dendritic cells: 2.2;NK-cells: 6.3" "Cancer enhanced" "Detected in some" "Leukemia: 17.0;Rhabdoid: 13.3" "Adipose subcutaneous - Smooth muscle cells, Liver - Vascular endothelial cells, Prostate - Endothelial cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA035769 Enhanced Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" "No annotated function" NA NA 150000000 "Cluster 14: Non-specific - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 44: Non-specific - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "Endoplasmic reticulum" "HPA035769: " "unprognostic (1.09e-1)" "unprognostic (2.12e-2)" "unprognostic (4.46e-2)" "unprognostic (5.99e-2)" "unprognostic (3.30e-1)" "unprognostic (8.08e-3)" "unprognostic (9.53e-3)" "unprognostic (4.89e-1)" "unprognostic (2.54e-2)" "unprognostic (4.06e-2)" "unprognostic (1.82e-1)" "unprognostic (1.87e-2)" "unprognostic (6.12e-2)" "potential prognostic unfavorable (7.62e-4)" "unprognostic (1.64e-1)" "unprognostic (7.67e-3)" "unprognostic (1.08e-1)" "unprognostic (1.46e-1)" "unprognostic (2.25e-1)" "unprognostic (6.63e-2)" "unprognostic (3.68e-3)" "unprognostic (1.01e-1)" "unprognostic (1.97e-2)" MMRN2 "EMILIN3, EndoGlyx-1, FLJ13465" ENSG00000173269 "Multimerin 2" Q9H8L6 10 86935540-86969481 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 22.8;Epicardial cells: 61.4;Epididymal basal cells: 78.0;Lymphatic endothelial cells: 51.6;Pericytes: 28.7;Urothelial cells: 31.3;Vascular endothelial cells: 188.0" "Cell type enriched" "Detected in many" 5 "endothelial cell: 112.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Lung - Endothelial cells, Minor Salivary Gland - Endothelial cells, Pancreas - Endothelial cells, Pituitary gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020741 Approved Vesicles "Secreted to extracellular matrix" "Developmental protein" NA NA 28000000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 2 Vesicles "HPA020741: " "unprognostic (3.62e-2)" "unprognostic (6.37e-2)" "unprognostic (4.31e-2)" "unprognostic (5.82e-2)" "unprognostic (4.71e-2)" "unprognostic (1.54e-2)" "unprognostic (5.36e-1)" "unprognostic (6.92e-2)" "unprognostic (2.20e-1)" "unprognostic (4.60e-2)" "validated prognostic favorable (8.09e-9)" "validated prognostic favorable (1.58e-4)" "unprognostic (1.79e-2)" "validated prognostic favorable (8.66e-4)" "validated prognostic favorable (5.04e-4)" "unprognostic (8.77e-2)" "unprognostic (7.26e-2)" "unprognostic (4.64e-2)" "unprognostic (2.41e-1)" "unprognostic (2.16e-3)" "unprognostic (3.39e-2)" "unprognostic (1.32e-1)" "unprognostic (4.27e-1)" "unprognostic (2.17e-1)" "unprognostic (1.94e-2)" "unprognostic (9.71e-3)" "unprognostic (1.73e-3)" "potential prognostic unfavorable (2.06e-4)" "unprognostic (3.36e-1)" "unprognostic (9.40e-2)" "unprognostic (1.00e-1)" MMS19 "CIAO4, hMMS19, MET18, MMS19L" ENSG00000155229 "MMS19 homolog, cytosolic iron-sulfur assembly component" Q96T76 10 97458324-97498794 "Essential proteins, Predicted intracellular proteins" "Chromosome partition, DNA damage, DNA repair, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 147.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051936, HPA056299" Approved Enhanced Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 79: Photoreceptor cells - Phototransduction" 64 Nucleoplasm "HPA051936: , HPA056299: " "unprognostic (7.01e-2)" "unprognostic (1.01e-1)" "unprognostic (1.74e-3)" "unprognostic (5.39e-2)" "unprognostic (2.66e-2)" "unprognostic (5.26e-2)" "unprognostic (1.54e-2)" "potential prognostic favorable (1.91e-4)" "unprognostic (1.01e-2)" "unprognostic (1.48e-1)" "unprognostic (1.37e-1)" "unprognostic (1.70e-1)" "unprognostic (9.35e-2)" "potential prognostic unfavorable (3.97e-4)" "unprognostic (6.95e-3)" "unprognostic (9.31e-2)" "unprognostic (1.06e-1)" "unprognostic (1.88e-1)" "unprognostic (2.67e-3)" "unprognostic (3.55e-3)" "unprognostic (4.15e-2)" "unprognostic (6.30e-2)" "unprognostic (5.07e-3)" "unprognostic (4.08e-2)" "unprognostic (1.76e-1)" "unprognostic (2.62e-1)" "unprognostic (9.54e-2)" "unprognostic (8.70e-2)" "unprognostic (2.90e-1)" "unprognostic (2.04e-1)" "unprognostic (5.01e-2)" MMS22L "C6orf167, dJ39B17.2" ENSG00000146263 "MMS22 like, DNA repair protein" Q6ZRQ5 6 97142161-97283217 "Essential proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 6.7;testis: 6.4" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 132.3;Erythrocyte progenitors: 181.8;Megakaryocyte progenitors: 119.6;Monocyte progenitors: 118.2;Neutrophil progenitors: 158.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA067042 Supported Nucleoplasm NA Yes "Cluster 5: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 30: White matter - Myelination" "Cluster 28: Non-specific - Nuclear processes" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 36 Nucleoplasm "HPA067042: " "unprognostic (1.40e-1)" "unprognostic (1.21e-2)" "unprognostic (1.26e-2)" "unprognostic (2.69e-1)" "unprognostic (2.95e-2)" "unprognostic (1.33e-1)" "unprognostic (5.31e-2)" "unprognostic (1.36e-1)" "unprognostic (8.90e-2)" "unprognostic (2.41e-1)" "potential prognostic unfavorable (1.77e-4)" "potential prognostic unfavorable (3.40e-4)" "unprognostic (7.22e-3)" "unprognostic (2.63e-2)" "unprognostic (7.18e-2)" "unprognostic (9.97e-3)" "unprognostic (1.44e-1)" "unprognostic (4.19e-1)" "unprognostic (7.25e-2)" "potential prognostic unfavorable (2.30e-4)" "unprognostic (3.38e-1)" "potential prognostic favorable (3.58e-5)" "unprognostic (3.18e-3)" "unprognostic (1.54e-2)" "unprognostic (6.80e-2)" "unprognostic (2.03e-1)" "unprognostic (1.56e-2)" MMUT "MCM, MUT" ENSG00000146085 "Methylmalonyl-CoA mutase" P22033 6 49430360-49463253 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Isomerase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 186.1" "Cell type enhanced" "Detected in many" "Hepatocytes: 148.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035971, HPA035972" Enhanced Approved Mitochondria,Cytosol NA NA 110000 "Cluster 33: Non-specific - ATP binding" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 28: Non-specific - Nuclear processes" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 10 Cytosol Mitochondria "HPA035971: , HPA035972: " "unprognostic (3.13e-1)" "unprognostic (7.55e-3)" "unprognostic (7.74e-2)" "unprognostic (6.85e-2)" "unprognostic (1.94e-2)" "unprognostic (7.81e-2)" "unprognostic (1.40e-1)" "unprognostic (2.43e-2)" "unprognostic (9.34e-2)" "validated prognostic favorable (1.90e-10)" "validated prognostic favorable (1.39e-4)" "potential prognostic favorable (8.48e-4)" "unprognostic (3.08e-2)" "unprognostic (2.49e-2)" "unprognostic (2.69e-1)" "unprognostic (4.00e-1)" "unprognostic (2.22e-1)" "unprognostic (6.01e-2)" "potential prognostic unfavorable (4.70e-4)" "unprognostic (6.27e-2)" "unprognostic (8.56e-2)" "unprognostic (1.53e-1)" "unprognostic (1.85e-3)" "unprognostic (9.49e-2)" "unprognostic (1.25e-1)" "unprognostic (1.54e-1)" "unprognostic (1.62e-1)" "unprognostic (1.19e-2)" "unprognostic (1.40e-1)" MN1 "MGCR, MGCR1, MGCR1-PEN" ENSG00000169184 "MN1 proto-oncogene, transcriptional regulator" Q10571 22 27748277-27801756 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Developmental protein" "Cancer-related genes, Disease variant, Intellectual disability, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 21.9;skeletal muscle: 46.5" "Cell type enhanced" "Detected in many" "Bergmann glia: 57.3;Brain inhibitory neurons: 42.7;Early spermatids: 69.6;Epicardial cells: 116.0;Fibro-adipogenic progenitors: 41.0;Late spermatids: 64.2;Myonuclei: 254.4;Pituitary stem cells: 107.6;Retinal amacrine cells: 133.4" "Cell type enhanced" "Detected in many" "medium spiny neuron: 82.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Pituitary gland - Fibroblasts, Spleen - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA003072 Approved Approved Nucleoplasm NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 33: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 4 Nucleoplasm "HPA003072: " "unprognostic (1.30e-1)" "unprognostic (4.64e-2)" "unprognostic (3.87e-1)" "unprognostic (2.15e-1)" "unprognostic (7.05e-3)" "unprognostic (2.87e-1)" "unprognostic (2.13e-1)" "potential prognostic favorable (6.96e-4)" "unprognostic (2.05e-2)" "unprognostic (1.62e-2)" "unprognostic (2.26e-2)" "unprognostic (3.65e-2)" "unprognostic (9.07e-2)" "unprognostic (1.73e-2)" "unprognostic (7.95e-2)" "unprognostic (1.72e-1)" "unprognostic (1.23e-2)" "unprognostic (2.79e-2)" "unprognostic (5.28e-2)" "unprognostic (5.88e-2)" "unprognostic (1.28e-1)" "unprognostic (2.09e-1)" "unprognostic (2.02e-2)" "unprognostic (1.83e-1)" "unprognostic (6.80e-3)" "unprognostic (2.02e-1)" MNAT1 "MAT1, RNF66" ENSG00000020426 "MNAT1 component of CDK activating kinase" P51948 14 60734742-60969965 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Myonuclei: 593.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000701, HPA001154, CAB004495" Approved Enhanced Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 47 Nucleoplasm "CAB004495: , HPA000701: , HPA001154: " "unprognostic (3.96e-2)" "unprognostic (3.22e-1)" "unprognostic (1.95e-1)" "unprognostic (9.92e-3)" "unprognostic (1.59e-1)" "unprognostic (3.06e-3)" "unprognostic (4.62e-2)" "potential prognostic favorable (1.92e-4)" "potential prognostic unfavorable (3.76e-4)" "unprognostic (1.34e-1)" "potential prognostic favorable (3.72e-4)" "unprognostic (9.98e-3)" "unprognostic (1.92e-1)" "unprognostic (1.14e-2)" "unprognostic (8.05e-2)" "unprognostic (1.63e-3)" "unprognostic (1.77e-1)" "unprognostic (5.63e-2)" "unprognostic (9.25e-2)" "unprognostic (7.67e-2)" "unprognostic (9.12e-3)" "unprognostic (3.64e-2)" "potential prognostic unfavorable (5.94e-4)" "unprognostic (8.32e-2)" "unprognostic (1.09e-1)" "unprognostic (3.46e-1)" "unprognostic (6.90e-2)" "unprognostic (9.49e-2)" "unprognostic (1.16e-1)" "unprognostic (9.12e-2)" "unprognostic (9.13e-3)" MND1 GAJ ENSG00000121211 "Meiotic nuclear divisions 1" Q9BWT6 4 153344649-153415118 "Predicted intracellular proteins" "DNA recombination, Meiosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 12.5;lymphoid tissue: 24.9;testis: 14.8" "Cell type enriched" "Detected in some" 4 "Oligodendrocytes: 45.0" "Group enriched" "Detected in many" 6 "committed oligodendrocyte precursor: 62.8;oligodendrocyte: 42.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "myeloid DC: 1.3;T-reg: 1.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA043499 Supported NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 11: White matter - Signal transduction" "Cluster 35: RS4;11 - Unknown function" "Cluster 80: Oligodendrocytes - Myelination" 25 "HPA043499: " "unprognostic (1.29e-2)" "unprognostic (2.93e-2)" "unprognostic (5.46e-2)" "unprognostic (2.55e-1)" "unprognostic (1.84e-1)" "unprognostic (2.89e-1)" "unprognostic (8.45e-2)" "unprognostic (4.03e-2)" "unprognostic (7.81e-2)" "unprognostic (1.04e-3)" "unprognostic (5.43e-3)" "potential prognostic unfavorable (2.62e-4)" "potential prognostic unfavorable (2.07e-7)" "validated prognostic unfavorable (4.86e-4)" "validated prognostic unfavorable (2.39e-4)" "potential prognostic unfavorable (1.70e-5)" "unprognostic (1.40e-3)" "unprognostic (1.85e-2)" "unprognostic (1.77e-1)" "unprognostic (1.85e-1)" "unprognostic (3.05e-2)" "unprognostic (1.09e-3)" "unprognostic (1.17e-2)" "unprognostic (3.00e-2)" "unprognostic (1.09e-1)" "unprognostic (2.08e-1)" "unprognostic (2.40e-2)" "unprognostic (4.01e-2)" "unprognostic (5.64e-2)" "unprognostic (7.08e-2)" "unprognostic (5.21e-3)" MNDA PYHIN3 ENSG00000163563 "Myeloid cell nuclear differentiation antigen" P41218 1 158831351-158849506 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 276.9;lymphoid tissue: 101.5" "Cell type enhanced" "Detected in some" "cDC: 323.6;Monocyte progenitors: 1201.1;monocytes: 851.3;Neutrophil progenitors: 2911.0;Neutrophils: 4000.3" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 159.8;pericyte: 70.3;vascular associated smooth muscle cell: 96.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "neutrophil: 6034.1" "Lineage enriched" "Detected in all" 4 "granulocytes: 6034.1" "Group enriched" "Detected in some" 20 "Leukemia: 41.4;lymphoma: 11.9" "Lung - Neutrophils_2, Minor Salivary Gland - Macrophages, Prostate - Macrophages, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "HPA034532, HPA073215" Enhanced Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Vesicles,Cytosol" NA NA 570000 "Cluster 21: Neutrophils - Unknown function" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 22 Nucleoplasm "Nucleoli, Nucleoli rim, Vesicles, Cytosol" "HPA034532: , HPA073215: " "unprognostic (7.16e-2)" "unprognostic (5.02e-2)" "unprognostic (1.21e-1)" "unprognostic (1.08e-1)" "unprognostic (2.27e-1)" "unprognostic (1.46e-1)" "unprognostic (3.75e-2)" "unprognostic (7.40e-2)" "unprognostic (1.65e-2)" "unprognostic (4.97e-1)" "unprognostic (2.87e-3)" "unprognostic (2.39e-1)" "unprognostic (1.67e-1)" "unprognostic (1.38e-2)" "unprognostic (2.86e-1)" "unprognostic (2.48e-3)" "unprognostic (4.40e-2)" "unprognostic (2.73e-1)" "unprognostic (1.17e-1)" "unprognostic (5.08e-1)" "unprognostic (2.13e-1)" "unprognostic (2.07e-1)" "unprognostic (1.28e-1)" "unprognostic (9.13e-2)" "unprognostic (7.74e-2)" "unprognostic (1.06e-1)" "unprognostic (4.94e-2)" "unprognostic (9.93e-2)" "unprognostic (4.22e-2)" "unprognostic (2.72e-2)" "unprognostic (2.11e-1)" MNS1 "FLJ11222, SPATA40" ENSG00000138587 "Meiosis specific nuclear structural 1" Q8NEH6 15 56421544-56465137 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Meiosis "Disease variant, Heterotaxy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 21.4;fallopian tube: 20.0;testis: 45.0" "Cell type enhanced" "Detected in many" "Early spermatids: 356.2;Endometrial ciliated cells: 324.5;Ependymal cells: 226.3;Epididymal efferent duct ciliated cells: 491.5;Fallopian tube ciliated cells: 477.4;Late primary spermatocytes: 964.3;Oocytes: 262.5;Respiratory ciliated cells: 396.4" "Cell type enhanced" "Detected in all" "ependymal cell: 263.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Colon - Enteric glia cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Respiratory ciliated cells, Prostate - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039975, HPA040382" Uncertain Approved "Nucleoplasm,Nuclear speckles,Primary cilium,Basal body,Cytosol,Perinuclear theca,Flagellar centriole,End piece" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 11: Neuronal - Sensory perception" "Cluster 107: Ciliated cells - Cilia assembly & function" 26 "Nucleoplasm, Nuclear speckles, Primary cilium, End piece" "Basal body, Cytosol, Perinuclear theca, Flagellar centriole" "HPA039975: , HPA040382: " "unprognostic (2.62e-1)" "unprognostic (1.44e-1)" "unprognostic (4.93e-2)" "unprognostic (1.39e-1)" "unprognostic (5.40e-2)" "unprognostic (1.29e-1)" "unprognostic (3.05e-1)" "unprognostic (1.24e-1)" "unprognostic (8.07e-2)" "potential prognostic unfavorable (2.73e-4)" "unprognostic (3.54e-2)" "potential prognostic favorable (7.12e-4)" "unprognostic (1.93e-2)" "unprognostic (8.91e-2)" "unprognostic (5.14e-2)" "unprognostic (1.08e-2)" "unprognostic (3.47e-2)" "unprognostic (9.40e-2)" "unprognostic (1.74e-1)" "unprognostic (4.82e-2)" "unprognostic (6.37e-2)" "unprognostic (3.25e-2)" "unprognostic (1.10e-2)" "unprognostic (2.22e-1)" "unprognostic (2.21e-1)" "unprognostic (5.83e-1)" "unprognostic (1.97e-1)" "unprognostic (2.01e-2)" "unprognostic (2.37e-1)" "unprognostic (4.55e-2)" "unprognostic (1.55e-1)" MNT "bHLHd3, lncRNA-HAL, MAD6, MXD6, ROX" ENSG00000070444 "MAX network transcriptional repressor" Q99583 17 2384073-2401104 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Urothelial cells: 119.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059532, HPA067578" Enhanced Nucleoplasm NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 69: Urothelial cells - Basic cellular functions" 8 Nucleoplasm "HPA059532: , HPA067578: " "unprognostic (3.68e-2)" "unprognostic (3.10e-1)" "unprognostic (8.74e-2)" "unprognostic (3.65e-2)" "unprognostic (7.65e-2)" "unprognostic (1.61e-1)" "unprognostic (1.43e-1)" "unprognostic (3.81e-1)" "unprognostic (2.66e-2)" "unprognostic (2.46e-1)" "unprognostic (1.50e-1)" "unprognostic (2.53e-1)" "unprognostic (8.14e-2)" "unprognostic (1.26e-2)" "unprognostic (1.59e-1)" "unprognostic (4.40e-2)" "unprognostic (8.02e-2)" "unprognostic (2.51e-2)" "unprognostic (8.83e-3)" "unprognostic (4.64e-2)" "unprognostic (1.39e-1)" "unprognostic (9.13e-3)" "unprognostic (2.74e-3)" "unprognostic (1.36e-1)" "unprognostic (5.93e-2)" "unprognostic (1.37e-2)" "unprognostic (1.12e-1)" "unprognostic (3.59e-2)" "unprognostic (4.18e-1)" "unprognostic (3.48e-2)" "unprognostic (2.12e-1)" MNX1 "HB9, HLXB9, HOXHB9, SCRA1" ENSG00000130675 "Motor neuron and pancreas homeobox 1" P50219 7 156994051-157010663 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 6.8;pancreas: 15.3" "Cell type enhanced" "Detected in some" "Colonocytes: 20.5;Corticotrophs: 85.8;Enteric stem cells: 26.5;Enteric transient amplifying cells: 22.4;Goblet cells: 40.2;Neuroendocrine cells: 46.1;Pancreatic duct cells: 77.1;Pancreatic islet cells: 53.8;Paneth cells: 42.5;Tuft cells: 34.6" "Cell type enhanced" "Detected in some" "cerebellar inhibitory: 1.5;upper rhombic lip: 1.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Pituitary gland - Corticotropes" "Not detected" "Not detected" "Region enriched" "Detected in single" 41 "spinal cord: 4.1" HPA071717 Approved Nucleoplasm,Nucleoli,Cytosol No NA "Cluster 8: Pancreas - Proteolysis" "Cluster 19: Astrocytes - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 2 Nucleoplasm "Nucleoli, Cytosol" "HPA071717: " "unprognostic (1.39e-1)" "unprognostic (1.24e-1)" "unprognostic (3.39e-2)" "unprognostic (1.09e-1)" "unprognostic (3.69e-2)" "unprognostic (2.89e-2)" "unprognostic (4.97e-2)" "unprognostic (4.08e-1)" "unprognostic (3.65e-3)" "unprognostic (1.01e-1)" "unprognostic (1.37e-2)" "unprognostic (7.45e-2)" "unprognostic (1.83e-2)" "unprognostic (6.81e-2)" "unprognostic (1.27e-1)" "unprognostic (1.87e-1)" "unprognostic (2.36e-1)" "unprognostic (3.88e-2)" "unprognostic (4.85e-2)" "unprognostic (2.56e-1)" MOAP1 "MAP-1, PNMA4" ENSG00000165943 "Modulator of apoptosis 1" Q96BY2 14 93182199-93184923 "Predicted intracellular proteins" "Apoptosis, Autophagy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 132.0" "Cell type enhanced" "Detected in some" "Astrocytes: 10.4;Bergmann glia: 18.5;Brain excitatory neurons: 40.0;Brain inhibitory neurons: 42.8;Microglia: 10.7;Oligodendrocyte progenitor cells: 11.0;Oligodendrocytes: 14.5;Other brain neurons: 74.0;Renal collecting duct principal cells: 8.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "HPA000939, HPA076948" Enhanced Approved "Nucleoplasm,Cell Junctions" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 98: Neurons - Neurotransmission & signaling" 13 Nucleoplasm "Cell Junctions" "HPA000939: , HPA076948: " "unprognostic (4.44e-3)" "unprognostic (1.00e-1)" "unprognostic (2.56e-1)" "unprognostic (4.58e-2)" "unprognostic (1.86e-1)" "unprognostic (2.76e-1)" "unprognostic (5.11e-1)" "unprognostic (6.59e-2)" "unprognostic (1.03e-2)" "unprognostic (1.08e-1)" "validated prognostic favorable (1.66e-8)" "validated prognostic favorable (1.46e-5)" "unprognostic (1.19e-1)" "unprognostic (4.72e-2)" "unprognostic (3.43e-2)" "unprognostic (6.05e-3)" "unprognostic (8.97e-3)" "unprognostic (2.62e-2)" "unprognostic (1.19e-3)" "unprognostic (1.66e-1)" "unprognostic (3.89e-2)" "unprognostic (8.17e-3)" "unprognostic (1.35e-2)" "unprognostic (1.04e-1)" "unprognostic (3.79e-1)" "unprognostic (1.02e-1)" "unprognostic (3.32e-1)" "unprognostic (5.28e-2)" "unprognostic (2.58e-1)" "unprognostic (1.92e-1)" "unprognostic (1.30e-1)" MOB1A "C2orf6, FLJ10788, FLJ11595, Mats1, MOB1, Mob4B, MOBK1B, MOBKL1B" ENSG00000114978 "MOB kinase activator 1A" Q9H8S9 2 74152528-74178898 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 333.0;Neutrophils: 423.0;Platelets: 782.3" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 121.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047088, HPA071690" Supported Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 47: Platelets - Hemostasis" 60 Nucleoli "Nucleoplasm, Cytosol" "HPA047088: , HPA071690: " "unprognostic (9.55e-3)" "unprognostic (3.72e-1)" "unprognostic (1.37e-1)" "unprognostic (9.53e-2)" "unprognostic (1.50e-1)" "unprognostic (2.46e-1)" "unprognostic (2.28e-1)" "unprognostic (1.07e-1)" "unprognostic (8.09e-2)" "potential prognostic favorable (1.01e-4)" "unprognostic (2.32e-1)" "unprognostic (5.43e-2)" "potential prognostic unfavorable (1.29e-4)" "unprognostic (8.02e-2)" "unprognostic (1.07e-1)" "unprognostic (7.27e-2)" "unprognostic (1.43e-1)" "unprognostic (1.22e-2)" "potential prognostic unfavorable (1.32e-4)" "unprognostic (6.26e-3)" "unprognostic (7.78e-3)" "unprognostic (1.95e-2)" "unprognostic (3.74e-1)" "unprognostic (2.79e-1)" "unprognostic (8.23e-2)" "unprognostic (1.94e-2)" "unprognostic (2.19e-1)" "unprognostic (6.73e-2)" "unprognostic (2.52e-1)" MOB1B "MOB4A, MOBKL1A" ENSG00000173542 "MOB kinase activator 1B" Q7L9L4 4 70902326-71022449 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 442.7;Ependymal cells: 307.2;Erythrocyte progenitors: 263.8;Microglia: 274.4;Platelets: 650.6;Renal collecting duct intercalated cells: 686.6;Renal collecting duct principal cells: 328.9;Renal connecting tubule cells: 283.0" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 372.1" "Cancer enriched" "Detected in all" 5 "Kidney Chromophobe (TCGA): 57.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047088, HPA071690" Supported Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 43 "Nucleoplasm, Nucleoli" Cytosol "HPA047088: , HPA071690: " "unprognostic (1.21e-2)" "unprognostic (1.71e-2)" "unprognostic (1.27e-2)" "unprognostic (9.21e-2)" "unprognostic (3.53e-1)" "unprognostic (2.66e-1)" "unprognostic (8.83e-3)" "unprognostic (1.01e-1)" "unprognostic (2.00e-1)" "potential prognostic favorable (5.09e-4)" "unprognostic (8.11e-3)" "unprognostic (2.08e-3)" "potential prognostic unfavorable (6.64e-4)" "unprognostic (3.52e-2)" "unprognostic (1.38e-1)" "unprognostic (5.23e-2)" "unprognostic (4.28e-2)" "unprognostic (1.97e-1)" "unprognostic (2.12e-2)" "unprognostic (3.93e-2)" "unprognostic (2.31e-3)" "unprognostic (1.48e-1)" "unprognostic (1.11e-2)" "unprognostic (3.14e-2)" "unprognostic (6.70e-2)" "unprognostic (1.69e-1)" "unprognostic (5.35e-1)" "unprognostic (1.80e-2)" "unprognostic (1.55e-1)" MOB2 HCCA2 ENSG00000182208 "MOB kinase activator 2" Q70IA6 11 1469457-1501247 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 264.7;Platelets: 356.8;Smooth muscle cells: 140.9;Vascular smooth muscle cells: 157.1" "Cell type enhanced" "Detected in all" "vascular associated smooth muscle cell: 104.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046313 Uncertain Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 74: Non-specific - Signal transduction" "Cluster 6: Non-specific - Immune response" "Cluster 24: Non-specific - Unknown function" "Cluster 62: Smooth muscle cells - Muscle contraction" 22 Nucleoli "Nucleoplasm, Cytosol" "HPA046313: " "unprognostic (1.30e-2)" "unprognostic (1.82e-1)" "unprognostic (1.82e-1)" "unprognostic (1.19e-1)" "unprognostic (2.17e-2)" "unprognostic (4.36e-2)" "potential prognostic unfavorable (6.71e-4)" "unprognostic (3.46e-2)" "unprognostic (1.59e-1)" "unprognostic (6.54e-3)" "validated prognostic favorable (1.61e-7)" "validated prognostic favorable (2.63e-5)" "unprognostic (1.04e-2)" "unprognostic (4.61e-3)" "unprognostic (2.33e-2)" "unprognostic (1.37e-2)" "unprognostic (1.13e-1)" "unprognostic (4.51e-2)" "unprognostic (3.25e-3)" "unprognostic (1.29e-2)" "unprognostic (2.76e-2)" "unprognostic (3.21e-2)" "unprognostic (2.00e-1)" "unprognostic (1.18e-1)" "unprognostic (2.12e-1)" "unprognostic (9.78e-2)" "unprognostic (1.33e-1)" "unprognostic (5.86e-2)" "unprognostic (1.09e-1)" "unprognostic (9.44e-2)" "unprognostic (1.57e-1)" MOB3A "MOB-LAK, MOB1C, MOBKL2A, moblak" ENSG00000172081 "MOB kinase activator 3A" Q96BX8 19 2071036-2096673 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "B-cells: 142.8;cDC: 209.4;monocytes: 212.3;Neutrophils: 495.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "lymphoma: 142.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057744 Uncertain "Intermediate filaments,Cytosol" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 29: Neutrophils - Innate immune cellular maintenance" "Intermediate filaments, Cytosol" "HPA057744: " "unprognostic (1.96e-1)" "unprognostic (1.74e-1)" "unprognostic (2.23e-2)" "unprognostic (2.26e-1)" "unprognostic (1.54e-1)" "unprognostic (8.28e-2)" "unprognostic (1.17e-2)" "unprognostic (2.04e-2)" "unprognostic (1.12e-2)" "unprognostic (2.41e-3)" "unprognostic (3.36e-1)" "unprognostic (3.57e-1)" "unprognostic (2.34e-3)" "unprognostic (9.20e-3)" "unprognostic (7.35e-3)" "unprognostic (4.30e-2)" "unprognostic (4.86e-2)" "unprognostic (7.43e-3)" "unprognostic (2.15e-2)" "unprognostic (1.50e-1)" "unprognostic (2.42e-2)" "unprognostic (1.03e-1)" "unprognostic (8.60e-2)" "unprognostic (1.29e-1)" "unprognostic (3.37e-1)" "unprognostic (3.08e-2)" "unprognostic (2.07e-1)" "unprognostic (1.39e-1)" "potential prognostic favorable (4.42e-4)" MOB3B "C9orf35, FLJ13204, MOB1D, MOBKL2B" ENSG00000120162 "MOB kinase activator 3B" Q86TA1 9 27325209-27529814 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.9" "Cell type enhanced" "Detected in many" "Bergmann glia: 323.9;Choroid plexus epithelial cells: 270.6;Müller glia: 363.1;Oligodendrocytes: 639.3" "Cell type enhanced" "Detected in all" "oligodendrocyte: 814.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 2.5;myeloid DC: 2.7;naive B-cell: 2.9" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "cervical cancer: 16.0" "Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057744 Uncertain "Intermediate filaments,Cytosol" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 2 "Intermediate filaments, Cytosol" "HPA057744: " "unprognostic (1.03e-1)" "unprognostic (9.68e-3)" "unprognostic (7.81e-2)" "unprognostic (2.63e-2)" "unprognostic (1.47e-1)" "unprognostic (1.83e-1)" "unprognostic (5.85e-2)" "unprognostic (2.82e-1)" "unprognostic (3.51e-1)" "validated prognostic favorable (3.10e-12)" "validated prognostic favorable (2.86e-4)" "unprognostic (3.83e-2)" "unprognostic (1.44e-1)" "unprognostic (1.07e-2)" "unprognostic (4.40e-3)" "unprognostic (1.01e-1)" "unprognostic (1.09e-1)" "unprognostic (1.01e-1)" "unprognostic (1.09e-1)" "unprognostic (5.15e-2)" "unprognostic (4.86e-1)" "unprognostic (1.92e-1)" "unprognostic (1.23e-3)" "unprognostic (3.89e-3)" "unprognostic (1.09e-1)" "unprognostic (1.92e-1)" "unprognostic (2.45e-1)" "potential prognostic unfavorable (7.81e-5)" "unprognostic (2.07e-1)" MOB3C "MOB1E, MOBKL2C" ENSG00000142961 "MOB kinase activator 3C" Q70IA8 1 46607719-46616811 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in some" 6 "Platelets: 7.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057744 Uncertain "Intermediate filaments,Cytosol" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 47: Platelets - Hemostasis" 25 "Intermediate filaments, Cytosol" "HPA057744: " "unprognostic (6.85e-3)" "unprognostic (1.25e-2)" "unprognostic (2.85e-2)" "unprognostic (7.80e-2)" "unprognostic (1.88e-1)" "unprognostic (1.27e-1)" "unprognostic (5.11e-2)" "unprognostic (7.19e-2)" "unprognostic (1.67e-1)" "potential prognostic favorable (2.38e-4)" "unprognostic (1.05e-2)" "unprognostic (2.54e-2)" "potential prognostic unfavorable (6.40e-4)" "unprognostic (7.02e-2)" "unprognostic (6.92e-3)" "unprognostic (2.49e-1)" "unprognostic (2.68e-1)" "unprognostic (3.33e-2)" "unprognostic (2.45e-1)" "unprognostic (1.46e-2)" "unprognostic (4.36e-1)" "unprognostic (8.97e-2)" "unprognostic (8.47e-2)" "unprognostic (2.61e-1)" "unprognostic (2.90e-1)" "unprognostic (1.77e-1)" "unprognostic (1.88e-1)" "unprognostic (2.81e-1)" "unprognostic (8.65e-2)" MOB4 "2C4D, CGI-95, DKFZP564M112, MOB3, MOBKL3, PHOCN, PREI3" ENSG00000115540 "MOB family member 4, phocein" Q9Y3A3 2 197515571-197553699 "Essential proteins, Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 169.7;Esophageal apical cells: 237.4;Syncytiotrophoblasts: 452.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB034082, HPA044125" Approved NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 44 "CAB034082: , HPA044125: " "unprognostic (9.38e-2)" "unprognostic (4.85e-3)" "unprognostic (5.56e-2)" "unprognostic (1.67e-1)" "unprognostic (5.79e-2)" "unprognostic (2.23e-1)" "unprognostic (4.23e-1)" "unprognostic (3.16e-2)" "unprognostic (6.25e-3)" "potential prognostic favorable (1.29e-5)" "unprognostic (2.44e-2)" "unprognostic (1.85e-2)" "potential prognostic unfavorable (4.78e-5)" "unprognostic (4.60e-2)" "unprognostic (1.04e-1)" "unprognostic (6.09e-2)" "unprognostic (1.48e-1)" "unprognostic (2.52e-1)" "unprognostic (1.16e-1)" "unprognostic (1.73e-3)" "unprognostic (2.85e-2)" "unprognostic (2.63e-2)" "unprognostic (5.03e-2)" "unprognostic (7.77e-2)" "unprognostic (8.39e-2)" "unprognostic (5.67e-2)" "unprognostic (1.22e-1)" "unprognostic (2.41e-1)" "unprognostic (1.24e-1)" MOBP ENSG00000168314 "Myelin associated oligodendrocyte basic protein" Q13875 3 39467198-39529479 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "brain: 873.9" "Cell type enriched" "Detected in some" 12 "Oligodendrocytes: 1900.1" "Cell type enriched" "Detected in all" 4 "oligodendrocyte: 2942.1" "Cancer enriched" "Detected in single" 30 "Glioblastoma Multiforme (TCGA): 17.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "cervical cancer: 2.2" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "white matter: 10285.7" HPA035152 Enhanced Supported "Cytoplasmic bodies" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 66: Non-specific - Mitochondria" "Cluster 80: Oligodendrocytes - Myelination" 5 "Cytoplasmic bodies" "HPA035152: " "unprognostic (8.46e-2)" "unprognostic (2.02e-1)" MOCOS "FLJ20733, HMCS, MOS" ENSG00000075643 "Molybdenum cofactor sulfurase" Q96EN8 18 36187497-36272157 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Molybdenum cofactor biosynthesis" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 9.7;liver: 14.9" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 166.2;Endometrial glandular cells: 57.9;Enterocytes: 79.4;Gonadotrophs: 57.5;Hepatocytes: 94.0;Papillary tip epithelial cells: 53.1;Renal connecting tubule cells: 65.9;Salivary duct cells: 50.4" "Cell type enhanced" "Detected in many" "lower rhombic lip: 23.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Pituitary gland - Somatotropes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039412, HPA047958" Uncertain Supported Mitochondria,Cytosol NA NA "Cluster 76: Non-specific - Metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 18: Adrenal cortex cells - Steroidogensis" 8 Mitochondria Cytosol "HPA039412: , HPA047958: " "unprognostic (1.43e-1)" "unprognostic (1.12e-1)" "unprognostic (1.35e-1)" "unprognostic (7.39e-2)" "potential prognostic favorable (9.44e-4)" "unprognostic (7.04e-2)" "potential prognostic unfavorable (4.08e-4)" "unprognostic (1.52e-1)" "unprognostic (1.01e-2)" "validated prognostic unfavorable (2.22e-10)" "validated prognostic unfavorable (2.20e-4)" "unprognostic (1.07e-1)" "unprognostic (1.99e-1)" "unprognostic (2.27e-2)" "unprognostic (1.14e-2)" "unprognostic (1.85e-2)" "unprognostic (2.28e-3)" "unprognostic (1.40e-2)" "unprognostic (3.20e-1)" "unprognostic (1.87e-1)" "potential prognostic unfavorable (9.34e-5)" "unprognostic (5.02e-1)" "unprognostic (3.91e-2)" "unprognostic (1.96e-2)" "unprognostic (1.03e-1)" "unprognostic (9.60e-2)" "unprognostic (1.59e-2)" "unprognostic (1.94e-1)" MOCS1 MOCOD ENSG00000124615 "Molybdenum cofactor synthesis 1" Q9NZB8 6 39899578-39934551 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Molybdenum cofactor biosynthesis" Lyase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 91.9;Cardiomyocytes: 28.4;Cytotrophoblasts: 46.2;Epicardial cells: 43.2;Hepatocytes: 48.9;Pericytes: 92.9;Vascular smooth muscle cells: 37.8" "Cell type enhanced" "Detected in all" "pericyte: 49.1;vascular associated smooth muscle cell: 39.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipocytes (Visceral), Liver - Hepatocytes, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045783, HPA058177, HPA075505" Uncertain Enhanced Cytosol NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 19: Astrocytes - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" Cytosol "HPA045783: , HPA058177: , HPA075505: " "unprognostic (1.87e-1)" "unprognostic (1.50e-1)" "unprognostic (1.97e-1)" "potential prognostic unfavorable (3.97e-5)" "unprognostic (2.09e-1)" "unprognostic (9.61e-2)" "unprognostic (1.29e-1)" "unprognostic (9.96e-2)" "unprognostic (1.11e-1)" "unprognostic (2.09e-1)" "unprognostic (1.45e-3)" "unprognostic (6.56e-3)" "unprognostic (2.29e-2)" "unprognostic (6.97e-2)" "unprognostic (5.72e-2)" "potential prognostic favorable (7.29e-4)" "unprognostic (1.19e-1)" "unprognostic (2.17e-2)" "unprognostic (5.27e-2)" "unprognostic (4.70e-2)" "unprognostic (2.49e-1)" "unprognostic (2.58e-3)" "unprognostic (9.66e-2)" "unprognostic (2.58e-2)" "unprognostic (3.48e-1)" "unprognostic (9.05e-2)" "unprognostic (1.41e-1)" "unprognostic (2.57e-3)" "unprognostic (2.11e-1)" "unprognostic (6.25e-2)" "unprognostic (6.27e-2)" MOCS2 "MOCO1, MOCS2A, MOCS2B" ENSG00000164172 "Molybdenum cofactor synthesis 2" "O96007, O96033" 5 53095679-53110063 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Molybdenum cofactor biosynthesis" Transferase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 143.0;Oocytes: 262.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037679, HPA037680" Approved Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 97: Non-specific - Cellular respiration" 2 Cytosol "Nucleoplasm, Nuclear speckles" "HPA037679: , HPA037680: " "potential prognostic favorable (3.82e-4)" "unprognostic (1.80e-1)" "unprognostic (2.14e-1)" "unprognostic (3.36e-2)" "unprognostic (2.34e-1)" "unprognostic (2.45e-1)" "unprognostic (2.19e-1)" "unprognostic (3.15e-2)" "unprognostic (1.50e-2)" "unprognostic (1.39e-2)" "potential prognostic favorable (8.16e-14)" "unprognostic (1.68e-2)" "unprognostic (3.87e-2)" "unprognostic (2.45e-2)" "unprognostic (6.71e-2)" "unprognostic (3.20e-2)" "unprognostic (2.36e-1)" "unprognostic (1.17e-1)" "unprognostic (2.81e-1)" "unprognostic (6.11e-2)" "unprognostic (9.16e-2)" "unprognostic (5.05e-2)" "unprognostic (8.58e-2)" "unprognostic (1.27e-1)" "unprognostic (1.02e-1)" "unprognostic (3.44e-2)" "unprognostic (1.55e-2)" "unprognostic (7.03e-2)" "unprognostic (1.64e-1)" "unprognostic (1.62e-1)" "unprognostic (2.04e-1)" MOCS3 "dJ914P20.3, UBA4" ENSG00000124217 "Molybdenum cofactor synthesis 3" O95396 20 50958818-50963929 "Enzymes, Essential proteins, Predicted intracellular proteins" "Molybdenum cofactor biosynthesis, tRNA processing" "Multifunctional enzyme, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 121.6;Late primary spermatocytes: 25.6;Late spermatids: 32.2;Tuft cells: 23.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027556 Uncertain NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 47: Testis - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 13 "HPA027556: " "unprognostic (1.43e-1)" "unprognostic (5.36e-2)" "unprognostic (2.22e-1)" "unprognostic (3.06e-1)" "unprognostic (3.28e-1)" "unprognostic (2.81e-1)" "unprognostic (2.92e-1)" "unprognostic (2.22e-1)" "unprognostic (9.06e-2)" "unprognostic (4.13e-3)" "potential prognostic favorable (1.82e-4)" "unprognostic (9.16e-2)" "unprognostic (1.75e-1)" "potential prognostic unfavorable (2.49e-5)" "unprognostic (7.32e-2)" "unprognostic (5.71e-2)" "unprognostic (7.94e-3)" "unprognostic (1.04e-1)" "unprognostic (1.20e-2)" "unprognostic (3.08e-1)" "unprognostic (7.24e-2)" "unprognostic (3.14e-2)" "unprognostic (4.39e-1)" "unprognostic (1.04e-2)" "potential prognostic favorable (6.93e-5)" "unprognostic (1.63e-2)" "unprognostic (1.93e-1)" "unprognostic (1.33e-1)" "unprognostic (1.28e-1)" "unprognostic (7.46e-2)" "unprognostic (1.98e-1)" MOG "BTN6, BTNL11" ENSG00000204655 "Myelin oligodendrocyte glycoprotein" Q16653 6 29657002-29672372 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 256 "brain: 686.8" "Cell type enriched" "Detected in some" 48 "Oligodendrocytes: 661.1" "Group enriched" "Detected in many" 29 "committed oligodendrocyte precursor: 307.3;oligodendrocyte: 841.5" "Group enriched" "Detected in some" 14 "Glioblastoma Multiforme (TCGA): 4.4;Kidney Chromophobe (TCGA): 1.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes" "Region enhanced" "Detected in all" "white matter: 1396.9" "Low region specificity" "Detected in all" HPA021873 Enhanced NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 69: Skin cancer - ECM organization" "Cluster 80: Oligodendrocytes - Myelination" "HPA021873: " "unprognostic (5.50e-2)" "unprognostic (2.24e-1)" "unprognostic (3.18e-1)" MOGAT1 "DGAT2L, DGAT2L1, MGAT1" ENSG00000124003 "Monoacylglycerol O-acyltransferase 1" Q96PD6 2 222671658-222709930 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycerol metabolism, Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "gallbladder: 15.8" "Group enriched" "Detected in many" 4 "Adipocytes: 145.8;Breast lactating cells: 241.3" "Cell type enhanced" "Detected in many" "astrocyte: 15.1;ependymal cell: 12.9" "Cancer enhanced" "Detected in single" "Pancreatic Adenocarcinoma (TCGA): 1.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Skin - Sebaceous gland cells, Stomach - Chief cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA049944, HPA076308" Uncertain Approved "Endoplasmic reticulum,Cytosol" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 4: Breast lactating luminal cells - Lactation" Cytosol "Endoplasmic reticulum" "HPA049944: , HPA076308: " "unprognostic (5.80e-3)" "unprognostic (3.18e-1)" "unprognostic (4.66e-1)" MOGAT2 "DGAT2L5, FLJ22644, MGAT2" ENSG00000166391 "Monoacylglycerol O-acyltransferase 2" Q3SYC2 11 75717838-75732958 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycerol metabolism, Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 19 "intestine: 45.4;liver: 23.6" "Cell type enhanced" "Detected in some" "Colonocytes: 70.5;Enteric stem cells: 21.4;Enteric transient amplifying cells: 42.4;Enterocytes: 209.8;Goblet cells: 46.1;Hepatocytes: 100.4;Paneth cells: 23.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Colon Adenocarcinoma (TCGA): 3.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "colorectal cancer: 1.0" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary gland ductal cells, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA028834 Uncertain NA NA "Cluster 77: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 1: Enterocytes - Absorption and Digestion" "HPA028834: " "unprognostic (1.03e-1)" "unprognostic (4.67e-2)" "unprognostic (2.99e-2)" "unprognostic (3.78e-2)" "validated prognostic favorable (2.69e-4)" "validated prognostic favorable (3.30e-7)" "unprognostic (1.36e-3)" "unprognostic (1.22e-1)" "unprognostic (1.54e-2)" "unprognostic (4.01e-3)" "unprognostic (1.76e-3)" MOGAT3 "DC7, DGAT2L2, MGAT3" ENSG00000106384 "Monoacylglycerol O-acyltransferase 3" Q86VF5 7 101195007-101201038 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycerol metabolism, Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "intestine: 22.9;liver: 17.2" "Cell type enhanced" "Detected in some" "Colonocytes: 97.9;Enteric stem cells: 13.6;Enteric transient amplifying cells: 37.3;Enterocytes: 160.3;Goblet cells: 18.0;Paneth cells: 38.7;Tuft cells: 11.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 15.4;Liver Hepatocellular Carcinoma (TCGA): 14.7;Rectum Adenocarcinoma (TCGA): 17.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 5.6;liver cancer: 3.7" "Colon - Colon enterocytes" HPA011940 Approved NA NA "Cluster 77: Intestine - Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" "HPA011940: " "unprognostic (3.48e-2)" "unprognostic (1.83e-1)" "unprognostic (6.10e-2)" "unprognostic (2.69e-2)" "unprognostic (1.67e-3)" "unprognostic (1.57e-1)" "unprognostic (8.22e-3)" "unprognostic (1.34e-1)" "unprognostic (1.95e-3)" "potential prognostic unfavorable (4.59e-4)" "unprognostic (5.53e-2)" "unprognostic (1.89e-1)" "unprognostic (3.10e-1)" "unprognostic (8.61e-2)" "unprognostic (3.35e-1)" MOGS "CWH41, DER7, GCS1" ENSG00000115275 "Mannosyl-oligosaccharide glucosidase" Q13724 2 74461057-74465410 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Late spermatids: 378.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011322, HPA011969" Approved Supported "Endoplasmic reticulum" NA NA 1100000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 60: Stomach - Digestion" "Cluster 27: Non-specific - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 8: Non-specific - Secretory pathway" 9 "Endoplasmic reticulum" "HPA011322: , HPA011969: " "unprognostic (1.27e-1)" "unprognostic (1.29e-1)" "unprognostic (7.19e-3)" "unprognostic (2.01e-2)" "unprognostic (1.67e-1)" "unprognostic (1.89e-2)" "unprognostic (1.92e-1)" "unprognostic (7.75e-2)" "unprognostic (1.40e-1)" "unprognostic (7.31e-2)" "unprognostic (1.59e-2)" "unprognostic (3.08e-2)" "unprognostic (5.09e-3)" "potential prognostic unfavorable (1.34e-7)" "unprognostic (5.49e-3)" "unprognostic (3.50e-1)" "unprognostic (2.59e-2)" "unprognostic (2.13e-2)" "potential prognostic favorable (8.50e-4)" "unprognostic (1.31e-1)" "unprognostic (4.12e-1)" "unprognostic (1.42e-1)" "unprognostic (1.87e-2)" "unprognostic (2.73e-1)" "unprognostic (1.31e-1)" "unprognostic (5.83e-2)" "unprognostic (1.88e-1)" "unprognostic (1.31e-1)" "unprognostic (4.19e-1)" "unprognostic (3.25e-1)" "unprognostic (2.56e-1)" MOK "RAGE, RAGE1, STK30" ENSG00000080823 "MOK protein kinase" Q9UQ07 14 102224500-102305190 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 116.9;testis: 52.1" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 432.5;Cone photoreceptor cells: 271.2;Endometrial ciliated cells: 432.3;Ependymal cells: 549.8;Epididymal efferent duct ciliated cells: 255.2;Fallopian tube ciliated cells: 284.0;Late primary spermatocytes: 291.0;Respiratory ciliated cells: 526.9;Rod photoreceptor cells: 614.8" "Cell type enhanced" "Detected in all" "ependymal cell: 555.1" "Cancer enriched" "Detected in all" 4 "Skin Cutaneous Melanoma (TCGA): 75.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 8.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Colon - Enteric glia cells, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027292 Approved "Endoplasmic reticulum,Mid piece,Principal piece,End piece" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 17: Choroid plexus - Cilium" "Cluster 72: Neuronal - Signal transduction" "Cluster 79: Photoreceptor cells - Phototransduction" "Endoplasmic reticulum" "Mid piece, Principal piece, End piece" "HPA027292: " "unprognostic (2.49e-1)" "unprognostic (2.44e-1)" "unprognostic (1.63e-1)" "unprognostic (2.86e-2)" "unprognostic (2.36e-1)" "unprognostic (7.90e-2)" "unprognostic (1.68e-1)" "unprognostic (3.10e-1)" "unprognostic (7.17e-2)" "unprognostic (2.87e-3)" "unprognostic (1.50e-1)" "unprognostic (2.42e-2)" "unprognostic (3.06e-2)" "unprognostic (1.59e-1)" "unprognostic (2.19e-1)" "unprognostic (2.20e-3)" "unprognostic (3.56e-2)" "unprognostic (1.25e-2)" "potential prognostic favorable (9.83e-4)" "unprognostic (1.11e-1)" "unprognostic (1.19e-1)" "unprognostic (2.48e-2)" "unprognostic (2.83e-1)" "unprognostic (2.10e-2)" "unprognostic (5.15e-2)" "unprognostic (1.12e-1)" "unprognostic (2.07e-1)" "unprognostic (1.22e-2)" "unprognostic (6.75e-2)" MON1A "MGC13272, SAND1" ENSG00000164077 "MON1 homolog A, secretory trafficking associated" Q86VX9 3 49907160-49930173 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Late spermatids: 60.3;Oocytes: 184.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053752, HPA058032" Uncertain Approved Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 24: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 41: Oocytes - Oogenesis" 3 Cytosol "HPA053752: , HPA058032: " "unprognostic (1.61e-1)" "unprognostic (1.87e-1)" "unprognostic (1.37e-2)" "unprognostic (2.06e-1)" "unprognostic (3.24e-1)" "unprognostic (2.37e-1)" "unprognostic (1.40e-1)" "unprognostic (1.19e-1)" "unprognostic (1.83e-1)" "unprognostic (5.84e-2)" "unprognostic (1.02e-1)" "unprognostic (1.87e-2)" "unprognostic (5.80e-2)" "unprognostic (3.57e-2)" "unprognostic (4.18e-2)" "unprognostic (3.21e-2)" "unprognostic (9.68e-2)" "unprognostic (1.26e-1)" "unprognostic (1.61e-1)" "unprognostic (1.97e-1)" "unprognostic (6.11e-2)" "unprognostic (1.44e-2)" "unprognostic (6.98e-3)" "unprognostic (2.07e-1)" "unprognostic (1.52e-1)" "unprognostic (1.76e-1)" "unprognostic (2.24e-1)" "unprognostic (1.78e-1)" "unprognostic (1.66e-2)" "unprognostic (3.72e-2)" "unprognostic (1.56e-1)" MON1B "HSRG1, KIAA0872, SAND2" ENSG00000103111 "MON1 homolog B, secretory trafficking associated" Q7L1V2 16 77190835-77202398 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 29.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Skin - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046285 Approved Approved Cytosol NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 77: Intestine - Digestion" "Cluster 19: Astrocytes - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 4 Cytosol "HPA046285: " "unprognostic (4.25e-1)" "unprognostic (7.55e-2)" "unprognostic (4.33e-3)" "unprognostic (3.94e-2)" "unprognostic (1.10e-1)" "unprognostic (1.49e-1)" "unprognostic (2.50e-1)" "unprognostic (4.28e-2)" "unprognostic (1.95e-1)" "unprognostic (1.69e-1)" "potential prognostic favorable (1.74e-5)" "unprognostic (1.65e-1)" "unprognostic (1.09e-2)" "unprognostic (7.68e-2)" "unprognostic (6.97e-2)" "unprognostic (8.93e-2)" "unprognostic (1.23e-1)" "unprognostic (1.05e-3)" "unprognostic (1.85e-2)" "unprognostic (1.30e-1)" "unprognostic (2.13e-2)" "unprognostic (1.38e-2)" "unprognostic (1.99e-2)" "unprognostic (8.68e-2)" "unprognostic (2.96e-2)" "unprognostic (5.14e-2)" "unprognostic (6.73e-2)" "unprognostic (2.57e-1)" "unprognostic (2.17e-1)" "unprognostic (2.69e-2)" "unprognostic (3.38e-2)" MON2 KIAA1040 ENSG00000061987 "MON2 homolog, regulator of endosome-to-Golgi trafficking" Q7Z3U7 12 62466817-62600476 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038697, HPA057607" Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 8 "Nucleoplasm, Nucleoli fibrillar center" "HPA038697: , HPA057607: " "unprognostic (6.66e-2)" "unprognostic (1.19e-1)" "unprognostic (1.03e-1)" "unprognostic (1.51e-1)" "unprognostic (1.55e-1)" "unprognostic (2.51e-1)" "unprognostic (8.95e-2)" "unprognostic (1.64e-1)" "unprognostic (3.38e-2)" "unprognostic (1.65e-3)" "potential prognostic favorable (1.23e-4)" "unprognostic (3.23e-3)" "unprognostic (4.93e-2)" "unprognostic (1.09e-1)" "unprognostic (5.41e-2)" "unprognostic (1.43e-1)" "unprognostic (5.36e-2)" "unprognostic (7.62e-2)" "unprognostic (8.51e-2)" "unprognostic (1.99e-2)" "unprognostic (3.51e-1)" "unprognostic (1.46e-1)" "unprognostic (1.71e-2)" "unprognostic (8.62e-2)" "unprognostic (1.61e-2)" "unprognostic (8.97e-2)" "unprognostic (4.98e-2)" "unprognostic (3.03e-1)" "unprognostic (9.15e-2)" "unprognostic (2.00e-2)" "unprognostic (8.06e-2)" MORC1 "CT33, MORC, ZCW6" ENSG00000114487 "MORC family CW-type zinc finger 1" Q86VD1 3 108958248-109118134 "Predicted intracellular proteins" "Differentiation, RNA-mediated gene silencing, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 44 "testis: 14.9" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 76.8;Early primary spermatocytes: 95.1;Early spermatids: 122.0;Epididymal clear cells: 40.8;Hematopoietic stem cells: 247.5;Innate lymphoid cells: 200.7;Late primary spermatocytes: 62.7;Late spermatids: 52.2;Microglia: 59.6;Platelets: 39.5;Thymocytes: 127.9;Thyrotrophs: 85.4;Undifferentiated spermatogonia: 66.9" "Group enriched" "Detected in some" 43 "central nervous system macrophage: 72.4;hippocampal CA4: 93.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Myeloma: 2.9" "Testis - Spermatocytes, Testis - Spermatogonia" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebellum: 3.8" HPA036413 Enhanced NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 29: Forebrain - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 2 "HPA036413: " MORC2 "AC004542.C22.1, KIAA0852, ZCW3, ZCWCC1" ENSG00000133422 "MORC family CW-type zinc finger 2" Q9Y6X9 22 30925130-30968774 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Hydrolase "Charcot-Marie-Tooth disease, Disease variant, Dwarfism, Intellectual disability, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Lineage enriched" "Detected in all" 5 "T-cells: 16.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000436, HPA077137" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 39: Testis - Nuclear processes" "Cluster 25: Non-specific - Transcription" "Cluster 66: Non-specific - Mitochondria" "Cluster 7: Non-specific - Transcription" 15 Nucleoplasm Cytosol "HPA000436: , HPA077137: " "unprognostic (1.95e-2)" "unprognostic (2.02e-2)" "unprognostic (1.67e-1)" "unprognostic (4.05e-3)" "unprognostic (1.92e-1)" "unprognostic (6.88e-2)" "unprognostic (1.24e-1)" "unprognostic (1.69e-3)" "unprognostic (4.10e-2)" "unprognostic (2.05e-2)" "unprognostic (6.84e-2)" "unprognostic (1.94e-1)" "unprognostic (7.81e-2)" "potential prognostic unfavorable (2.84e-4)" "unprognostic (8.84e-2)" "unprognostic (6.83e-2)" "unprognostic (3.72e-1)" "unprognostic (8.83e-3)" "unprognostic (1.00e-3)" "unprognostic (3.91e-1)" "unprognostic (1.06e-1)" "unprognostic (1.92e-3)" "unprognostic (3.41e-3)" "unprognostic (2.34e-1)" "unprognostic (3.64e-2)" "unprognostic (2.01e-2)" "potential prognostic unfavorable (3.61e-4)" "unprognostic (3.97e-1)" "unprognostic (2.00e-1)" "unprognostic (9.22e-3)" "unprognostic (3.15e-2)" MORC3 "KIAA0136, NXP2, ZCW5, ZCWCC3" ENSG00000159256 "MORC family CW-type zinc finger 3" Q14149 21 36320189-36386148 "Predicted intracellular proteins" "Host-virus interaction, Immunity, Innate immunity" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018406, HPA034848" Approved Enhanced Nucleoplasm,Mitochondria NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 47: Leukemia - Hemostasis" "Cluster 69: Urothelial cells - Basic cellular functions" 16 Nucleoplasm Mitochondria "HPA018406: , HPA034848: " "unprognostic (1.63e-2)" "unprognostic (6.74e-3)" "unprognostic (2.70e-2)" "unprognostic (4.25e-3)" "unprognostic (1.63e-1)" "unprognostic (1.52e-1)" "unprognostic (1.63e-2)" "unprognostic (2.54e-2)" "unprognostic (6.75e-2)" "unprognostic (1.26e-1)" "potential prognostic favorable (3.37e-6)" "unprognostic (4.80e-3)" "unprognostic (1.33e-1)" "unprognostic (1.71e-1)" "unprognostic (4.00e-2)" "unprognostic (2.48e-1)" "unprognostic (1.26e-3)" "unprognostic (1.64e-1)" "unprognostic (1.22e-1)" "unprognostic (1.12e-2)" "unprognostic (3.81e-2)" "unprognostic (3.18e-2)" "unprognostic (4.50e-2)" "unprognostic (9.71e-2)" "unprognostic (1.29e-3)" "unprognostic (1.73e-1)" "unprognostic (1.39e-1)" "unprognostic (1.58e-2)" "unprognostic (2.56e-1)" "unprognostic (2.86e-2)" "unprognostic (8.69e-2)" MORC4 "FLJ11565, ZCW4, ZCWCC2" ENSG00000133131 "MORC family CW-type zinc finger 4" Q8TE76 X 106813871-107000212 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 74.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 500.6;Migrating cytotrophoblasts: 248.0;Pancreatic duct cells: 133.1;Syncytiotrophoblasts: 325.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000395, HPA015547, HPA050250" Enhanced Enhanced Nucleoplasm NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 9: Non-specific - Receptor signaling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 6 Nucleoplasm "HPA000395: , HPA015547: , HPA050250: " "unprognostic (3.49e-1)" "potential prognostic unfavorable (2.09e-4)" "unprognostic (7.89e-2)" "unprognostic (1.27e-2)" "unprognostic (1.49e-3)" "unprognostic (3.78e-1)" "unprognostic (3.70e-1)" "unprognostic (2.94e-1)" "unprognostic (2.04e-1)" "potential prognostic unfavorable (9.83e-4)" "unprognostic (3.41e-2)" "unprognostic (7.88e-2)" "unprognostic (2.00e-2)" "unprognostic (2.43e-1)" "unprognostic (3.43e-1)" "unprognostic (2.80e-1)" "unprognostic (3.49e-2)" "unprognostic (7.06e-2)" "unprognostic (2.98e-2)" "unprognostic (6.94e-2)" "unprognostic (2.05e-2)" "unprognostic (1.91e-1)" "unprognostic (1.03e-1)" "unprognostic (1.36e-1)" "unprognostic (5.43e-3)" "unprognostic (6.34e-3)" "unprognostic (1.19e-1)" "unprognostic (2.15e-1)" "unprognostic (4.53e-2)" "unprognostic (4.39e-1)" "unprognostic (1.89e-1)" MORF4L1 "Eaf3, HsT17725, MEAF3, MORFRG15, MRG15" ENSG00000185787 "Mortality factor 4 like 1" Q9UBU8 15 78810487-78898139 "Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Growth regulation, Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 1110.3;Late primary spermatocytes: 2195.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Testis - Early spermatids, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "HPA042360, HPA062010" Approved Supported "Nuclear speckles" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 82 "Nuclear speckles" "HPA042360: , HPA062010: " "unprognostic (4.15e-3)" "unprognostic (2.84e-2)" "unprognostic (3.43e-3)" "unprognostic (2.96e-3)" "unprognostic (4.03e-1)" "unprognostic (1.16e-1)" "unprognostic (4.15e-1)" "unprognostic (7.03e-3)" "unprognostic (2.18e-2)" "unprognostic (2.86e-2)" "validated prognostic favorable (1.03e-8)" "validated prognostic favorable (2.71e-4)" "unprognostic (3.05e-2)" "unprognostic (9.85e-3)" "potential prognostic unfavorable (4.47e-4)" "unprognostic (1.31e-1)" "unprognostic (1.89e-2)" "unprognostic (1.55e-1)" "unprognostic (3.80e-2)" "unprognostic (1.10e-1)" "unprognostic (1.67e-1)" "unprognostic (2.11e-2)" "potential prognostic unfavorable (7.30e-4)" "unprognostic (4.69e-2)" "unprognostic (1.27e-2)" "unprognostic (5.73e-2)" "unprognostic (7.17e-2)" "unprognostic (3.46e-1)" "unprognostic (5.42e-1)" "unprognostic (3.09e-1)" "unprognostic (3.84e-2)" MORF4L2 "KIAA0026, MRGX" ENSG00000123562 "Mortality factor 4 like 2" Q15014 X 103675496-103688158 "Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Growth regulation, Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Decidual stromal cells: 985.7;Extravillous trophoblasts: 1860.3;Migrating cytotrophoblasts: 947.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031872, HPA054102" Supported Enhanced Nucleoplasm NA Yes "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 75: Ovary - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 101 Nucleoplasm "HPA031872: , HPA054102: " "unprognostic (3.07e-1)" "potential prognostic unfavorable (2.18e-4)" "unprognostic (5.02e-3)" "unprognostic (4.80e-2)" "unprognostic (3.48e-1)" "unprognostic (8.63e-2)" "unprognostic (1.62e-1)" "unprognostic (2.75e-3)" "potential prognostic unfavorable (1.33e-4)" "unprognostic (2.99e-2)" "potential prognostic favorable (5.68e-6)" "unprognostic (1.76e-2)" "potential prognostic unfavorable (4.78e-4)" "unprognostic (1.71e-2)" "unprognostic (1.74e-3)" "unprognostic (1.53e-2)" "potential prognostic unfavorable (1.04e-5)" "unprognostic (9.05e-2)" "unprognostic (6.63e-2)" "unprognostic (1.27e-1)" "unprognostic (2.44e-1)" "unprognostic (2.40e-1)" "unprognostic (2.18e-2)" "unprognostic (5.81e-2)" "unprognostic (4.74e-2)" "unprognostic (1.06e-1)" "unprognostic (7.91e-2)" "unprognostic (4.74e-1)" "unprognostic (6.87e-2)" "unprognostic (6.41e-2)" "unprognostic (6.63e-2)" MORN1 FLJ13941 ENSG00000116151 "MORN repeat containing 1" Q5T089 1 2321253-2391707 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.4" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 65.9;Ependymal cells: 84.2;Epididymal efferent duct ciliated cells: 65.5;Fallopian tube ciliated cells: 96.6;Late primary spermatocytes: 62.3;Respiratory ciliated cells: 147.7" "Cell type enhanced" "Detected in all" "ependymal cell: 83.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Region enhanced" "Detected in some" "cerebellum: 4.6" "HPA005858, HPA070703" Uncertain Approved Nucleoplasm,Nucleoli,Mitochondria NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 64: Non-specific - Transcription" "Cluster 2: Neurons - Nucleosome" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" "Nucleoplasm, Mitochondria" Nucleoli "HPA005858: , HPA070703: " "unprognostic (1.51e-1)" "unprognostic (1.35e-2)" "unprognostic (1.19e-2)" "unprognostic (1.00e-1)" "unprognostic (3.01e-1)" "unprognostic (2.64e-2)" "unprognostic (1.45e-1)" "unprognostic (1.02e-1)" "unprognostic (7.28e-2)" "unprognostic (2.65e-1)" "potential prognostic favorable (3.61e-4)" "unprognostic (1.48e-2)" "unprognostic (1.38e-3)" "unprognostic (1.59e-1)" "unprognostic (2.38e-2)" "unprognostic (1.41e-2)" "unprognostic (3.07e-3)" "unprognostic (1.96e-1)" "unprognostic (3.76e-2)" "unprognostic (7.10e-2)" "unprognostic (1.50e-1)" "unprognostic (3.84e-3)" "unprognostic (5.81e-2)" "unprognostic (4.14e-1)" "unprognostic (6.40e-2)" "unprognostic (2.62e-1)" "unprognostic (4.39e-2)" "unprognostic (6.23e-2)" "unprognostic (1.27e-1)" "unprognostic (1.49e-1)" "unprognostic (4.40e-2)" MORN2 MOPT ENSG00000188010 "MORN repeat containing 2" Q502X0 2 38875976-38929072 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 181.8;testis: 170.3" "Cell type enhanced" "Detected in many" "Early spermatids: 2038.3;Endometrial ciliated cells: 742.7;Epididymal efferent duct ciliated cells: 665.2;Fallopian tube ciliated cells: 870.4;Late primary spermatocytes: 1510.3;Late spermatids: 6209.1;Respiratory ciliated cells: 898.2" "Cell type enhanced" "Detected in all" "ependymal cell: 64.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057815 Approved Nucleoplasm NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" 1 Nucleoplasm "HPA057815: " "unprognostic (3.22e-1)" "unprognostic (5.65e-2)" "unprognostic (1.44e-1)" "unprognostic (2.11e-2)" "unprognostic (5.56e-2)" "potential prognostic favorable (5.20e-4)" "unprognostic (7.26e-2)" "unprognostic (6.36e-3)" "unprognostic (1.39e-2)" "unprognostic (2.63e-3)" "unprognostic (2.45e-2)" "unprognostic (1.88e-1)" "unprognostic (1.08e-3)" "potential prognostic unfavorable (2.17e-4)" "unprognostic (1.99e-3)" "unprognostic (3.31e-1)" "unprognostic (2.08e-1)" "unprognostic (1.80e-1)" "unprognostic (4.20e-2)" "unprognostic (8.27e-2)" "unprognostic (1.87e-1)" "unprognostic (1.98e-1)" "unprognostic (6.90e-3)" "unprognostic (1.45e-1)" "unprognostic (3.59e-1)" "unprognostic (3.04e-2)" "unprognostic (1.00e-1)" "unprognostic (1.97e-1)" "unprognostic (1.27e-2)" "unprognostic (1.65e-1)" "unprognostic (2.60e-1)" MORN3 ENSG00000139714 "MORN repeat containing 3" Q6PF18 12 121648742-121672631 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 5.9;fallopian tube: 3.7;testis: 4.3" "Cell type enriched" "Detected in many" 7 "Late spermatids: 3252.5" "Group enriched" "Detected in many" 4 "choroid plexus epithelial cell: 25.8;ependymal cell: 61.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Skin - Keratinocyte (other), Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA038709, HPA038710" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 17: Choroid plexus - Cilium" "Cluster 34: Testis cancer - Unknown function" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 59 Nucleoplasm "Plasma membrane" "HPA038709: , HPA038710: " "unprognostic (9.37e-2)" "unprognostic (4.04e-3)" "unprognostic (7.33e-2)" "unprognostic (1.26e-1)" "unprognostic (1.05e-1)" "unprognostic (7.83e-3)" "unprognostic (1.55e-3)" "potential prognostic unfavorable (8.80e-4)" "potential prognostic favorable (2.58e-4)" "unprognostic (3.64e-2)" "unprognostic (6.13e-2)" "unprognostic (2.10e-1)" "unprognostic (1.09e-2)" "unprognostic (1.06e-2)" "unprognostic (1.48e-1)" "unprognostic (1.09e-1)" "unprognostic (7.10e-2)" "unprognostic (2.92e-1)" MORN4 "bA548K23.4, C10orf83, FLJ25925, rtp" ENSG00000171160 "MORN repeat containing 4" Q8NDC4 10 97614553-97633500 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 45.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052718 Uncertain NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 65: Brain - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 52: Non-specific - Mitochondria" "Cluster 98: Neurons - Neurotransmission & signaling" 28 "HPA052718: " "unprognostic (9.76e-2)" "unprognostic (3.78e-2)" "unprognostic (5.39e-2)" "unprognostic (3.12e-1)" "unprognostic (1.66e-2)" "unprognostic (8.93e-2)" "unprognostic (1.17e-1)" "unprognostic (2.44e-2)" "unprognostic (6.71e-3)" "unprognostic (1.50e-1)" "potential prognostic favorable (3.73e-4)" "unprognostic (1.46e-1)" "potential prognostic favorable (6.90e-4)" "unprognostic (2.45e-1)" "unprognostic (1.72e-2)" "unprognostic (9.06e-2)" "unprognostic (7.58e-2)" "unprognostic (1.07e-2)" "unprognostic (1.59e-2)" "unprognostic (1.31e-1)" "unprognostic (1.05e-1)" "potential prognostic favorable (4.72e-4)" "unprognostic (1.17e-2)" "unprognostic (1.75e-1)" "unprognostic (1.59e-1)" "unprognostic (2.16e-1)" "unprognostic (1.02e-1)" "unprognostic (1.58e-2)" "unprognostic (3.04e-2)" "unprognostic (4.04e-2)" "unprognostic (1.25e-2)" MORN5 "C9orf113, C9orf18, FLJ46909" ENSG00000185681 "MORN repeat containing 5" Q5VZ52 9 122159908-122200088 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 76.5;fallopian tube: 104.3;testis: 78.2" "Group enriched" "Detected in many" 6 "Early spermatids: 439.9;Endometrial ciliated cells: 253.5;Epididymal efferent duct ciliated cells: 373.1;Fallopian tube ciliated cells: 538.5;Late primary spermatocytes: 572.9;Late spermatids: 996.5;Respiratory ciliated cells: 570.8" "Cell type enriched" "Detected in many" 4 "ependymal cell: 112.1" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 9.7;Uterine Corpus Endometrial Carcinoma (TCGA): 12.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Bile duct cancer: 1.1" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" 8 "unprognostic (2.56e-3)" "unprognostic (1.02e-1)" "unprognostic (1.14e-1)" "unprognostic (2.72e-1)" "unprognostic (6.53e-2)" "unprognostic (6.17e-2)" "unprognostic (2.86e-1)" "unprognostic (4.83e-2)" "unprognostic (2.58e-1)" "unprognostic (9.99e-2)" "unprognostic (1.56e-1)" "potential prognostic favorable (1.20e-4)" "unprognostic (1.13e-2)" "unprognostic (1.58e-1)" MOS ENSG00000172680 "MOS proto-oncogene, serine/threonine kinase" P00540 8 56112942-56113982 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Proto-oncogene" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Early spermatids: 6.4;Late primary spermatocytes: 9.9;Microglia: 1.9;Oocytes: 4.6" "Group enriched" "Detected in some" 4 "central nervous system macrophage: 2.1;deep-layer near-projecting: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 4: Non-specific - Transcription" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 59 MOSMO "ATTHOG, BC030336, C16orf52" ENSG00000185716 "Modulator of smoothened" Q8NHV5 16 22007638-22087534 "Predicted membrane proteins" Differentiation "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 82.9;Bergmann glia: 89.9;Brain excitatory neurons: 146.3;Brain inhibitory neurons: 140.0;Choroid plexus epithelial cells: 113.9;Distal convoluted tubule cells: 75.1;Ependymal cells: 57.9;Loop of henle epithelial cells: 69.7;Microglia: 87.0;Oligodendrocyte progenitor cells: 103.9;Oligodendrocytes: 88.4;Other brain neurons: 116.6;Papillary tip epithelial cells: 64.4;Podocytes: 94.7;Proximal tubule cells: 68.9;Renal collecting duct intercalated cells: 65.9;Renal collecting duct principal cells: 64.0;Renal connecting tubule cells: 74.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 102: Non-specific - Mixed function" "unprognostic (2.80e-2)" "unprognostic (1.43e-1)" "unprognostic (1.47e-1)" "unprognostic (2.51e-2)" "unprognostic (1.48e-1)" "unprognostic (4.32e-1)" "unprognostic (1.22e-1)" "unprognostic (3.41e-3)" "unprognostic (1.50e-3)" "validated prognostic favorable (4.67e-5)" "validated prognostic favorable (7.08e-4)" "unprognostic (1.96e-1)" "unprognostic (3.11e-1)" "unprognostic (4.27e-3)" "unprognostic (5.37e-2)" "unprognostic (2.73e-1)" "unprognostic (1.33e-2)" "unprognostic (3.47e-2)" "unprognostic (1.56e-2)" "unprognostic (5.28e-2)" "potential prognostic unfavorable (2.25e-4)" "unprognostic (8.75e-2)" "unprognostic (1.40e-2)" "unprognostic (8.88e-3)" "unprognostic (2.14e-1)" "unprognostic (2.29e-2)" "unprognostic (2.25e-1)" "unprognostic (1.37e-2)" "unprognostic (8.08e-2)" MOSPD1 dJ473B4 ENSG00000101928 "Motile sperm domain containing 1" Q9UJG1 X 134887632-134915257 "Predicted intracellular proteins, Predicted membrane proteins" Differentiation "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 128.7;Endometrial ciliated cells: 107.5;Epididymal efferent duct ciliated cells: 85.2;Esophageal apical cells: 273.4;Fallopian tube ciliated cells: 166.1;Late primary spermatocytes: 96.1;Late spermatids: 162.3" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 69.2" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "choroid plexus: 21.0" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031158 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 21: Non-specific - Metabolism" "Cluster 36: Non-specific - mRNA processing" "Cluster 84: Apical squamous epithelium - Cornification" 1 "Nucleoplasm, Vesicles" "HPA031158: " "unprognostic (1.15e-1)" "potential prognostic unfavorable (4.18e-4)" "unprognostic (8.04e-2)" "unprognostic (7.99e-2)" "unprognostic (3.02e-1)" "unprognostic (1.14e-1)" "unprognostic (1.52e-1)" "unprognostic (1.61e-1)" "unprognostic (4.54e-1)" "unprognostic (2.59e-3)" "potential prognostic favorable (4.31e-6)" "unprognostic (1.42e-2)" "unprognostic (5.56e-2)" "unprognostic (7.17e-3)" "unprognostic (9.95e-3)" "unprognostic (1.08e-1)" "unprognostic (2.05e-1)" "unprognostic (3.99e-1)" "unprognostic (1.14e-1)" "unprognostic (2.89e-1)" "unprognostic (3.43e-2)" "unprognostic (4.12e-3)" "unprognostic (1.23e-3)" "unprognostic (3.94e-2)" "unprognostic (1.91e-1)" "unprognostic (1.36e-1)" "unprognostic (1.30e-1)" "unprognostic (1.01e-3)" "unprognostic (9.80e-2)" "unprognostic (9.78e-2)" "unprognostic (9.43e-2)" MOSPD2 MGC26706 ENSG00000130150 "Motile sperm domain containing 2" Q8NHP6 X 14873421-14922327 "Predicted intracellular proteins, Predicted membrane proteins" Chemotaxis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophil progenitors: 108.0;Neutrophils: 205.8;Oligodendrocytes: 128.0" "Cell type enhanced" "Detected in all" "oligodendrocyte: 187.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 53.6" "Group enriched" "Detected in all" 6 "granulocytes: 53.6;monocytes: 15.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003334 Uncertain Supported "Endoplasmic reticulum" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 14 "Endoplasmic reticulum" "HPA003334: " "unprognostic (4.49e-3)" "unprognostic (5.72e-3)" "unprognostic (1.63e-1)" "unprognostic (3.58e-2)" "unprognostic (1.40e-1)" "unprognostic (6.23e-2)" "unprognostic (1.19e-1)" "unprognostic (7.91e-3)" "unprognostic (1.17e-1)" "unprognostic (3.64e-3)" "potential prognostic favorable (1.76e-4)" "unprognostic (3.45e-1)" "unprognostic (6.64e-3)" "unprognostic (3.95e-3)" "unprognostic (2.08e-1)" "unprognostic (6.56e-2)" "unprognostic (9.26e-2)" "unprognostic (2.23e-1)" "unprognostic (2.42e-1)" "unprognostic (2.35e-1)" "unprognostic (7.36e-2)" "unprognostic (4.99e-2)" "unprognostic (7.84e-3)" "unprognostic (1.00e-1)" "unprognostic (2.70e-2)" "unprognostic (3.44e-2)" "unprognostic (1.35e-1)" "unprognostic (9.74e-2)" "unprognostic (2.92e-1)" "unprognostic (1.27e-1)" "unprognostic (1.67e-2)" MOSPD3 "CDS3, NET30" ENSG00000106330 "Motile sperm domain containing 3" O75425 7 100612102-100615384 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "Late spermatids: 2548.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041137 Uncertain Approved Cytosol NA No "Cluster 9: T-regs - Cell cycle regulation" "Cluster 47: Testis - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 13 Cytosol "HPA041137: " "potential prognostic favorable (2.57e-5)" "unprognostic (1.10e-1)" "unprognostic (2.06e-1)" "unprognostic (3.19e-3)" "unprognostic (9.83e-3)" "unprognostic (3.25e-1)" "unprognostic (3.47e-3)" "unprognostic (6.64e-2)" "unprognostic (2.38e-1)" "unprognostic (5.99e-3)" "unprognostic (3.58e-2)" "unprognostic (1.57e-1)" "potential prognostic favorable (6.93e-4)" "unprognostic (3.11e-1)" "unprognostic (2.85e-2)" "unprognostic (2.40e-1)" "unprognostic (5.44e-2)" "unprognostic (3.15e-1)" "unprognostic (1.53e-1)" "unprognostic (2.84e-1)" "unprognostic (3.31e-2)" "unprognostic (2.83e-1)" "unprognostic (4.17e-2)" "unprognostic (3.12e-1)" "unprognostic (2.93e-2)" "unprognostic (1.45e-2)" "unprognostic (2.29e-1)" "unprognostic (5.13e-2)" "unprognostic (6.27e-2)" "unprognostic (4.33e-3)" "unprognostic (4.64e-1)" MOV10 "fSAP113, gb110, MGC2948" ENSG00000155363 "Mov10 RISC complex RNA helicase" Q9HCE1 1 112673141-112700756 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, RNA-mediated gene silencing, Transcription, Transcription regulation" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 66.1;Sertoli cells: 144.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA031627 Approved Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 77: Intestine - Digestion" "Cluster 46: Brainstem - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 123 Cytosol "HPA031627: " "unprognostic (3.77e-1)" "unprognostic (7.13e-2)" "unprognostic (3.02e-2)" "unprognostic (2.87e-1)" "unprognostic (4.48e-3)" "unprognostic (9.85e-2)" "unprognostic (8.44e-2)" "unprognostic (1.98e-1)" "unprognostic (5.92e-2)" "unprognostic (7.43e-2)" "unprognostic (8.56e-3)" "unprognostic (1.83e-1)" "unprognostic (2.13e-2)" "unprognostic (1.51e-3)" "unprognostic (2.69e-1)" "potential prognostic unfavorable (4.38e-4)" "unprognostic (5.86e-2)" "unprognostic (5.32e-1)" "unprognostic (1.74e-1)" "unprognostic (7.29e-2)" "potential prognostic favorable (2.77e-4)" "unprognostic (9.64e-3)" "potential prognostic unfavorable (5.44e-4)" "unprognostic (8.24e-2)" "unprognostic (4.15e-3)" "unprognostic (9.10e-2)" "unprognostic (8.99e-2)" "unprognostic (5.32e-2)" "unprognostic (1.58e-1)" "unprognostic (2.79e-2)" "unprognostic (8.60e-2)" MOV10L1 "CHAMP, DJ402G11.8, DKFZp434B0717" ENSG00000073146 "Mov10 like RISC complex RNA helicase 1" Q9BXT6 22 50089879-50161690 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Developmental protein, Helicase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "testis: 41.3" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 76.6;Early primary spermatocytes: 167.4;Early spermatids: 155.2;Late primary spermatocytes: 66.0;Late spermatids: 451.1;Undifferentiated spermatogonia: 57.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" HPA019034 Approved NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" "HPA019034: " "unprognostic (2.11e-1)" "unprognostic (8.71e-3)" "unprognostic (2.63e-2)" "unprognostic (1.69e-1)" "unprognostic (1.19e-1)" "unprognostic (2.09e-2)" MOXD1 "dJ248E1.1, DKFZP564G202, MOX" ENSG00000079931 "Monooxygenase DBH like 1" Q6UVY6 6 132296055-132401475 "Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 59.9;smooth muscle: 73.5" "Cell type enhanced" "Detected in many" "Astrocytes: 73.2;Decidual stromal cells: 132.8;Early spermatids: 127.8;Endometrial stromal cells: 95.5;Esophageal basal cells: 92.9;Fibroblasts: 70.0;Müller glia: 46.7;Pituicytes/FSCs: 262.4;Salivary myoepithelial cells: 130.5" "Cell type enhanced" "Detected in many" "amygdala excitatory: 94.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 33 "memory B-cell: 3.1;naive B-cell: 1.7;plasmacytoid DC: 5.1" "Group enriched" "Detected in many" 41 "B-cells: 3.1;dendritic cells: 5.1" "Cancer enhanced" "Detected in many" "skin cancer: 61.1" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Fibroblasts, Colon - Enteric glia cells, Kidney - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035740 Approved Approved Cytosol NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 75: Ovary - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 5 Cytosol "HPA035740: " "unprognostic (1.41e-2)" "unprognostic (1.14e-1)" "unprognostic (2.39e-1)" "unprognostic (3.04e-2)" "unprognostic (5.83e-2)" "unprognostic (1.56e-1)" "unprognostic (4.46e-2)" "potential prognostic unfavorable (1.01e-5)" "potential prognostic favorable (3.75e-4)" "unprognostic (5.42e-2)" "unprognostic (9.01e-2)" "unprognostic (2.41e-3)" "unprognostic (2.06e-3)" "unprognostic (1.01e-1)" "unprognostic (2.66e-2)" "unprognostic (1.33e-1)" "unprognostic (1.97e-1)" "unprognostic (4.23e-2)" "unprognostic (6.60e-3)" "unprognostic (4.68e-2)" "potential prognostic unfavorable (2.33e-5)" "unprognostic (1.61e-1)" "unprognostic (1.39e-1)" "unprognostic (7.59e-2)" "unprognostic (1.71e-1)" "unprognostic (7.09e-3)" "unprognostic (6.99e-2)" "unprognostic (1.06e-3)" "unprognostic (5.33e-2)" "unprognostic (6.94e-2)" "unprognostic (9.07e-2)" MPC1 "BRP44L, CGI-129, dJ68L15.3, SLC54A1" ENSG00000060762 "Mitochondrial pyruvate carrier 1" Q9Y5U8 6 166364919-166383013 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 692.4;tongue: 521.3" "Cell type enhanced" "Detected in all" "Epididymal clear cells: 481.8;Hepatocytes: 480.3;Parietal cells: 1069.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045119, HPA055790" Enhanced Enhanced "Mitochondria,Principal piece" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 97: Non-specific - Cellular respiration" 3 Mitochondria "Principal piece" "HPA045119: , HPA055790: " "unprognostic (2.16e-1)" "potential prognostic unfavorable (4.03e-4)" "unprognostic (2.68e-3)" "unprognostic (1.26e-2)" "unprognostic (2.08e-1)" "unprognostic (2.53e-2)" "unprognostic (1.76e-3)" "unprognostic (6.92e-2)" "unprognostic (2.24e-1)" "potential prognostic favorable (1.71e-7)" "unprognostic (2.59e-3)" "potential prognostic favorable (2.35e-4)" "unprognostic (5.25e-2)" "unprognostic (3.74e-3)" "unprognostic (1.13e-2)" "unprognostic (1.27e-1)" "unprognostic (4.95e-2)" "unprognostic (6.59e-2)" "unprognostic (1.63e-1)" "unprognostic (2.96e-3)" "unprognostic (9.79e-2)" "unprognostic (1.66e-2)" "unprognostic (1.69e-1)" "unprognostic (1.29e-1)" "unprognostic (2.77e-1)" "unprognostic (4.96e-2)" "unprognostic (8.75e-2)" "unprognostic (3.56e-2)" "unprognostic (6.46e-2)" MPC1L SLC54A3 ENSG00000238205 "Mitochondrial pyruvate carrier 1 like" P0DKB6 X 40623428-40624136 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 174 "testis: 17.3" "Cell type enhanced" "Detected in some" "Early spermatids: 176.3;Late primary spermatocytes: 108.7;Late spermatids: 577.6;Oocytes: 64.5" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 8 "Testicular Germ Cell Tumor (TCGA): 2.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 4: Non-specific - Transcription" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 1 "unprognostic (3.19e-1)" MPC2 "BRP44, DKFZP564B167, SLC54A2" ENSG00000143158 "Mitochondrial pyruvate carrier 2" O95563 1 167916675-167937072 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 2282.5;Late primary spermatocytes: 2120.2;Late spermatids: 8598.6;Parietal cells: 947.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056091 Uncertain NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 76: Non-specific - Metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 17 "HPA056091: " "unprognostic (4.45e-2)" "unprognostic (6.63e-2)" "unprognostic (2.78e-1)" "unprognostic (2.43e-3)" "unprognostic (2.33e-1)" "unprognostic (9.09e-2)" "unprognostic (7.82e-2)" "unprognostic (6.22e-2)" "unprognostic (1.03e-3)" "potential prognostic favorable (1.42e-5)" "unprognostic (6.46e-2)" "unprognostic (1.80e-2)" "unprognostic (9.09e-2)" "unprognostic (7.76e-2)" "unprognostic (3.06e-1)" "unprognostic (3.73e-1)" "unprognostic (3.50e-1)" "unprognostic (5.08e-3)" "unprognostic (5.46e-2)" "unprognostic (1.30e-2)" "unprognostic (8.12e-3)" "unprognostic (3.91e-2)" "unprognostic (3.24e-1)" "unprognostic (8.78e-2)" "unprognostic (2.98e-2)" "unprognostic (3.97e-1)" "unprognostic (1.74e-1)" "unprognostic (2.93e-1)" "unprognostic (1.49e-1)" MPDU1 "CDGIf, Lec35, PQLC5, SL15, SLC66A5" ENSG00000129255 "Mannose-P-dolichol utilization defect 1" O75352 17 7583529-7592789 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Transport "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 142.0;Esophageal apical cells: 143.3;Syncytiotrophoblasts: 199.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014845 Uncertain Supported "Endoplasmic reticulum,Mitochondria" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 21: Non-specific - Metabolism" "Cluster 42: Non-specific - Unknown function" "Cluster 65: Non-specific - Cell growth & division" 14 "Endoplasmic reticulum" Mitochondria "HPA014845: " "unprognostic (1.42e-2)" "unprognostic (8.23e-2)" "unprognostic (1.87e-2)" "unprognostic (2.02e-1)" "unprognostic (3.39e-1)" "unprognostic (2.18e-3)" "unprognostic (1.38e-1)" "unprognostic (3.01e-2)" "unprognostic (1.00e-1)" "unprognostic (1.54e-2)" "unprognostic (2.00e-2)" "unprognostic (1.92e-1)" "potential prognostic favorable (6.55e-7)" "unprognostic (3.11e-1)" "unprognostic (2.80e-2)" "unprognostic (9.87e-3)" "unprognostic (1.04e-1)" "unprognostic (2.45e-1)" "unprognostic (9.41e-2)" "unprognostic (1.34e-1)" "unprognostic (2.04e-1)" "unprognostic (4.89e-2)" "unprognostic (7.34e-2)" "unprognostic (1.95e-1)" "unprognostic (3.73e-1)" "unprognostic (1.57e-1)" "unprognostic (3.45e-1)" "unprognostic (2.03e-1)" "unprognostic (2.35e-1)" "unprognostic (1.56e-1)" "unprognostic (1.38e-2)" MPDZ MUPP1 ENSG00000107186 "Multiple PDZ domain crumbs cell polarity complex component" O75970 9 13105706-13279692 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 80.1" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 399.1;Ependymal cells: 595.9;Lactotrophs: 336.0;Pituicytes/FSCs: 315.1;Retinal pigment epithelial cells: 400.7;Thyrotrophs: 318.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Prostate - Smooth muscle cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013512, HPA020255, HPA026686" Uncertain Approved "Centriolar satellite,Basal body" NA NA "Cluster 16: Liver & Kidney - Metabolism" "Cluster 46: Brainstem - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 23 "Centriolar satellite" "Basal body" "CAB013512: , HPA020255: , HPA026686: " "unprognostic (2.30e-2)" "unprognostic (2.16e-1)" "unprognostic (2.98e-1)" "unprognostic (4.90e-3)" "unprognostic (2.15e-2)" "unprognostic (1.81e-1)" "unprognostic (1.81e-2)" "unprognostic (3.47e-1)" "unprognostic (1.55e-1)" "unprognostic (1.06e-1)" "potential prognostic favorable (5.43e-7)" "unprognostic (1.87e-3)" "unprognostic (6.56e-2)" "unprognostic (5.20e-2)" "potential prognostic favorable (4.79e-5)" "unprognostic (9.02e-2)" "unprognostic (1.39e-1)" "unprognostic (5.92e-2)" "unprognostic (4.21e-1)" "unprognostic (2.49e-1)" "unprognostic (2.41e-2)" "unprognostic (2.09e-2)" "unprognostic (1.06e-1)" "unprognostic (4.16e-1)" "unprognostic (1.39e-1)" "unprognostic (5.47e-2)" "unprognostic (1.26e-1)" "unprognostic (2.01e-3)" "unprognostic (2.07e-1)" "unprognostic (8.15e-2)" "unprognostic (2.04e-1)" MPEG1 MPG1 ENSG00000197629 "Macrophage expressed 1" Q2M385 11 59208510-59212927 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Adaptive immunity, Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 193.5" "Cell type enhanced" "Detected in some" "cDC: 121.2;Hofbauer cells: 99.6;Kupffer cells: 582.1;Macrophages: 194.7;Monocyte progenitors: 72.8;monocytes: 371.2;pDCs: 266.3" "Group enriched" "Detected in some" 67 "central nervous system macrophage: 39.0;leukocyte: 22.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 289.4;intermediate monocyte: 209.0;myeloid DC: 144.2;non-classical monocyte: 245.5;plasmacytoid DC: 204.5" "Group enriched" "Detected in many" 6 "dendritic cells: 204.5;monocytes: 289.4" "Group enriched" "Detected in some" 237 "Leukemia: 10.4;lymphoma: 36.9" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Skeletal muscle - Macrophages, Spleen - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046801 Approved "Secreted to blood" Immunity NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" "HPA046801: " "unprognostic (2.54e-1)" "unprognostic (1.07e-1)" "unprognostic (1.94e-2)" "unprognostic (4.23e-2)" "unprognostic (1.56e-1)" "unprognostic (1.38e-1)" "unprognostic (2.18e-2)" "unprognostic (2.35e-1)" "unprognostic (2.71e-3)" "unprognostic (4.95e-2)" "potential prognostic favorable (4.66e-4)" "unprognostic (8.35e-2)" "unprognostic (6.23e-3)" "unprognostic (9.00e-2)" "unprognostic (1.71e-2)" "potential prognostic favorable (2.57e-4)" "unprognostic (2.30e-2)" "unprognostic (3.01e-1)" "unprognostic (1.06e-2)" "unprognostic (4.36e-1)" "unprognostic (3.09e-1)" "unprognostic (2.82e-2)" "unprognostic (2.00e-1)" "unprognostic (2.35e-1)" "unprognostic (1.26e-2)" "unprognostic (5.58e-2)" "unprognostic (1.52e-1)" "unprognostic (9.30e-2)" "unprognostic (4.30e-2)" "unprognostic (2.55e-1)" "unprognostic (6.18e-2)" MPG MDG ENSG00000103152 "N-methylpurine DNA glycosylase" P29372 16 77007-85851 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006531 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 24: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 54: Non-specific - Transcription" "Cluster 108: Fibroblasts - ECM organization" 11 Nucleoplasm Cytosol "HPA006531: " "unprognostic (2.51e-1)" "unprognostic (2.11e-2)" "unprognostic (3.37e-2)" "unprognostic (4.16e-1)" "unprognostic (4.31e-2)" "unprognostic (3.96e-1)" "unprognostic (5.11e-2)" "unprognostic (4.90e-1)" "unprognostic (1.64e-1)" "unprognostic (1.44e-1)" "validated prognostic unfavorable (3.91e-4)" "validated prognostic unfavorable (2.94e-7)" "unprognostic (2.88e-1)" "unprognostic (1.34e-2)" "unprognostic (6.85e-3)" "unprognostic (1.80e-1)" "unprognostic (4.65e-2)" "unprognostic (2.38e-1)" "unprognostic (2.48e-1)" "unprognostic (2.48e-1)" "unprognostic (1.33e-1)" "unprognostic (3.31e-2)" "unprognostic (2.78e-1)" "unprognostic (1.14e-1)" "unprognostic (2.97e-1)" "unprognostic (1.37e-1)" "unprognostic (4.57e-2)" "unprognostic (3.09e-3)" "unprognostic (7.76e-2)" "unprognostic (3.32e-2)" "unprognostic (9.56e-3)" MPHOSPH10 "CT90, MPP10, MPP10P, PPP1R106" ENSG00000124383 "M-phase phosphoprotein 10" O00566 2 71130310-71150101 "Essential proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ribosome biogenesis, rRNA processing" Ribonucleoprotein "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035059, HPA035060, HPA049907" Enhanced Enhanced "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 3: Non-specific - Nuclear processes" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 17: Non-specific - RNA processing" 79 "Nucleoli, Nucleoli rim" "Mitotic chromosome" "HPA035059: , HPA035060: , HPA049907: " "unprognostic (2.95e-1)" "potential prognostic unfavorable (6.03e-4)" "unprognostic (2.12e-1)" "unprognostic (4.02e-2)" "unprognostic (7.02e-3)" "unprognostic (1.07e-1)" "unprognostic (1.00e-1)" "unprognostic (4.48e-2)" "unprognostic (1.01e-1)" "unprognostic (3.01e-2)" "unprognostic (1.26e-1)" "unprognostic (1.71e-1)" "potential prognostic unfavorable (1.94e-4)" "unprognostic (2.20e-3)" "unprognostic (4.26e-3)" "unprognostic (2.38e-2)" "unprognostic (4.38e-2)" "unprognostic (3.98e-2)" "unprognostic (4.88e-2)" "unprognostic (2.14e-1)" "unprognostic (3.23e-2)" "unprognostic (4.00e-2)" "unprognostic (9.02e-3)" "unprognostic (4.61e-2)" "unprognostic (1.69e-1)" "unprognostic (4.67e-2)" "unprognostic (1.36e-2)" "unprognostic (1.34e-1)" "unprognostic (2.11e-1)" "unprognostic (9.30e-2)" "unprognostic (1.71e-1)" MPHOSPH6 MPP6 ENSG00000135698 "M-phase phosphoprotein 6" Q99547 16 82147798-82170224 "Predicted intracellular proteins" "rRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Breast lactating cells: 186.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003674, HPA026948" Approved Supported Nucleoplasm,Nucleoli No No "Cluster 3: Non-specific - Nuclear processes" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 49 "Nucleoplasm, Nucleoli" "CAB003674: , HPA026948: " "unprognostic (5.29e-2)" "unprognostic (1.08e-3)" "unprognostic (3.29e-1)" "unprognostic (2.73e-2)" "unprognostic (1.74e-1)" "unprognostic (2.70e-1)" "unprognostic (6.91e-2)" "unprognostic (5.19e-2)" "unprognostic (4.09e-3)" "unprognostic (9.91e-3)" "unprognostic (6.34e-3)" "unprognostic (1.73e-2)" "unprognostic (2.18e-2)" "potential prognostic unfavorable (7.10e-7)" "unprognostic (8.68e-3)" "unprognostic (3.68e-2)" "unprognostic (1.92e-2)" "unprognostic (6.10e-2)" "unprognostic (2.10e-1)" "potential prognostic favorable (5.55e-4)" "unprognostic (4.73e-2)" "unprognostic (3.66e-2)" "potential prognostic unfavorable (1.70e-6)" "potential prognostic unfavorable (6.41e-4)" "unprognostic (6.74e-2)" "unprognostic (2.77e-2)" "unprognostic (5.95e-2)" "unprognostic (3.18e-1)" "unprognostic (1.62e-1)" "unprognostic (3.70e-1)" "unprognostic (2.58e-1)" MPHOSPH8 "HSMPP8, mpp8" ENSG00000196199 "M-phase phosphoprotein 8" Q99549 13 19633659-19673441 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039701, HPA040035" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 32: Basophils - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 19: Non-specific - Unknown function" "Cluster 94: Gonadal somatic cells - Mixed function" 29 Nucleoplasm "Plasma membrane, Cytosol" "HPA039701: , HPA040035: " "unprognostic (1.79e-2)" "unprognostic (5.06e-2)" "unprognostic (6.78e-2)" "unprognostic (1.55e-2)" "unprognostic (7.66e-2)" "unprognostic (7.22e-2)" "unprognostic (7.19e-2)" "unprognostic (9.58e-2)" "unprognostic (1.88e-1)" "unprognostic (2.45e-2)" "validated prognostic favorable (1.34e-5)" "validated prognostic favorable (2.86e-4)" "potential prognostic favorable (4.72e-4)" "potential prognostic unfavorable (1.86e-4)" "unprognostic (1.76e-2)" "unprognostic (8.59e-2)" "unprognostic (5.96e-2)" "unprognostic (1.56e-1)" "unprognostic (1.59e-1)" "unprognostic (6.21e-3)" "unprognostic (8.86e-3)" "unprognostic (2.87e-2)" "unprognostic (3.08e-2)" "unprognostic (1.70e-1)" "unprognostic (4.46e-2)" "unprognostic (9.02e-2)" "unprognostic (9.42e-2)" "unprognostic (3.82e-2)" "unprognostic (2.72e-1)" "unprognostic (2.00e-1)" "unprognostic (1.01e-1)" MPHOSPH9 MPP9 ENSG00000051825 "M-phase phosphoprotein 9" Q99550 12 123152320-123244014 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 30.5" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037485 Approved Uncertain "Nucleoplasm,Golgi apparatus,Plasma membrane,Centrosome,Basal body,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 59: Leukemia - T-cell receptor" "Cluster 27: Non-specific - Cell proliferation" 18 "Plasma membrane, Cytosol" "Nucleoplasm, Golgi apparatus, Centrosome, Basal body" "HPA037485: " "unprognostic (5.47e-3)" "unprognostic (4.73e-3)" "unprognostic (1.99e-1)" "unprognostic (2.76e-1)" "unprognostic (4.13e-2)" "unprognostic (1.83e-2)" "unprognostic (1.73e-1)" "unprognostic (1.28e-3)" "unprognostic (1.62e-1)" "unprognostic (1.58e-3)" "unprognostic (6.25e-2)" "unprognostic (6.79e-3)" "unprognostic (1.02e-1)" "potential prognostic unfavorable (4.98e-5)" "unprognostic (1.87e-1)" "unprognostic (1.40e-2)" "unprognostic (5.12e-2)" "unprognostic (2.05e-2)" "unprognostic (7.37e-3)" "unprognostic (2.11e-1)" "unprognostic (6.53e-2)" "unprognostic (4.56e-3)" "unprognostic (4.05e-3)" "unprognostic (1.29e-2)" "unprognostic (2.04e-2)" "unprognostic (1.80e-1)" "unprognostic (1.32e-1)" "unprognostic (2.46e-1)" "unprognostic (1.59e-1)" "unprognostic (7.20e-3)" "unprognostic (1.88e-1)" MPI ENSG00000178802 "Mannose phosphate isomerase" P34949 15 74890005-74902219 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Isomerase "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 171.3;Enterocytes: 65.0;Esophageal apical cells: 70.4;Late primary spermatocytes: 60.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007200 Approved Approved "Plasma membrane,Cytosol" NA NA 160000 "Cluster 33: Non-specific - ATP binding" "Cluster 52: Non-specific - Cellular respiration" "Cluster 45: Non-specific - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 3 Cytosol "Plasma membrane" "HPA007200: " "unprognostic (2.90e-1)" "unprognostic (1.81e-1)" "unprognostic (3.04e-1)" "unprognostic (3.73e-2)" "unprognostic (1.23e-1)" "unprognostic (5.46e-2)" "unprognostic (1.93e-2)" "unprognostic (1.22e-1)" "unprognostic (2.37e-3)" "unprognostic (4.45e-2)" "validated prognostic favorable (3.09e-7)" "validated prognostic favorable (8.20e-4)" "unprognostic (1.27e-2)" "unprognostic (2.15e-1)" "potential prognostic unfavorable (5.50e-4)" "unprognostic (6.50e-2)" "unprognostic (3.72e-3)" "unprognostic (3.53e-2)" "unprognostic (1.54e-1)" "unprognostic (2.06e-1)" "unprognostic (2.94e-2)" "unprognostic (4.03e-1)" "unprognostic (3.97e-2)" "unprognostic (1.74e-1)" "unprognostic (1.53e-1)" "unprognostic (1.33e-1)" "unprognostic (1.24e-1)" "unprognostic (4.27e-2)" "unprognostic (1.47e-1)" "unprognostic (2.20e-1)" "unprognostic (4.07e-3)" MPIG6B "C6orf25, G6b, G6b-B, NG31" ENSG00000204420 "Megakaryocyte and platelet inhibitory receptor G6b" O95866 6 31718594-31726714 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Heparin-binding, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 4.5;skin 1: 7.7" "Group enriched" "Detected in some" 7 "Megakaryocytes: 18.5;Platelets: 59.1" "Cell type enhanced" "Detected in single" "pericyte: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "NK-cell: 1.6" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in single" 5 "Leukemia: 1.6" "Adipose subcutaneous - Mast cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA054404, HPA073017" Approved "Nucleoplasm,Endoplasmic reticulum,Golgi apparatus,Plasma membrane,Cytosol" "Intracellular and membrane" Receptor NA NA 360000 "Cluster 37: Skin - Keratinization" "Cluster 47: Leukemia - Hemostasis" "Cluster 47: Platelets - Hemostasis" "Golgi apparatus" "Nucleoplasm, Endoplasmic reticulum, Plasma membrane, Cytosol" "HPA054404: , HPA073017: " MPL "CD110, THPOR, TPOR" ENSG00000117400 "MPL proto-oncogene, thrombopoietin receptor" P40238 1 43337818-43354466 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 14.8;Hematopoietic stem cells: 40.3;Megakaryocyte progenitors: 44.2;Megakaryocytes: 30.9;Platelets: 111.2;Thymocytes: 10.2" "Cell type enhanced" "Detected in some" "ependymal cell: 3.1;upper-layer intratelencephalic: 4.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.4" "Cancer enriched" "Detected in single" 9 "Leukemia: 5.9" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Region enhanced" "Detected in single" "cerebral cortex: 1.5" "Low region specificity" "Detected in many" HPA007619 Supported "Nuclear membrane,Plasma membrane" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 40: Non-specific - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 47: Leukemia - Hemostasis" "Cluster 47: Platelets - Hemostasis" 3 "Plasma membrane" "Nuclear membrane" "HPA007619: " "unprognostic (1.08e-2)" "unprognostic (6.27e-2)" "potential prognostic favorable (1.69e-4)" "unprognostic (1.46e-1)" "unprognostic (9.80e-3)" MPLKIP "C7orf11, ORF20, TTDN1" ENSG00000168303 "M-phase specific PLK1 interacting protein" Q8TAP9 7 40126027-40134622 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058457, HPA065463" Uncertain Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 48: Non-specific - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 8 Nucleoplasm "Golgi apparatus, Vesicles" "HPA058457: , HPA065463: " "unprognostic (2.68e-1)" "unprognostic (1.16e-1)" "unprognostic (6.27e-3)" "unprognostic (1.16e-2)" "unprognostic (6.48e-2)" "potential prognostic unfavorable (6.75e-4)" "unprognostic (3.66e-1)" "unprognostic (4.37e-3)" "unprognostic (3.31e-3)" "unprognostic (2.31e-2)" "unprognostic (1.36e-1)" "unprognostic (1.72e-1)" "unprognostic (2.93e-1)" "unprognostic (1.11e-3)" "unprognostic (6.31e-2)" "unprognostic (7.93e-3)" "unprognostic (7.98e-3)" "unprognostic (1.19e-1)" "unprognostic (7.63e-2)" "unprognostic (1.39e-2)" "unprognostic (1.06e-2)" "unprognostic (5.65e-2)" "unprognostic (4.22e-3)" "unprognostic (1.87e-1)" "unprognostic (6.02e-2)" "unprognostic (1.62e-1)" "unprognostic (7.95e-3)" "unprognostic (1.23e-2)" "unprognostic (6.95e-2)" MPND FLJ14981 ENSG00000008382 "MPN domain containing" Q8N594 19 4343527-4360086 "Enzymes, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 70.9;Enterocytes: 50.1;Megakaryocytes: 49.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043274, HPA045475" Approved Approved "Nucleoplasm,Nucleoli rim" No No "Cluster 10: Non-specific - Membrane trafficking" "Cluster 70: Non-specific - Protein processing" "Cluster 37: Neurons - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 15 "Nucleoli rim" Nucleoplasm "HPA043274: , HPA045475: " "unprognostic (2.50e-3)" "unprognostic (1.55e-2)" "unprognostic (5.86e-2)" "unprognostic (1.34e-2)" "unprognostic (2.09e-1)" "unprognostic (5.30e-2)" "unprognostic (1.50e-1)" "unprognostic (5.53e-2)" "unprognostic (1.60e-2)" "unprognostic (5.03e-3)" "potential prognostic favorable (7.56e-4)" "unprognostic (2.38e-1)" "potential prognostic favorable (1.76e-6)" "unprognostic (9.13e-2)" "unprognostic (2.61e-1)" "unprognostic (1.34e-2)" "unprognostic (4.53e-1)" "unprognostic (3.03e-2)" "unprognostic (3.80e-2)" "unprognostic (1.49e-1)" "unprognostic (6.41e-3)" "unprognostic (1.52e-1)" "unprognostic (5.36e-2)" "unprognostic (7.55e-2)" "unprognostic (1.29e-1)" "unprognostic (2.19e-1)" "unprognostic (3.25e-1)" "potential prognostic favorable (4.11e-4)" "unprognostic (1.22e-1)" "unprognostic (6.19e-1)" "unprognostic (6.68e-3)" MPO ENSG00000005381 Myeloperoxidase P05164 17 58269855-58280935 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrogen peroxide" "Oxidoreductase, Peroxidase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 158 "bone marrow: 3249.5" "Group enriched" "Detected in some" 61 "Monocyte progenitors: 2629.0;Neutrophil progenitors: 2271.8" "Cell type enhanced" "Detected in some" "leukocyte: 2.5" "Cancer enhanced" "Detected in single" "Stomach Adenocarcinoma (TCGA): 2.0" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "classical monocyte: 1.2" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in some" 776 "Leukemia: 854.7" "Lung - Neutrophils_1, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Somatotropes, Spleen - Neutrophils_1" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000059, HPA021147, HPA061464, CAB080352, CAB080353, CAB080354" Enhanced Supported Nucleoplasm,Vesicles "Intracellular and membrane" Enzyme No NA 81000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 15: Bone marrow - Innate immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 4 Vesicles Nucleoplasm "CAB000059: , CAB080352: , CAB080353: , CAB080354: , HPA021147: , HPA061464: " "potential prognostic unfavorable (7.87e-4)" MPP1 "DXS552E, PEMP" ENSG00000130830 "MAGUK p55 scaffold protein 1" Q00013 X 154778684-154821007 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 110.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 528.4;Erythrocyte progenitors: 184.6;Erythrocytes: 305.6;Hofbauer cells: 412.4;Megakaryocytes: 463.6;Migrating cytotrophoblasts: 211.1;Neutrophils: 297.6;Platelets: 1825.7;Syncytiotrophoblasts: 518.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 216.2;neutrophil: 203.0" "Group enriched" "Detected in all" 8 "dendritic cells: 57.8;granulocytes: 216.2;monocytes: 99.4" "Cancer enhanced" "Detected in many" "Leukemia: 109.3" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Lung - Neutrophils_2, Prostate - Smooth muscle cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" HPA076675 Enhanced Supported "Plasma membrane,Centriolar satellite" NA NA 370000 "Cluster 7: Non-specific - Innate immune response" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 47: Leukemia - Hemostasis" "Cluster 47: Platelets - Hemostasis" 28 "Plasma membrane" "Centriolar satellite" "HPA076675: " "unprognostic (7.40e-2)" "unprognostic (6.25e-2)" "unprognostic (3.47e-1)" "unprognostic (9.64e-2)" "unprognostic (9.94e-2)" "unprognostic (2.23e-1)" "unprognostic (8.35e-2)" "unprognostic (2.52e-1)" "unprognostic (3.34e-3)" "unprognostic (1.78e-1)" "potential prognostic favorable (1.82e-9)" "unprognostic (7.18e-2)" "unprognostic (7.43e-2)" "unprognostic (6.94e-2)" "unprognostic (1.55e-1)" "unprognostic (8.79e-2)" "unprognostic (2.64e-2)" "unprognostic (1.96e-1)" "unprognostic (1.93e-1)" "unprognostic (2.18e-3)" "unprognostic (3.47e-2)" "unprognostic (7.24e-3)" "unprognostic (6.33e-2)" "unprognostic (2.40e-2)" "unprognostic (5.65e-2)" "unprognostic (9.04e-2)" "unprognostic (2.58e-1)" "unprognostic (1.51e-1)" "unprognostic (1.85e-2)" "unprognostic (1.41e-1)" "unprognostic (1.98e-1)" MPP2 "DKFZp761D0712, DLG2" ENSG00000108852 "MAGUK p55 scaffold protein 2" Q14168 17 43875357-43909711 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 38.3;Choroid plexus epithelial cells: 50.0;Corticotrophs: 46.4;Early primary spermatocytes: 45.4;Early spermatids: 100.4;Late spermatids: 39.1;Oligodendrocytes: 62.6;Retinal bipolar cells: 107.7;Retinal horizontal cells: 44.1;Retinal pigment epithelial cells: 38.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 13.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal medulla cells, Heart muscle - Cardiomyocytes, Pituitary gland - Corticotropes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026486, HPA073483" Enhanced NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 22: Epididymis - Mixed function" "Cluster 30: White matter - Myelination" "Cluster 27: Breast cancer - Unknown function" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 4 "HPA026486: , HPA073483: " "unprognostic (4.44e-1)" "unprognostic (7.79e-2)" "unprognostic (1.35e-1)" "unprognostic (6.59e-2)" "unprognostic (1.40e-1)" "unprognostic (4.01e-2)" "unprognostic (1.44e-1)" "unprognostic (5.25e-2)" "potential prognostic unfavorable (6.49e-5)" "unprognostic (1.08e-1)" "unprognostic (3.45e-1)" "unprognostic (2.13e-1)" "unprognostic (2.82e-1)" "unprognostic (1.11e-1)" "unprognostic (4.34e-3)" "unprognostic (3.62e-2)" "unprognostic (3.63e-1)" "unprognostic (1.15e-3)" "unprognostic (6.51e-2)" "unprognostic (6.83e-2)" "unprognostic (6.82e-2)" "unprognostic (3.76e-1)" "unprognostic (2.22e-2)" "unprognostic (2.05e-1)" "unprognostic (5.08e-2)" "unprognostic (1.08e-2)" MPP3 DLG3 ENSG00000161647 "MAGUK p55 scaffold protein 3" Q13368 17 43800799-43833170 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 28.2;heart muscle: 14.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 98.7;Cardiomyocytes: 357.9;Choroid plexus epithelial cells: 78.0;Early spermatids: 47.7;Late spermatids: 101.4" "Cell type enhanced" "Detected in all" "upper rhombic lip: 59.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021818, HPA024742" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 25: Non-specific - Transcription" "Cluster 1: Neuronal - Visual perception" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 13 "Nucleoplasm, Cytosol" "HPA021818: , HPA024742: " "unprognostic (2.41e-2)" "unprognostic (5.89e-2)" "unprognostic (2.94e-2)" "unprognostic (2.15e-3)" "unprognostic (3.44e-3)" "unprognostic (3.41e-2)" "unprognostic (1.86e-1)" "unprognostic (6.41e-3)" "unprognostic (7.93e-2)" MPP4 DLG6 ENSG00000082126 "MAGUK p55 scaffold protein 4" Q96JB8 2 201644870-201698694 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 175 "retina: 265.2" "Group enriched" "Detected in some" 37 "Cone photoreceptor cells: 1343.5;Rod photoreceptor cells: 930.4" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 7.8;Sarcoma: 8.8" "Testis - Late spermatids" "Low region specificity" "Detected in single" "Region enhanced" "Detected in many" "cerebellum: 5.0" HPA057393 Supported "Actin filaments,Cytosol" No No "Cluster 42: Retina - Visual perception" "Cluster 35: Non-specific - DNA binding" "Cluster 72: Neuronal - Signal transduction" "Cluster 79: Photoreceptor cells - Phototransduction" 2 Cytosol "Actin filaments" "HPA057393: " "unprognostic (4.54e-1)" "unprognostic (7.56e-3)" MPP7 FLJ32798 ENSG00000150054 "MAGUK p55 scaffold protein 7" Q5T2T1 10 28050993-28334486 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 34.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 381.2;Lymphatic endothelial cells: 424.1;Neutrophil progenitors: 655.5;Neutrophils: 609.7;Renal collecting duct intercalated cells: 408.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal cortex cells, Lung - Alveolar cells type 2, Skeletal muscle - Skeletal myocytes, Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037597, HPA037598" Approved Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 2: Neurons - Nucleosome" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 27 "Cell Junctions" Nucleoplasm "HPA037597: , HPA037598: " "unprognostic (8.65e-2)" "unprognostic (1.79e-1)" "unprognostic (2.48e-1)" "unprognostic (1.45e-1)" "unprognostic (7.48e-2)" "potential prognostic favorable (3.01e-4)" "unprognostic (1.80e-1)" "unprognostic (7.99e-2)" "unprognostic (2.21e-2)" "potential prognostic favorable (7.31e-8)" "unprognostic (4.01e-2)" "unprognostic (1.02e-1)" "unprognostic (1.43e-3)" "unprognostic (4.27e-2)" "unprognostic (3.45e-3)" "unprognostic (1.63e-2)" "unprognostic (6.67e-2)" "unprognostic (2.78e-1)" "unprognostic (1.41e-1)" "unprognostic (3.31e-2)" "unprognostic (9.31e-2)" "unprognostic (2.82e-1)" "unprognostic (2.46e-1)" "unprognostic (5.89e-3)" "unprognostic (7.93e-2)" "unprognostic (2.48e-1)" "unprognostic (6.09e-2)" "unprognostic (4.08e-2)" MPPE1 "Cdc1, PGAP5" ENSG00000154889 "Metallophosphoesterase 1" Q53F39 18 11882622-11908366 "Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, GPI-anchor biosynthesis, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 113.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "eosinophil: 101.8;neutrophil: 297.3" "Lineage enriched" "Detected in all" 7 "granulocytes: 297.3" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012639 Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 72: Kidney - Transmembrane transport" "Cluster 45: Non-specific - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 24: Neutrophils - Innate immunity signal integration" 1 "Nucleoplasm, Golgi apparatus" "HPA012639: " "unprognostic (1.69e-1)" "unprognostic (2.95e-1)" "unprognostic (8.75e-3)" "unprognostic (7.45e-2)" "unprognostic (3.57e-1)" "unprognostic (1.66e-1)" "unprognostic (3.59e-2)" "unprognostic (5.99e-3)" "unprognostic (1.96e-1)" "unprognostic (2.58e-1)" "potential prognostic favorable (2.24e-8)" "unprognostic (5.80e-2)" "potential prognostic favorable (4.47e-5)" "unprognostic (1.28e-1)" "unprognostic (1.12e-2)" "unprognostic (1.39e-1)" "unprognostic (4.26e-2)" "unprognostic (9.50e-2)" "unprognostic (6.33e-2)" "unprognostic (4.95e-2)" "unprognostic (1.81e-1)" "unprognostic (4.75e-3)" "unprognostic (1.99e-1)" "unprognostic (8.97e-2)" "unprognostic (6.81e-2)" "unprognostic (2.19e-2)" "unprognostic (3.56e-1)" "unprognostic (2.41e-1)" "unprognostic (9.56e-2)" "unprognostic (9.41e-2)" "unprognostic (2.80e-1)" MPPED1 "239AB, C22orf1, FAM1A" ENSG00000186732 "Metallophosphoesterase domain containing 1" O15442 22 43411196-43507848 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 21 "brain: 51.7;liver: 22.0" "Cell type enhanced" "Detected in some" "Bergmann glia: 18.0;Brain excitatory neurons: 40.4;Brain inhibitory neurons: 39.6;Gonadotrophs: 63.2;Hepatocytes: 16.6;Peritubular myoid cells: 47.8;Retinal amacrine cells: 15.7" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Liver Hepatocellular Carcinoma (TCGA): 3.3;Lung Squamous Cell Carcinoma (TCGA): 2.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lung cancer: 1.3" "Pituitary gland - Gonadotropes" "Group enriched" "Detected in all" 5 "amygdala: 105.7;basal ganglia: 66.2;cerebral cortex: 163.5;hippocampal formation: 174.5;white matter: 106.3" "Group enriched" "Detected in all" 5 "cerebral cortex: 137.2;hippocampal formation: 120.8" NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 53: Neurons - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" 19 "unprognostic (2.82e-1)" "unprognostic (5.52e-2)" "unprognostic (6.16e-2)" "unprognostic (9.24e-2)" "potential prognostic favorable (2.80e-4)" "unprognostic (1.09e-2)" "unprognostic (1.87e-3)" MPPED2 "239FB, C11orf8, D11S302E, dJ1024C24.1, dJ873F21.1, FAM1B, Hs.46638" ENSG00000066382 "Metallophosphoesterase domain containing 2" Q15777 11 30384493-30586872 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 23.0;thyroid gland: 23.0" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 536.9;Cone photoreceptor cells: 621.0;Kupffer cells: 401.8;Oligodendrocyte progenitor cells: 459.1;Pituitary stem cells: 1422.7;Prostatic glandular cells: 843.4;Prostatic hillock cells: 398.1;Renal collecting duct intercalated cells: 1167.8;Renal collecting duct principal cells: 582.9;Renal connecting tubule cells: 777.8" "Cell type enhanced" "Detected in all" "pericyte: 819.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "MAIT T-cell: 1.8" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Rhabdoid: 8.1" "Pituitary gland - Thyrotropes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062575 Approved Nucleoli,Vesicles,Mitochondria NA NA "Cluster 33: Thyroid gland - Tissue development" "Cluster 24: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 12 Nucleoli "Vesicles, Mitochondria" "HPA062575: " "unprognostic (3.02e-2)" "unprognostic (3.77e-2)" "unprognostic (4.71e-2)" "unprognostic (4.97e-3)" "unprognostic (3.59e-2)" "unprognostic (6.01e-2)" "unprognostic (2.07e-3)" "unprognostic (4.14e-2)" "unprognostic (7.97e-3)" "validated prognostic favorable (1.69e-8)" "validated prognostic favorable (9.59e-4)" "unprognostic (4.89e-3)" "unprognostic (1.08e-1)" "unprognostic (2.71e-2)" "unprognostic (5.55e-2)" "unprognostic (1.17e-1)" "potential prognostic favorable (7.19e-4)" "unprognostic (8.75e-2)" "unprognostic (9.75e-2)" "unprognostic (2.01e-2)" "unprognostic (4.05e-3)" "unprognostic (1.50e-1)" "unprognostic (2.58e-2)" "unprognostic (3.16e-1)" MPRIP "M-RIP, p116Rip, RHOIP3" ENSG00000133030 "Myosin phosphatase Rho interacting protein" Q6WCQ1 17 17042457-17217679 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 490.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "T-reg: 61.0" "Lineage enriched" "Detected in all" 6 "T-cells: 61.0" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022034, HPA022901" Enhanced Supported "Actin filaments,Cytosol" NA NA 7700 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 74: Non-specific - Signal transduction" "Cluster 37: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 51: Secretory epithelial cells - Mixed function" 57 "Actin filaments" Cytosol "HPA022034: , HPA022901: " "unprognostic (4.04e-3)" "unprognostic (2.32e-2)" "unprognostic (1.68e-2)" "unprognostic (1.47e-1)" "unprognostic (2.06e-2)" "unprognostic (2.24e-2)" "unprognostic (7.19e-2)" "unprognostic (9.03e-3)" "unprognostic (6.00e-3)" "unprognostic (4.88e-3)" "unprognostic (2.05e-1)" "potential prognostic favorable (5.56e-5)" "unprognostic (8.84e-2)" "unprognostic (1.04e-1)" "unprognostic (2.46e-2)" "unprognostic (5.77e-2)" "unprognostic (1.76e-3)" "unprognostic (8.83e-3)" "unprognostic (1.67e-1)" "unprognostic (6.21e-2)" "unprognostic (1.07e-1)" "unprognostic (8.46e-2)" "unprognostic (1.42e-3)" "unprognostic (1.18e-1)" "unprognostic (9.13e-2)" "unprognostic (5.95e-2)" "unprognostic (6.60e-2)" "unprognostic (2.22e-1)" "unprognostic (1.89e-1)" "unprognostic (1.29e-1)" "unprognostic (8.16e-2)" MPST "MST, TST2, TUM1" ENSG00000128309 "Mercaptopyruvate sulfurtransferase" P25325 22 37019635-37029821 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 370.6" "Cell type enhanced" "Detected in many" "Colonocytes: 517.0;Enteric stem cells: 312.8;Enteric transient amplifying cells: 379.8;Enterocytes: 1169.7;Esophageal apical cells: 675.2;Esophageal suprabasal cells: 348.4;Hepatocytes: 650.0;Paneth cells: 313.3" "Cell type enhanced" "Detected in many" "Bergmann glia: 37.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001240 Enhanced Approved Mitochondria,Cytosol NA NA 3600000 "Cluster 29: Non-specific - Unknown function" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 11: White matter - Signal transduction" "Cluster 25: Non-specific - Ribosome" "Cluster 1: Enterocytes - Absorption and Digestion" 2 Mitochondria Cytosol "HPA001240: " "unprognostic (1.25e-1)" "unprognostic (1.15e-2)" "unprognostic (4.05e-2)" "unprognostic (9.72e-2)" "unprognostic (2.66e-1)" "unprognostic (8.24e-2)" "validated prognostic favorable (1.54e-4)" "validated prognostic favorable (1.71e-5)" "unprognostic (1.09e-2)" "unprognostic (2.82e-1)" "unprognostic (1.49e-1)" "unprognostic (6.12e-2)" "unprognostic (2.17e-2)" "unprognostic (4.66e-2)" "unprognostic (3.89e-2)" "unprognostic (7.06e-2)" "unprognostic (1.83e-1)" "unprognostic (2.70e-2)" "unprognostic (8.89e-2)" "unprognostic (1.79e-1)" "unprognostic (6.58e-2)" "unprognostic (1.73e-1)" "unprognostic (1.37e-1)" "unprognostic (8.53e-2)" "unprognostic (8.46e-2)" "unprognostic (4.98e-2)" "unprognostic (1.04e-1)" "unprognostic (6.05e-2)" "unprognostic (8.03e-2)" "unprognostic (9.40e-2)" "unprognostic (3.61e-3)" MPV17 SYM1 ENSG00000115204 "Mitochondrial inner membrane protein MPV17" P39210 2 27309492-27325680 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 200.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 27: Non-specific - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 97: Non-specific - Cellular respiration" 1 "unprognostic (2.23e-1)" "unprognostic (4.24e-2)" "unprognostic (3.14e-1)" "unprognostic (8.95e-2)" "unprognostic (1.42e-2)" "unprognostic (1.35e-1)" "unprognostic (2.65e-2)" "unprognostic (1.67e-1)" "unprognostic (1.26e-1)" "unprognostic (9.74e-3)" "potential prognostic favorable (4.34e-6)" "unprognostic (1.30e-1)" "unprognostic (4.91e-2)" "validated prognostic unfavorable (3.01e-8)" "validated prognostic unfavorable (1.86e-4)" "unprognostic (1.19e-2)" "unprognostic (2.06e-1)" "unprognostic (3.16e-1)" "unprognostic (6.90e-3)" "unprognostic (2.17e-1)" "unprognostic (2.14e-1)" "unprognostic (5.07e-2)" "unprognostic (1.85e-3)" "unprognostic (1.51e-1)" "unprognostic (1.98e-1)" "unprognostic (4.80e-3)" "unprognostic (1.39e-1)" "unprognostic (3.07e-2)" "unprognostic (4.59e-2)" "potential prognostic favorable (2.46e-4)" "unprognostic (2.32e-1)" MPV17L "FLJ39599, MLPH1, MLPH2, MPV17L1" ENSG00000156968 "MPV17 mitochondrial inner membrane protein like" Q2QL34 16 15395754-15413271 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 11.6" "Cell type enhanced" "Detected in some" "Breast lactating cells: 1.5;Conjunctival goblet cells: 1.9;Endometrial secretory cells: 1.3;Innate lymphoid cells: 1.7;Late primary spermatocytes: 2.9;Megakaryocyte-Erythroid progenitors: 1.1;Thymic myoid cells: 2.7" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041180 Approved Supported Vesicles NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 70: Non-specific - Protein processing" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 49: HMC-1 - Innate immune response" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" Vesicles "HPA041180: " "unprognostic (1.79e-1)" "unprognostic (1.06e-1)" "unprognostic (4.09e-2)" "unprognostic (2.41e-1)" "unprognostic (1.00e-2)" "unprognostic (1.54e-1)" "unprognostic (1.56e-2)" "potential prognostic unfavorable (2.70e-5)" "unprognostic (3.59e-2)" "unprognostic (5.39e-2)" "validated prognostic favorable (6.37e-5)" "validated prognostic favorable (2.96e-6)" "unprognostic (2.63e-1)" "unprognostic (2.25e-1)" "unprognostic (1.84e-1)" "unprognostic (3.37e-3)" "unprognostic (1.70e-1)" "unprognostic (3.10e-1)" "unprognostic (1.86e-2)" "unprognostic (3.99e-2)" "unprognostic (3.22e-3)" "unprognostic (2.41e-1)" "unprognostic (4.09e-2)" "unprognostic (6.95e-2)" "unprognostic (1.10e-1)" "unprognostic (3.51e-2)" "unprognostic (1.16e-1)" "unprognostic (2.82e-1)" "unprognostic (1.93e-1)" "unprognostic (1.27e-1)" "unprognostic (2.16e-1)" MPV17L2 "FKSG24, MGC12972" ENSG00000254858 "MPV17 mitochondrial inner membrane protein like 2" Q567V2 19 18193218-18196948 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 44.3;Epididymal principal cells: 69.2;Extravillous trophoblasts: 34.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043111 Uncertain NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 27: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" "HPA043111: " "unprognostic (1.07e-1)" "unprognostic (1.36e-1)" "unprognostic (5.98e-2)" "unprognostic (1.86e-2)" "unprognostic (1.68e-1)" "unprognostic (1.12e-1)" "unprognostic (2.73e-1)" "unprognostic (2.53e-1)" "unprognostic (1.88e-1)" "unprognostic (1.13e-1)" "unprognostic (3.57e-3)" "unprognostic (5.02e-3)" "unprognostic (2.44e-2)" "unprognostic (1.20e-2)" "unprognostic (1.67e-2)" "unprognostic (1.12e-1)" "unprognostic (6.00e-2)" "unprognostic (3.84e-2)" "unprognostic (6.42e-3)" "unprognostic (1.50e-1)" "unprognostic (1.41e-2)" "unprognostic (5.53e-2)" "unprognostic (4.49e-2)" "unprognostic (2.73e-1)" "unprognostic (1.07e-1)" "unprognostic (1.94e-1)" "unprognostic (1.99e-1)" "unprognostic (2.93e-1)" "unprognostic (6.73e-2)" "unprognostic (1.90e-1)" "unprognostic (8.03e-2)" MPZ "CMT1, CMT1B, CMT2I, CMT2J, HMSNIB, P0" ENSG00000158887 "Myelin protein zero" P25189 1 161304735-161309968 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Charcot-Marie-Tooth disease, Deafness, Dejerine-Sottas syndrome, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 31.1" "Cell type enriched" "Detected in many" 12 "Schwann cells: 787.2" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in many" 10 "Skin Cutaneous Melanoma (TCGA): 111.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Brain cancer: 17.5;skin cancer: 61.4" "Colon - Enteric glia cells, Liver - Vascular endothelial cells" "Group enriched" "Detected in some" 4 "olfactory bulb: 2.9;pons and medulla: 1.3" "Region enriched" "Detected in many" 10 "spinal cord: 2820.7" HPA068925 Enhanced NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 74: Non-specific - Signal transduction" "Cluster 7: Non-specific - Ribosome" "Cluster 69: Skin cancer - ECM organization" "Cluster 61: Schwann cells & Melanocytes - Mixed function" 1 "HPA068925: " "unprognostic (1.00e-1)" "unprognostic (3.52e-1)" "unprognostic (3.40e-2)" "unprognostic (2.78e-2)" "unprognostic (5.79e-2)" "unprognostic (1.12e-2)" "unprognostic (1.05e-1)" "unprognostic (5.44e-2)" "unprognostic (5.04e-3)" "unprognostic (1.91e-1)" "potential prognostic unfavorable (4.45e-4)" "unprognostic (4.54e-2)" "unprognostic (9.76e-2)" "unprognostic (2.44e-1)" "unprognostic (4.05e-3)" "unprognostic (3.85e-2)" "unprognostic (2.22e-2)" "unprognostic (4.86e-2)" "unprognostic (1.83e-1)" "unprognostic (3.61e-2)" "unprognostic (1.77e-1)" MPZL1 "FLJ21047, PZR" ENSG00000197965 "Myelin protein zero like 1" O95297 1 167721192-167791919 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 337.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 184.9" "Lineage enriched" "Detected in all" 4 "granulocytes: 184.9" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Adrenal gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026966, HPA063538" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 75: Ovary - Mixed function" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 45: Non-specific - Nuclear processes" "Cluster 24: Neutrophils - Innate immunity signal integration" 9 "Vesicles, Plasma membrane" "HPA026966: , HPA063538: " "unprognostic (3.36e-1)" "unprognostic (1.73e-1)" "unprognostic (7.49e-3)" "potential prognostic unfavorable (3.51e-5)" "unprognostic (5.92e-2)" "unprognostic (2.29e-1)" "unprognostic (1.69e-2)" "unprognostic (3.54e-1)" "unprognostic (2.07e-1)" "unprognostic (4.77e-3)" "unprognostic (3.62e-3)" "potential prognostic unfavorable (3.30e-6)" "unprognostic (8.00e-2)" "potential prognostic unfavorable (7.77e-5)" "unprognostic (5.46e-3)" "unprognostic (2.49e-3)" "unprognostic (3.29e-3)" "unprognostic (7.58e-3)" "unprognostic (3.31e-2)" "unprognostic (4.13e-1)" "unprognostic (7.45e-2)" "unprognostic (1.62e-2)" "unprognostic (3.48e-2)" "unprognostic (3.68e-1)" "unprognostic (1.32e-1)" "unprognostic (1.07e-1)" "unprognostic (2.04e-2)" "unprognostic (2.39e-1)" "unprognostic (4.77e-1)" "unprognostic (2.58e-3)" "unprognostic (2.46e-1)" MPZL2 "EVA, EVA1" ENSG00000149573 "Myelin protein zero like 2" O60487 11 118253416-118264536 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 208.1;urinary bladder: 145.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 313.2;Epididymal basal cells: 279.9;Esophageal apical cells: 1437.9;Esophageal basal cells: 351.1;Esophageal suprabasal cells: 942.7;Ocular epithelial cells: 418.2;Suprabasal keratinocytes: 532.0;Urothelial cells: 245.0" "Group enriched" "Detected in some" 10 "endothelial cell: 29.6;fibroblast: 9.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 11.7;intermediate monocyte: 9.2;myeloid DC: 17.0;neutrophil: 13.2" "Group enriched" "Detected in many" 10 "dendritic cells: 17.0;granulocytes: 13.2;monocytes: 11.7" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Lung - Alveolar cells type 2, Skeletal muscle - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 5 "spinal cord: 51.3" HPA060740 Approved Approved "Cell Junctions" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 5 "Cell Junctions" "HPA060740: " "unprognostic (6.40e-3)" "unprognostic (1.13e-2)" "unprognostic (1.09e-2)" "unprognostic (4.43e-3)" "unprognostic (2.61e-1)" "potential prognostic favorable (5.32e-4)" "unprognostic (1.02e-3)" "potential prognostic unfavorable (9.42e-4)" "unprognostic (9.19e-2)" "unprognostic (3.36e-1)" "validated prognostic favorable (3.97e-10)" "validated prognostic favorable (5.16e-7)" "unprognostic (2.26e-1)" "unprognostic (3.42e-3)" "unprognostic (2.04e-2)" "unprognostic (1.52e-1)" "unprognostic (2.82e-1)" "unprognostic (1.86e-1)" "unprognostic (1.37e-1)" "unprognostic (2.31e-1)" "unprognostic (6.12e-2)" "potential prognostic unfavorable (9.41e-5)" "unprognostic (2.61e-2)" "unprognostic (1.71e-1)" "unprognostic (5.57e-2)" "unprognostic (7.10e-2)" "unprognostic (2.43e-2)" "unprognostic (3.01e-2)" "unprognostic (1.53e-1)" "unprognostic (1.87e-3)" "unprognostic (6.59e-2)" MPZL3 ENSG00000160588 "Myelin protein zero like 3" Q6UWV2 11 118226690-118252365 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 32.0;skin 1: 28.9" "Cell type enhanced" "Detected in many" "Enterocytes: 215.1;Esophageal apical cells: 693.9;Innate lymphoid cells: 201.9;Ocular epithelial cells: 206.1;T-cells: 231.4" "Cell type enriched" "Detected in many" 4 "leukocyte: 81.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "basophil: 44.4;eosinophil: 99.4;MAIT T-cell: 28.9;neutrophil: 87.8" "Group enriched" "Detected in all" 8 "granulocytes: 99.4;T-cells: 28.9" "Low cancer specificity" "Detected in many" "Adipose visceral - T-cells, Skeletal muscle - Endothelial cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029116 Approved "Golgi apparatus" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 15: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 9: T-cells - Adaptive immunity: Regulation" 3 "Golgi apparatus" "HPA029116: " "unprognostic (3.48e-2)" "unprognostic (1.94e-2)" "unprognostic (1.25e-1)" "unprognostic (4.02e-2)" "unprognostic (2.03e-1)" "unprognostic (1.52e-1)" "unprognostic (5.38e-3)" "unprognostic (2.01e-1)" "unprognostic (3.42e-1)" "unprognostic (9.42e-3)" "potential prognostic favorable (6.09e-4)" "unprognostic (2.31e-2)" "unprognostic (2.40e-3)" "unprognostic (9.27e-2)" "unprognostic (1.32e-1)" "unprognostic (1.01e-2)" "potential prognostic unfavorable (2.05e-5)" "unprognostic (3.71e-1)" "unprognostic (5.59e-2)" "unprognostic (3.53e-2)" "unprognostic (2.58e-3)" "potential prognostic unfavorable (5.15e-5)" "unprognostic (4.44e-2)" "unprognostic (3.85e-1)" "unprognostic (1.25e-2)" "unprognostic (1.01e-2)" "unprognostic (2.40e-1)" "unprognostic (2.73e-1)" "unprognostic (1.45e-2)" "unprognostic (3.06e-1)" MR1 HLALS ENSG00000153029 "Major histocompatibility complex, class I-related" Q95460 1 181033374-181061938 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 79.2" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 50.4;leukocyte: 48.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells, Kidney - Fibroblasts, Lung - Macrophages, Skin - Langerhans cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048304 Supported "Plasma membrane" "Intracellular and membrane" Immunity NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 1 "Plasma membrane" "HPA048304: " "unprognostic (2.35e-1)" "unprognostic (3.46e-1)" "unprognostic (1.75e-1)" "unprognostic (6.26e-3)" "unprognostic (2.36e-1)" "unprognostic (1.43e-1)" "unprognostic (1.56e-2)" "unprognostic (1.52e-2)" "unprognostic (1.35e-2)" "unprognostic (4.72e-3)" "unprognostic (1.84e-2)" "unprognostic (2.91e-1)" "unprognostic (2.26e-1)" "unprognostic (6.11e-2)" "unprognostic (2.55e-1)" "unprognostic (4.22e-2)" "unprognostic (3.76e-1)" "unprognostic (2.68e-1)" "unprognostic (3.29e-3)" "unprognostic (3.15e-1)" "unprognostic (1.62e-3)" "unprognostic (5.02e-2)" "unprognostic (7.80e-2)" "unprognostic (7.06e-2)" "unprognostic (1.15e-2)" "unprognostic (1.01e-1)" "unprognostic (1.38e-1)" "unprognostic (6.73e-3)" "unprognostic (4.59e-2)" "unprognostic (1.59e-1)" "unprognostic (2.35e-1)" MRAP "B27, C21orf61, FALP" ENSG00000170262 "Melanocortin 2 receptor accessory protein" Q8TCY5 21 32291813-32314784 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "adipose tissue: 73.5;adrenal gland: 155.2;breast: 44.5" "Cell type enhanced" "Detected in many" "Adipocytes: 29.3;Adrenal cortex cells: 38.4;Cardiomyocytes: 30.0;Early spermatids: 17.2;Ependymal cells: 12.8;Epicardial cells: 86.4;Late primary spermatocytes: 18.0;Retinal horizontal cells: 34.1" "Group enriched" "Detected in many" 4 "ependymal cell: 19.9;oligodendrocyte: 5.3" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 8.1" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "NK-cell: 1.9" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Minor Salivary Gland - Adipocytes (Minor salivary gland), Skin - Adipocytes (Skin)" "Not detected" "Not detected" "Not detected" "Not detected" "HPA011024, HPA011093" Uncertain Supported "Endoplasmic reticulum,Vesicles" NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 8: Immune cells - Immune response" "Cluster 18: Liver cancer - Metabolism" "Cluster 89: Adipocytes - Lipid metabolism" 5 "Endoplasmic reticulum" Vesicles "HPA011024: , HPA011093: " "unprognostic (1.22e-1)" "unprognostic (4.15e-2)" "unprognostic (2.44e-1)" "unprognostic (3.01e-1)" "unprognostic (2.74e-2)" "potential prognostic unfavorable (9.77e-4)" "unprognostic (2.58e-3)" "unprognostic (1.13e-1)" "unprognostic (3.89e-1)" "unprognostic (2.40e-2)" "unprognostic (3.61e-2)" MRAP2 "bA51G5.2, C6orf117" ENSG00000135324 "Melanocortin 2 receptor accessory protein 2" Q96G30 6 84033772-84090881 "Disease related genes, Human disease related genes, Predicted membrane proteins" Obesity "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "blood vessel: 97.2" "Cell type enhanced" "Detected in many" "Bergmann glia: 41.5;Brain excitatory neurons: 35.1;Brain inhibitory neurons: 35.8;Choroid plexus epithelial cells: 34.3;Ependymal cells: 33.0;Fallopian tube ciliated cells: 26.5;Foveolar cells: 33.3;Gonadotrophs: 43.8;Myosatellite cells: 48.4;Other brain neurons: 46.0;Pancreatic islet cells: 52.0;Pituitary stem cells: 26.8" "Cell type enhanced" "Detected in many" "eccentric medium spiny neuron: 137.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 5.4" "Adipose visceral - Smooth muscle cells, Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 12 "unprognostic (1.22e-2)" "unprognostic (1.67e-3)" "unprognostic (3.04e-1)" "unprognostic (1.36e-1)" "unprognostic (2.02e-2)" "unprognostic (1.93e-1)" "unprognostic (3.41e-2)" "unprognostic (5.28e-2)" "unprognostic (4.69e-1)" "unprognostic (3.02e-2)" "unprognostic (2.24e-2)" "unprognostic (9.21e-2)" "unprognostic (2.68e-1)" "unprognostic (1.09e-1)" "unprognostic (3.22e-3)" "unprognostic (4.58e-3)" "unprognostic (3.93e-3)" "unprognostic (8.93e-2)" "unprognostic (2.40e-2)" "unprognostic (3.00e-3)" "unprognostic (3.74e-1)" "unprognostic (2.06e-2)" "unprognostic (3.53e-3)" "unprognostic (1.99e-1)" "unprognostic (9.00e-2)" "unprognostic (7.15e-2)" "unprognostic (1.18e-1)" MRAS "M-RAs, R-RAS3, RRAS3" ENSG00000158186 "Muscle RAS oncogene homolog" O14807 3 138347648-138405534 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 111.6;heart muscle: 113.4" "Cell type enhanced" "Detected in many" "Adipocytes: 149.0;Adrenal cortex cells: 88.4;Astrocytes: 131.7;Bergmann glia: 86.9;Cardiomyocytes: 126.9;Gonadotrophs: 82.1;Late spermatids: 103.3" "Cell type enhanced" "Detected in all" "astrocyte: 198.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "non-classical monocyte: 25.3" "Lineage enriched" "Detected in many" 9 "monocytes: 25.3" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042728 Approved Approved Vesicles,Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 19: Astrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 89: Adipocytes - Lipid metabolism" 7 Cytosol Vesicles "HPA042728: " "unprognostic (5.24e-3)" "unprognostic (7.18e-2)" "unprognostic (8.80e-2)" "unprognostic (3.13e-2)" "unprognostic (5.16e-3)" "unprognostic (8.41e-2)" "unprognostic (2.36e-1)" "unprognostic (2.68e-1)" "unprognostic (4.03e-1)" "unprognostic (3.94e-2)" "unprognostic (8.61e-3)" "unprognostic (1.94e-1)" "unprognostic (1.60e-2)" "unprognostic (2.23e-1)" "unprognostic (4.41e-3)" "unprognostic (2.15e-2)" "unprognostic (1.92e-1)" "unprognostic (9.26e-2)" "unprognostic (2.51e-2)" "unprognostic (1.56e-1)" "unprognostic (7.88e-3)" "unprognostic (2.35e-1)" "unprognostic (2.48e-1)" "unprognostic (9.43e-2)" "unprognostic (4.01e-2)" "unprognostic (2.74e-2)" "unprognostic (1.24e-1)" "unprognostic (8.47e-3)" "unprognostic (7.38e-2)" "unprognostic (1.77e-1)" "unprognostic (8.30e-2)" MRC1 "bA541I19.1, CD206, CLEC13D, CLEC13DL, MRC1L1" ENSG00000260314 "Mannose receptor C-type 1" P22897 10 17809348-17911164 "CD markers, FDA approved drug targets, Plasma proteins, Predicted membrane proteins" "Endocytosis, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 115.2" "Cell type enhanced" "Detected in many" "Breast lactating cells: 1705.9;cDC: 481.2;Hofbauer cells: 549.3;Kupffer cells: 996.2;Lymphatic endothelial cells: 407.6;Macrophages: 1040.9;monocytes: 334.8" "Cell type enriched" "Detected in many" 17 "central nervous system macrophage: 199.8" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 24.3" "Region enhanced" "Detected in all" "choroid plexus: 20.4" "Immune cell enriched" "Detected in single" 16 "myeloid DC: 4.8" "Lineage enriched" "Detected in single" 16 "dendritic cells: 4.8" "Cancer enriched" "Detected in some" 7 "Rhabdoid: 8.4" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Lung - Macrophages, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004114, HPA045134, CAB068203" Enhanced NA NA 130000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 13: Lung - Secretion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 1 "CAB068203: , HPA004114: , HPA045134: " "unprognostic (8.75e-2)" "unprognostic (8.57e-2)" "unprognostic (5.99e-2)" "unprognostic (3.43e-1)" "unprognostic (2.96e-2)" "unprognostic (7.92e-2)" "unprognostic (1.65e-2)" "unprognostic (3.16e-1)" "unprognostic (7.44e-2)" "potential prognostic favorable (3.42e-4)" "unprognostic (1.24e-1)" "unprognostic (8.90e-2)" "unprognostic (2.10e-2)" "unprognostic (8.99e-2)" "potential prognostic favorable (4.36e-4)" "unprognostic (4.42e-2)" "unprognostic (6.89e-2)" "unprognostic (1.90e-1)" "unprognostic (7.74e-3)" "unprognostic (8.51e-2)" "unprognostic (3.03e-1)" "unprognostic (9.27e-3)" "unprognostic (1.01e-1)" "unprognostic (5.62e-3)" "unprognostic (2.72e-2)" "unprognostic (3.94e-2)" "unprognostic (3.98e-2)" MRC2 "CD280, CLEC13E, ENDO180, KIAA0709" ENSG00000011028 "Mannose receptor C type 2" Q9UBG0 17 62627670-62693597 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 87.8;Early spermatids: 166.3;Endometrial stromal cells: 100.4;Ependymal cells: 93.0;Fibro-adipogenic progenitors: 266.5;Fibroblasts: 163.2;Late spermatids: 200.7;Leydig cells: 128.7;Microglia: 154.2;Peritubular myoid cells: 166.8;Pituitary stem cells: 86.5" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 192.1;fibroblast: 249.1;pericyte: 222.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 132.9" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Adrenal gland - Fibroblasts, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041991 Enhanced NA NA 24000000 "Cluster 75: Ovary - Mixed function" "Cluster 8: Immune cells - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 7 "HPA041991: " "unprognostic (2.87e-2)" "unprognostic (2.11e-1)" "unprognostic (3.23e-1)" "unprognostic (4.46e-2)" "unprognostic (3.30e-2)" "unprognostic (4.06e-2)" "unprognostic (6.79e-2)" "unprognostic (1.08e-3)" "unprognostic (7.00e-2)" "unprognostic (3.46e-2)" "unprognostic (2.47e-3)" "unprognostic (1.17e-1)" "unprognostic (1.06e-1)" "unprognostic (5.88e-2)" "unprognostic (1.56e-2)" "unprognostic (4.75e-2)" "unprognostic (1.79e-1)" "unprognostic (3.03e-2)" "unprognostic (5.42e-1)" "potential prognostic unfavorable (8.76e-4)" "unprognostic (2.85e-2)" "unprognostic (1.80e-2)" "unprognostic (1.71e-1)" "unprognostic (1.24e-2)" "unprognostic (2.24e-1)" "unprognostic (4.86e-3)" "unprognostic (2.95e-2)" "unprognostic (2.19e-2)" "unprognostic (1.90e-1)" "unprognostic (7.36e-2)" "unprognostic (3.21e-1)" MRE11 "ATLD, MRE11A" ENSG00000020922 "MRE11 homolog, double strand break repair nuclease" P49959 11 94415570-94493885 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction, Meiosis" "Endonuclease, Exonuclease, Hydrolase, Nuclease" "Cancer-related genes, Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002691, CAB004081" Supported Enhanced Nucleoplasm NA NA 4000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 54: Non-specific - Ribosome" "Cluster 46: Brainstem - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 83 Nucleoplasm "CAB004081: , HPA002691: " "unprognostic (1.13e-1)" "unprognostic (1.78e-3)" "unprognostic (8.41e-2)" "unprognostic (1.87e-1)" "unprognostic (1.46e-1)" "unprognostic (5.06e-2)" "unprognostic (1.08e-1)" "unprognostic (1.74e-1)" "unprognostic (1.95e-2)" "unprognostic (4.35e-3)" "unprognostic (2.48e-2)" "unprognostic (2.47e-2)" "potential prognostic unfavorable (3.17e-4)" "potential prognostic unfavorable (5.64e-4)" "unprognostic (1.63e-2)" "unprognostic (1.40e-1)" "unprognostic (3.01e-1)" "unprognostic (3.58e-2)" "unprognostic (2.13e-2)" "unprognostic (4.71e-3)" "unprognostic (9.70e-3)" "unprognostic (2.49e-3)" "potential prognostic favorable (4.59e-5)" "unprognostic (7.60e-3)" "unprognostic (6.94e-3)" "unprognostic (3.08e-1)" "unprognostic (1.65e-1)" "unprognostic (2.15e-2)" "unprognostic (1.43e-1)" MREG "DSU, FLJ10116, WDT2" ENSG00000118242 Melanoregulin Q8N565 2 215942584-216034096 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 43.4" "Cell type enhanced" "Detected in many" "Adipocytes: 140.6;Cone photoreceptor cells: 140.8;Endometrial glandular cells: 182.9;Endometrial secretory cells: 102.1;Esophageal apical cells: 292.6;Esophageal suprabasal cells: 124.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Liver - Hepatocytes, Skeletal muscle - Fibroblasts, Skin - Hair cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068583 Approved Vesicles NA NA "Cluster 1: T-cells - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 35: Non-specific - DNA binding" "Cluster 11: Neuronal - Sensory perception" "Cluster 51: Secretory epithelial cells - Mixed function" 2 Vesicles "HPA068583: " "unprognostic (3.18e-3)" "unprognostic (1.22e-1)" "unprognostic (2.39e-1)" "unprognostic (2.55e-2)" "unprognostic (1.76e-1)" "unprognostic (2.38e-2)" "unprognostic (2.61e-1)" "unprognostic (1.98e-1)" "unprognostic (1.58e-2)" "unprognostic (1.19e-1)" "unprognostic (5.53e-2)" "unprognostic (3.41e-3)" "unprognostic (3.43e-2)" "unprognostic (3.06e-1)" "unprognostic (3.80e-3)" "unprognostic (2.45e-1)" "unprognostic (5.98e-3)" "unprognostic (1.70e-1)" "unprognostic (2.06e-1)" "unprognostic (2.55e-1)" "unprognostic (2.42e-1)" "unprognostic (6.73e-3)" "unprognostic (3.32e-2)" "unprognostic (1.59e-2)" "unprognostic (1.79e-1)" "unprognostic (2.85e-2)" "unprognostic (8.73e-2)" "unprognostic (1.64e-2)" "unprognostic (4.25e-1)" "unprognostic (2.65e-3)" "unprognostic (1.44e-2)" MRFAP1 "PAM14, PGR1" ENSG00000179010 "Morf4 family associated protein 1" Q9Y605 4 6640091-6642729 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 657.3;Migrating cytotrophoblasts: 525.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "CAB042447, HPA056367" Approved Supported Nucleoplasm No No "Cluster 35: Neutrophils - Protein binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 64 Nucleoplasm "CAB042447: , HPA056367: " "unprognostic (6.97e-3)" "unprognostic (9.76e-2)" "unprognostic (1.55e-1)" "unprognostic (1.84e-2)" "unprognostic (4.79e-2)" "unprognostic (1.35e-1)" "unprognostic (1.01e-1)" "unprognostic (1.36e-1)" "unprognostic (2.08e-1)" "unprognostic (2.65e-3)" "validated prognostic favorable (1.48e-6)" "validated prognostic favorable (1.78e-4)" "unprognostic (1.22e-2)" "potential prognostic unfavorable (1.49e-4)" "unprognostic (4.93e-3)" "validated prognostic unfavorable (1.52e-4)" "validated prognostic unfavorable (2.42e-4)" "unprognostic (5.07e-3)" "unprognostic (8.92e-2)" "unprognostic (3.47e-1)" "unprognostic (3.70e-1)" "unprognostic (4.12e-2)" "unprognostic (3.77e-1)" "unprognostic (1.32e-2)" "unprognostic (1.84e-1)" "unprognostic (1.28e-1)" "unprognostic (5.26e-2)" "unprognostic (6.05e-2)" "unprognostic (3.76e-1)" "unprognostic (1.40e-1)" "potential prognostic favorable (5.48e-4)" MRFAP1L1 MGC9651 ENSG00000178988 "Morf4 family associated protein 1 like 1" Q96HT8 4 6707701-6709865 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 90.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 17: Non-specific - RNA processing" 65 "unprognostic (8.62e-2)" "unprognostic (3.06e-1)" "unprognostic (7.90e-3)" "unprognostic (4.54e-2)" "unprognostic (1.43e-1)" "unprognostic (2.99e-2)" "unprognostic (1.40e-1)" "unprognostic (3.98e-3)" "unprognostic (9.88e-2)" "unprognostic (1.81e-3)" "validated prognostic favorable (1.45e-7)" "validated prognostic favorable (5.14e-5)" "unprognostic (4.15e-3)" "unprognostic (2.55e-3)" "unprognostic (6.46e-2)" "unprognostic (3.76e-3)" "unprognostic (1.01e-2)" "unprognostic (1.37e-1)" "unprognostic (1.87e-1)" "unprognostic (5.16e-2)" "unprognostic (1.38e-1)" "unprognostic (2.81e-1)" "unprognostic (3.19e-1)" "unprognostic (6.97e-2)" "unprognostic (2.52e-1)" "unprognostic (2.27e-1)" "unprognostic (5.93e-2)" "unprognostic (1.60e-1)" "unprognostic (2.84e-1)" "unprognostic (9.88e-2)" "unprognostic (2.69e-2)" MRGBP "C20orf20, Eaf7, FLJ10914, MRG15BP" ENSG00000101189 "MRG domain binding protein" Q9NV56 20 62796473-62801729 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Growth regulation, Transcription, Transcription regulation" "Activator, Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 46.0" "Group enriched" "Detected in many" 4 "Late primary spermatocytes: 194.8;Late spermatids: 708.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Pancreas - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017012 Enhanced Supported Nucleoplasm NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 67: Testis - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 63 Nucleoplasm "HPA017012: " "unprognostic (2.69e-1)" "unprognostic (3.11e-2)" "unprognostic (3.13e-2)" "unprognostic (1.05e-1)" "unprognostic (1.18e-1)" "unprognostic (5.62e-2)" "unprognostic (3.06e-1)" "unprognostic (1.80e-2)" "potential prognostic unfavorable (4.75e-4)" "potential prognostic unfavorable (2.54e-4)" "unprognostic (2.16e-3)" "unprognostic (2.68e-3)" "potential prognostic unfavorable (2.34e-7)" "unprognostic (1.37e-2)" "unprognostic (8.94e-3)" "unprognostic (4.65e-2)" "unprognostic (8.34e-2)" "unprognostic (2.86e-2)" "unprognostic (2.58e-1)" "unprognostic (1.20e-2)" "unprognostic (1.13e-3)" "unprognostic (2.28e-1)" "unprognostic (1.17e-1)" "unprognostic (9.78e-3)" "unprognostic (2.30e-1)" "unprognostic (9.00e-2)" "unprognostic (1.64e-1)" "unprognostic (2.60e-2)" "unprognostic (2.39e-2)" MRGPRD mrgD ENSG00000172938 "MAS related GPR family member D" Q8TDS7 11 68980021-68980986 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA031346 Uncertain NA NA "Cluster 15: Non-specific - Transcription" "Cluster 59: Leukemia - T-cell receptor" "HPA031346: " MRGPRE "GPR167, mrgE" ENSG00000184350 "MAS related GPR family member E" Q86SM8 11 3225030-3232417 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 1.4;cervix: 1.4" "Cell type enhanced" "Detected in single" "Pancreatic islet cells: 2.2" "Cell type enhanced" "Detected in some" "lower rhombic lip: 9.8;mammillary body: 8.1" "Group enriched" "Detected in some" 4 "Kidney Renal Papillary Cell Carcinoma (TCGA): 1.3;Thyroid Carcinoma (TCGA): 2.8" "Region enhanced" "Detected in many" "pons: 58.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adrenal gland - Adrenal medulla cells" "Low region specificity" "Detected in all" HPA046556 Uncertain NA NA "Cluster 65: Brain - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" "HPA046556: " "unprognostic (3.17e-1)" "unprognostic (8.04e-2)" MRGPRF "GPR140, GPR168, MGC21621, mrgF" ENSG00000172935 "MAS related GPR family member F" Q96AM1 11 69004395-69013382 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 169.7;intestine: 162.2" "Cell type enhanced" "Detected in some" "Decidual stromal cells: 136.3;Fibroblasts: 45.8;Hepatic stellate cells: 64.5;Leydig cells: 42.0;Ovarian stromal cells: 29.0;Pericytes: 81.4;Peritubular myoid cells: 101.6;Podocytes: 56.5;Smooth muscle cells: 157.5;Vascular smooth muscle cells: 128.2" "Group enriched" "Detected in some" 5 "fibroblast: 26.4;vascular associated smooth muscle cell: 75.5" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 21.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 7.4" "Breast - Endothelial cells, Colon - Smooth muscle cells, Prostate - Smooth muscle cells, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Thyroid gland - Smooth muscle cells" "Region enriched" "Detected in many" 5 "cerebellum: 14.8" "Region enhanced" "Detected in many" "spinal cord: 6.4" HPA028811 Approved Approved "Nucleoplasm,Nuclear membrane,Vesicles,Plasma membrane,Primary cilium transition zone" NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 35: Non-specific - DNA binding" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" "Vesicles, Plasma membrane" "Nucleoplasm, Nuclear membrane, Primary cilium transition zone" "HPA028811: " "unprognostic (2.06e-2)" "unprognostic (2.68e-2)" "unprognostic (6.83e-2)" "unprognostic (3.06e-2)" "unprognostic (8.22e-2)" "unprognostic (1.04e-1)" "unprognostic (3.68e-2)" "unprognostic (8.10e-2)" "unprognostic (8.21e-3)" "unprognostic (1.65e-1)" "unprognostic (1.99e-1)" "unprognostic (1.86e-1)" "unprognostic (2.96e-3)" "unprognostic (2.41e-1)" "potential prognostic favorable (5.99e-4)" "unprognostic (1.57e-1)" "unprognostic (3.63e-1)" "unprognostic (2.80e-2)" "unprognostic (9.05e-2)" "unprognostic (7.16e-2)" "unprognostic (1.13e-2)" "unprognostic (2.78e-1)" "unprognostic (8.17e-2)" "unprognostic (7.65e-2)" "unprognostic (7.11e-3)" "unprognostic (3.24e-2)" "unprognostic (1.71e-1)" "unprognostic (1.54e-2)" "unprognostic (9.94e-2)" "unprognostic (1.47e-2)" "unprognostic (2.48e-1)" MRGPRG "GPR169, mrgG" ENSG00000182170 "MAS related GPR family member G" Q86SM5 11 3217944-3218813 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 21 "breast cancer: 2.1" "Testis - Early spermatids" "Not detected" "Not detected" HPA058909 Uncertain NA NA "Cluster 70: DU4475 - Unknown function" "HPA058909: " MRGPRX1 MRGX1 ENSG00000170255 "MAS related GPR family member X1" Q96LB2 11 18933499-18939414 "G-protein coupled receptors, Predicted membrane proteins" "Acute phase" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "Extravillous trophoblasts: 1.9;Migrating cytotrophoblasts: 2.2;Syncytiotrophoblasts: 6.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 15 "Rhabdoid: 39.4" NA NA "Cluster 3: Rhabdoid - Membrane components" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." MRGPRX2 MRGX2 ENSG00000183695 "MAS related GPR family member X2" Q96LB1 11 19054455-19060717 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 6 "Mast cells: 13.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Mast cells, Colon - Mast cells, Skin - Mast cells" HPA055220 Approved NA NA "Cluster 51: Myeloma - Immunoglobulins" "Cluster 58: Mast cells - Allergic inflammatory responses" "HPA055220: " MRGPRX3 MRGX3 ENSG00000179826 "MAS related GPR family member X3" Q96LB0 11 18120955-18138488 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "salivary gland: 2.5" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 2.6;Differentiating spermatogonia: 2.0;Early primary spermatocytes: 3.6;Esophageal apical cells: 2.5;Esophageal basal cells: 3.5;Esophageal suprabasal cells: 2.6;Fibro-adipogenic progenitors: 1.2;Foveolar cells: 1.2;Salivary myoepithelial cells: 5.8;Smooth muscle cells: 2.6;Undifferentiated spermatogonia: 1.7" "Cell type enhanced" "Detected in single" "lower rhombic lip: 1.0" "Cancer enhanced" "Detected in some" "Skin Cutaneous Melanoma (TCGA): 4.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "skin cancer: 11.9" NA NA "Cluster 82: Salivary gland - Secretion" "Cluster 48: Non-specific - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 85: Squamous epithelial cells - Keratinization" 1 "unprognostic (8.68e-2)" "unprognostic (5.86e-2)" "unprognostic (2.05e-1)" "unprognostic (8.07e-3)" "unprognostic (1.36e-2)" "unprognostic (3.03e-1)" MRGPRX4 MRGX4 ENSG00000179817 "MAS related GPR family member X4" Q96LA9 11 18172837-18174280 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 11 "skin cancer: 2.7" NA NA "Cluster 69: Skin cancer - ECM organization" 4 MRI1 "MGC3207, MRDI, mtnA, Ypr118w" ENSG00000037757 "Methylthioribose-1-phosphate isomerase 1" Q9BV20 19 13764522-13774282 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Amino-acid biosynthesis, Methionine biosynthesis" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042744, CAB045988" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" No No 13000 "Cluster 13: Non-specific - Mitochondria" "Cluster 64: Non-specific - Transcription" "Cluster 30: White matter - Myelination" "Cluster 23: Non-specific - Transcription" "Cluster 98: Neurons - Neurotransmission & signaling" 8 "Nucleoplasm, Cytosol" "Nucleoli fibrillar center" "CAB045988: , HPA042744: " "unprognostic (4.02e-2)" "unprognostic (2.42e-1)" "potential prognostic favorable (8.40e-4)" "unprognostic (1.56e-1)" "unprognostic (3.18e-1)" "unprognostic (4.07e-1)" "unprognostic (2.74e-1)" "unprognostic (1.62e-1)" "unprognostic (1.44e-1)" "unprognostic (6.47e-2)" "unprognostic (1.35e-2)" "unprognostic (1.04e-1)" "unprognostic (3.68e-2)" "unprognostic (1.60e-1)" "unprognostic (1.97e-1)" "unprognostic (1.89e-2)" "unprognostic (6.27e-2)" "unprognostic (5.69e-2)" "unprognostic (7.70e-3)" "unprognostic (1.17e-1)" "unprognostic (5.55e-2)" "unprognostic (7.92e-2)" "unprognostic (6.93e-2)" "unprognostic (1.43e-3)" "potential prognostic favorable (8.29e-4)" "unprognostic (3.33e-3)" "potential prognostic unfavorable (9.41e-4)" "unprognostic (2.11e-2)" "unprognostic (1.72e-1)" "unprognostic (3.85e-1)" "unprognostic (8.42e-2)" MRLN "Linc-RAM, LINC00948, M1, MLN, MUSER1" ENSG00000227877 Myoregulin P0DMT0 10 59736692-59756041 "Predicted intracellular proteins, Transporters" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "skeletal muscle: 176.7;tongue: 137.2" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 116.0;Epididymal efferent duct ciliated cells: 94.4;Fallopian tube ciliated cells: 101.5;Lacrimal acinar cells: 34.4;Myonuclei: 45.5;Respiratory ciliated cells: 24.8;Rod photoreceptor cells: 69.9;Thymic myoid cells: 84.3" "Group enriched" "Detected in many" 5 "choroid plexus epithelial cell: 13.0;upper rhombic lip: 22.4" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 11.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in some" "Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in many" 11 "cerebellum: 21.6" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 35: Non-specific - DNA binding" "Cluster 1: Neuronal - Visual perception" "Cluster 107: Ciliated cells - Cilia assembly & function" "unprognostic (4.65e-3)" "unprognostic (2.94e-2)" "unprognostic (3.80e-2)" "unprognostic (6.17e-2)" "unprognostic (2.37e-3)" "unprognostic (1.27e-2)" "unprognostic (5.48e-2)" "unprognostic (7.54e-2)" "unprognostic (8.43e-2)" "unprognostic (8.00e-2)" "unprognostic (2.17e-1)" "unprognostic (7.42e-2)" "unprognostic (4.14e-1)" "unprognostic (3.22e-2)" MRM1 FLJ22578 ENSG00000278619 "Mitochondrial rRNA methyltransferase 1" Q6IN84 17 36601583-36608964 "Predicted intracellular proteins" "rRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 4.4;Brain inhibitory neurons: 6.0;Choroid plexus epithelial cells: 4.9;Distal convoluted tubule cells: 5.5;Enteric stem cells: 5.5;Enteric transient amplifying cells: 5.4;Loop of henle epithelial cells: 4.9;Microglia: 5.3;Oocytes: 4.6;Other brain neurons: 4.9;Papillary tip epithelial cells: 4.6;Podocytes: 4.4;Proximal tubule cells: 6.9;Renal collecting duct intercalated cells: 4.3;Renal collecting duct principal cells: 4.4;Renal connecting tubule cells: 4.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021598 Supported Supported Mitochondria NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 91 Mitochondria "HPA021598: " "unprognostic (1.67e-1)" "unprognostic (3.93e-2)" "unprognostic (1.23e-2)" "unprognostic (4.89e-2)" "unprognostic (3.85e-2)" "unprognostic (2.81e-1)" "unprognostic (7.53e-2)" "unprognostic (6.33e-2)" "unprognostic (2.12e-2)" "unprognostic (1.02e-1)" "unprognostic (1.39e-1)" "unprognostic (1.92e-1)" "unprognostic (2.03e-2)" "potential prognostic unfavorable (1.35e-4)" "unprognostic (1.28e-1)" "unprognostic (1.49e-1)" "unprognostic (1.87e-1)" "unprognostic (1.40e-2)" "unprognostic (1.96e-1)" "unprognostic (3.38e-1)" "unprognostic (1.59e-2)" "unprognostic (2.95e-1)" "unprognostic (1.88e-1)" "unprognostic (4.41e-2)" "unprognostic (9.23e-2)" "unprognostic (1.83e-1)" "unprognostic (7.40e-2)" "unprognostic (2.74e-1)" MRM2 "FJH1, FTSJ2, RRMJ2" ENSG00000122687 "Mitochondrial rRNA methyltransferase 2" Q9UI43 7 2234195-2242205 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "rRNA processing" "Methyltransferase, Transferase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 4.2;Bergmann glia: 7.4;Brain excitatory neurons: 8.2;Brain inhibitory neurons: 6.6;Choroid plexus epithelial cells: 5.1;Distal convoluted tubule cells: 4.8;Ependymal cells: 3.6;Loop of henle epithelial cells: 7.8;Microglia: 12.4;Oligodendrocyte progenitor cells: 5.8;Oligodendrocytes: 7.0;Other brain neurons: 9.0;Papillary tip epithelial cells: 9.7;Proximal tubule cells: 5.6;Renal collecting duct intercalated cells: 4.7;Renal collecting duct principal cells: 7.5;Renal connecting tubule cells: 3.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019826, HPA049622" Uncertain NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 67: Non-specific - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" 34 "HPA019826: , HPA049622: " "unprognostic (1.90e-1)" "unprognostic (1.18e-2)" "unprognostic (1.29e-1)" "unprognostic (4.05e-3)" "unprognostic (1.81e-1)" "unprognostic (5.09e-3)" "unprognostic (7.19e-3)" "potential prognostic unfavorable (1.11e-4)" "potential prognostic unfavorable (9.09e-4)" "unprognostic (4.29e-3)" "unprognostic (1.25e-2)" "unprognostic (5.85e-2)" "potential prognostic unfavorable (6.50e-6)" "potential prognostic unfavorable (9.20e-4)" "unprognostic (1.17e-1)" "potential prognostic favorable (4.80e-4)" "unprognostic (5.87e-2)" "unprognostic (2.56e-2)" "unprognostic (1.88e-2)" "unprognostic (3.03e-1)" "unprognostic (8.08e-2)" "unprognostic (1.22e-2)" "unprognostic (3.40e-1)" "unprognostic (1.12e-1)" "unprognostic (2.51e-1)" "unprognostic (2.65e-1)" "unprognostic (5.27e-1)" "unprognostic (2.90e-2)" "unprognostic (1.71e-1)" MRM3 "FLJ10581, HC90, RMTL1, RNMTL1" ENSG00000171861 "Mitochondrial rRNA methyltransferase 3" Q9HC36 17 782353-792509 "Predicted intracellular proteins" "rRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 127.8;Late spermatids: 47.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skin - Keratinocyte (other), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022534, HPA023031, HPA023292" Enhanced Supported Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 24: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 42: Non-specific - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 46 Mitochondria "HPA022534: , HPA023031: , HPA023292: " "unprognostic (9.24e-2)" "unprognostic (1.14e-1)" "unprognostic (6.27e-2)" "unprognostic (3.64e-2)" "unprognostic (5.80e-2)" "unprognostic (1.44e-1)" "unprognostic (2.14e-2)" "unprognostic (1.47e-1)" "unprognostic (1.48e-1)" "potential prognostic favorable (5.68e-7)" "unprognostic (7.08e-3)" "unprognostic (3.77e-3)" "unprognostic (2.81e-1)" "unprognostic (2.35e-3)" "unprognostic (1.77e-1)" "unprognostic (1.88e-1)" "unprognostic (5.43e-2)" "unprognostic (7.65e-2)" "unprognostic (1.26e-1)" "unprognostic (3.36e-2)" "unprognostic (9.24e-2)" "unprognostic (9.30e-2)" "unprognostic (5.13e-2)" "unprognostic (3.82e-2)" "unprognostic (6.36e-2)" "unprognostic (2.23e-1)" "unprognostic (2.92e-1)" "unprognostic (9.93e-2)" "unprognostic (1.37e-2)" MRNIP "C5orf45, DKFZp686L2452, LOC51149, MGC65027, MGC78537" ENSG00000161010 "MRN complex interacting protein" Q6NTE8 5 179835133-179862173 "Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 33.2;Bergmann glia: 33.6;Brain excitatory neurons: 46.9;Brain inhibitory neurons: 38.3;Choroid plexus epithelial cells: 40.2;Distal convoluted tubule cells: 34.5;Ependymal cells: 60.8;Loop of henle epithelial cells: 31.7;Microglia: 29.0;Oligodendrocyte progenitor cells: 22.2;Oligodendrocytes: 28.4;Other brain neurons: 37.4;Papillary tip epithelial cells: 23.9;Podocytes: 22.7;Proximal tubule cells: 31.4;Renal collecting duct intercalated cells: 19.5;Renal collecting duct principal cells: 32.6;Renal connecting tubule cells: 27.7" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" 8 "Prostate Adenocarcinoma (TCGA): 40.8;Uterine Corpus Endometrial Carcinoma (TCGA): 71.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in many" 6 "Bile duct cancer: 23.0" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043975 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 102: Non-specific - Mixed function" 10 "Plasma membrane, Cytosol" "HPA043975: " "potential prognostic favorable (2.19e-4)" "unprognostic (7.69e-2)" "unprognostic (2.83e-1)" "unprognostic (1.76e-1)" "unprognostic (2.10e-2)" "unprognostic (2.13e-1)" "unprognostic (9.82e-2)" "unprognostic (3.83e-3)" "unprognostic (7.78e-3)" "unprognostic (1.23e-2)" "unprognostic (4.72e-2)" "unprognostic (6.18e-2)" "unprognostic (2.33e-3)" "unprognostic (3.64e-1)" "unprognostic (1.51e-1)" "unprognostic (9.98e-2)" "unprognostic (1.85e-2)" "unprognostic (1.66e-1)" "unprognostic (1.94e-3)" "unprognostic (7.12e-3)" "unprognostic (1.20e-1)" "unprognostic (5.12e-3)" "potential prognostic favorable (8.82e-4)" "unprognostic (1.11e-2)" "unprognostic (2.49e-1)" "unprognostic (2.70e-1)" "unprognostic (6.89e-2)" "unprognostic (1.39e-1)" MRO "B29, C18orf3, FLJ30140" ENSG00000134042 Maestro Q9BYG7 18 50795120-50825402 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 36.3;kidney: 22.5;testis: 27.1" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 21.3;Astrocytes: 47.3;Choroid plexus epithelial cells: 13.7;Enterocytes: 21.4;Kupffer cells: 34.8;Proximal tubule cells: 30.0;Retinal pigment epithelial cells: 12.8;Sertoli cells: 103.7" "Cell type enhanced" "Detected in many" "astrocyte: 50.0" "Cancer enriched" "Detected in some" 6 "Glioblastoma Multiforme (TCGA): 10.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Bone cancer: 1.9" "Breast - Fibroblasts, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Sinusoid Endothelial cells, Minor Salivary Gland - Macrophages, Spleen - Macrophages, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022011 Approved NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 39: Astrocytes - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" "HPA022011: " "unprognostic (2.49e-1)" "unprognostic (2.14e-1)" "unprognostic (9.69e-2)" "unprognostic (1.49e-2)" "unprognostic (2.42e-3)" "unprognostic (8.09e-2)" "unprognostic (1.76e-1)" "unprognostic (6.33e-2)" "unprognostic (2.03e-1)" "unprognostic (3.01e-3)" MROH1 "HEATR7A, KIAA1833" ENSG00000179832 "Maestro heat like repeat family member 1" Q8NDA8 8 144148016-144261927 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 46.1" "Cell type enhanced" "Detected in many" "Gonadotrophs: 208.4;Retinal ganglion cells: 189.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Stomach - Gastric mucous cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024287, HPA044465" Approved Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 70: Non-specific - Protein processing" "Cluster 24: Neurons - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 19 Nucleoplasm Cytosol "HPA024287: , HPA044465: " "unprognostic (2.34e-1)" "unprognostic (7.90e-2)" "unprognostic (4.75e-3)" "unprognostic (1.47e-1)" "unprognostic (3.68e-1)" "unprognostic (1.38e-2)" "unprognostic (3.16e-1)" "unprognostic (2.81e-1)" "unprognostic (3.71e-2)" "unprognostic (1.11e-1)" "unprognostic (3.79e-1)" "potential prognostic favorable (2.79e-6)" "unprognostic (9.88e-2)" "unprognostic (2.75e-1)" "unprognostic (7.31e-2)" "unprognostic (7.27e-3)" "unprognostic (1.10e-1)" "unprognostic (2.88e-2)" "unprognostic (2.57e-2)" "unprognostic (1.72e-1)" "unprognostic (7.34e-3)" "unprognostic (3.43e-1)" "unprognostic (9.44e-2)" "unprognostic (5.01e-2)" "unprognostic (1.86e-1)" "unprognostic (6.37e-3)" "unprognostic (1.60e-1)" "unprognostic (6.31e-2)" "unprognostic (1.07e-1)" MROH2A HEATR7B1 ENSG00000185038 "Maestro heat like repeat family member 2A" A6NES4 2 233775679-233833423 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 1.6;thyroid gland: 1.5" "Cell type enhanced" "Detected in some" "Early primary spermatocytes: 2.1;Early spermatids: 5.0;Esophageal basal cells: 5.0;Hepatocytes: 2.6;Late primary spermatocytes: 2.9;Late spermatids: 8.3;Pituitary stem cells: 2.8;Proximal tubule cells: 10.8;Renal connecting tubule cells: 2.2;Undifferentiated spermatogonia: 3.9;Urothelial cells: 12.6" "Cell type enriched" "Detected in some" 8 "deep-layer near-projecting: 12.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Bone cancer: 2.0" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA052107 Uncertain Uncertain Cytosol NA NA "Cluster 39: Testis - Nuclear processes" "Cluster 7: Liver cancer - Metabolism" "Cluster 69: Urothelial cells - Basic cellular functions" Cytosol "HPA052107: " "unprognostic (2.20e-2)" MROH2B "DKFZp781F0822, FLJ40243, HEATR7B2, SPIF" ENSG00000171495 "Maestro heat like repeat family member 2B" Q7Z745 5 40998017-41071342 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 193 "testis: 28.2" "Group enriched" "Detected in some" 5 "Adipocytes: 29.9;Early spermatids: 21.4;Late primary spermatocytes: 35.8;Late spermatids: 74.3" "Cell type enhanced" "Detected in single" "fibroblast: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA059457 Enhanced Approved "Cytosol,Acrosome,Mid piece" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 72: Neuronal - Signal transduction" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "Acrosome, Mid piece" Cytosol "HPA059457: " MROH5 FLJ43860 ENSG00000226807 "Maestro heat like repeat family member 5 (gene/pseudogene)" 8 141433829-141507230 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 14 "testis: 1.5" "Cell type enhanced" "Detected in some" "Early spermatids: 144.2;Late primary spermatocytes: 46.7;Late spermatids: 203.7" "Cell type enriched" "Detected in single" 10 "vascular associated smooth muscle cell: 8.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" MROH6 C8orf73 ENSG00000204839 "Maestro heat like repeat family member 6" A6NGR9 8 143566192-143572772 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 23.1" "Cell type enhanced" "Detected in some" "Astrocytes: 2.6;Brain excitatory neurons: 2.2;Brain inhibitory neurons: 2.0;Loop of henle epithelial cells: 3.1;Microglia: 2.2;Papillary tip epithelial cells: 7.8;Proximal tubule cells: 5.4;Renal collecting duct intercalated cells: 2.3;Renal collecting duct principal cells: 7.8;Renal connecting tubule cells: 2.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA068049 Uncertain Approved Nucleoplasm NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 1 Nucleoplasm "HPA068049: " "unprognostic (8.70e-2)" "unprognostic (7.66e-2)" "unprognostic (2.33e-2)" "unprognostic (1.49e-1)" "unprognostic (1.53e-3)" "unprognostic (5.97e-2)" "unprognostic (5.75e-2)" "unprognostic (5.15e-3)" "unprognostic (2.20e-1)" "unprognostic (2.39e-2)" "unprognostic (1.02e-1)" "unprognostic (1.17e-1)" "unprognostic (5.95e-2)" "unprognostic (1.99e-1)" "potential prognostic unfavorable (9.59e-4)" "unprognostic (1.42e-3)" "unprognostic (2.73e-1)" "unprognostic (2.33e-2)" "unprognostic (4.96e-2)" "unprognostic (2.07e-1)" "unprognostic (1.79e-1)" "unprognostic (2.07e-2)" "unprognostic (1.94e-1)" MROH7 "C1orf175, FLJ46354, HEATR8" ENSG00000184313 "Maestro heat like repeat family member 7" Q68CQ1 1 54641754-54710266 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 50.7" "Cell type enriched" "Detected in some" 5 "Late spermatids: 490.2" "Group enriched" "Detected in some" 4 "astrocyte: 5.0;Bergmann glia: 2.0;ependymal cell: 2.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Late spermatids" "Not detected" "Not detected" "Region enriched" "Detected in single" 6 "cerebellum: 2.2" HPA071840 Enhanced NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" "HPA071840: " "unprognostic (4.09e-2)" "unprognostic (1.29e-1)" MROH8 "C20orf131, C20orf132, dJ621N11.3, dJ621N11.4" ENSG00000101353 "Maestro heat like repeat family member 8" 20 37101226-37179588 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "testis: 17.4" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 71.5;Myonuclei: 67.7;Retinal ganglion cells: 96.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 2.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA058316, HPA060298" Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 31: Non-specific - Transcription" "Cluster 6: Leukemia - Signal transduction" "Cluster 55: Myocytes - Oxidative muscle function" Nucleoplasm "Vesicles, Cytosol" "HPA058316: , HPA060298: " "unprognostic (1.45e-1)" "unprognostic (1.32e-1)" "unprognostic (1.81e-2)" "unprognostic (1.43e-2)" "unprognostic (4.73e-2)" "unprognostic (2.49e-2)" "unprognostic (3.79e-1)" "unprognostic (1.64e-3)" "unprognostic (2.06e-1)" "unprognostic (1.03e-1)" "unprognostic (6.41e-3)" "unprognostic (2.41e-1)" MROH9 "ARMC11, C1orf129, FLJ23550" ENSG00000117501 "Maestro heat like repeat family member 9" Q5TGP6 1 170935526-171064765 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 2.4;testis: 1.5" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 169.9;Epicardial cells: 52.3;Fallopian tube ciliated cells: 77.7;Fibro-adipogenic progenitors: 87.0;Foveolar cells: 43.6;Late primary spermatocytes: 75.7;Oligodendrocyte progenitor cells: 86.6;Respiratory ciliated cells: 386.4" "Cell type enriched" "Detected in some" 9 "oligodendrocyte precursor cell: 179.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 107: Ciliated cells - Cilia assembly & function" MRPL1 BM022 ENSG00000169288 "Mitochondrial ribosomal protein L1" Q9BYD6 4 77862830-77952785 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "T-cells: 229.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" HPA043656 Supported Approved Mitochondria NA NA 18000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 14: Neurons - Synaptic function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 9: T-cells - Adaptive immunity: Regulation" 64 Mitochondria "HPA043656: " "unprognostic (2.03e-1)" "potential prognostic unfavorable (8.11e-4)" "unprognostic (2.21e-1)" "unprognostic (3.71e-2)" "unprognostic (2.78e-2)" "unprognostic (2.65e-3)" "unprognostic (8.10e-2)" "unprognostic (2.03e-1)" "potential prognostic unfavorable (2.52e-4)" "unprognostic (7.14e-3)" "potential prognostic favorable (2.09e-7)" "unprognostic (4.36e-3)" "unprognostic (8.31e-3)" "potential prognostic unfavorable (2.70e-4)" "unprognostic (2.63e-2)" "unprognostic (1.14e-3)" "unprognostic (2.62e-2)" "unprognostic (3.26e-1)" "unprognostic (1.32e-1)" "unprognostic (5.02e-2)" "unprognostic (1.66e-2)" "unprognostic (7.56e-2)" "unprognostic (4.37e-2)" "unprognostic (2.22e-2)" "unprognostic (3.70e-3)" "unprognostic (9.82e-2)" "unprognostic (1.47e-2)" "unprognostic (7.96e-2)" "unprognostic (1.21e-1)" "unprognostic (2.36e-1)" "unprognostic (1.55e-1)" MRPL10 "L10MT, MGC17973, MRP-L10, MRP-L8, MRPL8, RPML8" ENSG00000159111 "Mitochondrial ribosomal protein L10" Q7Z7H8 17 47823272-47831541 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 107.2;Migrating cytotrophoblasts: 98.9;Syncytiotrophoblasts: 84.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021234, HPA029885" Enhanced Supported Mitochondria NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 45: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 79 Mitochondria "HPA021234: , HPA029885: " "unprognostic (5.86e-2)" "unprognostic (1.15e-2)" "unprognostic (4.82e-2)" "unprognostic (6.95e-3)" "unprognostic (8.87e-2)" "unprognostic (7.49e-2)" "unprognostic (1.13e-1)" "unprognostic (5.54e-2)" "unprognostic (1.62e-3)" "unprognostic (7.84e-2)" "potential prognostic favorable (7.59e-5)" "unprognostic (7.10e-3)" "unprognostic (2.53e-1)" "validated prognostic unfavorable (6.98e-6)" "validated prognostic unfavorable (8.02e-7)" "unprognostic (2.02e-3)" "unprognostic (2.48e-2)" "unprognostic (3.09e-1)" "unprognostic (2.83e-2)" "unprognostic (9.03e-2)" "unprognostic (2.89e-2)" "unprognostic (5.12e-2)" "unprognostic (2.86e-1)" "unprognostic (4.36e-2)" "unprognostic (8.15e-2)" "unprognostic (7.62e-2)" "unprognostic (2.74e-1)" "unprognostic (4.68e-2)" "unprognostic (2.63e-1)" "unprognostic (3.00e-1)" "unprognostic (2.66e-1)" MRPL11 ENSG00000174547 "Mitochondrial ribosomal protein L11" Q9Y3B7 11 66435075-66466738 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enteric transient amplifying cells: 179.0;Esophageal basal cells: 259.2;Extravillous trophoblasts: 217.2;Migrating cytotrophoblasts: 219.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057685 Approved Supported "Primary cilium,Mitochondria" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 73 Mitochondria "Primary cilium" "HPA057685: " "unprognostic (3.85e-2)" "unprognostic (4.17e-1)" "unprognostic (1.41e-2)" "unprognostic (1.19e-2)" "unprognostic (7.08e-2)" "unprognostic (3.33e-2)" "unprognostic (4.67e-1)" "unprognostic (9.30e-2)" "unprognostic (1.43e-2)" "unprognostic (8.52e-2)" "potential prognostic favorable (5.43e-5)" "unprognostic (3.27e-1)" "unprognostic (1.60e-2)" "validated prognostic unfavorable (2.42e-4)" "validated prognostic unfavorable (2.02e-5)" "validated prognostic unfavorable (7.81e-4)" "validated prognostic unfavorable (2.96e-4)" "unprognostic (8.98e-2)" "unprognostic (1.11e-1)" "unprognostic (2.48e-2)" "unprognostic (1.93e-1)" "potential prognostic unfavorable (9.92e-4)" "unprognostic (2.12e-1)" "unprognostic (1.76e-1)" "potential prognostic favorable (2.87e-4)" "unprognostic (8.83e-2)" "unprognostic (4.51e-2)" "unprognostic (3.98e-2)" "unprognostic (2.98e-2)" "unprognostic (9.16e-2)" "unprognostic (2.48e-1)" MRPL12 "MRPL7, MRPL7/L12, RPML12" ENSG00000262814 "Mitochondrial ribosomal protein L12" P52815 17 81703367-81707517 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Colonocytes: 12.8;Enteric stem cells: 11.9;Enteric transient amplifying cells: 18.3;Enterocytes: 9.1;Ependymal cells: 9.1;Foveolar cells: 15.1;Gastric chief cells: 32.8;Mucous neck cells: 11.7;Other brain neurons: 10.6;Parietal cells: 70.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022853, HPA023043" Supported Supported Mitochondria NA NA 410000 "Cluster 13: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cellular respiration" "Cluster 44: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 123 Mitochondria "HPA022853: , HPA023043: " "unprognostic (1.41e-2)" "unprognostic (4.00e-1)" "unprognostic (2.32e-1)" "unprognostic (3.88e-1)" "unprognostic (2.02e-2)" "unprognostic (4.15e-2)" "unprognostic (3.72e-2)" "unprognostic (4.56e-1)" "unprognostic (1.40e-2)" "unprognostic (1.85e-2)" "unprognostic (6.56e-3)" "unprognostic (1.49e-3)" "unprognostic (3.25e-2)" "validated prognostic unfavorable (3.38e-4)" "validated prognostic unfavorable (7.80e-4)" "potential prognostic unfavorable (4.86e-4)" "unprognostic (1.91e-3)" "unprognostic (2.38e-1)" "unprognostic (2.80e-2)" "unprognostic (1.34e-2)" "unprognostic (1.41e-2)" "unprognostic (4.52e-2)" "unprognostic (5.47e-2)" "unprognostic (3.39e-1)" "unprognostic (6.39e-2)" "unprognostic (1.25e-1)" "unprognostic (6.42e-2)" "unprognostic (4.69e-2)" "unprognostic (2.00e-1)" "unprognostic (2.02e-2)" "unprognostic (6.92e-2)" MRPL13 "L13, L13A, L13mt, RPL13, RPML13" ENSG00000172172 "Mitochondrial ribosomal protein L13" Q9BYD1 8 120380761-120445402 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal basal cells: 209.2;Esophageal suprabasal cells: 248.3;Extravillous trophoblasts: 208.4;Parietal cells: 224.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060899 Approved NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 40: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 136 "HPA060899: " "unprognostic (8.65e-2)" "potential prognostic unfavorable (2.29e-4)" "unprognostic (3.02e-1)" "unprognostic (2.46e-3)" "unprognostic (2.46e-1)" "unprognostic (2.12e-1)" "unprognostic (4.49e-2)" "unprognostic (5.09e-2)" "unprognostic (2.38e-2)" "unprognostic (5.45e-2)" "unprognostic (1.15e-3)" "unprognostic (1.17e-1)" "unprognostic (1.07e-1)" "unprognostic (1.51e-3)" "potential prognostic unfavorable (2.30e-4)" "potential prognostic unfavorable (2.72e-6)" "unprognostic (1.25e-2)" "unprognostic (1.29e-1)" "unprognostic (2.22e-1)" "unprognostic (1.10e-2)" "unprognostic (8.84e-2)" "validated prognostic unfavorable (7.93e-4)" "validated prognostic unfavorable (1.26e-5)" "unprognostic (5.47e-2)" "unprognostic (1.42e-2)" "unprognostic (3.58e-1)" "unprognostic (1.80e-2)" "unprognostic (1.92e-1)" "unprognostic (2.52e-1)" "unprognostic (1.68e-1)" "unprognostic (4.74e-1)" MRPL14 "MRP-L32, RPML32" ENSG00000180992 "Mitochondrial ribosomal protein L14" Q6P1L8 6 44113451-44127452 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 175.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 434.6;Alveolar cells type 2: 537.9;Hepatocytes: 414.2;Hofbauer cells: 476.4;Late primary spermatocytes: 427.1;Transitional alveolar cells: 423.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038769, HPA076790" Uncertain Supported Mitochondria NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 21: Non-specific - Metabolism" "Cluster 28: Non-specific - Nuclear processes" "Cluster 81: Alveolar cells - Lung function" 16 Mitochondria "HPA038769: , HPA076790: " "unprognostic (9.19e-3)" "unprognostic (1.70e-1)" "unprognostic (1.61e-1)" "unprognostic (7.39e-2)" "unprognostic (2.03e-1)" "unprognostic (3.97e-2)" "unprognostic (1.71e-1)" "unprognostic (1.52e-2)" "unprognostic (2.31e-2)" "unprognostic (2.50e-3)" "unprognostic (1.15e-2)" "unprognostic (7.67e-2)" "unprognostic (1.71e-2)" "unprognostic (9.95e-3)" "potential prognostic unfavorable (2.42e-4)" "unprognostic (2.10e-1)" "unprognostic (7.88e-2)" "unprognostic (2.38e-2)" "unprognostic (1.64e-2)" "potential prognostic favorable (4.27e-4)" "unprognostic (2.53e-1)" "unprognostic (5.12e-3)" "unprognostic (4.98e-1)" "unprognostic (1.78e-1)" "unprognostic (2.42e-1)" "unprognostic (1.01e-1)" "unprognostic (8.91e-3)" "unprognostic (9.54e-2)" "unprognostic (1.80e-1)" "unprognostic (2.63e-3)" "unprognostic (2.40e-1)" MRPL15 "HSPC145, L15mt, MRP-L15, MRP-L7, RPML7" ENSG00000137547 "Mitochondrial ribosomal protein L15" Q9P015 8 54135241-54148514 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 273.0;tongue: 260.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 189.6;Extravillous trophoblasts: 178.6;Migrating cytotrophoblasts: 203.5;Syncytiotrophoblasts: 251.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044425 Enhanced Supported Nucleoplasm,Mitochondria NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cellular respiration" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 40: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 74 Mitochondria Nucleoplasm "HPA044425: " "unprognostic (2.44e-1)" "unprognostic (1.35e-2)" "unprognostic (2.10e-1)" "unprognostic (1.30e-1)" "unprognostic (1.87e-1)" "unprognostic (1.33e-1)" "unprognostic (2.71e-1)" "unprognostic (3.79e-1)" "unprognostic (1.23e-2)" "unprognostic (1.96e-3)" "unprognostic (1.64e-2)" "unprognostic (5.89e-3)" "unprognostic (4.34e-2)" "unprognostic (1.75e-2)" "potential prognostic unfavorable (2.79e-4)" "potential prognostic unfavorable (6.08e-5)" "unprognostic (3.02e-2)" "unprognostic (3.54e-1)" "unprognostic (7.84e-2)" "unprognostic (9.88e-2)" "unprognostic (6.10e-2)" "potential prognostic unfavorable (6.25e-4)" "unprognostic (4.07e-2)" "unprognostic (4.02e-1)" "unprognostic (2.47e-2)" "unprognostic (1.80e-1)" "unprognostic (1.25e-1)" "unprognostic (7.08e-2)" "unprognostic (1.22e-1)" "unprognostic (2.39e-3)" "unprognostic (1.15e-1)" MRPL16 "FLJ20484, PNAS-111" ENSG00000166902 "Mitochondrial ribosomal protein L16" Q9NX20 11 59806140-59810778 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054133 Supported NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cellular respiration" "Cluster 23: Choroid plexus - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 49 "HPA054133: " "unprognostic (4.08e-2)" "unprognostic (1.20e-3)" "unprognostic (1.30e-2)" "unprognostic (1.19e-1)" "unprognostic (1.53e-2)" "unprognostic (3.81e-2)" "unprognostic (5.27e-2)" "unprognostic (1.67e-1)" "unprognostic (1.18e-2)" "unprognostic (2.09e-3)" "potential prognostic favorable (9.03e-5)" "unprognostic (4.83e-2)" "unprognostic (4.18e-3)" "unprognostic (9.91e-2)" "unprognostic (1.99e-1)" "potential prognostic unfavorable (4.13e-4)" "unprognostic (1.94e-3)" "unprognostic (1.86e-1)" "unprognostic (1.51e-1)" "unprognostic (7.78e-3)" "unprognostic (1.24e-1)" "potential prognostic unfavorable (3.56e-4)" "unprognostic (1.05e-1)" "potential prognostic unfavorable (5.72e-5)" "unprognostic (3.15e-2)" "unprognostic (4.73e-2)" "unprognostic (1.05e-1)" "unprognostic (5.46e-2)" "unprognostic (2.95e-1)" "unprognostic (1.40e-1)" "unprognostic (7.39e-2)" MRPL17 "MRP-L26, RPML26" ENSG00000158042 "Mitochondrial ribosomal protein L17" Q9NRX2 11 6680385-6683340 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 157.4;Esophageal suprabasal cells: 137.8;Extravillous trophoblasts: 173.9;Late primary spermatocytes: 136.1;Megakaryocytes: 148.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043666, HPA050552" Uncertain NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 23: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 60 "HPA043666: , HPA050552: " "unprognostic (1.76e-2)" "unprognostic (2.90e-2)" "unprognostic (4.32e-2)" "unprognostic (2.61e-2)" "unprognostic (1.23e-1)" "unprognostic (4.29e-2)" "unprognostic (4.16e-2)" "unprognostic (4.69e-2)" "unprognostic (4.81e-3)" "unprognostic (3.89e-3)" "unprognostic (1.92e-1)" "unprognostic (3.44e-2)" "unprognostic (1.43e-1)" "potential prognostic unfavorable (5.83e-4)" "unprognostic (5.91e-3)" "potential prognostic unfavorable (7.50e-4)" "unprognostic (1.23e-3)" "unprognostic (1.92e-1)" "unprognostic (1.77e-1)" "unprognostic (9.09e-2)" "unprognostic (1.35e-1)" "unprognostic (5.91e-2)" "unprognostic (1.38e-1)" "unprognostic (3.82e-1)" "unprognostic (9.14e-3)" "unprognostic (6.36e-2)" "unprognostic (1.67e-1)" "unprognostic (1.64e-1)" "unprognostic (2.20e-1)" "unprognostic (1.87e-3)" "unprognostic (2.05e-1)" MRPL18 HSPC071 ENSG00000112110 "Mitochondrial ribosomal protein L18" Q9H0U6 6 159789812-159798436 "Predicted intracellular proteins, Ribosomal proteins" Transport "Chaperone, Ribonucleoprotein, Ribosomal protein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pancreatic duct cells: 488.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028774, HPA028775" Enhanced Supported Mitochondria NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 75: Non-specific - Chaperones and protein folding" 142 Mitochondria "HPA028774: , HPA028775: " "unprognostic (2.91e-2)" "potential prognostic unfavorable (2.43e-5)" "unprognostic (4.58e-2)" "unprognostic (1.13e-1)" "unprognostic (1.87e-1)" "unprognostic (1.43e-1)" "unprognostic (9.11e-2)" "unprognostic (1.57e-1)" "unprognostic (1.22e-2)" "unprognostic (5.14e-2)" "unprognostic (4.26e-2)" "potential prognostic unfavorable (3.23e-4)" "unprognostic (1.40e-2)" "validated prognostic unfavorable (2.61e-4)" "validated prognostic unfavorable (4.19e-5)" "unprognostic (2.43e-2)" "unprognostic (2.26e-2)" "unprognostic (1.78e-3)" "unprognostic (8.41e-2)" "unprognostic (4.55e-2)" "unprognostic (2.61e-1)" "unprognostic (2.51e-1)" "unprognostic (1.16e-1)" "unprognostic (4.30e-2)" "unprognostic (2.63e-1)" "unprognostic (1.73e-1)" "unprognostic (7.43e-2)" "unprognostic (2.16e-1)" "unprognostic (2.53e-1)" "unprognostic (7.58e-2)" "unprognostic (1.72e-2)" MRPL19 "KIAA0104, MRP-L15, RLX1, RPML15" ENSG00000115364 "Mitochondrial ribosomal protein L19" P49406 2 75646783-75690851 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 254.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046805, HPA056622" Approved Supported Mitochondria NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 76: Non-specific - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 44 Mitochondria "HPA046805: , HPA056622: " "unprognostic (9.22e-2)" "unprognostic (3.83e-2)" "unprognostic (3.25e-1)" "unprognostic (2.80e-3)" "unprognostic (1.53e-3)" "unprognostic (1.08e-1)" "unprognostic (5.67e-2)" "unprognostic (2.74e-2)" "unprognostic (1.16e-2)" "unprognostic (1.02e-2)" "potential prognostic favorable (9.33e-6)" "unprognostic (9.43e-2)" "unprognostic (1.38e-1)" "unprognostic (1.06e-2)" "unprognostic (2.37e-1)" "unprognostic (7.50e-3)" "unprognostic (6.96e-2)" "unprognostic (1.69e-1)" "unprognostic (1.39e-1)" "unprognostic (1.93e-2)" "potential prognostic unfavorable (8.61e-5)" "potential prognostic unfavorable (5.63e-6)" "unprognostic (1.82e-1)" "unprognostic (1.50e-1)" "unprognostic (1.92e-1)" "unprognostic (1.08e-1)" "unprognostic (2.22e-2)" "unprognostic (1.99e-1)" "unprognostic (2.12e-1)" "unprognostic (8.06e-2)" "unprognostic (1.43e-1)" MRPL2 "CGI-22, MRP-L14, RPML14" ENSG00000112651 "Mitochondrial ribosomal protein L2" Q5T653 6 43054029-43059438 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enteric transient amplifying cells: 45.7;Enterocytes: 45.3;Parietal cells: 61.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007455, HPA064814" Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 37: Neurons - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 15: Non-specific - Protein processing" 133 Mitochondria Nucleoplasm "HPA007455: , HPA064814: " "potential prognostic unfavorable (3.95e-4)" "unprognostic (2.10e-1)" "unprognostic (1.80e-2)" "unprognostic (8.32e-3)" "unprognostic (2.03e-1)" "unprognostic (3.75e-1)" "unprognostic (1.51e-2)" "unprognostic (6.83e-2)" "unprognostic (3.04e-1)" "unprognostic (1.84e-2)" "unprognostic (1.13e-2)" "unprognostic (4.05e-2)" "unprognostic (1.06e-2)" "unprognostic (1.17e-2)" "unprognostic (1.38e-2)" "unprognostic (1.14e-2)" "unprognostic (1.33e-1)" "unprognostic (9.79e-3)" "unprognostic (1.66e-1)" "potential prognostic favorable (8.19e-4)" "unprognostic (3.35e-1)" "unprognostic (6.52e-2)" "unprognostic (1.25e-1)" "unprognostic (3.53e-1)" "unprognostic (1.06e-1)" "unprognostic (1.61e-2)" "unprognostic (1.23e-1)" "unprognostic (2.33e-2)" "unprognostic (1.83e-1)" "unprognostic (3.06e-1)" "unprognostic (2.85e-1)" MRPL20 FLJ10024 ENSG00000242485 "Mitochondrial ribosomal protein L20" Q9BYC9 1 1401909-1407293 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal suprabasal cells: 523.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047074 Supported Supported Mitochondria NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 37: Non-specific - mRNA processing" "Cluster 97: Non-specific - Cellular respiration" 51 Mitochondria "HPA047074: " "unprognostic (5.10e-2)" "unprognostic (1.11e-1)" "unprognostic (4.25e-1)" "unprognostic (4.77e-2)" "potential prognostic favorable (5.78e-4)" "unprognostic (3.64e-1)" "unprognostic (3.15e-2)" "unprognostic (7.47e-2)" "unprognostic (6.07e-2)" "potential prognostic unfavorable (2.65e-4)" "potential prognostic favorable (2.62e-4)" "unprognostic (2.21e-2)" "unprognostic (1.56e-2)" "unprognostic (2.18e-2)" "potential prognostic unfavorable (5.64e-4)" "unprognostic (4.27e-1)" "unprognostic (4.14e-2)" "unprognostic (1.82e-1)" "unprognostic (8.73e-2)" "unprognostic (3.22e-2)" "unprognostic (1.19e-1)" "unprognostic (8.09e-2)" "unprognostic (1.37e-1)" "unprognostic (2.34e-1)" "unprognostic (3.16e-2)" "unprognostic (2.98e-2)" "unprognostic (1.77e-1)" "unprognostic (1.80e-1)" "unprognostic (9.16e-2)" "unprognostic (1.45e-1)" "unprognostic (5.82e-2)" MRPL21 ENSG00000197345 "Mitochondrial ribosomal protein L21" Q7Z2W9 11 68891276-68903835 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric progenitor cells: 237.1;Late spermatids: 287.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051657 Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cellular respiration" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 24: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 58 "Nucleoplasm, Mitochondria" "HPA051657: " "unprognostic (6.24e-3)" "unprognostic (5.40e-2)" "unprognostic (3.10e-2)" "unprognostic (1.14e-2)" "unprognostic (2.25e-2)" "unprognostic (2.04e-1)" "unprognostic (1.09e-1)" "unprognostic (3.94e-1)" "potential prognostic unfavorable (1.32e-4)" "unprognostic (8.10e-3)" "potential prognostic favorable (8.24e-4)" "unprognostic (2.26e-2)" "unprognostic (5.31e-2)" "unprognostic (7.48e-3)" "unprognostic (6.55e-3)" "validated prognostic unfavorable (1.98e-4)" "validated prognostic unfavorable (9.88e-5)" "unprognostic (8.97e-2)" "unprognostic (1.28e-1)" "unprognostic (1.65e-1)" "unprognostic (8.71e-2)" "unprognostic (1.95e-2)" "unprognostic (1.79e-3)" "unprognostic (2.45e-2)" "unprognostic (1.41e-1)" "unprognostic (4.71e-2)" "unprognostic (1.83e-2)" "unprognostic (1.91e-1)" "unprognostic (2.21e-1)" "unprognostic (1.11e-1)" "unprognostic (1.30e-1)" MRPL22 "HSPC158, MRP-L25, RPML25" ENSG00000082515 "Mitochondrial ribosomal protein L22" Q9NWU5 5 154941073-154969411 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric progenitor cells: 202.5;Late primary spermatocytes: 267.0;Oocytes: 239.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047063 Uncertain Approved Mitochondria NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 76: Non-specific - Metabolism" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 97: Non-specific - Cellular respiration" 14 Mitochondria "HPA047063: " "unprognostic (5.49e-2)" "unprognostic (3.54e-2)" "potential prognostic unfavorable (1.98e-5)" "unprognostic (3.89e-2)" "unprognostic (1.75e-2)" "unprognostic (8.99e-2)" "unprognostic (2.52e-1)" "unprognostic (5.10e-1)" "unprognostic (6.57e-3)" "unprognostic (1.92e-2)" "potential prognostic favorable (2.17e-4)" "unprognostic (3.18e-2)" "unprognostic (1.72e-1)" "unprognostic (1.22e-3)" "unprognostic (6.78e-2)" "potential prognostic unfavorable (3.40e-4)" "unprognostic (1.13e-1)" "unprognostic (1.77e-1)" "unprognostic (2.41e-1)" "unprognostic (1.40e-2)" "unprognostic (1.64e-1)" "validated prognostic unfavorable (2.64e-5)" "validated prognostic unfavorable (1.61e-4)" "unprognostic (4.95e-2)" "unprognostic (3.11e-2)" "unprognostic (1.13e-1)" "unprognostic (8.04e-2)" "unprognostic (2.36e-1)" "unprognostic (2.18e-1)" "unprognostic (6.17e-3)" "unprognostic (1.29e-1)" MRPL23 "L23MRP, RPL23L" ENSG00000214026 "Mitochondrial ribosomal protein L23" Q16540 11 1947278-1984522 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 174.7;Epididymal efferent duct ciliated cells: 159.9;Extravillous trophoblasts: 170.6;Parietal cells: 224.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA050406 Approved Approved "Nucleoli fibrillar center,Mitochondria" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 93 "Nucleoli fibrillar center, Mitochondria" "HPA050406: " "unprognostic (2.60e-2)" "unprognostic (7.22e-2)" "unprognostic (1.26e-1)" "potential prognostic favorable (7.26e-5)" "unprognostic (1.09e-1)" "unprognostic (3.28e-2)" "potential prognostic unfavorable (4.75e-4)" "unprognostic (3.84e-2)" "unprognostic (2.98e-1)" "unprognostic (1.47e-1)" "unprognostic (1.50e-2)" "unprognostic (2.68e-2)" "unprognostic (1.16e-1)" "unprognostic (7.47e-2)" "potential prognostic unfavorable (5.00e-4)" "unprognostic (3.01e-1)" "unprognostic (1.15e-1)" "unprognostic (2.10e-1)" "unprognostic (5.31e-2)" "unprognostic (1.54e-1)" "unprognostic (1.08e-1)" "unprognostic (3.17e-1)" "unprognostic (7.23e-2)" "unprognostic (1.45e-1)" "unprognostic (3.12e-1)" "unprognostic (6.45e-2)" "unprognostic (3.90e-2)" "unprognostic (3.75e-1)" "unprognostic (2.87e-1)" "unprognostic (2.05e-3)" "unprognostic (3.93e-2)" MRPL24 MRP-L18 ENSG00000143314 "Mitochondrial ribosomal protein L24" Q96A35 1 156737303-156741590 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 203.2;Hepatocytes: 161.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030295, HPA054323" Approved NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 76: Non-specific - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 97: Non-specific - Cellular respiration" 68 "HPA030295: , HPA054323: " "unprognostic (1.06e-1)" "unprognostic (5.51e-2)" "unprognostic (2.20e-1)" "unprognostic (7.20e-2)" "unprognostic (5.25e-2)" "unprognostic (5.51e-2)" "unprognostic (4.68e-1)" "unprognostic (1.66e-1)" "unprognostic (1.75e-2)" "unprognostic (1.29e-3)" "unprognostic (2.52e-2)" "unprognostic (8.94e-2)" "unprognostic (1.35e-2)" "unprognostic (1.65e-2)" "unprognostic (1.51e-1)" "unprognostic (6.76e-3)" "unprognostic (2.09e-2)" "unprognostic (8.48e-2)" "unprognostic (3.88e-1)" "unprognostic (2.08e-1)" "unprognostic (3.68e-1)" "unprognostic (5.78e-2)" "unprognostic (2.15e-3)" "unprognostic (6.35e-2)" "unprognostic (2.05e-1)" "unprognostic (9.63e-3)" "unprognostic (1.75e-1)" "unprognostic (3.88e-1)" "unprognostic (4.68e-2)" "unprognostic (3.42e-1)" "unprognostic (1.52e-3)" MRPL27 ENSG00000108826 "Mitochondrial ribosomal protein L27" Q9P0M9 17 50367857-50373207 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 279.6;Esophageal suprabasal cells: 271.6;Migrating cytotrophoblasts: 272.6;Parietal cells: 311.2;Syncytiotrophoblasts: 316.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021416 Approved NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 97 "HPA021416: " "unprognostic (3.50e-1)" "unprognostic (3.89e-2)" "unprognostic (7.32e-2)" "potential prognostic favorable (7.66e-4)" "unprognostic (4.10e-2)" "unprognostic (2.08e-2)" "unprognostic (2.38e-2)" "unprognostic (2.47e-2)" "unprognostic (2.98e-2)" "unprognostic (6.76e-3)" "unprognostic (2.83e-2)" "unprognostic (7.99e-3)" "unprognostic (2.42e-1)" "unprognostic (7.99e-3)" "unprognostic (5.79e-3)" "unprognostic (6.62e-3)" "unprognostic (1.83e-2)" "unprognostic (1.98e-1)" "unprognostic (1.08e-1)" "unprognostic (1.28e-2)" "unprognostic (4.21e-1)" "unprognostic (3.62e-2)" "unprognostic (2.38e-1)" "unprognostic (5.54e-2)" "unprognostic (1.98e-1)" "unprognostic (2.05e-2)" "unprognostic (2.62e-1)" "unprognostic (9.36e-2)" "unprognostic (2.20e-1)" "unprognostic (2.80e-2)" "unprognostic (3.30e-1)" MRPL28 "MAAT1, p15" ENSG00000086504 "Mitochondrial ribosomal protein L28" Q13084 16 366969-371289 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 218.0;Late spermatids: 365.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030594, CAB033542, HPA055589" Supported Supported Mitochondria NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 14: Neurons - Synaptic function" "Cluster 54: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 118 Mitochondria "CAB033542: , HPA030594: , HPA055589: " "unprognostic (1.94e-1)" "unprognostic (7.80e-2)" "unprognostic (3.81e-1)" "unprognostic (3.48e-1)" "unprognostic (1.64e-1)" "unprognostic (2.77e-1)" "unprognostic (4.35e-2)" "unprognostic (1.99e-1)" "unprognostic (1.73e-2)" "unprognostic (1.86e-1)" "unprognostic (1.44e-2)" "unprognostic (1.71e-1)" "unprognostic (8.73e-2)" "unprognostic (1.07e-2)" "unprognostic (8.43e-3)" "unprognostic (2.84e-3)" "unprognostic (2.15e-2)" "unprognostic (2.83e-3)" "unprognostic (1.26e-1)" "unprognostic (2.63e-2)" "unprognostic (1.39e-1)" "unprognostic (1.95e-3)" "unprognostic (3.68e-3)" "unprognostic (2.82e-1)" "unprognostic (1.47e-1)" "unprognostic (1.87e-1)" "unprognostic (2.27e-2)" "unprognostic (1.03e-1)" "unprognostic (1.97e-1)" "unprognostic (2.64e-1)" "unprognostic (1.54e-1)" MRPL3 "MRL3, RPML3" ENSG00000114686 "Mitochondrial ribosomal protein L3" P09001 3 131462212-131502983 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043665, HPA060132" Approved NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 17: Non-specific - RNA processing" 76 "HPA043665: , HPA060132: " "unprognostic (9.37e-2)" "unprognostic (4.21e-3)" "unprognostic (2.75e-1)" "unprognostic (1.91e-1)" "unprognostic (2.42e-2)" "unprognostic (1.79e-1)" "unprognostic (3.85e-2)" "unprognostic (2.82e-2)" "unprognostic (5.18e-3)" "unprognostic (1.56e-2)" "unprognostic (4.07e-3)" "unprognostic (1.17e-1)" "unprognostic (4.13e-2)" "validated prognostic unfavorable (4.31e-7)" "validated prognostic unfavorable (6.54e-5)" "validated prognostic unfavorable (9.30e-4)" "validated prognostic unfavorable (3.96e-4)" "unprognostic (8.76e-3)" "unprognostic (2.13e-1)" "unprognostic (2.08e-1)" "unprognostic (4.03e-3)" "potential prognostic unfavorable (1.72e-6)" "unprognostic (1.45e-1)" "unprognostic (3.11e-2)" "unprognostic (2.07e-2)" "unprognostic (4.02e-2)" "unprognostic (1.59e-1)" "unprognostic (1.61e-1)" "unprognostic (2.36e-1)" "unprognostic (2.11e-3)" "unprognostic (2.75e-1)" MRPL30 "MRP-L28, RPML28" ENSG00000185414 "Mitochondrial ribosomal protein L30" Q8TCC3 2 99181152-99199561 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Skin - Mitotic cells (Skin)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047255 Approved NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 17: Non-specific - RNA processing" 17 "HPA047255: " "unprognostic (3.68e-1)" "unprognostic (2.91e-3)" "unprognostic (2.89e-1)" "unprognostic (2.63e-2)" "unprognostic (2.21e-1)" "unprognostic (1.54e-1)" "unprognostic (2.38e-1)" "unprognostic (1.78e-2)" "unprognostic (5.84e-2)" "unprognostic (7.92e-3)" "potential prognostic favorable (1.38e-7)" "unprognostic (2.29e-3)" "unprognostic (1.31e-1)" "validated prognostic unfavorable (7.25e-4)" "validated prognostic unfavorable (3.30e-4)" "unprognostic (5.66e-2)" "unprognostic (7.22e-2)" "unprognostic (4.47e-2)" "unprognostic (3.87e-2)" "unprognostic (1.04e-1)" "unprognostic (5.56e-3)" "unprognostic (1.77e-1)" "unprognostic (2.12e-3)" "unprognostic (9.31e-2)" "unprognostic (1.04e-3)" "unprognostic (9.91e-2)" "unprognostic (2.00e-2)" "unprognostic (4.97e-2)" "unprognostic (1.21e-1)" "unprognostic (6.93e-2)" "unprognostic (2.41e-2)" MRPL32 "bMRP-59b, HSPC283, L32mt, MRP-L32" ENSG00000106591 "Mitochondrial ribosomal protein L32" Q9BYC8 7 42932376-42948958 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048965 Uncertain "Intracellular and membrane" Other NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 76: Non-specific - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 103: Non-specific - Basic cellular processes" 51 "HPA048965: " "unprognostic (2.47e-3)" "unprognostic (1.23e-2)" "unprognostic (5.50e-1)" "unprognostic (1.35e-3)" "unprognostic (3.50e-2)" "unprognostic (4.04e-2)" "unprognostic (1.24e-3)" "unprognostic (4.13e-1)" "unprognostic (1.79e-2)" "unprognostic (3.12e-2)" "potential prognostic favorable (1.78e-9)" "unprognostic (3.50e-2)" "potential prognostic favorable (7.46e-4)" "unprognostic (8.60e-2)" "unprognostic (2.29e-2)" "unprognostic (3.15e-3)" "unprognostic (5.13e-3)" "unprognostic (2.85e-2)" "unprognostic (1.52e-1)" "unprognostic (5.24e-2)" "unprognostic (1.31e-1)" "unprognostic (1.63e-1)" "unprognostic (1.51e-2)" "unprognostic (2.75e-2)" "unprognostic (1.42e-1)" "unprognostic (1.03e-1)" "unprognostic (7.17e-3)" "unprognostic (2.56e-2)" "unprognostic (4.56e-2)" "unprognostic (4.08e-1)" "unprognostic (1.10e-1)" MRPL33 "C2orf1, RPL33L" ENSG00000243147 "Mitochondrial ribosomal protein L33" O75394 2 27771717-27988087 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ocular epithelial cells: 544.3;Parietal cells: 779.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066872 Approved NA NA "Cluster 41: Basophils - Unknown function" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 100: Stratified epithelial cells - Barrier functions" 19 "HPA066872: " "unprognostic (2.96e-1)" "unprognostic (2.61e-3)" "unprognostic (4.63e-2)" "unprognostic (2.71e-1)" "unprognostic (2.34e-1)" "unprognostic (1.10e-1)" "unprognostic (1.00e-1)" "unprognostic (4.43e-1)" "potential prognostic unfavorable (4.88e-4)" "potential prognostic unfavorable (8.66e-4)" "potential prognostic favorable (1.96e-4)" "unprognostic (3.19e-2)" "unprognostic (1.38e-1)" "validated prognostic unfavorable (8.11e-4)" "validated prognostic unfavorable (7.74e-4)" "unprognostic (1.99e-1)" "unprognostic (2.01e-1)" "unprognostic (3.34e-2)" "unprognostic (1.23e-1)" "unprognostic (2.87e-2)" "unprognostic (1.19e-1)" "unprognostic (3.37e-1)" "unprognostic (3.60e-2)" "unprognostic (1.84e-2)" "unprognostic (5.04e-2)" "unprognostic (6.54e-2)" "unprognostic (6.84e-2)" "unprognostic (1.30e-1)" "unprognostic (1.72e-1)" "unprognostic (3.41e-1)" "unprognostic (1.59e-1)" MRPL34 "L34mt, MGC24974, MGC2633" ENSG00000130312 "Mitochondrial ribosomal protein L34" Q9BQ48 19 17292609-17306843 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 322.6;Late primary spermatocytes: 448.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049276 Uncertain Supported Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 23: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 13 Mitochondria "HPA049276: " "unprognostic (1.04e-1)" "unprognostic (6.22e-3)" "unprognostic (8.16e-2)" "unprognostic (3.34e-2)" "unprognostic (1.87e-1)" "unprognostic (1.74e-1)" "unprognostic (5.63e-2)" "unprognostic (1.56e-2)" "unprognostic (1.94e-2)" "unprognostic (2.02e-1)" "unprognostic (5.43e-3)" "unprognostic (2.35e-2)" "unprognostic (1.65e-2)" "unprognostic (1.21e-1)" "unprognostic (1.25e-1)" "unprognostic (6.50e-2)" "unprognostic (5.85e-2)" "unprognostic (1.16e-2)" "unprognostic (9.68e-3)" "unprognostic (4.29e-3)" "unprognostic (2.12e-1)" "potential prognostic favorable (8.13e-4)" "unprognostic (2.21e-2)" "unprognostic (1.20e-1)" "unprognostic (1.62e-1)" "unprognostic (3.17e-1)" "unprognostic (1.03e-1)" "unprognostic (2.22e-1)" "unprognostic (2.99e-2)" "unprognostic (5.55e-2)" "unprognostic (2.73e-1)" MRPL35 ENSG00000132313 "Mitochondrial ribosomal protein L35" Q9NZE8 2 86199355-86213790 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Parietal cells: 145.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043482 Uncertain NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 97: Non-specific - Cellular respiration" 39 "HPA043482: " "potential prognostic unfavorable (2.30e-4)" "unprognostic (4.24e-2)" "unprognostic (3.38e-1)" "unprognostic (2.91e-1)" "unprognostic (4.03e-2)" "unprognostic (2.79e-3)" "unprognostic (8.83e-2)" "unprognostic (1.58e-1)" "unprognostic (3.63e-3)" "unprognostic (5.79e-2)" "unprognostic (1.86e-3)" "unprognostic (1.92e-1)" "unprognostic (1.54e-2)" "validated prognostic unfavorable (1.53e-5)" "validated prognostic unfavorable (4.41e-4)" "potential prognostic unfavorable (4.76e-4)" "unprognostic (3.46e-2)" "unprognostic (1.52e-1)" "unprognostic (9.23e-3)" "unprognostic (1.69e-1)" "unprognostic (1.51e-3)" "unprognostic (1.42e-3)" "unprognostic (4.23e-1)" "unprognostic (2.15e-2)" "unprognostic (2.62e-1)" "unprognostic (2.32e-3)" "unprognostic (1.05e-2)" "unprognostic (3.40e-2)" "unprognostic (9.46e-2)" "unprognostic (2.20e-1)" "unprognostic (2.93e-2)" MRPL36 "L36mt, MRP-L36, PRPL36, RPMJ" ENSG00000171421 "Mitochondrial ribosomal protein L36" Q9P0J6 5 1798385-1801366 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 430.9;Esophageal basal cells: 220.8;Esophageal suprabasal cells: 202.6;Late primary spermatocytes: 498.7;Late spermatids: 598.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047238 Approved Supported "Nuclear bodies,Mitochondria" No No "Cluster 13: Non-specific - Mitochondria" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 29: Non-specific - Unknown function" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 1 Mitochondria "Nuclear bodies" "HPA047238: " "potential prognostic unfavorable (6.54e-5)" "potential prognostic unfavorable (9.99e-4)" "unprognostic (3.86e-2)" "unprognostic (1.28e-2)" "unprognostic (6.78e-2)" "unprognostic (1.45e-1)" "unprognostic (1.92e-3)" "unprognostic (1.26e-1)" "unprognostic (2.38e-2)" "unprognostic (8.11e-2)" "unprognostic (2.72e-3)" "unprognostic (1.11e-2)" "unprognostic (1.10e-2)" "potential prognostic unfavorable (2.78e-5)" "unprognostic (4.69e-3)" "unprognostic (5.47e-2)" "unprognostic (2.92e-3)" "unprognostic (1.28e-2)" "unprognostic (2.75e-1)" "unprognostic (1.61e-1)" "unprognostic (1.20e-1)" "unprognostic (9.19e-2)" "unprognostic (1.84e-1)" "unprognostic (4.68e-2)" "unprognostic (1.94e-1)" "unprognostic (3.68e-1)" "unprognostic (1.37e-2)" "unprognostic (2.50e-1)" "unprognostic (2.64e-1)" "unprognostic (3.64e-1)" "unprognostic (1.32e-2)" MRPL37 "MRP-L2, RPML2" ENSG00000116221 "Mitochondrial ribosomal protein L37" Q9BZE1 1 54184041-54225464 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 191.0;Esophageal suprabasal cells: 174.5;Extravillous trophoblasts: 167.4;Hepatocytes: 201.2;Migrating cytotrophoblasts: 173.5;Oocytes: 188.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Stomach - Mitotic cells (Stomach), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025767, HPA025826, HPA025951" Supported Supported Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 5: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 97: Non-specific - Cellular respiration" 105 Mitochondria "HPA025767: , HPA025826: , HPA025951: " "unprognostic (1.12e-1)" "unprognostic (1.32e-1)" "unprognostic (6.26e-2)" "unprognostic (3.45e-1)" "potential prognostic favorable (1.70e-4)" "unprognostic (5.16e-2)" "unprognostic (1.98e-1)" "unprognostic (4.00e-2)" "unprognostic (6.10e-2)" "unprognostic (5.66e-3)" "potential prognostic favorable (3.80e-4)" "unprognostic (1.07e-1)" "unprognostic (5.93e-2)" "validated prognostic unfavorable (1.20e-6)" "validated prognostic unfavorable (8.56e-4)" "unprognostic (5.56e-3)" "unprognostic (2.15e-3)" "unprognostic (9.24e-2)" "unprognostic (5.14e-1)" "unprognostic (2.31e-1)" "unprognostic (4.15e-2)" "potential prognostic unfavorable (3.94e-4)" "unprognostic (7.61e-2)" "unprognostic (1.16e-1)" "unprognostic (3.28e-3)" "unprognostic (2.59e-1)" "unprognostic (2.90e-1)" "unprognostic (5.40e-2)" "unprognostic (3.17e-1)" "unprognostic (1.14e-1)" "unprognostic (3.92e-1)" MRPL38 "HSPC262, MGC4810, MRP-L3, RPML3" ENSG00000204316 "Mitochondrial ribosomal protein L38" Q96DV4 17 75898644-75905093 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 23.2;Bergmann glia: 24.7;Brain excitatory neurons: 18.0;Brain inhibitory neurons: 17.8;Choroid plexus epithelial cells: 13.1;Enteric stem cells: 14.1;Enteric transient amplifying cells: 16.1;Ependymal cells: 22.2;Microglia: 15.8;Oligodendrocyte progenitor cells: 16.3;Oligodendrocytes: 24.6;Other brain neurons: 22.1;Tuft cells: 11.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023054, HPA023135, HPA075099" Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" 92 Mitochondria "HPA023054: , HPA023135: , HPA075099: " "unprognostic (2.26e-1)" "unprognostic (2.96e-2)" "unprognostic (5.39e-2)" "unprognostic (3.52e-2)" "unprognostic (2.31e-3)" "unprognostic (1.02e-1)" "unprognostic (2.44e-1)" "unprognostic (5.29e-3)" "unprognostic (4.05e-2)" "unprognostic (2.96e-2)" "unprognostic (6.19e-2)" "unprognostic (1.55e-1)" "unprognostic (1.08e-2)" "unprognostic (3.74e-3)" "potential prognostic unfavorable (4.91e-4)" "unprognostic (7.89e-2)" "unprognostic (5.02e-3)" "unprognostic (2.66e-1)" "unprognostic (1.78e-1)" "unprognostic (2.70e-2)" "unprognostic (6.58e-3)" "unprognostic (5.62e-3)" "unprognostic (5.99e-2)" "unprognostic (1.41e-2)" "unprognostic (1.75e-1)" "unprognostic (4.84e-2)" "unprognostic (8.55e-2)" "unprognostic (1.19e-1)" "unprognostic (3.57e-1)" "unprognostic (8.24e-2)" "unprognostic (3.86e-1)" MRPL39 "C21orf92, FLJ20451, L39mt, MGC104174, MGC3400, MRP-L5, MSTP003, PRED22, PRED66, RPML5" ENSG00000154719 "Mitochondrial ribosomal protein L39" Q9NYK5 21 25585656-25607517 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 234.3;Late primary spermatocytes: 347.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018331 Approved Supported Mitochondria NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 76: Non-specific - Metabolism" "Cluster 34: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 43 Mitochondria "HPA018331: " "unprognostic (2.63e-1)" "potential prognostic unfavorable (2.45e-4)" "unprognostic (1.11e-2)" "unprognostic (1.21e-1)" "unprognostic (1.81e-3)" "unprognostic (6.19e-2)" "unprognostic (1.36e-1)" "unprognostic (1.48e-2)" "potential prognostic unfavorable (5.47e-4)" "unprognostic (7.89e-2)" "potential prognostic favorable (2.39e-5)" "unprognostic (2.58e-2)" "unprognostic (3.00e-2)" "potential prognostic unfavorable (1.92e-4)" "unprognostic (1.30e-1)" "unprognostic (1.34e-2)" "unprognostic (1.61e-1)" "unprognostic (2.89e-2)" "unprognostic (6.41e-2)" "unprognostic (5.19e-2)" "unprognostic (3.78e-1)" "potential prognostic unfavorable (1.64e-4)" "unprognostic (2.07e-1)" "unprognostic (3.29e-2)" "unprognostic (2.51e-3)" "unprognostic (1.38e-1)" "unprognostic (2.04e-2)" "unprognostic (2.93e-1)" "unprognostic (3.38e-1)" "unprognostic (1.54e-1)" "unprognostic (8.69e-2)" MRPL4 CGI-28 ENSG00000105364 "Mitochondrial ribosomal protein L4" Q9BYD3 19 10251901-10260055 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 228.6;Esophageal basal cells: 233.4;Esophageal suprabasal cells: 178.8;Migrating cytotrophoblasts: 182.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051261 Approved NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 23: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 49 "HPA051261: " "unprognostic (1.22e-1)" "unprognostic (8.11e-2)" "unprognostic (5.84e-1)" "unprognostic (1.81e-2)" "unprognostic (1.01e-2)" "unprognostic (8.73e-2)" "unprognostic (1.05e-1)" "unprognostic (1.37e-1)" "unprognostic (1.47e-1)" "unprognostic (5.92e-3)" "unprognostic (4.17e-3)" "unprognostic (1.57e-2)" "unprognostic (3.94e-2)" "unprognostic (2.02e-2)" "potential prognostic unfavorable (1.70e-4)" "unprognostic (2.38e-2)" "unprognostic (1.50e-2)" "unprognostic (3.50e-2)" "unprognostic (3.77e-2)" "unprognostic (1.41e-2)" "unprognostic (2.65e-2)" "unprognostic (5.54e-3)" "unprognostic (3.36e-1)" "unprognostic (3.65e-3)" "unprognostic (1.12e-2)" "unprognostic (1.71e-2)" "unprognostic (2.10e-1)" "unprognostic (5.53e-3)" "unprognostic (3.94e-2)" "unprognostic (3.44e-1)" "unprognostic (3.22e-1)" MRPL40 "MRP-L22, NLVCF" ENSG00000185608 "Mitochondrial ribosomal protein L40" Q9NQ50 22 19432545-19436075 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 226.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006181 Uncertain Supported Nucleoli,Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 66: Non-specific - Mitochondria" "Cluster 97: Non-specific - Cellular respiration" 61 Mitochondria Nucleoli "HPA006181: " "unprognostic (6.27e-3)" "unprognostic (5.94e-2)" "unprognostic (6.30e-2)" "unprognostic (7.08e-3)" "unprognostic (2.29e-1)" "unprognostic (8.89e-2)" "unprognostic (3.41e-2)" "unprognostic (3.94e-3)" "unprognostic (1.12e-3)" "unprognostic (1.34e-2)" "potential prognostic unfavorable (2.34e-4)" "unprognostic (9.54e-2)" "unprognostic (1.77e-3)" "unprognostic (1.55e-1)" "unprognostic (3.07e-1)" "unprognostic (6.12e-2)" "unprognostic (2.57e-1)" "unprognostic (7.53e-3)" "unprognostic (2.17e-1)" "unprognostic (4.27e-2)" "unprognostic (2.40e-1)" "unprognostic (4.15e-2)" "unprognostic (1.09e-2)" "potential prognostic favorable (2.40e-4)" "unprognostic (3.37e-2)" "unprognostic (5.16e-2)" "unprognostic (1.59e-1)" "unprognostic (2.41e-1)" "unprognostic (2.11e-1)" "unprognostic (2.81e-1)" "unprognostic (1.17e-1)" MRPL41 "BMRP, MRP-L27, MRPL27, PIG3, RPML27" ENSG00000182154 "Mitochondrial ribosomal protein L41" Q8IXM3 9 137551879-137552555 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Apoptosis, Cell cycle" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 826.1" "Cell type enhanced" "Detected in all" "Colonocytes: 592.4;Hepatocytes: 998.8;Late spermatids: 1160.4;Parietal cells: 1028.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Heart muscle - Cardiomyocytes, Prostate - Prostate glandular cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024550, HPA027160" Supported Supported Mitochondria NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 33: Neurons - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 97: Non-specific - Cellular respiration" 66 Mitochondria "HPA024550: , HPA027160: " "unprognostic (4.54e-2)" "unprognostic (1.05e-1)" "unprognostic (1.97e-1)" "unprognostic (1.08e-1)" "unprognostic (1.96e-1)" "unprognostic (7.75e-3)" "potential prognostic unfavorable (5.32e-4)" "unprognostic (4.39e-1)" "unprognostic (2.98e-2)" "unprognostic (2.88e-1)" "unprognostic (2.38e-3)" "unprognostic (2.10e-2)" "unprognostic (8.42e-3)" "unprognostic (1.06e-1)" "unprognostic (3.61e-2)" "unprognostic (1.14e-1)" "unprognostic (3.51e-1)" "unprognostic (6.77e-2)" "unprognostic (6.53e-2)" "unprognostic (3.08e-1)" "unprognostic (1.19e-1)" "unprognostic (1.97e-3)" "unprognostic (3.01e-1)" "unprognostic (1.02e-1)" "unprognostic (5.18e-2)" "unprognostic (3.80e-1)" "unprognostic (2.89e-2)" "unprognostic (1.02e-1)" "unprognostic (1.23e-1)" "unprognostic (1.83e-1)" "unprognostic (2.74e-2)" MRPL42 "HSPC204, MRP-L31, MRPL31, MRPS32, PTD007, RPML31" ENSG00000198015 "Mitochondrial ribosomal protein L42" Q9Y6G3 12 93467514-93516214 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 332.0;Late primary spermatocytes: 598.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039398 Approved Supported "Plasma membrane,Mitochondria" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 76: Non-specific - Metabolism" "Cluster 55: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 140 Mitochondria "Plasma membrane" "HPA039398: " "unprognostic (4.38e-1)" "unprognostic (3.16e-2)" "unprognostic (2.48e-2)" "unprognostic (4.65e-2)" "unprognostic (1.91e-2)" "unprognostic (7.00e-2)" "unprognostic (7.12e-2)" "unprognostic (2.11e-1)" "unprognostic (4.99e-2)" "unprognostic (2.52e-2)" "potential prognostic favorable (4.19e-4)" "unprognostic (2.58e-2)" "unprognostic (1.70e-2)" "validated prognostic unfavorable (1.46e-6)" "validated prognostic unfavorable (3.13e-4)" "unprognostic (9.92e-3)" "unprognostic (3.81e-2)" "unprognostic (1.68e-2)" "unprognostic (4.84e-3)" "unprognostic (1.17e-1)" "unprognostic (2.11e-2)" "unprognostic (2.20e-2)" "unprognostic (1.73e-3)" "unprognostic (9.28e-2)" "unprognostic (1.81e-2)" "unprognostic (1.80e-1)" "unprognostic (5.61e-2)" "unprognostic (1.75e-1)" "unprognostic (1.60e-1)" "unprognostic (1.15e-1)" "unprognostic (1.68e-2)" MRPL43 bMRP36a ENSG00000055950 "Mitochondrial ribosomal protein L43" Q8N983 10 100969458-100987515 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 484.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073022 Approved Nucleoplasm,Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 24: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 13 "Nucleoplasm, Mitochondria" "HPA073022: " "unprognostic (1.87e-1)" "unprognostic (1.46e-1)" "unprognostic (7.91e-2)" "unprognostic (8.33e-2)" "unprognostic (9.57e-2)" "unprognostic (1.71e-1)" "unprognostic (2.61e-1)" "unprognostic (6.30e-3)" "unprognostic (5.57e-2)" "unprognostic (1.18e-1)" "potential prognostic favorable (1.79e-4)" "unprognostic (1.71e-1)" "unprognostic (9.27e-2)" "unprognostic (2.27e-1)" "unprognostic (1.43e-1)" "unprognostic (1.15e-1)" "unprognostic (3.41e-1)" "unprognostic (1.38e-1)" "unprognostic (2.92e-1)" "unprognostic (1.26e-1)" "unprognostic (1.64e-1)" "unprognostic (3.05e-2)" "unprognostic (1.67e-2)" "unprognostic (1.16e-1)" "unprognostic (1.24e-1)" "unprognostic (2.03e-1)" "unprognostic (3.85e-1)" "unprognostic (6.12e-2)" "unprognostic (4.10e-1)" "unprognostic (7.05e-2)" "unprognostic (2.83e-1)" MRPL44 "FLJ12701, FLJ13990" ENSG00000135900 "Mitochondrial ribosomal protein L44" Q9H9J2 2 223957463-223967714 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Endonuclease, Hydrolase, Nuclease, Ribonucleoprotein, Ribosomal protein, RNA-binding" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 114.3;Migrating cytotrophoblasts: 104.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038147, HPA038148" Approved Approved "Nucleoplasm,Nuclear bodies,Plasma membrane,Mitochondria" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 76 Mitochondria "Nucleoplasm, Nuclear bodies, Plasma membrane" "HPA038147: , HPA038148: " "unprognostic (4.88e-1)" "unprognostic (9.87e-3)" "unprognostic (4.67e-3)" "unprognostic (8.04e-2)" "unprognostic (1.21e-2)" "unprognostic (1.11e-2)" "unprognostic (1.87e-1)" "unprognostic (1.73e-1)" "unprognostic (9.55e-2)" "unprognostic (2.03e-1)" "validated prognostic favorable (6.62e-8)" "validated prognostic favorable (5.40e-4)" "unprognostic (1.18e-2)" "potential prognostic unfavorable (3.61e-5)" "unprognostic (7.02e-2)" "potential prognostic unfavorable (9.32e-4)" "unprognostic (1.19e-3)" "unprognostic (2.54e-1)" "unprognostic (1.59e-1)" "unprognostic (1.26e-2)" "unprognostic (2.31e-1)" "unprognostic (1.10e-1)" "unprognostic (2.51e-2)" "unprognostic (8.92e-2)" "unprognostic (1.50e-1)" "unprognostic (3.67e-1)" "unprognostic (9.89e-2)" "unprognostic (1.23e-1)" "unprognostic (3.12e-2)" "unprognostic (2.89e-1)" "unprognostic (1.21e-1)" MRPL45 "Mba1, MGC11321" ENSG00000278845 "Mitochondrial ribosomal protein L45" 17 38297023-38323217 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 15.9;Brain inhibitory neurons: 16.6;Choroid plexus epithelial cells: 14.5;Distal convoluted tubule cells: 33.1;Loop of henle epithelial cells: 27.2;Oligodendrocytes: 15.4;Other brain neurons: 16.9;Papillary tip epithelial cells: 21.3;Podocytes: 29.7;Proximal tubule cells: 29.0;Renal collecting duct intercalated cells: 22.2;Renal collecting duct principal cells: 20.9;Renal connecting tubule cells: 24.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023373, HPA023385" Enhanced Enhanced Mitochondria NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 24 Mitochondria "HPA023373: , HPA023385: " "unprognostic (1.23e-1)" "unprognostic (5.10e-2)" "unprognostic (2.07e-2)" "unprognostic (3.04e-3)" "unprognostic (3.05e-1)" "unprognostic (1.66e-1)" "unprognostic (4.32e-1)" "unprognostic (3.30e-2)" "unprognostic (4.05e-2)" "unprognostic (5.84e-2)" "unprognostic (3.90e-2)" "unprognostic (2.12e-2)" "unprognostic (1.38e-1)" "potential prognostic unfavorable (4.38e-5)" "unprognostic (4.50e-2)" "unprognostic (4.85e-2)" "unprognostic (2.46e-1)" "unprognostic (5.99e-1)" "unprognostic (1.14e-1)" "unprognostic (1.52e-1)" "unprognostic (3.16e-1)" "unprognostic (2.68e-2)" "unprognostic (3.20e-1)" "unprognostic (3.45e-3)" "unprognostic (2.92e-1)" "unprognostic (2.01e-1)" "unprognostic (3.61e-2)" "unprognostic (3.65e-1)" MRPL46 "C15orf4, LIECG2, P2ECSL" ENSG00000259494 "Mitochondrial ribosomal protein L46" Q9H2W6 15 88459477-88467390 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enteric stem cells: 19.0;Enteric transient amplifying cells: 21.3;Enterocytes: 15.7;Parietal cells: 35.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050166, HPA076046" Approved Supported "Nucleoplasm,Cell Junctions,Mitochondria,Cytosol" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 76: Non-specific - Metabolism" "Cluster 45: Non-specific - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 15: Non-specific - Protein processing" 75 Mitochondria "Nucleoplasm, Cell Junctions, Cytosol" "HPA050166: , HPA076046: " "unprognostic (2.25e-2)" "unprognostic (5.48e-2)" "unprognostic (2.42e-1)" "unprognostic (1.93e-3)" "unprognostic (3.47e-1)" "unprognostic (4.60e-2)" "unprognostic (3.40e-1)" "potential prognostic favorable (4.53e-4)" "unprognostic (2.94e-3)" "unprognostic (8.19e-3)" "validated prognostic favorable (3.18e-10)" "validated prognostic favorable (1.06e-4)" "unprognostic (9.76e-3)" "unprognostic (2.56e-2)" "unprognostic (1.75e-2)" "unprognostic (2.73e-2)" "unprognostic (9.84e-2)" "unprognostic (5.09e-2)" "unprognostic (3.25e-2)" "unprognostic (3.26e-2)" "unprognostic (5.24e-2)" "unprognostic (1.49e-1)" "unprognostic (2.93e-2)" "unprognostic (1.38e-1)" "unprognostic (4.69e-2)" "unprognostic (1.16e-1)" "unprognostic (6.10e-2)" "unprognostic (5.26e-2)" "unprognostic (1.93e-1)" "unprognostic (6.43e-2)" "unprognostic (1.70e-1)" MRPL47 "CGI-204, NCM1" ENSG00000136522 "Mitochondrial ribosomal protein L47" Q9HD33 3 179588285-179604649 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 352.6;Gastric progenitor cells: 288.4;Late primary spermatocytes: 728.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037553, HPA047779" Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 30 Mitochondria "HPA037553: , HPA047779: " "unprognostic (2.05e-3)" "unprognostic (7.32e-3)" "unprognostic (1.79e-2)" "unprognostic (1.83e-3)" "unprognostic (1.83e-1)" "unprognostic (5.16e-2)" "unprognostic (1.34e-1)" "unprognostic (3.98e-2)" "unprognostic (2.64e-3)" "potential prognostic unfavorable (1.08e-6)" "unprognostic (6.16e-2)" "unprognostic (7.25e-2)" "potential prognostic unfavorable (8.01e-4)" "validated prognostic unfavorable (4.93e-5)" "validated prognostic unfavorable (7.41e-4)" "validated prognostic unfavorable (1.88e-4)" "validated prognostic unfavorable (3.58e-4)" "unprognostic (3.90e-3)" "unprognostic (3.19e-3)" "unprognostic (2.05e-2)" "unprognostic (2.22e-2)" "unprognostic (1.45e-2)" "unprognostic (2.13e-2)" "unprognostic (3.19e-2)" "unprognostic (2.27e-1)" "unprognostic (1.91e-1)" "unprognostic (7.93e-2)" "unprognostic (5.01e-2)" "unprognostic (2.37e-1)" "unprognostic (1.93e-1)" "unprognostic (7.01e-2)" MRPL48 CGI-118 ENSG00000175581 "Mitochondrial ribosomal protein L48" Q96GC5 11 73787872-73865133 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040241, HPA040864" Approved Supported Mitochondria NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 48 Mitochondria "HPA040241: , HPA040864: " "unprognostic (6.99e-3)" "unprognostic (2.77e-2)" "unprognostic (9.43e-2)" "unprognostic (2.13e-1)" "unprognostic (7.32e-2)" "unprognostic (1.02e-1)" "unprognostic (2.41e-1)" "unprognostic (4.24e-2)" "unprognostic (8.51e-3)" "unprognostic (3.64e-1)" "unprognostic (3.80e-3)" "unprognostic (6.41e-2)" "unprognostic (1.82e-3)" "potential prognostic unfavorable (6.57e-4)" "unprognostic (3.23e-3)" "unprognostic (1.17e-1)" "unprognostic (2.86e-2)" "unprognostic (1.24e-2)" "unprognostic (1.07e-1)" "unprognostic (1.04e-1)" "unprognostic (3.93e-1)" "unprognostic (4.69e-2)" "unprognostic (1.15e-2)" "unprognostic (6.28e-2)" "unprognostic (3.13e-1)" "unprognostic (4.73e-1)" "unprognostic (1.64e-2)" "unprognostic (2.21e-1)" "unprognostic (1.37e-1)" "unprognostic (3.27e-1)" "unprognostic (2.49e-1)" MRPL49 "C11orf4, L49mt, NOF, NOF1" ENSG00000149792 "Mitochondrial ribosomal protein L49" Q13405 11 65122183-65127371 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 71.9;Esophageal apical cells: 118.9;Migrating cytotrophoblasts: 72.9;Syncytiotrophoblasts: 142.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046778 Approved NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 42 "HPA046778: " "unprognostic (1.58e-1)" "unprognostic (1.36e-3)" "unprognostic (1.61e-2)" "unprognostic (1.60e-2)" "unprognostic (1.12e-1)" "unprognostic (9.37e-2)" "unprognostic (2.53e-1)" "unprognostic (1.17e-1)" "unprognostic (1.95e-2)" "potential prognostic unfavorable (9.27e-6)" "potential prognostic favorable (7.92e-12)" "unprognostic (5.95e-3)" "unprognostic (4.81e-3)" "potential prognostic unfavorable (1.17e-4)" "unprognostic (1.03e-1)" "unprognostic (2.64e-1)" "potential prognostic unfavorable (7.57e-4)" "unprognostic (2.86e-1)" "unprognostic (8.76e-2)" "unprognostic (2.33e-1)" "unprognostic (1.26e-1)" "unprognostic (1.55e-3)" "unprognostic (3.71e-2)" "unprognostic (1.37e-1)" "unprognostic (7.13e-3)" "unprognostic (1.36e-1)" "unprognostic (4.69e-1)" "unprognostic (1.14e-1)" "unprognostic (2.00e-1)" "unprognostic (2.30e-1)" "unprognostic (3.73e-1)" MRPL50 "FLJ20493, MRP-L50" ENSG00000136897 "Mitochondrial ribosomal protein L50" Q8N5N7 9 101387633-101398618 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric progenitor cells: 182.0;Parietal cells: 210.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022925 Approved Supported Mitochondria,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 31: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 97: Non-specific - Cellular respiration" 145 Mitochondria Cytosol "HPA022925: " "unprognostic (7.48e-2)" "unprognostic (6.98e-3)" "unprognostic (8.29e-3)" "unprognostic (1.24e-1)" "unprognostic (2.24e-1)" "unprognostic (2.06e-1)" "unprognostic (1.34e-1)" "unprognostic (1.86e-2)" "unprognostic (2.29e-3)" "unprognostic (3.87e-1)" "validated prognostic favorable (6.30e-10)" "validated prognostic favorable (8.07e-4)" "unprognostic (1.44e-1)" "unprognostic (3.18e-3)" "unprognostic (2.05e-3)" "unprognostic (9.37e-3)" "unprognostic (1.83e-1)" "unprognostic (8.68e-2)" "unprognostic (2.86e-2)" "unprognostic (3.12e-1)" "unprognostic (1.52e-1)" "unprognostic (2.79e-2)" "unprognostic (1.35e-1)" "unprognostic (3.59e-2)" "unprognostic (1.18e-1)" "unprognostic (3.43e-2)" "unprognostic (3.60e-2)" "unprognostic (2.77e-2)" "unprognostic (2.77e-1)" "unprognostic (2.39e-1)" "unprognostic (2.82e-2)" MRPL51 "bMRP64, CDA09, HSPC241, MRP64" ENSG00000111639 "Mitochondrial ribosomal protein L51" Q4U2R6 12 6491886-6493841 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 903.5;Esophageal basal cells: 607.8;Esophageal suprabasal cells: 661.2;Late primary spermatocytes: 1345.7;Late spermatids: 630.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039923 Approved Supported Nucleoli,Mitochondria NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 96 Mitochondria Nucleoli "HPA039923: " "unprognostic (3.84e-1)" "unprognostic (1.57e-1)" "potential prognostic favorable (5.23e-4)" "unprognostic (9.24e-2)" "unprognostic (2.06e-1)" "unprognostic (1.07e-1)" "unprognostic (4.33e-1)" "unprognostic (2.40e-2)" "unprognostic (1.22e-1)" "unprognostic (1.82e-3)" "unprognostic (5.30e-2)" "unprognostic (5.82e-2)" "unprognostic (1.22e-1)" "validated prognostic unfavorable (2.44e-4)" "validated prognostic unfavorable (9.08e-10)" "potential prognostic unfavorable (4.53e-4)" "unprognostic (7.79e-2)" "unprognostic (1.50e-2)" "unprognostic (1.51e-1)" "unprognostic (7.34e-2)" "unprognostic (2.02e-1)" "unprognostic (2.64e-1)" "unprognostic (5.90e-3)" "unprognostic (2.49e-1)" "unprognostic (6.97e-2)" "unprognostic (3.18e-2)" "unprognostic (3.14e-2)" "unprognostic (1.62e-1)" "unprognostic (2.87e-1)" "unprognostic (2.06e-1)" "unprognostic (1.63e-1)" MRPL52 ENSG00000172590 "Mitochondrial ribosomal protein L52" Q86TS9 14 22829879-22835037 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal suprabasal cells: 405.6;Gastric progenitor cells: 588.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012319 Approved Supported Nucleoplasm,Mitochondria Yes No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 97: Non-specific - Cellular respiration" 98 Mitochondria Nucleoplasm "HPA012319: " "unprognostic (1.00e-1)" "unprognostic (1.18e-1)" "unprognostic (2.16e-2)" "unprognostic (6.91e-2)" "unprognostic (4.14e-3)" "unprognostic (1.06e-2)" "unprognostic (2.29e-1)" "unprognostic (1.82e-3)" "unprognostic (2.17e-3)" "unprognostic (6.11e-3)" "unprognostic (3.47e-3)" "unprognostic (1.83e-3)" "unprognostic (5.24e-2)" "unprognostic (1.74e-3)" "unprognostic (2.11e-3)" "unprognostic (2.11e-3)" "unprognostic (5.04e-2)" "unprognostic (1.68e-1)" "unprognostic (6.27e-2)" "unprognostic (1.98e-1)" "unprognostic (5.02e-2)" "unprognostic (2.46e-2)" "unprognostic (8.34e-2)" "unprognostic (9.06e-2)" "unprognostic (1.68e-1)" "unprognostic (2.14e-1)" "unprognostic (2.43e-2)" "unprognostic (3.85e-1)" "unprognostic (2.78e-1)" "unprognostic (8.81e-2)" "unprognostic (5.67e-2)" MRPL53 ENSG00000204822 "Mitochondrial ribosomal protein L53" Q96EL3 2 74471982-74472687 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 19.0;Enteric transient amplifying cells: 15.3;Enterocytes: 22.8;Epididymal efferent duct absorptive cells: 21.0;Epididymal efferent duct ciliated cells: 19.3;Epididymal principal cells: 29.7;Gastric chief cells: 16.4;Goblet cells: 16.5;Megakaryocytes: 18.5;Mucous neck cells: 15.4;Neuroendocrine cells: 22.0;Parietal cells: 33.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034612, HPA056185" Uncertain Supported Mitochondria NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 70: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 15: Non-specific - Protein processing" 89 Mitochondria "HPA034612: , HPA056185: " "unprognostic (1.59e-2)" "unprognostic (2.04e-1)" "unprognostic (1.94e-1)" "unprognostic (7.57e-2)" "unprognostic (1.56e-2)" "unprognostic (2.44e-2)" "unprognostic (3.34e-1)" "unprognostic (1.25e-3)" "unprognostic (8.01e-2)" "unprognostic (7.45e-2)" "unprognostic (1.82e-1)" "unprognostic (3.77e-2)" "unprognostic (4.77e-2)" "unprognostic (1.69e-3)" "potential prognostic unfavorable (5.80e-5)" "unprognostic (5.58e-2)" "unprognostic (1.10e-1)" "unprognostic (5.47e-2)" "unprognostic (1.65e-1)" "unprognostic (2.06e-1)" "unprognostic (1.78e-1)" "unprognostic (7.98e-2)" "unprognostic (4.12e-2)" "unprognostic (2.96e-1)" "unprognostic (2.64e-1)" "unprognostic (1.69e-1)" "unprognostic (1.46e-1)" "unprognostic (1.11e-1)" "unprognostic (1.55e-1)" "unprognostic (3.56e-1)" "unprognostic (1.14e-2)" MRPL54 ENSG00000183617 "Mitochondrial ribosomal protein L54" Q6P161 19 3762682-3768575 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 291.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042117, HPA046767" Uncertain Approved Mitochondria No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 70: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 23: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 14 Mitochondria "HPA042117: , HPA046767: " "unprognostic (2.05e-1)" "unprognostic (3.98e-1)" "unprognostic (2.98e-1)" "unprognostic (1.10e-2)" "unprognostic (2.17e-1)" "unprognostic (8.08e-3)" "unprognostic (8.79e-2)" "unprognostic (2.03e-1)" "unprognostic (9.89e-2)" "unprognostic (4.50e-2)" "unprognostic (6.94e-3)" "unprognostic (7.69e-3)" "potential prognostic favorable (6.62e-7)" "unprognostic (9.36e-3)" "unprognostic (5.96e-2)" "unprognostic (8.56e-3)" "unprognostic (7.84e-2)" "unprognostic (7.18e-2)" "unprognostic (3.70e-1)" "unprognostic (1.16e-1)" "unprognostic (2.44e-1)" "unprognostic (4.01e-2)" "unprognostic (1.59e-1)" "unprognostic (2.48e-1)" "unprognostic (1.57e-2)" "unprognostic (2.75e-1)" "unprognostic (2.77e-1)" "unprognostic (3.39e-1)" "unprognostic (2.53e-1)" "unprognostic (7.88e-2)" "potential prognostic favorable (1.98e-4)" MRPL55 ENSG00000162910 "Mitochondrial ribosomal protein L55" Q7Z7F7 1 228106679-228109312 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 231.7;Gastric progenitor cells: 274.3;Hepatocytes: 320.1;Late spermatids: 322.9;Oocytes: 299.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027641 Supported "Intracellular and membrane" Other NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 93: Hepatocytes - Bile production & excretion" 10 "HPA027641: " "unprognostic (1.36e-1)" "unprognostic (1.40e-1)" "unprognostic (1.61e-1)" "unprognostic (1.29e-1)" "unprognostic (1.33e-1)" "unprognostic (3.00e-2)" "unprognostic (5.57e-2)" "unprognostic (1.68e-1)" "unprognostic (7.13e-2)" "unprognostic (1.87e-1)" "unprognostic (2.62e-2)" "unprognostic (1.34e-2)" "unprognostic (4.49e-2)" "unprognostic (1.02e-1)" "unprognostic (1.89e-1)" "unprognostic (3.18e-1)" "unprognostic (5.18e-2)" "unprognostic (5.73e-2)" "unprognostic (2.56e-1)" "unprognostic (1.56e-3)" "unprognostic (1.82e-1)" "unprognostic (7.91e-3)" "unprognostic (4.96e-1)" "unprognostic (6.11e-3)" "unprognostic (3.52e-2)" "unprognostic (1.82e-2)" "unprognostic (1.61e-1)" "unprognostic (1.97e-1)" "unprognostic (1.93e-2)" "unprognostic (9.25e-2)" "unprognostic (2.85e-1)" MRPL57 MRP63 ENSG00000173141 "Mitochondrial ribosomal protein L57" Q9BQC6 13 21176658-21179084 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 552.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039779, HPA059370" Supported Supported Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 19: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 37 Mitochondria "HPA039779: , HPA059370: " "unprognostic (8.95e-2)" "unprognostic (5.83e-2)" "unprognostic (1.45e-1)" "unprognostic (1.45e-1)" "unprognostic (1.43e-1)" "unprognostic (3.24e-1)" "unprognostic (4.90e-1)" "unprognostic (6.34e-2)" "unprognostic (2.90e-2)" "potential prognostic favorable (9.17e-4)" "unprognostic (1.20e-2)" "potential prognostic favorable (1.54e-4)" "unprognostic (2.53e-1)" "unprognostic (3.77e-1)" "unprognostic (3.91e-2)" "unprognostic (3.44e-2)" "unprognostic (9.63e-3)" "unprognostic (1.28e-1)" "unprognostic (1.00e-1)" "potential prognostic favorable (3.03e-4)" "unprognostic (3.23e-2)" "unprognostic (2.40e-1)" "unprognostic (2.30e-1)" "unprognostic (2.28e-1)" "unprognostic (3.51e-2)" "unprognostic (1.60e-1)" "unprognostic (1.50e-1)" "unprognostic (1.47e-1)" "unprognostic (2.03e-1)" MRPL58 "DS-1, ICT1" ENSG00000167862 "Mitochondrial ribosomal protein L58" Q14197 17 75012670-75021261 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins, Ribosomal proteins" "Protein biosynthesis" "Hydrolase, Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 92.8;Esophageal suprabasal cells: 97.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003634, HPA076987" Approved Supported "Nucleoplasm,Plasma membrane,Mitochondria" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 27: Breast cancer - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 172 Mitochondria "Nucleoplasm, Plasma membrane" "HPA003634: , HPA076987: " "unprognostic (1.43e-1)" "unprognostic (8.51e-2)" "unprognostic (1.10e-1)" "potential prognostic favorable (1.47e-4)" "unprognostic (1.50e-1)" "unprognostic (1.40e-1)" "unprognostic (2.03e-2)" "potential prognostic unfavorable (6.58e-4)" "unprognostic (2.81e-3)" "unprognostic (6.67e-3)" "unprognostic (3.78e-1)" "unprognostic (4.60e-2)" "potential prognostic unfavorable (9.76e-4)" "unprognostic (2.48e-2)" "potential prognostic unfavorable (4.69e-4)" "unprognostic (1.11e-1)" "unprognostic (3.76e-2)" "unprognostic (2.16e-2)" "unprognostic (1.43e-2)" "unprognostic (1.49e-1)" "unprognostic (1.30e-1)" "unprognostic (1.03e-3)" "unprognostic (3.81e-3)" "unprognostic (2.73e-2)" "unprognostic (3.39e-1)" "unprognostic (6.68e-2)" "unprognostic (2.00e-1)" "unprognostic (1.33e-1)" "unprognostic (2.33e-1)" MRPL9 ENSG00000143436 "Mitochondrial ribosomal protein L9" Q9BYD2 1 151759647-151763496 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 125.5;Extravillous trophoblasts: 143.9;Migrating cytotrophoblasts: 129.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008579, HPA078399" Approved Enhanced Mitochondria NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 27: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 15: Non-specific - Protein processing" 105 Mitochondria "HPA008579: , HPA078399: " "unprognostic (1.32e-1)" "unprognostic (7.68e-2)" "unprognostic (2.69e-1)" "unprognostic (2.29e-2)" "unprognostic (3.91e-1)" "unprognostic (3.14e-1)" "unprognostic (7.18e-2)" "potential prognostic favorable (4.08e-4)" "unprognostic (2.70e-2)" "unprognostic (1.14e-3)" "unprognostic (8.43e-3)" "unprognostic (6.29e-3)" "unprognostic (6.10e-3)" "potential prognostic unfavorable (6.19e-7)" "unprognostic (1.11e-3)" "unprognostic (2.84e-3)" "unprognostic (1.10e-2)" "unprognostic (2.99e-2)" "unprognostic (1.33e-1)" "unprognostic (2.41e-2)" "unprognostic (3.11e-1)" "unprognostic (3.08e-2)" "unprognostic (4.34e-2)" "unprognostic (1.34e-1)" "unprognostic (5.32e-2)" "unprognostic (3.50e-1)" "unprognostic (1.79e-1)" "unprognostic (1.25e-1)" "unprognostic (5.27e-1)" "unprognostic (3.39e-1)" "unprognostic (7.29e-2)" MRPS10 FLJ10567 ENSG00000048544 "Mitochondrial ribosomal protein S10" P82664 6 42206807-42217861 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 621.3;Esophageal suprabasal cells: 192.7;Megakaryocytes: 166.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029133, HPA029134" Supported Approved "Actin filaments,Mitochondria" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 84: Apical squamous epithelium - Cornification" 71 Mitochondria "Actin filaments" "HPA029133: , HPA029134: " "unprognostic (1.32e-2)" "unprognostic (1.14e-2)" "unprognostic (1.31e-1)" "unprognostic (2.05e-1)" "unprognostic (5.45e-2)" "unprognostic (1.28e-1)" "unprognostic (2.45e-1)" "unprognostic (3.82e-2)" "unprognostic (2.10e-2)" "unprognostic (1.43e-3)" "unprognostic (3.61e-3)" "unprognostic (6.95e-2)" "unprognostic (2.49e-1)" "unprognostic (2.58e-3)" "unprognostic (1.20e-2)" "unprognostic (1.67e-3)" "unprognostic (9.62e-3)" "unprognostic (1.41e-2)" "unprognostic (3.69e-1)" "unprognostic (1.31e-1)" "unprognostic (3.61e-2)" "potential prognostic unfavorable (4.87e-4)" "unprognostic (1.66e-1)" "unprognostic (2.56e-1)" "unprognostic (1.15e-1)" "unprognostic (1.02e-1)" "unprognostic (2.77e-2)" "unprognostic (2.31e-1)" "unprognostic (5.17e-1)" "unprognostic (2.66e-2)" "unprognostic (4.48e-1)" MRPS11 "FLJ22512, FLJ23406, HCC-2" ENSG00000181991 "Mitochondrial ribosomal protein S11" P82912 15 88467453-88480776 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 173.9;Esophageal suprabasal cells: 144.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043752, HPA050345" Enhanced Supported Mitochondria NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 35: RS4;11 - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 14 Mitochondria "HPA043752: , HPA050345: " "unprognostic (2.03e-2)" "unprognostic (5.73e-2)" "unprognostic (3.98e-1)" "potential prognostic favorable (7.25e-7)" "unprognostic (3.85e-2)" "unprognostic (1.05e-1)" "unprognostic (2.47e-1)" "potential prognostic favorable (2.90e-4)" "unprognostic (3.09e-1)" "unprognostic (1.85e-1)" "unprognostic (8.16e-3)" "unprognostic (6.27e-2)" "unprognostic (6.00e-3)" "unprognostic (4.04e-2)" "potential prognostic unfavorable (6.52e-6)" "potential prognostic unfavorable (4.29e-4)" "unprognostic (1.72e-1)" "unprognostic (5.64e-3)" "unprognostic (3.35e-1)" "potential prognostic favorable (2.37e-4)" "unprognostic (2.07e-1)" "unprognostic (4.65e-3)" "unprognostic (1.36e-1)" "unprognostic (1.07e-1)" "unprognostic (1.30e-2)" "unprognostic (3.24e-2)" "unprognostic (2.71e-2)" "unprognostic (3.24e-1)" "unprognostic (3.41e-1)" "unprognostic (2.51e-1)" "unprognostic (2.13e-1)" MRPS12 "RPMS12, RPS12, RPSM12" ENSG00000128626 "Mitochondrial ribosomal protein S12" O15235 19 38930944-38933168 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 4.3;Bergmann glia: 5.2;Brain excitatory neurons: 6.4;Brain inhibitory neurons: 6.2;Distal convoluted tubule cells: 10.6;Ependymal cells: 5.3;Loop of henle epithelial cells: 7.6;Microglia: 4.1;Oligodendrocyte progenitor cells: 4.3;Oligodendrocytes: 7.3;Other brain neurons: 8.5;Papillary tip epithelial cells: 9.5;Podocytes: 5.7;Renal collecting duct intercalated cells: 6.3;Renal collecting duct principal cells: 8.3;Renal connecting tubule cells: 4.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046775, HPA050633" Uncertain NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 98: Neurons - Neurotransmission & signaling" 24 "HPA046775: , HPA050633: " "unprognostic (1.11e-1)" "unprognostic (5.14e-2)" "unprognostic (6.81e-2)" "unprognostic (6.62e-2)" "unprognostic (2.54e-2)" "unprognostic (7.82e-2)" "unprognostic (5.13e-2)" "unprognostic (1.23e-1)" "unprognostic (4.20e-2)" "potential prognostic favorable (6.04e-4)" "validated prognostic unfavorable (1.33e-4)" "validated prognostic unfavorable (5.46e-4)" "unprognostic (3.51e-1)" "unprognostic (1.69e-3)" "potential prognostic unfavorable (3.55e-5)" "potential prognostic unfavorable (6.40e-5)" "unprognostic (3.87e-1)" "unprognostic (1.43e-1)" "unprognostic (1.70e-1)" "unprognostic (2.36e-3)" "unprognostic (4.68e-2)" "unprognostic (1.30e-1)" "unprognostic (1.51e-1)" "unprognostic (1.27e-1)" "unprognostic (7.53e-2)" "unprognostic (4.35e-2)" "unprognostic (1.36e-1)" "unprognostic (1.18e-1)" "unprognostic (1.81e-1)" "unprognostic (5.84e-2)" "unprognostic (1.91e-1)" MRPS14 HSMRPS14 ENSG00000120333 "Mitochondrial ribosomal protein S14" O60783 1 175010789-175023425 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal suprabasal cells: 164.1;Gastric progenitor cells: 199.9;Parietal cells: 157.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051087 Uncertain Supported "Nuclear membrane,Mitochondria" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 55: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 97: Non-specific - Cellular respiration" 70 Mitochondria "Nuclear membrane" "HPA051087: " "unprognostic (7.39e-2)" "unprognostic (1.47e-1)" "unprognostic (2.93e-1)" "unprognostic (1.41e-1)" "unprognostic (1.34e-1)" "unprognostic (2.23e-1)" "unprognostic (3.21e-2)" "unprognostic (2.86e-1)" "unprognostic (8.49e-2)" "potential prognostic unfavorable (1.18e-4)" "validated prognostic favorable (2.31e-7)" "validated prognostic favorable (1.13e-4)" "unprognostic (5.81e-3)" "unprognostic (1.37e-1)" "unprognostic (6.23e-2)" "unprognostic (1.98e-2)" "unprognostic (1.23e-1)" "unprognostic (2.16e-1)" "unprognostic (1.52e-1)" "unprognostic (1.14e-1)" "potential prognostic unfavorable (1.58e-4)" "unprognostic (4.64e-3)" "unprognostic (7.42e-2)" "unprognostic (2.34e-1)" "unprognostic (2.32e-1)" "unprognostic (1.80e-1)" "unprognostic (1.13e-2)" "unprognostic (3.93e-2)" "unprognostic (1.17e-1)" "unprognostic (7.60e-2)" "unprognostic (5.57e-2)" MRPS15 FLJ11564 ENSG00000116898 "Mitochondrial ribosomal protein S15" P82914 1 36455718-36464384 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 692.8;Late primary spermatocytes: 1376.8;Late spermatids: 3284.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028100, HPA028134, HPA067137" Supported Supported Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 60 Mitochondria "HPA028100: , HPA028134: , HPA067137: " "unprognostic (7.05e-2)" "unprognostic (8.06e-2)" "unprognostic (9.13e-3)" "unprognostic (3.57e-1)" "unprognostic (1.11e-2)" "unprognostic (2.14e-1)" "unprognostic (4.47e-2)" "unprognostic (8.99e-2)" "unprognostic (1.87e-2)" "unprognostic (1.51e-3)" "potential prognostic unfavorable (2.50e-4)" "unprognostic (4.74e-2)" "unprognostic (1.23e-1)" "validated prognostic unfavorable (2.75e-6)" "validated prognostic unfavorable (1.95e-4)" "unprognostic (2.13e-2)" "unprognostic (6.89e-2)" "unprognostic (4.54e-2)" "unprognostic (4.87e-1)" "unprognostic (2.08e-2)" "unprognostic (8.71e-2)" "unprognostic (1.90e-1)" "unprognostic (1.08e-1)" "unprognostic (2.44e-1)" "unprognostic (8.28e-2)" "unprognostic (5.82e-2)" "unprognostic (3.01e-2)" "unprognostic (1.51e-1)" "unprognostic (2.67e-1)" "unprognostic (4.68e-2)" "unprognostic (9.10e-2)" MRPS16 CGI-132 ENSG00000182180 "Mitochondrial ribosomal protein S16" Q9Y3D3 10 73248843-73252693 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal basal cells: 240.0;Esophageal suprabasal cells: 261.6;Gastric progenitor cells: 261.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in all" "HPA050081, HPA054538" Supported Supported Mitochondria,Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 52: Non-specific - Mitochondria" "Cluster 97: Non-specific - Cellular respiration" 54 Mitochondria Cytosol "HPA050081: , HPA054538: " "unprognostic (2.02e-1)" "unprognostic (3.12e-3)" "unprognostic (3.71e-2)" "unprognostic (1.08e-1)" "unprognostic (2.34e-1)" "unprognostic (3.25e-1)" "unprognostic (3.98e-2)" "potential prognostic favorable (8.07e-6)" "unprognostic (2.63e-2)" "unprognostic (2.90e-2)" "unprognostic (1.52e-2)" "unprognostic (1.27e-2)" "unprognostic (1.51e-1)" "unprognostic (6.10e-3)" "unprognostic (1.66e-3)" "unprognostic (2.04e-3)" "unprognostic (1.70e-1)" "unprognostic (2.61e-2)" "unprognostic (1.55e-1)" "unprognostic (1.40e-2)" "unprognostic (7.81e-2)" "unprognostic (2.94e-1)" "unprognostic (7.76e-2)" "unprognostic (1.33e-1)" "unprognostic (1.37e-1)" "unprognostic (1.97e-2)" "unprognostic (1.07e-1)" "unprognostic (1.03e-2)" "unprognostic (1.44e-1)" "unprognostic (1.04e-1)" "unprognostic (4.54e-2)" MRPS17 "HSPC011, MRP-S17, RPMS17" ENSG00000239789 "Mitochondrial ribosomal protein S17" Q9Y2R5 7 55951877-55956500 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 7.4;Endometrial secretory cells: 8.4;Gastric chief cells: 16.4;Hepatocytes: 10.8;Late primary spermatocytes: 11.5;Mucous neck cells: 7.4;Parietal cells: 26.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047159 Approved NA NA "Cluster 18: Non-specific - Translation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 1: Neurons - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 98 "HPA047159: " "unprognostic (3.47e-1)" "potential prognostic unfavorable (3.22e-4)" "unprognostic (7.96e-2)" "unprognostic (1.74e-1)" "potential prognostic unfavorable (3.92e-4)" "unprognostic (2.26e-1)" "unprognostic (9.91e-2)" "unprognostic (1.92e-3)" "unprognostic (3.14e-3)" "potential prognostic unfavorable (4.60e-4)" "unprognostic (1.50e-2)" "unprognostic (9.79e-2)" "unprognostic (4.70e-1)" "unprognostic (3.27e-3)" "unprognostic (1.19e-3)" "potential prognostic unfavorable (7.99e-4)" "unprognostic (8.96e-2)" "unprognostic (8.39e-2)" "unprognostic (2.61e-2)" "unprognostic (7.89e-2)" "unprognostic (1.79e-1)" "unprognostic (6.68e-2)" "unprognostic (1.02e-1)" "unprognostic (1.40e-1)" "unprognostic (7.37e-2)" "unprognostic (9.33e-2)" "unprognostic (1.35e-1)" "unprognostic (7.50e-2)" "unprognostic (4.50e-2)" "unprognostic (3.90e-1)" "unprognostic (2.28e-2)" MRPS18A "FLJ10548, MRPS18-3" ENSG00000096080 "Mitochondrial ribosomal protein S18A" Q9NVS2 6 43671202-43687791 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 325.2;Esophageal suprabasal cells: 180.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035450, HPA035451" Approved NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 28: Non-specific - Nuclear processes" "Cluster 85: Squamous epithelial cells - Keratinization" 71 "HPA035450: , HPA035451: " "unprognostic (3.12e-2)" "unprognostic (2.53e-3)" "unprognostic (5.19e-2)" "unprognostic (3.32e-1)" "unprognostic (4.17e-2)" "unprognostic (3.28e-1)" "unprognostic (6.21e-2)" "unprognostic (6.09e-1)" "unprognostic (2.12e-2)" "unprognostic (7.39e-2)" "potential prognostic favorable (6.51e-5)" "unprognostic (1.34e-2)" "unprognostic (5.40e-3)" "unprognostic (2.61e-3)" "potential prognostic unfavorable (3.87e-4)" "unprognostic (5.16e-2)" "unprognostic (1.01e-1)" "unprognostic (9.47e-3)" "unprognostic (1.10e-2)" "unprognostic (1.39e-1)" "unprognostic (5.35e-1)" "unprognostic (6.78e-2)" "unprognostic (3.36e-1)" "unprognostic (5.80e-2)" "unprognostic (2.06e-1)" "unprognostic (2.69e-1)" "unprognostic (1.11e-1)" "unprognostic (1.89e-1)" "unprognostic (4.52e-2)" "unprognostic (1.47e-1)" "unprognostic (2.28e-1)" MRPS18B "C6orf14, HSPC183, MRPS18-2, PTD017" ENSG00000204568 "Mitochondrial ribosomal protein S18B" Q9Y676 6 30617840-30626395 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 11.0;Bergmann glia: 14.3;Brain excitatory neurons: 10.7;Brain inhibitory neurons: 10.1;Choroid plexus epithelial cells: 11.7;Distal convoluted tubule cells: 15.8;Ependymal cells: 13.0;Loop of henle epithelial cells: 17.4;Microglia: 12.0;Oligodendrocyte progenitor cells: 10.7;Oligodendrocytes: 20.7;Other brain neurons: 11.4;Papillary tip epithelial cells: 18.4;Podocytes: 10.6;Proximal tubule cells: 14.5;Renal collecting duct intercalated cells: 14.0;Renal collecting duct principal cells: 17.9;Renal connecting tubule cells: 12.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043485, HPA050334" Supported Supported "Cell Junctions,Mitochondria" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 27: Non-specific - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 98: Neurons - Neurotransmission & signaling" 95 Mitochondria "Cell Junctions" "HPA043485: , HPA050334: " "unprognostic (1.73e-2)" "unprognostic (1.12e-2)" "unprognostic (2.12e-1)" "unprognostic (1.70e-1)" "unprognostic (1.31e-1)" "unprognostic (1.39e-1)" "unprognostic (1.98e-2)" "unprognostic (5.96e-2)" "unprognostic (1.24e-1)" "unprognostic (1.59e-1)" "validated prognostic favorable (8.26e-12)" "validated prognostic favorable (2.80e-5)" "potential prognostic favorable (5.43e-4)" "unprognostic (6.28e-2)" "unprognostic (1.94e-2)" "unprognostic (1.02e-1)" "unprognostic (8.25e-2)" "unprognostic (1.65e-1)" "unprognostic (4.78e-1)" "unprognostic (5.04e-2)" "unprognostic (3.54e-1)" "unprognostic (5.49e-2)" "unprognostic (1.09e-1)" "unprognostic (1.07e-1)" "unprognostic (1.35e-2)" "unprognostic (1.29e-1)" "unprognostic (6.02e-2)" "unprognostic (1.12e-1)" "unprognostic (2.90e-1)" "unprognostic (1.67e-1)" "unprognostic (8.27e-2)" MRPS18C "CGI-134, FLJ11146, FLJ22967, MRPS18-1" ENSG00000163319 "Mitochondrial ribosomal protein S18C" Q9Y3D5 4 83455932-83469735 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 301.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050404 Approved NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 97: Non-specific - Cellular respiration" 72 "HPA050404: " "unprognostic (4.63e-2)" "unprognostic (1.04e-3)" "unprognostic (1.33e-1)" "unprognostic (2.21e-2)" "unprognostic (1.10e-2)" "unprognostic (5.85e-2)" "unprognostic (4.98e-2)" "unprognostic (2.34e-2)" "unprognostic (6.80e-3)" "unprognostic (6.18e-3)" "validated prognostic favorable (7.40e-8)" "validated prognostic favorable (1.51e-4)" "unprognostic (1.40e-2)" "unprognostic (2.06e-1)" "unprognostic (1.04e-1)" "potential prognostic unfavorable (6.47e-4)" "unprognostic (2.95e-3)" "unprognostic (2.43e-1)" "unprognostic (2.64e-2)" "unprognostic (1.71e-1)" "unprognostic (2.10e-1)" "unprognostic (5.21e-2)" "unprognostic (8.97e-3)" "unprognostic (8.53e-2)" "unprognostic (6.41e-3)" "unprognostic (1.45e-1)" "unprognostic (2.45e-2)" "unprognostic (4.34e-2)" "unprognostic (2.46e-1)" "unprognostic (5.64e-2)" "unprognostic (2.86e-2)" MRPS2 CGI-91 ENSG00000122140 "Mitochondrial ribosomal protein S2" Q9Y399 9 135499984-135504673 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 105.8;Esophageal basal cells: 108.8;Fallopian secretory cells: 93.6;Migrating cytotrophoblasts: 109.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029487, HPA057261" Approved Supported Mitochondria NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 70: Non-specific - Protein processing" "Cluster 23: Choroid plexus - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 51: Secretory epithelial cells - Mixed function" 107 Mitochondria "HPA029487: , HPA057261: " "unprognostic (9.49e-3)" "potential prognostic unfavorable (4.24e-4)" "unprognostic (9.21e-2)" "unprognostic (3.27e-2)" "unprognostic (1.10e-1)" "unprognostic (1.85e-1)" "unprognostic (4.46e-1)" "unprognostic (1.64e-2)" "unprognostic (8.70e-2)" "unprognostic (2.60e-1)" "potential prognostic favorable (3.35e-7)" "unprognostic (1.84e-3)" "potential prognostic favorable (4.54e-4)" "unprognostic (8.09e-2)" "potential prognostic unfavorable (3.69e-4)" "unprognostic (3.85e-3)" "potential prognostic unfavorable (3.91e-4)" "unprognostic (7.00e-2)" "unprognostic (3.84e-2)" "unprognostic (4.86e-2)" "unprognostic (2.38e-1)" "unprognostic (6.87e-2)" "unprognostic (1.26e-1)" "unprognostic (1.37e-2)" "unprognostic (5.76e-2)" "unprognostic (2.14e-1)" "unprognostic (1.92e-1)" "unprognostic (2.13e-2)" "unprognostic (1.05e-1)" "unprognostic (8.93e-3)" "unprognostic (1.22e-1)" MRPS21 ENSG00000266472 "Mitochondrial ribosomal protein S21" P82921 1 150293861-150308979 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 851.5;Gastric progenitor cells: 581.9;Late primary spermatocytes: 712.8;Late spermatids: 922.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078289 Supported Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 97: Non-specific - Cellular respiration" 30 Mitochondria "HPA078289: " "unprognostic (1.58e-1)" "unprognostic (1.74e-1)" "unprognostic (6.94e-2)" "unprognostic (4.52e-2)" "unprognostic (1.34e-1)" "unprognostic (1.66e-1)" "unprognostic (1.59e-2)" "unprognostic (1.27e-1)" "unprognostic (3.23e-1)" "unprognostic (2.19e-3)" "unprognostic (4.61e-2)" "unprognostic (2.26e-1)" "potential prognostic unfavorable (1.64e-4)" "unprognostic (1.37e-1)" "unprognostic (2.77e-1)" "unprognostic (2.47e-1)" "unprognostic (3.42e-3)" "unprognostic (3.09e-1)" "unprognostic (7.98e-2)" "unprognostic (4.67e-2)" "unprognostic (2.85e-2)" "unprognostic (2.48e-1)" "unprognostic (4.30e-2)" "unprognostic (1.36e-2)" "unprognostic (1.99e-1)" "unprognostic (2.84e-2)" "unprognostic (9.01e-2)" "unprognostic (2.22e-1)" MRPS22 "C3orf5, GIBT, GK002, MRP-S22" ENSG00000175110 "Mitochondrial ribosomal protein S22" P82650 3 139005806-139360497 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 235.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006083, HPA007830" Enhanced Supported Mitochondria NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 97: Non-specific - Cellular respiration" 79 Mitochondria "HPA006083: , HPA007830: " "unprognostic (8.13e-3)" "unprognostic (1.76e-2)" "unprognostic (3.28e-2)" "unprognostic (1.30e-1)" "unprognostic (1.22e-1)" "unprognostic (1.44e-1)" "unprognostic (8.69e-2)" "unprognostic (6.44e-3)" "potential prognostic unfavorable (9.81e-4)" "unprognostic (1.52e-3)" "potential prognostic favorable (1.58e-5)" "unprognostic (5.12e-2)" "unprognostic (5.06e-2)" "unprognostic (4.70e-3)" "unprognostic (5.36e-3)" "unprognostic (1.00e-3)" "potential prognostic unfavorable (4.17e-4)" "unprognostic (5.90e-2)" "unprognostic (2.81e-1)" "unprognostic (3.21e-2)" "unprognostic (1.81e-1)" "potential prognostic unfavorable (2.33e-6)" "unprognostic (1.69e-2)" "unprognostic (1.73e-2)" "unprognostic (2.76e-2)" "unprognostic (3.00e-2)" "unprognostic (1.64e-2)" "unprognostic (1.69e-1)" "unprognostic (1.38e-1)" "unprognostic (2.37e-1)" "unprognostic (2.97e-1)" MRPS23 "CGI-138, HSPC329, MRP-S23" ENSG00000181610 "Mitochondrial ribosomal protein S23" Q9Y3D9 17 57834781-57850056 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Prostate - Prostate glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023453 Supported Supported "Nuclear membrane,Mitochondria" No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 27: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 101 Mitochondria "Nuclear membrane" "HPA023453: " "unprognostic (1.81e-1)" "unprognostic (1.40e-3)" "unprognostic (1.73e-2)" "unprognostic (1.53e-1)" "unprognostic (1.29e-2)" "unprognostic (7.68e-2)" "unprognostic (1.66e-1)" "unprognostic (6.08e-1)" "potential prognostic unfavorable (3.36e-5)" "unprognostic (1.46e-2)" "unprognostic (2.76e-3)" "unprognostic (2.62e-3)" "unprognostic (1.08e-1)" "validated prognostic unfavorable (1.98e-5)" "validated prognostic unfavorable (3.98e-7)" "unprognostic (1.58e-1)" "unprognostic (1.54e-2)" "unprognostic (3.14e-1)" "unprognostic (2.05e-2)" "unprognostic (9.72e-3)" "unprognostic (1.67e-1)" "unprognostic (1.87e-2)" "unprognostic (8.79e-2)" "unprognostic (2.04e-1)" "unprognostic (4.35e-2)" "potential prognostic favorable (6.63e-4)" "unprognostic (2.18e-1)" "unprognostic (2.55e-1)" "unprognostic (1.45e-1)" "unprognostic (1.21e-1)" "unprognostic (4.44e-2)" MRPS24 "HSPC335, MRP-S24" ENSG00000062582 "Mitochondrial ribosomal protein S24" Q96EL2 7 43866558-43869893 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bergmann glia: 11.1;Brain excitatory neurons: 19.9;Brain inhibitory neurons: 17.7;Cholangiocytes: 9.2;Endometrial secretory cells: 13.3;Ependymal cells: 15.2;Hepatocytes: 19.2;Oligodendrocyte progenitor cells: 11.0;Oligodendrocytes: 14.9;Other brain neurons: 25.3;Parietal cells: 17.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073947 Approved NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 14: Neurons - Synaptic function" "Cluster 67: Non-specific - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" 127 "HPA073947: " "potential prognostic unfavorable (4.79e-4)" "unprognostic (1.99e-1)" "unprognostic (6.43e-2)" "unprognostic (2.68e-1)" "unprognostic (1.42e-2)" "unprognostic (1.57e-2)" "unprognostic (6.13e-3)" "unprognostic (4.04e-1)" "unprognostic (1.90e-2)" "potential prognostic unfavorable (9.90e-9)" "unprognostic (2.26e-2)" "unprognostic (2.27e-2)" "unprognostic (9.41e-2)" "unprognostic (6.37e-3)" "potential prognostic unfavorable (4.55e-9)" "validated prognostic unfavorable (1.87e-5)" "validated prognostic unfavorable (6.26e-4)" "unprognostic (1.31e-2)" "unprognostic (3.11e-1)" "unprognostic (9.48e-2)" "unprognostic (1.35e-1)" "unprognostic (1.90e-1)" "unprognostic (1.44e-1)" "unprognostic (7.83e-2)" "unprognostic (2.51e-1)" "unprognostic (1.42e-1)" "unprognostic (3.58e-1)" "unprognostic (2.18e-1)" "unprognostic (3.70e-1)" "unprognostic (1.69e-1)" "unprognostic (3.23e-1)" MRPS25 "DKFZp313H0817, FLJ00023, MRP-S25, RPMS25" ENSG00000131368 "Mitochondrial ribosomal protein S25" P82663 3 15009611-15065339 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 142.4;Epicardial cells: 216.0;Late spermatids: 141.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043490 Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 108 Mitochondria "HPA043490: " "unprognostic (1.27e-1)" "unprognostic (3.95e-3)" "unprognostic (6.24e-3)" "unprognostic (1.28e-1)" "unprognostic (5.92e-2)" "unprognostic (1.36e-1)" "unprognostic (7.77e-2)" "unprognostic (2.03e-2)" "unprognostic (9.21e-2)" "unprognostic (2.70e-3)" "unprognostic (1.58e-1)" "unprognostic (1.17e-1)" "potential prognostic favorable (1.16e-6)" "unprognostic (3.50e-2)" "unprognostic (2.62e-3)" "unprognostic (1.62e-1)" "unprognostic (1.01e-1)" "unprognostic (1.62e-2)" "unprognostic (1.23e-1)" "unprognostic (8.02e-2)" "unprognostic (1.25e-1)" "unprognostic (1.30e-1)" "unprognostic (2.21e-1)" "unprognostic (2.05e-3)" "unprognostic (4.07e-2)" "unprognostic (8.74e-3)" "unprognostic (3.92e-1)" "unprognostic (6.58e-2)" "unprognostic (1.80e-1)" "unprognostic (1.68e-1)" "unprognostic (3.40e-1)" MRPS26 "C20orf193, dJ534B8.3, MRP-S13, MRP-S26, RPMS13" ENSG00000125901 "Mitochondrial ribosomal protein S26" Q9BYN8 20 3046052-3048250 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 223.6;Esophageal basal cells: 244.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045472, HPA054610" Supported Supported Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 70: Non-specific - Protein processing" "Cluster 45: Non-specific - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 97: Non-specific - Cellular respiration" 160 Mitochondria "HPA045472: , HPA054610: " "unprognostic (2.97e-1)" "unprognostic (2.88e-1)" "unprognostic (3.49e-2)" "unprognostic (7.66e-2)" "unprognostic (1.94e-1)" "unprognostic (9.88e-2)" "unprognostic (5.96e-2)" "unprognostic (1.18e-1)" "unprognostic (4.77e-1)" "unprognostic (2.11e-1)" "unprognostic (4.91e-2)" "unprognostic (6.94e-2)" "unprognostic (2.50e-2)" "unprognostic (2.08e-2)" "unprognostic (1.08e-3)" "unprognostic (2.95e-1)" "unprognostic (2.90e-1)" "unprognostic (2.44e-1)" "unprognostic (2.56e-2)" "unprognostic (1.22e-1)" "unprognostic (1.09e-1)" "unprognostic (1.21e-3)" "unprognostic (1.53e-1)" "unprognostic (1.90e-1)" "unprognostic (1.86e-1)" "unprognostic (1.08e-1)" "unprognostic (7.50e-2)" "unprognostic (2.33e-1)" "unprognostic (9.87e-2)" "unprognostic (5.38e-2)" "unprognostic (3.19e-2)" MRPS27 KIAA0264 ENSG00000113048 "Mitochondrial ribosomal protein S27" Q92552 5 72214953-72321717 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Translation regulation" "Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding, tRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071751 Approved Supported Nucleoli,Mitochondria NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 122 Mitochondria Nucleoli "HPA071751: " "unprognostic (6.02e-3)" "unprognostic (1.45e-1)" "unprognostic (7.58e-2)" "unprognostic (4.73e-2)" "unprognostic (4.70e-2)" "unprognostic (2.58e-2)" "unprognostic (2.88e-2)" "unprognostic (3.61e-1)" "unprognostic (1.16e-1)" "unprognostic (2.88e-3)" "potential prognostic favorable (1.71e-4)" "unprognostic (5.65e-3)" "unprognostic (1.74e-1)" "unprognostic (1.65e-2)" "unprognostic (1.71e-2)" "unprognostic (1.31e-2)" "unprognostic (3.39e-2)" "unprognostic (4.04e-2)" "unprognostic (2.82e-1)" "unprognostic (8.04e-3)" "unprognostic (1.50e-3)" "unprognostic (6.49e-2)" "unprognostic (3.25e-1)" "unprognostic (3.14e-1)" "unprognostic (1.20e-2)" "unprognostic (3.48e-1)" "unprognostic (5.61e-2)" "unprognostic (6.44e-2)" "unprognostic (5.09e-2)" "unprognostic (1.96e-2)" "unprognostic (2.36e-2)" MRPS28 "HSPC007, MRP-S28, MRPS35" ENSG00000147586 "Mitochondrial ribosomal protein S28" Q9Y2Q9 8 79918717-80030289 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 75.3;Extravillous trophoblasts: 69.3;Migrating cytotrophoblasts: 68.7;Oocytes: 96.7;Parietal cells: 72.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Stomach - Mitotic cells (Stomach), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027202 Approved Supported Mitochondria NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 76: Non-specific - Metabolism" "Cluster 55: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 39 Mitochondria "HPA027202: " "unprognostic (9.88e-3)" "potential prognostic unfavorable (6.58e-4)" "unprognostic (3.85e-1)" "unprognostic (3.10e-1)" "unprognostic (5.65e-3)" "unprognostic (3.08e-2)" "unprognostic (6.53e-2)" "unprognostic (1.04e-2)" "potential prognostic unfavorable (2.23e-4)" "potential prognostic unfavorable (8.54e-4)" "potential prognostic favorable (2.13e-5)" "unprognostic (1.32e-1)" "unprognostic (4.59e-2)" "unprognostic (6.04e-2)" "unprognostic (1.24e-1)" "potential prognostic unfavorable (8.08e-4)" "unprognostic (2.48e-1)" "unprognostic (1.26e-1)" "unprognostic (1.06e-1)" "unprognostic (4.68e-2)" "unprognostic (9.66e-3)" "unprognostic (7.83e-2)" "unprognostic (1.65e-2)" "unprognostic (6.49e-2)" "unprognostic (2.38e-2)" "unprognostic (9.36e-2)" "unprognostic (4.53e-2)" "unprognostic (2.09e-1)" "unprognostic (2.92e-1)" "unprognostic (1.52e-1)" "unprognostic (9.24e-2)" MRPS30 "PAP, PDCD9" ENSG00000112996 "Mitochondrial ribosomal protein S30" Q9NP92 5 44808947-44820428 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 135.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018686, HPA021149" Approved NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 53: Neurons - Mixed function" "Cluster 29: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 93 "HPA018686: , HPA021149: " "unprognostic (5.82e-2)" "unprognostic (3.07e-1)" "unprognostic (2.90e-1)" "unprognostic (9.51e-2)" "unprognostic (1.58e-1)" "unprognostic (5.76e-2)" "unprognostic (1.02e-1)" "unprognostic (1.59e-1)" "unprognostic (1.99e-2)" "unprognostic (5.88e-3)" "potential prognostic favorable (9.82e-7)" "unprognostic (3.14e-2)" "unprognostic (9.65e-2)" "potential prognostic unfavorable (2.09e-6)" "unprognostic (8.23e-3)" "unprognostic (3.43e-2)" "potential prognostic unfavorable (3.92e-4)" "unprognostic (9.52e-2)" "unprognostic (3.92e-2)" "unprognostic (3.89e-1)" "unprognostic (1.89e-1)" "unprognostic (4.63e-2)" "unprognostic (2.01e-1)" "unprognostic (4.68e-2)" "unprognostic (1.07e-2)" "unprognostic (5.80e-2)" "unprognostic (8.30e-3)" "unprognostic (1.82e-2)" "unprognostic (2.57e-1)" "unprognostic (2.07e-3)" "unprognostic (3.08e-1)" MRPS31 IMOGN38 ENSG00000102738 "Mitochondrial ribosomal protein S31" Q92665 13 40729128-40771190 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 207.2;Respiratory ciliated cells: 446.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039083, HPA046344" Uncertain Supported Nucleoli,Mitochondria NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 107: Ciliated cells - Cilia assembly & function" 98 Mitochondria Nucleoli "HPA039083: , HPA046344: " "unprognostic (2.07e-1)" "unprognostic (1.60e-1)" "unprognostic (1.81e-1)" "unprognostic (9.13e-2)" "unprognostic (2.91e-2)" "unprognostic (1.02e-1)" "unprognostic (4.26e-1)" "unprognostic (2.34e-2)" "unprognostic (4.14e-2)" "unprognostic (3.90e-2)" "potential prognostic favorable (2.68e-9)" "unprognostic (1.21e-2)" "unprognostic (2.37e-2)" "unprognostic (1.54e-2)" "unprognostic (1.77e-1)" "unprognostic (2.64e-2)" "unprognostic (2.12e-2)" "unprognostic (2.29e-1)" "unprognostic (3.84e-1)" "unprognostic (2.24e-2)" "unprognostic (1.11e-3)" "unprognostic (6.16e-2)" "potential prognostic unfavorable (8.15e-4)" "unprognostic (7.86e-2)" "unprognostic (6.42e-2)" "unprognostic (2.94e-2)" "unprognostic (4.17e-2)" "unprognostic (1.14e-1)" "unprognostic (1.80e-1)" "unprognostic (1.22e-2)" "unprognostic (3.38e-1)" MRPS33 CGI-139 ENSG00000090263 "Mitochondrial ribosomal protein S33" Q9Y291 7 141002610-141015228 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 249.8;Late primary spermatocytes: 302.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030425 Uncertain NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 39: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 45 "HPA030425: " "unprognostic (1.21e-1)" "unprognostic (5.84e-2)" "unprognostic (8.96e-2)" "unprognostic (7.80e-2)" "unprognostic (4.43e-1)" "unprognostic (3.09e-1)" "potential prognostic unfavorable (5.62e-5)" "unprognostic (5.01e-3)" "unprognostic (2.23e-2)" "unprognostic (2.12e-3)" "unprognostic (2.90e-3)" "unprognostic (7.83e-2)" "unprognostic (3.44e-2)" "unprognostic (3.81e-2)" "unprognostic (6.86e-3)" "unprognostic (2.41e-2)" "unprognostic (1.17e-1)" "unprognostic (4.84e-3)" "unprognostic (3.27e-1)" "potential prognostic favorable (2.64e-6)" "unprognostic (4.87e-2)" "unprognostic (1.16e-1)" "unprognostic (2.05e-1)" "unprognostic (5.08e-1)" "unprognostic (1.77e-1)" "unprognostic (3.34e-2)" "unprognostic (4.40e-3)" "unprognostic (5.57e-2)" "unprognostic (7.13e-2)" "unprognostic (2.32e-2)" "unprognostic (9.53e-2)" MRPS34 "MGC2616, MRP-S12" ENSG00000074071 "Mitochondrial ribosomal protein S34" P82930 16 1771890-1773150 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 406.8;Esophageal suprabasal cells: 340.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042112 Supported Supported Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 24: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 107 Mitochondria "HPA042112: " "unprognostic (3.83e-1)" "unprognostic (2.42e-1)" "unprognostic (2.47e-1)" "unprognostic (1.02e-1)" "unprognostic (3.92e-3)" "unprognostic (2.02e-1)" "unprognostic (8.80e-2)" "unprognostic (7.72e-2)" "unprognostic (1.53e-1)" "unprognostic (2.86e-1)" "unprognostic (1.33e-1)" "unprognostic (9.02e-2)" "unprognostic (1.99e-1)" "unprognostic (2.14e-2)" "unprognostic (2.38e-3)" "unprognostic (3.22e-3)" "unprognostic (3.87e-2)" "unprognostic (1.07e-2)" "unprognostic (2.00e-1)" "unprognostic (7.13e-2)" "unprognostic (2.22e-2)" "unprognostic (1.85e-1)" "unprognostic (3.00e-1)" "unprognostic (5.95e-3)" "unprognostic (5.81e-2)" "unprognostic (6.43e-2)" "unprognostic (1.29e-1)" "unprognostic (2.75e-2)" "unprognostic (1.52e-1)" "unprognostic (1.06e-1)" "unprognostic (1.94e-1)" MRPS35 "MDS023, MRPS28" ENSG00000061794 "Mitochondrial ribosomal protein S35" P82673 12 27710822-27756295 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" HPA038513 Supported Supported "Mitochondria,Cytosol,Connecting piece" No No "Cluster 33: Non-specific - ATP binding" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 97: Non-specific - Cellular respiration" 87 Mitochondria "Cytosol, Connecting piece" "HPA038513: " "unprognostic (1.30e-1)" "unprognostic (1.14e-3)" "potential prognostic unfavorable (2.32e-4)" "unprognostic (8.11e-2)" "unprognostic (1.51e-1)" "unprognostic (3.89e-1)" "unprognostic (1.67e-2)" "unprognostic (3.38e-1)" "unprognostic (4.57e-2)" "potential prognostic unfavorable (3.01e-4)" "potential prognostic favorable (7.24e-6)" "unprognostic (1.84e-1)" "unprognostic (1.14e-1)" "validated prognostic unfavorable (5.33e-5)" "validated prognostic unfavorable (5.82e-5)" "potential prognostic unfavorable (1.11e-4)" "unprognostic (3.45e-3)" "unprognostic (1.07e-2)" "unprognostic (2.24e-1)" "unprognostic (3.49e-1)" "unprognostic (2.25e-1)" "unprognostic (1.60e-2)" "unprognostic (3.04e-2)" "unprognostic (1.01e-1)" "potential prognostic favorable (9.43e-4)" "unprognostic (7.16e-2)" "unprognostic (3.61e-2)" "unprognostic (7.92e-2)" "unprognostic (1.44e-1)" "unprognostic (7.60e-2)" "unprognostic (9.86e-2)" MRPS36 "DC47, MRP-S36" ENSG00000134056 "Mitochondrial ribosomal protein S36" P82909 5 69217760-69230158 "Predicted intracellular proteins" "Tricarboxylic acid cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 285.9;Parietal cells: 378.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035802, HPA056795" Supported Enhanced Mitochondria NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cellular respiration" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 97: Non-specific - Cellular respiration" 16 Mitochondria "HPA035802: , HPA056795: " "unprognostic (1.77e-1)" "unprognostic (6.37e-2)" "unprognostic (1.50e-2)" "unprognostic (1.09e-2)" "unprognostic (8.53e-3)" "unprognostic (3.26e-2)" "unprognostic (3.82e-1)" "unprognostic (2.96e-1)" "unprognostic (1.34e-2)" "unprognostic (1.12e-1)" "potential prognostic favorable (2.98e-9)" "unprognostic (4.02e-2)" "unprognostic (6.33e-2)" "unprognostic (1.34e-1)" "potential prognostic unfavorable (6.13e-4)" "unprognostic (1.20e-1)" "unprognostic (2.05e-1)" "unprognostic (1.99e-1)" "unprognostic (1.20e-1)" "unprognostic (1.43e-2)" "unprognostic (6.09e-3)" "unprognostic (2.16e-2)" "unprognostic (4.58e-3)" "unprognostic (8.54e-2)" "unprognostic (3.03e-1)" "unprognostic (2.41e-2)" "unprognostic (2.16e-1)" "unprognostic (2.08e-2)" "unprognostic (3.19e-1)" "unprognostic (3.84e-2)" "unprognostic (1.40e-1)" MRPS5 "MRP-S5, S5mt" ENSG00000144029 "Mitochondrial ribosomal protein S5" P82675 2 95085369-95122006 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 71.6;Bergmann glia: 72.5;Brain excitatory neurons: 83.5;Brain inhibitory neurons: 73.0;Choroid plexus epithelial cells: 69.9;Distal convoluted tubule cells: 83.6;Oligodendrocyte progenitor cells: 69.7;Oligodendrocytes: 84.5;Other brain neurons: 74.9;Renal collecting duct intercalated cells: 107.9;Renal connecting tubule cells: 68.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055765 Approved Supported "Midbody,Primary cilium,Mitochondria" Yes No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 76: Non-specific - Metabolism" "Cluster 37: Neurons - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 102: Non-specific - Mixed function" 73 Mitochondria "Midbody, Primary cilium" "HPA055765: " "unprognostic (5.45e-3)" "unprognostic (4.52e-3)" "unprognostic (6.05e-3)" "unprognostic (1.64e-1)" "unprognostic (1.82e-1)" "unprognostic (2.01e-1)" "unprognostic (3.39e-2)" "unprognostic (3.42e-3)" "potential prognostic unfavorable (5.49e-7)" "unprognostic (1.57e-2)" "potential prognostic favorable (9.41e-6)" "unprognostic (1.67e-2)" "unprognostic (2.90e-1)" "validated prognostic unfavorable (8.43e-5)" "validated prognostic unfavorable (1.10e-6)" "potential prognostic unfavorable (2.70e-4)" "unprognostic (7.85e-2)" "unprognostic (4.77e-3)" "unprognostic (1.65e-1)" "unprognostic (1.45e-2)" "unprognostic (1.44e-1)" "unprognostic (8.53e-2)" "unprognostic (4.74e-3)" "unprognostic (1.50e-2)" "unprognostic (1.66e-1)" "unprognostic (3.73e-1)" "unprognostic (2.68e-1)" "unprognostic (1.89e-1)" "unprognostic (5.30e-1)" "unprognostic (1.79e-2)" "unprognostic (1.16e-1)" MRPS6 "C21orf101, MRP-S6, RPMS6" ENSG00000243927 "Mitochondrial ribosomal protein S6" P82932 21 34073224-34143034 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 320.1;kidney: 308.2" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 340.5;Loop of henle epithelial cells: 485.4;Papillary tip epithelial cells: 132.4;Podocytes: 84.9;Renal collecting duct intercalated cells: 236.4;Renal collecting duct principal cells: 290.5;Renal connecting tubule cells: 109.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007861, HPA008163, HPA049676" Supported Supported Mitochondria NA NA "Cluster 1: T-cells - Unknown function" "Cluster 72: Kidney - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 50 Mitochondria "HPA007861: , HPA008163: , HPA049676: " "unprognostic (1.32e-1)" "unprognostic (2.38e-3)" "unprognostic (4.10e-2)" "unprognostic (2.92e-2)" "unprognostic (3.26e-2)" "unprognostic (2.28e-1)" "unprognostic (5.54e-3)" "unprognostic (1.84e-3)" "unprognostic (1.09e-2)" "unprognostic (3.67e-2)" "unprognostic (6.81e-3)" "unprognostic (4.54e-2)" "unprognostic (2.98e-1)" "potential prognostic unfavorable (1.65e-4)" "unprognostic (6.69e-2)" "unprognostic (5.12e-2)" "potential prognostic unfavorable (2.83e-4)" "unprognostic (2.04e-1)" "unprognostic (9.13e-2)" "unprognostic (4.52e-2)" "unprognostic (4.64e-1)" "unprognostic (1.51e-3)" "unprognostic (8.21e-3)" "unprognostic (1.53e-1)" "unprognostic (6.15e-2)" "unprognostic (3.76e-2)" "unprognostic (7.79e-2)" "unprognostic (4.47e-2)" "unprognostic (2.14e-2)" "unprognostic (3.37e-1)" "unprognostic (1.52e-1)" MRPS7 "MRP-S, RP-S7, RPMS7" ENSG00000125445 "Mitochondrial ribosomal protein S7" Q9Y2R9 17 75261674-75266376 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 231.3;Esophageal suprabasal cells: 240.0;Late spermatids: 846.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022522, HPA023007" Supported Approved Mitochondria No No "Cluster 13: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 27: Breast cancer - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 94 Mitochondria "HPA022522: , HPA023007: " "unprognostic (1.28e-1)" "unprognostic (2.61e-2)" "unprognostic (1.82e-1)" "unprognostic (8.64e-2)" "potential prognostic favorable (4.62e-4)" "unprognostic (2.79e-1)" "unprognostic (4.23e-2)" "unprognostic (1.98e-1)" "potential prognostic unfavorable (1.70e-4)" "unprognostic (5.77e-2)" "potential prognostic favorable (6.89e-4)" "unprognostic (8.23e-3)" "unprognostic (1.56e-2)" "validated prognostic unfavorable (7.79e-4)" "validated prognostic unfavorable (1.92e-5)" "unprognostic (9.65e-3)" "unprognostic (1.29e-1)" "unprognostic (9.03e-2)" "unprognostic (6.70e-3)" "unprognostic (2.80e-2)" "unprognostic (4.70e-2)" "unprognostic (4.51e-2)" "unprognostic (1.84e-1)" "unprognostic (1.05e-3)" "unprognostic (3.02e-2)" "unprognostic (2.01e-1)" "unprognostic (1.44e-1)" "unprognostic (2.00e-1)" "unprognostic (1.41e-1)" "unprognostic (4.47e-1)" "unprognostic (1.18e-1)" MRPS9 "MRP-S9, RPMS9, S9mt" ENSG00000135972 "Mitochondrial ribosomal protein S9" P82933 2 105038069-105099960 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 218.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Minor Salivary Gland - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043476, HPA048479" Supported Supported Mitochondria No No "Cluster 33: Non-specific - ATP binding" "Cluster 52: Non-specific - Cellular respiration" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 111 Mitochondria "HPA043476: , HPA048479: " "unprognostic (5.49e-3)" "potential prognostic unfavorable (2.18e-4)" "unprognostic (1.35e-1)" "unprognostic (8.78e-2)" "unprognostic (2.17e-1)" "unprognostic (4.31e-2)" "unprognostic (2.30e-1)" "unprognostic (1.46e-2)" "unprognostic (4.71e-3)" "unprognostic (1.06e-2)" "potential prognostic favorable (2.04e-5)" "unprognostic (1.36e-3)" "unprognostic (3.17e-1)" "validated prognostic unfavorable (1.91e-7)" "validated prognostic unfavorable (1.20e-4)" "unprognostic (6.14e-3)" "unprognostic (5.82e-2)" "unprognostic (1.53e-2)" "unprognostic (1.12e-2)" "unprognostic (1.98e-1)" "unprognostic (4.47e-2)" "unprognostic (3.92e-1)" "unprognostic (1.69e-1)" "unprognostic (1.38e-1)" "unprognostic (9.47e-2)" "unprognostic (1.60e-1)" "unprognostic (2.94e-1)" "unprognostic (3.14e-1)" "unprognostic (4.67e-1)" "unprognostic (8.10e-2)" "unprognostic (1.94e-1)" MRRF RRF ENSG00000148187 "Mitochondrial ribosome recycling factor" Q96E11 9 122264603-122331337 "Predicted intracellular proteins" "Protein biosynthesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 295.4;Late spermatids: 280.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047177, HPA049987" Supported Approved "Microtubules,Cytokinetic bridge" Yes No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 44: Non-specific - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 20 "Microtubules, Cytokinetic bridge" "HPA047177: , HPA049987: " "unprognostic (2.78e-1)" "potential prognostic unfavorable (2.00e-4)" "unprognostic (3.73e-1)" "unprognostic (5.06e-2)" "unprognostic (2.64e-1)" "unprognostic (2.10e-2)" "unprognostic (8.11e-2)" "unprognostic (9.94e-3)" "unprognostic (1.55e-2)" "unprognostic (3.90e-2)" "potential prognostic favorable (7.47e-9)" "unprognostic (1.06e-2)" "unprognostic (1.08e-1)" "unprognostic (5.80e-2)" "unprognostic (8.77e-2)" "unprognostic (9.10e-3)" "unprognostic (4.27e-2)" "unprognostic (1.65e-1)" "unprognostic (2.89e-1)" "unprognostic (3.61e-2)" "unprognostic (3.11e-2)" "unprognostic (4.74e-3)" "unprognostic (2.72e-2)" "unprognostic (2.70e-1)" "unprognostic (1.91e-2)" "unprognostic (3.49e-2)" "unprognostic (8.46e-2)" "unprognostic (1.96e-1)" "unprognostic (1.58e-1)" "unprognostic (7.12e-2)" "unprognostic (1.71e-1)" MRS2 MRS2L ENSG00000124532 "Magnesium transporter MRS2" Q9HD23 6 24402908-24426194 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 114.7;Parietal cells: 104.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017642 Uncertain NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 2: Neurons - Nucleosome" "Cluster 28: Non-specific - Nuclear processes" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 1 "HPA017642: " "unprognostic (1.02e-1)" "unprognostic (1.24e-2)" "unprognostic (1.13e-1)" "unprognostic (2.52e-2)" "unprognostic (3.03e-2)" "unprognostic (8.63e-3)" "unprognostic (1.15e-1)" "unprognostic (1.20e-1)" "unprognostic (1.14e-1)" "unprognostic (3.34e-3)" "potential prognostic favorable (1.20e-5)" "unprognostic (2.73e-2)" "unprognostic (2.61e-1)" "unprognostic (2.01e-2)" "unprognostic (4.67e-2)" "unprognostic (5.14e-2)" "unprognostic (9.24e-2)" "unprognostic (2.40e-1)" "unprognostic (9.42e-2)" "potential prognostic favorable (5.35e-5)" "unprognostic (2.65e-2)" "unprognostic (4.92e-1)" "unprognostic (1.12e-1)" "unprognostic (1.63e-2)" "unprognostic (1.65e-3)" "unprognostic (2.81e-1)" "unprognostic (4.33e-3)" "unprognostic (2.57e-1)" "unprognostic (5.60e-2)" "potential prognostic unfavorable (2.90e-5)" "unprognostic (1.35e-1)" MRTFA "BSAC, KIAA1438, MAL, MKL, MKL1, MRTF-A" ENSG00000196588 "Myocardin related transcription factor A" Q969V6 22 40410281-40636719 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Actin-binding "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 694.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 189.9" "Group enriched" "Detected in all" 5 "dendritic cells: 93.0;granulocytes: 189.9;monocytes: 58.9" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Breast - Breast myoepithelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030782 Approved Supported "Nucleoplasm,Nuclear membrane,Cytosol" No No "Cluster 29: Non-specific - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 51: Neurons - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 103: Non-specific - Basic cellular processes" 11 Nucleoplasm "Nuclear membrane, Cytosol" "HPA030782: " "unprognostic (1.23e-2)" "unprognostic (1.49e-2)" "unprognostic (1.37e-2)" "unprognostic (3.83e-1)" "unprognostic (3.05e-2)" "unprognostic (7.16e-2)" "unprognostic (5.46e-2)" "unprognostic (2.51e-1)" "unprognostic (9.92e-2)" "unprognostic (4.11e-3)" "unprognostic (1.18e-1)" "unprognostic (2.66e-1)" "unprognostic (5.83e-3)" "unprognostic (8.73e-3)" "unprognostic (7.99e-2)" "unprognostic (1.27e-1)" "unprognostic (2.69e-2)" "unprognostic (3.48e-3)" "unprognostic (1.43e-1)" "unprognostic (8.92e-2)" "unprognostic (3.34e-2)" "unprognostic (1.46e-1)" "unprognostic (8.17e-2)" "potential prognostic favorable (6.13e-4)" "unprognostic (3.47e-1)" "unprognostic (5.36e-2)" "unprognostic (2.16e-1)" "unprognostic (3.28e-3)" "unprognostic (1.13e-1)" MRTFB "FLJ31823, MKL2, MRTF-B" ENSG00000186260 "Myocardin related transcription factor B" Q9ULH7 16 14071319-14266773 "Disease related genes, Predicted intracellular proteins" "Differentiation, Myogenesis, Transcription, Transcription regulation" "Activator, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pituitary stem cells: 482.5;Respiratory basal cells: 600.2;Respiratory secretory cells: 493.0;Vascular endothelial cells: 602.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Colon - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Spleen - Endothelial cells, Stomach - Endothelial cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011286 Enhanced Supported "Nuclear speckles" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 51: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 5 "Nuclear speckles" "HPA011286: " "unprognostic (2.25e-2)" "unprognostic (1.11e-1)" "unprognostic (1.41e-2)" "unprognostic (2.35e-1)" "unprognostic (1.20e-1)" "unprognostic (1.30e-1)" "unprognostic (4.26e-2)" "unprognostic (7.99e-3)" "unprognostic (6.03e-2)" "potential prognostic favorable (2.78e-6)" "unprognostic (1.25e-2)" "unprognostic (2.46e-1)" "unprognostic (2.01e-1)" "unprognostic (1.77e-1)" "unprognostic (1.66e-1)" "unprognostic (1.20e-1)" "unprognostic (5.74e-2)" "unprognostic (1.54e-1)" "potential prognostic unfavorable (1.27e-4)" "unprognostic (8.47e-2)" "potential prognostic unfavorable (4.05e-4)" "unprognostic (8.87e-2)" "unprognostic (9.24e-3)" "unprognostic (2.39e-2)" "unprognostic (3.29e-1)" "unprognostic (2.15e-2)" "unprognostic (4.75e-1)" "unprognostic (5.02e-3)" "unprognostic (2.19e-1)" MRTO4 "C1orf33, dJ657E11.4, MRT4" ENSG00000053372 "MRT4 homolog, ribosome maturation factor" Q9UKD2 1 19251805-19260128 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 127.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026446 Approved Approved "Nucleoplasm,Nuclear membrane,Nucleoli" Yes No "Cluster 30: Non-specific - DNA binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 37: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 19 "Nucleoplasm, Nuclear membrane" Nucleoli "HPA026446: " "unprognostic (7.59e-2)" "unprognostic (2.80e-1)" "unprognostic (1.19e-1)" "unprognostic (2.05e-2)" "unprognostic (1.95e-1)" "unprognostic (2.65e-1)" "unprognostic (3.78e-1)" "unprognostic (3.15e-2)" "unprognostic (2.46e-3)" "unprognostic (7.76e-3)" "unprognostic (6.65e-2)" "unprognostic (1.44e-1)" "unprognostic (1.01e-1)" "validated prognostic unfavorable (1.01e-11)" "validated prognostic unfavorable (7.74e-8)" "unprognostic (1.70e-3)" "potential prognostic unfavorable (1.73e-4)" "unprognostic (9.25e-2)" "unprognostic (6.93e-2)" "unprognostic (2.64e-1)" "unprognostic (9.00e-2)" "unprognostic (4.15e-3)" "unprognostic (2.20e-1)" "unprognostic (2.11e-2)" "unprognostic (2.01e-1)" "unprognostic (1.99e-2)" "unprognostic (8.11e-2)" "unprognostic (2.69e-1)" "unprognostic (3.71e-2)" "unprognostic (1.18e-1)" "unprognostic (2.38e-2)" MS4A1 "B1, Bp35, CD20, FMC7" ENSG00000156738 "Membrane spanning 4-domains A1" P11836 11 60455846-60470752 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "B-cell activation" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 631.0" "Cell type enriched" "Detected in some" 52 "B-cells: 884.8" "Cell type enriched" "Detected in single" 99 "leukocyte: 50.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 96 "memory B-cell: 627.9;naive B-cell: 630.0" "Lineage enriched" "Detected in many" 96 "B-cells: 630.0" "Cancer enriched" "Detected in some" 6 "lymphoma: 397.8" "Adrenal gland - T-cells, Lung - B-cells (Lung), Spleen - B-cells (Spleen), Thyroid gland - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000015, HPA014341, HPA014391" Enhanced Supported "Plasma membrane" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 34 "Plasma membrane" "CAB000015: , HPA014341: , HPA014391: " "unprognostic (1.71e-1)" "validated prognostic favorable (3.10e-4)" "validated prognostic favorable (2.75e-5)" "potential prognostic favorable (4.40e-5)" "unprognostic (1.25e-1)" "unprognostic (9.81e-2)" "potential prognostic favorable (9.96e-7)" "unprognostic (6.54e-3)" "unprognostic (9.61e-2)" "unprognostic (1.54e-2)" "potential prognostic favorable (1.29e-4)" "unprognostic (3.75e-2)" "unprognostic (1.21e-1)" "unprognostic (1.31e-1)" "unprognostic (6.53e-2)" "unprognostic (8.62e-2)" "unprognostic (3.32e-1)" "unprognostic (3.46e-2)" "unprognostic (4.36e-2)" "unprognostic (3.36e-3)" "unprognostic (2.04e-1)" "unprognostic (1.93e-1)" "unprognostic (6.81e-2)" "unprognostic (6.82e-2)" MS4A10 "CD20L7, MS4A9" ENSG00000172689 "Membrane spanning 4-domains A10" Q96PG2 11 60785333-60801305 "Predicted membrane proteins, Transporters" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 102 "intestine: 80.7" "Cell type enriched" "Detected in some" 49 "Enterocytes: 340.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA014778 Uncertain NA NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 1: Enterocytes - Absorption and Digestion" 3 "HPA014778: " "unprognostic (1.22e-1)" MS4A12 "FLJ20217, Ms4a10" ENSG00000071203 "Membrane spanning 4-domains A12" Q9NXJ0 11 60492778-60507430 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "intestine: 238.8" "Cell type enriched" "Detected in some" 60 "Colonocytes: 1080.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Colon Adenocarcinoma (TCGA): 11.0;Rectum Adenocarcinoma (TCGA): 15.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enterocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA048616, HPA057657" Enhanced Approved "Nucleoli,Endoplasmic reticulum,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 17: Intestine - Digestion" "Cluster 55: Lymphoma - Immune response" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 5 "Plasma membrane, Cytosol" "Nucleoli, Endoplasmic reticulum, Golgi apparatus" "HPA048616: , HPA057657: " "unprognostic (4.14e-2)" "unprognostic (5.56e-2)" "unprognostic (3.08e-1)" "unprognostic (1.53e-1)" "unprognostic (3.29e-1)" MS4A13 ENSG00000204979 "Membrane spanning 4-domains A13" Q5J8X5 11 60515392-60542721 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 34 "testis: 3.3" "Cell type enhanced" "Detected in some" "Early primary spermatocytes: 10.0;Early spermatids: 22.3;Late primary spermatocytes: 38.9;Late spermatids: 89.3" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045017, HPA063626" Uncertain "Secreted - unknown location" "No annotated function" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 52 "HPA045017: , HPA063626: " MS4A14 "DKFZp434H092, FLJ32856, MS4A16, NYD-SP21" ENSG00000166928 "Membrane spanning 4-domains A14" Q96JA4 11 60378530-60417756 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "testis: 69.3" "Cell type enriched" "Detected in some" 4 "Late spermatids: 1200.0" "Cell type enriched" "Detected in some" 4 "central nervous system macrophage: 26.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 5.5;non-classical monocyte: 8.0" "Lineage enriched" "Detected in many" 5 "monocytes: 8.0" "Cancer enhanced" "Detected in single" "Leukemia: 1.0" "Adipose subcutaneous - Macrophages, Minor Salivary Gland - Macrophages, Skeletal muscle - Macrophages, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA058973 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 47: Testis - Mixed function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 5 Nucleoplasm "Plasma membrane" "HPA058973: " "unprognostic (1.39e-1)" "unprognostic (1.43e-1)" "unprognostic (4.11e-1)" "unprognostic (1.42e-1)" "unprognostic (2.11e-1)" "unprognostic (4.54e-1)" "potential prognostic unfavorable (2.91e-4)" "unprognostic (1.88e-2)" "unprognostic (1.01e-1)" "unprognostic (1.46e-1)" "unprognostic (6.86e-2)" "unprognostic (2.08e-2)" "unprognostic (1.17e-2)" "unprognostic (2.04e-1)" "unprognostic (6.63e-2)" "unprognostic (3.94e-2)" "unprognostic (2.63e-2)" MS4A15 ENSG00000166961 "Membrane spanning 4-domains A15" Q8N5U1 11 60756867-60776733 "Predicted membrane proteins" Receptor "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 12 "lung: 41.0" "Group enriched" "Detected in some" 17 "Alveolar cells type 1: 116.4;Transitional alveolar cells: 100.3" "Cell type enhanced" "Detected in single" "deep-layer corticothalamic and 6b: 2.8" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 22.3" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "T-reg: 3.2" "Lineage enriched" "Detected in single" 12 "T-cells: 3.2" "Cancer enhanced" "Detected in some" "colorectal cancer: 2.1;lung cancer: 2.8;Myeloma: 2.9" "Lung - Alveolar cells type 1" "Region enriched" "Detected in some" 28 "olfactory bulb: 166.8" "Region enriched" "Detected in some" 27 "olfactory bulb: 27.3" HPA054563 Approved "Plasma membrane,Cytosol" NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 13: Lung - Secretion" "Cluster 37: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 81: Alveolar cells - Lung function" "Plasma membrane" Cytosol "HPA054563: " "unprognostic (1.71e-2)" "unprognostic (2.93e-1)" "unprognostic (2.72e-2)" "potential prognostic favorable (3.07e-4)" "unprognostic (2.54e-2)" "unprognostic (8.64e-3)" "unprognostic (2.67e-1)" "unprognostic (1.24e-1)" "unprognostic (3.02e-1)" "unprognostic (1.20e-3)" MS4A18 ENSG00000214782 "Membrane spanning 4-domains A18" Q3C1V0 11 60724720-60745028 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 19 "breast: 5.6;intestine: 17.6" "Cell type enhanced" "Detected in some" "Early spermatids: 7.2;Enterocytes: 7.5;Late primary spermatocytes: 3.0;Late spermatids: 9.2;Parietal cells: 1.8;Prostatic glandular cells: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" HPA045121 Approved NA NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 1: Enterocytes - Absorption and Digestion" "HPA045121: " MS4A2 "APY, FCER1B, IGER" ENSG00000149534 "Membrane spanning 4-domains A2" Q01362 11 60088261-60098467 "FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "IgE-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 11.8" "Cell type enriched" "Detected in some" 129 "Mast cells: 969.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 873 "basophil: 275.8" "Lineage enriched" "Detected in single" 1528 "granulocytes: 275.8" "Cancer enriched" "Detected in single" 14 "Leukemia: 1.9" "Adipose subcutaneous - Mast cells, Colon - Mast cells, Lung - Mast cells, Minor Salivary Gland - Mast cells, Prostate - Fibroblasts, Skin - Mast cells" "Not detected" "Not detected" "Region enhanced" "Detected in all" "spinal cord: 20.9" HPA059967 Enhanced NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 58: Mast cells - Allergic inflammatory responses" 1 "HPA059967: " "unprognostic (5.94e-2)" "unprognostic (1.82e-1)" "unprognostic (7.98e-2)" "validated prognostic favorable (7.36e-4)" "validated prognostic favorable (7.02e-5)" "unprognostic (6.06e-2)" "unprognostic (2.24e-3)" "unprognostic (2.03e-1)" "unprognostic (2.29e-1)" "unprognostic (1.84e-1)" "unprognostic (1.41e-1)" "unprognostic (3.97e-1)" "unprognostic (1.44e-3)" "unprognostic (1.48e-2)" "unprognostic (2.91e-2)" MS4A3 "CD20L, HTM4" ENSG00000149516 "Membrane spanning 4-domains A3" Q96HJ5 11 60056587-60071115 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 96 "bone marrow: 397.1" "Group enriched" "Detected in some" 8 "Monocyte progenitors: 18.9;Neutrophil progenitors: 28.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 1476 "basophil: 2692.2" "Lineage enriched" "Detected in single" 4500 "granulocytes: 2692.2" "Cancer enriched" "Detected in single" 680 "Leukemia: 67.9" "Lung - Neutrophils_1, Spleen - Neutrophils_1" "Not detected" "Not detected" HPA019210 Supported Approved "Golgi apparatus" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 15: Bone marrow - Innate immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 35 "Golgi apparatus" "HPA019210: " MS4A4A "CD20L1, MS4A4, MS4A7" ENSG00000110079 "Membrane spanning 4-domains A4A" Q96JQ5 11 60185657-60318080 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 59.3" "Cell type enhanced" "Detected in many" "cDC: 297.8;Hofbauer cells: 591.2;Kupffer cells: 866.0;Macrophages: 576.1;Mast cells: 163.8;Monocyte progenitors: 163.5;monocytes: 160.0;Neutrophil progenitors: 86.9" "Cell type enriched" "Detected in some" 10 "central nervous system macrophage: 72.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "intermediate monocyte: 61.2;myeloid DC: 27.6;non-classical monocyte: 83.2;plasmacytoid DC: 27.8" "Group enriched" "Detected in many" 30 "dendritic cells: 27.8;monocytes: 83.2" "Cancer enhanced" "Detected in some" "Leukemia: 11.2;Myeloma: 11.2" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Lung - Macrophages, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Spleen - Macrophages, Stomach - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in many" HPA029323 Approved NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 14 "HPA029323: " "unprognostic (2.54e-1)" "unprognostic (7.17e-2)" "unprognostic (3.21e-1)" "potential prognostic favorable (1.80e-4)" "unprognostic (7.74e-2)" "unprognostic (4.53e-2)" "unprognostic (6.64e-3)" "unprognostic (4.98e-2)" "unprognostic (1.29e-1)" "unprognostic (2.22e-1)" "unprognostic (6.39e-2)" "unprognostic (1.98e-1)" "unprognostic (3.37e-2)" "unprognostic (2.96e-2)" "unprognostic (4.37e-2)" "unprognostic (4.81e-2)" "unprognostic (4.95e-2)" "unprognostic (6.81e-2)" "unprognostic (3.67e-1)" "unprognostic (1.47e-2)" "unprognostic (2.49e-1)" "unprognostic (1.55e-1)" "unprognostic (6.20e-2)" "unprognostic (3.65e-1)" "unprognostic (2.96e-2)" "unprognostic (1.81e-2)" "unprognostic (8.16e-2)" "unprognostic (4.66e-3)" "unprognostic (5.63e-2)" "unprognostic (4.90e-2)" "unprognostic (9.82e-2)" MS4A4E ENSG00000214787 "Membrane spanning 4-domains A4E" Q96PG1 11 60200270-60243137 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "cDC: 277.1;Kupffer cells: 248.0;Macrophages: 253.1;Mast cells: 190.7;Monocyte progenitors: 330.0;monocytes: 99.1" "Group enriched" "Detected in some" 7 "central nervous system macrophage: 27.7;leukocyte: 12.8" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 84.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "basophil: 17.9" "Lineage enriched" "Detected in many" 8 "granulocytes: 17.9" "Low cancer specificity" "Detected in all" "Kidney - Macrophages, Pancreas - Macrophages, Skeletal muscle - Macrophages" HPA040075 Uncertain NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" "HPA040075: " "unprognostic (1.79e-1)" "unprognostic (2.68e-1)" "unprognostic (1.24e-1)" "potential prognostic unfavorable (2.03e-5)" "unprognostic (6.86e-2)" "unprognostic (8.84e-3)" "unprognostic (2.47e-2)" "unprognostic (5.08e-2)" "unprognostic (1.62e-2)" "potential prognostic unfavorable (7.63e-9)" "unprognostic (4.17e-2)" "unprognostic (2.00e-1)" "unprognostic (1.28e-1)" "unprognostic (8.60e-3)" "unprognostic (1.32e-1)" "unprognostic (1.67e-3)" "unprognostic (3.53e-2)" "unprognostic (1.55e-1)" "unprognostic (1.41e-1)" "potential prognostic favorable (6.43e-4)" "unprognostic (2.51e-1)" "unprognostic (1.63e-2)" "unprognostic (1.50e-1)" "unprognostic (2.32e-3)" "unprognostic (1.73e-1)" "unprognostic (1.90e-1)" "unprognostic (2.59e-1)" "unprognostic (5.49e-3)" "unprognostic (1.91e-1)" MS4A5 CD20L2 ENSG00000166930 "Membrane spanning 4-domains A5" Q9H3V2 11 60429572-60455214 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 165 "testis: 41.5" "Group enriched" "Detected in some" 251 "Early spermatids: 676.0;Late primary spermatocytes: 379.0;Late spermatids: 1493.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA043732 Uncertain NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" "HPA043732: " MS4A6A "CD20L3, MS4A6" ENSG00000110077 "Membrane spanning 4-domains A6A" Q9H2W1 11 60172015-60184666 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "cDC: 629.4;Hofbauer cells: 465.3;Kupffer cells: 3074.7;Macrophages: 792.1;Monocyte progenitors: 556.2;monocytes: 665.6;Neutrophils: 234.8;pDCs: 416.1" "Cell type enriched" "Detected in some" 5 "central nervous system macrophage: 223.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 8 "basophil: 524.7;classical monocyte: 1399.3;intermediate monocyte: 459.3;myeloid DC: 813.7;plasmacytoid DC: 558.7" "Group enriched" "Detected in all" 70 "dendritic cells: 813.7;granulocytes: 524.7;monocytes: 1399.3" "Cancer enriched" "Detected in some" 8 "Leukemia: 21.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Lung - Macrophages, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Spleen - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid gland - Macrophages" "HPA011391, HPA076623" Approved Approved Vesicles NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 1 Vesicles "HPA011391: , HPA076623: " "unprognostic (8.61e-2)" "unprognostic (2.66e-1)" "unprognostic (2.20e-1)" "unprognostic (1.52e-2)" "unprognostic (5.99e-2)" "unprognostic (2.24e-2)" "unprognostic (6.01e-2)" "unprognostic (1.92e-1)" "unprognostic (6.00e-2)" "unprognostic (1.16e-1)" "unprognostic (3.43e-2)" "unprognostic (3.17e-2)" "unprognostic (5.62e-2)" "unprognostic (2.10e-1)" "unprognostic (5.05e-3)" "unprognostic (9.83e-3)" "unprognostic (9.39e-3)" "unprognostic (8.61e-2)" "unprognostic (4.47e-1)" "unprognostic (6.14e-2)" "unprognostic (2.44e-1)" "unprognostic (2.56e-1)" "unprognostic (2.20e-1)" "unprognostic (2.45e-1)" "unprognostic (5.82e-2)" "unprognostic (1.61e-2)" "unprognostic (3.98e-1)" "unprognostic (8.62e-2)" "unprognostic (1.07e-2)" "unprognostic (9.48e-2)" "unprognostic (3.02e-1)" MS4A6E ENSG00000166926 "Membrane spanning 4-domains A6E" Q96DS6 11 60327255-60396596 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 30 "testis: 19.1" "Group enriched" "Detected in some" 5 "Early spermatids: 1754.0;Late primary spermatocytes: 449.9" "Group enriched" "Detected in some" 13 "central nervous system macrophage: 8.0;lower rhombic lip: 23.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" HPA076623 Approved Vesicles NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 59: Leukemia - T-cell receptor" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 2 Vesicles "HPA076623: " MS4A7 "CD20L4, CFFM4, MS4A8" ENSG00000166927 "Membrane spanning 4-domains A7" Q9GZW8 11 60378485-60395951 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 185.1" "Cell type enriched" "Detected in some" 4 "Kupffer cells: 869.1" "Group enriched" "Detected in some" 10 "central nervous system macrophage: 24.0;leukocyte: 8.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "intermediate monocyte: 749.2;non-classical monocyte: 1495.7" "Lineage enriched" "Detected in many" 12 "monocytes: 1495.7" "Group enriched" "Detected in some" 5 "breast cancer: 2.3;Leukemia: 7.7;lymphoma: 3.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Spleen - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA017418, CAB026387" Approved NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 7 "CAB026387: , HPA017418: " "unprognostic (1.15e-2)" "unprognostic (1.54e-1)" "unprognostic (1.15e-2)" "unprognostic (2.76e-2)" "unprognostic (5.71e-2)" "unprognostic (3.40e-3)" "unprognostic (1.80e-1)" "unprognostic (9.92e-2)" "unprognostic (3.91e-1)" "unprognostic (4.90e-2)" "unprognostic (4.77e-2)" "unprognostic (1.27e-1)" "unprognostic (7.37e-2)" "unprognostic (2.01e-1)" "unprognostic (7.13e-3)" "unprognostic (3.60e-3)" "unprognostic (4.83e-2)" "unprognostic (6.64e-2)" "unprognostic (1.18e-1)" "unprognostic (1.23e-3)" "unprognostic (1.12e-2)" "unprognostic (1.99e-1)" "unprognostic (2.90e-1)" "unprognostic (1.64e-1)" "unprognostic (8.05e-2)" "unprognostic (1.39e-1)" "unprognostic (1.68e-2)" "unprognostic (5.01e-3)" "unprognostic (8.85e-3)" "unprognostic (2.69e-1)" "unprognostic (3.32e-1)" MS4A8 "CD20L5, MS4A4, MS4A8B" ENSG00000166959 "Membrane spanning 4-domains A8" Q9BY19 11 60699585-60715807 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 122.0;intestine: 186.2" "Group enriched" "Detected in many" 4 "Endometrial ciliated cells: 1182.7;Enterocytes: 767.9;Epididymal efferent duct ciliated cells: 452.0;Fallopian tube ciliated cells: 376.6;Neuroendocrine cells: 670.9;Respiratory ciliated cells: 872.4" "Cell type enhanced" "Detected in some" "amygdala excitatory: 8.1;choroid plexus epithelial cell: 9.8;upper-layer intratelencephalic: 9.3" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 28.7;Uterine Corpus Endometrial Carcinoma (TCGA): 30.0" "Region enhanced" "Detected in many" "choroid plexus: 11.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 8 "lung cancer: 11.2" "Adrenal gland - Adrenal medulla cells, Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Stomach - Gastric enteroendocrine cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA007319 Enhanced NA NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" "HPA007319: " "unprognostic (5.34e-1)" "unprognostic (3.08e-3)" "unprognostic (2.94e-1)" "unprognostic (1.38e-1)" "unprognostic (5.58e-2)" "unprognostic (1.79e-2)" "unprognostic (2.28e-1)" "unprognostic (2.25e-2)" "unprognostic (3.51e-1)" "unprognostic (6.63e-2)" "unprognostic (2.05e-1)" "unprognostic (7.25e-3)" "unprognostic (1.11e-2)" "unprognostic (1.11e-1)" "unprognostic (6.29e-2)" "unprognostic (1.89e-3)" "unprognostic (1.94e-1)" "unprognostic (3.61e-1)" MSANTD1 "C4orf44, LOC345222" ENSG00000188981 "Myb/SANT DNA binding domain containing 1" Q6ZTZ1 4 3244369-3271738 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 5.7;testis: 3.9" "Cell type enhanced" "Detected in many" "Early spermatids: 47.2;Late primary spermatocytes: 13.5;Late spermatids: 46.2;Myonuclei: 13.3;Pancreatic islet cells: 13.4" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA047003 Approved Nucleoplasm,Cytosol NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" Nucleoplasm Cytosol "HPA047003: " "unprognostic (1.14e-3)" MSANTD2 "C11orf61, FLJ23342" ENSG00000120458 "Myb/SANT DNA binding domain containing 2" Q6P1R3 11 124766498-124800706 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038694, HPA038695" Approved Approved Mitochondria NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 56: Non-specific - Sensory perception" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" Mitochondria "HPA038694: , HPA038695: " "unprognostic (1.71e-1)" "unprognostic (1.18e-1)" "unprognostic (1.16e-1)" "unprognostic (3.23e-3)" "unprognostic (4.36e-1)" "unprognostic (2.55e-1)" "unprognostic (2.23e-3)" "unprognostic (5.85e-2)" "unprognostic (1.72e-1)" "unprognostic (7.37e-2)" "unprognostic (1.11e-3)" "unprognostic (2.05e-1)" "unprognostic (2.37e-3)" "unprognostic (1.58e-1)" "unprognostic (5.99e-2)" "unprognostic (2.04e-1)" "unprognostic (1.84e-2)" "unprognostic (2.60e-1)" "unprognostic (1.89e-2)" "unprognostic (5.91e-2)" "unprognostic (1.29e-2)" "unprognostic (1.75e-2)" "unprognostic (5.59e-2)" "unprognostic (1.76e-1)" "potential prognostic unfavorable (3.52e-4)" "unprognostic (7.42e-2)" "unprognostic (1.48e-1)" "unprognostic (2.40e-2)" "unprognostic (1.53e-1)" MSANTD3 "C9orf30, MGC17337" ENSG00000066697 "Myb/SANT DNA binding domain containing 3" Q96H12 9 100427143-100451734 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 36.9;Brain inhibitory neurons: 31.5;Oligodendrocyte progenitor cells: 31.8;Oligodendrocytes: 31.5;Other brain neurons: 35.4;Platelets: 35.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062662, HPA076132" Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 37: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 98: Neurons - Neurotransmission & signaling" 3 Nucleoplasm "Nuclear bodies, Cytosol" "HPA062662: , HPA076132: " "unprognostic (1.09e-1)" "unprognostic (9.25e-2)" "unprognostic (1.74e-3)" "unprognostic (1.25e-1)" "unprognostic (1.25e-2)" "unprognostic (4.00e-2)" "unprognostic (4.70e-2)" "potential prognostic unfavorable (4.62e-4)" "unprognostic (1.15e-1)" "unprognostic (2.72e-3)" "unprognostic (5.93e-2)" "unprognostic (6.48e-3)" "potential prognostic unfavorable (1.49e-5)" "potential prognostic unfavorable (1.68e-4)" "unprognostic (5.66e-3)" "unprognostic (7.90e-3)" "unprognostic (6.36e-2)" "unprognostic (4.86e-2)" "unprognostic (1.73e-1)" "unprognostic (4.08e-2)" "unprognostic (2.89e-2)" "unprognostic (1.61e-1)" "unprognostic (3.26e-2)" "unprognostic (1.26e-1)" "unprognostic (4.51e-1)" "unprognostic (1.56e-1)" "unprognostic (2.85e-1)" "unprognostic (6.81e-2)" "unprognostic (4.80e-3)" MSANTD3-TMEFF1 C9orf30-TMEFF1 ENSG00000251349 "MSANTD3-TMEFF1 readthrough" 9 100442271-100577636 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 6 "brain: 31.6" "Cell type enhanced" "Detected in many" "Melanocytes: 8.0;Platelets: 8.5;Retinal horizontal cells: 8.0;Schwann cells: 7.2;Smooth muscle cells: 7.2;Tuft cells: 11.5" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 15.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in all" 4 "Neuroblastoma: 35.8;testis cancer: 64.8" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 34: Non-specific - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 17: Non-specific - RNA processing" "unprognostic (1.29e-2)" "unprognostic (8.61e-2)" "unprognostic (5.53e-2)" "unprognostic (9.25e-2)" "unprognostic (1.42e-1)" "unprognostic (3.08e-1)" "unprognostic (3.13e-3)" "unprognostic (1.31e-2)" "unprognostic (6.30e-2)" "unprognostic (4.52e-2)" "unprognostic (4.02e-3)" "unprognostic (6.21e-3)" "unprognostic (2.19e-2)" "unprognostic (1.88e-1)" "unprognostic (1.77e-1)" "unprognostic (3.72e-1)" "unprognostic (1.40e-2)" "unprognostic (6.19e-2)" "unprognostic (2.73e-1)" "unprognostic (1.83e-1)" "unprognostic (1.03e-1)" "unprognostic (1.28e-2)" "unprognostic (2.69e-1)" "unprognostic (1.57e-1)" "unprognostic (3.47e-1)" MSANTD4 KIAA1826 ENSG00000170903 "Myb/SANT DNA binding domain containing 4 with coiled-coils" Q8NCY6 11 105995623-106022403 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bergmann glia: 71.2;Müller glia: 150.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014411 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 34: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 11: Muller glia cells - Retinal homeostasis" 10 Nucleoplasm Cytosol "HPA014411: " "unprognostic (3.97e-2)" "unprognostic (2.33e-3)" "unprognostic (2.21e-2)" "unprognostic (3.34e-2)" "unprognostic (1.59e-1)" "unprognostic (3.37e-2)" "unprognostic (1.44e-1)" "unprognostic (6.97e-2)" "unprognostic (5.51e-2)" "potential prognostic favorable (9.30e-6)" "unprognostic (1.62e-2)" "unprognostic (2.24e-3)" "unprognostic (1.40e-2)" "unprognostic (1.75e-1)" "unprognostic (2.15e-1)" "unprognostic (1.60e-1)" "unprognostic (2.08e-3)" "unprognostic (5.14e-2)" "unprognostic (1.46e-2)" "unprognostic (4.06e-2)" "unprognostic (6.19e-1)" "unprognostic (1.60e-1)" "unprognostic (1.36e-2)" "unprognostic (2.38e-2)" "unprognostic (5.90e-2)" "unprognostic (2.64e-1)" "unprognostic (2.39e-1)" "unprognostic (1.68e-2)" "unprognostic (1.29e-1)" MSANTD5 ENSG00000285891 "Myb/SANT DNA binding domain containing 5" A0A3B3IT52 5 178694572-178697761 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 18 "testis: 2.4" "Cell type enriched" "Detected in single" 4 "Late spermatids: 2.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" MSANTD7 ENSG00000284024 "Myb/SANT DNA binding domain containing 7" 10 14838302-14846999 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Megakaryocytes: 6.2;Melanocytes: 2.3" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Inner root sheath cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 35: Non-specific - DNA binding" "Cluster 52: Non-specific - Mitochondria" "Cluster 47: Platelets - Hemostasis" "unprognostic (1.26e-1)" "unprognostic (6.27e-2)" "unprognostic (2.50e-1)" "unprognostic (1.49e-1)" "unprognostic (3.65e-1)" "unprognostic (1.27e-2)" "unprognostic (5.17e-2)" "unprognostic (5.65e-3)" "unprognostic (4.30e-3)" "unprognostic (2.71e-1)" "unprognostic (1.28e-2)" "potential prognostic unfavorable (2.31e-6)" "unprognostic (5.85e-2)" "unprognostic (1.82e-2)" "unprognostic (5.10e-3)" "unprognostic (1.13e-1)" "unprognostic (1.77e-1)" "unprognostic (3.72e-2)" "unprognostic (4.42e-2)" "unprognostic (2.38e-2)" "unprognostic (1.43e-1)" "unprognostic (2.58e-1)" "unprognostic (6.55e-2)" "unprognostic (1.83e-1)" "unprognostic (4.31e-2)" "unprognostic (1.50e-1)" MSC "ABF-1, bHLHa22" ENSG00000178860 Musculin O60682 8 71841560-71844412 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 54.6" "Cell type enhanced" "Detected in some" "Adipocytes: 9.6;Fibroblasts: 25.5;Hepatic stellate cells: 32.3;Leydig cells: 28.0;Melanocytes: 50.7;Myosatellite cells: 35.6;Pericytes: 27.3;Peritubular myoid cells: 35.9;Vascular smooth muscle cells: 13.1" "Cell type enhanced" "Detected in some" "hippocampal CA4: 7.0;pericyte: 15.5;vascular associated smooth muscle cell: 12.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "memory CD8 T-cell: 25.8" "Group enriched" "Detected in many" 37 "B-cells: 6.9;dendritic cells: 6.4;T-cells: 25.8" "Low cancer specificity" "Detected in many" "Prostate - Fibroblasts" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 8 "cerebral cortex: 21.5;hippocampal formation: 17.4" HPA062878 Supported Nucleoplasm NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 51: Neurons - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 7 Nucleoplasm "HPA062878: " "unprognostic (1.08e-1)" "unprognostic (1.21e-1)" "unprognostic (9.03e-2)" "unprognostic (5.34e-2)" "unprognostic (5.30e-2)" "unprognostic (1.70e-1)" "unprognostic (1.48e-2)" "unprognostic (1.18e-1)" "unprognostic (1.76e-2)" "unprognostic (9.91e-3)" "potential prognostic unfavorable (2.61e-6)" "unprognostic (2.79e-3)" "unprognostic (2.98e-3)" "potential prognostic unfavorable (7.72e-5)" "unprognostic (8.21e-2)" "unprognostic (1.02e-1)" "unprognostic (1.53e-2)" "unprognostic (4.70e-2)" "unprognostic (5.56e-2)" "unprognostic (3.45e-2)" "unprognostic (2.57e-2)" "unprognostic (2.46e-1)" "unprognostic (7.75e-2)" "unprognostic (3.67e-1)" "unprognostic (7.10e-3)" "unprognostic (4.52e-2)" "unprognostic (6.22e-2)" "unprognostic (5.31e-3)" "unprognostic (2.16e-1)" "unprognostic (7.96e-2)" "unprognostic (3.23e-2)" MSGN1 pMesogenin1 ENSG00000151379 "Mesogenin 1" A6NI15 2 17816460-17817798 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 5 "choroid plexus: 1.1" "Cell type enhanced" "Detected in single" "Sertoli cells: 1.1" "Cell type enhanced" "Detected in single" "choroid plexus epithelial cell: 1.1" "Not detected" "Not detected" "Region enhanced" "Detected in single" "choroid plexus: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA067516 Approved "Acrosome,Equatorial segment,Mid piece" NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 24 "Acrosome, Equatorial segment, Mid piece" "HPA067516: " MSH2 "COCA1, HNPCC, HNPCC1, MSH-2" ENSG00000095002 "MutS homolog 2" P43246 2 47403067-47663146 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" DNA-binding "Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 294.0;Erythrocyte progenitors: 145.5;Rod photoreceptor cells: 158.9" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 90.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009572, HPA066845, CAB070867, CAB080131" Supported Supported Nucleoplasm NA Yes 18000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 31: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 79: Photoreceptor cells - Phototransduction" 79 Nucleoplasm "CAB009572: , CAB070867: , CAB080131: , HPA066845: " "unprognostic (1.50e-1)" "unprognostic (3.35e-1)" "unprognostic (1.19e-1)" "unprognostic (2.42e-1)" "unprognostic (3.56e-2)" "unprognostic (2.54e-1)" "unprognostic (3.41e-1)" "unprognostic (3.90e-3)" "unprognostic (9.82e-2)" "potential prognostic unfavorable (4.89e-4)" "potential prognostic favorable (1.29e-4)" "unprognostic (1.38e-1)" "unprognostic (2.10e-2)" "validated prognostic unfavorable (2.60e-7)" "validated prognostic unfavorable (3.63e-5)" "unprognostic (1.73e-2)" "unprognostic (1.64e-2)" "potential prognostic favorable (1.22e-4)" "unprognostic (3.47e-2)" "unprognostic (3.37e-1)" "unprognostic (1.66e-1)" "unprognostic (3.51e-3)" "unprognostic (1.13e-3)" "unprognostic (5.04e-2)" "unprognostic (5.02e-3)" "unprognostic (1.20e-1)" "unprognostic (1.03e-2)" "unprognostic (8.53e-3)" "unprognostic (1.83e-1)" "unprognostic (2.86e-1)" "unprognostic (4.95e-2)" MSH3 "DUP, MRP1" ENSG00000113318 "MutS homolog 3" P20585 5 80654652-80876815 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin), Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036081 Approved "Nuclear bodies" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 7: Non-specific - Ribosome" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 23 "Nuclear bodies" "HPA036081: " "unprognostic (6.43e-3)" "unprognostic (2.74e-1)" "unprognostic (4.01e-1)" "unprognostic (4.56e-2)" "unprognostic (4.98e-3)" "unprognostic (6.85e-2)" "unprognostic (1.49e-1)" "unprognostic (7.09e-2)" "unprognostic (8.67e-2)" "potential prognostic unfavorable (5.21e-5)" "potential prognostic favorable (2.69e-10)" "unprognostic (8.56e-3)" "unprognostic (5.10e-2)" "unprognostic (2.66e-1)" "unprognostic (2.09e-1)" "unprognostic (2.28e-2)" "unprognostic (1.56e-1)" "unprognostic (3.18e-1)" "unprognostic (3.88e-1)" "unprognostic (4.98e-2)" "potential prognostic unfavorable (4.37e-4)" "unprognostic (2.05e-2)" "unprognostic (1.73e-2)" "unprognostic (1.59e-1)" "unprognostic (2.82e-2)" "unprognostic (9.93e-2)" "unprognostic (3.49e-1)" "unprognostic (3.26e-3)" "unprognostic (1.94e-1)" "unprognostic (4.31e-3)" "unprognostic (1.72e-1)" MSH4 ENSG00000057468 "MutS homolog 4" O15457 1 75796882-75913242 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Meiosis DNA-binding "Disease variant, Premature ovarian failure" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 1.7;testis: 4.0" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 23.7;Brain inhibitory neurons: 23.1;Early primary spermatocytes: 81.5;Late primary spermatocytes: 20.0;Myonuclei: 85.5;Papillary tip epithelial cells: 19.9;Retinal ganglion cells: 23.2;Retinal horizontal cells: 48.1" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA028117 Approved "Nucleoplasm,Equatorial segment,Flagellar centriole,Mid piece" NA NA "Cluster 67: Testis - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 12 Nucleoplasm "Equatorial segment, Flagellar centriole, Mid piece" "HPA028117: " "unprognostic (4.88e-2)" MSH5 G7 ENSG00000204410 "MutS homolog 5" O43196 6 31739677-31762676 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Meiosis" DNA-binding "Disease variant, Premature ovarian failure" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 11.3" "Cell type enhanced" "Detected in some" "Astrocytes: 14.0;Bergmann glia: 10.3;Brain inhibitory neurons: 4.7;Choroid plexus epithelial cells: 21.2;Early primary spermatocytes: 3.6;Ependymal cells: 27.4;Microglia: 16.3;Oligodendrocyte progenitor cells: 5.1;Oligodendrocytes: 5.0;Other brain neurons: 6.2" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "basophil: 2.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA078319 Approved "Nucleoli fibrillar center" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 67: Testis - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 22: Non-specific - Basic cellular functions" 7 "Nucleoli fibrillar center" "HPA078319: " "unprognostic (1.07e-1)" "unprognostic (1.50e-1)" "unprognostic (8.01e-3)" "unprognostic (1.80e-2)" "unprognostic (2.27e-2)" MSH6 "GTBP, MSH-6" ENSG00000116062 "MutS homolog 6" P52701 2 47695530-47810063 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction" DNA-binding "Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epicardial cells: 261.5" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 117.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009091, HPA028376, HPA028446, CAB070870" Enhanced Approved "Nucleoplasm,Golgi apparatus,Vesicles,Cytosol" NA Yes 9400 "Cluster 33: Non-specific - ATP binding" "Cluster 75: Ovary - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 70 "Nucleoplasm, Golgi apparatus, Vesicles" Cytosol "CAB009091: , CAB070870: , HPA028376: , HPA028446: " "unprognostic (4.23e-1)" "unprognostic (8.73e-2)" "unprognostic (1.82e-2)" "unprognostic (3.18e-1)" "unprognostic (2.27e-1)" "unprognostic (1.71e-1)" "unprognostic (3.04e-1)" "unprognostic (2.19e-2)" "unprognostic (2.80e-1)" "potential prognostic unfavorable (5.35e-4)" "unprognostic (7.60e-3)" "unprognostic (1.20e-1)" "potential prognostic unfavorable (2.54e-4)" "unprognostic (1.73e-3)" "potential prognostic unfavorable (2.16e-4)" "unprognostic (3.64e-2)" "unprognostic (1.55e-3)" "unprognostic (1.53e-2)" "unprognostic (8.87e-2)" "unprognostic (2.21e-1)" "unprognostic (9.64e-2)" "unprognostic (8.75e-3)" "potential prognostic unfavorable (2.16e-4)" "unprognostic (2.24e-2)" "unprognostic (5.55e-2)" "unprognostic (1.94e-1)" "unprognostic (7.87e-2)" "unprognostic (3.33e-1)" "unprognostic (1.96e-1)" "unprognostic (1.82e-1)" "unprognostic (3.83e-1)" MSI1 ENSG00000135097 "Musashi RNA binding protein 1" O43347 12 120341330-120369164 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "retina: 96.8" "Cell type enhanced" "Detected in many" "Bergmann glia: 45.0;Choroid plexus epithelial cells: 59.0;Cone photoreceptor cells: 99.4;Early spermatids: 73.4;Ependymal cells: 57.2;Late spermatids: 91.6;Müller glia: 135.4;Paneth cells: 46.4;Retinal pigment epithelial cells: 63.9;Rod photoreceptor cells: 186.1" "Cell type enhanced" "Detected in many" "Bergmann glia: 53.9;choroid plexus epithelial cell: 62.3;ependymal cell: 64.3" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 29.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 22.0" "Adipose visceral - Mesothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA074923, HPA075573" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 39: Astrocytes - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 79: Photoreceptor cells - Phototransduction" 13 "Nucleoplasm, Cytosol" "HPA074923: , HPA075573: " "unprognostic (3.15e-2)" "unprognostic (2.12e-1)" "unprognostic (2.71e-1)" "unprognostic (2.72e-3)" "unprognostic (2.29e-1)" "unprognostic (1.08e-1)" "unprognostic (4.28e-1)" "unprognostic (2.81e-1)" "unprognostic (4.54e-2)" "unprognostic (4.86e-3)" "unprognostic (3.42e-2)" "unprognostic (1.04e-2)" "unprognostic (5.80e-2)" "unprognostic (6.58e-2)" "unprognostic (1.31e-3)" "unprognostic (8.89e-2)" "unprognostic (1.19e-1)" "potential prognostic favorable (3.20e-4)" "unprognostic (5.01e-2)" "unprognostic (6.24e-2)" "unprognostic (2.19e-2)" "unprognostic (1.77e-2)" "unprognostic (5.32e-2)" "unprognostic (8.45e-2)" "unprognostic (1.40e-2)" "unprognostic (1.22e-2)" MSI2 ENSG00000153944 "Musashi RNA binding protein 2" Q96DH6 17 57255851-57684689 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 116.8" "Cell type enhanced" "Detected in all" "Choroid plexus epithelial cells: 2522.2;Hematopoietic stem cells: 2363.0;Pituicytes/FSCs: 2836.6;Rod photoreceptor cells: 1742.4" "Cell type enhanced" "Detected in all" "astrocyte: 1911.3;choroid plexus epithelial cell: 2100.8;ependymal cell: 1777.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022300, HPA068990" Approved Supported Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 6: Leukemia - Signal transduction" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 14 Cytosol "CAB022300: , HPA068990: " "potential prognostic favorable (1.12e-4)" "unprognostic (1.63e-2)" "unprognostic (2.96e-1)" "unprognostic (7.24e-2)" "unprognostic (3.04e-2)" "unprognostic (1.07e-1)" "unprognostic (3.12e-1)" "unprognostic (4.47e-1)" "unprognostic (3.32e-1)" "unprognostic (2.29e-2)" "potential prognostic favorable (2.11e-4)" "unprognostic (7.37e-2)" "unprognostic (3.17e-2)" "unprognostic (3.22e-2)" "unprognostic (1.67e-3)" "unprognostic (1.23e-1)" "unprognostic (3.29e-2)" "unprognostic (1.62e-1)" "potential prognostic favorable (3.20e-4)" "unprognostic (1.60e-1)" "unprognostic (2.92e-1)" "unprognostic (1.38e-1)" "unprognostic (2.16e-1)" "unprognostic (1.22e-1)" "unprognostic (1.35e-1)" "unprognostic (2.74e-2)" "unprognostic (1.08e-1)" "unprognostic (1.54e-3)" "unprognostic (3.76e-2)" "unprognostic (1.62e-1)" "unprognostic (4.28e-1)" MSL1 "DKFZp686P24239, hMSL1, MSL-1" ENSG00000188895 "MSL complex subunit 1" Q68DK7 17 40121971-40136917 "Predicted intracellular proteins" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Neutrophils: 604.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "neutrophil: 8.7" "Lineage enriched" "Detected in many" 5 "granulocytes: 8.7" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022800, HPA023567" Uncertain Enhanced "Nucleoplasm,Nuclear speckles,Vesicles" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 24: Non-specific - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" 20 Nucleoplasm "Nuclear speckles, Vesicles" "HPA022800: , HPA023567: " "unprognostic (9.70e-2)" "unprognostic (1.00e-1)" "unprognostic (3.44e-2)" "unprognostic (5.95e-2)" "unprognostic (1.44e-1)" "unprognostic (1.23e-2)" "unprognostic (1.80e-1)" "potential prognostic favorable (7.31e-4)" "unprognostic (1.11e-1)" "unprognostic (3.30e-2)" "unprognostic (2.05e-1)" "unprognostic (2.25e-1)" "unprognostic (2.88e-1)" "unprognostic (3.12e-2)" "unprognostic (1.52e-2)" "unprognostic (1.24e-1)" "unprognostic (2.96e-1)" "unprognostic (2.63e-1)" "unprognostic (1.32e-1)" "unprognostic (7.29e-2)" "unprognostic (1.08e-1)" "unprognostic (1.17e-1)" "unprognostic (1.48e-2)" "unprognostic (3.75e-1)" "potential prognostic favorable (2.25e-4)" "unprognostic (2.43e-2)" "unprognostic (6.20e-2)" "unprognostic (9.11e-3)" "unprognostic (2.41e-1)" "unprognostic (9.15e-2)" "unprognostic (3.10e-1)" MSL2 "FLJ10546, KIAA1585, msl-2, MSL2L1, RNF184" ENSG00000174579 "MSL complex subunit 2" Q9HCI7 3 136148917-136197241 "Predicted intracellular proteins" "DNA damage, Ubl conjugation pathway" "Chromatin regulator, Transferase" "Autism spectrum disorder, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 58.7" "Cell type enhanced" "Detected in all" "Neutrophils: 227.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003413 Uncertain Approved Nucleoplasm,Cytosol NA No "Cluster 21: Neutrophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 16: Non-specific - Transcription" "Cluster 59: Leukemia - T-cell receptor" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 13 "Nucleoplasm, Cytosol" "HPA003413: " "unprognostic (2.11e-2)" "unprognostic (9.75e-2)" "unprognostic (6.97e-3)" "unprognostic (4.99e-1)" "unprognostic (1.18e-1)" "unprognostic (1.22e-1)" "unprognostic (1.39e-1)" "unprognostic (8.37e-3)" "unprognostic (1.58e-2)" "unprognostic (5.02e-2)" "potential prognostic favorable (4.30e-5)" "unprognostic (2.65e-3)" "unprognostic (1.21e-1)" "unprognostic (4.10e-2)" "unprognostic (9.76e-2)" "unprognostic (5.71e-2)" "unprognostic (7.33e-2)" "unprognostic (3.43e-1)" "unprognostic (7.33e-2)" "unprognostic (3.39e-2)" "unprognostic (1.70e-1)" "unprognostic (1.23e-1)" "unprognostic (1.63e-2)" "unprognostic (5.15e-2)" "unprognostic (4.88e-2)" "unprognostic (2.36e-1)" "unprognostic (7.39e-2)" "unprognostic (2.17e-1)" "unprognostic (1.89e-1)" "unprognostic (2.84e-2)" "unprognostic (2.16e-1)" MSL3 MSL3L1 ENSG00000005302 "MSL complex subunit 3" Q8N5Y2 X 11758159-11775772 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophil progenitors: 100.3;Neutrophils: 359.3;Oocytes: 193.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034535, HPA034536" Uncertain Approved Nucleoplasm NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 55: Lymphoma - Immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 7 Nucleoplasm "HPA034535: , HPA034536: " "unprognostic (9.98e-2)" "unprognostic (2.59e-2)" "unprognostic (5.81e-2)" "potential prognostic unfavorable (1.22e-4)" "unprognostic (5.95e-2)" "unprognostic (2.42e-1)" "unprognostic (2.55e-1)" "unprognostic (5.42e-2)" "unprognostic (1.13e-2)" "unprognostic (1.40e-2)" "unprognostic (1.92e-3)" "unprognostic (1.75e-1)" "unprognostic (1.66e-1)" "potential prognostic unfavorable (1.42e-4)" "unprognostic (2.50e-1)" "unprognostic (4.74e-2)" "unprognostic (5.94e-3)" "unprognostic (3.00e-1)" "unprognostic (8.83e-2)" "unprognostic (6.70e-2)" "unprognostic (1.57e-1)" "unprognostic (9.27e-2)" "potential prognostic unfavorable (9.55e-4)" "unprognostic (2.73e-1)" "unprognostic (6.07e-2)" "unprognostic (6.00e-2)" "unprognostic (2.26e-1)" "unprognostic (9.16e-2)" "unprognostic (9.52e-2)" "unprognostic (5.16e-2)" "unprognostic (1.87e-1)" MSLN "CAK1, MPF" ENSG00000102854 Mesothelin Q13421 16 760734-768865 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 89.2;fallopian tube: 261.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 375.8;Conjunctival goblet cells: 998.0;Endometrial luminal cells: 129.4;Endometrial secretory cells: 125.4;Fallopian secretory cells: 685.4;Mesothelial cells: 266.2;Respiratory deuterosomal cells: 215.6;Respiratory secretory cells: 215.0;Salivary duct cells: 115.0;Transitional alveolar cells: 127.0" "Cell type enriched" "Detected in single" 16 "central nervous system macrophage: 6.8" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 473.2;Ovary Serous Cystadenocarcinoma (TCGA): 670.7" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "myeloid DC: 5.9" "Group enriched" "Detected in many" 39 "dendritic cells: 5.9;monocytes: 1.8" "Cancer enhanced" "Detected in many" "ovarian cancer: 100.1;pancreatic cancer: 97.1" "Adipose visceral - Mesothelial cells, Pancreas - Ductal cells, Prostate - Urothelial cells, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in many" "Region enriched" "Detected in single" 9 "spinal cord: 3.8" "CAB002216, HPA017172, CAB080356, CAB080357" Enhanced Supported "Vesicles,Plasma membrane" "Intracellular and membrane" "Cell adhesion" NA NA 9400000 "Cluster 40: Monocytes - Innate immune response" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 18: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 38: Secretory epithelial cells - Exocrine secretion" "Vesicles, Plasma membrane" "CAB002216: , CAB080356: , CAB080357: , HPA017172: " "unprognostic (5.68e-3)" "unprognostic (1.17e-1)" "unprognostic (2.01e-1)" "unprognostic (2.65e-1)" "unprognostic (9.28e-2)" "unprognostic (1.09e-1)" "unprognostic (4.96e-2)" "unprognostic (4.27e-2)" "unprognostic (1.84e-1)" "unprognostic (1.45e-2)" "unprognostic (1.86e-1)" "potential prognostic favorable (6.79e-4)" "unprognostic (8.03e-2)" "unprognostic (1.33e-1)" "unprognostic (3.22e-2)" "unprognostic (2.51e-2)" "unprognostic (4.61e-2)" "unprognostic (2.41e-1)" "unprognostic (1.59e-2)" "unprognostic (2.73e-2)" "unprognostic (1.24e-3)" "unprognostic (7.87e-3)" "unprognostic (1.18e-1)" "unprognostic (9.57e-3)" "unprognostic (3.20e-1)" "unprognostic (5.29e-3)" "unprognostic (1.27e-1)" "unprognostic (1.10e-2)" "unprognostic (7.09e-2)" MSLNL "C16orf37, MPFL" ENSG00000162006 "Mesothelin like" Q96KJ4 16 769428-783370 "Predicted membrane proteins" "Cell adhesion" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 9 "Epicardial cells: 79.6" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Lung Adenocarcinoma (TCGA): 1.5;Ovary Serous Cystadenocarcinoma (TCGA): 2.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 2.6;ovarian cancer: 3.3" "Adipose visceral - Mesothelial cells, Prostate - Urothelial cells, Skin - Outer root sheath cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 15: Kidney cancer - Membrane components" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" "unprognostic (1.64e-2)" "unprognostic (4.11e-2)" "unprognostic (2.50e-1)" MSMB "IGBF, MSP, MSPB, PN44, PRPS, PSP, PSP-94, PSP57, PSP94" ENSG00000263639 "Microseminoprotein beta" P08118 10 46033307-46048180 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 17 "prostate: 8771.6" "Cell type enriched" "Detected in many" 4 "Prostatic glandular cells: 24515.5" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 26 "Prostate Adenocarcinoma (TCGA): 7341.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 18 "prostate cancer: 295.9" "Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB026357, HPA051257" Enhanced "Secreted in male reproductive system" "No annotated function" NA NA 3100000 "Cluster 38: Non-specific - Basic cellular processes" "Cluster 60: Prostate cancer - Unknown function" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 2 "CAB026357: , HPA051257: " "unprognostic (1.07e-1)" "unprognostic (3.19e-2)" "unprognostic (1.40e-1)" "unprognostic (5.36e-3)" "unprognostic (2.38e-1)" "unprognostic (1.50e-3)" "unprognostic (2.49e-2)" "unprognostic (1.65e-1)" "unprognostic (3.43e-3)" "unprognostic (1.50e-2)" "unprognostic (7.03e-2)" "unprognostic (2.63e-2)" "unprognostic (3.07e-2)" "unprognostic (1.65e-1)" "unprognostic (3.24e-1)" "unprognostic (1.23e-1)" "unprognostic (8.74e-2)" "unprognostic (1.80e-1)" "unprognostic (2.22e-1)" "unprognostic (2.14e-1)" "unprognostic (4.04e-1)" MSMO1 "DESP4, ERG25, SC4MOL" ENSG00000052802 "Methylsterol monooxygenase 1" Q15800 4 165327667-165343164 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 537.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 526.4;Breast lactating cells: 817.4;Epididymal principal cells: 1438.3;Esophageal apical cells: 981.0;Esophageal suprabasal cells: 427.7;Hepatocytes: 346.5;Urothelial cells: 413.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055073, HPA056127" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 48 "Endoplasmic reticulum" "HPA055073: , HPA056127: " "unprognostic (1.02e-1)" "unprognostic (4.25e-3)" "potential prognostic unfavorable (9.73e-4)" "unprognostic (1.73e-1)" "unprognostic (2.57e-2)" "unprognostic (3.58e-1)" "unprognostic (5.01e-3)" "unprognostic (1.78e-3)" "unprognostic (2.39e-2)" "potential prognostic favorable (1.59e-4)" "unprognostic (1.04e-1)" "unprognostic (1.66e-1)" "unprognostic (1.11e-1)" "unprognostic (6.61e-3)" "unprognostic (5.82e-2)" "unprognostic (1.50e-1)" "unprognostic (4.98e-2)" "unprognostic (3.64e-1)" "unprognostic (1.93e-2)" "potential prognostic unfavorable (4.88e-4)" "unprognostic (1.00e-1)" "unprognostic (6.69e-2)" "unprognostic (8.50e-2)" "unprognostic (2.98e-1)" "unprognostic (1.84e-3)" "unprognostic (2.72e-1)" "unprognostic (2.35e-1)" "unprognostic (9.87e-2)" "unprognostic (4.34e-2)" MSMP "PC-3, PSMP" ENSG00000215183 "Microseminoprotein, prostate associated" Q1L6U9 9 35752990-35756613 "Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 3.1;pituitary gland: 1.3;placenta: 1.1" "Group enriched" "Detected in some" 7 "Early spermatids: 123.6;Late spermatids: 326.4" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 61.7;Thyroid Carcinoma (TCGA): 34.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 13 "prostate cancer: 70.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA055174 Uncertain Supported Vesicles,Cytosol "Secreted in other tissues" Cytokine No No 14000 "Cluster 41: Basophils - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" Vesicles Cytosol "HPA055174: " "unprognostic (6.84e-2)" "unprognostic (4.28e-2)" "unprognostic (3.84e-1)" "unprognostic (1.37e-1)" "unprognostic (3.17e-1)" "unprognostic (3.13e-2)" "unprognostic (9.34e-2)" "unprognostic (4.73e-2)" "unprognostic (2.66e-1)" "unprognostic (2.41e-2)" "unprognostic (1.95e-1)" "unprognostic (4.36e-1)" "unprognostic (5.59e-2)" "unprognostic (4.75e-2)" MSN ENSG00000147065 Moesin P26038 X 65588377-65741931 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 480.3;Megakaryocytes: 544.0;Monocyte progenitors: 438.5;monocytes: 512.9;Neutrophil progenitors: 510.8;Neutrophils: 900.6;Platelets: 881.1;Vascular endothelial cells: 465.1" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 212.6;endothelial cell: 342.0;leukocyte: 365.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Pituitary gland - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000263, CAB010898, HPA011135, HPA011227, CAB047336, CAB047337, CAB047338" Enhanced Enhanced "Plasma membrane" NA NA 130000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 44: Non-specific - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 45 "Plasma membrane" "CAB010898: , CAB047336: , CAB047337: , CAB047338: , HPA000263: , HPA011135: , HPA011227: " "unprognostic (2.17e-1)" "unprognostic (1.56e-1)" "unprognostic (9.72e-2)" "unprognostic (3.16e-2)" "unprognostic (2.03e-1)" "unprognostic (4.24e-2)" "unprognostic (1.31e-2)" "potential prognostic unfavorable (1.26e-5)" "unprognostic (1.18e-1)" "unprognostic (2.12e-1)" "validated prognostic favorable (2.34e-5)" "validated prognostic favorable (6.25e-4)" "unprognostic (2.52e-2)" "unprognostic (1.26e-2)" "unprognostic (9.30e-2)" "unprognostic (1.51e-1)" "unprognostic (4.99e-3)" "unprognostic (7.58e-3)" "unprognostic (1.43e-2)" "unprognostic (2.13e-1)" "unprognostic (5.60e-2)" "unprognostic (1.46e-2)" "unprognostic (1.28e-1)" "unprognostic (8.65e-2)" "unprognostic (3.77e-2)" "unprognostic (1.37e-1)" "unprognostic (3.18e-2)" "unprognostic (7.62e-3)" "unprognostic (7.70e-2)" "unprognostic (1.19e-1)" "unprognostic (2.03e-1)" MSR1 "CD204, SCARA1, SR-A, SR-AI, SR-AII, SR-AIII" ENSG00000038945 "Macrophage scavenger receptor 1" P21757 8 16107878-16567490 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Endocytosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "lung: 113.2" "Cell type enhanced" "Detected in many" "cDC: 188.4;Cone photoreceptor cells: 705.9;Distal convoluted tubule cells: 172.3;Kupffer cells: 1199.1;Macrophages: 671.3;Microglia: 172.5;monocytes: 291.8;Renal connecting tubule cells: 284.6" "Group enriched" "Detected in many" 7 "central nervous system macrophage: 282.4;upper rhombic lip: 274.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 16.8" "Lineage enriched" "Detected in many" 5 "monocytes: 16.8" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Lung - Macrophages, Pancreas - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Spleen - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid gland - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA000272, CAB032491" Enhanced NA NA 41000 "Cluster 40: Monocytes - Innate immune response" "Cluster 13: Lung - Secretion" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 9 "CAB032491: , HPA000272: " "unprognostic (1.63e-1)" "unprognostic (1.66e-2)" "unprognostic (3.29e-2)" "unprognostic (1.06e-3)" "unprognostic (4.04e-2)" "unprognostic (5.69e-2)" "unprognostic (4.12e-2)" "unprognostic (4.10e-2)" "unprognostic (8.65e-2)" "unprognostic (5.99e-2)" "unprognostic (2.57e-2)" "unprognostic (3.03e-1)" "unprognostic (3.56e-2)" "unprognostic (5.68e-3)" "unprognostic (1.96e-1)" "unprognostic (2.19e-2)" "unprognostic (2.33e-2)" "unprognostic (1.11e-2)" "unprognostic (4.45e-2)" "unprognostic (1.86e-2)" "potential prognostic unfavorable (8.07e-4)" "unprognostic (8.31e-2)" "unprognostic (1.57e-1)" "unprognostic (1.72e-1)" "unprognostic (2.86e-2)" "unprognostic (1.25e-2)" "unprognostic (3.41e-1)" "unprognostic (1.14e-1)" "unprognostic (4.40e-2)" "unprognostic (2.45e-1)" "unprognostic (1.45e-1)" MSRA ENSG00000175806 "Methionine sulfoxide reductase A" Q9UJ68 8 10054292-10428891 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 85.5;liver: 61.6" "Cell type enhanced" "Detected in many" "Astrocytes: 321.0;Bergmann glia: 499.2;Brain excitatory neurons: 929.3;Brain inhibitory neurons: 365.2;Choroid plexus epithelial cells: 316.1;Ependymal cells: 286.7;Late spermatids: 228.0;Oligodendrocyte progenitor cells: 371.9;Proximal tubule cells: 784.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 5.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023804, HPA053069, HPA075766" Approved Supported Nucleoplasm,Cytosol No No 40000 "Cluster 7: Non-specific - Innate immune response" "Cluster 72: Kidney - Transmembrane transport" "Cluster 35: Non-specific - DNA binding" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 7 "Nucleoplasm, Cytosol" "HPA023804: , HPA053069: , HPA075766: " "unprognostic (1.62e-2)" "unprognostic (4.79e-2)" "unprognostic (2.31e-2)" "unprognostic (2.67e-1)" "unprognostic (1.53e-1)" "unprognostic (9.63e-2)" "unprognostic (2.60e-2)" "unprognostic (1.78e-3)" "unprognostic (9.41e-2)" "unprognostic (4.23e-3)" "unprognostic (6.03e-3)" "potential prognostic favorable (5.73e-4)" "unprognostic (1.71e-1)" "unprognostic (8.14e-2)" "unprognostic (2.60e-1)" "unprognostic (4.43e-2)" "unprognostic (9.38e-2)" "unprognostic (1.68e-3)" "unprognostic (2.02e-1)" "unprognostic (8.87e-2)" "unprognostic (3.32e-2)" "unprognostic (4.65e-2)" "unprognostic (3.32e-2)" "unprognostic (1.11e-1)" "unprognostic (2.50e-2)" "unprognostic (1.88e-1)" "unprognostic (1.41e-1)" "unprognostic (3.39e-2)" "unprognostic (3.68e-1)" "unprognostic (1.02e-1)" MSRB1 "SELENOR, SELENOX, SelR, SelX, SepR, SEPX1" ENSG00000198736 "Methionine sulfoxide reductase B1" Q9NZV6 16 1938229-1943199 "Enzymes, Predicted intracellular proteins" "Immunity, Innate immunity" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 255.1" "Cell type enhanced" "Detected in many" "Epididymal efferent duct absorptive cells: 200.7;Esophageal apical cells: 254.6;Esophageal suprabasal cells: 141.6;Extravillous trophoblasts: 156.9;Hepatocytes: 289.9;Neutrophil progenitors: 228.1;Neutrophils: 492.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "eosinophil: 1424.3;neutrophil: 3078.4" "Lineage enriched" "Detected in all" 7 "granulocytes: 3078.4" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Neutrophils_2, Prostate - Smooth muscle cells, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008650, HPA043463, HPA069557" Enhanced Enhanced Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 19: Astrocytes - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 5 Nucleoplasm "CAB008650: , HPA043463: , HPA069557: " "unprognostic (1.86e-1)" "unprognostic (4.92e-3)" "unprognostic (2.15e-1)" "unprognostic (1.19e-1)" "unprognostic (1.29e-1)" "unprognostic (3.59e-2)" "unprognostic (1.17e-1)" "unprognostic (6.48e-2)" "unprognostic (2.67e-1)" "unprognostic (1.27e-2)" "unprognostic (1.75e-1)" "unprognostic (1.65e-2)" "unprognostic (1.15e-1)" "unprognostic (9.10e-2)" "unprognostic (1.11e-2)" "unprognostic (1.30e-1)" "unprognostic (2.21e-3)" "unprognostic (2.34e-1)" "unprognostic (3.31e-1)" "unprognostic (4.11e-2)" "unprognostic (3.02e-1)" "unprognostic (3.39e-1)" "unprognostic (2.20e-2)" "unprognostic (1.16e-1)" "unprognostic (5.31e-3)" "unprognostic (1.30e-1)" "unprognostic (1.33e-1)" "unprognostic (9.05e-2)" "unprognostic (6.70e-2)" MSRB2 "CBS-1, CBS1, CGI-131, MSRB, PILB" ENSG00000148450 "Methionine sulfoxide reductase B2" Q9Y3D2 10 23095579-23122013 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 230.9;Smooth muscle cells: 198.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Stomach - Fibroblasts, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027933 Enhanced "Intracellular and membrane" Enzyme NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 40: Non-specific - Unknown function" "Cluster 62: Smooth muscle cells - Muscle contraction" 13 "HPA027933: " "unprognostic (4.21e-1)" "unprognostic (5.02e-2)" "unprognostic (2.64e-1)" "unprognostic (3.00e-2)" "unprognostic (3.11e-1)" "unprognostic (9.92e-2)" "unprognostic (6.54e-2)" "potential prognostic favorable (5.57e-5)" "unprognostic (3.44e-3)" "unprognostic (1.87e-1)" "unprognostic (1.23e-2)" "unprognostic (4.71e-3)" "potential prognostic favorable (6.76e-4)" "unprognostic (1.22e-1)" "unprognostic (1.40e-2)" "unprognostic (7.50e-2)" "unprognostic (4.81e-2)" "unprognostic (1.31e-1)" "unprognostic (8.26e-3)" "unprognostic (4.99e-2)" "unprognostic (2.38e-2)" "unprognostic (9.86e-2)" "unprognostic (4.09e-2)" "unprognostic (1.65e-2)" "unprognostic (3.46e-2)" "unprognostic (1.37e-1)" "unprognostic (1.29e-1)" "unprognostic (1.53e-1)" "unprognostic (3.64e-2)" "unprognostic (5.90e-2)" "unprognostic (7.93e-2)" MSRB3 "DFNB74, DKFZp686C1178, FLJ36866" ENSG00000174099 "Methionine sulfoxide reductase B3" Q8IXL7 12 65278643-65491430 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 168.8" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 273.8;Cardiomyocytes: 309.4;Hematopoietic stem cells: 825.8;Hepatic stellate cells: 348.6;Lymphatic endothelial cells: 261.5;Myonuclei: 517.1;Neutrophil progenitors: 391.7;Peritubular myoid cells: 304.3;Podocytes: 353.3;Salivary myoepithelial cells: 449.0;Smooth muscle cells: 523.8;Vascular smooth muscle cells: 615.7" "Cell type enhanced" "Detected in all" "vascular associated smooth muscle cell: 777.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 41.8" "Lineage enhanced" "Detected in many" "granulocytes: 41.8" "Cancer enhanced" "Detected in all" "Rhabdoid: 95.9" "Adipose subcutaneous - Smooth muscle cells, Colon - Smooth muscle cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014432 Uncertain "Intracellular and membrane" Enzyme NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 44: Non-specific - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 62: Smooth muscle cells - Muscle contraction" 5 "HPA014432: " "unprognostic (1.04e-1)" "unprognostic (4.35e-2)" "unprognostic (3.54e-1)" "potential prognostic unfavorable (1.39e-5)" "unprognostic (7.57e-3)" "unprognostic (6.54e-2)" "unprognostic (2.06e-1)" "unprognostic (2.82e-1)" "unprognostic (1.60e-2)" "unprognostic (5.23e-2)" "unprognostic (1.62e-2)" "unprognostic (1.02e-2)" "unprognostic (1.54e-3)" "unprognostic (5.06e-3)" "unprognostic (3.40e-1)" "unprognostic (2.32e-1)" "unprognostic (1.02e-1)" "unprognostic (4.37e-2)" "unprognostic (1.16e-1)" "unprognostic (1.15e-2)" "unprognostic (2.91e-3)" "unprognostic (6.84e-2)" "unprognostic (1.80e-1)" "unprognostic (1.16e-1)" "unprognostic (5.94e-3)" "unprognostic (1.54e-2)" "unprognostic (4.38e-2)" "unprognostic (1.41e-3)" "unprognostic (4.96e-2)" "unprognostic (6.97e-3)" "unprognostic (1.17e-1)" MSS51 "FLJ39565, ZMYND17" ENSG00000166343 "MSS51 mitochondrial translational activator" Q4VC12 10 73423579-73433561 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skeletal muscle: 244.5" "Cell type enriched" "Detected in many" 7 "Myonuclei: 120.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA038564 Uncertain Vesicles,Cytosol NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 56: Non-specific - Sensory perception" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 19 Vesicles Cytosol "HPA038564: " "unprognostic (6.23e-2)" "potential prognostic favorable (2.59e-4)" "unprognostic (1.66e-1)" "unprognostic (1.12e-2)" "unprognostic (1.07e-2)" "unprognostic (2.89e-1)" "unprognostic (2.02e-1)" MST1 "D3F15S2, DNF15S2, HGFL, MSP, NF15S2" ENSG00000173531 "Macrophage stimulating 1" 3 49683947-49689501 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "liver: 864.2" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 358.7" "Cell type enhanced" "Detected in all" "astrocyte: 20.9" "Cancer enriched" "Detected in all" 6 "Liver Hepatocellular Carcinoma (TCGA): 182.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Kidney - Proximal tubular cells, Skeletal muscle - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA024036, HPA068514, CAB080358" Approved Approved Vesicles "Secreted to blood" NA NA "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 15: Non-specific - Transcription" "Cluster 18: Liver cancer - Metabolism" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 2 Vesicles "CAB080358: , HPA024036: , HPA068514: " "unprognostic (2.99e-2)" "unprognostic (8.42e-3)" "unprognostic (5.84e-2)" "unprognostic (3.55e-2)" "unprognostic (2.48e-1)" "unprognostic (7.89e-3)" "unprognostic (2.80e-1)" "unprognostic (1.50e-2)" "unprognostic (6.61e-3)" "unprognostic (1.22e-1)" "unprognostic (4.86e-3)" "unprognostic (1.20e-1)" "unprognostic (1.19e-2)" "unprognostic (1.43e-2)" "unprognostic (3.43e-2)" "unprognostic (1.93e-2)" "unprognostic (6.44e-2)" "unprognostic (4.73e-2)" "unprognostic (4.08e-2)" "unprognostic (1.94e-1)" "unprognostic (1.95e-1)" "unprognostic (4.89e-3)" "unprognostic (2.22e-1)" "unprognostic (2.89e-2)" "unprognostic (5.66e-2)" "unprognostic (1.56e-1)" "unprognostic (6.41e-2)" "unprognostic (4.77e-1)" "unprognostic (3.21e-1)" "unprognostic (1.82e-1)" "unprognostic (2.34e-1)" MST1R "CD136, CDw136, PTK8, RON, SEA" ENSG00000164078 "Macrophage stimulating 1 receptor" Q04912 3 49887002-49903873 "CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 18.2;skin 1: 30.2;stomach 1: 25.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 39.6;Colonocytes: 40.6;Conjunctival goblet cells: 24.3;Early spermatids: 33.2;Enterocytes: 33.5;Foveolar cells: 110.4;Goblet cells: 33.4;Mucous neck cells: 24.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 49.5" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Urothelial cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA007657, HPA008180, CAB008972" Enhanced Approved Cytosol NA NA "Cluster 77: Intestine - Digestion" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 68: Foveolar cells - Mucosal defense" 12 Cytosol "CAB008972: , HPA007657: , HPA008180: " "unprognostic (3.03e-1)" "unprognostic (2.38e-2)" "unprognostic (7.02e-3)" "unprognostic (1.29e-2)" "unprognostic (2.41e-1)" "unprognostic (8.94e-3)" "unprognostic (2.46e-1)" "unprognostic (2.14e-3)" "unprognostic (2.19e-2)" "unprognostic (1.12e-3)" "unprognostic (2.30e-2)" "unprognostic (5.05e-3)" "potential prognostic unfavorable (3.86e-5)" "unprognostic (3.71e-2)" "unprognostic (1.15e-3)" "unprognostic (3.64e-1)" "unprognostic (5.34e-1)" "unprognostic (2.13e-3)" "unprognostic (2.41e-1)" "unprognostic (1.30e-1)" "unprognostic (2.79e-1)" "unprognostic (8.07e-2)" "unprognostic (1.15e-1)" "unprognostic (2.08e-1)" "unprognostic (2.61e-1)" "potential prognostic favorable (6.59e-4)" "unprognostic (2.23e-2)" MSTN GDF8 ENSG00000138379 Myostatin O14793 2 190055700-190062729 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Cytokine, Growth factor, Heparin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "skeletal muscle: 9.4;tongue: 14.3" "Cell type enhanced" "Detected in some" "Adrenal cortex cells: 3.8;Bergmann glia: 5.8;Corticotrophs: 4.3;Early spermatids: 20.9;Late primary spermatocytes: 9.3;Late spermatids: 7.0;Müller glia: 14.6;Retinal bipolar cells: 4.6;Smooth muscle cells: 13.1;Thymic myoid cells: 17.7" "Cell type enhanced" "Detected in many" "Bergmann glia: 8.7" "Cancer enriched" "Detected in some" 6 "Glioblastoma Multiforme (TCGA): 9.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "Sarcoma: 18.2" "Colon - Enteric glia cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB009963 Approved "Secreted in other tissues" Cytokine NA NA 3100000 "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 31: Non-specific - Transcription" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 11: Muller glia cells - Retinal homeostasis" 18 "CAB009963: " "unprognostic (4.13e-2)" "validated prognostic favorable (6.28e-4)" "validated prognostic favorable (3.52e-4)" "unprognostic (4.78e-3)" MSTO1 "FLJ10504, LST005, misato, MST" ENSG00000125459 "Misato mitochondrial distribution and morphology regulator 1" Q9BUK6 1 155563235-155614951 "Disease related genes, Essential proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Late spermatids: 424.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005899, HPA005914, HPA006075" Approved Enhanced Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 70: Non-specific - Protein processing" "Cluster 45: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 5 Cytosol "HPA005899: , HPA005914: , HPA006075: " "potential prognostic unfavorable (8.17e-4)" "unprognostic (4.36e-3)" "unprognostic (4.59e-3)" "unprognostic (2.75e-2)" "unprognostic (6.96e-2)" "unprognostic (7.93e-2)" "unprognostic (1.69e-1)" "unprognostic (2.28e-3)" "unprognostic (5.38e-2)" "unprognostic (2.37e-1)" "unprognostic (4.96e-3)" "unprognostic (2.17e-2)" "unprognostic (1.00e-1)" "potential prognostic unfavorable (1.34e-5)" "unprognostic (1.52e-2)" "unprognostic (3.24e-2)" "unprognostic (1.53e-2)" "unprognostic (1.29e-1)" "unprognostic (1.03e-1)" "unprognostic (2.20e-1)" "unprognostic (4.15e-2)" "unprognostic (2.09e-1)" "potential prognostic unfavorable (3.43e-4)" "unprognostic (2.54e-2)" "unprognostic (2.12e-1)" "unprognostic (2.37e-1)" "unprognostic (1.45e-1)" "unprognostic (4.85e-2)" "unprognostic (2.24e-1)" "unprognostic (2.43e-1)" "unprognostic (1.51e-2)" MSX1 "HOX7, HYD1, OFC5" ENSG00000163132 "Msh homeobox 1" P28360 4 4859665-4863936 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "cervix: 49.4;choroid plexus: 140.3" "Group enriched" "Detected in many" 4 "Endometrial ciliated cells: 227.6;Endometrial glandular cells: 372.5;Endometrial luminal cells: 554.4;Endometrial secretory cells: 417.1" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 149.4;ependymal cell: 47.1" "Cancer enriched" "Detected in all" 16 "Uterine Corpus Endometrial Carcinoma (TCGA): 338.1" "Region enriched" "Detected in all" 9 "choroid plexus: 183.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 58.9" "Kidney - Endothelial cells, Pituitary gland - Thyrotropes, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB026198, HPA063895, HPA073604" Enhanced Supported Nucleoplasm NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 4 Nucleoplasm "CAB026198: , HPA063895: , HPA073604: " "unprognostic (7.08e-2)" "unprognostic (1.05e-1)" "unprognostic (2.56e-1)" "unprognostic (1.73e-1)" "unprognostic (1.73e-1)" "unprognostic (1.14e-2)" "unprognostic (5.21e-2)" "unprognostic (8.43e-2)" "unprognostic (5.99e-3)" "unprognostic (2.61e-2)" "unprognostic (6.90e-2)" "potential prognostic favorable (3.38e-4)" "unprognostic (4.86e-2)" "potential prognostic unfavorable (2.18e-4)" "unprognostic (4.20e-2)" "unprognostic (1.99e-2)" "unprognostic (2.07e-1)" "unprognostic (2.61e-3)" "unprognostic (8.28e-2)" "unprognostic (1.17e-1)" "unprognostic (1.43e-2)" "unprognostic (7.94e-2)" "unprognostic (1.75e-1)" "unprognostic (1.35e-1)" "unprognostic (1.31e-3)" "unprognostic (3.55e-2)" "unprognostic (1.71e-1)" "unprognostic (3.66e-3)" "unprognostic (2.00e-3)" MSX2 "CRS2, FPP, HOX8, MSH, PFM, PFM1" ENSG00000120149 "Msh homeobox 2" P35548 5 174724582-174730896 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Osteogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 24.2;placenta: 31.5;urinary bladder: 16.3" "Cell type enhanced" "Detected in many" "Bergmann glia: 63.4;Breast hormone-responsive cells: 36.6;Cytotrophoblasts: 198.8;Endometrial ciliated cells: 51.2;Endometrial glandular cells: 55.0;Endometrial luminal cells: 75.1;Migrating cytotrophoblasts: 116.0;Syncytiotrophoblasts: 263.3;Urothelial cells: 153.8" "Cell type enriched" "Detected in some" 11 "Bergmann glia: 73.9" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 33.2" "Group enriched" "Detected in many" 4 "cerebellum: 7.9;medulla oblongata: 15.6;pons: 5.2;spinal cord: 10.6;white matter: 10.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 64.1" "Breast - Breast glandular cells, Breast - Breast glandular cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Stomach - Gastric mucous cells, Testis - Sertoli cells" "Region enriched" "Detected in some" 5 "cerebellum: 6.2" "Low region specificity" "Detected in many" HPA005652 Uncertain Supported "Nuclear speckles" NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 43: Hindbrain - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 31 "Nuclear speckles" "HPA005652: " "unprognostic (2.91e-2)" "unprognostic (1.00e-2)" "unprognostic (9.03e-2)" "unprognostic (1.66e-1)" "unprognostic (2.92e-1)" "unprognostic (1.60e-2)" "unprognostic (1.08e-1)" "unprognostic (1.79e-1)" "potential prognostic unfavorable (6.70e-4)" "unprognostic (1.83e-2)" "potential prognostic unfavorable (6.89e-4)" "unprognostic (2.53e-2)" "unprognostic (3.65e-2)" "unprognostic (5.49e-2)" "unprognostic (1.92e-1)" "unprognostic (2.22e-3)" "unprognostic (6.22e-2)" "unprognostic (3.81e-2)" "unprognostic (2.29e-2)" "unprognostic (2.52e-1)" "unprognostic (8.58e-3)" "unprognostic (5.95e-2)" "unprognostic (2.22e-1)" "unprognostic (3.96e-2)" MT-ATP6 "ATP6, ATPase-6, MTATP6, RP, Su6m" ENSG00000198899 "Mitochondrially encoded ATP synthase membrane subunit 6" P00846 MT 8527-9207 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" "Cardiomyopathy, Disease variant, Leber hereditary optic neuropathy, Leigh syndrome, Neuropathy, Primary mitochondrial disease, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 240225.6" "Cell type enhanced" "Detected in many" "Pancreatic acinar cells: 31237.6;Retinal bipolar cells: 30657.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 15232.5" "Lineage enriched" "Detected in all" 6 "granulocytes: 15232.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 52: Non-specific - Cellular respiration" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 5 "unprognostic (1.23e-1)" "unprognostic (1.54e-1)" "unprognostic (6.27e-2)" "unprognostic (2.14e-2)" "unprognostic (1.04e-2)" "unprognostic (3.81e-2)" "unprognostic (2.02e-1)" "unprognostic (1.56e-1)" "unprognostic (3.25e-2)" "unprognostic (5.81e-3)" "unprognostic (7.77e-2)" "unprognostic (2.86e-3)" "unprognostic (1.04e-3)" "unprognostic (3.91e-2)" "unprognostic (6.06e-2)" "unprognostic (4.86e-2)" "unprognostic (7.69e-2)" "unprognostic (2.79e-2)" "unprognostic (2.02e-2)" "unprognostic (2.54e-3)" "unprognostic (5.42e-3)" "unprognostic (1.09e-1)" "unprognostic (8.57e-3)" "unprognostic (7.65e-2)" "potential prognostic favorable (2.00e-4)" "unprognostic (2.32e-1)" "unprognostic (4.73e-1)" "unprognostic (1.27e-1)" "unprognostic (4.25e-2)" MT-ATP8 "A6L, ATP8, MTATP8, URFA6L" ENSG00000228253 "Mitochondrially encoded ATP synthase membrane subunit 8" P03928 MT 8366-8572 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" "Cardiomyopathy, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 355486.2" "Cell type enhanced" "Detected in many" "Hepatocytes: 410.8;Pancreatic acinar cells: 304.1;Platelets: 317.0;Urothelial cells: 311.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "basophil: 10767.2" "Lineage enriched" "Detected in all" 6 "granulocytes: 10767.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 20: Non-specific - Transcription regulation" 11 "unprognostic (1.35e-2)" "unprognostic (1.47e-1)" "unprognostic (1.78e-1)" "unprognostic (2.78e-2)" "unprognostic (1.57e-1)" "unprognostic (1.90e-2)" "unprognostic (1.39e-1)" "unprognostic (1.41e-1)" "unprognostic (9.50e-2)" "unprognostic (6.22e-3)" "unprognostic (2.24e-1)" "unprognostic (3.58e-2)" "unprognostic (1.41e-3)" "unprognostic (4.36e-2)" "unprognostic (8.19e-2)" "unprognostic (1.30e-2)" "unprognostic (2.44e-2)" "unprognostic (9.75e-3)" "unprognostic (1.32e-1)" "unprognostic (4.18e-2)" "unprognostic (1.46e-2)" "unprognostic (4.59e-2)" "unprognostic (3.67e-2)" "unprognostic (3.82e-2)" "unprognostic (2.01e-1)" "unprognostic (8.28e-3)" "unprognostic (2.91e-1)" "unprognostic (1.65e-1)" "unprognostic (1.20e-2)" MT-CO1 "COI, COX1, MTCO1" ENSG00000198804 "Mitochondrially encoded cytochrome c oxidase I" P00395 MT 5904-7445 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Electron transport, Respiratory chain, Transport" Translocase "Deafness, Disease variant, Leber hereditary optic neuropathy, Non-syndromic deafness, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 265338.6;tongue: 172333.2" "Cell type enhanced" "Detected in many" "Colonocytes: 61581.5;Enterocytes: 89897.0;Hepatocytes: 54246.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016241, HPA069328" Enhanced Supported "Mitochondria,End piece" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 52: Non-specific - Cellular respiration" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 1: Enterocytes - Absorption and Digestion" 12 Mitochondria "End piece" "CAB016241: , HPA069328: " "unprognostic (2.64e-1)" "unprognostic (6.46e-2)" "unprognostic (2.95e-2)" "unprognostic (5.03e-2)" "unprognostic (4.75e-3)" "unprognostic (2.29e-1)" "unprognostic (6.30e-2)" "unprognostic (1.93e-1)" "potential prognostic favorable (4.32e-5)" "unprognostic (3.13e-2)" "unprognostic (3.25e-2)" "unprognostic (1.14e-1)" "potential prognostic favorable (6.61e-5)" "unprognostic (8.70e-2)" "unprognostic (6.54e-2)" "unprognostic (4.12e-1)" "unprognostic (7.51e-3)" "unprognostic (1.18e-2)" "unprognostic (5.42e-2)" "unprognostic (1.12e-2)" "unprognostic (2.39e-2)" "unprognostic (8.85e-2)" "unprognostic (4.35e-1)" "unprognostic (1.65e-1)" "unprognostic (3.15e-2)" "unprognostic (2.07e-2)" "unprognostic (2.55e-1)" "unprognostic (8.59e-3)" "unprognostic (1.86e-3)" MT-CO2 "CO2, COX2, MTCO2" ENSG00000198712 "Mitochondrially encoded cytochrome c oxidase II" P00403 MT 7586-8269 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Electron transport, Respiratory chain, Transport" Translocase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 214510.8" "Cell type enhanced" "Detected in many" "Colonocytes: 40015.1;Enterocytes: 36306.9;Hepatocytes: 57294.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016243, HPA051505, HPA054758" Enhanced NA NA 440000 "Cluster 22: Eosinophils - Transcription" "Cluster 52: Non-specific - Cellular respiration" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 35 "CAB016243: , HPA051505: , HPA054758: " "unprognostic (3.98e-1)" "unprognostic (3.46e-2)" "unprognostic (3.64e-2)" "unprognostic (1.65e-2)" "unprognostic (9.32e-2)" "unprognostic (9.78e-2)" "unprognostic (6.89e-2)" "unprognostic (3.83e-2)" "unprognostic (5.86e-3)" "potential prognostic unfavorable (8.72e-4)" "unprognostic (1.24e-1)" "unprognostic (1.13e-1)" "unprognostic (1.30e-3)" "unprognostic (1.22e-2)" "unprognostic (1.21e-1)" "unprognostic (1.24e-2)" "unprognostic (3.58e-2)" "unprognostic (3.41e-3)" "unprognostic (3.01e-2)" "potential prognostic favorable (1.22e-4)" "unprognostic (1.31e-2)" "unprognostic (7.16e-2)" "unprognostic (4.83e-2)" "unprognostic (5.88e-2)" "unprognostic (9.52e-2)" "unprognostic (1.61e-1)" "unprognostic (4.74e-1)" "unprognostic (4.45e-2)" "unprognostic (1.02e-3)" MT-CO3 "CO3, COIII, COX3, MTCO3" ENSG00000198938 "Mitochondrially encoded cytochrome c oxidase III" P00414 MT 9207-9990 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Translocase "Disease variant, Leber hereditary optic neuropathy, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 238539.3" "Cell type enhanced" "Detected in many" "Colonocytes: 44370.7;Enterocytes: 42681.8;Hepatocytes: 48547.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042788 Approved NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 52: Non-specific - Cellular respiration" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 1 "HPA042788: " "unprognostic (9.10e-2)" "unprognostic (7.30e-2)" "unprognostic (1.26e-2)" "unprognostic (8.34e-2)" "unprognostic (4.79e-3)" "unprognostic (2.22e-1)" "unprognostic (1.55e-1)" "unprognostic (2.41e-1)" "potential prognostic favorable (7.95e-5)" "unprognostic (4.53e-2)" "unprognostic (1.18e-1)" "unprognostic (9.69e-2)" "potential prognostic favorable (3.70e-4)" "unprognostic (2.51e-2)" "unprognostic (8.01e-2)" "unprognostic (2.19e-2)" "unprognostic (2.56e-2)" "unprognostic (2.84e-2)" "unprognostic (3.89e-2)" "potential prognostic favorable (3.25e-4)" "unprognostic (7.01e-2)" "unprognostic (7.92e-2)" "unprognostic (2.47e-2)" "unprognostic (2.08e-1)" "unprognostic (1.43e-3)" "unprognostic (2.58e-3)" "unprognostic (4.10e-1)" "unprognostic (1.19e-2)" "unprognostic (2.69e-2)" MT-CYB "COB, CYTB, MTCYB, UQCR3" ENSG00000198727 "Mitochondrially encoded cytochrome b" P00156 MT 14747-15887 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Cardiomyopathy, Cataract, Deafness, Disease variant, Leber hereditary optic neuropathy, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 131222.4" "Cell type enhanced" "Detected in many" "Enterocytes: 23189.4;Pancreatic acinar cells: 24886.2;Retinal bipolar cells: 27394.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032215, HPA068400, HPA074796" Approved Supported Mitochondria NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 52: Non-specific - Cellular respiration" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 3 Mitochondria "CAB032215: , HPA068400: , HPA074796: " "potential prognostic favorable (6.90e-4)" "unprognostic (1.16e-1)" "unprognostic (1.83e-1)" "unprognostic (1.19e-1)" "unprognostic (2.04e-2)" "unprognostic (1.18e-1)" "unprognostic (2.77e-1)" "unprognostic (1.24e-1)" "unprognostic (1.19e-3)" "unprognostic (5.82e-3)" "unprognostic (5.50e-2)" "unprognostic (3.92e-3)" "potential prognostic favorable (6.45e-4)" "unprognostic (1.34e-1)" "unprognostic (5.48e-2)" "unprognostic (6.53e-2)" "unprognostic (9.93e-2)" "unprognostic (1.06e-2)" "unprognostic (8.29e-2)" "potential prognostic favorable (7.74e-4)" "unprognostic (8.06e-3)" "unprognostic (5.88e-2)" "unprognostic (1.00e-1)" "unprognostic (3.35e-2)" "unprognostic (1.88e-1)" "unprognostic (3.53e-3)" "unprognostic (2.92e-1)" "unprognostic (2.78e-2)" "unprognostic (7.09e-2)" MT-ND1 "MTND1, NAD1, ND1" ENSG00000198888 "Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1" P03886 MT 3307-4262 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" Translocase "Alzheimer disease, Amyloidosis, Diabetes mellitus, Disease variant, Epilepsy, FDA approved drug targets, Leber hereditary optic neuropathy, MELAS syndrome, Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 129323.4" "Cell type enhanced" "Detected in many" "Colonocytes: 18499.9;Enterocytes: 16662.0;Goblet cells: 14766.0;Hepatocytes: 14992.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 9528.1" "Lineage enriched" "Detected in all" 7 "granulocytes: 9528.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033779, HPA066847" Approved NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 16 "CAB033779: , HPA066847: " "unprognostic (2.68e-2)" "unprognostic (5.32e-3)" "unprognostic (1.23e-1)" "unprognostic (2.30e-1)" "unprognostic (3.39e-1)" "unprognostic (2.60e-1)" "unprognostic (4.40e-2)" "unprognostic (1.95e-1)" "potential prognostic favorable (7.45e-6)" "unprognostic (2.80e-2)" "unprognostic (1.83e-1)" "unprognostic (1.63e-2)" "unprognostic (1.06e-2)" "unprognostic (3.20e-1)" "unprognostic (4.50e-2)" "unprognostic (3.56e-2)" "unprognostic (1.69e-3)" "unprognostic (1.02e-1)" "unprognostic (5.44e-2)" "unprognostic (2.75e-3)" "unprognostic (1.08e-3)" "unprognostic (8.12e-2)" "unprognostic (1.77e-3)" "unprognostic (4.31e-2)" "unprognostic (2.19e-1)" "unprognostic (8.74e-2)" "unprognostic (1.08e-1)" "unprognostic (7.60e-2)" "unprognostic (4.55e-3)" MT-ND2 "MTND2, NAD2, ND2" ENSG00000198763 "Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2" P03891 MT 4470-5511 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" Translocase "Alzheimer disease, Amyloidosis, Disease variant, Leber hereditary optic neuropathy, Leigh syndrome, Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 107283.0;heart muscle: 130852.9" "Cell type enhanced" "Detected in many" "Colonocytes: 18264.0;Enteric stem cells: 14079.5;Enterocytes: 32456.0;Goblet cells: 16907.8;Hepatocytes: 16745.9;Paneth cells: 15546.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 6 "basophil: 16897.8" "Lineage enriched" "Detected in all" 10 "granulocytes: 16897.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 52: Non-specific - Cellular respiration" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 1: Enterocytes - Absorption and Digestion" 4 "unprognostic (1.53e-1)" "unprognostic (1.06e-1)" "unprognostic (1.60e-1)" "potential prognostic unfavorable (4.47e-4)" "unprognostic (9.19e-2)" "unprognostic (3.35e-1)" "unprognostic (2.70e-1)" "unprognostic (5.05e-2)" "potential prognostic favorable (8.78e-4)" "potential prognostic unfavorable (8.19e-4)" "unprognostic (3.17e-1)" "unprognostic (7.90e-2)" "unprognostic (2.08e-2)" "unprognostic (2.48e-2)" "unprognostic (9.88e-2)" "unprognostic (4.88e-2)" "unprognostic (4.37e-2)" "unprognostic (1.47e-2)" "unprognostic (1.18e-1)" "unprognostic (2.30e-2)" "unprognostic (3.26e-3)" "unprognostic (1.23e-2)" "unprognostic (2.69e-2)" "unprognostic (1.43e-2)" "unprognostic (3.91e-2)" "unprognostic (3.37e-2)" "unprognostic (3.28e-1)" "unprognostic (3.36e-2)" "unprognostic (1.28e-2)" MT-ND3 "MTND3, NAD3, ND3" ENSG00000198840 "Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3" P03897 MT 10059-10404 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" Translocase "Disease variant, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 186829.7" "Cell type enhanced" "Detected in many" "Enterocytes: 21790.2;Hepatocytes: 22175.9;Pancreatic acinar cells: 31598.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063296 Enhanced Uncertain Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 52: Non-specific - Cellular respiration" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 1 Cytosol "HPA063296: " "unprognostic (1.23e-1)" "unprognostic (1.53e-1)" "unprognostic (1.42e-1)" "unprognostic (1.93e-1)" "unprognostic (3.89e-1)" "unprognostic (1.38e-1)" "unprognostic (1.31e-2)" "unprognostic (8.66e-2)" "unprognostic (4.98e-2)" "unprognostic (1.33e-2)" "unprognostic (4.68e-2)" "unprognostic (5.55e-3)" "unprognostic (1.23e-3)" "unprognostic (3.57e-2)" "unprognostic (1.71e-2)" "unprognostic (2.19e-2)" "unprognostic (1.93e-1)" "unprognostic (2.39e-1)" "unprognostic (4.69e-1)" "unprognostic (3.73e-3)" "unprognostic (3.86e-2)" "unprognostic (1.88e-1)" "unprognostic (1.15e-1)" "unprognostic (3.50e-3)" "unprognostic (5.93e-2)" "unprognostic (1.39e-1)" "unprognostic (1.43e-1)" "unprognostic (5.33e-2)" "unprognostic (7.95e-2)" MT-ND4 "LHON, MTND4, NAD4, ND4" ENSG00000198886 "Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4" P03905 MT 10760-12137 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" Translocase "Disease variant, Dystonia, Leber hereditary optic neuropathy, MELAS syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 197808.9" "Cell type enhanced" "Detected in many" "Colonocytes: 31374.9;Enterocytes: 26409.8;Hepatocytes: 36703.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 13564.4" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053928 Approved Approved Mitochondria NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 52: Non-specific - Cellular respiration" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 20 Mitochondria "HPA053928: " "unprognostic (1.08e-1)" "unprognostic (3.45e-2)" "unprognostic (7.62e-2)" "unprognostic (4.58e-2)" "unprognostic (7.24e-2)" "unprognostic (1.36e-1)" "unprognostic (1.42e-1)" "unprognostic (7.67e-2)" "potential prognostic favorable (1.08e-4)" "potential prognostic unfavorable (4.76e-5)" "unprognostic (6.43e-2)" "unprognostic (1.51e-2)" "potential prognostic favorable (9.94e-4)" "unprognostic (1.04e-1)" "unprognostic (1.79e-1)" "unprognostic (5.60e-2)" "unprognostic (5.13e-2)" "unprognostic (4.26e-2)" "unprognostic (8.24e-3)" "unprognostic (1.19e-2)" "unprognostic (1.65e-3)" "unprognostic (1.23e-1)" "unprognostic (7.87e-2)" "unprognostic (1.28e-1)" "unprognostic (1.02e-1)" "unprognostic (7.61e-2)" "unprognostic (2.92e-1)" "unprognostic (1.37e-2)" "unprognostic (2.62e-2)" MT-ND4L "MTND4L, NAD4L, ND4L" ENSG00000212907 "Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4L" P03901 MT 10470-10766 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" Translocase "Disease variant, Leber hereditary optic neuropathy, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 149995.1;tongue: 96029.4" "Cell type enhanced" "Detected in many" "Hepatocytes: 3652.1;Urothelial cells: 1473.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075648 Approved Centrosome,Mitochondria,Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 52: Non-specific - Cellular respiration" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 69: Urothelial cells - Basic cellular functions" Mitochondria "Centrosome, Cytosol" "HPA075648: " "unprognostic (2.89e-2)" "unprognostic (9.45e-2)" "unprognostic (4.06e-2)" "unprognostic (2.34e-1)" "unprognostic (1.31e-1)" "unprognostic (2.85e-2)" "unprognostic (2.23e-1)" "unprognostic (1.32e-1)" "unprognostic (3.14e-3)" "potential prognostic unfavorable (1.66e-4)" "unprognostic (1.09e-1)" "unprognostic (1.62e-1)" "unprognostic (6.71e-3)" "unprognostic (1.64e-1)" "unprognostic (7.57e-3)" "unprognostic (1.32e-2)" "unprognostic (2.26e-2)" "unprognostic (5.10e-3)" "unprognostic (1.89e-1)" "unprognostic (3.65e-2)" "unprognostic (1.41e-3)" "unprognostic (1.48e-2)" "unprognostic (2.60e-1)" "unprognostic (2.17e-1)" "unprognostic (5.55e-2)" "unprognostic (3.69e-2)" "unprognostic (3.79e-1)" "unprognostic (6.22e-3)" "unprognostic (2.39e-3)" MT-ND5 "MTND5, NAD5, ND5" ENSG00000198786 "Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5" P03915 MT 12337-14148 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" Translocase "Disease variant, Leber hereditary optic neuropathy, Leigh syndrome, MELAS syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 26164.9;skeletal muscle: 24072.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 6724.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 52: Non-specific - Cellular respiration" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 17 "unprognostic (1.69e-3)" "unprognostic (1.00e-1)" "unprognostic (2.76e-2)" "unprognostic (1.94e-1)" "unprognostic (4.37e-3)" "unprognostic (3.87e-2)" "unprognostic (8.29e-2)" "unprognostic (1.34e-1)" "unprognostic (2.86e-3)" "unprognostic (3.61e-2)" "potential prognostic favorable (7.10e-4)" "potential prognostic favorable (1.36e-4)" "unprognostic (1.76e-3)" "unprognostic (2.17e-3)" "unprognostic (4.19e-2)" "unprognostic (2.30e-1)" "unprognostic (7.60e-2)" "unprognostic (1.09e-1)" "unprognostic (2.14e-1)" "unprognostic (3.77e-3)" "unprognostic (1.96e-3)" "unprognostic (1.02e-1)" "unprognostic (2.49e-1)" "unprognostic (3.03e-2)" "unprognostic (3.94e-2)" "unprognostic (4.77e-2)" "unprognostic (1.58e-1)" "unprognostic (1.64e-2)" "unprognostic (2.21e-2)" MT-ND6 "MTND6, NAD6, ND6" ENSG00000198695 "Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6" P03923 MT 14149-14673 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" Translocase "Disease variant, Dystonia, Leber hereditary optic neuropathy, Leigh syndrome, MELAS syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 33513.0;skeletal muscle: 54270.6" "Cell type enhanced" "Detected in many" "Hepatocytes: 559.9;Retinal bipolar cells: 384.7;Retinal horizontal cells: 406.7;Rod photoreceptor cells: 307.6" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 31.6;vascular associated smooth muscle cell: 32.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 1 "unprognostic (3.59e-2)" "unprognostic (3.49e-1)" "unprognostic (8.42e-2)" "unprognostic (8.71e-2)" "unprognostic (3.48e-2)" "unprognostic (1.65e-1)" "unprognostic (8.58e-2)" "unprognostic (1.81e-2)" "unprognostic (8.99e-2)" "unprognostic (1.11e-2)" "potential prognostic favorable (1.32e-4)" "unprognostic (1.38e-3)" "unprognostic (2.14e-3)" "unprognostic (4.63e-3)" "unprognostic (1.26e-1)" "unprognostic (1.79e-1)" "unprognostic (2.85e-1)" "unprognostic (1.97e-1)" "unprognostic (1.03e-1)" "unprognostic (1.50e-2)" "unprognostic (2.90e-3)" "unprognostic (1.39e-1)" "unprognostic (1.05e-1)" "unprognostic (5.39e-3)" "unprognostic (6.44e-2)" "unprognostic (1.08e-1)" "unprognostic (5.66e-2)" "unprognostic (2.11e-2)" "unprognostic (4.56e-2)" MT1A "MT1, MT1S" ENSG00000205362 "Metallothionein 1A" P04731 16 56638666-56640087 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 475.7;liver: 400.5" "Group enriched" "Detected in many" 4 "Epididymal efferent duct ciliated cells: 257.3;Hepatocytes: 311.9;Pericytes: 539.9;Vascular smooth muscle cells: 1000.0" "Cell type enhanced" "Detected in some" "astrocyte: 2.4;ependymal cell: 2.2;vascular associated smooth muscle cell: 7.5" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 84.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Colon - Neutrophils, Liver - Neutrophils" "CAB002161, CAB013056" Approved NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 103: Non-specific - Basic cellular processes" 2 "CAB002161: , CAB013056: " "potential prognostic unfavorable (9.85e-4)" "unprognostic (3.03e-2)" "unprognostic (9.25e-2)" "unprognostic (1.97e-1)" "unprognostic (2.97e-2)" "unprognostic (4.60e-2)" "validated prognostic unfavorable (7.74e-4)" "validated prognostic unfavorable (2.58e-5)" "unprognostic (7.08e-2)" "unprognostic (6.79e-2)" "unprognostic (9.91e-2)" "unprognostic (1.30e-2)" "unprognostic (4.26e-1)" "unprognostic (9.71e-2)" "unprognostic (4.59e-1)" "unprognostic (3.76e-2)" "unprognostic (1.86e-1)" "unprognostic (1.64e-2)" "unprognostic (4.68e-2)" "unprognostic (6.99e-2)" "unprognostic (5.22e-1)" "unprognostic (3.25e-1)" "unprognostic (1.14e-1)" "unprognostic (9.22e-2)" "unprognostic (2.89e-1)" "unprognostic (9.37e-3)" "unprognostic (4.51e-1)" "unprognostic (4.38e-2)" "unprognostic (3.89e-1)" "unprognostic (9.36e-2)" "potential prognostic unfavorable (5.46e-5)" MT1B "MT1, MT1Q" ENSG00000169688 "Metallothionein 1B" P07438 16 56651886-56653204 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "liver: 19.5" "Cell type enhanced" "Detected in some" "Endometrial luminal cells: 1.8;Enterocytes: 3.4;Epididymal efferent duct ciliated cells: 2.9;Extravillous trophoblasts: 5.5;Hepatocytes: 15.3;Neutrophils: 8.5" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 166 "Liver Hepatocellular Carcinoma (TCGA): 110.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 5 "unprognostic (1.74e-1)" "unprognostic (9.81e-3)" MT1E "MT1, MTD" ENSG00000169715 "Metallothionein 1E" P04732 16 56625475-56627112 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1743.4" "Cell type enhanced" "Detected in many" "Colonocytes: 3162.8;Endometrial luminal cells: 2689.4;Enteric stem cells: 2105.1;Enteric transient amplifying cells: 2686.0;Enterocytes: 4972.0;Epididymal efferent duct absorptive cells: 3075.1;Epididymal efferent duct ciliated cells: 2800.3;Gastric chief cells: 6249.8;Goblet cells: 1924.5;Hepatocytes: 3961.7;Paneth cells: 2216.0;Parietal cells: 1921.7" "Cell type enhanced" "Detected in many" "astrocyte: 208.0;endothelial cell: 221.8;ependymal cell: 136.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "dendritic cells: 5.9;T-cells: 21.1" "Low cancer specificity" "Detected in many" "Spleen - Fibroblasts_2" HPA041152 Approved Approved Nucleoplasm NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 70: Non-specific - Protein processing" "Cluster 19: Astrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" Nucleoplasm "HPA041152: " "unprognostic (3.80e-1)" "unprognostic (4.98e-2)" "unprognostic (2.68e-2)" "unprognostic (7.61e-2)" "unprognostic (2.20e-1)" "unprognostic (2.56e-1)" "unprognostic (1.14e-2)" "potential prognostic unfavorable (4.03e-4)" "unprognostic (7.00e-3)" "unprognostic (2.66e-2)" "potential prognostic unfavorable (7.10e-5)" "unprognostic (9.24e-2)" "unprognostic (1.32e-2)" "unprognostic (3.60e-1)" "unprognostic (6.19e-3)" "unprognostic (2.56e-1)" "unprognostic (3.38e-2)" "unprognostic (3.45e-2)" "unprognostic (3.03e-1)" "unprognostic (6.65e-2)" "unprognostic (2.98e-2)" "potential prognostic unfavorable (5.74e-4)" "unprognostic (1.96e-1)" "unprognostic (2.74e-1)" "unprognostic (4.49e-2)" "unprognostic (1.13e-2)" "unprognostic (1.82e-1)" "unprognostic (2.64e-1)" "unprognostic (1.13e-1)" "unprognostic (1.20e-1)" "unprognostic (5.03e-3)" MT1F MT1 ENSG00000198417 "Metallothionein 1F" P04733 16 56657731-56660698 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 661.3;liver: 1026.8;thyroid gland: 1106.9" "Cell type enhanced" "Detected in many" "Colonocytes: 789.9;Endometrial glandular cells: 708.9;Endometrial luminal cells: 1589.2;Enteric stem cells: 682.3;Enteric transient amplifying cells: 733.7;Enterocytes: 1816.9;Epididymal efferent duct absorptive cells: 1681.2;Epididymal efferent duct ciliated cells: 690.0;Extravillous trophoblasts: 572.3;Gastric chief cells: 2657.0;Hepatocytes: 1277.2;Paneth cells: 924.3;Parietal cells: 1175.7" "Group enriched" "Detected in many" 5 "astrocyte: 39.9;endothelial cell: 66.4;ependymal cell: 76.1" "Cancer enhanced" "Detected in all" "Thyroid Carcinoma (TCGA): 702.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 56.0;classical monocyte: 30.3;gdT-cell: 47.1;MAIT T-cell: 41.9;memory B-cell: 25.8;memory CD4 T-cell: 49.1;memory CD8 T-cell: 80.3;naive CD4 T-cell: 49.6;naive CD8 T-cell: 85.8;T-reg: 89.5" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Uterine cancer: 93.0" "Adrenal gland - Adrenal cortex cells, Prostate - Prostate glandular cells, Stomach - Chief cells, Thyroid gland - Thyroid glandular cells" NA NA 240000 "Cluster 11: T-cells - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 1 "unprognostic (4.88e-2)" "unprognostic (2.70e-1)" "unprognostic (1.67e-3)" "unprognostic (2.30e-1)" "unprognostic (2.81e-1)" "unprognostic (8.68e-2)" "validated prognostic unfavorable (5.69e-4)" "validated prognostic unfavorable (1.01e-4)" "potential prognostic unfavorable (4.86e-4)" "unprognostic (2.28e-1)" "potential prognostic unfavorable (3.49e-4)" "unprognostic (1.50e-1)" "unprognostic (1.80e-2)" "unprognostic (1.82e-1)" "unprognostic (1.69e-1)" "unprognostic (1.97e-1)" "unprognostic (3.81e-2)" "unprognostic (6.43e-3)" "unprognostic (3.02e-1)" "unprognostic (7.72e-2)" "unprognostic (1.60e-1)" "unprognostic (1.45e-1)" "unprognostic (7.74e-3)" "unprognostic (4.01e-1)" "unprognostic (6.00e-2)" "unprognostic (1.18e-2)" "unprognostic (1.27e-1)" "unprognostic (6.40e-2)" "unprognostic (1.00e-1)" "unprognostic (7.90e-3)" "unprognostic (4.59e-3)" MT1G "MT1, MT1K" ENSG00000125144 "Metallothionein 1G" P13640 16 56666730-56668065 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 3503.8;liver: 6501.2;thyroid gland: 2684.8" "Cell type enhanced" "Detected in many" "Colonocytes: 4913.8;Endometrial glandular cells: 5018.4;Endometrial luminal cells: 16037.4;Enterocytes: 7693.5;Epididymal efferent duct absorptive cells: 7259.6;Gastric chief cells: 24750.3;Hepatocytes: 16899.1;Pancreatic acinar cells: 3536.0;Paneth cells: 3275.7;Parietal cells: 9513.1" "Group enriched" "Detected in many" 4 "astrocyte: 63.2;endothelial cell: 35.8;ependymal cell: 61.4" "Cancer enhanced" "Detected in all" "Thyroid Carcinoma (TCGA): 1716.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 163.9;colorectal cancer: 107.7;Leukemia: 117.7" "Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Prostate glandular cells, Stomach - Chief cells" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 76: Non-specific - Metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 3 "unprognostic (2.46e-2)" "unprognostic (3.77e-2)" "unprognostic (1.31e-1)" "unprognostic (2.25e-2)" "unprognostic (1.25e-1)" "unprognostic (1.63e-1)" "validated prognostic unfavorable (3.05e-4)" "validated prognostic unfavorable (7.89e-4)" "unprognostic (1.61e-2)" "unprognostic (4.91e-2)" "potential prognostic unfavorable (4.55e-4)" "unprognostic (2.40e-2)" "unprognostic (1.33e-1)" "unprognostic (1.11e-1)" "unprognostic (5.37e-3)" "unprognostic (1.02e-1)" "unprognostic (5.68e-2)" "unprognostic (2.85e-1)" "unprognostic (1.23e-1)" "unprognostic (2.29e-1)" "unprognostic (8.04e-2)" "unprognostic (2.02e-2)" "unprognostic (3.22e-1)" "unprognostic (2.21e-1)" "unprognostic (3.29e-1)" "unprognostic (5.30e-3)" "unprognostic (3.21e-2)" "unprognostic (1.18e-1)" "unprognostic (4.70e-2)" "unprognostic (3.58e-2)" "unprognostic (5.09e-3)" MT1H MT1 ENSG00000205358 "Metallothionein 1H" P80294 16 56669814-56671129 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 853.0;liver: 1081.3" "Cell type enhanced" "Detected in many" "Colonocytes: 965.7;Endometrial glandular cells: 807.5;Endometrial luminal cells: 3833.5;Enteric transient amplifying cells: 802.8;Enterocytes: 2949.4;Epididymal efferent duct absorptive cells: 1325.4;Extravillous trophoblasts: 827.2;Gastric chief cells: 1371.6;Hepatocytes: 3263.1;Pancreatic acinar cells: 967.6;Paneth cells: 642.0" "Group enriched" "Detected in some" 8 "astrocyte: 7.2;choroid plexus epithelial cell: 3.4;endothelial cell: 2.3;ependymal cell: 8.0" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 537.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 17.2;Myeloma: 12.0" "Kidney - Proximal tubular cells" NA NA "Cluster 76: Non-specific - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 3 "unprognostic (3.14e-2)" "unprognostic (8.59e-2)" "unprognostic (2.27e-1)" "unprognostic (4.75e-3)" "unprognostic (1.17e-1)" "unprognostic (1.07e-1)" "potential prognostic unfavorable (7.51e-7)" "unprognostic (3.96e-3)" "unprognostic (2.49e-2)" "unprognostic (4.14e-3)" "unprognostic (5.46e-2)" "unprognostic (1.03e-1)" "unprognostic (2.84e-2)" "unprognostic (1.46e-2)" "unprognostic (4.64e-2)" "unprognostic (6.62e-2)" "unprognostic (3.11e-1)" "unprognostic (2.57e-1)" "unprognostic (2.37e-1)" "unprognostic (7.40e-3)" "unprognostic (3.51e-3)" "unprognostic (1.98e-1)" "unprognostic (2.28e-1)" "unprognostic (2.28e-1)" "unprognostic (2.06e-3)" "unprognostic (7.24e-2)" "unprognostic (4.45e-2)" "unprognostic (4.06e-2)" "unprognostic (5.85e-2)" "unprognostic (1.01e-2)" MT1HL1 MT1P2 ENSG00000244020 "Metallothionein 1H like 1" P0DM35 1 237004103-237004441 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "heart muscle: 5.5;kidney: 1.0;liver: 1.4" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 2.7;Endometrial luminal cells: 3.5;Hepatocytes: 1.4;Parietal cells: 1.8;Proximal tubule cells: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes" NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" MT1M "MT1, MT1K" ENSG00000205364 "Metallothionein 1M" Q8N339 16 56632659-56633981 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 989.3;liver: 1516.9" "Cell type enhanced" "Detected in many" "Colonocytes: 899.8;Endometrial glandular cells: 715.6;Endometrial luminal cells: 2055.1;Enteric transient amplifying cells: 463.9;Enterocytes: 815.3;Epididymal efferent duct absorptive cells: 585.9;Epididymal efferent duct ciliated cells: 607.3;Gastric chief cells: 1459.0;Hepatocytes: 1383.2;Myosatellite cells: 590.6;Parietal cells: 556.9;Pericytes: 547.2;Schwann cells: 476.6;Vascular smooth muscle cells: 1147.3" "Cell type enhanced" "Detected in many" "astrocyte: 116.1;endothelial cell: 84.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 25.3;ovarian cancer: 27.8" "Colon - Neutrophils, Skin - Macrophages" NA NA "Cluster 70: Non-specific - Protein processing" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 103: Non-specific - Basic cellular processes" 7 "unprognostic (2.25e-1)" "unprognostic (8.08e-2)" "unprognostic (2.52e-2)" "unprognostic (1.83e-1)" "unprognostic (4.09e-1)" "unprognostic (8.31e-2)" "validated prognostic unfavorable (7.59e-4)" "validated prognostic unfavorable (4.43e-6)" "unprognostic (3.12e-2)" "unprognostic (4.66e-1)" "unprognostic (1.72e-1)" "unprognostic (1.03e-1)" "unprognostic (2.51e-2)" "unprognostic (2.09e-1)" "unprognostic (1.29e-1)" "unprognostic (7.20e-2)" "unprognostic (3.39e-1)" "unprognostic (1.81e-1)" "unprognostic (9.01e-2)" "unprognostic (1.59e-1)" "unprognostic (3.65e-1)" "unprognostic (1.88e-1)" "unprognostic (2.10e-2)" "unprognostic (3.39e-1)" "unprognostic (3.98e-2)" "unprognostic (3.52e-3)" "potential prognostic unfavorable (9.24e-4)" "unprognostic (1.12e-1)" "unprognostic (7.41e-2)" "unprognostic (3.73e-3)" "potential prognostic unfavorable (6.27e-4)" MT1X "MT-1l, MT1" ENSG00000187193 "Metallothionein 1X" P80297 16 56682470-56684196 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 4654.0;skeletal muscle: 7048.3" "Cell type enhanced" "Detected in many" "Enterocytes: 2166.1;Epididymal basal cells: 1477.4;Epididymal efferent duct absorptive cells: 1749.3;Epididymal efferent duct ciliated cells: 1270.4;Esophageal basal cells: 1306.6;Gastric chief cells: 7302.6;Hepatocytes: 5210.4;Parietal cells: 3210.5;Thymic myoid cells: 3033.3" "Cell type enhanced" "Detected in many" "astrocyte: 54.6;endothelial cell: 55.0;ependymal cell: 43.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 4000000 "Cluster 11: T-cells - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 19: Astrocytes - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 97: Non-specific - Cellular respiration" 2 "unprognostic (2.84e-1)" "unprognostic (1.66e-1)" "unprognostic (1.45e-1)" "unprognostic (4.51e-3)" "unprognostic (1.25e-1)" "unprognostic (1.61e-2)" "unprognostic (3.97e-2)" "unprognostic (1.69e-1)" "unprognostic (3.40e-3)" "unprognostic (2.74e-3)" "potential prognostic unfavorable (8.13e-4)" "unprognostic (2.68e-2)" "unprognostic (2.71e-2)" "unprognostic (1.54e-2)" "potential prognostic favorable (3.89e-4)" "unprognostic (7.97e-3)" "unprognostic (1.92e-2)" "unprognostic (2.79e-1)" "unprognostic (4.88e-2)" "unprognostic (9.75e-2)" "unprognostic (1.64e-1)" "unprognostic (9.30e-3)" "unprognostic (1.14e-2)" "unprognostic (2.27e-1)" "unprognostic (1.22e-2)" "unprognostic (4.95e-2)" "unprognostic (1.71e-1)" "unprognostic (3.34e-2)" "unprognostic (6.77e-2)" "unprognostic (9.27e-2)" "unprognostic (5.80e-2)" MT2A MT2 ENSG00000125148 "Metallothionein 2A" P02795 16 56608584-56609497 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 15847.5" "Cell type enhanced" "Detected in many" "Endometrial luminal cells: 7283.1;Enterocytes: 8637.3;Epididymal basal cells: 11983.6;Epididymal efferent duct absorptive cells: 7109.8;Epididymal efferent duct ciliated cells: 5989.2;Gastric chief cells: 9168.9;Hepatocytes: 19708.3;Pancreatic acinar cells: 4887.1;Pericytes: 4391.3;Thymic myoid cells: 5487.4;Vascular smooth muscle cells: 4902.3" "Cell type enhanced" "Detected in all" "astrocyte: 782.5;endothelial cell: 792.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Neutrophils" "Not detected" "Not detected" NA NA 4100000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 70: Non-specific - Protein processing" "Cluster 19: Astrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 103: Non-specific - Basic cellular processes" 24 "unprognostic (1.25e-1)" "unprognostic (2.04e-1)" "unprognostic (1.04e-1)" "unprognostic (4.85e-2)" "unprognostic (1.15e-1)" "unprognostic (1.28e-1)" "unprognostic (1.21e-1)" "unprognostic (1.86e-3)" "potential prognostic unfavorable (5.87e-4)" "unprognostic (8.57e-3)" "potential prognostic unfavorable (2.54e-5)" "unprognostic (1.58e-2)" "unprognostic (9.80e-2)" "unprognostic (1.19e-1)" "potential prognostic favorable (8.18e-4)" "unprognostic (2.34e-3)" "unprognostic (1.85e-2)" "unprognostic (1.18e-3)" "unprognostic (1.89e-2)" "unprognostic (1.00e-1)" "unprognostic (1.24e-1)" "validated prognostic unfavorable (6.39e-4)" "validated prognostic unfavorable (7.06e-4)" "unprognostic (2.92e-1)" "unprognostic (2.32e-1)" "unprognostic (7.69e-2)" "unprognostic (1.70e-1)" "unprognostic (8.10e-3)" "unprognostic (1.32e-1)" "unprognostic (1.68e-1)" "unprognostic (2.30e-1)" MT3 GIF ENSG00000087250 "Metallothionein 3" P25713 16 56589074-56591088 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "brain: 7006.0" "Cell type enhanced" "Detected in many" "Astrocytes: 462.5;Bergmann glia: 516.6;Ependymal cells: 78.8;Epididymal efferent duct absorptive cells: 92.9;Müller glia: 274.8;Oligodendrocyte progenitor cells: 209.7;Oligodendrocytes: 80.6;Schwann cells: 301.0" "Cell type enhanced" "Detected in all" "astrocyte: 447.5;Bergmann glia: 792.2" "Cancer enriched" "Detected in all" 34 "Glioblastoma Multiforme (TCGA): 4855.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "naive CD8 T-cell: 5.0" "Lineage enriched" "Detected in single" 51 "T-cells: 5.0" "Cancer enhanced" "Detected in some" "colorectal cancer: 9.5;Kidney cancer: 27.1" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Pituitary gland - Undifferentiated cells (Pituitary gland)" "Low region specificity" "Detected in all" "HPA004011, CAB017779" Enhanced NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 78: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 11: Muller glia cells - Retinal homeostasis" 7 "CAB017779: , HPA004011: " "unprognostic (1.01e-1)" "unprognostic (2.13e-2)" "unprognostic (7.24e-2)" "unprognostic (3.52e-3)" "unprognostic (3.11e-1)" "unprognostic (1.27e-2)" "unprognostic (1.50e-2)" "unprognostic (4.74e-2)" "unprognostic (8.75e-2)" "unprognostic (9.91e-2)" "unprognostic (1.12e-1)" "unprognostic (1.45e-2)" "unprognostic (7.45e-3)" "unprognostic (3.88e-2)" "unprognostic (2.58e-1)" "unprognostic (3.26e-1)" "unprognostic (3.67e-3)" "unprognostic (3.66e-1)" "unprognostic (7.52e-2)" "unprognostic (3.53e-1)" "unprognostic (2.88e-1)" "unprognostic (1.35e-1)" "unprognostic (1.69e-1)" "unprognostic (1.69e-1)" "unprognostic (5.22e-2)" "unprognostic (3.86e-1)" "unprognostic (1.68e-1)" "unprognostic (1.56e-1)" "unprognostic (2.38e-1)" MT4 MTIV ENSG00000102891 "Metallothionein 4" P47944 16 56565073-56568957 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "skin 1: 151.4" "Group enriched" "Detected in some" 8 "Basal keratinocytes: 23.9;Suprabasal keratinocytes: 18.3" "Low cell type specificity" "Detected in single" "Cancer enriched" "Detected in many" 4 "Uterine Corpus Endometrial Carcinoma (TCGA): 69.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 20 "colorectal cancer: 13.9" "Skin - Hair cortex cells, Skin - Inner root sheath cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 85: Squamous epithelial cells - Keratinization" "unprognostic (3.58e-1)" "unprognostic (3.50e-1)" "unprognostic (3.40e-1)" "unprognostic (1.54e-1)" MTA1 ENSG00000182979 "Metastasis associated 1" Q13330 14 105419820-105470729 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 242.7;Epididymal principal cells: 369.8;Esophageal apical cells: 114.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004508, HPA005544" Supported Enhanced Nucleoplasm,Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" 112 Nucleoplasm Cytosol "CAB004508: , HPA005544: " "unprognostic (3.24e-2)" "unprognostic (2.75e-3)" "unprognostic (2.32e-1)" "unprognostic (1.34e-1)" "unprognostic (3.96e-1)" "unprognostic (4.28e-2)" "unprognostic (3.16e-2)" "unprognostic (3.63e-3)" "unprognostic (4.34e-2)" "unprognostic (9.18e-2)" "unprognostic (1.18e-1)" "unprognostic (1.09e-1)" "unprognostic (1.87e-2)" "potential prognostic unfavorable (4.06e-5)" "unprognostic (4.21e-2)" "unprognostic (1.14e-1)" "unprognostic (1.32e-1)" "unprognostic (7.61e-2)" "unprognostic (1.03e-1)" "unprognostic (6.56e-2)" "unprognostic (1.11e-1)" "potential prognostic favorable (7.88e-4)" "unprognostic (5.16e-3)" "unprognostic (5.39e-3)" "unprognostic (3.35e-1)" "unprognostic (9.64e-2)" "unprognostic (2.82e-2)" "unprognostic (9.87e-2)" "unprognostic (5.17e-2)" "unprognostic (8.93e-2)" "unprognostic (3.04e-1)" MTA2 "MTA1-L1, MTA1L1" ENSG00000149480 "Metastasis associated 1 family member 2" O94776 11 62593214-62601865 "Plasma proteins, Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 51.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005315, HPA006214, CAB017522, HPA072727" Supported Enhanced Nucleoplasm NA NA 7800 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 49: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" 130 Nucleoplasm "CAB005315: , CAB017522: , HPA006214: , HPA072727: " "unprognostic (6.02e-2)" "unprognostic (1.99e-2)" "unprognostic (1.60e-1)" "unprognostic (1.80e-1)" "unprognostic (1.83e-1)" "unprognostic (1.45e-1)" "unprognostic (1.57e-1)" "unprognostic (1.42e-3)" "unprognostic (1.16e-1)" "unprognostic (9.59e-2)" "unprognostic (9.72e-3)" "unprognostic (4.88e-2)" "unprognostic (1.33e-1)" "potential prognostic unfavorable (7.45e-8)" "unprognostic (7.10e-2)" "unprognostic (1.43e-3)" "potential prognostic unfavorable (1.01e-4)" "unprognostic (1.51e-1)" "unprognostic (5.89e-2)" "unprognostic (3.37e-2)" "unprognostic (1.62e-1)" "unprognostic (1.35e-2)" "unprognostic (2.91e-1)" "unprognostic (8.65e-2)" "unprognostic (1.15e-1)" "unprognostic (2.63e-1)" "unprognostic (8.44e-2)" "unprognostic (3.81e-2)" "unprognostic (5.86e-2)" "unprognostic (7.36e-2)" "unprognostic (7.91e-2)" MTA3 KIAA1266 ENSG00000057935 "Metastasis associated 1 family member 3" Q9BTC8 2 42494569-42756947 "Plasma proteins, Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 65.6" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 346.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039433 Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 80: Thymus - Adaptive immune response" "Cluster 51: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 18: Adrenal cortex cells - Steroidogensis" 34 Nucleoplasm Vesicles "HPA039433: " "unprognostic (3.84e-2)" "unprognostic (1.14e-1)" "unprognostic (1.84e-1)" "unprognostic (1.75e-1)" "unprognostic (5.44e-1)" "unprognostic (1.36e-1)" "unprognostic (7.93e-2)" "unprognostic (5.95e-3)" "unprognostic (2.10e-1)" "unprognostic (5.19e-2)" "unprognostic (5.95e-3)" "unprognostic (1.70e-2)" "unprognostic (1.94e-1)" "validated prognostic unfavorable (3.39e-4)" "validated prognostic unfavorable (1.56e-4)" "unprognostic (3.10e-1)" "unprognostic (5.88e-2)" "unprognostic (8.13e-2)" "unprognostic (7.41e-2)" "unprognostic (1.63e-1)" "unprognostic (1.99e-1)" "unprognostic (8.55e-2)" "unprognostic (5.73e-3)" "unprognostic (5.81e-2)" "unprognostic (3.81e-1)" "unprognostic (2.02e-1)" "unprognostic (9.88e-2)" "unprognostic (3.99e-2)" "unprognostic (2.87e-1)" "unprognostic (7.55e-2)" "unprognostic (1.32e-2)" MTAP "c86fus, MSAP" ENSG00000099810 "Methylthioadenosine phosphorylase" Q13126 9 21802636-21937651 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Purine salvage" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 12.6;Early spermatids: 19.1;Late primary spermatocytes: 29.3" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046915, CAB080036, CAB080037" Approved Supported Nucleoplasm,Cytosol NA NA 1500000 "Cluster 30: Non-specific - DNA binding" "Cluster 75: Ovary - Mixed function" "Cluster 30: White matter - Myelination" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 6 Cytosol Nucleoplasm "CAB080036: , CAB080037: , HPA046915: " "unprognostic (1.86e-2)" "unprognostic (6.71e-2)" "unprognostic (1.83e-1)" "unprognostic (4.40e-2)" "unprognostic (4.62e-3)" "potential prognostic unfavorable (4.20e-4)" "unprognostic (1.68e-1)" "potential prognostic favorable (3.93e-6)" "unprognostic (3.82e-2)" "unprognostic (2.51e-2)" "potential prognostic favorable (1.22e-5)" "unprognostic (5.29e-3)" "unprognostic (4.04e-2)" "unprognostic (1.01e-3)" "unprognostic (2.56e-3)" "unprognostic (4.55e-3)" "unprognostic (2.26e-3)" "unprognostic (1.83e-1)" "unprognostic (2.26e-1)" "unprognostic (1.11e-1)" "unprognostic (1.32e-1)" "unprognostic (2.97e-2)" "unprognostic (2.53e-2)" "unprognostic (4.83e-2)" "unprognostic (4.14e-2)" "unprognostic (5.09e-3)" "unprognostic (4.12e-1)" "unprognostic (8.34e-2)" "unprognostic (2.36e-1)" "unprognostic (5.05e-2)" "unprognostic (2.37e-1)" MTARC1 "FLJ22390, MARC1, MOSC1" ENSG00000186205 "Mitochondrial amidoxime reducing component 1" Q5VT66 1 220786352-220819659 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 160.5;breast: 74.8;liver: 79.5" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 11.9;Loop of henle epithelial cells: 17.5;Monocyte progenitors: 5.9;Neutrophils: 11.2;Papillary tip epithelial cells: 7.7;Podocytes: 8.3;Proximal tubule cells: 30.5;Renal collecting duct intercalated cells: 9.8;Renal collecting duct principal cells: 17.4;Renal connecting tubule cells: 12.3;Tuft cells: 11.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 100.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "basophil: 31.2;classical monocyte: 36.5;eosinophil: 13.7;neutrophil: 46.9" "Group enriched" "Detected in many" 32 "granulocytes: 46.9;monocytes: 36.5" "Cancer enhanced" "Detected in many" "prostate cancer: 72.4" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Prostate - Prostate glandular cells, Skin - Adipocytes (Skin), Spleen - Neutrophils_2, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA028702 Approved Supported Mitochondria NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 60: Prostate cancer - Unknown function" "Cluster 105: Non-specific - Mixed function" 2 Mitochondria "HPA028702: " "unprognostic (2.17e-1)" "unprognostic (9.00e-2)" "unprognostic (6.48e-2)" "unprognostic (2.55e-1)" "unprognostic (8.09e-3)" "unprognostic (3.51e-2)" "unprognostic (7.23e-2)" "unprognostic (1.74e-1)" "unprognostic (2.15e-1)" "unprognostic (5.30e-3)" "unprognostic (2.01e-2)" "unprognostic (2.07e-2)" "unprognostic (8.03e-3)" "unprognostic (2.57e-1)" "unprognostic (6.45e-2)" "unprognostic (2.17e-1)" "unprognostic (3.48e-2)" "unprognostic (8.49e-3)" "unprognostic (2.06e-1)" "unprognostic (2.05e-1)" "unprognostic (4.28e-2)" "unprognostic (3.89e-1)" "unprognostic (6.79e-2)" "potential prognostic unfavorable (9.82e-4)" "unprognostic (1.21e-1)" "unprognostic (4.11e-1)" "unprognostic (3.37e-2)" "unprognostic (2.21e-1)" "unprognostic (3.55e-1)" MTARC2 "FLJ20605, MARC2, MOSC2" ENSG00000117791 "Mitochondrial amidoxime reducing component 2" Q969Z3 1 220748225-220784815 "Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 123.2;liver: 208.6" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 266.6;Enterocytes: 114.9;Hepatocytes: 155.3;Pituitary stem cells: 103.3;Proximal tubule cells: 227.7;Sertoli cells: 131.3" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 217.5" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "choroid plexus: 109.4" "Immune cell enriched" "Detected in some" 6 "basophil: 14.2" "Lineage enriched" "Detected in many" 6 "granulocytes: 14.2" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Minor Salivary Gland - Minor salivary gland ductal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015085, HPA017572" Enhanced NA NA "Cluster 16: Liver & Kidney - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 1 "HPA015085: , HPA017572: " "unprognostic (2.93e-2)" "unprognostic (1.66e-2)" "unprognostic (2.73e-1)" "unprognostic (7.76e-3)" "unprognostic (2.08e-1)" "unprognostic (4.81e-2)" "potential prognostic unfavorable (1.09e-5)" "unprognostic (1.07e-1)" "unprognostic (3.35e-2)" "potential prognostic favorable (5.25e-7)" "unprognostic (2.22e-3)" "unprognostic (1.18e-2)" "potential prognostic favorable (3.61e-6)" "unprognostic (2.06e-1)" "unprognostic (3.95e-3)" "unprognostic (2.20e-2)" "unprognostic (1.46e-1)" "unprognostic (1.91e-1)" "unprognostic (3.88e-1)" "unprognostic (9.62e-2)" "unprognostic (1.93e-1)" "unprognostic (2.57e-2)" "unprognostic (7.00e-2)" "unprognostic (3.64e-3)" "unprognostic (1.98e-3)" "unprognostic (1.44e-1)" "unprognostic (1.13e-1)" "unprognostic (1.44e-2)" "unprognostic (8.64e-2)" MTBP ENSG00000172167 "MDM2 binding protein" Q96DY7 8 120445400-120542133 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Growth arrest, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 66.8;Early primary spermatocytes: 112.0;Erythrocyte progenitors: 57.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA025694, HPA050594" Uncertain Approved "Nucleoplasm,Nuclear bodies" Yes No "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 2: Neurons - Nucleosome" "Cluster 40: Non-specific - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 13 Nucleoplasm "Nuclear bodies" "HPA025694: , HPA050594: " "unprognostic (1.01e-1)" "unprognostic (3.97e-2)" "unprognostic (4.96e-2)" "unprognostic (1.94e-1)" "unprognostic (1.94e-2)" "unprognostic (8.95e-2)" "unprognostic (1.91e-1)" "unprognostic (1.91e-2)" "unprognostic (1.29e-3)" "unprognostic (7.34e-2)" "unprognostic (2.93e-2)" "potential prognostic unfavorable (4.03e-5)" "unprognostic (1.24e-3)" "potential prognostic unfavorable (3.66e-5)" "unprognostic (1.07e-2)" "unprognostic (2.62e-2)" "unprognostic (9.17e-3)" "unprognostic (2.20e-2)" "unprognostic (1.66e-1)" "unprognostic (4.33e-3)" "potential prognostic unfavorable (7.60e-5)" "unprognostic (8.19e-2)" "unprognostic (1.23e-2)" "unprognostic (6.29e-3)" "unprognostic (3.91e-2)" "unprognostic (1.16e-2)" "unprognostic (3.57e-1)" "unprognostic (6.08e-2)" MTCH1 "CGI-64, PSAP, SLC25A49" ENSG00000137409 "Mitochondrial carrier 1" Q9NZJ7 6 36965807-36986298 "Predicted membrane proteins, Transporters" "Apoptosis, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epididymal principal cells: 800.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Pituitary gland - Corticotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015971 Approved NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 20 "HPA015971: " "unprognostic (1.77e-1)" "unprognostic (2.06e-2)" "unprognostic (7.03e-2)" "unprognostic (4.03e-1)" "unprognostic (1.14e-1)" "unprognostic (1.51e-2)" "unprognostic (6.23e-2)" "unprognostic (3.57e-3)" "unprognostic (2.63e-1)" "unprognostic (1.44e-2)" "validated prognostic favorable (2.32e-7)" "validated prognostic favorable (2.38e-4)" "unprognostic (5.97e-2)" "validated prognostic unfavorable (1.00e-5)" "validated prognostic unfavorable (2.76e-5)" "unprognostic (4.11e-1)" "unprognostic (1.98e-3)" "unprognostic (2.51e-1)" "unprognostic (8.33e-2)" "unprognostic (2.31e-1)" "unprognostic (4.74e-1)" "unprognostic (1.87e-1)" "unprognostic (3.17e-1)" "unprognostic (9.76e-3)" "unprognostic (7.27e-3)" "unprognostic (1.11e-2)" "unprognostic (4.14e-2)" "unprognostic (4.44e-2)" "unprognostic (3.77e-1)" "unprognostic (3.07e-2)" "unprognostic (9.13e-2)" MTCH2 SLC25A50 ENSG00000109919 "Mitochondrial carrier 2" Q9Y6C9 11 47617315-47642607 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 205.2;Early spermatids: 505.1;Gastric progenitor cells: 293.5;Hepatocytes: 201.1;Late primary spermatocytes: 725.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038390 Approved Approved Mitochondria NA NA 100000 "Cluster 13: Non-specific - Mitochondria" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 21: Non-specific - Metabolism" "Cluster 24: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 81 Mitochondria "HPA038390: " "unprognostic (1.78e-2)" "unprognostic (9.83e-3)" "unprognostic (8.03e-2)" "unprognostic (1.14e-1)" "unprognostic (3.51e-2)" "unprognostic (1.05e-2)" "unprognostic (2.92e-1)" "unprognostic (9.16e-2)" "unprognostic (5.16e-2)" "unprognostic (4.93e-3)" "potential prognostic favorable (1.65e-8)" "unprognostic (1.22e-1)" "unprognostic (2.42e-2)" "unprognostic (4.84e-2)" "unprognostic (1.16e-2)" "unprognostic (3.16e-2)" "unprognostic (1.15e-2)" "unprognostic (1.31e-1)" "unprognostic (2.63e-1)" "unprognostic (7.05e-2)" "unprognostic (1.04e-1)" "unprognostic (9.03e-2)" "unprognostic (1.09e-1)" "unprognostic (1.97e-1)" "unprognostic (1.75e-2)" "unprognostic (2.49e-1)" "unprognostic (2.34e-1)" "unprognostic (7.84e-3)" "unprognostic (2.15e-1)" "unprognostic (3.52e-1)" "unprognostic (2.20e-1)" MTCL1 "CCDC165, KIAA0802, SOGA2" ENSG00000168502 "Microtubule crosslinking factor 1" Q9Y4B5 18 8705556-8832778 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 31.0;retina: 14.4" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 240.1;Cone photoreceptor cells: 252.6;Corticotrophs: 275.4;Lactotrophs: 189.8;Müller glia: 390.0;Retinal bipolar cells: 299.3;Rod photoreceptor cells: 397.9;Sertoli cells: 216.6;Thyrotrophs: 259.7" "Cell type enhanced" "Detected in all" "upper rhombic lip: 722.9" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 5 "cerebellum: 176.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 92.3" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Adrenal medulla cells, Prostate - Smooth muscle cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 44.1" HPA046245 Uncertain NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 35: Non-specific - DNA binding" "Cluster 6: Leukemia - Signal transduction" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 19 "HPA046245: " "unprognostic (9.14e-2)" "unprognostic (2.45e-1)" "unprognostic (1.62e-2)" "unprognostic (2.35e-1)" "unprognostic (2.86e-2)" "unprognostic (2.79e-1)" "unprognostic (7.73e-3)" "unprognostic (2.38e-1)" "unprognostic (3.50e-2)" "unprognostic (3.71e-3)" "unprognostic (9.70e-2)" "potential prognostic unfavorable (1.13e-4)" "potential prognostic unfavorable (6.34e-5)" "unprognostic (4.05e-1)" "unprognostic (1.24e-2)" "unprognostic (3.05e-3)" "unprognostic (7.81e-2)" "unprognostic (4.42e-2)" "unprognostic (4.63e-2)" "unprognostic (3.92e-3)" "unprognostic (6.34e-3)" "unprognostic (1.27e-1)" "unprognostic (8.30e-2)" "unprognostic (6.01e-2)" "unprognostic (2.15e-1)" "unprognostic (2.64e-1)" "unprognostic (1.94e-1)" MTCP1 "P13MTCP1, p8MTCP1, TCL1C" ENSG00000214827 "Mature T cell proliferation 1" P56278 X 155064034-155147937 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 5 "Sertoli cells: 769.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 6.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA032040 Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 56: Non-specific - Sensory perception" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 1 Nucleoplasm "Plasma membrane" "HPA032040: " "unprognostic (6.51e-2)" "unprognostic (3.59e-1)" "unprognostic (5.84e-2)" "unprognostic (1.21e-1)" "unprognostic (2.14e-1)" "unprognostic (9.91e-2)" "unprognostic (6.69e-2)" "unprognostic (1.59e-1)" "potential prognostic unfavorable (9.43e-4)" "unprognostic (3.13e-1)" "unprognostic (3.98e-2)" "unprognostic (6.54e-2)" "unprognostic (2.96e-1)" "unprognostic (3.25e-2)" "unprognostic (1.12e-1)" "unprognostic (1.95e-1)" "unprognostic (1.24e-1)" "unprognostic (2.71e-2)" "unprognostic (2.35e-2)" "unprognostic (2.13e-3)" "unprognostic (1.45e-1)" "unprognostic (1.46e-2)" "unprognostic (2.69e-2)" MTDH "3D3, AEG-1, LYRIC" ENSG00000147649 Metadherin Q86UE4 8 97644184-97730260 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "HPA010932, HPA015104, CAB068204, CAB068205" Supported Enhanced "Endoplasmic reticulum" NA NA 80000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 44: Plasma cells - Antibody production & secretion" 64 "Endoplasmic reticulum" "CAB068204: , CAB068205: , HPA010932: , HPA015104: " "unprognostic (1.43e-1)" "potential prognostic unfavorable (5.34e-4)" "unprognostic (1.14e-2)" "unprognostic (5.29e-3)" "unprognostic (4.73e-2)" "unprognostic (7.13e-3)" "unprognostic (3.56e-1)" "unprognostic (3.88e-2)" "unprognostic (7.58e-2)" "potential prognostic unfavorable (1.83e-4)" "potential prognostic favorable (4.51e-5)" "unprognostic (1.19e-1)" "unprognostic (1.03e-2)" "unprognostic (6.46e-2)" "potential prognostic unfavorable (9.24e-4)" "unprognostic (8.77e-3)" "unprognostic (2.19e-3)" "unprognostic (1.10e-2)" "unprognostic (1.40e-1)" "unprognostic (2.83e-2)" "potential prognostic unfavorable (2.68e-5)" "unprognostic (1.62e-3)" "unprognostic (3.36e-3)" "unprognostic (2.63e-2)" "unprognostic (6.35e-2)" "unprognostic (1.43e-1)" "unprognostic (1.02e-1)" "unprognostic (2.15e-2)" "unprognostic (2.19e-1)" "unprognostic (6.69e-2)" "unprognostic (7.17e-2)" MTERF1 MTERF ENSG00000127989 "Mitochondrial transcription termination factor 1" Q99551 7 91692008-91880702 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Transcription termination" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 158.0;Oligodendrocytes: 174.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044894, HPA069560" Uncertain Supported Mitochondria NA NA "Cluster 32: Basophils - Transcription" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 30: White matter - Myelination" "Cluster 39: Non-specific - Transcription" "Cluster 80: Oligodendrocytes - Myelination" 2 Mitochondria "HPA044894: , HPA069560: " "unprognostic (1.13e-1)" "unprognostic (2.04e-1)" "unprognostic (4.15e-2)" "unprognostic (1.15e-2)" "potential prognostic favorable (9.40e-4)" "unprognostic (1.16e-1)" "unprognostic (2.30e-1)" "unprognostic (4.60e-1)" "potential prognostic unfavorable (8.80e-4)" "potential prognostic favorable (1.14e-6)" "unprognostic (1.07e-1)" "unprognostic (1.80e-1)" "unprognostic (3.54e-3)" "unprognostic (2.40e-2)" "unprognostic (3.96e-3)" "unprognostic (9.53e-3)" "unprognostic (7.89e-3)" "unprognostic (8.26e-2)" "unprognostic (6.71e-2)" "unprognostic (2.46e-1)" "potential prognostic unfavorable (3.72e-4)" "unprognostic (9.50e-3)" "unprognostic (6.18e-2)" "unprognostic (2.80e-2)" "unprognostic (4.68e-2)" "unprognostic (2.25e-1)" "unprognostic (4.07e-2)" "unprognostic (9.98e-2)" "unprognostic (8.10e-2)" MTERF2 "FLJ14062, MTERFD3" ENSG00000120832 "Mitochondrial transcription termination factor 2" Q49AM1 12 106977277-106987160 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003526 Approved NA NA "Cluster 11: T-cells - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 16: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 4 "HPA003526: " "unprognostic (4.01e-2)" "unprognostic (7.96e-2)" "unprognostic (2.31e-1)" "unprognostic (2.63e-2)" "unprognostic (1.24e-1)" "unprognostic (2.36e-1)" "unprognostic (2.69e-2)" "unprognostic (2.19e-1)" "unprognostic (1.46e-1)" "unprognostic (2.80e-1)" "unprognostic (3.62e-3)" "unprognostic (4.79e-3)" "unprognostic (2.96e-2)" "unprognostic (7.20e-3)" "unprognostic (1.48e-1)" "unprognostic (1.38e-2)" "potential prognostic favorable (5.88e-5)" "unprognostic (2.10e-1)" "unprognostic (1.34e-1)" "potential prognostic favorable (1.04e-4)" "unprognostic (5.92e-2)" "unprognostic (1.70e-2)" "unprognostic (1.03e-2)" "unprognostic (8.02e-2)" "unprognostic (1.34e-2)" "unprognostic (2.80e-1)" "unprognostic (6.94e-3)" "unprognostic (7.56e-2)" "unprognostic (1.93e-2)" MTERF3 "CGI-12, FLJ10939, MTERFD1" ENSG00000156469 "Mitochondrial transcription termination factor 3" Q96E29 8 96239398-96261610 "Predicted intracellular proteins" "Ribosome biogenesis, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 119.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007355 Supported Mitochondria,Cytosol NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 31: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 45 Mitochondria Cytosol "HPA007355: " "unprognostic (2.00e-2)" "unprognostic (3.41e-2)" "unprognostic (9.20e-2)" "unprognostic (4.37e-1)" "unprognostic (7.56e-2)" "unprognostic (5.07e-2)" "unprognostic (1.17e-1)" "unprognostic (7.80e-2)" "unprognostic (1.77e-3)" "unprognostic (9.11e-3)" "unprognostic (9.18e-2)" "unprognostic (1.30e-2)" "unprognostic (3.14e-3)" "unprognostic (9.53e-3)" "unprognostic (4.05e-3)" "unprognostic (1.29e-1)" "unprognostic (7.36e-3)" "unprognostic (7.07e-2)" "unprognostic (3.43e-1)" "unprognostic (1.54e-1)" "potential prognostic unfavorable (8.89e-4)" "unprognostic (6.94e-2)" "unprognostic (9.40e-2)" "unprognostic (2.39e-1)" "unprognostic (9.94e-3)" "unprognostic (3.79e-2)" "unprognostic (3.80e-1)" "unprognostic (1.31e-1)" "unprognostic (5.93e-3)" MTERF4 "MGC61716, MTERFD2" ENSG00000122085 "Mitochondrial transcription termination factor 4" Q7Z6M4 2 241072169-241102332 "Predicted intracellular proteins" "rRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 296.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027097 Uncertain Supported Mitochondria,Cytosol Yes No "Cluster 43: Non-specific - Transcription & Translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 7 "Mitochondria, Cytosol" "HPA027097: " "unprognostic (9.18e-3)" "unprognostic (5.48e-2)" "unprognostic (9.37e-3)" "unprognostic (2.35e-2)" "unprognostic (1.57e-1)" "unprognostic (1.22e-2)" "unprognostic (1.74e-1)" "unprognostic (4.08e-2)" "unprognostic (8.82e-2)" "validated prognostic favorable (8.61e-7)" "validated prognostic favorable (2.41e-4)" "unprognostic (1.86e-1)" "potential prognostic unfavorable (5.98e-4)" "unprognostic (1.57e-1)" "unprognostic (3.69e-1)" "unprognostic (5.41e-2)" "unprognostic (5.68e-2)" "unprognostic (1.76e-3)" "unprognostic (1.75e-1)" "unprognostic (3.17e-2)" "unprognostic (4.15e-2)" "unprognostic (7.31e-2)" "unprognostic (8.65e-2)" "unprognostic (3.56e-1)" "unprognostic (1.01e-2)" "unprognostic (1.10e-1)" "unprognostic (1.48e-1)" "unprognostic (1.25e-1)" "unprognostic (1.73e-1)" MTF1 ENSG00000188786 "Metal regulatory transcription factor 1" Q14872 1 37809574-37859592 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 19.4" "Group enriched" "Detected in many" 4 "Neutrophil progenitors: 235.7;Neutrophils: 795.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028604, HPA028689" Uncertain Enhanced Nucleoplasm NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 3 Nucleoplasm "HPA028604: , HPA028689: " "unprognostic (6.31e-3)" "unprognostic (1.52e-1)" "unprognostic (1.85e-1)" "unprognostic (1.32e-2)" "unprognostic (6.32e-2)" "unprognostic (1.34e-1)" "unprognostic (2.90e-2)" "unprognostic (1.25e-1)" "unprognostic (8.94e-3)" "unprognostic (2.04e-2)" "potential prognostic favorable (2.64e-5)" "unprognostic (1.06e-3)" "unprognostic (1.79e-1)" "potential prognostic unfavorable (1.59e-4)" "unprognostic (2.10e-2)" "unprognostic (1.47e-1)" "unprognostic (1.28e-1)" "unprognostic (2.38e-1)" "unprognostic (1.40e-1)" "unprognostic (5.95e-2)" "unprognostic (4.78e-3)" "unprognostic (8.88e-2)" "unprognostic (1.90e-2)" "unprognostic (2.60e-2)" "unprognostic (6.04e-3)" "unprognostic (2.10e-3)" "unprognostic (1.60e-1)" "unprognostic (2.91e-2)" "unprognostic (1.84e-1)" "unprognostic (3.37e-2)" "unprognostic (6.61e-2)" MTF2 "M96, PCL2, TDRD19A" ENSG00000143033 "Metal response element binding transcription factor 2" Q9Y483 1 93079235-93139079 "Predicted intracellular proteins" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Sertoli cells: 284.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069047, HPA069066" Supported Nucleoplasm NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 31: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 15 Nucleoplasm "HPA069047: , HPA069066: " "unprognostic (1.40e-1)" "unprognostic (2.61e-1)" "potential prognostic favorable (7.66e-5)" "unprognostic (2.37e-1)" "unprognostic (1.15e-3)" "unprognostic (6.58e-2)" "unprognostic (9.20e-2)" "unprognostic (1.51e-3)" "unprognostic (4.40e-2)" "unprognostic (3.55e-2)" "unprognostic (2.94e-1)" "unprognostic (6.28e-2)" "unprognostic (1.17e-1)" "potential prognostic unfavorable (8.89e-8)" "unprognostic (5.87e-2)" "unprognostic (8.21e-2)" "unprognostic (3.92e-2)" "unprognostic (7.73e-2)" "unprognostic (4.17e-3)" "unprognostic (1.33e-1)" "unprognostic (9.64e-2)" "unprognostic (2.72e-2)" "unprognostic (6.56e-3)" "unprognostic (3.94e-2)" "unprognostic (6.28e-2)" "unprognostic (2.33e-2)" "unprognostic (5.86e-2)" "unprognostic (1.40e-2)" "unprognostic (1.04e-1)" "unprognostic (2.23e-1)" "unprognostic (2.97e-2)" MTFMT FMT1 ENSG00000103707 "Mitochondrial methionyl-tRNA formyltransferase" Q96DP5 15 65001512-65029639 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" Transferase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Myonuclei: 101.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040710 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 70: Non-specific - Protein processing" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 58: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" 1 Nucleoplasm Cytosol "HPA040710: " "unprognostic (2.47e-1)" "unprognostic (4.61e-2)" "unprognostic (1.68e-2)" "unprognostic (7.74e-2)" "unprognostic (6.09e-2)" "unprognostic (4.32e-2)" "unprognostic (3.68e-2)" "unprognostic (1.19e-2)" "unprognostic (3.11e-1)" "potential prognostic unfavorable (9.64e-5)" "unprognostic (3.01e-2)" "potential prognostic favorable (2.42e-5)" "potential prognostic favorable (5.79e-4)" "unprognostic (8.69e-2)" "unprognostic (5.42e-2)" "unprognostic (9.42e-2)" "unprognostic (1.84e-1)" "unprognostic (1.61e-1)" "unprognostic (1.13e-1)" "unprognostic (1.58e-1)" "unprognostic (1.87e-1)" "unprognostic (3.23e-2)" "unprognostic (1.36e-1)" "unprognostic (2.17e-1)" "unprognostic (3.93e-2)" "unprognostic (1.70e-3)" "potential prognostic unfavorable (1.17e-4)" "unprognostic (1.26e-1)" "unprognostic (3.14e-2)" "unprognostic (7.61e-2)" "unprognostic (4.31e-2)" MTFP1 "HSPC242, MTP18" ENSG00000242114 "Mitochondrial fission process 1" Q9UDX5 22 30425623-30429054 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 33.2;Enteric stem cells: 39.5;Enteric transient amplifying cells: 49.0;Epididymal efferent duct absorptive cells: 35.7;Epididymal principal cells: 50.1;Extravillous trophoblasts: 35.7;Müller glia: 29.6;Parietal cells: 72.5" "Cell type enhanced" "Detected in many" "leukocyte: 12.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077396 Approved Mitochondria NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 15: Non-specific - Protein processing" 2 Mitochondria "HPA077396: " "unprognostic (1.38e-2)" "unprognostic (5.62e-2)" "unprognostic (7.09e-2)" "unprognostic (1.02e-1)" "unprognostic (3.72e-1)" "unprognostic (3.08e-2)" "unprognostic (1.69e-2)" "unprognostic (3.01e-3)" "unprognostic (1.54e-2)" "unprognostic (3.56e-3)" "unprognostic (5.44e-3)" "unprognostic (1.24e-2)" "validated prognostic unfavorable (4.23e-4)" "validated prognostic unfavorable (1.01e-5)" "unprognostic (3.23e-3)" "unprognostic (5.84e-2)" "potential prognostic favorable (9.84e-4)" "unprognostic (1.37e-2)" "unprognostic (1.94e-1)" "unprognostic (9.65e-2)" "unprognostic (3.68e-3)" "unprognostic (5.18e-2)" "unprognostic (2.50e-1)" "unprognostic (2.70e-2)" "unprognostic (7.79e-2)" "unprognostic (2.73e-1)" "unprognostic (6.09e-2)" "unprognostic (5.51e-2)" "unprognostic (3.21e-1)" "unprognostic (4.47e-2)" MTFR1 "CHPPR, FAM54A2, KIAA0009" ENSG00000066855 "Mitochondrial fission regulator 1" Q15390 8 65644734-65771261 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Cardiomyocytes: 3739.9;Late spermatids: 1346.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023152, HPA056120" Uncertain Supported Mitochondria,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 76: Non-specific - Metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 40: Non-specific - Unknown function" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 15 Mitochondria Cytosol "HPA023152: , HPA056120: " "unprognostic (3.43e-1)" "potential prognostic unfavorable (1.13e-4)" "unprognostic (6.25e-2)" "unprognostic (2.55e-2)" "unprognostic (2.02e-1)" "unprognostic (9.55e-2)" "unprognostic (1.72e-2)" "unprognostic (1.25e-1)" "unprognostic (3.90e-2)" "unprognostic (2.01e-2)" "potential prognostic favorable (1.27e-7)" "unprognostic (1.08e-1)" "unprognostic (6.98e-2)" "unprognostic (1.38e-1)" "unprognostic (8.10e-2)" "potential prognostic unfavorable (9.63e-4)" "unprognostic (2.27e-1)" "unprognostic (4.60e-2)" "unprognostic (2.89e-1)" "unprognostic (1.31e-1)" "unprognostic (2.38e-2)" "unprognostic (2.12e-3)" "unprognostic (1.15e-2)" "unprognostic (2.86e-2)" "unprognostic (8.90e-3)" "unprognostic (1.22e-1)" "unprognostic (2.55e-1)" "unprognostic (1.44e-1)" "unprognostic (1.86e-1)" "potential prognostic unfavorable (2.38e-4)" "unprognostic (9.11e-2)" MTFR1L FAM54B ENSG00000117640 "Mitochondrial fission regulator 1 like" Q9H019 1 25818640-25832942 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 206.2;Late primary spermatocytes: 333.8;Late spermatids: 968.7;Platelets: 290.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027124, HPA027130" Approved Approved "Cell Junctions,Mitochondria" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 37: Non-specific - mRNA processing" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 9 Mitochondria "Cell Junctions" "HPA027124: , HPA027130: " "unprognostic (2.49e-2)" "unprognostic (1.83e-1)" "unprognostic (2.95e-1)" "unprognostic (2.11e-2)" "unprognostic (1.81e-1)" "unprognostic (1.21e-1)" "unprognostic (1.23e-3)" "unprognostic (1.78e-1)" "unprognostic (6.09e-2)" "validated prognostic favorable (1.00e-8)" "validated prognostic favorable (4.94e-4)" "potential prognostic favorable (1.31e-12)" "unprognostic (9.58e-2)" "unprognostic (6.90e-3)" "unprognostic (2.97e-2)" "unprognostic (1.71e-1)" "unprognostic (3.55e-2)" "unprognostic (1.50e-1)" "unprognostic (6.66e-2)" "unprognostic (3.44e-2)" "unprognostic (2.02e-1)" "unprognostic (2.71e-2)" "unprognostic (1.13e-2)" "unprognostic (1.48e-1)" "unprognostic (3.32e-1)" "unprognostic (1.82e-1)" "unprognostic (4.41e-2)" "unprognostic (1.36e-1)" "unprognostic (1.32e-2)" MTFR2 "DUFD1, FAM54A" ENSG00000146410 "Mitochondrial fission regulator 2" Q6P444 6 136231024-136250335 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 15.4;lymphoid tissue: 6.0;testis: 6.6" "Cell type enriched" "Detected in many" 5 "Oocytes: 175.0" "Cell type enhanced" "Detected in some" "Bergmann glia: 2.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA029792, HPA029794" Approved Uncertain Vesicles NA Yes "Cluster 13: Non-specific - Mitochondria" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 28: Non-specific - Nuclear processes" "Cluster 41: Oocytes - Oogenesis" 10 Vesicles "HPA029792: , HPA029794: " "unprognostic (2.73e-3)" "unprognostic (6.32e-3)" "unprognostic (2.76e-3)" "unprognostic (4.68e-1)" "unprognostic (1.61e-1)" "unprognostic (4.61e-1)" "unprognostic (1.06e-1)" "unprognostic (3.16e-2)" "potential prognostic unfavorable (2.84e-5)" "unprognostic (4.48e-3)" "potential prognostic unfavorable (7.44e-7)" "potential prognostic unfavorable (1.03e-6)" "validated prognostic unfavorable (4.34e-5)" "validated prognostic unfavorable (3.34e-4)" "unprognostic (2.49e-2)" "unprognostic (6.98e-2)" "unprognostic (3.26e-2)" "unprognostic (3.67e-2)" "unprognostic (5.24e-2)" "unprognostic (1.80e-3)" "unprognostic (1.62e-1)" "unprognostic (1.65e-2)" "unprognostic (5.08e-2)" "unprognostic (2.77e-2)" "unprognostic (3.72e-1)" "unprognostic (1.37e-1)" MTG1 GTPBP7 ENSG00000148824 "Mitochondrial ribosome associated GTPase 1" Q9BT17 10 133394094-133422520 "Predicted intracellular proteins" "Translation regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 81.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037826, HPA037827" Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 70: Non-specific - Protein processing" "Cluster 44: Non-specific - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 5 Mitochondria "HPA037826: , HPA037827: " "potential prognostic unfavorable (8.10e-4)" "unprognostic (1.16e-1)" "unprognostic (1.45e-1)" "unprognostic (1.27e-1)" "unprognostic (1.38e-1)" "unprognostic (6.48e-2)" "unprognostic (4.86e-2)" "potential prognostic favorable (3.65e-5)" "unprognostic (3.70e-2)" "unprognostic (1.15e-1)" "unprognostic (9.39e-3)" "unprognostic (3.78e-1)" "unprognostic (1.01e-2)" "unprognostic (4.60e-2)" "unprognostic (2.34e-1)" "unprognostic (1.78e-2)" "unprognostic (1.34e-1)" "unprognostic (2.82e-2)" "unprognostic (2.38e-1)" "unprognostic (2.69e-1)" "unprognostic (3.03e-1)" "unprognostic (2.26e-2)" "unprognostic (2.99e-2)" "unprognostic (1.26e-1)" "unprognostic (1.52e-1)" "unprognostic (6.85e-2)" "unprognostic (8.03e-2)" "unprognostic (8.07e-2)" "unprognostic (1.41e-1)" "unprognostic (1.10e-1)" "unprognostic (1.33e-2)" MTG2 "dJ1005F21.2, FLJ10741, GTPBP5, ObgH1" ENSG00000101181 "Mitochondrial ribosome associated GTPase 2" Q9H4K7 20 62183028-62203568 "Predicted intracellular proteins" "Ribosome biogenesis, Translation regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047379 Approved NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 24: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 48 "HPA047379: " "unprognostic (3.25e-2)" "unprognostic (3.56e-2)" "unprognostic (3.14e-3)" "unprognostic (2.56e-1)" "unprognostic (6.65e-2)" "unprognostic (1.59e-1)" "unprognostic (7.73e-3)" "unprognostic (7.55e-2)" "unprognostic (4.06e-2)" "unprognostic (1.64e-1)" "unprognostic (1.67e-2)" "unprognostic (6.18e-2)" "unprognostic (9.64e-2)" "unprognostic (9.21e-2)" "unprognostic (1.10e-1)" "unprognostic (1.15e-1)" "unprognostic (1.35e-1)" "unprognostic (2.73e-2)" "unprognostic (1.50e-1)" "unprognostic (1.09e-2)" "unprognostic (1.33e-2)" "potential prognostic unfavorable (4.86e-4)" "unprognostic (1.31e-2)" "unprognostic (2.17e-2)" "unprognostic (3.06e-1)" "unprognostic (2.78e-1)" "unprognostic (1.37e-1)" "unprognostic (4.54e-1)" "unprognostic (3.03e-2)" MTHFD1 "MTHFC, MTHFD" ENSG00000100714 "Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1" P11586 14 64388031-64463457 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "One-carbon metabolism" "Hydrolase, Ligase, Multifunctional enzyme, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "liver: 318.5" "Cell type enhanced" "Detected in many" "Adipocytes: 125.2;Cardiomyocytes: 151.7;Epicardial cells: 102.3;Erythrocyte progenitors: 114.1;Hepatocytes: 198.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Liver - Hepatocytes, Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000704, HPA001290, HPA015006, HPA050052" Approved Enhanced Cytosol NA Yes 1600000 "Cluster 14: Non-specific - Unknown function" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 23: Choroid plexus - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 89: Adipocytes - Lipid metabolism" 20 Cytosol "HPA000704: , HPA001290: , HPA015006: , HPA050052: " "unprognostic (9.00e-3)" "unprognostic (1.87e-1)" "unprognostic (1.17e-1)" "unprognostic (1.95e-1)" "unprognostic (2.35e-2)" "unprognostic (2.80e-1)" "unprognostic (2.67e-2)" "unprognostic (9.73e-2)" "unprognostic (1.25e-1)" "unprognostic (1.08e-1)" "potential prognostic favorable (1.21e-8)" "unprognostic (2.65e-3)" "unprognostic (9.80e-2)" "unprognostic (1.63e-2)" "potential prognostic favorable (3.52e-4)" "potential prognostic unfavorable (1.82e-4)" "unprognostic (1.67e-2)" "unprognostic (5.63e-2)" "unprognostic (1.18e-1)" "unprognostic (4.58e-1)" "unprognostic (4.44e-2)" "potential prognostic unfavorable (8.88e-4)" "unprognostic (2.52e-1)" "unprognostic (1.12e-1)" "unprognostic (1.04e-1)" "unprognostic (1.32e-1)" "unprognostic (4.68e-1)" "unprognostic (1.10e-2)" "unprognostic (2.19e-1)" "unprognostic (2.32e-1)" "unprognostic (1.05e-1)" MTHFD1L "DKFZP586G1517, FLJ21145, FTHFSDC1" ENSG00000120254 "Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like" Q6UB35 6 150865679-151101887 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "One-carbon metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 60.3" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 585.8;Epicardial cells: 343.4;Extravillous trophoblasts: 405.1;Melanocytes: 766.7;Microglia: 648.4;Sertoli cells: 434.0" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 838.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015006, HPA029040, HPA029041, HPA050052, HPA074911" Approved Enhanced Mitochondria NA NA 43000 "Cluster 13: Non-specific - Mitochondria" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 25: Non-specific - Transcription" "Cluster 13: Non-specific - Mixed function" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 14 Mitochondria "HPA015006: , HPA029040: , HPA029041: , HPA050052: , HPA074911: " "potential prognostic unfavorable (2.95e-4)" "unprognostic (4.77e-2)" "unprognostic (2.40e-1)" "potential prognostic unfavorable (1.92e-4)" "unprognostic (1.75e-1)" "unprognostic (1.75e-1)" "unprognostic (2.43e-1)" "unprognostic (4.12e-2)" "unprognostic (6.30e-3)" "unprognostic (3.22e-2)" "unprognostic (3.87e-2)" "unprognostic (2.17e-1)" "unprognostic (4.14e-3)" "potential prognostic unfavorable (2.15e-6)" "unprognostic (1.02e-3)" "validated prognostic unfavorable (3.58e-4)" "validated prognostic unfavorable (9.33e-4)" "unprognostic (2.95e-2)" "unprognostic (6.24e-2)" "unprognostic (1.61e-1)" "unprognostic (2.34e-1)" "unprognostic (2.15e-2)" "potential prognostic unfavorable (1.56e-4)" "unprognostic (6.34e-2)" "unprognostic (2.58e-2)" "potential prognostic favorable (3.80e-4)" "unprognostic (6.83e-2)" "unprognostic (1.75e-1)" "unprognostic (2.79e-1)" "unprognostic (1.70e-1)" "unprognostic (4.80e-2)" MTHFD2 ENSG00000065911 "Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase" P13995 2 74186172-74217565 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "One-carbon metabolism" "Hydrolase, Multifunctional enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 151.7;Pancreatic acinar cells: 178.0;Plasma cells: 153.3;Vascular smooth muscle cells: 227.3" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 47.7;vascular associated smooth muscle cell: 35.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003684, HPA049657" Approved Supported Mitochondria NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 13: Non-specific - Mixed function" "Cluster 103: Non-specific - Basic cellular processes" 9 Mitochondria "CAB003684: , HPA049657: " "unprognostic (6.29e-2)" "unprognostic (7.97e-3)" "unprognostic (2.54e-2)" "unprognostic (9.84e-3)" "unprognostic (1.88e-1)" "unprognostic (7.83e-3)" "unprognostic (2.42e-3)" "unprognostic (3.31e-3)" "potential prognostic unfavorable (4.20e-5)" "potential prognostic unfavorable (9.55e-4)" "potential prognostic unfavorable (4.85e-7)" "unprognostic (1.51e-1)" "potential prognostic unfavorable (1.16e-10)" "unprognostic (3.67e-3)" "unprognostic (6.88e-2)" "potential prognostic unfavorable (6.02e-4)" "unprognostic (5.62e-2)" "unprognostic (2.23e-2)" "unprognostic (1.62e-1)" "unprognostic (2.07e-1)" "unprognostic (8.85e-2)" "potential prognostic unfavorable (6.92e-4)" "unprognostic (4.35e-2)" "unprognostic (1.54e-3)" "unprognostic (1.62e-1)" "unprognostic (1.25e-1)" "unprognostic (1.11e-2)" "unprognostic (3.05e-2)" "unprognostic (1.99e-1)" "unprognostic (1.24e-1)" "unprognostic (1.19e-1)" MTHFD2L MGC72244 ENSG00000163738 "Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like" Q9H903 4 74114174-74303099 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Amino-acid biosynthesis, Histidine biosynthesis, Methionine biosynthesis, One-carbon metabolism, Purine biosynthesis" "Hydrolase, Multifunctional enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "liver: 3.5" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 299.6;Breast lactating cells: 634.8;Epididymal principal cells: 295.4;Hepatocytes: 247.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035434 Uncertain NA NA "Cluster 76: Non-specific - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 4: Breast lactating luminal cells - Lactation" 1 "HPA035434: " "unprognostic (7.87e-2)" "unprognostic (2.57e-2)" "unprognostic (2.37e-1)" "unprognostic (8.44e-2)" "unprognostic (2.48e-1)" "unprognostic (1.22e-1)" "unprognostic (3.91e-2)" "unprognostic (2.43e-2)" "unprognostic (2.46e-1)" "unprognostic (4.96e-2)" "potential prognostic favorable (1.89e-5)" "unprognostic (7.74e-3)" "unprognostic (1.74e-1)" "unprognostic (1.77e-1)" "unprognostic (6.42e-2)" "unprognostic (2.49e-3)" "unprognostic (4.06e-2)" "unprognostic (2.31e-1)" "unprognostic (2.61e-1)" "unprognostic (4.40e-2)" "unprognostic (2.39e-1)" "unprognostic (4.19e-3)" "unprognostic (1.76e-1)" "unprognostic (2.55e-1)" "unprognostic (1.53e-1)" "unprognostic (1.37e-1)" "unprognostic (5.77e-2)" "unprognostic (3.23e-2)" "unprognostic (2.79e-1)" MTHFR ENSG00000177000 "Methylenetetrahydrofolate reductase" P42898 1 11785723-11806455 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Allosteric enzyme, Oxidoreductase" "Disease variant, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 152.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063389, HPA076180, HPA077255" Enhanced Approved "Cell Junctions,Centrosome,Basal body" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 103: Non-specific - Basic cellular processes" 3 "Cell Junctions" "Centrosome, Basal body" "HPA063389: , HPA076180: , HPA077255: " "unprognostic (1.92e-3)" "unprognostic (1.78e-1)" "unprognostic (3.16e-2)" "unprognostic (6.24e-3)" "unprognostic (1.36e-2)" "unprognostic (9.52e-3)" "unprognostic (1.78e-1)" "unprognostic (1.41e-3)" "unprognostic (5.98e-3)" "unprognostic (3.58e-3)" "validated prognostic favorable (2.31e-6)" "validated prognostic favorable (7.09e-6)" "unprognostic (1.58e-3)" "unprognostic (1.43e-3)" "unprognostic (6.36e-2)" "unprognostic (2.15e-2)" "unprognostic (2.22e-2)" "unprognostic (1.93e-2)" "unprognostic (2.44e-2)" "unprognostic (1.55e-1)" "unprognostic (2.72e-1)" "unprognostic (2.25e-3)" "unprognostic (3.34e-2)" "unprognostic (3.80e-1)" "unprognostic (1.84e-1)" "unprognostic (1.66e-2)" "unprognostic (3.65e-1)" "unprognostic (4.11e-2)" "unprognostic (1.25e-2)" "unprognostic (2.76e-2)" "unprognostic (3.70e-2)" MTHFS HsT19268 ENSG00000136371 "Methenyltetrahydrofolate synthetase" P49914 15 79833585-79897379 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Ligase "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "liver: 168.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 191.4;Megakaryocytes: 129.8;Neutrophils: 132.6;Syncytiotrophoblasts: 352.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 129.0" "Group enriched" "Detected in all" 5 "granulocytes: 129.0;monocytes: 48.9" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Stomach - Mitotic cells (Stomach), Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008067, HPA054177" Approved Supported Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 25: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 3 Cytosol "HPA008067: , HPA054177: " "unprognostic (4.49e-2)" "unprognostic (1.88e-1)" "unprognostic (2.77e-2)" "potential prognostic favorable (6.60e-4)" "unprognostic (1.14e-1)" "unprognostic (1.30e-1)" "potential prognostic unfavorable (1.21e-4)" "unprognostic (3.56e-1)" "potential prognostic unfavorable (6.09e-4)" "unprognostic (7.79e-3)" "unprognostic (1.86e-3)" "unprognostic (1.62e-1)" "unprognostic (1.03e-1)" "unprognostic (1.75e-3)" "unprognostic (1.50e-1)" "unprognostic (1.84e-3)" "unprognostic (1.75e-1)" "unprognostic (4.36e-2)" "unprognostic (7.44e-2)" "unprognostic (9.70e-2)" "unprognostic (8.91e-2)" "unprognostic (4.13e-2)" "unprognostic (2.56e-1)" "unprognostic (2.84e-2)" "unprognostic (3.14e-1)" "unprognostic (9.90e-2)" "unprognostic (1.09e-2)" "unprognostic (1.25e-2)" "unprognostic (7.98e-2)" "unprognostic (1.57e-1)" "unprognostic (5.00e-2)" MTHFSD FLJ12998 ENSG00000103248 "Methenyltetrahydrofolate synthetase domain containing" Q2M296 16 86530178-86555235 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041333 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 39: Testis - Nuclear processes" "Cluster 11: White matter - Signal transduction" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Transcription" "Nucleoplasm, Vesicles" "HPA041333: " "unprognostic (5.46e-2)" "unprognostic (1.50e-2)" "unprognostic (4.31e-1)" "unprognostic (2.70e-2)" "unprognostic (1.79e-2)" "unprognostic (2.35e-1)" "unprognostic (2.00e-1)" "potential prognostic favorable (9.12e-6)" "unprognostic (3.47e-1)" "unprognostic (2.74e-1)" "potential prognostic favorable (4.55e-4)" "unprognostic (8.14e-2)" "potential prognostic favorable (1.73e-5)" "unprognostic (1.07e-2)" "unprognostic (1.36e-1)" "unprognostic (1.15e-1)" "potential prognostic unfavorable (1.05e-4)" "unprognostic (5.28e-2)" "unprognostic (5.61e-2)" "unprognostic (1.94e-1)" "unprognostic (1.39e-1)" "unprognostic (8.45e-2)" "potential prognostic unfavorable (7.23e-4)" "potential prognostic unfavorable (2.80e-4)" "unprognostic (1.32e-1)" "unprognostic (4.65e-3)" "unprognostic (3.90e-2)" "unprognostic (2.66e-1)" "unprognostic (2.57e-1)" "unprognostic (1.19e-1)" "unprognostic (2.47e-1)" MTIF2 IF-2mt ENSG00000085760 "Mitochondrial translational initiation factor 2" P46199 2 55236595-55269347 "Essential proteins, Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006021, HPA061422" Approved Supported Mitochondria NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 97: Non-specific - Cellular respiration" 72 Mitochondria "HPA006021: , HPA061422: " "unprognostic (8.03e-2)" "unprognostic (7.68e-2)" "unprognostic (1.08e-1)" "unprognostic (1.28e-1)" "unprognostic (1.30e-1)" "unprognostic (1.32e-2)" "unprognostic (5.48e-2)" "unprognostic (2.70e-1)" "unprognostic (6.28e-2)" "unprognostic (3.69e-2)" "unprognostic (2.28e-3)" "unprognostic (4.53e-1)" "unprognostic (2.04e-1)" "unprognostic (6.92e-3)" "potential prognostic unfavorable (1.80e-4)" "unprognostic (1.98e-3)" "unprognostic (5.46e-2)" "unprognostic (1.28e-2)" "unprognostic (5.20e-2)" "unprognostic (1.54e-1)" "unprognostic (3.30e-3)" "unprognostic (3.05e-3)" "unprognostic (3.55e-2)" "unprognostic (1.03e-1)" "unprognostic (2.60e-2)" "unprognostic (4.38e-1)" "unprognostic (2.34e-2)" "unprognostic (7.15e-2)" "unprognostic (1.54e-1)" "unprognostic (8.37e-3)" "unprognostic (1.12e-1)" MTIF3 "IF-3mt, IF3(mt)" ENSG00000122033 "Mitochondrial translational initiation factor 3" Q9H2K0 13 27435643-27450591 "Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 634.2;Esophageal apical cells: 381.5;Late primary spermatocytes: 603.9;Oocytes: 773.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039791 Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 52: Non-specific - Cellular respiration" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 64 Mitochondria Nucleoplasm "HPA039791: " "unprognostic (6.34e-2)" "unprognostic (3.50e-1)" "unprognostic (1.88e-1)" "unprognostic (2.20e-1)" "unprognostic (6.18e-2)" "unprognostic (1.32e-2)" "unprognostic (8.25e-2)" "unprognostic (1.67e-1)" "unprognostic (5.04e-2)" "unprognostic (3.60e-2)" "unprognostic (1.79e-3)" "unprognostic (3.10e-2)" "potential prognostic favorable (2.96e-6)" "unprognostic (3.18e-1)" "unprognostic (2.91e-2)" "unprognostic (2.64e-1)" "unprognostic (2.23e-1)" "unprognostic (1.71e-1)" "unprognostic (2.14e-1)" "unprognostic (1.13e-1)" "potential prognostic unfavorable (9.29e-4)" "unprognostic (9.20e-2)" "unprognostic (1.63e-1)" "unprognostic (2.80e-1)" "unprognostic (4.94e-2)" "unprognostic (3.25e-1)" "unprognostic (4.02e-2)" "unprognostic (4.67e-2)" "unprognostic (2.24e-2)" "unprognostic (1.03e-1)" "unprognostic (1.41e-1)" MTLN "LEMP, LINC00116, MOXI, MPM, NCRNA00116, SMIM37" ENSG00000175701 Mitoregulin Q8NCU8 2 110211529-110245420 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "heart muscle: 232.8;skeletal muscle: 736.2;tongue: 262.1" "Cell type enhanced" "Detected in many" "Hepatocytes: 270.9;Megakaryocytes: 210.2;Parietal cells: 284.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 45: Non-specific - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 97: Non-specific - Cellular respiration" "unprognostic (1.44e-1)" "unprognostic (2.08e-1)" "unprognostic (2.42e-1)" "unprognostic (2.33e-1)" "unprognostic (2.73e-2)" "unprognostic (1.24e-1)" "unprognostic (1.44e-1)" "unprognostic (3.61e-1)" "unprognostic (1.88e-1)" "unprognostic (3.13e-2)" "unprognostic (6.10e-2)" "unprognostic (2.07e-1)" "unprognostic (1.97e-3)" "unprognostic (1.54e-1)" "unprognostic (2.17e-1)" "unprognostic (3.47e-2)" "unprognostic (5.82e-2)" "unprognostic (2.35e-1)" "unprognostic (3.39e-1)" "unprognostic (2.81e-3)" "unprognostic (1.90e-1)" "unprognostic (1.20e-1)" "unprognostic (4.30e-2)" "unprognostic (5.00e-2)" "unprognostic (1.38e-1)" "unprognostic (1.08e-1)" "unprognostic (1.29e-1)" "unprognostic (2.86e-1)" "unprognostic (4.44e-2)" MTM1 ENSG00000171100 "Myotubularin 1" Q13496 X 150568417-150673143 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Protein transport, Transport" "Hydrolase, Protein phosphatase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Sertoli cells: 189.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010008, HPA010665" Approved Supported "Plasma membrane" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 39: Astrocytes - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 7: Non-specific - Transcription" 11 "Plasma membrane" "HPA010008: , HPA010665: " "unprognostic (8.14e-3)" "unprognostic (1.41e-2)" "unprognostic (2.82e-1)" "unprognostic (2.12e-2)" "unprognostic (2.16e-2)" "unprognostic (2.81e-1)" "unprognostic (1.96e-1)" "unprognostic (1.74e-1)" "unprognostic (5.41e-2)" "unprognostic (2.35e-2)" "potential prognostic favorable (1.58e-7)" "unprognostic (6.22e-2)" "unprognostic (5.71e-2)" "unprognostic (2.20e-1)" "unprognostic (2.27e-1)" "unprognostic (1.30e-1)" "unprognostic (5.52e-2)" "unprognostic (1.96e-1)" "unprognostic (1.74e-1)" "unprognostic (1.89e-1)" "unprognostic (5.71e-2)" "unprognostic (1.37e-2)" "unprognostic (2.94e-1)" "unprognostic (1.19e-1)" "unprognostic (1.70e-2)" "unprognostic (1.14e-1)" "unprognostic (3.00e-1)" "unprognostic (9.11e-2)" "unprognostic (2.04e-1)" "unprognostic (1.01e-1)" "unprognostic (6.11e-2)" MTMR1 ENSG00000063601 "Myotubularin related protein 1" Q13613 X 150692971-150765108 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018502, HPA075953" Approved Approved Vesicles NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 29: Forebrain - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 51: Secretory epithelial cells - Mixed function" 20 Vesicles "HPA018502: , HPA075953: " "unprognostic (4.71e-1)" "unprognostic (5.97e-2)" "unprognostic (2.36e-1)" "unprognostic (1.71e-1)" "unprognostic (1.54e-1)" "unprognostic (2.58e-2)" "unprognostic (2.07e-2)" "potential prognostic favorable (2.18e-4)" "unprognostic (4.15e-2)" "unprognostic (1.21e-2)" "potential prognostic favorable (7.51e-5)" "unprognostic (1.84e-1)" "unprognostic (1.33e-1)" "unprognostic (1.58e-1)" "unprognostic (8.09e-2)" "unprognostic (1.67e-1)" "unprognostic (3.00e-2)" "unprognostic (8.94e-2)" "unprognostic (5.68e-2)" "unprognostic (1.07e-1)" "unprognostic (9.09e-3)" "unprognostic (1.46e-1)" "unprognostic (5.89e-3)" "unprognostic (1.97e-2)" "unprognostic (9.32e-3)" "unprognostic (1.65e-1)" "unprognostic (6.17e-2)" "unprognostic (1.36e-2)" "unprognostic (1.40e-1)" "unprognostic (3.02e-1)" "unprognostic (2.86e-1)" MTMR10 FLJ20313 ENSG00000166912 "Myotubularin related protein 10" Q9NXD2 15 30938941-30991628 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 77.6" "Cell type enhanced" "Detected in many" "Astrocytes: 107.9;Bergmann glia: 88.9;Choroid plexus epithelial cells: 80.6;Distal convoluted tubule cells: 142.9;Loop of henle epithelial cells: 130.7;Microglia: 115.6;Oligodendrocytes: 159.3;Papillary tip epithelial cells: 62.6;Podocytes: 95.5;Proximal tubule cells: 103.2;Renal collecting duct intercalated cells: 115.7;Renal collecting duct principal cells: 177.0;Renal connecting tubule cells: 223.6" "Cell type enhanced" "Detected in all" "oligodendrocyte: 242.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 13.6" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006081 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" No No "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 15: Kidney cancer - Membrane components" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 2 "Nucleoplasm, Nuclear bodies" Cytosol "HPA006081: " "unprognostic (6.53e-2)" "unprognostic (1.14e-1)" "unprognostic (1.91e-3)" "unprognostic (6.37e-2)" "unprognostic (6.62e-2)" "unprognostic (2.10e-1)" "unprognostic (5.62e-2)" "unprognostic (2.62e-1)" "unprognostic (3.75e-2)" "unprognostic (1.34e-1)" "validated prognostic favorable (7.49e-8)" "validated prognostic favorable (2.66e-5)" "unprognostic (4.42e-3)" "unprognostic (1.60e-1)" "unprognostic (1.20e-1)" "unprognostic (4.28e-2)" "unprognostic (4.81e-2)" "unprognostic (1.64e-2)" "unprognostic (8.26e-2)" "unprognostic (2.54e-2)" "unprognostic (1.35e-1)" "unprognostic (6.73e-2)" "unprognostic (3.32e-1)" "unprognostic (2.23e-1)" "unprognostic (1.73e-2)" "unprognostic (3.99e-2)" "unprognostic (1.53e-1)" "unprognostic (1.37e-1)" "unprognostic (1.88e-1)" "unprognostic (1.40e-1)" "potential prognostic unfavorable (9.01e-4)" MTMR11 CRA ENSG00000014914 "Myotubularin related protein 11" A4FU01 1 149928651-149936879 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Colonocytes: 118.3;Enteric stem cells: 51.3;Enteric transient amplifying cells: 46.7;Enterocytes: 129.3;Gastric progenitor cells: 50.0;Goblet cells: 105.8;Paneth cells: 46.4;Sertoli cells: 38.7;Syncytiotrophoblasts: 35.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.3;myeloid DC: 1.7;non-classical monocyte: 1.3" "Group enriched" "Detected in many" 16 "dendritic cells: 1.7;monocytes: 1.3" "Low cancer specificity" "Detected in many" "Prostate - Fibroblasts, Spleen - Fibroblasts_1, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030351, HPA072906" Enhanced Approved Centrosome NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 77: Intestine - Digestion" "Cluster 3: Choroid plexus - Cilium" "Cluster 5: Rhabdoid - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" Centrosome "HPA030351: , HPA072906: " "unprognostic (6.02e-2)" "unprognostic (4.13e-1)" "unprognostic (3.53e-1)" "potential prognostic unfavorable (7.17e-4)" "unprognostic (8.49e-3)" "unprognostic (4.93e-3)" "unprognostic (2.06e-1)" "unprognostic (1.86e-1)" "unprognostic (3.42e-1)" "validated prognostic favorable (2.27e-8)" "validated prognostic favorable (9.02e-5)" "unprognostic (3.15e-1)" "unprognostic (3.93e-3)" "unprognostic (5.20e-2)" "unprognostic (1.71e-1)" "potential prognostic unfavorable (2.50e-4)" "unprognostic (5.13e-2)" "unprognostic (1.07e-1)" "unprognostic (4.77e-2)" "unprognostic (5.19e-2)" "unprognostic (4.04e-2)" "unprognostic (2.11e-1)" "unprognostic (3.27e-1)" "unprognostic (4.66e-2)" "unprognostic (8.32e-3)" "unprognostic (1.06e-2)" "unprognostic (5.05e-2)" "unprognostic (1.06e-1)" "unprognostic (2.82e-2)" "unprognostic (1.31e-2)" MTMR12 "3-PAP, 3PAP, FLJ20476, KIAA1682, PIP3AP" ENSG00000150712 "Myotubularin related protein 12" Q9C0I1 5 32226994-32312987 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Megakaryocytes: 210.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051333 Supported NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 61: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 51: Secretory epithelial cells - Mixed function" 6 "HPA051333: " "unprognostic (3.12e-1)" "unprognostic (5.39e-2)" "unprognostic (1.88e-2)" "unprognostic (7.54e-2)" "unprognostic (3.03e-1)" "unprognostic (2.78e-1)" "unprognostic (5.53e-2)" "unprognostic (2.30e-1)" "unprognostic (1.27e-2)" "unprognostic (1.71e-2)" "potential prognostic favorable (6.51e-8)" "unprognostic (1.06e-2)" "unprognostic (1.09e-1)" "unprognostic (5.16e-2)" "unprognostic (4.96e-1)" "unprognostic (2.57e-2)" "unprognostic (3.38e-2)" "unprognostic (1.71e-1)" "unprognostic (2.62e-2)" "unprognostic (3.79e-1)" "unprognostic (2.16e-1)" "unprognostic (1.74e-1)" "unprognostic (1.38e-2)" "unprognostic (1.25e-1)" "unprognostic (7.36e-3)" "unprognostic (3.64e-1)" "unprognostic (3.29e-1)" "unprognostic (5.37e-2)" "unprognostic (2.05e-1)" "unprognostic (1.68e-1)" "unprognostic (6.27e-2)" MTMR14 "C3orf29, FLJ22405, FLJ90311, hEDTP, hJumpy" ENSG00000163719 "Myotubularin related protein 14" Q8NCE2 3 9649433-9702393 "Disease related genes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 216.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054063 Approved NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 52: Non-specific - Cellular respiration" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 55: Lymphoma - Immune response" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 7 "HPA054063: " "unprognostic (1.06e-1)" "unprognostic (2.21e-2)" "unprognostic (1.01e-1)" "unprognostic (7.80e-2)" "unprognostic (1.68e-1)" "unprognostic (6.78e-2)" "unprognostic (1.39e-2)" "potential prognostic favorable (7.23e-4)" "unprognostic (1.01e-2)" "unprognostic (8.73e-3)" "potential prognostic favorable (9.99e-5)" "unprognostic (7.70e-2)" "potential prognostic favorable (8.49e-4)" "unprognostic (3.49e-3)" "potential prognostic unfavorable (6.21e-4)" "unprognostic (4.62e-3)" "unprognostic (3.85e-2)" "unprognostic (2.34e-2)" "unprognostic (1.46e-1)" "unprognostic (2.14e-3)" "unprognostic (3.47e-2)" "unprognostic (8.15e-2)" "unprognostic (1.47e-1)" "unprognostic (1.94e-1)" "unprognostic (2.48e-2)" "unprognostic (4.50e-3)" "unprognostic (4.58e-1)" "unprognostic (1.59e-1)" "unprognostic (2.68e-1)" "unprognostic (2.21e-2)" "unprognostic (1.77e-1)" MTMR2 "CMT4B, KIAA1073" ENSG00000087053 "Myotubularin related protein 2" Q13614 11 95821766-95925315 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" Hydrolase "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 217.7;Oligodendrocytes: 258.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049831 Approved Supported Vesicles NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 28 Vesicles "HPA049831: " "unprognostic (2.52e-1)" "unprognostic (5.49e-3)" "unprognostic (9.31e-2)" "unprognostic (2.72e-3)" "unprognostic (6.75e-2)" "unprognostic (3.16e-1)" "unprognostic (4.91e-2)" "unprognostic (6.12e-2)" "unprognostic (3.95e-2)" "unprognostic (1.95e-2)" "potential prognostic favorable (2.24e-8)" "unprognostic (2.30e-2)" "unprognostic (4.72e-2)" "potential prognostic unfavorable (3.93e-8)" "unprognostic (2.71e-2)" "potential prognostic unfavorable (6.49e-5)" "unprognostic (3.14e-2)" "unprognostic (3.98e-1)" "unprognostic (2.46e-1)" "unprognostic (7.42e-2)" "unprognostic (3.89e-1)" "unprognostic (4.14e-3)" "unprognostic (8.04e-2)" "unprognostic (1.49e-1)" "unprognostic (1.15e-1)" "unprognostic (2.57e-1)" "unprognostic (8.43e-2)" "unprognostic (6.81e-2)" "unprognostic (1.09e-1)" "unprognostic (5.22e-2)" "unprognostic (2.98e-1)" MTMR3 "FYVE-DSP1, KIAA0371, ZFYVE10" ENSG00000100330 "Myotubularin related protein 3" Q13615 22 29883169-30030868 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 77.1" "Group enriched" "Detected in all" 4 "Neutrophil progenitors: 1205.0;Neutrophils: 2562.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034515, HPA034516" Uncertain Uncertain Nucleoplasm,Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 21 Nucleoplasm Cytosol "HPA034515: , HPA034516: " "unprognostic (1.76e-1)" "unprognostic (1.14e-1)" "unprognostic (1.05e-1)" "unprognostic (1.03e-1)" "unprognostic (1.13e-1)" "unprognostic (1.40e-1)" "unprognostic (8.86e-2)" "unprognostic (8.50e-2)" "unprognostic (2.88e-2)" "unprognostic (3.36e-2)" "validated prognostic favorable (7.34e-6)" "validated prognostic favorable (4.50e-5)" "unprognostic (4.51e-3)" "unprognostic (1.14e-2)" "unprognostic (1.60e-1)" "unprognostic (5.25e-2)" "unprognostic (5.42e-2)" "unprognostic (5.23e-3)" "unprognostic (9.35e-3)" "unprognostic (5.65e-2)" "unprognostic (6.29e-2)" "unprognostic (1.83e-1)" "unprognostic (8.32e-3)" "unprognostic (2.74e-1)" "unprognostic (6.44e-3)" "unprognostic (1.29e-1)" "unprognostic (1.09e-1)" "unprognostic (1.88e-1)" "unprognostic (1.78e-1)" "unprognostic (2.42e-2)" "unprognostic (6.95e-2)" MTMR4 "KIAA0647, ZFYVE11" ENSG00000108389 "Myotubularin related protein 4" Q9NYA4 17 58489529-58517905 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Sertoli cells: 117.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 36: Brain & Liver - Signaling" "Cluster 49: Hindbrain - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 32 "unprognostic (4.88e-2)" "unprognostic (4.51e-1)" "unprognostic (4.03e-1)" "potential prognostic unfavorable (5.48e-4)" "unprognostic (9.86e-2)" "unprognostic (3.67e-1)" "unprognostic (4.05e-1)" "potential prognostic favorable (1.71e-4)" "unprognostic (6.81e-2)" "potential prognostic unfavorable (2.28e-4)" "unprognostic (1.28e-1)" "unprognostic (1.62e-2)" "unprognostic (3.14e-1)" "unprognostic (3.92e-2)" "unprognostic (1.62e-1)" "unprognostic (1.40e-2)" "unprognostic (1.26e-1)" "unprognostic (4.93e-2)" "unprognostic (1.34e-2)" "unprognostic (1.49e-1)" "unprognostic (1.06e-1)" "unprognostic (2.15e-3)" "unprognostic (1.59e-1)" "unprognostic (2.58e-1)" "potential prognostic favorable (5.19e-4)" "unprognostic (1.01e-1)" "unprognostic (1.82e-1)" "unprognostic (1.89e-1)" "unprognostic (3.59e-1)" "unprognostic (4.85e-2)" "unprognostic (4.14e-2)" MTMR6 ENSG00000139505 "Myotubularin related protein 6" Q9Y217 13 25246222-25287510 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Endocytosis, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophil progenitors: 148.2;Neutrophils: 342.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 8 "potential prognostic favorable (6.14e-4)" "unprognostic (1.29e-1)" "unprognostic (5.22e-1)" "unprognostic (1.27e-2)" "unprognostic (9.96e-2)" "unprognostic (3.88e-2)" "unprognostic (2.82e-1)" "unprognostic (2.80e-1)" "unprognostic (2.47e-1)" "unprognostic (2.41e-3)" "potential prognostic favorable (1.82e-9)" "unprognostic (6.49e-3)" "potential prognostic favorable (5.59e-4)" "unprognostic (4.87e-1)" "unprognostic (1.35e-1)" "unprognostic (1.06e-1)" "unprognostic (1.07e-2)" "unprognostic (2.30e-1)" "unprognostic (1.15e-1)" "unprognostic (5.41e-3)" "unprognostic (1.55e-3)" "unprognostic (2.70e-1)" "unprognostic (2.20e-2)" "unprognostic (1.89e-1)" "unprognostic (2.67e-2)" "unprognostic (7.58e-2)" "unprognostic (1.37e-1)" "unprognostic (6.39e-2)" "unprognostic (1.67e-1)" "unprognostic (1.29e-2)" "unprognostic (1.54e-1)" MTMR7 ENSG00000003987 "Myotubularin related protein 7" Q9Y216 8 17296794-17413528 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.6;retina: 26.3" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 131.4;Brain inhibitory neurons: 131.3;Cone photoreceptor cells: 163.5;Corticotrophs: 160.8;Epicardial cells: 241.1;Gonadotrophs: 137.9;Lactotrophs: 243.5;Oligodendrocyte progenitor cells: 122.8;Oligodendrocytes: 197.8;Other brain neurons: 117.3;Pancreatic islet cells: 188.6;Retinal amacrine cells: 166.3;Retinal bipolar cells: 102.4;Retinal ganglion cells: 127.5;Retinal horizontal cells: 114.2;Rod photoreceptor cells: 389.9;Somatotrophs: 156.2;Thyrotrophs: 125.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "lymphoma: 6.5" "Adipose visceral - Mesothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075682 Approved Nucleoplasm,Cytosol NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 34: Non-specific - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 79: Photoreceptor cells - Phototransduction" 13 "Nucleoplasm, Cytosol" "HPA075682: " "unprognostic (1.65e-1)" "unprognostic (5.67e-2)" "unprognostic (3.12e-1)" "unprognostic (1.61e-1)" "potential prognostic favorable (7.71e-4)" "unprognostic (7.41e-2)" "unprognostic (2.25e-2)" "unprognostic (1.16e-2)" "unprognostic (7.84e-3)" "unprognostic (1.49e-1)" "potential prognostic favorable (2.56e-4)" "unprognostic (6.43e-2)" "unprognostic (8.44e-2)" "unprognostic (4.28e-2)" "unprognostic (1.61e-1)" "unprognostic (7.60e-2)" "unprognostic (8.62e-2)" MTMR8 FLJ20126 ENSG00000102043 "Myotubularin related protein 8" Q96EF0 X 64268081-64395452 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 66.1;Fibro-adipogenic progenitors: 76.0" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 7: Non-specific - Transcription" 6 "unprognostic (1.20e-1)" "unprognostic (3.11e-2)" "unprognostic (8.87e-2)" "unprognostic (1.78e-3)" "unprognostic (2.56e-1)" MTMR9 "C8orf9, DKFZp434K171, LIP-STYX, MTMR8" ENSG00000104643 "Myotubularin related protein 9" Q96QG7 8 11284816-11328146 "Plasma proteins, Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 41.1;Bergmann glia: 49.1;Brain excitatory neurons: 50.2;Brain inhibitory neurons: 51.9;Choroid plexus epithelial cells: 46.4;Distal convoluted tubule cells: 38.6;Ependymal cells: 27.3;Loop of henle epithelial cells: 31.0;Microglia: 56.0;Oligodendrocyte progenitor cells: 51.8;Oligodendrocytes: 56.4;Other brain neurons: 53.5;Papillary tip epithelial cells: 32.3;Podocytes: 37.2;Proximal tubule cells: 27.0;Renal collecting duct intercalated cells: 39.7;Renal collecting duct principal cells: 32.2;Renal connecting tubule cells: 30.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070944 Approved "Actin filaments,Centrosome" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 40: Non-specific - Unknown function" "Cluster 102: Non-specific - Mixed function" 36 Centrosome "Actin filaments" "HPA070944: " "unprognostic (2.24e-3)" "unprognostic (1.25e-2)" "unprognostic (1.84e-2)" "unprognostic (4.18e-1)" "unprognostic (1.40e-2)" "unprognostic (4.33e-1)" "unprognostic (1.66e-1)" "potential prognostic favorable (1.24e-4)" "unprognostic (6.66e-3)" "unprognostic (1.43e-3)" "potential prognostic favorable (1.65e-5)" "unprognostic (2.78e-3)" "unprognostic (2.76e-2)" "unprognostic (3.60e-3)" "unprognostic (1.94e-1)" "unprognostic (3.25e-1)" "unprognostic (3.96e-1)" "unprognostic (3.24e-1)" "unprognostic (1.93e-1)" "unprognostic (6.88e-2)" "potential prognostic unfavorable (5.09e-4)" "unprognostic (1.52e-1)" "unprognostic (1.37e-2)" "unprognostic (9.14e-2)" "unprognostic (2.49e-1)" "unprognostic (6.69e-3)" "unprognostic (2.23e-1)" "unprognostic (1.92e-1)" "unprognostic (5.05e-2)" "unprognostic (4.83e-2)" "unprognostic (4.23e-1)" MTNR1A MEL-1A-R ENSG00000168412 "Melatonin receptor 1A" P48039 4 186526792-186555567 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "kidney: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Bone cancer: 1.2" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 26 "unprognostic (4.79e-2)" "unprognostic (4.87e-2)" MTNR1B ENSG00000134640 "Melatonin receptor 1B" P49286 11 92969651-92985066 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Brain inhibitory neurons: 1.6;Ependymal cells: 2.3;Syncytiotrophoblasts: 6.8" "Cell type enhanced" "Detected in some" "ependymal cell: 3.5;medium spiny neuron: 2.1;midbrain-derived inhibitory: 5.3" "Cancer enhanced" "Detected in single" "Liver Hepatocellular Carcinoma (TCGA): 1.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 3.8;testis cancer: 1.2" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA074024 Supported NA NA "Cluster 33: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 7 "HPA074024: " "unprognostic (2.68e-2)" "unprognostic (1.48e-1)" MTO1 ENSG00000135297 "Mitochondrial tRNA translation optimization 1" Q9Y2Z2 6 73461578-73509236 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "tRNA processing" "Cardiomyopathy, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 173.3;Late primary spermatocytes: 109.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030230, HPA030232" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 48: Non-specific - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 65: Non-specific - Cell growth & division" 1 Nucleoplasm Cytosol "HPA030230: , HPA030232: " "unprognostic (3.14e-1)" "unprognostic (2.00e-2)" "unprognostic (9.43e-2)" "unprognostic (1.04e-1)" "unprognostic (4.47e-3)" "unprognostic (3.97e-2)" "unprognostic (7.34e-2)" "unprognostic (7.03e-3)" "unprognostic (2.05e-1)" "unprognostic (1.46e-2)" "potential prognostic favorable (2.09e-7)" "unprognostic (4.46e-3)" "unprognostic (2.01e-1)" "unprognostic (1.60e-1)" "unprognostic (1.95e-1)" "unprognostic (1.63e-1)" "unprognostic (2.20e-1)" "unprognostic (1.61e-1)" "unprognostic (2.28e-1)" "unprognostic (2.12e-1)" "unprognostic (7.60e-2)" "unprognostic (3.77e-1)" "unprognostic (3.46e-1)" "unprognostic (1.15e-1)" "unprognostic (1.34e-3)" "unprognostic (3.74e-2)" "unprognostic (2.05e-1)" "unprognostic (1.39e-1)" "unprognostic (3.01e-1)" "unprognostic (6.74e-2)" "unprognostic (2.99e-1)" MTOR "FLJ44809, FRAP, FRAP1, FRAP2, RAFT1, RAPT1" ENSG00000198793 "Mechanistic target of rapamycin kinase" P42345 1 11106535-11262556 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Epilepsy, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB069425, CAB080053, CAB080065, CAB080070, CAB080081, CAB080095, CAB080096, CAB080097" Supported Supported "Golgi apparatus,Cytosol" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 7: Non-specific - Transcription" 150 "Golgi apparatus, Cytosol" "CAB069425: , CAB080053: , CAB080065: , CAB080070: , CAB080081: , CAB080095: , CAB080096: , CAB080097: " "unprognostic (6.92e-2)" "unprognostic (1.55e-1)" "unprognostic (2.78e-1)" "unprognostic (1.51e-1)" "unprognostic (2.83e-2)" "unprognostic (1.84e-2)" "unprognostic (4.46e-2)" "unprognostic (9.82e-3)" "unprognostic (5.57e-2)" "unprognostic (1.35e-1)" "unprognostic (1.59e-2)" "unprognostic (4.09e-2)" "unprognostic (9.36e-3)" "unprognostic (4.39e-2)" "unprognostic (3.09e-2)" "unprognostic (2.17e-1)" "unprognostic (1.61e-1)" "unprognostic (1.23e-1)" "unprognostic (3.68e-2)" "unprognostic (2.52e-2)" "unprognostic (7.53e-2)" "unprognostic (2.86e-1)" "unprognostic (2.87e-1)" "unprognostic (3.65e-1)" "unprognostic (1.35e-1)" "unprognostic (1.16e-2)" "unprognostic (2.62e-1)" "unprognostic (3.05e-1)" "unprognostic (3.97e-1)" "unprognostic (8.73e-2)" "unprognostic (3.60e-1)" MTPAP "FLJ10486, PAPD1, SPAX4, TENT6" ENSG00000107951 "Mitochondrial poly(A) polymerase" Q9NVV4 10 30309801-30374448 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "mRNA processing, Transcription" "Nucleotidyltransferase, RNA-binding, Transferase" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 34.6" "Cell type enhanced" "Detected in many" "Early spermatids: 195.0;Late primary spermatocytes: 108.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038620, HPA058232" Approved Supported Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 15: Bone marrow - Innate immune response" "Cluster 2: Neurons - Nucleosome" "Cluster 52: Non-specific - Mitochondria" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" 36 Mitochondria "Nucleoplasm, Vesicles" "HPA038620: , HPA058232: " "unprognostic (9.87e-2)" "unprognostic (5.23e-2)" "unprognostic (4.76e-2)" "unprognostic (8.54e-3)" "unprognostic (9.89e-2)" "unprognostic (2.02e-1)" "unprognostic (4.47e-3)" "potential prognostic favorable (2.79e-6)" "unprognostic (5.00e-2)" "unprognostic (5.63e-3)" "potential prognostic favorable (6.94e-4)" "unprognostic (4.71e-3)" "unprognostic (2.35e-1)" "potential prognostic unfavorable (1.41e-4)" "unprognostic (4.03e-2)" "unprognostic (4.48e-2)" "unprognostic (4.66e-2)" "unprognostic (1.81e-1)" "unprognostic (4.82e-3)" "unprognostic (1.81e-2)" "unprognostic (5.05e-1)" "potential prognostic unfavorable (3.86e-4)" "unprognostic (2.07e-2)" "unprognostic (1.22e-2)" "unprognostic (2.68e-2)" "unprognostic (1.64e-1)" "unprognostic (4.10e-2)" "unprognostic (3.40e-2)" "unprognostic (3.38e-1)" "unprognostic (1.97e-3)" "unprognostic (9.69e-2)" MTPN "GCDP, MYOTROPHIN, V-1" ENSG00000105887 Myotrophin P58546 7 135926760-135977359 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1408.7;Esophageal suprabasal cells: 512.2;Megakaryocytes: 754.2;Neutrophils: 687.4;Platelets: 1974.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019735 Approved Approved "Plasma membrane,Cytosol" NA NA 15000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 33: Neurons - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 47: Platelets - Hemostasis" 9 "Plasma membrane, Cytosol" "HPA019735: " "unprognostic (3.57e-1)" "unprognostic (1.06e-1)" "unprognostic (1.23e-2)" "unprognostic (4.23e-2)" "unprognostic (6.89e-3)" "unprognostic (1.32e-1)" "unprognostic (5.72e-3)" "unprognostic (3.29e-1)" "potential prognostic unfavorable (1.69e-4)" "potential prognostic favorable (5.25e-7)" "unprognostic (3.79e-2)" "unprognostic (1.51e-1)" "potential prognostic unfavorable (2.67e-4)" "unprognostic (6.40e-3)" "potential prognostic unfavorable (5.23e-4)" "unprognostic (4.93e-3)" "unprognostic (1.60e-1)" "unprognostic (3.03e-1)" "unprognostic (3.47e-1)" "potential prognostic unfavorable (1.73e-4)" "potential prognostic unfavorable (2.05e-4)" "unprognostic (6.26e-2)" "unprognostic (1.22e-1)" "unprognostic (3.42e-1)" "unprognostic (2.51e-1)" "unprognostic (4.08e-2)" "unprognostic (2.65e-1)" "unprognostic (3.14e-1)" "unprognostic (4.15e-2)" "unprognostic (2.26e-1)" MTR cblG ENSG00000116984 "5-methyltetrahydrofolate-homocysteine methyltransferase" Q99707 1 236795260-236921278 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Amino-acid biosynthesis, Methionine biosynthesis" "Methyltransferase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal convoluted tubule cells: 454.8;Renal collecting duct intercalated cells: 835.5;Renal collecting duct principal cells: 503.8;Renal connecting tubule cells: 486.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054915 Approved Approved "Microtubules,Cytokinetic bridge,Primary cilium,Basal body,Cytosol" Yes NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 72: Kidney - Transmembrane transport" "Cluster 30: White matter - Myelination" "Cluster 45: Non-specific - Nuclear processes" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 13 "Microtubules, Primary cilium" "Cytokinetic bridge, Basal body, Cytosol" "HPA054915: " "unprognostic (2.30e-2)" "unprognostic (8.50e-2)" "unprognostic (2.63e-2)" "unprognostic (4.15e-2)" "unprognostic (2.54e-1)" "unprognostic (1.44e-2)" "unprognostic (1.73e-1)" "unprognostic (3.38e-1)" "unprognostic (1.41e-1)" "unprognostic (1.29e-1)" "potential prognostic favorable (7.87e-6)" "unprognostic (3.29e-2)" "unprognostic (8.02e-2)" "unprognostic (1.11e-1)" "unprognostic (9.75e-2)" "unprognostic (1.46e-1)" "unprognostic (1.67e-1)" "unprognostic (3.20e-1)" "unprognostic (9.10e-2)" "unprognostic (2.78e-2)" "unprognostic (5.82e-2)" "unprognostic (4.16e-2)" "unprognostic (3.54e-1)" "unprognostic (1.10e-1)" "unprognostic (3.90e-2)" "unprognostic (6.76e-2)" "unprognostic (1.33e-2)" "unprognostic (1.80e-3)" "unprognostic (4.82e-1)" "unprognostic (2.08e-3)" "unprognostic (8.46e-2)" MTRES1 "C6orf203, HSPC230, PRED31" ENSG00000130349 "Mitochondrial transcription rescue factor 1" Q9P0P8 6 107028199-107051586 "Predicted intracellular proteins" "Transcription, Transcription regulation" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049535 Approved NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 76: Non-specific - Metabolism" "Cluster 16: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 26 "HPA049535: " "unprognostic (2.66e-2)" "unprognostic (1.35e-3)" "unprognostic (3.54e-1)" "unprognostic (2.53e-1)" "unprognostic (4.32e-3)" "unprognostic (1.14e-1)" "unprognostic (4.77e-1)" "unprognostic (2.41e-2)" "unprognostic (4.34e-2)" "potential prognostic favorable (3.50e-4)" "unprognostic (2.66e-3)" "potential prognostic favorable (2.12e-4)" "unprognostic (3.19e-2)" "unprognostic (1.75e-1)" "unprognostic (2.73e-1)" "unprognostic (6.06e-3)" "unprognostic (2.93e-1)" "unprognostic (2.24e-2)" "unprognostic (1.31e-1)" "unprognostic (4.26e-3)" "unprognostic (2.56e-1)" "unprognostic (2.86e-1)" "unprognostic (1.79e-2)" "unprognostic (3.50e-2)" "unprognostic (1.38e-1)" "unprognostic (1.87e-1)" "unprognostic (1.37e-1)" "unprognostic (1.89e-2)" "unprognostic (1.09e-1)" MTREX "Dob1, fSAP118, KIAA0052, Mtr4, SKIV2L2" ENSG00000039123 "Mtr4 exosome RNA helicase" P42285 5 55307989-55425579 "Enzymes, Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, mRNA processing, mRNA splicing, rRNA processing" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037379 Supported Supported Nucleoplasm NA NA 7900 "Cluster 18: Non-specific - Translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 66 Nucleoplasm "HPA037379: " "unprognostic (1.53e-2)" "unprognostic (4.69e-2)" "unprognostic (1.75e-1)" "unprognostic (3.06e-1)" "unprognostic (7.01e-2)" "unprognostic (8.40e-2)" "unprognostic (5.18e-3)" "unprognostic (2.18e-1)" "unprognostic (1.52e-2)" "potential prognostic favorable (1.31e-7)" "unprognostic (4.52e-3)" "unprognostic (1.31e-1)" "unprognostic (1.54e-2)" "unprognostic (2.40e-1)" "unprognostic (1.19e-1)" "unprognostic (1.76e-1)" "unprognostic (5.43e-2)" "unprognostic (1.37e-3)" "unprognostic (3.44e-3)" "unprognostic (8.96e-2)" "unprognostic (5.25e-2)" "unprognostic (1.56e-1)" "unprognostic (5.42e-2)" "unprognostic (1.46e-1)" "unprognostic (1.20e-1)" "unprognostic (7.48e-2)" "unprognostic (2.05e-1)" "unprognostic (3.12e-2)" "unprognostic (2.86e-1)" MTRF1 "MGC47721, MTTRF1, RF1" ENSG00000120662 "Mitochondrial translation release factor 1" O75570 13 41216369-41263577 "Predicted intracellular proteins" "Protein biosynthesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 61.1;Late primary spermatocytes: 67.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043316 Uncertain NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 39: Testis - Nuclear processes" "Cluster 5: Non-specific - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 2 "HPA043316: " "unprognostic (3.76e-1)" "unprognostic (1.61e-1)" "unprognostic (2.53e-1)" "unprognostic (5.85e-2)" "unprognostic (1.86e-1)" "unprognostic (2.37e-2)" "unprognostic (3.21e-1)" "unprognostic (4.07e-2)" "unprognostic (2.90e-2)" "unprognostic (6.40e-3)" "validated prognostic favorable (2.78e-5)" "validated prognostic favorable (7.11e-4)" "potential prognostic favorable (8.98e-4)" "unprognostic (1.91e-1)" "unprognostic (1.00e-1)" "unprognostic (1.35e-1)" "unprognostic (8.99e-2)" "unprognostic (7.55e-2)" "unprognostic (2.74e-2)" "unprognostic (3.50e-2)" "unprognostic (3.07e-2)" "unprognostic (1.17e-1)" "potential prognostic unfavorable (3.16e-4)" "unprognostic (3.29e-1)" "unprognostic (8.65e-3)" "unprognostic (2.61e-1)" "unprognostic (8.08e-2)" "unprognostic (4.22e-2)" "unprognostic (5.17e-1)" "unprognostic (7.55e-2)" "unprognostic (2.82e-1)" MTRF1L "HMRF1L, mtRF1a" ENSG00000112031 "Mitochondrial translation release factor 1 like" Q9UGC7 6 152987362-153002709 "Predicted intracellular proteins" "Protein biosynthesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 74.4;Late spermatids: 75.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036367 Uncertain NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 52: Non-specific - Cellular respiration" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 28: Non-specific - Nuclear processes" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 7 "HPA036367: " "unprognostic (1.55e-3)" "potential prognostic unfavorable (1.74e-5)" "unprognostic (1.57e-2)" "unprognostic (2.69e-2)" "unprognostic (3.77e-2)" "unprognostic (9.38e-2)" "unprognostic (2.02e-2)" "unprognostic (2.87e-3)" "unprognostic (7.28e-3)" "unprognostic (7.51e-2)" "potential prognostic favorable (4.93e-5)" "unprognostic (2.02e-1)" "unprognostic (6.05e-2)" "potential prognostic unfavorable (7.13e-4)" "unprognostic (1.64e-3)" "unprognostic (1.90e-3)" "unprognostic (4.11e-3)" "unprognostic (2.20e-1)" "unprognostic (2.83e-1)" "unprognostic (4.93e-2)" "unprognostic (2.44e-1)" "unprognostic (2.24e-2)" "potential prognostic unfavorable (5.61e-4)" "unprognostic (1.99e-1)" "unprognostic (2.50e-1)" "unprognostic (1.02e-2)" "unprognostic (9.30e-2)" "unprognostic (1.95e-1)" "unprognostic (2.15e-1)" "unprognostic (1.01e-2)" "unprognostic (3.10e-2)" MTRFR "C12orf65, COXPD7, FLJ38663, mtRF-R, SPG55" ENSG00000130921 "Mitochondrial translation release factor in rescue" Q9H3J6 12 123233385-123258079 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein biosynthesis" RNA-binding "Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 55.9" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 140.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057595 Approved Approved Nucleoplasm,Mitochondria,Cytosol No Yes "Cluster 3: Non-specific - Nuclear processes" "Cluster 80: Thymus - Adaptive immune response" "Cluster 9: Non-specific - Receptor signaling" "Cluster 38: Non-specific - Transcription" "Cluster 20: Non-specific - Transcription regulation" 4 "Nucleoplasm, Cytosol" Mitochondria "HPA057595: " "unprognostic (4.06e-2)" "unprognostic (6.07e-2)" "unprognostic (7.01e-2)" "unprognostic (3.59e-1)" "unprognostic (1.02e-1)" "unprognostic (1.74e-1)" "unprognostic (8.82e-2)" "potential prognostic favorable (1.07e-4)" "unprognostic (2.06e-1)" "unprognostic (6.43e-3)" "unprognostic (1.05e-2)" "unprognostic (9.24e-2)" "unprognostic (2.46e-1)" "validated prognostic unfavorable (4.05e-6)" "validated prognostic unfavorable (7.97e-4)" "unprognostic (1.35e-1)" "unprognostic (4.44e-2)" "unprognostic (4.56e-2)" "unprognostic (3.82e-2)" "unprognostic (5.17e-2)" "unprognostic (2.68e-1)" "unprognostic (4.04e-2)" "unprognostic (3.57e-3)" "potential prognostic unfavorable (3.35e-5)" "unprognostic (1.96e-1)" "unprognostic (5.26e-2)" "unprognostic (9.75e-2)" "unprognostic (1.84e-1)" "unprognostic (3.12e-2)" "unprognostic (2.03e-2)" "unprognostic (1.14e-1)" MTRR cblE ENSG00000124275 "5-methyltetrahydrofolate-homocysteine methyltransferase reductase" Q9UBK8 5 7851186-7906025 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Methionine biosynthesis" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 105.7;Late spermatids: 219.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038113 Supported Approved "Nucleoplasm,Intermediate filaments,Cytosol" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 29: Non-specific - Unknown function" "Cluster 81: Alveolar cells - Lung function" 1 "Nucleoplasm, Cytosol" "Intermediate filaments" "HPA038113: " "unprognostic (9.86e-3)" "unprognostic (2.03e-2)" "unprognostic (1.85e-1)" "unprognostic (2.02e-1)" "unprognostic (4.71e-2)" "unprognostic (9.19e-2)" "unprognostic (5.34e-1)" "unprognostic (8.61e-2)" "unprognostic (1.13e-1)" "unprognostic (6.58e-2)" "potential prognostic favorable (1.32e-7)" "unprognostic (5.65e-2)" "unprognostic (4.34e-1)" "unprognostic (2.82e-2)" "unprognostic (1.38e-1)" "unprognostic (6.05e-2)" "unprognostic (9.72e-2)" "unprognostic (2.88e-2)" "unprognostic (3.83e-1)" "unprognostic (9.23e-2)" "unprognostic (8.93e-2)" "unprognostic (5.77e-2)" "unprognostic (1.18e-2)" "unprognostic (8.72e-2)" "unprognostic (5.23e-2)" "unprognostic (3.02e-1)" "unprognostic (1.35e-1)" "unprognostic (9.08e-2)" "unprognostic (2.63e-1)" "unprognostic (1.11e-1)" "unprognostic (2.63e-2)" MTSS1 "KIAA0429, MIM, MIMA, MIMB" ENSG00000170873 "MTSS I-BAR domain containing 1" O43312 8 124550784-124728473 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Kupffer cells: 1042.3;monocytes: 687.7;Oligodendrocyte progenitor cells: 658.6;Podocytes: 1518.9" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 95.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 169.7" "Group enriched" "Detected in all" 5 "B-cells: 50.6;monocytes: 169.7" "Cancer enhanced" "Detected in all" "thyroid cancer: 46.4" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Pituitary gland - Undifferentiated cells (Pituitary gland)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019613, HPA064003, HPA075540" Approved Supported Approved "Plasma membrane,Cytosol" NA NA 54000 "Cluster 40: Monocytes - Innate immune response" "Cluster 76: Non-specific - Metabolism" "Cluster 25: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 5 "Plasma membrane, Cytosol" "HPA019613: , HPA064003: , HPA075540: " "unprognostic (3.73e-3)" "unprognostic (6.71e-2)" "unprognostic (5.47e-1)" "unprognostic (1.07e-2)" "unprognostic (6.17e-2)" "unprognostic (4.90e-2)" "unprognostic (1.25e-1)" "potential prognostic favorable (4.69e-5)" "unprognostic (3.31e-1)" "unprognostic (8.84e-3)" "validated prognostic favorable (7.31e-11)" "validated prognostic favorable (4.72e-4)" "unprognostic (8.89e-2)" "unprognostic (3.20e-2)" "unprognostic (7.61e-2)" "unprognostic (2.57e-2)" "unprognostic (4.51e-2)" "unprognostic (1.89e-1)" "unprognostic (4.07e-2)" "unprognostic (1.72e-1)" "unprognostic (8.51e-2)" "unprognostic (2.16e-1)" "unprognostic (8.39e-3)" "unprognostic (1.96e-1)" "unprognostic (1.87e-2)" "unprognostic (8.14e-3)" "unprognostic (4.62e-2)" "unprognostic (5.12e-2)" "unprognostic (1.99e-1)" "unprognostic (2.17e-1)" "unprognostic (2.49e-1)" MTSS2 "ABBA, ABBA-1, LOC92154, MTSS1L" ENSG00000132613 "MTSS I-BAR domain containing 2" Q765P7 16 70661204-70686053 "Predicted intracellular proteins" Actin-binding "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 289.4" "Cell type enhanced" "Detected in many" "Astrocytes: 276.4;Bergmann glia: 468.7;Ependymal cells: 139.7;Extravillous trophoblasts: 145.8;Oligodendrocyte progenitor cells: 290.7" "Cell type enhanced" "Detected in all" "astrocyte: 275.9;Bergmann glia: 459.0;oligodendrocyte precursor cell: 310.6" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 210.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048531, HPA066469" Approved Supported "Focal adhesion sites" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 44: Non-specific - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 28: Astrocytes - Homeostasis & neuron support" 5 "Focal adhesion sites" "HPA048531: , HPA066469: " "unprognostic (6.84e-2)" "unprognostic (1.58e-2)" "unprognostic (9.98e-2)" "unprognostic (2.21e-1)" "unprognostic (2.04e-1)" "unprognostic (2.74e-1)" "unprognostic (1.81e-3)" "unprognostic (3.01e-1)" "unprognostic (6.46e-2)" "unprognostic (3.52e-3)" "unprognostic (1.69e-1)" "potential prognostic unfavorable (1.71e-4)" "unprognostic (1.44e-1)" "unprognostic (8.03e-2)" "unprognostic (2.64e-2)" "unprognostic (1.90e-2)" "unprognostic (1.57e-2)" "unprognostic (1.10e-1)" "unprognostic (4.28e-1)" "unprognostic (6.55e-2)" "unprognostic (2.32e-2)" "unprognostic (9.70e-2)" "unprognostic (7.95e-2)" "unprognostic (7.17e-2)" "unprognostic (5.59e-2)" "unprognostic (1.51e-1)" "unprognostic (3.13e-1)" "unprognostic (1.53e-1)" "unprognostic (1.36e-2)" MTTP "ABL, MTP" ENSG00000138823 "Microsomal triglyceride transfer protein" P55157 4 99564081-99623997 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "Lipid transport, Transport" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 21 "intestine: 259.2;liver: 249.2" "Group enriched" "Detected in many" 4 "Enterocytes: 775.0;Hepatocytes: 326.7" "Group enriched" "Detected in many" 5 "astrocyte: 14.8;Bergmann glia: 9.2;ependymal cell: 30.4" "Cancer enriched" "Detected in many" 9 "Liver Hepatocellular Carcinoma (TCGA): 49.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "Gastric cancer: 5.1;liver cancer: 18.2" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA051170, HPA054862" Uncertain Approved "Endoplasmic reticulum,Cytosol" "Intracellular and membrane" Transport NA NA 730000 "Cluster 77: Intestine - Digestion" "Cluster 39: Astrocytes - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 1: Enterocytes - Absorption and Digestion" 3 "Endoplasmic reticulum, Cytosol" "HPA051170: , HPA054862: " "unprognostic (2.84e-2)" "unprognostic (1.16e-1)" "unprognostic (7.00e-3)" "unprognostic (3.03e-2)" "unprognostic (1.44e-1)" "unprognostic (2.28e-1)" "unprognostic (3.82e-1)" "unprognostic (5.47e-2)" "unprognostic (2.23e-1)" "unprognostic (1.02e-2)" "unprognostic (2.27e-1)" "unprognostic (5.26e-1)" "unprognostic (4.56e-2)" "unprognostic (4.55e-3)" "unprognostic (2.37e-1)" MTURN "C7orf41, Ells1, FLJ25903" ENSG00000180354 "Maturin, neural progenitor differentiation regulator homolog" Q8N3F0 7 30134986-30162762 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 11 "brain: 1847.2" "Cell type enriched" "Detected in many" 4 "Platelets: 1052.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 8.3" "Group enriched" "Detected in many" 5 "granulocytes: 8.3;NK-cells: 2.1" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Minor Salivary Gland - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029507 Enhanced Approved Cytosol NA NA 58000 "Cluster 41: Basophils - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 6: Non-specific - Immune response" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 47: Platelets - Hemostasis" 16 Cytosol "HPA029507: " "unprognostic (1.89e-1)" "unprognostic (2.52e-1)" "unprognostic (6.03e-3)" "unprognostic (4.92e-2)" "unprognostic (1.04e-1)" "unprognostic (2.46e-1)" "unprognostic (4.53e-2)" "unprognostic (1.49e-2)" "unprognostic (1.55e-1)" "validated prognostic favorable (6.56e-10)" "validated prognostic favorable (1.44e-4)" "unprognostic (1.97e-2)" "unprognostic (2.85e-1)" "potential prognostic favorable (4.49e-5)" "unprognostic (2.14e-1)" "unprognostic (1.03e-1)" "unprognostic (1.82e-1)" "unprognostic (1.97e-1)" "unprognostic (1.42e-2)" "unprognostic (1.77e-3)" "unprognostic (3.71e-1)" "unprognostic (8.67e-2)" "unprognostic (4.30e-3)" "unprognostic (1.39e-2)" "unprognostic (4.63e-2)" "unprognostic (1.42e-1)" "unprognostic (2.61e-2)" "unprognostic (3.33e-1)" "unprognostic (4.04e-1)" MTUS1 "ATBP, ATIP1, ATIP3, DKFZp586D1519, FLJ14295, ICIS, KIAA1288, MP44, MTSG1" ENSG00000129422 "Microtubule associated scaffold protein 1" Q9ULD2 8 17643795-17801094 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 717.5;Endometrial glandular cells: 743.8;Endometrial luminal cells: 815.3" "Cell type enhanced" "Detected in all" "endothelial cell: 889.0;oligodendrocyte: 679.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 1.8;naive CD8 T-cell: 1.4" "Lineage enriched" "Detected in single" 19 "T-cells: 1.8" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Skin - Endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067903, HPA069795" Enhanced Nucleoli,Microtubules No No "Cluster 43: Non-specific - Transcription & Translation" "Cluster 70: Non-specific - Protein processing" "Cluster 11: White matter - Signal transduction" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 5 "Nucleoli, Microtubules" "HPA067903: , HPA069795: " "potential prognostic favorable (3.83e-4)" "unprognostic (2.53e-1)" "unprognostic (1.16e-3)" "unprognostic (1.26e-1)" "potential prognostic favorable (1.49e-4)" "unprognostic (6.01e-2)" "unprognostic (2.27e-1)" "unprognostic (6.71e-2)" "unprognostic (3.68e-3)" "potential prognostic unfavorable (4.89e-4)" "validated prognostic favorable (2.23e-5)" "validated prognostic favorable (5.05e-4)" "unprognostic (1.97e-3)" "unprognostic (2.58e-1)" "unprognostic (1.41e-1)" "unprognostic (7.28e-3)" "unprognostic (8.21e-2)" "unprognostic (8.75e-3)" "unprognostic (3.99e-1)" "unprognostic (4.37e-2)" "unprognostic (3.22e-2)" "unprognostic (4.32e-2)" "unprognostic (1.69e-1)" "unprognostic (2.88e-1)" "unprognostic (3.33e-2)" "unprognostic (5.72e-3)" "unprognostic (4.41e-1)" "unprognostic (5.01e-2)" "unprognostic (2.49e-1)" "unprognostic (3.51e-3)" "unprognostic (4.27e-1)" MTUS2 "CAZIP, ICIS, KIAA0774, TIP150" ENSG00000132938 "Microtubule associated scaffold protein 2" Q5JR59 13 28820339-29505947 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "blood vessel: 12.9;heart muscle: 47.0" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 481.8;Brain inhibitory neurons: 560.7;Cardiomyocytes: 1357.5;Choroid plexus epithelial cells: 599.1;Gonadotrophs: 582.1;Lactotrophs: 830.5;Other brain neurons: 367.8;Pituitary stem cells: 317.6;Retinal amacrine cells: 530.1;Retinal bipolar cells: 911.1;Retinal ganglion cells: 529.2;Salivary ionocytes: 524.4;Somatotrophs: 594.3;Thyrotrophs: 597.8;Undifferentiated spermatogonia: 298.5" "Cell type enhanced" "Detected in all" "LAMP5-LHX6 and Chandelier: 1736.6" "Cancer enhanced" "Detected in some" "Bladder Urothelial Carcinoma (TCGA): 2.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 2.5" "Adipose visceral - Mesothelial cells, Breast - Breast myoepithelial cells, Heart muscle - Cardiomyocytes, Kidney - Fibroblasts, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031473, HPA031474, HPA031475" Enhanced Supported "Microtubules,Cytokinetic bridge" Yes NA "Cluster 35: Non-specific - Mixed function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 139 "Microtubules, Cytokinetic bridge" "HPA031473: , HPA031474: , HPA031475: " "unprognostic (8.82e-2)" "unprognostic (1.20e-1)" "unprognostic (2.30e-3)" "unprognostic (1.12e-1)" "unprognostic (2.85e-3)" MTX1 "MTX, MTXN" ENSG00000173171 "Metaxin 1" Q13505 1 155208695-155213824 "Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 8.1;Cardiomyocytes: 19.4;Epicardial cells: 38.7;Kupffer cells: 8.2;Late spermatids: 11.8" "Cell type enhanced" "Detected in some" "Bergmann glia: 3.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Neutrophils_2, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011543 Uncertain Approved Mitochondria NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 8 Mitochondria "HPA011543: " "unprognostic (1.81e-3)" "unprognostic (2.15e-1)" "unprognostic (2.04e-1)" "potential prognostic favorable (1.91e-4)" "unprognostic (4.43e-2)" "unprognostic (3.75e-3)" "unprognostic (4.37e-2)" "unprognostic (1.02e-3)" "unprognostic (6.58e-2)" "unprognostic (2.45e-1)" "unprognostic (1.22e-2)" "unprognostic (1.34e-1)" "unprognostic (1.12e-1)" "unprognostic (5.07e-3)" "unprognostic (1.22e-2)" "unprognostic (1.81e-2)" "unprognostic (2.41e-2)" "unprognostic (1.72e-1)" "unprognostic (2.36e-1)" "unprognostic (4.73e-2)" "unprognostic (2.08e-1)" "unprognostic (1.65e-1)" "unprognostic (1.34e-1)" "unprognostic (1.08e-1)" "unprognostic (4.08e-1)" "unprognostic (1.40e-1)" "unprognostic (6.80e-2)" "unprognostic (2.55e-1)" "unprognostic (2.33e-1)" "unprognostic (2.30e-1)" "unprognostic (9.78e-2)" MTX2 ENSG00000128654 "Metaxin 2" O75431 2 176269395-176338025 "Disease related genes, Predicted intracellular proteins" "Protein transport, Transport" Osteoporosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031550, HPA031551, HPA031552" Approved Approved Supported Nucleoli,Mitochondria NA NA 21000 "Cluster 33: Non-specific - ATP binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 47 Mitochondria Nucleoli "HPA031550: , HPA031551: , HPA031552: " "unprognostic (3.07e-2)" "unprognostic (4.39e-2)" "unprognostic (7.31e-2)" "unprognostic (5.21e-2)" "unprognostic (1.50e-1)" "unprognostic (8.10e-2)" "unprognostic (1.55e-1)" "unprognostic (1.38e-1)" "unprognostic (7.21e-3)" "unprognostic (9.62e-3)" "unprognostic (5.85e-2)" "unprognostic (2.35e-2)" "unprognostic (2.93e-1)" "unprognostic (3.66e-3)" "potential prognostic unfavorable (5.09e-6)" "unprognostic (1.05e-2)" "unprognostic (2.55e-1)" "unprognostic (2.67e-2)" "unprognostic (2.37e-2)" "unprognostic (4.93e-1)" "unprognostic (1.93e-1)" "unprognostic (2.07e-2)" "unprognostic (3.93e-2)" "unprognostic (9.80e-2)" "unprognostic (1.84e-1)" "unprognostic (4.69e-2)" "unprognostic (2.68e-3)" "unprognostic (2.05e-1)" "unprognostic (2.79e-1)" "unprognostic (1.21e-1)" "unprognostic (1.97e-1)" MTX3 ENSG00000177034 "Metaxin 3" Q5HYI7 5 79976716-79991262 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047858, HPA062061" Approved Approved Mitochondria NA NA "Cluster 24: Non-specific - Transcription" "Cluster 65: Brain - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 9 Mitochondria "HPA047858: , HPA062061: " "unprognostic (1.69e-2)" "unprognostic (1.88e-2)" "unprognostic (2.27e-1)" "unprognostic (1.85e-1)" "unprognostic (1.64e-1)" "unprognostic (3.22e-1)" "unprognostic (1.84e-1)" "unprognostic (6.89e-2)" "unprognostic (4.43e-2)" "unprognostic (3.21e-2)" "unprognostic (1.44e-2)" "unprognostic (2.18e-3)" "unprognostic (8.27e-2)" "unprognostic (3.10e-3)" "unprognostic (1.67e-1)" "unprognostic (2.74e-2)" "unprognostic (3.00e-3)" "unprognostic (8.00e-2)" "unprognostic (8.90e-2)" "potential prognostic unfavorable (3.08e-4)" "unprognostic (4.89e-3)" "unprognostic (6.09e-2)" "unprognostic (1.91e-2)" "unprognostic (2.36e-2)" "unprognostic (8.63e-2)" "unprognostic (7.83e-2)" "unprognostic (6.41e-2)" "unprognostic (1.19e-2)" "unprognostic (4.18e-2)" "unprognostic (2.31e-2)" "unprognostic (2.88e-1)" MUC1 "ADMCKD, ADMCKD1, Ca15-3, CD227, EMA, KL-6, MCD, MCKD, MCKD1, PEM, PUM" ENSG00000185499 "Mucin 1, cell surface associated" P15941 1 155185824-155192916 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 416.9;stomach 1: 998.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 192.9;Alveolar cells type 2: 236.0;Breast lactating cells: 217.7;Conjunctival goblet cells: 94.2;Endometrial luminal cells: 102.3;Endometrial secretory cells: 154.6;Foveolar cells: 271.9;Gastric chief cells: 137.6;Mucous neck cells: 117.1;Prostatic club cells: 93.2;Respiratory deuterosomal cells: 126.5;Salivary duct cells: 75.7;Transitional alveolar cells: 176.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.2" "Lineage enhanced" "Detected in single" "T-cells: 1.2" "Cancer enhanced" "Detected in all" "breast cancer: 211.1;pancreatic cancer: 218.2" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Skin - Sebaceous gland cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "CAB000036, CAB001986, HPA004179, HPA007235, HPA008855, CAB080102, CAB080103" Enhanced Supported "Plasma membrane" "Secreted in other tissues" "No annotated function" NA NA 2100000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 60: Stomach - Digestion" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 68: Foveolar cells - Mucosal defense" 29 "Plasma membrane" "CAB000036: , CAB001986: , CAB080102: , CAB080103: , HPA004179: , HPA007235: , HPA008855: " "unprognostic (6.27e-2)" "unprognostic (1.12e-1)" "unprognostic (1.67e-1)" "unprognostic (1.37e-1)" "unprognostic (1.99e-1)" "unprognostic (9.53e-3)" "unprognostic (5.63e-2)" "unprognostic (9.41e-2)" "unprognostic (9.23e-2)" "potential prognostic favorable (8.45e-4)" "potential prognostic unfavorable (6.35e-4)" "unprognostic (2.30e-2)" "unprognostic (1.09e-1)" "unprognostic (3.90e-3)" "unprognostic (2.60e-2)" "unprognostic (3.67e-1)" "unprognostic (2.24e-1)" "unprognostic (5.09e-3)" "unprognostic (9.30e-2)" "unprognostic (1.85e-1)" "unprognostic (1.04e-1)" "potential prognostic unfavorable (4.90e-4)" "unprognostic (1.65e-1)" "unprognostic (4.41e-1)" "unprognostic (5.51e-3)" "unprognostic (3.73e-3)" "unprognostic (2.61e-1)" "unprognostic (1.91e-1)" "unprognostic (1.21e-1)" "unprognostic (4.59e-2)" "unprognostic (9.12e-2)" MUC12 MUC11 ENSG00000205277 "Mucin 12, cell surface associated" Q9UKN1 7 100969565-101018939 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "intestine: 63.6" "Cell type enhanced" "Detected in many" "Colonocytes: 1215.1;Enteric stem cells: 393.8;Enteric transient amplifying cells: 276.2;Enterocytes: 112.4;Goblet cells: 220.4;Paneth cells: 139.2" "Cell type enhanced" "Detected in many" "lower rhombic lip: 9.2" "Group enriched" "Detected in some" 4 "Colon Adenocarcinoma (TCGA): 31.7;Rectum Adenocarcinoma (TCGA): 52.2" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 56 "colorectal cancer: 8.7" "Colon - Colon enterocytes, Testis - Late spermatids" HPA023835 Enhanced NA NA "Cluster 17: Intestine - Digestion" "Cluster 53: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 1 "HPA023835: " "unprognostic (3.84e-2)" "unprognostic (2.37e-2)" "unprognostic (4.47e-3)" "unprognostic (2.27e-2)" "unprognostic (5.06e-2)" "unprognostic (6.76e-2)" "unprognostic (1.41e-1)" "unprognostic (4.83e-2)" MUC13 DRCC1 ENSG00000173702 "Mucin 13, cell surface associated" Q9H3R2 3 124905442-124953819 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "intestine: 579.0" "Cell type enhanced" "Detected in many" "Colonocytes: 1012.6;Endometrial ciliated cells: 205.1;Enteric stem cells: 193.4;Enteric transient amplifying cells: 271.6;Enterocytes: 1143.1;Foveolar cells: 133.2;Gastric progenitor cells: 198.7;Goblet cells: 930.6;Neuroendocrine cells: 200.1;Paneth cells: 147.0" "Low cell type specificity" "Detected in single" "Group enriched" "Detected in many" 4 "Colon Adenocarcinoma (TCGA): 344.5;Pancreatic Adenocarcinoma (TCGA): 110.3;Rectum Adenocarcinoma (TCGA): 380.6;Stomach Adenocarcinoma (TCGA): 260.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 178.0;Gastric cancer: 65.7" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045163, HPA079663" Enhanced "Secreted to digestive system" "No annotated function" NA NA "Cluster 77: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" "HPA045163: , HPA079663: " "potential prognostic favorable (5.10e-5)" "unprognostic (1.81e-2)" "unprognostic (3.84e-1)" "unprognostic (9.07e-2)" "unprognostic (1.51e-3)" "unprognostic (7.66e-2)" "unprognostic (1.37e-1)" "unprognostic (1.08e-1)" "unprognostic (6.74e-2)" "unprognostic (3.23e-2)" "unprognostic (1.49e-1)" "unprognostic (1.22e-1)" "unprognostic (2.27e-1)" "unprognostic (2.79e-1)" "potential prognostic favorable (8.07e-4)" "unprognostic (6.75e-2)" "unprognostic (3.13e-1)" "potential prognostic unfavorable (5.58e-4)" "unprognostic (6.63e-3)" "unprognostic (1.85e-1)" "unprognostic (1.45e-1)" MUC15 ENSG00000169550 "Mucin 15, cell surface associated" Q8N387 11 26559032-26572263 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 26 "epididymis: 1841.3" "Cell type enriched" "Detected in many" 4 "Epididymal principal cells: 5404.7" "Cell type enhanced" "Detected in some" "hippocampal dentate gyrus: 3.7;medium spiny neuron: 4.5" "Cancer enriched" "Detected in many" 8 "Thyroid Carcinoma (TCGA): 85.1" "Region enhanced" "Detected in many" "basal ganglia: 10.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 11.0" "Kidney - Ascending Loop of Henle cells, Prostate - Prostate basal glandular cells, Testis - Early spermatids" "Group enriched" "Detected in some" 4 "cerebellum: 1.2;thalamus: 1.4" "Low region specificity" "Detected in all" "HPA026110, HPA073304" Enhanced "Intracellular and membrane" "No annotated function" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 33: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 3 "HPA026110: , HPA073304: " "unprognostic (6.28e-3)" "unprognostic (2.55e-1)" "unprognostic (1.39e-1)" "unprognostic (1.40e-1)" "unprognostic (1.23e-2)" "unprognostic (1.83e-1)" "unprognostic (4.04e-3)" "unprognostic (2.81e-2)" "unprognostic (1.60e-1)" "unprognostic (3.34e-1)" "unprognostic (1.70e-1)" "unprognostic (1.76e-1)" "unprognostic (2.66e-1)" "validated prognostic unfavorable (5.17e-4)" "validated prognostic unfavorable (7.61e-6)" "unprognostic (1.70e-1)" "potential prognostic unfavorable (9.73e-4)" "unprognostic (1.68e-1)" "unprognostic (8.29e-2)" MUC16 "CA-125, CA125, FLJ14303" ENSG00000181143 "Mucin 16, cell surface associated" Q8WXI7 19 8848844-8981342 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adipose tissue: 6.5;cervix: 15.0;fallopian tube: 5.5;salivary gland: 5.7" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 953.4;Endometrial ciliated cells: 234.4;Endometrial glandular cells: 474.1;Endometrial secretory cells: 428.8;Epicardial cells: 1309.9;Mesothelial cells: 376.1;Ocular epithelial cells: 330.9;Respiratory ciliated cells: 237.8;Respiratory deuterosomal cells: 634.4;Respiratory secretory cells: 435.6;Salivary duct cells: 460.6;Salivary ionocytes: 746.2" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 34.9;Ovary Serous Cystadenocarcinoma (TCGA): 98.0;Uterine Corpus Endometrial Carcinoma (TCGA): 35.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "ovarian cancer: 15.7" "Adipose visceral - Mesothelial cells, Lung - Respiratory ciliated cells, Prostate - Urothelial cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - T-cells" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 1.3" "CAB055172, HPA065600, CAB080360" Enhanced "Secreted in other tissues" "No annotated function" NA NA 140000 "Cluster 75: Ovary - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 51: Secretory epithelial cells - Mixed function" "CAB055172: , CAB080360: , HPA065600: " "unprognostic (2.46e-1)" "unprognostic (1.08e-1)" "unprognostic (8.62e-3)" "unprognostic (1.21e-1)" "unprognostic (1.86e-2)" "unprognostic (1.17e-3)" "unprognostic (1.08e-2)" "unprognostic (6.01e-2)" "unprognostic (8.68e-2)" "unprognostic (9.47e-2)" "unprognostic (4.05e-2)" "validated prognostic unfavorable (7.37e-4)" "validated prognostic unfavorable (8.63e-5)" "unprognostic (1.72e-2)" "unprognostic (2.66e-1)" "unprognostic (3.02e-1)" MUC17 ENSG00000169876 "Mucin 17, cell surface associated" Q685J3 7 101020072-101058859 "Cancer-related genes, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 64 "intestine: 41.4" "Cell type enriched" "Detected in some" 9 "Enterocytes: 1256.4" "Cell type enhanced" "Detected in some" "hippocampal CA4: 2.9;hippocampal dentate gyrus: 3.6" "Cancer enriched" "Detected in some" 5 "Stomach Adenocarcinoma (TCGA): 43.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bile duct cancer: 3.3;colorectal cancer: 5.7;Gastric cancer: 10.4;pancreatic cancer: 4.1" "Colon - Colon enterocytes" "Not detected" "Not detected" "HPA031634, CAB080501, CAB080502, CAB080503" Enhanced "Intracellular and membrane" "No annotated function" NA NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 1: Enterocytes - Absorption and Digestion" "CAB080501: , CAB080502: , CAB080503: , HPA031634: " "unprognostic (3.18e-1)" "unprognostic (1.45e-1)" "unprognostic (5.25e-3)" "unprognostic (2.13e-2)" "unprognostic (1.74e-2)" "unprognostic (4.84e-3)" "unprognostic (1.92e-1)" MUC19 FLJ35746 ENSG00000205592 "Mucin 19, oligomeric" 12 40393395-40570832 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "salivary gland: 3.1" "Cell type enriched" "Detected in some" 10 "Salivary acinar cells: 703.6" "Cell type enhanced" "Detected in some" "eccentric medium spiny neuron: 7.6;upper-layer intratelencephalic: 12.4" "Cancer enhanced" "Detected in single" "Breast Invasive Carcinoma (TCGA): 2.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "breast cancer: 1.3" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 82: Salivary gland - Secretion" "Cluster 27: Breast cancer - Unknown function" "Cluster 38: Secretory epithelial cells - Exocrine secretion" "unprognostic (2.33e-3)" MUC2 ENSG00000198788 "Mucin 2, oligomeric mucus/gel-forming" 11 1074875-1110511 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 40 "intestine: 436.8" "Cell type enriched" "Detected in some" 116 "Goblet cells: 575.2" "Not detected" "Not detected" "Group enriched" "Detected in many" 13 "Colon Adenocarcinoma (TCGA): 241.4;Pancreatic Adenocarcinoma (TCGA): 97.2;Rectum Adenocarcinoma (TCGA): 127.0;Stomach Adenocarcinoma (TCGA): 65.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "breast cancer: 1.6;colorectal cancer: 4.2;Gastric cancer: 2.3" "Colon - Colon enterocytes, Pituitary gland - Corticotropes" "Not detected" "Not detected" CAB016275 Enhanced "Intracellular and membrane" NA NA "Cluster 77: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 70: Intestinal goblet cells - Mucin production" "CAB016275: " "unprognostic (2.37e-3)" "unprognostic (1.10e-1)" "unprognostic (3.31e-1)" "unprognostic (1.23e-1)" "unprognostic (1.19e-2)" "unprognostic (1.48e-3)" "unprognostic (2.43e-2)" "unprognostic (4.28e-2)" "unprognostic (4.03e-3)" "unprognostic (7.38e-2)" "unprognostic (5.13e-2)" "unprognostic (4.93e-3)" "unprognostic (6.81e-2)" MUC20 "FLJ14408, KIAA1359" ENSG00000176945 "Mucin 20, cell surface associated" Q8N307 3 195720884-195741123 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 44.0;kidney: 51.4" "Cell type enhanced" "Detected in some" "Endometrial secretory cells: 7.5;Epididymal clear cells: 6.1;Prostatic club cells: 10.9;Prostatic hillock cells: 7.9;Renal collecting duct intercalated cells: 18.2;Renal collecting duct principal cells: 6.9;Respiratory deuterosomal cells: 24.9;Respiratory ionocytes: 15.2;Respiratory secretory cells: 7.6;Salivary duct cells: 8.2;Salivary ionocytes: 8.3" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in many" 7 "Kidney Chromophobe (TCGA): 270.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 16.8" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA042249 Approved "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to extracellular matrix" "No annotated function" NA NA 310000 "Cluster 72: Kidney - Transmembrane transport" "Cluster 9: Non-specific - Receptor signaling" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA042249: " "unprognostic (9.03e-2)" "unprognostic (1.67e-1)" "unprognostic (4.25e-2)" "unprognostic (1.30e-1)" "unprognostic (3.12e-1)" "unprognostic (2.24e-1)" "unprognostic (3.35e-1)" "unprognostic (5.41e-3)" "unprognostic (1.89e-2)" "unprognostic (3.53e-1)" "validated prognostic favorable (2.73e-4)" "validated prognostic favorable (9.04e-4)" "unprognostic (1.33e-1)" "unprognostic (8.32e-2)" "unprognostic (1.36e-1)" "unprognostic (1.82e-1)" "unprognostic (7.04e-2)" "unprognostic (1.33e-1)" "unprognostic (1.68e-1)" "unprognostic (9.79e-3)" "unprognostic (7.46e-2)" "potential prognostic unfavorable (8.37e-4)" "unprognostic (4.79e-1)" "unprognostic (1.39e-1)" "unprognostic (1.30e-1)" "unprognostic (1.77e-2)" "unprognostic (2.23e-3)" "unprognostic (1.54e-1)" "unprognostic (2.67e-1)" "unprognostic (5.72e-2)" MUC21 "bCX31G15.2, C6orf205" ENSG00000204544 "Mucin 21, cell surface associated" Q5SSG8 6 30983718-30989903 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 170.3;esophagus: 662.0;vagina: 237.8" "Cell type enriched" "Detected in some" 15 "Esophageal apical cells: 101.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Lung Adenocarcinoma (TCGA): 18.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 9 "lung cancer: 2.5" "Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary gland basal cells" "Not detected" "Not detected" HPA052028 Enhanced NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" "HPA052028: " "unprognostic (1.59e-3)" "unprognostic (9.27e-2)" "potential prognostic favorable (7.95e-4)" "unprognostic (2.80e-1)" "unprognostic (1.06e-2)" "unprognostic (1.85e-1)" MUC22 PBMUCL1 ENSG00000261272 "Mucin 22" E2RYF6 6 31010474-31035402 "Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "esophagus: 16.7" "Group enriched" "Detected in some" 7 "Microglia: 5.3;Ocular epithelial cells: 3.0" "Cell type enriched" "Detected in single" 34 "central nervous system macrophage: 7.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes" NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" MUC3A MUC3 ENSG00000169894 "Mucin 3A, cell surface associated" Q02505 7 100949534-100968347 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "gallbladder: 13.0;intestine: 39.4" "Cell type enhanced" "Detected in some" "Colonocytes: 178.5;Enteric stem cells: 162.3;Enteric transient amplifying cells: 108.6;Enterocytes: 386.2;Foveolar cells: 45.7;Goblet cells: 159.1;Paneth cells: 127.6;Pericytes: 63.9;Prostatic glandular cells: 76.2" "Cell type enhanced" "Detected in single" "deep-layer near-projecting: 2.4" "Cancer enhanced" "Detected in many" "Stomach Adenocarcinoma (TCGA): 42.8" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 8.3;Gastric cancer: 3.8" "Region enriched" "Detected in many" 7 "cerebellum: 16.5" "HPA010871, HPA047868" Uncertain Uncertain "Cell Junctions" "Intracellular and membrane" "No annotated function" NA NA "Cluster 77: Intestine - Digestion" "Cluster 1: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "Cell Junctions" "HPA010871: , HPA047868: " "unprognostic (6.41e-2)" "unprognostic (2.87e-2)" "unprognostic (1.95e-1)" "unprognostic (5.98e-2)" "potential prognostic unfavorable (3.04e-4)" "unprognostic (1.86e-2)" "unprognostic (8.57e-3)" "unprognostic (1.52e-1)" "unprognostic (3.00e-3)" "unprognostic (2.15e-2)" "unprognostic (4.81e-2)" "unprognostic (9.41e-2)" "unprognostic (1.41e-1)" "unprognostic (2.51e-1)" "unprognostic (2.87e-1)" "unprognostic (9.72e-2)" "unprognostic (3.26e-1)" "unprognostic (1.03e-2)" MUC4 ENSG00000145113 "Mucin 4, cell surface associated" Q99102 3 195746765-195811973 "Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 18.5;intestine: 31.2;prostate: 14.6;vagina: 14.5" "Cell type enhanced" "Detected in some" "Breast lactating cells: 4.9;Conjunctival goblet cells: 5.8;Endometrial secretory cells: 8.1;Loop of henle epithelial cells: 4.9;Papillary tip epithelial cells: 42.3;Prostatic club cells: 6.7;Prostatic hillock cells: 8.9;Renal collecting duct intercalated cells: 11.5;Renal collecting duct principal cells: 9.6;Respiratory deuterosomal cells: 9.3;Salivary duct cells: 14.1" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 3.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 3.4;head and neck cancer: 4.1;pancreatic cancer: 3.1" "Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Urothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Region enriched" "Detected in single" 18 "basal ganglia: 5.4" "HPA005895, CAB013536" Approved "Secreted in other tissues" "Cell adhesion" NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 1 "CAB013536: , HPA005895: " "unprognostic (1.23e-3)" "unprognostic (3.71e-1)" "unprognostic (6.81e-2)" "unprognostic (8.53e-2)" "unprognostic (4.94e-1)" "unprognostic (2.68e-1)" "unprognostic (7.86e-2)" "unprognostic (5.47e-2)" "unprognostic (8.34e-2)" "unprognostic (1.40e-1)" "unprognostic (1.78e-1)" MUC5AC MUC5 ENSG00000215182 "Mucin 5AC, oligomeric mucus/gel-forming" P98088 11 1157953-1201138 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 102 "stomach 1: 174.8" "Group enriched" "Detected in some" 9 "Conjunctival goblet cells: 78.6;Foveolar cells: 85.5" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Lung Adenocarcinoma (TCGA): 19.6;Pancreatic Adenocarcinoma (TCGA): 23.2;Stomach Adenocarcinoma (TCGA): 70.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 27.8;pancreatic cancer: 16.8" "Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells, Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" "CAB002774, CAB009395, HPA040456, HPA040615, HPA070378, HPA077637" Enhanced Uncertain Vesicles "Secreted to digestive system" "No annotated function" NA NA 1000000 "Cluster 60: Stomach - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 68: Foveolar cells - Mucosal defense" 4 Vesicles "CAB002774: , CAB009395: , HPA040456: , HPA040615: , HPA070378: , HPA077637: " "unprognostic (8.03e-2)" "unprognostic (3.07e-1)" "unprognostic (2.75e-3)" "unprognostic (2.32e-2)" "unprognostic (1.72e-1)" "potential prognostic unfavorable (7.84e-4)" "unprognostic (3.46e-2)" "unprognostic (2.02e-3)" "unprognostic (6.85e-2)" "unprognostic (3.09e-1)" MUC5B "MG1, MUC5" ENSG00000117983 "Mucin 5B, oligomeric mucus/gel-forming" Q9HC84 11 1223066-1262172 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "salivary gland: 2643.1" "Group enriched" "Detected in some" 4 "Conjunctival goblet cells: 784.5;Endometrial secretory cells: 1975.7;Submucosal glandular cells: 1170.9" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 218.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 23.1" "Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Ductal cells, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA008246, CAB009396" Enhanced Supported Vesicles "Secreted in other tissues" "No annotated function" NA NA 5300000 "Cluster 82: Salivary gland - Secretion" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 5 Vesicles "CAB009396: , HPA008246: " "unprognostic (2.48e-2)" "unprognostic (2.38e-1)" "potential prognostic favorable (8.93e-4)" "unprognostic (2.03e-1)" "unprognostic (1.94e-3)" "unprognostic (1.42e-2)" "unprognostic (8.36e-2)" "unprognostic (1.56e-1)" "unprognostic (1.67e-1)" "unprognostic (4.08e-3)" "unprognostic (5.64e-2)" "unprognostic (3.18e-1)" "unprognostic (9.38e-2)" "unprognostic (1.32e-1)" "unprognostic (4.47e-2)" "unprognostic (4.84e-2)" "unprognostic (1.66e-1)" "unprognostic (3.32e-1)" "unprognostic (4.33e-3)" "unprognostic (2.44e-1)" "unprognostic (1.79e-2)" MUC6 ENSG00000184956 "Mucin 6, oligomeric mucus/gel-forming" Q6W4X9 11 1012823-1036718 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "pancreas: 167.2;stomach 1: 397.1" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 4.7;Brain inhibitory neurons: 3.9;Distal convoluted tubule cells: 7.1;Endometrial secretory cells: 3.9;Gastric chief cells: 18.6;Loop of henle epithelial cells: 8.6;Mucous neck cells: 37.6;Pancreatic duct cells: 19.1;Renal collecting duct principal cells: 8.0;Renal connecting tubule cells: 5.4" "Cell type enhanced" "Detected in many" "hippocampal dentate gyrus: 14.5" "Cancer enhanced" "Detected in many" "Pancreatic Adenocarcinoma (TCGA): 16.4;Stomach Adenocarcinoma (TCGA): 8.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in some" 15 "basal ganglia: 25.8" CAB002165 Enhanced "Secreted to digestive system" "No annotated function" NA NA 40000 "Cluster 8: Pancreas - Proteolysis" "Cluster 33: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 97: Non-specific - Cellular respiration" "CAB002165: " "unprognostic (1.09e-3)" "unprognostic (1.51e-1)" "unprognostic (2.54e-1)" "unprognostic (1.82e-1)" "unprognostic (8.24e-3)" "unprognostic (1.09e-1)" "unprognostic (7.07e-3)" "unprognostic (2.57e-1)" "unprognostic (1.50e-1)" "unprognostic (4.17e-2)" "unprognostic (9.42e-2)" "unprognostic (1.22e-1)" MUC7 "FLJ27047, MG2" ENSG00000171195 "Mucin 7, secreted" Q8TAX7 4 70430492-70482997 "Disease related genes, Human disease related genes, Predicted secreted proteins" Asthma "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 912 "salivary gland: 25571.3" "Group enriched" "Detected in some" 26 "Salivary acinar cells: 4907.9;Salivary myoepithelial cells: 1775.1" "Cell type enriched" "Detected in single" 4 "thalamic excitatory: 2.7" "Group enriched" "Detected in some" 11 "Head and Neck Squamous Cell Carcinoma (TCGA): 14.3;Skin Cutaneous Melanoma (TCGA): 4.8" "Region enhanced" "Detected in single" "midbrain: 1.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "skin cancer: 1.4" "Minor Salivary Gland - Minor salivary glandular cells, Skin - Eccrine sweat gland cells" HPA006411 Enhanced "Secreted to digestive system" "No annotated function" NA NA 28000 "Cluster 82: Salivary gland - Secretion" "Cluster 46: Brainstem - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 7 "HPA006411: " "unprognostic (2.67e-1)" "unprognostic (8.44e-2)" MUCL1 SBEM ENSG00000172551 "Mucin like 1" Q96DR8 12 54830518-54896008 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "breast: 3038.8;skin 1: 777.3" "Cell type enriched" "Detected in some" 11 "Breast hormone-responsive cells: 7511.2" "Low cell type specificity" "Detected in some" "Cancer enriched" "Detected in many" 32 "Breast Invasive Carcinoma (TCGA): 1590.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 40 "breast cancer: 270.9" "Prostate - Prostate glandular cells" HPA039093 Enhanced "Secreted in other tissues" "No annotated function" NA NA 880000 "Cluster 55: Breast - Lactation" "Cluster 27: Breast cancer - Unknown function" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 3 "HPA039093: " "unprognostic (1.05e-1)" "unprognostic (1.99e-1)" "unprognostic (3.28e-1)" "unprognostic (1.41e-1)" "unprognostic (1.79e-1)" "unprognostic (4.55e-2)" "unprognostic (1.70e-2)" "unprognostic (7.18e-2)" "unprognostic (4.66e-3)" "unprognostic (1.13e-1)" "unprognostic (4.66e-1)" "unprognostic (1.88e-1)" "unprognostic (1.37e-1)" "unprognostic (7.68e-3)" "unprognostic (1.30e-2)" "unprognostic (2.99e-2)" "unprognostic (2.58e-1)" "unprognostic (4.60e-1)" "unprognostic (1.01e-1)" "unprognostic (2.58e-1)" "unprognostic (5.09e-2)" "unprognostic (8.43e-2)" MUCL3 "bCX105N19.6, C6orf37, DPCR1, PBLT" ENSG00000168631 "Mucin like 3" Q3MIW9 6 30934523-30954221 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "stomach 1: 191.8" "Cell type enriched" "Detected in some" 12 "Foveolar cells: 28.6" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Pancreatic Adenocarcinoma (TCGA): 38.4;Stomach Adenocarcinoma (TCGA): 32.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "ovarian cancer: 11.8;pancreatic cancer: 6.6" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA014036 Enhanced NA NA "Cluster 60: Stomach - Digestion" "Cluster 66: Non-specific - Mitochondria" "Cluster 68: Foveolar cells - Mucosal defense" "HPA014036: " "unprognostic (1.86e-1)" "unprognostic (1.43e-3)" "unprognostic (8.77e-2)" "unprognostic (1.01e-3)" "unprognostic (1.18e-2)" "unprognostic (5.63e-1)" "unprognostic (1.74e-1)" MUL1 "C1orf166, FLJ12875, GIDE, MAPL, MULAN, RNF218" ENSG00000090432 "Mitochondrial E3 ubiquitin protein ligase 1" Q969V5 1 20499448-20508151 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 63.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026827 Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 45: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 20 "Nucleoplasm, Mitochondria, Cytosol" "HPA026827: " "unprognostic (1.21e-1)" "unprognostic (1.10e-1)" "unprognostic (5.52e-3)" "unprognostic (1.84e-2)" "unprognostic (1.50e-2)" "unprognostic (1.62e-1)" "unprognostic (2.75e-2)" "unprognostic (4.56e-2)" "potential prognostic unfavorable (7.06e-4)" "unprognostic (3.42e-2)" "validated prognostic favorable (7.99e-9)" "validated prognostic favorable (2.50e-4)" "potential prognostic favorable (7.69e-4)" "unprognostic (1.17e-3)" "potential prognostic unfavorable (2.37e-4)" "unprognostic (1.26e-1)" "unprognostic (1.02e-1)" "unprognostic (1.51e-2)" "unprognostic (4.55e-1)" "potential prognostic unfavorable (7.86e-4)" "unprognostic (1.30e-1)" "unprognostic (1.23e-1)" "unprognostic (5.83e-2)" "unprognostic (1.32e-1)" "unprognostic (3.27e-2)" "unprognostic (5.81e-2)" "unprognostic (1.90e-1)" "unprognostic (1.69e-1)" "unprognostic (2.75e-2)" "unprognostic (7.64e-3)" "unprognostic (2.16e-1)" MUS81 "FLJ44872, SLX3" ENSG00000172732 "MUS81 structure-specific endonuclease subunit" Q96NY9 11 65857126-65867653 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 86.7;Late spermatids: 263.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059530 Approved Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 24: Non-specific - Unknown function" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 25 "Nucleoli fibrillar center" Nucleoplasm "HPA059530: " "unprognostic (1.71e-1)" "unprognostic (2.25e-1)" "unprognostic (2.50e-2)" "unprognostic (2.12e-1)" "unprognostic (4.09e-2)" "unprognostic (1.70e-1)" "validated prognostic favorable (6.46e-4)" "validated prognostic favorable (3.33e-4)" "unprognostic (1.52e-1)" "unprognostic (2.85e-1)" "unprognostic (1.52e-1)" "unprognostic (3.97e-1)" "unprognostic (1.90e-1)" "potential prognostic unfavorable (6.26e-4)" "unprognostic (1.22e-1)" "unprognostic (3.90e-2)" "unprognostic (3.11e-2)" "unprognostic (2.62e-1)" "unprognostic (3.68e-2)" "unprognostic (2.22e-2)" "potential prognostic favorable (2.68e-4)" "unprognostic (1.44e-1)" "unprognostic (8.98e-2)" "unprognostic (3.56e-1)" "unprognostic (1.56e-1)" "unprognostic (2.22e-1)" "unprognostic (2.53e-1)" "unprognostic (1.92e-2)" "unprognostic (8.81e-2)" "unprognostic (2.22e-1)" "unprognostic (1.86e-1)" MUSK ENSG00000030304 "Muscle associated receptor tyrosine kinase" O15146 9 110668779-110806558 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Differentiation "Developmental protein, Kinase, Muscle protein, Receptor, Transferase, Tyrosine-protein kinase" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 2.7;skeletal muscle: 3.8" "Cell type enhanced" "Detected in many" "Ependymal cells: 194.2;Epicardial cells: 429.8;Fibro-adipogenic progenitors: 160.0;Leydig cells: 140.8;Myonuclei: 92.4;Myosatellite cells: 617.9;Peritubular myoid cells: 183.2;Thymic myoid cells: 386.1" "Cell type enriched" "Detected in many" 4 "ependymal cell: 245.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 8 "Sarcoma: 4.4" "Adrenal gland - Fibroblasts, Liver - Hepatic stellate cells" "Region enhanced" "Detected in some" "basal ganglia: 5.0" "Low region specificity" "Detected in some" NA NA "Cluster 52: Non-specific - Cellular respiration" "Cluster 46: Brainstem - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 9 "unprognostic (1.69e-2)" "unprognostic (4.93e-2)" MUSTN1 Mustang ENSG00000272573 "Musculoskeletal, embryonic nuclear protein 1" Q8IVN3 3 52833114-52835019 "Predicted intracellular proteins" "Chondrogenesis, Myogenesis" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 6 "blood vessel: 1491.2;skeletal muscle: 1710.5" "Group enriched" "Detected in some" 4 "Pericytes: 13.7;Vascular smooth muscle cells: 25.1" "Group enriched" "Detected in some" 32 "pericyte: 410.9;vascular associated smooth muscle cell: 399.6" "Cancer enhanced" "Detected in all" "Head and Neck Squamous Cell Carcinoma (TCGA): 44.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "Sarcoma: 13.6" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Heart muscle - Smooth muscle cells, Lung - Smooth muscle cells, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in all" NA NA 88000 "Cluster 35: Neutrophils - Protein binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 22: Non-specific - Basic cellular functions" "unprognostic (5.77e-2)" "unprognostic (2.56e-1)" "unprognostic (2.50e-2)" "unprognostic (4.07e-3)" "unprognostic (3.53e-3)" "unprognostic (1.46e-1)" "unprognostic (1.97e-1)" "unprognostic (1.94e-2)" "unprognostic (1.46e-1)" "unprognostic (3.43e-1)" "unprognostic (2.02e-3)" "unprognostic (1.55e-2)" "unprognostic (1.04e-1)" "unprognostic (8.62e-2)" "unprognostic (1.02e-3)" "unprognostic (1.74e-1)" "unprognostic (1.73e-1)" "unprognostic (4.70e-1)" "unprognostic (1.09e-1)" "unprognostic (1.20e-1)" "potential prognostic favorable (7.48e-4)" "unprognostic (1.25e-2)" "unprognostic (1.04e-1)" "unprognostic (3.23e-2)" "unprognostic (3.54e-3)" "unprognostic (6.03e-2)" "unprognostic (6.56e-2)" "unprognostic (4.97e-2)" MUTYH MYH ENSG00000132781 "MutY DNA glycosylase" Q9UIF7 1 45329163-45340893 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "Glycosidase, Hydrolase" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 7.4;Distal convoluted tubule cells: 7.6;Enteric stem cells: 8.4;Enteric transient amplifying cells: 7.8;Epididymal efferent duct absorptive cells: 6.4;Foveolar cells: 9.2;Goblet cells: 8.0;Loop of henle epithelial cells: 8.5;Megakaryocytes: 6.2;Papillary tip epithelial cells: 6.7;Podocytes: 7.7;Proximal tubule cells: 10.1;Renal collecting duct intercalated cells: 7.8;Renal collecting duct principal cells: 7.8;Renal connecting tubule cells: 7.9" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA008732 Uncertain Supported Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 64: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 15: Non-specific - Protein processing" 10 Nucleoplasm "HPA008732: " "unprognostic (1.41e-1)" "unprognostic (2.24e-1)" "unprognostic (8.63e-2)" "unprognostic (4.99e-3)" "unprognostic (9.07e-2)" "unprognostic (1.25e-1)" "unprognostic (1.64e-1)" "unprognostic (9.16e-3)" "unprognostic (6.56e-2)" "unprognostic (1.40e-1)" "unprognostic (7.43e-3)" "unprognostic (2.28e-1)" "unprognostic (1.40e-1)" "potential prognostic unfavorable (9.20e-8)" "unprognostic (6.37e-2)" "unprognostic (3.43e-2)" "unprognostic (5.91e-2)" "unprognostic (7.27e-2)" "unprognostic (2.39e-1)" "unprognostic (9.19e-2)" "unprognostic (7.69e-3)" "unprognostic (2.57e-1)" "unprognostic (1.15e-1)" "unprognostic (1.33e-1)" "unprognostic (3.07e-2)" "unprognostic (8.78e-2)" "unprognostic (9.14e-3)" "unprognostic (1.05e-3)" "unprognostic (2.61e-1)" "unprognostic (1.57e-2)" "unprognostic (2.59e-3)" MVB12A "FAM125A, FLJ32495" ENSG00000141971 "Multivesicular body subunit 12A" Q96EY5 19 17405722-17433724 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 241.9;Esophageal suprabasal cells: 165.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041885, HPA042231" Approved Supported Vesicles NA No "Cluster 10: Non-specific - Membrane trafficking" "Cluster 54: Non-specific - Ribosome" "Cluster 27: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 15: Non-specific - Protein processing" 27 Vesicles "HPA041885: , HPA042231: " "unprognostic (2.43e-1)" "unprognostic (4.71e-2)" "unprognostic (1.44e-1)" "unprognostic (1.99e-1)" "unprognostic (2.85e-1)" "unprognostic (2.37e-1)" "unprognostic (2.54e-1)" "unprognostic (4.93e-3)" "unprognostic (1.64e-1)" "potential prognostic favorable (6.20e-6)" "unprognostic (1.32e-1)" "unprognostic (1.56e-1)" "unprognostic (2.83e-3)" "unprognostic (6.55e-2)" "unprognostic (3.51e-1)" "unprognostic (4.06e-2)" "unprognostic (4.88e-2)" "unprognostic (1.65e-1)" "unprognostic (1.02e-1)" "unprognostic (3.01e-2)" "unprognostic (3.35e-1)" "unprognostic (3.77e-2)" "unprognostic (2.74e-1)" "unprognostic (4.35e-2)" "unprognostic (2.82e-1)" "unprognostic (1.68e-1)" "unprognostic (3.16e-2)" "unprognostic (1.18e-2)" "unprognostic (8.81e-2)" MVB12B "C9orf28, FAM125B, FLJ00001" ENSG00000196814 "Multivesicular body subunit 12B" Q9H7P6 9 126326829-126507041 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "brain: 110.8" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 437.9;Ependymal cells: 226.1;Microglia: 261.9;Oligodendrocytes: 603.4;Renal collecting duct intercalated cells: 265.4" "Cell type enhanced" "Detected in all" "oligodendrocyte: 976.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 2.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Endothelial cells, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043683 Supported "Vesicles,Primary cilium,Primary cilium tip,Primary cilium transition zone" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 59: Leukemia - T-cell receptor" "Cluster 80: Oligodendrocytes - Myelination" 6 Vesicles "Primary cilium, Primary cilium tip, Primary cilium transition zone" "HPA043683: " "unprognostic (1.71e-2)" "unprognostic (1.75e-1)" "unprognostic (6.31e-2)" "unprognostic (1.82e-1)" "unprognostic (2.26e-3)" "unprognostic (8.07e-2)" "unprognostic (3.99e-3)" "unprognostic (1.57e-1)" "unprognostic (3.77e-1)" "unprognostic (2.11e-3)" "unprognostic (7.49e-2)" "unprognostic (1.21e-1)" "unprognostic (1.68e-2)" "unprognostic (1.02e-3)" "unprognostic (2.53e-1)" "unprognostic (8.18e-2)" "potential prognostic favorable (4.80e-4)" "unprognostic (5.26e-2)" "unprognostic (4.36e-1)" "unprognostic (1.14e-3)" "unprognostic (7.46e-3)" "unprognostic (1.96e-1)" "unprognostic (1.04e-2)" "unprognostic (1.60e-3)" "unprognostic (1.07e-1)" "unprognostic (6.85e-2)" "unprognostic (1.45e-1)" "unprognostic (2.55e-1)" "unprognostic (1.68e-1)" MVD MPD ENSG00000167508 "Mevalonate diphosphate decarboxylase" P53602 16 88651935-88663161 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Lyase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 140.8;Colonocytes: 140.3;Epididymal principal cells: 349.7;Esophageal apical cells: 229.3;Esophageal suprabasal cells: 214.0;Late spermatids: 165.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary gland basal cells, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041404, HPA048250" Uncertain Approved "Cell Junctions,Cytosol" NA NA 250000 "Cluster 13: Non-specific - Mitochondria" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 8 Cytosol "Cell Junctions" "HPA041404: , HPA048250: " "unprognostic (2.47e-2)" "unprognostic (8.92e-2)" "unprognostic (4.32e-2)" "unprognostic (7.23e-2)" "unprognostic (2.62e-1)" "unprognostic (1.94e-1)" "unprognostic (1.39e-1)" "unprognostic (3.28e-2)" "unprognostic (5.47e-2)" "unprognostic (1.91e-2)" "unprognostic (2.47e-2)" "unprognostic (1.63e-1)" "unprognostic (1.70e-3)" "unprognostic (1.45e-3)" "unprognostic (6.70e-3)" "unprognostic (1.10e-2)" "unprognostic (2.17e-1)" "unprognostic (1.01e-1)" "unprognostic (7.11e-2)" "unprognostic (3.47e-2)" "unprognostic (1.74e-1)" "unprognostic (2.01e-1)" "unprognostic (3.31e-2)" "unprognostic (4.26e-2)" "unprognostic (2.38e-1)" "unprognostic (2.72e-1)" "unprognostic (7.38e-2)" "unprognostic (1.94e-2)" "unprognostic (5.63e-2)" "unprognostic (1.21e-1)" "unprognostic (1.39e-1)" MVK "LRBP, MK" ENSG00000110921 "Mevalonate kinase" Q03426 12 109573255-109598125 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "Kinase, Transferase" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 58.8" "Cell type enhanced" "Detected in many" "Breast lactating cells: 74.8;Cardiomyocytes: 72.6;Early spermatids: 83.9;Esophageal apical cells: 202.5;Esophageal suprabasal cells: 79.1;Late primary spermatocytes: 68.3;Retinal horizontal cells: 74.1;Syncytiotrophoblasts: 71.4" "Cell type enhanced" "Detected in all" "lower rhombic lip: 41.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary gland basal cells, Pituitary gland - Corticotropes, Prostate - Prostate glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016961, HPA044110" Approved Supported Vesicles,Cytosol NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 49: Hindbrain - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 11 "Vesicles, Cytosol" "HPA016961: , HPA044110: " "unprognostic (8.51e-2)" "unprognostic (3.99e-2)" "unprognostic (1.61e-2)" "unprognostic (1.76e-2)" "unprognostic (3.06e-2)" "unprognostic (1.69e-1)" "unprognostic (1.37e-2)" "unprognostic (2.48e-3)" "unprognostic (1.50e-1)" "unprognostic (3.62e-2)" "unprognostic (3.91e-3)" "unprognostic (4.27e-2)" "unprognostic (2.35e-2)" "unprognostic (2.97e-2)" "unprognostic (2.98e-1)" "unprognostic (4.66e-1)" "unprognostic (5.69e-2)" "unprognostic (2.44e-1)" "unprognostic (4.01e-1)" "unprognostic (7.68e-2)" "unprognostic (9.08e-2)" "unprognostic (7.78e-2)" "unprognostic (1.90e-1)" "unprognostic (4.50e-2)" "unprognostic (9.32e-2)" "unprognostic (1.13e-1)" "unprognostic (1.79e-1)" "unprognostic (2.52e-1)" "unprognostic (3.43e-1)" "unprognostic (1.99e-1)" "unprognostic (2.24e-1)" MVP "LRP, VAULT1" ENSG00000013364 "Major vault protein" Q14764 16 29820394-29848039 "Cancer-related genes, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" Ribonucleoprotein "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 247.3;Colonocytes: 467.3;Enterocytes: 507.6;Syncytiotrophoblasts: 391.2" "Cell type enhanced" "Detected in all" "endothelial cell: 58.8;fibroblast: 46.9;leukocyte: 46.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002321, CAB002752, CAB022717, HPA064740" Enhanced Enhanced Cytosol NA NA 280000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 77: Intestine - Digestion" "Cluster 6: Non-specific - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 15 Cytosol "CAB002752: , CAB022717: , HPA002321: , HPA064740: " "unprognostic (7.64e-2)" "unprognostic (2.41e-2)" "unprognostic (1.73e-1)" "unprognostic (4.28e-2)" "unprognostic (1.24e-1)" "unprognostic (1.87e-1)" "unprognostic (2.56e-1)" "unprognostic (1.10e-1)" "unprognostic (8.70e-3)" "unprognostic (8.14e-2)" "potential prognostic favorable (9.55e-7)" "unprognostic (1.92e-1)" "potential prognostic favorable (4.01e-4)" "unprognostic (6.00e-3)" "unprognostic (8.88e-2)" "unprognostic (8.36e-2)" "unprognostic (3.85e-2)" "unprognostic (1.03e-2)" "unprognostic (7.33e-2)" "unprognostic (1.21e-1)" "unprognostic (2.05e-2)" "unprognostic (1.21e-2)" "unprognostic (3.03e-1)" "unprognostic (1.40e-1)" "unprognostic (3.93e-1)" "unprognostic (2.34e-1)" "unprognostic (2.35e-3)" "unprognostic (1.97e-1)" "unprognostic (1.31e-2)" "unprognostic (1.05e-2)" "unprognostic (7.60e-2)" MX1 "IFI-78K, lncMX1-215, MxA" ENSG00000157601 "MX dynamin like GTPase 1" P20591 21 41420020-41470071 "Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 119.6" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 132.5;pDCs: 137.6" "Cell type enhanced" "Detected in all" "endothelial cell: 174.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA030917, HPA030918, HPA049724" Approved Approved Supported "Nuclear membrane,Cytosol" No NA "Cluster 13: Non-specific - Mitochondria" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 18 "Nuclear membrane, Cytosol" "HPA030917: , HPA030918: , HPA049724: " "unprognostic (3.23e-1)" "unprognostic (1.66e-1)" "unprognostic (2.00e-1)" "unprognostic (1.06e-1)" "unprognostic (7.01e-2)" "unprognostic (4.88e-2)" "unprognostic (2.57e-1)" "unprognostic (4.33e-2)" "unprognostic (7.64e-2)" "unprognostic (1.09e-1)" "unprognostic (4.54e-3)" "unprognostic (4.83e-2)" "unprognostic (1.47e-2)" "unprognostic (3.57e-2)" "unprognostic (2.68e-2)" "unprognostic (2.90e-2)" "unprognostic (1.12e-2)" "unprognostic (5.11e-2)" "unprognostic (2.60e-1)" "unprognostic (4.49e-1)" "unprognostic (1.80e-2)" "unprognostic (4.50e-3)" "unprognostic (3.30e-2)" "unprognostic (3.94e-1)" "unprognostic (2.77e-1)" "unprognostic (4.81e-3)" "unprognostic (2.63e-1)" "unprognostic (8.69e-2)" "unprognostic (1.80e-1)" "unprognostic (3.39e-1)" "unprognostic (5.48e-2)" MX2 MXB ENSG00000183486 "MX dynamin like GTPase 2" P20592 21 41361999-41409393 "Plasma proteins, Predicted intracellular proteins, Transporters" "Antiviral defense, Immunity, Innate immunity, mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 28.4" "Cell type enriched" "Detected in many" 4 "Neutrophils: 1075.4" "Group enriched" "Detected in many" 4 "central nervous system macrophage: 65.1;endothelial cell: 57.7;leukocyte: 60.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in all" 4 "neutrophil: 152.0" "Lineage enriched" "Detected in all" 4 "granulocytes: 152.0" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Lung - NK-cells (Lung), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" HPA030235 Uncertain NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 3 "HPA030235: " "unprognostic (6.46e-3)" "unprognostic (1.97e-1)" "unprognostic (1.44e-1)" "unprognostic (4.29e-2)" "unprognostic (1.31e-1)" "unprognostic (1.46e-1)" "unprognostic (5.58e-2)" "unprognostic (2.72e-1)" "unprognostic (2.96e-1)" "unprognostic (1.75e-1)" "unprognostic (1.70e-3)" "unprognostic (3.37e-2)" "potential prognostic unfavorable (3.57e-6)" "unprognostic (2.57e-2)" "unprognostic (2.03e-1)" "unprognostic (1.32e-1)" "unprognostic (5.96e-2)" "unprognostic (1.33e-1)" "unprognostic (1.93e-1)" "unprognostic (1.17e-1)" "unprognostic (3.95e-1)" "unprognostic (1.37e-3)" "unprognostic (1.36e-2)" "unprognostic (4.49e-1)" "unprognostic (2.28e-1)" "unprognostic (2.24e-2)" "unprognostic (3.24e-1)" "unprognostic (5.89e-2)" "unprognostic (2.26e-2)" "unprognostic (3.49e-1)" "unprognostic (3.94e-2)" MXD1 "bHLHc58, MAD, MAD1" ENSG00000059728 "MAX dimerization protein 1" Q05195 2 69897688-69942945 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 163.8;esophagus: 125.8" "Group enriched" "Detected in many" 7 "Esophageal apical cells: 5212.2;Neutrophils: 4650.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "neutrophil: 498.7" "Lineage enriched" "Detected in all" 49 "granulocytes: 498.7" "Low cancer specificity" "Detected in all" "Liver - Neutrophils, Spleen - Neutrophils_2, Stomach - Gastric mucous cells, Testis - Early spermatids, Thyroid gland - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001599 Enhanced Uncertain Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 16: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 9 "Nucleoplasm, Mitochondria" Cytosol "HPA001599: " "unprognostic (3.80e-1)" "unprognostic (2.31e-1)" "unprognostic (2.90e-1)" "unprognostic (1.17e-1)" "unprognostic (2.72e-3)" "unprognostic (1.03e-2)" "unprognostic (3.55e-1)" "unprognostic (6.31e-2)" "unprognostic (2.81e-1)" "unprognostic (1.91e-1)" "unprognostic (6.76e-3)" "unprognostic (2.05e-1)" "unprognostic (4.83e-2)" "unprognostic (2.14e-2)" "unprognostic (4.26e-3)" "unprognostic (1.18e-2)" "unprognostic (3.21e-2)" "unprognostic (9.08e-2)" "unprognostic (4.70e-2)" "unprognostic (8.15e-2)" "unprognostic (6.58e-2)" "potential prognostic unfavorable (7.42e-4)" "unprognostic (8.01e-3)" "unprognostic (7.16e-2)" "unprognostic (5.95e-2)" "unprognostic (5.45e-2)" "unprognostic (1.05e-1)" "unprognostic (2.31e-1)" "unprognostic (8.91e-2)" "unprognostic (2.91e-3)" "unprognostic (2.93e-2)" MXD3 "bHLHc13, MAD3" ENSG00000213347 "MAX dimerization protein 3" Q9BW11 5 177301461-177312757 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 38.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 47.9;Enteric transient amplifying cells: 37.4;Epicardial cells: 86.4;Neutrophil progenitors: 46.2;Neutrophils: 76.3;Paneth cells: 34.8;Plasma cells: 46.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 20.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Neutrophils_2" "Group enriched" "Detected in many" 5 "amygdala: 1.8;basal ganglia: 2.1;cerebral cortex: 1.1;hippocampal formation: 1.0;white matter: 2.4" "Low region specificity" "Detected in all" HPA070111 Approved Nucleoplasm,Nucleoli NA Yes "Cluster 35: Neutrophils - Protein binding" "Cluster 15: Bone marrow - Innate immune response" "Cluster 6: Non-specific - Immune response" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Non-specific - Cell proliferation" 16 "Nucleoplasm, Nucleoli" "HPA070111: " "unprognostic (4.13e-2)" "unprognostic (1.60e-1)" "unprognostic (4.12e-1)" "unprognostic (2.72e-1)" "unprognostic (2.50e-1)" "unprognostic (9.12e-2)" "unprognostic (3.23e-1)" "unprognostic (4.17e-2)" "unprognostic (9.22e-3)" "unprognostic (2.10e-3)" "validated prognostic unfavorable (1.01e-13)" "validated prognostic unfavorable (2.11e-6)" "unprognostic (1.01e-2)" "potential prognostic unfavorable (1.13e-5)" "unprognostic (1.03e-3)" "unprognostic (1.87e-2)" "unprognostic (1.64e-1)" "unprognostic (2.26e-1)" "unprognostic (4.61e-2)" "unprognostic (9.23e-2)" "unprognostic (1.37e-2)" "unprognostic (7.29e-2)" "unprognostic (4.73e-2)" "unprognostic (4.06e-2)" "unprognostic (2.30e-1)" "unprognostic (6.48e-2)" "unprognostic (6.80e-2)" "unprognostic (1.20e-3)" "unprognostic (1.64e-1)" "unprognostic (1.66e-1)" "unprognostic (3.05e-1)" MXD4 "bHLHc12, MAD4, MST149, MSTP149" ENSG00000123933 "MAX dimerization protein 4" Q14582 4 2247432-2262109 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053363 Supported Cytosol NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 7 Cytosol "HPA053363: " "unprognostic (1.33e-2)" "unprognostic (2.27e-1)" "unprognostic (9.01e-2)" "unprognostic (4.36e-2)" "unprognostic (1.87e-1)" "unprognostic (3.63e-1)" "unprognostic (2.12e-1)" "potential prognostic favorable (4.39e-5)" "potential prognostic favorable (4.29e-4)" "unprognostic (3.15e-1)" "potential prognostic favorable (7.12e-4)" "unprognostic (7.92e-2)" "potential prognostic favorable (8.27e-4)" "unprognostic (2.83e-1)" "unprognostic (2.99e-2)" "unprognostic (2.74e-2)" "unprognostic (3.80e-1)" "unprognostic (7.26e-2)" "unprognostic (2.26e-1)" "unprognostic (1.94e-1)" "unprognostic (5.93e-2)" "potential prognostic favorable (2.71e-4)" "unprognostic (1.88e-1)" "unprognostic (1.13e-1)" "unprognostic (1.58e-1)" "unprognostic (3.88e-2)" "unprognostic (3.53e-1)" "unprognostic (1.04e-1)" "unprognostic (1.33e-1)" "unprognostic (2.51e-1)" "potential prognostic favorable (6.66e-4)" MXI1 "bHLHc11, MAD2, MXD2, MXI" ENSG00000119950 "MAX interactor 1, dimerization protein" P50539 10 110207605-110287365 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocytes: 303.8;Esophageal apical cells: 317.3;Melanocytes: 341.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035319, HPA035320, HPA056762" Approved Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" Yes No "Cluster 43: Non-specific - Transcription & Translation" "Cluster 73: Brain - Neuronal signaling" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 13 Nucleoplasm "Nucleoli, Nucleoli rim, Cytosol" "HPA035319: , HPA035320: , HPA056762: " "unprognostic (4.98e-1)" "potential prognostic unfavorable (4.48e-4)" "unprognostic (2.64e-1)" "unprognostic (5.18e-2)" "unprognostic (7.11e-2)" "unprognostic (9.31e-2)" "unprognostic (1.38e-1)" "unprognostic (1.58e-2)" "unprognostic (2.77e-2)" "unprognostic (9.84e-3)" "potential prognostic favorable (2.69e-7)" "unprognostic (1.82e-2)" "unprognostic (6.77e-2)" "unprognostic (2.80e-2)" "unprognostic (4.49e-2)" "unprognostic (3.79e-1)" "unprognostic (4.55e-3)" "unprognostic (1.65e-1)" "unprognostic (4.25e-2)" "unprognostic (1.03e-1)" "potential prognostic unfavorable (7.74e-4)" "unprognostic (5.50e-3)" "unprognostic (7.63e-2)" "unprognostic (8.61e-3)" "unprognostic (7.33e-3)" "unprognostic (2.47e-1)" "unprognostic (3.22e-1)" "unprognostic (1.49e-1)" "unprognostic (5.32e-2)" "unprognostic (4.22e-1)" "unprognostic (1.04e-1)" MXRA5 DKFZp564I1922 ENSG00000101825 "Matrix remodeling associated 5" Q9NR99 X 3308565-3346652 "Cancer-related genes, Disease related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 32.8" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 40.6;Basal keratinocytes: 26.2;Endometrial secretory cells: 37.6;Epididymal basal cells: 23.8;Fibroblasts: 43.1;Gastric progenitor cells: 25.6;Pancreatic acinar cells: 178.2;Papillary tip epithelial cells: 52.2;Renal collecting duct principal cells: 68.3;Renal connecting tubule cells: 32.7;Salivary basal cells: 33.9;Salivary myoepithelial cells: 26.5" "Group enriched" "Detected in some" 5 "fibroblast: 49.9;pericyte: 34.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "thyroid cancer: 42.4" "Adrenal gland - Adrenal cortex cells, Liver - Hepatic stellate cells, Minor Salivary Gland - Fibroblasts, Skin - Fibroblasts_1" "HPA000508, HPA076518" Uncertain Uncertain Mitochondria "Secreted to extracellular matrix" "No annotated function" NA NA 1800000 "Cluster 58: Skin - Keratinization" "Cluster 12: Non-specific - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" Mitochondria "HPA000508: , HPA076518: " "unprognostic (6.46e-2)" "unprognostic (2.42e-1)" "unprognostic (1.14e-1)" "unprognostic (2.57e-2)" "unprognostic (1.24e-1)" "unprognostic (1.22e-1)" "unprognostic (1.86e-3)" "unprognostic (3.67e-2)" "unprognostic (1.41e-1)" "unprognostic (1.20e-1)" "unprognostic (1.67e-1)" "unprognostic (1.64e-1)" "unprognostic (2.07e-1)" "unprognostic (8.72e-2)" "unprognostic (8.16e-3)" "unprognostic (1.28e-2)" "unprognostic (1.87e-3)" "unprognostic (1.32e-1)" "unprognostic (1.79e-1)" "unprognostic (3.46e-2)" "unprognostic (8.75e-2)" "unprognostic (5.79e-3)" "unprognostic (1.52e-1)" "unprognostic (1.84e-1)" "unprognostic (3.47e-1)" "unprognostic (1.17e-3)" "unprognostic (2.61e-2)" "unprognostic (1.89e-1)" "unprognostic (2.27e-2)" "unprognostic (1.11e-1)" "unprognostic (2.89e-1)" MXRA7 "FLJ46603, PS1TP1, TMAP1" ENSG00000182534 "Matrix remodeling associated 7" P84157 17 76672551-76711004 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Müller glia: 181.0;Pancreatic islet cells: 120.9;Rod photoreceptor cells: 125.8;Smooth muscle cells: 172.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Thyroid gland - Thyroid glandular cells" "HPA044819, HPA075316" Uncertain Enhanced "Endoplasmic reticulum" NA NA 45000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 44: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 62: Smooth muscle cells - Muscle contraction" 5 "Endoplasmic reticulum" "HPA044819: , HPA075316: " "unprognostic (3.19e-1)" "unprognostic (1.90e-1)" "unprognostic (2.40e-1)" "unprognostic (1.67e-1)" "unprognostic (1.50e-1)" "unprognostic (2.67e-3)" "unprognostic (2.99e-2)" "potential prognostic unfavorable (8.93e-5)" "unprognostic (5.16e-2)" "unprognostic (1.59e-2)" "unprognostic (1.95e-3)" "unprognostic (7.23e-2)" "unprognostic (6.31e-2)" "unprognostic (2.16e-3)" "unprognostic (1.27e-1)" "potential prognostic favorable (3.55e-4)" "unprognostic (3.33e-2)" "unprognostic (1.40e-1)" "unprognostic (1.21e-1)" "unprognostic (2.06e-2)" "unprognostic (1.58e-3)" "unprognostic (2.17e-3)" "unprognostic (3.18e-1)" "unprognostic (1.23e-1)" "unprognostic (1.54e-1)" "unprognostic (2.24e-3)" "unprognostic (1.57e-1)" "unprognostic (3.86e-2)" "unprognostic (1.58e-1)" "unprognostic (1.04e-2)" "unprognostic (2.75e-1)" MXRA8 DKFZp586E2023 ENSG00000162576 "Matrix remodeling associated 8" Q9BRK3 1 1352689-1361777 "Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 116.2;Decidual stromal cells: 284.5;Endometrial stromal cells: 112.7;Extravillous trophoblasts: 380.4;Fibro-adipogenic progenitors: 68.1;Fibroblasts: 200.3;Hepatic stellate cells: 96.8;Leydig cells: 163.7;Ovarian stromal cells: 111.1;Peritubular myoid cells: 176.2;Podocytes: 105.0" "Cell type enhanced" "Detected in many" "fibroblast: 128.9;pericyte: 117.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "naive CD8 T-cell: 6.4" "Lineage enriched" "Detected in single" 64 "T-cells: 6.4" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Fibroblasts, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053958, HPA055780" Uncertain Approved Nucleoli NA NA 530000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 74: Non-specific - Signal transduction" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 5 Nucleoli "HPA053958: , HPA055780: " "unprognostic (4.60e-3)" "unprognostic (1.25e-1)" "unprognostic (4.78e-2)" "unprognostic (1.25e-3)" "unprognostic (9.98e-3)" "unprognostic (9.94e-2)" "unprognostic (1.06e-3)" "unprognostic (2.97e-3)" "unprognostic (1.33e-1)" "unprognostic (1.43e-1)" "potential prognostic unfavorable (1.14e-4)" "unprognostic (4.41e-2)" "unprognostic (1.08e-1)" "unprognostic (5.54e-2)" "unprognostic (1.56e-3)" "unprognostic (2.09e-2)" "unprognostic (1.90e-3)" "unprognostic (2.22e-2)" "unprognostic (1.23e-1)" "unprognostic (8.79e-3)" "unprognostic (1.26e-1)" "unprognostic (4.53e-2)" "unprognostic (2.74e-2)" "unprognostic (3.47e-2)" "unprognostic (2.00e-1)" "unprognostic (2.53e-3)" "unprognostic (2.02e-1)" "unprognostic (1.26e-3)" "unprognostic (4.68e-2)" "unprognostic (2.83e-1)" "unprognostic (4.42e-3)" MYADM ENSG00000179820 "Myeloid associated differentiation marker" Q96S97 19 53864763-53876435 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 313.7;Extravillous trophoblasts: 363.7;Fallopian secretory cells: 385.2;Hepatic stellate cells: 361.5;Mast cells: 426.8;Neutrophils: 530.5;Smooth muscle cells: 318.2" "Cell type enhanced" "Detected in many" "vascular associated smooth muscle cell: 79.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 208.2" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Colon - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Fibroblasts, Skin - Fibroblasts_2, Testis - Spermatocytes, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056301 Approved "Nuclear speckles" NA NA 49000 "Cluster 21: Neutrophils - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 14: Neurons - Synaptic function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 39 "Nuclear speckles" "HPA056301: " "unprognostic (6.09e-2)" "unprognostic (4.82e-2)" "unprognostic (6.71e-3)" "unprognostic (3.89e-2)" "unprognostic (2.82e-1)" "unprognostic (5.62e-2)" "unprognostic (2.60e-2)" "potential prognostic unfavorable (2.46e-5)" "unprognostic (5.22e-3)" "unprognostic (2.09e-2)" "unprognostic (1.34e-3)" "unprognostic (1.62e-2)" "unprognostic (1.72e-1)" "unprognostic (5.24e-3)" "unprognostic (1.63e-2)" "unprognostic (6.55e-2)" "unprognostic (5.78e-3)" "potential prognostic unfavorable (1.91e-4)" "unprognostic (9.43e-3)" "unprognostic (1.79e-2)" "unprognostic (1.10e-1)" "unprognostic (2.50e-1)" "unprognostic (9.96e-2)" "unprognostic (3.64e-1)" "unprognostic (9.26e-2)" "unprognostic (1.88e-2)" "unprognostic (9.45e-2)" "unprognostic (1.68e-3)" "unprognostic (4.67e-1)" "unprognostic (1.62e-2)" "unprognostic (1.17e-1)" MYADML2 LOC255275 ENSG00000185105 "Myeloid associated differentiation marker like 2" A6NDP7 17 81939645-81947233 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "skeletal muscle: 78.7" "Cell type enriched" "Detected in some" 6 "Cardiomyocytes: 33.5" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Colon Adenocarcinoma (TCGA): 1.6;Rectum Adenocarcinoma (TCGA): 2.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 14 "lymphoma: 8.0" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041856, HPA048476" Uncertain NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 10 "HPA041856: , HPA048476: " "unprognostic (2.84e-2)" "unprognostic (4.05e-1)" "unprognostic (1.74e-1)" MYB c-myb ENSG00000118513 "MYB proto-oncogene, transcription factor" P10242 6 135181308-135219173 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 33.1;breast: 18.9;intestine: 24.9;lymphoid tissue: 61.5" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 107.8;Enteric stem cells: 83.8;Erythrocyte progenitors: 174.9;Fallopian tube ciliated cells: 79.1;Hematopoietic stem cells: 280.5;Mast cells: 70.4;Megakaryocyte progenitors: 102.3;Megakaryocyte-Erythroid progenitors: 314.5;Monocyte progenitors: 100.0;Neutrophil progenitors: 215.4;Respiratory ciliated cells: 124.6;Respiratory deuterosomal cells: 157.6;Thymocytes: 90.6" "Group enriched" "Detected in many" 7 "ependymal cell: 54.4;LAMP5-LHX6 and Chandelier: 49.1;medium spiny neuron: 30.6" "Group enriched" "Detected in many" 4 "Breast Invasive Carcinoma (TCGA): 37.9;Colon Adenocarcinoma (TCGA): 32.5;Rectum Adenocarcinoma (TCGA): 35.7;Stomach Adenocarcinoma (TCGA): 13.1" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "basophil: 4.5;eosinophil: 5.3;plasmacytoid DC: 1.5" "Group enriched" "Detected in many" 5 "dendritic cells: 1.5;granulocytes: 5.3" "Cancer enhanced" "Detected in many" "Leukemia: 175.7;lymphoma: 55.4" "Adipose subcutaneous - Mast cells, Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Stomach - Mitotic cells (Stomach), Thyroid gland - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB017704, HPA071605" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 41: Basophils - Unknown function" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 33: Neurons - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 26 Nucleoplasm Cytosol "CAB017704: , HPA071605: " "unprognostic (2.06e-1)" "unprognostic (5.37e-1)" "unprognostic (5.41e-2)" "unprognostic (6.34e-2)" "unprognostic (1.87e-1)" "unprognostic (2.45e-3)" "unprognostic (1.05e-2)" "unprognostic (1.18e-2)" "unprognostic (1.80e-1)" "unprognostic (2.00e-3)" "unprognostic (9.39e-2)" "unprognostic (3.30e-2)" "unprognostic (1.99e-1)" "unprognostic (4.65e-2)" "unprognostic (7.13e-2)" "unprognostic (9.47e-2)" "unprognostic (1.19e-3)" "unprognostic (2.12e-2)" "unprognostic (1.22e-1)" "unprognostic (6.15e-3)" "unprognostic (6.13e-2)" "unprognostic (1.77e-1)" MYBBP1A "FLJ37886, P160, PAP2, Pol5" ENSG00000132382 "MYB binding protein 1a" Q9BQG0 17 4538897-4555386 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Ribosome biogenesis, Transcription, Transcription regulation" "Activator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005466 Supported Supported Nucleoli,Vesicles No No 49000 "Cluster 30: Non-specific - DNA binding" "Cluster 24: Non-specific - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 84 Nucleoli Vesicles "HPA005466: " "unprognostic (5.60e-2)" "unprognostic (1.10e-1)" "unprognostic (2.97e-1)" "potential prognostic unfavorable (1.46e-4)" "unprognostic (3.88e-1)" "unprognostic (4.59e-2)" "unprognostic (1.06e-1)" "unprognostic (9.71e-3)" "unprognostic (2.28e-1)" "unprognostic (6.08e-2)" "unprognostic (8.19e-2)" "unprognostic (3.02e-1)" "unprognostic (3.51e-1)" "unprognostic (6.01e-2)" "unprognostic (1.52e-2)" "unprognostic (3.38e-2)" "unprognostic (1.87e-2)" "unprognostic (6.37e-2)" "unprognostic (1.03e-1)" "unprognostic (9.03e-3)" "unprognostic (1.07e-2)" "unprognostic (1.05e-1)" "unprognostic (1.27e-2)" "potential prognostic unfavorable (8.50e-4)" "unprognostic (8.17e-2)" "unprognostic (3.29e-2)" "unprognostic (1.75e-2)" "unprognostic (6.28e-2)" "unprognostic (2.62e-1)" "unprognostic (8.87e-3)" "unprognostic (1.50e-2)" MYBL1 "A-myb, AMYB" ENSG00000185697 "MYB proto-oncogene like 1" P10243 8 66562175-66614247 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 18.8;testis: 11.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 61.9;Early primary spermatocytes: 49.4;Innate lymphoid cells: 57.5;NK-cells: 260.0;T-cells: 171.1" "Cell type enriched" "Detected in many" 19 "leukocyte: 367.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 1.9;MAIT T-cell: 1.3" "Lineage enhanced" "Detected in single" "T-cells: 1.9" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 123.9" "Adipose visceral - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Skeletal muscle - Fibroblasts, Testis - Early spermatids, Testis - Spermatocytes, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA008791 Uncertain Supported Nucleoplasm NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 8 Nucleoplasm "HPA008791: " "unprognostic (3.20e-1)" "unprognostic (2.57e-1)" "unprognostic (1.88e-1)" "unprognostic (3.46e-1)" "unprognostic (3.05e-1)" "unprognostic (1.69e-1)" "unprognostic (1.72e-1)" "unprognostic (3.18e-2)" "unprognostic (1.16e-1)" "unprognostic (5.79e-3)" "unprognostic (2.20e-3)" "unprognostic (1.43e-2)" "potential prognostic unfavorable (2.03e-5)" "unprognostic (4.75e-2)" "unprognostic (2.69e-1)" "unprognostic (2.22e-3)" "unprognostic (3.40e-2)" "unprognostic (1.78e-1)" "unprognostic (3.07e-1)" "unprognostic (8.42e-2)" "unprognostic (1.37e-3)" "unprognostic (1.91e-2)" "unprognostic (5.50e-2)" "unprognostic (2.16e-1)" "unprognostic (6.59e-2)" "unprognostic (1.84e-1)" "unprognostic (1.26e-1)" "unprognostic (1.13e-2)" MYBL2 "B-MYB, BMYB" ENSG00000101057 "MYB proto-oncogene like 2" P10244 20 43667019-43716495 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 86.6;lymphoid tissue: 51.8" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 54.5;Erythrocyte progenitors: 172.2;Extravillous trophoblasts: 38.4;Megakaryocyte progenitors: 62.3;Migrating cytotrophoblasts: 37.1;Monocyte progenitors: 65.8;Neutrophil progenitors: 44.9;pDCs: 123.2;Plasma cells: 117.9" "Low cell type specificity" "Detected in single" "Cancer enriched" "Detected in all" 5 "Testicular Germ Cell Tumor (TCGA): 478.7" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 34 "plasmacytoid DC: 91.7" "Lineage enriched" "Detected in many" 34 "dendritic cells: 91.7" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Thyroid gland - Mitotic cells (Thyroid)" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB017114, HPA030530, HPA055416" Uncertain Supported Nucleoplasm,Cytosol Yes Yes "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 62: Non-specific - Plasma proteins" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 35 Nucleoplasm Cytosol "CAB017114: , HPA030530: , HPA055416: " "unprognostic (1.53e-1)" "unprognostic (1.73e-2)" "unprognostic (1.35e-1)" "unprognostic (7.28e-2)" "unprognostic (1.76e-1)" "unprognostic (3.24e-2)" "unprognostic (1.70e-1)" "unprognostic (8.10e-2)" "unprognostic (2.31e-1)" "potential prognostic unfavorable (3.85e-6)" "validated prognostic unfavorable (2.06e-9)" "validated prognostic unfavorable (2.73e-6)" "potential prognostic unfavorable (9.83e-9)" "validated prognostic unfavorable (3.54e-9)" "validated prognostic unfavorable (9.59e-9)" "validated prognostic unfavorable (1.64e-5)" "validated prognostic unfavorable (7.37e-4)" "unprognostic (8.91e-2)" "unprognostic (7.00e-2)" "unprognostic (2.26e-1)" "unprognostic (1.07e-1)" "unprognostic (1.65e-3)" "unprognostic (5.02e-3)" "unprognostic (1.66e-2)" "unprognostic (1.08e-1)" "unprognostic (4.45e-2)" "unprognostic (7.46e-3)" "unprognostic (9.33e-2)" "unprognostic (1.16e-1)" "unprognostic (1.50e-1)" "unprognostic (1.31e-1)" MYBPC1 ssMyBP-C ENSG00000196091 "Myosin binding protein C1" Q00872 12 101568353-101686028 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell adhesion" "Actin-binding, Muscle protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 85 "skeletal muscle: 10574.4;tongue: 4864.3" "Group enriched" "Detected in many" 10 "Myonuclei: 14831.0;Thymic myoid cells: 5551.4" "Cell type enriched" "Detected in many" 6 "astrocyte: 136.3" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 94.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 28 "Gastric cancer: 6.1;prostate cancer: 9.0" "Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Prostate - Prostate glandular cells, Skeletal muscle - Skeletal myocytes, Skin - Eccrine sweat gland cells, Testis - Early spermatids, Testis - Late spermatids" "Group enriched" "Detected in many" 9 "cerebellum: 39.6;olfactory bulb: 10.6" "Low region specificity" "Detected in all" "HPA021004, HPA027614" Enhanced NA NA 210000 "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 19: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 55: Myocytes - Oxidative muscle function" 4 "HPA021004: , HPA027614: " "unprognostic (1.24e-1)" "potential prognostic favorable (1.60e-4)" "unprognostic (1.78e-1)" "unprognostic (4.75e-2)" "unprognostic (1.87e-2)" "unprognostic (1.29e-1)" "unprognostic (3.22e-2)" "unprognostic (1.61e-1)" "unprognostic (1.19e-1)" "unprognostic (7.18e-2)" "unprognostic (2.02e-1)" "unprognostic (2.84e-1)" "unprognostic (1.04e-1)" "unprognostic (9.52e-3)" "unprognostic (3.79e-2)" MYBPC2 "fsMyBP-C, MGC163408, MYBPCF" ENSG00000086967 "Myosin binding protein C2" Q14324 19 50432892-50466321 "Predicted intracellular proteins" "Cell adhesion" "Actin-binding, Muscle protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "skeletal muscle: 4065.8;tongue: 1120.1" "Group enriched" "Detected in some" 5 "Myonuclei: 280.6;Oocytes: 152.0;Thymic myoid cells: 112.8" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 12 "Head and Neck Squamous Cell Carcinoma (TCGA): 14.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "lymphoma: 28.4;Myeloma: 45.1" "Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA042991 Enhanced NA NA 190000 "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 49: Hindbrain - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 2 "HPA042991: " "unprognostic (4.59e-3)" "unprognostic (3.12e-1)" MYBPC3 "CMH4, cMyBP-C, FHC" ENSG00000134571 "Myosin binding protein C3" Q14896 11 47331406-47352702 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Actin-binding, Muscle protein" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 186 "heart muscle: 1615.9" "Cell type enriched" "Detected in some" 25 "Cardiomyocytes: 2429.8" "Cell type enhanced" "Detected in single" "central nervous system macrophage: 2.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Lung - Neutrophils_2, Spleen - Neutrophils_2, Testis - Late spermatids" "Region enriched" "Detected in some" 33 "cerebellum: 34.4" "Low region specificity" "Detected in all" "HPA040147, HPA043898" Enhanced NA NA 17000 "Cluster 35: Non-specific - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 18: Liver cancer - Metabolism" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 3 "HPA040147: , HPA043898: " MYBPH ENSG00000133055 "Myosin binding protein H" Q13203 1 203167811-203175826 "Predicted intracellular proteins" "Cell adhesion" "Muscle protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "salivary gland: 17.1;skeletal muscle: 72.9;tongue: 18.2" "Cell type enriched" "Detected in some" 58 "Thymic myoid cells: 392.9" "Cell type enhanced" "Detected in single" "central nervous system macrophage: 1.9" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 30.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "plasmacytoid DC: 2.5" "Lineage enriched" "Detected in single" 5 "dendritic cells: 2.5" "Cancer enhanced" "Detected in some" "Leukemia: 18.3;Sarcoma: 14.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA061383 Enhanced Approved Nucleoplasm,Nucleoli,Mitochondria NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 1 "Nucleoplasm, Nucleoli, Mitochondria" "HPA061383: " "unprognostic (5.38e-3)" "unprognostic (2.71e-2)" "unprognostic (3.96e-2)" "potential prognostic unfavorable (4.49e-4)" "unprognostic (4.57e-2)" "unprognostic (7.62e-2)" "unprognostic (1.17e-3)" "unprognostic (2.15e-1)" "unprognostic (3.23e-1)" "unprognostic (2.08e-2)" "unprognostic (1.43e-1)" MYBPHL ENSG00000221986 "Myosin binding protein H like" A2RUH7 1 109292365-109307011 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 36 "heart muscle: 101.4" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 4.4;Corticotrophs: 6.8;Mesothelial cells: 5.5;Myosatellite cells: 9.0;Oligodendrocytes: 3.5;Podocytes: 4.6;Rod photoreceptor cells: 18.3;Sertoli cells: 4.0" "Cell type enhanced" "Detected in many" "deep-layer near-projecting: 13.7;hippocampal CA1-3: 9.7;hippocampal CA4: 12.6" "Cancer enhanced" "Detected in some" "Lung Adenocarcinoma (TCGA): 3.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 8 "Sarcoma: 4.6" "Pituitary gland - Corticotropes" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA077633 Approved Vesicles NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 79: Photoreceptor cells - Phototransduction" 11 Vesicles "HPA077633: " "unprognostic (3.33e-2)" "potential prognostic favorable (3.38e-5)" "unprognostic (1.22e-1)" "unprognostic (2.45e-1)" "unprognostic (3.35e-2)" MYC "bHLHe39, c-Myc, MYCC" ENSG00000136997 "MYC proto-oncogene, bHLH transcription factor" P01106 8 127735434-127742951 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 250.6;skin 1: 277.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 745.2;Breast secretory cells: 398.2;Decidual stromal cells: 1088.5;Esophageal basal cells: 309.2;Megakaryocyte-Erythroid progenitors: 261.0;Pericytes: 282.6;Smooth muscle cells: 266.7;Suprabasal keratinocytes: 718.8" "Cell type enhanced" "Detected in many" "lower rhombic lip: 12.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000084, CAB010307, HPA055893, HPA066556" Approved Enhanced Nucleoplasm NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 58: Skin - Keratinization" "Cluster 49: Hindbrain - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 103: Non-specific - Basic cellular processes" 1427 Nucleoplasm "CAB000084: , CAB010307: , HPA055893: , HPA066556: " "unprognostic (3.45e-2)" "unprognostic (9.00e-2)" "unprognostic (1.21e-1)" "unprognostic (1.88e-2)" "unprognostic (1.31e-1)" "unprognostic (1.62e-1)" "unprognostic (5.86e-2)" "unprognostic (6.74e-3)" "unprognostic (1.02e-3)" "unprognostic (1.35e-1)" "unprognostic (3.51e-1)" "unprognostic (3.82e-1)" "unprognostic (6.10e-3)" "unprognostic (5.30e-2)" "potential prognostic unfavorable (4.83e-4)" "unprognostic (8.40e-3)" "potential prognostic unfavorable (4.02e-4)" "unprognostic (1.69e-1)" "unprognostic (1.91e-1)" "potential prognostic unfavorable (5.58e-4)" "unprognostic (2.04e-1)" "unprognostic (1.84e-3)" "unprognostic (6.37e-3)" "unprognostic (1.95e-3)" "potential prognostic favorable (1.57e-4)" "unprognostic (9.09e-3)" "unprognostic (2.59e-1)" "unprognostic (1.43e-1)" "unprognostic (2.35e-1)" "unprognostic (1.56e-1)" "unprognostic (4.20e-1)" MYCBP AMY-1 ENSG00000214114 "MYC binding protein" Q99417 1 38862493-38873368 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 51.4;Endometrial ciliated cells: 24.7;Fallopian tube ciliated cells: 32.4;Late primary spermatocytes: 17.2;Megakaryocytes: 24.7" "Cell type enhanced" "Detected in many" "ependymal cell: 11.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041188, HPA078331" Supported Approved Nucleoplasm,Mitochondria NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 107: Ciliated cells - Cilia assembly & function" 30 Nucleoplasm Mitochondria "HPA041188: , HPA078331: " "unprognostic (9.87e-2)" "unprognostic (3.79e-2)" "unprognostic (1.25e-1)" "unprognostic (2.41e-2)" "potential prognostic favorable (2.51e-4)" "unprognostic (1.25e-2)" "unprognostic (9.23e-2)" "unprognostic (1.65e-1)" "unprognostic (1.69e-2)" "potential prognostic unfavorable (8.10e-4)" "unprognostic (5.16e-2)" "unprognostic (3.21e-2)" "unprognostic (3.13e-1)" "potential prognostic unfavorable (1.73e-5)" "unprognostic (1.75e-3)" "unprognostic (3.90e-1)" "unprognostic (9.60e-2)" "unprognostic (3.49e-1)" "unprognostic (8.02e-2)" "unprognostic (1.35e-1)" "unprognostic (1.53e-2)" "unprognostic (3.12e-3)" "unprognostic (1.91e-1)" "unprognostic (4.81e-3)" "unprognostic (3.29e-2)" "unprognostic (8.79e-2)" "unprognostic (3.32e-2)" "unprognostic (2.59e-2)" "unprognostic (3.64e-1)" "unprognostic (1.36e-1)" "unprognostic (4.58e-1)" MYCBP2 "FLJ10106, KIAA0916, PAM, PHR1" ENSG00000005810 "MYC binding protein 2" O75592 13 77042474-77327094 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Biological rhythms, Ubl conjugation pathway" "Guanine-nucleotide releasing factor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 1066.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058807 Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 2: Non-specific - Mixed function" "Cluster 14: Neurons - Synaptic function" "Cluster 19: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 51 Nucleoplasm "Vesicles, Cytosol" "HPA058807: " "unprognostic (1.35e-3)" "unprognostic (5.86e-2)" "unprognostic (2.80e-1)" "unprognostic (2.84e-2)" "unprognostic (1.72e-1)" "unprognostic (2.99e-1)" "unprognostic (2.88e-1)" "unprognostic (9.83e-3)" "unprognostic (6.96e-2)" "unprognostic (9.76e-3)" "unprognostic (5.88e-3)" "unprognostic (1.17e-1)" "unprognostic (5.51e-3)" "unprognostic (3.73e-3)" "unprognostic (1.52e-1)" "unprognostic (2.62e-1)" "unprognostic (3.26e-2)" "unprognostic (1.53e-1)" "unprognostic (1.17e-2)" "unprognostic (1.30e-1)" "unprognostic (2.84e-1)" "unprognostic (1.19e-3)" "unprognostic (5.31e-2)" "unprognostic (4.53e-2)" "unprognostic (2.25e-1)" "unprognostic (3.00e-3)" "unprognostic (2.96e-1)" "unprognostic (1.66e-1)" "unprognostic (1.27e-1)" "unprognostic (1.75e-2)" "unprognostic (2.02e-1)" MYCBPAP "AMAP-1, DKFZp434N1415" ENSG00000136449 "MYCBP associated protein" Q8TBZ2 17 50508425-50531501 "Essential proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "testis: 61.7" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 38.7;Early spermatids: 256.5;Ependymal cells: 54.2;Fallopian tube ciliated cells: 40.2;Late primary spermatocytes: 233.1;Late spermatids: 201.8;Respiratory ciliated cells: 87.1" "Cell type enriched" "Detected in all" 4 "ependymal cell: 56.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA023257 Enhanced Approved Vesicles NA NA "Cluster 47: Testis - Mixed function" "Cluster 17: Choroid plexus - Cilium" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" 14 Vesicles "HPA023257: " "unprognostic (3.05e-1)" "unprognostic (1.75e-1)" "unprognostic (2.26e-2)" "potential prognostic unfavorable (3.00e-4)" "unprognostic (2.03e-2)" "unprognostic (8.26e-2)" "unprognostic (1.43e-3)" "unprognostic (2.74e-1)" "unprognostic (1.30e-1)" MYCL "bHLHe38, LMYC, MYCL1" ENSG00000116990 "MYCL proto-oncogene, bHLH transcription factor" P12524 1 39895426-39902256 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 63.9;skin 1: 37.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 43.5;Esophageal suprabasal cells: 30.6;Hepatocytes: 31.2;pDCs: 28.1;Prostatic hillock cells: 40.7;Respiratory deuterosomal cells: 79.8;Respiratory secretory cells: 26.1;Retinal pigment epithelial cells: 25.6;Urothelial cells: 85.7" "Group enriched" "Detected in some" 4 "central nervous system macrophage: 3.7;committed oligodendrocyte precursor: 11.6" "Cancer enhanced" "Detected in all" "Bladder Urothelial Carcinoma (TCGA): 63.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 17.3;intermediate monocyte: 8.2;myeloid DC: 18.7;plasmacytoid DC: 22.8" "Group enriched" "Detected in many" 72 "dendritic cells: 22.8;monocytes: 17.3" "Cancer enhanced" "Detected in many" "lung cancer: 54.1;Myeloma: 31.7" "Breast - Breast glandular cells, Liver - Hepatocytes, Pituitary gland - Corticotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063132, HPA074515" Enhanced "Nucleoplasm,Mitotic chromosome" Yes NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 8: Pancreas - Proteolysis" "Cluster 33: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 69: Urothelial cells - Basic cellular functions" 4 Nucleoplasm "Mitotic chromosome" "HPA063132: , HPA074515: " "unprognostic (1.23e-2)" "unprognostic (1.09e-1)" "unprognostic (1.38e-1)" "unprognostic (8.05e-2)" "unprognostic (1.51e-1)" "unprognostic (2.12e-2)" "potential prognostic favorable (1.07e-4)" "unprognostic (7.28e-3)" "unprognostic (3.12e-1)" "unprognostic (4.92e-3)" "unprognostic (1.34e-1)" "unprognostic (3.50e-2)" "unprognostic (1.74e-2)" "unprognostic (6.04e-3)" "unprognostic (5.31e-2)" "unprognostic (3.17e-2)" "unprognostic (6.11e-2)" "unprognostic (5.24e-2)" "unprognostic (1.16e-2)" "unprognostic (3.66e-2)" "unprognostic (4.83e-2)" "unprognostic (2.01e-1)" "unprognostic (2.14e-2)" "unprognostic (6.57e-3)" "unprognostic (1.79e-1)" "unprognostic (1.47e-2)" "unprognostic (7.16e-2)" "unprognostic (1.33e-2)" "unprognostic (2.67e-1)" MYCN "bHLHe37, MYCNOT, N-myc, NMYC" ENSG00000134323 "MYCN proto-oncogene, bHLH transcription factor" P04198 2 15940550-15947007 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.8;placenta: 7.7" "Cell type enriched" "Detected in some" 6 "Extravillous trophoblasts: 124.0" "Cell type enhanced" "Detected in many" "midbrain-derived inhibitory: 13.5;oligodendrocyte precursor cell: 14.0" "Cancer enriched" "Detected in many" 6 "Testicular Germ Cell Tumor (TCGA): 85.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 17 "Neuroblastoma: 615.1" "Skeletal muscle - Fibroblasts, Skin - Inner root sheath cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA057420 Approved Nucleoplasm,Nucleoli NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 30: White matter - Myelination" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 49 Nucleoli Nucleoplasm "HPA057420: " "unprognostic (1.35e-1)" "unprognostic (1.19e-1)" "unprognostic (2.51e-1)" "unprognostic (3.23e-2)" "unprognostic (2.36e-1)" "unprognostic (4.18e-2)" "unprognostic (1.12e-1)" "potential prognostic favorable (1.47e-5)" "unprognostic (2.13e-2)" "unprognostic (2.19e-1)" "potential prognostic favorable (1.51e-4)" "unprognostic (1.09e-2)" "potential prognostic favorable (3.54e-4)" "unprognostic (2.55e-1)" "unprognostic (5.53e-3)" "unprognostic (2.56e-2)" "unprognostic (1.82e-1)" "unprognostic (3.90e-3)" "unprognostic (3.38e-1)" "unprognostic (2.21e-2)" "unprognostic (3.52e-1)" "unprognostic (1.13e-1)" "unprognostic (1.85e-2)" "unprognostic (8.98e-2)" "unprognostic (3.62e-2)" "unprognostic (5.16e-2)" "unprognostic (4.59e-2)" MYCT1 "FLJ21269, MTLC" ENSG00000120279 "MYC target 1" Q8N699 6 152697897-152724569 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 46.7" "Group enriched" "Detected in some" 4 "Hematopoietic stem cells: 162.5;Lymphatic endothelial cells: 141.3;Megakaryocyte progenitors: 68.7;Megakaryocyte-Erythroid progenitors: 131.3;Megakaryocytes: 43.3;Platelets: 108.9;Vascular endothelial cells: 149.2" "Cell type enriched" "Detected in some" 21 "endothelial cell: 151.9" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 16.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 33 "eosinophil: 30.7" "Lineage enriched" "Detected in single" 246 "granulocytes: 30.7" "Cancer enhanced" "Detected in some" "Leukemia: 3.6;thyroid cancer: 5.7" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Spleen - Endothelial cells, Stomach - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA047992 Supported "Nucleoplasm,Nuclear bodies,Vesicles" NA NA 53000 "Cluster 22: Eosinophils - Transcription" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 4 Nucleoplasm "Nuclear bodies, Vesicles" "HPA047992: " "unprognostic (4.13e-1)" "unprognostic (3.88e-1)" "unprognostic (2.57e-1)" "unprognostic (2.04e-1)" "unprognostic (1.02e-1)" "unprognostic (3.00e-2)" "unprognostic (1.11e-1)" "unprognostic (6.50e-2)" "unprognostic (1.75e-1)" "unprognostic (9.47e-2)" "validated prognostic favorable (1.55e-8)" "validated prognostic favorable (1.23e-4)" "unprognostic (4.75e-3)" "unprognostic (3.55e-3)" "potential prognostic favorable (1.86e-5)" "unprognostic (7.40e-2)" "unprognostic (2.08e-1)" "potential prognostic unfavorable (3.02e-4)" "unprognostic (4.47e-2)" "unprognostic (2.98e-1)" "unprognostic (1.42e-1)" "unprognostic (2.54e-2)" "unprognostic (1.33e-1)" "unprognostic (9.33e-3)" "unprognostic (2.43e-2)" "unprognostic (8.96e-3)" "unprognostic (1.27e-1)" "unprognostic (2.06e-3)" "unprognostic (1.61e-1)" "unprognostic (6.65e-2)" "unprognostic (1.30e-1)" MYD88 ENSG00000172936 "MYD88 innate immune signal transduction adaptor" Q99836 3 38138478-38143024 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Antiviral defense, Immunity, Inflammatory response, Innate immunity" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "cDC: 59.1;Esophageal apical cells: 111.1;Kupffer cells: 95.3;monocytes: 111.1;Neutrophil progenitors: 61.8;Neutrophils: 255.1;Ocular epithelial cells: 64.5" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 10.8;leukocyte: 19.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB009104 Approved Supported Vesicles,Mitochondria,Cytosol NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 5: Spleen - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 57 Cytosol "Vesicles, Mitochondria" "CAB009104: " "potential prognostic favorable (3.15e-4)" "unprognostic (4.04e-3)" "unprognostic (3.09e-2)" "unprognostic (1.11e-1)" "unprognostic (1.08e-1)" "unprognostic (5.60e-2)" "unprognostic (7.02e-2)" "potential prognostic unfavorable (7.08e-4)" "unprognostic (9.02e-3)" "unprognostic (2.18e-2)" "potential prognostic favorable (9.27e-4)" "unprognostic (9.54e-2)" "unprognostic (2.61e-1)" "unprognostic (9.76e-2)" "unprognostic (8.99e-2)" "unprognostic (2.06e-1)" "unprognostic (7.23e-3)" "unprognostic (2.79e-1)" "unprognostic (4.80e-2)" "unprognostic (7.44e-2)" "unprognostic (1.19e-1)" "unprognostic (7.20e-3)" "unprognostic (2.40e-1)" "unprognostic (6.48e-2)" "unprognostic (3.81e-2)" "unprognostic (1.28e-1)" "unprognostic (8.29e-2)" "unprognostic (2.69e-1)" "unprognostic (6.02e-2)" "unprognostic (2.34e-1)" "unprognostic (1.01e-1)" MYDGF "C19orf10, IL-25, IL-27, IL25, IL27, IL27w, R33729_1, SF20" ENSG00000074842 "Myeloid derived growth factor" Q969H8 19 4641374-4670362 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Apoptosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Decidual stromal cells: 467.7;Epididymal principal cells: 792.0;Extravillous trophoblasts: 1065.7;Plasma cells: 792.8;Syncytiotrophoblasts: 731.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041872, HPA046744" Approved "Secreted to blood" "Developmental protein" NA NA 285000 2700000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 70: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 8: Non-specific - Secretory pathway" 16 "HPA041872: , HPA046744: " "unprognostic (1.11e-1)" "unprognostic (9.01e-2)" "unprognostic (3.39e-2)" "unprognostic (1.60e-1)" "unprognostic (3.48e-2)" "unprognostic (1.52e-2)" "unprognostic (3.00e-2)" "unprognostic (2.13e-2)" "unprognostic (8.69e-2)" "unprognostic (4.60e-3)" "potential prognostic unfavorable (7.25e-5)" "potential prognostic unfavorable (6.57e-6)" "unprognostic (1.23e-3)" "unprognostic (1.93e-2)" "unprognostic (2.51e-2)" "unprognostic (1.96e-1)" "unprognostic (2.10e-1)" "unprognostic (2.14e-1)" "unprognostic (1.17e-2)" "unprognostic (2.02e-1)" "unprognostic (3.88e-1)" "unprognostic (1.56e-1)" "unprognostic (2.62e-1)" "unprognostic (1.39e-1)" "unprognostic (1.10e-1)" "unprognostic (1.72e-1)" "unprognostic (3.46e-1)" "unprognostic (6.42e-2)" "potential prognostic favorable (8.91e-4)" MYEF2 "FLJ11213, HsT18564, KIAA1341, MEF-2" ENSG00000104177 "Myelin expression factor 2" 15 48134632-48178353 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Corticotrophs: 229.0;Gonadotrophs: 218.8;Lactotrophs: 374.8;Pituicytes/FSCs: 277.2;Sertoli cells: 216.5;Somatotrophs: 286.7;Thyrotrophs: 326.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Smooth muscle cells, Spleen - Endothelial cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004883 Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 16: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 4 Nucleoplasm Cytosol "HPA004883: " "unprognostic (1.39e-1)" "unprognostic (3.86e-3)" "unprognostic (5.64e-1)" "unprognostic (1.08e-1)" "unprognostic (8.38e-2)" "unprognostic (1.61e-2)" "unprognostic (2.55e-2)" "unprognostic (2.15e-2)" "potential prognostic unfavorable (5.22e-5)" "validated prognostic favorable (2.98e-7)" "validated prognostic favorable (2.22e-5)" "unprognostic (2.53e-1)" "unprognostic (2.08e-3)" "unprognostic (7.34e-3)" "unprognostic (1.35e-2)" "unprognostic (2.99e-1)" "unprognostic (8.49e-2)" "unprognostic (7.39e-3)" "unprognostic (1.40e-1)" "unprognostic (1.34e-1)" "potential prognostic favorable (8.04e-5)" "unprognostic (2.66e-1)" "unprognostic (5.92e-2)" "unprognostic (1.88e-1)" "unprognostic (1.53e-1)" "unprognostic (1.19e-1)" "unprognostic (4.93e-2)" "unprognostic (1.76e-2)" "unprognostic (1.65e-1)" "unprognostic (1.62e-1)" MYEOV OCIM ENSG00000172927 "Myeloma overexpressed" Q96EZ4 11 69294151-69341682 "Predicted membrane proteins" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 5.5;esophagus: 10.8;stomach 1: 5.7" "Cell type enriched" "Detected in some" 6 "Esophageal apical cells: 291.1" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 1.5;oligodendrocyte precursor cell: 1.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Prostate - Urothelial cells, Stomach - Gastric mucous cells" HPA012949 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 84: Apical squamous epithelium - Cornification" 11 Nucleoplasm Vesicles "HPA012949: " "unprognostic (4.23e-1)" "potential prognostic favorable (1.36e-4)" "unprognostic (8.65e-2)" "potential prognostic favorable (3.96e-5)" "unprognostic (4.38e-1)" "unprognostic (1.07e-1)" "unprognostic (8.04e-2)" "unprognostic (3.03e-1)" "unprognostic (8.67e-2)" "unprognostic (2.47e-2)" "unprognostic (2.62e-1)" "unprognostic (1.06e-3)" "unprognostic (2.52e-1)" "unprognostic (1.79e-2)" "unprognostic (3.71e-2)" "unprognostic (8.33e-2)" "potential prognostic unfavorable (2.77e-6)" "unprognostic (1.44e-1)" "unprognostic (7.40e-2)" "unprognostic (7.91e-2)" "unprognostic (2.36e-1)" "unprognostic (2.14e-1)" "unprognostic (1.72e-1)" MYF5 bHLHc2 ENSG00000111049 "Myogenic factor 5" P13349 12 80716912-80719671 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Myogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 23 "skeletal muscle: 5.2;tongue: 8.3" "Cell type enriched" "Detected in single" 559 "Myosatellite cells: 176.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 9 "Sarcoma: 4.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA041691 Supported Nucleoplasm NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 22 Nucleoplasm "HPA041691: " MYF6 "bHLHc4, MRF4" ENSG00000111046 "Myogenic factor 6" P23409 12 80707634-80709474 "Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Myogenesis" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 37 "skeletal muscle: 471.7;tongue: 193.8" "Cell type enriched" "Detected in some" 4 "Thymic myoid cells: 596.9" "Cell type enhanced" "Detected in single" "pericyte: 1.2" "Cancer enriched" "Detected in some" 5 "Head and Neck Squamous Cell Carcinoma (TCGA): 5.0" "Region enriched" "Detected in single" 4 "thalamus: 1.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Sarcoma: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA065102 Supported "Nucleoplasm,Mitotic spindle,Cytosol" Yes NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 4 Nucleoplasm "Mitotic spindle, Cytosol" "HPA065102: " "potential prognostic unfavorable (7.06e-5)" MYG1 "C12orf10, Gamm1, MYG" ENSG00000139637 "MYG1 exonuclease" Q9HB07 12 53299695-53307177 "Disease related genes, Essential proteins, Predicted intracellular proteins" "Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 7.7;Bergmann glia: 8.7;Brain excitatory neurons: 16.0;Brain inhibitory neurons: 14.3;Ependymal cells: 11.9;Late spermatids: 8.5;Oligodendrocytes: 11.6;Other brain neurons: 26.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038626, HPA038627" Approved Supported Supported Nucleoplasm NA NA 15000 "Cluster 33: Non-specific - ATP binding" "Cluster 67: Testis - Mixed function" "Cluster 45: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 98: Neurons - Neurotransmission & signaling" 37 Nucleoplasm "HPA038626: , HPA038627: " "unprognostic (7.98e-2)" "unprognostic (2.12e-1)" "unprognostic (2.23e-1)" "unprognostic (2.13e-1)" "unprognostic (4.82e-1)" "unprognostic (3.11e-1)" "unprognostic (1.99e-1)" "unprognostic (7.75e-2)" "unprognostic (9.17e-3)" "unprognostic (2.86e-2)" "unprognostic (5.04e-1)" "unprognostic (1.62e-2)" "potential prognostic unfavorable (4.54e-4)" "unprognostic (1.91e-3)" "unprognostic (5.77e-3)" "unprognostic (1.10e-1)" "unprognostic (1.22e-1)" "unprognostic (2.04e-1)" "unprognostic (2.50e-1)" "unprognostic (2.24e-1)" "unprognostic (7.00e-2)" "unprognostic (9.96e-2)" "unprognostic (2.81e-1)" "unprognostic (1.43e-1)" "unprognostic (2.56e-1)" "unprognostic (5.59e-3)" "unprognostic (6.18e-2)" "unprognostic (1.63e-1)" "unprognostic (8.12e-3)" MYH1 "MGC133384, MYHa, MyHC-2X/D, MYHSA1" ENSG00000109061 "Myosin heavy chain 1" P12882 17 10492307-10518542 "Plasma proteins, Predicted intracellular proteins" Hearing "Actin-binding, Calmodulin-binding, Motor protein, Muscle protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 137 "skeletal muscle: 7384.5" "Group enriched" "Detected in some" 24 "Myonuclei: 706.2;Thymic myoid cells: 186.3" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 44 "Head and Neck Squamous Cell Carcinoma (TCGA): 13.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skeletal muscle - Skeletal myocytes, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA001349, CAB010759" Enhanced Uncertain "Focal adhesion sites" NA NA 17000000 "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 11 "Focal adhesion sites" "CAB010759: , HPA001349: " "unprognostic (3.05e-3)" MYH10 NMMHCB ENSG00000133026 "Myosin heavy chain 10" P35580 17 8474207-8631376 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Cell shape" "Actin-binding, Calmodulin-binding, Host cell receptor for virus entry, Motor protein, Myosin, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "blood vessel: 253.8" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 378.9;Epicardial cells: 723.2;Hepatic stellate cells: 387.3;Mesothelial cells: 335.7;Thyrotrophs: 352.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Heart muscle - Smooth muscle cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblasts_1, Skeletal muscle - Fibroblasts, Testis - Spermatogonia, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "CAB017180, HPA047541, HPA057198" Enhanced Uncertain "Actin filaments,Mitochondria,Cytosol" NA NA 41000000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 69: Skin cancer - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 46 "Actin filaments" "Mitochondria, Cytosol" "CAB017180: , HPA047541: , HPA057198: " "unprognostic (3.73e-1)" "unprognostic (2.03e-1)" "potential prognostic favorable (5.26e-4)" "unprognostic (8.12e-3)" "unprognostic (9.11e-2)" "unprognostic (1.54e-1)" "unprognostic (3.24e-1)" "potential prognostic favorable (1.72e-4)" "unprognostic (2.29e-2)" "unprognostic (7.80e-3)" "potential prognostic favorable (6.28e-6)" "unprognostic (2.17e-3)" "unprognostic (1.82e-1)" "unprognostic (2.56e-1)" "unprognostic (1.08e-1)" "unprognostic (4.62e-2)" "unprognostic (2.86e-1)" "unprognostic (4.74e-2)" "unprognostic (2.97e-1)" "unprognostic (1.04e-1)" "unprognostic (7.44e-3)" "potential prognostic favorable (3.40e-4)" "unprognostic (3.24e-1)" "unprognostic (6.15e-2)" "unprognostic (9.55e-2)" "unprognostic (1.67e-1)" "unprognostic (3.18e-2)" "unprognostic (7.81e-3)" "unprognostic (2.60e-1)" "unprognostic (7.52e-2)" "unprognostic (8.71e-2)" MYH11 "SMHC, SMMHC, SMMS-1" ENSG00000133392 "Myosin heavy chain 11" P35749 16 15703135-15857028 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Muscle protein, Myosin" "Aortic aneurysm, Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 2385.4;intestine: 3136.0;urinary bladder: 2375.2" "Group enriched" "Detected in many" 4 "Peritubular myoid cells: 550.0;Smooth muscle cells: 1993.2;Vascular smooth muscle cells: 1312.5" "Cell type enriched" "Detected in many" 28 "vascular associated smooth muscle cell: 1444.2" "Group enriched" "Detected in all" 4 "Prostate Adenocarcinoma (TCGA): 439.6;Stomach Adenocarcinoma (TCGA): 369.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lymphoma: 3.4;Rhabdoid: 1.7" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Adrenal gland - Smooth muscle cells, Breast - Breast myoepithelial cells, Colon - Smooth muscle cells, Heart muscle - Smooth muscle cells, Kidney - Fibroblasts, Lung - Smooth muscle cells, Minor Salivary Gland - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Skin - Smooth muscle cells, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "midbrain: 52.0" "CAB002302, HPA014539, HPA015310" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA 37000000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 55: Lymphoma - Immune response" "Cluster 62: Smooth muscle cells - Muscle contraction" 8 "Plasma membrane, Cytosol" "CAB002302: , HPA014539: , HPA015310: " "potential prognostic favorable (8.33e-4)" "unprognostic (1.07e-1)" "unprognostic (1.38e-1)" "unprognostic (4.24e-2)" "unprognostic (1.49e-1)" "unprognostic (2.04e-2)" "unprognostic (9.34e-2)" "unprognostic (2.72e-2)" "unprognostic (1.40e-2)" "unprognostic (9.54e-2)" "unprognostic (3.54e-3)" "potential prognostic favorable (1.59e-4)" "potential prognostic unfavorable (5.83e-4)" "potential prognostic favorable (2.96e-6)" "unprognostic (8.18e-2)" "unprognostic (5.12e-2)" "unprognostic (2.08e-1)" "unprognostic (4.69e-2)" "unprognostic (1.33e-1)" "unprognostic (9.29e-2)" "unprognostic (6.13e-3)" "unprognostic (1.92e-1)" "potential prognostic favorable (4.81e-4)" "unprognostic (8.72e-2)" "unprognostic (6.70e-2)" "unprognostic (2.05e-2)" "unprognostic (6.42e-2)" "unprognostic (5.12e-2)" "unprognostic (1.30e-1)" "unprognostic (8.54e-2)" "unprognostic (3.52e-3)" MYH13 MyHC-eo ENSG00000006788 "Myosin heavy chain 13" Q9UKX3 17 10300865-10373130 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Muscle protein, Myosin" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skeletal muscle: 1.4;stomach 1: 1.5" "Cell type enhanced" "Detected in some" "Adipocytes: 25.9;Differentiating spermatogonia: 11.1;Early primary spermatocytes: 7.5;Epicardial cells: 25.0;Fibro-adipogenic progenitors: 19.8;Fibroblasts: 15.3;Hepatic stellate cells: 6.5;Oocytes: 27.6;Undifferentiated spermatogonia: 10.0" "Low cell type specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in single" "Not detected" "Not detected" NA NA 11000000 "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 35: RS4;11 - Unknown function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 3 MYH14 "DFNA4, FLJ13881, KIAA2034, MHC16, MYH17" ENSG00000105357 "Myosin heavy chain 14" Q7Z406 19 50188186-50310542 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell shape" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Deafness, Disease variant, Neuropathy, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 70.3;skeletal muscle: 133.3" "Cell type enhanced" "Detected in many" "Colonocytes: 1267.1;Enteric transient amplifying cells: 437.5;Enterocytes: 965.5;Foveolar cells: 479.3;Goblet cells: 353.6;Ocular epithelial cells: 560.8;Respiratory secretory cells: 356.5;Urothelial cells: 435.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Colon - Colon enterocytes, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Stomach - Gastric mucous cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062391, HPA067889, HPA070260" Enhanced Approved Nucleoplasm NA NA 26000000 "Cluster 63: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 22 Nucleoplasm "HPA062391: , HPA067889: , HPA070260: " "potential prognostic favorable (8.74e-6)" "unprognostic (2.36e-1)" "potential prognostic favorable (2.71e-4)" "unprognostic (1.03e-1)" "unprognostic (2.92e-2)" "unprognostic (1.64e-1)" "unprognostic (1.50e-1)" "unprognostic (1.68e-2)" "unprognostic (1.74e-1)" "unprognostic (1.31e-1)" "potential prognostic favorable (4.58e-5)" "unprognostic (1.29e-1)" "unprognostic (6.50e-2)" "unprognostic (1.03e-1)" "unprognostic (4.60e-2)" "unprognostic (4.63e-2)" "unprognostic (1.56e-1)" "unprognostic (7.50e-2)" "unprognostic (1.25e-1)" "unprognostic (2.86e-2)" "unprognostic (3.77e-2)" "unprognostic (6.09e-3)" "unprognostic (9.83e-2)" "unprognostic (3.89e-2)" "unprognostic (9.08e-2)" "unprognostic (3.74e-2)" "unprognostic (2.73e-1)" "unprognostic (2.50e-3)" "unprognostic (9.97e-2)" "unprognostic (1.15e-1)" "unprognostic (1.36e-1)" MYH15 KIAA1000 ENSG00000144821 "Myosin heavy chain 15" Q9Y2K3 3 108380368-108529322 "Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Muscle protein, Myosin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "retina: 3.0;tongue: 1.9" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 42.5;Alveolar cells type 1: 13.6;Astrocytes: 26.7;Bergmann glia: 38.1;Cone photoreceptor cells: 16.6;Ependymal cells: 14.6;Müller glia: 18.9;Oligodendrocytes: 14.2;Oocytes: 13.8;Rod photoreceptor cells: 14.9" "Cell type enhanced" "Detected in many" "astrocyte: 30.6;Bergmann glia: 35.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 9.4" "Pituitary gland - Thyrotropes, Prostate - Prostate glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA034871, HPA057915" Uncertain Approved Vesicles,Cytosol NA NA "Cluster 42: Retina - Visual perception" "Cluster 19: Astrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 28: Astrocytes - Homeostasis & neuron support" 3 Cytosol Vesicles "HPA034871: , HPA057915: " "unprognostic (3.50e-2)" MYH2 "IBM3, MYH2A, MYHas8, MyHC-2A, MyHC-IIa, MYHSA2" ENSG00000125414 "Myosin heavy chain 2" Q9UKX2 17 10521148-10549700 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Muscle protein, Myosin" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 80 "skeletal muscle: 11977.3;tongue: 5736.0" "Group enriched" "Detected in some" 68 "Myonuclei: 699.1;Thymic myoid cells: 1975.5" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 62 "Head and Neck Squamous Cell Carcinoma (TCGA): 46.8" "Region enhanced" "Detected in some" "amygdala: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 2.2;testis cancer: 1.6" "Skeletal muscle - Skeletal myocytes" "HPA001349, CAB010760" Enhanced Uncertain "Focal adhesion sites" NA NA 17000000 "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 29: Forebrain - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 3 "Focal adhesion sites" "CAB010760: , HPA001349: " "unprognostic (1.80e-2)" MYH3 "HEMHC, MYHC-EMB, MYHSE1, SMHCE" ENSG00000109063 "Myosin heavy chain 3" P11055 17 10628526-10657309 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Muscle protein, Myosin" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 27.1;seminal vesicle: 17.2;skeletal muscle: 20.2" "Group enriched" "Detected in many" 5 "Early spermatids: 427.0;Late primary spermatocytes: 297.2;Thymic myoid cells: 131.9" "Cell type enhanced" "Detected in many" "deep-layer near-projecting: 11.3" "Cancer enhanced" "Detected in some" "Prostate Adenocarcinoma (TCGA): 6.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 9 "Sarcoma: 21.8" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA021808 Enhanced NA NA 6200000 "Cluster 25: Non-specific - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 3 "HPA021808: " "unprognostic (1.39e-2)" "unprognostic (1.11e-1)" "unprognostic (4.96e-3)" "unprognostic (1.14e-1)" "unprognostic (2.29e-1)" "unprognostic (1.64e-3)" "unprognostic (1.25e-1)" "unprognostic (2.14e-3)" "unprognostic (2.94e-2)" "unprognostic (1.22e-1)" "unprognostic (8.53e-3)" MYH4 "MYH2B, MyHC-2B, MyHC-IIb" ENSG00000264424 "Myosin heavy chain 4" Q9Y623 17 10443290-10469559 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Muscle protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 65 "skeletal muscle: 9.9" "Group enriched" "Detected in some" 4 "Adipocytes: 8.6;Early primary spermatocytes: 12.9;Epicardial cells: 11.4;Fibro-adipogenic progenitors: 5.3;Fibroblasts: 6.1;Myonuclei: 7.0;Myosatellite cells: 8.2;Tuft cells: 11.5" "Cell type enhanced" "Detected in single" "deep-layer near-projecting: 1.6" "Cancer enriched" "Detected in single" 66 "Liver Hepatocellular Carcinoma (TCGA): 11.0" "Region enhanced" "Detected in single" "amygdala: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" HPA001349 Supported Uncertain "Focal adhesion sites" NA NA 14000000 "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 29: Forebrain - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 6 "Focal adhesion sites" "HPA001349: " "unprognostic (4.56e-2)" "unprognostic (1.96e-2)" MYH6 ENSG00000197616 "Myosin heavy chain 6" P13533 14 23381982-23408273 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Muscle protein, Myosin" "Atrial septal defect, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 30 "heart muscle: 4840.4" "Cell type enriched" "Detected in some" 19 "Cardiomyocytes: 974.1" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "Testicular Germ Cell Tumor (TCGA): 2.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pituitary gland - Corticotropes" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA001239, HPA001349, CAB075723, CAB075724, CAB075725" Enhanced Uncertain "Focal adhesion sites" NA NA 9100000 "Cluster 35: Non-specific - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 1 "Focal adhesion sites" "CAB075723: , CAB075724: , CAB075725: , HPA001239: , HPA001349: " "unprognostic (2.19e-1)" MYH7 "CMD1S, CMH1, MPD1" ENSG00000092054 "Myosin heavy chain 7" P12883 14 23412740-23435660 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Muscle protein, Myosin" "Cardiomyopathy, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 71 "heart muscle: 7145.3;skeletal muscle: 13633.1;tongue: 5024.6" "Group enriched" "Detected in some" 18 "Cardiomyocytes: 2902.2;Myonuclei: 1585.1" "Low cell type specificity" "Detected in some" "Group enriched" "Detected in some" 8 "Head and Neck Squamous Cell Carcinoma (TCGA): 18.6;Prostate Adenocarcinoma (TCGA): 21.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Pituitary gland - Corticotropes, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA001239, HPA001349, CAB015384" Enhanced Uncertain "Focal adhesion sites" NA NA 14000000 "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 55: Myocytes - Oxidative muscle function" 14 "Focal adhesion sites" "CAB015384: , HPA001239: , HPA001349: " "unprognostic (2.50e-1)" "unprognostic (4.28e-2)" "unprognostic (1.12e-2)" "unprognostic (2.19e-1)" MYH7B "dJ756N5.1, KIAA1512, MHC14, MYH14" ENSG00000078814 "Myosin heavy chain 7B" A7E2Y1 20 34955810-35002437 "Predicted intracellular proteins" "Actin-binding, Motor protein, Muscle protein, Myosin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "heart muscle: 338.7;skeletal muscle: 147.2" "Group enriched" "Detected in many" 4 "Cardiomyocytes: 309.2;Myonuclei: 582.0" "Cell type enhanced" "Detected in all" "oligodendrocyte: 21.8" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 13.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 5.4;Gastric cancer: 5.0" "Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Testis - Late spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" NA NA 1200000 "Cluster 41: Striated muscle - Muscle contraction" "Cluster 6: Non-specific - Immune response" "Cluster 32: Non-specific - Cell proliferation" "Cluster 55: Myocytes - Oxidative muscle function" 5 "unprognostic (3.49e-2)" "unprognostic (6.16e-2)" "potential prognostic favorable (5.55e-6)" "unprognostic (1.70e-2)" "unprognostic (5.75e-2)" "unprognostic (1.05e-1)" "unprognostic (5.40e-2)" "unprognostic (1.21e-1)" "unprognostic (4.20e-2)" "unprognostic (8.08e-3)" "unprognostic (3.57e-2)" "unprognostic (3.21e-1)" "unprognostic (3.91e-2)" "unprognostic (8.65e-3)" "unprognostic (3.26e-1)" "unprognostic (2.05e-2)" "unprognostic (1.98e-1)" "unprognostic (2.75e-2)" "unprognostic (2.07e-1)" "unprognostic (2.21e-1)" "unprognostic (9.53e-2)" MYH8 "MyHC-peri, MyHC-pn" ENSG00000133020 "Myosin heavy chain 8" P13535 17 10390322-10421950 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Muscle protein, Myosin" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "esophagus: 15.0;lymphoid tissue: 10.0;skeletal muscle: 16.1;tongue: 9.4" "Group enriched" "Detected in some" 4 "Myonuclei: 16.5;Thymic myoid cells: 53.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Head and Neck Squamous Cell Carcinoma (TCGA): 1.0;Kidney Renal Clear Cell Carcinoma (TCGA): 1.5;Kidney Renal Papillary Cell Carcinoma (TCGA): 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 16 "Rhabdoid: 10.1" "Kidney - Ascending Loop of Henle cells, Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001349, CAB016527" Enhanced Uncertain "Focal adhesion sites" NA NA 11000000 "Cluster 63: Non-specific - Basic cellular processes" "Cluster 5: Rhabdoid - Unknown function" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 7 "Focal adhesion sites" "CAB016527: , HPA001349: " "unprognostic (3.52e-3)" "unprognostic (2.37e-2)" "unprognostic (1.07e-2)" "unprognostic (3.37e-3)" MYH9 "DFNA17, EPSTS, FTNS, MHA, NMHC-II-A, NMMHCA" ENSG00000100345 "Myosin heavy chain 9" P35579 22 36281280-36388010 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Cell shape" "Actin-binding, Calmodulin-binding, Host cell receptor for virus entry, Motor protein, Myosin, Receptor" "Alport syndrome, Cancer-related genes, Cataract, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 530.2" "Cell type enhanced" "Detected in many" "Neutrophil progenitors: 1041.5;Neutrophils: 1873.8;Pancreatic acinar cells: 1111.2;Platelets: 1643.8" "Cell type enhanced" "Detected in all" "endothelial cell: 385.5;leukocyte: 332.7;vascular associated smooth muscle cell: 382.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001644, CAB015386, HPA064783" Enhanced Supported "Nuclear bodies,Plasma membrane,Actin filaments,Cytosol" No No 630000000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 47: Endothelial cells - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 156 "Plasma membrane, Actin filaments" "Nuclear bodies, Cytosol" "CAB015386: , HPA001644: , HPA064783: " "unprognostic (3.63e-2)" "unprognostic (3.27e-1)" "unprognostic (3.22e-1)" "unprognostic (1.26e-3)" "unprognostic (6.75e-2)" "unprognostic (3.86e-1)" "unprognostic (4.15e-1)" "unprognostic (1.70e-2)" "unprognostic (2.75e-3)" "unprognostic (5.55e-2)" "potential prognostic favorable (7.09e-5)" "unprognostic (1.48e-3)" "unprognostic (1.71e-1)" "unprognostic (5.07e-2)" "unprognostic (1.71e-1)" "unprognostic (6.74e-2)" "potential prognostic unfavorable (2.17e-5)" "unprognostic (4.63e-1)" "unprognostic (3.22e-1)" "unprognostic (4.29e-2)" "unprognostic (1.15e-1)" "unprognostic (3.49e-2)" "unprognostic (8.07e-2)" "unprognostic (2.36e-1)" "unprognostic (2.28e-2)" "unprognostic (8.78e-3)" "unprognostic (4.05e-1)" "unprognostic (2.77e-1)" "unprognostic (1.28e-1)" "unprognostic (1.22e-2)" "unprognostic (2.97e-1)" MYL1 "MLC-1, MLC1, MLC1/3, MLC1F, MLC3F" ENSG00000168530 "Myosin light chain 1" P05976 2 210290150-210315174 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Motor protein, Muscle protein, Myosin" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 87 "skeletal muscle: 20434.9;tongue: 14550.6" "Cell type enriched" "Detected in some" 4 "Thymic myoid cells: 2818.5" "Not detected" "Not detected" "Group enriched" "Detected in some" 18 "Head and Neck Squamous Cell Carcinoma (TCGA): 89.3;Prostate Adenocarcinoma (TCGA): 28.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 17 "Sarcoma: 37.9" "Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes" "Region enriched" "Detected in single" 4 "olfactory bulb: 4.0" "Low region specificity" "Detected in all" "HPA046859, HPA063034, HPA073827" Enhanced NA NA 10000000 "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 5 "HPA046859: , HPA063034: , HPA073827: " "unprognostic (1.88e-3)" "unprognostic (7.61e-2)" "unprognostic (1.28e-1)" MYL10 "MGC3479, MYLC2PL, PLRLC" ENSG00000106436 "Myosin light chain 10" Q9BUA6 7 101613330-101629296 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "skeletal muscle: 1.3" "Group enriched" "Detected in some" 4 "Epididymal principal cells: 11.2;Peritubular myoid cells: 3.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Skin Cutaneous Melanoma (TCGA): 1.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 1.9" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.9" "Cancer enriched" "Detected in some" 5 "Rhabdoid: 10.3" "Pituitary gland - Somatotropes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA019763, HPA039262" Uncertain Uncertain Microtubules NA NA 18000 "Cluster 35: Neutrophils - Protein binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 48: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 17 Microtubules "HPA019763: , HPA039262: " "unprognostic (4.75e-2)" "unprognostic (1.23e-2)" "unprognostic (8.90e-2)" "unprognostic (7.22e-2)" MYL11 "HUMMLC2B, MRLC2, MYLPF" ENSG00000180209 "Myosin light chain 11" Q96A32 16 30370934-30377991 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Motor protein, Muscle protein, Myosin" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 97 "skeletal muscle: 18663.7;tongue: 5522.8" "Cell type enriched" "Detected in many" 16 "Thymic myoid cells: 3960.6" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in some" 5 "Head and Neck Squamous Cell Carcinoma (TCGA): 47.5" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 73 "plasmacytoid DC: 19.7" "Lineage enriched" "Detected in single" 73 "dendritic cells: 19.7" "Cancer enriched" "Detected in some" 4 "Sarcoma: 57.6" "Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039262, HPA055059" Enhanced NA NA 860000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 15: Non-specific - Transcription" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 7 "HPA039262: , HPA055059: " "unprognostic (5.16e-1)" "unprognostic (2.55e-1)" "unprognostic (2.64e-3)" "unprognostic (1.37e-1)" "unprognostic (1.70e-1)" "unprognostic (6.59e-2)" "unprognostic (2.63e-1)" MYL12A "MLCB, MRCL3, MRLC3, MYL2B" ENSG00000101608 "Myosin light chain 12A" P19105 18 3247481-3256236 "Predicted intracellular proteins" "Motor protein, Muscle protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "heart muscle: 3965.3;skeletal muscle: 3053.6;tongue: 1943.8" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 5197.4;Extravillous trophoblasts: 1632.1;Megakaryocytes: 3659.5;Neutrophils: 1588.9;Platelets: 4562.3" "Cell type enhanced" "Detected in many" "endothelial cell: 143.1;leukocyte: 218.0;pericyte: 144.1;vascular associated smooth muscle cell: 106.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "CAB004503, HPA039262, HPA045244, HPA059197" Supported NA Yes 39000000 "Cluster 41: Basophils - Unknown function" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 21: Non-specific - Metabolism" "Cluster 13: Non-specific - Mixed function" "Cluster 47: Platelets - Hemostasis" 24 "CAB004503: , HPA039262: , HPA045244: , HPA059197: " "unprognostic (3.06e-2)" "unprognostic (3.04e-2)" "unprognostic (4.39e-2)" "unprognostic (1.98e-1)" "unprognostic (2.37e-1)" "unprognostic (1.05e-1)" "unprognostic (4.67e-3)" "potential prognostic unfavorable (3.56e-5)" "unprognostic (9.90e-3)" "unprognostic (1.89e-1)" "potential prognostic favorable (1.32e-4)" "unprognostic (1.32e-2)" "unprognostic (3.00e-1)" "unprognostic (9.56e-2)" "unprognostic (2.16e-1)" "unprognostic (3.40e-3)" "unprognostic (1.14e-1)" "unprognostic (1.07e-2)" "unprognostic (7.00e-3)" "unprognostic (4.55e-2)" "unprognostic (2.80e-2)" "unprognostic (1.53e-3)" "unprognostic (3.30e-1)" "unprognostic (1.92e-1)" "unprognostic (3.05e-2)" "unprognostic (3.45e-2)" "unprognostic (3.11e-2)" "unprognostic (1.84e-2)" "unprognostic (4.79e-1)" "unprognostic (9.97e-2)" "unprognostic (1.16e-1)" MYL12B MRLC2 ENSG00000118680 "Myosin light chain 12B" O14950 18 3261479-3278461 "Plasma proteins, Predicted intracellular proteins" "Motor protein, Muscle protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 4984.3;Esophageal suprabasal cells: 1894.7;Syncytiotrophoblasts: 1684.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Fibroblasts_1, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039262, HPA045244, HPA059197" Supported NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 13: Non-specific - Mixed function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 25 "HPA039262: , HPA045244: , HPA059197: " "unprognostic (5.63e-2)" "unprognostic (5.76e-2)" "unprognostic (1.70e-3)" "unprognostic (1.50e-1)" "unprognostic (9.42e-2)" "unprognostic (1.66e-1)" "unprognostic (1.10e-1)" "unprognostic (1.63e-1)" "potential prognostic unfavorable (5.27e-4)" "unprognostic (1.76e-1)" "potential prognostic favorable (2.40e-4)" "unprognostic (3.53e-3)" "unprognostic (1.10e-2)" "unprognostic (2.95e-2)" "unprognostic (1.08e-1)" "unprognostic (1.39e-2)" "unprognostic (3.33e-2)" "unprognostic (2.67e-1)" "unprognostic (1.35e-2)" "unprognostic (6.22e-3)" "unprognostic (1.60e-2)" "unprognostic (6.51e-3)" "unprognostic (1.08e-1)" "unprognostic (2.97e-1)" "unprognostic (1.45e-3)" "unprognostic (7.64e-2)" "unprognostic (1.46e-1)" "unprognostic (1.82e-1)" "unprognostic (1.46e-1)" "unprognostic (4.50e-3)" "unprognostic (6.32e-3)" MYL2 CMH10 ENSG00000111245 "Myosin light chain 2" P10916 12 110910819-110921443 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Motor protein, Muscle protein, Myosin" "Cardiomyopathy, Disease variant, Myofibrillar myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 73 "heart muscle: 27634.5;skeletal muscle: 27153.8;tongue: 18492.7" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 224.4;Myonuclei: 879.8" "Cell type enriched" "Detected in single" 5 "mammillary body: 3.1" "Group enriched" "Detected in some" 41 "Head and Neck Squamous Cell Carcinoma (TCGA): 97.6;Prostate Adenocarcinoma (TCGA): 69.6" "Region enriched" "Detected in some" 6 "hypothalamus: 12.4" "Group enriched" "Detected in some" 12 "memory B-cell: 1.1;naive B-cell: 1.2" "Lineage enriched" "Detected in single" 12 "B-cells: 1.2" "Cancer enriched" "Detected in some" 12 "Rhabdoid: 59.2" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA019763, HPA039262" Supported Uncertain Microtubules NA NA 110000 "Cluster 41: Striated muscle - Muscle contraction" "Cluster 45: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 55: Myocytes - Oxidative muscle function" 9 Microtubules "HPA019763: , HPA039262: " "unprognostic (3.32e-2)" "unprognostic (1.32e-3)" "unprognostic (2.88e-1)" "unprognostic (2.02e-1)" MYL3 "CMH8, MLC1SB, MLC1V, VLC1" ENSG00000160808 "Myosin light chain 3" P08590 3 46835111-46882172 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Motor protein, Muscle protein, Myosin" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 8764.4;skeletal muscle: 4813.6;tongue: 1935.7" "Group enriched" "Detected in many" 9 "Cardiomyocytes: 342.0;Myonuclei: 729.5" "Cell type enriched" "Detected in some" 4 "pericyte: 44.8" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 43.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 7.9" "Adrenal gland - Fibroblasts, Heart muscle - Cardiomyocytes, Prostate - Fibroblasts, Skeletal muscle - Skeletal myocytes, Spleen - Fibroblasts_2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA016564, CAB018662, HPA046859, HPA063034" Enhanced Approved Nucleoli,Mitochondria NA NA 7100000 "Cluster 30: Non-specific - DNA binding" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 44: Non-specific - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 55: Myocytes - Oxidative muscle function" 2 "Nucleoli, Mitochondria" "CAB018662: , HPA016564: , HPA046859: , HPA063034: " "unprognostic (8.48e-2)" "unprognostic (1.05e-1)" "unprognostic (2.29e-1)" "unprognostic (2.59e-1)" "unprognostic (2.52e-2)" "unprognostic (9.56e-2)" "unprognostic (1.63e-3)" "validated prognostic favorable (2.71e-9)" "validated prognostic favorable (5.22e-5)" "potential prognostic favorable (2.25e-8)" "unprognostic (8.64e-2)" "unprognostic (2.44e-2)" "unprognostic (1.92e-1)" "unprognostic (2.42e-2)" "unprognostic (5.34e-3)" "unprognostic (6.55e-2)" "unprognostic (2.13e-1)" "unprognostic (4.74e-2)" "unprognostic (1.49e-3)" "unprognostic (2.47e-2)" "unprognostic (1.51e-1)" "potential prognostic unfavorable (3.72e-5)" "unprognostic (3.17e-2)" MYL4 "ALC1, AMLC, GT1, PRO1957" ENSG00000198336 "Myosin light chain 4" P12829 17 47200446-47223679 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Motor protein, Muscle protein, Myosin" "Atrial fibrillation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 48 "heart muscle: 6049.7" "Group enriched" "Detected in some" 4 "Cone photoreceptor cells: 262.9;Erythrocyte progenitors: 249.2;Erythrocytes: 111.9;Late spermatids: 82.2" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Thyroid Carcinoma (TCGA): 40.6" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 9 "plasmacytoid DC: 1.8" "Lineage enriched" "Detected in single" 9 "dendritic cells: 1.8" "Group enriched" "Detected in some" 22 "Leukemia: 71.4;Sarcoma: 44.7;testis cancer: 22.4" "Heart muscle - Cardiomyocytes, Skin - Fibroblasts_1, Spleen - Erythrocytes, Stomach - Gastric mucous cells" "Group enriched" "Detected in all" 6 "amygdala: 25.8;cerebral cortex: 88.4;hippocampal formation: 25.2;white matter: 50.9" "Not detected" "Not detected" "HPA046859, HPA051884, HPA063034" Enhanced Approved "Plasma membrane" NA NA 250000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 35: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" "Plasma membrane" "HPA046859: , HPA051884: , HPA063034: " "unprognostic (2.04e-1)" "unprognostic (1.06e-2)" "unprognostic (1.65e-1)" "unprognostic (3.59e-3)" "unprognostic (1.63e-2)" "unprognostic (7.25e-2)" "unprognostic (2.42e-1)" "unprognostic (2.60e-2)" MYL5 ENSG00000215375 "Myosin light chain 5" Q02045 4 673580-682028 "Predicted intracellular proteins" "Motor protein, Muscle protein, Myosin" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Cardiomyocytes: 445.1;Late spermatids: 149.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts" "Not detected" "Not detected" "HPA037381, HPA039262" Uncertain Uncertain Nucleoplasm,Nucleoli NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 6: Non-specific - Immune response" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 1 "Nucleoplasm, Nucleoli" "HPA037381: , HPA039262: " "unprognostic (2.71e-1)" "unprognostic (1.09e-2)" "unprognostic (5.39e-2)" "unprognostic (1.63e-2)" "unprognostic (1.08e-1)" "potential prognostic favorable (6.42e-4)" "unprognostic (1.56e-3)" "unprognostic (1.33e-2)" "unprognostic (2.07e-1)" "unprognostic (2.69e-2)" "potential prognostic favorable (2.22e-4)" "unprognostic (1.99e-2)" "unprognostic (2.73e-2)" "unprognostic (2.51e-1)" "unprognostic (3.24e-3)" "unprognostic (2.00e-2)" "unprognostic (1.30e-1)" "unprognostic (9.17e-2)" "unprognostic (1.67e-1)" "unprognostic (5.96e-2)" "unprognostic (1.42e-2)" "unprognostic (6.85e-3)" "unprognostic (1.25e-1)" "unprognostic (5.34e-2)" "unprognostic (1.59e-1)" "unprognostic (4.08e-2)" "unprognostic (3.74e-1)" "unprognostic (2.73e-1)" "unprognostic (1.77e-1)" "unprognostic (1.15e-3)" "unprognostic (7.79e-2)" MYL6 "ESMLC, MLC1SM, MLC3NM" ENSG00000092841 "Myosin light chain 6" P60660 12 56158346-56163496 "Plasma proteins, Predicted intracellular proteins" "Motor protein, Muscle protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Decidual stromal cells: 6126.5;Esophageal apical cells: 7143.9;Esophageal suprabasal cells: 4394.7;Megakaryocytes: 10292.4;Platelets: 6269.6;Smooth muscle cells: 5059.4" "Cell type enhanced" "Detected in all" "vascular associated smooth muscle cell: 729.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Smooth muscle cells, Lung - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "HPA046859, HPA063034" Approved NA NA 67000000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 44: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 62: Smooth muscle cells - Muscle contraction" 58 "HPA046859: , HPA063034: " "unprognostic (8.19e-2)" "unprognostic (1.21e-1)" "unprognostic (1.01e-2)" "unprognostic (4.16e-1)" "unprognostic (1.69e-2)" "unprognostic (1.17e-1)" "unprognostic (1.46e-1)" "unprognostic (3.84e-1)" "unprognostic (4.65e-2)" "unprognostic (1.57e-2)" "unprognostic (1.66e-3)" "unprognostic (4.28e-2)" "unprognostic (1.08e-1)" "unprognostic (1.79e-2)" "unprognostic (2.02e-3)" "unprognostic (1.56e-1)" "unprognostic (2.13e-2)" "unprognostic (1.12e-1)" "unprognostic (2.53e-3)" "unprognostic (1.03e-1)" "unprognostic (2.73e-1)" "unprognostic (2.65e-1)" "unprognostic (8.79e-2)" "unprognostic (2.54e-1)" "unprognostic (2.46e-1)" "unprognostic (1.86e-1)" "unprognostic (6.89e-2)" "unprognostic (1.84e-3)" "unprognostic (2.31e-1)" "unprognostic (2.94e-1)" "unprognostic (1.82e-1)" MYL6B MLC1SA ENSG00000196465 "Myosin light chain 6B" P14649 12 56152256-56159647 "Plasma proteins, Predicted intracellular proteins" "Motor protein, Muscle protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 639.5;tongue: 611.1" "Cell type enriched" "Detected in all" 6 "Late spermatids: 2215.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 30.4" "Group enriched" "Detected in all" 5 "B-cells: 10.6;dendritic cells: 30.4;T-cells: 19.5" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Heart muscle - Cardiomyocytes, Minor Salivary Gland - Endothelial cells, Skeletal muscle - Skeletal myocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038887, HPA046859, HPA063034" Enhanced NA NA 13000000 "Cluster 13: Non-specific - Mitochondria" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 51: Neurons - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 27 "HPA038887: , HPA046859: , HPA063034: " "unprognostic (1.78e-1)" "unprognostic (2.50e-2)" "unprognostic (1.13e-2)" "unprognostic (2.94e-1)" "unprognostic (6.17e-3)" "unprognostic (5.75e-3)" "unprognostic (8.79e-2)" "unprognostic (9.27e-2)" "unprognostic (4.99e-2)" "unprognostic (3.92e-2)" "unprognostic (2.66e-2)" "unprognostic (2.39e-1)" "unprognostic (1.34e-1)" "validated prognostic unfavorable (6.71e-6)" "validated prognostic unfavorable (7.76e-7)" "unprognostic (2.23e-3)" "unprognostic (1.22e-2)" "unprognostic (3.48e-2)" "unprognostic (3.44e-1)" "unprognostic (9.28e-2)" "unprognostic (1.76e-1)" "unprognostic (2.18e-2)" "unprognostic (2.70e-3)" "unprognostic (5.87e-2)" "unprognostic (5.05e-2)" "unprognostic (2.94e-3)" "unprognostic (1.16e-1)" "unprognostic (2.38e-3)" "unprognostic (4.29e-2)" "unprognostic (2.39e-1)" "unprognostic (1.92e-1)" MYL7 "MYL2A, MYLC2A" ENSG00000106631 "Myosin light chain 7" Q01449 7 44138864-44141332 "Predicted intracellular proteins" "Motor protein, Muscle protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 853 "heart muscle: 22266.8" "Group enriched" "Detected in some" 5 "Breast myoepithelial cells: 82.7;Cardiomyocytes: 56.9" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in some" 7 "Testicular Germ Cell Tumor (TCGA): 17.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "testis cancer: 43.8" "Heart muscle - Cardiomyocytes" "Not detected" "Not detected" "HPA013331, CAB033884, HPA039262" Enhanced NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 5 "CAB033884: , HPA013331: , HPA039262: " "unprognostic (1.06e-2)" "unprognostic (3.81e-1)" "unprognostic (1.95e-1)" "unprognostic (8.23e-2)" "unprognostic (3.68e-1)" MYL9 "LC20, MLC2, MRLC1, MYRL2" ENSG00000101335 "Myosin light chain 9" P24844 20 36541497-36551447 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Motor protein, Muscle protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 7663.2;intestine: 7656.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 983.3;Breast myoepithelial cells: 2811.5;Decidual stromal cells: 3124.1;Hepatic stellate cells: 2013.9;Megakaryocytes: 1699.9;Pericytes: 1478.1;Peritubular myoid cells: 1667.8;Platelets: 2067.6;Salivary myoepithelial cells: 1061.5;Smooth muscle cells: 6679.7;Vascular smooth muscle cells: 4662.5" "Cell type enriched" "Detected in some" 4 "vascular associated smooth muscle cell: 1610.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 2.2;neutrophil: 1.9" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in all" "Bile duct cancer: 498.8" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Colon - Smooth muscle cells, Heart muscle - Cardiomyocytes, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Smooth muscle cells, Minor Salivary Gland - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Skin - Smooth muscle cells, Spleen - Fibroblasts_1, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 101.1" "HPA039262, HPA045244, HPA059197" Supported NA NA 24000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 17 "HPA039262: , HPA045244: , HPA059197: " "unprognostic (2.83e-2)" "unprognostic (2.51e-2)" "unprognostic (2.95e-1)" "unprognostic (1.15e-1)" "unprognostic (2.67e-3)" "unprognostic (9.55e-2)" "unprognostic (1.37e-2)" "potential prognostic unfavorable (3.15e-5)" "unprognostic (2.06e-2)" "unprognostic (2.62e-2)" "unprognostic (1.12e-1)" "unprognostic (6.95e-2)" "unprognostic (3.17e-2)" "unprognostic (1.69e-1)" "unprognostic (7.26e-2)" "unprognostic (1.34e-1)" "unprognostic (1.13e-1)" "unprognostic (1.15e-2)" "unprognostic (3.14e-3)" "unprognostic (2.66e-1)" "unprognostic (1.26e-3)" "unprognostic (1.19e-1)" "unprognostic (4.36e-2)" "unprognostic (3.03e-2)" "unprognostic (3.37e-2)" "unprognostic (3.41e-2)" "unprognostic (1.95e-1)" "unprognostic (1.69e-2)" "unprognostic (1.40e-1)" "unprognostic (2.06e-1)" "unprognostic (1.69e-1)" MYLIP "IDOL, MIR" ENSG00000007944 "Myosin regulatory light chain interacting protein" Q8WY64 6 16129086-16148248 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 568.6;Syncytiotrophoblasts: 671.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 40 "potential prognostic favorable (6.06e-4)" "unprognostic (6.82e-2)" "unprognostic (2.67e-1)" "unprognostic (7.62e-2)" "unprognostic (4.75e-2)" "unprognostic (1.46e-1)" "unprognostic (9.51e-2)" "unprognostic (1.51e-1)" "unprognostic (3.30e-2)" "unprognostic (7.07e-2)" "validated prognostic favorable (6.39e-10)" "validated prognostic favorable (1.44e-6)" "unprognostic (5.51e-2)" "unprognostic (1.29e-2)" "unprognostic (4.70e-1)" "potential prognostic favorable (5.65e-5)" "unprognostic (1.74e-1)" "unprognostic (6.19e-3)" "potential prognostic favorable (6.41e-4)" "unprognostic (2.53e-2)" "unprognostic (1.30e-2)" "unprognostic (1.72e-2)" "potential prognostic favorable (1.62e-4)" "unprognostic (3.73e-2)" "unprognostic (1.57e-1)" "unprognostic (3.55e-2)" "unprognostic (3.55e-2)" "unprognostic (1.10e-2)" "unprognostic (5.04e-2)" "unprognostic (5.25e-1)" "unprognostic (8.93e-2)" MYLK "KRP, MLCK, MLCK1, MLCK108, MLCK210, MYLK-L, MYLK1, smMLCK, Telokin" ENSG00000065534 "Myosin light chain kinase" Q15746 3 123610049-123884332 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Actin-binding, Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 1572.0;smooth muscle: 1933.2" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 2281.9;Hepatic stellate cells: 645.5;Megakaryocytes: 537.8;Peritubular myoid cells: 652.1;Platelets: 660.1;Salivary myoepithelial cells: 1108.7;Smooth muscle cells: 5303.5;Vascular smooth muscle cells: 738.5" "Cell type enhanced" "Detected in all" "astrocyte: 141.2;vascular associated smooth muscle cell: 308.4" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 232.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.7;neutrophil: 3.5" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in all" "Brain cancer: 92.9" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Breast - Breast myoepithelial cells, Colon - Smooth muscle cells, Heart muscle - Smooth muscle cells, Kidney - Fibroblasts, Minor Salivary Gland - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Spleen - Fibroblasts_1, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020789, HPA031677, HPA048055" Enhanced Enhanced "Plasma membrane,Actin filaments" NA NA 2300000 "Cluster 21: Neutrophils - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 30: White matter - Myelination" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 4 "Actin filaments" "Plasma membrane" "CAB020789: , HPA031677: , HPA048055: " "unprognostic (3.26e-3)" "unprognostic (5.13e-2)" "unprognostic (1.06e-1)" "unprognostic (3.17e-2)" "unprognostic (5.76e-2)" "unprognostic (3.12e-2)" "unprognostic (1.31e-1)" "unprognostic (1.58e-1)" "unprognostic (4.12e-2)" "unprognostic (2.72e-3)" "potential prognostic favorable (2.06e-6)" "unprognostic (1.38e-2)" "unprognostic (1.09e-3)" "unprognostic (4.40e-2)" "unprognostic (1.15e-3)" "unprognostic (9.43e-2)" "unprognostic (2.01e-1)" "unprognostic (2.62e-3)" "unprognostic (3.78e-2)" "unprognostic (1.07e-2)" "unprognostic (8.72e-3)" "unprognostic (6.68e-2)" "unprognostic (5.13e-2)" "unprognostic (1.27e-1)" "unprognostic (5.89e-3)" "unprognostic (2.26e-2)" "unprognostic (1.38e-1)" "unprognostic (1.94e-2)" "unprognostic (2.92e-1)" "unprognostic (8.09e-2)" "unprognostic (7.18e-2)" MYLK2 "KMLC, MLCK2, skMLCK" ENSG00000101306 "Myosin light chain kinase 2" Q9H1R3 20 31819308-31834689 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "skeletal muscle: 686.1" "Cell type enriched" "Detected in some" 14 "Myonuclei: 194.7" "Cell type enriched" "Detected in some" 10 "endothelial cell: 33.2" "Cancer enhanced" "Detected in single" "Glioblastoma Multiforme (TCGA): 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA059704, HPA059890" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 38: Non-specific - Transcription" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 14 "Endoplasmic reticulum" "HPA059704: , HPA059890: " "unprognostic (1.07e-2)" "unprognostic (1.68e-3)" "unprognostic (2.14e-2)" MYLK3 "caMLCK, MLCK" ENSG00000140795 "Myosin light chain kinase 3" Q32MK0 16 46702282-46790407 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "heart muscle: 96.8;skeletal muscle: 43.4;tongue: 67.7" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 347.0;Endometrial ciliated cells: 97.8;Ependymal cells: 281.2;Myonuclei: 210.4;Podocytes: 72.3;Sertoli cells: 112.4;Thymic myoid cells: 526.2" "Cell type enriched" "Detected in many" 9 "ependymal cell: 340.1" "Cancer enhanced" "Detected in single" "Uterine Corpus Endometrial Carcinoma (TCGA): 1.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Leukemia: 5.4;testis cancer: 3.2" "Heart muscle - Cardiomyocytes, Kidney - Podocytes, Lung - Respiratory ciliated cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes" "Group enriched" "Detected in some" 7 "cerebral cortex: 9.6;hippocampal formation: 5.1" "Region enriched" "Detected in single" 5 "hippocampal formation: 4.6" HPA073447 Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 41: Striated muscle - Muscle contraction" "Cluster 46: Brainstem - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 1 Nucleoplasm "Vesicles, Cytosol" "HPA073447: " "unprognostic (1.12e-2)" "unprognostic (1.48e-1)" MYLK4 SgK085 ENSG00000145949 "Myosin light chain kinase family member 4" Q86YV6 6 2663629-2770330 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 17 "skeletal muscle: 27.0;tongue: 66.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 78.8;Epicardial cells: 36.4;Gonadotrophs: 32.9;Hematopoietic stem cells: 35.9;Myonuclei: 165.2" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Bladder Urothelial Carcinoma (TCGA): 3.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA015860 Uncertain Approved "Nucleoli,Golgi apparatus,Vesicles" NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 1: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 12 "Golgi apparatus" "Nucleoli, Vesicles" "HPA015860: " "unprognostic (6.98e-3)" "unprognostic (2.90e-1)" "unprognostic (2.26e-2)" "unprognostic (8.89e-3)" "potential prognostic favorable (2.53e-5)" "unprognostic (3.90e-3)" "unprognostic (2.84e-2)" "unprognostic (1.45e-1)" "unprognostic (2.25e-2)" MYMK "MYOMAKER, TMEM226, TMEM8C" ENSG00000187616 "Myomaker, myoblast fusion factor" A6NI61 9 133514586-133528612 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Myogenesis "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Podocytes: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 43 "Sarcoma: 7.9" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA051846, HPA055785" Uncertain NA NA "Cluster 11: White matter - Signal transduction" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 105: Non-specific - Mixed function" "HPA051846: , HPA055785: " MYMX MINION ENSG00000262179 "Myomixer, myoblast fusion factor" A0A1B0GTQ4 6 44216926-44218234 "Disease related genes, Predicted intracellular proteins" Myogenesis "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Group enriched" "Detected in some" 4 "adipose tissue: 7.1;blood vessel: 1.9;breast: 6.7;pancreas: 5.2;stomach 1: 2.2" "Cell type enhanced" "Detected in some" "Conjunctival goblet cells: 1.9;Extravillous trophoblasts: 2.3;Gastric chief cells: 3.3;Kupffer cells: 4.1;Parietal cells: 5.3;pDCs: 10.9;Peritubular myoid cells: 1.8;Respiratory ionocytes: 5.1;Salivary basal cells: 1.4;Salivary duct cells: 2.3" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Kidney Chromophobe (TCGA): 3.4;Testicular Germ Cell Tumor (TCGA): 4.5" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 107 "plasmacytoid DC: 10.6" "Lineage enriched" "Detected in single" 107 "dendritic cells: 10.6" "Cancer enhanced" "Detected in some" "Rhabdoid: 5.8;Sarcoma: 14.5" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Skeletal muscle - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA051451 Supported Approved Vesicles,Mitochondria,Cytosol NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 70: Non-specific - Protein processing" "Cluster 24: Non-specific - Unknown function" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" Vesicles "Mitochondria, Cytosol" "HPA051451: " "unprognostic (6.27e-2)" "unprognostic (1.65e-1)" MYNN "SBBIZ1, ZBTB31, ZNF902" ENSG00000085274 Myoneurin Q9NPC7 3 169773396-169789716 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045149 Approved Supported Nucleoplasm NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 40: Non-specific - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 12 Nucleoplasm "HPA045149: " "unprognostic (1.18e-1)" "unprognostic (7.66e-2)" "unprognostic (6.57e-2)" "unprognostic (1.14e-1)" "unprognostic (6.31e-2)" "unprognostic (4.30e-2)" "unprognostic (1.04e-1)" "unprognostic (1.73e-2)" "unprognostic (2.88e-1)" "unprognostic (2.83e-1)" "potential prognostic favorable (1.46e-4)" "unprognostic (2.12e-2)" "unprognostic (1.43e-1)" "unprognostic (4.34e-2)" "unprognostic (1.14e-1)" "unprognostic (1.76e-1)" "unprognostic (2.05e-2)" "unprognostic (1.67e-3)" "unprognostic (4.12e-2)" "unprognostic (1.45e-1)" "potential prognostic unfavorable (1.41e-4)" "unprognostic (6.24e-3)" "potential prognostic unfavorable (4.29e-4)" "unprognostic (5.64e-2)" "unprognostic (3.29e-2)" "unprognostic (4.15e-2)" "unprognostic (6.16e-2)" "unprognostic (6.92e-2)" "unprognostic (1.78e-1)" "unprognostic (2.67e-3)" "unprognostic (3.93e-1)" MYO10 "KIAA0799, MyoX" ENSG00000145555 "Myosin X" Q9HD67 5 16661907-16936288 "Plasma proteins, Predicted intracellular proteins" Transport "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 638.1;Endometrial luminal cells: 973.4;Granulosa cells: 665.0;Melanocytes: 829.4;Renal collecting duct intercalated cells: 607.5;Sertoli cells: 605.9" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 379.0;endothelial cell: 689.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "non-classical monocyte: 2.6" "Lineage enriched" "Detected in single" 5 "monocytes: 2.6" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Spleen - Endothelial cells, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015224, HPA024223" Enhanced Supported "Nucleoli rim,Plasma membrane,Cytosol" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 36: Brain & Liver - Signaling" "Cluster 53: Neurons - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 11 "Plasma membrane, Cytosol" "Nucleoli rim" "CAB015224: , HPA024223: " "potential prognostic unfavorable (2.05e-4)" "unprognostic (7.98e-2)" "unprognostic (7.87e-2)" "unprognostic (1.98e-3)" "unprognostic (3.24e-1)" "unprognostic (9.87e-2)" "unprognostic (3.28e-2)" "unprognostic (7.08e-2)" "unprognostic (1.15e-1)" "unprognostic (1.40e-2)" "potential prognostic favorable (6.33e-4)" "unprognostic (1.88e-3)" "unprognostic (2.98e-1)" "unprognostic (5.56e-2)" "potential prognostic favorable (3.92e-4)" "unprognostic (2.86e-1)" "unprognostic (1.03e-3)" "unprognostic (3.87e-2)" "unprognostic (6.84e-2)" "unprognostic (3.68e-1)" "unprognostic (1.57e-1)" "unprognostic (1.36e-1)" "unprognostic (6.84e-2)" "unprognostic (1.05e-1)" "unprognostic (5.33e-2)" "unprognostic (3.94e-2)" "unprognostic (8.68e-3)" "unprognostic (1.06e-1)" "unprognostic (1.55e-1)" "unprognostic (1.38e-2)" "unprognostic (9.05e-2)" MYO15A "DFNB3, MYO15" ENSG00000091536 "Myosin XVA" Q9UKN7 17 18108756-18179802 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Hearing "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "pituitary gland: 40.5" "Cell type enhanced" "Detected in many" "Early spermatids: 115.9;Gonadotrophs: 39.7;Lactotrophs: 88.9;Late spermatids: 95.5;Somatotrophs: 545.6;Thyrotrophs: 201.5" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "basophil: 1.4" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.4" "Cancer enhanced" "Detected in single" "lung cancer: 1.3" "Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" HPA078501 Enhanced NA NA "Cluster 20: Pituitary gland - Hormone signaling" "Cluster 24: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 2 "HPA078501: " "unprognostic (1.96e-1)" "unprognostic (1.68e-1)" "unprognostic (3.48e-3)" MYO15B MYO15BP ENSG00000266714 "Myosin XVB" 17 75587800-75626849 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "intestine: 201.7" "Cell type enhanced" "Detected in many" "Colonocytes: 295.8;Enterocytes: 426.9;Tuft cells: 368.9" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 113.2;ependymal cell: 111.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "colorectal cancer: 23.4;Gastric cancer: 16.9" "Skin - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA022857, HPA023105" Approved Cytosol No No "Cluster 77: Intestine - Digestion" "Cluster 11: White matter - Signal transduction" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 1 Cytosol "HPA022857: , HPA023105: " "unprognostic (3.26e-3)" "unprognostic (3.84e-2)" "unprognostic (3.38e-2)" "unprognostic (4.63e-2)" "unprognostic (7.51e-2)" "unprognostic (1.51e-1)" "unprognostic (1.21e-1)" "unprognostic (1.83e-1)" "unprognostic (1.14e-2)" "unprognostic (2.45e-1)" "unprognostic (3.69e-2)" "unprognostic (2.00e-2)" "unprognostic (2.25e-3)" "unprognostic (2.60e-3)" "unprognostic (1.44e-3)" "unprognostic (7.93e-2)" "unprognostic (4.26e-2)" "unprognostic (1.13e-1)" "unprognostic (2.66e-2)" "unprognostic (1.12e-1)" "unprognostic (1.90e-2)" "unprognostic (1.80e-2)" "unprognostic (2.81e-2)" "unprognostic (6.07e-2)" "unprognostic (1.57e-1)" "unprognostic (3.99e-2)" "unprognostic (2.15e-2)" "unprognostic (1.48e-1)" "unprognostic (1.09e-1)" "unprognostic (1.63e-1)" "unprognostic (7.15e-2)" MYO16 "KIAA0865, Myo16b, MYR8, NYAP3, PPP1R107" ENSG00000041515 "Myosin XVI" Q9Y6X6 13 108596152-109208005 "Predicted intracellular proteins" "Actin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.6;pituitary gland: 2.4" "Cell type enriched" "Detected in many" 7 "Pituicytes/FSCs: 2064.5" "Cell type enhanced" "Detected in all" "cerebellar inhibitory: 917.0;LAMP5-LHX6 and Chandelier: 1314.4" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 2.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Leukemia: 1.6" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Testis - Early spermatids" "Region enhanced" "Detected in all" "olfactory bulb: 72.6" "Low region specificity" "Detected in all" "HPA040110, HPA058769, HPA071948" Uncertain Approved Vesicles NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 51: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 2 Vesicles "HPA040110: , HPA058769: , HPA071948: " "unprognostic (1.99e-1)" "unprognostic (1.07e-1)" "unprognostic (6.37e-3)" "unprognostic (2.09e-1)" "unprognostic (1.27e-1)" "unprognostic (1.42e-1)" MYO18A "KIAA0216, MysPDZ, TIAF1" ENSG00000196535 "Myosin XVIIIA" Q92614 17 29071122-29180398 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 381.4;tongue: 115.5" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 239.1;Esophageal apical cells: 119.2;Myonuclei: 371.0;Tuft cells: 149.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019646 Supported NA NA 3100 "Cluster 24: Non-specific - Transcription" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 6: Non-specific - Immune response" "Cluster 27: Breast cancer - Unknown function" "Cluster 55: Myocytes - Oxidative muscle function" 22 "HPA019646: " "unprognostic (4.78e-2)" "unprognostic (5.46e-2)" "unprognostic (6.27e-2)" "unprognostic (2.14e-3)" "unprognostic (8.77e-2)" "unprognostic (2.23e-1)" "unprognostic (1.58e-1)" "unprognostic (1.58e-3)" "unprognostic (2.91e-1)" "unprognostic (6.83e-2)" "validated prognostic favorable (5.71e-7)" "validated prognostic favorable (1.70e-4)" "unprognostic (1.05e-1)" "unprognostic (3.27e-1)" "unprognostic (1.94e-2)" "unprognostic (8.69e-2)" "unprognostic (2.71e-1)" "unprognostic (4.67e-2)" "unprognostic (2.86e-1)" "unprognostic (3.83e-2)" "unprognostic (2.38e-1)" "unprognostic (1.31e-1)" "unprognostic (1.62e-3)" "unprognostic (1.06e-1)" "unprognostic (1.13e-2)" "unprognostic (7.22e-3)" "unprognostic (3.02e-1)" "unprognostic (6.07e-2)" "unprognostic (2.32e-1)" "unprognostic (4.13e-3)" "unprognostic (2.35e-1)" MYO18B BK125H2.1 ENSG00000133454 "Myosin XVIIIB" Q8IUG5 22 25742144-26031045 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 114.3;skeletal muscle: 251.6;tongue: 51.9" "Group enriched" "Detected in many" 4 "Cardiomyocytes: 732.2;Myonuclei: 1232.2;Myosatellite cells: 414.9;Thymic myoid cells: 333.1" "Cell type enhanced" "Detected in many" "thalamic excitatory: 15.2" "Cancer enhanced" "Detected in single" "Head and Neck Squamous Cell Carcinoma (TCGA): 1.8" "Group enriched" "Detected in some" 4 "midbrain: 1.8;thalamus: 5.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 11.3;Sarcoma: 6.8" "Heart muscle - Cardiomyocytes, Skin - Sebaceous gland cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA000953 Uncertain Supported Nucleoplasm,Centrosome NA NA "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 46: Skeletal myocytes - Muscle structure & formation" "Nucleoplasm, Centrosome" "HPA000953: " "unprognostic (1.47e-1)" "unprognostic (5.87e-3)" "unprognostic (1.00e-1)" MYO19 "FLJ22865, MYOHD1" ENSG00000278259 "Myosin XIX" Q96H55 17 36495636-36543435 "Predicted intracellular proteins" "Actin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 44.9;Bergmann glia: 41.1;Brain excitatory neurons: 33.8;Brain inhibitory neurons: 36.6;Choroid plexus epithelial cells: 72.3;Distal convoluted tubule cells: 79.3;Early spermatids: 54.7;Ependymal cells: 42.4;Loop of henle epithelial cells: 65.5;Microglia: 37.8;Oligodendrocyte progenitor cells: 31.7;Oligodendrocytes: 38.9;Papillary tip epithelial cells: 30.6;Proximal tubule cells: 49.0;Renal collecting duct intercalated cells: 119.5;Renal collecting duct principal cells: 40.0;Renal connecting tubule cells: 61.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021415, HPA059715" Approved Enhanced Mitochondria,Cytosol NA Yes "Cluster 24: Non-specific - Transcription" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 102: Non-specific - Mixed function" 4 Mitochondria Cytosol "HPA021415: , HPA059715: " "unprognostic (5.21e-2)" "unprognostic (3.45e-2)" "unprognostic (2.54e-1)" "unprognostic (1.95e-1)" "unprognostic (4.61e-2)" "unprognostic (1.93e-2)" "unprognostic (1.88e-1)" "unprognostic (4.78e-2)" "unprognostic (3.42e-2)" "unprognostic (2.71e-2)" "unprognostic (1.67e-3)" "unprognostic (2.57e-1)" "potential prognostic unfavorable (1.97e-5)" "unprognostic (5.63e-3)" "validated prognostic unfavorable (2.26e-5)" "validated prognostic unfavorable (1.21e-4)" "unprognostic (1.68e-1)" "unprognostic (1.09e-1)" "unprognostic (3.85e-1)" "potential prognostic unfavorable (5.02e-4)" "unprognostic (5.05e-2)" "unprognostic (1.53e-3)" "potential prognostic favorable (8.04e-4)" "unprognostic (1.91e-2)" "unprognostic (1.99e-2)" "unprognostic (3.13e-1)" "unprognostic (5.44e-2)" "unprognostic (8.93e-2)" MYO1A "BBMI, DFNA48, MYHL" ENSG00000166866 "Myosin IA" Q9UBC5 12 57028517-57051198 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "intestine: 310.6" "Cell type enriched" "Detected in some" 5 "Enterocytes: 367.6" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 1.4;oligodendrocyte: 1.3" "Group enriched" "Detected in some" 15 "Colon Adenocarcinoma (TCGA): 26.1;Pancreatic Adenocarcinoma (TCGA): 7.1;Rectum Adenocarcinoma (TCGA): 25.8;Stomach Adenocarcinoma (TCGA): 15.6" "Region enhanced" "Detected in many" "white matter: 16.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 10.6;colorectal cancer: 18.5;Gastric cancer: 10.3" "Colon - Colon enterocytes, Pancreas - Ductal cells, Pituitary gland - Gonadotropes, Stomach - Gastric mucous cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA053490 Enhanced Approved Nucleoplasm NA NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 22: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 1: Enterocytes - Absorption and Digestion" 1 Nucleoplasm "HPA053490: " "unprognostic (3.18e-3)" "unprognostic (3.04e-1)" "unprognostic (9.28e-2)" "unprognostic (1.64e-3)" "unprognostic (8.51e-2)" "unprognostic (1.13e-1)" "unprognostic (3.64e-2)" "unprognostic (9.30e-3)" "unprognostic (1.54e-1)" "unprognostic (2.41e-1)" MYO1B myr1 ENSG00000128641 "Myosin IB" O43795 2 191245185-191425389 "Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 238.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 592.5;Alveolar cells type 2: 394.4;Hepatocytes: 807.1;Pancreatic duct cells: 354.7;Pericytes: 639.3;Podocytes: 772.0;Renal connecting tubule cells: 492.2;Tuft cells: 461.1" "Group enriched" "Detected in many" 5 "pericyte: 1572.8;vascular associated smooth muscle cell: 673.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Liver - Hepatocytes, Skeletal muscle - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013607, HPA060144" Approved Enhanced "Plasma membrane" NA NA 13000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 38: Sub-cortical - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 110: Mural cells - ECM organization" 44 "Plasma membrane" "HPA013607: , HPA060144: " "unprognostic (9.53e-2)" "unprognostic (1.72e-2)" "unprognostic (2.32e-1)" "unprognostic (1.54e-3)" "unprognostic (1.06e-1)" "unprognostic (8.94e-2)" "unprognostic (4.13e-1)" "unprognostic (9.79e-2)" "potential prognostic unfavorable (4.45e-4)" "unprognostic (1.65e-1)" "unprognostic (1.16e-3)" "unprognostic (1.49e-3)" "potential prognostic unfavorable (6.30e-4)" "unprognostic (4.48e-2)" "potential prognostic favorable (1.97e-7)" "unprognostic (1.79e-1)" "potential prognostic unfavorable (9.87e-4)" "unprognostic (5.17e-3)" "unprognostic (1.04e-2)" "unprognostic (6.00e-2)" "unprognostic (6.61e-2)" "unprognostic (2.51e-1)" "unprognostic (2.01e-2)" "unprognostic (1.16e-1)" "unprognostic (1.30e-1)" "unprognostic (1.52e-1)" "unprognostic (3.19e-3)" "unprognostic (7.46e-2)" "unprognostic (2.68e-1)" "unprognostic (7.69e-2)" "unprognostic (3.17e-1)" MYO1C "MyoIC, myr2, NMI" ENSG00000197879 "Myosin IC" O00159 17 1464186-1492686 "Predicted intracellular proteins, Transporters" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 194.1;Alveolar cells type 1: 295.3" "Cell type enhanced" "Detected in many" "endothelial cell: 60.5;pericyte: 74.7;vascular associated smooth muscle cell: 86.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 449.8" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Prostate - Smooth muscle cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001768, HPA005924, CAB037023" Enhanced Enhanced "Nuclear bodies,Plasma membrane" NA NA 72000 "Cluster 14: Non-specific - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 47: Endothelial cells - Vasculature" "Cluster 42: Non-specific - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 50 "Nuclear bodies, Plasma membrane" "CAB037023: , HPA001768: , HPA005924: " "unprognostic (6.60e-2)" "unprognostic (1.13e-1)" "unprognostic (4.56e-1)" "unprognostic (3.80e-3)" "unprognostic (1.20e-1)" "unprognostic (9.54e-2)" "unprognostic (1.06e-2)" "unprognostic (1.06e-2)" "unprognostic (4.00e-2)" "unprognostic (3.74e-2)" "potential prognostic favorable (6.17e-6)" "unprognostic (8.69e-3)" "unprognostic (1.47e-1)" "unprognostic (2.29e-1)" "unprognostic (1.13e-1)" "unprognostic (1.26e-2)" "unprognostic (1.93e-1)" "unprognostic (5.11e-3)" "unprognostic (9.66e-2)" "unprognostic (2.99e-2)" "unprognostic (2.60e-1)" "unprognostic (8.04e-2)" "unprognostic (3.08e-1)" "unprognostic (3.90e-2)" "unprognostic (2.00e-1)" "unprognostic (2.87e-2)" "unprognostic (6.65e-2)" "unprognostic (1.83e-1)" "unprognostic (1.59e-1)" "unprognostic (7.80e-2)" "unprognostic (5.18e-2)" MYO1D "KIAA0727, myr4, PPP1R108" ENSG00000176658 "Myosin ID" O94832 17 32492522-32877177 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "blood vessel: 223.6;intestine: 104.3" "Cell type enhanced" "Detected in all" "Colonocytes: 1137.9;Goblet cells: 950.3;Podocytes: 1064.9" "Cell type enhanced" "Detected in all" "oligodendrocyte: 957.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054744 Approved Approved Cytosol NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 11: White matter - Signal transduction" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 38 Cytosol "HPA054744: " "unprognostic (1.92e-1)" "unprognostic (9.19e-3)" "unprognostic (7.77e-2)" "unprognostic (7.36e-3)" "unprognostic (4.02e-2)" "unprognostic (1.29e-1)" "unprognostic (5.40e-2)" "unprognostic (1.68e-1)" "unprognostic (1.59e-1)" "unprognostic (1.08e-2)" "potential prognostic favorable (4.73e-6)" "unprognostic (4.16e-3)" "unprognostic (4.24e-2)" "unprognostic (5.42e-1)" "unprognostic (1.35e-1)" "unprognostic (1.58e-1)" "unprognostic (1.07e-1)" "unprognostic (2.10e-3)" "unprognostic (2.93e-2)" "unprognostic (9.30e-3)" "unprognostic (3.01e-3)" "unprognostic (1.13e-1)" "unprognostic (4.36e-2)" "unprognostic (2.67e-1)" "unprognostic (2.40e-2)" "unprognostic (1.13e-1)" "unprognostic (1.71e-1)" "unprognostic (2.54e-1)" "unprognostic (2.27e-1)" "unprognostic (1.95e-1)" "unprognostic (6.21e-2)" MYO1E "HuncM-IC, MGC104638, MYO1C" ENSG00000157483 "Myosin IE" Q12965 15 59132434-59372871 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 1211.0;Endometrial glandular cells: 1107.5;Podocytes: 1858.6;Urothelial cells: 1224.4" "Cell type enhanced" "Detected in all" "endothelial cell: 509.9;ependymal cell: 373.1;oligodendrocyte: 551.1;vascular associated smooth muscle cell: 321.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 23.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003003, HPA023886" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 5600 "Cluster 13: Non-specific - Mitochondria" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 51: Secretory epithelial cells - Mixed function" 38 "Nucleoplasm, Plasma membrane" Cytosol "HPA003003: , HPA023886: " "unprognostic (4.09e-1)" "unprognostic (7.97e-2)" "unprognostic (3.24e-1)" "unprognostic (4.35e-1)" "unprognostic (8.22e-2)" "unprognostic (1.93e-1)" "unprognostic (1.39e-1)" "unprognostic (4.44e-3)" "unprognostic (1.99e-1)" "unprognostic (2.46e-2)" "unprognostic (4.91e-3)" "unprognostic (5.91e-2)" "unprognostic (3.07e-1)" "unprognostic (1.78e-2)" "unprognostic (1.25e-1)" "potential prognostic unfavorable (2.92e-7)" "unprognostic (7.96e-2)" "unprognostic (9.57e-2)" "unprognostic (5.72e-2)" "unprognostic (6.17e-2)" "unprognostic (2.23e-2)" "potential prognostic unfavorable (8.75e-5)" "unprognostic (6.54e-3)" "unprognostic (1.96e-1)" "unprognostic (4.47e-1)" "unprognostic (1.69e-1)" "unprognostic (9.62e-2)" "unprognostic (1.60e-1)" "unprognostic (2.17e-1)" "unprognostic (1.83e-1)" "unprognostic (1.69e-2)" MYO1F ENSG00000142347 "Myosin IF" O00160 19 8520778-8577577 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 90.7;lung: 29.3;lymphoid tissue: 93.0" "Cell type enhanced" "Detected in many" "cDC: 227.4;Kupffer cells: 546.3;Macrophages: 245.6;Microglia: 301.5;Monocyte progenitors: 375.0;monocytes: 480.7;Neutrophil progenitors: 872.9;Neutrophils: 2677.0;NK-cells: 368.3" "Group enriched" "Detected in many" 27 "central nervous system macrophage: 374.7;leukocyte: 391.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 263.8" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in some" 8 "Leukemia: 51.2" "Adipose subcutaneous - Macrophages, Adrenal gland - Macrophages, Lung - Neutrophils_2, Minor Salivary Gland - Macrophages, Spleen - Neutrophils_2, Thyroid gland - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA055242, HPA056036" Enhanced Enhanced Cytosol NA NA 12000 "Cluster 28: Neutrophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 13 Cytosol "HPA055242: , HPA056036: " "unprognostic (3.28e-2)" "unprognostic (5.37e-2)" "unprognostic (1.08e-2)" "unprognostic (1.08e-2)" "unprognostic (5.46e-2)" "unprognostic (1.21e-1)" "unprognostic (2.70e-2)" "unprognostic (2.47e-1)" "unprognostic (2.94e-3)" "unprognostic (4.00e-1)" "unprognostic (8.79e-2)" "unprognostic (9.37e-2)" "unprognostic (4.09e-3)" "unprognostic (1.45e-1)" "unprognostic (2.33e-2)" "unprognostic (3.33e-3)" "unprognostic (4.87e-2)" "unprognostic (8.04e-2)" "unprognostic (2.28e-1)" "unprognostic (1.00e-1)" "unprognostic (3.08e-1)" "unprognostic (1.67e-2)" "unprognostic (4.26e-3)" "unprognostic (1.97e-1)" "unprognostic (2.47e-2)" "unprognostic (1.88e-2)" "unprognostic (9.62e-3)" "unprognostic (2.58e-1)" "unprognostic (4.33e-3)" "unprognostic (4.07e-2)" "unprognostic (6.37e-2)" MYO1G HA-2 ENSG00000136286 "Myosin IG" B0I1T2 7 44962662-44979088 "Predicted intracellular proteins" "Adaptive immunity, Immunity" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 41.1;lymphoid tissue: 25.3" "Cell type enhanced" "Detected in some" "B-cells: 41.3;cDC: 44.2;Innate lymphoid cells: 26.7;Macrophages: 29.7;Megakaryocyte-Erythroid progenitors: 24.1;Monocyte progenitors: 98.6;monocytes: 154.3;Neutrophil progenitors: 47.6;Neutrophils: 30.6;NK-cells: 69.0;T-cells: 60.9;Thymocytes: 53.4" "Cell type enriched" "Detected in some" 49 "leukocyte: 72.2" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 16.5" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 15 "Leukemia: 88.2;lymphoma: 96.1" "Adipose subcutaneous - T-cells, Breast - T-cells, Kidney - T-cells, Prostate - T-cells, Spleen - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA021252 Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA 37000 "Cluster 33: Non-specific - ATP binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" "Plasma membrane" Nucleoplasm "HPA021252: " "unprognostic (3.21e-2)" "unprognostic (1.22e-1)" "unprognostic (2.80e-2)" "unprognostic (2.10e-3)" "unprognostic (2.21e-1)" "unprognostic (4.31e-1)" "unprognostic (2.97e-3)" "unprognostic (2.68e-1)" "potential prognostic favorable (5.46e-4)" "unprognostic (1.93e-3)" "unprognostic (2.31e-1)" "unprognostic (1.45e-1)" "unprognostic (3.70e-2)" "unprognostic (2.24e-1)" "unprognostic (8.57e-2)" "unprognostic (8.25e-3)" "unprognostic (2.75e-1)" "unprognostic (8.48e-2)" "unprognostic (4.98e-2)" "unprognostic (2.82e-2)" "unprognostic (4.46e-3)" "unprognostic (8.50e-2)" "unprognostic (3.41e-2)" "unprognostic (9.33e-2)" "unprognostic (1.51e-1)" "unprognostic (2.01e-1)" "unprognostic (2.85e-3)" "unprognostic (1.90e-1)" MYO1H FLJ37587 ENSG00000174527 "Myosin IH" 12 109347900-109455523 "Human disease related genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "testis: 1.0" "Cell type enhanced" "Detected in many" "Adipocytes: 34.0;Cardiomyocytes: 38.2;Epicardial cells: 29.6;Fibro-adipogenic progenitors: 20.2" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 12.1" "Cancer enriched" "Detected in single" 11 "Kidney Chromophobe (TCGA): 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA039516 Uncertain NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "HPA039516: " "unprognostic (9.29e-2)" "unprognostic (3.08e-1)" MYO3A DFNB30 ENSG00000095777 "Myosin IIIA" Q8NEV4 10 25934229-26212532 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hearing, Sensory transduction, Vision" "Actin-binding, Kinase, Motor protein, Myosin, Serine/threonine-protein kinase, Transferase" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "retina: 14.3;testis: 5.2" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 136.6;Early spermatids: 249.7;Ependymal cells: 129.1;Gonadotrophs: 110.7;Late primary spermatocytes: 129.1;Late spermatids: 96.4;Müller glia: 475.7;Pancreatic islet cells: 263.1;Vascular smooth muscle cells: 75.5" "Group enriched" "Detected in many" 4 "ependymal cell: 122.2;medium spiny neuron: 99.2;midbrain-derived inhibitory: 61.9;vascular associated smooth muscle cell: 141.9" "Cancer enhanced" "Detected in some" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 3.5;Kidney Renal Clear Cell Carcinoma (TCGA): 3.1" "Region enhanced" "Detected in some" "basal ganglia: 3.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 3.5" "Adipose subcutaneous - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "HPA051893, HPA075413" Enhanced Supported "Plasma membrane,Actin filaments,Cytoplasmic bodies" No No "Cluster 42: Retina - Visual perception" "Cluster 33: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 1 "Actin filaments, Cytoplasmic bodies" "Plasma membrane" "HPA051893: , HPA075413: " "unprognostic (4.96e-2)" "unprognostic (9.57e-3)" "unprognostic (3.03e-2)" "potential prognostic favorable (1.73e-4)" "unprognostic (1.51e-2)" "unprognostic (9.28e-2)" "unprognostic (4.34e-2)" "potential prognostic unfavorable (8.57e-4)" "unprognostic (3.52e-2)" MYO3B ENSG00000071909 "Myosin IIIB" Q8WXR4 2 170178145-170655171 "Enzymes, Predicted intracellular proteins" "Hearing, Sensory transduction, Vision" "Actin-binding, Kinase, Motor protein, Myosin, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 13.3;kidney: 4.9;parathyroid gland: 8.3;retina: 5.4" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 1459.4;Distal convoluted tubule cells: 367.5;Epididymal principal cells: 246.3;Loop of henle epithelial cells: 318.9;Papillary tip epithelial cells: 436.1;Renal collecting duct intercalated cells: 176.7;Renal collecting duct principal cells: 465.7;Renal connecting tubule cells: 286.1;Rod photoreceptor cells: 759.1;Somatotrophs: 187.9" "Cell type enhanced" "Detected in many" "midbrain-derived inhibitory: 141.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lymphoma: 2.2" "Kidney - Ascending Loop of Henle cells, Pituitary gland - Somatotropes, Skin - Outer root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in some" 5 "basal ganglia: 5.2" "Region enhanced" "Detected in single" "olfactory bulb: 1.4" HPA045483 Approved NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 79: Photoreceptor cells - Phototransduction" 3 "HPA045483: " "unprognostic (1.95e-1)" "unprognostic (7.31e-3)" "unprognostic (3.46e-2)" "unprognostic (1.15e-1)" "unprognostic (6.21e-2)" "unprognostic (1.29e-1)" "unprognostic (1.80e-1)" "unprognostic (2.07e-1)" "unprognostic (1.38e-1)" MYO5A "GS1, MYH12, MYO5, MYR12" ENSG00000197535 "Myosin VA" Q9Y4I1 15 52307281-52529132 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 31.4;parathyroid gland: 36.7" "Cell type enhanced" "Detected in many" "Macrophages: 435.2;Melanocytes: 1050.7;Neutrophil progenitors: 389.4;Neutrophils: 432.7;Oligodendrocyte progenitor cells: 482.9;Oligodendrocytes: 579.7" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 57.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "skin cancer: 61.5" "Adipose subcutaneous - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001356 Enhanced Approved "Focal adhesion sites,Primary cilium,Centriolar satellite,Basal body,Cytosol,Calyx" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 42: Retina - Visual perception" "Cluster 34: Non-specific - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 13 "Focal adhesion sites, Centriolar satellite" "Primary cilium, Basal body, Cytosol, Calyx" "HPA001356: " "unprognostic (2.24e-2)" "unprognostic (2.64e-1)" "unprognostic (4.81e-1)" "unprognostic (1.89e-1)" "unprognostic (6.90e-2)" "unprognostic (2.95e-1)" "unprognostic (4.95e-2)" "unprognostic (2.40e-3)" "unprognostic (2.23e-2)" "unprognostic (1.21e-2)" "potential prognostic favorable (1.14e-4)" "unprognostic (5.19e-2)" "unprognostic (1.85e-1)" "unprognostic (2.87e-2)" "unprognostic (1.94e-1)" "unprognostic (1.79e-1)" "unprognostic (1.82e-3)" "unprognostic (1.48e-2)" "unprognostic (1.56e-1)" "unprognostic (4.77e-3)" "unprognostic (1.89e-3)" "unprognostic (8.83e-2)" "potential prognostic unfavorable (1.83e-4)" "unprognostic (3.00e-1)" "unprognostic (1.35e-1)" "unprognostic (7.09e-2)" "unprognostic (9.32e-2)" "unprognostic (2.25e-2)" "unprognostic (9.20e-2)" "unprognostic (7.33e-2)" "unprognostic (3.38e-2)" MYO5B KIAA1119 ENSG00000167306 "Myosin VB" Q9ULV0 18 49822789-50195164 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 58.3" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 584.1;Endometrial luminal cells: 340.2;Esophageal apical cells: 446.2;Ocular epithelial cells: 714.1;Salivary acinar cells: 666.2;Urothelial cells: 454.4" "Cell type enhanced" "Detected in many" "hippocampal dentate gyrus: 168.5;mammillary body: 375.0;MGE interneuron: 209.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Minor Salivary Gland - Minor salivary glandular cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA040593, HPA040902, HPA069773" Enhanced Approved "Plasma membrane" NA NA "Cluster 17: Intestine - Digestion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 51: Secretory epithelial cells - Mixed function" 14 "Plasma membrane" "HPA040593: , HPA040902: , HPA069773: " "unprognostic (1.72e-1)" "unprognostic (4.86e-1)" "unprognostic (2.09e-2)" "unprognostic (1.97e-1)" "unprognostic (1.33e-2)" "unprognostic (7.02e-2)" "unprognostic (2.86e-1)" "unprognostic (2.34e-1)" "unprognostic (6.39e-3)" "unprognostic (5.37e-3)" "potential prognostic favorable (2.87e-7)" "unprognostic (3.60e-2)" "potential prognostic favorable (1.82e-4)" "unprognostic (1.41e-1)" "unprognostic (1.45e-1)" "unprognostic (2.91e-1)" "unprognostic (2.30e-2)" "unprognostic (1.53e-1)" "unprognostic (1.86e-1)" "unprognostic (3.23e-1)" "unprognostic (2.35e-1)" "potential prognostic unfavorable (4.22e-5)" "unprognostic (1.82e-1)" "unprognostic (2.83e-2)" "unprognostic (5.59e-2)" "unprognostic (2.26e-1)" "unprognostic (2.50e-2)" "unprognostic (1.42e-2)" "unprognostic (1.29e-1)" "unprognostic (1.25e-1)" "unprognostic (1.38e-1)" MYO5C MGC74969 ENSG00000128833 "Myosin VC" Q9NQX4 15 52192322-52295804 "Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 288.6;Foveolar cells: 223.9;Respiratory deuterosomal cells: 262.3" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 178.9;endothelial cell: 161.0;ependymal cell: 193.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Lung - Alveolar cells type 2, Skeletal muscle - Endothelial cells, Spleen - Endothelial cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB020790, HPA032115, HPA032116" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 60: Stomach - Digestion" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 12 Cytosol Nucleoplasm "CAB020790: , HPA032115: , HPA032116: " "unprognostic (3.19e-1)" "unprognostic (2.00e-2)" "unprognostic (5.46e-2)" "unprognostic (2.01e-1)" "unprognostic (1.46e-1)" "unprognostic (5.01e-2)" "unprognostic (3.85e-1)" "unprognostic (1.29e-2)" "unprognostic (3.91e-2)" "unprognostic (2.05e-2)" "validated prognostic favorable (2.54e-5)" "validated prognostic favorable (6.28e-4)" "unprognostic (2.78e-1)" "unprognostic (1.22e-1)" "unprognostic (6.10e-2)" "unprognostic (5.09e-2)" "unprognostic (1.97e-1)" "unprognostic (2.71e-1)" "unprognostic (2.80e-1)" "unprognostic (5.94e-2)" "unprognostic (1.20e-1)" "potential prognostic unfavorable (7.53e-4)" "unprognostic (7.10e-2)" "unprognostic (2.41e-1)" "unprognostic (6.05e-2)" "unprognostic (3.89e-1)" "unprognostic (1.89e-3)" "unprognostic (1.56e-1)" "unprognostic (1.78e-1)" "unprognostic (2.14e-2)" MYO6 "DFNA22, DFNB37, KIAA0389" ENSG00000196586 "Myosin VI" Q9UM54 6 75749201-75919537 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Endocytosis, Hearing, Protein transport, Transport" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Cardiomyopathy, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 1170.1;Esophageal apical cells: 1109.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 5.4;MAIT T-cell: 3.0;memory CD4 T-cell: 1.7;memory CD8 T-cell: 3.1;naive CD8 T-cell: 3.0;NK-cell: 2.9" "Group enriched" "Detected in many" 7 "NK-cells: 2.9;T-cells: 5.4" "Cancer enhanced" "Detected in all" "prostate cancer: 146.4" "Adipose visceral - Endothelial cells, Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate basal glandular cells, Skeletal muscle - Endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010762, HPA035482, HPA035483" Enhanced Supported Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 11: Neuronal - Sensory perception" "Cluster 51: Secretory epithelial cells - Mixed function" 90 Nucleoplasm "CAB010762: , HPA035482: , HPA035483: " "unprognostic (2.75e-2)" "unprognostic (6.80e-3)" "unprognostic (1.70e-1)" "potential prognostic unfavorable (4.32e-4)" "unprognostic (9.87e-3)" "unprognostic (5.96e-2)" "unprognostic (3.16e-2)" "unprognostic (1.21e-1)" "unprognostic (4.55e-3)" "unprognostic (4.49e-2)" "validated prognostic favorable (2.23e-12)" "validated prognostic favorable (7.91e-4)" "unprognostic (4.30e-3)" "unprognostic (5.12e-2)" "unprognostic (1.52e-2)" "potential prognostic favorable (5.40e-4)" "unprognostic (3.92e-2)" "unprognostic (9.76e-3)" "unprognostic (4.55e-2)" "unprognostic (2.22e-1)" "unprognostic (2.00e-2)" "unprognostic (1.04e-1)" "unprognostic (1.48e-1)" "unprognostic (5.60e-2)" "unprognostic (5.16e-3)" "unprognostic (2.52e-1)" "unprognostic (9.10e-2)" "unprognostic (1.08e-1)" "unprognostic (1.72e-1)" "unprognostic (1.94e-1)" "unprognostic (8.73e-2)" MYO7A "DFNA11, DFNB2, NSRD2, USH1B" ENSG00000137474 "Myosin VIIA" Q13402 11 77128246-77215241 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hearing "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Deafness, Disease variant, Leber congenital amaurosis, Non-syndromic deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 36.6" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 58.3;Choroid plexus epithelial cells: 69.9;Cone photoreceptor cells: 47.6;Cytotrophoblasts: 57.4;Gonadotrophs: 81.0;Hofbauer cells: 57.8;Migrating cytotrophoblasts: 39.8;Retinal pigment epithelial cells: 81.0;Rod photoreceptor cells: 38.8;Sertoli cells: 131.3" "Group enriched" "Detected in many" 4 "central nervous system macrophage: 20.5;choroid plexus epithelial cell: 59.9;ependymal cell: 20.6;fibroblast: 18.0" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "choroid plexus: 108.5" "Immune cell enhanced" "Detected in some" "classical monocyte: 2.6;intermediate monocyte: 1.7" "Lineage enriched" "Detected in single" 4 "monocytes: 2.6" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Minor Salivary Gland - Macrophages, Pituitary gland - Gonadotropes, Prostate - Fibroblasts, Skeletal muscle - Macrophages, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" CAB034059 Uncertain NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 4 "CAB034059: " "unprognostic (1.24e-1)" "unprognostic (1.61e-3)" "unprognostic (1.37e-1)" "unprognostic (3.29e-1)" "unprognostic (2.82e-2)" "unprognostic (1.69e-1)" "unprognostic (9.00e-2)" "unprognostic (1.89e-2)" "unprognostic (3.86e-2)" "unprognostic (3.31e-2)" "unprognostic (4.17e-3)" "unprognostic (5.52e-2)" "unprognostic (5.38e-2)" "unprognostic (1.63e-1)" "unprognostic (7.11e-2)" "unprognostic (1.86e-1)" "unprognostic (1.57e-2)" "unprognostic (9.85e-2)" "unprognostic (2.66e-1)" "unprognostic (1.39e-1)" "potential prognostic favorable (1.26e-5)" "unprognostic (2.23e-1)" "unprognostic (1.20e-2)" "unprognostic (1.57e-1)" "unprognostic (7.65e-2)" "unprognostic (5.16e-3)" "unprognostic (2.22e-2)" "unprognostic (1.32e-1)" "unprognostic (3.02e-1)" "unprognostic (3.20e-2)" "unprognostic (9.58e-3)" MYO7B ENSG00000169994 "Myosin VIIB" Q6PIF6 2 127535683-127637729 "Predicted intracellular proteins" Differentiation "Actin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "intestine: 73.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 66.6;Colonocytes: 196.1;Enteric stem cells: 68.3;Enteric transient amplifying cells: 77.1;Enterocytes: 304.9;Epididymal principal cells: 84.9;Goblet cells: 139.0;Neuroendocrine cells: 83.3;Neutrophils: 60.4;Proximal tubule cells: 102.7;Tuft cells: 253.6" "Cell type enhanced" "Detected in some" "committed oligodendrocyte precursor: 11.2;oligodendrocyte precursor cell: 8.1" "Group enriched" "Detected in many" 4 "Colon Adenocarcinoma (TCGA): 49.3;Kidney Renal Papillary Cell Carcinoma (TCGA): 15.8;Pancreatic Adenocarcinoma (TCGA): 13.7;Rectum Adenocarcinoma (TCGA): 42.5;Stomach Adenocarcinoma (TCGA): 27.4" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "classical monocyte: 5.7;naive B-cell: 5.9" "Group enriched" "Detected in many" 22 "B-cells: 5.9;dendritic cells: 2.6;monocytes: 5.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 10.1;Leukemia: 24.4" "Kidney - Proximal tubular cells, Liver - Vascular endothelial cells, Prostate - Smooth muscle cells, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Not detected" "Not detected" HPA039131 Enhanced NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 59: Leukemia - T-cell receptor" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 1 "HPA039131: " "unprognostic (7.76e-3)" "unprognostic (5.52e-2)" "unprognostic (1.46e-3)" "unprognostic (4.33e-2)" "unprognostic (8.20e-2)" "unprognostic (1.22e-1)" "unprognostic (2.37e-2)" "unprognostic (5.77e-2)" "validated prognostic favorable (7.99e-6)" "validated prognostic favorable (1.01e-4)" "unprognostic (4.18e-2)" "unprognostic (6.13e-2)" "unprognostic (1.28e-3)" "unprognostic (9.47e-2)" "unprognostic (1.10e-1)" "unprognostic (6.27e-2)" "unprognostic (3.30e-2)" "unprognostic (4.19e-3)" "unprognostic (2.16e-1)" MYO9A "FLJ11061, FLJ13244, MGC71859" ENSG00000066933 "Myosin IXA" B2RTY4 15 71822291-72118577 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, GTPase activation, Motor protein, Myosin" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 57.2" "Cell type enhanced" "Detected in all" "Loop of henle epithelial cells: 761.8;Rod photoreceptor cells: 1298.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039812, HPA040071" Approved Approved "Plasma membrane" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 42: Retina - Visual perception" "Cluster 31: Non-specific - Transcription" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 79: Photoreceptor cells - Phototransduction" 9 "Plasma membrane" "HPA039812: , HPA040071: " "unprognostic (9.32e-2)" "unprognostic (4.53e-2)" "unprognostic (2.57e-1)" "unprognostic (1.01e-1)" "unprognostic (1.48e-1)" "unprognostic (1.36e-1)" "unprognostic (1.37e-1)" "unprognostic (5.04e-3)" "unprognostic (7.69e-2)" "unprognostic (5.56e-3)" "validated prognostic favorable (1.06e-7)" "validated prognostic favorable (3.34e-6)" "unprognostic (3.58e-3)" "unprognostic (3.97e-1)" "unprognostic (3.50e-2)" "unprognostic (1.60e-3)" "unprognostic (1.27e-1)" "unprognostic (1.04e-1)" "unprognostic (1.06e-2)" "unprognostic (3.48e-2)" "unprognostic (8.76e-2)" "unprognostic (1.21e-2)" "unprognostic (4.11e-1)" "unprognostic (5.25e-2)" "unprognostic (3.87e-3)" "unprognostic (5.87e-2)" "unprognostic (2.26e-1)" "unprognostic (4.44e-1)" "unprognostic (1.12e-1)" "unprognostic (5.40e-3)" MYO9B CELIAC4 ENSG00000099331 "Myosin IXB" Q13459 19 17075777-17214537 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, GTPase activation, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 145.0" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 540.3;Macrophages: 431.0;monocytes: 883.5;Neutrophil progenitors: 407.5;Neutrophils: 1066.9;Sertoli cells: 406.2" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 320.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037190, HPA042043" Approved Supported Cytosol NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 5: Spleen - Immune response" "Cluster 11: White matter - Signal transduction" "Cluster 23: Non-specific - Transcription" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 23 Cytosol "CAB037190: , HPA042043: " "unprognostic (1.02e-1)" "unprognostic (1.91e-1)" "unprognostic (2.91e-2)" "unprognostic (5.34e-2)" "unprognostic (2.06e-1)" "unprognostic (2.47e-1)" "unprognostic (2.26e-1)" "unprognostic (1.67e-1)" "unprognostic (3.99e-3)" "unprognostic (2.40e-1)" "potential prognostic unfavorable (7.05e-4)" "unprognostic (1.44e-1)" "unprognostic (2.76e-1)" "unprognostic (1.58e-3)" "unprognostic (1.44e-1)" "unprognostic (1.99e-1)" "unprognostic (9.22e-2)" "unprognostic (2.68e-1)" "unprognostic (1.20e-1)" "unprognostic (5.53e-2)" "unprognostic (1.88e-2)" "unprognostic (1.26e-1)" "unprognostic (6.38e-3)" "unprognostic (1.15e-2)" "unprognostic (2.64e-1)" "potential prognostic favorable (6.07e-4)" "unprognostic (1.55e-1)" "unprognostic (1.19e-1)" "unprognostic (1.70e-1)" "unprognostic (8.96e-2)" "unprognostic (1.04e-1)" MYOC "GLC1A, JOAG1, TIGR" ENSG00000034971 Myocilin Q99972 1 171635417-171652688 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Disease variant, Glaucoma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 95.1;tongue: 103.4" "Group enriched" "Detected in some" 6 "Fibro-adipogenic progenitors: 89.0;Fibroblasts: 115.0;Melanocytes: 64.4;Peritubular myoid cells: 33.2" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 9 "Skin Cutaneous Melanoma (TCGA): 21.4" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 45 "Rhabdoid: 209.3" "Colon - Fibroblasts, Minor Salivary Gland - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA027364 Uncertain "Secreted to extracellular matrix" "No annotated function" NA NA 15000000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 30: White matter - Myelination" "Cluster 5: Rhabdoid - Unknown function" "Cluster 108: Fibroblasts - ECM organization" 6 "HPA027364: " "unprognostic (1.46e-1)" "unprognostic (1.56e-2)" "unprognostic (2.10e-1)" "unprognostic (5.63e-1)" "unprognostic (2.68e-1)" "unprognostic (1.54e-2)" "unprognostic (1.57e-1)" "unprognostic (9.00e-2)" MYOCD MYCD ENSG00000141052 Myocardin Q8IZQ8 17 12665890-12768949 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 25.4" "Group enriched" "Detected in many" 5 "Cardiomyocytes: 489.8;Endometrial stromal cells: 138.6;Peritubular myoid cells: 245.3;Smooth muscle cells: 311.9;Vascular smooth muscle cells: 325.5" "Cell type enriched" "Detected in many" 9 "vascular associated smooth muscle cell: 547.0" "Cancer enhanced" "Detected in some" "Stomach Adenocarcinoma (TCGA): 4.2" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "testis cancer: 11.8" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Adrenal gland - Smooth muscle cells, Breast - Endothelial cells, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Skin - Smooth muscle cells, Spleen - Smooth muscle cells, Thyroid gland - Smooth muscle cells" "Not detected" "Not detected" "Region enriched" "Detected in some" 4 "cerebellum: 5.4" "CAB046485, HPA071528, HPA072582" Approved Approved Nucleoplasm NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 55: Lymphoma - Immune response" "Cluster 62: Smooth muscle cells - Muscle contraction" 8 Nucleoplasm "CAB046485: , HPA071528: , HPA072582: " "unprognostic (2.47e-3)" "unprognostic (2.06e-2)" "unprognostic (1.25e-1)" "unprognostic (2.51e-2)" "unprognostic (3.44e-2)" "unprognostic (4.36e-2)" "unprognostic (2.14e-2)" "unprognostic (6.51e-2)" "unprognostic (6.02e-2)" MYOCOS ENSG00000283683 "Myocilin opposite strand" A0A1B0GUC4 1 171600621-171638799 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "cervix: 5.0;epididymis: 3.5" "Cell type enhanced" "Detected in many" "Early spermatids: 26.5;Endometrial ciliated cells: 29.0;Endometrial glandular cells: 14.6;Oocytes: 96.7;Proximal tubule cells: 39.8" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Kidney Renal Clear Cell Carcinoma (TCGA): 26.5;Uterine Corpus Endometrial Carcinoma (TCGA): 17.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 4.1" "Testis - Early spermatids, Testis - Late spermatids" NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 51: Secretory epithelial cells - Mixed function" "unprognostic (1.32e-1)" "unprognostic (6.96e-2)" "unprognostic (3.21e-2)" "unprognostic (2.40e-1)" "unprognostic (3.20e-1)" "unprognostic (1.63e-2)" "unprognostic (7.55e-3)" "unprognostic (5.90e-2)" MYOD1 "bHLHc1, MYF3, MYOD, PUM" ENSG00000129152 "Myogenic differentiation 1" P15172 11 17719571-17722136 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Myogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "skeletal muscle: 34.4" "Group enriched" "Detected in some" 8 "Myonuclei: 16.9;Myosatellite cells: 40.3;Thymic myoid cells: 10.9" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Ovary Serous Cystadenocarcinoma (TCGA): 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 65 "Sarcoma: 76.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA055436, HPA078647" Enhanced Nucleoplasm NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 39 Nucleoplasm "HPA055436: , HPA078647: " "unprognostic (3.82e-1)" "unprognostic (1.23e-1)" MYOF "FER1L3, KIAA1207" ENSG00000138119 Myoferlin Q9NZM1 10 93306429-93482334 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 1114.0;Endometrial secretory cells: 712.1;Prostatic hillock cells: 676.7;Urothelial cells: 1157.3" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 264.4;choroid plexus epithelial cell: 346.6;endothelial cell: 251.4;pericyte: 248.4;vascular associated smooth muscle cell: 224.5" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "choroid plexus: 78.3" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 20.4;non-classical monocyte: 26.7" "Group enriched" "Detected in many" 57 "dendritic cells: 8.1;monocytes: 26.7" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014245 Enhanced Supported "Vesicles,Plasma membrane,Primary cilium,Primary cilium tip,Centriolar satellite,Basal body" NA NA 62000 "Cluster 40: Monocytes - Innate immune response" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 8: Immune cells - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 51: Secretory epithelial cells - Mixed function" 5 "Vesicles, Plasma membrane, Centriolar satellite" "Primary cilium, Primary cilium tip, Basal body" "HPA014245: " "unprognostic (1.13e-1)" "unprognostic (2.50e-1)" "unprognostic (1.25e-1)" "unprognostic (1.34e-1)" "unprognostic (3.56e-1)" "unprognostic (3.64e-2)" "unprognostic (1.12e-1)" "unprognostic (6.23e-3)" "unprognostic (9.08e-2)" "unprognostic (4.73e-1)" "potential prognostic favorable (4.25e-5)" "unprognostic (1.51e-1)" "unprognostic (1.38e-1)" "unprognostic (2.67e-2)" "unprognostic (1.89e-1)" "unprognostic (5.30e-3)" "unprognostic (4.18e-2)" "unprognostic (2.64e-2)" "unprognostic (2.76e-3)" "unprognostic (6.93e-3)" "unprognostic (4.41e-3)" "potential prognostic unfavorable (4.95e-4)" "unprognostic (2.69e-2)" "unprognostic (1.37e-1)" "unprognostic (6.53e-2)" "unprognostic (7.82e-2)" "unprognostic (3.01e-2)" "unprognostic (3.40e-1)" "unprognostic (4.88e-3)" "unprognostic (5.23e-2)" "unprognostic (4.34e-3)" MYOG "bHLHc3, MYF4" ENSG00000122180 Myogenin P15173 1 203083129-203086012 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Cell cycle, Differentiation, Myogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "skeletal muscle: 98.4;tongue: 43.5" "Group enriched" "Detected in some" 53 "Myonuclei: 31.8;Thymic myoid cells: 53.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Head and Neck Squamous Cell Carcinoma (TCGA): 6.2;Testicular Germ Cell Tumor (TCGA): 3.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 61 "Sarcoma: 51.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA028336 Supported Nucleoplasm NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 35: Non-specific - DNA binding" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 36 Nucleoplasm "HPA028336: " "unprognostic (3.06e-3)" "unprognostic (7.33e-1)" MYOM1 ENSG00000101605 "Myomesin 1" P52179 18 3066807-3219968 "Predicted intracellular proteins" "Muscle protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 18 "heart muscle: 375.8;skeletal muscle: 762.9;tongue: 399.9" "Group enriched" "Detected in many" 9 "Cardiomyocytes: 1522.1;Myonuclei: 3793.5" "Cell type enhanced" "Detected in all" "pericyte: 169.9;vascular associated smooth muscle cell: 410.1" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 8.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 3.2" "Adipose subcutaneous - Smooth muscle cells, Colon - Smooth muscle cells, Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA014305, HPA049193" Enhanced NA NA 13000 "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 19: Astrocytes - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 55: Myocytes - Oxidative muscle function" 3 "HPA014305: , HPA049193: " "unprognostic (1.89e-1)" "unprognostic (1.46e-1)" "unprognostic (1.51e-1)" "unprognostic (2.80e-1)" "unprognostic (6.51e-2)" "validated prognostic favorable (1.07e-5)" "validated prognostic favorable (2.25e-5)" "unprognostic (7.12e-2)" "unprognostic (2.30e-1)" "unprognostic (2.72e-2)" "unprognostic (1.24e-1)" "unprognostic (2.63e-1)" "unprognostic (6.45e-2)" "unprognostic (7.03e-2)" "unprognostic (5.86e-2)" "unprognostic (1.89e-1)" "unprognostic (2.20e-2)" MYOM2 ENSG00000036448 "Myomesin 2" P54296 8 2045046-2165552 "Predicted intracellular proteins" "Muscle protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "heart muscle: 324.6;skeletal muscle: 372.0" "Group enriched" "Detected in many" 5 "Cardiomyocytes: 417.0;Myonuclei: 115.0" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "Bone cancer: 8.7;Myeloma: 7.3" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA001765, HPA005953" Enhanced Approved Mitochondria NA NA 280000 "Cluster 41: Striated muscle - Muscle contraction" "Cluster 53: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 55: Myocytes - Oxidative muscle function" 12 Mitochondria "HPA001765: , HPA005953: " "unprognostic (1.44e-2)" "unprognostic (8.44e-2)" "unprognostic (1.82e-3)" "unprognostic (9.21e-2)" "unprognostic (2.21e-1)" MYOM3 FLJ35961 ENSG00000142661 "Myomesin 3" Q5VTT5 1 24056035-24112135 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "heart muscle: 209.7;skeletal muscle: 308.7;tongue: 238.9" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 227.0;Myonuclei: 685.8;Thymic myoid cells: 172.7" "Cell type enhanced" "Detected in single" "ependymal cell: 1.2" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 34.2" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "colorectal cancer: 3.9;Kidney cancer: 8.9;Rhabdoid: 9.5" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Skeletal muscle - Skeletal myocytes, Testis - Sertoli cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA028132, HPA028340" Approved "Golgi apparatus,Vesicles,Cytokinetic bridge" Yes No 750000 "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 25: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 46: Skeletal myocytes - Muscle structure & formation" Vesicles "Golgi apparatus, Cytokinetic bridge" "HPA028132: , HPA028340: " "unprognostic (1.12e-1)" "unprognostic (1.08e-1)" "unprognostic (1.11e-1)" "unprognostic (5.07e-2)" "unprognostic (8.46e-2)" "validated prognostic favorable (1.01e-4)" "validated prognostic favorable (2.34e-5)" "potential prognostic favorable (2.20e-4)" "unprognostic (1.05e-3)" "unprognostic (1.01e-2)" "unprognostic (3.19e-2)" "unprognostic (1.37e-1)" "unprognostic (1.15e-2)" "unprognostic (2.68e-2)" "unprognostic (2.42e-2)" MYORG "KIAA1161, NET37" ENSG00000164976 "Myogenesis regulating glycosidase (putative)" Q6NSJ0 9 34366666-34376898 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 78.8" "Cell type enhanced" "Detected in many" "Astrocytes: 35.7;Bergmann glia: 25.8;Colonocytes: 48.6;Cytotrophoblasts: 72.6;Enterocytes: 69.7;Hepatocytes: 59.2;Migrating cytotrophoblasts: 31.9;Parietal cells: 35.4" "Cell type enhanced" "Detected in many" "astrocyte: 32.1;Bergmann glia: 29.7;endothelial cell: 27.8;ependymal cell: 23.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060533, HPA067487" Enhanced Approved Mitochondria NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 6 Mitochondria "HPA060533: , HPA067487: " "unprognostic (1.02e-2)" "unprognostic (3.70e-2)" "unprognostic (1.83e-2)" "unprognostic (1.78e-2)" "unprognostic (2.35e-1)" "unprognostic (1.69e-1)" "unprognostic (2.03e-3)" "unprognostic (1.03e-1)" "unprognostic (4.86e-1)" "potential prognostic favorable (9.31e-9)" "unprognostic (1.18e-2)" "unprognostic (1.24e-2)" "unprognostic (2.21e-1)" "unprognostic (9.48e-3)" "unprognostic (7.02e-2)" "unprognostic (1.72e-1)" "unprognostic (1.14e-1)" "unprognostic (5.14e-2)" "unprognostic (2.45e-1)" "unprognostic (2.07e-3)" "unprognostic (8.76e-2)" "unprognostic (1.06e-1)" "unprognostic (2.96e-3)" "unprognostic (6.84e-2)" "unprognostic (2.69e-1)" "unprognostic (1.62e-2)" "unprognostic (2.19e-1)" "unprognostic (1.56e-1)" "unprognostic (1.23e-1)" MYOT "LGMD1, LGMD1A, TTID" ENSG00000120729 Myotilin Q9UBF9 5 137867858-137887851 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin-binding, Muscle protein" "Disease variant, Limb-girdle muscular dystrophy, Myofibrillar myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 60 "skeletal muscle: 2045.0;tongue: 1904.0" "Cell type enriched" "Detected in many" 5 "Myonuclei: 3614.6" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Head and Neck Squamous Cell Carcinoma (TCGA): 7.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Sarcoma: 13.3" "Colon - Enteric glia cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA037733, HPA037734" Enhanced NA NA 3500 "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 7 "HPA037733: , HPA037734: " "unprognostic (8.43e-2)" "unprognostic (1.86e-2)" "potential prognostic unfavorable (1.13e-4)" "unprognostic (1.90e-1)" "unprognostic (1.87e-3)" "unprognostic (1.08e-3)" "unprognostic (7.76e-2)" MYOZ1 "CS-2, FATZ, MYOZ" ENSG00000177791 "Myozenin 1" Q9NP98 10 73631612-73641474 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 81 "skeletal muscle: 6684.6;tongue: 3089.0" "Group enriched" "Detected in some" 9 "Myonuclei: 381.0;Thymic myoid cells: 690.7" "Cell type enhanced" "Detected in some" "vascular associated smooth muscle cell: 5.4" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 13.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "testis cancer: 6.7" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Heart muscle - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes" "Region enriched" "Detected in single" 17 "olfactory bulb: 3.9" "Low region specificity" "Detected in all" "HPA037848, HPA038437" Enhanced NA NA 53000 "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 39: Astrocytes - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 36 "HPA037848: , HPA038437: " "unprognostic (6.17e-2)" "unprognostic (3.75e-2)" "unprognostic (6.77e-2)" "unprognostic (5.50e-2)" "unprognostic (2.89e-2)" "unprognostic (2.35e-2)" "potential prognostic favorable (2.10e-5)" "potential prognostic favorable (8.57e-5)" "unprognostic (1.35e-1)" "unprognostic (2.21e-1)" "unprognostic (7.31e-2)" "unprognostic (4.17e-1)" "unprognostic (5.22e-3)" "unprognostic (3.71e-2)" "unprognostic (2.12e-1)" "unprognostic (1.33e-1)" "unprognostic (2.61e-1)" MYOZ2 "C4orf5, CS-1, FATZ-2" ENSG00000172399 "Myozenin 2" Q9NPC6 4 119135832-119187789 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 722.0;skeletal muscle: 222.0;tongue: 162.0" "Group enriched" "Detected in some" 6 "Cardiomyocytes: 1090.3;Myonuclei: 351.6" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Head and Neck Squamous Cell Carcinoma (TCGA): 2.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Sarcoma: 3.3;skin cancer: 2.7" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Cardiomyocytes, Lung - Smooth muscle cells, Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA035763, HPA035764" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 41: Striated muscle - Muscle contraction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 12 "Nucleoplasm, Cytosol" "HPA035763: , HPA035764: " "unprognostic (3.64e-2)" "unprognostic (1.79e-1)" "unprognostic (1.53e-2)" "unprognostic (4.13e-3)" MYOZ3 "CS-3, CS3, FATZ-3, FRP3" ENSG00000164591 "Myozenin 3" Q8TDC0 5 150660882-150679368 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 40 "skeletal muscle: 219.3;tongue: 185.2" "Group enriched" "Detected in many" 8 "Myonuclei: 165.4;Peritubular myoid cells: 63.1" "Cell type enhanced" "Detected in many" "Bergmann glia: 11.0" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 3.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 2.9;Neuroblastoma: 3.6" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Testis - Peritubular cells, Thyroid gland - Fibroblasts" "Not detected" "Not detected" "Not detected" "Not detected" HPA039166 Enhanced NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 43: Hindbrain - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 44 "HPA039166: " "unprognostic (1.19e-1)" "unprognostic (1.65e-1)" "unprognostic (2.39e-1)" "unprognostic (3.58e-2)" "unprognostic (4.99e-2)" "unprognostic (5.09e-2)" "unprognostic (1.93e-1)" "unprognostic (1.69e-3)" "unprognostic (2.25e-1)" MYPN MYOP ENSG00000138347 Myopalladin Q86TC9 10 68087897-68212017 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Cardiomyopathy, Disease variant, Nemaline myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 64.0;skeletal muscle: 269.9;tongue: 171.2" "Cell type enriched" "Detected in many" 4 "Myonuclei: 2111.1" "Cell type enriched" "Detected in some" 7 "hippocampal CA4: 25.8" "Cancer enhanced" "Detected in single" "Head and Neck Squamous Cell Carcinoma (TCGA): 1.9" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 27 "NK-cell: 1.4;plasmacytoid DC: 4.4" "Group enriched" "Detected in many" 27 "dendritic cells: 4.4;NK-cells: 1.4" "Cancer enriched" "Detected in many" 5 "Adrenocortical cancer: 85.1" "Skeletal muscle - Skeletal myocytes, Skin - Hair cortex cells, Skin - Inner root sheath cells" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA036299, HPA061494" Enhanced Supported Nucleoplasm,Vesicles,Cytosol No No "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 29: Forebrain - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 2 Nucleoplasm "Vesicles, Cytosol" "HPA036299: , HPA061494: " "unprognostic (1.19e-2)" "unprognostic (2.20e-1)" MYPOP P42pop ENSG00000176182 "Myb related transcription factor, partner of profilin" Q86VE0 19 45890023-45902613 "Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065307 Approved Nucleoplasm NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 24: Non-specific - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 4: Non-specific - Transcription" "Cluster 79: Photoreceptor cells - Phototransduction" 34 Nucleoplasm "HPA065307: " "unprognostic (4.48e-3)" "unprognostic (1.05e-1)" "unprognostic (2.87e-2)" "unprognostic (1.58e-1)" "unprognostic (1.05e-1)" "unprognostic (1.99e-1)" "unprognostic (3.63e-2)" "unprognostic (1.09e-1)" "unprognostic (8.98e-3)" "unprognostic (5.13e-2)" "unprognostic (1.18e-3)" "unprognostic (1.14e-1)" "unprognostic (2.30e-1)" "potential prognostic unfavorable (8.54e-5)" "unprognostic (2.33e-3)" "unprognostic (1.39e-2)" "unprognostic (3.57e-1)" "unprognostic (3.24e-3)" "unprognostic (3.23e-3)" "unprognostic (1.29e-2)" "unprognostic (1.94e-1)" "unprognostic (3.69e-3)" "unprognostic (7.92e-2)" "unprognostic (2.50e-2)" "unprognostic (4.44e-1)" "unprognostic (2.59e-1)" "unprognostic (9.45e-2)" "unprognostic (2.05e-2)" "unprognostic (3.10e-1)" "unprognostic (7.15e-3)" "unprognostic (1.53e-2)" MYRF "C11orf9, MRF, Ndt80, pqn-47" ENSG00000124920 "Myelin regulatory factor" Q9Y2G1 11 61752636-61788518 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding, Hydrolase, Protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 69.1;stomach 1: 47.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 141.5;Cholangiocytes: 63.2;Epicardial cells: 111.4;Foveolar cells: 150.5;Gastric chief cells: 76.4;Mesothelial cells: 101.6;Mucous neck cells: 72.6;Oligodendrocytes: 387.4;Pancreatic duct cells: 55.4;Parietal cells: 77.8;Retinal pigment epithelial cells: 349.6" "Group enriched" "Detected in many" 17 "committed oligodendrocyte precursor: 291.3;oligodendrocyte: 415.4" "Cancer enhanced" "Detected in many" "Stomach Adenocarcinoma (TCGA): 35.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 52.9" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 1, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018310 Approved Nucleoplasm,Cytosol NA NA 210000 "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 72: Neuronal - Signal transduction" "Cluster 80: Oligodendrocytes - Myelination" Nucleoplasm Cytosol "HPA018310: " "unprognostic (1.28e-1)" "unprognostic (7.64e-2)" "unprognostic (1.66e-1)" "unprognostic (5.62e-2)" "unprognostic (3.36e-1)" "potential prognostic favorable (1.48e-4)" "unprognostic (4.15e-2)" "potential prognostic unfavorable (2.86e-4)" "unprognostic (7.86e-2)" "unprognostic (1.09e-3)" "unprognostic (1.33e-1)" "unprognostic (2.72e-3)" "unprognostic (1.80e-2)" "unprognostic (3.93e-1)" "unprognostic (1.47e-2)" "unprognostic (9.16e-3)" "unprognostic (3.18e-1)" "potential prognostic unfavorable (5.43e-5)" "unprognostic (2.51e-1)" "unprognostic (1.03e-1)" "unprognostic (1.80e-1)" "unprognostic (7.03e-2)" "unprognostic (1.56e-2)" MYRFL "bcm1377, C12orf15, C12orf28, FLJ25056" ENSG00000166268 "Myelin regulatory factor like" Q96LU7 12 69825227-69959097 "Predicted intracellular proteins, Predicted membrane proteins" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "intestine: 21.6" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 81.0;Early spermatids: 57.4;Endometrial secretory cells: 83.9;Enterocytes: 179.8;Epididymal clear cells: 112.3;Late spermatids: 57.2;Loop of henle epithelial cells: 69.6;Renal connecting tubule cells: 94.5;Retinal pigment epithelial cells: 187.6" "Cell type enhanced" "Detected in many" "LAMP5-LHX6 and Chandelier: 59.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 3.6" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA049340 Approved Approved Nucleoli "Intracellular and membrane" Other NA NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 27: Breast cancer - Unknown function" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" Nucleoli "HPA049340: " "unprognostic (8.01e-3)" "unprognostic (4.41e-2)" "unprognostic (1.98e-1)" "unprognostic (6.55e-3)" "unprognostic (1.29e-3)" "unprognostic (2.05e-3)" "unprognostic (2.98e-2)" "unprognostic (3.08e-1)" "unprognostic (1.83e-2)" MYRIP "DKFZp586F1018, exophilin-8, SLAC2-C, SLAC2C" ENSG00000170011 "Myosin VIIA and Rab interacting protein" Q8NFW9 3 39808914-40260321 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 34.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 478.0;Choroid plexus epithelial cells: 1276.4;Pituicytes/FSCs: 1570.3;Retinal pigment epithelial cells: 5171.0;Salivary acinar cells: 478.8;Vascular endothelial cells: 563.6" "Cell type enhanced" "Detected in all" "endothelial cell: 1903.7" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 23.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "colorectal cancer: 2.0;Neuroblastoma: 5.4;prostate cancer: 6.3" "Minor Salivary Gland - Minor salivary glandular cells, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006433 Approved "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus" NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 24: Neurons - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" 6 "Nucleoplasm, Nucleoli fibrillar center, Golgi apparatus" "HPA006433: " "unprognostic (2.14e-2)" "unprognostic (8.92e-2)" "unprognostic (2.86e-1)" "unprognostic (2.00e-1)" "unprognostic (6.36e-2)" "unprognostic (1.61e-1)" "unprognostic (2.82e-1)" "potential prognostic favorable (2.59e-9)" "unprognostic (1.19e-3)" "unprognostic (2.14e-2)" "unprognostic (1.32e-3)" "unprognostic (3.38e-3)" "unprognostic (2.25e-1)" "potential prognostic unfavorable (9.84e-4)" "unprognostic (1.05e-1)" "unprognostic (1.42e-1)" "unprognostic (2.34e-2)" "unprognostic (1.25e-1)" "unprognostic (5.52e-2)" "unprognostic (2.26e-1)" MYSM1 KIAA1915 ENSG00000162601 "Myb like, SWIRM and MPN domains 1" Q5VVJ2 1 58643440-58700090 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Immunity, Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, Chromatin regulator, DNA-binding, Hydrolase, Metalloprotease, Protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054291, HPA057306" Approved Supported Nucleoplasm,Nucleoli NA NA "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 53: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 7: Non-specific - Transcription" 7 Nucleoplasm Nucleoli "HPA054291: , HPA057306: " "unprognostic (8.15e-3)" "unprognostic (1.31e-1)" "unprognostic (2.79e-2)" "unprognostic (8.79e-3)" "unprognostic (2.42e-1)" "unprognostic (1.47e-2)" "unprognostic (3.98e-2)" "unprognostic (2.68e-1)" "potential prognostic favorable (7.82e-4)" "unprognostic (3.63e-1)" "unprognostic (1.97e-1)" "unprognostic (4.67e-2)" "potential prognostic favorable (5.74e-4)" "potential prognostic unfavorable (5.44e-4)" "unprognostic (2.23e-2)" "unprognostic (2.29e-3)" "unprognostic (3.52e-2)" "unprognostic (1.87e-3)" "unprognostic (3.42e-2)" "unprognostic (5.66e-2)" "unprognostic (3.31e-1)" "unprognostic (2.62e-1)" "unprognostic (2.31e-2)" "unprognostic (2.89e-2)" "unprognostic (8.11e-2)" "unprognostic (2.03e-1)" "unprognostic (8.76e-3)" "unprognostic (1.15e-1)" "unprognostic (2.95e-1)" "unprognostic (2.23e-2)" "unprognostic (1.53e-1)" MYT1 "MTF1, MYTI, NZF2, PLPB1, ZC2H2C1, ZC2HC4A" ENSG00000196132 "Myelin transcription factor 1" Q01538 20 64102394-64242253 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 32.9" "Cell type enriched" "Detected in some" 9 "Oligodendrocyte progenitor cells: 238.7" "Cell type enriched" "Detected in many" 4 "oligodendrocyte precursor cell: 284.5" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 4.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 14.2" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Pituitary gland - Lactotropes, Spleen - B-cells (Spleen), Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 30.2" "HPA006303, HPA067092" Uncertain Enhanced Nucleoplasm,Cytosol NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 35: Non-specific - DNA binding" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 1 Nucleoplasm Cytosol "HPA006303: , HPA067092: " "unprognostic (1.15e-2)" "unprognostic (1.49e-1)" "unprognostic (9.85e-2)" "potential prognostic favorable (4.11e-4)" "unprognostic (4.06e-2)" MYT1L "KIAA1106, NZF1, ZC2H2C2, ZC2HC4B" ENSG00000186487 "Myelin transcription factor 1 like" Q9UL68 2 1789113-2331664 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Autism spectrum disorder, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 28.6;pituitary gland: 10.5" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 329.7;Brain excitatory neurons: 721.1;Brain inhibitory neurons: 855.3;Early primary spermatocytes: 259.2;Lactotrophs: 1427.3;Oligodendrocyte progenitor cells: 310.0;Other brain neurons: 538.8;Retinal amacrine cells: 592.1;Retinal ganglion cells: 679.8;Retinal horizontal cells: 769.3;Somatotrophs: 979.4;Thyrotrophs: 1011.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Neuroblastoma: 10.2" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Beta cells, Pituitary gland - Lactotropes, Prostate - Smooth muscle cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060245 Approved Vesicles NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 2 Vesicles "HPA060245: " "unprognostic (7.32e-2)" "unprognostic (5.94e-2)" "unprognostic (2.81e-3)" "unprognostic (1.07e-2)" "unprognostic (1.50e-1)" "unprognostic (1.09e-2)" MYZAP "GCOM1, Gup, Gup1, MYOZAP" ENSG00000263155 "Myocardial zonula adherens protein" P0CAP1 15 57591904-57685364 "Predicted intracellular proteins" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "heart muscle: 551.2" "Cell type enhanced" "Detected in single" "Kupffer cells: 1.0" "Group enriched" "Detected in some" 4 "lower rhombic lip: 1.3;upper rhombic lip: 1.3" "Cancer enriched" "Detected in many" 6 "Kidney Chromophobe (TCGA): 84.4" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "naive B-cell: 3.4;naive CD4 T-cell: 2.0" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Bile duct cancer: 15.3" "Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Pituitary gland - Gonadotropes, Prostate - Smooth muscle cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA039827 Approved NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 35: Non-specific - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 1 "HPA039827: " "potential prognostic favorable (2.06e-5)" "unprognostic (6.74e-3)" "unprognostic (4.38e-2)" "unprognostic (1.80e-1)" "unprognostic (1.03e-1)" "unprognostic (1.35e-1)" "unprognostic (2.40e-1)" "unprognostic (1.79e-1)" "unprognostic (5.50e-2)" "unprognostic (1.41e-2)" "unprognostic (1.13e-1)" "unprognostic (2.83e-1)" "unprognostic (7.19e-3)" "unprognostic (3.13e-1)" "unprognostic (2.84e-2)" "unprognostic (9.20e-2)" "unprognostic (9.07e-2)" "unprognostic (9.75e-2)" "unprognostic (1.94e-1)" "unprognostic (1.84e-1)" "unprognostic (2.37e-2)" "unprognostic (9.97e-2)" "unprognostic (1.57e-1)" "unprognostic (6.63e-3)" MZB1 "HSPC190, MEDA-7, MGC29506, PACAP, pERp1" ENSG00000170476 "Marginal zone B and B1 cell specific protein" Q8WU39 5 139387467-139390081 "Predicted secreted proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 84.5;lymphoid tissue: 214.9" "Cell type enriched" "Detected in many" 8 "Plasma cells: 4016.9" "Group enriched" "Detected in some" 10 "ependymal cell: 2.5;leukocyte: 7.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 5 "memory B-cell: 160.8;plasmacytoid DC: 570.5" "Group enriched" "Detected in many" 115 "B-cells: 160.8;dendritic cells: 570.5" "Cancer enriched" "Detected in some" 5 "Myeloma: 759.0" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA043745, HPA052694" Enhanced Approved "Golgi apparatus" "Secreted to blood" Other NA NA 260000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 44: Plasma cells - Antibody production & secretion" 6 "Golgi apparatus" "HPA043745: , HPA052694: " "unprognostic (1.08e-1)" "potential prognostic favorable (5.58e-4)" "unprognostic (1.29e-3)" "unprognostic (1.24e-1)" "unprognostic (3.48e-1)" "potential prognostic favorable (1.29e-4)" "unprognostic (2.68e-3)" "unprognostic (4.10e-2)" "potential prognostic unfavorable (2.83e-4)" "unprognostic (7.43e-2)" "unprognostic (1.77e-2)" "unprognostic (2.53e-2)" "unprognostic (4.01e-3)" "unprognostic (2.00e-1)" "unprognostic (6.01e-2)" "unprognostic (5.00e-3)" "unprognostic (4.17e-2)" "unprognostic (3.36e-1)" "unprognostic (2.23e-2)" "unprognostic (1.20e-1)" "unprognostic (1.98e-2)" "unprognostic (7.35e-2)" "unprognostic (8.93e-2)" "unprognostic (6.28e-2)" "unprognostic (5.11e-1)" "unprognostic (6.90e-2)" "unprognostic (2.54e-1)" MZF1 "MZF-1, MZF1B, Zfp98, ZNF42, ZSCAN6" ENSG00000099326 "Myeloid zinc finger 1" P28698 19 58561931-58573575 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA001757 Approved Supported Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 107: Ciliated cells - Cilia assembly & function" 14 Nucleoplasm "HPA001757: " "unprognostic (3.47e-2)" "unprognostic (1.33e-1)" "unprognostic (3.31e-1)" "unprognostic (1.67e-1)" "unprognostic (4.17e-3)" "unprognostic (1.56e-1)" "unprognostic (2.06e-1)" "unprognostic (1.56e-1)" "unprognostic (1.26e-2)" "unprognostic (8.92e-2)" "unprognostic (2.43e-2)" "unprognostic (1.83e-1)" "unprognostic (3.28e-2)" "unprognostic (1.22e-2)" "unprognostic (2.27e-2)" "unprognostic (2.82e-1)" "unprognostic (2.33e-1)" "unprognostic (2.39e-1)" "unprognostic (5.94e-2)" "unprognostic (3.17e-1)" "unprognostic (2.89e-2)" "unprognostic (9.96e-3)" "unprognostic (3.87e-2)" "unprognostic (8.29e-3)" "unprognostic (3.31e-2)" "unprognostic (4.25e-2)" "unprognostic (6.99e-2)" "unprognostic (2.13e-1)" "unprognostic (1.02e-1)" "unprognostic (2.38e-2)" "unprognostic (4.40e-2)" MZT1 "C13orf37, FLJ21869, LOC440145, MGC150539, MOZART1, RP11-11C5.2" ENSG00000204899 "Mitotic spindle organizing protein 1" Q08AG7 13 72708367-72727629 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 121.4;Gastric progenitor cells: 102.5;Megakaryocytes: 98.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063299, HPA066715" Approved NA Yes "Cluster 5: Non-specific - Cell proliferation" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 33: Neurons - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 14 "HPA063299: , HPA066715: " "unprognostic (3.99e-2)" "unprognostic (1.99e-1)" "unprognostic (3.62e-3)" "unprognostic (4.90e-1)" "unprognostic (1.13e-1)" "unprognostic (4.22e-1)" "unprognostic (1.97e-1)" "unprognostic (1.87e-3)" "unprognostic (2.70e-3)" "unprognostic (4.78e-3)" "unprognostic (4.17e-1)" "unprognostic (8.14e-2)" "validated prognostic unfavorable (1.76e-5)" "validated prognostic unfavorable (1.14e-6)" "potential prognostic unfavorable (1.66e-5)" "unprognostic (1.60e-3)" "unprognostic (1.06e-1)" "unprognostic (9.14e-2)" "unprognostic (7.80e-2)" "unprognostic (1.88e-2)" "unprognostic (1.13e-2)" "unprognostic (4.99e-3)" "unprognostic (2.54e-2)" "unprognostic (1.48e-1)" "unprognostic (1.15e-1)" "unprognostic (6.39e-2)" "unprognostic (8.08e-2)" "unprognostic (2.33e-1)" "unprognostic (1.34e-1)" "unprognostic (3.00e-1)" MZT2A "FAM128A, MOZART2A" ENSG00000173272 "Mitotic spindle organizing protein 2A" Q6P582 2 131464900-131492743 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 244.0" "Cell type enhanced" "Detected in all" "Epididymal efferent duct absorptive cells: 596.6;Epididymal principal cells: 507.2;Esophageal apical cells: 549.0;Esophageal basal cells: 421.6;Esophageal suprabasal cells: 461.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 79.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "HPA051758, HPA052623" Approved Approved Centrosome,Cytosol NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 35: RS4;11 - Unknown function" "Cluster 15: Non-specific - Protein processing" 8 Centrosome Cytosol "HPA051758: , HPA052623: " "unprognostic (6.04e-2)" "unprognostic (1.92e-2)" "unprognostic (4.31e-2)" "unprognostic (4.83e-2)" "unprognostic (3.57e-2)" "unprognostic (1.28e-2)" "unprognostic (3.33e-1)" "unprognostic (7.76e-2)" "unprognostic (1.92e-2)" "unprognostic (1.97e-3)" "potential prognostic unfavorable (3.82e-5)" "unprognostic (7.28e-3)" "unprognostic (2.06e-3)" "potential prognostic unfavorable (3.31e-6)" "unprognostic (1.21e-3)" "unprognostic (7.63e-2)" "unprognostic (1.33e-1)" "unprognostic (1.67e-1)" "unprognostic (1.83e-2)" "unprognostic (7.79e-2)" "unprognostic (1.27e-1)" "unprognostic (2.83e-1)" "unprognostic (3.22e-2)" "unprognostic (8.15e-2)" "unprognostic (2.41e-1)" "unprognostic (5.01e-1)" "unprognostic (4.07e-2)" "unprognostic (9.82e-2)" "unprognostic (2.10e-2)" "unprognostic (2.00e-1)" MZT2B "FAM128B, FLJ14346, MOZART2B" ENSG00000152082 "Mitotic spindle organizing protein 2B" Q6NZ67 2 130181737-130190729 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 865.1;Epididymal efferent duct absorptive cells: 990.1;Late spermatids: 2051.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "HPA051758, HPA052623" Approved Supported Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 15: Non-specific - Protein processing" 20 Centrosome "Nucleoplasm, Cytosol" "HPA051758: , HPA052623: " "unprognostic (2.42e-2)" "unprognostic (1.33e-2)" "unprognostic (2.84e-3)" "unprognostic (3.08e-1)" "unprognostic (4.60e-2)" "unprognostic (3.82e-3)" "unprognostic (3.33e-1)" "unprognostic (1.78e-2)" "unprognostic (1.68e-2)" "unprognostic (5.93e-2)" "unprognostic (2.23e-2)" "unprognostic (1.53e-3)" "validated prognostic unfavorable (3.37e-4)" "validated prognostic unfavorable (2.05e-4)" "unprognostic (1.89e-3)" "unprognostic (4.92e-2)" "unprognostic (3.93e-2)" "unprognostic (1.73e-1)" "unprognostic (3.14e-2)" "unprognostic (2.78e-2)" "unprognostic (1.45e-3)" "unprognostic (2.20e-1)" "unprognostic (2.34e-2)" "unprognostic (8.85e-2)" "unprognostic (2.02e-1)" "unprognostic (1.11e-2)" "unprognostic (1.19e-1)" "unprognostic (1.02e-1)" "unprognostic (2.20e-1)" "unprognostic (2.50e-1)" N4BP1 ENSG00000102921 "NEDD4 binding protein 1" O75113 16 48538726-48620148 "Predicted intracellular proteins" "Immunity, Innate immunity" "Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Neutrophils: 2433.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "neutrophil: 8.5" "Lineage enriched" "Detected in many" 5 "granulocytes: 8.5" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 1, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040849, HPA041080" Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" No No "Cluster 21: Neutrophils - Unknown function" "Cluster 58: Skin - Keratinization" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 8 "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "HPA040849: , HPA041080: " "unprognostic (9.16e-2)" "unprognostic (1.23e-1)" "unprognostic (1.54e-1)" "unprognostic (5.59e-2)" "unprognostic (2.04e-1)" "unprognostic (1.59e-1)" "unprognostic (2.40e-1)" "unprognostic (9.30e-2)" "unprognostic (2.62e-1)" "unprognostic (5.49e-3)" "potential prognostic favorable (1.97e-7)" "unprognostic (4.66e-2)" "unprognostic (2.28e-3)" "unprognostic (1.50e-2)" "unprognostic (7.93e-2)" "unprognostic (2.47e-1)" "unprognostic (6.66e-2)" "unprognostic (1.65e-1)" "unprognostic (1.52e-1)" "unprognostic (9.51e-2)" "unprognostic (2.09e-2)" "unprognostic (1.20e-1)" "potential prognostic unfavorable (2.88e-5)" "unprognostic (2.43e-1)" "unprognostic (2.13e-2)" "unprognostic (6.37e-2)" "unprognostic (1.15e-1)" "unprognostic (3.52e-1)" "unprognostic (7.39e-2)" "unprognostic (1.09e-1)" "unprognostic (2.12e-2)" N4BP2 B3BP ENSG00000078177 "NEDD4 binding protein 2" Q86UW6 4 40056797-40158252 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 10.5" "Cell type enhanced" "Detected in many" "Thymocytes: 197.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036770, HPA042607, HPA072549" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 80: Thymus - Adaptive immune response" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" 12 Nucleoplasm "Plasma membrane, Cytosol" "HPA036770: , HPA042607: , HPA072549: " "unprognostic (2.20e-2)" "unprognostic (1.65e-1)" "unprognostic (6.71e-2)" "unprognostic (3.46e-2)" "potential prognostic favorable (6.39e-5)" "unprognostic (3.63e-1)" "unprognostic (1.50e-1)" "unprognostic (3.12e-2)" "unprognostic (1.26e-2)" "unprognostic (1.40e-2)" "unprognostic (2.04e-1)" "unprognostic (2.01e-2)" "unprognostic (8.94e-2)" "unprognostic (2.27e-1)" "unprognostic (5.11e-2)" "unprognostic (7.99e-3)" "unprognostic (2.67e-1)" "unprognostic (9.14e-2)" "unprognostic (5.92e-2)" "unprognostic (1.22e-1)" "unprognostic (1.33e-1)" "unprognostic (9.26e-3)" "potential prognostic unfavorable (1.19e-4)" "unprognostic (3.42e-2)" "unprognostic (2.83e-1)" "unprognostic (7.50e-2)" "unprognostic (1.66e-2)" "unprognostic (2.00e-1)" "unprognostic (2.96e-2)" "unprognostic (1.02e-2)" "unprognostic (5.30e-2)" N4BP2L1 CG018 ENSG00000139597 "NEDD4 binding protein 2 like 1" Q5TBK1 13 32400723-32428311 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 175.4;Hepatocytes: 161.9;pDCs: 237.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Leukemia: 30.6;lymphoma: 15.2;Myeloma: 20.7;Neuroblastoma: 8.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038971, HPA057219" Approved Approved Cytosol NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" Cytosol "HPA038971: , HPA057219: " "potential prognostic favorable (3.24e-5)" "unprognostic (4.70e-3)" "unprognostic (9.92e-2)" "unprognostic (3.60e-2)" "unprognostic (1.04e-1)" "unprognostic (1.67e-3)" "unprognostic (2.13e-1)" "unprognostic (2.72e-2)" "unprognostic (1.28e-1)" "unprognostic (7.51e-3)" "validated prognostic favorable (3.39e-4)" "validated prognostic favorable (5.20e-4)" "unprognostic (1.91e-3)" "unprognostic (2.69e-3)" "unprognostic (1.63e-3)" "unprognostic (2.48e-3)" "unprognostic (8.15e-2)" "unprognostic (1.54e-1)" "unprognostic (4.59e-1)" "unprognostic (3.29e-1)" "unprognostic (1.91e-1)" "unprognostic (3.91e-2)" "unprognostic (7.10e-3)" "unprognostic (2.84e-2)" "unprognostic (1.07e-1)" "unprognostic (2.37e-1)" "unprognostic (1.64e-1)" "unprognostic (3.27e-2)" "unprognostic (1.25e-1)" "unprognostic (4.89e-3)" "unprognostic (2.36e-1)" N4BP2L2 "CG005, PFAAP5" ENSG00000244754 "NEDD4 binding protein 2 like 2" Q92802 13 32432417-32538885 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Myonuclei: 1847.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039338, HPA039434, HPA059327" Approved Approved Nucleoplasm NA NA "Cluster 11: T-cells - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 19: Non-specific - Unknown function" "Cluster 55: Myocytes - Oxidative muscle function" 7 Nucleoplasm "HPA039338: , HPA039434: , HPA059327: " "unprognostic (6.73e-2)" "unprognostic (2.13e-1)" "unprognostic (3.24e-1)" "unprognostic (1.11e-1)" "unprognostic (1.40e-1)" "unprognostic (2.45e-2)" "unprognostic (2.09e-1)" "unprognostic (1.16e-1)" "unprognostic (2.77e-2)" "unprognostic (4.08e-2)" "validated prognostic favorable (4.22e-6)" "validated prognostic favorable (4.99e-4)" "potential prognostic favorable (5.66e-4)" "unprognostic (1.44e-1)" "unprognostic (3.07e-2)" "potential prognostic favorable (3.58e-4)" "unprognostic (1.79e-1)" "unprognostic (1.84e-1)" "unprognostic (2.96e-1)" "unprognostic (5.01e-2)" "unprognostic (8.10e-3)" "unprognostic (1.22e-1)" "unprognostic (6.74e-3)" "unprognostic (1.31e-2)" "unprognostic (2.79e-1)" "unprognostic (4.45e-3)" "unprognostic (6.04e-3)" "unprognostic (2.96e-1)" "unprognostic (5.52e-2)" "unprognostic (1.25e-1)" "unprognostic (2.74e-2)" N4BP3 LZTS4 ENSG00000145911 "NEDD4 binding protein 3" O15049 5 178113532-178126081 "Predicted intracellular proteins" "Immunity, Innate immunity, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 15.3" "Group enriched" "Detected in many" 5 "Esophageal apical cells: 255.7;Esophageal suprabasal cells: 65.9;Extravillous trophoblasts: 202.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory B-cell: 1.7;naive B-cell: 1.6;naive CD8 T-cell: 1.2;plasmacytoid DC: 2.1" "Group enriched" "Detected in many" 16 "B-cells: 1.7;dendritic cells: 2.1;T-cells: 1.2" "Cancer enhanced" "Detected in many" "lymphoma: 12.4" "Breast - Breast glandular cells, Skin - Keratinocyte (granular), Spleen - B-cells (Spleen), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030972, HPA030973, HPA061387" Approved Supported Nucleoplasm,Centrosome NA NA "Cluster 34: B-cells - Unknown function" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 31 Nucleoplasm Centrosome "HPA030972: , HPA030973: , HPA061387: " "unprognostic (3.02e-2)" "unprognostic (6.45e-2)" "unprognostic (1.43e-1)" "unprognostic (4.38e-1)" "unprognostic (5.05e-3)" "unprognostic (6.43e-3)" "unprognostic (3.01e-1)" "unprognostic (7.17e-3)" "unprognostic (4.63e-2)" "unprognostic (1.59e-2)" "unprognostic (5.07e-2)" "unprognostic (6.00e-3)" "unprognostic (1.12e-1)" "unprognostic (1.03e-1)" "unprognostic (1.28e-2)" "unprognostic (2.17e-1)" "unprognostic (1.33e-2)" "unprognostic (1.09e-3)" "unprognostic (8.92e-3)" "unprognostic (3.52e-2)" "unprognostic (1.58e-1)" "unprognostic (3.33e-1)" "unprognostic (2.43e-1)" "unprognostic (1.86e-1)" "unprognostic (8.74e-2)" "unprognostic (3.27e-1)" "unprognostic (1.39e-1)" N6AMT1 "C21orf127, HEMK2, KMT9, MTQ2, N6AMT, PRED28, PrmC" ENSG00000156239 "N-6 adenine-specific DNA methyltransferase 1" Q9Y5N5 21 28872191-28885371 "Predicted intracellular proteins" "Chromatin regulator, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034133, CAB034135, HPA059242" Approved Approved Nucleoplasm,Centrosome Yes No "Cluster 5: Non-specific - Cell proliferation" "Cluster 65: Brain - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 7: Non-specific - Transcription" 1 Nucleoplasm Centrosome "CAB034133: , CAB034135: , HPA059242: " "unprognostic (2.83e-2)" "unprognostic (1.14e-3)" "unprognostic (1.86e-1)" "unprognostic (6.42e-2)" "unprognostic (7.01e-2)" "unprognostic (8.83e-2)" "unprognostic (1.52e-1)" "unprognostic (2.38e-2)" "unprognostic (2.83e-1)" "unprognostic (6.66e-2)" "unprognostic (1.41e-1)" "potential prognostic favorable (9.10e-6)" "unprognostic (3.09e-2)" "unprognostic (3.73e-3)" "unprognostic (8.06e-2)" "unprognostic (8.37e-3)" "unprognostic (7.18e-2)" "unprognostic (7.22e-2)" "unprognostic (2.51e-2)" "unprognostic (3.05e-2)" "unprognostic (1.21e-1)" "unprognostic (1.18e-2)" "unprognostic (1.29e-1)" "unprognostic (1.54e-1)" "potential prognostic favorable (1.40e-4)" "unprognostic (7.13e-2)" "unprognostic (2.66e-1)" "unprognostic (4.47e-3)" "unprognostic (2.62e-1)" "unprognostic (1.95e-1)" "unprognostic (5.89e-3)" NAA10 "ARD1, ARD1A, DXS707, TE2" ENSG00000102030 "N-alpha-acetyltransferase 10, NatA catalytic subunit" P41227 X 153929225-153935080 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Acyltransferase, Transferase" "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Megakaryocytes: 92.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006269, HPA030711" Supported Supported Nucleoli,Cytosol No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 97: Non-specific - Cellular respiration" 76 Cytosol Nucleoli "CAB006269: , HPA030711: " "unprognostic (3.77e-2)" "unprognostic (2.54e-2)" "unprognostic (1.84e-1)" "unprognostic (2.07e-1)" "unprognostic (1.41e-1)" "unprognostic (1.67e-1)" "unprognostic (8.10e-2)" "unprognostic (1.91e-3)" "unprognostic (5.88e-3)" "unprognostic (1.08e-2)" "unprognostic (1.09e-1)" "unprognostic (1.37e-3)" "unprognostic (8.45e-3)" "potential prognostic unfavorable (1.66e-4)" "unprognostic (1.32e-3)" "unprognostic (9.50e-3)" "unprognostic (1.26e-3)" "unprognostic (1.63e-1)" "unprognostic (2.16e-1)" "unprognostic (1.76e-1)" "potential prognostic favorable (3.89e-4)" "unprognostic (7.59e-2)" "unprognostic (2.13e-1)" "unprognostic (9.72e-2)" "unprognostic (4.58e-1)" "unprognostic (1.68e-1)" "unprognostic (2.48e-1)" "unprognostic (4.05e-2)" "unprognostic (2.04e-2)" "unprognostic (4.12e-2)" "unprognostic (1.49e-1)" NAA11 "ARD1B, ARD2, hARD2" ENSG00000156269 "N-alpha-acetyltransferase 11, NatA catalytic subunit" Q9BSU3 4 79225694-79326061 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "placenta: 3.9;testis: 5.8" "Cell type enhanced" "Detected in many" "Astrocytes: 26.0;Cardiomyocytes: 25.8;Cytotrophoblasts: 56.0;Differentiating spermatogonia: 21.9;Early primary spermatocytes: 42.0;Early spermatids: 43.8;Ependymal cells: 36.1;Epicardial cells: 52.3;Extravillous trophoblasts: 29.2;Fibro-adipogenic progenitors: 43.6;Fibroblasts: 30.9;Late primary spermatocytes: 67.6;Late spermatids: 40.4;Migrating cytotrophoblasts: 35.6;Syncytiotrophoblasts: 31.9;Undifferentiated spermatogonia: 26.0;Vascular smooth muscle cells: 33.9" "Group enriched" "Detected in many" 7 "astrocyte: 81.9;ependymal cell: 71.2;fibroblast: 42.7" "Group enriched" "Detected in some" 4 "Bladder Urothelial Carcinoma (TCGA): 1.2;Testicular Germ Cell Tumor (TCGA): 4.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 7.0;thyroid cancer: 7.2" "Testis - Early spermatids" "Not detected" "Not detected" HPA035922 Approved Supported "Nucleoplasm,Golgi apparatus,Primary cilium,Centrosome,Basal body,Cytosol" NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 44: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 28: Astrocytes - Homeostasis & neuron support" 15 "Golgi apparatus, Centrosome, Cytosol" "Nucleoplasm, Primary cilium, Basal body" "HPA035922: " "unprognostic (2.73e-1)" "unprognostic (1.74e-2)" "unprognostic (2.41e-1)" NAA15 "FLJ13340, NARG1, NATH, TBDN100" ENSG00000164134 "N-alpha-acetyltransferase 15, NatA auxiliary subunit" Q9BXJ9 4 139301446-139420033 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Angiogenesis, Differentiation, Transcription, Transcription regulation" "Developmental protein" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023589, HPA050661" Approved Approved "Nuclear bodies,Vesicles,Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Cytosol" Yes NA 59000 "Cluster 14: Non-specific - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 17: Non-specific - RNA processing" 18 Cytosol "Nuclear bodies, Vesicles, Microtubules, Cytokinetic bridge, Mitotic spindle, Primary cilium" "HPA023589: , HPA050661: " "unprognostic (2.53e-1)" "unprognostic (3.57e-2)" "unprognostic (2.73e-1)" "unprognostic (2.36e-3)" "unprognostic (7.12e-3)" "unprognostic (1.67e-1)" "unprognostic (1.99e-1)" "unprognostic (1.91e-1)" "unprognostic (1.52e-1)" "potential prognostic unfavorable (2.50e-4)" "potential prognostic favorable (1.09e-4)" "unprognostic (4.53e-2)" "unprognostic (1.23e-1)" "potential prognostic unfavorable (2.30e-6)" "unprognostic (7.14e-3)" "unprognostic (2.38e-3)" "unprognostic (6.67e-3)" "unprognostic (4.37e-1)" "unprognostic (2.67e-1)" "unprognostic (3.20e-2)" "unprognostic (1.26e-3)" "unprognostic (4.84e-3)" "unprognostic (6.11e-3)" "unprognostic (1.33e-2)" "unprognostic (7.33e-2)" "unprognostic (3.93e-2)" "unprognostic (4.26e-2)" "unprognostic (1.85e-1)" "unprognostic (1.68e-1)" "unprognostic (4.53e-3)" "unprognostic (4.44e-3)" NAA16 "FLJ22054, MGC40612, NARG1L, PRO2435" ENSG00000172766 "N-alpha-acetyltransferase 16, NatA auxiliary subunit" Q6N069 13 41311267-41377030 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 22.1;pancreas: 19.3" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA039761, HPA040157" Approved Enhanced Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 19: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 10 Cytosol "HPA039761: , HPA040157: " "unprognostic (8.03e-3)" "unprognostic (2.07e-2)" "unprognostic (2.49e-1)" "unprognostic (1.11e-1)" "unprognostic (8.17e-2)" "unprognostic (6.62e-2)" "unprognostic (6.89e-2)" "unprognostic (9.73e-3)" "unprognostic (1.80e-1)" "unprognostic (4.13e-3)" "validated prognostic favorable (1.02e-5)" "validated prognostic favorable (4.86e-5)" "unprognostic (1.20e-1)" "unprognostic (8.28e-2)" "unprognostic (7.13e-2)" "unprognostic (1.50e-1)" "unprognostic (4.41e-3)" "unprognostic (2.92e-1)" "unprognostic (4.22e-2)" "unprognostic (9.73e-2)" "unprognostic (1.64e-1)" "unprognostic (3.07e-1)" "unprognostic (2.33e-3)" "unprognostic (8.68e-2)" "unprognostic (4.47e-2)" "unprognostic (2.63e-1)" "unprognostic (1.01e-1)" "unprognostic (1.96e-1)" "unprognostic (1.73e-1)" "unprognostic (7.56e-2)" "unprognostic (3.05e-1)" NAA20 "dJ1002M8.1, NAT3, NAT5" ENSG00000173418 "N-alpha-acetyltransferase 20, NatB catalytic subunit" P61599 20 20017310-20033655 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Acyltransferase, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 1708.5;Esophageal basal cells: 394.4;Esophageal suprabasal cells: 780.6;Hofbauer cells: 430.5;Late primary spermatocytes: 858.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063344 Supported Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 21: Non-specific - Metabolism" "Cluster 62: Non-specific - Plasma proteins" "Cluster 85: Squamous epithelial cells - Keratinization" 5 Cytosol "HPA063344: " "unprognostic (1.37e-2)" "unprognostic (5.70e-3)" "unprognostic (2.14e-1)" "unprognostic (4.27e-2)" "unprognostic (1.76e-1)" "unprognostic (6.22e-2)" "unprognostic (4.48e-3)" "unprognostic (3.20e-2)" "unprognostic (1.57e-3)" "unprognostic (1.89e-1)" "potential prognostic favorable (1.30e-4)" "unprognostic (1.53e-1)" "unprognostic (6.61e-2)" "unprognostic (9.20e-3)" "unprognostic (1.42e-3)" "potential prognostic unfavorable (3.89e-4)" "unprognostic (3.74e-2)" "unprognostic (4.94e-2)" "unprognostic (1.11e-1)" "unprognostic (1.65e-1)" "unprognostic (2.79e-1)" "unprognostic (1.50e-1)" "unprognostic (1.61e-1)" "unprognostic (4.06e-2)" "unprognostic (6.05e-2)" "unprognostic (2.43e-2)" "unprognostic (4.58e-1)" "unprognostic (3.41e-2)" "unprognostic (3.19e-1)" "unprognostic (6.28e-2)" "unprognostic (4.12e-2)" NAA25 "C12orf30, FLJ13089" ENSG00000111300 "N-alpha-acetyltransferase 25, NatB auxiliary subunit" Q14CX7 12 112026689-112108796 "Essential proteins, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 255.7;Cone photoreceptor cells: 242.2;Myonuclei: 248.9;Retinal pigment epithelial cells: 298.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039322 Approved Supported "Golgi apparatus,Cytosol" No No "Cluster 30: Non-specific - DNA binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" 3 "Golgi apparatus, Cytosol" "HPA039322: " "unprognostic (2.86e-1)" "unprognostic (9.31e-3)" "unprognostic (1.35e-2)" "unprognostic (1.49e-2)" "unprognostic (1.05e-1)" "unprognostic (4.53e-2)" "unprognostic (1.63e-1)" "unprognostic (2.96e-2)" "unprognostic (8.02e-2)" "unprognostic (3.91e-2)" "unprognostic (1.04e-2)" "unprognostic (2.69e-3)" "unprognostic (1.31e-1)" "potential prognostic unfavorable (1.29e-5)" "unprognostic (1.26e-2)" "unprognostic (3.62e-3)" "unprognostic (3.22e-3)" "unprognostic (1.66e-1)" "unprognostic (1.19e-1)" "unprognostic (1.28e-1)" "unprognostic (2.37e-3)" "unprognostic (1.92e-2)" "unprognostic (2.16e-3)" "unprognostic (1.31e-2)" "potential prognostic favorable (1.50e-4)" "unprognostic (9.06e-2)" "unprognostic (1.38e-1)" "unprognostic (7.26e-2)" "unprognostic (2.01e-1)" "unprognostic (5.89e-2)" "unprognostic (5.52e-2)" NAA30 "C14orf35, FLJ35355, MAK3, Mak3p, NAT12" ENSG00000139977 "N-alpha-acetyltransferase 30, NatC catalytic subunit" Q147X3 14 57390544-57415906 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 95.0;Late primary spermatocytes: 128.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057824 Uncertain Supported Cytosol NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" 2 Cytosol "HPA057824: " "unprognostic (1.27e-1)" "unprognostic (1.27e-2)" "unprognostic (6.57e-2)" "unprognostic (4.92e-3)" "unprognostic (9.85e-3)" "unprognostic (2.47e-2)" "unprognostic (1.82e-1)" "unprognostic (1.04e-2)" "unprognostic (5.47e-2)" "potential prognostic unfavorable (5.35e-4)" "validated prognostic favorable (4.27e-7)" "validated prognostic favorable (8.41e-4)" "unprognostic (5.61e-2)" "unprognostic (4.67e-3)" "unprognostic (1.85e-1)" "unprognostic (9.91e-3)" "unprognostic (3.60e-1)" "unprognostic (5.11e-2)" "unprognostic (3.05e-2)" "unprognostic (1.82e-2)" "potential prognostic unfavorable (1.06e-5)" "unprognostic (9.36e-2)" "unprognostic (3.00e-2)" "unprognostic (6.17e-2)" "unprognostic (3.18e-1)" "unprognostic (7.34e-3)" "unprognostic (2.68e-1)" "unprognostic (1.25e-1)" "unprognostic (1.59e-1)" "unprognostic (5.09e-3)" "unprognostic (9.69e-2)" NAA35 "bA379P1.1, FLJ21613, FLJ22643, MAK10" ENSG00000135040 "N-alpha-acetyltransferase 35, NatC auxiliary subunit" Q5VZE5 9 85941146-86025462 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021547 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 42: Retina - Visual perception" "Cluster 31: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Transcription" 4 "Nucleoplasm, Plasma membrane, Cytosol" "HPA021547: " "unprognostic (2.55e-1)" "unprognostic (5.16e-2)" "unprognostic (2.99e-1)" "unprognostic (3.48e-2)" "unprognostic (3.04e-1)" "unprognostic (1.20e-1)" "unprognostic (3.10e-2)" "unprognostic (4.31e-3)" "unprognostic (2.56e-1)" "unprognostic (1.46e-2)" "potential prognostic favorable (9.23e-6)" "unprognostic (2.06e-3)" "unprognostic (2.41e-1)" "unprognostic (4.29e-3)" "unprognostic (1.64e-2)" "unprognostic (2.06e-1)" "unprognostic (2.18e-1)" "unprognostic (7.68e-2)" "unprognostic (1.30e-1)" "unprognostic (1.13e-1)" "unprognostic (1.82e-1)" "unprognostic (4.66e-2)" "unprognostic (1.15e-1)" "unprognostic (1.15e-1)" "unprognostic (1.97e-2)" "unprognostic (2.37e-1)" "unprognostic (1.89e-2)" "unprognostic (2.04e-1)" "unprognostic (2.21e-1)" "unprognostic (2.45e-2)" "unprognostic (3.65e-2)" NAA38 "LSMD1, MGC14151, PFAAP2" ENSG00000183011 "N-alpha-acetyltransferase 38, NatC auxiliary subunit" Q9BRA0 17 7856685-7885238 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 803.1;Epicardial cells: 991.5;Late spermatids: 2248.9;Megakaryocytes: 3078.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059189 Supported Nucleoplasm No No "Cluster 10: Non-specific - Membrane trafficking" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 47: Platelets - Hemostasis" 5 Nucleoplasm "HPA059189: " "unprognostic (1.32e-1)" "unprognostic (2.13e-1)" "unprognostic (1.21e-1)" "potential prognostic favorable (6.80e-5)" "unprognostic (1.37e-1)" "unprognostic (4.94e-2)" "unprognostic (2.99e-2)" "unprognostic (8.61e-2)" "unprognostic (1.08e-1)" "unprognostic (1.46e-3)" "unprognostic (1.45e-1)" "unprognostic (1.90e-2)" "unprognostic (6.18e-2)" "unprognostic (9.36e-2)" "unprognostic (1.21e-3)" "unprognostic (2.26e-2)" "unprognostic (2.34e-1)" "unprognostic (4.63e-2)" "unprognostic (3.35e-1)" "unprognostic (1.86e-3)" "unprognostic (2.30e-1)" "potential prognostic favorable (7.81e-4)" "unprognostic (8.14e-2)" "unprognostic (1.15e-1)" "unprognostic (3.35e-1)" "unprognostic (1.99e-2)" "unprognostic (8.53e-2)" "unprognostic (1.73e-1)" "unprognostic (5.54e-2)" "unprognostic (1.53e-1)" "unprognostic (1.75e-1)" NAA40 "FLJ13848, NAT11" ENSG00000110583 "N-alpha-acetyltransferase 40, NatD catalytic subunit" Q86UY6 11 63938959-63957319 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 195.3;Retinal horizontal cells: 106.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037816, HPA056142" Uncertain Supported "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 24: Non-specific - Unknown function" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 31 Nucleoplasm "Centriolar satellite, Cytosol" "HPA037816: , HPA056142: " "unprognostic (9.02e-2)" "unprognostic (9.22e-3)" "unprognostic (2.40e-2)" "unprognostic (9.26e-2)" "unprognostic (7.16e-2)" "unprognostic (1.13e-1)" "unprognostic (2.65e-1)" "unprognostic (1.29e-3)" "unprognostic (7.76e-2)" "unprognostic (3.76e-2)" "unprognostic (3.72e-1)" "unprognostic (2.56e-1)" "unprognostic (1.71e-1)" "potential prognostic unfavorable (1.03e-7)" "unprognostic (4.60e-2)" "unprognostic (6.62e-2)" "unprognostic (2.45e-2)" "unprognostic (3.60e-2)" "unprognostic (2.32e-2)" "unprognostic (4.01e-1)" "unprognostic (2.00e-1)" "unprognostic (1.59e-1)" "unprognostic (3.58e-3)" "unprognostic (3.99e-2)" "unprognostic (1.38e-2)" "unprognostic (8.98e-2)" "unprognostic (6.86e-3)" "unprognostic (3.46e-3)" "unprognostic (1.64e-1)" "unprognostic (7.08e-2)" "unprognostic (2.62e-1)" NAA50 "FLJ13194, MAK3, NAT13, NAT5, San" ENSG00000121579 "N-alpha-acetyltransferase 50, NatE catalytic subunit" Q9GZZ1 3 113716458-113746300 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 259.1" "Cell type enhanced" "Detected in all" "Myonuclei: 355.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074489 Approved Supported Nucleoli NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 12 Nucleoli "HPA074489: " "unprognostic (3.35e-1)" "unprognostic (3.13e-2)" "unprognostic (2.82e-1)" "unprognostic (1.01e-1)" "unprognostic (1.51e-1)" "unprognostic (1.35e-1)" "unprognostic (2.52e-1)" "unprognostic (1.02e-1)" "unprognostic (4.83e-2)" "unprognostic (1.02e-2)" "potential prognostic favorable (5.37e-5)" "unprognostic (1.80e-2)" "unprognostic (6.09e-2)" "unprognostic (3.12e-3)" "unprognostic (2.72e-3)" "potential prognostic unfavorable (1.45e-4)" "unprognostic (8.43e-3)" "unprognostic (2.89e-1)" "unprognostic (1.39e-1)" "unprognostic (4.55e-2)" "unprognostic (9.27e-2)" "potential prognostic unfavorable (3.79e-5)" "unprognostic (3.90e-2)" "unprognostic (1.06e-2)" "unprognostic (3.35e-3)" "unprognostic (3.48e-1)" "unprognostic (7.29e-2)" "unprognostic (3.75e-2)" "unprognostic (8.61e-2)" "unprognostic (2.16e-2)" "unprognostic (1.45e-1)" NAA60 "FLJ14154, HAT4, hNaa60, NAT15, NatF" ENSG00000122390 "N-alpha-acetyltransferase 60, NatF catalytic subunit" Q9H7X0 16 3443649-3486953 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Chromosome partition" "Acyltransferase, Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 17.3;Late primary spermatocytes: 14.8;Late spermatids: 47.1;Megakaryocytes: 18.5;Parietal cells: 19.4;Platelets: 16.9;Podocytes: 16.8;Proximal tubule cells: 17.7;Renal connecting tubule cells: 15.7" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Fibroblasts_2, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040916 Approved Uncertain "Actin filaments,Cytosol" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 25: Non-specific - Transcription" "Cluster 54: Non-specific - Transcription" "Cluster 105: Non-specific - Mixed function" 2 "Actin filaments, Cytosol" "HPA040916: " "unprognostic (1.94e-1)" "unprognostic (3.25e-1)" "unprognostic (3.57e-1)" "unprognostic (3.50e-1)" "unprognostic (1.86e-2)" "unprognostic (3.48e-1)" "unprognostic (2.91e-3)" "unprognostic (2.92e-2)" "unprognostic (7.82e-2)" "potential prognostic favorable (4.38e-4)" "unprognostic (5.75e-2)" "unprognostic (2.94e-2)" "unprognostic (1.18e-2)" "unprognostic (1.96e-1)" "unprognostic (7.51e-2)" "unprognostic (2.01e-1)" "unprognostic (1.26e-3)" "unprognostic (2.28e-1)" "unprognostic (2.82e-1)" "unprognostic (3.20e-2)" "unprognostic (2.99e-2)" "unprognostic (3.88e-1)" "unprognostic (9.94e-2)" "unprognostic (1.88e-2)" "unprognostic (1.20e-1)" "unprognostic (1.43e-1)" "unprognostic (2.08e-1)" "unprognostic (8.86e-2)" "unprognostic (1.40e-1)" NAA80 "FUS2, NAT6" ENSG00000243477 "N-alpha-acetyltransferase 80, NatH catalytic subunit" Q93015 3 50296402-50299416 "Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Deafness, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 59.4" "Group enriched" "Detected in some" 4 "Early spermatids: 1.9;Late spermatids: 7.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "eosinophil: 56.5" "Lineage enriched" "Detected in all" 5 "granulocytes: 56.5" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039576 Approved NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 67: Testis - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" "HPA039576: " "unprognostic (3.54e-2)" "unprognostic (1.49e-2)" "unprognostic (1.62e-1)" "unprognostic (3.16e-3)" "unprognostic (7.01e-2)" "unprognostic (3.85e-2)" "unprognostic (1.37e-1)" "unprognostic (1.15e-1)" "unprognostic (8.65e-2)" "unprognostic (3.39e-2)" "unprognostic (3.36e-2)" "unprognostic (6.23e-3)" "unprognostic (6.84e-2)" "unprognostic (2.76e-2)" "unprognostic (2.90e-1)" "unprognostic (7.77e-2)" "unprognostic (1.13e-1)" "unprognostic (1.27e-1)" "unprognostic (1.41e-1)" "unprognostic (4.84e-2)" "unprognostic (8.30e-2)" "unprognostic (3.06e-1)" "unprognostic (3.48e-2)" "unprognostic (4.42e-3)" "unprognostic (8.41e-2)" "unprognostic (2.03e-1)" "unprognostic (7.71e-2)" "unprognostic (9.19e-2)" "unprognostic (2.35e-1)" NAAA ASAHL ENSG00000138744 "N-acylethanolamine acid amidase" Q02083 4 75913660-75941013 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 322.2;Colonocytes: 161.9;Enterocytes: 233.2;Kupffer cells: 170.1;monocytes: 157.1;Prostatic glandular cells: 265.8" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 4 "Prostate Adenocarcinoma (TCGA): 133.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "intermediate monocyte: 671.9;non-classical monocyte: 585.2" "Lineage enriched" "Detected in all" 5 "monocytes: 671.9" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Prostate - Prostate glandular cells, Spleen - Macrophages, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB026135 Approved "Intracellular and membrane" Enzyme NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" "CAB026135: " "unprognostic (3.76e-3)" "potential prognostic unfavorable (8.34e-4)" "unprognostic (5.48e-2)" "unprognostic (2.46e-1)" "unprognostic (2.82e-2)" "unprognostic (1.37e-1)" "unprognostic (5.56e-2)" "unprognostic (6.83e-3)" "unprognostic (5.76e-2)" "unprognostic (1.64e-2)" "unprognostic (8.15e-3)" "unprognostic (4.52e-1)" "unprognostic (7.10e-3)" "unprognostic (5.02e-2)" "unprognostic (6.80e-3)" "unprognostic (3.67e-1)" "unprognostic (1.59e-1)" "unprognostic (1.58e-1)" "unprognostic (2.38e-1)" "unprognostic (4.66e-3)" "unprognostic (1.83e-1)" "unprognostic (2.20e-2)" "unprognostic (2.16e-1)" "unprognostic (1.97e-1)" "unprognostic (4.87e-2)" "unprognostic (4.24e-1)" "unprognostic (1.10e-1)" "unprognostic (2.67e-1)" "unprognostic (7.83e-2)" "unprognostic (1.40e-3)" "unprognostic (1.28e-2)" NAALAD2 "GCPIII, NAALADASE2" ENSG00000077616 "N-acetylated alpha-linked acidic dipeptidase 2" Q9Y3Q0 11 90131515-90192894 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Carboxypeptidase, Dipeptidase, Hydrolase, Metalloprotease, Multifunctional enzyme, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 18.8;testis: 13.3" "Cell type enhanced" "Detected in some" "Bergmann glia: 37.7;Brain excitatory neurons: 61.3;Brain inhibitory neurons: 125.2;Early spermatids: 35.7;Ependymal cells: 19.6;Late spermatids: 19.9;Oligodendrocyte progenitor cells: 148.8;Oligodendrocytes: 55.4;Other brain neurons: 65.4" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Glioblastoma Multiforme (TCGA): 1.1;Testicular Germ Cell Tumor (TCGA): 2.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 5.0" "Kidney - Fibroblasts, Minor Salivary Gland - Fibroblasts, Pituitary gland - Lactotropes, Prostate - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA060820, HPA065419" Approved Approved Nucleoplasm NA NA "Cluster 75: Ovary - Mixed function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 34: Testis cancer - Unknown function" "Cluster 109: Neurons - Neuronal signaling" 4 Nucleoplasm "HPA060820: , HPA065419: " "unprognostic (2.08e-1)" "unprognostic (5.13e-2)" "unprognostic (2.35e-3)" "unprognostic (1.16e-3)" "unprognostic (3.26e-1)" "unprognostic (1.76e-1)" NAALADL1 HILAP ENSG00000168060 "N-acetylated alpha-linked acidic dipeptidase like 1" Q9UQQ1 11 65044818-65058553 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "intestine: 96.2" "Cell type enriched" "Detected in many" 24 "Enterocytes: 610.1" "Cell type enhanced" "Detected in some" "endothelial cell: 9.2;leukocyte: 6.2;pericyte: 6.6;vascular associated smooth muscle cell: 5.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 183.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Adrenal gland - Endothelial cells, Liver - Vascular endothelial cells, Prostate - Fibroblasts, Stomach - Fibroblasts, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA047123 Enhanced Uncertain Cytosol NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 77: Intestine - Digestion" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 1: Enterocytes - Absorption and Digestion" Cytosol "HPA047123: " "unprognostic (1.44e-2)" "unprognostic (2.36e-2)" "unprognostic (2.50e-1)" "unprognostic (8.03e-3)" "unprognostic (1.36e-1)" "unprognostic (3.07e-1)" "unprognostic (1.15e-2)" "unprognostic (2.27e-2)" "unprognostic (3.94e-3)" "unprognostic (4.02e-2)" "unprognostic (2.55e-3)" "unprognostic (2.64e-2)" "unprognostic (6.39e-2)" "unprognostic (7.92e-2)" "unprognostic (2.30e-3)" "unprognostic (2.30e-2)" "unprognostic (4.29e-2)" "unprognostic (9.01e-2)" "unprognostic (8.88e-2)" "unprognostic (2.11e-1)" "unprognostic (5.76e-2)" "unprognostic (3.27e-1)" "unprognostic (2.07e-1)" "unprognostic (1.49e-1)" "unprognostic (2.94e-3)" "unprognostic (1.50e-1)" "unprognostic (1.29e-1)" "unprognostic (2.92e-3)" "unprognostic (6.85e-2)" "unprognostic (2.78e-1)" "unprognostic (5.72e-2)" NAALADL2 ENSG00000177694 "N-acetylated alpha-linked acidic dipeptidase like 2" Q58DX5 3 174438573-175810548 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 1264.6;Renal connecting tubule cells: 1615.5;Salivary acinar cells: 1320.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 10.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 4.9" "Breast - Breast myoepithelial cells, Kidney - Fibroblasts, Liver - Hepatocytes, Skeletal muscle - Fibroblasts, Testis - Early spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA012413, HPA017425, CAB025586" Approved Enhanced Nucleoplasm NA NA "Cluster 38: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 5 Nucleoplasm "CAB025586: , HPA012413: , HPA017425: " "unprognostic (2.95e-3)" "unprognostic (1.75e-1)" "unprognostic (1.48e-1)" "unprognostic (6.41e-2)" "unprognostic (9.29e-3)" "unprognostic (3.37e-2)" "unprognostic (3.32e-1)" "unprognostic (5.09e-2)" "unprognostic (1.25e-2)" "potential prognostic favorable (8.88e-8)" "unprognostic (1.94e-1)" "unprognostic (5.29e-3)" "potential prognostic unfavorable (4.63e-4)" "unprognostic (3.13e-2)" "unprognostic (3.19e-2)" "unprognostic (8.24e-2)" "unprognostic (3.73e-2)" "unprognostic (4.85e-2)" "unprognostic (1.30e-2)" "unprognostic (2.24e-1)" "unprognostic (4.00e-2)" "unprognostic (1.73e-1)" "unprognostic (2.90e-1)" "unprognostic (3.37e-2)" "unprognostic (1.47e-1)" "unprognostic (9.27e-2)" "unprognostic (2.48e-1)" NAB1 ENSG00000138386 "NGFI-A binding protein 1" Q13506 2 190646746-190692766 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epicardial cells: 134.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002738 Uncertain Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 22: Epididymis - Mixed function" "Cluster 16: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 3 "Nucleoplasm, Plasma membrane" "Golgi apparatus" "HPA002738: " "unprognostic (1.42e-1)" "unprognostic (2.24e-1)" "unprognostic (5.47e-2)" "unprognostic (3.31e-3)" "unprognostic (7.49e-2)" "potential prognostic unfavorable (7.05e-6)" "unprognostic (6.54e-2)" "unprognostic (2.05e-2)" "unprognostic (6.19e-2)" "unprognostic (6.03e-3)" "unprognostic (1.08e-3)" "potential prognostic favorable (3.40e-5)" "unprognostic (2.09e-1)" "unprognostic (1.35e-2)" "unprognostic (1.21e-1)" "unprognostic (3.46e-2)" "unprognostic (1.01e-1)" "unprognostic (1.04e-1)" "unprognostic (3.76e-2)" "unprognostic (5.42e-2)" "unprognostic (8.47e-2)" "potential prognostic unfavorable (7.44e-4)" "unprognostic (4.16e-2)" "unprognostic (2.13e-1)" "unprognostic (3.29e-1)" "unprognostic (2.82e-1)" "unprognostic (3.91e-2)" "unprognostic (7.32e-2)" "unprognostic (1.27e-1)" "unprognostic (2.07e-2)" "unprognostic (9.68e-2)" NAB2 MADER ENSG00000166886 "NGFI-A binding protein 2" Q15742 12 57089043-57095476 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 50.0;Syncytiotrophoblasts: 61.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004510, HPA027464" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 83 "Nucleoplasm, Cytosol" "CAB004510: , HPA027464: " "unprognostic (4.10e-1)" "unprognostic (9.88e-3)" "unprognostic (1.11e-1)" "unprognostic (2.43e-1)" "unprognostic (7.74e-3)" "unprognostic (8.28e-2)" "unprognostic (1.03e-1)" "unprognostic (1.91e-1)" "unprognostic (1.34e-1)" "unprognostic (3.79e-1)" "unprognostic (1.20e-2)" "unprognostic (3.60e-2)" "unprognostic (4.01e-2)" "potential prognostic unfavorable (7.98e-4)" "unprognostic (7.93e-2)" "unprognostic (5.12e-2)" "unprognostic (4.91e-2)" "unprognostic (3.91e-1)" "unprognostic (7.28e-2)" "unprognostic (1.78e-1)" "unprognostic (1.90e-1)" "unprognostic (2.11e-1)" "unprognostic (1.96e-2)" "unprognostic (8.38e-2)" "unprognostic (3.58e-2)" "unprognostic (2.50e-3)" "unprognostic (2.48e-1)" "unprognostic (2.95e-1)" "unprognostic (8.33e-2)" "unprognostic (3.32e-2)" "unprognostic (1.14e-1)" NABP1 "DKFZp667M1322, FLJ13624, FLJ22833, hSSB2, MGC111163, NABP1-OT1, OBFC2A, SOSS-B2, SSB2" ENSG00000173559 "Nucleic acid binding protein 1" Q96AH0 2 191678068-191741097 "Predicted intracellular proteins" "DNA damage, DNA repair" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Neutrophils: 2644.4" "Group enriched" "Detected in all" 6 "central nervous system macrophage: 115.3;leukocyte: 145.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Neutrophils, Minor Salivary Gland - Mitotic cells (Minor salivary gland), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054978, HPA067802" Enhanced Nucleoplasm,Cytosol NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 12 Nucleoplasm Cytosol "HPA054978: , HPA067802: " "unprognostic (1.15e-1)" "unprognostic (2.34e-2)" "potential prognostic unfavorable (4.86e-4)" "unprognostic (2.08e-2)" "unprognostic (2.18e-2)" "unprognostic (1.73e-2)" "unprognostic (2.33e-2)" "unprognostic (1.44e-2)" "unprognostic (4.54e-1)" "unprognostic (3.56e-3)" "unprognostic (3.64e-2)" "unprognostic (7.90e-2)" "potential prognostic unfavorable (9.22e-4)" "unprognostic (2.59e-2)" "unprognostic (4.19e-2)" "unprognostic (1.74e-1)" "unprognostic (3.35e-1)" "unprognostic (1.42e-1)" "unprognostic (3.25e-1)" "unprognostic (2.73e-2)" "potential prognostic unfavorable (1.28e-4)" "unprognostic (3.98e-2)" "unprognostic (2.53e-1)" "potential prognostic favorable (2.96e-4)" "unprognostic (1.81e-2)" "unprognostic (9.25e-2)" "unprognostic (1.77e-1)" "unprognostic (3.54e-1)" "unprognostic (2.88e-2)" NABP2 "hSSB1, MGC2731, OBFC2B, SOSS-B1, SSB1" ENSG00000139579 "Nucleic acid binding protein 2" Q9BQ15 12 56222015-56229854 "Predicted intracellular proteins" "DNA damage, DNA repair" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Late spermatids: 428.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044615, HPA057213" Supported Enhanced Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 38: Non-specific - Transcription" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 21 Nucleoplasm "HPA044615: , HPA057213: " "unprognostic (9.91e-2)" "unprognostic (1.08e-2)" "unprognostic (1.17e-1)" "unprognostic (2.09e-1)" "unprognostic (5.43e-2)" "unprognostic (6.39e-2)" "potential prognostic favorable (4.70e-4)" "unprognostic (9.53e-2)" "potential prognostic unfavorable (5.28e-5)" "unprognostic (4.39e-2)" "unprognostic (1.35e-1)" "unprognostic (4.29e-1)" "potential prognostic unfavorable (3.43e-7)" "unprognostic (1.28e-2)" "potential prognostic unfavorable (9.91e-4)" "unprognostic (1.55e-2)" "unprognostic (2.35e-1)" "unprognostic (3.34e-2)" "unprognostic (5.50e-2)" "unprognostic (2.37e-1)" "unprognostic (9.79e-2)" "unprognostic (1.68e-2)" "unprognostic (4.97e-2)" "unprognostic (1.59e-2)" "unprognostic (1.30e-2)" "unprognostic (2.84e-2)" "unprognostic (8.96e-2)" "unprognostic (3.14e-1)" "unprognostic (1.16e-1)" NACA NACA1 ENSG00000196531 "Nascent polypeptide associated complex subunit alpha" "E9PAV3, Q13765" 12 56712305-56731628 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transcription, Transcription regulation, Transport" "Activator, Chaperone, DNA-binding" Allergen "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 7146.6;Esophageal basal cells: 4475.5;Esophageal suprabasal cells: 5430.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA073152, HPA073648" Approved Cytosol NA Yes 1600000 "Cluster 13: Non-specific - Mitochondria" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 35 Cytosol "HPA073152: , HPA073648: " "unprognostic (2.70e-1)" "unprognostic (1.45e-1)" "unprognostic (2.76e-2)" "unprognostic (7.84e-3)" "unprognostic (7.13e-2)" "unprognostic (9.30e-2)" "unprognostic (9.71e-2)" "unprognostic (9.72e-3)" "unprognostic (1.87e-2)" "unprognostic (3.90e-3)" "unprognostic (8.47e-3)" "unprognostic (2.42e-2)" "potential prognostic unfavorable (5.77e-5)" "validated prognostic unfavorable (1.27e-5)" "validated prognostic unfavorable (1.04e-5)" "validated prognostic unfavorable (6.20e-5)" "validated prognostic unfavorable (9.51e-6)" "unprognostic (3.77e-2)" "unprognostic (9.57e-2)" "unprognostic (6.12e-2)" "unprognostic (1.30e-1)" "unprognostic (1.70e-2)" "unprognostic (3.85e-1)" "unprognostic (9.25e-2)" "unprognostic (4.27e-2)" "unprognostic (1.35e-1)" "unprognostic (1.25e-1)" "unprognostic (1.60e-3)" "unprognostic (2.05e-1)" "unprognostic (1.07e-1)" "potential prognostic favorable (3.94e-4)" NACA2 "MGC71999, NACAL" ENSG00000253506 "Nascent polypeptide associated complex subunit alpha 2" Q9H009 17 61590421-61591219 "Essential proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 29 "testis: 59.5" "Group enriched" "Detected in many" 15 "Early spermatids: 371.3;Late primary spermatocytes: 658.0;Late spermatids: 167.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "HPA073152, HPA073648" Approved Cytosol NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 6: Testis - Spermatogenesis" "Cluster 61: BICR 18 - Protein kinases" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 7 Cytosol "HPA073152: , HPA073648: " "unprognostic (5.27e-2)" NACAD KIAA0363 ENSG00000136274 "NAC alpha domain containing" O15069 7 45080437-45088969 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 63.4;pituitary gland: 22.9" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 10.6;Brain inhibitory neurons: 9.4;Gonadotrophs: 15.1;Lactotrophs: 12.2;Oligodendrocytes: 40.2;Other brain neurons: 18.1;Peritubular myoid cells: 11.1;Retinal horizontal cells: 14.0;Thyrotrophs: 9.5" "Cell type enhanced" "Detected in all" "oligodendrocyte: 49.7" "Group enriched" "Detected in many" 5 "Glioblastoma Multiforme (TCGA): 25.7;Testicular Germ Cell Tumor (TCGA): 30.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "Neuroblastoma: 25.4" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal medulla cells, Pituitary gland - Lactotropes, Prostate - Fibroblasts, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020981, HPA079208" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 6: Non-specific - Immune response" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 80: Oligodendrocytes - Myelination" 3 Cytosol Nucleoplasm "HPA020981: , HPA079208: " "unprognostic (1.02e-2)" "unprognostic (1.34e-3)" "unprognostic (4.30e-1)" "unprognostic (1.01e-1)" "potential prognostic unfavorable (6.25e-4)" "unprognostic (2.21e-2)" "unprognostic (2.19e-1)" "unprognostic (1.66e-1)" "unprognostic (1.34e-2)" "unprognostic (7.04e-2)" "unprognostic (1.63e-2)" "unprognostic (6.97e-2)" "unprognostic (1.10e-1)" "unprognostic (3.46e-2)" "unprognostic (1.07e-1)" "unprognostic (3.98e-2)" "unprognostic (6.47e-2)" "unprognostic (4.44e-3)" "unprognostic (3.19e-1)" "unprognostic (1.27e-2)" "unprognostic (5.47e-2)" "unprognostic (2.53e-2)" "unprognostic (1.27e-2)" "unprognostic (3.51e-2)" "unprognostic (2.88e-1)" "unprognostic (1.18e-2)" NACC1 "BEND8, BTBD14B, BTBD30, NAC-1, NAC1" ENSG00000160877 "Nucleus accumbens associated 1" Q96RE7 19 13116862-13141147 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 57.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021238, HPA062245, CAB069927" Enhanced Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 68: Non-specific - Basic cellular processes" "Cluster 51: Neurons - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 81: Alveolar cells - Lung function" 27 Nucleoplasm "Vesicles, Cytosol" "CAB069927: , HPA021238: , HPA062245: " "unprognostic (5.84e-2)" "unprognostic (3.05e-2)" "unprognostic (3.39e-1)" "unprognostic (5.41e-2)" "unprognostic (2.24e-2)" "unprognostic (1.14e-1)" "unprognostic (4.28e-1)" "unprognostic (1.69e-1)" "unprognostic (1.61e-1)" "unprognostic (2.49e-2)" "unprognostic (5.90e-2)" "potential prognostic unfavorable (9.36e-4)" "unprognostic (2.15e-1)" "unprognostic (1.34e-2)" "unprognostic (2.60e-2)" "unprognostic (3.36e-3)" "unprognostic (1.92e-2)" "unprognostic (1.53e-1)" "unprognostic (4.17e-2)" "unprognostic (2.51e-1)" "unprognostic (8.21e-2)" "unprognostic (1.91e-2)" "unprognostic (1.32e-1)" "unprognostic (3.72e-2)" "unprognostic (1.35e-1)" "unprognostic (1.48e-1)" "unprognostic (7.69e-3)" "unprognostic (8.23e-3)" "unprognostic (1.64e-1)" "unprognostic (2.65e-1)" "unprognostic (3.03e-2)" NACC2 "BEND9, BTBD14A, BTBD31, MGC23427" ENSG00000148411 "NACC family member 2" Q96BF6 9 136006537-136095289 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 62.3" "Cell type enhanced" "Detected in many" "Late spermatids: 456.1;Neutrophils: 120.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast), Prostate - Smooth muscle cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047924, HPA052962" Approved Approved Nucleoli,Mitochondria NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 20 "Nucleoli, Mitochondria" "HPA047924: , HPA052962: " "unprognostic (5.04e-2)" "unprognostic (1.67e-2)" "unprognostic (1.41e-1)" "unprognostic (5.34e-2)" "unprognostic (7.61e-2)" "unprognostic (1.65e-1)" "unprognostic (2.95e-1)" "unprognostic (2.94e-3)" "unprognostic (2.14e-1)" "unprognostic (2.34e-1)" "potential prognostic favorable (4.38e-4)" "unprognostic (1.10e-2)" "unprognostic (7.58e-3)" "unprognostic (1.05e-2)" "unprognostic (5.03e-2)" "unprognostic (7.98e-2)" "unprognostic (6.78e-2)" "unprognostic (1.63e-3)" "unprognostic (4.11e-1)" "unprognostic (5.40e-2)" "unprognostic (2.07e-1)" "unprognostic (1.21e-2)" "unprognostic (2.01e-1)" "unprognostic (4.69e-2)" "unprognostic (1.22e-1)" "unprognostic (8.77e-2)" "unprognostic (2.90e-1)" "unprognostic (3.03e-2)" "unprognostic (1.66e-1)" "unprognostic (4.37e-2)" "unprognostic (1.68e-1)" NADK FLJ13052 ENSG00000008130 "NAD kinase" O95544 1 1751232-1780457 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Neutrophil progenitors: 191.4;Neutrophils: 342.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 507.6" "Group enriched" "Detected in all" 7 "granulocytes: 507.6;monocytes: 163.3" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048909, HPA053368" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 27: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 21 Nucleoplasm Cytosol "HPA048909: , HPA053368: " "unprognostic (4.01e-2)" "unprognostic (1.38e-1)" "unprognostic (2.10e-2)" "unprognostic (5.56e-2)" "unprognostic (2.91e-2)" "unprognostic (8.04e-3)" "unprognostic (1.36e-1)" "unprognostic (1.28e-1)" "unprognostic (3.31e-2)" "unprognostic (1.82e-1)" "unprognostic (1.07e-1)" "unprognostic (8.26e-2)" "unprognostic (8.86e-3)" "unprognostic (2.19e-1)" "unprognostic (6.65e-3)" "unprognostic (1.87e-1)" "unprognostic (4.74e-1)" "unprognostic (5.72e-2)" "unprognostic (3.71e-1)" "unprognostic (6.87e-2)" "potential prognostic favorable (1.61e-4)" "unprognostic (3.37e-1)" "unprognostic (2.13e-1)" "unprognostic (4.16e-1)" "unprognostic (2.07e-1)" "unprognostic (2.17e-1)" "unprognostic (2.37e-2)" "unprognostic (1.65e-1)" "unprognostic (2.25e-1)" "unprognostic (1.63e-2)" "unprognostic (3.10e-1)" NADK2 "C5orf33, FLJ30596, MNADK, NADKD1" ENSG00000152620 "NAD kinase 2, mitochondrial" Q4G0N4 5 36192589-36242279 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 11 "liver: 306.9" "Cell type enhanced" "Detected in many" "Astrocytes: 146.0;Early spermatids: 336.6;Ependymal cells: 192.6;Hepatocytes: 293.9;Late primary spermatocytes: 237.4;Late spermatids: 213.4" "Cell type enhanced" "Detected in all" "ependymal cell: 205.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038366, HPA038367, HPA061492" Enhanced Supported Mitochondria NA NA 31000 "Cluster 20: Non-specific - DNA binding" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 39: Astrocytes - Mixed function" "Cluster 29: Non-specific - Unknown function" "Cluster 28: Astrocytes - Homeostasis & neuron support" 2 Mitochondria "HPA038366: , HPA038367: , HPA061492: " "unprognostic (5.81e-3)" "unprognostic (1.00e-2)" "unprognostic (1.39e-1)" "unprognostic (5.93e-3)" "unprognostic (1.59e-1)" "unprognostic (1.16e-1)" "unprognostic (7.39e-2)" "unprognostic (8.29e-2)" "unprognostic (1.72e-2)" "potential prognostic favorable (1.29e-8)" "unprognostic (5.54e-3)" "unprognostic (1.01e-1)" "unprognostic (3.51e-2)" "unprognostic (7.06e-2)" "unprognostic (1.23e-1)" "unprognostic (1.45e-1)" "unprognostic (1.48e-3)" "unprognostic (2.64e-1)" "unprognostic (5.87e-2)" "unprognostic (4.49e-3)" "unprognostic (1.24e-2)" "unprognostic (1.46e-1)" "unprognostic (1.36e-2)" "unprognostic (2.46e-1)" "unprognostic (3.40e-1)" "unprognostic (2.90e-2)" "unprognostic (1.19e-1)" "unprognostic (1.29e-2)" "unprognostic (9.90e-2)" NADSYN1 FLJ10631 ENSG00000172890 "NAD synthetase 1" Q6IA69 11 71453109-71524107 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Ligase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017798, HPA038523, HPA038524" Approved Approved "Golgi apparatus,Vesicles,Cytosol" NA NA 8100 "Cluster 2: Dendritic cells - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 24: Non-specific - Unknown function" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 14 Vesicles "Golgi apparatus, Cytosol" "CAB017798: , HPA038523: , HPA038524: " "unprognostic (9.24e-2)" "unprognostic (2.61e-1)" "unprognostic (8.82e-3)" "unprognostic (6.06e-2)" "unprognostic (2.17e-1)" "unprognostic (8.22e-2)" "unprognostic (1.73e-1)" "unprognostic (1.30e-2)" "unprognostic (1.53e-2)" "potential prognostic unfavorable (7.49e-5)" "unprognostic (2.18e-1)" "unprognostic (4.65e-1)" "unprognostic (5.47e-3)" "potential prognostic unfavorable (7.02e-6)" "unprognostic (3.26e-1)" "unprognostic (1.03e-1)" "unprognostic (2.04e-1)" "unprognostic (1.80e-2)" "unprognostic (1.55e-1)" "unprognostic (2.37e-2)" "unprognostic (1.04e-1)" "unprognostic (1.40e-1)" "unprognostic (9.10e-3)" "unprognostic (1.02e-2)" "unprognostic (6.89e-2)" "unprognostic (1.99e-1)" "unprognostic (2.25e-1)" "unprognostic (1.30e-2)" "unprognostic (2.52e-2)" "unprognostic (1.58e-2)" "unprognostic (1.34e-1)" NAE1 "APP-BP1, APPBP1, ula-1" ENSG00000159593 "NEDD8 activating enzyme E1 subunit 1" Q13564 16 66802875-66873256 "Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, Ubl conjugation pathway" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Differentiating spermatogonia: 235.8;Early primary spermatocytes: 213.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "HPA041178, HPA042041" Enhanced Approved Nucleoplasm,Microtubules,Centrosome NA NA 140000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 26 Nucleoplasm "Microtubules, Centrosome" "HPA041178: , HPA042041: " "unprognostic (2.63e-1)" "unprognostic (6.39e-3)" "unprognostic (4.79e-1)" "unprognostic (4.31e-2)" "unprognostic (2.30e-1)" "unprognostic (3.20e-2)" "unprognostic (1.13e-2)" "unprognostic (1.06e-2)" "unprognostic (3.56e-2)" "unprognostic (7.14e-2)" "unprognostic (2.12e-1)" "unprognostic (1.77e-1)" "unprognostic (7.39e-2)" "validated prognostic unfavorable (1.35e-11)" "validated prognostic unfavorable (5.78e-4)" "unprognostic (2.45e-1)" "unprognostic (6.14e-2)" "unprognostic (3.16e-2)" "unprognostic (2.84e-2)" "unprognostic (3.03e-2)" "unprognostic (1.02e-2)" "unprognostic (7.41e-3)" "unprognostic (2.10e-1)" "unprognostic (1.01e-1)" "unprognostic (9.17e-3)" "unprognostic (9.29e-2)" "unprognostic (4.13e-3)" "unprognostic (6.30e-2)" "unprognostic (1.83e-1)" "unprognostic (4.69e-3)" "unprognostic (1.56e-1)" NAF1 ENSG00000145414 "Nuclear assembly factor 1 ribonucleoprotein" Q96HR8 4 163110073-163166890 "Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epicardial cells: 159.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036241, HPA036242, HPA066090" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 29: Forebrain - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 103: Non-specific - Basic cellular processes" 32 Nucleoplasm Cytosol "HPA036241: , HPA036242: , HPA066090: " "unprognostic (1.87e-1)" "unprognostic (3.11e-1)" "unprognostic (9.64e-2)" "unprognostic (7.89e-2)" "unprognostic (4.00e-3)" "unprognostic (3.20e-2)" "unprognostic (1.22e-1)" "unprognostic (7.49e-2)" "unprognostic (3.04e-1)" "unprognostic (1.55e-1)" "validated prognostic favorable (2.50e-7)" "validated prognostic favorable (3.07e-5)" "unprognostic (4.37e-2)" "unprognostic (1.76e-2)" "unprognostic (2.94e-1)" "unprognostic (1.79e-2)" "potential prognostic unfavorable (3.29e-4)" "unprognostic (1.13e-1)" "unprognostic (1.86e-1)" "unprognostic (3.31e-2)" "unprognostic (4.75e-2)" "unprognostic (8.49e-3)" "potential prognostic unfavorable (6.46e-4)" "unprognostic (1.28e-1)" "unprognostic (5.77e-3)" "unprognostic (9.75e-2)" "unprognostic (4.96e-2)" "unprognostic (3.01e-1)" "unprognostic (4.66e-1)" "unprognostic (5.37e-2)" "unprognostic (4.71e-2)" NAGA D22S674 ENSG00000198951 Alpha-N-acetylgalactosaminidase P17050 22 42058334-42070842 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" "Glycosidase, Hydrolase" "Cancer-related genes, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 54.1;Extravillous trophoblasts: 90.5;Hofbauer cells: 116.9;Kupffer cells: 60.5;monocytes: 60.1;Syncytiotrophoblasts: 65.7" "Cell type enriched" "Detected in all" 4 "central nervous system macrophage: 41.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "classical monocyte: 202.7;intermediate monocyte: 249.1;myeloid DC: 195.3;non-classical monocyte: 259.0;plasmacytoid DC: 120.0" "Group enriched" "Detected in all" 6 "dendritic cells: 195.3;monocytes: 259.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000649 Enhanced "Intracellular and membrane" Enzyme NA NA 1500000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 24 "HPA000649: " "unprognostic (9.90e-2)" "unprognostic (1.65e-1)" "unprognostic (5.66e-2)" "unprognostic (2.49e-1)" "unprognostic (6.62e-2)" "unprognostic (2.08e-2)" "unprognostic (6.82e-2)" "unprognostic (3.23e-1)" "unprognostic (1.64e-1)" "unprognostic (5.81e-3)" "potential prognostic favorable (3.28e-5)" "unprognostic (1.13e-1)" "unprognostic (1.29e-1)" "unprognostic (5.07e-2)" "unprognostic (1.61e-2)" "unprognostic (3.74e-1)" "unprognostic (4.65e-2)" "unprognostic (1.79e-1)" "unprognostic (9.28e-2)" "unprognostic (7.26e-3)" "unprognostic (8.53e-2)" "unprognostic (2.94e-2)" "unprognostic (3.47e-2)" "unprognostic (9.65e-2)" "unprognostic (2.97e-3)" "unprognostic (7.03e-2)" "unprognostic (7.87e-2)" "unprognostic (1.95e-1)" "unprognostic (1.74e-2)" "unprognostic (2.26e-1)" "unprognostic (5.20e-2)" NAGK GNK ENSG00000124357 "N-acetylglucosamine kinase" Q9UJ70 2 71064344-71079808 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Immunity, Innate immunity" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 458.9;Esophageal suprabasal cells: 293.8;Hofbauer cells: 227.0;Late primary spermatocytes: 180.1;Syncytiotrophoblasts: 342.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 392.0;granulocytes: 289.2;monocytes: 594.4" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035206, HPA035207" Enhanced Approved Nucleoplasm,Cytosol NA NA 640000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 45: Non-specific - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 85: Squamous epithelial cells - Keratinization" 31 Cytosol Nucleoplasm "HPA035206: , HPA035207: " "unprognostic (2.73e-3)" "unprognostic (7.42e-3)" "unprognostic (1.09e-1)" "unprognostic (5.17e-3)" "unprognostic (7.24e-2)" "unprognostic (1.67e-1)" "unprognostic (2.20e-1)" "unprognostic (9.95e-3)" "unprognostic (4.26e-2)" "unprognostic (2.71e-1)" "unprognostic (1.49e-3)" "unprognostic (3.17e-3)" "unprognostic (1.02e-1)" "potential prognostic unfavorable (5.56e-4)" "unprognostic (1.24e-1)" "unprognostic (6.31e-2)" "unprognostic (2.59e-2)" "unprognostic (2.85e-1)" "unprognostic (3.01e-2)" "unprognostic (5.10e-1)" "unprognostic (1.72e-1)" "unprognostic (1.28e-1)" "unprognostic (2.43e-2)" "unprognostic (5.43e-2)" "unprognostic (5.59e-2)" "unprognostic (2.04e-1)" "unprognostic (3.21e-1)" "unprognostic (1.33e-1)" "unprognostic (4.07e-2)" "unprognostic (3.39e-2)" "unprognostic (3.26e-1)" NAGLU NAG ENSG00000108784 N-acetyl-alpha-glucosaminidase P54802 17 42536241-42544449 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Charcot-Marie-Tooth disease, Disease variant, Mucopolysaccharidosis, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 7 "Distal convoluted tubule cells: 14.6;Loop of henle epithelial cells: 17.3;Papillary tip epithelial cells: 14.4;Podocytes: 21.4;Proximal tubule cells: 40.6;Renal collecting duct intercalated cells: 12.6;Renal collecting duct principal cells: 13.3;Renal connecting tubule cells: 10.3" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells, Skin - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038815 Supported "Intracellular and membrane" Enzyme NA NA 64000000 "Cluster 22: Eosinophils - Transcription" "Cluster 70: Non-specific - Protein processing" "Cluster 11: White matter - Signal transduction" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 88: Proximal tubular cells - Transmembrane transport" 31 "HPA038815: " "unprognostic (5.36e-2)" "unprognostic (1.18e-1)" "unprognostic (7.64e-2)" "unprognostic (8.71e-2)" "unprognostic (1.14e-2)" "unprognostic (6.87e-3)" "unprognostic (2.18e-2)" "unprognostic (3.91e-1)" "unprognostic (5.68e-2)" "unprognostic (6.03e-2)" "potential prognostic favorable (1.08e-4)" "unprognostic (9.18e-2)" "unprognostic (2.70e-3)" "unprognostic (1.31e-2)" "unprognostic (3.36e-1)" "unprognostic (6.76e-2)" "unprognostic (2.46e-1)" "unprognostic (1.19e-1)" "unprognostic (1.93e-1)" "unprognostic (1.23e-1)" "unprognostic (1.21e-1)" "unprognostic (3.70e-3)" "unprognostic (2.94e-1)" "unprognostic (8.18e-2)" "unprognostic (1.22e-1)" "unprognostic (9.91e-2)" "unprognostic (1.11e-1)" "unprognostic (8.31e-2)" "unprognostic (6.47e-2)" "unprognostic (2.30e-2)" "unprognostic (1.02e-3)" NAGPA "APAA, UCE" ENSG00000103174 "N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase" Q9UK23 16 5024844-5034141 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 38.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064055 Approved NA NA 3100000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 51: Neurons - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 35: Neurons - Synaptic function & neurogenesis" "HPA064055: " "unprognostic (8.45e-3)" "unprognostic (3.23e-2)" "unprognostic (1.87e-1)" "unprognostic (1.93e-2)" "unprognostic (1.81e-1)" "unprognostic (1.81e-1)" "unprognostic (1.16e-2)" "unprognostic (8.55e-2)" "unprognostic (7.25e-2)" "unprognostic (9.33e-3)" "potential prognostic unfavorable (3.09e-5)" "unprognostic (1.40e-2)" "unprognostic (1.03e-1)" "potential prognostic unfavorable (4.93e-4)" "unprognostic (1.50e-2)" "unprognostic (4.31e-2)" "unprognostic (1.55e-1)" "unprognostic (6.87e-2)" "unprognostic (8.69e-2)" "unprognostic (1.17e-1)" "unprognostic (4.04e-2)" "unprognostic (6.72e-3)" "unprognostic (1.48e-1)" "unprognostic (2.91e-1)" "unprognostic (1.16e-1)" "unprognostic (7.61e-2)" "unprognostic (1.81e-1)" "unprognostic (1.88e-1)" "unprognostic (1.73e-2)" "unprognostic (3.57e-3)" "unprognostic (5.24e-2)" NAGS "AGAS, ARGA, NAT7" ENSG00000161653 "N-acetylglutamate synthase" Q8N159 17 44004622-44009068 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Urea cycle" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 14.9;liver: 49.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 9.8;Enterocytes: 43.2;Epididymal efferent duct absorptive cells: 15.9;Epididymal principal cells: 13.5;Esophageal apical cells: 15.7;Hepatocytes: 23.8;Late primary spermatocytes: 23.1" "Cell type enriched" "Detected in single" 7 "endothelial cell: 6.5" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 18.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Breast - Breast glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA027300 Approved Mitochondria "Intracellular and membrane" Enzyme NA NA "Cluster 77: Intestine - Digestion" "Cluster 24: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 1: Enterocytes - Absorption and Digestion" 5 Mitochondria "HPA027300: " "unprognostic (1.02e-2)" "potential prognostic favorable (4.60e-4)" "unprognostic (9.94e-2)" "unprognostic (2.29e-2)" "unprognostic (9.75e-3)" "unprognostic (3.91e-2)" "unprognostic (4.61e-2)" "potential prognostic unfavorable (5.23e-4)" "unprognostic (3.18e-3)" "unprognostic (5.92e-2)" "unprognostic (1.20e-1)" "unprognostic (1.70e-1)" "potential prognostic favorable (6.19e-4)" "unprognostic (7.34e-2)" "unprognostic (2.48e-1)" "potential prognostic favorable (6.90e-4)" "unprognostic (2.43e-1)" "unprognostic (6.09e-3)" "unprognostic (2.73e-3)" "potential prognostic unfavorable (5.35e-5)" "unprognostic (1.95e-2)" "unprognostic (1.49e-2)" "unprognostic (1.53e-1)" "unprognostic (1.81e-1)" "unprognostic (2.03e-1)" "unprognostic (1.73e-1)" "unprognostic (4.05e-1)" NAIF1 "bA379C10.2, C9orf90, DKFZp762G199" ENSG00000171169 "Nuclear apoptosis inducing factor 1" Q69YI7 9 128061233-128068206 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 20.3;Late primary spermatocytes: 21.1;Late spermatids: 18.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054898, HPA064931" Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 4 Nucleoplasm "Plasma membrane, Cytosol" "HPA054898: , HPA064931: " "unprognostic (6.53e-3)" "unprognostic (2.43e-2)" "unprognostic (3.36e-3)" "unprognostic (1.59e-1)" "unprognostic (1.58e-2)" "unprognostic (2.38e-1)" "unprognostic (2.34e-1)" "unprognostic (1.66e-3)" "unprognostic (2.04e-1)" "unprognostic (4.72e-1)" "potential prognostic favorable (3.70e-4)" "unprognostic (2.32e-2)" "unprognostic (6.12e-2)" "unprognostic (3.30e-3)" "unprognostic (1.73e-2)" "unprognostic (2.26e-1)" "unprognostic (2.11e-2)" "unprognostic (2.43e-2)" "unprognostic (1.75e-2)" "unprognostic (9.36e-2)" "unprognostic (3.79e-2)" "unprognostic (1.21e-2)" "unprognostic (8.70e-3)" "unprognostic (9.98e-2)" "unprognostic (9.81e-2)" "unprognostic (9.96e-2)" "unprognostic (1.57e-1)" "unprognostic (1.62e-1)" "unprognostic (2.37e-1)" "unprognostic (1.22e-1)" "unprognostic (1.14e-1)" NAIP "BIRC1, NLRB1" ENSG00000249437 "NLR family apoptosis inhibitory protein" Q13075 5 70968166-71025339 "Cancer-related genes, Essential proteins, Predicted intracellular proteins" "Apoptosis, Immunity, Inflammatory response, Innate immunity" "Protease inhibitor, Thiol protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 31.0" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 167.2;Loop of henle epithelial cells: 133.1;Microglia: 28.0;Papillary tip epithelial cells: 69.7;Podocytes: 99.1;Proximal tubule cells: 79.6;Renal collecting duct intercalated cells: 96.9;Renal collecting duct principal cells: 66.0;Renal connecting tubule cells: 108.7" "Cell type enriched" "Detected in all" 5 "central nervous system macrophage: 35.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 8.3;myeloid DC: 5.2" "Group enriched" "Detected in many" 16 "dendritic cells: 5.2;granulocytes: 4.5;monocytes: 8.3" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Macrophages, Adrenal gland - Macrophages, Lung - Neutrophils_2, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" HPA042438 Approved NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 5: Spleen - Immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 105: Non-specific - Mixed function" 1 "HPA042438: " "unprognostic (2.92e-1)" "unprognostic (6.55e-2)" "unprognostic (8.12e-2)" "unprognostic (9.83e-3)" "unprognostic (2.76e-2)" "unprognostic (1.88e-2)" "unprognostic (2.20e-1)" "unprognostic (1.17e-2)" "unprognostic (7.84e-2)" "unprognostic (1.42e-1)" "unprognostic (3.88e-3)" "unprognostic (2.15e-2)" "unprognostic (1.80e-2)" NALCN "bA430M15.1, CanIon, VGCNL1" ENSG00000102452 "Sodium leak channel, non-selective" Q8IZF0 13 101053776-101416508 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 15.1" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 255.3;Astrocytes: 233.4;Bergmann glia: 241.6;Brain excitatory neurons: 331.6;Brain inhibitory neurons: 382.8;Corticotrophs: 326.5;Gonadotrophs: 418.8;Lactotrophs: 453.9;Oligodendrocyte progenitor cells: 440.0;Oligodendrocytes: 606.0;Other brain neurons: 340.3;Pituicytes/FSCs: 377.7;Retinal pigment epithelial cells: 366.6;Somatotrophs: 459.7;Thyrotrophs: 454.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "basophil: 2.5" "Lineage enriched" "Detected in single" 7 "granulocytes: 2.5" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Liver - Hepatic stellate cells, Skin - Eccrine sweat gland cells, Spleen - Smooth muscle cells, Stomach - Gastric enteroendocrine cells, Testis - Peritubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031889, HPA031890, HPA031958" Approved Uncertain "Nucleoli,Plasma membrane,Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Cytosol" Yes NA "Cluster 32: Basophils - Transcription" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 34: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 1 "Microtubules, Primary cilium, Cytosol" "Nucleoli, Plasma membrane, Cytokinetic bridge, Mitotic spindle" "HPA031889: , HPA031890: , HPA031958: " "unprognostic (1.20e-1)" "unprognostic (1.37e-1)" "unprognostic (7.49e-3)" "unprognostic (4.22e-2)" "unprognostic (3.31e-3)" "unprognostic (5.87e-2)" "unprognostic (8.02e-2)" "unprognostic (3.71e-1)" "unprognostic (3.67e-2)" "unprognostic (3.12e-1)" "unprognostic (1.07e-1)" "unprognostic (1.94e-3)" "unprognostic (2.19e-2)" "potential prognostic unfavorable (5.39e-5)" "unprognostic (3.75e-2)" "unprognostic (2.00e-2)" "unprognostic (1.27e-1)" NALF1 "FAM155A, NLF-1" ENSG00000204442 "NALCN channel auxiliary factor 1" B1AL88 13 107163510-107867496 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.5;pituitary gland: 4.8" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 1765.7;Brain excitatory neurons: 3413.0;Brain inhibitory neurons: 2366.4;Corticotrophs: 7761.0;Endometrial stromal cells: 1952.4;Gonadotrophs: 3615.8;Lactotrophs: 6906.1;Oligodendrocyte progenitor cells: 2806.7;Other brain neurons: 3017.0;Pituicytes/FSCs: 1857.7;Retinal amacrine cells: 2226.0;Retinal ganglion cells: 2387.2;Retinal horizontal cells: 1831.1;Somatotrophs: 6511.6;Thyrotrophs: 6008.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 7.4" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039453 Enhanced NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" "HPA039453: " "unprognostic (2.74e-1)" "unprognostic (1.90e-1)" "potential prognostic favorable (1.91e-4)" "unprognostic (4.13e-2)" "unprognostic (2.72e-2)" "unprognostic (1.37e-1)" NALF2 "CXorf63, FAM155B, TED, TMEM28" ENSG00000130054 "NALCN channel auxiliary factor 2" O75949 X 69504326-69532508 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "heart muscle: 34.6" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 14.4;Differentiating spermatogonia: 4.2;Endometrial glandular cells: 4.0;Endometrial luminal cells: 7.9;Hepatic stellate cells: 6.5;Neuroendocrine cells: 6.2;Oligodendrocyte progenitor cells: 4.2;Parietal cells: 5.3;Retinal amacrine cells: 4.1;Tuft cells: 11.5" "Cell type enhanced" "Detected in many" "midbrain-derived inhibitory: 11.4" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 11.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Corticotropes, Prostate - Prostate glandular cells, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036093 Uncertain NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" "HPA036093: " "unprognostic (1.40e-3)" "potential prognostic unfavorable (1.76e-5)" "unprognostic (1.85e-1)" "unprognostic (2.23e-1)" "unprognostic (2.40e-1)" "unprognostic (1.81e-3)" "unprognostic (7.94e-2)" "potential prognostic unfavorable (8.69e-4)" "unprognostic (2.59e-2)" "unprognostic (7.55e-2)" "unprognostic (2.13e-1)" "unprognostic (1.67e-2)" "unprognostic (2.58e-1)" "unprognostic (3.46e-2)" "unprognostic (1.42e-2)" "unprognostic (6.95e-2)" "unprognostic (2.64e-1)" "unprognostic (6.68e-2)" NAMPT "PBEF, PBEF1" ENSG00000105835 "Nicotinamide phosphoribosyltransferase" P43490 7 106248298-106285966 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Biological rhythms, Pyridine nucleotide biosynthesis" "Cytokine, Glycosyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 339.4" "Cell type enriched" "Detected in many" 8 "Neutrophils: 41123.4" "Group enriched" "Detected in all" 4 "endothelial cell: 662.1;leukocyte: 356.8;vascular associated smooth muscle cell: 237.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 7 "neutrophil: 281.8" "Lineage enriched" "Detected in all" 9 "granulocytes: 281.8" "Low cancer specificity" "Detected in all" "Colon - Neutrophils, Liver - Neutrophils, Spleen - Neutrophils_2, Thyroid gland - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034349, HPA047776, HPA057722" Approved Approved "Nuclear speckles,Cell Junctions" "Secreted to blood" Cytokine NA NA 2140000 1600000 "Cluster 35: Neutrophils - Protein binding" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 15 "Nuclear speckles" "Cell Junctions" "CAB034349: , HPA047776: , HPA057722: " "unprognostic (1.54e-1)" "unprognostic (3.80e-2)" "unprognostic (2.53e-1)" "unprognostic (2.81e-2)" "unprognostic (1.45e-2)" "unprognostic (1.62e-1)" "unprognostic (3.45e-2)" "unprognostic (2.18e-3)" "unprognostic (2.31e-3)" "unprognostic (1.04e-2)" "unprognostic (3.38e-3)" "potential prognostic unfavorable (8.70e-4)" "unprognostic (3.46e-2)" "unprognostic (2.39e-1)" "unprognostic (1.16e-1)" "unprognostic (2.29e-2)" "unprognostic (7.70e-3)" "unprognostic (3.99e-2)" "unprognostic (1.30e-1)" "unprognostic (3.07e-3)" "unprognostic (1.90e-1)" "unprognostic (2.36e-3)" "potential prognostic unfavorable (4.04e-5)" "unprognostic (2.55e-1)" "unprognostic (6.58e-2)" "unprognostic (1.81e-1)" "unprognostic (2.59e-1)" "unprognostic (1.03e-1)" "unprognostic (1.92e-1)" "unprognostic (8.37e-2)" "unprognostic (3.51e-2)" NANOG "FLJ12581, FLJ40451" ENSG00000111704 "Nanog homeobox" Q9H9S0 12 7787794-7799146 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 2.1;Distal convoluted tubule cells: 3.3;Foveolar cells: 2.7;Loop of henle epithelial cells: 2.1;Papillary tip epithelial cells: 1.5;Parietal cells: 1.8;Podocytes: 1.8;Proximal tubule cells: 2.0;Renal collecting duct intercalated cells: 2.2;Renal collecting duct principal cells: 1.5;Renal connecting tubule cells: 2.3" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 238 "Testicular Germ Cell Tumor (TCGA): 293.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 1.7" "Group enriched" "Detected in many" 5 "dendritic cells: 1.7;granulocytes: 1.4" "Cancer enriched" "Detected in single" 81 "testis cancer: 23.7" "Low region specificity" "Detected in all" "CAB019380, HPA072117, CAB080504, CAB080505" Supported Enhanced Nucleoplasm NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 15: Non-specific - Transcription" "Cluster 34: Testis cancer - Unknown function" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 10 Nucleoplasm "CAB019380: , CAB080504: , CAB080505: , HPA072117: " "unprognostic (6.34e-2)" "unprognostic (4.36e-2)" "unprognostic (5.15e-2)" "unprognostic (1.76e-1)" "unprognostic (1.40e-1)" NANOGNB ENSG00000205857 "NANOG neighbor homeobox" Q7Z5D8 12 7765216-7774121 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Undifferentiated spermatogonia: 1.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Testicular Germ Cell Tumor (TCGA): 2.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA060371 Uncertain NA NA "Cluster 48: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 46: Skeletal myocytes - Muscle structure & formation" "HPA060371: " "unprognostic (1.02e-1)" NANOGP8 ENSG00000255192 "Nanog homeobox retrogene P8" Q6NSW7 15 35083410-35085295 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Adrenal cortex cells: 3.1;Early spermatids: 1.2;Sertoli cells: 3.4" "Cancer enriched" "Detected in some" 61 "Testicular Germ Cell Tumor (TCGA): 87.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 16 "testis cancer: 10.7" HPA072117 Supported Nucleoplasm,Vesicles NA NA "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 34: Testis cancer - Unknown function" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" Nucleoplasm Vesicles "HPA072117: " "unprognostic (1.37e-1)" "unprognostic (6.84e-2)" NANOS1 "NOS1, ZC2HC12A" ENSG00000188613 "Nanos C2HC-type zinc finger 1" Q8WY41 10 119029714-119033730 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Translation regulation" "Repressor, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 36.2" "Cell type enhanced" "Detected in many" "Breast lactating cells: 18.4;Breast secretory cells: 10.6;Cone photoreceptor cells: 10.4;Epididymal efferent duct ciliated cells: 12.6;Müller glia: 10.2;Pancreatic islet cells: 18.3;Retinal pigment epithelial cells: 21.3" "Cell type enhanced" "Detected in many" "Bergmann glia: 12.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Bile duct cancer: 26.5" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Minor Salivary Gland - Minor salivary glandular cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" CAB012219 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 3 "Nucleoplasm, Cytosol" "CAB012219: " "unprognostic (4.06e-2)" "potential prognostic unfavorable (8.36e-6)" "unprognostic (2.76e-2)" "unprognostic (2.35e-1)" "unprognostic (1.90e-2)" "unprognostic (2.47e-2)" "unprognostic (2.63e-1)" "unprognostic (3.11e-2)" "unprognostic (4.26e-1)" "unprognostic (3.32e-2)" "unprognostic (2.60e-2)" "unprognostic (4.62e-2)" "unprognostic (9.52e-3)" "unprognostic (3.68e-1)" "unprognostic (3.33e-1)" "unprognostic (1.21e-1)" "unprognostic (1.57e-1)" "unprognostic (2.70e-2)" "unprognostic (2.43e-2)" "unprognostic (1.18e-1)" "unprognostic (1.27e-1)" "unprognostic (2.16e-1)" "unprognostic (1.74e-1)" "unprognostic (2.26e-2)" "unprognostic (2.30e-1)" "unprognostic (5.47e-2)" NANOS2 "NOS2, ZC2HC12B" ENSG00000188425 "Nanos C2HC-type zinc finger 2" P60321 19 45913214-45914778 "Predicted intracellular proteins" "Differentiation, Spermatogenesis, Translation regulation" "Developmental protein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 24 "testis: 3.6" "Cell type enriched" "Detected in some" 13 "Undifferentiated spermatogonia: 19.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" HPA014190 Approved NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 5 "HPA014190: " NANOS3 "NANOS1L, NOS3, ZC2HC12C" ENSG00000187556 "Nanos C2HC-type zinc finger 3" P60323 19 13862063-13880757 "Predicted intracellular proteins" "Differentiation, Oogenesis, Spermatogenesis, Translation regulation" "Developmental protein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 2.7;testis: 3.5" "Group enriched" "Detected in some" 4 "Brain excitatory neurons: 8.2;Brain inhibitory neurons: 7.3;Differentiating spermatogonia: 8.2;Oligodendrocyte progenitor cells: 5.3;Other brain neurons: 9.4;Undifferentiated spermatogonia: 17.4" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in some" 89 "Testicular Germ Cell Tumor (TCGA): 126.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Neuroblastoma: 1.3" "Testis - Spermatogonia" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA062989, CAB080164" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 67: Testis - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 98: Neurons - Neurotransmission & signaling" 1 Nucleoplasm Cytosol "CAB080164: , HPA062989: " "unprognostic (3.10e-1)" "unprognostic (1.23e-1)" "unprognostic (2.68e-3)" "unprognostic (2.98e-1)" "unprognostic (1.30e-2)" "unprognostic (3.86e-2)" "unprognostic (2.04e-1)" NANP "C20orf147, dJ694B14.3, HDHD4, MGC26833" ENSG00000170191 "N-acetylneuraminic acid phosphatase" Q8TBE9 20 25612935-25624014 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 21.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050342 Uncertain Approved "Nuclear membrane,Cytosol" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 62: Non-specific - Plasma proteins" "Cluster 17: Non-specific - RNA processing" 1 Cytosol "Nuclear membrane" "HPA050342: " "unprognostic (6.36e-2)" "unprognostic (1.75e-1)" "unprognostic (1.48e-1)" "unprognostic (1.86e-1)" "unprognostic (2.50e-2)" "unprognostic (6.93e-2)" "unprognostic (3.06e-1)" "unprognostic (6.24e-3)" "unprognostic (4.51e-1)" "unprognostic (3.13e-2)" "unprognostic (9.74e-3)" "unprognostic (2.77e-1)" "unprognostic (3.72e-2)" "potential prognostic unfavorable (1.96e-5)" "unprognostic (3.47e-3)" "unprognostic (1.72e-1)" "unprognostic (2.27e-2)" "unprognostic (1.72e-1)" "unprognostic (1.81e-3)" "unprognostic (1.68e-2)" "unprognostic (2.66e-1)" "unprognostic (2.04e-1)" "unprognostic (3.47e-3)" "unprognostic (2.71e-1)" "unprognostic (3.25e-2)" "unprognostic (2.02e-2)" "unprognostic (8.90e-2)" "unprognostic (3.42e-1)" "unprognostic (2.79e-1)" "unprognostic (1.34e-3)" "unprognostic (2.54e-1)" NANS SAS ENSG00000095380 "N-acetylneuraminate synthase" Q9NR45 9 98056732-98083077 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 289.2;Goblet cells: 310.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019223 Approved Enhanced Nucleoplasm No No 290000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 60: Stomach - Digestion" "Cluster 21: Non-specific - Metabolism" "Cluster 27: Breast cancer - Unknown function" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 9 Nucleoplasm "HPA019223: " "unprognostic (7.60e-3)" "unprognostic (3.73e-2)" "unprognostic (4.49e-1)" "unprognostic (7.82e-2)" "unprognostic (1.57e-1)" "unprognostic (4.36e-1)" "unprognostic (2.75e-3)" "unprognostic (2.20e-1)" "unprognostic (3.01e-2)" "unprognostic (1.30e-3)" "unprognostic (8.55e-3)" "unprognostic (2.40e-1)" "unprognostic (1.11e-1)" "validated prognostic unfavorable (4.01e-6)" "validated prognostic unfavorable (8.34e-6)" "unprognostic (1.44e-3)" "unprognostic (2.62e-1)" "unprognostic (2.91e-1)" "unprognostic (2.01e-1)" "unprognostic (6.62e-2)" "unprognostic (1.51e-1)" "unprognostic (1.05e-2)" "unprognostic (2.81e-2)" "unprognostic (1.51e-1)" "unprognostic (2.33e-2)" "potential prognostic unfavorable (4.26e-4)" "unprognostic (2.60e-2)" "unprognostic (4.74e-2)" "unprognostic (3.23e-2)" "unprognostic (1.85e-1)" "unprognostic (1.65e-3)" NAP1L1 "MGC23410, MGC8688, NAP1, NAP1L, NRP" ENSG00000187109 "Nucleosome assembly protein 1 like 1" P55209 12 76036585-76084735 "Plasma proteins, Predicted intracellular proteins" Neurogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Platelets: 4031.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028861 Approved Uncertain Microtubules NA NA 13000000 "Cluster 33: Non-specific - ATP binding" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 47: Platelets - Hemostasis" 104 Microtubules "HPA028861: " "unprognostic (6.00e-3)" "unprognostic (1.81e-2)" "unprognostic (1.51e-2)" "unprognostic (1.06e-2)" "unprognostic (6.61e-2)" "unprognostic (1.05e-2)" "unprognostic (1.11e-2)" "unprognostic (1.15e-1)" "unprognostic (4.55e-2)" "unprognostic (2.64e-2)" "unprognostic (1.31e-2)" "unprognostic (8.73e-3)" "unprognostic (4.11e-3)" "validated prognostic unfavorable (1.20e-8)" "validated prognostic unfavorable (7.36e-6)" "unprognostic (7.10e-2)" "unprognostic (1.71e-3)" "unprognostic (1.84e-1)" "unprognostic (1.66e-1)" "unprognostic (4.43e-2)" "unprognostic (1.34e-2)" "unprognostic (6.24e-2)" "unprognostic (1.79e-1)" "unprognostic (1.36e-1)" "unprognostic (6.86e-2)" "unprognostic (2.05e-2)" "unprognostic (1.06e-1)" "unprognostic (3.45e-2)" "unprognostic (1.59e-1)" "unprognostic (6.91e-2)" "unprognostic (2.08e-3)" NAP1L2 "BPX, MGC26243" ENSG00000186462 "Nucleosome assembly protein 1 like 2" Q9ULW6 X 73212299-73214851 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 76.3" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 36.6;Brain inhibitory neurons: 33.5;Corticotrophs: 20.4;Lactotrophs: 17.4;Medullary thymic epithelial cells: 16.8;Other brain neurons: 35.5;Prostatic glandular cells: 29.8;Retinal amacrine cells: 27.3;Somatotrophs: 21.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 11.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Myeloma: 9.2" "Adipose subcutaneous - Smooth muscle cells, Skeletal muscle - Fibroblasts, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054050, HPA057065" Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 27: Cerebellum - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 98: Neurons - Neurotransmission & signaling" 13 "Plasma membrane, Cytosol" "HPA054050: , HPA057065: " "unprognostic (3.10e-1)" "unprognostic (3.76e-2)" "unprognostic (1.00e-1)" "unprognostic (2.26e-1)" "unprognostic (1.79e-1)" "unprognostic (2.77e-3)" "unprognostic (9.70e-2)" "unprognostic (4.20e-2)" "unprognostic (2.29e-1)" "unprognostic (1.32e-2)" "unprognostic (8.61e-2)" "unprognostic (9.03e-3)" "unprognostic (2.56e-2)" "unprognostic (1.12e-2)" "unprognostic (5.53e-2)" "unprognostic (2.40e-2)" "potential prognostic favorable (2.99e-4)" "unprognostic (2.29e-2)" "unprognostic (3.72e-2)" "unprognostic (4.18e-1)" "unprognostic (1.76e-1)" NAP1L3 "MB20, MGC26312, NPL3" ENSG00000186310 "Nucleosome assembly protein 1 like 3" Q99457 X 93670930-93673578 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 119.5" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 46.5;Brain inhibitory neurons: 63.7;Corticotrophs: 29.9;Megakaryocytes: 24.7;Oligodendrocyte progenitor cells: 21.2;Other brain neurons: 84.0;Pituicytes/FSCs: 21.3;Retinal amacrine cells: 40.7;Retinal bipolar cells: 23.5;Retinal horizontal cells: 38.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 20.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 4.1" "Group enriched" "Detected in many" 25 "NK-cells: 3.1;T-cells: 4.1" "Cancer enhanced" "Detected in many" "testis cancer: 19.1" "Colon - Colon enteroendocrine cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026075 Uncertain Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 27: Cerebellum - Synaptic function" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 98: Neurons - Neurotransmission & signaling" 5 Vesicles "Nucleoplasm, Nucleoli" "HPA026075: " "unprognostic (7.04e-3)" "unprognostic (1.58e-1)" "unprognostic (2.52e-2)" "unprognostic (6.78e-2)" "unprognostic (2.70e-1)" "potential prognostic favorable (1.30e-4)" "unprognostic (2.70e-1)" "unprognostic (1.62e-1)" "unprognostic (2.39e-1)" "unprognostic (1.39e-2)" "unprognostic (2.53e-1)" "unprognostic (8.05e-2)" "unprognostic (1.23e-1)" "unprognostic (2.68e-2)" "unprognostic (2.76e-3)" "unprognostic (1.91e-1)" "unprognostic (9.38e-2)" "unprognostic (4.38e-2)" "unprognostic (1.63e-1)" "unprognostic (7.72e-2)" "unprognostic (8.20e-2)" "unprognostic (5.50e-2)" NAP1L4 NAP2 ENSG00000205531 "Nucleosome assembly protein 1 like 4" Q99733 11 2944431-2992377 "Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 378.9;Distal convoluted tubule cells: 239.4;Renal collecting duct intercalated cells: 213.8;Renal connecting tubule cells: 188.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB011567 Approved Supported Nucleoplasm NA NA 3800000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 102: Non-specific - Mixed function" 32 Nucleoplasm "CAB011567: " "unprognostic (8.46e-2)" "unprognostic (9.64e-2)" "unprognostic (4.00e-2)" "unprognostic (6.58e-3)" "unprognostic (7.12e-2)" "unprognostic (6.43e-2)" "potential prognostic unfavorable (8.13e-4)" "unprognostic (1.10e-1)" "unprognostic (6.76e-2)" "unprognostic (9.51e-2)" "unprognostic (2.87e-2)" "unprognostic (5.30e-2)" "unprognostic (2.33e-2)" "unprognostic (2.69e-3)" "potential prognostic unfavorable (5.65e-4)" "unprognostic (7.75e-2)" "unprognostic (5.89e-3)" "unprognostic (1.34e-1)" "unprognostic (2.26e-2)" "unprognostic (6.29e-2)" "unprognostic (1.42e-1)" "unprognostic (2.17e-1)" "unprognostic (1.37e-3)" "unprognostic (7.45e-2)" "unprognostic (7.01e-2)" "unprognostic (2.85e-2)" "unprognostic (3.31e-2)" "unprognostic (1.45e-1)" "unprognostic (1.79e-1)" "potential prognostic unfavorable (9.46e-5)" "unprognostic (2.53e-3)" NAP1L5 DRLM ENSG00000177432 "Nucleosome assembly protein 1 like 5" Q96NT1 4 88695913-88697829 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "brain: 127.0" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 31.9;Brain excitatory neurons: 31.7;Brain inhibitory neurons: 36.1;Corticotrophs: 28.8;Decidual stromal cells: 28.7;Other brain neurons: 72.2;Smooth muscle cells: 31.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 24.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Neuroblastoma: 20.3" "Colon - Colon enteroendocrine cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" HPA058227 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 98: Neurons - Neurotransmission & signaling" 9 Nucleoplasm Cytosol "HPA058227: " "unprognostic (2.11e-3)" "unprognostic (8.13e-2)" "unprognostic (5.97e-3)" "unprognostic (7.48e-2)" "unprognostic (1.76e-1)" "unprognostic (1.54e-1)" "unprognostic (2.00e-1)" "unprognostic (1.18e-2)" "unprognostic (3.25e-2)" "unprognostic (1.23e-2)" "potential prognostic favorable (9.32e-5)" "unprognostic (6.58e-3)" "unprognostic (6.11e-2)" "unprognostic (3.78e-2)" "unprognostic (3.05e-2)" "unprognostic (2.43e-2)" "unprognostic (5.60e-2)" "unprognostic (2.32e-1)" "unprognostic (1.42e-1)" "unprognostic (2.71e-1)" "unprognostic (1.72e-1)" "potential prognostic favorable (3.74e-4)" "unprognostic (9.69e-2)" "unprognostic (1.57e-1)" "unprognostic (8.80e-2)" "unprognostic (6.97e-2)" "unprognostic (2.27e-1)" "unprognostic (3.32e-3)" "unprognostic (1.93e-1)" "unprognostic (1.13e-1)" "unprognostic (2.23e-1)" NAPA ENSG00000105402 "NSF attachment protein alpha" P54920 19 47487637-47515091 "Essential proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 180.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010100, HPA046149, HPA050196" Approved Uncertain Cytosol NA NA 1500000 "Cluster 29: Non-specific - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 4: Non-specific - Transcription" "Cluster 65: Non-specific - Cell growth & division" 159 Cytosol "CAB010100: , HPA046149: , HPA050196: " "unprognostic (6.54e-2)" "unprognostic (7.45e-2)" "unprognostic (7.47e-2)" "unprognostic (4.19e-3)" "unprognostic (4.69e-1)" "unprognostic (5.85e-2)" "unprognostic (2.32e-2)" "unprognostic (1.04e-1)" "unprognostic (2.49e-2)" "unprognostic (2.62e-1)" "potential prognostic favorable (3.61e-6)" "unprognostic (6.03e-2)" "potential prognostic favorable (1.85e-4)" "unprognostic (8.97e-2)" "potential prognostic favorable (9.92e-4)" "unprognostic (1.87e-1)" "unprognostic (1.32e-1)" "unprognostic (2.17e-2)" "unprognostic (5.52e-2)" "unprognostic (2.64e-2)" "unprognostic (3.46e-1)" "unprognostic (2.49e-2)" "unprognostic (2.11e-2)" "unprognostic (1.07e-2)" "unprognostic (1.85e-1)" "unprognostic (7.63e-2)" "unprognostic (4.39e-2)" "unprognostic (4.20e-2)" "unprognostic (5.14e-2)" "unprognostic (1.19e-1)" "unprognostic (4.00e-1)" NAPB "SNAP-BETA, SNAPB" ENSG00000125814 "NSF attachment protein beta" Q9H115 20 23374519-23421519 "Human disease related genes, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "brain: 190.1;retina: 142.7" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 167.9;Retinal bipolar cells: 166.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037225, CAB037227, HPA046149, HPA050196" Supported Uncertain Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 24: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 39 Cytosol "CAB037225: , CAB037227: , HPA046149: , HPA050196: " "unprognostic (5.56e-3)" "unprognostic (1.15e-1)" "unprognostic (4.91e-2)" "unprognostic (8.52e-2)" "unprognostic (7.31e-2)" "unprognostic (2.44e-2)" "unprognostic (5.69e-2)" "unprognostic (5.77e-2)" "unprognostic (9.52e-2)" "unprognostic (2.31e-2)" "unprognostic (5.65e-2)" "unprognostic (2.70e-1)" "unprognostic (8.84e-2)" "potential prognostic unfavorable (5.45e-4)" "unprognostic (2.06e-1)" "unprognostic (1.14e-2)" "unprognostic (1.70e-1)" "unprognostic (5.72e-2)" "unprognostic (1.09e-1)" "unprognostic (3.20e-1)" "unprognostic (3.19e-1)" "unprognostic (1.48e-3)" "unprognostic (2.34e-2)" "unprognostic (7.26e-3)" "unprognostic (2.12e-1)" "unprognostic (7.67e-2)" "unprognostic (6.22e-2)" "unprognostic (1.03e-1)" "unprognostic (1.32e-1)" "unprognostic (2.09e-2)" "unprognostic (2.33e-1)" NAPEPLD "C7orf18, FMP30, NAPE-PLD" ENSG00000161048 "N-acyl phosphatidylethanolamine phospholipase D" Q6IQ20 7 103099776-103149560 "Enzymes, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism, Phospholipid degradation, Phospholipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 72.1;Bergmann glia: 90.6;Brain excitatory neurons: 84.2;Brain inhibitory neurons: 63.0;Cardiomyocytes: 87.9;Distal convoluted tubule cells: 68.7;Early spermatids: 111.2;Loop of henle epithelial cells: 145.9;Oligodendrocyte progenitor cells: 186.8;Oligodendrocytes: 263.3;Papillary tip epithelial cells: 60.4;Podocytes: 258.6;Proximal tubule cells: 91.0;Renal collecting duct intercalated cells: 62.1;Renal collecting duct principal cells: 130.8;Renal connecting tubule cells: 63.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019832, HPA024338" Approved Uncertain Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 34: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" Cytosol "HPA019832: , HPA024338: " "unprognostic (1.14e-2)" "unprognostic (6.44e-2)" "unprognostic (5.44e-2)" "unprognostic (2.82e-2)" "unprognostic (6.10e-2)" "unprognostic (1.21e-1)" "unprognostic (6.76e-2)" "unprognostic (7.25e-2)" "unprognostic (5.54e-2)" "unprognostic (7.08e-2)" "potential prognostic favorable (3.35e-8)" "unprognostic (3.00e-2)" "unprognostic (2.26e-2)" "unprognostic (6.71e-2)" "unprognostic (8.94e-3)" "unprognostic (5.24e-2)" "unprognostic (5.54e-2)" "unprognostic (3.06e-1)" "unprognostic (1.82e-1)" "unprognostic (6.97e-2)" "unprognostic (1.61e-1)" "potential prognostic unfavorable (7.56e-5)" "unprognostic (8.26e-2)" "unprognostic (1.82e-1)" "potential prognostic favorable (9.54e-4)" "unprognostic (1.46e-2)" "unprognostic (9.80e-3)" "unprognostic (1.55e-1)" "unprognostic (4.73e-1)" "unprognostic (2.51e-2)" "unprognostic (1.67e-1)" NAPG ENSG00000134265 "NSF attachment protein gamma" Q99747 18 10525905-10552764 "Essential proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008208, HPA011389" Enhanced Supported "Plasma membrane" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 27: Cerebellum - Synaptic function" "Cluster 49: Hindbrain - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 35: Neurons - Synaptic function & neurogenesis" 44 "Plasma membrane" "HPA008208: , HPA011389: " "unprognostic (2.19e-3)" "unprognostic (3.74e-2)" "unprognostic (2.01e-1)" "unprognostic (3.64e-2)" "unprognostic (4.02e-3)" "unprognostic (1.29e-2)" "unprognostic (3.04e-1)" "unprognostic (2.13e-3)" "unprognostic (2.22e-2)" "unprognostic (2.83e-1)" "potential prognostic favorable (3.55e-8)" "unprognostic (6.95e-2)" "unprognostic (2.48e-1)" "unprognostic (1.73e-1)" "unprognostic (9.32e-3)" "unprognostic (2.89e-1)" "potential prognostic favorable (8.49e-4)" "unprognostic (1.33e-1)" "unprognostic (7.99e-2)" "unprognostic (5.76e-2)" "unprognostic (1.34e-1)" "unprognostic (2.54e-3)" "unprognostic (1.49e-3)" "unprognostic (6.83e-2)" "unprognostic (1.72e-2)" "unprognostic (3.73e-3)" "unprognostic (6.46e-2)" "unprognostic (1.10e-1)" "unprognostic (7.60e-2)" "unprognostic (2.15e-1)" "unprognostic (1.89e-1)" NAPRT "NAPRT1, PP3856" ENSG00000147813 "Nicotinate phosphoribosyltransferase" Q6XQN6 8 143574785-143578649 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Ligase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 103.0" "Cell type enhanced" "Detected in many" "Colonocytes: 246.9;Enteric transient amplifying cells: 152.2;Enterocytes: 505.0;Esophageal apical cells: 900.8;Esophageal suprabasal cells: 158.6;Foveolar cells: 154.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023739, HPA024017, CAB068206, CAB068207" Enhanced Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 2400000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 40: Non-specific - Unknown function" "Cluster 84: Apical squamous epithelium - Cornification" 2 "Golgi apparatus" "Nucleoplasm, Cytosol" "CAB068206: , CAB068207: , HPA023739: , HPA024017: " "unprognostic (2.88e-1)" "unprognostic (3.78e-2)" "unprognostic (5.35e-2)" "unprognostic (2.59e-1)" "unprognostic (1.34e-1)" "unprognostic (1.55e-1)" "unprognostic (1.30e-1)" "unprognostic (1.60e-1)" "unprognostic (6.73e-3)" "potential prognostic favorable (8.67e-6)" "unprognostic (1.66e-1)" "potential prognostic favorable (8.12e-4)" "unprognostic (1.19e-1)" "unprognostic (2.05e-1)" "unprognostic (6.91e-2)" "unprognostic (1.11e-1)" "unprognostic (2.68e-2)" "unprognostic (1.62e-1)" "unprognostic (5.98e-2)" "unprognostic (4.79e-2)" "potential prognostic unfavorable (4.62e-4)" "unprognostic (2.29e-1)" "unprognostic (4.12e-2)" "unprognostic (1.67e-1)" "unprognostic (9.98e-2)" "unprognostic (3.11e-2)" "unprognostic (3.02e-1)" "unprognostic (2.96e-2)" "unprognostic (3.49e-1)" NAPSA "KAP, Kdap, NAP1, NAPA" ENSG00000131400 "Napsin A aspartic peptidase" O96009 19 50358472-50365830 "Enzymes, Plasma proteins, Predicted secreted proteins" "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "lung: 983.7" "Group enriched" "Detected in many" 7 "Alveolar cells type 1: 1828.9;Alveolar cells type 2: 5089.1;Transitional alveolar cells: 1533.5" "Low cell type specificity" "Detected in some" "Cancer enriched" "Detected in many" 11 "Lung Adenocarcinoma (TCGA): 1859.5" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "memory B-cell: 2.8;plasmacytoid DC: 4.9" "Group enriched" "Detected in many" 9 "B-cells: 2.8;dendritic cells: 4.9" "Cancer enhanced" "Detected in some" "lung cancer: 13.4;lymphoma: 19.4;ovarian cancer: 32.3" "Kidney - Proximal tubular cells, Lung - Alveolar cells type 2, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB009591, HPA045280, HPA047236, HPA047744" Enhanced "Secreted in other tissues" Enzyme NA NA 45000 "Cluster 13: Non-specific - Mitochondria" "Cluster 13: Lung - Secretion" "Cluster 15: Kidney cancer - Membrane components" "Cluster 81: Alveolar cells - Lung function" 4 "CAB009591: , HPA045280: , HPA047236: , HPA047744: " "unprognostic (7.46e-2)" "unprognostic (3.01e-2)" "unprognostic (3.98e-2)" "validated prognostic favorable (8.07e-7)" "validated prognostic favorable (1.57e-4)" "unprognostic (3.25e-2)" "unprognostic (2.82e-1)" "unprognostic (1.10e-3)" "unprognostic (1.15e-1)" "unprognostic (6.59e-3)" "unprognostic (5.91e-2)" "unprognostic (1.91e-1)" "unprognostic (1.46e-2)" "unprognostic (2.58e-2)" NARF "DKFZp434G0420, FLJ10067, IOP2" ENSG00000141562 "Nuclear prelamin A recognition factor" Q9UHQ1 17 82458180-82490537 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 781.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053006 Supported Nucleoplasm,Nucleoli NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 67: Testis - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 65: Non-specific - Cell growth & division" 3 Nucleoplasm Nucleoli "HPA053006: " "unprognostic (1.12e-2)" "unprognostic (1.87e-1)" "unprognostic (3.30e-1)" "unprognostic (3.97e-3)" "unprognostic (6.25e-2)" "unprognostic (7.95e-2)" "unprognostic (3.07e-2)" "unprognostic (4.09e-3)" "unprognostic (7.02e-2)" "unprognostic (1.25e-2)" "unprognostic (1.43e-1)" "unprognostic (3.86e-1)" "unprognostic (8.96e-3)" "potential prognostic unfavorable (5.60e-4)" "unprognostic (1.55e-3)" "unprognostic (9.97e-3)" "unprognostic (5.94e-2)" "unprognostic (3.02e-2)" "unprognostic (7.26e-3)" "unprognostic (1.55e-1)" "unprognostic (1.72e-1)" "potential prognostic favorable (1.40e-4)" "unprognostic (1.12e-2)" "unprognostic (9.47e-3)" "unprognostic (1.57e-3)" "unprognostic (2.48e-2)" "unprognostic (1.04e-1)" "unprognostic (2.37e-1)" "unprognostic (4.13e-2)" "potential prognostic unfavorable (5.10e-4)" "unprognostic (1.36e-1)" NARS1 NARS ENSG00000134440 "Asparaginyl-tRNA synthetase 1" O43776 18 57600656-57622213 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Epilepsy, Intellectual disability, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034257, HPA040017" Enhanced Supported Cytosol NA NA 57000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 76: Non-specific - Metabolism" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 13: Non-specific - Mixed function" "Cluster 97: Non-specific - Cellular respiration" 9 Cytosol "CAB034257: , HPA040017: " "unprognostic (1.74e-3)" "unprognostic (4.59e-2)" "unprognostic (1.04e-1)" "unprognostic (8.77e-3)" "unprognostic (1.97e-1)" "unprognostic (1.13e-1)" "unprognostic (4.20e-2)" "unprognostic (6.25e-2)" "unprognostic (3.50e-3)" "potential prognostic favorable (1.25e-5)" "unprognostic (7.05e-2)" "unprognostic (8.52e-3)" "potential prognostic unfavorable (9.02e-7)" "unprognostic (2.06e-2)" "unprognostic (4.74e-2)" "unprognostic (5.23e-2)" "unprognostic (2.77e-2)" "unprognostic (1.69e-1)" "unprognostic (7.22e-2)" "unprognostic (1.35e-1)" "unprognostic (1.11e-1)" "unprognostic (3.89e-2)" "unprognostic (5.25e-2)" "unprognostic (1.13e-2)" "unprognostic (1.35e-1)" "unprognostic (3.01e-2)" "unprognostic (2.44e-1)" "unprognostic (3.26e-1)" "unprognostic (1.28e-1)" NARS2 "DFNB94, FLJ23441, SLM5" ENSG00000137513 "Asparaginyl-tRNA synthetase 2, mitochondrial" Q96I59 11 78435620-78575194 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Deafness, Disease variant, Leigh syndrome, Non-syndromic deafness, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 342.6" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 289.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026793 Supported Supported Nucleoplasm,Mitochondria,Cytosol No No "Cluster 33: Non-specific - ATP binding" "Cluster 76: Non-specific - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 16 Mitochondria "Nucleoplasm, Cytosol" "HPA026793: " "unprognostic (2.41e-2)" "unprognostic (7.64e-2)" "unprognostic (1.80e-2)" "unprognostic (4.84e-2)" "unprognostic (9.68e-2)" "unprognostic (1.41e-2)" "unprognostic (6.85e-2)" "unprognostic (2.44e-3)" "unprognostic (4.01e-2)" "potential prognostic unfavorable (2.76e-4)" "potential prognostic favorable (6.47e-5)" "unprognostic (3.57e-1)" "unprognostic (8.17e-3)" "unprognostic (4.65e-2)" "unprognostic (2.48e-2)" "unprognostic (5.45e-2)" "unprognostic (4.02e-2)" "unprognostic (1.65e-1)" "unprognostic (4.95e-2)" "potential prognostic favorable (1.03e-4)" "unprognostic (2.15e-1)" "unprognostic (1.28e-1)" "unprognostic (3.08e-2)" "unprognostic (1.13e-1)" "unprognostic (3.90e-3)" "unprognostic (9.70e-2)" "potential prognostic unfavorable (2.23e-5)" "unprognostic (1.66e-1)" "unprognostic (5.51e-1)" "unprognostic (6.69e-2)" "unprognostic (4.40e-1)" NASP "DKFZp547F162, FLB7527, FLJ31599, FLJ35510, MGC19722, MGC20372, MGC2297, PRO1999" ENSG00000132780 "Nuclear autoantigenic sperm protein" P49321 1 45583846-45618904 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA replication, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Differentiating spermatogonia: 600.2;Early primary spermatocytes: 694.2;Erythrocyte progenitors: 484.5" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 386.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pancreas - Endothelial cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028136, HPA030518, HPA030520" Enhanced Enhanced Nucleoplasm NA Yes 320000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 6: Non-specific - Immune response" "Cluster 37: Non-specific - mRNA processing" "Cluster 20: Non-specific - Transcription regulation" 48 Nucleoplasm "HPA028136: , HPA030518: , HPA030520: " "unprognostic (6.05e-2)" "unprognostic (3.33e-2)" "unprognostic (1.05e-1)" "unprognostic (1.11e-1)" "unprognostic (8.76e-2)" "unprognostic (4.38e-1)" "unprognostic (2.09e-1)" "unprognostic (4.08e-2)" "unprognostic (9.42e-3)" "unprognostic (1.39e-2)" "unprognostic (2.19e-2)" "unprognostic (3.08e-1)" "unprognostic (7.80e-2)" "potential prognostic unfavorable (5.02e-7)" "unprognostic (8.61e-3)" "unprognostic (7.38e-3)" "unprognostic (1.02e-2)" "unprognostic (1.03e-2)" "unprognostic (9.49e-3)" "unprognostic (8.47e-2)" "unprognostic (2.23e-3)" "unprognostic (2.50e-1)" "unprognostic (2.36e-2)" "unprognostic (4.01e-2)" "unprognostic (1.25e-1)" "unprognostic (3.36e-2)" "unprognostic (2.69e-3)" "unprognostic (8.33e-3)" "unprognostic (5.99e-2)" "unprognostic (2.37e-1)" "unprognostic (1.15e-1)" NAT1 AAC1 ENSG00000171428 "N-acetyltransferase 1" P18440 8 18170477-18223689 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Colonocytes: 30.0;Enterocytes: 27.8;Epididymal principal cells: 26.8;Hepatocytes: 47.5;Proximal tubule cells: 35.0;Respiratory ciliated cells: 176.1" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 5.7" "Cancer enriched" "Detected in all" 18 "Breast Invasive Carcinoma (TCGA): 140.9" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells" "CAB017782, HPA043704" Approved NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 17: Intestine - Digestion" "Cluster 30: White matter - Myelination" "Cluster 27: Breast cancer - Unknown function" "Cluster 107: Ciliated cells - Cilia assembly & function" 3 "CAB017782: , HPA043704: " "unprognostic (8.31e-2)" "unprognostic (1.92e-1)" "unprognostic (1.48e-1)" "unprognostic (3.52e-2)" "potential prognostic favorable (1.22e-6)" "unprognostic (3.22e-3)" "unprognostic (1.44e-2)" "unprognostic (2.74e-2)" "unprognostic (1.16e-1)" "unprognostic (8.36e-2)" "unprognostic (2.85e-3)" "unprognostic (4.60e-1)" "unprognostic (2.83e-1)" "unprognostic (2.03e-1)" "unprognostic (1.12e-3)" "unprognostic (4.17e-2)" "unprognostic (3.97e-2)" "unprognostic (2.02e-1)" "unprognostic (1.54e-1)" "unprognostic (2.36e-2)" "unprognostic (3.02e-3)" "unprognostic (4.24e-2)" "unprognostic (1.97e-1)" "unprognostic (2.42e-1)" "unprognostic (9.38e-2)" "unprognostic (1.10e-2)" "unprognostic (4.07e-3)" "unprognostic (1.33e-1)" "unprognostic (4.01e-2)" "unprognostic (3.38e-2)" "unprognostic (1.80e-1)" NAT10 "FLJ10774, FLJ12179, hALP, KIAA1709, Kre33, NET43" ENSG00000135372 "N-acetyltransferase 10" Q9H0A0 11 34105617-34147670 "Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "rRNA processing, tRNA processing" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - B-cells (Spleen), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB035546, HPA057576, HPA071628" Approved Enhanced Nucleoli,Midbody Yes No 54000 "Cluster 30: Non-specific - DNA binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 24: Neurons - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 88 Nucleoli Midbody "CAB035546: , HPA057576: , HPA071628: " "unprognostic (3.62e-2)" "unprognostic (2.43e-1)" "unprognostic (1.56e-1)" "unprognostic (2.03e-2)" "unprognostic (3.79e-2)" "unprognostic (1.34e-1)" "unprognostic (2.17e-2)" "unprognostic (3.79e-1)" "potential prognostic unfavorable (5.30e-5)" "unprognostic (5.32e-3)" "unprognostic (3.44e-1)" "unprognostic (9.97e-2)" "unprognostic (2.35e-1)" "potential prognostic unfavorable (3.48e-9)" "unprognostic (2.58e-3)" "unprognostic (6.40e-2)" "potential prognostic unfavorable (7.49e-7)" "unprognostic (3.58e-2)" "unprognostic (1.38e-1)" "unprognostic (1.27e-1)" "unprognostic (8.31e-2)" "unprognostic (5.30e-3)" "unprognostic (2.18e-2)" "unprognostic (2.41e-1)" "unprognostic (5.39e-2)" "unprognostic (7.98e-2)" "unprognostic (4.02e-1)" "unprognostic (1.25e-1)" "unprognostic (6.36e-2)" "unprognostic (2.20e-1)" "unprognostic (5.85e-2)" NAT14 KLP1 ENSG00000090971 "N-acetyltransferase 14 (putative)" Q8WUY8 19 55485188-55487568 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" "Activator, Acyltransferase, DNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 66.2" "Cell type enhanced" "Detected in many" "Ependymal cells: 50.2;Epididymal efferent duct ciliated cells: 68.8;Fallopian tube ciliated cells: 90.9;Pancreatic islet cells: 46.5;Respiratory ciliated cells: 77.6;Retinal amacrine cells: 55.3;Retinal horizontal cells: 72.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047187 Approved Mitochondria NA NA "Cluster 65: Brain - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 4: Non-specific - Transcription" "Cluster 109: Neurons - Neuronal signaling" 8 Mitochondria "HPA047187: " "unprognostic (4.93e-2)" "unprognostic (4.18e-2)" "unprognostic (2.96e-2)" "potential prognostic unfavorable (2.18e-4)" "unprognostic (9.93e-2)" "unprognostic (5.95e-2)" "unprognostic (2.16e-1)" "unprognostic (2.64e-2)" "unprognostic (5.86e-2)" "unprognostic (1.05e-1)" "unprognostic (1.12e-3)" "unprognostic (1.88e-2)" "unprognostic (2.03e-3)" "unprognostic (1.04e-2)" "unprognostic (9.56e-2)" "unprognostic (2.14e-1)" "unprognostic (3.24e-1)" "unprognostic (1.04e-1)" "unprognostic (2.91e-1)" "unprognostic (1.70e-1)" "unprognostic (2.48e-1)" "unprognostic (2.18e-2)" "unprognostic (1.27e-2)" "unprognostic (1.79e-1)" "unprognostic (2.85e-1)" "unprognostic (9.09e-2)" "unprognostic (8.85e-2)" "unprognostic (3.33e-3)" "unprognostic (1.02e-1)" "unprognostic (4.89e-2)" "unprognostic (1.89e-1)" NAT16 "C7orf52, FLJ39237" ENSG00000167011 "N-acetyltransferase 16 (putative)" Q8N8M0 7 101170496-101180293 "Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 4.5;pancreas: 2.2;pituitary gland: 3.5;retina: 6.4;thyroid gland: 1.6" "Cell type enriched" "Detected in some" 19 "Retinal horizontal cells: 238.4" "Cell type enhanced" "Detected in many" "LAMP5-LHX6 and Chandelier: 8.2" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 3.8;Skin Cutaneous Melanoma (TCGA): 5.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 4.2" "Adrenal gland - Adrenal medulla cells, Pancreas - Beta cells" HPA021918 Uncertain Approved Nucleoplasm NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 109: Neurons - Neuronal signaling" Nucleoplasm "HPA021918: " "unprognostic (6.42e-2)" "unprognostic (6.82e-3)" "unprognostic (7.69e-2)" "unprognostic (1.45e-2)" "potential prognostic favorable (5.24e-5)" "unprognostic (2.79e-1)" "potential prognostic unfavorable (2.66e-6)" NAT2 AAC2 ENSG00000156006 "N-acetyltransferase 2" P11245 8 18391282-18401218 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 42 "intestine: 31.5;liver: 120.1" "Cell type enhanced" "Detected in some" "Colonocytes: 16.4;Enteric stem cells: 6.1;Enteric transient amplifying cells: 9.2;Enterocytes: 37.1;Epididymal efferent duct absorptive cells: 13.2;Goblet cells: 9.8;Hepatocytes: 74.1;Paneth cells: 7.7;Tuft cells: 11.5" "Cell type enhanced" "Detected in single" "central nervous system macrophage: 1.2" "Cancer enhanced" "Detected in some" "Colon Adenocarcinoma (TCGA): 6.1;Liver Hepatocellular Carcinoma (TCGA): 6.7;Rectum Adenocarcinoma (TCGA): 5.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "colorectal cancer: 2.2" "Colon - Colon enterocytes, Liver - Hepatocytes, Pituitary gland - Undifferentiated cells (Pituitary gland)" HPA043704 Uncertain NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 93: Hepatocytes - Bile production & excretion" 6 "HPA043704: " "unprognostic (6.74e-3)" "potential prognostic favorable (8.85e-4)" "potential prognostic favorable (2.76e-4)" "unprognostic (1.24e-3)" "unprognostic (8.15e-2)" "unprognostic (1.30e-2)" "unprognostic (4.42e-2)" "potential prognostic favorable (1.96e-5)" "potential prognostic favorable (1.24e-4)" "unprognostic (4.60e-2)" "unprognostic (1.31e-1)" NAT8 "ATase2, GLA, Hcml1, TSC501" ENSG00000144035 "N-acetyltransferase 8 (putative)" Q9UHE5 2 73640723-73642422 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "kidney: 683.0" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 10.6;Enterocytes: 55.8;Epididymal efferent duct absorptive cells: 200.4;Epididymal efferent duct ciliated cells: 13.9;Hepatocytes: 58.7;Proximal tubule cells: 29.2" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Kidney Renal Clear Cell Carcinoma (TCGA): 395.5;Kidney Renal Papillary Cell Carcinoma (TCGA): 294.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 9 "liver cancer: 5.0" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "HPA067855, HPA074519" Supported Supported "Endoplasmic reticulum" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 93: Hepatocytes - Bile production & excretion" 26 "Endoplasmic reticulum" "HPA067855: , HPA074519: " "unprognostic (3.24e-1)" "validated prognostic favorable (3.05e-7)" "validated prognostic favorable (4.01e-5)" "unprognostic (8.27e-3)" "unprognostic (9.88e-2)" "unprognostic (6.56e-3)" NAT8B "CML2, Hcml2, NAT8BP" ENSG00000204872 "N-acetyltransferase 8B (putative, gene/pseudogene)" 2 73700576-73701340 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 24 "intestine: 46.4;kidney: 32.6" "Cell type enhanced" "Detected in some" "Enterocytes: 126.6;Epididymal efferent duct absorptive cells: 67.8;Megakaryocytes: 98.9;Platelets: 396.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.1" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Spleen - Macrophages" "HPA067855, HPA074519" Supported Approved "Endoplasmic reticulum" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 47: Platelets - Hemostasis" "Endoplasmic reticulum" "HPA067855: , HPA074519: " NAT8L "FLJ37478, Hcml3, Shati" ENSG00000185818 "N-acetyltransferase 8 like" Q8N9F0 4 2059327-2069089 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adipose tissue: 40.9;brain: 93.1" "Cell type enhanced" "Detected in many" "Astrocytes: 172.6;Bergmann glia: 47.2;Brain excitatory neurons: 37.3;Brain inhibitory neurons: 38.8;Choroid plexus epithelial cells: 31.2;Ependymal cells: 66.9;Oligodendrocyte progenitor cells: 39.5;Other brain neurons: 32.1;Pituicytes/FSCs: 96.2;Retinal amacrine cells: 37.2;Retinal horizontal cells: 50.1;Retinal pigment epithelial cells: 38.4;Sertoli cells: 33.0" "Cell type enhanced" "Detected in all" "astrocyte: 175.8" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 26.1;Skin Cutaneous Melanoma (TCGA): 22.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Colon enteroendocrine cells, Kidney - Ascending Loop of Henle cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Skin - Adipocytes (Skin), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040677 Approved Mitochondria NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 2 Mitochondria "HPA040677: " "unprognostic (2.30e-2)" "unprognostic (2.18e-1)" "unprognostic (2.51e-1)" "unprognostic (1.51e-1)" "unprognostic (2.42e-1)" "unprognostic (5.47e-2)" "unprognostic (1.31e-2)" "unprognostic (3.38e-1)" "unprognostic (2.47e-2)" "unprognostic (3.75e-2)" "unprognostic (1.17e-1)" "unprognostic (1.22e-1)" "unprognostic (2.42e-3)" "unprognostic (1.46e-2)" "unprognostic (2.22e-2)" NAT9 DKFZP564C103 ENSG00000109065 "N-acetyltransferase 9 (putative)" Q9BTE0 17 74770529-74776367 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021820, HPA057149" Approved Approved Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 25: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 7: Non-specific - Transcription" 2 Nucleoplasm "HPA021820: , HPA057149: " "unprognostic (3.04e-2)" "unprognostic (1.51e-1)" "unprognostic (1.40e-2)" "unprognostic (1.56e-2)" "unprognostic (3.38e-2)" "unprognostic (7.45e-2)" "unprognostic (1.23e-1)" "unprognostic (2.11e-2)" "unprognostic (9.69e-2)" "unprognostic (4.32e-2)" "unprognostic (1.00e-2)" "unprognostic (1.87e-2)" "unprognostic (1.58e-1)" "validated prognostic unfavorable (1.02e-6)" "validated prognostic unfavorable (9.44e-4)" "unprognostic (2.68e-1)" "unprognostic (2.80e-2)" "unprognostic (7.74e-2)" "unprognostic (4.33e-2)" "unprognostic (1.05e-1)" "unprognostic (8.68e-3)" "unprognostic (1.07e-3)" "potential prognostic unfavorable (7.44e-4)" "unprognostic (4.61e-3)" "unprognostic (3.82e-3)" "unprognostic (1.38e-1)" "unprognostic (1.44e-2)" "unprognostic (2.46e-2)" "unprognostic (3.47e-1)" "unprognostic (1.05e-1)" "unprognostic (3.77e-2)" NATD1 "C17orf103, Gtlf3b, MGC33894" ENSG00000274180 "N-acetyltransferase domain containing 1" Q8N6N6 17 21238870-21253410 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 37.6" "Cell type enhanced" "Detected in many" "Early spermatids: 56.6;Endometrial glandular cells: 30.0;Erythrocytes: 50.5;Late spermatids: 77.3;Neutrophils: 54.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 5.2" "Group enriched" "Detected in many" 4 "granulocytes: 5.2;monocytes: 1.3" "Cancer enriched" "Detected in all" 6 "testis cancer: 46.2" "Adipose subcutaneous - Adipocytes (Subcutaneous), Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 25: Non-specific - Transcription" "Cluster 47: Leukemia - Hemostasis" "Cluster 24: Neutrophils - Innate immunity signal integration" 7 "unprognostic (5.24e-3)" "unprognostic (1.45e-1)" "unprognostic (4.96e-2)" "unprognostic (6.07e-2)" "unprognostic (3.18e-1)" "unprognostic (6.75e-2)" "unprognostic (3.18e-2)" "unprognostic (4.50e-2)" "validated prognostic favorable (1.54e-5)" "validated prognostic favorable (6.35e-4)" "potential prognostic favorable (5.91e-4)" "unprognostic (6.62e-2)" "unprognostic (3.38e-2)" "unprognostic (1.10e-1)" "unprognostic (6.81e-2)" "unprognostic (1.46e-1)" "unprognostic (1.09e-2)" "unprognostic (6.40e-3)" "unprognostic (1.92e-1)" "unprognostic (1.26e-1)" "unprognostic (3.70e-2)" "unprognostic (4.72e-3)" "unprognostic (1.58e-1)" "unprognostic (6.04e-2)" "unprognostic (1.99e-1)" "unprognostic (2.27e-1)" NAV1 "DKFZp781D0314, FLJ12560, FLJ14203, KIAA1151, MGC14961, POMFIL3, steerin-1" ENSG00000134369 "Neuron navigator 1" Q8NEY1 1 201539127-201826969 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 34.3" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 265.9;Bergmann glia: 409.9;Cardiomyocytes: 433.6;Extravillous trophoblasts: 305.6;Fibro-adipogenic progenitors: 537.9;Myosatellite cells: 506.9;Oligodendrocyte progenitor cells: 891.8;Oligodendrocytes: 297.5;Sertoli cells: 292.8" "Cell type enhanced" "Detected in all" "oligodendrocyte precursor cell: 1015.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 3.4;myeloid DC: 2.1" "Group enriched" "Detected in many" 8 "dendritic cells: 2.1;granulocytes: 3.4" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Liver - Vascular endothelial cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012302, HPA018127, HPA027887" Enhanced Approved Microtubules NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 82: Dendritic cells - Antigen presentation" 17 Microtubules "CAB012302: , HPA018127: , HPA027887: " "unprognostic (2.35e-1)" "unprognostic (3.36e-1)" "unprognostic (5.87e-2)" "unprognostic (1.31e-1)" "unprognostic (1.28e-1)" "unprognostic (2.12e-1)" "unprognostic (8.98e-2)" "unprognostic (2.76e-2)" "unprognostic (5.73e-1)" "potential prognostic unfavorable (7.71e-4)" "unprognostic (7.35e-2)" "unprognostic (1.22e-1)" "potential prognostic unfavorable (4.22e-4)" "unprognostic (9.38e-2)" "unprognostic (7.74e-3)" "unprognostic (1.38e-2)" "unprognostic (1.16e-3)" "unprognostic (2.48e-1)" "unprognostic (1.05e-1)" "unprognostic (2.01e-2)" "unprognostic (1.65e-2)" "unprognostic (9.39e-2)" "unprognostic (1.99e-3)" "unprognostic (1.80e-2)" "unprognostic (1.00e-1)" "unprognostic (2.57e-3)" "unprognostic (4.73e-2)" "unprognostic (4.38e-2)" "unprognostic (1.57e-1)" "unprognostic (2.14e-2)" "unprognostic (4.36e-2)" NAV2 "FLJ10633, FLJ11030, FLJ23707, HELAD1, KIAA1419, POMFIL2, RAINB1" ENSG00000166833 "Neuron navigator 2" Q8IVL1 11 19350724-20121601 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 57.3" "Cell type enhanced" "Detected in many" "Astrocytes: 951.0;Bergmann glia: 837.6;Ependymal cells: 1005.1;Myosatellite cells: 856.3;Oligodendrocyte progenitor cells: 1037.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011755, HPA011891" Approved Supported Nucleoplasm NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 35: Non-specific - Mixed function" "Cluster 44: Non-specific - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 18 Nucleoplasm "HPA011755: , HPA011891: " "unprognostic (2.04e-1)" "unprognostic (1.84e-1)" "unprognostic (7.34e-2)" "unprognostic (8.45e-2)" "unprognostic (1.16e-1)" "unprognostic (1.74e-1)" "unprognostic (2.10e-1)" "unprognostic (2.92e-2)" "potential prognostic favorable (1.81e-4)" "unprognostic (3.38e-2)" "unprognostic (2.33e-2)" "unprognostic (2.53e-2)" "unprognostic (6.24e-2)" "unprognostic (4.53e-2)" "unprognostic (9.76e-2)" "unprognostic (1.64e-1)" "unprognostic (1.58e-2)" "unprognostic (2.46e-2)" "unprognostic (6.17e-2)" "unprognostic (3.11e-1)" "unprognostic (1.41e-1)" "unprognostic (1.48e-3)" "unprognostic (1.33e-1)" "unprognostic (1.58e-1)" "unprognostic (2.88e-2)" "unprognostic (1.88e-1)" "unprognostic (2.63e-1)" "unprognostic (4.62e-2)" "unprognostic (1.00e-1)" "unprognostic (1.83e-1)" "unprognostic (8.96e-3)" NAV3 "KIAA0938, POMFIL1" ENSG00000067798 "Neuron navigator 3" Q8IVL0 12 77324641-78213010 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 15.2;ovary: 14.3" "Cell type enhanced" "Detected in many" "Astrocytes: 1892.0;Brain excitatory neurons: 1486.1;Brain inhibitory neurons: 988.5;Lactotrophs: 2382.7;Microglia: 2147.8;Müller glia: 1074.7;Neutrophil progenitors: 1803.9;Oligodendrocyte progenitor cells: 1325.0;Pituicytes/FSCs: 1197.1;Retinal amacrine cells: 974.5;Retinal horizontal cells: 1769.0;Somatotrophs: 985.2;Thyrotrophs: 1203.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.0" "Lineage enriched" "Detected in single" 9 "granulocytes: 1.0" "Cancer enhanced" "Detected in many" "Rhabdoid: 22.2" "Liver - Hepatic stellate cells, Prostate - Fibroblasts, Spleen - Endothelial cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032111, HPA061392" Approved Approved "Nuclear membrane,Cytosol" NA NA "Cluster 65: Brain - Transcription" "Cluster 53: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 37: Neutrophil progenitors - Granulopoiesis" "Nuclear membrane" Cytosol "HPA032111: , HPA061392: " "unprognostic (1.98e-1)" "unprognostic (4.43e-2)" "unprognostic (2.04e-1)" "unprognostic (2.19e-2)" "unprognostic (2.56e-2)" "unprognostic (3.96e-1)" "unprognostic (2.02e-1)" "unprognostic (1.71e-1)" "potential prognostic favorable (8.38e-6)" "unprognostic (1.41e-1)" "unprognostic (5.82e-2)" "unprognostic (1.61e-1)" "unprognostic (3.79e-1)" "unprognostic (7.39e-3)" "unprognostic (1.99e-1)" "unprognostic (1.86e-3)" "unprognostic (1.31e-1)" "unprognostic (1.06e-3)" "unprognostic (5.29e-2)" NAXD "CARKD, FLJ10769, LP3298" ENSG00000213995 "NAD(P)HX dehydratase" Q8IW45 13 110615545-110639996 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Lyase "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010551 Approved NA NA 210000 "Cluster 33: Non-specific - ATP binding" "Cluster 70: Non-specific - Protein processing" "Cluster 27: Non-specific - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 94: Gonadal somatic cells - Mixed function" 14 "HPA010551: " "unprognostic (4.55e-3)" "unprognostic (6.98e-2)" "unprognostic (7.35e-3)" "unprognostic (3.83e-2)" "unprognostic (1.08e-1)" "unprognostic (1.66e-1)" "unprognostic (1.74e-1)" "unprognostic (1.95e-1)" "unprognostic (3.94e-2)" "potential prognostic favorable (7.34e-4)" "unprognostic (5.09e-3)" "potential prognostic favorable (1.96e-9)" "unprognostic (9.03e-2)" "unprognostic (1.74e-1)" "unprognostic (3.05e-1)" "unprognostic (1.70e-1)" "unprognostic (3.38e-1)" "unprognostic (2.43e-2)" "unprognostic (9.84e-2)" "unprognostic (3.48e-2)" "unprognostic (1.56e-1)" "unprognostic (2.15e-2)" "unprognostic (5.66e-3)" "unprognostic (5.04e-2)" "unprognostic (2.34e-1)" "unprognostic (3.01e-2)" "unprognostic (3.04e-1)" "unprognostic (2.77e-1)" "unprognostic (1.69e-2)" NAXE "AIBP, APOA1BP, MGC119143, MGC119144, MGC119145, YJEFN1" ENSG00000163382 "NAD(P)HX epimerase" Q8NCW5 1 156591756-156609507 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted secreted proteins" "Lipid transport, Transport" Isomerase "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epididymal principal cells: 197.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043766, HPA048164" Enhanced Approved Nucleoplasm,Vesicles,Cytosol "Secreted to blood" Transport NA NA 1200000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 70: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 97: Non-specific - Cellular respiration" 4 Nucleoplasm "Vesicles, Cytosol" "HPA043766: , HPA048164: " "unprognostic (4.67e-2)" "unprognostic (1.31e-1)" "unprognostic (3.72e-2)" "unprognostic (3.99e-3)" "unprognostic (3.31e-2)" "unprognostic (2.39e-2)" "unprognostic (1.53e-1)" "unprognostic (3.04e-3)" "potential prognostic unfavorable (2.37e-4)" "unprognostic (4.37e-2)" "unprognostic (3.45e-2)" "unprognostic (1.68e-2)" "potential prognostic unfavorable (5.02e-4)" "unprognostic (8.28e-2)" "unprognostic (7.73e-2)" "unprognostic (1.11e-1)" "unprognostic (6.75e-2)" "unprognostic (2.25e-2)" "unprognostic (5.78e-2)" "unprognostic (7.63e-2)" "unprognostic (1.02e-1)" "unprognostic (7.84e-3)" "unprognostic (8.41e-2)" "unprognostic (3.07e-1)" "unprognostic (1.41e-1)" "unprognostic (6.09e-2)" "unprognostic (6.30e-2)" "unprognostic (1.26e-1)" "unprognostic (2.96e-1)" NBAS NAG ENSG00000151779 "NBAS subunit of NRZ tethering complex" A2RRP1 2 15166916-15561340 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Endothelial cells, Testis - Early spermatids, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036817 Approved Approved "Nuclear membrane,Nucleoli,Golgi apparatus" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 14: Neurons - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 7: Non-specific - Transcription" 19 "Golgi apparatus" "Nuclear membrane, Nucleoli" "HPA036817: " "unprognostic (6.53e-2)" "unprognostic (2.48e-1)" "unprognostic (3.02e-1)" "unprognostic (2.60e-1)" "unprognostic (3.70e-1)" "unprognostic (2.75e-1)" "unprognostic (1.63e-1)" "unprognostic (1.77e-1)" "unprognostic (2.28e-1)" "unprognostic (2.86e-1)" "unprognostic (3.29e-1)" "unprognostic (3.64e-1)" "unprognostic (4.59e-2)" "potential prognostic unfavorable (6.83e-4)" "unprognostic (1.87e-2)" "unprognostic (3.64e-2)" "unprognostic (5.91e-2)" "potential prognostic favorable (3.62e-4)" "unprognostic (1.47e-2)" "unprognostic (1.71e-2)" "unprognostic (7.03e-2)" "unprognostic (3.41e-3)" "unprognostic (2.46e-2)" "unprognostic (4.00e-2)" "unprognostic (2.06e-1)" "unprognostic (1.41e-1)" "unprognostic (1.08e-1)" "unprognostic (8.88e-2)" "unprognostic (1.96e-1)" "unprognostic (2.69e-1)" "unprognostic (8.95e-2)" NBDY "LINC01420, NoBody" ENSG00000204272 "Negative regulator of P-body association" A0A0U1RRE5 X 56729241-56819179 "Predicted intracellular proteins" "mRNA processing" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 400.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 74: Non-specific - Signal transduction" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 36: Non-specific - mRNA processing" "Cluster 15: Non-specific - Protein processing" 2 "unprognostic (3.04e-1)" "unprognostic (5.96e-3)" "unprognostic (2.70e-2)" "unprognostic (1.28e-1)" "unprognostic (2.68e-1)" "unprognostic (6.47e-2)" "unprognostic (1.84e-1)" "potential prognostic unfavorable (3.80e-4)" "potential prognostic unfavorable (8.65e-4)" "unprognostic (1.56e-2)" "unprognostic (6.57e-2)" "potential prognostic unfavorable (1.78e-5)" "unprognostic (3.24e-3)" "potential prognostic unfavorable (2.28e-4)" "unprognostic (1.12e-2)" "unprognostic (6.74e-3)" "unprognostic (2.44e-1)" "unprognostic (1.45e-1)" "unprognostic (1.33e-1)" "unprognostic (4.66e-2)" "unprognostic (3.09e-2)" "unprognostic (1.73e-1)" "unprognostic (7.01e-2)" "unprognostic (3.69e-1)" "unprognostic (6.49e-2)" "unprognostic (5.10e-3)" "unprognostic (1.79e-1)" "unprognostic (5.18e-2)" "unprognostic (2.44e-3)" NBEA "BCL8B, FLJ10197, KIAA1544, LYST2" ENSG00000172915 Neurobeachin Q8NFP9 13 34942270-35673022 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "retina: 59.2" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 1169.9;Brain inhibitory neurons: 1173.4;Choroid plexus epithelial cells: 1018.9;Cone photoreceptor cells: 931.6;Conjunctival goblet cells: 929.1;Corticotrophs: 1313.4;Gonadotrophs: 861.5;Lactotrophs: 1417.0;Somatotrophs: 910.8;Thyrotrophs: 1000.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Neuroblastoma: 44.6" "Adipose subcutaneous - Smooth muscle cells, Pituitary gland - Lactotropes, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039730, HPA040385" Enhanced Approved "Golgi apparatus,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 42: Retina - Visual perception" "Cluster 37: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" 5 "Golgi apparatus" Cytosol "HPA039730: , HPA040385: " "unprognostic (4.05e-1)" "unprognostic (7.60e-2)" "unprognostic (2.75e-1)" "unprognostic (1.64e-1)" "unprognostic (2.69e-2)" "unprognostic (2.09e-1)" "unprognostic (1.26e-1)" "unprognostic (2.68e-1)" "potential prognostic favorable (9.49e-10)" "unprognostic (5.85e-3)" "unprognostic (2.51e-1)" "unprognostic (2.39e-2)" "unprognostic (4.18e-3)" "unprognostic (9.79e-2)" "unprognostic (1.57e-1)" "unprognostic (3.63e-2)" "unprognostic (5.09e-3)" "unprognostic (1.05e-2)" "unprognostic (3.28e-1)" "unprognostic (5.28e-2)" "unprognostic (2.33e-1)" "unprognostic (6.44e-2)" "unprognostic (8.99e-2)" "unprognostic (2.80e-1)" "unprognostic (1.52e-1)" NBEAL1 "ALS2CR16, ALS2CR17, MGC164581" ENSG00000144426 "Neurobeachin like 1" Q6ZS30 2 203014608-203226378 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Cell type enhanced" "Detected in all" "vascular associated smooth muscle cell: 881.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049189, HPA049447" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 41: Basophils - Unknown function" "Cluster 60: Stomach - Digestion" "Cluster 21: Non-specific - Metabolism" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 110: Mural cells - ECM organization" Nucleoplasm Cytosol "HPA049189: , HPA049447: " "unprognostic (1.80e-1)" "unprognostic (2.66e-2)" "unprognostic (2.66e-1)" "unprognostic (7.94e-3)" "unprognostic (5.97e-2)" "unprognostic (9.93e-3)" "unprognostic (2.20e-1)" "unprognostic (3.49e-2)" "unprognostic (2.65e-2)" "validated prognostic favorable (1.27e-6)" "validated prognostic favorable (2.08e-5)" "unprognostic (2.06e-1)" "unprognostic (1.33e-1)" "unprognostic (3.61e-2)" "unprognostic (2.57e-2)" "unprognostic (2.10e-1)" "unprognostic (2.07e-2)" "unprognostic (4.73e-1)" "unprognostic (7.66e-2)" "unprognostic (9.15e-3)" "unprognostic (1.13e-1)" "unprognostic (1.00e-1)" "unprognostic (1.74e-2)" "unprognostic (2.78e-1)" "unprognostic (8.90e-2)" "unprognostic (1.11e-1)" "unprognostic (8.79e-3)" "unprognostic (1.61e-1)" NBEAL2 KIAA0540 ENSG00000160796 "Neurobeachin like 2" Q6ZNJ1 3 46979666-47009704 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 99.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 210.8;Esophageal apical cells: 141.8;Esophageal suprabasal cells: 94.0;Neutrophil progenitors: 116.9;Neutrophils: 242.7;Renal collecting duct principal cells: 95.4;Salivary duct cells: 88.5" "Cell type enhanced" "Detected in all" "leukocyte: 65.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "neutrophil: 4.4" "Lineage enriched" "Detected in single" 7 "granulocytes: 4.4" "Low cancer specificity" "Detected in all" "Spleen - Neutrophils_2, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051969 Approved NA NA 12000 "Cluster 28: Neutrophils - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 3 "HPA051969: " "unprognostic (7.93e-3)" "unprognostic (7.09e-2)" "unprognostic (1.18e-1)" "unprognostic (3.99e-3)" "unprognostic (6.37e-2)" "unprognostic (5.80e-2)" "unprognostic (1.60e-2)" "unprognostic (7.38e-2)" "unprognostic (4.78e-3)" "unprognostic (6.91e-2)" "unprognostic (2.02e-1)" "unprognostic (1.48e-1)" "unprognostic (1.51e-1)" "potential prognostic unfavorable (4.15e-4)" "unprognostic (3.41e-2)" "unprognostic (3.35e-1)" "unprognostic (9.61e-2)" "unprognostic (6.64e-2)" "unprognostic (1.12e-2)" "unprognostic (4.06e-2)" "unprognostic (3.13e-3)" "unprognostic (5.66e-2)" "unprognostic (6.15e-2)" "unprognostic (2.46e-3)" "unprognostic (1.18e-1)" "unprognostic (4.40e-2)" "unprognostic (8.36e-2)" "unprognostic (8.01e-3)" "unprognostic (2.16e-1)" "unprognostic (6.77e-2)" "unprognostic (2.29e-2)" NBL1 "D1S1733E, DAN, DAND1, NB, NO3" ENSG00000158747 "NBL1, DAN family BMP antagonist" P41271 1 19596979-19658456 "Predicted intracellular proteins, Predicted secreted proteins" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 340.7;Enteric transient amplifying cells: 214.3;Enterocytes: 412.5;Esophageal basal cells: 254.9;Esophageal suprabasal cells: 217.4;Fibroblasts: 247.8;Goblet cells: 201.4;Leydig cells: 306.3;Ovarian stromal cells: 497.1;Peritubular myoid cells: 363.1" "Cell type enhanced" "Detected in all" "fibroblast: 193.3;pericyte: 170.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Liver - Vascular endothelial cells, Lung - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007394, CAB026132" Uncertain "Secreted in other tissues" "No annotated function" NA NA 2300000 "Cluster 11: T-cells - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 94: Gonadal somatic cells - Mixed function" 4 "CAB026132: , HPA007394: " "unprognostic (7.49e-3)" "unprognostic (4.60e-2)" "unprognostic (9.26e-2)" "unprognostic (1.14e-1)" "unprognostic (1.17e-1)" "unprognostic (1.05e-1)" "unprognostic (1.44e-2)" "unprognostic (1.07e-1)" "unprognostic (1.58e-1)" "unprognostic (3.74e-2)" "unprognostic (3.41e-2)" "unprognostic (8.66e-3)" "unprognostic (1.10e-3)" "unprognostic (5.94e-2)" "unprognostic (3.10e-1)" "unprognostic (5.05e-2)" "unprognostic (6.55e-2)" "unprognostic (5.89e-2)" "unprognostic (1.03e-1)" "unprognostic (1.51e-3)" "unprognostic (1.01e-1)" "unprognostic (4.55e-2)" "unprognostic (4.33e-2)" "unprognostic (1.11e-1)" "unprognostic (2.30e-2)" "unprognostic (1.38e-1)" "unprognostic (7.07e-2)" "unprognostic (1.37e-2)" "unprognostic (8.68e-2)" "unprognostic (4.08e-2)" "unprognostic (2.67e-1)" NBN "AT-V1, AT-V2, ATV, NBS, NBS1" ENSG00000104320 Nibrin O60934 8 89924515-90003228 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair, Host-virus interaction, Meiosis" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 372.7;Cardiomyocytes: 1314.0;Neutrophils: 854.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001429, CAB003836, CAB080233" Supported Supported "Nucleoplasm,Mitotic chromosome,Golgi apparatus" Yes NA "Cluster 35: Neutrophils - Protein binding" "Cluster 61: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 40: Non-specific - Unknown function" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 79 Nucleoplasm "Mitotic chromosome, Golgi apparatus" "CAB003836: , CAB080233: , HPA001429: " "unprognostic (1.29e-3)" "unprognostic (1.13e-1)" "unprognostic (2.55e-1)" "unprognostic (3.41e-2)" "unprognostic (3.90e-2)" "unprognostic (1.44e-2)" "unprognostic (1.28e-1)" "unprognostic (3.13e-3)" "unprognostic (7.32e-2)" "unprognostic (6.29e-3)" "potential prognostic favorable (2.17e-4)" "unprognostic (1.85e-2)" "unprognostic (9.17e-2)" "potential prognostic unfavorable (6.03e-4)" "unprognostic (2.92e-2)" "potential prognostic unfavorable (1.51e-6)" "unprognostic (2.04e-2)" "unprognostic (8.16e-2)" "unprognostic (1.60e-1)" "unprognostic (6.57e-3)" "unprognostic (1.19e-2)" "potential prognostic unfavorable (6.15e-4)" "unprognostic (1.49e-2)" "unprognostic (7.70e-2)" "unprognostic (2.50e-2)" "unprognostic (4.73e-2)" "unprognostic (1.29e-2)" "unprognostic (1.48e-1)" "unprognostic (2.45e-1)" "unprognostic (7.81e-3)" "unprognostic (1.79e-1)" NBPF1 "FLJ20719, KIAA1693" ENSG00000219481 "NBPF member 1" Q3BBV0 1 16562319-16613562 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 82.5;Early primary spermatocytes: 65.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 1.2" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "HPA038748, HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050" Approved Approved "Golgi apparatus,Vesicles,Microtubules,Cytokinetic bridge,Primary cilium,Cytosol,Mid piece,Principal piece,End piece" Yes NA "Cluster 45: Eosinophils - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 30: White matter - Myelination" "Cluster 72: Neuronal - Signal transduction" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 1 "Primary cilium, Cytosol" "Golgi apparatus, Vesicles, Microtubules, Cytokinetic bridge, Mid piece, Principal piece, End piece" "HPA038748: , HPA042595: , HPA043105: , HPA043692: , HPA044023: , HPA046971: , HPA058050: " "unprognostic (9.31e-2)" "unprognostic (2.37e-2)" "unprognostic (4.20e-1)" "unprognostic (1.93e-2)" "unprognostic (8.88e-2)" "unprognostic (2.33e-1)" "unprognostic (2.83e-1)" "unprognostic (2.47e-2)" "validated prognostic favorable (1.27e-8)" "validated prognostic favorable (6.73e-4)" "unprognostic (4.99e-3)" "unprognostic (1.09e-1)" "potential prognostic favorable (9.29e-4)" "unprognostic (8.21e-2)" "unprognostic (5.55e-2)" "unprognostic (1.97e-2)" "unprognostic (1.13e-1)" "unprognostic (1.63e-1)" "unprognostic (2.97e-2)" "unprognostic (1.13e-1)" "unprognostic (2.35e-2)" "unprognostic (3.36e-2)" "unprognostic (3.75e-1)" "unprognostic (5.65e-2)" "unprognostic (1.23e-1)" "unprognostic (1.24e-1)" "unprognostic (7.77e-3)" "unprognostic (6.29e-3)" NBPF10 AG1 ENSG00000271425 "NBPF member 10" Q6P3W6 1 146064711-146229000 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Neutrophils: 32.0;Paneth cells: 30.9;Sertoli cells: 36.2" "Cell type enhanced" "Detected in many" "Bergmann glia: 22.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "HPA038748, HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050" Approved Approved "Golgi apparatus,Vesicles,Microtubules,Cytokinetic bridge,Primary cilium,Cytosol,Mid piece,Principal piece,End piece" Yes NA "Cluster 7: Non-specific - Innate immune response" "Cluster 40: Non-specific - Mixed function" "Cluster 12: Non-specific - Vasculature" "Cluster 45: Non-specific - Nuclear processes" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" "Primary cilium, Cytosol" "Golgi apparatus, Vesicles, Microtubules, Cytokinetic bridge, Mid piece, Principal piece, End piece" "HPA038748: , HPA042595: , HPA043105: , HPA043692: , HPA044023: , HPA046971: , HPA058050: " "unprognostic (1.09e-1)" "unprognostic (2.13e-1)" "unprognostic (1.02e-1)" "unprognostic (2.56e-2)" "unprognostic (1.83e-1)" "unprognostic (3.31e-3)" "unprognostic (6.70e-3)" "unprognostic (8.03e-3)" "unprognostic (5.19e-2)" "unprognostic (8.01e-2)" "unprognostic (1.20e-1)" "unprognostic (1.89e-2)" "unprognostic (2.83e-1)" "unprognostic (2.42e-1)" "unprognostic (1.87e-3)" "unprognostic (4.10e-2)" "unprognostic (1.31e-1)" "unprognostic (2.45e-1)" "unprognostic (1.51e-1)" "unprognostic (1.71e-1)" "unprognostic (1.54e-1)" NBPF11 NBPF24 ENSG00000263956 "NBPF member 11" Q86T75 1 148102047-148152322 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "HPA038748, HPA038752, HPA042595, HPA043105, HPA044023, HPA046971, HPA058050" Uncertain Approved "Golgi apparatus,Vesicles,Microtubules,Cytokinetic bridge,Primary cilium,Cytosol,Mid piece,Principal piece,End piece" Yes NA "Cluster 22: Eosinophils - Transcription" "Cluster 70: Non-specific - Protein processing" "Cluster 30: White matter - Myelination" "Cluster 45: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" 1 "Primary cilium, Cytosol" "Golgi apparatus, Vesicles, Microtubules, Cytokinetic bridge, Mid piece, Principal piece, End piece" "HPA038748: , HPA038752: , HPA042595: , HPA043105: , HPA044023: , HPA046971: , HPA058050: " "unprognostic (1.18e-1)" "unprognostic (1.29e-1)" "unprognostic (5.12e-3)" "unprognostic (2.78e-2)" "unprognostic (1.25e-1)" "unprognostic (6.52e-2)" "unprognostic (6.47e-3)" "unprognostic (1.07e-2)" "unprognostic (8.25e-2)" "unprognostic (3.37e-2)" "unprognostic (2.30e-1)" "unprognostic (2.89e-2)" "unprognostic (3.28e-3)" "unprognostic (1.41e-1)" "unprognostic (1.03e-1)" "unprognostic (1.44e-2)" "unprognostic (1.80e-1)" "unprognostic (1.01e-3)" "unprognostic (5.91e-2)" "unprognostic (1.05e-2)" "unprognostic (1.27e-1)" "unprognostic (3.78e-1)" "unprognostic (2.25e-1)" "unprognostic (2.59e-1)" "unprognostic (2.36e-1)" "unprognostic (1.76e-2)" NBPF12 "COAS1, KIAA1245" ENSG00000268043 "NBPF member 12" Q5TAG4 1 146938324-146996202 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "pancreas: 54.7;stomach 1: 40.6" "Group enriched" "Detected in many" 4 "Gastric chief cells: 564.6;Mucous neck cells: 247.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "HPA038748, HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050" Approved Approved "Golgi apparatus,Vesicles,Microtubules,Cytokinetic bridge,Primary cilium,Cytosol,Mid piece,Principal piece,End piece" Yes NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 8: Pancreas - Proteolysis" "Cluster 30: White matter - Myelination" "Cluster 45: Non-specific - Nuclear processes" "Cluster 97: Non-specific - Cellular respiration" "Primary cilium, Cytosol" "Golgi apparatus, Vesicles, Microtubules, Cytokinetic bridge, Mid piece, Principal piece, End piece" "HPA038748: , HPA042595: , HPA043105: , HPA043692: , HPA044023: , HPA046971: , HPA058050: " "unprognostic (6.02e-2)" "unprognostic (9.57e-2)" "unprognostic (1.58e-1)" "unprognostic (1.91e-1)" "unprognostic (1.36e-1)" "unprognostic (2.66e-2)" "unprognostic (2.38e-3)" "unprognostic (1.42e-2)" "unprognostic (2.27e-2)" "potential prognostic favorable (9.11e-4)" "unprognostic (3.11e-1)" "unprognostic (8.49e-3)" "unprognostic (6.41e-2)" "unprognostic (2.07e-1)" "unprognostic (1.85e-1)" "unprognostic (5.62e-3)" "unprognostic (4.24e-2)" "unprognostic (1.14e-3)" "unprognostic (2.05e-1)" "unprognostic (1.79e-2)" "unprognostic (8.30e-2)" "unprognostic (9.47e-2)" "unprognostic (2.21e-2)" "unprognostic (2.18e-1)" "unprognostic (1.01e-1)" "unprognostic (9.86e-2)" NBPF14 DJ328E19.C1.1 ENSG00000270629 "NBPF member 14" 1 148531385-148679742 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 68.6;Podocytes: 91.4;Sertoli cells: 88.0;Suprabasal keratinocytes: 65.8" "Cell type enhanced" "Detected in many" "Bergmann glia: 26.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "HPA038748, HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050" Uncertain Approved "Golgi apparatus,Vesicles,Microtubules,Cytokinetic bridge,Primary cilium,Cytosol,Mid piece,Principal piece,End piece" Yes NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 40: Non-specific - Mixed function" "Cluster 12: Non-specific - Vasculature" "Cluster 45: Non-specific - Nuclear processes" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" "Primary cilium, Cytosol" "Golgi apparatus, Vesicles, Microtubules, Cytokinetic bridge, Mid piece, Principal piece, End piece" "HPA038748: , HPA042595: , HPA043105: , HPA043692: , HPA044023: , HPA046971: , HPA058050: " "unprognostic (8.53e-3)" "unprognostic (1.12e-1)" "unprognostic (8.00e-2)" "unprognostic (5.21e-2)" "unprognostic (7.48e-2)" "unprognostic (6.07e-2)" "unprognostic (2.64e-2)" "unprognostic (2.02e-3)" "unprognostic (8.36e-2)" "validated prognostic favorable (3.68e-4)" "validated prognostic favorable (8.95e-4)" "unprognostic (1.90e-1)" "unprognostic (2.55e-1)" "unprognostic (8.06e-2)" "unprognostic (8.26e-2)" "unprognostic (7.83e-3)" "unprognostic (3.50e-1)" "unprognostic (2.56e-1)" "potential prognostic unfavorable (1.79e-4)" "unprognostic (1.02e-2)" "unprognostic (1.48e-1)" "unprognostic (1.39e-1)" "unprognostic (8.02e-2)" "unprognostic (3.92e-1)" "unprognostic (3.49e-1)" "unprognostic (1.46e-1)" "unprognostic (3.99e-1)" "unprognostic (5.02e-3)" NBPF15 "MGC8902, NBPF16" ENSG00000266338 "NBPF member 15" Q8N660 1 144421390-144461676 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 2.6;NK-cells: 2.3;T-cells: 3.9" "Low cancer specificity" "Detected in all" "HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050" Approved Approved "Golgi apparatus,Vesicles,Microtubules,Cytokinetic bridge,Primary cilium,Cytosol,Mid piece,Principal piece,End piece" Yes NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 64: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 45: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" "Primary cilium, Cytosol" "Golgi apparatus, Vesicles, Microtubules, Cytokinetic bridge, Mid piece, Principal piece, End piece" "HPA042595: , HPA043105: , HPA043692: , HPA044023: , HPA046971: , HPA058050: " "unprognostic (2.08e-2)" "unprognostic (6.58e-2)" "unprognostic (2.35e-1)" "unprognostic (2.72e-2)" "unprognostic (7.44e-2)" "unprognostic (8.85e-3)" "unprognostic (2.26e-1)" "unprognostic (1.52e-2)" "unprognostic (7.17e-2)" "unprognostic (6.12e-2)" "unprognostic (1.75e-1)" "unprognostic (3.22e-2)" "unprognostic (1.80e-3)" "unprognostic (3.79e-3)" "unprognostic (2.26e-1)" "unprognostic (3.47e-2)" "unprognostic (3.73e-2)" "unprognostic (1.94e-1)" "unprognostic (7.20e-2)" "unprognostic (2.07e-2)" "unprognostic (2.59e-3)" "unprognostic (2.14e-1)" "unprognostic (3.44e-2)" "unprognostic (1.27e-1)" "unprognostic (1.40e-1)" "unprognostic (1.72e-1)" "unprognostic (1.57e-1)" "unprognostic (1.38e-1)" NBPF19 ENSG00000271383 "NBPF member 19" A0A087WUL8 1 149475045-149556361 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 33.8;Bergmann glia: 28.8;Distal convoluted tubule cells: 28.6;Loop of henle epithelial cells: 29.9;Papillary tip epithelial cells: 25.9;Podocytes: 95.0;Proximal tubule cells: 24.0;Renal collecting duct intercalated cells: 15.8;Renal collecting duct principal cells: 31.8;Renal connecting tubule cells: 33.2" "Cell type enhanced" "Detected in many" "astrocyte: 26.3;Bergmann glia: 23.5;leukocyte: 21.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050" Uncertain Approved "Golgi apparatus,Vesicles,Microtubules,Cytokinetic bridge,Primary cilium,Cytosol,Mid piece,Principal piece,End piece" Yes NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 40: Non-specific - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 105: Non-specific - Mixed function" "Primary cilium, Cytosol" "Golgi apparatus, Vesicles, Microtubules, Cytokinetic bridge, Mid piece, Principal piece, End piece" "HPA042595: , HPA043105: , HPA043692: , HPA044023: , HPA046971: , HPA058050: " "unprognostic (3.80e-3)" "unprognostic (1.80e-1)" "unprognostic (3.21e-1)" "unprognostic (6.54e-2)" "unprognostic (3.03e-1)" "unprognostic (2.19e-2)" "unprognostic (8.97e-3)" "unprognostic (1.96e-1)" "unprognostic (1.06e-3)" "unprognostic (1.32e-3)" "unprognostic (7.33e-2)" "unprognostic (8.18e-2)" "unprognostic (1.90e-1)" "unprognostic (7.16e-2)" "unprognostic (6.13e-2)" "unprognostic (2.20e-1)" "unprognostic (2.93e-3)" "unprognostic (2.50e-2)" "unprognostic (2.67e-1)" "unprognostic (6.55e-2)" "unprognostic (2.72e-2)" "unprognostic (3.79e-1)" "unprognostic (4.20e-2)" "unprognostic (3.53e-1)" "unprognostic (8.62e-2)" "unprognostic (2.53e-2)" NBPF20 ENSG00000162825 "NBPF member 20" 1 145289900-145425603 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.6" "Cell type enhanced" "Detected in many" "Hepatocytes: 40.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen), Testis - Early spermatids" "HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050" Uncertain Approved "Golgi apparatus,Vesicles,Microtubules,Cytokinetic bridge,Primary cilium,Cytosol,Mid piece,Principal piece,End piece" Yes NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 27: Cerebellum - Synaptic function" "Cluster 35: Non-specific - DNA binding" "Cluster 45: Non-specific - Nuclear processes" "Cluster 18: Adrenal cortex cells - Steroidogensis" "Primary cilium, Cytosol" "Golgi apparatus, Vesicles, Microtubules, Cytokinetic bridge, Mid piece, Principal piece, End piece" "HPA042595: , HPA043105: , HPA043692: , HPA044023: , HPA046971: , HPA058050: " "potential prognostic unfavorable (4.46e-4)" "unprognostic (1.05e-2)" "unprognostic (1.03e-2)" "unprognostic (2.01e-1)" "unprognostic (8.53e-2)" "unprognostic (1.76e-2)" "unprognostic (7.47e-2)" "unprognostic (1.06e-3)" "potential prognostic favorable (1.81e-4)" "unprognostic (1.90e-1)" "unprognostic (5.85e-2)" "unprognostic (8.83e-2)" "unprognostic (6.74e-2)" "unprognostic (2.54e-1)" "unprognostic (1.73e-3)" "unprognostic (7.54e-2)" "unprognostic (2.56e-2)" "unprognostic (1.59e-1)" "unprognostic (2.41e-2)" "unprognostic (2.33e-1)" "unprognostic (8.94e-2)" "unprognostic (1.65e-1)" "unprognostic (2.37e-1)" "unprognostic (1.05e-1)" "unprognostic (3.35e-1)" "unprognostic (7.07e-3)" "unprognostic (4.94e-2)" NBPF26 ENSG00000273136 "NBPF member 26" 1 120723949-120842110 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 72.7;Podocytes: 49.6;Sertoli cells: 72.7" "Cell type enhanced" "Detected in many" "astrocyte: 32.8;Bergmann glia: 40.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "granulocytes: 7.3;monocytes: 5.7" "Low cancer specificity" "Detected in all" "HPA038748, HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050" Uncertain Approved "Golgi apparatus,Vesicles,Microtubules,Cytokinetic bridge,Primary cilium,Cytosol,Mid piece,Principal piece,End piece" Yes NA "Cluster 21: Neutrophils - Unknown function" "Cluster 58: Skin - Keratinization" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 32: Non-specific - Cell proliferation" "Cluster 24: Neutrophils - Innate immunity signal integration" "Primary cilium, Cytosol" "Golgi apparatus, Vesicles, Microtubules, Cytokinetic bridge, Mid piece, Principal piece, End piece" "HPA038748: , HPA042595: , HPA043105: , HPA043692: , HPA044023: , HPA046971: , HPA058050: " "unprognostic (3.92e-2)" "unprognostic (1.04e-1)" "unprognostic (5.29e-3)" "unprognostic (8.28e-2)" "unprognostic (1.03e-1)" "unprognostic (2.94e-1)" "unprognostic (3.29e-3)" "unprognostic (1.38e-2)" "unprognostic (3.39e-2)" "unprognostic (3.09e-2)" "unprognostic (9.03e-2)" "unprognostic (1.75e-1)" "unprognostic (1.31e-1)" "unprognostic (8.70e-3)" "unprognostic (2.71e-2)" "unprognostic (6.44e-2)" "unprognostic (6.34e-3)" "unprognostic (8.19e-2)" "unprognostic (6.41e-2)" "potential prognostic favorable (3.14e-4)" "unprognostic (2.98e-3)" "unprognostic (1.14e-1)" "unprognostic (1.17e-1)" "unprognostic (1.70e-1)" "unprognostic (1.14e-1)" "unprognostic (1.88e-2)" NBPF3 AE2 ENSG00000142794 "NBPF member 3" Q9H094 1 21440128-21485005 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "testis: 9.1" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 98.6;Early primary spermatocytes: 46.0;Leydig cells: 44.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" "HPA042595, HPA043692, HPA044023, HPA046971, HPA058050, HPA073664" Approved Approved "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 27: T-cells - Unknown function" "Cluster 67: Testis - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 18: Adrenal cortex cells - Steroidogensis" "Nucleoplasm, Cytosol" "Nuclear speckles" "HPA042595: , HPA043692: , HPA044023: , HPA046971: , HPA058050: , HPA073664: " "potential prognostic favorable (9.12e-4)" "unprognostic (3.76e-2)" "unprognostic (1.88e-1)" "unprognostic (1.38e-2)" "unprognostic (1.75e-3)" "unprognostic (2.80e-1)" "unprognostic (7.35e-2)" "unprognostic (6.09e-2)" "unprognostic (9.45e-2)" "unprognostic (7.26e-3)" "unprognostic (7.88e-2)" "unprognostic (3.10e-1)" "unprognostic (7.19e-3)" "unprognostic (1.72e-1)" "unprognostic (2.23e-2)" "unprognostic (2.90e-1)" "unprognostic (1.88e-1)" "potential prognostic favorable (3.29e-4)" "unprognostic (2.05e-1)" "unprognostic (3.29e-1)" "unprognostic (3.07e-1)" "unprognostic (5.39e-3)" "unprognostic (5.39e-2)" "unprognostic (1.63e-1)" "unprognostic (3.03e-1)" NBPF4 FLJ32833 ENSG00000196427 "NBPF member 4" Q96M43 1 108222464-108244081 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "intestine: 1.2;testis: 4.1" "Cell type enhanced" "Detected in some" "Goblet cells: 1.9;Gonadotrophs: 3.1;Late primary spermatocytes: 8.5;Late spermatids: 1.6" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Breast Invasive Carcinoma (TCGA): 5.3" "Region enhanced" "Detected in some" "basal ganglia: 2.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 3.2" "Testis - Early spermatids" "HPA045044, HPA046411, HPA047447, HPA058050" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 21: Testis - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" "Nucleoplasm, Cytosol" "HPA045044: , HPA046411: , HPA047447: , HPA058050: " "unprognostic (2.13e-1)" "unprognostic (3.44e-1)" "unprognostic (5.97e-2)" NBPF6 ENSG00000186086 "NBPF member 6" Q5VWK0 1 108450282-108471920 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "liver: 2.6;testis: 2.5" "Cell type enhanced" "Detected in single" "Late primary spermatocytes: 2.3" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "Breast Invasive Carcinoma (TCGA): 3.6" "Region enhanced" "Detected in some" "basal ganglia: 4.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Breast - Breast glandular cells, Testis - Early spermatids" "HPA045044, HPA046411, HPA047447, HPA058050" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 47: Testis - Mixed function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" "Nucleoplasm, Cytosol" "HPA045044: , HPA046411: , HPA047447: , HPA058050: " "unprognostic (3.18e-2)" "unprognostic (2.04e-1)" "unprognostic (9.50e-3)" NBPF8 NBPF8P ENSG00000270231 "NBPF member 8" 1 120415035-120469676 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 52.3;Epicardial cells: 54.6;Fibro-adipogenic progenitors: 44.8" "Low cell type specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "HPA038748, HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050" Uncertain Approved "Golgi apparatus,Vesicles,Microtubules,Cytokinetic bridge,Primary cilium,Cytosol,Mid piece,Principal piece,End piece" Yes NA "Cluster 70: Non-specific - Protein processing" "Cluster 15: Non-specific - Transcription" "Cluster 56: Non-specific - Sensory perception" "Cluster 108: Fibroblasts - ECM organization" "Primary cilium, Cytosol" "Golgi apparatus, Vesicles, Microtubules, Cytokinetic bridge, Mid piece, Principal piece, End piece" "HPA038748: , HPA042595: , HPA043105: , HPA043692: , HPA044023: , HPA046971: , HPA058050: " NBPF9 AE01 ENSG00000269713 "NBPF member 9" P0DPF3 1 149052186-149103561 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibro-adipogenic progenitors: 32.6;Hepatocytes: 33.9;Podocytes: 39.5;Sertoli cells: 26.8" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA038748, HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050" Approved Approved "Golgi apparatus,Vesicles,Microtubules,Cytokinetic bridge,Cytosol,Mid piece,Principal piece,End piece" Yes NA "Cluster 20: Non-specific - DNA binding" "Cluster 40: Non-specific - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 105: Non-specific - Mixed function" Cytosol "Golgi apparatus, Vesicles, Microtubules, Cytokinetic bridge, Mid piece, Principal piece, End piece" "HPA038748: , HPA042595: , HPA043105: , HPA043692: , HPA044023: , HPA046971: , HPA058050: " "potential prognostic unfavorable (8.33e-4)" "unprognostic (6.34e-2)" "unprognostic (1.62e-1)" "unprognostic (8.48e-2)" "unprognostic (1.50e-1)" "unprognostic (8.26e-2)" "unprognostic (4.08e-1)" "unprognostic (7.39e-2)" "unprognostic (7.27e-2)" "unprognostic (7.41e-2)" "unprognostic (1.02e-1)" "unprognostic (1.21e-1)" "unprognostic (2.38e-2)" "unprognostic (8.38e-3)" "unprognostic (2.43e-1)" "unprognostic (2.32e-1)" "unprognostic (4.23e-2)" "unprognostic (2.82e-1)" "unprognostic (5.34e-2)" "unprognostic (9.97e-2)" "unprognostic (6.43e-2)" "unprognostic (2.90e-2)" "unprognostic (2.13e-1)" "unprognostic (1.14e-2)" "unprognostic (1.42e-1)" "unprognostic (1.93e-1)" "unprognostic (2.04e-2)" "unprognostic (1.70e-2)" NBR1 "1A1-3B, CA125, KIAA0049, M17S2" ENSG00000188554 "NBR1 autophagy cargo receptor" Q14596 17 43170481-43211689 "Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Late spermatids: 1686.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022944, HPA022999, HPA023999" Approved Supported "Nucleoplasm,Nuclear bodies,Vesicles,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 21: Testis - Mixed function" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 52 Vesicles "Nucleoplasm, Nuclear bodies, Cytosol" "HPA022944: , HPA022999: , HPA023999: " "unprognostic (9.66e-2)" "unprognostic (1.48e-2)" "unprognostic (3.54e-1)" "unprognostic (4.07e-2)" "unprognostic (8.28e-2)" "unprognostic (1.34e-1)" "unprognostic (1.15e-1)" "unprognostic (1.19e-1)" "unprognostic (1.19e-1)" "unprognostic (3.54e-3)" "validated prognostic favorable (1.59e-9)" "validated prognostic favorable (3.35e-6)" "unprognostic (1.53e-1)" "unprognostic (1.13e-1)" "unprognostic (2.10e-1)" "unprognostic (8.25e-2)" "unprognostic (7.05e-2)" "unprognostic (2.92e-2)" "unprognostic (3.72e-1)" "unprognostic (3.17e-3)" "potential prognostic unfavorable (5.02e-4)" "unprognostic (1.63e-2)" "unprognostic (8.74e-2)" "unprognostic (9.00e-2)" "unprognostic (4.79e-3)" "unprognostic (1.69e-1)" "unprognostic (4.34e-2)" "unprognostic (1.22e-1)" "unprognostic (1.50e-1)" "unprognostic (5.68e-2)" "unprognostic (5.85e-2)" NCALD ENSG00000104490 "Neurocalcin delta" P61601 8 101686542-102124907 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 113.1;salivary gland: 94.5" "Cell type enhanced" "Detected in many" "Innate lymphoid cells: 535.9;Lacrimal acinar cells: 653.1;NK-cells: 627.4;Oligodendrocyte progenitor cells: 580.9;Respiratory ionocytes: 774.7;Salivary acinar cells: 1129.3;Salivary ionocytes: 902.9;Somatotrophs: 580.1;Thyrotrophs: 870.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 87.3" "Group enriched" "Detected in many" 13 "NK-cells: 87.3;T-cells: 42.0" "Cancer enhanced" "Detected in many" "Rhabdoid: 35.5" "Adrenal gland - Fibroblasts, Breast - Breast myoepithelial cells, Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Fibroblasts, Skin - Eccrine sweat gland cells, Spleen - Fibroblasts_1, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043245 Approved NA NA 66000 "Cluster 15: NK-cells - Unknown function" "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 34 "HPA043245: " "unprognostic (3.55e-3)" "unprognostic (3.10e-1)" "unprognostic (9.80e-2)" "unprognostic (3.33e-1)" "unprognostic (2.68e-1)" "unprognostic (4.94e-2)" "unprognostic (5.41e-2)" "unprognostic (6.51e-2)" "potential prognostic favorable (9.03e-4)" "unprognostic (9.31e-3)" "potential prognostic favorable (1.16e-6)" "unprognostic (1.50e-3)" "unprognostic (1.61e-1)" "unprognostic (2.22e-1)" "unprognostic (2.50e-3)" "unprognostic (1.18e-3)" "unprognostic (8.58e-2)" "unprognostic (1.32e-1)" "unprognostic (2.73e-2)" "unprognostic (1.93e-1)" "unprognostic (1.15e-1)" "potential prognostic favorable (4.93e-4)" "unprognostic (2.81e-2)" "unprognostic (1.13e-1)" "unprognostic (1.25e-1)" "unprognostic (1.74e-1)" "unprognostic (2.52e-1)" "unprognostic (1.65e-2)" "unprognostic (2.07e-1)" "unprognostic (4.37e-2)" "unprognostic (1.75e-1)" NCAM1 "CD56, NCAM" ENSG00000149294 "Neural cell adhesion molecule 1" P13591 11 112961247-113278436 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 187.4;heart muscle: 136.4" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 819.0;Astrocytes: 954.9;Bergmann glia: 1167.3;Brain excitatory neurons: 590.3;Brain inhibitory neurons: 699.3;Cardiomyocytes: 1069.7;Lactotrophs: 552.0;Müller glia: 780.8;Oligodendrocyte progenitor cells: 1404.4;Oligodendrocytes: 1441.0;Other brain neurons: 669.6;Retinal amacrine cells: 646.1;Retinal horizontal cells: 635.1;Schwann cells: 580.5;Thymic myoid cells: 749.2;Thyrotrophs: 788.4" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 10 "Glioblastoma Multiforme (TCGA): 129.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 15 "NK-cell: 53.9" "Lineage enriched" "Detected in many" 15 "NK-cells: 53.9" "Cancer enhanced" "Detected in many" "Neuroblastoma: 126.4" "Adipose subcutaneous - Smooth muscle cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000142, CAB018071, HPA039835" Enhanced Enhanced "Plasma membrane,Cytosol" "Secreted in other tissues" Receptor NA NA 300000000 "Cluster 15: NK-cells - Unknown function" "Cluster 35: Non-specific - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 28: Astrocytes - Homeostasis & neuron support" 5 "Plasma membrane" Cytosol "CAB000142: , CAB018071: , HPA039835: " "unprognostic (9.56e-2)" "unprognostic (1.04e-1)" "unprognostic (1.54e-1)" "unprognostic (7.30e-2)" "unprognostic (3.55e-2)" "unprognostic (8.34e-2)" "unprognostic (2.63e-1)" "potential prognostic favorable (1.51e-4)" "unprognostic (5.08e-3)" "unprognostic (3.00e-1)" "unprognostic (9.30e-3)" "unprognostic (1.74e-1)" "unprognostic (2.21e-1)" "unprognostic (7.41e-2)" "unprognostic (3.92e-3)" "unprognostic (2.09e-2)" "unprognostic (7.56e-2)" "unprognostic (4.00e-2)" "unprognostic (3.93e-2)" "unprognostic (8.16e-2)" "potential prognostic favorable (1.08e-4)" "unprognostic (7.84e-2)" "unprognostic (7.01e-2)" "unprognostic (2.56e-1)" "unprognostic (1.64e-2)" "unprognostic (3.33e-1)" "unprognostic (1.16e-2)" "unprognostic (1.40e-1)" "unprognostic (3.22e-2)" "unprognostic (3.74e-2)" NCAM2 "MGC51008, NCAM21" ENSG00000154654 "Neural cell adhesion molecule 2" O15394 21 20998409-21543329 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 11.3;brain: 38.9" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 1097.0;Adrenal medulla cells: 1106.2;Astrocytes: 1271.1;Bergmann glia: 2749.5;Brain excitatory neurons: 1376.0;Brain inhibitory neurons: 926.8;Ependymal cells: 975.9;Oligodendrocyte progenitor cells: 2609.3;Oligodendrocytes: 2578.9;Other brain neurons: 921.1;Schwann cells: 1302.0;Sertoli cells: 1315.1" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Breast Invasive Carcinoma (TCGA): 6.5;Glioblastoma Multiforme (TCGA): 12.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "prostate cancer: 45.3;Rhabdoid: 16.5" "Skeletal muscle - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030900, HPA030901" Enhanced Supported Supported "Nuclear bodies,Plasma membrane" No No 30000000 "Cluster 73: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" "Nuclear bodies, Plasma membrane" "HPA030900: , HPA030901: " "unprognostic (5.71e-2)" "unprognostic (3.28e-2)" "unprognostic (1.38e-1)" "unprognostic (1.41e-1)" "potential prognostic favorable (6.43e-4)" "unprognostic (1.27e-1)" "unprognostic (3.59e-2)" "unprognostic (6.73e-3)" "unprognostic (1.15e-1)" "unprognostic (7.35e-3)" "unprognostic (2.12e-1)" "unprognostic (1.11e-2)" "unprognostic (2.05e-2)" NCAN CSPG3 ENSG00000130287 Neurocan O14594 19 19211958-19252233 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 85 "brain: 98.5" "Cell type enriched" "Detected in some" 4 "Astrocytes: 239.4" "Cell type enhanced" "Detected in many" "astrocyte: 209.1" "Cancer enriched" "Detected in some" 60 "Glioblastoma Multiforme (TCGA): 125.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "breast cancer: 2.7;Neuroblastoma: 8.2" "Colon - Colon enteroendocrine cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036814 Enhanced "Secreted in brain" "Cell adhesion" NA NA 1400000 "Cluster 73: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 28: Astrocytes - Homeostasis & neuron support" "HPA036814: " "unprognostic (1.06e-3)" "unprognostic (3.63e-1)" "unprognostic (6.44e-2)" "unprognostic (6.67e-2)" "unprognostic (1.16e-1)" NCAPD2 "CAP-D2, CNAP1, hCAP-D2, KIAA0159" ENSG00000010292 "Non-SMC condensin I complex subunit D2" Q15021 12 6493356-6531955 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 71.5" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 108.4;Megakaryocyte progenitors: 77.7;Monocyte progenitors: 159.2;Neutrophil progenitors: 126.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012423, HPA036947, HPA037363" Approved Supported "Nucleoplasm,Nucleoli,Primary cilium,Centriolar satellite,Basal body,Cytosol" NA Yes 22000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 11: White matter - Signal transduction" "Cluster 38: Non-specific - Transcription" "Cluster 27: Non-specific - Cell proliferation" 37 "Nucleoplasm, Cytosol" "Nucleoli, Primary cilium, Centriolar satellite, Basal body" "CAB012423: , HPA036947: , HPA037363: " "unprognostic (2.51e-3)" "unprognostic (1.22e-1)" "unprognostic (6.67e-2)" "unprognostic (4.47e-1)" "unprognostic (6.46e-2)" "unprognostic (1.45e-1)" "unprognostic (2.70e-1)" "unprognostic (1.37e-2)" "unprognostic (3.03e-1)" "potential prognostic unfavorable (2.52e-4)" "unprognostic (4.02e-3)" "unprognostic (8.45e-3)" "unprognostic (1.55e-3)" "validated prognostic unfavorable (1.36e-7)" "validated prognostic unfavorable (2.81e-5)" "potential prognostic unfavorable (3.05e-4)" "unprognostic (1.23e-2)" "unprognostic (1.45e-2)" "unprognostic (2.88e-1)" "unprognostic (2.54e-2)" "unprognostic (6.99e-2)" "unprognostic (7.36e-3)" "unprognostic (3.01e-3)" "unprognostic (2.27e-1)" "unprognostic (2.94e-2)" "unprognostic (1.31e-2)" "unprognostic (1.51e-2)" "unprognostic (1.73e-2)" "unprognostic (1.98e-1)" "unprognostic (1.48e-1)" "unprognostic (2.11e-1)" NCAPD3 "CAP-D3, FLJ42888, hCAP-D3, hcp-6, hHCP-6, KIAA0056" ENSG00000151503 "Non-SMC condensin II complex subunit D3" P42695 11 134150113-134225504 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "lymphoid tissue: 17.0;prostate: 52.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 110.2;Erythrocyte progenitors: 146.0;Monocyte progenitors: 100.2;Sertoli cells: 99.1" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 9 "Prostate Adenocarcinoma (TCGA): 128.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040286 Supported Nucleoplasm NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 25 Nucleoplasm "HPA040286: " "unprognostic (3.08e-1)" "potential prognostic unfavorable (5.09e-4)" "unprognostic (2.23e-2)" "unprognostic (1.76e-1)" "potential prognostic unfavorable (4.80e-4)" "unprognostic (2.82e-1)" "unprognostic (2.51e-1)" "unprognostic (3.27e-3)" "unprognostic (3.42e-1)" "unprognostic (9.94e-2)" "unprognostic (1.70e-2)" "unprognostic (1.77e-1)" "unprognostic (1.92e-2)" "unprognostic (4.41e-3)" "unprognostic (1.24e-1)" "unprognostic (3.18e-3)" "unprognostic (5.00e-2)" "unprognostic (1.10e-1)" "unprognostic (9.59e-2)" "unprognostic (2.57e-2)" "unprognostic (6.19e-2)" "unprognostic (7.57e-2)" "unprognostic (1.72e-3)" "unprognostic (2.00e-1)" "unprognostic (6.52e-3)" "unprognostic (2.56e-1)" "unprognostic (1.86e-3)" "unprognostic (1.76e-1)" "unprognostic (6.36e-2)" "unprognostic (1.85e-3)" "unprognostic (2.85e-1)" NCAPG "CAP-G, FLJ12450, hCAP-G, YCG1" ENSG00000109805 "Non-SMC condensin I complex subunit G" Q9BPX3 4 17810979-17844865 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 13.1;lymphoid tissue: 14.7" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 33.6;Early primary spermatocytes: 79.6;Erythrocyte progenitors: 137.5;Extravillous trophoblasts: 37.1;Megakaryocyte progenitors: 65.1;Migrating cytotrophoblasts: 26.9;Monocyte progenitors: 138.3;Neutrophil progenitors: 63.5" "Cell type enhanced" "Detected in some" "splatter: 6.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Region enhanced" "Detected in single" "white matter: 1.6" "Low region specificity" "Detected in all" HPA039613 Uncertain NA Yes 21000 "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Non-specific - Cell proliferation" 28 "HPA039613: " "unprognostic (1.92e-2)" "unprognostic (2.76e-2)" "unprognostic (1.27e-1)" "unprognostic (9.79e-2)" "unprognostic (1.29e-2)" "unprognostic (9.82e-2)" "unprognostic (1.23e-1)" "unprognostic (3.82e-2)" "unprognostic (7.33e-2)" "potential prognostic unfavorable (6.23e-4)" "potential prognostic unfavorable (1.04e-4)" "unprognostic (1.00e-3)" "validated prognostic unfavorable (8.17e-6)" "validated prognostic unfavorable (7.02e-8)" "validated prognostic unfavorable (2.32e-5)" "validated prognostic unfavorable (3.63e-4)" "unprognostic (1.66e-2)" "unprognostic (3.90e-2)" "unprognostic (2.04e-1)" "unprognostic (4.49e-2)" "potential prognostic unfavorable (7.20e-6)" "unprognostic (5.46e-2)" "unprognostic (4.75e-2)" "unprognostic (5.25e-3)" "unprognostic (2.44e-1)" "unprognostic (5.56e-2)" "unprognostic (5.24e-2)" "unprognostic (1.38e-1)" "unprognostic (1.73e-1)" NCAPG2 "CAP-G2, FLJ20311, hCAP-G2, LUZP5, MTB" ENSG00000146918 "Non-SMC condensin II complex subunit G2" Q86XI2 7 158631169-158704804 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 23.0;lymphoid tissue: 26.0" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 71.0;Endometrial luminal cells: 65.7;Erythrocyte progenitors: 156.6;Megakaryocyte progenitors: 98.9;Monocyte progenitors: 197.4;Neutrophil progenitors: 127.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026631, HPA049637" Approved Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 39: Non-specific - Transcription" "Cluster 27: Non-specific - Cell proliferation" 8 Nucleoplasm "Nuclear speckles" "HPA026631: , HPA049637: " "unprognostic (1.05e-1)" "unprognostic (3.64e-2)" "unprognostic (1.86e-2)" "unprognostic (2.32e-1)" "unprognostic (3.79e-1)" "unprognostic (1.02e-1)" "unprognostic (1.32e-1)" "unprognostic (2.67e-2)" "unprognostic (2.06e-3)" "potential prognostic unfavorable (4.65e-7)" "unprognostic (1.15e-3)" "potential prognostic unfavorable (3.67e-4)" "unprognostic (1.37e-3)" "validated prognostic unfavorable (1.60e-5)" "validated prognostic unfavorable (6.71e-6)" "validated prognostic unfavorable (1.55e-4)" "validated prognostic unfavorable (6.53e-4)" "unprognostic (2.49e-1)" "unprognostic (3.29e-1)" "unprognostic (6.29e-2)" "unprognostic (2.30e-1)" "unprognostic (1.10e-3)" "unprognostic (2.46e-2)" "unprognostic (8.73e-2)" "unprognostic (2.61e-2)" "unprognostic (7.12e-2)" "unprognostic (1.25e-2)" "unprognostic (4.65e-2)" "unprognostic (2.52e-1)" "unprognostic (1.40e-2)" "unprognostic (7.25e-2)" NCAPH "BRRN1, CAP-H, hCAP-H" ENSG00000121152 "Non-SMC condensin I complex subunit H" Q15003 2 96335766-96377091 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 33.3;intestine: 8.7;lymphoid tissue: 34.8;testis: 33.1" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 33.0;Early primary spermatocytes: 71.5;Erythrocyte progenitors: 96.5;Late primary spermatocytes: 102.8;Megakaryocyte progenitors: 59.8;Monocyte progenitors: 89.9;Neutrophil progenitors: 42.4;Oocytes: 73.7" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 6.2" "Group enriched" "Detected in many" 5 "granulocytes: 3.7;T-cells: 6.2" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Pancreas - Macrophages, Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" "HPA002647, HPA003008" Enhanced Supported Nucleoplasm,Vesicles,Cytosol Yes Yes "Cluster 5: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 9: Non-specific - Receptor signaling" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Non-specific - Cell proliferation" 165 Cytosol "Nucleoplasm, Vesicles" "HPA002647: , HPA003008: " "unprognostic (2.89e-2)" "unprognostic (4.30e-2)" "unprognostic (1.05e-1)" "unprognostic (1.20e-1)" "unprognostic (1.63e-1)" "unprognostic (6.92e-2)" "unprognostic (2.43e-1)" "unprognostic (4.53e-3)" "unprognostic (8.65e-2)" "potential prognostic unfavorable (2.27e-5)" "potential prognostic unfavorable (4.32e-8)" "unprognostic (1.92e-3)" "potential prognostic unfavorable (3.98e-9)" "validated prognostic unfavorable (4.18e-6)" "validated prognostic unfavorable (3.91e-7)" "potential prognostic unfavorable (8.60e-5)" "unprognostic (1.13e-3)" "unprognostic (4.25e-2)" "unprognostic (8.59e-3)" "unprognostic (1.04e-1)" "unprognostic (1.94e-2)" "potential prognostic unfavorable (2.38e-4)" "unprognostic (3.67e-3)" "unprognostic (2.92e-1)" "unprognostic (1.72e-1)" "unprognostic (7.19e-2)" "unprognostic (1.73e-2)" "unprognostic (2.61e-2)" "unprognostic (1.88e-1)" "unprognostic (1.19e-1)" "unprognostic (1.35e-1)" NCAPH2 "384D8-2, CAP-H2, hCAP-H2" ENSG00000025770 "Non-SMC condensin II complex subunit H2" Q6IBW4 22 50508224-50524780 "Essential proteins, Predicted intracellular proteins" "DNA condensation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 67.2;Late spermatids: 189.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067932, HPA069056" Enhanced Supported "Nucleoplasm,Cell Junctions,Cytokinetic bridge" Yes No "Cluster 42: Non-specific - Vesicular transport" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 27: Non-specific - Cell proliferation" 15 Nucleoplasm "Cell Junctions, Cytokinetic bridge" "HPA067932: , HPA069056: " "unprognostic (1.93e-1)" "unprognostic (3.48e-1)" "unprognostic (8.66e-3)" "potential prognostic favorable (3.72e-4)" "unprognostic (2.95e-2)" "unprognostic (1.34e-1)" "unprognostic (1.06e-1)" "unprognostic (2.42e-2)" "unprognostic (5.70e-3)" "unprognostic (9.13e-2)" "unprognostic (6.43e-2)" "unprognostic (1.95e-1)" "potential prognostic favorable (8.23e-4)" "validated prognostic unfavorable (3.67e-4)" "validated prognostic unfavorable (1.72e-4)" "unprognostic (1.21e-1)" "unprognostic (3.00e-2)" "unprognostic (1.33e-2)" "unprognostic (1.35e-1)" "unprognostic (5.54e-2)" "unprognostic (2.53e-2)" "unprognostic (3.42e-2)" "unprognostic (1.18e-2)" "unprognostic (8.08e-3)" "unprognostic (3.01e-1)" "unprognostic (8.02e-3)" "unprognostic (1.25e-1)" "unprognostic (5.58e-2)" "unprognostic (5.15e-2)" "unprognostic (2.44e-2)" "unprognostic (9.41e-2)" NCBP1 "CBP80, NCBP, Sto1" ENSG00000136937 "Nuclear cap binding protein subunit 1" Q09161 9 97633668-97673748 "Essential proteins, Predicted intracellular proteins, Transporters" "mRNA capping, mRNA processing, mRNA splicing, mRNA transport, Nonsense-mediated mRNA decay, RNA-mediated gene silencing, Translation regulation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 202.7;Epicardial cells: 177.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042411, HPA049031" Enhanced Supported Nucleoplasm,Cytosol NA NA 11000 "Cluster 33: Non-specific - ATP binding" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 2: Neurons - Nucleosome" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 120 Cytosol Nucleoplasm "HPA042411: , HPA049031: " "unprognostic (3.72e-1)" "unprognostic (4.70e-2)" "unprognostic (8.34e-3)" "unprognostic (6.19e-2)" "unprognostic (9.09e-2)" "unprognostic (2.36e-1)" "unprognostic (1.09e-1)" "unprognostic (4.67e-2)" "unprognostic (1.15e-1)" "unprognostic (8.23e-3)" "potential prognostic favorable (1.46e-4)" "unprognostic (7.20e-3)" "unprognostic (1.50e-1)" "unprognostic (4.83e-3)" "unprognostic (4.73e-2)" "unprognostic (1.65e-3)" "unprognostic (6.76e-2)" "unprognostic (1.05e-1)" "unprognostic (1.10e-1)" "unprognostic (7.31e-2)" "unprognostic (1.84e-1)" "unprognostic (8.22e-2)" "unprognostic (7.31e-2)" "potential prognostic unfavorable (1.21e-5)" "unprognostic (1.32e-3)" "unprognostic (8.37e-2)" "unprognostic (1.12e-1)" "unprognostic (4.09e-1)" "unprognostic (1.42e-2)" "unprognostic (1.96e-1)" "unprognostic (1.11e-3)" NCBP2 "Cbc2, CBP20, NIP1" ENSG00000114503 "Nuclear cap binding protein subunit 2" P52298 3 196935402-196942594 "Essential proteins, Predicted intracellular proteins, Transporters" "mRNA processing, mRNA splicing, mRNA transport, Nonsense-mediated mRNA decay, RNA-mediated gene silencing, Translation regulation, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044850, HPA062483" Supported Supported "Nucleoplasm,Basal body,Cytosol" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 36: Brain & Liver - Signaling" "Cluster 39: Astrocytes - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 17: Non-specific - RNA processing" 33 Nucleoplasm "Basal body, Cytosol" "HPA044850: , HPA062483: " "unprognostic (2.51e-1)" "potential prognostic unfavorable (2.18e-4)" "unprognostic (1.39e-1)" "unprognostic (9.06e-2)" "unprognostic (1.60e-2)" "unprognostic (1.44e-1)" "unprognostic (1.03e-1)" "unprognostic (5.25e-2)" "unprognostic (2.72e-2)" "potential prognostic unfavorable (8.44e-4)" "unprognostic (4.82e-2)" "unprognostic (8.94e-2)" "unprognostic (1.18e-3)" "validated prognostic unfavorable (1.28e-7)" "validated prognostic unfavorable (2.75e-4)" "unprognostic (1.11e-3)" "unprognostic (1.80e-3)" "unprognostic (4.62e-2)" "unprognostic (2.89e-2)" "unprognostic (3.55e-1)" "unprognostic (2.33e-2)" "potential prognostic unfavorable (6.44e-5)" "unprognostic (3.42e-2)" "potential prognostic unfavorable (4.06e-4)" "unprognostic (1.92e-1)" "unprognostic (2.69e-2)" "unprognostic (1.04e-1)" "unprognostic (1.81e-1)" "unprognostic (2.04e-1)" "unprognostic (2.07e-2)" "unprognostic (7.83e-2)" NCBP2AS2 "HIAR, KRASIM, NCBP2-AS2" ENSG00000270170 "NCBP2 antisense 2 (head to head)" Q69YL0 3 196942674-196943543 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 113.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in some" "basal ganglia: 2.6" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 52: Non-specific - Cellular respiration" "Cluster 14: Neurons - Synaptic function" "Cluster 63: Non-specific - Protein processing" "Cluster 97: Non-specific - Cellular respiration" 3 "unprognostic (9.45e-2)" "unprognostic (4.57e-2)" "unprognostic (4.94e-3)" "unprognostic (2.28e-2)" "potential prognostic favorable (1.16e-7)" "unprognostic (3.87e-2)" "unprognostic (3.83e-2)" "unprognostic (1.96e-1)" "unprognostic (1.06e-1)" "unprognostic (5.17e-2)" "unprognostic (1.27e-1)" "unprognostic (9.37e-3)" "potential prognostic unfavorable (7.04e-5)" "unprognostic (7.30e-2)" "unprognostic (2.09e-3)" "unprognostic (3.16e-2)" "potential prognostic favorable (9.51e-5)" "unprognostic (1.46e-1)" "unprognostic (2.58e-1)" "unprognostic (7.71e-3)" "unprognostic (1.53e-2)" "unprognostic (3.67e-2)" "unprognostic (1.70e-1)" "unprognostic (1.56e-2)" "unprognostic (1.45e-1)" "unprognostic (2.39e-2)" "unprognostic (2.63e-1)" NCBP2L ENSG00000170935 "Nuclear cap binding protein subunit 2 like" A6PVI3 X 107774899-107795829 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "adrenal gland: 1.0" "Cell type enhanced" "Detected in some" "Adipocytes: 5.2;Cardiomyocytes: 9.0;Early spermatids: 22.7;Epicardial cells: 40.9;Late primary spermatocytes: 45.3;Platelets: 17.0" "Cell type enhanced" "Detected in some" "amygdala excitatory: 2.2;upper-layer intratelencephalic: 3.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 78 "basophil: 8.2" "Lineage enriched" "Detected in single" 78 "granulocytes: 8.2" "Not detected" "Not detected" "Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" HPA010664 Uncertain NA NA "Cluster 75: Ovary - Mixed function" "Cluster 34: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" "HPA010664: " NCBP3 "C17orf85, ELG, HSA277841" ENSG00000074356 "Nuclear cap binding subunit 3" Q53F19 17 3802158-3846246 "Predicted intracellular proteins" "Antiviral defense, mRNA capping, mRNA processing, mRNA transport, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008959, HPA013195" Supported Approved "Nuclear speckles" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 67: Testis - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 42: Non-specific - Unknown function" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 39 "Nuclear speckles" "HPA008959: , HPA013195: " "unprognostic (1.51e-1)" "unprognostic (1.06e-1)" "unprognostic (2.22e-1)" "unprognostic (1.94e-1)" "unprognostic (3.42e-1)" "unprognostic (3.06e-1)" "unprognostic (1.86e-3)" "unprognostic (2.29e-2)" "unprognostic (1.17e-2)" "unprognostic (5.43e-2)" "unprognostic (5.55e-3)" "potential prognostic favorable (4.49e-4)" "unprognostic (9.30e-3)" "unprognostic (9.52e-2)" "unprognostic (8.62e-2)" "unprognostic (2.75e-1)" "unprognostic (2.64e-1)" "unprognostic (3.33e-1)" "unprognostic (1.67e-1)" "unprognostic (3.96e-2)" "unprognostic (8.90e-3)" "potential prognostic unfavorable (6.55e-4)" "unprognostic (2.49e-3)" "unprognostic (2.68e-2)" "unprognostic (7.13e-3)" "unprognostic (1.08e-1)" "unprognostic (2.68e-1)" "unprognostic (1.03e-2)" "unprognostic (1.07e-1)" NCCRP1 "FBXO50, LOC342897, NCCRP-1" ENSG00000188505 "NCCRP1, F-box associated domain containing" Q6ZVX7 19 39196964-39201884 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "cervix: 144.0;esophagus: 439.6;lymphoid tissue: 117.1;skin 1: 261.1;vagina: 171.2" "Cell type enriched" "Detected in some" 29 "Esophageal apical cells: 6312.9" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Bladder Urothelial Carcinoma (TCGA): 72.7;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 81.4;Head and Neck Squamous Cell Carcinoma (TCGA): 66.5;Skin Cutaneous Melanoma (TCGA): 50.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.1" "Cancer enhanced" "Detected in many" "cervical cancer: 20.9" "Kidney - Intercalated cells, Prostate - Urothelial cells, Skin - Keratinocyte (granular)" "Region enhanced" "Detected in single" "olfactory bulb: 1.6" "Low region specificity" "Detected in many" "HPA052812, HPA077239" Approved Supported Cytosol NA NA 890000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 37: Neurons - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 84: Apical squamous epithelium - Cornification" 30 Cytosol "HPA052812: , HPA077239: " "unprognostic (2.42e-1)" "unprognostic (1.85e-2)" "unprognostic (4.69e-2)" "unprognostic (2.02e-3)" "unprognostic (1.43e-2)" "unprognostic (1.78e-2)" "unprognostic (2.04e-1)" "unprognostic (1.51e-3)" "unprognostic (5.10e-3)" "unprognostic (2.12e-1)" "unprognostic (1.03e-1)" "unprognostic (4.65e-2)" "unprognostic (8.86e-3)" "unprognostic (3.83e-3)" "unprognostic (2.85e-2)" "unprognostic (1.73e-2)" "unprognostic (1.40e-1)" "unprognostic (3.55e-2)" "unprognostic (3.33e-1)" "unprognostic (9.62e-2)" "unprognostic (7.78e-2)" "unprognostic (2.78e-1)" "unprognostic (2.43e-3)" NCDN "NCDN-1, NCDN-2" ENSG00000020129 Neurochondrin Q9UBB6 1 35557473-35567274 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 25 "brain: 912.9" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 31.9;Brain excitatory neurons: 63.8;Brain inhibitory neurons: 88.5;Other brain neurons: 56.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023676 Enhanced Supported Supported Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 35: Neurons - Synaptic function & neurogenesis" 28 Cytosol "HPA023676: " "unprognostic (1.12e-1)" "unprognostic (4.22e-2)" "unprognostic (2.29e-1)" "unprognostic (3.18e-3)" "unprognostic (1.46e-1)" "unprognostic (2.63e-1)" "unprognostic (5.59e-2)" "unprognostic (1.56e-1)" "unprognostic (5.55e-2)" "unprognostic (2.88e-2)" "unprognostic (7.50e-3)" "unprognostic (2.88e-1)" "potential prognostic favorable (2.56e-4)" "potential prognostic unfavorable (2.56e-6)" "unprognostic (1.25e-2)" "unprognostic (1.28e-1)" "unprognostic (3.41e-1)" "unprognostic (1.20e-1)" "unprognostic (3.53e-2)" "unprognostic (2.54e-2)" "unprognostic (2.18e-1)" "unprognostic (1.68e-2)" "unprognostic (5.69e-3)" "unprognostic (1.19e-2)" "unprognostic (2.70e-1)" "unprognostic (8.07e-2)" "unprognostic (1.20e-1)" "unprognostic (8.24e-2)" "unprognostic (1.52e-1)" "unprognostic (9.29e-2)" "unprognostic (3.38e-1)" NCEH1 "AADACL1, KIAA1363, NCEH" ENSG00000144959 "Neutral cholesterol ester hydrolase 1" Q6PIU2 3 172630249-172711218 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 306.9;Endometrial glandular cells: 366.5;Pancreatic duct cells: 761.4;Urothelial cells: 570.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026888, HPA043873" Enhanced Approved "Endoplasmic reticulum" No No "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 36: Brain & Liver - Signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 72: Neuronal - Signal transduction" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 4 "Endoplasmic reticulum" "HPA026888: , HPA043873: " "unprognostic (8.66e-2)" "unprognostic (7.18e-2)" "unprognostic (5.31e-2)" "unprognostic (2.15e-2)" "unprognostic (9.16e-2)" "unprognostic (1.78e-1)" "unprognostic (2.67e-2)" "unprognostic (1.57e-3)" "unprognostic (2.24e-2)" "potential prognostic unfavorable (7.05e-4)" "potential prognostic favorable (7.38e-6)" "unprognostic (2.12e-1)" "unprognostic (3.96e-2)" "unprognostic (4.88e-2)" "unprognostic (3.48e-1)" "potential prognostic unfavorable (6.29e-4)" "unprognostic (2.16e-2)" "unprognostic (1.36e-1)" "unprognostic (1.58e-1)" "unprognostic (9.40e-3)" "potential prognostic unfavorable (6.23e-4)" "potential prognostic unfavorable (2.42e-4)" "unprognostic (2.32e-1)" "unprognostic (1.28e-1)" "unprognostic (1.48e-1)" "unprognostic (2.12e-1)" "unprognostic (6.94e-2)" "unprognostic (1.62e-1)" "unprognostic (5.17e-2)" "unprognostic (6.53e-3)" "unprognostic (2.84e-1)" NCF1 "NCF1A, NOXO2, p47phox, SH3PXD1A" ENSG00000158517 "Neutrophil cytosolic factor 1" P14598 7 74774011-74789315 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Chronic granulomatous disease, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 84.4;lymphoid tissue: 97.8" "Group enriched" "Detected in some" 5 "Neutrophil progenitors: 68.7;Neutrophils: 234.9" "Group enriched" "Detected in some" 25 "central nervous system macrophage: 26.3;leukocyte: 17.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 1230.4;classical monocyte: 721.2;eosinophil: 1565.9;neutrophil: 2260.8" "Group enriched" "Detected in all" 5 "granulocytes: 2260.8;monocytes: 721.2" "Group enriched" "Detected in some" 4 "Leukemia: 38.4;lymphoma: 101.8" "Adrenal gland - Macrophages, Kidney - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004524, HPA047836, HPA052095" Enhanced NA NA 55000 "Cluster 20: Non-specific - DNA binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 25: Non-specific - Transcription" "Cluster 55: Lymphoma - Immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 37 "CAB004524: , HPA047836: , HPA052095: " "unprognostic (1.21e-2)" "unprognostic (8.37e-2)" "unprognostic (5.31e-2)" "unprognostic (1.01e-2)" "unprognostic (8.05e-2)" "unprognostic (2.49e-1)" "unprognostic (2.67e-2)" "unprognostic (1.02e-1)" "unprognostic (8.07e-3)" "unprognostic (3.24e-1)" "unprognostic (1.07e-1)" "unprognostic (3.96e-1)" "unprognostic (2.34e-2)" "unprognostic (2.73e-2)" "unprognostic (1.16e-1)" "unprognostic (5.14e-2)" "unprognostic (2.50e-1)" "unprognostic (1.97e-1)" "unprognostic (6.82e-2)" "unprognostic (8.42e-2)" "unprognostic (3.87e-2)" "unprognostic (1.98e-2)" "unprognostic (8.63e-3)" "unprognostic (1.72e-1)" "unprognostic (4.03e-2)" "unprognostic (9.70e-2)" "unprognostic (3.50e-3)" "unprognostic (3.01e-1)" "unprognostic (5.67e-2)" "unprognostic (3.16e-2)" "unprognostic (6.90e-2)" NCF2 "NOXA2, p67phox" ENSG00000116701 "Neutrophil cytosolic factor 2" P19878 1 183554461-183590905 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Chronic granulomatous disease, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 119.1;lung: 61.2;lymphoid tissue: 73.9" "Cell type enriched" "Detected in many" 4 "Neutrophils: 1818.7" "Group enriched" "Detected in some" 8 "central nervous system macrophage: 40.2;leukocyte: 22.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 1253.7" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "lymphoma: 37.9" "Adipose subcutaneous - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Kidney - Macrophages, Liver - Neutrophils, Lung - Neutrophils_2, Minor Salivary Gland - Macrophages, Prostate - Macrophages, Spleen - Neutrophils_2, Testis - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002327, HPA006040, CAB022160" Enhanced Supported Cytosol NA NA 4800 "Cluster 7: Non-specific - Innate immune response" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 55: Lymphoma - Immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 22 Cytosol "CAB022160: , HPA002327: , HPA006040: " "unprognostic (1.17e-1)" "unprognostic (2.93e-2)" "unprognostic (3.71e-2)" "unprognostic (2.68e-1)" "unprognostic (2.64e-1)" "unprognostic (9.01e-2)" "unprognostic (3.24e-3)" "unprognostic (4.18e-2)" "unprognostic (1.73e-3)" "unprognostic (9.14e-3)" "unprognostic (3.77e-2)" "unprognostic (1.37e-1)" "unprognostic (1.20e-1)" "potential prognostic unfavorable (3.03e-5)" "unprognostic (1.83e-1)" "unprognostic (4.55e-1)" "potential prognostic unfavorable (5.83e-4)" "unprognostic (1.68e-2)" "unprognostic (4.46e-2)" "unprognostic (1.80e-1)" "unprognostic (6.32e-2)" "unprognostic (7.04e-2)" "unprognostic (7.82e-2)" "unprognostic (2.07e-1)" "potential prognostic unfavorable (3.22e-4)" "unprognostic (1.01e-3)" "unprognostic (3.17e-1)" "unprognostic (5.77e-2)" "unprognostic (9.50e-3)" "unprognostic (1.18e-1)" "unprognostic (2.80e-1)" NCF4 "p40phox, SH3PXD4" ENSG00000100365 "Neutrophil cytosolic factor 4" Q15080 22 36860988-36878017 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Chronic granulomatous disease, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 170.3;lymphoid tissue: 156.4" "Group enriched" "Detected in many" 4 "Hofbauer cells: 352.2;Neutrophil progenitors: 226.8;Neutrophils: 586.3" "Group enriched" "Detected in some" 17 "central nervous system macrophage: 34.0;leukocyte: 8.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 658.7;eosinophil: 751.6;neutrophil: 1240.1" "Lineage enriched" "Detected in all" 7 "granulocytes: 1240.1" "Group enriched" "Detected in some" 7 "Leukemia: 121.1;lymphoma: 53.0" "Breast - Macrophages, Lung - Neutrophils_2, Skeletal muscle - Macrophages, Spleen - Neutrophils_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB010146, HPA036156, HPA057975" Enhanced Enhanced Cytosol NA NA 11000 "Cluster 21: Neutrophils - Unknown function" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 49: HMC-1 - Innate immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 8 Cytosol "CAB010146: , HPA036156: , HPA057975: " "unprognostic (3.90e-2)" "unprognostic (2.76e-2)" "unprognostic (7.36e-3)" "unprognostic (1.26e-1)" "unprognostic (5.89e-2)" "unprognostic (1.31e-1)" "unprognostic (6.21e-2)" "unprognostic (1.28e-1)" "unprognostic (9.13e-3)" "unprognostic (2.08e-1)" "potential prognostic unfavorable (4.90e-5)" "unprognostic (3.96e-2)" "unprognostic (6.56e-2)" "unprognostic (2.28e-2)" "unprognostic (4.98e-2)" "unprognostic (1.02e-2)" "unprognostic (7.86e-2)" "unprognostic (1.28e-1)" "unprognostic (2.20e-1)" "unprognostic (1.74e-1)" "unprognostic (8.54e-2)" "unprognostic (1.12e-2)" "unprognostic (8.52e-2)" "unprognostic (9.00e-2)" "unprognostic (1.26e-1)" "unprognostic (5.04e-2)" "unprognostic (3.50e-3)" "unprognostic (3.66e-1)" "unprognostic (2.07e-3)" "unprognostic (1.50e-1)" "unprognostic (4.17e-1)" NCK1 "NCK, NCKalpha" ENSG00000158092 "NCK adaptor protein 1" P16333 3 136862208-136951606 "Predicted intracellular proteins" "Translation regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005063, HPA030766" Supported Approved "Plasma membrane,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 63: Non-specific - Protein processing" "Cluster 7: Non-specific - Transcription" 136 "Plasma membrane, Cytosol" "CAB005063: , HPA030766: " "unprognostic (2.30e-1)" "unprognostic (9.09e-2)" "unprognostic (9.05e-2)" "unprognostic (2.12e-2)" "unprognostic (3.59e-1)" "unprognostic (1.92e-2)" "unprognostic (5.76e-2)" "unprognostic (4.27e-1)" "unprognostic (2.27e-3)" "potential prognostic unfavorable (2.45e-6)" "potential prognostic favorable (6.99e-5)" "unprognostic (8.64e-3)" "unprognostic (3.00e-3)" "unprognostic (1.69e-3)" "unprognostic (1.66e-1)" "unprognostic (1.07e-2)" "unprognostic (1.90e-1)" "unprognostic (2.53e-1)" "unprognostic (1.14e-1)" "unprognostic (3.93e-1)" "unprognostic (1.69e-2)" "potential prognostic unfavorable (2.94e-4)" "unprognostic (1.01e-2)" "unprognostic (1.41e-1)" "unprognostic (3.79e-2)" "unprognostic (2.50e-1)" "unprognostic (3.51e-3)" "unprognostic (1.31e-1)" "unprognostic (1.31e-1)" "unprognostic (1.57e-1)" "unprognostic (5.19e-1)" NCK2 NCKbeta ENSG00000071051 "NCK adaptor protein 2" O43639 2 105744912-105894274 "Plasma proteins, Predicted intracellular proteins" "Translation regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 356.3;Microglia: 297.5;Platelets: 915.4" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 361.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Skin - Outer root sheath cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016116, HPA031004" Approved NA NA 260000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 24: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 9: T-cells - Adaptive immunity: Regulation" 189 "CAB016116: , HPA031004: " "unprognostic (1.62e-1)" "unprognostic (1.72e-1)" "unprognostic (5.65e-2)" "unprognostic (8.36e-3)" "unprognostic (5.89e-2)" "unprognostic (1.83e-1)" "unprognostic (2.06e-1)" "unprognostic (2.13e-2)" "unprognostic (3.46e-2)" "unprognostic (2.73e-3)" "validated prognostic favorable (6.22e-5)" "validated prognostic favorable (3.34e-5)" "unprognostic (1.36e-2)" "unprognostic (2.06e-2)" "unprognostic (2.12e-1)" "unprognostic (2.18e-3)" "unprognostic (3.65e-3)" "unprognostic (9.77e-2)" "unprognostic (7.10e-2)" "unprognostic (6.92e-2)" "unprognostic (1.84e-1)" "unprognostic (1.40e-1)" "unprognostic (1.65e-1)" "unprognostic (2.21e-2)" "unprognostic (3.68e-1)" "unprognostic (1.81e-2)" "unprognostic (1.61e-2)" "unprognostic (8.82e-2)" "unprognostic (2.73e-2)" "unprognostic (8.08e-2)" "unprognostic (2.22e-1)" NCKAP1 "HEM2, Nap1, NAP125" ENSG00000061676 "NCK associated protein 1" Q9Y2A7 2 182909115-183038858 "Predicted membrane proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020449 Enhanced Approved Cytosol NA NA 15000 "Cluster 69: Parathyroid gland - Mixed function" "Cluster 14: Neurons - Synaptic function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 94 Cytosol "HPA020449: " "unprognostic (2.45e-1)" "unprognostic (4.77e-3)" "unprognostic (3.02e-1)" "unprognostic (7.16e-3)" "unprognostic (7.70e-3)" "unprognostic (1.20e-1)" "unprognostic (2.46e-2)" "unprognostic (7.51e-2)" "unprognostic (2.31e-1)" "unprognostic (1.05e-1)" "validated prognostic favorable (7.02e-7)" "validated prognostic favorable (6.09e-4)" "unprognostic (5.76e-2)" "unprognostic (2.91e-3)" "unprognostic (1.14e-3)" "unprognostic (1.28e-2)" "unprognostic (3.13e-2)" "unprognostic (3.21e-2)" "unprognostic (2.32e-2)" "unprognostic (2.15e-1)" "unprognostic (1.39e-2)" "unprognostic (1.58e-3)" "unprognostic (4.65e-2)" "unprognostic (3.91e-2)" "unprognostic (7.01e-3)" "unprognostic (7.17e-2)" "unprognostic (1.71e-1)" "unprognostic (8.57e-2)" "unprognostic (3.61e-1)" "unprognostic (2.04e-1)" "unprognostic (7.17e-2)" NCKAP1L HEM1 ENSG00000123338 "NCK associated protein 1 like" P55160 12 54497752-54548243 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 43.0" "Cell type enhanced" "Detected in many" "B-cells: 112.0;cDC: 143.8;Hematopoietic stem cells: 111.1;Hofbauer cells: 199.5;Kupffer cells: 260.3;Macrophages: 193.2;Microglia: 262.5;Monocyte progenitors: 162.5;monocytes: 227.4;Neutrophil progenitors: 263.0;Neutrophils: 227.5;NK-cells: 105.4;pDCs: 125.9;Smooth muscle cells: 99.0;T-cells: 86.7;Thymocytes: 90.6" "Group enriched" "Detected in many" 86 "central nervous system macrophage: 334.1;leukocyte: 155.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Bone cancer: 54.5;Leukemia: 63.4;lymphoma: 53.7" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Heart muscle - Macrophages, Liver - Kupffer cells, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Skeletal muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039490, HPA040772" Approved Supported "Plasma membrane,Cytosol" NA NA 22000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" Cytosol "Plasma membrane" "HPA039490: , HPA040772: " "unprognostic (2.50e-2)" "unprognostic (5.44e-3)" "unprognostic (1.32e-1)" "unprognostic (1.06e-2)" "unprognostic (4.53e-2)" "unprognostic (2.32e-1)" "unprognostic (1.10e-2)" "unprognostic (1.07e-1)" "unprognostic (5.83e-3)" "unprognostic (2.90e-1)" "unprognostic (4.28e-2)" "unprognostic (2.64e-1)" "unprognostic (1.80e-1)" "unprognostic (5.04e-2)" "unprognostic (7.94e-2)" "unprognostic (7.68e-3)" "unprognostic (1.70e-1)" "unprognostic (8.60e-2)" "unprognostic (2.15e-1)" "unprognostic (2.74e-1)" "unprognostic (2.57e-1)" "unprognostic (1.13e-1)" "unprognostic (2.45e-2)" "unprognostic (2.42e-1)" "unprognostic (2.02e-1)" "unprognostic (2.95e-2)" "unprognostic (2.27e-2)" "unprognostic (3.65e-1)" "unprognostic (2.75e-2)" "unprognostic (8.92e-2)" "unprognostic (3.62e-1)" NCKAP5 "ERIH1, ERIH2, NAP5" ENSG00000176771 "NCK associated protein 5" O14513 2 132671788-133568463 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 10.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 2153.5;Bergmann glia: 1712.5;Müller glia: 823.4;Oligodendrocyte progenitor cells: 986.2;Oligodendrocytes: 2237.0;Proximal tubule cells: 820.9;Retinal bipolar cells: 1323.5;Retinal pigment epithelial cells: 1018.8;Salivary ionocytes: 1915.5" "Cell type enhanced" "Detected in all" "Bergmann glia: 1724.0;committed oligodendrocyte precursor: 1682.3;oligodendrocyte: 2771.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "thyroid cancer: 9.5" "Adipose subcutaneous - Endothelial cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Alveolar cells type 1, Skeletal muscle - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034639, HPA044859" Uncertain Approved "Nucleoli,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 6: Non-specific - Immune response" "Cluster 65: Non-specific - Unknown function" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 4 Nucleoli "Golgi apparatus, Plasma membrane, Cytosol" "HPA034639: , HPA044859: " "unprognostic (1.79e-1)" "unprognostic (2.90e-1)" "unprognostic (2.18e-1)" "unprognostic (3.75e-2)" "unprognostic (1.12e-3)" "unprognostic (8.74e-2)" "unprognostic (1.26e-2)" "unprognostic (2.97e-1)" "unprognostic (7.37e-2)" "potential prognostic favorable (3.45e-9)" "unprognostic (3.44e-2)" "unprognostic (1.81e-3)" "unprognostic (5.38e-3)" "unprognostic (1.92e-1)" "unprognostic (5.49e-2)" "unprognostic (7.30e-2)" "unprognostic (4.02e-3)" "unprognostic (6.07e-2)" "unprognostic (2.77e-2)" "unprognostic (4.18e-2)" "unprognostic (3.22e-1)" NCKAP5L KIAA1602 ENSG00000167566 "NCK associated protein 5 like" Q9HCH0 12 49791146-49828750 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Leydig cells: 93.7;Peritubular myoid cells: 126.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041034 Approved NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 20: Non-specific - Transcription regulation" 12 "HPA041034: " "unprognostic (1.40e-1)" "unprognostic (5.56e-2)" "unprognostic (1.72e-1)" "potential prognostic unfavorable (2.16e-4)" "unprognostic (7.29e-3)" "unprognostic (1.01e-1)" "unprognostic (2.93e-1)" "unprognostic (1.93e-2)" "unprognostic (4.64e-2)" "unprognostic (9.92e-2)" "potential prognostic unfavorable (4.40e-7)" "unprognostic (1.16e-2)" "unprognostic (3.65e-1)" "potential prognostic unfavorable (7.70e-6)" "unprognostic (3.77e-3)" "unprognostic (2.09e-3)" "unprognostic (3.62e-2)" "unprognostic (2.16e-1)" "unprognostic (4.40e-2)" "unprognostic (3.08e-2)" "unprognostic (1.18e-1)" "unprognostic (4.10e-3)" "unprognostic (3.46e-2)" "unprognostic (1.13e-1)" "unprognostic (7.76e-2)" "potential prognostic favorable (5.59e-4)" "unprognostic (2.27e-1)" "unprognostic (2.76e-2)" "unprognostic (4.27e-1)" "unprognostic (3.15e-3)" "unprognostic (1.05e-1)" NCKIPSD "AF3P21, DIP1, ORF1, SPIN90, WASLBP, WISH" ENSG00000213672 "NCK interacting protein with SH3 domain" Q9NZQ3 3 48673844-48686364 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 114.5" "Cell type enhanced" "Detected in many" "Megakaryocytes: 68.0;Oocytes: 69.1;Peritubular myoid cells: 45.9;Platelets: 70.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064985 Supported "Nucleoplasm,Plasma membrane" NA NA 33000 "Cluster 13: Non-specific - Mitochondria" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 47: Platelets - Hemostasis" 36 Nucleoplasm "Plasma membrane" "HPA064985: " "unprognostic (9.70e-2)" "unprognostic (1.09e-1)" "unprognostic (2.15e-1)" "unprognostic (1.30e-1)" "unprognostic (1.69e-1)" "unprognostic (2.13e-1)" "unprognostic (1.48e-1)" "unprognostic (2.93e-1)" "unprognostic (2.43e-1)" "unprognostic (4.30e-3)" "validated prognostic favorable (8.93e-5)" "validated prognostic favorable (4.23e-4)" "potential prognostic favorable (2.28e-5)" "potential prognostic unfavorable (4.98e-4)" "unprognostic (1.27e-1)" "unprognostic (4.55e-3)" "potential prognostic unfavorable (3.10e-4)" "unprognostic (5.88e-2)" "unprognostic (6.51e-3)" "unprognostic (2.07e-1)" "unprognostic (2.68e-1)" "unprognostic (5.68e-2)" "unprognostic (2.09e-2)" "unprognostic (1.78e-1)" "unprognostic (1.66e-1)" "unprognostic (2.44e-1)" "unprognostic (1.65e-1)" "unprognostic (8.40e-2)" "unprognostic (4.30e-1)" "unprognostic (2.20e-1)" "unprognostic (1.22e-1)" NCL "C23, Nsr1" ENSG00000115053 Nucleolin P19338 2 231453531-231483641 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 1065.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004210, HPA023981, HPA071110" Supported Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No 1900000 "Cluster 30: Non-specific - DNA binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 17: Non-specific - RNA processing" 300 "Nucleoplasm, Nucleoli, Nucleoli rim" "Mitotic chromosome" "CAB004210: , HPA023981: , HPA071110: " "unprognostic (6.96e-2)" "unprognostic (1.22e-1)" "unprognostic (1.08e-1)" "unprognostic (4.25e-3)" "unprognostic (1.00e-1)" "unprognostic (3.56e-1)" "unprognostic (2.33e-2)" "unprognostic (2.85e-2)" "unprognostic (1.57e-2)" "unprognostic (5.20e-2)" "potential prognostic favorable (6.60e-5)" "unprognostic (4.51e-2)" "unprognostic (5.17e-2)" "validated prognostic unfavorable (2.59e-7)" "validated prognostic unfavorable (3.33e-7)" "potential prognostic unfavorable (5.83e-4)" "unprognostic (1.83e-3)" "unprognostic (4.79e-2)" "unprognostic (1.83e-2)" "unprognostic (1.89e-1)" "unprognostic (2.77e-1)" "unprognostic (1.40e-2)" "unprognostic (1.33e-2)" "unprognostic (7.44e-2)" "unprognostic (5.52e-2)" "unprognostic (2.77e-2)" "unprognostic (3.87e-2)" "unprognostic (4.95e-2)" "unprognostic (3.49e-1)" "unprognostic (1.41e-1)" "unprognostic (2.25e-2)" NCLN "NET59, NICALIN" ENSG00000125912 Nicalin Q969V3 19 3185563-3209575 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006625 Approved Approved "Nucleoplasm,Lipid droplets" NA NA 4200 "Cluster 2: Dendritic cells - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 35 "Lipid droplets" Nucleoplasm "HPA006625: " "unprognostic (7.67e-2)" "unprognostic (7.79e-3)" "unprognostic (1.14e-2)" "unprognostic (7.09e-3)" "unprognostic (5.05e-2)" "unprognostic (2.06e-1)" "unprognostic (1.58e-1)" "unprognostic (3.45e-1)" "unprognostic (3.23e-1)" "unprognostic (2.13e-1)" "potential prognostic unfavorable (3.38e-4)" "unprognostic (3.52e-3)" "unprognostic (3.29e-2)" "validated prognostic unfavorable (1.47e-6)" "validated prognostic unfavorable (4.71e-5)" "unprognostic (3.64e-2)" "unprognostic (3.15e-2)" "unprognostic (2.18e-1)" "unprognostic (1.20e-1)" "unprognostic (5.82e-2)" "unprognostic (1.38e-1)" "unprognostic (1.40e-2)" "unprognostic (1.62e-1)" "unprognostic (6.68e-3)" "unprognostic (5.61e-2)" "unprognostic (3.06e-2)" "unprognostic (5.87e-2)" "potential prognostic favorable (6.21e-4)" "unprognostic (2.59e-1)" "unprognostic (8.43e-3)" "unprognostic (5.51e-3)" NCMAP "C1orf130, FLJ42528, MP11" ENSG00000184454 "Non-compact myelin associated protein" Q5T1S8 1 24556087-24609328 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "gallbladder: 6.9;pancreas: 8.1;salivary gland: 7.3" "Cell type enriched" "Detected in many" 4 "Tuft cells: 645.6" "Cell type enriched" "Detected in some" 15 "central nervous system macrophage: 40.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 2.8" "Liver - Hepatocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Ductal cells, Prostate - Prostate glandular cells, Stomach - Parietal cells" "Low region specificity" "Detected in many" HPA013656 Uncertain NA NA "Cluster 60: Stomach - Digestion" "Cluster 6: Non-specific - Immune response" "Cluster 20: Myeloma - Immune response" "Cluster 95: Tuft cells - Chemosensory signaling" "HPA013656: " "unprognostic (2.04e-2)" "unprognostic (3.72e-2)" "unprognostic (3.27e-2)" "unprognostic (1.86e-1)" "unprognostic (1.05e-1)" "unprognostic (3.87e-2)" "unprognostic (1.71e-1)" "unprognostic (1.11e-1)" "unprognostic (1.19e-1)" "unprognostic (1.52e-2)" "unprognostic (2.00e-2)" "unprognostic (1.74e-2)" "unprognostic (2.96e-1)" "unprognostic (2.59e-1)" "unprognostic (4.60e-2)" "unprognostic (4.69e-1)" "unprognostic (1.60e-1)" "unprognostic (1.33e-1)" "unprognostic (4.31e-1)" "unprognostic (5.47e-2)" "unprognostic (7.19e-2)" "unprognostic (1.69e-2)" NCOA1 "bHLHe74, F-SRC-1, KAT13A, NCoA-1, RIP160, SRC1" ENSG00000084676 "Nuclear receptor coactivator 1" Q15788 2 24491254-24770702 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Acyltransferase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Bergmann glia: 1220.4;Neutrophils: 2074.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019402, HPA070213, HPA070520" Supported Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" No No "Cluster 41: Basophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 59: Leukemia - T-cell receptor" "Cluster 24: Neutrophils - Innate immunity signal integration" 84 "Nucleoplasm, Cytosol" "Vesicles, Plasma membrane" "CAB019402: , HPA070213: , HPA070520: " "unprognostic (1.90e-1)" "unprognostic (2.11e-1)" "unprognostic (5.11e-2)" "unprognostic (3.61e-2)" "unprognostic (1.98e-2)" "unprognostic (3.14e-2)" "unprognostic (8.90e-2)" "unprognostic (9.48e-2)" "unprognostic (2.00e-2)" "unprognostic (5.22e-3)" "potential prognostic favorable (1.39e-6)" "unprognostic (5.70e-3)" "unprognostic (2.35e-1)" "unprognostic (1.73e-2)" "unprognostic (2.01e-1)" "unprognostic (1.20e-1)" "unprognostic (2.79e-1)" "unprognostic (1.58e-1)" "unprognostic (1.73e-1)" "unprognostic (1.69e-1)" "unprognostic (2.88e-1)" "unprognostic (3.34e-2)" "unprognostic (8.23e-2)" "unprognostic (1.97e-1)" "unprognostic (9.24e-2)" "unprognostic (6.04e-2)" "unprognostic (1.15e-1)" "unprognostic (2.63e-2)" "unprognostic (2.90e-1)" "unprognostic (3.12e-2)" "unprognostic (1.52e-2)" NCOA2 "bHLHe75, GRIP1, KAT13C, NCoA-2, TIF2" ENSG00000140396 "Nuclear receptor coactivator 2" Q15596 8 70109782-70403808 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" Activator "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 1361.0;Neutrophils: 1920.1;Sertoli cells: 1563.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060243 Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 40: Non-specific - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 40: Non-specific - Unknown function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 40 "Nucleoplasm, Nuclear bodies" "HPA060243: " "unprognostic (7.82e-2)" "potential prognostic unfavorable (7.41e-4)" "unprognostic (9.92e-2)" "unprognostic (6.39e-2)" "unprognostic (7.80e-2)" "unprognostic (1.61e-2)" "unprognostic (7.50e-3)" "potential prognostic favorable (2.56e-4)" "unprognostic (5.33e-3)" "potential prognostic unfavorable (1.84e-4)" "potential prognostic favorable (8.56e-8)" "unprognostic (1.74e-2)" "unprognostic (1.58e-1)" "unprognostic (9.94e-2)" "unprognostic (2.42e-1)" "unprognostic (1.65e-1)" "unprognostic (1.07e-1)" "unprognostic (9.30e-2)" "unprognostic (9.11e-2)" "unprognostic (1.46e-2)" "unprognostic (5.07e-3)" "unprognostic (2.18e-2)" "unprognostic (1.69e-2)" "unprognostic (2.29e-2)" "unprognostic (1.96e-1)" "unprognostic (2.43e-1)" "unprognostic (7.89e-2)" "unprognostic (2.57e-1)" "unprognostic (2.62e-1)" "unprognostic (8.07e-2)" "unprognostic (5.49e-2)" NCOA3 "ACTR, AIB1, bHLHe42, CAGH16, KAT13B, p/CIP, RAC3, SRC-3, SRC3, TNRC16, TRAM-1" ENSG00000124151 "Nuclear receptor coactivator 3" Q9Y6Q9 20 47501887-47656877 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Acyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "B-cells: 756.0;Endometrial glandular cells: 687.4;Plasma cells: 860.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009800, HPA024210" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 70 Nucleoplasm Cytosol "CAB009800: , HPA024210: " "unprognostic (2.54e-1)" "unprognostic (3.45e-3)" "unprognostic (3.22e-1)" "unprognostic (4.05e-3)" "unprognostic (3.08e-1)" "unprognostic (1.52e-1)" "unprognostic (1.36e-1)" "unprognostic (3.59e-1)" "unprognostic (8.74e-2)" "unprognostic (3.25e-2)" "potential prognostic favorable (6.35e-5)" "unprognostic (1.90e-3)" "unprognostic (1.81e-2)" "unprognostic (5.59e-3)" "unprognostic (7.43e-2)" "unprognostic (7.24e-2)" "unprognostic (2.11e-2)" "unprognostic (1.93e-2)" "unprognostic (8.02e-3)" "unprognostic (4.68e-3)" "potential prognostic unfavorable (1.85e-4)" "unprognostic (3.23e-2)" "potential prognostic unfavorable (1.55e-4)" "unprognostic (1.28e-1)" "unprognostic (3.01e-3)" "unprognostic (1.05e-2)" "unprognostic (2.99e-1)" "unprognostic (2.25e-1)" "unprognostic (5.13e-2)" "unprognostic (6.48e-2)" "unprognostic (3.79e-2)" NCOA4 "ARA70, DKFZp762E1112, ELE1, PTC3, RFG" ENSG00000266412 "Nuclear receptor coactivator 4" Q13772 10 46005088-46030623 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Kupffer cells: 463.3;Megakaryocytes: 463.6;Neutrophils: 364.2;Platelets: 1775.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 252.1;granulocytes: 842.8;monocytes: 363.8" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051260, HPA065208" Uncertain Approved "Nucleoli,Golgi apparatus,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 76: Non-specific - Metabolism" "Cluster 27: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 47: Platelets - Hemostasis" 16 Nucleoli "Golgi apparatus, Cytosol" "HPA051260: , HPA065208: " "unprognostic (4.09e-1)" "unprognostic (1.43e-2)" "unprognostic (3.90e-3)" "unprognostic (1.36e-1)" "unprognostic (5.08e-2)" "unprognostic (1.09e-1)" "unprognostic (1.20e-2)" "unprognostic (1.13e-2)" "unprognostic (1.53e-2)" "potential prognostic favorable (5.08e-13)" "unprognostic (1.01e-2)" "unprognostic (1.11e-1)" "unprognostic (4.61e-1)" "unprognostic (3.97e-2)" "unprognostic (3.45e-2)" "unprognostic (8.81e-2)" "unprognostic (1.55e-1)" "unprognostic (4.06e-2)" "unprognostic (4.53e-2)" "unprognostic (4.64e-2)" "unprognostic (7.68e-2)" "unprognostic (4.07e-1)" "unprognostic (1.09e-1)" "unprognostic (2.70e-1)" "unprognostic (8.09e-2)" "unprognostic (3.25e-2)" "unprognostic (9.12e-2)" "unprognostic (1.86e-1)" NCOA5 "bA465L10.6, CIA" ENSG00000124160 "Nuclear receptor coactivator 5" Q9HCD5 20 46060991-46089962 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050231 Uncertain Supported "Nucleoplasm,Actin filaments" NA NA 8500 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 39: Testis - Nuclear processes" "Cluster 16: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 7: Non-specific - Transcription" 19 "Nucleoplasm, Actin filaments" "HPA050231: " "unprognostic (1.27e-1)" "unprognostic (7.10e-3)" "unprognostic (1.73e-1)" "unprognostic (1.95e-2)" "unprognostic (1.92e-1)" "unprognostic (7.07e-2)" "unprognostic (3.79e-1)" "unprognostic (5.24e-2)" "unprognostic (1.27e-2)" "unprognostic (4.51e-3)" "validated prognostic favorable (1.17e-4)" "validated prognostic favorable (3.11e-4)" "unprognostic (1.92e-1)" "validated prognostic unfavorable (4.51e-6)" "validated prognostic unfavorable (3.35e-4)" "unprognostic (1.15e-1)" "unprognostic (8.17e-2)" "unprognostic (3.13e-2)" "unprognostic (3.27e-3)" "unprognostic (9.94e-2)" "unprognostic (2.12e-1)" "potential prognostic favorable (3.76e-4)" "unprognostic (2.61e-1)" "unprognostic (5.20e-2)" "unprognostic (1.41e-3)" "unprognostic (6.09e-2)" "unprognostic (4.85e-2)" "unprognostic (5.15e-2)" "unprognostic (1.70e-1)" "unprognostic (9.66e-2)" "unprognostic (1.64e-1)" NCOA6 "AIB3, ASC2, KIAA0181, NRC, PRIP, RAP250, TRBP" ENSG00000198646 "Nuclear receptor coactivator 6" Q14686 20 34689097-34825651 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 369.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004198, HPA050211" Supported Supported Nucleoplasm NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 62: Non-specific - Plasma proteins" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 63 Nucleoplasm "HPA004198: , HPA050211: " "unprognostic (8.09e-2)" "unprognostic (7.85e-2)" "unprognostic (3.53e-2)" "unprognostic (5.04e-2)" "unprognostic (2.27e-1)" "unprognostic (4.84e-2)" "unprognostic (2.60e-1)" "unprognostic (1.96e-1)" "unprognostic (1.67e-1)" "unprognostic (4.69e-3)" "potential prognostic favorable (2.08e-5)" "unprognostic (2.67e-2)" "unprognostic (2.98e-1)" "potential prognostic unfavorable (7.25e-4)" "unprognostic (4.67e-2)" "unprognostic (1.37e-2)" "unprognostic (9.06e-2)" "unprognostic (6.59e-2)" "unprognostic (6.16e-2)" "unprognostic (7.00e-2)" "unprognostic (1.08e-1)" "unprognostic (7.64e-3)" "unprognostic (3.87e-3)" "unprognostic (4.72e-2)" "unprognostic (8.40e-3)" "unprognostic (3.35e-2)" "unprognostic (1.85e-1)" "unprognostic (3.33e-1)" "unprognostic (3.87e-1)" "unprognostic (5.16e-2)" "unprognostic (6.33e-2)" NCOA7 "dJ187J11.3, ERAP140, TLDC4" ENSG00000111912 "Nuclear receptor coactivator 7" Q8NI08 6 125781161-125932034 "Predicted intracellular proteins, Transporters" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal basal cells: 1214.6;Salivary ionocytes: 924.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030289, HPA030290, HPA030291, HPA030292" Approved Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus" No No "Cluster 41: Basophils - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 37: Neurons - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 8 "Nucleoplasm, Nuclear bodies" "Golgi apparatus" "HPA030289: , HPA030290: , HPA030291: , HPA030292: " "unprognostic (6.56e-2)" "unprognostic (7.62e-2)" "unprognostic (1.72e-1)" "unprognostic (5.34e-3)" "unprognostic (1.03e-2)" "unprognostic (1.30e-1)" "unprognostic (9.99e-2)" "unprognostic (1.70e-2)" "unprognostic (3.38e-2)" "unprognostic (1.69e-1)" "validated prognostic favorable (4.72e-7)" "validated prognostic favorable (8.44e-4)" "unprognostic (1.80e-2)" "unprognostic (1.24e-1)" "unprognostic (3.98e-2)" "unprognostic (6.63e-2)" "unprognostic (1.81e-1)" "unprognostic (2.24e-2)" "unprognostic (1.66e-1)" "unprognostic (1.54e-2)" "unprognostic (4.08e-3)" "unprognostic (4.31e-2)" "unprognostic (1.46e-1)" "unprognostic (1.35e-1)" "unprognostic (3.01e-2)" "potential prognostic favorable (9.40e-5)" "unprognostic (2.40e-1)" "unprognostic (3.61e-1)" "unprognostic (4.68e-2)" "unprognostic (1.25e-1)" "unprognostic (1.02e-1)" NCOR1 "hCIT529I10, hN-CoR, KIAA1047, MGC104216, N-CoR, PPP1R109, TRAC1" ENSG00000141027 "Nuclear receptor corepressor 1" O75376 17 16029065-16218185 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043246, HPA050288, HPA051168, CAB072830" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 32: Basophils - Transcription" "Cluster 76: Non-specific - Metabolism" "Cluster 16: Non-specific - Transcription" "Cluster 42: Non-specific - Unknown function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 128 Nucleoplasm Cytosol "CAB072830: , HPA043246: , HPA050288: , HPA051168: " "unprognostic (1.08e-1)" "unprognostic (8.02e-2)" "unprognostic (1.64e-1)" "unprognostic (1.13e-1)" "unprognostic (5.09e-2)" "unprognostic (3.00e-2)" "unprognostic (5.02e-2)" "unprognostic (3.30e-2)" "unprognostic (4.49e-2)" "unprognostic (7.67e-3)" "validated prognostic favorable (7.87e-9)" "validated prognostic favorable (4.87e-4)" "unprognostic (1.28e-1)" "unprognostic (1.34e-1)" "unprognostic (2.18e-1)" "unprognostic (1.30e-1)" "unprognostic (1.52e-1)" "unprognostic (2.62e-2)" "unprognostic (4.86e-2)" "unprognostic (1.82e-1)" "unprognostic (4.08e-2)" "unprognostic (6.60e-3)" "unprognostic (2.60e-2)" "unprognostic (1.21e-1)" "unprognostic (3.60e-2)" "unprognostic (1.89e-1)" "unprognostic (2.65e-2)" "unprognostic (1.74e-2)" "unprognostic (2.60e-1)" "unprognostic (9.59e-2)" "unprognostic (1.17e-1)" NCOR2 "CTG26, SMRT, SMRTE, TNRC14, TRAC-1" ENSG00000196498 "Nuclear receptor corepressor 2" Q9Y618 12 124324415-124567612 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 6.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001928 Approved Supported Nucleoplasm NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 24: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 100 Nucleoplasm "HPA001928: " "unprognostic (8.84e-2)" "unprognostic (8.65e-2)" "unprognostic (8.05e-2)" "potential prognostic unfavorable (3.73e-4)" "unprognostic (1.84e-1)" "unprognostic (6.34e-3)" "unprognostic (9.51e-2)" "unprognostic (1.62e-1)" "unprognostic (8.22e-2)" "unprognostic (4.02e-2)" "unprognostic (8.99e-2)" "unprognostic (3.23e-2)" "unprognostic (3.88e-1)" "unprognostic (2.28e-2)" "unprognostic (1.31e-1)" "unprognostic (5.78e-2)" "unprognostic (2.22e-2)" "unprognostic (6.34e-2)" "unprognostic (2.90e-1)" "unprognostic (1.02e-3)" "unprognostic (2.02e-1)" "unprognostic (7.74e-3)" "unprognostic (6.10e-3)" "unprognostic (1.94e-1)" "unprognostic (4.98e-2)" "unprognostic (2.89e-3)" "unprognostic (3.08e-2)" "unprognostic (2.80e-2)" "unprognostic (2.65e-1)" "unprognostic (1.90e-2)" "unprognostic (1.83e-1)" NCR1 "CD335, LY94, NK-p46, NKP46" ENSG00000189430 "Natural cytotoxicity triggering receptor 1" O76036 19 54906148-54916140 "CD markers, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 4 "lymphoid tissue: 3.3" "Cell type enriched" "Detected in some" 23 "NK-cells: 24.0" "Cell type enriched" "Detected in single" 37 "leukocyte: 32.4" "Not detected" "Not detected" "Region enriched" "Detected in single" 8 "cerebral cortex: 2.4" "Immune cell enriched" "Detected in single" 4 "NK-cell: 1.1" "Lineage enriched" "Detected in single" 4 "NK-cells: 1.1" "Not detected" "Not detected" "Liver - NK-cells (Liver), Lung - NK-cells (Lung), Spleen - NK-cells (Spleen), Thyroid gland - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 102: Non-specific - Mixed function" 1 "unprognostic (1.40e-1)" NCR2 "CD336, LY95, NK-p44" ENSG00000096264 "Natural cytotoxicity triggering receptor 2" O95944 6 41335608-41350889 "CD markers, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Innate lymphoid cells: 8.8;NK-cells: 11.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 17 "NK-cell: 1.7;plasmacytoid DC: 4.9" "Group enriched" "Detected in many" 17 "dendritic cells: 4.9;NK-cells: 1.7" "Group enriched" "Detected in some" 23 "Leukemia: 1.3;lymphoma: 3.3" "Not detected" "Not detected" HPA067249 Uncertain NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 45: Non-specific - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 2 "HPA067249: " NCR3 "1C7, CD337, LY117, NKp30" ENSG00000204475 "Natural cytotoxicity triggering receptor 3" O14931 6 31588895-31593006 "CD markers, Predicted membrane proteins" Immunity Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 3.8;intestine: 5.2;lymphoid tissue: 15.5" "Cell type enhanced" "Detected in some" "B-cells: 11.0;Innate lymphoid cells: 17.3;NK-cells: 45.2;T-cells: 13.1" "Cell type enriched" "Detected in single" 121 "leukocyte: 22.8" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 275.0" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 21 "Leukemia: 2.2;lymphoma: 2.0" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Thyroid gland - T-cells" "Low region specificity" "Detected in many" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 5 "unprognostic (2.62e-3)" NCR3LG1 "B7-H6, DKFZp686O24166" ENSG00000188211 "Natural killer cell cytotoxicity receptor 3 ligand 1" Q68D85 11 17351800-17377341 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 6.0;parathyroid gland: 7.0" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 51.4;Epicardial cells: 113.7;monocytes: 41.3;Retinal ganglion cells: 50.2" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Kidney Chromophobe (TCGA): 8.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Macrophages, Testis - Early spermatids, Testis - Late spermatids" HPA024137 Uncertain NA NA 19000 "Cluster 77: Intestine - Digestion" "Cluster 5: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 19 "HPA024137: " "unprognostic (1.06e-1)" "unprognostic (2.42e-3)" "unprognostic (1.38e-3)" "unprognostic (9.96e-2)" "potential prognostic favorable (1.64e-10)" "unprognostic (5.28e-3)" "unprognostic (2.51e-2)" "unprognostic (1.48e-1)" "unprognostic (5.82e-2)" "unprognostic (3.36e-1)" "potential prognostic favorable (1.13e-5)" "unprognostic (9.14e-2)" "unprognostic (9.55e-3)" NCS1 "FREQ, NCS-1" ENSG00000107130 "Neuronal calcium sensor 1" P62166 9 130172404-130237303 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 357.2" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 63.4;Ependymal cells: 61.2;Proximal tubule cells: 64.5;Retinal amacrine cells: 69.4;Retinal horizontal cells: 70.1;Smooth muscle cells: 150.9;Vascular smooth muscle cells: 65.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Skin - Keratinocyte (granular), Spleen - Smooth muscle cells, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018587, HPA019713" Enhanced Supported Supported "Vesicles,Plasma membrane,Cytosol" NA NA 17000 "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 62: Smooth muscle cells - Muscle contraction" 36 "Plasma membrane" "Vesicles, Cytosol" "CAB018587: , HPA019713: " "unprognostic (6.33e-2)" "unprognostic (2.04e-3)" "unprognostic (3.19e-2)" "unprognostic (1.35e-1)" "unprognostic (9.55e-3)" "unprognostic (1.83e-1)" "unprognostic (2.70e-1)" "unprognostic (2.50e-3)" "unprognostic (1.02e-1)" "unprognostic (1.71e-1)" "unprognostic (1.55e-1)" "potential prognostic unfavorable (7.13e-4)" "unprognostic (2.50e-1)" "unprognostic (3.77e-3)" "unprognostic (4.11e-3)" "unprognostic (7.68e-3)" "unprognostic (5.67e-3)" "unprognostic (2.51e-2)" "unprognostic (7.46e-2)" "unprognostic (3.28e-3)" "unprognostic (1.72e-1)" "unprognostic (2.21e-1)" "unprognostic (4.84e-1)" "unprognostic (2.63e-1)" "unprognostic (2.18e-1)" "unprognostic (2.78e-2)" "unprognostic (5.41e-1)" "unprognostic (1.97e-1)" "unprognostic (1.26e-1)" "unprognostic (9.96e-3)" "unprognostic (1.69e-1)" NCSTN "APH2, KIAA0253" ENSG00000162736 Nicastrin Q92542 1 160343294-160358952 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Notch signaling pathway" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 126.2;Extravillous trophoblasts: 140.6;Neutrophils: 116.3;Syncytiotrophoblasts: 183.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB021982, HPA054846, HPA070642" Approved Approved Cytosol NA NA 120000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 27: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 18 Cytosol "CAB021982: , HPA054846: , HPA070642: " "unprognostic (7.08e-2)" "unprognostic (8.27e-3)" "unprognostic (2.15e-2)" "unprognostic (3.19e-3)" "unprognostic (2.65e-2)" "unprognostic (1.84e-1)" "unprognostic (3.40e-1)" "unprognostic (6.90e-3)" "unprognostic (8.25e-2)" "unprognostic (3.22e-2)" "unprognostic (2.01e-2)" "unprognostic (1.75e-1)" "unprognostic (1.50e-2)" "unprognostic (5.15e-3)" "unprognostic (1.96e-2)" "unprognostic (2.01e-1)" "unprognostic (1.72e-2)" "unprognostic (1.62e-1)" "unprognostic (1.66e-1)" "unprognostic (6.01e-2)" "unprognostic (2.61e-1)" "unprognostic (7.57e-2)" "unprognostic (9.00e-2)" "unprognostic (2.06e-1)" "unprognostic (2.27e-2)" "unprognostic (1.60e-1)" "unprognostic (1.04e-1)" "unprognostic (1.35e-1)" "unprognostic (1.51e-1)" "unprognostic (7.01e-3)" "unprognostic (2.48e-1)" NDC1 "FLJ10407, NET3, TMEM48" ENSG00000058804 "NDC1 transmembrane nucleoporin" Q9BTX1 1 53765478-53838463 "Essential proteins, Metabolic proteins, Predicted membrane proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 84.7;Monocyte progenitors: 83.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069751, HPA070882" Approved Supported "Nuclear membrane,Plasma membrane,Actin filaments" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 55: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 27: Non-specific - Cell proliferation" 18 "Nuclear membrane" "Plasma membrane, Actin filaments" "HPA069751: , HPA070882: " "unprognostic (8.06e-2)" "unprognostic (1.35e-1)" "unprognostic (2.13e-2)" "potential prognostic favorable (3.06e-5)" "unprognostic (3.43e-1)" "unprognostic (2.46e-1)" "unprognostic (4.36e-1)" "unprognostic (4.17e-2)" "unprognostic (1.19e-3)" "potential prognostic favorable (7.35e-5)" "unprognostic (3.00e-1)" "unprognostic (3.01e-2)" "potential prognostic unfavorable (3.13e-8)" "potential prognostic unfavorable (1.22e-5)" "unprognostic (1.57e-3)" "unprognostic (7.26e-3)" "unprognostic (7.76e-3)" "unprognostic (7.47e-2)" "unprognostic (1.74e-2)" "potential prognostic unfavorable (4.18e-4)" "unprognostic (1.23e-1)" "unprognostic (5.82e-2)" "unprognostic (3.69e-3)" "unprognostic (4.55e-2)" "unprognostic (1.85e-2)" "unprognostic (4.25e-2)" "unprognostic (5.19e-2)" "unprognostic (4.53e-2)" "unprognostic (2.49e-1)" NDC80 "HEC, HEC1, hsNDC80, KNTC2, TID3" ENSG00000080986 "NDC80 kinetochore complex component" O14777 18 2571557-2616635 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 29.4;lymphoid tissue: 27.2" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 71.9;Enteric transient amplifying cells: 29.6;Erythrocyte progenitors: 80.5;Extravillous trophoblasts: 31.1;Late primary spermatocytes: 73.0;Megakaryocyte progenitors: 62.0;Monocyte progenitors: 101.4;Neutrophil progenitors: 50.2;Oocytes: 82.9" "Group enriched" "Detected in some" 5 "fibroblast: 7.8;leukocyte: 8.8;pericyte: 3.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 7.1;granulocytes: 8.4;T-cells: 11.3" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Kidney - Fibroblasts, Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA066330 Supported "Nucleoplasm,Nuclear speckles,Centrosome,Cytosol" NA Yes "Cluster 43: Non-specific - Transcription & Translation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 37: Neurons - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Non-specific - Cell proliferation" 114 "Nucleoplasm, Nuclear speckles" "Centrosome, Cytosol" "HPA066330: " "unprognostic (1.23e-1)" "unprognostic (2.26e-1)" "unprognostic (3.72e-1)" "unprognostic (7.83e-2)" "unprognostic (2.84e-1)" "unprognostic (2.00e-2)" "unprognostic (1.79e-1)" "unprognostic (1.56e-2)" "unprognostic (4.33e-2)" "unprognostic (2.33e-3)" "potential prognostic unfavorable (2.06e-9)" "unprognostic (2.62e-2)" "potential prognostic unfavorable (4.98e-4)" "validated prognostic unfavorable (4.20e-7)" "validated prognostic unfavorable (2.19e-8)" "potential prognostic unfavorable (3.45e-4)" "unprognostic (4.54e-2)" "unprognostic (1.35e-2)" "unprognostic (8.94e-2)" "unprognostic (3.93e-2)" "unprognostic (2.92e-1)" "unprognostic (4.03e-3)" "unprognostic (4.61e-2)" "unprognostic (2.42e-2)" "unprognostic (3.47e-1)" "unprognostic (2.64e-1)" "unprognostic (3.38e-3)" "unprognostic (8.57e-3)" "unprognostic (2.14e-1)" "unprognostic (6.79e-2)" "unprognostic (1.24e-1)" NDE1 "FLJ20101, NDE, nudE" ENSG00000072864 "NudE neurodevelopment protein 1" Q9NXR1 16 15643267-15734691 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Mitosis, Neurogenesis" "Developmental protein" Lissencephaly "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 27.4;Distal convoluted tubule cells: 23.3;Ependymal cells: 64.3;Late spermatids: 23.6;Microglia: 40.3;Oligodendrocytes: 160.5;Oocytes: 23.0;Papillary tip epithelial cells: 23.7;Podocytes: 27.9" "Cell type enhanced" "Detected in all" "oligodendrocyte: 225.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "granulocytes: 22.2;monocytes: 11.9;NK-cells: 8.6" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Liver - Vascular endothelial cells, Skin - Keratinocyte (other), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024075 Approved NA Yes "Cluster 7: Non-specific - Innate immune response" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 102: Non-specific - Mixed function" 16 "HPA024075: " "unprognostic (4.18e-1)" "unprognostic (1.38e-1)" "unprognostic (4.97e-1)" "unprognostic (7.04e-2)" "unprognostic (1.43e-1)" "unprognostic (4.12e-3)" "unprognostic (1.09e-1)" "unprognostic (2.62e-1)" "unprognostic (1.61e-1)" "potential prognostic unfavorable (5.49e-7)" "unprognostic (2.11e-1)" "unprognostic (5.61e-2)" "unprognostic (3.66e-1)" "potential prognostic unfavorable (2.57e-5)" "unprognostic (7.13e-3)" "unprognostic (6.37e-3)" "unprognostic (4.58e-3)" "unprognostic (1.43e-1)" "unprognostic (5.71e-2)" "unprognostic (4.70e-2)" "unprognostic (2.05e-1)" "unprognostic (3.60e-3)" "unprognostic (7.13e-2)" "unprognostic (2.62e-2)" "unprognostic (7.48e-2)" "unprognostic (9.06e-2)" "unprognostic (3.66e-1)" "unprognostic (1.91e-2)" "unprognostic (2.20e-1)" "unprognostic (8.65e-2)" "unprognostic (3.11e-2)" NDEL1 "MITAP1, NDE1L1, NDE2, NUDEL" ENSG00000166579 "NudE neurodevelopment protein 1 like 1" Q9GZM8 17 8413131-8490411 "Predicted intracellular proteins" "Differentiation, Neurogenesis, Transport" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial luminal cells: 453.8;Epicardial cells: 402.5;Mast cells: 514.8;Neutrophils: 1302.2;Pituicytes/FSCs: 406.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Lineage enriched" "Detected in all" 5 "granulocytes: 176.0" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary gland basal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017916 Approved NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 15: Bone marrow - Innate immune response" "Cluster 14: Neurons - Synaptic function" "Cluster 42: Non-specific - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" 111 "HPA017916: " "unprognostic (5.53e-3)" "unprognostic (3.51e-2)" "unprognostic (6.11e-2)" "unprognostic (1.42e-2)" "unprognostic (1.68e-1)" "unprognostic (1.47e-1)" "unprognostic (3.58e-2)" "unprognostic (3.92e-1)" "unprognostic (6.49e-2)" "unprognostic (7.79e-2)" "validated prognostic favorable (1.82e-5)" "validated prognostic favorable (3.88e-4)" "unprognostic (3.94e-2)" "unprognostic (9.39e-2)" "unprognostic (4.28e-2)" "unprognostic (3.62e-3)" "unprognostic (7.82e-2)" "unprognostic (6.03e-2)" "unprognostic (1.65e-1)" "unprognostic (7.23e-2)" "unprognostic (9.06e-3)" "unprognostic (5.64e-2)" "potential prognostic unfavorable (5.85e-4)" "unprognostic (4.23e-2)" "unprognostic (1.71e-1)" "unprognostic (1.72e-1)" "unprognostic (9.81e-2)" "unprognostic (3.16e-2)" "unprognostic (5.35e-1)" "unprognostic (3.05e-1)" "unprognostic (2.34e-2)" NDFIP1 "MGC10924, N4WBP5" ENSG00000131507 "Nedd4 family interacting protein 1" Q9BT67 5 142108779-142154440 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009682 Approved "Intracellular and membrane" "No annotated function" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 65: Brain - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 9: T-cells - Adaptive immunity: Regulation" 11 "HPA009682: " "unprognostic (9.88e-3)" "unprognostic (3.74e-3)" "unprognostic (6.08e-2)" "unprognostic (8.22e-3)" "unprognostic (9.55e-2)" "unprognostic (2.62e-2)" "unprognostic (7.54e-3)" "potential prognostic unfavorable (7.15e-6)" "potential prognostic unfavorable (2.69e-4)" "unprognostic (1.29e-2)" "potential prognostic favorable (4.56e-10)" "unprognostic (2.06e-2)" "unprognostic (6.67e-2)" "unprognostic (6.46e-2)" "potential prognostic favorable (9.93e-4)" "unprognostic (1.27e-1)" "unprognostic (7.56e-3)" "unprognostic (4.20e-2)" "unprognostic (4.77e-2)" "unprognostic (2.14e-1)" "unprognostic (3.03e-3)" "unprognostic (1.33e-1)" "unprognostic (7.12e-2)" "unprognostic (6.10e-2)" "unprognostic (3.69e-1)" "unprognostic (1.26e-2)" "unprognostic (7.18e-2)" "unprognostic (2.47e-1)" "unprognostic (1.36e-1)" "unprognostic (1.46e-1)" "unprognostic (3.28e-1)" NDFIP2 "KIAA1165, N4wbp5a" ENSG00000102471 "Nedd4 family interacting protein 2" Q9NV92 13 79481155-79556077 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 404.4;Esophageal apical cells: 719.9;Late spermatids: 495.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 28.4" "Lineage enriched" "Detected in many" 4 "granulocytes: 28.4" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary gland basal cells, Skin - Keratinocyte (other), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009160 Uncertain Supported Vesicles NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 76: Non-specific - Metabolism" "Cluster 51: Neurons - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 84: Apical squamous epithelium - Cornification" 10 Vesicles "HPA009160: " "unprognostic (1.87e-1)" "unprognostic (6.80e-2)" "potential prognostic unfavorable (4.09e-4)" "unprognostic (1.09e-1)" "unprognostic (3.79e-2)" "unprognostic (8.36e-2)" "unprognostic (8.74e-2)" "unprognostic (1.02e-1)" "potential prognostic unfavorable (9.83e-4)" "unprognostic (4.34e-2)" "potential prognostic favorable (1.73e-11)" "unprognostic (8.89e-2)" "unprognostic (3.80e-1)" "unprognostic (2.70e-1)" "unprognostic (6.57e-2)" "unprognostic (1.30e-3)" "unprognostic (3.48e-3)" "unprognostic (2.83e-1)" "unprognostic (1.69e-1)" "unprognostic (1.84e-1)" "unprognostic (1.40e-2)" "unprognostic (3.60e-3)" "unprognostic (3.74e-2)" "unprognostic (2.23e-2)" "unprognostic (1.17e-2)" "unprognostic (1.74e-1)" "unprognostic (1.06e-1)" "unprognostic (6.38e-2)" "unprognostic (1.58e-1)" "unprognostic (1.33e-1)" "unprognostic (2.68e-2)" NDN "HsT16328, PWCR" ENSG00000182636 "Necdin, MAGE family member" Q99608 15 23685400-23687305 "Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Growth regulation, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 20.7;Brain inhibitory neurons: 44.2;Ependymal cells: 20.8;Oligodendrocyte progenitor cells: 22.7;Oligodendrocytes: 22.8;Other brain neurons: 113.7;Podocytes: 10.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 72.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.5" "Lineage enriched" "Detected in single" 5 "dendritic cells: 1.5" "Cancer enhanced" "Detected in many" "testis cancer: 52.9" "Adrenal gland - Adrenal cortex cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074457 Approved Nucleoplasm,Cytosol NA NA "Cluster 75: Ovary - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 98: Neurons - Neurotransmission & signaling" 57 "Nucleoplasm, Cytosol" "HPA074457: " "unprognostic (1.69e-3)" "unprognostic (2.46e-1)" "unprognostic (7.01e-2)" "unprognostic (6.53e-2)" "unprognostic (1.45e-1)" "unprognostic (1.73e-1)" "unprognostic (1.05e-1)" "potential prognostic favorable (2.51e-5)" "unprognostic (8.92e-2)" "unprognostic (1.41e-3)" "unprognostic (5.14e-2)" "unprognostic (1.31e-1)" "unprognostic (1.10e-1)" "unprognostic (6.39e-2)" "unprognostic (6.40e-2)" "unprognostic (3.01e-2)" "unprognostic (1.36e-1)" "unprognostic (2.47e-3)" "unprognostic (7.65e-2)" "unprognostic (7.03e-2)" "unprognostic (5.44e-2)" "unprognostic (4.58e-2)" "unprognostic (6.85e-2)" "unprognostic (1.34e-1)" "unprognostic (2.21e-3)" "unprognostic (1.73e-1)" "unprognostic (3.07e-2)" "unprognostic (1.09e-2)" "unprognostic (2.27e-1)" "unprognostic (2.23e-1)" "unprognostic (2.62e-2)" NDNF "C4orf31, FLJ23191" ENSG00000173376 "Neuron derived neurotrophic factor" Q8TB73 4 121035613-121073021 "Disease related genes, Human disease related genes, Predicted secreted proteins" Neurogenesis "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 100.4;placenta: 56.5;retina: 53.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 143.3;Alveolar cells type 2: 65.2;Choroid plexus epithelial cells: 136.0;Cone photoreceptor cells: 68.3;Corticotrophs: 143.2;Early spermatids: 304.6;Late spermatids: 291.7;Podocytes: 470.5;Retinal bipolar cells: 109.3" "Cell type enhanced" "Detected in many" "CGE interneuron: 34.8;choroid plexus epithelial cell: 70.0;fibroblast: 27.8" "Cancer enriched" "Detected in many" 5 "Lung Adenocarcinoma (TCGA): 37.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 15.6" "Adrenal gland - Adrenal cortex cells, Kidney - Podocytes, Liver - Vascular endothelial cells, Lung - Alveolar cells type 1, Prostate - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Group enriched" "Detected in all" 4 "basal ganglia: 11.1;olfactory bulb: 34.0" "Low region specificity" "Detected in all" HPA048881 Supported Vesicles "Secreted in other tissues" Other NA NA 130000 "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 20: Myeloma - Immune response" "Cluster 57: Podocytes - Glomerular filtration" Vesicles "HPA048881: " "unprognostic (1.42e-1)" "unprognostic (3.63e-1)" "unprognostic (2.85e-1)" "unprognostic (7.84e-2)" "unprognostic (6.62e-2)" "unprognostic (2.21e-1)" "unprognostic (1.90e-1)" "unprognostic (5.21e-2)" "unprognostic (3.08e-1)" "potential prognostic unfavorable (5.79e-4)" "potential prognostic favorable (6.39e-4)" "unprognostic (8.72e-2)" "unprognostic (1.11e-2)" "unprognostic (8.17e-2)" "unprognostic (1.56e-3)" "unprognostic (3.10e-2)" "unprognostic (1.24e-1)" "unprognostic (5.38e-2)" "unprognostic (3.38e-1)" "unprognostic (1.08e-1)" "unprognostic (1.70e-3)" "unprognostic (3.47e-1)" NDOR1 "bA350O14.9, CIAE1, NR1" ENSG00000188566 "NADPH dependent diflavin oxidoreductase 1" Q9UHB4 9 137205685-137219361 "Essential proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024504 Approved Approved "Nucleoplasm,Intermediate filaments,Cytosol" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 6: Non-specific - Immune response" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Transcription" 24 Cytosol "Nucleoplasm, Intermediate filaments" "HPA024504: " "unprognostic (3.64e-1)" "unprognostic (8.06e-2)" "unprognostic (3.43e-1)" "unprognostic (9.59e-2)" "unprognostic (4.65e-2)" "unprognostic (2.67e-1)" "unprognostic (1.79e-1)" "unprognostic (1.02e-2)" "potential prognostic favorable (8.64e-4)" "unprognostic (8.80e-2)" "unprognostic (2.24e-3)" "unprognostic (2.05e-2)" "unprognostic (3.41e-2)" "unprognostic (1.75e-3)" "unprognostic (1.73e-2)" "unprognostic (3.74e-1)" "unprognostic (1.18e-1)" "unprognostic (3.35e-2)" "unprognostic (1.46e-2)" "unprognostic (2.36e-1)" "unprognostic (1.19e-2)" "unprognostic (1.23e-3)" "unprognostic (3.13e-1)" "unprognostic (1.89e-1)" "unprognostic (3.55e-2)" "unprognostic (2.08e-3)" "unprognostic (1.11e-1)" "unprognostic (1.21e-2)" "unprognostic (2.86e-1)" "unprognostic (5.36e-2)" "unprognostic (6.93e-2)" NDP "EVR2, norrin" ENSG00000124479 "Norrin cystine knot growth factor NDP" Q00604 X 43948776-43973395 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Sensory transduction, Vision, Wnt signaling pathway" "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.4;ovary: 31.8" "Cell type enhanced" "Detected in some" "Astrocytes: 34.9;Bergmann glia: 13.0;Decidual stromal cells: 52.9;Endometrial luminal cells: 40.5;Epididymal principal cells: 15.3;Granulosa cells: 89.2;Müller glia: 88.7;Oligodendrocytes: 13.1;Ovarian stromal cells: 49.1" "Cell type enhanced" "Detected in many" "astrocyte: 36.7;Bergmann glia: 19.8" "Cancer enriched" "Detected in many" 5 "Glioblastoma Multiforme (TCGA): 46.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Brain cancer: 9.5" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003095 Supported Nucleoplasm,Nucleoli,Vesicles "Secreted to extracellular matrix" Other NA NA "Cluster 65: Brain - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 72: Neuronal - Signal transduction" "Cluster 94: Gonadal somatic cells - Mixed function" 13 Vesicles "Nucleoplasm, Nucleoli" "HPA003095: " "unprognostic (4.09e-2)" "unprognostic (4.92e-2)" "unprognostic (9.24e-3)" "unprognostic (2.77e-1)" "unprognostic (1.09e-1)" "unprognostic (1.37e-1)" "unprognostic (1.32e-1)" "unprognostic (2.46e-1)" "unprognostic (2.99e-1)" "unprognostic (2.58e-1)" "unprognostic (8.67e-2)" "unprognostic (2.63e-1)" "unprognostic (9.57e-3)" NDRG1 "CAP43, DRG1, NDR1, RTP, TDD5" ENSG00000104419 "N-myc downstream regulated 1" Q92597 8 133237175-133302022 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes, Charcot-Marie-Tooth disease, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 360.2;Esophageal apical cells: 750.7;Esophageal suprabasal cells: 649.7;Ocular epithelial cells: 493.1;Pancreatic acinar cells: 374.3;Prostatic hillock cells: 518.4;Renal connecting tubule cells: 411.5;Suprabasal keratinocytes: 857.9" "Cell type enhanced" "Detected in many" "endothelial cell: 291.8;oligodendrocyte: 227.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney cancer: 414.2" "Colon - Endothelial cells, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006881 Approved Supported "Microtubules,Cytosol,Calyx,Connecting piece,Mid piece,Principal piece,End piece" NA NA 120000 "Cluster 13: Non-specific - Mitochondria" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 57 "Cytosol, Connecting piece, Mid piece, Principal piece, End piece" "Microtubules, Calyx" "HPA006881: " "unprognostic (2.54e-1)" "potential prognostic unfavorable (7.24e-4)" "unprognostic (4.02e-1)" "unprognostic (6.58e-3)" "unprognostic (1.54e-1)" "unprognostic (1.96e-1)" "unprognostic (4.88e-3)" "potential prognostic unfavorable (1.31e-4)" "unprognostic (2.71e-2)" "unprognostic (2.83e-2)" "potential prognostic favorable (1.14e-6)" "unprognostic (1.26e-2)" "unprognostic (4.10e-2)" "unprognostic (1.26e-3)" "potential prognostic unfavorable (1.79e-7)" "potential prognostic unfavorable (6.06e-4)" "unprognostic (3.88e-3)" "unprognostic (1.06e-2)" "unprognostic (2.41e-1)" "unprognostic (3.15e-2)" "unprognostic (1.73e-1)" "unprognostic (6.48e-2)" "unprognostic (1.67e-3)" "unprognostic (2.91e-1)" "unprognostic (4.13e-2)" "unprognostic (1.24e-1)" "unprognostic (2.58e-2)" "unprognostic (3.30e-2)" "unprognostic (2.03e-1)" "unprognostic (1.25e-2)" "unprognostic (2.17e-1)" NDRG2 "KIAA1248, SYLD" ENSG00000165795 "NDRG family member 2" Q9UN36 14 21016763-21070872 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis, Wnt signaling pathway" "Developmental protein" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 2060.1;salivary gland: 1953.8;skeletal muscle: 1707.9;tongue: 1485.5" "Cell type enhanced" "Detected in many" "Astrocytes: 392.7;Bergmann glia: 797.1;Breast secretory cells: 532.1;Epididymal principal cells: 408.9;Esophageal apical cells: 729.6;Lacrimal acinar cells: 482.8;Müller glia: 368.8;Salivary acinar cells: 787.0;Schwann cells: 503.8;Thymic myoid cells: 439.2" "Group enriched" "Detected in all" 4 "astrocyte: 433.8;Bergmann glia: 875.3" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 521.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 11 "myeloid DC: 204.5" "Lineage enriched" "Detected in all" 11 "dendritic cells: 204.5" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Kidney - Fibroblasts, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002896, HPA003590, CAB017491" Enhanced Approved "Nucleoplasm,Centriolar satellite,Cytosol" NA NA 470000 "Cluster 13: Non-specific - Mitochondria" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 4 "Centriolar satellite" "Nucleoplasm, Cytosol" "CAB017491: , HPA002896: , HPA003590: " "unprognostic (4.98e-2)" "unprognostic (1.56e-2)" "unprognostic (4.70e-2)" "unprognostic (7.46e-2)" "unprognostic (1.61e-2)" "unprognostic (4.20e-2)" "unprognostic (1.68e-2)" "unprognostic (1.59e-2)" "unprognostic (2.33e-1)" "unprognostic (1.81e-1)" "validated prognostic favorable (2.25e-12)" "validated prognostic favorable (1.12e-5)" "potential prognostic favorable (1.98e-5)" "unprognostic (1.86e-2)" "unprognostic (1.96e-2)" "unprognostic (2.80e-3)" "unprognostic (2.21e-1)" "unprognostic (1.93e-1)" "unprognostic (2.48e-1)" "unprognostic (9.14e-2)" "unprognostic (2.47e-1)" "unprognostic (2.49e-1)" "unprognostic (5.02e-2)" "unprognostic (6.33e-2)" "unprognostic (1.77e-1)" "unprognostic (2.02e-3)" "unprognostic (1.37e-2)" "unprognostic (1.25e-1)" "unprognostic (1.32e-1)" "unprognostic (1.35e-3)" "unprognostic (7.66e-2)" NDRG3 ENSG00000101079 "NDRG family member 3" Q9UGV2 20 36651766-36746090 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 147.7" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 225.6;Early spermatids: 1128.6;Late primary spermatocytes: 419.0;Late spermatids: 458.0;Rod photoreceptor cells: 194.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017851, HPA018256" Enhanced Approved Vesicles,Cytosol NA NA 9700 "Cluster 33: Non-specific - ATP binding" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 37: Neurons - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 2 Cytosol Vesicles "HPA017851: , HPA018256: " "unprognostic (8.28e-3)" "unprognostic (1.31e-3)" "unprognostic (9.29e-2)" "unprognostic (6.95e-2)" "unprognostic (7.46e-2)" "unprognostic (2.61e-2)" "unprognostic (2.63e-1)" "unprognostic (3.27e-2)" "unprognostic (2.59e-1)" "potential prognostic unfavorable (4.56e-4)" "unprognostic (2.73e-3)" "unprognostic (7.83e-2)" "unprognostic (1.41e-1)" "potential prognostic unfavorable (1.41e-4)" "unprognostic (2.25e-3)" "unprognostic (5.02e-2)" "unprognostic (2.98e-1)" "unprognostic (1.22e-1)" "unprognostic (2.24e-1)" "potential prognostic unfavorable (8.60e-6)" "unprognostic (1.32e-2)" "unprognostic (1.83e-2)" "unprognostic (1.58e-1)" "unprognostic (1.43e-1)" "unprognostic (3.73e-2)" "unprognostic (1.31e-2)" "unprognostic (6.17e-3)" "unprognostic (7.29e-2)" "unprognostic (1.24e-1)" "unprognostic (3.68e-1)" "unprognostic (8.68e-2)" NDRG4 "KIAA1180, SMAP-8" ENSG00000103034 "NDRG family member 4" Q9ULP0 16 58462846-58513628 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 347.4;heart muscle: 326.5" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 149.0;Adrenal medulla cells: 265.9;Bergmann glia: 254.6;Brain excitatory neurons: 141.6;Brain inhibitory neurons: 143.1;Cardiomyocytes: 264.1;Corticotrophs: 153.5;Epididymal basal cells: 115.7;Other brain neurons: 109.8;Retinal amacrine cells: 105.7;Retinal ganglion cells: 181.6;Retinal horizontal cells: 454.8;Sertoli cells: 196.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 84.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Neuroblastoma: 65.0;Rhabdoid: 37.5" "Adipose subcutaneous - Adipocytes (Subcutaneous), Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Pancreas - Beta cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015313, HPA015779" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 24: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 9 Cytosol "Plasma membrane" "HPA015313: , HPA015779: " "unprognostic (1.86e-1)" "unprognostic (1.34e-1)" "unprognostic (2.08e-1)" "unprognostic (4.04e-1)" "unprognostic (1.49e-1)" "unprognostic (1.19e-1)" "unprognostic (4.22e-1)" "unprognostic (7.78e-2)" "unprognostic (2.35e-1)" "unprognostic (9.94e-2)" "unprognostic (1.81e-1)" "unprognostic (9.48e-2)" "unprognostic (5.98e-2)" "unprognostic (5.11e-2)" "unprognostic (1.10e-1)" "unprognostic (1.82e-2)" "unprognostic (6.67e-2)" "unprognostic (1.34e-1)" "unprognostic (7.76e-2)" "unprognostic (2.51e-1)" "unprognostic (4.97e-1)" "unprognostic (1.36e-2)" "unprognostic (3.02e-3)" "unprognostic (9.56e-2)" "unprognostic (1.33e-1)" "unprognostic (1.49e-2)" "unprognostic (8.29e-2)" "unprognostic (5.59e-3)" "unprognostic (1.75e-1)" "unprognostic (5.02e-3)" "unprognostic (3.95e-2)" NDST1 "HSST, NST1" ENSG00000070614 "N-deacetylase and N-sulfotransferase 1" P52848 5 150485818-150558211 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Inflammatory response" "Hydrolase, Multifunctional enzyme, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 123.6;Breast lactating cells: 110.6;Esophageal apical cells: 103.9;Neutrophils: 127.1;Platelets: 160.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "basophil: 1.4;classical monocyte: 5.5;eosinophil: 3.6;intermediate monocyte: 1.7;myeloid DC: 4.2;neutrophil: 5.4;non-classical monocyte: 4.7" "Group enriched" "Detected in many" 10 "dendritic cells: 4.2;granulocytes: 5.4;monocytes: 5.5" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060532 Approved NA NA 940000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 1 "HPA060532: " "unprognostic (2.62e-1)" "unprognostic (1.69e-1)" "unprognostic (2.95e-1)" "unprognostic (4.10e-3)" "unprognostic (3.91e-1)" "unprognostic (7.47e-2)" "unprognostic (2.49e-1)" "unprognostic (1.71e-1)" "unprognostic (9.16e-2)" "unprognostic (5.41e-3)" "potential prognostic favorable (1.85e-5)" "unprognostic (8.10e-3)" "unprognostic (4.04e-2)" "unprognostic (1.73e-1)" "unprognostic (7.12e-2)" "unprognostic (2.05e-1)" "unprognostic (1.21e-1)" "unprognostic (7.03e-3)" "unprognostic (2.36e-1)" "unprognostic (6.53e-3)" "unprognostic (1.66e-3)" "unprognostic (2.19e-3)" "unprognostic (6.40e-3)" "unprognostic (7.80e-2)" "unprognostic (1.67e-1)" "unprognostic (1.79e-1)" "unprognostic (9.74e-2)" "unprognostic (9.51e-2)" "unprognostic (2.43e-1)" "unprognostic (3.08e-2)" "unprognostic (1.28e-1)" NDST2 "HSST2, NST2" ENSG00000166507 "N-deacetylase and N-sulfotransferase 2" P52849 10 73801911-73811798 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 2.6;Epididymal principal cells: 2.9;Late primary spermatocytes: 2.4;Late spermatids: 5.1;Mast cells: 9.0;Microglia: 3.0;Paneth cells: 3.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051515 Approved Approved Cytosol NA NA 130000 "Cluster 33: Non-specific - ATP binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 15: Non-specific - Transcription" "Cluster 49: HMC-1 - Innate immune response" "Cluster 58: Mast cells - Allergic inflammatory responses" Cytosol "HPA051515: " "unprognostic (8.77e-2)" "unprognostic (1.16e-1)" "unprognostic (9.71e-2)" "unprognostic (1.60e-2)" "unprognostic (1.55e-2)" "unprognostic (1.22e-1)" "unprognostic (2.68e-2)" "potential prognostic favorable (6.41e-5)" "unprognostic (6.93e-2)" "unprognostic (8.85e-2)" "unprognostic (6.51e-2)" "unprognostic (2.01e-2)" "unprognostic (1.07e-1)" "unprognostic (1.11e-2)" "unprognostic (1.33e-1)" "unprognostic (8.85e-3)" "unprognostic (7.43e-2)" "unprognostic (4.25e-2)" "unprognostic (1.40e-1)" "unprognostic (1.28e-2)" "unprognostic (1.10e-1)" "unprognostic (8.75e-3)" "unprognostic (5.39e-2)" "unprognostic (1.06e-1)" "unprognostic (4.81e-2)" "unprognostic (3.65e-1)" "unprognostic (1.77e-1)" "unprognostic (1.96e-1)" "unprognostic (3.01e-1)" "unprognostic (8.58e-2)" "unprognostic (1.02e-1)" NDST3 HSST3 ENSG00000164100 "N-deacetylase and N-sulfotransferase 3" O95803 4 118033618-118258634 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.1;lymphoid tissue: 2.7;retina: 2.5" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 117.0;Brain excitatory neurons: 310.5;Brain inhibitory neurons: 338.8;Ependymal cells: 93.5;Kupffer cells: 518.6;Lactotrophs: 120.8;Other brain neurons: 110.0;Retinal bipolar cells: 254.4;Somatotrophs: 99.4;Thymocytes: 133.8;Thyrotrophs: 94.9" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Leukemia: 1.4" "Adrenal gland - Adrenal medulla cells, Kidney - Ascending Loop of Henle cells, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056189 Uncertain NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 59: Leukemia - T-cell receptor" "Cluster 35: Neurons - Synaptic function & neurogenesis" 4 "HPA056189: " "unprognostic (3.87e-3)" NDST4 ENSG00000138653 "N-deacetylase and N-sulfotransferase 4" Q9H3R1 4 114827763-115113876 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Brain excitatory neurons: 28.6;Brain inhibitory neurons: 54.8;Lactotrophs: 31.0;Other brain neurons: 53.8;Thymic myoid cells: 114.2;Thyrotrophs: 70.3" "Cell type enriched" "Detected in many" 4 "lower rhombic lip: 602.3" "Not detected" "Not detected" "Region enhanced" "Detected in many" "pons: 19.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 6.4;lymphoma: 2.5;Sarcoma: 2.4" "Minor Salivary Gland - Minor salivary gland ductal cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA011129 Uncertain NA NA "Cluster 49: Hindbrain - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 109: Neurons - Neuronal signaling" "HPA011129: " "unprognostic (1.56e-2)" NDUFA1 "CI-MWFE, MWFE" ENSG00000125356 "NADH:ubiquinone oxidoreductase subunit A1" O15239 X 119871832-119876662 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1658.3" "Cell type enhanced" "Detected in many" "Colonocytes: 1316.4;Enterocytes: 1380.3;Hepatocytes: 1151.9;Parietal cells: 2681.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029768, HPA054359" Enhanced Supported Mitochondria,Cytosol No No "Cluster 10: Non-specific - Membrane trafficking" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 36: Non-specific - mRNA processing" "Cluster 97: Non-specific - Cellular respiration" 35 "Mitochondria, Cytosol" "HPA029768: , HPA054359: " "unprognostic (1.98e-1)" "unprognostic (1.38e-2)" "unprognostic (3.92e-2)" "potential prognostic favorable (1.84e-4)" "unprognostic (3.09e-1)" "unprognostic (2.16e-3)" "unprognostic (5.89e-2)" "unprognostic (1.69e-1)" "unprognostic (1.54e-3)" "potential prognostic unfavorable (3.79e-4)" "unprognostic (1.17e-2)" "unprognostic (2.08e-2)" "unprognostic (1.10e-1)" "unprognostic (2.46e-1)" "unprognostic (1.66e-2)" "unprognostic (7.22e-2)" "unprognostic (3.06e-1)" "unprognostic (9.28e-3)" "unprognostic (8.41e-2)" "unprognostic (1.52e-1)" "unprognostic (2.08e-1)" "unprognostic (1.87e-2)" "unprognostic (2.77e-2)" "unprognostic (8.66e-2)" "unprognostic (2.83e-2)" "unprognostic (1.73e-2)" "unprognostic (3.85e-2)" "unprognostic (1.89e-1)" "unprognostic (3.12e-2)" "unprognostic (5.09e-2)" "unprognostic (1.23e-1)" NDUFA10 CI-42k ENSG00000130414 "NADH:ubiquinone oxidoreductase subunit A10" O95299 2 239892450-240025743 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 309.9" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059529, HPA067045, CAB070846" Approved Approved Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 97: Non-specific - Cellular respiration" 33 Mitochondria "CAB070846: , HPA059529: , HPA067045: " "unprognostic (1.95e-2)" "unprognostic (9.02e-2)" "unprognostic (3.54e-2)" "unprognostic (1.92e-1)" "unprognostic (5.00e-2)" "unprognostic (1.71e-2)" "unprognostic (3.38e-1)" "unprognostic (4.38e-2)" "unprognostic (1.96e-1)" "unprognostic (4.49e-2)" "potential prognostic favorable (2.45e-8)" "unprognostic (1.49e-1)" "unprognostic (3.63e-3)" "unprognostic (5.69e-3)" "unprognostic (4.11e-3)" "unprognostic (1.28e-2)" "unprognostic (4.22e-2)" "unprognostic (4.18e-2)" "unprognostic (6.58e-2)" "unprognostic (1.36e-2)" "unprognostic (9.20e-2)" "unprognostic (1.40e-1)" "unprognostic (2.45e-1)" "unprognostic (9.26e-2)" "unprognostic (1.30e-1)" "unprognostic (4.58e-2)" "unprognostic (4.63e-2)" "unprognostic (2.21e-1)" "unprognostic (1.88e-1)" "unprognostic (3.46e-1)" "unprognostic (7.30e-2)" NDUFA11 B14.7 ENSG00000174886 "NADH:ubiquinone oxidoreductase subunit A11" Q86Y39 19 5891276-5904006 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 833.1;Hepatocytes: 621.8;Late spermatids: 602.8;Parietal cells: 712.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072209 Approved "Mitochondria,Perinuclear theca,Principal piece,End piece" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 52: Non-specific - Cellular respiration" "Cluster 27: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 5 "Mitochondria, End piece" "Perinuclear theca, Principal piece" "HPA072209: " "unprognostic (2.23e-1)" "unprognostic (2.66e-1)" "unprognostic (1.89e-2)" "potential prognostic favorable (5.46e-4)" "unprognostic (2.40e-1)" "unprognostic (2.43e-2)" "unprognostic (9.80e-2)" "unprognostic (2.36e-2)" "unprognostic (1.21e-1)" "unprognostic (1.08e-2)" "unprognostic (6.94e-3)" "unprognostic (4.60e-3)" "unprognostic (7.94e-3)" "unprognostic (1.08e-1)" "unprognostic (2.78e-2)" "unprognostic (1.79e-1)" "unprognostic (4.15e-2)" "unprognostic (8.59e-2)" "unprognostic (3.21e-1)" "unprognostic (6.17e-2)" "unprognostic (2.42e-1)" "unprognostic (3.80e-3)" "unprognostic (2.61e-1)" "unprognostic (3.07e-1)" "unprognostic (2.89e-1)" "unprognostic (8.18e-2)" "unprognostic (2.08e-1)" "unprognostic (8.40e-2)" "potential prognostic favorable (6.92e-4)" "unprognostic (5.17e-3)" "unprognostic (1.27e-2)" NDUFA12 "B17.2, DAP13" ENSG00000184752 "NADH:ubiquinone oxidoreductase subunit A12" Q9UI09 12 94895297-95003748 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 522.0;tongue: 528.2" "Cell type enhanced" "Detected in many" "Parietal cells: 466.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039903 Supported Supported Mitochondria,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 14: Neurons - Synaptic function" "Cluster 38: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 55 Mitochondria Cytosol "HPA039903: " "unprognostic (1.02e-1)" "unprognostic (1.52e-2)" "unprognostic (2.27e-2)" "unprognostic (8.73e-3)" "unprognostic (6.47e-3)" "unprognostic (3.40e-2)" "unprognostic (2.67e-1)" "unprognostic (8.67e-2)" "potential prognostic unfavorable (9.08e-4)" "potential prognostic unfavorable (5.56e-4)" "unprognostic (4.36e-2)" "unprognostic (2.62e-1)" "unprognostic (1.80e-2)" "unprognostic (2.00e-3)" "potential prognostic unfavorable (2.17e-5)" "potential prognostic unfavorable (5.48e-4)" "unprognostic (4.96e-2)" "unprognostic (1.24e-1)" "unprognostic (1.47e-1)" "unprognostic (5.25e-2)" "unprognostic (1.43e-2)" "unprognostic (7.66e-2)" "unprognostic (5.44e-3)" "unprognostic (3.42e-2)" "unprognostic (2.45e-2)" "unprognostic (2.30e-1)" "unprognostic (2.08e-1)" "unprognostic (7.84e-2)" "unprognostic (1.33e-1)" "unprognostic (1.65e-1)" "unprognostic (2.56e-1)" NDUFA13 "B16.6, CDA016, CGI-39, GRIM-19, GRIM19" ENSG00000186010 "NADH:ubiquinone oxidoreductase subunit A13" Q9P0J0 19 19515736-19529054 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Apoptosis, Electron transport, Host-virus interaction, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 581.3;Enteric stem cells: 262.1;Enteric transient amplifying cells: 407.3;Enterocytes: 628.5;Epididymal clear cells: 314.4;Epididymal efferent duct absorptive cells: 274.2;Epididymal efferent duct ciliated cells: 254.8;Epididymal principal cells: 631.3;Gastric chief cells: 412.8;Goblet cells: 319.8;Neuroendocrine cells: 288.2;Parietal cells: 963.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041213 Supported Supported Mitochondria NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 23: Non-specific - Transcription" "Cluster 15: Non-specific - Protein processing" 83 Mitochondria "HPA041213: " "unprognostic (9.83e-2)" "unprognostic (3.01e-1)" "unprognostic (2.44e-2)" "potential prognostic favorable (5.60e-4)" "unprognostic (1.10e-2)" "unprognostic (3.56e-2)" "unprognostic (1.56e-1)" "unprognostic (2.89e-1)" "unprognostic (1.47e-1)" "unprognostic (2.72e-2)" "unprognostic (5.47e-2)" "unprognostic (2.11e-1)" "potential prognostic favorable (3.01e-4)" "unprognostic (1.96e-2)" "unprognostic (2.70e-3)" "unprognostic (5.93e-2)" "unprognostic (6.04e-2)" "unprognostic (3.19e-1)" "unprognostic (1.48e-1)" "unprognostic (1.97e-1)" "unprognostic (1.82e-1)" "unprognostic (2.98e-3)" "unprognostic (2.31e-1)" "unprognostic (9.77e-2)" "unprognostic (1.90e-1)" "unprognostic (2.21e-1)" "unprognostic (2.31e-1)" "unprognostic (3.17e-2)" "unprognostic (3.08e-1)" "unprognostic (2.17e-3)" "unprognostic (1.93e-1)" NDUFA2 B8 ENSG00000131495 "NADH:ubiquinone oxidoreductase subunit A2" O43678 5 140638740-140647771 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 613.5;Esophageal apical cells: 603.7;Parietal cells: 604.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035933 Approved Approved Mitochondria NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 97: Non-specific - Cellular respiration" 63 Mitochondria "HPA035933: " "unprognostic (8.39e-2)" "unprognostic (1.95e-1)" "unprognostic (2.24e-3)" "unprognostic (1.79e-3)" "unprognostic (7.06e-2)" "unprognostic (2.48e-2)" "unprognostic (1.26e-2)" "unprognostic (1.88e-1)" "unprognostic (1.20e-2)" "unprognostic (7.85e-2)" "unprognostic (1.37e-1)" "unprognostic (1.80e-1)" "unprognostic (1.40e-2)" "unprognostic (2.57e-1)" "unprognostic (1.07e-2)" "unprognostic (2.16e-1)" "unprognostic (1.15e-1)" "unprognostic (1.65e-1)" "unprognostic (2.26e-1)" "unprognostic (1.18e-2)" "unprognostic (2.00e-1)" "unprognostic (1.62e-2)" "unprognostic (1.69e-1)" "unprognostic (1.98e-1)" "unprognostic (1.75e-1)" "unprognostic (8.87e-3)" "unprognostic (3.12e-2)" "unprognostic (7.98e-3)" "unprognostic (3.20e-1)" "unprognostic (1.16e-1)" "unprognostic (4.17e-1)" NDUFA3 B9 ENSG00000170906 "NADH:ubiquinone oxidoreductase subunit A3" O95167 19 54102728-54109257 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 603.4" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 618.9;Late spermatids: 3263.1;Parietal cells: 1214.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" HPA046976 Supported NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 48: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 27 "HPA046976: " "unprognostic (1.30e-2)" "unprognostic (1.47e-1)" "unprognostic (7.14e-2)" "potential prognostic unfavorable (2.88e-4)" "unprognostic (6.26e-2)" "unprognostic (4.94e-3)" "unprognostic (1.36e-2)" "unprognostic (1.81e-1)" "unprognostic (1.58e-2)" "unprognostic (3.55e-2)" "unprognostic (1.00e-1)" "unprognostic (1.06e-1)" "unprognostic (2.62e-2)" "unprognostic (9.96e-3)" "unprognostic (1.35e-1)" "unprognostic (1.50e-2)" "unprognostic (1.41e-1)" "unprognostic (6.47e-2)" "unprognostic (3.98e-1)" "unprognostic (3.16e-1)" "unprognostic (4.15e-1)" "unprognostic (6.59e-2)" "unprognostic (1.31e-1)" "unprognostic (1.23e-1)" "unprognostic (6.38e-2)" "unprognostic (4.00e-1)" "unprognostic (1.60e-1)" "unprognostic (2.83e-1)" "unprognostic (4.37e-3)" "unprognostic (1.90e-1)" "unprognostic (2.89e-1)" NDUFA4 "CI-9k, COXFA4, MISTR1, MLRQ, MRCAF1" ENSG00000189043 "NDUFA4 mitochondrial complex associated" O00483 7 10931943-10940153 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 520.4;tongue: 609.4" "Cell type enhanced" "Detected in many" "Gastric progenitor cells: 2344.2;Hepatocytes: 2068.7;Parietal cells: 7487.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Colon - Smooth muscle cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078265 Approved Supported Mitochondria NA NA 14000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 52: Non-specific - Cellular respiration" "Cluster 14: Neurons - Synaptic function" "Cluster 67: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 49 Mitochondria "HPA078265: " "unprognostic (3.91e-2)" "unprognostic (3.51e-2)" "unprognostic (3.24e-1)" "unprognostic (1.06e-3)" "unprognostic (1.08e-1)" "unprognostic (1.12e-1)" "unprognostic (3.59e-2)" "unprognostic (1.60e-1)" "unprognostic (1.04e-3)" "unprognostic (8.33e-2)" "unprognostic (2.33e-1)" "unprognostic (5.51e-3)" "unprognostic (2.55e-2)" "unprognostic (3.25e-1)" "potential prognostic unfavorable (5.00e-4)" "unprognostic (1.66e-2)" "unprognostic (2.36e-1)" "unprognostic (9.41e-2)" "unprognostic (2.39e-1)" "unprognostic (1.78e-1)" "unprognostic (1.91e-3)" "potential prognostic unfavorable (9.14e-4)" "unprognostic (1.61e-1)" "unprognostic (1.54e-1)" "unprognostic (2.26e-1)" "unprognostic (5.11e-2)" "unprognostic (1.28e-1)" "unprognostic (3.61e-2)" "unprognostic (1.48e-1)" "unprognostic (2.31e-3)" "unprognostic (5.08e-2)" NDUFA4L2 "COXFA4L2, FLJ26118, MISTRH, NUOMS" ENSG00000185633 "NDUFA4 mitochondrial complex associated like 2" Q9NRX3 12 57234903-57240715 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 404.8;esophagus: 399.1" "Cell type enriched" "Detected in many" 4 "Esophageal apical cells: 6356.2" "Cell type enriched" "Detected in many" 4 "pericyte: 1113.6" "Cancer enriched" "Detected in all" 7 "Kidney Renal Clear Cell Carcinoma (TCGA): 2167.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 8 "Kidney cancer: 406.2" "Breast - Endothelial cells, Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078265 Uncertain Supported Mitochondria NA NA "Cluster 58: Skin - Keratinization" "Cluster 47: Endothelial cells - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 85: Squamous epithelial cells - Keratinization" Mitochondria "HPA078265: " "unprognostic (2.37e-1)" "unprognostic (1.53e-1)" "unprognostic (1.55e-1)" "unprognostic (1.42e-1)" "unprognostic (1.64e-2)" "unprognostic (4.83e-2)" "unprognostic (2.59e-2)" "unprognostic (2.84e-2)" "unprognostic (9.76e-3)" "unprognostic (3.88e-1)" "unprognostic (6.82e-2)" "unprognostic (1.56e-1)" "potential prognostic unfavorable (4.99e-5)" "unprognostic (1.18e-3)" "unprognostic (3.16e-2)" "unprognostic (8.19e-2)" "unprognostic (2.76e-2)" "unprognostic (8.35e-2)" "unprognostic (2.41e-1)" "unprognostic (8.53e-2)" "unprognostic (2.68e-1)" "unprognostic (1.94e-1)" "unprognostic (1.11e-1)" "unprognostic (2.25e-1)" "unprognostic (8.79e-3)" "unprognostic (2.29e-1)" "unprognostic (5.29e-2)" "unprognostic (2.12e-3)" "unprognostic (1.50e-1)" "unprognostic (1.23e-1)" "unprognostic (4.35e-2)" NDUFA5 "B13, CI-13kB, CI-13KD-B, NUFM, UQOR13" ENSG00000128609 "NADH:ubiquinone oxidoreductase subunit A5" Q16718 7 123536997-123557904 "Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 376.8" "Cell type enhanced" "Detected in all" "Parietal cells: 1025.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043175, HPA054868" Supported Approved Mitochondria NA NA 15000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 14: Neurons - Synaptic function" "Cluster 39: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 41 Mitochondria "HPA043175: , HPA054868: " "unprognostic (1.01e-1)" "unprognostic (4.38e-3)" "unprognostic (4.59e-2)" "unprognostic (1.36e-1)" "unprognostic (2.14e-1)" "unprognostic (3.22e-1)" "unprognostic (6.98e-2)" "unprognostic (3.96e-3)" "unprognostic (2.94e-1)" "unprognostic (8.98e-2)" "potential prognostic favorable (9.10e-10)" "unprognostic (7.32e-3)" "unprognostic (7.45e-3)" "unprognostic (2.64e-1)" "unprognostic (2.51e-1)" "unprognostic (2.98e-1)" "unprognostic (9.15e-2)" "unprognostic (4.57e-2)" "unprognostic (4.31e-1)" "unprognostic (4.99e-2)" "unprognostic (8.75e-2)" "unprognostic (2.21e-1)" "unprognostic (4.72e-1)" "unprognostic (1.33e-1)" "unprognostic (4.55e-2)" "unprognostic (1.82e-2)" "unprognostic (1.47e-1)" "unprognostic (3.52e-1)" "unprognostic (1.82e-1)" "unprognostic (1.28e-1)" "unprognostic (6.52e-2)" NDUFA6 "B14, CI-B14, LYRM6, NADHB14" ENSG00000184983 "NADH:ubiquinone oxidoreductase subunit A6" P56556 22 42085526-42090884 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 374.4;Esophageal apical cells: 421.2;Extravillous trophoblasts: 358.4;Hepatocytes: 466.4;Oocytes: 488.1;Parietal cells: 636.4;Platelets: 472.4;Syncytiotrophoblasts: 638.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056934 Approved "Nucleoplasm,Vesicles,Mid piece,End piece" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 66: Non-specific - Mitochondria" "Cluster 97: Non-specific - Cellular respiration" 39 "Nucleoplasm, End piece" "Vesicles, Mid piece" "HPA056934: " "unprognostic (8.46e-2)" "unprognostic (1.01e-1)" "unprognostic (2.57e-1)" "unprognostic (1.58e-1)" "unprognostic (1.40e-1)" "unprognostic (9.35e-2)" "unprognostic (1.50e-2)" "unprognostic (3.18e-1)" "unprognostic (2.43e-1)" "unprognostic (1.94e-1)" "unprognostic (1.39e-1)" "unprognostic (8.78e-2)" "unprognostic (6.23e-2)" "unprognostic (9.88e-2)" "unprognostic (4.68e-3)" "unprognostic (1.79e-2)" "unprognostic (8.10e-2)" "unprognostic (4.45e-3)" "unprognostic (7.15e-2)" "unprognostic (2.60e-1)" "unprognostic (7.31e-2)" "unprognostic (7.35e-3)" "unprognostic (5.30e-1)" "unprognostic (2.93e-1)" "unprognostic (1.73e-1)" "unprognostic (1.07e-1)" "unprognostic (3.13e-2)" "unprognostic (3.08e-1)" "unprognostic (2.47e-2)" "unprognostic (1.50e-1)" "unprognostic (2.51e-3)" NDUFA7 B14.5a ENSG00000267855 "NADH:ubiquinone oxidoreductase subunit A7" O95182 19 8308768-8321375 "Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 253.2" "Group enriched" "Detected in some" 4 "Differentiating spermatogonia: 10.2;Early primary spermatocytes: 6.0;Early spermatids: 8.0;Late primary spermatocytes: 16.7;Oocytes: 9.2;Parietal cells: 12.4" "Low cell type specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059251, HPA071866" Enhanced Approved Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 23: Non-specific - Transcription" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 58 Mitochondria "HPA059251: , HPA071866: " "unprognostic (7.09e-2)" "unprognostic (2.14e-2)" "unprognostic (9.06e-2)" "potential prognostic favorable (4.60e-4)" "unprognostic (2.86e-2)" "unprognostic (2.75e-1)" "unprognostic (9.37e-2)" "unprognostic (1.26e-2)" "unprognostic (1.30e-1)" "unprognostic (7.92e-2)" "unprognostic (1.51e-2)" "unprognostic (1.26e-1)" "unprognostic (2.44e-3)" "unprognostic (3.91e-1)" "unprognostic (1.49e-1)" "unprognostic (1.04e-1)" "unprognostic (1.77e-1)" "unprognostic (6.37e-2)" "unprognostic (2.12e-1)" "unprognostic (1.28e-2)" "unprognostic (5.31e-3)" "unprognostic (1.43e-1)" "unprognostic (1.66e-1)" "unprognostic (5.70e-2)" "unprognostic (4.41e-1)" "unprognostic (1.52e-1)" "unprognostic (8.43e-2)" "unprognostic (3.08e-1)" "unprognostic (1.63e-1)" "unprognostic (2.08e-3)" "unprognostic (1.02e-1)" NDUFA8 "MGC793, PGIV" ENSG00000119421 "NADH:ubiquinone oxidoreductase subunit A8" P51970 9 122144058-122159779 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 356.0" "Cell type enhanced" "Detected in many" "Early spermatids: 374.1;Late primary spermatocytes: 791.3;Oocytes: 400.6;Parietal cells: 355.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041510, HPA041600" Enhanced Supported "Mitochondria,Mid piece,Principal piece,End piece" NA NA 9300 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 14: Neurons - Synaptic function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 97: Non-specific - Cellular respiration" 28 Mitochondria "Mid piece, Principal piece, End piece" "HPA041510: , HPA041600: " "unprognostic (2.58e-3)" "unprognostic (1.76e-1)" "unprognostic (9.62e-2)" "unprognostic (2.37e-3)" "unprognostic (3.69e-1)" "unprognostic (1.19e-2)" "unprognostic (5.09e-1)" "unprognostic (1.56e-1)" "unprognostic (7.54e-3)" "unprognostic (1.37e-1)" "potential prognostic favorable (7.44e-5)" "unprognostic (6.46e-2)" "unprognostic (2.10e-2)" "unprognostic (1.80e-3)" "potential prognostic unfavorable (1.94e-4)" "potential prognostic unfavorable (8.26e-4)" "unprognostic (3.41e-1)" "unprognostic (1.75e-1)" "unprognostic (1.66e-1)" "unprognostic (1.95e-1)" "unprognostic (3.83e-1)" "unprognostic (3.05e-2)" "unprognostic (3.01e-3)" "unprognostic (1.03e-1)" "unprognostic (1.45e-1)" "unprognostic (2.72e-1)" "unprognostic (1.49e-1)" "unprognostic (1.46e-1)" "unprognostic (1.81e-1)" "unprognostic (1.37e-1)" "unprognostic (5.36e-2)" NDUFA9 "CI-39k, COQ11, NDUFS2L, SDR22E1" ENSG00000139180 "NADH:ubiquinone oxidoreductase subunit A9" Q16795 12 4649095-4694317 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Late spermatids: 786.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042268, HPA073212" Supported Approved Nucleoplasm,Mitochondria No No "Cluster 13: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cellular respiration" "Cluster 37: Neurons - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 114 Mitochondria Nucleoplasm "HPA042268: , HPA073212: " "unprognostic (1.02e-1)" "unprognostic (1.24e-1)" "unprognostic (5.97e-2)" "unprognostic (5.16e-3)" "unprognostic (1.57e-1)" "unprognostic (1.35e-2)" "unprognostic (2.38e-1)" "potential prognostic favorable (2.06e-4)" "unprognostic (1.35e-1)" "unprognostic (1.06e-1)" "unprognostic (8.88e-2)" "unprognostic (6.13e-2)" "potential prognostic favorable (1.94e-4)" "unprognostic (7.42e-3)" "potential prognostic unfavorable (1.03e-4)" "unprognostic (5.05e-3)" "unprognostic (7.69e-2)" "unprognostic (1.45e-2)" "unprognostic (1.62e-1)" "unprognostic (4.45e-1)" "unprognostic (1.27e-1)" "unprognostic (1.08e-1)" "unprognostic (1.79e-3)" "unprognostic (3.15e-1)" "unprognostic (1.59e-2)" "unprognostic (9.44e-2)" "unprognostic (1.65e-1)" "unprognostic (3.55e-1)" "unprognostic (1.86e-1)" "unprognostic (2.70e-1)" "unprognostic (1.71e-1)" NDUFAB1 "ACP, ACP1, FASN2A, SDAP" ENSG00000004779 "NADH:ubiquinone oxidoreductase subunit AB1" O14561 16 23581014-23596316 "Essential proteins, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 612.8" "Cell type enhanced" "Detected in all" "Esophageal basal cells: 492.7;Esophageal suprabasal cells: 491.9;Parietal cells: 666.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054364, HPA076020" Approved Supported Mitochondria No No 26000 "Cluster 13: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 54: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 60 Mitochondria "HPA054364: , HPA076020: " "unprognostic (6.81e-2)" "potential prognostic unfavorable (8.25e-5)" "unprognostic (1.68e-2)" "unprognostic (6.83e-3)" "unprognostic (1.11e-1)" "unprognostic (2.41e-2)" "unprognostic (2.53e-1)" "unprognostic (1.46e-1)" "unprognostic (1.41e-2)" "unprognostic (1.94e-1)" "unprognostic (1.50e-3)" "unprognostic (1.85e-1)" "unprognostic (6.77e-3)" "unprognostic (2.24e-2)" "unprognostic (9.91e-3)" "unprognostic (8.49e-3)" "unprognostic (5.14e-3)" "unprognostic (9.14e-2)" "unprognostic (2.83e-2)" "unprognostic (1.79e-1)" "unprognostic (9.32e-2)" "unprognostic (8.38e-2)" "unprognostic (8.97e-2)" "unprognostic (9.22e-2)" "unprognostic (2.91e-2)" "unprognostic (3.27e-1)" "unprognostic (2.13e-1)" "unprognostic (4.74e-2)" "unprognostic (2.12e-1)" "unprognostic (1.95e-1)" "unprognostic (4.09e-2)" NDUFAF1 "CGI-65, CIA30" ENSG00000137806 "NADH:ubiquinone oxidoreductase complex assembly factor 1" Q9Y375 15 41387218-41409403 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" Chaperone "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 159.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039933, HPA040064" Supported Approved Mitochondria,Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 58: Non-specific - Nuclear processes" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 56 "Mitochondria, Cytosol" "HPA039933: , HPA040064: " "unprognostic (3.82e-1)" "unprognostic (1.23e-1)" "unprognostic (3.36e-2)" "unprognostic (1.84e-2)" "unprognostic (2.89e-1)" "unprognostic (1.58e-1)" "unprognostic (2.88e-1)" "unprognostic (1.81e-1)" "potential prognostic unfavorable (7.66e-4)" "unprognostic (2.25e-2)" "potential prognostic favorable (4.39e-4)" "unprognostic (1.44e-1)" "unprognostic (1.75e-3)" "validated prognostic favorable (1.78e-4)" "validated prognostic favorable (1.98e-4)" "unprognostic (4.91e-2)" "unprognostic (3.23e-2)" "unprognostic (9.94e-2)" "unprognostic (2.30e-1)" "unprognostic (5.03e-2)" "unprognostic (4.52e-3)" "unprognostic (2.26e-1)" "unprognostic (1.27e-1)" "unprognostic (1.30e-1)" "unprognostic (3.13e-1)" "unprognostic (1.53e-2)" "unprognostic (5.89e-2)" "unprognostic (1.63e-1)" "unprognostic (1.65e-1)" "unprognostic (5.04e-2)" "unprognostic (5.05e-3)" NDUFAF2 "B17.2L, mimitin, MMTN, NDUFA12L" ENSG00000164182 "NADH:ubiquinone oxidoreductase complex assembly factor 2" Q8N183 5 60945177-61154531 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" Chaperone "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048082, HPA054776" Supported Enhanced Mitochondria NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 74: Non-specific - Signal transduction" "Cluster 1: Neurons - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 17: Non-specific - RNA processing" 21 Mitochondria "HPA048082: , HPA054776: " "unprognostic (1.06e-1)" "unprognostic (7.79e-3)" "unprognostic (6.58e-2)" "unprognostic (1.33e-1)" "unprognostic (9.71e-2)" "unprognostic (2.32e-1)" "unprognostic (4.44e-2)" "unprognostic (1.10e-1)" "unprognostic (7.65e-3)" "unprognostic (1.08e-3)" "unprognostic (1.16e-1)" "unprognostic (1.27e-1)" "potential prognostic unfavorable (1.06e-5)" "validated prognostic unfavorable (2.83e-5)" "validated prognostic unfavorable (6.25e-5)" "unprognostic (7.74e-3)" "unprognostic (1.02e-1)" "unprognostic (1.78e-1)" "unprognostic (2.62e-1)" "unprognostic (2.21e-1)" "unprognostic (1.20e-2)" "unprognostic (2.13e-1)" "unprognostic (5.68e-3)" "unprognostic (2.59e-1)" "unprognostic (1.55e-1)" "unprognostic (9.18e-2)" "unprognostic (6.69e-2)" "unprognostic (2.87e-2)" "unprognostic (2.54e-1)" "unprognostic (1.76e-1)" "unprognostic (4.71e-2)" NDUFAF3 "2P1, C3orf60, DKFZP564J0123, E3-3, MGC10527" ENSG00000178057 "NADH:ubiquinone oxidoreductase complex assembly factor 3" Q9BU61 3 49020459-49023495 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 315.3" "Cell type enhanced" "Detected in many" "Early spermatids: 1025.8;Late primary spermatocytes: 2131.7;Late spermatids: 1761.2;Megakaryocytes: 816.0;Platelets: 516.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035376, HPA035377" Enhanced NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 27: Non-specific - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 30 "HPA035376: , HPA035377: " "unprognostic (1.22e-1)" "unprognostic (1.13e-1)" "unprognostic (9.90e-2)" "unprognostic (9.30e-2)" "unprognostic (1.02e-1)" "unprognostic (2.92e-3)" "unprognostic (2.67e-2)" "unprognostic (1.73e-1)" "unprognostic (1.15e-2)" "potential prognostic unfavorable (3.92e-4)" "unprognostic (2.48e-1)" "unprognostic (8.99e-3)" "unprognostic (1.56e-2)" "unprognostic (3.83e-3)" "unprognostic (6.03e-2)" "unprognostic (2.92e-1)" "unprognostic (1.44e-2)" "unprognostic (2.02e-1)" "unprognostic (1.23e-1)" "unprognostic (4.50e-2)" "unprognostic (3.34e-2)" "unprognostic (2.26e-1)" "unprognostic (2.23e-2)" "unprognostic (2.34e-1)" "unprognostic (1.29e-1)" "unprognostic (1.35e-1)" "unprognostic (2.19e-1)" "unprognostic (3.08e-2)" "unprognostic (1.06e-1)" "unprognostic (3.59e-2)" "unprognostic (1.92e-1)" NDUFAF4 "bA22L21.1, C6orf66, HRPAP20, HSPC125, My013" ENSG00000123545 "NADH:ubiquinone oxidoreductase complex assembly factor 4" Q9P032 6 96889315-96897891 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction" Calmodulin-binding "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 248.7;Parietal cells: 122.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030216, HPA046560" Uncertain Supported Nucleoplasm,Mitochondria,Cytosol NA Yes "Cluster 43: Non-specific - Transcription & Translation" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 52 Mitochondria "Nucleoplasm, Cytosol" "HPA030216: , HPA046560: " "unprognostic (1.43e-1)" "unprognostic (2.20e-2)" "unprognostic (1.79e-1)" "unprognostic (1.15e-1)" "unprognostic (1.01e-1)" "unprognostic (2.33e-1)" "unprognostic (8.34e-2)" "unprognostic (1.10e-1)" "unprognostic (4.20e-2)" "unprognostic (5.73e-2)" "potential prognostic favorable (1.39e-4)" "unprognostic (7.01e-3)" "unprognostic (2.96e-1)" "unprognostic (4.43e-2)" "unprognostic (4.15e-3)" "unprognostic (3.54e-1)" "unprognostic (3.58e-2)" "unprognostic (5.72e-2)" "unprognostic (7.72e-2)" "unprognostic (9.20e-2)" "unprognostic (5.08e-2)" "potential prognostic favorable (2.68e-4)" "unprognostic (4.45e-2)" "unprognostic (4.61e-1)" "unprognostic (1.61e-2)" "unprognostic (1.39e-1)" "unprognostic (3.01e-1)" "unprognostic (7.21e-2)" "unprognostic (5.17e-2)" "unprognostic (1.77e-1)" "unprognostic (1.66e-1)" NDUFAF5 "C20orf7, dJ842G6.1" ENSG00000101247 "NADH:ubiquinone oxidoreductase complex assembly factor 5" Q5TEU4 20 13785007-13821580 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Methyltransferase, Oxidoreductase, Transferase" "Disease variant, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 19.2" "Cell type enhanced" "Detected in many" "Early spermatids: 99.0;Myonuclei: 108.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051184 Uncertain NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 53: Neurons - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 55: Myocytes - Oxidative muscle function" 10 "HPA051184: " "unprognostic (1.95e-1)" "unprognostic (1.11e-1)" "unprognostic (7.55e-3)" "unprognostic (2.29e-2)" "unprognostic (8.85e-2)" "unprognostic (1.25e-1)" "unprognostic (7.45e-3)" "unprognostic (2.56e-1)" "unprognostic (1.23e-1)" "potential prognostic favorable (2.40e-5)" "unprognostic (1.05e-1)" "unprognostic (1.06e-2)" "unprognostic (3.87e-2)" "unprognostic (2.22e-1)" "unprognostic (3.15e-2)" "unprognostic (2.73e-2)" "unprognostic (1.05e-1)" "unprognostic (2.12e-1)" "unprognostic (8.27e-2)" "unprognostic (3.26e-3)" "unprognostic (1.32e-2)" "unprognostic (4.27e-2)" "unprognostic (7.31e-2)" "unprognostic (1.55e-1)" "unprognostic (2.76e-1)" "unprognostic (1.78e-1)" "unprognostic (1.01e-1)" "unprognostic (2.30e-2)" "unprognostic (8.18e-2)" NDUFAF6 "C8orf38, MGC40214" ENSG00000156170 "NADH:ubiquinone oxidoreductase complex assembly factor 6" Q330K2 8 94895533-95116455 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "B-cells: 301.1;Plasma cells: 525.6;Thymocytes: 338.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047148, HPA050545" Approved NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 14: Neurons - Synaptic function" "Cluster 40: Non-specific - Unknown function" "Cluster 44: Plasma cells - Antibody production & secretion" "HPA047148: , HPA050545: " "unprognostic (1.21e-1)" "potential prognostic unfavorable (8.05e-5)" "unprognostic (2.43e-1)" "unprognostic (1.91e-1)" "unprognostic (1.65e-1)" "unprognostic (2.43e-1)" "unprognostic (9.11e-2)" "unprognostic (4.63e-2)" "potential prognostic unfavorable (5.60e-5)" "potential prognostic favorable (1.79e-4)" "unprognostic (8.16e-3)" "unprognostic (2.31e-2)" "unprognostic (4.82e-2)" "unprognostic (3.37e-2)" "unprognostic (2.44e-2)" "unprognostic (3.67e-1)" "unprognostic (4.77e-1)" "unprognostic (5.16e-2)" "unprognostic (1.12e-1)" "unprognostic (9.00e-2)" "unprognostic (5.04e-3)" "unprognostic (1.12e-2)" "unprognostic (2.44e-2)" "unprognostic (1.04e-2)" "unprognostic (1.33e-1)" "unprognostic (4.83e-2)" "unprognostic (2.07e-1)" "unprognostic (3.19e-1)" "unprognostic (3.27e-2)" NDUFAF7 "C2orf56, MidA, PRO1853" ENSG00000003509 "NADH:ubiquinone oxidoreductase complex assembly factor 7" Q7L592 2 37231631-37253403 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 36.2" "Cell type enhanced" "Detected in many" "Early spermatids: 176.3;Late primary spermatocytes: 310.1;Late spermatids: 142.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045217 Uncertain NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 39: Testis - Nuclear processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 8 "HPA045217: " "unprognostic (1.09e-1)" "unprognostic (2.79e-2)" "unprognostic (1.08e-1)" "unprognostic (1.14e-1)" "unprognostic (3.74e-2)" "unprognostic (1.08e-1)" "unprognostic (2.38e-3)" "unprognostic (2.64e-1)" "unprognostic (2.09e-2)" "unprognostic (6.00e-3)" "unprognostic (3.26e-2)" "unprognostic (8.73e-2)" "potential prognostic unfavorable (5.12e-5)" "unprognostic (2.51e-1)" "unprognostic (1.11e-1)" "unprognostic (6.15e-2)" "unprognostic (3.22e-2)" "unprognostic (1.13e-1)" "unprognostic (2.20e-1)" "unprognostic (2.99e-1)" "unprognostic (1.83e-2)" "unprognostic (1.67e-2)" "unprognostic (1.41e-2)" "unprognostic (9.03e-3)" "unprognostic (3.47e-1)" "unprognostic (1.11e-2)" "unprognostic (2.27e-1)" "unprognostic (2.24e-1)" "unprognostic (2.07e-1)" NDUFAF8 C17orf89 ENSG00000224877 "NADH:ubiquinone oxidoreductase complex assembly factor 8" A1L188 17 81239305-81241310 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 276.5;Hepatocytes: 305.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057732 Uncertain Supported Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Ribosome" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 97: Non-specific - Cellular respiration" 3 Mitochondria "HPA057732: " "unprognostic (2.14e-1)" "unprognostic (6.29e-2)" "unprognostic (3.78e-2)" "unprognostic (1.27e-1)" "unprognostic (3.25e-1)" "unprognostic (7.38e-2)" "unprognostic (2.88e-1)" "unprognostic (6.26e-3)" "unprognostic (6.02e-3)" "potential prognostic unfavorable (4.05e-5)" "unprognostic (1.46e-3)" "unprognostic (1.14e-1)" "unprognostic (6.26e-2)" "unprognostic (1.31e-1)" "unprognostic (5.51e-2)" "unprognostic (6.93e-2)" "unprognostic (5.65e-3)" "unprognostic (2.34e-2)" "unprognostic (1.07e-1)" "unprognostic (6.43e-3)" "unprognostic (3.52e-1)" "unprognostic (2.57e-1)" "unprognostic (6.04e-2)" "unprognostic (8.40e-2)" "unprognostic (6.98e-3)" "unprognostic (1.07e-1)" "unprognostic (1.06e-1)" "unprognostic (2.38e-1)" "unprognostic (3.47e-1)" NDUFB1 "CI-MNLL, MNLL" ENSG00000183648 "NADH:ubiquinone oxidoreductase subunit B1" O75438 14 92116122-92121917 "Essential proteins, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric chief cells: 896.6;Hepatocytes: 1858.1;Parietal cells: 2816.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063737 Supported Supported "Nuclear speckles,Mitochondria" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 97: Non-specific - Cellular respiration" 9 Mitochondria "Nuclear speckles" "HPA063737: " "unprognostic (6.48e-2)" "unprognostic (3.25e-2)" "unprognostic (3.87e-2)" "potential prognostic favorable (1.32e-5)" "unprognostic (1.67e-2)" "unprognostic (2.35e-2)" "unprognostic (3.45e-1)" "unprognostic (2.36e-3)" "unprognostic (4.25e-2)" "unprognostic (3.77e-2)" "unprognostic (2.16e-1)" "unprognostic (2.20e-1)" "unprognostic (3.28e-2)" "unprognostic (1.35e-1)" "unprognostic (1.53e-1)" "unprognostic (6.48e-3)" "unprognostic (1.71e-2)" "unprognostic (6.56e-3)" "unprognostic (1.47e-1)" "unprognostic (6.68e-3)" "unprognostic (6.85e-2)" "unprognostic (2.30e-2)" "unprognostic (3.22e-1)" "unprognostic (2.56e-1)" "unprognostic (4.19e-2)" "unprognostic (3.45e-3)" "potential prognostic unfavorable (8.21e-4)" "unprognostic (5.33e-2)" "unprognostic (2.30e-1)" "unprognostic (2.58e-1)" "unprognostic (2.70e-2)" NDUFB10 PDSW ENSG00000140990 "NADH:ubiquinone oxidoreductase subunit B10" O96000 16 1959538-1961975 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "heart muscle: 755.8;skeletal muscle: 1217.5;tongue: 945.6" "Cell type enhanced" "Detected in all" "Enterocytes: 788.9;Late spermatids: 1469.2;Parietal cells: 974.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073189 Supported NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 14: Neurons - Synaptic function" "Cluster 54: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 56 "HPA073189: " "unprognostic (2.23e-1)" "unprognostic (9.77e-2)" "unprognostic (1.62e-1)" "unprognostic (3.63e-2)" "unprognostic (7.72e-2)" "unprognostic (1.34e-1)" "unprognostic (3.13e-1)" "unprognostic (3.36e-2)" "unprognostic (7.45e-2)" "unprognostic (6.15e-2)" "unprognostic (3.73e-2)" "unprognostic (1.24e-1)" "unprognostic (3.75e-3)" "unprognostic (3.46e-1)" "unprognostic (1.66e-2)" "unprognostic (5.79e-2)" "unprognostic (1.15e-2)" "unprognostic (5.99e-2)" "unprognostic (1.91e-1)" "unprognostic (7.78e-2)" "unprognostic (4.68e-1)" "unprognostic (1.70e-1)" "unprognostic (4.45e-2)" "unprognostic (1.19e-1)" "unprognostic (1.79e-1)" "unprognostic (2.81e-1)" "unprognostic (1.25e-1)" "unprognostic (4.14e-2)" "unprognostic (3.38e-1)" "unprognostic (5.16e-2)" "unprognostic (2.48e-1)" NDUFB11 "ESSS, Np15, NP17.3" ENSG00000147123 "NADH:ubiquinone oxidoreductase subunit B11" Q9NX14 X 47142071-47145466 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Cardiomyopathy, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 661.3" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 1352.4;Hepatocytes: 762.1;Parietal cells: 972.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030367 Supported Supported "Mitochondria,Acrosome,Equatorial segment,Connecting piece,Mid piece,Principal piece" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 36: Non-specific - mRNA processing" "Cluster 84: Apical squamous epithelium - Cornification" 40 Mitochondria "Acrosome, Equatorial segment, Connecting piece, Mid piece, Principal piece" "HPA030367: " "unprognostic (1.27e-1)" "unprognostic (2.96e-2)" "unprognostic (1.97e-1)" "unprognostic (6.33e-3)" "unprognostic (1.83e-1)" "unprognostic (3.14e-2)" "unprognostic (4.14e-1)" "unprognostic (1.18e-2)" "unprognostic (1.21e-1)" "unprognostic (4.69e-2)" "unprognostic (1.37e-2)" "unprognostic (1.16e-2)" "unprognostic (2.43e-2)" "unprognostic (4.16e-3)" "potential prognostic unfavorable (4.69e-4)" "unprognostic (5.67e-2)" "unprognostic (2.15e-1)" "unprognostic (6.42e-2)" "unprognostic (1.82e-1)" "unprognostic (1.42e-2)" "unprognostic (5.29e-2)" "unprognostic (8.82e-3)" "unprognostic (1.93e-1)" "unprognostic (2.67e-1)" "unprognostic (2.90e-1)" "unprognostic (2.44e-1)" "unprognostic (3.37e-1)" "unprognostic (7.67e-2)" "unprognostic (1.70e-1)" "unprognostic (1.34e-1)" "unprognostic (3.27e-2)" NDUFB2 "AGGG, CI-AGGG" ENSG00000090266 "NADH:ubiquinone oxidoreductase subunit B2" O95178 7 140690777-140722790 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 1116.6;Hepatocytes: 1216.3;Parietal cells: 1419.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051377 Approved Uncertain Nucleoplasm,Mitochondria NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 39: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 1 Nucleoplasm Mitochondria "HPA051377: " "unprognostic (1.85e-1)" "unprognostic (3.69e-1)" "unprognostic (2.38e-1)" "unprognostic (5.55e-2)" "unprognostic (2.46e-2)" "unprognostic (3.75e-3)" "potential prognostic unfavorable (3.65e-6)" "unprognostic (4.26e-2)" "unprognostic (1.39e-1)" "unprognostic (1.20e-3)" "unprognostic (2.67e-3)" "unprognostic (1.47e-2)" "potential prognostic favorable (1.86e-4)" "unprognostic (3.78e-3)" "potential prognostic unfavorable (5.94e-4)" "unprognostic (4.48e-2)" "unprognostic (9.30e-2)" "unprognostic (3.09e-2)" "unprognostic (4.33e-2)" "unprognostic (4.09e-2)" "unprognostic (2.40e-1)" "potential prognostic favorable (1.91e-4)" "unprognostic (3.48e-2)" "unprognostic (9.66e-2)" "unprognostic (1.05e-1)" "unprognostic (1.36e-1)" "unprognostic (1.97e-1)" "unprognostic (1.93e-2)" "unprognostic (2.47e-1)" "unprognostic (5.79e-2)" "unprognostic (1.03e-1)" NDUFB3 B12 ENSG00000119013 "NADH:ubiquinone oxidoreductase subunit B3" O43676 2 201071433-201085750 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 659.2;tongue: 676.6" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 767.7;Esophageal suprabasal cells: 596.4;Late primary spermatocytes: 487.3;Parietal cells: 739.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034596 Enhanced NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 97: Non-specific - Cellular respiration" 83 "HPA034596: " "unprognostic (7.60e-2)" "potential prognostic unfavorable (8.73e-4)" "unprognostic (1.75e-2)" "unprognostic (2.63e-1)" "unprognostic (3.14e-1)" "unprognostic (3.12e-3)" "potential prognostic unfavorable (4.15e-4)" "unprognostic (9.42e-2)" "potential prognostic unfavorable (9.30e-4)" "potential prognostic unfavorable (2.35e-4)" "potential prognostic favorable (3.00e-4)" "unprognostic (1.40e-1)" "unprognostic (2.47e-1)" "validated prognostic unfavorable (1.52e-4)" "validated prognostic unfavorable (5.50e-7)" "unprognostic (1.23e-3)" "unprognostic (4.03e-1)" "unprognostic (4.40e-2)" "unprognostic (2.65e-1)" "unprognostic (2.11e-2)" "unprognostic (9.94e-2)" "unprognostic (2.10e-2)" "unprognostic (2.72e-1)" "unprognostic (5.46e-2)" "unprognostic (1.84e-1)" "unprognostic (1.63e-1)" "unprognostic (3.97e-2)" "unprognostic (1.20e-1)" "unprognostic (9.60e-2)" "unprognostic (1.08e-1)" "unprognostic (6.36e-2)" NDUFB4 B15 ENSG00000065518 "NADH:ubiquinone oxidoreductase subunit B4" O95168 3 120596328-120602507 "Essential proteins, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 887.5" "Cell type enhanced" "Detected in many" "Early spermatids: 955.0;Esophageal apical cells: 940.3;Late primary spermatocytes: 1280.0;Parietal cells: 1127.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051739, HPA064441" Enhanced Approved "Nucleoplasm,Nuclear membrane,Mitochondria,Principal piece" No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 97: Non-specific - Cellular respiration" 25 Mitochondria "Nucleoplasm, Nuclear membrane, Principal piece" "HPA051739: , HPA064441: " "unprognostic (2.12e-1)" "unprognostic (4.60e-2)" "unprognostic (2.52e-2)" "potential prognostic favorable (4.81e-4)" "unprognostic (5.10e-3)" "unprognostic (5.94e-2)" "unprognostic (1.89e-1)" "unprognostic (9.76e-2)" "unprognostic (1.90e-1)" "unprognostic (1.20e-2)" "unprognostic (1.20e-1)" "unprognostic (2.23e-2)" "unprognostic (2.29e-1)" "unprognostic (1.91e-3)" "unprognostic (4.80e-3)" "potential prognostic unfavorable (3.70e-4)" "unprognostic (5.63e-2)" "unprognostic (3.04e-1)" "unprognostic (2.96e-1)" "potential prognostic favorable (9.06e-4)" "unprognostic (5.59e-2)" "potential prognostic unfavorable (3.86e-4)" "unprognostic (1.89e-1)" "unprognostic (2.88e-1)" "unprognostic (3.42e-1)" "unprognostic (9.58e-3)" "unprognostic (2.96e-1)" "unprognostic (3.00e-2)" "unprognostic (1.91e-1)" "unprognostic (7.68e-2)" "unprognostic (3.85e-2)" NDUFB5 "CI-SGDH, MGC12314, SGDH" ENSG00000136521 "NADH:ubiquinone oxidoreductase subunit B5" O43674 3 179604690-179627647 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 226.3" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 59.9;Early spermatids: 80.0;Late primary spermatocytes: 188.7;Parietal cells: 61.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005640 Enhanced Supported Nucleoplasm,Mitochondria NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 52: Non-specific - Cellular respiration" "Cluster 23: Choroid plexus - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 98: Neurons - Neurotransmission & signaling" 81 Mitochondria Nucleoplasm "HPA005640: " "unprognostic (4.21e-1)" "unprognostic (2.65e-1)" "unprognostic (1.93e-1)" "unprognostic (1.50e-2)" "unprognostic (3.52e-1)" "unprognostic (1.98e-1)" "unprognostic (1.16e-1)" "unprognostic (7.87e-3)" "unprognostic (1.08e-3)" "unprognostic (1.00e-2)" "potential prognostic favorable (6.49e-6)" "unprognostic (5.80e-2)" "unprognostic (6.76e-3)" "unprognostic (3.72e-1)" "potential prognostic unfavorable (5.86e-5)" "unprognostic (1.56e-2)" "unprognostic (8.60e-2)" "unprognostic (8.48e-2)" "unprognostic (5.52e-3)" "unprognostic (5.58e-2)" "unprognostic (2.32e-3)" "unprognostic (2.11e-2)" "unprognostic (1.63e-1)" "unprognostic (4.45e-2)" "potential prognostic favorable (5.61e-4)" "unprognostic (8.26e-2)" "unprognostic (4.92e-3)" "unprognostic (2.02e-1)" "unprognostic (1.77e-1)" "unprognostic (1.42e-1)" "unprognostic (1.32e-1)" NDUFB6 "B17, CI" ENSG00000165264 "NADH:ubiquinone oxidoreductase subunit B6" O95139 9 32553001-32573184 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 1080.7;Late primary spermatocytes: 689.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044001, HPA053334" Supported Approved Nucleoplasm,Mitochondria No No "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 27: Non-specific - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 28 Mitochondria Nucleoplasm "HPA044001: , HPA053334: " "unprognostic (1.39e-1)" "unprognostic (2.78e-1)" "unprognostic (1.99e-3)" "unprognostic (4.64e-2)" "unprognostic (1.29e-1)" "unprognostic (1.16e-1)" "unprognostic (5.74e-1)" "unprognostic (2.08e-1)" "unprognostic (4.42e-2)" "unprognostic (1.37e-2)" "potential prognostic favorable (1.20e-11)" "unprognostic (9.10e-2)" "potential prognostic favorable (8.83e-5)" "unprognostic (9.13e-2)" "unprognostic (2.49e-2)" "unprognostic (2.95e-2)" "unprognostic (3.90e-2)" "unprognostic (6.28e-2)" "unprognostic (1.01e-1)" "unprognostic (2.84e-3)" "unprognostic (8.61e-2)" "unprognostic (2.06e-1)" "unprognostic (8.33e-2)" "unprognostic (8.02e-2)" "unprognostic (5.05e-2)" "unprognostic (1.61e-1)" "unprognostic (5.99e-3)" "unprognostic (3.91e-1)" "unprognostic (1.64e-1)" "unprognostic (2.23e-1)" "unprognostic (2.33e-1)" NDUFB7 "B18, CI-B18, MGC2480" ENSG00000099795 "NADH:ubiquinone oxidoreductase subunit B7" P17568 19 14566078-14572066 "Essential proteins, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 1005.9;Enterocytes: 802.9;Parietal cells: 1023.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002817 Enhanced NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 45: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 54 "HPA002817: " "unprognostic (3.90e-1)" "unprognostic (2.54e-1)" "unprognostic (1.49e-2)" "potential prognostic favorable (1.16e-4)" "unprognostic (2.06e-2)" "unprognostic (1.54e-1)" "unprognostic (2.35e-1)" "unprognostic (3.25e-1)" "unprognostic (1.71e-1)" "unprognostic (5.37e-3)" "unprognostic (1.35e-2)" "unprognostic (3.35e-1)" "unprognostic (2.31e-2)" "unprognostic (1.20e-1)" "unprognostic (2.90e-2)" "unprognostic (8.35e-3)" "unprognostic (1.75e-1)" "unprognostic (1.11e-1)" "unprognostic (1.63e-1)" "unprognostic (4.74e-2)" "unprognostic (7.21e-2)" "unprognostic (6.05e-3)" "unprognostic (3.41e-2)" "unprognostic (5.87e-2)" "unprognostic (1.87e-1)" "unprognostic (5.55e-2)" "unprognostic (8.84e-2)" "unprognostic (1.94e-1)" "unprognostic (6.02e-2)" "unprognostic (3.47e-1)" "unprognostic (1.59e-1)" NDUFB8 "ASHI, CI-ASHI" ENSG00000166136 "NADH:ubiquinone oxidoreductase subunit B8" O95169 10 100523740-100530000 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Parietal cells: 647.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003886, HPA065549" Supported Enhanced Mitochondria NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 52: Non-specific - Cellular respiration" "Cluster 14: Neurons - Synaptic function" "Cluster 52: Non-specific - Mitochondria" "Cluster 97: Non-specific - Cellular respiration" 28 Mitochondria "HPA003886: , HPA065549: " "unprognostic (8.20e-3)" "unprognostic (4.00e-2)" "potential prognostic favorable (5.85e-4)" "unprognostic (2.04e-2)" "unprognostic (4.74e-1)" "unprognostic (1.48e-2)" "unprognostic (1.56e-1)" "potential prognostic favorable (1.05e-6)" "unprognostic (1.78e-2)" "unprognostic (9.94e-2)" "potential prognostic favorable (1.49e-6)" "unprognostic (3.55e-2)" "potential prognostic favorable (6.63e-4)" "unprognostic (1.39e-1)" "unprognostic (2.18e-1)" "unprognostic (5.85e-2)" "unprognostic (1.27e-1)" "unprognostic (2.25e-1)" "unprognostic (2.40e-1)" "unprognostic (2.39e-1)" "unprognostic (5.33e-2)" "unprognostic (4.78e-2)" "unprognostic (2.13e-1)" "unprognostic (3.18e-1)" "unprognostic (3.67e-2)" "unprognostic (1.01e-1)" "unprognostic (3.59e-3)" "unprognostic (2.18e-1)" "unprognostic (2.45e-2)" "unprognostic (3.98e-2)" "unprognostic (9.31e-2)" NDUFB9 "B22, LYRM3, UQOR22" ENSG00000147684 "NADH:ubiquinone oxidoreductase subunit B9" Q9Y6M9 8 124539101-124580648 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 1286.6;tongue: 1386.4" "Cell type enhanced" "Detected in all" "Esophageal basal cells: 813.4;Esophageal suprabasal cells: 779.5;Gastric progenitor cells: 1027.9;Late spermatids: 1280.7;Parietal cells: 1002.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042768 Approved Supported Mitochondria NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 45: Non-specific - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 55 Mitochondria "HPA042768: " "unprognostic (2.20e-1)" "unprognostic (4.21e-3)" "unprognostic (2.29e-1)" "unprognostic (8.08e-2)" "unprognostic (3.24e-1)" "unprognostic (4.56e-3)" "unprognostic (3.80e-1)" "unprognostic (1.56e-3)" "unprognostic (2.03e-2)" "unprognostic (1.20e-2)" "unprognostic (1.08e-1)" "unprognostic (1.79e-1)" "unprognostic (1.54e-2)" "unprognostic (1.23e-1)" "unprognostic (3.19e-3)" "unprognostic (3.90e-2)" "unprognostic (4.26e-2)" "unprognostic (2.68e-1)" "unprognostic (7.03e-2)" "unprognostic (2.58e-1)" "unprognostic (1.63e-1)" "unprognostic (2.19e-2)" "unprognostic (6.86e-2)" "unprognostic (2.85e-1)" "unprognostic (2.31e-1)" "unprognostic (1.05e-1)" "unprognostic (2.34e-1)" "unprognostic (2.22e-1)" "unprognostic (1.17e-1)" "unprognostic (1.33e-1)" "unprognostic (2.16e-1)" NDUFC1 KFYI ENSG00000109390 "NADH:ubiquinone oxidoreductase subunit C1" O43677 4 139266880-139302551 "Metabolic proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "heart muscle: 78.4;skeletal muscle: 251.3;tongue: 148.5" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 966.0;Parietal cells: 857.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044556, HPA062427" Enhanced Supported Mitochondria No No "Cluster 46: Basophils - Proteolysis" "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 55: Non-specific - Transcription" "Cluster 66: Non-specific - Mitochondria" "Cluster 97: Non-specific - Cellular respiration" Mitochondria "HPA044556: , HPA062427: " "unprognostic (4.07e-2)" "unprognostic (1.39e-2)" "unprognostic (4.81e-3)" "unprognostic (3.14e-2)" "unprognostic (8.18e-3)" "unprognostic (3.03e-1)" "unprognostic (5.58e-3)" "unprognostic (7.52e-2)" "unprognostic (9.97e-2)" "unprognostic (5.06e-3)" "potential prognostic favorable (3.17e-4)" "unprognostic (5.65e-3)" "potential prognostic favorable (9.51e-5)" "unprognostic (1.08e-2)" "unprognostic (1.57e-1)" "unprognostic (9.62e-2)" "unprognostic (6.70e-2)" "unprognostic (2.28e-1)" "unprognostic (1.48e-2)" "unprognostic (3.36e-1)" "unprognostic (4.05e-1)" "unprognostic (1.30e-3)" "unprognostic (1.41e-1)" "unprognostic (7.21e-2)" "unprognostic (2.23e-1)" "unprognostic (1.29e-1)" "unprognostic (4.48e-2)" "unprognostic (2.07e-1)" "unprognostic (1.91e-1)" "unprognostic (4.75e-2)" "unprognostic (1.26e-1)" NDUFC2 "B14.5b, HLC-1" ENSG00000151366 "NADH:ubiquinone oxidoreductase subunit C2" O95298 11 78068297-78079862 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric progenitor cells: 539.6;Hepatocytes: 756.6;Late primary spermatocytes: 549.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Skin - Sebaceous gland cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038873, HPA056195" Approved Approved Mitochondria NA NA 18000 "Cluster 22: Eosinophils - Transcription" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 24: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 42 Mitochondria "HPA038873: , HPA056195: " "unprognostic (6.63e-2)" "unprognostic (4.93e-3)" "unprognostic (3.45e-1)" "unprognostic (1.73e-1)" "unprognostic (1.77e-1)" "unprognostic (1.42e-1)" "unprognostic (2.66e-1)" "unprognostic (2.93e-2)" "unprognostic (3.16e-2)" "unprognostic (1.12e-3)" "potential prognostic favorable (9.52e-4)" "unprognostic (1.66e-1)" "unprognostic (4.57e-2)" "unprognostic (1.37e-1)" "unprognostic (3.22e-3)" "unprognostic (2.45e-3)" "unprognostic (1.18e-2)" "unprognostic (1.06e-1)" "unprognostic (2.61e-1)" "potential prognostic favorable (2.67e-4)" "unprognostic (4.28e-2)" "unprognostic (2.60e-2)" "unprognostic (3.16e-1)" "unprognostic (7.49e-2)" "unprognostic (1.77e-3)" "unprognostic (7.67e-2)" "unprognostic (4.33e-2)" "unprognostic (6.37e-2)" "unprognostic (1.93e-1)" "unprognostic (1.36e-3)" "unprognostic (1.97e-1)" NDUFC2-KCTD14 ENSG00000259112 "NDUFC2-KCTD14 readthrough" E9PQ53 11 78016971-78079865 "Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 16 "Adipocytes: 179.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA038873, HPA056195" Approved Approved Mitochondria NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 52: Non-specific - Cellular respiration" "Cluster 29: Forebrain - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 89: Adipocytes - Lipid metabolism" Mitochondria "HPA038873: , HPA056195: " "unprognostic (9.68e-2)" "unprognostic (5.39e-2)" "unprognostic (2.66e-1)" "unprognostic (9.34e-3)" "unprognostic (1.57e-1)" "unprognostic (1.15e-1)" "unprognostic (2.75e-1)" "unprognostic (3.86e-3)" "potential prognostic favorable (1.77e-4)" "unprognostic (1.54e-1)" "unprognostic (7.30e-2)" "unprognostic (4.82e-1)" "unprognostic (3.68e-2)" "unprognostic (7.02e-2)" "unprognostic (2.13e-1)" "unprognostic (1.34e-1)" "unprognostic (2.73e-2)" "unprognostic (7.06e-3)" "unprognostic (2.26e-1)" "unprognostic (3.02e-2)" "unprognostic (1.43e-3)" "unprognostic (1.97e-1)" "unprognostic (8.00e-2)" "unprognostic (5.76e-2)" "unprognostic (1.39e-1)" "unprognostic (3.14e-2)" "unprognostic (1.62e-1)" NDUFS1 CI-75k ENSG00000023228 "NADH:ubiquinone oxidoreductase core subunit S1" P28331 2 206114817-206159509 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Oxidoreductase, Translocase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 170.1;skeletal muscle: 210.5;tongue: 210.3" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 113.3;Brain inhibitory neurons: 122.2;Choroid plexus epithelial cells: 234.2;Distal convoluted tubule cells: 139.3;Loop of henle epithelial cells: 96.2;Oligodendrocyte progenitor cells: 91.9;Oligodendrocytes: 91.2;Other brain neurons: 101.3;Proximal tubule cells: 95.8;Renal collecting duct intercalated cells: 119.5;Renal connecting tubule cells: 101.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064605, CAB070844" Enhanced Supported Mitochondria NA NA 44000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 52: Non-specific - Cellular respiration" "Cluster 23: Choroid plexus - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 102: Non-specific - Mixed function" 71 Mitochondria "CAB070844: , HPA064605: " "unprognostic (2.05e-1)" "potential prognostic unfavorable (9.66e-4)" "unprognostic (2.85e-1)" "unprognostic (1.66e-1)" "unprognostic (2.74e-2)" "unprognostic (3.44e-2)" "unprognostic (2.52e-1)" "unprognostic (1.64e-2)" "unprognostic (1.38e-1)" "unprognostic (3.22e-2)" "potential prognostic favorable (2.12e-9)" "unprognostic (1.32e-2)" "unprognostic (1.12e-2)" "unprognostic (3.87e-3)" "unprognostic (6.54e-2)" "unprognostic (5.33e-3)" "unprognostic (1.75e-1)" "unprognostic (4.65e-2)" "unprognostic (1.19e-1)" "unprognostic (1.86e-1)" "unprognostic (2.77e-1)" "unprognostic (1.38e-2)" "unprognostic (1.13e-1)" "unprognostic (2.72e-2)" "unprognostic (5.01e-1)" "unprognostic (3.12e-2)" "unprognostic (1.70e-3)" "unprognostic (1.44e-1)" "unprognostic (1.64e-1)" "unprognostic (7.84e-2)" "unprognostic (2.90e-1)" NDUFS2 CI-49 ENSG00000158864 "NADH:ubiquinone oxidoreductase core subunit S2" O75306 1 161197104-161214723 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Oxidoreductase, Translocase" "Disease variant, Leber hereditary optic neuropathy, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 435.2;tongue: 591.6" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Minor Salivary Gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055140, HPA061953" Enhanced Approved "Mitochondria,Calyx,Connecting piece" NA NA 37000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 45: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 68 Mitochondria "Calyx, Connecting piece" "HPA055140: , HPA061953: " "unprognostic (5.07e-3)" "unprognostic (1.61e-2)" "unprognostic (3.03e-1)" "unprognostic (2.77e-2)" "unprognostic (4.89e-3)" "unprognostic (1.40e-2)" "unprognostic (2.34e-1)" "potential prognostic favorable (5.35e-5)" "unprognostic (2.37e-1)" "unprognostic (7.41e-3)" "potential prognostic favorable (3.63e-8)" "unprognostic (3.41e-3)" "unprognostic (6.29e-3)" "unprognostic (1.12e-2)" "unprognostic (1.48e-1)" "unprognostic (6.28e-3)" "unprognostic (1.35e-2)" "unprognostic (4.12e-1)" "unprognostic (3.79e-2)" "unprognostic (4.08e-1)" "unprognostic (3.20e-1)" "unprognostic (9.60e-2)" "unprognostic (9.23e-2)" "unprognostic (9.06e-2)" "unprognostic (1.90e-1)" "unprognostic (6.72e-3)" "unprognostic (1.15e-1)" "unprognostic (1.66e-1)" "unprognostic (1.43e-1)" "unprognostic (2.09e-2)" "unprognostic (1.25e-1)" NDUFS3 CI-30 ENSG00000213619 "NADH:ubiquinone oxidoreductase core subunit S3" O75489 11 47565336-47584562 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Oxidoreductase, Translocase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 318.8" "Cell type enhanced" "Detected in many" "Hofbauer cells: 175.6;Oocytes: 179.6;Parietal cells: 343.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004484, CAB034894" Enhanced Supported "Nuclear bodies,Mitochondria,Principal piece" NA NA 13000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 24: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 114 Mitochondria "Nuclear bodies, Principal piece" "CAB034894: , HPA004484: " "unprognostic (1.02e-1)" "unprognostic (9.44e-2)" "unprognostic (5.59e-2)" "unprognostic (2.89e-2)" "unprognostic (9.27e-2)" "unprognostic (1.37e-3)" "unprognostic (1.66e-1)" "unprognostic (3.09e-2)" "unprognostic (7.34e-2)" "unprognostic (7.60e-3)" "potential prognostic favorable (9.43e-5)" "unprognostic (1.60e-2)" "unprognostic (1.80e-3)" "validated prognostic unfavorable (6.05e-4)" "validated prognostic unfavorable (4.92e-4)" "unprognostic (4.43e-2)" "potential prognostic unfavorable (6.58e-4)" "unprognostic (2.40e-2)" "unprognostic (3.51e-1)" "unprognostic (2.93e-2)" "unprognostic (2.86e-1)" "unprognostic (1.89e-2)" "unprognostic (3.32e-1)" "unprognostic (6.67e-2)" "unprognostic (3.90e-2)" "unprognostic (1.59e-1)" "unprognostic (2.21e-1)" "unprognostic (4.77e-2)" "unprognostic (1.90e-1)" "unprognostic (3.94e-2)" "unprognostic (4.29e-1)" NDUFS4 "AQDQ, CI-18" ENSG00000164258 "NADH:ubiquinone oxidoreductase subunit S4" O43181 5 53560633-53683338 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003884 Supported Supported "Mitochondria,Equatorial segment,Perinuclear theca,Calyx" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cellular respiration" "Cluster 27: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 97: Non-specific - Cellular respiration" 48 Mitochondria "Equatorial segment, Perinuclear theca, Calyx" "HPA003884: " "unprognostic (1.00e-1)" "unprognostic (1.77e-2)" "potential prognostic unfavorable (1.37e-4)" "potential prognostic favorable (5.22e-6)" "unprognostic (5.55e-2)" "unprognostic (1.24e-1)" "unprognostic (1.03e-1)" "unprognostic (3.27e-1)" "potential prognostic unfavorable (1.16e-4)" "unprognostic (3.09e-2)" "potential prognostic favorable (4.30e-10)" "unprognostic (1.55e-2)" "unprognostic (4.80e-3)" "unprognostic (1.61e-1)" "unprognostic (1.92e-2)" "unprognostic (7.65e-2)" "unprognostic (8.14e-2)" "unprognostic (1.02e-1)" "unprognostic (2.27e-1)" "unprognostic (9.07e-2)" "unprognostic (2.03e-2)" "unprognostic (6.92e-2)" "potential prognostic unfavorable (3.45e-4)" "unprognostic (5.39e-2)" "unprognostic (4.70e-2)" "unprognostic (2.80e-2)" "unprognostic (3.17e-1)" "unprognostic (5.23e-3)" "unprognostic (8.01e-2)" "unprognostic (1.36e-1)" "unprognostic (2.98e-1)" NDUFS5 CI-15k ENSG00000168653 "NADH:ubiquinone oxidoreductase subunit S5" O43920 1 39026318-39034636 "Essential proteins, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal suprabasal cells: 1254.5;Megakaryocytes: 1446.5;Parietal cells: 1394.9;Platelets: 1273.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042582 Supported NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 14: Neurons - Synaptic function" "Cluster 37: Non-specific - mRNA processing" "Cluster 97: Non-specific - Cellular respiration" 71 "HPA042582: " "unprognostic (3.10e-1)" "unprognostic (2.91e-2)" "unprognostic (3.09e-1)" "unprognostic (4.39e-2)" "unprognostic (6.71e-2)" "unprognostic (1.34e-1)" "unprognostic (6.28e-2)" "unprognostic (1.97e-2)" "unprognostic (3.17e-2)" "unprognostic (5.45e-2)" "unprognostic (3.07e-1)" "unprognostic (3.28e-1)" "unprognostic (8.41e-3)" "potential prognostic unfavorable (4.75e-4)" "unprognostic (6.66e-3)" "unprognostic (1.24e-1)" "unprognostic (1.62e-3)" "unprognostic (7.39e-2)" "unprognostic (2.81e-1)" "potential prognostic favorable (6.34e-4)" "unprognostic (2.68e-1)" "unprognostic (5.05e-2)" "unprognostic (3.97e-1)" "unprognostic (1.23e-1)" "unprognostic (5.93e-2)" "unprognostic (2.59e-2)" "unprognostic (3.68e-1)" "unprognostic (3.44e-2)" "unprognostic (1.65e-1)" "unprognostic (2.50e-3)" "unprognostic (1.31e-1)" NDUFS6 CI-13kA ENSG00000145494 "NADH:ubiquinone oxidoreductase subunit S6" O75380 5 1801407-1816048 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 577.0" "Cell type enhanced" "Detected in all" "Esophageal suprabasal cells: 739.2;Parietal cells: 689.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064221 Supported NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 29: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 89 "HPA064221: " "unprognostic (1.55e-1)" "unprognostic (1.55e-2)" "unprognostic (1.00e-1)" "unprognostic (9.13e-2)" "unprognostic (2.81e-1)" "unprognostic (1.16e-1)" "unprognostic (1.41e-2)" "unprognostic (1.99e-1)" "unprognostic (2.19e-1)" "potential prognostic unfavorable (1.08e-4)" "unprognostic (4.20e-2)" "unprognostic (6.60e-2)" "unprognostic (9.81e-2)" "unprognostic (2.55e-3)" "potential prognostic unfavorable (1.41e-4)" "unprognostic (1.13e-2)" "unprognostic (1.38e-2)" "unprognostic (1.55e-1)" "unprognostic (3.28e-1)" "unprognostic (3.28e-2)" "unprognostic (1.34e-2)" "unprognostic (5.96e-3)" "unprognostic (8.95e-3)" "unprognostic (1.63e-1)" "unprognostic (2.56e-1)" "unprognostic (3.13e-2)" "unprognostic (1.35e-1)" "unprognostic (5.57e-2)" "unprognostic (2.64e-1)" "unprognostic (9.03e-2)" "unprognostic (1.43e-1)" NDUFS7 "CI-20, FLJ45860, FLJ46880, PSST" ENSG00000115286 "NADH:ubiquinone oxidoreductase core subunit S7" O75251 19 1383527-1395589 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Oxidoreductase, Translocase" "Disease variant, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 623.2" "Cell type enhanced" "Detected in all" "Enterocytes: 528.0;Esophageal basal cells: 515.1;Esophageal suprabasal cells: 651.5;Late primary spermatocytes: 538.1;Late spermatids: 591.1;Parietal cells: 661.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 9700 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 136 "unprognostic (6.37e-3)" "unprognostic (3.14e-2)" "unprognostic (6.59e-3)" "potential prognostic favorable (6.63e-4)" "unprognostic (8.66e-2)" "unprognostic (4.37e-2)" "unprognostic (3.59e-1)" "unprognostic (1.90e-3)" "unprognostic (1.08e-1)" "unprognostic (1.54e-1)" "unprognostic (4.74e-3)" "unprognostic (3.20e-1)" "potential prognostic favorable (3.00e-4)" "unprognostic (1.26e-2)" "unprognostic (5.69e-2)" "unprognostic (1.90e-1)" "unprognostic (1.89e-1)" "unprognostic (1.23e-1)" "unprognostic (3.16e-1)" "unprognostic (2.25e-1)" "unprognostic (7.09e-2)" "unprognostic (3.11e-3)" "unprognostic (9.50e-2)" "unprognostic (1.27e-1)" "unprognostic (1.36e-1)" "unprognostic (2.61e-1)" "unprognostic (8.73e-3)" "unprognostic (4.89e-1)" "unprognostic (8.25e-2)" "unprognostic (8.92e-2)" "unprognostic (4.49e-1)" NDUFS8 "CI-23k, TYKY" ENSG00000110717 "NADH:ubiquinone oxidoreductase core subunit S8" O00217 11 68030617-68036644 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Oxidoreductase, Translocase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal suprabasal cells: 498.3;Late spermatids: 1355.2;Parietal cells: 792.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018524, HPA067429" Enhanced Approved Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 24: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 63 Mitochondria "HPA018524: , HPA067429: " "potential prognostic unfavorable (4.16e-4)" "unprognostic (2.75e-1)" "unprognostic (4.39e-1)" "potential prognostic favorable (6.94e-4)" "unprognostic (1.03e-1)" "unprognostic (7.09e-2)" "unprognostic (1.95e-1)" "unprognostic (7.69e-2)" "unprognostic (1.94e-3)" "unprognostic (1.97e-1)" "unprognostic (3.74e-3)" "unprognostic (1.12e-2)" "potential prognostic favorable (6.22e-6)" "unprognostic (1.16e-2)" "unprognostic (4.85e-2)" "unprognostic (2.14e-2)" "unprognostic (1.30e-1)" "unprognostic (2.99e-2)" "unprognostic (1.78e-1)" "unprognostic (2.54e-2)" "unprognostic (4.78e-2)" "unprognostic (1.27e-1)" "unprognostic (1.92e-2)" "unprognostic (1.83e-1)" "unprognostic (3.12e-1)" "unprognostic (8.77e-2)" "unprognostic (6.20e-2)" "unprognostic (2.17e-1)" "unprognostic (5.47e-2)" "unprognostic (1.27e-1)" "unprognostic (3.58e-2)" NDUFV1 CI-51K ENSG00000167792 "NADH:ubiquinone oxidoreductase core subunit V1" P49821 11 67605653-67612554 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Oxidoreductase, Translocase" "Disease variant, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Parietal cells: 465.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Minor Salivary Gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045211, HPA075051" Enhanced Approved Mitochondria,Cytosol No No 87000 "Cluster 13: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cellular respiration" "Cluster 45: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 64 Mitochondria Cytosol "HPA045211: , HPA075051: " "potential prognostic unfavorable (1.10e-4)" "unprognostic (1.48e-2)" "unprognostic (7.39e-2)" "unprognostic (1.23e-1)" "unprognostic (4.66e-2)" "unprognostic (4.13e-2)" "unprognostic (1.31e-1)" "unprognostic (4.87e-3)" "unprognostic (8.90e-3)" "unprognostic (1.88e-2)" "potential prognostic favorable (1.15e-8)" "unprognostic (1.89e-1)" "potential prognostic favorable (6.64e-5)" "unprognostic (4.96e-2)" "unprognostic (1.36e-1)" "unprognostic (7.35e-2)" "unprognostic (4.81e-2)" "unprognostic (1.21e-1)" "unprognostic (1.31e-1)" "unprognostic (4.39e-1)" "unprognostic (5.79e-2)" "unprognostic (1.12e-1)" "unprognostic (1.20e-1)" "unprognostic (2.40e-2)" "unprognostic (3.18e-2)" "unprognostic (3.87e-2)" "unprognostic (3.22e-1)" "unprognostic (3.79e-2)" "unprognostic (1.05e-1)" "unprognostic (2.19e-1)" "unprognostic (8.87e-2)" NDUFV2 CI-24k ENSG00000178127 "NADH:ubiquinone oxidoreductase core subunit V2" P19404 18 9102630-9134345 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Oxidoreductase, Translocase" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 133.9;Enteric stem cells: 115.1;Enteric transient amplifying cells: 147.5;Enterocytes: 173.1;Epididymal basal cells: 113.1;Epididymal clear cells: 122.5;Epididymal efferent duct ciliated cells: 122.1;Epididymal principal cells: 94.1;Gastric chief cells: 88.5;Goblet cells: 87.5;Paneth cells: 108.3;Parietal cells: 244.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003404, HPA077896" Enhanced Approved Nucleoplasm,Mitochondria,Cytosol No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 45: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 15: Non-specific - Protein processing" 110 Mitochondria "Nucleoplasm, Cytosol" "HPA003404: , HPA077896: " "unprognostic (1.06e-2)" "unprognostic (4.92e-1)" "unprognostic (2.31e-1)" "unprognostic (7.99e-3)" "unprognostic (1.28e-1)" "unprognostic (1.48e-1)" "unprognostic (7.46e-3)" "unprognostic (1.51e-3)" "potential prognostic unfavorable (3.36e-4)" "unprognostic (5.98e-2)" "unprognostic (7.95e-3)" "unprognostic (2.22e-2)" "unprognostic (3.51e-2)" "unprognostic (1.55e-1)" "unprognostic (4.91e-2)" "unprognostic (3.42e-2)" "unprognostic (9.68e-2)" "unprognostic (2.11e-1)" "unprognostic (8.07e-2)" "unprognostic (2.95e-3)" "unprognostic (4.03e-1)" "unprognostic (1.22e-1)" "unprognostic (8.32e-2)" "unprognostic (4.88e-2)" "unprognostic (4.72e-2)" "unprognostic (3.12e-1)" "unprognostic (9.02e-2)" "unprognostic (4.03e-1)" "unprognostic (2.35e-1)" "unprognostic (5.88e-2)" "unprognostic (1.78e-1)" NDUFV3 CI-10k ENSG00000160194 "NADH:ubiquinone oxidoreductase subunit V3" P56181 21 42879644-42913304 "FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 30.8" "Cell type enriched" "Detected in all" 4 "Late spermatids: 2576.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019791, HPA020463, HPA030427, CAB034142" Enhanced Enhanced Mitochondria NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 52: Non-specific - Cellular respiration" "Cluster 6: Non-specific - Immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 28 Mitochondria "CAB034142: , HPA019791: , HPA020463: , HPA030427: " "unprognostic (4.69e-3)" "unprognostic (3.43e-2)" "unprognostic (2.55e-1)" "unprognostic (3.04e-2)" "unprognostic (1.01e-1)" "unprognostic (5.04e-3)" "unprognostic (3.50e-1)" "unprognostic (4.02e-1)" "unprognostic (8.32e-2)" "unprognostic (3.35e-2)" "unprognostic (8.75e-2)" "unprognostic (4.52e-3)" "unprognostic (1.56e-2)" "unprognostic (3.29e-1)" "unprognostic (3.14e-1)" "unprognostic (2.69e-1)" "unprognostic (3.73e-3)" "unprognostic (9.91e-2)" "unprognostic (2.91e-2)" "unprognostic (1.82e-1)" "unprognostic (1.02e-3)" "unprognostic (1.28e-3)" "unprognostic (2.68e-1)" "unprognostic (4.55e-1)" "unprognostic (3.33e-2)" "unprognostic (1.62e-1)" "unprognostic (1.01e-1)" "unprognostic (1.05e-1)" "potential prognostic favorable (6.73e-4)" "unprognostic (1.73e-1)" "unprognostic (3.97e-2)" NEB "NEB177D, NEM2" ENSG00000183091 Nebulin P20929 2 151485336-151734487 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Muscle protein" "Cancer-related genes, Disease variant, Nemaline myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 71 "skeletal muscle: 7182.0;tongue: 2198.5" "Group enriched" "Detected in many" 49 "Myonuclei: 22433.1;Thymic myoid cells: 7044.2" "Cell type enhanced" "Detected in all" "ependymal cell: 70.0" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 36.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 9.6" "Group enriched" "Detected in some" 6 "cerebellum: 6.5;olfactory bulb: 4.0" "Region enriched" "Detected in some" 6 "cerebellum: 15.8" HPA016601 Enhanced NA NA 86000 "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 15: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 21 "HPA016601: " "unprognostic (8.12e-2)" "unprognostic (7.73e-2)" "unprognostic (2.07e-2)" "unprognostic (2.54e-2)" "unprognostic (1.43e-1)" "unprognostic (1.70e-1)" "unprognostic (1.83e-1)" "unprognostic (1.89e-1)" "unprognostic (2.73e-3)" "potential prognostic unfavorable (9.98e-5)" "unprognostic (1.41e-3)" "potential prognostic unfavorable (7.26e-4)" "unprognostic (2.25e-2)" "unprognostic (1.33e-3)" "unprognostic (2.94e-1)" "unprognostic (2.03e-2)" "unprognostic (6.71e-3)" "unprognostic (6.29e-2)" "unprognostic (1.19e-1)" "unprognostic (2.17e-2)" "unprognostic (6.85e-2)" "unprognostic (5.06e-2)" "unprognostic (1.41e-1)" "unprognostic (1.07e-1)" "unprognostic (5.25e-2)" "unprognostic (1.98e-1)" "unprognostic (3.79e-2)" "unprognostic (3.81e-3)" "unprognostic (8.64e-2)" NEBL "bA165O3.1, C10orf113, LASP2, LNEBL" ENSG00000078114 Nebulette O76041 10 20779973-21293011 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 15 "heart muscle: 292.1" "Cell type enhanced" "Detected in many" "Astrocytes: 1700.5;Cardiomyocytes: 3558.9;Ependymal cells: 1682.0;Podocytes: 4258.9;Retinal horizontal cells: 1474.5;Salivary acinar cells: 1532.5;Salivary ionocytes: 1416.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 10.1" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 1, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013994, HPA013995" Approved NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 44: Non-specific - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 33 "HPA013994: , HPA013995: " "unprognostic (1.14e-2)" "unprognostic (1.50e-1)" "unprognostic (1.62e-1)" "unprognostic (8.77e-3)" "unprognostic (2.01e-1)" "unprognostic (1.56e-1)" "unprognostic (2.48e-2)" "unprognostic (1.36e-1)" "unprognostic (7.89e-2)" "unprognostic (1.44e-1)" "validated prognostic favorable (2.15e-6)" "validated prognostic favorable (1.28e-4)" "unprognostic (1.98e-2)" "unprognostic (2.11e-3)" "unprognostic (1.66e-1)" "unprognostic (6.58e-2)" "unprognostic (7.42e-3)" "unprognostic (2.63e-1)" "unprognostic (1.44e-2)" "unprognostic (9.63e-2)" "unprognostic (2.43e-1)" "unprognostic (2.16e-3)" "unprognostic (9.58e-2)" "unprognostic (3.13e-2)" "unprognostic (9.30e-2)" "unprognostic (1.20e-1)" NECAB1 EFCBP1 ENSG00000123119 "N-terminal EF-hand calcium binding protein 1" Q8N987 8 90791741-90959393 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 49.7;choroid plexus: 15.9" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 127.6;Alveolar cells type 2: 145.5;Brain excitatory neurons: 208.5;Brain inhibitory neurons: 250.6;Cardiomyocytes: 354.2;Choroid plexus epithelial cells: 566.3;Epicardial cells: 213.8;Neutrophils: 214.9;Oligodendrocytes: 360.7;Other brain neurons: 152.5;Pituicytes/FSCs: 267.9;Podocytes: 454.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 5.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Lung - Alveolar cells type 2, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023252, HPA023629, HPA025963, HPA031262, CAB068208, CAB068209, CAB068210" Enhanced Supported Supported "Nucleoplasm,Mitotic spindle,Primary cilium,Primary cilium tip,Cytosol" Yes NA "Cluster 78: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 35: Neurons - Synaptic function & neurogenesis" 11 Nucleoplasm "Mitotic spindle, Primary cilium, Primary cilium tip, Cytosol" "CAB068208: , CAB068209: , CAB068210: , HPA023252: , HPA023629: , HPA025963: , HPA031262: " "unprognostic (1.63e-1)" "unprognostic (2.27e-1)" "unprognostic (1.17e-1)" "unprognostic (2.78e-1)" "unprognostic (1.56e-3)" "potential prognostic favorable (9.16e-4)" "potential prognostic favorable (6.45e-4)" "unprognostic (1.14e-1)" "unprognostic (2.04e-2)" "unprognostic (9.58e-3)" "unprognostic (1.85e-3)" "unprognostic (6.72e-3)" "unprognostic (7.31e-2)" NECAB2 EFCBP2 ENSG00000103154 "N-terminal EF-hand calcium binding protein 2" Q7Z6G3 16 83968244-84002776 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 137.0" "Cell type enhanced" "Detected in some" "Brain inhibitory neurons: 35.8;Early spermatids: 14.0;Hepatocytes: 22.6;Late primary spermatocytes: 11.8;Late spermatids: 82.4;Müller glia: 12.7;Neutrophils: 20.4;Oocytes: 27.6;Other brain neurons: 40.8;Pancreatic islet cells: 16.9;Pituitary stem cells: 17.2" "Cell type enhanced" "Detected in many" "CGE interneuron: 89.7" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 19.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 66 "neutrophil: 55.8" "Lineage enriched" "Detected in single" 66 "granulocytes: 55.8" "Low cancer specificity" "Detected in many" "Colon - Colon enteroendocrine cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Pancreas - Alpha cells, Spleen - Neutrophils_2, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" "HPA013998, HPA014144, CAB068211" Enhanced Supported NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 35: Neurons - Synaptic function & neurogenesis" 12 "CAB068211: , HPA013998: , HPA014144: " "unprognostic (2.68e-3)" "unprognostic (8.60e-2)" "unprognostic (1.52e-1)" "unprognostic (2.20e-2)" "unprognostic (3.83e-1)" "unprognostic (1.20e-2)" "unprognostic (1.49e-1)" "unprognostic (3.63e-2)" "unprognostic (6.33e-2)" "potential prognostic favorable (6.52e-7)" "unprognostic (4.30e-3)" "unprognostic (1.14e-1)" "potential prognostic favorable (6.30e-4)" "unprognostic (3.49e-2)" "unprognostic (1.42e-1)" "unprognostic (9.80e-2)" "unprognostic (4.28e-2)" NECAB3 "APBA2BP, dJ63M2.4, dJ63M2.5, EFCBP3, NIP1, SYTIP2, XB51" ENSG00000125967 "N-terminal EF-hand calcium binding protein 3" Q96P71 20 33657087-33674463 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 101.0;Late primary spermatocytes: 72.9;Late spermatids: 74.3;Oocytes: 59.9;Parietal cells: 70.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044785, HPA070595, HPA071786" Supported Supported "Golgi apparatus" "Intracellular and membrane" "No annotated function" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 7: Liver cancer - Metabolism" "Cluster 98: Neurons - Neurotransmission & signaling" 2 "Golgi apparatus" "HPA044785: , HPA070595: , HPA071786: " "unprognostic (2.51e-1)" "unprognostic (7.80e-2)" "unprognostic (2.63e-1)" "unprognostic (1.36e-1)" "unprognostic (4.95e-2)" "unprognostic (1.07e-1)" "unprognostic (2.33e-1)" "unprognostic (7.87e-3)" "unprognostic (2.06e-1)" "unprognostic (5.26e-2)" "unprognostic (1.20e-1)" "unprognostic (4.13e-3)" "unprognostic (2.72e-1)" "unprognostic (6.59e-2)" "unprognostic (2.66e-2)" "unprognostic (1.15e-2)" "unprognostic (1.20e-1)" "unprognostic (1.06e-2)" "unprognostic (1.62e-2)" "unprognostic (1.34e-1)" "unprognostic (2.46e-3)" "unprognostic (3.96e-3)" "unprognostic (2.50e-1)" "unprognostic (3.52e-1)" "unprognostic (4.27e-2)" "unprognostic (1.19e-1)" "unprognostic (2.34e-2)" "unprognostic (5.56e-2)" "unprognostic (7.69e-2)" "unprognostic (1.91e-1)" "unprognostic (6.83e-2)" NECAP1 DKFZP566B183 ENSG00000089818 "NECAP endocytosis associated 1" Q8NC96 12 8076939-8097881 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" Epilepsy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 64.7" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 18.8;Distal convoluted tubule cells: 14.6;Early spermatids: 7.6;Late spermatids: 9.6;Loop of henle epithelial cells: 11.8;Papillary tip epithelial cells: 9.3;Podocytes: 15.5;Proximal tubule cells: 8.4;Renal collecting duct intercalated cells: 13.3;Renal collecting duct principal cells: 9.6;Renal connecting tubule cells: 13.2" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053980, HPA063300" Uncertain Approved Vesicles,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 27: Cerebellum - Synaptic function" "Cluster 14: Neurons - Synaptic function" "Cluster 38: Non-specific - Transcription" "Cluster 105: Non-specific - Mixed function" 33 Vesicles Cytosol "HPA053980: , HPA063300: " "unprognostic (9.64e-2)" "potential prognostic unfavorable (2.77e-4)" "unprognostic (1.31e-1)" "unprognostic (1.56e-2)" "unprognostic (5.06e-2)" "potential prognostic unfavorable (4.29e-4)" "unprognostic (1.67e-1)" "unprognostic (2.10e-2)" "unprognostic (2.36e-3)" "potential prognostic unfavorable (9.72e-5)" "validated prognostic favorable (6.63e-8)" "validated prognostic favorable (4.33e-4)" "unprognostic (8.65e-2)" "unprognostic (7.08e-2)" "unprognostic (6.24e-2)" "unprognostic (1.09e-1)" "unprognostic (2.31e-1)" "unprognostic (4.66e-2)" "unprognostic (6.01e-2)" "unprognostic (5.06e-3)" "unprognostic (3.47e-1)" "unprognostic (3.01e-1)" "unprognostic (5.24e-3)" "unprognostic (2.24e-1)" "unprognostic (3.25e-3)" "unprognostic (8.09e-2)" "unprognostic (6.32e-2)" "unprognostic (1.62e-1)" "unprognostic (1.78e-1)" "unprognostic (1.06e-1)" "unprognostic (7.77e-2)" NECAP2 FLJ10420 ENSG00000157191 "NECAP endocytosis associated 2" Q9NVZ3 1 16440721-16460078 "Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 153.8;Hofbauer cells: 188.8;Kupffer cells: 167.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028077 Approved Approved "Endoplasmic reticulum" No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 39: Astrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 26 "Endoplasmic reticulum" "HPA028077: " "unprognostic (3.03e-2)" "unprognostic (6.83e-2)" "unprognostic (1.05e-2)" "unprognostic (4.71e-2)" "unprognostic (1.04e-1)" "unprognostic (1.41e-1)" "unprognostic (1.85e-1)" "unprognostic (1.88e-1)" "unprognostic (8.95e-2)" "unprognostic (5.31e-2)" "validated prognostic favorable (3.43e-6)" "validated prognostic favorable (8.50e-4)" "unprognostic (3.08e-1)" "potential prognostic unfavorable (1.67e-5)" "unprognostic (1.04e-2)" "unprognostic (7.10e-2)" "unprognostic (1.66e-3)" "unprognostic (3.18e-2)" "unprognostic (2.20e-2)" "unprognostic (8.49e-2)" "unprognostic (2.54e-1)" "unprognostic (1.88e-1)" "unprognostic (2.03e-2)" "unprognostic (1.63e-1)" "unprognostic (1.87e-1)" "unprognostic (9.82e-3)" "unprognostic (1.21e-1)" "unprognostic (2.54e-1)" "unprognostic (2.24e-1)" "unprognostic (2.93e-1)" "unprognostic (9.68e-3)" NECTIN1 "CD111, CLPED1, ED4, HIgR, HVEC, Nectin-1, OFC7, PRR, PRR1, PVRL1, PVRR1, SK-12" ENSG00000110400 "Nectin cell adhesion molecule 1" Q15223 11 119623408-119729200 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 121.1;skin 1: 126.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 114.5;Esophageal apical cells: 260.8;Esophageal basal cells: 180.7;Esophageal suprabasal cells: 294.1;Ocular epithelial cells: 173.3;Prostatic hillock cells: 203.1;Retinal bipolar cells: 177.2;Suprabasal keratinocytes: 208.1;Urothelial cells: 213.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.6" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 131.1" "Breast - Breast myoepithelial cells, Minor Salivary Gland - Minor salivary gland basal cells, Pituitary gland - Gonadotropes, Skin - Keratinocyte (granular), Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016135, HPA026846" Approved "Secreted in other tissues" Receptor NA NA 6600000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 10 "CAB016135: , HPA026846: " "unprognostic (3.83e-1)" "unprognostic (2.91e-1)" "unprognostic (2.65e-2)" "unprognostic (1.88e-2)" "unprognostic (1.60e-1)" "unprognostic (1.14e-1)" "unprognostic (5.91e-2)" "unprognostic (1.80e-1)" "unprognostic (2.78e-3)" "unprognostic (5.28e-2)" "potential prognostic favorable (3.83e-4)" "unprognostic (1.31e-1)" "unprognostic (1.10e-3)" "unprognostic (2.25e-2)" "unprognostic (3.95e-2)" "unprognostic (1.63e-1)" "unprognostic (8.65e-2)" "unprognostic (1.18e-1)" "unprognostic (2.05e-1)" "unprognostic (5.23e-2)" "unprognostic (2.51e-3)" "unprognostic (9.80e-2)" "unprognostic (2.87e-2)" "unprognostic (3.74e-1)" "unprognostic (5.82e-3)" "unprognostic (9.13e-3)" "unprognostic (1.71e-1)" "unprognostic (1.14e-1)" "unprognostic (4.45e-3)" NECTIN2 "CD112, HVEB, Nectin-2, PRR2, PVRL2, PVRR2" ENSG00000130202 "Nectin cell adhesion molecule 2" Q92692 19 44846175-44889223 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 597.7" "Cell type enhanced" "Detected in many" "endothelial cell: 130.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 10.4" "Lineage enhanced" "Detected in many" "granulocytes: 10.4" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Colon - Endothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012374, HPA012759, CAB026138" Enhanced Approved "Vesicles,Plasma membrane,Mitotic spindle" Yes Yes 4300000 "Cluster 19: Eosinophils - Unknown function" "Cluster 28: Liver & Adrenal gland - Secretion" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 66: Non-specific - Mitochondria" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 26 Vesicles "Plasma membrane, Mitotic spindle" "CAB026138: , HPA012374: , HPA012759: " "unprognostic (1.21e-2)" "unprognostic (1.20e-2)" "unprognostic (1.38e-1)" "unprognostic (2.14e-2)" "unprognostic (1.32e-1)" "unprognostic (1.38e-2)" "unprognostic (1.40e-2)" "unprognostic (2.34e-2)" "unprognostic (2.73e-1)" "unprognostic (1.66e-2)" "unprognostic (2.91e-1)" "unprognostic (2.11e-1)" "unprognostic (1.68e-2)" "unprognostic (3.38e-3)" "unprognostic (1.79e-1)" "unprognostic (3.05e-1)" "unprognostic (1.13e-1)" "unprognostic (2.50e-1)" "unprognostic (3.60e-2)" "unprognostic (1.72e-1)" "unprognostic (8.19e-2)" "unprognostic (2.91e-1)" "unprognostic (1.49e-1)" "unprognostic (1.52e-1)" "unprognostic (1.40e-1)" "unprognostic (2.85e-1)" "unprognostic (2.00e-1)" "unprognostic (3.25e-1)" "unprognostic (1.39e-1)" NECTIN3 "CD113, CDw113, DKFZP566B0846, nectin-3, PPR3, PVRL3, PVRR3" ENSG00000177707 "Nectin cell adhesion molecule 3" Q9NQS3 3 111070071-111275563 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 51.0" "Cell type enhanced" "Detected in many" "Early spermatids: 315.4;Late spermatids: 392.1;Mucous neck cells: 266.9;Oligodendrocyte progenitor cells: 241.4;Sertoli cells: 317.0;Syncytiotrophoblasts: 348.2" "Cell type enhanced" "Detected in many" "hippocampal CA4: 355.0;upper-layer intratelencephalic: 345.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Spleen - Fibroblasts_1, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009869, HPA011038" Approved Uncertain "Cell Junctions,Cytosol" NA NA 3500000 "Cluster 21: Testis - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 24 "Cell Junctions, Cytosol" "CAB009869: , HPA011038: " "unprognostic (6.40e-2)" "unprognostic (2.89e-1)" "unprognostic (1.98e-3)" "unprognostic (1.57e-2)" "unprognostic (4.67e-2)" "unprognostic (1.12e-1)" "unprognostic (4.36e-2)" "unprognostic (2.91e-1)" "unprognostic (8.18e-3)" "potential prognostic favorable (2.94e-8)" "unprognostic (4.02e-3)" "unprognostic (1.10e-1)" "unprognostic (5.57e-2)" "unprognostic (1.96e-1)" "unprognostic (1.51e-1)" "unprognostic (1.25e-1)" "unprognostic (1.22e-1)" "unprognostic (1.43e-1)" "unprognostic (1.13e-2)" "unprognostic (1.90e-2)" "unprognostic (1.09e-1)" "unprognostic (1.06e-1)" "unprognostic (6.64e-2)" "unprognostic (1.08e-2)" "unprognostic (7.66e-2)" "unprognostic (2.56e-1)" "unprognostic (1.12e-1)" "unprognostic (1.51e-1)" "unprognostic (9.33e-2)" NECTIN4 "LNIR, nectin-4, PRR4, PVRL4" ENSG00000143217 "Nectin cell adhesion molecule 4" Q96NY8 1 161070998-161089558 "Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "cervix: 40.7;esophagus: 96.0;salivary gland: 32.2;skin 1: 110.2;vagina: 56.4" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 743.5;Esophageal suprabasal cells: 312.2;Extravillous trophoblasts: 115.1;Ocular epithelial cells: 247.1;Prostatic hillock cells: 174.2;Suprabasal keratinocytes: 233.0;Syncytiotrophoblasts: 571.5;Urothelial cells: 241.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 112.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 27.9" "Lung - Alveolar cells type 2, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA010775 Enhanced Supported "Plasma membrane" "Secreted in other tissues" Receptor No No 2300000 "Cluster 22: Eosinophils - Transcription" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 6 "Plasma membrane" "HPA010775: " "unprognostic (1.86e-1)" "potential prognostic unfavorable (3.01e-4)" "unprognostic (4.27e-1)" "unprognostic (1.77e-1)" "unprognostic (9.91e-2)" "unprognostic (8.36e-2)" "unprognostic (1.83e-1)" "unprognostic (1.55e-2)" "unprognostic (1.01e-1)" "unprognostic (1.35e-3)" "unprognostic (1.44e-1)" "unprognostic (2.56e-1)" "unprognostic (1.92e-1)" "unprognostic (2.21e-2)" "unprognostic (1.17e-2)" "unprognostic (3.19e-1)" "unprognostic (2.24e-2)" "unprognostic (3.37e-2)" "unprognostic (2.62e-2)" "unprognostic (4.56e-3)" "unprognostic (5.30e-2)" "unprognostic (2.90e-1)" "unprognostic (2.79e-2)" "unprognostic (1.02e-1)" NEDD1 "GCP-WD, TUBGCP7" ENSG00000139350 "NEDD1 gamma-tubulin ring complex targeting factor" Q8NHV4 12 96907224-96953780 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 235.9;Late primary spermatocytes: 254.1;Late spermatids: 131.4;Neutrophil progenitors: 116.1" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 75.2;ependymal cell: 85.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Skeletal myocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038591 Approved Approved Nucleoplasm,Centrosome NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 46: Brainstem - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 69 "Nucleoplasm, Centrosome" "HPA038591: " "unprognostic (2.85e-1)" "unprognostic (5.49e-2)" "unprognostic (3.52e-1)" "unprognostic (4.58e-2)" "unprognostic (3.22e-2)" "unprognostic (2.77e-1)" "unprognostic (1.56e-1)" "unprognostic (6.38e-2)" "unprognostic (5.81e-2)" "potential prognostic unfavorable (9.11e-4)" "potential prognostic favorable (1.14e-5)" "unprognostic (2.46e-2)" "unprognostic (2.23e-1)" "potential prognostic unfavorable (2.27e-4)" "unprognostic (2.65e-3)" "potential prognostic unfavorable (1.52e-5)" "unprognostic (3.46e-2)" "unprognostic (1.64e-1)" "unprognostic (2.14e-1)" "unprognostic (1.20e-2)" "unprognostic (3.35e-3)" "unprognostic (1.52e-2)" "potential prognostic unfavorable (8.86e-4)" "unprognostic (3.25e-2)" "unprognostic (3.58e-2)" "unprognostic (2.92e-2)" "unprognostic (1.57e-1)" "unprognostic (2.88e-1)" "unprognostic (4.11e-1)" "unprognostic (6.90e-2)" "unprognostic (1.09e-2)" NEDD4 "KIAA0093, MGC176705, NEDD4-1, RPF1" ENSG00000069869 "NEDD4 E3 ubiquitin protein ligase" P46934 15 55826922-55993660 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, Neurogenesis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 63.3;tongue: 54.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 178.2;Enterocytes: 266.0;Hematopoietic stem cells: 180.0;Myonuclei: 524.7;Neutrophil progenitors: 219.6" "Cell type enhanced" "Detected in many" "endothelial cell: 219.3;oligodendrocyte precursor cell: 138.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Lung - Endothelial cells, Minor Salivary Gland - Endothelial cells, Pituitary gland - Endothelial cells, Spleen - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001991, HPA039883, HPA046793, CAB072833" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 63: Non-specific - Basic cellular processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 214 "Nucleoplasm, Cytosol" "Plasma membrane" "CAB001991: , CAB072833: , HPA039883: , HPA046793: " "unprognostic (3.71e-2)" "unprognostic (1.16e-1)" "unprognostic (3.12e-1)" "unprognostic (3.36e-2)" "unprognostic (6.96e-2)" "unprognostic (3.83e-1)" "unprognostic (3.69e-2)" "unprognostic (5.41e-2)" "unprognostic (3.40e-1)" "unprognostic (2.40e-2)" "potential prognostic favorable (7.82e-4)" "unprognostic (4.78e-2)" "unprognostic (5.75e-2)" "unprognostic (4.65e-3)" "unprognostic (1.48e-2)" "potential prognostic unfavorable (3.36e-5)" "unprognostic (1.55e-2)" "unprognostic (2.10e-1)" "unprognostic (2.20e-2)" "unprognostic (2.56e-2)" "unprognostic (7.76e-2)" "unprognostic (2.82e-2)" "unprognostic (6.80e-3)" "unprognostic (2.88e-1)" "unprognostic (1.57e-1)" "unprognostic (6.95e-2)" "unprognostic (4.03e-2)" "unprognostic (1.29e-2)" "unprognostic (3.70e-1)" "unprognostic (1.28e-1)" NEDD4L "KIAA0439, NEDD4-2, RSP5" ENSG00000049759 "NEDD4 like E3 ubiquitin protein ligase" Q96PU5 18 58044226-58401540 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Differentiation, Host-virus interaction, Ubl conjugation pathway" Transferase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 2267.3;Colonocytes: 1863.6;Cone photoreceptor cells: 1890.0;Prostatic glandular cells: 2827.6;Renal collecting duct intercalated cells: 2574.7;Somatotrophs: 1793.0;Transitional alveolar cells: 2573.1;Urothelial cells: 2503.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "T-reg: 5.1" "Lineage enriched" "Detected in many" 4 "T-cells: 5.1" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Somatotropes, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024618 Approved NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 60: Stomach - Digestion" "Cluster 33: Neurons - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 113 "HPA024618: " "unprognostic (3.54e-1)" "unprognostic (7.13e-2)" "unprognostic (1.15e-1)" "unprognostic (1.74e-1)" "unprognostic (4.00e-2)" "unprognostic (7.60e-2)" "unprognostic (1.25e-1)" "unprognostic (1.85e-1)" "unprognostic (2.92e-1)" "unprognostic (9.19e-2)" "potential prognostic favorable (1.60e-7)" "unprognostic (1.11e-3)" "potential prognostic favorable (2.69e-5)" "unprognostic (4.63e-3)" "potential prognostic unfavorable (6.67e-4)" "potential prognostic favorable (8.93e-4)" "unprognostic (6.22e-2)" "unprognostic (3.95e-1)" "unprognostic (1.03e-3)" "unprognostic (1.67e-1)" "unprognostic (3.31e-1)" "unprognostic (1.59e-1)" "unprognostic (7.82e-3)" "unprognostic (4.34e-2)" "unprognostic (4.04e-3)" "unprognostic (3.62e-2)" "unprognostic (3.52e-2)" "unprognostic (2.74e-1)" "unprognostic (1.08e-1)" "unprognostic (1.35e-1)" "unprognostic (1.54e-1)" NEDD8 Nedd-8 ENSG00000129559 "NEDD8 ubiquitin like modifier" Q15843 14 24216857-24232367 "Cancer-related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric chief cells: 150.7;Parietal cells: 182.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004082, HPA027583, HPA060254" Uncertain Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 1100000 "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 97: Non-specific - Cellular respiration" 100 Nucleoplasm "Golgi apparatus, Cytosol" "CAB004082: , HPA027583: , HPA060254: " "unprognostic (1.62e-1)" "unprognostic (5.37e-2)" "unprognostic (3.71e-2)" "unprognostic (9.34e-3)" "unprognostic (3.33e-2)" "unprognostic (1.40e-1)" "unprognostic (3.43e-1)" "unprognostic (6.98e-2)" "potential prognostic unfavorable (1.45e-4)" "potential prognostic unfavorable (3.91e-4)" "potential prognostic favorable (5.90e-6)" "unprognostic (3.86e-2)" "unprognostic (1.72e-1)" "unprognostic (7.68e-3)" "potential prognostic unfavorable (2.01e-4)" "unprognostic (7.97e-3)" "unprognostic (7.12e-3)" "unprognostic (1.48e-2)" "unprognostic (2.43e-1)" "unprognostic (1.34e-1)" "unprognostic (2.69e-1)" "unprognostic (7.68e-2)" "unprognostic (6.57e-2)" "unprognostic (2.72e-1)" "unprognostic (1.91e-2)" "unprognostic (2.02e-2)" "unprognostic (2.55e-1)" "unprognostic (1.27e-2)" "unprognostic (1.44e-1)" "unprognostic (1.36e-1)" "unprognostic (2.73e-1)" NEDD8-MDP1 ENSG00000255526 "NEDD8-MDP1 readthrough" 14 24213955-24232352 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skeletal muscle: 1.2;testis: 1.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in single" 6 "cerebral cortex: 1.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "HPA003064, HPA060254" Uncertain Approved Nucleoplasm NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 9 Nucleoplasm "HPA003064: , HPA060254: " "unprognostic (8.15e-2)" "unprognostic (1.67e-1)" "unprognostic (5.36e-1)" "unprognostic (2.61e-1)" "unprognostic (6.70e-1)" NEDD9 "CAS-L, CASS2, HEF1" ENSG00000111859 "Neural precursor cell expressed, developmentally down-regulated 9" Q14511 6 11183298-11382348 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Cell cycle, Cell division, Growth regulation, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Neutrophils: 3925.4" "Group enriched" "Detected in all" 5 "endothelial cell: 386.7;leukocyte: 471.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009689, CAB009720, HPA038768, HPA039270, HPA072955" Uncertain Supported Nucleoplasm,Cytosol NA Yes "Cluster 28: Neutrophils - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 33 "Nucleoplasm, Cytosol" "CAB009720: , HPA009689: , HPA038768: , HPA039270: , HPA072955: " "potential prognostic favorable (5.10e-4)" "unprognostic (2.12e-2)" "unprognostic (2.34e-1)" "unprognostic (1.36e-1)" "unprognostic (3.73e-3)" "unprognostic (1.52e-1)" "unprognostic (9.36e-2)" "unprognostic (1.64e-3)" "unprognostic (4.96e-2)" "unprognostic (2.52e-1)" "validated prognostic favorable (5.52e-8)" "validated prognostic favorable (7.24e-5)" "unprognostic (1.49e-2)" "unprognostic (5.49e-2)" "unprognostic (5.37e-2)" "unprognostic (1.14e-2)" "unprognostic (2.05e-2)" "unprognostic (2.28e-1)" "unprognostic (5.89e-2)" "unprognostic (7.94e-2)" "unprognostic (9.75e-2)" "unprognostic (7.49e-2)" "unprognostic (2.60e-1)" "unprognostic (2.72e-1)" "unprognostic (1.25e-2)" "unprognostic (1.64e-1)" "unprognostic (1.14e-1)" "unprognostic (9.64e-3)" "unprognostic (1.45e-1)" "unprognostic (2.15e-1)" "unprognostic (2.25e-1)" NEFH "NF-H, NFH" ENSG00000100285 "Neurofilament heavy chain" P12036 22 29480218-29491390 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Amyotrophic lateral sclerosis, Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 83.8;prostate: 230.9" "Cell type enriched" "Detected in many" 34 "Prostatic glandular cells: 1739.1" "Cell type enhanced" "Detected in all" "lower rhombic lip: 112.6;mammillary body: 92.3" "Group enriched" "Detected in many" 6 "Prostate Adenocarcinoma (TCGA): 208.5;Testicular Germ Cell Tumor (TCGA): 75.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 4.7" "Lineage enriched" "Detected in single" 5 "monocytes: 4.7" "Cancer enhanced" "Detected in many" "cervical cancer: 55.1;Neuroblastoma: 43.5" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Adrenal cortex cells, Colon - Colon enteroendocrine cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Prostate glandular cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "spinal cord: 1717.6" "CAB007786, HPA061615" Enhanced Approved "Nucleoplasm,Nuclear bodies,Primary cilium,Primary cilium transition zone,Centrosome,Basal body,Cytosol" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 65: Brain - Transcription" "Cluster 45: Non-specific - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 4 "Nuclear bodies, Centrosome, Basal body" "Nucleoplasm, Primary cilium, Primary cilium transition zone, Cytosol" "CAB007786: , HPA061615: " "potential prognostic favorable (8.54e-6)" "unprognostic (8.71e-2)" "unprognostic (5.29e-2)" "unprognostic (1.92e-1)" "unprognostic (1.28e-1)" "unprognostic (6.39e-2)" "unprognostic (1.26e-1)" "unprognostic (2.02e-1)" "unprognostic (9.37e-2)" "unprognostic (2.00e-2)" "unprognostic (3.60e-1)" "unprognostic (8.72e-2)" "unprognostic (8.83e-2)" "unprognostic (8.24e-2)" "unprognostic (2.10e-2)" "unprognostic (3.50e-1)" "unprognostic (4.08e-2)" "unprognostic (2.14e-1)" "unprognostic (1.51e-1)" NEFL "CMT1F, CMT2E, NF68, NFL, PPP1R110" ENSG00000277586 "Neurofilament light chain" P07196 8 24950955-24956721 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "brain: 298.8;retina: 82.9" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 24.5;Brain excitatory neurons: 76.1;Brain inhibitory neurons: 52.9;Corticotrophs: 98.6;Esophageal suprabasal cells: 26.1;Gonadotrophs: 32.0;Oocytes: 50.7;Other brain neurons: 114.2;Retinal ganglion cells: 92.7;Suprabasal keratinocytes: 23.0" "Cell type enhanced" "Detected in all" "lower rhombic lip: 444.3;thalamic excitatory: 281.4" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 84.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "memory CD4 T-cell: 11.2" "Lineage enriched" "Detected in single" 113 "T-cells: 11.2" "Cancer enhanced" "Detected in many" "Rhabdoid: 73.2" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014850, HPA015021" Enhanced Supported Approved "Nucleoplasm,Intermediate filaments,Midbody" Yes NA 720000 "Cluster 39: T-cells - T-cell receptor" "Cluster 73: Brain - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 1: Neuronal - Visual perception" "Cluster 98: Neurons - Neurotransmission & signaling" 93 "Nucleoplasm, Intermediate filaments" Midbody "HPA014850: , HPA015021: " "unprognostic (4.49e-2)" "unprognostic (2.78e-2)" "unprognostic (1.63e-1)" "unprognostic (6.17e-2)" "unprognostic (5.79e-2)" "unprognostic (3.04e-2)" "unprognostic (5.92e-2)" "unprognostic (1.78e-1)" "unprognostic (3.72e-1)" "unprognostic (2.31e-3)" "unprognostic (1.57e-3)" "unprognostic (6.50e-2)" "unprognostic (1.23e-1)" "unprognostic (6.24e-2)" "unprognostic (2.51e-1)" "unprognostic (4.38e-2)" "unprognostic (1.88e-1)" "unprognostic (4.39e-1)" NEFM "NEF3, NF-M, NFM" ENSG00000104722 "Neurofilament medium chain" P07197 8 24913758-24919098 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "brain: 308.0;retina: 84.1" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 49.8;Breast myoepithelial cells: 42.2;Corticotrophs: 114.9;Early spermatids: 81.4;Gonadotrophs: 151.8;Late primary spermatocytes: 121.9;Late spermatids: 178.3;Oocytes: 50.7;Other brain neurons: 54.5;Pancreatic islet cells: 58.5;Retinal ganglion cells: 135.2;Thymic myoid cells: 58.5" "Cell type enhanced" "Detected in all" "lower rhombic lip: 249.4;thalamic excitatory: 202.2" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 16.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 56.7;Neuroblastoma: 79.7;Rhabdoid: 129.8" "Colon - Colon enteroendocrine cells, Pituitary gland - Gonadotropes, Testis - Early spermatids, Testis - Late spermatids" "CAB010900, CAB012976, HPA022845, HPA023138" Enhanced Enhanced "Intermediate filaments" Yes NA 800000 "Cluster 73: Brain - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 98: Neurons - Neurotransmission & signaling" 43 "Intermediate filaments" "CAB010900: , CAB012976: , HPA022845: , HPA023138: " "unprognostic (1.15e-1)" "unprognostic (4.20e-1)" "unprognostic (1.20e-1)" "unprognostic (1.90e-1)" "unprognostic (1.84e-1)" "unprognostic (1.67e-2)" "unprognostic (1.17e-1)" "unprognostic (2.09e-1)" "unprognostic (6.99e-2)" "unprognostic (3.29e-2)" "unprognostic (2.23e-1)" "unprognostic (1.11e-2)" "unprognostic (1.33e-1)" "unprognostic (1.12e-1)" NEGR1 "IGLON4, KILON, MGC46680, Ntra" ENSG00000172260 "Neuronal growth regulator 1" Q7Z3B1 1 71395943-72282539 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 31.2" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 1921.0;Brain inhibitory neurons: 1564.4;Cone photoreceptor cells: 1409.7;Corticotrophs: 1720.7;Fibro-adipogenic progenitors: 4285.0;Fibroblasts: 1059.9;Lactotrophs: 1631.0;Leydig cells: 2587.9;Other brain neurons: 1312.9;Retinal amacrine cells: 1246.0;Rod photoreceptor cells: 2355.1;Schwann cells: 1373.2;Somatotrophs: 1267.5;Thymocytes: 1311.1;Thyrotrophs: 2372.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Prostate - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011894 Uncertain Approved "Vesicles,Actin filaments,Cytosol" NA NA 14000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 2 "Vesicles, Actin filaments, Cytosol" "HPA011894: " "unprognostic (8.82e-3)" "unprognostic (1.96e-1)" "unprognostic (6.68e-3)" "unprognostic (2.92e-1)" "unprognostic (1.01e-2)" "unprognostic (1.53e-1)" "unprognostic (1.18e-3)" "potential prognostic favorable (9.40e-4)" "unprognostic (1.72e-2)" "unprognostic (3.33e-2)" "unprognostic (2.63e-1)" "unprognostic (4.62e-1)" "unprognostic (7.46e-2)" "unprognostic (4.73e-2)" "unprognostic (1.32e-1)" "unprognostic (6.64e-2)" "unprognostic (1.24e-2)" "unprognostic (2.03e-2)" "unprognostic (7.23e-3)" "unprognostic (7.37e-2)" "unprognostic (8.68e-2)" NEIL1 "FLJ22402, FPG1, hFPG1, NEI1" ENSG00000140398 "Nei like DNA glycosylase 1" Q96FI4 15 75346955-75357115 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Glycosidase, Hydrolase, Lyase, Multifunctional enzyme" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 72.2;Cardiomyocytes: 119.0;Epicardial cells: 150.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 5.3;memory B-cell: 4.9;naive B-cell: 6.7;NK-cell: 16.3" "Group enriched" "Detected in many" 11 "B-cells: 6.7;NK-cells: 16.3;T-cells: 5.3" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054084 Approved Supported Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 178 Nucleoplasm "HPA054084: " "unprognostic (9.69e-3)" "unprognostic (4.30e-2)" "unprognostic (8.28e-3)" "unprognostic (7.85e-3)" "unprognostic (7.58e-3)" "unprognostic (2.18e-1)" "unprognostic (2.31e-1)" "unprognostic (2.36e-1)" "unprognostic (6.34e-2)" "unprognostic (2.49e-3)" "unprognostic (3.54e-3)" "potential prognostic favorable (2.41e-4)" "potential prognostic favorable (7.59e-6)" "unprognostic (3.61e-2)" "unprognostic (8.16e-2)" "potential prognostic favorable (1.48e-4)" "unprognostic (4.31e-2)" "unprognostic (6.62e-2)" "unprognostic (3.13e-2)" "unprognostic (1.47e-1)" "unprognostic (3.25e-1)" "potential prognostic favorable (4.05e-4)" "unprognostic (4.00e-1)" "unprognostic (3.98e-2)" "unprognostic (7.91e-2)" "unprognostic (2.78e-1)" "unprognostic (1.98e-1)" "unprognostic (4.58e-2)" "unprognostic (4.43e-2)" "unprognostic (1.57e-1)" "unprognostic (5.62e-2)" NEIL2 "FLJ31644, MGC2832, MGC4505, NEH2" ENSG00000154328 "Nei like DNA glycosylase 2" Q969S2 8 11769639-11787345 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Glycosidase, Hydrolase, Lyase, Multifunctional enzyme" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 7.0;Brain excitatory neurons: 10.8;Brain inhibitory neurons: 10.7;Choroid plexus epithelial cells: 7.9;Ependymal cells: 7.4;Microglia: 7.8;Oligodendrocyte progenitor cells: 9.0;Oligodendrocytes: 6.6;Other brain neurons: 17.7;Papillary tip epithelial cells: 5.7;Proximal tubule cells: 6.7;Renal collecting duct principal cells: 7.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen), Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA073029, HPA073916" Supported Nucleoplasm,Vesicles NA NA "Cluster 24: Non-specific - Transcription" "Cluster 36: Brain & Liver - Signaling" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 40: Non-specific - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" 9 Nucleoplasm Vesicles "HPA073029: , HPA073916: " "unprognostic (3.90e-3)" "unprognostic (1.07e-1)" "potential prognostic favorable (4.90e-4)" "unprognostic (5.17e-2)" "unprognostic (9.56e-2)" "unprognostic (1.48e-1)" "unprognostic (2.14e-2)" "unprognostic (5.05e-2)" "unprognostic (1.44e-1)" "unprognostic (1.18e-3)" "unprognostic (6.28e-3)" "unprognostic (3.12e-2)" "unprognostic (5.41e-2)" "unprognostic (1.89e-1)" "unprognostic (1.07e-2)" "unprognostic (1.34e-1)" "unprognostic (3.78e-2)" "unprognostic (6.73e-2)" "unprognostic (2.70e-1)" "unprognostic (3.07e-1)" "unprognostic (7.60e-2)" "unprognostic (4.59e-3)" "unprognostic (7.67e-2)" "unprognostic (4.61e-2)" "unprognostic (5.77e-2)" "unprognostic (3.94e-2)" "unprognostic (4.22e-2)" "unprognostic (1.45e-1)" "unprognostic (9.45e-2)" "unprognostic (2.84e-1)" "potential prognostic favorable (4.63e-4)" NEIL3 "FLJ10858, FPG2, hFPG2, hNEI3, ZGRF3" ENSG00000109674 "Nei like DNA glycosylase 3" Q8TAT5 4 177309874-177362936 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Glycosidase, Hydrolase, Lyase, Multifunctional enzyme" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 6.3;lymphoid tissue: 22.0" "Cell type enhanced" "Detected in some" "Erythrocyte progenitors: 34.0;Megakaryocyte progenitors: 18.1;Megakaryocytes: 12.4;Monocyte progenitors: 67.9;Neutrophil progenitors: 74.5;Neutrophils: 21.9;Oocytes: 18.4" "Cell type enhanced" "Detected in single" "leukocyte: 1.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Mitotic cells (Thyroid)" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebellum: 4.4" HPA065761 Enhanced Nucleoplasm NA Yes "Cluster 9: T-regs - Cell cycle regulation" "Cluster 80: Thymus - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 27: Non-specific - Cell proliferation" 12 Nucleoplasm "HPA065761: " "unprognostic (1.32e-3)" "unprognostic (1.57e-1)" "unprognostic (4.10e-2)" "unprognostic (1.22e-1)" "unprognostic (9.22e-2)" "unprognostic (2.73e-2)" "unprognostic (3.42e-2)" "unprognostic (3.96e-2)" "unprognostic (1.55e-1)" "validated prognostic unfavorable (6.86e-8)" "validated prognostic unfavorable (2.36e-4)" "potential prognostic unfavorable (2.20e-6)" "unprognostic (5.82e-3)" "unprognostic (3.23e-1)" "unprognostic (2.93e-1)" "unprognostic (1.58e-1)" "unprognostic (1.80e-1)" "unprognostic (1.40e-3)" "unprognostic (1.64e-2)" "unprognostic (2.23e-2)" "unprognostic (1.45e-2)" "unprognostic (1.30e-2)" "unprognostic (2.00e-1)" "unprognostic (1.21e-1)" NEK1 "KIAA1901, NY-REN-55" ENSG00000137601 "NIMA related kinase 1" Q96PY6 4 169369704-169612632 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Cilium biogenesis/degradation, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Amyotrophic lateral sclerosis, Ciliopathy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial ciliated cells: 458.3;Somatotrophs: 447.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Endothelial cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020873, HPA040413" Approved Supported "Nucleoplasm,Primary cilium,Centriolar satellite,Cytosol" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 61: Non-specific - Transcription" "Cluster 44: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 103: Non-specific - Basic cellular processes" 35 Nucleoplasm "Primary cilium, Centriolar satellite, Cytosol" "HPA020873: , HPA040413: " "unprognostic (1.85e-1)" "unprognostic (1.94e-1)" "unprognostic (4.03e-2)" "unprognostic (1.11e-1)" "unprognostic (2.81e-1)" "unprognostic (3.74e-1)" "unprognostic (9.29e-2)" "unprognostic (1.11e-1)" "unprognostic (3.21e-1)" "unprognostic (1.05e-3)" "validated prognostic favorable (8.57e-7)" "validated prognostic favorable (2.73e-4)" "unprognostic (1.25e-1)" "unprognostic (4.65e-2)" "unprognostic (3.14e-2)" "unprognostic (1.30e-1)" "unprognostic (3.26e-1)" "unprognostic (1.12e-1)" "unprognostic (1.06e-1)" "unprognostic (2.55e-2)" "unprognostic (2.10e-1)" "unprognostic (1.07e-2)" "unprognostic (9.85e-2)" "unprognostic (1.30e-1)" "unprognostic (3.26e-2)" "unprognostic (8.35e-2)" "unprognostic (6.93e-2)" "unprognostic (2.20e-1)" "unprognostic (2.02e-2)" "unprognostic (8.65e-2)" NEK10 FLJ32685 ENSG00000163491 "NIMA related kinase 10" Q6ZWH5 3 27106484-27369460 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Ciliopathy, Disease variant, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 33.0;tongue: 13.7" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 273.3;Cone photoreceptor cells: 443.0;Endometrial ciliated cells: 559.3;Ependymal cells: 820.2;Fallopian tube ciliated cells: 534.5;Loop of henle epithelial cells: 305.2;Myonuclei: 552.9;Respiratory ciliated cells: 1481.7" "Cell type enhanced" "Detected in all" "ependymal cell: 882.0" "Group enriched" "Detected in many" 5 "Breast Invasive Carcinoma (TCGA): 10.9;Uterine Corpus Endometrial Carcinoma (TCGA): 2.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Adrenocortical cancer: 7.0" "Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA038941 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 29: Forebrain - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" "Nucleoplasm, Vesicles" "HPA038941: " "unprognostic (5.18e-3)" "unprognostic (1.94e-3)" "unprognostic (7.83e-2)" "unprognostic (3.38e-1)" "unprognostic (7.39e-2)" "unprognostic (6.96e-2)" "unprognostic (2.02e-2)" "unprognostic (1.20e-1)" "unprognostic (4.80e-2)" "unprognostic (2.10e-1)" "unprognostic (2.17e-1)" "unprognostic (3.11e-2)" "unprognostic (4.21e-2)" "unprognostic (1.15e-1)" "unprognostic (3.15e-2)" "unprognostic (1.93e-1)" "unprognostic (2.84e-2)" NEK11 FLJ23495 ENSG00000114670 "NIMA related kinase 11" Q8NG66 3 131026850-131350465 "Enzymes, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 41.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 375.7;Choroid plexus epithelial cells: 796.6;Early spermatids: 302.0;Endometrial ciliated cells: 361.0;Ependymal cells: 1378.7;Epididymal efferent duct ciliated cells: 332.4;Fallopian tube ciliated cells: 408.7;Late spermatids: 307.0;Respiratory ciliated cells: 779.5" "Group enriched" "Detected in all" 4 "choroid plexus epithelial cell: 699.1;ependymal cell: 1507.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA016908 Approved Supported Nucleoplasm NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" 3 Nucleoplasm "HPA016908: " "unprognostic (2.32e-2)" "unprognostic (1.69e-1)" "unprognostic (2.81e-1)" "unprognostic (3.19e-2)" "unprognostic (2.03e-1)" "unprognostic (4.78e-2)" "unprognostic (3.51e-2)" "unprognostic (9.35e-3)" "unprognostic (2.66e-2)" "potential prognostic favorable (1.76e-6)" "unprognostic (1.36e-2)" "potential prognostic favorable (7.56e-5)" "unprognostic (8.52e-2)" "unprognostic (1.46e-1)" "unprognostic (1.32e-1)" "unprognostic (1.63e-2)" "unprognostic (5.44e-3)" "unprognostic (4.33e-1)" "unprognostic (1.54e-1)" "unprognostic (1.89e-1)" "unprognostic (5.25e-2)" "unprognostic (8.46e-2)" "unprognostic (4.47e-2)" "unprognostic (4.51e-2)" "unprognostic (1.31e-1)" "unprognostic (4.96e-2)" "unprognostic (1.27e-1)" "unprognostic (1.11e-2)" "unprognostic (1.96e-2)" NEK2 "NEK2A, NLK1, PPP1R111, RP67" ENSG00000117650 "NIMA related kinase 2" P51955 1 211658657-211675630 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Meiosis, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 16.7;lymphoid tissue: 17.9;testis: 62.8" "Cell type enriched" "Detected in many" 4 "Late primary spermatocytes: 413.5" "Cell type enhanced" "Detected in some" "ependymal cell: 2.5;hippocampal CA4: 2.6;upper-layer intratelencephalic: 1.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Thyroid gland - Mitotic cells (Thyroid)" "Region enhanced" "Detected in many" "cerebellum: 5.7" "Low region specificity" "Detected in all" "CAB017530, HPA064967" Enhanced Supported "Nucleoplasm,Cytokinetic bridge,Primary cilium,Centrosome,Basal body" Yes Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 39: Testis - Nuclear processes" "Cluster 48: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 48 "Nucleoplasm, Centrosome" "Cytokinetic bridge, Primary cilium, Basal body" "CAB017530: , HPA064967: " "unprognostic (3.15e-3)" "unprognostic (3.28e-2)" "unprognostic (1.42e-1)" "unprognostic (1.64e-1)" "unprognostic (6.47e-2)" "unprognostic (6.65e-2)" "unprognostic (1.11e-1)" "unprognostic (6.35e-2)" "unprognostic (8.54e-2)" "potential prognostic unfavorable (1.83e-4)" "validated prognostic unfavorable (1.77e-7)" "validated prognostic unfavorable (6.90e-6)" "potential prognostic unfavorable (1.70e-8)" "validated prognostic unfavorable (1.06e-6)" "validated prognostic unfavorable (1.06e-6)" "potential prognostic unfavorable (6.66e-5)" "unprognostic (1.98e-3)" "unprognostic (3.77e-2)" "unprognostic (2.41e-1)" "unprognostic (1.87e-1)" "unprognostic (3.81e-1)" "potential prognostic unfavorable (2.35e-4)" "unprognostic (6.18e-3)" "unprognostic (6.85e-2)" "unprognostic (2.73e-2)" "unprognostic (2.15e-2)" "unprognostic (1.03e-2)" "unprognostic (1.16e-1)" "unprognostic (1.31e-1)" "unprognostic (8.97e-2)" NEK3 "HSPK36, MGC29949" ENSG00000136098 "NIMA related kinase 3" P51956 13 52132639-52159861 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 121.7" "Cell type enhanced" "Detected in all" "endothelial cell: 123.8;oligodendrocyte: 159.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019062, HPA043230" Enhanced Approved "Plasma membrane,Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium" Yes NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 67: Testis - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 19: Non-specific - Unknown function" "Cluster 104: Brain endothelial cells - Blood brain barrier" 1 Microtubules "Plasma membrane, Cytokinetic bridge, Mitotic spindle, Primary cilium" "HPA019062: , HPA043230: " "unprognostic (6.93e-2)" "unprognostic (5.91e-2)" "unprognostic (2.50e-1)" "unprognostic (8.82e-2)" "unprognostic (9.24e-2)" "unprognostic (1.01e-1)" "unprognostic (1.18e-2)" "unprognostic (6.75e-3)" "unprognostic (1.25e-1)" "unprognostic (7.93e-2)" "unprognostic (4.94e-2)" "unprognostic (8.88e-2)" "unprognostic (5.54e-2)" "unprognostic (2.15e-1)" "unprognostic (3.92e-2)" "unprognostic (6.94e-2)" "unprognostic (8.35e-2)" "unprognostic (1.55e-2)" "unprognostic (1.72e-1)" "unprognostic (3.56e-2)" "unprognostic (4.08e-2)" "unprognostic (5.68e-2)" "unprognostic (3.58e-2)" "unprognostic (5.85e-3)" "unprognostic (2.35e-2)" "unprognostic (4.75e-2)" "unprognostic (2.27e-1)" "unprognostic (8.18e-3)" "unprognostic (1.34e-2)" "unprognostic (4.34e-2)" "unprognostic (5.86e-3)" NEK4 "NRK2, pp12301, STK2" ENSG00000114904 "NIMA related kinase 4" P51957 3 52708444-52770946 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 43.0" "Cell type enhanced" "Detected in many" "Ependymal cells: 102.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015750, HPA058543" Enhanced Supported Cytosol NA NA "Cluster 41: Basophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 30 Cytosol "HPA015750: , HPA058543: " "unprognostic (2.25e-2)" "unprognostic (9.96e-2)" "unprognostic (2.24e-1)" "unprognostic (1.14e-2)" "unprognostic (3.52e-3)" "unprognostic (2.20e-2)" "unprognostic (3.56e-1)" "unprognostic (2.54e-1)" "unprognostic (2.05e-1)" "unprognostic (2.71e-2)" "potential prognostic favorable (5.18e-6)" "unprognostic (2.39e-3)" "unprognostic (7.59e-2)" "unprognostic (3.86e-2)" "unprognostic (4.11e-1)" "unprognostic (1.12e-1)" "unprognostic (6.20e-3)" "unprognostic (5.67e-2)" "unprognostic (1.78e-1)" "unprognostic (2.49e-1)" "unprognostic (5.43e-2)" "unprognostic (4.13e-2)" "unprognostic (3.45e-1)" "unprognostic (1.08e-1)" "unprognostic (1.04e-2)" "unprognostic (3.41e-1)" "unprognostic (4.82e-2)" "unprognostic (2.00e-1)" "unprognostic (2.55e-1)" "unprognostic (1.02e-1)" "unprognostic (2.48e-1)" NEK5 ENSG00000197168 "NIMA related kinase 5" Q6P3R8 13 52033611-52129092 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 8.1;testis: 10.0" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 152.4;Endometrial ciliated cells: 188.0;Ependymal cells: 663.9;Epididymal efferent duct ciliated cells: 164.5;Fallopian tube ciliated cells: 270.0;Respiratory ciliated cells: 469.4" "Cell type enriched" "Detected in all" 5 "ependymal cell: 738.2" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 6.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA035565, HPA037016, HPA041399" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 27: Breast cancer - Unknown function" "Cluster 34: Ciliated cells - Cilia assembly & function" 2 Nucleoplasm Cytosol "HPA035565: , HPA037016: , HPA041399: " "unprognostic (1.37e-1)" "unprognostic (1.09e-1)" "unprognostic (6.54e-3)" "unprognostic (1.49e-1)" "unprognostic (1.42e-2)" "unprognostic (4.00e-2)" "unprognostic (1.51e-1)" "unprognostic (2.01e-2)" "unprognostic (1.05e-1)" "unprognostic (7.09e-3)" "unprognostic (5.44e-2)" "unprognostic (2.21e-1)" "unprognostic (1.27e-1)" "unprognostic (7.12e-3)" "unprognostic (9.55e-2)" "unprognostic (1.43e-1)" "unprognostic (6.04e-2)" NEK6 SID6-1512 ENSG00000119408 "NIMA related kinase 6" Q9HC98 9 124257606-124353307 "Enzymes, Predicted intracellular proteins, Transporters" "Apoptosis, Cell cycle, Cell division, Chromosome partition, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 64.3" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 173.3;Hofbauer cells: 159.8;Late spermatids: 153.3;Migrating cytotrophoblasts: 156.8" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 87.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB045993, HPA056828" Approved Supported "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 36: Brain & Liver - Signaling" "Cluster 39: Astrocytes - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 48 "Nucleoplasm, Cytosol" "Centriolar satellite" "CAB045993: , HPA056828: " "unprognostic (8.99e-2)" "unprognostic (5.62e-2)" "unprognostic (3.91e-1)" "potential prognostic unfavorable (1.09e-4)" "unprognostic (1.76e-1)" "unprognostic (7.19e-2)" "unprognostic (1.57e-1)" "unprognostic (1.85e-2)" "unprognostic (1.64e-2)" "unprognostic (2.03e-1)" "potential prognostic favorable (9.25e-5)" "unprognostic (8.08e-3)" "unprognostic (6.71e-3)" "potential prognostic unfavorable (7.28e-4)" "unprognostic (5.21e-2)" "unprognostic (1.57e-2)" "potential prognostic unfavorable (7.27e-4)" "potential prognostic unfavorable (4.32e-4)" "unprognostic (9.93e-2)" "unprognostic (1.34e-2)" "unprognostic (1.31e-2)" "unprognostic (1.25e-2)" "unprognostic (1.57e-1)" "unprognostic (1.76e-2)" "unprognostic (1.37e-1)" "unprognostic (2.10e-1)" "unprognostic (1.78e-1)" "unprognostic (2.39e-1)" "unprognostic (1.48e-2)" "unprognostic (3.13e-2)" "unprognostic (8.06e-3)" NEK7 ENSG00000151414 "NIMA related kinase 7" Q8TDX7 1 198156994-198322420 "Enzymes, Predicted intracellular proteins, Transporters" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 131.4" "Cell type enhanced" "Detected in all" "Adrenal cortex cells: 612.2;Neutrophils: 794.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015520, HPA018193" Approved Supported Nucleoplasm Yes No "Cluster 1: T-cells - Unknown function" "Cluster 35: Non-specific - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 24: Neutrophils - Innate immunity signal integration" 97 Nucleoplasm "HPA015520: , HPA018193: " "unprognostic (6.34e-3)" "unprognostic (1.65e-1)" "unprognostic (6.22e-2)" "unprognostic (2.20e-2)" "unprognostic (1.04e-1)" "unprognostic (3.91e-2)" "unprognostic (1.21e-1)" "unprognostic (3.20e-1)" "unprognostic (3.26e-2)" "unprognostic (1.19e-1)" "potential prognostic favorable (6.12e-7)" "unprognostic (1.89e-2)" "unprognostic (3.30e-2)" "unprognostic (1.67e-2)" "unprognostic (5.33e-1)" "unprognostic (3.47e-1)" "unprognostic (1.65e-1)" "unprognostic (1.94e-1)" "unprognostic (8.05e-2)" "unprognostic (4.71e-2)" "potential prognostic unfavorable (6.72e-4)" "potential prognostic unfavorable (8.50e-4)" "unprognostic (7.02e-2)" "unprognostic (1.33e-1)" "unprognostic (1.40e-1)" "unprognostic (1.64e-1)" "unprognostic (8.06e-2)" "unprognostic (5.57e-3)" "unprognostic (1.84e-1)" "unprognostic (2.60e-3)" "unprognostic (9.61e-2)" NEK8 NPHP9 ENSG00000160602 "NIMA related kinase 8" Q86SG6 17 28725897-28743455 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Ciliopathy, Disease variant, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Epididymal basal cells: 49.7;pDCs: 120.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 14.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040661, HPA040679" Approved Approved "Nuclear speckles,Microtubules,Mitotic spindle,Primary cilium" Yes NA "Cluster 41: Basophils - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 23 Microtubules "Nuclear speckles, Mitotic spindle, Primary cilium" "HPA040661: , HPA040679: " "unprognostic (3.92e-2)" "unprognostic (9.29e-2)" "unprognostic (7.04e-2)" "unprognostic (1.88e-1)" "potential prognostic unfavorable (5.56e-4)" "unprognostic (2.02e-2)" "unprognostic (7.64e-2)" "potential prognostic unfavorable (8.77e-4)" "unprognostic (2.13e-2)" "unprognostic (7.72e-2)" "unprognostic (2.02e-1)" "unprognostic (7.29e-3)" "potential prognostic favorable (8.91e-4)" "unprognostic (1.11e-2)" "unprognostic (2.88e-2)" "unprognostic (2.37e-2)" "unprognostic (1.14e-1)" "unprognostic (3.38e-1)" "unprognostic (2.89e-2)" "unprognostic (1.65e-1)" "unprognostic (1.79e-1)" "unprognostic (1.66e-3)" "unprognostic (4.44e-2)" "unprognostic (2.23e-1)" "unprognostic (4.22e-2)" "unprognostic (6.55e-2)" "unprognostic (1.23e-1)" "unprognostic (3.09e-1)" "unprognostic (2.62e-1)" "unprognostic (5.24e-2)" "unprognostic (3.38e-2)" NEK9 "DKFZp434D0935, MGC16714, Nek8, NERCC, NERCC1" ENSG00000119638 "NIMA related kinase 9" Q8TD19 14 75079353-75127344 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 184.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001405 Approved NA NA 4200 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 54 "HPA001405: " "unprognostic (3.41e-3)" "unprognostic (1.79e-1)" "unprognostic (1.71e-1)" "unprognostic (8.16e-2)" "unprognostic (2.73e-1)" "unprognostic (3.30e-2)" "unprognostic (3.97e-1)" "unprognostic (1.32e-1)" "unprognostic (3.57e-1)" "unprognostic (2.13e-1)" "potential prognostic favorable (9.65e-8)" "unprognostic (2.70e-3)" "unprognostic (1.97e-1)" "unprognostic (1.13e-1)" "unprognostic (3.35e-1)" "unprognostic (1.31e-1)" "unprognostic (1.11e-1)" "unprognostic (1.44e-1)" "unprognostic (4.36e-2)" "unprognostic (6.27e-3)" "unprognostic (4.17e-1)" "unprognostic (4.83e-2)" "unprognostic (8.16e-2)" "unprognostic (1.70e-1)" "unprognostic (7.08e-2)" "unprognostic (2.62e-1)" "unprognostic (8.56e-2)" "unprognostic (7.61e-2)" "unprognostic (4.65e-1)" "unprognostic (1.15e-3)" "unprognostic (1.31e-1)" NELFA "NELF-A, WHSC2" ENSG00000185049 "Negative elongation factor complex member A" Q9H3P2 4 1982717-2041903 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ependymal cells: 222.7;Sertoli cells: 204.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009960, HPA039858, HPA043931" Supported Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 24: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 34: Ciliated cells - Cilia assembly & function" 45 Nucleoplasm "Nuclear bodies" "CAB009960: , HPA039858: , HPA043931: " "unprognostic (2.98e-1)" "unprognostic (1.71e-1)" "unprognostic (1.56e-2)" "unprognostic (1.30e-1)" "unprognostic (8.53e-2)" "unprognostic (2.39e-1)" "unprognostic (6.68e-3)" "unprognostic (5.94e-2)" "unprognostic (2.23e-1)" "unprognostic (5.26e-3)" "unprognostic (1.35e-2)" "unprognostic (1.85e-1)" "unprognostic (1.25e-2)" "unprognostic (2.87e-2)" "unprognostic (7.82e-3)" "unprognostic (9.36e-2)" "unprognostic (2.74e-2)" "unprognostic (4.64e-1)" "unprognostic (9.88e-3)" "unprognostic (1.40e-1)" "unprognostic (1.48e-2)" "unprognostic (1.82e-3)" "unprognostic (1.02e-1)" "unprognostic (8.65e-2)" "unprognostic (1.80e-1)" "unprognostic (3.56e-2)" "unprognostic (3.17e-1)" "unprognostic (1.33e-1)" "unprognostic (2.06e-1)" NELFB "COBRA1, KIAA1182, NELF-B" ENSG00000188986 "Negative elongation factor complex member B" Q8WX92 9 137255327-137273542 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020259 Supported Supported Nucleoplasm NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 20: Non-specific - Transcription regulation" 46 Nucleoplasm "HPA020259: " "unprognostic (7.21e-3)" "unprognostic (7.07e-2)" "unprognostic (2.96e-2)" "unprognostic (1.30e-1)" "unprognostic (8.31e-2)" "unprognostic (3.34e-1)" "unprognostic (4.67e-2)" "unprognostic (7.96e-2)" "unprognostic (2.01e-1)" "potential prognostic favorable (2.43e-5)" "unprognostic (8.70e-3)" "unprognostic (8.06e-2)" "unprognostic (1.15e-3)" "unprognostic (2.14e-1)" "unprognostic (6.58e-2)" "unprognostic (7.98e-3)" "unprognostic (1.41e-2)" "unprognostic (2.22e-1)" "unprognostic (1.88e-1)" "unprognostic (1.84e-2)" "unprognostic (2.59e-1)" "unprognostic (1.29e-2)" "unprognostic (6.08e-2)" "unprognostic (1.23e-2)" "unprognostic (1.02e-1)" "unprognostic (4.70e-2)" "unprognostic (8.80e-2)" "unprognostic (2.64e-1)" "unprognostic (2.85e-3)" NELFCD "HSPC130, NELF-C, NELF-D, TH1, TH1L" ENSG00000101158 "Negative elongation factor complex member C/D" Q8IXH7 20 58981208-58995133 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 167.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050641, HPA066262, HPA074936" Enhanced Supported "Nucleoplasm,Nuclear bodies,Vesicles,Cytosol" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 22 "Nucleoplasm, Nuclear bodies" "Vesicles, Cytosol" "HPA050641: , HPA066262: , HPA074936: " "unprognostic (1.03e-2)" "unprognostic (2.50e-3)" "unprognostic (1.80e-1)" "unprognostic (1.98e-1)" "unprognostic (1.87e-1)" "unprognostic (2.29e-1)" "unprognostic (9.87e-2)" "unprognostic (2.34e-1)" "unprognostic (1.73e-3)" "potential prognostic favorable (1.12e-7)" "unprognostic (7.71e-2)" "unprognostic (1.25e-1)" "potential prognostic unfavorable (1.42e-4)" "unprognostic (4.74e-2)" "unprognostic (1.13e-2)" "unprognostic (3.48e-2)" "unprognostic (7.06e-2)" "unprognostic (2.02e-1)" "unprognostic (5.81e-2)" "unprognostic (2.96e-1)" "potential prognostic unfavorable (2.06e-4)" "unprognostic (8.00e-3)" "unprognostic (3.89e-2)" "unprognostic (1.93e-2)" "unprognostic (4.45e-1)" "unprognostic (3.16e-1)" "unprognostic (3.79e-1)" "unprognostic (7.61e-2)" "unprognostic (1.06e-1)" NELFE "D6S45, NELF-E, RD, RDBP, RDP" ENSG00000204356 "Negative elongation factor complex member E" P18615 6 31952087-31959038 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Late spermatids: 2521.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007187, HPA007594, HPA046502" Enhanced Enhanced "Nucleoplasm,Nuclear bodies" No No "Cluster 10: Non-specific - Membrane trafficking" "Cluster 67: Testis - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 28: Non-specific - Nuclear processes" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 32 "Nucleoplasm, Nuclear bodies" "HPA007187: , HPA007594: , HPA046502: " "potential prognostic unfavorable (6.09e-4)" "unprognostic (7.12e-2)" "unprognostic (2.21e-1)" "unprognostic (1.94e-1)" "unprognostic (1.93e-2)" "unprognostic (1.80e-1)" "unprognostic (2.54e-3)" "unprognostic (1.10e-1)" "unprognostic (2.73e-2)" "unprognostic (1.15e-1)" "unprognostic (4.51e-2)" "unprognostic (2.20e-1)" "unprognostic (1.21e-2)" "unprognostic (9.13e-3)" "unprognostic (1.54e-2)" "unprognostic (1.72e-1)" "unprognostic (2.16e-2)" "unprognostic (4.34e-2)" "unprognostic (2.24e-1)" "unprognostic (5.86e-2)" "unprognostic (6.16e-2)" "unprognostic (6.55e-3)" "unprognostic (4.51e-2)" "unprognostic (1.86e-1)" "unprognostic (1.26e-1)" "unprognostic (5.19e-2)" "unprognostic (1.76e-1)" "unprognostic (3.41e-2)" "unprognostic (8.09e-2)" NELL1 "FLJ45906, IDH3GL" ENSG00000165973 "Neural EGFL like 1" Q92832 11 20669551-21575686 "Predicted secreted proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 12.8;kidney: 15.5" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 276.9;Brain inhibitory neurons: 361.2;Distal convoluted tubule cells: 369.3;Gonadotrophs: 378.6;Late primary spermatocytes: 161.8;Loop of henle epithelial cells: 241.5;Medullary thymic epithelial cells: 314.4;Mesothelial cells: 145.6;Oligodendrocyte progenitor cells: 388.7;Other brain neurons: 116.1;Podocytes: 257.6;Renal collecting duct intercalated cells: 123.2;Renal connecting tubule cells: 109.4" "Cell type enhanced" "Detected in all" "midbrain-derived inhibitory: 1859.3" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 17.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 7.7;Neuroblastoma: 9.8;Rhabdoid: 8.7;skin cancer: 8.1" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells, Minor Salivary Gland - Fibroblasts, Stomach - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051535 Approved "Secreted in other tissues" Other NA NA 6000 "Cluster 36: Brain & Liver - Signaling" "Cluster 53: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 109: Neurons - Neuronal signaling" 2 "HPA051535: " "unprognostic (2.01e-1)" "unprognostic (1.51e-1)" "unprognostic (2.03e-2)" "potential prognostic unfavorable (7.16e-5)" "unprognostic (2.33e-1)" "unprognostic (1.65e-1)" "unprognostic (3.11e-1)" "unprognostic (8.14e-2)" "unprognostic (1.06e-1)" "unprognostic (2.16e-1)" "unprognostic (9.24e-2)" "unprognostic (3.10e-2)" "unprognostic (1.30e-1)" "unprognostic (9.19e-2)" NELL2 NRP2 ENSG00000184613 "Neural EGFL like 2" Q99435 12 44508275-44921848 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Neurogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 117.3;choroid plexus: 119.8;retina: 78.9" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 202.1;Brain excitatory neurons: 758.7;Brain inhibitory neurons: 177.0;Choroid plexus epithelial cells: 587.9;Ependymal cells: 497.8;Fallopian tube ciliated cells: 320.4;Lactotrophs: 445.2;Other brain neurons: 206.1;Respiratory ciliated cells: 174.1;Retinal pigment epithelial cells: 567.0;Rod photoreceptor cells: 242.9;Somatotrophs: 308.6;Thyrotrophs: 815.0" "Cell type enhanced" "Detected in all" "hippocampal dentate gyrus: 2044.0" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 99.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 70.6;naive CD8 T-cell: 111.4" "Lineage enriched" "Detected in many" 10 "T-cells: 111.4" "Group enriched" "Detected in many" 5 "Bone cancer: 132.3;Neuroblastoma: 58.4" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Lung - Respiratory ciliated cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Spleen - T-cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035714, HPA035715" Uncertain Approved Vesicles "Secreted to blood" Other NA NA 4100000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 51: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" 11 Vesicles "HPA035714: , HPA035715: " "unprognostic (1.78e-1)" "unprognostic (9.60e-2)" "unprognostic (4.44e-1)" "unprognostic (2.88e-2)" "unprognostic (1.14e-1)" "unprognostic (5.35e-2)" "unprognostic (1.01e-1)" "unprognostic (2.09e-1)" "unprognostic (5.98e-2)" "unprognostic (1.98e-1)" "unprognostic (3.41e-1)" "unprognostic (7.91e-2)" "unprognostic (3.58e-2)" "unprognostic (5.46e-2)" "unprognostic (2.03e-2)" "unprognostic (1.93e-1)" "unprognostic (4.64e-1)" "unprognostic (5.11e-1)" "potential prognostic favorable (2.96e-4)" "unprognostic (6.13e-3)" "unprognostic (4.12e-2)" "unprognostic (2.49e-1)" "unprognostic (3.13e-1)" "unprognostic (1.04e-1)" "unprognostic (1.59e-1)" "unprognostic (1.85e-1)" "unprognostic (9.35e-3)" "unprognostic (1.32e-1)" NEMF "FLJ10051, NY-CO-1, RQC2, SDCCAG1" ENSG00000165525 "Nuclear export mediator factor" O60524 14 49782083-49852821 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Intellectual disability, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004160 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 6300 "Cluster 41: Basophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 7: Non-specific - Transcription" 11 "Nucleoplasm, Cytosol" "Nuclear bodies" "HPA004160: " "unprognostic (9.98e-2)" "unprognostic (7.47e-2)" "unprognostic (2.15e-1)" "unprognostic (4.85e-1)" "unprognostic (7.32e-2)" "unprognostic (3.62e-2)" "unprognostic (3.14e-2)" "unprognostic (1.53e-1)" "unprognostic (5.57e-2)" "validated prognostic favorable (2.51e-7)" "validated prognostic favorable (1.95e-4)" "unprognostic (2.06e-1)" "unprognostic (4.15e-2)" "unprognostic (2.35e-1)" "unprognostic (1.35e-1)" "unprognostic (2.23e-2)" "unprognostic (2.18e-1)" "unprognostic (3.23e-2)" "unprognostic (7.07e-2)" "unprognostic (3.73e-1)" "unprognostic (2.74e-2)" "unprognostic (1.11e-2)" "unprognostic (2.33e-1)" "unprognostic (6.85e-2)" "unprognostic (4.00e-1)" "unprognostic (3.76e-1)" "unprognostic (8.75e-2)" "unprognostic (2.79e-1)" "unprognostic (1.98e-1)" "unprognostic (4.53e-2)" NEMP1 "KIAA0286, TMEM194, TMEM194A" ENSG00000166881 "Nuclear envelope integral membrane protein 1" O14524 12 57055643-57088063 "Predicted membrane proteins, Transporters" "Erythrocyte maturation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 52.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014394 Uncertain Approved Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 49: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 27: Non-specific - Cell proliferation" Nucleoplasm "HPA014394: " "unprognostic (1.04e-1)" "unprognostic (5.83e-2)" "unprognostic (2.96e-1)" "unprognostic (1.09e-1)" "unprognostic (1.90e-2)" "unprognostic (2.06e-1)" "unprognostic (2.86e-1)" "unprognostic (6.43e-2)" "unprognostic (5.30e-3)" "unprognostic (1.15e-1)" "unprognostic (8.28e-2)" "unprognostic (1.60e-2)" "potential prognostic unfavorable (2.58e-5)" "unprognostic (6.06e-3)" "unprognostic (1.02e-1)" "unprognostic (1.26e-1)" "unprognostic (1.67e-2)" "unprognostic (4.17e-1)" "unprognostic (1.48e-1)" "unprognostic (1.86e-1)" "unprognostic (1.55e-2)" "unprognostic (7.46e-2)" "unprognostic (8.36e-2)" "unprognostic (4.77e-3)" "unprognostic (5.64e-3)" "unprognostic (1.40e-1)" "unprognostic (1.67e-1)" "unprognostic (3.31e-2)" "unprognostic (5.07e-2)" NEMP2 TMEM194B ENSG00000189362 "Nuclear envelope integral membrane protein 2" A6NFY4 2 190504338-190534722 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Epicardial cells: 40.9;Thymocytes: 28.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA057719 Approved Nucleoplasm NA NA "Cluster 1: T-cells - Unknown function" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 2: Neurons - Nucleosome" "Cluster 72: Neuronal - Signal transduction" "Cluster 9: T-cells - Adaptive immunity: Regulation" Nucleoplasm "HPA057719: " "unprognostic (8.31e-2)" "unprognostic (1.57e-1)" "unprognostic (1.44e-3)" "potential prognostic unfavorable (1.55e-5)" "unprognostic (1.31e-2)" "unprognostic (8.89e-3)" "unprognostic (2.30e-2)" "unprognostic (6.60e-2)" "unprognostic (1.26e-2)" "potential prognostic favorable (2.64e-5)" "unprognostic (1.43e-2)" "unprognostic (2.07e-2)" "potential prognostic unfavorable (3.03e-5)" "unprognostic (1.78e-2)" "unprognostic (2.73e-2)" "unprognostic (2.89e-1)" "unprognostic (4.11e-1)" "unprognostic (1.44e-1)" "unprognostic (3.76e-2)" "potential prognostic unfavorable (8.31e-6)" "unprognostic (5.96e-2)" "unprognostic (2.17e-1)" "unprognostic (2.61e-1)" "unprognostic (5.59e-2)" "unprognostic (8.59e-2)" "unprognostic (1.62e-1)" "unprognostic (1.95e-1)" "unprognostic (3.60e-2)" NENF "CIR2, SCIRP10, SPUF" ENSG00000117691 "Neudesin neurotrophic factor" Q9UMX5 1 212432920-212446379 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Gastric progenitor cells: 433.2" "Cell type enhanced" "Detected in all" "oligodendrocyte: 164.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026763, HPA028488" Uncertain "Secreted to blood" "No annotated function" NA NA 5000000 "Cluster 13: Non-specific - Mitochondria" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 27: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 1 "HPA026763: , HPA028488: " "unprognostic (3.99e-1)" "unprognostic (1.86e-2)" "unprognostic (8.02e-2)" "unprognostic (9.22e-2)" "unprognostic (1.23e-2)" "unprognostic (2.57e-2)" "unprognostic (6.18e-2)" "unprognostic (8.92e-2)" "unprognostic (3.40e-2)" "unprognostic (6.73e-2)" "unprognostic (1.73e-3)" "unprognostic (3.09e-2)" "unprognostic (1.09e-1)" "unprognostic (5.09e-3)" "unprognostic (7.16e-3)" "unprognostic (2.07e-1)" "unprognostic (1.70e-1)" "unprognostic (3.97e-1)" "unprognostic (1.49e-1)" "unprognostic (2.73e-1)" "unprognostic (3.80e-1)" "unprognostic (1.67e-3)" "unprognostic (7.52e-2)" "unprognostic (3.84e-2)" "unprognostic (7.12e-3)" "unprognostic (1.94e-1)" "unprognostic (8.24e-2)" "unprognostic (2.69e-2)" "unprognostic (2.22e-1)" "unprognostic (1.03e-1)" "unprognostic (5.98e-2)" NEO1 "HsT17534, IGDCC2, NGN, NTN1R2" ENSG00000067141 "Neogenin 1" Q92859 15 73051710-73305205 "Cancer-related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 371.6;Bergmann glia: 368.6;Myonuclei: 631.1;Oligodendrocytes: 518.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009320, HPA027804, HPA027805, HPA027806" Uncertain Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA 65000000 "Cluster 77: Intestine - Digestion" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 3 "Nucleoplasm, Plasma membrane" "Golgi apparatus" "CAB009320: , HPA027804: , HPA027805: , HPA027806: " "unprognostic (1.40e-1)" "unprognostic (1.67e-1)" "unprognostic (1.26e-1)" "unprognostic (2.38e-2)" "unprognostic (1.59e-2)" "unprognostic (2.77e-1)" "unprognostic (1.97e-1)" "unprognostic (1.12e-1)" "unprognostic (3.34e-2)" "unprognostic (1.58e-1)" "potential prognostic favorable (2.83e-8)" "unprognostic (7.53e-3)" "unprognostic (2.03e-1)" "unprognostic (2.05e-2)" "unprognostic (1.05e-1)" "unprognostic (2.02e-1)" "unprognostic (1.34e-1)" "unprognostic (1.28e-1)" "unprognostic (1.88e-3)" "unprognostic (5.96e-2)" "unprognostic (1.85e-1)" "unprognostic (1.04e-1)" "unprognostic (1.76e-3)" "unprognostic (1.54e-1)" "unprognostic (4.96e-2)" "unprognostic (5.61e-3)" "unprognostic (4.36e-1)" "unprognostic (1.53e-1)" "unprognostic (1.49e-1)" "unprognostic (3.22e-2)" "unprognostic (2.78e-1)" NEPRO "C3orf17, DKFZP434F2021, NET17" ENSG00000163608 "Nucleolus and neural progenitor protein" Q6NW34 3 113002444-113019861 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069654 Supported Nucleoplasm,Nucleoli Yes No "Cluster 24: Non-specific - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 21 "Nucleoplasm, Nucleoli" "HPA069654: " "unprognostic (1.33e-1)" "unprognostic (2.23e-1)" "unprognostic (1.93e-1)" "unprognostic (2.01e-3)" "unprognostic (1.83e-1)" "unprognostic (1.17e-1)" "unprognostic (1.16e-2)" "unprognostic (5.59e-2)" "unprognostic (1.32e-1)" "potential prognostic favorable (2.09e-5)" "unprognostic (2.51e-1)" "unprognostic (2.03e-2)" "unprognostic (7.40e-3)" "unprognostic (1.81e-1)" "unprognostic (4.21e-1)" "unprognostic (1.74e-1)" "unprognostic (5.04e-2)" "unprognostic (1.35e-2)" "unprognostic (1.18e-1)" "unprognostic (5.57e-2)" "unprognostic (7.07e-3)" "unprognostic (9.48e-2)" "unprognostic (1.09e-2)" "unprognostic (3.46e-2)" "unprognostic (1.10e-1)" "unprognostic (2.46e-1)" "unprognostic (9.84e-2)" "unprognostic (2.60e-1)" "unprognostic (1.01e-1)" NES FLJ21841 ENSG00000132688 Nestin P48681 1 156668763-156677407 "Plasma proteins, Predicted intracellular proteins" Neurogenesis "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 151.3" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 83.5;Endometrial stromal cells: 25.9;Hepatic stellate cells: 64.5;Pericytes: 77.3;Podocytes: 141.2;Schwann cells: 81.1;Smooth muscle cells: 51.8;Vascular endothelial cells: 101.7;Vascular smooth muscle cells: 55.9" "Cell type enhanced" "Detected in many" "Bergmann glia: 29.3;endothelial cell: 73.9;vascular associated smooth muscle cell: 32.0" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 240.1;Skin Cutaneous Melanoma (TCGA): 186.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 313.9" "Adipose subcutaneous - Endothelial cells, Minor Salivary Gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005889, HPA006286, HPA007007, HPA026111, CAB058692" Enhanced Enhanced "Intermediate filaments" No No 51000 "Cluster 35: Non-specific - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 21 "Intermediate filaments" "CAB005889: , CAB058692: , HPA006286: , HPA007007: , HPA026111: " "unprognostic (3.27e-1)" "unprognostic (8.59e-2)" "unprognostic (4.76e-2)" "unprognostic (2.42e-2)" "unprognostic (1.32e-1)" "unprognostic (2.33e-1)" "unprognostic (1.51e-1)" "unprognostic (4.38e-3)" "unprognostic (1.92e-1)" "unprognostic (8.46e-3)" "validated prognostic favorable (1.50e-4)" "validated prognostic favorable (7.83e-4)" "unprognostic (3.47e-3)" "unprognostic (2.39e-2)" "unprognostic (2.59e-1)" "unprognostic (1.88e-2)" "unprognostic (2.65e-2)" "unprognostic (6.04e-2)" "unprognostic (2.02e-1)" "unprognostic (1.81e-1)" "unprognostic (3.50e-1)" "unprognostic (4.69e-2)" "unprognostic (1.83e-2)" "unprognostic (7.60e-2)" "unprognostic (1.47e-1)" "unprognostic (3.42e-2)" "unprognostic (1.23e-1)" "unprognostic (1.16e-1)" "unprognostic (2.30e-1)" "unprognostic (5.08e-2)" "unprognostic (1.74e-2)" NET1 "ARHGEF8, NET1A" ENSG00000173848 "Neuroepithelial cell transforming 1" Q7Z628 10 5412557-5459056 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 776.6;Ocular epithelial cells: 425.3" "Group enriched" "Detected in all" 4 "choroid plexus epithelial cell: 218.3;endothelial cell: 415.6;vascular associated smooth muscle cell: 219.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 8.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Liver - Hepatocytes, Spleen - Mitotic cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020068 Uncertain Approved Nucleoplasm,Vesicles Yes Yes "Cluster 31: T-cells - T-cell receptor" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 9 Nucleoplasm Vesicles "HPA020068: " "unprognostic (7.70e-2)" "unprognostic (3.26e-3)" "potential prognostic favorable (4.80e-4)" "unprognostic (1.01e-1)" "unprognostic (1.86e-1)" "unprognostic (8.53e-3)" "unprognostic (1.39e-1)" "potential prognostic favorable (2.28e-4)" "unprognostic (1.94e-1)" "unprognostic (4.49e-2)" "potential prognostic favorable (2.20e-5)" "unprognostic (2.26e-3)" "unprognostic (6.78e-2)" "potential prognostic unfavorable (5.63e-5)" "unprognostic (1.08e-3)" "unprognostic (1.28e-1)" "potential prognostic unfavorable (7.99e-4)" "unprognostic (9.67e-3)" "unprognostic (4.25e-2)" "unprognostic (2.91e-2)" "unprognostic (5.22e-3)" "potential prognostic unfavorable (3.55e-4)" "unprognostic (2.15e-1)" "unprognostic (2.44e-1)" "unprognostic (4.71e-2)" "unprognostic (2.91e-1)" "unprognostic (2.31e-1)" "unprognostic (1.03e-1)" "unprognostic (9.60e-2)" "unprognostic (1.67e-1)" "unprognostic (4.32e-2)" NETO1 "BCTL1, BTCL1" ENSG00000166342 "Neuropilin and tolloid like 1" Q8TDF5 18 72742314-72868146 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 12 "brain: 25.4;retina: 32.0" "Cell type enhanced" "Detected in some" "B-cells: 91.9;Brain excitatory neurons: 195.1;Brain inhibitory neurons: 333.4;Oligodendrocyte progenitor cells: 191.0;Other brain neurons: 59.6;Retinal bipolar cells: 1084.1" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 4.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 7 "prostate cancer: 64.5" "Spleen - B-cells (Spleen), Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA064630 Approved "Golgi apparatus" "Secreted in brain" Receptor NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "Golgi apparatus" "HPA064630: " "unprognostic (9.10e-2)" "unprognostic (1.26e-1)" "potential prognostic favorable (2.48e-4)" "unprognostic (1.40e-2)" "unprognostic (2.97e-2)" "unprognostic (4.25e-2)" "unprognostic (1.73e-1)" NETO2 "FLJ10430, NEOT2" ENSG00000171208 "Neuropilin and tolloid like 2" Q8NC67 16 47077703-47143945 "Predicted membrane proteins, Transporters" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.9;lymphoid tissue: 21.4" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 83.2;Brain inhibitory neurons: 203.6;cDC: 75.2;Choroid plexus epithelial cells: 71.6;Early primary spermatocytes: 82.5;Monocyte progenitors: 96.9;monocytes: 87.5;Müller glia: 92.9;Oligodendrocyte progenitor cells: 92.1;Retinal amacrine cells: 78.8;Retinal pigment epithelial cells: 230.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013180 Uncertain Approved "Golgi apparatus" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 24: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Neurons - Synaptic function & neurogenesis" 1 "Golgi apparatus" "HPA013180: " "unprognostic (3.95e-1)" "unprognostic (1.39e-2)" "unprognostic (6.43e-2)" "unprognostic (1.17e-1)" "unprognostic (3.30e-1)" "unprognostic (2.60e-1)" "unprognostic (3.65e-1)" "unprognostic (2.31e-2)" "unprognostic (3.15e-3)" "unprognostic (6.07e-3)" "potential prognostic favorable (5.16e-4)" "unprognostic (9.90e-2)" "potential prognostic unfavorable (3.60e-6)" "unprognostic (9.56e-3)" "unprognostic (3.36e-1)" "unprognostic (1.36e-3)" "potential prognostic unfavorable (8.17e-4)" "unprognostic (1.35e-1)" "unprognostic (1.84e-2)" "unprognostic (1.14e-1)" "unprognostic (1.34e-1)" "unprognostic (3.09e-2)" "unprognostic (3.73e-1)" "unprognostic (2.08e-1)" "unprognostic (8.13e-2)" "unprognostic (2.42e-1)" "unprognostic (2.97e-2)" "unprognostic (4.61e-3)" "unprognostic (7.54e-2)" "unprognostic (2.35e-2)" "unprognostic (6.06e-2)" NEU1 NEU ENSG00000204386 "Neuraminidase 1" Q99519 6 31857659-31862905 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Lipid degradation, Lipid metabolism" "Glycosidase, Hydrolase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 8.0;Brain excitatory neurons: 10.3;Brain inhibitory neurons: 9.1;Distal convoluted tubule cells: 10.7;Ependymal cells: 7.0;Loop of henle epithelial cells: 9.7;Microglia: 9.2;Oligodendrocyte progenitor cells: 8.5;Other brain neurons: 14.8;Papillary tip epithelial cells: 15.3;Proximal tubule cells: 10.0;Renal collecting duct intercalated cells: 7.4;Renal collecting duct principal cells: 11.1;Renal connecting tubule cells: 7.6" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 5.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 3.0" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.0" "Low cancer specificity" "Detected in some" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015634, HPA021506" Approved Supported "Vesicles,Cell Junctions" NA NA 180000 "Cluster 20: Non-specific - DNA binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 15: Non-specific - Transcription" "Cluster 20: Myeloma - Immune response" "Cluster 98: Neurons - Neurotransmission & signaling" 28 Vesicles "Cell Junctions" "HPA015634: , HPA021506: " "unprognostic (6.33e-2)" "unprognostic (6.98e-2)" "unprognostic (1.27e-1)" "unprognostic (4.91e-3)" "potential prognostic favorable (4.57e-5)" "unprognostic (1.22e-3)" "unprognostic (2.14e-1)" "potential prognostic unfavorable (4.89e-5)" "unprognostic (3.09e-2)" "unprognostic (1.93e-1)" "unprognostic (4.64e-2)" "unprognostic (1.25e-1)" "unprognostic (1.42e-1)" "unprognostic (1.83e-1)" "unprognostic (3.45e-1)" "unprognostic (2.75e-2)" "unprognostic (3.61e-1)" NEU2 SIAL2 ENSG00000115488 "Neuraminidase 2" Q9Y3R4 2 233032672-233035057 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Lipid degradation, Lipid metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 19 "skin 1: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Skin - Inner root sheath cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in single" "cerebral cortex: 1.5" CAB022336 Uncertain NA NA "Cluster 37: Skin - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" 14 "CAB022336: " NEU3 ENSG00000162139 "Neuraminidase 3" Q9UQ49 11 74988279-75018893 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Lipid degradation, Lipid metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 53.0;Cone photoreceptor cells: 84.9;Early primary spermatocytes: 52.5;Myonuclei: 90.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038729, HPA070381" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 9: Non-specific - Receptor signaling" "Cluster 24: Non-specific - Unknown function" "Cluster 55: Myocytes - Oxidative muscle function" 5 Nucleoplasm Vesicles "HPA038729: , HPA070381: " "unprognostic (9.56e-2)" "unprognostic (8.81e-2)" "unprognostic (3.02e-1)" "unprognostic (8.22e-2)" "unprognostic (1.97e-1)" "unprognostic (4.76e-2)" "unprognostic (2.67e-1)" "potential prognostic favorable (2.40e-4)" "unprognostic (1.94e-1)" "unprognostic (4.29e-3)" "unprognostic (1.09e-1)" "unprognostic (2.82e-1)" "unprognostic (1.04e-1)" "unprognostic (1.36e-2)" "unprognostic (2.16e-2)" "unprognostic (1.65e-1)" "unprognostic (6.76e-3)" "unprognostic (3.97e-3)" "unprognostic (1.80e-1)" "unprognostic (3.01e-2)" "unprognostic (9.18e-2)" "unprognostic (4.42e-3)" "potential prognostic unfavorable (8.99e-4)" "unprognostic (9.63e-3)" "potential prognostic favorable (9.29e-5)" "unprognostic (4.38e-3)" "unprognostic (2.77e-2)" "unprognostic (2.47e-1)" "unprognostic (7.91e-2)" "unprognostic (9.52e-2)" "unprognostic (1.54e-1)" NEU4 ENSG00000204099 "Neuraminidase 4" Q8WWR8 2 241809065-241817413 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Lipid degradation, Lipid metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 78.7" "Cell type enriched" "Detected in some" 9 "Oligodendrocyte progenitor cells: 84.8" "Group enriched" "Detected in many" 14 "committed oligodendrocyte precursor: 57.8;oligodendrocyte precursor cell: 112.8" "Group enriched" "Detected in some" 5 "Glioblastoma Multiforme (TCGA): 9.6;Liver Hepatocellular Carcinoma (TCGA): 17.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 3.2;liver cancer: 8.6" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Kidney - Ascending Loop of Henle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037394 Enhanced NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 10 "HPA037394: " "unprognostic (1.94e-1)" "unprognostic (3.47e-2)" "unprognostic (4.40e-3)" "unprognostic (9.87e-3)" "potential prognostic favorable (8.39e-4)" "unprognostic (7.67e-2)" "unprognostic (4.89e-3)" "unprognostic (1.54e-1)" "unprognostic (2.13e-1)" "potential prognostic unfavorable (8.94e-4)" NEURL1 "h-neu, neu-1, NEURL, RNF67" ENSG00000107954 "Neuralized E3 ubiquitin protein ligase 1" O76050 10 103493705-103592546 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Notch signaling pathway, Translation regulation, Ubl conjugation pathway" Transferase "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 63.3;skeletal muscle: 136.2;tongue: 55.8" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 296.0;Early spermatids: 209.5;Goblet cells: 197.5;Late spermatids: 788.9;Retinal bipolar cells: 190.9;Rod photoreceptor cells: 379.7;Salivary ionocytes: 212.1;Syncytiotrophoblasts: 240.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 13 "intermediate monocyte: 44.8;non-classical monocyte: 111.7" "Lineage enriched" "Detected in many" 19 "monocytes: 111.7" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal medulla cells, Colon - Colon enterocytes, Stomach - Gastric enteroendocrine cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044204 Enhanced NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 51: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 70: Intestinal goblet cells - Mucin production" 2 "HPA044204: " "unprognostic (1.03e-1)" "unprognostic (4.62e-2)" "unprognostic (3.78e-2)" "potential prognostic favorable (1.04e-4)" "unprognostic (9.03e-2)" "unprognostic (9.29e-3)" "unprognostic (1.99e-2)" "unprognostic (1.51e-1)" "unprognostic (3.80e-2)" "unprognostic (9.57e-3)" "unprognostic (1.02e-1)" "unprognostic (1.55e-1)" "unprognostic (1.94e-1)" "unprognostic (1.34e-1)" "unprognostic (3.72e-3)" "unprognostic (3.50e-2)" "unprognostic (8.29e-2)" "unprognostic (2.40e-3)" "unprognostic (1.86e-1)" "unprognostic (1.11e-1)" "unprognostic (6.20e-3)" "potential prognostic unfavorable (2.36e-4)" "unprognostic (4.37e-2)" "unprognostic (1.79e-1)" "unprognostic (1.18e-1)" "unprognostic (6.83e-3)" NEURL1B "DKFZP761M1511, Neur2, RNF67B" ENSG00000214357 "Neuralized E3 ubiquitin protein ligase 1B" A8MQ27 5 172641263-172691540 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Notch signaling pathway, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Colonocytes: 94.7;Enterocytes: 74.9;Hepatic stellate cells: 142.0;Leydig cells: 117.6;Pericytes: 196.4;Tuft cells: 103.8;Vascular endothelial cells: 108.4;Vascular smooth muscle cells: 105.1" "Cell type enhanced" "Detected in many" "pericyte: 127.2;vascular associated smooth muscle cell: 206.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Adrenal gland - Fibroblasts, Breast - Endothelial cells, Minor Salivary Gland - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA037612 Approved Supported "Actin filaments,Cytosol" NA Yes "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 29: Forebrain - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 110: Mural cells - ECM organization" Cytosol "Actin filaments" "HPA037612: " "unprognostic (1.15e-2)" "unprognostic (7.18e-3)" "unprognostic (3.67e-1)" "unprognostic (4.55e-1)" "unprognostic (8.51e-2)" "unprognostic (7.10e-2)" "unprognostic (1.78e-1)" "unprognostic (1.33e-2)" "unprognostic (1.21e-1)" "unprognostic (1.55e-2)" "potential prognostic favorable (2.17e-4)" "unprognostic (2.05e-3)" "potential prognostic unfavorable (3.97e-8)" "unprognostic (5.34e-2)" "unprognostic (4.60e-1)" "unprognostic (1.11e-1)" "unprognostic (5.15e-2)" "unprognostic (6.25e-2)" "unprognostic (7.29e-2)" "unprognostic (1.03e-1)" "unprognostic (6.16e-2)" "unprognostic (1.39e-2)" "unprognostic (1.39e-1)" "unprognostic (2.13e-2)" "unprognostic (1.20e-1)" "unprognostic (6.61e-2)" "unprognostic (1.33e-1)" "unprognostic (2.76e-1)" "unprognostic (1.05e-1)" "unprognostic (8.90e-2)" "unprognostic (3.48e-3)" NEURL2 "C20orf163, dJ337O18.6, FLJ30259, Ozz, Ozz-E3" ENSG00000124257 "Neuralized E3 ubiquitin protein ligase 2" Q9BR09 20 45888625-45891208 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal basal cells: 20.4;Hofbauer cells: 62.3;Kupffer cells: 33.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043402, HPA059842" Approved Approved Vesicles NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 72: Kidney - Transmembrane transport" "Cluster 15: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 1 Vesicles "HPA043402: , HPA059842: " "unprognostic (1.14e-2)" "unprognostic (4.91e-2)" "unprognostic (6.87e-2)" "potential prognostic favorable (1.84e-4)" "unprognostic (3.03e-1)" "unprognostic (3.91e-1)" "unprognostic (1.38e-2)" "unprognostic (1.51e-2)" "unprognostic (7.45e-2)" "unprognostic (1.43e-2)" "unprognostic (3.75e-2)" "unprognostic (2.93e-2)" "potential prognostic favorable (8.59e-4)" "potential prognostic unfavorable (2.86e-4)" "unprognostic (5.12e-2)" "unprognostic (5.40e-1)" "unprognostic (1.12e-1)" "unprognostic (1.61e-1)" "unprognostic (1.60e-1)" "unprognostic (1.20e-1)" "unprognostic (2.42e-1)" "potential prognostic favorable (7.05e-4)" "unprognostic (9.63e-2)" "unprognostic (3.37e-1)" "potential prognostic favorable (1.13e-5)" "unprognostic (1.55e-3)" "unprognostic (4.75e-3)" "unprognostic (8.48e-2)" "unprognostic (1.36e-1)" "unprognostic (2.68e-2)" "unprognostic (1.56e-1)" NEURL3 "Lincr, LOC93082, RNF132" ENSG00000163121 "Neuralized E3 ubiquitin protein ligase 3" Q96EH8 2 96497646-96508109 "Enzymes, Predicted intracellular proteins" "Host-virus interaction, Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "kidney: 15.2;pancreas: 24.5;salivary gland: 28.5" "Cell type enhanced" "Detected in some" "Cholangiocytes: 21.0;Conjunctival goblet cells: 35.0;Lacrimal acinar cells: 50.7;Pancreatic acinar cells: 18.1;Pancreatic duct cells: 181.3;Salivary duct cells: 97.6" "Cell type enhanced" "Detected in single" "endothelial cell: 3.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Uterine cancer: 8.6" "Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in some" "Not detected" "Not detected" NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 53: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 4 "unprognostic (1.50e-1)" "unprognostic (4.35e-2)" "unprognostic (1.19e-1)" "unprognostic (1.52e-1)" "unprognostic (3.85e-1)" "unprognostic (2.35e-2)" "unprognostic (2.55e-2)" "unprognostic (2.11e-1)" "unprognostic (1.40e-2)" "unprognostic (2.29e-1)" "unprognostic (7.85e-2)" "unprognostic (3.31e-2)" "unprognostic (3.14e-3)" "potential prognostic unfavorable (4.56e-4)" "unprognostic (3.33e-3)" "unprognostic (1.25e-1)" "unprognostic (1.44e-1)" "unprognostic (1.57e-1)" "unprognostic (4.67e-2)" "unprognostic (2.26e-1)" "unprognostic (3.76e-2)" "unprognostic (2.27e-1)" "unprognostic (1.05e-2)" "unprognostic (1.86e-1)" "unprognostic (1.87e-1)" "unprognostic (1.02e-1)" "unprognostic (2.06e-1)" NEURL4 KIAA1787 ENSG00000215041 "Neuralized E3 ubiquitin protein ligase 4" Q96JN8 17 7315628-7329393 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 11.0;Bergmann glia: 7.8;Brain excitatory neurons: 9.7;Brain inhibitory neurons: 9.7;Choroid plexus epithelial cells: 7.7;Ependymal cells: 7.5;Microglia: 7.9;Oligodendrocyte progenitor cells: 7.1;Oligodendrocytes: 8.6;Other brain neurons: 7.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043678, HPA055314" Uncertain NA NA "Cluster 24: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 22: Non-specific - Basic cellular functions" 21 "HPA043678: , HPA055314: " "unprognostic (4.75e-2)" "unprognostic (2.24e-2)" "unprognostic (4.21e-1)" "unprognostic (2.08e-1)" "unprognostic (9.96e-2)" "unprognostic (9.94e-3)" "unprognostic (3.47e-1)" "unprognostic (4.41e-3)" "unprognostic (3.90e-3)" "unprognostic (6.22e-2)" "unprognostic (1.50e-3)" "unprognostic (6.76e-3)" "unprognostic (2.86e-3)" "unprognostic (8.39e-2)" "unprognostic (9.92e-2)" "unprognostic (3.68e-1)" "unprognostic (1.96e-1)" "unprognostic (1.05e-2)" "unprognostic (1.03e-2)" "unprognostic (2.62e-2)" "unprognostic (8.64e-3)" "unprognostic (1.06e-2)" "unprognostic (1.43e-1)" "unprognostic (3.12e-2)" "unprognostic (1.06e-1)" "unprognostic (1.33e-1)" "unprognostic (3.19e-2)" "unprognostic (2.61e-1)" "unprognostic (9.06e-2)" "unprognostic (1.58e-1)" NEUROD1 "BETA2, BHF-1, bHLHa3, MODY6, NEUROD" ENSG00000162992 "Neuronal differentiation 1" Q13562 2 181668295-181680827 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "brain: 166.9;retina: 131.5" "Group enriched" "Detected in some" 6 "Neuroendocrine cells: 66.8;Rod photoreceptor cells: 24.4" "Cell type enriched" "Detected in some" 9 "upper rhombic lip: 14.2" "Group enriched" "Detected in some" 5 "Glioblastoma Multiforme (TCGA): 4.2;Lung Adenocarcinoma (TCGA): 2.4;Pancreatic Adenocarcinoma (TCGA): 8.3;Stomach Adenocarcinoma (TCGA): 2.2" "Region enriched" "Detected in all" 6 "cerebellum: 149.5" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in some" "lung cancer: 18.9;Neuroblastoma: 16.4" "Pancreas - Alpha cells, Pancreas - Beta cells, Stomach - Gastric enteroendocrine cells, Testis - Early spermatids" "Region enriched" "Detected in all" 14 "cerebellum: 216.2" "Region enriched" "Detected in many" 20 "cerebellum: 290.8" "HPA003278, CAB022450" Approved NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 35: Non-specific - DNA binding" "Cluster 1: Neuronal - Visual perception" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" 14 "CAB022450: , HPA003278: " "validated prognostic favorable (5.32e-5)" "validated prognostic favorable (5.36e-4)" "unprognostic (2.21e-2)" "unprognostic (3.25e-1)" "unprognostic (3.50e-3)" "unprognostic (4.05e-2)" "unprognostic (1.03e-1)" NEUROD2 "bHLHa1, NDRF" ENSG00000171532 "Neuronal differentiation 2" Q15784 17 39603536-39609777 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 131 "brain: 99.0" "Group enriched" "Detected in some" 4 "Brain excitatory neurons: 38.2;Neuroendocrine cells: 11.0" "Cell type enhanced" "Detected in many" "upper rhombic lip: 59.8" "Cancer enhanced" "Detected in some" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 3.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lung cancer: 1.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 11 "amygdala: 28.7;cerebellum: 96.3;cerebral cortex: 52.8;hippocampal formation: 103.6" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 37: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 35: Neurons - Synaptic function & neurogenesis" 1 "unprognostic (1.19e-1)" "unprognostic (3.20e-2)" "unprognostic (2.41e-1)" "unprognostic (2.86e-1)" NEUROD4 "ATH-3, Atoh3, bHLHa4, MATH-3" ENSG00000123307 "Neuronal differentiation 4" Q9HD90 12 55019974-55030017 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "pituitary gland: 7.7;retina: 28.0" "Cell type enhanced" "Detected in some" "Gonadotrophs: 88.4;Lactotrophs: 50.3;Retinal bipolar cells: 172.1;Somatotrophs: 47.0;Thyrotrophs: 31.9" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "choroid plexus: 1.2;hypothalamus: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "lung cancer: 1.5;Neuroblastoma: 1.5;Uterine cancer: 1.1" "Adrenal gland - Adrenal medulla cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015545, HPA026998, HPA055750" Enhanced Supported Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 42: Retina - Visual perception" "Cluster 36: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 2 Nucleoplasm "Centrosome, Cytosol" "HPA015545: , HPA026998: , HPA055750: " "potential prognostic favorable (3.77e-4)" NEUROD6 "Atoh2, bHLHa2, Math-2, Nex1, NEX1M" ENSG00000164600 "Neuronal differentiation 6" Q96NK8 7 31337465-31340726 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 135 "brain: 39.1" "Cell type enriched" "Detected in some" 10 "Brain excitatory neurons: 23.0" "Cell type enhanced" "Detected in many" "hippocampal CA4: 180.7;miscellaneous: 71.6" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "basal ganglia: 20.0;cerebral cortex: 22.3;hippocampal formation: 51.2;white matter: 13.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 27 "Bone cancer: 17.2" "Region enhanced" "Detected in all" "hippocampal formation: 225.2" "Group enriched" "Detected in many" 9 "cerebral cortex: 27.4;hippocampal formation: 106.8" HPA074530 Enhanced NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" "HPA074530: " "unprognostic (1.84e-1)" NEUROG1 "AKA, bHLHa6, Math4C, NEUROD3, ngn1" ENSG00000181965 "Neurogenin 1" Q92886 5 135534282-135535964 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Deafness, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 7 "Oocytes: 50.7" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 12 "Testicular Germ Cell Tumor (TCGA): 1.8" "Group enriched" "Detected in some" 12 "choroid plexus: 1.1;hypothalamus: 1.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Brain cancer: 2.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA072232 Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 36: Choroid plexus - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 10 Nucleoplasm "Nuclear bodies" "HPA072232: " "unprognostic (1.14e-1)" NEUROG2 "Atoh4, bHLHa8, Math4A, ngn-2, NGN2" ENSG00000178403 "Neurogenin 2" Q9H2A3 4 112513516-112516180 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.1;testis: 1.5" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 6.0;Early spermatids: 2.0;Late primary spermatocytes: 2.9;Late spermatids: 1.6;Müller glia: 8.4" "Cell type enhanced" "Detected in some" "cerebellar inhibitory: 14.1;hippocampal CA4: 4.2" "Cancer enhanced" "Detected in single" "Uterine Corpus Endometrial Carcinoma (TCGA): 1.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 9 "Neuroblastoma: 15.0" "Testis - Early spermatids" "Low region specificity" "Detected in single" "Region enriched" "Detected in some" 10 "hippocampal formation: 16.2" CAB012342 Uncertain NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 29: Forebrain - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 11: Muller glia cells - Retinal homeostasis" 1 "CAB012342: " "unprognostic (8.42e-2)" "unprognostic (2.57e-1)" NEUROG3 "Atoh5, bHLHa7, Math4B, ngn3" ENSG00000122859 "Neurogenin 3" Q9Y4Z2 10 69571698-69573422 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "brain: 2.3;intestine: 2.4" "Cell type enhanced" "Detected in single" "Neuroendocrine cells: 2.7" "Group enriched" "Detected in some" 11 "hippocampal CA4: 6.9;hippocampal dentate gyrus: 2.8" "Cancer enhanced" "Detected in single" "Stomach Adenocarcinoma (TCGA): 1.9" "Group enriched" "Detected in some" 16 "cerebral cortex: 9.5;hippocampal formation: 11.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "prostate cancer: 6.3" "Adipose visceral - Macrophages, Adrenal gland - Macrophages, Kidney - Macrophages" "Not detected" "Not detected" "Not detected" "Not detected" HPA039785 Uncertain Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 29: Forebrain - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 35: Neurons - Synaptic function & neurogenesis" 54 "Nuclear speckles" Nucleoplasm "HPA039785: " "unprognostic (6.80e-3)" NEXMIF "KIAA2022, KIDLIA, MRX98, XPN" ENSG00000050030 "Neurite extension and migration factor" Q5QGS0 X 74732856-74925472 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" "Developmental protein" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.9" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 127.3;Brain inhibitory neurons: 157.0;Corticotrophs: 114.9;Distal convoluted tubule cells: 120.5;Gonadotrophs: 103.5;Lactotrophs: 187.4;Oligodendrocyte progenitor cells: 98.0;Other brain neurons: 155.8;Retinal amacrine cells: 129.1;Somatotrophs: 291.6;Thyrotrophs: 159.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 1.6;Neuroblastoma: 1.3" "Adipose subcutaneous - Smooth muscle cells, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Somatotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000407 Uncertain Supported Nucleoplasm,Midbody,Cytosol Yes NA "Cluster 73: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 11: Neuronal - Sensory perception" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 1 Nucleoplasm "Midbody, Cytosol" "HPA000407: " "unprognostic (1.83e-1)" "unprognostic (6.97e-2)" "unprognostic (1.07e-1)" NEXN "NELIN, nexilin" ENSG00000162614 "Nexilin F-actin binding protein" Q0ZGT2 1 77888513-77943895 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 378.9;skeletal muscle: 633.7;tongue: 512.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 889.8;Hepatic stellate cells: 548.7;Megakaryocytes: 506.9;Myonuclei: 2709.1;Peritubular myoid cells: 454.0;Platelets: 1327.1;Smooth muscle cells: 498.8;Thymic myoid cells: 1332.4;Vascular smooth muscle cells: 519.5" "Cell type enhanced" "Detected in all" "vascular associated smooth muscle cell: 154.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Colon - Smooth muscle cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Smooth muscle cells" "Region enhanced" "Detected in all" "basal ganglia: 40.4" "Group enriched" "Detected in all" 5 "basal ganglia: 12.3;midbrain: 18.6;pons: 13.6;thalamus: 34.4" "HPA011185, HPA011904" Approved Supported "Plasma membrane,Actin filaments" NA NA 4500000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 11 "Plasma membrane, Actin filaments" "HPA011185: , HPA011904: " "unprognostic (3.22e-3)" "unprognostic (1.15e-1)" "unprognostic (8.55e-2)" "unprognostic (1.74e-1)" "unprognostic (1.28e-2)" "unprognostic (4.95e-2)" "unprognostic (1.09e-1)" "unprognostic (7.03e-2)" "unprognostic (5.98e-3)" "unprognostic (2.04e-1)" "unprognostic (2.02e-2)" "unprognostic (1.65e-1)" "unprognostic (3.76e-2)" "unprognostic (6.85e-3)" "unprognostic (2.70e-2)" "unprognostic (1.98e-1)" "unprognostic (1.06e-1)" "unprognostic (8.83e-2)" "unprognostic (1.68e-1)" "unprognostic (3.44e-2)" "potential prognostic unfavorable (9.90e-4)" "unprognostic (9.60e-2)" "unprognostic (2.13e-1)" "unprognostic (1.32e-1)" "unprognostic (4.75e-2)" "unprognostic (7.05e-3)" "unprognostic (2.14e-2)" "unprognostic (2.03e-1)" "unprognostic (8.26e-3)" "unprognostic (3.13e-2)" NF1 ENSG00000196712 "Neurofibromin 1" P21359 17 31094927-31382116 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "GTPase activation" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells, Spleen - Endothelial cells, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045502, HPA075627, CAB080363, CAB080365" Uncertain Supported "Nucleoplasm,Plasma membrane,Microtubules" NA No "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 25 "Plasma membrane" "Nucleoplasm, Microtubules" "CAB080363: , CAB080365: , HPA045502: , HPA075627: " "unprognostic (1.75e-1)" "unprognostic (4.11e-2)" "unprognostic (2.46e-1)" "unprognostic (4.14e-3)" "unprognostic (6.12e-2)" "unprognostic (1.98e-1)" "unprognostic (2.38e-2)" "unprognostic (1.38e-1)" "unprognostic (5.80e-2)" "unprognostic (1.44e-2)" "potential prognostic favorable (2.97e-4)" "unprognostic (1.54e-2)" "unprognostic (1.82e-1)" "unprognostic (1.46e-1)" "unprognostic (2.67e-2)" "unprognostic (6.20e-2)" "unprognostic (4.16e-2)" "unprognostic (1.35e-1)" "unprognostic (1.37e-2)" "unprognostic (1.65e-2)" "unprognostic (7.41e-2)" "unprognostic (1.17e-2)" "unprognostic (2.53e-3)" "unprognostic (6.64e-2)" "unprognostic (6.89e-3)" "unprognostic (5.77e-2)" "unprognostic (1.63e-1)" "unprognostic (6.77e-2)" "unprognostic (1.90e-1)" "unprognostic (5.34e-2)" "unprognostic (1.19e-1)" NF2 "ACN, BANF, merlin, merlin-1, SCH" ENSG00000186575 "NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor" P35240 22 29603556-29698598 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Deafness, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 176.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003097, CAB005385" Supported Enhanced "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 52: Non-specific - Cellular respiration" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 17: Non-specific - RNA processing" 64 "Plasma membrane" "Nucleoplasm, Cytosol" "CAB005385: , HPA003097: " "unprognostic (4.47e-1)" "unprognostic (1.10e-1)" "unprognostic (9.08e-2)" "unprognostic (1.45e-1)" "unprognostic (1.60e-2)" "unprognostic (3.34e-1)" "unprognostic (2.26e-1)" "unprognostic (1.17e-2)" "unprognostic (1.60e-1)" "unprognostic (9.40e-2)" "potential prognostic favorable (5.60e-4)" "unprognostic (4.02e-3)" "potential prognostic favorable (1.21e-4)" "unprognostic (3.49e-3)" "unprognostic (4.81e-2)" "unprognostic (2.10e-1)" "unprognostic (7.44e-2)" "unprognostic (1.16e-1)" "unprognostic (1.47e-2)" "unprognostic (1.18e-2)" "unprognostic (2.69e-1)" "unprognostic (1.91e-2)" "unprognostic (1.43e-2)" "unprognostic (4.09e-1)" "unprognostic (3.27e-2)" "unprognostic (1.23e-1)" "unprognostic (1.82e-1)" "unprognostic (6.50e-2)" "unprognostic (2.89e-1)" "unprognostic (5.13e-2)" "unprognostic (2.83e-1)" NFAM1 CNAIP ENSG00000235568 "NFAT activating protein with ITAM motif 1" Q8NET5 22 42380407-42432403 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 29.1;lymphoid tissue: 18.8" "Cell type enriched" "Detected in many" 4 "Neutrophils: 560.4" "Group enriched" "Detected in some" 5 "central nervous system macrophage: 38.4;leukocyte: 16.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 90.6" "Group enriched" "Detected in many" 4 "granulocytes: 90.6;monocytes: 48.2" "Cancer enriched" "Detected in single" 10 "Leukemia: 5.4" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Liver - Kupffer cells, Minor Salivary Gland - Macrophages, Pituitary gland - Macrophages, Spleen - Neutrophils_2, Stomach - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA031812 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 7 "Plasma membrane, Cytosol" "HPA031812: " "unprognostic (6.23e-2)" "unprognostic (3.17e-2)" "unprognostic (2.56e-2)" "unprognostic (1.42e-1)" "unprognostic (4.51e-1)" "unprognostic (4.67e-1)" "unprognostic (2.59e-2)" "unprognostic (7.04e-2)" "unprognostic (4.41e-3)" "unprognostic (2.49e-1)" "unprognostic (1.67e-1)" "unprognostic (1.54e-1)" "unprognostic (3.68e-2)" "unprognostic (1.24e-1)" "unprognostic (2.09e-2)" "unprognostic (2.01e-1)" "unprognostic (2.57e-1)" "unprognostic (1.70e-1)" "unprognostic (9.19e-2)" "unprognostic (3.35e-1)" "unprognostic (2.14e-1)" "unprognostic (3.71e-2)" "unprognostic (2.60e-1)" "unprognostic (8.62e-2)" "unprognostic (5.06e-2)" "potential prognostic favorable (2.81e-5)" "unprognostic (2.09e-1)" "unprognostic (3.95e-2)" "unprognostic (6.58e-2)" "unprognostic (3.74e-3)" NFASC "FLJ46866, KIAA0756, NF, NRCAML" ENSG00000163531 Neurofascin O94856 1 204828651-205022822 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.2" "Cell type enhanced" "Detected in many" "Astrocytes: 173.5;Corticotrophs: 231.2;Gonadotrophs: 183.8;Lactotrophs: 202.1;Oligodendrocytes: 575.5;Podocytes: 1255.9;Retinal amacrine cells: 212.7;Retinal bipolar cells: 216.5;Retinal ganglion cells: 173.8;Retinal horizontal cells: 418.7;Rod photoreceptor cells: 321.3;Somatotrophs: 178.4;Thyrotrophs: 179.7;Vascular smooth muscle cells: 205.0" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 899.8" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 18.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 20.2" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Fibroblasts, Breast - Breast myoepithelial cells, Liver - Hepatic stellate cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008832 Enhanced NA NA 270000 "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 11: White matter - Signal transduction" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 57: Podocytes - Glomerular filtration" "HPA008832: " "unprognostic (1.52e-1)" "unprognostic (1.55e-2)" "unprognostic (3.41e-1)" "unprognostic (1.72e-2)" "unprognostic (1.95e-1)" "unprognostic (3.13e-1)" "unprognostic (2.92e-2)" "unprognostic (9.58e-2)" "unprognostic (2.31e-2)" "unprognostic (2.13e-2)" "potential prognostic favorable (3.61e-4)" "unprognostic (3.31e-3)" "unprognostic (6.62e-3)" "unprognostic (8.84e-2)" "potential prognostic favorable (7.16e-6)" "unprognostic (6.14e-2)" "unprognostic (2.37e-1)" "unprognostic (9.51e-2)" "potential prognostic unfavorable (8.68e-4)" "unprognostic (1.19e-1)" "unprognostic (5.59e-2)" "unprognostic (3.25e-3)" "unprognostic (4.69e-1)" "unprognostic (2.26e-1)" "unprognostic (1.91e-1)" "unprognostic (3.92e-2)" "unprognostic (1.77e-1)" "unprognostic (2.54e-2)" "unprognostic (1.62e-1)" "unprognostic (2.01e-1)" NFAT5 "KIAA0827, NF-AT5, NFATL1, NFATZ, OREBP, TONEBP" ENSG00000102908 "Nuclear factor of activated T cells 5" O94916 16 69565094-69704666 "Predicted intracellular proteins, Transcription factors" "DNA damage, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Neutrophils: 1704.9;Renal collecting duct principal cells: 1386.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051528, HPA057304, HPA069711, HPA074040" Approved Enhanced Nucleoplasm,Cytosol Yes No "Cluster 2: Dendritic cells - Unknown function" "Cluster 40: Non-specific - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 12 Nucleoplasm Cytosol "HPA051528: , HPA057304: , HPA069711: , HPA074040: " "unprognostic (7.40e-2)" "unprognostic (7.49e-2)" "unprognostic (8.20e-2)" "unprognostic (3.66e-2)" "unprognostic (3.93e-1)" "unprognostic (1.06e-2)" "unprognostic (1.09e-1)" "unprognostic (3.69e-2)" "unprognostic (1.34e-1)" "validated prognostic favorable (2.82e-7)" "validated prognostic favorable (5.39e-4)" "unprognostic (4.18e-2)" "unprognostic (5.38e-2)" "unprognostic (4.21e-1)" "unprognostic (1.03e-1)" "unprognostic (3.14e-2)" "unprognostic (5.13e-2)" "unprognostic (2.38e-2)" "unprognostic (4.19e-3)" "unprognostic (7.38e-2)" "potential prognostic unfavorable (8.07e-4)" "unprognostic (2.54e-1)" "unprognostic (5.24e-2)" "unprognostic (4.12e-3)" "unprognostic (2.32e-1)" "unprognostic (2.20e-2)" "unprognostic (9.71e-3)" NFATC1 "NF-ATC, NFAT2, NFATc" ENSG00000131196 "Nuclear factor of activated T cells 1" O95644 18 79395856-79529325 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 33.8" "Cell type enhanced" "Detected in many" "B-cells: 124.6;Epididymal basal cells: 141.4;Innate lymphoid cells: 122.1;Lymphatic endothelial cells: 173.9;Salivary basal cells: 129.4;Salivary myoepithelial cells: 287.8" "Cell type enhanced" "Detected in many" "Bergmann glia: 42.8;central nervous system macrophage: 40.7;ependymal cell: 50.1;leukocyte: 46.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "lymphoma: 29.8" "Minor Salivary Gland - Endothelial cells, Spleen - B-cells (Spleen), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004513, HPA071732" Enhanced Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 103: Non-specific - Basic cellular processes" 33 "Nuclear bodies" Nucleoplasm "CAB004513: , HPA071732: " "unprognostic (1.27e-1)" "unprognostic (4.31e-2)" "potential prognostic favorable (4.79e-5)" "unprognostic (1.15e-2)" "unprognostic (6.33e-2)" "unprognostic (3.30e-1)" "unprognostic (8.87e-2)" "unprognostic (1.34e-1)" "unprognostic (4.17e-2)" "unprognostic (9.50e-2)" "unprognostic (2.86e-3)" "unprognostic (3.39e-3)" "unprognostic (6.52e-3)" "unprognostic (1.10e-1)" "unprognostic (1.69e-2)" "unprognostic (9.81e-3)" "unprognostic (2.20e-2)" "unprognostic (6.47e-2)" "unprognostic (5.97e-2)" "unprognostic (8.66e-2)" "unprognostic (1.20e-1)" "unprognostic (2.89e-2)" "unprognostic (1.34e-1)" "unprognostic (2.55e-1)" "unprognostic (1.88e-2)" "potential prognostic favorable (5.38e-5)" "unprognostic (8.71e-2)" "unprognostic (2.71e-1)" "unprognostic (5.46e-2)" "unprognostic (2.37e-3)" "unprognostic (1.68e-1)" NFATC2 "NF-ATP, NFAT1, NFATp" ENSG00000101096 "Nuclear factor of activated T cells 2" Q13469 20 51386957-51562831 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 498.4;Hofbauer cells: 239.6;Mesothelial cells: 243.3;Microglia: 316.3;NK-cells: 321.7;Schwann cells: 756.5" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 409.4;choroid plexus epithelial cell: 316.6;leukocyte: 424.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "skin cancer: 42.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA008789, CAB018567, HPA024369" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 3: Choroid plexus - Cilium" "Cluster 69: Skin cancer - ECM organization" "Cluster 103: Non-specific - Basic cellular processes" 22 "Nucleoplasm, Cytosol" "CAB018567: , HPA008789: , HPA024369: " "unprognostic (2.50e-1)" "unprognostic (2.66e-2)" "unprognostic (2.96e-1)" "unprognostic (2.42e-1)" "unprognostic (1.82e-1)" "unprognostic (3.48e-1)" "unprognostic (2.66e-1)" "unprognostic (1.12e-1)" "unprognostic (5.08e-2)" "unprognostic (7.63e-2)" "unprognostic (1.80e-2)" "unprognostic (2.81e-2)" "unprognostic (5.19e-1)" "unprognostic (6.58e-2)" "unprognostic (8.53e-2)" "unprognostic (1.02e-3)" "unprognostic (1.71e-2)" "unprognostic (5.67e-2)" "unprognostic (1.76e-1)" "unprognostic (9.19e-2)" "unprognostic (2.43e-1)" "unprognostic (7.27e-2)" "unprognostic (1.38e-2)" "unprognostic (1.96e-1)" "unprognostic (5.58e-2)" "unprognostic (7.07e-2)" "unprognostic (8.75e-2)" "unprognostic (2.08e-1)" "unprognostic (8.08e-2)" "unprognostic (2.78e-3)" "unprognostic (4.50e-2)" NFATC2IP "ESC2, FLJ14639, NIP45, RAD60" ENSG00000176953 "Nuclear factor of activated T cells 2 interacting protein" Q8NCF5 16 28950807-28967092 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053587 Approved Nucleoplasm NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 49: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 54: Non-specific - Transcription" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" 2 Nucleoplasm "HPA053587: " "unprognostic (2.61e-1)" "unprognostic (2.55e-1)" "unprognostic (1.62e-1)" "unprognostic (8.05e-2)" "unprognostic (3.47e-2)" "unprognostic (6.17e-2)" "unprognostic (3.61e-1)" "unprognostic (2.11e-3)" "unprognostic (1.58e-2)" "unprognostic (8.58e-3)" "unprognostic (7.91e-2)" "unprognostic (3.01e-2)" "unprognostic (1.87e-1)" "potential prognostic unfavorable (5.12e-4)" "unprognostic (9.75e-2)" "unprognostic (1.09e-1)" "unprognostic (3.99e-2)" "unprognostic (4.56e-2)" "unprognostic (3.79e-3)" "unprognostic (5.20e-2)" "unprognostic (1.45e-1)" "unprognostic (4.92e-2)" "unprognostic (1.52e-2)" "unprognostic (6.62e-3)" "unprognostic (2.99e-2)" "unprognostic (1.06e-1)" "unprognostic (2.66e-2)" "unprognostic (2.39e-1)" "unprognostic (2.60e-2)" "unprognostic (5.18e-2)" "unprognostic (5.30e-2)" NFATC3 "NFAT4, NFATX" ENSG00000072736 "Nuclear factor of activated T cells 3" Q12968 16 68084751-68229259 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 95.0" "Cell type enhanced" "Detected in all" "Myonuclei: 359.8;Podocytes: 353.9" "Cell type enhanced" "Detected in all" "leukocyte: 314.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050665 Supported Nucleoplasm,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 80: Thymus - Adaptive immune response" "Cluster 25: Non-specific - Transcription" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 3 "Nucleoplasm, Cytosol" "HPA050665: " "unprognostic (9.59e-2)" "unprognostic (1.76e-1)" "unprognostic (2.26e-1)" "unprognostic (3.29e-2)" "unprognostic (4.01e-1)" "unprognostic (5.36e-2)" "unprognostic (8.02e-2)" "unprognostic (4.46e-2)" "unprognostic (3.61e-2)" "unprognostic (2.11e-2)" "potential prognostic favorable (2.29e-4)" "unprognostic (1.37e-3)" "unprognostic (8.61e-2)" "unprognostic (5.41e-2)" "unprognostic (2.94e-2)" "unprognostic (1.30e-2)" "unprognostic (3.75e-1)" "unprognostic (1.29e-1)" "unprognostic (7.68e-3)" "unprognostic (1.55e-1)" "unprognostic (3.65e-3)" "unprognostic (1.53e-1)" "unprognostic (3.49e-1)" "unprognostic (9.75e-2)" "unprognostic (2.81e-2)" "unprognostic (1.49e-1)" "unprognostic (1.63e-2)" "unprognostic (1.35e-1)" "unprognostic (3.94e-1)" "unprognostic (1.48e-2)" "unprognostic (2.01e-3)" NFATC4 NFAT3 ENSG00000100968 "Nuclear factor of activated T cells 4" Q14934 14 24365673-24379604 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Astrocytes: 54.4;Bergmann glia: 39.5" "Group enriched" "Detected in many" 6 "astrocyte: 51.7;Bergmann glia: 42.6;fibroblast: 64.9;pericyte: 76.1;vascular associated smooth muscle cell: 47.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 23.4" "Adipose visceral - Adipose progenitor cells, Prostate - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA031641, CAB032859, HPA076526" Uncertain Supported "Nuclear speckles,Cytosol" No No "Cluster 75: Ovary - Mixed function" "Cluster 44: Non-specific - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 22: Non-specific - Basic cellular functions" 4 "Nuclear speckles, Cytosol" "CAB032859: , HPA031641: , HPA076526: " "unprognostic (9.21e-3)" "unprognostic (2.35e-1)" "unprognostic (1.57e-1)" "unprognostic (3.11e-2)" "unprognostic (9.22e-2)" "unprognostic (1.82e-1)" "unprognostic (1.24e-1)" "unprognostic (6.08e-2)" "unprognostic (6.13e-2)" "unprognostic (1.05e-2)" "unprognostic (6.68e-2)" "unprognostic (1.44e-2)" "unprognostic (7.46e-2)" "unprognostic (1.28e-1)" "unprognostic (2.17e-2)" "unprognostic (4.24e-2)" "unprognostic (4.61e-3)" "unprognostic (1.12e-1)" "unprognostic (1.24e-1)" "unprognostic (6.75e-2)" "unprognostic (4.42e-2)" "unprognostic (1.45e-1)" "unprognostic (4.24e-2)" "unprognostic (2.83e-2)" "unprognostic (4.95e-3)" "unprognostic (3.69e-1)" "unprognostic (2.21e-1)" "unprognostic (2.97e-2)" "unprognostic (1.07e-1)" "unprognostic (4.62e-2)" "unprognostic (1.49e-1)" NFE2 NF-E2 ENSG00000123405 "Nuclear factor, erythroid 2" Q16621 12 54292111-54301015 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 106.1;lymphoid tissue: 45.9" "Cell type enhanced" "Detected in some" "Erythrocyte progenitors: 76.4;Erythrocytes: 97.5;Megakaryocyte progenitors: 70.8;Megakaryocyte-Erythroid progenitors: 78.3;Megakaryocytes: 210.2;Monocyte progenitors: 84.2;Neutrophil progenitors: 80.8;Neutrophils: 300.7;Platelets: 651.5" "Group enriched" "Detected in some" 9 "choroid plexus epithelial cell: 2.6;leukocyte: 2.8" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 8.5" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 5 "basophil: 1493.0;neutrophil: 813.5" "Lineage enriched" "Detected in many" 6 "granulocytes: 1493.0" "Cancer enriched" "Detected in many" 7 "Leukemia: 95.2" "Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophils_2, Skin - Keratinocyte (granular), Spleen - Neutrophils_2, Stomach - Neutrophils, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA001914 Enhanced Approved "Nucleoplasm,Actin filaments" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 47: Leukemia - Hemostasis" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 10 "Nucleoplasm, Actin filaments" "HPA001914: " "unprognostic (3.34e-2)" "unprognostic (4.16e-3)" "unprognostic (8.38e-2)" "unprognostic (3.00e-2)" "unprognostic (6.63e-2)" "unprognostic (1.01e-1)" "unprognostic (1.22e-1)" "unprognostic (8.32e-3)" "unprognostic (1.49e-1)" "unprognostic (1.68e-2)" "unprognostic (2.11e-1)" "unprognostic (1.12e-1)" "unprognostic (7.90e-2)" "unprognostic (1.81e-2)" "unprognostic (2.65e-3)" "unprognostic (1.28e-2)" "unprognostic (1.79e-1)" "unprognostic (5.62e-3)" "unprognostic (1.10e-1)" "unprognostic (3.31e-3)" "unprognostic (1.16e-1)" NFE2L1 "FLJ00380, LCR-F1, NRF-1, NRF1, TCF11" ENSG00000082641 "NFE2 like bZIP transcription factor 1" Q14494 17 48048329-48061545 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 1273.4;tongue: 800.7" "Cell type enhanced" "Detected in many" "Thymic myoid cells: 353.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Spleen - Endothelial cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063384, HPA065424" Approved Approved Nucleoplasm,Cytosol "Intracellular and membrane" Transcription NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 44: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 17 Nucleoplasm Cytosol "HPA063384: , HPA065424: " "unprognostic (2.21e-2)" "unprognostic (2.01e-1)" "unprognostic (2.36e-1)" "unprognostic (2.46e-3)" "unprognostic (2.38e-1)" "unprognostic (4.40e-3)" "unprognostic (1.41e-1)" "unprognostic (2.55e-3)" "unprognostic (3.64e-3)" "unprognostic (6.89e-2)" "potential prognostic favorable (1.42e-5)" "unprognostic (8.61e-3)" "unprognostic (6.85e-3)" "unprognostic (8.45e-2)" "unprognostic (1.26e-1)" "unprognostic (1.49e-1)" "unprognostic (6.07e-2)" "unprognostic (2.64e-1)" "unprognostic (5.18e-2)" "unprognostic (1.91e-2)" "unprognostic (8.03e-2)" "unprognostic (5.52e-2)" "unprognostic (4.43e-2)" "unprognostic (1.33e-1)" "unprognostic (1.80e-1)" "unprognostic (1.48e-2)" "unprognostic (2.34e-1)" "unprognostic (2.87e-1)" "unprognostic (2.95e-1)" "unprognostic (7.04e-3)" "unprognostic (2.21e-2)" NFE2L2 "NRF-2, NRF2" ENSG00000116044 "NFE2 like bZIP transcription factor 2" Q16236 2 177218667-177392756 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 2257.6;Renal connecting tubule cells: 1877.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002990, CAB020317, HPA043438" Supported Approved "Nucleoplasm,Golgi apparatus,Plasma membrane,Centrosome,Basal body,Cytosol" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 153 "Nucleoplasm, Plasma membrane" "Golgi apparatus, Centrosome, Basal body, Cytosol" "CAB020317: , HPA002990: , HPA043438: " "unprognostic (1.27e-2)" "unprognostic (6.53e-2)" "unprognostic (3.58e-2)" "unprognostic (1.19e-1)" "unprognostic (1.76e-1)" "unprognostic (6.20e-3)" "unprognostic (1.88e-1)" "unprognostic (7.39e-3)" "unprognostic (1.59e-1)" "unprognostic (3.16e-1)" "potential prognostic favorable (1.05e-5)" "unprognostic (2.45e-3)" "unprognostic (1.30e-1)" "unprognostic (1.25e-2)" "unprognostic (3.53e-1)" "unprognostic (2.45e-1)" "unprognostic (2.89e-2)" "unprognostic (5.11e-2)" "unprognostic (1.13e-2)" "unprognostic (1.91e-1)" "unprognostic (5.42e-2)" "unprognostic (8.50e-3)" "unprognostic (7.58e-2)" "unprognostic (2.65e-1)" "unprognostic (1.86e-1)" "unprognostic (4.55e-2)" "unprognostic (4.04e-2)" "unprognostic (3.12e-2)" "unprognostic (2.22e-1)" "unprognostic (7.04e-2)" "unprognostic (1.56e-1)" NFE2L3 Nrf3 ENSG00000050344 "NFE2 like bZIP transcription factor 3" Q9Y4A8 7 26152198-26187137 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 32.3" "Cell type enhanced" "Detected in many" "Breast secretory cells: 236.4;Cytotrophoblasts: 470.6;Epicardial cells: 1050.7;Paneth cells: 293.9;Syncytiotrophoblasts: 940.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA055889 Enhanced Approved Nucleoplasm,Vesicles "Intracellular and membrane" Transcription NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 35: Non-specific - DNA binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 20: Non-specific - Transcription regulation" 10 "Nucleoplasm, Vesicles" "HPA055889: " "unprognostic (2.35e-1)" "unprognostic (3.30e-1)" "unprognostic (6.04e-3)" "unprognostic (5.45e-2)" "unprognostic (5.67e-2)" "unprognostic (8.31e-2)" "unprognostic (1.20e-1)" "potential prognostic unfavorable (1.38e-5)" "unprognostic (1.09e-1)" "unprognostic (5.19e-2)" "unprognostic (6.09e-3)" "unprognostic (1.83e-3)" "unprognostic (3.74e-2)" "unprognostic (1.85e-3)" "unprognostic (9.52e-3)" "unprognostic (4.18e-2)" "unprognostic (2.61e-1)" "unprognostic (2.30e-1)" "unprognostic (1.70e-1)" "unprognostic (1.86e-1)" "unprognostic (1.39e-1)" "potential prognostic unfavorable (4.36e-4)" "unprognostic (2.17e-2)" "unprognostic (6.65e-2)" "potential prognostic favorable (9.10e-4)" "unprognostic (5.40e-2)" "unprognostic (1.23e-1)" "unprognostic (3.11e-3)" "unprognostic (1.23e-1)" "unprognostic (2.08e-1)" "unprognostic (9.05e-2)" NFIA "KIAA1439, NFI-L" ENSG00000162599 "Nuclear factor I A" Q12857 1 60865259-61462788 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "DNA replication, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 1727.8;Bergmann glia: 1757.6;Choroid plexus epithelial cells: 2101.8;Pituitary stem cells: 2323.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Liver - Hepatocytes, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006111, HPA008884" Enhanced Enhanced Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 25: Non-specific - Transcription" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 151 Nucleoplasm "HPA006111: , HPA008884: " "unprognostic (7.59e-2)" "unprognostic (3.84e-2)" "unprognostic (1.32e-1)" "unprognostic (1.66e-2)" "unprognostic (3.30e-3)" "unprognostic (3.21e-1)" "unprognostic (3.64e-2)" "unprognostic (1.07e-1)" "unprognostic (3.59e-2)" "unprognostic (1.93e-3)" "validated prognostic favorable (6.36e-8)" "validated prognostic favorable (1.11e-6)" "unprognostic (1.05e-2)" "unprognostic (3.74e-2)" "unprognostic (6.17e-3)" "unprognostic (6.83e-2)" "unprognostic (2.80e-1)" "unprognostic (7.18e-2)" "unprognostic (9.13e-2)" "unprognostic (9.67e-2)" "unprognostic (5.03e-3)" "unprognostic (2.58e-3)" "unprognostic (7.43e-2)" "unprognostic (6.60e-2)" "unprognostic (1.17e-1)" "unprognostic (1.06e-1)" "unprognostic (4.18e-2)" "unprognostic (2.43e-1)" "unprognostic (2.69e-1)" "unprognostic (6.58e-3)" "unprognostic (4.55e-2)" NFIB "NFI-RED, NFIB2, NFIB3" ENSG00000147862 "Nuclear factor I B" O00712 9 14081843-14398983 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "DNA replication, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Prostatic glandular cells: 1230.7;Salivary acinar cells: 1181.3;Salivary myoepithelial cells: 1651.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003956 Supported Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 34: Non-specific - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 121 "Nucleoplasm, Nucleoli fibrillar center" "HPA003956: " "unprognostic (3.66e-2)" "unprognostic (1.80e-1)" "unprognostic (1.75e-1)" "unprognostic (1.58e-1)" "unprognostic (2.21e-1)" "unprognostic (6.43e-2)" "unprognostic (1.97e-1)" "unprognostic (1.37e-1)" "unprognostic (2.91e-2)" "unprognostic (1.45e-1)" "validated prognostic favorable (2.90e-7)" "validated prognostic favorable (7.44e-5)" "unprognostic (4.02e-3)" "unprognostic (7.48e-2)" "unprognostic (3.25e-3)" "unprognostic (1.32e-2)" "unprognostic (6.91e-2)" "unprognostic (4.40e-2)" "unprognostic (1.37e-2)" "unprognostic (3.11e-1)" "unprognostic (2.24e-1)" "unprognostic (2.38e-1)" "unprognostic (2.14e-1)" "unprognostic (1.98e-1)" "unprognostic (2.18e-1)" "unprognostic (3.92e-2)" "unprognostic (5.10e-3)" "unprognostic (4.05e-1)" "unprognostic (1.21e-1)" "unprognostic (8.80e-3)" "unprognostic (2.08e-1)" NFIC "CTF, CTF5, NF-I, NFI" ENSG00000141905 "Nuclear factor I C" P08651 19 3314403-3469217 "Predicted intracellular proteins, Transcription factors" "DNA replication, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 255.9" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004300, CAB004674, HPA052625, HPA063560" Supported Enhanced "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 18: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 108: Fibroblasts - ECM organization" 136 "Nucleoplasm, Nucleoli fibrillar center" "CAB004300: , CAB004674: , HPA052625: , HPA063560: " "unprognostic (1.84e-3)" "unprognostic (6.26e-2)" "unprognostic (1.48e-2)" "unprognostic (2.24e-1)" "unprognostic (2.11e-1)" "unprognostic (1.44e-2)" "unprognostic (1.05e-1)" "unprognostic (7.35e-2)" "unprognostic (1.27e-2)" "unprognostic (7.84e-2)" "potential prognostic favorable (7.79e-5)" "unprognostic (1.45e-1)" "unprognostic (4.91e-3)" "unprognostic (1.09e-1)" "unprognostic (9.80e-2)" "unprognostic (8.72e-2)" "unprognostic (3.73e-2)" "unprognostic (1.52e-1)" "unprognostic (9.21e-2)" "unprognostic (3.05e-2)" "unprognostic (3.33e-1)" "unprognostic (7.46e-2)" "unprognostic (2.77e-1)" "unprognostic (1.83e-1)" "unprognostic (1.37e-1)" "unprognostic (4.08e-2)" "unprognostic (2.16e-1)" "unprognostic (1.22e-2)" "unprognostic (1.84e-1)" "unprognostic (4.90e-3)" "unprognostic (3.74e-2)" NFIL3 "E4BP4, IL3BP1, NF-IL3A, NFIL3A" ENSG00000165030 "Nuclear factor, interleukin 3 regulated" Q16649 9 91409045-91423832 "Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial luminal cells: 231.4;monocytes: 320.4;Neutrophils: 1247.3;Smooth muscle cells: 285.7;Vascular smooth muscle cells: 255.2" "Cell type enhanced" "Detected in many" "vascular associated smooth muscle cell: 68.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 58.0;neutrophil: 27.0" "Lineage enriched" "Detected in many" 35 "granulocytes: 58.0" "Low cancer specificity" "Detected in all" "Colon - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003261 Approved Approved "Nuclear bodies" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 13 "Nuclear bodies" "HPA003261: " "unprognostic (3.08e-1)" "unprognostic (8.46e-2)" "unprognostic (5.35e-2)" "unprognostic (9.84e-2)" "unprognostic (2.87e-1)" "unprognostic (4.68e-2)" "unprognostic (1.68e-1)" "unprognostic (1.53e-1)" "unprognostic (1.18e-2)" "unprognostic (1.70e-1)" "unprognostic (1.73e-2)" "unprognostic (1.68e-1)" "unprognostic (4.16e-2)" "unprognostic (1.07e-1)" "unprognostic (1.75e-2)" "unprognostic (2.47e-2)" "unprognostic (2.11e-2)" "unprognostic (1.88e-1)" "unprognostic (2.88e-1)" "unprognostic (2.17e-3)" "unprognostic (2.54e-1)" "unprognostic (1.28e-1)" "unprognostic (2.23e-3)" "unprognostic (2.11e-1)" "unprognostic (7.04e-2)" "unprognostic (2.08e-3)" "unprognostic (9.95e-2)" "unprognostic (1.27e-2)" "unprognostic (1.63e-1)" "unprognostic (8.95e-3)" "unprognostic (2.29e-1)" NFILZ LINC01862 ENSG00000268480 "NFIL3 like basic leucine zipper" A0A5F9ZHS7 19 8630633-8681151 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in single" "testis: 1.5" "Group enriched" "Detected in some" 27 "Early spermatids: 86.1;Late spermatids: 329.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 20 "NK-cell: 14.5" "Lineage enriched" "Detected in single" 20 "NK-cells: 14.5" "Low cancer specificity" "Detected in some" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 40: Non-specific - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 54: Non-specific - Transcription" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" NFIX NF1A ENSG00000008441 "Nuclear factor I X" Q14938 19 12995475-13098796 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "DNA replication, Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 391.4" "Cell type enhanced" "Detected in many" "Pituitary stem cells: 336.1;Prostatic glandular cells: 322.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 157.9" "Kidney - Fibroblasts, Pituitary gland - Undifferentiated cells (Pituitary gland), Skeletal muscle - Skeletal myocytes, Spleen - Fibroblasts_1, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007533 Supported Supported Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 108: Fibroblasts - ECM organization" 159 Nucleoplasm "HPA007533: " "unprognostic (2.25e-3)" "unprognostic (2.37e-1)" "unprognostic (3.14e-2)" "unprognostic (1.75e-1)" "unprognostic (2.54e-1)" "unprognostic (4.64e-3)" "unprognostic (2.18e-1)" "unprognostic (2.80e-1)" "unprognostic (6.35e-2)" "unprognostic (6.22e-3)" "potential prognostic favorable (7.39e-6)" "unprognostic (5.24e-3)" "unprognostic (2.01e-1)" "potential prognostic favorable (6.15e-4)" "unprognostic (1.73e-2)" "unprognostic (3.63e-3)" "unprognostic (2.61e-1)" "unprognostic (1.48e-1)" "unprognostic (8.01e-2)" "unprognostic (3.67e-3)" "unprognostic (8.07e-2)" "unprognostic (2.67e-2)" "unprognostic (4.01e-3)" "unprognostic (3.48e-1)" "unprognostic (1.23e-2)" "unprognostic (5.04e-3)" "unprognostic (2.03e-1)" "unprognostic (9.63e-2)" "unprognostic (2.70e-2)" "unprognostic (1.23e-2)" "unprognostic (1.56e-1)" NFKB1 "KBF1, NF-kappaB, NF-kB1, NFkappaB, NFKB-p50, p105, p50" ENSG00000109320 "Nuclear factor kappa B subunit 1" P19838 4 102501330-102617302 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins, Transcription factors" "Apoptosis, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "cDC: 1331.0;Endometrial glandular cells: 1553.6;Endometrial luminal cells: 1403.3;Epicardial cells: 1148.4;Innate lymphoid cells: 1999.1;Macrophages: 1132.5;Mast cells: 2181.6;monocytes: 2370.6;Neutrophils: 3104.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004031, HPA027305" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 61: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 124 Nucleoplasm Cytosol "CAB004031: , HPA027305: " "unprognostic (4.37e-2)" "unprognostic (2.31e-1)" "unprognostic (7.65e-2)" "unprognostic (2.82e-3)" "unprognostic (5.42e-2)" "unprognostic (3.43e-1)" "unprognostic (2.03e-1)" "unprognostic (2.74e-1)" "unprognostic (5.06e-2)" "unprognostic (3.08e-3)" "validated prognostic favorable (4.25e-8)" "validated prognostic favorable (2.69e-5)" "unprognostic (3.00e-2)" "unprognostic (2.33e-1)" "unprognostic (2.50e-1)" "unprognostic (2.70e-1)" "potential prognostic unfavorable (5.09e-4)" "unprognostic (4.18e-3)" "unprognostic (3.47e-2)" "unprognostic (2.31e-2)" "unprognostic (1.50e-1)" "unprognostic (7.62e-2)" "unprognostic (2.20e-2)" "unprognostic (1.36e-1)" "potential prognostic favorable (3.66e-4)" "unprognostic (9.03e-2)" "unprognostic (4.05e-1)" "unprognostic (2.80e-1)" "unprognostic (5.26e-3)" "unprognostic (1.07e-2)" "unprognostic (4.41e-1)" NFKB2 "LYT-10, NF-kB2, p105, p49/p100, p52" ENSG00000077150 "Nuclear factor kappa B subunit 2" Q00653 10 102394110-102402524 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Mast cells: 93.3;monocytes: 80.6;Neutrophils: 258.6;Oocytes: 101.3;Pancreatic duct cells: 84.1" "Cell type enhanced" "Detected in some" "endothelial cell: 13.5;leukocyte: 9.8;vascular associated smooth muscle cell: 10.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.9" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 129.7" "Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008422, CAB022098, HPA023900" Enhanced Enhanced Nucleoplasm,Cytosol NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 55: Lymphoma - Immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 43 "Nucleoplasm, Cytosol" "CAB022098: , HPA008422: , HPA023900: " "unprognostic (9.83e-2)" "unprognostic (9.75e-3)" "unprognostic (2.18e-3)" "unprognostic (1.66e-1)" "unprognostic (1.66e-2)" "unprognostic (8.13e-2)" "unprognostic (3.23e-3)" "unprognostic (6.83e-2)" "unprognostic (1.38e-1)" "unprognostic (9.92e-3)" "potential prognostic unfavorable (5.50e-4)" "unprognostic (2.31e-2)" "unprognostic (3.48e-3)" "unprognostic (1.02e-3)" "unprognostic (1.59e-1)" "unprognostic (9.04e-3)" "unprognostic (2.77e-2)" "unprognostic (3.19e-2)" "unprognostic (3.17e-1)" "unprognostic (2.20e-1)" "unprognostic (2.18e-1)" "unprognostic (2.12e-1)" "unprognostic (1.07e-3)" "unprognostic (4.38e-3)" "unprognostic (9.50e-2)" "potential prognostic favorable (3.88e-4)" "potential prognostic favorable (1.19e-4)" "unprognostic (3.84e-2)" "unprognostic (1.90e-1)" "unprognostic (2.20e-1)" "unprognostic (1.09e-2)" NFKBIA "IkappaBalpha, IKBA, MAD-3, NFKBI" ENSG00000100906 "NFKB inhibitor alpha" P25963 14 35401079-35404749 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Host-virus interaction" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 960.5" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 2777.8;cDC: 2053.9;Epididymal basal cells: 3421.2;Esophageal apical cells: 2243.2;Mast cells: 2588.5;monocytes: 2713.6;Neutrophils: 7958.7;Suprabasal keratinocytes: 2317.9" "Cell type enriched" "Detected in all" 4 "endothelial cell: 393.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003815, HPA029207" Approved Enhanced Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 15: Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 55: Lymphoma - Immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 107 Cytosol "CAB003815: , HPA029207: " "unprognostic (2.96e-2)" "potential prognostic favorable (5.58e-4)" "unprognostic (9.12e-2)" "unprognostic (2.35e-1)" "unprognostic (6.18e-2)" "unprognostic (2.55e-1)" "unprognostic (2.00e-1)" "unprognostic (2.87e-1)" "unprognostic (1.07e-1)" "unprognostic (3.28e-1)" "potential prognostic favorable (2.14e-5)" "unprognostic (4.74e-2)" "unprognostic (4.71e-1)" "unprognostic (1.19e-1)" "unprognostic (4.91e-2)" "unprognostic (5.53e-2)" "unprognostic (2.08e-2)" "unprognostic (4.68e-1)" "unprognostic (2.45e-1)" "unprognostic (5.02e-2)" "potential prognostic favorable (2.80e-4)" "unprognostic (3.18e-2)" "potential prognostic unfavorable (6.31e-4)" "unprognostic (1.27e-1)" "unprognostic (1.48e-1)" "unprognostic (1.45e-2)" "unprognostic (2.98e-1)" "unprognostic (1.64e-1)" "unprognostic (1.22e-2)" "unprognostic (4.63e-2)" "unprognostic (2.63e-1)" NFKBIB "IKBB, TRIP9" ENSG00000104825 "NFKB inhibitor beta" Q15653 19 38899700-38908893 "Predicted intracellular proteins, Transcription factors" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 72.2" "Group enriched" "Detected in many" 29 "Early spermatids: 896.1;Late spermatids: 1279.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063734 Approved Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 67: Testis - Mixed function" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 62 Nucleoplasm Cytosol "HPA063734: " "unprognostic (4.92e-3)" "unprognostic (4.02e-2)" "unprognostic (4.46e-2)" "potential prognostic unfavorable (6.68e-4)" "unprognostic (8.93e-2)" "unprognostic (2.45e-1)" "unprognostic (1.85e-1)" "unprognostic (1.08e-1)" "unprognostic (2.24e-1)" "unprognostic (9.06e-2)" "unprognostic (1.24e-3)" "unprognostic (1.37e-1)" "unprognostic (1.08e-1)" "unprognostic (7.71e-2)" "unprognostic (4.61e-2)" "unprognostic (3.84e-2)" "unprognostic (3.75e-1)" "unprognostic (5.88e-2)" "unprognostic (1.46e-1)" "unprognostic (1.12e-2)" "unprognostic (3.67e-1)" "unprognostic (2.72e-2)" "unprognostic (1.42e-1)" "unprognostic (2.23e-2)" "unprognostic (1.39e-1)" "unprognostic (3.31e-1)" "unprognostic (1.02e-1)" "unprognostic (2.22e-1)" "unprognostic (2.92e-1)" "unprognostic (5.87e-3)" "unprognostic (1.22e-1)" NFKBID "IkappaBNS, IkBNS, TA-NFKBH" ENSG00000167604 "NFKB inhibitor delta" Q8NI38 19 35887653-35902303 "Predicted intracellular proteins, Transcription factors" "Inflammatory response" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.4" "Cell type enhanced" "Detected in many" "B-cells: 125.4;cDC: 287.1;Endometrial luminal cells: 112.1;Fallopian secretory cells: 116.7;Hofbauer cells: 115.5;Innate lymphoid cells: 134.0;Macrophages: 134.1;Mast cells: 203.5;monocytes: 191.8;Neutrophil progenitors: 154.6;Neutrophils: 490.1;pDCs: 147.7" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 34.3;leukocyte: 30.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "lymphoma: 16.6" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA054778 Approved "Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 15: Bone marrow - Innate immune response" "Cluster 25: Non-specific - Transcription" "Cluster 55: Lymphoma - Immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 83 Cytosol "Nuclear bodies, Plasma membrane" "HPA054778: " "unprognostic (1.66e-2)" "unprognostic (2.53e-2)" "unprognostic (1.64e-2)" "unprognostic (5.08e-2)" "unprognostic (2.35e-1)" "unprognostic (3.38e-2)" "unprognostic (1.57e-2)" "unprognostic (1.31e-1)" "potential prognostic favorable (2.00e-4)" "unprognostic (2.54e-1)" "unprognostic (8.94e-2)" "unprognostic (1.18e-2)" "unprognostic (1.10e-1)" "unprognostic (3.70e-2)" "unprognostic (1.39e-1)" "unprognostic (2.20e-2)" "unprognostic (2.04e-2)" "unprognostic (1.41e-2)" "unprognostic (2.50e-2)" "unprognostic (1.89e-2)" "unprognostic (3.91e-3)" "unprognostic (1.12e-1)" "potential prognostic favorable (7.81e-5)" "unprognostic (9.11e-2)" "unprognostic (5.09e-2)" "unprognostic (3.64e-2)" NFKBIE IKBE ENSG00000146232 "NFKB inhibitor epsilon" O00221 6 44258166-44265788 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 33.5" "Cell type enhanced" "Detected in many" "cDC: 74.3;Epididymal basal cells: 44.2;Epididymal clear cells: 77.6;Epididymal efferent duct absorptive cells: 46.0;Hofbauer cells: 62.5;Late spermatids: 59.4;monocytes: 48.8;Neutrophils: 52.7;Pancreatic duct cells: 50.7" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 7.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002692, HPA005941, CAB010272" Supported Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 25: Non-specific - Transcription" "Cluster 55: Lymphoma - Immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 20 "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "CAB010272: , HPA002692: , HPA005941: " "unprognostic (1.18e-1)" "potential prognostic favorable (1.58e-4)" "unprognostic (4.82e-2)" "unprognostic (3.09e-1)" "unprognostic (1.03e-1)" "unprognostic (4.09e-2)" "potential prognostic unfavorable (5.84e-4)" "unprognostic (4.40e-2)" "unprognostic (2.38e-1)" "unprognostic (1.06e-1)" "unprognostic (4.10e-3)" "unprognostic (2.99e-2)" "unprognostic (3.91e-2)" "potential prognostic unfavorable (2.62e-4)" "unprognostic (7.75e-3)" "unprognostic (1.89e-2)" "unprognostic (7.89e-3)" "unprognostic (9.01e-2)" "unprognostic (1.03e-1)" "unprognostic (9.12e-2)" "unprognostic (1.73e-1)" "unprognostic (8.56e-2)" "unprognostic (5.30e-2)" "unprognostic (2.85e-1)" "unprognostic (1.01e-1)" "unprognostic (6.98e-2)" "unprognostic (3.08e-1)" "unprognostic (7.31e-2)" "unprognostic (3.77e-2)" "unprognostic (4.27e-2)" "unprognostic (2.59e-2)" NFKBIL1 "IKBL, NFKBIL" ENSG00000204498 "NFKB inhibitor like 1" Q9UBC1 6 31546870-31558829 "Human disease related genes, Predicted intracellular proteins, Transcription factors" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 12.0;Bergmann glia: 16.2;Brain excitatory neurons: 9.6;Brain inhibitory neurons: 9.0;Choroid plexus epithelial cells: 6.3;Distal convoluted tubule cells: 9.4;Ependymal cells: 8.4;Loop of henle epithelial cells: 8.3;Microglia: 7.7;Oligodendrocyte progenitor cells: 9.3;Oligodendrocytes: 10.7;Other brain neurons: 10.8;Papillary tip epithelial cells: 6.6;Podocytes: 6.7;Proximal tubule cells: 8.6;Renal collecting duct intercalated cells: 6.7;Renal collecting duct principal cells: 8.3;Renal connecting tubule cells: 6.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "thyroid cancer: 4.6" "Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006298 Supported Nucleoplasm NA NA "Cluster 64: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 98: Neurons - Neurotransmission & signaling" 8 Nucleoplasm "HPA006298: " "unprognostic (4.46e-2)" "unprognostic (6.27e-1)" "unprognostic (2.17e-1)" "unprognostic (4.82e-2)" "unprognostic (5.03e-1)" "unprognostic (8.03e-2)" "unprognostic (2.03e-1)" "unprognostic (5.32e-1)" "unprognostic (4.67e-1)" "potential prognostic unfavorable (2.56e-4)" "unprognostic (8.21e-1)" "unprognostic (2.67e-1)" "unprognostic (1.68e-1)" "unprognostic (6.54e-1)" "unprognostic (3.09e-1)" "unprognostic (2.08e-1)" NFKBIZ "FLJ34463, INAP, MAIL" ENSG00000144802 "NFKB inhibitor zeta" Q9BYH8 3 101827991-101861022 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "bone marrow: 383.6" "Cell type enriched" "Detected in many" 4 "Neutrophils: 3464.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 34.1" "Group enriched" "Detected in many" 5 "granulocytes: 24.8;monocytes: 34.1" "Cancer enhanced" "Detected in all" "Kidney cancer: 90.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA010547, HPA075363" Enhanced Supported "Nuclear speckles,Cytoplasmic bodies" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 15: Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 55: Lymphoma - Immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 2 "Nuclear speckles" "Cytoplasmic bodies" "HPA010547: , HPA075363: " "unprognostic (6.15e-2)" "unprognostic (9.44e-3)" "unprognostic (1.19e-1)" "potential prognostic unfavorable (2.30e-4)" "unprognostic (2.64e-2)" "unprognostic (2.01e-1)" "unprognostic (2.27e-3)" "unprognostic (7.44e-2)" "unprognostic (5.15e-3)" "unprognostic (8.30e-2)" "potential prognostic unfavorable (3.74e-7)" "unprognostic (2.04e-1)" "unprognostic (1.88e-1)" "unprognostic (8.11e-3)" "unprognostic (2.42e-3)" "unprognostic (9.31e-3)" "unprognostic (3.52e-2)" "unprognostic (7.83e-2)" "unprognostic (1.56e-1)" "unprognostic (5.08e-2)" "unprognostic (6.06e-2)" "unprognostic (1.97e-1)" "unprognostic (3.13e-2)" "unprognostic (2.04e-1)" "unprognostic (8.79e-3)" "unprognostic (7.98e-2)" "unprognostic (1.89e-1)" "unprognostic (1.22e-1)" "unprognostic (8.04e-2)" "unprognostic (2.38e-1)" "unprognostic (2.63e-1)" NFRKB "DKFZp547B2013, INO80G" ENSG00000170322 "Nuclear factor related to kappaB binding protein" Q6P4R8 11 129863636-129895590 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 85.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007082, HPA007128" Approved Enhanced Nucleoplasm Yes No "Cluster 42: Non-specific - Vesicular transport" "Cluster 39: Testis - Nuclear processes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 24: Non-specific - Unknown function" "Cluster 26: Keratinocytes - Keratinization" 32 Nucleoplasm "HPA007082: , HPA007128: " "unprognostic (4.57e-3)" "unprognostic (2.38e-2)" "potential prognostic favorable (1.81e-4)" "unprognostic (1.07e-1)" "unprognostic (1.63e-1)" "unprognostic (1.76e-2)" "unprognostic (5.23e-2)" "potential prognostic favorable (1.16e-4)" "unprognostic (9.21e-2)" "unprognostic (3.91e-2)" "unprognostic (2.08e-3)" "unprognostic (4.88e-3)" "unprognostic (2.36e-1)" "unprognostic (1.20e-3)" "unprognostic (1.99e-1)" "unprognostic (4.21e-1)" "unprognostic (5.44e-3)" "unprognostic (8.23e-2)" "unprognostic (9.17e-2)" "unprognostic (2.33e-1)" "unprognostic (2.10e-1)" "unprognostic (1.61e-1)" "unprognostic (7.47e-3)" "unprognostic (7.91e-2)" "potential prognostic favorable (4.64e-4)" "unprognostic (9.11e-2)" "unprognostic (2.18e-3)" "unprognostic (1.08e-1)" "unprognostic (2.57e-1)" "unprognostic (3.57e-1)" "unprognostic (7.76e-2)" NFS1 "IscS, NifS" ENSG00000244005 "NFS1 cysteine desulfurase" Q9Y697 20 35668052-35699355 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Molybdenum cofactor biosynthesis" Transferase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 20.4;Cardiomyocytes: 19.0;Myonuclei: 24.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034314, HPA051801, HPA054755" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 76: Non-specific - Metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 11 "Nucleoplasm, Cytosol" "CAB034314: , HPA051801: , HPA054755: " "unprognostic (3.49e-2)" "unprognostic (5.09e-2)" "unprognostic (3.60e-1)" "unprognostic (5.33e-2)" "unprognostic (5.37e-2)" "unprognostic (2.39e-2)" "unprognostic (2.14e-1)" "unprognostic (1.70e-1)" "unprognostic (5.92e-2)" "unprognostic (5.77e-3)" "potential prognostic favorable (3.16e-7)" "unprognostic (2.75e-2)" "unprognostic (3.31e-1)" "unprognostic (3.18e-2)" "unprognostic (9.52e-3)" "unprognostic (1.65e-2)" "unprognostic (1.88e-1)" "unprognostic (1.40e-1)" "unprognostic (6.40e-2)" "unprognostic (9.01e-2)" "unprognostic (7.43e-2)" "unprognostic (1.37e-1)" "unprognostic (2.43e-2)" "unprognostic (9.93e-2)" "unprognostic (2.79e-2)" "unprognostic (1.73e-1)" "unprognostic (1.52e-1)" "unprognostic (1.81e-2)" "unprognostic (2.12e-2)" "unprognostic (2.40e-3)" "unprognostic (1.99e-1)" NFU1 "CGI-33, HIRIP5, NifU, NIFUC" ENSG00000169599 "NFU1 iron-sulfur cluster scaffold" Q9UMS0 2 69396113-69437628 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 189.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035826 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 19 Cytosol Nucleoplasm "HPA035826: " "unprognostic (3.04e-1)" "unprognostic (2.11e-1)" "unprognostic (3.32e-1)" "unprognostic (1.24e-2)" "unprognostic (1.17e-1)" "unprognostic (1.56e-2)" "unprognostic (1.80e-1)" "unprognostic (2.20e-1)" "unprognostic (4.05e-3)" "unprognostic (7.53e-3)" "potential prognostic favorable (1.05e-10)" "unprognostic (2.03e-2)" "unprognostic (7.93e-3)" "unprognostic (9.23e-3)" "potential prognostic unfavorable (1.76e-5)" "unprognostic (2.09e-3)" "unprognostic (1.80e-1)" "unprognostic (1.29e-2)" "unprognostic (1.55e-1)" "unprognostic (1.14e-1)" "unprognostic (1.77e-1)" "unprognostic (3.21e-2)" "unprognostic (8.29e-2)" "unprognostic (6.46e-2)" "unprognostic (1.19e-1)" "unprognostic (1.30e-1)" "unprognostic (1.19e-2)" "unprognostic (1.68e-1)" "unprognostic (1.97e-1)" "unprognostic (1.69e-2)" "unprognostic (2.61e-1)" NFX1 "MGC20369, NFX2, TEG-42, Tex42" ENSG00000086102 "Nuclear transcription factor, X-box binding 1" Q12986 9 33290512-33371157 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, DNA-binding, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056310, HPA061382, HPA073519" Approved Supported "Nucleoplasm,Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 9: Non-specific - Receptor signaling" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 39 Nucleoplasm "Nucleoli, Plasma membrane, Cytosol" "HPA056310: , HPA061382: , HPA073519: " "unprognostic (1.36e-2)" "unprognostic (2.31e-1)" "unprognostic (3.13e-1)" "unprognostic (7.54e-2)" "unprognostic (7.43e-2)" "unprognostic (2.53e-3)" "unprognostic (1.93e-1)" "unprognostic (8.93e-2)" "unprognostic (8.23e-3)" "unprognostic (1.25e-2)" "validated prognostic favorable (2.44e-7)" "validated prognostic favorable (7.49e-5)" "unprognostic (3.88e-2)" "unprognostic (4.21e-2)" "unprognostic (1.11e-1)" "unprognostic (1.91e-1)" "unprognostic (5.19e-2)" "unprognostic (3.37e-1)" "unprognostic (2.00e-1)" "unprognostic (1.44e-2)" "unprognostic (1.51e-1)" "unprognostic (1.14e-1)" "unprognostic (5.62e-2)" "unprognostic (7.31e-2)" "unprognostic (6.31e-2)" "unprognostic (1.19e-1)" "unprognostic (1.60e-2)" "unprognostic (7.33e-2)" "unprognostic (1.65e-1)" "unprognostic (1.43e-1)" "unprognostic (1.42e-2)" NFXL1 HOZFP ENSG00000170448 "Nuclear transcription factor, X-box binding like 1" Q6ZNB6 4 47847233-47914667 "Predicted membrane proteins, Transcription factors" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 9 "Cardiomyocytes: 987.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059132 Approved Approved Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 22: Epididymis - Mixed function" "Cluster 2: Neurons - Nucleosome" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 10 Nucleoplasm "HPA059132: " "unprognostic (1.25e-2)" "unprognostic (4.73e-2)" "unprognostic (3.93e-2)" "unprognostic (5.58e-2)" "unprognostic (1.49e-1)" "unprognostic (1.03e-1)" "unprognostic (2.23e-1)" "unprognostic (9.94e-2)" "unprognostic (1.41e-1)" "unprognostic (3.04e-2)" "potential prognostic favorable (2.20e-4)" "unprognostic (1.34e-3)" "unprognostic (1.40e-1)" "unprognostic (4.15e-3)" "unprognostic (4.19e-2)" "unprognostic (1.30e-2)" "potential prognostic unfavorable (6.42e-5)" "unprognostic (8.33e-2)" "unprognostic (1.99e-1)" "unprognostic (3.95e-1)" "unprognostic (1.14e-1)" "unprognostic (5.36e-2)" "unprognostic (5.34e-3)" "unprognostic (2.15e-2)" "unprognostic (1.20e-2)" "unprognostic (1.63e-1)" "unprognostic (1.84e-1)" "unprognostic (1.27e-1)" "unprognostic (2.98e-1)" "unprognostic (3.85e-3)" "unprognostic (1.29e-1)" NFYA "CBF-B, HAP2, NF-YA" ENSG00000001167 "Nuclear transcription factor Y subunit alpha" P23511 6 41072974-41102403 "Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophil progenitors: 86.8;Neutrophils: 180.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009250, HPA050779" Enhanced Supported Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 11: White matter - Signal transduction" "Cluster 28: Non-specific - Nuclear processes" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 32 Nucleoplasm "CAB009250: , HPA050779: " "unprognostic (1.42e-2)" "unprognostic (4.21e-2)" "unprognostic (2.71e-2)" "unprognostic (8.62e-3)" "unprognostic (2.90e-1)" "unprognostic (1.20e-1)" "unprognostic (4.95e-1)" "unprognostic (1.61e-2)" "unprognostic (2.23e-2)" "unprognostic (3.23e-3)" "potential prognostic favorable (9.35e-4)" "unprognostic (5.70e-3)" "unprognostic (4.49e-2)" "unprognostic (2.14e-3)" "unprognostic (5.97e-2)" "unprognostic (1.35e-2)" "unprognostic (1.23e-2)" "unprognostic (3.08e-1)" "unprognostic (5.80e-2)" "unprognostic (2.67e-1)" "unprognostic (7.15e-2)" "unprognostic (2.37e-3)" "unprognostic (1.13e-3)" "unprognostic (3.33e-1)" "unprognostic (4.63e-3)" "unprognostic (1.46e-1)" "unprognostic (1.85e-2)" "unprognostic (4.05e-1)" "unprognostic (1.70e-1)" "unprognostic (3.16e-2)" "unprognostic (1.31e-1)" NFYB "CBF-A, HAP3, NF-YB" ENSG00000120837 "Nuclear transcription factor Y subunit beta" P25208 12 104117086-104138241 "Essential proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Syncytiotrophoblasts: 486.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004211, HPA065646" Supported Supported Nucleoplasm NA NA "Cluster 1: T-cells - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 22 Nucleoplasm "CAB004211: , HPA065646: " "unprognostic (7.37e-2)" "unprognostic (1.11e-2)" "unprognostic (3.73e-2)" "unprognostic (1.34e-2)" "unprognostic (3.79e-2)" "unprognostic (5.46e-2)" "unprognostic (1.05e-1)" "unprognostic (6.23e-2)" "unprognostic (1.08e-1)" "unprognostic (2.83e-1)" "unprognostic (6.04e-2)" "unprognostic (3.50e-2)" "unprognostic (2.81e-2)" "unprognostic (7.11e-2)" "unprognostic (4.13e-2)" "unprognostic (5.14e-2)" "unprognostic (3.82e-2)" "unprognostic (1.07e-1)" "unprognostic (3.19e-1)" "unprognostic (1.07e-1)" "unprognostic (3.32e-2)" "unprognostic (1.26e-1)" "unprognostic (1.85e-1)" "unprognostic (7.76e-2)" "unprognostic (1.53e-1)" "unprognostic (2.54e-2)" "unprognostic (2.95e-2)" "unprognostic (3.47e-3)" "unprognostic (3.77e-1)" "unprognostic (1.07e-1)" "unprognostic (9.70e-2)" NFYC "CBF-C, NF-YC" ENSG00000066136 "Nuclear transcription factor Y subunit gamma" Q13952 1 40691648-40771603 "Essential proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 281.0;Neutrophils: 364.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055011 Supported Nucleoplasm NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 53: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 24: Neutrophils - Innate immunity signal integration" 32 Nucleoplasm "HPA055011: " "unprognostic (3.34e-2)" "unprognostic (5.80e-2)" "unprognostic (1.36e-1)" "unprognostic (9.30e-2)" "unprognostic (7.02e-2)" "unprognostic (2.26e-1)" "unprognostic (1.06e-1)" "unprognostic (1.33e-2)" "unprognostic (5.75e-2)" "unprognostic (5.06e-2)" "potential prognostic favorable (1.10e-6)" "unprognostic (4.03e-3)" "potential prognostic favorable (6.19e-4)" "potential prognostic unfavorable (8.68e-7)" "unprognostic (2.98e-2)" "unprognostic (1.10e-1)" "unprognostic (8.82e-2)" "unprognostic (8.61e-2)" "unprognostic (6.18e-2)" "unprognostic (6.27e-2)" "unprognostic (2.77e-1)" "unprognostic (3.44e-1)" "unprognostic (8.17e-2)" "unprognostic (4.25e-2)" "unprognostic (6.71e-3)" "unprognostic (6.75e-2)" "unprognostic (4.55e-2)" "unprognostic (3.76e-2)" "unprognostic (3.44e-1)" "unprognostic (5.10e-2)" "unprognostic (7.11e-2)" NGB ENSG00000165553 Neuroglobin Q9NPG2 14 77265483-77271206 "Predicted intracellular proteins, Transporters" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 75.1" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 10.6;Brain excitatory neurons: 7.1;Brain inhibitory neurons: 5.4;Epididymal efferent duct ciliated cells: 6.3;Fallopian tube ciliated cells: 5.6;Oligodendrocyte progenitor cells: 10.0;Oocytes: 13.8;Other brain neurons: 37.9;Thymocytes: 9.3" "Cell type enhanced" "Detected in many" "thalamic excitatory: 21.0" "Cancer enhanced" "Detected in some" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 4.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.9;lung cancer: 1.0" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pituitary gland - Corticotropes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA042615, HPA058596" Enhanced Approved Cytosol NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 98: Neurons - Neurotransmission & signaling" 14 Cytosol "HPA042615: , HPA058596: " "unprognostic (8.34e-2)" "potential prognostic favorable (5.36e-4)" "unprognostic (2.68e-2)" "unprognostic (1.30e-1)" "unprognostic (1.25e-1)" NGDN "C14orf120, CANu1, DKFZP564O092, LCP5, lpd-2, NGD" ENSG00000129460 Neuroguidin Q8NEJ9 14 23469679-23509862 "Essential proteins, Predicted intracellular proteins" "Translation regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 119.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000944 Approved Approved Nucleoplasm,Nucleoli,Mitochondria Yes No "Cluster 3: Non-specific - Nuclear processes" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 17: Non-specific - RNA processing" 12 "Nucleoli, Mitochondria" Nucleoplasm "HPA000944: " "unprognostic (7.37e-3)" "unprognostic (2.18e-1)" "unprognostic (7.12e-2)" "unprognostic (3.42e-2)" "unprognostic (1.52e-1)" "unprognostic (1.89e-1)" "unprognostic (7.13e-2)" "unprognostic (1.85e-3)" "unprognostic (5.87e-3)" "unprognostic (6.00e-2)" "potential prognostic favorable (6.42e-7)" "unprognostic (1.10e-3)" "unprognostic (2.23e-1)" "unprognostic (3.34e-2)" "potential prognostic unfavorable (6.21e-6)" "unprognostic (1.89e-2)" "unprognostic (2.14e-3)" "unprognostic (1.34e-2)" "unprognostic (6.37e-2)" "unprognostic (1.61e-2)" "unprognostic (1.41e-1)" "unprognostic (1.63e-1)" "unprognostic (6.70e-2)" "unprognostic (7.01e-2)" "unprognostic (1.22e-1)" "unprognostic (4.58e-2)" "unprognostic (3.74e-2)" "unprognostic (2.69e-1)" "unprognostic (8.63e-2)" "unprognostic (9.91e-2)" "unprognostic (3.92e-2)" NGEF ARHGEF27 ENSG00000066248 "Neuronal guanine nucleotide exchange factor" Q8N5V2 2 232878701-233013256 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 54.1;brain: 139.7" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 50.9;Brain inhibitory neurons: 123.4;Colonocytes: 68.6;Enteric stem cells: 46.1;Enteric transient amplifying cells: 40.9;Enterocytes: 134.8;Foveolar cells: 42.0;Hepatocytes: 50.7;Paneth cells: 46.4;Proximal tubule cells: 56.2" "Cell type enhanced" "Detected in all" "medium spiny neuron: 319.9" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 58.2" "Group enriched" "Detected in all" 4 "basal ganglia: 380.4;cerebral cortex: 233.6;white matter: 165.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Skeletal muscle - Fibroblasts, Skin - Keratinocyte (other), Spleen - Smooth muscle cells, Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basal ganglia: 219.2;cerebral cortex: 173.3;hippocampal formation: 95.4" HPA008160 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Neurons - Synaptic function & neurogenesis" 12 "Plasma membrane, Cytosol" "HPA008160: " "unprognostic (2.74e-2)" "unprognostic (7.04e-2)" "unprognostic (5.71e-2)" "unprognostic (2.03e-1)" "unprognostic (2.00e-2)" "unprognostic (1.36e-1)" "unprognostic (7.93e-2)" "unprognostic (6.88e-2)" "unprognostic (3.60e-2)" "unprognostic (1.77e-1)" "unprognostic (4.52e-3)" "unprognostic (4.60e-2)" "unprognostic (3.35e-1)" "unprognostic (7.05e-2)" "potential prognostic unfavorable (1.37e-4)" "unprognostic (6.16e-2)" "unprognostic (7.06e-2)" "potential prognostic favorable (1.78e-4)" "unprognostic (2.29e-1)" "unprognostic (1.94e-2)" "unprognostic (5.27e-3)" "unprognostic (5.80e-2)" "unprognostic (1.37e-1)" "unprognostic (7.58e-2)" "unprognostic (2.17e-1)" "unprognostic (5.27e-2)" "unprognostic (4.92e-2)" "unprognostic (2.16e-1)" "unprognostic (2.40e-2)" "unprognostic (3.84e-2)" NGF NGFB ENSG00000134259 "Nerve growth factor" P01138 1 115285904-115338770 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Cancer-related genes, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 21.9;ovary: 19.3" "Cell type enhanced" "Detected in many" "Adipocytes: 65.3;Epicardial cells: 61.4;Fibro-adipogenic progenitors: 48.8;Fibroblasts: 59.5;Hepatic stellate cells: 129.1;Leydig cells: 111.9;Mesothelial cells: 76.1;Ovarian stromal cells: 38.0;Pericytes: 124.9;Podocytes: 53.4;Smooth muscle cells: 38.4;Vascular smooth muscle cells: 91.3" "Cell type enhanced" "Detected in many" "fibroblast: 60.5;LAMP5-LHX6 and Chandelier: 56.6" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 12.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 18.9" "Liver - Hepatic stellate cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted in other tissues" "Growth factor" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 103: Non-specific - Basic cellular processes" 11 "unprognostic (6.15e-3)" "unprognostic (7.97e-2)" "unprognostic (2.64e-1)" "unprognostic (5.01e-2)" "unprognostic (3.66e-1)" "potential prognostic unfavorable (4.57e-4)" "unprognostic (1.70e-1)" "unprognostic (1.16e-1)" "unprognostic (1.54e-3)" "potential prognostic unfavorable (6.00e-6)" "unprognostic (1.26e-1)" "unprognostic (1.75e-1)" "unprognostic (1.91e-2)" "unprognostic (1.31e-1)" "unprognostic (1.27e-1)" "unprognostic (4.00e-2)" "unprognostic (3.04e-1)" "unprognostic (1.96e-1)" "unprognostic (2.45e-1)" "unprognostic (1.64e-1)" NGFR "CD271, p75NTR, TNFRSF16" ENSG00000064300 "Nerve growth factor receptor" P08138 17 49495293-49515008 "Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Apoptosis, Biological rhythms, Differentiation, Neurogenesis" "Developmental protein, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 43.9;Breast myoepithelial cells: 54.2;Epididymal basal cells: 36.2;Hepatic stellate cells: 32.3;Leydig cells: 111.7;Müller glia: 157.1;Peritubular myoid cells: 30.4;Respiratory ionocytes: 76.2;Salivary ionocytes: 167.2;Salivary myoepithelial cells: 46.5;Schwann cells: 82.1" "Group enriched" "Detected in some" 4 "fibroblast: 9.4;oligodendrocyte: 11.4" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 64.8" "Region enhanced" "Detected in all" "cerebral cortex: 187.1" "Immune cell enriched" "Detected in single" 8 "plasmacytoid DC: 1.2" "Lineage enriched" "Detected in single" 8 "dendritic cells: 1.2" "Cancer enhanced" "Detected in many" "Sarcoma: 69.2;skin cancer: 133.4" "Adrenal gland - Fibroblasts, Lung - Fibroblasts_2, Pituitary gland - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "basal ganglia: 13.5" "CAB000143, CAB001995, HPA004765" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 4600000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 69: Skin cancer - ECM organization" "Cluster 11: Muller glia cells - Retinal homeostasis" 35 "Nucleoplasm, Plasma membrane" "CAB000143: , CAB001995: , HPA004765: " "unprognostic (4.27e-1)" "unprognostic (5.70e-3)" "unprognostic (1.33e-1)" "unprognostic (6.45e-3)" "unprognostic (2.03e-2)" "unprognostic (4.75e-2)" "unprognostic (1.21e-2)" "unprognostic (9.19e-2)" "unprognostic (1.91e-1)" "unprognostic (1.65e-1)" "unprognostic (1.26e-3)" "potential prognostic favorable (3.07e-6)" "unprognostic (2.19e-2)" "unprognostic (1.16e-1)" "potential prognostic favorable (6.12e-4)" "unprognostic (4.25e-2)" "unprognostic (1.95e-1)" "unprognostic (1.38e-2)" "unprognostic (2.02e-1)" "unprognostic (2.15e-2)" "unprognostic (1.36e-1)" "unprognostic (3.37e-2)" "unprognostic (4.98e-2)" "unprognostic (4.38e-2)" "unprognostic (1.91e-2)" "unprognostic (4.31e-2)" "unprognostic (1.73e-2)" "unprognostic (2.79e-2)" "unprognostic (3.41e-2)" "unprognostic (5.25e-3)" "unprognostic (3.29e-2)" NGLY1 "FLJ11005, PNG-1, PNG1" ENSG00000151092 "N-glycanase 1" Q96IV0 3 25718944-25790039 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 729.2;Late spermatids: 1594.6;Pancreatic acinar cells: 463.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - B-cells (Spleen), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036825 Approved NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 24 "HPA036825: " "unprognostic (2.20e-1)" "unprognostic (6.28e-2)" "unprognostic (4.61e-2)" "unprognostic (2.90e-1)" "potential prognostic favorable (3.81e-5)" "unprognostic (1.54e-1)" "unprognostic (2.35e-1)" "unprognostic (6.25e-2)" "unprognostic (7.80e-2)" "unprognostic (9.88e-2)" "potential prognostic favorable (1.56e-5)" "unprognostic (8.76e-2)" "unprognostic (3.88e-2)" "unprognostic (1.23e-2)" "potential prognostic unfavorable (8.91e-4)" "unprognostic (6.33e-3)" "unprognostic (1.05e-1)" "unprognostic (2.81e-1)" "unprognostic (2.73e-2)" "unprognostic (1.33e-1)" "unprognostic (4.92e-3)" "unprognostic (2.53e-1)" "unprognostic (2.92e-2)" "unprognostic (4.73e-2)" "unprognostic (2.29e-3)" "unprognostic (1.20e-1)" "unprognostic (4.96e-2)" "unprognostic (2.28e-2)" "unprognostic (9.70e-2)" "unprognostic (1.31e-1)" "unprognostic (3.47e-1)" NGRN DSC92 ENSG00000182768 "Neugrin, neurite outgrowth associated" Q9NPE2 15 90265659-90275778 "Predicted intracellular proteins" Differentiation "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 402.7" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 5.1;Brain inhibitory neurons: 4.5;Endometrial secretory cells: 2.9;Medullary thymic epithelial cells: 2.4;Oocytes: 4.6;Other brain neurons: 8.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041367, HPA076267" Supported Supported "Nucleoplasm,Cytokinetic bridge,Mitochondria" "Intracellular and membrane" "Developmental protein" Yes No "Cluster 3: Non-specific - Nuclear processes" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 98: Neurons - Neurotransmission & signaling" 58 Mitochondria "Nucleoplasm, Cytokinetic bridge" "HPA041367: , HPA076267: " "unprognostic (4.07e-3)" "unprognostic (9.11e-2)" "unprognostic (3.21e-1)" "unprognostic (8.28e-2)" "unprognostic (1.30e-3)" "unprognostic (2.65e-1)" "unprognostic (6.28e-2)" "unprognostic (1.15e-3)" "potential prognostic unfavorable (2.33e-4)" "unprognostic (3.00e-2)" "unprognostic (1.62e-1)" "unprognostic (1.42e-3)" "unprognostic (1.08e-1)" "unprognostic (1.04e-1)" "potential prognostic unfavorable (4.27e-7)" "unprognostic (3.58e-2)" "unprognostic (1.87e-1)" "unprognostic (1.09e-1)" "unprognostic (4.16e-2)" "unprognostic (3.09e-3)" "unprognostic (1.53e-1)" "unprognostic (1.04e-1)" "unprognostic (7.52e-2)" "unprognostic (2.74e-1)" "unprognostic (4.58e-2)" "unprognostic (1.11e-1)" "unprognostic (4.69e-3)" "unprognostic (9.54e-2)" "unprognostic (6.02e-2)" "unprognostic (1.37e-1)" "unprognostic (4.32e-1)" NHEJ1 "Cernunnos, FLJ12610, XLF" ENSG00000187736 "Non-homologous end joining factor 1" Q9H9Q4 2 219069355-219160869 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" DNA-binding "Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 29.0;Enteric transient amplifying cells: 11.1;Enterocytes: 14.7;Goblet cells: 22.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012334, HPA043869" Approved Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA 11000 "Cluster 16: Non-specific - Cell proliferation" "Cluster 39: Testis - Nuclear processes" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 70: Intestinal goblet cells - Mucin production" 8 Nucleoplasm "Nucleoli fibrillar center" "CAB012334: , HPA043869: " "unprognostic (4.64e-2)" "unprognostic (3.01e-2)" "potential prognostic favorable (2.12e-4)" "potential prognostic unfavorable (8.43e-4)" "unprognostic (6.62e-2)" "unprognostic (4.72e-2)" "unprognostic (1.11e-1)" "unprognostic (8.23e-2)" "unprognostic (1.75e-1)" "unprognostic (1.36e-1)" "validated prognostic favorable (3.29e-6)" "validated prognostic favorable (2.42e-4)" "unprognostic (1.03e-1)" "potential prognostic unfavorable (9.92e-5)" "unprognostic (2.90e-3)" "unprognostic (5.59e-2)" "unprognostic (8.23e-2)" "unprognostic (1.24e-2)" "unprognostic (1.09e-1)" "unprognostic (5.40e-2)" "unprognostic (2.15e-1)" "unprognostic (7.19e-2)" "unprognostic (1.32e-1)" "unprognostic (1.46e-2)" "unprognostic (1.42e-1)" "unprognostic (1.94e-1)" "unprognostic (6.16e-2)" "unprognostic (4.98e-2)" "unprognostic (1.48e-1)" "unprognostic (4.14e-1)" "unprognostic (1.54e-1)" NHLH1 "bHLHa35, HEN1, NSCL, NSCL1" ENSG00000171786 "Nescient helix-loop-helix 1" Q02575 1 160367071-160372846 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.7" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 2.1;Kupffer cells: 3.1;Mesothelial cells: 4.8;monocytes: 2.2;Neutrophil progenitors: 1.9;Neutrophils: 9.5;pDCs: 2.0;Thymocytes: 1.7" "Low cell type specificity" "Detected in some" "Group enriched" "Detected in some" 5 "Bladder Urothelial Carcinoma (TCGA): 1.7;Glioblastoma Multiforme (TCGA): 3.8;Testicular Germ Cell Tumor (TCGA): 1.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 3.8" "Region enhanced" "Detected in single" "hippocampal formation: 1.0" "Region enriched" "Detected in some" 13 "cerebellum: 25.8" HPA017943 Approved "Golgi apparatus" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 24: Neutrophils - Innate immunity signal integration" 9 "Golgi apparatus" "HPA017943: " "unprognostic (2.94e-3)" "unprognostic (1.18e-2)" "unprognostic (1.40e-1)" "unprognostic (1.34e-2)" "unprognostic (2.12e-1)" NHLH2 "bHLHa34, HEN2, NSCL2" ENSG00000177551 "Nescient helix-loop-helix 2" Q02577 1 115836377-115843917 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 6.6;esophagus: 2.2;retina: 1.9;skin 1: 3.1" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 4.3;Brain excitatory neurons: 8.0;Breast myoepithelial cells: 11.2;Early primary spermatocytes: 5.3;Ependymal cells: 7.4;Epididymal basal cells: 4.3;Esophageal basal cells: 7.4;Esophageal suprabasal cells: 4.7;Oligodendrocytes: 7.3;Other brain neurons: 6.0;Retinal amacrine cells: 5.5;Retinal ganglion cells: 3.9;Suprabasal keratinocytes: 3.9;Thymic myoid cells: 19.0;Undifferentiated spermatogonia: 5.4" "Cell type enhanced" "Detected in many" "thalamic excitatory: 27.7" "Cancer enhanced" "Detected in some" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 1.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Neuroblastoma: 7.4" "Prostate - Urothelial cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA055238 Uncertain Approved "Nucleoplasm,Nuclear bodies" Yes NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 44: Non-specific - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 98: Neurons - Neurotransmission & signaling" 12 "Nuclear bodies" Nucleoplasm "HPA055238: " "unprognostic (1.04e-1)" "unprognostic (2.73e-2)" "unprognostic (9.06e-2)" NHLRC1 "bA204B7.2, EPM2B" ENSG00000187566 "NHL repeat containing E3 ubiquitin protein ligase 1" Q6VVB1 6 18120440-18122677 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Autophagy, Ubl conjugation pathway" Transferase "Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hepatocytes: 4.5;Megakaryocyte-Erythroid progenitors: 5.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" HPA078292 Supported Nucleoplasm,Cytosol NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 76: Non-specific - Metabolism" "Cluster 9: Non-specific - Receptor signaling" "Cluster 4: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 14 Nucleoplasm Cytosol "HPA078292: " "unprognostic (1.70e-2)" "unprognostic (2.41e-1)" "unprognostic (4.60e-3)" "unprognostic (5.91e-3)" "unprognostic (3.34e-1)" "potential prognostic favorable (8.67e-4)" "unprognostic (5.88e-2)" "unprognostic (1.16e-2)" "unprognostic (1.34e-1)" "unprognostic (1.53e-1)" "unprognostic (3.04e-2)" "unprognostic (8.68e-2)" "unprognostic (1.83e-2)" "unprognostic (2.80e-2)" "unprognostic (5.25e-2)" "unprognostic (5.91e-2)" "unprognostic (1.50e-1)" "unprognostic (3.50e-1)" "unprognostic (2.43e-2)" "unprognostic (5.08e-3)" "unprognostic (1.92e-1)" "unprognostic (2.63e-3)" "potential prognostic favorable (6.86e-4)" "unprognostic (1.45e-1)" "potential prognostic favorable (7.78e-4)" "unprognostic (1.63e-2)" "unprognostic (7.34e-2)" "unprognostic (2.89e-1)" "unprognostic (9.11e-2)" "unprognostic (2.28e-2)" "unprognostic (1.23e-1)" NHLRC2 "DKFZp779F115, FLJ20147, FLJ25621, FLJ33312, MGC45492" ENSG00000196865 "NHL repeat containing 2" Q8NBF2 10 113854661-113917194 "Disease related genes, Predicted intracellular proteins" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 296.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038493, HPA057564" Approved Approved Nucleoplasm NA NA 140000 "Cluster 32: Basophils - Transcription" "Cluster 35: Non-specific - Mixed function" "Cluster 55: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 55: Myocytes - Oxidative muscle function" 8 Nucleoplasm "HPA038493: , HPA057564: " "unprognostic (6.98e-3)" "unprognostic (2.53e-1)" "unprognostic (3.13e-1)" "unprognostic (6.45e-2)" "unprognostic (1.11e-1)" "unprognostic (1.31e-2)" "unprognostic (8.26e-2)" "unprognostic (6.35e-3)" "unprognostic (6.87e-2)" "unprognostic (4.53e-2)" "unprognostic (2.15e-3)" "unprognostic (1.40e-3)" "unprognostic (1.31e-1)" "unprognostic (5.79e-2)" "unprognostic (2.62e-2)" "unprognostic (3.46e-1)" "unprognostic (2.72e-1)" "unprognostic (2.16e-1)" "unprognostic (1.18e-1)" "unprognostic (1.63e-1)" "potential prognostic unfavorable (1.80e-5)" "unprognostic (2.96e-2)" "unprognostic (9.16e-3)" "unprognostic (1.34e-1)" "unprognostic (9.22e-2)" "unprognostic (3.53e-3)" "unprognostic (1.76e-1)" "unprognostic (1.88e-1)" "unprognostic (2.50e-1)" "unprognostic (9.54e-2)" "unprognostic (7.86e-2)" NHLRC3 ENSG00000188811 "NHL repeat containing 3" Q5JS37 13 39038306-39050109 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013738 Uncertain "Secreted to blood" "No annotated function" NA NA 460000 "Cluster 33: Non-specific - ATP binding" "Cluster 70: Non-specific - Protein processing" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 19: Non-specific - Unknown function" "Cluster 89: Adipocytes - Lipid metabolism" 2 "HPA013738: " "unprognostic (5.00e-3)" "unprognostic (2.43e-1)" "unprognostic (1.58e-1)" "unprognostic (4.13e-3)" "unprognostic (2.29e-1)" "unprognostic (1.81e-1)" "unprognostic (2.99e-2)" "unprognostic (2.10e-1)" "unprognostic (1.16e-1)" "unprognostic (2.07e-1)" "unprognostic (6.63e-3)" "unprognostic (2.65e-1)" "potential prognostic favorable (1.47e-4)" "unprognostic (3.18e-1)" "unprognostic (1.55e-1)" "unprognostic (1.16e-1)" "unprognostic (7.18e-2)" "unprognostic (3.74e-2)" "unprognostic (1.44e-1)" "unprognostic (5.30e-2)" "unprognostic (2.41e-2)" "unprognostic (9.82e-2)" "unprognostic (1.90e-1)" "unprognostic (1.79e-1)" "unprognostic (4.61e-2)" "unprognostic (3.09e-1)" "unprognostic (1.62e-1)" "unprognostic (7.82e-3)" "unprognostic (4.96e-2)" "unprognostic (9.35e-2)" "unprognostic (1.63e-1)" NHLRC4 ENSG00000257108 "NHL repeat containing 4" P0CG21 16 567005-569495 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 11.0;kidney: 9.5" "Cell type enhanced" "Detected in single" "Fallopian tube ciliated cells: 1.9" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Breast Invasive Carcinoma (TCGA): 3.6;Kidney Chromophobe (TCGA): 12.3;Uterine Corpus Endometrial Carcinoma (TCGA): 4.4" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "eosinophil: 2.3" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Leukemia: 2.8" "Kidney - Ascending Loop of Henle cells, Lung - Respiratory ciliated cells, Pituitary gland - Thyrotropes, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in single" HPA077301 Approved Mitochondria NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 3: Choroid plexus - Cilium" "Cluster 47: Leukemia - Hemostasis" "Cluster 107: Ciliated cells - Cilia assembly & function" 15 Mitochondria "HPA077301: " "unprognostic (1.36e-1)" "unprognostic (3.34e-1)" "potential prognostic favorable (7.20e-4)" "unprognostic (7.86e-3)" "unprognostic (4.78e-2)" "unprognostic (5.42e-2)" "unprognostic (1.50e-2)" "unprognostic (7.24e-2)" "unprognostic (1.38e-1)" NHP2 "FLJ20479, NOLA2" ENSG00000145912 "NHP2 ribonucleoprotein" Q9NX24 5 178149463-178153894 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribosome biogenesis, rRNA processing" "Ribonucleoprotein, RNA-binding" "Disease variant, Dyskeratosis congenita" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 677.5;Esophageal basal cells: 645.7;Esophageal suprabasal cells: 750.6;Extravillous trophoblasts: 402.8;Migrating cytotrophoblasts: 379.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044171, HPA050400" Enhanced NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 85: Squamous epithelial cells - Keratinization" 21 "HPA044171: , HPA050400: " "potential prognostic unfavorable (5.29e-4)" "unprognostic (1.05e-1)" "unprognostic (1.06e-2)" "unprognostic (2.15e-2)" "unprognostic (9.32e-2)" "unprognostic (5.24e-2)" "unprognostic (1.76e-1)" "unprognostic (3.58e-1)" "unprognostic (3.38e-2)" "unprognostic (7.16e-2)" "potential prognostic favorable (8.31e-4)" "unprognostic (1.35e-1)" "unprognostic (5.21e-3)" "validated prognostic unfavorable (1.06e-5)" "validated prognostic unfavorable (2.09e-6)" "unprognostic (4.81e-3)" "unprognostic (4.44e-2)" "unprognostic (1.49e-1)" "unprognostic (2.85e-1)" "unprognostic (1.11e-2)" "unprognostic (7.07e-3)" "unprognostic (1.03e-1)" "unprognostic (3.72e-1)" "unprognostic (3.49e-2)" "unprognostic (3.94e-2)" "unprognostic (2.78e-1)" "unprognostic (5.26e-2)" "unprognostic (2.18e-1)" "unprognostic (3.61e-1)" "unprognostic (2.26e-1)" "unprognostic (9.68e-2)" NHS ENSG00000188158 "NHS actin remodeling regulator" Q6T4R5 X 17375200-17735994 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 943.6;Endometrial glandular cells: 697.0;Loop of henle epithelial cells: 588.4;Pituicytes/FSCs: 936.1;Proximal tubule cells: 1595.4;Sertoli cells: 743.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Kidney - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA031497, HPA076257" Uncertain Supported "Cell Junctions" NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 1: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 88: Proximal tubular cells - Transmembrane transport" 4 "Cell Junctions" "HPA031497: , HPA076257: " "unprognostic (1.32e-3)" "unprognostic (2.18e-2)" "unprognostic (1.53e-1)" "unprognostic (2.45e-1)" "unprognostic (2.78e-2)" "unprognostic (3.57e-1)" "unprognostic (2.78e-1)" "unprognostic (2.79e-2)" "unprognostic (9.77e-2)" "unprognostic (1.53e-1)" "unprognostic (1.90e-2)" "unprognostic (3.27e-1)" "potential prognostic favorable (5.60e-4)" "unprognostic (1.21e-1)" "unprognostic (5.51e-2)" "unprognostic (2.44e-3)" "unprognostic (1.48e-2)" "unprognostic (4.65e-2)" "unprognostic (1.74e-3)" "unprognostic (5.85e-2)" "unprognostic (3.91e-1)" "unprognostic (2.89e-1)" "unprognostic (5.02e-2)" "unprognostic (1.25e-1)" "unprognostic (7.59e-2)" NHSL1 "bA43P8.1, C6orf63, KIAA1357" ENSG00000135540 "NHS like 1" Q5SYE7 6 138422043-138692571 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 21.7" "Cell type enhanced" "Detected in many" "Astrocytes: 939.5;Basal keratinocytes: 454.1;Bergmann glia: 1135.1;Choroid plexus epithelial cells: 475.5;Esophageal apical cells: 825.8;Ocular epithelial cells: 482.5;Suprabasal keratinocytes: 531.3;Syncytiotrophoblasts: 677.8" "Cell type enhanced" "Detected in all" "astrocyte: 944.8;Bergmann glia: 1279.1;choroid plexus epithelial cell: 518.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.6;non-classical monocyte: 1.7" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Liver - Hepatocytes, Skeletal muscle - Fibroblasts, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029966, HPA029967" Uncertain Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 77: Intestine - Digestion" "Cluster 44: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 28: Astrocytes - Homeostasis & neuron support" 11 "Nuclear membrane" Nucleoplasm "HPA029966: , HPA029967: " "unprognostic (4.32e-2)" "unprognostic (1.75e-1)" "unprognostic (1.59e-1)" "unprognostic (5.85e-2)" "unprognostic (1.23e-2)" "unprognostic (5.83e-2)" "unprognostic (2.40e-2)" "unprognostic (3.91e-2)" "unprognostic (1.37e-1)" "unprognostic (7.73e-2)" "potential prognostic favorable (5.91e-5)" "unprognostic (3.04e-3)" "unprognostic (2.06e-1)" "unprognostic (2.35e-1)" "unprognostic (1.35e-1)" "unprognostic (1.13e-1)" "unprognostic (2.07e-1)" "unprognostic (1.24e-2)" "unprognostic (1.88e-2)" "unprognostic (1.51e-2)" "unprognostic (1.84e-1)" "unprognostic (2.61e-1)" "unprognostic (2.65e-1)" "unprognostic (1.17e-1)" "unprognostic (1.46e-2)" "unprognostic (2.21e-1)" "unprognostic (1.15e-1)" "unprognostic (5.02e-2)" "unprognostic (5.07e-1)" "unprognostic (4.50e-2)" "unprognostic (9.27e-2)" NHSL2 ENSG00000204131 "NHS like 2" Q5HYW2 X 71910845-72161750 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.2" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 112.0;Choroid plexus epithelial cells: 934.7;Epicardial cells: 116.0;Fibro-adipogenic progenitors: 172.6;Mesothelial cells: 132.4;Neutrophils: 255.3;Pituicytes/FSCs: 259.7;Sertoli cells: 105.8" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 668.4" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 6.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 14.4;neutrophil: 15.7" "Group enriched" "Detected in many" 4 "dendritic cells: 4.1;granulocytes: 15.7;monocytes: 7.1" "Cancer enhanced" "Detected in some" "Neuroblastoma: 10.8;testis cancer: 6.5" "Liver - Vascular endothelial cells, Spleen - Neutrophils_2, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049771, HPA075115" Uncertain Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 74: Non-specific - Signal transduction" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 32 "Plasma membrane, Cell Junctions" Nucleoplasm "HPA049771: , HPA075115: " "unprognostic (6.90e-2)" "unprognostic (2.51e-2)" "unprognostic (2.06e-1)" "unprognostic (4.59e-2)" "unprognostic (2.01e-1)" "unprognostic (2.46e-2)" "validated prognostic favorable (2.69e-5)" "validated prognostic favorable (3.17e-4)" "unprognostic (2.68e-2)" "unprognostic (6.19e-2)" "unprognostic (2.86e-1)" "unprognostic (1.55e-1)" "unprognostic (1.34e-2)" "unprognostic (1.13e-1)" "unprognostic (2.00e-1)" "unprognostic (1.70e-1)" "unprognostic (4.56e-2)" "unprognostic (3.83e-3)" "unprognostic (5.36e-2)" "unprognostic (1.82e-2)" "unprognostic (1.45e-2)" NIBAN1 "C1orf24, FAM129A, GIG39, NIBAN" ENSG00000135842 "Niban apoptosis regulator 1" Q9BZQ8 1 184790724-184974508 "Cancer-related genes, Predicted intracellular proteins" "Stress response, Translation regulation" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 153.6" "Cell type enriched" "Detected in many" 5 "Neutrophils: 4383.2" "Cell type enhanced" "Detected in many" "leukocyte: 227.2;vascular associated smooth muscle cell: 494.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 72.3" "Lineage enriched" "Detected in all" 6 "granulocytes: 72.3" "Low cancer specificity" "Detected in all" "Adipose visceral - Smooth muscle cells, Breast - Breast myoepithelial cells, Prostate - Smooth muscle cells, Spleen - Neutrophils_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA028172, HPA028231, HPA028657" Approved Supported "Plasma membrane,Cytosol" NA NA 170000 "Cluster 35: Neutrophils - Protein binding" "Cluster 35: Non-specific - Mixed function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 24: Neutrophils - Innate immunity signal integration" 9 "Plasma membrane, Cytosol" "HPA028172: , HPA028231: , HPA028657: " "unprognostic (7.63e-2)" "unprognostic (3.45e-2)" "unprognostic (2.43e-1)" "unprognostic (6.50e-2)" "unprognostic (1.42e-1)" "unprognostic (2.80e-1)" "unprognostic (1.49e-2)" "unprognostic (3.37e-1)" "potential prognostic unfavorable (4.41e-6)" "unprognostic (1.94e-2)" "unprognostic (1.39e-1)" "unprognostic (2.49e-1)" "unprognostic (1.48e-2)" "unprognostic (2.92e-2)" "unprognostic (1.10e-1)" "unprognostic (1.86e-1)" "unprognostic (1.50e-1)" "unprognostic (4.44e-2)" "unprognostic (4.29e-3)" "unprognostic (3.17e-1)" "unprognostic (2.71e-2)" "unprognostic (6.33e-2)" "unprognostic (1.53e-3)" "unprognostic (8.15e-2)" "unprognostic (2.50e-1)" "unprognostic (2.05e-3)" "unprognostic (1.17e-1)" "unprognostic (4.32e-2)" "unprognostic (1.55e-1)" NIBAN2 "bA356B19.6, C9orf88, DKFZP434H0820, FAM129B, FLJ13518, FLJ22151, FLJ22298, MINERVA" ENSG00000136830 "Niban apoptosis regulator 2" Q96TA1 9 127505339-127578989 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 591.8" "Cell type enriched" "Detected in many" 4 "Esophageal apical cells: 2283.1" "Cell type enhanced" "Detected in many" "endothelial cell: 56.2;pericyte: 55.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "classical monocyte: 1.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021284, HPA021417, HPA023261, HPA024312" Uncertain Enhanced "Nucleoplasm,Plasma membrane,Cytosol" NA NA 980000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 19 "Plasma membrane, Cytosol" Nucleoplasm "HPA021284: , HPA021417: , HPA023261: , HPA024312: " "unprognostic (1.37e-1)" "unprognostic (1.34e-3)" "unprognostic (1.91e-2)" "unprognostic (1.05e-1)" "unprognostic (1.20e-3)" "unprognostic (2.69e-2)" "unprognostic (1.51e-1)" "unprognostic (1.52e-1)" "unprognostic (1.98e-1)" "unprognostic (4.89e-3)" "unprognostic (9.03e-2)" "unprognostic (1.41e-1)" "unprognostic (5.37e-2)" "unprognostic (4.14e-3)" "potential prognostic unfavorable (8.43e-4)" "unprognostic (5.40e-3)" "unprognostic (6.67e-2)" "unprognostic (8.11e-3)" "unprognostic (1.28e-1)" "unprognostic (2.55e-3)" "unprognostic (2.11e-2)" "unprognostic (8.13e-2)" "unprognostic (5.21e-2)" "unprognostic (2.87e-1)" "unprognostic (2.97e-1)" "unprognostic (1.58e-2)" "unprognostic (2.38e-1)" "unprognostic (2.06e-1)" "unprognostic (8.50e-2)" NIBAN3 "BCNP1, FAM129C, FLJ39802" ENSG00000167483 "Niban apoptosis regulator 3" Q86XR2 19 17523301-17553839 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 24 "bone marrow: 14.5;intestine: 17.1;lymphoid tissue: 37.9" "Group enriched" "Detected in many" 8 "B-cells: 260.8;pDCs: 504.8" "Cell type enhanced" "Detected in many" "leukocyte: 9.9" "Cancer enhanced" "Detected in single" "Pancreatic Adenocarcinoma (TCGA): 1.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 380 "memory B-cell: 32.0;naive B-cell: 52.3;plasmacytoid DC: 110.9" "Group enriched" "Detected in many" 477 "B-cells: 52.3;dendritic cells: 110.9" "Group enriched" "Detected in some" 47 "Leukemia: 38.5;lymphoma: 69.0" "Lung - B-cells (Lung), Minor Salivary Gland - T-cells, Spleen - B-cells (Spleen), Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA043277 Approved Approved Cytosol NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 2 Cytosol "HPA043277: " "unprognostic (4.27e-2)" "unprognostic (5.41e-3)" NICN1 MGC12936 ENSG00000145029 "Nicolin 1, tubulin polyglutamylase complex subunit" Q9BSH3 3 49422333-49429326 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Astrocytes: 2.4;Bergmann glia: 3.1;Brain excitatory neurons: 2.8;Brain inhibitory neurons: 2.9;Choroid plexus epithelial cells: 1.8;Ependymal cells: 1.9;Microglia: 2.8;Oligodendrocyte progenitor cells: 2.5;Oligodendrocytes: 1.9;Other brain neurons: 2.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "testis cancer: 20.4" "Skeletal muscle - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058014 Supported Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 65: Brain - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 98: Neurons - Neurotransmission & signaling" 11 Nucleoplasm "HPA058014: " "unprognostic (1.35e-2)" "unprognostic (7.69e-2)" "unprognostic (1.85e-2)" "unprognostic (4.14e-1)" "unprognostic (1.73e-1)" "unprognostic (1.77e-1)" "unprognostic (4.84e-2)" "unprognostic (1.50e-1)" "unprognostic (7.08e-2)" "unprognostic (1.84e-1)" "validated prognostic favorable (3.51e-4)" "validated prognostic favorable (7.55e-6)" "potential prognostic favorable (2.15e-5)" "unprognostic (1.37e-1)" "unprognostic (5.77e-2)" "unprognostic (4.45e-2)" "unprognostic (3.60e-1)" "unprognostic (6.02e-2)" "unprognostic (1.17e-3)" "unprognostic (2.07e-2)" "unprognostic (2.34e-1)" "unprognostic (4.84e-3)" "unprognostic (2.00e-1)" "unprognostic (2.61e-1)" "unprognostic (4.10e-2)" "unprognostic (2.51e-1)" "unprognostic (7.27e-2)" "unprognostic (3.34e-1)" "unprognostic (1.94e-1)" "unprognostic (2.29e-2)" "unprognostic (5.25e-1)" NID1 "entactin, NID" ENSG00000116962 "Nidogen 1" P14543 1 235975830-236065109 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 216.7" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 295.2;Decidual stromal cells: 278.9;Endometrial stromal cells: 478.1;Fibro-adipogenic progenitors: 219.3;Fibroblasts: 541.9;Hepatic stellate cells: 335.6;Leydig cells: 272.4;Parietal cells: 175.0;Pericytes: 407.2;Peritubular myoid cells: 201.4;Smooth muscle cells: 186.6;Vascular smooth muscle cells: 157.0" "Cell type enhanced" "Detected in many" "fibroblast: 284.6;pericyte: 269.7;vascular associated smooth muscle cell: 122.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 16 "classical monocyte: 5.7;intermediate monocyte: 11.2;myeloid DC: 4.4;non-classical monocyte: 7.3" "Group enriched" "Detected in many" 17 "dendritic cells: 4.4;monocytes: 11.2" "Cancer enhanced" "Detected in many" "Rhabdoid: 108.0" "Adrenal gland - Fibroblasts, Minor Salivary Gland - Macrophages, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010044, HPA065049" Approved Uncertain "Vesicles,Mitotic spindle" "Secreted to extracellular matrix" "Cell adhesion" Yes NA 180000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 2 Vesicles "Mitotic spindle" "CAB010044: , HPA065049: " "unprognostic (9.66e-2)" "unprognostic (1.67e-1)" "unprognostic (2.27e-1)" "unprognostic (3.22e-3)" "unprognostic (1.72e-1)" "unprognostic (4.16e-2)" "unprognostic (3.37e-1)" "unprognostic (2.99e-2)" "unprognostic (3.99e-2)" "unprognostic (2.06e-2)" "potential prognostic favorable (5.45e-4)" "unprognostic (2.84e-2)" "potential prognostic unfavorable (8.48e-5)" "unprognostic (1.04e-3)" "potential prognostic unfavorable (1.84e-4)" "unprognostic (1.50e-2)" "unprognostic (3.02e-3)" "unprognostic (1.47e-1)" "unprognostic (1.37e-1)" "unprognostic (4.11e-2)" "unprognostic (2.01e-2)" "unprognostic (1.65e-1)" "unprognostic (3.87e-1)" "unprognostic (2.25e-1)" "unprognostic (4.75e-2)" "unprognostic (3.89e-2)" "unprognostic (7.22e-2)" "unprognostic (8.78e-3)" "unprognostic (1.19e-1)" "unprognostic (6.54e-2)" "unprognostic (2.30e-2)" NID2 ENSG00000087303 "Nidogen 2" Q14112 14 52004809-52069059 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 57.9;placenta: 57.1" "Cell type enhanced" "Detected in many" "Adipocytes: 41.5;Cardiomyocytes: 72.4;Choroid plexus epithelial cells: 97.5;Epicardial cells: 70.5;Fibro-adipogenic progenitors: 93.2;Fibroblasts: 53.8;Hepatic stellate cells: 58.1;Mesothelial cells: 37.7;Ovarian stromal cells: 33.6;Pericytes: 75.9;Schwann cells: 35.5" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 86.6;fibroblast: 182.5" "Cancer enhanced" "Detected in all" "Thyroid Carcinoma (TCGA): 48.6" "Region enriched" "Detected in all" 18 "choroid plexus: 97.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "ovarian cancer: 50.3" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA052460, HPA058772" Enhanced Enhanced "Plasma membrane" "Secreted to extracellular matrix" "Cell adhesion" NA NA 6900000 "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 36: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 108: Fibroblasts - ECM organization" 6 "Plasma membrane" "HPA052460: , HPA058772: " "unprognostic (1.03e-1)" "unprognostic (7.81e-2)" "unprognostic (7.41e-2)" "potential prognostic unfavorable (1.09e-4)" "unprognostic (1.57e-1)" "unprognostic (2.15e-1)" "unprognostic (9.68e-2)" "unprognostic (1.49e-1)" "unprognostic (2.50e-1)" "unprognostic (6.38e-2)" "unprognostic (4.65e-3)" "unprognostic (7.27e-3)" "unprognostic (1.56e-2)" "unprognostic (5.96e-2)" "unprognostic (8.47e-2)" "unprognostic (1.02e-3)" "potential prognostic unfavorable (2.36e-4)" "unprognostic (5.80e-2)" "unprognostic (1.14e-1)" "unprognostic (5.49e-2)" "unprognostic (1.30e-2)" "unprognostic (4.61e-2)" "unprognostic (9.09e-2)" "unprognostic (9.55e-2)" "unprognostic (1.98e-1)" "unprognostic (1.53e-2)" "unprognostic (1.61e-2)" "unprognostic (2.27e-3)" "unprognostic (4.79e-2)" "unprognostic (1.66e-1)" "unprognostic (3.83e-2)" NIF3L1 "ALS2CR1, CALS-7, MDS015" ENSG00000196290 "NGG1 interacting factor 3 like 1" Q9GZT8 2 200889327-200903938 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 105.9;Retinal bipolar cells: 68.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Stomach - Mitotic cells (Stomach), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036335, HPA036336, HPA061466" Supported Approved Vesicles NA NA 6000000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 61: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 55 Vesicles "HPA036335: , HPA036336: , HPA061466: " "unprognostic (3.36e-2)" "potential prognostic unfavorable (1.09e-4)" "unprognostic (1.78e-1)" "unprognostic (2.00e-1)" "unprognostic (3.90e-2)" "unprognostic (2.46e-1)" "unprognostic (2.00e-2)" "unprognostic (1.07e-2)" "unprognostic (3.21e-2)" "unprognostic (2.43e-2)" "unprognostic (3.05e-3)" "unprognostic (1.16e-1)" "unprognostic (1.40e-1)" "validated prognostic unfavorable (1.89e-5)" "validated prognostic unfavorable (9.04e-4)" "unprognostic (3.89e-2)" "unprognostic (1.02e-1)" "unprognostic (6.00e-2)" "unprognostic (5.60e-2)" "unprognostic (2.28e-1)" "unprognostic (1.58e-1)" "unprognostic (9.45e-2)" "unprognostic (9.38e-2)" "unprognostic (2.46e-1)" "unprognostic (3.84e-2)" "unprognostic (2.52e-1)" "unprognostic (5.59e-2)" "unprognostic (1.30e-1)" "unprognostic (4.86e-1)" "unprognostic (1.20e-1)" "unprognostic (9.81e-2)" NIFK "hNIFK, MKI67IP, Nopp34" ENSG00000155438 "Nucleolar protein interacting with the FHA domain of MKI67" Q9BYG3 2 121726945-121736911 "Essential proteins, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 172.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015382, HPA035735, HPA035736, CAB075728, CAB075729" Supported Enhanced "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 54: Non-specific - Ribosome" "Cluster 55: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 17: Non-specific - RNA processing" 190 "Nucleoli, Nucleoli rim" "Mitotic chromosome" "CAB015382: , CAB075728: , CAB075729: , HPA035735: , HPA035736: " "unprognostic (3.00e-2)" "unprognostic (1.21e-1)" "unprognostic (4.17e-2)" "unprognostic (2.77e-2)" "unprognostic (3.83e-2)" "unprognostic (9.43e-2)" "unprognostic (3.70e-1)" "potential prognostic unfavorable (6.33e-5)" "unprognostic (5.68e-3)" "unprognostic (8.30e-3)" "unprognostic (4.05e-1)" "potential prognostic unfavorable (8.84e-5)" "potential prognostic unfavorable (1.52e-7)" "validated prognostic unfavorable (8.56e-5)" "validated prognostic unfavorable (8.39e-4)" "unprognostic (3.86e-2)" "unprognostic (4.52e-2)" "unprognostic (5.28e-2)" "unprognostic (7.52e-3)" "potential prognostic unfavorable (1.55e-4)" "unprognostic (3.18e-2)" "unprognostic (3.75e-2)" "unprognostic (4.76e-2)" "unprognostic (3.29e-2)" "unprognostic (1.38e-1)" "unprognostic (1.64e-1)" "unprognostic (2.38e-1)" "unprognostic (7.14e-2)" "unprognostic (2.25e-1)" NIM1K "MGC42105, NIM1" ENSG00000177453 "NIM1 serine/threonine protein kinase" Q8IY84 5 43192071-43280850 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 12.1;choroid plexus: 4.2;pituitary gland: 6.3;retina: 9.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 50.3;Astrocytes: 65.5;Bergmann glia: 70.7;Brain excitatory neurons: 50.2;Brain inhibitory neurons: 61.3;Choroid plexus epithelial cells: 85.0;Cone photoreceptor cells: 149.0;Ependymal cells: 79.2;Lactotrophs: 53.4;Oligodendrocyte progenitor cells: 73.0;Oligodendrocytes: 51.1;Retinal amacrine cells: 67.8;Retinal horizontal cells: 66.1;Rod photoreceptor cells: 62.6;Somatotrophs: 61.8;Thyrotrophs: 68.3" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in some" 11 "Glioblastoma Multiforme (TCGA): 14.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 1.7" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007695 Approved Cytosol NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 11: Neuronal - Sensory perception" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" Cytosol "HPA007695: " "unprognostic (1.63e-1)" "unprognostic (2.52e-2)" "unprognostic (1.05e-1)" "unprognostic (2.67e-1)" NIN ENSG00000100503 Ninein Q8N4C6 14 50719763-50831162 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 38.9" "Cell type enhanced" "Detected in many" "Müller glia: 339.6;Neutrophil progenitors: 451.7;Neutrophils: 1499.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 24.6" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005939, HPA070691" Approved Supported "Nucleoli,Nucleoli rim,Centrosome,Basal body" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 34: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 69 "Centrosome, Basal body" "Nucleoli, Nucleoli rim" "HPA005939: , HPA070691: " "unprognostic (1.50e-3)" "unprognostic (8.50e-2)" "unprognostic (2.87e-2)" "unprognostic (3.05e-2)" "unprognostic (4.74e-2)" "unprognostic (9.28e-2)" "unprognostic (6.15e-2)" "unprognostic (2.51e-3)" "unprognostic (6.05e-2)" "unprognostic (6.40e-3)" "potential prognostic favorable (1.93e-5)" "unprognostic (9.08e-3)" "unprognostic (2.32e-2)" "unprognostic (9.79e-2)" "unprognostic (2.10e-1)" "unprognostic (2.02e-2)" "unprognostic (1.29e-2)" "unprognostic (2.41e-1)" "unprognostic (1.80e-1)" "unprognostic (1.80e-3)" "unprognostic (1.32e-1)" "unprognostic (4.35e-2)" "unprognostic (2.26e-3)" "unprognostic (2.35e-1)" "unprognostic (1.40e-1)" "unprognostic (1.83e-1)" "unprognostic (1.17e-3)" "unprognostic (3.34e-1)" "unprognostic (2.38e-1)" "unprognostic (2.65e-2)" "unprognostic (1.84e-1)" NINJ1 NIN1 ENSG00000131669 "Ninjurin 1" Q92982 9 93121496-93134251 "Predicted membrane proteins" "Angiogenesis, Cell adhesion, Cytolysis, Inflammatory response" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 270.8" "Cell type enhanced" "Detected in many" "cDC: 244.0;Hofbauer cells: 1040.5;Kupffer cells: 273.7;Macrophages: 193.8;monocytes: 279.3;Neutrophils: 335.3" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 102.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1675.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 1675.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045063 Uncertain "Intracellular and membrane" "Cell adhesion" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 15: Bone marrow - Innate immune response" "Cluster 44: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 16 "HPA045063: " "unprognostic (3.33e-2)" "unprognostic (1.66e-2)" "unprognostic (1.21e-1)" "unprognostic (2.86e-2)" "unprognostic (9.20e-2)" "unprognostic (1.07e-1)" "unprognostic (2.23e-2)" "unprognostic (1.94e-1)" "unprognostic (1.38e-2)" "unprognostic (3.23e-1)" "unprognostic (6.09e-2)" "unprognostic (3.18e-1)" "unprognostic (4.93e-2)" "unprognostic (2.51e-3)" "unprognostic (2.37e-1)" "unprognostic (3.78e-3)" "unprognostic (7.35e-2)" "unprognostic (2.09e-1)" "unprognostic (5.89e-2)" "unprognostic (2.88e-1)" "unprognostic (2.16e-1)" "unprognostic (2.87e-2)" "unprognostic (5.24e-2)" "unprognostic (3.45e-2)" "unprognostic (1.29e-2)" "unprognostic (1.10e-1)" "unprognostic (1.44e-1)" "unprognostic (1.89e-1)" "unprognostic (8.81e-3)" "potential prognostic favorable (1.07e-5)" "unprognostic (2.00e-2)" NINJ2 ENSG00000171840 "Ninjurin 2" Q9NZG7 12 564296-663589 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 48.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 126.7;Fibro-adipogenic progenitors: 64.8;Hofbauer cells: 54.7;Kupffer cells: 63.5;Megakaryocytes: 123.6;Neutrophil progenitors: 56.8;Neutrophils: 101.8;Oligodendrocytes: 173.4;Sertoli cells: 51.3" "Group enriched" "Detected in many" 4 "committed oligodendrocyte precursor: 69.6;oligodendrocyte: 222.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 27.0;lymphoma: 16.2" "Lung - Alveolar cells type 1, Prostate - Fibroblasts, Spleen - Neutrophils_2, Testis - Sertoli cells" "Low region specificity" "Detected in all" "HPA058980, HPA067226" Approved "Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 59: Leukemia - T-cell receptor" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 63 "Endoplasmic reticulum" "Plasma membrane" "HPA058980: , HPA067226: " "unprognostic (1.30e-1)" "unprognostic (5.71e-2)" "unprognostic (2.73e-1)" "unprognostic (1.55e-1)" "unprognostic (2.20e-2)" "unprognostic (1.27e-1)" "unprognostic (5.28e-2)" "unprognostic (1.08e-1)" "unprognostic (2.75e-3)" "unprognostic (1.52e-1)" "unprognostic (1.66e-2)" "unprognostic (3.78e-1)" "unprognostic (9.75e-2)" "unprognostic (6.28e-3)" "unprognostic (1.94e-2)" "potential prognostic favorable (3.44e-6)" "unprognostic (2.37e-1)" "unprognostic (2.44e-2)" "unprognostic (8.09e-2)" "unprognostic (1.88e-3)" "unprognostic (2.50e-1)" "unprognostic (1.79e-2)" "unprognostic (1.19e-3)" "unprognostic (1.14e-1)" "unprognostic (4.53e-3)" "unprognostic (1.62e-1)" "unprognostic (6.98e-3)" "unprognostic (2.08e-1)" "unprognostic (4.58e-3)" "unprognostic (1.63e-3)" "unprognostic (2.73e-1)" NINL "KIAA0980, NLP" ENSG00000101004 "Ninein like" Q9Y2I6 20 25451594-25585531 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 222.4;Loop of henle epithelial cells: 199.2;Proximal tubule cells: 296.5;Renal collecting duct intercalated cells: 208.7;Renal connecting tubule cells: 210.8;Salivary duct cells: 173.7;Sertoli cells: 191.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Skeletal muscle - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA000686 Uncertain Approved "Nucleoplasm,Vesicles,Microtubules,Cytokinetic bridge,Primary cilium,Cytosol" Yes No "Cluster 64: Non-specific - Transcription" "Cluster 44: Non-specific - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 99 "Vesicles, Primary cilium" "Nucleoplasm, Microtubules, Cytokinetic bridge, Cytosol" "HPA000686: " "unprognostic (1.23e-1)" "unprognostic (5.94e-2)" "unprognostic (5.20e-2)" "unprognostic (1.14e-1)" "unprognostic (7.23e-2)" "unprognostic (6.14e-2)" "unprognostic (8.14e-2)" "unprognostic (2.34e-2)" "unprognostic (4.15e-2)" "unprognostic (1.27e-3)" "unprognostic (5.32e-2)" "unprognostic (1.18e-1)" "potential prognostic favorable (4.31e-5)" "unprognostic (2.68e-1)" "unprognostic (3.52e-2)" "unprognostic (3.13e-2)" "unprognostic (1.46e-1)" "unprognostic (3.48e-1)" "unprognostic (4.67e-2)" "unprognostic (1.19e-1)" "unprognostic (1.21e-2)" "unprognostic (1.56e-3)" "unprognostic (1.43e-2)" "unprognostic (1.85e-1)" "unprognostic (2.77e-2)" "potential prognostic favorable (9.13e-4)" "unprognostic (2.88e-1)" "unprognostic (6.22e-3)" "unprognostic (1.27e-1)" "unprognostic (2.96e-1)" "unprognostic (3.40e-2)" NIP7 "CGI-37, FLJ10296, HSPC031, KD93" ENSG00000132603 "Nucleolar pre-rRNA processing protein NIP7" Q9Y221 16 69337996-69343106 "Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 77.7;Gastric progenitor cells: 71.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040856, HPA059850" Supported Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 21: Non-specific - Metabolism" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 17: Non-specific - RNA processing" 17 Nucleoli "Nucleoplasm, Cytosol" "HPA040856: , HPA059850: " "unprognostic (5.21e-2)" "unprognostic (1.37e-1)" "unprognostic (1.02e-1)" "unprognostic (9.49e-3)" "unprognostic (2.51e-1)" "unprognostic (9.00e-2)" "unprognostic (6.39e-3)" "unprognostic (4.86e-2)" "potential prognostic unfavorable (3.12e-4)" "unprognostic (2.29e-1)" "unprognostic (3.95e-2)" "unprognostic (1.49e-1)" "unprognostic (4.98e-1)" "potential prognostic unfavorable (9.87e-4)" "unprognostic (1.36e-2)" "potential prognostic unfavorable (3.89e-4)" "unprognostic (6.01e-3)" "unprognostic (5.19e-2)" "unprognostic (9.63e-2)" "unprognostic (2.81e-2)" "unprognostic (1.40e-1)" "potential prognostic unfavorable (1.02e-4)" "unprognostic (9.20e-2)" "unprognostic (1.35e-2)" "unprognostic (2.55e-2)" "unprognostic (8.78e-2)" "unprognostic (3.10e-2)" "unprognostic (2.93e-1)" "unprognostic (9.12e-2)" "unprognostic (1.60e-1)" "unprognostic (3.51e-2)" NIPA1 "MGC35570, SLC57A1, SPG6" ENSG00000170113 "NIPA magnesium transporter 1" Q7RTP0 15 22773063-22829789 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "brain: 56.5" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 39.3;Brain inhibitory neurons: 43.9;Choroid plexus epithelial cells: 31.4;Distal convoluted tubule cells: 52.1;Loop of henle epithelial cells: 43.3;Oligodendrocyte progenitor cells: 24.3;Oligodendrocytes: 70.2;Other brain neurons: 41.8;Papillary tip epithelial cells: 23.3;Podocytes: 24.3;Proximal tubule cells: 29.0;Renal collecting duct intercalated cells: 50.6;Renal collecting duct principal cells: 25.9;Renal connecting tubule cells: 42.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 3.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023269 Uncertain NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 45: Non-specific - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 102: Non-specific - Mixed function" 3 "HPA023269: " "unprognostic (1.78e-1)" "unprognostic (2.00e-2)" "unprognostic (8.31e-2)" "unprognostic (2.73e-1)" "unprognostic (1.35e-1)" "unprognostic (6.83e-3)" "unprognostic (2.63e-1)" "unprognostic (2.35e-1)" "unprognostic (1.04e-1)" "unprognostic (3.49e-2)" "potential prognostic favorable (5.51e-4)" "unprognostic (1.12e-1)" "unprognostic (3.51e-1)" "unprognostic (1.84e-2)" "potential prognostic unfavorable (8.82e-4)" "unprognostic (1.17e-2)" "unprognostic (2.33e-1)" "unprognostic (2.28e-1)" "unprognostic (1.74e-2)" "unprognostic (9.31e-2)" "unprognostic (3.11e-1)" "unprognostic (8.30e-2)" "unprognostic (7.80e-2)" "unprognostic (7.96e-2)" "unprognostic (1.74e-1)" "unprognostic (2.73e-2)" "unprognostic (2.06e-1)" "unprognostic (4.62e-1)" "unprognostic (1.31e-1)" "unprognostic (8.34e-3)" "unprognostic (1.97e-1)" NIPA2 SLC57A2 ENSG00000140157 "NIPA magnesium transporter 2" Q8N8Q9 15 22838644-22869362 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 31.6;Microglia: 46.7;Papillary tip epithelial cells: 34.7;Renal collecting duct intercalated cells: 33.7;Renal connecting tubule cells: 36.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067160, HPA071342" Approved Approved "Golgi apparatus" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 21: Non-specific - Metabolism" "Cluster 58: Non-specific - Nuclear processes" "Cluster 102: Non-specific - Mixed function" 2 "Golgi apparatus" "HPA067160: , HPA071342: " "unprognostic (3.69e-1)" "potential prognostic unfavorable (8.09e-4)" "unprognostic (2.21e-1)" "unprognostic (7.07e-2)" "unprognostic (1.55e-2)" "unprognostic (1.36e-1)" "unprognostic (3.13e-1)" "unprognostic (2.32e-1)" "unprognostic (1.91e-1)" "unprognostic (2.78e-3)" "potential prognostic favorable (1.89e-4)" "unprognostic (4.58e-1)" "unprognostic (3.48e-1)" "unprognostic (2.31e-2)" "unprognostic (1.19e-3)" "unprognostic (6.27e-3)" "unprognostic (9.82e-3)" "unprognostic (6.88e-2)" "unprognostic (8.95e-2)" "unprognostic (1.39e-1)" "unprognostic (2.46e-3)" "unprognostic (1.41e-2)" "unprognostic (3.95e-2)" "unprognostic (3.23e-1)" "unprognostic (1.82e-1)" "unprognostic (8.04e-2)" "unprognostic (1.12e-1)" "unprognostic (5.10e-2)" "unprognostic (2.96e-1)" "unprognostic (2.07e-2)" "unprognostic (3.52e-1)" NIPAL1 "DKFZp686A06115, NPAL1, SLC57A3" ENSG00000163293 "NIPA like domain containing 1" Q6NVV3 4 47914142-48040173 "Predicted membrane proteins" "Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 20.5;liver: 15.1;skin 1: 24.3" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 263.9;Esophageal suprabasal cells: 144.5;Papillary tip epithelial cells: 102.9;Renal collecting duct principal cells: 118.8;Rod photoreceptor cells: 259.5;Suprabasal keratinocytes: 107.4;Urothelial cells: 198.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Minor Salivary Gland - Minor salivary gland basal cells, Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA036765 Uncertain Approved "Golgi apparatus" NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 69: Urothelial cells - Basic cellular functions" 18 "Golgi apparatus" "HPA036765: " "unprognostic (6.49e-3)" "unprognostic (2.85e-1)" "unprognostic (3.14e-1)" "unprognostic (2.84e-2)" "unprognostic (1.80e-2)" "unprognostic (7.51e-3)" "unprognostic (5.18e-1)" "unprognostic (1.96e-1)" "unprognostic (1.16e-1)" "unprognostic (2.53e-1)" "potential prognostic unfavorable (4.37e-4)" "unprognostic (2.56e-2)" "unprognostic (1.89e-1)" "unprognostic (3.39e-1)" "unprognostic (2.84e-2)" "unprognostic (1.36e-1)" "unprognostic (1.27e-3)" "unprognostic (6.64e-2)" "unprognostic (6.66e-2)" "unprognostic (6.02e-3)" "unprognostic (8.36e-3)" "unprognostic (1.27e-1)" "unprognostic (3.08e-1)" "unprognostic (3.92e-1)" "unprognostic (1.53e-1)" NIPAL2 "FLJ13955, NPAL2, SLC57A4" ENSG00000104361 "NIPA like domain containing 2" Q9H841 8 98189826-98294393 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 221.0;Prostatic glandular cells: 163.9;Somatotrophs: 199.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Pituitary gland - Somatotropes, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071759 Uncertain NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 58: Skin - Keratinization" "Cluster 53: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" "HPA071759: " "unprognostic (5.12e-2)" "unprognostic (1.99e-3)" "unprognostic (6.48e-2)" "unprognostic (2.42e-2)" "unprognostic (2.50e-1)" "unprognostic (8.29e-2)" "unprognostic (1.12e-2)" "unprognostic (1.13e-3)" "unprognostic (1.62e-1)" "unprognostic (2.93e-3)" "unprognostic (2.59e-2)" "unprognostic (3.24e-2)" "unprognostic (1.31e-1)" "unprognostic (2.77e-1)" "unprognostic (6.14e-2)" "unprognostic (1.18e-1)" "unprognostic (2.36e-1)" "unprognostic (1.68e-2)" "unprognostic (5.80e-3)" "unprognostic (1.06e-1)" "unprognostic (1.09e-2)" "unprognostic (1.62e-1)" "unprognostic (1.26e-2)" "unprognostic (8.09e-2)" "unprognostic (1.14e-1)" "unprognostic (2.04e-2)" "unprognostic (5.56e-2)" "unprognostic (2.34e-1)" "unprognostic (6.81e-2)" "unprognostic (3.75e-1)" "unprognostic (1.46e-2)" NIPAL3 "DJ462O23.2, NPAL3, SLC57A5" ENSG00000001461 "NIPA like domain containing 3" Q6P499 1 24415802-24472976 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 59.6" "Cell type enriched" "Detected in many" 4 "Prostatic glandular cells: 611.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal cortex cells, Colon - Smooth muscle cells, Prostate - Prostate glandular cells, Spleen - B-cells (Spleen), Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039978 Approved Approved Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 13 Nucleoplasm "HPA039978: " "unprognostic (2.44e-1)" "unprognostic (1.82e-1)" "unprognostic (6.19e-2)" "unprognostic (1.01e-3)" "unprognostic (6.58e-2)" "unprognostic (9.66e-2)" "unprognostic (1.26e-1)" "unprognostic (2.04e-2)" "unprognostic (8.81e-2)" "unprognostic (4.88e-3)" "potential prognostic favorable (3.66e-9)" "unprognostic (3.56e-3)" "unprognostic (1.28e-2)" "potential prognostic unfavorable (9.39e-5)" "unprognostic (1.76e-1)" "unprognostic (7.08e-2)" "unprognostic (1.91e-1)" "unprognostic (1.82e-1)" "unprognostic (2.77e-2)" "unprognostic (1.11e-1)" "unprognostic (2.34e-2)" "unprognostic (8.06e-2)" "unprognostic (3.56e-2)" "unprognostic (2.08e-1)" "unprognostic (1.16e-1)" "unprognostic (1.29e-2)" "unprognostic (2.77e-1)" "unprognostic (4.47e-2)" "unprognostic (1.77e-1)" "unprognostic (2.59e-2)" "unprognostic (7.21e-2)" NIPAL4 "ICHYN, SLC57A6" ENSG00000172548 "NIPA like domain containing 4" Q0D2K0 5 157460213-157474722 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" Receptor "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.7;skin 1: 63.0" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 29.0;Esophageal apical cells: 8.2;Esophageal basal cells: 19.6;Esophageal suprabasal cells: 27.7;Myosatellite cells: 13.3;Ocular epithelial cells: 9.7;Oligodendrocytes: 18.4;Prostatic hillock cells: 15.2;Suprabasal keratinocytes: 47.8;Urothelial cells: 29.8" "Cell type enriched" "Detected in some" 5 "oligodendrocyte: 30.2" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 20.5;Head and Neck Squamous Cell Carcinoma (TCGA): 31.8" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 25 "memory B-cell: 1.6;naive B-cell: 4.9" "Lineage enriched" "Detected in single" 37 "B-cells: 4.9" "Cancer enhanced" "Detected in many" "Bladder cancer: 10.5;head and neck cancer: 9.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038259 Approved NA NA "Cluster 34: B-cells - Unknown function" "Cluster 9: Skin - Hair follicle development" "Cluster 30: White matter - Myelination" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 26: Keratinocytes - Keratinization" 15 "HPA038259: " "unprognostic (5.59e-2)" "unprognostic (3.68e-2)" "unprognostic (9.27e-2)" "unprognostic (8.44e-2)" "unprognostic (2.72e-1)" "unprognostic (4.26e-2)" "unprognostic (8.14e-3)" "unprognostic (2.34e-2)" "unprognostic (4.28e-2)" "unprognostic (1.84e-2)" "unprognostic (2.65e-1)" "unprognostic (5.61e-2)" NIPBL "DKFZp434L1319, FLJ11203, FLJ12597, FLJ13354, FLJ13648, IDN3, Scc2" ENSG00000164190 "NIPBL cohesin loading factor" Q6KC79 5 36876769-37066413 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation" "Activator, Developmental protein" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 1263.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040834, HPA058239" Approved Supported Nucleoplasm,Vesicles,Cytosol No No "Cluster 21: Neutrophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 29: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 37 Nucleoplasm "Vesicles, Cytosol" "HPA040834: , HPA058239: " "unprognostic (1.08e-1)" "unprognostic (4.46e-2)" "unprognostic (3.44e-1)" "unprognostic (1.99e-3)" "unprognostic (1.76e-1)" "unprognostic (3.26e-1)" "unprognostic (7.37e-2)" "unprognostic (1.18e-1)" "unprognostic (8.10e-2)" "unprognostic (8.94e-3)" "validated prognostic favorable (1.85e-5)" "validated prognostic favorable (1.67e-4)" "unprognostic (6.71e-2)" "unprognostic (2.03e-2)" "unprognostic (4.73e-1)" "unprognostic (3.20e-1)" "unprognostic (1.34e-1)" "unprognostic (1.15e-1)" "unprognostic (1.82e-1)" "unprognostic (9.61e-2)" "unprognostic (2.05e-1)" "unprognostic (5.88e-3)" "unprognostic (1.51e-3)" "unprognostic (1.63e-1)" "unprognostic (7.27e-3)" "unprognostic (2.06e-1)" "unprognostic (4.99e-2)" "unprognostic (1.71e-1)" "unprognostic (3.03e-1)" "unprognostic (9.61e-3)" "unprognostic (1.80e-1)" NIPSNAP1 ENSG00000184117 "Nipsnap homolog 1" Q9BPW8 22 29554808-29581327 "Plasma proteins, Predicted intracellular proteins" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 272.7" "Cell type enhanced" "Detected in many" "Hepatocytes: 45.3;Proximal tubule cells: 49.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Liver - Hepatocytes, Skeletal muscle - Fibroblasts, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059227 Uncertain NA NA 15000 "Cluster 1: T-cells - Unknown function" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 1: Neurons - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 88: Proximal tubular cells - Transmembrane transport" 31 "HPA059227: " "unprognostic (2.87e-2)" "unprognostic (1.36e-1)" "unprognostic (1.52e-1)" "unprognostic (5.15e-2)" "unprognostic (1.28e-2)" "unprognostic (1.31e-2)" "unprognostic (1.88e-1)" "unprognostic (3.25e-1)" "unprognostic (4.66e-2)" "unprognostic (1.62e-2)" "potential prognostic favorable (2.02e-5)" "unprognostic (1.87e-1)" "potential prognostic favorable (2.30e-5)" "unprognostic (1.19e-1)" "unprognostic (1.77e-3)" "unprognostic (9.91e-2)" "unprognostic (9.68e-2)" "unprognostic (1.79e-2)" "unprognostic (2.02e-3)" "unprognostic (2.26e-2)" "unprognostic (6.30e-2)" "unprognostic (2.11e-2)" "unprognostic (1.24e-1)" "unprognostic (1.06e-1)" "unprognostic (1.49e-3)" "unprognostic (1.06e-1)" "unprognostic (7.50e-2)" "unprognostic (2.41e-1)" "unprognostic (1.29e-1)" "unprognostic (4.72e-2)" "unprognostic (5.04e-2)" NIPSNAP2 GBAS ENSG00000146729 "Nipsnap homolog 2" O75323 7 55951793-56000181 "Predicted intracellular proteins" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "heart muscle: 249.4;skeletal muscle: 604.5;tongue: 732.5" "Cell type enhanced" "Detected in all" "Myonuclei: 406.4;Parietal cells: 388.9" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 336.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063084 Enhanced Supported Mitochondria NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 21: Non-specific - Metabolism" "Cluster 67: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 37 Mitochondria "HPA063084: " "unprognostic (2.61e-2)" "unprognostic (6.66e-2)" "unprognostic (9.60e-3)" "unprognostic (9.99e-2)" "unprognostic (1.43e-2)" "unprognostic (1.27e-1)" "potential prognostic unfavorable (9.33e-4)" "unprognostic (8.92e-3)" "unprognostic (7.42e-2)" "unprognostic (6.17e-3)" "unprognostic (1.01e-1)" "potential prognostic favorable (3.38e-4)" "unprognostic (1.40e-2)" "unprognostic (5.27e-2)" "unprognostic (1.31e-1)" "unprognostic (2.44e-1)" "unprognostic (2.43e-1)" "unprognostic (4.31e-2)" "unprognostic (1.76e-1)" "unprognostic (1.17e-1)" "unprognostic (1.47e-2)" "unprognostic (1.59e-1)" "unprognostic (4.48e-2)" "unprognostic (2.55e-2)" "unprognostic (1.80e-1)" "unprognostic (3.08e-2)" "unprognostic (1.39e-1)" "unprognostic (7.30e-3)" "unprognostic (1.73e-1)" NIPSNAP3A "DKFZp564D177, FLJ13953, HSPC299, MGC14553, NIPSNAP4, TassC" ENSG00000136783 "Nipsnap homolog 3A" Q9UFN0 9 104747683-104760120 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 134.3;Megakaryocytes: 136.0;Oocytes: 119.7;Parietal cells: 125.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA042491 Approved NA NA 18000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 76: Non-specific - Metabolism" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 97: Non-specific - Cellular respiration" 46 "HPA042491: " "unprognostic (3.14e-1)" "unprognostic (4.10e-2)" "potential prognostic unfavorable (4.29e-4)" "unprognostic (1.74e-1)" "unprognostic (1.02e-1)" "unprognostic (1.88e-1)" "unprognostic (1.98e-1)" "unprognostic (1.66e-1)" "unprognostic (1.88e-1)" "unprognostic (7.34e-2)" "potential prognostic favorable (3.26e-6)" "unprognostic (2.01e-1)" "unprognostic (1.18e-2)" "unprognostic (1.08e-1)" "unprognostic (8.82e-2)" "unprognostic (3.28e-1)" "unprognostic (2.89e-2)" "unprognostic (2.22e-1)" "unprognostic (1.65e-1)" "unprognostic (2.49e-1)" "unprognostic (3.73e-3)" "unprognostic (1.94e-1)" "unprognostic (1.39e-1)" "unprognostic (8.99e-2)" "unprognostic (4.53e-2)" "unprognostic (1.09e-1)" "unprognostic (2.00e-2)" "unprognostic (9.49e-2)" "unprognostic (2.14e-1)" "unprognostic (3.10e-2)" "unprognostic (9.91e-2)" NIPSNAP3B "FLJ11275, NIPSNAP3, SNAP1" ENSG00000165028 "Nipsnap homolog 3B" Q9BS92 9 104764129-104777764 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 16.2;tongue: 18.2" "Cell type enhanced" "Detected in many" "Adipocytes: 70.7;Adrenal cortex cells: 119.4;Cardiomyocytes: 79.3;Hofbauer cells: 38.5;Microglia: 43.0;Myonuclei: 57.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.8" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in some" "Leukemia: 2.4" "Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Prostate - Fibroblasts, Skeletal muscle - Skeletal myocytes, Spleen - B-cells (Spleen)" HPA042491 Uncertain NA NA "Cluster 32: Basophils - Transcription" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 23: Choroid plexus - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 55: Myocytes - Oxidative muscle function" 10 "HPA042491: " "unprognostic (1.96e-1)" "unprognostic (3.43e-1)" "potential prognostic favorable (7.93e-4)" "unprognostic (2.95e-1)" "unprognostic (6.49e-2)" "unprognostic (9.61e-3)" "unprognostic (1.61e-1)" "unprognostic (5.49e-1)" "unprognostic (3.21e-1)" "unprognostic (4.27e-3)" "unprognostic (1.44e-1)" NISCH "I-1, IRAS, KIAA0975" ENSG00000010322 Nischarin Q9Y2I1 3 52455118-52493068 "Essential proteins, FDA approved drug targets, Predicted intracellular proteins" Apoptosis Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 276.3" "Cell type enhanced" "Detected in all" "Leydig cells: 169.2;Peritubular myoid cells: 367.2;Somatotrophs: 251.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pituitary gland - Somatotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023189 Approved Approved "Nucleoplasm,Vesicles,Microtubules,Cytokinetic bridge,Cytosol" Yes NA "Cluster 30: Non-specific - DNA binding" "Cluster 64: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 94: Gonadal somatic cells - Mixed function" 37 "Nucleoplasm, Cytosol" "Vesicles, Microtubules, Cytokinetic bridge" "HPA023189: " "unprognostic (4.33e-2)" "unprognostic (1.23e-1)" "unprognostic (3.27e-2)" "unprognostic (1.86e-1)" "unprognostic (1.39e-2)" "unprognostic (2.66e-2)" "unprognostic (1.20e-1)" "unprognostic (8.01e-3)" "unprognostic (2.67e-2)" "unprognostic (4.12e-2)" "unprognostic (8.33e-2)" "unprognostic (5.45e-3)" "unprognostic (1.13e-3)" "unprognostic (2.09e-2)" "unprognostic (3.04e-2)" "unprognostic (2.71e-3)" "unprognostic (2.18e-1)" "unprognostic (2.27e-1)" "unprognostic (1.00e-1)" "unprognostic (6.85e-2)" "unprognostic (1.06e-1)" "unprognostic (2.73e-3)" "unprognostic (3.15e-1)" "unprognostic (7.15e-2)" "unprognostic (9.83e-3)" "unprognostic (7.37e-3)" "unprognostic (9.17e-2)" "unprognostic (2.77e-1)" "unprognostic (1.75e-1)" "unprognostic (2.67e-1)" "unprognostic (5.26e-2)" NIT1 ENSG00000158793 "Nitrilase 1" Q86X76 1 161118086-161125445 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 153.8;Late spermatids: 141.7;Oocytes: 165.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006656, HPA006657" Approved Approved Mitochondria,Cytosol NA NA 77000 "Cluster 29: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 44: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" "Mitochondria, Cytosol" "HPA006656: , HPA006657: " "unprognostic (8.52e-3)" "unprognostic (7.23e-2)" "unprognostic (1.44e-1)" "unprognostic (5.60e-2)" "unprognostic (2.35e-1)" "unprognostic (1.88e-1)" "unprognostic (5.58e-3)" "unprognostic (2.73e-2)" "unprognostic (8.19e-3)" "unprognostic (8.00e-2)" "unprognostic (1.67e-1)" "unprognostic (1.64e-1)" "unprognostic (5.28e-2)" "unprognostic (2.59e-1)" "unprognostic (1.35e-3)" "unprognostic (3.74e-2)" "unprognostic (9.52e-2)" "unprognostic (2.06e-2)" "unprognostic (9.47e-2)" "unprognostic (1.12e-1)" "unprognostic (1.29e-1)" "unprognostic (2.93e-1)" "unprognostic (5.40e-2)" "unprognostic (1.66e-2)" "unprognostic (5.59e-2)" "unprognostic (7.09e-2)" "unprognostic (9.27e-2)" "unprognostic (2.11e-1)" "unprognostic (1.67e-1)" "unprognostic (1.61e-3)" "unprognostic (1.16e-1)" NIT2 ENSG00000114021 "Nitrilase family member 2" Q9NQR4 3 100334739-100361635 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 24.7" "Cell type enhanced" "Detected in many" "Gastric progenitor cells: 147.4;Hepatocytes: 220.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036999, HPA041289" Approved Supported Centrosome,Cytosol NA NA 2300000 "Cluster 11: T-cells - Unknown function" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 9: Non-specific - Receptor signaling" "Cluster 63: Non-specific - Protein processing" "Cluster 97: Non-specific - Cellular respiration" 1 Cytosol Centrosome "HPA036999: , HPA041289: " "unprognostic (2.16e-2)" "unprognostic (1.59e-3)" "unprognostic (3.06e-2)" "unprognostic (2.71e-1)" "unprognostic (2.34e-1)" "unprognostic (1.29e-1)" "unprognostic (1.04e-1)" "unprognostic (2.01e-1)" "unprognostic (3.24e-1)" "unprognostic (1.87e-3)" "unprognostic (1.02e-3)" "unprognostic (3.56e-1)" "unprognostic (1.39e-3)" "unprognostic (2.68e-2)" "unprognostic (3.99e-3)" "unprognostic (9.13e-3)" "unprognostic (5.68e-2)" "unprognostic (5.53e-2)" "unprognostic (8.97e-2)" "unprognostic (3.40e-1)" "unprognostic (1.02e-3)" "unprognostic (3.39e-1)" "unprognostic (1.50e-1)" "unprognostic (1.73e-1)" "unprognostic (8.23e-3)" "unprognostic (9.87e-2)" "unprognostic (4.74e-1)" "unprognostic (1.86e-1)" "unprognostic (1.77e-1)" "unprognostic (8.03e-3)" "unprognostic (2.37e-1)" NKAIN1 "FAM77C, FLJ12650" ENSG00000084628 "Sodium/potassium transporting ATPase interacting 1" Q4KMZ8 1 31179745-31239887 "Predicted membrane proteins, Transporters" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 6 "adrenal gland: 22.0;brain: 28.4;skeletal muscle: 18.2;tongue: 11.1" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 44.4;Adrenal medulla cells: 63.8;Brain excitatory neurons: 28.8;Epididymal efferent duct absorptive cells: 29.3;Myonuclei: 31.8;Oligodendrocytes: 39.3;Other brain neurons: 27.2;Retinal ganglion cells: 27.0" "Cell type enhanced" "Detected in many" "lower rhombic lip: 59.0" "Group enriched" "Detected in many" 5 "Breast Invasive Carcinoma (TCGA): 28.0;Glioblastoma Multiforme (TCGA): 8.1;Prostate Adenocarcinoma (TCGA): 14.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "breast cancer: 9.5;Neuroblastoma: 29.5" "Adrenal gland - Adrenal cortex cells, Colon - Colon enteroendocrine cells, Prostate - Prostate glandular cells, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006873 Uncertain NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" "HPA006873: " "unprognostic (2.07e-2)" "unprognostic (1.54e-2)" "unprognostic (9.72e-2)" "potential prognostic favorable (2.78e-4)" "unprognostic (4.87e-3)" "unprognostic (2.91e-3)" "unprognostic (1.34e-1)" "unprognostic (6.79e-2)" "unprognostic (4.02e-2)" "unprognostic (2.11e-1)" "unprognostic (2.29e-2)" "unprognostic (2.70e-2)" NKAIN2 "FAM77B, TCBA1" ENSG00000188580 "Sodium/potassium transporting ATPase interacting 2" Q5VXU1 6 123803865-124825640 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 14 "brain: 84.1" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 2467.6;Brain inhibitory neurons: 1070.5;Corticotrophs: 2378.6;Hematopoietic stem cells: 1909.4;Megakaryocyte-Erythroid progenitors: 713.5;Myonuclei: 1355.4;Oligodendrocytes: 2965.9;Other brain neurons: 828.6;Pituicytes/FSCs: 1141.4;Retinal horizontal cells: 1274.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 3.6;Lung Squamous Cell Carcinoma (TCGA): 5.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 19 "basophil: 1.9" "Lineage enriched" "Detected in single" 19 "granulocytes: 1.9" "Cancer enhanced" "Detected in some" "lung cancer: 4.2;thyroid cancer: 7.1" "Pituitary gland - Undifferentiated cells (Pituitary gland), Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045860 Approved Cytosol NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 80: Oligodendrocytes - Myelination" Cytosol "HPA045860: " "unprognostic (4.57e-1)" "unprognostic (6.13e-2)" "unprognostic (1.39e-1)" "unprognostic (1.35e-1)" "unprognostic (5.47e-2)" "unprognostic (8.43e-3)" "unprognostic (1.98e-3)" "unprognostic (6.24e-2)" "unprognostic (3.35e-3)" "unprognostic (5.59e-2)" "unprognostic (1.58e-1)" NKAIN3 "FAM77D, FLJ39630, NKAIN3-IT1" ENSG00000185942 "Sodium/potassium transporting ATPase interacting 3" Q8N8D7 8 62248591-63014000 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 10.0" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 571.8;Astrocytes: 2221.5;Brain excitatory neurons: 268.8;Brain inhibitory neurons: 247.5;Decidual stromal cells: 227.5;Ependymal cells: 242.0;Oligodendrocyte progenitor cells: 877.5;Other brain neurons: 394.3;Schwann cells: 603.5" "Cell type enhanced" "Detected in all" "astrocyte: 2147.3;hippocampal CA4: 1732.6" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 6.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Smooth muscle cells, Colon - Enteric glia cells, Liver - Hepatocytes, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA018833 Enhanced NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 28: Astrocytes - Homeostasis & neuron support" "HPA018833: " "unprognostic (7.39e-2)" "unprognostic (1.41e-1)" "unprognostic (1.13e-2)" "potential prognostic favorable (1.35e-4)" "unprognostic (7.28e-3)" "unprognostic (9.50e-2)" "unprognostic (2.46e-1)" NKAIN4 "bA261N11.2, C20orf58, FAM77A" ENSG00000101198 "Sodium/potassium transporting ATPase interacting 4" Q8IVV8 20 63240784-63272694 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 24 "brain: 88.5;kidney: 53.5" "Cell type enhanced" "Detected in many" "Astrocytes: 115.6;Bergmann glia: 84.9;Epididymal efferent duct absorptive cells: 42.6;Migrating cytotrophoblasts: 22.2;Müller glia: 86.1;Oligodendrocyte progenitor cells: 120.2;Proximal tubule cells: 45.9" "Group enriched" "Detected in many" 5 "astrocyte: 134.3;Bergmann glia: 93.8;committed oligodendrocyte precursor: 34.7;oligodendrocyte precursor cell: 117.7" "Cancer enriched" "Detected in many" 7 "Glioblastoma Multiforme (TCGA): 150.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 27.2;Uterine cancer: 16.5" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA029876 Approved NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 1 "HPA029876: " "unprognostic (1.13e-1)" "unprognostic (5.14e-3)" "unprognostic (5.95e-2)" "unprognostic (5.11e-2)" "potential prognostic favorable (6.19e-4)" "unprognostic (7.08e-2)" "potential prognostic unfavorable (1.53e-4)" "unprognostic (2.29e-1)" "unprognostic (4.05e-3)" "unprognostic (2.07e-1)" "unprognostic (2.29e-1)" "unprognostic (2.67e-1)" "unprognostic (2.10e-1)" "unprognostic (1.18e-1)" "unprognostic (1.07e-2)" "unprognostic (1.91e-1)" "potential prognostic unfavorable (3.92e-5)" "unprognostic (6.77e-2)" "unprognostic (7.94e-2)" "unprognostic (7.73e-3)" NKAP FLJ22626 ENSG00000101882 "NFKB activating protein" Q8N5F7 X 119920672-119943751 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Notch signaling pathway, Transcription, Transcription regulation" Repressor "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 188.6;Oocytes: 165.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000916 Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 58 Nucleoplasm Cytosol "HPA000916: " "unprognostic (8.66e-2)" "potential prognostic unfavorable (9.37e-6)" "unprognostic (2.43e-2)" "unprognostic (3.17e-2)" "unprognostic (1.63e-1)" "unprognostic (2.37e-1)" "unprognostic (2.47e-1)" "unprognostic (9.64e-2)" "unprognostic (1.54e-3)" "unprognostic (1.17e-2)" "unprognostic (4.97e-3)" "unprognostic (1.44e-1)" "unprognostic (2.08e-3)" "validated prognostic unfavorable (5.18e-5)" "validated prognostic unfavorable (2.55e-4)" "unprognostic (2.72e-1)" "unprognostic (4.71e-3)" "unprognostic (2.16e-2)" "unprognostic (7.30e-2)" "unprognostic (1.92e-1)" "unprognostic (1.05e-1)" "unprognostic (2.66e-1)" "unprognostic (2.32e-3)" "unprognostic (5.46e-2)" "unprognostic (1.57e-1)" "unprognostic (1.91e-1)" "unprognostic (6.63e-2)" "unprognostic (2.24e-1)" "unprognostic (4.29e-2)" "unprognostic (7.35e-2)" "unprognostic (5.05e-2)" NKAPD1 "C11orf57, FLJ10726" ENSG00000150776 "NKAP domain containing 1" Q6ZUT1 11 112074086-112085150 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039493, HPA039892" Approved Approved Cytosol NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 55: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 53 Cytosol "HPA039493: , HPA039892: " "unprognostic (6.09e-3)" "unprognostic (2.19e-3)" "unprognostic (2.62e-2)" "unprognostic (2.28e-1)" "unprognostic (1.88e-2)" "unprognostic (4.93e-2)" "unprognostic (5.43e-2)" "unprognostic (4.38e-2)" "unprognostic (1.90e-2)" "potential prognostic favorable (5.30e-7)" "unprognostic (1.61e-3)" "unprognostic (5.43e-3)" "potential prognostic unfavorable (1.35e-4)" "unprognostic (4.39e-2)" "unprognostic (7.98e-3)" "unprognostic (2.29e-1)" "unprognostic (6.60e-2)" "unprognostic (2.88e-1)" "unprognostic (1.06e-3)" "unprognostic (1.21e-3)" "unprognostic (8.32e-3)" "unprognostic (5.74e-3)" "unprognostic (1.07e-3)" "unprognostic (2.95e-1)" "unprognostic (4.38e-2)" "unprognostic (9.16e-2)" "unprognostic (1.78e-1)" "unprognostic (1.78e-1)" "unprognostic (3.08e-3)" NKAPL "bA424I5.1, C6orf194" ENSG00000189134 "NFKB activating protein like" Q5M9Q1 6 28259297-28260958 "Predicted intracellular proteins" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 11.7;testis: 30.4" "Group enriched" "Detected in many" 4 "Early spermatids: 295.2;Late primary spermatocytes: 753.8" "Cell type enhanced" "Detected in many" "lower rhombic lip: 32.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Prostate - Smooth muscle cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA071697 Uncertain "Nucleoplasm,Golgi apparatus" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 47: Testis - Mixed function" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 8 "Golgi apparatus" Nucleoplasm "HPA071697: " "unprognostic (7.33e-2)" "unprognostic (9.38e-2)" NKD1 ENSG00000140807 "NKD inhibitor of WNT signaling pathway 1" Q969G9 16 50548396-50649249 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 14.7" "Cell type enriched" "Detected in many" 4 "Podocytes: 438.0" "Cell type enhanced" "Detected in many" "endothelial cell: 182.5;fibroblast: 337.9" "Cancer enhanced" "Detected in many" "Rectum Adenocarcinoma (TCGA): 13.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 28.1;colorectal cancer: 19.6;Gastric cancer: 21.0" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Testis - Early spermatids, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041352, HPA049413" Uncertain Approved "Nucleoli fibrillar center" NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 57: Podocytes - Glomerular filtration" 11 "Nucleoli fibrillar center" "HPA041352: , HPA049413: " "unprognostic (1.05e-2)" "unprognostic (1.67e-1)" "unprognostic (1.18e-3)" "unprognostic (3.32e-1)" "unprognostic (4.14e-3)" "unprognostic (5.91e-3)" "potential prognostic favorable (2.81e-5)" "unprognostic (3.99e-1)" "unprognostic (1.55e-1)" "potential prognostic favorable (7.75e-4)" "unprognostic (4.95e-2)" "unprognostic (9.13e-3)" "unprognostic (1.35e-1)" "unprognostic (2.92e-2)" "potential prognostic unfavorable (6.16e-4)" "unprognostic (8.24e-2)" "unprognostic (1.54e-1)" "unprognostic (3.34e-1)" "unprognostic (4.73e-1)" "unprognostic (1.01e-2)" "unprognostic (2.11e-3)" "unprognostic (3.23e-1)" "unprognostic (8.60e-2)" "unprognostic (5.68e-3)" NKD2 Naked2 ENSG00000145506 "NKD inhibitor of WNT signaling pathway 2" Q969F2 5 1008802-1038943 "Predicted intracellular proteins" "Exocytosis, Transport, Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 40.8" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 1.2;Brain inhibitory neurons: 1.0;Choroid plexus epithelial cells: 1.8;Ependymal cells: 2.1;Fibroblasts: 3.2;Proximal tubule cells: 2.3" "Cell type enhanced" "Detected in many" "endothelial cell: 18.6;fibroblast: 42.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 15.0" "Colon - Enteric glia cells, Spleen - Fibroblasts_1, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA049463 Uncertain NA NA "Cluster 5: Spleen - Immune response" "Cluster 51: Neurons - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 104: Brain endothelial cells - Blood brain barrier" 14 "HPA049463: " "unprognostic (5.34e-2)" "unprognostic (8.43e-2)" "unprognostic (3.65e-2)" "unprognostic (1.31e-2)" "unprognostic (1.60e-1)" "unprognostic (2.12e-1)" "unprognostic (7.93e-2)" "unprognostic (5.13e-2)" "unprognostic (2.42e-1)" "potential prognostic unfavorable (7.65e-4)" "unprognostic (2.11e-2)" "potential prognostic favorable (4.37e-5)" "unprognostic (1.52e-1)" "unprognostic (6.00e-2)" "unprognostic (1.46e-2)" "unprognostic (2.51e-2)" "unprognostic (3.16e-1)" "unprognostic (5.98e-2)" "unprognostic (1.24e-1)" "unprognostic (1.67e-1)" "unprognostic (3.21e-1)" "unprognostic (3.14e-1)" "unprognostic (3.07e-1)" NKG7 "GIG1, GMP-17" ENSG00000105374 "Natural killer cell granule protein 7" Q16617 19 51371606-51372701 "Predicted intracellular proteins, Predicted membrane proteins" "Cytolysis, Inflammatory response" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "bone marrow: 568.3;lymphoid tissue: 161.0" "Cell type enhanced" "Detected in some" "Monocyte progenitors: 233.4;Neutrophil progenitors: 376.1;NK-cells: 2043.7;T-cells: 527.2" "Cell type enriched" "Detected in some" 234 "leukocyte: 512.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "gdT-cell: 6845.3;MAIT T-cell: 2877.8;memory CD8 T-cell: 4296.3;naive CD8 T-cell: 3123.7;NK-cell: 4809.3" "Group enriched" "Detected in all" 44 "NK-cells: 4809.3;T-cells: 6845.3" "Group enriched" "Detected in some" 30 "Leukemia: 67.0;lymphoma: 75.8" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Minor Salivary Gland - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA071454 Approved Vesicles NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 39 Vesicles "HPA071454: " "unprognostic (1.86e-2)" "unprognostic (2.90e-3)" "unprognostic (3.78e-1)" "unprognostic (2.40e-2)" "unprognostic (6.88e-2)" "unprognostic (5.43e-2)" "potential prognostic unfavorable (2.04e-4)" "unprognostic (2.00e-1)" "unprognostic (2.01e-3)" "unprognostic (6.98e-2)" "unprognostic (1.60e-1)" "unprognostic (1.46e-1)" "unprognostic (3.28e-3)" "unprognostic (7.98e-3)" "unprognostic (2.00e-2)" "unprognostic (4.26e-1)" "unprognostic (2.40e-1)" "unprognostic (3.59e-1)" "unprognostic (1.76e-1)" "unprognostic (2.34e-3)" "unprognostic (3.86e-2)" "unprognostic (1.77e-1)" "unprognostic (5.34e-2)" "unprognostic (1.94e-1)" "unprognostic (6.76e-3)" "unprognostic (3.02e-1)" "unprognostic (1.05e-3)" "unprognostic (7.77e-3)" "unprognostic (2.19e-1)" "unprognostic (8.00e-3)" "unprognostic (1.30e-1)" NKIRAS1 "kappaB-Ras1, KBRAS1" ENSG00000197885 "NFKB inhibitor interacting Ras like 1" Q9NYS0 3 23889951-23946591 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 115.9;Epicardial cells: 204.7;Oocytes: 156.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077387 Approved Approved "Endoplasmic reticulum,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "Endoplasmic reticulum, Cytosol" "HPA077387: " "unprognostic (2.32e-1)" "unprognostic (9.01e-3)" "unprognostic (8.69e-2)" "unprognostic (1.60e-1)" "unprognostic (1.12e-1)" "unprognostic (4.82e-2)" "unprognostic (2.71e-1)" "unprognostic (4.95e-2)" "unprognostic (6.28e-2)" "potential prognostic unfavorable (2.82e-6)" "validated prognostic favorable (1.94e-9)" "validated prognostic favorable (1.15e-4)" "unprognostic (5.39e-3)" "unprognostic (3.99e-2)" "unprognostic (7.57e-3)" "unprognostic (8.54e-3)" "unprognostic (4.08e-1)" "unprognostic (9.14e-2)" "unprognostic (1.41e-1)" "unprognostic (8.48e-2)" "potential prognostic unfavorable (8.19e-4)" "unprognostic (9.75e-2)" "unprognostic (5.09e-2)" "unprognostic (4.11e-2)" "unprognostic (2.03e-3)" "potential prognostic favorable (3.39e-4)" "unprognostic (1.16e-2)" "unprognostic (1.54e-1)" "unprognostic (4.59e-2)" "unprognostic (5.58e-2)" "unprognostic (5.60e-2)" NKIRAS2 "DKFZP434N1526, kappaB-Ras2, KBRAS2" ENSG00000168256 "NFKB inhibitor interacting Ras like 2" Q9NYR9 17 42011382-42025644 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 121.6;Megakaryocytes: 80.4;Syncytiotrophoblasts: 77.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062861 Approved Nucleoplasm,Nucleoli NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 16: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 1 "Nucleoplasm, Nucleoli" "HPA062861: " "unprognostic (4.56e-1)" "unprognostic (6.30e-2)" "unprognostic (8.21e-2)" "unprognostic (3.61e-1)" "unprognostic (9.05e-2)" "unprognostic (2.38e-2)" "unprognostic (3.37e-1)" "unprognostic (3.85e-2)" "unprognostic (2.39e-2)" "unprognostic (3.31e-2)" "unprognostic (1.06e-2)" "unprognostic (6.93e-2)" "unprognostic (3.44e-1)" "validated prognostic unfavorable (2.71e-4)" "validated prognostic unfavorable (2.29e-4)" "unprognostic (9.28e-3)" "unprognostic (5.57e-2)" "unprognostic (2.15e-1)" "unprognostic (9.45e-2)" "unprognostic (3.43e-1)" "unprognostic (2.20e-1)" "unprognostic (1.15e-1)" "unprognostic (1.55e-2)" "unprognostic (3.18e-1)" "unprognostic (3.08e-1)" "unprognostic (2.17e-1)" "unprognostic (1.45e-2)" "unprognostic (2.13e-1)" "unprognostic (1.52e-1)" "unprognostic (5.18e-2)" "unprognostic (2.58e-1)" NKPD1 FLJ33600 ENSG00000179846 "NTPase KAP family P-loop domain containing 1" Q17RQ9 19 45149744-45160982 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "skin 1: 11.2" "Cell type enhanced" "Detected in many" "Epicardial cells: 6.8;Epididymal basal cells: 5.3;Late primary spermatocytes: 7.7;Retinal ganglion cells: 7.7;Suprabasal keratinocytes: 4.4" "Cell type enhanced" "Detected in many" "lower rhombic lip: 6.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Minor Salivary Gland - Minor salivary gland basal cells, Pituitary gland - Corticotropes, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA043339 Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 37: Skin - Keratinization" "Cluster 37: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 51: Secretory epithelial cells - Mixed function" "Plasma membrane, Cytosol" "Nucleoplasm, Vesicles" "HPA043339: " "unprognostic (1.49e-1)" "unprognostic (1.98e-1)" "unprognostic (5.68e-2)" "unprognostic (2.23e-1)" NKRF "ITBA4, NRF" ENSG00000186416 "NFKB repressing factor" O15226 X 119588337-119606443 "Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 41.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001476 Supported Nucleoplasm,Nucleoli NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 1: Neurons - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 75: Non-specific - Chaperones and protein folding" 100 Nucleoli Nucleoplasm "HPA001476: " "unprognostic (2.98e-1)" "unprognostic (6.10e-3)" "unprognostic (1.80e-2)" "unprognostic (1.76e-1)" "unprognostic (2.33e-2)" "unprognostic (1.86e-1)" "unprognostic (4.23e-2)" "unprognostic (1.03e-3)" "unprognostic (1.87e-3)" "unprognostic (1.83e-2)" "potential prognostic favorable (1.86e-5)" "unprognostic (4.28e-2)" "unprognostic (2.82e-2)" "unprognostic (3.24e-2)" "unprognostic (1.23e-2)" "unprognostic (2.91e-2)" "potential prognostic unfavorable (1.30e-5)" "unprognostic (1.08e-1)" "unprognostic (1.05e-1)" "unprognostic (3.34e-1)" "unprognostic (1.41e-1)" "unprognostic (6.82e-2)" "unprognostic (1.06e-2)" "unprognostic (1.30e-2)" "unprognostic (7.97e-3)" "unprognostic (2.45e-1)" "unprognostic (1.53e-1)" "unprognostic (1.68e-1)" "unprognostic (3.14e-2)" "unprognostic (2.73e-2)" "unprognostic (1.70e-1)" NKTR p104 ENSG00000114857 "Natural killer cell triggering receptor" P30414 3 42600655-42648735 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022120, HPA051576" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" No No "Cluster 21: Neutrophils - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 56: Non-specific - Sensory perception" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 16 "Nucleoplasm, Plasma membrane, Cytosol" "HPA022120: , HPA051576: " "potential prognostic favorable (5.56e-5)" "unprognostic (7.25e-2)" "unprognostic (2.72e-1)" "unprognostic (8.63e-2)" "unprognostic (5.77e-2)" "unprognostic (1.14e-1)" "unprognostic (6.53e-3)" "unprognostic (3.31e-2)" "potential prognostic favorable (6.80e-4)" "unprognostic (1.02e-2)" "potential prognostic unfavorable (9.72e-4)" "unprognostic (1.18e-1)" "unprognostic (1.93e-2)" "potential prognostic unfavorable (5.34e-4)" "unprognostic (2.67e-2)" "unprognostic (1.32e-1)" "unprognostic (4.49e-3)" "unprognostic (1.15e-1)" "potential prognostic favorable (3.52e-4)" "unprognostic (3.71e-1)" "unprognostic (1.23e-1)" "unprognostic (1.42e-2)" "unprognostic (7.23e-3)" "unprognostic (1.11e-2)" "unprognostic (1.94e-2)" "unprognostic (7.83e-2)" "unprognostic (1.05e-1)" "unprognostic (1.22e-1)" "unprognostic (2.93e-1)" "unprognostic (2.92e-2)" "unprognostic (2.93e-1)" NKX1-1 "HSPX153, SAX2" ENSG00000235608 "NK1 homeobox 1" Q15270 4 1402932-1406442 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in some" "medulla oblongata: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA029367 Uncertain Uncertain "Nucleoli fibrillar center,Cytosol" NA NA "Cluster 43: Hindbrain - Mixed function" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" Cytosol "Nucleoli fibrillar center" "HPA029367: " NKX1-2 "bB238F13.2, C10orf121" ENSG00000229544 "NK1 homeobox 2" Q9UD57 10 124445243-124450035 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 2.1;Breast secretory cells: 1.1;Respiratory basal cells: 2.1" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Testicular Germ Cell Tumor (TCGA): 11.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 13.2;testis cancer: 11.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA029367 Uncertain Approved "Nucleoli fibrillar center,Cytosol" NA NA "Cluster 53: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 26: Keratinocytes - Keratinization" Cytosol "Nucleoli fibrillar center" "HPA029367: " "unprognostic (1.08e-1)" "unprognostic (2.39e-2)" "unprognostic (6.03e-2)" "unprognostic (2.16e-1)" "unprognostic (2.10e-1)" NKX2-1 "BCH, NKX2A, TITF1, TTF-1, TTF1" ENSG00000136352 "NK2 homeobox 1" P43699 14 36516392-36521149 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "lung: 52.0;thyroid gland: 162.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 2.5;Alveolar cells type 2: 2.5;Respiratory deuterosomal cells: 1.0;Transitional alveolar cells: 3.0" "Group enriched" "Detected in some" 6 "LAMP5-LHX6 and Chandelier: 1.3;mammillary body: 2.2" "Group enriched" "Detected in some" 16 "Lung Adenocarcinoma (TCGA): 108.7;Thyroid Carcinoma (TCGA): 206.8" "Group enriched" "Detected in many" 5 "cerebral cortex: 13.2;hypothalamus: 38.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "lung cancer: 32.3;prostate cancer: 35.1;thyroid cancer: 42.4" "Lung - Alveolar cells type 2, Thyroid gland - Thyroid glandular cells" "Group enriched" "Detected in some" 5 "basal ganglia: 3.2;hypothalamus: 10.2" "Group enriched" "Detected in some" 13 "basal ganglia: 5.6;hypothalamus: 13.6" "CAB000078, CAB053633, HPA074316" Enhanced Uncertain "Golgi apparatus,Vesicles" NA NA "Cluster 33: Thyroid gland - Tissue development" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 81: Alveolar cells - Lung function" 14 "Golgi apparatus, Vesicles" "CAB000078: , CAB053633: , HPA074316: " "unprognostic (4.30e-2)" "unprognostic (4.88e-1)" "unprognostic (1.15e-2)" "unprognostic (1.52e-2)" "unprognostic (1.04e-3)" "unprognostic (2.92e-2)" "unprognostic (3.52e-1)" "unprognostic (1.12e-1)" "unprognostic (1.16e-1)" NKX2-2 "NKX2.2, NKX2B" ENSG00000125820 "NK2 homeobox 2" O95096 20 21511017-21514064 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 41.9" "Group enriched" "Detected in some" 4 "Bergmann glia: 113.9;Neuroendocrine cells: 121.7;Oligodendrocyte progenitor cells: 56.5;Oligodendrocytes: 72.8;Pancreatic islet cells: 71.0;Somatotrophs: 32.2" "Group enriched" "Detected in some" 6 "Bergmann glia: 101.1;committed oligodendrocyte precursor: 155.4;oligodendrocyte: 66.7;oligodendrocyte precursor cell: 58.9" "Group enriched" "Detected in some" 5 "Glioblastoma Multiforme (TCGA): 19.5;Pancreatic Adenocarcinoma (TCGA): 12.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "Bone cancer: 38.2" "Pancreas - Alpha cells, Pancreas - Beta cells, Pituitary gland - Somatotropes, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003468 Approved NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" "HPA003468: " "unprognostic (5.72e-1)" "unprognostic (1.16e-1)" "unprognostic (6.82e-2)" "unprognostic (2.71e-3)" "unprognostic (1.89e-2)" "unprognostic (1.87e-1)" "unprognostic (3.52e-2)" NKX2-3 "CSX3, NKX2.3, NKX2C, NKX4-3" ENSG00000119919 "NK2 homeobox 3" Q8TAU0 10 99532942-99536524 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "intestine: 35.2;lymphoid tissue: 28.3;salivary gland: 14.3" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 5.1;Hematopoietic stem cells: 13.1;Lymphatic endothelial cells: 3.6;Salivary basal cells: 23.5;Salivary duct cells: 5.0;Salivary ionocytes: 25.3;Vascular endothelial cells: 8.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Pancreatic Adenocarcinoma (TCGA): 4.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Minor Salivary Gland - Minor salivary gland ductal cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA047561 Uncertain Uncertain Nucleoli,Cytosol NA NA "Cluster 5: Spleen - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "Nucleoli, Cytosol" "HPA047561: " "unprognostic (1.88e-1)" "unprognostic (2.88e-1)" "potential prognostic favorable (6.79e-4)" "unprognostic (5.89e-2)" "unprognostic (1.38e-1)" "unprognostic (1.29e-1)" "unprognostic (4.50e-1)" "unprognostic (2.25e-2)" "unprognostic (1.56e-2)" NKX2-4 "NKX2.4, NKX2D" ENSG00000125816 "NK2 homeobox 4" Q9H2Z4 20 21395365-21397526 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "testis: 1.1" "Cell type enhanced" "Detected in some" "Early primary spermatocytes: 3.9;Early spermatids: 1.6;Late spermatids: 3.2;Undifferentiated spermatogonia: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in some" 8 "hypothalamus: 8.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Bone cancer: 9.3" "Region enriched" "Detected in single" 23 "hypothalamus: 2.7" "Region enriched" "Detected in single" 14 "hypothalamus: 1.3" HPA074996 Approved "Nuclear bodies" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 3: Early primary spermatocytes - Early meiosis" 2 "Nuclear bodies" "HPA074996: " NKX2-5 "CSX, CSX1, NKX2.5, NKX2E, NKX4-1" ENSG00000183072 "NK2 homeobox 5" P52952 5 173232109-173235311 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Atrial septal defect, Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "heart muscle: 233.9" "Cell type enriched" "Detected in some" 4 "Cardiomyocytes: 20.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 8.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 23.1" "Heart muscle - Cardiomyocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA065034 Supported Nucleoplasm,Cytosol NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 12 Nucleoplasm Cytosol "HPA065034: " "unprognostic (2.64e-1)" "unprognostic (1.97e-1)" "unprognostic (1.83e-2)" "unprognostic (1.97e-3)" "unprognostic (4.66e-3)" "unprognostic (1.98e-1)" "unprognostic (1.81e-1)" "unprognostic (2.62e-2)" "unprognostic (9.61e-2)" "unprognostic (4.57e-1)" "unprognostic (2.01e-1)" NKX2-6 "CSX2, NKX4-2" ENSG00000180053 "NK2 homeobox 6" A6NCS4 8 23701740-23706756 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "heart muscle: 1.0;salivary gland: 1.5" "Group enriched" "Detected in some" 10 "Cardiomyocytes: 3.8;Submucosal glandular cells: 2.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Neuroblastoma: 3.7;Sarcoma: 2.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA025288 Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" "Nuclear membrane" "Nucleoplasm, Cytosol" "HPA025288: " NKX2-8 "Nkx2-9, NKX2.8, NKX2H" ENSG00000136327 "NK2 homeobox 8" O15522 14 36580004-36582614 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 5.1;esophagus: 1.6;testis: 5.1" "Cell type enhanced" "Detected in some" "Esophageal apical cells: 20.9;Esophageal basal cells: 7.3;Esophageal suprabasal cells: 7.8;Late spermatids: 4.1;Oocytes: 4.6;Pituicytes/FSCs: 4.0;Respiratory ciliated cells: 3.5;Respiratory ionocytes: 10.2;Sertoli cells: 10.8;Transitional alveolar cells: 3.9" "Group enriched" "Detected in some" 4 "LAMP5-LHX6 and Chandelier: 4.6;lower rhombic lip: 2.7;mammillary body: 6.0;oligodendrocyte: 8.4" "Cancer enhanced" "Detected in some" "Thyroid Carcinoma (TCGA): 2.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 9.4;head and neck cancer: 9.1" "Adipose visceral - Mesothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA062879 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 67: Testis - Mixed function" "Cluster 30: White matter - Myelination" "Cluster 65: Non-specific - Unknown function" "Cluster 85: Squamous epithelial cells - Keratinization" 1 Nucleoplasm "Plasma membrane" "HPA062879: " "unprognostic (2.15e-1)" "unprognostic (2.51e-1)" "unprognostic (3.85e-1)" NKX3-1 "BAPX2, NKX3.1, NKX3A" ENSG00000167034 "NK3 homeobox 1" Q99801 8 23678697-23682938 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "prostate: 284.6" "Cell type enriched" "Detected in many" 19 "Prostatic glandular cells: 1231.7" "Low cell type specificity" "Detected in some" "Cancer enriched" "Detected in many" 61 "Prostate Adenocarcinoma (TCGA): 548.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "eosinophil: 54.2;neutrophil: 51.7" "Lineage enriched" "Detected in many" 21 "granulocytes: 54.2" "Cancer enriched" "Detected in many" 26 "prostate cancer: 238.2" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA025693, HPA078571" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 12 "Nucleoplasm, Cytosol" "HPA025693: , HPA078571: " "unprognostic (1.44e-1)" "unprognostic (7.16e-2)" "unprognostic (3.88e-2)" "unprognostic (1.11e-1)" "validated prognostic unfavorable (3.09e-6)" "validated prognostic unfavorable (1.34e-4)" "unprognostic (8.08e-3)" "unprognostic (2.90e-2)" "unprognostic (1.29e-3)" "unprognostic (1.14e-1)" "unprognostic (2.67e-1)" "unprognostic (2.04e-1)" "unprognostic (2.57e-1)" "unprognostic (5.19e-2)" "unprognostic (2.41e-2)" "unprognostic (1.77e-1)" "unprognostic (3.34e-2)" "unprognostic (1.42e-1)" "unprognostic (1.37e-1)" "unprognostic (1.94e-1)" "unprognostic (1.43e-2)" NKX3-2 "BAPX1, NKX3.2, NKX3B" ENSG00000109705 "NK3 homeobox 2" P78367 4 13540830-13544508 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" Dwarfism "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "intestine: 21.5" "Cell type enriched" "Detected in some" 5 "Breast lactating cells: 11.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 2.7" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA027564 Approved Approved Nucleoplasm NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 4: Breast lactating luminal cells - Lactation" 4 Nucleoplasm "HPA027564: " "unprognostic (1.53e-1)" "unprognostic (8.78e-3)" "unprognostic (1.96e-2)" "unprognostic (8.27e-2)" "unprognostic (2.98e-2)" "unprognostic (5.21e-2)" "unprognostic (4.87e-2)" NKX6-1 "Nkx6.1, NKX6A" ENSG00000163623 "NK6 homeobox 1" P78426 4 84491985-84499292 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 2.6;esophagus: 8.4;pancreas: 6.1;testis: 2.1;thyroid gland: 3.0" "Cell type enhanced" "Detected in some" "Ependymal cells: 9.3;Fibroblasts: 4.0;Late primary spermatocytes: 42.2;Pancreatic duct cells: 24.5;Pancreatic islet cells: 40.9" "Group enriched" "Detected in some" 21 "ependymal cell: 37.9;fibroblast: 20.3;pericyte: 21.5;vascular associated smooth muscle cell: 18.5" "Cancer enriched" "Detected in many" 9 "Kidney Chromophobe (TCGA): 41.5" "Region enhanced" "Detected in many" "midbrain: 30.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Bone cancer: 17.4" "Testis - Early spermatids, Testis - Late spermatids" "Region enhanced" "Detected in single" "pons and medulla: 1.6" "Group enriched" "Detected in many" 5 "hypothalamus: 4.6;medulla oblongata: 6.0;midbrain: 6.7;pons: 6.8;spinal cord: 14.2" "HPA036774, CAB070169" Enhanced Approved Nucleoplasm NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 1 Nucleoplasm "CAB070169: , HPA036774: " "unprognostic (2.29e-1)" "unprognostic (2.02e-1)" "unprognostic (3.75e-2)" "unprognostic (1.02e-1)" "unprognostic (2.50e-1)" "unprognostic (2.11e-1)" "unprognostic (5.34e-3)" "potential prognostic unfavorable (2.85e-4)" "unprognostic (8.15e-3)" "unprognostic (1.32e-2)" NKX6-2 "GTX, NKX6.1, NKX6B" ENSG00000148826 "NK6 homeobox 2" Q9C056 10 132783179-132786147 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding, Repressor" "Disease variant, Leukodystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 104.4" "Group enriched" "Detected in some" 9 "Foveolar cells: 100.9;Oligodendrocytes: 334.6" "Cell type enriched" "Detected in many" 4 "oligodendrocyte: 423.0" "Cancer enriched" "Detected in single" 6 "Glioblastoma Multiforme (TCGA): 5.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Stomach - Gastric mucous cells" "Region enriched" "Detected in many" 5 "white matter: 15.7" "Low region specificity" "Detected in all" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 38: Non-specific - Transcription" "Cluster 80: Oligodendrocytes - Myelination" "unprognostic (2.11e-2)" "unprognostic (2.90e-2)" NKX6-3 FLJ25169 ENSG00000165066 "NK6 homeobox 3" A6NJ46 8 41645177-41650817 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 9.8;intestine: 10.2;stomach 1: 26.5" "Cell type enhanced" "Detected in some" "Foveolar cells: 1.1;Gastric progenitor cells: 5.1;Mucous neck cells: 1.2;Retinal amacrine cells: 2.8" "Cell type enhanced" "Detected in some" "cerebellar inhibitory: 2.6;LAMP5-LHX6 and Chandelier: 3.0;MGE interneuron: 2.4;upper rhombic lip: 2.4" "Group enriched" "Detected in some" 5 "Pancreatic Adenocarcinoma (TCGA): 5.3;Stomach Adenocarcinoma (TCGA): 5.6;Testicular Germ Cell Tumor (TCGA): 3.4;Uterine Corpus Endometrial Carcinoma (TCGA): 1.7" "Region enhanced" "Detected in some" "cerebellum: 4.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "Gastric cancer: 6.6" "Pancreas - Beta cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 77: Intestine - Digestion" "Cluster 2: Neurons - Nucleosome" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 109: Neurons - Neuronal signaling" "unprognostic (1.72e-2)" "unprognostic (3.02e-2)" "unprognostic (9.76e-2)" "unprognostic (2.93e-1)" NLE1 "FLJ10458, NLE" ENSG00000073536 "Notchless homolog 1" Q9NVX2 17 35128730-35142304 "Essential proteins, Predicted intracellular proteins" "Notch signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 23.6;Extravillous trophoblasts: 22.4;Gastric chief cells: 20.7;Migrating cytotrophoblasts: 23.9;Oocytes: 23.0;Pancreatic acinar cells: 27.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018807 Approved Supported Nucleoplasm,Nucleoli NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 34: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 17: Non-specific - RNA processing" 22 Nucleoli Nucleoplasm "HPA018807: " "unprognostic (9.51e-3)" "unprognostic (2.50e-2)" "unprognostic (3.12e-1)" "unprognostic (1.26e-3)" "unprognostic (1.18e-2)" "unprognostic (1.46e-2)" "unprognostic (2.64e-1)" "unprognostic (3.83e-2)" "unprognostic (4.46e-2)" "unprognostic (1.18e-1)" "potential prognostic favorable (4.92e-4)" "unprognostic (2.83e-1)" "unprognostic (1.30e-1)" "validated prognostic unfavorable (2.28e-7)" "validated prognostic unfavorable (3.28e-6)" "unprognostic (1.98e-2)" "unprognostic (2.29e-3)" "unprognostic (1.62e-1)" "unprognostic (1.99e-1)" "unprognostic (3.53e-2)" "unprognostic (3.90e-3)" "unprognostic (2.21e-2)" "unprognostic (1.16e-1)" "unprognostic (1.40e-1)" "potential prognostic favorable (3.68e-5)" "unprognostic (1.45e-2)" "unprognostic (2.77e-1)" "unprognostic (8.56e-2)" "unprognostic (2.73e-1)" "unprognostic (1.77e-1)" "unprognostic (4.95e-1)" NLGN1 KIAA1070 ENSG00000169760 "Neuroligin 1" Q8N2Q7 3 173396284-174294372 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Biological rhythms, Cell adhesion" "Autism, Autism spectrum disorder, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.9;retina: 10.2" "Cell type enhanced" "Detected in many" "Bergmann glia: 2031.3;Brain excitatory neurons: 2520.1;Brain inhibitory neurons: 2278.4;Choroid plexus epithelial cells: 2267.6;Lactotrophs: 2989.7;Oligodendrocyte progenitor cells: 5377.0;Oligodendrocytes: 2349.8;Other brain neurons: 1592.0;Proximal tubule cells: 1250.4;Thyrotrophs: 1127.4" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in some" 8 "Glioblastoma Multiforme (TCGA): 12.7;Kidney Renal Clear Cell Carcinoma (TCGA): 9.8;Kidney Renal Papillary Cell Carcinoma (TCGA): 7.1;Skin Cutaneous Melanoma (TCGA): 8.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 12.1" "Pituitary gland - Lactotropes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006572, HPA006680, CAB033261" Enhanced Uncertain "Nuclear bodies,Plasma membrane" "Intracellular and membrane" "Cell adhesion" NA NA 79000 "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 69: Skin cancer - ECM organization" "Cluster 35: Neurons - Synaptic function & neurogenesis" 2 "Plasma membrane" "Nuclear bodies" "CAB033261: , HPA006572: , HPA006680: " "unprognostic (7.20e-2)" "unprognostic (1.49e-1)" "unprognostic (3.69e-2)" "potential prognostic favorable (4.65e-5)" "unprognostic (5.01e-2)" "unprognostic (3.10e-1)" "unprognostic (1.67e-1)" "unprognostic (4.45e-2)" "unprognostic (4.40e-2)" "unprognostic (6.69e-2)" "unprognostic (1.91e-1)" "unprognostic (1.69e-1)" NLGN2 KIAA1366 ENSG00000169992 "Neuroligin 2" Q8NFZ4 17 7404874-7419860 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Astrocytes: 36.2;Bergmann glia: 34.7;Brain excitatory neurons: 28.1;Brain inhibitory neurons: 36.6;Oligodendrocyte progenitor cells: 67.7;Oligodendrocytes: 27.4;Other brain neurons: 31.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Liver - Vascular endothelial cells" "Low region specificity" "Detected in all" "HPA055321, HPA069278" Enhanced Approved Mitochondria NA NA "Cluster 64: Non-specific - Transcription" "Cluster 33: Neurons - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 18 Mitochondria "HPA055321: , HPA069278: " "unprognostic (4.09e-2)" "unprognostic (1.99e-1)" "unprognostic (6.04e-2)" "unprognostic (1.52e-1)" "unprognostic (1.32e-2)" "unprognostic (2.21e-1)" "unprognostic (1.27e-1)" "unprognostic (3.94e-2)" "unprognostic (2.78e-2)" "unprognostic (2.98e-1)" "unprognostic (3.65e-3)" "unprognostic (1.01e-1)" "unprognostic (3.35e-3)" "unprognostic (8.73e-2)" "unprognostic (7.65e-2)" "unprognostic (2.66e-1)" "unprognostic (2.48e-1)" "unprognostic (2.97e-2)" "unprognostic (9.05e-3)" "unprognostic (5.24e-2)" "unprognostic (2.01e-2)" "unprognostic (2.14e-2)" "unprognostic (3.63e-3)" "unprognostic (1.38e-1)" "unprognostic (3.88e-2)" "unprognostic (2.54e-1)" "unprognostic (3.46e-1)" "unprognostic (1.40e-1)" "potential prognostic unfavorable (5.76e-4)" "unprognostic (1.82e-1)" NLGN3 "ASPGX1, AUTSX1, HNL3, KIAA1480" ENSG00000196338 "Neuroligin 3" Q9NZ94 X 71144821-71175255 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion" "Asperger syndrome, Autism, Autism spectrum disorder, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 31.9;seminal vesicle: 11.4" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 20.4;Astrocytes: 34.6;Bergmann glia: 57.5;Brain inhibitory neurons: 20.7;Neutrophils: 22.8;Oligodendrocyte progenitor cells: 144.7;Oligodendrocytes: 58.2;Peritubular myoid cells: 33.8" "Cell type enhanced" "Detected in all" "oligodendrocyte precursor cell: 148.7" "Cancer enriched" "Detected in some" 17 "Glioblastoma Multiforme (TCGA): 39.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.0" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in some" "Rhabdoid: 5.5" "Adrenal gland - Adrenal cortex cells, Colon - Enteric glia cells, Stomach - Fibroblasts, Testis - Peritubular cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003183, HPA004066" Enhanced Supported "Golgi apparatus,Cell Junctions" "Intracellular and membrane" "Cell adhesion" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 6 "Golgi apparatus, Cell Junctions" "HPA003183: , HPA004066: " "unprognostic (5.53e-2)" "unprognostic (9.34e-2)" "unprognostic (1.69e-1)" "unprognostic (6.18e-2)" "unprognostic (9.79e-2)" "unprognostic (6.61e-2)" NLGN4X "HLNX, KIAA1260, NLGN, NLGN4" ENSG00000146938 "Neuroligin 4 X-linked" Q8N0W4 X 5840637-6228867 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion" "Asperger syndrome, Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.8;lymphoid tissue: 13.3;ovary: 13.8" "Cell type enhanced" "Detected in many" "Astrocytes: 175.0;Bergmann glia: 241.8;Brain excitatory neurons: 259.3;Brain inhibitory neurons: 245.1;Cone photoreceptor cells: 209.1;Endometrial luminal cells: 187.1;Endometrial stromal cells: 383.0;Oligodendrocyte progenitor cells: 871.7;Other brain neurons: 186.2;Ovarian stromal cells: 176.4;Pituicytes/FSCs: 739.7;Schwann cells: 324.8" "Cell type enhanced" "Detected in all" "oligodendrocyte precursor cell: 1009.9" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 18.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 24.2;testis cancer: 39.3" "Colon - Enteric glia cells, Liver - Hepatic stellate cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Testis - Spermatogonia" HPA001651 Approved NA NA "Cluster 65: Brain - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" "HPA001651: " "unprognostic (4.39e-2)" "unprognostic (3.47e-1)" "unprognostic (5.30e-2)" "unprognostic (5.49e-3)" "unprognostic (2.72e-1)" "unprognostic (4.62e-2)" "unprognostic (3.01e-2)" "unprognostic (2.19e-1)" "unprognostic (1.10e-3)" "potential prognostic favorable (3.82e-5)" "unprognostic (1.24e-1)" "unprognostic (1.42e-1)" "unprognostic (5.31e-3)" "unprognostic (1.13e-1)" "unprognostic (4.11e-2)" "unprognostic (3.54e-1)" "unprognostic (4.42e-2)" "unprognostic (2.97e-2)" "unprognostic (8.18e-2)" "unprognostic (3.42e-2)" "unprognostic (1.18e-1)" "unprognostic (1.39e-1)" "unprognostic (1.12e-1)" "unprognostic (1.39e-3)" "unprognostic (1.28e-1)" "unprognostic (1.70e-1)" NLGN4Y KIAA0951 ENSG00000165246 "Neuroligin 4 Y-linked" Q8NFZ3 Y 14522573-14845654 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 5.7;seminal vesicle: 6.9" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 217.7;Bergmann glia: 436.7;Brain excitatory neurons: 386.6;Brain inhibitory neurons: 420.0;Choroid plexus epithelial cells: 270.0;Microglia: 257.6;Oligodendrocyte progenitor cells: 1237.6;Oligodendrocytes: 281.8;Other brain neurons: 258.7;Pituicytes/FSCs: 217.2;Prostatic hillock cells: 230.9;Retinal bipolar cells: 264.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 5.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "testis cancer: 18.3" HPA001651 Approved "Intracellular and membrane" "Cell adhesion" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 34: Non-specific - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" "HPA001651: " "unprognostic (2.04e-1)" "unprognostic (1.37e-1)" "unprognostic (2.12e-1)" "unprognostic (3.67e-2)" "potential prognostic favorable (7.77e-5)" "unprognostic (2.31e-3)" "unprognostic (1.71e-1)" "unprognostic (1.68e-1)" "unprognostic (1.35e-1)" "unprognostic (1.06e-1)" "unprognostic (1.57e-1)" "unprognostic (3.57e-1)" "unprognostic (1.13e-2)" "unprognostic (9.40e-3)" "unprognostic (2.48e-1)" NLK ENSG00000087095 "Nemo like kinase" Q9UBE8 17 28041737-28196381 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 72.8" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 888.5;Cone photoreceptor cells: 931.6;Podocytes: 841.9;Retinal bipolar cells: 612.9;Retinal pigment epithelial cells: 989.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 45 "basophil: 30.0" "Lineage enriched" "Detected in single" 45 "granulocytes: 30.0" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018192, HPA056511" Approved Approved "Nucleoplasm,Nucleoli,Cell Junctions" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 18: Adrenal cortex cells - Steroidogensis" 32 Nucleoplasm "Nucleoli, Cell Junctions" "HPA018192: , HPA056511: " "unprognostic (8.81e-2)" "unprognostic (9.97e-3)" "unprognostic (1.01e-1)" "unprognostic (4.26e-2)" "unprognostic (2.02e-1)" "unprognostic (1.84e-1)" "unprognostic (3.00e-1)" "unprognostic (1.01e-1)" "unprognostic (5.76e-2)" "unprognostic (2.88e-1)" "potential prognostic favorable (3.62e-4)" "unprognostic (8.83e-3)" "unprognostic (4.55e-1)" "unprognostic (2.70e-2)" "unprognostic (1.16e-1)" "unprognostic (7.90e-2)" "unprognostic (2.48e-1)" "unprognostic (6.66e-2)" "unprognostic (4.56e-2)" "unprognostic (1.55e-2)" "unprognostic (3.93e-3)" "unprognostic (3.21e-3)" "potential prognostic unfavorable (1.13e-4)" "unprognostic (1.60e-2)" "unprognostic (3.09e-3)" "unprognostic (5.94e-2)" "unprognostic (2.74e-2)" "unprognostic (1.21e-1)" "unprognostic (2.29e-1)" "unprognostic (4.82e-2)" "unprognostic (5.40e-2)" NLN "AGTBP, KIAA1226" ENSG00000123213 Neurolysin Q9BYT8 5 65722205-65871725 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.6;intermediate monocyte: 3.3;myeloid DC: 2.2;non-classical monocyte: 2.3" "Group enriched" "Detected in many" 5 "dendritic cells: 2.2;monocytes: 3.3" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031862 Approved Approved Mitochondria Yes No 29000 "Cluster 40: Monocytes - Innate immune response" "Cluster 76: Non-specific - Metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 7: Liver cancer - Metabolism" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" Mitochondria "HPA031862: " "unprognostic (2.95e-1)" "unprognostic (4.45e-3)" "unprognostic (1.40e-1)" "unprognostic (5.41e-2)" "unprognostic (7.47e-2)" "unprognostic (7.05e-2)" "unprognostic (7.73e-2)" "unprognostic (4.53e-1)" "unprognostic (2.22e-2)" "unprognostic (6.74e-2)" "unprognostic (3.91e-3)" "unprognostic (1.75e-1)" "unprognostic (1.43e-1)" "potential prognostic unfavorable (3.62e-4)" "unprognostic (1.10e-2)" "unprognostic (2.41e-3)" "unprognostic (1.78e-2)" "unprognostic (8.12e-2)" "unprognostic (1.67e-1)" "unprognostic (4.23e-1)" "unprognostic (1.95e-2)" "unprognostic (1.55e-3)" "unprognostic (6.89e-3)" "unprognostic (3.30e-2)" "unprognostic (1.07e-1)" "unprognostic (1.01e-3)" "unprognostic (4.09e-2)" "unprognostic (1.16e-2)" "unprognostic (4.36e-2)" "unprognostic (4.82e-2)" "unprognostic (3.32e-2)" NLRC3 "CLR16.2, FLJ00348, NOD3" ENSG00000167984 "NLR family CARD domain containing 3" Q7RTR2 16 3539033-3577403 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 6.1;lymphoid tissue: 12.7" "Cell type enhanced" "Detected in many" "B-cells: 35.0;Cardiomyocytes: 96.9;Endometrial ciliated cells: 24.9;Epicardial cells: 61.4;Hematopoietic stem cells: 27.2;Innate lymphoid cells: 58.9;Megakaryocyte-Erythroid progenitors: 26.7;NK-cells: 107.6;Respiratory ciliated cells: 24.5;T-cells: 73.6;Thymocytes: 41.5" "Cell type enriched" "Detected in many" 9 "leukocyte: 91.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 5 "Leukemia: 10.5;lymphoma: 10.5" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Minor Salivary Gland - T-cells, Prostate - T-cells, Spleen - B-cells (Spleen), Stomach - T-cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA048062 Supported "Vesicles,Centriolar satellite,Cytosol" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 1 Cytosol "Vesicles, Centriolar satellite" "HPA048062: " "unprognostic (2.64e-2)" "unprognostic (1.29e-2)" "unprognostic (4.42e-3)" "unprognostic (2.03e-2)" "unprognostic (1.18e-1)" "unprognostic (2.17e-1)" "potential prognostic favorable (1.62e-4)" "unprognostic (4.14e-2)" "unprognostic (2.02e-1)" "potential prognostic favorable (9.36e-5)" "potential prognostic favorable (7.21e-4)" "unprognostic (3.94e-1)" "unprognostic (2.06e-1)" "unprognostic (6.70e-2)" "unprognostic (3.48e-3)" "unprognostic (2.00e-1)" "unprognostic (1.11e-1)" "unprognostic (3.46e-3)" "unprognostic (6.70e-2)" "unprognostic (1.50e-1)" NLRC4 "CARD12, CLAN, CLAN1, CLANA, CLANB, CLANC, CLAND, CLR2.1, ipaf" ENSG00000091106 "NLR family CARD domain containing 4" Q9NPP4 2 32224453-32265732 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Immunity, Inflammatory response, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 8.5;lymphoid tissue: 11.3" "Group enriched" "Detected in many" 4 "Cardiomyocytes: 139.4;Neutrophil progenitors: 320.1;Neutrophils: 348.1" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 36.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 49.6;intermediate monocyte: 57.2;myeloid DC: 32.5;neutrophil: 24.7;non-classical monocyte: 46.7" "Group enriched" "Detected in many" 28 "dendritic cells: 32.5;granulocytes: 24.7;monocytes: 57.2" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Kidney - Macrophages, Prostate - Macrophages, Spleen - Neutrophils_2, Thyroid gland - Macrophages" "Not detected" "Not detected" "HPA006592, HPA075894" Uncertain Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 9 Cytosol "Vesicles, Plasma membrane" "HPA006592: , HPA075894: " "unprognostic (2.48e-1)" "unprognostic (7.11e-2)" "unprognostic (1.59e-1)" "unprognostic (8.65e-3)" "unprognostic (3.08e-1)" "unprognostic (4.52e-2)" "unprognostic (7.36e-2)" "unprognostic (3.42e-2)" "unprognostic (4.59e-1)" "unprognostic (1.90e-1)" "unprognostic (3.27e-1)" "unprognostic (3.63e-3)" "unprognostic (2.93e-2)" "unprognostic (6.75e-2)" "unprognostic (2.36e-1)" "unprognostic (5.37e-2)" "unprognostic (1.06e-1)" "unprognostic (1.95e-1)" "unprognostic (2.66e-2)" NLRC5 "CLR16.1, FLJ21709, NOD27" ENSG00000140853 "NLR family CARD domain containing 5" Q86WI3 16 56989485-57083531 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 33.8;lymphoid tissue: 31.8" "Cell type enhanced" "Detected in many" "B-cells: 105.8;Colonocytes: 133.3;Goblet cells: 115.3;Neutrophil progenitors: 215.2;Neutrophils: 275.6;NK-cells: 107.7;pDCs: 142.1;Somatotrophs: 138.5;T-cells: 140.1" "Cell type enhanced" "Detected in many" "endothelial cell: 81.2;leukocyte: 200.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Prostate - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA060405, HPA074724" Supported Centrosome,Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 2 Cytosol Centrosome "HPA060405: , HPA074724: " "unprognostic (2.99e-2)" "unprognostic (2.71e-1)" "unprognostic (7.88e-2)" "unprognostic (8.76e-2)" "unprognostic (6.27e-2)" "unprognostic (1.76e-1)" "unprognostic (7.39e-2)" "unprognostic (2.68e-3)" "unprognostic (1.23e-2)" "unprognostic (3.94e-1)" "unprognostic (2.60e-3)" "unprognostic (7.07e-2)" "unprognostic (7.26e-2)" "unprognostic (9.82e-2)" "unprognostic (3.22e-3)" "unprognostic (5.41e-2)" "unprognostic (1.53e-1)" "unprognostic (8.17e-2)" "unprognostic (2.70e-1)" "unprognostic (3.98e-2)" "unprognostic (8.78e-3)" "unprognostic (2.28e-2)" "potential prognostic unfavorable (6.73e-5)" "unprognostic (4.01e-1)" "unprognostic (1.10e-1)" "unprognostic (2.15e-3)" "unprognostic (1.52e-2)" "unprognostic (2.50e-2)" "unprognostic (2.25e-1)" "unprognostic (8.88e-2)" "unprognostic (4.45e-2)" NLRP1 "CARD7, CLR17.1, DEFCAP, DKFZp586O1822, KIAA0926, NAC, NALP1, SLEV1, VAMAS1" ENSG00000091592 "NLR family pyrin domain containing 1" Q9C000 17 5499415-5619424 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Immunity, Inflammatory response, Innate immunity, Necrosis" "Hydrolase, Protease" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 139.7;Differentiating spermatogonia: 161.1;Early primary spermatocytes: 235.7;Microglia: 183.9;monocytes: 143.6;Neutrophils: 410.6;NK-cells: 165.3;T-cells: 157.4" "Group enriched" "Detected in many" 4 "central nervous system macrophage: 239.0;endothelial cell: 132.7;leukocyte: 187.7" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 7 "cerebral cortex: 68.0" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Myeloma: 20.5" "Breast - Endothelial cells, Colon - Endothelial cells, Skeletal muscle - Endothelial cells" "CAB009189, HPA064431" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 58: Skin - Keratinization" "Cluster 6: Non-specific - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 9 "Nucleoplasm, Cytosol" "CAB009189: , HPA064431: " "unprognostic (3.55e-2)" "unprognostic (4.01e-2)" "unprognostic (1.26e-2)" "unprognostic (2.03e-1)" "unprognostic (7.72e-2)" "unprognostic (2.20e-1)" "unprognostic (1.78e-1)" "unprognostic (1.51e-1)" "unprognostic (1.01e-3)" "unprognostic (1.23e-1)" "unprognostic (1.17e-2)" "unprognostic (1.30e-1)" "unprognostic (5.54e-1)" "unprognostic (2.59e-2)" "unprognostic (6.53e-3)" "unprognostic (2.99e-3)" "unprognostic (1.95e-1)" "unprognostic (7.49e-2)" "unprognostic (1.56e-1)" "unprognostic (3.94e-2)" "unprognostic (1.00e-1)" "unprognostic (9.04e-2)" "unprognostic (1.23e-1)" "unprognostic (8.21e-2)" "unprognostic (3.38e-1)" "unprognostic (3.19e-1)" "unprognostic (3.09e-1)" "unprognostic (1.73e-2)" "unprognostic (6.78e-2)" "unprognostic (1.71e-2)" "unprognostic (2.30e-1)" NLRP10 "CLR11.1, NALP10, NOD8, PAN5, Pynod" ENSG00000182261 "NLR family pyrin domain containing 10" Q86W26 11 7957537-7965447 "Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "breast: 1.3;skin 1: 4.6" "Cell type enhanced" "Detected in single" "Papillary tip epithelial cells: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Skin - Keratinocyte (granular)" "Region enhanced" "Detected in some" "olfactory bulb: 2.1" "HPA039498, HPA040101" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 37: Skin - Keratinization" "Cluster 9: Non-specific - Receptor signaling" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 1 Nucleoplasm Cytosol "HPA039498: , HPA040101: " NLRP11 "CLR19.6, NALP11, NOD17, PAN10, PYPAF6" ENSG00000179873 "NLR family pyrin domain containing 11" P59045 19 55785397-55836800 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 1.1;liver: 1.0" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 4.4;Early spermatids: 16.3;Late primary spermatocytes: 17.7;Late spermatids: 8.0;Oocytes: 27.6;Undifferentiated spermatogonia: 4.7" "Cell type enhanced" "Detected in single" "central nervous system macrophage: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 26 "lymphoma: 18.8;Myeloma: 20.3" "Minor Salivary Gland - Plasma cells" "Not detected" "Not detected" "HPA046402, HPA078027" Uncertain Supported Cytosol NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" Cytosol "HPA046402: , HPA078027: " "unprognostic (3.53e-3)" NLRP12 "CLR19.3, Monarch1, NALP12, PAN6, PYPAF7, RNO2" ENSG00000142405 "NLR family pyrin domain containing 12" P59046 19 53793741-53824403 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.7;lymphoid tissue: 4.2" "Group enriched" "Detected in some" 4 "Neutrophil progenitors: 127.1;Neutrophils: 292.0" "Cell type enhanced" "Detected in some" "leukocyte: 7.8" "Cancer enriched" "Detected in single" 6 "Testicular Germ Cell Tumor (TCGA): 4.4" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "basophil: 57.0;classical monocyte: 18.2;eosinophil: 23.2;neutrophil: 29.9" "Group enriched" "Detected in many" 5 "granulocytes: 57.0;monocytes: 18.2" "Cancer enhanced" "Detected in single" "Leukemia: 1.8" "Adipose visceral - Neutrophils, Kidney - Macrophages, Liver - Neutrophils, Lung - Neutrophils_2, Spleen - Neutrophils_2, Stomach - Neutrophils" "Not detected" "Not detected" "Not detected" "Not detected" HPA042981 Approved NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 3 "HPA042981: " "unprognostic (3.23e-1)" "unprognostic (6.80e-2)" "unprognostic (2.23e-1)" NLRP13 "CLR19.7, NALP13, NOD14, PAN13" ENSG00000173572 "NLR family pyrin domain containing 13" Q86W25 19 55891699-55932336 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "ovary: 1.1" "Cell type enriched" "Detected in some" 37 "Oocytes: 78.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Breast glandular cells" "Not detected" "Not detected" HPA060459 Uncertain NA NA "Cluster 75: Ovary - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 41: Oocytes - Oogenesis" "HPA060459: " NLRP14 "CLR11.2, GC-LRR, Nalp-iota, NALP14, NOD5, PAN8" ENSG00000158077 "NLR family pyrin domain containing 14" Q86W24 11 7020479-7071526 "Plasma proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Early primary spermatocytes: 5.6;Ependymal cells: 6.8;Late primary spermatocytes: 4.0;Loop of henle epithelial cells: 4.0;Oocytes: 9.2;Paneth cells: 3.9;Plasma cells: 5.8;Podocytes: 4.6;Proximal tubule cells: 7.0;Renal collecting duct intercalated cells: 5.8;Renal connecting tubule cells: 3.9;Retinal bipolar cells: 4.7;Rod photoreceptor cells: 5.2" "Cell type enriched" "Detected in many" 4 "ependymal cell: 8.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes, Minor Salivary Gland - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Testis - Early spermatids, Testis - Spermatocytes" "Not detected" "Not detected" HPA039477 Approved Uncertain Cytosol NA NA "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 78: Plasma cells - Antibody production & ER-stress response" Cytosol "HPA039477: " "unprognostic (1.78e-2)" NLRP2 "CLR19.9, FLJ20510, NALP2, NBS1, PAN1, PYPAF2" ENSG00000022556 "NLR family pyrin domain containing 2" Q9NX02 19 54953130-55001142 "Predicted intracellular proteins" "Apoptosis, Immunity, Inflammatory response, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 8.7;Endometrial secretory cells: 10.7;Extravillous trophoblasts: 35.5;Late primary spermatocytes: 12.2;Migrating cytotrophoblasts: 26.3;Oocytes: 32.2;Papillary tip epithelial cells: 8.8;Syncytiotrophoblasts: 16.5" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 48.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 54.6;testis cancer: 73.5" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA021183 Supported "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 39: Testis - Nuclear processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 5 "Golgi apparatus, Vesicles, Cytosol" "HPA021183: " "unprognostic (9.00e-2)" "unprognostic (5.20e-2)" "unprognostic (2.96e-2)" "unprognostic (1.73e-1)" "unprognostic (1.87e-1)" "unprognostic (2.07e-1)" "unprognostic (2.70e-3)" "unprognostic (5.08e-3)" "unprognostic (1.11e-1)" "unprognostic (4.21e-2)" "unprognostic (1.12e-1)" "unprognostic (7.61e-3)" "unprognostic (1.33e-1)" "unprognostic (1.41e-1)" "unprognostic (8.81e-2)" "unprognostic (3.72e-1)" "unprognostic (1.04e-1)" "unprognostic (1.98e-3)" "unprognostic (3.03e-1)" "unprognostic (2.78e-1)" "unprognostic (4.38e-2)" "unprognostic (6.21e-2)" "unprognostic (9.45e-2)" "unprognostic (1.93e-2)" "unprognostic (2.60e-1)" "unprognostic (2.89e-1)" "unprognostic (3.34e-2)" NLRP2B "CLRX.1, NALP2P, NLRP2P, NOD24, POP4" ENSG00000215174 "NLR family pyrin domain containing 2B" P0DMW2 X 57677067-57680260 "Predicted intracellular proteins" "Immunity, Innate immunity" "Signal transduction inhibitor" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.7" NA NA "Cluster 37: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 80: Oligodendrocytes - Myelination" NLRP3 "AGTAVPRL, AII, AVP, C1orf7, CIAS1, CLR1.1, DFNA34, FCAS, FCU, MWS, NALP3, PYPAF1" ENSG00000162711 "NLR family pyrin domain containing 3" 1 247416156-247449108 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 5 "bone marrow: 51.5" "Cell type enhanced" "Detected in some" "cDC: 28.6;Macrophages: 48.1;Microglia: 66.5;Monocyte progenitors: 23.8;monocytes: 259.6;Neutrophils: 173.2" "Cell type enriched" "Detected in many" 6 "central nervous system macrophage: 82.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 129.9" "Group enriched" "Detected in many" 23 "dendritic cells: 37.3;granulocytes: 129.9;monocytes: 35.6" "Cancer enriched" "Detected in many" 6 "Leukemia: 11.8" "Adrenal gland - Macrophages, Heart muscle - Macrophages, Minor Salivary Gland - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA012878 Uncertain NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 15: Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 28 "HPA012878: " "unprognostic (1.36e-1)" "unprognostic (6.46e-2)" "unprognostic (5.48e-2)" "unprognostic (1.18e-1)" "unprognostic (1.50e-1)" "unprognostic (2.22e-1)" "unprognostic (1.91e-3)" "unprognostic (3.73e-1)" "unprognostic (4.95e-2)" "unprognostic (2.12e-2)" "unprognostic (2.70e-2)" "unprognostic (4.78e-2)" "unprognostic (7.09e-2)" "unprognostic (1.30e-2)" "unprognostic (1.61e-1)" "unprognostic (1.06e-1)" "unprognostic (5.48e-3)" "unprognostic (6.44e-2)" NLRP4 "CLR19.5, CT58, FLJ32126, NALP4, PAN2, PYPAF4, RNH2" ENSG00000160505 "NLR family pyrin domain containing 4" Q96MN2 19 55836540-55881855 "Predicted intracellular proteins" "Inflammatory response" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 4.7;testis: 6.6" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 4.7;Early spermatids: 13.5;Late primary spermatocytes: 15.5;Late spermatids: 6.7;Microglia: 5.5;Oocytes: 50.7;Undifferentiated spermatogonia: 9.4" "Cell type enriched" "Detected in single" 6 "central nervous system macrophage: 3.8" "Cancer enriched" "Detected in single" 5 "Testicular Germ Cell Tumor (TCGA): 3.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "lymphoma: 6.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA062128 Approved Mitochondria NA NA "Cluster 39: Testis - Nuclear processes" "Cluster 30: White matter - Myelination" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" 2 Mitochondria "HPA062128: " "unprognostic (8.52e-2)" NLRP5 "CLR19.8, MATER, NALP5, PAN11, PYPAF8" ENSG00000171487 "NLR family pyrin domain containing 5" P59047 19 55999726-56061810 "Disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 60 "ovary: 6.2;parathyroid gland: 21.1" "Cell type enriched" "Detected in some" 14 "Oocytes: 165.8" "Low cell type specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Bone cancer: 1.3" "Breast - Breast glandular cells, Pituitary gland - Corticotropes, Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047260, HPA056271" Uncertain Supported "Golgi apparatus,Vesicles" NA NA "Cluster 69: Parathyroid gland - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 41: Oocytes - Oogenesis" "Golgi apparatus" Vesicles "HPA047260: , HPA056271: " "unprognostic (8.08e-2)" NLRP6 "CLR11.4, NALP6, PAN3, PYPAF5" ENSG00000174885 "NLR family pyrin domain containing 6" P59044 11 278407-285388 "Plasma proteins, Predicted intracellular proteins" "Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "intestine: 37.8" "Group enriched" "Detected in some" 5 "Enterocytes: 60.1;Neutrophils: 56.2" "Cell type enriched" "Detected in single" 7 "leukocyte: 2.8" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in many" 5 "cerebral cortex: 8.4" "Group enriched" "Detected in many" 4 "neutrophil: 15.5;non-classical monocyte: 4.6" "Group enriched" "Detected in many" 4 "granulocytes: 15.5;monocytes: 4.6" "Cancer enhanced" "Detected in some" "Leukemia: 1.2;Myeloma: 2.1" "Adipose visceral - Neutrophils, Kidney - Proximal tubular cells, Lung - Neutrophils_2, Skin - Macrophages, Spleen - Neutrophils_2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043681, HPA048500" Supported NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 12: Non-specific - Vasculature" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 9 "HPA043681: , HPA048500: " "unprognostic (1.62e-1)" "potential prognostic favorable (1.68e-6)" "unprognostic (6.94e-3)" "unprognostic (7.28e-3)" "validated prognostic favorable (5.35e-5)" "validated prognostic favorable (1.08e-4)" "unprognostic (2.85e-1)" "unprognostic (3.41e-2)" NLRP7 "CLR19.4, NALP7, NOD12, PAN7, PYPAF3" ENSG00000167634 "NLR family pyrin domain containing 7" Q8WX94 19 54923509-54966312 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "testis: 3.7" "Cell type enhanced" "Detected in some" "Early spermatids: 3.1;Late primary spermatocytes: 4.2;Late spermatids: 7.9;Loop of henle epithelial cells: 1.3;Oocytes: 4.6;Papillary tip epithelial cells: 1.6;pDCs: 3.5;Plasma cells: 2.2;Podocytes: 1.3;Renal collecting duct principal cells: 1.3;Undifferentiated spermatogonia: 4.4" "Cell type enhanced" "Detected in some" "leukocyte: 2.6" "Cancer enriched" "Detected in some" 9 "Testicular Germ Cell Tumor (TCGA): 13.2" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 6 "plasmacytoid DC: 3.9" "Lineage enriched" "Detected in single" 6 "dendritic cells: 3.9" "Cancer enhanced" "Detected in some" "lymphoma: 1.7;testis cancer: 1.3" HPA051382 Uncertain Uncertain "Golgi apparatus" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 79: Testis - Spermatogenesis" "Cluster 55: Lymphoma - Immune response" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 3 "Golgi apparatus" "HPA051382: " "unprognostic (1.01e-1)" "unprognostic (4.37e-1)" "unprognostic (1.51e-1)" NLRP8 "CLR19.2, NALP8, NOD16, PAN4" ENSG00000179709 "NLR family pyrin domain containing 8" Q86W28 19 55947832-55988629 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Breast lactating cells: 2.1;Foveolar cells: 2.6;Granulosa cells: 1.6;Müller glia: 1.7;Oocytes: 9.2;Prostatic glandular cells: 4.3;Retinal bipolar cells: 1.7;Retinal ganglion cells: 3.9;Thymocytes: 1.7;Undifferentiated spermatogonia: 3.7" "Low cell type specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Breast glandular cells, Prostate - Prostate glandular cells, Testis - Spermatogonia" "Not detected" "Not detected" HPA056989 Uncertain NA NA "Cluster 7: Liver cancer - Metabolism" "Cluster 11: Muller glia cells - Retinal homeostasis" "HPA056989: " NLRP9 "CLR19.1, NALP9, NOD6, PAN12" ENSG00000185792 "NLR family pyrin domain containing 9" Q7RTR0 19 55708438-55738402 "Predicted intracellular proteins" "Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "ovary: 1.9" "Group enriched" "Detected in some" 11 "Extravillous trophoblasts: 90.5;Oocytes: 128.9" "Low cell type specificity" "Detected in some" "Cancer enriched" "Detected in single" 40 "Testicular Germ Cell Tumor (TCGA): 26.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Prostate - Prostate glandular cells" "Not detected" "Not detected" HPA042623 Approved NA NA "Cluster 75: Ovary - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" "HPA042623: " "unprognostic (1.49e-2)" "unprognostic (1.60e-1)" NLRX1 "CLR11.3, NOD9" ENSG00000160703 "NLR family member X1" Q86UT6 11 119166568-119184016 "Predicted intracellular proteins" "Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 39.0" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 207.9;Esophageal suprabasal cells: 91.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 15.9" "Lineage enriched" "Detected in many" 4 "granulocytes: 15.9" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061516 Supported Supported "Plasma membrane,Mitochondria" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 24: Non-specific - Unknown function" "Cluster 85: Squamous epithelial cells - Keratinization" 6 Mitochondria "Plasma membrane" "HPA061516: " "unprognostic (1.15e-1)" "unprognostic (2.31e-2)" "unprognostic (5.83e-2)" "unprognostic (8.79e-2)" "unprognostic (9.32e-2)" "unprognostic (2.76e-1)" "unprognostic (1.26e-1)" "unprognostic (4.65e-2)" "unprognostic (2.38e-2)" "unprognostic (8.30e-2)" "potential prognostic favorable (2.31e-5)" "unprognostic (1.09e-1)" "potential prognostic favorable (5.12e-5)" "unprognostic (1.68e-1)" "unprognostic (1.39e-1)" "unprognostic (2.95e-3)" "unprognostic (2.46e-2)" "unprognostic (8.45e-2)" "unprognostic (2.87e-1)" "unprognostic (1.03e-1)" "unprognostic (1.59e-1)" "unprognostic (2.16e-2)" "unprognostic (3.00e-1)" "unprognostic (1.84e-1)" "unprognostic (6.52e-2)" "unprognostic (4.69e-1)" "unprognostic (3.02e-2)" "unprognostic (5.63e-3)" "unprognostic (2.44e-1)" "unprognostic (7.48e-2)" "potential prognostic favorable (2.90e-5)" NMB "MGC17211, MGC2277, MGC3936" ENSG00000197696 "Neuromedin B" P08949 15 84655129-84658563 "Predicted secreted proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 75.6" "Cell type enhanced" "Detected in many" "Epididymal basal cells: 90.3;Epididymal efferent duct absorptive cells: 60.5;Esophageal suprabasal cells: 55.8;Gastric progenitor cells: 73.1;Late primary spermatocytes: 66.0;Pancreatic duct cells: 151.6;Urothelial cells: 57.8" "Cell type enhanced" "Detected in many" "Bergmann glia: 15.4;ependymal cell: 13.5" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 277.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Region enriched" "Detected in all" 16 "olfactory bulb: 168.1" "Group enriched" "Detected in all" 5 "olfactory bulb: 59.4;pons: 19.1" "CAB019302, HPA068415" Approved Approved "Golgi apparatus,Plasma membrane,Focal adhesion sites,Cytosol" "Secreted to blood" Immunity NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 21: Non-specific - Metabolism" "Cluster 7: Liver cancer - Metabolism" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 1 "Golgi apparatus" "Plasma membrane, Focal adhesion sites, Cytosol" "CAB019302: , HPA068415: " "unprognostic (1.27e-1)" "unprognostic (1.72e-2)" "unprognostic (2.21e-1)" "unprognostic (1.08e-1)" "unprognostic (2.65e-2)" "unprognostic (4.32e-2)" "potential prognostic favorable (2.52e-4)" "unprognostic (1.33e-2)" "unprognostic (1.44e-1)" "unprognostic (2.85e-1)" "unprognostic (3.08e-2)" "unprognostic (4.15e-1)" "unprognostic (1.73e-2)" "unprognostic (3.15e-2)" "potential prognostic unfavorable (4.84e-8)" "potential prognostic unfavorable (8.50e-4)" "unprognostic (9.49e-2)" "unprognostic (2.23e-1)" "unprognostic (2.19e-1)" "unprognostic (2.28e-1)" "unprognostic (3.72e-2)" "unprognostic (9.18e-3)" "unprognostic (1.83e-2)" "unprognostic (2.43e-1)" "unprognostic (3.35e-2)" "unprognostic (2.81e-2)" "unprognostic (1.21e-1)" "unprognostic (2.08e-2)" "unprognostic (1.17e-1)" "unprognostic (4.85e-2)" "unprognostic (3.56e-1)" NMBR "BB1, BB1R, BRS1" ENSG00000135577 "Neuromedin B receptor" P28336 6 142058330-142147122 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 10.6;Early primary spermatocytes: 16.0;Ependymal cells: 10.9;Fallopian tube ciliated cells: 7.8;Late primary spermatocytes: 19.7;Other brain neurons: 9.7;Respiratory ciliated cells: 23.6" "Cell type enhanced" "Detected in many" "eccentric medium spiny neuron: 30.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA026665 Supported "Plasma membrane,Cytosol" NA NA "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 11: Neuronal - Sensory perception" "Cluster 109: Neurons - Neuronal signaling" "Plasma membrane, Cytosol" "HPA026665: " "unprognostic (2.53e-1)" NMD3 CGI-07 ENSG00000169251 "NMD3 ribosome export adaptor" Q96D46 3 161104696-161253532 "Essential proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 617.6;Pituitary stem cells: 287.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035019 Supported Nucleoplasm,Nucleoli NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 16: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 17 "Nucleoplasm, Nucleoli" "HPA035019: " "unprognostic (6.99e-2)" "unprognostic (9.58e-3)" "unprognostic (2.21e-2)" "unprognostic (9.50e-2)" "unprognostic (2.38e-1)" "unprognostic (7.32e-2)" "unprognostic (3.55e-2)" "unprognostic (1.59e-1)" "unprognostic (9.06e-3)" "unprognostic (3.14e-2)" "potential prognostic favorable (1.29e-6)" "unprognostic (2.73e-3)" "unprognostic (7.14e-2)" "unprognostic (5.78e-2)" "unprognostic (1.59e-1)" "unprognostic (3.22e-3)" "potential prognostic unfavorable (2.47e-4)" "unprognostic (8.56e-3)" "unprognostic (2.21e-1)" "unprognostic (2.01e-1)" "potential prognostic unfavorable (5.00e-6)" "validated prognostic unfavorable (3.08e-5)" "validated prognostic unfavorable (3.20e-4)" "unprognostic (5.10e-2)" "unprognostic (5.93e-2)" "unprognostic (3.33e-3)" "unprognostic (6.96e-3)" "unprognostic (2.32e-1)" "unprognostic (1.92e-1)" "unprognostic (8.27e-3)" "unprognostic (2.79e-1)" NME1 "NDPKA, NM23, NM23-H1" ENSG00000239672 "NME/NM23 nucleoside diphosphate kinase 1" P15531 17 51153559-51162428 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Differentiation, Endocytosis, Neurogenesis, Nucleotide metabolism" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 107.5;Gastric progenitor cells: 98.7;Late spermatids: 103.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008467, CAB040571, HPA041113, CAB080149, CAB080151, CAB080152" Supported Supported Cytosol NA NA 15000000 "Cluster 13: Non-specific - Mitochondria" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 14: Neurons - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 44: Plasma cells - Antibody production & secretion" 39 Cytosol "CAB040571: , CAB080149: , CAB080151: , CAB080152: , HPA008467: , HPA041113: " "unprognostic (1.54e-2)" "unprognostic (4.44e-2)" "unprognostic (4.52e-2)" "unprognostic (1.28e-1)" "unprognostic (5.03e-2)" "unprognostic (6.15e-2)" "unprognostic (4.09e-1)" "unprognostic (3.22e-1)" "unprognostic (6.47e-3)" "unprognostic (1.16e-3)" "validated prognostic unfavorable (2.65e-7)" "validated prognostic unfavorable (5.84e-6)" "potential prognostic unfavorable (1.18e-4)" "validated prognostic unfavorable (3.55e-8)" "validated prognostic unfavorable (3.12e-8)" "unprognostic (3.52e-3)" "potential prognostic unfavorable (1.40e-4)" "unprognostic (1.94e-1)" "unprognostic (6.85e-2)" "unprognostic (1.03e-2)" "unprognostic (2.03e-1)" "unprognostic (9.71e-3)" "unprognostic (1.21e-1)" "unprognostic (8.18e-2)" "unprognostic (5.74e-2)" "unprognostic (2.47e-2)" "unprognostic (4.24e-2)" "unprognostic (1.87e-2)" "unprognostic (2.00e-1)" "unprognostic (5.99e-2)" "unprognostic (7.15e-2)" NME1-NME2 "NM23-LV, NMELV" ENSG00000011052 "NME1-NME2 readthrough" 17 51153590-51171744 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 47.6" "Cell type enhanced" "Detected in some" "Epicardial cells: 6.8;Gastric chief cells: 4.4;Retinal bipolar cells: 11.8;Rod photoreceptor cells: 10.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "CAB002169, HPA008467, HPA041113, CAB076057" Approved Approved Cytosol NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 7 Cytosol "CAB002169: , CAB076057: , HPA008467: , HPA041113: " "unprognostic (1.71e-1)" "unprognostic (5.81e-2)" "unprognostic (7.72e-2)" "unprognostic (2.27e-1)" "unprognostic (1.37e-1)" "unprognostic (6.31e-3)" "unprognostic (2.39e-2)" "unprognostic (3.32e-2)" "validated prognostic unfavorable (6.50e-4)" "validated prognostic unfavorable (5.49e-8)" "unprognostic (5.10e-2)" "unprognostic (4.76e-2)" "unprognostic (1.17e-1)" "unprognostic (1.01e-1)" "unprognostic (3.49e-2)" "unprognostic (1.02e-1)" "unprognostic (1.94e-1)" "unprognostic (4.09e-1)" "potential prognostic unfavorable (8.11e-6)" "unprognostic (2.12e-1)" "unprognostic (2.17e-2)" "unprognostic (2.03e-1)" "unprognostic (7.23e-2)" "unprognostic (1.83e-1)" "unprognostic (2.15e-1)" "unprognostic (1.21e-1)" "unprognostic (2.01e-1)" "unprognostic (4.78e-2)" NME2 "NDPKB, NM23-H2" ENSG00000243678 "NME/NM23 nucleoside diphosphate kinase 2" P22392 17 51165435-51171744 "Cancer-related genes, Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" "Nucleotide metabolism, Transcription, Transcription regulation" "Activator, DNA-binding, Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 20.9;Bergmann glia: 20.3;Brain excitatory neurons: 39.5;Brain inhibitory neurons: 34.4;Choroid plexus epithelial cells: 33.4;Endometrial secretory cells: 20.7;Ependymal cells: 22.5;Hepatic stellate cells: 38.7;Microglia: 35.0;Oligodendrocyte progenitor cells: 21.7;Oligodendrocytes: 38.5;Other brain neurons: 50.2;Parietal cells: 19.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB036214, CAB036215, HPA041113, CAB080057, CAB080059" Approved Supported Cytosol NA NA 14000000 "Cluster 13: Non-specific - Mitochondria" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 27: Breast cancer - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" 23 Cytosol "CAB036214: , CAB036215: , CAB080057: , CAB080059: , HPA041113: " "unprognostic (3.49e-2)" "unprognostic (4.36e-2)" "unprognostic (3.21e-1)" "unprognostic (1.99e-1)" "unprognostic (4.47e-3)" "unprognostic (1.28e-2)" "unprognostic (1.14e-1)" "unprognostic (7.47e-2)" "unprognostic (4.40e-3)" "unprognostic (1.85e-3)" "validated prognostic unfavorable (5.08e-5)" "validated prognostic unfavorable (4.34e-4)" "unprognostic (5.22e-3)" "validated prognostic unfavorable (4.23e-4)" "validated prognostic unfavorable (3.29e-5)" "unprognostic (3.25e-3)" "potential prognostic unfavorable (8.25e-4)" "unprognostic (2.08e-1)" "unprognostic (6.76e-2)" "unprognostic (4.70e-1)" "unprognostic (3.88e-1)" "unprognostic (7.71e-3)" "unprognostic (3.93e-2)" "unprognostic (1.14e-1)" "unprognostic (2.28e-1)" "unprognostic (2.33e-2)" "unprognostic (3.43e-1)" "unprognostic (2.91e-1)" "unprognostic (6.48e-2)" "unprognostic (1.22e-1)" "unprognostic (2.11e-2)" NME3 "DR-nm23, NDPKC, NM23-H3" ENSG00000103024 "NME/NM23 nucleoside diphosphate kinase 3" Q13232 16 1770320-1771561 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Nucleotide metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041113 Approved "Intracellular and membrane" Enzyme NA NA 2000000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 27: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 38 "HPA041113: " "unprognostic (1.14e-2)" "unprognostic (3.39e-2)" "unprognostic (6.76e-2)" "unprognostic (2.20e-1)" "unprognostic (5.03e-2)" "unprognostic (1.21e-1)" "unprognostic (8.95e-2)" "unprognostic (2.37e-1)" "unprognostic (2.35e-2)" "unprognostic (3.68e-1)" "unprognostic (1.11e-1)" "unprognostic (8.53e-2)" "unprognostic (2.47e-1)" "unprognostic (1.40e-3)" "unprognostic (2.93e-1)" "unprognostic (1.76e-1)" "unprognostic (1.17e-1)" "unprognostic (1.20e-2)" "unprognostic (9.64e-2)" "unprognostic (8.46e-2)" "unprognostic (1.73e-2)" "unprognostic (2.34e-1)" "unprognostic (4.95e-1)" "unprognostic (1.78e-1)" "unprognostic (3.60e-1)" "unprognostic (1.26e-1)" "unprognostic (4.24e-1)" "unprognostic (4.32e-2)" "unprognostic (1.21e-1)" "unprognostic (2.88e-1)" "unprognostic (2.79e-1)" NME4 "NDPKD, nm23-H4, NM23H4" ENSG00000103202 "NME/NM23 nucleoside diphosphate kinase 4" O00746 16 396725-410367 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Nucleotide metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 204.5;Epididymal efferent duct absorptive cells: 193.6;Erythrocyte progenitors: 372.5;Hofbauer cells: 217.0;Megakaryocytes: 259.6;Smooth muscle cells: 255.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB045997, HPA072588" Approved Supported Mitochondria Yes No "Cluster 29: Non-specific - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 44: Non-specific - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 62: Smooth muscle cells - Muscle contraction" 62 Mitochondria "CAB045997: , HPA072588: " "unprognostic (6.57e-2)" "unprognostic (2.60e-1)" "unprognostic (2.32e-2)" "potential prognostic unfavorable (8.32e-4)" "unprognostic (1.90e-1)" "unprognostic (1.27e-1)" "unprognostic (1.59e-1)" "unprognostic (1.71e-1)" "unprognostic (1.94e-1)" "unprognostic (1.12e-2)" "validated prognostic unfavorable (6.14e-7)" "validated prognostic unfavorable (1.16e-7)" "unprognostic (9.05e-2)" "unprognostic (1.15e-2)" "unprognostic (6.25e-3)" "potential prognostic unfavorable (4.08e-4)" "unprognostic (2.37e-2)" "unprognostic (3.81e-1)" "unprognostic (3.84e-2)" "unprognostic (1.81e-1)" "unprognostic (1.30e-1)" "unprognostic (1.44e-1)" "unprognostic (4.79e-2)" "potential prognostic favorable (6.84e-4)" "unprognostic (1.23e-1)" "unprognostic (2.51e-1)" "unprognostic (2.49e-2)" "unprognostic (9.41e-2)" "unprognostic (1.56e-1)" "unprognostic (4.89e-3)" "unprognostic (1.81e-2)" NME5 "nm23-H5, RSPH23" ENSG00000112981 "NME/NM23 family member 5" P56597 5 138115175-138139443 "Human disease related genes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein, Hydrolase" "Ciliopathy, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 35.0;testis: 49.8" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 251.8;Early spermatids: 647.6;Endometrial ciliated cells: 219.1;Ependymal cells: 328.2;Epididymal efferent duct ciliated cells: 259.8;Fallopian tube ciliated cells: 333.0;Late primary spermatocytes: 1077.9;Late spermatids: 351.1;Respiratory ciliated cells: 408.3" "Cell type enhanced" "Detected in all" "ependymal cell: 357.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 3.8" "Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044555, HPA058103" Enhanced Approved "Plasma membrane,Primary cilium,Cytosol" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" 10 Cytosol "Plasma membrane, Primary cilium" "HPA044555: , HPA058103: " "unprognostic (4.36e-2)" "unprognostic (5.63e-2)" "unprognostic (9.69e-3)" "potential prognostic unfavorable (8.53e-4)" "unprognostic (4.85e-2)" "potential prognostic favorable (4.85e-4)" "unprognostic (1.89e-2)" "potential prognostic favorable (1.25e-4)" "unprognostic (1.60e-1)" "unprognostic (5.58e-2)" "unprognostic (6.41e-2)" "unprognostic (3.53e-1)" "unprognostic (5.83e-2)" "unprognostic (2.15e-1)" "unprognostic (2.00e-2)" "unprognostic (3.43e-1)" "unprognostic (3.22e-1)" "unprognostic (1.17e-1)" "unprognostic (4.48e-2)" "unprognostic (1.06e-1)" "unprognostic (4.84e-2)" NME6 "IPIA-ALPHA, NM23-H6" ENSG00000172113 "NME/NM23 nucleoside diphosphate kinase 6" O75414 3 48290722-48301685 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Nucleotide metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 75.8;Cytotrophoblasts: 61.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017909 Approved Approved Vesicles NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 15: Non-specific - Transcription" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 4 Vesicles "HPA017909: " "unprognostic (1.93e-2)" "unprognostic (2.47e-3)" "unprognostic (2.58e-1)" "unprognostic (1.49e-1)" "unprognostic (8.24e-2)" "unprognostic (3.83e-1)" "unprognostic (2.95e-1)" "unprognostic (1.17e-2)" "unprognostic (2.56e-1)" "unprognostic (3.57e-2)" "unprognostic (6.85e-3)" "unprognostic (3.16e-2)" "unprognostic (3.01e-2)" "validated prognostic unfavorable (4.54e-8)" "validated prognostic unfavorable (1.54e-4)" "unprognostic (1.06e-1)" "unprognostic (8.56e-3)" "unprognostic (1.26e-1)" "unprognostic (1.29e-1)" "unprognostic (7.69e-2)" "unprognostic (1.80e-1)" "unprognostic (1.74e-2)" "unprognostic (2.09e-2)" "unprognostic (1.38e-1)" "unprognostic (1.76e-2)" "unprognostic (3.15e-1)" "unprognostic (1.91e-2)" "unprognostic (1.30e-1)" "unprognostic (2.21e-1)" "unprognostic (1.34e-1)" "unprognostic (1.85e-1)" NME7 "CFAP67, FLJ37194, NM23-H7" ENSG00000143156 "NME/NM23 family member 7" Q9Y5B8 1 169132531-169367948 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ependymal cells: 394.4;Epicardial cells: 366.1;Lactotrophs: 336.7;Respiratory ciliated cells: 371.5;Rod photoreceptor cells: 329.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028010, HPA028334, HPA038014, HPA054289" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 29: Forebrain - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 34: Ciliated cells - Cilia assembly & function" 86 Nucleoplasm Cytosol "HPA028010: , HPA028334: , HPA038014: , HPA054289: " "unprognostic (1.50e-2)" "unprognostic (1.64e-2)" "unprognostic (4.27e-1)" "unprognostic (2.21e-2)" "unprognostic (1.70e-1)" "unprognostic (6.25e-2)" "unprognostic (2.63e-1)" "unprognostic (1.16e-1)" "unprognostic (5.56e-3)" "unprognostic (1.11e-1)" "potential prognostic favorable (1.78e-5)" "unprognostic (4.80e-3)" "unprognostic (5.79e-2)" "potential prognostic unfavorable (1.92e-5)" "unprognostic (5.80e-2)" "unprognostic (1.96e-2)" "unprognostic (8.04e-2)" "unprognostic (2.83e-2)" "unprognostic (4.37e-3)" "unprognostic (2.32e-1)" "unprognostic (5.14e-3)" "unprognostic (2.21e-2)" "unprognostic (8.04e-3)" "unprognostic (5.75e-2)" "unprognostic (1.99e-2)" "unprognostic (8.78e-2)" "unprognostic (2.80e-1)" "unprognostic (4.95e-3)" "unprognostic (1.88e-1)" "unprognostic (1.18e-1)" "unprognostic (1.17e-1)" NME8 "CILD6, DNAI8, NM23-H8, SPTRX2, TXNDC3" ENSG00000086288 "NME/NM23 family member 8" Q8N427 7 37848597-37900397 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein, Hydrolase" "Ciliopathy, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "bone marrow: 11.6;testis: 9.7" "Group enriched" "Detected in some" 6 "Early spermatids: 33.9;Late primary spermatocytes: 74.6;Late spermatids: 27.7" "Cell type enhanced" "Detected in single" "leukocyte: 1.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 4.7" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in single" "Leukemia: 1.2" "Kidney - T-cells, Spleen - Neutrophils_2, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "CAB016416, HPA019259, HPA029572" Enhanced Supported "Nucleoplasm,Nuclear speckles,Primary cilium,Cytosol" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 30: White matter - Myelination" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 1 Cytosol "Nucleoplasm, Nuclear speckles, Primary cilium" "CAB016416: , HPA019259: , HPA029572: " "unprognostic (2.37e-1)" NME9 "NM23-H9, TXL-2, TXNDC6" ENSG00000181322 "NME/NM23 family member 9" Q86XW9 3 138261437-138329886 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 19.5;fallopian tube: 16.5" "Cell type enhanced" "Detected in many" "Adipocytes: 97.4;Cardiomyocytes: 165.4;Choroid plexus epithelial cells: 170.9;Ependymal cells: 263.8;Epicardial cells: 109.2;Fallopian tube ciliated cells: 95.8;Myonuclei: 102.3;Oligodendrocyte progenitor cells: 159.3;Respiratory ciliated cells: 159.7" "Cell type enhanced" "Detected in all" "ependymal cell: 279.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB020943, HPA040000, HPA043881" Enhanced Approved "Centriolar satellite,Cytosol" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" Cytosol "Centriolar satellite" "CAB020943: , HPA040000: , HPA043881: " "unprognostic (4.61e-2)" "unprognostic (4.44e-2)" "unprognostic (1.71e-1)" "unprognostic (2.75e-2)" "unprognostic (1.03e-3)" "unprognostic (1.94e-2)" "unprognostic (2.21e-2)" "unprognostic (7.53e-2)" "unprognostic (3.02e-2)" "unprognostic (2.79e-2)" "unprognostic (1.90e-1)" "unprognostic (9.60e-2)" "unprognostic (5.46e-2)" "unprognostic (3.31e-2)" NMI ENSG00000123609 "N-myc and STAT interactor" Q13287 2 151270470-151289894 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Megakaryocyte progenitors: 106.1;Megakaryocytes: 160.7;Migrating cytotrophoblasts: 121.7;Neutrophil progenitors: 113.3;Neutrophils: 259.8" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 29.9;endothelial cell: 27.7;leukocyte: 32.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008588 Approved Supported Nucleoplasm,Cytosol "Secreted to blood" Immunity NA NA 16000 "Cluster 28: Neutrophils - Unknown function" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 39: Astrocytes - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 53 "Nucleoplasm, Cytosol" "HPA008588: " "unprognostic (4.26e-2)" "unprognostic (4.30e-2)" "unprognostic (1.89e-1)" "unprognostic (6.75e-2)" "unprognostic (2.11e-1)" "unprognostic (1.94e-1)" "unprognostic (3.02e-2)" "unprognostic (2.23e-2)" "unprognostic (4.64e-1)" "unprognostic (3.41e-2)" "unprognostic (1.12e-3)" "unprognostic (3.38e-1)" "unprognostic (7.28e-2)" "unprognostic (1.77e-3)" "unprognostic (2.60e-1)" "potential prognostic unfavorable (3.89e-4)" "unprognostic (9.60e-3)" "unprognostic (4.07e-2)" "unprognostic (1.27e-1)" "unprognostic (2.02e-1)" "unprognostic (3.85e-2)" "validated prognostic unfavorable (4.23e-4)" "validated prognostic unfavorable (7.40e-4)" "unprognostic (3.15e-1)" "unprognostic (5.00e-3)" "unprognostic (3.50e-2)" "unprognostic (4.70e-2)" "unprognostic (2.03e-1)" "unprognostic (4.42e-2)" "unprognostic (1.79e-1)" "unprognostic (1.96e-1)" NMNAT1 "LCA9, NMNAT, PNAT1" ENSG00000173614 "Nicotinamide nucleotide adenylyltransferase 1" Q9HAN9 1 9943428-9985501 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Nucleotidyltransferase, Transferase" "Deafness, Disease variant, Dwarfism, Intellectual disability, Leber congenital amaurosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 106.9;Distal convoluted tubule cells: 55.3;Loop of henle epithelial cells: 52.2;Myonuclei: 107.7" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 77.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059447 Approved Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 52: Non-specific - Cellular respiration" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 37: Non-specific - mRNA processing" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 31 "Nucleoplasm, Nuclear bodies" "HPA059447: " "unprognostic (3.58e-2)" "unprognostic (1.72e-2)" "unprognostic (2.86e-2)" "unprognostic (3.34e-3)" "unprognostic (1.13e-3)" "unprognostic (1.33e-1)" "unprognostic (1.33e-1)" "unprognostic (6.66e-2)" "unprognostic (7.91e-2)" "unprognostic (1.38e-1)" "potential prognostic favorable (3.85e-5)" "unprognostic (6.84e-3)" "potential prognostic favorable (8.56e-7)" "unprognostic (1.70e-1)" "unprognostic (1.76e-2)" "unprognostic (1.23e-1)" "unprognostic (1.92e-1)" "unprognostic (3.35e-1)" "unprognostic (7.28e-2)" "unprognostic (1.00e-2)" "unprognostic (6.63e-2)" "unprognostic (8.90e-2)" "unprognostic (1.40e-1)" "unprognostic (2.45e-1)" "unprognostic (6.19e-3)" "unprognostic (1.08e-1)" "unprognostic (1.82e-2)" "unprognostic (3.67e-2)" "unprognostic (1.66e-1)" "unprognostic (6.86e-2)" "unprognostic (1.02e-2)" NMNAT2 "C1orf15, KIAA0479, PNAT2" ENSG00000157064 "Nicotinamide nucleotide adenylyltransferase 2" Q9BZQ4 1 183248237-183418380 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 79.6" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 138.3;Brain excitatory neurons: 315.7;Brain inhibitory neurons: 314.2;Corticotrophs: 127.9;Gonadotrophs: 122.8;Lactotrophs: 266.6;Oligodendrocyte progenitor cells: 149.4;Other brain neurons: 253.6;Retinal amacrine cells: 175.9;Retinal ganglion cells: 312.9;Sertoli cells: 251.7;Somatotrophs: 205.6;Thyrotrophs: 261.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 39.2;testis cancer: 23.1" "Breast - Endothelial cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015708, HPA061714" Enhanced Supported Cytosol NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 2 Cytosol "HPA015708: , HPA061714: " "unprognostic (2.59e-2)" "unprognostic (2.66e-1)" "unprognostic (4.97e-2)" "unprognostic (3.00e-2)" "unprognostic (7.05e-2)" "unprognostic (9.87e-2)" "potential prognostic favorable (1.16e-4)" "unprognostic (2.55e-3)" "unprognostic (8.48e-2)" "unprognostic (3.00e-3)" "potential prognostic unfavorable (8.48e-4)" "unprognostic (1.26e-1)" "unprognostic (2.19e-1)" "unprognostic (1.17e-1)" "unprognostic (1.82e-2)" "unprognostic (4.85e-2)" "potential prognostic favorable (3.67e-4)" "unprognostic (8.28e-3)" "unprognostic (3.66e-1)" "unprognostic (5.34e-2)" "unprognostic (1.41e-1)" NMNAT3 PNAT3 ENSG00000163864 "Nicotinamide nucleotide adenylyltransferase 3" Q96T66 3 139560180-139678017 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 179.9;Late primary spermatocytes: 172.0;Late spermatids: 333.2;Megakaryocyte progenitors: 169.7;Myonuclei: 152.7;Rod photoreceptor cells: 178.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Skin - Keratinocyte (other), Spleen - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA039077, HPA057402" Approved Supported Mitochondria NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 40: Non-specific - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 79: Photoreceptor cells - Phototransduction" Mitochondria "HPA039077: , HPA057402: " "unprognostic (4.26e-1)" "unprognostic (1.07e-1)" "unprognostic (1.02e-1)" "unprognostic (2.31e-1)" "unprognostic (1.02e-2)" "unprognostic (6.86e-2)" "unprognostic (3.96e-2)" "potential prognostic unfavorable (2.15e-5)" "unprognostic (4.25e-1)" "potential prognostic unfavorable (8.58e-4)" "unprognostic (1.31e-1)" "potential prognostic favorable (1.67e-4)" "unprognostic (1.07e-1)" "unprognostic (9.51e-2)" "unprognostic (3.75e-2)" "unprognostic (2.09e-1)" "unprognostic (1.23e-1)" "unprognostic (8.22e-2)" "unprognostic (2.11e-1)" "unprognostic (2.57e-2)" "unprognostic (2.92e-1)" "unprognostic (2.76e-2)" "unprognostic (3.85e-2)" "unprognostic (1.02e-1)" "unprognostic (4.98e-2)" "unprognostic (3.89e-3)" "unprognostic (5.87e-3)" "unprognostic (1.79e-1)" "unprognostic (2.46e-1)" "potential prognostic unfavorable (7.17e-4)" "unprognostic (1.64e-2)" NMRAL1 "FLJ25918, HSCARG, SDR48A1" ENSG00000153406 "NmrA like redox sensor 1" Q9HBL8 16 4461691-4495763 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 58.7;Gastric chief cells: 59.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041353, HPA062287" Uncertain Enhanced Nucleoplasm NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 14 Nucleoplasm "HPA041353: , HPA062287: " "unprognostic (1.01e-2)" "unprognostic (1.48e-1)" "unprognostic (1.58e-1)" "potential prognostic favorable (5.13e-5)" "unprognostic (9.90e-2)" "unprognostic (6.97e-2)" "unprognostic (1.15e-3)" "unprognostic (1.61e-3)" "unprognostic (9.50e-2)" "unprognostic (1.62e-2)" "unprognostic (1.00e-2)" "unprognostic (4.94e-3)" "unprognostic (2.24e-2)" "unprognostic (2.70e-1)" "unprognostic (1.62e-1)" "unprognostic (1.41e-1)" "unprognostic (3.37e-2)" "unprognostic (1.31e-1)" "unprognostic (4.76e-1)" "unprognostic (2.22e-1)" "unprognostic (1.52e-2)" "unprognostic (2.78e-2)" "unprognostic (4.89e-1)" "unprognostic (1.94e-1)" "unprognostic (9.26e-2)" "unprognostic (1.05e-2)" "unprognostic (2.77e-1)" "unprognostic (1.67e-1)" "unprognostic (2.35e-1)" "unprognostic (3.58e-2)" "unprognostic (8.66e-2)" NMRK1 "bA235O14.2, C9orf95, FLJ20559, NRK1" ENSG00000106733 "Nicotinamide riboside kinase 1" Q9NWW6 9 75060573-75088217 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 7 "Esophageal apical cells: 1132.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049795 Approved Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 11: T-cells - Unknown function" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 84: Apical squamous epithelium - Cornification" 3 "Nucleoplasm, Cytosol" Centrosome "HPA049795: " "unprognostic (8.44e-3)" "unprognostic (2.64e-2)" "unprognostic (7.19e-2)" "unprognostic (6.01e-3)" "unprognostic (1.89e-2)" "unprognostic (1.03e-2)" "unprognostic (6.36e-2)" "unprognostic (1.76e-2)" "unprognostic (2.90e-2)" "potential prognostic favorable (9.23e-8)" "unprognostic (6.57e-3)" "potential prognostic favorable (2.99e-4)" "unprognostic (2.41e-2)" "unprognostic (1.12e-1)" "unprognostic (2.71e-2)" "unprognostic (6.02e-2)" "unprognostic (8.52e-2)" "unprognostic (1.39e-2)" "unprognostic (2.80e-1)" "unprognostic (2.24e-1)" "unprognostic (2.41e-1)" "unprognostic (1.74e-1)" "unprognostic (2.58e-1)" "unprognostic (1.31e-1)" "unprognostic (3.45e-1)" "unprognostic (1.95e-1)" "unprognostic (1.52e-1)" "unprognostic (3.19e-1)" "unprognostic (1.88e-2)" NMRK2 "ITGB1BP3, MIBP, NRK2" ENSG00000077009 "Nicotinamide riboside kinase 2" Q9NPI5 19 3933069-3942416 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 88 "heart muscle: 1378.3;skeletal muscle: 590.6;tongue: 669.1" "Group enriched" "Detected in some" 10 "Cardiomyocytes: 140.2;Myonuclei: 165.3;Oocytes: 138.2;Thymic myoid cells: 46.2" "Group enriched" "Detected in some" 8 "deep-layer near-projecting: 1.9;vascular associated smooth muscle cell: 5.6" "Cancer enhanced" "Detected in some" "Kidney Chromophobe (TCGA): 48.9;Kidney Renal Papillary Cell Carcinoma (TCGA): 131.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "liver cancer: 2.9;skin cancer: 3.9;testis cancer: 5.6" "Heart muscle - Cardiomyocytes, Pituitary gland - Gonadotropes, Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA049909, HPA054792, HPA072450" Approved Enhanced Nucleoplasm,Vesicles NA NA "Cluster 41: Striated muscle - Muscle contraction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 34: Testis cancer - Unknown function" "Cluster 55: Myocytes - Oxidative muscle function" 2 Nucleoplasm Vesicles "HPA049909: , HPA054792: , HPA072450: " "unprognostic (5.46e-3)" "unprognostic (3.91e-3)" "unprognostic (6.44e-2)" "unprognostic (1.39e-1)" "unprognostic (1.93e-1)" "unprognostic (7.16e-2)" "unprognostic (2.33e-2)" NMS ENSG00000204640 "Neuromedin S" Q5H8A3 2 100470482-100483280 "Predicted secreted proteins" Neuropeptide "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "brain: 1.0" "Cell type enhanced" "Detected in some" "Early spermatids: 2.2;Foveolar cells: 1.0;Other brain neurons: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in many" "medulla oblongata: 5.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "basal ganglia: 2.4;hypothalamus: 5.4;pons and medulla: 1.3" "Secreted in brain" Neuropeptide NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 43: Hindbrain - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" NMT1 NMT ENSG00000136448 "N-myristoyltransferase 1" P30419 17 44957992-45109016 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 424.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022949, HPA022963" Supported Supported "Plasma membrane,Cytosol" NA NA 180000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 93: Hepatocytes - Bile production & excretion" 19 Cytosol "Plasma membrane" "HPA022949: , HPA022963: " "unprognostic (1.42e-1)" "unprognostic (4.72e-3)" "unprognostic (3.58e-1)" "unprognostic (2.16e-2)" "unprognostic (2.99e-2)" "unprognostic (2.60e-2)" "unprognostic (3.43e-1)" "unprognostic (1.91e-2)" "unprognostic (3.04e-2)" "potential prognostic unfavorable (5.41e-4)" "unprognostic (1.09e-3)" "unprognostic (1.17e-1)" "unprognostic (8.36e-2)" "unprognostic (1.88e-2)" "unprognostic (1.49e-1)" "unprognostic (2.73e-2)" "unprognostic (1.54e-2)" "unprognostic (5.44e-2)" "unprognostic (5.18e-2)" "potential prognostic unfavorable (5.84e-4)" "unprognostic (2.10e-2)" "unprognostic (7.08e-2)" "potential prognostic unfavorable (1.24e-4)" "unprognostic (1.23e-1)" "unprognostic (1.08e-3)" "unprognostic (2.70e-2)" "unprognostic (2.34e-1)" "unprognostic (6.44e-2)" "unprognostic (2.96e-1)" "unprognostic (1.07e-1)" "unprognostic (8.01e-2)" NMT2 ENSG00000152465 "N-myristoyltransferase 2" O60551 10 15102584-15168693 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 193.6;Mast cells: 189.7;Sertoli cells: 205.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "basophil: 14.5;eosinophil: 13.6;gdT-cell: 11.0;MAIT T-cell: 19.8;memory CD4 T-cell: 17.5;memory CD8 T-cell: 12.8;naive CD4 T-cell: 21.8;naive CD8 T-cell: 14.5;NK-cell: 20.9;T-reg: 29.5" "Group enriched" "Detected in many" 9 "granulocytes: 14.5;NK-cells: 20.9;T-cells: 29.5" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Prostate - Fibroblasts, Testis - Sertoli cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001303 Approved Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 61: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 72: Neuronal - Signal transduction" "Cluster 58: Mast cells - Allergic inflammatory responses" 29 "Golgi apparatus, Plasma membrane, Cytosol" "HPA001303: " "unprognostic (4.36e-1)" "unprognostic (1.36e-1)" "unprognostic (1.23e-1)" "unprognostic (1.27e-1)" "unprognostic (5.93e-2)" "unprognostic (3.99e-1)" "unprognostic (3.98e-2)" "potential prognostic favorable (3.13e-5)" "unprognostic (3.53e-1)" "unprognostic (1.87e-1)" "potential prognostic favorable (1.12e-7)" "unprognostic (8.11e-2)" "unprognostic (1.70e-2)" "unprognostic (2.97e-2)" "unprognostic (1.29e-1)" "unprognostic (5.63e-2)" "unprognostic (2.90e-1)" "unprognostic (4.87e-2)" "potential prognostic unfavorable (8.50e-4)" "unprognostic (6.01e-2)" "unprognostic (3.07e-2)" "unprognostic (9.06e-2)" "unprognostic (1.48e-1)" "unprognostic (3.07e-1)" "unprognostic (3.05e-2)" "unprognostic (1.44e-3)" "unprognostic (2.02e-1)" "unprognostic (7.02e-3)" "unprognostic (2.88e-1)" "unprognostic (2.60e-2)" "unprognostic (7.73e-2)" NMU ENSG00000109255 "Neuromedin U" P48645 4 55595229-55636698 "Predicted secreted proteins" Neuropeptide "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 96.3;skin 1: 36.3;vagina: 29.4" "Group enriched" "Detected in many" 4 "Esophageal apical cells: 410.5;Esophageal basal cells: 344.3;Esophageal suprabasal cells: 580.9;Suprabasal keratinocytes: 233.8" "Group enriched" "Detected in some" 7 "MGE interneuron: 38.6;splatter: 9.7;thalamic excitatory: 30.1" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "thalamus: 15.4" "Group enriched" "Detected in some" 10 "MAIT T-cell: 3.6;memory CD4 T-cell: 1.1" "Lineage enriched" "Detected in single" 37 "T-cells: 3.6" "Low cancer specificity" "Detected in all" "Pituitary gland - Lactotropes, Prostate - Urothelial cells, Skin - Keratinocyte (other), Testis - Spermatogonia" "Group enriched" "Detected in some" 8 "hypothalamus: 1.1;pons and medulla: 4.5" "Low region specificity" "Detected in some" HPA025926 Uncertain "Secreted in other tissues" Neuropeptide NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 85: Squamous epithelial cells - Keratinization" 57 "HPA025926: " "unprognostic (9.03e-2)" "unprognostic (6.75e-3)" "unprognostic (1.50e-1)" "unprognostic (1.49e-1)" "unprognostic (7.93e-2)" "unprognostic (4.80e-2)" "unprognostic (4.30e-2)" "unprognostic (9.24e-2)" "unprognostic (3.12e-2)" "potential prognostic unfavorable (3.38e-6)" "unprognostic (6.22e-3)" "potential prognostic unfavorable (7.06e-4)" "unprognostic (7.62e-2)" "unprognostic (1.63e-3)" "unprognostic (3.93e-1)" "unprognostic (1.32e-1)" "unprognostic (9.66e-2)" "unprognostic (8.76e-2)" "unprognostic (1.16e-1)" "unprognostic (4.62e-3)" "unprognostic (2.13e-2)" "unprognostic (2.42e-1)" "unprognostic (5.67e-2)" "unprognostic (1.73e-1)" "unprognostic (1.51e-1)" "unprognostic (6.58e-2)" "unprognostic (2.24e-2)" "unprognostic (1.02e-3)" NMUR1 "FM-3, GPC-R, GPR66, NMU1R" ENSG00000171596 "Neuromedin U receptor 1" Q9HB89 2 231523187-231530445 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "retina: 7.6" "Cell type enhanced" "Detected in some" "Adipocytes: 7.3;Differentiating spermatogonia: 5.2;Early primary spermatocytes: 5.8;Innate lymphoid cells: 6.8;NK-cells: 35.9;Peritubular myoid cells: 10.3;Rod photoreceptor cells: 31.1;T-cells: 5.7" "Cell type enriched" "Detected in some" 9 "leukocyte: 18.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "gdT-cell: 18.0;MAIT T-cell: 4.5;memory CD8 T-cell: 8.7;naive CD8 T-cell: 5.1;NK-cell: 10.9" "Group enriched" "Detected in many" 23 "NK-cells: 10.9;T-cells: 18.0" "Cancer enhanced" "Detected in single" "Leukemia: 1.7" "Skeletal muscle - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA027895 Approved NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 42: Retina - Visual perception" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 1 "HPA027895: " "unprognostic (9.83e-3)" "unprognostic (2.48e-1)" "unprognostic (4.45e-2)" "unprognostic (1.11e-3)" "unprognostic (1.55e-1)" "unprognostic (2.10e-3)" "unprognostic (1.72e-1)" NMUR2 NMU2R ENSG00000132911 "Neuromedin U receptor 2" Q9GZQ4 5 152391546-152433368 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "stomach 1: 1.0;testis: 1.5" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 21.6;Foveolar cells: 20.9;Gastric progenitor cells: 10.3;Myonuclei: 9.8;Oligodendrocytes: 11.9;Retinal ganglion cells: 3.9;Sertoli cells: 17.4" "Cell type enhanced" "Detected in some" "endothelial cell: 10.0;oligodendrocyte: 28.6" "Group enriched" "Detected in some" 5 "Pancreatic Adenocarcinoma (TCGA): 3.2;Stomach Adenocarcinoma (TCGA): 3.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 4.5;pancreatic cancer: 8.1" "Testis - Sertoli cells" "Region enhanced" "Detected in single" "hypothalamus: 1.7" "Low region specificity" "Detected in all" "HPA027800, HPA045836" Enhanced Supported "Plasma membrane" NA NA "Cluster 67: Testis - Mixed function" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 55: Myocytes - Oxidative muscle function" 4 "Plasma membrane" "HPA027800: , HPA045836: " "unprognostic (3.24e-2)" "unprognostic (3.92e-2)" "unprognostic (1.78e-1)" "unprognostic (3.62e-2)" "unprognostic (1.64e-2)" NNAT Peg5 ENSG00000053438 Neuronatin Q16517 20 37521206-37523690 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Developmental protein" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 12 "brain: 914.4;pituitary gland: 1528.9" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 149.8;Corticotrophs: 863.3;Ependymal cells: 321.2;Epididymal efferent duct ciliated cells: 294.2;Lactotrophs: 219.9;Late spermatids: 122.4;Medullary thymic epithelial cells: 175.2;Other brain neurons: 137.8;Somatotrophs: 537.4;Thymic myoid cells: 163.2;Thyrotrophs: 105.0" "Cell type enhanced" "Detected in all" "ependymal cell: 331.2;medium spiny neuron: 409.7" "Group enriched" "Detected in many" 11 "Bladder Urothelial Carcinoma (TCGA): 56.9;Glioblastoma Multiforme (TCGA): 144.7;Testicular Germ Cell Tumor (TCGA): 106.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 150.4" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal medulla cells, Breast - Adipocytes (Breast), Pituitary gland - Corticotropes, Testis - Late spermatids" "Low region specificity" "Detected in all" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 1 "unprognostic (2.19e-1)" "unprognostic (1.59e-2)" "unprognostic (9.67e-3)" "unprognostic (2.25e-2)" "unprognostic (4.15e-3)" "unprognostic (2.28e-3)" "unprognostic (2.38e-3)" "unprognostic (1.23e-2)" "unprognostic (1.30e-1)" "unprognostic (2.95e-1)" "unprognostic (1.30e-1)" "unprognostic (3.38e-2)" "unprognostic (5.33e-2)" "unprognostic (1.53e-1)" "unprognostic (1.35e-1)" "unprognostic (5.02e-2)" "unprognostic (2.08e-2)" "unprognostic (1.54e-1)" "unprognostic (4.08e-2)" "unprognostic (2.43e-3)" "unprognostic (3.20e-2)" "unprognostic (1.17e-1)" "unprognostic (1.35e-1)" "unprognostic (1.19e-1)" NNMT ENSG00000166741 "Nicotinamide N-methyltransferase" P40261 11 114257787-114313536 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 297.1" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 748.3;Endometrial secretory cells: 624.9;Fibroblasts: 759.4;Hepatocytes: 4376.1;Lymphatic endothelial cells: 435.4;Mesothelial cells: 554.7;Myosatellite cells: 1317.3" "Cell type enhanced" "Detected in many" "CGE interneuron: 27.7;endothelial cell: 37.1" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 89.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 59.6" "Colon - Neutrophils, Liver - Neutrophils, Skin - Macrophages, Testis - Endothelial cells" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA059180 Approved Approved "Golgi apparatus,Cytosol" NA NA 360000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 12: Non-specific - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 108: Fibroblasts - ECM organization" 1 "Golgi apparatus" Cytosol "HPA059180: " "unprognostic (1.78e-1)" "unprognostic (1.83e-1)" "unprognostic (2.91e-1)" "unprognostic (2.43e-2)" "unprognostic (7.34e-2)" "unprognostic (2.33e-2)" "unprognostic (1.86e-1)" "unprognostic (3.01e-3)" "unprognostic (9.17e-3)" "unprognostic (3.38e-1)" "unprognostic (2.59e-2)" "unprognostic (5.59e-2)" "unprognostic (4.14e-1)" "unprognostic (5.68e-2)" "unprognostic (2.32e-3)" "unprognostic (6.90e-2)" "unprognostic (3.43e-1)" "unprognostic (7.25e-3)" "unprognostic (3.52e-2)" "unprognostic (2.26e-3)" "unprognostic (6.41e-3)" "unprognostic (3.09e-2)" "unprognostic (4.26e-1)" "unprognostic (5.29e-2)" "unprognostic (1.64e-1)" "unprognostic (2.52e-2)" "unprognostic (4.96e-2)" "potential prognostic unfavorable (4.23e-4)" "unprognostic (3.74e-2)" "unprognostic (1.02e-3)" "unprognostic (1.73e-1)" NNT ENSG00000112992 "Nicotinamide nucleotide transhydrogenase" Q13423 5 43602692-43707405 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Translocase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 223.6;tongue: 358.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 795.4;Choroid plexus epithelial cells: 278.3;Distal convoluted tubule cells: 275.7;Hepatocytes: 425.4;Myonuclei: 472.1;Parietal cells: 307.6" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 105.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Stomach - Parietal cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004829, CAB004975, HPA066564" Enhanced Approved Mitochondria NA NA 120000 "Cluster 33: Non-specific - ATP binding" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 23: Choroid plexus - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 55: Myocytes - Oxidative muscle function" 11 Mitochondria "CAB004975: , HPA004829: , HPA066564: " "unprognostic (1.03e-1)" "unprognostic (2.96e-1)" "unprognostic (4.73e-1)" "unprognostic (2.25e-1)" "unprognostic (7.90e-2)" "unprognostic (1.49e-1)" "unprognostic (6.72e-2)" "unprognostic (5.32e-2)" "unprognostic (6.25e-2)" "potential prognostic unfavorable (1.57e-4)" "potential prognostic favorable (2.05e-10)" "unprognostic (2.31e-2)" "unprognostic (3.06e-3)" "unprognostic (2.82e-2)" "unprognostic (1.04e-3)" "unprognostic (1.82e-2)" "unprognostic (7.17e-2)" "unprognostic (1.41e-1)" "unprognostic (2.47e-2)" "unprognostic (1.04e-1)" "unprognostic (1.96e-1)" "unprognostic (1.16e-1)" "unprognostic (1.87e-1)" "unprognostic (2.01e-1)" "unprognostic (8.60e-3)" "unprognostic (1.97e-2)" "unprognostic (1.03e-1)" "unprognostic (6.48e-2)" "unprognostic (1.61e-1)" "unprognostic (1.49e-1)" "unprognostic (2.29e-1)" NOA1 "C4orf14, hAtNOS1, hNOA1, MGC3232, MTG3" ENSG00000084092 "Nitric oxide associated 1" Q8NC60 4 56963350-56977606 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035838, HPA035839" Approved Supported Mitochondria NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 31: Non-specific - Transcription" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 30 Mitochondria "HPA035838: , HPA035839: " "unprognostic (5.31e-1)" "unprognostic (2.61e-2)" "unprognostic (6.71e-2)" "unprognostic (6.87e-3)" "unprognostic (1.00e-1)" "unprognostic (8.02e-2)" "unprognostic (5.82e-2)" "unprognostic (6.82e-2)" "unprognostic (7.82e-2)" "validated prognostic favorable (2.58e-8)" "validated prognostic favorable (3.96e-4)" "unprognostic (3.51e-1)" "unprognostic (2.16e-2)" "unprognostic (5.09e-2)" "unprognostic (1.55e-2)" "unprognostic (2.78e-1)" "unprognostic (7.11e-2)" "unprognostic (1.14e-1)" "unprognostic (1.11e-2)" "unprognostic (7.09e-3)" "unprognostic (2.62e-2)" "unprognostic (1.44e-2)" "unprognostic (8.04e-3)" "unprognostic (2.55e-1)" "unprognostic (2.42e-1)" "unprognostic (1.89e-1)" "unprognostic (1.53e-1)" "unprognostic (2.60e-1)" "unprognostic (4.85e-2)" NOB1 "ART-4, MST158, NOB1P, PSMD8BP1" ENSG00000141101 "NIN1 (RPN12) binding protein 1 homolog" Q9ULX3 16 69741871-69754926 "Essential proteins, Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 134.3;Esophageal basal cells: 159.9;Oocytes: 280.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041522, HPA049430, HPA067411" Approved Approved "Focal adhesion sites,Cytosol" NA NA 5700 "Cluster 33: Non-specific - ATP binding" "Cluster 54: Non-specific - Ribosome" "Cluster 45: Non-specific - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 15: Non-specific - Protein processing" 35 Cytosol "Focal adhesion sites" "HPA041522: , HPA049430: , HPA067411: " "potential prognostic unfavorable (2.96e-4)" "unprognostic (1.34e-1)" "unprognostic (1.60e-1)" "unprognostic (1.82e-1)" "unprognostic (8.16e-2)" "unprognostic (2.92e-1)" "unprognostic (6.42e-2)" "unprognostic (1.43e-3)" "potential prognostic unfavorable (9.18e-5)" "unprognostic (2.84e-1)" "potential prognostic favorable (5.03e-5)" "unprognostic (2.81e-1)" "unprognostic (7.70e-2)" "potential prognostic unfavorable (5.32e-5)" "unprognostic (3.42e-3)" "unprognostic (1.05e-2)" "unprognostic (3.65e-3)" "unprognostic (2.65e-1)" "unprognostic (4.48e-3)" "unprognostic (2.20e-2)" "unprognostic (1.36e-1)" "potential prognostic unfavorable (8.05e-4)" "unprognostic (1.06e-1)" "unprognostic (1.04e-1)" "unprognostic (1.11e-2)" "unprognostic (3.34e-1)" "unprognostic (2.47e-1)" "unprognostic (4.80e-2)" "unprognostic (4.18e-2)" "unprognostic (3.84e-1)" "unprognostic (8.21e-3)" NOBOX "OG2, Og2x" ENSG00000106410 "NOBOX oogenesis homeobox" O60393 7 144397240-144410227 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Oogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant, Premature ovarian failure" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Loop of henle epithelial cells: 2.2;Neuroendocrine cells: 1.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Head and Neck Squamous Cell Carcinoma (TCGA): 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 51: Myeloma - Immunoglobulins" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" "unprognostic (4.39e-1)" NOC2L "DKFZP564C186, NET15, NET7, NIR, PPP1R112" ENSG00000188976 "NOC2 like nucleolar associated transcriptional repressor" Q9Y3T9 1 944203-959309 "Essential proteins, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044258, HPA062195" Approved Enhanced "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No 91000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 24: Non-specific - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 37: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 59 "Nucleoli, Nucleoli rim, Mitotic chromosome" "HPA044258: , HPA062195: " "unprognostic (1.07e-3)" "unprognostic (1.24e-1)" "unprognostic (1.54e-1)" "unprognostic (4.41e-2)" "unprognostic (1.80e-2)" "unprognostic (1.61e-1)" "unprognostic (9.16e-2)" "unprognostic (4.01e-3)" "unprognostic (2.60e-3)" "unprognostic (2.01e-2)" "potential prognostic favorable (5.32e-4)" "unprognostic (3.38e-1)" "unprognostic (1.10e-1)" "unprognostic (6.83e-3)" "potential prognostic unfavorable (5.01e-5)" "unprognostic (5.23e-2)" "unprognostic (4.87e-3)" "unprognostic (2.01e-1)" "unprognostic (2.16e-1)" "unprognostic (1.61e-1)" "unprognostic (6.84e-2)" "unprognostic (2.11e-1)" "unprognostic (2.14e-1)" "unprognostic (2.85e-1)" "unprognostic (1.11e-1)" "unprognostic (3.88e-3)" "unprognostic (4.46e-2)" "unprognostic (1.20e-1)" "unprognostic (8.53e-2)" "unprognostic (2.35e-2)" "unprognostic (2.44e-1)" NOC3L "AD24, C10orf117, FAD24, FLJ12820" ENSG00000173145 "NOC3 like DNA replication regulator" Q8WTT2 10 94333226-94362959 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 103.0;Epicardial cells: 109.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063958, HPA067638, HPA070981" Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 17: Non-specific - RNA processing" 69 "Nucleoli, Nucleoli rim" Nucleoplasm "HPA063958: , HPA067638: , HPA070981: " "unprognostic (3.15e-1)" "unprognostic (6.50e-2)" "unprognostic (1.64e-1)" "unprognostic (1.39e-1)" "unprognostic (2.44e-1)" "unprognostic (1.45e-1)" "unprognostic (1.41e-2)" "potential prognostic favorable (2.89e-4)" "unprognostic (9.36e-2)" "unprognostic (3.47e-2)" "potential prognostic favorable (3.84e-5)" "unprognostic (1.22e-2)" "unprognostic (1.80e-2)" "unprognostic (3.85e-3)" "unprognostic (1.33e-2)" "unprognostic (1.12e-3)" "unprognostic (2.40e-2)" "unprognostic (3.44e-2)" "unprognostic (1.64e-1)" "unprognostic (1.68e-1)" "potential prognostic unfavorable (9.18e-4)" "unprognostic (9.96e-3)" "unprognostic (2.94e-3)" "unprognostic (3.72e-2)" "unprognostic (6.35e-3)" "unprognostic (1.67e-2)" "unprognostic (1.02e-1)" "unprognostic (7.00e-2)" "unprognostic (3.52e-1)" "unprognostic (4.48e-2)" "unprognostic (4.32e-1)" NOC4L "MGC3162, NET49, Noc4, UTP19" ENSG00000184967 "Nucleolar complex associated 4 homolog" Q9BVI4 12 132144457-132152473 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 72.9;Late primary spermatocytes: 54.5;Late spermatids: 106.8;Oocytes: 73.7;Undifferentiated spermatogonia: 99.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053424 Supported Nucleoplasm,Nucleoli No No "Cluster 13: Non-specific - Mitochondria" "Cluster 24: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 38: Non-specific - Transcription" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 44 Nucleoli Nucleoplasm "HPA053424: " "unprognostic (1.27e-3)" "unprognostic (2.83e-2)" "unprognostic (1.01e-1)" "unprognostic (4.19e-2)" "unprognostic (3.82e-1)" "unprognostic (7.26e-2)" "unprognostic (7.10e-2)" "unprognostic (1.92e-2)" "unprognostic (5.41e-2)" "unprognostic (1.17e-1)" "unprognostic (1.90e-1)" "unprognostic (7.24e-2)" "unprognostic (5.73e-2)" "unprognostic (5.72e-3)" "unprognostic (1.18e-1)" "unprognostic (3.83e-3)" "unprognostic (2.35e-1)" "unprognostic (2.26e-1)" "unprognostic (2.60e-2)" "unprognostic (2.05e-1)" "unprognostic (2.46e-1)" "unprognostic (4.49e-2)" "unprognostic (1.69e-1)" "unprognostic (1.08e-1)" "unprognostic (8.24e-2)" "unprognostic (2.01e-1)" "unprognostic (2.09e-1)" "unprognostic (3.70e-2)" "unprognostic (5.76e-2)" "unprognostic (1.54e-1)" "unprognostic (1.15e-1)" NOCT "Ccr4c, CCR4L, CCRN4L, NOC" ENSG00000151014 Nocturnin Q9UK39 4 139015781-139045939 "Enzymes, Predicted intracellular proteins" "Biological rhythms" "Hydrolase, Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 34.3" "Cell type enhanced" "Detected in many" "Epicardial cells: 206.9;Monocyte progenitors: 165.2;monocytes: 266.4;Neutrophil progenitors: 236.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Kidney - Proximal tubular cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012287, HPA053714" Uncertain Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 29: Forebrain - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 5 "Nuclear bodies" "Nucleoplasm, Cytosol" "HPA012287: , HPA053714: " "unprognostic (1.77e-2)" "unprognostic (1.19e-1)" "potential prognostic unfavorable (2.93e-4)" "unprognostic (1.60e-2)" "unprognostic (1.50e-1)" "unprognostic (3.25e-3)" "unprognostic (5.50e-2)" "potential prognostic unfavorable (4.33e-4)" "unprognostic (4.10e-2)" "unprognostic (1.17e-1)" "unprognostic (3.87e-2)" "unprognostic (3.74e-2)" "unprognostic (2.51e-1)" "unprognostic (4.71e-2)" "potential prognostic unfavorable (8.44e-4)" "unprognostic (5.67e-3)" "unprognostic (6.30e-2)" "unprognostic (2.03e-2)" "unprognostic (8.08e-2)" "unprognostic (7.56e-2)" "potential prognostic unfavorable (5.83e-4)" "potential prognostic unfavorable (6.25e-4)" "unprognostic (1.38e-1)" "unprognostic (1.17e-1)" "unprognostic (2.27e-1)" "unprognostic (1.29e-1)" "unprognostic (2.33e-1)" "potential prognostic unfavorable (8.40e-4)" "unprognostic (2.02e-1)" NOD1 "CARD4, CLR7.1, NLRC1" ENSG00000106100 "Nucleotide binding oligomerization domain containing 1" Q9Y239 7 30424527-30478784 "Human disease related genes, Predicted intracellular proteins" "Apoptosis, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 88.8;Lymphatic endothelial cells: 88.7;Pituicytes/FSCs: 221.8;Schwann cells: 105.8;Transitional alveolar cells: 96.6;Vascular endothelial cells: 94.9" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 71.5;endothelial cell: 151.9" "Cancer enhanced" "Detected in all" "Thyroid Carcinoma (TCGA): 28.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" HPA074367 Approved Mitochondria NA NA "Cluster 32: Basophils - Transcription" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 67: Non-specific - Unknown function" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 21 Mitochondria "HPA074367: " "unprognostic (3.71e-2)" "unprognostic (3.81e-1)" "unprognostic (1.91e-3)" "potential prognostic unfavorable (5.99e-5)" "unprognostic (9.19e-3)" "unprognostic (1.58e-1)" "unprognostic (2.72e-2)" "unprognostic (1.13e-1)" "unprognostic (1.13e-1)" "unprognostic (1.49e-1)" "unprognostic (2.20e-3)" "unprognostic (4.10e-3)" "unprognostic (8.35e-2)" "unprognostic (1.28e-3)" "unprognostic (1.29e-1)" "unprognostic (5.51e-3)" "unprognostic (1.82e-2)" "unprognostic (1.09e-2)" "unprognostic (3.25e-1)" "unprognostic (1.72e-1)" "unprognostic (1.92e-1)" "unprognostic (1.53e-1)" "unprognostic (2.68e-2)" "unprognostic (2.38e-1)" "unprognostic (7.39e-3)" "unprognostic (5.57e-2)" "unprognostic (1.41e-1)" "unprognostic (8.75e-2)" "unprognostic (3.46e-1)" "unprognostic (1.73e-3)" "unprognostic (1.17e-2)" NOD2 "BLAU, CARD15, CD, CLR16.3, IBD1, NLRC2, PSORAS1" ENSG00000167207 "Nucleotide binding oligomerization domain containing 2" Q9HC29 16 50693588-50733077 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "Adaptive immunity, Autophagy, Immunity, Innate immunity" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.0;esophagus: 9.5;skin 1: 12.8;vagina: 10.2" "Cell type enhanced" "Detected in many" "cDC: 35.9;Endometrial luminal cells: 22.8;Esophageal apical cells: 57.1;Esophageal suprabasal cells: 42.0;Macrophages: 19.0;Monocyte progenitors: 28.1;monocytes: 61.3;Neutrophils: 58.2;Suprabasal keratinocytes: 29.6" "Cell type enriched" "Detected in some" 4 "leukocyte: 15.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "classical monocyte: 21.7;eosinophil: 5.6;intermediate monocyte: 12.2;myeloid DC: 20.4;neutrophil: 10.0;non-classical monocyte: 8.4" "Group enriched" "Detected in many" 9 "dendritic cells: 20.4;granulocytes: 10.0;monocytes: 21.7" "Cancer enhanced" "Detected in some" "lymphoma: 5.7" "Adipose visceral - Macrophages, Adrenal gland - Macrophages, Lung - NK-cells (Lung)" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA041985, HPA054494" Enhanced Supported "Golgi apparatus,Cytosol" No NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 44: Non-specific - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 69 "Golgi apparatus, Cytosol" "HPA041985: , HPA054494: " "unprognostic (5.48e-3)" "unprognostic (1.53e-1)" "unprognostic (2.59e-1)" "unprognostic (2.55e-1)" "unprognostic (1.79e-1)" "unprognostic (2.87e-1)" "unprognostic (3.42e-3)" "unprognostic (3.49e-1)" "unprognostic (6.89e-2)" "potential prognostic unfavorable (7.23e-4)" "unprognostic (1.09e-3)" "unprognostic (7.31e-3)" "unprognostic (8.10e-2)" "unprognostic (1.44e-2)" "unprognostic (1.86e-2)" "unprognostic (5.50e-2)" "unprognostic (1.66e-1)" "unprognostic (4.01e-2)" "unprognostic (7.01e-3)" "unprognostic (3.35e-3)" "unprognostic (5.06e-2)" "unprognostic (4.19e-2)" "unprognostic (1.53e-1)" "unprognostic (2.81e-3)" "unprognostic (1.09e-3)" "unprognostic (2.55e-1)" NODAL ENSG00000156574 "Nodal growth differentiation factor" Q96S42 10 70431936-70447951 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cytokine, Developmental protein, Growth factor" "Disease variant, Heterotaxy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skeletal muscle: 2.6" "Cell type enhanced" "Detected in some" "Early spermatids: 24.9;Epicardial cells: 15.9;Late spermatids: 59.9;Myonuclei: 8.8" "Cell type enriched" "Detected in some" 6 "pericyte: 25.9" "Cancer enriched" "Detected in some" 9 "Testicular Germ Cell Tumor (TCGA): 47.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "testis cancer: 3.2" "Testis - Late spermatids" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 2.0" HPA045201 Uncertain "Secreted to blood" Cytokine NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 15: Non-specific - Transcription" "Cluster 32: Non-specific - Cell proliferation" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 2 "HPA045201: " "unprognostic (3.23e-1)" "unprognostic (1.05e-1)" "unprognostic (3.51e-1)" "unprognostic (3.39e-1)" "unprognostic (2.88e-1)" "unprognostic (1.93e-1)" "unprognostic (7.31e-2)" NOG "SYM1, SYNS1" ENSG00000183691 Noggin Q13253 17 56593699-56595611 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Chondrogenesis, Differentiation" "Developmental protein" "Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.5;placenta: 10.0" "Group enriched" "Detected in some" 9 "Extravillous trophoblasts: 25.9;Retinal pigment epithelial cells: 98.0" "Cell type enhanced" "Detected in many" "Bergmann glia: 10.3;LAMP5-LHX6 and Chandelier: 15.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "naive CD4 T-cell: 73.0;naive CD8 T-cell: 35.0" "Lineage enriched" "Detected in single" 78 "T-cells: 73.0" "Cancer enhanced" "Detected in many" "Rhabdoid: 27.0" "Adipose subcutaneous - Smooth muscle cells, Prostate - Smooth muscle cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061318 Approved "Secreted to blood" "Developmental protein" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" 7 "HPA061318: " "unprognostic (5.11e-2)" "unprognostic (2.45e-1)" "unprognostic (4.60e-2)" "unprognostic (3.72e-3)" "unprognostic (6.37e-3)" "unprognostic (2.73e-1)" "unprognostic (3.06e-2)" "unprognostic (1.04e-1)" "potential prognostic unfavorable (3.00e-4)" "unprognostic (1.88e-2)" "unprognostic (6.97e-2)" "unprognostic (6.29e-3)" NOL10 "FLJ14075, PQBP5" ENSG00000115761 "Nucleolar protein 10" Q9BSC4 2 10562347-10689987 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035286, HPA043075" Approved Supported Nucleoli NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 24: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 17: Non-specific - RNA processing" 10 Nucleoli "HPA035286: , HPA043075: " "unprognostic (2.32e-1)" "unprognostic (3.07e-3)" "unprognostic (2.47e-1)" "unprognostic (1.19e-2)" "unprognostic (4.35e-1)" "unprognostic (4.86e-3)" "unprognostic (1.35e-1)" "unprognostic (5.60e-2)" "unprognostic (1.47e-2)" "potential prognostic unfavorable (9.74e-4)" "unprognostic (3.99e-3)" "unprognostic (5.68e-2)" "potential prognostic unfavorable (6.05e-4)" "validated prognostic unfavorable (2.63e-7)" "validated prognostic unfavorable (3.53e-7)" "potential prognostic unfavorable (3.93e-4)" "unprognostic (1.15e-2)" "unprognostic (4.21e-3)" "unprognostic (2.94e-1)" "unprognostic (2.07e-1)" "unprognostic (6.50e-2)" "unprognostic (4.22e-3)" "potential prognostic unfavorable (9.63e-4)" "unprognostic (2.94e-3)" "unprognostic (2.15e-1)" "unprognostic (3.68e-2)" "unprognostic (5.17e-2)" "unprognostic (2.32e-1)" "unprognostic (2.56e-1)" "unprognostic (1.58e-1)" "unprognostic (1.37e-1)" NOL11 DKFZP586L0724 ENSG00000130935 "Nucleolar protein 11" Q9H8H0 17 67717931-67744531 "Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022010 Supported Supported Nucleoli NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 17: Non-specific - RNA processing" 34 Nucleoli "HPA022010: " "unprognostic (2.48e-1)" "unprognostic (4.92e-2)" "unprognostic (7.72e-2)" "unprognostic (7.72e-3)" "unprognostic (2.33e-2)" "unprognostic (1.44e-1)" "unprognostic (1.68e-2)" "unprognostic (1.15e-2)" "unprognostic (1.94e-1)" "unprognostic (1.28e-2)" "potential prognostic favorable (1.43e-5)" "unprognostic (1.02e-1)" "unprognostic (1.33e-1)" "unprognostic (1.41e-2)" "potential prognostic unfavorable (3.89e-4)" "unprognostic (2.57e-2)" "potential prognostic unfavorable (1.44e-6)" "unprognostic (3.13e-1)" "unprognostic (1.14e-2)" "unprognostic (8.88e-2)" "unprognostic (1.59e-1)" "unprognostic (2.87e-1)" "unprognostic (7.41e-3)" "unprognostic (4.51e-2)" "potential prognostic favorable (3.59e-4)" "unprognostic (5.28e-2)" "unprognostic (2.10e-2)" "unprognostic (1.90e-1)" "unprognostic (1.96e-1)" "unprognostic (1.51e-2)" "unprognostic (1.36e-1)" NOL12 "MGC3731, Nop25, RRP17" ENSG00000273899 "Nucleolar protein 12" Q9UGY1 22 37681673-37693476 "Essential proteins, Predicted intracellular proteins" "RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 14.9;Brain inhibitory neurons: 13.6;Colonocytes: 17.3;Early spermatids: 50.2;Enteric transient amplifying cells: 14.5;Enterocytes: 15.6;Goblet cells: 13.9;Late primary spermatocytes: 35.7;Late spermatids: 14.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003547 Uncertain Approved "Nucleoplasm,Nucleoli,Mitotic chromosome,Vesicles" Yes No "Cluster 25: Non-specific - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 15: Non-specific - Protein processing" 42 "Nucleoli, Mitotic chromosome" "Nucleoplasm, Vesicles" "HPA003547: " "unprognostic (5.26e-2)" "unprognostic (1.30e-1)" "unprognostic (1.57e-1)" "unprognostic (2.10e-2)" "unprognostic (2.82e-2)" "unprognostic (1.21e-1)" "unprognostic (3.14e-1)" "unprognostic (2.10e-1)" "unprognostic (1.41e-3)" "unprognostic (8.57e-3)" "unprognostic (1.67e-2)" "unprognostic (2.07e-2)" "potential prognostic unfavorable (2.22e-5)" "unprognostic (6.16e-2)" "unprognostic (2.29e-1)" "unprognostic (1.31e-3)" "unprognostic (1.16e-2)" "unprognostic (1.15e-2)" "unprognostic (1.22e-2)" "unprognostic (6.08e-3)" "unprognostic (2.72e-1)" "unprognostic (9.51e-2)" "unprognostic (8.67e-3)" "unprognostic (2.09e-1)" "unprognostic (3.68e-2)" "unprognostic (3.40e-3)" "unprognostic (6.63e-2)" "unprognostic (2.12e-1)" NOL3 "ARC, CARD2, MYP, NOP30" ENSG00000140939 "Nucleolar protein 3" O60936 16 67170154-67175737 "Disease related genes, Predicted intracellular proteins" "Apoptosis, mRNA processing, mRNA splicing" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 329.0;Esophageal suprabasal cells: 108.6;Myonuclei: 115.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 3.4" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" CAB009208 Enhanced Supported Nucleoplasm,Cytosol NA NA 9700 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 24: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 62: Smooth muscle cells - Muscle contraction" 9 "Nucleoplasm, Cytosol" "CAB009208: " "unprognostic (2.66e-1)" "potential prognostic unfavorable (9.43e-4)" "unprognostic (7.96e-2)" "unprognostic (8.56e-3)" "unprognostic (1.26e-2)" "unprognostic (1.09e-1)" "validated prognostic unfavorable (8.58e-5)" "validated prognostic unfavorable (5.09e-4)" "unprognostic (6.14e-2)" "unprognostic (5.44e-2)" "unprognostic (5.71e-2)" "unprognostic (4.48e-1)" "unprognostic (2.07e-1)" "potential prognostic unfavorable (5.00e-4)" "unprognostic (8.86e-2)" "unprognostic (1.88e-1)" "unprognostic (2.47e-1)" "unprognostic (2.04e-2)" "unprognostic (2.09e-1)" "unprognostic (1.22e-1)" "unprognostic (4.52e-2)" "unprognostic (2.01e-1)" "potential prognostic unfavorable (3.87e-4)" "unprognostic (1.27e-2)" "unprognostic (8.52e-2)" "unprognostic (6.15e-2)" "unprognostic (1.03e-2)" "unprognostic (6.14e-3)" "unprognostic (3.80e-1)" "unprognostic (9.57e-2)" "unprognostic (1.42e-2)" NOL4 "CT125, HRIHFB2255, NOLP" ENSG00000101746 "Nucleolar protein 4" O94818 18 33851100-34224952 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.6;pituitary gland: 6.3;retina: 5.8;testis: 11.7" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 191.5;Bergmann glia: 210.9;Brain excitatory neurons: 225.4;Brain inhibitory neurons: 256.0;Corticotrophs: 1001.4;Early spermatids: 389.7;Gonadotrophs: 252.9;Lactotrophs: 567.9;Late primary spermatocytes: 279.7;Oligodendrocyte progenitor cells: 454.9;Other brain neurons: 250.5;Pancreatic islet cells: 397.4;Somatotrophs: 523.0;Thyrotrophs: 493.2" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Glioblastoma Multiforme (TCGA): 4.2;Kidney Renal Papillary Cell Carcinoma (TCGA): 2.4;Pancreatic Adenocarcinoma (TCGA): 1.9;Prostate Adenocarcinoma (TCGA): 1.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 8.6;Neuroblastoma: 7.7" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Adrenal gland - Adrenal medulla cells, Breast - Breast myoepithelial cells, Liver - Hepatocytes, Minor Salivary Gland - Smooth muscle cells, Pancreas - Alpha cells, Pancreas - Beta cells, Stomach - Gastric enteroendocrine cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046740 Supported Nucleoplasm No NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 5 Nucleoplasm "HPA046740: " "unprognostic (7.93e-2)" "unprognostic (3.52e-1)" "potential prognostic favorable (1.77e-4)" "unprognostic (1.59e-2)" "unprognostic (2.42e-2)" "unprognostic (1.16e-2)" "unprognostic (1.69e-2)" "unprognostic (7.41e-2)" NOL4L "C20orf112, C20orf113, dJ1184F4.2, dJ1184F4.4, DKFZP566G1424" ENSG00000197183 "Nucleolar protein 4 like" Q96MY1 20 32443059-32585333 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 45.9" "Cell type enhanced" "Detected in many" "Corticotrophs: 217.2;Late primary spermatocytes: 181.7;Late spermatids: 203.3;Megakaryocyte progenitors: 141.9;Megakaryocyte-Erythroid progenitors: 155.9;Oocytes: 156.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Gastric mucous cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041768, HPA043600" Enhanced Enhanced Nucleoplasm NA Yes "Cluster 33: Non-specific - ATP binding" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 47: Leukemia - Hemostasis" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 5 Nucleoplasm "HPA041768: , HPA043600: " "unprognostic (1.62e-2)" "unprognostic (1.36e-1)" "unprognostic (9.19e-2)" "unprognostic (1.90e-1)" "unprognostic (3.35e-1)" "unprognostic (1.05e-1)" "unprognostic (5.24e-2)" "unprognostic (2.17e-2)" "unprognostic (1.29e-1)" "unprognostic (1.10e-1)" "unprognostic (5.09e-3)" "unprognostic (1.19e-1)" "unprognostic (2.38e-3)" "unprognostic (2.61e-1)" "unprognostic (1.40e-1)" "unprognostic (4.17e-3)" "unprognostic (6.38e-2)" "unprognostic (4.20e-2)" "unprognostic (1.71e-1)" "unprognostic (5.28e-2)" "unprognostic (3.02e-2)" "unprognostic (5.19e-2)" "unprognostic (1.06e-2)" "unprognostic (5.14e-2)" "unprognostic (1.71e-1)" "unprognostic (1.48e-1)" "unprognostic (2.02e-1)" "unprognostic (1.02e-1)" "unprognostic (7.71e-2)" NOL6 "bA311H10.1, FLJ21959, MGC14896, MGC14921, MGC20838, Nrap, UTP22" ENSG00000165271 "Nucleolar protein 6" Q9H6R4 9 33461353-33473930 "Essential proteins, Predicted intracellular proteins, Predicted membrane proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 37.3;Late spermatids: 30.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055891, HPA061002" Supported Enhanced Nucleoplasm,Nucleoli NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 24: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 17: Non-specific - RNA processing" 13 Nucleoli Nucleoplasm "HPA055891: , HPA061002: " "unprognostic (1.93e-1)" "unprognostic (1.60e-2)" "unprognostic (3.26e-1)" "unprognostic (1.91e-1)" "unprognostic (2.55e-1)" "unprognostic (2.78e-2)" "unprognostic (3.32e-1)" "unprognostic (3.70e-2)" "unprognostic (9.10e-2)" "unprognostic (1.27e-1)" "unprognostic (1.62e-2)" "unprognostic (6.96e-2)" "unprognostic (3.33e-1)" "potential prognostic unfavorable (1.76e-9)" "unprognostic (1.43e-2)" "unprognostic (3.87e-2)" "unprognostic (4.34e-2)" "unprognostic (1.01e-1)" "unprognostic (9.30e-2)" "unprognostic (3.12e-2)" "unprognostic (5.79e-3)" "unprognostic (2.15e-1)" "unprognostic (3.86e-1)" "unprognostic (2.22e-2)" "unprognostic (2.38e-2)" "unprognostic (1.77e-1)" "unprognostic (2.29e-2)" "unprognostic (1.30e-2)" "unprognostic (1.20e-1)" "unprognostic (1.47e-2)" "unprognostic (1.20e-2)" NOL7 "C6orf90, dJ223E5.2, NOP27, PQBP3, RARG-1" ENSG00000225921 "Nucleolar protein 7" Q9UMY1 6 13615335-13632739 "Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029185 Supported Supported "Nucleoli,Mitotic chromosome,Mitochondria" Yes Yes "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 20 "Nucleoli, Mitotic chromosome" Mitochondria "HPA029185: " "unprognostic (2.46e-1)" "unprognostic (5.62e-2)" "unprognostic (1.34e-1)" "unprognostic (5.98e-2)" "unprognostic (1.12e-1)" "unprognostic (1.56e-1)" "unprognostic (1.43e-1)" "unprognostic (4.28e-2)" "unprognostic (1.72e-1)" "potential prognostic unfavorable (2.09e-4)" "validated prognostic favorable (7.78e-6)" "validated prognostic favorable (6.90e-5)" "unprognostic (7.90e-3)" "unprognostic (2.76e-3)" "potential prognostic unfavorable (1.60e-6)" "unprognostic (2.66e-1)" "unprognostic (6.46e-2)" "unprognostic (3.24e-1)" "unprognostic (2.35e-3)" "potential prognostic favorable (1.22e-5)" "unprognostic (4.11e-2)" "unprognostic (1.51e-1)" "unprognostic (1.14e-1)" "unprognostic (2.96e-2)" "unprognostic (8.64e-3)" "unprognostic (2.15e-1)" "unprognostic (3.03e-1)" "unprognostic (2.42e-1)" "unprognostic (1.51e-1)" "unprognostic (2.23e-1)" "unprognostic (1.39e-1)" NOL8 "C9orf34, FLJ20736, Nop132" ENSG00000198000 "Nucleolar protein 8" Q76FK4 9 92297358-92325636 "Essential proteins, Predicted intracellular proteins" "rRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Megakaryocyte-Erythroid progenitors: 113.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044440, HPA062922" Uncertain Supported "Nucleoli,Mitotic chromosome" Yes No "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 17: Non-specific - RNA processing" 9 Nucleoli "Mitotic chromosome" "HPA044440: , HPA062922: " "unprognostic (5.31e-2)" "unprognostic (5.26e-2)" "unprognostic (2.64e-2)" "unprognostic (1.60e-1)" "unprognostic (4.23e-1)" "unprognostic (3.27e-1)" "unprognostic (2.36e-1)" "unprognostic (7.77e-2)" "unprognostic (4.30e-2)" "unprognostic (6.66e-3)" "potential prognostic favorable (5.33e-6)" "unprognostic (5.09e-2)" "unprognostic (1.06e-1)" "unprognostic (7.89e-2)" "unprognostic (2.19e-1)" "unprognostic (8.96e-2)" "unprognostic (5.36e-3)" "unprognostic (6.97e-2)" "unprognostic (2.89e-1)" "unprognostic (1.66e-1)" "unprognostic (8.22e-2)" "unprognostic (1.17e-1)" "unprognostic (4.67e-2)" "unprognostic (5.32e-3)" "unprognostic (2.74e-2)" "unprognostic (1.69e-1)" "unprognostic (2.98e-2)" "unprognostic (3.07e-1)" "unprognostic (7.61e-2)" "unprognostic (1.31e-1)" "unprognostic (4.77e-2)" NOL9 "FLJ23323, Grc3, NET6" ENSG00000162408 "Nucleolar protein 9" Q5SY16 1 6521347-6554513 "Essential proteins, Metabolic proteins, Predicted intracellular proteins" "rRNA processing" "Kinase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036347 Supported "Nucleoli,Intermediate filaments" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 64: Non-specific - Transcription" "Cluster 29: Forebrain - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 39 Nucleoli "Intermediate filaments" "HPA036347: " "unprognostic (8.97e-2)" "unprognostic (5.13e-2)" "unprognostic (7.81e-2)" "unprognostic (4.14e-2)" "unprognostic (8.43e-2)" "unprognostic (1.74e-1)" "unprognostic (2.88e-1)" "unprognostic (1.37e-3)" "unprognostic (2.09e-1)" "unprognostic (4.51e-2)" "unprognostic (4.86e-2)" "unprognostic (2.88e-3)" "unprognostic (4.25e-3)" "potential prognostic unfavorable (4.09e-8)" "unprognostic (2.06e-3)" "unprognostic (2.11e-1)" "unprognostic (5.39e-2)" "unprognostic (5.98e-2)" "potential prognostic favorable (6.81e-4)" "unprognostic (1.06e-1)" "unprognostic (4.36e-2)" "unprognostic (3.98e-3)" "unprognostic (8.83e-2)" "unprognostic (2.23e-1)" "unprognostic (1.18e-1)" "potential prognostic favorable (9.63e-4)" "unprognostic (1.07e-1)" "unprognostic (1.44e-2)" "unprognostic (3.03e-1)" "unprognostic (5.85e-2)" "unprognostic (2.00e-1)" NOLC1 "KIAA0035, NOPP130, NOPP140, P130, Srp40" ENSG00000166197 "Nucleolar and coiled-body phosphoprotein 1" Q14978 10 102152176-102163871 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032654, HPA037366, HPA050388" Supported Enhanced "Nucleoli fibrillar center" No Yes 8700 "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 17: Non-specific - RNA processing" 49 "Nucleoli fibrillar center" "CAB032654: , HPA037366: , HPA050388: " "unprognostic (9.00e-2)" "unprognostic (1.29e-1)" "unprognostic (1.30e-1)" "unprognostic (1.85e-2)" "unprognostic (2.33e-1)" "unprognostic (2.08e-1)" "unprognostic (3.06e-2)" "unprognostic (3.97e-3)" "unprognostic (6.05e-2)" "unprognostic (4.65e-3)" "potential prognostic favorable (9.91e-6)" "unprognostic (2.82e-2)" "unprognostic (2.86e-2)" "unprognostic (7.32e-2)" "unprognostic (2.31e-3)" "unprognostic (5.55e-3)" "potential prognostic unfavorable (1.33e-4)" "unprognostic (3.51e-1)" "unprognostic (9.42e-2)" "unprognostic (1.95e-1)" "unprognostic (2.43e-1)" "potential prognostic unfavorable (3.63e-5)" "unprognostic (7.86e-2)" "unprognostic (2.76e-2)" "unprognostic (1.91e-3)" "unprognostic (4.29e-2)" "unprognostic (3.61e-1)" "unprognostic (7.00e-2)" "unprognostic (2.99e-1)" "unprognostic (1.70e-2)" "unprognostic (1.26e-1)" NOM1 "C7orf3, PPP1R113, SGD1" ENSG00000146909 "Nucleolar protein with MIF4G domain 1" Q5C9Z4 7 156949712-156973176 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019866, HPA051624" Approved Enhanced Nucleoli NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 53 Nucleoli "HPA019866: , HPA051624: " "unprognostic (1.60e-2)" "unprognostic (5.26e-2)" "unprognostic (2.46e-1)" "unprognostic (1.21e-3)" "unprognostic (3.06e-1)" "unprognostic (3.40e-1)" "unprognostic (3.84e-1)" "unprognostic (3.17e-2)" "unprognostic (2.14e-1)" "unprognostic (6.62e-3)" "unprognostic (6.85e-2)" "unprognostic (5.24e-2)" "unprognostic (4.51e-2)" "unprognostic (7.38e-2)" "unprognostic (2.12e-3)" "unprognostic (1.23e-1)" "unprognostic (2.03e-3)" "unprognostic (1.80e-1)" "unprognostic (1.60e-1)" "unprognostic (2.60e-1)" "unprognostic (7.85e-2)" "unprognostic (6.12e-2)" "unprognostic (5.47e-3)" "unprognostic (2.53e-2)" "unprognostic (3.61e-2)" "unprognostic (4.83e-1)" "unprognostic (2.16e-2)" "unprognostic (2.86e-2)" "unprognostic (3.57e-1)" "unprognostic (5.64e-3)" "unprognostic (2.51e-2)" NOMO1 PM5 ENSG00000103512 "NODAL modulator 1" Q15155 16 14833721-14896157 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 132.5" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 21.3;Brain inhibitory neurons: 14.5;Distal convoluted tubule cells: 18.6;Loop of henle epithelial cells: 17.8;Oligodendrocyte progenitor cells: 16.5;Oligodendrocytes: 33.4;Other brain neurons: 14.3;Platelets: 29.5;Renal connecting tubule cells: 14.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "hypothalamus: 14.0" "Immune cell enhanced" "Detected in some" "basophil: 3.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Pituitary gland - Thyrotropes, Testis - Spermatocytes, Testis - Spermatogonia" "CAB025192, HPA046697, HPA061174" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 24: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" 57 "Endoplasmic reticulum" "CAB025192: , HPA046697: , HPA061174: " "unprognostic (3.59e-2)" "unprognostic (2.07e-2)" "unprognostic (3.05e-3)" "unprognostic (4.02e-2)" "unprognostic (3.06e-1)" "unprognostic (2.16e-2)" "unprognostic (3.20e-1)" "unprognostic (7.64e-2)" "unprognostic (1.34e-1)" "potential prognostic unfavorable (9.94e-4)" "unprognostic (2.19e-2)" "unprognostic (3.08e-1)" "unprognostic (1.39e-1)" "unprognostic (1.00e-1)" "potential prognostic unfavorable (3.63e-4)" "unprognostic (1.13e-1)" "unprognostic (6.67e-2)" "unprognostic (1.58e-1)" "unprognostic (8.63e-3)" "unprognostic (1.15e-1)" "unprognostic (1.84e-3)" "unprognostic (2.71e-2)" "unprognostic (1.75e-1)" "unprognostic (3.73e-1)" "unprognostic (3.30e-2)" "unprognostic (1.39e-2)" "unprognostic (4.40e-2)" "unprognostic (1.01e-2)" "unprognostic (1.05e-1)" "unprognostic (2.20e-2)" "unprognostic (3.07e-2)" NOMO2 "NOMO, PM5" ENSG00000185164 "NODAL modulator 2" Q5JPE7 16 18417325-18562211 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "HPA046697, HPA061174" Approved NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 70: Non-specific - Protein processing" "Cluster 14: Neurons - Synaptic function" "Cluster 63: Non-specific - Protein processing" "Cluster 67: Plasma cells - Plasma cell differentiation" 3 "HPA046697: , HPA061174: " "unprognostic (2.34e-3)" "unprognostic (4.08e-3)" "unprognostic (1.31e-1)" "unprognostic (2.52e-3)" "unprognostic (1.36e-1)" "unprognostic (6.93e-2)" "unprognostic (9.74e-2)" "unprognostic (1.13e-1)" "potential prognostic unfavorable (3.48e-4)" "unprognostic (1.66e-1)" "validated prognostic unfavorable (1.26e-5)" "validated prognostic unfavorable (3.77e-6)" "unprognostic (1.73e-2)" "unprognostic (1.10e-1)" "unprognostic (2.48e-2)" "unprognostic (7.89e-2)" "unprognostic (4.66e-3)" "unprognostic (8.47e-2)" "unprognostic (1.49e-1)" "unprognostic (2.45e-2)" "unprognostic (1.29e-3)" "unprognostic (1.95e-1)" "unprognostic (4.82e-2)" "unprognostic (1.54e-1)" "unprognostic (3.85e-2)" "unprognostic (1.36e-1)" "unprognostic (4.21e-2)" "unprognostic (2.91e-1)" "unprognostic (3.37e-1)" "unprognostic (1.27e-1)" "unprognostic (5.11e-2)" NOMO3 ENSG00000103226 "NODAL modulator 3" P69849 16 16232506-16300806 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 5.9" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 8.6;Loop of henle epithelial cells: 9.7;Microglia: 10.1;Oligodendrocyte progenitor cells: 10.4;Oligodendrocytes: 15.3;Paneth cells: 7.7;Retinal horizontal cells: 8.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Spermatocytes" "HPA046697, HPA061174" Approved NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 27: Cerebellum - Synaptic function" "Cluster 34: Non-specific - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 98: Neurons - Neurotransmission & signaling" 28 "HPA046697: , HPA061174: " "unprognostic (6.51e-2)" "unprognostic (1.87e-1)" "unprognostic (2.07e-2)" "unprognostic (3.32e-1)" "unprognostic (6.22e-2)" "unprognostic (2.09e-2)" "validated prognostic unfavorable (7.37e-9)" "validated prognostic unfavorable (8.94e-7)" "unprognostic (2.49e-2)" "unprognostic (2.82e-2)" "unprognostic (1.07e-1)" "unprognostic (3.52e-2)" "unprognostic (2.09e-2)" "unprognostic (1.94e-1)" "unprognostic (2.66e-2)" "unprognostic (1.37e-2)" "unprognostic (1.48e-1)" "unprognostic (5.11e-2)" "unprognostic (2.30e-2)" NONO "NMT55, NRB54, P54, P54NRB, PPP1R114" ENSG00000147140 "Non-POU domain containing octamer binding" Q15233 X 71254814-71301522 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, DNA damage, DNA recombination, DNA repair, Immunity, Innate immunity, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor, RNA-binding" "Cancer-related genes, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022069, HPA054094, HPA054559" Enhanced Enhanced "Nucleoplasm,Nucleoli,Nucleoli fibrillar center" NA NA 4300000 "Cluster 13: Non-specific - Mitochondria" "Cluster 54: Non-specific - Ribosome" "Cluster 25: Non-specific - Transcription" "Cluster 36: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 98 Nucleoplasm "Nucleoli, Nucleoli fibrillar center" "CAB022069: , HPA054094: , HPA054559: " "unprognostic (8.33e-2)" "unprognostic (3.48e-3)" "unprognostic (1.90e-1)" "unprognostic (1.08e-2)" "unprognostic (1.34e-1)" "unprognostic (1.56e-1)" "unprognostic (1.41e-1)" "unprognostic (2.67e-3)" "unprognostic (3.82e-2)" "potential prognostic unfavorable (1.15e-4)" "validated prognostic favorable (1.18e-5)" "validated prognostic favorable (7.31e-4)" "potential prognostic unfavorable (1.95e-4)" "validated prognostic unfavorable (3.83e-4)" "validated prognostic unfavorable (2.73e-6)" "unprognostic (9.95e-2)" "potential prognostic unfavorable (5.21e-4)" "unprognostic (5.37e-2)" "unprognostic (5.87e-2)" "unprognostic (3.68e-1)" "unprognostic (7.54e-2)" "unprognostic (2.44e-2)" "unprognostic (1.92e-1)" "unprognostic (5.42e-2)" "unprognostic (3.01e-2)" "unprognostic (8.74e-2)" "unprognostic (9.44e-2)" "unprognostic (1.62e-1)" "unprognostic (1.62e-1)" "unprognostic (1.46e-1)" "unprognostic (2.30e-1)" NOP10 "MGC70651, NOLA3, NOP10P" ENSG00000182117 "NOP10 ribonucleoprotein" Q9NPE3 15 34339159-34343180 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" Ribonucleoprotein "Cataract, Deafness, Disease variant, Dyskeratosis congenita" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 1320.6;Esophageal suprabasal cells: 786.4;Hofbauer cells: 1115.1;Kupffer cells: 548.3;Neutrophils: 683.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059198 Supported Supported "Nuclear bodies" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 58: Non-specific - Nuclear processes" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 37 "Nuclear bodies" "HPA059198: " "unprognostic (1.85e-2)" "unprognostic (2.59e-2)" "unprognostic (1.74e-1)" "unprognostic (2.99e-2)" "unprognostic (6.31e-2)" "unprognostic (1.40e-1)" "unprognostic (1.86e-1)" "unprognostic (1.77e-1)" "unprognostic (1.18e-2)" "unprognostic (2.53e-3)" "unprognostic (2.01e-2)" "unprognostic (2.10e-1)" "unprognostic (9.32e-2)" "validated prognostic unfavorable (4.90e-4)" "validated prognostic unfavorable (2.53e-4)" "unprognostic (2.88e-3)" "unprognostic (1.87e-3)" "unprognostic (3.33e-2)" "unprognostic (9.02e-2)" "unprognostic (2.81e-2)" "unprognostic (2.92e-1)" "potential prognostic unfavorable (7.74e-4)" "unprognostic (1.19e-1)" "unprognostic (1.04e-1)" "unprognostic (1.74e-1)" "unprognostic (1.36e-1)" "unprognostic (2.38e-2)" "unprognostic (1.39e-1)" "unprognostic (1.26e-1)" "unprognostic (2.38e-1)" "unprognostic (4.97e-2)" NOP14 "C4orf9, NOL14, RES4-25, UTP2" ENSG00000087269 "NOP14 nucleolar protein" P78316 4 2937933-2963406 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 106.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039596, HPA055652" Approved Enhanced Nucleoplasm,Nucleoli NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 17: Non-specific - RNA processing" 52 Nucleoli Nucleoplasm "HPA039596: , HPA055652: " "unprognostic (6.80e-3)" "unprognostic (5.44e-3)" "unprognostic (1.51e-2)" "unprognostic (1.51e-3)" "unprognostic (1.65e-2)" "unprognostic (7.32e-2)" "unprognostic (5.37e-2)" "unprognostic (1.61e-1)" "unprognostic (6.46e-2)" "unprognostic (7.76e-3)" "validated prognostic favorable (3.61e-5)" "validated prognostic favorable (2.55e-4)" "unprognostic (1.13e-1)" "unprognostic (5.06e-3)" "potential prognostic unfavorable (1.21e-4)" "unprognostic (3.35e-2)" "potential prognostic unfavorable (7.47e-5)" "unprognostic (1.26e-1)" "unprognostic (9.07e-2)" "unprognostic (2.94e-1)" "unprognostic (1.09e-2)" "unprognostic (1.46e-1)" "unprognostic (1.86e-1)" "unprognostic (2.83e-2)" "unprognostic (2.26e-2)" "unprognostic (8.00e-2)" "unprognostic (1.34e-3)" "unprognostic (4.53e-3)" "unprognostic (5.64e-1)" "unprognostic (3.12e-2)" "unprognostic (6.30e-3)" NOP16 "HSPC111, HSPC185, LOC51491" ENSG00000048162 "NOP16 nucleolar protein" Q9Y3C1 5 176383946-176388927 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 155.5;Cardiomyocytes: 86.7;Esophageal basal cells: 235.1;Esophageal suprabasal cells: 143.8;Suprabasal keratinocytes: 164.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036506, HPA058147" Approved Enhanced Nucleoli NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 17: Non-specific - RNA processing" 69 Nucleoli "HPA036506: , HPA058147: " "unprognostic (2.69e-2)" "unprognostic (1.06e-1)" "unprognostic (2.13e-1)" "unprognostic (3.73e-2)" "unprognostic (8.75e-2)" "unprognostic (4.07e-2)" "unprognostic (3.87e-2)" "unprognostic (8.58e-2)" "unprognostic (4.53e-2)" "potential prognostic unfavorable (9.23e-5)" "unprognostic (1.23e-1)" "unprognostic (4.41e-3)" "unprognostic (1.26e-3)" "validated prognostic unfavorable (3.41e-4)" "validated prognostic unfavorable (3.12e-4)" "validated prognostic unfavorable (5.86e-4)" "validated prognostic unfavorable (7.50e-4)" "unprognostic (2.05e-1)" "unprognostic (3.39e-2)" "unprognostic (7.32e-3)" "unprognostic (1.20e-1)" "unprognostic (2.57e-2)" "unprognostic (1.99e-1)" "potential prognostic unfavorable (3.95e-4)" "unprognostic (1.76e-1)" "unprognostic (1.77e-1)" "unprognostic (4.03e-3)" "unprognostic (7.55e-3)" "unprognostic (4.26e-1)" "unprognostic (7.81e-2)" "unprognostic (8.25e-2)" NOP2 "NOL1, NOP120, NSUN1, p120" ENSG00000111641 "NOP2 nucleolar protein" P46087 12 6556863-6568691 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 10.3;Bergmann glia: 8.7;Brain excitatory neurons: 10.0;Brain inhibitory neurons: 10.6;Choroid plexus epithelial cells: 7.9;Enteric stem cells: 7.0;Ependymal cells: 6.8;Epididymal basal cells: 7.1;Microglia: 13.0;Oligodendrocyte progenitor cells: 6.9;Oligodendrocytes: 7.6;Other brain neurons: 9.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040119 Supported Enhanced Nucleoli No No "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 48: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 98: Neurons - Neurotransmission & signaling" 78 Nucleoli "HPA040119: " "unprognostic (4.02e-2)" "unprognostic (1.57e-1)" "unprognostic (2.28e-1)" "unprognostic (8.53e-3)" "unprognostic (1.18e-1)" "unprognostic (9.89e-2)" "unprognostic (2.40e-1)" "potential prognostic favorable (5.16e-4)" "unprognostic (6.17e-2)" "unprognostic (1.83e-3)" "potential prognostic unfavorable (7.71e-4)" "unprognostic (2.02e-3)" "unprognostic (4.30e-3)" "potential prognostic unfavorable (1.62e-6)" "unprognostic (5.55e-3)" "potential prognostic unfavorable (2.30e-4)" "unprognostic (7.47e-3)" "unprognostic (6.23e-2)" "unprognostic (3.04e-1)" "unprognostic (2.47e-2)" "unprognostic (7.15e-3)" "unprognostic (4.20e-2)" "unprognostic (2.41e-2)" "unprognostic (1.03e-1)" "unprognostic (3.46e-3)" "unprognostic (7.41e-2)" "unprognostic (4.47e-2)" "unprognostic (8.79e-3)" "unprognostic (3.03e-1)" "unprognostic (1.28e-1)" "unprognostic (3.02e-1)" NOP53 "GLTSCR2, PICT-1, PICT1" ENSG00000105373 "NOP53 ribosome biogenesis factor" Q9NZM5 19 47745546-47757058 "Essential proteins, Predicted intracellular proteins" "Host-virus interaction, Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ovarian stromal cells: 962.8;Pancreatic acinar cells: 1100.5" "Cell type enhanced" "Detected in all" "leukocyte: 134.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "B-cells: 313.6;NK-cells: 97.4;T-cells: 245.6" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018999, HPA049600" Approved Supported Nucleoli NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 54: Non-specific - Ribosome" "Cluster 47: Endothelial cells - Vasculature" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 103 Nucleoli "HPA018999: , HPA049600: " "potential prognostic favorable (9.32e-4)" "unprognostic (1.27e-3)" "unprognostic (2.49e-1)" "unprognostic (2.60e-2)" "unprognostic (6.66e-2)" "unprognostic (4.89e-2)" "unprognostic (1.88e-1)" "unprognostic (2.13e-1)" "unprognostic (5.96e-2)" "unprognostic (2.42e-2)" "potential prognostic favorable (4.94e-5)" "unprognostic (2.37e-1)" "unprognostic (1.77e-1)" "unprognostic (2.11e-1)" "unprognostic (9.72e-2)" "unprognostic (4.08e-3)" "unprognostic (1.57e-1)" "unprognostic (5.71e-2)" "unprognostic (1.12e-1)" "unprognostic (3.30e-3)" "unprognostic (1.00e-2)" "unprognostic (1.33e-1)" "unprognostic (4.37e-1)" "unprognostic (2.58e-1)" "unprognostic (1.21e-2)" "unprognostic (6.32e-2)" "unprognostic (1.22e-1)" "unprognostic (1.82e-1)" "unprognostic (4.30e-2)" NOP56 "NOL5A, SCA36" ENSG00000101361 "NOP56 ribonucleoprotein" O00567 20 2652593-2658393 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Ribosome biogenesis" Ribonucleoprotein "Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 232.3;Oocytes: 303.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049918, CAB075757" Supported Enhanced "Nucleoli fibrillar center" NA NA 10000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 54: Non-specific - Ribosome" "Cluster 14: Neurons - Synaptic function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 17: Non-specific - RNA processing" 169 "Nucleoli fibrillar center" "CAB075757: , HPA049918: " "unprognostic (6.69e-3)" "unprognostic (1.66e-1)" "unprognostic (2.25e-2)" "unprognostic (6.58e-3)" "unprognostic (1.60e-1)" "unprognostic (7.83e-2)" "unprognostic (2.76e-1)" "unprognostic (4.29e-3)" "unprognostic (1.51e-1)" "unprognostic (7.75e-3)" "unprognostic (8.02e-2)" "unprognostic (6.23e-2)" "potential prognostic unfavorable (1.73e-4)" "validated prognostic unfavorable (4.94e-11)" "validated prognostic unfavorable (5.96e-6)" "unprognostic (3.95e-3)" "potential prognostic unfavorable (3.77e-4)" "unprognostic (1.67e-1)" "unprognostic (6.42e-2)" "unprognostic (7.68e-2)" "unprognostic (1.28e-3)" "unprognostic (4.66e-2)" "unprognostic (2.76e-2)" "unprognostic (9.32e-2)" "unprognostic (1.22e-2)" "unprognostic (2.06e-1)" "unprognostic (5.22e-1)" "unprognostic (6.94e-2)" "unprognostic (2.15e-1)" "unprognostic (9.11e-3)" "unprognostic (8.52e-2)" NOP58 "HSPC120, NOP5" ENSG00000055044 "NOP58 ribonucleoprotein" Q9Y2X3 2 202265736-202303661 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Ribosome biogenesis" Ribonucleoprotein "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018472, HPA021062" Supported Enhanced "Nucleoplasm,Nucleoli fibrillar center" NA Yes 37000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 9: T-cells - Adaptive immunity: Regulation" 80 "Nucleoli fibrillar center" Nucleoplasm "HPA018472: , HPA021062: " "unprognostic (3.21e-2)" "unprognostic (7.33e-3)" "unprognostic (5.00e-2)" "unprognostic (1.85e-1)" "unprognostic (1.23e-2)" "unprognostic (1.22e-1)" "unprognostic (2.89e-1)" "unprognostic (6.80e-2)" "unprognostic (4.48e-3)" "unprognostic (1.50e-1)" "unprognostic (7.98e-2)" "unprognostic (2.25e-1)" "potential prognostic unfavorable (5.18e-8)" "validated prognostic unfavorable (3.75e-7)" "validated prognostic unfavorable (2.23e-4)" "unprognostic (1.94e-3)" "unprognostic (1.91e-3)" "unprognostic (6.89e-2)" "unprognostic (2.94e-2)" "unprognostic (3.71e-2)" "unprognostic (1.01e-1)" "unprognostic (1.78e-2)" "unprognostic (2.20e-3)" "unprognostic (4.16e-3)" "unprognostic (1.80e-1)" "unprognostic (3.12e-1)" "unprognostic (4.11e-2)" "unprognostic (7.91e-2)" "unprognostic (2.32e-1)" "unprognostic (3.48e-1)" "unprognostic (5.40e-1)" NOP9 C14orf21 ENSG00000196943 "NOP9 nucleolar protein" Q86U38 14 24299850-24309124 "Essential proteins, Plasma proteins, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cholangiocytes: 3.9;Early spermatids: 2.7;Esophageal apical cells: 2.5;Retinal pigment epithelial cells: 4.3" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000850 Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 19: Astrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 13 Nucleoplasm "Nucleoli, Cytosol" "HPA000850: " "unprognostic (2.61e-1)" "unprognostic (9.19e-2)" "unprognostic (4.15e-3)" "unprognostic (2.39e-2)" "unprognostic (3.75e-2)" "unprognostic (1.18e-1)" "unprognostic (2.64e-3)" "unprognostic (1.82e-1)" "unprognostic (1.86e-3)" "validated prognostic favorable (2.99e-6)" "validated prognostic favorable (2.12e-4)" "unprognostic (7.95e-3)" "unprognostic (2.46e-2)" "unprognostic (3.20e-1)" "unprognostic (8.32e-3)" "unprognostic (9.66e-2)" "unprognostic (6.66e-2)" "unprognostic (7.62e-3)" "unprognostic (4.72e-1)" "unprognostic (2.00e-1)" "unprognostic (5.17e-2)" "unprognostic (1.23e-2)" "unprognostic (4.69e-2)" "unprognostic (9.63e-2)" "unprognostic (2.83e-1)" "unprognostic (2.04e-2)" "unprognostic (2.11e-1)" "unprognostic (1.15e-1)" "unprognostic (1.35e-1)" NOPCHAP1 "C12orf45, DDSR1, MGC40397" ENSG00000151131 "NOP protein chaperone 1" Q8N5I9 12 104986316-105074197 "Essential proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 225.6;pDCs: 237.5;Plasma cells: 126.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "plasmacytoid DC: 463.3" "Lineage enriched" "Detected in all" 13 "dendritic cells: 463.3" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA038722 Uncertain Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 9: Non-specific - Receptor signaling" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 13 Nucleoplasm "Nuclear membrane" "HPA038722: " "unprognostic (5.11e-2)" "unprognostic (4.80e-2)" "unprognostic (4.56e-2)" "unprognostic (9.28e-2)" "unprognostic (2.34e-1)" "unprognostic (1.10e-1)" "unprognostic (3.00e-3)" "unprognostic (1.93e-2)" "unprognostic (6.14e-3)" "unprognostic (8.74e-2)" "validated prognostic unfavorable (2.67e-7)" "validated prognostic unfavorable (1.08e-4)" "unprognostic (1.79e-1)" "unprognostic (7.07e-3)" "unprognostic (2.19e-2)" "unprognostic (4.17e-3)" "potential prognostic unfavorable (5.07e-4)" "unprognostic (1.33e-2)" "unprognostic (1.04e-1)" "unprognostic (1.90e-1)" "unprognostic (1.51e-2)" "unprognostic (7.03e-3)" "unprognostic (6.41e-2)" "unprognostic (1.42e-1)" "unprognostic (1.23e-1)" "unprognostic (2.71e-1)" "potential prognostic unfavorable (8.20e-4)" "unprognostic (2.24e-1)" "unprognostic (1.52e-1)" "unprognostic (5.81e-2)" "potential prognostic favorable (9.80e-4)" NOS1 "nNOS, NOS" ENSG00000089250 "Nitric oxide synthase 1" P29475 12 117208142-117452170 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Calmodulin-binding, Oxidoreductase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "skeletal muscle: 34.5;tongue: 53.5" "Cell type enriched" "Detected in many" 4 "Myonuclei: 889.9" "Cell type enhanced" "Detected in all" "cerebellar inhibitory: 194.9;LAMP5-LHX6 and Chandelier: 205.1;splatter: 285.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Esophageal cancer: 4.5;Sarcoma: 4.2" "Adipose visceral - Smooth muscle cells, Colon - Colon enteroendocrine cells, Pituitary gland - Corticotropes, Prostate - Prostate basal glandular cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002167, HPA058312, HPA069509" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 24: Neurons - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 8 "Plasma membrane" Nucleoplasm "CAB002167: , HPA058312: , HPA069509: " "unprognostic (8.60e-2)" "unprognostic (2.45e-1)" "unprognostic (2.71e-1)" "unprognostic (6.84e-3)" "unprognostic (5.58e-2)" NOS1AP "CAPON, KIAA0464" ENSG00000198929 "Nitric oxide synthase 1 adaptor protein" O75052 1 162069691-162370475 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 16.3" "Cell type enhanced" "Detected in many" "Bergmann glia: 778.7;Choroid plexus epithelial cells: 299.7;Distal convoluted tubule cells: 749.4;Podocytes: 515.7;Renal collecting duct principal cells: 339.9;Renal connecting tubule cells: 293.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "CAB018582, HPA030066, HPA055561" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 51: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 24 "Nucleoplasm, Vesicles" "CAB018582: , HPA030066: , HPA055561: " "unprognostic (9.36e-3)" "unprognostic (1.92e-1)" "unprognostic (9.80e-2)" "unprognostic (1.04e-1)" "unprognostic (2.45e-2)" "unprognostic (7.51e-2)" "unprognostic (1.71e-1)" "unprognostic (7.93e-3)" "unprognostic (1.85e-1)" "unprognostic (5.58e-3)" "unprognostic (1.88e-1)" "unprognostic (1.90e-1)" "unprognostic (2.28e-2)" NOS2 "HEP-NOS, iNOS, NOS, NOS2A" ENSG00000007171 "Nitric oxide synthase 2" P35228 17 27756766-27800529 "Cancer-related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Calmodulin-binding, Oxidoreductase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 19.6;lymphoid tissue: 13.8" "Cell type enhanced" "Detected in some" "Enteric stem cells: 26.2;Enteric transient amplifying cells: 11.6;Enterocytes: 15.6;Extravillous trophoblasts: 47.6;Granulosa cells: 8.1;Ocular epithelial cells: 17.9;Paneth cells: 15.5;Respiratory basal cells: 27.8;Respiratory deuterosomal cells: 11.4;Respiratory secretory cells: 52.8" "Cell type enhanced" "Detected in many" "upper-layer intratelencephalic: 4.5" "Group enriched" "Detected in many" 4 "Colon Adenocarcinoma (TCGA): 21.5;Glioblastoma Multiforme (TCGA): 13.7;Lung Squamous Cell Carcinoma (TCGA): 15.9;Rectum Adenocarcinoma (TCGA): 15.6;Stomach Adenocarcinoma (TCGA): 10.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 2.7;Uterine cancer: 2.6" "Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB002014 Enhanced NA NA "Cluster 77: Intestine - Digestion" "Cluster 53: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 100: Stratified epithelial cells - Barrier functions" 11 "CAB002014: " "unprognostic (1.28e-2)" "unprognostic (2.79e-1)" "unprognostic (4.81e-2)" "unprognostic (1.88e-2)" "unprognostic (1.07e-3)" "unprognostic (1.50e-1)" "unprognostic (1.06e-1)" "unprognostic (9.89e-3)" "validated prognostic favorable (2.97e-6)" "validated prognostic favorable (3.38e-4)" "unprognostic (8.32e-3)" "unprognostic (2.39e-3)" "unprognostic (8.46e-2)" "unprognostic (1.37e-2)" "unprognostic (9.59e-2)" NOS3 "ECNOS, eNOS" ENSG00000164867 "Nitric oxide synthase 3" P29474 7 150991017-151014588 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Calmodulin-binding, Oxidoreductase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 59.4" "Group enriched" "Detected in some" 4 "Early spermatids: 95.6;Late primary spermatocytes: 60.9;Late spermatids: 47.7;Lymphatic endothelial cells: 27.7;Syncytiotrophoblasts: 28.5;Vascular endothelial cells: 56.4" "Cell type enriched" "Detected in some" 8 "endothelial cell: 82.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Lineage enriched" "Detected in single" 4 "T-cells: 2.3" "Low cancer specificity" "Detected in many" "Adrenal gland - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Pancreas - Endothelial cells, Pituitary gland - Endothelial cells, Prostate - Endothelial cells, Stomach - Endothelial cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB002168 Enhanced NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 5: Spleen - Immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 59 "CAB002168: " "unprognostic (2.72e-1)" "unprognostic (7.54e-2)" "unprognostic (3.21e-3)" "unprognostic (4.80e-2)" "unprognostic (3.78e-2)" "unprognostic (8.85e-2)" "unprognostic (2.07e-1)" "unprognostic (7.01e-2)" "unprognostic (6.27e-2)" "unprognostic (2.01e-2)" "potential prognostic favorable (3.84e-6)" "unprognostic (1.29e-3)" "potential prognostic unfavorable (2.68e-5)" "unprognostic (9.37e-2)" "potential prognostic favorable (3.24e-4)" "unprognostic (3.48e-2)" "unprognostic (3.66e-1)" "unprognostic (3.60e-2)" "unprognostic (1.37e-1)" "unprognostic (1.03e-1)" "unprognostic (1.62e-1)" "unprognostic (5.40e-2)" "unprognostic (1.84e-1)" "unprognostic (2.17e-1)" "unprognostic (2.18e-1)" "unprognostic (1.50e-1)" "unprognostic (8.03e-3)" "unprognostic (7.31e-3)" "unprognostic (8.63e-2)" "unprognostic (2.28e-2)" "unprognostic (4.11e-1)" NOSIP CGI-25 ENSG00000142546 "Nitric oxide synthase interacting protein" Q9Y314 19 49555468-49590262 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Developmental protein, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 345.5;Esophageal apical cells: 288.6;Late primary spermatocytes: 604.9;Late spermatids: 1225.5;Pancreatic acinar cells: 295.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043464, HPA062132" Approved Enhanced Nucleoplasm NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 24: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 14 Nucleoplasm "HPA043464: , HPA062132: " "unprognostic (2.74e-1)" "unprognostic (6.43e-2)" "unprognostic (1.23e-2)" "unprognostic (9.44e-2)" "unprognostic (2.61e-1)" "unprognostic (2.53e-1)" "unprognostic (1.29e-2)" "unprognostic (5.10e-2)" "unprognostic (3.52e-1)" "unprognostic (1.41e-1)" "potential prognostic favorable (5.28e-4)" "unprognostic (2.35e-2)" "unprognostic (4.40e-2)" "potential prognostic unfavorable (8.35e-4)" "unprognostic (5.23e-3)" "unprognostic (3.41e-2)" "unprognostic (2.60e-1)" "unprognostic (3.98e-2)" "unprognostic (4.36e-1)" "unprognostic (1.01e-1)" "unprognostic (1.74e-1)" "unprognostic (1.02e-2)" "unprognostic (1.63e-1)" "unprognostic (9.24e-2)" "unprognostic (4.47e-1)" "unprognostic (2.54e-2)" "unprognostic (2.58e-1)" "unprognostic (4.52e-2)" "unprognostic (2.76e-1)" "unprognostic (1.19e-1)" "unprognostic (2.94e-1)" NOSTRIN MGC20702 ENSG00000163072 "Nitric oxide synthase trafficking" Q8IVI9 2 168786539-168865514 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast lactating cells: 129.6;Enterocytes: 105.9;Epididymal efferent duct absorptive cells: 58.6;Late spermatids: 77.8;Pancreatic acinar cells: 65.7;Proximal tubule cells: 67.1;Salivary acinar cells: 137.2;Sertoli cells: 144.4;Vascular endothelial cells: 241.7" "Group enriched" "Detected in many" 5 "endothelial cell: 577.6;pericyte: 148.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 8.4;Gastric cancer: 9.9" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Pituitary gland - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044384, HPA076885" Approved Approved Vesicles,Cytosol NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 5 Cytosol Vesicles "HPA044384: , HPA076885: " "unprognostic (9.08e-3)" "unprognostic (3.98e-1)" "unprognostic (1.01e-1)" "unprognostic (1.83e-1)" "unprognostic (1.88e-2)" "unprognostic (1.19e-2)" "unprognostic (2.68e-1)" "unprognostic (4.86e-2)" "validated prognostic favorable (9.20e-12)" "validated prognostic favorable (6.42e-5)" "unprognostic (4.21e-3)" "unprognostic (1.03e-2)" "unprognostic (8.78e-2)" "unprognostic (2.49e-1)" "unprognostic (6.81e-3)" "unprognostic (4.19e-3)" "unprognostic (1.06e-1)" "unprognostic (2.27e-2)" "unprognostic (3.44e-2)" "unprognostic (2.42e-1)" "unprognostic (3.53e-1)" "unprognostic (2.25e-1)" "unprognostic (9.75e-3)" "unprognostic (1.64e-2)" "unprognostic (2.05e-1)" "unprognostic (1.41e-1)" "unprognostic (1.61e-1)" "unprognostic (9.08e-2)" NOTCH1 TAN1 ENSG00000148400 "Notch receptor 1" P46531 9 136494433-136546048 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Angiogenesis, Differentiation, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, Receptor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 77.3;Lymphatic endothelial cells: 92.8;Müller glia: 83.5;Neutrophils: 213.5;Vascular endothelial cells: 83.3" "Cell type enhanced" "Detected in many" "astrocyte: 88.9;endothelial cell: 116.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 2.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adrenal gland - Endothelial cells, Heart muscle - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008112, CAB022466, HPA067168" Supported Approved Nucleoplasm NA NA 9900000 "Cluster 21: Neutrophils - Unknown function" "Cluster 2: Non-specific - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 24: Neutrophils - Innate immunity signal integration" 107 Nucleoplasm "CAB008112: , CAB022466: , HPA067168: " "unprognostic (7.30e-2)" "unprognostic (1.75e-1)" "unprognostic (2.05e-1)" "unprognostic (2.39e-2)" "unprognostic (2.70e-1)" "unprognostic (1.46e-1)" "unprognostic (1.50e-1)" "unprognostic (2.24e-3)" "unprognostic (1.00e-1)" "unprognostic (1.44e-1)" "validated prognostic favorable (9.19e-6)" "validated prognostic favorable (4.90e-4)" "potential prognostic unfavorable (2.84e-4)" "unprognostic (1.74e-1)" "unprognostic (1.24e-3)" "unprognostic (1.48e-1)" "unprognostic (7.15e-3)" "unprognostic (1.83e-2)" "unprognostic (4.29e-2)" "unprognostic (1.90e-1)" "unprognostic (2.34e-2)" "unprognostic (2.91e-1)" "unprognostic (3.86e-2)" "unprognostic (2.76e-2)" "unprognostic (7.28e-2)" "unprognostic (1.32e-1)" "unprognostic (5.40e-2)" "unprognostic (9.44e-2)" "unprognostic (4.00e-3)" "unprognostic (1.58e-1)" NOTCH2 ENSG00000134250 "Notch receptor 2" Q04721 1 119911553-120100779 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, Receptor" "Cancer-related genes, Disease variant, Osteoporosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 320.6;Neutrophils: 726.4" "Cell type enhanced" "Detected in all" "Bergmann glia: 211.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048743 Approved Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA 26000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 24: Neutrophils - Innate immunity signal integration" 49 "Nucleoplasm, Plasma membrane" "Golgi apparatus" "HPA048743: " "unprognostic (4.09e-2)" "unprognostic (2.32e-1)" "unprognostic (2.27e-1)" "unprognostic (2.00e-2)" "unprognostic (1.24e-1)" "unprognostic (4.68e-2)" "unprognostic (7.39e-2)" "unprognostic (2.84e-1)" "unprognostic (5.64e-2)" "unprognostic (4.21e-2)" "potential prognostic favorable (7.88e-4)" "unprognostic (6.60e-2)" "unprognostic (1.11e-1)" "unprognostic (1.26e-1)" "unprognostic (4.48e-1)" "unprognostic (1.08e-1)" "unprognostic (1.69e-3)" "unprognostic (4.58e-1)" "unprognostic (1.45e-1)" "unprognostic (6.54e-3)" "unprognostic (1.35e-2)" "unprognostic (1.01e-3)" "unprognostic (1.01e-1)" "unprognostic (1.15e-1)" "unprognostic (1.74e-1)" "unprognostic (1.19e-1)" "unprognostic (9.53e-3)" "unprognostic (5.59e-2)" "unprognostic (3.60e-2)" "unprognostic (3.95e-2)" "unprognostic (1.22e-2)" NOTCH2NLA "N2N, NOTCH2NL" ENSG00000264343 "Notch 2 N-terminal like A" Q7Z3S9 1 146146203-146229041 "Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Notch signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in some" 9 "Tuft cells: 23.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 40.4;classical monocyte: 46.9;eosinophil: 90.4;intermediate monocyte: 40.9;memory B-cell: 76.3;myeloid DC: 61.1;naive B-cell: 44.2;neutrophil: 42.9;non-classical monocyte: 42.1;plasmacytoid DC: 49.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" CAB004669 Uncertain "Secreted to blood" "Developmental protein" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 12: Non-specific - Vasculature" "Cluster 45: Non-specific - Nuclear processes" "Cluster 95: Tuft cells - Chemosensory signaling" 203 "CAB004669: " "unprognostic (9.89e-3)" "unprognostic (2.16e-1)" "unprognostic (1.12e-2)" "unprognostic (3.75e-1)" "unprognostic (1.06e-2)" "unprognostic (2.43e-1)" "unprognostic (2.62e-1)" "unprognostic (3.25e-2)" "unprognostic (6.27e-3)" "unprognostic (1.65e-1)" "unprognostic (2.52e-1)" "unprognostic (6.93e-2)" "unprognostic (1.33e-1)" "unprognostic (2.14e-2)" "unprognostic (1.98e-1)" "unprognostic (2.82e-1)" "unprognostic (2.19e-3)" "unprognostic (7.16e-3)" "unprognostic (7.29e-2)" "unprognostic (5.80e-1)" "unprognostic (1.08e-1)" "unprognostic (1.42e-1)" "unprognostic (5.14e-2)" "unprognostic (2.58e-1)" "unprognostic (1.21e-1)" "unprognostic (9.91e-2)" NOTCH2NLB ENSG00000286019 "Notch 2 N-terminal like B" P0DPK3 1 148600285-148679746 "Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Notch signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Secreted to blood" Other NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 74: Non-specific - Signal transduction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 45: Non-specific - Nuclear processes" "Cluster 100: Stratified epithelial cells - Barrier functions" "potential prognostic unfavorable (6.94e-5)" "unprognostic (6.42e-2)" "unprognostic (3.13e-2)" "unprognostic (9.18e-2)" "unprognostic (3.72e-1)" "unprognostic (1.17e-1)" "unprognostic (9.33e-2)" "unprognostic (9.78e-3)" "unprognostic (2.21e-1)" "unprognostic (1.43e-1)" "unprognostic (1.57e-1)" "unprognostic (3.04e-1)" "unprognostic (1.97e-1)" "unprognostic (8.30e-2)" "unprognostic (1.81e-1)" "unprognostic (2.69e-1)" "unprognostic (1.54e-2)" "unprognostic (2.21e-2)" "unprognostic (1.90e-1)" "unprognostic (2.72e-2)" "unprognostic (4.00e-2)" "unprognostic (9.64e-2)" "unprognostic (7.77e-3)" "unprognostic (1.63e-1)" "unprognostic (3.78e-1)" "unprognostic (1.85e-1)" NOTCH2NLC ENSG00000286219 "Notch 2 N-terminal like C" P0DPK4 1 149390621-149471833 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Notch signaling pathway" Neurodegeneration "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Secreted to blood" Other NA NA "Cluster 41: Basophils - Unknown function" "Cluster 40: Non-specific - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 45: Non-specific - Nuclear processes" "Cluster 67: Plasma cells - Plasma cell differentiation" 178 "unprognostic (1.51e-3)" "unprognostic (5.67e-2)" "unprognostic (6.16e-3)" "unprognostic (1.26e-1)" "unprognostic (1.75e-1)" "unprognostic (9.43e-2)" "unprognostic (1.73e-1)" "unprognostic (1.77e-1)" "unprognostic (6.24e-3)" "unprognostic (1.15e-1)" "unprognostic (1.52e-1)" "unprognostic (1.19e-1)" "unprognostic (2.53e-1)" "unprognostic (1.60e-3)" "unprognostic (1.97e-1)" "unprognostic (9.31e-2)" "unprognostic (2.23e-1)" "unprognostic (1.56e-2)" "unprognostic (1.10e-1)" "unprognostic (6.56e-2)" "unprognostic (1.07e-1)" "unprognostic (1.26e-1)" "unprognostic (1.53e-2)" "unprognostic (3.85e-1)" "unprognostic (1.91e-1)" "unprognostic (5.45e-2)" NOTCH2NLR ENSG00000286106 "Notch 2 N-terminal like R (pseudogene)" 1 120723912-120794851 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cholangiocytes: 2.0;Decidual stromal cells: 2.6;Early spermatids: 1.8;Epididymal principal cells: 1.9;Esophageal apical cells: 4.5;Esophageal suprabasal cells: 2.0;Extravillous trophoblasts: 2.5;Gastric progenitor cells: 2.6;Late primary spermatocytes: 4.1;Late spermatids: 2.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 5 "granulocytes: 8.0;monocytes: 5.2" "Low cancer specificity" "Detected in many" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 47: Testis - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 45: Non-specific - Nuclear processes" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" "unprognostic (2.57e-2)" "unprognostic (5.17e-2)" "unprognostic (6.09e-3)" "unprognostic (1.10e-1)" "unprognostic (2.51e-1)" "unprognostic (3.46e-2)" "unprognostic (4.36e-1)" "unprognostic (2.63e-1)" "unprognostic (2.14e-1)" "unprognostic (3.31e-1)" "unprognostic (1.48e-2)" "potential prognostic favorable (7.98e-4)" "unprognostic (8.76e-2)" "unprognostic (1.30e-1)" "unprognostic (1.51e-2)" "unprognostic (4.13e-1)" "unprognostic (7.23e-2)" "unprognostic (1.50e-2)" "unprognostic (3.51e-2)" "unprognostic (1.38e-1)" "unprognostic (5.06e-2)" "unprognostic (1.77e-2)" NOTCH3 "CADASIL, CASIL" ENSG00000074181 "Notch receptor 3" Q9UM47 19 15159038-15200995 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, Receptor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 200.8" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 126.7;Esophageal basal cells: 100.5;Esophageal suprabasal cells: 164.7;Hepatic stellate cells: 96.8;Myosatellite cells: 145.8;Pericytes: 497.7;Suprabasal keratinocytes: 127.3;Vascular smooth muscle cells: 532.4" "Group enriched" "Detected in many" 95 "pericyte: 876.5;vascular associated smooth muscle cell: 608.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 85.0" "Breast - Endothelial cells, Prostate - Endothelial cells, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005393, HPA044392, HPA067424" Approved Supported "Nucleoplasm,Plasma membrane" NA NA 15000000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 110: Mural cells - ECM organization" 12 "Nucleoplasm, Plasma membrane" "CAB005393: , HPA044392: , HPA067424: " "unprognostic (1.01e-1)" "unprognostic (5.13e-2)" "unprognostic (1.90e-1)" "unprognostic (4.22e-2)" "unprognostic (1.58e-3)" "unprognostic (8.11e-2)" "unprognostic (1.38e-1)" "unprognostic (6.16e-3)" "unprognostic (4.17e-3)" "unprognostic (1.10e-2)" "unprognostic (3.65e-3)" "unprognostic (5.08e-3)" "potential prognostic unfavorable (9.86e-7)" "unprognostic (2.63e-1)" "unprognostic (2.34e-1)" "unprognostic (3.57e-2)" "potential prognostic unfavorable (1.06e-4)" "unprognostic (2.28e-1)" "unprognostic (6.40e-2)" "unprognostic (3.03e-1)" "unprognostic (3.36e-1)" "unprognostic (1.94e-1)" "unprognostic (1.78e-1)" "unprognostic (3.73e-1)" "unprognostic (1.23e-1)" "unprognostic (1.11e-2)" "unprognostic (3.57e-2)" "unprognostic (3.81e-2)" "unprognostic (1.17e-2)" "unprognostic (5.59e-2)" "unprognostic (8.07e-2)" NOTCH4 INT3 ENSG00000204301 "Notch receptor 4" Q99466 6 32194843-32224067 "Human disease related genes, Predicted membrane proteins" "Differentiation, Host-virus interaction, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 22.4" "Group enriched" "Detected in some" 5 "Papillary tip epithelial cells: 5.1;Vascular endothelial cells: 17.9" "Cell type enriched" "Detected in some" 14 "endothelial cell: 141.3" "Cancer enriched" "Detected in single" 4 "Kidney Renal Clear Cell Carcinoma (TCGA): 2.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Pancreas - Endothelial cells, Pituitary gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" NA NA 30000000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 2 "unprognostic (1.17e-1)" "unprognostic (6.63e-2)" "unprognostic (3.39e-2)" "potential prognostic favorable (8.91e-4)" "unprognostic (1.15e-2)" "unprognostic (3.19e-2)" NOTO ENSG00000214513 "Notochord homeobox" A8MTQ0 2 73202574-73212513 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Epididymal basal cells: 1.4;Gastric chief cells: 1.1;Syncytiotrophoblasts: 1.2;Undifferentiated spermatogonia: 1.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "thyroid cancer: 2.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA034660, HPA063906" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 25: Non-specific - Transcription" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 25 Nucleoplasm Cytosol "HPA034660: , HPA063906: " "potential prognostic unfavorable (1.79e-4)" NOTUM ENSG00000185269 "Notum, palmitoleoyl-protein carboxylesterase" Q6P988 17 81952507-81961840 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "placenta: 127.5" "Cell type enriched" "Detected in some" 44 "Extravillous trophoblasts: 1955.2" "Cell type enhanced" "Detected in many" "astrocyte: 8.1;endothelial cell: 13.1" "Cancer enhanced" "Detected in many" "Stomach Adenocarcinoma (TCGA): 113.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 49.8" "Breast - Breast glandular cells (progenitors), Heart muscle - Cardiomyocytes, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA022851 Approved "Endoplasmic reticulum" "Secreted in female reproductive system" Enzyme NA NA 2000000 "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 1 "Endoplasmic reticulum" "HPA022851: " "unprognostic (3.31e-2)" "unprognostic (9.11e-2)" "unprognostic (1.67e-1)" "unprognostic (4.21e-3)" "unprognostic (1.60e-1)" "unprognostic (6.02e-3)" "unprognostic (2.48e-2)" "unprognostic (1.10e-2)" "unprognostic (5.02e-3)" "unprognostic (3.47e-2)" "unprognostic (3.70e-1)" "unprognostic (7.54e-2)" "unprognostic (1.22e-1)" "unprognostic (4.94e-2)" "unprognostic (2.19e-1)" "unprognostic (1.60e-1)" "unprognostic (9.88e-2)" "unprognostic (7.82e-2)" "unprognostic (5.56e-3)" "unprognostic (9.15e-2)" "unprognostic (1.82e-1)" "unprognostic (1.44e-1)" "potential prognostic favorable (4.45e-4)" NOVA1 NOVA-1 ENSG00000139910 "NOVA alternative splicing regulator 1" P51513 14 26443090-26598033 "Predicted intracellular proteins" "mRNA processing, mRNA splicing, Neurogenesis" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 64.0" "Cell type enhanced" "Detected in many" "Bergmann glia: 684.6;Brain excitatory neurons: 778.2;Brain inhibitory neurons: 483.4;Corticotrophs: 708.7;Fibro-adipogenic progenitors: 2156.7;Leydig cells: 449.1;Oligodendrocyte progenitor cells: 2589.9;Oligodendrocytes: 566.3;Other brain neurons: 685.8;Thyrotrophs: 521.1" "Cell type enhanced" "Detected in all" "oligodendrocyte precursor cell: 3101.9" "Cancer enriched" "Detected in many" 5 "Glioblastoma Multiforme (TCGA): 95.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Liver - Vascular endothelial cells, Lung - Fibroblasts_2, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004155 Uncertain Supported Nucleoplasm,Nucleoli NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 27: Breast cancer - Unknown function" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 4 Nucleoli Nucleoplasm "HPA004155: " "unprognostic (4.13e-2)" "unprognostic (2.36e-1)" "unprognostic (6.52e-2)" "unprognostic (6.70e-2)" "unprognostic (5.97e-3)" "unprognostic (6.08e-3)" "unprognostic (1.12e-1)" "unprognostic (5.62e-3)" "unprognostic (3.52e-2)" "unprognostic (2.69e-1)" "unprognostic (5.17e-3)" "unprognostic (7.41e-3)" "unprognostic (3.73e-2)" "unprognostic (2.23e-1)" "unprognostic (2.70e-2)" "unprognostic (1.65e-1)" "unprognostic (8.40e-2)" "unprognostic (6.98e-2)" "potential prognostic favorable (5.77e-4)" "unprognostic (7.07e-2)" "unprognostic (9.76e-2)" "unprognostic (1.52e-1)" "unprognostic (1.36e-3)" "unprognostic (8.31e-2)" "unprognostic (2.75e-2)" "unprognostic (7.12e-2)" NOVA2 "ANOVA, NOVA-2, NOVA3" ENSG00000104967 "NOVA alternative splicing regulator 2" Q9UNW9 19 45933734-45974044 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing, Neurogenesis" RNA-binding "Autism spectrum disorder, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.3" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 39.1;Brain inhibitory neurons: 47.6;Corticotrophs: 29.1;Lactotrophs: 23.8;Lymphatic endothelial cells: 54.0;Oligodendrocyte progenitor cells: 29.2;Oligodendrocytes: 20.0;Other brain neurons: 38.3;Retinal amacrine cells: 46.1;Retinal bipolar cells: 80.4;Vascular endothelial cells: 68.9" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 12.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Neuroblastoma: 11.5" "Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Lung - Endothelial cells, Minor Salivary Gland - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells, Thyroid gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045607 Enhanced Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus" No No "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" "Golgi apparatus" "Nucleoplasm, Nuclear bodies" "HPA045607: " "unprognostic (1.33e-1)" "unprognostic (2.57e-2)" "unprognostic (1.20e-1)" "unprognostic (2.23e-2)" "unprognostic (3.15e-1)" "unprognostic (2.13e-1)" "unprognostic (2.27e-3)" "validated prognostic favorable (1.18e-5)" "validated prognostic favorable (5.48e-5)" "unprognostic (2.48e-3)" "unprognostic (1.18e-1)" "unprognostic (8.36e-2)" "unprognostic (1.84e-2)" "unprognostic (1.46e-3)" "unprognostic (8.26e-3)" "unprognostic (1.55e-2)" "unprognostic (3.84e-2)" "unprognostic (2.41e-1)" "unprognostic (3.14e-1)" "unprognostic (1.47e-1)" "unprognostic (7.05e-3)" NOX1 "GP91-2, MOX1, NOH-1, NOH-1L, NOH1" ENSG00000007952 "NADPH oxidase 1" Q9Y5S8 X 100843324-100874359 "Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Electron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 24 "intestine: 67.4" "Group enriched" "Detected in some" 4 "Colonocytes: 76.6;Enteric stem cells: 107.3;Enteric transient amplifying cells: 97.0" "Low cell type specificity" "Detected in some" "Group enriched" "Detected in many" 19 "Colon Adenocarcinoma (TCGA): 106.6;Rectum Adenocarcinoma (TCGA): 138.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "colorectal cancer: 16.4" "Colon - Colon enterocytes, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 17: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 2 "unprognostic (1.53e-1)" "unprognostic (1.80e-2)" "unprognostic (8.51e-2)" "unprognostic (1.53e-2)" "unprognostic (2.78e-3)" "unprognostic (1.12e-1)" "unprognostic (2.38e-2)" "unprognostic (1.78e-3)" "unprognostic (1.62e-2)" "unprognostic (2.61e-2)" "unprognostic (1.96e-2)" "unprognostic (5.21e-3)" "unprognostic (1.09e-1)" "unprognostic (2.44e-1)" "unprognostic (2.80e-1)" "unprognostic (3.18e-1)" NOX3 GP91-3 ENSG00000074771 "NADPH oxidase 3" Q9HBY0 6 155395368-155455839 "Predicted membrane proteins, Transporters" Oxidoreductase "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 10.6;Cholangiocytes: 2.0;Macrophages: 2.2;Mast cells: 4.8;Müller glia: 2.1;Plasma cells: 4.5;Retinal horizontal cells: 2.0;Sertoli cells: 2.2" "Cell type enhanced" "Detected in some" "hippocampal dentate gyrus: 9.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 8 "Rhabdoid: 9.4" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA073837 Uncertain Vesicles NA NA "Cluster 5: Rhabdoid - Unknown function" "Cluster 58: Mast cells - Allergic inflammatory responses" 1 Vesicles "HPA073837: " NOX4 "KOX, KOX-1" ENSG00000086991 "NADPH oxidase 4" Q9NPH5 11 89324353-89498187 "Predicted membrane proteins, Transporters" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "blood vessel: 35.3;kidney: 128.9" "Cell type enhanced" "Detected in many" "Fibro-adipogenic progenitors: 459.5;Fibroblasts: 146.3;Podocytes: 301.2;Proximal tubule cells: 978.1" "Cell type enhanced" "Detected in many" "fibroblast: 36.1;hippocampal CA1-3: 42.1;oligodendrocyte: 64.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "testis cancer: 6.5" "Breast - Endothelial cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 30: White matter - Myelination" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 88: Proximal tubular cells - Transmembrane transport" 2 "unprognostic (3.83e-1)" "unprognostic (6.44e-2)" "unprognostic (8.47e-2)" "unprognostic (5.32e-2)" "unprognostic (2.01e-2)" "unprognostic (7.00e-2)" "unprognostic (1.64e-1)" "unprognostic (1.61e-1)" "unprognostic (1.47e-1)" "unprognostic (2.86e-1)" "potential prognostic favorable (1.02e-5)" "unprognostic (1.93e-1)" "unprognostic (2.24e-3)" "unprognostic (1.03e-2)" "unprognostic (5.13e-2)" "unprognostic (5.99e-2)" "unprognostic (1.29e-1)" "unprognostic (2.03e-2)" "unprognostic (1.93e-3)" "unprognostic (3.91e-2)" "unprognostic (3.43e-2)" "unprognostic (2.02e-1)" "unprognostic (3.73e-2)" "unprognostic (2.25e-3)" "unprognostic (3.19e-2)" "unprognostic (1.72e-3)" "unprognostic (9.69e-3)" "unprognostic (1.08e-1)" "unprognostic (2.35e-1)" NOX5 "NOX5A, NOX5B" ENSG00000255346 "NADPH oxidase 5" Q96PH1 15 69014695-69062762 "Predicted membrane proteins, Transporters" "Angiogenesis, Electron transport, Ion transport, Transport" "Ion channel, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "lymphoid tissue: 8.1" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 1.8;Brain inhibitory neurons: 2.9;Choroid plexus epithelial cells: 1.7;Distal convoluted tubule cells: 2.8;Ependymal cells: 2.5;Loop of henle epithelial cells: 4.0;Other brain neurons: 1.7;Papillary tip epithelial cells: 2.9;Podocytes: 4.4;Proximal tubule cells: 4.3;Renal collecting duct intercalated cells: 7.7;Renal collecting duct principal cells: 5.6;Renal connecting tubule cells: 3.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "pancreatic cancer: 1.0;skin cancer: 1.0" "Skin - Outer root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" NA NA "Cluster 66: Lymphoid tissue - Immune response" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 102: Non-specific - Mixed function" "unprognostic (5.30e-3)" "unprognostic (1.77e-2)" "unprognostic (1.42e-2)" "unprognostic (5.96e-2)" "unprognostic (1.79e-1)" "unprognostic (2.96e-2)" NOX5 "NOX5A, NOX5B" ENSG00000290203 "NADPH oxidase 5" Q96PH1 15 68930504-69062743 "Predicted membrane proteins, Transporters" "Angiogenesis, Electron transport, Ion transport, Transport" "Ion channel, Oxidoreductase" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 7.3;Early primary spermatocytes: 16.9;Late primary spermatocytes: 5.2;Pituicytes/FSCs: 4.9;Retinal amacrine cells: 10.1;Sertoli cells: 9.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 15: Kidney cancer - Membrane components" "Cluster 3: Early primary spermatocytes - Early meiosis" NOXA1 "FLJ25475, NY-CO-31, SDCCAG31" ENSG00000188747 "NADPH oxidase activator 1" Q86UR1 9 137423350-137434406 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Colonocytes: 61.7;Foveolar cells: 69.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 2.6" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 44.1" "Skeletal muscle - Fibroblasts, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA044781 Uncertain Approved Vesicles NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 60: Stomach - Digestion" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 68: Foveolar cells - Mucosal defense" 3 Vesicles "HPA044781: " "unprognostic (6.72e-2)" "unprognostic (5.73e-2)" "unprognostic (3.26e-2)" "unprognostic (9.20e-2)" "unprognostic (6.02e-3)" "unprognostic (4.20e-2)" "unprognostic (4.18e-2)" "unprognostic (2.81e-1)" "unprognostic (9.05e-2)" "unprognostic (2.85e-2)" "unprognostic (3.52e-3)" "unprognostic (2.75e-2)" "potential prognostic favorable (2.96e-5)" "unprognostic (2.15e-1)" "unprognostic (1.87e-1)" "unprognostic (9.11e-3)" "unprognostic (1.39e-1)" "unprognostic (2.56e-1)" "unprognostic (1.81e-1)" "unprognostic (2.22e-1)" "unprognostic (8.64e-2)" "potential prognostic favorable (7.91e-4)" "unprognostic (8.64e-2)" "unprognostic (5.41e-3)" "unprognostic (2.63e-1)" "unprognostic (1.36e-1)" "unprognostic (1.20e-1)" "unprognostic (3.73e-2)" "unprognostic (1.86e-1)" "unprognostic (1.96e-1)" "unprognostic (1.25e-1)" NOXO1 "P41NOXA, P41NOXB, P41NOXC, SH3PXD5, SNX28" ENSG00000196408 "NADPH oxidase organizer 1" Q8NFA2 16 1978917-1984192 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.4;intestine: 8.1;lymphoid tissue: 4.4;testis: 4.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 17.3;Breast lactating cells: 53.6;Colonocytes: 52.1;Enteric stem cells: 29.5;Enteric transient amplifying cells: 26.8;Esophageal apical cells: 93.1;Goblet cells: 26.1;Paneth cells: 19.3;Salivary ionocytes: 18.5;Submucosal glandular cells: 27.2" "Cell type enhanced" "Detected in many" "lower rhombic lip: 13.1" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 28.8;Rectum Adenocarcinoma (TCGA): 23.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bile duct cancer: 8.5;colorectal cancer: 10.2;Gastric cancer: 7.6" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA071540 Enhanced NA NA "Cluster 64: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 3 "HPA071540: " "unprognostic (9.24e-2)" "unprognostic (1.53e-1)" "unprognostic (2.15e-1)" "unprognostic (1.31e-2)" "unprognostic (5.44e-1)" "unprognostic (4.55e-3)" "unprognostic (6.68e-2)" "unprognostic (8.99e-2)" "unprognostic (3.92e-2)" "unprognostic (4.94e-1)" "unprognostic (1.74e-1)" "unprognostic (2.00e-1)" "unprognostic (1.60e-2)" "unprognostic (4.08e-2)" "potential prognostic favorable (4.56e-4)" "unprognostic (7.75e-2)" NOXRED1 "C14orf148, FLJ32809" ENSG00000165555 "NADP dependent oxidoreductase domain containing 1" Q6NXP6 14 77394021-77423523 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "retina: 4.0;testis: 5.7" "Group enriched" "Detected in many" 4 "Early spermatids: 152.5;Late primary spermatocytes: 76.9;Late spermatids: 182.0" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA055658, HPA060408" Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 47: Testis - Mixed function" "Cluster 17: Choroid plexus - Cilium" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" Vesicles "Plasma membrane" "HPA055658: , HPA060408: " "unprognostic (2.51e-1)" NPAP1 C15orf2 ENSG00000185823 "Nuclear pore associated protein 1" Q9NZP6 15 24675775-24683393 "Human disease related genes, Predicted intracellular proteins, Transporters" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "testis: 2.8" "Cell type enhanced" "Detected in some" "Papillary tip epithelial cells: 3.5;Renal collecting duct intercalated cells: 4.4;Renal collecting duct principal cells: 11.7;Renal connecting tubule cells: 15.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Spermatocytes" "HPA018828, HPA019562" Uncertain Supported "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 67: Testis - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" Nucleoplasm "Vesicles, Plasma membrane" "HPA018828: , HPA019562: " "unprognostic (1.54e-2)" "unprognostic (5.99e-2)" NPAS1 "bHLHe11, MOP5, PASD5" ENSG00000130751 "Neuronal PAS domain protein 1" Q99742 19 47019837-47045775 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.4;skin 1: 7.6" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 18.5;Cone photoreceptor cells: 29.0;Foveolar cells: 44.8;Oocytes: 152.0" "Cell type enhanced" "Detected in many" "CGE interneuron: 71.4;MGE interneuron: 34.4" "Cancer enriched" "Detected in many" 4 "Testicular Germ Cell Tumor (TCGA): 13.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 13.5" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Kidney - Fibroblasts, Skin - Keratinocyte (granular), Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA043364, HPA072259" Approved Approved Nucleoplasm NA NA "Cluster 2: Non-specific - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 41: Oocytes - Oogenesis" 146 Nucleoplasm "HPA043364: , HPA072259: " "unprognostic (7.56e-2)" "unprognostic (5.50e-3)" "potential prognostic favorable (9.45e-4)" "unprognostic (3.37e-2)" "unprognostic (1.22e-1)" "unprognostic (4.40e-2)" "unprognostic (1.88e-1)" "unprognostic (4.12e-1)" "potential prognostic unfavorable (2.24e-5)" "potential prognostic unfavorable (1.01e-4)" "unprognostic (5.43e-2)" "unprognostic (1.94e-1)" "unprognostic (1.15e-1)" "unprognostic (7.84e-2)" "unprognostic (5.70e-2)" "unprognostic (4.23e-2)" "unprognostic (1.75e-1)" "unprognostic (6.79e-2)" "unprognostic (3.57e-2)" NPAS2 "bHLHe9, MOP4, PASD4" ENSG00000170485 "Neuronal PAS domain protein 2" Q99743 2 100820139-100996829 "Predicted intracellular proteins, Transcription factors" "Biological rhythms, DNA damage, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 780.5;Ocular epithelial cells: 354.3;Renal collecting duct principal cells: 340.7;Urothelial cells: 665.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA019674 Uncertain Supported Approved Nucleoplasm NA NA "Cluster 70: Non-specific - Protein processing" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 69: Urothelial cells - Basic cellular functions" 18 Nucleoplasm "HPA019674: " "unprognostic (1.60e-2)" "unprognostic (1.50e-1)" "potential prognostic favorable (3.65e-4)" "unprognostic (8.57e-3)" "unprognostic (2.67e-1)" "unprognostic (1.30e-2)" "unprognostic (2.23e-2)" "unprognostic (3.40e-3)" "unprognostic (2.29e-1)" "unprognostic (6.39e-2)" "unprognostic (1.03e-3)" "unprognostic (9.94e-2)" "unprognostic (2.39e-1)" "potential prognostic unfavorable (3.43e-5)" "unprognostic (2.05e-1)" "potential prognostic unfavorable (1.26e-4)" "unprognostic (5.25e-2)" "unprognostic (7.22e-2)" "unprognostic (1.27e-1)" "unprognostic (1.49e-1)" "unprognostic (2.39e-2)" "unprognostic (1.06e-2)" "unprognostic (4.07e-2)" "unprognostic (2.31e-1)" "unprognostic (9.53e-2)" "unprognostic (6.79e-2)" "unprognostic (2.07e-1)" "unprognostic (2.28e-1)" "unprognostic (1.26e-1)" "unprognostic (1.93e-3)" "unprognostic (1.22e-3)" NPAS3 "bHLHe12, MOP6, PASD6" ENSG00000151322 "Neuronal PAS domain protein 3" Q8IXF0 14 32934396-33820863 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 12.8;cervix: 5.7" "Cell type enhanced" "Detected in many" "Astrocytes: 5583.4;Bergmann glia: 7383.8;Ependymal cells: 4393.7;Oligodendrocyte progenitor cells: 3088.9;Oligodendrocytes: 2177.9;Pituicytes/FSCs: 1316.5;Pituitary stem cells: 1519.6;Podocytes: 4480.6" "Cell type enhanced" "Detected in all" "astrocyte: 6385.7;Bergmann glia: 7724.8" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 16.9;Ovary Serous Cystadenocarcinoma (TCGA): 8.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Pituitary gland - Undifferentiated cells (Pituitary gland), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075337 Enhanced Supported Nucleoplasm NA NA "Cluster 65: Brain - Transcription" "Cluster 39: Astrocytes - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 28: Astrocytes - Homeostasis & neuron support" 3 Nucleoplasm "HPA075337: " "unprognostic (5.12e-3)" "unprognostic (5.64e-2)" "unprognostic (1.83e-1)" "unprognostic (3.20e-2)" "unprognostic (9.96e-2)" "unprognostic (3.65e-2)" "unprognostic (2.10e-1)" "unprognostic (1.34e-2)" "unprognostic (4.32e-2)" "unprognostic (8.56e-2)" "unprognostic (2.67e-1)" "unprognostic (1.12e-1)" "unprognostic (7.64e-2)" "unprognostic (2.02e-1)" NPAS4 "bHLHe79, Le-PAS, NXF, PASD10" ENSG00000174576 "Neuronal PAS domain protein 4" Q8IUM7 11 66421004-66426707 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 18.6;pituitary gland: 20.0" "Cell type enhanced" "Detected in some" "Gonadotrophs: 11.4;Lactotrophs: 21.6;Other brain neurons: 3.0;Pancreatic islet cells: 11.1;Retinal amacrine cells: 22.3;Retinal ganglion cells: 7.7;Retinal horizontal cells: 6.0;Smooth muscle cells: 6.7;Thyrotrophs: 4.2" "Cell type enhanced" "Detected in many" "medium spiny neuron: 5.8" "Not detected" "Not detected" "Group enriched" "Detected in many" 13 "cerebellum: 368.0;cerebral cortex: 115.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Minor Salivary Gland - Smooth muscle cells, Prostate - Smooth muscle cells, Skin - Smooth muscle cells" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "basal ganglia: 6.5;cerebellum: 6.8;cerebral cortex: 9.9;hippocampal formation: 6.1;olfactory bulb: 5.1" "HPA039248, HPA039255" Uncertain Approved "Nucleoplasm,Nuclear membrane,Nuclear bodies,Vesicles" NA NA "Cluster 64: Non-specific - Transcription" "Cluster 35: Non-specific - DNA binding" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 3 "Nucleoplasm, Nuclear bodies" "Nuclear membrane, Vesicles" "HPA039248: , HPA039255: " NPAT "E14, p220" ENSG00000149308 "Nuclear protein, coactivator of histone transcription" Q14207 11 108157215-108222638 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045908, HPA066370" Enhanced "Nucleoplasm,Nuclear bodies" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 9: T-cells - Adaptive immunity: Regulation" 8 "Nucleoplasm, Nuclear bodies" "HPA045908: , HPA066370: " "unprognostic (6.22e-2)" "unprognostic (1.49e-1)" "unprognostic (1.21e-1)" "unprognostic (6.88e-2)" "unprognostic (3.62e-1)" "unprognostic (2.64e-1)" "unprognostic (6.71e-2)" "unprognostic (9.08e-2)" "unprognostic (2.11e-2)" "unprognostic (3.45e-2)" "potential prognostic favorable (2.79e-8)" "unprognostic (1.24e-3)" "unprognostic (7.00e-2)" "unprognostic (3.71e-2)" "unprognostic (6.05e-2)" "unprognostic (2.09e-1)" "unprognostic (4.49e-2)" "unprognostic (2.35e-2)" "unprognostic (9.27e-2)" "unprognostic (4.97e-2)" "unprognostic (2.09e-1)" "unprognostic (3.61e-2)" "unprognostic (7.04e-2)" "unprognostic (7.62e-2)" "unprognostic (9.79e-3)" "unprognostic (2.17e-1)" "unprognostic (1.41e-2)" "unprognostic (6.93e-2)" "unprognostic (4.66e-1)" "unprognostic (1.27e-1)" "unprognostic (2.48e-1)" NPB "PPL7, PPNPB" ENSG00000183979 "Neuropeptide B" Q8NG41 17 81900745-81902905 "Predicted secreted proteins" Neuropeptide "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "brain: 16.2" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 28.1;Early primary spermatocytes: 14.1;Epicardial cells: 13.6;Syncytiotrophoblasts: 160.9;Undifferentiated spermatogonia: 57.9" "Cell type enhanced" "Detected in many" "oligodendrocyte: 11.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 2.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted in other tissues" Neuropeptide NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" "unprognostic (9.34e-2)" "unprognostic (1.74e-2)" "unprognostic (8.56e-3)" "unprognostic (2.63e-1)" "potential prognostic favorable (1.81e-4)" "potential prognostic favorable (7.31e-4)" "unprognostic (8.10e-2)" "unprognostic (3.56e-2)" "unprognostic (3.53e-2)" "unprognostic (2.38e-1)" "unprognostic (1.06e-1)" "unprognostic (2.72e-1)" "unprognostic (4.08e-2)" "unprognostic (8.56e-2)" NPBWR1 GPR7 ENSG00000288611 "Neuropeptides B and W receptor 1" P48145 8 52939182-52943734 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.0;liver: 2.4" "Cell type enhanced" "Detected in some" "Cholangiocytes: 2.0;Hepatocytes: 1.2;Other brain neurons: 1.5;Respiratory basal cells: 2.4;Submucosal glandular cells: 1.2" "Cell type enhanced" "Detected in some" "CGE interneuron: 7.1;thalamic excitatory: 6.8;upper-layer intratelencephalic: 4.2" "Cancer enhanced" "Detected in some" "Lung Squamous Cell Carcinoma (TCGA): 2.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Pituitary gland - Lactotropes, Prostate - Urothelial cells" "Low region specificity" "Detected in some" "Region enhanced" "Detected in many" "cerebral cortex: 11.0" NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 1 "unprognostic (1.81e-1)" "unprognostic (1.72e-2)" "unprognostic (1.59e-1)" "unprognostic (1.61e-1)" "unprognostic (2.76e-1)" NPBWR2 GPR8 ENSG00000125522 "Neuropeptides B and W receptor 2" P48146 20 64103802-64107565 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "cerebral cortex: 5.8;white matter: 2.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adrenal gland - Adrenal medulla cells" "Region enhanced" "Detected in single" "olfactory bulb: 1.1" NA NA "Cluster 53: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" 15 NPC1 SLC65A1 ENSG00000141458 "NPC intracellular cholesterol transporter 1" O15118 18 23506184-23586506 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Cholesterol metabolism, Host-virus interaction, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" "Host cell receptor for virus entry, Receptor" "Disease variant, Niemann-Pick disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 534.3;Endometrial glandular cells: 507.9;Epididymal basal cells: 434.1;Urothelial cells: 486.0" "Cell type enhanced" "Detected in all" "oligodendrocyte: 332.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 71.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026618, CAB070132" Approved NA NA 8000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 38 "CAB070132: , HPA026618: " "potential prognostic unfavorable (7.05e-4)" "unprognostic (8.78e-2)" "unprognostic (2.87e-2)" "unprognostic (6.99e-3)" "unprognostic (5.35e-2)" "unprognostic (8.66e-2)" "unprognostic (2.93e-2)" "unprognostic (1.08e-1)" "unprognostic (1.97e-1)" "unprognostic (3.44e-2)" "unprognostic (9.00e-2)" "unprognostic (4.17e-2)" "unprognostic (9.84e-2)" "validated prognostic unfavorable (8.00e-8)" "validated prognostic unfavorable (6.88e-5)" "unprognostic (2.49e-1)" "unprognostic (1.72e-2)" "unprognostic (3.42e-2)" "unprognostic (4.73e-2)" "unprognostic (2.19e-2)" "unprognostic (9.81e-2)" "unprognostic (7.55e-3)" "unprognostic (1.94e-2)" "unprognostic (1.38e-3)" "unprognostic (2.44e-1)" "unprognostic (1.30e-1)" "unprognostic (1.17e-2)" "unprognostic (1.76e-1)" "unprognostic (4.59e-2)" "unprognostic (1.07e-1)" "unprognostic (1.16e-3)" NPC1L1 SLC65A2 ENSG00000015520 "NPC1 like intracellular cholesterol transporter 1" Q9UHC9 7 44512535-44541330 "FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "intestine: 51.0;liver: 46.6" "Cell type enhanced" "Detected in some" "Cholangiocytes: 11.2;Early spermatids: 45.4;Gastric progenitor cells: 14.1;Hepatocytes: 43.9;Late spermatids: 9.3;Neuroendocrine cells: 6.3;Pancreatic islet cells: 14.7" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "Liver Hepatocellular Carcinoma (TCGA): 10.5;Pancreatic Adenocarcinoma (TCGA): 11.4;Stomach Adenocarcinoma (TCGA): 7.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Gastric cancer: 9.2;liver cancer: 7.6" "Kidney - Proximal tubular cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB070127, CAB070128" Enhanced NA NA "Cluster 77: Intestine - Digestion" "Cluster 37: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" "CAB070127: , CAB070128: " "unprognostic (6.94e-2)" "unprognostic (4.22e-2)" "unprognostic (8.97e-2)" "unprognostic (2.32e-3)" "potential prognostic unfavorable (7.13e-5)" "unprognostic (7.74e-2)" "unprognostic (1.94e-1)" "unprognostic (1.16e-1)" "unprognostic (6.31e-3)" "unprognostic (7.01e-2)" "unprognostic (2.43e-1)" "unprognostic (2.91e-1)" "unprognostic (2.54e-1)" "unprognostic (1.46e-2)" "unprognostic (2.66e-1)" NPC2 "EDDM1, HE1, NP-C2" ENSG00000119655 "NPC intracellular cholesterol transporter 2" P61916 14 74476192-74494177 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" "Disease variant, Niemann-Pick disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "epididymis: 15839.4" "Cell type enriched" "Detected in all" 14 "Epididymal principal cells: 47512.0" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 107.1;choroid plexus epithelial cell: 118.0" "Cancer enhanced" "Detected in all" "Thyroid Carcinoma (TCGA): 4543.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 671.5;classical monocyte: 1304.7;intermediate monocyte: 1776.9;myeloid DC: 588.8;neutrophil: 678.2;non-classical monocyte: 1258.0;plasmacytoid DC: 2119.0" "Group enriched" "Detected in all" 5 "dendritic cells: 2119.0;granulocytes: 678.2;monocytes: 1776.9" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Minor Salivary Gland - Macrophages, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000835, CAB032888" Enhanced "Secreted to blood" Transport NA NA 14000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 21: Non-specific - Metabolism" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 11 "CAB032888: , HPA000835: " "unprognostic (1.44e-1)" "unprognostic (2.61e-3)" "unprognostic (2.68e-1)" "unprognostic (4.09e-2)" "unprognostic (4.57e-2)" "unprognostic (1.42e-3)" "unprognostic (3.05e-3)" "unprognostic (8.59e-2)" "unprognostic (4.89e-2)" "unprognostic (1.03e-1)" "potential prognostic favorable (5.11e-5)" "unprognostic (3.47e-1)" "unprognostic (3.57e-2)" "potential prognostic unfavorable (2.36e-5)" "unprognostic (4.88e-2)" "potential prognostic favorable (9.10e-4)" "unprognostic (2.83e-1)" "unprognostic (7.52e-3)" "potential prognostic unfavorable (2.55e-4)" "unprognostic (1.28e-3)" "unprognostic (5.51e-2)" "unprognostic (1.34e-1)" "unprognostic (1.01e-1)" "unprognostic (5.80e-2)" "unprognostic (5.99e-3)" "unprognostic (8.28e-2)" "unprognostic (1.33e-1)" "unprognostic (1.65e-3)" "unprognostic (1.94e-1)" "unprognostic (1.46e-3)" "unprognostic (1.22e-1)" NPDC1 "CAB-, CAB1, DKFZp586J0523" ENSG00000107281 "Neural proliferation, differentiation and control 1" Q9NQX5 9 137039463-137046179 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 84.0;Gastric chief cells: 103.7;Goblet cells: 46.5;Mucous neck cells: 81.5;Prostatic club cells: 42.2;Prostatic glandular cells: 73.7;Vascular endothelial cells: 69.4" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 359.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 12.3;MAIT T-cell: 14.7;memory CD4 T-cell: 19.1;memory CD8 T-cell: 18.9;T-reg: 15.9" "Lineage enriched" "Detected in many" 5 "T-cells: 19.1" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008189 Approved Approved Nucleoplasm,Cytosol NA NA 250000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 64: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 34 Nucleoplasm Cytosol "HPA008189: " "unprognostic (4.55e-2)" "unprognostic (4.12e-2)" "unprognostic (1.29e-1)" "unprognostic (2.65e-2)" "potential prognostic unfavorable (4.38e-4)" "unprognostic (2.36e-1)" "unprognostic (1.39e-1)" "unprognostic (3.00e-3)" "potential prognostic unfavorable (2.31e-4)" "unprognostic (2.54e-1)" "unprognostic (8.19e-2)" "unprognostic (8.05e-3)" "unprognostic (1.84e-1)" "unprognostic (1.17e-1)" "potential prognostic favorable (2.46e-4)" "unprognostic (1.04e-1)" "unprognostic (1.60e-1)" "unprognostic (1.86e-2)" "unprognostic (1.41e-1)" "unprognostic (3.68e-1)" "unprognostic (1.16e-1)" "potential prognostic favorable (4.89e-4)" "unprognostic (2.98e-2)" "unprognostic (2.53e-1)" "unprognostic (1.71e-1)" "unprognostic (1.27e-3)" "unprognostic (3.44e-1)" "unprognostic (4.14e-3)" "unprognostic (1.21e-1)" "unprognostic (7.39e-2)" "unprognostic (1.15e-2)" NPEPL1 "bA261P9.2, FLJ11583" ENSG00000215440 "Aminopeptidase like 1" Q8NDH3 20 58689131-58719238 "Enzymes, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 51.7;Bergmann glia: 60.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 23.9;classical monocyte: 18.5;eosinophil: 7.2;intermediate monocyte: 13.0;myeloid DC: 11.4;neutrophil: 13.7;non-classical monocyte: 18.9" "Group enriched" "Detected in all" 5 "dendritic cells: 11.4;granulocytes: 23.9;monocytes: 18.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004986, CAB017025, HPA036356" Approved Approved Nucleoplasm,Cytosol NA NA 8700 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 24: Non-specific - Transcription" "Cluster 54: Immune cells - T cell receptor" "Cluster 15: Kidney cancer - Membrane components" "Cluster 35: Neurons - Synaptic function & neurogenesis" Nucleoplasm Cytosol "CAB004986: , CAB017025: , HPA036356: " "unprognostic (4.64e-2)" "unprognostic (1.30e-1)" "unprognostic (1.88e-1)" "unprognostic (1.70e-1)" "unprognostic (1.20e-1)" "unprognostic (1.46e-1)" "unprognostic (8.14e-3)" "unprognostic (1.93e-1)" "unprognostic (4.90e-2)" "unprognostic (4.83e-1)" "potential prognostic unfavorable (8.45e-8)" "unprognostic (4.85e-3)" "potential prognostic favorable (2.11e-4)" "unprognostic (8.93e-3)" "unprognostic (3.66e-1)" "unprognostic (8.28e-3)" "unprognostic (4.06e-1)" "unprognostic (2.05e-1)" "unprognostic (1.65e-1)" "unprognostic (2.54e-2)" "unprognostic (1.78e-2)" "unprognostic (4.19e-2)" "unprognostic (3.50e-3)" "unprognostic (4.77e-2)" "unprognostic (1.20e-2)" "potential prognostic favorable (3.80e-5)" "unprognostic (1.42e-2)" "unprognostic (4.73e-2)" "unprognostic (2.65e-1)" "unprognostic (1.13e-1)" "unprognostic (5.35e-1)" NPEPPS "MP100, PSA" ENSG00000141279 "Aminopeptidase puromycin sensitive" P55786 17 47522942-47624665 "Enzymes, Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1612.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021453, HPA045649" Uncertain Supported Cytosol No No 4300000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 24: Neutrophils - Innate immunity signal integration" 12 Cytosol "HPA021453: , HPA045649: " "unprognostic (2.51e-2)" "unprognostic (2.16e-1)" "unprognostic (4.68e-2)" "unprognostic (6.69e-3)" "potential prognostic favorable (3.84e-4)" "unprognostic (1.75e-1)" "unprognostic (3.12e-1)" "unprognostic (1.64e-1)" "unprognostic (6.43e-2)" "potential prognostic unfavorable (2.99e-6)" "potential prognostic favorable (1.45e-5)" "unprognostic (1.07e-2)" "unprognostic (1.61e-2)" "potential prognostic unfavorable (7.82e-5)" "unprognostic (4.06e-3)" "unprognostic (2.80e-2)" "unprognostic (2.66e-3)" "unprognostic (3.62e-2)" "unprognostic (3.80e-1)" "unprognostic (4.76e-2)" "unprognostic (5.44e-3)" "unprognostic (5.80e-3)" "potential prognostic unfavorable (1.07e-4)" "unprognostic (4.10e-2)" "unprognostic (1.88e-2)" "unprognostic (4.07e-1)" "unprognostic (1.57e-1)" "unprognostic (6.63e-2)" "unprognostic (4.43e-2)" "unprognostic (8.64e-3)" "unprognostic (1.64e-1)" NPFF FMRFAL ENSG00000139574 "Neuropeptide FF-amide peptide precursor" O15130 12 53506688-53507484 "Predicted secreted proteins" Neuropeptide "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 454 "epididymis: 1489.7" "Cell type enriched" "Detected in some" 58 "Epididymal principal cells: 840.0" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in some" 7 "Testicular Germ Cell Tumor (TCGA): 14.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "Rhabdoid: 4.3" "Colon - Enteric glia cells" "Region enriched" "Detected in some" 7 "pons and medulla: 11.4" "Region enriched" "Detected in all" 6 "cerebellum: 30.3" "Secreted in male reproductive system" Neuropeptide NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 43: Hindbrain - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" "unprognostic (3.76e-1)" "unprognostic (8.36e-2)" "unprognostic (9.11e-2)" "unprognostic (2.21e-1)" "unprognostic (2.12e-2)" "unprognostic (5.31e-3)" "unprognostic (1.65e-1)" "unprognostic (1.56e-1)" NPFFR1 "GPR147, NPFF1R1, OT7T022" ENSG00000148734 "Neuropeptide FF receptor 1" Q9GZQ6 10 70247329-70284004 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 5.5;retina: 2.8" "Cell type enhanced" "Detected in some" "Astrocytes: 20.5;Bergmann glia: 54.8;Brain excitatory neurons: 10.2;Ependymal cells: 9.8;Müller glia: 22.0;Other brain neurons: 10.3;Podocytes: 6.7;Retinal pigment epithelial cells: 29.8;Schwann cells: 7.2" "Cell type enhanced" "Detected in many" "Bergmann glia: 50.5;mammillary body: 34.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Testis - Sertoli cells" "Group enriched" "Detected in many" 5 "basal ganglia: 15.7;hypothalamus: 6.3" "Low region specificity" "Detected in some" HPA037521 Uncertain NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 25: Non-specific - Transcription" "Cluster 32: Non-specific - Cell proliferation" "Cluster 98: Neurons - Neurotransmission & signaling" 2 "HPA037521: " "unprognostic (6.51e-2)" "unprognostic (2.88e-1)" "unprognostic (4.17e-3)" "unprognostic (1.70e-1)" NPFFR2 "GPR74, NPFF2, NPGPR" ENSG00000056291 "Neuropeptide FF receptor 2" Q9Y5X5 4 72031902-72148305 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 6.7;seminal vesicle: 3.0" "Cell type enriched" "Detected in some" 9 "Breast lactating cells: 379.6" "Cell type enriched" "Detected in many" 4 "eccentric medium spiny neuron: 296.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 14.7" "Adipose visceral - Mesothelial cells" "Region enriched" "Detected in some" 4 "olfactory bulb: 4.3" "Low region specificity" "Detected in all" HPA026825 Approved "Plasma membrane,Actin filaments" NA NA "Cluster 80: Thymus - Adaptive immune response" "Cluster 14: Neurons - Synaptic function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 4: Breast lactating luminal cells - Lactation" "Plasma membrane" "Actin filaments" "HPA026825: " "unprognostic (5.14e-3)" "unprognostic (2.47e-1)" "unprognostic (2.11e-2)" "unprognostic (1.34e-1)" NPHP1 "JBTS4, NPH1, SLSN1" ENSG00000144061 "Nephrocystin 1" O15259 2 110122311-110205066 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Differentiation, Spermatogenesis" "Ciliopathy, Disease variant, Joubert syndrome, Leber congenital amaurosis, Nephronophthisis, Senior-Loken syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 36.0;skeletal muscle: 34.0" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 215.2;Endometrial ciliated cells: 239.5;Ependymal cells: 312.7;Epididymal efferent duct ciliated cells: 144.0;Fallopian tube ciliated cells: 230.3;Late primary spermatocytes: 289.2;Myonuclei: 568.1;Respiratory ciliated cells: 338.5" "Cell type enhanced" "Detected in all" "ependymal cell: 340.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 1.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046093, HPA074071" Approved NA NA "Cluster 24: Non-specific - Transcription" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 17 "HPA046093: , HPA074071: " "unprognostic (1.13e-1)" "unprognostic (5.06e-2)" "unprognostic (1.76e-1)" "unprognostic (2.62e-2)" "unprognostic (1.10e-1)" "unprognostic (1.90e-2)" "unprognostic (1.04e-2)" "unprognostic (1.73e-1)" "unprognostic (1.45e-2)" "unprognostic (7.78e-2)" "potential prognostic favorable (2.59e-4)" "unprognostic (1.55e-2)" "unprognostic (2.01e-2)" "potential prognostic unfavorable (1.92e-4)" "unprognostic (1.42e-1)" "unprognostic (5.55e-2)" "unprognostic (9.44e-2)" "unprognostic (3.81e-2)" "unprognostic (2.96e-1)" "unprognostic (4.39e-2)" "unprognostic (2.55e-1)" "unprognostic (1.72e-1)" "unprognostic (1.44e-3)" "unprognostic (1.30e-2)" "unprognostic (1.34e-1)" "unprognostic (6.90e-2)" "unprognostic (3.60e-2)" "unprognostic (1.45e-2)" "unprognostic (7.26e-3)" "unprognostic (1.92e-1)" "unprognostic (2.49e-1)" NPHP3 "CFAP31, FLJ30691, FLJ36696, KIAA2000, MKS7, NPH3, SLSN3" ENSG00000113971 "Nephrocystin 3" Q7Z494 3 132680609-132722432 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Wnt signaling pathway" "Ciliopathy, Disease variant, Meckel syndrome, Nephronophthisis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Astrocytes: 101.1;Bergmann glia: 97.5;Brain excitatory neurons: 35.5;Brain inhibitory neurons: 42.1;Choroid plexus epithelial cells: 83.8;Ependymal cells: 73.3;Microglia: 69.3;Oligodendrocyte progenitor cells: 79.0;Oligodendrocytes: 139.8;Other brain neurons: 43.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA009150 Uncertain Approved "Nucleoplasm,Nucleoli,Vesicles,Primary cilium,Primary cilium tip,Cytosol" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 75: Ovary - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 56: Non-specific - Sensory perception" "Cluster 22: Non-specific - Basic cellular functions" 8 "Nucleoli, Primary cilium" "Nucleoplasm, Vesicles, Primary cilium tip, Cytosol" "HPA009150: " "unprognostic (2.29e-2)" "unprognostic (5.27e-2)" "unprognostic (1.08e-1)" "unprognostic (2.08e-2)" "unprognostic (2.42e-2)" "unprognostic (1.59e-1)" "unprognostic (4.35e-1)" "unprognostic (5.74e-2)" "unprognostic (5.46e-2)" "unprognostic (6.34e-2)" "unprognostic (3.10e-1)" "unprognostic (1.49e-1)" "unprognostic (8.04e-2)" "potential prognostic unfavorable (3.22e-4)" "unprognostic (4.17e-2)" "unprognostic (2.42e-2)" "unprognostic (3.52e-1)" "unprognostic (1.86e-1)" "unprognostic (5.52e-2)" "unprognostic (2.79e-2)" "unprognostic (4.65e-2)" "unprognostic (1.87e-1)" "unprognostic (2.78e-3)" "unprognostic (2.75e-1)" "unprognostic (1.45e-1)" "unprognostic (1.06e-1)" "unprognostic (4.75e-2)" "unprognostic (2.61e-2)" "unprognostic (8.89e-2)" "unprognostic (2.86e-1)" "unprognostic (4.71e-2)" NPHP3-ACAD11 ENSG00000274810 "NPHP3-ACAD11 readthrough (NMD candidate)" 3 132558142-132722459 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Cardiomyocytes: 410.1;Epicardial cells: 120.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 11: White matter - Signal transduction" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "unprognostic (2.21e-1)" "unprognostic (1.83e-3)" "unprognostic (3.26e-3)" "unprognostic (1.75e-1)" "unprognostic (1.34e-2)" "unprognostic (2.72e-1)" "unprognostic (2.00e-1)" "unprognostic (3.31e-2)" "unprognostic (2.16e-1)" "unprognostic (3.03e-1)" "unprognostic (2.93e-2)" "unprognostic (1.67e-1)" "unprognostic (1.27e-1)" "unprognostic (2.97e-3)" NPHP4 "KIAA0673, POC10, SLSN4" ENSG00000131697 "Nephrocystin 4" O75161 1 5862811-5992473 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ciliopathy, Disease variant, Leber congenital amaurosis, Nephronophthisis, Senior-Loken syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Corticotrophs: 84.2;Ependymal cells: 85.4;Gonadotrophs: 100.2;Lactotrophs: 90.6;Somatotrophs: 79.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Pituitary gland - Corticotropes, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063852, HPA065526" Approved Approved "Nucleoplasm,Nuclear bodies,Vesicles,Cytosol" NA NA "Cluster 21: Testis - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 23 Nucleoplasm "Nuclear bodies, Vesicles, Cytosol" "HPA063852: , HPA065526: " "unprognostic (7.14e-3)" "unprognostic (5.67e-2)" "unprognostic (2.42e-1)" "unprognostic (3.29e-2)" "unprognostic (4.86e-2)" "unprognostic (1.75e-1)" "unprognostic (1.51e-1)" "unprognostic (2.89e-3)" "unprognostic (1.56e-2)" "potential prognostic favorable (3.10e-5)" "unprognostic (1.05e-1)" "unprognostic (1.28e-2)" "unprognostic (1.05e-2)" "unprognostic (2.51e-1)" "unprognostic (3.51e-2)" "unprognostic (9.62e-3)" "unprognostic (2.21e-1)" "unprognostic (1.79e-2)" "potential prognostic favorable (7.98e-4)" "unprognostic (1.85e-1)" "unprognostic (1.08e-2)" "unprognostic (3.77e-1)" "unprognostic (1.69e-1)" "unprognostic (2.48e-3)" "unprognostic (2.66e-2)" "unprognostic (6.11e-2)" "unprognostic (3.38e-1)" "unprognostic (1.11e-1)" "unprognostic (7.59e-2)" NPHS1 "CNF, NPHN" ENSG00000161270 "NPHS1 adhesion molecule, nephrin" O60500 19 35825372-35869287 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Myogenesis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "kidney: 39.8;pancreas: 21.5" "Cell type enriched" "Detected in many" 7 "Podocytes: 1832.8" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells, Kidney - Podocytes, Stomach - Gastric enteroendocrine cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB035555 Enhanced NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 6: Non-specific - Immune response" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 57: Podocytes - Glomerular filtration" 8 "CAB035555: " NPHS2 "PDCN, SRN1" ENSG00000116218 "NPHS2 stomatin family member, podocin" Q9NP85 1 179550539-179575952 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 145 "kidney: 244.9" "Cell type enriched" "Detected in some" 122 "Podocytes: 2016.5" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 2.2;ependymal cell: 1.5" "Cancer enhanced" "Detected in single" "Kidney Renal Clear Cell Carcinoma (TCGA): 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Podocytes, Stomach - Gastric mucous cells, Testis - Late spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "CAB037267, HPA049486" Enhanced NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 57: Podocytes - Glomerular filtration" 3 "CAB037267: , HPA049486: " "unprognostic (1.58e-1)" "unprognostic (8.94e-2)" NPIPA1 "morpheus, NPIP" ENSG00000183426 "Nuclear pore complex interacting protein family member A1" Q9UND3 16 14922802-14952060 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 352.2" "Cell type enhanced" "Detected in some" "Astrocytes: 34.8;Bergmann glia: 31.5;Brain excitatory neurons: 44.5;Brain inhibitory neurons: 28.9;Early spermatids: 46.5;Ependymal cells: 44.2;Oligodendrocyte progenitor cells: 33.2;Oligodendrocytes: 21.5;Other brain neurons: 22.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" HPA053611 Supported Approved Nucleoplasm NA NA "Cluster 32: Basophils - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" Nucleoplasm "HPA053611: " "unprognostic (1.87e-2)" "unprognostic (3.16e-1)" "unprognostic (5.17e-2)" "unprognostic (3.33e-3)" "unprognostic (1.22e-2)" "unprognostic (5.58e-2)" "unprognostic (1.81e-1)" "unprognostic (1.11e-1)" "unprognostic (4.89e-2)" "potential prognostic unfavorable (4.39e-5)" "unprognostic (1.09e-1)" "unprognostic (1.53e-1)" "unprognostic (3.45e-1)" "potential prognostic favorable (1.87e-4)" "unprognostic (1.57e-1)" "unprognostic (7.28e-2)" "unprognostic (1.11e-2)" "unprognostic (1.75e-2)" "unprognostic (1.25e-1)" "unprognostic (1.91e-1)" "unprognostic (1.71e-3)" "unprognostic (1.01e-1)" "unprognostic (4.34e-2)" "unprognostic (2.52e-1)" "unprognostic (2.85e-1)" "unprognostic (1.20e-1)" "unprognostic (1.55e-1)" "unprognostic (1.58e-3)" "unprognostic (1.47e-1)" NPIPA2 ENSG00000254852 "Nuclear pore complex interacting protein family member A2" E9PIF3 16 14742533-14765462 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 22.2" "Cell type enhanced" "Detected in single" "Podocytes: 1.0" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "Testicular Germ Cell Tumor (TCGA): 2.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" HPA053611 Approved Approved Nucleoplasm NA NA "Cluster 64: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 5: Rhabdoid - Unknown function" "Cluster 102: Non-specific - Mixed function" Nucleoplasm "HPA053611: " "unprognostic (3.13e-2)" "unprognostic (1.19e-1)" "unprognostic (4.31e-2)" "unprognostic (1.30e-2)" "unprognostic (1.33e-1)" NPIPA3 ENSG00000224712 "Nuclear pore complex interacting protein family member A3" F8WFD2 16 14703411-14726342 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 25.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" HPA053611 Approved Approved Nucleoplasm NA NA "Cluster 64: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 13: Non-specific - Mixed function" "Cluster 105: Non-specific - Mixed function" Nucleoplasm "HPA053611: " "unprognostic (7.59e-2)" "unprognostic (7.54e-3)" "unprognostic (2.71e-1)" "unprognostic (5.72e-3)" "unprognostic (1.43e-1)" NPIPA5 ENSG00000183793 "Nuclear pore complex interacting protein family member A5" E9PKD4 16 15363628-15381047 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "brain: 160.4" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 1.2;Distal convoluted tubule cells: 2.7;Loop of henle epithelial cells: 2.4;Myonuclei: 1.3;Oligodendrocyte progenitor cells: 1.0;Oligodendrocytes: 1.1;Papillary tip epithelial cells: 2.2;Podocytes: 1.8;Proximal tubule cells: 2.4;Renal collecting duct intercalated cells: 1.1;Renal collecting duct principal cells: 2.1;Renal connecting tubule cells: 2.2;Thyrotrophs: 1.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" HPA053611 Approved Approved Nucleoplasm NA NA "Cluster 64: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 54: Non-specific - Transcription" "Cluster 105: Non-specific - Mixed function" Nucleoplasm "HPA053611: " "unprognostic (4.06e-1)" "unprognostic (1.53e-1)" "unprognostic (1.20e-2)" "unprognostic (2.62e-1)" "unprognostic (9.48e-3)" "unprognostic (2.20e-2)" "unprognostic (7.70e-2)" "unprognostic (6.47e-3)" "unprognostic (2.90e-1)" "unprognostic (2.98e-1)" "unprognostic (1.18e-2)" "unprognostic (2.18e-1)" "unprognostic (5.97e-1)" "unprognostic (2.93e-1)" "unprognostic (5.12e-3)" "unprognostic (8.99e-3)" "unprognostic (7.76e-2)" "unprognostic (1.28e-1)" "unprognostic (1.00e-1)" "unprognostic (2.80e-1)" "unprognostic (2.53e-1)" "unprognostic (4.90e-3)" "unprognostic (4.01e-1)" "unprognostic (2.22e-1)" "unprognostic (1.30e-2)" "unprognostic (1.01e-2)" "unprognostic (3.46e-2)" "unprognostic (2.42e-2)" NPIPA7 ENSG00000214967 "Nuclear pore complex interacting protein family member A7" E9PJI5 16 16379140-16393972 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pituitary gland: 75.9" "Cell type enhanced" "Detected in some" "Astrocytes: 1.1;Bergmann glia: 1.1;Brain excitatory neurons: 2.0;Brain inhibitory neurons: 1.0;Choroid plexus epithelial cells: 1.6;Distal convoluted tubule cells: 1.3;Ependymal cells: 1.6;Microglia: 1.3;Oligodendrocyte progenitor cells: 1.0;Renal connecting tubule cells: 1.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" HPA053611 Approved Approved Nucleoplasm NA NA "Cluster 20: Pituitary gland - Hormone signaling" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 49: HMC-1 - Innate immune response" "Cluster 102: Non-specific - Mixed function" 2 Nucleoplasm "HPA053611: " "unprognostic (2.49e-2)" "unprognostic (1.89e-1)" "unprognostic (3.22e-3)" "unprognostic (2.35e-2)" "unprognostic (1.27e-1)" "unprognostic (1.22e-1)" "unprognostic (7.75e-2)" "unprognostic (3.07e-1)" "potential prognostic unfavorable (3.96e-6)" "unprognostic (4.13e-2)" "unprognostic (1.15e-1)" "unprognostic (2.53e-2)" "unprognostic (6.88e-2)" "unprognostic (5.94e-2)" "unprognostic (4.53e-3)" "unprognostic (1.33e-3)" "unprognostic (3.35e-1)" "unprognostic (9.65e-2)" "unprognostic (1.86e-3)" "unprognostic (1.97e-3)" "unprognostic (7.92e-3)" "unprognostic (2.74e-1)" "unprognostic (5.47e-2)" "unprognostic (7.04e-3)" "unprognostic (1.57e-1)" "unprognostic (1.52e-1)" "unprognostic (1.37e-2)" "unprognostic (2.07e-1)" NPIPA8 LCR16a9 ENSG00000214940 "Nuclear pore complex interacting protein family member A8" P0DM63 16 18317919-18336736 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 96.1" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 1.5;Loop of henle epithelial cells: 2.3;Papillary tip epithelial cells: 2.9;Podocytes: 2.3;Proximal tubule cells: 1.7;Renal collecting duct principal cells: 1.9;Renal connecting tubule cells: 2.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 41.0" HPA053611 Approved Approved Nucleoplasm NA NA "Cluster 64: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 105: Non-specific - Mixed function" Nucleoplasm "HPA053611: " "unprognostic (9.69e-2)" "unprognostic (2.93e-2)" "unprognostic (2.08e-3)" "unprognostic (2.07e-1)" "unprognostic (1.76e-1)" "unprognostic (2.24e-2)" "unprognostic (7.04e-3)" "unprognostic (2.31e-1)" "unprognostic (6.83e-2)" "unprognostic (1.60e-1)" "unprognostic (5.42e-2)" "unprognostic (6.55e-2)" "unprognostic (9.05e-2)" "unprognostic (4.41e-1)" "unprognostic (2.21e-2)" "unprognostic (2.12e-1)" "unprognostic (2.10e-2)" "unprognostic (9.32e-2)" "unprognostic (1.84e-2)" "unprognostic (1.62e-1)" "unprognostic (2.69e-1)" "unprognostic (2.60e-1)" "unprognostic (2.27e-1)" "unprognostic (7.79e-2)" "unprognostic (2.02e-1)" "unprognostic (1.10e-2)" "unprognostic (2.85e-1)" NPIPA9 ENSG00000183889 "Nuclear pore complex interacting protein family, member A9" 16 16317444-16350590 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Tissue enhanced" "Detected in all" "brain: 545.9" "Cell type enhanced" "Detected in some" "Fibro-adipogenic progenitors: 2.1;Leydig cells: 2.5;Megakaryocyte progenitors: 2.2;Myonuclei: 3.4;Myosatellite cells: 3.3;Respiratory ionocytes: 2.5;Retinal ganglion cells: 3.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" HPA053611 Approved Approved Nucleoplasm NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 64: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 49: HMC-1 - Innate immune response" "Cluster 7: Non-specific - Transcription" Nucleoplasm "HPA053611: " "unprognostic (2.22e-2)" "unprognostic (1.86e-1)" "unprognostic (3.47e-3)" "unprognostic (2.77e-1)" "unprognostic (3.42e-2)" "unprognostic (3.31e-1)" "unprognostic (2.47e-2)" "unprognostic (3.19e-1)" "potential prognostic unfavorable (3.84e-7)" "unprognostic (2.53e-2)" "unprognostic (2.30e-1)" "unprognostic (2.03e-3)" "unprognostic (4.53e-2)" "unprognostic (6.15e-2)" "unprognostic (2.93e-3)" "unprognostic (8.95e-3)" "unprognostic (2.92e-1)" "potential prognostic favorable (1.56e-4)" "unprognostic (1.09e-3)" "unprognostic (5.73e-2)" "unprognostic (1.16e-1)" "unprognostic (4.05e-2)" "unprognostic (9.24e-2)" "unprognostic (3.59e-2)" "unprognostic (6.35e-3)" "unprognostic (1.14e-1)" "unprognostic (4.29e-1)" "unprognostic (1.55e-1)" NPIPA9 ENSG00000233024 "Nuclear pore complex interacting protein family, member A9" 16 18358086-18379331 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Tissue enhanced" "Detected in all" "brain: 597.3" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 2.0;Distal convoluted tubule cells: 1.0;Myonuclei: 1.6;Podocytes: 2.3;Renal collecting duct intercalated cells: 1.2;Thymocytes: 1.7" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.4" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" HPA053611 Approved Approved Nucleoplasm NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 64: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 54: Non-specific - Transcription" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" Nucleoplasm "HPA053611: " "unprognostic (2.32e-2)" "unprognostic (2.64e-1)" "unprognostic (6.05e-3)" "unprognostic (2.36e-2)" "unprognostic (4.69e-2)" "unprognostic (3.44e-1)" "unprognostic (3.40e-2)" "unprognostic (4.53e-1)" "potential prognostic unfavorable (1.32e-4)" "unprognostic (9.78e-2)" "unprognostic (1.57e-1)" "unprognostic (6.62e-3)" "unprognostic (9.15e-2)" "unprognostic (7.20e-2)" "unprognostic (1.31e-3)" "unprognostic (1.08e-2)" "unprognostic (2.59e-1)" "unprognostic (8.62e-3)" "unprognostic (4.95e-3)" "unprognostic (1.31e-2)" "unprognostic (8.49e-2)" "unprognostic (6.12e-3)" "potential prognostic favorable (8.35e-4)" "unprognostic (3.07e-2)" "unprognostic (3.55e-1)" "unprognostic (2.71e-1)" "unprognostic (3.80e-2)" "unprognostic (1.12e-1)" NPIPB11 ENSG00000254206 "Nuclear pore complex interacting protein family member B11" E5RHQ5 16 29381310-29406711 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 128.7;Epicardial cells: 34.1;Retinal horizontal cells: 42.1;Retinal pigment epithelial cells: 46.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" HPA053611 Approved Approved Nucleoplasm NA NA "Cluster 64: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 56: Non-specific - Sensory perception" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" Nucleoplasm "HPA053611: " "unprognostic (9.21e-2)" "unprognostic (1.19e-1)" "unprognostic (1.11e-3)" "unprognostic (2.88e-2)" "unprognostic (2.68e-1)" "unprognostic (2.03e-2)" "unprognostic (2.36e-1)" "potential prognostic unfavorable (2.49e-6)" "unprognostic (3.17e-1)" "unprognostic (1.35e-2)" "unprognostic (7.63e-2)" "unprognostic (4.59e-1)" "unprognostic (8.32e-3)" "unprognostic (2.75e-2)" "unprognostic (1.41e-1)" "unprognostic (8.57e-3)" "unprognostic (6.80e-3)" "potential prognostic unfavorable (3.28e-4)" "unprognostic (2.10e-2)" "unprognostic (9.46e-2)" "unprognostic (2.86e-1)" "unprognostic (2.02e-2)" "unprognostic (1.30e-1)" "unprognostic (1.50e-1)" "unprognostic (4.32e-2)" NPIPB12 ENSG00000169203 "Nuclear pore complex interacting protein family member B12" F8W0I5 16 29483534-29506408 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 6 "Distal convoluted tubule cells: 3.9;Loop of henle epithelial cells: 2.5;Papillary tip epithelial cells: 2.2;Podocytes: 1.8;Proximal tubule cells: 4.2;Renal collecting duct intercalated cells: 2.8;Renal collecting duct principal cells: 2.0;Renal connecting tubule cells: 2.9" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebral cortex: 30.5" "Immune cell enhanced" "Detected in single" "NK-cell: 1.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" HPA053611 Approved Approved Nucleoplasm NA NA "Cluster 64: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 56: Non-specific - Sensory perception" "Cluster 105: Non-specific - Mixed function" Nucleoplasm "HPA053611: " "unprognostic (1.99e-2)" "unprognostic (4.38e-2)" "unprognostic (1.18e-2)" "unprognostic (6.96e-3)" "unprognostic (1.26e-1)" "unprognostic (1.85e-1)" "unprognostic (9.67e-2)" "unprognostic (3.85e-2)" "unprognostic (9.25e-2)" "potential prognostic unfavorable (1.16e-5)" "unprognostic (6.34e-3)" "unprognostic (1.42e-1)" "unprognostic (5.42e-3)" "unprognostic (1.86e-1)" "unprognostic (2.18e-1)" "unprognostic (1.11e-1)" "unprognostic (1.11e-1)" "unprognostic (2.61e-1)" "unprognostic (2.12e-2)" "unprognostic (1.12e-1)" "potential prognostic unfavorable (5.41e-4)" "unprognostic (1.99e-1)" "unprognostic (9.95e-2)" "unprognostic (2.56e-1)" "unprognostic (1.07e-1)" "unprognostic (2.79e-1)" "unprognostic (2.25e-1)" "unprognostic (4.36e-1)" "unprognostic (1.80e-1)" NPIPB13 ENSG00000198064 "Nuclear pore complex interacting protein family, member B13" A6NJU9 16 30222897-30255268 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 20.7;Epicardial cells: 11.4;Loop of henle epithelial cells: 15.5;Papillary tip epithelial cells: 13.7;Podocytes: 15.2;Proximal tubule cells: 24.0;Renal collecting duct intercalated cells: 17.5;Renal collecting duct principal cells: 13.2;Renal connecting tubule cells: 21.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA053611 Approved Approved Nucleoplasm NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 40: Non-specific - Mixed function" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 56: Non-specific - Sensory perception" "Cluster 105: Non-specific - Mixed function" Nucleoplasm "HPA053611: " "unprognostic (2.42e-2)" "unprognostic (4.26e-1)" "unprognostic (2.49e-2)" "unprognostic (1.69e-1)" "unprognostic (1.50e-1)" "unprognostic (2.30e-1)" "unprognostic (1.08e-2)" "unprognostic (2.63e-2)" "unprognostic (3.60e-1)" "unprognostic (3.29e-1)" "unprognostic (1.15e-1)" "unprognostic (6.71e-2)" "unprognostic (3.84e-2)" "unprognostic (1.01e-1)" "unprognostic (1.43e-1)" "unprognostic (1.51e-2)" "unprognostic (1.67e-1)" "unprognostic (1.16e-2)" "unprognostic (3.21e-1)" "unprognostic (1.72e-1)" "unprognostic (1.20e-1)" "unprognostic (1.64e-1)" "unprognostic (5.33e-1)" "unprognostic (1.67e-1)" "unprognostic (4.20e-2)" NPIPB15 "LOC440348, NPIPL2" ENSG00000196436 "Nuclear pore complex interacting protein family member B15" A6NHN6 16 74376306-74392115 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 45.1" "Group enriched" "Detected in many" 4 "Early spermatids: 238.3;Late primary spermatocytes: 155.6;Late spermatids: 328.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "HPA011188, HPA053611" Supported Approved Nucleoplasm "Intracellular and membrane" "No annotated function" NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 21: Testis - Mixed function" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 70: Intestinal goblet cells - Mucin production" Nucleoplasm "HPA011188: , HPA053611: " "unprognostic (1.42e-1)" "unprognostic (5.56e-2)" "unprognostic (1.94e-1)" "unprognostic (6.97e-2)" "unprognostic (2.17e-1)" "unprognostic (1.33e-1)" "unprognostic (1.09e-1)" "unprognostic (2.98e-1)" "unprognostic (5.74e-2)" "validated prognostic unfavorable (3.19e-4)" "validated prognostic unfavorable (3.65e-5)" "unprognostic (1.18e-1)" "unprognostic (2.79e-2)" "unprognostic (8.90e-2)" "unprognostic (1.81e-2)" "unprognostic (2.90e-1)" "unprognostic (7.43e-2)" "unprognostic (9.89e-2)" "unprognostic (1.82e-1)" "unprognostic (1.91e-3)" "unprognostic (7.94e-2)" "unprognostic (2.30e-1)" "unprognostic (4.15e-1)" "unprognostic (1.48e-1)" "unprognostic (9.14e-2)" "unprognostic (2.78e-1)" "unprognostic (2.61e-2)" "unprognostic (1.27e-1)" "unprognostic (2.61e-1)" NPIPB2 ENSG00000234719 "Nuclear pore complex interacting protein family member B2" A6NJ64 16 11927259-11976643 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 139.0;Plasma cells: 39.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" HPA053611 Supported Approved Nucleoplasm NA NA "Cluster 34: B-cells - Unknown function" "Cluster 40: Non-specific - Mixed function" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 54: Non-specific - Transcription" "Cluster 44: Plasma cells - Antibody production & secretion" Nucleoplasm "HPA053611: " "unprognostic (8.72e-2)" "unprognostic (1.30e-1)" "unprognostic (2.57e-1)" "unprognostic (2.84e-1)" "unprognostic (8.67e-3)" "potential prognostic unfavorable (6.88e-4)" "unprognostic (1.48e-3)" "unprognostic (3.36e-3)" "unprognostic (2.05e-1)" "unprognostic (4.45e-1)" "unprognostic (4.54e-2)" "unprognostic (3.84e-3)" "potential prognostic unfavorable (6.26e-4)" "unprognostic (2.23e-1)" "unprognostic (1.30e-2)" "unprognostic (5.01e-2)" "unprognostic (1.00e-1)" "unprognostic (1.72e-1)" "unprognostic (1.08e-1)" "unprognostic (4.57e-2)" NPIPB3 "KIAA0220, NPIPL3" ENSG00000169246 "Nuclear pore complex interacting protein family member B3" Q92617 16 21402237-21448567 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 4.3;Bergmann glia: 3.8;Brain excitatory neurons: 3.8;Brain inhibitory neurons: 3.4;Choroid plexus epithelial cells: 7.3;Distal convoluted tubule cells: 8.9;Ependymal cells: 3.2;Loop of henle epithelial cells: 5.2;Microglia: 5.2;Oligodendrocyte progenitor cells: 3.5;Oligodendrocytes: 4.5;Papillary tip epithelial cells: 4.7;Podocytes: 4.9;Proximal tubule cells: 11.6;Renal collecting duct intercalated cells: 5.5;Renal collecting duct principal cells: 4.2;Renal connecting tubule cells: 8.5" "Cell type enhanced" "Detected in all" "endothelial cell: 29.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 33.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA053611 Approved Approved Nucleoplasm NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 64: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 56: Non-specific - Sensory perception" "Cluster 102: Non-specific - Mixed function" Nucleoplasm "HPA053611: " "unprognostic (4.52e-2)" "unprognostic (8.26e-3)" "unprognostic (2.06e-2)" "unprognostic (2.92e-2)" "unprognostic (9.22e-2)" "unprognostic (9.24e-2)" "unprognostic (4.10e-1)" "unprognostic (4.71e-2)" "unprognostic (2.11e-1)" "potential prognostic unfavorable (1.20e-6)" "unprognostic (1.04e-1)" "unprognostic (6.90e-2)" "unprognostic (8.89e-2)" "unprognostic (3.49e-2)" "unprognostic (1.23e-1)" "unprognostic (1.32e-1)" "unprognostic (5.00e-2)" "unprognostic (1.28e-1)" "unprognostic (1.12e-1)" "unprognostic (2.94e-2)" "potential prognostic unfavorable (5.81e-4)" "unprognostic (3.07e-3)" "unprognostic (5.16e-2)" "unprognostic (2.94e-2)" "unprognostic (1.20e-1)" "unprognostic (2.97e-1)" "unprognostic (5.32e-2)" "unprognostic (1.87e-3)" "unprognostic (2.32e-2)" NPIPB4 ENSG00000185864 "Nuclear pore complex interacting protein family member B4" C9JG80 16 21834569-21880827 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Early spermatids: 202.3" "Cell type enriched" "Detected in all" 4 "endothelial cell: 121.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" HPA053611 Approved Approved Nucleoplasm NA NA "Cluster 32: Basophils - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 56: Non-specific - Sensory perception" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" Nucleoplasm "HPA053611: " "unprognostic (1.27e-2)" "unprognostic (2.40e-1)" "unprognostic (1.14e-2)" "unprognostic (7.04e-2)" "unprognostic (1.47e-1)" "unprognostic (1.90e-1)" "unprognostic (2.45e-1)" "unprognostic (8.37e-3)" "unprognostic (1.33e-1)" "unprognostic (1.03e-2)" "unprognostic (1.24e-1)" "unprognostic (2.40e-1)" "unprognostic (1.74e-1)" "unprognostic (2.41e-2)" "unprognostic (5.61e-2)" "unprognostic (3.18e-1)" "unprognostic (2.18e-1)" "unprognostic (1.68e-1)" "unprognostic (2.54e-1)" "unprognostic (1.85e-1)" "potential prognostic unfavorable (5.81e-4)" "unprognostic (5.34e-2)" "unprognostic (2.04e-2)" "unprognostic (5.91e-3)" "unprognostic (2.25e-2)" "unprognostic (2.09e-1)" "unprognostic (2.29e-2)" "unprognostic (3.69e-2)" "unprognostic (1.61e-3)" NPIPB5 ENSG00000243716 "Nuclear pore complex interacting protein family member B5" A8MRT5 16 22479121-22536535 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Distal convoluted tubule cells: 71.0;Loop of henle epithelial cells: 54.5;Papillary tip epithelial cells: 50.5;Podocytes: 70.5;Proximal tubule cells: 102.7;Renal collecting duct intercalated cells: 62.7;Renal collecting duct principal cells: 50.3;Renal connecting tubule cells: 82.3" "Cell type enhanced" "Detected in all" "endothelial cell: 31.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA053611 Approved Approved Nucleoplasm NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 56: Non-specific - Sensory perception" "Cluster 105: Non-specific - Mixed function" Nucleoplasm "HPA053611: " "unprognostic (2.31e-2)" "unprognostic (7.73e-2)" "unprognostic (2.17e-2)" "unprognostic (8.43e-3)" "unprognostic (2.09e-1)" "unprognostic (1.48e-1)" "unprognostic (2.26e-1)" "unprognostic (8.43e-3)" "unprognostic (2.05e-1)" "potential prognostic unfavorable (4.93e-4)" "unprognostic (4.15e-2)" "unprognostic (2.79e-1)" "unprognostic (5.72e-2)" "unprognostic (7.56e-2)" "unprognostic (6.56e-2)" "unprognostic (1.82e-1)" "unprognostic (5.01e-3)" "unprognostic (1.25e-1)" "unprognostic (1.25e-1)" "unprognostic (1.30e-1)" "potential prognostic unfavorable (5.58e-4)" "unprognostic (2.26e-2)" "unprognostic (1.56e-1)" "potential prognostic favorable (7.23e-4)" "unprognostic (1.22e-2)" "unprognostic (2.04e-1)" "unprognostic (1.89e-1)" "unprognostic (4.50e-2)" "unprognostic (1.21e-1)" NPIPB6 ENSG00000198156 "Nuclear pore complex interacting protein family member B6" E9PJ23 16 28342517-28363508 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "testis: 36.2" "Group enriched" "Detected in some" 53 "Early spermatids: 287.1;Late primary spermatocytes: 129.5;Late spermatids: 198.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 4.7" "Testis - Early spermatids, Testis - Late spermatids" "HPA011188, HPA053611" Approved Approved Nucleoplasm NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 67: Testis - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" Nucleoplasm "HPA011188: , HPA053611: " "unprognostic (1.19e-1)" "unprognostic (1.66e-1)" "unprognostic (4.72e-2)" "unprognostic (4.30e-2)" "unprognostic (8.23e-3)" "unprognostic (1.85e-2)" "unprognostic (4.81e-2)" "unprognostic (3.70e-1)" "unprognostic (1.98e-1)" "unprognostic (7.97e-2)" NPIPB7 "LOC440350, NPIPL1" ENSG00000233232 "Nuclear pore complex interacting protein family member B7" O75200 16 28456329-28472336 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in many" 5 "testis: 27.2" "Cell type enhanced" "Detected in some" "Early spermatids: 27.8;Late primary spermatocytes: 6.3;Late spermatids: 9.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "HPA011188, HPA053611" Approved Approved Nucleoplasm "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 47: Testis - Mixed function" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 56: Non-specific - Sensory perception" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" Nucleoplasm "HPA011188: , HPA053611: " "unprognostic (1.94e-1)" "unprognostic (2.51e-1)" "potential prognostic unfavorable (1.02e-4)" "unprognostic (2.43e-1)" "unprognostic (7.46e-2)" "unprognostic (2.34e-3)" "unprognostic (1.49e-1)" "unprognostic (2.76e-2)" "unprognostic (3.52e-1)" "unprognostic (1.59e-1)" NPIPB8 ENSG00000255524 "Nuclear pore complex interacting protein family member B8" E9PQR5 16 28637654-28658744 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in many" 8 "testis: 16.9" "Group enriched" "Detected in some" 4 "Early spermatids: 28.1;Late spermatids: 10.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Myeloma: 1.4" "Testis - Early spermatids, Testis - Late spermatids" "HPA011188, HPA053611" Uncertain Approved Nucleoplasm NA NA "Cluster 67: Testis - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" Nucleoplasm "HPA011188: , HPA053611: " "unprognostic (4.30e-2)" "unprognostic (3.77e-3)" NPIPB9 ENSG00000196993 "Nuclear pore complex interacting protein family member B9" 16 28751787-28772864 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 2.6" "Cell type enhanced" "Detected in some" "Early primary spermatocytes: 1.3;Early spermatids: 4.4;Late spermatids: 1.5;Medullary thymic epithelial cells: 2.4;Respiratory ciliated cells: 1.2;Retinal horizontal cells: 2.0;Sertoli cells: 1.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Myeloma: 1.6" "HPA011188, HPA053611" Approved Approved Nucleoplasm NA NA "Cluster 67: Testis - Mixed function" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" Nucleoplasm "HPA011188: , HPA053611: " "unprognostic (3.41e-2)" "unprognostic (7.29e-2)" "unprognostic (1.50e-2)" "unprognostic (1.84e-1)" "unprognostic (3.68e-2)" NPL "C1orf13, DHDPS1, NPL1" ENSG00000135838 "N-acetylneuraminate pyruvate lyase" Q9BXD5 1 182789293-182830384 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 42.4;placenta: 37.9" "Cell type enhanced" "Detected in many" "Astrocytes: 380.2;Cytotrophoblasts: 232.1;Hofbauer cells: 1197.9;Kupffer cells: 465.3;Macrophages: 234.2;Microglia: 336.1;monocytes: 213.9;Neutrophils: 599.3;Proximal tubule cells: 197.3" "Cell type enhanced" "Detected in all" "astrocyte: 523.2;central nervous system macrophage: 434.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 440.3" "Group enriched" "Detected in many" 35 "granulocytes: 440.3;monocytes: 134.3" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Macrophages, Pituitary gland - Macrophages, Spleen - Macrophages, Stomach - Macrophages, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028345, HPA075808" Enhanced Approved "Vesicles,Plasma membrane" NA NA 150000 "Cluster 7: Non-specific - Innate immune response" "Cluster 72: Kidney - Transmembrane transport" "Cluster 38: Sub-cortical - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 2 Vesicles "Plasma membrane" "HPA028345: , HPA075808: " "unprognostic (7.39e-3)" "unprognostic (1.01e-2)" "unprognostic (7.41e-2)" "unprognostic (1.06e-2)" "unprognostic (4.23e-2)" "unprognostic (1.40e-1)" "unprognostic (1.02e-1)" "unprognostic (2.92e-1)" "unprognostic (1.90e-1)" "unprognostic (1.54e-1)" "unprognostic (2.87e-1)" "unprognostic (1.17e-1)" "unprognostic (1.36e-1)" "potential prognostic unfavorable (6.22e-4)" "unprognostic (8.46e-2)" "unprognostic (3.33e-2)" "unprognostic (1.89e-2)" "unprognostic (3.47e-2)" "unprognostic (1.33e-2)" "unprognostic (4.97e-2)" "unprognostic (2.24e-1)" "unprognostic (3.63e-1)" "unprognostic (1.13e-2)" "unprognostic (5.75e-2)" "unprognostic (1.43e-1)" "unprognostic (8.56e-2)" "potential prognostic unfavorable (2.14e-4)" "unprognostic (2.19e-1)" "unprognostic (1.43e-1)" "unprognostic (1.02e-1)" "unprognostic (1.57e-1)" NPLOC4 "FLJ20657, KIAA1499, NPL4" ENSG00000182446 "NPL4 homolog, ubiquitin recognition factor" Q8TAT6 17 81556887-81648465 "Essential proteins, Predicted intracellular proteins, Transporters" "Ubl conjugation pathway" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 155.9" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 20.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021560, HPA023295" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 24: Non-specific - Transcription" "Cluster 18: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 7: Non-specific - Transcription" 47 "Nucleoplasm, Cytosol" "HPA021560: , HPA023295: " "unprognostic (3.61e-1)" "unprognostic (8.63e-2)" "unprognostic (8.67e-3)" "unprognostic (3.65e-3)" "unprognostic (1.27e-1)" "unprognostic (7.73e-2)" "unprognostic (5.31e-2)" "unprognostic (1.41e-1)" "unprognostic (1.59e-1)" "unprognostic (1.77e-3)" "unprognostic (2.10e-2)" "unprognostic (5.62e-2)" "unprognostic (2.33e-2)" "potential prognostic unfavorable (2.92e-8)" "unprognostic (1.32e-2)" "unprognostic (2.15e-2)" "unprognostic (2.16e-2)" "unprognostic (1.17e-2)" "unprognostic (1.71e-2)" "unprognostic (1.93e-1)" "unprognostic (1.71e-2)" "unprognostic (3.50e-2)" "unprognostic (4.33e-3)" "unprognostic (2.26e-1)" "unprognostic (8.46e-2)" "unprognostic (1.59e-3)" "unprognostic (3.33e-1)" "unprognostic (2.79e-1)" "unprognostic (2.73e-1)" "unprognostic (6.70e-2)" "unprognostic (1.45e-2)" NPM1 "B23, NPM" ENSG00000181163 "Nucleophosmin 1" P06748 5 171387116-171411810 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction" "Chaperone, RNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Migrating cytotrophoblasts: 1912.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "HPA011384, CAB012983" Supported Enhanced "Nucleoplasm,Nucleoli rim" NA Yes 2300000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 15: Non-specific - Protein processing" 697 "Nucleoli rim" Nucleoplasm "CAB012983: , HPA011384: " "unprognostic (3.50e-3)" "unprognostic (1.99e-2)" "unprognostic (1.10e-1)" "unprognostic (6.30e-2)" "unprognostic (1.38e-1)" "unprognostic (2.19e-1)" "unprognostic (1.41e-1)" "unprognostic (1.44e-1)" "potential prognostic unfavorable (6.74e-4)" "unprognostic (3.04e-2)" "potential prognostic favorable (1.58e-6)" "unprognostic (3.38e-2)" "unprognostic (1.14e-3)" "validated prognostic unfavorable (2.17e-6)" "validated prognostic unfavorable (3.24e-5)" "potential prognostic unfavorable (7.11e-4)" "unprognostic (5.97e-3)" "unprognostic (1.89e-1)" "unprognostic (3.85e-1)" "unprognostic (4.79e-2)" "unprognostic (7.50e-3)" "potential prognostic unfavorable (1.29e-4)" "unprognostic (6.99e-2)" "unprognostic (4.56e-2)" "unprognostic (5.33e-3)" "unprognostic (3.28e-1)" "unprognostic (4.40e-2)" "unprognostic (3.04e-1)" "unprognostic (4.15e-1)" "unprognostic (5.82e-2)" "unprognostic (5.17e-2)" NPM2 ENSG00000158806 "Nucleophosmin/nucleoplasmin 2" Q86SE8 8 22024125-22036897 "Predicted intracellular proteins" Fertilization "Chaperone, Chromatin regulator, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 62.0;parathyroid gland: 36.9" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 31.2;Brain inhibitory neurons: 28.5;Cone photoreceptor cells: 29.0;Epididymal clear cells: 30.6;Late spermatids: 24.8;Oocytes: 59.9;Other brain neurons: 34.1;Pancreatic islet cells: 25.5;Retinal amacrine cells: 47.5;Retinal ganglion cells: 46.4" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Thyroid Carcinoma (TCGA): 28.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 1.5" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Stomach - Gastric enteroendocrine cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA041070 Enhanced Approved Nucleoplasm,Nucleoli NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 109: Neurons - Neuronal signaling" 9 "Nucleoplasm, Nucleoli" "HPA041070: " "unprognostic (3.05e-2)" "unprognostic (1.53e-1)" "unprognostic (4.61e-2)" "unprognostic (1.59e-2)" "unprognostic (3.54e-2)" "unprognostic (2.37e-1)" "unprognostic (1.82e-2)" "potential prognostic favorable (5.56e-4)" "unprognostic (2.04e-1)" "unprognostic (3.86e-2)" "unprognostic (9.26e-3)" "unprognostic (2.96e-2)" "unprognostic (2.67e-3)" "unprognostic (2.56e-1)" "unprognostic (1.89e-1)" "unprognostic (1.69e-1)" "unprognostic (7.72e-2)" "unprognostic (4.91e-2)" "unprognostic (1.95e-1)" "unprognostic (1.61e-1)" "unprognostic (2.22e-1)" "unprognostic (1.26e-3)" "potential prognostic unfavorable (1.17e-4)" "unprognostic (4.43e-1)" "unprognostic (5.14e-3)" "unprognostic (2.70e-2)" "unprognostic (2.22e-3)" "unprognostic (1.61e-1)" "unprognostic (1.15e-1)" "unprognostic (8.86e-2)" "unprognostic (5.39e-2)" NPM3 ENSG00000107833 "Nucleophosmin/nucleoplasmin 3" O75607 10 101781325-101783446 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 110.9;Decidual stromal cells: 110.6;Differentiating spermatogonia: 106.3;Esophageal basal cells: 228.6;Extravillous trophoblasts: 90.1;Gastric progenitor cells: 91.0;Migrating cytotrophoblasts: 124.0;Oocytes: 115.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036295, HPA036296" Approved Approved "Nucleoli,Actin filaments,Cytosol" NA NA 23000 "Cluster 30: Non-specific - DNA binding" "Cluster 54: Non-specific - Ribosome" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 52: Non-specific - Mitochondria" "Cluster 97: Non-specific - Cellular respiration" 198 "Nucleoli, Actin filaments, Cytosol" "HPA036295: , HPA036296: " "potential prognostic unfavorable (5.15e-4)" "unprognostic (1.80e-2)" "unprognostic (1.55e-2)" "unprognostic (1.04e-1)" "unprognostic (1.96e-2)" "unprognostic (2.67e-1)" "unprognostic (6.38e-2)" "unprognostic (1.66e-2)" "potential prognostic unfavorable (7.86e-4)" "unprognostic (6.55e-2)" "validated prognostic unfavorable (2.02e-6)" "validated prognostic unfavorable (4.27e-4)" "potential prognostic unfavorable (1.41e-4)" "unprognostic (6.09e-3)" "potential prognostic unfavorable (8.50e-5)" "unprognostic (4.17e-3)" "unprognostic (1.18e-2)" "unprognostic (3.05e-2)" "unprognostic (4.30e-1)" "unprognostic (1.40e-1)" "unprognostic (8.82e-3)" "unprognostic (1.43e-2)" "unprognostic (6.55e-2)" "unprognostic (9.91e-3)" "unprognostic (1.81e-1)" "unprognostic (1.84e-1)" "unprognostic (8.97e-2)" "unprognostic (6.27e-2)" "unprognostic (2.15e-1)" "unprognostic (1.52e-2)" "unprognostic (1.05e-1)" NPNT "EGFL6L, POEM" ENSG00000168743 Nephronectin Q6UXI9 4 105894775-106004027 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 185.2;thyroid gland: 224.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 492.7;Alveolar cells type 2: 322.9;Pituicytes/FSCs: 451.8;Podocytes: 1851.9;Renal collecting duct intercalated cells: 199.9;Transitional alveolar cells: 387.6" "Cell type enhanced" "Detected in many" "medium spiny neuron: 98.7;vascular associated smooth muscle cell: 143.6" "Cancer enhanced" "Detected in all" "Thyroid Carcinoma (TCGA): 340.2" "Region enhanced" "Detected in all" "midbrain: 63.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 71.1" "Adipose subcutaneous - Smooth muscle cells, Kidney - Podocytes, Liver - Hepatic stellate cells, Prostate - Smooth muscle cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003711, HPA050203" Supported Approved "Nucleoplasm,Cell Junctions,Cytosol" "Secreted to extracellular matrix" "Developmental protein" NA NA 290000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 57: Podocytes - Glomerular filtration" 2 "Nucleoplasm, Cell Junctions, Cytosol" "HPA003711: , HPA050203: " "unprognostic (1.30e-1)" "unprognostic (3.11e-2)" "unprognostic (3.08e-1)" "unprognostic (4.30e-2)" "unprognostic (1.07e-1)" "unprognostic (7.17e-2)" "unprognostic (1.50e-1)" "unprognostic (1.94e-2)" "unprognostic (1.88e-1)" "unprognostic (1.89e-1)" "potential prognostic favorable (6.46e-7)" "unprognostic (1.31e-3)" "unprognostic (1.07e-1)" "unprognostic (2.04e-1)" "unprognostic (6.37e-2)" "unprognostic (1.39e-1)" "unprognostic (1.83e-2)" "unprognostic (1.00e-3)" "unprognostic (1.97e-2)" "unprognostic (2.49e-2)" "unprognostic (2.03e-1)" "unprognostic (9.55e-2)" "unprognostic (9.21e-2)" "unprognostic (2.74e-1)" "unprognostic (6.76e-2)" "unprognostic (4.03e-2)" "potential prognostic unfavorable (1.25e-5)" "unprognostic (4.88e-2)" "unprognostic (1.38e-1)" "unprognostic (2.17e-2)" "unprognostic (8.71e-2)" NPPA "ANP, PND" ENSG00000175206 "Natriuretic peptide A" P01160 1 11845709-11848345 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hormone, Vasoactive, Vasodilator" "Atrial fibrillation, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 889 "heart muscle: 57628.0" "Cell type enhanced" "Detected in some" "Early spermatids: 5.4;Epicardial cells: 9.1;Epididymal principal cells: 20.8;Platelets: 12.7" "Low cell type specificity" "Detected in some" "Cancer enriched" "Detected in some" 10 "Glioblastoma Multiforme (TCGA): 21.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "lung cancer: 7.5" "Region enriched" "Detected in some" 7 "olfactory bulb: 22.8" "Low region specificity" "Detected in all" "HPA058269, HPA064007" Enhanced "Secreted to blood" Hormone NA NA 1300000 "Cluster 35: Non-specific - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" 12 "HPA058269: , HPA064007: " "unprognostic (7.81e-3)" "unprognostic (4.57e-2)" "unprognostic (1.94e-1)" "potential prognostic favorable (1.99e-5)" "unprognostic (4.77e-2)" "unprognostic (5.04e-3)" "unprognostic (5.60e-2)" NPPB ENSG00000120937 "Natriuretic peptide B" P16860 1 11857464-11858945 "Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Hormone, Vasoactive, Vasodilator" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 535 "heart muscle: 4819.9" "Group enriched" "Detected in some" 7 "Migrating cytotrophoblasts: 72.2;Sertoli cells: 35.4" "Group enriched" "Detected in some" 6 "eccentric medium spiny neuron: 5.8;medium spiny neuron: 1.8" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 3.3" "Region enriched" "Detected in some" 7 "basal ganglia: 6.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 79.4;testis cancer: 62.4" "Region enhanced" "Detected in single" "pons and medulla: 1.4" "Low region specificity" "Detected in all" HPA077324 Approved Vesicles,Cytosol "Secreted to blood" Hormone NA NA 9680 400000 "Cluster 35: Non-specific - Mixed function" "Cluster 33: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 12 Vesicles Cytosol "HPA077324: " "unprognostic (2.00e-3)" "unprognostic (2.10e-2)" "unprognostic (2.00e-2)" NPPC CNP ENSG00000163273 "Natriuretic peptide C" P23582 2 231921809-231926396 "Predicted secreted proteins, Transporters" Osteogenesis "Hormone, Vasoactive" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 7.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 18.1;Basal prostatic cells: 13.8;Brain inhibitory neurons: 39.8;Breast myoepithelial cells: 13.8;Cone photoreceptor cells: 14.5;Epididymal basal cells: 73.2;Epididymal clear cells: 24.5;Esophageal basal cells: 28.5;Müller glia: 20.9;pDCs: 45.1;Pituicytes/FSCs: 16.4;Respiratory basal cells: 16.7" "Cell type enhanced" "Detected in many" "LAMP5-LHX6 and Chandelier: 97.8;midbrain-derived inhibitory: 198.7" "Cancer enhanced" "Detected in many" "Lung Squamous Cell Carcinoma (TCGA): 10.6" "Group enriched" "Detected in all" 5 "medulla oblongata: 75.9;spinal cord: 72.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 9.6" "Adipose subcutaneous - Smooth muscle cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "medulla oblongata: 20.2;spinal cord: 16.4" HPA035362 Uncertain "Secreted to blood" Hormone NA NA 6140 "Cluster 3: Oligodendrocytes - Myelination" "Cluster 43: Hindbrain - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 109: Neurons - Neuronal signaling" 2 "HPA035362: " "unprognostic (3.01e-1)" "unprognostic (4.73e-2)" "unprognostic (7.51e-2)" "unprognostic (1.13e-1)" "unprognostic (3.26e-3)" "unprognostic (2.03e-1)" "unprognostic (7.21e-2)" "potential prognostic favorable (4.39e-5)" "unprognostic (1.41e-2)" "unprognostic (1.69e-1)" "unprognostic (2.16e-1)" "unprognostic (2.06e-1)" "unprognostic (2.35e-3)" NPR1 "ANPa, ANPRA, GUCY2A, NPRA" ENSG00000169418 "Natriuretic peptide receptor 1" P16066 1 153678688-153693992 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "cGMP biosynthesis" "Lyase, Receptor, Vasoactive" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 63.0;blood vessel: 127.4" "Cell type enhanced" "Detected in many" "Adipocytes: 23.4;Alveolar cells type 2: 37.8;Decidual stromal cells: 49.2;Endometrial luminal cells: 29.3;Fallopian secretory cells: 81.0;Fibroblasts: 31.8;Hepatic stellate cells: 32.3;Lymphatic endothelial cells: 28.3;Podocytes: 60.9;Vascular endothelial cells: 57.4" "Group enriched" "Detected in some" 6 "endothelial cell: 14.8;vascular associated smooth muscle cell: 4.1" "Group enriched" "Detected in all" 4 "Kidney Renal Clear Cell Carcinoma (TCGA): 18.0;Kidney Renal Papillary Cell Carcinoma (TCGA): 21.3;Ovary Serous Cystadenocarcinoma (TCGA): 55.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 6.9;ovarian cancer: 7.8;Rhabdoid: 6.5" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Endothelial cells, Breast - Adipocytes (Breast), Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Testis - Endothelial cells" "Region enriched" "Detected in all" 5 "olfactory bulb: 18.7" "Low region specificity" "Detected in many" HPA031087 Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 47: Endothelial cells - Vasculature" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 1 Nucleoli "Nucleoplasm, Plasma membrane" "HPA031087: " "unprognostic (4.79e-1)" "unprognostic (2.46e-1)" "potential prognostic favorable (4.42e-5)" "unprognostic (8.76e-3)" "unprognostic (2.09e-1)" "unprognostic (4.54e-2)" "unprognostic (9.28e-2)" "unprognostic (3.65e-1)" "unprognostic (2.15e-2)" "unprognostic (1.20e-2)" "potential prognostic favorable (2.72e-5)" "unprognostic (9.59e-3)" "potential prognostic favorable (5.21e-5)" "unprognostic (1.42e-2)" "potential prognostic favorable (9.01e-4)" "unprognostic (1.41e-1)" "unprognostic (2.03e-1)" "unprognostic (2.54e-2)" "unprognostic (1.08e-1)" "unprognostic (1.33e-2)" "unprognostic (3.57e-2)" "potential prognostic favorable (8.44e-4)" "unprognostic (1.27e-1)" "unprognostic (6.03e-2)" "unprognostic (3.75e-2)" "unprognostic (2.21e-1)" "unprognostic (2.14e-1)" "potential prognostic unfavorable (7.17e-4)" "unprognostic (1.70e-1)" "unprognostic (9.30e-2)" "potential prognostic unfavorable (6.09e-4)" NPR2 "AMDM, ANPb, ANPRB, GC-B, GUCY2B, NPRB" ENSG00000159899 "Natriuretic peptide receptor 2" P20594 9 35791003-35809732 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "cGMP biosynthesis, Osteogenesis" "Lyase, Receptor" "Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 21.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 24: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 3 "unprognostic (5.75e-3)" "unprognostic (1.84e-1)" "unprognostic (3.01e-1)" "unprognostic (2.17e-1)" "unprognostic (7.64e-3)" "unprognostic (3.65e-2)" "unprognostic (1.49e-1)" "unprognostic (3.14e-1)" "unprognostic (2.15e-1)" "unprognostic (6.62e-3)" "unprognostic (1.44e-3)" "unprognostic (6.32e-2)" "potential prognostic favorable (2.59e-4)" "unprognostic (1.09e-1)" "unprognostic (1.06e-1)" "unprognostic (6.66e-2)" "unprognostic (1.67e-1)" "unprognostic (8.71e-2)" "unprognostic (1.68e-1)" "unprognostic (1.83e-1)" "unprognostic (6.46e-3)" "unprognostic (2.46e-1)" "unprognostic (1.53e-1)" "unprognostic (3.24e-1)" "unprognostic (1.79e-1)" "unprognostic (1.70e-1)" "unprognostic (1.24e-2)" "unprognostic (1.12e-1)" "unprognostic (1.48e-1)" "unprognostic (2.03e-1)" "unprognostic (1.16e-1)" NPR3 "ANPRC, C5orf23, FLJ14054, GUCY2B, NPRC" ENSG00000113389 "Natriuretic peptide receptor 3" P17342 5 32689070-32791724 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 100.5" "Cell type enhanced" "Detected in many" "Adipocytes: 89.0;Cardiomyocytes: 73.6;Hematopoietic stem cells: 222.7;Medullary thymic epithelial cells: 64.8;Megakaryocyte progenitors: 93.0;Megakaryocyte-Erythroid progenitors: 57.0;Podocytes: 290.9;Proximal tubule cells: 138.0;Thymic myoid cells: 51.7" "Cell type enhanced" "Detected in many" "CGE interneuron: 29.3;choroid plexus epithelial cell: 13.1;fibroblast: 12.7" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 60.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "neutrophil: 3.1" "Lineage enriched" "Detected in single" 6 "granulocytes: 3.1" "Cancer enhanced" "Detected in many" "cervical cancer: 20.5" "Pancreas - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA052702 Supported Approved Cytosol NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 72: Kidney - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 88: Proximal tubular cells - Transmembrane transport" 3 Cytosol "HPA052702: " "unprognostic (1.50e-1)" "unprognostic (1.08e-2)" "unprognostic (5.56e-2)" "unprognostic (1.25e-1)" "unprognostic (6.25e-3)" "unprognostic (6.98e-2)" "unprognostic (4.61e-2)" "unprognostic (1.62e-2)" "unprognostic (6.14e-3)" "unprognostic (7.74e-3)" "validated prognostic favorable (3.12e-11)" "validated prognostic favorable (4.10e-5)" "unprognostic (1.10e-2)" "unprognostic (3.95e-3)" "unprognostic (6.74e-3)" "unprognostic (1.80e-1)" "unprognostic (4.33e-1)" "unprognostic (5.22e-2)" "unprognostic (1.91e-2)" "unprognostic (2.83e-1)" "unprognostic (1.11e-1)" "unprognostic (4.57e-2)" "unprognostic (1.34e-1)" "unprognostic (4.40e-3)" "unprognostic (1.34e-1)" "unprognostic (5.15e-2)" "unprognostic (2.94e-2)" "potential prognostic unfavorable (7.25e-4)" "unprognostic (1.71e-1)" "unprognostic (1.10e-2)" "unprognostic (9.23e-2)" NPRL2 "NPR2, NPR2L, TUSC4" ENSG00000114388 "NPR2 like, GATOR1 complex subunit" Q8WTW4 3 50347330-50350826 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "GTPase activation" "Disease variant, Epilepsy, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 90.7;Late primary spermatocytes: 66.0;Late spermatids: 93.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038196, HPA038197" Approved NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 40 "HPA038196: , HPA038197: " "unprognostic (2.45e-2)" "unprognostic (7.64e-2)" "unprognostic (2.75e-1)" "unprognostic (7.76e-3)" "unprognostic (2.24e-1)" "unprognostic (2.44e-2)" "unprognostic (4.11e-1)" "unprognostic (1.26e-1)" "unprognostic (2.18e-1)" "unprognostic (2.96e-3)" "potential prognostic favorable (8.26e-4)" "unprognostic (3.05e-2)" "unprognostic (2.13e-2)" "potential prognostic unfavorable (8.18e-5)" "unprognostic (4.60e-3)" "unprognostic (1.01e-1)" "unprognostic (1.40e-1)" "unprognostic (1.40e-2)" "unprognostic (1.34e-1)" "unprognostic (1.67e-2)" "unprognostic (1.13e-1)" "unprognostic (4.58e-2)" "unprognostic (3.47e-1)" "unprognostic (5.03e-2)" "unprognostic (1.22e-1)" "unprognostic (3.03e-1)" "unprognostic (1.12e-2)" "unprognostic (5.86e-2)" "unprognostic (1.14e-1)" "unprognostic (8.76e-2)" "unprognostic (1.52e-1)" NPRL3 "C16orf35, CGTHBA, HS-40, MARE, NPR3, RMD11" ENSG00000103148 "NPR3 like, GATOR1 complex subunit" Q12980 16 84271-138677 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Retinal ganglion cells: 177.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011741 Uncertain Approved Cytosol NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 41 Cytosol "HPA011741: " "unprognostic (4.50e-2)" "unprognostic (3.33e-3)" "unprognostic (1.72e-1)" "unprognostic (7.57e-2)" "unprognostic (1.76e-1)" "unprognostic (5.30e-2)" "unprognostic (1.78e-1)" "unprognostic (1.19e-1)" "unprognostic (3.69e-1)" "unprognostic (3.12e-1)" "potential prognostic favorable (2.70e-4)" "unprognostic (3.31e-1)" "unprognostic (1.74e-1)" "unprognostic (1.70e-3)" "unprognostic (6.76e-2)" "unprognostic (3.09e-2)" "unprognostic (1.87e-2)" "unprognostic (4.31e-2)" "unprognostic (1.94e-1)" "unprognostic (1.51e-1)" "unprognostic (2.01e-1)" "unprognostic (1.20e-1)" "unprognostic (2.17e-2)" "unprognostic (6.82e-2)" "unprognostic (1.29e-1)" "unprognostic (2.99e-2)" "unprognostic (1.69e-1)" "unprognostic (2.50e-1)" "unprognostic (2.87e-1)" "unprognostic (1.20e-2)" "unprognostic (1.09e-1)" NPS ENSG00000214285 "Neuropeptide S" P0C0P6 10 127549309-127553540 "Predicted secreted proteins" Neuropeptide "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Head and Neck Squamous Cell Carcinoma (TCGA): 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "midbrain: 5.4;pons and medulla: 5.1" "Group enriched" "Detected in some" 9 "cerebral cortex: 2.1;white matter: 1.2" CAB020139 Uncertain "Secreted in brain" Neuropeptide NA NA "Cluster 1: Neuronal - Visual perception" "CAB020139: " NPSR1 "GPR154, GPRA, PGR14" ENSG00000187258 "Neuropeptide S receptor 1" Q6W5P4 7 34658218-34878332 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" Asthma "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 10.6;Brain excitatory neurons: 13.7;Brain inhibitory neurons: 31.7;Early spermatids: 19.6;Foveolar cells: 44.3;Gastric progenitor cells: 16.7;Myonuclei: 13.2;Other brain neurons: 14.1;Syncytiotrophoblasts: 13.3" "Cell type enhanced" "Detected in many" "deep-layer near-projecting: 164.6;mammillary body: 130.5;midbrain-derived inhibitory: 306.9" "Group enriched" "Detected in some" 4 "Colon Adenocarcinoma (TCGA): 5.7;Lung Squamous Cell Carcinoma (TCGA): 2.3;Pancreatic Adenocarcinoma (TCGA): 5.4;Rectum Adenocarcinoma (TCGA): 4.5;Stomach Adenocarcinoma (TCGA): 7.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "Bile duct cancer: 5.5;colorectal cancer: 7.6;Gastric cancer: 9.9;pancreatic cancer: 2.7" "Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 19: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 109: Neurons - Neuronal signaling" 1 "unprognostic (1.05e-1)" "unprognostic (1.89e-2)" "unprognostic (8.16e-2)" "unprognostic (1.84e-1)" "unprognostic (1.41e-2)" "unprognostic (8.43e-2)" "unprognostic (1.82e-1)" "unprognostic (3.94e-1)" "unprognostic (2.02e-1)" "unprognostic (4.93e-2)" NPTN "GP55, GP65, np55, np65, SDFR1, SDR1" ENSG00000156642 Neuroplastin Q9Y639 15 73560014-73634134 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Neurogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 443.1;Neutrophils: 438.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast myoepithelial cells, Colon - Smooth muscle cells, Prostate - Smooth muscle cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051497, HPA072453" Approved Approved "Plasma membrane" NA No 11000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 73: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 11 "Plasma membrane" "HPA051497: , HPA072453: " "unprognostic (1.43e-2)" "unprognostic (4.28e-2)" "unprognostic (7.81e-2)" "unprognostic (1.76e-3)" "unprognostic (2.03e-1)" "unprognostic (1.97e-1)" "unprognostic (1.17e-2)" "unprognostic (1.44e-1)" "unprognostic (2.00e-2)" "unprognostic (2.70e-2)" "potential prognostic favorable (2.87e-7)" "unprognostic (3.13e-3)" "unprognostic (5.14e-2)" "unprognostic (2.09e-1)" "unprognostic (8.72e-2)" "potential prognostic unfavorable (5.88e-5)" "unprognostic (4.12e-2)" "unprognostic (1.91e-1)" "unprognostic (2.98e-1)" "unprognostic (1.06e-1)" "unprognostic (7.47e-2)" "unprognostic (8.56e-2)" "unprognostic (1.59e-1)" "unprognostic (2.60e-1)" "unprognostic (2.26e-1)" "unprognostic (5.02e-2)" "unprognostic (2.86e-1)" "unprognostic (2.03e-1)" "unprognostic (2.45e-1)" "unprognostic (1.55e-1)" "unprognostic (1.89e-1)" NPTX1 ENSG00000171246 "Neuronal pentraxin 1" Q15818 17 80466834-80477843 "Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 188.4" "Group enriched" "Detected in some" 4 "Brain excitatory neurons: 102.3;Cone photoreceptor cells: 107.6;Late spermatids: 103.4;Retinal amacrine cells: 31.7;Somatotrophs: 33.7" "Cell type enhanced" "Detected in all" "deep-layer corticothalamic and 6b: 234.2;deep-layer intratelencephalic: 202.0" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 10.2;Lung Adenocarcinoma (TCGA): 9.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 32.8" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "amygdala: 74.9;cerebellum: 175.3;cerebral cortex: 136.6;hippocampal formation: 175.7" HPA077062 Enhanced Approved Approved "Golgi apparatus,Vesicles" "Secreted in brain" "No annotated function" NA NA 370000 "Cluster 27: Cerebellum - Synaptic function" "Cluster 51: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" 10 "Golgi apparatus" Vesicles "HPA077062: " "unprognostic (2.84e-2)" "unprognostic (5.93e-3)" "potential prognostic unfavorable (4.22e-4)" "unprognostic (2.26e-1)" "unprognostic (5.82e-2)" "unprognostic (2.31e-1)" "unprognostic (1.02e-1)" "unprognostic (2.91e-2)" "unprognostic (2.00e-2)" "unprognostic (1.81e-1)" "unprognostic (3.84e-2)" "potential prognostic unfavorable (8.23e-5)" NPTX2 ENSG00000106236 "Neuronal pentraxin 2" P47972 7 98617285-98629869 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "pituitary gland: 200.0" "Group enriched" "Detected in many" 4 "Corticotrophs: 335.9;Early primary spermatocytes: 165.9;Gonadotrophs: 89.6;Myosatellite cells: 223.7;Pancreatic acinar cells: 118.5;Pancreatic islet cells: 114.5;Peritubular myoid cells: 304.2;Pituicytes/FSCs: 84.4;Schwann cells: 164.3" "Cell type enhanced" "Detected in many" "hippocampal dentate gyrus: 87.2" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 109.3" "Region enhanced" "Detected in all" "cerebral cortex: 280.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 82.5" "Pituitary gland - Corticotropes, Prostate - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB020801, HPA049799, HPA058320" Enhanced Approved "Golgi apparatus,Actin filaments,Centrosome" "Secreted to blood" "No annotated function" NA NA 2490000 220000 "Cluster 20: Pituitary gland - Hormone signaling" "Cluster 29: Forebrain - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 9 "Golgi apparatus, Actin filaments" Centrosome "CAB020801: , HPA049799: , HPA058320: " "unprognostic (7.11e-2)" "unprognostic (6.04e-2)" "unprognostic (4.40e-1)" "unprognostic (3.22e-2)" "unprognostic (2.03e-2)" "unprognostic (3.55e-2)" "unprognostic (2.29e-3)" "unprognostic (2.88e-2)" "unprognostic (1.83e-1)" "unprognostic (2.71e-1)" "potential prognostic unfavorable (1.88e-5)" "unprognostic (3.78e-1)" "potential prognostic unfavorable (1.09e-4)" "unprognostic (1.02e-2)" "unprognostic (5.40e-2)" "unprognostic (3.00e-1)" "unprognostic (1.52e-1)" "potential prognostic unfavorable (1.25e-4)" "unprognostic (5.30e-2)" "unprognostic (1.42e-1)" "unprognostic (4.48e-2)" "unprognostic (8.01e-2)" "unprognostic (4.80e-3)" "unprognostic (2.52e-1)" "unprognostic (3.37e-1)" "unprognostic (5.45e-3)" "unprognostic (1.73e-1)" "unprognostic (5.03e-3)" "unprognostic (2.75e-1)" "unprognostic (1.34e-2)" "unprognostic (8.66e-3)" NPTXR ENSG00000221890 "Neuronal pentraxin receptor" O95502 22 38818452-38844028 "Plasma proteins, Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 179.3" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 100.9;Brain inhibitory neurons: 50.5;Oligodendrocyte progenitor cells: 30.4;Other brain neurons: 40.0;Retinal amacrine cells: 26.4" "Cell type enhanced" "Detected in all" "thalamic excitatory: 307.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 42.6" "Heart muscle - Cardiomyocytes, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001079 Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" Receptor NA NA 260000 "Cluster 73: Brain - Neuronal signaling" "Cluster 29: Forebrain - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" 12 "Plasma membrane, Cytosol" Nucleoplasm "HPA001079: " "potential prognostic favorable (3.95e-5)" "unprognostic (2.38e-2)" "unprognostic (1.76e-1)" "potential prognostic favorable (6.21e-4)" "unprognostic (1.20e-2)" "unprognostic (4.54e-2)" "unprognostic (1.77e-1)" "unprognostic (1.81e-1)" "unprognostic (7.41e-2)" "unprognostic (5.23e-2)" "unprognostic (1.96e-2)" "unprognostic (1.22e-1)" "unprognostic (5.77e-2)" "unprognostic (1.52e-1)" "unprognostic (6.58e-2)" "unprognostic (4.78e-2)" "unprognostic (1.49e-1)" "unprognostic (1.88e-1)" "unprognostic (2.89e-1)" "unprognostic (1.41e-1)" "unprognostic (1.38e-2)" "unprognostic (2.89e-3)" "unprognostic (5.14e-2)" "unprognostic (9.34e-2)" "unprognostic (3.73e-2)" "unprognostic (1.05e-1)" "unprognostic (2.79e-2)" "unprognostic (2.57e-2)" "unprognostic (2.27e-1)" "unprognostic (1.88e-1)" "unprognostic (1.47e-2)" NPVF "C7orf9, RFRP" ENSG00000105954 "Neuropeptide VF precursor" Q9HCQ7 7 25224570-25228486 "Predicted secreted proteins" Neuropeptide "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 41 "retina: 204.2" "Cell type enriched" "Detected in some" 125 "Müller glia: 334.5" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 15 "hypothalamus: 7.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 18 "hypothalamus: 6.1" "Region enriched" "Detected in single" 8 "hypothalamus: 3.9" HPA041733 Enhanced "Secreted in other tissues" Neuropeptide NA NA "Cluster 42: Retina - Visual perception" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 65: Non-specific - Unknown function" "Cluster 11: Muller glia cells - Retinal homeostasis" 2 "HPA041733: " NPW PPL8 ENSG00000183971 "Neuropeptide W" Q8N729 16 2009926-2020755 "Predicted intracellular proteins, Predicted secreted proteins" Neuropeptide "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 25.1" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 62.1;Endometrial stromal cells: 140.4;Epididymal principal cells: 55.7;Foveolar cells: 64.1;Gastric progenitor cells: 66.6;Goblet cells: 38.9;Megakaryocyte progenitors: 38.4;Neuroendocrine cells: 303.1;Undifferentiated spermatogonia: 52.1" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 41.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Bone cancer: 43.9" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA064874 Approved "Secreted to blood" Neuropeptide NA NA 7000000 "Cluster 46: Basophils - Proteolysis" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 40: Non-specific - Unknown function" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" 11 "HPA064874: " "unprognostic (5.85e-2)" "unprognostic (1.11e-1)" "unprognostic (2.48e-3)" "unprognostic (7.60e-2)" "unprognostic (1.26e-1)" "unprognostic (1.33e-1)" "unprognostic (1.81e-1)" "unprognostic (2.58e-1)" "unprognostic (1.61e-1)" "unprognostic (4.12e-2)" "unprognostic (3.74e-2)" "unprognostic (3.19e-1)" "unprognostic (1.38e-2)" "unprognostic (4.28e-2)" "unprognostic (2.94e-3)" "unprognostic (2.59e-1)" "unprognostic (1.97e-1)" "unprognostic (2.46e-1)" "unprognostic (3.08e-1)" "unprognostic (7.07e-3)" "unprognostic (2.34e-1)" "unprognostic (3.55e-1)" "unprognostic (8.13e-2)" NPY PYY4 ENSG00000122585 "Neuropeptide Y" P01303 7 24284188-24291862 "FDA approved drug targets, Plasma proteins, Predicted secreted proteins" Neuropeptide "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 12 "adrenal gland: 115.4;brain: 297.4;prostate: 348.0" "Cell type enriched" "Detected in some" 6 "Prostatic glandular cells: 826.1" "Cell type enriched" "Detected in many" 8 "splatter: 1711.7" "Cancer enriched" "Detected in many" 174 "Prostate Adenocarcinoma (TCGA): 3813.8" "Region enriched" "Detected in many" 9 "hypothalamus: 885.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 15 "Neuroblastoma: 353.3;prostate cancer: 285.9" "Adrenal gland - Adrenal medulla cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB016733, CAB034368, HPA036636, HPA044572, HPA056798" Supported Supported Supported "Golgi apparatus" "Secreted to blood" Neuropeptide NA NA 30700000 18000 "Cluster 78: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 2 "Golgi apparatus" "CAB016733: , CAB034368: , HPA036636: , HPA044572: , HPA056798: " "unprognostic (8.24e-3)" "unprognostic (2.76e-2)" "unprognostic (7.53e-2)" "unprognostic (3.81e-1)" "unprognostic (8.69e-1)" "unprognostic (2.63e-1)" "unprognostic (1.87e-1)" "unprognostic (2.83e-2)" "unprognostic (9.01e-3)" "unprognostic (2.41e-2)" "unprognostic (1.25e-1)" "unprognostic (8.53e-2)" "unprognostic (5.79e-2)" "unprognostic (9.59e-2)" "unprognostic (1.73e-3)" "unprognostic (2.86e-1)" "unprognostic (2.56e-1)" "unprognostic (4.21e-2)" NPY1R NPYR ENSG00000164128 "Neuropeptide Y receptor Y1" P25929 4 163323962-163344832 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 112.7" "Cell type enhanced" "Detected in many" "Adipocytes: 176.0;Brain excitatory neurons: 54.8;Brain inhibitory neurons: 64.4;Breast hormone-responsive cells: 35.1;Distal convoluted tubule cells: 92.2;Hepatic stellate cells: 96.8;Pancreatic duct cells: 75.0;Pericytes: 36.5;Vascular smooth muscle cells: 64.4" "Cell type enhanced" "Detected in many" "hippocampal dentate gyrus: 238.6" "Cancer enriched" "Detected in many" 11 "Breast Invasive Carcinoma (TCGA): 168.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 8 "Bone cancer: 57.1;breast cancer: 33.5" "Adrenal gland - Fibroblasts, Kidney - Fibroblasts, Liver - Sinusoid Endothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Fibroblasts, Skeletal muscle - Smooth muscle cells, Skin - Eccrine sweat gland cells, Spleen - Fibroblasts_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 5: Spleen - Immune response" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 89: Adipocytes - Lipid metabolism" "unprognostic (1.27e-1)" "potential prognostic favorable (3.27e-5)" "unprognostic (5.26e-2)" "unprognostic (3.90e-2)" "unprognostic (1.76e-1)" "unprognostic (9.47e-2)" "unprognostic (1.09e-1)" "unprognostic (8.06e-2)" "unprognostic (2.38e-3)" "unprognostic (2.71e-2)" "unprognostic (2.03e-1)" "unprognostic (4.69e-3)" "potential prognostic favorable (7.23e-6)" "unprognostic (1.24e-1)" "potential prognostic favorable (6.37e-4)" "unprognostic (3.60e-2)" "unprognostic (1.18e-1)" "unprognostic (2.26e-2)" "unprognostic (1.79e-2)" "unprognostic (1.26e-2)" "unprognostic (1.19e-1)" "unprognostic (3.74e-2)" "potential prognostic unfavorable (8.40e-5)" "unprognostic (1.39e-1)" "unprognostic (2.83e-1)" "unprognostic (7.23e-2)" NPY2R ENSG00000185149 "Neuropeptide Y receptor Y2" P49146 4 155208636-155217078 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.8;breast: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Glioblastoma Multiforme (TCGA): 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 14 "Neuroblastoma: 4.5" "Colon - Colon enteroendocrine cells" "Group enriched" "Detected in many" 5 "amygdala: 12.9;basal ganglia: 12.3;hippocampal formation: 46.8;hypothalamus: 23.7" "Region enriched" "Detected in all" 5 "hippocampal formation: 19.3" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 29: Forebrain - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" 1 "unprognostic (1.14e-1)" "unprognostic (4.74e-3)" "unprognostic (4.71e-3)" NPY4R "PP1, PPYR1, Y4" ENSG00000204174 "Neuropeptide Y receptor Y4" P50391 10 46461099-46465958 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "intestine: 5.6;skin 1: 2.8" "Cell type enriched" "Detected in single" 21 "Epicardial cells: 2.3" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Prostate Adenocarcinoma (TCGA): 7.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Bile duct cancer: 10.5" "Adipose visceral - Mesothelial cells, Prostate - Prostate glandular cells" HPA027863 Approved NA NA "Cluster 77: Intestine - Digestion" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 72: Neuronal - Signal transduction" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" "HPA027863: " "unprognostic (4.04e-1)" "unprognostic (8.18e-2)" "unprognostic (5.21e-2)" "unprognostic (1.11e-2)" "unprognostic (6.93e-3)" "unprognostic (2.71e-1)" "unprognostic (2.63e-1)" "unprognostic (5.61e-3)" "unprognostic (1.38e-1)" NPY4R2 CH17-360D5.1 ENSG00000264717 "Neuropeptide Y receptor Y4-2" P0DQD5 10 47918662-47923524 "Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "intestine: 1.6" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Prostate Adenocarcinoma (TCGA): 1.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells" HPA027863 Uncertain NA NA "Cluster 77: Intestine - Digestion" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 72: Neuronal - Signal transduction" "HPA027863: " "unprognostic (2.99e-1)" "unprognostic (7.96e-2)" "unprognostic (5.42e-2)" NPY5R NPYR5 ENSG00000164129 "Neuropeptide Y receptor Y5" Q15761 4 163343892-163351934 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "adipose tissue: 6.7;lymphoid tissue: 8.3" "Cell type enhanced" "Detected in some" "Adipocytes: 16.1;Brain excitatory neurons: 4.1;Brain inhibitory neurons: 7.8;Epicardial cells: 2.3;Fibro-adipogenic progenitors: 2.2;Late primary spermatocytes: 8.2;Other brain neurons: 3.3;Pericytes: 2.8;Vascular smooth muscle cells: 2.7" "Cell type enhanced" "Detected in many" "medium spiny neuron: 15.5" "Cancer enhanced" "Detected in some" "Breast Invasive Carcinoma (TCGA): 3.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Bone cancer: 6.8" "Adrenal gland - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Fibroblasts, Skin - Eccrine sweat gland cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 66: Lymphoid tissue - Immune response" "Cluster 33: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 89: Adipocytes - Lipid metabolism" "potential prognostic favorable (6.40e-6)" "unprognostic (9.74e-2)" "unprognostic (1.75e-1)" "unprognostic (2.36e-1)" NQO1 "DHQU, DIA4, DTD, NMOR1, QR1" ENSG00000181019 "NAD(P)H quinone dehydrogenase 1" P15559 16 69706996-69726668 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 493.1" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 466.0;Esophageal basal cells: 347.8;Esophageal suprabasal cells: 343.2;Foveolar cells: 711.0;Gastric progenitor cells: 880.5;Ocular epithelial cells: 1049.3;Parietal cells: 367.7;Respiratory ciliated cells: 328.2;Salivary duct cells: 558.0;Suprabasal keratinocytes: 255.7" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 38.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Smooth muscle cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007308, CAB012421" Enhanced Enhanced Cytosol NA NA 100000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 100: Stratified epithelial cells - Barrier functions" 12 Cytosol "CAB012421: , HPA007308: " "unprognostic (3.56e-3)" "unprognostic (4.07e-3)" "unprognostic (8.12e-2)" "unprognostic (1.07e-2)" "unprognostic (2.64e-1)" "unprognostic (1.70e-1)" "unprognostic (7.46e-3)" "unprognostic (1.38e-2)" "unprognostic (1.12e-3)" "unprognostic (3.77e-1)" "unprognostic (2.06e-2)" "unprognostic (1.70e-2)" "potential prognostic unfavorable (8.44e-5)" "potential prognostic unfavorable (8.10e-4)" "unprognostic (5.50e-3)" "unprognostic (8.62e-2)" "unprognostic (2.20e-1)" "unprognostic (9.53e-2)" "unprognostic (3.07e-1)" "unprognostic (1.24e-1)" "unprognostic (2.41e-1)" "unprognostic (1.03e-2)" "unprognostic (4.69e-2)" "unprognostic (6.81e-2)" "unprognostic (6.48e-2)" "unprognostic (1.59e-2)" "unprognostic (5.35e-2)" "unprognostic (1.27e-1)" "unprognostic (2.35e-1)" "unprognostic (1.47e-1)" "unprognostic (3.46e-2)" NQO2 "DHQV, DIA6, NMOR2, QR2" ENSG00000124588 "N-ribosyldihydronicotinamide:quinone reductase 2" P16083 6 2987987-3019755 "Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 268.0;Neutrophils: 279.1;Proximal tubule cells: 191.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 241.4" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021283, HPA021332" Enhanced Supported Nucleoplasm,Cytosol NA NA 4600000 "Cluster 28: Neutrophils - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 7: Liver cancer - Metabolism" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 7 Cytosol Nucleoplasm "HPA021283: , HPA021332: " "unprognostic (2.06e-1)" "potential prognostic unfavorable (6.87e-4)" "unprognostic (3.82e-2)" "potential prognostic favorable (4.83e-4)" "unprognostic (2.82e-2)" "unprognostic (4.68e-2)" "unprognostic (1.56e-3)" "unprognostic (8.30e-2)" "unprognostic (3.85e-2)" "potential prognostic unfavorable (9.41e-4)" "unprognostic (1.62e-2)" "unprognostic (1.63e-2)" "potential prognostic favorable (3.59e-4)" "unprognostic (1.02e-2)" "unprognostic (2.35e-2)" "unprognostic (4.54e-1)" "unprognostic (3.05e-1)" "unprognostic (1.06e-1)" "unprognostic (1.86e-1)" "unprognostic (1.63e-2)" "unprognostic (1.57e-1)" "unprognostic (8.19e-2)" "unprognostic (7.02e-3)" "unprognostic (1.99e-1)" "unprognostic (2.60e-1)" "unprognostic (1.01e-1)" "unprognostic (1.40e-1)" "unprognostic (2.54e-1)" "unprognostic (1.48e-1)" "unprognostic (2.00e-1)" "unprognostic (2.14e-1)" NR0B1 "AHC, AHCH, DAX1, DSS" ENSG00000169297 "Nuclear receptor subfamily 0 group B member 1" P51843 X 30304206-30309390 "Cancer-related genes, Disease related genes, Human disease related genes, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Receptor, Repressor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "adrenal gland: 34.7;testis: 19.7" "Cell type enhanced" "Detected in some" "Adrenal cortex cells: 58.8;Adrenal medulla cells: 10.6;Corticotrophs: 6.8;Epididymal efferent duct ciliated cells: 12.2;Gonadotrophs: 21.7;Oligodendrocyte progenitor cells: 18.8;Pancreatic islet cells: 20.7;Sertoli cells: 47.5" "Group enriched" "Detected in some" 35 "committed oligodendrocyte precursor: 7.2;oligodendrocyte precursor cell: 21.5" "Cancer enhanced" "Detected in many" "Lung Squamous Cell Carcinoma (TCGA): 11.6" "Region enriched" "Detected in many" 7 "hypothalamus: 10.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 57.1" "Adrenal gland - Adrenal cortex cells, Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Sertoli cells" "Not detected" "Not detected" "Region enhanced" "Detected in single" "basal ganglia: 1.0" "HPA061948, HPA067207" Supported "Nuclear speckles,Vesicles,Centriolar satellite" NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 7: Liver cancer - Metabolism" "Cluster 18: Adrenal cortex cells - Steroidogensis" 20 "Nuclear speckles" "Vesicles, Centriolar satellite" "HPA061948: , HPA067207: " "unprognostic (3.24e-1)" "unprognostic (1.12e-1)" "unprognostic (4.65e-2)" "potential prognostic favorable (1.25e-4)" "unprognostic (3.32e-2)" "unprognostic (4.96e-2)" "unprognostic (1.51e-2)" "unprognostic (2.59e-1)" "unprognostic (6.16e-2)" "unprognostic (1.07e-1)" "unprognostic (8.96e-3)" "unprognostic (5.37e-2)" "unprognostic (1.91e-3)" NR0B2 SHP ENSG00000131910 "Nuclear receptor subfamily 0 group B member 2" Q15466 1 26911489-26913975 "Disease related genes, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Receptor, Repressor" "Disease variant, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 72.2;liver: 140.3" "Cell type enhanced" "Detected in some" "Cholangiocytes: 104.9;Enterocytes: 50.0;Foveolar cells: 33.8;Gastric chief cells: 28.4;Hepatocytes: 164.4;Neuroendocrine cells: 23.0;Pancreatic acinar cells: 58.0;Pancreatic duct cells: 86.0;Paneth cells: 23.2;Parietal cells: 63.6" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Kidney Chromophobe (TCGA): 73.4;Liver Hepatocellular Carcinoma (TCGA): 68.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 11.0;liver cancer: 16.0" "Heart muscle - Cardiomyocytes, Kidney - Intercalated cells, Lung - Alveolar cells type 2" "Region enriched" "Detected in single" 6 "cerebellum: 1.7" "Not detected" "Not detected" HPA003983 Supported Nucleoplasm,Vesicles NA NA "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 93: Hepatocytes - Bile production & excretion" 40 Nucleoplasm Vesicles "HPA003983: " "unprognostic (3.06e-2)" "unprognostic (1.25e-1)" "unprognostic (5.09e-2)" "unprognostic (4.73e-1)" "unprognostic (8.85e-2)" "unprognostic (3.56e-2)" "potential prognostic favorable (2.48e-4)" "potential prognostic favorable (8.20e-5)" "unprognostic (2.84e-2)" "unprognostic (2.14e-3)" "unprognostic (2.49e-1)" "unprognostic (2.00e-2)" "unprognostic (7.34e-2)" "unprognostic (1.77e-1)" "unprognostic (1.65e-1)" "unprognostic (4.46e-1)" NR1D1 "ear-1, hRev, Rev-ErbAalpha, REVERBA, REVERBalpha, THRA1, THRAL" ENSG00000126368 "Nuclear receptor subfamily 1 group D member 1" P20393 17 40092793-40100589 "Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 329.3" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 102.4;Epididymal efferent duct absorptive cells: 146.4;Esophageal apical cells: 146.7;Ocular epithelial cells: 169.0;Oocytes: 110.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 18.5" "Group enriched" "Detected in many" 6 "monocytes: 5.6;T-cells: 18.5" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007935 Uncertain Supported "Nuclear bodies" NA Yes "Cluster 1: T-cells - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 17 "Nuclear bodies" "HPA007935: " "unprognostic (8.14e-2)" "unprognostic (4.08e-3)" "unprognostic (6.78e-2)" "unprognostic (4.45e-2)" "unprognostic (7.13e-2)" "unprognostic (5.22e-1)" "unprognostic (2.69e-2)" "unprognostic (2.80e-2)" "unprognostic (4.15e-2)" "unprognostic (2.67e-1)" "unprognostic (2.65e-2)" "potential prognostic favorable (1.78e-4)" "unprognostic (7.14e-3)" "unprognostic (2.34e-2)" "unprognostic (3.57e-1)" "unprognostic (6.07e-2)" "unprognostic (2.24e-3)" "unprognostic (1.73e-1)" "unprognostic (1.14e-1)" "unprognostic (1.72e-3)" "unprognostic (1.62e-1)" "unprognostic (1.20e-2)" "unprognostic (2.31e-2)" "unprognostic (2.28e-1)" "unprognostic (1.61e-1)" "unprognostic (9.12e-2)" "unprognostic (2.82e-3)" "unprognostic (2.28e-3)" "unprognostic (2.75e-1)" "unprognostic (2.92e-1)" "unprognostic (9.59e-3)" NR1D2 "BD73, EAR-1r, Hs.37288, HZF2, REVERBB, REVERBbeta, RVR" ENSG00000174738 "Nuclear receptor subfamily 1 group D member 2" Q14995 3 23945286-23980617 "Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 383.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053868, HPA054798" Approved Supported Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 51: Secretory epithelial cells - Mixed function" 16 Nucleoplasm "HPA053868: , HPA054798: " "unprognostic (3.36e-2)" "unprognostic (5.80e-2)" "unprognostic (9.95e-2)" "unprognostic (1.54e-2)" "unprognostic (4.31e-2)" "unprognostic (2.32e-1)" "unprognostic (1.06e-1)" "unprognostic (2.33e-1)" "unprognostic (6.41e-2)" "unprognostic (4.46e-2)" "potential prognostic favorable (1.26e-4)" "unprognostic (4.65e-2)" "unprognostic (2.97e-2)" "unprognostic (1.26e-1)" "unprognostic (1.50e-1)" "unprognostic (2.33e-1)" "unprognostic (3.78e-1)" "unprognostic (1.21e-1)" "unprognostic (9.52e-2)" "unprognostic (3.80e-2)" "unprognostic (1.14e-3)" "unprognostic (2.55e-1)" "unprognostic (3.39e-1)" "unprognostic (4.99e-2)" "unprognostic (1.44e-3)" "unprognostic (1.36e-1)" "unprognostic (4.71e-1)" "potential prognostic unfavorable (5.46e-4)" "unprognostic (1.02e-1)" "unprognostic (3.87e-2)" "unprognostic (5.26e-2)" NR1H2 "LXR-b, LXRb, NER, NER-I, RIP15, UNR" ENSG00000131408 "Nuclear receptor subfamily 1 group H member 2" P55055 19 50329653-50383388 "Cancer-related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 191.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005446, HPA056838, HPA070212" Uncertain Enhanced Nucleoplasm,Vesicles NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 18: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 21 Nucleoplasm Vesicles "HPA005446: , HPA056838: , HPA070212: " "unprognostic (8.48e-3)" "unprognostic (5.17e-2)" "unprognostic (1.45e-1)" "unprognostic (2.29e-1)" "unprognostic (1.27e-1)" "unprognostic (2.60e-1)" "unprognostic (1.35e-1)" "unprognostic (9.54e-2)" "unprognostic (4.70e-2)" "unprognostic (4.32e-2)" "unprognostic (1.05e-2)" "unprognostic (1.07e-1)" "unprognostic (5.55e-2)" "unprognostic (9.57e-3)" "unprognostic (3.47e-2)" "unprognostic (1.04e-1)" "unprognostic (9.08e-2)" "unprognostic (5.66e-2)" "unprognostic (9.89e-2)" "unprognostic (2.50e-2)" "unprognostic (1.19e-1)" "unprognostic (3.16e-1)" "unprognostic (1.46e-2)" "unprognostic (5.84e-2)" "unprognostic (5.68e-2)" "unprognostic (6.75e-2)" "unprognostic (2.16e-1)" "unprognostic (7.72e-2)" "unprognostic (8.52e-2)" "unprognostic (8.50e-2)" "unprognostic (2.97e-1)" NR1H3 "LXR-a, LXRa, RLD-1" ENSG00000025434 "Nuclear receptor subfamily 1 group H member 3" Q13133 11 47248300-47269033 "Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors, Transporters" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 84.3" "Cell type enhanced" "Detected in many" "Enterocytes: 68.6;Hepatocytes: 72.0;Kupffer cells: 226.5;Late spermatids: 72.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 13.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036443, CAB037109" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 28: Liver & Adrenal gland - Secretion" "Cluster 19: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 29 Nucleoplasm Cytosol "CAB037109: , HPA036443: " "unprognostic (7.63e-2)" "unprognostic (5.75e-3)" "unprognostic (2.25e-3)" "unprognostic (4.95e-2)" "unprognostic (1.45e-1)" "unprognostic (2.70e-1)" "unprognostic (2.10e-2)" "unprognostic (7.57e-2)" "unprognostic (6.60e-3)" "unprognostic (1.36e-2)" "unprognostic (5.62e-3)" "unprognostic (2.15e-2)" "unprognostic (7.93e-2)" "unprognostic (2.13e-3)" "unprognostic (6.59e-2)" "unprognostic (1.45e-2)" "unprognostic (1.29e-2)" "unprognostic (1.13e-1)" "unprognostic (1.24e-1)" "unprognostic (2.42e-1)" "unprognostic (9.60e-2)" "unprognostic (9.36e-2)" "unprognostic (2.91e-1)" "unprognostic (1.34e-1)" "unprognostic (5.76e-2)" "unprognostic (1.00e-1)" "unprognostic (2.40e-1)" "unprognostic (1.47e-1)" "unprognostic (3.78e-2)" "unprognostic (1.88e-1)" "unprognostic (2.18e-2)" NR1H4 "FXR, HRR-1, HRR1, RIP14" ENSG00000012504 "Nuclear receptor subfamily 1 group H member 4" Q96RI1 12 100473708-100564414 "Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors, Transporters" "Immunity, Inflammatory response, Innate immunity, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor, Repressor" "Disease variant, FDA approved drug targets, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 36.8;liver: 112.7" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 212.1;Cholangiocytes: 212.2;Enteric transient amplifying cells: 137.8;Enterocytes: 673.5;Hepatic stellate cells: 154.9;Hepatocytes: 255.6;Loop of henle epithelial cells: 82.8;Oocytes: 138.2;Paneth cells: 77.3;Proximal tubule cells: 174.9;Renal collecting duct principal cells: 82.3;Urothelial cells: 87.0" "Group enriched" "Detected in some" 5 "ependymal cell: 24.3;vascular associated smooth muscle cell: 13.6" "Group enriched" "Detected in many" 10 "Kidney Renal Clear Cell Carcinoma (TCGA): 37.4;Kidney Renal Papillary Cell Carcinoma (TCGA): 37.4;Liver Hepatocellular Carcinoma (TCGA): 40.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Gastric cancer: 3.8;Kidney cancer: 14.8;liver cancer: 12.1" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Prostate - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA047699 Supported "Nucleoplasm,Nuclear speckles,Primary cilium tip,Cytosol" NA NA "Cluster 76: Non-specific - Metabolism" "Cluster 48: Non-specific - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 1: Enterocytes - Absorption and Digestion" 13 "Nucleoplasm, Nuclear speckles" "Primary cilium tip, Cytosol" "HPA047699: " "unprognostic (3.35e-1)" "unprognostic (7.52e-2)" "unprognostic (4.48e-2)" "unprognostic (2.87e-1)" "potential prognostic favorable (7.74e-4)" "unprognostic (1.94e-2)" "unprognostic (1.55e-1)" "unprognostic (1.59e-1)" "unprognostic (7.80e-2)" "unprognostic (7.18e-2)" "unprognostic (2.10e-2)" "unprognostic (3.86e-3)" "unprognostic (3.52e-1)" "unprognostic (1.55e-1)" NR1I2 "BXR, ONR1, PAR2, PXR, SXR" ENSG00000144852 "Nuclear receptor subfamily 1 group I member 2" O75469 3 119780484-119818487 "FDA approved drug targets, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors, Transporters" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "intestine: 29.4;liver: 44.3" "Cell type enhanced" "Detected in some" "Colonocytes: 26.8;Enteric stem cells: 13.6;Enteric transient amplifying cells: 16.1;Enterocytes: 61.1;Gastric progenitor cells: 7.7;Goblet cells: 9.4;Hepatocytes: 39.7;Paneth cells: 11.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 26 "Colon Adenocarcinoma (TCGA): 17.7;Liver Hepatocellular Carcinoma (TCGA): 10.5;Pancreatic Adenocarcinoma (TCGA): 5.1;Rectum Adenocarcinoma (TCGA): 19.0;Stomach Adenocarcinoma (TCGA): 5.4" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 15 "NK-cell: 2.9" "Lineage enriched" "Detected in single" 15 "NK-cells: 2.9" "Cancer enhanced" "Detected in some" "colorectal cancer: 5.3;Gastric cancer: 3.9" "Colon - Colon enterocytes, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Skin - Hair cortex cells, Skin - Inner root sheath cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA029309, HPA055121, HPA073926" Supported Nucleoplasm NA NA "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 21 Nucleoplasm "HPA029309: , HPA055121: , HPA073926: " "unprognostic (1.51e-1)" "unprognostic (3.36e-2)" "unprognostic (1.47e-2)" "unprognostic (6.31e-3)" "potential prognostic favorable (4.75e-6)" "unprognostic (3.51e-2)" "unprognostic (7.04e-2)" "unprognostic (2.29e-3)" "unprognostic (1.33e-1)" "unprognostic (2.38e-1)" NR1I3 "CAR, CAR1, MB67" ENSG00000143257 "Nuclear receptor subfamily 1 group I member 3" Q14994 1 161229666-161238244 "Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "liver: 158.8" "Cell type enriched" "Detected in some" 7 "Hepatocytes: 194.8" "Group enriched" "Detected in some" 5 "eccentric medium spiny neuron: 2.5;medium spiny neuron: 7.0" "Cancer enriched" "Detected in some" 13 "Liver Hepatocellular Carcinoma (TCGA): 54.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA051365 Supported Nucleoplasm NA NA "Cluster 53: Liver - Plasma proteins" "Cluster 34: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 93: Hepatocytes - Bile production & excretion" 10 Nucleoplasm "HPA051365: " "unprognostic (2.35e-2)" "unprognostic (2.89e-2)" "potential prognostic favorable (2.00e-4)" "unprognostic (1.05e-2)" "unprognostic (6.60e-3)" "unprognostic (7.58e-3)" "unprognostic (1.37e-1)" NR2C1 "TR2, TR2-11" ENSG00000120798 "Nuclear receptor subfamily 2 group C member 1" P13056 12 95020229-95073628 "Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 172.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035040, HPA035041, HPA067767" Supported Supported "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 67: Testis - Mixed function" "Cluster 2: Neurons - Nucleosome" "Cluster 3: Rhabdoid - Membrane components" "Cluster 94: Gonadal somatic cells - Mixed function" 21 Nucleoplasm "Cell Junctions, Cytosol" "HPA035040: , HPA035041: , HPA067767: " "unprognostic (8.52e-2)" "unprognostic (9.65e-2)" "unprognostic (2.53e-1)" "unprognostic (1.93e-1)" "unprognostic (2.03e-2)" "unprognostic (3.71e-2)" "unprognostic (1.04e-1)" "unprognostic (6.85e-3)" "unprognostic (3.53e-1)" "potential prognostic unfavorable (2.36e-4)" "unprognostic (2.70e-3)" "unprognostic (7.68e-2)" "unprognostic (4.55e-2)" "unprognostic (2.18e-3)" "unprognostic (2.64e-1)" "unprognostic (1.69e-1)" "unprognostic (9.66e-2)" "unprognostic (7.65e-2)" "unprognostic (1.66e-2)" "unprognostic (7.29e-2)" "unprognostic (2.11e-1)" "unprognostic (1.16e-1)" "unprognostic (5.13e-2)" "unprognostic (2.57e-1)" "unprognostic (4.71e-2)" "unprognostic (2.65e-2)" "unprognostic (1.37e-2)" "unprognostic (1.64e-2)" "unprognostic (1.44e-1)" "unprognostic (1.01e-1)" "unprognostic (7.20e-2)" NR2C2 "hTAK1, TAK1, TR2R1, TR4" ENSG00000177463 "Nuclear receptor subfamily 2 group C member 2" P49116 3 14947583-15053600 "Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 655.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Pancreas - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006313 Approved Enhanced Nucleoplasm NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 24: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 39 Nucleoplasm "HPA006313: " "unprognostic (4.20e-3)" "unprognostic (8.78e-2)" "unprognostic (7.17e-2)" "unprognostic (3.44e-3)" "unprognostic (9.54e-2)" "unprognostic (2.59e-2)" "unprognostic (1.26e-1)" "unprognostic (5.96e-3)" "potential prognostic favorable (9.69e-5)" "unprognostic (1.72e-3)" "unprognostic (3.22e-3)" "unprognostic (3.92e-3)" "unprognostic (1.30e-1)" "unprognostic (7.85e-3)" "unprognostic (3.59e-1)" "unprognostic (1.39e-1)" "unprognostic (6.52e-2)" "unprognostic (4.11e-2)" "unprognostic (1.11e-1)" "unprognostic (7.11e-2)" "unprognostic (1.14e-1)" "unprognostic (4.71e-2)" "unprognostic (6.89e-2)" "unprognostic (2.92e-2)" "unprognostic (1.77e-3)" "unprognostic (8.12e-3)" "unprognostic (1.37e-1)" "unprognostic (6.30e-2)" "unprognostic (2.05e-1)" "unprognostic (1.37e-2)" "unprognostic (2.99e-3)" NR2C2AP TRA16 ENSG00000184162 "Nuclear receptor 2C2 associated protein" Q86WQ0 19 19201409-19203414 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal basal cells: 46.7;Esophageal basal cells: 58.2;Migrating cytotrophoblasts: 47.5;Oocytes: 46.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042054, HPA055653" Approved Supported Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 54: Non-specific - Ribosome" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 10 Nucleoplasm "HPA042054: , HPA055653: " "unprognostic (2.75e-1)" "unprognostic (1.85e-2)" "unprognostic (2.18e-1)" "unprognostic (3.22e-2)" "unprognostic (6.85e-3)" "unprognostic (9.00e-2)" "unprognostic (5.58e-2)" "unprognostic (1.39e-1)" "potential prognostic favorable (9.07e-4)" "unprognostic (1.71e-2)" "unprognostic (3.67e-2)" "unprognostic (4.05e-2)" "unprognostic (1.88e-1)" "potential prognostic unfavorable (1.12e-4)" "unprognostic (1.92e-3)" "unprognostic (1.88e-1)" "unprognostic (1.64e-3)" "unprognostic (1.16e-2)" "unprognostic (5.50e-3)" "unprognostic (7.78e-2)" "unprognostic (1.44e-1)" "unprognostic (1.46e-3)" "unprognostic (7.36e-2)" "unprognostic (3.23e-2)" "unprognostic (6.70e-2)" "unprognostic (3.32e-3)" "unprognostic (1.83e-2)" "unprognostic (5.09e-3)" "unprognostic (9.56e-3)" "unprognostic (3.48e-2)" "unprognostic (1.22e-1)" NR2E1 "TLL, TLX, XTLL" ENSG00000112333 "Nuclear receptor subfamily 2 group E member 1" Q9Y466 6 108166022-108188805 "Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Receptor, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 56 "brain: 23.9;choroid plexus: 7.8;retina: 28.4" "Cell type enriched" "Detected in some" 4 "Müller glia: 91.3" "Group enriched" "Detected in some" 4 "astrocyte: 15.9;CGE interneuron: 26.1;choroid plexus epithelial cell: 7.4" "Cancer enriched" "Detected in some" 9 "Glioblastoma Multiforme (TCGA): 12.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 2.5" "Spleen - Neutrophils_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA036954, HPA055642" Uncertain Approved "Nuclear bodies" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 72: Neuronal - Signal transduction" "Cluster 11: Muller glia cells - Retinal homeostasis" 8 "Nuclear bodies" "HPA036954: , HPA055642: " "unprognostic (1.25e-1)" "potential prognostic unfavorable (9.28e-6)" "unprognostic (7.83e-2)" "unprognostic (3.06e-1)" NR2E3 "PNR, rd7, RP37" ENSG00000278570 "Nuclear receptor subfamily 2 group E member 3" Q9Y5X4 15 71792638-71818259 "Disease related genes, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Sensory transduction, Transcription, Transcription regulation, Vision" "DNA-binding, Receptor, Repressor" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 125 "retina: 121.9" "Cell type enriched" "Detected in many" 42 "Rod photoreceptor cells: 861.9" "Cell type enhanced" "Detected in some" "endothelial cell: 6.8;fibroblast: 4.1" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate basal glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 42: Retina - Visual perception" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 1: Neuronal - Visual perception" "Cluster 79: Photoreceptor cells - Phototransduction" 2 "unprognostic (7.13e-2)" "unprognostic (3.87e-1)" NR2F1 "COUP-TFI, COUPTF1, EAR-3, ERBAL3, SVP44, TCFCOUP1, TFCOUP1" ENSG00000175745 "Nuclear receptor subfamily 2 group F member 1" P10589 5 93583222-93594611 "Disease related genes, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor, Repressor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 157.9;Bergmann glia: 279.9;Endometrial stromal cells: 289.6;Ependymal cells: 144.3;Fibroblasts: 192.4;Hepatic stellate cells: 238.8;Leydig cells: 134.0;Lymphatic endothelial cells: 350.1;Mesothelial cells: 204.2;Pericytes: 132.3;Schwann cells: 110.1;Smooth muscle cells: 109.4" "Cell type enhanced" "Detected in many" "fibroblast: 801.9;pericyte: 405.7" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 57.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Rhabdoid: 121.0" "Adipose visceral - Mesothelial cells, Adrenal gland - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblasts_1, Pituitary gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019281, HPA058974" Approved Nucleoplasm,Cytosol NA NA "Cluster 75: Ovary - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 5: Rhabdoid - Unknown function" "Cluster 108: Fibroblasts - ECM organization" 19 Nucleoplasm Cytosol "CAB019281: , HPA058974: " "unprognostic (2.63e-3)" "unprognostic (8.04e-2)" "unprognostic (6.73e-2)" "unprognostic (4.15e-2)" "unprognostic (8.89e-2)" "unprognostic (1.55e-2)" "unprognostic (4.99e-1)" "unprognostic (3.74e-1)" "unprognostic (5.16e-2)" "unprognostic (5.52e-2)" "potential prognostic favorable (5.16e-5)" "unprognostic (1.05e-3)" "unprognostic (1.03e-3)" "unprognostic (6.09e-3)" "unprognostic (9.71e-2)" "unprognostic (2.59e-2)" "unprognostic (7.98e-2)" "unprognostic (2.96e-1)" "unprognostic (2.18e-1)" "unprognostic (9.08e-3)" "unprognostic (5.63e-2)" "unprognostic (1.94e-2)" "unprognostic (2.36e-2)" "unprognostic (5.33e-2)" "unprognostic (3.48e-1)" "unprognostic (1.38e-1)" "unprognostic (6.70e-2)" "unprognostic (2.00e-2)" "unprognostic (4.05e-1)" "unprognostic (9.67e-2)" "unprognostic (6.65e-3)" NR2F2 "ARP1, COUP-TFII, COUPTF2, COUPTFB, NF-E3, SVP40, TFCOUP2" ENSG00000185551 "Nuclear receptor subfamily 2 group F member 2" P24468 15 96325938-96340263 "Disease related genes, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 470.5;Gastric chief cells: 412.8;Leydig cells: 526.7;Lymphatic endothelial cells: 527.8;Ovarian stromal cells: 313.7;Parietal cells: 390.7;Pericytes: 683.4;Peritubular myoid cells: 687.8;Vascular smooth muscle cells: 457.5" "Group enriched" "Detected in many" 4 "fibroblast: 309.0;midbrain-derived inhibitory: 334.6;pericyte: 559.7;vascular associated smooth muscle cell: 426.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblasts_1, Minor Salivary Gland - Endothelial cells, Pituitary gland - Fibroblasts, Skin - Endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058974 Approved Nucleoplasm,Cytosol NA NA "Cluster 75: Ovary - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 110: Mural cells - ECM organization" 14 Nucleoplasm Cytosol "HPA058974: " "potential prognostic favorable (5.41e-5)" "unprognostic (2.00e-1)" "unprognostic (6.98e-2)" "unprognostic (3.16e-3)" "unprognostic (1.75e-2)" "unprognostic (2.63e-3)" "unprognostic (2.68e-1)" "unprognostic (1.28e-3)" "unprognostic (5.01e-2)" "unprognostic (1.54e-1)" "potential prognostic favorable (4.59e-4)" "unprognostic (2.33e-3)" "unprognostic (1.68e-1)" "unprognostic (1.51e-1)" "unprognostic (1.14e-2)" "unprognostic (2.88e-2)" "unprognostic (2.38e-2)" "unprognostic (2.37e-1)" "unprognostic (5.81e-2)" "unprognostic (1.02e-1)" "unprognostic (2.78e-1)" "unprognostic (5.68e-2)" "unprognostic (8.63e-2)" "unprognostic (1.21e-1)" "unprognostic (3.60e-3)" "potential prognostic favorable (9.60e-4)" "unprognostic (7.53e-2)" "unprognostic (4.11e-3)" "unprognostic (2.17e-2)" "unprognostic (7.77e-2)" "unprognostic (1.02e-1)" NR2F6 "EAR-2, EAR2, ERBAL2" ENSG00000160113 "Nuclear receptor subfamily 2 group F member 6" P10588 19 17231883-17245919 "Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 104.3" "Cell type enhanced" "Detected in many" "Colonocytes: 154.4;Esophageal apical cells: 146.8;Hepatocytes: 176.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB079917 Supported "Nuclear speckles,Cytosol" NA Yes "Cluster 3: Non-specific - Nuclear processes" "Cluster 70: Non-specific - Protein processing" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 23: Non-specific - Transcription" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 14 "Nuclear speckles" Cytosol "CAB079917: " "unprognostic (1.78e-1)" "unprognostic (3.34e-1)" "unprognostic (3.30e-1)" "unprognostic (1.19e-2)" "unprognostic (1.67e-1)" "unprognostic (2.04e-2)" "unprognostic (2.89e-1)" "unprognostic (2.06e-1)" "unprognostic (3.41e-2)" "unprognostic (7.17e-2)" "unprognostic (1.67e-1)" "unprognostic (4.23e-2)" "unprognostic (2.81e-1)" "unprognostic (2.02e-1)" "unprognostic (1.01e-2)" "unprognostic (1.55e-2)" "unprognostic (1.46e-1)" "unprognostic (1.78e-1)" "unprognostic (1.42e-1)" "unprognostic (1.40e-1)" "unprognostic (2.48e-1)" "unprognostic (1.92e-1)" "unprognostic (1.04e-1)" "unprognostic (6.08e-2)" "unprognostic (1.80e-1)" "unprognostic (6.67e-2)" "unprognostic (6.15e-2)" "unprognostic (2.38e-1)" "unprognostic (5.06e-2)" "unprognostic (4.05e-2)" "unprognostic (1.77e-1)" NR3C1 "GR, GRL" ENSG00000113580 "Nuclear receptor subfamily 3 group C member 1" P04150 5 143277931-143435512 "Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Apoptosis, Cell cycle, Cell division, Chromosome partition, Mitosis, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Receptor, RNA-binding" "Disease variant, FDA approved drug targets, Pseudohermaphroditism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Corticotrophs: 1168.5;Myonuclei: 691.5;Neutrophils: 1012.2;pDCs: 861.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Testis - Peritubular cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004248, CAB010435" Supported Supported Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 9: T-cells - Adaptive immunity: Regulation" 122 "Nucleoplasm, Cytosol" Mitochondria "CAB010435: , HPA004248: " "unprognostic (9.89e-2)" "unprognostic (2.02e-1)" "unprognostic (1.77e-2)" "unprognostic (1.21e-1)" "unprognostic (9.03e-2)" "unprognostic (3.09e-1)" "unprognostic (6.11e-2)" "unprognostic (1.73e-1)" "unprognostic (1.37e-1)" "potential prognostic unfavorable (1.01e-5)" "potential prognostic favorable (9.64e-5)" "unprognostic (2.33e-2)" "unprognostic (8.90e-2)" "unprognostic (1.35e-1)" "unprognostic (1.06e-3)" "unprognostic (2.63e-1)" "unprognostic (1.33e-1)" "unprognostic (4.87e-2)" "unprognostic (1.52e-1)" "unprognostic (1.12e-2)" "unprognostic (1.30e-2)" "unprognostic (2.20e-1)" "unprognostic (5.84e-3)" "unprognostic (1.24e-1)" "unprognostic (1.75e-1)" "unprognostic (2.57e-2)" "unprognostic (3.51e-2)" "unprognostic (1.11e-2)" "unprognostic (5.86e-2)" "unprognostic (4.19e-3)" "unprognostic (2.20e-2)" NR3C2 "MLR, MR" ENSG00000151623 "Nuclear receptor subfamily 3 group C member 2" P08235 4 148078762-148444698 "Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 810.0;Distal convoluted tubule cells: 1221.3;Goblet cells: 857.5;Renal collecting duct intercalated cells: 1124.3;Renal connecting tubule cells: 1490.5;Somatotrophs: 1145.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 27.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 1.8" "Lineage enriched" "Detected in single" 6 "T-cells: 1.8" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Minor Salivary Gland - Minor salivary gland ductal cells, Spleen - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009155, HPA074979" Enhanced Supported Nucleoplasm NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 76: Non-specific - Metabolism" "Cluster 29: Forebrain - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 11 Nucleoplasm "CAB009155: , HPA074979: " "unprognostic (6.05e-2)" "unprognostic (1.33e-2)" "unprognostic (1.62e-1)" "unprognostic (1.70e-3)" "unprognostic (3.65e-2)" "unprognostic (5.80e-3)" "unprognostic (1.12e-1)" "unprognostic (1.71e-2)" "unprognostic (8.19e-2)" "validated prognostic favorable (3.39e-10)" "validated prognostic favorable (6.82e-5)" "unprognostic (2.58e-3)" "unprognostic (8.48e-3)" "potential prognostic favorable (1.74e-5)" "unprognostic (9.93e-3)" "unprognostic (5.46e-2)" "unprognostic (3.64e-1)" "unprognostic (3.14e-1)" "unprognostic (1.10e-1)" "unprognostic (4.04e-2)" "unprognostic (1.22e-2)" "unprognostic (2.16e-1)" "unprognostic (1.72e-1)" "unprognostic (7.13e-2)" "unprognostic (1.04e-2)" "unprognostic (1.30e-1)" "unprognostic (8.73e-2)" "unprognostic (6.98e-2)" NR4A1 "GFRP1, HMR, N10, NAK-1, NGFIB, NUR77, TR3" ENSG00000123358 "Nuclear receptor subfamily 4 group A member 1" P22736 12 52022832-52059507 "Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Inflammatory response, Transcription, Transcription regulation" "DNA-binding, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast secretory cells: 820.7;Endometrial luminal cells: 1029.1;Epicardial cells: 1491.8;Ovarian stromal cells: 1172.8;Vascular smooth muscle cells: 825.0" "Cell type enhanced" "Detected in all" "endothelial cell: 259.2;vascular associated smooth muscle cell: 497.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "intermediate monocyte: 36.7;non-classical monocyte: 54.4" "Lineage enriched" "Detected in many" 15 "monocytes: 54.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027311, HPA059742, HPA070142" Approved Supported "Nucleoplasm,Nuclear membrane,Nucleoli fibrillar center,Nuclear speckles,Cytosol" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 15: Non-specific - Transcription" "Cluster 7: Liver cancer - Metabolism" "Cluster 103: Non-specific - Basic cellular processes" 48 Nucleoplasm "Nuclear membrane, Nucleoli fibrillar center, Nuclear speckles, Cytosol" "HPA027311: , HPA059742: , HPA070142: " "unprognostic (1.09e-1)" "unprognostic (1.10e-1)" "unprognostic (1.31e-2)" "unprognostic (1.36e-1)" "unprognostic (8.26e-2)" "unprognostic (2.93e-1)" "unprognostic (1.07e-1)" "unprognostic (1.57e-1)" "unprognostic (1.25e-1)" "unprognostic (7.08e-3)" "unprognostic (1.21e-3)" "potential prognostic favorable (1.61e-6)" "unprognostic (1.00e-1)" "unprognostic (3.56e-2)" "unprognostic (1.54e-2)" "unprognostic (3.49e-1)" "unprognostic (3.10e-3)" "unprognostic (7.85e-2)" "unprognostic (7.26e-2)" "unprognostic (1.78e-3)" "unprognostic (8.72e-3)" "unprognostic (1.93e-1)" "unprognostic (9.92e-2)" "unprognostic (9.25e-2)" "unprognostic (1.79e-1)" "potential prognostic favorable (3.56e-6)" "unprognostic (9.95e-3)" "unprognostic (3.63e-2)" "unprognostic (1.59e-1)" "unprognostic (9.48e-3)" "unprognostic (5.86e-2)" NR4A2 "HZF-3, NOT, NURR1, RNR1, TINUR" ENSG00000153234 "Nuclear receptor subfamily 4 group A member 2" P43354 2 156324437-156342348 "Cancer-related genes, Disease related genes, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, Disease variant, Dystonia, Intellectual disability, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 125.3;bone marrow: 126.4;ovary: 122.1" "Cell type enhanced" "Detected in many" "cDC: 694.3;Endometrial luminal cells: 698.0;Macrophages: 523.7;Mast cells: 793.5;monocytes: 675.4;NK-cells: 505.6;Ovarian stromal cells: 469.3;T-cells: 484.9" "Cell type enhanced" "Detected in many" "vascular associated smooth muscle cell: 153.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 6.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000543, CAB010481" Uncertain Supported "Nuclear speckles" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 15: Bone marrow - Innate immune response" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 7: Liver cancer - Metabolism" "Cluster 103: Non-specific - Basic cellular processes" 8 "Nuclear speckles" "CAB010481: , HPA000543: " "unprognostic (1.53e-1)" "unprognostic (1.76e-1)" "unprognostic (1.58e-1)" "unprognostic (4.61e-2)" "unprognostic (3.76e-2)" "unprognostic (1.73e-1)" "unprognostic (7.00e-2)" "unprognostic (2.49e-1)" "unprognostic (1.11e-2)" "unprognostic (1.76e-1)" "unprognostic (6.56e-2)" "unprognostic (9.94e-3)" "unprognostic (3.76e-1)" "unprognostic (1.41e-1)" "unprognostic (1.91e-2)" "unprognostic (4.93e-2)" "unprognostic (7.29e-2)" "unprognostic (1.95e-2)" "unprognostic (1.40e-1)" "unprognostic (1.20e-2)" "unprognostic (5.72e-2)" "unprognostic (1.94e-2)" "unprognostic (1.68e-2)" "unprognostic (1.49e-1)" "unprognostic (9.59e-2)" "potential prognostic favorable (3.07e-5)" "unprognostic (1.06e-1)" "unprognostic (4.40e-2)" "unprognostic (2.76e-2)" "unprognostic (1.38e-2)" "unprognostic (8.39e-2)" NR4A3 "CHN, CSMF, MINOR, NOR1" ENSG00000119508 "Nuclear receptor subfamily 4 group A member 3" Q92570 9 99821855-99866891 "Cancer-related genes, Disease related genes, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "cDC: 701.7;Epicardial cells: 857.4;Innate lymphoid cells: 444.8;Macrophages: 412.7;Mast cells: 738.8;monocytes: 566.6;Neutrophils: 549.6;pDCs: 810.4;Pituicytes/FSCs: 773.9" "Cell type enhanced" "Detected in all" "ependymal cell: 176.2;vascular associated smooth muscle cell: 160.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "cervical cancer: 7.3;skin cancer: 12.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043360 Uncertain NA NA "Cluster 24: Non-specific - Transcription" "Cluster 29: Forebrain - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 103: Non-specific - Basic cellular processes" 33 "HPA043360: " "unprognostic (1.52e-1)" "unprognostic (1.02e-3)" "unprognostic (5.44e-2)" "unprognostic (2.76e-2)" "unprognostic (4.53e-1)" "unprognostic (1.86e-2)" "unprognostic (3.32e-1)" "unprognostic (4.09e-1)" "unprognostic (8.60e-2)" "unprognostic (6.12e-2)" "unprognostic (5.59e-3)" "unprognostic (3.12e-3)" "unprognostic (4.43e-1)" "unprognostic (2.30e-2)" "unprognostic (2.48e-1)" "unprognostic (2.90e-1)" "unprognostic (6.28e-3)" "unprognostic (2.67e-1)" "unprognostic (7.46e-3)" "unprognostic (9.52e-2)" "unprognostic (1.97e-1)" "unprognostic (3.54e-1)" "unprognostic (3.48e-1)" "unprognostic (3.84e-1)" "potential prognostic favorable (3.34e-4)" "potential prognostic favorable (3.00e-4)" "potential prognostic unfavorable (3.82e-4)" "unprognostic (2.41e-2)" "unprognostic (2.93e-2)" NR5A1 "AD4BP, ELP, FTZ1, FTZF1, hSF-1, SF-1, SF1" ENSG00000136931 "Nuclear receptor subfamily 5 group A member 1" Q13285 9 124481236-124507420 "Disease related genes, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Disease variant, Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adrenal gland: 182.1;lymphoid tissue: 136.6" "Cell type enhanced" "Detected in some" "Adrenal cortex cells: 89.5;Adrenal medulla cells: 10.6;Gonadotrophs: 100.0;Granulosa cells: 23.5;Leydig cells: 25.4;Lymphatic endothelial cells: 15.1;Ovarian stromal cells: 19.1;Peritubular myoid cells: 16.0;Platelets: 11.3;Sertoli cells: 17.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Ovary Serous Cystadenocarcinoma (TCGA): 4.1;Testicular Germ Cell Tumor (TCGA): 4.8" "Region enriched" "Detected in single" 50 "hypothalamus: 37.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "head and neck cancer: 1.9;Leukemia: 3.2;liver cancer: 3.7" "Adrenal gland - Adrenal cortex cells, Pituitary gland - Gonadotropes, Spleen - Endothelial cells" "Region enriched" "Detected in single" 52 "hypothalamus: 5.2" "Region enriched" "Detected in single" 8 "hypothalamus: 1.6" HPA079181 Supported Nucleoplasm,Cytosol NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 47: Leukemia - Hemostasis" "Cluster 18: Adrenal cortex cells - Steroidogensis" 20 Nucleoplasm Cytosol "HPA079181: " "unprognostic (2.13e-1)" "unprognostic (6.37e-2)" "unprognostic (2.65e-2)" "unprognostic (3.33e-2)" "unprognostic (4.39e-2)" "unprognostic (6.60e-2)" NR5A2 "B1F2, FTF, FTZ-F1, FTZ-F1beta, hB1F, hB1F-2, LRH-1, LRH1" ENSG00000116833 "Nuclear receptor subfamily 5 group A member 2" O00482 1 200027614-200177420 "Nuclear receptors, Predicted intracellular proteins, Transcription factors, Transporters" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 16.8;liver: 36.1;pancreas: 57.7" "Cell type enhanced" "Detected in many" "Cholangiocytes: 288.7;Colonocytes: 246.8;Enteric stem cells: 220.7;Enteric transient amplifying cells: 244.1;Enterocytes: 457.6;Gastric progenitor cells: 147.4;Granulosa cells: 178.4;Hepatocytes: 270.3;Pancreatic acinar cells: 1501.6;Pancreatic duct cells: 424.0;Paneth cells: 185.6;Vascular endothelial cells: 192.6" "Cell type enriched" "Detected in some" 5 "endothelial cell: 20.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.3" "Lineage enriched" "Detected in single" 5 "granulocytes: 2.3" "Cancer enhanced" "Detected in many" "cervical cancer: 12.2" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Minor Salivary Gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells" "Region enhanced" "Detected in single" "hypothalamus: 1.2" "Low region specificity" "Detected in many" "HPA005455, HPA017067" Approved Uncertain "Nuclear speckles" NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 24: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 5: Pancreatic acinar cells - Pancreatic exocrine secretion" 10 "Nuclear speckles" "HPA005455: , HPA017067: " "unprognostic (1.13e-1)" "unprognostic (1.57e-1)" "unprognostic (2.52e-1)" "unprognostic (3.76e-3)" "unprognostic (1.20e-3)" "unprognostic (1.89e-1)" "unprognostic (2.07e-1)" "unprognostic (1.35e-1)" "potential prognostic favorable (3.32e-4)" "unprognostic (1.13e-2)" "unprognostic (2.76e-2)" "unprognostic (6.04e-2)" "unprognostic (1.22e-1)" "unprognostic (7.72e-2)" "unprognostic (8.21e-2)" "unprognostic (9.05e-2)" "unprognostic (1.34e-1)" "unprognostic (9.22e-2)" "unprognostic (5.98e-2)" "unprognostic (4.37e-1)" "unprognostic (7.90e-3)" "unprognostic (5.97e-3)" "unprognostic (2.68e-1)" "unprognostic (6.08e-2)" "unprognostic (9.39e-2)" "unprognostic (2.01e-1)" "unprognostic (1.93e-1)" NR6A1 "CT150, GCNF, GCNF1, RTR" ENSG00000148200 "Nuclear receptor subfamily 6 group A member 1" Q15406 9 124517275-124771311 "Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "testis: 21.4" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 1017.9;Pituitary stem cells: 554.8;Retinal horizontal cells: 669.1;Sertoli cells: 924.6" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 17 "Testicular Germ Cell Tumor (TCGA): 44.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "eosinophil: 1.2;neutrophil: 4.8" "Lineage enriched" "Detected in single" 7 "granulocytes: 4.8" "Cancer enhanced" "Detected in all" "testis cancer: 20.0" "Pituitary gland - Corticotropes, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA031461, HPA045145" Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 57: Testis - Spermatogenesis" "Cluster 23: Choroid plexus - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 101: Choroid plexus epithelial cells - Ion transport" Nucleoplasm "Centrosome, Cytosol" "HPA031461: , HPA045145: " "unprognostic (2.64e-1)" "unprognostic (1.05e-1)" "unprognostic (2.99e-1)" "unprognostic (1.18e-1)" "unprognostic (2.33e-1)" "unprognostic (1.69e-2)" "unprognostic (3.48e-2)" "unprognostic (3.80e-2)" "unprognostic (1.20e-1)" "validated prognostic unfavorable (6.21e-5)" "validated prognostic unfavorable (3.72e-5)" "unprognostic (2.35e-2)" "unprognostic (3.82e-2)" "unprognostic (4.14e-2)" "unprognostic (1.30e-2)" "unprognostic (4.34e-2)" "unprognostic (3.15e-2)" "unprognostic (1.57e-2)" "unprognostic (2.74e-1)" "unprognostic (3.80e-1)" "unprognostic (1.45e-1)" "unprognostic (5.71e-2)" "unprognostic (2.25e-1)" "unprognostic (2.12e-2)" "unprognostic (1.35e-3)" NRAP ENSG00000197893 "Nebulin related anchoring protein" Q86VF7 10 113588714-113664070 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "skeletal muscle: 2213.4;tongue: 1069.5" "Group enriched" "Detected in some" 39 "Cardiomyocytes: 632.9;Myonuclei: 1072.1;Thymic myoid cells: 425.6" "Cell type enhanced" "Detected in some" "deep-layer intratelencephalic: 1.6;thalamic excitatory: 1.2" "Group enriched" "Detected in some" 6 "Head and Neck Squamous Cell Carcinoma (TCGA): 12.4;Prostate Adenocarcinoma (TCGA): 4.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA037953, HPA037954, HPA075074" Enhanced Approved "Vesicles,Intermediate filaments,Cytosol" NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 53: Neurons - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 55: Myocytes - Oxidative muscle function" 4 "Intermediate filaments" "Vesicles, Cytosol" "HPA037953: , HPA037954: , HPA075074: " "unprognostic (3.68e-2)" "unprognostic (1.71e-3)" "unprognostic (1.07e-1)" "unprognostic (1.77e-1)" NRARP MGC61598 ENSG00000198435 "NOTCH regulated ankyrin repeat protein" Q7Z6K4 9 137299631-137302271 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 44.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 144.1;Colonocytes: 151.7;Enteric stem cells: 127.8;Enteric transient amplifying cells: 118.3;Esophageal suprabasal cells: 121.7;Fallopian secretory cells: 111.1;Ocular epithelial cells: 178.4;Prostatic club cells: 178.0;Prostatic hillock cells: 156.6;Suprabasal keratinocytes: 381.2" "Cell type enhanced" "Detected in many" "astrocyte: 64.2;vascular associated smooth muscle cell: 220.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 51.1" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Prostate - Urothelial cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025729 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 77: Intestine - Digestion" "Cluster 46: Brainstem - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 85: Squamous epithelial cells - Keratinization" 1 Cytosol Nucleoplasm "HPA025729: " "unprognostic (5.50e-2)" "unprognostic (1.47e-2)" "unprognostic (1.45e-1)" "unprognostic (1.46e-2)" "unprognostic (6.43e-2)" "unprognostic (1.94e-2)" "unprognostic (1.34e-1)" "unprognostic (8.03e-3)" "unprognostic (4.54e-2)" "unprognostic (1.30e-1)" "unprognostic (1.53e-2)" "unprognostic (1.19e-3)" "potential prognostic unfavorable (3.34e-4)" "unprognostic (9.33e-2)" "unprognostic (6.81e-2)" "unprognostic (3.36e-2)" "unprognostic (4.96e-2)" "unprognostic (1.95e-1)" "unprognostic (1.31e-1)" "unprognostic (1.44e-1)" "unprognostic (7.94e-2)" "unprognostic (4.73e-2)" "unprognostic (3.91e-2)" "unprognostic (7.61e-2)" "unprognostic (4.09e-2)" "unprognostic (3.26e-1)" "unprognostic (2.49e-2)" "unprognostic (8.71e-3)" "unprognostic (1.52e-1)" "unprognostic (1.74e-2)" "unprognostic (1.08e-1)" NRAS N-ras ENSG00000213281 "NRAS proto-oncogene, GTPase" P01111 1 114704469-114716771 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" Hydrolase "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 86.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010157, HPA049830, HPA072761, CAB079912" Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 27: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 151 "Plasma membrane" Cytosol "CAB010157: , CAB079912: , HPA049830: , HPA072761: " "unprognostic (1.56e-2)" "unprognostic (1.83e-1)" "unprognostic (2.21e-2)" "unprognostic (5.90e-2)" "unprognostic (9.31e-3)" "unprognostic (3.69e-1)" "unprognostic (9.12e-2)" "unprognostic (4.56e-1)" "unprognostic (3.75e-1)" "potential prognostic unfavorable (1.11e-6)" "potential prognostic favorable (3.94e-7)" "unprognostic (6.93e-2)" "unprognostic (7.26e-2)" "validated prognostic unfavorable (1.92e-6)" "validated prognostic unfavorable (2.91e-4)" "potential prognostic unfavorable (5.75e-4)" "unprognostic (4.63e-3)" "unprognostic (1.46e-1)" "unprognostic (1.50e-1)" "unprognostic (1.36e-3)" "unprognostic (2.96e-2)" "unprognostic (1.76e-3)" "unprognostic (2.68e-2)" "unprognostic (2.27e-3)" "unprognostic (1.88e-3)" "unprognostic (4.84e-2)" "unprognostic (6.42e-2)" "unprognostic (4.99e-1)" "unprognostic (1.80e-1)" "unprognostic (8.08e-3)" "unprognostic (1.23e-1)" NRBF2 "COPR1, COPR2, DKFZp564C1664, FLJ30395" ENSG00000148572 "Nuclear receptor binding factor 2" Q96F24 10 63133247-63155031 "Predicted intracellular proteins" "Autophagy, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 544.3;Syncytiotrophoblasts: 390.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "neutrophil: 690.1" "Lineage enriched" "Detected in all" 7 "granulocytes: 690.1" "Low cancer specificity" "Detected in all" "Spleen - Neutrophils_2, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021670, HPA059477" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 24: Neutrophils - Innate immunity signal integration" 33 "Nucleoplasm, Cytosol" "HPA021670: , HPA059477: " "unprognostic (1.49e-2)" "unprognostic (8.11e-2)" "unprognostic (1.54e-1)" "unprognostic (3.06e-1)" "unprognostic (9.68e-2)" "unprognostic (3.29e-2)" "unprognostic (2.68e-2)" "unprognostic (3.18e-3)" "unprognostic (1.02e-1)" "unprognostic (2.62e-3)" "unprognostic (2.72e-3)" "unprognostic (2.59e-1)" "unprognostic (1.89e-1)" "unprognostic (2.79e-2)" "unprognostic (2.71e-1)" "unprognostic (5.15e-2)" "unprognostic (7.26e-2)" "unprognostic (2.70e-1)" "unprognostic (1.22e-2)" "unprognostic (3.43e-2)" "potential prognostic unfavorable (7.05e-4)" "unprognostic (7.28e-3)" "potential prognostic unfavorable (8.49e-4)" "unprognostic (7.12e-3)" "unprognostic (2.20e-2)" "unprognostic (4.10e-3)" "unprognostic (3.79e-1)" "unprognostic (1.53e-1)" "unprognostic (1.15e-2)" "unprognostic (1.09e-3)" "unprognostic (1.61e-1)" NRBP1 "BCON3, MADM, MUDPNP, NRBP" ENSG00000115216 "Nuclear receptor binding protein 1" Q9UHY1 2 27427790-27442259 "Enzymes, Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 318.0;Esophageal apical cells: 527.3;Extravillous trophoblasts: 331.5;Syncytiotrophoblasts: 248.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029527, CAB033078" Supported Supported Cytosol NA NA 33000 "Cluster 35: Neutrophils - Protein binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 42 Cytosol "CAB033078: , HPA029527: " "unprognostic (1.98e-1)" "potential prognostic unfavorable (1.51e-4)" "unprognostic (1.51e-1)" "unprognostic (7.51e-2)" "unprognostic (2.64e-1)" "unprognostic (1.06e-2)" "unprognostic (2.45e-2)" "unprognostic (2.82e-1)" "unprognostic (1.86e-1)" "unprognostic (8.30e-2)" "unprognostic (9.07e-3)" "unprognostic (1.48e-2)" "unprognostic (3.88e-2)" "validated prognostic unfavorable (1.59e-5)" "validated prognostic unfavorable (1.96e-4)" "unprognostic (2.32e-3)" "unprognostic (1.90e-3)" "unprognostic (1.33e-1)" "unprognostic (2.41e-1)" "unprognostic (2.27e-1)" "unprognostic (1.70e-2)" "unprognostic (5.22e-2)" "unprognostic (2.86e-2)" "unprognostic (1.65e-1)" "unprognostic (2.51e-1)" "unprognostic (1.95e-1)" "unprognostic (8.68e-2)" "unprognostic (1.54e-1)" "unprognostic (2.77e-1)" "unprognostic (1.31e-1)" "unprognostic (2.99e-1)" NRBP2 DKFZp434P086 ENSG00000185189 "Nuclear receptor binding protein 2" Q9NSY0 8 143833583-143840973 "Enzymes, Predicted intracellular proteins" Neurogenesis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 95.2" "Cell type enhanced" "Detected in many" "Astrocytes: 91.4;Bergmann glia: 57.3;Ependymal cells: 83.6;Oligodendrocytes: 56.8;Tuft cells: 46.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020944, HPA029051, HPA029052" Approved Approved Cytosol NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 27: Breast cancer - Unknown function" "Cluster 28: Astrocytes - Homeostasis & neuron support" 14 Cytosol "CAB020944: , HPA029051: , HPA029052: " "unprognostic (1.96e-3)" "unprognostic (8.50e-2)" "unprognostic (3.30e-1)" "unprognostic (1.39e-1)" "unprognostic (3.34e-2)" "unprognostic (2.21e-1)" "unprognostic (1.72e-1)" "unprognostic (3.84e-1)" "unprognostic (2.40e-2)" "unprognostic (5.12e-2)" "unprognostic (1.39e-1)" "unprognostic (3.11e-2)" "unprognostic (2.13e-1)" "unprognostic (3.54e-1)" "potential prognostic favorable (1.29e-4)" "unprognostic (1.75e-1)" "unprognostic (2.74e-1)" "unprognostic (1.75e-1)" "unprognostic (1.42e-1)" "unprognostic (3.71e-1)" "unprognostic (5.80e-2)" "unprognostic (3.69e-2)" "potential prognostic unfavorable (2.39e-4)" "unprognostic (1.88e-1)" "unprognostic (1.26e-1)" "unprognostic (1.52e-1)" "unprognostic (1.96e-1)" "unprognostic (5.96e-2)" "unprognostic (1.50e-1)" "unprognostic (1.40e-1)" "unprognostic (8.95e-2)" NRCAM "Bravo, KIAA0343" ENSG00000091129 "Neuronal cell adhesion molecule" Q92823 7 108147623-108456717 "Disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 35.1;brain: 101.7;retina: 34.8" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 1220.5;Adrenal medulla cells: 542.5;Astrocytes: 935.1;Bergmann glia: 1268.7;Brain excitatory neurons: 588.9;Cone photoreceptor cells: 743.2;Corticotrophs: 769.9;Lactotrophs: 703.3;Oligodendrocyte progenitor cells: 1948.9;Pituitary stem cells: 2103.7;Somatotrophs: 570.3;Thyrotrophs: 747.3" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 6 "Glioblastoma Multiforme (TCGA): 79.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "naive CD8 T-cell: 2.1" "Lineage enriched" "Detected in single" 15 "T-cells: 2.1" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Pituitary gland - Lactotropes, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012606, CAB080588" Approved Supported "Nucleoplasm,Vesicles,Plasma membrane,Primary cilium,Cytosol" "Secreted in brain" "Cell adhesion" NA NA 39000000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 73: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 72: Neuronal - Signal transduction" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 1 Nucleoplasm "Vesicles, Plasma membrane, Primary cilium, Cytosol" "CAB080588: , HPA012606: " "unprognostic (1.75e-1)" "unprognostic (4.03e-1)" "unprognostic (2.17e-1)" "unprognostic (1.44e-1)" "unprognostic (2.31e-2)" "unprognostic (2.78e-1)" "unprognostic (2.95e-2)" "unprognostic (6.59e-3)" "unprognostic (3.11e-2)" "unprognostic (1.16e-3)" "potential prognostic favorable (6.74e-6)" "unprognostic (4.36e-3)" "unprognostic (1.35e-1)" "unprognostic (1.76e-3)" "unprognostic (1.76e-2)" "unprognostic (7.92e-2)" "unprognostic (2.10e-1)" "unprognostic (4.16e-3)" "unprognostic (4.21e-2)" "unprognostic (4.14e-1)" "unprognostic (5.67e-2)" "unprognostic (1.80e-2)" "unprognostic (2.81e-2)" "unprognostic (1.19e-1)" "unprognostic (1.80e-1)" "unprognostic (3.11e-2)" "unprognostic (3.63e-3)" "unprognostic (3.39e-1)" "unprognostic (1.57e-1)" "unprognostic (2.89e-1)" NRDC "hNRD1, hNRD2, NRD1" ENSG00000078618 "Nardilysin convertase" O43847 1 51789191-51878805 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 266.0" "Cell type enhanced" "Detected in all" "Early spermatids: 757.2;Late spermatids: 2895.0;Neutrophils: 1166.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053661 Approved Nucleoplasm NA NA 21000 "Cluster 21: Neutrophils - Unknown function" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 27: Non-specific - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 24: Neutrophils - Innate immunity signal integration" 10 Nucleoplasm "HPA053661: " "unprognostic (7.82e-2)" "unprognostic (1.30e-1)" "unprognostic (2.10e-1)" "unprognostic (1.15e-3)" "unprognostic (1.05e-1)" "unprognostic (1.83e-1)" "unprognostic (3.48e-2)" "unprognostic (1.69e-1)" "potential prognostic unfavorable (3.35e-4)" "unprognostic (2.96e-3)" "unprognostic (2.98e-1)" "unprognostic (2.07e-1)" "potential prognostic unfavorable (7.37e-7)" "unprognostic (1.80e-2)" "unprognostic (9.30e-2)" "unprognostic (2.10e-1)" "unprognostic (6.86e-3)" "unprognostic (6.24e-2)" "unprognostic (1.69e-1)" "unprognostic (7.38e-3)" "unprognostic (3.49e-2)" "unprognostic (3.80e-1)" "unprognostic (6.63e-2)" "unprognostic (1.08e-1)" "unprognostic (1.24e-1)" "unprognostic (2.08e-1)" "unprognostic (1.52e-1)" "unprognostic (2.75e-2)" "unprognostic (1.30e-2)" NRDE2 "C14orf102, FLJ14051" ENSG00000119720 "NRDE-2, necessary for RNA interference, domain containing" Q9H7Z3 14 90267860-90331969 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, Mitosis, mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047050, HPA050583" Uncertain Supported Nucleoplasm,Mitochondria NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 61: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 9 "Nucleoplasm, Mitochondria" "HPA047050: , HPA050583: " "unprognostic (4.30e-3)" "unprognostic (1.48e-1)" "unprognostic (2.43e-1)" "unprognostic (7.17e-2)" "unprognostic (2.34e-2)" "unprognostic (3.38e-1)" "unprognostic (8.07e-2)" "potential prognostic favorable (1.93e-4)" "potential prognostic favorable (9.25e-4)" "unprognostic (1.42e-1)" "unprognostic (9.49e-2)" "unprognostic (3.20e-2)" "unprognostic (9.36e-2)" "unprognostic (8.29e-2)" "unprognostic (7.64e-3)" "unprognostic (2.00e-3)" "unprognostic (4.12e-3)" "unprognostic (9.54e-2)" "unprognostic (1.32e-1)" "unprognostic (7.08e-2)" "unprognostic (3.06e-1)" "unprognostic (5.75e-2)" "unprognostic (5.05e-2)" "unprognostic (4.58e-1)" NREP "C5orf13, D4S114, P311, PRO1873, PTZ17, SEZ17" ENSG00000134986 "Neuronal regeneration related protein" Q16612 5 111662621-111997464 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 419.7" "Cell type enhanced" "Detected in all" "Adrenal cortex cells: 146.2;Brain excitatory neurons: 172.9;Choroid plexus epithelial cells: 239.2;Cytotrophoblasts: 175.7;Myonuclei: 206.6;Retinal amacrine cells: 181.8;Thymocytes: 163.5" "Cell type enhanced" "Detected in all" "upper rhombic lip: 391.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "myeloid DC: 24.7;NK-cell: 6.9;plasmacytoid DC: 25.2" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Neuroblastoma: 300.3" "Adipose subcutaneous - Adipose progenitor cells, Colon - Enteric glia cells, Minor Salivary Gland - Fibroblasts, Skeletal muscle - Skeletal myocytes, Skin - Fibroblasts_1, Thyroid gland - Fibroblasts" "Region enriched" "Detected in all" 5 "cerebellum: 1766.1" "Region enhanced" "Detected in all" "cerebellum: 822.1" HPA000545 Approved Approved Vesicles NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 27: Cerebellum - Synaptic function" "Cluster 2: Neurons - Nucleosome" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 2 Vesicles "HPA000545: " "unprognostic (3.98e-2)" "unprognostic (3.65e-2)" "unprognostic (6.11e-3)" "unprognostic (3.81e-2)" "unprognostic (2.42e-1)" "unprognostic (1.60e-1)" "unprognostic (8.39e-2)" "unprognostic (1.87e-1)" "unprognostic (4.02e-3)" "unprognostic (1.59e-3)" "unprognostic (5.25e-3)" "unprognostic (4.28e-2)" "unprognostic (6.06e-3)" "unprognostic (9.87e-2)" "unprognostic (1.44e-2)" "unprognostic (1.05e-1)" "unprognostic (3.86e-1)" "unprognostic (3.25e-1)" "unprognostic (5.74e-2)" "unprognostic (4.69e-3)" "unprognostic (2.49e-1)" "unprognostic (3.28e-1)" "unprognostic (1.07e-1)" "unprognostic (4.31e-1)" "potential prognostic unfavorable (8.92e-4)" "unprognostic (1.51e-3)" "unprognostic (1.39e-1)" "unprognostic (2.56e-3)" "unprognostic (7.01e-2)" NRF1 "ALPHA-PAL, EWG" ENSG00000106459 "Nuclear respiratory factor 1" Q16656 7 129611720-129757082 "Essential proteins, Metabolic proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 339.4;Neutrophil progenitors: 381.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pancreas - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029329 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 6: Leukemia - Signal transduction" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 18 Nucleoplasm Cytosol "HPA029329: " "unprognostic (3.05e-2)" "unprognostic (5.05e-2)" "unprognostic (1.82e-1)" "unprognostic (7.11e-2)" "unprognostic (3.28e-2)" "unprognostic (2.30e-1)" "unprognostic (4.54e-1)" "unprognostic (3.25e-3)" "unprognostic (1.75e-2)" "unprognostic (1.29e-2)" "unprognostic (7.44e-3)" "unprognostic (9.59e-3)" "unprognostic (5.36e-2)" "potential prognostic unfavorable (6.21e-4)" "unprognostic (1.45e-1)" "unprognostic (1.12e-1)" "unprognostic (6.38e-3)" "unprognostic (7.44e-2)" "unprognostic (8.40e-2)" "unprognostic (3.16e-1)" "unprognostic (9.16e-3)" "unprognostic (1.64e-2)" "unprognostic (6.48e-3)" "unprognostic (4.02e-2)" "unprognostic (8.68e-2)" "unprognostic (9.34e-3)" "unprognostic (4.48e-2)" "unprognostic (2.68e-1)" "unprognostic (3.17e-1)" "unprognostic (3.86e-2)" "unprognostic (1.29e-1)" NRG1 "GGF, HGL, HRG, NDF, NRG1-IT2" ENSG00000157168 "Neuregulin 1" Q02297 8 31639222-32855666 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 15.9" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 1244.5;Brain excitatory neurons: 1455.5;Brain inhibitory neurons: 1507.9;Cone photoreceptor cells: 1484.3;Gonadotrophs: 1913.2;Lactotrophs: 7015.1;Other brain neurons: 1174.1;Retinal bipolar cells: 1085.0;Retinal ganglion cells: 2008.6;Retinal horizontal cells: 4491.6;Somatotrophs: 1927.0;Thyrotrophs: 4198.3" "Cell type enhanced" "Detected in all" "eccentric medium spiny neuron: 5760.1;lower rhombic lip: 10642.2" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 25.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "classical monocyte: 53.9" "Lineage enriched" "Detected in many" 5 "monocytes: 53.9" "Low cancer specificity" "Detected in many" "Breast - Breast myoepithelial cells, Lung - Alveolar cells type 1, Prostate - Prostate basal glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010964 Uncertain Approved Nucleoplasm "Secreted to blood" "Growth factor" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 5 Nucleoplasm "HPA010964: " "unprognostic (3.94e-2)" "unprognostic (5.55e-2)" "unprognostic (2.19e-1)" "unprognostic (3.66e-1)" "unprognostic (2.26e-3)" "unprognostic (3.54e-1)" "potential prognostic unfavorable (3.48e-5)" "unprognostic (4.66e-1)" "unprognostic (9.16e-2)" "unprognostic (9.16e-3)" "potential prognostic favorable (1.18e-4)" "unprognostic (5.24e-1)" "potential prognostic unfavorable (8.19e-4)" "unprognostic (3.04e-2)" "unprognostic (1.47e-1)" "unprognostic (2.00e-1)" "unprognostic (3.52e-1)" "unprognostic (1.06e-1)" "unprognostic (4.35e-2)" "unprognostic (7.08e-2)" "unprognostic (4.78e-2)" "unprognostic (1.91e-1)" "potential prognostic unfavorable (3.77e-4)" "unprognostic (3.93e-2)" "unprognostic (5.59e-2)" "unprognostic (1.90e-1)" "unprognostic (6.24e-2)" "unprognostic (2.23e-1)" "unprognostic (6.53e-2)" "unprognostic (2.41e-1)" NRG2 "Don-1, HRG2, NTAK" ENSG00000158458 "Neuregulin 2" O14511 5 139846779-140043299 "Cancer-related genes, Predicted membrane proteins, Predicted secreted proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.6" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 176.6;Brain inhibitory neurons: 208.6;Ependymal cells: 161.9;Oligodendrocyte progenitor cells: 201.7;Other brain neurons: 131.2;Retinal amacrine cells: 191.9;Salivary acinar cells: 151.6;Thyrotrophs: 186.7" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Kidney Chromophobe (TCGA): 11.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038935, HPA047973" Approved Supported Nucleoplasm,Nucleoli "Secreted in other tissues" "Growth factor" No NA "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 82: Dendritic cells - Antigen presentation" 3 Nucleoplasm Nucleoli "HPA038935: , HPA047973: " "unprognostic (1.11e-1)" "unprognostic (1.30e-1)" "unprognostic (1.30e-2)" "unprognostic (6.02e-2)" "unprognostic (3.16e-2)" "unprognostic (1.13e-1)" "unprognostic (1.46e-1)" "unprognostic (2.07e-1)" NRG3 ENSG00000185737 "Neuregulin 3" P56975 10 81875194-82987179 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 15.8;retina: 4.8" "Cell type enhanced" "Detected in many" "Astrocytes: 5328.1;Bergmann glia: 2901.0;Brain excitatory neurons: 3001.3;Brain inhibitory neurons: 2587.2;Choroid plexus epithelial cells: 1548.5;Corticotrophs: 3415.1;Ependymal cells: 3009.9;Fallopian secretory cells: 1487.7;Oligodendrocyte progenitor cells: 1468.0;Other brain neurons: 2880.5;Pituitary stem cells: 3416.9;Retinal amacrine cells: 2551.9;Retinal bipolar cells: 2194.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 6.2;Skin Cutaneous Melanoma (TCGA): 5.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 2.1;skin cancer: 2.9" "Adipose subcutaneous - Smooth muscle cells, Breast - Breast glandular cells (progenitors), Liver - Vascular endothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Corticotropes, Skin - Eccrine sweat gland cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075789 Uncertain Vesicles "Secreted in brain" "Growth factor" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 6: Leukemia - Signal transduction" "Cluster 28: Astrocytes - Homeostasis & neuron support" Vesicles "HPA075789: " "unprognostic (6.39e-2)" "unprognostic (5.53e-1)" "potential prognostic favorable (7.78e-4)" "unprognostic (2.61e-1)" "potential prognostic favorable (6.98e-5)" "unprognostic (2.61e-3)" "unprognostic (4.02e-2)" "unprognostic (1.35e-1)" "unprognostic (2.44e-1)" "unprognostic (1.87e-1)" "unprognostic (7.45e-2)" "unprognostic (6.04e-2)" "unprognostic (1.40e-1)" NRG4 HRG4 ENSG00000169752 "Neuregulin 4" Q8WWG1 15 75935969-76059795 "Predicted membrane proteins, Predicted secreted proteins" "Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 8.9;pancreas: 5.0" "Cell type enhanced" "Detected in many" "Ependymal cells: 326.4;Foveolar cells: 113.6;Myonuclei: 126.0;Pancreatic acinar cells: 221.8;Prostatic glandular cells: 109.1;Respiratory ciliated cells: 132.2;Rod photoreceptor cells: 111.4;Salivary duct cells: 97.0" "Cell type enhanced" "Detected in all" "ependymal cell: 359.8" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose visceral - Mesothelial cells, Lung - Respiratory ciliated cells, Skeletal muscle - Skeletal myocytes, Stomach - Gastric mucous cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA010957 Uncertain "Secreted to digestive system" "Growth factor" NA NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 2: Neurons - Nucleosome" "Cluster 56: Non-specific - Sensory perception" "Cluster 34: Ciliated cells - Cilia assembly & function" 4 "HPA010957: " "unprognostic (3.55e-2)" "unprognostic (1.64e-1)" "unprognostic (5.59e-3)" "unprognostic (1.15e-1)" "unprognostic (1.27e-1)" NRGN RC3 ENSG00000154146 Neurogranin Q92686 11 124739942-124747210 "Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 38 "brain: 2193.2" "Cell type enriched" "Detected in many" 5 "Platelets: 12504.2" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 79.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "dendritic cells: 1.8;granulocytes: 2.5;monocytes: 3.6" "Cancer enhanced" "Detected in all" "Bone cancer: 72.7" "Lung - Alveolar cells type 2, Minor Salivary Gland - Endothelial cells, Prostate - Endothelial cells" "Group enriched" "Detected in all" 9 "amygdala: 786.7;basal ganglia: 688.3;cerebral cortex: 1222.7;hippocampal formation: 643.7;white matter: 423.1" "Group enriched" "Detected in all" 5 "basal ganglia: 2631.1;cerebral cortex: 3518.6;hippocampal formation: 1840.3" "CAB006908, HPA038171" Enhanced NA NA 4700000 "Cluster 7: Non-specific - Innate immune response" "Cluster 78: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 47: Platelets - Hemostasis" "CAB006908: , HPA038171: " "unprognostic (3.18e-2)" "unprognostic (1.57e-1)" "unprognostic (2.65e-1)" "unprognostic (4.27e-2)" "unprognostic (1.48e-1)" "unprognostic (1.51e-1)" "unprognostic (3.48e-2)" "unprognostic (7.09e-2)" "unprognostic (1.78e-2)" "unprognostic (1.02e-2)" "unprognostic (1.31e-1)" "potential prognostic favorable (1.66e-4)" "unprognostic (1.59e-1)" "unprognostic (5.92e-3)" "unprognostic (3.35e-1)" "unprognostic (5.71e-3)" "unprognostic (4.05e-2)" "unprognostic (1.26e-1)" "unprognostic (2.13e-1)" "unprognostic (4.46e-2)" "unprognostic (1.37e-2)" "potential prognostic favorable (6.83e-4)" "unprognostic (2.97e-1)" "unprognostic (1.15e-1)" "unprognostic (1.25e-1)" "unprognostic (1.46e-1)" "unprognostic (2.64e-3)" "unprognostic (2.97e-1)" "unprognostic (5.63e-2)" "unprognostic (1.11e-1)" "unprognostic (3.65e-1)" NRIP1 RIP140 ENSG00000180530 "Nuclear receptor interacting protein 1" P48552 21 14961235-15065936 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 330.3;Hematopoietic stem cells: 745.8;Megakaryocyte progenitors: 477.6;Microglia: 653.1" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 824.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Adrenal cortex cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029785, HPA046571, HPA060036" Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 2: Neurons - Nucleosome" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 56 "Nucleoplasm, Nucleoli" Cytosol "HPA029785: , HPA046571: , HPA060036: " "unprognostic (3.19e-2)" "unprognostic (1.30e-1)" "unprognostic (3.22e-2)" "unprognostic (9.05e-2)" "unprognostic (1.89e-1)" "unprognostic (1.99e-1)" "unprognostic (1.89e-1)" "unprognostic (7.60e-2)" "unprognostic (1.29e-2)" "unprognostic (9.37e-2)" "potential prognostic favorable (7.26e-5)" "unprognostic (1.91e-1)" "unprognostic (2.71e-2)" "unprognostic (1.96e-1)" "unprognostic (4.07e-2)" "unprognostic (6.35e-2)" "potential prognostic unfavorable (1.57e-5)" "unprognostic (2.44e-3)" "unprognostic (1.18e-1)" "unprognostic (1.44e-1)" "unprognostic (4.02e-2)" "unprognostic (2.84e-2)" "unprognostic (3.19e-2)" "unprognostic (1.08e-1)" "unprognostic (1.25e-2)" "unprognostic (3.09e-1)" "unprognostic (2.19e-2)" "unprognostic (5.44e-2)" "unprognostic (5.94e-2)" "unprognostic (3.79e-1)" "unprognostic (3.24e-2)" NRIP2 DKFZP761G1913 ENSG00000053702 "Nuclear receptor interacting protein 2" Q9BQI9 12 2825348-2835544 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "blood vessel: 16.7;brain: 55.5" "Cell type enhanced" "Detected in many" "Adipocytes: 7.4;Brain excitatory neurons: 8.3;Cardiomyocytes: 41.6;Epicardial cells: 25.0;Fibro-adipogenic progenitors: 7.4;Myonuclei: 8.7;Podocytes: 20.9;Vascular smooth muscle cells: 20.7" "Cell type enhanced" "Detected in many" "upper rhombic lip: 17.8;vascular associated smooth muscle cell: 28.0" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 17.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "basophil: 3.7" "Lineage enriched" "Detected in single" 4 "granulocytes: 3.7" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Heart muscle - Smooth muscle cells, Testis - Peritubular cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039197, HPA039860" Enhanced Approved "Nucleoplasm,Nuclear bodies,Cytosol" Yes No "Cluster 16: Non-specific - Cell proliferation" "Cluster 71: Cerebellum - Nervous system development" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 62: Smooth muscle cells - Muscle contraction" 2 "Nucleoplasm, Cytosol" "Nuclear bodies" "HPA039197: , HPA039860: " "unprognostic (2.38e-1)" "unprognostic (4.60e-2)" "unprognostic (8.03e-2)" "unprognostic (3.60e-2)" "unprognostic (2.27e-3)" "unprognostic (3.58e-1)" "unprognostic (7.60e-2)" "potential prognostic favorable (1.32e-4)" "unprognostic (4.36e-2)" "validated prognostic favorable (7.42e-4)" "validated prognostic favorable (1.32e-4)" "unprognostic (2.19e-1)" "unprognostic (1.24e-1)" "unprognostic (1.05e-1)" "unprognostic (8.10e-3)" "unprognostic (1.43e-1)" "unprognostic (8.81e-2)" "unprognostic (1.52e-1)" "unprognostic (8.37e-2)" "unprognostic (4.69e-2)" "potential prognostic favorable (2.15e-4)" "unprognostic (2.40e-1)" "unprognostic (5.74e-3)" "unprognostic (1.53e-1)" "unprognostic (3.23e-2)" "unprognostic (5.48e-2)" "unprognostic (9.51e-2)" "unprognostic (4.46e-2)" "unprognostic (1.80e-1)" "unprognostic (2.38e-2)" NRIP3 C11orf14 ENSG00000175352 "Nuclear receptor interacting protein 3" Q9NQ35 11 8965682-9005288 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 52.0;retina: 22.6;testis: 40.5" "Cell type enhanced" "Detected in many" "Early spermatids: 543.2;Late primary spermatocytes: 476.8;Late spermatids: 688.7;Retinal horizontal cells: 190.3" "Cell type enhanced" "Detected in all" "CGE interneuron: 202.5;hippocampal CA4: 204.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "basophil: 13.2" "Lineage enriched" "Detected in many" 12 "granulocytes: 13.2" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058827, HPA072961" Approved Approved Cytosol NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 27: Cerebellum - Synaptic function" "Cluster 29: Forebrain - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 109: Neurons - Neuronal signaling" 8 Cytosol "HPA058827: , HPA072961: " "unprognostic (1.09e-1)" "unprognostic (2.78e-1)" "unprognostic (1.12e-1)" "unprognostic (1.02e-1)" "unprognostic (2.45e-2)" "unprognostic (8.96e-2)" "unprognostic (3.32e-2)" "unprognostic (3.28e-1)" "unprognostic (1.58e-1)" "unprognostic (2.46e-1)" "unprognostic (5.97e-2)" "unprognostic (5.07e-2)" "unprognostic (1.42e-1)" "unprognostic (1.33e-2)" "unprognostic (2.06e-2)" "unprognostic (4.82e-3)" "unprognostic (2.99e-2)" "unprognostic (2.77e-2)" "unprognostic (1.99e-2)" "unprognostic (4.30e-2)" "unprognostic (1.73e-1)" "unprognostic (1.34e-1)" "unprognostic (2.36e-2)" "unprognostic (1.67e-1)" NRK DKFZp686A17109 ENSG00000123572 "Nik related kinase" Q7Z2Y5 X 105822539-105958610 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 15.2;ovary: 23.6;placenta: 22.7" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 135.3;Cytotrophoblasts: 295.4;Distal convoluted tubule cells: 144.7;Gonadotrophs: 150.9;Leydig cells: 608.2;Loop of henle epithelial cells: 130.5;Migrating cytotrophoblasts: 133.4;Ovarian stromal cells: 88.1;Peritubular myoid cells: 81.9;Syncytiotrophoblasts: 177.2" "Group enriched" "Detected in some" 7 "Bergmann glia: 30.5;ependymal cell: 31.2" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 11.4" "Region enriched" "Detected in some" 11 "cerebellum: 14.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 8 "testis cancer: 37.3" "Colon - Enteric glia cells, Kidney - Ascending Loop of Henle cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts" "Region enriched" "Detected in single" 28 "cerebellum: 14.2" "Region enhanced" "Detected in all" "cerebellum: 53.1" HPA017238 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 75: Ovary - Mixed function" "Cluster 35: Non-specific - DNA binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 63: Cytotrophoblasts - Basic cellular functions" "Nucleoplasm, Cytosol" "HPA017238: " "potential prognostic unfavorable (5.10e-5)" "unprognostic (3.11e-1)" "unprognostic (6.08e-2)" "unprognostic (7.44e-2)" "unprognostic (5.72e-2)" "unprognostic (6.52e-2)" "unprognostic (4.60e-1)" "unprognostic (4.21e-2)" "unprognostic (1.41e-1)" "unprognostic (1.68e-1)" "unprognostic (5.10e-2)" NRL "D14S46E, NRL-MAF, RP27" ENSG00000129535 "Neural retina leucine zipper" P54845 14 24078662-24115010 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Sensory transduction, Transcription, Transcription regulation, Vision" "Activator, Developmental protein, DNA-binding" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 73 "retina: 294.2" "Cell type enhanced" "Detected in some" "Astrocytes: 8.1;Bergmann glia: 9.3;Brain inhibitory neurons: 4.4;Choroid plexus epithelial cells: 5.8;Distal convoluted tubule cells: 9.9;Ependymal cells: 3.9;Loop of henle epithelial cells: 10.2;Microglia: 9.3;Oligodendrocyte progenitor cells: 5.4;Oligodendrocytes: 5.5;Other brain neurons: 4.7;Papillary tip epithelial cells: 8.6;Podocytes: 5.7;Proximal tubule cells: 12.5;Renal collecting duct intercalated cells: 10.5;Renal collecting duct principal cells: 12.3;Renal connecting tubule cells: 11.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in some" 4 "Uterine cancer: 10.1" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in some" "Not detected" "Not detected" "CAB026066, HPA064599" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 42: Retina - Visual perception" "Cluster 43: Hindbrain - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 2 Nucleoplasm Cytosol "CAB026066: , HPA064599: " "unprognostic (9.44e-2)" "unprognostic (2.81e-2)" "unprognostic (2.03e-2)" "unprognostic (1.50e-3)" "unprognostic (4.97e-2)" "unprognostic (4.78e-1)" "unprognostic (2.12e-3)" "unprognostic (1.05e-1)" "potential prognostic favorable (6.15e-4)" "potential prognostic favorable (1.77e-8)" "unprognostic (1.26e-1)" "unprognostic (2.24e-1)" "unprognostic (5.03e-2)" "unprognostic (3.49e-2)" "unprognostic (1.29e-1)" "unprognostic (2.22e-1)" "unprognostic (1.29e-1)" "unprognostic (2.04e-1)" "unprognostic (6.98e-2)" "unprognostic (3.99e-1)" NRM NRM29 ENSG00000137404 Nurim Q8IXM6 6 30688047-30691420 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Kupffer cells: 1.0;Loop of henle epithelial cells: 1.0;Microglia: 2.0;Monocyte progenitors: 1.7;Oligodendrocyte progenitor cells: 2.1;Renal collecting duct principal cells: 1.1" "Cell type enhanced" "Detected in some" "endothelial cell: 8.9;pericyte: 7.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Prostate - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA072545, HPA073982" Enhanced "Nuclear membrane" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 43: Hindbrain - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 102: Non-specific - Mixed function" 51 "Nuclear membrane" "HPA072545: , HPA073982: " "unprognostic (2.75e-1)" "unprognostic (2.44e-1)" "unprognostic (6.04e-2)" "potential prognostic unfavorable (6.56e-4)" "unprognostic (1.16e-1)" "unprognostic (9.53e-2)" "unprognostic (5.69e-2)" "unprognostic (1.66e-1)" "unprognostic (7.23e-3)" "unprognostic (1.69e-1)" "unprognostic (3.75e-1)" "unprognostic (2.00e-1)" "unprognostic (1.24e-2)" "unprognostic (3.75e-2)" "unprognostic (5.54e-2)" "unprognostic (1.45e-1)" "unprognostic (3.96e-2)" "unprognostic (2.49e-1)" NRN1 NRN ENSG00000124785 "Neuritin 1" Q9NPD7 6 5997999-6007605 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 187.2" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 94.0;Extravillous trophoblasts: 100.5;Lymphatic endothelial cells: 105.1;Oocytes: 36.8;Retinal ganglion cells: 73.4;Schwann cells: 183.6;Smooth muscle cells: 140.5;Thymic myoid cells: 84.3;Vascular endothelial cells: 125.6" "Cell type enhanced" "Detected in all" "hippocampal dentate gyrus: 214.0" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 95.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "MAIT T-cell: 2.6;neutrophil: 2.3" "Group enriched" "Detected in many" 7 "granulocytes: 2.3;T-cells: 2.6" "Cancer enhanced" "Detected in many" "Bone cancer: 90.3" "Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Breast - Endothelial cells, Colon - Enteric glia cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Pancreas - Endothelial cells, Pituitary gland - Corticotropes, Prostate - Endothelial cells, Spleen - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 43000 "Cluster 24: Non-specific - Transcription" "Cluster 27: Cerebellum - Synaptic function" "Cluster 51: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "unprognostic (3.93e-3)" "unprognostic (1.90e-2)" "unprognostic (2.78e-1)" "unprognostic (2.91e-3)" "unprognostic (1.27e-1)" "unprognostic (6.76e-3)" "unprognostic (2.44e-2)" "unprognostic (4.44e-2)" "unprognostic (7.41e-2)" "unprognostic (6.82e-2)" "unprognostic (9.01e-3)" "unprognostic (7.89e-2)" "potential prognostic unfavorable (2.28e-4)" "unprognostic (2.28e-2)" "potential prognostic favorable (8.74e-5)" "unprognostic (3.04e-3)" "unprognostic (4.02e-2)" "unprognostic (1.23e-2)" "unprognostic (3.71e-2)" "unprognostic (2.79e-1)" "unprognostic (1.72e-1)" "unprognostic (1.06e-2)" "unprognostic (1.05e-1)" "unprognostic (3.94e-1)" "unprognostic (1.03e-2)" "unprognostic (7.05e-3)" "unprognostic (4.77e-2)" "unprognostic (2.39e-1)" "unprognostic (2.47e-1)" "unprognostic (2.99e-1)" "unprognostic (1.04e-1)" NRN1L "MRCC2446, UNQ2446" ENSG00000188038 "Neuritin 1 like" Q496H8 16 67884885-67888855 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 25.0" "Cell type enhanced" "Detected in some" "Astrocytes: 3.4;Bergmann glia: 3.0;Brain excitatory neurons: 1.5;Brain inhibitory neurons: 2.0;Choroid plexus epithelial cells: 1.5;Ependymal cells: 1.3;Microglia: 1.1;Migrating cytotrophoblasts: 1.0;Oligodendrocyte progenitor cells: 1.8;Oligodendrocytes: 2.0;Other brain neurons: 2.3;Retinal bipolar cells: 2.3;Retinal pigment epithelial cells: 4.3" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 11.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in some" "testis cancer: 6.3" "Pituitary gland - Corticotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA041761 Uncertain "Secreted - unknown location" "No annotated function" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 34: Testis cancer - Unknown function" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 1 "HPA041761: " "unprognostic (3.05e-2)" "unprognostic (1.19e-3)" "unprognostic (8.26e-2)" "unprognostic (2.07e-1)" "unprognostic (2.20e-1)" "potential prognostic unfavorable (1.38e-5)" "unprognostic (1.52e-1)" "unprognostic (1.27e-1)" "unprognostic (2.00e-1)" "unprognostic (3.95e-1)" "unprognostic (5.43e-3)" "unprognostic (2.21e-2)" "unprognostic (3.85e-1)" "potential prognostic favorable (5.96e-4)" "unprognostic (5.08e-2)" "unprognostic (1.09e-1)" "unprognostic (9.29e-2)" "unprognostic (2.62e-1)" "unprognostic (4.00e-1)" NRP1 "CD304, NRP, VEGF165R" ENSG00000099250 "Neuropilin 1" O14786 10 33177492-33336262 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Angiogenesis, Differentiation, Host-virus interaction, Neurogenesis" "Developmental protein, Heparin-binding, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 546.5;Endometrial stromal cells: 339.2;Fibro-adipogenic progenitors: 371.6;Hofbauer cells: 616.3;Kupffer cells: 469.4;Macrophages: 453.0;Medullary thymic epithelial cells: 410.4;pDCs: 321.7;Pericytes: 357.2;Proximal tubule cells: 611.9;Vascular endothelial cells: 593.1" "Cell type enhanced" "Detected in all" "hippocampal CA4: 1340.3;hippocampal dentate gyrus: 669.1" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 170.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 16 "plasmacytoid DC: 39.4" "Lineage enriched" "Detected in many" 16 "dendritic cells: 39.4" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Adrenal gland - Fibroblasts, Breast - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004511, HPA030278" Approved Uncertain Mitochondria "Secreted in other tissues" Receptor NA NA 270000000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 29: Forebrain - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 32 Mitochondria "CAB004511: , HPA030278: " "unprognostic (1.03e-1)" "unprognostic (3.53e-1)" "unprognostic (2.50e-1)" "potential prognostic unfavorable (2.16e-6)" "unprognostic (2.32e-2)" "unprognostic (1.06e-2)" "unprognostic (2.37e-3)" "unprognostic (2.91e-1)" "unprognostic (2.74e-2)" "unprognostic (3.99e-2)" "validated prognostic favorable (4.67e-7)" "validated prognostic favorable (4.70e-4)" "unprognostic (1.42e-1)" "unprognostic (8.80e-3)" "unprognostic (3.60e-1)" "unprognostic (1.66e-1)" "potential prognostic unfavorable (1.36e-4)" "unprognostic (2.31e-2)" "unprognostic (3.57e-2)" "unprognostic (8.67e-2)" "unprognostic (1.69e-1)" "unprognostic (1.15e-1)" "potential prognostic unfavorable (1.01e-4)" "unprognostic (8.75e-2)" "unprognostic (9.60e-2)" "unprognostic (2.38e-2)" "unprognostic (1.83e-2)" "potential prognostic unfavorable (3.33e-5)" "unprognostic (9.02e-2)" "unprognostic (2.75e-2)" "unprognostic (3.49e-1)" NRP2 VEGF165R2 ENSG00000118257 "Neuropilin 2" O60462 2 205681990-205798133 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Differentiation, Host-virus interaction, Neurogenesis" "Developmental protein, Heparin-binding, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 73.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 145.2;Epididymal basal cells: 153.3;Hofbauer cells: 377.9;Lymphatic endothelial cells: 427.9;Macrophages: 210.5;Smooth muscle cells: 215.8;Transitional alveolar cells: 183.6;Vascular endothelial cells: 150.7" "Cell type enhanced" "Detected in all" "mammillary body: 448.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "skin cancer: 122.1" "Breast - Endothelial cells, Liver - Vascular endothelial cells, Prostate - Smooth muscle cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039980, HPA054974" Enhanced Approved "Nucleoplasm,Vesicles,Plasma membrane" "Secreted in other tissues" Receptor NA NA 28000000 "Cluster 75: Ovary - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 82: Dendritic cells - Antigen presentation" 2 "Vesicles, Plasma membrane" Nucleoplasm "HPA039980: , HPA054974: " "unprognostic (3.32e-2)" "unprognostic (7.02e-2)" "unprognostic (1.37e-1)" "unprognostic (2.56e-1)" "unprognostic (1.18e-2)" "unprognostic (4.12e-2)" "unprognostic (1.96e-1)" "unprognostic (5.25e-2)" "unprognostic (2.80e-2)" "unprognostic (6.22e-3)" "unprognostic (1.90e-2)" "unprognostic (4.99e-3)" "unprognostic (1.06e-2)" "unprognostic (6.40e-2)" "unprognostic (1.14e-2)" "unprognostic (2.63e-2)" "unprognostic (2.41e-3)" "unprognostic (1.12e-1)" "unprognostic (3.24e-1)" "unprognostic (5.31e-3)" "unprognostic (6.36e-2)" "unprognostic (2.89e-3)" "unprognostic (5.78e-2)" "unprognostic (2.72e-1)" "unprognostic (6.58e-2)" "unprognostic (2.30e-3)" "unprognostic (3.26e-3)" "unprognostic (2.67e-3)" "unprognostic (3.39e-2)" "unprognostic (2.12e-2)" "unprognostic (3.04e-1)" NRROS "ELLP3030, GARPL1, LRRC33, MGC50789, UNQ3030" ENSG00000174004 "Negative regulator of reactive oxygen species" Q86YC3 3 196639694-196662004 "Disease related genes, Predicted membrane proteins" "Growth factor binding" "Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 30.8" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 19.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 4.2" "Group enriched" "Detected in many" 6 "dendritic cells: 1.3;granulocytes: 4.2;monocytes: 1.1" "Cancer enhanced" "Detected in many" "Leukemia: 76.1;Myeloma: 36.6" "Adrenal gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031586 Uncertain NA NA "Cluster 41: Basophils - Unknown function" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 1 "HPA031586: " "unprognostic (2.30e-1)" "unprognostic (3.76e-2)" "unprognostic (1.05e-1)" "unprognostic (7.88e-2)" "unprognostic (1.00e-1)" "unprognostic (1.56e-1)" "unprognostic (3.51e-1)" "unprognostic (1.11e-2)" "unprognostic (6.63e-2)" "potential prognostic favorable (2.74e-4)" "unprognostic (1.19e-2)" "unprognostic (5.26e-2)" "unprognostic (1.72e-1)" "unprognostic (8.45e-3)" "unprognostic (1.84e-1)" "unprognostic (2.77e-2)" "unprognostic (1.17e-1)" "unprognostic (5.66e-3)" "unprognostic (1.89e-1)" "unprognostic (4.00e-3)" "unprognostic (1.61e-1)" "unprognostic (1.21e-1)" "unprognostic (9.34e-2)" "unprognostic (4.29e-2)" "unprognostic (6.77e-2)" "unprognostic (1.56e-1)" "unprognostic (1.07e-2)" "unprognostic (3.72e-2)" "unprognostic (1.57e-1)" NRSN1 "p24, VMP" ENSG00000152954 "Neurensin 1" Q8IZ57 6 24126186-24154900 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 75.2;pituitary gland: 22.0;retina: 20.9" "Cell type enhanced" "Detected in some" "Astrocytes: 49.4;Brain excitatory neurons: 89.9;Brain inhibitory neurons: 150.4;Corticotrophs: 78.0;Gonadotrophs: 140.5;Lactotrophs: 164.4;Oligodendrocyte progenitor cells: 77.9;Other brain neurons: 133.2;Retinal amacrine cells: 92.9;Retinal bipolar cells: 56.4;Retinal horizontal cells: 254.4;Somatotrophs: 79.4;Thyrotrophs: 270.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 23.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 9 "Neuroblastoma: 35.5" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019681, HPA061006" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 43 "Plasma membrane, Cytosol" "HPA019681: , HPA061006: " "unprognostic (5.27e-2)" "unprognostic (8.05e-2)" "unprognostic (3.56e-2)" "unprognostic (4.73e-2)" "unprognostic (1.34e-2)" "unprognostic (8.27e-3)" "unprognostic (5.81e-3)" "unprognostic (1.76e-1)" "unprognostic (2.21e-1)" "unprognostic (6.61e-2)" "unprognostic (5.68e-2)" "unprognostic (2.49e-1)" NRSN2 "C20orf98, dJ1103G7.6" ENSG00000125841 "Neurensin 2" Q9GZP1 20 346782-359660 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 152.5" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 44.0;Early primary spermatocytes: 41.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Minor Salivary Gland - Minor salivary glandular cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015967 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 73: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 98: Neurons - Neurotransmission & signaling" 2 Vesicles "Nucleoplasm, Cytosol" "HPA015967: " "unprognostic (1.34e-1)" "unprognostic (2.54e-1)" "unprognostic (4.14e-2)" "unprognostic (1.76e-1)" "unprognostic (1.91e-2)" "unprognostic (1.72e-1)" "unprognostic (8.78e-2)" "unprognostic (8.61e-3)" "unprognostic (5.60e-2)" "unprognostic (1.03e-2)" "potential prognostic unfavorable (3.67e-4)" "unprognostic (5.14e-2)" "unprognostic (1.06e-2)" "unprognostic (3.39e-2)" "unprognostic (3.20e-3)" "unprognostic (6.25e-2)" "unprognostic (1.69e-1)" "unprognostic (1.47e-2)" "unprognostic (3.29e-1)" "unprognostic (1.69e-1)" "unprognostic (4.70e-2)" "potential prognostic favorable (1.08e-4)" "unprognostic (2.27e-2)" "unprognostic (1.70e-1)" "potential prognostic unfavorable (7.66e-4)" "unprognostic (2.19e-1)" "unprognostic (3.22e-1)" "unprognostic (1.00e-2)" "unprognostic (1.52e-1)" "unprognostic (8.62e-3)" "unprognostic (2.57e-1)" NRTN NTN ENSG00000171119 Neurturin Q99748 19 5805067-5828324 "Disease related genes, Predicted secreted proteins" "Growth factor" "Disease variant, Hirschsprung disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 18.9;pancreas: 12.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 37.3;Enterocytes: 77.2;Esophageal apical cells: 136.8;Goblet cells: 31.2;Paneth cells: 54.1;Rod photoreceptor cells: 96.5;Salivary acinar cells: 44.9" "Cell type enhanced" "Detected in some" "vascular associated smooth muscle cell: 4.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Testis - Sertoli cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA065260 Approved "Golgi apparatus" "Secreted to blood" "Growth factor" NA NA "Cluster 70: Non-specific - Protein processing" "Cluster 49: Hindbrain - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 2 "Golgi apparatus" "HPA065260: " "unprognostic (5.65e-3)" "unprognostic (8.91e-2)" "unprognostic (1.65e-1)" "unprognostic (1.72e-1)" "unprognostic (7.36e-2)" "unprognostic (1.36e-1)" "unprognostic (1.81e-3)" "unprognostic (1.67e-1)" "potential prognostic favorable (1.00e-4)" "unprognostic (7.93e-2)" "unprognostic (1.45e-3)" "unprognostic (7.86e-3)" "unprognostic (8.88e-2)" "unprognostic (2.86e-1)" "unprognostic (3.02e-3)" "unprognostic (9.86e-2)" "unprognostic (8.95e-2)" "unprognostic (1.45e-2)" "unprognostic (9.80e-2)" "unprognostic (9.11e-3)" "unprognostic (2.94e-1)" "unprognostic (2.11e-1)" "unprognostic (5.84e-3)" "unprognostic (4.48e-1)" "unprognostic (1.27e-1)" "unprognostic (1.59e-1)" NRXN1 "Hs.22998, KIAA0578" ENSG00000179915 "Neurexin 1" "P58400, Q9ULB1" 2 49918503-51225575 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Angiogenesis, Cell adhesion" "Intellectual disability, Schizophrenia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 75.9" "Cell type enhanced" "Detected in many" "Astrocytes: 5666.4;Brain excitatory neurons: 4367.9;Brain inhibitory neurons: 2457.1;Corticotrophs: 4225.1;Ependymal cells: 1563.6;Gonadotrophs: 1381.5;Lactotrophs: 1179.4;Oligodendrocyte progenitor cells: 6784.3;Other brain neurons: 2385.1;Schwann cells: 3656.1;Thyrotrophs: 1451.2" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in some" 8 "Glioblastoma Multiforme (TCGA): 16.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.5" "Lineage enriched" "Detected in single" 12 "granulocytes: 1.5" "Cancer enhanced" "Detected in some" "lung cancer: 4.4;thyroid cancer: 4.6" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Testis - Early spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071400 Approved "Nucleoplasm,Nucleoli,Plasma membrane" "Intracellular and membrane" "Cell adhesion" NA NA 1100000 "Cluster 21: Neutrophils - Unknown function" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 2: Neurons - Nucleosome" "Cluster 65: Non-specific - Unknown function" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 3 "Plasma membrane" "Nucleoplasm, Nucleoli" "HPA071400: " "unprognostic (3.33e-2)" "unprognostic (2.60e-1)" "unprognostic (5.04e-1)" "unprognostic (4.06e-3)" "unprognostic (4.25e-1)" "unprognostic (8.80e-2)" "potential prognostic favorable (3.42e-4)" "unprognostic (8.55e-2)" "unprognostic (7.35e-2)" "unprognostic (1.63e-1)" NRXN2 ENSG00000110076 "Neurexin 2" "P58401, Q9P2S2" 11 64606174-64723197 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 184.5" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 112.4;Brain inhibitory neurons: 81.4;Decidual stromal cells: 45.8;Early primary spermatocytes: 107.7;Late spermatids: 80.8;Leydig cells: 57.9;Müller glia: 48.5;Oligodendrocyte progenitor cells: 121.0;Oligodendrocytes: 50.8;Other brain neurons: 78.3;Peritubular myoid cells: 64.9;Retinal amacrine cells: 219.6;Retinal horizontal cells: 118.2" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 55.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 24.9" "Adipose subcutaneous - Adipose progenitor cells, Lung - Fibroblasts_2, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 2000000 "Cluster 27: Cerebellum - Synaptic function" "Cluster 15: Non-specific - Transcription" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 109: Neurons - Neuronal signaling" "unprognostic (1.70e-1)" "unprognostic (6.83e-2)" "unprognostic (1.52e-3)" "unprognostic (1.52e-2)" "unprognostic (2.42e-1)" "unprognostic (3.96e-1)" "unprognostic (1.73e-1)" "unprognostic (6.02e-3)" "unprognostic (1.07e-2)" "potential prognostic favorable (5.08e-6)" "unprognostic (6.18e-3)" "unprognostic (3.54e-1)" "unprognostic (1.05e-2)" "unprognostic (1.46e-1)" "unprognostic (1.38e-1)" "unprognostic (9.77e-3)" "unprognostic (3.96e-3)" "unprognostic (3.35e-1)" "unprognostic (1.39e-1)" "unprognostic (3.58e-2)" "unprognostic (2.56e-2)" "unprognostic (9.99e-2)" "unprognostic (3.17e-2)" "unprognostic (1.42e-1)" "potential prognostic unfavorable (5.78e-5)" "unprognostic (2.20e-2)" NRXN3 "C14orf60, KIAA0743" ENSG00000021645 "Neurexin 3" "Q9HDB5, Q9Y4C0" 14 78170373-79868291 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 123.6;retina: 39.8" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 3164.4;Brain inhibitory neurons: 5645.6;Oligodendrocytes: 3111.2;Other brain neurons: 2871.5;Retinal amacrine cells: 3686.7;Retinal bipolar cells: 8389.3;Retinal horizontal cells: 3960.7;Schwann cells: 1856.6" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 6 "Kidney Chromophobe (TCGA): 32.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Smooth muscle cells, Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Prostate - Smooth muscle cells, Spleen - Fibroblasts_1, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002727 Approved NA NA 540000 "Cluster 27: Cerebellum - Synaptic function" "Cluster 2: Neurons - Nucleosome" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "HPA002727: " "unprognostic (2.83e-2)" "unprognostic (2.65e-1)" "unprognostic (3.41e-1)" "unprognostic (4.34e-2)" "unprognostic (4.09e-2)" "unprognostic (2.37e-3)" "unprognostic (1.36e-2)" "unprognostic (9.02e-2)" "potential prognostic favorable (2.18e-5)" "unprognostic (1.67e-1)" "unprognostic (8.46e-3)" "unprognostic (4.02e-1)" "unprognostic (1.83e-1)" "unprognostic (2.83e-2)" "unprognostic (1.90e-1)" "unprognostic (1.71e-2)" "unprognostic (7.59e-2)" "unprognostic (5.52e-2)" "unprognostic (3.75e-2)" "unprognostic (3.96e-2)" "unprognostic (1.11e-1)" "unprognostic (5.10e-1)" "unprognostic (7.30e-2)" "unprognostic (2.50e-1)" "unprognostic (2.54e-1)" "unprognostic (4.09e-2)" "unprognostic (1.64e-1)" "unprognostic (4.08e-2)" NSA2 "FLJ94393, HCLG1, HUSSY-29, TINP1" ENSG00000164346 "NSA2 ribosome biogenesis factor" O95478 5 74766991-74780113 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribosome biogenesis, rRNA processing" Ribonucleoprotein "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 611.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" HPA043487 Approved Enhanced Nucleoplasm,Nucleoli No No "Cluster 43: Non-specific - Transcription & Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 55: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 15: Non-specific - Protein processing" 66 "Nucleoplasm, Nucleoli" "HPA043487: " "unprognostic (1.99e-1)" "unprognostic (6.12e-2)" "unprognostic (2.59e-1)" "unprognostic (2.79e-1)" "unprognostic (4.07e-2)" "unprognostic (8.23e-2)" "unprognostic (4.27e-2)" "unprognostic (9.10e-2)" "unprognostic (2.28e-2)" "unprognostic (6.11e-2)" "validated prognostic favorable (1.24e-5)" "validated prognostic favorable (9.18e-4)" "unprognostic (2.92e-1)" "unprognostic (2.44e-2)" "unprognostic (2.04e-3)" "unprognostic (1.82e-1)" "unprognostic (8.07e-2)" "unprognostic (6.30e-2)" "unprognostic (1.51e-2)" "unprognostic (1.22e-1)" "unprognostic (1.79e-1)" "unprognostic (2.30e-1)" "unprognostic (5.79e-2)" "unprognostic (6.11e-2)" "unprognostic (3.35e-1)" "unprognostic (8.75e-2)" "unprognostic (1.11e-2)" "unprognostic (5.32e-2)" "unprognostic (2.35e-1)" "unprognostic (2.56e-1)" "unprognostic (1.83e-1)" NSD1 "ARA267, FLJ22263, KMT3B, STO" ENSG00000165671 "Nuclear receptor binding SET domain protein 1" Q96L73 5 177131830-177300213 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Methyltransferase, Repressor, Transferase" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048431, HPA070333, HPA073705" Supported Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 40: Non-specific - Mixed function" "Cluster 25: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 7: Non-specific - Transcription" 16 Nucleoplasm "Plasma membrane, Cytosol" "HPA048431: , HPA070333: , HPA073705: " "unprognostic (6.67e-2)" "unprognostic (2.42e-2)" "unprognostic (1.34e-2)" "unprognostic (5.42e-3)" "unprognostic (5.02e-2)" "unprognostic (1.17e-1)" "unprognostic (1.79e-1)" "unprognostic (1.61e-1)" "unprognostic (2.45e-1)" "unprognostic (1.72e-3)" "potential prognostic favorable (3.52e-5)" "unprognostic (3.33e-3)" "unprognostic (9.76e-3)" "unprognostic (3.61e-3)" "unprognostic (2.44e-1)" "unprognostic (5.66e-2)" "unprognostic (6.48e-2)" "unprognostic (2.35e-2)" "unprognostic (1.65e-1)" "unprognostic (1.79e-1)" "unprognostic (1.38e-3)" "unprognostic (2.03e-1)" "unprognostic (5.69e-3)" "unprognostic (9.22e-2)" "unprognostic (6.80e-2)" "unprognostic (1.00e-1)" "unprognostic (2.63e-2)" "unprognostic (1.66e-1)" "unprognostic (1.32e-1)" "unprognostic (5.89e-2)" "unprognostic (2.90e-1)" NSD2 "KMT3G, MMSET, WHSC1" ENSG00000109685 "Nuclear receptor binding SET domain protein 2" O96028 4 1871393-1982207 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Disease variant, Intellectual disability, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythrocyte progenitors: 342.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015801, CAB068246, CAB068247" Enhanced Supported Nucleoplasm,Nucleoli No No "Cluster 20: Non-specific - DNA binding" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 27: Non-specific - Cell proliferation" 77 Nucleoplasm Nucleoli "CAB068246: , CAB068247: , HPA015801: " "unprognostic (3.83e-1)" "unprognostic (1.46e-1)" "unprognostic (5.99e-2)" "unprognostic (4.90e-3)" "unprognostic (1.74e-1)" "unprognostic (1.96e-1)" "unprognostic (2.91e-3)" "unprognostic (5.57e-3)" "unprognostic (2.25e-3)" "unprognostic (5.20e-2)" "unprognostic (8.76e-2)" "unprognostic (2.55e-1)" "potential prognostic unfavorable (5.97e-4)" "unprognostic (9.03e-3)" "unprognostic (3.41e-3)" "unprognostic (6.01e-2)" "unprognostic (3.67e-2)" "unprognostic (3.19e-1)" "unprognostic (3.40e-2)" "unprognostic (1.55e-1)" "unprognostic (1.41e-2)" "unprognostic (2.36e-2)" "unprognostic (1.74e-3)" "unprognostic (1.59e-1)" "unprognostic (8.56e-2)" "unprognostic (3.27e-2)" "unprognostic (2.58e-1)" "unprognostic (3.79e-2)" "unprognostic (2.17e-1)" NSD3 "FLJ20353, KMT3F, WHISTLE, WHSC1L1" ENSG00000147548 "Nuclear receptor binding SET domain protein 3" Q9BZ95 8 38269704-38382272 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018893 Supported Approved Nucleoplasm,Mitochondria NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 61: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 38 Mitochondria Nucleoplasm "HPA018893: " "unprognostic (3.50e-2)" "unprognostic (3.42e-2)" "unprognostic (1.32e-1)" "unprognostic (8.45e-3)" "unprognostic (8.67e-3)" "unprognostic (2.77e-1)" "unprognostic (6.99e-3)" "unprognostic (1.83e-2)" "potential prognostic unfavorable (6.58e-4)" "potential prognostic favorable (7.22e-4)" "unprognostic (2.16e-2)" "unprognostic (8.88e-3)" "unprognostic (4.67e-2)" "unprognostic (2.92e-1)" "unprognostic (5.20e-2)" "unprognostic (2.41e-2)" "unprognostic (8.26e-3)" "unprognostic (8.43e-2)" "unprognostic (4.99e-3)" "potential prognostic unfavorable (4.38e-4)" "unprognostic (1.91e-1)" "unprognostic (2.39e-2)" "unprognostic (4.83e-2)" "unprognostic (1.79e-2)" "unprognostic (1.38e-1)" "unprognostic (1.25e-1)" "unprognostic (4.35e-1)" "unprognostic (1.47e-2)" "unprognostic (4.46e-2)" NSDHL "H105e3, SDR31E1, XAP104" ENSG00000147383 "NAD(P) dependent steroid dehydrogenase-like" Q15738 X 152830967-152869729 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Disease variant, Ichthyosis, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 70.7;Epididymal principal cells: 144.0;Esophageal apical cells: 238.6;Esophageal suprabasal cells: 95.0;Oocytes: 147.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Colon - Macrophages, Skin - Sebaceous gland cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000248, HPA000571" Enhanced Enhanced "Endoplasmic reticulum,Lipid droplets" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 37 "Endoplasmic reticulum" "Lipid droplets" "HPA000248: , HPA000571: " "unprognostic (3.04e-2)" "unprognostic (1.61e-2)" "unprognostic (1.68e-1)" "unprognostic (1.67e-1)" "unprognostic (6.50e-2)" "unprognostic (2.62e-1)" "unprognostic (2.21e-1)" "unprognostic (1.96e-1)" "unprognostic (1.00e-2)" "unprognostic (2.71e-3)" "potential prognostic favorable (1.17e-7)" "unprognostic (1.11e-2)" "unprognostic (3.26e-1)" "validated prognostic unfavorable (4.65e-4)" "validated prognostic unfavorable (4.15e-4)" "unprognostic (4.66e-2)" "unprognostic (1.47e-3)" "unprognostic (1.41e-1)" "unprognostic (2.19e-1)" "unprognostic (7.81e-2)" "unprognostic (1.95e-2)" "unprognostic (1.29e-2)" "unprognostic (1.20e-1)" "unprognostic (1.18e-1)" "unprognostic (5.53e-2)" "unprognostic (1.26e-1)" "unprognostic (1.87e-1)" "unprognostic (1.19e-1)" "unprognostic (4.07e-2)" "unprognostic (2.69e-2)" "unprognostic (1.53e-1)" NSF "SEC18, SKD2" ENSG00000073969 "N-ethylmaleimide sensitive factor, vesicle fusing ATPase" P46459 17 46590669-46757679 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" Hydrolase "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 145.0" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 150.3;Brain inhibitory neurons: 184.5;Distal convoluted tubule cells: 142.6;Loop of henle epithelial cells: 123.5;Microglia: 76.0;Oligodendrocyte progenitor cells: 66.9;Other brain neurons: 157.3;Papillary tip epithelial cells: 151.0;Podocytes: 91.4;Proximal tubule cells: 86.0;Renal collecting duct intercalated cells: 109.0;Renal collecting duct principal cells: 147.3;Renal connecting tubule cells: 129.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Macrophages, Pituitary gland - Lactotropes, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003154, CAB009324, HPA071089" Enhanced Supported "Golgi apparatus,Cytosol,Acrosome,Equatorial segment,Mid piece,Principal piece,End piece" NA NA 88000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 102: Non-specific - Mixed function" 102 "Golgi apparatus, Cytosol" "Acrosome, Equatorial segment, Mid piece, Principal piece, End piece" "CAB009324: , HPA003154: , HPA071089: " "unprognostic (2.21e-1)" "unprognostic (8.48e-2)" "unprognostic (3.81e-2)" "unprognostic (9.70e-2)" "potential prognostic favorable (5.87e-4)" "unprognostic (9.23e-2)" "unprognostic (2.33e-1)" "unprognostic (3.47e-2)" "unprognostic (1.15e-2)" "potential prognostic unfavorable (9.71e-4)" "unprognostic (1.05e-3)" "unprognostic (3.52e-1)" "unprognostic (2.03e-1)" "unprognostic (4.28e-2)" "unprognostic (2.90e-1)" "unprognostic (5.76e-2)" "unprognostic (7.97e-2)" "unprognostic (1.18e-1)" "unprognostic (1.32e-1)" "unprognostic (3.72e-2)" "potential prognostic unfavorable (1.07e-4)" "unprognostic (1.12e-1)" "unprognostic (3.90e-2)" "unprognostic (1.06e-1)" "unprognostic (2.66e-2)" "unprognostic (1.61e-1)" "unprognostic (2.08e-2)" "unprognostic (1.60e-1)" "unprognostic (1.13e-1)" "unprognostic (1.13e-1)" "unprognostic (1.13e-1)" NSFL1C "dJ776F14.1, p47, UBX1, UBXD10, UBXN2C" ENSG00000088833 "NSFL1 cofactor" Q9UNZ2 20 1442162-1473842 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 234.1;Oocytes: 271.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skin - Keratinocyte (other), Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047108, HPA050628" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" No No 4300000 "Cluster 22: Eosinophils - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 24: Neutrophils - Innate immunity signal integration" 23 Nucleoplasm "Plasma membrane, Cytosol" "HPA047108: , HPA050628: " "unprognostic (4.31e-2)" "unprognostic (3.98e-2)" "unprognostic (2.03e-1)" "unprognostic (3.64e-2)" "unprognostic (2.65e-1)" "unprognostic (1.80e-3)" "unprognostic (6.44e-2)" "unprognostic (2.90e-1)" "unprognostic (4.33e-2)" "unprognostic (2.21e-1)" "unprognostic (1.15e-3)" "unprognostic (2.50e-1)" "unprognostic (2.92e-2)" "potential prognostic unfavorable (2.26e-4)" "unprognostic (4.04e-3)" "unprognostic (1.76e-2)" "unprognostic (3.60e-2)" "unprognostic (1.31e-2)" "unprognostic (4.69e-2)" "unprognostic (1.18e-1)" "unprognostic (4.05e-2)" "unprognostic (3.12e-1)" "unprognostic (3.43e-2)" "unprognostic (3.19e-2)" "unprognostic (2.06e-1)" "unprognostic (3.47e-1)" "unprognostic (2.39e-1)" "unprognostic (9.19e-2)" "unprognostic (2.79e-1)" "unprognostic (4.05e-2)" "unprognostic (1.70e-1)" NSG1 "D4S234E, NEEP21, P21" ENSG00000168824 "Neuronal vesicle trafficking associated 1" P42857 4 4348140-4419058 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 91.8;pituitary gland: 133.3;skin 1: 105.3" "Cell type enhanced" "Detected in many" "Corticotrophs: 172.9;Cytotrophoblasts: 140.7;Epididymal efferent duct absorptive cells: 200.4;Esophageal basal cells: 124.3;Esophageal suprabasal cells: 159.2;Granulosa cells: 167.9;Melanocytes: 447.4;Oocytes: 538.8;Other brain neurons: 120.8;Retinal bipolar cells: 343.5;Suprabasal keratinocytes: 158.5;Thyrotrophs: 141.1" "Cell type enhanced" "Detected in all" "cerebellar inhibitory: 176.2" "Cancer enriched" "Detected in many" 5 "Skin Cutaneous Melanoma (TCGA): 238.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 41.8;MAIT T-cell: 59.4;memory CD4 T-cell: 38.4;memory CD8 T-cell: 34.8;naive CD8 T-cell: 26.4" "Lineage enriched" "Detected in many" 55 "T-cells: 59.4" "Cancer enhanced" "Detected in many" "Neuroblastoma: 58.3;skin cancer: 48.7" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Breast - Breast myoepithelial cells, Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Minor Salivary Gland - Minor salivary gland basal cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 2: Non-specific - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 32 "unprognostic (7.42e-2)" "unprognostic (4.82e-3)" "unprognostic (7.48e-2)" "unprognostic (4.19e-3)" "unprognostic (9.43e-2)" "unprognostic (1.43e-3)" "unprognostic (5.14e-2)" "unprognostic (2.59e-1)" "unprognostic (5.44e-3)" "unprognostic (2.28e-1)" "unprognostic (2.47e-1)" "unprognostic (2.19e-3)" "unprognostic (7.77e-2)" "unprognostic (1.98e-1)" "unprognostic (7.37e-2)" "unprognostic (1.87e-2)" "unprognostic (1.71e-1)" "unprognostic (2.68e-3)" "unprognostic (1.65e-1)" "unprognostic (3.76e-1)" "unprognostic (2.00e-2)" "unprognostic (3.50e-1)" "unprognostic (2.71e-1)" "unprognostic (2.92e-1)" "unprognostic (1.04e-1)" "unprognostic (2.86e-1)" "unprognostic (1.03e-1)" NSG2 "CALY3, HMP19" ENSG00000170091 "Neuronal vesicle trafficking associated 2" Q9Y328 5 174045706-174243501 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "brain: 442.8" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 95.7;Brain excitatory neurons: 115.4;Brain inhibitory neurons: 264.7;Early spermatids: 77.1;Late primary spermatocytes: 50.4;Late spermatids: 43.1;Oligodendrocyte progenitor cells: 176.3;Other brain neurons: 175.9;Retinal amacrine cells: 253.8;Retinal horizontal cells: 86.1" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in some" 8 "Glioblastoma Multiforme (TCGA): 34.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Neuroblastoma: 170.6;thyroid cancer: 79.3" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pituitary gland - Thyrotropes, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046531, HPA056191" Enhanced Enhanced "Golgi apparatus" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" 8 "Golgi apparatus" "HPA046531: , HPA056191: " "unprognostic (4.83e-2)" "unprognostic (2.24e-1)" "unprognostic (1.14e-3)" "unprognostic (1.01e-1)" "unprognostic (1.86e-1)" "unprognostic (1.44e-2)" "unprognostic (5.17e-1)" NSL1 "C1orf48, DC8, DKFZP566O1646, MIS14" ENSG00000117697 "NSL1 component of MIS12 kinetochore complex" Q96IY1 1 212726153-212791782 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA045761, HPA053721" Enhanced Supported "Nuclear speckles" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" 40 "Nuclear speckles" "HPA045761: , HPA053721: " "unprognostic (2.79e-1)" "unprognostic (2.86e-1)" "unprognostic (1.10e-1)" "unprognostic (1.03e-2)" "unprognostic (5.70e-2)" "unprognostic (2.25e-1)" "unprognostic (7.97e-2)" "potential prognostic favorable (8.60e-4)" "unprognostic (7.24e-2)" "unprognostic (3.26e-3)" "potential prognostic favorable (1.82e-6)" "unprognostic (1.36e-1)" "unprognostic (2.23e-1)" "unprognostic (5.13e-2)" "unprognostic (8.27e-2)" "unprognostic (1.08e-1)" "unprognostic (2.01e-2)" "unprognostic (3.68e-1)" "unprognostic (5.71e-2)" "unprognostic (3.59e-1)" "unprognostic (1.69e-3)" "unprognostic (1.10e-1)" "unprognostic (5.51e-3)" "unprognostic (8.78e-2)" "unprognostic (1.17e-1)" "unprognostic (1.57e-1)" "unprognostic (9.81e-2)" "unprognostic (3.46e-1)" "unprognostic (4.45e-2)" "unprognostic (2.59e-1)" "unprognostic (1.09e-1)" NSMAF "FAN, GRAMD5" ENSG00000035681 "Neutral sphingomyelinase activation associated factor" Q92636 8 58583508-58659853 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 290.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023067, HPA023148, HPA023151" Uncertain Approved Nucleoli NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 49: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 16 Nucleoli "HPA023067: , HPA023148: , HPA023151: " "unprognostic (3.96e-1)" "unprognostic (2.29e-2)" "unprognostic (4.95e-2)" "unprognostic (2.98e-1)" "unprognostic (2.78e-1)" "unprognostic (1.31e-1)" "unprognostic (1.29e-1)" "unprognostic (8.50e-2)" "unprognostic (1.08e-1)" "unprognostic (9.66e-3)" "unprognostic (9.37e-2)" "unprognostic (2.72e-2)" "unprognostic (8.44e-3)" "potential prognostic unfavorable (8.73e-4)" "unprognostic (1.06e-1)" "unprognostic (6.43e-2)" "unprognostic (1.83e-2)" "unprognostic (6.07e-2)" "unprognostic (8.67e-2)" "unprognostic (4.28e-2)" "unprognostic (1.22e-1)" "unprognostic (1.33e-1)" "unprognostic (1.70e-2)" "unprognostic (3.34e-1)" "unprognostic (4.38e-1)" "unprognostic (5.25e-2)" "unprognostic (1.03e-1)" "unprognostic (2.71e-1)" "unprognostic (3.79e-1)" "unprognostic (1.13e-1)" "unprognostic (1.40e-1)" NSMCE1 NSE1 ENSG00000169189 "NSE1 homolog, SMC5-SMC6 complex component" Q8WV22 16 27224994-27268772 "Enzymes, Essential proteins, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 275.2;Late spermatids: 585.7;Mast cells: 240.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041567, HPA043091" Supported Supported Nucleoplasm,Vesicles NA NA "Cluster 41: Basophils - Unknown function" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 21: Non-specific - Metabolism" "Cluster 35: RS4;11 - Unknown function" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 32 Nucleoplasm Vesicles "HPA041567: , HPA043091: " "unprognostic (3.40e-1)" "unprognostic (4.56e-2)" "unprognostic (1.67e-1)" "unprognostic (1.07e-1)" "unprognostic (9.02e-2)" "unprognostic (8.94e-2)" "unprognostic (6.10e-2)" "unprognostic (3.38e-3)" "potential prognostic unfavorable (7.29e-4)" "unprognostic (2.26e-1)" "unprognostic (1.14e-2)" "unprognostic (3.40e-1)" "unprognostic (3.05e-2)" "unprognostic (5.57e-3)" "unprognostic (5.24e-2)" "unprognostic (1.53e-3)" "unprognostic (5.82e-3)" "unprognostic (9.37e-2)" "unprognostic (1.09e-1)" "unprognostic (1.46e-1)" "unprognostic (3.36e-2)" "unprognostic (8.39e-2)" "unprognostic (1.71e-1)" "unprognostic (7.52e-2)" "unprognostic (3.06e-2)" "unprognostic (3.27e-2)" "unprognostic (2.95e-2)" "unprognostic (3.97e-3)" "unprognostic (1.23e-1)" "unprognostic (1.99e-1)" "unprognostic (1.09e-1)" NSMCE2 "C8orf36, FLJ32440, MMS21, NSE2, ZMIZ7" ENSG00000156831 "NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase" Q96MF7 8 125091679-125367120 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA recombination, DNA repair, Mitosis, Ubl conjugation pathway" Transferase "Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 833.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051614, HPA065734" Supported Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 18 Nucleoplasm "Nuclear bodies" "HPA051614: , HPA065734: " "unprognostic (9.09e-2)" "potential prognostic unfavorable (3.87e-4)" "unprognostic (2.03e-2)" "unprognostic (3.79e-1)" "unprognostic (2.10e-1)" "unprognostic (5.06e-3)" "unprognostic (1.10e-1)" "unprognostic (8.09e-3)" "unprognostic (1.77e-2)" "unprognostic (6.58e-2)" "potential prognostic favorable (2.58e-7)" "unprognostic (6.44e-2)" "unprognostic (4.09e-3)" "potential prognostic unfavorable (8.49e-4)" "unprognostic (1.60e-3)" "unprognostic (2.38e-3)" "unprognostic (1.51e-1)" "unprognostic (2.62e-1)" "unprognostic (4.52e-2)" "unprognostic (2.35e-1)" "unprognostic (1.04e-2)" "validated prognostic unfavorable (7.53e-4)" "validated prognostic unfavorable (3.86e-5)" "unprognostic (3.78e-2)" "unprognostic (1.68e-1)" "unprognostic (1.02e-1)" "unprognostic (6.98e-2)" "unprognostic (9.15e-2)" "unprognostic (2.65e-1)" "unprognostic (1.70e-1)" "unprognostic (4.07e-2)" NSMCE3 "HCA4, MAGEG1, MAGEL3, NDNL2, NSE3" ENSG00000185115 "NSE3 homolog, SMC5-SMC6 complex component" Q96MG7 15 29264989-29269822 "Disease related genes, Essential proteins, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Growth regulation, Ubl conjugation pathway" "Tumor antigen" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" NA NA "Cluster 68: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 70: DU4475 - Unknown function" 33 "unprognostic (3.27e-1)" "unprognostic (1.43e-1)" "unprognostic (1.36e-1)" NSMCE4A "bA500G22.3, C10orf86, FLJ20003, NSE4A" ENSG00000107672 "NSE4 homolog A, SMC5-SMC6 complex component" Q9NXX6 10 121957091-121975217 "Essential proteins, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037459, HPA038412, HPA044872" Approved Enhanced Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 77: Intestine - Digestion" "Cluster 11: White matter - Signal transduction" "Cluster 52: Non-specific - Mitochondria" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 15 Nucleoplasm "HPA037459: , HPA038412: , HPA044872: " "unprognostic (1.50e-1)" "unprognostic (1.50e-1)" "unprognostic (9.54e-2)" "potential prognostic favorable (8.53e-4)" "unprognostic (8.55e-2)" "unprognostic (6.21e-2)" "unprognostic (5.58e-2)" "potential prognostic favorable (4.51e-4)" "unprognostic (1.87e-1)" "unprognostic (1.10e-1)" "unprognostic (3.38e-3)" "unprognostic (1.03e-1)" "unprognostic (1.70e-1)" "unprognostic (2.08e-2)" "unprognostic (1.68e-3)" "unprognostic (6.23e-2)" "unprognostic (7.44e-2)" "unprognostic (3.56e-2)" "unprognostic (6.49e-2)" "unprognostic (1.57e-1)" "unprognostic (4.12e-2)" "unprognostic (4.12e-1)" "unprognostic (3.42e-1)" "unprognostic (2.09e-2)" "unprognostic (9.81e-2)" "unprognostic (6.97e-2)" "unprognostic (2.11e-1)" "unprognostic (8.50e-2)" "unprognostic (8.22e-2)" "unprognostic (5.74e-2)" "unprognostic (1.95e-1)" NSMF NELF ENSG00000165802 "NMDA receptor synaptonuclear signaling and neuronal migration factor" Q6X4W1 9 137447570-137459334 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "brain: 654.1" "Cell type enhanced" "Detected in many" "Astrocytes: 119.6;Bergmann glia: 77.0;Choroid plexus epithelial cells: 66.0;Ependymal cells: 192.3;Epididymal efferent duct ciliated cells: 76.4;Peritubular myoid cells: 83.6;Proximal tubule cells: 78.7" "Cell type enhanced" "Detected in all" "ependymal cell: 262.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "eosinophil: 3.6;intermediate monocyte: 13.8;myeloid DC: 6.3;non-classical monocyte: 12.1" "Group enriched" "Detected in many" 5 "dendritic cells: 6.3;granulocytes: 3.6;monocytes: 13.8" "Low cancer specificity" "Detected in all" "Pituitary gland - Corticotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044316 Supported Supported Nucleoplasm NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 34: Ciliated cells - Cilia assembly & function" 1 Nucleoplasm "HPA044316: " "unprognostic (4.08e-2)" "unprognostic (5.42e-3)" "unprognostic (7.52e-3)" "potential prognostic unfavorable (2.19e-4)" "unprognostic (2.91e-1)" "unprognostic (5.58e-1)" "unprognostic (6.41e-2)" "unprognostic (1.28e-2)" "unprognostic (2.42e-2)" "potential prognostic favorable (2.65e-5)" "unprognostic (4.45e-2)" "unprognostic (2.28e-2)" "unprognostic (9.54e-3)" "unprognostic (8.64e-2)" "unprognostic (1.45e-1)" "unprognostic (2.65e-1)" "unprognostic (4.11e-3)" "unprognostic (8.30e-2)" "unprognostic (3.56e-1)" "unprognostic (7.21e-2)" "unprognostic (2.37e-2)" "unprognostic (1.07e-3)" "unprognostic (1.80e-1)" "unprognostic (1.75e-1)" "unprognostic (1.44e-1)" "unprognostic (3.20e-2)" "unprognostic (1.16e-1)" "unprognostic (1.83e-1)" "unprognostic (5.62e-2)" NSRP1 "CCDC55, DKFZP434K1421, NSrp70" ENSG00000126653 "Nuclear speckle splicing regulatory protein 1" Q9H0G5 17 30115521-30186475 "Disease related genes, Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015593, HPA015603" Enhanced Supported Nucleoplasm NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 6: Non-specific - Immune response" "Cluster 27: Breast cancer - Unknown function" "Cluster 17: Non-specific - RNA processing" 31 Nucleoplasm "HPA015593: , HPA015603: " "unprognostic (1.58e-1)" "unprognostic (3.80e-2)" "unprognostic (2.19e-1)" "unprognostic (3.39e-1)" "unprognostic (8.38e-2)" "unprognostic (2.12e-1)" "unprognostic (9.46e-2)" "unprognostic (9.22e-2)" "unprognostic (2.45e-3)" "unprognostic (8.18e-3)" "unprognostic (5.35e-3)" "unprognostic (1.31e-1)" "unprognostic (8.41e-2)" "unprognostic (3.89e-3)" "unprognostic (7.84e-3)" "unprognostic (1.11e-1)" "unprognostic (1.92e-1)" "unprognostic (2.43e-2)" "unprognostic (3.42e-1)" "unprognostic (3.28e-1)" "unprognostic (7.07e-2)" "unprognostic (6.40e-3)" "unprognostic (1.26e-1)" "unprognostic (1.98e-3)" "unprognostic (1.19e-3)" "unprognostic (1.44e-3)" "unprognostic (2.00e-1)" "unprognostic (3.47e-1)" "unprognostic (6.03e-2)" "unprognostic (2.45e-1)" NSUN2 "FLJ20303, Misu, MRT5, SAKI, TRM4" ENSG00000037474 "NOP2/Sun RNA methyltransferase 2" Q08J23 5 6599239-6633291 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Mitosis, Spermatogenesis, tRNA processing" "Methyltransferase, RNA-binding, Transferase, tRNA-binding" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037896 Supported Uncertain Nucleoplasm "Intracellular and membrane" Enzyme NA NA 54000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 29: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 41 Nucleoplasm "HPA037896: " "unprognostic (2.36e-3)" "unprognostic (5.55e-3)" "unprognostic (2.52e-1)" "unprognostic (2.02e-3)" "unprognostic (1.63e-2)" "unprognostic (1.74e-1)" "unprognostic (2.76e-1)" "unprognostic (8.67e-2)" "unprognostic (7.58e-2)" "unprognostic (1.32e-2)" "unprognostic (1.53e-3)" "unprognostic (2.20e-1)" "unprognostic (1.23e-1)" "unprognostic (1.84e-2)" "unprognostic (7.58e-3)" "unprognostic (2.92e-3)" "potential prognostic unfavorable (3.34e-5)" "unprognostic (2.12e-1)" "unprognostic (1.25e-1)" "unprognostic (2.42e-1)" "unprognostic (1.09e-2)" "unprognostic (5.65e-3)" "unprognostic (1.07e-3)" "unprognostic (4.48e-2)" "unprognostic (1.57e-1)" "unprognostic (1.90e-1)" "unprognostic (8.59e-2)" "unprognostic (8.98e-2)" "unprognostic (2.19e-1)" "unprognostic (6.92e-2)" "unprognostic (9.51e-2)" NSUN3 FLJ22609 ENSG00000178694 "NOP2/Sun RNA methyltransferase 3" Q9H649 3 94062980-94131832 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Methyltransferase, RNA-binding, Transferase, tRNA-binding" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 132.9;Sertoli cells: 142.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036181 Uncertain NA NA "Cluster 41: Basophils - Unknown function" "Cluster 42: Retina - Visual perception" "Cluster 9: Non-specific - Receptor signaling" "Cluster 7: Liver cancer - Metabolism" "Cluster 7: Non-specific - Transcription" 4 "HPA036181: " "unprognostic (2.40e-2)" "unprognostic (3.03e-3)" "unprognostic (3.39e-1)" "unprognostic (2.40e-1)" "unprognostic (3.61e-1)" "unprognostic (2.14e-1)" "unprognostic (1.29e-1)" "unprognostic (5.86e-3)" "unprognostic (1.57e-1)" "unprognostic (2.94e-3)" "unprognostic (3.83e-3)" "unprognostic (2.69e-1)" "unprognostic (1.73e-1)" "unprognostic (1.11e-3)" "unprognostic (2.50e-1)" "unprognostic (2.31e-1)" "unprognostic (1.43e-1)" "unprognostic (2.69e-1)" "unprognostic (4.27e-3)" "unprognostic (8.13e-2)" "unprognostic (4.11e-3)" "unprognostic (2.39e-2)" "unprognostic (1.74e-1)" "unprognostic (2.62e-2)" "unprognostic (1.49e-2)" "unprognostic (1.26e-1)" "unprognostic (5.52e-2)" "unprognostic (2.15e-1)" "unprognostic (3.07e-1)" "unprognostic (2.82e-1)" "unprognostic (6.01e-2)" NSUN4 "MGC22960, SHTAP" ENSG00000117481 "NOP2/Sun RNA methyltransferase 4" Q96CB9 1 46340789-46365152 "Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Methyltransferase, RNA-binding, rRNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 10 "testis: 80.0" "Cell type enriched" "Detected in all" 5 "Late spermatids: 922.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" HPA028489 Approved NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 6: Testis - Spermatogenesis" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 23 "HPA028489: " "unprognostic (2.54e-2)" "unprognostic (1.50e-1)" "unprognostic (6.78e-3)" "unprognostic (3.24e-1)" "unprognostic (5.83e-2)" "unprognostic (2.99e-1)" "unprognostic (1.18e-1)" "unprognostic (2.32e-1)" "unprognostic (2.49e-1)" "unprognostic (3.07e-1)" "unprognostic (1.49e-3)" "unprognostic (2.66e-1)" "unprognostic (2.64e-2)" "potential prognostic unfavorable (1.58e-4)" "unprognostic (3.38e-3)" "unprognostic (3.86e-2)" "unprognostic (2.29e-2)" "unprognostic (4.11e-1)" "unprognostic (1.94e-1)" "unprognostic (1.55e-1)" "unprognostic (3.99e-2)" "unprognostic (2.05e-1)" "unprognostic (1.01e-1)" "unprognostic (2.14e-1)" "unprognostic (2.90e-2)" "unprognostic (6.30e-2)" "unprognostic (1.86e-3)" "unprognostic (2.39e-1)" "unprognostic (5.35e-2)" "unprognostic (1.50e-2)" "unprognostic (1.23e-1)" NSUN5 "FLJ10267, NOL1R, NSUN5A, p120(NOL1), WBSCR20, WBSCR20A, Ynl022cL" ENSG00000130305 "NOP2/Sun RNA methyltransferase 5" Q96P11 7 73302516-73308826 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "rRNA processing" "Methyltransferase, RNA-binding, Transferase" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 60.2;Neutrophil progenitors: 109.7;Oocytes: 138.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020536, HPA045590, HPA046867" Approved Enhanced Nucleoplasm,Nucleoli NA NA "Cluster 32: Basophils - Transcription" "Cluster 24: Non-specific - Transcription" "Cluster 30: White matter - Myelination" "Cluster 39: Non-specific - Transcription" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 4 "Nucleoplasm, Nucleoli" "HPA020536: , HPA045590: , HPA046867: " "unprognostic (9.60e-3)" "unprognostic (6.87e-2)" "unprognostic (1.49e-1)" "unprognostic (1.26e-1)" "unprognostic (1.65e-1)" "unprognostic (1.71e-1)" "potential prognostic unfavorable (1.49e-4)" "unprognostic (1.91e-3)" "unprognostic (2.61e-1)" "unprognostic (1.11e-1)" "unprognostic (2.77e-3)" "unprognostic (1.72e-2)" "unprognostic (9.09e-2)" "potential prognostic unfavorable (1.81e-7)" "unprognostic (8.65e-3)" "unprognostic (5.48e-2)" "unprognostic (8.51e-2)" "unprognostic (2.37e-1)" "unprognostic (5.00e-1)" "unprognostic (3.79e-2)" "unprognostic (6.31e-3)" "unprognostic (9.05e-2)" "unprognostic (3.04e-1)" "unprognostic (1.77e-1)" "unprognostic (2.79e-1)" "unprognostic (1.46e-1)" "unprognostic (1.50e-2)" "unprognostic (1.36e-1)" "unprognostic (3.42e-1)" "unprognostic (2.88e-1)" "unprognostic (1.22e-1)" NSUN6 "ARL5B-AS1, FLJ23743, NOPD1" ENSG00000241058 "NOP2/Sun RNA methyltransferase 6" Q8TEA1 10 18545561-18659285 "Predicted intracellular proteins" "Methyltransferase, RNA-binding, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 57.1" "Cell type enhanced" "Detected in all" "Hepatocytes: 366.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045902 Approved Approved "Golgi apparatus" NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 53: Neurons - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "Golgi apparatus" "HPA045902: " "unprognostic (6.63e-2)" "unprognostic (1.34e-1)" "unprognostic (2.93e-2)" "unprognostic (7.42e-2)" "potential prognostic unfavorable (5.13e-4)" "unprognostic (4.48e-2)" "unprognostic (9.71e-2)" "potential prognostic favorable (7.36e-6)" "unprognostic (4.16e-2)" "unprognostic (1.59e-1)" "unprognostic (4.94e-3)" "unprognostic (8.51e-2)" "unprognostic (1.79e-2)" "unprognostic (7.15e-2)" "potential prognostic favorable (6.38e-6)" "unprognostic (1.48e-1)" "unprognostic (1.20e-1)" "unprognostic (1.22e-2)" "unprognostic (1.73e-2)" "unprognostic (1.75e-1)" "unprognostic (1.93e-1)" "unprognostic (1.16e-2)" "unprognostic (8.96e-3)" "unprognostic (3.35e-1)" "unprognostic (2.60e-2)" "unprognostic (3.04e-1)" "unprognostic (1.25e-1)" "unprognostic (7.73e-2)" "unprognostic (4.01e-2)" "unprognostic (1.24e-2)" "unprognostic (8.43e-2)" NSUN7 FLJ14001 ENSG00000179299 "NOP2/Sun RNA methyltransferase family member 7" Q8NE18 4 40749925-40811184 "Predicted intracellular proteins" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 15.4" "Cell type enhanced" "Detected in many" "Ependymal cells: 131.5;Fallopian tube ciliated cells: 137.1;Late spermatids: 163.6;Neutrophils: 275.2;Respiratory ciliated cells: 366.2" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 93.0;ependymal cell: 140.6" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 13.6" "Region enhanced" "Detected in all" "choroid plexus: 15.6" "Immune cell enriched" "Detected in single" 6 "neutrophil: 2.7" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.7" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Spleen - Neutrophils_2, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA020653 Uncertain Approved Vesicles NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 24: Neutrophils - Innate immunity signal integration" Vesicles "HPA020653: " "unprognostic (7.77e-3)" "unprognostic (1.37e-1)" "unprognostic (3.39e-1)" "unprognostic (1.20e-2)" "unprognostic (2.46e-2)" "unprognostic (2.19e-1)" "unprognostic (3.50e-2)" "potential prognostic unfavorable (5.56e-6)" "unprognostic (7.12e-2)" "potential prognostic favorable (1.44e-5)" "unprognostic (2.11e-3)" "potential prognostic favorable (3.31e-4)" "unprognostic (3.24e-2)" "unprognostic (3.10e-1)" "unprognostic (1.10e-1)" "unprognostic (1.19e-1)" "unprognostic (7.39e-2)" "unprognostic (4.53e-3)" "unprognostic (3.15e-1)" "unprognostic (1.12e-1)" "unprognostic (6.09e-2)" "unprognostic (6.24e-3)" "unprognostic (8.76e-3)" "unprognostic (1.81e-1)" "unprognostic (1.36e-1)" "unprognostic (1.68e-1)" "unprognostic (3.47e-1)" NT5C "cdN, DNT-1, DNT1, PN-I, UMPH2" ENSG00000125458 "5', 3'-nucleotidase, cytosolic" Q8TCD5 17 75130225-75131757 "Metabolic proteins, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 218.2;Enterocytes: 199.8;Esophageal basal cells: 203.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021581, HPA023632" Approved Supported Cytosol NA NA 300000 "Cluster 32: Basophils - Transcription" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 15 Cytosol "HPA021581: , HPA023632: " "unprognostic (5.69e-2)" "unprognostic (1.47e-1)" "unprognostic (3.98e-3)" "unprognostic (1.02e-1)" "unprognostic (8.37e-3)" "unprognostic (2.33e-1)" "unprognostic (1.17e-2)" "unprognostic (4.36e-2)" "unprognostic (2.61e-1)" "unprognostic (3.27e-2)" "unprognostic (3.42e-2)" "unprognostic (2.98e-2)" "unprognostic (3.21e-3)" "potential prognostic unfavorable (5.31e-5)" "unprognostic (2.90e-3)" "unprognostic (3.25e-2)" "unprognostic (2.65e-1)" "unprognostic (9.80e-2)" "unprognostic (7.48e-2)" "unprognostic (2.36e-1)" "potential prognostic favorable (5.08e-4)" "unprognostic (3.78e-1)" "unprognostic (2.37e-2)" "unprognostic (1.55e-1)" "unprognostic (2.15e-1)" "unprognostic (5.72e-2)" "unprognostic (1.88e-1)" "unprognostic (1.57e-1)" "unprognostic (4.29e-1)" "unprognostic (2.36e-1)" "unprognostic (9.09e-2)" NT5C1A "CN-I, CN-IA, CN1, CN1A, MGC119199, MGC119201" ENSG00000116981 "5'-nucleotidase, cytosolic IA" Q9BXI3 1 39651229-39672107 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "skeletal muscle: 72.5;tongue: 29.1" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 31.9;Cardiomyocytes: 12.7;Hepatic stellate cells: 6.5;Myonuclei: 27.1;Oocytes: 4.6;Peritubular myoid cells: 4.3;Retinal amacrine cells: 8.1;Thymic myoid cells: 4.1;Vascular smooth muscle cells: 5.0" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 8 "Neuroblastoma: 3.3" "Adrenal gland - Adrenal medulla cells, Heart muscle - Cardiomyocytes, Prostate - Fibroblasts, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050283, HPA054158" Supported NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 2: Neurons - Nucleosome" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 15 "HPA050283: , HPA054158: " "unprognostic (4.16e-3)" NT5C1B "AIRP, CN-IB" ENSG00000185013 "5'-nucleotidase, cytosolic IB" Q96P26 2 18562871-18589572 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 32 "testis: 33.8" "Group enriched" "Detected in some" 5 "Early spermatids: 4.2;Late spermatids: 14.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in single" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA056683 Uncertain Approved "Nucleoplasm,Nucleoli,Plasma membrane,Connecting piece,Mid piece" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 6: Testis - Spermatogenesis" "Cluster 3: Choroid plexus - Cilium" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" "Nucleoli, Plasma membrane" "Nucleoplasm, Connecting piece, Mid piece" "HPA056683: " "unprognostic (4.55e-2)" "unprognostic (5.35e-2)" "unprognostic (1.33e-1)" "unprognostic (5.81e-2)" "unprognostic (1.80e-2)" "unprognostic (2.51e-1)" NT5C1B-RDH14 ENSG00000250741 "NT5C1B-RDH14 readthrough" 2 18555545-18589564 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 125 "testis: 15.4" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 108.1;Early spermatids: 77.0;Epicardial cells: 77.3;Late spermatids: 99.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA056683 Uncertain Approved "Nucleoplasm,Nucleoli,Plasma membrane,Connecting piece,Mid piece" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" "Nucleoplasm, Plasma membrane" "Nucleoli, Connecting piece, Mid piece" "HPA056683: " NT5C2 "cN-II, GMP, NT5B, PNT5, SPG45, SPG65" ENSG00000076685 "5'-nucleotidase, cytosolic II" P49902 10 103087185-103277605 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotide metabolism" "Allosteric enzyme, Hydrolase, Transferase" "Cancer-related genes, Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 875.3;Myonuclei: 1164.1;Neutrophil progenitors: 1125.7;Neutrophils: 1492.0;Urothelial cells: 1050.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003751 Approved NA NA 8000 "Cluster 28: Neutrophils - Unknown function" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 21: Non-specific - Metabolism" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 24: Neutrophils - Innate immunity signal integration" 20 "HPA003751: " "unprognostic (2.61e-3)" "unprognostic (9.73e-2)" "unprognostic (1.32e-2)" "unprognostic (2.02e-1)" "unprognostic (2.20e-1)" "unprognostic (2.14e-1)" "unprognostic (2.84e-1)" "unprognostic (2.59e-3)" "unprognostic (1.44e-1)" "unprognostic (1.82e-1)" "unprognostic (1.11e-2)" "unprognostic (8.31e-3)" "unprognostic (1.15e-1)" "potential prognostic unfavorable (7.91e-5)" "unprognostic (6.65e-2)" "unprognostic (5.72e-3)" "unprognostic (4.24e-2)" "unprognostic (3.02e-1)" "unprognostic (1.99e-1)" "unprognostic (4.28e-1)" "unprognostic (8.07e-2)" "unprognostic (2.16e-2)" "unprognostic (1.86e-2)" "unprognostic (1.55e-1)" "unprognostic (1.43e-1)" "unprognostic (3.85e-2)" "unprognostic (7.98e-2)" "unprognostic (7.01e-2)" "unprognostic (4.82e-2)" "unprognostic (1.53e-1)" "unprognostic (5.07e-2)" NT5C3A "cN-III, hUMP1, NT5C3, p36, P5'N-1, PN-I, POMP, PSN1, UMPH, UMPH1" ENSG00000122643 "5'-nucleotidase, cytosolic IIIA" Q9H0P0 7 33014130-33062796 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotide metabolism" "Hydrolase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 82.6" "Cell type enriched" "Detected in all" 4 "Platelets: 1661.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010520, HPA010630, HPA029058" Uncertain Supported "Nucleoplasm,Nuclear bodies,Endoplasmic reticulum,Cytosol" NA NA 23000 "Cluster 20: Non-specific - DNA binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 47: Platelets - Hemostasis" 5 "Endoplasmic reticulum, Cytosol" "Nucleoplasm, Nuclear bodies" "HPA010520: , HPA010630: , HPA029058: " "unprognostic (2.59e-2)" "unprognostic (4.07e-2)" "unprognostic (4.39e-3)" "unprognostic (7.33e-2)" "unprognostic (9.81e-2)" "unprognostic (2.57e-1)" "unprognostic (1.31e-2)" "unprognostic (7.15e-2)" "unprognostic (1.89e-2)" "unprognostic (3.13e-1)" "unprognostic (8.44e-2)" "unprognostic (2.06e-2)" "potential prognostic unfavorable (3.96e-4)" "potential prognostic unfavorable (5.59e-4)" "unprognostic (9.28e-3)" "unprognostic (2.22e-1)" "unprognostic (1.75e-1)" "unprognostic (3.62e-2)" "unprognostic (9.62e-2)" "unprognostic (1.40e-3)" "unprognostic (7.42e-2)" "unprognostic (5.09e-2)" "unprognostic (1.55e-1)" "unprognostic (1.58e-1)" "unprognostic (4.62e-3)" "unprognostic (3.14e-1)" "unprognostic (2.74e-1)" "unprognostic (5.52e-3)" "unprognostic (4.50e-2)" NT5C3B "cN-IIIB, MGC20781, NT5C3L" ENSG00000141698 "5'-nucleotidase, cytosolic IIIB" Q969T7 17 41825057-41836260 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 202.7;Late spermatids: 163.2;Retinal horizontal cells: 100.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030786, HPA057095" Approved NA NA "Cluster 18: Non-specific - Translation" "Cluster 70: Non-specific - Protein processing" "Cluster 15: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 62: Smooth muscle cells - Muscle contraction" 1 "HPA030786: , HPA057095: " "unprognostic (1.75e-1)" "unprognostic (8.22e-2)" "unprognostic (1.76e-1)" "unprognostic (3.53e-2)" "unprognostic (1.96e-2)" "unprognostic (3.11e-3)" "unprognostic (1.31e-2)" "unprognostic (5.93e-3)" "potential prognostic unfavorable (7.71e-5)" "unprognostic (1.46e-1)" "unprognostic (4.08e-2)" "unprognostic (2.92e-1)" "potential prognostic unfavorable (3.61e-6)" "unprognostic (2.73e-1)" "unprognostic (1.59e-1)" "unprognostic (2.79e-1)" "unprognostic (8.10e-2)" "unprognostic (1.48e-1)" "unprognostic (3.15e-1)" "potential prognostic favorable (9.20e-4)" "unprognostic (2.05e-2)" "unprognostic (1.87e-1)" "unprognostic (1.30e-3)" "unprognostic (5.05e-2)" "unprognostic (3.34e-3)" "unprognostic (5.11e-3)" "unprognostic (5.07e-2)" "unprognostic (1.56e-1)" "unprognostic (2.84e-3)" NT5DC1 "dJ486I3.1, MGC24302, NT5C2L1" ENSG00000178425 "5'-nucleotidase domain containing 1" Q5TFE4 6 116100851-116249497 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 130.5" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 1726.7;Oligodendrocytes: 443.7" "Group enriched" "Detected in all" 4 "choroid plexus epithelial cell: 1621.6;oligodendrocyte: 685.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030352, HPA079264" Uncertain Approved Nucleoplasm,Cytosol NA NA 150000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 21: Non-specific - Metabolism" "Cluster 55: Lymphoma - Immune response" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 1 Nucleoplasm Cytosol "HPA030352: , HPA079264: " "unprognostic (2.55e-1)" "unprognostic (1.02e-1)" "unprognostic (2.68e-1)" "unprognostic (9.40e-2)" "unprognostic (1.20e-2)" "unprognostic (9.88e-2)" "unprognostic (1.43e-1)" "unprognostic (1.05e-1)" "unprognostic (1.47e-1)" "unprognostic (6.09e-2)" "potential prognostic favorable (9.44e-11)" "unprognostic (1.22e-2)" "unprognostic (1.42e-1)" "unprognostic (1.31e-1)" "unprognostic (1.06e-1)" "unprognostic (3.04e-1)" "unprognostic (5.72e-2)" "unprognostic (2.37e-1)" "unprognostic (1.62e-1)" "unprognostic (3.70e-3)" "unprognostic (8.05e-2)" "unprognostic (1.30e-1)" "unprognostic (5.08e-2)" "unprognostic (8.73e-2)" "unprognostic (4.86e-3)" "unprognostic (1.38e-2)" "unprognostic (1.14e-1)" "unprognostic (5.37e-2)" "unprognostic (1.72e-1)" "unprognostic (1.10e-1)" "unprognostic (1.36e-1)" NT5DC2 FLJ12442 ENSG00000168268 "5'-nucleotidase domain containing 2" Q9H857 3 52524385-52535054 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 74.5;Hepatic stellate cells: 77.5;Pericytes: 72.5;Peritubular myoid cells: 137.1;Plasma cells: 64.4;Vascular smooth muscle cells: 93.2" "Cell type enhanced" "Detected in many" "ependymal cell: 45.8;pericyte: 86.4;vascular associated smooth muscle cell: 36.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050683 Approved NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 35: Non-specific - Mixed function" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 110: Mural cells - ECM organization" 6 "HPA050683: " "unprognostic (4.93e-2)" "unprognostic (1.92e-2)" "unprognostic (1.56e-1)" "unprognostic (3.12e-2)" "unprognostic (1.19e-1)" "unprognostic (3.68e-2)" "unprognostic (6.44e-2)" "unprognostic (3.16e-1)" "unprognostic (2.66e-1)" "unprognostic (7.34e-3)" "unprognostic (1.37e-1)" "unprognostic (2.18e-1)" "unprognostic (7.11e-3)" "potential prognostic unfavorable (3.88e-5)" "unprognostic (3.81e-3)" "unprognostic (2.04e-2)" "unprognostic (7.93e-3)" "unprognostic (2.78e-1)" "unprognostic (4.36e-1)" "unprognostic (7.33e-2)" "unprognostic (2.07e-1)" "unprognostic (1.84e-1)" "unprognostic (7.58e-3)" "unprognostic (4.75e-1)" "unprognostic (1.82e-1)" "unprognostic (2.52e-1)" "unprognostic (1.74e-1)" "unprognostic (1.28e-1)" "unprognostic (1.51e-1)" "unprognostic (3.27e-1)" "unprognostic (1.20e-1)" NT5DC3 "FLJ11266, TU12B1-TY" ENSG00000111696 "5'-nucleotidase domain containing 3" Q86UY8 12 103770453-103841234 "Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 74.2" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 122.0;Neutrophil progenitors: 160.5;Salivary acinar cells: 135.6;Salivary basal cells: 163.0;Salivary myoepithelial cells: 119.2;Smooth muscle cells: 130.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041634 Approved Mitochondria,Cytosol NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 51: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 2 Mitochondria Cytosol "HPA041634: " "unprognostic (2.44e-1)" "unprognostic (1.48e-1)" "unprognostic (1.41e-1)" "unprognostic (9.76e-2)" "unprognostic (1.52e-1)" "unprognostic (7.51e-2)" "unprognostic (8.72e-2)" "unprognostic (6.80e-2)" "unprognostic (1.59e-1)" "potential prognostic unfavorable (2.43e-4)" "unprognostic (1.68e-1)" "unprognostic (2.54e-2)" "unprognostic (5.25e-3)" "validated prognostic unfavorable (7.99e-6)" "validated prognostic unfavorable (3.04e-5)" "unprognostic (2.12e-2)" "unprognostic (1.01e-3)" "unprognostic (6.44e-2)" "potential prognostic favorable (2.81e-4)" "unprognostic (4.53e-3)" "unprognostic (9.25e-2)" "unprognostic (8.16e-2)" "unprognostic (2.82e-1)" "unprognostic (3.07e-1)" "unprognostic (1.54e-1)" "unprognostic (9.38e-2)" "unprognostic (2.19e-1)" "unprognostic (2.27e-2)" "unprognostic (3.35e-2)" "unprognostic (7.70e-2)" "unprognostic (1.94e-2)" NT5DC4 ENSG00000144130 "5'-nucleotidase domain containing 4" Q86YG4 2 112721020-112742879 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 1.1;testis: 2.4" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 2.9;Early spermatids: 35.8;Endometrial glandular cells: 4.6;Endometrial luminal cells: 11.8;Late spermatids: 9.1;Sertoli cells: 5.6;Urothelial cells: 3.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose visceral - Neutrophils, Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" HPA046856 Uncertain NA NA "Cluster 39: Testis - Nuclear processes" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" "HPA046856: " NT5E "CALJA, CD73, eN, eNT, NT5" ENSG00000135318 "5'-nucleotidase ecto" P21589 6 85449584-85495791 "CD markers, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 105.8" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 74.5;Corticotrophs: 175.9;Endometrial glandular cells: 116.3;Lymphatic endothelial cells: 78.6;Oligodendrocyte progenitor cells: 89.3;Pituicytes/FSCs: 118.2;Podocytes: 70.5;Respiratory deuterosomal cells: 79.8;Rod photoreceptor cells: 284.0" "Group enriched" "Detected in many" 4 "astrocyte: 61.5;committed oligodendrocyte precursor: 49.2;fibroblast: 112.0;oligodendrocyte precursor cell: 93.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 33.1;naive CD8 T-cell: 30.8" "Group enriched" "Detected in many" 41 "B-cells: 33.1;T-cells: 30.8" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 320.3" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Lung - Fibroblasts_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017357 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" Enzyme NA NA 960000 "Cluster 34: B-cells - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 44: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 79: Photoreceptor cells - Phototransduction" 7 "Plasma membrane" "Nucleoplasm, Cytosol" "HPA017357: " "unprognostic (7.12e-3)" "unprognostic (1.13e-1)" "unprognostic (9.12e-2)" "unprognostic (3.44e-3)" "unprognostic (6.64e-2)" "unprognostic (2.23e-2)" "unprognostic (3.71e-1)" "unprognostic (1.15e-2)" "unprognostic (3.75e-3)" "unprognostic (8.83e-2)" "potential prognostic favorable (2.14e-5)" "unprognostic (2.03e-2)" "unprognostic (1.14e-1)" "unprognostic (1.36e-2)" "unprognostic (2.09e-2)" "unprognostic (3.67e-3)" "unprognostic (1.03e-2)" "unprognostic (2.46e-3)" "unprognostic (2.28e-2)" "unprognostic (4.88e-2)" "unprognostic (1.74e-2)" "potential prognostic unfavorable (1.51e-7)" "unprognostic (2.37e-3)" "unprognostic (1.28e-1)" "unprognostic (3.66e-1)" "potential prognostic unfavorable (2.06e-5)" "unprognostic (3.77e-2)" "potential prognostic unfavorable (5.50e-5)" "unprognostic (2.43e-2)" "unprognostic (3.23e-1)" "unprognostic (8.28e-2)" NT5M "dNT-2, dNT2, mdN" ENSG00000205309 "5',3'-nucleotidase, mitochondrial" Q9NPB1 17 17303335-17347663 "Metabolic proteins, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.9;skeletal muscle: 12.4" "Group enriched" "Detected in many" 5 "Megakaryocytes: 222.5;Platelets: 723.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 1.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043777 Uncertain NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 47: Leukemia - Hemostasis" "Cluster 47: Platelets - Hemostasis" "HPA043777: " "unprognostic (9.28e-2)" "unprognostic (1.62e-1)" "unprognostic (6.39e-3)" "unprognostic (6.22e-2)" "unprognostic (1.96e-1)" "unprognostic (1.95e-1)" "unprognostic (2.32e-1)" "unprognostic (1.73e-1)" "unprognostic (7.79e-3)" "unprognostic (1.26e-1)" "unprognostic (1.26e-2)" "unprognostic (4.74e-3)" "unprognostic (2.58e-1)" "unprognostic (4.19e-2)" "unprognostic (2.46e-1)" NTAN1 ENSG00000157045 "N-terminal asparagine amidase" Q96AB6 16 15037854-15056079 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Kupffer cells: 42.0;Lymphatic endothelial cells: 48.1;Oocytes: 92.1;Platelets: 40.8;Urothelial cells: 36.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 17.6" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051418 Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 74: Non-specific - Signal transduction" "Cluster 14: Neurons - Synaptic function" "Cluster 54: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 4 Nucleoplasm "Golgi apparatus" "HPA051418: " "unprognostic (3.41e-3)" "unprognostic (3.11e-3)" "unprognostic (6.90e-2)" "unprognostic (7.64e-3)" "potential prognostic unfavorable (2.45e-4)" "potential prognostic unfavorable (1.13e-4)" "unprognostic (8.35e-3)" "unprognostic (2.66e-2)" "unprognostic (2.80e-2)" "unprognostic (2.94e-2)" "unprognostic (2.44e-1)" "unprognostic (1.54e-1)" "unprognostic (9.36e-3)" "unprognostic (2.04e-1)" "unprognostic (7.79e-2)" "unprognostic (7.21e-2)" "unprognostic (1.29e-2)" "unprognostic (1.22e-1)" "unprognostic (5.34e-1)" NTAQ1 "C8orf32, FLJ10204, WDYHV1" ENSG00000156795 "N-terminal glutamine amidase 1" Q96HA8 8 123416726-123470028 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024823, HPA053680" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 94: Gonadal somatic cells - Mixed function" 329 Nucleoplasm Vesicles "HPA024823: , HPA053680: " "unprognostic (1.44e-1)" "unprognostic (1.65e-2)" "unprognostic (6.33e-2)" "unprognostic (4.95e-2)" "unprognostic (4.16e-2)" "unprognostic (1.89e-1)" "unprognostic (1.03e-2)" "unprognostic (1.75e-2)" "unprognostic (5.81e-3)" "unprognostic (9.68e-2)" "unprognostic (2.09e-1)" "unprognostic (1.97e-2)" "potential prognostic unfavorable (7.54e-4)" "potential prognostic unfavorable (7.62e-4)" "unprognostic (5.24e-2)" "unprognostic (5.82e-2)" "unprognostic (7.66e-2)" "unprognostic (4.14e-2)" "unprognostic (1.01e-1)" "unprognostic (1.58e-1)" "potential prognostic unfavorable (1.80e-5)" "unprognostic (2.94e-1)" "unprognostic (1.68e-1)" "unprognostic (2.26e-1)" "unprognostic (2.97e-1)" "unprognostic (2.62e-2)" "unprognostic (2.85e-1)" "unprognostic (3.32e-2)" "unprognostic (2.35e-1)" NTF3 NGF2 ENSG00000185652 "Neurotrophin 3" P20783 12 5432108-5521536 "Cancer-related genes, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 26.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 27.0;Breast myoepithelial cells: 29.3;Epididymal basal cells: 27.8;Hepatic stellate cells: 109.7;Ovarian stromal cells: 33.8;Pericytes: 24.7;Pituitary stem cells: 59.9;Salivary myoepithelial cells: 33.9;Smooth muscle cells: 50.7;Vascular smooth muscle cells: 78.0" "Cell type enhanced" "Detected in some" "fibroblast: 23.2;hippocampal dentate gyrus: 51.6;vascular associated smooth muscle cell: 40.3" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 6.7" "Group enriched" "Detected in some" 7 "cerebellum: 6.9;cerebral cortex: 2.5;hippocampal formation: 2.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Adrenal gland - Smooth muscle cells, Kidney - Fibroblasts, Lung - Smooth muscle cells" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "cerebellum: 6.5;cerebral cortex: 2.6;hippocampal formation: 3.0" HPA032001 Uncertain Approved Vesicles "Secreted in other tissues" "Growth factor" NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 35: Non-specific - DNA binding" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 11 Vesicles "HPA032001: " "unprognostic (3.89e-2)" "unprognostic (1.92e-2)" "unprognostic (5.98e-3)" "unprognostic (7.53e-3)" "unprognostic (3.11e-2)" "unprognostic (4.26e-2)" "unprognostic (5.08e-2)" "unprognostic (5.57e-2)" "unprognostic (2.74e-1)" "unprognostic (3.29e-1)" "unprognostic (3.57e-1)" "unprognostic (7.63e-2)" "unprognostic (1.11e-2)" "unprognostic (1.28e-1)" "unprognostic (1.30e-1)" NTF4 "GLC1O, NT-4/5, NTF5" ENSG00000225950 "Neurotrophin 4" P34130 19 49061066-49065076 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Cancer-related genes, Glaucoma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 19.7;skeletal muscle: 13.5;skin 1: 15.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 13.9" "Adipose visceral - Mesothelial cells, Prostate - Prostate basal glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA049376 Approved "Golgi apparatus" "Secreted in other tissues" "Growth factor" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" 7 "Golgi apparatus" "HPA049376: " "unprognostic (1.83e-1)" "unprognostic (1.72e-2)" "unprognostic (3.31e-1)" "unprognostic (4.02e-2)" "unprognostic (3.95e-2)" "unprognostic (3.79e-2)" "unprognostic (9.51e-2)" "unprognostic (3.47e-1)" "unprognostic (2.26e-1)" "unprognostic (1.24e-3)" "unprognostic (2.81e-1)" "potential prognostic unfavorable (7.50e-5)" "unprognostic (5.13e-3)" "unprognostic (9.38e-2)" "unprognostic (1.83e-1)" "unprognostic (1.56e-2)" "unprognostic (8.69e-3)" NTHL1 "NTH1, OCTS3" ENSG00000065057 "Nth like DNA glycosylase 1" P78549 16 2039815-2047866 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "Glycosidase, Hydrolase, Lyase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 13 "Hepatocytes: 1087.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025152 Supported NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 64: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 93: Hepatocytes - Bile production & excretion" 5 "CAB025152: " "unprognostic (1.59e-2)" "unprognostic (5.46e-2)" "unprognostic (6.80e-2)" "unprognostic (5.09e-3)" "unprognostic (3.79e-1)" "unprognostic (1.70e-1)" "unprognostic (2.43e-1)" "unprognostic (8.69e-2)" "unprognostic (4.39e-1)" "unprognostic (2.86e-1)" "unprognostic (5.66e-2)" "unprognostic (4.30e-2)" "unprognostic (7.37e-2)" "unprognostic (7.40e-2)" "unprognostic (8.16e-2)" "unprognostic (1.08e-1)" "unprognostic (8.97e-2)" "unprognostic (4.45e-1)" "unprognostic (4.57e-2)" "unprognostic (2.15e-1)" "unprognostic (2.25e-1)" "unprognostic (1.44e-1)" "unprognostic (3.42e-1)" "unprognostic (1.86e-1)" "unprognostic (2.24e-2)" "unprognostic (1.15e-1)" "unprognostic (1.69e-1)" "unprognostic (1.56e-1)" "unprognostic (4.83e-2)" "unprognostic (3.45e-2)" "unprognostic (2.50e-1)" NTM "CEPU-1, HNT, IGLON2, NTRI" ENSG00000182667 Neurotrimin Q9P121 11 131370478-132336822 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 83.3;retina: 67.0" "Cell type enhanced" "Detected in many" "Astrocytes: 3562.3;Bergmann glia: 2846.0;Brain excitatory neurons: 1042.3;Brain inhibitory neurons: 859.4;Cone photoreceptor cells: 2978.9;Mast cells: 1326.0;Oligodendrocyte progenitor cells: 2832.2;Oligodendrocytes: 1946.6;Retinal amacrine cells: 960.7;Retinal bipolar cells: 735.2;Retinal ganglion cells: 1019.8;Rod photoreceptor cells: 4173.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 32.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 175 "plasmacytoid DC: 17.5" "Lineage enriched" "Detected in single" 175 "dendritic cells: 17.5" "Cancer enhanced" "Detected in many" "Bone cancer: 21.7;Brain cancer: 21.9;Sarcoma: 22.1;thyroid cancer: 21.7" "Adrenal gland - Adrenal cortex cells, Colon - Enteric glia cells, Minor Salivary Gland - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB024875 Enhanced "Intracellular and membrane" "Cell adhesion" NA NA 3300000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 79: Photoreceptor cells - Phototransduction" 4 "CAB024875: " "unprognostic (8.59e-2)" "unprognostic (1.11e-1)" "unprognostic (2.76e-1)" "unprognostic (2.44e-2)" "potential prognostic unfavorable (4.81e-4)" "unprognostic (4.54e-2)" "unprognostic (1.65e-1)" "unprognostic (1.90e-2)" "unprognostic (7.32e-2)" "unprognostic (2.69e-1)" "unprognostic (9.28e-3)" "unprognostic (2.92e-1)" "unprognostic (1.71e-2)" "unprognostic (8.62e-3)" "unprognostic (1.36e-1)" "unprognostic (3.18e-1)" "unprognostic (2.12e-3)" "unprognostic (6.67e-2)" "unprognostic (1.56e-2)" "unprognostic (6.36e-3)" "potential prognostic unfavorable (8.25e-7)" "unprognostic (1.35e-2)" "unprognostic (3.02e-1)" "unprognostic (2.59e-2)" "unprognostic (8.27e-2)" "unprognostic (6.99e-3)" "unprognostic (3.97e-2)" "unprognostic (5.96e-3)" "unprognostic (6.99e-2)" "unprognostic (2.52e-1)" "unprognostic (5.57e-2)" NTMT1 "AD-003, C9orf32, HOMT1A, METTL11A, NRMT, NRMT1" ENSG00000148335 "N-terminal Xaa-Pro-Lys N-methyltransferase 1" Q9BV86 9 129608884-129636135 "Enzymes, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 417.0;Late primary spermatocytes: 361.9;Late spermatids: 1076.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020092, HPA058420" Uncertain Enhanced Nucleoplasm,Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 67: Testis - Mixed function" "Cluster 45: Non-specific - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 8 Nucleoplasm Cytosol "HPA020092: , HPA058420: " "unprognostic (2.33e-2)" "unprognostic (4.72e-3)" "unprognostic (9.41e-2)" "unprognostic (1.53e-1)" "unprognostic (5.03e-2)" "unprognostic (3.37e-1)" "unprognostic (5.28e-3)" "potential prognostic unfavorable (1.07e-4)" "unprognostic (1.27e-1)" "potential prognostic favorable (1.22e-4)" "unprognostic (1.23e-1)" "unprognostic (2.33e-2)" "unprognostic (1.83e-3)" "unprognostic (3.05e-2)" "unprognostic (1.23e-1)" "unprognostic (1.02e-1)" "unprognostic (1.62e-1)" "unprognostic (1.49e-2)" "unprognostic (9.71e-2)" "unprognostic (5.78e-1)" "unprognostic (6.19e-1)" "unprognostic (2.28e-2)" "unprognostic (4.06e-2)" "unprognostic (1.43e-1)" "unprognostic (3.17e-2)" "potential prognostic favorable (3.94e-4)" "unprognostic (2.16e-1)" "unprognostic (1.17e-1)" "unprognostic (5.21e-2)" NTMT2 "C1orf184, HOMT1B, METTL11B" ENSG00000203740 "N-terminal Xaa-Pro-Lys N-methyltransferase 2" Q5VVY1 1 170145959-170168866 "Enzymes, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "heart muscle: 1.6" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 11.8;Late primary spermatocytes: 1.1;Leydig cells: 1.3;Myonuclei: 3.0;Sertoli cells: 1.1;Undifferentiated spermatogonia: 2.9" "Cell type enhanced" "Detected in single" "splatter: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA028049 Uncertain NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" "HPA028049: " NTN1 "NET1, NTN1L" ENSG00000065320 "Netrin 1" O95631 17 9021510-9244000 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Apoptosis "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 35.5;heart muscle: 56.1" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 301.9;Epididymal clear cells: 249.0;Ocular epithelial cells: 218.8;Oligodendrocyte progenitor cells: 251.4;Renal collecting duct intercalated cells: 382.2;Respiratory basal cells: 534.7;Respiratory deuterosomal cells: 353.5;Respiratory ionocytes: 264.2;Respiratory secretory cells: 420.8;Salivary duct cells: 327.7;Smooth muscle cells: 260.8" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 205.6;ependymal cell: 189.7;oligodendrocyte precursor cell: 308.7;vascular associated smooth muscle cell: 205.8" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 39.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 22.3" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Breast - Fibroblasts, Prostate - Prostate basal glandular cells, Skin - Fibroblasts_2, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056419 Approved Approved "Nucleoplasm,Actin filaments,Cytosol" "Secreted to extracellular matrix" Other NA NA 2200000 "Cluster 35: Non-specific - Mixed function" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 4 Cytosol "Nucleoplasm, Actin filaments" "HPA056419: " "unprognostic (5.80e-2)" "unprognostic (1.38e-1)" "unprognostic (4.75e-1)" "unprognostic (8.19e-2)" "unprognostic (1.41e-1)" "unprognostic (1.36e-1)" "unprognostic (2.43e-1)" "unprognostic (1.86e-1)" "unprognostic (2.27e-3)" "unprognostic (5.22e-2)" "unprognostic (3.31e-3)" "unprognostic (3.41e-2)" "unprognostic (1.10e-1)" "unprognostic (1.22e-2)" "unprognostic (4.45e-1)" "unprognostic (1.06e-1)" "unprognostic (6.75e-2)" "unprognostic (1.45e-1)" "unprognostic (7.33e-3)" "unprognostic (3.08e-1)" "unprognostic (2.80e-1)" "unprognostic (3.29e-1)" "unprognostic (8.67e-2)" "unprognostic (7.47e-2)" "unprognostic (3.52e-2)" "unprognostic (9.24e-2)" "unprognostic (1.07e-2)" "unprognostic (2.07e-1)" "unprognostic (1.65e-1)" NTN3 NTN2L ENSG00000162068 "Netrin 3" O00634 16 2471297-2474145 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 2.3;Neuroblastoma: 3.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA050817 Uncertain "Secreted in brain" "No annotated function" NA NA "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 1: Neuronal - Visual perception" "HPA050817: " NTN4 ENSG00000074527 "Netrin 4" Q9HB63 12 95657807-95791189 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 171.0" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 362.9;Breast hormone-responsive cells: 385.8;Loop of henle epithelial cells: 404.9;Papillary tip epithelial cells: 490.2;Renal collecting duct principal cells: 634.5;Urothelial cells: 389.1" "Cell type enhanced" "Detected in many" "vascular associated smooth muscle cell: 489.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 12 "MAIT T-cell: 1.6" "Lineage enriched" "Detected in single" 16 "T-cells: 1.6" "Low cancer specificity" "Detected in many" "Adipose visceral - Endothelial cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Prostate - Prostate basal glandular cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049832 Approved "Secreted to extracellular matrix" "No annotated function" NA NA "Cluster 66: Lymphoid tissue - Immune response" "Cluster 53: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 9 "HPA049832: " "unprognostic (2.47e-3)" "unprognostic (2.04e-1)" "unprognostic (1.34e-1)" "unprognostic (5.60e-2)" "unprognostic (1.46e-1)" "unprognostic (1.17e-1)" "unprognostic (6.14e-2)" "unprognostic (7.96e-3)" "unprognostic (6.19e-2)" "unprognostic (1.28e-1)" "validated prognostic favorable (5.45e-11)" "validated prognostic favorable (9.79e-4)" "unprognostic (7.14e-3)" "unprognostic (2.67e-1)" "unprognostic (4.05e-3)" "unprognostic (1.11e-1)" "unprognostic (1.87e-2)" "unprognostic (1.29e-2)" "unprognostic (1.89e-1)" "unprognostic (7.15e-2)" "unprognostic (1.00e-1)" "potential prognostic unfavorable (4.38e-4)" "unprognostic (2.20e-1)" "unprognostic (3.18e-1)" "unprognostic (6.16e-2)" "unprognostic (8.41e-2)" "unprognostic (5.46e-2)" "unprognostic (2.65e-2)" "unprognostic (6.27e-2)" "unprognostic (2.32e-1)" "unprognostic (9.66e-2)" NTN5 ENSG00000142233 "Netrin 5" Q8WTR8 19 48661407-48673081 "Predicted intracellular proteins, Predicted secreted proteins" Neurogenesis "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "pituitary gland: 4.8" "Cell type enhanced" "Detected in many" "Astrocytes: 6.8;Early spermatids: 14.3;Ependymal cells: 7.1;Gonadotrophs: 10.1;Lactotrophs: 8.1;Late spermatids: 18.5;Retinal amacrine cells: 7.6;Retinal horizontal cells: 18.0;Somatotrophs: 11.6;Thyrotrophs: 8.7" "Cell type enhanced" "Detected in many" "astrocyte: 9.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "Sarcoma: 4.3" "Region enhanced" "Detected in some" "cerebral cortex: 3.5" "Region enriched" "Detected in some" 5 "cerebellum: 5.0" "Secreted in brain" "Developmental protein" NA NA "Cluster 64: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" "unprognostic (4.50e-1)" "unprognostic (1.24e-1)" "unprognostic (1.68e-1)" NTNG1 "KIAA0976, Lmnt1" ENSG00000162631 "Netrin G1" Q9Y2I2 1 107140007-107484923 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 9.2;kidney: 8.3;retina: 9.5" "Cell type enriched" "Detected in many" 4 "Podocytes: 3414.9" "Cell type enhanced" "Detected in all" "thalamic excitatory: 2777.8" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 5.0" "Region enhanced" "Detected in all" "thalamus: 164.8" "Immune cell enriched" "Detected in single" 4 "memory B-cell: 1.1" "Lineage enriched" "Detected in single" 4 "B-cells: 1.1" "Cancer enhanced" "Detected in many" "Bone cancer: 10.1" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Kidney - Podocytes, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "hippocampal formation: 26.0;midbrain: 79.9;pons: 71.8;thalamus: 99.3" HPA065954 Supported "Plasma membrane" "Intracellular and membrane" "Developmental protein" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 57: Podocytes - Glomerular filtration" 5 "Plasma membrane" "HPA065954: " "unprognostic (4.68e-2)" "unprognostic (2.19e-2)" "unprognostic (7.07e-3)" "unprognostic (3.22e-1)" "unprognostic (1.82e-1)" "unprognostic (7.66e-2)" "unprognostic (1.00e-2)" NTNG2 "KIAA1857, Lmnt2, NTNG1" ENSG00000196358 "Netrin G2" Q96CW9 9 132162058-132244526 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Autism spectrum disorder, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 23.6;brain: 19.6;retina: 19.3" "Cell type enhanced" "Detected in many" "Astrocytes: 54.6;Bergmann glia: 113.2;Cone photoreceptor cells: 171.8;Neutrophil progenitors: 167.8;Neutrophils: 110.4;Retinal bipolar cells: 95.5;Retinal ganglion cells: 46.4;Rod photoreceptor cells: 128.8" "Cell type enhanced" "Detected in many" "Bergmann glia: 126.1;deep-layer intratelencephalic: 87.4" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 4.2" "Region enhanced" "Detected in all" "cerebral cortex: 149.3" "Immune cell enriched" "Detected in single" 5 "neutrophil: 1.1" "Lineage enriched" "Detected in single" 11 "granulocytes: 1.1" "Cancer enhanced" "Detected in some" "Leukemia: 4.7" "Prostate - Prostate glandular cells, Skin - Fibroblasts_2, Spleen - Neutrophils_2, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024306, HPA071290" Approved Uncertain "Vesicles,Plasma membrane" "Intracellular and membrane" "Developmental protein" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 1 Vesicles "Plasma membrane" "HPA024306: , HPA071290: " "unprognostic (2.56e-1)" "unprognostic (1.68e-1)" "unprognostic (2.85e-1)" "potential prognostic favorable (1.34e-4)" "unprognostic (1.02e-1)" "unprognostic (6.62e-2)" "unprognostic (5.02e-2)" "unprognostic (9.72e-2)" "potential prognostic favorable (1.98e-4)" "potential prognostic favorable (5.53e-4)" NTPCR "C1orf57, HCR-NTPase, MGC13186, THEP1" ENSG00000135778 "Nucleoside-triphosphatase, cancer-related" Q9BSD7 1 232950605-232983882 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028125, HPA054304" Uncertain Approved Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 97: Non-specific - Cellular respiration" 16 Cytosol "HPA028125: , HPA054304: " "unprognostic (2.36e-2)" "unprognostic (1.48e-1)" "unprognostic (3.07e-2)" "unprognostic (4.43e-2)" "unprognostic (3.03e-1)" "unprognostic (1.13e-1)" "unprognostic (3.90e-2)" "unprognostic (4.57e-2)" "unprognostic (3.53e-2)" "unprognostic (3.17e-3)" "unprognostic (1.26e-2)" "potential prognostic unfavorable (8.16e-4)" "potential prognostic unfavorable (5.81e-4)" "unprognostic (7.09e-3)" "unprognostic (2.33e-1)" "unprognostic (7.57e-2)" "unprognostic (1.10e-1)" "unprognostic (1.83e-1)" "unprognostic (3.83e-1)" "unprognostic (2.25e-2)" "unprognostic (1.97e-3)" "unprognostic (9.58e-2)" "unprognostic (2.09e-1)" "unprognostic (2.62e-1)" "unprognostic (3.97e-1)" "unprognostic (1.34e-1)" "unprognostic (3.59e-1)" "unprognostic (1.83e-1)" "unprognostic (4.08e-3)" "unprognostic (9.56e-2)" NTRK1 "MTC, TRK, TRKA" ENSG00000198400 "Neurotrophic receptor tyrosine kinase 1" P04629 1 156815636-156881850 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Differentiation, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 6.6" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 31.9;Decidual stromal cells: 19.7;Fibro-adipogenic progenitors: 20.8;Mast cells: 34.7;Megakaryocyte-Erythroid progenitors: 13.8;Other brain neurons: 19.0;Platelets: 15.5;Renal collecting duct intercalated cells: 18.8;Retinal bipolar cells: 49.9;Retinal horizontal cells: 52.1" "Cell type enhanced" "Detected in many" "fibroblast: 21.3;lower rhombic lip: 25.4" "Not detected" "Not detected" "Group enriched" "Detected in all" 5 "cerebral cortex: 23.8;medulla oblongata: 30.7;pons: 47.8" "Immune cell enriched" "Detected in single" 116 "basophil: 94.9" "Lineage enriched" "Detected in single" 772 "granulocytes: 94.9" "Group enriched" "Detected in some" 8 "Leukemia: 9.0;Neuroblastoma: 17.4" "Adrenal gland - Adrenal medulla cells, Kidney - Intercalated cells, Lung - Mast cells, Stomach - Fibroblasts" "Region enhanced" "Detected in many" "basal ganglia: 8.4" "Region enriched" "Detected in single" 6 "basal ganglia: 5.4" "CAB004606, HPA035799, HPA076570, CAB080140" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 145 "Vesicles, Cytosol" "CAB004606: , CAB080140: , HPA035799: , HPA076570: " "unprognostic (2.30e-2)" "unprognostic (3.70e-2)" NTRK2 TRKB ENSG00000148053 "Neurotrophic receptor tyrosine kinase 2" Q16620 9 84668375-85095751 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Differentiation, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, Epilepsy, FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 233.3;thyroid gland: 118.0" "Cell type enhanced" "Detected in many" "Astrocytes: 2373.3;Bergmann glia: 364.4;Brain excitatory neurons: 502.7;Brain inhibitory neurons: 585.1;Breast lactating cells: 558.5;Choroid plexus epithelial cells: 430.8;Ependymal cells: 1515.5;Oligodendrocyte progenitor cells: 780.5;Retinal horizontal cells: 751.3;Vascular smooth muscle cells: 473.6" "Cell type enhanced" "Detected in all" "astrocyte: 2595.8" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 135.6;Thyroid Carcinoma (TCGA): 104.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 8.8;Esophageal cancer: 9.1" "Breast - Breast myoepithelial cells, Liver - Hepatic stellate cells, Minor Salivary Gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007637, CAB010346, HPA074873" Enhanced Supported "Vesicles,Plasma membrane,Primary cilium tip" NA NA 1700000 "Cluster 73: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 7: Liver cancer - Metabolism" "Cluster 28: Astrocytes - Homeostasis & neuron support" 25 "Plasma membrane" "Vesicles, Primary cilium tip" "CAB010346: , HPA007637: , HPA074873: " "unprognostic (1.74e-1)" "unprognostic (1.65e-3)" "unprognostic (4.55e-2)" "unprognostic (9.27e-2)" "unprognostic (4.97e-2)" "unprognostic (6.57e-2)" "unprognostic (1.93e-1)" "unprognostic (6.15e-2)" "unprognostic (3.51e-2)" "unprognostic (1.48e-3)" "potential prognostic favorable (1.81e-4)" "unprognostic (9.59e-2)" "unprognostic (2.95e-2)" "unprognostic (3.52e-2)" "unprognostic (1.51e-2)" "unprognostic (1.90e-2)" "unprognostic (2.15e-1)" "unprognostic (5.05e-2)" "unprognostic (2.15e-1)" "unprognostic (2.23e-2)" "unprognostic (2.71e-1)" "unprognostic (5.08e-3)" "unprognostic (8.42e-3)" "unprognostic (1.99e-2)" "unprognostic (2.25e-2)" "unprognostic (8.57e-2)" "unprognostic (3.68e-2)" NTRK3 TRKC ENSG00000140538 "Neurotrophic receptor tyrosine kinase 3" Q16288 15 87859751-88256791 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "blood vessel: 66.9;brain: 27.9" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 244.6;Astrocytes: 535.0;Bergmann glia: 667.1;Brain excitatory neurons: 469.7;Brain inhibitory neurons: 466.5;Early spermatids: 231.8;Late spermatids: 226.3;Oligodendrocyte progenitor cells: 830.2;Other brain neurons: 258.7;Retinal amacrine cells: 246.7;Retinal ganglion cells: 274.3;Vascular smooth muscle cells: 613.8" "Cell type enhanced" "Detected in all" "fibroblast: 2426.8" "Group enriched" "Detected in many" 5 "Glioblastoma Multiforme (TCGA): 22.8;Testicular Germ Cell Tumor (TCGA): 9.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 7.1;Neuroblastoma: 7.8;thyroid cancer: 5.2" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Heart muscle - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009233, HPA027484, HPA048065" Approved Supported "Nuclear membrane,Nucleoli,Nucleoli rim" NA NA 690000 "Cluster 74: Non-specific - Signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 62: Smooth muscle cells - Muscle contraction" 59 "Nucleoli, Nucleoli rim" "Nuclear membrane" "CAB009233: , HPA027484: , HPA048065: " "potential prognostic favorable (6.86e-4)" "unprognostic (3.83e-1)" "unprognostic (1.58e-1)" "unprognostic (7.07e-3)" "unprognostic (1.03e-1)" "unprognostic (2.59e-2)" "unprognostic (4.23e-2)" "unprognostic (1.83e-1)" "unprognostic (2.44e-1)" "unprognostic (2.48e-1)" "unprognostic (1.58e-1)" "unprognostic (3.90e-3)" "unprognostic (1.91e-2)" NTS ENSG00000133636 Neurotensin P30990 12 85874295-85882992 "Predicted secreted proteins" Vasoactive "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "intestine: 156.1" "Cell type enriched" "Detected in some" 11 "Neuroendocrine cells: 6928.2" "Group enriched" "Detected in many" 5 "ependymal cell: 297.4;thalamic excitatory: 80.1" "Cancer enhanced" "Detected in many" "Lung Squamous Cell Carcinoma (TCGA): 482.3" "Group enriched" "Detected in all" 4 "cerebral cortex: 20.0;hypothalamus: 44.0;medulla oblongata: 27.4;midbrain: 20.6;thalamus: 59.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 286.9;ovarian cancer: 348.2;testis cancer: 189.3" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "basal ganglia: 88.3" "HPA026664, HPA071012" Enhanced Supported Vesicles "Secreted to digestive system" Other NA NA 1100000 "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 38: Sub-cortical - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" 2 Vesicles "HPA026664: , HPA071012: " "potential prognostic unfavorable (9.70e-4)" "unprognostic (1.22e-1)" "unprognostic (2.23e-2)" "unprognostic (2.20e-3)" "unprognostic (1.97e-1)" "unprognostic (1.96e-1)" "unprognostic (2.14e-1)" "unprognostic (4.52e-1)" "unprognostic (2.29e-3)" "potential prognostic favorable (9.84e-4)" "unprognostic (6.07e-2)" "unprognostic (9.06e-2)" "unprognostic (5.65e-3)" "unprognostic (1.98e-2)" "unprognostic (1.05e-2)" "unprognostic (1.04e-3)" "unprognostic (1.10e-1)" "unprognostic (5.43e-2)" "unprognostic (1.02e-2)" "unprognostic (2.26e-3)" "unprognostic (1.58e-2)" "unprognostic (2.83e-2)" "unprognostic (4.63e-2)" "unprognostic (2.75e-1)" "unprognostic (1.35e-2)" NTSR1 NTR ENSG00000101188 "Neurotensin receptor 1" P30989 20 62708836-62762771 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "intestine: 9.8" "Cell type enhanced" "Detected in some" "Epicardial cells: 6.8;Kupffer cells: 5.1;monocytes: 15.2;Müller glia: 8.6;Neutrophil progenitors: 5.0;Neutrophils: 33.0;Renal collecting duct principal cells: 5.3;Renal connecting tubule cells: 5.5;Retinal bipolar cells: 17.7;Rod photoreceptor cells: 7.7" "Cell type enhanced" "Detected in many" "midbrain-derived inhibitory: 15.5;miscellaneous: 19.2" "Cancer enhanced" "Detected in some" "Pancreatic Adenocarcinoma (TCGA): 1.7;Stomach Adenocarcinoma (TCGA): 2.4" "Region enriched" "Detected in many" 6 "midbrain: 25.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 11.8;Gastric cancer: 13.5;pancreatic cancer: 19.5" "Kidney - Ascending Loop of Henle cells, Lung - Neutrophils_2, Spleen - Neutrophils_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA050299 Supported "Plasma membrane" NA NA "Cluster 77: Intestine - Digestion" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 22 "Plasma membrane" "HPA050299: " "unprognostic (1.42e-1)" "unprognostic (8.27e-3)" "unprognostic (8.53e-3)" "unprognostic (2.49e-1)" NTSR2 NTR2 ENSG00000169006 "Neurotensin receptor 2" O95665 2 11658178-11670195 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 50 "brain: 108.3" "Cell type enriched" "Detected in some" 4 "Astrocytes: 55.0" "Cell type enriched" "Detected in some" 25 "astrocyte: 65.2" "Cancer enriched" "Detected in single" 18 "Glioblastoma Multiforme (TCGA): 10.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Adipocytes (Visceral)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 28: Astrocytes - Homeostasis & neuron support" "unprognostic (4.77e-2)" "unprognostic (3.40e-1)" NUAK1 "ARK5, KIAA0537" ENSG00000074590 "NUAK family kinase 1" O60285 12 106063345-106138954 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, DNA damage" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bergmann glia: 152.5;Brain excitatory neurons: 85.0;Cardiomyocytes: 85.3;Microglia: 186.8;Oligodendrocytes: 95.6;Vascular endothelial cells: 255.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Endothelial cells, Minor Salivary Gland - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057143 Supported "Nucleoplasm,Nucleoli fibrillar center,Microtubules,Mitotic spindle,Primary cilium" Yes No "Cluster 25: Non-specific - Basic cellular processes" "Cluster 53: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 21 "Nucleoli fibrillar center" "Nucleoplasm, Microtubules, Mitotic spindle, Primary cilium" "HPA057143: " "unprognostic (2.45e-1)" "unprognostic (1.01e-1)" "unprognostic (3.92e-2)" "unprognostic (1.04e-1)" "unprognostic (1.10e-2)" "unprognostic (1.10e-2)" "unprognostic (1.40e-1)" "unprognostic (3.45e-1)" "unprognostic (2.18e-1)" "unprognostic (1.30e-2)" "unprognostic (2.09e-3)" "unprognostic (6.09e-2)" "unprognostic (2.78e-1)" "unprognostic (9.92e-2)" "unprognostic (5.81e-2)" "unprognostic (8.72e-2)" "unprognostic (2.17e-3)" "unprognostic (1.03e-1)" "unprognostic (2.64e-1)" "unprognostic (1.01e-3)" "potential prognostic unfavorable (9.57e-8)" "unprognostic (5.36e-1)" "unprognostic (2.19e-2)" "unprognostic (8.61e-2)" "unprognostic (1.69e-1)" "unprognostic (2.57e-3)" "unprognostic (3.40e-1)" "unprognostic (1.47e-2)" "unprognostic (7.63e-2)" "unprognostic (7.08e-2)" "unprognostic (3.89e-2)" NUAK2 "FLJ90349, SNARK" ENSG00000163545 "NUAK family kinase 2" Q9H093 1 205302063-205321745 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 37.5;esophagus: 55.1;vagina: 42.5" "Cell type enhanced" "Detected in many" "Endometrial luminal cells: 98.0;Epididymal efferent duct absorptive cells: 215.4;Epididymal efferent duct ciliated cells: 102.0;Esophageal apical cells: 561.1;Esophageal suprabasal cells: 104.6;Ocular epithelial cells: 129.3;Pancreatic duct cells: 143.6" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 18.2;ependymal cell: 10.6;leukocyte: 11.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 120.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Pancreas - Ductal cells, Skin - Keratinocyte (other), Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA008958 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 5 "Nucleoplasm, Cytosol" "HPA008958: " "unprognostic (3.29e-1)" "unprognostic (7.45e-2)" "unprognostic (1.16e-1)" "unprognostic (1.47e-1)" "unprognostic (5.87e-2)" "unprognostic (7.23e-2)" "unprognostic (6.08e-3)" "potential prognostic unfavorable (3.34e-4)" "unprognostic (7.99e-3)" "unprognostic (1.43e-2)" "unprognostic (5.44e-2)" "unprognostic (1.23e-1)" "unprognostic (2.36e-2)" "unprognostic (3.35e-2)" "unprognostic (5.75e-2)" "unprognostic (1.60e-3)" "unprognostic (8.96e-2)" "unprognostic (3.10e-2)" "unprognostic (5.72e-3)" "unprognostic (1.29e-1)" "unprognostic (4.68e-1)" "potential prognostic favorable (2.86e-5)" "unprognostic (5.50e-2)" "unprognostic (9.40e-2)" "unprognostic (3.46e-2)" "unprognostic (1.19e-1)" "unprognostic (3.14e-1)" "unprognostic (1.74e-1)" "unprognostic (1.43e-1)" "unprognostic (4.59e-3)" "unprognostic (1.58e-2)" NUB1 "BS4, NUB1L, NYREN18" ENSG00000013374 "Negative regulator of ubiquitin like proteins 1" Q9Y5A7 7 151341772-151378449 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 212.6;Late primary spermatocytes: 393.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021220, HPA050722, HPA053648" Approved Enhanced Nucleoplasm,Nucleoli NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 47: Testis - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 82: Dendritic cells - Antigen presentation" 19 "Nucleoplasm, Nucleoli" "HPA021220: , HPA050722: , HPA053648: " "potential prognostic favorable (3.79e-4)" "unprognostic (1.66e-1)" "unprognostic (8.20e-2)" "unprognostic (1.97e-1)" "unprognostic (1.54e-1)" "unprognostic (9.24e-2)" "unprognostic (1.47e-1)" "unprognostic (7.35e-3)" "unprognostic (7.18e-2)" "potential prognostic unfavorable (6.44e-4)" "potential prognostic favorable (7.41e-6)" "unprognostic (1.01e-2)" "unprognostic (7.07e-2)" "unprognostic (6.45e-3)" "unprognostic (1.58e-1)" "unprognostic (5.06e-3)" "unprognostic (1.41e-2)" "unprognostic (3.03e-1)" "unprognostic (2.51e-1)" "unprognostic (7.79e-2)" "unprognostic (1.37e-1)" "unprognostic (3.43e-2)" "unprognostic (9.38e-2)" "unprognostic (1.23e-2)" "unprognostic (1.75e-2)" "unprognostic (1.74e-2)" "unprognostic (5.29e-1)" "unprognostic (1.51e-1)" "unprognostic (1.01e-1)" "unprognostic (1.23e-1)" "unprognostic (8.45e-3)" NUBP1 "CIAO5, NBP1, NBP35" ENSG00000103274 "NUBP iron-sulfur cluster assembly factor 1, cytosolic" P53384 16 10743786-10769351 "Essential proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041656, HPA041799" Enhanced Supported "Golgi apparatus,Centrosome,Cytosol,Mid piece,Principal piece,End piece" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 54: Non-specific - Transcription" "Cluster 82: Dendritic cells - Antigen presentation" 3 "Cytosol, Mid piece, Principal piece, End piece" "Golgi apparatus, Centrosome" "HPA041656: , HPA041799: " "unprognostic (1.43e-1)" "unprognostic (1.16e-1)" "unprognostic (1.00e-1)" "unprognostic (2.92e-2)" "unprognostic (8.45e-2)" "unprognostic (1.84e-1)" "unprognostic (1.72e-2)" "unprognostic (2.10e-2)" "unprognostic (2.11e-2)" "unprognostic (3.78e-2)" "potential prognostic favorable (1.27e-6)" "unprognostic (1.15e-2)" "unprognostic (2.87e-3)" "unprognostic (1.75e-1)" "unprognostic (3.01e-2)" "unprognostic (3.18e-1)" "unprognostic (9.91e-2)" "unprognostic (1.33e-1)" "unprognostic (3.90e-1)" "unprognostic (1.53e-1)" "unprognostic (2.49e-1)" "unprognostic (2.04e-1)" "unprognostic (4.78e-1)" "unprognostic (4.29e-2)" "unprognostic (7.89e-2)" "unprognostic (5.59e-2)" "unprognostic (3.17e-1)" "unprognostic (3.53e-2)" "unprognostic (2.07e-1)" "unprognostic (2.90e-1)" "unprognostic (5.65e-2)" NUBP2 "CFD1, CIAO6" ENSG00000095906 "NUBP iron-sulfur cluster assembly factor 2, cytosolic" Q9Y5Y2 16 1782932-1789186 "Essential proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 129.1;Late spermatids: 169.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041704 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 70: Non-specific - Protein processing" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 54: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 39 "Nucleoplasm, Cytosol" "HPA041704: " "unprognostic (1.68e-1)" "unprognostic (7.19e-3)" "unprognostic (1.48e-1)" "unprognostic (2.63e-1)" "unprognostic (2.66e-1)" "unprognostic (3.49e-1)" "unprognostic (2.54e-1)" "potential prognostic favorable (2.27e-4)" "unprognostic (1.39e-1)" "unprognostic (5.21e-2)" "unprognostic (1.07e-2)" "unprognostic (5.22e-3)" "unprognostic (2.76e-1)" "unprognostic (5.04e-3)" "unprognostic (2.07e-2)" "unprognostic (7.33e-2)" "unprognostic (5.30e-2)" "unprognostic (8.37e-2)" "unprognostic (2.26e-1)" "unprognostic (3.57e-1)" "unprognostic (1.89e-1)" "unprognostic (3.30e-1)" "unprognostic (7.44e-2)" "unprognostic (1.90e-1)" "unprognostic (7.02e-2)" "unprognostic (2.03e-1)" "unprognostic (8.70e-2)" "unprognostic (1.84e-2)" "unprognostic (7.37e-2)" "unprognostic (9.39e-2)" "unprognostic (4.05e-2)" NUBPL "C14orf127, FLJ12660, huInd1, IND1" ENSG00000151413 "NUBP iron-sulfur cluster assembly factor, mitochondrial" Q8TB37 14 31489956-31861224 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029203 Approved Supported Mitochondria NA NA "Cluster 34: B-cells - Unknown function" "Cluster 35: Non-specific - Mixed function" "Cluster 27: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 82: Dendritic cells - Antigen presentation" 19 Mitochondria "HPA029203: " "unprognostic (2.70e-1)" "unprognostic (9.47e-2)" "unprognostic (2.57e-1)" "unprognostic (1.87e-2)" "unprognostic (2.50e-2)" "unprognostic (1.83e-2)" "unprognostic (2.03e-2)" "unprognostic (4.05e-2)" "unprognostic (1.74e-3)" "potential prognostic unfavorable (6.61e-7)" "potential prognostic favorable (4.12e-7)" "unprognostic (1.47e-3)" "unprognostic (8.43e-3)" "unprognostic (2.71e-1)" "unprognostic (1.95e-1)" "unprognostic (7.93e-2)" "unprognostic (1.24e-2)" "unprognostic (2.16e-1)" "unprognostic (1.60e-1)" "unprognostic (1.78e-1)" "unprognostic (3.56e-2)" "unprognostic (1.44e-1)" "unprognostic (1.37e-2)" "unprognostic (2.29e-1)" "unprognostic (5.31e-3)" "unprognostic (4.76e-2)" "unprognostic (2.49e-1)" "unprognostic (1.38e-2)" "unprognostic (4.15e-2)" "unprognostic (1.41e-2)" "unprognostic (5.59e-2)" NUCB1 "Calnuc, NUC" ENSG00000104805 "Nucleobindin 1" Q02818 19 48900050-48923473 "Plasma proteins, Predicted secreted proteins" "DNA-binding, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Decidual stromal cells: 281.7;Enterocytes: 437.0;Esophageal apical cells: 296.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008176, HPA073500" Supported Supported "Golgi apparatus,Vesicles,Microtubules" "Secreted to blood" Other NA NA 46000000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 45: Non-specific - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 14 "Golgi apparatus" "Vesicles, Microtubules" "HPA008176: , HPA073500: " "unprognostic (4.32e-2)" "unprognostic (1.88e-1)" "unprognostic (1.20e-1)" "unprognostic (1.72e-2)" "unprognostic (2.36e-1)" "unprognostic (1.47e-1)" "unprognostic (8.08e-2)" "unprognostic (3.41e-3)" "unprognostic (1.31e-1)" "unprognostic (1.97e-1)" "potential prognostic favorable (8.44e-6)" "unprognostic (1.42e-1)" "unprognostic (5.45e-2)" "unprognostic (3.79e-2)" "unprognostic (6.42e-2)" "unprognostic (1.59e-1)" "unprognostic (1.81e-1)" "unprognostic (5.00e-3)" "unprognostic (1.08e-2)" "unprognostic (2.43e-2)" "unprognostic (2.03e-1)" "unprognostic (4.63e-2)" "unprognostic (3.71e-2)" "unprognostic (2.21e-1)" "unprognostic (1.65e-3)" "unprognostic (2.13e-1)" "unprognostic (1.95e-1)" "unprognostic (1.01e-1)" "unprognostic (2.21e-1)" "unprognostic (1.45e-2)" "unprognostic (6.57e-2)" NUCB2 NEFA ENSG00000070081 "Nucleobindin 2" P80303 11 17208153-17349980 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "DNA-binding, Guanine-nucleotide releasing factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 465.9;salivary gland: 478.3" "Cell type enhanced" "Detected in many" "Breast lactating cells: 804.5;Conjunctival goblet cells: 908.7;Early spermatids: 803.8;Epididymal principal cells: 1534.1;Esophageal apical cells: 3054.5;Respiratory deuterosomal cells: 824.1;Salivary acinar cells: 885.0;Syncytiotrophoblasts: 1906.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Exocrine glandular cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008395, CAB015931, CAB079781" Enhanced Supported Enhanced "Golgi apparatus" "Secreted to blood" Other NA NA 1250000 830000 "Cluster 30: Non-specific - DNA binding" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 36: Choroid plexus - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 8: Non-specific - Secretory pathway" 13 "Golgi apparatus" "CAB015931: , CAB079781: , HPA008395: " "unprognostic (1.26e-1)" "unprognostic (1.47e-1)" "unprognostic (1.94e-1)" "unprognostic (1.36e-1)" "unprognostic (1.47e-1)" "unprognostic (1.01e-1)" "unprognostic (2.35e-2)" "potential prognostic unfavorable (2.72e-5)" "unprognostic (5.82e-2)" "unprognostic (6.09e-2)" "potential prognostic favorable (5.92e-4)" "unprognostic (7.45e-3)" "unprognostic (1.60e-3)" "unprognostic (3.28e-3)" "unprognostic (1.21e-3)" "unprognostic (2.29e-2)" "unprognostic (8.34e-2)" "unprognostic (9.23e-3)" "unprognostic (2.36e-1)" "unprognostic (1.80e-3)" "unprognostic (3.76e-2)" "unprognostic (1.91e-1)" "unprognostic (8.39e-2)" "unprognostic (1.75e-1)" "unprognostic (2.42e-1)" "unprognostic (2.16e-2)" "unprognostic (7.15e-2)" "unprognostic (4.17e-1)" "unprognostic (8.90e-2)" "unprognostic (7.37e-3)" "unprognostic (1.50e-1)" NUCKS1 NUCKS ENSG00000069275 "Nuclear casein kinase and cyclin dependent kinase substrate 1" Q9H1E3 1 205712822-205750182 "Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Prostate - Fibroblasts, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062351, HPA063843" Supported Supported Nucleoplasm,Nucleoli No No 140000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 27: Non-specific - Cell proliferation" 118 Nucleoplasm Nucleoli "HPA062351: , HPA063843: " "unprognostic (1.36e-1)" "unprognostic (1.51e-2)" "unprognostic (3.62e-1)" "unprognostic (1.02e-1)" "unprognostic (1.96e-2)" "unprognostic (9.99e-2)" "unprognostic (1.32e-1)" "unprognostic (3.27e-1)" "unprognostic (3.24e-1)" "unprognostic (3.28e-2)" "potential prognostic favorable (6.84e-6)" "unprognostic (1.77e-2)" "unprognostic (1.42e-2)" "unprognostic (4.33e-2)" "unprognostic (2.94e-3)" "unprognostic (2.42e-2)" "unprognostic (3.34e-3)" "unprognostic (9.72e-2)" "unprognostic (2.71e-1)" "unprognostic (1.76e-1)" "potential prognostic unfavorable (2.07e-4)" "unprognostic (1.18e-3)" "unprognostic (3.41e-1)" "unprognostic (2.64e-1)" "unprognostic (1.05e-2)" "unprognostic (2.21e-2)" "unprognostic (7.97e-3)" "unprognostic (1.82e-2)" "unprognostic (2.78e-1)" "unprognostic (1.81e-2)" "unprognostic (2.57e-1)" NUDC ENSG00000090273 "Nuclear distribution C, dynein complex regulator" Q9Y266 1 26900238-26946871 "Essential proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial ciliated cells: 487.4;Epididymal efferent duct ciliated cells: 518.3;Fallopian tube ciliated cells: 733.9;Hepatocytes: 735.4;Respiratory ciliated cells: 620.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027183, HPA028105" Enhanced Uncertain Cytosol NA NA 380000 "Cluster 41: Basophils - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 107: Ciliated cells - Cilia assembly & function" 60 Cytosol "HPA027183: , HPA028105: " "unprognostic (1.76e-2)" "unprognostic (9.85e-2)" "unprognostic (2.73e-1)" "unprognostic (1.47e-1)" "unprognostic (7.94e-2)" "unprognostic (2.86e-1)" "unprognostic (8.63e-2)" "unprognostic (1.02e-1)" "unprognostic (9.10e-2)" "potential prognostic unfavorable (8.16e-4)" "unprognostic (5.94e-2)" "unprognostic (1.13e-2)" "unprognostic (6.24e-2)" "validated prognostic unfavorable (9.27e-8)" "validated prognostic unfavorable (2.78e-4)" "unprognostic (2.45e-1)" "unprognostic (3.83e-3)" "unprognostic (6.71e-2)" "unprognostic (1.34e-1)" "unprognostic (8.13e-2)" "unprognostic (2.14e-1)" "unprognostic (2.16e-1)" "unprognostic (1.31e-1)" "unprognostic (1.34e-1)" "unprognostic (1.47e-1)" "unprognostic (2.41e-2)" "unprognostic (4.51e-2)" "unprognostic (2.59e-2)" "unprognostic (1.08e-1)" "unprognostic (1.47e-1)" "unprognostic (4.35e-3)" NUDCD1 "CML66, FLJ14991" ENSG00000120526 "NudC domain containing 1" Q96RS6 8 109240919-109334121 "Predicted intracellular proteins" Immunity "Tumor antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 146.3;Podocytes: 108.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023183 Uncertain Supported Nucleoplasm,Cytosol NA NA 11000 "Cluster 33: Non-specific - ATP binding" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 40: Non-specific - Unknown function" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 40 Nucleoplasm Cytosol "HPA023183: " "unprognostic (1.29e-1)" "unprognostic (8.62e-3)" "unprognostic (1.05e-1)" "unprognostic (2.86e-2)" "unprognostic (3.31e-1)" "unprognostic (5.34e-2)" "unprognostic (7.69e-2)" "unprognostic (1.50e-2)" "unprognostic (2.14e-2)" "potential prognostic unfavorable (3.48e-6)" "unprognostic (2.71e-3)" "unprognostic (1.27e-1)" "unprognostic (7.92e-3)" "validated prognostic unfavorable (3.51e-7)" "validated prognostic unfavorable (4.04e-4)" "potential prognostic unfavorable (6.60e-4)" "unprognostic (1.99e-2)" "unprognostic (1.33e-1)" "unprognostic (1.13e-1)" "unprognostic (3.15e-1)" "unprognostic (6.10e-3)" "unprognostic (2.04e-2)" "potential prognostic unfavorable (6.90e-4)" "unprognostic (2.46e-2)" "unprognostic (2.02e-1)" "unprognostic (5.80e-2)" "unprognostic (1.20e-1)" "unprognostic (2.18e-1)" "unprognostic (2.53e-1)" "unprognostic (2.42e-1)" "unprognostic (7.97e-2)" NUDCD2 "DKFZp686E10109, NudCL2" ENSG00000170584 "NudC domain containing 2" Q8WVJ2 5 163446526-163460102 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037384, HPA037385" Uncertain Supported "Microtubules,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes NA 18000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 97: Non-specific - Cellular respiration" 22 Microtubules "Cytokinetic bridge, Mitotic spindle, Cytosol" "HPA037384: , HPA037385: " "unprognostic (4.84e-2)" "unprognostic (7.25e-2)" "unprognostic (1.51e-1)" "unprognostic (7.14e-2)" "unprognostic (2.17e-1)" "unprognostic (9.64e-2)" "unprognostic (2.85e-2)" "unprognostic (2.12e-1)" "unprognostic (4.46e-3)" "potential prognostic unfavorable (5.97e-5)" "potential prognostic favorable (5.47e-6)" "unprognostic (2.81e-2)" "unprognostic (3.28e-1)" "unprognostic (8.75e-2)" "unprognostic (1.44e-2)" "unprognostic (5.04e-3)" "unprognostic (2.41e-2)" "unprognostic (3.23e-1)" "unprognostic (6.14e-2)" "unprognostic (3.25e-1)" "unprognostic (5.51e-2)" "unprognostic (2.35e-1)" "unprognostic (8.02e-2)" "unprognostic (1.66e-1)" "unprognostic (2.81e-3)" "unprognostic (4.86e-2)" "unprognostic (2.44e-1)" "unprognostic (1.35e-1)" "unprognostic (6.25e-2)" "unprognostic (5.20e-2)" "unprognostic (2.14e-1)" NUDCD3 "KIAA1068, NudCL" ENSG00000015676 "NudC domain containing 3" Q8IVD9 7 44379119-44490658 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019136, HPA019528, HPA019529" Enhanced Approved "Plasma membrane,Primary cilium,Primary cilium tip,Cytosol,Principal piece" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 33: Neurons - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 59 "Plasma membrane, Cytosol" "Primary cilium, Primary cilium tip, Principal piece" "HPA019136: , HPA019528: , HPA019529: " "unprognostic (1.01e-1)" "unprognostic (7.03e-2)" "unprognostic (8.87e-3)" "unprognostic (1.35e-1)" "unprognostic (3.20e-2)" "unprognostic (6.39e-2)" "unprognostic (5.96e-2)" "unprognostic (4.04e-2)" "unprognostic (2.15e-1)" "unprognostic (2.85e-1)" "validated prognostic favorable (1.49e-4)" "validated prognostic favorable (2.66e-4)" "potential prognostic favorable (3.15e-4)" "unprognostic (1.08e-1)" "unprognostic (7.64e-3)" "unprognostic (3.33e-2)" "unprognostic (9.04e-2)" "unprognostic (1.34e-2)" "unprognostic (9.18e-2)" "unprognostic (5.18e-2)" "unprognostic (1.86e-1)" "unprognostic (1.21e-2)" "unprognostic (5.71e-2)" "unprognostic (3.11e-1)" "unprognostic (3.68e-1)" "unprognostic (8.09e-2)" "unprognostic (1.48e-1)" "unprognostic (1.27e-1)" "unprognostic (1.02e-2)" "unprognostic (3.51e-2)" "unprognostic (8.28e-2)" NUDT1 MTH1 ENSG00000106268 "Nudix hydrolase 1" P36639 7 2242226-2251146 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Hydrolase, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 73.1" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 114.2;Esophageal basal cells: 175.1;Hofbauer cells: 125.0;Late primary spermatocytes: 105.8;Late spermatids: 167.4;Megakaryocyte progenitors: 112.0;Megakaryocytes: 340.0;Monocyte progenitors: 123.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Kidney - Fibroblasts, Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012636 Approved Supported Cytosol No No 52000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 7 Cytosol "HPA012636: " "unprognostic (1.26e-1)" "unprognostic (3.80e-2)" "unprognostic (3.33e-1)" "unprognostic (1.11e-1)" "potential prognostic unfavorable (8.07e-5)" "unprognostic (1.18e-1)" "potential prognostic unfavorable (9.91e-4)" "unprognostic (3.53e-1)" "unprognostic (2.27e-1)" "unprognostic (1.34e-3)" "validated prognostic unfavorable (3.45e-6)" "validated prognostic unfavorable (7.31e-6)" "unprognostic (1.27e-1)" "validated prognostic unfavorable (3.28e-4)" "validated prognostic unfavorable (8.07e-8)" "validated prognostic unfavorable (6.28e-4)" "validated prognostic unfavorable (6.07e-4)" "unprognostic (3.77e-2)" "unprognostic (5.14e-2)" "unprognostic (5.86e-2)" "unprognostic (5.03e-2)" "unprognostic (4.85e-2)" "unprognostic (1.21e-1)" "unprognostic (1.91e-1)" "unprognostic (1.08e-1)" "unprognostic (1.30e-1)" "unprognostic (7.92e-2)" "unprognostic (9.84e-2)" "unprognostic (8.85e-2)" "unprognostic (1.54e-2)" "unprognostic (9.13e-2)" NUDT10 "DIPP3a, hDIPP3alpha" ENSG00000122824 "Nudix hydrolase 10" Q8NFP7 X 51332231-51337525 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 17.0;testis: 24.6" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 6.9;Differentiating spermatogonia: 7.0;Epididymal basal cells: 29.9;Granulosa cells: 10.5;Late spermatids: 8.4;Other brain neurons: 8.3;Ovarian stromal cells: 21.4;Peritubular myoid cells: 26.0;Sertoli cells: 30.6;Undifferentiated spermatogonia: 7.2" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Glioblastoma Multiforme (TCGA): 9.2;Prostate Adenocarcinoma (TCGA): 8.8;Testicular Germ Cell Tumor (TCGA): 13.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Bone cancer: 6.2;Neuroblastoma: 7.6;testis cancer: 4.7" "Lung - Fibroblasts_2, Prostate - Fibroblasts, Skin - Outer root sheath cells, Spleen - Fibroblasts_2, Testis - Sertoli cells" "HPA047027, HPA057684" Approved Approved Cytosol NA NA "Cluster 65: Brain - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 94: Gonadal somatic cells - Mixed function" 8 Cytosol "HPA047027: , HPA057684: " "unprognostic (5.87e-2)" "unprognostic (1.89e-2)" "unprognostic (1.87e-1)" "unprognostic (2.25e-3)" "unprognostic (1.09e-2)" "unprognostic (4.31e-2)" "unprognostic (1.16e-1)" "unprognostic (2.97e-2)" "unprognostic (2.11e-2)" "unprognostic (1.84e-1)" "unprognostic (1.17e-1)" "unprognostic (1.22e-2)" "unprognostic (3.03e-1)" NUDT11 "DIPP3b, FLJ10628, hDIPP3beta" ENSG00000196368 "Nudix hydrolase 11" Q96G61 X 51490011-51496592 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.0;testis: 33.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 12.7;Breast myoepithelial cells: 14.6;Decidual stromal cells: 19.4;Differentiating spermatogonia: 12.4;Epididymal basal cells: 26.6;Late primary spermatocytes: 14.9;Late spermatids: 18.9;Oocytes: 13.8;Other brain neurons: 16.1;Ovarian stromal cells: 19.2;Pancreatic acinar cells: 13.0;Peritubular myoid cells: 15.1;Pituicytes/FSCs: 25.4;Sertoli cells: 50.5;Smooth muscle cells: 12.6;Undifferentiated spermatogonia: 27.8" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 20.6;Testicular Germ Cell Tumor (TCGA): 25.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.2" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Bone cancer: 37.7;Neuroblastoma: 27.2" "Adipose subcutaneous - Adipose progenitor cells, Breast - Breast myoepithelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047027, HPA057684" Approved Supported Cytosol NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 1 Cytosol "HPA047027: , HPA057684: " "unprognostic (4.48e-1)" "unprognostic (1.63e-1)" "unprognostic (2.95e-1)" "unprognostic (1.75e-1)" "unprognostic (2.89e-2)" "potential prognostic favorable (1.55e-4)" "unprognostic (4.42e-3)" "unprognostic (1.45e-2)" "unprognostic (1.76e-3)" "unprognostic (2.68e-1)" "unprognostic (1.00e-1)" "unprognostic (1.83e-1)" "unprognostic (1.76e-1)" "unprognostic (1.03e-2)" "unprognostic (1.98e-1)" "unprognostic (6.08e-2)" NUDT12 DKFZP761I172 ENSG00000112874 "Nudix hydrolase 12" Q9BQG2 5 103548855-103562790 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045449 Supported NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 8 "HPA045449: " "unprognostic (2.26e-1)" "unprognostic (6.36e-2)" "unprognostic (3.31e-1)" "unprognostic (3.37e-2)" "unprognostic (1.09e-1)" "unprognostic (5.32e-2)" "unprognostic (1.86e-1)" "unprognostic (1.13e-2)" "unprognostic (1.31e-1)" "unprognostic (8.14e-2)" "potential prognostic favorable (5.73e-9)" "unprognostic (1.61e-2)" "unprognostic (1.67e-1)" "unprognostic (1.24e-1)" "unprognostic (5.69e-2)" "unprognostic (1.66e-1)" "unprognostic (1.69e-1)" "unprognostic (1.64e-1)" "unprognostic (5.88e-2)" "unprognostic (2.04e-2)" "unprognostic (2.55e-3)" "unprognostic (9.53e-2)" "unprognostic (1.17e-1)" "unprognostic (2.20e-1)" "unprognostic (1.59e-2)" "unprognostic (7.71e-2)" "unprognostic (1.46e-1)" "unprognostic (1.06e-1)" "unprognostic (7.96e-2)" "unprognostic (8.17e-2)" "unprognostic (5.10e-2)" NUDT13 DKFZp586P2219 ENSG00000166321 "Nudix hydrolase 13" Q86X67 10 73110375-73131828 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 40.2;Cardiomyocytes: 154.4;Epicardial cells: 222.9;Myonuclei: 70.6;Thymic myoid cells: 43.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040636 Approved NA No "Cluster 23: B-cells - Immunoglobulins" "Cluster 76: Non-specific - Metabolism" "Cluster 15: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" "HPA040636: " "unprognostic (6.59e-3)" "unprognostic (7.27e-3)" "unprognostic (5.83e-3)" "unprognostic (6.73e-2)" "unprognostic (2.92e-3)" "unprognostic (9.10e-2)" "unprognostic (1.44e-1)" "unprognostic (1.99e-1)" "unprognostic (9.23e-3)" "unprognostic (6.07e-2)" "unprognostic (6.61e-3)" "unprognostic (4.10e-1)" "unprognostic (4.47e-3)" "unprognostic (8.71e-3)" "unprognostic (2.38e-2)" "unprognostic (3.25e-3)" "unprognostic (1.65e-1)" "unprognostic (4.33e-2)" "unprognostic (1.20e-1)" "unprognostic (2.69e-1)" "unprognostic (1.06e-1)" "unprognostic (2.02e-1)" "unprognostic (1.04e-2)" "unprognostic (3.79e-2)" "unprognostic (9.90e-3)" "unprognostic (4.14e-1)" "unprognostic (2.29e-1)" "unprognostic (1.49e-1)" "unprognostic (1.96e-1)" "unprognostic (1.46e-2)" "unprognostic (1.06e-1)" NUDT14 UGPP ENSG00000183828 "Nudix hydrolase 14" O95848 14 105172938-105181323 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 58.8;Hofbauer cells: 51.1;Parietal cells: 38.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pituitary gland - Corticotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046755, HPA058759" Approved Approved Nucleoli,Microtubules NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 9 Microtubules Nucleoli "HPA046755: , HPA058759: " "unprognostic (5.50e-3)" "unprognostic (9.15e-3)" "unprognostic (8.26e-2)" "unprognostic (2.90e-2)" "unprognostic (1.66e-1)" "unprognostic (1.74e-1)" "unprognostic (9.61e-2)" "unprognostic (4.18e-1)" "unprognostic (1.85e-1)" "unprognostic (1.56e-1)" "potential prognostic favorable (2.09e-4)" "unprognostic (2.61e-1)" "unprognostic (2.89e-2)" "unprognostic (8.58e-3)" "unprognostic (9.36e-3)" "unprognostic (2.24e-2)" "unprognostic (1.43e-1)" "unprognostic (2.30e-1)" "unprognostic (3.81e-2)" "unprognostic (3.04e-2)" "unprognostic (4.16e-2)" "unprognostic (1.93e-3)" "unprognostic (1.08e-1)" "unprognostic (2.21e-1)" "unprognostic (1.10e-1)" "unprognostic (2.45e-1)" "unprognostic (1.12e-1)" "unprognostic (1.08e-1)" "unprognostic (1.88e-1)" "unprognostic (4.85e-3)" "unprognostic (9.34e-3)" NUDT15 "FLJ10956, MTH2" ENSG00000136159 "Nudix hydrolase 15" Q9NV35 13 48037726-48047221 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 84.9;Extravillous trophoblasts: 98.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038968, HPA038969" Approved Supported Nucleoplasm Yes No "Cluster 33: Non-specific - ATP binding" "Cluster 76: Non-specific - Metabolism" "Cluster 16: Non-specific - Transcription" "Cluster 19: Non-specific - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 1 Nucleoplasm "HPA038968: , HPA038969: " "unprognostic (2.43e-1)" "unprognostic (7.74e-3)" "unprognostic (1.90e-1)" "potential prognostic unfavorable (2.90e-4)" "unprognostic (1.50e-1)" "unprognostic (1.82e-1)" "unprognostic (7.11e-2)" "unprognostic (1.01e-1)" "unprognostic (2.15e-3)" "unprognostic (2.82e-3)" "potential prognostic favorable (5.56e-6)" "unprognostic (2.80e-3)" "unprognostic (4.24e-2)" "unprognostic (5.24e-3)" "potential prognostic unfavorable (4.35e-6)" "unprognostic (1.00e-3)" "unprognostic (3.74e-3)" "unprognostic (3.50e-1)" "unprognostic (8.29e-2)" "unprognostic (1.31e-1)" "unprognostic (9.84e-2)" "unprognostic (2.43e-2)" "unprognostic (1.00e-2)" "unprognostic (1.33e-1)" "unprognostic (2.67e-1)" "unprognostic (2.29e-1)" "potential prognostic unfavorable (9.20e-5)" "unprognostic (1.30e-1)" "unprognostic (3.72e-1)" "unprognostic (1.95e-1)" "unprognostic (2.32e-1)" NUDT16 FLJ31265 ENSG00000198585 "Nudix hydrolase 16" Q96DE0 3 131381671-131388830 "Enzymes, Predicted intracellular proteins" "Nucleotide metabolism" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 159.7;Enterocytes: 307.1;Hepatocytes: 113.5;Kupffer cells: 224.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 41.7;eosinophil: 47.1;intermediate monocyte: 54.6;myeloid DC: 32.5;neutrophil: 34.1;non-classical monocyte: 63.7" "Group enriched" "Detected in all" 4 "dendritic cells: 32.5;granulocytes: 47.1;monocytes: 63.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA060452, HPA062492" Uncertain Supported Nucleoplasm,Nucleoli NA NA 27000 "Cluster 25: Non-specific - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 4 "Nucleoplasm, Nucleoli" "HPA060452: , HPA062492: " "unprognostic (3.27e-1)" "unprognostic (5.50e-2)" "unprognostic (1.95e-2)" "unprognostic (4.40e-2)" "unprognostic (2.55e-1)" "unprognostic (3.94e-1)" "unprognostic (6.37e-2)" "potential prognostic unfavorable (4.35e-5)" "unprognostic (1.16e-1)" "unprognostic (7.11e-3)" "potential prognostic favorable (1.72e-4)" "unprognostic (2.44e-2)" "potential prognostic favorable (1.44e-4)" "potential prognostic unfavorable (5.21e-4)" "unprognostic (1.95e-3)" "unprognostic (3.88e-2)" "unprognostic (1.43e-1)" "unprognostic (2.77e-1)" "unprognostic (1.43e-2)" "unprognostic (2.22e-1)" "unprognostic (6.38e-3)" "unprognostic (1.99e-1)" "unprognostic (6.83e-2)" "unprognostic (2.32e-1)" "potential prognostic favorable (2.98e-4)" "unprognostic (1.03e-2)" "unprognostic (3.83e-2)" "unprognostic (7.38e-2)" "unprognostic (3.82e-1)" "unprognostic (5.52e-3)" "unprognostic (2.16e-1)" NUDT16L1 "SDOS, TIRR" ENSG00000168101 "Nudix hydrolase 16 like 1" Q9BRJ7 16 4693562-4695859 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 122.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044186, HPA063605" Approved NA No "Cluster 3: Non-specific - Nuclear processes" "Cluster 70: Non-specific - Protein processing" "Cluster 27: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 11: Muller glia cells - Retinal homeostasis" 24 "HPA044186: , HPA063605: " "unprognostic (8.55e-2)" "unprognostic (5.84e-2)" "unprognostic (1.10e-1)" "unprognostic (7.17e-2)" "unprognostic (1.09e-1)" "unprognostic (4.49e-3)" "unprognostic (2.56e-1)" "unprognostic (3.88e-1)" "unprognostic (1.44e-2)" "unprognostic (2.40e-2)" "potential prognostic favorable (2.20e-4)" "unprognostic (2.96e-1)" "unprognostic (1.09e-3)" "unprognostic (1.48e-1)" "potential prognostic unfavorable (9.91e-5)" "unprognostic (7.52e-3)" "unprognostic (2.80e-1)" "unprognostic (8.25e-2)" "unprognostic (8.46e-2)" "unprognostic (9.85e-2)" "unprognostic (2.76e-1)" "unprognostic (9.50e-3)" "unprognostic (8.47e-2)" "unprognostic (2.32e-2)" "unprognostic (1.62e-2)" "unprognostic (2.19e-1)" "unprognostic (6.05e-2)" "unprognostic (2.47e-1)" "unprognostic (1.81e-1)" "unprognostic (8.43e-2)" "unprognostic (1.06e-1)" NUDT17 FLJ34433 ENSG00000186364 "Nudix hydrolase 17" P0C025 1 145845630-145848954 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 10.6;Differentiating spermatogonia: 18.2;Early primary spermatocytes: 12.3;Epicardial cells: 11.4;Hepatic stellate cells: 12.9;Oocytes: 13.8;pDCs: 21.7" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Uterine Corpus Endometrial Carcinoma (TCGA): 22.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "basophil: 8.4;eosinophil: 17.5;plasmacytoid DC: 26.6" "Group enriched" "Detected in many" 9 "dendritic cells: 26.6;granulocytes: 17.5" "Low cancer specificity" "Detected in all" "Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030145, HPA049649" Approved Approved Nucleoplasm NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 15: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" Nucleoplasm "HPA030145: , HPA049649: " "unprognostic (1.29e-2)" "unprognostic (1.71e-2)" "unprognostic (2.39e-1)" "unprognostic (3.17e-2)" "unprognostic (1.44e-2)" "unprognostic (3.08e-2)" "unprognostic (1.00e-1)" "unprognostic (1.42e-1)" "unprognostic (2.09e-2)" "unprognostic (4.03e-2)" "potential prognostic unfavorable (4.58e-9)" "unprognostic (2.56e-3)" "unprognostic (6.42e-2)" "potential prognostic unfavorable (4.42e-4)" "unprognostic (7.65e-2)" "unprognostic (1.83e-1)" "unprognostic (2.08e-1)" "unprognostic (2.20e-3)" "unprognostic (1.22e-1)" "unprognostic (3.89e-2)" "unprognostic (2.48e-1)" "unprognostic (1.10e-1)" "unprognostic (2.57e-1)" "unprognostic (3.85e-2)" "unprognostic (1.71e-1)" "unprognostic (3.61e-1)" "unprognostic (2.82e-2)" "unprognostic (2.01e-2)" "unprognostic (1.37e-1)" "unprognostic (2.08e-1)" "unprognostic (2.86e-1)" NUDT18 "FLJ22494, MTH3" ENSG00000275074 "Nudix hydrolase 18" Q6ZVK8 8 22106874-22109419 "Enzymes, Essential proteins, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 38.4;Epididymal principal cells: 33.5;Esophageal apical cells: 23.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028581, HPA030125" Approved Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 38: Sub-cortical - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 16 Nucleoplasm "Golgi apparatus" "HPA028581: , HPA030125: " "unprognostic (1.90e-1)" "unprognostic (4.07e-2)" "unprognostic (2.05e-2)" "unprognostic (2.01e-3)" "unprognostic (2.85e-3)" "unprognostic (3.33e-2)" "unprognostic (1.01e-3)" "unprognostic (5.42e-3)" "unprognostic (9.99e-3)" "potential prognostic favorable (5.58e-4)" "unprognostic (8.14e-2)" "potential prognostic favorable (8.44e-4)" "unprognostic (1.24e-1)" "unprognostic (2.53e-1)" "unprognostic (4.75e-2)" "unprognostic (9.72e-3)" "unprognostic (7.78e-3)" "unprognostic (6.63e-2)" "unprognostic (8.12e-2)" "unprognostic (1.81e-2)" "unprognostic (2.56e-1)" "unprognostic (1.15e-1)" "unprognostic (8.19e-2)" "unprognostic (8.41e-2)" "unprognostic (9.87e-3)" "unprognostic (4.62e-2)" "unprognostic (4.90e-2)" "potential prognostic favorable (8.61e-6)" NUDT19 RP2 ENSG00000213965 "Nudix hydrolase 19" A8MXV4 19 32691821-32713792 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Parietal cells: 74.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078387 Approved Vesicles,Cytosol NA No 9700 "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 4: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 11 Cytosol Vesicles "HPA078387: " "unprognostic (4.54e-2)" "unprognostic (3.87e-2)" "unprognostic (1.08e-1)" "unprognostic (7.06e-2)" "unprognostic (1.57e-2)" "unprognostic (2.51e-1)" "unprognostic (5.84e-2)" "potential prognostic unfavorable (2.22e-4)" "unprognostic (3.18e-1)" "unprognostic (1.44e-2)" "unprognostic (4.70e-3)" "unprognostic (1.01e-1)" "unprognostic (7.35e-2)" "unprognostic (1.34e-2)" "unprognostic (2.10e-2)" "unprognostic (4.53e-3)" "unprognostic (1.94e-1)" "unprognostic (1.54e-1)" "unprognostic (8.15e-2)" "unprognostic (1.13e-1)" "unprognostic (1.12e-1)" "unprognostic (3.04e-2)" "unprognostic (7.94e-3)" "unprognostic (5.78e-2)" "unprognostic (2.29e-3)" "unprognostic (1.83e-1)" "unprognostic (1.12e-1)" "unprognostic (1.24e-1)" "unprognostic (3.45e-1)" "unprognostic (1.97e-1)" "unprognostic (5.42e-2)" NUDT2 APAH1 ENSG00000164978 "Nudix hydrolase 2" P50583 9 34329506-34343711 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant, Intellectual disability, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004684, HPA044903, HPA058623, HPA067639" Uncertain Approved Nucleoplasm NA NA 27000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 54: Non-specific - Ribosome" "Cluster 27: Non-specific - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 65: Non-specific - Cell growth & division" 3 Nucleoplasm "CAB004684: , HPA044903: , HPA058623: , HPA067639: " "unprognostic (2.16e-1)" "unprognostic (1.01e-1)" "unprognostic (2.13e-1)" "unprognostic (1.37e-1)" "unprognostic (1.25e-1)" "unprognostic (5.83e-2)" "unprognostic (8.47e-2)" "unprognostic (5.31e-2)" "unprognostic (1.58e-1)" "unprognostic (3.10e-2)" "potential prognostic favorable (1.33e-4)" "unprognostic (1.99e-2)" "unprognostic (9.10e-2)" "unprognostic (7.63e-2)" "unprognostic (4.67e-2)" "unprognostic (1.48e-2)" "unprognostic (4.50e-2)" "unprognostic (6.45e-2)" "unprognostic (6.07e-3)" "unprognostic (1.36e-1)" "unprognostic (3.32e-1)" "unprognostic (3.31e-3)" "unprognostic (1.94e-1)" "unprognostic (7.62e-2)" "unprognostic (1.07e-1)" "unprognostic (1.96e-1)" "unprognostic (3.68e-2)" "unprognostic (1.08e-2)" "unprognostic (2.83e-1)" "unprognostic (1.38e-1)" "unprognostic (2.25e-3)" NUDT21 "CFIM25, CPSF5" ENSG00000167005 "Nudix hydrolase 21" O43809 16 56429133-56452199 "Essential proteins, Predicted intracellular proteins" "Differentiation, mRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019863, HPA074228" Uncertain Supported "Nuclear bodies,Centriolar satellite" NA NA 130000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 14: Neurons - Synaptic function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 15: Non-specific - Protein processing" 65 "Nuclear bodies" "Centriolar satellite" "HPA019863: , HPA074228: " "unprognostic (1.63e-2)" "unprognostic (1.99e-1)" "unprognostic (1.48e-1)" "unprognostic (1.21e-1)" "unprognostic (8.20e-3)" "unprognostic (1.11e-1)" "unprognostic (3.74e-2)" "potential prognostic favorable (6.40e-4)" "unprognostic (1.08e-2)" "unprognostic (4.31e-2)" "potential prognostic favorable (1.70e-8)" "unprognostic (6.83e-2)" "unprognostic (9.28e-2)" "potential prognostic unfavorable (4.79e-4)" "unprognostic (1.12e-2)" "unprognostic (7.20e-3)" "unprognostic (1.33e-2)" "unprognostic (1.82e-1)" "unprognostic (1.05e-1)" "unprognostic (6.24e-2)" "unprognostic (1.30e-3)" "potential prognostic unfavorable (4.12e-4)" "unprognostic (9.68e-2)" "unprognostic (2.24e-1)" "potential prognostic favorable (9.37e-4)" "unprognostic (1.47e-1)" "unprognostic (2.13e-2)" "unprognostic (1.64e-1)" "unprognostic (3.58e-2)" "unprognostic (9.99e-2)" "unprognostic (1.14e-1)" NUDT22 MGC13045 ENSG00000149761 "Nudix hydrolase 22" Q9BRQ3 11 64225941-64230686 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 133.3;Esophageal apical cells: 126.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039334, HPA053464" Approved Enhanced Nucleoplasm No No "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 67: Plasma cells - Plasma cell differentiation" 17 Nucleoplasm "HPA039334: , HPA053464: " "unprognostic (1.18e-3)" "unprognostic (1.15e-1)" "unprognostic (2.16e-2)" "unprognostic (5.90e-2)" "unprognostic (3.09e-2)" "unprognostic (3.42e-2)" "unprognostic (2.56e-2)" "unprognostic (3.47e-1)" "unprognostic (1.61e-2)" "unprognostic (1.66e-2)" "unprognostic (3.99e-1)" "unprognostic (5.08e-2)" "potential prognostic favorable (4.23e-5)" "unprognostic (4.00e-3)" "unprognostic (1.47e-1)" "unprognostic (1.73e-1)" "unprognostic (7.16e-2)" "unprognostic (2.67e-1)" "unprognostic (1.77e-1)" "unprognostic (2.45e-1)" "unprognostic (2.37e-1)" "unprognostic (1.20e-1)" "unprognostic (4.84e-2)" "unprognostic (1.90e-2)" "unprognostic (4.26e-2)" "unprognostic (2.96e-1)" "unprognostic (6.05e-2)" "unprognostic (3.87e-2)" "unprognostic (1.72e-1)" "unprognostic (7.90e-2)" "unprognostic (9.63e-3)" NUDT3 DIPP ENSG00000272325 "Nudix hydrolase 3" O95989 6 34279679-34392669 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 229.4;Bergmann glia: 217.8;Choroid plexus epithelial cells: 227.4;Microglia: 697.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047027, HPA055953" Uncertain Approved Cytosol NA NA 51000 "Cluster 29: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 28: Non-specific - Nuclear processes" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 37 Cytosol "HPA047027: , HPA055953: " "unprognostic (3.88e-3)" "unprognostic (2.64e-2)" "unprognostic (2.69e-1)" "unprognostic (4.65e-2)" "unprognostic (9.23e-2)" "unprognostic (1.12e-1)" "unprognostic (1.05e-1)" "unprognostic (2.22e-1)" "potential prognostic favorable (8.87e-4)" "unprognostic (7.14e-2)" "validated prognostic favorable (1.64e-5)" "validated prognostic favorable (1.80e-4)" "unprognostic (5.31e-2)" "unprognostic (2.43e-2)" "unprognostic (6.68e-2)" "unprognostic (6.73e-2)" "unprognostic (7.99e-2)" "unprognostic (2.16e-1)" "unprognostic (3.53e-2)" "unprognostic (1.92e-1)" "unprognostic (1.28e-2)" "unprognostic (8.68e-2)" "unprognostic (1.20e-2)" "unprognostic (3.34e-3)" "unprognostic (3.13e-2)" "unprognostic (3.64e-2)" "unprognostic (6.56e-2)" "unprognostic (1.99e-1)" "unprognostic (3.03e-1)" NUDT4 "DIPP2, DIPP2alpha, DIPP2beta, HDCMB47P, KIAA0487" ENSG00000173598 "Nudix hydrolase 4" Q9NZJ9 12 93377883-93408146 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 590.9;Pituicytes/FSCs: 252.2;Schwann cells: 237.0" "Cell type enhanced" "Detected in all" "vascular associated smooth muscle cell: 122.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary gland ductal cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "HPA017593, HPA047027, HPA057684" Approved Supported Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 53: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 4 Cytosol "HPA017593: , HPA047027: , HPA057684: " "unprognostic (1.70e-2)" "unprognostic (7.67e-3)" "unprognostic (2.56e-1)" "unprognostic (2.64e-2)" "unprognostic (3.27e-2)" "unprognostic (8.57e-2)" "unprognostic (1.06e-3)" "unprognostic (3.33e-3)" "unprognostic (1.78e-1)" "unprognostic (2.44e-1)" "validated prognostic favorable (6.30e-6)" "validated prognostic favorable (2.63e-5)" "unprognostic (1.22e-1)" "unprognostic (5.70e-2)" "unprognostic (4.00e-3)" "unprognostic (4.47e-3)" "unprognostic (9.72e-2)" "unprognostic (1.20e-1)" "unprognostic (4.89e-1)" "unprognostic (4.47e-1)" "unprognostic (3.52e-3)" "unprognostic (8.77e-2)" "unprognostic (1.01e-1)" "unprognostic (2.14e-1)" "unprognostic (9.63e-3)" "unprognostic (3.13e-2)" "unprognostic (3.43e-1)" "unprognostic (2.40e-1)" "unprognostic (3.31e-1)" "unprognostic (2.47e-1)" "unprognostic (5.92e-2)" NUDT4B NUDT4P1 ENSG00000177144 "Nudix hydrolase 4B" A0A024RBG1 1 148748774-148752415 "Enzymes, Predicted intracellular proteins" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 1.7;Loop of henle epithelial cells: 4.1;Renal collecting duct principal cells: 1.6;Renal connecting tubule cells: 1.8" "Cancer enhanced" "Detected in many" "Stomach Adenocarcinoma (TCGA): 22.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 3.3" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "HPA017593, HPA047027, HPA057684" Approved Approved Cytosol NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 53: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 1 Cytosol "HPA017593: , HPA047027: , HPA057684: " "unprognostic (2.40e-2)" "unprognostic (4.30e-2)" "unprognostic (8.13e-2)" "unprognostic (6.17e-2)" "unprognostic (5.15e-2)" "unprognostic (6.54e-2)" "unprognostic (9.44e-3)" "unprognostic (2.22e-1)" "unprognostic (4.68e-1)" "potential prognostic favorable (9.40e-6)" "unprognostic (5.09e-3)" "unprognostic (1.75e-1)" "unprognostic (8.36e-2)" "unprognostic (2.43e-1)" "unprognostic (9.20e-2)" "unprognostic (1.73e-1)" "unprognostic (6.36e-2)" "unprognostic (1.08e-2)" "unprognostic (2.10e-3)" "unprognostic (1.91e-1)" "unprognostic (7.83e-2)" "unprognostic (3.89e-3)" "unprognostic (9.01e-2)" "unprognostic (1.95e-1)" "unprognostic (1.79e-1)" "unprognostic (6.28e-2)" "unprognostic (7.15e-2)" NUDT5 "hYSAH1, YSA1H" ENSG00000165609 "Nudix hydrolase 5" Q9UKK9 10 12165330-12196144 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 230.7;Neutrophils: 491.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019827 Approved Approved "Nucleoplasm,Vesicles,Centrosome,Mid piece" NA NA 2000000 "Cluster 29: Non-specific - Unknown function" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 52: Non-specific - Mitochondria" "Cluster 24: Neutrophils - Innate immunity signal integration" 17 "Nucleoplasm, Vesicles" "Centrosome, Mid piece" "HPA019827: " "unprognostic (1.01e-1)" "unprognostic (9.13e-3)" "unprognostic (8.59e-2)" "unprognostic (3.00e-2)" "unprognostic (1.15e-1)" "unprognostic (3.67e-2)" "unprognostic (9.84e-3)" "potential prognostic favorable (1.39e-5)" "unprognostic (2.84e-2)" "unprognostic (9.37e-3)" "validated prognostic unfavorable (3.14e-5)" "validated prognostic unfavorable (4.92e-5)" "potential prognostic unfavorable (2.81e-4)" "potential prognostic unfavorable (1.44e-4)" "unprognostic (5.73e-2)" "unprognostic (2.03e-2)" "unprognostic (1.21e-1)" "unprognostic (9.77e-2)" "unprognostic (6.55e-2)" "unprognostic (4.43e-2)" "unprognostic (7.20e-2)" "unprognostic (2.15e-2)" "unprognostic (1.37e-3)" "unprognostic (5.99e-1)" "unprognostic (1.08e-1)" "unprognostic (2.97e-1)" "unprognostic (7.69e-2)" "unprognostic (3.00e-2)" "unprognostic (3.52e-1)" "unprognostic (3.72e-1)" "unprognostic (3.22e-2)" NUDT6 "FGF-AS, FGF2AS, gfg, gfg-1" ENSG00000170917 "Nudix hydrolase 6" P53370 4 122888697-122922968 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 57.5;Late primary spermatocytes: 62.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039202, HPA066115" Uncertain NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 76: Non-specific - Metabolism" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 89: Adipocytes - Lipid metabolism" 1 "HPA039202: , HPA066115: " "unprognostic (2.52e-1)" "unprognostic (1.15e-1)" "unprognostic (4.61e-2)" "unprognostic (1.17e-3)" "unprognostic (4.40e-3)" "unprognostic (2.88e-2)" "unprognostic (9.31e-3)" "unprognostic (3.15e-1)" "unprognostic (4.52e-2)" "unprognostic (6.01e-2)" "potential prognostic favorable (3.22e-6)" "unprognostic (5.58e-3)" "potential prognostic favorable (9.23e-9)" "unprognostic (3.23e-2)" "unprognostic (1.76e-2)" "unprognostic (1.04e-2)" "unprognostic (4.88e-2)" "unprognostic (8.11e-2)" "unprognostic (5.87e-2)" "unprognostic (1.90e-1)" "unprognostic (3.53e-2)" "unprognostic (1.15e-1)" "unprognostic (1.76e-1)" "unprognostic (1.84e-1)" "unprognostic (3.11e-2)" "unprognostic (2.80e-1)" "unprognostic (3.59e-1)" "unprognostic (4.13e-1)" "unprognostic (6.12e-2)" "unprognostic (7.56e-2)" "unprognostic (3.92e-2)" NUDT7 ENSG00000140876 "Nudix hydrolase 7" P0C024 16 77722492-77742260 "Predicted intracellular proteins" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 65.6" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 41.4;Hepatocytes: 53.0" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 42.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042042 Supported Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 76: Non-specific - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 97: Non-specific - Cellular respiration" "Golgi apparatus" Nucleoplasm "HPA042042: " "unprognostic (2.93e-1)" "unprognostic (1.41e-1)" "unprognostic (7.30e-2)" "unprognostic (3.17e-2)" "unprognostic (8.98e-2)" "unprognostic (2.07e-1)" "unprognostic (1.20e-1)" "unprognostic (7.25e-2)" "unprognostic (2.85e-3)" "unprognostic (2.78e-2)" "potential prognostic favorable (2.75e-10)" "unprognostic (1.53e-2)" "unprognostic (1.84e-3)" "unprognostic (2.99e-1)" "unprognostic (1.42e-3)" "unprognostic (2.09e-1)" "unprognostic (8.22e-2)" "unprognostic (2.15e-1)" "unprognostic (1.90e-1)" "unprognostic (3.24e-1)" "unprognostic (7.15e-2)" "unprognostic (1.38e-1)" "unprognostic (1.72e-1)" "unprognostic (1.74e-1)" "unprognostic (6.84e-3)" "unprognostic (5.01e-2)" "unprognostic (9.73e-2)" "unprognostic (1.81e-1)" "unprognostic (4.94e-2)" "unprognostic (2.51e-2)" "unprognostic (1.13e-1)" NUDT8 FLJ41567 ENSG00000167799 "Nudix hydrolase 8" Q8WV74 11 67627938-67629937 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 73.1" "Cell type enhanced" "Detected in many" "Breast lactating cells: 117.8;Enterocytes: 124.1;Esophageal apical cells: 290.3;Esophageal basal cells: 193.6;Esophageal suprabasal cells: 358.3;Hepatocytes: 191.8;Respiratory secretory cells: 108.3;Suprabasal keratinocytes: 121.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes" "HPA041252, HPA041466" Enhanced Approved Nucleoli,Cytosol NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 45: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 85: Squamous epithelial cells - Keratinization" 6 Nucleoli Cytosol "HPA041252: , HPA041466: " "unprognostic (3.86e-2)" "unprognostic (6.84e-3)" "unprognostic (7.95e-2)" "unprognostic (2.80e-3)" "unprognostic (6.21e-2)" "unprognostic (4.21e-2)" "unprognostic (2.73e-1)" "unprognostic (2.56e-1)" "unprognostic (9.84e-3)" "unprognostic (1.37e-1)" "unprognostic (9.88e-3)" "unprognostic (3.90e-1)" "unprognostic (2.18e-3)" "unprognostic (1.48e-1)" "unprognostic (3.20e-1)" "unprognostic (4.90e-1)" "unprognostic (3.69e-2)" "unprognostic (1.66e-2)" "unprognostic (6.66e-2)" "unprognostic (3.99e-2)" "unprognostic (1.42e-2)" "unprognostic (2.47e-2)" "potential prognostic favorable (8.42e-4)" "unprognostic (3.30e-1)" "unprognostic (1.94e-1)" "unprognostic (6.70e-2)" "unprognostic (2.38e-1)" "unprognostic (2.14e-2)" "unprognostic (1.14e-1)" "unprognostic (1.18e-1)" "unprognostic (1.02e-1)" NUDT9 MGC3037 ENSG00000170502 "Nudix hydrolase 9" Q9BW91 4 87422573-87459455 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036917, HPA044866, HPA078535" Approved Approved "Nuclear membrane,Nuclear bodies,Cell Junctions,Mitochondria" "Intracellular and membrane" Enzyme NA NA 42000 "Cluster 33: Non-specific - ATP binding" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 31: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 5 "Nuclear bodies, Mitochondria" "Nuclear membrane, Cell Junctions" "HPA036917: , HPA044866: , HPA078535: " "unprognostic (1.29e-1)" "unprognostic (1.63e-1)" "unprognostic (2.06e-1)" "unprognostic (7.95e-3)" "potential prognostic favorable (4.43e-4)" "unprognostic (1.24e-1)" "unprognostic (1.25e-1)" "unprognostic (6.98e-2)" "unprognostic (1.83e-2)" "unprognostic (5.60e-2)" "validated prognostic favorable (2.89e-9)" "validated prognostic favorable (4.98e-4)" "unprognostic (5.50e-3)" "unprognostic (5.61e-2)" "unprognostic (4.00e-3)" "unprognostic (1.23e-1)" "unprognostic (1.94e-1)" "unprognostic (5.59e-2)" "unprognostic (1.36e-1)" "unprognostic (3.96e-2)" "unprognostic (3.37e-2)" "unprognostic (3.20e-1)" "unprognostic (9.64e-3)" "unprognostic (4.85e-1)" "unprognostic (1.90e-2)" "unprognostic (1.13e-1)" "unprognostic (5.15e-2)" "unprognostic (7.89e-2)" "unprognostic (1.54e-1)" "unprognostic (1.68e-1)" "unprognostic (8.21e-2)" NUF2 "CDCA1, CT106, NUF2R" ENSG00000143228 "NUF2 component of NDC80 kinetochore complex" Q9BZD4 1 163266576-163355764 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 26.8;lymphoid tissue: 24.2;testis: 50.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 194.3;Differentiating spermatogonia: 64.4;Early primary spermatocytes: 159.2;Epicardial cells: 113.7;Erythrocyte progenitors: 86.3;Late primary spermatocytes: 308.2;Monocyte progenitors: 89.6;Oocytes: 82.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 4.3" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA059692, HPA076604" Supported Nucleoplasm,Kinetochore,Cytosol Yes Yes "Cluster 5: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 11: White matter - Signal transduction" "Cluster 45: Non-specific - Nuclear processes" "Cluster 27: Non-specific - Cell proliferation" 44 Nucleoplasm "Kinetochore, Cytosol" "HPA059692: , HPA076604: " "unprognostic (4.21e-2)" "unprognostic (9.25e-2)" "unprognostic (4.64e-2)" "unprognostic (2.42e-1)" "unprognostic (2.59e-1)" "unprognostic (6.94e-2)" "unprognostic (4.23e-2)" "unprognostic (2.08e-3)" "unprognostic (2.33e-2)" "validated prognostic unfavorable (5.80e-13)" "validated prognostic unfavorable (7.05e-6)" "potential prognostic unfavorable (1.54e-8)" "validated prognostic unfavorable (2.44e-6)" "validated prognostic unfavorable (1.81e-6)" "potential prognostic unfavorable (7.33e-5)" "unprognostic (8.24e-3)" "unprognostic (3.69e-2)" "unprognostic (3.22e-2)" "unprognostic (3.91e-1)" "unprognostic (8.65e-2)" "unprognostic (1.08e-3)" "potential prognostic unfavorable (5.05e-4)" "unprognostic (3.79e-2)" "unprognostic (3.81e-1)" "unprognostic (1.17e-1)" "unprognostic (5.40e-3)" "unprognostic (8.31e-2)" "unprognostic (6.41e-2)" "unprognostic (1.03e-2)" NUFIP1 "NUFIP, Rsa1" ENSG00000083635 "Nuclear FMR1 interacting protein 1" Q9UHK0 13 44939249-44989471 "Essential proteins, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 110.9;Oocytes: 69.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029958, HPA029959" Approved Enhanced Nucleoplasm,Nucleoli Yes No "Cluster 18: Non-specific - Translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 26 Nucleoplasm Nucleoli "HPA029958: , HPA029959: " "unprognostic (1.22e-1)" "unprognostic (1.69e-1)" "unprognostic (5.57e-2)" "unprognostic (3.03e-3)" "unprognostic (9.61e-2)" "unprognostic (8.37e-2)" "unprognostic (6.38e-2)" "unprognostic (2.12e-2)" "unprognostic (9.03e-3)" "potential prognostic unfavorable (7.62e-5)" "potential prognostic favorable (1.41e-5)" "unprognostic (2.38e-2)" "unprognostic (3.74e-1)" "unprognostic (7.01e-2)" "potential prognostic unfavorable (6.71e-4)" "unprognostic (1.40e-2)" "potential prognostic unfavorable (4.98e-5)" "unprognostic (3.78e-2)" "unprognostic (6.02e-2)" "unprognostic (2.69e-3)" "potential prognostic unfavorable (1.54e-4)" "unprognostic (3.50e-2)" "unprognostic (8.38e-2)" "unprognostic (2.09e-2)" "unprognostic (6.86e-2)" "unprognostic (9.41e-2)" "unprognostic (8.68e-3)" "unprognostic (2.22e-1)" "unprognostic (1.17e-1)" "unprognostic (1.05e-1)" "unprognostic (1.48e-2)" NUFIP2 "182-FIP, 82-FIP, FIP-82, KIAA1321, MGC117262, NUFP2, PIG1" ENSG00000108256 "Nuclear FMR1 interacting protein 2" Q7Z417 17 29255839-29294148 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 75.4" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067443 Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 25000 "Cluster 22: Eosinophils - Transcription" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Breast cancer - Unknown function" "Cluster 20: Non-specific - Transcription regulation" 142 Nucleoplasm "Nuclear bodies, Cytosol" "HPA067443: " "unprognostic (2.24e-2)" "unprognostic (5.01e-2)" "unprognostic (1.21e-1)" "unprognostic (3.25e-3)" "unprognostic (4.39e-1)" "unprognostic (2.13e-1)" "unprognostic (1.41e-1)" "unprognostic (1.12e-1)" "unprognostic (1.21e-1)" "unprognostic (2.10e-3)" "unprognostic (3.90e-3)" "unprognostic (2.22e-1)" "unprognostic (2.57e-2)" "unprognostic (6.86e-3)" "unprognostic (1.72e-1)" "unprognostic (7.97e-2)" "unprognostic (1.58e-1)" "unprognostic (1.14e-1)" "unprognostic (8.34e-2)" "unprognostic (2.17e-3)" "unprognostic (2.37e-2)" "potential prognostic unfavorable (4.22e-4)" "unprognostic (6.13e-3)" "unprognostic (5.06e-2)" "unprognostic (4.39e-3)" "unprognostic (3.56e-2)" "unprognostic (6.43e-2)" "unprognostic (3.52e-1)" "unprognostic (1.76e-1)" "unprognostic (5.52e-2)" "unprognostic (2.02e-1)" NUGGC "C8orf80, HMFN0672, SLIP-GC" ENSG00000189233 "Nuclear GTPase, germinal center associated" Q68CJ6 8 28021964-28083936 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "liver: 19.2;lymphoid tissue: 21.4" "Group enriched" "Detected in some" 4 "Hepatocytes: 84.0;Plasma cells: 150.6;Proximal tubule cells: 54.2" "Cell type enriched" "Detected in some" 13 "leukocyte: 15.4" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 4.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 4.0" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 31 "lymphoma: 28.9;Myeloma: 17.2" "Adipose visceral - Mesothelial cells, Breast - Plasma cells, Kidney - Proximal tubular cells, Minor Salivary Gland - Plasma cells, Skin - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA024293 Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 44: Plasma cells - Antibody production & secretion" "Nuclear speckles" "Nucleoplasm, Cytosol" "HPA024293: " "unprognostic (5.88e-3)" "unprognostic (2.41e-1)" "unprognostic (1.14e-1)" "unprognostic (5.02e-3)" "unprognostic (1.91e-2)" "unprognostic (6.19e-3)" "unprognostic (1.12e-3)" "potential prognostic favorable (1.10e-4)" "unprognostic (1.75e-1)" "unprognostic (2.54e-1)" "unprognostic (3.60e-2)" "unprognostic (5.47e-2)" "unprognostic (8.58e-2)" "unprognostic (2.25e-1)" "unprognostic (4.39e-2)" "unprognostic (3.12e-1)" NUMA1 NUMA ENSG00000137497 "Nuclear mitotic apparatus protein 1" Q14980 11 72002864-72080693 "Cancer-related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019841, HPA019859, HPA029912" Enhanced Enhanced Nucleoplasm NA Yes 92000 "Cluster 24: Non-specific - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 24: Non-specific - Unknown function" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 239 Nucleoplasm "HPA019841: , HPA019859: , HPA029912: " "unprognostic (2.07e-3)" "unprognostic (1.16e-1)" "unprognostic (8.60e-2)" "unprognostic (2.40e-3)" "unprognostic (5.93e-2)" "unprognostic (2.56e-1)" "unprognostic (5.74e-2)" "unprognostic (3.36e-3)" "unprognostic (5.05e-3)" "unprognostic (1.01e-1)" "potential prognostic favorable (1.59e-8)" "unprognostic (1.95e-3)" "unprognostic (1.99e-1)" "unprognostic (9.16e-2)" "unprognostic (3.15e-1)" "unprognostic (6.01e-2)" "unprognostic (4.49e-2)" "unprognostic (5.74e-2)" "unprognostic (2.84e-3)" "unprognostic (9.77e-2)" "unprognostic (4.73e-2)" "unprognostic (1.44e-2)" "unprognostic (2.81e-2)" "unprognostic (1.19e-1)" "unprognostic (7.49e-3)" "unprognostic (1.19e-2)" "unprognostic (2.20e-1)" "unprognostic (2.24e-1)" "unprognostic (2.68e-1)" "unprognostic (2.86e-1)" "unprognostic (1.02e-1)" NUMB C14orf41 ENSG00000133961 "NUMB endocytic adaptor protein" P49757 14 73275107-73458617 "Cancer-related genes, Predicted intracellular proteins" Neurogenesis "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Neutrophils: 2516.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 292.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002874, CAB011478" Approved Uncertain "Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 24: Neutrophils - Innate immunity signal integration" 68 "Cell Junctions" "Plasma membrane, Cytosol" "CAB011478: , HPA002874: " "unprognostic (1.25e-1)" "unprognostic (2.96e-1)" "unprognostic (4.34e-2)" "unprognostic (2.37e-2)" "unprognostic (7.06e-2)" "unprognostic (4.25e-2)" "unprognostic (2.96e-1)" "unprognostic (1.02e-1)" "unprognostic (2.90e-1)" "unprognostic (7.76e-3)" "validated prognostic favorable (3.41e-7)" "validated prognostic favorable (3.44e-5)" "potential prognostic favorable (6.75e-4)" "unprognostic (1.69e-1)" "unprognostic (8.83e-3)" "unprognostic (9.25e-3)" "unprognostic (6.15e-2)" "unprognostic (1.05e-2)" "unprognostic (7.78e-2)" "unprognostic (1.09e-3)" "unprognostic (1.38e-3)" "potential prognostic unfavorable (1.06e-4)" "unprognostic (2.45e-3)" "unprognostic (2.04e-1)" "unprognostic (1.66e-1)" "unprognostic (1.23e-2)" "unprognostic (4.72e-3)" "unprognostic (7.21e-2)" "unprognostic (1.69e-1)" "unprognostic (3.08e-1)" "unprognostic (1.31e-1)" NUMBL "CAG3A, CTG3a, NUMB-R, NUMBLIKE, NUMBR, TNRC23" ENSG00000105245 "NUMB like endocytic adaptor protein" Q9Y6R0 19 40665905-40690972 "Plasma proteins, Predicted intracellular proteins" "Neurogenesis, Ubl conjugation pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Leydig cells: 60.5;Peritubular myoid cells: 55.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058251, HPA058380" Approved NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 94: Gonadal somatic cells - Mixed function" 37 "HPA058251: , HPA058380: " "unprognostic (2.83e-2)" "unprognostic (3.23e-2)" "unprognostic (9.29e-2)" "unprognostic (8.82e-2)" "potential prognostic unfavorable (7.20e-4)" "unprognostic (7.12e-3)" "unprognostic (4.55e-1)" "unprognostic (9.50e-2)" "unprognostic (2.80e-2)" "unprognostic (5.03e-3)" "validated prognostic unfavorable (4.95e-9)" "validated prognostic unfavorable (2.72e-7)" "potential prognostic unfavorable (3.57e-5)" "unprognostic (1.69e-2)" "unprognostic (2.49e-1)" "potential prognostic unfavorable (1.04e-4)" "unprognostic (1.44e-2)" "unprognostic (1.10e-1)" "unprognostic (4.98e-2)" "potential prognostic unfavorable (1.69e-4)" "unprognostic (9.29e-2)" "unprognostic (1.77e-1)" "unprognostic (2.72e-2)" "unprognostic (2.63e-2)" "unprognostic (2.80e-1)" "unprognostic (5.78e-3)" "unprognostic (4.05e-2)" "unprognostic (3.26e-2)" "unprognostic (1.26e-1)" "unprognostic (1.24e-1)" "unprognostic (1.16e-1)" NUP107 NUP84 ENSG00000111581 "Nucleoporin 107" P57740 12 68686951-68745809 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early primary spermatocytes: 194.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031679 Uncertain "Nucleoplasm,Nuclear membrane,Centrosome" NA NA 4500 "Cluster 3: Non-specific - Nuclear processes" "Cluster 39: Testis - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 27: Non-specific - Cell proliferation" 57 Nucleoplasm "Nuclear membrane, Centrosome" "HPA031679: " "unprognostic (8.21e-2)" "unprognostic (2.77e-1)" "unprognostic (1.49e-1)" "unprognostic (1.98e-1)" "unprognostic (6.85e-2)" "unprognostic (2.46e-1)" "unprognostic (3.16e-1)" "unprognostic (1.62e-2)" "unprognostic (1.55e-1)" "unprognostic (3.84e-2)" "unprognostic (5.47e-2)" "unprognostic (2.74e-1)" "unprognostic (6.15e-2)" "potential prognostic unfavorable (1.93e-6)" "unprognostic (1.44e-3)" "potential prognostic unfavorable (8.30e-4)" "unprognostic (1.88e-3)" "unprognostic (3.10e-2)" "unprognostic (7.69e-2)" "unprognostic (8.67e-2)" "unprognostic (3.19e-1)" "validated prognostic unfavorable (8.55e-4)" "validated prognostic unfavorable (3.19e-4)" "unprognostic (1.13e-3)" "unprognostic (1.86e-3)" "unprognostic (6.83e-3)" "unprognostic (4.55e-2)" "unprognostic (1.18e-1)" "unprognostic (3.61e-2)" "unprognostic (5.87e-2)" "unprognostic (1.26e-1)" NUP133 FLJ10814 ENSG00000069248 "Nucleoporin 133" Q8WUM0 1 229440259-229508341 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059767 Approved Supported "Nuclear membrane" NA NA 24000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" 63 "Nuclear membrane" "HPA059767: " "unprognostic (2.40e-1)" "unprognostic (6.49e-3)" "unprognostic (2.24e-1)" "unprognostic (5.10e-2)" "unprognostic (8.89e-2)" "unprognostic (7.86e-2)" "unprognostic (8.13e-2)" "unprognostic (1.09e-2)" "unprognostic (2.60e-1)" "unprognostic (4.77e-2)" "potential prognostic favorable (2.51e-5)" "unprognostic (6.49e-2)" "unprognostic (2.81e-2)" "unprognostic (2.46e-2)" "unprognostic (1.53e-1)" "unprognostic (2.34e-1)" "unprognostic (1.02e-2)" "unprognostic (1.21e-1)" "unprognostic (2.67e-1)" "unprognostic (8.01e-2)" "potential prognostic unfavorable (9.10e-4)" "unprognostic (1.03e-1)" "unprognostic (2.28e-2)" "unprognostic (2.09e-1)" "potential prognostic favorable (3.71e-4)" "unprognostic (6.85e-2)" "unprognostic (1.43e-1)" "unprognostic (1.37e-1)" "unprognostic (9.20e-2)" "unprognostic (7.72e-3)" "unprognostic (1.50e-1)" NUP153 HNUP153 ENSG00000124789 "Nucleoporin 153" P49790 6 17615035-17706925 "Essential proteins, Metabolic proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, mRNA transport, Protein transport, Translocation, Transport, Viral penetration into host nucleus, Virus entry into host cell" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 396.6;Neutrophils: 378.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027896, HPA027897, HPA027898, HPA027899" Supported Enhanced "Nuclear membrane" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 87 "Nuclear membrane" "HPA027896: , HPA027897: , HPA027898: , HPA027899: " "unprognostic (6.94e-2)" "unprognostic (1.29e-1)" "unprognostic (6.37e-2)" "unprognostic (3.63e-1)" "unprognostic (2.13e-1)" "unprognostic (2.02e-1)" "unprognostic (2.09e-1)" "unprognostic (2.87e-1)" "unprognostic (2.72e-2)" "unprognostic (6.14e-2)" "potential prognostic favorable (1.53e-5)" "unprognostic (1.36e-3)" "unprognostic (6.87e-2)" "unprognostic (1.55e-2)" "unprognostic (2.92e-2)" "unprognostic (9.12e-2)" "unprognostic (1.49e-2)" "unprognostic (3.11e-1)" "unprognostic (1.67e-1)" "unprognostic (8.52e-2)" "unprognostic (3.10e-1)" "unprognostic (7.80e-2)" "unprognostic (7.86e-2)" "unprognostic (8.34e-2)" "unprognostic (1.78e-3)" "unprognostic (2.91e-2)" "unprognostic (2.14e-2)" "unprognostic (2.32e-2)" "unprognostic (3.15e-1)" "unprognostic (7.95e-3)" "unprognostic (2.29e-1)" NUP155 "KIAA0791, N155" ENSG00000113569 "Nucleoporin 155" O75694 5 37288137-37371106 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Atrial fibrillation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "testis: 66.2" "Cell type enhanced" "Detected in many" "Late spermatids: 192.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037775 Enhanced Enhanced "Nuclear membrane" NA NA 44000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 57: Testis - Spermatogenesis" "Cluster 55: Non-specific - Transcription" "Cluster 29: Non-specific - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 56 "Nuclear membrane" "HPA037775: " "unprognostic (2.40e-1)" "unprognostic (2.54e-2)" "unprognostic (6.37e-3)" "unprognostic (2.48e-2)" "unprognostic (3.55e-2)" "unprognostic (9.21e-2)" "unprognostic (1.59e-1)" "unprognostic (3.23e-2)" "unprognostic (1.09e-1)" "potential prognostic unfavorable (3.61e-4)" "potential prognostic favorable (2.62e-4)" "unprognostic (2.39e-2)" "unprognostic (2.18e-1)" "potential prognostic unfavorable (6.12e-4)" "unprognostic (2.50e-3)" "unprognostic (7.15e-3)" "unprognostic (3.25e-3)" "unprognostic (1.55e-1)" "unprognostic (2.72e-2)" "unprognostic (1.21e-1)" "unprognostic (1.93e-1)" "unprognostic (2.17e-3)" "potential prognostic unfavorable (9.77e-4)" "unprognostic (1.36e-1)" "unprognostic (1.06e-2)" "unprognostic (4.69e-2)" "unprognostic (7.09e-2)" "unprognostic (6.98e-2)" "unprognostic (3.65e-1)" "unprognostic (8.63e-3)" "unprognostic (9.48e-2)" NUP160 "FLJ22583, KIAA0197" ENSG00000030066 "Nucleoporin 160" Q12769 11 47778087-47848555 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 58.2;Bergmann glia: 72.8;Brain excitatory neurons: 55.6;Brain inhibitory neurons: 54.6;Choroid plexus epithelial cells: 101.0;Distal convoluted tubule cells: 95.2;Ependymal cells: 59.5;Loop of henle epithelial cells: 74.8;Microglia: 62.9;Oligodendrocyte progenitor cells: 89.2;Oligodendrocytes: 74.5;Other brain neurons: 47.0;Papillary tip epithelial cells: 60.2;Podocytes: 58.1;Proximal tubule cells: 64.4;Renal collecting duct intercalated cells: 117.4;Renal collecting duct principal cells: 59.9;Renal connecting tubule cells: 68.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 39000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 102: Non-specific - Mixed function" 38 "unprognostic (3.05e-1)" "unprognostic (1.07e-1)" "unprognostic (2.11e-2)" "unprognostic (2.68e-2)" "unprognostic (2.56e-1)" "unprognostic (3.82e-2)" "unprognostic (1.50e-1)" "unprognostic (9.75e-2)" "unprognostic (1.94e-1)" "unprognostic (6.52e-3)" "validated prognostic favorable (3.47e-6)" "validated prognostic favorable (8.03e-4)" "unprognostic (5.76e-3)" "unprognostic (2.13e-3)" "unprognostic (9.38e-2)" "unprognostic (1.80e-1)" "potential prognostic unfavorable (1.59e-6)" "unprognostic (1.64e-1)" "unprognostic (3.16e-1)" "unprognostic (1.10e-1)" "unprognostic (8.97e-3)" "unprognostic (1.25e-2)" "potential prognostic unfavorable (2.23e-6)" "unprognostic (1.33e-2)" "unprognostic (2.62e-3)" "unprognostic (4.99e-2)" "unprognostic (3.05e-2)" "unprognostic (1.37e-1)" "unprognostic (1.68e-1)" "unprognostic (2.32e-1)" "unprognostic (2.54e-1)" NUP188 KIAA0169 ENSG00000095319 "Nucleoporin 188" Q5SRE5 9 128947699-129007096 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Cataract, Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epicardial cells: 81.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA061750, HPA063942" Approved Approved Nucleoplasm,Nucleoli,Cytosol No No 6700 "Cluster 33: Non-specific - ATP binding" "Cluster 39: Testis - Nuclear processes" "Cluster 25: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 103: Non-specific - Basic cellular processes" 15 Nucleoplasm "Nucleoli, Cytosol" "HPA061750: , HPA063942: " "unprognostic (8.42e-3)" "unprognostic (1.02e-1)" "unprognostic (2.39e-1)" "unprognostic (6.50e-2)" "unprognostic (7.76e-2)" "unprognostic (2.05e-2)" "unprognostic (1.09e-1)" "unprognostic (1.53e-2)" "unprognostic (7.68e-2)" "unprognostic (2.65e-3)" "potential prognostic favorable (6.59e-4)" "unprognostic (5.04e-3)" "unprognostic (3.29e-1)" "potential prognostic unfavorable (9.41e-4)" "unprognostic (3.99e-2)" "unprognostic (4.49e-2)" "potential prognostic unfavorable (2.62e-5)" "unprognostic (1.66e-1)" "unprognostic (1.34e-2)" "unprognostic (6.23e-2)" "unprognostic (5.76e-2)" "unprognostic (1.48e-1)" "unprognostic (4.44e-2)" "unprognostic (3.35e-2)" "unprognostic (2.15e-1)" "unprognostic (9.19e-3)" "unprognostic (1.08e-1)" "unprognostic (1.08e-1)" "unprognostic (1.83e-1)" "unprognostic (3.28e-3)" "unprognostic (5.35e-2)" NUP205 "C7orf14, KIAA0225" ENSG00000155561 "Nucleoporin 205" Q92621 7 135557917-135648757 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Sertoli cells: 106.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 81000 "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 39: Non-specific - Transcription" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 42 "unprognostic (2.69e-1)" "unprognostic (4.82e-2)" "unprognostic (1.19e-1)" "unprognostic (1.87e-2)" "unprognostic (1.20e-1)" "unprognostic (9.48e-2)" "unprognostic (3.12e-1)" "unprognostic (5.73e-3)" "unprognostic (1.49e-2)" "unprognostic (2.75e-3)" "potential prognostic favorable (1.25e-6)" "unprognostic (2.68e-1)" "unprognostic (7.03e-2)" "unprognostic (1.34e-2)" "unprognostic (3.55e-3)" "unprognostic (4.49e-2)" "unprognostic (5.49e-3)" "unprognostic (5.16e-2)" "unprognostic (8.87e-2)" "unprognostic (2.62e-2)" "unprognostic (1.10e-1)" "unprognostic (7.35e-3)" "unprognostic (1.03e-1)" "unprognostic (9.05e-2)" "unprognostic (1.50e-3)" "unprognostic (3.56e-2)" "unprognostic (9.41e-3)" "unprognostic (1.85e-1)" "unprognostic (9.97e-2)" "unprognostic (5.91e-2)" "unprognostic (1.27e-1)" NUP210 "FLJ22389, GP210, KIAA0906, POM210" ENSG00000132182 "Nucleoporin 210" Q8TEM1 3 13316235-13420322 "Metabolic proteins, Predicted membrane proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 36.8;lymphoid tissue: 30.8" "Cell type enhanced" "Detected in many" "B-cells: 112.3;Erythrocyte progenitors: 179.9;Megakaryocyte progenitors: 107.7;Monocyte progenitors: 149.5" "Cell type enhanced" "Detected in all" "leukocyte: 184.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Skin - Inner root sheath cells, Spleen - B-cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066888 Approved NA NA 57000 "Cluster 30: Non-specific - DNA binding" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 25: Non-specific - Transcription" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 102: Non-specific - Mixed function" 25 "HPA066888: " "unprognostic (3.35e-1)" "unprognostic (1.44e-1)" "unprognostic (3.25e-1)" "unprognostic (3.17e-1)" "unprognostic (5.67e-2)" "unprognostic (2.13e-1)" "unprognostic (3.26e-1)" "unprognostic (6.54e-2)" "unprognostic (7.65e-3)" "unprognostic (1.17e-2)" "unprognostic (2.58e-2)" "unprognostic (1.24e-2)" "unprognostic (8.88e-3)" "potential prognostic unfavorable (1.04e-5)" "unprognostic (2.78e-2)" "unprognostic (2.21e-1)" "unprognostic (1.51e-2)" "unprognostic (2.65e-1)" "unprognostic (2.07e-1)" "unprognostic (7.17e-2)" "unprognostic (9.47e-2)" "unprognostic (2.10e-1)" "unprognostic (9.06e-3)" "unprognostic (1.45e-1)" "unprognostic (2.14e-1)" "unprognostic (2.92e-3)" "unprognostic (4.68e-1)" "unprognostic (7.99e-2)" "unprognostic (7.10e-2)" "unprognostic (3.14e-2)" "unprognostic (1.55e-1)" NUP210L ENSG00000143552 "Nucleoporin 210 like" Q5VU65 1 153992690-154155116 "Cancer-related genes, Metabolic proteins, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 41 "testis: 24.8" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 56.0;Early primary spermatocytes: 107.5;Endometrial luminal cells: 82.8;Late primary spermatocytes: 54.8" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047195, HPA064245, HPA066707" Enhanced Approved "Nuclear bodies,Cytosol" No No "Cluster 57: Testis - Spermatogenesis" "Cluster 6: Non-specific - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 46: Skeletal myocytes - Muscle structure & formation" "Nuclear bodies" Cytosol "HPA047195: , HPA064245: , HPA066707: " NUP214 "CAIN, CAN, D9S46E, N214" ENSG00000126883 "Nucleoporin 214" P35658 9 131125573-131234663 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Host-virus interaction, mRNA transport, Protein transport, Translocation, Transport" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 119.1" "Cell type enhanced" "Detected in all" "Early spermatids: 329.0;Late spermatids: 593.5;Neutrophils: 448.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 419.3;neutrophil: 1254.6" "Group enriched" "Detected in all" 5 "granulocytes: 1254.6;monocytes: 419.3" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 67: Testis - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 50 "unprognostic (2.05e-1)" "unprognostic (1.81e-1)" "unprognostic (4.13e-2)" "unprognostic (6.48e-3)" "unprognostic (4.14e-3)" "unprognostic (4.52e-2)" "unprognostic (9.92e-2)" "unprognostic (1.96e-1)" "unprognostic (2.40e-1)" "unprognostic (4.59e-2)" "unprognostic (3.25e-3)" "unprognostic (4.35e-2)" "unprognostic (1.64e-2)" "unprognostic (1.51e-3)" "unprognostic (1.68e-1)" "unprognostic (1.18e-1)" "unprognostic (3.16e-2)" "unprognostic (2.04e-1)" "unprognostic (9.97e-2)" "unprognostic (1.82e-1)" "unprognostic (3.88e-2)" "unprognostic (7.54e-3)" "unprognostic (8.68e-3)" "unprognostic (7.67e-2)" "unprognostic (1.21e-1)" "unprognostic (6.15e-2)" "unprognostic (1.29e-1)" "unprognostic (1.06e-1)" "unprognostic (1.96e-2)" "unprognostic (2.68e-1)" "unprognostic (1.73e-1)" NUP35 MP44 ENSG00000163002 "Nucleoporin 35" Q8NFH5 2 183117513-183161680 "Essential proteins, Metabolic proteins, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 207.4;Late spermatids: 769.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018401, HPA018410, HPA018441" Enhanced Approved "Nucleoplasm,Nuclear membrane,Plasma membrane" No No "Cluster 43: Non-specific - Transcription & Translation" "Cluster 57: Testis - Spermatogenesis" "Cluster 31: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 45 "Nucleoplasm, Nuclear membrane" "Plasma membrane" "HPA018401: , HPA018410: , HPA018441: " "unprognostic (1.32e-2)" "unprognostic (2.57e-1)" "unprognostic (1.87e-1)" "unprognostic (2.13e-1)" "unprognostic (2.48e-1)" "unprognostic (5.58e-2)" "unprognostic (1.01e-1)" "unprognostic (9.93e-3)" "unprognostic (1.46e-1)" "potential prognostic unfavorable (5.70e-5)" "potential prognostic favorable (3.54e-4)" "unprognostic (2.81e-2)" "unprognostic (1.11e-2)" "unprognostic (4.70e-3)" "potential prognostic unfavorable (9.05e-4)" "unprognostic (4.99e-3)" "unprognostic (1.87e-2)" "unprognostic (4.77e-2)" "unprognostic (7.43e-2)" "unprognostic (2.01e-2)" "unprognostic (1.71e-1)" "unprognostic (1.40e-2)" "unprognostic (5.70e-2)" "potential prognostic unfavorable (2.30e-4)" "unprognostic (9.87e-2)" "unprognostic (1.08e-2)" "unprognostic (3.22e-2)" "unprognostic (1.22e-1)" "unprognostic (1.37e-1)" "unprognostic (2.51e-1)" "unprognostic (2.60e-1)" NUP37 "FLJ22618, MGC5585" ENSG00000075188 "Nucleoporin 37" Q8NFH4 12 102073103-102120120 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Chromosome partition, Mitosis, mRNA transport, Protein transport, Translocation, Transport" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 117.6;Migrating cytotrophoblasts: 108.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056300, HPA073708" Supported Supported Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 9: Non-specific - Receptor signaling" "Cluster 38: Non-specific - Transcription" "Cluster 27: Non-specific - Cell proliferation" 28 Nucleoplasm "HPA056300: , HPA073708: " "unprognostic (9.39e-3)" "unprognostic (3.17e-3)" "potential prognostic unfavorable (9.42e-4)" "unprognostic (1.28e-1)" "unprognostic (1.09e-1)" "potential prognostic favorable (8.04e-5)" "unprognostic (3.57e-3)" "unprognostic (4.75e-2)" "potential prognostic unfavorable (2.15e-4)" "unprognostic (3.10e-1)" "unprognostic (3.22e-3)" "unprognostic (9.65e-3)" "unprognostic (1.12e-1)" "validated prognostic unfavorable (4.01e-6)" "validated prognostic unfavorable (2.21e-4)" "potential prognostic unfavorable (4.36e-5)" "unprognostic (1.02e-3)" "unprognostic (1.04e-2)" "unprognostic (9.14e-3)" "unprognostic (3.94e-2)" "unprognostic (6.86e-3)" "unprognostic (1.84e-3)" "potential prognostic unfavorable (5.93e-4)" "unprognostic (5.78e-2)" "unprognostic (1.40e-2)" "unprognostic (7.51e-2)" "unprognostic (8.98e-3)" "unprognostic (6.51e-2)" "unprognostic (7.48e-2)" "unprognostic (9.49e-2)" "unprognostic (4.56e-2)" NUP42 "CG1, H_RG271G13.9, hCG1, NLP_1, NUPL2" ENSG00000136243 "Nucleoporin 42" O15504 7 23181841-23201011 "Metabolic proteins, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 332.6;Late primary spermatocytes: 201.5;Oligodendrocyte progenitor cells: 215.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058084 Supported "Nucleoplasm,Nuclear membrane,Cytosol" NA No "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 53: Neurons - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 21 "Nuclear membrane" "Nucleoplasm, Cytosol" "HPA058084: " "unprognostic (5.60e-2)" "unprognostic (4.97e-2)" "unprognostic (4.20e-1)" "unprognostic (7.60e-2)" "unprognostic (4.05e-2)" "unprognostic (1.50e-1)" "unprognostic (8.30e-2)" "unprognostic (3.72e-1)" "unprognostic (1.92e-3)" "unprognostic (4.03e-3)" "unprognostic (1.10e-1)" "unprognostic (1.95e-1)" "potential prognostic unfavorable (6.94e-5)" "unprognostic (4.25e-3)" "unprognostic (1.25e-1)" "unprognostic (7.27e-2)" "unprognostic (1.13e-1)" "unprognostic (4.07e-2)" "unprognostic (8.41e-2)" "unprognostic (2.99e-2)" "unprognostic (4.06e-3)" "unprognostic (2.01e-2)" "unprognostic (3.88e-2)" "unprognostic (9.63e-3)" "unprognostic (3.27e-2)" "unprognostic (1.23e-1)" "unprognostic (6.79e-3)" "unprognostic (1.01e-3)" "unprognostic (2.60e-2)" NUP43 "bA350J20.1, FLJ13287" ENSG00000120253 "Nucleoporin 43" Q8NFH3 6 149724315-149749665 "Essential proteins, Metabolic proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Chromosome partition, Mitosis, mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 119.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027126, HPA027291, HPA028500" Enhanced Approved "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 70 "Nucleoplasm, Nuclear speckles" Cytosol "HPA027126: , HPA027291: , HPA028500: " "unprognostic (9.78e-3)" "potential prognostic unfavorable (4.37e-5)" "unprognostic (9.90e-2)" "unprognostic (4.48e-3)" "unprognostic (1.20e-1)" "unprognostic (1.35e-1)" "unprognostic (1.94e-1)" "unprognostic (8.73e-2)" "unprognostic (2.59e-2)" "unprognostic (4.77e-3)" "unprognostic (2.22e-3)" "unprognostic (2.05e-1)" "unprognostic (1.04e-1)" "potential prognostic unfavorable (1.18e-7)" "unprognostic (7.51e-3)" "unprognostic (3.34e-2)" "unprognostic (2.32e-2)" "unprognostic (1.15e-1)" "unprognostic (7.12e-2)" "unprognostic (2.70e-2)" "unprognostic (1.04e-1)" "unprognostic (3.78e-1)" "unprognostic (6.72e-3)" "unprognostic (3.82e-2)" "unprognostic (3.67e-3)" "unprognostic (2.86e-2)" "unprognostic (2.09e-2)" "unprognostic (5.17e-2)" "unprognostic (1.98e-1)" "unprognostic (4.91e-2)" "unprognostic (1.14e-1)" NUP50 NPAP60L ENSG00000093000 "Nucleoporin 50" Q9UKX7 22 45163925-45188017 "Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 182.5;Esophageal apical cells: 165.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047162, HPA048328" Enhanced Enhanced "Nucleoplasm,Nuclear membrane" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 5: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 50 "Nucleoplasm, Nuclear membrane" "HPA047162: , HPA048328: " "unprognostic (2.20e-2)" "unprognostic (1.57e-1)" "unprognostic (5.08e-1)" "unprognostic (9.73e-2)" "unprognostic (3.39e-2)" "unprognostic (1.37e-1)" "unprognostic (2.88e-2)" "unprognostic (1.49e-3)" "unprognostic (6.56e-2)" "unprognostic (5.39e-3)" "unprognostic (4.78e-3)" "unprognostic (1.64e-2)" "unprognostic (2.75e-1)" "potential prognostic unfavorable (6.78e-4)" "unprognostic (1.14e-1)" "potential prognostic unfavorable (9.64e-7)" "unprognostic (6.81e-2)" "unprognostic (1.11e-1)" "unprognostic (2.34e-3)" "unprognostic (7.28e-2)" "unprognostic (6.02e-2)" "unprognostic (4.54e-2)" "potential prognostic unfavorable (4.15e-4)" "unprognostic (9.09e-2)" "unprognostic (1.61e-2)" "unprognostic (7.99e-2)" "unprognostic (2.74e-2)" "unprognostic (6.91e-3)" "unprognostic (3.23e-1)" "unprognostic (6.01e-2)" "unprognostic (5.13e-2)" NUP54 ENSG00000138750 "Nucleoporin 54" Q7Z3B4 4 76107562-76148485 "Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" Dystonia "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 268.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035929, HPA058122" Approved Approved Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 39: Testis - Nuclear processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 69 Nucleoplasm "HPA035929: , HPA058122: " "unprognostic (1.50e-1)" "unprognostic (1.57e-1)" "unprognostic (3.59e-2)" "unprognostic (3.40e-1)" "unprognostic (1.61e-2)" "unprognostic (1.76e-2)" "unprognostic (1.40e-1)" "unprognostic (8.27e-2)" "unprognostic (3.57e-1)" "unprognostic (9.39e-2)" "potential prognostic favorable (2.29e-6)" "unprognostic (3.07e-3)" "unprognostic (1.03e-1)" "potential prognostic unfavorable (2.22e-4)" "unprognostic (1.78e-1)" "potential prognostic unfavorable (4.05e-4)" "unprognostic (5.40e-3)" "unprognostic (6.06e-2)" "unprognostic (8.91e-3)" "unprognostic (2.00e-1)" "unprognostic (3.21e-1)" "unprognostic (1.57e-3)" "unprognostic (5.71e-2)" "unprognostic (5.19e-2)" "potential prognostic favorable (1.05e-4)" "unprognostic (7.05e-2)" "unprognostic (9.43e-2)" "unprognostic (2.83e-1)" "unprognostic (1.64e-1)" "unprognostic (4.07e-2)" "unprognostic (1.28e-1)" NUP58 "KIAA0410, NUP45, NUPL1" ENSG00000139496 "Nucleoporin 58" Q9BVL2 13 25301524-25365390 "Essential proteins, Metabolic proteins, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 400.4;Neutrophils: 626.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pancreas - Endothelial cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039360 Approved NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 19: Non-specific - Unknown function" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 91 "HPA039360: " "unprognostic (1.34e-1)" "unprognostic (4.04e-2)" "unprognostic (2.66e-3)" "unprognostic (1.80e-1)" "unprognostic (6.48e-2)" "unprognostic (3.37e-1)" "unprognostic (4.16e-2)" "unprognostic (1.11e-1)" "unprognostic (5.42e-3)" "potential prognostic favorable (7.29e-4)" "unprognostic (4.40e-2)" "unprognostic (8.60e-2)" "unprognostic (1.09e-3)" "unprognostic (2.79e-1)" "unprognostic (7.21e-3)" "unprognostic (3.72e-2)" "unprognostic (1.78e-1)" "unprognostic (2.32e-2)" "unprognostic (1.74e-2)" "unprognostic (7.06e-2)" "potential prognostic unfavorable (5.19e-4)" "unprognostic (1.65e-2)" "unprognostic (2.62e-2)" "unprognostic (1.39e-2)" "unprognostic (3.73e-2)" "unprognostic (4.90e-2)" "unprognostic (3.26e-1)" "unprognostic (7.40e-3)" "unprognostic (2.37e-1)" NUP62 "DKFZp547L134, FLJ20822, FLJ43869, IBSN, MGC841, p62, SNDI" ENSG00000213024 "Nucleoporin 62" P37198 19 49906825-49929764 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Host-virus interaction, mRNA transport, Protein transport, Translocation, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Early primary spermatocytes: 3.7;Early spermatids: 4.7;Epididymal clear cells: 2.0;Late primary spermatocytes: 9.3;Late spermatids: 6.9;Oocytes: 4.6;Thymic myoid cells: 1.4" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005435, CAB020724" Supported Supported "Nucleoplasm,Nuclear membrane" NA Yes "Cluster 13: Non-specific - Mitochondria" "Cluster 39: Testis - Nuclear processes" "Cluster 6: Non-specific - Immune response" "Cluster 4: Non-specific - Transcription" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 147 "Nuclear membrane" Nucleoplasm "CAB020724: , HPA005435: " "unprognostic (2.89e-2)" "unprognostic (7.03e-2)" "unprognostic (2.52e-1)" "unprognostic (5.35e-2)" "unprognostic (2.18e-1)" "unprognostic (7.62e-3)" "unprognostic (3.36e-1)" "unprognostic (5.09e-2)" "unprognostic (2.35e-2)" "unprognostic (8.46e-3)" "unprognostic (4.66e-2)" "unprognostic (3.38e-2)" "unprognostic (1.02e-2)" "potential prognostic unfavorable (5.10e-5)" "unprognostic (8.51e-3)" "unprognostic (2.17e-2)" "potential prognostic unfavorable (3.59e-4)" "unprognostic (1.05e-1)" "unprognostic (2.51e-1)" "unprognostic (2.56e-1)" "unprognostic (3.21e-1)" "unprognostic (2.82e-1)" "unprognostic (7.69e-2)" "unprognostic (1.74e-2)" "unprognostic (1.96e-1)" "unprognostic (8.38e-3)" "unprognostic (4.28e-3)" "unprognostic (1.52e-1)" "unprognostic (4.01e-1)" "unprognostic (1.33e-1)" "unprognostic (8.70e-2)" NUP62CL FLJ20130 ENSG00000198088 "Nucleoporin 62 C-terminal like" Q9H1M0 X 107123427-107206433 "Metabolic proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 16.3;fallopian tube: 16.2" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 65.2;Ependymal cells: 47.2;Epididymal efferent duct ciliated cells: 48.3;Erythrocyte progenitors: 95.6;Fallopian tube ciliated cells: 57.7;Sertoli cells: 98.8" "Group enriched" "Detected in some" 5 "choroid plexus epithelial cell: 21.6;ependymal cell: 56.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "memory B-cell: 2.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Lung - Respiratory ciliated cells, Stomach - Mitotic cells (Stomach), Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA001884 Approved NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 3: Choroid plexus - Cilium" "Cluster 36: Non-specific - mRNA processing" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 10 "HPA001884: " "unprognostic (4.15e-2)" "unprognostic (3.20e-3)" "unprognostic (7.35e-2)" "unprognostic (8.15e-3)" "unprognostic (1.13e-2)" "unprognostic (2.12e-2)" "unprognostic (2.94e-1)" "unprognostic (8.76e-2)" "unprognostic (7.99e-2)" "potential prognostic favorable (1.54e-6)" "unprognostic (8.69e-3)" "unprognostic (4.37e-2)" "unprognostic (1.84e-2)" "potential prognostic unfavorable (3.23e-5)" "unprognostic (2.16e-3)" "unprognostic (4.50e-2)" "unprognostic (8.96e-2)" "unprognostic (2.65e-1)" "unprognostic (2.37e-3)" "unprognostic (3.53e-2)" "unprognostic (7.11e-2)" "unprognostic (4.58e-3)" "unprognostic (1.65e-1)" "unprognostic (3.61e-2)" "unprognostic (2.29e-1)" "unprognostic (4.77e-1)" "unprognostic (5.75e-3)" "unprognostic (4.85e-2)" NUP85 "FLJ12549, NUP75" ENSG00000125450 "Nucleoporin 85" Q9BW27 17 75205659-75235758 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 119.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA061910, HPA062595" Supported Supported "Nucleoplasm,Vesicles,Actin filaments,Basal body,Cytosol" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 40 Nucleoplasm "Vesicles, Actin filaments, Basal body, Cytosol" "HPA061910: , HPA062595: " "unprognostic (5.68e-3)" "unprognostic (8.04e-2)" "unprognostic (3.23e-2)" "unprognostic (1.75e-1)" "unprognostic (2.88e-3)" "unprognostic (1.14e-1)" "unprognostic (1.71e-1)" "unprognostic (1.23e-2)" "unprognostic (2.67e-1)" "unprognostic (2.14e-2)" "potential prognostic unfavorable (5.72e-4)" "unprognostic (6.10e-2)" "unprognostic (5.74e-2)" "validated prognostic unfavorable (5.16e-7)" "validated prognostic unfavorable (7.96e-4)" "unprognostic (1.54e-3)" "potential prognostic unfavorable (4.73e-5)" "unprognostic (5.85e-2)" "unprognostic (5.19e-2)" "unprognostic (1.37e-1)" "unprognostic (3.68e-3)" "unprognostic (1.76e-1)" "potential prognostic unfavorable (7.70e-4)" "unprognostic (2.49e-2)" "unprognostic (2.44e-2)" "unprognostic (6.28e-3)" "unprognostic (9.00e-2)" "unprognostic (4.08e-3)" "unprognostic (4.93e-2)" "unprognostic (3.73e-2)" "unprognostic (3.63e-1)" NUP88 MGC8530 ENSG00000108559 "Nucleoporin 88" Q99567 17 5359668-5420164 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial glandular cells: 266.8;Late primary spermatocytes: 244.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen), Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002209, HPA021816" Approved Approved Nucleoplasm NA NA 4700 "Cluster 23: B-cells - Immunoglobulins" "Cluster 39: Testis - Nuclear processes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 42: Non-specific - Unknown function" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 33 Nucleoplasm "CAB002209: , HPA021816: " "unprognostic (1.97e-1)" "unprognostic (3.19e-3)" "unprognostic (9.50e-2)" "unprognostic (1.46e-1)" "unprognostic (5.81e-2)" "unprognostic (3.35e-2)" "unprognostic (5.08e-2)" "unprognostic (1.22e-3)" "unprognostic (1.13e-1)" "unprognostic (1.95e-2)" "potential prognostic favorable (1.97e-6)" "unprognostic (3.11e-3)" "unprognostic (8.31e-2)" "unprognostic (3.79e-2)" "unprognostic (3.64e-2)" "unprognostic (7.70e-3)" "unprognostic (1.62e-1)" "unprognostic (3.74e-1)" "unprognostic (2.48e-1)" "unprognostic (1.82e-1)" "unprognostic (3.51e-2)" "unprognostic (2.12e-2)" "unprognostic (1.73e-1)" "unprognostic (8.12e-2)" "unprognostic (4.70e-3)" "unprognostic (1.57e-1)" "unprognostic (2.38e-1)" "unprognostic (1.22e-1)" "unprognostic (1.67e-1)" "unprognostic (9.02e-2)" "unprognostic (5.89e-2)" NUP93 KIAA0095 ENSG00000102900 "Nucleoporin 93" Q8N1F7 16 56730118-56850286 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 230.3;Retinal bipolar cells: 173.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017937 Uncertain NA NA 63000 "Cluster 25: Non-specific - Unknown function" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 51: Neurons - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 50 "HPA017937: " "unprognostic (3.35e-2)" "unprognostic (6.08e-2)" "unprognostic (2.26e-1)" "unprognostic (1.80e-1)" "unprognostic (5.06e-2)" "unprognostic (2.19e-1)" "unprognostic (1.17e-1)" "potential prognostic favorable (1.43e-5)" "unprognostic (6.33e-2)" "unprognostic (1.77e-2)" "unprognostic (3.11e-2)" "unprognostic (1.53e-1)" "unprognostic (1.14e-1)" "potential prognostic unfavorable (8.53e-6)" "unprognostic (3.39e-3)" "unprognostic (7.09e-2)" "unprognostic (1.05e-2)" "unprognostic (7.03e-2)" "unprognostic (7.89e-3)" "unprognostic (2.93e-1)" "unprognostic (8.70e-2)" "unprognostic (3.72e-2)" "unprognostic (1.85e-3)" "unprognostic (5.44e-2)" "unprognostic (5.36e-2)" "unprognostic (9.91e-2)" "unprognostic (9.64e-2)" "unprognostic (2.10e-1)" "unprognostic (1.89e-1)" "unprognostic (1.46e-1)" "unprognostic (1.24e-1)" NUP98 "NUP196, NUP96, Nup98-96, Nup98-Nup96" ENSG00000110713 "Nucleoporin 98 and 96 precursor" P52948 11 3671083-3797792 "Cancer-related genes, Disease related genes, Essential proteins, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction, mRNA transport, Protein transport, Translocation, Transport" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 5 "Neutrophils: 1824.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 6500 "Cluster 4: Neutrophils - Degranulation" "Cluster 39: Testis - Nuclear processes" "Cluster 6: Non-specific - Immune response" "Cluster 24: Non-specific - Unknown function" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 56 "unprognostic (2.88e-1)" "unprognostic (3.26e-2)" "unprognostic (2.83e-2)" "unprognostic (1.44e-2)" "unprognostic (2.51e-1)" "unprognostic (1.44e-1)" "unprognostic (1.65e-1)" "unprognostic (5.02e-3)" "unprognostic (8.54e-2)" "unprognostic (4.68e-3)" "potential prognostic favorable (1.27e-5)" "unprognostic (6.28e-3)" "unprognostic (6.80e-2)" "unprognostic (9.09e-3)" "unprognostic (1.92e-1)" "unprognostic (2.04e-1)" "potential prognostic unfavorable (8.92e-4)" "unprognostic (1.33e-1)" "unprognostic (1.23e-1)" "unprognostic (4.70e-2)" "unprognostic (1.56e-2)" "unprognostic (4.00e-3)" "unprognostic (4.91e-3)" "unprognostic (1.15e-2)" "unprognostic (3.57e-2)" "unprognostic (1.00e-1)" "unprognostic (9.28e-2)" "unprognostic (2.25e-1)" "unprognostic (2.44e-1)" "unprognostic (7.47e-2)" "unprognostic (2.81e-2)" NUPR1 "COM1, p8" ENSG00000176046 "Nuclear protein 1, transcriptional regulator" O60356 16 28532708-28539008 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 1078.9" "Cell type enhanced" "Detected in many" "Bergmann glia: 46.5;Breast lactating cells: 50.8;Endometrial glandular cells: 64.6;Gastric chief cells: 65.5;Lacrimal acinar cells: 48.9;Podocytes: 49.6;Suprabasal keratinocytes: 45.2" "Group enriched" "Detected in many" 4 "astrocyte: 55.6;Bergmann glia: 62.4;fibroblast: 58.5;pericyte: 59.7;vascular associated smooth muscle cell: 74.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "basophil: 15.2" "Lineage enriched" "Detected in single" 18 "granulocytes: 15.2" "Cancer enhanced" "Detected in many" "prostate cancer: 199.5" "Minor Salivary Gland - Minor salivary glandular cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006349 Supported "Nucleoplasm,Cytokinetic bridge" Yes NA "Cluster 21: Neutrophils - Unknown function" "Cluster 8: Pancreas - Proteolysis" "Cluster 44: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 51: Secretory epithelial cells - Mixed function" 11 Nucleoplasm "Cytokinetic bridge" "HPA006349: " "unprognostic (6.35e-3)" "unprognostic (3.31e-3)" "unprognostic (4.02e-1)" "unprognostic (4.88e-2)" "unprognostic (3.56e-2)" "unprognostic (1.21e-1)" "unprognostic (5.58e-3)" "unprognostic (1.99e-3)" "unprognostic (6.26e-2)" "unprognostic (5.09e-2)" "unprognostic (1.01e-3)" "unprognostic (3.02e-2)" "unprognostic (3.55e-1)" "unprognostic (4.92e-3)" "unprognostic (6.39e-2)" "unprognostic (4.67e-3)" "unprognostic (5.59e-2)" "unprognostic (2.26e-1)" "unprognostic (1.44e-2)" "unprognostic (2.96e-2)" "unprognostic (3.13e-2)" "unprognostic (3.14e-3)" "unprognostic (2.51e-1)" "unprognostic (6.44e-2)" "unprognostic (8.63e-3)" "unprognostic (1.37e-1)" "unprognostic (1.21e-1)" "unprognostic (1.11e-1)" "unprognostic (8.82e-2)" "unprognostic (1.39e-3)" "unprognostic (6.17e-2)" NUPR2 "NUPR1L, P8" ENSG00000185290 "Nuclear protein 2, transcriptional regulator" A6NF83 7 56114681-56116417 "Predicted intracellular proteins" "Cell cycle, Growth arrest, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 18 "testis: 332.0" "Cell type enriched" "Detected in many" 6 "Late spermatids: 27700.1" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 30.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 5.2" "Group enriched" "Detected in many" 4 "granulocytes: 2.0;T-cells: 5.2" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 79: Testis - Spermatogenesis" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" "unprognostic (1.79e-1)" "unprognostic (4.64e-2)" "potential prognostic favorable (2.89e-5)" "unprognostic (6.26e-2)" "validated prognostic unfavorable (6.39e-5)" "validated prognostic unfavorable (4.54e-4)" "unprognostic (3.43e-1)" "unprognostic (9.70e-2)" "unprognostic (1.48e-3)" "unprognostic (3.67e-2)" "unprognostic (2.54e-1)" "unprognostic (7.35e-2)" "unprognostic (4.18e-3)" "unprognostic (7.67e-2)" "unprognostic (9.84e-2)" "unprognostic (7.65e-2)" "unprognostic (3.24e-2)" "unprognostic (5.28e-2)" "potential prognostic favorable (6.24e-4)" "unprognostic (7.97e-3)" "potential prognostic favorable (2.14e-4)" "unprognostic (2.56e-2)" "unprognostic (7.34e-2)" "unprognostic (6.70e-2)" "unprognostic (4.13e-2)" "unprognostic (9.21e-2)" "unprognostic (4.18e-2)" NUS1 "C6orf68, MGC7199, NgBR, TANGO14" ENSG00000153989 "NUS1 dehydrodolichyl diphosphate synthase subunit" Q96E22 6 117675469-117710727 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Angiogenesis, Differentiation, Lipid metabolism" "Developmental protein, Receptor, Transferase" "Congenital disorder of glycosylation, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027504 Supported Approved "Vesicles,Plasma membrane" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 3 Vesicles "Plasma membrane" "HPA027504: " "unprognostic (1.53e-3)" "unprognostic (2.30e-2)" "unprognostic (3.55e-3)" "unprognostic (6.14e-2)" "unprognostic (1.86e-2)" "unprognostic (3.31e-3)" "unprognostic (1.81e-2)" "unprognostic (4.95e-2)" "unprognostic (2.89e-3)" "unprognostic (6.77e-2)" "unprognostic (4.33e-3)" "unprognostic (1.68e-1)" "unprognostic (5.15e-2)" "unprognostic (1.25e-3)" "unprognostic (1.88e-3)" "unprognostic (6.70e-2)" "unprognostic (1.31e-1)" "unprognostic (5.04e-2)" "unprognostic (1.85e-1)" "unprognostic (1.37e-1)" "unprognostic (1.14e-1)" "unprognostic (7.76e-2)" "unprognostic (5.47e-2)" "unprognostic (1.84e-1)" "unprognostic (4.42e-2)" "unprognostic (4.97e-2)" "unprognostic (1.35e-1)" "unprognostic (1.56e-1)" "unprognostic (6.57e-2)" "unprognostic (1.30e-1)" "unprognostic (2.37e-1)" NUSAP1 "ANKT, BM037, FLJ13421, LNP, PRO0310p1, Q0310, SAPL" ENSG00000137804 "Nucleolar and spindle associated protein 1" Q9BXS6 15 41320794-41381050 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 83.5;lymphoid tissue: 94.6" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 5.0;Enteric transient amplifying cells: 17.9;Erythrocyte progenitors: 12.0;Extravillous trophoblasts: 9.2;Foveolar cells: 5.2;Gastric progenitor cells: 7.7;Hofbauer cells: 4.6;Migrating cytotrophoblasts: 5.2;Monocyte progenitors: 12.1;Oocytes: 4.6;Paneth cells: 11.6;Proximal tubule cells: 6.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 14 "basophil: 10.5;T-reg: 7.7" "Group enriched" "Detected in many" 14 "granulocytes: 10.5;T-cells: 7.7" "Low cancer specificity" "Detected in all" "Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA042904, HPA074847" Supported Approved "Nucleoplasm,Nucleoli,Nucleoli fibrillar center" Yes Yes "Cluster 9: T-regs - Cell cycle regulation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 58: Non-specific - Nuclear processes" "Cluster 27: Non-specific - Cell proliferation" 14 "Nucleoplasm, Nucleoli, Nucleoli fibrillar center" "HPA042904: , HPA074847: " "unprognostic (2.26e-1)" "unprognostic (6.47e-2)" "unprognostic (7.71e-2)" "unprognostic (4.36e-2)" "unprognostic (1.89e-1)" "unprognostic (5.96e-2)" "unprognostic (8.26e-2)" "unprognostic (6.89e-3)" "unprognostic (1.50e-2)" "potential prognostic unfavorable (2.21e-4)" "validated prognostic unfavorable (7.02e-8)" "validated prognostic unfavorable (1.24e-4)" "potential prognostic unfavorable (4.07e-12)" "validated prognostic unfavorable (4.10e-4)" "validated prognostic unfavorable (1.96e-7)" "validated prognostic unfavorable (3.24e-5)" "validated prognostic unfavorable (1.13e-4)" "unprognostic (3.75e-2)" "unprognostic (2.46e-2)" "unprognostic (5.47e-2)" "unprognostic (5.95e-2)" "potential prognostic unfavorable (4.12e-4)" "unprognostic (8.19e-3)" "unprognostic (1.87e-2)" "unprognostic (3.16e-1)" "unprognostic (1.70e-1)" "unprognostic (9.36e-3)" "unprognostic (1.15e-2)" "unprognostic (5.59e-2)" "unprognostic (1.84e-1)" "unprognostic (2.21e-1)" NUTF2 "NTF2, PP15" ENSG00000102898 "Nuclear transport factor 2" P61970 16 67846882-67872567 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 224.1;Extravillous trophoblasts: 411.3;Gastric progenitor cells: 211.5;Migrating cytotrophoblasts: 381.7;Platelets: 374.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040915, HPA040956" Supported NA NA 2700000 "Cluster 13: Non-specific - Mitochondria" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 53 "HPA040915: , HPA040956: " "unprognostic (2.78e-3)" "unprognostic (2.66e-2)" "unprognostic (9.06e-2)" "unprognostic (3.57e-1)" "unprognostic (1.17e-1)" "unprognostic (3.09e-2)" "unprognostic (1.39e-1)" "unprognostic (1.64e-1)" "potential prognostic unfavorable (8.54e-5)" "unprognostic (8.46e-3)" "validated prognostic unfavorable (1.40e-6)" "validated prognostic unfavorable (3.40e-4)" "unprognostic (4.82e-2)" "validated prognostic unfavorable (1.21e-4)" "validated prognostic unfavorable (4.97e-4)" "unprognostic (1.58e-3)" "unprognostic (1.48e-3)" "unprognostic (1.69e-1)" "unprognostic (6.83e-2)" "unprognostic (1.44e-1)" "unprognostic (2.94e-1)" "unprognostic (2.78e-3)" "unprognostic (1.67e-2)" "unprognostic (1.04e-1)" "unprognostic (4.78e-2)" "unprognostic (1.76e-1)" "unprognostic (1.06e-1)" "unprognostic (1.10e-1)" "unprognostic (1.26e-1)" "unprognostic (3.20e-1)" "unprognostic (5.65e-2)" NUTM1 "C15orf55, DKFZp434O192, FAM22H, NUT" ENSG00000184507 "NUT midline carcinoma family member 1" Q86Y26 15 34343315-34357737 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 82 "testis: 18.9" "Group enriched" "Detected in some" 6 "Early spermatids: 43.4;Late primary spermatocytes: 101.2" "Low cell type specificity" "Detected in some" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Gallbladder cancer: 1.9;head and neck cancer: 1.3" "Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA040421 Enhanced NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 15: Non-specific - Transcription" "Cluster 65: Non-specific - Unknown function" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" 19 "HPA040421: " NUTM2A FAM22A ENSG00000184923 "NUT family member 2A" Q8IVF1 10 87225448-87236908 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 2.0;Cardiomyocytes: 4.2;Cone photoreceptor cells: 2.1;Epicardial cells: 6.8;Gastric chief cells: 1.1;Mucous neck cells: 1.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" HPA064635 Approved "Nuclear bodies" NA NA "Cluster 68: Non-specific - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "Nuclear bodies" "HPA064635: " "unprognostic (1.58e-2)" "unprognostic (8.49e-2)" "unprognostic (1.76e-1)" "unprognostic (8.22e-2)" "unprognostic (8.63e-2)" "unprognostic (5.82e-2)" "unprognostic (1.20e-2)" "unprognostic (2.79e-2)" "unprognostic (6.40e-2)" "unprognostic (2.02e-1)" "unprognostic (1.85e-2)" NUTM2B "bA119F19.1, FAM22B" ENSG00000188199 "NUT family member 2B" A6NNL0 10 79703227-79714681 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "testis: 2.4" "Cell type enhanced" "Detected in some" "Adipocytes: 1.0;Cardiomyocytes: 5.0;Epicardial cells: 2.3;Thymocytes: 1.7" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA064635 Approved "Nuclear bodies" NA NA "Cluster 67: Testis - Mixed function" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 56: Non-specific - Sensory perception" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "Nuclear bodies" "HPA064635: " "unprognostic (2.09e-1)" "unprognostic (8.60e-3)" "unprognostic (2.26e-1)" "unprognostic (1.60e-1)" "unprognostic (2.24e-1)" "unprognostic (1.23e-1)" "unprognostic (2.18e-3)" "unprognostic (8.16e-2)" "unprognostic (1.21e-1)" "unprognostic (2.24e-1)" "unprognostic (3.03e-2)" "unprognostic (1.76e-1)" NUTM2D FAM22D ENSG00000214562 "NUT family member 2D" Q5VT03 10 87357720-87370695 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Cardiomyocytes: 4.5;Epicardial cells: 9.1;Retinal ganglion cells: 3.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" HPA064635 Approved "Nuclear bodies" NA NA "Cluster 68: Non-specific - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "Nuclear bodies" "HPA064635: " "unprognostic (4.25e-2)" "unprognostic (6.46e-2)" "unprognostic (2.90e-2)" "unprognostic (8.07e-2)" "unprognostic (2.60e-2)" "unprognostic (6.65e-2)" "potential prognostic favorable (3.40e-4)" "unprognostic (1.73e-1)" "unprognostic (3.70e-2)" "unprognostic (9.34e-2)" "unprognostic (1.99e-2)" "unprognostic (3.42e-2)" "unprognostic (2.42e-2)" "unprognostic (2.58e-1)" "unprognostic (4.30e-2)" "unprognostic (1.73e-1)" "unprognostic (4.57e-2)" "unprognostic (2.74e-1)" "unprognostic (2.76e-3)" "unprognostic (9.30e-2)" "unprognostic (1.82e-1)" "unprognostic (1.02e-1)" "unprognostic (1.29e-1)" "unprognostic (4.79e-2)" "unprognostic (1.77e-2)" "unprognostic (1.99e-2)" "unprognostic (3.53e-1)" "unprognostic (5.79e-2)" "unprognostic (1.58e-1)" NUTM2E FAM22E ENSG00000228570 "NUT family member 2E" B1AL46 10 79826739-79850878 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 21.3;Retinal horizontal cells: 20.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA064635 Approved "Nuclear bodies" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 65: Non-specific - Cell growth & division" "Nuclear bodies" "HPA064635: " NUTM2F "DKFZp434I1117, FAM22F" ENSG00000130950 "NUT family member 2F" A1L443 9 94318198-94328644 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 12 "testis: 1.8" "Cell type enhanced" "Detected in some" "Epididymal clear cells: 2.0;Kupffer cells: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" HPA064635 Approved "Nuclear bodies" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 22: Non-specific - Basic cellular functions" "Nuclear bodies" "HPA064635: " NUTM2G FAM22G ENSG00000188152 "NUT family member 2G" Q5VZR2 9 96928310-96940253 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "testis: 2.6" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 21.1;Epicardial cells: 36.4;Retinal ganglion cells: 7.7" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" HPA064635 Approved "Nuclear bodies" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 47: Testis - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 56: Non-specific - Sensory perception" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" "Nuclear bodies" "HPA064635: " "unprognostic (5.64e-2)" "unprognostic (4.54e-1)" "unprognostic (2.28e-1)" NVL NVL2 ENSG00000143748 "Nuclear VCP like" O15381 1 224227334-224330189 "Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028207, HPA028219, HPA028224, HPA028654" Supported Enhanced Nucleoli NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 49: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 45: Non-specific - Nuclear processes" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 13 Nucleoli "HPA028207: , HPA028219: , HPA028224: , HPA028654: " "unprognostic (1.09e-1)" "unprognostic (1.66e-1)" "unprognostic (4.24e-1)" "unprognostic (2.24e-2)" "unprognostic (1.24e-1)" "unprognostic (2.22e-2)" "unprognostic (2.89e-1)" "potential prognostic favorable (9.90e-4)" "unprognostic (1.76e-1)" "unprognostic (6.89e-2)" "unprognostic (6.79e-3)" "unprognostic (2.10e-1)" "unprognostic (4.63e-3)" "unprognostic (2.49e-3)" "unprognostic (1.86e-1)" "unprognostic (2.04e-1)" "unprognostic (1.26e-1)" "unprognostic (1.41e-3)" "unprognostic (2.45e-1)" "unprognostic (1.98e-1)" "unprognostic (1.28e-1)" "unprognostic (1.25e-1)" "unprognostic (1.79e-2)" "unprognostic (5.11e-2)" "unprognostic (2.75e-2)" "unprognostic (1.37e-1)" "unprognostic (4.84e-2)" "unprognostic (2.55e-1)" "unprognostic (5.07e-1)" "unprognostic (2.75e-1)" "unprognostic (3.67e-1)" NWD1 ENSG00000188039 "NACHT and WD repeat domain containing 1" Q149M9 19 16719847-16817963 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "choroid plexus: 76.5" "Cell type enriched" "Detected in many" 7 "Choroid plexus epithelial cells: 2510.4" "Cell type enriched" "Detected in many" 8 "choroid plexus epithelial cell: 1691.2" "Group enriched" "Detected in some" 5 "Prostate Adenocarcinoma (TCGA): 11.4;Uterine Corpus Endometrial Carcinoma (TCGA): 2.8" "Region enriched" "Detected in all" 16 "choroid plexus: 389.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "prostate cancer: 1.3" "Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary gland ductal cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075476 Approved Nucleoli,Cytosol NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 101: Choroid plexus epithelial cells - Ion transport" "Nucleoli, Cytosol" "HPA075476: " "unprognostic (3.10e-1)" "unprognostic (3.25e-3)" "unprognostic (2.94e-1)" "unprognostic (9.99e-3)" "unprognostic (1.31e-1)" "unprognostic (1.72e-1)" "unprognostic (2.90e-1)" NWD2 KIAA1239 ENSG00000174145 "NACHT and WD repeat domain containing 2" Q9ULI1 4 37244743-37449463 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 2.3;brain: 3.8;breast: 1.1" "Cell type enhanced" "Detected in many" "Adipocytes: 179.8;Brain excitatory neurons: 92.4;Brain inhibitory neurons: 32.9;Lactotrophs: 85.9;Other brain neurons: 131.9;Retinal amacrine cells: 41.4;Thyrotrophs: 59.3" "Cell type enhanced" "Detected in many" "deep-layer intratelencephalic: 304.2;upper-layer intratelencephalic: 261.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Minor Salivary Gland - Adipocytes (Minor salivary gland)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046911 Uncertain NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 109: Neurons - Neuronal signaling" 1 "HPA046911: " "unprognostic (2.92e-1)" NXF1 "DKFZp667O0311, Mex67, TAP" ENSG00000162231 "Nuclear RNA export factor 1" Q9UBU9 11 62792123-62806302 "Essential proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, mRNA transport, Protein transport, Translocation, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 152.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016327, HPA061593, HPA064429" Supported Enhanced Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 15: Bone marrow - Innate immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 20: Non-specific - Transcription regulation" 180 Nucleoplasm "CAB016327: , HPA061593: , HPA064429: " "unprognostic (8.04e-2)" "unprognostic (1.34e-1)" "unprognostic (5.59e-2)" "unprognostic (6.76e-2)" "unprognostic (6.78e-2)" "unprognostic (2.01e-2)" "unprognostic (1.06e-1)" "unprognostic (3.90e-1)" "unprognostic (8.11e-2)" "unprognostic (5.69e-2)" "unprognostic (4.67e-2)" "unprognostic (4.21e-2)" "unprognostic (1.62e-1)" "unprognostic (1.05e-3)" "unprognostic (1.93e-1)" "unprognostic (3.01e-1)" "unprognostic (2.15e-2)" "unprognostic (1.67e-2)" "unprognostic (7.16e-2)" "unprognostic (4.95e-2)" "unprognostic (2.23e-3)" "unprognostic (3.52e-3)" "unprognostic (2.60e-3)" "unprognostic (1.92e-2)" "unprognostic (2.83e-2)" "unprognostic (1.46e-1)" "unprognostic (4.84e-2)" "unprognostic (5.81e-2)" "unprognostic (3.60e-1)" "unprognostic (2.08e-2)" "potential prognostic favorable (4.52e-4)" NXF2 "CT39, TAPL-2" ENSG00000269405 "Nuclear RNA export factor 2" Q9GZY0 X 102247167-102326722 "Predicted intracellular proteins" "mRNA transport, Transport" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 14.3;testis: 10.2" "Cell type enhanced" "Detected in single" "Thyrotrophs: 1.4" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 8.2;prostate cancer: 9.9" HPA002079 Uncertain NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 102: Non-specific - Mixed function" 4 "HPA002079: " "unprognostic (5.75e-2)" "unprognostic (6.47e-3)" "unprognostic (1.37e-1)" "unprognostic (8.79e-2)" "unprognostic (4.84e-2)" "unprognostic (1.36e-2)" NXF2B bA353J17.1 ENSG00000269437 "Nuclear RNA export factor 2B" Q9GZY0 X 102360395-102440008 "Predicted intracellular proteins" "mRNA transport, Transport" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "epididymis: 14.3;testis: 6.9" "Cell type enriched" "Detected in single" 5 "Ependymal cells: 3.8" "Cell type enhanced" "Detected in some" "ependymal cell: 3.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 3.0;prostate cancer: 3.0" "Lung - Respiratory ciliated cells" HPA002079 Uncertain NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 20: Myeloma - Immune response" "Cluster 34: Ciliated cells - Cilia assembly & function" 1 "HPA002079: " "unprognostic (3.82e-2)" "unprognostic (1.08e-1)" "unprognostic (4.22e-1)" "unprognostic (4.02e-2)" "unprognostic (2.89e-2)" NXF3 ENSG00000147206 "Nuclear RNA export factor 3" Q9H4D5 X 103075810-103093143 "Predicted intracellular proteins" "mRNA transport, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 24.1;testis: 57.4" "Cell type enriched" "Detected in some" 4 "Sertoli cells: 249.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Pancreatic Adenocarcinoma (TCGA): 3.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 19.5;Sarcoma: 9.4" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Kidney - Podocytes, Skeletal muscle - Macrophages, Testis - Sertoli cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA003132, HPA046757" Approved Supported Nucleoplasm NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 7 Nucleoplasm "HPA003132: , HPA046757: " "unprognostic (4.79e-2)" "unprognostic (7.68e-2)" "unprognostic (2.43e-1)" "unprognostic (1.85e-1)" "unprognostic (5.06e-2)" "unprognostic (3.55e-2)" "unprognostic (1.04e-1)" "unprognostic (1.54e-2)" "unprognostic (6.66e-2)" NXN "FLJ12614, NRX" ENSG00000167693 Nucleoredoxin Q6DKJ4 17 799310-979776 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Differentiation, Wnt signaling pathway" "Developmental protein, Oxidoreductase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 95.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 345.8;Endometrial secretory cells: 507.9;Endometrial stromal cells: 324.1;Lymphatic endothelial cells: 350.6;Myonuclei: 446.6;Ocular epithelial cells: 340.7" "Cell type enhanced" "Detected in all" "endothelial cell: 640.1;vascular associated smooth muscle cell: 352.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023566 Approved Approved Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 4 Cytosol "HPA023566: " "unprognostic (9.80e-2)" "unprognostic (1.58e-2)" "unprognostic (1.13e-1)" "unprognostic (3.13e-1)" "unprognostic (6.20e-2)" "unprognostic (2.67e-2)" "unprognostic (1.09e-1)" "unprognostic (1.36e-3)" "unprognostic (8.18e-2)" "unprognostic (2.35e-1)" "unprognostic (2.19e-3)" "unprognostic (4.62e-2)" "unprognostic (1.08e-1)" "unprognostic (1.11e-1)" "unprognostic (9.69e-3)" "unprognostic (4.77e-2)" "unprognostic (1.17e-2)" "unprognostic (8.99e-2)" "unprognostic (2.29e-1)" "unprognostic (1.70e-2)" "unprognostic (1.63e-1)" "unprognostic (1.30e-1)" "unprognostic (2.75e-2)" "unprognostic (2.75e-1)" "unprognostic (2.56e-2)" "unprognostic (2.01e-2)" "potential prognostic unfavorable (5.29e-4)" "unprognostic (3.77e-2)" "unprognostic (1.31e-1)" "unprognostic (3.94e-2)" "unprognostic (2.33e-2)" NXNL1 "RDCVF, TXNL6" ENSG00000171773 "Nucleoredoxin like 1" Q96CM4 19 17455425-17460926 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 22 "choroid plexus: 26.4;retina: 59.7" "Cell type enriched" "Detected in some" 7 "Choroid plexus epithelial cells: 21.0" "Cell type enriched" "Detected in some" 7 "choroid plexus epithelial cell: 34.2" "Not detected" "Not detected" "Region enriched" "Detected in all" 5 "choroid plexus: 35.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 1: Neuronal - Visual perception" "Cluster 101: Choroid plexus epithelial cells - Ion transport" NXNL2 "C9orf121, RdCVF2" ENSG00000130045 "Nucleoredoxin like 2" Q5VZ03 9 88534033-88584274 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "cervix: 9.6;fallopian tube: 14.1" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 22.8;Early spermatids: 23.5;Endometrial ciliated cells: 63.4;Endometrial glandular cells: 23.6;Endometrial luminal cells: 23.9;Endometrial secretory cells: 43.4;Ependymal cells: 22.7;Epididymal efferent duct absorptive cells: 78.1;Epididymal efferent duct ciliated cells: 44.9;Fallopian secretory cells: 79.6;Fallopian tube ciliated cells: 58.8;Pituitary stem cells: 23.1;Proximal tubule cells: 32.1" "Cell type enhanced" "Detected in many" "ependymal cell: 22.6" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 7.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Breast - Breast glandular cells, Kidney - Proximal tubular cells, Stomach - Fibroblasts, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA045526 Uncertain Approved Cytosol NA NA "Cluster 41: Basophils - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 9: Non-specific - Receptor signaling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" Cytosol "HPA045526: " "unprognostic (2.88e-3)" "unprognostic (7.45e-3)" "unprognostic (1.07e-2)" "unprognostic (8.83e-2)" "potential prognostic favorable (3.41e-5)" "unprognostic (3.41e-1)" "unprognostic (9.39e-3)" "unprognostic (1.22e-1)" "unprognostic (8.96e-3)" "unprognostic (2.03e-1)" "unprognostic (7.93e-2)" "unprognostic (1.66e-2)" "unprognostic (1.31e-1)" "unprognostic (3.15e-1)" "unprognostic (3.69e-2)" NXPE1 "FAM55A, MGC34290" ENSG00000095110 "Neurexophilin and PC-esterase domain family member 1" Q8N323 11 114518934-114559881 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "intestine: 70.3" "Group enriched" "Detected in some" 4 "Colonocytes: 535.4;Enteric stem cells: 307.9;Enteric transient amplifying cells: 276.8;Goblet cells: 586.1" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in some" 23 "Colon Adenocarcinoma (TCGA): 11.6;Rectum Adenocarcinoma (TCGA): 10.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enterocytes, Testis - Early spermatids, Testis - Late spermatids" HPA049133 Enhanced "Intracellular and membrane" "No annotated function" NA NA "Cluster 17: Intestine - Digestion" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 5 "HPA049133: " "unprognostic (1.57e-2)" "potential prognostic favorable (8.67e-4)" "unprognostic (2.22e-2)" "unprognostic (1.95e-2)" NXPE2 "FAM55B, FLJ25224" ENSG00000204361 "Neurexophilin and PC-esterase domain family member 2" Q96DL1 11 114678527-114707069 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 17 "epididymis: 23.8;intestine: 9.2;salivary gland: 20.0" "Cell type enhanced" "Detected in some" "Colonocytes: 12.6;Enteric stem cells: 8.7;Enteric transient amplifying cells: 6.6;Epididymal principal cells: 44.3;Goblet cells: 35.8;Neuroendocrine cells: 11.6;Salivary acinar cells: 51.2;Salivary myoepithelial cells: 7.8;Submucosal glandular cells: 10.8" "Low cell type specificity" "Detected in some" "Group enriched" "Detected in some" 4 "Colon Adenocarcinoma (TCGA): 3.0;Rectum Adenocarcinoma (TCGA): 2.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Minor Salivary Gland - Minor salivary glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA039744, HPA039876" Enhanced NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 38: Secretory epithelial cells - Exocrine secretion" "HPA039744: , HPA039876: " "unprognostic (6.46e-3)" "unprognostic (1.27e-1)" "unprognostic (5.85e-2)" "unprognostic (6.32e-2)" "unprognostic (9.64e-3)" "unprognostic (5.69e-2)" NXPE3 "FAM55C, MGC15606" ENSG00000144815 "Neurexophilin and PC-esterase domain family member 3" Q969Y0 3 101779177-101843743 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 55.7;tongue: 47.6" "Cell type enhanced" "Detected in many" "Myonuclei: 148.7;Neutrophil progenitors: 88.9;Oligodendrocytes: 221.3;Plasma cells: 130.9" "Cell type enhanced" "Detected in all" "oligodendrocyte: 288.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036259 Uncertain Approved Nucleoplasm,Vesicles "Secreted to blood" "No annotated function" NA NA 6000 "Cluster 6: T-cells - T-cell receptor" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 44: Plasma cells - Antibody production & secretion" 5 Vesicles Nucleoplasm "HPA036259: " "unprognostic (3.12e-1)" "unprognostic (2.30e-1)" "unprognostic (2.76e-2)" "unprognostic (1.34e-1)" "unprognostic (1.05e-1)" "unprognostic (1.85e-1)" "unprognostic (1.15e-1)" "unprognostic (7.63e-3)" "potential prognostic unfavorable (2.50e-4)" "unprognostic (5.03e-3)" "unprognostic (3.07e-2)" "unprognostic (9.63e-3)" "unprognostic (8.26e-2)" "unprognostic (2.45e-2)" "unprognostic (7.01e-2)" "unprognostic (1.84e-1)" "unprognostic (1.13e-1)" "unprognostic (9.90e-2)" "unprognostic (2.45e-2)" "unprognostic (2.02e-2)" "unprognostic (2.83e-1)" "unprognostic (3.34e-1)" "unprognostic (2.99e-2)" "unprognostic (1.13e-1)" "unprognostic (8.04e-2)" "unprognostic (2.00e-1)" "unprognostic (3.46e-1)" "unprognostic (2.86e-1)" "unprognostic (3.62e-2)" NXPE4 "C11orf33, FAM55D, FLJ20127" ENSG00000137634 "Neurexophilin and PC-esterase domain family member 4" Q6UWF7 11 114570591-114595786 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "intestine: 112.3;salivary gland: 72.7" "Group enriched" "Detected in some" 5 "Colonocytes: 169.2;Enteric stem cells: 127.3;Enteric transient amplifying cells: 109.5;Goblet cells: 102.0;Salivary acinar cells: 67.8" "Cell type enhanced" "Detected in single" "mammillary body: 1.3" "Group enriched" "Detected in some" 15 "Colon Adenocarcinoma (TCGA): 18.6;Rectum Adenocarcinoma (TCGA): 19.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Plasma cells, Colon - Colon enterocytes, Stomach - Plasma cells" "Low region specificity" "Detected in all" HPA042801 Enhanced "Secreted to digestive system" "No annotated function" NA NA "Cluster 17: Intestine - Digestion" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" "HPA042801: " "unprognostic (6.88e-2)" "unprognostic (6.33e-2)" "unprognostic (2.20e-1)" "unprognostic (2.53e-2)" "unprognostic (6.71e-2)" NXPH1 ENSG00000122584 "Neurexophilin 1" P58417 7 8433609-8752961 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 16 "adrenal gland: 39.5;brain: 26.8" "Cell type enhanced" "Detected in some" "Adrenal cortex cells: 641.4;Adrenal medulla cells: 414.8;Brain excitatory neurons: 144.3;Brain inhibitory neurons: 681.1;Lactotrophs: 246.5;Oligodendrocyte progenitor cells: 1898.6;Other brain neurons: 206.7;Thyrotrophs: 371.7" "Cell type enhanced" "Detected in all" "cerebellar inhibitory: 1941.2;LAMP5-LHX6 and Chandelier: 2484.1;MGE interneuron: 3093.5;oligodendrocyte precursor cell: 2114.0" "Group enriched" "Detected in some" 47 "Breast Invasive Carcinoma (TCGA): 7.3;Glioblastoma Multiforme (TCGA): 21.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney cancer: 3.7;Neuroblastoma: 3.6" "Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Thyrotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted in brain" "No annotated function" NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 1: Neurons - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 109: Neurons - Neuronal signaling" 9 "unprognostic (5.76e-2)" "unprognostic (1.55e-1)" "unprognostic (1.30e-1)" "unprognostic (1.01e-2)" NXPH2 NPH2 ENSG00000144227 "Neurexophilin 2" O95156 2 138669157-138780390 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "brain: 4.1;kidney: 3.8;ovary: 4.1;retina: 2.1" "Cell type enhanced" "Detected in some" "Brain inhibitory neurons: 81.0;Mesothelial cells: 21.8;Podocytes: 27.6;Renal collecting duct intercalated cells: 315.6;Respiratory ionocytes: 76.2;Retinal bipolar cells: 36.0;Salivary ionocytes: 49.2" "Group enriched" "Detected in many" 7 "cerebellar inhibitory: 304.0;CGE interneuron: 192.4;deep-layer near-projecting: 354.8;LAMP5-LHX6 and Chandelier: 256.3;lower rhombic lip: 316.8;MGE interneuron: 187.7;midbrain-derived inhibitory: 252.5;splatter: 107.0" "Cancer enhanced" "Detected in single" "Kidney Chromophobe (TCGA): 1.8" "Group enriched" "Detected in many" 4 "medulla oblongata: 15.6;midbrain: 16.2;pons: 27.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 3.6;Rhabdoid: 6.5" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells, Kidney - Intercalated cells, Minor Salivary Gland - Minor salivary gland ductal cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA034759 Approved "Secreted in brain" "No annotated function" NA Yes "Cluster 36: Brain & Liver - Signaling" "Cluster 49: Hindbrain - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 109: Neurons - Neuronal signaling" 10 "HPA034759: " "unprognostic (4.88e-2)" "unprognostic (7.50e-2)" NXPH3 NPH3 ENSG00000182575 "Neurexophilin 3" O95157 17 49575871-49583827 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 34.6;brain: 22.4" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 6.6;Epididymal principal cells: 5.4;Müller glia: 6.4;Peritubular myoid cells: 17.4;Pituicytes/FSCs: 7.4;Retinal bipolar cells: 15.1;Smooth muscle cells: 29.8;Vascular smooth muscle cells: 16.7" "Cell type enhanced" "Detected in many" "deep-layer corticothalamic and 6b: 20.9;deep-layer near-projecting: 30.0" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 4.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 2.5" "Adipose subcutaneous - Smooth muscle cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 4 "cerebellum: 54.8" HPA073819 Approved "Vesicles,Mitotic spindle" "Secreted in brain" "No annotated function" Yes NA "Cluster 74: Non-specific - Signal transduction" "Cluster 37: Neurons - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 62: Smooth muscle cells - Muscle contraction" 32 Vesicles "Mitotic spindle" "HPA073819: " "unprognostic (4.21e-1)" "unprognostic (3.44e-2)" "unprognostic (1.98e-1)" "unprognostic (1.50e-1)" "unprognostic (3.49e-1)" "unprognostic (5.35e-3)" "unprognostic (1.70e-1)" "unprognostic (1.05e-1)" "unprognostic (6.20e-3)" "unprognostic (9.14e-2)" "unprognostic (3.70e-2)" NXPH4 NPH4 ENSG00000182379 "Neurexophilin 4" O95158 12 57216794-57226449 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.5;skin 1: 18.4" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 11.6;Brain excitatory neurons: 7.7;Cytotrophoblasts: 39.4;Esophageal basal cells: 10.8;Esophageal suprabasal cells: 6.7;Müller glia: 17.7;Oocytes: 13.8;Prostatic glandular cells: 12.7;Suprabasal keratinocytes: 8.9;Syncytiotrophoblasts: 34.9" "Cell type enhanced" "Detected in many" "deep-layer corticothalamic and 6b: 15.4;mammillary body: 21.0;upper rhombic lip: 15.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal medulla cells, Prostate - Prostate glandular cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Secreted in brain" "No annotated function" NA NA "Cluster 2: Non-specific - Mixed function" "Cluster 43: Hindbrain - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 9 "unprognostic (7.55e-3)" "unprognostic (8.22e-3)" "unprognostic (1.98e-2)" "unprognostic (2.18e-1)" "unprognostic (1.06e-1)" "unprognostic (1.02e-1)" "unprognostic (1.20e-3)" "unprognostic (2.18e-2)" "unprognostic (1.19e-1)" "unprognostic (7.45e-2)" "unprognostic (2.40e-1)" "unprognostic (2.53e-1)" "potential prognostic unfavorable (8.24e-6)" "potential prognostic unfavorable (1.41e-4)" "unprognostic (1.65e-2)" "unprognostic (7.78e-2)" "unprognostic (3.70e-2)" "unprognostic (1.73e-1)" "unprognostic (2.13e-2)" "unprognostic (3.27e-1)" "unprognostic (1.68e-1)" "potential prognostic favorable (9.16e-4)" "unprognostic (1.57e-1)" "unprognostic (5.90e-2)" "unprognostic (5.33e-3)" "unprognostic (6.27e-3)" "unprognostic (2.04e-3)" "unprognostic (2.99e-1)" "unprognostic (1.57e-1)" "unprognostic (1.53e-1)" "unprognostic (1.09e-1)" NXT1 "MTR2, P15" ENSG00000132661 "Nuclear transport factor 2 like export factor 1" Q9UKK6 20 23350791-23354771 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 151.0;Oocytes: 207.2;Suprabasal keratinocytes: 152.8" "Cell type enhanced" "Detected in all" "vascular associated smooth muscle cell: 19.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047471 Supported Nucleoplasm,Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 15: Bone marrow - Innate immune response" "Cluster 25: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 17: Non-specific - RNA processing" 17 Nucleoplasm Cytosol "HPA047471: " "unprognostic (1.21e-1)" "unprognostic (1.41e-1)" "unprognostic (6.25e-2)" "unprognostic (4.94e-1)" "unprognostic (1.37e-1)" "unprognostic (6.79e-2)" "unprognostic (1.76e-1)" "unprognostic (5.86e-2)" "unprognostic (4.34e-2)" "unprognostic (8.85e-2)" "unprognostic (5.59e-2)" "unprognostic (6.52e-2)" "unprognostic (7.55e-3)" "potential prognostic unfavorable (5.03e-4)" "unprognostic (4.12e-3)" "unprognostic (2.77e-2)" "unprognostic (1.06e-2)" "unprognostic (4.18e-2)" "unprognostic (2.09e-1)" "unprognostic (1.08e-1)" "unprognostic (1.58e-1)" "unprognostic (4.46e-2)" "unprognostic (2.38e-1)" "unprognostic (1.80e-1)" "unprognostic (1.96e-1)" "unprognostic (3.50e-2)" "unprognostic (3.95e-1)" "unprognostic (2.02e-1)" "unprognostic (1.60e-1)" "potential prognostic unfavorable (1.02e-4)" "unprognostic (7.91e-2)" NXT2 P15-2 ENSG00000101888 "Nuclear transport factor 2 like export factor 2" Q9NPJ8 X 109535781-109544698 "Predicted intracellular proteins" "mRNA transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 34.7;Parietal cells: 33.6;Syncytiotrophoblasts: 33.1" "Cell type enhanced" "Detected in many" "ependymal cell: 12.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024199, HPA072010" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 39: Astrocytes - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 17: Non-specific - RNA processing" 17 "Nucleoplasm, Cytosol" "HPA024199: , HPA072010: " "unprognostic (4.36e-2)" "unprognostic (1.29e-1)" "unprognostic (4.98e-2)" "unprognostic (2.08e-1)" "unprognostic (3.23e-1)" "unprognostic (4.92e-2)" "unprognostic (2.79e-2)" "unprognostic (5.20e-2)" "unprognostic (3.08e-1)" "potential prognostic unfavorable (5.26e-4)" "potential prognostic favorable (1.24e-5)" "unprognostic (3.19e-1)" "unprognostic (2.37e-1)" "unprognostic (1.72e-2)" "unprognostic (9.46e-3)" "unprognostic (1.57e-1)" "unprognostic (2.53e-2)" "unprognostic (7.29e-2)" "unprognostic (7.96e-2)" "unprognostic (5.60e-2)" "unprognostic (9.79e-2)" "unprognostic (8.35e-3)" "unprognostic (1.36e-1)" "unprognostic (6.20e-2)" "unprognostic (4.95e-2)" "unprognostic (6.82e-2)" "unprognostic (2.21e-1)" "unprognostic (4.48e-3)" "unprognostic (4.76e-1)" "unprognostic (1.17e-1)" "unprognostic (2.49e-1)" NYAP1 "C7orf51, FLJ37538, KIAA1486L" ENSG00000166924 "Neuronal tyrosine phosphorylated phosphoinositide-3-kinase adaptor 1" Q6ZVC0 7 100483927-100494802 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.4;pituitary gland: 20.9" "Cell type enhanced" "Detected in many" "Astrocytes: 13.8;Brain inhibitory neurons: 14.0;Breast myoepithelial cells: 18.9;Corticotrophs: 14.8;Ependymal cells: 14.1;Epicardial cells: 31.8;Epididymal basal cells: 20.6;Gonadotrophs: 14.3;Lactotrophs: 29.2;Other brain neurons: 18.2;Renal collecting duct principal cells: 17.8;Retinal horizontal cells: 14.0;Sertoli cells: 32.6;Somatotrophs: 19.7;Thyrotrophs: 29.7" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 7.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 6.6;Rhabdoid: 8.3" "Colon - Colon enteroendocrine cells, Kidney - Fibroblasts, Pituitary gland - Lactotropes, Prostate - Fibroblasts, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022251 Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 2 Vesicles "Golgi apparatus" "HPA022251: " "unprognostic (8.20e-2)" "unprognostic (2.52e-1)" "unprognostic (4.79e-3)" "unprognostic (2.63e-1)" "potential prognostic favorable (8.96e-4)" "unprognostic (1.62e-1)" NYAP2 KIAA1486 ENSG00000144460 "Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2" Q9P242 2 225399710-225729887 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 2.6;retina: 3.6" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 138.0;Brain inhibitory neurons: 314.6;Corticotrophs: 207.8;Gonadotrophs: 154.1;Lactotrophs: 155.4;Myonuclei: 88.2;Other brain neurons: 200.3;Retinal amacrine cells: 74.7;Retinal bipolar cells: 554.9;Somatotrophs: 108.4;Thyrotrophs: 197.6" "Cell type enhanced" "Detected in many" "midbrain-derived inhibitory: 1450.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045531 Uncertain Approved "Nucleoplasm,Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Basal body,Cytosol" Yes NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 6 "Microtubules, Primary cilium, Cytosol" "Nucleoplasm, Cytokinetic bridge, Mitotic spindle, Basal body" "HPA045531: " "unprognostic (6.23e-3)" NYNRIN "CGIN1, FLJ11811, KIAA1305" ENSG00000205978 "NYN domain and retroviral integrase containing" Q9P2P1 14 24399003-24419283 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Epididymal efferent duct absorptive cells: 28.7;Epididymal principal cells: 62.2;Pituicytes/FSCs: 51.7;Prostatic hillock cells: 29.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 14.8" "Adrenal gland - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018945 Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 64: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 4 "Golgi apparatus" "Nucleoplasm, Vesicles" "HPA018945: " "potential prognostic favorable (3.42e-4)" "unprognostic (1.94e-2)" "unprognostic (5.59e-2)" "unprognostic (1.37e-1)" "unprognostic (1.43e-2)" "unprognostic (2.36e-1)" "unprognostic (2.42e-1)" "unprognostic (8.20e-2)" "unprognostic (3.79e-2)" "unprognostic (4.17e-2)" "potential prognostic favorable (9.01e-5)" "unprognostic (1.48e-3)" "unprognostic (2.41e-1)" "unprognostic (4.20e-1)" "unprognostic (1.06e-1)" "unprognostic (9.22e-2)" "potential prognostic unfavorable (8.35e-4)" "unprognostic (1.20e-1)" "unprognostic (2.42e-2)" "unprognostic (2.44e-1)" "unprognostic (1.87e-1)" "unprognostic (3.14e-1)" "unprognostic (9.97e-2)" "unprognostic (2.13e-2)" "unprognostic (4.43e-2)" "unprognostic (1.39e-1)" "unprognostic (1.08e-3)" "unprognostic (4.22e-2)" "unprognostic (1.04e-1)" "unprognostic (2.00e-1)" "unprognostic (2.01e-1)" NYX "CLRP, CSNB1, CSNB1A, CSNB4" ENSG00000188937 Nyctalopin Q9GZU5 X 41447343-41475710 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Congenital stationary night blindness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 4 "Retinal bipolar cells: 31.9" "Cell type enriched" "Detected in some" 11 "choroid plexus epithelial cell: 12.4" "Not detected" "Not detected" "Region enriched" "Detected in single" 4 "choroid plexus: 1.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Uterine cancer: 1.2" "Kidney - Proximal tubular cells" "Not detected" "Not detected" "Not detected" "Not detected" "Intracellular and membrane" Other NA NA "Cluster 36: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 2 OAF MGC52117 ENSG00000184232 "Out at first homolog" Q86UD1 11 120211032-120230334 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "liver: 407.9" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 160.6;Astrocytes: 126.1;Colonocytes: 139.2;Enterocytes: 131.1;Fibro-adipogenic progenitors: 130.6;Fibroblasts: 133.0;Hepatocytes: 282.0;Lymphatic endothelial cells: 154.5;Müller glia: 377.0;Pancreatic acinar cells: 430.5;Urothelial cells: 138.8" "Cell type enhanced" "Detected in many" "astrocyte: 78.3;fibroblast: 152.3;pericyte: 125.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 3.3;intermediate monocyte: 1.6;myeloid DC: 2.4" "Group enriched" "Detected in many" 14 "dendritic cells: 2.4;monocytes: 3.3" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Lung - Fibroblasts_2, Minor Salivary Gland - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047412 Uncertain Approved Nucleoplasm "Secreted - unknown location" "No annotated function" NA NA 42000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 53: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 110: Mural cells - ECM organization" 21 Nucleoplasm "HPA047412: " "unprognostic (2.83e-3)" "unprognostic (7.99e-2)" "unprognostic (7.18e-3)" "unprognostic (5.75e-3)" "unprognostic (1.44e-1)" "unprognostic (5.22e-2)" "unprognostic (2.65e-2)" "potential prognostic unfavorable (3.00e-4)" "potential prognostic unfavorable (6.04e-4)" "unprognostic (3.74e-2)" "unprognostic (9.01e-3)" "potential prognostic unfavorable (5.99e-4)" "unprognostic (1.70e-2)" "unprognostic (1.85e-1)" "unprognostic (1.51e-3)" "unprognostic (4.71e-3)" "unprognostic (3.99e-3)" "unprognostic (1.22e-1)" "unprognostic (1.74e-1)" "unprognostic (5.37e-2)" "unprognostic (2.13e-1)" "unprognostic (5.15e-2)" "unprognostic (1.06e-1)" "unprognostic (8.36e-2)" "unprognostic (8.33e-2)" "unprognostic (4.71e-1)" "unprognostic (3.04e-2)" "unprognostic (4.62e-2)" "unprognostic (1.04e-1)" "unprognostic (1.10e-1)" "unprognostic (4.09e-2)" OARD1 "C6orf130, dJ34B21.3, MGC19570, TARG1" ENSG00000124596 "O-acyl-ADP-ribose deacylase 1" Q9Y530 6 41033627-41097787 "Disease related genes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 496.5;Late primary spermatocytes: 242.0;Late spermatids: 286.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029036 Approved Supported Nucleoplasm,Nucleoli NA NA "Cluster 24: Non-specific - Transcription" "Cluster 76: Non-specific - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 3 "Nucleoplasm, Nucleoli" "HPA029036: " "unprognostic (3.17e-2)" "unprognostic (2.07e-2)" "unprognostic (1.87e-2)" "unprognostic (7.82e-2)" "unprognostic (7.29e-2)" "unprognostic (4.17e-1)" "unprognostic (1.62e-1)" "unprognostic (1.66e-1)" "unprognostic (9.48e-2)" "validated prognostic favorable (3.05e-7)" "validated prognostic favorable (2.96e-6)" "unprognostic (4.66e-2)" "unprognostic (4.32e-2)" "unprognostic (7.76e-2)" "unprognostic (3.06e-1)" "unprognostic (9.10e-2)" "unprognostic (1.95e-1)" "unprognostic (5.65e-2)" "unprognostic (1.46e-1)" "unprognostic (9.37e-2)" "unprognostic (9.83e-2)" "unprognostic (2.20e-1)" "unprognostic (4.77e-3)" "unprognostic (1.30e-2)" "unprognostic (1.09e-2)" "unprognostic (3.84e-1)" "unprognostic (1.59e-1)" "unprognostic (1.93e-1)" "unprognostic (5.45e-3)" OAS1 "IFI-4, OIAS, OIASI" ENSG00000089127 "2'-5'-oligoadenylate synthetase 1" P00973 12 112905856-112933219 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" "Nucleotidyltransferase, RNA-binding, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 85.6;urinary bladder: 103.7" "Cell type enhanced" "Detected in many" "Colonocytes: 128.5;Esophageal apical cells: 839.6;Esophageal suprabasal cells: 155.3;Foveolar cells: 123.9;Hofbauer cells: 151.5;Urothelial cells: 380.9" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 85.8;endothelial cell: 43.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 575.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Skeletal muscle - Fibroblasts, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA003657, CAB021104" Uncertain Supported Nucleoplasm,Cytosol "Intracellular and membrane" Immunity NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 69: Urothelial cells - Basic cellular functions" 6 "Nucleoplasm, Cytosol" "CAB021104: , HPA003657: " "unprognostic (4.75e-3)" "unprognostic (2.62e-1)" "unprognostic (2.29e-1)" "unprognostic (1.09e-2)" "unprognostic (1.06e-1)" "unprognostic (2.14e-1)" "unprognostic (3.29e-2)" "unprognostic (2.15e-1)" "unprognostic (3.40e-2)" "unprognostic (2.75e-1)" "unprognostic (7.42e-3)" "unprognostic (1.90e-1)" "unprognostic (1.89e-2)" "unprognostic (1.24e-2)" "unprognostic (1.21e-1)" "potential prognostic unfavorable (9.00e-5)" "unprognostic (3.04e-1)" "unprognostic (7.77e-2)" "unprognostic (2.46e-1)" "unprognostic (1.10e-1)" "unprognostic (8.66e-2)" "potential prognostic unfavorable (3.22e-5)" "unprognostic (1.41e-2)" "unprognostic (2.34e-1)" "unprognostic (9.99e-2)" "unprognostic (2.64e-2)" "unprognostic (2.68e-1)" "unprognostic (5.74e-2)" "unprognostic (9.14e-3)" "unprognostic (2.06e-2)" "unprognostic (6.70e-2)" OAS2 ENSG00000111335 "2'-5'-oligoadenylate synthetase 2" P29728 12 112978395-113011723 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" "Nucleotidyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 63.3" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 31.8;Foveolar cells: 20.1;Kupffer cells: 33.8;Macrophages: 18.6;monocytes: 22.6;NK-cells: 17.9;Ocular epithelial cells: 19.1;Plasma cells: 22.3;T-cells: 18.7;Thymocytes: 19.5;Vascular endothelial cells: 22.7" "Cell type enhanced" "Detected in some" "endothelial cell: 55.6;leukocyte: 28.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA003320, CAB024984" Approved Approved Centrosome NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 3 Centrosome "CAB024984: , HPA003320: " "unprognostic (3.65e-2)" "unprognostic (2.37e-1)" "unprognostic (1.66e-1)" "unprognostic (1.01e-1)" "unprognostic (1.81e-2)" "unprognostic (8.26e-2)" "unprognostic (6.01e-2)" "unprognostic (9.66e-2)" "unprognostic (1.67e-1)" "unprognostic (2.52e-1)" "unprognostic (2.54e-2)" "unprognostic (2.67e-1)" "unprognostic (6.91e-3)" "unprognostic (1.42e-1)" "unprognostic (2.64e-2)" "unprognostic (4.54e-2)" "unprognostic (3.63e-2)" "unprognostic (9.08e-2)" "unprognostic (1.12e-1)" "unprognostic (4.43e-2)" "unprognostic (4.49e-2)" "potential prognostic unfavorable (1.07e-4)" "unprognostic (2.97e-2)" "unprognostic (5.48e-1)" "unprognostic (2.25e-1)" "unprognostic (3.40e-2)" "unprognostic (2.08e-1)" "unprognostic (6.88e-2)" "unprognostic (2.25e-2)" "unprognostic (9.46e-2)" "unprognostic (6.90e-2)" OAS3 ENSG00000111331 "2'-5'-oligoadenylate synthetase 3" Q9Y6K5 12 112938051-112976460 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" "Nucleotidyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 26.2" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 64.1;Esophageal basal cells: 32.9;Esophageal suprabasal cells: 38.4;Extravillous trophoblasts: 35.9;Foveolar cells: 46.2;Ocular epithelial cells: 35.5;Urothelial cells: 56.4" "Cell type enriched" "Detected in many" 4 "endothelial cell: 49.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 15.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "HPA041253, HPA041372" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" Yes No "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 18 "Nucleoplasm, Cytosol" "Plasma membrane" "HPA041253: , HPA041372: " "unprognostic (9.88e-2)" "unprognostic (1.29e-1)" "unprognostic (3.44e-2)" "unprognostic (1.39e-1)" "unprognostic (1.10e-1)" "unprognostic (3.48e-2)" "unprognostic (8.78e-2)" "unprognostic (3.78e-2)" "unprognostic (1.25e-1)" "unprognostic (3.32e-1)" "unprognostic (1.13e-3)" "unprognostic (2.11e-1)" "unprognostic (1.17e-1)" "unprognostic (5.84e-2)" "unprognostic (1.53e-2)" "unprognostic (1.73e-2)" "unprognostic (3.43e-2)" "unprognostic (3.30e-2)" "unprognostic (1.27e-1)" "unprognostic (3.95e-1)" "unprognostic (1.86e-1)" "potential prognostic unfavorable (6.47e-5)" "unprognostic (3.06e-3)" "unprognostic (9.59e-2)" "unprognostic (3.68e-2)" "unprognostic (5.76e-3)" "unprognostic (2.17e-2)" "unprognostic (8.94e-2)" "unprognostic (7.91e-2)" "unprognostic (4.32e-2)" "unprognostic (2.54e-2)" OASL "OASL1, p59OASL, TRIP14" ENSG00000135114 "2'-5'-oligoadenylate synthetase like" Q15646 12 121017763-121039246 "Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 33.7;stomach 1: 21.0" "Cell type enhanced" "Detected in many" "Colonocytes: 64.6;Esophageal apical cells: 110.1;Esophageal suprabasal cells: 32.2;Foveolar cells: 201.5;Goblet cells: 41.5;monocytes: 34.8;Neutrophils: 36.1;T-cells: 48.3;Urothelial cells: 78.6" "Group enriched" "Detected in some" 6 "endothelial cell: 5.4;leukocyte: 21.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 133.3" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "pancreatic cancer: 43.2" "Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA001474 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 20: Non-specific - Transcription regulation" 47 "Nucleoplasm, Cytosol" "HPA001474: " "unprognostic (2.85e-2)" "unprognostic (1.16e-1)" "unprognostic (2.40e-1)" "unprognostic (2.12e-1)" "unprognostic (1.47e-1)" "unprognostic (2.97e-1)" "unprognostic (2.41e-1)" "unprognostic (8.61e-2)" "unprognostic (2.42e-1)" "unprognostic (2.35e-1)" "unprognostic (3.39e-3)" "unprognostic (8.55e-3)" "unprognostic (5.64e-2)" "unprognostic (1.11e-1)" "unprognostic (3.65e-3)" "unprognostic (6.71e-3)" "unprognostic (1.47e-1)" "unprognostic (6.38e-2)" "unprognostic (6.98e-2)" "unprognostic (2.03e-1)" "unprognostic (2.07e-1)" "potential prognostic unfavorable (6.23e-4)" "unprognostic (4.10e-2)" "unprognostic (1.19e-1)" "unprognostic (1.21e-1)" "unprognostic (5.50e-2)" "unprognostic (2.83e-2)" "unprognostic (1.02e-1)" "unprognostic (2.19e-2)" "unprognostic (1.50e-1)" "unprognostic (5.81e-3)" OAT HOGA ENSG00000065154 "Ornithine aminotransferase" P04181 10 124397303-124418976 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Aminotransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 736.4" "Cell type enhanced" "Detected in all" "Breast lactating cells: 381.4;Enterocytes: 1241.2;Respiratory deuterosomal cells: 377.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033576, HPA040098, HPA064742" Enhanced Supported Nucleoplasm,Mitochondria NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 27: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 1: Enterocytes - Absorption and Digestion" 20 Mitochondria Nucleoplasm "CAB033576: , HPA040098: , HPA064742: " "unprognostic (8.28e-2)" "unprognostic (1.01e-2)" "unprognostic (6.11e-2)" "unprognostic (3.40e-2)" "unprognostic (1.43e-1)" "unprognostic (1.64e-1)" "unprognostic (2.09e-1)" "unprognostic (1.03e-2)" "unprognostic (1.13e-1)" "unprognostic (2.15e-1)" "potential prognostic favorable (3.63e-6)" "unprognostic (7.76e-2)" "unprognostic (1.58e-1)" "unprognostic (2.35e-1)" "unprognostic (2.43e-2)" "unprognostic (1.61e-2)" "unprognostic (2.03e-1)" "unprognostic (1.29e-1)" "unprognostic (3.34e-2)" "unprognostic (2.62e-3)" "potential prognostic unfavorable (3.03e-4)" "unprognostic (1.85e-1)" "unprognostic (1.02e-1)" "unprognostic (8.04e-2)" "unprognostic (4.21e-1)" "unprognostic (2.14e-1)" "unprognostic (4.05e-1)" "unprognostic (9.14e-2)" "unprognostic (1.78e-1)" "unprognostic (4.60e-2)" "unprognostic (2.11e-2)" OAZ1 "AZ1, AZI, MGC138338, OAZ" ENSG00000104904 "Ornithine decarboxylase antizyme 1" P54368 19 2269509-2273490 "Plasma proteins, Predicted intracellular proteins" "Polyamine biosynthesis, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 1171.0;Kupffer cells: 1125.3;Megakaryocytes: 1607.2;Neutrophils: 1103.7;Platelets: 6103.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009291 Uncertain Approved "Vesicles,Centriolar satellite" NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 47: Platelets - Hemostasis" 6 Vesicles "Centriolar satellite" "HPA009291: " "unprognostic (1.12e-2)" "unprognostic (6.13e-2)" "unprognostic (1.17e-1)" "unprognostic (1.56e-1)" "unprognostic (4.81e-2)" "unprognostic (3.59e-2)" "unprognostic (4.56e-2)" "unprognostic (2.38e-1)" "unprognostic (1.55e-1)" "unprognostic (8.27e-3)" "unprognostic (1.14e-1)" "unprognostic (4.21e-2)" "unprognostic (1.32e-1)" "potential prognostic unfavorable (7.29e-6)" "unprognostic (1.51e-2)" "unprognostic (2.59e-1)" "unprognostic (9.80e-2)" "unprognostic (3.94e-2)" "unprognostic (1.63e-1)" "unprognostic (1.57e-1)" "unprognostic (2.29e-1)" "unprognostic (1.17e-2)" "unprognostic (2.50e-1)" "unprognostic (4.39e-2)" "unprognostic (1.61e-1)" "unprognostic (2.08e-1)" "unprognostic (1.74e-1)" "unprognostic (1.67e-1)" "unprognostic (1.07e-2)" "unprognostic (4.05e-1)" "unprognostic (2.72e-2)" OAZ2 ENSG00000180304 "Ornithine decarboxylase antizyme 2" O95190 15 64687573-64703281 "Predicted intracellular proteins" "Polyamine biosynthesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 399.7;Neutrophils: 289.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 420.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Liver - Hepatocytes, Minor Salivary Gland - Endothelial cells, Prostate - Fibroblasts, Skeletal muscle - Skeletal myocytes, Spleen - Macrophages, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047694 Uncertain Approved "Golgi apparatus" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 103: Non-specific - Basic cellular processes" 6 "Golgi apparatus" "HPA047694: " "unprognostic (2.91e-2)" "unprognostic (1.79e-2)" "unprognostic (7.39e-2)" "unprognostic (1.68e-1)" "unprognostic (1.41e-2)" "unprognostic (3.76e-1)" "unprognostic (1.72e-2)" "unprognostic (4.28e-2)" "unprognostic (1.49e-2)" "unprognostic (1.10e-1)" "validated prognostic favorable (6.66e-7)" "validated prognostic favorable (7.96e-5)" "unprognostic (2.57e-2)" "unprognostic (1.24e-1)" "unprognostic (2.94e-1)" "unprognostic (1.82e-1)" "unprognostic (5.26e-1)" "unprognostic (1.94e-1)" "unprognostic (1.24e-1)" "unprognostic (4.97e-2)" "unprognostic (4.31e-2)" "unprognostic (1.93e-2)" "unprognostic (2.04e-2)" "unprognostic (7.24e-2)" "unprognostic (1.77e-3)" "unprognostic (2.77e-1)" "unprognostic (2.69e-2)" "unprognostic (2.91e-1)" "unprognostic (1.85e-1)" "unprognostic (1.55e-1)" "unprognostic (2.56e-1)" OAZ3 ENSG00000143450 "Ornithine decarboxylase antizyme 3" Q9UMX2 1 151762899-151771334 "Predicted intracellular proteins" "Polyamine biosynthesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 15 "testis: 224.4" "Cell type enriched" "Detected in many" 7 "Late spermatids: 21908.7" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 31.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA030136, HPA045808" Supported "Nucleoplasm,Mid piece,Principal piece" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 79: Testis - Spermatogenesis" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 45: Non-specific - Nuclear processes" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 12 Nucleoplasm "Mid piece, Principal piece" "HPA030136: , HPA045808: " "unprognostic (2.41e-1)" "unprognostic (1.24e-1)" "unprognostic (2.43e-1)" "unprognostic (2.61e-3)" "unprognostic (2.48e-1)" "unprognostic (1.05e-1)" "unprognostic (4.68e-2)" "unprognostic (1.41e-2)" "potential prognostic unfavorable (3.30e-4)" "unprognostic (3.65e-2)" "unprognostic (1.27e-1)" "unprognostic (1.77e-1)" "unprognostic (4.91e-3)" "unprognostic (8.62e-3)" "unprognostic (2.02e-1)" "unprognostic (3.56e-1)" "unprognostic (6.44e-2)" "unprognostic (3.06e-1)" "potential prognostic favorable (8.55e-6)" "unprognostic (3.08e-2)" "unprognostic (3.04e-1)" "unprognostic (5.60e-1)" "unprognostic (3.10e-3)" "unprognostic (3.85e-1)" "unprognostic (4.61e-2)" "unprognostic (3.84e-1)" "unprognostic (1.91e-1)" "unprognostic (1.90e-1)" "unprognostic (1.58e-1)" OBI1 "C13orf7, FLJ13449, RNF219" ENSG00000152193 "ORC ubiquitin ligase 1" Q5W0B1 13 78614289-78659155 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034785, HPA034786" Enhanced Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 19: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 49 "Nucleoplasm, Nuclear bodies" Cytosol "HPA034785: , HPA034786: " "unprognostic (4.00e-2)" "unprognostic (2.96e-2)" "unprognostic (3.29e-3)" "unprognostic (4.53e-2)" "unprognostic (1.82e-1)" "unprognostic (1.45e-1)" "unprognostic (1.27e-1)" "unprognostic (1.37e-2)" "unprognostic (1.76e-3)" "validated prognostic favorable (6.82e-4)" "validated prognostic favorable (1.27e-4)" "unprognostic (3.76e-1)" "potential prognostic unfavorable (6.85e-4)" "unprognostic (1.05e-1)" "unprognostic (1.82e-2)" "unprognostic (3.51e-1)" "unprognostic (3.85e-2)" "unprognostic (5.59e-2)" "unprognostic (8.65e-2)" "unprognostic (1.05e-1)" "unprognostic (1.14e-1)" "unprognostic (9.45e-3)" "unprognostic (1.34e-1)" "unprognostic (1.47e-1)" "unprognostic (6.65e-2)" "unprognostic (2.10e-1)" "unprognostic (1.92e-1)" "unprognostic (2.79e-1)" "unprognostic (1.18e-1)" OBP2A "hOBPIIa, LCN13, OBP" ENSG00000122136 "Odorant binding protein 2A" Q9NY56 9 135546126-135549969 "Predicted secreted proteins" "Olfaction, Sensory transduction, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "fallopian tube: 23.4" "Cell type enriched" "Detected in some" 11 "Fallopian secretory cells: 51.7" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Ovary Serous Cystadenocarcinoma (TCGA): 44.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 1.8;thyroid cancer: 2.7" "Skin - Eccrine sweat gland cells" HPA055955 Uncertain "Secreted in other tissues" Transport NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" "HPA055955: " "unprognostic (1.45e-1)" "unprognostic (1.08e-1)" "unprognostic (3.66e-2)" "unprognostic (2.06e-2)" "unprognostic (1.00e-2)" "unprognostic (5.92e-2)" "unprognostic (2.33e-2)" OBP2B "hOBPIIb, LCN14" ENSG00000171102 "Odorant binding protein 2B" Q9NPH6 9 133205277-133209250 "Predicted secreted proteins" "Olfaction, Sensory transduction, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skin 1: 2.4;testis: 9.4" "Cell type enhanced" "Detected in some" "Breast hormone-responsive cells: 4.6;Breast myoepithelial cells: 2.6;Breast secretory cells: 13.5;Epididymal efferent duct absorptive cells: 3.8;Epididymal principal cells: 5.3;Fallopian secretory cells: 7.1;Granulosa cells: 6.5;Late spermatids: 1.8;Paneth cells: 3.9;Sertoli cells: 13.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Breast Invasive Carcinoma (TCGA): 3.4;Uterine Corpus Endometrial Carcinoma (TCGA): 4.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Eccrine sweat gland cells" "Secreted in other tissues" Transport NA NA "Cluster 47: Testis - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" "unprognostic (6.22e-2)" "unprognostic (2.74e-1)" "unprognostic (3.27e-2)" "unprognostic (2.87e-2)" "unprognostic (4.99e-2)" OBSCN "ARHGEF30, KIAA1556, KIAA1639, UNC89" ENSG00000154358 "Obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF" Q5VST9 1 228208044-228378876 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Differentiation "Calmodulin-binding, Developmental protein, Kinase, Muscle protein, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "skeletal muscle: 320.2;tongue: 105.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 1084.5;Myonuclei: 2490.1;Thymic myoid cells: 484.0" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 133.0;medium spiny neuron: 105.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Liver - Hepatic stellate cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA021186, HPA065801" Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 54: Immune cells - T cell receptor" "Cluster 15: Kidney cancer - Membrane components" "Cluster 55: Myocytes - Oxidative muscle function" 6 "Plasma membrane, Cytosol" "HPA021186: , HPA065801: " "unprognostic (5.60e-2)" "unprognostic (1.76e-1)" "unprognostic (1.42e-1)" "unprognostic (1.49e-3)" "unprognostic (8.81e-2)" "unprognostic (4.86e-1)" "unprognostic (3.59e-1)" "unprognostic (4.73e-1)" "unprognostic (4.22e-2)" "unprognostic (8.50e-2)" "unprognostic (6.31e-2)" "unprognostic (8.47e-2)" "unprognostic (2.08e-2)" "unprognostic (1.71e-1)" "unprognostic (1.83e-3)" "unprognostic (5.19e-3)" "unprognostic (7.68e-2)" "unprognostic (3.23e-1)" "unprognostic (3.68e-3)" "unprognostic (1.27e-1)" "unprognostic (1.11e-2)" "unprognostic (4.34e-2)" "unprognostic (1.14e-2)" "unprognostic (1.43e-1)" "unprognostic (1.70e-1)" "unprognostic (1.86e-3)" OBSL1 KIAA0657 ENSG00000124006 "Obscurin like cytoskeletal adaptor 1" O75147 2 219550728-219571859 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 329.2" "Group enriched" "Detected in many" 12 "Early spermatids: 1009.4;Late primary spermatocytes: 1806.2;Late spermatids: 2928.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "basophil: 4.4;plasmacytoid DC: 1.3" "Group enriched" "Detected in many" 11 "dendritic cells: 1.3;granulocytes: 4.4" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Pituitary gland - Undifferentiated cells (Pituitary gland), Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036404, HPA036405" Approved Approved Centrosome NA NA "Cluster 75: Ovary - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 78 Centrosome "HPA036404: , HPA036405: " "unprognostic (1.45e-2)" "unprognostic (1.09e-2)" "unprognostic (6.91e-2)" "unprognostic (1.89e-2)" "unprognostic (6.89e-2)" "unprognostic (7.98e-2)" "unprognostic (2.10e-3)" "unprognostic (1.58e-2)" "unprognostic (3.23e-3)" "unprognostic (1.12e-1)" "unprognostic (2.86e-2)" "potential prognostic favorable (1.15e-4)" "unprognostic (1.03e-1)" "unprognostic (2.44e-2)" "unprognostic (8.80e-2)" "unprognostic (2.10e-2)" "unprognostic (1.74e-1)" "unprognostic (3.11e-1)" "unprognostic (9.60e-2)" "unprognostic (1.68e-1)" "unprognostic (1.56e-1)" "unprognostic (2.13e-2)" "unprognostic (6.34e-2)" "unprognostic (1.21e-1)" "unprognostic (2.63e-1)" "unprognostic (1.20e-2)" "unprognostic (3.25e-3)" "unprognostic (5.60e-3)" "unprognostic (5.06e-2)" "unprognostic (2.26e-1)" "unprognostic (7.50e-2)" OC90 PLA2L ENSG00000253117 "Otoconin 90" Q02509 8 132024216-132059382 "Predicted secreted proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "deep-layer intratelencephalic: 1.3;thalamic excitatory: 2.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Sebaceous gland cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Secreted in other tissues" "No annotated function" NA NA "Cluster 34: Testis cancer - Unknown function" "Cluster 109: Neurons - Neuronal signaling" OCA2 "BEY, BEY1, BEY2, D15S12, EYCL, EYCL2, EYCL3, P" ENSG00000104044 "OCA2 melanosomal transmembrane protein" Q04671 15 27754875-28099315 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Albinism, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "choroid plexus: 28.0" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 805.2;Ependymal cells: 184.1;Melanocytes: 242.2;Retinal pigment epithelial cells: 98.0" "Cell type enriched" "Detected in many" 4 "choroid plexus epithelial cell: 739.3" "Cancer enriched" "Detected in many" 13 "Skin Cutaneous Melanoma (TCGA): 27.2" "Region enriched" "Detected in many" 10 "choroid plexus: 63.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 11 "skin cancer: 24.6" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Skin - Melanocytes, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA036402 Approved "Plasma membrane,Cytosol" NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 101: Choroid plexus epithelial cells - Ion transport" "Plasma membrane" Cytosol "HPA036402: " "unprognostic (3.03e-2)" "unprognostic (5.54e-2)" "unprognostic (1.66e-1)" "unprognostic (6.83e-2)" "unprognostic (2.69e-1)" "unprognostic (8.26e-2)" "unprognostic (1.45e-1)" "unprognostic (2.31e-1)" "unprognostic (1.73e-2)" "unprognostic (4.32e-1)" "unprognostic (2.87e-2)" "unprognostic (8.78e-2)" OCEL1 FLJ22709 ENSG00000099330 "Occludin/ELL domain containing 1" Q9H607 19 17226213-17229219 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 75.7" "Cell type enhanced" "Detected in many" "Enterocytes: 124.7;Epididymal efferent duct ciliated cells: 78.5;Fallopian tube ciliated cells: 126.8;Hepatocytes: 107.0;Respiratory ciliated cells: 79.5;Syncytiotrophoblasts: 137.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042070, HPA043223" Uncertain Approved "Golgi apparatus" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 70: Non-specific - Protein processing" "Cluster 45: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" "Golgi apparatus" "HPA042070: , HPA043223: " "unprognostic (6.73e-3)" "unprognostic (1.83e-1)" "unprognostic (2.65e-1)" "potential prognostic favorable (4.46e-4)" "unprognostic (1.32e-1)" "unprognostic (9.09e-2)" "unprognostic (9.00e-3)" "unprognostic (2.17e-2)" "unprognostic (1.15e-1)" "unprognostic (2.10e-1)" "unprognostic (1.33e-3)" "unprognostic (9.50e-2)" "unprognostic (6.20e-3)" "potential prognostic favorable (5.19e-4)" "unprognostic (4.98e-2)" "unprognostic (1.80e-1)" "unprognostic (1.17e-1)" "potential prognostic unfavorable (1.57e-5)" "unprognostic (1.54e-2)" "unprognostic (1.17e-1)" "unprognostic (1.96e-3)" "unprognostic (4.32e-2)" "unprognostic (1.39e-1)" "unprognostic (3.80e-1)" "unprognostic (1.00e-2)" "unprognostic (2.21e-3)" "unprognostic (7.76e-2)" "unprognostic (3.58e-1)" "unprognostic (1.33e-1)" "unprognostic (2.08e-1)" "unprognostic (4.13e-1)" OCIAD1 "Asrij, FLJ20455, OCIA, TPA018" ENSG00000109180 "OCIA domain containing 1" Q9NX40 4 48805212-48861817 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044803, HPA073865" Approved Approved Vesicles NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 76: Non-specific - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 98: Neurons - Neurotransmission & signaling" 56 Vesicles "HPA044803: , HPA073865: " "unprognostic (9.82e-2)" "unprognostic (1.81e-1)" "potential prognostic unfavorable (3.59e-4)" "unprognostic (1.63e-2)" "unprognostic (1.20e-1)" "potential prognostic favorable (9.37e-4)" "unprognostic (1.49e-1)" "unprognostic (1.60e-1)" "unprognostic (2.71e-2)" "unprognostic (3.46e-3)" "validated prognostic favorable (2.56e-6)" "validated prognostic favorable (2.78e-4)" "unprognostic (2.92e-1)" "unprognostic (1.60e-1)" "unprognostic (5.86e-2)" "unprognostic (1.81e-3)" "unprognostic (7.12e-2)" "unprognostic (1.27e-1)" "unprognostic (1.89e-1)" "unprognostic (1.17e-1)" "unprognostic (1.84e-2)" "unprognostic (8.41e-2)" "unprognostic (3.55e-2)" "unprognostic (1.72e-1)" "unprognostic (6.44e-2)" "unprognostic (1.39e-1)" "unprognostic (2.47e-1)" "unprognostic (1.89e-1)" "unprognostic (2.24e-2)" "unprognostic (1.68e-1)" "unprognostic (2.59e-2)" OCIAD2 MGC45416 ENSG00000145247 "OCIA domain containing 2" Q56VL3 4 48885019-48906937 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 144.9" "Cell type enhanced" "Detected in many" "Colonocytes: 325.6;Enterocytes: 634.3;Epididymal efferent duct absorptive cells: 616.6;Gastric chief cells: 314.5;Gastric progenitor cells: 483.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040979, HPA041090" Enhanced Enhanced Mitochondria No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 29: Forebrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 2 Mitochondria "HPA040979: , HPA041090: " "unprognostic (1.68e-1)" "unprognostic (7.48e-2)" "unprognostic (1.41e-1)" "unprognostic (9.91e-2)" "unprognostic (5.14e-2)" "unprognostic (9.29e-2)" "unprognostic (1.71e-2)" "unprognostic (1.82e-3)" "unprognostic (2.28e-2)" "unprognostic (4.70e-2)" "potential prognostic favorable (2.01e-6)" "unprognostic (4.03e-3)" "potential prognostic favorable (2.26e-6)" "unprognostic (7.37e-2)" "potential prognostic favorable (3.40e-4)" "unprognostic (2.79e-3)" "unprognostic (3.11e-3)" "unprognostic (8.99e-2)" "unprognostic (4.01e-2)" "unprognostic (1.14e-2)" "unprognostic (8.46e-2)" "unprognostic (1.35e-2)" "unprognostic (2.80e-1)" "unprognostic (4.70e-2)" "unprognostic (9.16e-3)" "unprognostic (1.13e-1)" "unprognostic (2.03e-1)" "unprognostic (1.99e-1)" "unprognostic (1.90e-1)" "unprognostic (1.16e-1)" "unprognostic (9.79e-2)" OCLN PPP1R115 ENSG00000197822 Occludin Q16625 5 69492292-69558104 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 29.4" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 62.6;Distal convoluted tubule cells: 134.9;Loop of henle epithelial cells: 95.8;Papillary tip epithelial cells: 80.2;Proximal tubule cells: 45.1;Renal collecting duct intercalated cells: 111.2;Renal collecting duct principal cells: 52.3;Renal connecting tubule cells: 75.7;Urothelial cells: 49.1" "Group enriched" "Detected in many" 8 "choroid plexus epithelial cell: 59.7;endothelial cell: 113.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 2.6" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005933, CAB013075, CAB068212, CAB068213, CAB068214" Enhanced Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 60: Stomach - Digestion" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 53 "Plasma membrane, Cell Junctions" "CAB013075: , CAB068212: , CAB068213: , CAB068214: , HPA005933: " "unprognostic (2.16e-1)" "unprognostic (3.24e-2)" "unprognostic (9.66e-2)" "unprognostic (1.65e-1)" "unprognostic (5.38e-2)" "unprognostic (4.71e-2)" "unprognostic (6.53e-2)" "unprognostic (2.35e-1)" "unprognostic (3.16e-2)" "unprognostic (2.11e-1)" "unprognostic (3.75e-3)" "unprognostic (1.17e-2)" "unprognostic (7.05e-3)" "unprognostic (1.13e-1)" "unprognostic (8.98e-3)" "potential prognostic favorable (2.01e-4)" "unprognostic (3.45e-2)" "unprognostic (1.12e-1)" "unprognostic (4.59e-1)" "unprognostic (2.28e-1)" "unprognostic (3.07e-2)" "unprognostic (1.90e-1)" "unprognostic (2.39e-1)" "unprognostic (1.88e-1)" "unprognostic (2.41e-1)" "unprognostic (2.39e-1)" "unprognostic (9.97e-2)" "unprognostic (2.09e-1)" "unprognostic (3.11e-1)" "unprognostic (1.18e-1)" "unprognostic (2.68e-2)" OCM OCM1 ENSG00000122543 Oncomodulin P0CE72 7 5879827-5886363 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.7" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 2.3;Early spermatids: 2.8;Kupffer cells: 3.1;Late primary spermatocytes: 2.6;Late spermatids: 3.6;Medullary thymic epithelial cells: 2.4;Retinal horizontal cells: 4.0;Undifferentiated spermatogonia: 2.4" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "T-reg: 2.7" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "HPA046422, HPA052483" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 15: Non-specific - Transcription" "Cluster 11: Neuronal - Sensory perception" "Cluster 9: T-cells - Adaptive immunity: Regulation" 3 "Plasma membrane" Cytosol "HPA046422: , HPA052483: " "unprognostic (3.03e-1)" "unprognostic (1.30e-1)" OCM2 ENSG00000135175 "Oncomodulin 2" P0CE71 7 97984687-97991169 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 9 "Retinal ganglion cells: 7.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046422, HPA052483" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 15: Kidney cancer - Membrane components" "Cluster 82: Dendritic cells - Antigen presentation" "Plasma membrane" Cytosol "HPA046422: , HPA052483: " OCRL "Dent-2, OCRL1" ENSG00000122126 "OCRL inositol polyphosphate-5-phosphatase" Q01968 X 129539849-129592561 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cilium biogenesis/degradation, Lipid metabolism" Hydrolase "Cataract, Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 97.3;Sertoli cells: 88.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "classical monocyte: 1.0;intermediate monocyte: 1.1;myeloid DC: 1.2;non-classical monocyte: 3.7" "Group enriched" "Detected in many" 8 "dendritic cells: 1.2;monocytes: 3.7" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Smooth muscle cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012495 Approved Approved "Microtubules,Primary cilium,Centriolar satellite,Basal body,Cytosol" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 65: Brain - Transcription" "Cluster 23: Choroid plexus - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 18: Adrenal cortex cells - Steroidogensis" 42 "Microtubules, Primary cilium" "Centriolar satellite, Basal body, Cytosol" "HPA012495: " "unprognostic (8.08e-3)" "potential prognostic unfavorable (2.08e-6)" "unprognostic (6.32e-2)" "unprognostic (1.95e-2)" "unprognostic (3.15e-2)" "unprognostic (3.42e-1)" "unprognostic (5.30e-2)" "potential prognostic favorable (6.08e-5)" "unprognostic (1.53e-1)" "unprognostic (2.23e-1)" "potential prognostic favorable (1.14e-5)" "unprognostic (1.29e-1)" "unprognostic (2.93e-2)" "unprognostic (1.04e-1)" "unprognostic (1.16e-1)" "unprognostic (3.98e-2)" "unprognostic (1.98e-2)" "unprognostic (1.73e-1)" "unprognostic (2.28e-1)" "unprognostic (1.98e-2)" "unprognostic (1.60e-1)" "unprognostic (3.98e-1)" "unprognostic (3.60e-1)" "unprognostic (3.11e-1)" "unprognostic (1.52e-3)" "unprognostic (1.80e-1)" "unprognostic (2.82e-2)" "unprognostic (2.15e-1)" "unprognostic (3.01e-1)" "unprognostic (5.91e-2)" "unprognostic (4.83e-3)" OCSTAMP "C20orf123, dJ257E24.3" ENSG00000149635 "Osteoclast stimulatory transmembrane protein" Q9BR26 20 46540946-46550654 "Predicted membrane proteins, Transporters" Differentiation "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Late primary spermatocytes: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Myeloma: 4.7" "Kidney - Proximal tubular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA031116 Uncertain NA NA "Cluster 51: Myeloma - Immunoglobulins" "Cluster 82: Dendritic cells - Antigen presentation" "HPA031116: " ODAD1 "CCDC114, CILD20, FLJ32926" ENSG00000105479 "Outer dynein arm docking complex subunit 1" Q96M63 19 48296457-48321971 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "choroid plexus: 27.5;fallopian tube: 24.0;testis: 21.1" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 115.2;Endometrial ciliated cells: 95.5;Ependymal cells: 162.8;Epididymal efferent duct ciliated cells: 45.3;Fallopian tube ciliated cells: 124.7;Late primary spermatocytes: 31.2;Respiratory ciliated cells: 152.4;Respiratory deuterosomal cells: 25.9" "Group enriched" "Detected in some" 43 "choroid plexus epithelial cell: 126.7;ependymal cell: 177.1" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 5.6" "Region enhanced" "Detected in all" "choroid plexus: 61.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 2.7" "Lung - Respiratory ciliated cells, Testis - Early spermatids" HPA042524 Approved Supported "Connecting piece,Mid piece,Principal piece" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" 11 "Mid piece" "Connecting piece, Principal piece" "HPA042524: " "unprognostic (7.65e-2)" "unprognostic (4.78e-2)" "unprognostic (6.17e-3)" "unprognostic (6.62e-2)" "unprognostic (3.85e-2)" "potential prognostic favorable (6.01e-4)" "unprognostic (1.11e-1)" "unprognostic (3.10e-1)" ODAD2 "ARMC4, CILD23, DKFZP434P1735, FLJ10376, FLJ10817, gudu" ENSG00000169126 "Outer dynein arm docking complex subunit 2" Q5T2S8 10 27775186-27999079 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 21.8;testis: 38.0" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 183.9;Early spermatids: 399.1;Endometrial ciliated cells: 204.4;Ependymal cells: 572.7;Epididymal efferent duct ciliated cells: 182.2;Fallopian tube ciliated cells: 353.1;Gonadotrophs: 211.7;Late primary spermatocytes: 352.9;Respiratory ciliated cells: 653.3" "Group enriched" "Detected in many" 20 "choroid plexus epithelial cell: 188.9;ependymal cell: 624.0" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 4.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 7.1" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal cortex cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA037829 Enhanced Approved "Acrosome,Principal piece,End piece" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 11: Neuronal - Sensory perception" "Cluster 34: Ciliated cells - Cilia assembly & function" 11 "End piece" "Acrosome, Principal piece" "HPA037829: " "unprognostic (4.67e-1)" "unprognostic (1.20e-1)" "unprognostic (3.54e-2)" "unprognostic (1.60e-1)" "unprognostic (1.79e-1)" "unprognostic (1.47e-2)" "unprognostic (1.40e-1)" "unprognostic (6.23e-2)" "unprognostic (5.85e-2)" "unprognostic (2.19e-2)" ODAD3 "CCDC151, MGC20983, ODA10" ENSG00000198003 "Outer dynein arm docking complex subunit 3" A5D8V7 19 11420604-11435782 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 13.9;parathyroid gland: 9.2;testis: 10.3" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 55.2;Decidual stromal cells: 47.8;Endometrial ciliated cells: 26.4;Ependymal cells: 55.7;Epididymal efferent duct ciliated cells: 40.7;Fallopian tube ciliated cells: 54.2;Kupffer cells: 109.7;Late primary spermatocytes: 24.6;Müller glia: 33.8;Respiratory ciliated cells: 91.1" "Group enriched" "Detected in many" 4 "choroid plexus epithelial cell: 39.1;ependymal cell: 59.5" "Cancer enriched" "Detected in many" 6 "Kidney Chromophobe (TCGA): 32.0" "Region enhanced" "Detected in all" "choroid plexus: 23.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells, Skin - Eccrine sweat gland cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA054626 Enhanced Approved "Principal piece" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 107: Ciliated cells - Cilia assembly & function" 20 "Principal piece" "HPA054626: " "unprognostic (2.22e-1)" "unprognostic (1.76e-2)" "unprognostic (4.62e-3)" "unprognostic (5.18e-2)" "unprognostic (7.70e-2)" "unprognostic (1.18e-1)" "unprognostic (2.66e-1)" "unprognostic (2.42e-1)" "unprognostic (6.52e-2)" "unprognostic (4.93e-2)" "unprognostic (4.56e-2)" "unprognostic (2.04e-1)" "unprognostic (2.71e-1)" "unprognostic (1.81e-1)" ODAD4 "DKFZP434H0115, TTC25" ENSG00000204815 "Outer dynein arm docking complex subunit 4" Q96NG3 17 41930617-41966503 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "choroid plexus: 11.5;fallopian tube: 16.0;testis: 22.5" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 77.8;Early spermatids: 214.6;Endometrial ciliated cells: 97.9;Ependymal cells: 109.8;Epididymal efferent duct ciliated cells: 109.1;Fallopian tube ciliated cells: 195.2;Late primary spermatocytes: 307.9;Respiratory ciliated cells: 268.9" "Group enriched" "Detected in all" 4 "choroid plexus epithelial cell: 66.8;ependymal cell: 112.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Adipose progenitor cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA023908 Enhanced Uncertain "Centrosome,Basal body,Acrosome,Mid piece,Principal piece,End piece" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 47: Leukemia - Hemostasis" "Cluster 107: Ciliated cells - Cilia assembly & function" 7 "Centrosome, Basal body" "Acrosome, Mid piece, Principal piece, End piece" "HPA023908: " "unprognostic (5.29e-2)" "unprognostic (8.55e-2)" "unprognostic (4.53e-2)" "potential prognostic favorable (1.41e-4)" "unprognostic (4.79e-2)" "unprognostic (8.42e-2)" "unprognostic (1.74e-2)" "unprognostic (2.41e-1)" "unprognostic (2.34e-2)" "unprognostic (2.42e-3)" "unprognostic (7.88e-2)" "unprognostic (1.64e-1)" "unprognostic (1.45e-1)" ODAM "APin, FLJ20513" ENSG00000109205 "Odontogenic, ameloblast associated" A1E959 4 70195725-70204576 "Cancer-related genes, Predicted intracellular proteins" Biomineralization "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 34 "salivary gland: 320.4" "Cell type enhanced" "Detected in some" "Breast lactating cells: 101.6;Lacrimal acinar cells: 223.7;Parietal cells: 251.0;Salivary acinar cells: 335.7;Salivary myoepithelial cells: 74.3;Submucosal glandular cells: 102.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 16.3" "Region enhanced" "Detected in some" "medulla oblongata: 2.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 8.0;colorectal cancer: 8.7;Gastric cancer: 21.4" "Colon - Colon enteroendocrine cells, Stomach - Parietal cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA036279, HPA036543, HPA070297" Supported Nucleoplasm,Cytosol "Intracellular and membrane" Other NA NA "Cluster 82: Salivary gland - Secretion" "Cluster 46: Brainstem - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 11 Nucleoplasm Cytosol "HPA036279: , HPA036543: , HPA070297: " "unprognostic (8.76e-2)" "unprognostic (6.96e-2)" "unprognostic (4.07e-1)" "unprognostic (1.55e-1)" "unprognostic (4.23e-2)" "unprognostic (2.93e-3)" "unprognostic (5.58e-2)" "unprognostic (5.01e-1)" "unprognostic (1.49e-1)" "unprognostic (1.35e-2)" "unprognostic (7.88e-2)" "unprognostic (2.06e-1)" "unprognostic (2.40e-1)" "unprognostic (2.61e-2)" "unprognostic (1.93e-1)" "unprognostic (2.32e-1)" "unprognostic (1.83e-1)" "unprognostic (1.94e-1)" "unprognostic (3.17e-1)" ODAPH "AI2A4, C4orf26, FLJ23657" ENSG00000174792 "Odontogenesis associated phosphoprotein" Q17RF5 4 75556048-75565871 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Amelogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "placenta: 5.5" "Cell type enhanced" "Detected in some" "Early spermatids: 3.2;Extravillous trophoblasts: 13.7;Late primary spermatocytes: 4.1;Migrating cytotrophoblasts: 7.2;Oligodendrocytes: 3.0;Plasma cells: 9.3;Syncytiotrophoblasts: 34.6" "Cell type enhanced" "Detected in some" "oligodendrocyte: 3.9" "Cancer enhanced" "Detected in some" "Bladder Urothelial Carcinoma (TCGA): 5.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 34 "basophil: 10.7" "Lineage enriched" "Detected in single" 34 "granulocytes: 10.7" "Cancer enhanced" "Detected in many" "Bladder cancer: 8.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted in other tissues" "No annotated function" NA NA "Cluster 32: Basophils - Transcription" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 30: White matter - Myelination" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." 13 "unprognostic (3.37e-3)" "unprognostic (1.13e-3)" "unprognostic (5.79e-3)" "unprognostic (6.42e-2)" "unprognostic (3.52e-2)" "unprognostic (1.25e-1)" "unprognostic (5.09e-3)" ODC1 ODC ENSG00000115758 "Ornithine decarboxylase 1" P11926 2 10439968-10448327 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Polyamine biosynthesis" "Decarboxylase, Lyase" "Disease variant, FDA approved drug targets, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 556.5;Late primary spermatocytes: 498.0;Late spermatids: 1458.4;Platelets: 972.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001536, CAB035996, HPA075384" Approved Approved "Golgi apparatus,Cytosol" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 39: Testis - Nuclear processes" "Cluster 21: Non-specific - Metabolism" "Cluster 6: Leukemia - Signal transduction" "Cluster 20: Non-specific - Transcription regulation" 7 "Golgi apparatus" Cytosol "CAB035996: , HPA001536: , HPA075384: " "unprognostic (1.73e-1)" "unprognostic (4.14e-1)" "unprognostic (6.59e-3)" "unprognostic (2.74e-1)" "unprognostic (4.51e-2)" "unprognostic (3.78e-2)" "unprognostic (2.87e-1)" "unprognostic (1.13e-2)" "unprognostic (2.95e-1)" "potential prognostic unfavorable (7.62e-4)" "potential prognostic favorable (9.59e-5)" "unprognostic (8.23e-3)" "unprognostic (6.99e-2)" "potential prognostic unfavorable (8.50e-5)" "unprognostic (1.19e-3)" "unprognostic (2.52e-1)" "unprognostic (2.23e-1)" "unprognostic (9.10e-2)" "unprognostic (1.14e-2)" "unprognostic (9.40e-2)" "unprognostic (1.90e-1)" "unprognostic (1.75e-1)" "unprognostic (2.90e-1)" "unprognostic (1.65e-1)" "unprognostic (4.81e-3)" "unprognostic (4.25e-2)" "unprognostic (9.21e-2)" "unprognostic (2.20e-1)" "unprognostic (2.38e-1)" "unprognostic (9.76e-2)" "unprognostic (1.07e-1)" ODF1 "CT133, HSPB10, ODF27, ODFPG, RT7" ENSG00000155087 "Outer dense fiber of sperm tails 1" Q14990 8 102551589-102561018 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 515 "testis: 333.0" "Cell type enhanced" "Detected in some" "Early spermatids: 223.5;Late primary spermatocytes: 108.1;Late spermatids: 586.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA064295 Approved Approved "Connecting piece,Flagellar centriole,Mid piece" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 9 "Connecting piece, Flagellar centriole, Mid piece" "HPA064295: " ODF2 "CT134, ODF84" ENSG00000136811 "Outer dense fiber of sperm tails 2" Q5BJF6 9 128455186-128501292 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 8 "testis: 292.3" "Cell type enriched" "Detected in many" 5 "Late spermatids: 13180.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pituitary gland - Somatotropes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001874, HPA048841" Enhanced Supported "Vesicles,Microtubules,Primary cilium,Centrosome,Basal body,Calyx,Connecting piece,Mid piece,Principal piece" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 47: Testis - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 11 "Primary cilium, Centrosome, Basal body, Connecting piece" "Vesicles, Microtubules, Calyx, Mid piece, Principal piece" "HPA001874: , HPA048841: " "unprognostic (1.26e-1)" "unprognostic (1.37e-1)" "unprognostic (2.10e-1)" "unprognostic (4.50e-2)" "unprognostic (1.39e-1)" "unprognostic (1.22e-2)" "unprognostic (3.17e-1)" "unprognostic (1.37e-1)" "unprognostic (1.27e-1)" "unprognostic (1.49e-1)" "unprognostic (1.60e-3)" "unprognostic (1.85e-2)" "unprognostic (2.31e-1)" "unprognostic (1.93e-3)" "unprognostic (2.54e-2)" "unprognostic (2.59e-2)" "unprognostic (3.75e-3)" "unprognostic (2.05e-1)" "unprognostic (3.77e-2)" "unprognostic (4.00e-1)" "unprognostic (8.84e-2)" "unprognostic (4.17e-2)" "unprognostic (7.22e-2)" "unprognostic (8.45e-3)" "unprognostic (1.14e-1)" "unprognostic (6.62e-2)" "unprognostic (4.18e-2)" "unprognostic (2.09e-2)" "unprognostic (4.34e-2)" "unprognostic (1.30e-1)" "unprognostic (1.94e-2)" ODF2L KIAA1229 ENSG00000122417 "Outer dense fiber of sperm tails 2 like" Q9ULJ1 1 86346824-86396342 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial ciliated cells: 560.5;Ependymal cells: 446.1;Epididymal efferent duct ciliated cells: 324.9;Prostatic club cells: 371.0;Respiratory ciliated cells: 593.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Liver - Vascular endothelial cells, Skeletal muscle - Endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028020, HPA028095, HPA028333" Uncertain NA NA "Cluster 24: Non-specific - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 9: Non-specific - Receptor signaling" "Cluster 37: Non-specific - mRNA processing" "Cluster 9: T-cells - Adaptive immunity: Regulation" 3 "HPA028020: , HPA028095: , HPA028333: " "unprognostic (1.34e-1)" "unprognostic (4.65e-2)" "unprognostic (1.53e-2)" "unprognostic (4.00e-2)" "unprognostic (6.20e-2)" "unprognostic (1.13e-3)" "unprognostic (8.30e-2)" "unprognostic (1.72e-1)" "unprognostic (3.23e-3)" "unprognostic (2.18e-3)" "unprognostic (2.57e-2)" "unprognostic (2.40e-2)" "unprognostic (6.80e-2)" "unprognostic (1.06e-2)" "unprognostic (1.06e-3)" "unprognostic (6.77e-2)" "unprognostic (5.31e-2)" "unprognostic (7.44e-2)" "unprognostic (1.03e-1)" "unprognostic (9.15e-2)" "unprognostic (3.33e-1)" "unprognostic (2.54e-1)" "unprognostic (4.49e-3)" "unprognostic (2.09e-1)" "unprognostic (2.60e-2)" "unprognostic (4.83e-3)" "unprognostic (1.63e-2)" "unprognostic (1.17e-1)" "unprognostic (1.02e-2)" "unprognostic (3.78e-2)" "unprognostic (2.88e-1)" ODF3 "CT135, hSHIPPO, SHIPPO1" ENSG00000177947 "Outer dense fiber of sperm tails 3" Q96PU9 11 196761-200261 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 19 "testis: 9.0" "Group enriched" "Detected in some" 42 "Early spermatids: 89.6;Late primary spermatocytes: 61.1;Late spermatids: 23.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA038919, HPA039241" Enhanced Approved "Mid piece,Principal piece,End piece" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" 4 "End piece" "Mid piece, Principal piece" "HPA038919: , HPA039241: " ODF3B FAP123 ENSG00000177989 "Outer dense fiber of sperm tails 3B" A8MYP8 22 50529710-50532506 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 75.1" "Group enriched" "Detected in many" 4 "Endometrial ciliated cells: 490.5;Epididymal efferent duct ciliated cells: 828.9;Fallopian tube ciliated cells: 1049.9;Late spermatids: 1271.3;Respiratory ciliated cells: 774.0" "Cell type enriched" "Detected in some" 4 "ependymal cell: 197.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 93.9;intermediate monocyte: 82.0;myeloid DC: 56.8;neutrophil: 66.4;non-classical monocyte: 58.2" "Group enriched" "Detected in many" 15 "dendritic cells: 56.8;granulocytes: 66.4;monocytes: 93.9" "Low cancer specificity" "Detected in many" "Breast - T-cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA062837 Enhanced NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 3: Choroid plexus - Cilium" "Cluster 55: Lymphoma - Immune response" "Cluster 107: Ciliated cells - Cilia assembly & function" 8 "HPA062837: " "unprognostic (1.02e-1)" "unprognostic (9.49e-3)" "unprognostic (8.83e-2)" "unprognostic (9.07e-3)" "unprognostic (1.94e-2)" "unprognostic (9.43e-2)" "unprognostic (6.59e-2)" "unprognostic (3.04e-2)" "potential prognostic favorable (3.05e-4)" "unprognostic (1.59e-1)" "potential prognostic unfavorable (3.32e-4)" "unprognostic (1.11e-1)" "unprognostic (1.57e-1)" "unprognostic (4.56e-3)" "unprognostic (2.39e-3)" "unprognostic (1.62e-1)" "unprognostic (4.62e-2)" "unprognostic (4.79e-3)" "unprognostic (1.53e-1)" "unprognostic (1.22e-1)" "unprognostic (2.13e-3)" "unprognostic (1.79e-1)" "potential prognostic unfavorable (8.35e-4)" "unprognostic (1.40e-1)" "unprognostic (1.53e-1)" "unprognostic (1.38e-1)" "unprognostic (7.48e-3)" "unprognostic (3.14e-1)" "unprognostic (2.37e-3)" "unprognostic (6.56e-2)" "unprognostic (3.99e-2)" ODF3L1 MGC48986 ENSG00000182950 "Outer dense fiber of sperm tails 3 like 1" Q8IXM7 15 75724041-75727688 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "testis: 21.7" "Group enriched" "Detected in some" 5 "Early spermatids: 86.9;Late primary spermatocytes: 117.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 47: Testis - Mixed function" "Cluster 2: Neurons - Nucleosome" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 7 "unprognostic (6.38e-2)" "potential prognostic favorable (9.36e-4)" "unprognostic (1.50e-1)" "unprognostic (3.71e-1)" "unprognostic (1.60e-1)" "unprognostic (6.97e-3)" "unprognostic (4.01e-3)" "unprognostic (2.53e-1)" "unprognostic (7.62e-2)" "unprognostic (8.79e-3)" ODF3L2 "C19orf19, FLJ40059" ENSG00000181781 "Outer dense fiber of sperm tails 3 like 2" Q3SX64 19 463346-474983 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 20 "skeletal muscle: 7.7;testis: 22.3" "Cell type enriched" "Detected in some" 8 "Late spermatids: 2265.5" "Cell type enhanced" "Detected in some" "endothelial cell: 1.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA067973 Uncertain Approved "Nucleoli,Flagellar centriole,Mid piece,Principal piece" NA NA "Cluster 67: Testis - Mixed function" "Cluster 18: Non-specific - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 14 "Flagellar centriole" "Nucleoli, Mid piece, Principal piece" "HPA067973: " ODF4 "CT136, OPPO1" ENSG00000184650 "Outer dense fiber of sperm tails 4" Q2M2E3 17 8339840-8346048 "Predicted membrane proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 124 "testis: 12.3" "Cell type enhanced" "Detected in some" "Early primary spermatocytes: 9.5;Early spermatids: 28.5;Esophageal apical cells: 13.6;Late primary spermatocytes: 115.4;Late spermatids: 46.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Low region specificity" "Detected in many" HPA072129 Enhanced Approved "Principal piece" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 20 "Principal piece" "HPA072129: " ODR4 "C1orf27, FLJ20505, odr-4, TTG1" ENSG00000157181 "Odr-4 GPCR localization factor homolog" Q5SWX8 1 186375838-186421378 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015988, HPA031352" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 4 "Nucleoplasm, Plasma membrane" "HPA015988: , HPA031352: " "unprognostic (6.63e-2)" "unprognostic (5.30e-3)" "unprognostic (1.65e-2)" "unprognostic (6.22e-2)" "unprognostic (8.26e-2)" "unprognostic (5.50e-2)" "unprognostic (1.10e-1)" "unprognostic (2.96e-3)" "unprognostic (9.37e-2)" "unprognostic (6.10e-3)" "unprognostic (2.43e-2)" "unprognostic (3.09e-2)" "unprognostic (5.21e-2)" "unprognostic (1.92e-1)" "unprognostic (1.20e-1)" "unprognostic (1.40e-1)" "unprognostic (2.24e-2)" "unprognostic (2.42e-2)" "unprognostic (3.65e-2)" "unprognostic (8.82e-2)" "unprognostic (1.90e-3)" "unprognostic (1.27e-1)" "unprognostic (1.85e-1)" "unprognostic (1.86e-1)" "unprognostic (6.27e-2)" "unprognostic (1.50e-1)" "unprognostic (1.64e-1)" "unprognostic (4.40e-2)" "unprognostic (1.69e-1)" OFD1 "71-7A, CXorf5, JBTS10, RP23" ENSG00000046651 "OFD1 centriole and centriolar satellite protein" O75665 X 13734743-13777955 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "pDCs: 390.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in all" 6 "plasmacytoid DC: 69.8" "Lineage enriched" "Detected in all" 6 "dendritic cells: 69.8" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031102, HPA031103, HPA031104" Approved Uncertain "Microtubules,Primary cilium,End piece" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 44: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 74 Microtubules "Primary cilium, End piece" "HPA031102: , HPA031103: , HPA031104: " "unprognostic (4.93e-2)" "unprognostic (5.82e-2)" "unprognostic (5.48e-2)" "unprognostic (1.14e-2)" "unprognostic (3.09e-2)" "unprognostic (2.17e-1)" "unprognostic (2.35e-1)" "unprognostic (2.50e-1)" "unprognostic (4.23e-2)" "unprognostic (4.98e-2)" "unprognostic (2.00e-3)" "unprognostic (2.31e-2)" "unprognostic (1.18e-1)" "unprognostic (2.58e-3)" "unprognostic (2.75e-2)" "unprognostic (1.08e-1)" "unprognostic (1.39e-1)" "unprognostic (8.69e-2)" "unprognostic (2.72e-2)" "unprognostic (6.18e-2)" "unprognostic (1.59e-1)" "unprognostic (3.12e-1)" "unprognostic (9.45e-2)" "unprognostic (1.04e-1)" "unprognostic (5.94e-2)" "unprognostic (8.52e-2)" "unprognostic (7.43e-2)" "unprognostic (8.00e-2)" "unprognostic (3.00e-1)" "unprognostic (2.45e-1)" "unprognostic (1.70e-2)" OGA "MEA5, MGEA5, NCOAT" ENSG00000198408 O-GlcNAcase O60502 10 101784443-101818465 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Host-virus interaction" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 852.6;Neutrophils: 658.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036141, HPA076501" Approved Supported Cytosol NA NA 7000 "Cluster 20: Non-specific - DNA binding" "Cluster 64: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 89: Adipocytes - Lipid metabolism" 4 Cytosol "HPA036141: , HPA076501: " "unprognostic (2.83e-2)" "unprognostic (8.69e-2)" "unprognostic (2.10e-1)" "potential prognostic unfavorable (6.58e-5)" "unprognostic (6.08e-2)" "unprognostic (1.80e-1)" "potential prognostic favorable (2.13e-4)" "unprognostic (8.08e-2)" "unprognostic (1.21e-1)" "unprognostic (3.88e-3)" "unprognostic (7.94e-3)" "unprognostic (1.97e-1)" "unprognostic (3.58e-1)" "unprognostic (1.75e-1)" "unprognostic (5.46e-2)" "unprognostic (3.34e-2)" "unprognostic (1.73e-1)" "unprognostic (1.22e-3)" "unprognostic (2.35e-1)" "unprognostic (1.22e-1)" "unprognostic (1.16e-3)" "unprognostic (8.33e-2)" "unprognostic (1.56e-3)" "unprognostic (1.68e-3)" "unprognostic (2.93e-1)" "unprognostic (1.21e-1)" "unprognostic (1.58e-2)" "unprognostic (6.30e-2)" "unprognostic (3.15e-2)" OGDH "E1k, KGD1, OGDC-E1, OGDH2" ENSG00000105953 "Oxoglutarate dehydrogenase" Q02218 7 44606572-44709066 "Citric acid cycle related proteins, Enzymes, Essential proteins, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 302.2;skeletal muscle: 340.6;tongue: 349.9" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 398.8;Neutrophils: 393.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019514, HPA020347" Supported Enhanced Mitochondria No No 91000 "Cluster 33: Non-specific - ATP binding" "Cluster 52: Non-specific - Cellular respiration" "Cluster 44: Non-specific - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 19 Mitochondria "HPA019514: , HPA020347: " "unprognostic (1.89e-1)" "unprognostic (2.15e-2)" "unprognostic (1.76e-1)" "unprognostic (9.89e-2)" "unprognostic (2.82e-2)" "unprognostic (2.99e-2)" "unprognostic (2.21e-2)" "unprognostic (6.14e-3)" "unprognostic (6.85e-2)" "unprognostic (5.28e-2)" "potential prognostic favorable (3.38e-11)" "unprognostic (1.66e-2)" "potential prognostic favorable (8.90e-4)" "unprognostic (2.07e-1)" "unprognostic (3.01e-3)" "unprognostic (7.95e-2)" "unprognostic (2.27e-1)" "unprognostic (1.57e-1)" "unprognostic (1.09e-1)" "unprognostic (1.97e-2)" "unprognostic (2.45e-1)" "unprognostic (5.84e-2)" "unprognostic (1.93e-1)" "unprognostic (1.27e-1)" "unprognostic (1.22e-1)" "unprognostic (7.14e-2)" "unprognostic (1.09e-1)" "unprognostic (1.98e-1)" "unprognostic (5.95e-2)" "unprognostic (4.41e-2)" "unprognostic (6.41e-2)" OGDHL FLJ10851 ENSG00000197444 "Oxoglutarate dehydrogenase L" Q9ULD0 10 49734641-49762379 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Glycolysis Oxidoreductase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 119.9;kidney: 113.8;liver: 74.8" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 62.5;Distal convoluted tubule cells: 130.2;Epididymal clear cells: 147.0;Hepatocytes: 60.8;Loop of henle epithelial cells: 50.9;Proximal tubule cells: 93.3;Renal collecting duct intercalated cells: 144.5;Renal connecting tubule cells: 133.9;Tuft cells: 161.4" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" 8 "Kidney Chromophobe (TCGA): 401.8;Kidney Renal Papillary Cell Carcinoma (TCGA): 149.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 21.4" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary gland ductal cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043716, HPA052497" Enhanced Approved "Nucleoli fibrillar center" NA NA "Cluster 76: Non-specific - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 15 "Nucleoli fibrillar center" "HPA043716: , HPA052497: " "unprognostic (6.62e-2)" "unprognostic (2.09e-1)" "unprognostic (9.65e-2)" "unprognostic (3.82e-2)" "unprognostic (1.39e-2)" "unprognostic (3.29e-1)" "unprognostic (2.18e-1)" "unprognostic (1.17e-1)" "potential prognostic favorable (4.31e-9)" "unprognostic (1.84e-2)" "potential prognostic favorable (2.82e-5)" "unprognostic (5.07e-3)" "potential prognostic favorable (2.35e-5)" "unprognostic (2.09e-1)" "unprognostic (3.30e-1)" "unprognostic (2.73e-1)" "unprognostic (1.74e-3)" "unprognostic (3.12e-2)" "unprognostic (5.40e-2)" "unprognostic (1.18e-3)" "unprognostic (6.53e-2)" "unprognostic (2.33e-1)" "unprognostic (9.85e-2)" "unprognostic (2.06e-1)" "unprognostic (1.72e-2)" "unprognostic (2.08e-2)" "unprognostic (2.10e-1)" "potential prognostic unfavorable (8.79e-4)" "unprognostic (9.34e-2)" OGFOD1 "FLJ10826, KIAA1612, TPA1" ENSG00000087263 "2-oxoglutarate and iron dependent oxygenase domain containing 1" Q8N543 16 56451521-56479104 "Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epicardial cells: 181.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003215, HPA003722" Approved Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 5 Nucleoplasm Cytosol "HPA003215: , HPA003722: " "unprognostic (1.66e-1)" "unprognostic (2.88e-2)" "unprognostic (2.70e-1)" "unprognostic (5.47e-3)" "unprognostic (2.97e-1)" "unprognostic (1.36e-1)" "unprognostic (5.01e-2)" "unprognostic (1.34e-1)" "unprognostic (1.69e-2)" "unprognostic (1.08e-2)" "unprognostic (1.17e-2)" "unprognostic (1.32e-1)" "unprognostic (2.98e-1)" "potential prognostic unfavorable (5.34e-5)" "unprognostic (3.32e-2)" "unprognostic (1.08e-2)" "potential prognostic unfavorable (6.92e-4)" "unprognostic (9.23e-2)" "unprognostic (6.57e-2)" "unprognostic (1.29e-1)" "unprognostic (1.57e-2)" "unprognostic (1.74e-2)" "unprognostic (1.64e-2)" "unprognostic (8.79e-2)" "unprognostic (1.09e-1)" "unprognostic (8.41e-2)" "unprognostic (5.28e-2)" "unprognostic (1.41e-1)" "unprognostic (5.66e-2)" "unprognostic (2.97e-2)" "unprognostic (1.03e-2)" OGFOD2 "FLJ13491, FLJ37501" ENSG00000111325 "2-oxoglutarate and iron dependent oxygenase domain containing 2" Q6N063 12 122974580-122980043 "Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 6.5;Bergmann glia: 5.1;Choroid plexus epithelial cells: 4.8;Ependymal cells: 11.9;Epididymal principal cells: 18.0;Microglia: 5.2;Podocytes: 5.9;Proximal tubule cells: 6.9;Tuft cells: 11.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039448, HPA040306" Approved Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 21: Testis - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 38: Non-specific - Transcription" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" Nucleoplasm "Nuclear bodies" "HPA039448: , HPA040306: " "unprognostic (8.28e-2)" "unprognostic (9.79e-2)" "unprognostic (3.59e-2)" "unprognostic (2.63e-3)" "unprognostic (2.42e-1)" "unprognostic (1.99e-1)" "unprognostic (1.88e-3)" "unprognostic (3.06e-3)" "unprognostic (8.31e-2)" "unprognostic (4.59e-3)" "unprognostic (1.73e-3)" "unprognostic (8.52e-3)" "unprognostic (1.27e-1)" "unprognostic (7.72e-3)" "unprognostic (1.49e-1)" "unprognostic (1.01e-1)" "unprognostic (3.04e-1)" "unprognostic (7.89e-2)" "unprognostic (5.32e-2)" "unprognostic (2.98e-1)" "unprognostic (1.75e-2)" "unprognostic (3.03e-2)" "unprognostic (7.35e-2)" "unprognostic (2.33e-1)" "unprognostic (5.68e-2)" "unprognostic (2.58e-2)" "unprognostic (4.27e-2)" "unprognostic (2.61e-2)" "unprognostic (2.63e-1)" "unprognostic (3.40e-2)" "unprognostic (4.35e-1)" OGFOD3 "C17orf101, FLJ22222" ENSG00000181396 "2-oxoglutarate and iron dependent oxygenase domain containing 3" Q6PK18 17 82389210-82418637 "Predicted intracellular proteins, Predicted membrane proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052099 Uncertain Approved Nucleoplasm NA NA 18000 "Cluster 29: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 6: Non-specific - Immune response" "Cluster 27: Breast cancer - Unknown function" "Cluster 67: Plasma cells - Plasma cell differentiation" 13 Nucleoplasm "HPA052099: " "unprognostic (4.05e-2)" "unprognostic (8.21e-3)" "unprognostic (1.38e-1)" "unprognostic (1.15e-3)" "unprognostic (9.45e-2)" "unprognostic (2.02e-3)" "unprognostic (1.45e-1)" "unprognostic (7.82e-2)" "unprognostic (3.87e-2)" "unprognostic (9.40e-2)" "unprognostic (3.25e-2)" "potential prognostic favorable (4.05e-4)" "unprognostic (4.20e-2)" "unprognostic (1.73e-1)" "unprognostic (1.57e-1)" "unprognostic (2.62e-2)" "unprognostic (3.63e-3)" "unprognostic (1.81e-1)" "unprognostic (2.44e-1)" "unprognostic (4.41e-2)" "unprognostic (3.85e-1)" "unprognostic (1.50e-2)" "unprognostic (2.52e-1)" "unprognostic (1.42e-1)" "unprognostic (5.98e-2)" "unprognostic (1.99e-1)" "unprognostic (1.74e-1)" "unprognostic (2.19e-1)" "unprognostic (1.26e-1)" OGFR 7-60 ENSG00000060491 "Opioid growth factor receptor" Q9NZT2 20 62804835-62814000 "Predicted intracellular proteins" "Growth regulation" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "eosinophil: 12.5;neutrophil: 3.1" "Lineage enriched" "Detected in many" 8 "granulocytes: 12.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017899 Supported Approved Nucleoplasm NA NA 32000 "Cluster 19: Eosinophils - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 53: Neurons - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 2 Nucleoplasm "HPA017899: " "unprognostic (5.65e-2)" "unprognostic (1.45e-1)" "unprognostic (8.57e-2)" "unprognostic (1.68e-1)" "unprognostic (1.25e-1)" "unprognostic (2.29e-1)" "unprognostic (9.24e-2)" "unprognostic (3.68e-2)" "unprognostic (1.30e-1)" "unprognostic (4.13e-1)" "unprognostic (1.08e-1)" "unprognostic (2.09e-1)" "unprognostic (4.02e-2)" "unprognostic (4.54e-3)" "unprognostic (1.33e-1)" "unprognostic (1.91e-1)" "unprognostic (2.49e-1)" "unprognostic (5.03e-2)" "unprognostic (3.93e-2)" "unprognostic (1.49e-1)" "unprognostic (2.99e-3)" "unprognostic (1.51e-2)" "unprognostic (5.64e-2)" "unprognostic (4.83e-2)" "unprognostic (6.21e-2)" "potential prognostic favorable (2.98e-4)" "unprognostic (3.57e-2)" "unprognostic (1.99e-2)" "unprognostic (8.37e-2)" "unprognostic (1.33e-1)" "unprognostic (1.74e-1)" OGFRL1 dJ331H24.1 ENSG00000119900 "Opioid growth factor receptor like 1" Q5TC84 6 71288811-71309059 "Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 266.0;Breast lactating cells: 227.5;cDC: 266.8;Macrophages: 276.8;Microglia: 229.7;Neutrophils: 316.0;Schwann cells: 321.6" "Cell type enhanced" "Detected in all" "astrocyte: 408.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 11.1" "Lineage enriched" "Detected in many" 4 "granulocytes: 11.1" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027122 Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 44: Non-specific - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 82: Dendritic cells - Antigen presentation" "Golgi apparatus" Nucleoplasm "HPA027122: " "unprognostic (1.44e-1)" "unprognostic (1.57e-1)" "unprognostic (4.52e-1)" "unprognostic (7.53e-2)" "unprognostic (9.27e-2)" "unprognostic (2.15e-1)" "unprognostic (2.75e-1)" "unprognostic (1.87e-1)" "unprognostic (1.45e-2)" "unprognostic (4.01e-3)" "potential prognostic favorable (3.44e-4)" "unprognostic (1.29e-1)" "unprognostic (5.42e-2)" "potential prognostic unfavorable (1.71e-4)" "unprognostic (6.69e-2)" "unprognostic (1.58e-1)" "unprognostic (6.25e-2)" "unprognostic (1.83e-2)" "unprognostic (2.90e-1)" "unprognostic (3.21e-1)" "unprognostic (1.54e-3)" "unprognostic (4.47e-2)" "unprognostic (8.63e-3)" "unprognostic (3.19e-1)" "unprognostic (2.11e-1)" "unprognostic (2.67e-2)" "unprognostic (5.01e-2)" "unprognostic (5.46e-2)" "unprognostic (8.75e-2)" "unprognostic (1.23e-1)" "unprognostic (2.49e-2)" OGG1 "HMMH, HOGG1, MUTM, OGH1" ENSG00000114026 "8-oxoguanine DNA glycosylase" O15527 3 9749944-9788219 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "Glycosidase, Hydrolase, Lyase, Multifunctional enzyme" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 74.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027514, CAB047301" Approved Enhanced Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 72: Kidney - Transmembrane transport" "Cluster 15: Non-specific - Transcription" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 6 Nucleoplasm "CAB047301: , HPA027514: " "unprognostic (7.69e-3)" "unprognostic (6.90e-2)" "unprognostic (3.82e-1)" "unprognostic (2.29e-1)" "unprognostic (7.50e-3)" "unprognostic (7.94e-2)" "unprognostic (2.48e-1)" "unprognostic (3.12e-2)" "unprognostic (8.00e-2)" "potential prognostic unfavorable (1.16e-4)" "potential prognostic favorable (5.88e-4)" "unprognostic (8.92e-2)" "potential prognostic favorable (1.15e-4)" "potential prognostic unfavorable (3.43e-8)" "unprognostic (1.12e-2)" "unprognostic (2.13e-1)" "unprognostic (3.53e-2)" "unprognostic (1.21e-1)" "unprognostic (1.77e-1)" "unprognostic (5.83e-3)" "unprognostic (1.25e-1)" "unprognostic (1.72e-1)" "unprognostic (1.63e-1)" "unprognostic (3.43e-1)" "unprognostic (3.94e-2)" "unprognostic (5.07e-3)" "unprognostic (3.39e-2)" "unprognostic (8.42e-2)" "unprognostic (3.89e-2)" "unprognostic (6.95e-2)" "unprognostic (6.75e-2)" OGN "mimecan, OIF, SLRR3A" ENSG00000106809 Osteoglycin P20774 9 92383268-92404696 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 367.4;ovary: 223.5" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 66.4;Endometrial stromal cells: 82.1;Fibro-adipogenic progenitors: 64.4;Fibroblasts: 264.1;Hepatic stellate cells: 251.7;Leydig cells: 153.2;Mesothelial cells: 463.7;Ovarian stromal cells: 195.7;Peritubular myoid cells: 201.3;Vascular smooth muscle cells: 83.7" "Cell type enriched" "Detected in all" 14 "fibroblast: 320.5" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 22.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "T-reg: 1.7" "Lineage enriched" "Detected in single" 9 "T-cells: 1.7" "Cancer enriched" "Detected in some" 6 "Rhabdoid: 22.0" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Mesothelial cells, Breast - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblasts_2, Minor Salivary Gland - Fibroblasts, Pancreas - Fibroblasts, Pituitary gland - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Spleen - Smooth muscle cells, Stomach - Fibroblasts, Testis - Peritubular cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013132 Approved Supported "Endoplasmic reticulum" "Secreted in other tissues" "Growth factor" NA NA 28000000 "Cluster 16: Non-specific - Cell proliferation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 8: Immune cells - Immune response" "Cluster 5: Rhabdoid - Unknown function" "Cluster 108: Fibroblasts - ECM organization" 3 "Endoplasmic reticulum" "HPA013132: " "unprognostic (2.44e-2)" "unprognostic (1.06e-1)" "unprognostic (1.97e-1)" "unprognostic (1.18e-3)" "unprognostic (5.86e-2)" "unprognostic (3.22e-1)" "unprognostic (1.19e-1)" "unprognostic (1.00e-2)" "unprognostic (1.37e-1)" "unprognostic (1.49e-2)" "unprognostic (5.46e-2)" "potential prognostic favorable (1.38e-5)" "unprognostic (6.92e-3)" "unprognostic (5.25e-3)" "unprognostic (7.48e-2)" "unprognostic (4.36e-1)" "unprognostic (9.88e-2)" "unprognostic (1.49e-3)" "unprognostic (2.99e-1)" "unprognostic (2.22e-1)" "unprognostic (8.89e-2)" "unprognostic (1.03e-1)" "unprognostic (5.45e-2)" "unprognostic (3.90e-2)" "unprognostic (5.04e-3)" "unprognostic (5.35e-2)" "unprognostic (3.66e-3)" "unprognostic (7.27e-2)" OGT "FLJ23071, HRNT1, MGC22921, O-GLCNAC, OGT1" ENSG00000147162 "O-linked N-acetylglucosamine (GlcNAc) transferase" O15294 X 71533087-71575892 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Biological rhythms, Host-virus interaction, Ubl conjugation pathway" "Chromatin regulator, Glycosyltransferase, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030751, HPA030752, HPA030753, HPA030754, CAB034099" Approved Supported "Nucleoplasm,Plasma membrane" Yes No 3600 "Cluster 14: Non-specific - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 53: Neurons - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 9: T-cells - Adaptive immunity: Regulation" 124 Nucleoplasm "Plasma membrane" "CAB034099: , HPA030751: , HPA030752: , HPA030753: , HPA030754: " "potential prognostic favorable (4.12e-4)" "unprognostic (9.34e-3)" "unprognostic (1.25e-1)" "unprognostic (9.57e-2)" "unprognostic (6.48e-2)" "unprognostic (2.73e-2)" "unprognostic (1.47e-2)" "unprognostic (4.18e-3)" "potential prognostic favorable (1.00e-3)" "unprognostic (7.74e-3)" "unprognostic (1.36e-3)" "unprognostic (1.76e-1)" "unprognostic (3.16e-1)" "potential prognostic unfavorable (1.02e-4)" "unprognostic (3.54e-1)" "unprognostic (1.49e-3)" "unprognostic (1.45e-1)" "unprognostic (2.48e-2)" "unprognostic (3.01e-2)" "unprognostic (8.39e-2)" "unprognostic (9.67e-2)" "unprognostic (1.37e-1)" "unprognostic (1.85e-2)" "unprognostic (1.17e-1)" "unprognostic (4.94e-2)" "unprognostic (6.59e-3)" "unprognostic (4.64e-2)" "unprognostic (4.00e-2)" "unprognostic (2.21e-1)" "unprognostic (2.80e-2)" "unprognostic (1.29e-3)" OIP5 "CT86, hMIS18beta, MIS18B" ENSG00000104147 "Opa interacting protein 5" O43482 15 41309273-41332591 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 9.7;skeletal muscle: 9.6;testis: 19.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 58.8;Differentiating spermatogonia: 92.3;Early primary spermatocytes: 108.1;Epicardial cells: 47.8;Late primary spermatocytes: 132.7;Myonuclei: 131.4;Oocytes: 101.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA052271, HPA059602" Enhanced Supported "Nuclear speckles,Vesicles" NA Yes "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 39: Testis - Nuclear processes" "Cluster 25: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 134 "Nuclear speckles" Vesicles "HPA052271: , HPA059602: " "unprognostic (5.99e-3)" "unprognostic (1.64e-2)" "unprognostic (2.63e-1)" "unprognostic (1.27e-1)" "unprognostic (6.60e-2)" "unprognostic (1.96e-1)" "unprognostic (5.47e-2)" "unprognostic (5.81e-3)" "unprognostic (1.50e-1)" "potential prognostic unfavorable (5.40e-4)" "validated prognostic unfavorable (1.19e-4)" "validated prognostic unfavorable (3.01e-4)" "potential prognostic unfavorable (2.85e-6)" "validated prognostic unfavorable (3.46e-4)" "validated prognostic unfavorable (2.38e-8)" "potential prognostic unfavorable (1.94e-5)" "unprognostic (2.38e-3)" "unprognostic (5.36e-3)" "unprognostic (4.68e-2)" "unprognostic (3.98e-2)" "unprognostic (1.23e-1)" "potential prognostic unfavorable (1.48e-4)" "unprognostic (2.87e-2)" "unprognostic (8.77e-3)" "unprognostic (4.19e-2)" "unprognostic (2.84e-1)" "unprognostic (2.42e-2)" "unprognostic (5.22e-2)" "unprognostic (3.58e-1)" "unprognostic (4.17e-2)" OIT3 "FLJ39116, LZP" ENSG00000138315 "Oncoprotein induced transcript 3" Q8WWZ8 10 72893584-72933036 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "liver: 103.6" "Cell type enhanced" "Detected in many" "Epididymal clear cells: 14.3;Hepatic stellate cells: 6.5;Kupffer cells: 14.3;Lymphatic endothelial cells: 5.6;Neutrophil progenitors: 6.3;Vascular endothelial cells: 23.9" "Cell type enhanced" "Detected in many" "upper rhombic lip: 6.3" "Cancer enhanced" "Detected in some" "Liver Hepatocellular Carcinoma (TCGA): 5.9" "Region enhanced" "Detected in some" "cerebellum: 2.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "liver cancer: 1.3" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" "No annotated function" NA NA 47000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 35: Non-specific - DNA binding" "Cluster 1: Neuronal - Visual perception" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 9 "unprognostic (3.28e-2)" "unprognostic (5.33e-2)" "validated prognostic favorable (6.64e-8)" "validated prognostic favorable (1.41e-6)" "unprognostic (7.09e-2)" "unprognostic (3.19e-2)" "unprognostic (4.31e-2)" "unprognostic (9.52e-3)" "unprognostic (2.48e-1)" "unprognostic (8.94e-3)" OLA1 "GTPBP9, PTD004" ENSG00000138430 "Obg like ATPase 1" Q9NTK5 2 174072447-174248599 "Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035790, HPA041443" Approved Enhanced Cytosol NA NA 1700000 "Cluster 13: Non-specific - Mitochondria" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 17: Non-specific - RNA processing" 12 Cytosol "HPA035790: , HPA041443: " "unprognostic (3.02e-2)" "unprognostic (1.83e-1)" "unprognostic (4.83e-2)" "unprognostic (1.23e-1)" "unprognostic (5.89e-2)" "unprognostic (2.81e-1)" "unprognostic (2.50e-1)" "unprognostic (1.44e-1)" "unprognostic (1.06e-2)" "unprognostic (1.17e-2)" "potential prognostic favorable (7.43e-5)" "unprognostic (5.04e-2)" "unprognostic (6.41e-3)" "validated prognostic unfavorable (1.35e-9)" "validated prognostic unfavorable (5.20e-6)" "potential prognostic unfavorable (3.18e-4)" "unprognostic (3.96e-3)" "unprognostic (4.73e-2)" "unprognostic (2.16e-2)" "unprognostic (2.43e-2)" "unprognostic (2.69e-1)" "unprognostic (9.89e-3)" "unprognostic (2.49e-1)" "unprognostic (2.24e-1)" "unprognostic (3.71e-2)" "unprognostic (3.42e-2)" "unprognostic (1.37e-1)" "unprognostic (1.73e-1)" "unprognostic (2.28e-1)" "unprognostic (1.50e-2)" "unprognostic (1.02e-1)" OLAH "FLJ11106, SAST, THEDC1" ENSG00000152463 "Oleoyl-ACP hydrolase" Q9NV23 10 15032227-15073853 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 9.0;testis: 25.2" "Cell type enhanced" "Detected in some" "Breast lactating cells: 1784.9;Early spermatids: 694.0;Late primary spermatocytes: 278.3;Neutrophils: 635.1" "Cell type enhanced" "Detected in some" "Bergmann glia: 5.9;fibroblast: 6.9;pericyte: 8.9;vascular associated smooth muscle cell: 7.5" "Cancer enriched" "Detected in some" 4 "Testicular Germ Cell Tumor (TCGA): 8.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 2.6" "Lineage enriched" "Detected in single" 5 "granulocytes: 2.6" "Low cancer specificity" "Detected in some" "Adipose visceral - Neutrophils, Adrenal gland - Fibroblasts, Minor Salivary Gland - Minor salivary glandular cells, Skin - Sebaceous gland cells, Spleen - Neutrophils_2, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA037947, HPA037948" Enhanced NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 47: Testis - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 4: Breast lactating luminal cells - Lactation" "HPA037947: , HPA037948: " "unprognostic (3.96e-1)" "unprognostic (3.67e-3)" "unprognostic (2.23e-1)" "unprognostic (1.81e-1)" "unprognostic (1.33e-1)" OLFM1 "AMY, NOE1, NOELIN, OlfA" ENSG00000130558 "Olfactomedin 1" Q99784 9 135075422-135121180 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "brain: 906.9" "Cell type enhanced" "Detected in many" "Bergmann glia: 69.3;Brain excitatory neurons: 159.6;Brain inhibitory neurons: 59.9;Endometrial secretory cells: 56.7;Epididymal principal cells: 53.4;Lactotrophs: 64.0;Lymphatic endothelial cells: 46.8;Oligodendrocyte progenitor cells: 53.5;Other brain neurons: 68.8;Schwann cells: 78.3;Somatotrophs: 62.9;Vascular endothelial cells: 100.8" "Cell type enhanced" "Detected in all" "hippocampal dentate gyrus: 388.1" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 110.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.8;intermediate monocyte: 2.8;myeloid DC: 2.6" "Group enriched" "Detected in many" 27 "dendritic cells: 2.6;monocytes: 2.8" "Cancer enhanced" "Detected in many" "Bone cancer: 111.1;Neuroblastoma: 78.3" "Lung - Fibroblasts_2, Pituitary gland - Lactotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057444 Approved Nucleoplasm,Nucleoli,Cytosol "Secreted in brain" "Developmental protein" NA NA 120000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 1 Nucleoli "Nucleoplasm, Cytosol" "HPA057444: " "unprognostic (8.23e-2)" "unprognostic (2.43e-1)" "unprognostic (7.64e-3)" "unprognostic (9.27e-3)" "unprognostic (4.79e-1)" "unprognostic (9.40e-2)" "unprognostic (1.03e-3)" "unprognostic (1.61e-1)" "unprognostic (2.08e-1)" "unprognostic (7.75e-3)" "unprognostic (3.81e-1)" "unprognostic (1.19e-2)" "unprognostic (3.08e-1)" "unprognostic (3.17e-1)" "potential prognostic favorable (1.16e-4)" "unprognostic (1.11e-3)" "unprognostic (8.47e-2)" "unprognostic (5.46e-2)" "unprognostic (4.35e-2)" "unprognostic (2.47e-2)" "unprognostic (8.02e-3)" "unprognostic (2.05e-3)" "unprognostic (3.85e-2)" "unprognostic (2.43e-1)" "unprognostic (2.10e-1)" "unprognostic (5.28e-2)" "unprognostic (2.10e-1)" "unprognostic (1.85e-1)" "unprognostic (9.67e-2)" "unprognostic (6.99e-2)" "unprognostic (1.47e-1)" OLFM2 "NOE2, OlfC" ENSG00000105088 "Olfactomedin 2" O95897 19 9853718-9936515 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 168.1;skin 1: 85.3" "Cell type enhanced" "Detected in many" "Astrocytes: 199.8;Basal keratinocytes: 140.0;Bergmann glia: 137.0;Lactotrophs: 77.8;Late spermatids: 95.1;Müller glia: 125.6;Oligodendrocyte progenitor cells: 225.2;Suprabasal keratinocytes: 122.0" "Cell type enhanced" "Detected in all" "oligodendrocyte precursor cell: 247.0" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 207.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 49.8" "Group enriched" "Detected in many" 26 "granulocytes: 49.8;T-cells: 17.0" "Cancer enhanced" "Detected in many" "Bone cancer: 39.5" "Kidney - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Keratinocyte (other), Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049961, HPA057771" Uncertain Supported Nucleoplasm "Secreted in other tissues" "No annotated function" NA NA 3200000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 78: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 26: Keratinocytes - Keratinization" 34 Nucleoplasm "HPA049961: , HPA057771: " "unprognostic (2.44e-3)" "unprognostic (3.05e-2)" "unprognostic (1.44e-2)" "unprognostic (6.74e-3)" "potential prognostic unfavorable (2.29e-5)" "unprognostic (1.49e-1)" "unprognostic (2.48e-1)" "unprognostic (6.40e-3)" "unprognostic (5.47e-2)" "unprognostic (3.64e-2)" "unprognostic (1.32e-2)" "unprognostic (9.79e-3)" "unprognostic (4.66e-3)" "unprognostic (2.13e-1)" "potential prognostic favorable (5.94e-5)" "unprognostic (1.25e-1)" "unprognostic (1.69e-1)" "unprognostic (1.91e-2)" "unprognostic (9.27e-3)" "unprognostic (2.79e-2)" "potential prognostic unfavorable (8.26e-4)" "unprognostic (1.73e-2)" "unprognostic (8.23e-2)" "unprognostic (3.55e-1)" "unprognostic (8.09e-2)" "unprognostic (3.12e-2)" "unprognostic (1.15e-1)" "unprognostic (9.79e-2)" "unprognostic (2.39e-2)" "unprognostic (4.68e-3)" "unprognostic (1.29e-2)" OLFM3 NOE3 ENSG00000118733 "Olfactomedin 3" Q96PB7 1 101802560-101996926 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 17.1;retina: 6.8" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 503.0;Brain inhibitory neurons: 349.0;Lactotrophs: 136.4;Megakaryocyte progenitors: 68.8;Other brain neurons: 195.9;Respiratory ionocytes: 121.9;Retinal amacrine cells: 385.0;Retinal bipolar cells: 121.6;Retinal ganglion cells: 96.6" "Cell type enhanced" "Detected in all" "deep-layer near-projecting: 1544.0" "Cancer enhanced" "Detected in single" "Ovary Serous Cystadenocarcinoma (TCGA): 1.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Rhabdoid: 36.2" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pituitary gland - Lactotropes" "Region enhanced" "Detected in all" "cerebellum: 177.3" "Low region specificity" "Detected in all" HPA050297 Uncertain Vesicles "Secreted in brain" "No annotated function" NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 14: Neurons - Synaptic function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 3 Vesicles "HPA050297: " "unprognostic (1.50e-1)" "unprognostic (1.96e-1)" OLFM4 "GC1, GW112, OlfD" ENSG00000102837 "Olfactomedin 4" Q6UX06 13 53028813-53052057 "Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1220.0;pancreas: 666.4" "Cell type enhanced" "Detected in many" "Enteric stem cells: 3771.2;Enteric transient amplifying cells: 1899.8;Gastric progenitor cells: 1996.8;Neutrophil progenitors: 3094.3;Pancreatic acinar cells: 888.4;Paneth cells: 6605.5;Prostatic club cells: 5605.8;Prostatic hillock cells: 1459.4" "Low cell type specificity" "Detected in some" "Group enriched" "Detected in many" 12 "Colon Adenocarcinoma (TCGA): 1060.5;Pancreatic Adenocarcinoma (TCGA): 847.1;Rectum Adenocarcinoma (TCGA): 758.1;Stomach Adenocarcinoma (TCGA): 974.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "colorectal cancer: 123.7;Gastric cancer: 42.1" "Colon - Colon enterocytes, Lung - Neutrophils_1, Prostate - Urothelial cells, Spleen - Neutrophils_1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA077718 Enhanced Supported "Nucleoplasm,Plasma membrane,Cytokinetic bridge,Cytosol" "Secreted to digestive system" "Cell adhesion" Yes NA 840000 "Cluster 77: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 27 "Nucleoplasm, Plasma membrane" "Cytokinetic bridge, Cytosol" "HPA077718: " "unprognostic (2.03e-1)" "unprognostic (8.08e-3)" "unprognostic (3.62e-3)" "unprognostic (8.93e-2)" "unprognostic (8.87e-2)" "unprognostic (8.59e-3)" "unprognostic (5.80e-2)" "unprognostic (1.47e-1)" "unprognostic (1.67e-3)" "unprognostic (3.29e-2)" "unprognostic (1.67e-1)" "unprognostic (8.54e-2)" "unprognostic (3.22e-1)" "unprognostic (6.21e-3)" "unprognostic (1.55e-1)" "unprognostic (6.87e-2)" "unprognostic (5.05e-2)" "unprognostic (1.80e-3)" "unprognostic (6.71e-2)" "unprognostic (1.37e-2)" "unprognostic (1.64e-3)" "unprognostic (4.90e-2)" "unprognostic (2.33e-1)" "unprognostic (5.08e-2)" OLFML1 UNQ564 ENSG00000183801 "Olfactomedin like 1" Q6UWY5 11 7485388-7511377 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 63.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 28.9;Decidual stromal cells: 19.3;Epicardial cells: 15.9;Fibro-adipogenic progenitors: 25.3;Fibroblasts: 46.6;Hepatic stellate cells: 51.6;Leydig cells: 35.5;Lymphatic endothelial cells: 15.6;Mesothelial cells: 13.6;Ovarian stromal cells: 27.1;Pericytes: 21.7;Peritubular myoid cells: 37.4;Vascular smooth muscle cells: 15.2" "Group enriched" "Detected in many" 4 "choroid plexus epithelial cell: 8.6;fibroblast: 15.8;pericyte: 28.8;vascular associated smooth muscle cell: 12.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 18.4" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Fibroblasts, Breast - Fibroblasts, Colon - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Minor Salivary Gland - Fibroblasts, Pancreas - Fibroblasts, Pituitary gland - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Testis - Peritubular cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Region enriched" "Detected in single" 6 "spinal cord: 3.6" HPA058824 Approved "Secreted - unknown location" "No annotated function" NA NA 250000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 75: Ovary - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 72: Neuronal - Signal transduction" "Cluster 108: Fibroblasts - ECM organization" "HPA058824: " "unprognostic (1.65e-2)" "unprognostic (1.17e-1)" "unprognostic (2.51e-1)" "unprognostic (5.52e-2)" "unprognostic (1.01e-1)" "unprognostic (1.67e-1)" "unprognostic (3.48e-1)" "unprognostic (1.18e-2)" "unprognostic (2.44e-3)" "unprognostic (6.51e-2)" "unprognostic (1.90e-1)" "unprognostic (2.49e-2)" "potential prognostic unfavorable (2.76e-5)" "unprognostic (1.80e-1)" "unprognostic (1.89e-3)" "unprognostic (8.91e-3)" "unprognostic (7.60e-2)" "unprognostic (5.12e-2)" "unprognostic (1.97e-1)" "unprognostic (2.14e-3)" "unprognostic (7.46e-3)" "unprognostic (2.94e-1)" "unprognostic (5.38e-2)" "unprognostic (6.73e-2)" "unprognostic (1.51e-1)" "unprognostic (2.33e-2)" "unprognostic (5.07e-2)" "unprognostic (1.39e-3)" "unprognostic (1.77e-2)" "unprognostic (4.74e-2)" "unprognostic (2.51e-2)" OLFML2A FLJ00237 ENSG00000185585 "Olfactomedin like 2A" Q68BL7 9 124777133-124814885 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 28.4;Epididymal efferent duct absorptive cells: 22.3;Fibroblasts: 25.4;Lymphatic endothelial cells: 52.9;Myosatellite cells: 22.8;Pericytes: 25.3;Schwann cells: 53.6;Smooth muscle cells: 31.0;Thymic myoid cells: 54.4;Vascular endothelial cells: 27.9;Vascular smooth muscle cells: 61.7" "Group enriched" "Detected in some" 8 "endothelial cell: 26.2;fibroblast: 69.4;pericyte: 65.5;vascular associated smooth muscle cell: 89.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Liver - Hepatic stellate cells, Minor Salivary Gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021180, HPA022254" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" "Secreted - unknown location" "No annotated function" NA NA 300000 "Cluster 5: Spleen - Immune response" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 69: Skin cancer - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" "Nucleoplasm, Vesicles" "Golgi apparatus" "HPA021180: , HPA022254: " "unprognostic (1.78e-1)" "unprognostic (2.33e-1)" "unprognostic (3.20e-1)" "unprognostic (1.20e-1)" "unprognostic (3.51e-1)" "unprognostic (2.32e-1)" "unprognostic (3.62e-2)" "potential prognostic unfavorable (8.22e-4)" "unprognostic (9.30e-2)" "unprognostic (1.34e-2)" "validated prognostic favorable (7.79e-7)" "validated prognostic favorable (4.31e-4)" "unprognostic (1.69e-3)" "unprognostic (1.21e-1)" "unprognostic (2.37e-1)" "unprognostic (2.47e-1)" "potential prognostic unfavorable (7.91e-4)" "unprognostic (2.65e-1)" "unprognostic (4.25e-2)" "unprognostic (7.36e-2)" "unprognostic (3.66e-2)" "unprognostic (6.05e-2)" "unprognostic (8.61e-2)" "unprognostic (1.91e-1)" "unprognostic (1.75e-1)" "unprognostic (6.62e-3)" "unprognostic (1.88e-3)" "unprognostic (2.87e-3)" "unprognostic (4.94e-2)" "unprognostic (3.19e-1)" "unprognostic (1.03e-1)" OLFML2B DKFZP586L151 ENSG00000162745 "Olfactomedin like 2B" Q68BL8 1 161983192-162023869 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 52.2;Early spermatids: 67.3;Endometrial stromal cells: 28.7;Fibro-adipogenic progenitors: 39.7;Fibroblasts: 31.6;Hofbauer cells: 75.8;Kupffer cells: 49.2;Late primary spermatocytes: 143.4;Leydig cells: 29.5;Macrophages: 49.8;Myosatellite cells: 175.4;Pericytes: 47.8;Peritubular myoid cells: 41.8;Vascular smooth muscle cells: 32.2" "Group enriched" "Detected in many" 6 "central nervous system macrophage: 30.4;committed oligodendrocyte precursor: 13.2;deep-layer corticothalamic and 6b: 26.7;deep-layer intratelencephalic: 10.1;fibroblast: 29.3;hippocampal CA4: 23.4;midbrain-derived inhibitory: 29.0;vascular associated smooth muscle cell: 24.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "intermediate monocyte: 6.7;non-classical monocyte: 5.5" "Lineage enriched" "Detected in single" 11 "monocytes: 6.7" "Cancer enhanced" "Detected in many" "Rhabdoid: 80.6;Sarcoma: 41.3" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblasts_1, Spleen - Macrophages, Thyroid gland - Fibroblasts" "Group enriched" "Detected in all" 4 "hippocampal formation: 41.0;white matter: 11.9" "Low region specificity" "Detected in all" "HPA054136, HPA062739" Approved Approved Cytosol "Secreted - unknown location" "No annotated function" NA NA 42000 "Cluster 40: Monocytes - Innate immune response" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 23: Choroid plexus - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" 1 Cytosol "HPA054136: , HPA062739: " "unprognostic (1.41e-1)" "unprognostic (2.21e-2)" "unprognostic (4.84e-2)" "unprognostic (3.10e-2)" "unprognostic (1.91e-2)" "unprognostic (6.84e-2)" "unprognostic (2.91e-2)" "unprognostic (1.06e-1)" "unprognostic (8.66e-3)" "unprognostic (2.96e-2)" "unprognostic (2.30e-2)" "unprognostic (3.59e-1)" "potential prognostic unfavorable (4.41e-6)" "potential prognostic unfavorable (1.55e-4)" "unprognostic (3.16e-3)" "unprognostic (9.13e-2)" "unprognostic (2.84e-2)" "unprognostic (6.69e-2)" "unprognostic (9.74e-2)" "unprognostic (1.24e-3)" "unprognostic (7.44e-2)" "unprognostic (1.33e-1)" "unprognostic (1.26e-1)" "unprognostic (3.42e-1)" "unprognostic (2.92e-1)" "unprognostic (3.55e-2)" "unprognostic (1.28e-1)" "potential prognostic unfavorable (2.33e-4)" "unprognostic (2.30e-2)" "unprognostic (8.61e-3)" "unprognostic (3.47e-2)" OLFML3 "HNOEL-iso, OLF44" ENSG00000116774 "Olfactomedin like 3" Q9NRN5 1 113979391-114035572 "Predicted intracellular proteins, Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 238.5" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 466.7;Endometrial stromal cells: 102.2;Fibroblasts: 261.8;Hepatic stellate cells: 664.8;Microglia: 67.5;Ovarian stromal cells: 171.2;Smooth muscle cells: 69.5" "Group enriched" "Detected in some" 7 "central nervous system macrophage: 65.0;fibroblast: 125.7;pericyte: 32.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "myeloid DC: 2.1" "Lineage enriched" "Detected in single" 12 "dendritic cells: 2.1" "Cancer enhanced" "Detected in many" "Bone cancer: 137.5;testis cancer: 132.0" "Adrenal gland - Fibroblasts, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblasts_1, Pituitary gland - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblasts_2, Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027991 Supported Vesicles "Secreted to extracellular matrix" "Developmental protein" NA NA 3100000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" Vesicles "HPA027991: " "unprognostic (6.27e-3)" "unprognostic (8.04e-2)" "unprognostic (2.35e-1)" "unprognostic (5.04e-2)" "unprognostic (5.78e-2)" "unprognostic (2.41e-1)" "unprognostic (3.16e-1)" "unprognostic (4.21e-2)" "unprognostic (1.07e-1)" "unprognostic (2.09e-1)" "unprognostic (3.18e-2)" "unprognostic (9.12e-2)" "unprognostic (1.13e-1)" "unprognostic (2.97e-1)" "unprognostic (3.93e-2)" "unprognostic (8.59e-2)" "unprognostic (9.06e-3)" "unprognostic (5.84e-2)" "unprognostic (4.41e-2)" "unprognostic (8.68e-3)" "unprognostic (9.95e-3)" "unprognostic (9.03e-2)" "unprognostic (2.20e-2)" "unprognostic (2.29e-1)" "unprognostic (2.07e-1)" "unprognostic (4.94e-2)" "unprognostic (1.02e-1)" "unprognostic (5.55e-3)" "unprognostic (1.48e-1)" "unprognostic (9.37e-2)" "unprognostic (3.97e-1)" OLIG1 "BHLHB6, bHLHe21" ENSG00000184221 "Oligodendrocyte transcription factor 1" Q8TAK6 21 33070141-33072413 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 48 "brain: 228.3" "Group enriched" "Detected in some" 24 "Oligodendrocyte progenitor cells: 701.1;Oligodendrocytes: 247.7" "Group enriched" "Detected in many" 31 "committed oligodendrocyte precursor: 272.9;oligodendrocyte: 231.0;oligodendrocyte precursor cell: 746.8" "Cancer enriched" "Detected in some" 10 "Glioblastoma Multiforme (TCGA): 214.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "basophil: 12.1;eosinophil: 37.6" "Lineage enriched" "Detected in many" 15 "granulocytes: 37.6" "Cancer enhanced" "Detected in some" "Leukemia: 6.7;Myeloma: 3.7" "Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 15 "unprognostic (1.73e-2)" "potential prognostic favorable (8.96e-4)" "unprognostic (5.97e-3)" "unprognostic (6.22e-3)" "unprognostic (4.13e-2)" "unprognostic (3.51e-1)" OLIG2 "BHLHB1, bHLHe19, OLIGO2, PRKCBP2, RACK17" ENSG00000205927 "Oligodendrocyte transcription factor 2" Q13516 21 33025935-33029196 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "brain: 57.7" "Group enriched" "Detected in some" 27 "Oligodendrocyte progenitor cells: 248.2;Oligodendrocytes: 70.2" "Cell type enhanced" "Detected in some" "committed oligodendrocyte precursor: 125.2;oligodendrocyte precursor cell: 276.8" "Cancer enriched" "Detected in some" 53 "Glioblastoma Multiforme (TCGA): 115.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "eosinophil: 19.0" "Lineage enriched" "Detected in single" 190 "granulocytes: 19.0" "Cancer enhanced" "Detected in some" "Leukemia: 2.5;Sarcoma: 3.5;skin cancer: 5.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003254, CAB019381" Enhanced Uncertain "Nucleoplasm,Plasma membrane" NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 49: HMC-1 - Innate immune response" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 2 Nucleoplasm "Plasma membrane" "CAB019381: , HPA003254: " "unprognostic (1.05e-2)" "potential prognostic favorable (6.99e-4)" "unprognostic (5.19e-2)" OLIG3 "Bhlhb7, bHLHe20" ENSG00000177468 "Oligodendrocyte transcription factor 3" Q7RTU3 6 137492199-137494394 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Sebaceous gland cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018303, CAB024865" Uncertain NA NA "Cluster 65: Non-specific - Unknown function" "Cluster 51: Secretory epithelial cells - Mixed function" 25 "CAB024865: , HPA018303: " OLR1 "CLEC8A, LOX-1, SCARE1" ENSG00000173391 "Oxidized low density lipoprotein receptor 1" P78380 12 10158301-10172138 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Immunity, Inflammatory response" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 94.3;placenta: 107.4" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 590.9;Macrophages: 318.3;Microglia: 441.5;Migrating cytotrophoblasts: 288.4;monocytes: 615.5;Neutrophil progenitors: 192.1;Neutrophils: 172.8;Syncytiotrophoblasts: 572.1" "Cell type enriched" "Detected in many" 35 "central nervous system macrophage: 466.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.8" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "cervical cancer: 116.7;head and neck cancer: 80.2" "Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA050798 Approved "Nucleoplasm,Vesicles,Plasma membrane" "Intracellular and membrane" Receptor NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 4 "Nucleoplasm, Plasma membrane" Vesicles "HPA050798: " "unprognostic (1.09e-1)" "unprognostic (2.12e-1)" "unprognostic (6.10e-2)" "unprognostic (2.56e-2)" "unprognostic (1.32e-2)" "unprognostic (1.80e-1)" "unprognostic (8.42e-2)" "unprognostic (8.80e-2)" "potential prognostic unfavorable (3.53e-4)" "unprognostic (2.82e-1)" "unprognostic (2.10e-1)" "unprognostic (1.38e-1)" "unprognostic (3.69e-2)" "unprognostic (4.98e-2)" "unprognostic (1.81e-1)" "unprognostic (8.86e-3)" "unprognostic (8.27e-2)" "unprognostic (1.26e-2)" "unprognostic (1.02e-1)" "unprognostic (4.49e-2)" "unprognostic (2.66e-1)" "unprognostic (1.38e-2)" "unprognostic (1.91e-2)" "unprognostic (2.62e-1)" "unprognostic (3.95e-3)" "unprognostic (2.16e-3)" "unprognostic (3.60e-2)" "unprognostic (2.14e-2)" "unprognostic (1.23e-1)" "unprognostic (1.55e-2)" "unprognostic (1.16e-2)" OMA1 "FLJ33782, MPRP-1, YKR087C, ZMPOMA1" ENSG00000162600 "OMA1 zinc metallopeptidase" Q96E52 1 58415384-58546802 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 13.7;Parietal cells: 15.9;Tuft cells: 11.5" "Cell type enhanced" "Detected in many" "oligodendrocyte: 8.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055120 Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 97: Non-specific - Cellular respiration" 9 "Nucleoplasm, Mitochondria" "HPA055120: " "unprognostic (9.10e-2)" "unprognostic (9.46e-2)" "unprognostic (2.00e-1)" "unprognostic (2.74e-1)" "unprognostic (7.62e-3)" "unprognostic (8.52e-2)" "unprognostic (3.93e-1)" "unprognostic (7.34e-3)" "unprognostic (9.20e-2)" "unprognostic (2.01e-2)" "unprognostic (1.46e-2)" "unprognostic (2.44e-2)" "unprognostic (6.90e-2)" "potential prognostic unfavorable (7.51e-5)" "unprognostic (6.79e-2)" "unprognostic (9.17e-2)" "unprognostic (3.32e-1)" "unprognostic (1.05e-1)" "unprognostic (2.94e-1)" "unprognostic (5.60e-2)" "unprognostic (9.95e-2)" "unprognostic (9.11e-3)" "unprognostic (5.03e-2)" "unprognostic (7.41e-2)" "potential prognostic favorable (4.00e-4)" "unprognostic (8.86e-2)" "unprognostic (6.49e-3)" "unprognostic (5.50e-2)" "unprognostic (3.64e-1)" "unprognostic (1.35e-1)" "unprognostic (1.37e-1)" OMD "osteoadherin, SLRR2C" ENSG00000127083 Osteomodulin Q99983 9 92412380-92424471 "Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 63.3" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 121.3;Fibro-adipogenic progenitors: 58.3;Fibroblasts: 136.1;Leydig cells: 140.9;Mesothelial cells: 72.0;Myonuclei: 60.0;Ovarian stromal cells: 79.9;Peritubular myoid cells: 173.2;Retinal ganglion cells: 65.7;Rod photoreceptor cells: 50.6" "Group enriched" "Detected in all" 6 "endothelial cell: 46.0;fibroblast: 134.5" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 7.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Mast cells, Adipose visceral - Mesothelial cells, Adrenal gland - Fibroblasts, Breast - Fibroblasts, Colon - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Minor Salivary Gland - Fibroblasts, Pancreas - Fibroblasts, Pituitary gland - Fibroblasts, Skin - Fibroblasts_2, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA069948 Approved "Nucleoli fibrillar center,Endoplasmic reticulum" "Secreted in other tissues" "Cell adhesion" NA NA 22000000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" "Endoplasmic reticulum" "Nucleoli fibrillar center" "HPA069948: " "unprognostic (2.70e-3)" "unprognostic (1.39e-1)" "unprognostic (1.13e-1)" "unprognostic (3.46e-1)" "potential prognostic unfavorable (2.02e-4)" "unprognostic (4.46e-3)" "unprognostic (1.14e-1)" "unprognostic (3.44e-1)" "unprognostic (1.77e-1)" "unprognostic (1.28e-1)" "unprognostic (1.18e-1)" "potential prognostic unfavorable (7.95e-4)" "unprognostic (2.12e-1)" "unprognostic (2.16e-2)" "unprognostic (1.78e-1)" "potential prognostic favorable (5.39e-5)" "unprognostic (4.01e-3)" "unprognostic (5.60e-2)" "unprognostic (1.11e-3)" OMG OMGP ENSG00000126861 "Oligodendrocyte myelin glycoprotein" P23515 17 31272013-31297539 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 80.4" "Cell type enhanced" "Detected in many" "Bergmann glia: 117.8;Cardiomyocytes: 204.4;Endometrial ciliated cells: 503.7;Epicardial cells: 234.2;Fallopian tube ciliated cells: 123.6;Oligodendrocyte progenitor cells: 146.9;Oligodendrocytes: 191.4;Respiratory ciliated cells: 367.7" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in some" 14 "Glioblastoma Multiforme (TCGA): 31.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008206, HPA012693" Enhanced "Intracellular and membrane" "Cell adhesion" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 34: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 107: Ciliated cells - Cilia assembly & function" 1 "HPA008206: , HPA012693: " "unprognostic (1.51e-1)" "unprognostic (9.29e-2)" "unprognostic (3.47e-3)" "unprognostic (4.18e-1)" "unprognostic (2.72e-1)" OMP ENSG00000254550 "Olfactory marker protein" P47874 11 77102840-77103331 "Predicted intracellular proteins" "Olfaction, Sensory transduction" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 2.5;liver: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in some" 62 "olfactory bulb: 96.7" NA NA "Cluster 77: Intestine - Digestion" "Cluster 49: Hindbrain - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" 2 "unprognostic (1.39e-1)" "unprognostic (5.94e-2)" "unprognostic (1.25e-2)" "unprognostic (8.52e-2)" "unprognostic (2.23e-2)" "unprognostic (6.51e-2)" "unprognostic (4.35e-3)" ONECUT1 "HNF-6, HNF6, HNF6A" ENSG00000169856 "One cut homeobox 1" Q9UBC0 15 52755053-52791078 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "gallbladder: 5.4;liver: 12.2;pancreas: 14.0;retina: 3.8" "Cell type enhanced" "Detected in some" "Cholangiocytes: 278.1;Hepatocytes: 116.3;Pancreatic acinar cells: 119.3;Pancreatic duct cells: 173.7;Retinal ganglion cells: 100.4;Retinal horizontal cells: 1041.8" "Cell type enhanced" "Detected in some" "cerebellar inhibitory: 16.5;oligodendrocyte precursor cell: 34.7" "Group enriched" "Detected in some" 6 "Liver Hepatocellular Carcinoma (TCGA): 5.5;Pancreatic Adenocarcinoma (TCGA): 1.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 4.9" "Region enhanced" "Detected in single" "hypothalamus: 1.0" "Low region specificity" "Detected in some" HPA003457 Enhanced Supported Nucleoplasm NA NA "Cluster 70: Non-specific - Protein processing" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 18: Liver cancer - Metabolism" "Cluster 109: Neurons - Neuronal signaling" 3 Nucleoplasm "HPA003457: " "unprognostic (6.48e-2)" "unprognostic (1.82e-1)" "unprognostic (2.43e-2)" "unprognostic (9.80e-2)" "unprognostic (1.27e-1)" "unprognostic (1.80e-2)" ONECUT2 OC-2 ENSG00000119547 "One cut homeobox 2" O95948 18 57435374-57491298 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "gallbladder: 9.5;intestine: 9.5;liver: 7.9;retina: 5.0" "Cell type enhanced" "Detected in some" "Brain inhibitory neurons: 102.3;Cholangiocytes: 165.4;Gastric progenitor cells: 162.8;Hepatocytes: 66.1;Pancreatic duct cells: 156.9;Retinal horizontal cells: 581.0" "Group enriched" "Detected in many" 4 "mammillary body: 263.4;medium spiny neuron: 258.1" "Group enriched" "Detected in some" 5 "Liver Hepatocellular Carcinoma (TCGA): 5.0;Pancreatic Adenocarcinoma (TCGA): 5.8;Stomach Adenocarcinoma (TCGA): 7.3" "Region enhanced" "Detected in many" "basal ganglia: 20.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Stomach - Gastric enteroendocrine cells, Testis - Spermatocytes" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 5 "basal ganglia: 13.0;cerebellum: 7.4;cerebral cortex: 8.4;hippocampal formation: 4.8;hypothalamus: 3.8" HPA057058 Enhanced Supported "Nucleoplasm,Actin filaments" NA NA "Cluster 77: Intestine - Digestion" "Cluster 33: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" Nucleoplasm "Actin filaments" "HPA057058: " "unprognostic (5.14e-2)" "unprognostic (9.59e-3)" "potential prognostic favorable (2.27e-4)" "unprognostic (4.56e-2)" "unprognostic (4.45e-3)" "unprognostic (2.19e-2)" "unprognostic (2.98e-1)" "unprognostic (4.70e-2)" "unprognostic (2.96e-2)" ONECUT3 ENSG00000205922 "One cut homeobox 3" O60422 19 1753506-1780988 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "retina: 2.0;stomach 1: 4.1" "Cell type enriched" "Detected in some" 11 "Retinal horizontal cells: 342.6" "Cell type enhanced" "Detected in single" "splatter: 1.5" "Group enriched" "Detected in some" 7 "Pancreatic Adenocarcinoma (TCGA): 5.5;Stomach Adenocarcinoma (TCGA): 5.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 15.3" "Low region specificity" "Detected in single" "Region enhanced" "Detected in single" "hypothalamus: 2.4" HPA059936 Supported Nucleoplasm NA NA "Cluster 42: Retina - Visual perception" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 109: Neurons - Neuronal signaling" 3 Nucleoplasm "HPA059936: " "unprognostic (1.50e-1)" "unprognostic (3.82e-2)" "unprognostic (1.55e-1)" "unprognostic (1.11e-1)" OOEP "C6orf156, Em:AC019205.2, KHDC2" ENSG00000203907 "Oocyte expressed protein" A6NGQ2 6 73368555-73395133 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 13.3" "Cell type enhanced" "Detected in many" "Colonocytes: 771.2;Enteric stem cells: 1614.8;Enteric transient amplifying cells: 1261.5;Epididymal efferent duct absorptive cells: 714.2;Gastric chief cells: 1508.1;Goblet cells: 973.4;Mucous neck cells: 843.7;Paneth cells: 1086.7;Parietal cells: 1527.5" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in many" 25 "Testicular Germ Cell Tumor (TCGA): 33.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Adrenocortical cancer: 3.9" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA055165 Approved NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 6: Non-specific - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 15: Non-specific - Protein processing" 7 "HPA055165: " "unprognostic (9.43e-2)" "unprognostic (4.17e-1)" "unprognostic (6.97e-2)" "unprognostic (2.35e-1)" "unprognostic (1.16e-1)" "unprognostic (5.52e-2)" "unprognostic (4.70e-1)" OOSP1 ENSG00000284873 "Oocyte secreted protein 1" 11 59938432-59957480 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 1.2;Distal convoluted tubule cells: 1.0;Late spermatids: 1.2;Proximal tubule cells: 4.7" "Cell type enhanced" "Detected in many" "midbrain-derived inhibitory: 4.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 88: Proximal tubular cells - Transmembrane transport" OOSP2 "FLJ36198, OOSP2A, PLAC1L, TMEM122" ENSG00000149507 "Oocyte secreted protein 2" Q86WS3 11 60040409-60048044 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 17 "testis: 16.8" "Cell type enriched" "Detected in some" 13 "Oocytes: 175.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Sertoli cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA050914 Enhanced "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 57: Testis - Spermatogenesis" "Cluster 65: Non-specific - Unknown function" "Cluster 41: Oocytes - Oogenesis" 2 "HPA050914: " OOSP3 ENSG00000285231 "Oocyte secreted protein family member 3" A0A2R8YFM6 11 59878782-59896483 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Epididymal efferent duct ciliated cells: 38.6;Neutrophils: 10.0;Parietal cells: 3.5;Proximal tubule cells: 5.2;Sertoli cells: 8.4" "Cell type enhanced" "Detected in many" "midbrain-derived inhibitory: 7.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 33 "basophil: 5.4" "Lineage enriched" "Detected in single" 54 "granulocytes: 5.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted - unknown location" "No annotated function" NA NA "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 24: Neutrophils - Innate immunity signal integration" OOSP4A ENSG00000285010 "Oocyte secreted protein family member 4A" A0A2R8YFL7 11 59964033-59970343 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 23 "basophil: 7.5" "Lineage enriched" "Detected in single" 23 "granulocytes: 7.5" "Cancer enriched" "Detected in single" 11 "Leukemia: 1.0" "Secreted - unknown location" "No annotated function" NA NA "Cluster 47: Leukemia - Hemostasis" OOSP4B ENSG00000255393 "Oocyte secreted protein family member 4B" A0A2R8Y4Y8 11 59978020-60031077 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 40 "Oocytes: 23.0" "Cell type enhanced" "Detected in single" "midbrain-derived inhibitory: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted - unknown location" "No annotated function" NA NA "Cluster 41: Oocytes - Oogenesis" OPA1 "FLJ12460, KIAA0567, MGM1, NPG, NTG" ENSG00000198836 "OPA1 mitochondrial dynamin like GTPase" O60313 3 193593144-193697811 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Apoptosis, Sensory transduction, Vision" Hydrolase "Cardiomyopathy, Deafness, Disease variant, Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036926, HPA036927" Supported Supported Nucleoplasm,Mitochondria NA NA 7900 "Cluster 23: B-cells - Immunoglobulins" "Cluster 52: Non-specific - Cellular respiration" "Cluster 14: Neurons - Synaptic function" "Cluster 63: Non-specific - Protein processing" "Cluster 17: Non-specific - RNA processing" 23 "Nucleoplasm, Mitochondria" "HPA036926: , HPA036927: " "unprognostic (1.33e-1)" "unprognostic (7.16e-3)" "unprognostic (8.92e-2)" "unprognostic (6.46e-2)" "unprognostic (1.36e-1)" "unprognostic (1.79e-1)" "unprognostic (3.69e-2)" "unprognostic (3.92e-3)" "unprognostic (1.42e-2)" "unprognostic (2.46e-2)" "unprognostic (6.38e-3)" "unprognostic (1.03e-1)" "unprognostic (1.27e-1)" "unprognostic (2.86e-1)" "unprognostic (1.71e-2)" "potential prognostic unfavorable (6.65e-4)" "unprognostic (5.05e-3)" "unprognostic (5.21e-2)" "unprognostic (1.32e-1)" "unprognostic (4.90e-2)" "unprognostic (5.24e-3)" "potential prognostic unfavorable (8.92e-4)" "unprognostic (1.01e-1)" "unprognostic (4.65e-2)" "unprognostic (1.69e-2)" "unprognostic (1.14e-1)" "unprognostic (7.08e-2)" "unprognostic (1.84e-1)" "unprognostic (1.94e-1)" "potential prognostic unfavorable (7.07e-4)" "unprognostic (7.88e-2)" OPA3 "FLJ22187, MGA3" ENSG00000125741 "Outer mitochondrial membrane lipid metabolism regulator OPA3" Q9H6K4 19 45527767-45602212 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Sensory transduction, Vision" "Cataract, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 210.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044881 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 52: Non-specific - Cellular respiration" "Cluster 38: Sub-cortical - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 2 Cytosol Nucleoplasm "HPA044881: " "unprognostic (2.24e-2)" "unprognostic (5.05e-2)" "unprognostic (9.02e-2)" "unprognostic (1.40e-1)" "unprognostic (1.44e-1)" "unprognostic (1.05e-1)" "unprognostic (2.01e-1)" "unprognostic (2.47e-2)" "unprognostic (9.82e-3)" "unprognostic (7.14e-2)" "validated prognostic favorable (1.80e-6)" "validated prognostic favorable (2.07e-4)" "potential prognostic favorable (1.61e-5)" "potential prognostic unfavorable (8.27e-4)" "unprognostic (4.12e-2)" "unprognostic (2.79e-2)" "unprognostic (6.08e-2)" "unprognostic (9.88e-2)" "unprognostic (1.10e-1)" "unprognostic (2.27e-2)" "unprognostic (9.27e-2)" "unprognostic (1.28e-2)" "unprognostic (8.41e-2)" "unprognostic (2.24e-1)" "unprognostic (1.42e-1)" "unprognostic (4.49e-2)" "unprognostic (1.07e-2)" "unprognostic (1.78e-1)" "unprognostic (2.37e-1)" "unprognostic (3.52e-2)" "unprognostic (2.93e-2)" OPALIN "HTMP10, TMEM10, TMP10" ENSG00000197430 "Oligodendrocytic myelin paranodal and inner loop protein" Q96PE5 10 96343221-96359365 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 39 "brain: 139.3" "Cell type enriched" "Detected in some" 75 "Oligodendrocytes: 513.9" "Group enriched" "Detected in many" 21 "committed oligodendrocyte precursor: 180.8;oligodendrocyte: 469.7" "Cancer enriched" "Detected in single" 32 "Glioblastoma Multiforme (TCGA): 3.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in all" "white matter: 240.2" "Low region specificity" "Detected in all" HPA014372 Supported NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 6: Leukemia - Signal transduction" "Cluster 80: Oligodendrocytes - Myelination" "HPA014372: " "unprognostic (7.22e-2)" "unprognostic (2.86e-1)" OPCML "IGLON1, OBCAM, OPCM" ENSG00000183715 "Opioid binding protein/cell adhesion molecule like" Q14982 11 132414977-133532501 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 35.4;parathyroid gland: 9.7;retina: 10.5" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 2290.3;Brain inhibitory neurons: 1695.1;Corticotrophs: 2234.9;Oligodendrocyte progenitor cells: 5524.7;Oligodendrocytes: 902.6;Other brain neurons: 1159.7;Retinal amacrine cells: 544.9;Retinal bipolar cells: 956.6;Retinal ganglion cells: 888.4;Retinal pigment epithelial cells: 2067.5" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 7.1;Kidney Renal Clear Cell Carcinoma (TCGA): 2.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 1.6;thyroid cancer: 1.3" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Minor Salivary Gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" "Cell adhesion" NA NA 1300000 "Cluster 27: Cerebellum - Synaptic function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 35: Neurons - Synaptic function & neurogenesis" 3 "unprognostic (2.41e-1)" "unprognostic (7.23e-2)" "potential prognostic favorable (5.02e-4)" "potential prognostic favorable (5.92e-6)" "unprognostic (2.93e-3)" "unprognostic (1.45e-1)" OPHN1 "ARHGAP41, MRX60, OPN1" ENSG00000079482 "Oligophrenin 1" O60890 X 67949349-68433913 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Endocytosis, Neurogenesis" "GTPase activation" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 796.8;Fibro-adipogenic progenitors: 537.9;Oligodendrocyte progenitor cells: 1264.0;Prostatic glandular cells: 520.6;Syncytiotrophoblasts: 848.7" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 1199.3;oligodendrocyte precursor cell: 1506.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002919 Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 1 "Nucleoplasm, Plasma membrane" "HPA002919: " "unprognostic (3.40e-2)" "unprognostic (2.29e-2)" "unprognostic (1.68e-1)" "unprognostic (1.55e-1)" "unprognostic (5.57e-3)" "unprognostic (1.35e-1)" "validated prognostic favorable (9.09e-4)" "validated prognostic favorable (5.53e-5)" "unprognostic (3.41e-3)" "potential prognostic unfavorable (1.19e-4)" "unprognostic (2.64e-1)" "unprognostic (7.08e-3)" "unprognostic (4.40e-2)" "potential prognostic unfavorable (8.67e-4)" "unprognostic (2.00e-2)" "unprognostic (2.31e-2)" "unprognostic (1.13e-1)" "unprognostic (1.53e-2)" "unprognostic (3.29e-2)" "unprognostic (6.32e-2)" "unprognostic (1.37e-1)" "unprognostic (2.26e-1)" "unprognostic (4.44e-2)" "unprognostic (2.54e-2)" "unprognostic (1.39e-1)" "unprognostic (1.23e-1)" "unprognostic (2.30e-1)" "unprognostic (1.47e-1)" "unprognostic (9.01e-3)" "unprognostic (7.42e-3)" "unprognostic (4.73e-2)" OPLAH "5-Opase, OPLA" ENSG00000178814 "5-oxoprolinase, ATP-hydrolysing" O14841 8 144051266-144063965 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 62.9" "Group enriched" "Detected in many" 4 "Early spermatids: 133.9;Late spermatids: 400.1" "Cell type enhanced" "Detected in many" "astrocyte: 30.9;Bergmann glia: 14.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.1;neutrophil: 1.1" "Group enriched" "Detected in many" 9 "granulocytes: 1.1;monocytes: 1.1" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Spleen - Neutrophils_2, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026562, HPA028260, HPA052429" Uncertain Approved "Nucleoli fibrillar center" NA NA 12000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 79: Testis - Spermatogenesis" "Cluster 49: Hindbrain - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 3 "Nucleoli fibrillar center" "HPA026562: , HPA028260: , HPA052429: " "unprognostic (2.56e-1)" "unprognostic (1.38e-1)" "unprognostic (1.44e-1)" "unprognostic (8.13e-3)" "unprognostic (1.42e-1)" "unprognostic (1.53e-1)" "unprognostic (4.20e-2)" "potential prognostic unfavorable (2.15e-4)" "unprognostic (4.32e-2)" "unprognostic (1.89e-2)" "potential prognostic favorable (9.34e-4)" "unprognostic (3.26e-1)" "potential prognostic favorable (4.21e-5)" "unprognostic (2.46e-1)" "unprognostic (4.84e-2)" "unprognostic (1.60e-1)" "unprognostic (7.86e-3)" "unprognostic (6.33e-2)" "unprognostic (9.02e-2)" "unprognostic (1.56e-1)" "potential prognostic favorable (3.25e-4)" "unprognostic (7.39e-2)" "unprognostic (2.90e-2)" "unprognostic (1.41e-1)" "unprognostic (8.47e-2)" "unprognostic (5.54e-2)" "unprognostic (1.50e-1)" "unprognostic (9.02e-3)" "unprognostic (5.16e-1)" "unprognostic (5.06e-2)" "unprognostic (5.31e-2)" OPN1LW "CBBM, CBP, COD5, RCP" ENSG00000102076 "Opsin 1, long wave sensitive" P04000 X 154144243-154159032 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Sensory transduction, Vision" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 2378 "retina: 237.8" "Cell type enriched" "Detected in some" 206 "Cone photoreceptor cells: 1012.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 42: Retina - Visual perception" "Cluster 79: Photoreceptor cells - Phototransduction" 1 OPN1MW "CBBM, CBD, COD5, GCP, OPN1MW1" ENSG00000268221 "Opsin 1, medium wave sensitive" P04001 X 154182596-154196861 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Sensory transduction, Vision" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 93 "retina: 12.6" "Cell type enriched" "Detected in single" 67 "Cone photoreceptor cells: 29.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 42: Retina - Visual perception" "Cluster 72: Neuronal - Signal transduction" "Cluster 79: Photoreceptor cells - Phototransduction" OPN1MW2 ENSG00000166160 "Opsin 1, medium wave sensitive 2" P0DN77 X 154219756-154233286 "Predicted membrane proteins" "Sensory transduction, Vision" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OPN1MW3 ENSG00000269433 "Opsin 1, medium wave sensitive 3" P0DN78 X 154257582-154271090 "Predicted membrane proteins" "Sensory transduction, Vision" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 449 "retina: 44.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 42: Retina - Visual perception" "Cluster 72: Neuronal - Signal transduction" OPN1SW "BCP, BOP, CBT" ENSG00000128617 "Opsin 1, short wave sensitive" P03999 7 128772485-128775794 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Sensory transduction, Vision" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 181 "retina: 38.0" "Cell type enriched" "Detected in some" 8 "Cone photoreceptor cells: 182.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA013562, HPA014083" Enhanced NA NA "Cluster 42: Retina - Visual perception" "Cluster 48: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 79: Photoreceptor cells - Phototransduction" "HPA013562: , HPA014083: " "unprognostic (7.37e-2)" "unprognostic (1.87e-2)" OPN3 "ECPN, encephalopsin, ERO, NMO-1, PPP1R116" ENSG00000054277 "Opsin 3" Q9H1Y3 1 241590102-241677376 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 17.6" "Cell type enhanced" "Detected in many" "cDC: 115.7;Early spermatids: 197.8;Extravillous trophoblasts: 377.6;Late spermatids: 160.0;Migrating cytotrophoblasts: 142.3;pDCs: 172.3;Syncytiotrophoblasts: 187.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "plasmacytoid DC: 10.0" "Lineage enriched" "Detected in many" 5 "dendritic cells: 10.0" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Pituitary gland - Somatotropes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "CAB013682, HPA049243" Uncertain Approved "Nucleoplasm,Plasma membrane,Primary cilium,Basal body,Cytosol" NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 53: Neurons - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 1 "Nucleoplasm, Cytosol" "Plasma membrane, Primary cilium, Basal body" "CAB013682: , HPA049243: " "unprognostic (4.16e-3)" "unprognostic (9.55e-2)" "unprognostic (3.63e-1)" "unprognostic (9.63e-3)" "unprognostic (4.10e-2)" "unprognostic (9.94e-2)" "potential prognostic unfavorable (3.04e-4)" "unprognostic (5.57e-2)" "unprognostic (4.05e-2)" "unprognostic (2.82e-1)" "unprognostic (2.51e-2)" "unprognostic (4.55e-3)" "unprognostic (2.27e-1)" "potential prognostic unfavorable (1.11e-4)" "unprognostic (2.00e-1)" "potential prognostic unfavorable (3.66e-4)" "unprognostic (1.57e-1)" "unprognostic (2.98e-2)" "unprognostic (6.93e-2)" "unprognostic (2.19e-1)" "unprognostic (5.79e-2)" "unprognostic (2.01e-2)" "unprognostic (6.20e-2)" "unprognostic (2.05e-1)" "unprognostic (1.06e-1)" "unprognostic (1.01e-1)" "unprognostic (1.59e-1)" "potential prognostic unfavorable (6.37e-4)" "unprognostic (5.79e-2)" "unprognostic (9.97e-2)" "unprognostic (3.15e-1)" OPN4 "melanopsin, MOP" ENSG00000122375 "Opsin 4" Q9UHM6 10 86654518-86666460 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Biological rhythms, Sensory transduction" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 1.2;brain: 1.1;skeletal muscle: 1.4" "Group enriched" "Detected in some" 8 "Brain excitatory neurons: 3.2;Brain inhibitory neurons: 9.7" "Cell type enhanced" "Detected in many" "eccentric medium spiny neuron: 17.2;medium spiny neuron: 19.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Pituitary gland - Gonadotropes" "Not detected" "Not detected" "Not detected" "Not detected" HPA039147 Approved NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 33: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 35: Neurons - Synaptic function & neurogenesis" 1 "HPA039147: " OPN5 "dJ402H5.1, neuropsin, TMEM13" ENSG00000124818 "Opsin 5" Q6U736 6 47781982-47832780 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Vision" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "testis: 2.4" "Group enriched" "Detected in some" 4 "Early spermatids: 32.9;Late primary spermatocytes: 49.7;Late spermatids: 48.5;Myosatellite cells: 30.8" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 6.8;LAMP5-LHX6 and Chandelier: 9.0;mammillary body: 7.4;midbrain-derived inhibitory: 7.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA026084 Supported NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 2 "HPA026084: " OPRD1 ENSG00000116329 "Opioid receptor delta 1" P41143 1 28812170-28871267 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 2.7" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 21.3;Brain excitatory neurons: 16.7;Brain inhibitory neurons: 17.7;Epicardial cells: 4.5;Lactotrophs: 4.4;Other brain neurons: 27.8;Pancreatic islet cells: 9.3;Retinal bipolar cells: 8.8;Undifferentiated spermatogonia: 4.8" "Cell type enhanced" "Detected in many" "MGE interneuron: 72.6" "Cancer enhanced" "Detected in single" "Skin Cutaneous Melanoma (TCGA): 2.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 7.1;skin cancer: 4.4" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Kidney - Proximal tubular cells, Pancreas - Beta cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA070831 Approved NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 24: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 35: Neurons - Synaptic function & neurogenesis" 13 "HPA070831: " "unprognostic (3.13e-1)" "unprognostic (1.53e-1)" "potential prognostic favorable (2.59e-4)" "unprognostic (2.22e-2)" "unprognostic (5.15e-2)" OPRK1 "KOR, OPRK" ENSG00000082556 "Opioid receptor kappa 1" P41145 8 53225724-53251637 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" Behavior "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.8;prostate: 1.5" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 5.3;Brain inhibitory neurons: 14.9;Endometrial glandular cells: 9.6;Endometrial luminal cells: 12.8;Extravillous trophoblasts: 13.5;Leydig cells: 5.5;Other brain neurons: 17.2;Pituicytes/FSCs: 5.1;Prostatic glandular cells: 22.1" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Prostate Adenocarcinoma (TCGA): 3.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 2.1;prostate cancer: 3.8" "Colon - Colon enteroendocrine cells, Minor Salivary Gland - Adipocytes (Minor salivary gland), Prostate - Prostate glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA067549 Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 24: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 35: Neurons - Synaptic function & neurogenesis" 6 "Plasma membrane" "Nucleoplasm, Cytosol" "HPA067549: " "unprognostic (2.87e-1)" "unprognostic (2.15e-2)" "unprognostic (8.42e-2)" OPRL1 "KOR-3, NOCIR, NOPr, OOR, ORL1, PNOCR" ENSG00000125510 "Opioid related nociceptin receptor 1" P41146 20 64080082-64100643 "G-protein coupled receptors, Predicted membrane proteins" Behavior "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 12.1;lymphoid tissue: 3.8;testis: 6.0" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 6.9;Brain inhibitory neurons: 8.4;Ependymal cells: 1.8;Microglia: 6.1;Neutrophils: 2.6;Other brain neurons: 11.9" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 3.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "classical monocyte: 3.9;eosinophil: 5.8;intermediate monocyte: 5.5;myeloid DC: 4.7;neutrophil: 4.9;non-classical monocyte: 12.5" "Group enriched" "Detected in many" 11 "dendritic cells: 4.7;granulocytes: 5.8;monocytes: 12.5" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064863 Approved "Primary cilium,Primary cilium tip" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 98: Neurons - Neurotransmission & signaling" 5 "Primary cilium, Primary cilium tip" "HPA064863: " "unprognostic (2.42e-1)" "potential prognostic unfavorable (5.72e-4)" "unprognostic (6.59e-2)" "unprognostic (3.65e-1)" "unprognostic (2.78e-1)" "unprognostic (1.09e-1)" "unprognostic (9.54e-2)" "unprognostic (4.49e-2)" "unprognostic (5.52e-2)" OPRM1 "MOP, MOR1" ENSG00000112038 "Opioid receptor mu 1" P35372 6 154010496-154246867 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.4;testis: 2.6" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 106.4;Brain excitatory neurons: 92.8;Brain inhibitory neurons: 102.1;Early spermatids: 70.1;Innate lymphoid cells: 48.2;Late primary spermatocytes: 74.3;Late spermatids: 76.5;Microglia: 152.3;NK-cells: 46.7;Other brain neurons: 100.3;Renal collecting duct intercalated cells: 41.0;T-cells: 69.5" "Cell type enhanced" "Detected in all" "eccentric medium spiny neuron: 374.0" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in single" 7 "Neuroblastoma: 4.3" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA014509, HPA067435" Enhanced Supported NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 39 "HPA014509: , HPA067435: " "unprognostic (5.81e-2)" "unprognostic (3.24e-3)" "unprognostic (1.35e-1)" OPRPN "BPLP, PRL1, PROL1" ENSG00000171199 "Opiorphin prepropeptide" Q99935 4 70397931-70410195 "Predicted secreted proteins" "Protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "salivary gland: 145.4" "Cell type enriched" "Detected in some" 285 "Lacrimal acinar cells: 32939.5" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Breast Invasive Carcinoma (TCGA): 11.9;Liver Hepatocellular Carcinoma (TCGA): 7.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Eccrine sweat gland cells, Testis - Late spermatids" HPA065711 Approved "Secreted in other tissues" "Enzyme inhibitor" NA NA 33000 "Cluster 82: Salivary gland - Secretion" "Cluster 15: Kidney cancer - Membrane components" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 3 "HPA065711: " "unprognostic (7.95e-3)" "unprognostic (1.29e-1)" OPTC ENSG00000188770 Opticin Q9UBM4 1 203494153-203508949 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 5 "Epicardial cells: 20.5" "Group enriched" "Detected in some" 7 "committed oligodendrocyte precursor: 1.6;oligodendrocyte precursor cell: 3.5" "Cancer enriched" "Detected in single" 7 "Testicular Germ Cell Tumor (TCGA): 2.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA034951, HPA034952" Enhanced "Secreted in other tissues" "No annotated function" NA NA "Cluster 47: Endothelial cells - Vasculature" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" "HPA034951: , HPA034952: " "unprognostic (4.02e-2)" OPTN "FIP-2, FIP2, GLC1E, HIP7, HYPL, NRP, TFIIIA-INTP" ENSG00000123240 Optineurin Q96CV9 10 13099449-13138308 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Autophagy, Host-virus interaction, Immunity, Innate immunity" "Amyotrophic lateral sclerosis, Disease variant, Glaucoma, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "skeletal muscle: 835.6;tongue: 368.6" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 444.3;Late spermatids: 1618.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003279, HPA003360, CAB019303" Approved Enhanced Cytosol NA NA 2400000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 53: Neurons - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 238 Cytosol "CAB019303: , HPA003279: , HPA003360: " "unprognostic (8.12e-3)" "unprognostic (6.08e-2)" "unprognostic (2.56e-1)" "unprognostic (1.62e-1)" "unprognostic (1.75e-2)" "unprognostic (2.31e-3)" "unprognostic (8.63e-2)" "unprognostic (4.84e-3)" "unprognostic (4.56e-2)" "unprognostic (1.12e-1)" "potential prognostic favorable (1.48e-4)" "unprognostic (3.74e-3)" "unprognostic (3.93e-2)" "potential prognostic unfavorable (1.45e-4)" "unprognostic (5.71e-3)" "unprognostic (6.68e-2)" "unprognostic (3.50e-3)" "unprognostic (5.11e-2)" "unprognostic (1.76e-1)" "unprognostic (1.21e-1)" "unprognostic (5.75e-2)" "unprognostic (1.08e-2)" "unprognostic (1.01e-3)" "unprognostic (3.24e-1)" "unprognostic (2.22e-2)" "unprognostic (4.08e-2)" "unprognostic (1.11e-2)" "unprognostic (2.08e-1)" "unprognostic (1.64e-1)" "unprognostic (1.45e-1)" "unprognostic (2.49e-2)" OR10A2 "OR10A2P, OST363" ENSG00000170790 "Olfactory receptor family 10 subfamily A member 2" Q9H208 11 6863057-6874717 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Adipocytes: 1.8;Brain inhibitory neurons: 1.1;Cone photoreceptor cells: 4.1;Epicardial cells: 4.5;Plasma cells: 1.6;Retinal ganglion cells: 3.9" "Low cell type specificity" "Detected in some" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 32: Cerebral cortex - Mixed function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" OR10A3 "HSHTPCRX12, HTPCRX12" ENSG00000170683 "Olfactory receptor family 10 subfamily A member 3" P58181 11 7937171-7941708 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR10A4 OR10A4P ENSG00000170782 "Olfactory receptor family 10 subfamily A member 4" Q9H209 11 6876625-6877619 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 32: Cerebral cortex - Mixed function" OR10A5 "JCG6, OR10A1, OR11-403" ENSG00000166363 "Olfactory receptor family 10 subfamily A member 5" Q9H207 11 6845683-6846636 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 32: Cerebral cortex - Mixed function" OR10A6 ENSG00000279000 "Olfactory receptor family 10 subfamily A member 6 (gene/pseudogene)" Q8NH74 11 7924592-7931268 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 9: Non-specific - Receptor signaling" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" OR10A7 ENSG00000179919 "Olfactory receptor family 10 subfamily A member 7" Q8NGE5 12 55221025-55221975 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA055111 Uncertain NA NA "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" "HPA055111: " OR10AC1 OR10AC1P ENSG00000176510 "Olfactory receptor family 10 subfamily AC member 1 (gene/pseudogene)" 7 143509256-143519469 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.7" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "fibroblast: 1.6;leukocyte: 2.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 80: Thymus - Adaptive immune response" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 102: Non-specific - Mixed function" OR10AD1 OR10AD1P ENSG00000172640 "Olfactory receptor family 10 subfamily AD member 1" Q8NGE0 12 48202339-48203292 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "retina: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA049913 Uncertain NA NA "Cluster 42: Retina - Visual perception" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "HPA049913: " "unprognostic (8.81e-2)" OR10AG1 ENSG00000174970 "Olfactory receptor family 10 subfamily AG member 1" Q8NH19 11 55965755-55969945 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 98: Neurons - Neurotransmission & signaling" 4 OR10C1 "hs6M1-17, OR10C1P, OR10C2" ENSG00000206474 "Olfactory receptor family 10 subfamily C member 1" Q96KK4 6 29439306-29440977 "Essential proteins, G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 10 "Ependymal cells: 1.0" "Cell type enhanced" "Detected in single" "ependymal cell: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA049336 Uncertain NA NA "Cluster 34: Ciliated cells - Cilia assembly & function" "HPA049336: " OR10D3 "HTPCRX09, OR10D3P" ENSG00000197309 "Olfactory receptor family 10 subfamily D member 3" Q8NH80 11 124183345-124188780 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 1.4;Early primary spermatocytes: 2.3;Other brain neurons: 1.2;Undifferentiated spermatogonia: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 109: Neurons - Neuronal signaling" OR10G2 ENSG00000255582 "Olfactory receptor family 10 subfamily G member 2" Q8NGC3 14 21633836-21634940 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pituitary gland - Corticotropes" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 59: Leukemia - T-cell receptor" OR10G3 ENSG00000169208 "Olfactory receptor family 10 subfamily G member 3" Q8NGC4 14 21568520-21580076 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 11 "Corticotrophs: 29.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pituitary gland - Corticotropes" "Not detected" "Not detected" "Not detected" "Not detected" HPA019766 Uncertain NA NA "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 56: Non-specific - Sensory perception" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" "HPA019766: " OR10G4 ENSG00000254737 "Olfactory receptor family 10 subfamily G member 4" Q8NGN3 11 124012997-124018732 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Pancreatic acinar cells: 1.3;Sertoli cells: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 9: Non-specific - Receptor signaling" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" "unprognostic (2.73e-2)" OR10G6 "OR10G6P, OR10G6Q" ENSG00000198674 "Olfactory receptor family 10 subfamily G member 6" Q8NH81 11 123994163-123995161 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" OR10G7 ENSG00000182634 "Olfactory receptor family 10 subfamily G member 7" Q8NGN6 11 124036013-124041325 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" OR10G8 ENSG00000234560 "Olfactory receptor family 10 subfamily G member 8" Q8NGN5 11 124026798-124030634 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" OR10G9 OR10G10P ENSG00000236981 "Olfactory receptor family 10 subfamily G member 9" Q8NGN4 11 124023013-124023948 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR10H1 ENSG00000186723 "Olfactory receptor family 10 subfamily H member 1" Q9Y4A9 19 15804549-15815664 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 5 "Urothelial cells: 28.9" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Prostate - Prostate glandular cells" NA NA "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 69: Urothelial cells - Basic cellular functions" 3 "unprognostic (1.33e-1)" "unprognostic (4.25e-2)" "unprognostic (1.91e-2)" "unprognostic (2.38e-1)" "unprognostic (4.44e-2)" OR10H2 ENSG00000171942 "Olfactory receptor family 10 subfamily H member 2" O60403 19 15728024-15729052 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 2 OR10H3 ENSG00000171936 "Olfactory receptor family 10 subfamily H member 3" O60404 19 15737985-15742343 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 108: Fibroblasts - ECM organization" OR10H4 ENSG00000176231 "Olfactory receptor family 10 subfamily H member 4" Q8NGA5 19 15944299-15950350 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR10H5 ENSG00000172519 "Olfactory receptor family 10 subfamily H member 5" Q8NGA6 19 15787661-15800357 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Epicardial cells: 2.3;Gastric chief cells: 1.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.2" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" NA NA "Cluster 48: Non-specific - Mixed function" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" "unprognostic (1.87e-2)" "unprognostic (7.46e-3)" "unprognostic (9.88e-2)" OR10J1 "HGMP07J, HSHGMP07J" ENSG00000196184 "Olfactory receptor family 10 subfamily J member 1" P30954 1 159437845-159443078 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 67 "testis: 6.6" "Group enriched" "Detected in some" 13 "Early spermatids: 41.0;Late primary spermatocytes: 45.7;Late spermatids: 81.0" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 48: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" OR10J3 OR10J3P ENSG00000196266 "Olfactory receptor family 10 subfamily J member 3" 1 159313720-159314659 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 50: Lymphoma - Unknown function" OR10J4 "OR10J4P, OST717" ENSG00000249730 "Olfactory receptor family 10 subfamily J member 4 (gene/pseudogene)" 1 159432204-159433138 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" OR10J5 ENSG00000184155 "Olfactory receptor family 10 subfamily J member 5" Q8NHC4 1 159535078-159536007 "G-protein coupled receptors, Predicted membrane proteins" "Angiogenesis, Myogenesis, Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR10K1 ENSG00000173285 "Olfactory receptor family 10 subfamily K member 1" Q8NGX5 1 158461574-158470857 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Kupffer cells: 1.0" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA059125 Uncertain NA NA "Cluster 48: Non-specific - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 94: Gonadal somatic cells - Mixed function" "HPA059125: " "unprognostic (6.60e-2)" "unprognostic (3.05e-2)" "unprognostic (2.38e-1)" "unprognostic (2.22e-2)" OR10K2 ENSG00000180708 "Olfactory receptor family 10 subfamily K member 2" Q6IF99 1 158418210-158426237 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA059125 Uncertain NA NA "Cluster 82: Dendritic cells - Antigen presentation" "HPA059125: " OR10P1 "OR10P1P, OR10P2P, OR10P3P, OST701" ENSG00000175398 "Olfactory receptor family 10 subfamily P member 1" Q8NGE3 12 55636892-55637833 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA074114 Supported "Plasma membrane" NA NA "Cluster 50: Lymphoma - Unknown function" "Plasma membrane" "HPA074114: " OR10Q1 ENSG00000180475 "Olfactory receptor family 10 subfamily Q member 1" Q8NGQ4 11 58227882-58228918 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA046968 Uncertain Approved "Mid piece" NA NA "Cluster 15: Kidney cancer - Membrane components" "Mid piece" "HPA046968: " OR10R2 OR10R2Q ENSG00000198965 "Olfactory receptor family 10 subfamily R member 2" 1 158472220-158480936 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 29 "Leukemia: 2.8" "Not detected" "Not detected" "HPA059775, HPA060399" Uncertain NA NA "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" "HPA059775: , HPA060399: " OR10S1 ENSG00000196248 "Olfactory receptor family 10 subfamily S member 1" 11 123976661-123977781 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR10T2 ENSG00000186306 "Olfactory receptor family 10 subfamily T member 2" Q8NGX3 1 158398522-158399466 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 59: Leukemia - T-cell receptor" OR10V1 ENSG00000172289 "Olfactory receptor family 10 subfamily V member 1" Q8NGI7 11 59712916-59713845 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA060076 Uncertain NA NA "Cluster 89: Adipocytes - Lipid metabolism" "HPA060076: " OR10W1 OR10W1P ENSG00000172772 "Olfactory receptor family 10 subfamily W member 1" Q8NGF6 11 58266792-58268260 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR10X1 OR10X1P ENSG00000279111 "Olfactory receptor family 10 subfamily X member 1" Q8NGY0 1 158578919-158579899 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR10Z1 ENSG00000198967 "Olfactory receptor family 10 subfamily Z member 1" Q8NGY1 1 158605268-158612514 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 21 "bone marrow: 7.1" "Cell type enhanced" "Detected in single" "Erythrocyte progenitors: 2.8" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Erythroid cells, Spleen - Erythrocytes, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 15: Bone marrow - Innate immune response" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 47: Leukemia - Hemostasis" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" OR11A1 "hs6M1-18, OR11A2" ENSG00000204694 "Olfactory receptor family 11 subfamily A member 1" Q9GZK7 6 29425504-29457071 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "Early spermatids: 2.2;Ependymal cells: 5.4;Late spermatids: 4.2" "Group enriched" "Detected in some" 7 "ependymal cell: 8.4;hippocampal dentate gyrus: 5.0" "Not detected" "Not detected" "Region enhanced" "Detected in single" "medulla oblongata: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 46: Brainstem - Mixed function" "Cluster 34: Ciliated cells - Cilia assembly & function" OR11G2 ENSG00000196832 "Olfactory receptor family 11 subfamily G member 2" 14 20190896-20201075 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Epicardial cells: 2.3;Gastric chief cells: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 5 "neutrophil: 2.2" "Lineage enriched" "Detected in single" 13 "granulocytes: 2.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" OR11H1 OR22-1 ENSG00000130538 "Olfactory receptor family 11 subfamily H member 1" 22 15528192-15529139 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR11H12 ENSG00000257115 "Olfactory receptor family 11 subfamily H member 12" B2RN74 14 18601117-18602097 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047370 Uncertain NA NA "HPA047370: " OR11H2 "C14orf15, OR11H2P, OR11H8P" ENSG00000258453 "Olfactory receptor family 11 subfamily H member 2" Q8NH07 14 19712904-19714332 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047370 Uncertain NA NA "Cluster 103: Non-specific - Basic cellular processes" "HPA047370: " OR11H4 ENSG00000176198 "Olfactory receptor family 11 subfamily H member 4" 14 20239286-20244349 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Gastric chief cells: 1.1;Sertoli cells: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA052790 Uncertain NA NA "Cluster 61: BICR 18 - Protein kinases" "Cluster 82: Dendritic cells - Antigen presentation" "HPA052790: " OR11H6 ENSG00000176219 "Olfactory receptor family 11 subfamily H member 6" Q8NGC7 14 20223710-20224702 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR11H7 OR11H7P ENSG00000258806 "Olfactory receptor family 11 subfamily H member 7 (gene/pseudogene)" 14 20229402-20230346 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Esophageal cancer: 1.6" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 53: Squamous epithelial cells - Keratinization" OR11L1 ENSG00000197591 "Olfactory receptor family 11 subfamily L member 1" Q8NGX0 1 247840928-247841896 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR12D1 "hs6M1-19, OR12D1P" ENSG00000251608 "Olfactory receptor family 12 subfamily D member 1 (gene/pseudogene)" 6 29414928-29418905 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 75 "Ependymal cells: 16.6" "Cell type enriched" "Detected in some" 6 "ependymal cell: 13.7" "Region enhanced" "Detected in single" "medulla oblongata: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 46: Brainstem - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 34: Ciliated cells - Cilia assembly & function" OR12D2 hs6M1-20 ENSG00000280236 "Olfactory receptor family 12 subfamily D member 2" P58182 6 29395631-29398008 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 80 "Ependymal cells: 8.0" "Cell type enriched" "Detected in single" 19 "ependymal cell: 7.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 46: Brainstem - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 34: Ciliated cells - Cilia assembly & function" OR12D3 hs6M1-27 ENSG00000112462 "Olfactory receptor family 12 subfamily D member 3" Q9UGF7 6 29373423-29375291 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR13A1 ENSG00000256574 "Olfactory receptor family 13 subfamily A member 1" Q8NGR1 10 45302298-45315608 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "urinary bladder: 1.0" "Cell type enhanced" "Detected in single" "Papillary tip epithelial cells: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 16 "lymphoma: 4.1" "Spleen - B-cells (Spleen)" "Not detected" "Not detected" "Not detected" "Not detected" HPA057237 Uncertain NA NA "Cluster 64: Non-specific - Transcription" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" "HPA057237: " OR13C2 ENSG00000276119 "Olfactory receptor family 13 subfamily C member 2" Q8NGS9 9 104604671-104605627 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA078297 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 49: Hindbrain - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Plasma membrane" Nucleoplasm "HPA078297: " OR13C3 ENSG00000204246 "Olfactory receptor family 13 subfamily C member 3" 9 104535749-104536856 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 24: Neurons - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 109: Neurons - Neuronal signaling" OR13C4 ENSG00000148136 "Olfactory receptor family 13 subfamily C member 4" Q8NGS5 9 104526253-104527209 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 24: Neurons - Mixed function" "Cluster 109: Neurons - Neuronal signaling" OR13C5 ENSG00000277556 "Olfactory receptor family 13 subfamily C member 5" Q8NGS8 9 104598457-104599413 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA078297 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 49: Hindbrain - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" "Plasma membrane" Nucleoplasm "HPA078297: " OR13C7 "OR13C7P, OST706" ENSG00000243641 "Olfactory receptor family 13 subfamily C member 7 (gene/pseudogene)" 9 36002909-36003867 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 27: Breast cancer - Unknown function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" OR13C8 ENSG00000186943 "Olfactory receptor family 13 subfamily C member 8" Q8NGS7 9 104569168-104570130 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR13C9 ENSG00000136839 "Olfactory receptor family 13 subfamily C member 9" Q8NGT0 9 104617248-104618204 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA078297 Uncertain "Nucleoplasm,Plasma membrane" NA NA "Cluster 24: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Plasma membrane" Nucleoplasm "HPA078297: " OR13D1 ENSG00000179055 "Olfactory receptor family 13 subfamily D member 1" 9 104694518-104695462 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 24: Neurons - Mixed function" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" OR13F1 ENSG00000186881 "Olfactory receptor family 13 subfamily F member 1" Q8NGS4 9 104504263-104505222 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 24: Neurons - Mixed function" "Cluster 82: Dendritic cells - Antigen presentation" OR13G1 ENSG00000197437 "Olfactory receptor family 13 subfamily G member 1" Q8NGZ3 1 247670812-247679739 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Adipocytes: 2.8;Epicardial cells: 2.3;Hematopoietic stem cells: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 89: Adipocytes - Lipid metabolism" OR13H1 ENSG00000171054 "Olfactory receptor family 13 subfamily H member 1" Q8NG92 X 131544074-131545000 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 56: Non-specific - Sensory perception" OR13J1 ENSG00000168828 "Olfactory receptor family 13 subfamily J member 1" Q8NGT2 9 35869463-35870401 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 53: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" OR14A16 OR5AT1 ENSG00000196772 "Olfactory receptor family 14 subfamily A member 16" Q8NHC5 1 247814660-247824119 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Cone photoreceptor cells: 4.1;Tuft cells: 11.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 95: Tuft cells - Chemosensory signaling" OR14A2 "OR5AX1, OR5AX1P" ENSG00000241128 "Olfactory receptor family 14 subfamily A member 2" Q96R54 1 247722957-247748141 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 27 "testis: 2.7" "Cell type enhanced" "Detected in some" "Adipocytes: 7.4;Early spermatids: 17.0;Epicardial cells: 4.5;Hematopoietic stem cells: 5.3;Late primary spermatocytes: 29.8;Late spermatids: 6.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" HPA052685 Uncertain NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 72: Neuronal - Signal transduction" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" "HPA052685: " OR14C36 OR5BF1 ENSG00000177174 "Olfactory receptor family 14 subfamily C member 36" Q8NHC7 1 248348775-248349713 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 65: Non-specific - Unknown function" 1 OR14I1 "OR5BU1, OR5BU1P" ENSG00000189181 "Olfactory receptor family 14 subfamily I member 1" A6ND48 1 248681322-248682328 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 16 "Brain excitatory neurons: 2.1;Brain inhibitory neurons: 1.2" "Cell type enhanced" "Detected in some" "deep-layer intratelencephalic: 5.2;upper-layer intratelencephalic: 7.8" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "amygdala: 3.3;basal ganglia: 2.6;cerebral cortex: 4.7;hippocampal formation: 2.7;white matter: 4.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 53: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 35: Neurons - Synaptic function & neurogenesis" 1 OR14J1 "hs6M1-28, OR5U1" ENSG00000204695 "Olfactory receptor family 14 subfamily J member 1" Q9UGF5 6 29301701-29313017 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "retina: 1.7" "Cell type enriched" "Detected in single" 97 "Ependymal cells: 63.3" "Cell type enriched" "Detected in some" 9 "ependymal cell: 67.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in some" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" NA NA "Cluster 40: Non-specific - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 56: Non-specific - Sensory perception" "Cluster 34: Ciliated cells - Cilia assembly & function" "unprognostic (7.86e-2)" "unprognostic (1.10e-1)" "unprognostic (1.72e-3)" "unprognostic (1.76e-2)" "unprognostic (3.53e-1)" "unprognostic (2.52e-1)" "unprognostic (1.73e-2)" OR14K1 OR5AY1 ENSG00000153230 "Olfactory receptor family 14 subfamily K member 1" Q8NGZ2 1 247738615-247739559 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA016643 Uncertain NA NA "Cluster 72: Neuronal - Signal transduction" "HPA016643: " OR14L1P "OR5AV1, OR5AV1P" ENSG00000198452 "Olfactory receptor family 14 subfamily L member 1 pseudogene" 1 247617143-247622372 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Early spermatids: 1.7;Hematopoietic stem cells: 1.9;Late spermatids: 3.1;Mast cells: 8.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 53 "basophil: 5.3" "Lineage enriched" "Detected in single" 53 "granulocytes: 5.3" "Not detected" "Not detected" "Adipose subcutaneous - Mast cells, Colon - Mast cells, Minor Salivary Gland - Mast cells, Testis - Early spermatids" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 49: HMC-1 - Innate immune response" "Cluster 58: Mast cells - Allergic inflammatory responses" "unprognostic (8.83e-2)" OR1A1 OR17-7 ENSG00000172146 "Olfactory receptor family 1 subfamily A member 1" Q9P1Q5 17 3207539-3218896 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "retina: 1.3" "Cell type enhanced" "Detected in some" "Kupffer cells: 1.0;Thymocytes: 2.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in some" NA NA "Cluster 40: Non-specific - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 56: Non-specific - Sensory perception" "Cluster 46: Skeletal myocytes - Muscle structure & formation" "unprognostic (6.44e-2)" "unprognostic (2.27e-2)" "unprognostic (1.84e-2)" "unprognostic (3.69e-1)" "unprognostic (1.42e-1)" OR1A2 OR17-6 ENSG00000172150 "Olfactory receptor family 1 subfamily A member 2" Q9Y585 17 3197519-3198448 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR1B1 OR9-B ENSG00000280094 "Olfactory receptor family 1 subfamily B member 1" Q8NGR6 9 122628125-122657627 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 2.1;Conjunctival goblet cells: 1.9;Corticotrophs: 2.4;Fibro-adipogenic progenitors: 1.9;Hematopoietic stem cells: 3.9;Mast cells: 3.4;Oocytes: 4.6;Pituicytes/FSCs: 2.1;Retinal horizontal cells: 2.0;Retinal pigment epithelial cells: 4.3;Rod photoreceptor cells: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 53: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 58: Mast cells - Allergic inflammatory responses" OR1C1 "HSTPCR27, TPCR27" ENSG00000221888 "Olfactory receptor family 1 subfamily C member 1" Q15619 1 247754846-247760556 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Adipocytes: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 9: Non-specific - Receptor signaling" "Cluster 89: Adipocytes - Lipid metabolism" OR1D2 "OLFR1, OR17-4" ENSG00000184166 "Olfactory receptor family 1 subfamily D member 2" P34982 17 3088484-3104422 "Essential proteins, G-protein coupled receptors, Predicted membrane proteins" "Chemotaxis, Fertilization, Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Group enriched" "Detected in some" 6 "Early primary spermatocytes: 2.4;Early spermatids: 2.4;Epididymal clear cells: 2.0" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA "Cluster 40: Non-specific - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 3: Rhabdoid - Membrane components" "Cluster 46: Skeletal myocytes - Muscle structure & formation" "unprognostic (2.29e-1)" "unprognostic (2.33e-1)" "unprognostic (7.01e-2)" "unprognostic (4.36e-2)" "unprognostic (2.13e-2)" "unprognostic (5.07e-2)" "unprognostic (4.28e-1)" "unprognostic (9.00e-2)" OR1D5 OR17-31 ENSG00000262628 "Olfactory receptor family 1 subfamily D member 5" P58170 17 3062669-3063607 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA OR1E1 "HGM071, OR13-66, OR17-2, OR17-32, OR1E5, OR1E6, OR1E9P" ENSG00000180016 "Olfactory receptor family 1 subfamily E member 1" P30953 17 3397104-3398410 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 8 "Oocytes: 4.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 38: Sub-cortical - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 41: Oocytes - Oogenesis" OR1E2 "OR17-135, OR17-93, OR1E4" ENSG00000127780 "Olfactory receptor family 1 subfamily E member 2" P47887 17 3432870-3433841 "Essential proteins, G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" OR1F1 "Olfmf, OR16-36, OR16-37, OR16-88, OR16-89, OR16-90, OR1F10, OR1F13P, OR1F4, OR1F5, OR1F6, OR1F7, OR1F8, OR1F9, OR3-145" ENSG00000168124 "Olfactory receptor family 1 subfamily F member 1" O43749 16 3188204-3224779 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 5 "brain: 3.2" "Group enriched" "Detected in some" 5 "Early spermatids: 42.5;Late spermatids: 56.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 27: Cerebellum - Synaptic function" "Cluster 37: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" OR1G1 "OR17-209, OR1G2" ENSG00000183024 "Olfactory receptor family 1 subfamily G member 1" P47890 17 3126610-3127551 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR1I1 "OR19-20, OR1I1P, OR1I1Q" ENSG00000094661 "Olfactory receptor family 1 subfamily I member 1" O60431 19 15082211-15092970 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Cone photoreceptor cells: 2.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 56: Non-specific - Sensory perception" "Cluster 79: Photoreceptor cells - Phototransduction" "unprognostic (9.10e-2)" "unprognostic (4.71e-3)" "unprognostic (2.25e-1)" OR1J1 hg32 ENSG00000136834 "Olfactory receptor family 1 subfamily J member 1" Q8NGS3 9 122476958-122477926 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "spinal cord: 1.3" NA NA "Cluster 53: Neurons - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" OR1J2 "OR1J3, OR1J5, OST044" ENSG00000197233 "Olfactory receptor family 1 subfamily J member 2" Q8NGS2 9 122510802-122511743 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR1J4 "HSHTPCRX01, HTPCRX01" ENSG00000239590 "Olfactory receptor family 1 subfamily J member 4" Q8NGS1 9 122519141-122520082 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 53: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" OR1K1 "hg99, MNAB" ENSG00000165204 "Olfactory receptor family 1 subfamily K member 1" Q8NGR3 9 122800123-122801073 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" NA NA "Cluster 6: Non-specific - Immune response" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" OR1L1 "OR1L2, OR9-C" ENSG00000173679 "Olfactory receptor family 1 subfamily L member 1" Q8NH94 9 122661566-122662648 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 53: Neurons - Mixed function" OR1L3 OR9-D ENSG00000171481 "Olfactory receptor family 1 subfamily L member 3" Q8NH93 9 122675130-122676104 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA058878 Uncertain NA NA "Cluster 53: Neurons - Mixed function" "HPA058878: " OR1L4 "OR1L5, OR9-E" ENSG00000136939 "Olfactory receptor family 1 subfamily L member 4" Q8NGR5 9 122723990-122724925 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 6: Non-specific - Immune response" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" OR1L6 OR1L7 ENSG00000171459 "Olfactory receptor family 1 subfamily L member 6" Q8NGR2 9 122742303-122750783 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Epicardial cells: 4.5;Hematopoietic stem cells: 1.9;Retinal amacrine cells: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 6: Non-specific - Immune response" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" OR1L8 ENSG00000171496 "Olfactory receptor family 1 subfamily L member 8" Q8NGR8 9 122567117-122583384 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Early spermatids: 2.3;Epicardial cells: 2.3;Hematopoietic stem cells: 3.9;Late spermatids: 3.2;Mast cells: 6.6;Platelets: 2.8;Renal collecting duct intercalated cells: 2.4;Respiratory ionocytes: 2.5;Rod photoreceptor cells: 6.3" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in single" 8 "Kidney Chromophobe (TCGA): 3.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids" "Not detected" "Not detected" NA NA "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 58: Mast cells - Allergic inflammatory responses" "unprognostic (1.18e-1)" "unprognostic (2.14e-1)" OR1M1 OR19-6 ENSG00000170929 "Olfactory receptor family 1 subfamily M member 1" Q8NGA1 19 9087061-9095669 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Early primary spermatocytes: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 6: Non-specific - Immune response" "Cluster 56: Non-specific - Sensory perception" "Cluster 3: Early primary spermatocytes - Early meiosis" 1 "unprognostic (2.56e-2)" "unprognostic (2.72e-3)" OR1N1 "OR1-26, OR1N3" ENSG00000171505 "Olfactory receptor family 1 subfamily N member 1" Q8NGS0 9 122526358-122527296 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Ovary Serous Cystadenocarcinoma (TCGA): 1.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 53: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" "unprognostic (3.84e-2)" OR1N2 ENSG00000171501 "Olfactory receptor family 1 subfamily N member 2" Q8NGR9 9 122553112-122555173 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR1P1 "OR17-208, OR1P1P" ENSG00000262085 "Olfactory receptor family 1 subfamily P member 1 (gene/pseudogene)" 17 3153889-3154882 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 53: Squamous epithelial cells - Keratinization" OR1Q1 "HSTPCR106, OR1Q2, OR1Q3, OR9-A, OST226, OST226OR9-A, TPCR106" ENSG00000165202 "Olfactory receptor family 1 subfamily Q member 1" Q15612 9 122614738-122615682 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "retina: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA044828 Uncertain NA NA "Cluster 42: Retina - Visual perception" "Cluster 53: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "HPA044828: " OR1R1P "OR17-1, OR1R2P, OR1R3P, OR20A1P" ENSG00000180042 "Olfactory receptor family 1 subfamily R member 1 pseudogene" 17 3385930-3386874 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 11 "testis: 1.1" "Group enriched" "Detected in some" 4 "Early primary spermatocytes: 4.0;Early spermatids: 7.4;Epididymal principal cells: 3.9;Late primary spermatocytes: 8.1;Late spermatids: 3.2;Undifferentiated spermatogonia: 2.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 20 "plasmacytoid DC: 1.9" "Lineage enriched" "Detected in single" 20 "dendritic cells: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 79: Testis - Spermatogenesis" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" OR1S1 OST034 ENSG00000280204 "Olfactory receptor family 1 subfamily S member 1" 11 58212720-58216084 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 15: Kidney cancer - Membrane components" OR1S2 ENSG00000197887 "Olfactory receptor family 1 subfamily S member 2" 11 58203204-58204142 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR2A1 ENSG00000221970 "Olfactory receptor family 2 subfamily A member 1" Q8NGT9 7 144312419-144322737 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Tissue enhanced" "Detected in single" "thyroid gland: 1.1" "Cell type enriched" "Detected in single" 7 "Adipocytes: 4.4" "Cell type enhanced" "Detected in some" "endothelial cell: 1.4;fibroblast: 1.1;pericyte: 1.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA058272 Uncertain NA NA "Cluster 64: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 69: Skin cancer - ECM organization" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "HPA058272: " "unprognostic (6.00e-2)" OR2A12 OR2A12P ENSG00000221858 "Olfactory receptor family 2 subfamily A member 12" Q8NGT7 7 144086278-144098953 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 48: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" OR2A14 "OR2A14P, OR2A6, OST182" ENSG00000221938 "Olfactory receptor family 2 subfamily A member 14" Q96R47 7 144123176-144131188 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" OR2A2 "OR2A17P, OR2A2P, OST008" ENSG00000221989 "Olfactory receptor family 2 subfamily A member 2" Q6IF42 7 144109583-144110539 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR2A25 "OR2A25P, OR2A27" ENSG00000221933 "Olfactory receptor family 2 subfamily A member 25" A4D2G3 7 144069811-144075870 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA058272 Uncertain NA NA "Cluster 98: Neurons - Neurotransmission & signaling" "HPA058272: " OR2A4 OR2A10 ENSG00000180658 "Olfactory receptor family 2 subfamily A member 4" O95047 6 131699644-131701401 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "Kidney Renal Clear Cell Carcinoma (TCGA): 3.4" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 4 "basophil: 11.9" "Lineage enriched" "Detected in many" 4 "granulocytes: 11.9" "Not detected" "Not detected" HPA058272 Uncertain NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 58: Mast cells - Allergic inflammatory responses" 2 "HPA058272: " "unprognostic (5.38e-2)" "unprognostic (9.97e-3)" "unprognostic (3.57e-2)" OR2A42 ENSG00000212807 "Olfactory receptor family 2 subfamily A member 42" Q8NGT9 7 144228244-144239605 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Tissue enhanced" "Detected in single" "thyroid gland: 1.3" "Cell type enhanced" "Detected in single" "Renal collecting duct principal cells: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Spleen - B-cells (Spleen)" HPA058272 Uncertain NA NA "Cluster 58: Skin - Keratinization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 69: Skin cancer - ECM organization" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" "HPA058272: " OR2A5 "OR2A26, OR2A8, OR7-138, OR7-141" ENSG00000221836 "Olfactory receptor family 2 subfamily A member 5" Q96R48 7 144048948-144058845 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 9: Non-specific - Receptor signaling" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" OR2A7 HSDJ0798C17 ENSG00000243896 "Olfactory receptor family 2 subfamily A member 7" Q96R45 7 144257663-144264792 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "basophil: 12.2" "Lineage enriched" "Detected in many" 6 "granulocytes: 12.2" "Low cancer specificity" "Detected in many" HPA058272 Uncertain NA NA "Cluster 32: Basophils - Transcription" "Cluster 77: Intestine - Digestion" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "HPA058272: " "unprognostic (4.33e-2)" "unprognostic (1.56e-1)" "unprognostic (1.21e-1)" "unprognostic (2.06e-2)" "unprognostic (1.69e-2)" "unprognostic (3.54e-2)" "unprognostic (7.89e-2)" "unprognostic (1.08e-1)" "unprognostic (3.63e-2)" "unprognostic (4.95e-3)" "unprognostic (9.95e-2)" "unprognostic (3.82e-1)" "unprognostic (2.07e-3)" "unprognostic (1.49e-1)" "unprognostic (1.84e-1)" "unprognostic (6.20e-1)" "unprognostic (1.50e-1)" "unprognostic (6.61e-3)" "unprognostic (3.96e-1)" "unprognostic (3.04e-1)" "unprognostic (1.81e-1)" "unprognostic (1.24e-1)" "unprognostic (1.92e-1)" "unprognostic (1.02e-1)" "unprognostic (3.67e-1)" "unprognostic (1.36e-1)" OR2AE1 OR2AE2 ENSG00000244623 "Olfactory receptor family 2 subfamily AE member 1" Q8NHA4 7 99876062-99877033 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA042957 Uncertain NA NA "Cluster 34: Ciliated cells - Cilia assembly & function" "HPA042957: " "unprognostic (2.97e-1)" OR2AG1 OR2AG3 ENSG00000279486 "Olfactory receptor family 2 subfamily AG member 1" Q9H205 11 6783020-6791558 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 4.1;Hematopoietic stem cells: 2.4" "Low cell type specificity" "Detected in some" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 9: Non-specific - Receptor signaling" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 1 OR2AG2 OR2AG2P ENSG00000188124 "Olfactory receptor family 2 subfamily AG member 2" A6NM03 11 6765626-6771976 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 3.0;Brain inhibitory neurons: 4.9;Cone photoreceptor cells: 8.3;Early primary spermatocytes: 2.6;Ependymal cells: 2.1;Hematopoietic stem cells: 1.9;Megakaryocyte-Erythroid progenitors: 2.2;Other brain neurons: 3.2;Plasma cells: 3.2;Retinal amacrine cells: 2.1;Undifferentiated spermatogonia: 1.9" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 32: Cerebral cortex - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 35: Neurons - Synaptic function & neurogenesis" OR2AJ1 "OR2AJ1P, OR2AJ1Q" ENSG00000177275 "Olfactory receptor family 2 subfamily AJ member 1" Q8NGZ0 1 247924889-247935339 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Brain inhibitory neurons: 1.2;Cone photoreceptor cells: 4.1;Hematopoietic stem cells: 2.4;Megakaryocyte-Erythroid progenitors: 2.4;Megakaryocytes: 6.2;Other brain neurons: 1.1;Parietal cells: 1.8" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 109: Neurons - Neuronal signaling" OR2AK2 OR2AK1P ENSG00000187080 "Olfactory receptor family 2 subfamily AK member 2" 1 247965233-247966386 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Late spermatids: 2.0;Oligodendrocytes: 1.1" "Low cell type specificity" "Detected in some" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" NA NA "Cluster 9: Non-specific - Receptor signaling" "Cluster 109: Neurons - Neuronal signaling" OR2AP1 OR2AP1P ENSG00000179615 "Olfactory receptor family 2 subfamily AP member 1" Q8NGE2 12 55572468-55575612 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 14 "Cardiomyocytes: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 9: Non-specific - Receptor signaling" "Cluster 47: Leukemia - Hemostasis" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" OR2AT4 ENSG00000171561 "Olfactory receptor family 2 subfamily AT member 4" A6NND4 11 75081753-75096876 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 1.3;retina: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 40: Non-specific - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 56: Non-specific - Sensory perception" "unprognostic (3.36e-2)" "unprognostic (7.41e-2)" "unprognostic (1.81e-1)" OR2B11 ENSG00000177535 "Olfactory receptor family 2 subfamily B member 11" Q5JQS5 1 247449118-247458105 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "cDC: 1.6;Macrophages: 1.5;monocytes: 3.1;Neutrophils: 3.9;Thymocytes: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Neutrophils" "Not detected" "Not detected" "Not detected" "Not detected" HPA047459 Uncertain NA NA "Cluster 6: Non-specific - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" "HPA047459: " OR2B2 "hs6M1-10, OR2B2Q, OR2B9, OR6-1" ENSG00000168131 "Olfactory receptor family 2 subfamily B member 2" Q9GZK3 6 27911185-27912396 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" OR2B3 "OR2B3P, OR6-4" ENSG00000204703 "Olfactory receptor family 2 subfamily B member 3" O76000 6 29086208-29087313 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR2B6 "dJ408B20.2, OR2B1, OR2B1P, OR2B5, OR2B6P, OR5-40, OR5-41, OR6-31" ENSG00000124657 "Olfactory receptor family 2 subfamily B member 6" P58173 6 27957241-27958182 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 48 "Platelets: 76.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 2.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 47: Platelets - Hemostasis" "unprognostic (2.85e-1)" "unprognostic (4.33e-3)" "unprognostic (3.12e-2)" "unprognostic (7.68e-2)" "unprognostic (4.59e-1)" OR2B8P "hs6M1-29P, OR2B8" ENSG00000182477 "Olfactory receptor family 2 subfamily B member 8 pseudogene" 6 28053228-28054165 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 51: Neurons - Mixed function" "Cluster 6: Leukemia - Signal transduction" OR2C1 "OLFmf3, OR2C2P" ENSG00000168158 "Olfactory receptor family 2 subfamily C member 1" O95371 16 3355889-3357306 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "unprognostic (1.47e-2)" OR2C3 "OR2C4, OR2C5P, OST742" ENSG00000196242 "Olfactory receptor family 2 subfamily C member 3" Q8N628 1 247524677-247536440 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Adipocytes: 1.8;Early primary spermatocytes: 7.6;Early spermatids: 3.2;Fibro-adipogenic progenitors: 1.7;Kupffer cells: 2.0;Late primary spermatocytes: 8.5;Late spermatids: 6.5;Mast cells: 4.8;pDCs: 2.1;Prostatic glandular cells: 1.9;Sertoli cells: 3.6;Undifferentiated spermatogonia: 3.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "basophil: 1.9" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.9" "Not detected" "Not detected" "Prostate - Prostate glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" HPA058578 Supported "Plasma membrane" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 66: Non-specific - Mitochondria" "Cluster 3: Early primary spermatocytes - Early meiosis" "Plasma membrane" "HPA058578: " OR2D2 "hg27, OR11-610, OR2D1" ENSG00000166368 "Olfactory receptor family 2 subfamily D member 2" Q9H210 11 6891574-6892500 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 32: Cerebral cortex - Mixed function" "Cluster 54: Non-specific - Transcription" OR2D3 ENSG00000178358 "Olfactory receptor family 2 subfamily D member 3" Q8NGH3 11 6921002-6921994 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Epicardial cells: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA052551 Uncertain NA NA "Cluster 32: Cerebral cortex - Mixed function" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" "HPA052551: " OR2F1 "OLF3, OR14-60, OR2F3, OR2F3P, OR2F4, OR2F5, OR7-139, OR7-140" ENSG00000213215 "Olfactory receptor family 2 subfamily F member 1" Q13607 7 143954844-143997312 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Cytotrophoblasts: 3.5;Early spermatids: 1.9;Late primary spermatocytes: 2.0;Late spermatids: 2.1;Syncytiotrophoblasts: 5.9" "Cell type enhanced" "Detected in single" "pericyte: 2.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" NA NA "Cluster 63: Cytotrophoblasts - Basic cellular functions" OR2F2 OR7-1 ENSG00000221910 "Olfactory receptor family 2 subfamily F member 2" O95006 7 143935233-143936186 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR2G2 ENSG00000177489 "Olfactory receptor family 2 subfamily G member 2" Q8NGZ5 1 247588360-247589313 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR2G3 ENSG00000177476 "Olfactory receptor family 2 subfamily G member 3" Q8NGZ4 1 247605586-247606515 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR2G6 ENSG00000188558 "Olfactory receptor family 2 subfamily G member 6" Q5TZ20 1 248508073-248527337 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 15 "Proximal tubule cells: 37.2" "Cell type enhanced" "Detected in some" "upper-layer intratelencephalic: 2.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Late spermatids" NA NA "Cluster 9: Non-specific - Receptor signaling" "Cluster 55: Lymphoma - Immune response" "Cluster 88: Proximal tubular cells - Transmembrane transport" 1 "unprognostic (1.04e-1)" "unprognostic (3.36e-2)" OR2H1 "OR2H6, OR2H8, OR6-2" ENSG00000204688 "Olfactory receptor family 2 subfamily H member 1" Q9GZK4 6 29457155-29464328 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 119 "testis: 11.8" "Group enriched" "Detected in some" 19 "Early spermatids: 8.9;Ependymal cells: 5.1;Late primary spermatocytes: 5.3;Late spermatids: 3.6" "Cell type enriched" "Detected in some" 4 "ependymal cell: 5.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" OR2H2 hs6M1-12 ENSG00000204657 "Olfactory receptor family 2 subfamily H member 2" O95918 6 29585121-29590500 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 2.2;epididymis: 4.5;testis: 2.3" "Cell type enhanced" "Detected in some" "Astrocytes: 3.3;Bergmann glia: 6.7;Brain excitatory neurons: 1.8;Brain inhibitory neurons: 4.3;Other brain neurons: 1.1" "Cell type enhanced" "Detected in many" "Bergmann glia: 11.7;medium spiny neuron: 9.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 33: Neurons - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 35: Neurons - Synaptic function & neurogenesis" OR2I1P "HS6M1-14, OR2I1, OR2I2, OR2I3P, OR2I4P" ENSG00000237988 "Olfactory receptor family 2 subfamily I member 1 pseudogene" 6 29550407-29557773 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 14 "basophil: 1.3" "Lineage enriched" "Detected in single" 14 "granulocytes: 1.3" "Not detected" "Not detected" "Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Ductal cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 109: Neurons - Neuronal signaling" "unprognostic (4.24e-2)" "unprognostic (6.83e-2)" OR2J1 "dJ80I19.2, hs6M1-4, OR2J1P, OR6-5" ENSG00000204702 "Olfactory receptor family 2 subfamily J member 1" Q9GZK6 6 29099490-29102701 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR2J2 "dJ80I19.4, hs6M1-6, OR6-8" ENSG00000204700 "Olfactory receptor family 2 subfamily J member 2" O76002 6 29170907-29175811 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 146 "Ependymal cells: 42.6" "Cell type enriched" "Detected in some" 38 "ependymal cell: 45.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" NA NA "Cluster 46: Brainstem - Mixed function" "Cluster 34: Ciliated cells - Cilia assembly & function" OR2J3 OR6-6 ENSG00000204701 "Olfactory receptor family 2 subfamily J member 3" O76001 6 29108058-29114770 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "Early spermatids: 4.1;Late primary spermatocytes: 5.9;Late spermatids: 2.9" "Cell type enriched" "Detected in single" 6 "midbrain-derived inhibitory: 1.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" NA NA "Cluster 46: Brainstem - Mixed function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" OR2K2 "HSHTPCRH06, HTPCRH06, OR2AR1P" ENSG00000171133 "Olfactory receptor family 2 subfamily K member 2" Q8NGT1 9 111327229-111330224 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA024261 Uncertain NA NA "Cluster 51: Myeloma - Immunoglobulins" "Cluster 82: Dendritic cells - Antigen presentation" "HPA024261: " OR2L13 OR2L14 ENSG00000196071 "Olfactory receptor family 2 subfamily L member 13" Q8N349 1 248095184-248101163 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 7 "brain: 5.7;retina: 2.0" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 2.9;Brain inhibitory neurons: 3.4;Cone photoreceptor cells: 2.1;Early spermatids: 2.2;Hematopoietic stem cells: 4.4;Late primary spermatocytes: 4.1;Oligodendrocyte progenitor cells: 2.5;Oligodendrocytes: 6.3;Other brain neurons: 3.7;Retinal bipolar cells: 1.4;Retinal ganglion cells: 3.9;Retinal horizontal cells: 2.0" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 109: Neurons - Neuronal signaling" "unprognostic (2.59e-3)" OR2L2 "HSHTPCRH07, HTPCRH07, OR2L12, OR2L4P" ENSG00000203663 "Olfactory receptor family 2 subfamily L member 2" Q8NH16 1 248030070-248042305 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 1.2;retina: 1.5" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 7.2;Brain inhibitory neurons: 7.3;Early spermatids: 5.5;Gonadotrophs: 3.6;Hematopoietic stem cells: 7.3;Late primary spermatocytes: 5.0;Late spermatids: 7.4;Megakaryocyte-Erythroid progenitors: 3.9;Oligodendrocyte progenitor cells: 5.5;Oligodendrocytes: 11.3;Other brain neurons: 7.1;Retinal ganglion cells: 7.7;Sertoli cells: 3.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 9: Non-specific - Receptor signaling" "Cluster 56: Non-specific - Sensory perception" "Cluster 109: Neurons - Neuronal signaling" "unprognostic (1.83e-2)" "unprognostic (1.67e-3)" "unprognostic (4.71e-2)" OR2L3 ENSG00000198128 "Olfactory receptor family 2 subfamily L member 3" Q8NG85 1 248046836-248063407 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 12.3;Brain inhibitory neurons: 12.4;Gonadotrophs: 5.7;Hematopoietic stem cells: 15.5;Oligodendrocyte progenitor cells: 9.7;Oligodendrocytes: 16.4;Other brain neurons: 12.7;Retinal bipolar cells: 5.7;Retinal ganglion cells: 27.0" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 9: Non-specific - Receptor signaling" "Cluster 109: Neurons - Neuronal signaling" OR2L5 "OR2L11, OR2L5P" ENSG00000197454 "Olfactory receptor family 2 subfamily L member 5" Q8NG80 1 248013660-248024276 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 8.7;Brain inhibitory neurons: 8.9;Gonadotrophs: 4.0;Hematopoietic stem cells: 8.7;Oligodendrocyte progenitor cells: 6.2;Oligodendrocytes: 12.8;Other brain neurons: 8.7;Retinal ganglion cells: 3.9;Thymocytes: 2.5" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 9: Non-specific - Receptor signaling" "Cluster 109: Neurons - Neuronal signaling" OR2L8 ENSG00000279263 "Olfactory receptor family 2 subfamily L member 8" Q8NGY9 1 247948858-247949796 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Low cell type specificity" "Detected in single" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 9: Non-specific - Receptor signaling" "Cluster 109: Neurons - Neuronal signaling" OR2M2 "OR2M2Q, OST423" ENSG00000198601 "Olfactory receptor family 2 subfamily M member 2" Q96R28 1 248174821-248181067 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 1.3;Brain inhibitory neurons: 1.4;Other brain neurons: 1.6;Retinal ganglion cells: 3.9" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 24: Neurons - Mixed function" "Cluster 109: Neurons - Neuronal signaling" OR2M3 "OR2M3P, OR2M6, OST003" ENSG00000228198 "Olfactory receptor family 2 subfamily M member 3" Q8NG83 1 248197265-248212925 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "retina: 3.4" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 3.4;Brain inhibitory neurons: 3.4;Fallopian tube ciliated cells: 2.1;Hematopoietic stem cells: 1.5;Oligodendrocyte progenitor cells: 1.2;Oligodendrocytes: 2.0;Other brain neurons: 4.0;Retinal bipolar cells: 1.9;Retinal ganglion cells: 3.9" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Stomach Adenocarcinoma (TCGA): 3.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" NA NA "Cluster 40: Non-specific - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 109: Neurons - Neuronal signaling" "unprognostic (7.64e-3)" "unprognostic (7.36e-2)" "unprognostic (1.39e-1)" "unprognostic (1.64e-2)" "unprognostic (2.94e-2)" "unprognostic (3.52e-2)" "unprognostic (8.21e-2)" "unprognostic (1.67e-2)" "unprognostic (6.00e-2)" "unprognostic (5.20e-1)" OR2M4 "HSHTPCRX18, HTPCRX18, OST710, TPCR100" ENSG00000171180 "Olfactory receptor family 2 subfamily M member 4" Q96R27 1 248231417-248244679 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 5.1;Brain inhibitory neurons: 5.3;Fallopian tube ciliated cells: 3.1;Hematopoietic stem cells: 1.9;Oligodendrocyte progenitor cells: 1.9;Oligodendrocytes: 3.4;Other brain neurons: 6.2;Platelets: 1.4;Retinal amacrine cells: 2.8;Retinal bipolar cells: 3.6;Retinal ganglion cells: 11.6;Thymocytes: 1.7" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA051308 Uncertain NA NA "Cluster 9: Non-specific - Receptor signaling" "Cluster 56: Non-specific - Sensory perception" "Cluster 109: Neurons - Neuronal signaling" "HPA051308: " "unprognostic (1.18e-1)" "potential prognostic favorable (5.97e-4)" OR2M5 OR2M5P ENSG00000162727 "Olfactory receptor family 2 subfamily M member 5" A3KFT3 1 248145148-248146086 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 24: Neurons - Mixed function" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" OR2M7 ENSG00000177186 "Olfactory receptor family 2 subfamily M member 7" Q8NG81 1 248323630-248324568 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 65: Non-specific - Unknown function" OR2S2 ENSG00000278889 "Olfactory receptor family 2 subfamily S member 2" Q9NQN1 9 35957108-35958154 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 64: Connective tissue cells - ECM organization" OR2T1 OR1-25 ENSG00000175143 "Olfactory receptor family 2 subfamily T member 1" 1 248403048-248408020 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR2T10 ENSG00000184022 "Olfactory receptor family 2 subfamily T member 10" Q8NGZ9 1 248590487-248597700 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 23 "kidney: 4.6" "Cell type enriched" "Detected in some" 9 "Proximal tubule cells: 26.0" "Cell type enhanced" "Detected in some" "amygdala excitatory: 1.6;deep-layer intratelencephalic: 1.6;miscellaneous: 1.6;upper-layer intratelencephalic: 2.6" "Cancer enhanced" "Detected in single" "Kidney Renal Clear Cell Carcinoma (TCGA): 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA052019 Uncertain NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 55: Lymphoma - Immune response" "Cluster 88: Proximal tubular cells - Transmembrane transport" "HPA052019: " "potential prognostic favorable (2.75e-5)" "unprognostic (3.14e-3)" OR2T11 OR2T11Q ENSG00000279301 "Olfactory receptor family 2 subfamily T member 11" Q8NH01 1 248623557-248635091 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 32 "Proximal tubule cells: 68.1" "Cell type enhanced" "Detected in some" "amygdala excitatory: 2.1;deep-layer intratelencephalic: 2.1;upper-layer intratelencephalic: 3.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 88: Proximal tubular cells - Transmembrane transport" OR2T12 ENSG00000177201 "Olfactory receptor family 2 subfamily T member 12" Q8NG77 1 248290139-248303424 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Oocytes: 4.6;Podocytes: 1.3;Proximal tubule cells: 1.3;Retinal amacrine cells: 2.1;Retinal bipolar cells: 2.7;Retinal ganglion cells: 7.7" "Cell type enhanced" "Detected in some" "lower rhombic lip: 1.4;mammillary body: 1.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 9: Non-specific - Receptor signaling" "Cluster 56: Non-specific - Sensory perception" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "unprognostic (4.72e-2)" "unprognostic (5.09e-3)" OR2T2 OR2T2P ENSG00000196240 "Olfactory receptor family 2 subfamily T member 2" Q6IF00 1 248445512-248455725 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 22 "Proximal tubule cells: 11.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 55: Lymphoma - Immune response" "Cluster 88: Proximal tubular cells - Transmembrane transport" OR2T27 ENSG00000187701 "Olfactory receptor family 2 subfamily T member 27" Q8NH04 1 248649838-248655528 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" OR2T29 ENSG00000182783 "Olfactory receptor family 2 subfamily T member 29" Q8NH02 1 248556912-248562772 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 7 "Proximal tubule cells: 3.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 55: Lymphoma - Immune response" "Cluster 88: Proximal tubular cells - Transmembrane transport" OR2T3 ENSG00000196539 "Olfactory receptor family 2 subfamily T member 3" Q8NH03 1 248473351-248474307 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Minor Salivary Gland - Minor salivary glandular cells" NA NA OR2T33 ENSG00000177212 "Olfactory receptor family 2 subfamily T member 33" Q8NG76 1 248269917-248277976 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 9: Non-specific - Receptor signaling" "Cluster 50: Lymphoma - Unknown function" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" OR2T34 ENSG00000183310 "Olfactory receptor family 2 subfamily T member 34" Q8NGX1 1 248573801-248574757 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 54: Non-specific - Transcription" "Cluster 102: Non-specific - Mixed function" OR2T35 ENSG00000177151 "Olfactory receptor family 2 subfamily T member 35" Q8NGX2 1 248636356-248645278 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "Oocytes: 4.6;Proximal tubule cells: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 88: Proximal tubular cells - Transmembrane transport" OR2T4 OR2T4Q ENSG00000196944 "Olfactory receptor family 2 subfamily T member 4" 1 248361665-248362627 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR2T5 ENSG00000203661 "Olfactory receptor family 2 subfamily T member 5" Q6IEZ7 1 248488589-248491113 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 54: Non-specific - Transcription" OR2T6 "OR2T6P, OR2T9, OST703" ENSG00000198104 "Olfactory receptor family 2 subfamily T member 6" Q8NHC8 1 248375746-248391811 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 4 "Podocytes: 5.7" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 9: Non-specific - Receptor signaling" "Cluster 109: Neurons - Neuronal signaling" OR2T7 "OR2T7P, OST723" ENSG00000227152 "Olfactory receptor family 2 subfamily T member 7" 1 248436359-248444316 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 32: Cerebral cortex - Mixed function" OR2T8 OR2T8P ENSG00000177462 "Olfactory receptor family 2 subfamily T member 8" A6NH00 1 247920252-247923152 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "thyroid gland: 1.0" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 1.7;Differentiating spermatogonia: 2.6;Erythrocyte progenitors: 1.6;Late primary spermatocytes: 2.1;Megakaryocyte progenitors: 2.7;Megakaryocyte-Erythroid progenitors: 2.8;Megakaryocytes: 12.4;Migrating cytotrophoblasts: 1.8;Retinal ganglion cells: 3.9;Thymocytes: 2.5" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Adrenocortical cancer: 1.9;liver cancer: 1.0" "Prostate - Prostate glandular cells" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 47: Platelets - Hemostasis" OR2V1 "OR2V1P, OST265" ENSG00000185372 "Olfactory receptor family 2 subfamily V member 1" Q8NHB1 5 181123122-181131169 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "liver: 2.0;retina: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA049953 Uncertain NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 9: Non-specific - Receptor signaling" "Cluster 55: Lymphoma - Immune response" "Cluster 35: Neurons - Synaptic function & neurogenesis" "HPA049953: " "unprognostic (3.25e-2)" "unprognostic (2.34e-1)" OR2V2 "OR2V3, OST713" ENSG00000182613 "Olfactory receptor family 2 subfamily V member 2" Q96R30 5 181147586-181159285 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Medullary thymic epithelial cells: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA049953 Uncertain NA NA "Cluster 11: White matter - Signal transduction" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 9: T-cells - Adaptive immunity: Regulation" "HPA049953: " "unprognostic (4.05e-2)" OR2W1 hs6M1-15 ENSG00000204704 "Olfactory receptor family 2 subfamily W member 1" Q9Y3N9 6 29044213-29045175 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR2W3 "OR2W3P, OR2W8P, OST718" ENSG00000238243 "Olfactory receptor family 2 subfamily W member 3" Q7Z3T1 1 247895587-247896531 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "bone marrow: 12.2;thyroid gland: 5.9" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Thyroid Carcinoma (TCGA): 4.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "thyroid cancer: 8.6" "Spleen - Erythrocytes, Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA045594 Uncertain NA NA "Cluster 15: Bone marrow - Innate immune response" "Cluster 1: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" "HPA045594: " "unprognostic (1.15e-1)" "unprognostic (1.11e-1)" "unprognostic (2.70e-2)" OR2Y1 ENSG00000174339 "Olfactory receptor family 2 subfamily Y member 1" Q8NGV0 5 180739123-180740058 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 60: Prostate cancer - Unknown function" OR2Z1 OR2Z2 ENSG00000181733 "Olfactory receptor family 2 subfamily Z member 1" Q8NG97 19 8721634-8732160 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 4 "Gastric progenitor cells: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA048760 Uncertain NA NA "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" "HPA048760: " OR3A1 "OLFRA03, OR17-40, OR40" ENSG00000180090 "Olfactory receptor family 3 subfamily A member 1" P47881 17 3291017-3298360 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 38: Sub-cortical - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" 1 OR3A2 "OLFRA04, OR17-228, OR228" ENSG00000221882 "Olfactory receptor family 3 subfamily A member 2" 17 3276177-3386317 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "testis: 2.7" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 29.8;Early primary spermatocytes: 63.8;Early spermatids: 18.3;Lactotrophs: 22.1;Microglia: 51.8;Pituicytes/FSCs: 41.4;Rod photoreceptor cells: 21.7;Sertoli cells: 41.7;Somatotrophs: 19.5;Undifferentiated spermatogonia: 44.6" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 55.8" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 2.2" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in single" "Rhabdoid: 2.1" "Low region specificity" "Detected in single" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 67: Testis - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" "unprognostic (1.40e-1)" "unprognostic (3.87e-3)" OR3A3 "OR17-137, OR17-16, OR17-201, OR3A6, OR3A7, OR3A8P" ENSG00000159961 "Olfactory receptor family 3 subfamily A member 3" 17 3411370-3424070 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 4.9;Epicardial cells: 2.3;Medullary thymic epithelial cells: 2.4;Mucous neck cells: 1.2;Myonuclei: 1.5;pDCs: 3.1;Retinal horizontal cells: 2.0;Sertoli cells: 1.1" "Low cell type specificity" "Detected in some" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 25 "plasmacytoid DC: 8.0" "Lineage enriched" "Detected in single" 25 "dendritic cells: 8.0" "Not detected" "Not detected" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 37: Neurons - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" OR4A15 ENSG00000181958 "Olfactory receptor family 4 subfamily A member 15" 11 55367974-55368918 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR4A16 OR4A16Q ENSG00000181961 "Olfactory receptor family 4 subfamily A member 16" Q8NH70 11 55343201-55344187 "Cancer-related genes, G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 32: Non-specific - Cell proliferation" OR4A47 ENSG00000237388 "Olfactory receptor family 4 subfamily A member 47" Q6IF82 11 48488793-48489722 "Essential proteins, G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA059763 Uncertain NA NA "HPA059763: " OR4A5 ENSG00000221840 "Olfactory receptor family 4 subfamily A member 5" Q8NH83 11 54706832-54707902 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR4A8 OR4A8P ENSG00000225997 "Olfactory receptor family 4 subfamily A member 8 (gene/pseudogene)" 11 54682877-54683821 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR4B1 OST208 ENSG00000175619 "Olfactory receptor family 4 subfamily B member 1" Q8NGF8 11 48216810-48217739 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA059443 Uncertain NA NA "HPA059443: " OR4C11 OR4C11P ENSG00000172188 "Olfactory receptor family 4 subfamily C member 11" Q6IEV9 11 55602360-55607645 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR4C12 ENSG00000221954 "Olfactory receptor family 4 subfamily C member 12" Q96R67 11 49981473-49982535 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR4C13 ENSG00000258817 "Olfactory receptor family 4 subfamily C member 13" Q8NGP0 11 49952391-49953419 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR4C15 ENSG00000181939 "Olfactory receptor family 4 subfamily C member 15" Q8NGM1 11 55554307-55555419 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA061939 Uncertain NA NA "HPA061939: " OR4C16 ENSG00000279514 "Olfactory receptor family 4 subfamily C member 16" Q8NGL9 11 55572128-55573060 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 72: Neuronal - Signal transduction" OR4C3 ENSG00000176547 "Olfactory receptor family 4 subfamily C member 3" Q8NH37 11 48324920-48325955 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR4C45 ENSG00000260811 "Olfactory receptor family 4 subfamily C member 45 (gene/pseudogene)" 11 50032874-50033794 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR4C46 ENSG00000185926 "Olfactory receptor family 4 subfamily C member 46" A6NHA9 11 54603069-54603998 "Essential proteins, G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR4C5 "OR4C5P, OR4C5Q" ENSG00000176540 "Olfactory receptor family 4 subfamily C member 5" Q8NGB2 11 48365485-48366465 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA049516 Uncertain NA NA "HPA049516: " OR4C6 ENSG00000181903 "Olfactory receptor family 4 subfamily C member 6" Q8NH72 11 55662201-55666195 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Myeloma: 1.8" "Not detected" "Not detected" NA NA "Cluster 51: Myeloma - Immunoglobulins" "Cluster 44: Plasma cells - Antibody production & secretion" OR4D1 "OR4D3, TPCR16" ENSG00000141194 "Olfactory receptor family 4 subfamily D member 1" Q15615 17 58148384-58159585 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Early spermatids: 2.8;Hematopoietic stem cells: 2.4;Innate lymphoid cells: 3.6;Megakaryocyte progenitors: 5.0;Megakaryocyte-Erythroid progenitors: 4.3;Megakaryocytes: 6.2;NK-cells: 2.0;Platelets: 2.8;Retinal ganglion cells: 3.9;T-cells: 1.2" "Cell type enhanced" "Detected in some" "leukocyte: 1.3;lower rhombic lip: 3.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 6: Non-specific - Immune response" "Cluster 56: Non-specific - Sensory perception" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" OR4D10 "OR4D10P, OST711" ENSG00000254466 "Olfactory receptor family 4 subfamily D member 10" Q8NGI6 11 59473315-59479361 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Early spermatids: 2.0;Late spermatids: 1.5;Lymphatic endothelial cells: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" OR4D11 OR4D11P ENSG00000176200 "Olfactory receptor family 4 subfamily D member 11" Q8NGI4 11 59503576-59504511 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR4D2 ENSG00000255713 "Olfactory receptor family 4 subfamily D member 2" P58180 17 58166982-58171411 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 3: Early primary spermatocytes - Early meiosis" OR4D5 ENSG00000171014 "Olfactory receptor family 4 subfamily D member 5" Q8NGN0 11 123939617-123940573 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045005 Uncertain NA NA "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "HPA045005: " OR4D6 ENSG00000166884 "Olfactory receptor family 4 subfamily D member 6" Q8NGJ1 11 59456961-59457905 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 53: Squamous epithelial cells - Keratinization" OR4D9 ENSG00000172742 "Olfactory receptor family 4 subfamily D member 9" Q8NGE8 11 59511368-59520703 "Essential proteins, G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 6 "Retinal ganglion cells: 3.9" "Cell type enhanced" "Detected in some" "endothelial cell: 1.7;vascular associated smooth muscle cell: 1.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 48: Non-specific - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 104: Brain endothelial cells - Blood brain barrier" "unprognostic (1.87e-1)" "unprognostic (1.31e-2)" OR4E1 OR4E1P ENSG00000276240 "Olfactory receptor family 4 subfamily E member 1" P0C645 14 21667886-21673818 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" OR4E2 ENSG00000221977 "Olfactory receptor family 4 subfamily E member 2" 14 21653835-21667642 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "Cholangiocytes: 2.0;Early spermatids: 3.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 12 "Bone cancer: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" OR4F15 ENSG00000182854 "Olfactory receptor family 4 subfamily F member 15" Q8NGB8 15 101812202-101820197 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Proximal tubule cells: 1.5;Schwann cells: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 48: Non-specific - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 88: Proximal tubular cells - Transmembrane transport" OR4F16 ENSG00000284662 "Olfactory receptor family 4 subfamily F member 16" Q6IEY1 1 685716-686654 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047705 Uncertain NA NA 1 "HPA047705: " OR4F17 "OR4F11P, OR4F18, OR4F19" ENSG00000176695 "Olfactory receptor family 4 subfamily F member 17" Q8NGA8 19 107104-117102 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 51: Myeloma - Immunoglobulins" OR4F21 OR4F21P ENSG00000176269 "Olfactory receptor family 4 subfamily F member 21" O95013 8 166086-167024 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047705 Uncertain NA NA "Cluster 1: Neurons - Mixed function" "HPA047705: " OR4F29 ENSG00000284733 "Olfactory receptor family 4 subfamily F member 29" Q6IEY1 1 450740-451678 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047705 Uncertain NA NA 1 "HPA047705: " "unprognostic (1.46e-1)" OR4F3 ENSG00000230178 "Olfactory receptor family 4 subfamily F member 3" Q6IEY1 5 181367268-181368262 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047705 Uncertain NA NA "Cluster 9: Non-specific - Receptor signaling" "Cluster 51: Myeloma - Immunoglobulins" 1 "HPA047705: " OR4F4 OR4F18 ENSG00000177693 "Olfactory receptor family 4 subfamily F member 4" 15 101922042-101923113 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR4F5 ENSG00000186092 "Olfactory receptor family 4 subfamily F member 5" 1 65419-71585 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR4F6 OR4F12 ENSG00000184140 "Olfactory receptor family 4 subfamily F member 6" Q8NGB9 15 101803509-101806887 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 9: T-cells - Adaptive immunity: Regulation" OR4K1 ENSG00000155249 "Olfactory receptor family 4 subfamily K member 1" Q8NGD4 14 19930917-19936757 "Essential proteins, G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Late primary spermatocytes: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA028877 Uncertain NA NA "Cluster 47: Leukemia - Hemostasis" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" "HPA028877: " OR4K13 ENSG00000176253 "Olfactory receptor family 4 subfamily K member 13" Q8NH42 14 20029399-20036038 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 48: Non-specific - Mixed function" OR4K14 ENSG00000169484 "Olfactory receptor family 4 subfamily K member 14" Q8NGD5 14 20014143-20019307 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR4K15 OR4K15Q ENSG00000169488 "Olfactory receptor family 4 subfamily K member 15" Q8NH41 14 19975591-19976565 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA055732 Uncertain NA NA "HPA055732: " OR4K17 ENSG00000176230 "Olfactory receptor family 4 subfamily K member 17" Q8NGC6 14 20110739-20122199 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "bone marrow: 1.8;liver: 5.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 56: Non-specific - Sensory perception" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" "unprognostic (2.53e-1)" "unprognostic (2.98e-3)" "unprognostic (8.03e-2)" OR4K2 ENSG00000165762 "Olfactory receptor family 4 subfamily K member 2" Q8NGD2 14 19875142-19883932 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" OR4K3 OR4K3P ENSG00000176290 "Olfactory receptor family 4 subfamily K member 3 (gene/pseudogene)" 14 19868197-19869143 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR4K5 ENSG00000176281 "Olfactory receptor family 4 subfamily K member 5" Q8NGD3 14 19920607-19921578 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR4L1 OR4L2P ENSG00000176246 "Olfactory receptor family 4 subfamily L member 1" Q8NH43 14 20060045-20060983 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR4M1 ENSG00000176299 "Olfactory receptor family 4 subfamily M member 1" Q8NGD0 14 19773504-19783696 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "Early spermatids: 3.8;Late primary spermatocytes: 8.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA058889 Uncertain NA NA "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" "HPA058889: " OR4M2 ENSG00000274102 "Olfactory receptor family 4 subfamily M member 2" Q8NGB6 15 22070241-22083221 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Group enriched" "Detected in some" 83 "Early spermatids: 19.8;Late primary spermatocytes: 5.6;Late spermatids: 10.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA058889 Uncertain NA NA "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" "HPA058889: " OR4M2-OT1 ENSG00000285472 "OR4M2 overlapping transcript 1" 15 22015233-22095857 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 46 "testis: 4.6" "Cell type enhanced" "Detected in some" "Early spermatids: 9.3;Late primary spermatocytes: 2.7;Myosatellite cells: 2.3;Undifferentiated spermatogonia: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA057442 Uncertain Approved Centrosome NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" Centrosome "HPA057442: " OR4M2B ENSG00000182974 "Olfactory receptor family 4 subfamily M member 2B" A0A0X1KG70 15 21637909-21638992 "Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA058889 Uncertain NA NA "Cluster 51: Myeloma - Immunoglobulins" "HPA058889: " OR4N2 ENSG00000176294 "Olfactory receptor family 4 subfamily N member 2" Q8NGD1 14 19719015-19830253 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 6 "testis: 3.5" "Group enriched" "Detected in some" 9 "Early spermatids: 68.4;Late primary spermatocytes: 64.2" "Cell type enhanced" "Detected in single" "oligodendrocyte: 1.0" "Cancer enriched" "Detected in single" 8 "Glioblastoma Multiforme (TCGA): 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" "unprognostic (2.82e-2)" "potential prognostic favorable (5.21e-4)" OR4N4 ENSG00000183706 "Olfactory receptor family 4 subfamily N member 4" Q8N0Y3 15 22094522-22095862 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 58 "testis: 5.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA057442 Uncertain Uncertain Centrosome NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" Centrosome "HPA057442: " OR4N4C ENSG00000279408 "Olfactory receptor family 4 subfamily N member 4C" A0A096LPK9 15 21651844-21652968 "Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 23 "testis: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" HPA057442 Uncertain Uncertain Centrosome NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" Centrosome "HPA057442: " OR4N5 ENSG00000184394 "Olfactory receptor family 4 subfamily N member 5" Q8IXE1 14 20138820-20145471 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 47: Leukemia - Hemostasis" OR4P4 OR4P3P ENSG00000181927 "Olfactory receptor family 4 subfamily P member 4" Q8NGL7 11 55635113-55640309 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA059458 Uncertain NA NA "Cluster 9: Non-specific - Receptor signaling" "Cluster 110: Mural cells - ECM organization" "HPA059458: " OR4Q2 OR4Q2P ENSG00000196383 "Olfactory receptor family 4 subfamily Q member 2 (gene/pseudogene)" 14 19999913-20004760 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" OR4Q3 "C14orf13, OR4Q4" ENSG00000182652 "Olfactory receptor family 4 subfamily Q member 3" 14 19743571-19749469 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA049924 Uncertain NA NA "Cluster 51: Myeloma - Immunoglobulins" "HPA049924: " OR4S1 ENSG00000176555 "Olfactory receptor family 4 subfamily S member 1" Q8NGB4 11 48306223-48307152 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR4S2 "OR4S2P, OST725" ENSG00000174982 "Olfactory receptor family 4 subfamily S member 2" Q8NH73 11 55648327-55652854 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR4X1 ENSG00000176567 "Olfactory receptor family 4 subfamily X member 1" Q8NH49 11 48263861-48264778 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR4X2 ENSG00000172208 "Olfactory receptor family 4 subfamily X member 2" Q8NGF9 11 48245104-48246015 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR51A2 ENSG00000205496 "Olfactory receptor family 51 subfamily A member 2" Q8NGJ7 11 4954772-4955713 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR51A4 ENSG00000205497 "Olfactory receptor family 51 subfamily A member 4" Q8NGJ6 11 4942831-4947605 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" OR51A7 ENSG00000176895 "Olfactory receptor family 51 subfamily A member 7" Q8NH64 11 4903783-4909462 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA061356 Uncertain NA NA "HPA061356: " OR51B2 OR51B1P ENSG00000279012 "Olfactory receptor family 51 subfamily B member 2" Q9Y5P1 11 5323359-5324297 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 1: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" 1 OR51B4 ENSG00000183251 "Olfactory receptor family 51 subfamily B member 4" Q9Y5P0 11 5301014-5301946 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 1: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" OR51B5 ENSG00000167355 "Olfactory receptor family 51 subfamily B member 5" Q9H339 11 5303444-5505652 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "Late spermatids: 6.8;Oocytes: 23.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA063124 Uncertain NA NA "Cluster 51: Myeloma - Immunoglobulins" "Cluster 41: Oocytes - Oogenesis" "HPA063124: " OR51B6 ENSG00000176239 "Olfactory receptor family 51 subfamily B member 6" Q9H340 11 5351508-5352446 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 51: Myeloma - Immunoglobulins" OR51C1P "OR51C2P, OR51C3P, OST734" ENSG00000197674 "Olfactory receptor family 51 subfamily C member 1 pseudogene" 11 4690423-4697853 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 39 "Prostate Adenocarcinoma (TCGA): 3.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Prostate - Prostate glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 10: Ciliated cells - Ion channel activity" "unprognostic (2.38e-1)" OR51D1 OR51D1Q ENSG00000197428 "Olfactory receptor family 51 subfamily D member 1" Q8NGF3 11 4637477-4643060 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Gastric chief cells: 1.1;Prostatic glandular cells: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA061240 Uncertain NA NA "Cluster 11: White matter - Signal transduction" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" "HPA061240: " OR51E1 "GPR136, GPR164, OR51E1P, OR52A3P" ENSG00000180785 "Olfactory receptor family 51 subfamily E member 1" Q8TCB6 11 4643420-4655488 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 5.4;placenta: 7.0;prostate: 6.2" "Cell type enhanced" "Detected in some" "Neuroendocrine cells: 49.0;Pericytes: 7.6;Prostatic glandular cells: 130.3;Vascular smooth muscle cells: 26.7" "Cell type enriched" "Detected in single" 170 "vascular associated smooth muscle cell: 21.5" "Cancer enriched" "Detected in some" 13 "Prostate Adenocarcinoma (TCGA): 56.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "colorectal cancer: 1.8;lung cancer: 2.5;prostate cancer: 7.0;thyroid cancer: 2.0" "Prostate - Prostate glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB019995, HPA051439" Approved NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 1 "CAB019995: , HPA051439: " "unprognostic (2.71e-1)" "unprognostic (2.62e-2)" "unprognostic (8.66e-2)" "unprognostic (1.76e-2)" "unprognostic (8.27e-2)" "unprognostic (8.72e-3)" "unprognostic (1.80e-3)" "unprognostic (1.01e-1)" "unprognostic (1.27e-2)" "unprognostic (2.99e-1)" "unprognostic (1.48e-1)" OR51E2 PSGR ENSG00000167332 "Olfactory receptor family 51 subfamily E member 2" Q9H255 11 4680171-4697854 "Cancer-related genes, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Transporters" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "blood vessel: 10.4;intestine: 9.2;prostate: 27.2" "Group enriched" "Detected in some" 8 "Neuroendocrine cells: 51.4;Prostatic glandular cells: 148.4;Retinal pigment epithelial cells: 42.6" "Group enriched" "Detected in some" 30 "hippocampal CA1-3: 15.0;vascular associated smooth muscle cell: 20.0" "Cancer enriched" "Detected in some" 166 "Prostate Adenocarcinoma (TCGA): 336.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "lung cancer: 7.4" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Breast - Endothelial cells, Heart muscle - Smooth muscle cells, Prostate - Prostate glandular cells, Skeletal muscle - Smooth muscle cells, Thyroid gland - Smooth muscle cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 48: Non-specific - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" "unprognostic (1.95e-1)" "unprognostic (1.25e-1)" "unprognostic (1.30e-2)" "potential prognostic favorable (1.29e-4)" "unprognostic (2.02e-1)" "unprognostic (1.97e-1)" "unprognostic (1.16e-1)" OR51F1 OR51F1P ENSG00000280021 "Olfactory receptor family 51 subfamily F member 1" A6NGY5 11 4768979-4769938 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR51F2 ENSG00000176925 "Olfactory receptor family 51 subfamily F member 2" Q8NH61 11 4821321-4822456 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 10: Ciliated cells - Ion channel activity" OR51G1 OR51G3P ENSG00000278870 "Olfactory receptor family 51 subfamily G member 1" Q8NGK1 11 4923374-4924339 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR51G2 ENSG00000176893 "Olfactory receptor family 51 subfamily G member 2" Q8NGK0 11 4912588-4919350 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 10: Ciliated cells - Ion channel activity" OR51I1 ENSG00000167359 "Olfactory receptor family 51 subfamily I member 1" Q9H343 11 5440570-5441514 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 9 "olfactory bulb: 4.0" NA NA "Cluster 44: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" OR51I2 ENSG00000187918 "Olfactory receptor family 51 subfamily I member 2" Q9H344 11 5449323-5456518 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Adipocytes: 1.7;Epicardial cells: 6.8;Granulosa cells: 1.6;Hematopoietic stem cells: 4.9;Medullary thymic epithelial cells: 2.4;Retinal ganglion cells: 3.9" "Cell type enhanced" "Detected in some" "deep-layer near-projecting: 4.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 8 "olfactory bulb: 3.6" NA NA "Cluster 51: Myeloma - Immunoglobulins" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" OR51L1 ENSG00000176798 "Olfactory receptor family 51 subfamily L member 1" Q8NGJ5 11 4994851-5005536 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Late primary spermatocytes: 1.6;Late spermatids: 4.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Prostate - Prostate glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 56: Late spermatids - Spermiogenesis: Maturation" OR51M1 ENSG00000184698 "Olfactory receptor family 51 subfamily M member 1" Q9H341 11 5383812-5393263 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "Epicardial cells: 11.4;Oocytes: 27.6" "Group enriched" "Detected in some" 6 "hippocampal CA1-3: 6.3;thalamic excitatory: 3.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA056773 Uncertain NA NA "Cluster 1: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 41: Oocytes - Oogenesis" "HPA056773: " OR51Q1 ENSG00000167360 "Olfactory receptor family 51 subfamily Q member 1" Q8NH59 11 5422111-5423206 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 11 "olfactory bulb: 4.9" HPA044998 Uncertain NA NA "Cluster 1: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "HPA044998: " OR51S1 ENSG00000176922 "Olfactory receptor family 51 subfamily S member 1" Q8NGJ8 11 4848237-4849208 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" OR51T1 ENSG00000176900 "Olfactory receptor family 51 subfamily T member 1" Q8NGJ9 11 4881819-4882883 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA046877 Uncertain NA NA "Cluster 10: Ciliated cells - Ion channel activity" "HPA046877: " OR51V1 OR51A12 ENSG00000176742 "Olfactory receptor family 51 subfamily V member 1" 11 5199735-5200682 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 4 "cerebral cortex: 1.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 52: Neurons & Synapses - Synaptic function" OR52A1 HPFH1OR ENSG00000182070 "Olfactory receptor family 52 subfamily A member 1" Q9UKL2 11 5146824-5154757 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "hippocampal CA1-3: 2.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 48: Non-specific - Mixed function" "Cluster 2: Cerebellar granular cells - Neuronal signaling" OR52A5 ENSG00000171944 "Olfactory receptor family 52 subfamily A member 5" Q9H2C5 11 5128776-5138356 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 4 "Undifferentiated spermatogonia: 5.1" "Cell type enhanced" "Detected in some" "hippocampal CA1-3: 1.2;upper rhombic lip: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 59: Leukemia - T-cell receptor" "Cluster 106: Spermatogonia - Spermatogonial differentiation" OR52B2 ENSG00000255307 "Olfactory receptor family 52 subfamily B member 2" Q96RD2 11 6169355-6170326 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR52B4 ENSG00000221996 "Olfactory receptor family 52 subfamily B member 4" Q8NGK2 11 4367263-4368386 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR52B6 ENSG00000187747 "Olfactory receptor family 52 subfamily B member 6" Q8NGF0 11 5580877-5581884 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 44: Non-specific - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" OR52D1 ENSG00000181609 "Olfactory receptor family 52 subfamily D member 1" Q9H346 11 5488685-5489749 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 12 "testis: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Region enriched" "Detected in single" 14 "olfactory bulb: 4.2" HPA046965 Uncertain NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 44: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "HPA046965: " OR52E1 OR52E1P ENSG00000273085 "Olfactory receptor family 52 subfamily E member 1 (gene/pseudogene)" 11 5069572-5070497 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "cerebral cortex: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" OR52E2 ENSG00000176787 "Olfactory receptor family 52 subfamily E member 2" Q8NGJ4 11 5058650-5059627 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045748 Uncertain NA NA "Cluster 53: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "HPA045748: " OR52E4 ENSG00000180974 "Olfactory receptor family 52 subfamily E member 4" Q8NGH9 11 5880629-5887079 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Early spermatids: 1.7;Late spermatids: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 9: Non-specific - Receptor signaling" "Cluster 56: Non-specific - Sensory perception" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" "unprognostic (1.57e-1)" "unprognostic (5.72e-2)" OR52E5 ENSG00000277932 "Olfactory receptor family 52 subfamily E member 5" Q8NH55 11 5893208-5902730 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 3.1;Differentiating spermatogonia: 1.5;Early primary spermatocytes: 3.7;Epicardial cells: 4.5;Extravillous trophoblasts: 4.5;Late primary spermatocytes: 1.9;Migrating cytotrophoblasts: 2.1;Neuroendocrine cells: 1.4;Parietal cells: 1.8;Retinal ganglion cells: 3.9;Syncytiotrophoblasts: 8.3;Undifferentiated spermatogonia: 3.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" OR52E6 ENSG00000205409 "Olfactory receptor family 52 subfamily E member 6" Q96RD3 11 5840928-5841952 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR52E8 ENSG00000183269 "Olfactory receptor family 52 subfamily E member 8" Q6IFG1 11 5856749-5857690 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR52H1 ENSG00000181616 "Olfactory receptor family 52 subfamily H member 1" Q8NGJ2 11 5544489-5548540 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" NA NA "Cluster 44: Non-specific - Mixed function" "unprognostic (8.14e-3)" OR52I1 ENSG00000232268 "Olfactory receptor family 52 subfamily I member 1" Q8NGK6 11 4593750-4595013 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Papillary tip epithelial cells: 1.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 98: Neurons - Neurotransmission & signaling" "unprognostic (1.46e-1)" "unprognostic (1.26e-2)" "unprognostic (1.71e-3)" "unprognostic (2.04e-1)" "unprognostic (1.82e-1)" "unprognostic (1.44e-1)" "unprognostic (1.24e-1)" "unprognostic (6.37e-2)" OR52I2 ENSG00000226288 "Olfactory receptor family 52 subfamily I member 2" 11 4581743-4593340 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" OR52J3 ENSG00000205495 "Olfactory receptor family 52 subfamily J member 3" Q8NH60 11 5046526-5047461 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 72: Neuronal - Signal transduction" OR52K1 ENSG00000196778 "Olfactory receptor family 52 subfamily K member 1" Q8NGK4 11 4482646-4493497 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 25 "Microglia: 6.6" "Cell type enriched" "Detected in some" 5 "central nervous system macrophage: 8.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 9: Non-specific - Receptor signaling" "Cluster 56: Non-specific - Sensory perception" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" "unprognostic (4.03e-2)" "unprognostic (3.33e-2)" OR52K2 ENSG00000181963 "Olfactory receptor family 52 subfamily K member 2" Q8NGK3 11 4449295-4450361 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "neutrophil: 3.3" "Lineage enhanced" "Detected in single" "granulocytes: 3.3" "Not detected" "Not detected" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 43: Hindbrain - Mixed function" "unprognostic (2.29e-1)" OR52L1 ENSG00000183313 "Olfactory receptor family 52 subfamily L member 1" Q8NGH7 11 5985892-5986985 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 1 OR52M1 OR52M1P ENSG00000197790 "Olfactory receptor family 52 subfamily M member 1" Q8NGK5 11 4545191-4546144 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR52N1 ENSG00000181001 "Olfactory receptor family 52 subfamily N member 1" Q8NH53 11 5786471-5791265 "Cancer-related genes, G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA054028 Uncertain NA NA "Cluster 9: Non-specific - Receptor signaling" "HPA054028: " OR52N2 ENSG00000180988 "Olfactory receptor family 52 subfamily N member 2" Q8NGI0 11 5808924-5821483 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Early spermatids: 4.5;Gastric chief cells: 1.1;Hematopoietic stem cells: 1.5;Late spermatids: 6.1;Neutrophil progenitors: 1.3;Parietal cells: 1.8;Retinal ganglion cells: 3.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 36 "basophil: 4.0" "Lineage enriched" "Detected in single" 36 "granulocytes: 4.0" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" OR52N4 ENSG00000181074 "Olfactory receptor family 52 subfamily N member 4" Q8NGI2 11 5754243-5755958 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 2.7" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "central nervous system macrophage: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Spleen - B-cells (Spleen), Thyroid gland - T-cells" "Not detected" "Not detected" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 22: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" "unprognostic (2.50e-2)" OR52N5 OR52N5Q ENSG00000181009 "Olfactory receptor family 52 subfamily N member 5" Q8NH56 11 5776165-5783355 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 9: Non-specific - Receptor signaling" OR52P1 OR52P1P ENSG00000181109 "Olfactory receptor family 52 subfamily P member 1 (gene/pseudogene)" 11 5726502-5727464 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR52R1 ENSG00000279270 "Olfactory receptor family 52 subfamily R member 1" Q8NGF1 11 4803433-4804380 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 10: Ciliated cells - Ion channel activity" OR52W1 OR52W1P ENSG00000175485 "Olfactory receptor family 52 subfamily W member 1" Q6IF63 11 6199224-6200186 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 51: Neurons - Mixed function" OR56A1 ENSG00000180934 "Olfactory receptor family 56 subfamily A member 1" 11 6019336-6034338 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Neutrophils: 1.3;Podocytes: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" NA NA "Cluster 9: Non-specific - Receptor signaling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" "unprognostic (2.11e-2)" OR56A3 "OR56A3P, OR56A6" ENSG00000184478 "Olfactory receptor family 56 subfamily A member 3" Q8NH54 11 5938751-5951347 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 3.7;Early primary spermatocytes: 2.4;Early spermatids: 1.0;Extravillous trophoblasts: 1.8;Late primary spermatocytes: 4.6;Late spermatids: 1.1;Migrating cytotrophoblasts: 2.1;Retinal ganglion cells: 3.9;Syncytiotrophoblasts: 2.4;Undifferentiated spermatogonia: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 56: Non-specific - Sensory perception" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" OR56A4 ENSG00000183389 "Olfactory receptor family 56 subfamily A member 4" Q8NGH8 11 5999445-6006946 "Essential proteins, G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Group enriched" "Detected in some" 14 "Early spermatids: 5.5;Late spermatids: 9.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" NA NA "Cluster 9: Non-specific - Receptor signaling" "Cluster 56: Non-specific - Sensory perception" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" "unprognostic (1.95e-2)" OR56A5 OR56A5P ENSG00000188691 "Olfactory receptor family 56 subfamily A member 5" P0C7T3 11 5967177-5968494 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 56: Late spermatids - Spermiogenesis: Maturation" OR56B1 OR56B1P ENSG00000181023 "Olfactory receptor family 56 subfamily B member 1" Q8NGI3 11 5736448-5738523 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045043 Uncertain NA NA "Cluster 87: B-cells - Adaptive immunity: Humoral response" "HPA045043: " OR56B2P OR56B2 ENSG00000181017 "Olfactory receptor family 56 subfamily B member 2 pseudogene" 11 5761153-5769080 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "B-cells: 1.9;Fibro-adipogenic progenitors: 1.0;Hematopoietic stem cells: 3.9;Megakaryocyte-Erythroid progenitors: 1.1" "Cell type enhanced" "Detected in single" "deep-layer near-projecting: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 9: Non-specific - Receptor signaling" "Cluster 87: B-cells - Adaptive immunity: Humoral response" OR56B4 ENSG00000180919 "Olfactory receptor family 56 subfamily B member 4" Q8NH76 11 6107684-6108835 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 56: Non-specific - Sensory perception" OR5A1 "OR5A1P, OST181" ENSG00000172320 "Olfactory receptor family 5 subfamily A member 1" Q8NGJ0 11 59436469-59451380 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Early spermatids: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 9: Non-specific - Receptor signaling" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" "unprognostic (4.15e-2)" "unprognostic (1.51e-3)" OR5A2 ENSG00000172324 "Olfactory receptor family 5 subfamily A member 2" Q8NGI9 11 59416969-59426413 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in single" "Cell type enhanced" "Detected in single" "Late spermatids: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047135, HPA049575" Uncertain NA NA "Cluster 40: Non-specific - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" "HPA047135: , HPA049575: " "unprognostic (7.48e-2)" "unprognostic (1.57e-1)" OR5AC1 OR5AC1P ENSG00000213439 "Olfactory receptor family 5 subfamily AC member 1 (gene/pseudogene)" 3 98064472-98065396 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR5AC2 HSA1 ENSG00000196578 "Olfactory receptor family 5 subfamily AC member 2" Q9NZP5 3 98087173-98088102 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "Early spermatids: 2.3;Late primary spermatocytes: 1.6;Late spermatids: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" OR5AK2 ENSG00000181273 "Olfactory receptor family 5 subfamily AK member 2" Q8NH90 11 56988914-56989843 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 36 "lymphoid tissue: 5.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 5: Spleen - Immune response" "Cluster 22: Non-specific - Mixed function" "Cluster 65: Non-specific - Unknown function" OR5AK3P OR5AK3 ENSG00000181282 "Olfactory receptor family 5 subfamily AK member 3 pseudogene" 11 56971050-56971979 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "white matter: 1.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 22: Non-specific - Mixed function" "Cluster 65: Non-specific - Unknown function" OR5AL1 OR5AL1P ENSG00000272987 "Olfactory receptor family 5 subfamily AL member 1 (gene/pseudogene)" 11 56412696-56413680 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR5AN1 ENSG00000176495 "Olfactory receptor family 5 subfamily AN member 1" Q8NGI8 11 59358895-59371714 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 9: Non-specific - Receptor signaling" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" OR5AP2 ENSG00000172464 "Olfactory receptor family 5 subfamily AP member 2" Q8NGF4 11 56641489-56642439 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 69: Skin cancer - ECM organization" OR5AR1 ENSG00000172459 "Olfactory receptor family 5 subfamily AR member 1" Q8NGP9 11 56663686-56664618 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 69: Skin cancer - ECM organization" OR5AS1 ENSG00000181785 "Olfactory receptor family 5 subfamily AS member 1" Q8N127 11 56027654-56038191 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "retina: 2.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 40: Non-specific - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 56: Non-specific - Sensory perception" 1 "unprognostic (9.51e-2)" "unprognostic (1.43e-3)" "unprognostic (7.01e-2)" "unprognostic (2.41e-2)" "potential prognostic favorable (1.88e-4)" "unprognostic (3.32e-1)" "unprognostic (3.92e-2)" "unprognostic (3.21e-1)" OR5AU1 ENSG00000169327 "Olfactory receptor family 5 subfamily AU member 1" Q8NGC0 14 21148370-21159060 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 1.7;Endometrial glandular cells: 3.5;Endometrial luminal cells: 5.0;Endometrial stromal cells: 1.2;Epididymal basal cells: 2.0;Epididymal clear cells: 2.0;Mesothelial cells: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 48: Non-specific - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" "unprognostic (4.70e-3)" OR5B12 "OR5B12P, OR5B16, OST743" ENSG00000172362 "Olfactory receptor family 5 subfamily B member 12" Q96R08 11 58438994-58442236 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 46: Skeletal myocytes - Muscle structure & formation" OR5B17 OR5B20P ENSG00000197786 "Olfactory receptor family 5 subfamily B member 17" Q8NGF7 11 58358124-58359069 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR5B2 OST073 ENSG00000172365 "Olfactory receptor family 5 subfamily B member 2" Q96R09 11 58421238-58428121 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" OR5B21 ENSG00000198283 "Olfactory receptor family 5 subfamily B member 21" A6NL26 11 58506807-58508105 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "pDCs: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 71: Lymphoma - Inflammatory response" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" OR5B3 "OR5B13, OST129" ENSG00000172769 "Olfactory receptor family 5 subfamily B member 3" Q8NH48 11 58402464-58406874 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 56: Non-specific - Sensory perception" OR5BS1P OR5BS1 ENSG00000198678 "Olfactory receptor family 5 subfamily BS member 1 pseudogene" 12 48559882-48562956 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 9 "Breast lactating cells: 3.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 4: Breast lactating luminal cells - Lactation" OR5C1 "hRPK-465_F_21, OR5C2P, OR9-F" ENSG00000148215 "Olfactory receptor family 5 subfamily C member 1" Q8NGR4 9 122788933-122789895 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Platelets: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 6: Non-specific - Immune response" "Cluster 47: Platelets - Hemostasis" OR5D13 ENSG00000279761 "Olfactory receptor family 5 subfamily D member 13" Q8NGL4 11 55773438-55774382 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 53: Squamous epithelial cells - Keratinization" OR5D14 ENSG00000186113 "Olfactory receptor family 5 subfamily D member 14" Q8NGL3 11 55795556-55796500 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR5D16 ENSG00000205029 "Olfactory receptor family 5 subfamily D member 16" Q8NGK9 11 55838752-55839738 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA046711 Uncertain NA NA "HPA046711: " OR5D18 ENSG00000186119 "Olfactory receptor family 5 subfamily D member 18" Q8NGL1 11 55819630-55820571 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 1: Neuronal - Visual perception" OR5D3P "OR11-8b, OR11-8c, OR5D3, OR5D4" ENSG00000186886 "Olfactory receptor family 5 subfamily D member 3 pseudogene" 11 55723776-55729621 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" OR5F1 OR11-10 ENSG00000149133 "Olfactory receptor family 5 subfamily F member 1" O95221 11 55993681-55994625 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA059360 Uncertain NA NA "HPA059360: " OR5G3 "OR5G3P, OR5G6P" ENSG00000241356 "Olfactory receptor family 5 subfamily G member 3 (gene/pseudogene)" 11 56819573-56820516 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 8 "lymphoid tissue: 1.4;salivary gland: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 5: Spleen - Immune response" "Cluster 65: Non-specific - Unknown function" OR5H1 "HSHTPCRX14, HTPCRX14" ENSG00000231192 "Olfactory receptor family 5 subfamily H member 1" A6NKK0 3 98130721-98138548 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" NA NA "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 55: Lymphoma - Immune response" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." 1 OR5H14 ENSG00000236032 "Olfactory receptor family 5 subfamily H member 14" A6NHG9 3 98147479-98156614 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Early spermatids: 1.9;Late primary spermatocytes: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" NA NA "Cluster 9: Non-specific - Receptor signaling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" OR5H15 ENSG00000233412 "Olfactory receptor family 5 subfamily H member 15" A6NDH6 3 98166696-98169774 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR5H2 ENSG00000197938 "Olfactory receptor family 5 subfamily H member 2" Q8NGV7 3 98282505-98284070 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 55: Lymphoma - Immune response" OR5H6 ENSG00000230301 "Olfactory receptor family 5 subfamily H member 6" Q8NGV6 3 98263252-98265356 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 55: Lymphoma - Immune response" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" OR5H8 OR5H8P ENSG00000232535 "Olfactory receptor family 5 subfamily H member 8 (gene/pseudogene)" 3 98306752-98312843 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 55: Lymphoma - Immune response" OR5I1 "HSOlf1, OLF1" ENSG00000167825 "Olfactory receptor family 5 subfamily I member 1" Q13606 11 55935456-55936400 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR5J2 ENSG00000174957 "Olfactory receptor family 5 subfamily J member 2" Q8NH18 11 56176618-56177556 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA059466 Uncertain NA NA "Cluster 69: Skin cancer - ECM organization" "HPA059466: " OR5K1 "HSHTPCRX10, HTPCRX10" ENSG00000232382 "Olfactory receptor family 5 subfamily K member 1" Q8NHB7 3 98463201-98472924 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 4 "Cardiomyocytes: 9.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" OR5K2 ENSG00000231861 "Olfactory receptor family 5 subfamily K member 2" Q8NHB8 3 98497681-98498631 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 17 "Cardiomyocytes: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 38: Non-specific - Transcription" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" "unprognostic (1.93e-1)" OR5K3 ENSG00000206536 "Olfactory receptor family 5 subfamily K member 3" A6NET4 3 98390666-98391631 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 55: Lymphoma - Immune response" OR5K4 ENSG00000196098 "Olfactory receptor family 5 subfamily K member 4" A6NMS3 3 98353854-98354819 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 55: Lymphoma - Immune response" OR5L1 OST262 ENSG00000279395 "Olfactory receptor family 5 subfamily L member 1" Q8NGL2 11 55811367-55812476 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047524 Uncertain NA NA "HPA047524: " OR5L2 "HSHTPCRX16, HTPCRX16" ENSG00000205030 "Olfactory receptor family 5 subfamily L member 2" Q8NGL0 11 55827219-55828154 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047524 Uncertain NA NA "HPA047524: " OR5M1 OST050 ENSG00000255012 "Olfactory receptor family 5 subfamily M member 1" Q8NGP8 11 56609236-56614874 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Inner root sheath cells" NA NA OR5M10 ENSG00000254834 "Olfactory receptor family 5 subfamily M member 10" Q6IEU7 11 56576774-56577721 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR5M11 OR11-199 ENSG00000255223 "Olfactory receptor family 5 subfamily M member 11" Q96RB7 11 56542340-56543257 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 13 "Late spermatids: 4.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" OR5M3 ENSG00000174937 "Olfactory receptor family 5 subfamily M member 3" Q8NGP4 11 56469274-56473352 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA OR5M8 ENSG00000181371 "Olfactory receptor family 5 subfamily M member 8" Q8NGP6 11 56490435-56491370 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR5M9 ENSG00000150269 "Olfactory receptor family 5 subfamily M member 9" Q8NGP3 11 56462469-56463401 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR5P2 JCG3 ENSG00000183303 "Olfactory receptor family 5 subfamily P member 2" Q8WZ92 11 7795974-7796942 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR5P3 JCG1 ENSG00000182334 "Olfactory receptor family 5 subfamily P member 3" Q8WZ94 11 7824818-7830840 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA060787 Uncertain NA NA "HPA060787: " OR5T1 OR5T1P ENSG00000181698 "Olfactory receptor family 5 subfamily T member 1" Q8NG75 11 56274154-56276819 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA050952 Uncertain NA NA "HPA050952: " OR5T2 ENSG00000181718 "Olfactory receptor family 5 subfamily T member 2" 11 56231282-56234255 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 56: Non-specific - Sensory perception" OR5T3 OR5T3Q ENSG00000172489 "Olfactory receptor family 5 subfamily T member 3" 11 56252254-56253222 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR5V1 hs6M1-21 ENSG00000243729 "Olfactory receptor family 5 subfamily V member 1" Q9UGF6 6 29353749-29431967 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 28 "Ependymal cells: 55.7" "Cell type enriched" "Detected in some" 4 "ependymal cell: 85.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA046707 Uncertain NA NA "Cluster 46: Brainstem - Mixed function" "Cluster 34: Ciliated cells - Cilia assembly & function" "HPA046707: " OR5W2 "OR5W2P, OR5W3P" ENSG00000187612 "Olfactory receptor family 5 subfamily W member 2" Q8NH69 11 55913650-55914582 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR6A2 "OR11-55, OR6A1, OR6A2P" ENSG00000184933 "Olfactory receptor family 6 subfamily A member 2" O95222 11 6791736-6799689 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 3.6;Brain inhibitory neurons: 5.8;Cone photoreceptor cells: 6.2;Early spermatids: 2.6;Ependymal cells: 2.6;Oocytes: 4.6;Other brain neurons: 3.5;Plasma cells: 3.8;Sertoli cells: 6.2;Undifferentiated spermatogonia: 3.3" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 32: Cerebral cortex - Mixed function" "Cluster 35: Neurons - Synaptic function & neurogenesis" OR6B1 OR7-3 ENSG00000221813 "Olfactory receptor family 6 subfamily B member 1" O95007 7 144000320-144008793 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" HPA053164 Uncertain NA NA "Cluster 9: Non-specific - Receptor signaling" "Cluster 51: Myeloma - Immunoglobulins" 3 "HPA053164: " OR6B2 OR6B2P ENSG00000182083 "Olfactory receptor family 6 subfamily B member 2" Q6IFH4 2 240029491-240030429 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" HPA047529 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" "Plasma membrane" Cytosol "HPA047529: " OR6B3 "OR6B3P, OR6B3Q" ENSG00000178586 "Olfactory receptor family 6 subfamily B member 3" Q8NGW1 2 240044571-240053521 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 20 "retina: 19.3" "Cell type enriched" "Detected in some" 5 "Rod photoreceptor cells: 33.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047529 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 42: Retina - Visual perception" "Cluster 79: Photoreceptor cells - Phototransduction" "Plasma membrane" Cytosol "HPA047529: " OR6C1 OST267 ENSG00000205330 "Olfactory receptor family 6 subfamily C member 1" Q96RD1 12 55314343-55322364 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 87: B-cells - Adaptive immunity: Humoral response" OR6C2 OR6C67 ENSG00000179695 "Olfactory receptor family 6 subfamily C member 2" Q9NZP2 12 55444069-55453347 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Breast lactating cells: 1.7;Cardiomyocytes: 2.6;Esophageal apical cells: 1.5;Gastric progenitor cells: 1.3;Papillary tip epithelial cells: 2.0;Parietal cells: 1.8;Prostatic hillock cells: 1.2;Salivary acinar cells: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" OR6C3 OST709 ENSG00000205329 "Olfactory receptor family 6 subfamily C member 3" Q9NZP0 12 55330043-55332687 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR6C4 ENSG00000179626 "Olfactory receptor family 6 subfamily C member 4" Q8NGE1 12 55549602-55555832 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 20 "Cardiomyocytes: 4.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 9: Non-specific - Receptor signaling" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" OR6C6 ENSG00000188324 "Olfactory receptor family 6 subfamily C member 6" A6NF89 12 55293988-55296569 "Essential proteins, G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA051090 Uncertain Approved "Lipid droplets,Plasma membrane" NA NA "Cluster 48: Non-specific - Mixed function" "Cluster 103: Non-specific - Basic cellular processes" "Lipid droplets, Plasma membrane" "HPA051090: " OR6C65 ENSG00000205328 "Olfactory receptor family 6 subfamily C member 65" A6NJZ3 12 55400529-55401467 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR6C68 ENSG00000205327 "Olfactory receptor family 6 subfamily C member 68" A6NDL8 12 55492378-55493316 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 5 "Cardiomyocytes: 5.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" NA NA "Cluster 50: Lymphoma - Unknown function" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" OR6C70 ENSG00000184954 "Olfactory receptor family 6 subfamily C member 70" A6NIJ9 12 55469200-55470138 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 53: Squamous epithelial cells - Keratinization" OR6C74 ENSG00000197706 "Olfactory receptor family 6 subfamily C member 74" A6NCV1 12 55244609-55256625 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 9: Non-specific - Receptor signaling" "Cluster 7: Liver cancer - Metabolism" "Cluster 46: Skeletal myocytes - Muscle structure & formation" OR6C75 ENSG00000187857 "Olfactory receptor family 6 subfamily C member 75" A6NL08 12 55362975-55369279 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 110: Mural cells - ECM organization" OR6C76 ENSG00000185821 "Olfactory receptor family 6 subfamily C member 76" A6NM76 12 55426254-55427192 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR6F1 OST731 ENSG00000169214 "Olfactory receptor family 6 subfamily F member 1" Q8NGZ6 1 247711436-247716646 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Early spermatids: 5.5;Late primary spermatocytes: 9.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" NA NA "Cluster 72: Neuronal - Signal transduction" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" OR6J1 "OR6J1P, OR6J2" ENSG00000255804 "Olfactory receptor family 6 subfamily J member 1" Q8NGC5 14 22630929-22644352 "Essential proteins, G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 6 "Cone photoreceptor cells: 33.1" "Cell type enhanced" "Detected in some" "astrocyte: 2.9;Bergmann glia: 1.9;ependymal cell: 1.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 48: Non-specific - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 79: Photoreceptor cells - Phototransduction" "unprognostic (1.27e-1)" "unprognostic (1.22e-1)" OR6K2 ENSG00000196171 "Olfactory receptor family 6 subfamily K member 2" Q8NGY2 1 158699678-158700652 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR6K3 ENSG00000203757 "Olfactory receptor family 6 subfamily K member 3" Q8NGY3 1 158716327-158720720 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 5 "bone marrow: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 20 "basophil: 8.2" "Lineage enriched" "Detected in single" 22 "granulocytes: 8.2" "Not detected" "Not detected" HPA055949 Uncertain NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 15: Bone marrow - Innate immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 37: Neutrophil progenitors - Granulopoiesis" "HPA055949: " OR6K6 ENSG00000180433 "Olfactory receptor family 6 subfamily K member 6" 1 158754720-158755891 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 38 "basophil: 3.7" "Lineage enriched" "Detected in single" 38 "granulocytes: 3.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 34: Testis cancer - Unknown function" OR6M1 ENSG00000196099 "Olfactory receptor family 6 subfamily M member 1" Q8NGM8 11 123805408-123806349 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 5 "Early spermatids: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA048674 Uncertain NA NA "Cluster 30: Non-specific - Gene expression regulation" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "HPA048674: " OR6N1 ENSG00000197403 "Olfactory receptor family 6 subfamily N member 1" Q8NGY5 1 158747814-158772195 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 10 "Neutrophil progenitors: 39.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 25 "basophil: 5.1" "Lineage enriched" "Detected in single" 52 "granulocytes: 5.1" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 37: Neutrophil progenitors - Granulopoiesis" OR6N2 ENSG00000188340 "Olfactory receptor family 6 subfamily N member 2" Q8NGY6 1 158774222-158781204 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 11 "bone marrow: 1.0" "Cell type enriched" "Detected in single" 8 "Neutrophil progenitors: 5.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA056637 Uncertain NA NA "Cluster 15: Bone marrow - Innate immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" "HPA056637: " OR6P1 ENSG00000186440 "Olfactory receptor family 6 subfamily P member 1" Q8NGX9 1 158560606-158570580 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Late spermatids: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047466 Uncertain Approved "Mid piece,Principal piece" NA NA "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" "Mid piece, Principal piece" "HPA047466: " OR6Q1 ENSG00000279051 "Olfactory receptor family 6 subfamily Q member 1" Q8NGQ2 11 58030953-58031906 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 7: Liver cancer - Metabolism" OR6S1 OR6S1Q ENSG00000181803 "Olfactory receptor family 6 subfamily S member 1" Q8NH40 14 20640696-20641691 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 55: Lymphoma - Immune response" OR6T1 ENSG00000181499 "Olfactory receptor family 6 subfamily T member 1" Q8NGN1 11 123942867-123943838 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA060893 Uncertain NA NA "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "HPA060893: " OR6V1 GPR138 ENSG00000225781 "Olfactory receptor family 6 subfamily V member 1" Q8N148 7 143052341-143053282 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR6X1 ENSG00000221931 "Olfactory receptor family 6 subfamily X member 1" Q8NH79 11 123753580-123754518 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR6Y1 OR6Y2 ENSG00000197532 "Olfactory receptor family 6 subfamily Y member 1" Q8NGX8 1 158544550-158554405 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "retina: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 40: Non-specific - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 56: Non-specific - Sensory perception" "Cluster 110: Mural cells - ECM organization" "unprognostic (3.16e-2)" "unprognostic (6.56e-2)" "unprognostic (3.24e-1)" OR7A10 ENSG00000127515 "Olfactory receptor family 7 subfamily A member 10" O76100 19 14840466-14848922 "Essential proteins, G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 97: Non-specific - Cellular respiration" 1 OR7A17 HTPCRX19 ENSG00000185385 "Olfactory receptor family 7 subfamily A member 17" O14581 19 14878203-14886132 "Essential proteins, G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Retinal bipolar cells: 1.7;Sertoli cells: 2.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 48: Non-specific - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 4 "unprognostic (1.96e-2)" "unprognostic (2.21e-1)" OR7A5 HTPCR2 ENSG00000188269 "Olfactory receptor family 7 subfamily A member 5" Q15622 19 14826241-14835185 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 2.6;epididymis: 4.2;parathyroid gland: 6.6" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Skin Cutaneous Melanoma (TCGA): 3.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pituitary gland - Somatotropes, Prostate - Prostate basal glandular cells" HPA053823 Uncertain NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "HPA053823: " "unprognostic (1.78e-2)" OR7C1 "OR19-5, OR7C4" ENSG00000127530 "Olfactory receptor family 7 subfamily C member 1" O76099 19 14789260-14835376 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "parathyroid gland: 6.4" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 28.9;Epididymal principal cells: 7.7;Melanocytes: 44.0;Prostatic glandular cells: 15.5;Sertoli cells: 21.0;Somatotrophs: 29.4;Tuft cells: 11.5" "Cell type enriched" "Detected in some" 13 "pericyte: 63.5" "Cancer enhanced" "Detected in single" "Skin Cutaneous Melanoma (TCGA): 2.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 3.2" "Lineage enriched" "Detected in single" 4 "granulocytes: 3.2" "Not detected" "Not detected" "Pituitary gland - Somatotropes, Prostate - Prostate basal glandular cells" HPA047127 Uncertain NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 61: Schwann cells & Melanocytes - Mixed function" 1 "HPA047127: " "unprognostic (2.29e-1)" "unprognostic (1.46e-3)" "unprognostic (1.21e-1)" OR7C2 "OR19-18, OR7C3" ENSG00000127529 "Olfactory receptor family 7 subfamily C member 2" O60412 19 14941489-14942448 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047295 Uncertain NA NA 1 "HPA047295: " OR7D2 "FLJ38149, HTPCRH03, OR19-4" ENSG00000188000 "Olfactory receptor family 7 subfamily D member 2" Q96RA2 19 9178979-9188818 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "testis: 1.1" "Group enriched" "Detected in some" 4 "Early spermatids: 16.7;Late primary spermatocytes: 7.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" NA NA "Cluster 47: Testis - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 56: Non-specific - Sensory perception" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 1 "unprognostic (9.05e-3)" "unprognostic (5.82e-3)" "unprognostic (7.93e-3)" "unprognostic (3.29e-1)" "unprognostic (3.79e-2)" OR7D4 "hg105, OR19-B, OR7D4P" ENSG00000174667 "Olfactory receptor family 7 subfamily D member 4" Q8NG98 19 9210276-9219589 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Testicular Germ Cell Tumor (TCGA): 3.3;Uterine Corpus Endometrial Carcinoma (TCGA): 1.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Lineage enriched" "Detected in single" 7 "granulocytes: 1.3" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" NA NA "Cluster 48: Non-specific - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 2 "unprognostic (1.10e-2)" "unprognostic (4.64e-1)" "unprognostic (7.68e-2)" OR7E24 "HSHT2, OR19-8, OR7E24P, OR7E24Q" ENSG00000237521 "Olfactory receptor family 7 subfamily E member 24" Q6IFN5 19 9247344-9252625 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 10 "testis: 1.5" "Cell type enriched" "Detected in some" 4 "Oocytes: 64.5" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "Testicular Germ Cell Tumor (TCGA): 3.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 15: Kidney cancer - Membrane components" "Cluster 41: Oocytes - Oogenesis" "unprognostic (1.34e-1)" OR7G1 "OR19-15, OR7G1P" ENSG00000161807 "Olfactory receptor family 7 subfamily G member 1" Q8NGA0 19 9114828-9115763 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 1 OR7G2 OST260 ENSG00000170923 "Olfactory receptor family 7 subfamily G member 2" Q8NG99 19 9100407-9107475 "Essential proteins, G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 1.5;neutrophil: 1.3" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 48: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 68: Foveolar cells - Mucosal defense" "unprognostic (2.81e-1)" OR7G3 OST085 ENSG00000170920 "Olfactory receptor family 7 subfamily G member 3" Q8NG95 19 9126012-9126950 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 51: Myeloma - Immunoglobulins" "unprognostic (9.27e-2)" OR8A1 OST025 ENSG00000196119 "Olfactory receptor family 8 subfamily A member 1" Q8NGG7 11 124566660-124582942 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 2.5;Early primary spermatocytes: 2.3;Early spermatids: 4.6;Extravillous trophoblasts: 1.9;Foveolar cells: 1.5;Late primary spermatocytes: 1.7;Late spermatids: 3.6;Mast cells: 2.5;Oocytes: 4.6;Other brain neurons: 10.2;pDCs: 1.8;Undifferentiated spermatogonia: 5.3" "Cell type enhanced" "Detected in some" "mammillary body: 1.6;splatter: 1.8;thalamic excitatory: 2.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Gallbladder cancer: 1.4" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 9: Non-specific - Receptor signaling" "Cluster 56: Non-specific - Sensory perception" "Cluster 109: Neurons - Neuronal signaling" "unprognostic (5.78e-2)" "unprognostic (1.57e-3)" OR8B12 ENSG00000170953 "Olfactory receptor family 8 subfamily B member 12" Q8NGG6 11 124539635-124545333 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 19 "Platelets: 5.6" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 33: Neurons - Mixed function" "Cluster 47: Platelets - Hemostasis" OR8B2 ENSG00000284680 "Olfactory receptor family 8 subfamily B member 2" Q96RD0 11 124382394-124384499 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 11 "testis: 1.1" "Group enriched" "Detected in some" 6 "Early spermatids: 54.0;Late spermatids: 48.7" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebral cortex: 1.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" OR8B3 ENSG00000284609 "Olfactory receptor family 8 subfamily B member 3" Q8NGG8 11 124395534-124399024 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 6 "Early spermatids: 18.7" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebral cortex: 1.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" NA NA "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" OR8B4 OR8B4P ENSG00000280090 "Olfactory receptor family 8 subfamily B member 4" Q96RC9 11 124423942-124424871 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebral cortex: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 56: Hypothalamus - Neuropeptide signaling" OR8B8 TPCR85 ENSG00000197125 "Olfactory receptor family 8 subfamily B member 8" Q15620 11 124437445-124445696 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 4 "Mast cells: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 48: Non-specific - Mixed function" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" OR8D1 "OR8D3, OST004" ENSG00000196341 "Olfactory receptor family 8 subfamily D member 1" Q8WZ84 11 124302831-124315099 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA059510 Uncertain NA NA "Cluster 32: Cerebral cortex - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" "HPA059510: " OR8D2 ENSG00000279116 "Olfactory receptor family 8 subfamily D member 2" Q9GZM6 11 124319262-124320197 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebral cortex: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 56: Hypothalamus - Neuropeptide signaling" OR8D4 ENSG00000181518 "Olfactory receptor family 8 subfamily D member 4" Q8NGM9 11 123902167-123909229 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 2.2;Goblet cells: 3.0;Granulosa cells: 25.1;Oocytes: 4.6;Pancreatic acinar cells: 10.5;Renal connecting tubule cells: 2.6;Sertoli cells: 18.5" "Cell type enhanced" "Detected in some" "amygdala excitatory: 2.2;miscellaneous: 2.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 48: Non-specific - Mixed function" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" OR8G1 "HSTPCR25, OR8G1P, TPCR25" ENSG00000197849 "Olfactory receptor family 8 subfamily G member 1" Q15617 11 124241095-124254364 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Early primary spermatocytes: 5.7;Early spermatids: 12.4;Late primary spermatocytes: 13.2;Late spermatids: 6.1;Undifferentiated spermatogonia: 5.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" OR8G2P "HSTPCR120, OR8G2, OR8G4, ORL206, ORL486, TPCR120" ENSG00000181214 "Olfactory receptor family 8 subfamily G member 2 pseudogene" 11 124224732-124225666 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR8G3P ENSG00000255425 "Olfactory receptor family 8 subfamily G member 3 pseudogene" 11 124211707-124215828 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 1.1;Early primary spermatocytes: 2.9;Early spermatids: 2.2;Late primary spermatocytes: 1.3;Late spermatids: 5.8;Oocytes: 9.2;Undifferentiated spermatogonia: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Gallbladder cancer: 1.6" "Testis - Early spermatids" NA NA "Cluster 51: Myeloma - Immunoglobulins" "Cluster 41: Oocytes - Oogenesis" OR8G5 "OR8G5P, OR8G6" ENSG00000255298 "Olfactory receptor family 8 subfamily G member 5" 11 124256376-124266224 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 19 "testis: 2.5" "Group enriched" "Detected in some" 7 "Early spermatids: 30.2;Late primary spermatocytes: 24.9;Late spermatids: 45.9;Oocytes: 36.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" OR8H1 ENSG00000181693 "Olfactory receptor family 8 subfamily H member 1" Q8NGG4 11 56288462-56292254 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 48: Non-specific - Mixed function" OR8H2 ENSG00000181767 "Olfactory receptor family 8 subfamily H member 2" Q8N162 11 56103687-56107658 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 35: Non-specific - DNA binding" "Cluster 7: Liver cancer - Metabolism" OR8H3 ENSG00000181761 "Olfactory receptor family 8 subfamily H member 3" Q8N146 11 56122373-56123311 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 7: Liver cancer - Metabolism" OR8I2 ENSG00000172154 "Olfactory receptor family 8 subfamily I member 2" Q8N0Y5 11 56093308-56094240 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR8J1 ENSG00000172487 "Olfactory receptor family 8 subfamily J member 1" Q8NGP2 11 56354291-56361511 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR8J2 OR8J2P ENSG00000254658 "Olfactory receptor family 8 subfamily J member 2 (gene/pseudogene)" 11 56208985-56215222 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR8J3 ENSG00000167822 "Olfactory receptor family 8 subfamily J member 3" Q8NGG0 11 56134721-56140201 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR8K1 ENSG00000150261 "Olfactory receptor family 8 subfamily K member 1" Q8NGG5 11 56346039-56346998 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA055233 Uncertain NA NA "HPA055233: " OR8K3 ENSG00000280314 "Olfactory receptor family 8 subfamily K member 3 (gene/pseudogene)" Q8NH51 11 56315144-56320639 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR8K5 ENSG00000181752 "Olfactory receptor family 8 subfamily K member 5" Q8NH50 11 56159394-56160317 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "Stomach Adenocarcinoma (TCGA): 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 15: Kidney cancer - Membrane components" OR8S1 ENSG00000284723 "Olfactory receptor family 8 subfamily S member 1" 12 48525632-48526570 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 59: Leukemia - T-cell receptor" OR8U1 ENSG00000172199 "Olfactory receptor family 8 subfamily U member 1" Q8NH10 11 56375624-56376553 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR8U3 "OR5R1, OR5R1P" ENSG00000279961 "Olfactory receptor family 8 subfamily U member 3" Q8NH85 11 56417258-56418232 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR9A1P "HSHTPCRX06, HTPCRX06, OR9A1" ENSG00000237621 "Olfactory receptor family 9 subfamily A member 1 pseudogene" 7 141887148-141888092 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 32: Cerebral cortex - Mixed function" OR9A2 ENSG00000179468 "Olfactory receptor family 9 subfamily A member 2" Q8NGT5 7 143026200-143027132 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 80: Oligodendrocytes - Myelination" "unprognostic (2.95e-3)" OR9A4 ENSG00000258083 "Olfactory receptor family 9 subfamily A member 4" Q8NGU2 7 141916399-141920625 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Gallbladder cancer: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 19: Astrocytes - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "unprognostic (2.24e-1)" OR9G1 OR9G5 ENSG00000174914 "Olfactory receptor family 9 subfamily G member 1" Q8NH87 11 56699095-56703884 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 35: Non-specific - DNA binding" OR9G4 ENSG00000172457 "Olfactory receptor family 9 subfamily G member 4" 11 56741223-56748697 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR9H1P ENSG00000228336 "Olfactory receptor family 9 subfamily H member 1 pseudogene" 1 247770169-247779524 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 1.2;Early primary spermatocytes: 2.8;Kupffer cells: 1.0;Lacrimal acinar cells: 2.7;Late spermatids: 1.0;Pituitary stem cells: 2.3;Prostatic glandular cells: 1.4;Thymocytes: 2.5;Undifferentiated spermatogonia: 1.1" "Cell type enhanced" "Detected in some" "lower rhombic lip: 5.1;mammillary body: 3.2" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" NA NA "Cluster 32: Cerebral cortex - Mixed function" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" OR9I1 ENSG00000172377 "Olfactory receptor family 9 subfamily I member 1" Q8NGQ6 11 58116742-58125530 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" OR9K2 ENSG00000170605 "Olfactory receptor family 9 subfamily K member 2" 12 55126406-55132750 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA015808 Uncertain NA NA "HPA015808: " OR9Q1 ENSG00000186509 "Olfactory receptor family 9 subfamily Q member 1" Q8NGQ5 11 58023881-58181616 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Epicardial cells: 9.1;Epididymal efferent duct ciliated cells: 6.3;Oocytes: 4.6;Pancreatic duct cells: 14.4;Paneth cells: 3.9;Proximal tubule cells: 15.0;Retinal pigment epithelial cells: 4.3;Sertoli cells: 16.3" "Cell type enhanced" "Detected in some" "miscellaneous: 6.5;upper-layer intratelencephalic: 9.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 88: Proximal tubular cells - Transmembrane transport" OR9Q2 OR9Q2P ENSG00000186513 "Olfactory receptor family 9 subfamily Q member 2" Q8NGE9 11 58189070-58194053 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 4 "Sertoli cells: 3.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 65: Non-specific - Cell growth & division" ORAI1 "CRACM1, FLJ14466, TMEM142A" ENSG00000276045 "ORAI calcium release-activated calcium modulator 1" Q96D31 12 121626509-121643218 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Adaptive immunity, Calcium transport, Immunity, Ion transport, Transport" "Calcium channel, Calmodulin-binding, Ion channel" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 63.1;skeletal muscle: 57.2" "Cell type enhanced" "Detected in some" "Bergmann glia: 2.4;Choroid plexus epithelial cells: 10.3;Loop of henle epithelial cells: 2.4;Microglia: 6.4;NK-cells: 3.3;Oligodendrocyte progenitor cells: 5.9;Oligodendrocytes: 2.6;Papillary tip epithelial cells: 4.2;Platelets: 2.8;Proximal tubule cells: 2.4;Renal collecting duct intercalated cells: 5.8;Renal collecting duct principal cells: 3.7;Renal connecting tubule cells: 3.0" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 18.1;endothelial cell: 34.7;leukocyte: 36.6" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "choroid plexus: 41.9" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Pituitary gland - Endothelial cells, Skeletal muscle - Skeletal myocytes, Skin - Keratinocyte (other), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016583 Approved NA NA "Cluster 27: T-cells - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 102: Non-specific - Mixed function" 8 "HPA016583: " "unprognostic (2.50e-1)" "unprognostic (1.82e-1)" "unprognostic (2.46e-1)" "unprognostic (9.15e-2)" "unprognostic (2.60e-1)" "unprognostic (1.31e-1)" "unprognostic (7.73e-2)" "unprognostic (2.97e-3)" "unprognostic (2.66e-1)" "unprognostic (1.84e-3)" "unprognostic (1.44e-1)" "unprognostic (4.78e-3)" "unprognostic (5.00e-3)" "unprognostic (1.13e-1)" "unprognostic (2.06e-2)" "unprognostic (3.42e-1)" "unprognostic (3.07e-1)" "unprognostic (4.75e-1)" "unprognostic (2.24e-1)" "unprognostic (3.07e-1)" "unprognostic (3.38e-1)" "unprognostic (1.37e-1)" "unprognostic (4.26e-1)" "unprognostic (6.49e-3)" "unprognostic (1.94e-1)" "unprognostic (2.12e-1)" "unprognostic (1.53e-1)" "unprognostic (2.57e-1)" ORAI2 "C7orf19, CBCIP2, FLJ12474, FLJ14733, H_NH0514P08.8, TMEM142B" ENSG00000160991 "ORAI calcium release-activated calcium modulator 2" Q96SN7 7 102433106-102456825 "Predicted intracellular proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "B-cells: 132.7;Endometrial luminal cells: 158.9;Neutrophil progenitors: 241.1;Neutrophils: 290.1;Platelets: 339.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 7.0;eosinophil: 24.9;memory B-cell: 10.2;naive B-cell: 11.4;neutrophil: 27.7;NK-cell: 8.3" "Group enriched" "Detected in all" 5 "B-cells: 11.4;granulocytes: 27.7;NK-cells: 8.3" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells, Skeletal muscle - Endothelial cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065937, HPA074525" Uncertain Supported Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 29: Forebrain - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 48: Neutrophils - Phagocytosis & degranulation" "Nucleoplasm, Mitochondria" Cytosol "HPA065937: , HPA074525: " "potential prognostic favorable (7.25e-4)" "unprognostic (9.22e-3)" "unprognostic (3.16e-3)" "unprognostic (4.00e-3)" "unprognostic (8.60e-2)" "unprognostic (3.02e-1)" "unprognostic (2.80e-2)" "unprognostic (7.12e-2)" "unprognostic (6.09e-2)" "unprognostic (2.96e-2)" "unprognostic (5.29e-2)" "unprognostic (4.04e-2)" "unprognostic (1.54e-1)" "unprognostic (3.68e-2)" "unprognostic (1.76e-2)" "unprognostic (3.08e-1)" "unprognostic (4.93e-2)" "unprognostic (1.41e-2)" "unprognostic (2.87e-1)" "unprognostic (2.40e-2)" "unprognostic (2.04e-3)" "unprognostic (4.62e-3)" "unprognostic (3.58e-2)" "unprognostic (2.42e-1)" "unprognostic (1.50e-1)" "unprognostic (2.65e-2)" "unprognostic (1.81e-1)" "unprognostic (6.71e-2)" "unprognostic (1.75e-1)" "unprognostic (2.69e-2)" "unprognostic (1.59e-1)" ORAI3 "MGC13024, TMEM142C" ENSG00000175938 "ORAI calcium release-activated calcium modulator 3" Q9BRQ5 16 30949068-30956461 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Hofbauer cells: 8.8;Leydig cells: 4.6;Megakaryocytes: 6.2;Melanocytes: 4.3;Papillary tip epithelial cells: 6.7;Podocytes: 8.5;Proximal tubule cells: 4.8;Respiratory ionocytes: 5.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015022 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 38: Sub-cortical - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 1 "Nucleoplasm, Cytosol" "HPA015022: " "unprognostic (1.55e-1)" "unprognostic (1.92e-1)" "unprognostic (3.96e-1)" "unprognostic (2.27e-1)" "unprognostic (1.83e-2)" "unprognostic (2.58e-2)" "unprognostic (1.44e-2)" "unprognostic (4.76e-1)" "unprognostic (1.93e-1)" "unprognostic (2.69e-1)" "unprognostic (1.14e-2)" "unprognostic (2.15e-2)" "unprognostic (1.32e-1)" "unprognostic (8.52e-2)" "unprognostic (3.20e-1)" "unprognostic (9.05e-2)" "unprognostic (1.69e-1)" "unprognostic (6.16e-2)" "unprognostic (1.99e-1)" "unprognostic (9.35e-2)" "unprognostic (6.90e-2)" "unprognostic (1.66e-1)" "unprognostic (4.09e-2)" "unprognostic (5.88e-2)" "unprognostic (6.15e-3)" "unprognostic (2.88e-1)" "unprognostic (3.11e-2)" "unprognostic (6.45e-3)" "unprognostic (2.13e-2)" "unprognostic (6.35e-2)" "unprognostic (1.69e-2)" ORC1 "HSORC1, ORC1L, PARC1" ENSG00000085840 "Origin recognition complex subunit 1" Q13415 1 52372829-52404423 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "DNA replication" DNA-binding "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 27.4;lymphoid tissue: 10.8" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 73.0;Extravillous trophoblasts: 13.1;Megakaryocyte progenitors: 23.5;Monocyte progenitors: 37.6;Neutrophil progenitors: 30.1" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 22.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 3.4" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA027439, HPA027450" Uncertain Supported Nucleoplasm NA Yes "Cluster 33: Non-specific - ATP binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 48: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 31 Nucleoplasm "HPA027439: , HPA027450: " "unprognostic (1.65e-2)" "unprognostic (1.68e-1)" "unprognostic (1.46e-2)" "potential prognostic favorable (2.05e-4)" "unprognostic (1.36e-1)" "unprognostic (1.21e-1)" "unprognostic (1.29e-3)" "unprognostic (1.69e-2)" "unprognostic (1.18e-2)" "potential prognostic unfavorable (4.73e-5)" "potential prognostic unfavorable (1.33e-4)" "validated prognostic unfavorable (7.35e-6)" "validated prognostic unfavorable (1.56e-5)" "potential prognostic unfavorable (5.93e-4)" "unprognostic (2.07e-3)" "unprognostic (1.44e-2)" "unprognostic (1.91e-2)" "unprognostic (1.04e-1)" "unprognostic (2.38e-2)" "potential prognostic unfavorable (4.99e-4)" "unprognostic (2.59e-1)" "potential prognostic favorable (4.29e-4)" "unprognostic (5.98e-3)" "unprognostic (1.38e-3)" "unprognostic (2.90e-2)" "unprognostic (1.09e-1)" "unprognostic (2.02e-1)" ORC2 ORC2L ENSG00000115942 "Origin recognition complex subunit 2" Q13416 2 200908977-200963680 "Essential proteins, Predicted intracellular proteins" "DNA replication" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 250.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003693, HPA073881" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 39: Testis - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 24: Neutrophils - Innate immunity signal integration" 47 Nucleoplasm Cytosol "CAB003693: , HPA073881: " "unprognostic (3.07e-2)" "unprognostic (2.80e-2)" "unprognostic (1.93e-1)" "unprognostic (2.44e-1)" "unprognostic (2.05e-1)" "unprognostic (3.64e-1)" "unprognostic (4.19e-2)" "unprognostic (1.24e-1)" "potential prognostic unfavorable (9.68e-4)" "unprognostic (8.25e-3)" "unprognostic (1.31e-2)" "unprognostic (3.11e-1)" "unprognostic (2.63e-3)" "unprognostic (2.21e-2)" "unprognostic (6.92e-3)" "unprognostic (7.51e-2)" "unprognostic (1.14e-2)" "unprognostic (4.46e-3)" "unprognostic (2.45e-1)" "unprognostic (2.49e-1)" "unprognostic (1.42e-2)" "unprognostic (4.37e-2)" "unprognostic (1.84e-2)" "unprognostic (1.27e-2)" "unprognostic (5.08e-2)" "unprognostic (2.06e-2)" "unprognostic (3.42e-2)" "unprognostic (3.97e-1)" "unprognostic (6.28e-2)" "unprognostic (1.18e-1)" ORC3 "IMAGE50150, LATHEO, ORC3L" ENSG00000135336 "Origin recognition complex subunit 3" Q9UBD5 6 87590067-87667453 "Essential proteins, Predicted intracellular proteins, Predicted membrane proteins" "DNA replication" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039553, HPA053748" Enhanced Supported Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" 21 Nucleoplasm "HPA039553: , HPA053748: " "unprognostic (6.26e-2)" "unprognostic (9.42e-3)" "unprognostic (4.14e-1)" "unprognostic (1.49e-1)" "unprognostic (2.59e-1)" "unprognostic (8.45e-2)" "unprognostic (4.17e-1)" "unprognostic (2.64e-1)" "unprognostic (1.55e-2)" "unprognostic (1.89e-2)" "unprognostic (2.87e-3)" "unprognostic (1.23e-2)" "unprognostic (1.98e-2)" "unprognostic (2.10e-1)" "unprognostic (4.29e-2)" "unprognostic (2.47e-1)" "unprognostic (3.99e-2)" "unprognostic (4.34e-2)" "unprognostic (2.74e-2)" "unprognostic (3.63e-2)" "unprognostic (2.56e-1)" "unprognostic (3.95e-3)" "unprognostic (1.00e-1)" "potential prognostic favorable (1.22e-5)" "unprognostic (1.23e-3)" "unprognostic (4.52e-2)" "unprognostic (7.19e-2)" "unprognostic (2.00e-2)" "unprognostic (6.89e-2)" "unprognostic (1.74e-3)" ORC4 "HsORC4, ORC4L, Orc4p" ENSG00000115947 "Origin recognition complex subunit 4" O43929 2 147930396-148021604 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "DNA replication" DNA-binding "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 344.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015124, HPA064562" Approved Supported Nucleoplasm,Nucleoli NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 2: Neurons - Nucleosome" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 39 "Nucleoplasm, Nucleoli" "CAB015124: , HPA064562: " "unprognostic (7.62e-2)" "unprognostic (3.01e-3)" "unprognostic (1.48e-1)" "unprognostic (3.20e-1)" "unprognostic (1.04e-1)" "unprognostic (5.23e-2)" "unprognostic (6.12e-2)" "unprognostic (2.98e-1)" "unprognostic (4.56e-3)" "potential prognostic favorable (5.60e-9)" "unprognostic (5.83e-3)" "unprognostic (1.08e-1)" "potential prognostic unfavorable (9.72e-4)" "unprognostic (2.23e-2)" "unprognostic (3.82e-1)" "unprognostic (1.88e-1)" "unprognostic (2.29e-1)" "unprognostic (1.60e-2)" "unprognostic (3.12e-1)" "unprognostic (8.63e-2)" "validated prognostic unfavorable (5.86e-4)" "validated prognostic unfavorable (1.65e-4)" "unprognostic (1.76e-1)" "potential prognostic favorable (2.48e-5)" "unprognostic (8.05e-3)" "unprognostic (4.61e-2)" "unprognostic (5.53e-2)" "unprognostic (2.04e-1)" "unprognostic (5.15e-2)" "unprognostic (5.68e-2)" ORC5 "ORC5L, Orc5p, ORC5T, PPP1R117" ENSG00000164815 "Origin recognition complex subunit 5" O43913 7 104126341-104208047 "Essential proteins, Predicted intracellular proteins" "DNA replication" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 128.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019730 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 57: Testis - Spermatogenesis" "Cluster 31: Non-specific - Transcription" "Cluster 39: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 20 Nucleoplasm Cytosol "HPA019730: " "unprognostic (2.42e-1)" "unprognostic (1.11e-2)" "unprognostic (3.74e-2)" "unprognostic (3.42e-1)" "unprognostic (1.60e-1)" "unprognostic (4.30e-2)" "unprognostic (2.52e-1)" "unprognostic (3.63e-2)" "unprognostic (9.55e-3)" "unprognostic (2.50e-3)" "unprognostic (2.98e-1)" "unprognostic (3.24e-1)" "potential prognostic unfavorable (1.10e-4)" "unprognostic (1.01e-3)" "unprognostic (3.57e-2)" "unprognostic (2.62e-2)" "unprognostic (1.24e-2)" "unprognostic (3.32e-1)" "unprognostic (1.04e-1)" "unprognostic (1.23e-1)" "unprognostic (9.52e-2)" "unprognostic (1.65e-2)" "unprognostic (1.43e-1)" "unprognostic (1.42e-1)" "unprognostic (1.43e-1)" "unprognostic (2.69e-2)" "unprognostic (2.16e-1)" "unprognostic (8.39e-2)" "unprognostic (1.66e-2)" "unprognostic (2.48e-1)" ORC6 ORC6L ENSG00000091651 "Origin recognition complex subunit 6" Q9Y5N6 16 46689643-46698394 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "DNA replication" DNA-binding "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 9.7;lymphoid tissue: 6.9;testis: 9.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 45.5;Differentiating spermatogonia: 91.2;Early primary spermatocytes: 154.4;Erythrocyte progenitors: 86.7;Esophageal basal cells: 36.6;Extravillous trophoblasts: 40.9;Megakaryocyte progenitors: 67.6;Migrating cytotrophoblasts: 53.2;Monocyte progenitors: 39.3;Sertoli cells: 39.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016330, HPA072587" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center" Yes No "Cluster 16: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 14: Neurons - Synaptic function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 27: Non-specific - Cell proliferation" 16 "Nucleoplasm, Nucleoli fibrillar center" "CAB016330: , HPA072587: " "unprognostic (1.02e-3)" "unprognostic (1.26e-2)" "unprognostic (9.28e-3)" "unprognostic (1.89e-1)" "unprognostic (1.71e-1)" "unprognostic (1.54e-2)" "unprognostic (4.00e-3)" "unprognostic (4.58e-3)" "unprognostic (3.69e-1)" "validated prognostic unfavorable (4.56e-6)" "validated prognostic unfavorable (5.40e-6)" "potential prognostic unfavorable (1.54e-7)" "validated prognostic unfavorable (2.22e-8)" "validated prognostic unfavorable (7.03e-6)" "potential prognostic unfavorable (3.39e-5)" "unprognostic (2.02e-3)" "unprognostic (2.01e-1)" "unprognostic (1.84e-2)" "unprognostic (4.57e-2)" "unprognostic (1.76e-1)" "validated prognostic unfavorable (7.66e-4)" "validated prognostic unfavorable (8.00e-5)" "unprognostic (2.70e-2)" "unprognostic (2.40e-1)" "unprognostic (5.08e-2)" "unprognostic (9.08e-3)" "unprognostic (3.91e-1)" "unprognostic (3.97e-1)" "unprognostic (3.75e-3)" "unprognostic (6.67e-2)" ORM1 ENSG00000229314 "Orosomucoid 1" P02763 9 114323098-114326479 "Cancer-related genes, Candidate cardiovascular disease genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Acute phase, Transport" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 187 "liver: 42168.4" "Cell type enriched" "Detected in some" 60 "Hepatocytes: 63160.9" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 13 "Liver Hepatocellular Carcinoma (TCGA): 7670.7" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in some" 47 "neutrophil: 201.8" "Lineage enriched" "Detected in many" 47 "granulocytes: 201.8" "Cancer enriched" "Detected in many" 4 "liver cancer: 243.4" "Liver - Hepatocytes, Lung - Neutrophils_2" "CAB006265, HPA046438, HPA047725, HPA057726" Approved Approved "Golgi apparatus,Vesicles" "Secreted to blood" "Acute phase" NA NA 945000000000 66000000000 "Cluster 4: Neutrophils - Degranulation" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 54: Immune cells - T cell receptor" "Cluster 18: Liver cancer - Metabolism" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 22 Vesicles "Golgi apparatus" "CAB006265: , HPA046438: , HPA047725: , HPA057726: " "unprognostic (3.25e-1)" "unprognostic (4.14e-2)" "unprognostic (1.24e-1)" "unprognostic (3.16e-3)" "unprognostic (9.91e-3)" "unprognostic (1.59e-2)" "unprognostic (1.86e-2)" "unprognostic (2.66e-1)" "potential prognostic favorable (1.16e-4)" "unprognostic (6.02e-2)" "unprognostic (1.88e-1)" "unprognostic (3.33e-2)" "unprognostic (1.94e-1)" "unprognostic (1.82e-1)" "unprognostic (1.22e-1)" "unprognostic (2.59e-3)" "unprognostic (3.24e-2)" "unprognostic (1.77e-1)" "unprognostic (1.13e-1)" "unprognostic (1.25e-1)" "unprognostic (6.24e-1)" "unprognostic (1.47e-1)" "unprognostic (1.98e-2)" "unprognostic (1.20e-2)" "unprognostic (9.18e-2)" ORM2 "AGP-B, AGP-B', AGP2" ENSG00000228278 "Orosomucoid 2" P19652 9 114329869-114333251 "FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Acute phase, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 295 "liver: 8192.9" "Cell type enriched" "Detected in some" 49 "Hepatocytes: 12409.0" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 33 "Liver Hepatocellular Carcinoma (TCGA): 2268.7" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 39 "neutrophil: 13.2" "Lineage enriched" "Detected in single" 39 "granulocytes: 13.2" "Cancer enriched" "Detected in some" 27 "liver cancer: 95.6" "Liver - Hepatocytes, Testis - Late spermatids" "HPA046438, HPA047725, HPA057726" Approved Approved "Golgi apparatus,Vesicles" "Secreted to blood" "Acute phase" NA NA 422000000 36000000000 "Cluster 4: Neutrophils - Degranulation" "Cluster 53: Liver - Plasma proteins" "Cluster 33: Neurons - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 5 Vesicles "Golgi apparatus" "HPA046438: , HPA047725: , HPA057726: " "unprognostic (2.88e-3)" "unprognostic (3.41e-1)" "potential prognostic unfavorable (5.27e-6)" "unprognostic (6.53e-2)" "unprognostic (8.21e-3)" "unprognostic (9.83e-2)" "unprognostic (4.84e-3)" "unprognostic (1.47e-2)" "unprognostic (1.04e-1)" "unprognostic (1.81e-1)" "unprognostic (6.38e-3)" "unprognostic (5.16e-1)" "unprognostic (5.21e-2)" "unprognostic (1.09e-1)" "unprognostic (6.66e-1)" "unprognostic (3.28e-1)" "unprognostic (5.20e-1)" ORMDL1 ENSG00000128699 "ORMDL sphingolipid biosynthesis regulator 1" Q9P0S3 2 189770267-189784364 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065643 Supported "Endoplasmic reticulum" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 49: Non-specific - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 56: Non-specific - Sensory perception" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 33 "Endoplasmic reticulum" "HPA065643: " "unprognostic (1.83e-2)" "unprognostic (9.30e-3)" "unprognostic (1.16e-2)" "unprognostic (8.50e-2)" "unprognostic (1.99e-2)" "unprognostic (3.33e-1)" "unprognostic (2.51e-1)" "unprognostic (3.16e-2)" "unprognostic (8.95e-2)" "unprognostic (4.49e-2)" "unprognostic (4.89e-2)" "unprognostic (3.17e-1)" "unprognostic (1.48e-1)" "unprognostic (1.38e-3)" "unprognostic (4.46e-2)" "unprognostic (2.12e-2)" "unprognostic (1.58e-1)" "unprognostic (2.53e-1)" "unprognostic (2.72e-2)" "unprognostic (6.80e-2)" "unprognostic (1.30e-2)" "unprognostic (1.34e-2)" "unprognostic (8.54e-3)" "unprognostic (3.21e-2)" "unprognostic (1.88e-2)" "unprognostic (3.29e-2)" "unprognostic (1.30e-2)" "unprognostic (1.04e-1)" "unprognostic (2.83e-1)" "unprognostic (1.74e-1)" "unprognostic (1.81e-1)" ORMDL2 "adoplin-2, HSPC160, MST095, MSTP095" ENSG00000123353 "ORMDL sphingolipid biosynthesis regulator 2" Q53FV1 12 55818041-55821879 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 805.3;Esophageal suprabasal cells: 281.7;Late primary spermatocytes: 215.4;Syncytiotrophoblasts: 189.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Macrophages, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065643 Supported "Endoplasmic reticulum" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 85: Squamous epithelial cells - Keratinization" 20 "Endoplasmic reticulum" "HPA065643: " "unprognostic (1.19e-1)" "unprognostic (7.57e-3)" "unprognostic (9.55e-2)" "unprognostic (9.91e-2)" "unprognostic (1.99e-2)" "unprognostic (2.22e-1)" "unprognostic (2.33e-3)" "unprognostic (3.96e-1)" "potential prognostic unfavorable (4.58e-4)" "unprognostic (3.91e-3)" "unprognostic (1.09e-1)" "unprognostic (4.71e-3)" "unprognostic (4.60e-2)" "validated prognostic unfavorable (5.07e-4)" "validated prognostic unfavorable (8.60e-6)" "unprognostic (8.94e-3)" "unprognostic (1.53e-1)" "unprognostic (3.32e-1)" "unprognostic (2.30e-2)" "unprognostic (2.08e-1)" "unprognostic (1.89e-1)" "unprognostic (4.53e-3)" "unprognostic (9.56e-2)" "unprognostic (1.98e-1)" "unprognostic (4.45e-1)" "unprognostic (5.93e-1)" "unprognostic (1.84e-2)" "unprognostic (1.89e-2)" "unprognostic (1.69e-1)" "unprognostic (8.86e-2)" "unprognostic (3.50e-1)" ORMDL3 ENSG00000172057 "ORMDL sphingolipid biosynthesis regulator 3" Q8N138 17 39921041-39927601 "Disease related genes, Predicted membrane proteins" Asthma "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 225.6" "Cell type enhanced" "Detected in many" "Early spermatids: 319.0;Hepatocytes: 112.1;Late spermatids: 536.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Pituitary gland - Gonadotropes, Prostate - Prostate glandular cells, Skin - Inner root sheath cells, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065643 Supported "Endoplasmic reticulum" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 23: Choroid plexus - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 26 "Endoplasmic reticulum" "HPA065643: " "unprognostic (7.80e-3)" "unprognostic (3.11e-2)" "unprognostic (1.71e-2)" "unprognostic (4.06e-1)" "unprognostic (3.64e-1)" "unprognostic (2.49e-1)" "unprognostic (4.61e-2)" "unprognostic (7.64e-2)" "unprognostic (2.48e-1)" "unprognostic (9.72e-2)" "unprognostic (1.06e-1)" "unprognostic (1.39e-1)" "unprognostic (3.10e-1)" "unprognostic (1.32e-1)" "unprognostic (1.42e-1)" "unprognostic (1.59e-3)" "unprognostic (2.24e-1)" "unprognostic (1.80e-1)" "unprognostic (6.36e-3)" "unprognostic (2.38e-1)" "unprognostic (8.34e-2)" "unprognostic (8.87e-2)" "unprognostic (1.81e-1)" "unprognostic (1.02e-1)" "unprognostic (1.42e-1)" "unprognostic (7.17e-3)" "unprognostic (7.15e-2)" "unprognostic (1.78e-1)" "unprognostic (1.51e-2)" "unprognostic (3.28e-3)" "unprognostic (6.98e-2)" OS9 "ERLEC2, OS-9" ENSG00000135506 "OS9 endoplasmic reticulum lectin" Q13438 12 57693841-57728342 "Essential proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Colon - Macrophages, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Skin - Fibroblasts_2, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011518, HPA013694" Supported Supported "Endoplasmic reticulum" "Intracellular and membrane" "No annotated function" NA NA 41000 "Cluster 29: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 44: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 78: Plasma cells - Antibody production & ER-stress response" 45 "Endoplasmic reticulum" "CAB011518: , HPA013694: " "unprognostic (2.50e-1)" "unprognostic (2.47e-3)" "unprognostic (1.51e-1)" "unprognostic (2.67e-2)" "unprognostic (8.21e-2)" "unprognostic (1.16e-2)" "unprognostic (2.65e-2)" "unprognostic (1.69e-1)" "unprognostic (4.94e-2)" "unprognostic (3.69e-2)" "potential prognostic favorable (1.02e-7)" "unprognostic (2.14e-1)" "unprognostic (4.72e-1)" "unprognostic (9.09e-2)" "unprognostic (1.07e-2)" "unprognostic (2.36e-1)" "unprognostic (1.52e-1)" "unprognostic (1.45e-1)" "unprognostic (5.97e-2)" "unprognostic (2.38e-1)" "unprognostic (6.80e-3)" "unprognostic (3.33e-2)" "unprognostic (3.05e-1)" "unprognostic (4.42e-1)" "unprognostic (7.89e-2)" "unprognostic (2.14e-1)" "unprognostic (2.30e-1)" "unprognostic (1.24e-1)" "unprognostic (1.47e-1)" "unprognostic (5.50e-2)" "unprognostic (2.42e-1)" OSBP OSBP1 ENSG00000110048 "Oxysterol binding protein" P22059 11 59574398-59615774 "Essential proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039227, HPA043625" Enhanced Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 34000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 24: Non-specific - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 41 "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA039227: , HPA043625: " "unprognostic (1.40e-1)" "unprognostic (1.82e-2)" "unprognostic (2.47e-1)" "unprognostic (2.22e-2)" "unprognostic (3.54e-2)" "unprognostic (2.49e-1)" "unprognostic (9.54e-2)" "unprognostic (3.13e-1)" "unprognostic (8.84e-2)" "unprognostic (8.62e-3)" "potential prognostic favorable (3.40e-8)" "unprognostic (1.70e-3)" "unprognostic (3.03e-1)" "unprognostic (3.67e-1)" "unprognostic (6.27e-2)" "unprognostic (2.94e-2)" "unprognostic (3.78e-2)" "unprognostic (2.98e-2)" "unprognostic (1.53e-1)" "unprognostic (8.64e-2)" "unprognostic (1.43e-2)" "potential prognostic unfavorable (3.99e-4)" "unprognostic (2.89e-1)" "unprognostic (3.69e-2)" "unprognostic (1.79e-2)" "unprognostic (2.28e-3)" "unprognostic (7.77e-2)" "unprognostic (1.09e-1)" "unprognostic (5.83e-2)" "unprognostic (1.94e-1)" "unprognostic (1.46e-1)" OSBP2 "KIAA1664, ORP-4, ORP4, OSBPL1" ENSG00000184792 "Oxysterol binding protein 2" Q969R2 22 30693782-30907824 "Predicted intracellular proteins" "Differentiation, Lipid transport, Spermatogenesis, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 49.6;retina: 149.3" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 242.3;Early spermatids: 324.1;Late spermatids: 613.6;Oligodendrocytes: 283.4;Retinal amacrine cells: 230.5;Retinal bipolar cells: 258.3;Rod photoreceptor cells: 1448.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "cervical cancer: 54.3" "Heart muscle - Cardiomyocytes, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Lactotropes, Spleen - Erythrocytes, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021514 Uncertain Approved Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 37: Neurons - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" 9 Cytosol "HPA021514: " "unprognostic (3.06e-1)" "unprognostic (1.56e-1)" "unprognostic (1.14e-1)" "unprognostic (1.03e-1)" "unprognostic (1.18e-1)" "unprognostic (2.67e-1)" "unprognostic (2.84e-1)" "unprognostic (1.87e-1)" "unprognostic (1.77e-1)" "unprognostic (1.32e-3)" "potential prognostic favorable (2.57e-5)" "unprognostic (3.01e-3)" "unprognostic (1.71e-1)" "potential prognostic unfavorable (9.14e-5)" "unprognostic (1.06e-2)" "unprognostic (2.00e-1)" "unprognostic (1.30e-1)" "unprognostic (1.45e-1)" "potential prognostic favorable (6.41e-4)" "unprognostic (1.16e-1)" "unprognostic (1.10e-2)" "unprognostic (3.53e-1)" "unprognostic (7.33e-3)" "unprognostic (1.83e-1)" "unprognostic (1.52e-1)" "unprognostic (1.72e-1)" "unprognostic (7.04e-2)" "unprognostic (1.21e-1)" "unprognostic (1.60e-1)" "unprognostic (1.30e-1)" "unprognostic (8.55e-2)" OSBPL10 ENSG00000144645 "Oxysterol binding protein like 10" Q9BXB5 3 31657912-32077580 "Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 723.7;Corticotrophs: 513.4;Early spermatids: 655.6;Endometrial glandular cells: 505.9;Endometrial luminal cells: 484.3;Late spermatids: 1990.4;Pituitary stem cells: 891.5;Proximal tubule cells: 499.2;Sertoli cells: 649.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 17 "memory B-cell: 11.5;naive B-cell: 6.8" "Lineage enriched" "Detected in single" 22 "B-cells: 11.5" "Low cancer specificity" "Detected in many" "Prostate - Smooth muscle cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003636 Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 53: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 12 "Golgi apparatus, Plasma membrane" Nucleoplasm "HPA003636: " "unprognostic (2.27e-2)" "unprognostic (1.21e-2)" "unprognostic (2.34e-1)" "unprognostic (1.09e-2)" "unprognostic (3.03e-1)" "potential prognostic unfavorable (3.39e-4)" "unprognostic (3.07e-1)" "potential prognostic unfavorable (1.80e-4)" "unprognostic (2.41e-1)" "unprognostic (5.86e-2)" "potential prognostic favorable (1.41e-5)" "unprognostic (5.81e-2)" "unprognostic (3.58e-3)" "unprognostic (6.77e-2)" "unprognostic (5.06e-2)" "unprognostic (5.72e-2)" "potential prognostic unfavorable (3.88e-4)" "unprognostic (2.35e-1)" "unprognostic (2.35e-2)" "unprognostic (1.40e-2)" "potential prognostic unfavorable (8.08e-4)" "potential prognostic unfavorable (2.08e-4)" "unprognostic (9.99e-2)" "unprognostic (3.49e-1)" "unprognostic (5.44e-2)" "potential prognostic favorable (4.21e-4)" "unprognostic (4.72e-2)" "unprognostic (1.59e-1)" "unprognostic (3.52e-1)" "unprognostic (2.33e-2)" "unprognostic (1.55e-1)" OSBPL11 "FLJ13012, FLJ13164, ORP-11, ORP11" ENSG00000144909 "Oxysterol binding protein like 11" Q9BXB4 3 125528858-125595497 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 51.5;tongue: 74.8" "Cell type enhanced" "Detected in many" "Astrocytes: 157.0;Kupffer cells: 198.8;Microglia: 185.9;Myonuclei: 255.1;Neutrophils: 242.4;Sertoli cells: 161.1" "Cell type enhanced" "Detected in all" "astrocyte: 230.7;central nervous system macrophage: 228.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin), Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039144 Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 24: Neutrophils - Innate immunity signal integration" 14 "Nucleoplasm, Golgi apparatus" "HPA039144: " "unprognostic (1.44e-1)" "unprognostic (2.77e-2)" "unprognostic (4.26e-1)" "unprognostic (1.90e-1)" "unprognostic (8.00e-2)" "unprognostic (1.89e-1)" "unprognostic (4.88e-2)" "unprognostic (2.45e-1)" "unprognostic (7.50e-3)" "unprognostic (2.21e-3)" "potential prognostic favorable (7.09e-6)" "unprognostic (1.25e-1)" "unprognostic (1.20e-1)" "unprognostic (1.08e-1)" "unprognostic (2.31e-2)" "unprognostic (6.50e-2)" "unprognostic (9.40e-2)" "unprognostic (3.46e-2)" "unprognostic (6.91e-2)" "unprognostic (9.86e-2)" "unprognostic (2.41e-2)" "unprognostic (2.91e-2)" "unprognostic (5.62e-2)" "unprognostic (3.68e-2)" "unprognostic (9.74e-2)" "unprognostic (4.35e-2)" "unprognostic (1.16e-1)" "unprognostic (1.84e-1)" "unprognostic (6.88e-2)" "unprognostic (2.33e-2)" "unprognostic (1.87e-3)" OSBPL1A "ORP-1, ORP1, OSBPL1B" ENSG00000141447 "Oxysterol binding protein like 1A" Q9BXW6 18 24162045-24397880 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 644.8;Oligodendrocytes: 657.7;Retinal pigment epithelial cells: 643.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 22 "basophil: 93.6" "Lineage enriched" "Detected in many" 22 "granulocytes: 93.6" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040959, HPA043401" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 14 "Nucleoplasm, Cytosol" "HPA040959: , HPA043401: " "unprognostic (6.07e-2)" "unprognostic (4.76e-2)" "unprognostic (8.63e-2)" "unprognostic (8.38e-3)" "unprognostic (1.09e-1)" "unprognostic (3.46e-2)" "unprognostic (1.70e-1)" "potential prognostic unfavorable (9.22e-4)" "unprognostic (1.32e-1)" "unprognostic (4.82e-3)" "validated prognostic favorable (5.61e-10)" "validated prognostic favorable (6.63e-7)" "unprognostic (4.72e-3)" "unprognostic (7.34e-2)" "unprognostic (2.30e-3)" "unprognostic (2.87e-1)" "unprognostic (1.97e-2)" "unprognostic (3.18e-2)" "unprognostic (3.94e-1)" "unprognostic (3.90e-1)" "unprognostic (1.39e-1)" "unprognostic (8.05e-2)" "unprognostic (2.70e-1)" "unprognostic (2.86e-1)" "unprognostic (1.95e-1)" "unprognostic (9.42e-2)" "unprognostic (2.14e-1)" "potential prognostic unfavorable (3.48e-4)" "unprognostic (3.58e-2)" "unprognostic (5.07e-3)" "unprognostic (3.79e-1)" OSBPL2 "DFNA67, KIAA0772, ORP-2" ENSG00000130703 "Oxysterol binding protein like 2" Q9H1P3 20 62231922-62296213 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Lipid transport, Transport" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 289.1;Neutrophils: 257.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 94.9" "Lineage enriched" "Detected in all" 5 "granulocytes: 94.9" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary gland basal cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041127, HPA042659" Uncertain Approved Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 64: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 7: Liver cancer - Metabolism" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 8 Cytosol "HPA041127: , HPA042659: " "unprognostic (2.14e-1)" "potential prognostic unfavorable (1.53e-4)" "unprognostic (2.99e-1)" "unprognostic (7.74e-2)" "unprognostic (3.71e-1)" "unprognostic (6.16e-2)" "unprognostic (1.93e-1)" "unprognostic (2.59e-2)" "unprognostic (2.90e-2)" "unprognostic (2.20e-1)" "potential prognostic favorable (2.40e-7)" "unprognostic (2.10e-3)" "unprognostic (1.19e-2)" "unprognostic (1.04e-3)" "unprognostic (2.69e-1)" "unprognostic (2.67e-2)" "unprognostic (2.69e-1)" "unprognostic (9.67e-3)" "unprognostic (1.13e-1)" "unprognostic (1.07e-1)" "unprognostic (1.82e-1)" "unprognostic (1.40e-1)" "unprognostic (2.10e-1)" "unprognostic (1.52e-1)" "unprognostic (4.83e-3)" "unprognostic (3.58e-3)" "unprognostic (2.05e-1)" "unprognostic (1.48e-1)" "unprognostic (1.21e-1)" "unprognostic (9.36e-2)" "unprognostic (3.60e-2)" OSBPL3 "KIAA0704, ORP-3, ORP3, OSBP3" ENSG00000070882 "Oxysterol binding protein like 3" Q9H4L5 7 24796540-24981634 "Plasma proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 602.4;Endometrial ciliated cells: 336.4;Endometrial luminal cells: 309.4;Loop of henle epithelial cells: 471.4;Plasma cells: 481.0;Renal collecting duct intercalated cells: 442.5;Renal connecting tubule cells: 317.4;Respiratory ciliated cells: 307.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Urothelial cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000691, HPA048401" Enhanced Supported Nucleoli,Cytosol NA Yes "Cluster 42: Non-specific - Vesicular transport" "Cluster 72: Kidney - Transmembrane transport" "Cluster 53: Neurons - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 78: Plasma cells - Antibody production & ER-stress response" 48 Cytosol Nucleoli "HPA000691: , HPA048401: " "unprognostic (1.21e-1)" "unprognostic (4.42e-1)" "unprognostic (4.56e-2)" "unprognostic (6.83e-3)" "unprognostic (3.49e-3)" "unprognostic (3.39e-2)" "unprognostic (2.49e-1)" "unprognostic (5.52e-3)" "unprognostic (2.36e-1)" "unprognostic (4.64e-2)" "unprognostic (2.99e-1)" "unprognostic (1.90e-1)" "unprognostic (9.88e-2)" "potential prognostic unfavorable (6.93e-4)" "unprognostic (1.09e-1)" "unprognostic (9.88e-3)" "unprognostic (9.00e-3)" "unprognostic (1.83e-1)" "unprognostic (1.66e-1)" "unprognostic (1.10e-1)" "unprognostic (4.28e-2)" "potential prognostic unfavorable (6.01e-4)" "unprognostic (2.96e-2)" "unprognostic (3.29e-1)" "unprognostic (1.44e-1)" "unprognostic (3.03e-1)" "unprognostic (8.09e-2)" "unprognostic (2.86e-2)" "unprognostic (3.42e-1)" "unprognostic (9.49e-3)" OSBPL5 "KIAA1534, OBPH1, ORP5" ENSG00000021762 "Oxysterol binding protein like 5" Q9H0X9 11 3087107-3166739 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 97.3;NK-cells: 165.0;Retinal horizontal cells: 160.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 3.6;gdT-cell: 9.0;intermediate monocyte: 4.7;memory CD8 T-cell: 3.3;myeloid DC: 3.0;naive CD8 T-cell: 3.4;NK-cell: 11.0;non-classical monocyte: 11.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038335, HPA038712, HPA058727" Approved Enhanced Vesicles NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 74: Non-specific - Signal transduction" "Cluster 49: Hindbrain - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 7 Vesicles "HPA038335: , HPA038712: , HPA058727: " "unprognostic (7.53e-2)" "unprognostic (5.91e-2)" "unprognostic (1.11e-1)" "unprognostic (2.76e-2)" "unprognostic (4.01e-2)" "unprognostic (2.48e-2)" "unprognostic (5.04e-3)" "unprognostic (1.31e-1)" "unprognostic (1.65e-1)" "unprognostic (4.83e-2)" "unprognostic (2.21e-1)" "unprognostic (2.41e-1)" "unprognostic (3.76e-2)" "unprognostic (8.63e-2)" "potential prognostic favorable (1.64e-4)" "unprognostic (2.51e-2)" "unprognostic (3.91e-2)" "unprognostic (2.88e-3)" "unprognostic (1.77e-1)" "unprognostic (1.88e-2)" "unprognostic (2.82e-1)" "unprognostic (6.08e-3)" "unprognostic (2.77e-2)" "unprognostic (1.76e-1)" "unprognostic (2.14e-1)" "unprognostic (7.07e-2)" "unprognostic (1.32e-1)" "unprognostic (1.97e-1)" "unprognostic (4.96e-2)" "unprognostic (1.02e-1)" "unprognostic (4.86e-1)" OSBPL6 ORP6 ENSG00000079156 "Oxysterol binding protein like 6" Q9BZF3 2 178194481-178402893 "Plasma proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 31.4;tongue: 19.0" "Cell type enhanced" "Detected in many" "Astrocytes: 366.9;Brain excitatory neurons: 271.0;Brain inhibitory neurons: 348.5;Corticotrophs: 324.8;Ependymal cells: 338.1;Myonuclei: 664.7;Pituicytes/FSCs: 526.9;Respiratory ciliated cells: 382.4;Retinal ganglion cells: 359.2;Thymic myoid cells: 1097.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 11.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal medulla cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Skin - Keratinocyte (other), Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032131 Enhanced Supported "Plasma membrane" NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 15 "Plasma membrane" "HPA032131: " "unprognostic (9.47e-2)" "unprognostic (1.50e-1)" "unprognostic (1.50e-2)" "unprognostic (2.29e-1)" "unprognostic (7.17e-2)" "unprognostic (4.48e-2)" "unprognostic (1.82e-1)" "unprognostic (4.14e-2)" "unprognostic (1.65e-2)" "unprognostic (1.27e-2)" "unprognostic (7.34e-2)" "unprognostic (4.40e-3)" "unprognostic (1.14e-1)" "unprognostic (1.30e-1)" "unprognostic (1.36e-1)" "unprognostic (2.21e-3)" "unprognostic (7.60e-2)" "unprognostic (1.17e-1)" "unprognostic (2.08e-2)" "unprognostic (6.47e-2)" "unprognostic (7.45e-3)" "unprognostic (1.40e-1)" "unprognostic (2.00e-2)" OSBPL7 "MGC71150, ORP7" ENSG00000006025 "Oxysterol binding protein like 7" Q9BZF2 17 47807372-47821834 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 42.6;Enterocytes: 39.3;Foveolar cells: 151.6;Goblet cells: 44.9;Mucous neck cells: 29.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036076, HPA053083, HPA073967" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 77: Intestine - Digestion" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 68: Foveolar cells - Mucosal defense" 1 "Nucleoplasm, Cytosol" "Plasma membrane" "HPA036076: , HPA053083: , HPA073967: " "unprognostic (8.47e-3)" "unprognostic (4.60e-1)" "unprognostic (2.75e-1)" "unprognostic (2.05e-1)" "unprognostic (1.64e-1)" "unprognostic (3.03e-1)" "unprognostic (2.95e-2)" "unprognostic (1.45e-3)" "unprognostic (3.30e-2)" "unprognostic (3.30e-3)" "potential prognostic unfavorable (3.52e-4)" "unprognostic (1.34e-1)" "unprognostic (8.73e-3)" "unprognostic (4.46e-3)" "unprognostic (1.47e-2)" "unprognostic (2.33e-1)" "unprognostic (1.98e-1)" "unprognostic (4.44e-1)" "unprognostic (1.26e-1)" "unprognostic (9.92e-2)" "unprognostic (2.52e-1)" "unprognostic (4.31e-2)" "unprognostic (7.99e-2)" "unprognostic (1.88e-1)" "unprognostic (1.96e-3)" "unprognostic (4.99e-1)" "unprognostic (1.27e-2)" "unprognostic (2.42e-1)" "unprognostic (9.23e-2)" "unprognostic (2.09e-1)" "unprognostic (5.87e-2)" OSBPL8 "MST120, MSTP120, ORP8, OSBP10" ENSG00000091039 "Oxysterol binding protein like 8" Q9BZF1 12 76351797-76559809 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 2290.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001309 Uncertain Approved Vesicles,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 61: Non-specific - Transcription" "Cluster 33: Neurons - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 24: Neutrophils - Innate immunity signal integration" 24 "Vesicles, Cytosol" "HPA001309: " "unprognostic (5.69e-3)" "unprognostic (3.15e-1)" "unprognostic (4.26e-2)" "unprognostic (1.24e-2)" "unprognostic (8.43e-2)" "unprognostic (9.38e-3)" "unprognostic (1.43e-1)" "unprognostic (5.28e-2)" "unprognostic (9.42e-3)" "unprognostic (1.90e-3)" "potential prognostic favorable (2.11e-6)" "unprognostic (2.22e-2)" "unprognostic (2.80e-1)" "unprognostic (9.41e-3)" "unprognostic (2.35e-3)" "unprognostic (1.03e-1)" "unprognostic (5.20e-3)" "unprognostic (5.46e-2)" "unprognostic (4.89e-2)" "unprognostic (4.10e-2)" "potential prognostic unfavorable (7.13e-5)" "unprognostic (6.83e-3)" "unprognostic (4.18e-2)" "unprognostic (1.32e-1)" "unprognostic (2.46e-1)" "unprognostic (1.35e-1)" "unprognostic (2.19e-1)" "unprognostic (1.05e-2)" "unprognostic (2.31e-1)" "unprognostic (2.04e-2)" "unprognostic (2.47e-1)" OSBPL9 ENSG00000117859 "Oxysterol binding protein like 9" Q96SU4 1 51577179-51798427 "Plasma proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Myonuclei: 801.7;Neutrophils: 1277.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Endothelial cells, Stomach - Gastric mucous cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027378, HPA027397" Supported Approved Supported "Golgi apparatus,Vesicles" NA NA "Cluster 32: Basophils - Transcription" "Cluster 76: Non-specific - Metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 37: Non-specific - mRNA processing" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 21 "Golgi apparatus" Vesicles "HPA027378: , HPA027397: " "unprognostic (3.90e-1)" "unprognostic (7.41e-2)" "unprognostic (2.89e-1)" "unprognostic (1.37e-2)" "unprognostic (1.38e-2)" "unprognostic (9.07e-3)" "unprognostic (1.44e-2)" "unprognostic (1.15e-1)" "unprognostic (2.79e-2)" "unprognostic (7.36e-3)" "unprognostic (2.13e-2)" "unprognostic (1.15e-1)" "unprognostic (8.93e-2)" "unprognostic (6.65e-3)" "unprognostic (4.02e-2)" "unprognostic (1.80e-1)" "unprognostic (1.83e-1)" "unprognostic (5.79e-2)" "unprognostic (2.80e-1)" "unprognostic (7.66e-2)" "unprognostic (3.89e-1)" "unprognostic (5.57e-3)" "unprognostic (3.38e-2)" "unprognostic (2.73e-1)" "unprognostic (8.46e-2)" "unprognostic (4.56e-2)" "unprognostic (1.71e-2)" "unprognostic (2.15e-2)" "unprognostic (4.64e-1)" "unprognostic (3.58e-2)" "unprognostic (3.27e-3)" OSCAR ENSG00000170909 "Osteoclast associated Ig-like receptor" Q8IYS5 19 54094668-54102692 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 12.6;lung: 27.5;lymphoid tissue: 28.9" "Cell type enhanced" "Detected in some" "cDC: 4.5;Macrophages: 4.6;Microglia: 20.7;monocytes: 11.6;Neutrophil progenitors: 20.0;Neutrophils: 19.8;Oocytes: 4.6" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 23.9;leukocyte: 11.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 35 "classical monocyte: 41.9;eosinophil: 26.4;intermediate monocyte: 28.1;myeloid DC: 19.6;neutrophil: 38.8;non-classical monocyte: 26.7" "Group enriched" "Detected in many" 77 "dendritic cells: 19.6;granulocytes: 38.8;monocytes: 41.9" "Group enriched" "Detected in some" 4 "Leukemia: 8.2;ovarian cancer: 2.5;thyroid cancer: 5.9" "Adipose subcutaneous - Macrophages, Adrenal gland - Macrophages, Kidney - Macrophages, Spleen - Neutrophils_2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA073996 Approved "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" Receptor NA NA 8800000 "Cluster 7: Non-specific - Innate immune response" "Cluster 5: Spleen - Immune response" "Cluster 53: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" "Nucleoplasm, Plasma membrane, Cytosol" "HPA073996: " "unprognostic (4.26e-1)" "unprognostic (3.02e-1)" "unprognostic (1.53e-1)" "unprognostic (1.08e-1)" "unprognostic (3.19e-2)" "unprognostic (1.86e-2)" "unprognostic (9.16e-2)" "unprognostic (2.79e-1)" "unprognostic (1.63e-2)" "unprognostic (2.87e-2)" "unprognostic (1.39e-1)" "unprognostic (8.68e-2)" "unprognostic (6.57e-3)" "unprognostic (5.93e-2)" "unprognostic (5.86e-2)" "unprognostic (1.24e-1)" "unprognostic (1.43e-2)" "unprognostic (1.54e-1)" "unprognostic (2.75e-3)" "unprognostic (1.54e-1)" "unprognostic (1.12e-3)" "unprognostic (1.92e-1)" "unprognostic (2.76e-1)" "unprognostic (4.79e-2)" "unprognostic (3.11e-2)" OSCP1 "C1orf102, NOR1" ENSG00000116885 "Organic solute carrier partner 1" Q8WVF1 1 36415827-36450451 "Predicted intracellular proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 79.1;testis: 72.0" "Cell type enhanced" "Detected in many" "Early spermatids: 436.4;Endometrial ciliated cells: 122.7;Epididymal efferent duct ciliated cells: 195.6;Fallopian tube ciliated cells: 227.5;Late primary spermatocytes: 542.4;Respiratory ciliated cells: 245.8" "Cell type enhanced" "Detected in all" "ependymal cell: 94.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028436 Approved NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" "HPA028436: " "unprognostic (4.59e-2)" "unprognostic (5.28e-2)" "unprognostic (1.32e-3)" "unprognostic (3.38e-3)" "unprognostic (1.75e-2)" "unprognostic (4.85e-2)" "unprognostic (1.71e-2)" "unprognostic (2.35e-1)" "unprognostic (7.07e-2)" "unprognostic (5.70e-3)" "potential prognostic favorable (1.41e-8)" "unprognostic (1.50e-3)" "potential prognostic favorable (2.73e-4)" "unprognostic (5.44e-3)" "unprognostic (2.90e-2)" "unprognostic (3.60e-2)" "unprognostic (3.22e-2)" "unprognostic (1.70e-1)" "unprognostic (3.64e-2)" "unprognostic (8.90e-2)" "unprognostic (9.39e-2)" "unprognostic (7.15e-2)" "unprognostic (1.69e-1)" "unprognostic (3.57e-2)" "unprognostic (5.21e-2)" "unprognostic (2.65e-1)" "unprognostic (2.16e-1)" "unprognostic (2.15e-1)" "unprognostic (2.32e-2)" "potential prognostic unfavorable (4.86e-4)" "unprognostic (6.31e-2)" OSER1 "C20orf111, dJ1183I21.1, HSPC207, Osr1, Perit1" ENSG00000132823 "Oxidative stress responsive serine rich 1" Q9NX31 20 44195939-44210771 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 900.2;Late primary spermatocytes: 609.7;Late spermatids: 3497.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045125 Approved Approved "Nucleoli,Nucleoli rim,Nuclear speckles" NA Yes "Cluster 20: Non-specific - DNA binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 2 "Nucleoli, Nucleoli rim, Nuclear speckles" "HPA045125: " "unprognostic (2.37e-2)" "unprognostic (3.82e-3)" "unprognostic (1.28e-2)" "unprognostic (5.31e-2)" "unprognostic (1.45e-1)" "unprognostic (2.43e-1)" "unprognostic (4.94e-2)" "unprognostic (5.85e-3)" "unprognostic (2.06e-2)" "unprognostic (2.92e-3)" "unprognostic (1.68e-1)" "unprognostic (1.23e-1)" "unprognostic (1.37e-3)" "unprognostic (1.93e-1)" "potential prognostic unfavorable (6.75e-4)" "unprognostic (1.17e-1)" "unprognostic (1.79e-1)" "unprognostic (1.17e-2)" "unprognostic (9.16e-2)" "unprognostic (1.37e-2)" "unprognostic (1.97e-3)" "unprognostic (2.79e-2)" "unprognostic (3.03e-3)" "unprognostic (6.90e-3)" "unprognostic (1.39e-1)" "unprognostic (8.16e-2)" "unprognostic (5.35e-1)" "unprognostic (1.26e-3)" "unprognostic (3.29e-1)" OSGEP "GCPL1, KAE1, OSGEP1, PRSMG1, TCS3" ENSG00000092094 "O-sialoglycoprotein endopeptidase" Q9NPF4 14 20446401-20455089 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "Acyltransferase, Transferase" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Megakaryocytes: 136.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039449, HPA039751" Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 7: Non-specific - Transcription" 53 Nucleoplasm Cytosol "HPA039449: , HPA039751: " "unprognostic (1.98e-2)" "unprognostic (5.90e-2)" "unprognostic (3.93e-2)" "unprognostic (2.17e-1)" "unprognostic (2.97e-2)" "unprognostic (2.60e-2)" "unprognostic (4.64e-1)" "unprognostic (3.57e-2)" "potential prognostic unfavorable (4.07e-5)" "unprognostic (1.91e-1)" "potential prognostic favorable (9.78e-9)" "unprognostic (1.44e-1)" "unprognostic (1.64e-1)" "unprognostic (1.61e-2)" "unprognostic (4.13e-3)" "unprognostic (1.43e-1)" "unprognostic (1.17e-1)" "unprognostic (2.47e-2)" "unprognostic (4.43e-2)" "unprognostic (7.21e-2)" "unprognostic (8.56e-2)" "unprognostic (3.78e-2)" "unprognostic (1.69e-2)" "unprognostic (2.10e-1)" "unprognostic (1.09e-1)" "unprognostic (8.37e-2)" "unprognostic (3.34e-1)" "unprognostic (2.77e-1)" "unprognostic (1.54e-1)" "unprognostic (9.02e-2)" "unprognostic (9.68e-2)" OSGEPL1 "OSGEPL, Qri7" ENSG00000128694 "O-sialoglycoprotein endopeptidase like 1" Q9H4B0 2 189746660-189763227 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 48.2;Cardiomyocytes: 117.2;Epicardial cells: 77.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030693 Uncertain Supported Mitochondria NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" Mitochondria "HPA030693: " "unprognostic (2.72e-1)" "unprognostic (8.08e-2)" "unprognostic (1.94e-1)" "unprognostic (3.42e-1)" "unprognostic (5.20e-2)" "potential prognostic favorable (3.70e-4)" "unprognostic (4.50e-2)" "unprognostic (3.18e-2)" "unprognostic (9.66e-2)" "unprognostic (2.36e-2)" "potential prognostic favorable (1.04e-5)" "unprognostic (3.50e-2)" "unprognostic (5.23e-2)" "unprognostic (3.13e-3)" "unprognostic (2.92e-2)" "unprognostic (1.81e-2)" "unprognostic (3.64e-2)" "unprognostic (3.54e-2)" "unprognostic (8.35e-3)" "unprognostic (1.19e-2)" "unprognostic (2.27e-1)" "unprognostic (2.11e-1)" "unprognostic (9.95e-2)" "unprognostic (1.82e-2)" "unprognostic (1.97e-3)" "unprognostic (1.22e-2)" "unprognostic (2.73e-2)" "unprognostic (1.90e-1)" "unprognostic (1.15e-1)" "unprognostic (5.11e-2)" "unprognostic (3.10e-1)" OSGIN1 "BDGI, OKL38" ENSG00000140961 "Oxidative stress induced growth inhibitor 1" Q9UJX0 16 83931311-83966332 "Predicted intracellular proteins" "Differentiation, Growth regulation" "Developmental protein, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 149.7" "Cell type enriched" "Detected in many" 5 "Late spermatids: 527.6" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 147.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 12.7" "Group enriched" "Detected in many" 8 "granulocytes: 4.2;monocytes: 12.7" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 134.6" "Liver - Hepatocytes, Stomach - Gastric mucous cells, Testis - Late spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA019239 Approved Nucleoplasm,Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 47: Endothelial cells - Vasculature" "Cluster 7: Liver cancer - Metabolism" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 34 "Nucleoplasm, Cytosol" "HPA019239: " "unprognostic (9.91e-2)" "unprognostic (1.70e-1)" "unprognostic (6.60e-2)" "unprognostic (3.32e-2)" "unprognostic (1.10e-2)" "unprognostic (3.30e-3)" "potential prognostic unfavorable (8.32e-4)" "unprognostic (1.31e-1)" "unprognostic (5.03e-3)" "unprognostic (2.37e-1)" "unprognostic (1.09e-1)" "unprognostic (1.62e-1)" "unprognostic (4.53e-2)" "unprognostic (3.52e-2)" "potential prognostic favorable (7.06e-5)" "unprognostic (4.80e-2)" "unprognostic (3.12e-1)" "unprognostic (1.73e-1)" "unprognostic (1.63e-1)" "unprognostic (1.71e-1)" "unprognostic (8.29e-2)" "unprognostic (2.32e-3)" "unprognostic (9.65e-2)" "unprognostic (4.33e-1)" "unprognostic (2.42e-1)" "unprognostic (5.65e-2)" "unprognostic (4.34e-1)" "unprognostic (1.78e-2)" "unprognostic (2.06e-2)" "unprognostic (1.49e-2)" "unprognostic (5.45e-2)" OSGIN2 "C8orf1, hT41" ENSG00000164823 "Oxidative stress induced growth inhibitor family member 2" Q9Y236 8 89901849-89927888 "Predicted intracellular proteins" Meiosis "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 171.7;Early spermatids: 310.3;Late primary spermatocytes: 154.9;Late spermatids: 336.4;Pituicytes/FSCs: 125.0" "Cell type enhanced" "Detected in all" "astrocyte: 101.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 21.8;eosinophil: 7.0;neutrophil: 12.1" "Lineage enriched" "Detected in all" 6 "granulocytes: 21.8" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028515, HPA050595" Approved Approved Nucleoli NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 61: Non-specific - Transcription" "Cluster 39: Astrocytes - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" Nucleoli "HPA028515: , HPA050595: " "unprognostic (1.53e-2)" "unprognostic (2.26e-3)" "unprognostic (1.69e-1)" "unprognostic (7.19e-2)" "unprognostic (5.22e-2)" "unprognostic (3.49e-2)" "unprognostic (4.12e-2)" "potential prognostic favorable (4.10e-4)" "unprognostic (3.62e-2)" "unprognostic (5.02e-2)" "potential prognostic favorable (5.60e-5)" "unprognostic (1.81e-1)" "unprognostic (1.51e-3)" "potential prognostic unfavorable (1.80e-5)" "unprognostic (1.24e-2)" "potential prognostic unfavorable (4.10e-4)" "unprognostic (5.39e-2)" "unprognostic (5.46e-2)" "unprognostic (2.36e-1)" "unprognostic (2.05e-3)" "unprognostic (5.24e-3)" "potential prognostic unfavorable (3.76e-4)" "unprognostic (1.74e-2)" "unprognostic (2.08e-1)" "unprognostic (2.27e-1)" "unprognostic (6.14e-2)" "unprognostic (3.70e-1)" "unprognostic (1.91e-1)" "unprognostic (4.15e-1)" "unprognostic (8.02e-2)" "unprognostic (1.38e-2)" OSM MGC20461 ENSG00000099985 "Oncostatin M" P13725 22 30262829-30266851 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth regulation" "Cytokine, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "bone marrow: 111.7" "Cell type enriched" "Detected in some" 6 "Neutrophils: 519.0" "Group enriched" "Detected in some" 24 "central nervous system macrophage: 1.9;leukocyte: 3.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 8 "basophil: 65.5;neutrophil: 35.0" "Lineage enriched" "Detected in many" 10 "granulocytes: 65.5" "Cancer enhanced" "Detected in some" "Leukemia: 11.1;lymphoma: 6.2" "Colon - Neutrophils" "Not detected" "Not detected" "Region enriched" "Detected in single" 6 "spinal cord: 3.3" "Secreted to blood" Cytokine NA NA 39700 "Cluster 35: Neutrophils - Protein binding" "Cluster 15: Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 5 "unprognostic (2.05e-1)" "unprognostic (1.50e-1)" "unprognostic (3.31e-1)" "unprognostic (1.26e-2)" "unprognostic (4.54e-2)" "unprognostic (5.19e-2)" "unprognostic (1.56e-2)" "unprognostic (1.04e-1)" "unprognostic (9.11e-2)" "unprognostic (1.27e-1)" "potential prognostic unfavorable (5.74e-5)" "unprognostic (1.05e-1)" "unprognostic (1.25e-1)" "unprognostic (1.39e-1)" "unprognostic (3.92e-1)" "unprognostic (1.53e-2)" "unprognostic (5.85e-2)" "unprognostic (1.49e-1)" "unprognostic (7.62e-3)" "unprognostic (3.13e-1)" "unprognostic (9.08e-3)" "unprognostic (1.98e-1)" "unprognostic (8.26e-2)" "unprognostic (1.46e-2)" "unprognostic (3.13e-1)" "unprognostic (6.54e-2)" "unprognostic (3.23e-2)" "unprognostic (6.58e-2)" "unprognostic (6.60e-2)" "unprognostic (2.48e-1)" OSMR "OSMRB, OSMRbeta" ENSG00000145623 "Oncostatin M receptor" Q99650 5 38845858-38945596 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 313.9;Alveolar cells type 2: 333.0;Breast lactating cells: 344.5;Endometrial secretory cells: 280.3;Epicardial cells: 450.3;Medullary thymic epithelial cells: 285.6;Mesothelial cells: 300.2;Pancreatic acinar cells: 295.7;Pericytes: 348.4;Salivary acinar cells: 280.3;Salivary basal cells: 481.6;Salivary myoepithelial cells: 342.7;Smooth muscle cells: 416.3;Transitional alveolar cells: 367.0;Vascular endothelial cells: 301.9" "Cell type enriched" "Detected in all" 4 "endothelial cell: 323.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA017278 Approved Approved Nucleoli "Intracellular and membrane" Receptor NA NA 8900000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 103: Non-specific - Basic cellular processes" 35 Nucleoli "HPA017278: " "unprognostic (6.62e-2)" "unprognostic (1.75e-2)" "unprognostic (2.90e-3)" "unprognostic (1.45e-3)" "unprognostic (9.06e-2)" "unprognostic (9.11e-2)" "potential prognostic unfavorable (2.04e-4)" "unprognostic (1.42e-3)" "unprognostic (1.23e-1)" "unprognostic (3.82e-1)" "unprognostic (2.92e-3)" "unprognostic (3.20e-1)" "unprognostic (1.64e-2)" "unprognostic (7.78e-3)" "unprognostic (9.60e-2)" "unprognostic (2.02e-2)" "potential prognostic unfavorable (2.92e-4)" "unprognostic (7.61e-2)" "unprognostic (3.70e-2)" "unprognostic (4.51e-3)" "potential prognostic unfavorable (3.33e-4)" "potential prognostic unfavorable (9.13e-4)" "unprognostic (1.13e-3)" "unprognostic (2.99e-1)" "unprognostic (2.13e-1)" "unprognostic (3.12e-2)" "unprognostic (3.78e-3)" "unprognostic (2.48e-2)" "unprognostic (1.17e-1)" "unprognostic (3.09e-1)" "unprognostic (4.93e-2)" OSR1 ODD ENSG00000143867 "Odd-skipped related transcription factor 1" Q8TAX0 2 19351485-19358623 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 100.1;urinary bladder: 69.7" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 15.5;Epicardial cells: 20.5;Fibroblasts: 30.4;Leydig cells: 117.7;Mesothelial cells: 40.4;Peritubular myoid cells: 44.9;Prostatic club cells: 18.2;Salivary myoepithelial cells: 34.6;Smooth muscle cells: 20.2;Urothelial cells: 13.0" "Cell type enhanced" "Detected in some" "fibroblast: 17.3;hippocampal CA4: 8.3" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 22.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 9.9;Gastric cancer: 9.0;Sarcoma: 9.2" "Adipose visceral - Mesothelial cells, Lung - Fibroblasts_2, Spleen - Smooth muscle cells, Stomach - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA015525 Uncertain NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 2 "HPA015525: " "unprognostic (3.46e-1)" "unprognostic (1.44e-3)" "unprognostic (3.20e-1)" "unprognostic (1.99e-1)" "unprognostic (9.15e-2)" "unprognostic (1.34e-1)" "unprognostic (5.61e-3)" "unprognostic (4.79e-2)" "unprognostic (1.99e-2)" "unprognostic (1.60e-2)" "unprognostic (1.11e-1)" "unprognostic (3.80e-2)" "unprognostic (3.69e-2)" "unprognostic (3.11e-1)" "unprognostic (4.11e-2)" "unprognostic (2.81e-1)" "unprognostic (4.17e-2)" "unprognostic (9.10e-2)" "unprognostic (6.15e-2)" "unprognostic (2.35e-1)" "unprognostic (5.75e-2)" "potential prognostic unfavorable (6.44e-4)" "unprognostic (1.22e-1)" "unprognostic (1.51e-1)" "unprognostic (2.51e-1)" "unprognostic (3.38e-2)" OSR2 FLJ90037 ENSG00000164920 "Odd-skipped related transciption factor 2" Q8N2R0 8 98944403-98952104 "Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 149.8;endometrium 1: 161.9;fallopian tube: 151.8" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 1197.5;Endometrial stromal cells: 205.9;Extravillous trophoblasts: 228.2;Fibroblasts: 126.3;Leydig cells: 725.1;Ovarian stromal cells: 248.0;Peritubular myoid cells: 813.0;Smooth muscle cells: 114.8" "Cell type enhanced" "Detected in single" "fibroblast: 2.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblasts_2, Minor Salivary Gland - Fibroblasts, Prostate - Fibroblasts, Skin - Fibroblasts_2, Spleen - Smooth muscle cells" "Not detected" "Not detected" "Region enriched" "Detected in single" 6 "spinal cord: 1.1" "HPA052425, HPA063486" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 94: Gonadal somatic cells - Mixed function" 1 "Plasma membrane" Nucleoplasm "HPA052425: , HPA063486: " "unprognostic (2.32e-1)" "unprognostic (2.18e-1)" "unprognostic (2.29e-1)" "unprognostic (4.18e-2)" "unprognostic (1.15e-1)" "unprognostic (1.03e-2)" "unprognostic (3.17e-1)" "unprognostic (9.14e-2)" "potential prognostic favorable (1.95e-4)" "unprognostic (4.10e-2)" "unprognostic (5.31e-3)" "unprognostic (7.93e-2)" "unprognostic (2.39e-3)" "unprognostic (1.22e-2)" "unprognostic (1.42e-2)" "unprognostic (1.18e-2)" "unprognostic (7.72e-2)" "unprognostic (1.13e-3)" "unprognostic (2.57e-1)" "potential prognostic unfavorable (4.91e-4)" "unprognostic (1.05e-1)" "unprognostic (3.72e-2)" "unprognostic (7.61e-2)" "unprognostic (8.24e-2)" "unprognostic (6.30e-2)" "unprognostic (1.99e-1)" "unprognostic (9.53e-2)" "unprognostic (2.23e-2)" "unprognostic (1.46e-1)" "potential prognostic unfavorable (6.35e-4)" "unprognostic (2.75e-2)" OST4 ENSG00000228474 "Oligosaccharyltransferase complex subunit 4, non-catalytic" P0C6T2 2 27070472-27071654 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1568.8;Megakaryocytes: 3195.9;Platelets: 5797.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 47: Platelets - Hemostasis" 99 "unprognostic (2.86e-1)" "unprognostic (7.18e-2)" "unprognostic (6.03e-2)" "unprognostic (1.06e-1)" "unprognostic (1.53e-1)" "unprognostic (2.17e-2)" "unprognostic (1.86e-1)" "unprognostic (9.51e-2)" "potential prognostic unfavorable (2.28e-5)" "unprognostic (1.98e-2)" "unprognostic (9.37e-3)" "potential prognostic unfavorable (6.04e-6)" "unprognostic (4.53e-2)" "validated prognostic unfavorable (2.25e-5)" "validated prognostic unfavorable (3.10e-4)" "unprognostic (5.04e-2)" "unprognostic (2.50e-2)" "unprognostic (2.16e-2)" "unprognostic (2.11e-1)" "unprognostic (1.46e-2)" "unprognostic (9.03e-3)" "unprognostic (4.00e-2)" "unprognostic (2.56e-2)" "unprognostic (3.63e-1)" "unprognostic (8.85e-2)" "unprognostic (5.92e-3)" "unprognostic (6.48e-2)" "unprognostic (3.68e-2)" "unprognostic (1.22e-1)" "unprognostic (2.95e-1)" "unprognostic (1.63e-2)" OSTC DC2 ENSG00000198856 "Oligosaccharyltransferase complex non-catalytic subunit" Q9NRP0 4 108650585-108667820 "Essential proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Decidual stromal cells: 598.7;Epididymal principal cells: 461.6;Extravillous trophoblasts: 833.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 8: Non-specific - Secretory pathway" 16 "unprognostic (2.62e-3)" "unprognostic (2.96e-3)" "unprognostic (9.47e-2)" "unprognostic (7.22e-2)" "unprognostic (2.24e-1)" "unprognostic (5.57e-2)" "unprognostic (5.56e-2)" "unprognostic (2.45e-3)" "potential prognostic unfavorable (4.51e-4)" "unprognostic (3.24e-2)" "unprognostic (1.74e-3)" "unprognostic (9.82e-2)" "potential prognostic unfavorable (1.19e-4)" "unprognostic (4.90e-3)" "potential prognostic unfavorable (2.08e-4)" "potential prognostic unfavorable (1.05e-4)" "unprognostic (1.18e-2)" "unprognostic (1.84e-1)" "unprognostic (3.87e-2)" "unprognostic (1.68e-1)" "unprognostic (7.61e-3)" "unprognostic (1.72e-2)" "unprognostic (3.30e-2)" "unprognostic (1.17e-2)" "unprognostic (1.74e-2)" "unprognostic (9.82e-2)" "unprognostic (4.21e-2)" "unprognostic (1.48e-1)" "unprognostic (3.39e-1)" "unprognostic (4.07e-3)" "unprognostic (1.17e-2)" OSTF1 "bA235O14.1, OSF, SH3P2" ENSG00000134996 "Osteoclast stimulating factor 1" Q92882 9 75088514-75147265 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1097.7;Extravillous trophoblasts: 375.0;Hofbauer cells: 394.0;Neutrophil progenitors: 358.2;Neutrophils: 713.7" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 187.9;leukocyte: 166.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020514 Approved Supported Cytosol NA NA 430000 "Cluster 21: Neutrophils - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" 27 Cytosol "HPA020514: " "unprognostic (1.83e-1)" "unprognostic (3.34e-2)" "unprognostic (1.82e-2)" "unprognostic (6.75e-2)" "unprognostic (1.10e-1)" "unprognostic (3.93e-3)" "unprognostic (7.65e-2)" "unprognostic (1.65e-1)" "unprognostic (6.13e-2)" "unprognostic (7.41e-2)" "potential prognostic favorable (1.07e-4)" "unprognostic (1.40e-2)" "unprognostic (5.28e-3)" "unprognostic (1.79e-2)" "unprognostic (1.26e-1)" "unprognostic (1.49e-2)" "unprognostic (6.70e-3)" "unprognostic (3.13e-1)" "unprognostic (1.43e-1)" "unprognostic (4.96e-2)" "unprognostic (3.13e-1)" "unprognostic (4.55e-3)" "unprognostic (2.64e-1)" "unprognostic (2.07e-1)" "unprognostic (1.50e-1)" "unprognostic (1.94e-1)" "unprognostic (4.34e-1)" "unprognostic (1.18e-1)" "unprognostic (5.77e-3)" "unprognostic (3.42e-1)" "unprognostic (2.25e-2)" OSTM1 "GL, HSPC019" ENSG00000081087 "Osteoclastogenesis associated transmembrane protein 1" Q86WC4 6 108029245-108165854 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Osteopetrosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Melanocytes: 443.4;Neutrophils: 191.5;Retinal pigment epithelial cells: 247.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010851 Uncertain Approved Nucleoplasm,Vesicles,Cytosol No No 77000 "Cluster 28: Neutrophils - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 21: Non-specific - Metabolism" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 61: Schwann cells & Melanocytes - Mixed function" 6 Cytosol "Nucleoplasm, Vesicles" "HPA010851: " "unprognostic (2.99e-1)" "unprognostic (3.97e-3)" "potential prognostic unfavorable (4.14e-5)" "unprognostic (6.06e-3)" "unprognostic (2.06e-1)" "unprognostic (1.92e-1)" "unprognostic (4.14e-1)" "unprognostic (5.26e-3)" "unprognostic (5.01e-3)" "unprognostic (9.84e-3)" "potential prognostic favorable (2.20e-6)" "unprognostic (3.90e-2)" "unprognostic (1.78e-2)" "unprognostic (1.16e-2)" "unprognostic (2.56e-2)" "unprognostic (3.23e-1)" "unprognostic (1.33e-1)" "unprognostic (9.39e-3)" "unprognostic (7.84e-2)" "unprognostic (6.16e-2)" "potential prognostic unfavorable (4.46e-5)" "unprognostic (4.78e-2)" "unprognostic (2.39e-1)" "unprognostic (1.38e-1)" "unprognostic (3.04e-2)" "unprognostic (5.89e-3)" "unprognostic (9.64e-2)" "unprognostic (3.97e-3)" "unprognostic (3.05e-1)" "unprognostic (2.95e-1)" "unprognostic (8.85e-2)" OSTN ENSG00000188729 Osteocrin P61366 3 191199241-191265615 "Predicted secreted proteins" Differentiation "Developmental protein, Hormone" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.2;cervix: 1.0" "Cell type enhanced" "Detected in some" "Adipocytes: 7.4;B-cells: 10.9;Bergmann glia: 19.0;Choroid plexus epithelial cells: 5.4;Early spermatids: 7.5;Ependymal cells: 6.5;Late primary spermatocytes: 8.9;Parietal cells: 5.3;pDCs: 5.7;Thymic myoid cells: 10.9" "Cell type enhanced" "Detected in many" "Bergmann glia: 24.9;MGE interneuron: 26.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 29 "Rhabdoid: 37.1" "Region enriched" "Detected in single" 4 "cerebellum: 1.0" "Low region specificity" "Detected in some" "CAB024997, CAB025649, HPA030878" Uncertain "Secreted in other tissues" Hormone NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 87: B-cells - Adaptive immunity: Humoral response" "CAB024997: , CAB025649: , HPA030878: " "unprognostic (1.03e-2)" OTC "OTC1, OTCase, OTCD" ENSG00000036473 "Ornithine transcarbamylase" P00480 X 38352586-38421446 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Arginine biosynthesis, Urea cycle" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 122 "intestine: 105.7;liver: 353.1" "Cell type enhanced" "Detected in some" "Enteric stem cells: 23.7;Enteric transient amplifying cells: 37.6;Enterocytes: 82.9;Hepatocytes: 136.0;Lymphatic endothelial cells: 28.5;Paneth cells: 46.4" "Low cell type specificity" "Detected in single" "Cancer enriched" "Detected in some" 18 "Liver Hepatocellular Carcinoma (TCGA): 75.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "colorectal cancer: 1.0" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA000243, HPA000570" Enhanced Supported Mitochondria NA NA 4400000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 1: Enterocytes - Absorption and Digestion" 2 Mitochondria "HPA000243: , HPA000570: " "unprognostic (1.48e-1)" "unprognostic (1.72e-1)" "unprognostic (6.77e-3)" "unprognostic (3.12e-2)" "unprognostic (3.44e-2)" "unprognostic (1.34e-2)" "unprognostic (1.98e-2)" "potential prognostic unfavorable (8.34e-4)" "unprognostic (1.65e-2)" OTOA "CT108, DFNB22" ENSG00000155719 Otoancorin Q7RTW8 16 21663968-21761935 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Hearing "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "lymphoid tissue: 1.9;testis: 3.8" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 10.6;Hofbauer cells: 51.6;Kupffer cells: 38.9;Late primary spermatocytes: 6.7;Late spermatids: 12.5;Macrophages: 9.6" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 7.6" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.3" "Lineage enriched" "Detected in single" 10 "dendritic cells: 1.3" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Lung - Macrophages, Minor Salivary Gland - Macrophages, Spleen - Macrophages, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA041405 Enhanced "Secreted in other tissues" Other NA NA 33000 "Cluster 39: Testis - Nuclear processes" "Cluster 5: Rhabdoid - Unknown function" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" "HPA041405: " "unprognostic (3.25e-2)" "potential prognostic favorable (5.48e-4)" OTOF "DFNB6, DFNB9, FER1L2" ENSG00000115155 Otoferlin Q9HC10 2 26457203-26558756 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Hearing "Deafness, Disease variant, Neuropathy, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "bone marrow: 6.1;brain: 20.8" "Cell type enriched" "Detected in some" 4 "Brain inhibitory neurons: 46.9" "Group enriched" "Detected in many" 5 "eccentric medium spiny neuron: 169.3;medium spiny neuron: 116.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 2.3;lymphoma: 1.9" "Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA012410 Uncertain NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 35: Neurons - Synaptic function & neurogenesis" "HPA012410: " "unprognostic (4.51e-2)" "unprognostic (2.29e-1)" "unprognostic (4.31e-1)" OTOG "FLJ46346, mlemp, OTGN" ENSG00000188162 Otogelin Q6ZRI0 11 17547259-17647150 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "pituitary gland: 1.2" "Group enriched" "Detected in some" 4 "Early spermatids: 48.7;Late spermatids: 40.2" "Cell type enhanced" "Detected in some" "astrocyte: 2.3;hippocampal CA4: 3.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" "No annotated function" NA NA "Cluster 47: Testis - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" OTOGL "C12orf64, FLJ90579" ENSG00000165899 "Otogelin like" Q3ZCN5 12 80099537-80380880 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "heart muscle: 4.1;intestine: 1.5;kidney: 4.8" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 30.9;Epididymal efferent duct absorptive cells: 51.5;Medullary thymic epithelial cells: 196.8;Myonuclei: 82.7;Oligodendrocyte progenitor cells: 60.3;Pancreatic islet cells: 28.2;Pituitary stem cells: 37.9;Proximal tubule cells: 65.3;Schwann cells: 70.5" "Cell type enhanced" "Detected in many" "deep-layer intratelencephalic: 104.4;miscellaneous: 146.5;upper-layer intratelencephalic: 129.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Myeloma: 1.5" "Colon - Enteric glia cells, Kidney - Proximal tubular cells, Minor Salivary Gland - Minor salivary gland ductal cells, Pancreas - Alpha cells, Pancreas - Beta cells, Pituitary gland - Lactotropes, Prostate - Smooth muscle cells" "Not detected" "Not detected" "Region enriched" "Detected in single" 6 "basal ganglia: 5.5" "HPA040364, HPA053392" Uncertain Approved Cytosol "Secreted in other tissues" "No annotated function" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 53: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" 1 Cytosol "HPA040364: , HPA053392: " "potential prognostic favorable (8.09e-4)" OTOL1 "C1QTNF15, C1QTNF16" ENSG00000182447 "Otolin 1" A6NHN0 3 161496808-161503942 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 5 "deep-layer corticothalamic and 6b: 1.9" "Not detected" "Not detected" "Region enriched" "Detected in single" 6 "cerebral cortex: 2.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 21 "cervical cancer: 8.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA041030 Uncertain "Secreted in other tissues" "No annotated function" NA NA "Cluster 51: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" 1 "HPA041030: " OTOP1 ENSG00000163982 "Otopetrin 1" Q7RTM1 4 4188726-4226929 "Predicted membrane proteins, Transporters" "Biomineralization, Hydrogen ion transport, Ion transport, Transport" "Ion channel" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 2.1;Early spermatids: 2.1;Medullary thymic epithelial cells: 2.4;Neutrophil progenitors: 1.9;Neutrophils: 4.0;pDCs: 1.8;Thymic myoid cells: 2.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA035599 Uncertain NA NA "Cluster 32: Non-specific - Cell proliferation" "Cluster 29: Neutrophils - Innate immune cellular maintenance" "HPA035599: " OTOP2 ENSG00000183034 "Otopetrin 2" Q7RTS6 17 74922950-74933912 "Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "intestine: 18.8;testis: 4.7" "Group enriched" "Detected in some" 4 "Colonocytes: 122.6;Late spermatids: 35.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Gallbladder cancer: 2.0" "Colon - Colon enterocytes, Skin - Hair cortex cells, Skin - Inner root sheath cells, Testis - Late spermatids" "Region enriched" "Detected in some" 12 "olfactory bulb: 12.7" "Low region specificity" "Detected in all" "HPA024524, HPA053090" Uncertain Approved "Plasma membrane" NA NA "Cluster 17: Intestine - Digestion" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 4 "Plasma membrane" "HPA024524: , HPA053090: " OTOP3 ENSG00000182938 "Otopetrin 3" 17 74935898-74949992 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "intestine: 74.9" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 5.7;Colonocytes: 5.6;Enterocytes: 20.3;Esophageal apical cells: 61.7;Esophageal basal cells: 14.7;Esophageal suprabasal cells: 68.4;Suprabasal keratinocytes: 18.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Head and Neck Squamous Cell Carcinoma (TCGA): 4.5;Lung Squamous Cell Carcinoma (TCGA): 2.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "cervical cancer: 27.4;thyroid cancer: 9.3" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" "potential prognostic favorable (6.69e-4)" "unprognostic (3.57e-2)" OTOR "FDP, MIAL, MIAL1" ENSG00000125879 Otoraplin Q9NRC9 20 16748358-16770062 "Predicted secreted proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 6 "Schwann cells: 5.4" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Uterine Corpus Endometrial Carcinoma (TCGA): 1.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "breast cancer: 1.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA024335 Uncertain "Secreted in other tissues" "No annotated function" NA NA "Cluster 27: Breast cancer - Unknown function" "Cluster 107: Ciliated cells - Cilia assembly & function" 1 "HPA024335: " "unprognostic (4.08e-2)" OTOS OTOSP ENSG00000178602 Otospiralin Q8NHW6 2 240139026-240144562 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "pituitary gland: 105.7;thyroid gland: 41.0" "Cell type enriched" "Detected in some" 6 "Epididymal efferent duct absorptive cells: 367.3" "Cell type enhanced" "Detected in some" "mammillary body: 7.6;thalamic excitatory: 2.5" "Cancer enriched" "Detected in some" 4 "Thyroid Carcinoma (TCGA): 63.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 59 "thyroid cancer: 12.8" "Pituitary gland - Somatotropes" "Region enriched" "Detected in single" 4 "hippocampal formation: 1.6" "Low region specificity" "Detected in many" "Secreted in other tissues" "No annotated function" NA NA "Cluster 20: Pituitary gland - Hormone signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 3 "unprognostic (1.31e-1)" "unprognostic (1.16e-2)" "unprognostic (1.73e-1)" "unprognostic (3.85e-1)" "unprognostic (2.29e-3)" "unprognostic (2.56e-2)" OTP ENSG00000171540 "Orthopedia homeobox" Q5XKR4 5 77628712-77638713 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 70 "brain: 17.3" "Group enriched" "Detected in some" 12 "Early primary spermatocytes: 6.4;Other brain neurons: 19.6" "Group enriched" "Detected in some" 9 "amygdala excitatory: 5.0;splatter: 3.9" "Cancer enhanced" "Detected in single" "Glioblastoma Multiforme (TCGA): 3.0" "Region enhanced" "Detected in many" "hypothalamus: 61.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 21 "lymphoma: 12.7;Rhabdoid: 6.1" "Region enriched" "Detected in many" 7 "hypothalamus: 20.0" "Group enriched" "Detected in some" 4 "basal ganglia: 8.4;hypothalamus: 22.7" HPA059342 Enhanced Supported Approved "Nucleoplasm,Nucleoli fibrillar center,Nuclear bodies" NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 59: Leukemia - T-cell receptor" "Cluster 109: Neurons - Neuronal signaling" 5 Nucleoplasm "Nucleoli fibrillar center, Nuclear bodies" "HPA059342: " "unprognostic (2.63e-2)" "potential prognostic unfavorable (1.55e-5)" OTUB1 "FLJ20113, FLJ40710" ENSG00000167770 "OTU deubiquitinase, ubiquitin aldehyde binding 1" Q96FW1 11 63985853-64001811 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, DNA damage, DNA repair, Immunity, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 185.0;Syncytiotrophoblasts: 233.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039176, CAB072836, CAB080075" Approved Supported Approved "Cytosol,Cytoplasmic bodies" NA NA 1200000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 24: Non-specific - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 114 Cytosol "Cytoplasmic bodies" "CAB072836: , CAB080075: , HPA039176: " "unprognostic (1.77e-2)" "unprognostic (3.59e-2)" "unprognostic (2.74e-2)" "unprognostic (4.35e-1)" "unprognostic (2.58e-2)" "unprognostic (6.13e-2)" "unprognostic (5.44e-1)" "unprognostic (1.16e-1)" "unprognostic (1.26e-3)" "unprognostic (4.52e-2)" "potential prognostic favorable (3.30e-4)" "unprognostic (2.50e-1)" "unprognostic (2.18e-2)" "unprognostic (1.68e-3)" "unprognostic (1.21e-3)" "validated prognostic unfavorable (7.99e-4)" "validated prognostic unfavorable (3.21e-5)" "unprognostic (1.51e-1)" "unprognostic (2.89e-1)" "unprognostic (3.75e-2)" "unprognostic (3.26e-1)" "unprognostic (2.06e-2)" "unprognostic (1.97e-3)" "unprognostic (1.18e-1)" "unprognostic (4.71e-3)" "unprognostic (1.42e-1)" "unprognostic (1.28e-1)" "unprognostic (2.52e-1)" "unprognostic (2.45e-1)" "unprognostic (1.57e-2)" "unprognostic (2.33e-1)" OTUB2 "C14orf137, FLJ21916, MGC3102" ENSG00000089723 "OTU deubiquitinase, ubiquitin aldehyde binding 2" Q96DC9 14 94026340-94048930 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "esophagus: 3.7;skin 1: 7.2;testis: 13.2" "Group enriched" "Detected in some" 34 "Early spermatids: 702.4;Late spermatids: 1712.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002329, HPA075090" Enhanced NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 47: Testis - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 32 "HPA002329: , HPA075090: " "unprognostic (1.36e-1)" "unprognostic (1.12e-1)" "unprognostic (1.44e-1)" "potential prognostic unfavorable (8.68e-5)" "unprognostic (5.27e-2)" "unprognostic (5.44e-2)" "unprognostic (4.46e-3)" "unprognostic (3.95e-1)" "unprognostic (7.47e-2)" "unprognostic (3.18e-1)" "unprognostic (1.12e-1)" "unprognostic (2.76e-3)" "unprognostic (6.02e-2)" "unprognostic (2.46e-1)" "unprognostic (3.79e-2)" "unprognostic (4.67e-3)" "unprognostic (1.51e-2)" "unprognostic (2.47e-1)" "unprognostic (1.16e-1)" "unprognostic (2.31e-1)" "unprognostic (7.83e-2)" "unprognostic (1.16e-1)" "unprognostic (1.18e-1)" "unprognostic (1.81e-1)" "unprognostic (7.83e-2)" OTUD1 "DUBA7, OTDC1" ENSG00000165312 "OTU deubiquitinase 1" Q5VV17 10 23439075-23442377 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 57.0" "Cell type enhanced" "Detected in some" "Astrocytes: 4.2;Bergmann glia: 4.9;Brain excitatory neurons: 6.4;Brain inhibitory neurons: 5.9;Distal convoluted tubule cells: 6.5;Ependymal cells: 4.4;Loop of henle epithelial cells: 6.4;Microglia: 33.7;Oligodendrocyte progenitor cells: 5.8;Oligodendrocytes: 5.8;Other brain neurons: 6.4;Papillary tip epithelial cells: 5.3;Podocytes: 9.5;Proximal tubule cells: 6.4;Renal collecting duct intercalated cells: 6.6;Renal collecting duct principal cells: 4.4;Renal connecting tubule cells: 8.4" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 34.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "cervical cancer: 32.3" "Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038504 Approved Approved Cytosol NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 22 Cytosol "HPA038504: " "unprognostic (3.05e-1)" "unprognostic (4.81e-2)" "unprognostic (8.40e-2)" "unprognostic (1.27e-1)" "unprognostic (3.73e-2)" "unprognostic (5.21e-2)" "unprognostic (1.18e-1)" "unprognostic (2.09e-3)" "unprognostic (3.29e-2)" "unprognostic (3.58e-1)" "validated prognostic favorable (5.78e-8)" "validated prognostic favorable (1.89e-4)" "unprognostic (7.08e-2)" "unprognostic (4.75e-3)" "unprognostic (4.86e-3)" "unprognostic (9.40e-2)" "unprognostic (1.73e-1)" "unprognostic (3.55e-1)" "unprognostic (8.47e-2)" "unprognostic (3.45e-1)" "unprognostic (4.38e-3)" "unprognostic (2.77e-2)" "potential prognostic unfavorable (2.08e-4)" "unprognostic (1.52e-1)" "unprognostic (1.33e-2)" "unprognostic (2.23e-1)" "unprognostic (9.20e-2)" "unprognostic (1.83e-1)" "unprognostic (5.79e-2)" "unprognostic (2.31e-1)" "unprognostic (2.99e-1)" OTUD3 "DUBA4, KIAA0459" ENSG00000169914 "OTU deubiquitinase 3" Q5T2D3 1 19882395-19912945 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028543, HPA028544" Approved Approved "Nucleoplasm,Intermediate filaments,Cytosol" NA NA "Cluster 67: Testis - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" 20 Cytosol "Nucleoplasm, Intermediate filaments" "HPA028543: , HPA028544: " "unprognostic (3.43e-2)" "unprognostic (1.79e-3)" "unprognostic (1.76e-1)" "unprognostic (1.48e-2)" "unprognostic (4.07e-1)" "unprognostic (4.68e-2)" "unprognostic (3.23e-1)" "unprognostic (4.02e-2)" "potential prognostic favorable (7.61e-4)" "unprognostic (1.56e-2)" "unprognostic (2.69e-3)" "potential prognostic favorable (5.19e-4)" "unprognostic (1.02e-2)" "unprognostic (1.02e-2)" "unprognostic (7.41e-2)" "unprognostic (1.30e-1)" "unprognostic (1.20e-1)" "potential prognostic favorable (2.05e-4)" "unprognostic (1.03e-1)" "unprognostic (1.59e-1)" "unprognostic (2.94e-2)" "unprognostic (5.49e-2)" "unprognostic (3.94e-2)" "unprognostic (2.98e-2)" "unprognostic (4.61e-3)" "unprognostic (1.48e-1)" "unprognostic (1.42e-1)" "unprognostic (2.47e-1)" "unprognostic (2.70e-2)" "unprognostic (1.48e-1)" OTUD4 "DUBA6, HSHIN1, KIAA1046" ENSG00000164164 "OTU deubiquitinase 4" Q01804 4 145110838-145180589 "Enzymes, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 241.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036623 Uncertain Supported Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 16: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 22 Cytosol "HPA036623: " "unprognostic (2.05e-1)" "unprognostic (3.44e-1)" "unprognostic (1.01e-1)" "unprognostic (3.76e-2)" "unprognostic (1.13e-1)" "unprognostic (1.78e-1)" "unprognostic (1.25e-1)" "unprognostic (1.16e-2)" "unprognostic (2.49e-2)" "unprognostic (8.89e-2)" "validated prognostic favorable (8.82e-4)" "validated prognostic favorable (1.45e-4)" "unprognostic (2.91e-1)" "unprognostic (4.67e-3)" "unprognostic (2.23e-2)" "unprognostic (1.52e-1)" "unprognostic (1.74e-2)" "unprognostic (7.04e-2)" "unprognostic (3.15e-1)" "unprognostic (1.28e-2)" "unprognostic (1.40e-1)" "potential prognostic unfavorable (7.96e-4)" "unprognostic (2.01e-3)" "unprognostic (2.15e-2)" "unprognostic (1.13e-2)" "unprognostic (3.86e-2)" "unprognostic (6.75e-2)" "unprognostic (2.21e-1)" "unprognostic (3.03e-1)" "unprognostic (2.63e-2)" "unprognostic (1.15e-1)" OTUD5 "DKFZp761A052, DUBA" ENSG00000068308 "OTU deubiquitinase 5" Q96G74 X 48922024-48958386 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 214.7;Platelets: 151.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017375 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 64: Non-specific - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 20: Myeloma - Immune response" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 14 Cytosol "Nucleoplasm, Nucleoli fibrillar center" "HPA017375: " "unprognostic (3.54e-2)" "unprognostic (2.37e-1)" "unprognostic (2.29e-1)" "unprognostic (2.82e-2)" "unprognostic (2.30e-1)" "unprognostic (7.67e-2)" "unprognostic (2.71e-1)" "potential prognostic favorable (5.12e-4)" "unprognostic (1.50e-1)" "unprognostic (1.70e-2)" "unprognostic (3.28e-3)" "unprognostic (1.20e-1)" "unprognostic (3.34e-1)" "unprognostic (2.47e-2)" "unprognostic (1.59e-1)" "unprognostic (4.04e-2)" "unprognostic (1.57e-1)" "unprognostic (3.68e-3)" "unprognostic (2.34e-2)" "unprognostic (6.14e-2)" "unprognostic (1.08e-1)" "unprognostic (8.33e-3)" "unprognostic (4.17e-2)" "unprognostic (2.37e-1)" "unprognostic (4.04e-2)" "unprognostic (4.48e-3)" "unprognostic (2.20e-1)" "unprognostic (3.77e-1)" "unprognostic (4.01e-2)" "unprognostic (1.92e-1)" "unprognostic (1.16e-1)" OTUD6A "DUBA2, FLJ25831, HSHIN6" ENSG00000189401 "OTU deubiquitinase 6A" Q7L8S5 X 70062457-70064179 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "testis: 4.5" "Cell type enriched" "Detected in some" 8 "Early primary spermatocytes: 77.8" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Testicular Germ Cell Tumor (TCGA): 4.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.1" "Not detected" "Not detected" "Testis - Spermatocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA053304 Enhanced Approved Vesicles,Cytosol NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 48: Non-specific - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 3: Early primary spermatocytes - Early meiosis" 9 Cytosol Vesicles "HPA053304: " "unprognostic (2.24e-2)" "unprognostic (1.50e-1)" OTUD6B "CGI-77, DUBA5" ENSG00000155100 "OTU deubiquitinase 6B" Q8N6M0 8 91070196-91087095 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024046, HPA024503, HPA024772" Approved Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 42 "Nucleoplasm, Golgi apparatus, Cytosol" "HPA024046: , HPA024503: , HPA024772: " "unprognostic (1.37e-3)" "potential prognostic unfavorable (1.86e-4)" "unprognostic (1.47e-1)" "unprognostic (7.55e-3)" "unprognostic (1.66e-1)" "unprognostic (1.29e-1)" "unprognostic (4.80e-2)" "unprognostic (5.58e-2)" "unprognostic (1.74e-1)" "potential prognostic unfavorable (8.35e-4)" "unprognostic (8.94e-3)" "unprognostic (7.24e-2)" "unprognostic (2.65e-2)" "unprognostic (2.91e-2)" "unprognostic (4.21e-2)" "potential prognostic unfavorable (1.66e-4)" "unprognostic (4.57e-3)" "unprognostic (2.86e-1)" "unprognostic (7.70e-2)" "potential prognostic unfavorable (2.10e-5)" "unprognostic (7.14e-3)" "unprognostic (3.17e-3)" "potential prognostic unfavorable (3.98e-5)" "potential prognostic unfavorable (3.68e-4)" "unprognostic (7.53e-3)" "unprognostic (8.56e-2)" "unprognostic (1.55e-1)" "unprognostic (2.63e-1)" "unprognostic (3.42e-1)" "unprognostic (2.79e-2)" "unprognostic (1.29e-1)" OTUD7A "C15orf16, CEZANNE2, OTUD7" ENSG00000169918 "OTU deubiquitinase 7A" Q8TE49 15 31475398-31870789 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Cancer-related genes, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.8" "Cell type enhanced" "Detected in many" "Astrocytes: 254.4;Bergmann glia: 228.7;Brain excitatory neurons: 383.8;Brain inhibitory neurons: 300.1;Distal convoluted tubule cells: 83.4;Oligodendrocyte progenitor cells: 183.8;Oligodendrocytes: 671.7;Other brain neurons: 203.9;Proximal tubule cells: 114.7;Renal connecting tubule cells: 82.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Neuroblastoma: 1.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044554 Approved Nucleoli,Cytosol NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 11: White matter - Signal transduction" "Cluster 11: Neuronal - Sensory perception" "Cluster 80: Oligodendrocytes - Myelination" 3 Cytosol Nucleoli "HPA044554: " "unprognostic (1.67e-1)" "unprognostic (2.88e-1)" "unprognostic (1.68e-3)" "unprognostic (1.14e-2)" "potential prognostic favorable (1.31e-5)" "unprognostic (3.57e-2)" OTUD7B "CEZANNE, ZA20D1" ENSG00000264522 "OTU deubiquitinase 7B" Q6GQQ9 1 149937812-150010726 "Enzymes, Predicted intracellular proteins" "Adaptive immunity, Immunity, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Melanocytes: 252.0;Oligodendrocytes: 251.3;Schwann cells: 246.2" "Cell type enhanced" "Detected in all" "oligodendrocyte: 354.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027045, HPA076357" Supported Uncertain "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 24: Non-specific - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 51: Secretory epithelial cells - Mixed function" 29 Microtubules "Cytokinetic bridge, Mitotic spindle" "HPA027045: , HPA076357: " "unprognostic (8.26e-2)" "unprognostic (2.12e-1)" "unprognostic (2.63e-1)" "unprognostic (2.53e-2)" "unprognostic (1.24e-1)" "unprognostic (1.20e-1)" "unprognostic (8.77e-2)" "unprognostic (1.90e-1)" "unprognostic (2.43e-2)" "validated prognostic favorable (4.33e-7)" "validated prognostic favorable (1.96e-4)" "unprognostic (8.64e-2)" "unprognostic (3.15e-3)" "unprognostic (8.06e-2)" "unprognostic (1.24e-1)" "unprognostic (4.09e-2)" "unprognostic (5.35e-2)" "unprognostic (3.49e-2)" "unprognostic (4.60e-3)" "unprognostic (3.81e-3)" "unprognostic (1.30e-1)" "unprognostic (2.29e-2)" "unprognostic (2.78e-1)" "unprognostic (1.23e-1)" "unprognostic (2.37e-1)" "unprognostic (1.54e-1)" "unprognostic (2.86e-2)" "unprognostic (8.81e-2)" OTULIN "FAM105B, FLJ34884" ENSG00000154124 "OTU deubiquitinase with linear linkage specificity" Q96BN8 5 14664664-14699850 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Angiogenesis, Immunity, Innate immunity, Ubl conjugation pathway, Wnt signaling pathway" "Hydrolase, Protease, Thiol protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 24.1" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051074 Uncertain Approved "Plasma membrane,Mitochondria" NA NA 3900 "Cluster 13: Non-specific - Mitochondria" "Cluster 15: Bone marrow - Innate immune response" "Cluster 25: Non-specific - Transcription" "Cluster 29: Non-specific - Unknown function" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 24 Mitochondria "Plasma membrane" "HPA051074: " "unprognostic (4.38e-2)" "unprognostic (4.35e-2)" "unprognostic (2.93e-2)" "unprognostic (1.92e-1)" "unprognostic (3.02e-1)" "unprognostic (1.56e-1)" "unprognostic (2.08e-1)" "unprognostic (7.73e-3)" "potential prognostic unfavorable (5.82e-4)" "unprognostic (4.62e-3)" "unprognostic (1.64e-1)" "unprognostic (3.16e-1)" "unprognostic (2.95e-2)" "unprognostic (2.54e-1)" "potential prognostic unfavorable (6.11e-4)" "unprognostic (1.64e-1)" "unprognostic (8.88e-2)" "unprognostic (2.39e-1)" "unprognostic (3.12e-2)" "unprognostic (1.64e-1)" "potential prognostic unfavorable (3.94e-4)" "unprognostic (3.53e-2)" "unprognostic (4.21e-3)" "unprognostic (1.84e-2)" "unprognostic (5.95e-2)" "unprognostic (2.93e-2)" "unprognostic (1.25e-1)" "unprognostic (7.51e-2)" "unprognostic (1.42e-1)" OTULINL "FAM105A, FLJ11127, NET20" ENSG00000145569 "OTU deubiquitinase with linear linkage specificity like" Q9NUU6 5 14581792-14616180 "Enzymes, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 28.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 324.9;cDC: 143.4;Early primary spermatocytes: 142.0;Hofbauer cells: 198.4;Kupffer cells: 113.8;Macrophages: 115.3;Microglia: 289.0;Monocyte progenitors: 147.9;Neutrophil progenitors: 295.9;Neutrophils: 127.6" "Cell type enriched" "Detected in many" 7 "central nervous system macrophage: 377.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Minor Salivary Gland - Macrophages, Skeletal muscle - Macrophages, Spleen - Macrophages, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046638 Uncertain Approved Nucleoli,Cytosol NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 15 "Nucleoli, Cytosol" "HPA046638: " "potential prognostic favorable (4.74e-4)" "unprognostic (2.28e-1)" "unprognostic (1.62e-2)" "unprognostic (5.80e-2)" "unprognostic (9.16e-2)" "unprognostic (1.94e-1)" "unprognostic (4.43e-2)" "unprognostic (2.97e-3)" "unprognostic (5.88e-2)" "potential prognostic favorable (5.55e-7)" "unprognostic (1.63e-3)" "unprognostic (2.41e-1)" "unprognostic (2.17e-2)" "unprognostic (1.57e-1)" "unprognostic (2.29e-1)" "unprognostic (1.90e-2)" "unprognostic (1.65e-1)" "unprognostic (4.97e-1)" "potential prognostic favorable (5.04e-5)" "unprognostic (1.22e-1)" "unprognostic (2.18e-1)" "unprognostic (4.87e-2)" "unprognostic (2.05e-3)" "unprognostic (7.42e-2)" "unprognostic (1.32e-2)" "unprognostic (9.33e-2)" "unprognostic (1.55e-1)" "unprognostic (2.85e-2)" OTX1 ENSG00000115507 "Orthodenticle homeobox 1" P32242 2 63050057-63057836 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "salivary gland: 17.4;skin 1: 8.1" "Cell type enhanced" "Detected in some" "Astrocytes: 11.2;Conjunctival goblet cells: 38.8;Ependymal cells: 8.6;Lacrimal acinar cells: 68.8;Neutrophils: 8.5;Ocular epithelial cells: 22.4;Respiratory basal cells: 21.8;Respiratory deuterosomal cells: 9.3;Respiratory ionocytes: 12.7;Respiratory secretory cells: 19.9;Salivary basal cells: 9.2;Salivary duct cells: 12.5;Salivary ionocytes: 8.7" "Cell type enhanced" "Detected in some" "astrocyte: 7.6;choroid plexus epithelial cell: 7.1;ependymal cell: 5.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 95 "neutrophil: 9.4" "Lineage enriched" "Detected in single" 95 "granulocytes: 9.4" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells (progenitors), Lung - Respiratory ciliated cells, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA052122 Uncertain Approved Nucleoplasm NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 2: Non-specific - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 5: Rhabdoid - Unknown function" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 127 Nucleoplasm "HPA052122: " "unprognostic (4.17e-1)" "unprognostic (8.51e-2)" "unprognostic (5.69e-2)" "unprognostic (2.26e-2)" "unprognostic (9.68e-2)" "unprognostic (6.81e-3)" "unprognostic (1.39e-1)" "potential prognostic unfavorable (9.59e-4)" "unprognostic (4.25e-2)" "unprognostic (6.57e-2)" "unprognostic (8.66e-2)" "validated prognostic favorable (2.47e-4)" "validated prognostic favorable (7.29e-5)" "unprognostic (1.10e-1)" "unprognostic (1.57e-3)" "unprognostic (4.67e-2)" "unprognostic (3.25e-1)" "unprognostic (2.87e-2)" "unprognostic (2.47e-3)" "unprognostic (1.59e-1)" "unprognostic (1.56e-2)" "unprognostic (2.65e-1)" "unprognostic (3.24e-2)" OTX2 ENSG00000165588 "Orthodenticle homeobox 2" P32243 14 56799905-56816693 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "choroid plexus: 151.9;retina: 259.6" "Group enriched" "Detected in some" 8 "Choroid plexus epithelial cells: 232.4;Cone photoreceptor cells: 269.1;Retinal bipolar cells: 316.8;Retinal pigment epithelial cells: 264.3;Rod photoreceptor cells: 357.2" "Group enriched" "Detected in many" 20 "choroid plexus epithelial cell: 337.2;midbrain-derived inhibitory: 238.9" "Cancer enriched" "Detected in some" 23 "Testicular Germ Cell Tumor (TCGA): 32.5" "Region enriched" "Detected in many" 8 "choroid plexus: 230.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 44.8;Brain cancer: 32.5;Uterine cancer: 29.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA000633, HPA001123" Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 1: Neuronal - Visual perception" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 4 Nucleoplasm Vesicles "HPA000633: , HPA001123: " "unprognostic (4.97e-1)" "unprognostic (1.12e-1)" "unprognostic (1.26e-2)" "unprognostic (9.90e-3)" "unprognostic (9.07e-2)" "unprognostic (3.55e-2)" OVCA2 ENSG00000262664 "OVCA2 serine hydrolase domain containing" Q8WZ82 17 2042022-2043425 "Predicted intracellular proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 165.6" "Low region specificity" "Detected in all" HPA059002 Supported Nucleoplasm,Cytosol NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 42: Non-specific - Unknown function" Nucleoplasm Cytosol "HPA059002: " "unprognostic (2.58e-1)" "unprognostic (1.17e-1)" "unprognostic (1.94e-1)" "unprognostic (5.12e-2)" "unprognostic (1.88e-2)" "unprognostic (4.49e-2)" "unprognostic (8.76e-3)" "unprognostic (5.56e-2)" "unprognostic (7.95e-2)" "unprognostic (3.89e-2)" "unprognostic (1.94e-3)" "unprognostic (6.79e-3)" "unprognostic (3.28e-2)" "unprognostic (4.83e-2)" "unprognostic (1.49e-2)" "unprognostic (3.01e-1)" "unprognostic (1.41e-1)" "unprognostic (2.09e-1)" "unprognostic (3.68e-2)" "unprognostic (2.53e-1)" "potential prognostic favorable (5.29e-4)" "unprognostic (1.31e-1)" "unprognostic (9.12e-2)" "unprognostic (4.00e-2)" "unprognostic (6.69e-2)" "unprognostic (5.83e-2)" "unprognostic (3.38e-1)" "unprognostic (2.00e-1)" "unprognostic (4.32e-1)" "unprognostic (1.92e-1)" OVCH1 OVCH ENSG00000187950 "Ovochymase 1" Q7RTY7 12 29412474-29497686 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lung: 1.4;testis: 1.1" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 21.3;Brain excitatory neurons: 20.5;Brain inhibitory neurons: 35.1;Early spermatids: 29.0;Epicardial cells: 29.6;Other brain neurons: 30.6;Retinal amacrine cells: 31.7;Vascular endothelial cells: 15.9" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Prostate - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Secreted in other tissues" Enzyme NA NA "Cluster 47: Testis - Mixed function" "Cluster 33: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 35: Neurons - Synaptic function & neurogenesis" "unprognostic (1.65e-2)" OVCH2 OVTN ENSG00000183378 "Ovochymase 2" 11 7689437-7706477 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 15 "epididymis: 177.4;retina: 85.4" "Group enriched" "Detected in many" 8 "Epididymal principal cells: 617.9;Rod photoreceptor cells: 377.2" "Cell type enhanced" "Detected in some" "midbrain-derived inhibitory: 4.9" "Cancer enhanced" "Detected in single" "Kidney Chromophobe (TCGA): 1.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 2.6;testis cancer: 2.9" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 1, Prostate - Prostate basal glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" "unprognostic (1.25e-1)" "unprognostic (1.31e-1)" "unprognostic (1.42e-1)" OVGP1 "CHIT5, MUC9" ENSG00000085465 "Oviductal glycoprotein 1" Q12889 1 111414319-111427735 "Plasma proteins, Predicted secreted proteins" Fertilization "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 135 "fallopian tube: 1950.7" "Cell type enriched" "Detected in many" 24 "Fallopian secretory cells: 3283.3" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" 11 "Ovary Serous Cystadenocarcinoma (TCGA): 40.4;Uterine Corpus Endometrial Carcinoma (TCGA): 98.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Spleen - B-cells (Spleen), Testis - Early spermatids" "Region enhanced" "Detected in many" "cerebellum: 5.9" "Low region specificity" "Detected in some" "HPA031666, HPA062205" Enhanced Supported Vesicles,Microtubules "Secreted in female reproductive system" Other NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 38: Secretory epithelial cells - Exocrine secretion" Vesicles Microtubules "HPA031666: , HPA062205: " "unprognostic (4.21e-3)" "unprognostic (3.04e-1)" "unprognostic (1.04e-1)" "unprognostic (3.64e-3)" "unprognostic (8.24e-2)" "unprognostic (2.56e-2)" "unprognostic (2.59e-1)" "unprognostic (5.46e-3)" "unprognostic (8.13e-2)" "unprognostic (1.16e-3)" "unprognostic (9.86e-2)" "unprognostic (7.95e-2)" "unprognostic (2.13e-2)" "unprognostic (2.86e-2)" "unprognostic (9.67e-2)" "unprognostic (1.68e-1)" "unprognostic (4.58e-1)" "unprognostic (7.53e-2)" "unprognostic (1.30e-1)" "unprognostic (1.24e-2)" "unprognostic (1.03e-1)" "unprognostic (2.20e-1)" "unprognostic (2.44e-2)" "unprognostic (6.84e-2)" "unprognostic (2.71e-1)" "unprognostic (1.05e-1)" "unprognostic (1.41e-1)" OVOL1 HOVO1 ENSG00000172818 "Ovo like transcriptional repressor 1" O14753 11 65787063-65797214 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 55.4;skin 1: 49.1;testis: 33.8" "Cell type enhanced" "Detected in many" "Breast secretory cells: 143.1;Endometrial luminal cells: 162.7;Epididymal basal cells: 145.3;Esophageal apical cells: 604.2;Esophageal suprabasal cells: 233.0;Late primary spermatocytes: 191.9;Late spermatids: 137.8;Ocular epithelial cells: 158.3;Syncytiotrophoblasts: 392.4;Urothelial cells: 243.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA003984 Uncertain Approved Nucleoplasm Yes NA "Cluster 39: Testis - Nuclear processes" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 5 Nucleoplasm "HPA003984: " "unprognostic (9.27e-3)" "unprognostic (1.38e-2)" "unprognostic (4.36e-2)" "unprognostic (2.39e-1)" "unprognostic (2.05e-1)" "unprognostic (1.64e-3)" "unprognostic (1.77e-1)" "unprognostic (2.70e-1)" "validated prognostic favorable (1.95e-7)" "validated prognostic favorable (1.53e-4)" "potential prognostic favorable (1.84e-5)" "unprognostic (1.96e-1)" "unprognostic (1.45e-3)" "unprognostic (5.03e-3)" "unprognostic (2.37e-1)" "unprognostic (1.66e-1)" "unprognostic (1.48e-2)" "unprognostic (2.27e-2)" "unprognostic (3.54e-3)" "unprognostic (1.65e-2)" "unprognostic (3.31e-1)" "unprognostic (7.20e-2)" "unprognostic (2.19e-1)" "unprognostic (4.94e-2)" "unprognostic (5.27e-2)" "unprognostic (1.37e-1)" "unprognostic (1.41e-1)" "unprognostic (1.46e-1)" OVOL2 "bA504H3.3, CHED, CHED1, HOVO2, ZNF339" ENSG00000125850 "Ovo like zinc finger 2" Q9BRP0 20 17956979-18059188 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Corneal dystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 6.7;stomach 1: 7.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 204.3;Respiratory ciliated cells: 117.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Gonadotropes, Stomach - Gastric mucous cells, Testis - Early spermatids" "Region enhanced" "Detected in many" "cerebral cortex: 10.3" "Group enriched" "Detected in some" 5 "cerebral cortex: 5.3;hippocampal formation: 4.3" HPA038531 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 60: Stomach - Digestion" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 16 Nucleoplasm Cytosol "HPA038531: " "unprognostic (1.06e-1)" "unprognostic (7.10e-2)" "unprognostic (1.19e-1)" "potential prognostic favorable (7.16e-4)" "unprognostic (9.11e-2)" "unprognostic (1.43e-2)" "unprognostic (4.86e-2)" "unprognostic (3.91e-2)" "unprognostic (9.60e-2)" "unprognostic (1.47e-2)" "unprognostic (1.99e-2)" "unprognostic (3.69e-1)" "unprognostic (6.98e-2)" "unprognostic (5.80e-2)" "unprognostic (3.09e-2)" "unprognostic (1.41e-2)" "unprognostic (3.64e-2)" "unprognostic (1.80e-1)" "unprognostic (1.90e-2)" "unprognostic (3.18e-1)" "unprognostic (1.34e-1)" "unprognostic (4.16e-2)" OVOL3 HOVO3 ENSG00000105261 "Ovo like zinc finger 3" O00110 19 36111143-36113711 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 4 "testis: 3.6" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 6.2;Early primary spermatocytes: 3.1;Müller glia: 2.1;Myonuclei: 2.2;Plasma cells: 3.0;Respiratory ionocytes: 5.1;Rod photoreceptor cells: 3.3;Tuft cells: 11.5" "Cell type enhanced" "Detected in some" "oligodendrocyte: 2.3" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA047540 Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 47: Testis - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 44: Plasma cells - Antibody production & secretion" Nucleoplasm "Vesicles, Cytosol" "HPA047540: " "unprognostic (2.79e-1)" "unprognostic (1.63e-1)" "unprognostic (1.58e-1)" OXA1L "MGC133129, OXA1, OXA1L1" ENSG00000155463 "OXA1L mitochondrial inner membrane protein" Q15070 14 22766522-22773042 "Essential proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 181.1;Hofbauer cells: 182.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003531 Approved Supported Mitochondria NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 52: Non-specific - Cellular respiration" "Cluster 44: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 15: Non-specific - Protein processing" 6 Mitochondria "HPA003531: " "unprognostic (3.15e-1)" "unprognostic (2.52e-1)" "unprognostic (7.29e-2)" "unprognostic (1.96e-1)" "unprognostic (6.91e-3)" "unprognostic (2.63e-1)" "unprognostic (6.79e-2)" "unprognostic (7.55e-3)" "unprognostic (3.09e-3)" "potential prognostic unfavorable (3.86e-4)" "potential prognostic favorable (3.03e-9)" "unprognostic (9.18e-3)" "unprognostic (1.53e-2)" "unprognostic (1.00e-3)" "unprognostic (5.92e-3)" "unprognostic (1.90e-2)" "unprognostic (3.97e-3)" "unprognostic (1.67e-2)" "unprognostic (8.76e-3)" "unprognostic (5.83e-2)" "unprognostic (2.82e-1)" "unprognostic (6.09e-2)" "unprognostic (1.79e-1)" "unprognostic (7.79e-2)" "unprognostic (8.86e-3)" "unprognostic (2.02e-2)" "unprognostic (3.49e-1)" "unprognostic (7.32e-2)" "unprognostic (1.06e-1)" "unprognostic (2.12e-1)" "unprognostic (2.59e-1)" OXCT1 "OXCT, SCOT" ENSG00000083720 "3-oxoacid CoA-transferase 1" P55809 5 41730065-41870425 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 230.2" "Cell type enhanced" "Detected in many" "Epididymal clear cells: 534.8;Parietal cells: 265.2" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 6 "Kidney Chromophobe (TCGA): 190.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Skin - Mitotic cells (Skin), Stomach - Parietal cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012047, HPA061425" Enhanced Enhanced Mitochondria NA NA 660000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 35: Non-specific - Mixed function" "Cluster 14: Neurons - Synaptic function" "Cluster 29: Non-specific - Unknown function" "Cluster 9: T-cells - Adaptive immunity: Regulation" 10 Mitochondria "HPA012047: , HPA061425: " "unprognostic (1.48e-1)" "unprognostic (5.54e-2)" "unprognostic (7.97e-2)" "unprognostic (1.18e-2)" "unprognostic (1.31e-1)" "unprognostic (5.66e-3)" "unprognostic (1.91e-1)" "unprognostic (3.80e-2)" "unprognostic (7.03e-2)" "unprognostic (2.94e-1)" "potential prognostic favorable (5.36e-6)" "unprognostic (9.09e-3)" "unprognostic (2.71e-2)" "potential prognostic unfavorable (3.00e-4)" "unprognostic (8.96e-2)" "unprognostic (1.13e-1)" "unprognostic (2.59e-2)" "unprognostic (5.34e-2)" "unprognostic (2.84e-2)" "unprognostic (1.82e-1)" "unprognostic (2.32e-1)" "unprognostic (6.39e-3)" "unprognostic (3.67e-1)" "unprognostic (1.56e-1)" "unprognostic (1.78e-1)" "unprognostic (1.69e-1)" "potential prognostic unfavorable (3.18e-5)" "unprognostic (9.33e-2)" "unprognostic (6.18e-2)" "potential prognostic unfavorable (3.23e-4)" "unprognostic (9.36e-2)" OXCT2 "FKSG25, FLJ00030, SCOT-T" ENSG00000198754 "3-oxoacid CoA-transferase 2" Q9BYC2 1 39769523-39771348 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "testis: 69.6" "Cell type enhanced" "Detected in single" "Late spermatids: 2.0" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 8.9" "Pituitary gland - Corticotropes, Skin - Hair cortex cells, Skin - Inner root sheath cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA075423 Enhanced NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 23: Testis - Spermatogenesis" "Cluster 30: White matter - Myelination" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 16 "HPA075423: " "unprognostic (6.69e-2)" "unprognostic (1.24e-1)" "unprognostic (4.31e-2)" "unprognostic (3.32e-1)" "potential prognostic favorable (6.90e-4)" "unprognostic (1.11e-2)" "unprognostic (1.75e-2)" "unprognostic (7.59e-2)" "unprognostic (5.48e-2)" "unprognostic (1.88e-1)" OXER1 "GPCR, GPR170, TG1019" ENSG00000162881 "Oxoeicosanoid receptor 1" Q8TDS5 2 42762499-42764135 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 56.4" "Cell type enhanced" "Detected in some" "Enteric stem cells: 4.6;Enteric transient amplifying cells: 4.9;Enterocytes: 14.2;Hepatocytes: 10.5;Melanocytes: 5.1;Microglia: 4.3;Neutrophils: 5.1;Platelets: 4.2;Proximal tubule cells: 7.5;Retinal amacrine cells: 5.4" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 5.2;choroid plexus epithelial cell: 2.4;fibroblast: 1.8" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 16.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 73.5;eosinophil: 158.2" "Lineage enriched" "Detected in many" 81 "granulocytes: 158.2" "Cancer enhanced" "Detected in some" "liver cancer: 2.7" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" HPA051433 Approved NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 23: Choroid plexus - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 31 "HPA051433: " "unprognostic (6.32e-2)" "unprognostic (3.48e-1)" "unprognostic (1.08e-2)" "unprognostic (3.70e-2)" "unprognostic (7.08e-2)" "unprognostic (6.68e-3)" "unprognostic (3.25e-2)" "unprognostic (2.71e-2)" "potential prognostic unfavorable (3.33e-5)" "unprognostic (2.51e-1)" "unprognostic (2.23e-3)" "unprognostic (7.55e-2)" "unprognostic (1.57e-1)" "unprognostic (2.40e-1)" "unprognostic (5.45e-2)" "potential prognostic favorable (3.84e-4)" "unprognostic (4.80e-2)" "potential prognostic favorable (6.76e-4)" "unprognostic (9.35e-2)" "unprognostic (7.89e-2)" "unprognostic (5.38e-2)" "unprognostic (6.29e-2)" "unprognostic (8.94e-2)" OXGR1 "aKGR, GPR80, GPR99, P2RY15, P2Y15" ENSG00000165621 "Oxoglutarate receptor 1" Q96P68 13 96985713-96994730 "G-protein coupled receptors, Predicted membrane proteins" "Immunity, Innate immunity" "G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "breast: 2.8" "Cell type enhanced" "Detected in some" "Extravillous trophoblasts: 71.2;Lacrimal acinar cells: 7.2;Lymphatic endothelial cells: 6.7;Migrating cytotrophoblasts: 15.8;Paneth cells: 7.7;Renal collecting duct intercalated cells: 22.1" "Cell type enhanced" "Detected in some" "mammillary body: 3.8" "Cancer enriched" "Detected in many" 4 "Kidney Chromophobe (TCGA): 21.3" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.3" "Lineage enriched" "Detected in single" 14 "dendritic cells: 1.3" "Cancer enhanced" "Detected in some" "colorectal cancer: 2.9;Rhabdoid: 5.3" "Adipose subcutaneous - Smooth muscle cells, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Beta cells, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" HPA067673 Supported "Plasma membrane" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 38: Sub-cortical - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" "Plasma membrane" "HPA067673: " "unprognostic (1.25e-1)" "unprognostic (1.67e-1)" "unprognostic (2.81e-1)" "unprognostic (7.82e-2)" "unprognostic (3.13e-1)" "unprognostic (7.17e-2)" "unprognostic (1.85e-2)" "unprognostic (2.31e-1)" "unprognostic (5.01e-1)" "unprognostic (1.78e-1)" "unprognostic (4.88e-1)" "unprognostic (2.65e-2)" "unprognostic (2.45e-1)" "unprognostic (1.82e-2)" "unprognostic (1.17e-1)" OXLD1 "C17orf90, MGC104712" ENSG00000204237 "Oxidoreductase like domain containing 1" Q5BKU9 17 81665036-81666635 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 191.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056878, HPA057019" Uncertain Approved Vesicles,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 97: Non-specific - Cellular respiration" "Vesicles, Cytosol" "HPA056878: , HPA057019: " "unprognostic (3.18e-2)" "unprognostic (3.94e-1)" "potential prognostic favorable (5.61e-4)" "unprognostic (9.59e-2)" "unprognostic (1.19e-1)" "unprognostic (5.38e-2)" "unprognostic (1.25e-1)" "unprognostic (3.52e-1)" "unprognostic (2.33e-1)" "validated prognostic unfavorable (8.58e-5)" "validated prognostic unfavorable (5.39e-4)" "unprognostic (9.13e-2)" "unprognostic (1.89e-3)" "unprognostic (1.76e-1)" "unprognostic (1.53e-1)" "unprognostic (1.11e-2)" "unprognostic (6.04e-2)" "unprognostic (1.67e-2)" "unprognostic (2.31e-1)" "unprognostic (1.17e-1)" "unprognostic (2.97e-1)" "unprognostic (2.37e-3)" "unprognostic (1.33e-1)" "unprognostic (1.53e-1)" "unprognostic (2.39e-2)" "unprognostic (3.74e-1)" "unprognostic (1.45e-1)" OXNAD1 MGC15763 ENSG00000154814 "Oxidoreductase NAD binding domain containing 1" Q96HP4 3 16265160-16350299 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Innate lymphoid cells: 173.5;NK-cells: 186.3;T-cells: 335.9" "Cell type enhanced" "Detected in all" "leukocyte: 322.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 81.2" "Lineage enriched" "Detected in all" 4 "T-cells: 81.2" "Low cancer specificity" "Detected in all" "Colon - T-cells, Prostate - T-cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036830, HPA059160" Approved Approved Nucleoplasm NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 53: Neurons - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 9: T-cells - Adaptive immunity: Regulation" 3 Nucleoplasm "HPA036830: , HPA059160: " "unprognostic (1.19e-2)" "unprognostic (1.19e-1)" "unprognostic (2.51e-1)" "unprognostic (1.74e-1)" "unprognostic (1.37e-1)" "unprognostic (2.77e-1)" "unprognostic (4.37e-2)" "unprognostic (3.55e-3)" "unprognostic (8.63e-2)" "unprognostic (5.30e-2)" "potential prognostic favorable (1.22e-4)" "unprognostic (3.77e-1)" "potential prognostic favorable (3.14e-4)" "unprognostic (1.47e-1)" "unprognostic (5.70e-2)" "unprognostic (2.69e-1)" "unprognostic (9.54e-2)" "unprognostic (6.34e-2)" "unprognostic (3.06e-1)" "unprognostic (3.45e-1)" "unprognostic (5.21e-2)" "unprognostic (1.50e-1)" "unprognostic (1.26e-1)" "unprognostic (2.03e-1)" "unprognostic (3.15e-3)" "unprognostic (1.21e-1)" "unprognostic (1.29e-1)" "unprognostic (2.15e-1)" "unprognostic (1.11e-1)" "unprognostic (1.03e-1)" "unprognostic (3.00e-1)" OXR1 TLDC3 ENSG00000164830 "Oxidation resistance 1" Q8N573 8 106270144-106752694 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Stress response" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Loop of henle epithelial cells: 1092.6;Microglia: 1319.2;Renal collecting duct intercalated cells: 1234.6;Retinal amacrine cells: 1346.0;Rod photoreceptor cells: 2238.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027375, HPA027380, HPA027395" Enhanced Approved Vesicles NA NA 6500 "Cluster 42: Non-specific - Vesicular transport" "Cluster 40: Non-specific - Mixed function" "Cluster 14: Neurons - Synaptic function" "Cluster 40: Non-specific - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" 1 Vesicles "HPA027375: , HPA027380: , HPA027395: " "unprognostic (1.24e-1)" "unprognostic (1.65e-2)" "unprognostic (6.53e-2)" "unprognostic (1.80e-2)" "unprognostic (2.87e-1)" "unprognostic (4.03e-2)" "unprognostic (1.79e-2)" "unprognostic (1.54e-1)" "unprognostic (5.29e-2)" "unprognostic (8.52e-3)" "potential prognostic favorable (3.71e-5)" "unprognostic (3.33e-2)" "unprognostic (1.65e-1)" "unprognostic (2.63e-1)" "unprognostic (4.31e-1)" "unprognostic (8.43e-2)" "unprognostic (4.64e-2)" "unprognostic (3.85e-2)" "unprognostic (2.28e-2)" "unprognostic (6.84e-2)" "unprognostic (2.67e-3)" "potential prognostic unfavorable (7.53e-4)" "unprognostic (1.01e-1)" "unprognostic (6.77e-2)" "unprognostic (4.73e-2)" "unprognostic (2.60e-1)" "unprognostic (1.54e-2)" "unprognostic (1.31e-1)" "unprognostic (2.28e-1)" "unprognostic (1.43e-1)" "unprognostic (2.04e-1)" OXSM "CEM1, FASN2D, FLJ20604, KS" ENSG00000151093 "3-oxoacyl-ACP synthase, mitochondrial" Q9NWU1 3 25782917-25794534 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Cardiomyocytes: 268.3;Early spermatids: 167.8;Epicardial cells: 75.0;Late primary spermatocytes: 139.6;Late spermatids: 147.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Spleen - B-cells (Spleen), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021293, HPA021300, HPA021337" Enhanced Approved Mitochondria,Cytosol No No 10000 "Cluster 33: Non-specific - ATP binding" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 5 "Mitochondria, Cytosol" "HPA021293: , HPA021300: , HPA021337: " "unprognostic (1.37e-1)" "unprognostic (5.58e-3)" "unprognostic (6.13e-2)" "unprognostic (1.34e-1)" "unprognostic (1.55e-2)" "unprognostic (1.10e-2)" "unprognostic (3.76e-1)" "potential prognostic favorable (3.89e-4)" "unprognostic (5.54e-2)" "unprognostic (3.02e-3)" "potential prognostic favorable (6.68e-11)" "unprognostic (9.74e-3)" "unprognostic (6.91e-3)" "unprognostic (7.34e-3)" "unprognostic (1.39e-1)" "unprognostic (2.17e-1)" "unprognostic (1.14e-1)" "unprognostic (2.10e-1)" "unprognostic (4.53e-2)" "unprognostic (1.01e-1)" "unprognostic (4.41e-2)" "unprognostic (2.76e-1)" "unprognostic (2.55e-1)" "unprognostic (7.22e-2)" "potential prognostic favorable (9.26e-4)" "unprognostic (6.88e-2)" "unprognostic (3.52e-2)" "unprognostic (4.80e-2)" "unprognostic (2.51e-1)" "unprognostic (4.49e-2)" "unprognostic (2.58e-1)" OXSR1 "KIAA1101, OSR1" ENSG00000172939 "Oxidative stress responsive kinase 1" O95747 3 38165089-38255484 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 510.3;monocytes: 613.4;Neutrophils: 1659.8;Ocular epithelial cells: 430.9;Urothelial cells: 521.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008237, CAB017181" Supported Supported Cytosol NA NA 270000 "Cluster 25: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 58 Cytosol "CAB017181: , HPA008237: " "unprognostic (1.36e-2)" "unprognostic (1.81e-1)" "unprognostic (2.92e-1)" "unprognostic (6.34e-3)" "unprognostic (2.55e-1)" "unprognostic (3.99e-1)" "unprognostic (1.14e-1)" "unprognostic (1.04e-1)" "unprognostic (3.39e-2)" "potential prognostic unfavorable (2.35e-4)" "potential prognostic favorable (7.65e-6)" "unprognostic (8.62e-3)" "unprognostic (7.61e-2)" "unprognostic (1.10e-3)" "unprognostic (1.24e-3)" "unprognostic (8.37e-2)" "potential prognostic unfavorable (5.56e-4)" "unprognostic (9.74e-2)" "unprognostic (9.21e-2)" "unprognostic (1.68e-1)" "unprognostic (2.82e-2)" "unprognostic (5.83e-3)" "unprognostic (1.79e-2)" "unprognostic (2.41e-3)" "unprognostic (5.76e-2)" "unprognostic (1.06e-2)" "unprognostic (3.29e-1)" "unprognostic (2.62e-1)" "unprognostic (2.02e-1)" "unprognostic (6.48e-2)" "unprognostic (2.17e-2)" OXT "OT, OT-NPI, OXT-NPI" ENSG00000101405 "Oxytocin/neurophysin I prepropeptide" P01178 20 3071620-3072517 "Plasma proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 153 "brain: 2931.7" "Cell type enriched" "Detected in some" 7 "Other brain neurons: 1009.0" "Group enriched" "Detected in many" 5 "splatter: 16.0;upper rhombic lip: 11.5" "Cancer enriched" "Detected in some" 4 "Testicular Germ Cell Tumor (TCGA): 16.4" "Region enriched" "Detected in many" 144 "hypothalamus: 2524.3" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in single" 4 "Gastric cancer: 1.5" "Adipose subcutaneous - Adipocytes (Subcutaneous), Kidney - Proximal tubular cells" "Region enriched" "Detected in many" 6 "hypothalamus: 179.4" "Group enriched" "Detected in some" 892 "basal ganglia: 866.7;hypothalamus: 2049.5" HPA071892 Supported Supported "Secreted to blood" Hormone NA NA 1500000 230000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 36: Brain & Liver - Signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 18: Liver cancer - Metabolism" "Cluster 109: Neurons - Neuronal signaling" 1 "HPA071892: " "unprognostic (1.78e-1)" "unprognostic (1.96e-1)" "unprognostic (5.68e-2)" "unprognostic (8.30e-2)" "unprognostic (1.31e-1)" "unprognostic (7.70e-2)" "unprognostic (3.74e-1)" OXTR OTR ENSG00000180914 "Oxytocin receptor" P30559 3 8750381-8769628 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "breast: 50.5" "Cell type enriched" "Detected in some" 9 "Breast myoepithelial cells: 577.8" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 9.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 72: Neuronal - Signal transduction" "Cluster 62: Smooth muscle cells - Muscle contraction" "unprognostic (1.70e-3)" "unprognostic (1.51e-1)" "unprognostic (3.33e-2)" "unprognostic (6.41e-2)" "unprognostic (6.02e-2)" "unprognostic (3.87e-3)" "unprognostic (1.46e-1)" "unprognostic (8.40e-3)" "unprognostic (4.98e-2)" "unprognostic (1.79e-1)" "unprognostic (9.55e-2)" "unprognostic (9.41e-2)" "unprognostic (4.93e-3)" "unprognostic (1.18e-3)" "unprognostic (1.71e-1)" "unprognostic (2.19e-1)" "unprognostic (4.83e-1)" "unprognostic (2.80e-2)" "unprognostic (4.27e-2)" "unprognostic (3.79e-2)" "unprognostic (4.84e-2)" "unprognostic (3.32e-2)" P2RX1 P2X1 ENSG00000108405 "Purinergic receptor P2X 1" P51575 17 3896592-3916476 "Predicted membrane proteins" "Apoptosis, Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 150.2;pancreas: 61.4;urinary bladder: 82.5" "Cell type enhanced" "Detected in some" "Hematopoietic stem cells: 117.4;Mast cells: 240.6;Megakaryocyte progenitors: 93.7;Megakaryocyte-Erythroid progenitors: 142.0;Megakaryocytes: 111.3;Monocyte progenitors: 91.3;monocytes: 75.8;Neutrophil progenitors: 180.1;Neutrophils: 195.8;pDCs: 193.3;Plasma cells: 135.0;Platelets: 508.7;Smooth muscle cells: 253.8;Thymocytes: 120.3" "Group enriched" "Detected in some" 4 "central nervous system macrophage: 14.2;leukocyte: 21.4;vascular associated smooth muscle cell: 7.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 46.5" "Group enriched" "Detected in many" 30 "dendritic cells: 15.2;granulocytes: 23.6;monocytes: 46.5" "Group enriched" "Detected in some" 9 "Leukemia: 14.1;Myeloma: 15.5" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Minor Salivary Gland - Plasma cells, Prostate - Smooth muscle cells" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "midbrain: 1.8" HPA057678 Approved "Endoplasmic reticulum" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 46: Brainstem - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 4 "Endoplasmic reticulum" "HPA057678: " "unprognostic (9.25e-3)" "unprognostic (6.95e-2)" "unprognostic (4.09e-3)" "unprognostic (2.79e-2)" "potential prognostic favorable (1.04e-4)" "unprognostic (2.03e-2)" "unprognostic (7.35e-3)" "unprognostic (1.23e-1)" "unprognostic (2.86e-1)" "unprognostic (2.51e-2)" "unprognostic (3.11e-2)" "unprognostic (1.30e-1)" "unprognostic (2.97e-1)" "unprognostic (1.01e-1)" P2RX2 "DFNA41, P2X2" ENSG00000187848 "Purinergic receptor P2X 2" Q9UBL9 12 132618776-132622388 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Hearing, Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.3;epididymis: 20.6;prostate: 14.1" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 3.1;Breast lactating cells: 17.8;Endometrial ciliated cells: 2.6;Epididymal basal cells: 2.6;Epididymal efferent duct ciliated cells: 5.5;Fibroblasts: 7.6;Oocytes: 4.6;pDCs: 1.9;Peritubular myoid cells: 2.4;Smooth muscle cells: 2.7" "Cell type enhanced" "Detected in some" "amygdala excitatory: 8.7;hippocampal dentate gyrus: 24.9" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 2.5" "Group enriched" "Detected in many" 6 "amygdala: 19.3;cerebral cortex: 23.1;hippocampal formation: 21.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 3.8" "Colon - Fibroblasts, Pituitary gland - Thyrotropes, Stomach - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 29: Forebrain - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" 1 "unprognostic (2.66e-1)" "unprognostic (2.68e-1)" "unprognostic (6.15e-2)" "unprognostic (2.52e-1)" "unprognostic (7.46e-3)" P2RX3 P2X3 ENSG00000109991 "Purinergic receptor P2X 3" P56373 11 57338352-57372396 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 3.9;liver: 1.6;testis: 3.1" "Group enriched" "Detected in some" 4 "Early spermatids: 98.8;Late spermatids: 39.7" "Cell type enhanced" "Detected in some" "pericyte: 3.4;vascular associated smooth muscle cell: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Neuroblastoma: 24.4" "Colon - Colon enteroendocrine cells, Liver - Hepatocytes, Testis - Late spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA057776 Uncertain NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "HPA057776: " P2RX4 P2X4 ENSG00000135124 "Purinergic receptor P2X 4" Q99571 12 121210065-121234106 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 129.2;Cytotrophoblasts: 177.3;Enterocytes: 137.8;Goblet cells: 156.5;Hofbauer cells: 171.8;Migrating cytotrophoblasts: 201.3;monocytes: 148.7;Syncytiotrophoblasts: 205.0" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 108.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039494 Enhanced NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 60: Stomach - Digestion" "Cluster 25: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 13 "HPA039494: " "unprognostic (3.44e-1)" "unprognostic (1.36e-1)" "unprognostic (4.16e-1)" "unprognostic (4.26e-1)" "unprognostic (3.34e-2)" "unprognostic (6.58e-2)" "unprognostic (3.20e-2)" "unprognostic (7.98e-2)" "unprognostic (2.59e-2)" "unprognostic (5.34e-2)" "potential prognostic favorable (6.10e-5)" "unprognostic (2.70e-2)" "unprognostic (1.63e-2)" "potential prognostic unfavorable (3.43e-5)" "unprognostic (8.97e-3)" "unprognostic (2.26e-1)" "unprognostic (2.68e-1)" "unprognostic (4.76e-3)" "unprognostic (7.02e-2)" "unprognostic (1.41e-1)" "unprognostic (4.07e-2)" "unprognostic (1.64e-1)" "unprognostic (2.18e-2)" "unprognostic (1.81e-1)" "unprognostic (1.90e-1)" "unprognostic (2.25e-2)" "unprognostic (9.56e-2)" "unprognostic (1.44e-2)" "unprognostic (3.76e-2)" "unprognostic (3.52e-1)" "unprognostic (1.96e-1)" P2RX5 "LRH-1, P2X5" ENSG00000083454 "Purinergic receptor P2X 5" Q93086 17 3672199-3696240 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 23.7;lymphoid tissue: 73.8" "Cell type enhanced" "Detected in some" "B-cells: 1.7;Megakaryocyte-Erythroid progenitors: 1.3;Plasma cells: 1.2;Thymic myoid cells: 1.4" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 19 "memory B-cell: 76.8;naive B-cell: 85.6" "Lineage enriched" "Detected in many" 20 "B-cells: 85.6" "Cancer enhanced" "Detected in many" "lymphoma: 68.0" "Breast - Plasma cells, Lung - B-cells (Lung), Minor Salivary Gland - Plasma cells, Spleen - B-cells (Spleen), Thyroid gland - Plasma cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021948, HPA067827" Supported Approved "Plasma membrane,Cytosol" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 24: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 1 "Plasma membrane, Cytosol" "HPA021948: , HPA067827: " "unprognostic (1.60e-1)" "unprognostic (7.73e-2)" "unprognostic (2.65e-3)" "unprognostic (3.79e-2)" "unprognostic (1.40e-1)" "unprognostic (2.40e-1)" "unprognostic (1.00e-1)" "unprognostic (3.33e-2)" "unprognostic (2.18e-1)" "unprognostic (3.08e-2)" "unprognostic (3.36e-2)" "unprognostic (2.42e-1)" "potential prognostic unfavorable (3.97e-6)" "unprognostic (2.44e-2)" "unprognostic (1.82e-2)" "unprognostic (1.87e-1)" "unprognostic (9.76e-3)" P2RX6 "MGC129625, P2RXL1, P2X6, P2XM" ENSG00000099957 "Purinergic receptor P2X 6" O15547 22 21009808-21028013 "Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 31.7;tongue: 11.1" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 16.0;Corticotrophs: 16.3;Epididymal basal cells: 11.8;Myonuclei: 55.3;Myosatellite cells: 31.1;Retinal ganglion cells: 27.0;Sertoli cells: 14.5" "Cell type enhanced" "Detected in many" "mammillary body: 26.5" "Cancer enhanced" "Detected in single" "Skin Cutaneous Melanoma (TCGA): 1.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 5.3" "Liver - Hepatic stellate cells, Stomach - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA028776, HPA028777" Approved Approved Nucleoli,Cytosol NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 24: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 40 "Nucleoli, Cytosol" "HPA028776: , HPA028777: " "unprognostic (3.70e-2)" "unprognostic (3.57e-3)" "unprognostic (8.05e-2)" P2RX7 "MGC20089, P2X7" ENSG00000089041 "Purinergic receptor P2X 7" Q99572 12 121132819-121188032 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.8" "Cell type enhanced" "Detected in many" "cDC: 108.6;Macrophages: 84.3;Melanocytes: 194.7;Microglia: 151.5;monocytes: 81.3;Oligodendrocyte progenitor cells: 187.4;Oligodendrocytes: 350.2" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 481.6;oligodendrocyte: 312.9" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 30.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 2.9;gdT-cell: 1.3;intermediate monocyte: 4.5;myeloid DC: 2.6;non-classical monocyte: 3.3;T-reg: 1.4" "Group enriched" "Detected in many" 5 "dendritic cells: 2.6;monocytes: 4.5;T-cells: 1.4" "Cancer enhanced" "Detected in many" "Myeloma: 15.3;skin cancer: 12.8" "Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034968, HPA042013, HPA044141" Approved NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 10 "HPA034968: , HPA042013: , HPA044141: " "unprognostic (3.17e-2)" "unprognostic (1.27e-2)" "unprognostic (7.01e-2)" "unprognostic (8.34e-3)" "unprognostic (3.64e-2)" "unprognostic (1.35e-1)" "unprognostic (1.80e-1)" "unprognostic (2.92e-3)" "unprognostic (1.95e-2)" "unprognostic (4.34e-2)" "unprognostic (1.66e-1)" "unprognostic (5.54e-2)" "unprognostic (1.98e-2)" "unprognostic (3.39e-1)" "unprognostic (4.37e-3)" "unprognostic (3.16e-2)" "unprognostic (2.14e-1)" "unprognostic (9.47e-2)" "unprognostic (1.14e-1)" "unprognostic (8.89e-2)" "unprognostic (3.57e-1)" "unprognostic (3.81e-2)" "unprognostic (8.99e-3)" "unprognostic (1.23e-3)" "unprognostic (1.59e-2)" "unprognostic (7.18e-2)" "unprognostic (9.50e-3)" "unprognostic (2.12e-1)" P2RY1 "P2Y1, SARCC" ENSG00000169860 "Purinergic receptor P2Y1" P47900 3 152835131-152841439 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Blood coagulation, Hemostasis" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 23.9" "Cell type enhanced" "Detected in many" "Astrocytes: 47.7;Esophageal suprabasal cells: 46.5;Kupffer cells: 41.0;Megakaryocyte progenitors: 36.1;Megakaryocytes: 49.5;Pituicytes/FSCs: 113.5;Platelets: 202.4;Prostatic glandular cells: 65.5;Retinal amacrine cells: 39.2" "Group enriched" "Detected in many" 5 "astrocyte: 47.6;Bergmann glia: 21.9;ependymal cell: 26.3;fibroblast: 26.3;medium spiny neuron: 25.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 6.0;non-classical monocyte: 2.7" "Group enriched" "Detected in many" 9 "granulocytes: 6.0;monocytes: 2.7" "Cancer enhanced" "Detected in many" "cervical cancer: 9.6;Gallbladder cancer: 11.3" "Adipose subcutaneous - Macrophages, Colon - Enteric glia cells, Skeletal muscle - Skeletal myocytes, Skin - Keratinocyte (other), Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015577 Enhanced NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 33: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 26 "HPA015577: " "unprognostic (3.05e-1)" "unprognostic (1.79e-1)" "unprognostic (9.81e-2)" "unprognostic (4.03e-2)" "unprognostic (2.24e-2)" "unprognostic (1.63e-1)" "potential prognostic unfavorable (7.76e-6)" "unprognostic (2.96e-3)" "potential prognostic favorable (2.89e-4)" "unprognostic (1.78e-2)" "unprognostic (1.81e-1)" "unprognostic (9.05e-3)" "unprognostic (1.14e-2)" "unprognostic (2.21e-2)" "unprognostic (4.39e-2)" "unprognostic (9.40e-2)" "unprognostic (2.60e-1)" "unprognostic (2.11e-1)" "unprognostic (8.00e-2)" "unprognostic (1.65e-1)" "unprognostic (9.45e-2)" "unprognostic (1.38e-1)" P2RY10 P2Y10 ENSG00000078589 "P2Y receptor family member 10" O00398 X 78945332-78963727 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 25.7" "Group enriched" "Detected in some" 5 "B-cells: 119.2;cDC: 41.0;Innate lymphoid cells: 44.7;NK-cells: 48.2;Plasma cells: 64.3;T-cells: 107.4" "Cell type enriched" "Detected in some" 39 "leukocyte: 43.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 256.9" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 17 "Leukemia: 4.9;lymphoma: 14.7;Myeloma: 17.4" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Spleen - B-cells (Spleen), Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA036757, HPA065766" Enhanced NA NA "Cluster 32: Basophils - Transcription" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 9: Non-specific - Receptor signaling" "Cluster 55: Lymphoma - Immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 3 "HPA036757: , HPA065766: " "unprognostic (3.74e-2)" "unprognostic (2.30e-2)" "unprognostic (1.03e-1)" "unprognostic (1.27e-2)" "unprognostic (1.41e-1)" "unprognostic (1.79e-1)" "unprognostic (2.96e-1)" "potential prognostic favorable (7.98e-5)" "unprognostic (1.75e-1)" "unprognostic (2.58e-1)" "unprognostic (3.75e-2)" "unprognostic (4.06e-3)" "unprognostic (7.36e-2)" "unprognostic (1.91e-2)" "unprognostic (3.90e-1)" "unprognostic (8.66e-2)" "unprognostic (1.80e-1)" "unprognostic (3.07e-2)" "unprognostic (2.89e-1)" "unprognostic (3.98e-2)" P2RY11 P2Y11 ENSG00000244165 "Purinergic receptor P2Y11" Q96G91 19 10111693-10115372 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Microglia: 11.5;NK-cells: 16.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 18.9" "Group enriched" "Detected in many" 5 "NK-cells: 13.9;T-cells: 18.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014232 Approved NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 15: Non-specific - Transcription" "Cluster 23: Non-specific - Transcription" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" "HPA014232: " "unprognostic (3.92e-2)" "unprognostic (1.09e-1)" "unprognostic (4.86e-2)" "unprognostic (2.27e-1)" "unprognostic (9.95e-3)" "unprognostic (1.08e-1)" "unprognostic (1.63e-1)" "unprognostic (1.01e-2)" "unprognostic (7.07e-2)" "unprognostic (1.96e-1)" "unprognostic (1.27e-3)" "unprognostic (2.43e-3)" "unprognostic (1.20e-2)" "unprognostic (2.11e-1)" "unprognostic (1.18e-1)" "unprognostic (3.52e-2)" "unprognostic (4.67e-2)" "unprognostic (1.33e-1)" "unprognostic (3.70e-3)" "unprognostic (2.35e-1)" "unprognostic (4.19e-2)" "potential prognostic favorable (1.50e-4)" "unprognostic (1.96e-1)" "unprognostic (1.41e-2)" "unprognostic (2.14e-1)" "unprognostic (6.17e-2)" "unprognostic (1.13e-1)" "unprognostic (1.54e-3)" "unprognostic (5.69e-2)" "unprognostic (7.24e-2)" "unprognostic (1.22e-2)" P2RY12 "HORK3, P2Y12, SP1999" ENSG00000169313 "Purinergic receptor P2Y12" Q9H244 3 151336843-151384753 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "Blood coagulation, Hemostasis" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 41.9" "Group enriched" "Detected in many" 10 "Microglia: 1602.7;Platelets: 537.9" "Cell type enriched" "Detected in all" 108 "central nervous system macrophage: 1814.1" "Cancer enriched" "Detected in some" 10 "Glioblastoma Multiforme (TCGA): 23.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 8.3" "Group enriched" "Detected in many" 11 "dendritic cells: 3.2;monocytes: 8.3" "Cancer enhanced" "Detected in single" "head and neck cancer: 3.0" "Adrenal gland - Macrophages, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013796, HPA014518" Enhanced NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 65: Non-specific - Unknown function" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" "HPA013796: , HPA014518: " "unprognostic (1.72e-2)" "unprognostic (8.45e-2)" "unprognostic (2.48e-2)" "unprognostic (5.79e-2)" "unprognostic (2.38e-3)" "unprognostic (2.10e-1)" "unprognostic (1.74e-2)" "potential prognostic favorable (1.84e-4)" "unprognostic (2.12e-1)" "unprognostic (1.29e-2)" "unprognostic (1.31e-1)" P2RY13 "FKSG77, GPR86, GPR94, P2Y13" ENSG00000181631 "Purinergic receptor P2Y13" Q9BPV8 3 151326312-151329549 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 23.7;lymphoid tissue: 34.7" "Cell type enhanced" "Detected in some" "cDC: 36.8;Kupffer cells: 261.4;Macrophages: 78.7;Microglia: 265.2;monocytes: 54.9;Neutrophil progenitors: 165.6;Neutrophils: 414.2" "Cell type enriched" "Detected in some" 31 "central nervous system macrophage: 300.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 583.2" "Group enriched" "Detected in many" 6 "granulocytes: 583.2;monocytes: 186.3" "Not detected" "Not detected" "Adrenal gland - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049047 Enhanced NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 1 "HPA049047: " "unprognostic (5.19e-2)" "unprognostic (1.46e-2)" "unprognostic (5.54e-3)" "unprognostic (7.03e-2)" "unprognostic (5.30e-2)" "unprognostic (1.14e-1)" "unprognostic (4.75e-2)" "unprognostic (6.53e-2)" "unprognostic (8.74e-3)" "potential prognostic favorable (3.38e-5)" "unprognostic (9.90e-2)" "unprognostic (1.41e-2)" "unprognostic (4.43e-3)" "potential prognostic favorable (1.10e-4)" "unprognostic (6.76e-2)" "unprognostic (1.16e-1)" "unprognostic (6.87e-2)" "unprognostic (9.84e-2)" "unprognostic (1.63e-1)" "unprognostic (1.56e-2)" "unprognostic (1.65e-1)" "unprognostic (1.51e-1)" "unprognostic (2.26e-2)" "unprognostic (2.48e-1)" "unprognostic (3.43e-1)" "unprognostic (2.20e-1)" "unprognostic (5.98e-3)" P2RY14 "GPR105, KIAA0001" ENSG00000174944 "Purinergic receptor P2Y14" Q15391 3 151212117-151278542 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 29.8" "Cell type enhanced" "Detected in many" "cDC: 260.7;Decidual stromal cells: 234.0;Hematopoietic stem cells: 316.9;Macrophages: 140.2;Mast cells: 178.3;Megakaryocyte progenitors: 234.0;Megakaryocyte-Erythroid progenitors: 166.1;Müller glia: 132.0;pDCs: 336.8;Pericytes: 142.0;Retinal horizontal cells: 106.2" "Cell type enriched" "Detected in all" 4 "pericyte: 985.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "choroid plexus: 57.6" "Group enriched" "Detected in many" 9 "eosinophil: 230.9;plasmacytoid DC: 98.2" "Group enriched" "Detected in many" 9 "dendritic cells: 98.2;granulocytes: 230.9" "Cancer enhanced" "Detected in some" "Leukemia: 1.6;Rhabdoid: 2.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022646 Uncertain NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 23: Choroid plexus - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" "CAB022646: " "unprognostic (1.52e-1)" "unprognostic (8.45e-2)" "unprognostic (6.08e-3)" "unprognostic (1.61e-1)" "unprognostic (7.93e-2)" "unprognostic (1.48e-1)" "unprognostic (7.93e-2)" "unprognostic (1.08e-3)" "unprognostic (6.71e-3)" "potential prognostic favorable (3.07e-4)" "unprognostic (2.70e-1)" "unprognostic (2.48e-2)" "unprognostic (2.39e-2)" "unprognostic (3.57e-2)" "unprognostic (3.54e-1)" "unprognostic (2.12e-1)" "unprognostic (9.31e-2)" "unprognostic (1.75e-2)" "unprognostic (2.45e-2)" "unprognostic (1.10e-1)" P2RY2 P2U ENSG00000175591 "Purinergic receptor P2Y2" P41231 11 73218281-73242427 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 27.5;skeletal muscle: 46.6;tongue: 29.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 21.2;Esophageal apical cells: 114.2;Esophageal basal cells: 29.9;Esophageal suprabasal cells: 68.5;Monocyte progenitors: 21.7;Myonuclei: 25.1;Neutrophil progenitors: 19.8" "Cell type enhanced" "Detected in some" "astrocyte: 1.3;pericyte: 3.3;vascular associated smooth muscle cell: 1.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 57.7" "Group enriched" "Detected in many" 12 "granulocytes: 57.7;monocytes: 20.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB022642 Uncertain Uncertain Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 85: Squamous epithelial cells - Keratinization" 66 Cytosol "CAB022642: " "unprognostic (3.59e-1)" "unprognostic (3.29e-2)" "unprognostic (1.46e-1)" "unprognostic (1.22e-1)" "unprognostic (8.69e-2)" "unprognostic (5.56e-2)" "unprognostic (4.14e-2)" "unprognostic (1.45e-2)" "unprognostic (3.15e-3)" "unprognostic (1.12e-2)" "unprognostic (1.08e-2)" "unprognostic (5.41e-2)" "unprognostic (4.64e-2)" "unprognostic (5.50e-3)" "unprognostic (2.07e-2)" "unprognostic (4.66e-2)" "validated prognostic unfavorable (8.61e-6)" "validated prognostic unfavorable (4.92e-4)" "unprognostic (8.34e-2)" "potential prognostic unfavorable (7.26e-4)" "unprognostic (3.37e-1)" "unprognostic (1.30e-1)" "unprognostic (2.06e-1)" "unprognostic (5.56e-3)" P2RY4 "NRU, P2P, P2Y4, UNR" ENSG00000186912 "Pyrimidinergic receptor P2Y4" P51582 X 70258166-70260204 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "intestine: 2.1" "Cell type enriched" "Detected in single" 6 "Goblet cells: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB022644 Uncertain NA NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 6: Non-specific - Immune response" "Cluster 56: Non-specific - Sensory perception" "Cluster 70: Intestinal goblet cells - Mucin production" 1 "CAB022644: " "unprognostic (2.16e-1)" P2RY6 P2Y6 ENSG00000171631 "Pyrimidinergic receptor P2Y6" Q15077 11 73264498-73305103 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 32.1" "Cell type enhanced" "Detected in many" "cDC: 78.3;Cytotrophoblasts: 230.6;Kupffer cells: 49.2;Macrophages: 50.0;Microglia: 75.7;Migrating cytotrophoblasts: 135.9;pDCs: 237.1;Syncytiotrophoblasts: 478.3" "Cell type enriched" "Detected in some" 17 "central nervous system macrophage: 79.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 12 "myeloid DC: 27.2;plasmacytoid DC: 87.6" "Lineage enriched" "Detected in many" 19 "dendritic cells: 87.6" "Low cancer specificity" "Detected in many" "Adrenal gland - Macrophages, Kidney - Macrophages, Stomach - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA074751 Enhanced NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 51: Neurons - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 19 "HPA074751: " "unprognostic (1.72e-1)" "unprognostic (3.78e-2)" "unprognostic (1.63e-1)" "unprognostic (3.32e-2)" "unprognostic (9.22e-2)" "unprognostic (1.73e-1)" "unprognostic (4.47e-3)" "unprognostic (1.26e-1)" "unprognostic (1.40e-2)" "unprognostic (1.47e-1)" "unprognostic (1.78e-3)" "unprognostic (1.61e-2)" "unprognostic (3.33e-2)" "unprognostic (2.77e-3)" "unprognostic (7.39e-2)" "validated prognostic unfavorable (4.47e-5)" "validated prognostic unfavorable (7.51e-4)" "unprognostic (2.50e-2)" "unprognostic (2.75e-2)" "unprognostic (7.20e-2)" "unprognostic (1.21e-1)" "unprognostic (1.70e-2)" "unprognostic (3.25e-3)" "unprognostic (1.10e-1)" "unprognostic (1.36e-1)" "unprognostic (1.18e-1)" "unprognostic (9.51e-3)" "unprognostic (3.71e-3)" "unprognostic (2.33e-2)" "unprognostic (1.18e-1)" "unprognostic (3.83e-1)" P2RY8 P2Y8 ENSG00000182162 "P2Y receptor family member 8" Q86VZ1 X 1462581-1537185 "Cancer-related genes, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 29.4;lymphoid tissue: 37.4" "Cell type enhanced" "Detected in many" "B-cells: 307.6;Hematopoietic stem cells: 326.1;Innate lymphoid cells: 261.9;Monocyte progenitors: 213.1;monocytes: 138.3;Neutrophil progenitors: 255.9;Neutrophils: 322.2;NK-cells: 211.3;Plasma cells: 209.7;T-cells: 221.6;Thymocytes: 218.5" "Cell type enriched" "Detected in single" 7 "leukocyte: 2.3" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 12.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 20 "Leukemia: 63.3;lymphoma: 94.3;Myeloma: 49.0" "Heart muscle - Endothelial cells, Lung - T-cells, Stomach - Plasma cells" "Low region specificity" "Detected in many" HPA003631 Enhanced NA NA "Cluster 24: Non-specific - Transcription" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 105 "HPA003631: " "unprognostic (1.13e-1)" "unprognostic (5.77e-2)" "unprognostic (2.39e-2)" "potential prognostic favorable (8.16e-4)" "unprognostic (1.73e-1)" "unprognostic (2.02e-1)" "unprognostic (1.69e-1)" "potential prognostic favorable (1.88e-4)" "potential prognostic favorable (2.79e-5)" "validated prognostic favorable (3.00e-10)" "validated prognostic favorable (9.81e-5)" "unprognostic (1.81e-2)" "potential prognostic favorable (1.84e-4)" "potential prognostic favorable (1.22e-4)" "unprognostic (1.13e-2)" "unprognostic (1.97e-2)" "unprognostic (2.27e-1)" "unprognostic (5.82e-3)" "unprognostic (1.40e-3)" "unprognostic (1.57e-1)" "unprognostic (2.62e-2)" "unprognostic (6.45e-2)" "unprognostic (1.53e-3)" "unprognostic (1.35e-1)" "unprognostic (2.87e-1)" "unprognostic (2.21e-2)" "unprognostic (1.93e-1)" P3H1 "GROS1, LEPRE1, LEPRECAN, MGC117314" ENSG00000117385 "Prolyl 3-hydroxylase 1" Q32P28 1 42746335-42767084 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Dwarfism, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 63.0;Extravillous trophoblasts: 91.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012113, HPA016980" Approved Approved Nucleoli,Vesicles "Intracellular and membrane" Enzyme NA NA 16000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 8: Immune cells - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 108: Fibroblasts - ECM organization" 10 Vesicles Nucleoli "HPA012113: , HPA016980: " "unprognostic (2.33e-1)" "unprognostic (2.08e-1)" "unprognostic (8.68e-2)" "unprognostic (1.06e-1)" "unprognostic (3.51e-2)" "unprognostic (7.53e-2)" "unprognostic (1.40e-1)" "unprognostic (2.30e-2)" "unprognostic (2.35e-2)" "potential prognostic unfavorable (4.25e-4)" "unprognostic (7.43e-3)" "unprognostic (2.02e-2)" "potential prognostic unfavorable (1.87e-6)" "unprognostic (2.84e-3)" "potential prognostic unfavorable (3.83e-4)" "unprognostic (8.33e-2)" "unprognostic (1.85e-1)" "unprognostic (2.17e-1)" "unprognostic (1.13e-1)" "unprognostic (4.01e-1)" "unprognostic (1.82e-2)" "unprognostic (8.49e-2)" "unprognostic (3.38e-2)" "unprognostic (9.22e-2)" "unprognostic (7.53e-3)" "unprognostic (5.32e-2)" "unprognostic (8.07e-2)" "unprognostic (3.07e-3)" "unprognostic (7.93e-2)" P3H2 "FLJ10718, LEPREL1, MLAT4" ENSG00000090530 "Prolyl 3-hydroxylase 2" Q8IVL5 3 189956728-190122437 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 848.3;Alveolar cells type 2: 439.1;Basal keratinocytes: 349.4;Foveolar cells: 401.2;Loop of henle epithelial cells: 583.4;Ocular epithelial cells: 375.8;Pituicytes/FSCs: 522.8;Podocytes: 688.9;Prostatic glandular cells: 368.5;Proximal tubule cells: 1160.5;Renal collecting duct intercalated cells: 355.3" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 389.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 22 "plasmacytoid DC: 28.9" "Lineage enriched" "Detected in single" 112 "dendritic cells: 28.9" "Cancer enhanced" "Detected in all" "Kidney cancer: 132.1" "Breast - Breast myoepithelial cells, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Skeletal muscle - Fibroblasts, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA007890, HPA013355, HPA013611" Approved Supported "Nucleoplasm,Golgi apparatus,Vesicles,Cytosol" "Intracellular and membrane" Enzyme NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 22: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 88: Proximal tubular cells - Transmembrane transport" "Golgi apparatus" "Nucleoplasm, Vesicles, Cytosol" "HPA007890: , HPA013355: , HPA013611: " "unprognostic (3.16e-1)" "unprognostic (1.35e-2)" "unprognostic (1.21e-1)" "unprognostic (4.55e-1)" "unprognostic (1.06e-2)" "unprognostic (7.85e-3)" "unprognostic (3.08e-3)" "unprognostic (1.06e-1)" "unprognostic (3.70e-3)" "unprognostic (9.14e-3)" "unprognostic (1.81e-1)" "unprognostic (2.46e-1)" "unprognostic (5.35e-2)" "unprognostic (1.06e-1)" "unprognostic (8.81e-2)" "unprognostic (1.39e-1)" "unprognostic (1.53e-1)" "unprognostic (9.64e-2)" "unprognostic (2.73e-1)" "potential prognostic unfavorable (4.33e-4)" "unprognostic (1.20e-1)" "unprognostic (2.68e-1)" "unprognostic (1.15e-1)" "unprognostic (1.36e-2)" "unprognostic (2.29e-1)" "unprognostic (8.21e-3)" "unprognostic (1.93e-1)" "unprognostic (1.30e-1)" "unprognostic (1.24e-1)" P3H3 "GRCB, HSU47926, LEPREL2" ENSG00000110811 "Prolyl 3-hydroxylase 3" Q8IVL6 12 6828407-6839847 "Enzymes, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 80.7;Corticotrophs: 45.9;Lactotrophs: 37.9;Leydig cells: 71.1;Peritubular myoid cells: 53.8;Retinal bipolar cells: 54.1;Retinal horizontal cells: 96.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043695 Approved Approved "Nucleoli,Plasma membrane,Cytosol" "Intracellular and membrane" Enzyme NA NA "Cluster 64: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 94: Gonadal somatic cells - Mixed function" 27 "Plasma membrane, Cytosol" Nucleoli "HPA043695: " "unprognostic (1.06e-1)" "unprognostic (1.25e-1)" "unprognostic (9.98e-2)" "unprognostic (8.32e-2)" "unprognostic (2.66e-2)" "unprognostic (2.87e-2)" "unprognostic (2.99e-3)" "unprognostic (1.46e-1)" "unprognostic (5.25e-3)" "unprognostic (3.52e-1)" "unprognostic (2.57e-2)" "unprognostic (3.45e-1)" "unprognostic (3.66e-1)" "unprognostic (1.76e-1)" "unprognostic (4.22e-2)" "unprognostic (1.85e-2)" "unprognostic (2.79e-1)" "potential prognostic favorable (6.32e-5)" "unprognostic (1.77e-1)" "unprognostic (3.05e-1)" "unprognostic (3.13e-2)" "unprognostic (9.78e-3)" "unprognostic (2.87e-2)" "unprognostic (4.68e-3)" "unprognostic (8.57e-2)" "unprognostic (1.07e-2)" "unprognostic (1.98e-1)" P3H4 "LEPREL4, NO55, SC65" ENSG00000141696 "Prolyl 3-hydroxylase family member 4 (inactive)" Q92791 17 41801947-41812604 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Granulosa cells: 44.6;Hepatic stellate cells: 58.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 3.9;MAIT T-cell: 5.0;memory CD4 T-cell: 2.5;memory CD8 T-cell: 2.6;naive CD4 T-cell: 2.9;naive CD8 T-cell: 3.9;NK-cell: 8.5" "Group enriched" "Detected in many" 11 "NK-cells: 8.5;T-cells: 5.0" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022520 Approved "Endoplasmic reticulum,Vesicles" "Intracellular and membrane" "No annotated function" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 70: Non-specific - Protein processing" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 26 "Endoplasmic reticulum, Vesicles" "HPA022520: " "unprognostic (7.49e-2)" "unprognostic (3.34e-3)" "unprognostic (1.60e-3)" "unprognostic (3.32e-1)" "unprognostic (8.34e-2)" "unprognostic (6.43e-3)" "unprognostic (4.91e-2)" "unprognostic (3.07e-2)" "unprognostic (1.40e-1)" "validated prognostic unfavorable (3.79e-4)" "validated prognostic unfavorable (6.94e-5)" "unprognostic (4.30e-2)" "unprognostic (9.92e-3)" "validated prognostic unfavorable (4.75e-4)" "validated prognostic unfavorable (2.09e-4)" "unprognostic (1.98e-2)" "unprognostic (1.34e-1)" "unprognostic (7.09e-3)" "unprognostic (2.51e-2)" "unprognostic (2.93e-1)" "unprognostic (2.44e-2)" "unprognostic (1.74e-1)" "unprognostic (1.98e-1)" "unprognostic (8.81e-2)" "unprognostic (2.42e-3)" "unprognostic (1.80e-1)" "unprognostic (2.35e-1)" "unprognostic (4.61e-2)" "unprognostic (1.55e-1)" P3R3URF ENSG00000250719 "PIK3R3 upstream open reading frame" A0A087WWA1 1 46175486-46176488 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 931 "testis: 133.6" "Cell type enriched" "Detected in some" 9 "Late spermatids: 6211.2" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebellum: 3.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 2.4" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 2: Neurons - Nucleosome" "Cluster 7: Liver cancer - Metabolism" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" P3R3URF-PIK3R3 ENSG00000278139 "P3R3URF-PIK3R3 readthrough" 1 46043661-46176488 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 26 "testis: 20.1" "Group enriched" "Detected in some" 10 "Early spermatids: 324.1;Endometrial luminal cells: 177.3;Late spermatids: 366.9" "Cell type enhanced" "Detected in many" "Bergmann glia: 13.4" "Not detected" "Not detected" "Region enriched" "Detected in some" 6 "cerebellum: 6.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA005751 Uncertain Approved "Nucleoplasm,Cytosol,Connecting piece,Mid piece,Principal piece,End piece" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 35: Non-specific - DNA binding" "Cluster 61: BICR 18 - Protein kinases" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" "Nucleoplasm, Cytosol" "Connecting piece, Mid piece, Principal piece, End piece" "HPA005751: " P4HA1 "C-P4Halpha(I), P4HA" ENSG00000122884 "Prolyl 4-hydroxylase subunit alpha 1" P13674 10 73007217-73096974 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Myonuclei: 565.9;Thymic myoid cells: 439.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007599, HPA026593" Enhanced Supported "Endoplasmic reticulum,Vesicles,Mitochondria" "Intracellular and membrane" Enzyme Yes No 85000 "Cluster 40: Monocytes - Innate immune response" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 55: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 75: Non-specific - Chaperones and protein folding" 51 "Endoplasmic reticulum" "Vesicles, Mitochondria" "HPA007599: , HPA026593: " "unprognostic (1.20e-1)" "potential prognostic unfavorable (3.34e-4)" "unprognostic (1.77e-1)" "potential prognostic unfavorable (1.27e-4)" "unprognostic (3.02e-2)" "unprognostic (7.95e-2)" "potential prognostic unfavorable (5.25e-4)" "unprognostic (3.90e-1)" "potential prognostic unfavorable (4.15e-4)" "potential prognostic unfavorable (1.45e-7)" "unprognostic (3.74e-3)" "unprognostic (1.21e-1)" "potential prognostic unfavorable (4.02e-6)" "unprognostic (3.96e-1)" "unprognostic (1.24e-1)" "unprognostic (2.79e-3)" "unprognostic (1.75e-2)" "unprognostic (5.90e-2)" "unprognostic (5.61e-2)" "unprognostic (3.23e-2)" "unprognostic (5.57e-3)" "potential prognostic unfavorable (7.01e-4)" "unprognostic (1.01e-3)" "unprognostic (3.10e-2)" "unprognostic (3.38e-1)" "unprognostic (1.70e-1)" "unprognostic (1.67e-1)" "unprognostic (1.33e-1)" "unprognostic (1.77e-1)" "unprognostic (4.35e-3)" "unprognostic (2.94e-2)" P4HA2 "C-P4Halpha(II), lncRNA-PE" ENSG00000072682 "Prolyl 4-hydroxylase subunit alpha 2" O15460 5 132190147-132295315 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 190.2;Decidual stromal cells: 137.0;Epicardial cells: 211.5;Proximal tubule cells: 198.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Kidney - Proximal tubular cells, Minor Salivary Gland - Minor salivary glandular cells, Spleen - Fibroblasts_1, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA016997, HPA027824, CAB062557" Enhanced Enhanced "Endoplasmic reticulum,Vesicles" "Intracellular and membrane" Enzyme No No 15000 "Cluster 35: Neutrophils - Protein binding" "Cluster 60: Stomach - Digestion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 108: Fibroblasts - ECM organization" 18 "Endoplasmic reticulum, Vesicles" "CAB062557: , HPA016997: , HPA027824: " "unprognostic (2.74e-1)" "potential prognostic unfavorable (5.63e-4)" "unprognostic (1.08e-1)" "potential prognostic unfavorable (1.17e-4)" "unprognostic (5.30e-2)" "unprognostic (4.80e-2)" "unprognostic (2.14e-3)" "unprognostic (3.33e-2)" "unprognostic (3.40e-3)" "potential prognostic unfavorable (2.05e-4)" "potential prognostic favorable (4.56e-4)" "unprognostic (3.19e-1)" "potential prognostic unfavorable (5.23e-5)" "potential prognostic unfavorable (9.38e-4)" "unprognostic (1.87e-1)" "unprognostic (9.81e-3)" "potential prognostic unfavorable (7.16e-5)" "unprognostic (1.03e-2)" "unprognostic (3.14e-2)" "unprognostic (1.24e-1)" "unprognostic (2.03e-3)" "unprognostic (5.57e-2)" "unprognostic (2.03e-2)" "unprognostic (2.42e-1)" "unprognostic (2.25e-1)" "unprognostic (9.08e-2)" "unprognostic (5.29e-2)" "unprognostic (9.59e-3)" "unprognostic (2.64e-1)" "unprognostic (1.69e-1)" "unprognostic (5.67e-2)" P4HA3 C-P4Halpha(III) ENSG00000149380 "Prolyl 4-hydroxylase subunit alpha 3" Q7Z4N8 11 74235801-74311640 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 8.3;smooth muscle: 9.7" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 67.5;Early primary spermatocytes: 145.9;Early spermatids: 66.5;Epicardial cells: 63.7;Myonuclei: 71.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 7.2" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Lung - Fibroblasts_2, Prostate - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA007897 Approved Approved Cytosol "Intracellular and membrane" Enzyme NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 41 Cytosol "HPA007897: " "unprognostic (1.60e-1)" "unprognostic (9.16e-2)" "unprognostic (3.03e-1)" "unprognostic (3.18e-2)" "unprognostic (1.08e-3)" "unprognostic (3.52e-2)" "unprognostic (1.74e-1)" "unprognostic (3.32e-2)" "unprognostic (2.69e-1)" "potential prognostic unfavorable (7.68e-4)" "unprognostic (3.50e-2)" "unprognostic (1.83e-1)" "unprognostic (1.12e-1)" "unprognostic (3.96e-3)" "unprognostic (1.79e-2)" "unprognostic (9.87e-3)" "unprognostic (1.23e-2)" "unprognostic (2.48e-2)" "unprognostic (3.41e-2)" "unprognostic (1.18e-1)" "unprognostic (6.90e-2)" "unprognostic (2.95e-2)" "unprognostic (6.86e-2)" "unprognostic (1.25e-2)" "unprognostic (4.05e-3)" "unprognostic (2.63e-2)" "unprognostic (8.17e-3)" P4HB "DSI, ERBA2L, GIT, P4Hbeta, PDI, PDIA1, PO4DB, PO4HB, PROHB" ENSG00000185624 "Prolyl 4-hydroxylase subunit beta" P07237 17 81843159-81860856 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Chaperone, Isomerase" "Craniosynostosis, Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 2108.3" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 2747.6;Esophageal suprabasal cells: 1072.3;Extravillous trophoblasts: 1918.6;Migrating cytotrophoblasts: 1116.0;Pancreatic acinar cells: 2020.9;Syncytiotrophoblasts: 1193.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012463, HPA018884" Enhanced Supported "Endoplasmic reticulum" "Intracellular and membrane" Enzyme No No 72000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 8: Pancreas - Proteolysis" "Cluster 12: Non-specific - Vasculature" "Cluster 63: Non-specific - Protein processing" "Cluster 8: Non-specific - Secretory pathway" 103 "Endoplasmic reticulum" "CAB012463: , HPA018884: " "unprognostic (8.56e-2)" "unprognostic (2.58e-1)" "unprognostic (8.87e-2)" "potential prognostic unfavorable (3.87e-4)" "unprognostic (2.67e-2)" "unprognostic (1.13e-1)" "unprognostic (9.41e-3)" "unprognostic (3.41e-3)" "unprognostic (6.88e-2)" "unprognostic (4.46e-2)" "potential prognostic favorable (5.44e-4)" "potential prognostic unfavorable (5.26e-6)" "unprognostic (6.34e-3)" "unprognostic (2.26e-1)" "unprognostic (1.91e-3)" "unprognostic (4.06e-2)" "unprognostic (1.85e-3)" "unprognostic (3.73e-2)" "unprognostic (1.31e-1)" "unprognostic (6.36e-2)" "unprognostic (1.08e-2)" "unprognostic (1.40e-2)" "unprognostic (2.56e-1)" "unprognostic (2.74e-1)" "unprognostic (2.27e-1)" "unprognostic (1.29e-1)" "unprognostic (1.10e-1)" "unprognostic (6.12e-2)" "unprognostic (1.94e-1)" "unprognostic (1.58e-3)" "unprognostic (5.43e-2)" P4HTM "EGLN4, FLJ20262, HIFPH4, P4H-TM, PH-4, PH4, PHD4" ENSG00000178467 "Prolyl 4-hydroxylase, transmembrane" Q9NXG6 3 48989889-49007153 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Dioxygenase, Oxidoreductase" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 161.1" "Cell type enhanced" "Detected in many" "Fallopian tube ciliated cells: 277.4;Late spermatids: 230.1;Pancreatic islet cells: 150.2;Respiratory ciliated cells: 246.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Lung - Respiratory ciliated cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007199 Supported Uncertain Vesicles,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 1 "Vesicles, Cytosol" "HPA007199: " "unprognostic (2.27e-2)" "unprognostic (2.11e-1)" "unprognostic (3.61e-1)" "unprognostic (1.31e-1)" "unprognostic (7.08e-3)" "unprognostic (7.23e-2)" "unprognostic (1.06e-2)" "unprognostic (1.22e-1)" "unprognostic (2.27e-1)" "unprognostic (4.94e-3)" "potential prognostic favorable (8.98e-5)" "unprognostic (1.83e-2)" "potential prognostic favorable (2.86e-7)" "unprognostic (3.11e-2)" "unprognostic (5.12e-3)" "unprognostic (5.78e-3)" "unprognostic (2.72e-1)" "unprognostic (3.21e-2)" "unprognostic (1.49e-1)" "unprognostic (5.13e-3)" "unprognostic (2.96e-1)" "unprognostic (2.03e-2)" "unprognostic (2.58e-1)" "unprognostic (1.06e-1)" "unprognostic (1.81e-1)" "unprognostic (1.48e-2)" "unprognostic (4.42e-2)" "unprognostic (7.58e-3)" "unprognostic (2.20e-1)" "unprognostic (5.15e-2)" "unprognostic (4.61e-2)" PA2G4 EBP1 ENSG00000170515 "Proliferation-associated 2G4" Q9UQ80 12 56104537-56113910 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "rRNA processing, Transcription, Transcription regulation, Translation regulation" "Repressor, Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 404.8;Esophageal basal cells: 473.1;Late primary spermatocytes: 603.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011711, CAB012428, HPA016484" Supported Supported Cytosol NA NA 4900000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 79 Cytosol "CAB011711: , CAB012428: , HPA016484: " "potential prognostic unfavorable (5.70e-5)" "unprognostic (6.53e-2)" "unprognostic (1.45e-2)" "unprognostic (6.45e-2)" "unprognostic (7.41e-2)" "unprognostic (1.35e-1)" "unprognostic (1.13e-1)" "unprognostic (1.15e-3)" "unprognostic (6.50e-3)" "unprognostic (1.03e-2)" "unprognostic (5.73e-3)" "unprognostic (2.48e-1)" "unprognostic (2.75e-3)" "validated prognostic unfavorable (2.74e-6)" "validated prognostic unfavorable (1.50e-6)" "validated prognostic unfavorable (7.91e-5)" "validated prognostic unfavorable (3.04e-4)" "unprognostic (1.28e-1)" "unprognostic (4.07e-2)" "unprognostic (6.72e-2)" "unprognostic (3.16e-1)" "unprognostic (6.71e-3)" "unprognostic (5.42e-2)" "unprognostic (9.16e-3)" "unprognostic (1.60e-1)" "unprognostic (1.49e-1)" "unprognostic (1.63e-1)" "unprognostic (1.66e-1)" "unprognostic (1.56e-1)" "unprognostic (1.82e-1)" "unprognostic (7.36e-3)" PAAF1 "FLJ11848, Rpn14, WDR71" ENSG00000175575 "Proteasomal ATPase associated factor 1" Q9BRP4 11 73876699-73931114 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 110.8" "Cell type enhanced" "Detected in many" "Myonuclei: 126.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "HPA039952, HPA040020" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 24: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 68 Nucleoplasm Cytosol "HPA039952: , HPA040020: " "unprognostic (1.89e-1)" "unprognostic (3.15e-2)" "unprognostic (4.24e-2)" "unprognostic (5.12e-2)" "unprognostic (9.89e-2)" "unprognostic (3.20e-2)" "unprognostic (2.58e-1)" "potential prognostic favorable (1.94e-4)" "unprognostic (6.34e-2)" "unprognostic (7.61e-3)" "potential prognostic favorable (1.97e-6)" "unprognostic (1.26e-3)" "unprognostic (4.38e-2)" "unprognostic (9.45e-3)" "unprognostic (9.76e-3)" "unprognostic (2.04e-1)" "unprognostic (3.36e-2)" "unprognostic (2.86e-1)" "unprognostic (9.39e-3)" "unprognostic (1.71e-3)" "unprognostic (1.70e-1)" "unprognostic (3.59e-2)" "unprognostic (2.80e-1)" "unprognostic (3.05e-1)" "potential prognostic favorable (6.40e-5)" "unprognostic (1.71e-1)" "unprognostic (1.39e-1)" "unprognostic (1.04e-1)" "unprognostic (1.58e-1)" "unprognostic (3.74e-1)" "unprognostic (7.58e-2)" PABIR1 "C9orf42, FAM122A, MGC17347" ENSG00000187866 "PP2A Aalpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1" Q96E09 9 68780065-68785566 "Predicted intracellular proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056646 Approved Supported "Nucleoplasm,Nuclear bodies" No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 28: Liver & Adrenal gland - Secretion" "Cluster 5: Non-specific - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 21 "Nucleoplasm, Nuclear bodies" "HPA056646: " "unprognostic (1.18e-2)" "unprognostic (5.49e-2)" "unprognostic (3.24e-1)" "unprognostic (5.81e-3)" "unprognostic (2.65e-1)" "unprognostic (1.52e-1)" "unprognostic (2.78e-1)" "unprognostic (3.06e-1)" "unprognostic (1.02e-1)" "unprognostic (1.88e-1)" "validated prognostic favorable (5.00e-8)" "validated prognostic favorable (6.12e-5)" "unprognostic (6.04e-2)" "unprognostic (5.02e-1)" "unprognostic (1.63e-1)" "unprognostic (2.17e-2)" "unprognostic (4.15e-1)" "unprognostic (7.47e-2)" "unprognostic (3.22e-2)" "unprognostic (1.77e-2)" "unprognostic (1.37e-1)" "unprognostic (3.48e-2)" "unprognostic (4.89e-2)" "unprognostic (8.13e-2)" "unprognostic (3.56e-1)" "unprognostic (2.60e-1)" "unprognostic (2.19e-2)" "unprognostic (4.23e-3)" "unprognostic (5.17e-2)" "unprognostic (3.12e-1)" "unprognostic (9.18e-3)" PABIR2 "DKFZp686L20116, FAM122B, RP11-308B5.5" ENSG00000156504 "PABIR family member 2" Q7Z309 X 134769566-134797232 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Sertoli cells: 134.4;Tuft cells: 69.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Pancreas - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000266 Enhanced Approved Nucleoplasm NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 65: Brain - Transcription" "Cluster 7: Non-specific - Ribosome" "Cluster 36: Non-specific - mRNA processing" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 10 Nucleoplasm "HPA000266: " "unprognostic (1.30e-1)" "potential prognostic unfavorable (4.25e-4)" "unprognostic (2.95e-1)" "unprognostic (5.77e-2)" "unprognostic (1.02e-2)" "unprognostic (3.68e-1)" "unprognostic (3.03e-1)" "unprognostic (1.06e-1)" "unprognostic (1.34e-1)" "unprognostic (2.94e-3)" "unprognostic (9.67e-2)" "unprognostic (3.02e-1)" "unprognostic (2.65e-2)" "unprognostic (3.94e-3)" "unprognostic (3.83e-3)" "unprognostic (1.94e-1)" "unprognostic (4.30e-3)" "unprognostic (1.24e-1)" "unprognostic (2.31e-1)" "unprognostic (6.09e-2)" "unprognostic (1.50e-1)" "unprognostic (1.45e-1)" "potential prognostic unfavorable (3.70e-4)" "unprognostic (2.94e-2)" "unprognostic (1.40e-2)" "unprognostic (1.33e-2)" "unprognostic (1.22e-1)" "unprognostic (1.15e-1)" "unprognostic (4.42e-2)" "unprognostic (8.34e-2)" "unprognostic (2.13e-2)" PABIR3 "FAM122C, RP3-473B4.1" ENSG00000156500 "PABIR family member 3" Q6P4D5 X 134796395-134854835 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 97.5;Ependymal cells: 108.3;Granulosa cells: 111.9;Sertoli cells: 151.8;Tuft cells: 80.7" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 92.5;ependymal cell: 105.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts, Testis - Sertoli cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA059961 Approved Uncertain Nucleoplasm NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 4 Nucleoplasm "HPA059961: " "unprognostic (6.83e-2)" "unprognostic (2.85e-2)" "unprognostic (4.77e-2)" "unprognostic (8.63e-2)" "unprognostic (2.87e-3)" "unprognostic (6.59e-2)" "unprognostic (1.44e-1)" "unprognostic (5.56e-2)" "unprognostic (2.03e-1)" "potential prognostic unfavorable (6.41e-4)" "unprognostic (1.24e-2)" "unprognostic (8.64e-2)" "unprognostic (1.68e-1)" "unprognostic (1.88e-2)" "unprognostic (1.64e-2)" "unprognostic (7.56e-2)" "unprognostic (1.01e-1)" "unprognostic (2.88e-1)" "unprognostic (7.99e-2)" "unprognostic (7.32e-2)" "unprognostic (1.78e-1)" "unprognostic (7.47e-3)" "unprognostic (1.19e-1)" "unprognostic (1.14e-3)" "unprognostic (2.64e-1)" "unprognostic (1.61e-2)" "unprognostic (1.28e-1)" "unprognostic (6.17e-2)" "unprognostic (1.36e-1)" "unprognostic (7.90e-3)" PABPC1 "PAB1, PABP1, PABPC2, PABPL1" ENSG00000070756 "Poly(A) binding protein cytoplasmic 1" P11940 8 100685816-100722809 "Cancer-related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing, Nonsense-mediated mRNA decay" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 1212.8" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 8505.5;Late primary spermatocytes: 2561.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "CAB011536, HPA045423, HPA067156" Supported Supported Cytosol NA NA 2800000 "Cluster 13: Non-specific - Mitochondria" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 40: Non-specific - Unknown function" "Cluster 84: Apical squamous epithelium - Cornification" 189 Cytosol "CAB011536: , HPA045423: , HPA067156: " "unprognostic (1.07e-2)" "unprognostic (3.65e-2)" "unprognostic (1.28e-1)" "unprognostic (8.61e-3)" "unprognostic (2.02e-1)" "unprognostic (8.06e-3)" "unprognostic (5.98e-2)" "unprognostic (2.74e-1)" "unprognostic (1.69e-1)" "potential prognostic unfavorable (3.61e-4)" "unprognostic (1.11e-1)" "unprognostic (5.94e-2)" "potential prognostic unfavorable (5.36e-7)" "unprognostic (7.72e-3)" "potential prognostic unfavorable (6.33e-4)" "potential prognostic unfavorable (7.79e-4)" "unprognostic (1.27e-3)" "unprognostic (1.27e-1)" "unprognostic (7.73e-2)" "unprognostic (1.63e-3)" "unprognostic (4.07e-3)" "unprognostic (4.34e-3)" "unprognostic (9.05e-2)" "unprognostic (6.87e-2)" "unprognostic (7.89e-2)" "unprognostic (6.29e-2)" "unprognostic (2.95e-1)" "unprognostic (2.33e-1)" "unprognostic (1.59e-1)" "unprognostic (1.48e-1)" "unprognostic (2.54e-1)" PABPC1L "C20orf119, dJ1069P2.3, ePAB, PABPC1L1" ENSG00000101104 "Poly(A) binding protein cytoplasmic 1 like" Q4VXU2 20 44910060-44959035 "Predicted intracellular proteins" "Differentiation, Oogenesis" RNA-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Neutrophils: 89.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA066650 Approved "Nuclear bodies,Cytosol" NA Yes "Cluster 70: Non-specific - Protein processing" "Cluster 17: Choroid plexus - Cilium" "Cluster 56: Non-specific - Sensory perception" "Cluster 24: Neutrophils - Innate immunity signal integration" 1 Cytosol "Nuclear bodies" "HPA066650: " "unprognostic (1.29e-1)" "unprognostic (4.89e-2)" "unprognostic (2.56e-2)" "unprognostic (2.93e-2)" "unprognostic (8.53e-3)" "unprognostic (1.54e-1)" "unprognostic (1.42e-1)" "unprognostic (3.66e-2)" "unprognostic (7.48e-2)" "potential prognostic unfavorable (1.50e-9)" "unprognostic (1.40e-2)" "unprognostic (2.48e-1)" "unprognostic (8.05e-2)" "unprognostic (7.51e-2)" "unprognostic (5.24e-3)" "unprognostic (2.75e-1)" "unprognostic (3.08e-1)" "unprognostic (1.13e-1)" "unprognostic (5.53e-2)" "unprognostic (8.97e-2)" "unprognostic (6.11e-3)" "potential prognostic unfavorable (1.72e-4)" "potential prognostic unfavorable (9.16e-4)" "unprognostic (5.23e-3)" "potential prognostic favorable (2.58e-4)" "unprognostic (1.04e-2)" "unprognostic (3.69e-2)" "unprognostic (2.24e-1)" "unprognostic (3.27e-1)" "unprognostic (3.59e-2)" PABPC1L2A RBM32A ENSG00000186288 "Poly(A) binding protein cytoplasmic 1 like 2A" Q5JQF8 X 73077276-73079512 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 10.5" "Cell type enriched" "Detected in some" 4 "Late spermatids: 180.9" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in single" 17 "Prostate Adenocarcinoma (TCGA): 7.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Testis - Late spermatids" HPA041573 Approved NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 1: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 3 "HPA041573: " "unprognostic (1.95e-1)" PABPC1L2B RBM32B ENSG00000184388 "Poly(A) binding protein cytoplasmic 1 like 2B" Q5JQF8 X 73002939-73006106 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 7.9;prostate: 2.0;salivary gland: 1.7" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 5.2;Brain inhibitory neurons: 5.3;Early primary spermatocytes: 1.9;Gonadotrophs: 1.5;Lactotrophs: 1.3;Oligodendrocyte progenitor cells: 3.6;Oligodendrocytes: 2.4;Other brain neurons: 8.4;Prostatic glandular cells: 5.3" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in single" 25 "Prostate Adenocarcinoma (TCGA): 7.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells" HPA041573 Approved NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 1: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 98: Neurons - Neurotransmission & signaling" "HPA041573: " "unprognostic (7.32e-2)" PABPC3 "PABP3, PABPL3, tPABP" ENSG00000151846 "Poly(A) binding protein cytoplasmic 3" Q9H361 13 25096136-25099254 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 142 "testis: 34.4" "Cell type enriched" "Detected in some" 6 "Late primary spermatocytes: 131.7" "Cell type enhanced" "Detected in some" "Bergmann glia: 3.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "HPA045423, HPA067156" Approved Approved Cytosol NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 61: BICR 18 - Protein kinases" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 9 Cytosol "HPA045423: , HPA067156: " "unprognostic (1.19e-1)" "unprognostic (5.12e-3)" PABPC4 "APP-1, iPABP" ENSG00000090621 "Poly(A) binding protein cytoplasmic 4" Q13310 1 39560709-39576790 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 338.9;skeletal muscle: 448.1" "Cell type enhanced" "Detected in many" "Kupffer cells: 565.7;Pancreatic acinar cells: 444.4" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 80.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027301, HPA056496" Supported Enhanced Cytosol NA NA 540000 "Cluster 13: Non-specific - Mitochondria" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 12: Non-specific - Vasculature" "Cluster 37: Non-specific - mRNA processing" "Cluster 67: Plasma cells - Plasma cell differentiation" 101 Cytosol "HPA027301: , HPA056496: " "unprognostic (4.56e-2)" "unprognostic (2.18e-1)" "unprognostic (1.77e-1)" "potential prognostic unfavorable (9.65e-4)" "unprognostic (4.52e-2)" "unprognostic (4.72e-2)" "unprognostic (7.14e-2)" "unprognostic (2.77e-1)" "potential prognostic unfavorable (7.35e-4)" "unprognostic (6.78e-3)" "unprognostic (5.02e-3)" "unprognostic (8.32e-2)" "potential prognostic unfavorable (4.08e-7)" "validated prognostic unfavorable (4.56e-6)" "validated prognostic unfavorable (3.16e-4)" "unprognostic (7.18e-2)" "unprognostic (3.35e-3)" "unprognostic (4.13e-2)" "unprognostic (4.44e-2)" "unprognostic (2.03e-1)" "unprognostic (1.65e-1)" "unprognostic (6.60e-3)" "unprognostic (8.54e-2)" "unprognostic (9.42e-2)" "unprognostic (3.09e-1)" "unprognostic (2.17e-2)" "unprognostic (1.76e-1)" "unprognostic (1.70e-1)" "unprognostic (2.63e-1)" "unprognostic (8.02e-2)" "unprognostic (2.58e-1)" PABPC4L ENSG00000254535 "Poly(A) binding protein cytoplasmic 4 like" P0CB38 4 134196333-134201789 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 9.6" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 4.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 7.6" "Adipose subcutaneous - Endothelial cells, Prostate - Fibroblasts, Skin - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 47: Endothelial cells - Vasculature" "Cluster 3: Rhabdoid - Membrane components" "Cluster 105: Non-specific - Mixed function" 1 "unprognostic (2.66e-1)" "unprognostic (2.24e-2)" "unprognostic (1.26e-2)" "potential prognostic favorable (1.33e-9)" "unprognostic (5.24e-3)" "unprognostic (1.46e-2)" "unprognostic (2.76e-1)" "unprognostic (3.03e-2)" "unprognostic (1.70e-1)" "unprognostic (5.00e-2)" "unprognostic (1.56e-1)" "unprognostic (4.75e-2)" "unprognostic (1.02e-1)" PABPC5 PABP5 ENSG00000174740 "Poly(A) binding protein cytoplasmic 5" Q96DU9 X 91434595-91438584 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 6.9;ovary: 8.8" "Cell type enhanced" "Detected in some" "Adrenal cortex cells: 24.0;Decidual stromal cells: 9.2;Fibroblasts: 7.4;Gonadotrophs: 8.0;Granulosa cells: 9.7;Leydig cells: 7.8;Melanocytes: 12.0;Myosatellite cells: 16.2;Oligodendrocyte progenitor cells: 8.5;Ovarian stromal cells: 8.7;Pericytes: 9.1;Peritubular myoid cells: 9.3;Retinal bipolar cells: 8.2;Somatotrophs: 8.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 1.7;skin cancer: 1.5" "Liver - Hepatic stellate cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA000164, HPA000165" Approved NA NA "Cluster 75: Ovary - Mixed function" "Cluster 27: Non-specific - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 110: Mural cells - ECM organization" 19 "HPA000164: , HPA000165: " "unprognostic (1.70e-1)" "unprognostic (1.19e-1)" "potential prognostic favorable (1.74e-5)" "unprognostic (4.26e-1)" "unprognostic (4.58e-3)" "unprognostic (9.25e-2)" PABPN1 "OPMD, PAB2, PABP2" ENSG00000100836 "Poly(A) binding protein nuclear 1" Q86U42 14 23321457-23326163 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing" RNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 192.7;Bergmann glia: 188.5;Brain excitatory neurons: 112.7;Brain inhibitory neurons: 117.1;Choroid plexus epithelial cells: 103.3;Distal convoluted tubule cells: 58.7;Ependymal cells: 162.0;Microglia: 108.5;Oligodendrocyte progenitor cells: 132.1;Oligodendrocytes: 137.6;Other brain neurons: 102.8;Podocytes: 184.0;Proximal tubule cells: 61.6;Renal collecting duct intercalated cells: 58.9;Renal connecting tubule cells: 59.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000637, HPA079093" Supported Supported "Nucleoplasm,Nuclear speckles" NA NA 12000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 102: Non-specific - Mixed function" 21 "Nucleoplasm, Nuclear speckles" "HPA000637: , HPA079093: " "unprognostic (1.20e-1)" "unprognostic (2.12e-3)" "unprognostic (1.08e-1)" "unprognostic (6.75e-2)" "unprognostic (9.05e-2)" "unprognostic (6.85e-2)" "unprognostic (8.71e-2)" "potential prognostic favorable (2.58e-4)" "unprognostic (9.20e-2)" "unprognostic (9.56e-2)" "potential prognostic unfavorable (5.46e-7)" "unprognostic (2.95e-1)" "unprognostic (1.80e-1)" "potential prognostic unfavorable (8.65e-4)" "unprognostic (2.80e-2)" "unprognostic (7.53e-2)" "unprognostic (2.54e-3)" "potential prognostic favorable (8.15e-4)" "unprognostic (1.61e-2)" "unprognostic (4.36e-2)" "unprognostic (1.74e-2)" "unprognostic (3.53e-2)" "unprognostic (2.20e-2)" "unprognostic (8.34e-2)" "unprognostic (2.90e-1)" "unprognostic (6.50e-2)" "unprognostic (1.19e-2)" "unprognostic (3.50e-1)" "unprognostic (5.45e-2)" "unprognostic (2.59e-1)" "unprognostic (9.88e-2)" PABPN1L ePABP2 ENSG00000205022 "PABPN1 like, cytoplasmic" A6NDY0 16 88863333-88866660 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 2.2;brain: 2.4" "Cell type enriched" "Detected in some" 35 "Oocytes: 59.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Myeloma: 1.2" "Adrenal gland - Adrenal cortex cells, Prostate - Prostate glandular cells" "Not detected" "Not detected" "Region enriched" "Detected in single" 8 "cerebellum: 2.1" HPA043415 Uncertain NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 15: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 41: Oocytes - Oogenesis" "HPA043415: " PACC1 "ASOR, C1orf75, FLJ10874, PAC, PAORAC, TMEM206" ENSG00000065600 "Proton activated chloride channel 1" Q9H813 1 212363928-212414901 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "brain: 70.2" "Cell type enhanced" "Detected in many" "Oligodendrocyte progenitor cells: 48.2;Oligodendrocytes: 98.8" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 93.6;oligodendrocyte: 119.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008540 Uncertain NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 45: Non-specific - Nuclear processes" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 14 "HPA008540: " "unprognostic (1.06e-1)" "unprognostic (1.64e-1)" "unprognostic (2.89e-1)" "unprognostic (1.98e-1)" "unprognostic (2.73e-1)" "unprognostic (5.25e-2)" "unprognostic (2.96e-2)" "unprognostic (8.30e-2)" "unprognostic (1.58e-1)" "unprognostic (1.22e-1)" "unprognostic (4.48e-2)" "unprognostic (1.92e-1)" "potential prognostic unfavorable (4.01e-5)" "unprognostic (3.98e-2)" "unprognostic (2.98e-2)" "unprognostic (1.13e-2)" "unprognostic (1.05e-2)" "unprognostic (9.72e-2)" "unprognostic (1.46e-2)" "unprognostic (5.26e-2)" "unprognostic (3.13e-2)" "unprognostic (6.53e-2)" "unprognostic (2.64e-1)" "unprognostic (1.53e-1)" "unprognostic (6.95e-2)" "unprognostic (4.48e-1)" "unprognostic (3.81e-2)" "unprognostic (2.27e-1)" "unprognostic (7.46e-2)" PACRG "FLJ32724, Glup, HAK005771, PARK2CRG" ENSG00000112530 "Parkin coregulated" Q96M98 6 162727132-163315500 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 28.6;testis: 23.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 746.7;Choroid plexus epithelial cells: 636.1;Endometrial ciliated cells: 582.3;Ependymal cells: 1417.8;Epididymal clear cells: 1202.3;Fallopian tube ciliated cells: 743.0;Lactotrophs: 763.1;Late spermatids: 684.4;Renal collecting duct intercalated cells: 1764.0;Respiratory ciliated cells: 1762.1;Respiratory ionocytes: 825.5;Sertoli cells: 569.5;Somatotrophs: 1090.8;Thyrotrophs: 1032.2" "Cell type enhanced" "Detected in all" "ependymal cell: 1537.2" "Cancer enriched" "Detected in many" 5 "Kidney Chromophobe (TCGA): 75.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Kidney - Intercalated cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066293 Enhanced Supported "Mitochondria,Mid piece,Principal piece,End piece" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 4 "Mid piece, Principal piece, End piece" Mitochondria "HPA066293: " "unprognostic (1.18e-1)" "unprognostic (4.32e-2)" "unprognostic (8.78e-2)" "unprognostic (2.96e-2)" "unprognostic (3.78e-2)" "unprognostic (1.78e-1)" "unprognostic (3.21e-1)" "unprognostic (1.88e-1)" "unprognostic (2.99e-1)" "unprognostic (1.47e-1)" "unprognostic (1.06e-1)" "potential prognostic favorable (4.14e-4)" "unprognostic (8.04e-3)" "unprognostic (7.01e-3)" "unprognostic (2.20e-2)" "unprognostic (4.56e-2)" "unprognostic (1.30e-1)" "unprognostic (4.03e-3)" "unprognostic (1.88e-1)" "unprognostic (2.36e-1)" "unprognostic (5.03e-2)" "unprognostic (2.57e-1)" "unprognostic (1.48e-1)" "unprognostic (3.42e-1)" "unprognostic (1.28e-2)" "unprognostic (4.51e-2)" "unprognostic (2.22e-1)" "unprognostic (7.77e-2)" "unprognostic (7.02e-2)" PACRGL "C4orf28, MGC29898" ENSG00000163138 "Parkin coregulated like" Q8N7B6 4 20696282-20752907 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 266.6;Late primary spermatocytes: 229.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054666 Approved Nucleoplasm,Vesicles NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 61: Non-specific - Transcription" "Cluster 17: Choroid plexus - Cilium" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 7: Non-specific - Transcription" 6 "Nucleoplasm, Vesicles" "HPA054666: " "unprognostic (1.88e-1)" "unprognostic (4.29e-2)" "unprognostic (1.65e-2)" "unprognostic (9.94e-2)" "potential prognostic favorable (8.42e-4)" "unprognostic (3.21e-3)" "unprognostic (1.40e-1)" "unprognostic (2.71e-2)" "unprognostic (4.24e-2)" "unprognostic (4.57e-2)" "potential prognostic favorable (8.86e-5)" "unprognostic (1.24e-2)" "unprognostic (9.25e-2)" "unprognostic (3.19e-2)" "unprognostic (2.17e-2)" "unprognostic (1.05e-1)" "unprognostic (1.11e-1)" "unprognostic (3.68e-2)" "unprognostic (7.52e-2)" "unprognostic (2.86e-1)" "unprognostic (2.12e-1)" "unprognostic (3.27e-3)" "unprognostic (1.00e-2)" "unprognostic (3.95e-1)" "unprognostic (1.92e-3)" "unprognostic (4.61e-3)" "unprognostic (6.52e-3)" "unprognostic (3.13e-3)" "unprognostic (1.73e-1)" "unprognostic (1.88e-2)" "unprognostic (1.40e-2)" PACS1 "FLJ10209, KIAA1175" ENSG00000175115 "Phosphofurin acidic cluster sorting protein 1" Q6VY07 11 66070272-66244744 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 875.4;Retinal horizontal cells: 849.4;Salivary acinar cells: 979.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Spleen - B-cells (Spleen), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038914, HPA075046" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA 10000 "Cluster 21: Neutrophils - Unknown function" "Cluster 35: Non-specific - Mixed function" "Cluster 33: Neurons - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 12 "Plasma membrane" "Nucleoplasm, Vesicles" "HPA038914: , HPA075046: " "unprognostic (1.68e-2)" "unprognostic (1.44e-1)" "unprognostic (4.92e-2)" "unprognostic (2.19e-2)" "unprognostic (8.03e-2)" "unprognostic (1.18e-2)" "unprognostic (7.25e-2)" "unprognostic (2.83e-1)" "unprognostic (1.39e-1)" "unprognostic (2.13e-1)" "unprognostic (3.06e-2)" "unprognostic (4.72e-2)" "unprognostic (3.88e-2)" "unprognostic (4.20e-3)" "unprognostic (1.47e-1)" "validated prognostic unfavorable (8.61e-4)" "validated prognostic unfavorable (5.88e-5)" "unprognostic (4.81e-2)" "unprognostic (1.89e-2)" "unprognostic (9.81e-3)" "unprognostic (1.30e-1)" "unprognostic (3.58e-3)" "unprognostic (7.46e-2)" "unprognostic (1.89e-1)" "unprognostic (1.98e-1)" "unprognostic (1.03e-3)" "unprognostic (4.30e-1)" "potential prognostic unfavorable (1.02e-4)" "unprognostic (1.23e-1)" "unprognostic (1.46e-2)" "unprognostic (1.04e-1)" PACS2 "KIAA0602, PACS1L" ENSG00000179364 "Phosphofurin acidic cluster sorting protein 2" Q86VP3 14 105300563-105398147 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Apoptosis, Host-virus interaction" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "brain: 95.7;skeletal muscle: 31.6" "Cell type enhanced" "Detected in many" "Late spermatids: 181.9;Oligodendrocytes: 202.8;Retinal horizontal cells: 190.3" "Cell type enhanced" "Detected in all" "oligodendrocyte: 284.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 2.2" "Group enriched" "Detected in many" 6 "dendritic cells: 2.2;monocytes: 1.8" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077892 Approved Mitochondria NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 80: Oligodendrocytes - Myelination" 3 Mitochondria "HPA077892: " "unprognostic (6.95e-2)" "unprognostic (6.34e-2)" "unprognostic (8.96e-3)" "unprognostic (4.96e-2)" "unprognostic (2.31e-1)" "unprognostic (1.32e-1)" "unprognostic (1.39e-1)" "unprognostic (5.06e-3)" "unprognostic (1.58e-1)" "unprognostic (1.61e-1)" "potential prognostic favorable (2.64e-6)" "unprognostic (1.78e-2)" "unprognostic (2.99e-3)" "potential prognostic unfavorable (2.09e-4)" "unprognostic (9.02e-2)" "unprognostic (2.57e-1)" "unprognostic (1.95e-1)" "unprognostic (4.27e-2)" "unprognostic (6.10e-2)" "unprognostic (7.34e-2)" "unprognostic (2.82e-1)" "unprognostic (1.58e-2)" "unprognostic (1.37e-2)" "unprognostic (2.29e-2)" "unprognostic (2.75e-2)" "unprognostic (1.68e-1)" "unprognostic (4.04e-1)" "unprognostic (1.75e-1)" "unprognostic (1.26e-1)" "unprognostic (4.18e-2)" "unprognostic (1.15e-1)" PACSIN1 SDPI ENSG00000124507 "Protein kinase C and casein kinase substrate in neurons 1" Q9BY11 6 34466061-34535229 "Plasma proteins, Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 28 "brain: 238.9;retina: 59.7" "Group enriched" "Detected in many" 4 "Brain excitatory neurons: 76.5;Brain inhibitory neurons: 66.9;Cone photoreceptor cells: 138.7;Other brain neurons: 55.9;pDCs: 188.2;Retinal amacrine cells: 133.7;Retinal bipolar cells: 90.4;Retinal ganglion cells: 54.1;Retinal horizontal cells: 62.1;Rod photoreceptor cells: 175.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 8.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "plasmacytoid DC: 15.8" "Lineage enriched" "Detected in many" 4 "dendritic cells: 15.8" "Cancer enhanced" "Detected in many" "Myeloma: 21.9;prostate cancer: 9.9" "Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Corticotropes, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Spleen - B-cells (Spleen), Stomach - Parietal cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009929, HPA028852, HPA055491" Enhanced Approved Nucleoplasm,Nucleoli,Vesicles NA NA 16000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 24: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 37 "Nucleoplasm, Vesicles" Nucleoli "CAB009929: , HPA028852: , HPA055491: " "unprognostic (1.16e-1)" "unprognostic (3.32e-1)" "unprognostic (9.86e-2)" "unprognostic (1.04e-2)" "unprognostic (4.26e-2)" "unprognostic (1.95e-1)" "unprognostic (1.45e-1)" "unprognostic (1.53e-1)" "unprognostic (2.69e-1)" "unprognostic (4.57e-2)" "unprognostic (7.00e-2)" "unprognostic (4.03e-1)" PACSIN2 SDPII ENSG00000100266 "Protein kinase C and casein kinase substrate in neurons 2" Q9UNF0 22 42835412-43015149 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 577.8;Neutrophils: 1361.0;Pancreatic acinar cells: 524.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 96.2" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Pituitary gland - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049854, HPA056520" Enhanced Approved "Nuclear speckles,Vesicles,Plasma membrane,Primary cilium,Centriolar satellite" NA NA 1400000 "Cluster 7: Non-specific - Innate immune response" "Cluster 8: Pancreas - Proteolysis" "Cluster 49: Hindbrain - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 24: Neutrophils - Innate immunity signal integration" 48 "Nuclear speckles, Plasma membrane" "Vesicles, Primary cilium, Centriolar satellite" "HPA049854: , HPA056520: " "unprognostic (2.67e-3)" "unprognostic (4.28e-2)" "unprognostic (9.66e-2)" "unprognostic (2.74e-2)" "unprognostic (2.92e-2)" "unprognostic (1.66e-3)" "unprognostic (1.11e-2)" "unprognostic (3.95e-2)" "unprognostic (1.82e-1)" "unprognostic (4.21e-1)" "validated prognostic favorable (3.95e-7)" "validated prognostic favorable (2.02e-5)" "unprognostic (1.99e-3)" "potential prognostic unfavorable (2.88e-4)" "unprognostic (2.34e-2)" "unprognostic (3.03e-1)" "unprognostic (1.25e-1)" "unprognostic (8.54e-2)" "unprognostic (2.17e-2)" "unprognostic (5.80e-2)" "unprognostic (1.92e-1)" "unprognostic (2.20e-2)" "unprognostic (2.56e-1)" "unprognostic (1.50e-1)" "unprognostic (3.27e-2)" "unprognostic (3.43e-2)" "unprognostic (2.24e-1)" "unprognostic (1.58e-1)" "unprognostic (1.85e-1)" "unprognostic (7.72e-3)" "unprognostic (3.78e-2)" PACSIN3 SDPIII ENSG00000165912 "Protein kinase C and casein kinase substrate in neurons 3" Q9UKS6 11 47177522-47186443 "Plasma proteins, Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "heart muscle: 155.2;skeletal muscle: 450.8;tongue: 260.7" "Cell type enhanced" "Detected in many" "Breast lactating cells: 64.1;Esophageal apical cells: 176.1;Esophageal basal cells: 102.1;Esophageal suprabasal cells: 106.6;Extravillous trophoblasts: 70.1;Migrating cytotrophoblasts: 62.7;Smooth muscle cells: 65.9;Thymic myoid cells: 110.1" "Cell type enhanced" "Detected in many" "astrocyte: 8.8;oligodendrocyte: 14.0;vascular associated smooth muscle cell: 9.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039480, HPA043904" Approved Approved Supported "Plasma membrane,Cytosol" NA NA 6200 "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 46 Cytosol "Plasma membrane" "HPA039480: , HPA043904: " "unprognostic (1.29e-1)" "unprognostic (6.97e-2)" "unprognostic (2.60e-1)" "unprognostic (3.38e-1)" "unprognostic (2.12e-1)" "unprognostic (2.69e-1)" "unprognostic (1.66e-1)" "potential prognostic unfavorable (8.33e-4)" "unprognostic (1.97e-2)" "unprognostic (1.39e-2)" "unprognostic (2.68e-3)" "unprognostic (1.25e-3)" "potential prognostic favorable (1.32e-4)" "unprognostic (5.63e-2)" "potential prognostic unfavorable (1.58e-4)" "unprognostic (4.87e-2)" "unprognostic (2.57e-2)" "unprognostic (1.39e-1)" "unprognostic (5.76e-3)" "unprognostic (3.08e-3)" "unprognostic (1.27e-1)" "unprognostic (5.73e-3)" "unprognostic (5.92e-3)" "unprognostic (1.29e-1)" "unprognostic (2.30e-1)" "unprognostic (1.11e-1)" "unprognostic (1.17e-1)" "unprognostic (1.73e-1)" "unprognostic (1.46e-1)" "unprognostic (1.10e-1)" "unprognostic (2.13e-1)" PADI1 "HPAD10, PAD1, PDI, PDI1" ENSG00000142623 "Peptidyl arginine deiminase 1" Q9ULC6 1 17205128-17246007 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "esophagus: 84.3" "Cell type enhanced" "Detected in some" "Esophageal apical cells: 5.9;Loop of henle epithelial cells: 2.5;Microglia: 3.0;Other brain neurons: 1.1;Papillary tip epithelial cells: 11.1;Salivary duct cells: 1.8" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 3.8;lower rhombic lip: 6.7;thalamic excitatory: 3.1" "Cancer enhanced" "Detected in some" "Pancreatic Adenocarcinoma (TCGA): 6.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Bile duct cancer: 14.6;colorectal cancer: 5.3;Gallbladder cancer: 19.4;ovarian cancer: 9.2;pancreatic cancer: 13.2" "Prostate - Urothelial cells, Skin - Inner root sheath cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA062294 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 15: Kidney cancer - Membrane components" "Cluster 109: Neurons - Neuronal signaling" 1 Cytosol Nucleoplasm "HPA062294: " "unprognostic (1.23e-2)" "unprognostic (2.40e-1)" "unprognostic (1.45e-1)" "unprognostic (2.79e-3)" "unprognostic (8.70e-2)" "unprognostic (1.10e-1)" "unprognostic (1.87e-1)" "unprognostic (2.32e-1)" "potential prognostic unfavorable (2.49e-4)" "unprognostic (3.22e-1)" PADI2 "KIAA0994, PDI2" ENSG00000117115 "Peptidyl arginine deiminase 2" Q9Y2J8 1 17066761-17119451 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 236.1;skeletal muscle: 292.0;tongue: 459.8" "Cell type enhanced" "Detected in many" "Colonocytes: 225.7;Cone photoreceptor cells: 231.9;Goblet cells: 113.5;Macrophages: 91.4;Microglia: 201.6;Müller glia: 86.2;Myonuclei: 231.4;Neutrophil progenitors: 82.2;Neutrophils: 218.9;Oligodendrocytes: 162.1;Rod photoreceptor cells: 121.5" "Cell type enhanced" "Detected in many" "astrocyte: 118.2;central nervous system macrophage: 286.0;committed oligodendrocyte precursor: 117.5;oligodendrocyte: 223.6" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 51.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "eosinophil: 43.4;neutrophil: 100.9" "Lineage enriched" "Detected in many" 6 "granulocytes: 100.9" "Cancer enhanced" "Detected in many" "breast cancer: 46.6" "Adipose visceral - Neutrophils, Colon - Colon enterocytes, Heart muscle - Neutrophils, Kidney - Ascending Loop of Henle cells, Liver - Neutrophils, Pituitary gland - Undifferentiated cells (Pituitary gland), Skin - Eccrine sweat gland cells, Spleen - Neutrophils_2, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047735 Enhanced NA NA 9700 "Cluster 21: Neutrophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 27: Breast cancer - Unknown function" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 1 "HPA047735: " "unprognostic (1.04e-1)" "unprognostic (3.97e-2)" "unprognostic (1.34e-1)" "unprognostic (6.95e-2)" "unprognostic (1.28e-2)" "unprognostic (8.90e-2)" "unprognostic (4.91e-2)" "unprognostic (2.56e-1)" "unprognostic (6.47e-2)" "unprognostic (2.89e-1)" "unprognostic (4.69e-2)" "unprognostic (1.44e-1)" "unprognostic (1.07e-2)" "unprognostic (2.29e-1)" "unprognostic (5.66e-2)" "unprognostic (1.18e-1)" "unprognostic (1.88e-1)" "unprognostic (2.26e-1)" "unprognostic (2.67e-3)" "unprognostic (7.97e-2)" "unprognostic (8.77e-2)" "unprognostic (3.87e-1)" "unprognostic (2.71e-1)" "unprognostic (2.91e-2)" "potential prognostic unfavorable (4.46e-4)" "unprognostic (6.24e-2)" "unprognostic (4.80e-2)" "unprognostic (4.52e-2)" "unprognostic (5.04e-2)" "unprognostic (2.25e-2)" PADI3 PDI3 ENSG00000142619 "Peptidyl arginine deiminase 3" Q9ULW8 1 17249098-17284233 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "esophagus: 16.4;urinary bladder: 25.6" "Group enriched" "Detected in some" 29 "Esophageal apical cells: 4.4;Papillary tip epithelial cells: 17.3;Prostatic hillock cells: 8.6;Urothelial cells: 9.9" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 31.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 19.1;Kidney cancer: 20.5" "Prostate - Urothelial cells, Skin - Hair cortex cells, Skin - Inner root sheath cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA043739 Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 15: Kidney cancer - Membrane components" "Cluster 69: Urothelial cells - Basic cellular functions" 13 "Vesicles, Cytosol" Nucleoplasm "HPA043739: " "unprognostic (4.54e-2)" "unprognostic (7.55e-2)" "unprognostic (1.56e-1)" "unprognostic (1.45e-1)" "potential prognostic favorable (8.00e-4)" "unprognostic (8.03e-2)" "unprognostic (8.53e-3)" "unprognostic (1.09e-1)" "unprognostic (9.48e-2)" "unprognostic (8.94e-2)" "unprognostic (3.12e-3)" "unprognostic (2.01e-2)" "unprognostic (1.45e-1)" PADI4 "PAD, PADI5, PDI4, PDI5" ENSG00000159339 "Peptidyl arginine deiminase 4" Q9UM07 1 17308195-17364004 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Immunity, Innate immunity, Transcription, Transcription regulation" "Chromatin regulator, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "bone marrow: 99.4;lymphoid tissue: 28.9" "Group enriched" "Detected in some" 7 "Neutrophil progenitors: 215.0;Neutrophils: 161.5" "Cell type enhanced" "Detected in some" "leukocyte: 4.7;upper-layer intratelencephalic: 3.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 8 "basophil: 80.1;classical monocyte: 71.3;eosinophil: 97.7;neutrophil: 183.5" "Group enriched" "Detected in all" 9 "granulocytes: 183.5;monocytes: 71.3" "Cancer enriched" "Detected in single" 10 "Leukemia: 3.7" "Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophils_2, Pituitary gland - Neutrophils, Skeletal muscle - Neutrophils, Spleen - Neutrophils_2, Stomach - Neutrophils, Thyroid gland - Neutrophils" "Not detected" "Not detected" "Not detected" "Not detected" "HPA017007, HPA042825" Enhanced NA NA 49000 "Cluster 21: Neutrophils - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 53: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 15 "HPA017007: , HPA042825: " "unprognostic (4.03e-2)" PADI6 ENSG00000276747 "Peptidyl arginine deiminase 6" Q6TGC4 1 17372196-17401699 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 55 "ovary: 5.5" "Cell type enriched" "Detected in single" 282 "Oocytes: 82.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Skin - Inner root sheath cells" "Region enhanced" "Detected in single" "white matter: 2.4" "Not detected" "Not detected" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 41: Oocytes - Oogenesis" 4 PAEP "GD, GdA, GdF, GdS, MGC138509, MGC142288, PAEG, PEP, PP14" ENSG00000122133 "Progestagen associated endometrial protein" P09466 9 135561756-135566955 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "endometrium 1: 240.5" "Cell type enriched" "Detected in some" 29 "Endometrial glandular cells: 17493.3" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "Skin Cutaneous Melanoma (TCGA): 804.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 3.1;neutrophil: 1.4" "Lineage enriched" "Detected in single" 6 "granulocytes: 3.1" "Group enriched" "Detected in many" 6 "skin cancer: 32.2;thyroid cancer: 74.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB016762, HPA020108, HPA029473" Enhanced "Secreted in female reproductive system" "No annotated function" NA NA 500000 "Cluster 20: Non-specific - DNA binding" "Cluster 75: Ovary - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 51: Secretory epithelial cells - Mixed function" 14 "CAB016762: , HPA020108: , HPA029473: " "potential prognostic unfavorable (7.56e-5)" "unprognostic (1.44e-1)" "unprognostic (2.19e-1)" "unprognostic (1.92e-1)" "unprognostic (1.73e-1)" "unprognostic (1.70e-1)" "unprognostic (4.17e-2)" "unprognostic (1.58e-3)" "validated prognostic unfavorable (5.78e-13)" "validated prognostic unfavorable (5.12e-7)" "potential prognostic unfavorable (5.28e-4)" "potential prognostic unfavorable (1.95e-6)" "unprognostic (8.04e-2)" "unprognostic (1.57e-1)" "unprognostic (9.44e-2)" "unprognostic (1.65e-3)" "unprognostic (4.23e-2)" "unprognostic (6.78e-3)" "unprognostic (3.09e-2)" "unprognostic (8.58e-3)" "potential prognostic unfavorable (8.37e-4)" "unprognostic (4.48e-1)" "unprognostic (1.09e-1)" "unprognostic (3.43e-2)" "unprognostic (5.79e-3)" "unprognostic (8.15e-2)" "unprognostic (3.21e-1)" PAF1 "F23149_1, FLJ11123, PD2" ENSG00000006712 "PAF1 homolog, Paf1/RNA polymerase II complex component" Q8N7H5 19 39385629-39391154 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 157.3;Late primary spermatocytes: 137.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041875, HPA071954" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles" NA NA "Cluster 32: Basophils - Transcription" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 4: Non-specific - Transcription" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 79 Nucleoplasm "Nucleoli fibrillar center, Vesicles" "HPA041875: , HPA071954: " "unprognostic (5.82e-3)" "unprognostic (7.57e-2)" "unprognostic (2.68e-1)" "unprognostic (4.91e-2)" "unprognostic (6.29e-2)" "unprognostic (7.80e-2)" "unprognostic (2.05e-1)" "unprognostic (1.10e-1)" "unprognostic (1.25e-1)" "unprognostic (8.60e-2)" "potential prognostic favorable (3.74e-5)" "unprognostic (3.07e-3)" "unprognostic (3.02e-2)" "potential prognostic unfavorable (3.38e-4)" "unprognostic (5.89e-2)" "unprognostic (6.32e-2)" "unprognostic (2.39e-1)" "unprognostic (4.34e-3)" "unprognostic (2.93e-1)" "unprognostic (1.01e-1)" "unprognostic (1.61e-1)" "unprognostic (2.45e-2)" "unprognostic (3.02e-2)" "unprognostic (9.17e-2)" "unprognostic (2.55e-1)" "unprognostic (5.01e-2)" "unprognostic (3.05e-2)" "unprognostic (9.30e-2)" "unprognostic (2.64e-1)" "unprognostic (1.35e-1)" "unprognostic (9.77e-2)" PAFAH1B1 "LIS1, MDCR, MDS, NudF, PAFAH" ENSG00000007168 "Platelet activating factor acetylhydrolase 1b regulatory subunit 1" P43034 17 2593210-2685615 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Lipid degradation, Lipid metabolism, Mitosis, Neurogenesis, Transport" "Developmental protein" "Disease variant, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 3382.9;Neutrophils: 947.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004489, HPA020036" Approved Supported "Centrosome,Mid piece" NA NA 1300000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 1: Neurons - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 85 Centrosome "Mid piece" "CAB004489: , HPA020036: " "unprognostic (1.24e-1)" "unprognostic (3.67e-3)" "unprognostic (8.74e-3)" "unprognostic (1.58e-1)" "unprognostic (6.00e-2)" "unprognostic (5.56e-2)" "unprognostic (2.62e-1)" "unprognostic (4.14e-3)" "unprognostic (1.81e-3)" "unprognostic (2.19e-1)" "potential prognostic favorable (6.98e-8)" "unprognostic (3.38e-3)" "unprognostic (6.00e-2)" "unprognostic (9.62e-2)" "unprognostic (3.94e-2)" "unprognostic (1.30e-1)" "unprognostic (4.16e-2)" "unprognostic (2.31e-2)" "unprognostic (7.50e-2)" "unprognostic (2.48e-2)" "unprognostic (4.09e-2)" "unprognostic (1.17e-1)" "potential prognostic unfavorable (9.16e-4)" "unprognostic (1.47e-1)" "unprognostic (2.68e-1)" "unprognostic (2.39e-1)" "unprognostic (1.96e-1)" "unprognostic (2.57e-2)" "unprognostic (3.95e-1)" "unprognostic (9.09e-2)" "unprognostic (5.78e-2)" PAFAH1B2 ENSG00000168092 "Platelet activating factor acetylhydrolase 1b catalytic subunit 2" P68402 11 117144284-117176894 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051836 Approved Supported "Nucleoli,Plasma membrane,Cytosol" NA NA 220000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 11 Cytosol "Nucleoli, Plasma membrane" "HPA051836: " "unprognostic (3.65e-2)" "unprognostic (1.86e-3)" "unprognostic (7.30e-2)" "unprognostic (4.58e-3)" "unprognostic (1.73e-1)" "unprognostic (2.29e-2)" "unprognostic (1.41e-1)" "unprognostic (1.08e-2)" "unprognostic (1.10e-2)" "unprognostic (8.07e-2)" "unprognostic (1.28e-3)" "unprognostic (3.00e-3)" "unprognostic (3.66e-2)" "unprognostic (1.57e-3)" "unprognostic (6.29e-3)" "unprognostic (1.31e-3)" "unprognostic (1.39e-2)" "unprognostic (1.67e-1)" "unprognostic (2.41e-1)" "unprognostic (1.78e-1)" "unprognostic (3.03e-2)" "unprognostic (1.21e-3)" "unprognostic (4.50e-3)" "unprognostic (2.35e-1)" "unprognostic (9.84e-2)" "unprognostic (2.77e-1)" "unprognostic (5.38e-2)" "unprognostic (1.60e-1)" "unprognostic (2.87e-1)" "unprognostic (2.58e-1)" "unprognostic (1.70e-3)" PAFAH1B3 ENSG00000079462 "Platelet activating factor acetylhydrolase 1b catalytic subunit 3" Q15102 19 42297033-42303546 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 258.1;Esophageal basal cells: 164.8;Oocytes: 225.6;Undifferentiated spermatogonia: 150.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Outer root sheath cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035639 Uncertain Approved "Intermediate filaments" NA NA 300000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 27: Cerebellum - Synaptic function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 4: Non-specific - Transcription" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 17 "Intermediate filaments" "HPA035639: " "unprognostic (2.89e-2)" "unprognostic (2.11e-1)" "unprognostic (8.22e-2)" "unprognostic (7.14e-3)" "unprognostic (1.23e-1)" "unprognostic (8.27e-2)" "unprognostic (4.81e-2)" "unprognostic (3.22e-1)" "unprognostic (4.90e-2)" "unprognostic (2.98e-2)" "unprognostic (1.24e-2)" "unprognostic (1.61e-1)" "unprognostic (3.55e-1)" "validated prognostic unfavorable (7.69e-5)" "validated prognostic unfavorable (5.77e-5)" "potential prognostic unfavorable (1.45e-4)" "unprognostic (1.41e-2)" "potential prognostic favorable (8.41e-4)" "unprognostic (1.73e-1)" "unprognostic (7.56e-2)" "unprognostic (3.04e-1)" "unprognostic (2.52e-1)" "unprognostic (1.30e-1)" "unprognostic (2.00e-1)" "unprognostic (3.29e-1)" "unprognostic (9.57e-3)" "unprognostic (1.70e-1)" "unprognostic (2.54e-1)" "unprognostic (4.91e-2)" "unprognostic (1.02e-1)" "unprognostic (1.92e-1)" PAFAH2 HSD-PLA2 ENSG00000158006 "Platelet activating factor acetylhydrolase 2" Q99487 1 25959767-25998117 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 45.4" "Cell type enhanced" "Detected in many" "Parietal cells: 49.5;pDCs: 51.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018157 Approved NA Yes "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 11: White matter - Signal transduction" "Cluster 49: HMC-1 - Innate immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" "HPA018157: " "unprognostic (8.33e-2)" "unprognostic (6.25e-2)" "unprognostic (4.09e-1)" "unprognostic (5.12e-2)" "unprognostic (2.76e-2)" "unprognostic (2.27e-2)" "unprognostic (9.19e-2)" "unprognostic (2.86e-1)" "unprognostic (2.90e-1)" "unprognostic (1.18e-2)" "validated prognostic favorable (1.65e-14)" "validated prognostic favorable (5.35e-5)" "potential prognostic favorable (3.26e-4)" "unprognostic (1.36e-1)" "unprognostic (8.71e-3)" "unprognostic (2.07e-1)" "unprognostic (1.00e-1)" "unprognostic (5.94e-2)" "unprognostic (2.38e-1)" "unprognostic (4.94e-2)" "unprognostic (1.10e-2)" "unprognostic (1.17e-1)" "unprognostic (1.30e-1)" "unprognostic (2.87e-1)" "unprognostic (7.97e-2)" "unprognostic (9.02e-3)" "unprognostic (1.62e-1)" "unprognostic (1.50e-1)" "unprognostic (2.24e-1)" "unprognostic (3.42e-2)" "unprognostic (8.71e-2)" PAG1 "CBP, PAG" ENSG00000076641 "Phosphoprotein membrane anchor with glycosphingolipid microdomains 1" Q9NWQ8 8 80967810-81112068 "Predicted intracellular proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Mast cells: 612.7;Melanocytes: 842.8;Microglia: 548.9;monocytes: 466.6;Neutrophil progenitors: 1964.4;Neutrophils: 2606.1" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 712.7;pericyte: 609.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "lymphoma: 25.9" "Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001632, HPA066527" Enhanced Supported "Vesicles,Plasma membrane" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 15 "Vesicles, Plasma membrane" "HPA001632: , HPA066527: " "unprognostic (9.22e-2)" "unprognostic (1.59e-1)" "unprognostic (1.16e-1)" "unprognostic (2.09e-3)" "unprognostic (8.08e-2)" "unprognostic (1.92e-1)" "unprognostic (1.91e-1)" "unprognostic (5.23e-2)" "unprognostic (3.38e-2)" "unprognostic (6.91e-3)" "unprognostic (7.77e-3)" "unprognostic (1.47e-1)" "unprognostic (4.54e-2)" "unprognostic (1.35e-2)" "unprognostic (1.51e-1)" "unprognostic (2.29e-2)" "unprognostic (2.42e-1)" "unprognostic (2.09e-2)" "unprognostic (5.25e-1)" "unprognostic (3.01e-1)" "unprognostic (1.07e-1)" "unprognostic (2.59e-1)" "unprognostic (2.12e-2)" "unprognostic (2.82e-2)" "unprognostic (1.19e-2)" "unprognostic (1.13e-2)" "unprognostic (1.44e-1)" "unprognostic (1.99e-1)" "unprognostic (2.25e-2)" "unprognostic (1.47e-1)" "unprognostic (8.05e-2)" PAGE1 "CT16.3, GAGE-9, GAGEB1, PAGE-1" ENSG00000068985 "PAGE family member 1" O75459 X 49687447-49695984 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 159 "testis: 17.0" "Group enriched" "Detected in some" 6 "Differentiating spermatogonia: 203.5;Early primary spermatocytes: 268.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 15.8;Skin Cutaneous Melanoma (TCGA): 10.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 58.6;skin cancer: 19.6" HPA003473 Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Mitochondria" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 14 "Nucleoli fibrillar center" "Nucleoplasm, Mitochondria" "HPA003473: " "potential prognostic unfavorable (5.33e-7)" "unprognostic (1.91e-2)" "unprognostic (5.35e-1)" "unprognostic (3.79e-1)" "unprognostic (1.53e-1)" "unprognostic (2.39e-1)" "unprognostic (1.61e-1)" "unprognostic (5.17e-1)" PAGE2 "CT16.4, GAGEC2, MGC62094, PAGE-2" ENSG00000234068 "PAGE family member 2" Q7Z2X7 X 55089018-55092842 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 41 "testis: 28.3" "Group enriched" "Detected in some" 13 "Differentiating spermatogonia: 177.7;Early primary spermatocytes: 195.9;Undifferentiated spermatogonia: 149.4" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 150.9;thyroid cancer: 75.6" "Testis - Spermatogonia" HPA052619 Supported NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 20: Myeloma - Immune response" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 2 "HPA052619: " "unprognostic (1.35e-1)" "unprognostic (2.74e-1)" "unprognostic (3.15e-1)" "unprognostic (1.98e-1)" "unprognostic (9.11e-1)" "potential prognostic unfavorable (1.56e-5)" "potential prognostic unfavorable (6.88e-4)" "unprognostic (2.60e-1)" "unprognostic (2.22e-1)" "unprognostic (6.48e-1)" "unprognostic (7.29e-3)" "unprognostic (9.29e-2)" "unprognostic (6.62e-2)" "unprognostic (3.05e-2)" "unprognostic (5.12e-1)" "unprognostic (4.02e-1)" "unprognostic (1.76e-1)" "unprognostic (7.53e-3)" PAGE2B CT16.5 ENSG00000238269 "PAGE family member 2B" Q5JRK9 X 55075030-55078909 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "testis: 51.8" "Group enriched" "Detected in some" 6 "Differentiating spermatogonia: 306.9;Early primary spermatocytes: 304.7;Undifferentiated spermatogonia: 262.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 24.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 151.8;thyroid cancer: 71.4" "Testis - Spermatogonia" HPA052619 Supported NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 20: Myeloma - Immune response" "Cluster 106: Spermatogonia - Spermatogonial differentiation" "HPA052619: " "unprognostic (1.37e-1)" "potential prognostic unfavorable (9.98e-4)" "unprognostic (2.39e-1)" "unprognostic (5.30e-3)" "unprognostic (2.71e-1)" "unprognostic (3.92e-1)" "potential prognostic unfavorable (1.97e-5)" "unprognostic (4.28e-2)" "potential prognostic unfavorable (9.68e-4)" "unprognostic (2.17e-2)" "unprognostic (3.04e-1)" "unprognostic (1.84e-1)" "unprognostic (2.63e-1)" "unprognostic (1.86e-1)" "unprognostic (5.36e-2)" "unprognostic (2.80e-1)" "unprognostic (1.88e-1)" "unprognostic (2.72e-1)" "unprognostic (4.73e-2)" PAGE3 "CT16.6, GAGED1, PAGE-3" ENSG00000204279 "PAGE family member 3" Q5JUK9 X 55258415-55264916 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 73 "testis: 7.2" "Group enriched" "Detected in some" 11 "Early spermatids: 125.1;Late spermatids: 430.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "HPA045032, HPA062248" Uncertain Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 27: Breast cancer - Unknown function" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 4 "Nuclear speckles" Nucleoplasm "HPA045032: , HPA062248: " PAGE4 "CT16.7, GAGEC1, PAGE-4" ENSG00000101951 "PAGE family member 4" O60829 X 49829260-49834264 "Cancer-related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "epididymis: 822.3;placenta: 959.5" "Group enriched" "Detected in some" 52 "Cytotrophoblasts: 16497.9;Migrating cytotrophoblasts: 8434.0;Syncytiotrophoblasts: 9302.1" "Cell type enhanced" "Detected in single" "hippocampal CA4: 1.2" "Group enriched" "Detected in some" 13 "Liver Hepatocellular Carcinoma (TCGA): 85.5;Prostate Adenocarcinoma (TCGA): 48.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "colorectal cancer: 5.3;Gastric cancer: 15.4;Myeloma: 7.7" "Not detected" "Not detected" HPA023880 Enhanced Approved "Golgi apparatus,Vesicles" NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 2 Vesicles "Golgi apparatus" "HPA023880: " "unprognostic (3.59e-1)" "unprognostic (1.38e-2)" "unprognostic (5.52e-1)" "unprognostic (4.99e-2)" "unprognostic (1.60e-3)" "unprognostic (1.59e-1)" "unprognostic (1.25e-1)" PAGE5 "CT16.1, CT16.2, PAGE-5" ENSG00000158639 "PAGE family member 5" Q96GU1 X 55220346-55224108 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 26 "testis: 25.6" "Group enriched" "Detected in some" 6 "Differentiating spermatogonia: 113.4;Early primary spermatocytes: 169.8;Undifferentiated spermatogonia: 122.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 41.0" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 1.9" "Lineage enriched" "Detected in single" 13 "T-cells: 1.9" "Cancer enhanced" "Detected in many" "Myeloma: 233.0;thyroid cancer: 105.2" "Liver - Hepatocytes" "HPA052619, HPA055869" Supported Approved Mitochondria NA NA "Cluster 11: T-cells - Unknown function" "Cluster 6: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 1 Mitochondria "HPA052619: , HPA055869: " "unprognostic (4.96e-2)" "unprognostic (3.15e-1)" "unprognostic (4.75e-2)" "unprognostic (1.86e-1)" "unprognostic (3.48e-2)" "unprognostic (3.57e-1)" "unprognostic (1.65e-2)" "unprognostic (2.88e-1)" "unprognostic (3.95e-2)" "unprognostic (2.12e-1)" "unprognostic (1.43e-3)" "unprognostic (1.33e-1)" "unprognostic (2.70e-1)" PAGR1 "C16orf53, GAS, MGC4606, PA1" ENSG00000280789 "PAXIP1 associated glutamate rich protein 1" Q9BTK6 16 29816152-29822489 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 54.3" "Cell type enriched" "Detected in some" 8 "Epicardial cells: 18.2" "Cell type enhanced" "Detected in many" "upper rhombic lip: 4.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Kidney - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041440, HPA043608" Uncertain NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 64: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 54: Non-specific - Transcription" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 18 "HPA041440: , HPA043608: " "unprognostic (1.79e-1)" "unprognostic (6.78e-2)" "unprognostic (4.02e-2)" "unprognostic (1.21e-1)" "unprognostic (3.66e-2)" "unprognostic (1.97e-1)" "unprognostic (3.77e-2)" "unprognostic (1.87e-1)" "potential prognostic favorable (5.08e-5)" "unprognostic (4.05e-1)" "unprognostic (1.00e-1)" "unprognostic (1.86e-2)" "unprognostic (1.91e-2)" "unprognostic (1.35e-1)" "unprognostic (3.22e-2)" "unprognostic (1.93e-3)" "unprognostic (1.60e-1)" "unprognostic (6.01e-3)" "unprognostic (1.67e-1)" "unprognostic (1.68e-2)" "unprognostic (9.21e-2)" "unprognostic (2.74e-1)" "unprognostic (1.74e-1)" "unprognostic (1.76e-1)" "unprognostic (9.41e-2)" "unprognostic (7.47e-3)" PAH PH ENSG00000171759 "Phenylalanine hydroxylase" P00439 12 102836889-102958410 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Phenylalanine catabolism" "Allosteric enzyme, Monooxygenase, Oxidoreductase" "Disease variant, FDA approved drug targets, Phenylketonuria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 12 "kidney: 463.6;liver: 1316.7" "Cell type enhanced" "Detected in many" "Cholangiocytes: 264.0;Corticotrophs: 102.3;Early spermatids: 184.7;Hepatocytes: 1063.0;Late primary spermatocytes: 143.2;Proximal tubule cells: 434.8" "Cell type enhanced" "Detected in many" "midbrain-derived inhibitory: 35.4" "Cancer enriched" "Detected in many" 13 "Liver Hepatocellular Carcinoma (TCGA): 322.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "liver cancer: 43.8" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA028407, HPA031642" Enhanced Approved "Endoplasmic reticulum,Vesicles" No NA 9900 "Cluster 16: Liver & Kidney - Metabolism" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 18: Liver cancer - Metabolism" "Cluster 88: Proximal tubular cells - Transmembrane transport" 1 "Endoplasmic reticulum, Vesicles" "HPA028407: , HPA031642: " "unprognostic (1.51e-1)" "unprognostic (1.54e-1)" "unprognostic (5.18e-1)" "unprognostic (8.74e-2)" "unprognostic (1.21e-1)" "unprognostic (5.93e-2)" "potential prognostic favorable (4.17e-5)" "unprognostic (2.19e-3)" "unprognostic (2.89e-1)" "potential prognostic favorable (2.34e-4)" "unprognostic (1.50e-3)" "unprognostic (1.63e-1)" "unprognostic (7.88e-2)" "unprognostic (1.06e-1)" "potential prognostic favorable (6.57e-4)" "unprognostic (9.79e-3)" "unprognostic (1.13e-1)" "unprognostic (1.74e-1)" "unprognostic (1.87e-2)" "unprognostic (3.35e-2)" "unprognostic (1.89e-1)" PAICS "ADE2H1, AIRC, PAIS" ENSG00000128050 "Phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase" P22234 4 56435741-56464578 "Disease related genes, Enzymes, Essential proteins, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Purine biosynthesis" "Decarboxylase, Ligase, Lyase, Multifunctional enzyme" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 178.0;Erythrocyte progenitors: 217.2;Esophageal basal cells: 184.0;Extravillous trophoblasts: 183.5;Migrating cytotrophoblasts: 204.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Macrophages, Liver - Hepatocytes, Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035895, HPA041538" Approved Approved Cytosol Yes No 1200000 "Cluster 18: Non-specific - Translation" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 19: Astrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 17: Non-specific - RNA processing" 35 Cytosol "HPA035895: , HPA041538: " "unprognostic (6.37e-2)" "unprognostic (2.86e-3)" "unprognostic (2.60e-1)" "unprognostic (5.40e-3)" "unprognostic (3.11e-2)" "unprognostic (2.31e-1)" "unprognostic (6.71e-2)" "unprognostic (5.39e-3)" "unprognostic (2.69e-3)" "unprognostic (1.42e-3)" "unprognostic (2.18e-3)" "unprognostic (2.31e-1)" "unprognostic (1.17e-3)" "potential prognostic unfavorable (1.57e-5)" "unprognostic (4.04e-3)" "validated prognostic unfavorable (5.52e-5)" "validated prognostic unfavorable (2.41e-4)" "unprognostic (2.69e-1)" "unprognostic (2.08e-2)" "unprognostic (1.21e-2)" "unprognostic (1.69e-1)" "potential prognostic unfavorable (1.70e-5)" "unprognostic (9.14e-2)" "unprognostic (8.93e-2)" "potential prognostic favorable (2.73e-4)" "unprognostic (4.36e-2)" "unprognostic (8.30e-3)" "unprognostic (7.06e-2)" "unprognostic (1.68e-1)" "unprognostic (2.47e-3)" "unprognostic (7.96e-3)" PAIP1 ENSG00000172239 "Poly(A) binding protein interacting protein 1" Q9H074 5 43526267-43557758 "Predicted intracellular proteins" "Host-virus interaction, Translation regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 534.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA073653, HPA076187" Approved Enhanced "Plasma membrane,Cytosol" No No 95000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 29: Non-specific - Unknown function" "Cluster 41: Oocytes - Oogenesis" 26 "Plasma membrane, Cytosol" "HPA073653: , HPA076187: " "unprognostic (1.90e-1)" "unprognostic (1.25e-2)" "potential prognostic unfavorable (7.11e-4)" "unprognostic (3.37e-2)" "unprognostic (2.81e-1)" "unprognostic (2.95e-1)" "unprognostic (1.02e-1)" "unprognostic (5.30e-2)" "unprognostic (2.99e-1)" "potential prognostic unfavorable (1.80e-6)" "unprognostic (1.23e-2)" "unprognostic (1.74e-1)" "unprognostic (2.99e-1)" "potential prognostic unfavorable (9.33e-7)" "unprognostic (2.33e-2)" "unprognostic (1.84e-2)" "unprognostic (1.06e-2)" "unprognostic (4.47e-1)" "unprognostic (2.76e-1)" "unprognostic (1.24e-1)" "unprognostic (3.16e-2)" "potential prognostic unfavorable (6.01e-4)" "unprognostic (7.42e-3)" "unprognostic (6.37e-2)" "unprognostic (1.24e-2)" "unprognostic (3.61e-1)" "unprognostic (7.54e-2)" "unprognostic (1.70e-2)" "unprognostic (3.30e-2)" "unprognostic (1.36e-1)" "unprognostic (9.72e-2)" PAIP2 PAIP2A ENSG00000120727 "Poly(A) binding protein interacting protein 2" Q9BPZ3 5 139341587-139369720 "Predicted intracellular proteins" "Translation regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Late spermatids: 4607.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035945, CAB037212, HPA056766" Approved Supported Vesicles NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 20 Vesicles "CAB037212: , HPA035945: , HPA056766: " "unprognostic (6.53e-3)" "unprognostic (1.66e-2)" "unprognostic (6.83e-2)" "unprognostic (2.85e-2)" "unprognostic (7.90e-3)" "unprognostic (7.73e-2)" "unprognostic (2.87e-1)" "unprognostic (5.01e-2)" "unprognostic (1.08e-2)" "unprognostic (1.74e-3)" "potential prognostic favorable (8.10e-8)" "unprognostic (8.63e-3)" "unprognostic (1.74e-1)" "unprognostic (2.73e-3)" "unprognostic (5.84e-2)" "unprognostic (3.45e-2)" "unprognostic (1.75e-1)" "unprognostic (1.96e-1)" "unprognostic (1.87e-1)" "unprognostic (1.10e-1)" "unprognostic (2.86e-2)" "unprognostic (1.32e-2)" "unprognostic (1.88e-2)" "unprognostic (9.43e-2)" "unprognostic (4.28e-2)" "unprognostic (3.15e-2)" "unprognostic (8.21e-2)" "unprognostic (1.07e-2)" "unprognostic (1.81e-1)" "unprognostic (6.60e-2)" "unprognostic (3.17e-2)" PAIP2B KIAA1155 ENSG00000124374 "Poly(A) binding protein interacting protein 2B" Q9ULR5 2 71182738-71227103 "Predicted intracellular proteins" "Translation regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 122.7" "Cell type enhanced" "Detected in many" "Breast lactating cells: 101.5;Esophageal apical cells: 117.7;Gastric chief cells: 127.8;Late primary spermatocytes: 158.9;Myonuclei: 102.0;Oocytes: 92.1;Pancreatic acinar cells: 320.0;Plasma cells: 98.2;Rod photoreceptor cells: 90.7;Salivary acinar cells: 136.7" "Cell type enhanced" "Detected in all" "oligodendrocyte: 46.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Stomach - Chief cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046784, HPA072371" Approved Approved Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 7: Liver cancer - Metabolism" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 5 Cytosol "HPA046784: , HPA072371: " "unprognostic (3.74e-1)" "unprognostic (7.22e-2)" "unprognostic (1.57e-1)" "unprognostic (2.90e-1)" "unprognostic (1.46e-1)" "unprognostic (4.32e-2)" "unprognostic (1.63e-1)" "unprognostic (9.25e-3)" "unprognostic (1.68e-1)" "unprognostic (9.59e-2)" "validated prognostic favorable (4.39e-12)" "validated prognostic favorable (1.55e-4)" "unprognostic (3.89e-2)" "unprognostic (1.48e-2)" "unprognostic (1.30e-1)" "unprognostic (6.72e-3)" "potential prognostic favorable (4.76e-5)" "unprognostic (4.49e-2)" "unprognostic (1.60e-2)" "unprognostic (1.20e-1)" "unprognostic (4.10e-3)" "unprognostic (5.24e-2)" "unprognostic (5.54e-2)" "unprognostic (1.54e-1)" "unprognostic (3.58e-2)" "unprognostic (1.65e-1)" "unprognostic (1.19e-1)" "unprognostic (1.66e-2)" "unprognostic (2.88e-1)" "unprognostic (1.46e-2)" "unprognostic (5.16e-2)" PAK1 ENSG00000149269 "P21 (RAC1) activated kinase 1" Q13153 11 77322017-77474635 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Exocytosis" "Allosteric enzyme, Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 118.6" "Cell type enhanced" "Detected in all" "Mast cells: 501.7;Neutrophils: 806.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 9 "classical monocyte: 182.4;eosinophil: 293.3;intermediate monocyte: 177.8;myeloid DC: 264.5;neutrophil: 433.6;non-classical monocyte: 203.7" "Group enriched" "Detected in all" 11 "dendritic cells: 264.5;granulocytes: 433.6;monocytes: 203.7" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Skeletal muscle - Skeletal myocytes, Skin - Outer root sheath cells, Stomach - Gastric mucous cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003565, CAB005312" Enhanced Supported Supported "Plasma membrane,Cytosol" NA NA 320000 "Cluster 7: Non-specific - Innate immune response" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 14: Neurons - Synaptic function" "Cluster 55: Lymphoma - Immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 80 "Plasma membrane, Cytosol" "CAB005312: , HPA003565: " "unprognostic (1.37e-1)" "unprognostic (6.91e-2)" "potential prognostic favorable (7.03e-4)" "unprognostic (2.40e-1)" "unprognostic (3.92e-2)" "unprognostic (2.59e-1)" "potential prognostic unfavorable (4.26e-4)" "unprognostic (1.35e-1)" "unprognostic (2.81e-1)" "unprognostic (3.79e-3)" "potential prognostic favorable (4.36e-6)" "unprognostic (3.34e-1)" "unprognostic (2.92e-1)" "unprognostic (8.46e-3)" "unprognostic (4.09e-2)" "unprognostic (4.40e-3)" "unprognostic (2.34e-3)" "unprognostic (6.30e-3)" "unprognostic (4.04e-3)" "unprognostic (3.25e-2)" "unprognostic (8.18e-2)" "unprognostic (5.66e-3)" "unprognostic (9.10e-2)" "unprognostic (1.52e-1)" "unprognostic (2.32e-3)" "unprognostic (9.11e-2)" "unprognostic (2.54e-1)" "unprognostic (3.38e-1)" "unprognostic (1.81e-1)" "unprognostic (2.20e-1)" "unprognostic (2.61e-2)" PAK1IP1 "bA421M1.5, FLJ20624, hPIP1, MAK11, PIP1, WDR84" ENSG00000111845 "PAK1 interacting protein 1" Q9NWT1 6 10694972-10709782 "Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 49.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030111, HPA030112" Supported Supported Nucleoli NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 74: Non-specific - Signal transduction" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 59 Nucleoli "HPA030111: , HPA030112: " "unprognostic (1.14e-1)" "unprognostic (3.28e-2)" "unprognostic (7.68e-2)" "unprognostic (1.26e-1)" "unprognostic (2.87e-1)" "unprognostic (2.26e-1)" "unprognostic (3.15e-1)" "unprognostic (1.11e-1)" "unprognostic (2.04e-2)" "potential prognostic unfavorable (2.32e-4)" "potential prognostic favorable (5.28e-4)" "unprognostic (1.37e-1)" "potential prognostic unfavorable (6.80e-5)" "validated prognostic unfavorable (6.64e-9)" "validated prognostic unfavorable (1.00e-5)" "unprognostic (7.78e-2)" "unprognostic (1.35e-3)" "unprognostic (8.67e-3)" "unprognostic (1.70e-2)" "unprognostic (3.31e-3)" "unprognostic (2.09e-1)" "unprognostic (1.82e-2)" "unprognostic (5.32e-2)" "unprognostic (7.21e-2)" "unprognostic (4.14e-2)" "unprognostic (4.80e-2)" "unprognostic (1.27e-3)" "unprognostic (2.45e-1)" "unprognostic (3.46e-1)" "unprognostic (4.89e-2)" "unprognostic (9.74e-2)" PAK2 "PAK65, PAKgamma" ENSG00000180370 "P21 (RAC1) activated kinase 2" Q13177 3 196739857-196832647 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Growth regulation, Host-virus interaction" "Allosteric enzyme, Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 826.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007794, HPA067552" Approved Supported "Nucleoplasm,Nuclear speckles,Focal adhesion sites,Cytosol" NA NA 1200000 "Cluster 21: Neutrophils - Unknown function" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 9: T-cells - Adaptive immunity: Regulation" 69 "Nucleoplasm, Nuclear speckles" "Focal adhesion sites, Cytosol" "CAB007794: , HPA067552: " "unprognostic (2.09e-1)" "unprognostic (1.92e-2)" "unprognostic (2.01e-1)" "unprognostic (1.30e-1)" "unprognostic (1.65e-1)" "unprognostic (1.07e-1)" "unprognostic (1.60e-1)" "unprognostic (1.51e-1)" "unprognostic (1.26e-1)" "potential prognostic unfavorable (1.15e-4)" "potential prognostic favorable (1.18e-4)" "unprognostic (7.01e-2)" "unprognostic (9.36e-3)" "unprognostic (3.37e-3)" "unprognostic (6.44e-3)" "potential prognostic unfavorable (3.05e-4)" "unprognostic (8.06e-3)" "unprognostic (8.97e-2)" "unprognostic (3.87e-1)" "unprognostic (1.05e-2)" "unprognostic (4.64e-3)" "unprognostic (3.43e-3)" "unprognostic (1.06e-1)" "unprognostic (2.49e-3)" "unprognostic (7.25e-2)" "unprognostic (9.00e-2)" "unprognostic (2.49e-1)" "unprognostic (1.39e-1)" "unprognostic (4.22e-2)" "unprognostic (2.22e-2)" "unprognostic (3.12e-1)" PAK3 "bPAK, hPAK3, MRX30, MRX47" ENSG00000077264 "P21 (RAC1) activated kinase 3" O75914 X 110944285-111227361 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Allosteric enzyme, Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.9;pancreas: 19.0;pituitary gland: 12.7" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 510.6;Brain excitatory neurons: 354.1;Brain inhibitory neurons: 417.8;Gonadotrophs: 414.2;Lacrimal acinar cells: 507.3;Lactotrophs: 1044.3;Other brain neurons: 583.3;Pancreatic islet cells: 827.2;Peritubular myoid cells: 497.8;Pituicytes/FSCs: 628.6;Sertoli cells: 877.4;Somatotrophs: 747.3;Thyrotrophs: 826.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "MAIT T-cell: 1.0" "Lineage enriched" "Detected in single" 5 "T-cells: 1.0" "Low cancer specificity" "Detected in many" "Prostate - Smooth muscle cells, Skeletal muscle - Fibroblasts, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044791, HPA060219" Approved Approved Vesicles NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 5 Vesicles "HPA044791: , HPA060219: " "unprognostic (1.60e-1)" "unprognostic (1.65e-1)" "potential prognostic favorable (1.46e-4)" "unprognostic (1.53e-1)" "unprognostic (1.87e-1)" "unprognostic (2.88e-2)" "unprognostic (1.17e-1)" "unprognostic (2.00e-1)" "unprognostic (2.07e-2)" "unprognostic (1.94e-1)" "unprognostic (1.26e-2)" "unprognostic (3.65e-2)" PAK4 ENSG00000130669 "P21 (RAC1) activated kinase 4" O96013 19 39125770-39182816 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025747, CAB044670, HPA070175, HPA072220" Uncertain Supported "Plasma membrane,Cell Junctions" NA Yes "Cluster 21: Neutrophils - Unknown function" "Cluster 72: Kidney - Transmembrane transport" "Cluster 19: Astrocytes - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 55 "Plasma membrane, Cell Junctions" "CAB025747: , CAB044670: , HPA070175: , HPA072220: " "unprognostic (2.08e-1)" "unprognostic (2.86e-2)" "unprognostic (1.37e-1)" "unprognostic (2.08e-2)" "unprognostic (1.28e-1)" "unprognostic (1.52e-1)" "unprognostic (2.53e-1)" "unprognostic (8.15e-2)" "unprognostic (6.93e-2)" "unprognostic (1.94e-1)" "unprognostic (2.66e-2)" "unprognostic (2.60e-1)" "unprognostic (6.01e-2)" "potential prognostic unfavorable (3.46e-4)" "unprognostic (7.84e-3)" "unprognostic (2.17e-3)" "unprognostic (1.15e-1)" "unprognostic (1.09e-2)" "unprognostic (1.70e-1)" "unprognostic (3.44e-2)" "unprognostic (2.39e-1)" "unprognostic (2.07e-1)" "potential prognostic unfavorable (4.10e-4)" "unprognostic (6.99e-3)" "unprognostic (4.35e-1)" "unprognostic (3.12e-1)" "unprognostic (1.55e-2)" "unprognostic (3.09e-1)" "unprognostic (3.11e-1)" "unprognostic (3.67e-2)" "unprognostic (1.95e-2)" PAK5 "KIAA1264, PAK7" ENSG00000101349 "P21 (RAC1) activated kinase 5" Q9P286 20 9537370-9839076 "Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 16.3;retina: 4.3" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 248.2;Brain inhibitory neurons: 236.2;Cone photoreceptor cells: 103.5;Corticotrophs: 265.5;Ependymal cells: 103.8;Gonadotrophs: 87.3;Oligodendrocyte progenitor cells: 93.7;Other brain neurons: 118.0;Retinal amacrine cells: 126.9;Retinal horizontal cells: 607.0" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Glioblastoma Multiforme (TCGA): 1.3;Kidney Chromophobe (TCGA): 2.0;Lung Squamous Cell Carcinoma (TCGA): 1.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Neuroblastoma: 2.4" "Colon - Colon enteroendocrine cells, Kidney - Intercalated cells, Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020444, HPA071060" Approved Supported "Nucleoplasm,Nuclear membrane,Mitochondria,Cytosol" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 2: Neurons - Nucleosome" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 41 Nucleoplasm "Nuclear membrane, Mitochondria, Cytosol" "HPA020444: , HPA071060: " "unprognostic (1.31e-1)" "potential prognostic favorable (6.03e-5)" "unprognostic (7.02e-2)" "unprognostic (1.25e-2)" "unprognostic (3.24e-2)" PAK6 PAK5 ENSG00000137843 "P21 (RAC1) activated kinase 6" Q9NQU5 15 40217428-40277487 "Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 31.0;esophagus: 24.5;skin 1: 26.9" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 21.3;Cytotrophoblasts: 67.8;Esophageal apical cells: 31.8;Esophageal basal cells: 33.9;Esophageal suprabasal cells: 42.9;Migrating cytotrophoblasts: 35.8;Suprabasal keratinocytes: 22.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary gland basal cells, Pituitary gland - Lactotropes, Skin - Keratinocyte (other), Stomach - Mitotic cells (Stomach), Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA031124 Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Cell Junctions" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 22 "Nucleoplasm, Nucleoli fibrillar center" "Cell Junctions" "HPA031124: " "unprognostic (1.83e-1)" "potential prognostic unfavorable (7.25e-5)" "unprognostic (7.77e-2)" "unprognostic (9.43e-3)" "unprognostic (2.85e-2)" "unprognostic (1.65e-1)" "unprognostic (1.46e-2)" "unprognostic (1.62e-1)" "unprognostic (4.72e-2)" "unprognostic (1.63e-1)" "unprognostic (4.67e-2)" "unprognostic (1.17e-1)" "potential prognostic unfavorable (1.13e-6)" "unprognostic (1.78e-1)" "unprognostic (7.95e-3)" "unprognostic (4.04e-1)" "unprognostic (2.36e-1)" "unprognostic (6.97e-2)" "unprognostic (4.11e-1)" "unprognostic (2.44e-2)" "unprognostic (1.58e-2)" "unprognostic (3.49e-2)" "unprognostic (2.99e-2)" "unprognostic (1.80e-1)" "unprognostic (1.21e-1)" "unprognostic (3.08e-2)" "unprognostic (2.12e-1)" "unprognostic (1.30e-1)" "unprognostic (5.41e-2)" PALB2 "FANCN, FLJ21816" ENSG00000083093 "Partner and localizer of BRCA2" Q86YC2 16 23603160-23641321 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes, Disease variant, Fanconi anemia, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 53.8;Early primary spermatocytes: 39.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB014895, HPA057000, HPA059851" Approved Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 64: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 79: Photoreceptor cells - Phototransduction" 37 "Nucleoplasm, Nuclear speckles" "CAB014895: , HPA057000: , HPA059851: " "unprognostic (2.64e-1)" "unprognostic (1.69e-1)" "unprognostic (5.51e-2)" "unprognostic (5.37e-3)" "unprognostic (2.50e-2)" "unprognostic (1.33e-1)" "unprognostic (2.24e-1)" "unprognostic (8.87e-3)" "unprognostic (3.39e-3)" "unprognostic (1.35e-3)" "potential prognostic unfavorable (5.57e-4)" "unprognostic (2.61e-1)" "unprognostic (3.70e-1)" "potential prognostic unfavorable (5.51e-4)" "unprognostic (5.87e-3)" "unprognostic (7.55e-2)" "unprognostic (7.10e-3)" "unprognostic (2.17e-1)" "unprognostic (2.27e-1)" "unprognostic (2.66e-2)" "unprognostic (6.07e-2)" "potential prognostic unfavorable (4.65e-4)" "unprognostic (9.18e-2)" "unprognostic (7.35e-2)" "unprognostic (2.24e-2)" "unprognostic (2.13e-1)" "unprognostic (3.35e-3)" "unprognostic (1.63e-1)" "unprognostic (1.74e-1)" "unprognostic (3.27e-1)" "unprognostic (6.63e-2)" PALD1 "KIAA1274, PALD" ENSG00000107719 "Phosphatase domain containing paladin 1" Q9ULE6 10 70478767-70668754 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Lymphatic endothelial cells: 176.8;Macrophages: 120.7;Microglia: 580.6;NK-cells: 247.1;pDCs: 170.8;Vascular endothelial cells: 66.0" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 714.2;pericyte: 398.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 2.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Liver - Vascular endothelial cells, Lung - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015696, HPA017343" Uncertain Supported Vesicles,Cytosol NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 17 "Vesicles, Cytosol" "HPA015696: , HPA017343: " "unprognostic (9.30e-2)" "unprognostic (2.34e-1)" "unprognostic (1.08e-1)" "unprognostic (3.22e-1)" "unprognostic (1.66e-2)" "unprognostic (1.97e-2)" "potential prognostic favorable (3.31e-4)" "unprognostic (1.16e-2)" "unprognostic (1.14e-1)" "unprognostic (1.89e-3)" "unprognostic (5.78e-2)" "unprognostic (2.19e-3)" "unprognostic (2.69e-3)" "unprognostic (8.37e-2)" "unprognostic (1.25e-1)" "unprognostic (4.15e-2)" "unprognostic (1.29e-1)" "unprognostic (2.76e-2)" "unprognostic (6.18e-2)" "unprognostic (1.08e-1)" "unprognostic (2.03e-1)" "unprognostic (1.37e-1)" "unprognostic (3.37e-1)" "unprognostic (5.78e-2)" "unprognostic (5.34e-2)" "unprognostic (1.33e-1)" "unprognostic (2.53e-1)" "unprognostic (2.51e-1)" "unprognostic (4.82e-3)" PALLD "CGI-151, KIAA0992, SIH002" ENSG00000129116 "Palladin, cytoskeletal associated protein" Q8WX93 4 168497052-168928457 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 2730.0;Medullary thymic epithelial cells: 940.9;Myonuclei: 2714.2;Salivary ionocytes: 885.2;Smooth muscle cells: 1507.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 13.9" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "testis cancer: 254.7" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Kidney - Fibroblasts, Prostate - Smooth muscle cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035905, CAB070159" Enhanced Supported "Plasma membrane,Actin filaments,Mitochondria,Cytosol" No No 12000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 14 "Actin filaments" "Plasma membrane, Mitochondria, Cytosol" "CAB070159: , HPA035905: " "unprognostic (2.18e-1)" "unprognostic (3.77e-2)" "unprognostic (2.47e-3)" "unprognostic (8.88e-2)" "unprognostic (1.92e-1)" "unprognostic (3.68e-2)" "unprognostic (4.45e-1)" "unprognostic (2.99e-3)" "unprognostic (1.91e-1)" "unprognostic (1.18e-2)" "potential prognostic favorable (6.17e-5)" "unprognostic (1.52e-1)" "unprognostic (1.25e-1)" "unprognostic (9.22e-2)" "unprognostic (1.02e-1)" "unprognostic (1.97e-2)" "unprognostic (4.21e-3)" "unprognostic (2.66e-2)" "unprognostic (4.37e-1)" "unprognostic (1.08e-2)" "unprognostic (8.86e-3)" "unprognostic (9.53e-2)" "unprognostic (2.40e-1)" "unprognostic (1.97e-1)" "unprognostic (4.67e-2)" "unprognostic (3.58e-1)" "unprognostic (1.79e-1)" "unprognostic (4.17e-2)" "unprognostic (1.61e-1)" "unprognostic (1.21e-2)" "unprognostic (3.60e-1)" PALM "KIAA0270, PALM1" ENSG00000099864 Paralemmin O75781 19 708935-748329 "Predicted intracellular proteins" "Cell shape" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 292.8" "Cell type enhanced" "Detected in many" "Astrocytes: 125.4;Bergmann glia: 64.4;Distal convoluted tubule cells: 65.0;Ependymal cells: 82.6;Fibro-adipogenic progenitors: 80.9;Gonadotrophs: 64.5;Leydig cells: 70.4;Lymphatic endothelial cells: 108.0;Müller glia: 97.6;Pituicytes/FSCs: 69.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "non-classical monocyte: 1.9" "Lineage enriched" "Detected in single" 19 "monocytes: 1.9" "Cancer enhanced" "Detected in many" "Neuroblastoma: 29.4" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Liver - Vascular endothelial cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041713, HPA049578" Approved Enhanced "Nucleoplasm,Plasma membrane" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 7 "Nucleoplasm, Plasma membrane" "HPA041713: , HPA049578: " "unprognostic (6.17e-3)" "unprognostic (5.73e-2)" "unprognostic (3.21e-1)" "unprognostic (1.25e-2)" "unprognostic (3.90e-2)" "unprognostic (6.92e-2)" "unprognostic (8.48e-2)" "unprognostic (2.12e-2)" "unprognostic (1.34e-2)" "unprognostic (1.06e-3)" "unprognostic (5.30e-3)" "unprognostic (3.85e-2)" "unprognostic (9.68e-2)" "unprognostic (1.70e-1)" "unprognostic (5.04e-2)" "unprognostic (1.30e-1)" "unprognostic (1.06e-1)" "unprognostic (2.93e-1)" "unprognostic (5.87e-2)" "unprognostic (1.82e-2)" "unprognostic (1.72e-1)" "unprognostic (1.24e-3)" "unprognostic (8.53e-2)" "unprognostic (2.30e-2)" "unprognostic (3.63e-2)" "unprognostic (9.07e-2)" "unprognostic (2.11e-2)" "unprognostic (4.48e-3)" "unprognostic (1.98e-1)" "unprognostic (3.74e-2)" "unprognostic (2.59e-2)" PALM2AKAP2 PALM2-AKAP2 ENSG00000157654 "PALM2 and AKAP2 fusion" "Q8IXS6, Q9Y2D5" 9 109498325-110172512 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 916.8;Alveolar cells type 1: 485.6;Ependymal cells: 455.4;Lymphatic endothelial cells: 404.0;Mast cells: 682.4;Oligodendrocytes: 987.2;Vascular endothelial cells: 648.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 10.7;naive B-cell: 10.3" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058905, HPA074153, HPA076866" Uncertain Supported "Plasma membrane" NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 5 "Plasma membrane" "HPA058905: , HPA074153: , HPA076866: " "unprognostic (1.47e-1)" "unprognostic (8.54e-2)" "potential prognostic unfavorable (1.88e-5)" "unprognostic (2.22e-1)" "unprognostic (2.25e-2)" "unprognostic (1.63e-1)" "unprognostic (6.42e-2)" "unprognostic (4.18e-2)" "validated prognostic favorable (3.03e-5)" "validated prognostic favorable (5.78e-5)" "potential prognostic unfavorable (7.73e-4)" "unprognostic (1.53e-1)" "unprognostic (3.83e-2)" "unprognostic (3.28e-2)" "unprognostic (7.13e-2)" "unprognostic (3.84e-3)" "unprognostic (2.77e-3)" "unprognostic (2.94e-2)" "unprognostic (4.11e-1)" "unprognostic (1.10e-1)" "unprognostic (1.43e-1)" "unprognostic (6.99e-3)" "unprognostic (8.08e-2)" "unprognostic (2.61e-2)" "unprognostic (1.82e-1)" "unprognostic (9.39e-2)" "unprognostic (3.44e-1)" PALM3 ENSG00000187867 "Paralemmin 3" A6NDB9 19 14053363-14062076 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 44.9;liver: 55.4;stomach 1: 29.4" "Group enriched" "Detected in some" 4 "Loop of henle epithelial cells: 21.3;Papillary tip epithelial cells: 17.7;Proximal tubule cells: 34.6;Renal collecting duct intercalated cells: 20.1;Renal collecting duct principal cells: 27.2;Renal connecting tubule cells: 30.9" "Cell type enhanced" "Detected in some" "lower rhombic lip: 3.8" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 27.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 19.8" "Breast - Breast glandular cells, Kidney - Macrophages, Minor Salivary Gland - Minor salivary gland ductal cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA052794, HPA056119" Enhanced Approved "Nucleoplasm,Nuclear bodies,Plasma membrane" NA NA 4400 "Cluster 70: Non-specific - Protein processing" "Cluster 49: Hindbrain - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 2 "Nucleoplasm, Nuclear bodies" "Plasma membrane" "HPA052794: , HPA056119: " "unprognostic (3.25e-2)" "unprognostic (1.32e-1)" "unprognostic (2.47e-2)" "unprognostic (4.83e-2)" "unprognostic (4.68e-2)" "unprognostic (1.89e-3)" "unprognostic (1.88e-1)" "unprognostic (7.61e-3)" "unprognostic (4.08e-1)" "unprognostic (1.39e-3)" "unprognostic (3.96e-2)" "potential prognostic favorable (5.56e-4)" "unprognostic (9.59e-2)" "unprognostic (2.02e-1)" "unprognostic (2.25e-1)" "unprognostic (2.62e-1)" "unprognostic (1.95e-2)" "unprognostic (4.77e-2)" "unprognostic (7.91e-2)" "unprognostic (6.44e-2)" "unprognostic (7.00e-2)" "unprognostic (4.02e-3)" "unprognostic (4.29e-2)" PALMD "C1orf11, FLJ20271, PALML" ENSG00000099260 Palmdelphin Q9NP74 1 99646113-99694541 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 122.7" "Cell type enhanced" "Detected in many" "Adipocytes: 662.7;Adrenal cortex cells: 333.3;Cardiomyocytes: 256.7;Choroid plexus epithelial cells: 390.0;Decidual stromal cells: 204.3;Lacrimal acinar cells: 471.0;Myonuclei: 461.6;Pituicytes/FSCs: 305.9;Salivary acinar cells: 318.4;Vascular endothelial cells: 425.5" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 346.2;endothelial cell: 593.9" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "choroid plexus: 85.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 28.5" "Adrenal gland - Adrenal cortex cells, Colon - Endothelial cells, Liver - Hepatocytes, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017959, HPA030549" Supported Supported "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 36: Choroid plexus - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 3 "Actin filaments" "Plasma membrane, Focal adhesion sites" "HPA017959: , HPA030549: " "unprognostic (6.72e-2)" "unprognostic (5.32e-2)" "unprognostic (3.52e-1)" "unprognostic (7.36e-2)" "unprognostic (4.02e-2)" "unprognostic (8.17e-2)" "unprognostic (2.38e-1)" "unprognostic (1.29e-1)" "unprognostic (8.85e-3)" "unprognostic (3.16e-1)" "potential prognostic favorable (2.25e-7)" "unprognostic (7.03e-3)" "unprognostic (2.00e-1)" "unprognostic (1.38e-2)" "potential prognostic favorable (5.33e-5)" "unprognostic (6.07e-2)" "unprognostic (8.48e-2)" "unprognostic (9.31e-2)" "unprognostic (1.63e-2)" "unprognostic (3.20e-1)" "unprognostic (1.87e-2)" "unprognostic (7.01e-2)" "unprognostic (2.27e-1)" "unprognostic (3.97e-2)" "unprognostic (7.86e-2)" "unprognostic (1.78e-1)" "unprognostic (1.84e-2)" "unprognostic (9.82e-3)" "unprognostic (5.26e-2)" "unprognostic (1.17e-1)" "unprognostic (2.32e-2)" PALS1 "FLJ12615, MPP5" ENSG00000072415 "Protein associated with LIN7 1, MAGUK p55 family member" Q8N3R9 14 67240713-67336061 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epicardial cells: 329.8;Podocytes: 637.0" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 268.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000993, HPA063890" Enhanced Approved "Nucleoplasm,Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 51: Secretory epithelial cells - Mixed function" 47 "Nucleoplasm, Plasma membrane" "Cell Junctions, Cytosol" "HPA000993: , HPA063890: " "unprognostic (4.20e-3)" "unprognostic (3.35e-1)" "unprognostic (3.60e-1)" "unprognostic (6.94e-3)" "unprognostic (3.01e-2)" "unprognostic (4.52e-2)" "unprognostic (1.19e-1)" "unprognostic (2.73e-1)" "unprognostic (5.81e-2)" "unprognostic (2.08e-2)" "potential prognostic favorable (5.80e-10)" "unprognostic (4.46e-3)" "unprognostic (1.75e-1)" "unprognostic (7.61e-3)" "unprognostic (8.89e-2)" "unprognostic (2.96e-2)" "unprognostic (2.04e-1)" "unprognostic (1.74e-1)" "unprognostic (1.98e-1)" "unprognostic (5.46e-2)" "potential prognostic unfavorable (9.08e-5)" "unprognostic (7.09e-3)" "unprognostic (1.69e-3)" "unprognostic (6.51e-2)" "unprognostic (3.13e-2)" "unprognostic (9.46e-3)" "unprognostic (3.64e-1)" "unprognostic (1.93e-1)" "unprognostic (3.12e-1)" "unprognostic (1.15e-1)" "unprognostic (3.63e-1)" PALS2 "MPP6, p55T, VAM-1" ENSG00000105926 "Protein associated with LIN7 2, MAGUK p55 family member" Q9NZW5 7 24573268-24694193 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 17.9;testis: 23.3" "Cell type enhanced" "Detected in many" "Bergmann glia: 677.8;Cone photoreceptor cells: 188.4;Pancreatic islet cells: 208.8" "Cell type enhanced" "Detected in all" "Bergmann glia: 763.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 8.3" "Group enriched" "Detected in many" 5 "B-cells: 8.3;dendritic cells: 2.9;T-cells: 2.3" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Minor Salivary Gland - Endothelial cells, Spleen - B-cells (Spleen), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019085, HPA020456" Enhanced NA NA "Cluster 24: Non-specific - Transcription" "Cluster 67: Testis - Mixed function" "Cluster 29: Forebrain - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" 17 "HPA019085: , HPA020456: " "unprognostic (4.67e-3)" "unprognostic (2.01e-2)" "unprognostic (1.92e-1)" "unprognostic (8.02e-3)" "unprognostic (8.02e-3)" "unprognostic (1.45e-1)" "unprognostic (5.34e-3)" "unprognostic (2.08e-3)" "unprognostic (2.89e-3)" "unprognostic (2.60e-3)" "potential prognostic favorable (3.67e-8)" "unprognostic (6.29e-3)" "unprognostic (3.00e-1)" "unprognostic (4.60e-3)" "unprognostic (1.11e-3)" "unprognostic (1.51e-3)" "unprognostic (7.92e-3)" "unprognostic (2.04e-1)" "unprognostic (2.01e-2)" "unprognostic (1.58e-1)" "unprognostic (2.64e-2)" "unprognostic (4.28e-1)" "unprognostic (6.74e-3)" "unprognostic (1.62e-1)" "unprognostic (1.24e-3)" "unprognostic (1.36e-1)" "unprognostic (1.43e-1)" "unprognostic (3.01e-1)" "unprognostic (3.50e-1)" "unprognostic (1.70e-3)" "unprognostic (3.02e-1)" PAM "PAL, PHM" ENSG00000145730 "Peptidylglycine alpha-amidating monooxygenase" P19021 5 102753981-103029730 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Lipid metabolism" "Lyase, Monooxygenase, Multifunctional enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 691.0;heart muscle: 1159.0" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 905.1;Myonuclei: 1098.5;Neuroendocrine cells: 1549.3;Pituicytes/FSCs: 1164.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells, Breast - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026119, HPA042260" Enhanced Approved "Golgi apparatus,Cytosol" "Secreted in other tissues" Enzyme NA NA 31000000 "Cluster 1: T-cells - Unknown function" "Cluster 35: Non-specific - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" 2 "Golgi apparatus, Cytosol" "CAB026119: , HPA042260: " "unprognostic (7.19e-2)" "unprognostic (2.69e-2)" "unprognostic (1.79e-2)" "unprognostic (1.46e-1)" "unprognostic (1.08e-1)" "unprognostic (2.12e-1)" "unprognostic (1.98e-1)" "unprognostic (2.95e-3)" "unprognostic (2.79e-2)" "unprognostic (1.76e-1)" "potential prognostic favorable (3.37e-6)" "unprognostic (2.18e-1)" "unprognostic (1.40e-1)" "unprognostic (1.58e-3)" "unprognostic (1.52e-1)" "unprognostic (1.12e-1)" "unprognostic (1.98e-2)" "unprognostic (3.37e-2)" "unprognostic (1.12e-2)" "unprognostic (1.88e-1)" "unprognostic (2.57e-2)" "unprognostic (2.80e-2)" "unprognostic (1.11e-1)" "unprognostic (3.91e-1)" "unprognostic (1.11e-1)" "unprognostic (1.60e-2)" "unprognostic (1.67e-1)" "unprognostic (8.17e-2)" "unprognostic (6.13e-2)" "unprognostic (9.35e-2)" "unprognostic (4.28e-1)" PAM16 "Magmas, Tim16, TIMM16" ENSG00000217930 "Presequence translocase associated motor 16" Q9Y3D7 16 4331549-4355607 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Protein transport, Translocation, Transport" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 120.4" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 23.6;Brain inhibitory neurons: 23.8;Choroid plexus epithelial cells: 17.5;Ependymal cells: 20.5;Gastric chief cells: 21.8;Microglia: 19.6;Oligodendrocytes: 28.2;Oocytes: 23.0;Other brain neurons: 29.7;Parietal cells: 31.8;Renal collecting duct principal cells: 16.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062721 Approved Nucleoplasm,Microtubules,Mitochondria NA NA "Cluster 18: Non-specific - Translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 33: Neurons - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 98: Neurons - Neurotransmission & signaling" 12 "Nucleoplasm, Mitochondria" Microtubules "HPA062721: " "unprognostic (1.07e-2)" "unprognostic (2.44e-1)" "unprognostic (2.90e-2)" "unprognostic (1.12e-1)" "unprognostic (4.38e-1)" "unprognostic (3.66e-1)" "unprognostic (1.16e-2)" "unprognostic (6.42e-3)" "unprognostic (6.92e-2)" "potential prognostic unfavorable (1.71e-5)" "unprognostic (1.30e-3)" "unprognostic (1.46e-2)" "unprognostic (9.08e-2)" "unprognostic (9.99e-2)" "unprognostic (7.41e-2)" "unprognostic (9.26e-2)" "unprognostic (1.27e-1)" "unprognostic (6.15e-3)" "unprognostic (1.89e-1)" "unprognostic (4.33e-2)" "unprognostic (1.51e-1)" "unprognostic (3.27e-3)" "unprognostic (9.92e-2)" "unprognostic (5.27e-3)" "unprognostic (2.54e-2)" "unprognostic (1.18e-1)" "unprognostic (1.03e-1)" "unprognostic (2.49e-1)" "unprognostic (8.07e-2)" "unprognostic (4.35e-2)" PAMR1 "DKFZP586H2123, RAMP" ENSG00000149090 "Peptidase domain containing associated with muscle regeneration 1" Q6UXH9 11 35431823-35530300 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Serine protease homolog" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 276.6;Astrocytes: 636.4;Breast myoepithelial cells: 209.2;Decidual stromal cells: 84.7;Endometrial stromal cells: 128.8;Ependymal cells: 666.9;Fibro-adipogenic progenitors: 143.5;Fibroblasts: 119.5;Gonadotrophs: 86.6;Salivary myoepithelial cells: 142.5;Thymic myoid cells: 87.0" "Group enriched" "Detected in many" 5 "astrocyte: 737.2;ependymal cell: 747.5;fibroblast: 235.6" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 26.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 11.3;testis cancer: 13.1" "Breast - Breast myoepithelial cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Minor Salivary Gland - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted - unknown location" Other NA NA 2700000 "Cluster 75: Ovary - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 28: Astrocytes - Homeostasis & neuron support" "unprognostic (7.95e-2)" "unprognostic (2.78e-1)" "unprognostic (1.70e-1)" "unprognostic (1.60e-1)" "unprognostic (3.54e-1)" "unprognostic (2.96e-2)" "unprognostic (3.14e-3)" "unprognostic (1.73e-3)" "unprognostic (1.49e-1)" "unprognostic (2.62e-1)" "unprognostic (1.37e-2)" "unprognostic (7.80e-3)" "unprognostic (1.87e-3)" "unprognostic (8.39e-2)" "unprognostic (3.15e-2)" "unprognostic (3.06e-2)" "unprognostic (2.23e-1)" "unprognostic (2.94e-1)" "unprognostic (1.47e-2)" "unprognostic (5.46e-2)" "unprognostic (3.46e-2)" "unprognostic (3.42e-2)" "unprognostic (1.03e-1)" "unprognostic (5.68e-2)" "unprognostic (1.61e-2)" "unprognostic (2.94e-2)" "potential prognostic unfavorable (3.35e-4)" "unprognostic (2.56e-1)" "unprognostic (1.93e-1)" "unprognostic (1.52e-1)" PAN2 "hPAN2, KIAA0710, USP52" ENSG00000135473 "Poly(A) specific ribonuclease subunit PAN2" Q504Q3 12 56316223-56334053 "Enzymes, Predicted intracellular proteins" "mRNA processing" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 39: Testis - Nuclear processes" "Cluster 6: Non-specific - Immune response" "Cluster 38: Non-specific - Transcription" "Cluster 18: Adrenal cortex cells - Steroidogensis" 15 "unprognostic (3.23e-1)" "unprognostic (3.00e-2)" "unprognostic (5.24e-2)" "unprognostic (6.65e-2)" "unprognostic (2.33e-1)" "unprognostic (8.03e-2)" "unprognostic (3.40e-1)" "unprognostic (9.14e-2)" "unprognostic (3.58e-2)" "unprognostic (6.07e-2)" "validated prognostic favorable (1.81e-4)" "validated prognostic favorable (6.54e-4)" "unprognostic (2.15e-1)" "unprognostic (2.05e-1)" "unprognostic (8.11e-2)" "unprognostic (1.73e-2)" "unprognostic (6.00e-2)" "unprognostic (9.49e-2)" "unprognostic (3.38e-2)" "unprognostic (1.23e-1)" "unprognostic (1.07e-1)" "unprognostic (9.15e-2)" "unprognostic (1.14e-2)" "unprognostic (1.35e-1)" "unprognostic (2.20e-2)" "potential prognostic favorable (1.51e-4)" "unprognostic (5.14e-3)" "unprognostic (1.57e-1)" "unprognostic (2.14e-1)" "unprognostic (1.10e-1)" "unprognostic (3.96e-2)" PAN3 ENSG00000152520 "Poly(A) specific ribonuclease subunit PAN3" Q58A45 13 28138506-28295335 "Enzymes, Predicted intracellular proteins" "mRNA processing" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 1436.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028817 Approved NA NA "Cluster 32: Basophils - Transcription" "Cluster 49: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 6: Leukemia - Signal transduction" "Cluster 24: Neutrophils - Innate immunity signal integration" 20 "HPA028817: " "unprognostic (2.01e-2)" "unprognostic (1.64e-1)" "unprognostic (1.65e-1)" "unprognostic (1.36e-2)" "unprognostic (1.56e-2)" "unprognostic (7.66e-2)" "unprognostic (9.37e-2)" "unprognostic (9.57e-2)" "unprognostic (2.82e-2)" "unprognostic (2.36e-1)" "unprognostic (4.56e-2)" "unprognostic (3.18e-2)" "unprognostic (1.21e-2)" "unprognostic (2.85e-2)" "unprognostic (1.51e-1)" "unprognostic (4.11e-2)" "unprognostic (3.34e-2)" "unprognostic (5.81e-2)" "unprognostic (2.93e-1)" "unprognostic (1.29e-2)" "unprognostic (3.19e-2)" "unprognostic (1.00e-1)" "unprognostic (1.46e-2)" "unprognostic (5.79e-2)" "unprognostic (3.82e-1)" "unprognostic (1.76e-2)" "unprognostic (5.42e-3)" "unprognostic (3.01e-2)" "unprognostic (1.03e-1)" "unprognostic (6.49e-2)" "unprognostic (9.57e-2)" PANK1 "MGC24596, PANK, PANK1a, PANK1b" ENSG00000152782 "Pantothenate kinase 1" Q8TE04 10 89582988-89645242 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Coenzyme A biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 42.5;liver: 103.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 95.7;Choroid plexus epithelial cells: 126.6;Distal convoluted tubule cells: 61.7;Hepatocytes: 251.4;Myonuclei: 131.1;Proximal tubule cells: 96.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 16: Liver & Kidney - Metabolism" "Cluster 5: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 88: Proximal tubular cells - Transmembrane transport" "unprognostic (1.39e-1)" "unprognostic (7.80e-2)" "unprognostic (1.45e-1)" "unprognostic (9.02e-2)" "unprognostic (3.88e-2)" "unprognostic (5.59e-2)" "unprognostic (1.81e-1)" "potential prognostic favorable (2.05e-4)" "unprognostic (1.27e-1)" "unprognostic (2.31e-2)" "potential prognostic favorable (3.44e-12)" "unprognostic (7.00e-3)" "potential prognostic favorable (9.95e-4)" "potential prognostic favorable (5.11e-5)" "unprognostic (9.11e-2)" "unprognostic (1.40e-1)" "unprognostic (5.19e-2)" "unprognostic (2.34e-1)" "unprognostic (6.66e-2)" "unprognostic (2.13e-1)" "unprognostic (1.06e-1)" "unprognostic (3.22e-3)" "unprognostic (4.52e-2)" "unprognostic (2.77e-1)" "unprognostic (1.10e-3)" "unprognostic (8.00e-2)" "unprognostic (5.53e-3)" "unprognostic (1.43e-1)" "unprognostic (1.70e-1)" "unprognostic (2.46e-2)" "unprognostic (9.84e-2)" PANK2 "C20orf48, FLJ11729, HARP, HSS, NBIA1, PKAN" ENSG00000125779 "Pantothenate kinase 2" Q9BZ23 20 3888839-3929887 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Angiogenesis, Coenzyme A biosynthesis" "Kinase, Transferase" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 428.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008440 Approved Supported Cytosol NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 38: Sub-cortical - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 24: Neutrophils - Innate immunity signal integration" 15 Cytosol "HPA008440: " "unprognostic (1.88e-1)" "unprognostic (8.86e-3)" "unprognostic (4.17e-3)" "unprognostic (5.67e-2)" "unprognostic (4.07e-1)" "unprognostic (2.52e-1)" "unprognostic (3.38e-1)" "unprognostic (2.13e-2)" "unprognostic (3.36e-1)" "unprognostic (1.19e-2)" "potential prognostic favorable (4.15e-5)" "unprognostic (3.25e-2)" "unprognostic (1.02e-1)" "potential prognostic unfavorable (1.71e-6)" "unprognostic (3.11e-3)" "unprognostic (1.23e-1)" "unprognostic (1.62e-1)" "unprognostic (2.86e-2)" "potential prognostic unfavorable (9.70e-4)" "unprognostic (7.90e-2)" "unprognostic (3.52e-1)" "unprognostic (1.85e-1)" "unprognostic (1.18e-2)" "unprognostic (2.06e-1)" "unprognostic (3.22e-1)" "unprognostic (1.58e-2)" "unprognostic (1.36e-2)" "unprognostic (6.56e-2)" "unprognostic (6.54e-2)" "unprognostic (5.51e-2)" "unprognostic (1.45e-1)" PANK3 FLJ12899 ENSG00000120137 "Pantothenate kinase 3" Q9H999 5 168548495-168579368 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Coenzyme A biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 202.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078669 Approved Approved "Golgi apparatus" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 77: Intestine - Digestion" "Cluster 35: Non-specific - DNA binding" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 1 "Golgi apparatus" "HPA078669: " "unprognostic (3.47e-3)" "unprognostic (3.10e-2)" "unprognostic (8.76e-2)" "unprognostic (9.45e-3)" "unprognostic (1.49e-2)" "unprognostic (4.87e-2)" "unprognostic (8.04e-2)" "unprognostic (3.01e-2)" "unprognostic (2.22e-2)" "unprognostic (1.01e-2)" "potential prognostic favorable (1.79e-5)" "unprognostic (1.35e-3)" "unprognostic (1.41e-2)" "unprognostic (4.18e-2)" "unprognostic (4.01e-1)" "unprognostic (5.48e-2)" "unprognostic (2.38e-1)" "unprognostic (2.47e-1)" "unprognostic (5.06e-2)" "unprognostic (2.86e-2)" "potential prognostic unfavorable (1.09e-4)" "unprognostic (4.55e-2)" "unprognostic (1.20e-1)" "unprognostic (6.60e-2)" "unprognostic (5.71e-3)" "unprognostic (3.23e-2)" "unprognostic (2.41e-1)" "unprognostic (1.57e-1)" "unprognostic (1.92e-1)" "unprognostic (1.21e-2)" "unprognostic (4.99e-2)" PANK4 FLJ10782 ENSG00000157881 "Pantothenate kinase 4 (inactive)" Q9NVE7 1 2508537-2526597 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Coenzyme A biosynthesis" Hydrolase Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 7.1;Bergmann glia: 6.9;Brain excitatory neurons: 7.9;Brain inhibitory neurons: 8.7;Distal convoluted tubule cells: 5.4;Ependymal cells: 3.7;Loop of henle epithelial cells: 4.3;Microglia: 4.7;Oligodendrocyte progenitor cells: 6.7;Oligodendrocytes: 5.4;Other brain neurons: 5.9;Renal collecting duct intercalated cells: 5.6;Renal connecting tubule cells: 4.3;Retinal pigment epithelial cells: 4.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebral cortex: 3.7" "Immune cell enhanced" "Detected in single" "eosinophil: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011723, HPA012036, HPA027961" Uncertain Approved Cytosol NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 23: Choroid plexus - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 98: Neurons - Neurotransmission & signaling" 12 Cytosol "HPA011723: , HPA012036: , HPA027961: " "unprognostic (8.14e-2)" "unprognostic (1.24e-2)" "unprognostic (1.36e-1)" "unprognostic (2.64e-1)" "unprognostic (3.59e-1)" "unprognostic (5.00e-2)" "potential prognostic favorable (6.72e-4)" "unprognostic (9.18e-3)" "unprognostic (4.44e-2)" "unprognostic (3.90e-2)" "unprognostic (2.26e-2)" "unprognostic (7.72e-2)" "unprognostic (3.83e-2)" "unprognostic (6.49e-2)" "unprognostic (7.29e-2)" "unprognostic (2.57e-1)" "unprognostic (8.23e-2)" "unprognostic (1.49e-3)" "unprognostic (5.62e-3)" "unprognostic (8.56e-2)" "unprognostic (3.10e-2)" "unprognostic (5.51e-2)" "unprognostic (1.35e-1)" "unprognostic (1.39e-1)" "unprognostic (5.54e-2)" "unprognostic (1.20e-1)" "potential prognostic favorable (3.05e-4)" "unprognostic (1.17e-1)" PANO1 PANO ENSG00000288675 "Proapoptotic nucleolar protein 1" I0J062 11 797511-799190 "Predicted intracellular proteins" Apoptosis "Tumor suppressor" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 3.4" "Cell type enhanced" "Detected in many" "Early spermatids: 16.0;Hepatic stellate cells: 6.5;Lactotrophs: 4.9;Retinal bipolar cells: 5.9;Retinal horizontal cells: 8.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" NA NA "Cluster 70: Non-specific - Protein processing" "Cluster 15: Non-specific - Transcription" "Cluster 54: Non-specific - Transcription" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" "potential prognostic unfavorable (1.84e-4)" "unprognostic (1.55e-2)" "unprognostic (2.03e-2)" "unprognostic (2.29e-1)" "unprognostic (8.17e-2)" "unprognostic (1.80e-1)" "unprognostic (1.01e-2)" "potential prognostic favorable (4.13e-5)" "unprognostic (2.92e-2)" "unprognostic (8.80e-2)" "unprognostic (2.61e-1)" "unprognostic (3.47e-2)" "unprognostic (2.22e-1)" "unprognostic (1.79e-1)" PANX1 "MRS1, PX1, UNQ2529" ENSG00000110218 "Pannexin 1" Q96RD7 11 94128841-94181968 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Calcium transport, Differentiation, Ion transport, Oogenesis, Transport" "Calcium channel, Ion channel" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 129.4;Platelets: 88.8;Suprabasal keratinocytes: 77.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016930 Uncertain Enhanced "Plasma membrane" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 75: Ovary - Mixed function" "Cluster 14: Neurons - Synaptic function" "Cluster 24: Non-specific - Unknown function" "Cluster 103: Non-specific - Basic cellular processes" 21 "Plasma membrane" "HPA016930: " "unprognostic (7.40e-3)" "potential prognostic unfavorable (5.48e-4)" "unprognostic (3.77e-2)" "unprognostic (6.18e-3)" "unprognostic (5.24e-2)" "unprognostic (3.15e-1)" "unprognostic (1.82e-1)" "unprognostic (8.61e-3)" "unprognostic (4.72e-2)" "unprognostic (7.59e-2)" "potential prognostic favorable (2.96e-4)" "unprognostic (2.18e-2)" "unprognostic (7.39e-3)" "unprognostic (2.60e-2)" "unprognostic (2.36e-1)" "potential prognostic unfavorable (2.09e-4)" "unprognostic (1.66e-3)" "unprognostic (1.66e-2)" "unprognostic (1.32e-1)" "unprognostic (3.97e-2)" "unprognostic (8.29e-3)" "unprognostic (2.64e-3)" "unprognostic (7.14e-2)" "unprognostic (1.45e-1)" "unprognostic (7.82e-3)" "unprognostic (8.11e-2)" "unprognostic (1.70e-1)" "unprognostic (2.45e-2)" "unprognostic (2.70e-1)" "unprognostic (2.49e-2)" "unprognostic (3.68e-2)" PANX2 "hPANX2, PX2" ENSG00000073150 "Pannexin 2" Q96RD6 22 50170731-50180295 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 39.0" "Cell type enhanced" "Detected in many" "Bergmann glia: 43.1;Brain excitatory neurons: 35.9;Brain inhibitory neurons: 27.2;Corticotrophs: 23.6;Esophageal apical cells: 23.6;Lactotrophs: 37.0;Neutrophils: 32.4;Other brain neurons: 37.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 2.0" "Lineage enhanced" "Detected in single" "granulocytes: 2.0" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Spleen - Neutrophils_2, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004624, HPA039117" Enhanced Supported "Plasma membrane" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 27: Cerebellum - Synaptic function" "Cluster 24: Neurons - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 98: Neurons - Neurotransmission & signaling" "Plasma membrane" "HPA004624: , HPA039117: " "unprognostic (1.30e-1)" "unprognostic (3.66e-2)" "unprognostic (2.97e-1)" "unprognostic (4.67e-2)" "unprognostic (7.46e-3)" "unprognostic (2.90e-2)" "unprognostic (1.60e-2)" "unprognostic (3.71e-1)" "potential prognostic unfavorable (9.15e-5)" "potential prognostic unfavorable (7.90e-5)" "unprognostic (5.42e-2)" "unprognostic (7.80e-2)" "unprognostic (1.35e-1)" "unprognostic (7.87e-3)" "unprognostic (3.66e-1)" "unprognostic (7.46e-2)" "unprognostic (1.08e-1)" "unprognostic (3.66e-1)" "unprognostic (2.64e-1)" "unprognostic (1.59e-3)" "unprognostic (8.36e-3)" "unprognostic (2.80e-2)" "unprognostic (1.94e-1)" "unprognostic (1.06e-1)" "unprognostic (1.43e-1)" "potential prognostic unfavorable (2.99e-4)" PANX3 Px3 ENSG00000154143 "Pannexin 3" Q96QZ0 11 124611428-124620356 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Other brain neurons: 4.0;Undifferentiated spermatogonia: 1.4" "Cell type enhanced" "Detected in single" "thalamic excitatory: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Gallbladder cancer: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 72: Neuronal - Signal transduction" "Cluster 109: Neurons - Neuronal signaling" PAOX PAO ENSG00000148832 "Polyamine oxidase" Q6QHF9 10 133379261-133391694 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 27.4" "Group enriched" "Detected in some" 7 "Distal convoluted tubule cells: 3.1;Late spermatids: 3.9;Loop of henle epithelial cells: 5.1;Papillary tip epithelial cells: 7.5;Podocytes: 3.6;Proximal tubule cells: 7.8;Renal collecting duct intercalated cells: 5.7;Renal collecting duct principal cells: 9.6;Renal connecting tubule cells: 4.4;Tuft cells: 11.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Spleen - Macrophages, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047782 Uncertain Nucleoplasm,Centrosome NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 30: White matter - Myelination" "Cluster 55: Lymphoma - Immune response" "Cluster 105: Non-specific - Mixed function" Centrosome Nucleoplasm "HPA047782: " "unprognostic (3.30e-2)" "unprognostic (1.55e-2)" "unprognostic (6.17e-2)" "unprognostic (1.30e-2)" "unprognostic (9.68e-2)" "unprognostic (3.14e-1)" "unprognostic (3.87e-3)" "unprognostic (3.52e-3)" "unprognostic (3.54e-3)" "unprognostic (3.22e-2)" "unprognostic (2.03e-3)" "unprognostic (1.34e-1)" "unprognostic (2.22e-1)" "unprognostic (7.32e-3)" "potential prognostic favorable (1.46e-4)" "unprognostic (4.92e-2)" "unprognostic (4.08e-2)" "unprognostic (3.54e-1)" "unprognostic (2.84e-1)" "unprognostic (6.51e-3)" "unprognostic (3.69e-1)" "unprognostic (5.62e-2)" "unprognostic (3.34e-1)" "unprognostic (1.68e-2)" "unprognostic (5.60e-2)" "unprognostic (4.56e-1)" "unprognostic (1.31e-1)" PAPLN MGC50452 ENSG00000100767 "Papilin, proteoglycan like sulfated glycoprotein" O95428 14 73237497-73274640 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 168.0;Bergmann glia: 59.1;Decidual stromal cells: 61.9;Endometrial stromal cells: 71.4;Fibro-adipogenic progenitors: 57.5;Leydig cells: 86.5;Müller glia: 94.4;Peritubular myoid cells: 119.5;Pituicytes/FSCs: 118.2;Proximal tubule cells: 223.8" "Cell type enhanced" "Detected in many" "astrocyte: 159.3;Bergmann glia: 62.2;fibroblast: 84.5" "Cancer enhanced" "Detected in all" "Kidney Renal Papillary Cell Carcinoma (TCGA): 52.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "neutrophil: 2.5;plasmacytoid DC: 5.5" "Group enriched" "Detected in many" 7 "dendritic cells: 5.5;granulocytes: 2.5" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Breast - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA048682 Uncertain "Secreted - unknown location" "Enzyme inhibitor" NA NA 13000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 72: Kidney - Transmembrane transport" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 88: Proximal tubular cells - Transmembrane transport" "HPA048682: " "unprognostic (4.26e-2)" "unprognostic (3.12e-3)" "unprognostic (1.76e-2)" "unprognostic (2.85e-1)" "unprognostic (6.76e-2)" "unprognostic (5.62e-2)" "unprognostic (2.13e-1)" "unprognostic (8.81e-2)" "unprognostic (2.64e-3)" "unprognostic (1.51e-1)" "unprognostic (1.03e-1)" "unprognostic (1.58e-1)" "unprognostic (3.10e-3)" "unprognostic (2.07e-2)" "unprognostic (4.98e-2)" "unprognostic (1.11e-3)" "unprognostic (5.74e-2)" "unprognostic (8.09e-2)" "unprognostic (2.06e-1)" "unprognostic (3.58e-2)" "unprognostic (6.04e-2)" "unprognostic (2.46e-1)" "unprognostic (9.57e-2)" "unprognostic (1.89e-1)" "unprognostic (4.38e-1)" "unprognostic (3.40e-2)" "unprognostic (3.42e-2)" "unprognostic (3.45e-2)" "unprognostic (4.38e-2)" "unprognostic (2.24e-2)" "unprognostic (4.97e-2)" PAPOLA PAP ENSG00000090060 "Poly(A) polymerase alpha" P51003 14 96501433-96567116 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 1282.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001788 Supported Supported Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 4 Nucleoplasm "HPA001788: " "unprognostic (5.94e-2)" "unprognostic (7.23e-2)" "unprognostic (3.86e-2)" "unprognostic (2.50e-2)" "unprognostic (1.93e-1)" "unprognostic (2.94e-1)" "unprognostic (1.69e-1)" "unprognostic (2.33e-1)" "unprognostic (2.66e-2)" "unprognostic (4.59e-2)" "potential prognostic favorable (8.61e-4)" "unprognostic (1.41e-2)" "unprognostic (2.39e-2)" "potential prognostic unfavorable (9.97e-4)" "unprognostic (1.54e-2)" "unprognostic (2.06e-1)" "unprognostic (3.21e-1)" "unprognostic (9.49e-2)" "unprognostic (1.44e-1)" "unprognostic (5.04e-1)" "potential prognostic unfavorable (7.64e-5)" "unprognostic (6.93e-2)" "unprognostic (1.74e-2)" "unprognostic (1.26e-2)" "unprognostic (3.23e-1)" "unprognostic (2.64e-1)" "unprognostic (4.63e-2)" "unprognostic (1.76e-2)" "unprognostic (1.95e-1)" "unprognostic (4.15e-3)" "unprognostic (2.87e-1)" PAPOLB PAPT ENSG00000218823 "Poly(A) polymerase beta" Q9NRJ5 7 4857738-4862030 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 101 "testis: 27.9" "Cell type enhanced" "Detected in single" "Late primary spermatocytes: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" HPA047285 Approved Nucleoplasm NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 35: Non-specific - DNA binding" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" Nucleoplasm "HPA047285: " PAPOLG FLJ12972 ENSG00000115421 "Poly(A) polymerase gamma" Q9BWT3 2 60756253-60802086 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017795, HPA035349, HPA035350" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" No No "Cluster 35: Neutrophils - Protein binding" "Cluster 61: Non-specific - Transcription" "Cluster 9: Non-specific - Receptor signaling" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 9: T-cells - Adaptive immunity: Regulation" 6 Nucleoplasm "Nuclear bodies, Cytosol" "CAB017795: , HPA035349: , HPA035350: " "unprognostic (1.78e-2)" "unprognostic (1.29e-1)" "unprognostic (2.37e-1)" "unprognostic (1.29e-1)" "unprognostic (2.88e-3)" "unprognostic (1.13e-2)" "unprognostic (4.96e-1)" "unprognostic (7.27e-2)" "unprognostic (3.86e-2)" "unprognostic (3.40e-2)" "unprognostic (1.71e-2)" "unprognostic (1.76e-1)" "unprognostic (2.85e-2)" "unprognostic (7.18e-2)" "unprognostic (2.78e-1)" "unprognostic (1.87e-1)" "potential prognostic favorable (6.84e-4)" "unprognostic (5.55e-3)" "unprognostic (1.56e-1)" "unprognostic (1.04e-1)" "unprognostic (1.95e-3)" "unprognostic (1.13e-1)" "unprognostic (3.39e-2)" "unprognostic (1.96e-1)" "unprognostic (1.83e-1)" "unprognostic (2.69e-1)" "unprognostic (1.75e-1)" "unprognostic (1.00e-1)" "unprognostic (9.05e-2)" PAPPA "ASBABP2, DIPLA1, IGFBP-4ase, PAPA, PAPP-A, PAPPA1" ENSG00000182752 "Pappalysin 1" Q13219 9 116153791-116402321 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "placenta: 68.1" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 226.2;Endometrial stromal cells: 334.0;Epicardial cells: 218.3;Fibro-adipogenic progenitors: 121.2;Fibroblasts: 165.8;Medullary thymic epithelial cells: 127.2;Mesothelial cells: 263.3;Renal collecting duct principal cells: 731.4;Renal connecting tubule cells: 357.6;Retinal amacrine cells: 216.2" "Cell type enhanced" "Detected in many" "mammillary body: 129.9" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 6.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 33.8" "Colon - Enteric glia cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA001667, CAB016724" Enhanced "Secreted in female reproductive system" Enzyme NA NA 100000000 "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 108: Fibroblasts - ECM organization" 3 "CAB016724: , HPA001667: " "unprognostic (1.32e-1)" "unprognostic (2.20e-1)" "unprognostic (1.30e-1)" "potential prognostic unfavorable (8.51e-4)" "unprognostic (1.47e-1)" "unprognostic (4.10e-2)" "unprognostic (1.48e-2)" "unprognostic (2.58e-1)" "unprognostic (4.28e-2)" "potential prognostic unfavorable (2.66e-4)" "unprognostic (1.05e-1)" "unprognostic (6.34e-3)" "unprognostic (1.05e-1)" "unprognostic (4.23e-2)" "unprognostic (3.89e-3)" PAPPA2 "PAPP-A2, PAPPE, PLAC3" ENSG00000116183 "Pappalysin 2" Q9BXP8 1 176463171-176845601 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "placenta: 53.4" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 305.9;Extravillous trophoblasts: 267.3;Loop of henle epithelial cells: 348.5;Neuroendocrine cells: 256.6;Pancreatic islet cells: 312.5;Retinal amacrine cells: 100.8;Somatotrophs: 121.3;Syncytiotrophoblasts: 232.3" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Kidney Chromophobe (TCGA): 9.8;Kidney Renal Papillary Cell Carcinoma (TCGA): 5.7;Pancreatic Adenocarcinoma (TCGA): 2.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pituitary gland - Somatotropes, Testis - Spermatogonia, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in some" "Region enhanced" "Detected in some" "cerebellum: 8.1" "HPA018412, HPA018430" Enhanced Approved "Endoplasmic reticulum,Vesicles" "Secreted in female reproductive system" Enzyme NA NA 1900000 "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" "Endoplasmic reticulum, Vesicles" "HPA018412: , HPA018430: " "unprognostic (2.43e-2)" "unprognostic (1.30e-1)" "unprognostic (5.75e-2)" "unprognostic (1.32e-1)" "potential prognostic unfavorable (1.13e-4)" "unprognostic (3.65e-1)" "unprognostic (2.91e-1)" "unprognostic (1.24e-2)" "unprognostic (2.53e-1)" "unprognostic (3.21e-2)" PAPSS1 "ATPSK1, PAPSS" ENSG00000138801 "3'-phosphoadenosine 5'-phosphosulfate synthase 1" O43252 4 107590276-107720234 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Multifunctional enzyme, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial glandular cells: 943.6;Endometrial luminal cells: 388.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "basophil: 322.6;eosinophil: 360.6" "Lineage enriched" "Detected in all" 6 "granulocytes: 360.6" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049781 Approved Approved "Nucleoplasm,Nucleoli rim,Mitotic chromosome" Yes No 9600 "Cluster 41: Basophils - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 5: Rhabdoid - Unknown function" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 2 "Nucleoli rim, Mitotic chromosome" Nucleoplasm "HPA049781: " "unprognostic (1.97e-2)" "unprognostic (9.44e-2)" "unprognostic (1.27e-2)" "unprognostic (1.85e-1)" "unprognostic (1.10e-2)" "unprognostic (3.60e-2)" "unprognostic (5.48e-2)" "unprognostic (9.90e-2)" "unprognostic (1.75e-1)" "unprognostic (7.19e-3)" "potential prognostic favorable (8.10e-5)" "unprognostic (6.87e-3)" "unprognostic (2.18e-2)" "potential prognostic unfavorable (2.45e-7)" "unprognostic (4.02e-2)" "unprognostic (1.79e-1)" "unprognostic (1.51e-2)" "unprognostic (3.02e-1)" "unprognostic (2.30e-1)" "unprognostic (6.73e-2)" "unprognostic (1.19e-2)" "unprognostic (1.57e-1)" "unprognostic (2.23e-1)" "unprognostic (2.93e-1)" "unprognostic (1.70e-1)" "unprognostic (2.61e-2)" "unprognostic (2.23e-1)" "unprognostic (1.31e-1)" "unprognostic (9.25e-2)" "unprognostic (2.25e-2)" "unprognostic (6.58e-2)" PAPSS2 ATPSK2 ENSG00000198682 "3'-phosphoadenosine 5'-phosphosulfate synthase 2" O95340 10 87659613-87747705 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Multifunctional enzyme, Nucleotidyltransferase, Transferase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 132.1" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 1065.3;Alveolar cells type 1: 595.0;cDC: 427.1;Colonocytes: 344.5;Enterocytes: 471.6;Hepatocytes: 293.4;Kupffer cells: 260.3;Macrophages: 360.3;monocytes: 493.4;Pancreatic islet cells: 508.5" "Cell type enhanced" "Detected in many" "endothelial cell: 317.7;pericyte: 366.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 4.0;myeloid DC: 2.1;non-classical monocyte: 7.7" "Group enriched" "Detected in many" 7 "dendritic cells: 2.1;monocytes: 7.7" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Heart muscle - Endothelial cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Fibroblasts, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA071224, HPA075267" Enhanced Approved Mitochondria No No 9800 "Cluster 40: Monocytes - Innate immune response" "Cluster 28: Liver & Adrenal gland - Secretion" "Cluster 47: Endothelial cells - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 7 Mitochondria "HPA071224: , HPA075267: " "unprognostic (1.62e-1)" "unprognostic (9.66e-3)" "unprognostic (2.85e-1)" "unprognostic (1.94e-2)" "unprognostic (6.57e-2)" "unprognostic (2.09e-2)" "unprognostic (1.08e-1)" "unprognostic (1.52e-1)" "unprognostic (2.58e-2)" "unprognostic (8.82e-2)" "unprognostic (1.28e-2)" "unprognostic (5.19e-2)" "unprognostic (4.66e-2)" "unprognostic (1.19e-2)" "unprognostic (3.98e-1)" "unprognostic (9.32e-3)" "unprognostic (8.03e-3)" "unprognostic (1.71e-2)" "unprognostic (3.79e-1)" "unprognostic (4.53e-2)" "unprognostic (2.62e-2)" "unprognostic (8.39e-3)" "unprognostic (9.19e-2)" "unprognostic (1.20e-1)" "unprognostic (1.94e-1)" "unprognostic (4.68e-3)" "potential prognostic unfavorable (2.85e-5)" "unprognostic (2.39e-3)" "unprognostic (3.11e-1)" "potential prognostic unfavorable (6.10e-5)" "unprognostic (7.58e-3)" PAQR3 ENSG00000163291 "Progestin and adipoQ receptor family member 3" Q6TCH7 4 78887127-78939438 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 171.8;Early spermatids: 130.7;Late spermatids: 231.4;Mast cells: 139.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 3.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 68: Non-specific - Basic cellular processes" "Cluster 2: Neurons - Nucleosome" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 6 "unprognostic (2.27e-1)" "unprognostic (1.25e-1)" "unprognostic (6.42e-2)" "unprognostic (5.08e-2)" "unprognostic (3.83e-2)" "unprognostic (4.89e-2)" "unprognostic (9.74e-2)" PAQR4 FLJ30002 ENSG00000162073 "Progestin and adipoQ receptor family member 4" Q8N4S7 16 2969270-2973484 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 144.1;retina: 59.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 49.7;Esophageal apical cells: 41.9;Oligodendrocytes: 61.0;Respiratory deuterosomal cells: 105.7;Respiratory secretory cells: 43.0;Retinal pigment epithelial cells: 85.3;Rod photoreceptor cells: 73.5;Tuft cells: 92.2" "Cell type enhanced" "Detected in all" "oligodendrocyte: 81.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "non-classical monocyte: 3.6" "Lineage enriched" "Detected in single" 9 "monocytes: 3.6" "Low cancer specificity" "Detected in all" "Kidney - Macrophages, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Skeletal muscle - Skeletal myocytes, Stomach - Mitotic cells (Stomach), Testis - Spermatogonia" "Low region specificity" "Detected in all" HPA068394 Approved Vesicles NA Yes "Cluster 40: Monocytes - Innate immune response" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 54: Non-specific - Transcription" "Cluster 79: Photoreceptor cells - Phototransduction" 2 Vesicles "HPA068394: " "unprognostic (5.04e-2)" "unprognostic (3.74e-1)" "unprognostic (3.87e-1)" "unprognostic (7.53e-2)" "unprognostic (3.56e-2)" "unprognostic (1.15e-2)" "unprognostic (9.89e-2)" "unprognostic (1.65e-1)" "unprognostic (2.38e-3)" "unprognostic (1.27e-2)" "validated prognostic unfavorable (3.43e-4)" "validated prognostic unfavorable (6.72e-5)" "potential prognostic unfavorable (7.60e-5)" "unprognostic (2.29e-3)" "potential prognostic unfavorable (7.77e-5)" "unprognostic (1.06e-2)" "unprognostic (2.42e-3)" "unprognostic (2.57e-1)" "unprognostic (7.57e-2)" "unprognostic (1.57e-2)" "unprognostic (1.57e-1)" "unprognostic (4.03e-2)" "unprognostic (7.23e-2)" "unprognostic (8.40e-2)" "unprognostic (7.07e-2)" "unprognostic (4.52e-1)" "unprognostic (2.47e-1)" "potential prognostic favorable (4.43e-4)" "unprognostic (2.58e-1)" "unprognostic (4.47e-2)" "unprognostic (3.15e-2)" PAQR5 "FLJ20190, MPRG" ENSG00000137819 "Progestin and adipoQ receptor family member 5" Q9NXK6 15 69298912-69407780 "Predicted membrane proteins" "Differentiation, Oogenesis" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 49.3" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 95.8;Distal convoluted tubule cells: 292.7;Esophageal apical cells: 83.0;Esophageal suprabasal cells: 80.5;Late spermatids: 226.3;Loop of henle epithelial cells: 208.1;Mast cells: 84.7;Pancreatic duct cells: 98.3;Proximal tubule cells: 136.7;Renal collecting duct intercalated cells: 196.3;Renal collecting duct principal cells: 80.2;Renal connecting tubule cells: 374.2" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 73.2;endothelial cell: 178.5;fibroblast: 49.7" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 32.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Cholangiocytes, Stomach - Parietal cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076729 Approved Vesicles NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 7: Liver cancer - Metabolism" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 6 Vesicles "HPA076729: " "unprognostic (7.49e-2)" "unprognostic (1.66e-2)" "unprognostic (2.18e-2)" "unprognostic (1.08e-1)" "unprognostic (9.71e-2)" "unprognostic (2.16e-2)" "unprognostic (4.22e-2)" "unprognostic (1.08e-1)" "unprognostic (4.28e-2)" "unprognostic (8.79e-2)" "validated prognostic favorable (1.88e-13)" "validated prognostic favorable (5.72e-5)" "unprognostic (1.55e-2)" "unprognostic (5.84e-3)" "unprognostic (7.32e-2)" "unprognostic (1.47e-2)" "unprognostic (2.02e-3)" "unprognostic (1.13e-2)" "unprognostic (2.96e-1)" "unprognostic (1.13e-1)" "validated prognostic unfavorable (3.93e-5)" "validated prognostic unfavorable (3.79e-4)" "unprognostic (7.96e-2)" "unprognostic (2.07e-1)" "unprognostic (1.48e-2)" "unprognostic (8.16e-2)" "unprognostic (3.49e-1)" "unprognostic (6.91e-2)" PAQR6 "FLJ22672, PRdelta" ENSG00000160781 "Progestin and adipoQ receptor family member 6" Q6TCH4 1 156243320-156248117 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 20 "brain: 911.8" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 21.3;Astrocytes: 55.9;Bergmann glia: 49.7;Ependymal cells: 22.3;Epicardial cells: 15.9;Müller glia: 52.6;Oligodendrocytes: 64.5;Schwann cells: 24.9" "Cell type enhanced" "Detected in all" "astrocyte: 59.6;Bergmann glia: 56.5;oligodendrocyte: 96.1" "Cancer enriched" "Detected in many" 4 "Glioblastoma Multiforme (TCGA): 32.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "NK-cell: 5.7" "Lineage enriched" "Detected in single" 7 "NK-cells: 5.7" "Cancer enhanced" "Detected in all" "Myeloma: 27.1" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA No "Cluster 15: NK-cells - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 11: Muller glia cells - Retinal homeostasis" 4 "unprognostic (5.36e-2)" "unprognostic (2.13e-1)" "unprognostic (6.57e-2)" "unprognostic (2.03e-1)" "potential prognostic unfavorable (4.97e-4)" "unprognostic (3.34e-2)" "unprognostic (1.23e-1)" "unprognostic (1.28e-1)" "unprognostic (5.45e-2)" "potential prognostic unfavorable (9.51e-7)" "unprognostic (1.82e-2)" "unprognostic (8.27e-2)" "unprognostic (4.02e-1)" "unprognostic (2.68e-2)" "unprognostic (2.22e-1)" "unprognostic (2.21e-1)" "unprognostic (1.80e-2)" "unprognostic (1.13e-1)" "unprognostic (1.54e-1)" "unprognostic (1.37e-2)" "unprognostic (1.83e-2)" "unprognostic (6.12e-3)" "unprognostic (5.21e-3)" "unprognostic (5.67e-2)" "unprognostic (1.96e-1)" "unprognostic (3.02e-1)" "unprognostic (2.00e-2)" "unprognostic (1.38e-1)" "unprognostic (3.20e-2)" "unprognostic (3.12e-1)" PAQR7 "MPRA, mSR, PGLP" ENSG00000182749 "Progestin and adipoQ receptor family member 7" Q86WK9 1 25861484-25875708 "Predicted membrane proteins" "Differentiation, Oogenesis" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 60.1" "Cell type enriched" "Detected in many" 7 "Late spermatids: 3371.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046936 Approved Approved Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 5 Cytosol "HPA046936: " "unprognostic (2.36e-1)" "unprognostic (5.78e-2)" "unprognostic (2.52e-1)" "unprognostic (7.60e-2)" "unprognostic (8.65e-2)" "unprognostic (5.15e-3)" "unprognostic (3.44e-1)" "unprognostic (4.14e-1)" "unprognostic (1.99e-1)" "unprognostic (1.07e-1)" "potential prognostic favorable (1.23e-6)" "unprognostic (1.65e-2)" "unprognostic (1.28e-3)" "potential prognostic unfavorable (1.12e-4)" "unprognostic (5.80e-2)" "unprognostic (1.63e-2)" "unprognostic (1.80e-1)" "unprognostic (1.13e-1)" "unprognostic (1.48e-1)" "unprognostic (2.58e-2)" "unprognostic (3.33e-1)" "unprognostic (6.00e-2)" "unprognostic (2.68e-1)" "unprognostic (2.51e-1)" "unprognostic (1.86e-1)" "unprognostic (1.45e-2)" "unprognostic (8.87e-3)" "unprognostic (1.31e-2)" "unprognostic (1.39e-2)" "unprognostic (3.07e-1)" "unprognostic (8.01e-2)" PAQR8 "C6orf33, LMPB1, MPRB" ENSG00000170915 "Progestin and adipoQ receptor family member 8" Q8TEZ7 6 52361421-52407777 "Predicted membrane proteins, Transporters" "Differentiation, Oogenesis" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 138.7" "Cell type enhanced" "Detected in some" "Enterocytes: 2.0;Foveolar cells: 1.6;Medullary thymic epithelial cells: 2.4;Oligodendrocytes: 1.1" "Cell type enhanced" "Detected in some" "Bergmann glia: 1.5;oligodendrocyte: 1.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "testis cancer: 31.6" "Prostate - Smooth muscle cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064625 Supported "Golgi apparatus,Plasma membrane" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 1: Enterocytes - Absorption and Digestion" 3 "Plasma membrane" "Golgi apparatus" "HPA064625: " "unprognostic (2.08e-1)" "unprognostic (1.62e-2)" "unprognostic (4.27e-2)" "unprognostic (7.25e-2)" "unprognostic (1.05e-2)" "unprognostic (6.76e-2)" "unprognostic (2.94e-1)" "unprognostic (2.20e-1)" "unprognostic (4.50e-3)" "unprognostic (6.79e-3)" "unprognostic (1.81e-2)" "unprognostic (1.78e-2)" "unprognostic (7.54e-2)" "unprognostic (2.16e-2)" "unprognostic (6.16e-2)" "unprognostic (1.49e-1)" "unprognostic (4.14e-2)" "unprognostic (1.90e-2)" "unprognostic (1.07e-1)" "unprognostic (2.26e-2)" "unprognostic (1.73e-1)" "unprognostic (3.78e-1)" "unprognostic (5.32e-3)" "unprognostic (1.37e-1)" "unprognostic (1.45e-2)" "unprognostic (2.08e-2)" "unprognostic (1.61e-1)" "unprognostic (1.00e-1)" "unprognostic (1.98e-1)" "unprognostic (7.37e-2)" "unprognostic (3.21e-1)" PAQR9 "BLNC1, FLJ41938" ENSG00000188582 "Progestin and adipoQ receptor family member 9" Q6ZVX9 3 142949164-142963674 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "liver: 9.6;retina: 8.9;testis: 11.2" "Cell type enhanced" "Detected in some" "Brain inhibitory neurons: 14.3;Corticotrophs: 20.9;Early spermatids: 39.3;Erythrocyte progenitors: 20.2;Hepatocytes: 27.8;Late primary spermatocytes: 27.9;Late spermatids: 150.0;Syncytiotrophoblasts: 65.2" "Cell type enhanced" "Detected in many" "midbrain-derived inhibitory: 42.6" "Cancer enriched" "Detected in single" 11 "Liver Hepatocellular Carcinoma (TCGA): 7.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "liver cancer: 2.2" "Heart muscle - Cardiomyocytes, Pituitary gland - Corticotropes, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Spleen - Erythrocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA052798 Uncertain NA NA "Cluster 47: Testis - Mixed function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 47: Leukemia - Hemostasis" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 2 "HPA052798: " "unprognostic (2.62e-1)" "unprognostic (1.33e-2)" "potential prognostic unfavorable (2.31e-6)" PARD3 "ASIP, Baz, Bazooka, PAR3, PARD3A, PPP1R118" ENSG00000148498 "Par-3 family cell polarity regulator" Q8TEW0 10 34109560-34815325 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 2031.3;Podocytes: 2848.1" "Cell type enhanced" "Detected in all" "pericyte: 2229.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 50 "basophil: 9.6" "Lineage enriched" "Detected in single" 96 "granulocytes: 9.6" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 1, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030443 Approved Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 54: Non-specific - Ribosome" "Cluster 46: Brainstem - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 51: Secretory epithelial cells - Mixed function" 74 "Plasma membrane, Cell Junctions" "HPA030443: " "unprognostic (2.87e-2)" "unprognostic (5.92e-3)" "unprognostic (2.50e-1)" "unprognostic (2.35e-1)" "unprognostic (8.35e-2)" "unprognostic (4.63e-2)" "unprognostic (1.74e-2)" "potential prognostic favorable (2.23e-6)" "unprognostic (1.20e-1)" "unprognostic (5.70e-3)" "potential prognostic favorable (9.59e-4)" "unprognostic (2.33e-2)" "unprognostic (2.31e-2)" "validated prognostic unfavorable (1.07e-4)" "validated prognostic unfavorable (8.27e-4)" "unprognostic (1.08e-1)" "unprognostic (1.45e-3)" "unprognostic (1.32e-1)" "unprognostic (3.28e-2)" "potential prognostic unfavorable (1.22e-4)" "unprognostic (2.65e-2)" "unprognostic (1.41e-3)" "unprognostic (2.29e-2)" "unprognostic (1.66e-1)" "unprognostic (1.07e-2)" "unprognostic (2.36e-1)" "unprognostic (3.45e-1)" "unprognostic (5.04e-2)" "unprognostic (2.18e-1)" "unprognostic (1.51e-2)" "unprognostic (2.92e-1)" PARD3B "ALS2CR19, PAR3beta, Par3L" ENSG00000116117 "Par-3 family cell polarity regulator beta" Q8TEW8 2 204545475-205620162 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ependymal cells: 2108.7;Podocytes: 4928.4" "Cell type enhanced" "Detected in all" "ependymal cell: 2249.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Breast - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblasts_1, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035283 Approved Supported "Cell Junctions" NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 46: Brainstem - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 57: Podocytes - Glomerular filtration" 10 "Cell Junctions" "HPA035283: " "unprognostic (1.77e-3)" "unprognostic (4.85e-2)" "unprognostic (1.00e-1)" "unprognostic (2.01e-1)" "unprognostic (4.85e-2)" "unprognostic (4.97e-2)" "unprognostic (2.42e-2)" "unprognostic (1.79e-2)" "unprognostic (1.77e-1)" "unprognostic (8.06e-2)" "validated prognostic favorable (1.51e-9)" "validated prognostic favorable (2.29e-4)" "unprognostic (8.01e-2)" "unprognostic (1.68e-1)" "unprognostic (4.29e-2)" "unprognostic (2.67e-3)" "unprognostic (2.95e-1)" "unprognostic (6.67e-2)" "unprognostic (2.54e-1)" "unprognostic (2.06e-1)" "unprognostic (3.11e-2)" "unprognostic (2.42e-1)" "unprognostic (1.09e-1)" "unprognostic (7.28e-2)" "unprognostic (1.28e-2)" "unprognostic (3.14e-2)" "unprognostic (2.34e-1)" "unprognostic (1.63e-1)" "unprognostic (1.09e-1)" "unprognostic (1.83e-2)" "unprognostic (3.89e-1)" PARD6A "PAR-6, PAR-6A, PAR6alpha, TAX40, TIP-40" ENSG00000102981 "Par-6 family cell polarity regulator alpha" Q9NPB6 16 67660946-67662774 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 45.1;testis: 41.3" "Cell type enriched" "Detected in many" 9 "Late spermatids: 487.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009733, HPA041551" Approved Approved "Plasma membrane,Cell Junctions,Actin filaments,Cytosol" No No "Cluster 43: Non-specific - Transcription & Translation" "Cluster 70: Non-specific - Protein processing" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 30 "Actin filaments" "Plasma membrane, Cell Junctions, Cytosol" "CAB009733: , HPA041551: " "unprognostic (1.37e-2)" "unprognostic (6.03e-3)" "unprognostic (2.14e-2)" "unprognostic (1.68e-1)" "unprognostic (1.92e-2)" "unprognostic (1.13e-1)" "unprognostic (6.88e-2)" "unprognostic (1.60e-2)" "unprognostic (4.76e-3)" "unprognostic (9.84e-2)" "unprognostic (9.24e-3)" "unprognostic (1.27e-2)" "unprognostic (5.35e-3)" "unprognostic (1.67e-3)" "unprognostic (1.89e-2)" "unprognostic (2.14e-1)" "unprognostic (9.85e-2)" "unprognostic (5.59e-2)" "unprognostic (1.64e-1)" "unprognostic (8.89e-2)" "unprognostic (2.27e-1)" "potential prognostic favorable (7.34e-5)" "unprognostic (1.65e-1)" "unprognostic (5.69e-2)" "unprognostic (1.02e-2)" "unprognostic (2.72e-2)" "unprognostic (1.80e-1)" "unprognostic (1.24e-2)" "unprognostic (1.74e-1)" "unprognostic (2.51e-2)" "unprognostic (3.63e-2)" PARD6B PAR-6B ENSG00000124171 "Par-6 family cell polarity regulator beta" Q9BYG5 20 50731580-50756795 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 15.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 285.9;Endometrial glandular cells: 426.3;Ocular epithelial cells: 298.5;Urothelial cells: 311.1" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 91.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Breast - Breast glandular cells, Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013376, HPA013708" Uncertain Supported "Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 72: Kidney - Transmembrane transport" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 27: Breast cancer - Unknown function" "Cluster 51: Secretory epithelial cells - Mixed function" 57 "Cell Junctions, Cytosol" "Plasma membrane" "HPA013376: , HPA013708: " "unprognostic (1.92e-2)" "unprognostic (2.10e-1)" "unprognostic (8.80e-2)" "unprognostic (1.70e-1)" "unprognostic (8.35e-2)" "unprognostic (4.57e-1)" "unprognostic (1.21e-1)" "unprognostic (7.62e-2)" "unprognostic (1.03e-1)" "unprognostic (3.17e-2)" "potential prognostic favorable (9.33e-5)" "unprognostic (1.18e-1)" "unprognostic (4.73e-2)" "potential prognostic unfavorable (1.44e-4)" "unprognostic (1.21e-2)" "unprognostic (2.31e-1)" "unprognostic (6.48e-2)" "unprognostic (7.40e-2)" "unprognostic (3.68e-3)" "unprognostic (2.09e-2)" "unprognostic (1.35e-1)" "unprognostic (2.14e-3)" "unprognostic (3.09e-2)" "unprognostic (2.83e-2)" "unprognostic (5.55e-2)" "unprognostic (8.31e-3)" "unprognostic (2.59e-1)" "unprognostic (1.60e-2)" "unprognostic (3.73e-1)" "unprognostic (4.61e-2)" "unprognostic (1.28e-3)" PARD6G "PAR-6G, PAR6gamma" ENSG00000178184 "Par-6 family cell polarity regulator gamma" Q9BYG4 18 80157232-80247514 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 35.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 89.8;Esophageal apical cells: 66.1;Esophageal suprabasal cells: 77.8;Lymphatic endothelial cells: 258.7;Podocytes: 333.5;Suprabasal keratinocytes: 114.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Skin - Keratinocyte (other), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA047017 Uncertain Approved "Plasma membrane" NA NA "Cluster 58: Skin - Keratinization" "Cluster 29: Forebrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 25 "Plasma membrane" "HPA047017: " "unprognostic (1.77e-1)" "unprognostic (1.46e-2)" "unprognostic (1.40e-1)" "unprognostic (3.15e-1)" "unprognostic (1.37e-1)" "unprognostic (9.28e-2)" "unprognostic (1.51e-1)" "unprognostic (1.17e-1)" "unprognostic (1.57e-2)" "unprognostic (1.90e-2)" "potential prognostic favorable (8.31e-6)" "unprognostic (2.16e-3)" "unprognostic (1.55e-1)" "unprognostic (1.71e-2)" "unprognostic (3.75e-2)" "unprognostic (1.57e-1)" "unprognostic (1.02e-2)" "unprognostic (7.55e-2)" "unprognostic (9.77e-2)" "unprognostic (3.81e-2)" "unprognostic (1.92e-1)" "unprognostic (1.82e-2)" "unprognostic (3.99e-2)" "unprognostic (9.56e-3)" "unprognostic (1.02e-1)" "unprognostic (2.51e-1)" "unprognostic (8.57e-2)" "unprognostic (2.66e-1)" "unprognostic (1.78e-1)" "unprognostic (1.73e-1)" "unprognostic (9.72e-3)" PARG ENSG00000227345 "Poly(ADP-ribose) glycohydrolase" Q86W56 10 49818279-49970203 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 416.7;Epicardial cells: 363.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021819, HPA041247, HPA053007" Enhanced Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 16: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 1 Nucleoplasm "Nuclear bodies, Cytosol" "HPA021819: , HPA041247: , HPA053007: " "unprognostic (1.09e-1)" "unprognostic (5.89e-3)" "unprognostic (3.11e-2)" "unprognostic (2.47e-1)" "unprognostic (1.66e-1)" "unprognostic (2.58e-1)" "unprognostic (3.21e-2)" "potential prognostic favorable (1.87e-7)" "unprognostic (2.15e-1)" "unprognostic (1.68e-1)" "potential prognostic favorable (4.76e-4)" "unprognostic (3.02e-1)" "unprognostic (3.30e-1)" "potential prognostic unfavorable (9.52e-5)" "unprognostic (3.21e-2)" "unprognostic (3.46e-2)" "unprognostic (8.65e-2)" "unprognostic (1.21e-1)" "unprognostic (1.91e-1)" "unprognostic (1.11e-1)" "unprognostic (9.48e-2)" "unprognostic (9.06e-2)" "unprognostic (9.20e-3)" "unprognostic (2.94e-2)" "unprognostic (3.09e-2)" "unprognostic (3.07e-1)" "unprognostic (2.66e-1)" "unprognostic (2.08e-1)" "unprognostic (2.53e-1)" "unprognostic (1.28e-2)" "unprognostic (1.25e-1)" PARK7 "DJ-1, DJ1, GATD2" ENSG00000116288 "Parkinsonism associated deglycase" Q99497 1 7954291-7985505 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Autophagy, DNA damage, DNA repair, Fertilization, Inflammatory response, Stress response" "Chaperone, Hydrolase, Protease, RNA-binding" "Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Platelets: 982.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004190, CAB005870" Supported Supported "Nucleoplasm,Cytosol,Flagellar centriole,Mid piece" NA NA 28000000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 37: Non-specific - mRNA processing" "Cluster 11: Muller glia cells - Retinal homeostasis" 78 "Nucleoplasm, Cytosol" "Flagellar centriole, Mid piece" "CAB005870: , HPA004190: " "unprognostic (3.42e-2)" "unprognostic (1.90e-1)" "unprognostic (3.44e-3)" "unprognostic (3.25e-3)" "unprognostic (1.86e-2)" "unprognostic (1.64e-1)" "unprognostic (2.54e-2)" "unprognostic (2.28e-1)" "unprognostic (3.73e-3)" "potential prognostic unfavorable (2.25e-5)" "unprognostic (2.98e-3)" "unprognostic (9.71e-2)" "potential prognostic favorable (9.00e-4)" "unprognostic (4.40e-2)" "potential prognostic unfavorable (1.77e-4)" "unprognostic (1.53e-1)" "unprognostic (3.40e-2)" "unprognostic (4.72e-1)" "unprognostic (2.05e-1)" "unprognostic (1.71e-1)" "unprognostic (1.39e-1)" "unprognostic (5.96e-2)" "unprognostic (2.51e-1)" "unprognostic (3.10e-1)" "unprognostic (1.25e-1)" "potential prognostic favorable (1.05e-4)" "unprognostic (6.62e-2)" "unprognostic (8.07e-2)" "unprognostic (4.82e-2)" "unprognostic (2.14e-2)" "unprognostic (5.61e-3)" PARL "PRO2207, PSARL, PSARL1, RHBDS1" ENSG00000175193 "Presenilin associated rhomboid like" Q9H300 3 183829271-183884933 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 78.0;Microglia: 79.3;Oocytes: 142.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019545 Approved Supported Mitochondria NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 22: Non-specific - Basic cellular functions" 5 Mitochondria "HPA019545: " "unprognostic (1.18e-1)" "unprognostic (2.11e-1)" "unprognostic (4.10e-2)" "unprognostic (1.12e-3)" "unprognostic (2.04e-1)" "unprognostic (1.98e-2)" "unprognostic (1.63e-1)" "unprognostic (5.67e-2)" "unprognostic (2.20e-2)" "unprognostic (6.86e-2)" "unprognostic (1.70e-3)" "unprognostic (1.32e-2)" "unprognostic (8.49e-2)" "potential prognostic unfavorable (4.80e-4)" "unprognostic (8.20e-3)" "unprognostic (4.13e-3)" "potential prognostic unfavorable (3.40e-4)" "potential prognostic favorable (7.63e-4)" "unprognostic (6.78e-2)" "unprognostic (6.82e-3)" "unprognostic (1.13e-1)" "unprognostic (5.87e-2)" "unprognostic (1.13e-1)" "unprognostic (6.86e-2)" "unprognostic (4.47e-1)" "unprognostic (4.90e-2)" "unprognostic (2.19e-2)" "unprognostic (2.80e-3)" "unprognostic (2.27e-1)" "unprognostic (2.63e-1)" "unprognostic (4.00e-2)" PARM1 "Cipar1, DKFZP564O0823, WSC4" ENSG00000169116 "Prostate androgen-regulated mucin-like protein 1" Q6UWI2 4 74933095-75050115 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 223.4;Alveolar cells type 2: 323.4;Colonocytes: 341.9;Goblet cells: 196.6;Gonadotrophs: 179.6;Pericytes: 187.7;Pituicytes/FSCs: 202.2;Retinal pigment epithelial cells: 230.2;Somatotrophs: 187.6;Thyrotrophs: 247.7;Transitional alveolar cells: 181.5;Vascular smooth muscle cells: 190.5" "Cell type enhanced" "Detected in many" "vascular associated smooth muscle cell: 151.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 15 "memory B-cell: 8.1;myeloid DC: 4.0;naive B-cell: 5.6" "Group enriched" "Detected in many" 16 "B-cells: 8.1;dendritic cells: 4.0" "Cancer enhanced" "Detected in many" "Myeloma: 39.2" "Adipose visceral - Endothelial cells, Adrenal gland - Fibroblasts, Breast - Endothelial cells, Heart muscle - Cardiomyocytes, Kidney - Fibroblasts, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Smooth muscle cells, Skin - Outer root sheath cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038236 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 55: Lymphoma - Immune response" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 1 "Nucleoplasm, Vesicles, Cytosol" "HPA038236: " "unprognostic (6.46e-2)" "unprognostic (3.61e-2)" "unprognostic (8.43e-2)" "unprognostic (1.36e-1)" "unprognostic (2.27e-3)" "unprognostic (2.59e-2)" "unprognostic (1.19e-1)" "potential prognostic favorable (7.62e-5)" "unprognostic (3.06e-2)" "unprognostic (4.44e-2)" "validated prognostic favorable (1.06e-5)" "validated prognostic favorable (7.22e-4)" "unprognostic (5.66e-2)" "unprognostic (2.83e-1)" "unprognostic (1.39e-1)" "unprognostic (1.60e-3)" "unprognostic (1.51e-3)" "unprognostic (6.80e-2)" "unprognostic (2.87e-1)" "unprognostic (8.70e-2)" "unprognostic (5.14e-2)" "unprognostic (3.56e-2)" "unprognostic (2.99e-2)" "unprognostic (7.42e-2)" "unprognostic (2.97e-2)" "unprognostic (6.79e-3)" "unprognostic (3.70e-1)" "unprognostic (3.38e-1)" "unprognostic (2.71e-1)" "potential prognostic unfavorable (8.11e-4)" "unprognostic (1.41e-1)" PARN DAN ENSG00000140694 "Poly(A)-specific ribonuclease" O95453 16 14435700-14632728 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Nonsense-mediated mRNA decay" "Exonuclease, Hydrolase, Nuclease, RNA-binding" "Disease variant, Dyskeratosis congenita" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 75.5;Brain excitatory neurons: 67.1;Brain inhibitory neurons: 67.8;Choroid plexus epithelial cells: 129.9;Distal convoluted tubule cells: 110.2;Ependymal cells: 91.5;Loop of henle epithelial cells: 87.0;Microglia: 113.6;Oligodendrocytes: 102.0;Papillary tip epithelial cells: 87.2;Podocytes: 101.7;Proximal tubule cells: 102.6;Renal collecting duct intercalated cells: 113.3;Renal collecting duct principal cells: 90.3;Renal connecting tubule cells: 108.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006314, CAB011673, HPA012010" Supported Supported "Nuclear speckles" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 22: Epididymis - Mixed function" "Cluster 55: Non-specific - Transcription" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 102: Non-specific - Mixed function" 24 "Nuclear speckles" "CAB011673: , HPA006314: , HPA012010: " "unprognostic (1.62e-2)" "unprognostic (6.29e-2)" "unprognostic (1.02e-1)" "unprognostic (1.30e-1)" "unprognostic (4.43e-2)" "unprognostic (1.05e-1)" "unprognostic (1.31e-1)" "unprognostic (6.36e-2)" "unprognostic (1.74e-3)" "unprognostic (3.66e-2)" "unprognostic (4.17e-2)" "unprognostic (1.50e-1)" "unprognostic (5.23e-2)" "unprognostic (1.40e-3)" "unprognostic (1.39e-1)" "unprognostic (6.93e-2)" "unprognostic (2.98e-1)" "unprognostic (1.72e-1)" "unprognostic (8.90e-2)" "unprognostic (3.52e-2)" "unprognostic (1.93e-2)" "unprognostic (1.65e-2)" "unprognostic (4.69e-3)" "unprognostic (1.70e-1)" "unprognostic (8.27e-3)" "unprognostic (1.94e-1)" "unprognostic (8.54e-2)" "potential prognostic unfavorable (9.22e-4)" "unprognostic (1.24e-2)" "unprognostic (1.57e-1)" "unprognostic (2.01e-1)" PARP1 "ADPRT, ARTD1, PARP, PARS, Poly-PARP, PPOL" ENSG00000143799 "Poly(ADP-ribose) polymerase 1" P09874 1 226360210-226408154 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, DNA damage, DNA repair, Immunity, Innate immunity, Transcription, Transcription regulation" "Allosteric enzyme, DNA-binding, Glycosyltransferase, Nucleotidyltransferase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 606.2;Migrating cytotrophoblasts: 329.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000147, CAB003839, CAB003840, HPA045168, CAB075726, CAB075727, CAB080368" Supported Supported Enhanced "Nucleoplasm,Nucleoli,Nucleoli fibrillar center,Nuclear bodies" NA NA 120000 "Cluster 14: Non-specific - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 548 Nucleoplasm "Nucleoli, Nucleoli fibrillar center, Nuclear bodies" "CAB000147: , CAB003839: , CAB003840: , CAB075726: , CAB075727: , CAB080368: , HPA045168: " "unprognostic (2.34e-1)" "unprognostic (3.23e-1)" "unprognostic (3.71e-1)" "unprognostic (2.67e-1)" "unprognostic (1.09e-2)" "unprognostic (4.56e-2)" "unprognostic (1.17e-1)" "unprognostic (1.81e-1)" "unprognostic (1.60e-1)" "unprognostic (3.72e-2)" "unprognostic (1.56e-3)" "unprognostic (5.57e-2)" "unprognostic (6.57e-2)" "unprognostic (1.15e-2)" "unprognostic (3.23e-3)" "unprognostic (6.09e-2)" "unprognostic (1.11e-3)" "unprognostic (4.18e-2)" "unprognostic (7.97e-3)" "unprognostic (3.00e-1)" "unprognostic (1.73e-1)" "unprognostic (1.51e-2)" "unprognostic (4.43e-2)" "unprognostic (3.51e-1)" "unprognostic (2.41e-2)" "unprognostic (1.73e-2)" "unprognostic (1.39e-1)" "unprognostic (1.64e-1)" "unprognostic (2.33e-1)" "unprognostic (2.56e-2)" "unprognostic (4.23e-1)" PARP10 "ARTD10, FLJ14464" ENSG00000178685 "Poly(ADP-ribose) polymerase family member 10" Q53GL7 8 143977153-144012772 "Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Glycosyltransferase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 170.6;Cardiomyocytes: 153.4;Early primary spermatocytes: 95.1;Epicardial cells: 88.7;Proximal tubule cells: 87.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 16.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Breast - T-cells" "Low region specificity" "Detected in many" "HPA028122, HPA052427" Approved Supported "Nucleoli rim,Golgi apparatus,Cytosol" No No "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 44: Non-specific - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 7 "Nucleoli rim" "Golgi apparatus, Cytosol" "HPA028122: , HPA052427: " "unprognostic (1.23e-3)" "unprognostic (1.26e-1)" "unprognostic (1.96e-2)" "unprognostic (1.02e-1)" "unprognostic (1.36e-1)" "unprognostic (1.16e-1)" "unprognostic (1.19e-1)" "unprognostic (3.26e-1)" "unprognostic (5.31e-2)" "unprognostic (2.74e-1)" "unprognostic (3.08e-2)" "unprognostic (5.65e-2)" "unprognostic (9.91e-3)" "unprognostic (3.62e-1)" "unprognostic (9.42e-3)" "unprognostic (2.00e-1)" "unprognostic (3.83e-2)" "unprognostic (8.03e-2)" "unprognostic (2.30e-1)" "unprognostic (3.25e-1)" "potential prognostic favorable (1.67e-4)" "unprognostic (1.41e-1)" "potential prognostic unfavorable (5.47e-4)" "unprognostic (4.67e-2)" "unprognostic (1.88e-1)" "unprognostic (3.95e-2)" "unprognostic (1.91e-1)" "unprognostic (4.13e-3)" "unprognostic (2.09e-2)" "unprognostic (7.76e-2)" "unprognostic (3.84e-2)" PARP11 "ARTD11, C12orf6" ENSG00000111224 "Poly(ADP-ribose) polymerase family member 11" Q9NR21 12 3791047-3873448 "Metabolic proteins, Predicted intracellular proteins" "Differentiation, mRNA transport, Protein transport, Spermatogenesis, Translocation, Transport" "Glycosyltransferase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Sertoli cells: 136.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026895 Uncertain Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 7: Non-specific - Ribosome" "Cluster 55: Lymphoma - Immune response" "Cluster 7: Non-specific - Transcription" 2 "Nuclear bodies" "Nucleoplasm, Cytosol" "HPA026895: " "unprognostic (5.48e-2)" "unprognostic (6.80e-2)" "unprognostic (2.58e-1)" "unprognostic (2.83e-3)" "unprognostic (1.12e-1)" "unprognostic (3.77e-2)" "unprognostic (6.93e-2)" "unprognostic (1.84e-1)" "unprognostic (3.65e-2)" "unprognostic (4.32e-3)" "unprognostic (1.51e-3)" "unprognostic (1.27e-1)" "unprognostic (1.10e-1)" "unprognostic (2.79e-2)" "unprognostic (4.59e-2)" "unprognostic (1.19e-1)" "unprognostic (8.14e-2)" "unprognostic (3.54e-2)" "unprognostic (2.13e-1)" "unprognostic (5.72e-2)" "unprognostic (3.19e-3)" "unprognostic (4.36e-1)" "potential prognostic unfavorable (8.71e-4)" "unprognostic (4.61e-2)" "unprognostic (3.92e-2)" "unprognostic (5.99e-2)" "unprognostic (1.53e-1)" "unprognostic (1.36e-1)" "unprognostic (2.07e-1)" "unprognostic (9.00e-3)" "unprognostic (3.72e-2)" PARP12 "ARTD12, FLJ22693, PARP-12, ZC3H1, ZC3HDC1" ENSG00000059378 "Poly(ADP-ribose) polymerase family member 12" Q9H0J9 7 140023749-140062951 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glycosyltransferase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 84.0" "Cell type enhanced" "Detected in many" "endothelial cell: 119.0;leukocyte: 53.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Skeletal muscle - Endothelial cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003584, HPA063872" Approved Approved Nucleoplasm NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 104: Brain endothelial cells - Blood brain barrier" 1 Nucleoplasm "HPA003584: , HPA063872: " "unprognostic (1.54e-1)" "unprognostic (1.06e-1)" "unprognostic (3.35e-1)" "unprognostic (1.11e-1)" "unprognostic (4.01e-2)" "unprognostic (1.11e-2)" "unprognostic (2.80e-1)" "unprognostic (1.38e-2)" "unprognostic (1.39e-1)" "unprognostic (1.80e-2)" "unprognostic (2.67e-2)" "unprognostic (7.94e-2)" "unprognostic (5.58e-2)" "potential prognostic unfavorable (5.26e-4)" "unprognostic (1.17e-1)" "unprognostic (4.68e-2)" "unprognostic (1.77e-2)" "unprognostic (1.10e-1)" "unprognostic (5.23e-2)" "unprognostic (2.03e-1)" "unprognostic (3.78e-2)" "unprognostic (7.77e-3)" "potential prognostic unfavorable (3.86e-4)" "unprognostic (5.28e-1)" "unprognostic (1.10e-1)" "unprognostic (1.92e-2)" "unprognostic (1.81e-2)" "unprognostic (1.59e-1)" "unprognostic (1.65e-1)" "unprognostic (1.97e-1)" "unprognostic (2.32e-3)" PARP14 "ARTD8, BAL2, KIAA1268, pART8" ENSG00000173193 "Poly(ADP-ribose) polymerase family member 14" Q460N5 3 122680839-122730840 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity, Transcription, Transcription regulation" "Glycosyltransferase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 415.6;B-cells: 251.3;Endometrial luminal cells: 252.6;Transitional alveolar cells: 262.0" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 314.3;endothelial cell: 385.0;leukocyte: 183.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008846, HPA012063" Supported Supported Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 1 Cytosol "HPA008846: , HPA012063: " "unprognostic (4.93e-2)" "unprognostic (1.50e-1)" "unprognostic (2.23e-1)" "unprognostic (5.27e-2)" "unprognostic (1.57e-1)" "unprognostic (1.18e-1)" "unprognostic (2.55e-1)" "unprognostic (2.73e-1)" "unprognostic (8.12e-2)" "unprognostic (1.33e-2)" "potential prognostic favorable (2.15e-8)" "unprognostic (9.67e-2)" "unprognostic (4.93e-2)" "unprognostic (1.83e-1)" "unprognostic (5.52e-2)" "unprognostic (2.53e-1)" "unprognostic (5.65e-3)" "unprognostic (1.14e-1)" "unprognostic (2.03e-1)" "unprognostic (1.67e-1)" "unprognostic (9.36e-2)" "validated prognostic unfavorable (6.95e-4)" "validated prognostic unfavorable (1.46e-5)" "unprognostic (3.54e-1)" "unprognostic (1.07e-3)" "unprognostic (1.27e-2)" "unprognostic (1.03e-1)" "unprognostic (1.40e-1)" "unprognostic (1.19e-1)" "unprognostic (8.68e-2)" "unprognostic (1.31e-1)" PARP15 "ARTD7, BAL3, FLJ40597, pART7" ENSG00000173200 "Poly(ADP-ribose) polymerase family member 15" Q460N3 3 122577628-122639047 "Metabolic proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Glycosyltransferase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 21.4;intestine: 36.9;lymphoid tissue: 59.7" "Cell type enhanced" "Detected in many" "B-cells: 279.1;Erythrocyte progenitors: 31.6;Hematopoietic stem cells: 39.3;Hofbauer cells: 31.6;Mast cells: 29.7;Megakaryocyte progenitors: 36.0;Megakaryocyte-Erythroid progenitors: 33.3;NK-cells: 113.6;T-cells: 66.8;Thymocytes: 27.1" "Cell type enriched" "Detected in some" 8 "leukocyte: 126.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 7 "Leukemia: 17.5;lymphoma: 15.2" "Adipose visceral - T-cells, Colon - T-cells, Kidney - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Spleen - B-cells (Spleen), Stomach - T-cells, Thyroid gland - T-cells" "Low region specificity" "Detected in all" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 9: Non-specific - Receptor signaling" "Cluster 55: Lymphoma - Immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" "unprognostic (8.74e-2)" "unprognostic (5.55e-2)" "unprognostic (3.33e-2)" "unprognostic (8.33e-2)" "unprognostic (2.64e-2)" "unprognostic (9.70e-2)" "unprognostic (2.79e-1)" "unprognostic (2.31e-1)" "unprognostic (2.45e-2)" "unprognostic (6.00e-3)" "potential prognostic unfavorable (8.57e-5)" "unprognostic (2.07e-1)" "unprognostic (1.82e-1)" "unprognostic (1.61e-1)" "unprognostic (2.85e-3)" "potential prognostic favorable (8.42e-6)" "unprognostic (3.17e-2)" "unprognostic (2.83e-1)" "unprognostic (2.02e-1)" "unprognostic (3.75e-2)" "unprognostic (1.43e-2)" "unprognostic (6.13e-2)" "unprognostic (1.71e-2)" "unprognostic (4.02e-2)" "unprognostic (5.93e-2)" "potential prognostic favorable (4.39e-4)" "unprognostic (2.01e-1)" "unprognostic (1.27e-1)" "unprognostic (1.11e-1)" "unprognostic (1.77e-1)" "unprognostic (7.72e-2)" PARP16 "ARTD15, C15orf30, FLJ20509, FLJ25281, pART15" ENSG00000138617 "Poly(ADP-ribose) polymerase family member 16" Q8N5Y8 15 65234460-65300618 "Metabolic proteins, Predicted membrane proteins" "Unfolded protein response" "Glycosyltransferase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 88.7;Oocytes: 101.3;Rod photoreceptor cells: 131.8;Undifferentiated spermatogonia: 72.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017081 Approved NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 75: Ovary - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 79: Photoreceptor cells - Phototransduction" 3 "HPA017081: " "unprognostic (5.45e-3)" "unprognostic (1.38e-1)" "unprognostic (4.41e-2)" "unprognostic (8.78e-2)" "unprognostic (5.66e-3)" "unprognostic (6.93e-2)" "unprognostic (7.02e-3)" "unprognostic (7.45e-2)" "unprognostic (2.66e-2)" "unprognostic (1.38e-2)" "unprognostic (3.99e-2)" "unprognostic (2.18e-2)" "unprognostic (4.43e-2)" "unprognostic (7.33e-2)" "potential prognostic unfavorable (1.39e-4)" "unprognostic (2.54e-1)" "unprognostic (2.94e-2)" "unprognostic (1.63e-1)" "unprognostic (3.76e-1)" "unprognostic (2.18e-1)" "unprognostic (2.38e-2)" "unprognostic (1.08e-1)" "unprognostic (1.15e-1)" "unprognostic (1.64e-1)" "unprognostic (3.25e-2)" "unprognostic (1.61e-1)" "unprognostic (5.06e-2)" "unprognostic (5.57e-2)" "unprognostic (3.81e-2)" "unprognostic (6.85e-3)" "unprognostic (1.12e-1)" PARP2 "ADPRTL2, ARTD2" ENSG00000129484 "Poly(ADP-ribose) polymerase 2" Q9UGN5 14 20343615-20357904 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Allosteric enzyme, DNA-binding, Glycosyltransferase, Nucleotidyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 60.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018137, HPA052003" Approved Supported Nucleoplasm,Nucleoli NA Yes "Cluster 33: Non-specific - ATP binding" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 34: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 27: Non-specific - Cell proliferation" 20 Nucleoplasm Nucleoli "HPA018137: , HPA052003: " "unprognostic (9.96e-3)" "unprognostic (1.16e-1)" "unprognostic (5.10e-2)" "unprognostic (6.78e-3)" "unprognostic (3.18e-1)" "unprognostic (2.14e-1)" "unprognostic (7.42e-2)" "unprognostic (1.41e-2)" "unprognostic (1.95e-2)" "potential prognostic unfavorable (5.68e-4)" "unprognostic (1.17e-2)" "unprognostic (7.87e-2)" "unprognostic (8.50e-2)" "validated prognostic unfavorable (1.10e-4)" "validated prognostic unfavorable (1.51e-4)" "unprognostic (1.00e-2)" "unprognostic (1.84e-2)" "unprognostic (1.17e-1)" "unprognostic (1.61e-3)" "unprognostic (1.83e-2)" "unprognostic (2.31e-1)" "unprognostic (6.35e-2)" "unprognostic (2.83e-3)" "unprognostic (4.44e-2)" "unprognostic (3.94e-1)" "unprognostic (2.16e-1)" "unprognostic (2.25e-2)" "unprognostic (1.47e-1)" "unprognostic (7.45e-2)" "unprognostic (1.23e-1)" "unprognostic (3.76e-1)" PARP3 "ADPRT3, ADPRTL3, ARTD3, hPARP-3, IRT1, pADPRT-3" ENSG00000041880 "Poly(ADP-ribose) polymerase family member 3" Q9Y6F1 3 51942345-51948867 "FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Glycosyltransferase, Nucleotidyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 30.7;Foveolar cells: 21.5;Late spermatids: 20.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020984, HPA067657" Supported Supported "Nucleoplasm,Nuclear bodies" Yes No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 76: Non-specific - Metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 1: Enterocytes - Absorption and Digestion" 5 "Nucleoplasm, Nuclear bodies" "HPA020984: , HPA067657: " "potential prognostic favorable (8.19e-4)" "unprognostic (1.18e-3)" "unprognostic (2.30e-2)" "unprognostic (2.42e-1)" "unprognostic (1.24e-1)" "unprognostic (3.87e-2)" "unprognostic (1.59e-1)" "unprognostic (1.89e-2)" "unprognostic (1.26e-1)" "unprognostic (2.23e-2)" "unprognostic (1.89e-1)" "unprognostic (1.85e-1)" "potential prognostic favorable (5.91e-8)" "unprognostic (5.75e-2)" "unprognostic (1.39e-3)" "unprognostic (3.45e-2)" "unprognostic (5.22e-2)" "unprognostic (1.61e-2)" "unprognostic (1.54e-1)" "unprognostic (8.89e-2)" "unprognostic (9.98e-2)" "unprognostic (1.61e-3)" "unprognostic (2.30e-1)" "unprognostic (4.30e-1)" "unprognostic (5.67e-2)" "unprognostic (2.17e-2)" "unprognostic (2.78e-1)" "unprognostic (1.35e-1)" "unprognostic (2.85e-1)" "unprognostic (3.21e-2)" "unprognostic (8.41e-3)" PARP4 "ADPRTL1, ARTD4, p193, VAULT3, VPARP, VWA5C" ENSG00000102699 "Poly(ADP-ribose) polymerase family member 4" Q9UKK3 13 24420931-24512778 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Nucleotidyltransferase, Ribonucleoprotein, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Mast cells: 338.6;Neutrophil progenitors: 350.1;Neutrophils: 656.7" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 170.8;leukocyte: 162.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011739 Approved Supported "Nucleoplasm,Microtubules,Mitotic spindle,Primary cilium,Cytosol" Yes No "Cluster 42: Non-specific - Vesicular transport" "Cluster 77: Intestine - Digestion" "Cluster 30: White matter - Myelination" "Cluster 19: Non-specific - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" 7 "Nucleoplasm, Microtubules, Cytosol" "Mitotic spindle, Primary cilium" "HPA011739: " "unprognostic (2.32e-1)" "unprognostic (2.02e-1)" "unprognostic (3.35e-1)" "unprognostic (1.06e-2)" "unprognostic (1.94e-1)" "unprognostic (3.90e-2)" "unprognostic (3.39e-1)" "unprognostic (1.10e-2)" "unprognostic (3.00e-1)" "unprognostic (2.55e-2)" "potential prognostic favorable (1.47e-7)" "unprognostic (2.20e-2)" "unprognostic (1.10e-2)" "unprognostic (8.04e-2)" "unprognostic (1.15e-2)" "unprognostic (6.54e-2)" "unprognostic (3.30e-3)" "unprognostic (7.73e-2)" "unprognostic (2.16e-1)" "unprognostic (2.94e-3)" "unprognostic (5.88e-3)" "potential prognostic unfavorable (6.30e-4)" "unprognostic (1.79e-1)" "unprognostic (5.67e-2)" "unprognostic (4.81e-3)" "unprognostic (7.13e-2)" "unprognostic (1.65e-1)" "unprognostic (7.76e-2)" "unprognostic (3.22e-1)" "unprognostic (6.48e-2)" "unprognostic (2.09e-1)" PARP6 "ARTD17, pART17" ENSG00000137817 "Poly(ADP-ribose) polymerase family member 6" Q2NL67 15 72241181-72272999 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 310.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026991 Approved Approved "Plasma membrane" Yes No "Cluster 25: Non-specific - Unknown function" "Cluster 27: Cerebellum - Synaptic function" "Cluster 34: Non-specific - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" "Plasma membrane" "HPA026991: " "unprognostic (2.52e-1)" "unprognostic (2.15e-1)" "unprognostic (6.11e-2)" "unprognostic (2.73e-2)" "potential prognostic unfavorable (7.07e-4)" "unprognostic (3.35e-2)" "unprognostic (1.22e-1)" "unprognostic (1.33e-3)" "unprognostic (6.58e-2)" "unprognostic (9.71e-3)" "unprognostic (2.02e-3)" "unprognostic (5.04e-3)" "unprognostic (2.42e-1)" "unprognostic (2.02e-2)" "unprognostic (1.95e-2)" "unprognostic (1.16e-1)" "unprognostic (5.07e-2)" "unprognostic (1.68e-1)" "unprognostic (7.33e-3)" "unprognostic (8.40e-2)" "unprognostic (5.16e-3)" "unprognostic (1.19e-2)" "unprognostic (7.58e-3)" "unprognostic (2.61e-2)" "unprognostic (9.84e-2)" "unprognostic (8.22e-2)" "unprognostic (9.86e-2)" "unprognostic (8.90e-2)" "unprognostic (1.14e-1)" "unprognostic (7.41e-2)" "unprognostic (5.52e-3)" PARP8 "ARTD16, FLJ21308, pART16" ENSG00000151883 "Poly(ADP-ribose) polymerase family member 8" Q8N3A8 5 50665899-50846519 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 81.6" "Cell type enhanced" "Detected in many" "Innate lymphoid cells: 612.5;Neutrophil progenitors: 717.1;Neutrophils: 1886.6;NK-cells: 1462.3;T-cells: 1713.9" "Cell type enhanced" "Detected in all" "leukocyte: 1862.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Prostate - T-cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049183 Approved Approved "Nucleoplasm,Midbody ring,Cytosol" Yes No "Cluster 1: T-cells - Unknown function" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 29: Forebrain - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 2 Nucleoplasm "Midbody ring, Cytosol" "HPA049183: " "unprognostic (2.40e-1)" "unprognostic (2.86e-2)" "unprognostic (1.00e-1)" "unprognostic (2.46e-1)" "unprognostic (2.90e-1)" "unprognostic (2.99e-1)" "unprognostic (1.63e-1)" "unprognostic (6.21e-3)" "unprognostic (1.75e-2)" "unprognostic (2.16e-1)" "unprognostic (1.44e-1)" "unprognostic (2.09e-1)" "unprognostic (2.00e-2)" "unprognostic (8.36e-2)" "unprognostic (9.49e-2)" "unprognostic (2.01e-3)" "unprognostic (4.70e-2)" "unprognostic (3.49e-3)" "unprognostic (3.38e-1)" "unprognostic (3.97e-2)" "unprognostic (3.27e-1)" "unprognostic (1.81e-1)" "unprognostic (1.31e-2)" "unprognostic (3.70e-2)" "unprognostic (2.03e-2)" "unprognostic (3.48e-2)" "unprognostic (2.97e-1)" "unprognostic (2.34e-2)" "unprognostic (3.02e-1)" "unprognostic (9.15e-2)" "unprognostic (1.13e-1)" PARP9 "ARTD9, BAL, BAL1" ENSG00000138496 "Poly(ADP-ribose) polymerase family member 9" Q8IXQ6 3 122527924-122564577 "Disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, DNA damage, DNA repair, Immunity, Innate immunity" "Glycosyltransferase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 165.1" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 85.7;endothelial cell: 224.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA066708 Supported Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 5 "Nucleoplasm, Cytosol" Mitochondria "HPA066708: " "unprognostic (6.51e-2)" "unprognostic (5.26e-2)" "unprognostic (2.30e-1)" "unprognostic (1.46e-2)" "unprognostic (1.98e-1)" "unprognostic (1.09e-1)" "unprognostic (1.34e-1)" "unprognostic (1.03e-1)" "unprognostic (5.58e-2)" "unprognostic (9.19e-3)" "unprognostic (9.65e-3)" "unprognostic (2.50e-1)" "unprognostic (1.78e-1)" "unprognostic (1.32e-2)" "unprognostic (7.84e-3)" "unprognostic (7.97e-3)" "unprognostic (7.02e-2)" "unprognostic (2.68e-2)" "unprognostic (8.41e-2)" "unprognostic (1.54e-2)" "unprognostic (2.84e-1)" "unprognostic (1.93e-3)" "unprognostic (4.44e-3)" "unprognostic (1.56e-2)" "unprognostic (3.71e-1)" "unprognostic (2.72e-2)" "unprognostic (4.22e-1)" "unprognostic (1.48e-1)" "unprognostic (8.53e-3)" "unprognostic (2.05e-2)" "unprognostic (2.68e-2)" PARPBP "C12orf48, FLJ20641, PARI" ENSG00000185480 "PARP1 binding protein" Q9NWS1 12 102120183-102197520 "Predicted intracellular proteins" "DNA damage, DNA repair" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 8.8;lymphoid tissue: 7.0" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 54.4;Enteric transient amplifying cells: 39.6;Erythrocyte progenitors: 116.0;Megakaryocyte progenitors: 80.2;Monocyte progenitors: 100.7;Neutrophil progenitors: 72.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA039677 Approved Supported Nucleoplasm NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 38: Non-specific - Transcription" "Cluster 27: Non-specific - Cell proliferation" 2 Nucleoplasm "HPA039677: " "unprognostic (2.50e-1)" "unprognostic (2.14e-2)" "unprognostic (1.61e-1)" "unprognostic (1.94e-2)" "unprognostic (8.71e-2)" "unprognostic (4.95e-1)" "unprognostic (6.62e-2)" "unprognostic (2.97e-1)" "unprognostic (6.94e-3)" "validated prognostic unfavorable (6.49e-5)" "validated prognostic unfavorable (7.89e-6)" "potential prognostic unfavorable (4.19e-4)" "potential prognostic unfavorable (1.64e-5)" "potential prognostic unfavorable (9.00e-6)" "unprognostic (1.63e-2)" "potential prognostic favorable (3.82e-4)" "unprognostic (1.63e-3)" "unprognostic (1.46e-1)" "unprognostic (1.07e-2)" "unprognostic (9.53e-3)" "unprognostic (2.99e-3)" "unprognostic (2.83e-2)" "unprognostic (5.67e-2)" "unprognostic (3.41e-3)" "unprognostic (4.37e-2)" "unprognostic (3.99e-1)" "unprognostic (1.86e-1)" PARS2 DKFZp727A071 ENSG00000162396 "Prolyl-tRNA synthetase 2, mitochondrial" Q7L3T8 1 54756898-54764523 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 16.0;Late primary spermatocytes: 13.1;Retinal horizontal cells: 16.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028308, HPA028314, HPA028518" Uncertain Approved "Nucleoli fibrillar center,Mitochondria" No No "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 37: Non-specific - mRNA processing" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 13 "Nucleoli fibrillar center, Mitochondria" "HPA028308: , HPA028314: , HPA028518: " "unprognostic (1.23e-1)" "unprognostic (1.45e-1)" "unprognostic (1.31e-1)" "unprognostic (5.49e-2)" "unprognostic (1.29e-3)" "unprognostic (1.28e-1)" "unprognostic (2.60e-2)" "unprognostic (1.20e-2)" "unprognostic (2.06e-3)" "unprognostic (5.37e-3)" "validated prognostic favorable (3.68e-7)" "validated prognostic favorable (8.90e-4)" "unprognostic (5.97e-3)" "potential prognostic unfavorable (1.16e-4)" "unprognostic (5.78e-3)" "unprognostic (7.12e-2)" "unprognostic (7.32e-3)" "unprognostic (3.11e-1)" "unprognostic (1.32e-2)" "unprognostic (9.16e-2)" "unprognostic (1.81e-1)" "unprognostic (9.07e-2)" "unprognostic (3.05e-3)" "unprognostic (8.99e-2)" "potential prognostic favorable (2.74e-5)" "unprognostic (3.51e-2)" "unprognostic (3.46e-1)" "unprognostic (6.90e-2)" "unprognostic (1.55e-1)" "unprognostic (1.49e-1)" "unprognostic (4.57e-1)" PARVA "FLJ10793, FLJ12254, MXRA2" ENSG00000197702 "Parvin alpha" Q9NVD7 11 12377563-12535356 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Cell adhesion, Cell shape, Chemotaxis, Cilium biogenesis/degradation" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 332.0;Pituitary stem cells: 402.1;Podocytes: 463.0;Smooth muscle cells: 385.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "MAIT T-cell: 1.0" "Lineage enriched" "Detected in single" 11 "T-cells: 1.0" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Fibroblasts, Breast - Adipocytes (Breast), Prostate - Smooth muscle cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005964 Approved Supported "Actin filaments,Focal adhesion sites,Cytosol" NA NA 2700000 "Cluster 27: T-cells - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 57: Podocytes - Glomerular filtration" 19 "Actin filaments, Focal adhesion sites" Cytosol "HPA005964: " "unprognostic (9.36e-2)" "unprognostic (1.12e-1)" "unprognostic (2.98e-2)" "unprognostic (2.52e-2)" "unprognostic (1.87e-1)" "unprognostic (5.59e-2)" "unprognostic (6.02e-2)" "unprognostic (2.94e-3)" "unprognostic (5.23e-2)" "potential prognostic unfavorable (4.47e-4)" "potential prognostic favorable (1.14e-7)" "unprognostic (2.24e-3)" "unprognostic (1.52e-1)" "unprognostic (6.27e-2)" "unprognostic (2.11e-3)" "unprognostic (7.30e-2)" "unprognostic (2.77e-2)" "potential prognostic unfavorable (8.21e-5)" "unprognostic (1.83e-1)" "unprognostic (1.42e-2)" "unprognostic (6.14e-3)" "unprognostic (4.72e-2)" "unprognostic (6.38e-2)" "unprognostic (1.16e-1)" "unprognostic (8.38e-2)" "unprognostic (6.36e-2)" "unprognostic (8.42e-2)" "unprognostic (1.99e-3)" "unprognostic (1.17e-1)" "unprognostic (3.32e-1)" "unprognostic (4.17e-2)" PARVB CGI-56 ENSG00000188677 "Parvin beta" Q9HBI1 22 43999211-44172939 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" Actin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 183.6;tongue: 159.4" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 307.3;Mast cells: 211.9;Megakaryocyte progenitors: 192.1;Megakaryocytes: 1193.1;Myonuclei: 227.5;pDCs: 213.6;Platelets: 751.8" "Cell type enhanced" "Detected in all" "endothelial cell: 188.8" "Group enriched" "Detected in all" 4 "Kidney Chromophobe (TCGA): 138.3;Skin Cutaneous Melanoma (TCGA): 127.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Minor Salivary Gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003568, HPA072217" Enhanced Supported "Plasma membrane,Actin filaments" NA NA 26000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 47: Platelets - Hemostasis" 8 "Plasma membrane, Actin filaments" "HPA003568: , HPA072217: " "unprognostic (1.18e-1)" "unprognostic (1.05e-1)" "unprognostic (4.17e-2)" "unprognostic (1.42e-3)" "unprognostic (1.56e-1)" "unprognostic (1.30e-2)" "unprognostic (2.67e-3)" "potential prognostic unfavorable (9.06e-4)" "unprognostic (3.54e-3)" "unprognostic (1.70e-1)" "unprognostic (5.94e-3)" "unprognostic (3.67e-2)" "unprognostic (8.94e-2)" "unprognostic (2.93e-2)" "unprognostic (1.86e-1)" "unprognostic (1.05e-2)" "unprognostic (6.73e-2)" "unprognostic (1.48e-1)" "unprognostic (1.17e-2)" "unprognostic (1.56e-1)" "unprognostic (2.97e-2)" "unprognostic (6.05e-3)" "unprognostic (5.04e-3)" "unprognostic (1.32e-1)" "unprognostic (1.51e-1)" "unprognostic (1.18e-2)" "unprognostic (1.43e-1)" "unprognostic (4.60e-2)" "unprognostic (3.57e-2)" "unprognostic (5.26e-2)" "unprognostic (1.52e-1)" PARVG ENSG00000138964 "Parvin gamma" Q9HBI0 22 44172956-44219533 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 46.9;lymphoid tissue: 28.1" "Cell type enhanced" "Detected in many" "B-cells: 65.0;cDC: 124.8;Hematopoietic stem cells: 51.9;Hofbauer cells: 68.9;Kupffer cells: 91.2;Macrophages: 98.3;Microglia: 85.6;Monocyte progenitors: 142.8;monocytes: 139.2;Neutrophil progenitors: 95.1;Neutrophils: 85.9;NK-cells: 50.3;pDCs: 108.8;T-cells: 54.6;Thymocytes: 55.1" "Group enriched" "Detected in many" 19 "central nervous system macrophage: 111.5;leukocyte: 73.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in some" 6 "Leukemia: 55.5" "Adipose subcutaneous - Macrophages, Adrenal gland - Macrophages, Prostate - T-cells, Skeletal muscle - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA031833, HPA031834" Uncertain NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 33 "HPA031833: , HPA031834: " "unprognostic (4.53e-2)" "unprognostic (4.22e-2)" "unprognostic (1.21e-2)" "unprognostic (2.26e-3)" "unprognostic (2.34e-1)" "unprognostic (1.24e-1)" "unprognostic (6.66e-3)" "unprognostic (1.93e-1)" "unprognostic (1.33e-2)" "unprognostic (8.82e-2)" "unprognostic (1.30e-2)" "unprognostic (3.47e-1)" "unprognostic (1.54e-2)" "unprognostic (1.40e-2)" "potential prognostic favorable (7.59e-4)" "unprognostic (4.93e-2)" "unprognostic (5.86e-2)" "unprognostic (3.51e-1)" "unprognostic (3.06e-1)" "unprognostic (1.77e-1)" "unprognostic (2.16e-2)" "unprognostic (4.41e-3)" "unprognostic (1.52e-1)" "unprognostic (1.35e-1)" "unprognostic (5.05e-2)" "unprognostic (3.13e-1)" "unprognostic (2.93e-1)" "unprognostic (2.95e-2)" "unprognostic (5.70e-2)" "unprognostic (1.62e-3)" PASD1 CT63 ENSG00000166049 "PAS domain containing repressor 1" Q8IV76 X 151563675-151676739 "Predicted intracellular proteins" "Biological rhythms" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 151 "testis: 15.0" "Group enriched" "Detected in some" 66 "Differentiating spermatogonia: 83.5;Early primary spermatocytes: 43.3;Undifferentiated spermatogonia: 60.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Skin Cutaneous Melanoma (TCGA): 1.9;Testicular Germ Cell Tumor (TCGA): 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 9.0;skin cancer: 5.8" "Testis - Spermatogonia" "Not detected" "Not detected" "HPA011122, HPA011152" Enhanced Enhanced "Nuclear speckles" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 106: Spermatogonia - Spermatogonial differentiation" "Nuclear speckles" "HPA011122: , HPA011152: " "unprognostic (1.67e-2)" "unprognostic (2.17e-1)" PASK "KIAA0135, PASKIN, STK37" ENSG00000115687 "PAS domain containing serine/threonine kinase" Q96RG2 2 241106099-241150264 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 21.3" "Cell type enhanced" "Detected in many" "Ependymal cells: 32.1;Late primary spermatocytes: 28.3;Peritubular myoid cells: 29.0;Prostatic glandular cells: 27.5;Rod photoreceptor cells: 28.3;T-cells: 30.6;Vascular endothelial cells: 36.5" "Cell type enhanced" "Detected in many" "medium spiny neuron: 49.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Spleen - B-cells (Spleen), Testis - Spermatocytes" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA016450, HPA021079" Uncertain Supported Cytosol NA Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 33: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 12 Cytosol "HPA016450: , HPA021079: " "unprognostic (3.38e-2)" "unprognostic (1.66e-1)" "unprognostic (2.44e-2)" "unprognostic (3.89e-1)" "unprognostic (1.93e-1)" "unprognostic (1.01e-2)" "unprognostic (8.19e-2)" "unprognostic (2.64e-1)" "potential prognostic favorable (2.67e-4)" "unprognostic (2.08e-1)" "unprognostic (6.02e-3)" "unprognostic (8.79e-3)" "unprognostic (1.74e-1)" "potential prognostic unfavorable (5.76e-4)" "unprognostic (1.40e-1)" "unprognostic (2.86e-1)" "unprognostic (5.25e-1)" "unprognostic (2.34e-1)" "unprognostic (2.94e-2)" "unprognostic (2.19e-1)" "unprognostic (7.04e-3)" "unprognostic (9.95e-2)" "potential prognostic unfavorable (4.06e-4)" "unprognostic (6.67e-2)" "unprognostic (5.97e-3)" "unprognostic (3.79e-2)" "unprognostic (4.67e-3)" "unprognostic (3.63e-2)" "unprognostic (2.70e-1)" "unprognostic (3.44e-2)" "unprognostic (2.09e-2)" PATE1 PATE ENSG00000171053 "Prostate and testis expressed 1" Q8WXA2 11 125746279-125749867 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "epididymis: 1764.3" "Cell type enriched" "Detected in some" 122 "Epididymal principal cells: 1634.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA076587 Approved "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" 3 "HPA076587: " PATE2 "C11orf38, LVLF3112, PATE-M, UNQ3112" ENSG00000196844 "Prostate and testis expressed 2" Q6UY27 11 125776113-125778828 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "epididymis: 425.2" "Cell type enriched" "Detected in some" 21 "Epididymal principal cells: 599.7" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 1.4;prostate cancer: 1.2" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" "potential prognostic favorable (2.76e-4)" "unprognostic (2.87e-1)" PATE3 "HEL-127, PATE-DJ" ENSG00000236027 "Prostate and testis expressed 3" B3GLJ2 11 125788127-125791600 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 34 "epididymis: 149.3" "Cell type enriched" "Detected in some" 39 "Epididymal principal cells: 84.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" PATE4 "FLJ41047, PATE-B" ENSG00000237353 "Prostate and testis expressed 4" P0C8F1 11 125833316-125840072 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "seminal vesicle: 100.5" "Cell type enriched" "Detected in some" 10 "Epididymal principal cells: 286.2" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Kidney Renal Clear Cell Carcinoma (TCGA): 2.8;Kidney Renal Papillary Cell Carcinoma (TCGA): 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "thyroid cancer: 1.6" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" HPA045632 Approved "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 38: Non-specific - Basic cellular processes" "Cluster 9: Non-specific - Receptor signaling" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" "HPA045632: " "unprognostic (2.79e-2)" "potential prognostic favorable (4.17e-10)" "potential prognostic favorable (4.60e-4)" "unprognostic (1.29e-1)" PATJ "Cipp, INADL" ENSG00000132849 "PATJ crumbs cell polarity complex component" Q8NI35 1 61742477-62178675 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubule cells: 1347.0" "Cell type enhanced" "Detected in all" "upper rhombic lip: 969.6" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 161.2" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 1, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 93.4" "HPA066352, HPA066960, HPA069079" Approved Supported "Cell Junctions,Centriolar satellite,Cytosol" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 25: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 16 "Cell Junctions" "Centriolar satellite, Cytosol" "HPA066352: , HPA066960: , HPA069079: " "unprognostic (2.76e-3)" "unprognostic (2.93e-1)" "potential prognostic unfavorable (1.80e-4)" "unprognostic (3.12e-1)" "unprognostic (4.59e-1)" "unprognostic (2.10e-1)" "unprognostic (9.60e-3)" "unprognostic (6.40e-2)" "unprognostic (5.91e-2)" "validated prognostic favorable (1.46e-5)" "validated prognostic favorable (2.34e-4)" "unprognostic (1.45e-1)" "unprognostic (2.43e-3)" "unprognostic (1.73e-1)" "unprognostic (5.82e-3)" "unprognostic (1.02e-1)" "unprognostic (2.15e-1)" "unprognostic (1.18e-1)" "unprognostic (1.11e-1)" "potential prognostic unfavorable (3.89e-4)" "unprognostic (1.26e-1)" "unprognostic (5.60e-2)" "unprognostic (1.11e-1)" "unprognostic (3.24e-1)" "unprognostic (5.03e-2)" "potential prognostic favorable (9.95e-4)" "unprognostic (9.75e-3)" "unprognostic (8.67e-2)" "unprognostic (1.08e-1)" PATL1 "FLJ36874, Pat1b" ENSG00000166889 "PAT1 homolog 1, processing body mRNA decay factor" Q86TB9 11 59636716-59669037 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 192.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039030, HPA074680" Approved Supported "Cytoplasmic bodies" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 48 "Cytoplasmic bodies" "HPA039030: , HPA074680: " "unprognostic (1.16e-1)" "unprognostic (1.13e-1)" "unprognostic (7.16e-2)" "unprognostic (1.20e-2)" "unprognostic (8.53e-2)" "unprognostic (1.11e-1)" "unprognostic (9.50e-2)" "unprognostic (1.46e-1)" "unprognostic (2.26e-1)" "potential prognostic unfavorable (6.39e-4)" "potential prognostic favorable (7.18e-4)" "unprognostic (2.88e-1)" "unprognostic (4.82e-2)" "unprognostic (5.60e-3)" "unprognostic (1.10e-1)" "unprognostic (1.20e-2)" "unprognostic (1.04e-3)" "unprognostic (2.94e-1)" "unprognostic (2.39e-1)" "unprognostic (7.07e-2)" "unprognostic (1.22e-1)" "validated prognostic unfavorable (6.22e-4)" "validated prognostic unfavorable (3.92e-5)" "unprognostic (2.54e-2)" "unprognostic (7.91e-3)" "unprognostic (2.64e-1)" "unprognostic (1.77e-1)" "unprognostic (1.72e-1)" "unprognostic (1.22e-1)" "unprognostic (1.11e-1)" "unprognostic (4.97e-2)" PATL2 Pat1a ENSG00000229474 "PAT1 homolog 2" C9JE40 15 44665732-44711323 "Disease related genes, Human disease related genes, Predicted intracellular proteins" RNA-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 7.3;lymphoid tissue: 15.9" "Cell type enhanced" "Detected in many" "B-cells: 23.3;Choroid plexus epithelial cells: 13.1;Ependymal cells: 14.4;Microglia: 20.2;Neutrophils: 21.5;NK-cells: 25.7;Oocytes: 96.7;T-cells: 21.9" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 27.9;leukocyte: 50.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Leukemia: 3.1;lymphoma: 4.9;Myeloma: 11.9" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Prostate - T-cells, Spleen - B-cells (Spleen), Thyroid gland - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 50: Lymphoma - Unknown function" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" "unprognostic (2.00e-2)" "unprognostic (9.72e-3)" "unprognostic (1.54e-1)" "unprognostic (9.76e-3)" "unprognostic (1.18e-1)" "unprognostic (6.83e-2)" "unprognostic (3.09e-1)" "unprognostic (4.14e-2)" "unprognostic (1.74e-3)" "unprognostic (3.09e-3)" "unprognostic (9.10e-2)" "unprognostic (2.12e-2)" "unprognostic (3.47e-1)" "unprognostic (4.34e-3)" "unprognostic (3.19e-2)" "unprognostic (4.03e-3)" "unprognostic (4.57e-2)" "unprognostic (2.16e-1)" "unprognostic (4.53e-2)" "unprognostic (1.05e-1)" PATZ1 "dJ400N23, MAZR, PATZ, RIAZ, ZBTB19, ZNF278, ZSG" ENSG00000100105 "POZ/BTB and AT hook containing zinc finger 1" Q9HBE1 22 31325804-31346346 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells, Liver - Hepatocytes, Spleen - B-cells (Spleen), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047893, HPA048315" Approved Supported Nucleoplasm No No "Cluster 30: Non-specific - DNA binding" "Cluster 61: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 4: Breast lactating luminal cells - Lactation" 7 Nucleoplasm "HPA047893: , HPA048315: " "unprognostic (2.12e-2)" "unprognostic (9.28e-2)" "unprognostic (4.14e-1)" "unprognostic (9.04e-2)" "unprognostic (3.26e-1)" "unprognostic (2.04e-1)" "unprognostic (4.19e-2)" "unprognostic (2.28e-3)" "unprognostic (2.01e-1)" "unprognostic (2.26e-1)" "validated prognostic favorable (1.86e-7)" "validated prognostic favorable (5.25e-4)" "unprognostic (6.03e-3)" "unprognostic (1.55e-2)" "unprognostic (5.58e-3)" "unprognostic (2.00e-1)" "unprognostic (2.74e-1)" "unprognostic (5.77e-3)" "potential prognostic favorable (1.16e-4)" "unprognostic (3.49e-1)" "unprognostic (3.47e-1)" "unprognostic (1.76e-1)" "unprognostic (1.12e-1)" "unprognostic (2.56e-1)" "unprognostic (1.31e-3)" "unprognostic (2.26e-1)" "unprognostic (1.41e-1)" "unprognostic (1.42e-1)" "unprognostic (1.45e-1)" "unprognostic (1.02e-1)" "unprognostic (4.12e-2)" PAWR "par-4, PAR4" ENSG00000177425 "Pro-apoptotic WT1 regulator" Q96IZ0 12 79574979-79690964 "Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 525.6;Endometrial glandular cells: 585.6;Epididymal basal cells: 740.2;Podocytes: 689.9" "Cell type enhanced" "Detected in many" "pericyte: 263.1;vascular associated smooth muscle cell: 264.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "memory B-cell: 2.7;naive B-cell: 2.8;NK-cell: 1.4" "Group enriched" "Detected in many" 5 "B-cells: 2.8;NK-cells: 1.4" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012640, CAB020779" Approved Supported "Plasma membrane,Actin filaments,Primary cilium tip,Cytosol" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 72: Neuronal - Signal transduction" "Cluster 51: Secretory epithelial cells - Mixed function" 34 "Actin filaments, Cytosol" "Plasma membrane, Primary cilium tip" "CAB020779: , HPA012640: " "unprognostic (2.06e-1)" "unprognostic (2.08e-1)" "unprognostic (1.42e-2)" "potential prognostic unfavorable (9.65e-4)" "unprognostic (2.02e-2)" "unprognostic (6.95e-2)" "unprognostic (2.95e-2)" "unprognostic (1.93e-1)" "unprognostic (1.67e-1)" "unprognostic (1.36e-1)" "unprognostic (1.11e-2)" "potential prognostic favorable (5.02e-4)" "unprognostic (1.35e-2)" "unprognostic (8.52e-2)" "unprognostic (4.50e-2)" "unprognostic (5.60e-3)" "unprognostic (3.78e-2)" "unprognostic (3.15e-2)" "unprognostic (2.09e-2)" "unprognostic (9.26e-2)" "unprognostic (1.01e-2)" "unprognostic (1.53e-2)" "unprognostic (3.53e-2)" "unprognostic (9.66e-2)" "unprognostic (5.91e-3)" "unprognostic (2.60e-1)" "unprognostic (4.30e-1)" "unprognostic (2.53e-1)" "unprognostic (3.81e-1)" "unprognostic (2.91e-2)" "unprognostic (1.96e-1)" PAX1 ENSG00000125813 "Paired box 1" P15863 20 21705659-21718481 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Deafness, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "parathyroid gland: 152.5" "Cell type enriched" "Detected in some" 8 "Medullary thymic epithelial cells: 72.0" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Head and Neck Squamous Cell Carcinoma (TCGA): 3.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 69: Parathyroid gland - Mixed function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 4 "unprognostic (1.10e-1)" "unprognostic (2.37e-1)" PAX2 PAX-2 ENSG00000075891 "Paired box 2" Q02962 10 100735396-100829944 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "epididymis: 28.0;kidney: 94.2" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 142.0;Endometrial glandular cells: 152.3;Endometrial luminal cells: 543.6;Epididymal principal cells: 335.6;Loop of henle epithelial cells: 340.7;Papillary tip epithelial cells: 181.5;Proximal tubule cells: 296.5;Renal collecting duct intercalated cells: 243.5;Renal collecting duct principal cells: 537.7;Renal connecting tubule cells: 327.3" "Cell type enriched" "Detected in some" 6 "cerebellar inhibitory: 82.4" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 30.3;Kidney Renal Papillary Cell Carcinoma (TCGA): 68.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "Kidney cancer: 17.9;ovarian cancer: 5.4;Rhabdoid: 10.8;Uterine cancer: 8.5" "Group enriched" "Detected in some" 9 "cerebellum: 1.3;pons and medulla: 3.4" "Group enriched" "Detected in some" 6 "cerebellum: 5.2;medulla oblongata: 7.7;spinal cord: 6.9" "CAB013024, HPA047704, HPA070751" Enhanced Supported Nucleoplasm "Intracellular and membrane" "Developmental protein" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 43: Hindbrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 3 Nucleoplasm "CAB013024: , HPA047704: , HPA070751: " "unprognostic (5.51e-2)" "unprognostic (7.96e-2)" "potential prognostic favorable (6.48e-4)" "potential prognostic favorable (1.19e-4)" "unprognostic (1.37e-2)" "unprognostic (7.08e-2)" "unprognostic (2.07e-2)" "unprognostic (5.85e-2)" "unprognostic (8.76e-2)" "unprognostic (4.67e-2)" PAX3 "HUP2, PAX-3, WS1" ENSG00000135903 "Paired box 3" P23760 2 222199887-222298998 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Myogenesis, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Deafness, Disease variant, Proto-oncogene, Waardenburg syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.7;salivary gland: 4.2;skeletal muscle: 3.4;skin 1: 2.7" "Group enriched" "Detected in some" 7 "Bergmann glia: 663.4;Melanocytes: 374.3" "Cell type enriched" "Detected in some" 7 "Bergmann glia: 676.3" "Cancer enriched" "Detected in some" 23 "Skin Cutaneous Melanoma (TCGA): 49.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 9.9;Sarcoma: 8.3;skin cancer: 23.0" "Testis - Early spermatids, Testis - Late spermatids" "Group enriched" "Detected in some" 7 "cerebellum: 3.4;midbrain: 1.4;pons and medulla: 1.3" "Region enhanced" "Detected in many" "midbrain: 9.7" "HPA063659, HPA069000" Enhanced Nucleoplasm NA NA "Cluster 2: Non-specific - Mixed function" "Cluster 25: Non-specific - Transcription" "Cluster 69: Skin cancer - ECM organization" "Cluster 61: Schwann cells & Melanocytes - Mixed function" 14 Nucleoplasm "HPA063659: , HPA069000: " "unprognostic (2.48e-2)" "unprognostic (2.30e-3)" "unprognostic (4.15e-2)" PAX4 MODY9 ENSG00000106331 "Paired box 4" O43316 7 127610292-127618142 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Diabetes mellitus, Disease variant" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "Late spermatids: 19.7;Neuroendocrine cells: 43.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" PAX5 "BSAP, PAX-5" ENSG00000196092 "Paired box 5" Q02548 9 36833269-37034268 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Spermatogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "lymphoid tissue: 37.0" "Cell type enriched" "Detected in some" 18 "B-cells: 496.0" "Cell type enriched" "Detected in some" 4 "leukocyte: 16.1" "Cancer enhanced" "Detected in some" "Stomach Adenocarcinoma (TCGA): 3.5" "Region enhanced" "Detected in many" "midbrain: 14.3" "Group enriched" "Detected in some" 44 "memory B-cell: 39.3;naive B-cell: 26.2" "Lineage enriched" "Detected in single" 53 "B-cells: 39.3" "Group enriched" "Detected in some" 11 "Leukemia: 33.8;lymphoma: 81.4" "Lung - B-cells (Lung), Skin - Outer root sheath cells, Spleen - B-cells (Spleen)" "Region enriched" "Detected in single" 11 "midbrain: 3.9" "Low region specificity" "Detected in all" "CAB026269, CAB026869, HPA056394" Enhanced Supported Supported Nucleoplasm NA NA "Cluster 34: B-cells - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 6: Leukemia - Signal transduction" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 38 Nucleoplasm "CAB026269: , CAB026869: , HPA056394: " "potential prognostic favorable (1.48e-5)" "unprognostic (2.72e-1)" "unprognostic (2.33e-3)" "unprognostic (2.14e-1)" "unprognostic (4.67e-2)" "unprognostic (1.56e-1)" "unprognostic (4.14e-2)" "unprognostic (2.18e-1)" "unprognostic (1.82e-1)" PAX6 "AN, AN1, AN2, D11S812E, WAGR" ENSG00000007372 "Paired box 6" P26367 11 31784779-31817961 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Disease variant, Peters anomaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 80.4;retina: 63.9" "Cell type enhanced" "Detected in some" "Astrocytes: 90.7;Bergmann glia: 114.0;Lacrimal acinar cells: 295.3;Müller glia: 477.0;Ocular epithelial cells: 417.7;Pancreatic islet cells: 618.8;Retinal amacrine cells: 493.4;Retinal ganglion cells: 220.2;Retinal horizontal cells: 232.4" "Group enriched" "Detected in many" 4 "astrocyte: 89.5;Bergmann glia: 113.2;ependymal cell: 44.3;upper rhombic lip: 135.0" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 15.7" "Region enhanced" "Detected in all" "cerebellum: 96.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Pancreas - Alpha cells, Pancreas - Beta cells, Stomach - Gastric enteroendocrine cells, Testis - Spermatocytes" "Region enhanced" "Detected in all" "cerebellum: 54.3" "Low region specificity" "Detected in all" "HPA030775, CAB034143" Enhanced Supported Enhanced Nucleoplasm NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 35: Non-specific - DNA binding" "Cluster 5: Rhabdoid - Unknown function" "Cluster 100: Stratified epithelial cells - Barrier functions" 98 Nucleoplasm "CAB034143: , HPA030775: " "unprognostic (6.80e-2)" "unprognostic (1.55e-2)" "unprognostic (4.16e-1)" "unprognostic (2.55e-2)" "unprognostic (6.80e-2)" "unprognostic (4.58e-1)" "unprognostic (2.38e-1)" "unprognostic (3.65e-3)" "unprognostic (7.49e-2)" "unprognostic (2.12e-1)" "unprognostic (1.59e-1)" "unprognostic (1.04e-1)" "unprognostic (1.80e-2)" "unprognostic (3.91e-3)" "unprognostic (1.64e-2)" "unprognostic (3.53e-2)" "unprognostic (3.71e-2)" "unprognostic (1.57e-1)" "unprognostic (2.34e-1)" PAX7 Hup1 ENSG00000009709 "Paired box 7" P23759 1 18630846-18748866 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Myogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "skeletal muscle: 5.3;tongue: 4.1" "Cell type enriched" "Detected in some" 39 "Myosatellite cells: 927.7" "Cell type enhanced" "Detected in some" "ependymal cell: 5.5" "Cancer enhanced" "Detected in some" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 3.1;Lung Adenocarcinoma (TCGA): 2.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 9 "Bone cancer: 52.8" "Region enriched" "Detected in single" 17 "midbrain: 4.6" "Region enhanced" "Detected in many" "thalamus: 5.6" NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 43: Hindbrain - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 7 "unprognostic (3.98e-1)" "unprognostic (1.28e-1)" "unprognostic (3.46e-2)" "unprognostic (1.10e-1)" PAX8 PAX-8 ENSG00000125618 "Paired box 8" Q06710 2 113215997-113278921 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "kidney: 241.1;thyroid gland: 537.2" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 1013.6;Endometrial luminal cells: 781.4;Endometrial secretory cells: 400.6;Epicardial cells: 1173.5;Loop of henle epithelial cells: 1370.5;Papillary tip epithelial cells: 724.0;Proximal tubule cells: 1331.6;Renal collecting duct intercalated cells: 1085.2;Renal collecting duct principal cells: 1496.4;Renal connecting tubule cells: 1024.4" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Thyroid Carcinoma (TCGA): 344.3" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 6 "Kidney cancer: 107.3;ovarian cancer: 135.6;Sarcoma: 61.2;thyroid cancer: 75.1;Uterine cancer: 158.2" "Region enriched" "Detected in some" 4 "pons and medulla: 5.5" "HPA030062, CAB055097, CAB061888, HPA064554" Enhanced Enhanced Nucleoplasm NA NA "Cluster 18: Non-specific - Translation" "Cluster 33: Thyroid gland - Tissue development" "Cluster 43: Hindbrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 51: Secretory epithelial cells - Mixed function" 16 Nucleoplasm "CAB055097: , CAB061888: , HPA030062: , HPA064554: " "potential prognostic unfavorable (5.27e-5)" "unprognostic (1.27e-2)" "unprognostic (1.03e-2)" "unprognostic (3.08e-1)" "unprognostic (2.13e-1)" "unprognostic (7.27e-2)" "unprognostic (1.66e-2)" "unprognostic (1.11e-3)" "unprognostic (2.92e-3)" "unprognostic (2.19e-1)" "unprognostic (6.38e-2)" "unprognostic (4.20e-3)" "unprognostic (4.23e-3)" "unprognostic (9.68e-3)" "unprognostic (6.82e-2)" "unprognostic (1.35e-1)" "unprognostic (4.02e-3)" "unprognostic (5.50e-2)" "unprognostic (1.02e-1)" "unprognostic (2.23e-2)" "unprognostic (7.11e-2)" "unprognostic (1.82e-3)" "unprognostic (1.57e-1)" "unprognostic (7.95e-2)" "unprognostic (1.52e-1)" "unprognostic (3.39e-1)" "unprognostic (1.56e-1)" "unprognostic (2.50e-1)" "unprognostic (4.03e-3)" "unprognostic (2.66e-1)" PAX9 ENSG00000198807 "Paired box 9" P55771 14 36657568-36679362 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 76.7;parathyroid gland: 40.5;salivary gland: 48.8" "Cell type enriched" "Detected in some" 5 "Esophageal apical cells: 1282.1" "Cell type enhanced" "Detected in single" "fibroblast: 1.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 21.5" "Colon - Enteric glia cells, Lung - Respiratory ciliated cells, Pituitary gland - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA001572, CAB016239" Enhanced Supported Nucleoplasm,Nucleoli NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 84: Apical squamous epithelium - Cornification" 23 Nucleoli Nucleoplasm "CAB016239: , HPA001572: " "unprognostic (1.36e-1)" "unprognostic (2.87e-1)" "unprognostic (1.27e-1)" "unprognostic (5.33e-2)" "unprognostic (2.14e-1)" "unprognostic (1.71e-2)" "unprognostic (4.07e-2)" "unprognostic (2.77e-1)" "unprognostic (2.52e-2)" "unprognostic (2.11e-3)" "unprognostic (1.04e-1)" "unprognostic (1.54e-1)" "unprognostic (1.15e-1)" "unprognostic (5.66e-3)" "unprognostic (1.87e-1)" "unprognostic (1.63e-1)" "unprognostic (4.13e-2)" PAXBP1 "C21orf66, fSAP105, GCFC, GCFC1" ENSG00000159086 "PAX3 and PAX7 binding protein 1" Q9Y5B6 21 32733899-32771792 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Myogenesis, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 255.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003757 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 56: Non-specific - Sensory perception" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 17 Nucleoplasm Cytosol "HPA003757: " "unprognostic (1.09e-1)" "unprognostic (1.23e-3)" "unprognostic (2.37e-1)" "unprognostic (1.41e-1)" "unprognostic (8.08e-2)" "unprognostic (1.20e-1)" "unprognostic (3.02e-2)" "unprognostic (1.24e-2)" "unprognostic (3.57e-3)" "unprognostic (2.55e-2)" "potential prognostic favorable (5.96e-5)" "unprognostic (1.00e-1)" "potential prognostic unfavorable (9.15e-4)" "unprognostic (3.56e-2)" "unprognostic (2.78e-2)" "unprognostic (8.73e-2)" "unprognostic (2.67e-3)" "unprognostic (4.43e-2)" "unprognostic (9.70e-2)" "unprognostic (3.07e-2)" "unprognostic (1.52e-2)" "unprognostic (7.40e-3)" "unprognostic (4.16e-3)" "unprognostic (1.89e-2)" "unprognostic (1.83e-1)" "unprognostic (2.98e-1)" "unprognostic (2.55e-1)" "unprognostic (1.76e-1)" "unprognostic (2.57e-1)" PAXIP1 "CAGF28, CAGF29, PAXIP1L, PTIP, TNRC2" ENSG00000157212 "PAX interacting protein 1" Q6ZW49 7 154943687-155003124 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 24.8" "Cell type enhanced" "Detected in many" "Epicardial cells: 72.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 9 "cerebellum: 21.7" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006694, HPA016950" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 61: Non-specific - Transcription" "Cluster 35: Non-specific - DNA binding" "Cluster 39: Non-specific - Transcription" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 56 "Nucleoplasm, Vesicles" "HPA006694: , HPA016950: " "unprognostic (1.01e-1)" "unprognostic (8.41e-2)" "unprognostic (1.01e-1)" "unprognostic (1.56e-1)" "unprognostic (9.78e-2)" "unprognostic (8.69e-2)" "unprognostic (1.97e-1)" "unprognostic (4.77e-2)" "unprognostic (2.19e-2)" "unprognostic (1.50e-1)" "potential prognostic favorable (4.42e-6)" "unprognostic (4.16e-2)" "unprognostic (1.51e-1)" "unprognostic (1.90e-3)" "unprognostic (2.93e-3)" "unprognostic (2.36e-2)" "unprognostic (2.22e-2)" "unprognostic (7.21e-3)" "unprognostic (7.99e-2)" "unprognostic (1.27e-1)" "unprognostic (7.25e-2)" "unprognostic (3.02e-2)" "unprognostic (8.99e-2)" "unprognostic (1.30e-1)" "unprognostic (5.73e-2)" "unprognostic (2.31e-1)" "unprognostic (4.45e-2)" "unprognostic (1.19e-1)" "unprognostic (4.62e-1)" "unprognostic (2.23e-2)" "unprognostic (1.35e-1)" PAXX "C9orf142, XLS" ENSG00000148362 "PAXX non-homologous end joining factor" Q9BUH6 9 136992422-136993984 "Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 172.9;Extravillous trophoblasts: 245.6;Migrating cytotrophoblasts: 204.3;pDCs: 271.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045268 Uncertain Supported Nucleoplasm NA NA 45000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 10 Nucleoplasm "HPA045268: " "unprognostic (3.50e-2)" "unprognostic (4.10e-2)" "unprognostic (3.85e-2)" "unprognostic (8.35e-2)" "unprognostic (3.56e-3)" "unprognostic (3.15e-2)" "unprognostic (4.61e-3)" "unprognostic (3.59e-2)" "potential prognostic favorable (5.38e-4)" "potential prognostic unfavorable (5.28e-5)" "unprognostic (1.62e-2)" "unprognostic (3.38e-1)" "unprognostic (1.82e-3)" "unprognostic (6.76e-2)" "unprognostic (1.76e-1)" "unprognostic (3.53e-3)" "unprognostic (3.11e-1)" "unprognostic (5.28e-2)" "unprognostic (3.27e-3)" "unprognostic (3.69e-3)" "unprognostic (3.18e-1)" "unprognostic (3.89e-1)" "unprognostic (1.22e-1)" "unprognostic (1.15e-1)" "unprognostic (6.34e-3)" "unprognostic (3.99e-2)" "unprognostic (1.73e-1)" "unprognostic (3.32e-1)" "unprognostic (1.85e-1)" PBDC1 "CXorf26, MGC874" ENSG00000102390 "Polysaccharide biosynthesis domain containing 1" Q9BVG4 X 76173040-76178314 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal suprabasal cells: 144.9;Ocular epithelial cells: 130.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003155 Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA 5100 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 49: Non-specific - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 36: Non-specific - mRNA processing" "Cluster 100: Stratified epithelial cells - Barrier functions" 4 Nucleoplasm "Nucleoli, Cytosol" "HPA003155: " "unprognostic (2.08e-1)" "unprognostic (4.65e-3)" "unprognostic (2.11e-2)" "unprognostic (2.31e-1)" "unprognostic (4.13e-2)" "unprognostic (5.21e-1)" "unprognostic (4.92e-2)" "unprognostic (1.00e-2)" "unprognostic (7.46e-2)" "unprognostic (3.18e-2)" "unprognostic (3.56e-1)" "unprognostic (7.18e-3)" "potential prognostic unfavorable (4.15e-4)" "unprognostic (1.03e-2)" "unprognostic (1.66e-3)" "unprognostic (4.85e-3)" "unprognostic (1.69e-1)" "unprognostic (1.82e-1)" "unprognostic (3.19e-1)" "unprognostic (2.22e-2)" "unprognostic (6.12e-2)" "unprognostic (2.72e-1)" "unprognostic (1.82e-1)" "unprognostic (1.02e-1)" "unprognostic (1.76e-2)" "unprognostic (5.86e-2)" "unprognostic (2.84e-1)" "unprognostic (5.10e-3)" "unprognostic (2.46e-1)" PBK "CT84, FLJ14385, Nori-3, SPK, TOPK" ENSG00000168078 "PDZ binding kinase" Q96KB5 8 27809624-27838082 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "lymphoid tissue: 21.3;testis: 65.7" "Group enriched" "Detected in many" 5 "Early spermatids: 308.2;Late primary spermatocytes: 988.4" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Thyroid gland - Mitotic cells (Thyroid)" "Group enriched" "Detected in many" 4 "basal ganglia: 4.7;white matter: 13.9" "Not detected" "Not detected" "HPA005753, HPA050656" Enhanced Supported Approved Cytosol NA Yes "Cluster 9: T-regs - Cell cycle regulation" "Cluster 39: Testis - Nuclear processes" "Cluster 40: Non-specific - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 44 Cytosol "HPA005753: , HPA050656: " "unprognostic (1.64e-1)" "unprognostic (8.31e-2)" "unprognostic (2.28e-1)" "unprognostic (6.88e-3)" "potential prognostic favorable (6.32e-4)" "unprognostic (2.19e-1)" "unprognostic (2.20e-2)" "unprognostic (2.13e-2)" "unprognostic (6.20e-2)" "potential prognostic unfavorable (1.21e-6)" "unprognostic (2.50e-3)" "potential prognostic unfavorable (1.39e-4)" "potential prognostic unfavorable (1.47e-6)" "validated prognostic unfavorable (7.03e-6)" "validated prognostic unfavorable (3.97e-6)" "potential prognostic unfavorable (2.67e-5)" "unprognostic (1.85e-2)" "unprognostic (2.20e-3)" "unprognostic (2.79e-2)" "unprognostic (2.45e-2)" "unprognostic (2.97e-1)" "potential prognostic unfavorable (3.76e-5)" "unprognostic (5.41e-2)" "unprognostic (1.16e-1)" "unprognostic (3.50e-2)" "unprognostic (2.34e-2)" "unprognostic (1.50e-1)" "unprognostic (4.13e-2)" "unprognostic (1.69e-1)" "unprognostic (2.73e-2)" PBLD "FLJ14767, MAWBP, MAWDBP" ENSG00000108187 "Phenazine biosynthesis like protein domain containing" P30039 10 68282660-68333049 "Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "intestine: 160.8;kidney: 251.7;liver: 312.7" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 124.5;Colonocytes: 99.4;Enterocytes: 395.6;Epicardial cells: 138.7;Epididymal efferent duct absorptive cells: 127.6;Gastric chief cells: 99.4;Hepatocytes: 270.8;Parietal cells: 178.6;Proximal tubule cells: 123.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Stomach - Parietal cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA038035, HPA038036" Enhanced Approved Vesicles NA NA 1300000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 76: Non-specific - Metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 56: Non-specific - Sensory perception" "Cluster 1: Enterocytes - Absorption and Digestion" 14 Vesicles "HPA038035: , HPA038036: " "unprognostic (5.49e-2)" "unprognostic (6.81e-2)" "unprognostic (4.01e-1)" "unprognostic (2.70e-2)" "unprognostic (4.30e-2)" "unprognostic (4.80e-2)" "unprognostic (1.02e-1)" "unprognostic (8.38e-3)" "unprognostic (8.12e-2)" "unprognostic (1.13e-1)" "validated prognostic favorable (9.92e-8)" "validated prognostic favorable (6.10e-4)" "unprognostic (2.27e-3)" "potential prognostic favorable (2.62e-4)" "unprognostic (1.61e-2)" "unprognostic (3.07e-1)" "unprognostic (2.42e-1)" "unprognostic (2.51e-2)" "unprognostic (8.17e-2)" "unprognostic (2.61e-2)" "unprognostic (1.86e-1)" "unprognostic (1.90e-1)" "unprognostic (3.43e-3)" "potential prognostic unfavorable (3.85e-4)" "unprognostic (1.17e-2)" "unprognostic (4.38e-2)" "unprognostic (2.99e-1)" "unprognostic (4.05e-1)" "unprognostic (3.37e-1)" "unprognostic (4.11e-2)" "unprognostic (2.61e-2)" PBOV1 "UC28, UROC28" ENSG00000254440 "Prostate and breast cancer overexpressed 1" Q9GZY1 6 138215986-138218491 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 54 "Epicardial cells: 36.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA063021, HPA069649" Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" Nucleoplasm Cytosol "HPA063021: , HPA069649: " "unprognostic (1.81e-1)" "unprognostic (1.02e-1)" PBRM1 "BAF180, PB1, SMARCH1" ENSG00000163939 "Polybromo 1" Q86U86 3 52545352-52685917 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015629, HPA059373" Uncertain Enhanced Nucleoplasm NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Transcription" 36 Nucleoplasm "HPA015629: , HPA059373: " "unprognostic (7.51e-3)" "unprognostic (1.60e-1)" "unprognostic (7.01e-2)" "unprognostic (6.06e-2)" "unprognostic (1.77e-1)" "unprognostic (1.94e-1)" "unprognostic (8.45e-2)" "unprognostic (2.81e-2)" "unprognostic (6.75e-3)" "unprognostic (1.07e-2)" "potential prognostic favorable (2.75e-5)" "unprognostic (2.08e-2)" "unprognostic (1.16e-1)" "unprognostic (2.78e-3)" "unprognostic (5.08e-2)" "unprognostic (6.94e-2)" "unprognostic (1.05e-1)" "unprognostic (1.21e-1)" "unprognostic (2.30e-1)" "unprognostic (1.40e-1)" "unprognostic (3.92e-3)" "unprognostic (6.22e-2)" "unprognostic (1.14e-1)" "unprognostic (1.26e-1)" "unprognostic (4.57e-3)" "unprognostic (8.94e-2)" "unprognostic (6.36e-2)" "unprognostic (1.24e-1)" "unprognostic (2.86e-1)" "unprognostic (1.40e-2)" "unprognostic (1.81e-1)" PBX1 ENSG00000185630 "PBX homeobox 1" P40424 1 164555584-164899296 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Sexual differentiation, Steroidogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pituitary stem cells: 1944.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003505, HPA003881, CAB018768" Supported Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 14: Neurons - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 105: Non-specific - Mixed function" 30 Nucleoplasm "Nuclear bodies, Cytosol" "CAB018768: , HPA003505: , HPA003881: " "potential prognostic favorable (7.04e-5)" "unprognostic (1.34e-2)" "unprognostic (1.08e-1)" "unprognostic (1.31e-1)" "unprognostic (1.59e-1)" "unprognostic (1.30e-1)" "unprognostic (1.44e-2)" "unprognostic (1.70e-1)" "unprognostic (5.22e-3)" "unprognostic (1.01e-2)" "validated prognostic favorable (1.08e-5)" "validated prognostic favorable (5.97e-5)" "unprognostic (8.21e-3)" "unprognostic (1.52e-1)" "unprognostic (6.65e-2)" "unprognostic (4.58e-1)" "unprognostic (1.71e-1)" "unprognostic (1.06e-1)" "unprognostic (4.53e-2)" "unprognostic (1.60e-1)" "unprognostic (1.86e-1)" "unprognostic (1.53e-1)" "unprognostic (1.04e-1)" "unprognostic (2.27e-1)" "unprognostic (2.35e-1)" "unprognostic (2.03e-1)" "unprognostic (1.21e-1)" "unprognostic (1.15e-1)" "unprognostic (5.47e-2)" "unprognostic (1.33e-1)" "unprognostic (1.69e-1)" PBX2 "G17, HOX12, PBX2MHC" ENSG00000204304 "PBX homeobox 2" P40425 6 32184733-32190202 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 21.4;Bergmann glia: 23.0;Distal convoluted tubule cells: 14.8;Ependymal cells: 13.0;Loop of henle epithelial cells: 16.2;Microglia: 23.6;Oligodendrocyte progenitor cells: 13.5;Oligodendrocytes: 12.7;Papillary tip epithelial cells: 14.8;Podocytes: 47.0;Proximal tubule cells: 15.1;Renal collecting duct intercalated cells: 13.3;Renal collecting duct principal cells: 16.0;Renal connecting tubule cells: 15.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061478 Supported Supported Nucleoplasm NA NA "Cluster 64: Non-specific - Transcription" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 28: Non-specific - Nuclear processes" "Cluster 102: Non-specific - Mixed function" 26 Nucleoplasm "HPA061478: " "unprognostic (1.94e-2)" "unprognostic (2.49e-1)" "unprognostic (1.06e-2)" "unprognostic (5.90e-2)" "unprognostic (2.22e-1)" "unprognostic (4.59e-2)" "unprognostic (1.41e-2)" "unprognostic (1.00e-1)" "unprognostic (3.24e-1)" "unprognostic (2.40e-1)" "unprognostic (2.73e-1)" "unprognostic (1.24e-1)" "unprognostic (7.10e-3)" "unprognostic (1.33e-1)" "unprognostic (8.44e-2)" "unprognostic (5.37e-2)" "unprognostic (1.44e-1)" "unprognostic (1.16e-1)" "unprognostic (7.40e-3)" "unprognostic (1.32e-1)" "unprognostic (1.87e-1)" "unprognostic (2.02e-1)" "unprognostic (2.03e-3)" "unprognostic (1.32e-1)" "unprognostic (4.41e-2)" "unprognostic (5.71e-2)" "unprognostic (1.52e-1)" "unprognostic (3.11e-1)" "unprognostic (1.37e-1)" "unprognostic (8.49e-2)" "unprognostic (1.78e-1)" PBX3 ENSG00000167081 "PBX homeobox 3" P40426 9 125747345-125967377 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 144.0" "Cell type enhanced" "Detected in all" "Adrenal cortex cells: 709.4;Cone photoreceptor cells: 507.2" "Cell type enhanced" "Detected in all" "eccentric medium spiny neuron: 1632.7" "Cancer enhanced" "Detected in all" "Thyroid Carcinoma (TCGA): 93.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "plasmacytoid DC: 14.0" "Lineage enriched" "Detected in all" 4 "dendritic cells: 14.0" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts" "Region enhanced" "Detected in all" "olfactory bulb: 167.4" "Group enriched" "Detected in all" 5 "basal ganglia: 56.8;olfactory bulb: 199.8" HPA003881 Supported Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 18: Adrenal cortex cells - Steroidogensis" 1 Nucleoplasm "Nuclear bodies, Cytosol" "HPA003881: " "unprognostic (6.00e-2)" "unprognostic (1.19e-1)" "unprognostic (1.14e-1)" "unprognostic (8.18e-2)" "unprognostic (1.19e-2)" "unprognostic (3.85e-3)" "unprognostic (2.87e-1)" "unprognostic (7.10e-2)" "unprognostic (1.05e-1)" "unprognostic (1.26e-1)" "unprognostic (2.06e-3)" "unprognostic (1.59e-1)" "unprognostic (6.05e-2)" "unprognostic (1.55e-1)" "unprognostic (1.74e-1)" "unprognostic (1.80e-1)" "unprognostic (1.62e-2)" "unprognostic (4.64e-3)" "unprognostic (1.18e-1)" "unprognostic (1.51e-1)" "unprognostic (2.72e-2)" "unprognostic (1.62e-2)" "unprognostic (1.73e-1)" "unprognostic (5.62e-2)" "unprognostic (1.05e-2)" "unprognostic (8.45e-2)" "unprognostic (1.84e-1)" "unprognostic (2.15e-2)" "unprognostic (3.27e-1)" "unprognostic (9.33e-2)" "unprognostic (1.10e-1)" PBX4 ENSG00000105717 "PBX homeobox 4" Q9BYU1 19 19561707-19618693 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 3.5;thyroid gland: 3.6" "Cell type enriched" "Detected in many" 4 "T-cells: 336.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 7 "gdT-cell: 1.7;MAIT T-cell: 1.7;memory CD4 T-cell: 1.2;memory CD8 T-cell: 1.9;naive CD4 T-cell: 1.2;naive CD8 T-cell: 1.0;T-reg: 3.1" "Lineage enriched" "Detected in single" 12 "T-cells: 3.1" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 4.1" "Adipose visceral - T-cells, Adrenal gland - T-cells, Minor Salivary Gland - T-cells, Stomach - Gastric mucous cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA049859, HPA056469" Enhanced Approved Vesicles NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 67: Testis - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 9: T-cells - Adaptive immunity: Regulation" 69 Vesicles "HPA049859: , HPA056469: " "unprognostic (1.45e-1)" "unprognostic (1.14e-1)" "unprognostic (8.64e-3)" "unprognostic (6.47e-3)" "unprognostic (1.39e-2)" "unprognostic (1.11e-1)" "unprognostic (6.88e-3)" PBXIP1 HPIP ENSG00000163346 "PBX homeobox interacting protein 1" Q96AQ6 1 154944076-154956123 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 672.0" "Cell type enhanced" "Detected in many" "Early spermatids: 160.0;Late spermatids: 280.9;Müller glia: 220.5;Smooth muscle cells: 169.6;Tuft cells: 415.0" "Cell type enhanced" "Detected in many" "astrocyte: 119.8;choroid plexus epithelial cell: 108.0;ependymal cell: 85.0;leukocyte: 75.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "granulocytes: 184.2;NK-cells: 57.0;T-cells: 197.9" "Cancer enhanced" "Detected in all" "Myeloma: 188.5" "Adipose subcutaneous - Smooth muscle cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006949, HPA073481" Approved Supported Nucleoplasm,Cytosol NA NA 44000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 44: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 9: T-cells - Adaptive immunity: Regulation" 27 Nucleoplasm Cytosol "HPA006949: , HPA073481: " "unprognostic (3.45e-3)" "unprognostic (1.89e-1)" "unprognostic (3.86e-2)" "unprognostic (2.09e-1)" "unprognostic (1.46e-1)" "unprognostic (1.67e-1)" "unprognostic (1.61e-1)" "unprognostic (3.66e-2)" "unprognostic (2.82e-2)" "unprognostic (8.16e-2)" "potential prognostic favorable (2.30e-9)" "unprognostic (3.06e-3)" "unprognostic (6.14e-3)" "unprognostic (7.02e-2)" "unprognostic (2.21e-2)" "unprognostic (2.08e-3)" "unprognostic (5.04e-3)" "unprognostic (1.52e-1)" "unprognostic (3.48e-1)" "unprognostic (3.66e-1)" "unprognostic (1.59e-2)" "unprognostic (1.20e-3)" "unprognostic (1.40e-3)" "unprognostic (3.61e-2)" "unprognostic (1.79e-2)" "unprognostic (2.03e-2)" "unprognostic (2.43e-1)" "unprognostic (1.82e-1)" "unprognostic (1.43e-1)" "unprognostic (2.44e-1)" "unprognostic (3.78e-1)" PC PCB ENSG00000173599 "Pyruvate carboxylase" P11498 11 66848417-66958386 "Citric acid cycle related proteins, Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Gluconeogenesis, Lipid biosynthesis, Lipid metabolism" "Ligase, Multifunctional enzyme" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 182.1" "Cell type enhanced" "Detected in many" "Adipocytes: 252.6;Hepatocytes: 250.1;Lacrimal acinar cells: 97.8;Late spermatids: 89.6;Proximal tubule cells: 104.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 63.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Stomach - Chief cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033742, HPA043922, HPA058765, HPA070392" Enhanced Enhanced Mitochondria Yes No 180000 "Cluster 13: Non-specific - Mitochondria" "Cluster 36: Brain & Liver - Signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 89: Adipocytes - Lipid metabolism" 14 Mitochondria "CAB033742: , HPA043922: , HPA058765: , HPA070392: " "unprognostic (1.41e-2)" "unprognostic (1.71e-1)" "unprognostic (1.11e-2)" "unprognostic (1.64e-2)" "potential prognostic favorable (8.68e-4)" "unprognostic (3.58e-2)" "unprognostic (3.44e-1)" "unprognostic (4.42e-3)" "unprognostic (1.13e-1)" "unprognostic (1.71e-2)" "potential prognostic favorable (6.67e-7)" "unprognostic (2.27e-1)" "unprognostic (2.24e-3)" "unprognostic (3.24e-1)" "unprognostic (7.21e-3)" "unprognostic (1.18e-1)" "unprognostic (3.38e-3)" "unprognostic (6.52e-2)" "unprognostic (3.78e-2)" "potential prognostic unfavorable (5.97e-4)" "unprognostic (1.67e-1)" "unprognostic (1.49e-1)" "unprognostic (3.06e-2)" "unprognostic (8.20e-2)" "unprognostic (8.91e-2)" "unprognostic (2.21e-1)" "unprognostic (5.13e-1)" "unprognostic (5.21e-2)" "unprognostic (4.11e-1)" "unprognostic (1.66e-2)" "unprognostic (1.23e-3)" PCARE "C2orf71, FLJ34931, RP54" ENSG00000179270 "Photoreceptor cilium actin regulator" A6NGG8 2 29060976-29074523 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Ciliopathy, Cone-rod dystrophy, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 45 "retina: 26.4" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 39.3;Early spermatids: 9.6;Late spermatids: 5.3;Oocytes: 9.2;Podocytes: 5.9;Rod photoreceptor cells: 44.0;Thymic myoid cells: 27.2" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 2.4;MGE interneuron: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Kidney - Podocytes, Skin - Outer root sheath cells, Testis - Late spermatids" "Not detected" "Not detected" "Region enhanced" "Detected in single" "medulla oblongata: 1.1" NA NA "Cluster 42: Retina - Visual perception" "Cluster 36: Choroid plexus - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 79: Photoreceptor cells - Phototransduction" 5 PCBD1 "DCOH, PCBD, PCD" ENSG00000166228 "Pterin-4 alpha-carbinolamine dehydratase 1" P61457 10 70882280-70888565 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Tetrahydrobiopterin biosynthesis, Transcription, Transcription regulation" "Activator, Lyase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 488.2" "Cell type enhanced" "Detected in many" "Epididymal efferent duct absorptive cells: 416.2;Gastric progenitor cells: 325.5;Hepatocytes: 604.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037575, HPA061723" Enhanced Enhanced Nucleoplasm,Cytosol NA NA 540000 "Cluster 13: Non-specific - Mitochondria" "Cluster 76: Non-specific - Metabolism" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 52: Non-specific - Mitochondria" "Cluster 97: Non-specific - Cellular respiration" 26 Nucleoplasm Cytosol "HPA037575: , HPA061723: " "unprognostic (6.80e-3)" "unprognostic (2.35e-2)" "unprognostic (3.68e-1)" "unprognostic (6.28e-3)" "unprognostic (1.50e-1)" "unprognostic (1.18e-2)" "unprognostic (5.59e-3)" "unprognostic (3.19e-1)" "unprognostic (1.96e-2)" "unprognostic (5.59e-2)" "unprognostic (3.69e-2)" "unprognostic (9.65e-3)" "unprognostic (6.90e-3)" "unprognostic (1.04e-1)" "unprognostic (4.74e-2)" "unprognostic (1.84e-1)" "unprognostic (8.32e-2)" "unprognostic (4.15e-2)" "unprognostic (3.35e-2)" "unprognostic (1.56e-1)" "unprognostic (2.03e-1)" "unprognostic (1.47e-1)" "unprognostic (2.82e-1)" "unprognostic (3.72e-2)" "unprognostic (1.72e-1)" "unprognostic (1.65e-2)" "unprognostic (1.43e-1)" "unprognostic (4.36e-2)" "unprognostic (1.90e-1)" "unprognostic (5.17e-2)" "unprognostic (4.60e-2)" PCBD2 "DCOH2, DCOHM" ENSG00000132570 "Pterin-4 alpha-carbinolamine dehydratase 2" Q9H0N5 5 134905120-135007959 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Tetrahydrobiopterin biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 46.2;tongue: 40.0" "Cell type enhanced" "Detected in many" "Myonuclei: 254.5" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 135.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036428 Uncertain Approved "Plasma membrane" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 52: Non-specific - Cellular respiration" "Cluster 6: Non-specific - Immune response" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 15 "Plasma membrane" "HPA036428: " "unprognostic (9.21e-2)" "unprognostic (7.27e-3)" "unprognostic (3.16e-1)" "unprognostic (3.06e-1)" "unprognostic (1.99e-1)" "unprognostic (5.04e-2)" "unprognostic (2.54e-1)" "unprognostic (6.55e-2)" "unprognostic (6.21e-2)" "unprognostic (1.55e-1)" "potential prognostic favorable (2.16e-4)" "unprognostic (2.74e-2)" "potential prognostic favorable (1.16e-5)" "unprognostic (2.66e-1)" "unprognostic (9.84e-2)" "unprognostic (8.39e-2)" "unprognostic (2.72e-1)" "unprognostic (1.25e-2)" "unprognostic (1.03e-1)" "unprognostic (1.92e-1)" "unprognostic (2.88e-1)" "unprognostic (1.79e-1)" "unprognostic (2.69e-2)" "unprognostic (1.25e-1)" "unprognostic (7.66e-2)" "unprognostic (4.16e-1)" "unprognostic (8.85e-2)" "unprognostic (3.29e-1)" "unprognostic (9.76e-2)" "unprognostic (3.42e-2)" "unprognostic (2.70e-1)" PCBP1 "hnRNP-E1, hnRNP-X, HNRPE1, HNRPX" ENSG00000169564 "Poly(rC) binding protein 1" Q15365 2 70087477-70089203 "Cancer-related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Viral RNA replication" "DNA-binding, Ribonucleoprotein, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1253.8;Syncytiotrophoblasts: 804.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037113, HPA043803, HPA068497" Approved Supported "Nucleoplasm,Nuclear speckles,Cytosol,Cytoplasmic bodies" No No 2700000 "Cluster 45: Eosinophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 111 "Nuclear speckles" "Nucleoplasm, Cytosol, Cytoplasmic bodies" "CAB037113: , HPA043803: , HPA068497: " "unprognostic (2.51e-1)" "unprognostic (1.56e-1)" "unprognostic (1.18e-1)" "unprognostic (2.20e-2)" "unprognostic (2.15e-1)" "unprognostic (2.98e-1)" "unprognostic (1.83e-1)" "potential prognostic unfavorable (9.99e-4)" "unprognostic (1.09e-2)" "unprognostic (3.37e-1)" "potential prognostic favorable (1.48e-9)" "unprognostic (1.51e-3)" "unprognostic (1.02e-1)" "unprognostic (6.47e-3)" "unprognostic (6.82e-3)" "potential prognostic unfavorable (7.88e-4)" "unprognostic (8.52e-2)" "unprognostic (7.72e-2)" "unprognostic (1.88e-2)" "unprognostic (1.36e-1)" "unprognostic (1.97e-2)" "unprognostic (2.21e-2)" "unprognostic (4.36e-3)" "unprognostic (1.17e-1)" "unprognostic (2.18e-1)" "unprognostic (1.08e-1)" "unprognostic (1.48e-1)" "unprognostic (1.68e-1)" "unprognostic (4.18e-1)" "unprognostic (1.05e-1)" "unprognostic (2.67e-1)" PCBP2 "hnRNP-E2, HNRNPE2, HNRPE2" ENSG00000197111 "Poly(rC) binding protein 2" Q15366 12 53452102-53481162 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity, Viral RNA replication" "DNA-binding, Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038356, HPA073145" Approved Supported Nucleoplasm,Cytosol NA NA 1300000 "Cluster 30: Non-specific - DNA binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 44 "Nucleoplasm, Cytosol" "HPA038356: , HPA073145: " "unprognostic (1.30e-2)" "unprognostic (6.46e-2)" "unprognostic (8.62e-2)" "unprognostic (6.48e-3)" "unprognostic (1.14e-1)" "unprognostic (7.67e-2)" "unprognostic (2.21e-1)" "unprognostic (3.59e-1)" "unprognostic (3.67e-3)" "unprognostic (1.76e-2)" "validated prognostic favorable (2.50e-7)" "validated prognostic favorable (6.63e-5)" "unprognostic (1.80e-1)" "validated prognostic unfavorable (3.83e-5)" "validated prognostic unfavorable (1.67e-5)" "potential prognostic unfavorable (9.47e-4)" "unprognostic (1.17e-2)" "unprognostic (2.14e-2)" "unprognostic (7.78e-2)" "unprognostic (1.57e-1)" "unprognostic (3.88e-1)" "unprognostic (7.89e-2)" "unprognostic (5.56e-2)" "unprognostic (2.53e-1)" "unprognostic (1.10e-1)" "unprognostic (4.56e-2)" "unprognostic (5.79e-2)" "unprognostic (1.43e-1)" "unprognostic (1.41e-1)" "unprognostic (1.71e-2)" "unprognostic (7.77e-2)" PCBP3 "FLJ44028, PCBP3-OT1, PCBP3OT" ENSG00000183570 "Poly(rC) binding protein 3" P57721 21 45643694-45942454 "Plasma proteins, Predicted intracellular proteins" "DNA-binding, Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 59.3;retina: 75.7" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 1289.7;Corticotrophs: 568.8;Early primary spermatocytes: 415.8;Retinal amacrine cells: 402.2;Retinal bipolar cells: 741.8;Retinal ganglion cells: 633.5;Retinal horizontal cells: 414.7;Rod photoreceptor cells: 1187.2;Thymocytes: 418.4" "Cell type enhanced" "Detected in all" "midbrain-derived inhibitory: 1029.0;pericyte: 591.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 3.0" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Neuroblastoma: 37.3" "Adrenal gland - Adrenal medulla cells, Pituitary gland - Corticotropes, Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in all" 5 "olfactory bulb: 229.2" "Region enhanced" "Detected in all" "olfactory bulb: 111.2" "HPA030247, HPA073145" Approved Uncertain Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 41: Basophils - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 49: Hindbrain - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" 7 "Nucleoplasm, Mitochondria" Vesicles "HPA030247: , HPA073145: " "unprognostic (2.63e-2)" "unprognostic (2.08e-3)" "potential prognostic unfavorable (3.44e-4)" "unprognostic (2.02e-3)" "unprognostic (2.44e-1)" "unprognostic (1.28e-2)" "unprognostic (1.70e-1)" "unprognostic (6.47e-2)" "validated prognostic unfavorable (7.00e-7)" "validated prognostic unfavorable (8.45e-4)" "unprognostic (1.93e-3)" "unprognostic (1.90e-2)" "unprognostic (6.11e-2)" "unprognostic (4.86e-3)" "unprognostic (1.22e-1)" "unprognostic (1.27e-3)" "potential prognostic favorable (2.99e-4)" "unprognostic (3.80e-1)" "unprognostic (4.04e-2)" "unprognostic (2.24e-2)" "unprognostic (1.65e-3)" "unprognostic (4.62e-2)" "unprognostic (3.61e-2)" "unprognostic (3.71e-2)" "unprognostic (4.27e-3)" PCBP4 "LIP4, MCG10" ENSG00000090097 "Poly(rC) binding protein 4" P57723 3 51957454-51974016 "Predicted intracellular proteins" "DNA-binding, Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 257.0;retina: 363.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 376.8;Late spermatids: 167.1;Oligodendrocyte progenitor cells: 69.2;Oligodendrocytes: 94.0;Retinal bipolar cells: 230.4;Retinal pigment epithelial cells: 72.5;Rod photoreceptor cells: 254.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 22 "B-cells: 5.2;granulocytes: 7.0;T-cells: 12.1" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057754 Supported Cytosol NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 11: White matter - Signal transduction" "Cluster 1: Neuronal - Visual perception" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 4 Cytosol "HPA057754: " "unprognostic (6.83e-2)" "unprognostic (2.60e-1)" "unprognostic (2.45e-1)" "unprognostic (2.92e-2)" "unprognostic (1.96e-1)" "unprognostic (1.82e-1)" "unprognostic (6.22e-3)" "unprognostic (1.96e-3)" "unprognostic (1.11e-1)" "potential prognostic unfavorable (2.19e-4)" "potential prognostic unfavorable (1.34e-4)" "unprognostic (3.46e-2)" "unprognostic (3.61e-2)" "unprognostic (1.45e-3)" "unprognostic (2.32e-2)" "unprognostic (4.63e-2)" "unprognostic (2.59e-2)" "unprognostic (2.68e-1)" "unprognostic (2.26e-1)" "unprognostic (1.37e-1)" "unprognostic (4.77e-1)" "unprognostic (2.31e-1)" "unprognostic (2.10e-1)" "unprognostic (5.25e-2)" "unprognostic (1.85e-1)" "unprognostic (1.36e-2)" "unprognostic (2.32e-1)" "unprognostic (1.60e-1)" "unprognostic (2.05e-1)" "unprognostic (2.23e-2)" "unprognostic (1.06e-1)" PCCA ENSG00000175198 "Propionyl-CoA carboxylase subunit alpha" P05165 13 100089015-100530437 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Ligase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 206.3" "Cell type enhanced" "Detected in all" "Choroid plexus epithelial cells: 837.4;Distal convoluted tubule cells: 879.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Spleen - Macrophages, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041716, HPA047792" Enhanced Supported Mitochondria NA NA 300000 "Cluster 33: Non-specific - ATP binding" "Cluster 22: Epididymis - Mixed function" "Cluster 25: Non-specific - Transcription" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 8 Mitochondria "HPA041716: , HPA047792: " "unprognostic (6.74e-2)" "unprognostic (8.69e-2)" "unprognostic (1.55e-1)" "unprognostic (1.03e-1)" "unprognostic (1.07e-2)" "unprognostic (9.14e-2)" "unprognostic (2.01e-2)" "unprognostic (3.25e-2)" "unprognostic (1.19e-1)" "unprognostic (5.54e-2)" "validated prognostic favorable (2.50e-9)" "validated prognostic favorable (1.02e-4)" "potential prognostic favorable (5.51e-8)" "unprognostic (2.01e-1)" "unprognostic (9.22e-3)" "unprognostic (5.30e-2)" "unprognostic (1.77e-1)" "unprognostic (6.48e-2)" "unprognostic (1.09e-1)" "unprognostic (1.29e-1)" "unprognostic (2.90e-2)" "unprognostic (1.13e-1)" "unprognostic (2.93e-1)" "unprognostic (2.15e-1)" "unprognostic (1.81e-1)" "unprognostic (4.96e-2)" "unprognostic (1.82e-2)" "unprognostic (3.41e-2)" "unprognostic (4.92e-3)" "unprognostic (1.59e-1)" "unprognostic (4.54e-3)" PCCB ENSG00000114054 "Propionyl-CoA carboxylase subunit beta" P05166 3 136250340-136337896 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Ligase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 188.7" "Cell type enhanced" "Detected in many" "Early spermatids: 499.9;Late spermatids: 206.5;Oocytes: 303.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036939, HPA036940" Enhanced NA NA 280000 "Cluster 13: Non-specific - Mitochondria" "Cluster 76: Non-specific - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 32 "HPA036939: , HPA036940: " "unprognostic (3.42e-1)" "unprognostic (9.48e-2)" "unprognostic (4.46e-2)" "unprognostic (8.34e-3)" "unprognostic (1.21e-2)" "unprognostic (4.10e-2)" "unprognostic (3.20e-2)" "unprognostic (5.87e-3)" "unprognostic (2.62e-1)" "potential prognostic unfavorable (2.60e-4)" "unprognostic (7.04e-2)" "unprognostic (2.30e-2)" "potential prognostic favorable (1.07e-4)" "unprognostic (5.97e-2)" "unprognostic (6.66e-3)" "unprognostic (5.10e-2)" "unprognostic (2.59e-1)" "unprognostic (6.61e-2)" "unprognostic (3.56e-2)" "unprognostic (1.17e-1)" "unprognostic (1.20e-1)" "unprognostic (9.45e-2)" "unprognostic (2.17e-3)" "unprognostic (1.33e-1)" "unprognostic (3.25e-1)" "unprognostic (3.58e-2)" "unprognostic (6.80e-3)" "unprognostic (6.07e-2)" "unprognostic (1.58e-1)" "unprognostic (1.83e-1)" "unprognostic (7.40e-2)" PCDH1 pc42 ENSG00000156453 "Protocadherin 1" Q08174 5 141853090-141879246 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 272.7;Foveolar cells: 65.5;Salivary duct cells: 80.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 76.0" "Kidney - Macrophages, Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Endothelial cells, Skin - Keratinocyte (granular), Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047720, HPA050538" Enhanced Approved "Nucleoplasm,Nucleoli,Cell Junctions" NA NA 3000000 "Cluster 11: Esophagus - Basic cellular processes" "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "Nucleoplasm, Cell Junctions" Nucleoli "HPA047720: , HPA050538: " "unprognostic (1.75e-1)" "unprognostic (1.98e-2)" "unprognostic (1.83e-1)" "unprognostic (2.83e-2)" "unprognostic (6.34e-2)" "unprognostic (5.67e-2)" "unprognostic (7.04e-2)" "unprognostic (1.06e-1)" "unprognostic (6.31e-2)" "unprognostic (2.25e-1)" "validated prognostic favorable (1.87e-6)" "validated prognostic favorable (2.56e-4)" "unprognostic (1.03e-3)" "validated prognostic unfavorable (2.07e-4)" "validated prognostic unfavorable (7.57e-4)" "unprognostic (4.91e-2)" "unprognostic (8.77e-2)" "potential prognostic unfavorable (2.51e-4)" "unprognostic (3.98e-3)" "unprognostic (2.09e-2)" "unprognostic (3.02e-2)" "potential prognostic unfavorable (4.25e-4)" "unprognostic (5.84e-2)" "unprognostic (3.50e-1)" "unprognostic (2.93e-1)" "potential prognostic unfavorable (2.09e-4)" "unprognostic (1.03e-1)" "unprognostic (1.67e-1)" "unprognostic (1.17e-1)" "unprognostic (3.57e-1)" "unprognostic (2.24e-1)" PCDH10 "KIAA1400, OL-PCDH" ENSG00000138650 "Protocadherin 10" Q9P2E7 4 133149294-133208606 "Predicted membrane proteins" "Cell adhesion" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "blood vessel: 19.1;brain: 35.0;placenta: 24.3;prostate: 10.0;seminal vesicle: 16.3" "Cell type enhanced" "Detected in many" "Astrocytes: 74.6;Brain excitatory neurons: 39.7;Brain inhibitory neurons: 108.7;Corticotrophs: 44.3;Endometrial luminal cells: 85.2;Epididymal efferent duct absorptive cells: 131.8;Epididymal efferent duct ciliated cells: 42.8;Oligodendrocyte progenitor cells: 69.0;Oligodendrocytes: 121.6;Other brain neurons: 79.4;Schwann cells: 41.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 18.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 44.4" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Adrenal gland - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011220, HPA073462" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" No NA 21000 "Cluster 73: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 35: Neurons - Synaptic function & neurogenesis" 7 "Golgi apparatus" "Nucleoplasm, Vesicles" "HPA011220: , HPA073462: " "unprognostic (1.96e-1)" "unprognostic (2.27e-1)" "unprognostic (1.65e-1)" "unprognostic (8.17e-2)" "unprognostic (2.42e-3)" "unprognostic (1.17e-2)" "unprognostic (4.77e-3)" "unprognostic (1.20e-1)" "unprognostic (5.48e-2)" "unprognostic (8.50e-2)" PCDH11X "PCDH-X, PCDH11, PCDHX, PPP1R119" ENSG00000102290 "Protocadherin 11 X-linked" Q9BZA7 X 91779261-92623230 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.8;ovary: 4.8" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 194.3;Brain inhibitory neurons: 645.5;Cytotrophoblasts: 410.4;Melanocytes: 197.4;Oligodendrocyte progenitor cells: 323.3;Oligodendrocytes: 121.6;Other brain neurons: 319.5;Pituitary stem cells: 401.7;Retinal horizontal cells: 376.6;Syncytiotrophoblasts: 277.3" "Cell type enhanced" "Detected in all" "eccentric medium spiny neuron: 3107.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Bone cancer: 1.3" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Adrenal gland - Adrenal medulla cells, Pituitary gland - Thyrotropes, Skin - Outer root sheath cells" "HPA000432, HPA077495" Approved Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 3: Rhabdoid - Membrane components" "Cluster 35: Neurons - Synaptic function & neurogenesis" 1 "Plasma membrane" "Vesicles, Cytosol" "HPA000432: , HPA077495: " "potential prognostic favorable (4.62e-4)" PCDH11Y "PCDH22, PCDHY" ENSG00000099715 "Protocadherin 11 Y-linked" Q9BZA8 Y 5000226-5742224 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 2.4" "Cell type enriched" "Detected in many" 4 "Retinal horizontal cells: 789.3" "Cell type enhanced" "Detected in many" "eccentric medium spiny neuron: 571.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 1.1;Rhabdoid: 1.8" HPA000432 Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 109: Neurons - Neuronal signaling" "Plasma membrane" "Vesicles, Cytosol" "HPA000432: " "potential prognostic favorable (7.46e-4)" "unprognostic (3.29e-2)" PCDH12 ENSG00000113555 "Protocadherin 12" Q9NPG4 5 141943581-141969741 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant, Epilepsy, Intellectual disability, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 28.4" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 119.0;Early spermatids: 16.4;Epicardial cells: 84.1;Hofbauer cells: 83.5;Kupffer cells: 27.7;Lymphatic endothelial cells: 40.2;Vascular endothelial cells: 32.8" "Group enriched" "Detected in many" 5 "central nervous system macrophage: 10.8;endothelial cell: 18.2" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 20.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "non-classical monocyte: 4.7" "Lineage enriched" "Detected in single" 41 "monocytes: 4.7" "Cancer enhanced" "Detected in some" "Myeloma: 3.4" "Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Prostate - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA051242 Uncertain "Secreted to blood" "Cell adhesion" NA NA 15000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 48: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "HPA051242: " "unprognostic (2.08e-1)" "unprognostic (2.20e-2)" "unprognostic (3.58e-1)" "unprognostic (7.48e-2)" "unprognostic (2.99e-2)" "unprognostic (1.19e-1)" "unprognostic (2.25e-1)" "unprognostic (4.47e-1)" "unprognostic (1.59e-1)" "unprognostic (1.17e-1)" "validated prognostic favorable (2.30e-7)" "validated prognostic favorable (2.81e-4)" "unprognostic (1.43e-3)" "unprognostic (1.62e-1)" "unprognostic (2.39e-3)" "unprognostic (2.18e-1)" "unprognostic (3.18e-3)" "potential prognostic unfavorable (9.57e-4)" "unprognostic (3.49e-1)" "unprognostic (1.33e-1)" "unprognostic (1.78e-2)" "unprognostic (5.75e-2)" "unprognostic (7.18e-2)" "unprognostic (1.70e-1)" "unprognostic (4.01e-2)" "unprognostic (2.23e-1)" "unprognostic (2.17e-2)" "unprognostic (8.08e-3)" "unprognostic (1.77e-1)" "unprognostic (4.56e-1)" "unprognostic (3.28e-1)" PCDH15 "CDHR15, DFNB23, USH1F" ENSG00000150275 "Protocadherin related 15" Q96QU1 10 53802771-55627942 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Hearing" "Deafness, Disease variant, Non-syndromic deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "adrenal gland: 17.9;retina: 57.2" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 1026.5;Cone photoreceptor cells: 1968.7;Lactotrophs: 1040.0;Oligodendrocyte progenitor cells: 4341.5;Pituicytes/FSCs: 3767.3;Proximal tubule cells: 650.3;Rod photoreceptor cells: 2705.9" "Cell type enhanced" "Detected in all" "oligodendrocyte precursor cell: 4937.3" "Cancer enriched" "Detected in some" 5 "Glioblastoma Multiforme (TCGA): 5.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 6.3" "Colon - Enteric glia cells, Kidney - Proximal tubular cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "HPA029460, HPA064488, HPA074437" Supported Approved "Nucleoplasm,Golgi apparatus,Vesicles,Plasma membrane,Focal adhesion sites" "Intracellular and membrane" "Cell adhesion" NA NA 16000 "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" "Vesicles, Plasma membrane" "Nucleoplasm, Golgi apparatus, Focal adhesion sites" "HPA029460: , HPA064488: , HPA074437: " "unprognostic (6.80e-3)" "potential prognostic favorable (1.23e-5)" "unprognostic (1.06e-1)" "unprognostic (7.30e-2)" PCDH17 "PCDH68, PCH68" ENSG00000118946 "Protocadherin 17" O14917 13 57631744-57729311 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 14.7;lung: 13.0;lymphoid tissue: 23.6" "Cell type enhanced" "Detected in many" "Astrocytes: 139.5;Bergmann glia: 129.5;Brain excitatory neurons: 88.5;Brain inhibitory neurons: 114.8;Late primary spermatocytes: 112.9;Lymphatic endothelial cells: 167.9;Oligodendrocyte progenitor cells: 255.8;Oligodendrocytes: 141.7;Other brain neurons: 139.4;Pancreatic duct cells: 130.7;Pancreatic islet cells: 263.9;Schwann cells: 82.4;Vascular endothelial cells: 218.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 15.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 11.2;Neuroblastoma: 6.4" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Liver - Vascular endothelial cells, Lung - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026817 Uncertain Approved "Vesicles,Plasma membrane,Cytosol" NA NA 1000000 "Cluster 73: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 2 "Vesicles, Cytosol" "Plasma membrane" "HPA026817: " "unprognostic (1.77e-2)" "unprognostic (3.23e-2)" "unprognostic (9.95e-2)" "unprognostic (3.43e-2)" "unprognostic (2.93e-1)" "unprognostic (1.05e-1)" "unprognostic (9.91e-2)" "unprognostic (2.20e-2)" "unprognostic (1.05e-2)" "unprognostic (1.48e-1)" "validated prognostic favorable (4.40e-7)" "validated prognostic favorable (7.60e-4)" "unprognostic (2.53e-3)" "unprognostic (1.76e-1)" "unprognostic (1.08e-1)" "unprognostic (4.99e-2)" "unprognostic (2.90e-2)" "unprognostic (3.45e-1)" "unprognostic (5.78e-1)" "unprognostic (7.18e-2)" "unprognostic (1.95e-1)" "unprognostic (1.83e-1)" "unprognostic (8.83e-3)" "unprognostic (8.25e-2)" "unprognostic (1.84e-2)" "unprognostic (9.64e-2)" "unprognostic (8.53e-2)" "unprognostic (1.01e-1)" PCDH18 "KIAA1562, PCDH68L" ENSG00000189184 "Protocadherin 18" Q9HCL0 4 137518918-137532494 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 59.4;Decidual stromal cells: 28.0;Endometrial stromal cells: 65.1;Fibro-adipogenic progenitors: 31.4;Fibroblasts: 72.3;Hepatic stellate cells: 19.4;Leydig cells: 40.0;Pericytes: 48.3;Peritubular myoid cells: 62.6;Retinal pigment epithelial cells: 106.6;Vascular smooth muscle cells: 24.9" "Cell type enhanced" "Detected in many" "fibroblast: 46.6;pericyte: 123.4;vascular associated smooth muscle cell: 50.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 22.0;testis cancer: 35.3" "Adrenal gland - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Pituitary gland - Fibroblasts, Prostate - Fibroblasts, Spleen - Fibroblasts_1, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA017976 Approved Approved "Golgi apparatus,Cytosol" No NA 8700000 "Cluster 75: Ovary - Mixed function" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 1 Cytosol "Golgi apparatus" "HPA017976: " "unprognostic (6.38e-2)" "unprognostic (3.65e-1)" "unprognostic (2.61e-1)" "unprognostic (1.15e-1)" "unprognostic (6.32e-2)" "unprognostic (3.96e-2)" "unprognostic (2.68e-1)" "unprognostic (2.20e-1)" "unprognostic (1.48e-2)" "unprognostic (1.37e-1)" "unprognostic (2.61e-2)" "unprognostic (1.89e-3)" "unprognostic (4.05e-2)" "unprognostic (2.45e-2)" "unprognostic (1.60e-2)" "unprognostic (3.04e-1)" "unprognostic (1.50e-1)" "unprognostic (8.58e-2)" "unprognostic (5.91e-2)" "unprognostic (3.00e-1)" "unprognostic (2.66e-1)" "unprognostic (1.05e-1)" "unprognostic (4.81e-2)" "unprognostic (4.26e-3)" "potential prognostic unfavorable (6.75e-4)" "unprognostic (4.74e-2)" "unprognostic (3.09e-1)" "unprognostic (1.61e-1)" PCDH19 "EFMR, EIEE9, KIAA1313" ENSG00000165194 "Protocadherin 19" Q8TAB3 X 100291644-100410273 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.4" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 53.4;Brain inhibitory neurons: 52.9;Oligodendrocyte progenitor cells: 71.8;Other brain neurons: 53.1;Respiratory ionocytes: 20.3;Retinal amacrine cells: 66.0;Vascular endothelial cells: 23.0" "Cell type enhanced" "Detected in all" "mammillary body: 296.4" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 5.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 4.8" "Skeletal muscle - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027533 Approved Approved Cytosol NA NA 58000 "Cluster 73: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 109: Neurons - Neuronal signaling" 6 Cytosol "HPA027533: " "unprognostic (1.00e-1)" "unprognostic (6.03e-2)" "unprognostic (2.25e-1)" "unprognostic (3.21e-1)" "unprognostic (7.72e-3)" "unprognostic (3.16e-1)" "unprognostic (4.12e-2)" "unprognostic (1.76e-1)" "potential prognostic favorable (6.56e-4)" "unprognostic (1.30e-3)" "unprognostic (6.43e-2)" "unprognostic (2.64e-1)" "unprognostic (3.86e-2)" "unprognostic (9.33e-3)" "unprognostic (7.64e-2)" PCDH20 "FLJ22218, PCDH13" ENSG00000280165 "Protocadherin 20" Q8N6Y1 13 61409685-61415849 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 7.8;smooth muscle: 7.8" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 14.2;Brain inhibitory neurons: 9.1;Oligodendrocyte progenitor cells: 45.5;Oligodendrocytes: 3.1;Other brain neurons: 9.0;Paneth cells: 3.9" "Cell type enhanced" "Detected in many" "hippocampal CA4: 66.8;hippocampal dentate gyrus: 75.1;oligodendrocyte precursor cell: 47.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 3.8;Kidney cancer: 4.6" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal medulla cells, Lung - Alveolar cells type 2, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA062669 Approved "Vesicles,Cytokinetic bridge" Yes NA 6500 "Cluster 73: Brain - Neuronal signaling" "Cluster 29: Forebrain - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 35: Neurons - Synaptic function & neurogenesis" 4 Vesicles "Cytokinetic bridge" "HPA062669: " "unprognostic (3.93e-1)" "unprognostic (1.08e-1)" "unprognostic (1.62e-1)" "unprognostic (4.13e-1)" "unprognostic (1.96e-1)" "unprognostic (8.04e-2)" "unprognostic (7.11e-3)" "unprognostic (7.82e-2)" "unprognostic (3.90e-1)" "unprognostic (5.69e-2)" "unprognostic (1.05e-1)" "unprognostic (1.57e-2)" "unprognostic (1.89e-2)" PCDH7 "BH-Pcdh, PPP1R120" ENSG00000169851 "Protocadherin 7" O60245 4 30720369-31146805 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 48.2" "Cell type enhanced" "Detected in many" "Astrocytes: 554.1;Basal keratinocytes: 1177.1;Basal prostatic cells: 863.1;Brain excitatory neurons: 781.9;Brain inhibitory neurons: 732.5;Cardiomyocytes: 920.8;Choroid plexus epithelial cells: 777.1;Oligodendrocyte progenitor cells: 1332.9;Other brain neurons: 617.5;Prostatic hillock cells: 738.5;Renal collecting duct principal cells: 571.0;Retinal amacrine cells: 809.0;Smooth muscle cells: 759.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Breast - Breast myoepithelial cells, Heart muscle - Cardiomyocytes, Skeletal muscle - Fibroblasts, Skin - Mitotic cells (Skin), Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011866, HPA046521" Uncertain Enhanced "Plasma membrane,Cell Junctions" NA NA 190000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 109: Neurons - Neuronal signaling" 10 "Plasma membrane, Cell Junctions" "HPA011866: , HPA046521: " "unprognostic (1.43e-3)" "unprognostic (3.08e-1)" "unprognostic (1.43e-1)" "unprognostic (6.36e-2)" "unprognostic (3.98e-2)" "unprognostic (1.42e-1)" "unprognostic (9.88e-2)" "potential prognostic favorable (2.32e-5)" "unprognostic (1.96e-1)" "unprognostic (7.15e-2)" "unprognostic (2.17e-2)" "potential prognostic unfavorable (1.29e-4)" "unprognostic (1.57e-2)" "unprognostic (2.89e-2)" "unprognostic (1.49e-2)" "unprognostic (9.49e-3)" "unprognostic (1.07e-1)" "unprognostic (1.41e-2)" "unprognostic (1.47e-1)" "unprognostic (7.96e-2)" "unprognostic (1.09e-1)" "unprognostic (1.54e-3)" "unprognostic (8.12e-2)" "potential prognostic unfavorable (1.57e-4)" "unprognostic (1.15e-1)" "unprognostic (1.64e-1)" "unprognostic (3.83e-2)" PCDH8 "ARCADLIN, PAPC" ENSG00000136099 "Protocadherin 8" O95206 13 52842889-52848641 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "brain: 12.3" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 6.3;Brain excitatory neurons: 15.8;Brain inhibitory neurons: 28.7;Late primary spermatocytes: 5.5;Müller glia: 25.6;Other brain neurons: 24.6;Prostatic club cells: 7.9;Retinal amacrine cells: 5.8;Retinal bipolar cells: 13.3" "Cell type enhanced" "Detected in many" "CGE interneuron: 75.5" "Cancer enhanced" "Detected in single" "Glioblastoma Multiforme (TCGA): 3.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 4.6;Neuroblastoma: 2.4" "Colon - Colon enteroendocrine cells, Prostate - Urothelial cells, Skin - Outer root sheath cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA010509 Uncertain NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 35: Neurons - Synaptic function & neurogenesis" "HPA010509: " "unprognostic (1.12e-1)" "unprognostic (1.39e-2)" PCDH9 ENSG00000184226 "Protocadherin 9" Q9HC56 13 66302834-67230445 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 38.4" "Cell type enhanced" "Detected in many" "Astrocytes: 6654.5;Bergmann glia: 9746.2;Brain excitatory neurons: 3137.6;Brain inhibitory neurons: 2065.1;Corticotrophs: 1868.5;Oligodendrocyte progenitor cells: 7818.0;Oligodendrocytes: 13244.2;Retinal ganglion cells: 3001.4" "Cell type enhanced" "Detected in all" "oligodendrocyte: 17073.9" "Cancer enriched" "Detected in some" 10 "Glioblastoma Multiforme (TCGA): 13.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "basophil: 4.5;memory B-cell: 5.3;naive B-cell: 17.3" "Group enriched" "Detected in many" 9 "B-cells: 17.3;granulocytes: 4.5" "Cancer enhanced" "Detected in many" "Rhabdoid: 32.6" "Adrenal gland - Fibroblasts, Colon - Enteric glia cells, Lung - Alveolar cells type 2, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015581 Approved Nucleoplasm,Centrosome NA NA 2000000 "Cluster 34: B-cells - Unknown function" "Cluster 73: Brain - Neuronal signaling" "Cluster 11: White matter - Signal transduction" "Cluster 3: Rhabdoid - Membrane components" "Cluster 28: Astrocytes - Homeostasis & neuron support" 3 "Nucleoplasm, Centrosome" "HPA015581: " "unprognostic (1.25e-1)" "unprognostic (4.48e-2)" "unprognostic (2.88e-3)" "unprognostic (2.46e-2)" "unprognostic (2.58e-1)" PCDHA1 ENSG00000204970 "Protocadherin alpha 1" Q9Y5I3 5 140786136-141012347 "Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.9" "Cell type enhanced" "Detected in some" "Bergmann glia: 2.2;Corticotrophs: 1.8;Early primary spermatocytes: 2.2;Early spermatids: 5.1;Lactotrophs: 3.4;Late primary spermatocytes: 2.0;Late spermatids: 1.4;Oligodendrocyte progenitor cells: 2.6;Pancreatic islet cells: 2.6;Somatotrophs: 1.7;Thyrotrophs: 2.0" "Cell type enhanced" "Detected in some" "Bergmann glia: 2.3;oligodendrocyte precursor cell: 2.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "thyroid cancer: 4.0" "Low region specificity" "Detected in many" HPA035969 Enhanced Approved "Endoplasmic reticulum,Golgi apparatus,Plasma membrane" "Secreted - unknown location" "Cell adhesion" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" "Plasma membrane" "Endoplasmic reticulum, Golgi apparatus" "HPA035969: " "unprognostic (2.74e-1)" "unprognostic (2.69e-1)" "unprognostic (4.38e-2)" PCDHA10 "CNR8, CNRN8, CNRS8, CRNR8, PCDH-ALPHA10" ENSG00000250120 "Protocadherin alpha 10" Q9Y5I2 5 140855883-141012347 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 7.7" "Group enriched" "Detected in some" 4 "Early spermatids: 6.2;Late primary spermatocytes: 2.9;Late spermatids: 2.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "thyroid cancer: 8.4" "Adrenal gland - Fibroblasts, Colon - Enteric glia cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Secreted - unknown location" "Cell adhesion" NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 2: Neurons - Nucleosome" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" "unprognostic (2.03e-2)" "unprognostic (1.36e-2)" "unprognostic (2.75e-1)" "unprognostic (3.65e-1)" "unprognostic (3.67e-2)" "potential prognostic favorable (1.08e-4)" "unprognostic (5.80e-3)" "unprognostic (3.04e-1)" "unprognostic (6.33e-2)" "unprognostic (4.29e-1)" "unprognostic (6.58e-2)" "unprognostic (6.83e-3)" "unprognostic (8.21e-2)" "unprognostic (9.12e-2)" "unprognostic (3.59e-3)" "unprognostic (5.11e-1)" PCDHA11 "CNR7, CNRN7, CNRS7, CRNR7, PCDH-ALPHA11" ENSG00000249158 "Protocadherin alpha 11" Q9Y5I1 5 140868183-141012347 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.4;parathyroid gland: 2.5;retina: 2.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" "Low region specificity" "Detected in many" HPA077160 Approved "Vesicles,Cell Junctions,Cytoplasmic bodies" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 2: Neurons - Nucleosome" "Cluster 15: Kidney cancer - Membrane components" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" "Vesicles, Cell Junctions" "Cytoplasmic bodies" "HPA077160: " "unprognostic (1.38e-2)" "unprognostic (2.45e-2)" "unprognostic (1.37e-2)" "unprognostic (1.00e-2)" "unprognostic (8.99e-2)" "unprognostic (8.21e-2)" "unprognostic (6.81e-2)" "unprognostic (6.38e-2)" "unprognostic (3.28e-2)" "unprognostic (1.47e-1)" "unprognostic (3.49e-2)" "unprognostic (7.23e-2)" "unprognostic (5.78e-3)" "unprognostic (1.18e-1)" PCDHA12 PCDH-ALPHA12 ENSG00000251664 "Protocadherin alpha 12" Q9UN75 5 140875302-141012347 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.6;lung: 1.4" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 1.0;Cholangiocytes: 2.0;Late spermatids: 1.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Adrenal gland - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" HPA035812 Approved Approved "Plasma membrane,Cytosol" No No "Cluster 27: Cerebellum - Synaptic function" "Cluster 2: Neurons - Nucleosome" "Cluster 15: Kidney cancer - Membrane components" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" "Plasma membrane, Cytosol" "HPA035812: " "unprognostic (6.84e-2)" "unprognostic (2.25e-1)" "unprognostic (7.64e-3)" "unprognostic (3.35e-2)" "unprognostic (2.71e-1)" "unprognostic (6.29e-2)" "unprognostic (2.08e-1)" "unprognostic (1.02e-1)" "unprognostic (2.29e-2)" "unprognostic (1.54e-1)" "unprognostic (1.39e-2)" PCDHA13 "CNR5, CNRN5, CNRS5, CRNR5, PCDH-ALPHA13" ENSG00000239389 "Protocadherin alpha 13" Q9Y5I0 5 140882124-141012347 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.4;parathyroid gland: 3.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 3.9" "Kidney - Macrophages, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 69: Parathyroid gland - Mixed function" "Cluster 2: Neurons - Nucleosome" "Cluster 15: Kidney cancer - Membrane components" "unprognostic (3.59e-3)" "unprognostic (1.98e-2)" "unprognostic (1.69e-1)" "unprognostic (4.13e-1)" PCDHA2 ENSG00000204969 "Protocadherin alpha 2" Q9Y5H9 5 140794852-141012347 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.1;pituitary gland: 1.4" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Bergmann glia: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 3.2" "Colon - Enteric glia cells, Testis - Early spermatids" "Low region specificity" "Detected in all" HPA035653 Uncertain Approved "Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium" Yes NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 2: Neurons - Nucleosome" "Cluster 17: Neuroblastoma - Neuronal signaling" 2 Microtubules "Cytokinetic bridge, Mitotic spindle, Primary cilium" "HPA035653: " "unprognostic (9.70e-2)" "unprognostic (1.51e-1)" "unprognostic (2.59e-2)" PCDHA3 PCDH-ALPHA3 ENSG00000255408 "Protocadherin alpha 3" Q9Y5H8 5 140801028-141012347 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Bergmann glia: 1.8;Oligodendrocyte progenitor cells: 3.5" "Cell type enhanced" "Detected in some" "Bergmann glia: 4.3;oligodendrocyte precursor cell: 3.7" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 3.1;Neuroblastoma: 3.3" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035667 Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 65: Brain - Transcription" "Cluster 2: Neurons - Nucleosome" "Cluster 15: Kidney cancer - Membrane components" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" "Nucleoplasm, Golgi apparatus" "HPA035667: " "unprognostic (2.62e-1)" "unprognostic (1.70e-1)" "unprognostic (1.50e-2)" "unprognostic (1.22e-1)" "unprognostic (3.87e-2)" PCDHA4 "CNR1, CNRN1, CRNR1, PCDH-ALPHA4" ENSG00000204967 "Protocadherin alpha 4" Q9UN74 5 140806929-141012347 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.9" "Cell type enhanced" "Detected in some" "Astrocytes: 1.3;Bergmann glia: 5.6;Brain excitatory neurons: 2.1;Brain inhibitory neurons: 2.3;Ependymal cells: 1.8;Oligodendrocyte progenitor cells: 7.4;Oligodendrocytes: 1.4;Other brain neurons: 1.1;Respiratory deuterosomal cells: 1.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 5.9" "Testis - Early spermatids" "Low region specificity" "Detected in all" "HPA043180, HPA073478" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 1 "Nucleoplasm, Plasma membrane" Cytosol "HPA043180: , HPA073478: " "unprognostic (3.07e-3)" "unprognostic (3.12e-1)" "unprognostic (6.56e-2)" "unprognostic (3.76e-1)" "unprognostic (1.52e-1)" "unprognostic (8.83e-2)" "unprognostic (2.43e-2)" "unprognostic (4.58e-3)" "unprognostic (3.18e-2)" "unprognostic (5.89e-2)" "unprognostic (7.87e-2)" "unprognostic (2.15e-1)" "unprognostic (7.16e-3)" "unprognostic (3.28e-3)" "unprognostic (2.42e-1)" "potential prognostic unfavorable (3.33e-5)" "unprognostic (7.80e-3)" "unprognostic (2.21e-1)" PCDHA5 "CNR6, CNRN6, CNRS6, CRNR6, PCDH-ALPHA5" ENSG00000204965 "Protocadherin alpha 5" Q9Y5H7 5 140821604-141012347 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 5 "brain: 2.2" "Cell type enhanced" "Detected in some" "Bergmann glia: 3.7;Brain excitatory neurons: 2.8;Brain inhibitory neurons: 2.0;Oligodendrocyte progenitor cells: 5.3;Oligodendrocytes: 1.2;Other brain neurons: 1.3" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Neuroblastoma: 1.6" "Testis - Early spermatids" "Low region specificity" "Detected in many" HPA044557 Approved Approved "Nuclear speckles,Plasma membrane,Mitochondria" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 2: Neurons - Nucleosome" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" "Plasma membrane" "Nuclear speckles, Mitochondria" "HPA044557: " "unprognostic (9.17e-2)" "unprognostic (1.18e-1)" "unprognostic (6.41e-2)" PCDHA6 "CNR2, CNRS2, CRNR2, PCDH-ALPHA6" ENSG00000081842 "Protocadherin alpha 6" Q9UN73 5 140827958-141012347 "Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.4" "Cell type enhanced" "Detected in some" "Astrocytes: 15.4;Bergmann glia: 46.4;Brain excitatory neurons: 34.3;Brain inhibitory neurons: 36.1;Ependymal cells: 16.3;Oligodendrocyte progenitor cells: 65.9;Oligodendrocytes: 14.1;Other brain neurons: 21.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA059326, HPA078110" Enhanced Approved Vesicles "Secreted in brain" "Cell adhesion" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 2: Neurons - Nucleosome" "Cluster 15: Kidney cancer - Membrane components" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" Vesicles "HPA059326: , HPA078110: " "unprognostic (9.14e-2)" "unprognostic (2.60e-2)" "unprognostic (1.51e-1)" "unprognostic (4.95e-2)" "unprognostic (9.18e-2)" "unprognostic (2.41e-1)" "unprognostic (3.27e-2)" "unprognostic (6.67e-2)" PCDHA7 "CNR4, CNRS4, CRNR4" ENSG00000204963 "Protocadherin alpha 7" Q9UN72 5 140834248-141012347 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.3" "Cell type enriched" "Detected in single" 11 "Myosatellite cells: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 2: Neurons - Nucleosome" "Cluster 4: Non-specific - Transcription" "Cluster 46: Skeletal myocytes - Muscle structure & formation" "unprognostic (1.79e-1)" "unprognostic (4.00e-1)" "unprognostic (1.53e-2)" PCDHA8 ENSG00000204962 "Protocadherin alpha 8" Q9Y5H6 5 140841187-141012347 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Neuroblastoma: 1.3" "Testis - Early spermatids" HPA044585 Uncertain Approved "Plasma membrane,Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium" Yes NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 35: Non-specific - DNA binding" "Cluster 10: Ciliated cells - Ion channel activity" "Plasma membrane, Microtubules" "Cytokinetic bridge, Mitotic spindle, Primary cilium" "HPA044585: " "unprognostic (5.71e-2)" "unprognostic (1.12e-1)" PCDHA9 "KIAA0345, PCDH-ALPHA9" ENSG00000204961 "Protocadherin alpha 9" Q9Y5H5 5 140847772-141012347 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.0;testis: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" NA NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 110: Mural cells - ECM organization" 10 "unprognostic (1.18e-1)" "unprognostic (7.04e-2)" "unprognostic (2.78e-2)" PCDHAC1 ENSG00000248383 "Protocadherin alpha subfamily C, 1" Q9H158 5 140926299-141012347 "Predicted membrane proteins" "Cell adhesion" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 24 "parathyroid gland: 28.0" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Lung Adenocarcinoma (TCGA): 1.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 3.2;Rhabdoid: 3.4" "Colon - Colon enteroendocrine cells, Lung - Alveolar cells type 2, Testis - Spermatocytes" "Low region specificity" "Detected in all" HPA052775 Approved Nucleoplasm,Nucleoli,Vesicles No No "Cluster 69: Parathyroid gland - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Nucleoplasm, Nucleoli" Vesicles "HPA052775: " "unprognostic (1.49e-1)" "unprognostic (5.23e-3)" "unprognostic (1.15e-1)" "unprognostic (1.05e-3)" "unprognostic (1.45e-1)" "unprognostic (1.48e-1)" PCDHAC2 PCDH-ALPHA-C2 ENSG00000243232 "Protocadherin alpha subfamily C, 2" Q9Y5I4 5 140966470-141012347 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "parathyroid gland: 40.4" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 1.4;Myosatellite cells: 1.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 5.9" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076190 Approved Nucleoplasm,Mitochondria NA NA 9700000 "Cluster 69: Parathyroid gland - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 81: Alveolar cells - Lung function" Nucleoplasm Mitochondria "HPA076190: " "unprognostic (1.92e-1)" "unprognostic (3.24e-1)" "unprognostic (2.56e-2)" "unprognostic (9.02e-2)" "unprognostic (1.60e-1)" "unprognostic (8.04e-2)" "unprognostic (1.61e-1)" "unprognostic (5.44e-2)" "potential prognostic unfavorable (1.46e-4)" "unprognostic (1.13e-1)" PCDHB1 PCDH-BETA1 ENSG00000171815 "Protocadherin beta 1" Q9Y5F3 5 141051374-141059346 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "skeletal muscle: 1.3" "Cell type enhanced" "Detected in some" "Corticotrophs: 17.3;Ependymal cells: 5.3;Epididymal efferent duct ciliated cells: 3.8;Fallopian tube ciliated cells: 2.1;Lactotrophs: 2.3;Pituicytes/FSCs: 3.1;Pituitary stem cells: 2.8;Respiratory ciliated cells: 3.7;Somatotrophs: 1.8;Thyrotrophs: 3.4" "Group enriched" "Detected in some" 4 "ependymal cell: 5.2;oligodendrocyte precursor cell: 1.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Enteric glia cells, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA053921 Uncertain Uncertain "Nucleoplasm,Plasma membrane" NA NA "Cluster 40: Non-specific - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" Nucleoplasm "Plasma membrane" "HPA053921: " "potential prognostic unfavorable (1.19e-4)" "unprognostic (1.59e-2)" PCDHB10 ENSG00000120324 "Protocadherin beta 10" Q9UN67 5 141192353-141195647 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Brain inhibitory neurons: 5.2;Corticotrophs: 13.4;Decidual stromal cells: 4.5;Hepatic stellate cells: 6.5;Lactotrophs: 6.6;Retinal bipolar cells: 5.6;Retinal pigment epithelial cells: 4.3" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 11.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 10.6" "Kidney - Fibroblasts" HPA013445 Uncertain NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 2 "HPA013445: " "unprognostic (9.82e-2)" "unprognostic (5.71e-2)" "unprognostic (3.42e-1)" "unprognostic (4.11e-2)" "unprognostic (3.65e-1)" "unprognostic (3.54e-3)" "unprognostic (2.92e-1)" "unprognostic (1.39e-1)" "unprognostic (1.55e-1)" "potential prognostic favorable (7.59e-5)" "unprognostic (1.01e-1)" "unprognostic (3.18e-1)" "unprognostic (1.35e-1)" "unprognostic (1.95e-2)" "unprognostic (7.17e-2)" "unprognostic (9.47e-3)" "unprognostic (4.74e-2)" "unprognostic (1.39e-1)" "unprognostic (1.86e-1)" "unprognostic (2.78e-2)" "unprognostic (2.91e-1)" "unprognostic (2.12e-2)" "unprognostic (1.09e-1)" "unprognostic (1.91e-2)" "unprognostic (5.05e-2)" "unprognostic (4.36e-2)" PCDHB11 "ME2, PCDH-BETA11" ENSG00000197479 "Protocadherin beta 11" Q9Y5F2 5 141199610-141203779 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Corticotrophs: 5.6;Endometrial secretory cells: 3.9;Fibroblasts: 4.0;Pancreatic acinar cells: 3.9;Retinal pigment epithelial cells: 12.8;Thymic myoid cells: 8.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Prostate - Fibroblasts" HPA045042 Uncertain Approved "Plasma membrane" NA NA "Cluster 70: Non-specific - Protein processing" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 108: Fibroblasts - ECM organization" "Plasma membrane" "HPA045042: " "unprognostic (1.39e-1)" "unprognostic (1.11e-1)" "unprognostic (1.77e-1)" "unprognostic (1.01e-1)" "unprognostic (2.68e-1)" "unprognostic (6.27e-2)" "unprognostic (8.99e-2)" "unprognostic (2.21e-2)" "unprognostic (8.25e-2)" "unprognostic (1.20e-1)" "unprognostic (2.46e-1)" "unprognostic (4.67e-2)" "unprognostic (6.91e-2)" "unprognostic (3.35e-1)" "unprognostic (1.05e-1)" "unprognostic (2.95e-2)" "unprognostic (8.68e-2)" "unprognostic (6.88e-3)" "unprognostic (1.10e-1)" "unprognostic (2.09e-2)" "unprognostic (1.17e-1)" "unprognostic (2.38e-1)" PCDHB12 PCDH-BETA12 ENSG00000120328 "Protocadherin beta 12" Q9Y5F1 5 141208697-141212571 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Brain inhibitory neurons: 4.0;Corticotrophs: 13.4;Ependymal cells: 4.0;Gastric progenitor cells: 5.1;Hepatic stellate cells: 6.5;Lactotrophs: 7.6;Myosatellite cells: 4.0;Pituitary stem cells: 4.9;Retinal pigment epithelial cells: 4.3;Thymic myoid cells: 6.8;Thyrotrophs: 4.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 3.3" "Breast - Fibroblasts, Prostate - Fibroblasts, Testis - Early spermatids" HPA045042 Uncertain Approved "Plasma membrane" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 8 "Plasma membrane" "HPA045042: " "unprognostic (1.84e-1)" "unprognostic (1.37e-1)" "unprognostic (2.43e-1)" "unprognostic (4.25e-2)" "unprognostic (1.06e-1)" "unprognostic (8.32e-3)" "unprognostic (8.64e-3)" "unprognostic (3.04e-1)" "unprognostic (1.02e-1)" "unprognostic (2.07e-1)" "unprognostic (9.27e-3)" "unprognostic (1.24e-1)" "unprognostic (4.65e-2)" "unprognostic (1.59e-2)" "unprognostic (1.60e-1)" "unprognostic (1.56e-1)" PCDHB13 PCDH-BETA13 ENSG00000187372 "Protocadherin beta 13" Q9Y5F0 5 141213919-141218979 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Corticotrophs: 8.4;Hepatic stellate cells: 6.5;Lactotrophs: 5.4;Pituitary stem cells: 5.6;Retinal pigment epithelial cells: 8.5;Salivary ionocytes: 4.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 2.9" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.9" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 70: Non-specific - Protein processing" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 2 "unprognostic (1.59e-1)" "unprognostic (1.21e-2)" "unprognostic (3.75e-1)" "unprognostic (1.47e-1)" "unprognostic (2.65e-3)" "unprognostic (2.77e-1)" "unprognostic (1.74e-1)" "unprognostic (1.51e-1)" "unprognostic (3.61e-3)" "potential prognostic favorable (1.34e-4)" "unprognostic (9.08e-2)" "unprognostic (7.72e-3)" "unprognostic (5.90e-2)" "unprognostic (2.40e-2)" "unprognostic (2.00e-1)" "unprognostic (7.50e-3)" "unprognostic (2.92e-1)" "unprognostic (2.02e-1)" "unprognostic (3.28e-1)" "unprognostic (1.04e-1)" "unprognostic (3.74e-1)" "unprognostic (3.66e-2)" "unprognostic (1.23e-2)" "unprognostic (6.17e-3)" "unprognostic (1.03e-1)" PCDHB14 PCDH-BETA14 ENSG00000120327 "Protocadherin beta 14" Q9Y5E9 5 141223343-141227759 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 6 "Astrocytes: 12.3;Bergmann glia: 11.9;Brain excitatory neurons: 11.5;Brain inhibitory neurons: 13.9;Ependymal cells: 10.1;Oligodendrocyte progenitor cells: 9.8;Oligodendrocytes: 4.9;Other brain neurons: 6.0;Podocytes: 4.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 10.8" "Adipose subcutaneous - Adipose progenitor cells, Prostate - Fibroblasts, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "HPA007692, HPA045248" Uncertain Approved Vesicles NA NA 31000 "Cluster 74: Non-specific - Signal transduction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 28: Astrocytes - Homeostasis & neuron support" 15 Vesicles "HPA007692: , HPA045248: " "unprognostic (3.46e-1)" "unprognostic (3.99e-2)" "unprognostic (1.77e-1)" "unprognostic (5.04e-2)" "unprognostic (4.63e-2)" "unprognostic (2.33e-2)" "unprognostic (1.37e-2)" "unprognostic (1.77e-1)" "unprognostic (1.52e-2)" "unprognostic (3.10e-1)" "unprognostic (8.37e-3)" "unprognostic (7.33e-2)" "unprognostic (2.80e-1)" "unprognostic (1.20e-2)" "unprognostic (2.27e-2)" "unprognostic (2.46e-3)" "unprognostic (1.22e-1)" "unprognostic (1.01e-1)" "unprognostic (2.23e-2)" "unprognostic (4.23e-2)" "unprognostic (2.00e-1)" "unprognostic (6.60e-2)" "unprognostic (1.27e-1)" "unprognostic (1.93e-2)" "unprognostic (2.86e-2)" "unprognostic (8.38e-2)" "unprognostic (4.05e-2)" "unprognostic (2.17e-1)" "unprognostic (7.06e-2)" "unprognostic (5.27e-2)" "unprognostic (3.00e-2)" PCDHB15 PCDH-BETA15 ENSG00000113248 "Protocadherin beta 15" Q9Y5E8 5 141245395-141249365 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Corticotrophs: 6.1;Decidual stromal cells: 9.3;Early spermatids: 6.6;Late primary spermatocytes: 12.4;Oligodendrocyte progenitor cells: 10.9;Salivary duct cells: 4.9;Salivary ionocytes: 5.4;Thymic myoid cells: 8.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 4.5" "Skeletal muscle - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "HPA007172, CAB026471" Uncertain Uncertain "Nucleoplasm,Centrosome,Basal body" NA NA 3600000 "Cluster 75: Ovary - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 108: Fibroblasts - ECM organization" "Centrosome, Basal body" Nucleoplasm "CAB026471: , HPA007172: " "unprognostic (1.21e-1)" "unprognostic (2.61e-1)" "unprognostic (2.69e-1)" "unprognostic (6.70e-3)" "unprognostic (3.93e-2)" "validated prognostic favorable (2.45e-5)" "validated prognostic favorable (4.22e-4)" "unprognostic (2.64e-2)" "unprognostic (2.95e-2)" "unprognostic (2.89e-2)" "unprognostic (1.83e-1)" "unprognostic (2.38e-2)" "unprognostic (1.31e-1)" "unprognostic (2.28e-1)" "unprognostic (8.03e-2)" "unprognostic (3.48e-2)" "unprognostic (1.13e-1)" "unprognostic (1.98e-1)" "unprognostic (9.58e-2)" "unprognostic (2.82e-2)" "unprognostic (4.74e-1)" "unprognostic (6.48e-2)" PCDHB16 "KIAA1621, ME1, PCDH-BETA16, PCDH3X, PCDHB8a" ENSG00000272674 "Protocadherin beta 16" Q9NRJ7 5 141182387-141186226 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in single" "Podocytes: 1.3" "Cell type enhanced" "Detected in single" "Bergmann glia: 2.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" HPA014668 Approved "Vesicles,Plasma membrane" NA NA 27000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 105: Non-specific - Mixed function" 1 "Vesicles, Plasma membrane" "HPA014668: " "unprognostic (1.97e-1)" "unprognostic (2.78e-2)" "unprognostic (7.51e-2)" "unprognostic (2.99e-2)" "unprognostic (7.77e-2)" "unprognostic (4.90e-2)" "unprognostic (1.13e-1)" "unprognostic (1.70e-2)" "unprognostic (6.90e-3)" "unprognostic (2.68e-1)" "unprognostic (1.10e-2)" "unprognostic (4.46e-3)" "unprognostic (1.74e-1)" "unprognostic (4.11e-1)" "unprognostic (2.86e-2)" "unprognostic (8.11e-2)" "unprognostic (3.95e-2)" "unprognostic (6.92e-3)" "unprognostic (1.24e-1)" "unprognostic (6.51e-2)" "unprognostic (2.28e-2)" "unprognostic (7.66e-3)" "unprognostic (6.59e-2)" "unprognostic (3.80e-3)" "unprognostic (1.52e-1)" PCDHB2 PCDH-BETA2 ENSG00000112852 "Protocadherin beta 2" Q9Y5E7 5 141094606-141098703 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 5.3;Early primary spermatocytes: 5.3;Endometrial stromal cells: 5.6;Gastric progenitor cells: 7.7;Late primary spermatocytes: 30.5" "Cell type enhanced" "Detected in many" "hippocampal dentate gyrus: 9.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Testis - Early spermatids" "Low region specificity" "Detected in many" HPA007548 Enhanced Approved Nucleoplasm NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 34: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 1 Nucleoplasm "HPA007548: " "unprognostic (1.44e-3)" "unprognostic (1.48e-3)" "unprognostic (1.30e-1)" "unprognostic (1.91e-3)" "unprognostic (1.05e-2)" "unprognostic (8.23e-2)" "unprognostic (1.93e-3)" "unprognostic (1.93e-1)" "unprognostic (7.45e-2)" "unprognostic (1.27e-2)" "unprognostic (2.09e-1)" "unprognostic (3.88e-2)" "unprognostic (1.61e-1)" "unprognostic (1.07e-2)" "unprognostic (1.33e-1)" "unprognostic (2.42e-2)" "unprognostic (8.85e-2)" "unprognostic (4.93e-2)" "unprognostic (3.03e-1)" "unprognostic (8.84e-2)" "unprognostic (2.61e-1)" "unprognostic (1.20e-1)" "unprognostic (6.63e-2)" "unprognostic (1.05e-1)" "potential prognostic unfavorable (2.36e-4)" "unprognostic (1.15e-1)" "unprognostic (1.32e-1)" "unprognostic (1.89e-1)" PCDHB3 PCDH-BETA3 ENSG00000113205 "Protocadherin beta 3" Q9Y5E6 5 141100473-141103827 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Brain inhibitory neurons: 2.6;Breast myoepithelial cells: 4.3;Corticotrophs: 7.1;Lactotrophs: 4.4;Pancreatic islet cells: 2.6;Pituitary stem cells: 2.8;Respiratory ionocytes: 2.5;Retinal pigment epithelial cells: 4.3;Schwann cells: 2.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" "Low region specificity" "Detected in all" HPA050296 Uncertain Supported Vesicles NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 83 Vesicles "HPA050296: " "unprognostic (3.95e-2)" "unprognostic (1.15e-1)" "unprognostic (1.02e-1)" "unprognostic (5.97e-3)" "unprognostic (2.32e-1)" "unprognostic (1.51e-1)" "unprognostic (7.38e-3)" "unprognostic (2.94e-1)" "unprognostic (1.38e-1)" "unprognostic (3.37e-3)" "unprognostic (1.56e-1)" "unprognostic (9.26e-2)" "unprognostic (1.27e-1)" "unprognostic (1.33e-1)" "unprognostic (3.01e-3)" "unprognostic (5.55e-2)" "unprognostic (2.39e-2)" "unprognostic (2.72e-1)" "unprognostic (1.35e-1)" "unprognostic (8.92e-3)" "unprognostic (2.04e-1)" PCDHB4 PCDH-BETA4 ENSG00000081818 "Protocadherin beta 4" Q9Y5E5 5 141121818-141125623 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast lactating cells: 16.9;Corticotrophs: 17.9;Fibroblasts: 9.9;Medullary thymic epithelial cells: 9.6;Oligodendrocyte progenitor cells: 14.1;Pancreatic acinar cells: 12.7;Pancreatic islet cells: 12.4;Respiratory ionocytes: 10.2;Schwann cells: 9.2;Smooth muscle cells: 10.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 3.3" "Adrenal gland - Fibroblasts, Kidney - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014466 Approved Approved "Nuclear membrane,Plasma membrane" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 22: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 108: Fibroblasts - ECM organization" 1 "Plasma membrane" "Nuclear membrane" "HPA014466: " "unprognostic (5.68e-2)" "unprognostic (4.29e-1)" "unprognostic (1.43e-1)" "unprognostic (1.49e-2)" "unprognostic (1.42e-2)" "unprognostic (1.10e-1)" "potential prognostic favorable (1.26e-4)" "unprognostic (1.88e-2)" "unprognostic (2.62e-1)" "unprognostic (2.54e-1)" "unprognostic (7.83e-2)" "unprognostic (7.59e-2)" "unprognostic (3.70e-1)" "unprognostic (1.88e-2)" "unprognostic (4.59e-2)" "unprognostic (1.39e-1)" "unprognostic (1.97e-1)" "unprognostic (3.19e-3)" PCDHB5 "DKFZp586B0217, PCDH-BETA5" ENSG00000113209 "Protocadherin beta 5" Q9Y5E4 5 141135206-141138615 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Late primary spermatocytes: 57.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 20.0" "Skeletal muscle - Fibroblasts, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "HPA013191, HPA067473" Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 65: Brain - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 4 "Plasma membrane" Vesicles "HPA013191: , HPA067473: " "unprognostic (2.84e-2)" "unprognostic (2.50e-1)" "unprognostic (2.60e-1)" "unprognostic (1.28e-3)" "unprognostic (1.97e-1)" "unprognostic (3.29e-1)" "unprognostic (3.21e-1)" "unprognostic (5.38e-2)" "unprognostic (1.22e-3)" "unprognostic (4.49e-3)" "unprognostic (6.29e-3)" "unprognostic (3.64e-1)" "unprognostic (7.01e-2)" "unprognostic (3.16e-1)" "unprognostic (2.61e-1)" "unprognostic (1.45e-1)" "unprognostic (8.34e-2)" "unprognostic (4.46e-1)" "unprognostic (1.98e-3)" "unprognostic (2.71e-2)" "unprognostic (9.69e-2)" "unprognostic (3.58e-2)" "potential prognostic unfavorable (2.55e-4)" "unprognostic (5.10e-2)" "unprognostic (6.18e-2)" "unprognostic (1.07e-2)" PCDHB6 PCDH-BETA6 ENSG00000113211 "Protocadherin beta 6" Q9Y5E3 5 141150057-141153287 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Group enriched" "Detected in some" 5 "Adrenal medulla cells: 10.6;Late primary spermatocytes: 25.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 4.5" "Testis - Early spermatids" "Low region specificity" "Detected in many" "HPA029566, HPA075308" Uncertain Approved Nucleoplasm NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" Nucleoplasm "HPA029566: , HPA075308: " "unprognostic (1.05e-2)" "unprognostic (3.53e-2)" "unprognostic (8.31e-2)" "unprognostic (1.59e-2)" "unprognostic (2.18e-1)" "unprognostic (1.19e-1)" "unprognostic (2.39e-1)" "unprognostic (3.92e-1)" "unprognostic (3.44e-2)" "unprognostic (1.52e-1)" "unprognostic (9.06e-3)" "unprognostic (3.33e-2)" "unprognostic (4.29e-2)" "unprognostic (9.77e-2)" PCDHB7 PCDH-BETA7 ENSG00000113212 "Protocadherin beta 7" Q9Y5E2 5 141172644-141176383 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 6 "Early spermatids: 34.5;Late primary spermatocytes: 62.2;Late spermatids: 33.2" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in many" 4 "Glioblastoma Multiforme (TCGA): 9.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 3.9" "Adrenal gland - Fibroblasts, Kidney - Fibroblasts, Prostate - Fibroblasts, Stomach - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059271 Approved NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 19 "HPA059271: " "unprognostic (2.24e-1)" "unprognostic (8.92e-2)" "unprognostic (2.85e-1)" "unprognostic (2.82e-1)" "unprognostic (3.45e-2)" "unprognostic (2.29e-2)" "unprognostic (3.32e-2)" "unprognostic (4.05e-2)" "unprognostic (1.76e-2)" "unprognostic (2.10e-1)" "unprognostic (6.79e-2)" "unprognostic (3.41e-1)" "unprognostic (6.59e-2)" "unprognostic (3.28e-2)" "unprognostic (5.93e-2)" "unprognostic (2.36e-1)" "unprognostic (7.32e-2)" PCDHB8 "PCDH-BETA8, PCDH3I" ENSG00000120322 "Protocadherin beta 8" Q9UN66 5 141177790-141180539 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" HPA057773 Uncertain NA NA "Cluster 67: Testis - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 105: Non-specific - Mixed function" 1 "HPA057773: " "unprognostic (2.28e-2)" "potential prognostic unfavorable (3.21e-4)" "unprognostic (2.62e-1)" "unprognostic (1.56e-1)" "unprognostic (5.35e-2)" "unprognostic (2.63e-1)" "unprognostic (1.55e-2)" "unprognostic (7.54e-3)" "unprognostic (5.12e-2)" "unprognostic (3.24e-2)" "unprognostic (2.45e-3)" "unprognostic (7.85e-2)" "unprognostic (4.36e-3)" "unprognostic (2.99e-1)" "unprognostic (1.58e-2)" "unprognostic (6.35e-2)" "unprognostic (2.08e-2)" "unprognostic (5.44e-2)" "unprognostic (2.71e-1)" "unprognostic (3.22e-2)" "unprognostic (7.03e-3)" PCDHB9 "PCDH-BETA9, PCDH3H" ENSG00000177839 "Protocadherin beta 9" Q9Y5E1 5 141187127-141191541 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 4.1" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 42.5;Retinal bipolar cells: 11.0;Sertoli cells: 9.5" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 8.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 4.4" "Lung - Fibroblasts_1, Pituitary gland - Lactotropes, Prostate - Fibroblasts, Stomach - Fibroblasts" HPA013445 Uncertain NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 1 "HPA013445: " "unprognostic (1.63e-1)" "unprognostic (4.62e-2)" "unprognostic (3.53e-1)" "unprognostic (1.15e-1)" "unprognostic (2.12e-1)" "unprognostic (1.25e-3)" "unprognostic (3.27e-2)" "unprognostic (1.44e-1)" "unprognostic (1.50e-1)" "unprognostic (2.68e-2)" "unprognostic (1.49e-1)" "unprognostic (1.42e-1)" "unprognostic (4.56e-3)" "unprognostic (2.07e-2)" "unprognostic (5.21e-2)" "unprognostic (1.91e-1)" "unprognostic (1.36e-1)" "unprognostic (2.50e-2)" "unprognostic (3.27e-2)" "unprognostic (7.74e-2)" "unprognostic (3.11e-2)" "unprognostic (7.60e-3)" "unprognostic (1.85e-2)" "unprognostic (1.64e-2)" "unprognostic (1.63e-1)" PCDHGA1 PCDH-GAMMA-A1 ENSG00000204956 "Protocadherin gamma subfamily A, 1" Q9Y5H4 5 141330514-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 10.6;Cardiomyocytes: 13.2;Corticotrophs: 24.2;Lactotrophs: 21.0;Myonuclei: 9.0;Pituitary stem cells: 10.3;Sertoli cells: 13.7;Somatotrophs: 14.0;Thymic myoid cells: 6.8;Thyrotrophs: 19.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA036547" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 15: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: , HPA010580: , HPA036547: " "unprognostic (1.46e-1)" "unprognostic (4.74e-1)" "unprognostic (1.93e-1)" "unprognostic (3.22e-3)" "unprognostic (4.01e-1)" "unprognostic (2.03e-3)" "unprognostic (3.97e-3)" "unprognostic (1.23e-1)" "unprognostic (5.68e-3)" PCDHGA10 PCDH-GAMMA-A10 ENSG00000253846 "Protocadherin gamma subfamily A, 10" Q9Y5H3 5 141412987-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 14.9" "Group enriched" "Detected in some" 5 "Astrocytes: 30.1;Bergmann glia: 39.3;Brain excitatory neurons: 19.2;Brain inhibitory neurons: 16.0;Choroid plexus epithelial cells: 14.1;Ependymal cells: 12.5;Oligodendrocyte progenitor cells: 25.3;Oligodendrocytes: 10.0;Other brain neurons: 13.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA077276" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA 30000 "Cluster 73: Brain - Neuronal signaling" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 98: Neurons - Neurotransmission & signaling" 5 "Nucleoplasm, Plasma membrane" "Vesicles, Cytosol" "HPA008755: , HPA010580: , HPA077276: " "unprognostic (3.44e-2)" "unprognostic (2.06e-1)" "unprognostic (1.78e-1)" "potential prognostic unfavorable (2.67e-5)" "unprognostic (2.85e-1)" "unprognostic (7.05e-2)" "unprognostic (3.73e-2)" "unprognostic (1.15e-1)" "unprognostic (3.34e-2)" "unprognostic (5.47e-2)" "unprognostic (7.08e-3)" "unprognostic (6.85e-2)" "unprognostic (1.39e-2)" "unprognostic (1.93e-1)" "unprognostic (2.11e-1)" "unprognostic (7.01e-3)" "unprognostic (2.23e-1)" "unprognostic (8.07e-2)" "unprognostic (2.62e-1)" "unprognostic (2.79e-2)" "unprognostic (2.72e-2)" "unprognostic (8.59e-2)" "unprognostic (3.92e-2)" "unprognostic (2.58e-1)" "unprognostic (8.96e-2)" "unprognostic (7.71e-3)" "unprognostic (2.90e-1)" "unprognostic (2.84e-1)" "unprognostic (2.08e-2)" PCDHGA11 PCDH-GAMMA-A11 ENSG00000253873 "Protocadherin gamma subfamily A, 11" Q9Y5H2 5 141421047-141512975 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Astrocytes: 1.4;Choroid plexus epithelial cells: 2.4" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in some" "Skin Cutaneous Melanoma (TCGA): 3.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 9.1" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" "Intracellular and membrane" "Cell adhesion" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 15: Non-specific - Transcription" "Cluster 69: Skin cancer - ECM organization" "Cluster 22: Non-specific - Basic cellular functions" 1 "Plasma membrane" "Nucleoplasm, Vesicles, Cytosol" "HPA008755: , HPA010580: " "unprognostic (1.05e-2)" "unprognostic (7.07e-2)" "unprognostic (1.91e-1)" "unprognostic (2.68e-1)" "unprognostic (5.29e-3)" "unprognostic (2.56e-3)" "unprognostic (6.06e-3)" "unprognostic (1.49e-2)" "unprognostic (7.97e-2)" "unprognostic (3.46e-2)" "unprognostic (1.64e-1)" "unprognostic (1.29e-2)" PCDHGA12 "CDH21, FIB3, KIAA0588, PCDH-GAMMA-A12" ENSG00000253159 "Protocadherin gamma subfamily A, 12" O60330 5 141430507-141512975 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 9.2" "Cell type enhanced" "Detected in some" "Astrocytes: 2.5;Bergmann glia: 1.5;Choroid plexus epithelial cells: 1.3;Oligodendrocyte progenitor cells: 2.8" "Low cell type specificity" "Detected in some" "Group enriched" "Detected in many" 5 "Glioblastoma Multiforme (TCGA): 5.6;Skin Cutaneous Melanoma (TCGA): 16.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "memory B-cell: 1.2" "Lineage enriched" "Detected in single" 4 "B-cells: 1.2" "Cancer enhanced" "Detected in some" "Sarcoma: 5.8;skin cancer: 5.7" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells, Lung - Fibroblasts_1" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA 24000 "Cluster 73: Brain - Neuronal signaling" "Cluster 44: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 28: Astrocytes - Homeostasis & neuron support" 1 "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: , HPA010580: " "unprognostic (1.48e-2)" "unprognostic (1.99e-1)" "unprognostic (5.78e-2)" "unprognostic (1.54e-1)" "unprognostic (4.91e-2)" "potential prognostic favorable (1.59e-4)" "unprognostic (1.35e-1)" "unprognostic (6.62e-3)" "unprognostic (6.62e-2)" "unprognostic (2.17e-2)" "unprognostic (1.42e-1)" "unprognostic (1.19e-3)" "unprognostic (2.98e-1)" "unprognostic (2.64e-2)" "unprognostic (3.27e-3)" "unprognostic (7.40e-2)" "unprognostic (1.96e-2)" "unprognostic (1.37e-1)" "unprognostic (1.33e-1)" PCDHGA2 PCDH-GAMMA-A2 ENSG00000081853 "Protocadherin gamma subfamily A, 2" Q9Y5H1 5 141338760-141512975 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 1.9;Bergmann glia: 1.5;Brain inhibitory neurons: 1.2;Choroid plexus epithelial cells: 1.2;Ependymal cells: 1.4;Oligodendrocyte progenitor cells: 1.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adrenal gland - Fibroblasts, Lung - Fibroblasts_1" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA038625" Approved Approved "Nucleoplasm,Nucleoli,Vesicles,Plasma membrane,Focal adhesion sites,Cytosol" NA NA "Cluster 65: Brain - Transcription" "Cluster 44: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 28: Astrocytes - Homeostasis & neuron support" "Vesicles, Plasma membrane" "Nucleoplasm, Nucleoli, Focal adhesion sites, Cytosol" "HPA008755: , HPA010580: , HPA038625: " "unprognostic (1.24e-2)" "unprognostic (4.10e-1)" "unprognostic (1.31e-1)" "unprognostic (1.52e-2)" "unprognostic (7.82e-2)" "potential prognostic favorable (2.66e-6)" "unprognostic (5.18e-3)" "unprognostic (7.04e-3)" "unprognostic (9.83e-3)" "unprognostic (3.27e-1)" "unprognostic (8.18e-2)" "unprognostic (1.21e-1)" "unprognostic (1.09e-1)" "unprognostic (8.66e-2)" "unprognostic (9.27e-3)" "unprognostic (7.41e-2)" "unprognostic (4.30e-2)" PCDHGA3 PCDH-GAMMA-A3 ENSG00000254245 "Protocadherin gamma subfamily A, 3" Q9Y5H0 5 141343829-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 3.6;Bergmann glia: 2.4;Ependymal cells: 2.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Fibroblasts_1" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 44: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 28: Astrocytes - Homeostasis & neuron support" 1 "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: , HPA010580: " "unprognostic (1.53e-1)" "unprognostic (4.16e-2)" "unprognostic (6.79e-2)" "unprognostic (3.22e-2)" "unprognostic (1.87e-2)" "unprognostic (7.63e-2)" "unprognostic (2.83e-1)" PCDHGA4 PCDH-GAMMA-A4 ENSG00000262576 "Protocadherin gamma subfamily A, 4" Q9Y5G9 5 141355021-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Lung - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 15: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 28: Astrocytes - Homeostasis & neuron support" 3 "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: , HPA010580: " "unprognostic (8.90e-3)" "unprognostic (1.98e-1)" "unprognostic (1.78e-1)" "unprognostic (7.60e-2)" "unprognostic (1.18e-1)" "potential prognostic favorable (1.32e-4)" "unprognostic (1.77e-1)" "unprognostic (2.41e-2)" "unprognostic (2.13e-1)" "unprognostic (3.20e-1)" "unprognostic (2.58e-2)" "unprognostic (8.79e-3)" "unprognostic (2.68e-1)" "unprognostic (1.50e-1)" "unprognostic (1.04e-1)" "unprognostic (8.85e-2)" PCDHGA5 "CDH-GAMMA-A5, ME3, PCDH-GAMMA-A5" ENSG00000253485 "Protocadherin gamma subfamily A, 5" Q9Y5G8 5 141364162-141512975 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 8.2;Bergmann glia: 6.4;Brain excitatory neurons: 3.1;Brain inhibitory neurons: 2.8;Choroid plexus epithelial cells: 2.7;Ependymal cells: 3.9;Oligodendrocyte progenitor cells: 5.2;Oligodendrocytes: 1.9;Other brain neurons: 1.7" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in some" 4 "Prostate Adenocarcinoma (TCGA): 5.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Fibroblasts_1, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 28: Astrocytes - Homeostasis & neuron support" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: , HPA010580: " "unprognostic (2.01e-2)" "unprognostic (2.54e-2)" "unprognostic (2.83e-1)" "unprognostic (2.22e-2)" "unprognostic (1.37e-1)" "unprognostic (4.14e-3)" "unprognostic (4.60e-1)" "unprognostic (5.37e-2)" "unprognostic (5.97e-3)" "unprognostic (1.75e-2)" "unprognostic (4.94e-2)" "unprognostic (7.31e-3)" PCDHGA6 PCDH-GAMMA-A6 ENSG00000253731 "Protocadherin gamma subfamily A, 6" Q9Y5G7 5 141373891-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 9.6;Bergmann glia: 10.6;Brain excitatory neurons: 3.9;Brain inhibitory neurons: 3.5;Choroid plexus epithelial cells: 6.3;Ependymal cells: 7.2;Oligodendrocyte progenitor cells: 6.5;Oligodendrocytes: 3.7;Other brain neurons: 2.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 28: Astrocytes - Homeostasis & neuron support" "Nucleoplasm, Plasma membrane" "Vesicles, Cytosol" "HPA008755: , HPA010580: " "unprognostic (7.48e-3)" "unprognostic (4.04e-2)" "unprognostic (2.46e-1)" "unprognostic (1.18e-1)" "unprognostic (1.48e-1)" "unprognostic (4.58e-2)" "unprognostic (4.21e-2)" "unprognostic (1.47e-1)" "unprognostic (4.37e-3)" "unprognostic (9.00e-2)" "unprognostic (1.44e-2)" "unprognostic (1.10e-1)" "unprognostic (1.72e-2)" "unprognostic (1.48e-2)" "unprognostic (6.05e-2)" "unprognostic (1.14e-2)" "unprognostic (9.03e-3)" "unprognostic (1.08e-1)" "unprognostic (7.44e-2)" "unprognostic (2.42e-1)" "unprognostic (6.26e-2)" "unprognostic (1.97e-1)" PCDHGA7 PCDH-GAMMA-A7 ENSG00000253537 "Protocadherin gamma subfamily A, 7" Q9Y5G6 5 141382739-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 3.9" "Cell type enhanced" "Detected in some" "Astrocytes: 1.8;Bergmann glia: 1.8;Choroid plexus epithelial cells: 1.3;Ependymal cells: 2.2;Oligodendrocyte progenitor cells: 1.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Fibroblasts_1, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 15: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 28: Astrocytes - Homeostasis & neuron support" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: , HPA010580: " "unprognostic (8.03e-2)" "unprognostic (1.17e-1)" "unprognostic (3.13e-1)" "unprognostic (2.19e-2)" "unprognostic (1.30e-2)" "unprognostic (2.71e-1)" "unprognostic (1.60e-2)" "unprognostic (4.11e-2)" "unprognostic (2.51e-2)" "unprognostic (2.33e-1)" "unprognostic (1.62e-1)" "unprognostic (2.10e-2)" "unprognostic (5.17e-2)" PCDHGA8 "KIAA0327, PCDH-GAMMA-A8" ENSG00000253767 "Protocadherin gamma subfamily A, 8" Q9Y5G5 5 141390157-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 15: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: , HPA010580: " "unprognostic (4.02e-1)" "unprognostic (7.29e-2)" "unprognostic (1.83e-2)" "unprognostic (1.74e-2)" "unprognostic (2.96e-2)" "unprognostic (2.03e-2)" "unprognostic (2.97e-1)" PCDHGA9 PCDH-GAMMA-A9 ENSG00000261934 "Protocadherin gamma subfamily A, 9" Q9Y5G4 5 141402778-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 1.7;Bergmann glia: 1.4;Choroid plexus epithelial cells: 2.1;Ependymal cells: 1.3;Oligodendrocyte progenitor cells: 1.9" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Glioblastoma Multiforme (TCGA): 10.3;Kidney Renal Clear Cell Carcinoma (TCGA): 3.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adrenal gland - Adrenal cortex cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 15: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 22: Non-specific - Basic cellular functions" 1 "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: , HPA010580: " "unprognostic (3.92e-2)" "unprognostic (1.74e-1)" "unprognostic (7.50e-2)" "unprognostic (3.96e-2)" "unprognostic (3.53e-1)" "potential prognostic favorable (7.32e-6)" "unprognostic (8.15e-2)" "unprognostic (1.12e-1)" "unprognostic (4.36e-3)" "unprognostic (9.14e-3)" "unprognostic (6.29e-2)" "unprognostic (1.97e-1)" "unprognostic (5.08e-2)" "unprognostic (1.18e-1)" "unprognostic (1.77e-2)" "unprognostic (1.05e-1)" "unprognostic (3.21e-2)" "unprognostic (2.62e-1)" "unprognostic (4.32e-2)" "unprognostic (1.97e-1)" PCDHGB1 PCDH-GAMMA-B1 ENSG00000254221 "Protocadherin gamma subfamily B, 1" Q9Y5G3 5 141350099-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 11.9" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Bergmann glia: 1.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 7.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA076182" Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane,Focal adhesion sites,Midbody" Yes No "Cluster 73: Brain - Neuronal signaling" "Cluster 39: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 28: Astrocytes - Homeostasis & neuron support" "Vesicles, Plasma membrane" "Nucleoplasm, Focal adhesion sites, Midbody" "HPA008755: , HPA010580: , HPA076182: " "potential prognostic unfavorable (3.30e-4)" "unprognostic (1.12e-2)" "unprognostic (1.45e-1)" "unprognostic (2.27e-1)" "unprognostic (1.30e-1)" "unprognostic (1.75e-1)" "unprognostic (1.30e-2)" "unprognostic (2.85e-3)" "unprognostic (1.00e-1)" "unprognostic (2.52e-2)" "unprognostic (4.56e-3)" "unprognostic (1.29e-2)" "unprognostic (1.77e-2)" "unprognostic (3.59e-2)" "unprognostic (2.64e-2)" "unprognostic (1.73e-2)" "unprognostic (2.09e-1)" "unprognostic (3.83e-2)" "unprognostic (4.19e-2)" "unprognostic (6.94e-2)" "unprognostic (2.46e-1)" "unprognostic (2.60e-1)" "unprognostic (1.25e-1)" "unprognostic (6.38e-2)" PCDHGB2 PCDH-GAMMA-B2 ENSG00000253910 "Protocadherin gamma subfamily B, 2" Q9Y5G2 5 141359994-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bergmann glia: 1.1;Oligodendrocyte progenitor cells: 1.4" "Cell type enhanced" "Detected in some" "oligodendrocyte precursor cell: 2.1" "Cancer enriched" "Detected in many" 6 "Glioblastoma Multiforme (TCGA): 22.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Fibroblasts_1" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA077526" Uncertain Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 15: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 28: Astrocytes - Homeostasis & neuron support" "Vesicles, Plasma membrane, Cytosol" Nucleoplasm "HPA008755: , HPA010580: , HPA077526: " "unprognostic (1.09e-2)" "unprognostic (2.12e-1)" "unprognostic (2.27e-1)" "unprognostic (1.61e-2)" "unprognostic (4.34e-3)" "unprognostic (1.66e-1)" "unprognostic (1.61e-2)" "unprognostic (3.08e-3)" "unprognostic (5.09e-1)" "unprognostic (3.69e-2)" "unprognostic (1.62e-2)" "unprognostic (7.89e-2)" "unprognostic (3.56e-1)" "unprognostic (2.08e-1)" "unprognostic (1.61e-1)" "unprognostic (1.10e-1)" "unprognostic (7.15e-2)" "unprognostic (8.02e-3)" "unprognostic (3.06e-3)" "unprognostic (3.07e-2)" "unprognostic (2.57e-1)" "unprognostic (1.91e-1)" "unprognostic (2.33e-2)" "unprognostic (6.13e-2)" PCDHGB3 PCDH-GAMMA-B3 ENSG00000262209 "Protocadherin gamma subfamily B, 3" Q9Y5G1 5 141370242-141512975 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in single" "Astrocytes: 1.1" "Cell type enhanced" "Detected in some" "Bergmann glia: 2.9" "Cancer enhanced" "Detected in single" "Glioblastoma Multiforme (TCGA): 2.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "HPA008755, HPA010580, HPA035822, HPA035823" Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 70: Non-specific - Protein processing" "Cluster 15: Non-specific - Transcription" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 28: Astrocytes - Homeostasis & neuron support" "Plasma membrane" "Nucleoplasm, Vesicles, Cytosol" "HPA008755: , HPA010580: , HPA035822: , HPA035823: " "unprognostic (1.58e-1)" "unprognostic (1.08e-1)" "unprognostic (9.39e-2)" "unprognostic (9.12e-2)" "unprognostic (5.20e-3)" "unprognostic (3.95e-2)" "unprognostic (3.78e-2)" PCDHGB4 "CDH20, FIB2, PCDH-GAMMA-B4" ENSG00000253953 "Protocadherin gamma subfamily B, 4" Q9UN71 5 141387698-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 9.0;Bergmann glia: 9.2;Brain excitatory neurons: 4.0;Brain inhibitory neurons: 3.6;Choroid plexus epithelial cells: 6.3;Ependymal cells: 6.2;Oligodendrocyte progenitor cells: 7.5;Oligodendrocytes: 3.1;Other brain neurons: 2.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 9.7;testis cancer: 14.2" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 28: Liver & Adrenal gland - Secretion" "Cluster 25: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 28: Astrocytes - Homeostasis & neuron support" "Nucleoplasm, Plasma membrane" "Vesicles, Cytosol" "HPA008755: , HPA010580: " "unprognostic (3.70e-1)" "unprognostic (2.68e-1)" "unprognostic (2.74e-1)" "unprognostic (7.46e-2)" "unprognostic (9.50e-2)" "unprognostic (2.02e-1)" "potential prognostic favorable (9.34e-5)" "unprognostic (8.90e-2)" "unprognostic (9.95e-3)" "unprognostic (2.81e-1)" "unprognostic (1.32e-1)" "unprognostic (9.78e-2)" "unprognostic (1.65e-1)" "unprognostic (1.16e-1)" "unprognostic (4.01e-2)" "unprognostic (6.04e-2)" "unprognostic (1.43e-1)" "unprognostic (4.78e-2)" "unprognostic (3.04e-1)" "unprognostic (4.13e-2)" PCDHGB5 PCDH-GAMMA-B5 ENSG00000276547 "Protocadherin gamma subfamily B, 5" Q9Y5G0 5 141397947-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 18.4" "Cell type enhanced" "Detected in some" "Bergmann glia: 1.1;Choroid plexus epithelial cells: 1.7" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 69: Parathyroid gland - Mixed function" "Cluster 44: Non-specific - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 28: Astrocytes - Homeostasis & neuron support" 3 "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: , HPA010580: " "unprognostic (1.25e-1)" "unprognostic (2.27e-2)" "unprognostic (4.43e-2)" "unprognostic (3.92e-2)" "unprognostic (3.03e-1)" "unprognostic (3.52e-1)" "unprognostic (3.49e-1)" "unprognostic (4.25e-1)" "validated prognostic favorable (2.38e-4)" "validated prognostic favorable (3.13e-4)" "unprognostic (2.13e-1)" "unprognostic (9.67e-2)" "unprognostic (4.61e-3)" "unprognostic (3.17e-1)" "unprognostic (2.28e-1)" "unprognostic (1.06e-3)" "unprognostic (2.58e-1)" "unprognostic (2.47e-2)" "unprognostic (3.22e-1)" "unprognostic (3.24e-1)" "unprognostic (3.70e-2)" "unprognostic (1.31e-1)" "unprognostic (3.43e-2)" "unprognostic (1.34e-2)" "unprognostic (3.33e-1)" "unprognostic (2.07e-1)" "unprognostic (1.78e-1)" PCDHGB6 PCDH-GAMMA-B6 ENSG00000253305 "Protocadherin gamma subfamily B, 6" Q9Y5F9 5 141408021-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.7" "Cell type enhanced" "Detected in some" "Astrocytes: 6.1;Bergmann glia: 6.6;Brain excitatory neurons: 2.8;Brain inhibitory neurons: 2.5;Choroid plexus epithelial cells: 5.2;Ependymal cells: 3.5;Microglia: 1.1;Oligodendrocyte progenitor cells: 4.4;Oligodendrocytes: 2.1;Other brain neurons: 2.1" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 7.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adrenal gland - Adrenal cortex cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 65: Brain - Transcription" "Cluster 19: Astrocytes - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 28: Astrocytes - Homeostasis & neuron support" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: , HPA010580: " "unprognostic (1.58e-1)" "unprognostic (1.03e-1)" "unprognostic (3.67e-1)" "unprognostic (2.19e-1)" "unprognostic (1.93e-1)" "unprognostic (2.16e-1)" "unprognostic (4.04e-1)" "unprognostic (3.62e-1)" "unprognostic (3.18e-1)" "unprognostic (2.52e-3)" "unprognostic (1.39e-3)" "unprognostic (2.09e-1)" "unprognostic (1.66e-2)" "unprognostic (1.42e-1)" "unprognostic (1.96e-1)" "unprognostic (3.73e-2)" "unprognostic (1.66e-2)" "unprognostic (1.60e-1)" "unprognostic (2.25e-1)" "unprognostic (9.81e-2)" "unprognostic (1.64e-1)" "unprognostic (7.51e-2)" "unprognostic (1.31e-1)" "unprognostic (2.43e-2)" "unprognostic (3.55e-1)" "unprognostic (2.11e-2)" "unprognostic (3.86e-2)" PCDHGB7 "ME6, PCDH-GAMMA-B7" ENSG00000254122 "Protocadherin gamma subfamily B, 7" Q9Y5F8 5 141417645-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 2.5;Bergmann glia: 2.5;Brain excitatory neurons: 1.1;Choroid plexus epithelial cells: 1.9;Ependymal cells: 1.6;Oligodendrocyte progenitor cells: 1.9" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 23.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 14.2;Rhabdoid: 16.1" "Adrenal gland - Adrenal cortex cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA 4400 "Cluster 73: Brain - Neuronal signaling" "Cluster 15: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 28: Astrocytes - Homeostasis & neuron support" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: , HPA010580: " "unprognostic (4.29e-1)" "unprognostic (8.58e-2)" "unprognostic (7.91e-2)" "unprognostic (8.46e-3)" "unprognostic (8.47e-2)" "unprognostic (2.07e-1)" "unprognostic (1.68e-1)" "unprognostic (2.74e-1)" "unprognostic (1.62e-1)" "unprognostic (4.92e-3)" "unprognostic (1.61e-1)" "unprognostic (2.65e-1)" "unprognostic (1.14e-2)" "unprognostic (8.49e-2)" "unprognostic (3.08e-1)" "unprognostic (8.18e-3)" "unprognostic (6.96e-2)" "unprognostic (4.73e-2)" "unprognostic (5.48e-2)" "unprognostic (2.88e-2)" "unprognostic (1.85e-2)" "unprognostic (3.06e-2)" "unprognostic (2.90e-2)" "unprognostic (4.24e-3)" "unprognostic (5.42e-3)" "unprognostic (1.86e-2)" "unprognostic (4.62e-1)" "unprognostic (1.68e-1)" "unprognostic (3.24e-2)" PCDHGC3 "PC-43, PC43, PCDH-GAMMA-C3, PCDH2" ENSG00000240184 "Protocadherin gamma subfamily C, 3" Q9UN70 5 141475947-141512977 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 360.0" "Cell type enhanced" "Detected in some" "Astrocytes: 217.1;Bergmann glia: 176.5;Brain excitatory neurons: 62.2;Brain inhibitory neurons: 72.2;Choroid plexus epithelial cells: 39.0;Ependymal cells: 95.4;Oligodendrocyte progenitor cells: 446.1;Oligodendrocytes: 57.6;Other brain neurons: 39.0" "Cell type enhanced" "Detected in all" "oligodendrocyte precursor cell: 464.9" "Group enriched" "Detected in all" 6 "Glioblastoma Multiforme (TCGA): 675.8;Skin Cutaneous Melanoma (TCGA): 239.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 25 "plasmacytoid DC: 15.3" "Lineage enriched" "Detected in single" 25 "dendritic cells: 15.3" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells, Breast - Fibroblasts, Liver - Vascular endothelial cells, Lung - Fibroblasts_1, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA077289" Approved Approved "Plasma membrane" NA NA 1200000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 78: Brain - Neuronal signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 1 "Plasma membrane" "HPA008755: , HPA010580: , HPA077289: " "unprognostic (1.10e-2)" "unprognostic (3.19e-1)" "unprognostic (1.43e-1)" "potential prognostic unfavorable (9.03e-5)" "unprognostic (1.15e-3)" "unprognostic (9.38e-2)" "unprognostic (1.26e-1)" "unprognostic (2.08e-2)" "unprognostic (7.19e-3)" "unprognostic (2.63e-2)" "unprognostic (4.53e-2)" "unprognostic (8.93e-2)" "unprognostic (1.10e-2)" "potential prognostic favorable (6.70e-4)" "unprognostic (1.17e-2)" "unprognostic (5.63e-3)" "unprognostic (2.64e-1)" "unprognostic (1.65e-2)" "unprognostic (1.54e-1)" "unprognostic (1.25e-2)" "potential prognostic unfavorable (2.05e-5)" "unprognostic (2.38e-2)" "unprognostic (1.54e-1)" "unprognostic (7.46e-2)" "potential prognostic unfavorable (6.52e-4)" "unprognostic (5.86e-2)" "unprognostic (3.38e-2)" "unprognostic (1.49e-2)" "unprognostic (5.69e-2)" "unprognostic (1.40e-1)" "unprognostic (1.34e-1)" PCDHGC4 PCDH-GAMMA-C4 ENSG00000242419 "Protocadherin gamma subfamily C, 4" Q9Y5F7 5 141484997-141512975 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 17.3;retina: 6.0" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "Glioblastoma Multiforme (TCGA): 16.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Neuroblastoma: 3.1;testis cancer: 9.0" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 44: Non-specific - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: , HPA010580: " "unprognostic (1.76e-2)" "unprognostic (1.08e-1)" "unprognostic (1.01e-1)" "unprognostic (3.49e-2)" "unprognostic (1.83e-2)" "unprognostic (6.72e-2)" PCDHGC5 PCDH-GAMMA-C5 ENSG00000240764 "Protocadherin gamma subfamily C, 5" Q9Y5F6 5 141489081-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 28.2" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Glioblastoma Multiforme (TCGA): 9.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 4.4;testis cancer: 6.8" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA076140" Supported Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: , HPA010580: , HPA076140: " "unprognostic (9.29e-3)" "unprognostic (1.35e-1)" "unprognostic (1.14e-1)" "unprognostic (1.27e-1)" "unprognostic (6.36e-3)" "unprognostic (3.31e-3)" PCED1A "bA12M19.1, C20orf81, FAM113A, FLJ22376" ENSG00000132635 "PC-esterase domain containing 1A" Q9H1Q7 20 2835314-2841190 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050816 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 64: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 108: Fibroblasts - ECM organization" 8 "Nucleoplasm, Cytosol" "HPA050816: " "unprognostic (6.56e-3)" "unprognostic (1.89e-1)" "unprognostic (1.42e-1)" "unprognostic (1.25e-2)" "unprognostic (1.56e-1)" "unprognostic (1.39e-1)" "unprognostic (1.62e-1)" "potential prognostic favorable (1.40e-4)" "unprognostic (3.34e-1)" "potential prognostic unfavorable (9.89e-6)" "unprognostic (2.20e-1)" "unprognostic (3.90e-2)" "potential prognostic unfavorable (7.37e-4)" "unprognostic (7.17e-2)" "unprognostic (2.07e-2)" "unprognostic (3.11e-1)" "unprognostic (1.61e-1)" "unprognostic (1.17e-1)" "unprognostic (3.60e-2)" "potential prognostic favorable (9.59e-5)" "potential prognostic unfavorable (8.77e-5)" "unprognostic (1.39e-1)" "unprognostic (3.07e-2)" "unprognostic (2.03e-2)" "unprognostic (6.18e-2)" "unprognostic (7.22e-2)" "unprognostic (1.60e-1)" "unprognostic (1.38e-1)" "unprognostic (1.24e-1)" PCED1B "FAM113B, MGC16044" ENSG00000179715 "PC-esterase domain containing 1B" Q96HM7 12 47079603-47236662 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 38.9;lymphoid tissue: 33.7" "Cell type enhanced" "Detected in many" "Adipocytes: 350.8;Adrenal cortex cells: 248.2;Podocytes: 631.1;Renal collecting duct intercalated cells: 238.8;T-cells: 274.4" "Cell type enhanced" "Detected in all" "leukocyte: 404.8" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 39.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - T-cells, Testis - Sertoli cells, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA043901 Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 9: T-cells - Adaptive immunity: Regulation" 4 "Golgi apparatus" Vesicles "HPA043901: " "unprognostic (5.74e-2)" "unprognostic (4.42e-2)" "unprognostic (2.57e-1)" "unprognostic (1.74e-2)" "unprognostic (1.95e-1)" "unprognostic (2.98e-1)" "unprognostic (1.86e-1)" "unprognostic (2.43e-1)" "unprognostic (1.78e-1)" "unprognostic (2.14e-2)" "unprognostic (2.55e-1)" "unprognostic (2.22e-2)" "unprognostic (5.84e-2)" "unprognostic (1.14e-3)" "unprognostic (2.45e-1)" "unprognostic (7.12e-2)" "unprognostic (4.28e-2)" "unprognostic (1.21e-1)" "unprognostic (3.55e-2)" "unprognostic (9.64e-2)" "unprognostic (1.33e-1)" "unprognostic (9.08e-2)" "unprognostic (1.72e-1)" "unprognostic (1.75e-2)" "unprognostic (6.06e-3)" "unprognostic (3.40e-2)" "unprognostic (2.69e-1)" "unprognostic (3.86e-2)" "unprognostic (1.13e-1)" PCF11 KIAA0824 ENSG00000165494 "PCF11 cleavage and polyadenylation factor subunit" O94913 11 83156988-83187451 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 308.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pancreas - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040779 Supported Nucleoplasm,Mitochondria NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 20: Non-specific - Transcription regulation" 19 Nucleoplasm Mitochondria "HPA040779: " "unprognostic (1.69e-1)" "unprognostic (2.49e-2)" "unprognostic (5.94e-3)" "unprognostic (3.90e-2)" "unprognostic (1.59e-1)" "unprognostic (3.46e-1)" "unprognostic (4.64e-3)" "unprognostic (3.22e-3)" "unprognostic (4.53e-3)" "unprognostic (9.30e-2)" "potential prognostic favorable (1.16e-5)" "unprognostic (1.60e-3)" "unprognostic (8.48e-2)" "unprognostic (1.03e-2)" "unprognostic (9.53e-2)" "unprognostic (2.24e-2)" "unprognostic (2.47e-1)" "unprognostic (2.64e-1)" "unprognostic (1.95e-1)" "unprognostic (1.16e-2)" "unprognostic (3.11e-1)" "unprognostic (4.93e-2)" "unprognostic (5.47e-2)" "unprognostic (3.06e-2)" "unprognostic (1.31e-3)" "unprognostic (1.35e-1)" "unprognostic (4.15e-2)" "unprognostic (7.92e-2)" "unprognostic (4.21e-1)" "unprognostic (4.28e-2)" "unprognostic (2.27e-1)" PCGF1 "MGC10882, NSPC1, RNF68" ENSG00000115289 "Polycomb group ring finger 1" Q9BSM1 2 74505043-74507695 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 30.7;Late primary spermatocytes: 36.4;Oocytes: 50.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011356, HPA069156" Supported Enhanced Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 54: Non-specific - Ribosome" "Cluster 31: Non-specific - Transcription" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 41: Oocytes - Oogenesis" 47 Nucleoplasm "HPA011356: , HPA069156: " "unprognostic (1.46e-1)" "unprognostic (5.05e-2)" "unprognostic (4.66e-2)" "unprognostic (1.75e-2)" "unprognostic (1.07e-1)" "unprognostic (3.63e-1)" "unprognostic (3.77e-1)" "unprognostic (1.36e-1)" "unprognostic (5.13e-2)" "unprognostic (1.05e-1)" "unprognostic (9.68e-2)" "unprognostic (9.10e-2)" "unprognostic (7.44e-2)" "unprognostic (2.18e-2)" "unprognostic (1.21e-1)" "unprognostic (4.30e-2)" "unprognostic (3.64e-2)" "unprognostic (4.70e-2)" "unprognostic (7.65e-2)" "unprognostic (1.29e-1)" "unprognostic (4.72e-2)" "unprognostic (2.60e-1)" "unprognostic (6.01e-3)" "unprognostic (1.52e-1)" "unprognostic (1.79e-1)" "unprognostic (1.87e-1)" "unprognostic (1.13e-1)" "unprognostic (1.34e-1)" "unprognostic (8.70e-2)" "unprognostic (1.25e-1)" "unprognostic (1.74e-1)" PCGF2 "MEL-18, RNF110, ZNF144" ENSG00000277258 "Polycomb group ring finger 2" P35227 17 38733898-38749817 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 9.8;Brain inhibitory neurons: 10.3;Choroid plexus epithelial cells: 11.9;Distal convoluted tubule cells: 11.2;Ependymal cells: 20.6;Loop of henle epithelial cells: 16.7;Oligodendrocyte progenitor cells: 18.5;Other brain neurons: 10.8;Papillary tip epithelial cells: 17.0;Podocytes: 8.8;Proximal tubule cells: 22.7;Renal collecting duct intercalated cells: 12.0;Renal collecting duct principal cells: 17.6;Renal connecting tubule cells: 14.2" "Cell type enhanced" "Detected in all" "endothelial cell: 46.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047732, HPA063531" Uncertain Supported Nucleoplasm NA NA "Cluster 64: Non-specific - Transcription" "Cluster 23: Choroid plexus - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 102: Non-specific - Mixed function" 64 Nucleoplasm "HPA047732: , HPA063531: " "unprognostic (1.29e-1)" "unprognostic (3.24e-1)" "unprognostic (5.63e-3)" "unprognostic (4.20e-2)" "unprognostic (9.66e-3)" "unprognostic (1.05e-1)" "unprognostic (3.89e-2)" "potential prognostic unfavorable (1.99e-4)" "unprognostic (2.10e-1)" "unprognostic (8.44e-3)" "potential prognostic favorable (5.25e-4)" "unprognostic (1.38e-3)" "unprognostic (8.51e-3)" "potential prognostic unfavorable (3.60e-5)" "unprognostic (1.35e-2)" "unprognostic (1.88e-1)" "unprognostic (2.81e-1)" "unprognostic (6.03e-3)" "unprognostic (2.44e-1)" "unprognostic (1.09e-1)" "unprognostic (5.30e-2)" "potential prognostic unfavorable (3.13e-4)" "unprognostic (1.64e-1)" "unprognostic (1.60e-1)" "unprognostic (1.29e-2)" "unprognostic (5.73e-1)" "unprognostic (5.56e-2)" "unprognostic (1.41e-1)" PCGF3 "DONG1, FLJ36550, MGC40413, RNF3, RNF3A" ENSG00000185619 "Polycomb group ring finger 3" Q3KNV8 4 705748-770089 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epicardial cells: 188.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061879 Approved Supported Nucleoplasm NA NA "Cluster 32: Basophils - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 43 Nucleoplasm "HPA061879: " "unprognostic (8.21e-2)" "unprognostic (2.71e-2)" "unprognostic (2.25e-1)" "unprognostic (1.78e-2)" "unprognostic (1.25e-1)" "unprognostic (5.60e-3)" "unprognostic (5.97e-2)" "unprognostic (3.16e-2)" "unprognostic (1.06e-1)" "unprognostic (2.48e-1)" "unprognostic (8.00e-3)" "unprognostic (8.18e-3)" "unprognostic (4.08e-1)" "unprognostic (2.16e-3)" "unprognostic (4.93e-2)" "unprognostic (3.54e-3)" "unprognostic (3.37e-3)" "unprognostic (1.35e-1)" "unprognostic (6.09e-3)" "unprognostic (3.21e-1)" "unprognostic (2.00e-2)" "unprognostic (1.43e-2)" "unprognostic (2.31e-2)" "unprognostic (1.56e-2)" "unprognostic (2.21e-1)" "unprognostic (1.83e-2)" "unprognostic (4.94e-2)" "unprognostic (1.20e-1)" "unprognostic (5.11e-1)" "unprognostic (2.05e-1)" "unprognostic (1.02e-1)" PCGF5 "MGC16202, RNF159" ENSG00000180628 "Polycomb group ring finger 5" Q86SE9 10 91163012-91284337 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 633.5;Platelets: 524.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038349, HPA059071" Approved Supported Nucleoplasm NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 61: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 3: Rhabdoid - Membrane components" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 50 Nucleoplasm "HPA038349: , HPA059071: " "unprognostic (1.46e-3)" "unprognostic (1.11e-1)" "unprognostic (5.99e-2)" "unprognostic (1.34e-1)" "unprognostic (4.61e-2)" "unprognostic (1.39e-1)" "unprognostic (1.25e-1)" "unprognostic (5.32e-2)" "unprognostic (5.65e-2)" "unprognostic (4.91e-2)" "validated prognostic favorable (4.74e-9)" "validated prognostic favorable (7.40e-5)" "unprognostic (2.65e-1)" "unprognostic (1.85e-1)" "unprognostic (5.59e-2)" "unprognostic (3.19e-3)" "unprognostic (8.19e-2)" "unprognostic (2.04e-1)" "unprognostic (1.31e-2)" "unprognostic (2.53e-1)" "unprognostic (1.58e-1)" "unprognostic (1.57e-1)" "unprognostic (1.14e-1)" "unprognostic (1.25e-1)" "unprognostic (7.28e-3)" "unprognostic (2.92e-1)" "unprognostic (4.33e-2)" "unprognostic (1.47e-1)" "unprognostic (8.67e-2)" "unprognostic (1.71e-2)" "unprognostic (1.70e-1)" PCGF6 "MBLR, RNF134" ENSG00000156374 "Polycomb group ring finger 6" Q9BYE7 10 103302796-103351144 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 114.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 70: Non-specific - Protein processing" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 3: Early primary spermatocytes - Early meiosis" 57 "unprognostic (1.78e-1)" "unprognostic (3.66e-2)" "unprognostic (1.21e-1)" "unprognostic (1.28e-2)" "unprognostic (1.23e-1)" "unprognostic (8.99e-2)" "unprognostic (2.03e-1)" "potential prognostic favorable (9.89e-4)" "unprognostic (8.17e-2)" "unprognostic (2.26e-1)" "unprognostic (6.22e-2)" "unprognostic (1.16e-1)" "unprognostic (1.36e-2)" "unprognostic (4.69e-2)" "unprognostic (1.38e-1)" "unprognostic (1.15e-2)" "unprognostic (1.72e-2)" "unprognostic (1.27e-2)" "unprognostic (4.77e-3)" "unprognostic (1.46e-1)" "unprognostic (7.64e-2)" "unprognostic (1.06e-1)" "potential prognostic unfavorable (3.76e-4)" "unprognostic (2.21e-1)" "unprognostic (3.24e-3)" "unprognostic (3.87e-1)" "unprognostic (7.62e-2)" "unprognostic (1.65e-1)" "unprognostic (2.20e-1)" "unprognostic (9.08e-3)" "unprognostic (7.93e-2)" PCID2 FLJ11305 ENSG00000126226 "PCI domain containing 2" Q5JVF3 13 113177536-113208715 "Essential proteins, Predicted intracellular proteins" "mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 296.7;Oocytes: 303.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pancreas - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069107, HPA073074" Approved Approved Nucleoplasm,Nucleoli NA Yes "Cluster 5: Non-specific - Cell proliferation" "Cluster 39: Testis - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 19: Non-specific - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 14 "Nucleoplasm, Nucleoli" "HPA069107: , HPA073074: " "unprognostic (2.82e-2)" "unprognostic (1.71e-1)" "unprognostic (9.44e-2)" "unprognostic (3.23e-2)" "unprognostic (2.69e-1)" "unprognostic (1.93e-1)" "unprognostic (8.08e-2)" "unprognostic (2.44e-3)" "potential prognostic unfavorable (7.83e-4)" "unprognostic (1.28e-2)" "potential prognostic favorable (9.28e-4)" "unprognostic (7.21e-3)" "unprognostic (2.92e-1)" "validated prognostic unfavorable (4.29e-4)" "validated prognostic unfavorable (1.35e-4)" "unprognostic (5.43e-3)" "unprognostic (5.55e-3)" "unprognostic (3.19e-2)" "unprognostic (2.31e-1)" "unprognostic (2.63e-1)" "unprognostic (2.75e-1)" "unprognostic (1.63e-1)" "unprognostic (2.49e-2)" "unprognostic (9.76e-2)" "unprognostic (5.88e-2)" "unprognostic (3.10e-1)" "unprognostic (1.11e-1)" "unprognostic (1.75e-1)" "unprognostic (1.35e-1)" "unprognostic (1.02e-1)" "unprognostic (1.74e-1)" PCIF1 "bA465L10.1, C20orf67, CAPAM, PPP1R121" ENSG00000100982 "Phosphorylated CTD interacting factor 1" Q9H4Z3 20 45934683-45948023 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049517 Enhanced Supported "Nucleoplasm,Microtubules,Cytokinetic bridge" Yes No "Cluster 41: Basophils - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 2 Nucleoplasm "Microtubules, Cytokinetic bridge" "HPA049517: " "potential prognostic favorable (1.69e-4)" "unprognostic (4.68e-2)" "unprognostic (2.36e-1)" "unprognostic (2.84e-1)" "unprognostic (1.07e-1)" "unprognostic (2.07e-1)" "unprognostic (8.06e-2)" "unprognostic (5.80e-2)" "unprognostic (2.23e-2)" "unprognostic (1.83e-1)" "unprognostic (8.14e-3)" "unprognostic (5.11e-2)" "unprognostic (4.48e-3)" "unprognostic (4.33e-3)" "unprognostic (6.22e-3)" "unprognostic (1.11e-1)" "unprognostic (4.22e-3)" "unprognostic (4.69e-1)" "unprognostic (1.74e-1)" "unprognostic (1.62e-1)" "unprognostic (4.84e-2)" "unprognostic (1.35e-2)" "unprognostic (3.98e-3)" "unprognostic (3.95e-1)" "unprognostic (1.91e-1)" "unprognostic (1.78e-3)" "unprognostic (3.85e-2)" "unprognostic (7.21e-2)" "unprognostic (1.14e-1)" "unprognostic (1.36e-1)" "unprognostic (4.68e-2)" PCK1 PEPCK-C ENSG00000124253 "Phosphoenolpyruvate carboxykinase 1" P35558 20 57561080-57568121 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Gluconeogenesis "Decarboxylase, Kinase, Lyase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 403.6;liver: 643.7" "Group enriched" "Detected in many" 4 "Colonocytes: 723.5;Enterocytes: 2117.1;Hepatocytes: 1464.1" "Group enriched" "Detected in some" 5 "endothelial cell: 28.4;vascular associated smooth muscle cell: 7.3" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 169.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "colorectal cancer: 6.2;Gastric cancer: 3.9" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Minor Salivary Gland - Adipocytes (Minor salivary gland), Skin - Adipocytes (Skin)" "Not detected" "Not detected" "Not detected" "Not detected" "HPA006277, HPA006507, CAB017027" Approved NA NA 410000 "Cluster 16: Liver & Kidney - Metabolism" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 22 "CAB017027: , HPA006277: , HPA006507: " "unprognostic (2.05e-2)" "unprognostic (9.33e-2)" "unprognostic (6.23e-2)" "unprognostic (1.41e-2)" "unprognostic (8.18e-2)" "validated prognostic favorable (4.39e-8)" "validated prognostic favorable (3.72e-5)" "unprognostic (3.23e-3)" "unprognostic (4.53e-3)" "potential prognostic favorable (3.84e-4)" "unprognostic (2.85e-1)" "unprognostic (1.30e-1)" "unprognostic (1.72e-2)" "unprognostic (2.45e-1)" "unprognostic (2.27e-1)" "unprognostic (3.35e-2)" "unprognostic (1.21e-1)" "unprognostic (4.60e-2)" "unprognostic (1.81e-2)" PCK2 "PEPCK, PEPCK2" ENSG00000100889 "Phosphoenolpyruvate carboxykinase 2, mitochondrial" Q16822 14 24094053-24110598 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Gluconeogenesis "Decarboxylase, Lyase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "intestine: 184.6;kidney: 92.5;liver: 366.9" "Cell type enhanced" "Detected in some" "Early spermatids: 11.8;Enterocytes: 41.1;Epididymal efferent duct absorptive cells: 8.3;Hepatocytes: 13.5;Late primary spermatocytes: 12.3;Microglia: 7.7;Paneth cells: 7.7;Papillary tip epithelial cells: 8.0;Proximal tubule cells: 41.0;Renal collecting duct principal cells: 8.7" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 109.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Macrophages, Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB018734, HPA051162, HPA053502" Enhanced Enhanced Mitochondria NA NA 2400000 "Cluster 14: Non-specific - Unknown function" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 88: Proximal tubular cells - Transmembrane transport" 6 Mitochondria "CAB018734: , HPA051162: , HPA053502: " "unprognostic (2.89e-2)" "unprognostic (1.65e-1)" "unprognostic (1.03e-1)" "unprognostic (8.32e-2)" "potential prognostic favorable (6.62e-4)" "unprognostic (1.82e-1)" "unprognostic (4.79e-2)" "unprognostic (7.07e-2)" "unprognostic (5.01e-2)" "unprognostic (1.04e-2)" "potential prognostic favorable (2.12e-7)" "unprognostic (1.71e-2)" "unprognostic (1.38e-1)" "unprognostic (1.36e-3)" "potential prognostic favorable (3.55e-4)" "unprognostic (5.41e-3)" "unprognostic (2.07e-2)" "unprognostic (7.67e-2)" "unprognostic (6.47e-2)" "unprognostic (2.06e-1)" "potential prognostic favorable (2.15e-4)" "unprognostic (3.29e-2)" "unprognostic (1.84e-1)" "unprognostic (5.02e-3)" "unprognostic (1.54e-1)" "unprognostic (3.90e-2)" "unprognostic (5.85e-1)" "unprognostic (3.11e-1)" "unprognostic (2.46e-1)" "unprognostic (7.59e-2)" "unprognostic (9.91e-2)" PCLAF "KIAA0101, NS5ATP9, OEATC-1, p15(PAF), PAF15" ENSG00000166803 "PCNA clamp associated factor" Q15004 15 64364304-64387687 "Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 121.3;lymphoid tissue: 68.7" "Cell type enriched" "Detected in some" 5 "Late spermatids: 164.5" "Cell type enhanced" "Detected in some" "oligodendrocyte: 1.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "T-reg: 23.6" "Lineage enriched" "Detected in many" 4 "T-cells: 23.6" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Kidney - Fibroblasts, Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Late spermatids" "Group enriched" "Detected in some" 6 "basal ganglia: 3.7;white matter: 11.7" "Low region specificity" "Detected in all" HPA047929 Supported Centrosome NA Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 6: Non-specific - Immune response" "Cluster 58: Non-specific - Nuclear processes" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 10 Centrosome "HPA047929: " "unprognostic (6.07e-2)" "unprognostic (2.42e-2)" "unprognostic (2.10e-2)" "unprognostic (1.37e-1)" "unprognostic (2.46e-1)" "unprognostic (9.08e-2)" "unprognostic (6.85e-2)" "unprognostic (9.20e-2)" "potential prognostic unfavorable (3.42e-4)" "validated prognostic unfavorable (1.02e-4)" "validated prognostic unfavorable (1.54e-4)" "potential prognostic unfavorable (2.17e-7)" "potential prognostic unfavorable (1.08e-5)" "potential prognostic unfavorable (1.50e-5)" "unprognostic (1.13e-3)" "unprognostic (5.06e-3)" "unprognostic (1.94e-1)" "unprognostic (5.00e-2)" "unprognostic (2.31e-1)" "potential prognostic unfavorable (9.22e-4)" "unprognostic (3.79e-3)" "unprognostic (8.09e-2)" "unprognostic (1.56e-1)" "unprognostic (1.06e-1)" "unprognostic (1.06e-2)" "unprognostic (4.08e-2)" "unprognostic (2.13e-1)" "unprognostic (1.26e-1)" "unprognostic (1.47e-2)" PCLO "ACZ, DKFZp779G1236, KIAA0559" ENSG00000186472 "Piccolo presynaptic cytomatrix protein" Q9Y6V0 7 82754012-83162930 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Neurodegeneration "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.2;retina: 20.1" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 840.3;Brain excitatory neurons: 953.2;Brain inhibitory neurons: 740.2;Corticotrophs: 740.7;Gonadotrophs: 812.3;Lactotrophs: 865.3;Other brain neurons: 670.5;Proximal tubule cells: 464.7;Retinal amacrine cells: 693.1;Somatotrophs: 550.6;Thyrotrophs: 728.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary gland ductal cells, Pituitary gland - Lactotropes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "HPA015858, HPA029579, CAB079012" Approved Supported Approved "Nuclear speckles,Plasma membrane" NA NA 6400000 "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 35: Non-specific - DNA binding" "Cluster 72: Neuronal - Signal transduction" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 2 "Plasma membrane" "Nuclear speckles" "CAB079012: , HPA015858: , HPA029579: " "unprognostic (3.69e-1)" "unprognostic (3.81e-2)" "unprognostic (2.21e-2)" "unprognostic (1.64e-1)" "unprognostic (1.01e-1)" "unprognostic (8.14e-2)" "unprognostic (1.54e-1)" "unprognostic (1.03e-1)" "unprognostic (6.47e-2)" "unprognostic (7.60e-3)" "potential prognostic favorable (1.16e-4)" "unprognostic (3.09e-2)" "unprognostic (1.17e-2)" "unprognostic (1.31e-1)" "unprognostic (2.02e-1)" "unprognostic (5.14e-2)" "unprognostic (2.84e-1)" "unprognostic (1.92e-1)" "unprognostic (3.57e-2)" "unprognostic (1.56e-1)" "unprognostic (6.89e-2)" "unprognostic (1.41e-1)" "unprognostic (1.87e-2)" "unprognostic (1.34e-2)" "unprognostic (1.54e-1)" "potential prognostic unfavorable (7.96e-5)" "unprognostic (1.08e-1)" PCM1 PTC4 ENSG00000078674 "Pericentriolar material 1" Q15154 8 17922842-18029948 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023370, HPA023374, CAB058695" Enhanced Supported "Microtubules,Primary cilium,Centriolar satellite,Basal body,Cytosol" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 189 "Microtubules, Primary cilium, Centriolar satellite, Basal body" Cytosol "CAB058695: , HPA023370: , HPA023374: " "unprognostic (8.08e-3)" "unprognostic (6.36e-2)" "unprognostic (3.04e-3)" "unprognostic (1.55e-1)" "unprognostic (8.31e-3)" "unprognostic (1.27e-1)" "unprognostic (2.43e-1)" "unprognostic (7.85e-2)" "unprognostic (3.49e-2)" "unprognostic (3.21e-2)" "validated prognostic favorable (2.16e-5)" "validated prognostic favorable (1.77e-4)" "unprognostic (2.66e-2)" "unprognostic (4.38e-2)" "unprognostic (1.18e-1)" "unprognostic (1.76e-2)" "unprognostic (5.31e-2)" "unprognostic (2.65e-1)" "unprognostic (1.09e-1)" "unprognostic (2.03e-1)" "unprognostic (7.84e-3)" "unprognostic (2.17e-1)" "unprognostic (1.19e-1)" "unprognostic (3.54e-1)" "unprognostic (2.92e-2)" "unprognostic (1.09e-3)" "unprognostic (8.36e-2)" "unprognostic (2.49e-1)" "unprognostic (3.22e-1)" "unprognostic (1.33e-1)" "unprognostic (3.03e-1)" PCMT1 ENSG00000120265 "Protein-L-isoaspartate (D-aspartate) O-methyltransferase" P22061 6 149749444-149811420 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 1214.2;Late primary spermatocytes: 414.6;Late spermatids: 616.2;Neutrophil progenitors: 536.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003239 Approved Supported Cytosol No No 2200000 "Cluster 29: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 23 Cytosol "HPA003239: " "unprognostic (3.87e-2)" "validated prognostic unfavorable (5.19e-7)" "validated prognostic unfavorable (5.23e-4)" "unprognostic (1.25e-2)" "unprognostic (1.17e-2)" "unprognostic (1.82e-3)" "unprognostic (1.30e-1)" "unprognostic (9.92e-2)" "potential prognostic unfavorable (2.96e-5)" "unprognostic (2.60e-2)" "potential prognostic favorable (2.67e-6)" "unprognostic (4.64e-2)" "unprognostic (1.88e-1)" "validated prognostic unfavorable (6.85e-6)" "validated prognostic unfavorable (9.76e-4)" "unprognostic (3.22e-2)" "unprognostic (1.12e-1)" "unprognostic (5.01e-3)" "unprognostic (2.49e-1)" "unprognostic (2.02e-2)" "unprognostic (8.26e-3)" "unprognostic (1.69e-1)" "unprognostic (1.14e-2)" "unprognostic (1.57e-1)" "unprognostic (2.67e-2)" "unprognostic (6.42e-2)" "unprognostic (8.57e-2)" "unprognostic (2.45e-1)" "unprognostic (2.68e-1)" "unprognostic (3.82e-2)" "unprognostic (2.38e-1)" PCMTD1 FLJ10883 ENSG00000168300 "Protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1" Q96MG8 8 51817575-51899186 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Myonuclei: 567.4;Neutrophils: 603.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025696, HPA061444" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 1 "Plasma membrane" Nucleoplasm "HPA025696: , HPA061444: " "unprognostic (8.47e-3)" "unprognostic (1.18e-1)" "unprognostic (3.62e-1)" "unprognostic (2.74e-2)" "unprognostic (7.63e-2)" "unprognostic (2.81e-2)" "unprognostic (2.47e-1)" "unprognostic (1.80e-2)" "unprognostic (1.63e-2)" "unprognostic (6.50e-2)" "unprognostic (1.03e-3)" "unprognostic (4.52e-3)" "unprognostic (9.49e-2)" "unprognostic (1.94e-1)" "unprognostic (1.24e-1)" "unprognostic (1.23e-1)" "unprognostic (2.98e-2)" "unprognostic (7.97e-2)" "unprognostic (6.50e-2)" "unprognostic (4.94e-1)" "unprognostic (2.40e-2)" "unprognostic (5.47e-2)" "unprognostic (4.71e-2)" "unprognostic (2.31e-1)" "unprognostic (3.19e-1)" "unprognostic (8.22e-2)" "unprognostic (1.80e-1)" "unprognostic (6.65e-2)" "unprognostic (1.89e-1)" "potential prognostic unfavorable (7.89e-4)" "unprognostic (3.48e-1)" PCMTD2 "C20orf36, FLJ10883" ENSG00000203880 "Protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2" Q9NV79 20 64255695-64304820 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 164.6" "Cell type enhanced" "Detected in many" "Oligodendrocyte progenitor cells: 167.9;Podocytes: 186.3;Retinal pigment epithelial cells: 127.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057849 Approved Approved Nucleoplasm,Mitochondria No No "Cluster 11: T-cells - Unknown function" "Cluster 42: Retina - Visual perception" "Cluster 16: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 57: Podocytes - Glomerular filtration" 12 Mitochondria Nucleoplasm "HPA057849: " "unprognostic (3.71e-3)" "unprognostic (1.43e-1)" "unprognostic (7.79e-2)" "unprognostic (6.70e-2)" "unprognostic (1.18e-1)" "unprognostic (2.35e-1)" "unprognostic (5.16e-1)" "unprognostic (3.27e-2)" "unprognostic (4.84e-2)" "unprognostic (3.53e-2)" "potential prognostic favorable (4.21e-6)" "unprognostic (1.84e-3)" "unprognostic (2.53e-1)" "unprognostic (9.67e-2)" "unprognostic (8.93e-2)" "unprognostic (1.34e-2)" "unprognostic (6.23e-2)" "unprognostic (4.42e-2)" "unprognostic (7.75e-2)" "unprognostic (2.82e-2)" "unprognostic (5.89e-2)" "unprognostic (2.53e-2)" "unprognostic (6.56e-2)" "unprognostic (2.68e-2)" "unprognostic (5.79e-2)" "unprognostic (1.90e-2)" "unprognostic (3.32e-1)" "unprognostic (2.43e-1)" "unprognostic (3.45e-2)" "unprognostic (2.04e-2)" "unprognostic (2.09e-1)" PCNA ENSG00000132646 "Proliferating cell nuclear antigen" P12004 20 5114953-5126626 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, Host-virus interaction" DNA-binding "Cancer-related genes, Deafness, Disease variant, Dwarfism, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 361.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 191.3;Early spermatids: 233.2;Erythrocyte progenitors: 361.4;Esophageal basal cells: 217.0;Late primary spermatocytes: 240.5;Migrating cytotrophoblasts: 238.2;Monocyte progenitors: 236.8;Oocytes: 492.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Pancreas - Macrophages, Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000148, HPA030521, HPA030522, HPA030523, CAB080239, CAB080240, CAB080241, CAB080242" Enhanced Enhanced Nucleoplasm No Yes 130000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 27: Non-specific - Cell proliferation" 245 Nucleoplasm "CAB000148: , CAB080239: , CAB080240: , CAB080241: , CAB080242: , HPA030521: , HPA030522: , HPA030523: " "unprognostic (2.49e-1)" "unprognostic (6.13e-2)" "unprognostic (2.63e-2)" "potential prognostic favorable (3.89e-4)" "unprognostic (4.37e-2)" "unprognostic (1.58e-1)" "unprognostic (2.30e-1)" "unprognostic (2.97e-1)" "unprognostic (5.89e-3)" "potential prognostic unfavorable (1.50e-4)" "potential prognostic favorable (4.61e-4)" "unprognostic (3.52e-2)" "potential prognostic unfavorable (7.46e-4)" "unprognostic (1.12e-3)" "potential prognostic unfavorable (4.24e-6)" "potential prognostic unfavorable (7.43e-4)" "unprognostic (7.72e-3)" "unprognostic (2.53e-2)" "unprognostic (2.43e-1)" "unprognostic (1.77e-1)" "unprognostic (9.45e-2)" "unprognostic (6.29e-3)" "unprognostic (4.44e-1)" "unprognostic (7.32e-2)" "unprognostic (2.76e-2)" "unprognostic (6.53e-3)" "unprognostic (1.18e-1)" "unprognostic (1.34e-2)" "unprognostic (9.25e-2)" "unprognostic (3.70e-3)" "unprognostic (1.50e-1)" PCNP ENSG00000081154 "PEST proteolytic signal containing nuclear protein" Q8WW12 3 101574180-101594465 "Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035011, HPA063861" Supported Enhanced "Nucleoplasm,Nuclear bodies" No No 36000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 103: Non-specific - Basic cellular processes" 16 Nucleoplasm "Nuclear bodies" "HPA035011: , HPA063861: " "unprognostic (2.74e-1)" "unprognostic (1.47e-2)" "unprognostic (1.54e-2)" "unprognostic (1.41e-1)" "unprognostic (7.56e-2)" "unprognostic (1.32e-1)" "unprognostic (3.67e-1)" "potential prognostic unfavorable (4.17e-4)" "unprognostic (1.39e-1)" "unprognostic (1.70e-3)" "potential prognostic favorable (1.78e-5)" "unprognostic (1.69e-1)" "unprognostic (1.26e-1)" "potential prognostic unfavorable (6.49e-6)" "unprognostic (1.30e-2)" "unprognostic (1.72e-1)" "unprognostic (4.06e-2)" "unprognostic (2.21e-1)" "unprognostic (1.66e-1)" "unprognostic (2.49e-2)" "unprognostic (1.08e-2)" "unprognostic (2.87e-2)" "potential prognostic unfavorable (8.12e-4)" "unprognostic (5.07e-2)" "unprognostic (3.04e-2)" "unprognostic (2.90e-2)" "unprognostic (2.77e-2)" "unprognostic (5.98e-2)" "unprognostic (8.97e-2)" "unprognostic (8.56e-2)" "unprognostic (1.89e-1)" PCNT "KEN, KIAA0402, PCN, PCNT2, PCNTB, SCKL4" ENSG00000160299 Pericentrin O95613 21 46324124-46445769 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Calmodulin-binding Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "skeletal muscle: 234.7" "Group enriched" "Detected in many" 5 "Myonuclei: 757.7;Thymic myoid cells: 1000.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "HPA016820, HPA019887, HPA032101" Approved Supported "Centriolar satellite,Centrosome,Cytosol,Flagellar centriole,Mid piece" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 27 Centrosome "Centriolar satellite, Cytosol, Flagellar centriole, Mid piece" "HPA016820: , HPA019887: , HPA032101: " "unprognostic (2.12e-1)" "unprognostic (4.08e-2)" "unprognostic (1.85e-2)" "unprognostic (2.06e-1)" "unprognostic (6.96e-2)" "unprognostic (2.76e-1)" "unprognostic (3.62e-1)" "unprognostic (8.48e-2)" "unprognostic (2.82e-2)" "unprognostic (7.85e-2)" "unprognostic (2.64e-1)" "unprognostic (2.90e-1)" "unprognostic (1.77e-2)" "unprognostic (3.65e-3)" "unprognostic (1.35e-2)" "unprognostic (5.55e-2)" "unprognostic (9.79e-2)" "unprognostic (1.02e-1)" "unprognostic (1.65e-3)" "unprognostic (9.59e-2)" "unprognostic (1.60e-1)" "potential prognostic favorable (2.46e-4)" "unprognostic (6.61e-3)" "unprognostic (5.71e-2)" "unprognostic (1.76e-2)" "unprognostic (1.13e-1)" "unprognostic (2.78e-1)" "unprognostic (2.36e-1)" "unprognostic (2.10e-2)" "unprognostic (1.20e-1)" "unprognostic (3.98e-1)" PCNX1 "KIAA0805, KIAA0995, PCNX, PCNXL1, pecanex" ENSG00000100731 "Pecanex 1" Q96RV3 14 70907405-71115382 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Neutrophils: 4039.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048970, HPA053532" Approved Approved Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 24: Neutrophils - Innate immunity signal integration" Nucleoplasm "HPA048970: , HPA053532: " "unprognostic (2.20e-1)" "unprognostic (3.55e-1)" "unprognostic (2.13e-1)" "unprognostic (2.12e-1)" "unprognostic (1.24e-1)" "unprognostic (6.84e-2)" "unprognostic (1.99e-2)" "unprognostic (8.87e-2)" "unprognostic (4.15e-3)" "potential prognostic favorable (6.62e-7)" "unprognostic (2.19e-3)" "unprognostic (9.29e-2)" "unprognostic (3.70e-1)" "unprognostic (2.01e-1)" "unprognostic (2.28e-1)" "unprognostic (3.13e-1)" "unprognostic (9.63e-2)" "unprognostic (1.60e-2)" "potential prognostic unfavorable (1.91e-4)" "unprognostic (2.70e-1)" "unprognostic (3.26e-3)" "unprognostic (1.38e-1)" "unprognostic (1.78e-1)" "unprognostic (5.41e-2)" "unprognostic (1.41e-1)" "unprognostic (1.69e-2)" "unprognostic (1.54e-1)" "unprognostic (1.37e-2)" "unprognostic (8.36e-2)" PCNX2 "FLJ11383, KIAA0435, PCNXL2" ENSG00000135749 "Pecanex 2" A6NKB5 1 232983435-233295725 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.1" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 380.0;Lactotrophs: 432.9;Microglia: 601.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013815, HPA014427" Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 51: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" "Endoplasmic reticulum" "HPA013815: , HPA014427: " "unprognostic (1.38e-1)" "unprognostic (7.33e-2)" "unprognostic (7.49e-3)" "unprognostic (2.49e-1)" "unprognostic (3.86e-1)" "unprognostic (3.96e-1)" "unprognostic (2.25e-2)" "unprognostic (2.02e-1)" "unprognostic (2.40e-1)" "potential prognostic unfavorable (1.97e-5)" "unprognostic (4.56e-2)" "unprognostic (7.12e-2)" "unprognostic (3.30e-3)" "unprognostic (7.65e-3)" "unprognostic (3.31e-2)" "unprognostic (6.53e-2)" "unprognostic (1.36e-1)" "unprognostic (4.39e-1)" "unprognostic (2.32e-2)" "unprognostic (2.63e-1)" "unprognostic (9.84e-2)" "unprognostic (4.68e-1)" "unprognostic (1.53e-1)" "unprognostic (2.48e-2)" "unprognostic (1.58e-2)" "unprognostic (2.18e-2)" "unprognostic (1.12e-1)" "unprognostic (2.62e-2)" "unprognostic (2.11e-1)" PCNX3 "FLJ22427, PCNXL3" ENSG00000197136 "Pecanex 3" Q9H6A9 11 65615776-65637439 "Essential proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018084 Uncertain Approved Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 49: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 24: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 9 Cytosol "HPA018084: " "unprognostic (3.53e-1)" "unprognostic (7.27e-3)" "unprognostic (7.51e-3)" "unprognostic (1.97e-2)" "unprognostic (1.72e-1)" "unprognostic (1.69e-1)" "unprognostic (1.75e-1)" "unprognostic (2.94e-3)" "unprognostic (7.17e-3)" "potential prognostic favorable (1.52e-4)" "unprognostic (2.03e-1)" "unprognostic (1.04e-1)" "unprognostic (3.36e-2)" "unprognostic (3.40e-2)" "unprognostic (1.65e-2)" "unprognostic (2.06e-1)" "unprognostic (2.21e-1)" "unprognostic (1.33e-3)" "unprognostic (2.30e-2)" "unprognostic (3.47e-1)" "unprognostic (3.04e-2)" "unprognostic (1.79e-1)" "unprognostic (1.43e-2)" "unprognostic (9.34e-2)" "unprognostic (1.39e-1)" "unprognostic (6.94e-2)" "unprognostic (1.70e-1)" "unprognostic (2.58e-2)" "unprognostic (1.27e-1)" PCNX4 "C14orf135, PCNXL4" ENSG00000126773 "Pecanex 4" Q63HM2 14 60091911-60169133 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Renal collecting duct intercalated cells: 415.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002076, HPA003390" Uncertain Approved Cytosol NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 103: Non-specific - Basic cellular processes" 1 Cytosol "HPA002076: , HPA003390: " "unprognostic (6.94e-2)" "unprognostic (4.79e-2)" "unprognostic (5.80e-2)" "unprognostic (1.29e-1)" "unprognostic (1.54e-1)" "unprognostic (2.30e-1)" "unprognostic (1.39e-1)" "unprognostic (1.42e-1)" "unprognostic (5.01e-2)" "potential prognostic favorable (3.25e-6)" "unprognostic (1.70e-2)" "unprognostic (1.04e-1)" "unprognostic (3.12e-2)" "unprognostic (9.93e-2)" "unprognostic (1.09e-1)" "unprognostic (1.36e-1)" "unprognostic (2.35e-1)" "unprognostic (6.90e-2)" "unprognostic (1.20e-1)" "unprognostic (7.67e-2)" "unprognostic (2.03e-3)" "unprognostic (1.37e-1)" "unprognostic (1.86e-1)" "unprognostic (2.29e-1)" "unprognostic (1.23e-2)" "unprognostic (2.22e-1)" "unprognostic (3.68e-1)" "unprognostic (5.53e-3)" "unprognostic (1.96e-1)" PCOLCE "PCPE, PCPE1" ENSG00000106333 "Procollagen C-endopeptidase enhancer" Q15113 7 100602363-100608175 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 5 "Decidual stromal cells: 2746.3" "Cell type enriched" "Detected in many" 6 "fibroblast: 156.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 209.7;Neuroblastoma: 253.8;Sarcoma: 172.1" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblasts_2, Pituitary gland - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblasts_1, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 106.9" "CAB017623, HPA042927" Approved Approved "Golgi apparatus,Vesicles" "Secreted to extracellular matrix" "No annotated function" NA NA 320000000 "Cluster 35: Non-specific - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 3 "Golgi apparatus, Vesicles" "CAB017623: , HPA042927: " "unprognostic (9.81e-2)" "unprognostic (2.84e-1)" "unprognostic (3.73e-2)" "unprognostic (7.30e-3)" "unprognostic (6.11e-2)" "unprognostic (1.70e-1)" "unprognostic (2.27e-2)" "unprognostic (3.20e-3)" "unprognostic (6.11e-2)" "unprognostic (8.26e-2)" "unprognostic (9.13e-3)" "unprognostic (5.39e-3)" "potential prognostic unfavorable (3.07e-4)" "unprognostic (1.11e-2)" "unprognostic (5.78e-3)" "unprognostic (9.46e-2)" "unprognostic (8.35e-2)" "unprognostic (4.03e-2)" "unprognostic (2.89e-1)" "unprognostic (1.04e-3)" "unprognostic (1.85e-1)" "unprognostic (1.61e-1)" "unprognostic (1.82e-1)" "unprognostic (5.15e-2)" "unprognostic (6.03e-2)" "unprognostic (3.69e-3)" "potential prognostic unfavorable (2.05e-4)" "unprognostic (3.38e-2)" "unprognostic (6.56e-2)" "unprognostic (2.58e-2)" "unprognostic (8.79e-2)" PCOLCE2 PCPE2 ENSG00000163710 "Procollagen C-endopeptidase enhancer 2" Q9UKZ9 3 142815922-142889206 "Predicted secreted proteins" Heparin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 82.3;blood vessel: 82.2;heart muscle: 136.0" "Cell type enhanced" "Detected in many" "Adipocytes: 432.3;Corticotrophs: 661.1;Cytotrophoblasts: 216.4;Fibro-adipogenic progenitors: 160.1;Fibroblasts: 206.6;Mesothelial cells: 118.3;Migrating cytotrophoblasts: 117.8;Podocytes: 521.1;Syncytiotrophoblasts: 382.6" "Cell type enhanced" "Detected in many" "deep-layer corticothalamic and 6b: 63.2;midbrain-derived inhibitory: 156.5;pericyte: 64.2" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 20.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Fibroblasts, Breast - Adipocytes (Breast), Colon - Fibroblasts, Kidney - Podocytes, Pituitary gland - Corticotropes, Prostate - Fibroblasts, Skin - Fibroblasts_2, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA013203 Uncertain Approved Nucleoplasm,Cytosol "Secreted to extracellular matrix" Other NA NA 2000000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 38: Sub-cortical - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 4 "Nucleoplasm, Cytosol" "HPA013203: " "unprognostic (1.46e-2)" "unprognostic (6.20e-2)" "unprognostic (1.49e-3)" "unprognostic (1.29e-1)" "unprognostic (1.84e-2)" "unprognostic (4.21e-2)" "unprognostic (1.41e-3)" "unprognostic (1.64e-1)" "unprognostic (2.89e-2)" "unprognostic (1.27e-1)" "unprognostic (5.96e-2)" "unprognostic (1.99e-2)" "unprognostic (1.06e-2)" "unprognostic (4.65e-2)" "unprognostic (1.73e-2)" "unprognostic (2.03e-1)" "unprognostic (3.32e-1)" "unprognostic (1.55e-1)" "unprognostic (7.71e-2)" "unprognostic (1.65e-1)" "unprognostic (1.08e-2)" "unprognostic (2.18e-1)" "unprognostic (5.68e-2)" "potential prognostic unfavorable (4.00e-5)" "unprognostic (2.34e-1)" PCP2 "GPSM4, MGC41903" ENSG00000174788 "Purkinje cell protein 2" Q8IVA1 19 7631611-7633719 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 111.4;retina: 31.1;testis: 110.8" "Cell type enriched" "Detected in many" 6 "Late spermatids: 6837.6" "Cell type enhanced" "Detected in some" "Bergmann glia: 4.1;leukocyte: 1.3" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in all" 5 "cerebellum: 115.1;white matter: 36.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Leukemia: 4.9" "Breast - Breast glandular cells, Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Testis - Late spermatids" "Region enriched" "Detected in many" 44 "cerebellum: 2160.1" "Region enriched" "Detected in all" 25 "cerebellum: 324.4" HPA057428 Approved "Nuclear speckles,Vesicles" Yes NA "Cluster 35: Neutrophils - Protein binding" "Cluster 67: Testis - Mixed function" "Cluster 35: Non-specific - DNA binding" "Cluster 27: Breast cancer - Unknown function" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 4 "Nuclear speckles" Vesicles "HPA057428: " "unprognostic (9.73e-2)" "unprognostic (2.71e-3)" "unprognostic (7.86e-2)" "potential prognostic favorable (3.27e-4)" "unprognostic (2.56e-2)" "unprognostic (3.45e-2)" "potential prognostic favorable (1.96e-4)" "unprognostic (4.57e-2)" "unprognostic (2.86e-1)" "unprognostic (4.89e-2)" "unprognostic (1.98e-2)" "unprognostic (1.05e-1)" "unprognostic (6.60e-3)" "unprognostic (1.53e-1)" "unprognostic (2.05e-1)" "unprognostic (1.64e-2)" "unprognostic (1.17e-1)" "unprognostic (3.01e-1)" "unprognostic (8.32e-3)" "unprognostic (1.55e-1)" "unprognostic (1.98e-1)" "unprognostic (2.76e-1)" "unprognostic (7.94e-3)" "unprognostic (3.47e-1)" "unprognostic (5.00e-1)" "unprognostic (1.52e-1)" PCP4 PEP-19 ENSG00000183036 "Purkinje cell protein 4" P48539 21 39867438-39929397 "Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 2168.6;choroid plexus: 1406.9;seminal vesicle: 1201.5" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 348.1;Epididymal efferent duct absorptive cells: 455.1;Epididymal efferent duct ciliated cells: 647.6;Epididymal principal cells: 610.5;Retinal bipolar cells: 446.5;Retinal horizontal cells: 1033.7;Retinal pigment epithelial cells: 2157.1;Smooth muscle cells: 1761.7" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 395.4;medium spiny neuron: 451.2;thalamic excitatory: 606.9" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 200.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 72.3;lung cancer: 36.6;Myeloma: 69.4" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Minor Salivary Gland - Smooth muscle cells, Prostate - Smooth muscle cells, Skin - Smooth muscle cells" "Low region specificity" "Detected in all" HPA005792 Enhanced Supported Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 33: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" 27 "Nucleoplasm, Nucleoli fibrillar center" "HPA005792: " "unprognostic (2.21e-3)" "unprognostic (5.40e-2)" "unprognostic (6.38e-2)" "unprognostic (1.54e-3)" "unprognostic (2.69e-2)" "unprognostic (8.93e-2)" "unprognostic (6.13e-2)" "potential prognostic favorable (2.03e-4)" "unprognostic (8.68e-2)" "unprognostic (8.31e-2)" "unprognostic (1.99e-2)" "unprognostic (1.91e-2)" "potential prognostic favorable (2.64e-6)" "unprognostic (4.45e-1)" "unprognostic (2.89e-1)" "unprognostic (1.38e-3)" "unprognostic (2.63e-1)" "unprognostic (1.57e-1)" "unprognostic (2.18e-1)" "unprognostic (1.51e-1)" "unprognostic (3.71e-1)" "unprognostic (1.40e-2)" "unprognostic (1.35e-2)" "unprognostic (6.32e-2)" "unprognostic (4.26e-1)" "unprognostic (6.84e-2)" "unprognostic (8.48e-2)" "unprognostic (5.38e-2)" "unprognostic (1.54e-1)" "unprognostic (1.27e-1)" PCP4L1 IQM1 ENSG00000248485 "Purkinje cell protein 4 like 1" A6NKN8 1 161258745-161285450 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 191.4;pituitary gland: 86.5" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 55.6;Brain inhibitory neurons: 45.6;Breast lactating cells: 37.7;Esophageal apical cells: 28.3;Esophageal suprabasal cells: 33.6;Ocular epithelial cells: 60.7;Oocytes: 36.8;Prostatic hillock cells: 45.5;Respiratory basal cells: 62.4;Retinal bipolar cells: 100.2;Retinal ganglion cells: 30.9;Somatotrophs: 30.3;Urothelial cells: 61.8;Vascular smooth muscle cells: 30.4" "Group enriched" "Detected in many" 4 "cerebellar inhibitory: 54.9;CGE interneuron: 72.6;eccentric medium spiny neuron: 53.2;LAMP5-LHX6 and Chandelier: 72.4;lower rhombic lip: 50.8;medium spiny neuron: 56.6;MGE interneuron: 28.5;midbrain-derived inhibitory: 53.1;splatter: 27.8" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 41.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "thyroid cancer: 3.3" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Heart muscle - Smooth muscle cells, Lung - Alveolar cells type 2, Prostate - Urothelial cells, Skin - Sebaceous gland cells, Testis - Peritubular cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "olfactory bulb: 283.3" HPA052833 Enhanced Supported Approved Nucleoplasm,Mitochondria NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "Nucleoplasm, Mitochondria" "HPA052833: " "unprognostic (2.71e-2)" "unprognostic (1.54e-1)" "unprognostic (4.88e-2)" "unprognostic (1.07e-1)" "unprognostic (3.84e-2)" "unprognostic (1.87e-1)" "unprognostic (2.64e-2)" "unprognostic (2.10e-1)" "unprognostic (2.64e-1)" "unprognostic (1.90e-2)" "potential prognostic favorable (8.40e-6)" "unprognostic (7.86e-2)" "unprognostic (2.47e-2)" "unprognostic (1.38e-1)" "unprognostic (8.40e-2)" "unprognostic (6.29e-2)" "unprognostic (2.86e-1)" "unprognostic (6.73e-2)" "unprognostic (2.84e-1)" "unprognostic (1.89e-1)" "unprognostic (2.31e-2)" PCSK1 "NEC1, PC1, PC1/3, PC3, SPC3" ENSG00000175426 "Proprotein convertase subtilisin/kexin type 1" P29120 5 96390333-96434143 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Disease variant, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 31.0;pituitary gland: 11.4" "Group enriched" "Detected in many" 4 "Cardiomyocytes: 108.3;Corticotrophs: 182.3;Epicardial cells: 111.4;Gonadotrophs: 122.7;Neuroendocrine cells: 204.4;Other brain neurons: 72.5;Pancreatic islet cells: 187.7" "Cell type enhanced" "Detected in many" "deep-layer near-projecting: 55.9" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 21.6" "Region enhanced" "Detected in all" "hypothalamus: 173.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "lung cancer: 27.1;thyroid cancer: 74.8" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA048564, HPA079656" Approved "Secreted in other tissues" Enzyme NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" "HPA048564: , HPA079656: " "unprognostic (6.30e-2)" "unprognostic (4.08e-1)" "unprognostic (2.58e-2)" "unprognostic (2.90e-1)" "potential prognostic unfavorable (1.07e-4)" "unprognostic (5.07e-2)" "unprognostic (3.55e-1)" "unprognostic (7.93e-2)" "unprognostic (6.25e-3)" "unprognostic (2.43e-1)" "unprognostic (9.52e-2)" "unprognostic (1.97e-1)" "unprognostic (3.46e-3)" "unprognostic (1.16e-1)" "unprognostic (9.80e-2)" "unprognostic (9.22e-2)" "unprognostic (4.64e-1)" "unprognostic (1.05e-1)" "unprognostic (8.01e-2)" "unprognostic (4.95e-3)" PCSK1N "BigLEN, PEN, proSAAS, SAAS, SCG8, SgVIII" ENSG00000102109 "Proprotein convertase subtilisin/kexin type 1 inhibitor" Q9UHG2 X 48831096-48835610 "Predicted secreted proteins" Neuropeptide "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 782.7;pituitary gland: 1213.3" "Cell type enhanced" "Detected in many" "Corticotrophs: 1037.9;Epididymal efferent duct ciliated cells: 1180.6;Epididymal principal cells: 767.0;Gonadotrophs: 898.1;Lactotrophs: 528.0;Neuroendocrine cells: 4146.1;Other brain neurons: 886.0;Pancreatic islet cells: 2847.0;Somatotrophs: 502.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "MAIT T-cell: 2.4;memory CD4 T-cell: 5.0;memory CD8 T-cell: 4.9;naive CD4 T-cell: 2.0;naive CD8 T-cell: 6.4;T-reg: 1.8" "Lineage enriched" "Detected in single" 64 "T-cells: 6.4" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Prostate - Prostate glandular cells, Stomach - Gastric enteroendocrine cells, Thyroid gland - Parafollicular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003925, HPA064734" Enhanced Supported Approved Vesicles "Secreted to blood" Neuropeptide NA NA 1300000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 78: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" Vesicles "HPA003925: , HPA064734: " "unprognostic (5.86e-2)" "unprognostic (5.15e-3)" "unprognostic (6.63e-3)" "unprognostic (2.97e-2)" "unprognostic (1.97e-1)" "unprognostic (6.31e-2)" "unprognostic (1.63e-1)" "potential prognostic favorable (3.91e-5)" "unprognostic (5.32e-3)" "unprognostic (1.35e-3)" "unprognostic (6.70e-3)" "unprognostic (4.50e-3)" "unprognostic (6.60e-3)" "unprognostic (1.56e-2)" "unprognostic (1.43e-2)" "unprognostic (3.11e-1)" "unprognostic (8.32e-2)" "unprognostic (8.88e-2)" "unprognostic (4.51e-1)" "unprognostic (3.87e-2)" "unprognostic (1.74e-3)" "unprognostic (9.44e-2)" "unprognostic (8.23e-3)" "unprognostic (4.60e-2)" "unprognostic (1.41e-1)" "unprognostic (2.32e-1)" "unprognostic (3.08e-2)" "unprognostic (3.30e-2)" "unprognostic (2.05e-1)" "unprognostic (7.75e-2)" PCSK2 "NEC2, PC2, SPC2" ENSG00000125851 "Proprotein convertase subtilisin/kexin type 2" P16519 20 17226107-17484578 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 26.9;retina: 33.2;thyroid gland: 54.2" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 882.9;Brain excitatory neurons: 314.9;Brain inhibitory neurons: 285.9;Early spermatids: 149.8;Melanocytes: 450.8;Müller glia: 902.8;Other brain neurons: 255.2;Pancreatic islet cells: 902.6;Retinal ganglion cells: 212.5;Retinal horizontal cells: 320.5" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 5 "Thyroid Carcinoma (TCGA): 212.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 30.0;lung cancer: 15.9;thyroid cancer: 12.7" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Lung - Alveolar cells type 2, Pancreas - Alpha cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049627 Approved Approved Vesicles "Secreted in other tissues" Enzyme NA NA 9100 "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" Vesicles "HPA049627: " "potential prognostic unfavorable (6.50e-4)" "unprognostic (9.57e-2)" "unprognostic (3.15e-1)" "unprognostic (1.46e-2)" "unprognostic (1.78e-2)" "unprognostic (2.30e-3)" "unprognostic (2.36e-3)" "unprognostic (6.42e-3)" "unprognostic (9.81e-2)" "unprognostic (1.81e-1)" "unprognostic (1.76e-3)" "unprognostic (1.58e-1)" "unprognostic (1.79e-1)" "unprognostic (2.35e-1)" PCSK4 "DKFZp434B217, MGC34749, PC4, SPC5" ENSG00000115257 "Proprotein convertase subtilisin/kexin type 4" Q6UW60 19 1481428-1490752 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "testis: 62.5" "Cell type enriched" "Detected in many" 4 "Late spermatids: 1192.2" "Cell type enhanced" "Detected in many" "ependymal cell: 39.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA005572 Uncertain NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 46: Brainstem - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" "HPA005572: " "unprognostic (1.09e-1)" "unprognostic (6.12e-2)" "unprognostic (1.03e-2)" "unprognostic (1.22e-1)" "unprognostic (4.43e-2)" "unprognostic (3.22e-1)" "unprognostic (1.93e-2)" "unprognostic (2.06e-1)" "unprognostic (7.39e-3)" "unprognostic (2.55e-1)" "unprognostic (5.96e-2)" "unprognostic (1.01e-1)" "unprognostic (1.57e-1)" "unprognostic (2.62e-1)" "unprognostic (6.15e-2)" "unprognostic (1.89e-2)" "unprognostic (2.88e-1)" "unprognostic (5.37e-2)" "unprognostic (2.11e-1)" "unprognostic (1.35e-1)" "unprognostic (1.86e-2)" "unprognostic (1.09e-2)" "unprognostic (5.06e-1)" PCSK5 "PC5, PC6, SPC6" ENSG00000099139 "Proprotein convertase subtilisin/kexin type 5" Q92824 9 75890644-76362975 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Pregnancy "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 24.4" "Cell type enhanced" "Detected in many" "Adipocytes: 551.0;Bergmann glia: 701.0;Colonocytes: 577.8;Enterocytes: 1868.4;Esophageal apical cells: 792.8;Ocular epithelial cells: 658.6;Retinal horizontal cells: 675.1;Sertoli cells: 532.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Stomach Adenocarcinoma (TCGA): 31.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD8 T-cell: 4.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Prostate - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA031072 Approved Supported "Golgi apparatus" "Secreted to blood" Enzyme NA NA 5000 "Cluster 33: Non-specific - ATP binding" "Cluster 77: Intestine - Digestion" "Cluster 51: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 1: Enterocytes - Absorption and Digestion" 17 "Golgi apparatus" "HPA031072: " "unprognostic (1.74e-1)" "unprognostic (1.46e-1)" "unprognostic (4.87e-2)" "unprognostic (2.81e-1)" "unprognostic (3.81e-2)" "unprognostic (2.97e-1)" "unprognostic (1.15e-1)" "unprognostic (4.11e-3)" "unprognostic (2.14e-1)" "unprognostic (2.17e-2)" "unprognostic (4.09e-3)" "potential prognostic favorable (6.52e-4)" "potential prognostic unfavorable (4.18e-9)" "unprognostic (5.60e-2)" "unprognostic (2.65e-2)" "unprognostic (1.00e-1)" "unprognostic (1.88e-1)" "unprognostic (1.56e-1)" "unprognostic (1.99e-1)" "unprognostic (1.90e-1)" "unprognostic (2.30e-2)" "unprognostic (4.26e-2)" "unprognostic (2.18e-1)" "unprognostic (1.50e-1)" "unprognostic (4.55e-1)" "unprognostic (1.36e-1)" "unprognostic (6.18e-2)" "unprognostic (1.31e-1)" "unprognostic (2.57e-2)" "unprognostic (3.48e-1)" "unprognostic (9.68e-3)" PCSK6 "PACE4, SPC4" ENSG00000140479 "Proprotein convertase subtilisin/kexin type 6" P29122 15 101289784-101525202 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 108.7;liver: 149.2;lymphoid tissue: 76.5" "Cell type enhanced" "Detected in many" "Bergmann glia: 978.9;Breast lactating cells: 252.4;Hepatocytes: 630.7;Lymphatic endothelial cells: 254.7;Oligodendrocytes: 635.9;Pituitary stem cells: 375.9;Platelets: 341.8;Retinal horizontal cells: 1744.9;Sertoli cells: 257.4" "Group enriched" "Detected in all" 4 "Bergmann glia: 1017.2;oligodendrocyte: 1025.3" "Group enriched" "Detected in many" 4 "Breast Invasive Carcinoma (TCGA): 29.6;Kidney Renal Clear Cell Carcinoma (TCGA): 68.3;Liver Hepatocellular Carcinoma (TCGA): 68.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 3.3" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Liver - Hepatocytes, Skin - Keratinocyte (granular), Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004774 Uncertain "Secreted to extracellular matrix" Enzyme NA NA 1400000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 30: White matter - Myelination" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 80: Oligodendrocytes - Myelination" 1 "HPA004774: " "unprognostic (9.27e-3)" "potential prognostic favorable (8.89e-4)" "unprognostic (3.85e-1)" "unprognostic (1.19e-1)" "unprognostic (3.04e-1)" "unprognostic (1.76e-2)" "unprognostic (1.22e-1)" "unprognostic (2.25e-2)" "unprognostic (1.49e-1)" "unprognostic (1.62e-1)" "potential prognostic favorable (3.55e-4)" "unprognostic (1.31e-1)" "potential prognostic unfavorable (2.77e-4)" "unprognostic (1.87e-2)" "unprognostic (3.05e-2)" "unprognostic (1.02e-1)" "unprognostic (2.15e-2)" "unprognostic (3.73e-1)" "unprognostic (5.81e-3)" "unprognostic (1.58e-2)" "unprognostic (6.73e-2)" "potential prognostic unfavorable (3.82e-4)" "unprognostic (1.70e-2)" "unprognostic (2.18e-1)" "unprognostic (6.31e-2)" "unprognostic (1.29e-2)" "unprognostic (1.55e-1)" "unprognostic (2.23e-1)" "unprognostic (5.03e-1)" "unprognostic (1.99e-1)" PCSK7 "LPC, PC7, PC8, SPC7" ENSG00000160613 "Proprotein convertase subtilisin/kexin type 7" Q16549 11 117204337-117232525 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 152.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 22000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 11: White matter - Signal transduction" "Cluster 24: Non-specific - Unknown function" "Cluster 9: T-cells - Adaptive immunity: Regulation" 9 "unprognostic (3.20e-2)" "potential prognostic unfavorable (7.58e-4)" "unprognostic (3.81e-2)" "unprognostic (5.13e-3)" "unprognostic (9.40e-3)" "unprognostic (1.67e-1)" "unprognostic (1.16e-1)" "unprognostic (1.30e-3)" "unprognostic (3.76e-2)" "unprognostic (4.21e-3)" "unprognostic (3.86e-3)" "unprognostic (3.41e-1)" "unprognostic (1.23e-3)" "unprognostic (1.04e-2)" "unprognostic (7.68e-2)" "unprognostic (1.35e-2)" "unprognostic (1.08e-1)" "unprognostic (2.60e-1)" "unprognostic (2.13e-1)" "unprognostic (5.92e-2)" "unprognostic (9.12e-2)" "unprognostic (1.05e-1)" "unprognostic (1.05e-1)" "unprognostic (9.60e-2)" "unprognostic (2.82e-2)" "unprognostic (4.02e-2)" "unprognostic (6.62e-3)" "unprognostic (3.39e-3)" "unprognostic (1.96e-1)" "unprognostic (1.91e-1)" "unprognostic (2.41e-1)" PCSK9 "FH3, HCHOLA3, NARC-1" ENSG00000169174 "Proprotein convertase subtilisin/kexin type 9" Q8NBP7 1 55039447-55064852 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 47.5" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 5.9;Alveolar cells type 2: 32.4;Esophageal basal cells: 7.8;Esophageal suprabasal cells: 5.9;Gastric progenitor cells: 26.9;Hepatocytes: 21.9;Neutrophil progenitors: 6.0;Neutrophils: 8.9;Transitional alveolar cells: 7.9" "Group enriched" "Detected in some" 5 "lower rhombic lip: 10.3;upper rhombic lip: 8.0" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 6 "cerebellum: 7.1;medulla oblongata: 1.8;pons: 4.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2, Spleen - Neutrophils_2, Stomach - Mitotic cells (Stomach), Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted to blood" Enzyme NA NA 143000000 190000000 "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 37: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 36 "unprognostic (8.78e-3)" "unprognostic (7.09e-2)" "unprognostic (1.22e-1)" "unprognostic (5.39e-1)" "unprognostic (1.00e-1)" "unprognostic (9.55e-2)" "potential prognostic unfavorable (1.70e-4)" "unprognostic (2.23e-1)" "unprognostic (7.23e-3)" "unprognostic (3.63e-2)" "unprognostic (2.03e-1)" "unprognostic (7.04e-3)" "unprognostic (3.53e-3)" "unprognostic (4.80e-2)" "unprognostic (2.25e-1)" "unprognostic (1.28e-1)" "unprognostic (3.51e-2)" "unprognostic (1.13e-1)" "unprognostic (1.20e-1)" "unprognostic (3.15e-1)" PCTP STARD2 ENSG00000141179 "Phosphatidylcholine transfer protein" Q9UKL6 17 55751051-55842830 "Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 91.6" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 93.5;Hepatocytes: 101.2;Neutrophils: 74.4;Platelets: 104.1;Syncytiotrophoblasts: 84.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 241.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA022979 Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 19: Astrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 6 "Nucleoplasm, Nucleoli" "HPA022979: " "unprognostic (5.39e-2)" "unprognostic (1.22e-1)" "unprognostic (7.36e-2)" "unprognostic (2.64e-2)" "unprognostic (1.50e-2)" "unprognostic (1.07e-1)" "unprognostic (3.64e-2)" "unprognostic (1.13e-2)" "potential prognostic unfavorable (1.41e-5)" "unprognostic (9.54e-3)" "potential prognostic favorable (3.20e-6)" "unprognostic (1.73e-2)" "unprognostic (9.16e-2)" "unprognostic (2.11e-2)" "unprognostic (1.61e-2)" "unprognostic (1.39e-1)" "unprognostic (9.56e-2)" "unprognostic (1.84e-2)" "unprognostic (1.42e-1)" "unprognostic (5.47e-2)" "unprognostic (9.28e-3)" "unprognostic (1.99e-3)" "unprognostic (1.56e-1)" "unprognostic (1.11e-1)" "unprognostic (6.56e-2)" "unprognostic (6.31e-2)" "unprognostic (3.59e-1)" "unprognostic (3.85e-2)" "unprognostic (1.97e-1)" "unprognostic (1.37e-2)" "unprognostic (3.44e-3)" PCYOX1 "KIAA0908, PCL1" ENSG00000116005 "Prenylcysteine oxidase 1" Q9UHG3 2 70257386-70281185 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 230.9;Hepatocytes: 219.7;Salivary acinar cells: 180.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Lung - Alveolar cells type 1, Spleen - Fibroblasts_2, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035193 Approved "Intracellular and membrane" Enzyme NA NA 390000000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 26 "HPA035193: " "unprognostic (3.01e-1)" "unprognostic (3.60e-2)" "unprognostic (2.62e-1)" "unprognostic (3.75e-3)" "unprognostic (3.05e-2)" "unprognostic (4.77e-2)" "unprognostic (1.30e-1)" "potential prognostic unfavorable (9.79e-4)" "unprognostic (1.60e-1)" "unprognostic (4.32e-2)" "potential prognostic favorable (1.18e-8)" "unprognostic (5.77e-3)" "unprognostic (2.49e-1)" "unprognostic (1.60e-1)" "unprognostic (3.45e-2)" "unprognostic (1.18e-1)" "unprognostic (2.29e-2)" "unprognostic (2.55e-1)" "unprognostic (2.64e-1)" "unprognostic (2.02e-1)" "unprognostic (1.16e-2)" "unprognostic (8.93e-2)" "unprognostic (1.82e-1)" "unprognostic (8.32e-2)" "unprognostic (2.72e-1)" "unprognostic (3.67e-2)" "unprognostic (1.04e-1)" "unprognostic (1.10e-1)" "unprognostic (1.57e-1)" "unprognostic (6.07e-2)" "unprognostic (3.05e-1)" PCYOX1L MGC3265 ENSG00000145882 "Prenylcysteine oxidase 1 like" Q8NBM8 5 149358037-149369653 "Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oocytes: 27.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037463, HPA038402" Approved Approved Nucleoplasm,Mitochondria "Secreted to blood" Enzyme NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 65: Brain - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 109: Neurons - Neuronal signaling" 8 "Nucleoplasm, Mitochondria" "HPA037463: , HPA038402: " "unprognostic (2.02e-2)" "unprognostic (1.30e-1)" "unprognostic (1.31e-1)" "unprognostic (4.87e-2)" "unprognostic (3.22e-1)" "unprognostic (2.18e-2)" "unprognostic (1.65e-1)" "unprognostic (4.17e-3)" "unprognostic (5.98e-2)" "unprognostic (1.30e-1)" "unprognostic (2.68e-2)" "unprognostic (6.68e-2)" "unprognostic (5.69e-2)" "unprognostic (1.84e-1)" "unprognostic (1.68e-1)" "unprognostic (4.77e-1)" "potential prognostic favorable (8.08e-4)" "unprognostic (3.39e-2)" "unprognostic (1.58e-1)" "unprognostic (8.76e-2)" "potential prognostic favorable (9.22e-4)" "unprognostic (6.27e-2)" "unprognostic (2.26e-1)" "unprognostic (1.11e-2)" "unprognostic (1.80e-1)" "unprognostic (6.12e-2)" "unprognostic (5.61e-2)" "unprognostic (3.07e-1)" "unprognostic (1.21e-2)" "unprognostic (1.80e-1)" PCYT1A "CCTalpha, CT, CTPCT, PCYT1" ENSG00000161217 "Phosphate cytidylyltransferase 1A, choline" P49585 3 196214222-196287957 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Nucleotidyltransferase, Transferase" "Cone-rod dystrophy, Congenital generalized lipodystrophy, Diabetes mellitus, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 196.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035428 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 63: Non-specific - Protein processing" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 19 Nucleoplasm Cytosol "HPA035428: " "unprognostic (3.94e-1)" "unprognostic (8.24e-3)" "unprognostic (3.64e-2)" "unprognostic (7.15e-2)" "unprognostic (1.99e-1)" "unprognostic (3.00e-2)" "unprognostic (7.67e-2)" "unprognostic (5.83e-2)" "unprognostic (1.98e-1)" "unprognostic (1.25e-2)" "unprognostic (5.91e-3)" "unprognostic (2.29e-1)" "unprognostic (2.37e-1)" "potential prognostic unfavorable (2.18e-4)" "unprognostic (2.62e-1)" "unprognostic (2.49e-2)" "unprognostic (1.53e-3)" "unprognostic (8.36e-2)" "unprognostic (5.28e-2)" "unprognostic (1.11e-2)" "unprognostic (8.06e-2)" "unprognostic (4.68e-2)" "unprognostic (6.37e-3)" "unprognostic (3.60e-2)" "unprognostic (1.66e-2)" "unprognostic (7.53e-2)" "unprognostic (1.24e-3)" "unprognostic (1.86e-1)" "unprognostic (2.31e-1)" "unprognostic (6.50e-3)" "unprognostic (3.07e-1)" PCYT1B "CCT-beta, CCTbeta, CTB" ENSG00000102230 "Phosphate cytidylyltransferase 1B, choline" Q9Y5K3 X 24558087-24672677 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.0;retina: 11.2;testis: 12.0" "Cell type enhanced" "Detected in many" "Astrocytes: 43.1;Bergmann glia: 48.3;Choroid plexus epithelial cells: 108.4;Ependymal cells: 63.7;Late spermatids: 156.0;Müller glia: 74.9;Oligodendrocyte progenitor cells: 38.5;Oligodendrocytes: 59.3;Platelets: 146.8;Respiratory ciliated cells: 38.9;Retinal pigment epithelial cells: 63.9;Sertoli cells: 36.4" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 109.1" "Group enriched" "Detected in some" 4 "Glioblastoma Multiforme (TCGA): 7.4;Lung Squamous Cell Carcinoma (TCGA): 2.4;Testicular Germ Cell Tumor (TCGA): 2.3;Uterine Corpus Endometrial Carcinoma (TCGA): 2.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 7.6;testis cancer: 6.5" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Breast - Breast myoepithelial cells, Lung - Respiratory ciliated cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Prostate - Smooth muscle cells, Skin - Outer root sheath cells, Spleen - Smooth muscle cells, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006367 Uncertain NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 47: Platelets - Hemostasis" 2 "HPA006367: " "unprognostic (2.13e-1)" "unprognostic (1.65e-1)" "unprognostic (9.78e-2)" "unprognostic (2.20e-1)" "unprognostic (1.10e-3)" "unprognostic (5.12e-2)" "unprognostic (1.98e-1)" PCYT2 ET ENSG00000185813 "Phosphate cytidylyltransferase 2, ethanolamine" Q99447 17 81900958-81911432 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Nucleotidyltransferase, Transferase" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 163.1;testis: 248.9" "Cell type enriched" "Detected in many" 6 "Late spermatids: 5103.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023033, HPA023034" Enhanced Approved Nucleoplasm,Cytosol NA NA 86000 "Cluster 14: Non-specific - Unknown function" "Cluster 67: Testis - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 8 Cytosol Nucleoplasm "HPA023033: , HPA023034: " "unprognostic (9.25e-2)" "unprognostic (1.37e-2)" "unprognostic (1.86e-1)" "unprognostic (2.19e-1)" "unprognostic (3.84e-2)" "unprognostic (1.69e-1)" "unprognostic (1.52e-1)" "unprognostic (1.62e-1)" "unprognostic (1.64e-1)" "unprognostic (7.61e-2)" "unprognostic (1.54e-2)" "unprognostic (1.22e-1)" "unprognostic (3.96e-3)" "unprognostic (1.41e-3)" "unprognostic (1.75e-1)" "unprognostic (3.79e-1)" "unprognostic (7.76e-2)" "unprognostic (2.82e-2)" "unprognostic (2.89e-3)" "unprognostic (1.62e-2)" "unprognostic (1.76e-3)" "unprognostic (1.06e-1)" "unprognostic (2.13e-1)" "unprognostic (2.73e-1)" "unprognostic (4.57e-2)" "unprognostic (6.58e-2)" "unprognostic (1.39e-1)" "unprognostic (1.69e-1)" "unprognostic (2.09e-1)" "unprognostic (8.10e-2)" "unprognostic (1.46e-1)" PDAP1 "HASPP28, PAP, PAP1" ENSG00000106244 "PDGFA associated protein 1" Q13442 7 99392048-99408597 "Cancer-related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal basal cells: 307.3;Esophageal suprabasal cells: 310.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Inner root sheath cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB021103, HPA050294, HPA060836" Approved Enhanced "Plasma membrane,Cytosol" NA NA 510000 "Cluster 21: Neutrophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 9 Cytosol "Plasma membrane" "CAB021103: , HPA050294: , HPA060836: " "unprognostic (1.55e-2)" "unprognostic (1.20e-1)" "unprognostic (6.95e-3)" "unprognostic (2.10e-2)" "unprognostic (7.59e-2)" "unprognostic (1.35e-2)" "unprognostic (1.28e-2)" "unprognostic (3.33e-2)" "unprognostic (3.15e-2)" "potential prognostic unfavorable (4.71e-5)" "potential prognostic unfavorable (2.11e-4)" "unprognostic (6.66e-3)" "unprognostic (3.56e-1)" "validated prognostic unfavorable (1.72e-4)" "validated prognostic unfavorable (2.06e-6)" "unprognostic (7.15e-3)" "unprognostic (4.63e-3)" "unprognostic (1.15e-3)" "unprognostic (4.96e-2)" "unprognostic (8.35e-2)" "unprognostic (2.34e-2)" "unprognostic (2.70e-1)" "potential prognostic unfavorable (2.04e-4)" "unprognostic (7.75e-2)" "unprognostic (1.08e-2)" "unprognostic (4.62e-2)" "unprognostic (4.04e-2)" "unprognostic (2.79e-1)" "unprognostic (5.09e-2)" "unprognostic (6.67e-2)" "unprognostic (7.26e-3)" PDC MEKA ENSG00000116703 Phosducin P20941 1 186443566-186461114 "Predicted intracellular proteins" "Sensory transduction, Vision" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1642 "retina: 618.7" "Group enriched" "Detected in many" 22 "Cone photoreceptor cells: 621.0;Rod photoreceptor cells: 903.8" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Uterine cancer: 7.4" "Region enriched" "Detected in single" 5 "hippocampal formation: 3.0" "Low region specificity" "Detected in all" HPA062235 Enhanced NA NA "Cluster 42: Retina - Visual perception" "Cluster 34: Non-specific - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 79: Photoreceptor cells - Phototransduction" 2 "HPA062235: " PDCD1 "CD279, hSLE1, PD-1, PD1, SLEB2" ENSG00000188389 "Programmed cell death 1" Q15116 2 241849884-241858894 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Adaptive immunity, Apoptosis, Immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 6.4;lymphoid tissue: 15.0" "Cell type enriched" "Detected in single" 8 "T-cells: 2.0" "Cell type enriched" "Detected in single" 35 "leukocyte: 25.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "midbrain: 3.1" "Group enriched" "Detected in many" 5 "gdT-cell: 4.4;MAIT T-cell: 4.8;memory CD4 T-cell: 8.7;memory CD8 T-cell: 12.4;T-reg: 4.3" "Lineage enriched" "Detected in single" 55 "T-cells: 12.4" "Cancer enhanced" "Detected in some" "breast cancer: 1.2;lymphoma: 1.6" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Colon - T-cells, Prostate - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035981, CAB038418, CAB076386" Enhanced NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 19: Astrocytes - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 102: Non-specific - Mixed function" 11 "CAB038418: , CAB076386: , HPA035981: " "unprognostic (4.27e-2)" "unprognostic (1.50e-2)" "unprognostic (6.30e-3)" "unprognostic (2.35e-3)" "unprognostic (2.57e-2)" "unprognostic (1.79e-1)" "potential prognostic favorable (4.39e-4)" "unprognostic (1.92e-1)" "unprognostic (6.09e-2)" "unprognostic (1.88e-3)" "unprognostic (3.45e-1)" "unprognostic (7.17e-3)" "unprognostic (3.98e-1)" "unprognostic (1.65e-1)" "unprognostic (5.85e-2)" "unprognostic (9.20e-2)" "unprognostic (4.57e-3)" "unprognostic (6.28e-3)" "unprognostic (3.04e-1)" "unprognostic (1.64e-1)" "unprognostic (9.13e-2)" PDCD10 "CCM3, TFAR15" ENSG00000114209 "Programmed cell death 10" Q9BUL8 3 167683298-167734939 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Angiogenesis, Apoptosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 489.9;Megakaryocytes: 414.2;Platelets: 661.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027095 Approved NA NA 300000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 47: Platelets - Hemostasis" 49 "HPA027095: " "unprognostic (3.38e-1)" "unprognostic (1.01e-2)" "unprognostic (3.43e-2)" "unprognostic (1.55e-1)" "unprognostic (1.26e-1)" "unprognostic (1.30e-1)" "unprognostic (5.75e-2)" "unprognostic (5.05e-3)" "unprognostic (6.33e-3)" "potential prognostic unfavorable (7.96e-5)" "potential prognostic favorable (1.20e-5)" "unprognostic (1.13e-1)" "unprognostic (1.19e-1)" "potential prognostic unfavorable (4.54e-4)" "unprognostic (3.74e-3)" "unprognostic (4.92e-3)" "unprognostic (1.08e-2)" "unprognostic (2.64e-2)" "unprognostic (3.70e-2)" "unprognostic (2.03e-1)" "potential prognostic unfavorable (1.14e-6)" "validated prognostic unfavorable (8.99e-4)" "validated prognostic unfavorable (6.09e-6)" "unprognostic (2.42e-2)" "unprognostic (6.32e-2)" "unprognostic (4.26e-2)" "unprognostic (7.82e-3)" "unprognostic (2.08e-1)" "unprognostic (1.72e-1)" "unprognostic (1.52e-1)" "unprognostic (1.25e-1)" PDCD11 "ALG-4, KIAA0185, NFBP, RRP5" ENSG00000148843 "Programmed cell death 11" Q14690 10 103396626-103446294 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "rRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017924, CAB026472" Approved Supported "Nucleoli rim,Vesicles" NA NA 17000 "Cluster 33: Non-specific - ATP binding" "Cluster 39: Testis - Nuclear processes" "Cluster 6: Non-specific - Immune response" "Cluster 52: Non-specific - Mitochondria" "Cluster 17: Non-specific - RNA processing" 59 "Nucleoli rim" Vesicles "CAB026472: , HPA017924: " "unprognostic (1.62e-2)" "unprognostic (3.03e-1)" "unprognostic (2.02e-2)" "unprognostic (3.19e-3)" "unprognostic (5.87e-2)" "unprognostic (1.75e-1)" "unprognostic (1.60e-1)" "potential prognostic favorable (1.09e-5)" "unprognostic (1.09e-1)" "potential prognostic unfavorable (8.93e-4)" "unprognostic (1.31e-3)" "unprognostic (8.74e-2)" "unprognostic (1.32e-1)" "potential prognostic unfavorable (3.06e-4)" "unprognostic (1.62e-3)" "unprognostic (3.53e-2)" "potential prognostic unfavorable (9.57e-4)" "unprognostic (5.26e-2)" "unprognostic (2.66e-2)" "unprognostic (7.59e-2)" "unprognostic (2.10e-1)" "unprognostic (3.02e-3)" "unprognostic (1.18e-2)" "unprognostic (2.50e-2)" "unprognostic (1.98e-2)" "unprognostic (5.86e-3)" "unprognostic (1.78e-1)" "unprognostic (4.83e-2)" "unprognostic (1.37e-1)" "unprognostic (1.15e-2)" "unprognostic (3.20e-1)" PDCD1LG2 "B7-DC, bA574F11.2, Btdc, CD273, PD-L2, PDL2" ENSG00000197646 "Programmed cell death 1 ligand 2" Q9BQ51 9 5510531-5571282 "Cancer-related genes, CD markers, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 14.3" "Cell type enhanced" "Detected in many" "Adipocytes: 46.3;cDC: 21.1;Epicardial cells: 18.2;Extravillous trophoblasts: 54.8;Fibro-adipogenic progenitors: 30.6;Mast cells: 41.9;Microglia: 30.6" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 36.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Breast - Fibroblasts, Kidney - Endothelial cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA013411 Approved Uncertain Cytosol "Secreted - unknown location" Receptor NA NA 2000000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 30: White matter - Myelination" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 89: Adipocytes - Lipid metabolism" 21 Cytosol "HPA013411: " "unprognostic (1.99e-1)" "unprognostic (9.52e-2)" "unprognostic (3.44e-1)" "unprognostic (2.05e-1)" "unprognostic (1.65e-1)" "unprognostic (1.72e-1)" "unprognostic (1.96e-1)" "unprognostic (8.40e-2)" "unprognostic (8.52e-2)" "potential prognostic favorable (3.72e-4)" "unprognostic (1.11e-1)" "unprognostic (1.48e-3)" "unprognostic (1.68e-1)" "unprognostic (8.98e-2)" "unprognostic (9.24e-2)" "unprognostic (2.37e-1)" "unprognostic (2.11e-2)" "unprognostic (6.39e-2)" "unprognostic (1.22e-1)" "unprognostic (1.61e-1)" "unprognostic (8.62e-2)" "unprognostic (1.96e-2)" "unprognostic (1.52e-1)" "unprognostic (7.38e-2)" "unprognostic (2.73e-2)" "unprognostic (1.37e-1)" PDCD2 "RP8, ZMYND7" ENSG00000071994 "Programmed cell death 2" Q16342 6 170575295-170584692 "Essential proteins, Predicted intracellular proteins" Apoptosis DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026713, HPA075534" Approved Approved "Nucleoplasm,Cytokinetic bridge" Yes No "Cluster 3: Non-specific - Nuclear processes" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 21 Nucleoplasm "Cytokinetic bridge" "HPA026713: , HPA075534: " "unprognostic (4.14e-3)" "potential prognostic unfavorable (4.07e-5)" "unprognostic (1.45e-1)" "unprognostic (1.34e-2)" "unprognostic (1.33e-1)" "unprognostic (1.37e-2)" "unprognostic (1.04e-1)" "unprognostic (1.19e-2)" "unprognostic (3.94e-2)" "potential prognostic unfavorable (9.09e-4)" "potential prognostic favorable (1.80e-4)" "unprognostic (1.20e-1)" "unprognostic (3.82e-2)" "validated prognostic unfavorable (2.08e-9)" "validated prognostic unfavorable (1.49e-5)" "unprognostic (2.04e-2)" "unprognostic (1.44e-1)" "unprognostic (7.13e-2)" "unprognostic (3.80e-2)" "unprognostic (2.83e-3)" "unprognostic (5.33e-2)" "unprognostic (4.84e-1)" "unprognostic (6.06e-2)" "unprognostic (1.87e-1)" "unprognostic (2.45e-2)" "unprognostic (1.16e-1)" "unprognostic (1.23e-1)" "unprognostic (1.42e-1)" "unprognostic (2.37e-1)" "unprognostic (1.86e-1)" "unprognostic (2.36e-1)" PDCD2L MGC13096 ENSG00000126249 "Programmed cell death 2 like" Q9BRP1 19 34404399-34426168 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 24.2" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 54.0;Early primary spermatocytes: 33.3;Gastric progenitor cells: 46.1;Late primary spermatocytes: 58.0;Oocytes: 156.6;Undifferentiated spermatogonia: 29.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052181 Approved Approved Mitochondria NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 41: Oocytes - Oogenesis" 11 Mitochondria "HPA052181: " "unprognostic (1.55e-2)" "unprognostic (1.38e-1)" "unprognostic (4.27e-2)" "unprognostic (6.93e-3)" "unprognostic (2.07e-1)" "unprognostic (2.13e-1)" "unprognostic (1.62e-1)" "unprognostic (2.12e-3)" "unprognostic (1.15e-2)" "unprognostic (5.29e-2)" "unprognostic (1.33e-2)" "unprognostic (7.81e-2)" "unprognostic (8.52e-2)" "unprognostic (3.78e-3)" "unprognostic (1.67e-3)" "unprognostic (1.13e-3)" "unprognostic (3.51e-2)" "unprognostic (4.87e-2)" "unprognostic (1.09e-1)" "unprognostic (4.51e-1)" "unprognostic (7.00e-2)" "unprognostic (5.21e-2)" "unprognostic (2.33e-1)" "unprognostic (3.19e-2)" "unprognostic (5.47e-2)" "unprognostic (3.62e-2)" "unprognostic (5.14e-2)" "unprognostic (1.69e-1)" "unprognostic (1.71e-1)" "unprognostic (8.57e-2)" "unprognostic (9.61e-2)" PDCD4 H731 ENSG00000150593 "Programmed cell death 4" Q53EL6 10 110871795-110900006 "Predicted intracellular proteins" Apoptosis RNA-binding "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 476.5" "Cell type enhanced" "Detected in many" "Lacrimal acinar cells: 770.0;Pancreatic acinar cells: 764.2;Pituicytes/FSCs: 1128.2;Salivary acinar cells: 875.8;Syncytiotrophoblasts: 1127.9" "Cell type enhanced" "Detected in all" "endothelial cell: 357.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pituitary gland - Undifferentiated cells (Pituitary gland), Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001032, HPA027214, CAB037024" Enhanced Approved Nucleoplasm NA NA 4600 "Cluster 32: Basophils - Transcription" "Cluster 60: Stomach - Digestion" "Cluster 55: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 65 Nucleoplasm "CAB037024: , HPA001032: , HPA027214: " "unprognostic (3.66e-1)" "unprognostic (4.72e-2)" "unprognostic (1.88e-2)" "unprognostic (2.93e-1)" "unprognostic (2.90e-1)" "unprognostic (1.48e-1)" "unprognostic (3.87e-1)" "unprognostic (4.20e-3)" "unprognostic (1.87e-1)" "unprognostic (3.34e-1)" "potential prognostic favorable (5.47e-9)" "unprognostic (3.75e-3)" "unprognostic (3.92e-2)" "unprognostic (6.41e-2)" "unprognostic (7.53e-2)" "unprognostic (3.59e-2)" "unprognostic (1.55e-2)" "unprognostic (2.53e-1)" "unprognostic (1.77e-1)" "unprognostic (7.82e-2)" "unprognostic (4.01e-2)" "unprognostic (3.25e-1)" "unprognostic (1.08e-1)" "unprognostic (4.83e-2)" "unprognostic (1.82e-3)" "unprognostic (1.75e-2)" "unprognostic (5.60e-2)" "unprognostic (1.17e-1)" "unprognostic (2.04e-1)" "unprognostic (4.52e-2)" "unprognostic (6.27e-2)" PDCD5 "MGC9294, TFAR19" ENSG00000105185 "Programmed cell death 5" O14737 19 32581190-32587453 "Essential proteins, Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 8 "Oocytes: 5788.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018471 Enhanced Approved Nucleoplasm,Cytosol NA NA 140000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 24: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 4: Non-specific - Transcription" "Cluster 41: Oocytes - Oogenesis" 25 Cytosol Nucleoplasm "HPA018471: " "unprognostic (1.03e-1)" "unprognostic (1.64e-1)" "unprognostic (1.48e-1)" "unprognostic (5.50e-2)" "unprognostic (1.10e-1)" "unprognostic (3.05e-2)" "unprognostic (4.47e-3)" "unprognostic (3.14e-1)" "unprognostic (3.17e-3)" "unprognostic (5.36e-2)" "validated prognostic unfavorable (3.17e-10)" "validated prognostic unfavorable (1.23e-5)" "potential prognostic unfavorable (3.13e-8)" "validated prognostic unfavorable (2.76e-6)" "validated prognostic unfavorable (3.03e-5)" "potential prognostic unfavorable (1.46e-4)" "unprognostic (2.48e-2)" "unprognostic (4.41e-2)" "unprognostic (5.70e-2)" "unprognostic (3.96e-1)" "unprognostic (3.30e-2)" "unprognostic (6.79e-3)" "unprognostic (1.28e-2)" "unprognostic (2.12e-3)" "unprognostic (7.99e-2)" "unprognostic (2.15e-1)" "unprognostic (7.17e-2)" "unprognostic (8.49e-2)" "unprognostic (5.98e-2)" "unprognostic (3.11e-1)" "unprognostic (4.54e-2)" PDCD6 "ALG-2, PEF1B" ENSG00000249915 "Programmed cell death 6" O75340 5 271621-314974 "Plasma proteins, Predicted intracellular proteins, Transporters" "Angiogenesis, Apoptosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 36.4;Bergmann glia: 41.5;Brain excitatory neurons: 57.0;Brain inhibitory neurons: 47.2;Choroid plexus epithelial cells: 57.1;Distal convoluted tubule cells: 50.7;Ependymal cells: 44.7;Loop of henle epithelial cells: 46.5;Microglia: 53.4;Oligodendrocyte progenitor cells: 36.8;Oligodendrocytes: 60.8;Other brain neurons: 57.6;Papillary tip epithelial cells: 28.8;Podocytes: 56.3;Proximal tubule cells: 45.6;Renal collecting duct intercalated cells: 51.9;Renal collecting duct principal cells: 39.3;Renal connecting tubule cells: 48.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047221 Supported Nucleoplasm,Cytosol No No 1400000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 29: Non-specific - Unknown function" "Cluster 102: Non-specific - Mixed function" 50 Cytosol Nucleoplasm "HPA047221: " "unprognostic (9.50e-2)" "unprognostic (4.47e-3)" "unprognostic (5.22e-3)" "unprognostic (3.25e-1)" "unprognostic (1.16e-1)" "unprognostic (9.17e-2)" "unprognostic (4.05e-3)" "unprognostic (1.34e-2)" "unprognostic (1.61e-1)" "unprognostic (4.94e-3)" "unprognostic (7.50e-3)" "unprognostic (2.56e-2)" "unprognostic (5.18e-2)" "potential prognostic unfavorable (5.78e-6)" "unprognostic (2.15e-3)" "unprognostic (6.29e-2)" "unprognostic (8.85e-2)" "unprognostic (3.37e-2)" "unprognostic (1.16e-1)" "unprognostic (1.56e-1)" "unprognostic (1.09e-1)" "unprognostic (2.71e-1)" "unprognostic (1.20e-1)" "unprognostic (5.24e-2)" "unprognostic (1.68e-1)" "unprognostic (8.18e-2)" "unprognostic (1.71e-1)" "unprognostic (2.00e-1)" "unprognostic (1.53e-1)" "unprognostic (1.27e-1)" "unprognostic (5.95e-2)" PDCD6IP "AIP1, Alix, Hp95" ENSG00000170248 "Programmed cell death 6 interacting protein" Q8WUM4 3 33798571-33869707 "Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Host-virus interaction, Protein transport, Transport" "Intellectual disability, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 620.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "HPA011905, CAB016212, HPA051110, HPA051604" Supported Approved Vesicles,Centrosome "Intracellular and membrane" Transport NA NA 2300000 "Cluster 40: Monocytes - Innate immune response" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 78 Vesicles Centrosome "CAB016212: , HPA011905: , HPA051110: , HPA051604: " "unprognostic (1.53e-1)" "unprognostic (1.21e-1)" "unprognostic (3.95e-1)" "unprognostic (7.60e-2)" "unprognostic (9.31e-2)" "unprognostic (5.04e-1)" "unprognostic (3.45e-1)" "unprognostic (2.65e-1)" "unprognostic (8.48e-2)" "unprognostic (4.44e-3)" "potential prognostic favorable (2.88e-6)" "unprognostic (2.87e-3)" "unprognostic (2.69e-2)" "unprognostic (5.43e-3)" "unprognostic (7.52e-2)" "unprognostic (3.48e-2)" "unprognostic (8.60e-2)" "unprognostic (8.05e-2)" "unprognostic (2.03e-1)" "unprognostic (1.09e-1)" "unprognostic (1.68e-2)" "unprognostic (4.35e-3)" "unprognostic (1.67e-2)" "unprognostic (9.16e-2)" "unprognostic (9.27e-3)" "unprognostic (3.08e-1)" "unprognostic (2.71e-1)" "unprognostic (2.95e-1)" "unprognostic (3.29e-1)" "unprognostic (6.78e-2)" "unprognostic (1.05e-1)" PDCD7 "59K, ES18, HES18" ENSG00000090470 "Programmed cell death 7" Q8N8D1 15 65117379-65133808 "Essential proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 190.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049388 Approved Approved "Nucleoli,Plasma membrane" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 65: Brain - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 6 "Plasma membrane" Nucleoli "HPA049388: " "unprognostic (1.18e-2)" "unprognostic (4.16e-2)" "unprognostic (1.30e-1)" "unprognostic (9.91e-2)" "unprognostic (8.10e-2)" "unprognostic (4.04e-1)" "unprognostic (1.55e-1)" "unprognostic (6.62e-3)" "unprognostic (7.81e-2)" "unprognostic (8.46e-3)" "unprognostic (3.27e-2)" "unprognostic (1.58e-3)" "unprognostic (6.22e-3)" "unprognostic (1.43e-2)" "unprognostic (4.00e-2)" "unprognostic (3.33e-1)" "unprognostic (1.01e-3)" "unprognostic (3.87e-1)" "unprognostic (2.99e-2)" "unprognostic (1.88e-1)" "unprognostic (3.32e-1)" "unprognostic (8.94e-2)" "unprognostic (9.27e-3)" "unprognostic (2.26e-1)" "unprognostic (1.64e-2)" "unprognostic (3.21e-2)" "unprognostic (4.95e-2)" "unprognostic (6.85e-2)" "unprognostic (5.87e-2)" "unprognostic (6.12e-2)" "unprognostic (3.69e-1)" PDCL "DKFZp564M1863, PhLP" ENSG00000136940 "Phosducin like" Q13371 9 122798389-122828588 "Predicted intracellular proteins" "Cilium biogenesis/degradation, Sensory transduction, Vision" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021571, HPA021647, CAB026473" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 57 Cytosol Nucleoplasm "CAB026473: , HPA021571: , HPA021647: " "unprognostic (1.39e-1)" "unprognostic (3.56e-3)" "unprognostic (2.20e-1)" "unprognostic (3.80e-1)" "unprognostic (4.27e-2)" "unprognostic (1.63e-3)" "unprognostic (2.17e-1)" "unprognostic (3.16e-2)" "unprognostic (4.04e-1)" "unprognostic (3.32e-1)" "validated prognostic favorable (2.96e-8)" "validated prognostic favorable (2.10e-4)" "unprognostic (2.76e-1)" "unprognostic (8.58e-3)" "unprognostic (5.36e-2)" "unprognostic (6.57e-2)" "unprognostic (1.05e-1)" "unprognostic (2.55e-2)" "unprognostic (4.09e-2)" "unprognostic (1.60e-2)" "unprognostic (2.00e-2)" "unprognostic (2.39e-1)" "unprognostic (3.88e-1)" "unprognostic (1.75e-1)" "unprognostic (3.18e-2)" "unprognostic (1.27e-1)" "unprognostic (2.06e-2)" "unprognostic (7.23e-2)" "unprognostic (1.62e-1)" "unprognostic (1.62e-1)" "unprognostic (9.05e-2)" PDCL2 GCPHLP ENSG00000163440 "Phosducin like 2" Q8N4E4 4 55556519-55592245 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 206 "testis: 61.8" "Group enriched" "Detected in some" 17 "Early spermatids: 1630.0;Late primary spermatocytes: 529.8;Late spermatids: 904.2" "Cell type enhanced" "Detected in some" "MGE interneuron: 8.6;thalamic excitatory: 5.4" "Cancer enhanced" "Detected in some" "Ovary Serous Cystadenocarcinoma (TCGA): 2.5;Testicular Germ Cell Tumor (TCGA): 4.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pituitary gland - Lactotropes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA048260, HPA072384" Enhanced Approved Microtubules,Centrosome NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 24: Non-specific - Unknown function" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 1 Microtubules Centrosome "HPA048260: , HPA072384: " "unprognostic (1.89e-1)" "unprognostic (5.24e-3)" "unprognostic (3.77e-2)" "unprognostic (1.40e-1)" "potential prognostic unfavorable (7.93e-5)" PDCL3 VIAF1 ENSG00000115539 "Phosducin like 3" Q9H2J4 2 100562993-100576739 "Essential proteins, Predicted intracellular proteins" "Angiogenesis, Apoptosis" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 142.8;Undifferentiated spermatogonia: 84.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018469, HPA027094" Approved Enhanced Nucleoplasm,Cytosol No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 9: T-cells - Adaptive immunity: Regulation" 81 Cytosol Nucleoplasm "HPA018469: , HPA027094: " "unprognostic (6.11e-2)" "unprognostic (2.26e-2)" "unprognostic (1.14e-1)" "unprognostic (2.48e-3)" "unprognostic (3.66e-3)" "unprognostic (2.06e-1)" "unprognostic (7.49e-2)" "potential prognostic unfavorable (7.40e-4)" "unprognostic (1.68e-2)" "unprognostic (4.12e-2)" "unprognostic (4.34e-2)" "unprognostic (2.39e-1)" "unprognostic (3.50e-2)" "validated prognostic unfavorable (1.92e-4)" "validated prognostic unfavorable (1.95e-5)" "unprognostic (8.84e-3)" "unprognostic (2.26e-2)" "unprognostic (5.65e-2)" "unprognostic (5.85e-2)" "unprognostic (1.32e-1)" "unprognostic (1.35e-1)" "unprognostic (2.18e-1)" "unprognostic (1.98e-1)" "unprognostic (2.49e-1)" "unprognostic (1.70e-1)" "unprognostic (3.15e-1)" "unprognostic (2.81e-1)" "unprognostic (2.35e-2)" "unprognostic (1.39e-1)" "unprognostic (2.48e-1)" "unprognostic (1.29e-1)" PDE10A ENSG00000112541 "Phosphodiesterase 10A" Q9Y233 6 165327287-165988117 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Allosteric enzyme, Hydrolase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 719.9;Brain inhibitory neurons: 1309.7;Gonadotrophs: 1729.9;Lactotrophs: 2978.6;Müller glia: 1479.4;Somatotrophs: 2292.9;Urothelial cells: 1613.2" "Cell type enhanced" "Detected in all" "medium spiny neuron: 3075.4" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in all" 5 "basal ganglia: 147.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 21.3" "Liver - Vascular endothelial cells, Testis - Early spermatids" "Region enriched" "Detected in all" 11 "basal ganglia: 350.2" "Region enriched" "Detected in all" 4 "basal ganglia: 242.1" "CAB045998, HPA047200" Supported NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 33: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 1 "CAB045998: , HPA047200: " "unprognostic (2.02e-1)" "unprognostic (2.63e-3)" "unprognostic (4.53e-1)" "unprognostic (3.92e-2)" "potential prognostic favorable (4.14e-4)" "unprognostic (5.39e-2)" "unprognostic (3.47e-2)" "unprognostic (2.59e-1)" "unprognostic (1.28e-1)" "unprognostic (3.95e-1)" "unprognostic (2.32e-2)" "unprognostic (2.65e-2)" "unprognostic (3.57e-3)" "unprognostic (2.21e-2)" PDE11A ENSG00000128655 "Phosphodiesterase 11A" Q9HCR9 2 177623244-178108339 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Allosteric enzyme, Hydrolase" "Cushing syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 5.9;parathyroid gland: 9.7" "Cell type enriched" "Detected in many" 5 "Prostatic glandular cells: 1932.2" "Cell type enhanced" "Detected in some" "oligodendrocyte: 5.3;splatter: 4.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Kidney cancer: 6.5;Rhabdoid: 7.5" "Pancreas - Ductal cells, Pituitary gland - Lactotropes, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA034560, HPA034561" Approved Approved "Nucleoplasm,Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Centriolar satellite,Basal body,Cytosol" Yes NA "Cluster 76: Non-specific - Metabolism" "Cluster 30: White matter - Myelination" "Cluster 15: Kidney cancer - Membrane components" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" "Microtubules, Primary cilium" "Nucleoplasm, Cytokinetic bridge, Mitotic spindle, Centriolar satellite, Basal body, Cytosol" "HPA034560: , HPA034561: " "unprognostic (3.51e-1)" "unprognostic (1.73e-1)" "unprognostic (4.54e-3)" "unprognostic (4.52e-2)" "unprognostic (2.11e-2)" "unprognostic (6.57e-2)" "unprognostic (8.66e-2)" "unprognostic (2.74e-1)" "unprognostic (5.43e-2)" "unprognostic (3.99e-2)" "unprognostic (9.95e-2)" "unprognostic (2.55e-1)" PDE12 "2'-PDE, 3635, DKFZp667B1218" ENSG00000174840 "Phosphodiesterase 12" Q6L8Q7 3 57556274-57566848 "Enzymes, Predicted intracellular proteins" "mRNA processing" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043171 Approved NA NA 8300 "Cluster 5: Non-specific - Cell proliferation" "Cluster 76: Non-specific - Metabolism" "Cluster 55: Non-specific - Transcription" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 17: Non-specific - RNA processing" 6 "HPA043171: " "unprognostic (3.20e-2)" "unprognostic (9.03e-2)" "unprognostic (6.43e-2)" "unprognostic (6.70e-3)" "unprognostic (3.00e-3)" "unprognostic (2.00e-1)" "unprognostic (1.40e-1)" "unprognostic (6.55e-2)" "unprognostic (4.67e-2)" "unprognostic (2.63e-2)" "potential prognostic favorable (5.39e-7)" "unprognostic (1.90e-2)" "unprognostic (3.14e-2)" "unprognostic (7.55e-2)" "unprognostic (1.74e-2)" "unprognostic (9.62e-2)" "unprognostic (1.15e-3)" "unprognostic (3.00e-1)" "unprognostic (6.63e-2)" "unprognostic (1.92e-1)" "unprognostic (2.41e-2)" "unprognostic (1.14e-1)" "unprognostic (1.35e-1)" "unprognostic (4.51e-2)" "unprognostic (9.78e-2)" "unprognostic (5.91e-3)" "unprognostic (6.64e-3)" "unprognostic (1.19e-1)" "unprognostic (2.80e-1)" "unprognostic (3.71e-2)" "unprognostic (3.20e-1)" PDE1A ENSG00000115252 "Phosphodiesterase 1A" P54750 2 182139968-182523359 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 40.1" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 1085.0;Early spermatids: 389.9;Fibro-adipogenic progenitors: 328.4;Late spermatids: 1004.7;Loop of henle epithelial cells: 1112.0;Lymphatic endothelial cells: 466.0;Oligodendrocytes: 1141.7;Renal collecting duct intercalated cells: 1001.6;Renal collecting duct principal cells: 940.2;Renal connecting tubule cells: 409.1" "Cell type enhanced" "Detected in all" "deep-layer corticothalamic and 6b: 2463.4" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 39.1;Thyroid Carcinoma (TCGA): 45.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 4.5;thyroid cancer: 5.4" "Adrenal gland - Fibroblasts, Breast - Endothelial cells, Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022151 Approved Approved Nucleoplasm NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 34: Non-specific - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 2: Cerebellar granular cells - Neuronal signaling" Nucleoplasm "HPA022151: " "unprognostic (3.16e-1)" "unprognostic (3.42e-1)" "unprognostic (1.62e-1)" "unprognostic (4.55e-2)" "unprognostic (1.60e-1)" "unprognostic (4.52e-1)" "unprognostic (3.72e-3)" "unprognostic (9.08e-2)" "unprognostic (2.67e-2)" "unprognostic (1.94e-2)" "potential prognostic unfavorable (2.12e-4)" "unprognostic (2.48e-1)" "unprognostic (3.06e-2)" "unprognostic (2.55e-2)" "unprognostic (2.14e-1)" "unprognostic (1.03e-3)" "unprognostic (1.22e-3)" "unprognostic (5.56e-3)" "unprognostic (3.32e-2)" "unprognostic (2.58e-1)" "unprognostic (5.55e-2)" "unprognostic (1.92e-1)" "unprognostic (1.74e-2)" "unprognostic (3.37e-2)" "unprognostic (4.16e-3)" "unprognostic (7.18e-2)" "unprognostic (3.50e-1)" "unprognostic (5.00e-2)" PDE1B PDES1B ENSG00000123360 "Phosphodiesterase 1B" Q01064 12 54549601-54579239 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 95.6" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 18.4;Brain inhibitory neurons: 102.4;Hofbauer cells: 23.7;Kupffer cells: 33.8;Microglia: 17.3;monocytes: 18.4;Neutrophil progenitors: 20.1;Neutrophils: 32.4;Ovarian stromal cells: 18.1;Pericytes: 24.2;Retinal horizontal cells: 20.0;Smooth muscle cells: 23.4;Vascular smooth muscle cells: 24.4" "Cell type enhanced" "Detected in many" "medium spiny neuron: 260.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "basal ganglia: 192.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "Bone cancer: 8.0;Leukemia: 8.6;lymphoma: 5.7;Myeloma: 2.6" "Kidney - Endothelial cells, Pancreas - Endothelial cells, Prostate - Smooth muscle cells, Skeletal muscle - Endothelial cells" "Region enriched" "Detected in all" 6 "basal ganglia: 999.7" "Region enriched" "Detected in all" 7 "basal ganglia: 291.5" HPA018492 Enhanced NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" 1 "HPA018492: " "unprognostic (1.75e-1)" "unprognostic (3.46e-1)" "unprognostic (2.67e-3)" "unprognostic (6.02e-3)" "unprognostic (2.99e-3)" "potential prognostic favorable (5.40e-5)" "unprognostic (1.65e-2)" "unprognostic (3.20e-2)" "unprognostic (3.85e-2)" "unprognostic (5.44e-2)" "unprognostic (1.09e-2)" "unprognostic (6.68e-2)" "unprognostic (1.61e-1)" "potential prognostic favorable (6.18e-4)" "unprognostic (4.13e-1)" "unprognostic (3.30e-3)" "unprognostic (3.36e-1)" "unprognostic (3.12e-2)" PDE1C Hcam3 ENSG00000154678 "Phosphodiesterase 1C" Q14123 7 31751179-32428131 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 54.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 1733.9;Oligodendrocytes: 1240.0;Other brain neurons: 413.5;Renal collecting duct intercalated cells: 1635.7;Respiratory ionocytes: 1851.7;Retinal bipolar cells: 687.4;Salivary ionocytes: 2228.9" "Cell type enhanced" "Detected in all" "oligodendrocyte: 1534.9" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 14.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 48.4" "Breast - Breast myoepithelial cells, Heart muscle - Cardiomyocytes, Kidney - Intercalated cells, Minor Salivary Gland - Minor salivary gland ductal cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Prostate - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021751 Approved Mitochondria,Cytosol NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" "Mitochondria, Cytosol" "HPA021751: " "unprognostic (2.36e-2)" "unprognostic (2.09e-1)" "unprognostic (1.86e-1)" "unprognostic (2.89e-1)" "unprognostic (1.05e-3)" "unprognostic (1.89e-2)" "validated prognostic favorable (9.36e-5)" "validated prognostic favorable (2.72e-4)" "unprognostic (1.10e-2)" "unprognostic (3.03e-2)" "unprognostic (2.18e-3)" "unprognostic (8.34e-2)" "unprognostic (1.47e-2)" "unprognostic (2.78e-1)" PDE2A ENSG00000186642 "Phosphodiesterase 2A" O00408 11 72576141-72674591 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 119.7;lymphoid tissue: 187.7" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 63.8;Brain excitatory neurons: 62.1;Brain inhibitory neurons: 74.1;Lymphatic endothelial cells: 120.1;Neutrophils: 114.1;Tuft cells: 103.8;Vascular endothelial cells: 98.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 2.8;T-cells: 7.3" "Group enriched" "Detected in many" 4 "cervical cancer: 33.0;Neuroblastoma: 23.3" "Adipose visceral - Endothelial cells, Adrenal gland - Adrenal cortex cells, Breast - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Spleen - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "amygdala: 111.0;basal ganglia: 193.0;cerebral cortex: 119.4;hippocampal formation: 123.9" "CAB009752, HPA031192" Enhanced Supported Cytosol NA NA "Cluster 27: T-cells - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 51: Neurons - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 5 Cytosol "CAB009752: , HPA031192: " "unprognostic (6.94e-2)" "unprognostic (2.34e-1)" "unprognostic (6.23e-2)" "unprognostic (1.61e-3)" "unprognostic (1.40e-1)" "unprognostic (9.51e-2)" "unprognostic (4.41e-1)" "potential prognostic favorable (1.40e-4)" "unprognostic (2.91e-1)" "unprognostic (2.08e-1)" "validated prognostic favorable (2.91e-8)" "validated prognostic favorable (9.40e-6)" "unprognostic (7.01e-3)" "validated prognostic favorable (8.83e-5)" "validated prognostic favorable (1.36e-7)" "unprognostic (8.24e-2)" "unprognostic (1.64e-2)" "unprognostic (1.66e-3)" "unprognostic (6.39e-3)" "potential prognostic unfavorable (4.89e-4)" "unprognostic (2.44e-1)" "unprognostic (2.18e-3)" "unprognostic (9.06e-2)" "unprognostic (2.24e-2)" "unprognostic (2.80e-1)" "unprognostic (1.00e-1)" "unprognostic (1.27e-1)" "potential prognostic unfavorable (6.43e-4)" "unprognostic (4.45e-2)" "unprognostic (4.62e-2)" "unprognostic (1.28e-1)" PDE3A CGI-PDE ENSG00000172572 "Phosphodiesterase 3A" Q14432 12 20368537-20688583 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" Hydrolase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 19.9;heart muscle: 28.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 4516.2;Enterocytes: 856.4;Pancreatic duct cells: 665.0;Pericytes: 705.6;Pituicytes/FSCs: 1070.1;Retinal amacrine cells: 730.9;Retinal bipolar cells: 581.8;Retinal horizontal cells: 1166.0;Vascular smooth muscle cells: 1060.7" "Cell type enriched" "Detected in all" 4 "vascular associated smooth muscle cell: 2523.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 7.4" "Adipose subcutaneous - Smooth muscle cells, Breast - Endothelial cells, Prostate - Smooth muscle cells, Skin - Endothelial cells" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 18.4" "HPA014492, HPA074258" Approved Approved "Plasma membrane" NA NA 24000 "Cluster 35: Non-specific - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 7 "Plasma membrane" "HPA014492: , HPA074258: " "unprognostic (6.53e-2)" "unprognostic (8.36e-2)" "unprognostic (7.11e-3)" "unprognostic (1.17e-1)" "unprognostic (1.28e-1)" "unprognostic (2.67e-1)" "unprognostic (1.18e-1)" "unprognostic (1.03e-3)" "potential prognostic favorable (4.05e-4)" "unprognostic (6.80e-2)" "unprognostic (3.94e-2)" "unprognostic (1.42e-2)" "unprognostic (2.96e-1)" "unprognostic (3.96e-1)" "unprognostic (2.73e-1)" "unprognostic (1.31e-1)" "unprognostic (2.90e-2)" "unprognostic (3.03e-1)" "unprognostic (5.24e-2)" "unprognostic (1.48e-1)" "unprognostic (1.01e-1)" "unprognostic (2.12e-2)" "unprognostic (1.64e-1)" "unprognostic (1.03e-1)" PDE3B HcGIP1 ENSG00000152270 "Phosphodiesterase 3B" Q13370 11 14643804-14872044 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins" Angiogenesis Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 60.6" "Cell type enhanced" "Detected in many" "Adipocytes: 2847.0;Microglia: 490.4;Neutrophils: 1416.8;Pancreatic islet cells: 463.1;Salivary acinar cells: 515.4;Somatotrophs: 446.7;T-cells: 827.1;Thyrotrophs: 539.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "granulocytes: 3.9;T-cells: 6.3" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056111 Approved "Endoplasmic reticulum" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 35: Non-specific - DNA binding" "Cluster 59: Leukemia - T-cell receptor" "Cluster 89: Adipocytes - Lipid metabolism" 18 "Endoplasmic reticulum" "HPA056111: " "unprognostic (2.99e-1)" "unprognostic (6.30e-2)" "unprognostic (9.07e-3)" "unprognostic (3.59e-2)" "unprognostic (1.70e-1)" "unprognostic (5.50e-2)" "unprognostic (2.20e-1)" "unprognostic (1.79e-3)" "unprognostic (1.18e-3)" "unprognostic (7.29e-3)" "unprognostic (1.33e-2)" "unprognostic (2.33e-1)" "potential prognostic unfavorable (5.12e-4)" "unprognostic (1.27e-2)" "unprognostic (2.72e-1)" "unprognostic (1.43e-2)" "unprognostic (1.91e-2)" "unprognostic (3.25e-2)" "unprognostic (2.51e-1)" "potential prognostic favorable (3.65e-4)" "unprognostic (7.50e-3)" "unprognostic (3.02e-1)" "unprognostic (4.62e-2)" "unprognostic (1.91e-1)" "unprognostic (1.36e-3)" "unprognostic (1.02e-2)" "unprognostic (1.18e-1)" "unprognostic (5.05e-2)" PDE4A DPDE2 ENSG00000065989 "Phosphodiesterase 4A" P27815 19 10416773-10469630 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "cDC: 306.8;Innate lymphoid cells: 297.4;Late spermatids: 399.1;Macrophages: 130.5;Mast cells: 256.9;monocytes: 205.8;NK-cells: 237.4;pDCs: 153.3;T-cells: 187.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017632, HPA043310, HPA076091" Uncertain Supported "Plasma membrane" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 47: Leukemia - Hemostasis" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" "Plasma membrane" "CAB017632: , HPA043310: , HPA076091: " "unprognostic (6.10e-3)" "unprognostic (1.21e-3)" "unprognostic (5.89e-2)" "unprognostic (1.37e-1)" "unprognostic (6.44e-2)" "unprognostic (1.88e-2)" "unprognostic (5.99e-2)" "unprognostic (5.61e-2)" "unprognostic (5.69e-2)" "unprognostic (8.71e-2)" "unprognostic (1.96e-3)" "unprognostic (2.05e-2)" "unprognostic (1.94e-1)" "unprognostic (1.44e-2)" "unprognostic (1.71e-2)" "unprognostic (2.72e-1)" "unprognostic (1.93e-2)" "unprognostic (3.51e-2)" "unprognostic (8.93e-2)" "potential prognostic unfavorable (8.66e-4)" "unprognostic (3.94e-2)" "unprognostic (8.68e-3)" "unprognostic (2.10e-1)" "unprognostic (2.12e-1)" "unprognostic (3.75e-2)" "unprognostic (1.63e-1)" "unprognostic (1.35e-2)" "unprognostic (7.77e-2)" "unprognostic (2.47e-2)" "unprognostic (1.27e-1)" "unprognostic (2.38e-1)" PDE4B DPDE4 ENSG00000184588 "Phosphodiesterase 4B" Q07343 1 65792514-66374579 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 71.3" "Cell type enhanced" "Detected in many" "Astrocytes: 983.5;Bergmann glia: 1175.3;monocytes: 1059.4;Neutrophils: 3699.4;Oligodendrocyte progenitor cells: 2472.8;Oligodendrocytes: 4839.5;pDCs: 1134.6;Plasma cells: 892.7;Retinal bipolar cells: 1183.4;Retinal horizontal cells: 1765.0" "Cell type enhanced" "Detected in all" "oligodendrocyte: 5976.5" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 64.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 89.5" "Group enriched" "Detected in all" 5 "B-cells: 37.6;granulocytes: 89.5;T-cells: 34.8" "Cancer enhanced" "Detected in many" "Rhabdoid: 47.5" "Colon - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003005 Uncertain Approved "Golgi apparatus,Primary cilium,Cytosol" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 8 "Golgi apparatus" "Primary cilium, Cytosol" "HPA003005: " "unprognostic (2.02e-1)" "unprognostic (1.57e-1)" "unprognostic (1.94e-2)" "unprognostic (1.53e-1)" "unprognostic (4.87e-2)" "unprognostic (7.90e-2)" "unprognostic (2.57e-1)" "unprognostic (1.01e-1)" "unprognostic (8.85e-3)" "unprognostic (5.31e-2)" "unprognostic (5.20e-2)" "unprognostic (6.07e-3)" "unprognostic (3.94e-1)" "unprognostic (1.40e-1)" "unprognostic (1.94e-1)" "potential prognostic favorable (5.48e-4)" "unprognostic (5.17e-2)" "unprognostic (1.68e-1)" "unprognostic (1.29e-1)" "unprognostic (2.70e-3)" "unprognostic (5.40e-1)" "unprognostic (6.51e-2)" "unprognostic (3.07e-1)" "unprognostic (3.98e-2)" "unprognostic (5.31e-1)" "unprognostic (8.69e-2)" "unprognostic (1.81e-2)" "unprognostic (7.48e-3)" "unprognostic (2.47e-1)" "unprognostic (6.15e-3)" "unprognostic (3.10e-1)" PDE4C DPDE1 ENSG00000105650 "Phosphodiesterase 4C" Q08493 19 18207965-18248200 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 10.8;tongue: 23.0" "Cell type enhanced" "Detected in some" "Astrocytes: 1.0;Bergmann glia: 1.2;Brain excitatory neurons: 6.1;Brain inhibitory neurons: 3.0;Ependymal cells: 1.3;Other brain neurons: 2.5;Pericytes: 4.4;Vascular smooth muscle cells: 4.9" "Group enriched" "Detected in many" 5 "pericyte: 107.6;vascular associated smooth muscle cell: 88.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 2.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA048975, HPA054218" Approved Approved "Midbody ring,Centrosome,Basal body,Cytosol" Yes NA "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 51: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 22: Non-specific - Basic cellular functions" "Centrosome, Basal body, Cytosol" "Midbody ring" "HPA048975: , HPA054218: " "unprognostic (7.28e-2)" "unprognostic (7.85e-2)" "unprognostic (2.52e-1)" "unprognostic (6.93e-3)" "unprognostic (5.55e-2)" "unprognostic (1.21e-3)" "unprognostic (5.57e-2)" "unprognostic (2.42e-2)" "unprognostic (7.16e-2)" "unprognostic (1.57e-1)" "unprognostic (1.36e-1)" "unprognostic (4.83e-2)" PDE4D DPDE3 ENSG00000113448 "Phosphodiesterase 4D" Q08499 5 58969038-60522120 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 70.7;skeletal muscle: 63.5" "Cell type enhanced" "Detected in all" "Myonuclei: 8670.8;Neutrophil progenitors: 5306.2;Prostatic glandular cells: 7016.6;Proximal tubule cells: 4114.6;Renal collecting duct intercalated cells: 4569.2;Renal collecting duct principal cells: 4333.3;Renal connecting tubule cells: 10730.8;Salivary acinar cells: 5022.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "eosinophil: 58.2" "Lineage enriched" "Detected in many" 5 "granulocytes: 58.2" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045895 Uncertain Approved "Nucleoplasm,Nuclear membrane,Plasma membrane,Primary cilium,Cytosol" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 7: Liver cancer - Metabolism" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 19 "Plasma membrane, Cytosol" "Nucleoplasm, Nuclear membrane, Primary cilium" "HPA045895: " "unprognostic (2.73e-2)" "unprognostic (1.77e-1)" "unprognostic (7.47e-2)" "potential prognostic unfavorable (4.94e-4)" "unprognostic (2.29e-2)" "unprognostic (5.48e-2)" "unprognostic (3.21e-2)" "unprognostic (1.51e-1)" "unprognostic (9.15e-2)" "potential prognostic unfavorable (4.19e-4)" "potential prognostic favorable (2.53e-8)" "unprognostic (2.01e-2)" "unprognostic (6.58e-2)" "unprognostic (2.29e-3)" "unprognostic (9.25e-2)" "unprognostic (1.01e-1)" "unprognostic (2.94e-2)" "unprognostic (1.38e-1)" "unprognostic (6.87e-2)" "unprognostic (1.27e-1)" "unprognostic (2.81e-1)" "unprognostic (6.46e-2)" "unprognostic (1.62e-1)" "unprognostic (1.11e-1)" "unprognostic (6.08e-2)" "unprognostic (2.54e-1)" "unprognostic (1.82e-1)" "unprognostic (1.42e-1)" "unprognostic (2.73e-2)" "unprognostic (1.21e-2)" "unprognostic (9.13e-2)" PDE4DIP "CMYA2, KIAA0454, KIAA0477, MMGL" ENSG00000178104 "Phosphodiesterase 4D interacting protein" Q5VU43 1 148808140-149048286 "Cancer-related genes, Disease related genes, Essential proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "heart muscle: 686.9;skeletal muscle: 1934.8;tongue: 1153.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 1132.7;Loop of henle epithelial cells: 305.2;Myonuclei: 1537.8;Podocytes: 1129.4;Thymic myoid cells: 594.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012678 Supported "Golgi apparatus" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 15: Non-specific - Transcription" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 55: Myocytes - Oxidative muscle function" 58 "Golgi apparatus" "HPA012678: " "unprognostic (7.68e-2)" "unprognostic (1.24e-1)" "unprognostic (1.91e-1)" "unprognostic (6.21e-2)" "unprognostic (3.83e-1)" "unprognostic (2.43e-2)" "unprognostic (1.23e-1)" "unprognostic (1.11e-1)" "unprognostic (1.65e-2)" "unprognostic (3.16e-2)" "unprognostic (1.73e-2)" "unprognostic (6.19e-2)" "unprognostic (1.52e-1)" "unprognostic (1.21e-1)" "unprognostic (7.28e-2)" "unprognostic (2.20e-1)" "unprognostic (1.22e-2)" "unprognostic (5.91e-2)" "unprognostic (4.56e-2)" "unprognostic (3.35e-2)" "unprognostic (3.18e-1)" "unprognostic (4.80e-2)" "unprognostic (1.38e-2)" "unprognostic (2.41e-1)" "unprognostic (6.87e-3)" "unprognostic (2.67e-1)" "unprognostic (8.49e-3)" "unprognostic (4.66e-2)" "unprognostic (6.81e-2)" "unprognostic (1.98e-1)" "unprognostic (1.26e-1)" PDE5A ENSG00000138735 "Phosphodiesterase 5A" O76074 4 119494397-119628804 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Allosteric enzyme, Hydrolase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 362.0;Cardiomyocytes: 588.8;Epicardial cells: 498.0;Fibro-adipogenic progenitors: 334.3;Myonuclei: 310.9;Peritubular myoid cells: 329.7;Platelets: 551.1;Vascular smooth muscle cells: 333.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Thyroid Carcinoma (TCGA): 61.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Testis - Peritubular cells, Thyroid gland - Fibroblasts" "Region enhanced" "Detected in all" "cerebellum: 18.2" "Low region specificity" "Detected in all" "HPA004729, HPA012873" Approved Approved "Basal body,Cytosol" NA NA 1200000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 110: Mural cells - ECM organization" 6 Cytosol "Basal body" "HPA004729: , HPA012873: " "unprognostic (5.31e-3)" "unprognostic (1.33e-1)" "potential prognostic unfavorable (3.93e-4)" "unprognostic (3.39e-2)" "unprognostic (7.13e-2)" "unprognostic (1.81e-1)" "unprognostic (1.52e-1)" "unprognostic (1.75e-1)" "unprognostic (7.17e-2)" "potential prognostic unfavorable (1.76e-4)" "unprognostic (2.55e-3)" "potential prognostic favorable (6.20e-4)" "unprognostic (2.93e-2)" "unprognostic (1.80e-2)" "unprognostic (1.66e-1)" "unprognostic (5.57e-2)" "unprognostic (1.99e-1)" "unprognostic (2.27e-1)" "unprognostic (1.40e-1)" "unprognostic (1.32e-1)" "unprognostic (2.64e-2)" "unprognostic (9.68e-2)" "unprognostic (6.40e-2)" "unprognostic (1.36e-1)" "unprognostic (3.73e-2)" "unprognostic (4.47e-3)" "unprognostic (3.42e-2)" "unprognostic (3.84e-2)" "unprognostic (1.97e-1)" "unprognostic (2.12e-2)" "unprognostic (9.70e-3)" PDE6A "PDEA, RP43" ENSG00000132915 "Phosphodiesterase 6A" P16499 5 149857953-149944793 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Sensory transduction, Vision" Hydrolase "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 65 "retina: 1001.0" "Cell type enriched" "Detected in many" 24 "Rod photoreceptor cells: 6364.0" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Sebaceous gland cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA016970, HPA074677" Enhanced NA NA "Cluster 42: Retina - Visual perception" "Cluster 48: Non-specific - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 79: Photoreceptor cells - Phototransduction" "HPA016970: , HPA074677: " "unprognostic (1.90e-3)" "unprognostic (1.35e-2)" "unprognostic (9.40e-3)" PDE6B "CSNB3, CSNBAD2, PDEB, rd1, RP40" ENSG00000133256 "Phosphodiesterase 6B" P35913 4 625573-670782 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Sensory transduction, Vision" Hydrolase "Congenital stationary night blindness, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "retina: 357.2" "Cell type enriched" "Detected in many" 5 "Rod photoreceptor cells: 628.1" "Cell type enhanced" "Detected in many" "oligodendrocyte: 86.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA054148, HPA059929" Enhanced Uncertain "Vesicles,Basal body,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 42: Retina - Visual perception" "Cluster 11: White matter - Signal transduction" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 79: Photoreceptor cells - Phototransduction" 1 "Basal body, Cytosol" Vesicles "HPA054148: , HPA059929: " "unprognostic (4.81e-3)" "unprognostic (1.06e-1)" "unprognostic (1.62e-1)" "potential prognostic favorable (1.32e-4)" "unprognostic (2.20e-1)" "unprognostic (1.53e-1)" "unprognostic (7.79e-3)" "potential prognostic unfavorable (1.09e-4)" "unprognostic (8.44e-3)" "unprognostic (3.25e-2)" "unprognostic (3.65e-3)" "unprognostic (1.12e-2)" "potential prognostic favorable (6.96e-4)" "potential prognostic unfavorable (3.03e-4)" "potential prognostic favorable (4.68e-4)" "unprognostic (3.75e-1)" "unprognostic (4.90e-2)" "unprognostic (1.61e-1)" "unprognostic (1.49e-1)" "unprognostic (1.10e-1)" "unprognostic (9.31e-3)" "unprognostic (1.83e-1)" "unprognostic (1.07e-1)" "unprognostic (1.99e-1)" "unprognostic (2.87e-2)" "unprognostic (1.73e-1)" "unprognostic (6.53e-2)" "unprognostic (1.08e-1)" "potential prognostic unfavorable (2.97e-4)" "unprognostic (1.46e-1)" PDE6C "ACHM5, COD4, PDEA2" ENSG00000095464 "Phosphodiesterase 6C" P51160 10 93612537-93666010 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Sensory transduction, Vision" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 35 "retina: 21.4" "Cell type enriched" "Detected in many" 13 "Cone photoreceptor cells: 262.9" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 42: Retina - Visual perception" "Cluster 9: Non-specific - Receptor signaling" "Cluster 1: Neuronal - Visual perception" "Cluster 79: Photoreceptor cells - Phototransduction" "unprognostic (1.04e-2)" PDE6D JBTS22 ENSG00000156973 "Phosphodiesterase 6D" O43924 2 231732433-231786272 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Ciliopathy, Joubert syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 224.0;Early spermatids: 173.9;Late primary spermatocytes: 417.2;Late spermatids: 218.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037433, HPA037434" Uncertain Supported Vesicles NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 48 Vesicles "HPA037433: , HPA037434: " "unprognostic (1.90e-1)" "unprognostic (7.92e-2)" "unprognostic (2.01e-1)" "unprognostic (1.13e-1)" "unprognostic (1.64e-1)" "unprognostic (3.80e-2)" "unprognostic (1.75e-1)" "unprognostic (4.66e-2)" "unprognostic (5.48e-2)" "unprognostic (1.47e-2)" "unprognostic (7.14e-2)" "unprognostic (1.08e-1)" "unprognostic (9.30e-2)" "potential prognostic unfavorable (1.20e-4)" "unprognostic (5.87e-3)" "unprognostic (3.12e-1)" "unprognostic (8.16e-2)" "unprognostic (8.42e-2)" "unprognostic (2.22e-1)" "unprognostic (4.53e-2)" "unprognostic (4.95e-2)" "unprognostic (1.90e-1)" "unprognostic (6.61e-2)" "unprognostic (1.58e-1)" "unprognostic (1.17e-2)" "unprognostic (2.84e-1)" "unprognostic (2.72e-1)" "unprognostic (4.15e-2)" "unprognostic (2.96e-1)" "unprognostic (2.93e-2)" "unprognostic (2.40e-2)" PDE6G "PDEG, RP57" ENSG00000185527 "Phosphodiesterase 6G" P18545 17 81650459-81663112 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" Hydrolase "Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 98 "retina: 1904.6" "Cell type enriched" "Detected in some" 30 "Rod photoreceptor cells: 3181.6" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 25.0" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 6 "basophil: 127.6;NK-cell: 220.8" "Group enriched" "Detected in all" 6 "granulocytes: 127.6;NK-cells: 220.8" "Group enriched" "Detected in some" 5 "Leukemia: 12.6;testis cancer: 5.7" "Minor Salivary Gland - Macrophages, Spleen - Macrophages" "Region enhanced" "Detected in some" "hippocampal formation: 4.7" "Low region specificity" "Detected in some" HPA045118 Supported Uncertain Vesicles NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 42: Retina - Visual perception" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 47: Leukemia - Hemostasis" "Cluster 79: Photoreceptor cells - Phototransduction" 5 Vesicles "HPA045118: " "unprognostic (1.12e-2)" "unprognostic (9.87e-2)" "unprognostic (7.47e-2)" "unprognostic (2.91e-2)" "unprognostic (3.43e-1)" "unprognostic (8.76e-2)" "unprognostic (2.66e-1)" "unprognostic (7.40e-2)" "unprognostic (1.40e-1)" "unprognostic (2.29e-1)" "unprognostic (5.06e-2)" "unprognostic (1.34e-1)" "unprognostic (5.46e-2)" "unprognostic (1.28e-1)" "unprognostic (1.72e-1)" "unprognostic (1.26e-1)" "unprognostic (1.92e-1)" "unprognostic (1.48e-1)" "unprognostic (4.40e-2)" "unprognostic (4.42e-2)" "potential prognostic favorable (2.68e-4)" "unprognostic (2.72e-2)" "unprognostic (9.79e-3)" "unprognostic (1.89e-1)" "unprognostic (6.51e-2)" PDE6H ENSG00000139053 "Phosphodiesterase 6H" Q13956 12 14973042-14981865 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 81 "retina: 844.1" "Cell type enriched" "Detected in some" 60 "Cone photoreceptor cells: 2260.6" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in many" "hypothalamus: 4.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Brain cancer: 2.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA045118 Supported Uncertain Vesicles NA NA "Cluster 42: Retina - Visual perception" "Cluster 23: Choroid plexus - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 79: Photoreceptor cells - Phototransduction" 5 Vesicles "HPA045118: " PDE7A HCP1 ENSG00000205268 "Phosphodiesterase 7A" Q13946 8 65714334-65842322 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 100.9;tongue: 70.9" "Cell type enhanced" "Detected in many" "B-cells: 700.8;Corticotrophs: 611.7;Myonuclei: 924.3;NK-cells: 555.4;Proximal tubule cells: 646.6;T-cells: 574.9;Thymocytes: 985.8" "Cell type enhanced" "Detected in all" "leukocyte: 830.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - T-cells, Heart muscle - Cardiomyocytes, Spleen - B-cells (Spleen), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018770, HPA027340" Approved NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 11: White matter - Signal transduction" "Cluster 59: Leukemia - T-cell receptor" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 6 "CAB018770: , HPA027340: " "unprognostic (7.31e-2)" "unprognostic (4.30e-1)" "unprognostic (1.60e-1)" "unprognostic (1.09e-1)" "unprognostic (1.80e-1)" "unprognostic (1.83e-1)" "unprognostic (1.26e-1)" "unprognostic (1.56e-3)" "unprognostic (1.87e-1)" "unprognostic (3.08e-1)" "unprognostic (1.51e-2)" "unprognostic (1.91e-2)" "unprognostic (3.82e-3)" "potential prognostic unfavorable (1.56e-4)" "unprognostic (4.19e-1)" "unprognostic (7.39e-2)" "unprognostic (2.19e-1)" "unprognostic (1.38e-1)" "unprognostic (3.71e-2)" "unprognostic (7.28e-2)" "unprognostic (1.25e-1)" "unprognostic (5.83e-2)" "unprognostic (1.11e-1)" "unprognostic (1.08e-1)" "unprognostic (5.49e-2)" "unprognostic (2.40e-2)" "unprognostic (8.72e-2)" "unprognostic (1.52e-1)" "unprognostic (2.53e-1)" "unprognostic (3.24e-1)" "unprognostic (1.15e-1)" PDE7B ENSG00000171408 "Phosphodiesterase 7B" Q9NP56 6 135851701-136195574 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 539.3;Distal convoluted tubule cells: 477.6;Mast cells: 457.9;Medullary thymic epithelial cells: 547.3;Myosatellite cells: 630.7;Oligodendrocyte progenitor cells: 510.8;Pituicytes/FSCs: 2708.0;Podocytes: 906.7;Renal collecting duct principal cells: 673.2" "Cell type enhanced" "Detected in all" "medium spiny neuron: 1106.8;pericyte: 2559.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.3" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 5.1" "Colon - Enteric glia cells" "Region enriched" "Detected in all" 5 "basal ganglia: 125.4" "Low region specificity" "Detected in all" HPA023967 Uncertain Approved Nucleoplasm No NA "Cluster 18: Non-specific - Translation" "Cluster 65: Brain - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 7: Liver cancer - Metabolism" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" Nucleoplasm "HPA023967: " "unprognostic (2.22e-2)" "unprognostic (1.94e-1)" "unprognostic (5.47e-2)" "unprognostic (1.36e-1)" "unprognostic (3.71e-1)" "unprognostic (2.13e-3)" "unprognostic (3.49e-1)" "validated prognostic favorable (7.76e-7)" "validated prognostic favorable (1.67e-4)" "potential prognostic favorable (2.48e-4)" "potential prognostic favorable (1.20e-4)" "unprognostic (3.40e-1)" "unprognostic (6.59e-2)" "unprognostic (2.42e-1)" "unprognostic (9.09e-3)" "unprognostic (1.91e-2)" "unprognostic (2.72e-2)" "unprognostic (4.58e-2)" "unprognostic (8.64e-2)" "unprognostic (5.59e-3)" "unprognostic (1.01e-1)" "unprognostic (2.12e-1)" "unprognostic (1.10e-1)" PDE8A HsT19550 ENSG00000073417 "Phosphodiesterase 8A" O60658 15 84980440-85139145 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 1223.4;Proximal tubule cells: 657.0" "Cell type enhanced" "Detected in all" "oligodendrocyte: 1541.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007722 Approved Approved "Golgi apparatus" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 76: Non-specific - Metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 7: Liver cancer - Metabolism" "Cluster 80: Oligodendrocytes - Myelination" 1 "Golgi apparatus" "HPA007722: " "unprognostic (1.98e-1)" "unprognostic (5.68e-2)" "unprognostic (1.00e-2)" "unprognostic (1.51e-2)" "unprognostic (1.07e-2)" "unprognostic (1.61e-1)" "unprognostic (2.91e-2)" "unprognostic (4.99e-3)" "unprognostic (1.46e-1)" "unprognostic (2.49e-1)" "validated prognostic favorable (8.01e-10)" "validated prognostic favorable (4.70e-4)" "unprognostic (8.63e-2)" "unprognostic (1.03e-1)" "unprognostic (2.02e-2)" "unprognostic (1.16e-1)" "unprognostic (1.80e-1)" "unprognostic (3.04e-1)" "unprognostic (5.96e-2)" "unprognostic (1.54e-1)" "unprognostic (3.15e-1)" "unprognostic (4.98e-2)" "unprognostic (9.64e-2)" "unprognostic (3.80e-2)" "unprognostic (1.20e-2)" "unprognostic (3.79e-1)" "unprognostic (3.24e-1)" "unprognostic (1.10e-1)" "unprognostic (4.48e-1)" "unprognostic (3.95e-2)" "potential prognostic unfavorable (4.87e-6)" PDE8B ENSG00000113231 "Phosphodiesterase 8B" O95263 5 77210449-77428256 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Cushing syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "thyroid gland: 116.7" "Cell type enhanced" "Detected in many" "Astrocytes: 85.0;Brain excitatory neurons: 146.5;Brain inhibitory neurons: 248.3;Ependymal cells: 68.4;Oligodendrocyte progenitor cells: 344.4;Oligodendrocytes: 64.5;Other brain neurons: 224.6;Pericytes: 93.7;Prostatic glandular cells: 82.4" "Cell type enhanced" "Detected in all" "pericyte: 1895.2" "Cancer enriched" "Detected in many" 6 "Thyroid Carcinoma (TCGA): 86.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Pituitary gland - Lactotropes, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036911, HPA036912" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 33: Thyroid gland - Tissue development" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 32: Non-specific - Cell proliferation" "Cluster 22: Non-specific - Basic cellular functions" "Nucleoplasm, Cytosol" "HPA036911: , HPA036912: " "unprognostic (5.31e-3)" "unprognostic (6.14e-2)" "unprognostic (3.64e-1)" "unprognostic (9.16e-2)" "unprognostic (2.57e-2)" "unprognostic (2.08e-2)" "unprognostic (1.72e-3)" "unprognostic (3.47e-2)" "unprognostic (4.97e-3)" "unprognostic (6.00e-3)" "unprognostic (5.91e-3)" "unprognostic (1.09e-1)" "unprognostic (2.48e-2)" "potential prognostic favorable (8.68e-4)" "unprognostic (1.08e-1)" "unprognostic (1.77e-1)" "unprognostic (3.26e-3)" "unprognostic (2.03e-1)" "unprognostic (3.78e-1)" "unprognostic (2.14e-1)" "unprognostic (1.12e-2)" "unprognostic (1.20e-1)" "unprognostic (8.43e-2)" "unprognostic (3.17e-1)" PDE9A ENSG00000160191 "Phosphodiesterase 9A" O76083 21 42653621-42775509 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 69.9" "Cell type enhanced" "Detected in many" "Enterocytes: 513.9;Loop of henle epithelial cells: 197.6;Oocytes: 216.4;Prostatic glandular cells: 323.4;Renal collecting duct principal cells: 165.5;Renal connecting tubule cells: 184.7;Retinal horizontal cells: 202.3;Somatotrophs: 191.4" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in all" 4 "Prostate Adenocarcinoma (TCGA): 97.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 3.1" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "prostate cancer: 40.8" "Adipose subcutaneous - Endothelial cells, Minor Salivary Gland - Minor salivary gland ductal cells, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011380, HPA011978" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 77: Intestine - Digestion" "Cluster 19: Astrocytes - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 1: Enterocytes - Absorption and Digestion" 17 Cytosol "Nucleoplasm, Plasma membrane" "HPA011380: , HPA011978: " "unprognostic (9.94e-2)" "unprognostic (2.11e-2)" "unprognostic (2.61e-1)" "unprognostic (1.92e-2)" "unprognostic (2.84e-2)" "unprognostic (1.10e-1)" "unprognostic (1.69e-1)" "unprognostic (1.43e-1)" "unprognostic (1.39e-1)" "unprognostic (3.17e-1)" "validated prognostic favorable (5.66e-7)" "validated prognostic favorable (8.31e-6)" "unprognostic (2.06e-2)" "unprognostic (3.00e-2)" "unprognostic (7.19e-3)" "unprognostic (1.03e-1)" "unprognostic (8.61e-2)" "unprognostic (3.25e-1)" "unprognostic (3.05e-2)" "unprognostic (2.24e-1)" "unprognostic (1.10e-3)" "unprognostic (1.62e-2)" "unprognostic (3.11e-2)" "unprognostic (5.90e-2)" "unprognostic (2.23e-1)" "potential prognostic unfavorable (7.06e-5)" "unprognostic (1.89e-2)" "unprognostic (1.94e-3)" "unprognostic (1.86e-1)" "unprognostic (1.59e-1)" "unprognostic (4.06e-2)" PDF ENSG00000258429 "Peptide deformylase, mitochondrial" Q9HBH1 16 69326913-69330588 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Protein biosynthesis" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 4.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063409 Approved Approved Nucleoplasm,Mitochondria "Intracellular and membrane" Enzyme No No "Cluster 45: Eosinophils - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 34: Non-specific - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 78: Plasma cells - Antibody production & ER-stress response" 11 Mitochondria Nucleoplasm "HPA063409: " "unprognostic (3.83e-2)" "unprognostic (5.84e-2)" "unprognostic (1.12e-1)" "unprognostic (1.40e-1)" "unprognostic (2.62e-1)" "unprognostic (1.31e-1)" "unprognostic (2.82e-1)" "unprognostic (1.49e-1)" "unprognostic (4.10e-3)" "unprognostic (7.51e-2)" "unprognostic (9.38e-2)" "unprognostic (3.02e-1)" "unprognostic (2.48e-3)" "unprognostic (1.50e-2)" "unprognostic (6.39e-2)" "unprognostic (3.63e-2)" "unprognostic (2.71e-2)" "unprognostic (4.82e-3)" "unprognostic (1.25e-1)" "unprognostic (1.95e-1)" "unprognostic (1.45e-2)" "unprognostic (2.06e-1)" "unprognostic (2.14e-1)" "unprognostic (5.17e-2)" "unprognostic (2.03e-2)" "unprognostic (2.00e-1)" "unprognostic (2.41e-1)" "unprognostic (9.00e-2)" "unprognostic (2.08e-1)" "unprognostic (9.31e-2)" "unprognostic (1.40e-1)" PDGFA "PDGF-A, PDGF1" ENSG00000197461 "Platelet derived growth factor subunit A" P04085 7 497258-520296 "Cancer-related genes, Candidate cardiovascular disease genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Developmental protein, Growth factor, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 101.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 138.5;Breast myoepithelial cells: 381.5;Pancreatic acinar cells: 399.9;Platelets: 609.9;Schwann cells: 156.3;Vascular smooth muscle cells: 193.3" "Cell type enhanced" "Detected in all" "vascular associated smooth muscle cell: 95.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 9.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005579, HPA065024" Approved Approved "Golgi apparatus" "Secreted to blood" "Growth factor" NA NA 260000 "Cluster 24: Non-specific - Transcription" "Cluster 24: Non-specific - Transcription" "Cluster 30: White matter - Myelination" "Cluster 67: Non-specific - Unknown function" "Cluster 103: Non-specific - Basic cellular processes" 5 "Golgi apparatus" "CAB005579: , HPA065024: " "unprognostic (7.03e-3)" "unprognostic (4.97e-2)" "unprognostic (1.82e-1)" "unprognostic (1.06e-1)" "unprognostic (8.15e-2)" "unprognostic (8.92e-2)" "unprognostic (1.72e-3)" "potential prognostic unfavorable (1.30e-4)" "potential prognostic unfavorable (2.08e-4)" "unprognostic (1.80e-1)" "unprognostic (1.42e-2)" "unprognostic (1.59e-2)" "unprognostic (3.69e-3)" "unprognostic (2.93e-3)" "unprognostic (1.76e-3)" "unprognostic (2.08e-1)" "unprognostic (1.91e-1)" "unprognostic (3.67e-3)" "unprognostic (1.11e-1)" "unprognostic (1.85e-1)" "unprognostic (9.54e-3)" "unprognostic (2.58e-1)" "unprognostic (1.79e-1)" "unprognostic (1.35e-1)" "unprognostic (1.01e-1)" "unprognostic (3.01e-1)" "unprognostic (4.39e-2)" "unprognostic (2.47e-2)" "unprognostic (1.95e-1)" "unprognostic (8.97e-2)" "unprognostic (9.40e-2)" PDGFB "SIS, SSV" ENSG00000100311 "Platelet derived growth factor subunit B" P01127 22 39223359-39244982 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Developmental protein, Growth factor, Mitogen" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "cDC: 34.9;Macrophages: 71.4;Megakaryocytes: 136.0;Microglia: 120.0;pDCs: 47.1;Platelets: 59.3;Salivary myoepithelial cells: 49.1;Schwann cells: 37.1;Vascular endothelial cells: 88.8" "Group enriched" "Detected in many" 4 "central nervous system macrophage: 160.4;endothelial cell: 165.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 10.0" "Lineage enriched" "Detected in many" 7 "T-cells: 10.0" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Colon - Enteric glia cells, Heart muscle - Endothelial cells, Prostate - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011604, HPA011972, CAB018341" Supported Approved Vesicles "Secreted to blood" "Growth factor" NA NA 4390000 760000 "Cluster 1: T-cells - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 17 Vesicles "CAB011604: , CAB018341: , HPA011972: " "unprognostic (3.71e-1)" "unprognostic (4.06e-2)" "unprognostic (3.52e-1)" "unprognostic (4.83e-3)" "unprognostic (2.76e-2)" "unprognostic (1.15e-2)" "unprognostic (2.81e-1)" "unprognostic (5.26e-1)" "unprognostic (2.24e-2)" "unprognostic (2.40e-1)" "validated prognostic favorable (4.90e-9)" "validated prognostic favorable (3.72e-5)" "unprognostic (4.04e-1)" "unprognostic (3.39e-1)" "unprognostic (2.21e-1)" "unprognostic (5.59e-3)" "potential prognostic unfavorable (9.81e-4)" "unprognostic (3.29e-3)" "unprognostic (1.63e-1)" "unprognostic (2.55e-1)" "unprognostic (1.34e-1)" "unprognostic (2.73e-1)" "unprognostic (7.50e-3)" "unprognostic (1.07e-1)" "unprognostic (7.21e-2)" "unprognostic (1.76e-1)" "unprognostic (1.31e-1)" "unprognostic (2.47e-2)" "unprognostic (1.80e-1)" "unprognostic (6.24e-2)" "unprognostic (1.01e-1)" PDGFC "fallotein, SCDGF" ENSG00000145431 "Platelet derived growth factor C" Q9NRA1 4 156760454-156971799 "Predicted secreted proteins, RAS pathway related proteins" "Developmental protein, Growth factor, Mitogen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 19.1" "Cell type enhanced" "Detected in many" "Macrophages: 387.3;Medullary thymic epithelial cells: 364.8;Proximal tubule cells: 410.0;Salivary acinar cells: 480.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Spleen - Macrophages, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA009134 Approved Supported "Plasma membrane,Cytosol" "Secreted to blood" "Growth factor" NA NA 48000 "Cluster 69: Parathyroid gland - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 5: Rhabdoid - Unknown function" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 3 "Plasma membrane, Cytosol" "HPA009134: " "unprognostic (2.48e-2)" "unprognostic (3.18e-1)" "unprognostic (5.06e-2)" "unprognostic (5.24e-2)" "unprognostic (3.65e-1)" "unprognostic (1.20e-1)" "unprognostic (3.12e-1)" "unprognostic (2.81e-2)" "unprognostic (2.62e-1)" "unprognostic (2.36e-1)" "validated prognostic favorable (5.03e-10)" "validated prognostic favorable (5.33e-5)" "unprognostic (2.16e-1)" "unprognostic (5.23e-2)" "unprognostic (1.29e-1)" "unprognostic (6.17e-2)" "unprognostic (6.40e-3)" "unprognostic (9.99e-2)" "unprognostic (1.69e-2)" "unprognostic (3.40e-3)" "potential prognostic unfavorable (3.94e-4)" "unprognostic (2.26e-1)" "unprognostic (2.31e-1)" "unprognostic (2.08e-1)" "unprognostic (5.33e-3)" "unprognostic (3.38e-2)" "unprognostic (2.81e-2)" "unprognostic (2.77e-2)" PDGFD "IEGF, MSTP036, SCDGF-B" ENSG00000170962 "Platelet derived growth factor D" Q9GZP0 11 103907189-104164379 "Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Developmental protein, Growth factor, Mitogen" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 100.6" "Group enriched" "Detected in many" 4 "Adrenal cortex cells: 2192.0;Pituitary stem cells: 2083.7" "Cell type enhanced" "Detected in many" "LAMP5-LHX6 and Chandelier: 461.1" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 39.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "eosinophil: 9.5;gdT-cell: 16.4;memory CD8 T-cell: 7.2;naive CD8 T-cell: 6.0;NK-cell: 17.1" "Group enriched" "Detected in many" 29 "granulocytes: 9.5;NK-cells: 17.1;T-cells: 16.4" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 51.0" "HPA046183, HPA066271" Approved Approved "Golgi apparatus,Vesicles" "Secreted to blood" "Growth factor" NA NA 26000 "Cluster 15: NK-cells - Unknown function" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 18: Adrenal cortex cells - Steroidogensis" "Golgi apparatus, Vesicles" "HPA046183: , HPA066271: " "unprognostic (1.12e-1)" "unprognostic (1.99e-1)" "unprognostic (2.62e-1)" "unprognostic (1.41e-1)" "unprognostic (1.63e-1)" "unprognostic (9.77e-2)" "unprognostic (1.23e-1)" "potential prognostic unfavorable (2.63e-4)" "unprognostic (3.17e-1)" "unprognostic (1.00e-1)" "validated prognostic favorable (4.90e-12)" "validated prognostic favorable (4.47e-5)" "unprognostic (7.41e-3)" "unprognostic (4.56e-2)" "unprognostic (1.55e-2)" "unprognostic (3.61e-2)" "unprognostic (2.27e-1)" "unprognostic (1.06e-2)" "unprognostic (4.80e-2)" "unprognostic (4.44e-2)" "potential prognostic unfavorable (2.42e-4)" "unprognostic (8.18e-2)" "unprognostic (1.32e-1)" "unprognostic (4.88e-1)" "unprognostic (4.82e-1)" "unprognostic (9.77e-2)" "unprognostic (2.38e-1)" "unprognostic (2.02e-3)" "unprognostic (9.95e-2)" "unprognostic (3.57e-2)" "unprognostic (2.44e-1)" PDGFRA "CD140a, GAS9, PDGFR2" ENSG00000134853 "Platelet derived growth factor receptor alpha" P16234 4 54229280-54298245 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Chemotaxis, Host-virus interaction" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 188.3" "Group enriched" "Detected in many" 4 "Decidual stromal cells: 203.7;Endometrial stromal cells: 261.4;Fibroblasts: 245.6;Hepatic stellate cells: 154.9;Leydig cells: 301.5;Oligodendrocyte progenitor cells: 296.2;Ovarian stromal cells: 108.6;Peritubular myoid cells: 333.9" "Group enriched" "Detected in some" 13 "fibroblast: 133.8;oligodendrocyte precursor cell: 320.9" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 101.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 78.7;thyroid cancer: 38.5" "Adrenal gland - Fibroblasts, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Minor Salivary Gland - Macrophages, Pituitary gland - Fibroblasts, Prostate - Fibroblasts, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004947, CAB018143" Supported Approved "Nucleoplasm,Nuclear bodies,Plasma membrane,Cell Junctions,Primary cilium,Cytosol" "Intracellular and membrane" Receptor NA NA 310000 "Cluster 75: Ovary - Mixed function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 36 "Nucleoplasm, Plasma membrane, Cell Junctions" "Nuclear bodies, Primary cilium, Cytosol" "CAB018143: , HPA004947: " "unprognostic (1.39e-1)" "unprognostic (2.75e-1)" "unprognostic (4.29e-1)" "unprognostic (3.15e-2)" "unprognostic (5.76e-2)" "unprognostic (9.07e-2)" "unprognostic (3.95e-1)" "unprognostic (8.34e-3)" "potential prognostic favorable (6.22e-5)" "unprognostic (2.31e-1)" "unprognostic (3.55e-2)" "unprognostic (3.37e-1)" "unprognostic (1.09e-3)" "unprognostic (7.37e-2)" "unprognostic (4.97e-3)" "unprognostic (1.86e-1)" "unprognostic (2.27e-1)" "unprognostic (1.51e-2)" "unprognostic (1.12e-1)" "unprognostic (1.17e-2)" "unprognostic (3.70e-3)" "unprognostic (9.86e-2)" "unprognostic (6.95e-2)" "unprognostic (8.35e-2)" "unprognostic (2.92e-1)" "unprognostic (3.93e-2)" "unprognostic (1.56e-2)" "unprognostic (6.53e-3)" "unprognostic (3.89e-2)" "unprognostic (1.59e-2)" "unprognostic (3.22e-2)" PDGFRB "CD140b, JTK12, PDGFR, PDGFR1" ENSG00000113721 "Platelet derived growth factor receptor beta" P09619 5 150113839-150155872 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" Chemotaxis "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 136.2;Bergmann glia: 139.0;Choroid plexus epithelial cells: 105.0;Decidual stromal cells: 113.4;Endometrial stromal cells: 107.5;Fibro-adipogenic progenitors: 192.6;Fibroblasts: 196.7;Hepatic stellate cells: 103.3;Leydig cells: 238.3;Pericytes: 779.9;Peritubular myoid cells: 293.7;Podocytes: 190.2;Vascular smooth muscle cells: 399.2" "Cell type enhanced" "Detected in many" "pericyte: 1272.1;vascular associated smooth muscle cell: 573.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.6" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 36.3;testis cancer: 35.2" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Adrenal gland - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003842, CAB018144, HPA028499" Enhanced Supported "Golgi apparatus,Vesicles" NA NA 9700000 "Cluster 33: Non-specific - ATP binding" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 23: Choroid plexus - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 110: Mural cells - ECM organization" 61 Vesicles "Golgi apparatus" "CAB003842: , CAB018144: , HPA028499: " "unprognostic (2.32e-2)" "unprognostic (5.35e-2)" "unprognostic (7.84e-2)" "unprognostic (2.84e-1)" "unprognostic (1.30e-2)" "unprognostic (2.92e-2)" "unprognostic (2.58e-1)" "unprognostic (3.22e-2)" "unprognostic (9.09e-2)" "unprognostic (4.05e-2)" "unprognostic (1.19e-2)" "unprognostic (1.21e-3)" "potential prognostic unfavorable (5.35e-5)" "unprognostic (1.18e-1)" "unprognostic (3.11e-1)" "unprognostic (1.88e-1)" "unprognostic (5.43e-3)" "unprognostic (1.67e-2)" "unprognostic (1.83e-1)" "unprognostic (3.85e-3)" "unprognostic (1.34e-3)" "unprognostic (5.78e-2)" "unprognostic (1.18e-1)" "unprognostic (2.50e-1)" "unprognostic (2.58e-1)" "unprognostic (2.00e-2)" "unprognostic (6.30e-3)" "unprognostic (7.20e-3)" "unprognostic (2.45e-2)" "unprognostic (9.92e-2)" "unprognostic (6.78e-2)" PDGFRL PRLTS ENSG00000104213 "Platelet derived growth factor receptor like" Q15198 8 17576433-17644071 "Disease related genes, Potential drug targets, Predicted secreted proteins, Transporters" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 61.7" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 70.7;Fibro-adipogenic progenitors: 108.4;Fibroblasts: 141.8;Hepatic stellate cells: 45.2;Leydig cells: 76.2;Oocytes: 317.8;Ovarian stromal cells: 54.2;Peritubular myoid cells: 69.9" "Cell type enhanced" "Detected in many" "LAMP5-LHX6 and Chandelier: 19.4" "Cancer enhanced" "Detected in all" "Thyroid Carcinoma (TCGA): 58.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Rhabdoid: 26.7" "Breast - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblasts_2, Skeletal muscle - Fibroblasts, Skin - Fibroblasts_2, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052801 Approved "Nucleoplasm,Nucleoli,Golgi apparatus" "Secreted - unknown location" "No annotated function" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 108: Fibroblasts - ECM organization" 3 "Nucleoli, Golgi apparatus" Nucleoplasm "HPA052801: " "unprognostic (2.29e-2)" "unprognostic (3.47e-1)" "unprognostic (2.48e-1)" "unprognostic (3.49e-2)" "unprognostic (1.65e-1)" "unprognostic (2.69e-2)" "unprognostic (1.11e-2)" "potential prognostic unfavorable (1.30e-4)" "unprognostic (1.45e-1)" "unprognostic (1.98e-1)" "potential prognostic unfavorable (5.78e-9)" "unprognostic (1.09e-3)" "potential prognostic unfavorable (1.65e-4)" "unprognostic (8.33e-2)" "potential prognostic unfavorable (8.32e-4)" "unprognostic (2.65e-1)" "unprognostic (5.67e-2)" "unprognostic (1.20e-1)" "unprognostic (1.33e-1)" "unprognostic (7.82e-3)" "unprognostic (5.03e-3)" "unprognostic (1.48e-1)" "unprognostic (1.59e-3)" "unprognostic (1.00e-1)" "unprognostic (7.22e-3)" "unprognostic (3.10e-1)" "unprognostic (2.59e-1)" "potential prognostic unfavorable (9.31e-4)" "unprognostic (1.41e-1)" "unprognostic (5.32e-2)" "unprognostic (1.49e-2)" PDHA1 "E1alpha, PDHA" ENSG00000131828 "Pyruvate dehydrogenase E1 subunit alpha 1" P08559 X 19343893-19361718 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism, Tricarboxylic acid cycle" Oxidoreductase "Disease variant, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 239.9;skeletal muscle: 209.1;tongue: 419.9" "Cell type enhanced" "Detected in many" "Oocytes: 690.8;Parietal cells: 284.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047487, HPA047864, HPA063053" Approved Supported Mitochondria NA NA 37000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 14: Neurons - Synaptic function" "Cluster 36: Non-specific - mRNA processing" "Cluster 97: Non-specific - Cellular respiration" 112 Mitochondria "HPA047487: , HPA047864: , HPA063053: " "unprognostic (2.12e-2)" "unprognostic (6.14e-3)" "unprognostic (1.99e-1)" "unprognostic (1.32e-1)" "unprognostic (1.71e-2)" "unprognostic (5.40e-3)" "unprognostic (2.82e-2)" "unprognostic (1.38e-2)" "unprognostic (5.78e-3)" "unprognostic (2.52e-2)" "potential prognostic favorable (5.75e-7)" "unprognostic (1.93e-1)" "potential prognostic favorable (6.01e-4)" "potential prognostic unfavorable (8.63e-4)" "unprognostic (1.80e-2)" "unprognostic (2.05e-2)" "unprognostic (5.88e-2)" "unprognostic (2.46e-2)" "unprognostic (3.85e-2)" "unprognostic (1.73e-1)" "unprognostic (5.10e-3)" "unprognostic (2.00e-1)" "unprognostic (2.85e-1)" "unprognostic (1.85e-2)" "unprognostic (9.35e-2)" "unprognostic (2.89e-1)" "unprognostic (3.30e-2)" "unprognostic (1.35e-1)" "unprognostic (3.54e-1)" "unprognostic (1.60e-2)" "unprognostic (3.54e-1)" PDHA2 PDHAL ENSG00000163114 "Pyruvate dehydrogenase E1 subunit alpha 2" P29803 4 95840093-95841464 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism, Tricarboxylic acid cycle" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 563 "testis: 56.2" "Group enriched" "Detected in some" 25 "Early spermatids: 370.6;Late primary spermatocytes: 666.6;Late spermatids: 362.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "HPA047487, HPA047864, HPA063053" Approved Supported Nucleoli,Mitochondria NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 1 Mitochondria Nucleoli "HPA047487: , HPA047864: , HPA063053: " PDHB "E1beta, PDHE1B" ENSG00000168291 "Pyruvate dehydrogenase E1 subunit beta" P11177 3 58427630-58433857 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism, Tricarboxylic acid cycle" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 279.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 205.1;Syncytiotrophoblasts: 176.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033794, HPA036744, HPA036745" Enhanced Supported "Nucleoplasm,Cell Junctions,Mitochondria" No No 26000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 97: Non-specific - Cellular respiration" 40 Mitochondria "Nucleoplasm, Cell Junctions" "CAB033794: , HPA036744: , HPA036745: " "unprognostic (1.01e-1)" "unprognostic (3.57e-2)" "unprognostic (2.18e-1)" "unprognostic (2.23e-1)" "unprognostic (2.45e-3)" "unprognostic (1.22e-1)" "unprognostic (2.11e-1)" "unprognostic (1.90e-1)" "unprognostic (9.15e-2)" "unprognostic (1.89e-2)" "potential prognostic favorable (5.19e-7)" "unprognostic (1.22e-2)" "potential prognostic favorable (1.52e-4)" "unprognostic (4.30e-2)" "unprognostic (1.16e-2)" "unprognostic (9.59e-2)" "unprognostic (4.54e-2)" "unprognostic (6.69e-2)" "unprognostic (4.93e-1)" "unprognostic (4.83e-2)" "unprognostic (2.11e-2)" "unprognostic (2.90e-1)" "unprognostic (4.88e-1)" "unprognostic (6.10e-2)" "unprognostic (2.75e-1)" "unprognostic (9.57e-2)" "unprognostic (5.37e-2)" "unprognostic (1.37e-1)" "unprognostic (1.65e-1)" "unprognostic (2.80e-2)" "unprognostic (4.07e-1)" PDHX "DLDBP, E3BP, OPDX, PDX1, proX" ENSG00000110435 "Pyruvate dehydrogenase complex component X" O00330 11 34915829-35020591 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 130.0;tongue: 116.9" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038484, HPA038485" Enhanced Approved "Nucleoplasm,Plasma membrane,Mitochondria" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 34: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 89: Adipocytes - Lipid metabolism" 17 "Nucleoplasm, Mitochondria" "Plasma membrane" "HPA038484: , HPA038485: " "unprognostic (1.19e-1)" "unprognostic (2.51e-1)" "unprognostic (6.74e-3)" "unprognostic (2.29e-1)" "unprognostic (7.89e-2)" "unprognostic (8.95e-2)" "unprognostic (5.24e-1)" "unprognostic (1.96e-2)" "unprognostic (2.58e-1)" "unprognostic (4.43e-2)" "potential prognostic favorable (7.00e-6)" "unprognostic (3.96e-3)" "unprognostic (6.12e-2)" "unprognostic (2.03e-2)" "unprognostic (6.23e-2)" "unprognostic (2.12e-2)" "unprognostic (9.56e-2)" "unprognostic (4.98e-2)" "unprognostic (1.16e-1)" "unprognostic (4.04e-1)" "unprognostic (1.03e-1)" "unprognostic (8.00e-2)" "unprognostic (3.59e-3)" "unprognostic (1.45e-1)" "unprognostic (4.23e-2)" "unprognostic (6.77e-2)" "unprognostic (4.28e-2)" "unprognostic (1.17e-1)" "unprognostic (1.86e-1)" "unprognostic (2.09e-1)" "unprognostic (2.12e-1)" PDIA2 "PDA2, PDI, PDIP, PDIR" ENSG00000185615 "Protein disulfide isomerase family A member 2" Q13087 16 283164-287215 "Enzymes, Predicted intracellular proteins" "Chaperone, Isomerase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "pancreas: 2364.1" "Group enriched" "Detected in some" 5 "Gastric chief cells: 579.9;Pancreatic acinar cells: 1557.9" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 4 "Pancreatic Adenocarcinoma (TCGA): 63.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 12.1;Myeloma: 26.1" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Stomach - Chief cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA051692, HPA053492" Enhanced "Intracellular and membrane" Enzyme NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 30: White matter - Myelination" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 5: Pancreatic acinar cells - Pancreatic exocrine secretion" 6 "HPA051692: , HPA053492: " "unprognostic (3.58e-2)" "unprognostic (2.22e-1)" "unprognostic (1.00e-1)" "unprognostic (6.15e-2)" "unprognostic (2.21e-1)" "unprognostic (1.74e-3)" "unprognostic (1.60e-2)" "unprognostic (6.26e-3)" "unprognostic (1.06e-2)" "unprognostic (1.93e-2)" "unprognostic (1.25e-1)" "unprognostic (1.03e-1)" "unprognostic (2.15e-2)" "unprognostic (2.15e-1)" "unprognostic (1.45e-2)" "unprognostic (8.18e-2)" "unprognostic (2.17e-1)" "unprognostic (4.19e-2)" "unprognostic (1.64e-2)" "unprognostic (1.28e-2)" "unprognostic (2.50e-2)" "unprognostic (2.64e-1)" "unprognostic (1.66e-1)" PDIA3 "ERp57, ERp60, ERp61, GRP57, GRP58, HsT17083, P58, PI-PLC" ENSG00000167004 "Protein disulfide isomerase family A member 3" P30101 15 43746394-43773279 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Adaptive immunity, Immunity" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 292.0" "Cell type enhanced" "Detected in all" "Epididymal principal cells: 1120.2;Extravillous trophoblasts: 1162.4;Syncytiotrophoblasts: 1401.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002645, HPA003230, CAB011199, CAB015181, CAB075744" Enhanced Enhanced "Endoplasmic reticulum" "Intracellular and membrane" Immunity NA NA 110000000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 22: Epididymis - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 8: Non-specific - Secretory pathway" 68 "Endoplasmic reticulum" "CAB011199: , CAB015181: , CAB075744: , HPA002645: , HPA003230: " "unprognostic (8.47e-2)" "unprognostic (1.95e-1)" "unprognostic (3.38e-1)" "unprognostic (1.44e-1)" "unprognostic (2.00e-1)" "unprognostic (1.26e-1)" "unprognostic (7.79e-3)" "unprognostic (9.72e-3)" "potential prognostic unfavorable (1.94e-4)" "unprognostic (3.99e-1)" "unprognostic (5.19e-3)" "potential prognostic unfavorable (6.14e-6)" "unprognostic (3.60e-2)" "unprognostic (4.25e-2)" "potential prognostic unfavorable (8.67e-4)" "unprognostic (8.35e-2)" "unprognostic (1.20e-1)" "unprognostic (1.43e-1)" "unprognostic (1.33e-1)" "unprognostic (1.04e-1)" "unprognostic (9.77e-2)" "unprognostic (9.50e-2)" "unprognostic (4.66e-3)" "unprognostic (2.70e-1)" "unprognostic (2.68e-1)" "unprognostic (6.38e-3)" "unprognostic (1.22e-1)" "unprognostic (4.64e-2)" "unprognostic (2.46e-1)" "unprognostic (2.81e-2)" "unprognostic (1.31e-1)" PDIA4 "ERP70, ERP72" ENSG00000155660 "Protein disulfide isomerase family A member 4" P13667 7 149003062-149028662 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 781.1;Extravillous trophoblasts: 537.5;Hepatocytes: 653.3;Plasma cells: 448.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006139, HPA006140, CAB017368" Supported Supported "Endoplasmic reticulum" "Intracellular and membrane" Enzyme NA NA 24000000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 70: Non-specific - Protein processing" "Cluster 55: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 8: Non-specific - Secretory pathway" 88 "Endoplasmic reticulum" "CAB017368: , HPA006139: , HPA006140: " "unprognostic (2.06e-2)" "unprognostic (8.89e-2)" "unprognostic (1.84e-1)" "unprognostic (4.78e-3)" "unprognostic (2.40e-2)" "unprognostic (9.75e-3)" "unprognostic (4.06e-3)" "unprognostic (2.12e-3)" "unprognostic (4.74e-2)" "unprognostic (1.04e-2)" "unprognostic (1.78e-3)" "potential prognostic unfavorable (5.10e-5)" "unprognostic (1.52e-3)" "unprognostic (8.56e-2)" "potential prognostic unfavorable (8.04e-4)" "unprognostic (1.25e-3)" "unprognostic (7.30e-3)" "unprognostic (1.34e-1)" "unprognostic (1.26e-1)" "unprognostic (1.85e-2)" "unprognostic (3.98e-1)" "unprognostic (3.47e-2)" "unprognostic (4.72e-1)" "unprognostic (4.75e-2)" "unprognostic (2.79e-1)" "unprognostic (1.34e-1)" "unprognostic (7.19e-3)" "unprognostic (2.01e-1)" "unprognostic (2.58e-1)" "unprognostic (3.60e-2)" "unprognostic (1.36e-1)" PDIA5 "FLJ30401, PDIR" ENSG00000065485 "Protein disulfide isomerase family A member 5" Q14554 3 123067025-123225227 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 75.0" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 250.1;Hepatocytes: 104.2;Megakaryocyte progenitors: 106.5" "Cell type enhanced" "Detected in all" "eccentric medium spiny neuron: 94.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 12.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Kidney - Endothelial cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Skeletal muscle - Endothelial cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030353, HPA030355" Enhanced Approved "Endoplasmic reticulum" "Intracellular and membrane" Enzyme NA NA 1700000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 23: Choroid plexus - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 8: Non-specific - Secretory pathway" 23 "Endoplasmic reticulum" "HPA030353: , HPA030355: " "unprognostic (7.90e-2)" "unprognostic (7.53e-2)" "unprognostic (1.60e-2)" "unprognostic (2.51e-2)" "unprognostic (1.68e-1)" "unprognostic (1.07e-1)" "unprognostic (7.39e-3)" "unprognostic (3.44e-1)" "unprognostic (1.99e-3)" "unprognostic (1.04e-2)" "unprognostic (1.29e-3)" "unprognostic (8.25e-2)" "unprognostic (1.00e-3)" "unprognostic (1.14e-2)" "unprognostic (2.96e-2)" "unprognostic (2.87e-1)" "unprognostic (2.47e-2)" "unprognostic (3.82e-2)" "unprognostic (1.62e-1)" "unprognostic (1.20e-1)" "unprognostic (1.62e-3)" "unprognostic (7.11e-2)" "unprognostic (2.02e-1)" "unprognostic (2.39e-3)" "unprognostic (1.04e-1)" "unprognostic (3.15e-1)" "unprognostic (9.51e-2)" "unprognostic (1.38e-1)" "unprognostic (1.54e-1)" "unprognostic (3.10e-3)" "unprognostic (1.51e-1)" PDIA6 "ERp5, P5, TXNDC7" ENSG00000143870 "Protein disulfide isomerase family A member 6" Q15084 2 10783391-10837977 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Chaperone, Isomerase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Decidual stromal cells: 733.6;Epididymal principal cells: 1039.1;Extravillous trophoblasts: 1634.6;Migrating cytotrophoblasts: 727.0;Plasma cells: 859.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Macrophages, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034347, HPA034652, HPA034653" Enhanced Supported "Endoplasmic reticulum,Primary cilium,Centriolar satellite,Basal body" "Intracellular and membrane" Enzyme NA NA 14000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 22: Epididymis - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 8: Non-specific - Secretory pathway" 31 "Endoplasmic reticulum" "Primary cilium, Centriolar satellite, Basal body" "CAB034347: , HPA034652: , HPA034653: " "unprognostic (1.06e-1)" "unprognostic (8.69e-3)" "unprognostic (2.84e-1)" "potential prognostic unfavorable (6.15e-4)" "unprognostic (1.11e-1)" "unprognostic (3.04e-2)" "unprognostic (6.09e-2)" "unprognostic (1.76e-3)" "potential prognostic unfavorable (7.46e-4)" "potential prognostic unfavorable (1.79e-4)" "potential prognostic favorable (5.18e-4)" "unprognostic (2.02e-3)" "unprognostic (6.07e-3)" "validated prognostic unfavorable (1.13e-7)" "validated prognostic unfavorable (1.04e-6)" "unprognostic (4.95e-3)" "unprognostic (4.61e-2)" "unprognostic (1.59e-1)" "unprognostic (8.48e-2)" "unprognostic (2.01e-3)" "unprognostic (3.93e-2)" "potential prognostic unfavorable (5.25e-4)" "unprognostic (9.26e-3)" "unprognostic (2.58e-1)" "unprognostic (2.08e-1)" "unprognostic (1.34e-2)" "potential prognostic unfavorable (8.04e-5)" "unprognostic (3.27e-1)" "unprognostic (1.71e-1)" "unprognostic (2.47e-2)" "unprognostic (1.79e-1)" PDIK1L CLIK1L ENSG00000175087 "PDLIM1 interacting kinase 1 like" Q8N165 1 26111165-26125555 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Myonuclei: 54.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064157 Supported Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 17 Nucleoplasm "HPA064157: " "unprognostic (1.25e-2)" "unprognostic (3.01e-2)" "unprognostic (4.20e-2)" "unprognostic (7.61e-2)" "unprognostic (4.34e-3)" "unprognostic (1.53e-1)" "unprognostic (2.38e-1)" "unprognostic (5.68e-3)" "unprognostic (6.56e-3)" "unprognostic (1.68e-2)" "potential prognostic favorable (1.67e-5)" "unprognostic (1.76e-3)" "unprognostic (4.17e-2)" "unprognostic (5.06e-2)" "unprognostic (3.66e-2)" "unprognostic (1.30e-2)" "unprognostic (2.43e-1)" "unprognostic (2.15e-1)" "unprognostic (1.14e-3)" "unprognostic (3.40e-1)" "unprognostic (1.84e-2)" "unprognostic (2.80e-2)" "unprognostic (8.85e-3)" "unprognostic (1.44e-1)" "unprognostic (1.81e-1)" "unprognostic (2.06e-1)" "unprognostic (2.26e-2)" "unprognostic (1.13e-2)" "unprognostic (1.61e-2)" "unprognostic (2.22e-1)" "unprognostic (1.59e-2)" PDILT PDIA7 ENSG00000169340 "Protein disulfide isomerase like, testis expressed" Q8N807 16 20359175-20404737 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Chaperone, Developmental protein, Isomerase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "stomach 1: 116.9" "Group enriched" "Detected in some" 4 "Early spermatids: 224.2;Gastric chief cells: 69.9;Late primary spermatocytes: 87.0" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 2.8" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA041913 Approved "Intracellular and membrane" "Developmental protein" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 21: Testis - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" "HPA041913: " "unprognostic (4.48e-1)" PDK1 ENSG00000152256 "Pyruvate dehydrogenase kinase 1" Q15118 2 172555373-172608669 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 168.9;Plasma cells: 297.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 5 "B-cells: 8.6;granulocytes: 25.2;T-cells: 21.3" "Cancer enhanced" "Detected in all" "Myeloma: 69.6" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Plasma cells, Spleen - Plasma cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017554, HPA027376, HPA059083" Supported NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 2: Neurons - Nucleosome" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 67: Plasma cells - Plasma cell differentiation" 40 "CAB017554: , HPA027376: , HPA059083: " "unprognostic (5.34e-2)" "unprognostic (1.48e-1)" "unprognostic (9.63e-2)" "potential prognostic unfavorable (1.61e-6)" "unprognostic (3.59e-1)" "unprognostic (6.36e-3)" "unprognostic (1.59e-2)" "unprognostic (7.83e-2)" "unprognostic (4.12e-1)" "potential prognostic unfavorable (1.25e-4)" "potential prognostic favorable (1.02e-6)" "unprognostic (1.22e-2)" "unprognostic (2.04e-2)" "unprognostic (1.21e-2)" "unprognostic (1.35e-2)" "unprognostic (3.76e-2)" "unprognostic (7.67e-2)" "unprognostic (2.57e-1)" "unprognostic (1.46e-3)" "unprognostic (1.06e-1)" "unprognostic (1.80e-2)" "unprognostic (6.67e-3)" "potential prognostic unfavorable (3.66e-4)" "unprognostic (2.48e-1)" "unprognostic (1.34e-1)" "unprognostic (1.79e-1)" "unprognostic (9.30e-2)" "unprognostic (1.75e-1)" "unprognostic (4.34e-1)" "unprognostic (1.22e-2)" "unprognostic (3.05e-1)" PDK2 PDHK2 ENSG00000005882 "Pyruvate dehydrogenase kinase 2" Q15119 17 50094737-50112152 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 202.5;tongue: 265.8" "Cell type enhanced" "Detected in many" "Enterocytes: 113.5;Epididymal principal cells: 248.9;Retinal pigment epithelial cells: 110.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Spleen - Fibroblasts_2, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008287 Supported Approved Nucleoplasm,Mitochondria NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 15: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 7 "Nucleoplasm, Mitochondria" "HPA008287: " "unprognostic (1.36e-1)" "unprognostic (8.49e-2)" "unprognostic (1.29e-1)" "unprognostic (3.35e-3)" "unprognostic (1.50e-1)" "unprognostic (6.93e-2)" "unprognostic (4.34e-1)" "unprognostic (2.77e-2)" "unprognostic (6.61e-3)" "unprognostic (3.36e-1)" "validated prognostic favorable (1.42e-6)" "validated prognostic favorable (7.17e-5)" "unprognostic (2.08e-3)" "unprognostic (3.00e-2)" "unprognostic (2.84e-2)" "potential prognostic favorable (5.32e-4)" "unprognostic (1.94e-1)" "unprognostic (1.47e-1)" "unprognostic (7.91e-2)" "unprognostic (1.47e-1)" "unprognostic (3.30e-1)" "unprognostic (1.21e-1)" "unprognostic (2.92e-2)" "unprognostic (8.27e-2)" "unprognostic (1.18e-1)" "unprognostic (1.17e-1)" "unprognostic (9.77e-2)" "unprognostic (2.68e-1)" "unprognostic (1.31e-1)" "unprognostic (2.69e-1)" "unprognostic (1.97e-1)" PDK3 ENSG00000067992 "Pyruvate dehydrogenase kinase 3" Q15120 X 24465244-24550466 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 33.6" "Cell type enhanced" "Detected in many" "Lacrimal acinar cells: 261.8;Neutrophils: 200.7;Sertoli cells: 335.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046583, HPA072492" Approved Supported Nucleoli,Mitochondria NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 14: Neurons - Synaptic function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 27 Mitochondria Nucleoli "HPA046583: , HPA072492: " "unprognostic (6.29e-2)" "potential prognostic unfavorable (2.69e-5)" "unprognostic (7.06e-2)" "unprognostic (9.88e-2)" "unprognostic (2.87e-2)" "unprognostic (1.64e-1)" "unprognostic (4.31e-2)" "unprognostic (1.16e-2)" "unprognostic (2.40e-2)" "potential prognostic unfavorable (8.49e-5)" "potential prognostic favorable (3.47e-6)" "unprognostic (3.17e-2)" "unprognostic (2.36e-1)" "potential prognostic unfavorable (1.80e-4)" "unprognostic (5.68e-2)" "unprognostic (1.55e-1)" "potential prognostic unfavorable (1.27e-4)" "unprognostic (1.62e-1)" "unprognostic (3.75e-1)" "unprognostic (1.34e-1)" "unprognostic (1.81e-1)" "unprognostic (6.03e-2)" "unprognostic (1.43e-2)" "unprognostic (9.66e-2)" "unprognostic (8.15e-3)" "unprognostic (9.23e-3)" "unprognostic (3.46e-2)" "unprognostic (5.18e-2)" "unprognostic (7.88e-2)" "unprognostic (3.06e-1)" "unprognostic (2.10e-1)" PDK4 ENSG00000004799 "Pyruvate dehydrogenase kinase 4" Q16654 7 95583499-95596516 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 2154.8;tongue: 1137.3" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 915.7;Enterocytes: 1814.4;Epididymal basal cells: 846.7;Epididymal efferent duct absorptive cells: 1709.1;Epididymal efferent duct ciliated cells: 1133.6;Kupffer cells: 1538.4;Salivary acinar cells: 877.9;Thymic myoid cells: 3567.7;Vascular smooth muscle cells: 856.3" "Cell type enhanced" "Detected in many" "astrocyte: 151.4;choroid plexus epithelial cell: 410.2" "Group enriched" "Detected in all" 4 "Kidney Renal Clear Cell Carcinoma (TCGA): 304.6;Thyroid Carcinoma (TCGA): 166.3" "Region enriched" "Detected in all" 5 "choroid plexus: 437.8" "Group enriched" "Detected in many" 11 "classical monocyte: 32.5;eosinophil: 38.2;intermediate monocyte: 63.5;myeloid DC: 16.7;non-classical monocyte: 39.9" "Group enriched" "Detected in many" 12 "dendritic cells: 16.7;granulocytes: 38.2;monocytes: 63.5" "Cancer enhanced" "Detected in many" "skin cancer: 17.8" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056731 Approved NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 36: Choroid plexus - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 103: Non-specific - Basic cellular processes" 2 "HPA056731: " "unprognostic (1.34e-1)" "unprognostic (1.07e-2)" "unprognostic (1.11e-2)" "potential prognostic favorable (2.77e-4)" "unprognostic (6.81e-2)" "unprognostic (5.87e-2)" "unprognostic (1.66e-1)" "unprognostic (9.33e-3)" "unprognostic (1.18e-1)" "unprognostic (1.48e-1)" "potential prognostic favorable (1.73e-12)" "unprognostic (1.32e-2)" "potential prognostic unfavorable (4.73e-4)" "validated prognostic favorable (6.75e-4)" "validated prognostic favorable (2.62e-4)" "unprognostic (1.59e-1)" "unprognostic (4.17e-2)" "unprognostic (1.78e-2)" "unprognostic (2.95e-1)" "unprognostic (1.64e-3)" "unprognostic (4.82e-2)" "unprognostic (3.20e-2)" "unprognostic (1.96e-1)" "unprognostic (1.20e-1)" "unprognostic (2.79e-1)" "unprognostic (6.61e-2)" "unprognostic (1.52e-1)" "potential prognostic unfavorable (2.10e-4)" "unprognostic (1.66e-1)" "unprognostic (2.97e-2)" "unprognostic (2.52e-1)" PDLIM1 "CLIM1, CLP-36, CLP36, hCLIM1" ENSG00000107438 "PDZ and LIM domain 1" O00151 10 95237572-95291012 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 652.8" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 1111.6;Enterocytes: 1047.8;Megakaryocytes: 2083.2;Platelets: 1473.2" "Cell type enhanced" "Detected in many" "endothelial cell: 74.5;fibroblast: 57.8;vascular associated smooth muscle cell: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "eosinophil: 190.2;memory B-cell: 224.6;naive B-cell: 213.9" "Group enriched" "Detected in all" 7 "B-cells: 224.6;granulocytes: 190.2" "Low cancer specificity" "Detected in all" "Pituitary gland - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017010, CAB072838, CAB072840" Approved Supported "Plasma membrane,Cell Junctions,Actin filaments" NA NA 85000000 "Cluster 22: Eosinophils - Transcription" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 47: Platelets - Hemostasis" 28 "Actin filaments" "Plasma membrane, Cell Junctions" "CAB072838: , CAB072840: , HPA017010: " "unprognostic (2.36e-3)" "unprognostic (1.59e-1)" "unprognostic (1.40e-1)" "unprognostic (9.29e-2)" "unprognostic (7.60e-2)" "unprognostic (7.63e-2)" "unprognostic (1.40e-2)" "unprognostic (1.07e-2)" "unprognostic (4.91e-2)" "unprognostic (1.91e-1)" "potential prognostic favorable (1.99e-5)" "unprognostic (1.20e-1)" "unprognostic (1.67e-2)" "unprognostic (6.61e-2)" "unprognostic (2.02e-2)" "unprognostic (4.22e-1)" "potential prognostic unfavorable (4.17e-5)" "unprognostic (1.99e-1)" "unprognostic (1.22e-2)" "unprognostic (6.27e-2)" "unprognostic (6.01e-2)" "unprognostic (4.88e-2)" "unprognostic (1.36e-1)" "unprognostic (5.20e-2)" "unprognostic (6.39e-2)" "unprognostic (2.82e-1)" "unprognostic (4.99e-2)" "unprognostic (2.72e-2)" "unprognostic (2.70e-1)" "unprognostic (4.83e-2)" "unprognostic (1.84e-2)" PDLIM2 ENSG00000120913 "PDZ and LIM domain 2" Q96JY6 8 22578279-22598025 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 11.7;Bergmann glia: 17.2;Brain excitatory neurons: 12.9;Enterocytes: 18.5;Ependymal cells: 8.3;Microglia: 7.7;Oligodendrocyte progenitor cells: 8.6;Other brain neurons: 8.8;Podocytes: 11.6;Syncytiotrophoblasts: 7.3;Transitional alveolar cells: 8.1" "Cell type enhanced" "Detected in many" "pericyte: 108.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Adrenal gland - Fibroblasts, Breast - Fibroblasts, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Stomach - Fibroblasts" "Region enhanced" "Detected in all" "white matter: 429.4" "Low region specificity" "Detected in many" HPA003880 Approved Supported "Actin filaments,Focal adhesion sites" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 22: Non-specific - Basic cellular functions" 3 "Actin filaments, Focal adhesion sites" "HPA003880: " "unprognostic (4.96e-2)" "unprognostic (1.50e-1)" "unprognostic (1.68e-1)" "unprognostic (1.26e-1)" "unprognostic (8.15e-2)" "unprognostic (5.42e-2)" "unprognostic (2.02e-2)" "unprognostic (2.43e-1)" "unprognostic (6.11e-2)" "unprognostic (2.12e-1)" "unprognostic (3.38e-3)" "unprognostic (1.64e-1)" "potential prognostic unfavorable (4.46e-6)" "unprognostic (2.97e-1)" "potential prognostic favorable (9.07e-4)" "unprognostic (9.59e-2)" "unprognostic (7.48e-2)" "unprognostic (6.89e-2)" "unprognostic (3.90e-1)" "unprognostic (1.97e-3)" "unprognostic (6.90e-2)" "unprognostic (1.73e-1)" "unprognostic (1.12e-1)" "unprognostic (1.21e-1)" "unprognostic (4.51e-2)" "unprognostic (6.59e-2)" "unprognostic (4.71e-2)" "unprognostic (2.91e-1)" "unprognostic (9.39e-2)" "unprognostic (1.71e-1)" "unprognostic (3.89e-2)" PDLIM3 ALP ENSG00000154553 "PDZ and LIM domain 3" Q53GG5 4 185500660-185535507 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "skeletal muscle: 3108.5;tongue: 958.8" "Cell type enhanced" "Detected in many" "Bergmann glia: 407.8;Myonuclei: 4134.7;Myosatellite cells: 433.9;Salivary myoepithelial cells: 520.1;Smooth muscle cells: 1114.2;Thymic myoid cells: 726.0;Vascular smooth muscle cells: 357.6" "Cell type enhanced" "Detected in many" "Bergmann glia: 446.7;vascular associated smooth muscle cell: 218.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 25.2;Sarcoma: 27.5" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Smooth muscle cells, Breast - Breast myoepithelial cells, Colon - Smooth muscle cells, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Skin - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004749 Enhanced Supported Cytosol NA NA 300000 "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 44: Non-specific - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 4 Cytosol "HPA004749: " "unprognostic (1.06e-2)" "unprognostic (2.26e-1)" "unprognostic (4.80e-2)" "unprognostic (5.81e-2)" "unprognostic (9.66e-2)" "unprognostic (1.77e-2)" "unprognostic (3.61e-3)" "unprognostic (1.04e-3)" "unprognostic (1.23e-2)" "unprognostic (3.38e-2)" "unprognostic (1.69e-2)" "unprognostic (3.61e-1)" "unprognostic (2.56e-1)" "unprognostic (1.51e-3)" "unprognostic (2.37e-1)" "unprognostic (5.17e-2)" "unprognostic (5.20e-2)" "unprognostic (2.90e-3)" "unprognostic (1.24e-3)" "unprognostic (7.59e-2)" "unprognostic (5.19e-3)" "unprognostic (9.02e-2)" "unprognostic (1.53e-1)" "unprognostic (1.11e-1)" "unprognostic (1.63e-2)" "unprognostic (1.03e-1)" "unprognostic (2.90e-1)" "unprognostic (1.22e-3)" "unprognostic (1.35e-1)" "potential prognostic unfavorable (3.16e-6)" "unprognostic (2.40e-2)" PDLIM4 RIL ENSG00000131435 "PDZ and LIM domain 4" P50479 5 132257696-132273454 "Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 428.8;Decidual stromal cells: 264.5;Epididymal principal cells: 158.5;Esophageal apical cells: 199.0;Esophageal basal cells: 151.6;Esophageal suprabasal cells: 184.4;Respiratory ciliated cells: 157.8;Schwann cells: 190.7;Smooth muscle cells: 215.1;Submucosal glandular cells: 185.2" "Group enriched" "Detected in many" 5 "astrocyte: 20.6;Bergmann glia: 9.2;choroid plexus epithelial cell: 13.9;endothelial cell: 10.7;ependymal cell: 15.3;fibroblast: 15.6;pericyte: 8.6;vascular associated smooth muscle cell: 5.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Smooth muscle cells, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011912, HPA073227" Uncertain Supported "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 39: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 5 "Actin filaments" "Plasma membrane, Cytosol" "HPA011912: , HPA073227: " "unprognostic (1.29e-1)" "unprognostic (1.15e-3)" "unprognostic (9.66e-2)" "unprognostic (1.62e-1)" "unprognostic (2.74e-3)" "unprognostic (1.35e-1)" "unprognostic (4.82e-3)" "potential prognostic unfavorable (8.48e-7)" "unprognostic (3.13e-3)" "unprognostic (1.23e-1)" "unprognostic (5.81e-2)" "unprognostic (3.34e-1)" "unprognostic (4.08e-3)" "unprognostic (1.84e-1)" "unprognostic (4.41e-2)" "unprognostic (2.85e-2)" "potential prognostic unfavorable (2.94e-4)" "unprognostic (3.02e-1)" "unprognostic (3.72e-1)" "unprognostic (1.45e-2)" "unprognostic (8.34e-2)" "unprognostic (3.66e-1)" "unprognostic (1.39e-2)" "unprognostic (1.57e-3)" "unprognostic (1.74e-1)" "unprognostic (5.10e-3)" "unprognostic (6.36e-2)" "unprognostic (8.50e-3)" "unprognostic (2.84e-1)" "unprognostic (1.21e-2)" "unprognostic (1.21e-1)" PDLIM5 "Enh, LIM" ENSG00000163110 "PDZ and LIM domain 5" Q96HC4 4 94451857-94668227 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "heart muscle: 589.2;skeletal muscle: 1089.9;tongue: 538.0" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 2747.2;Myonuclei: 5563.8;Pituicytes/FSCs: 1558.6" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 737.0;vascular associated smooth muscle cell: 1322.3" "Cancer enriched" "Detected in all" 7 "Prostate Adenocarcinoma (TCGA): 356.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "basophil: 217.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 217.8" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Lung - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013511, HPA016740, HPA020026" Enhanced Approved "Nucleoplasm,Plasma membrane,Focal adhesion sites" NA NA 1500000 "Cluster 32: Basophils - Transcription" "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 8: Immune cells - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 55: Myocytes - Oxidative muscle function" 27 "Plasma membrane" "Nucleoplasm, Focal adhesion sites" "CAB013511: , HPA016740: , HPA020026: " "unprognostic (5.86e-2)" "unprognostic (1.02e-1)" "unprognostic (2.28e-1)" "unprognostic (1.44e-2)" "unprognostic (5.28e-2)" "unprognostic (9.02e-3)" "unprognostic (3.49e-2)" "unprognostic (1.36e-1)" "unprognostic (4.10e-1)" "potential prognostic unfavorable (3.20e-4)" "potential prognostic favorable (4.62e-5)" "unprognostic (1.68e-2)" "unprognostic (4.75e-1)" "unprognostic (5.01e-2)" "unprognostic (1.83e-2)" "unprognostic (5.75e-3)" "unprognostic (2.42e-2)" "unprognostic (1.25e-1)" "unprognostic (2.41e-1)" "unprognostic (3.40e-2)" "unprognostic (1.90e-2)" "unprognostic (1.84e-2)" "unprognostic (1.66e-1)" "unprognostic (3.67e-1)" "unprognostic (3.40e-1)" "unprognostic (1.82e-1)" "unprognostic (2.18e-2)" "unprognostic (2.69e-2)" "unprognostic (1.63e-1)" "unprognostic (6.02e-2)" "unprognostic (1.29e-1)" PDLIM7 ENIGMA ENSG00000196923 "PDZ and LIM domain 7" Q9NR12 5 177483394-177497606 "Predicted intracellular proteins" "Differentiation, Osteogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 549.7;intestine: 568.3;skeletal muscle: 620.5" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 252.3;Decidual stromal cells: 379.9;Hepatic stellate cells: 213.0;Megakaryocytes: 321.4;Neutrophils: 246.2;Peritubular myoid cells: 289.6;Platelets: 255.0;Smooth muscle cells: 511.7;Vascular smooth muscle cells: 232.3" "Cell type enhanced" "Detected in all" "vascular associated smooth muscle cell: 131.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 178.3;eosinophil: 121.5;neutrophil: 440.6" "Lineage enriched" "Detected in all" 9 "granulocytes: 440.6" "Low cancer specificity" "Detected in all" "Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018794, HPA048815" Approved Enhanced "Actin filaments,Focal adhesion sites" NA NA 1600000 "Cluster 21: Neutrophils - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 62: Smooth muscle cells - Muscle contraction" 67 "Actin filaments, Focal adhesion sites" "HPA018794: , HPA048815: " "unprognostic (6.82e-2)" "unprognostic (1.68e-2)" "unprognostic (1.85e-1)" "unprognostic (1.54e-2)" "unprognostic (9.18e-3)" "unprognostic (2.83e-2)" "unprognostic (5.30e-2)" "unprognostic (2.53e-1)" "unprognostic (1.54e-2)" "unprognostic (7.50e-3)" "unprognostic (1.10e-3)" "unprognostic (8.94e-3)" "unprognostic (9.63e-3)" "unprognostic (5.13e-3)" "unprognostic (2.51e-1)" "validated prognostic unfavorable (2.42e-4)" "validated prognostic unfavorable (5.27e-4)" "unprognostic (2.07e-3)" "unprognostic (4.89e-2)" "unprognostic (1.29e-1)" "unprognostic (4.76e-1)" "unprognostic (5.03e-2)" "unprognostic (1.68e-2)" "unprognostic (8.80e-2)" "unprognostic (7.65e-2)" "unprognostic (1.39e-2)" "unprognostic (3.86e-3)" "unprognostic (8.39e-3)" "unprognostic (3.62e-1)" "unprognostic (3.97e-2)" "unprognostic (5.39e-2)" PDP1 "PDH, PDP, PPM2A, PPM2C" ENSG00000164951 "Pyruvate dehydrogenase phosphatase catalytic subunit 1" Q9P0J1 8 93857807-93926068 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 165.4;Cardiomyocytes: 107.2;Early spermatids: 177.8;Endometrial glandular cells: 93.3;Ocular epithelial cells: 90.6;Salivary duct cells: 95.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Vascular endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018483, HPA019081, HPA021152" Uncertain Uncertain Nucleoplasm,Vesicles,Mitochondria,Cytosol Yes No "Cluster 33: Non-specific - ATP binding" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 53: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 100: Stratified epithelial cells - Barrier functions" 8 "Nucleoplasm, Cytosol" "Vesicles, Mitochondria" "HPA018483: , HPA019081: , HPA021152: " "unprognostic (2.63e-2)" "potential prognostic unfavorable (2.63e-5)" "unprognostic (3.14e-1)" "unprognostic (2.70e-2)" "unprognostic (1.50e-1)" "unprognostic (2.99e-1)" "unprognostic (1.90e-1)" "unprognostic (7.15e-2)" "unprognostic (1.51e-1)" "unprognostic (1.44e-1)" "potential prognostic favorable (8.42e-6)" "unprognostic (1.56e-2)" "unprognostic (7.50e-3)" "unprognostic (1.69e-1)" "unprognostic (1.54e-1)" "unprognostic (2.17e-1)" "unprognostic (1.46e-2)" "unprognostic (7.61e-2)" "unprognostic (4.40e-1)" "validated prognostic unfavorable (1.11e-5)" "validated prognostic unfavorable (2.34e-4)" "unprognostic (8.36e-3)" "unprognostic (2.66e-3)" "unprognostic (2.56e-1)" "unprognostic (5.82e-2)" "unprognostic (1.08e-1)" "unprognostic (1.53e-1)" "unprognostic (9.23e-2)" "unprognostic (2.52e-1)" "unprognostic (1.71e-1)" "unprognostic (3.06e-2)" PDP2 "KIAA1348, PPM2B, PPM2C2" ENSG00000172840 "Pyruvate dehydrogenase phosphatase catalytic subunit 2" Q9P2J9 16 66878589-66895754 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 31.9;Alveolar cells type 2: 33.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Lung - Alveolar cells type 2, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019950, HPA062059" Approved Approved Mitochondria NA NA "Cluster 1: T-cells - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 81: Alveolar cells - Lung function" 1 Mitochondria "HPA019950: , HPA062059: " "unprognostic (3.80e-1)" "unprognostic (4.30e-2)" "unprognostic (2.66e-1)" "potential prognostic unfavorable (3.71e-4)" "unprognostic (4.80e-1)" "unprognostic (1.19e-1)" "unprognostic (1.14e-1)" "unprognostic (1.15e-1)" "unprognostic (4.37e-2)" "unprognostic (4.52e-2)" "potential prognostic favorable (5.24e-5)" "unprognostic (4.28e-2)" "unprognostic (1.39e-1)" "unprognostic (1.91e-2)" "unprognostic (2.22e-2)" "unprognostic (4.00e-2)" "unprognostic (4.18e-1)" "unprognostic (3.27e-2)" "unprognostic (1.89e-2)" "unprognostic (1.53e-1)" "unprognostic (2.36e-3)" "unprognostic (4.83e-2)" "unprognostic (1.21e-1)" "unprognostic (1.23e-1)" "unprognostic (2.72e-3)" "unprognostic (2.76e-1)" "unprognostic (1.68e-2)" "unprognostic (4.78e-2)" "unprognostic (3.89e-1)" "unprognostic (1.66e-1)" "unprognostic (6.75e-2)" PDPK1 PDK1 ENSG00000140992 "3-phosphoinositide dependent protein kinase 1" O15530 16 2537979-2603188 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 184.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004272, HPA008062, HPA035199" Supported Enhanced "Primary cilium tip,Cytosol" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 33: Neurons - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 105: Non-specific - Mixed function" 54 Cytosol "Primary cilium tip" "CAB004272: , HPA008062: , HPA035199: " "unprognostic (2.30e-2)" "unprognostic (1.39e-2)" "unprognostic (4.04e-1)" "unprognostic (3.40e-2)" "unprognostic (5.36e-2)" "unprognostic (5.66e-2)" "unprognostic (1.04e-1)" "unprognostic (4.43e-2)" "unprognostic (1.87e-3)" "unprognostic (4.18e-1)" "potential prognostic favorable (1.98e-8)" "unprognostic (1.32e-3)" "unprognostic (7.76e-3)" "unprognostic (1.15e-1)" "unprognostic (4.89e-2)" "unprognostic (9.46e-3)" "unprognostic (8.44e-2)" "unprognostic (3.18e-2)" "unprognostic (8.00e-2)" "unprognostic (5.05e-3)" "unprognostic (4.76e-3)" "unprognostic (3.21e-2)" "unprognostic (6.98e-2)" "unprognostic (2.44e-1)" "unprognostic (2.98e-2)" "unprognostic (6.50e-2)" "unprognostic (9.37e-2)" "unprognostic (7.65e-2)" "unprognostic (1.80e-1)" "unprognostic (1.02e-1)" "unprognostic (2.16e-1)" PDPN "aggrus, D2-40, Gp38, GP40, PA2.26, T1A-2" ENSG00000162493 Podoplanin Q86YL7 1 13583465-13617957 "Predicted membrane proteins, Transporters" "Cell shape" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 127.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 108.9;Breast myoepithelial cells: 85.2;Decidual stromal cells: 204.4;Epicardial cells: 170.6;Epididymal basal cells: 98.5;Fibroblasts: 145.2;Lymphatic endothelial cells: 175.0;Mesothelial cells: 167.1;Müller glia: 119.6;Oocytes: 92.1;Ovarian stromal cells: 93.2;Peritubular myoid cells: 72.0;Retinal pigment epithelial cells: 102.3;Salivary myoepithelial cells: 95.0" "Group enriched" "Detected in many" 6 "astrocyte: 19.5;Bergmann glia: 26.1;central nervous system macrophage: 31.6;choroid plexus epithelial cell: 40.0;ependymal cell: 24.2;fibroblast: 21.6;oligodendrocyte precursor cell: 40.4" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 216.3;Testicular Germ Cell Tumor (TCGA): 288.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 109.6;thyroid cancer: 97.5" "Kidney - Podocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007534, HPA007949, CAB008376" Enhanced Supported "Plasma membrane,Cell Junctions,Mitochondria" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 12: Non-specific - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 103: Non-specific - Basic cellular processes" 1 "Plasma membrane" "Cell Junctions, Mitochondria" "CAB008376: , HPA007534: , HPA007949: " "unprognostic (1.31e-2)" "unprognostic (2.88e-1)" "unprognostic (5.46e-2)" "unprognostic (4.03e-2)" "unprognostic (3.82e-2)" "unprognostic (1.83e-1)" "unprognostic (3.41e-2)" "potential prognostic unfavorable (4.86e-7)" "unprognostic (3.34e-3)" "unprognostic (5.73e-2)" "unprognostic (4.78e-3)" "unprognostic (1.93e-2)" "unprognostic (1.83e-1)" "unprognostic (2.23e-2)" "unprognostic (1.70e-1)" "unprognostic (1.50e-1)" "unprognostic (4.54e-2)" "unprognostic (6.44e-2)" "unprognostic (1.29e-1)" "unprognostic (5.75e-2)" "unprognostic (2.17e-2)" "unprognostic (1.07e-2)" "unprognostic (2.60e-1)" "unprognostic (6.07e-2)" "unprognostic (3.95e-1)" "unprognostic (5.39e-3)" "unprognostic (1.12e-1)" "potential prognostic unfavorable (5.24e-4)" "unprognostic (1.80e-1)" "unprognostic (2.88e-2)" "unprognostic (3.14e-2)" PDPR PDP3 ENSG00000090857 "Pyruvate dehydrogenase phosphatase regulatory subunit" Q8NCN5 16 70114332-70162537 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048092, HPA070386" Uncertain Approved Mitochondria NA NA "Cluster 32: Basophils - Transcription" "Cluster 67: Testis - Mixed function" "Cluster 25: Non-specific - Transcription" "Cluster 11: Neuronal - Sensory perception" "Cluster 7: Non-specific - Transcription" 5 Mitochondria "HPA048092: , HPA070386: " "unprognostic (1.26e-1)" "unprognostic (4.33e-2)" "unprognostic (8.74e-2)" "unprognostic (2.89e-1)" "unprognostic (1.03e-2)" "unprognostic (6.02e-3)" "unprognostic (2.83e-1)" "unprognostic (1.17e-1)" "unprognostic (1.18e-2)" "unprognostic (1.51e-1)" "validated prognostic favorable (8.02e-7)" "validated prognostic favorable (1.41e-5)" "unprognostic (3.68e-3)" "unprognostic (9.03e-2)" "unprognostic (1.31e-1)" "unprognostic (5.03e-2)" "unprognostic (1.46e-2)" "unprognostic (1.89e-1)" "unprognostic (5.51e-2)" "unprognostic (4.22e-3)" "unprognostic (2.74e-2)" "unprognostic (2.66e-1)" "unprognostic (4.40e-3)" "unprognostic (3.81e-1)" "unprognostic (1.44e-1)" "unprognostic (2.20e-2)" "unprognostic (2.31e-2)" "unprognostic (6.46e-2)" "unprognostic (1.00e-1)" "unprognostic (4.73e-2)" "unprognostic (8.42e-2)" PDRG1 "C20orf126, dJ310O13.3" ENSG00000088356 "P53 and DNA damage regulated 1" Q9NUG6 20 31944337-31952046 "Essential proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 65.1;Late primary spermatocytes: 92.9;Oocytes: 78.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047084, HPA063542" Approved Approved "Actin filaments" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 83 "Actin filaments" "HPA047084: , HPA063542: " "unprognostic (8.62e-3)" "unprognostic (5.11e-2)" "unprognostic (2.28e-1)" "unprognostic (3.89e-1)" "unprognostic (7.76e-2)" "unprognostic (2.14e-1)" "unprognostic (1.82e-1)" "unprognostic (2.96e-1)" "unprognostic (7.52e-2)" "unprognostic (2.86e-2)" "potential prognostic favorable (1.45e-4)" "unprognostic (1.68e-1)" "unprognostic (3.45e-1)" "validated prognostic unfavorable (1.52e-7)" "validated prognostic unfavorable (2.71e-5)" "unprognostic (7.70e-2)" "unprognostic (1.80e-2)" "unprognostic (1.54e-1)" "unprognostic (4.64e-2)" "unprognostic (2.62e-2)" "unprognostic (1.78e-1)" "unprognostic (9.69e-2)" "unprognostic (1.35e-1)" "unprognostic (2.30e-2)" "unprognostic (6.12e-2)" "unprognostic (1.04e-1)" "unprognostic (1.70e-1)" "unprognostic (2.25e-1)" "unprognostic (3.27e-1)" "unprognostic (3.77e-2)" "unprognostic (9.13e-2)" PDS5A "KIAA0648, PIG54, SCC-112" ENSG00000121892 "PDS5 cohesin associated factor A" Q29RF7 4 39822863-39977956 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036661, HPA036662" Enhanced Enhanced Nucleoplasm NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 53 Nucleoplasm "HPA036661: , HPA036662: " "unprognostic (2.05e-2)" "unprognostic (4.31e-2)" "unprognostic (1.04e-1)" "unprognostic (7.90e-2)" "unprognostic (4.87e-3)" "unprognostic (5.93e-2)" "unprognostic (1.15e-1)" "unprognostic (1.29e-1)" "unprognostic (9.60e-3)" "potential prognostic unfavorable (6.53e-4)" "potential prognostic favorable (1.40e-4)" "unprognostic (5.70e-3)" "unprognostic (1.77e-1)" "unprognostic (1.38e-2)" "unprognostic (7.61e-2)" "unprognostic (2.85e-2)" "unprognostic (2.76e-2)" "unprognostic (4.49e-2)" "unprognostic (8.93e-2)" "unprognostic (1.56e-1)" "unprognostic (2.46e-1)" "unprognostic (9.64e-3)" "unprognostic (4.47e-3)" "unprognostic (6.09e-2)" "unprognostic (2.90e-2)" "unprognostic (6.86e-2)" "unprognostic (2.81e-2)" "unprognostic (2.58e-1)" "unprognostic (1.06e-1)" "unprognostic (1.82e-1)" "unprognostic (1.33e-1)" PDS5B "APRIN, AS3, CG008, FLJ23236, KIAA0979" ENSG00000083642 "PDS5 cohesin associated factor B" Q9NTI5 13 32586452-32778019 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039513, HPA040015" Supported Enhanced Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 61: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 38 Nucleoplasm "HPA039513: , HPA040015: " "unprognostic (9.32e-2)" "unprognostic (3.85e-2)" "unprognostic (1.13e-2)" "unprognostic (1.90e-3)" "unprognostic (2.53e-1)" "unprognostic (2.50e-2)" "unprognostic (2.34e-1)" "unprognostic (6.88e-2)" "unprognostic (2.46e-1)" "unprognostic (8.40e-2)" "validated prognostic favorable (2.53e-5)" "validated prognostic favorable (3.06e-4)" "unprognostic (2.87e-1)" "unprognostic (4.66e-2)" "unprognostic (1.56e-2)" "unprognostic (3.84e-2)" "unprognostic (2.43e-1)" "unprognostic (8.98e-2)" "unprognostic (3.31e-1)" "unprognostic (1.43e-2)" "unprognostic (9.69e-2)" "unprognostic (6.68e-2)" "unprognostic (1.01e-2)" "unprognostic (1.03e-1)" "unprognostic (5.23e-2)" "unprognostic (4.93e-2)" "unprognostic (7.00e-2)" "unprognostic (4.12e-2)" "unprognostic (5.07e-1)" "unprognostic (3.09e-1)" "unprognostic (1.04e-1)" PDSS1 "COQ1, COQ1A, TPRT, TPT" ENSG00000148459 "Decaprenyl diphosphate synthase subunit 1" Q5T2R2 10 26697701-26746798 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Isoprene biosynthesis, Lipid metabolism, Ubiquinone biosynthesis" Transferase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 18.0" "Cell type enhanced" "Detected in many" "Monocyte progenitors: 74.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038032, HPA042741" Uncertain Approved Cytosol NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 77: Intestine - Digestion" "Cluster 2: Neurons - Nucleosome" "Cluster 52: Non-specific - Mitochondria" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 1 Cytosol "HPA038032: , HPA042741: " "unprognostic (1.20e-3)" "unprognostic (1.08e-2)" "unprognostic (2.39e-1)" "unprognostic (3.48e-2)" "potential prognostic favorable (5.60e-4)" "unprognostic (1.23e-1)" "unprognostic (9.44e-2)" "potential prognostic favorable (7.10e-6)" "unprognostic (2.99e-3)" "unprognostic (1.58e-1)" "potential prognostic favorable (7.71e-4)" "unprognostic (1.25e-1)" "unprognostic (1.15e-1)" "validated prognostic unfavorable (7.04e-6)" "validated prognostic unfavorable (6.33e-5)" "potential prognostic unfavorable (1.40e-5)" "unprognostic (6.34e-2)" "unprognostic (3.25e-1)" "unprognostic (5.06e-2)" "unprognostic (1.43e-1)" "unprognostic (1.29e-1)" "unprognostic (7.92e-2)" "unprognostic (1.38e-2)" "unprognostic (3.81e-2)" "unprognostic (1.89e-1)" "unprognostic (1.24e-2)" "unprognostic (2.03e-1)" "unprognostic (5.66e-3)" "unprognostic (1.39e-1)" "unprognostic (5.24e-2)" "unprognostic (4.37e-3)" PDSS2 "bA59I9.3, C6orf210, COQ1B" ENSG00000164494 "Decaprenyl diphosphate synthase subunit 2" Q86YH6 6 107152562-107459564 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Isoprene biosynthesis, Lipid metabolism, Ubiquinone biosynthesis" Transferase "Cancer-related genes, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029685, HPA029686" Approved Supported Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 76: Non-specific - Metabolism" "Cluster 55: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 1 Cytosol "HPA029685: , HPA029686: " "unprognostic (6.05e-2)" "validated prognostic unfavorable (4.97e-5)" "validated prognostic unfavorable (3.29e-6)" "unprognostic (2.45e-2)" "unprognostic (2.05e-2)" "potential prognostic favorable (3.45e-4)" "unprognostic (3.72e-1)" "unprognostic (1.61e-1)" "unprognostic (1.09e-1)" "unprognostic (7.52e-3)" "validated prognostic favorable (6.86e-7)" "validated prognostic favorable (6.76e-5)" "potential prognostic favorable (4.09e-4)" "unprognostic (1.20e-1)" "unprognostic (7.74e-2)" "unprognostic (2.15e-1)" "unprognostic (2.71e-1)" "unprognostic (1.21e-1)" "unprognostic (3.72e-1)" "unprognostic (1.52e-1)" "unprognostic (5.97e-2)" "unprognostic (1.65e-1)" "unprognostic (1.19e-1)" "unprognostic (1.70e-1)" "potential prognostic favorable (1.77e-5)" "unprognostic (1.32e-1)" "unprognostic (8.54e-2)" "unprognostic (2.79e-1)" "unprognostic (1.07e-1)" "unprognostic (9.16e-2)" "unprognostic (1.49e-1)" PDX1 "GSF, IDX-1, IPF1, IUF-1, MODY4, PDX-1, STF-1" ENSG00000139515 "Pancreatic and duodenal homeobox 1" P52945 13 27920000-27926313 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 39.4;pancreas: 12.2" "Cell type enhanced" "Detected in some" "Cholangiocytes: 17.2;Foveolar cells: 5.7;Gastric chief cells: 3.3;Gastric progenitor cells: 10.3;Neuroendocrine cells: 10.6;Pancreatic acinar cells: 3.4;Pancreatic duct cells: 24.9;Pancreatic islet cells: 18.4" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Colon Adenocarcinoma (TCGA): 11.1;Pancreatic Adenocarcinoma (TCGA): 11.7;Rectum Adenocarcinoma (TCGA): 11.2;Stomach Adenocarcinoma (TCGA): 10.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 6.2;Gastric cancer: 6.1" "Colon - Colon enterocytes" "Not detected" "Not detected" "Not detected" "Not detected" "CAB025873, HPA059146" Enhanced Supported Nucleoplasm NA NA "Cluster 60: Stomach - Digestion" "Cluster 59: Leukemia - T-cell receptor" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 6 Nucleoplasm "CAB025873: , HPA059146: " "unprognostic (1.53e-1)" "unprognostic (5.56e-1)" "unprognostic (3.57e-1)" "unprognostic (3.22e-2)" "unprognostic (4.31e-2)" "unprognostic (6.85e-2)" "unprognostic (1.52e-2)" "unprognostic (1.03e-1)" "unprognostic (3.38e-1)" "unprognostic (5.73e-2)" "unprognostic (9.86e-2)" "unprognostic (1.38e-1)" PDXDC1 KIAA0251 ENSG00000179889 "Pyridoxal dependent decarboxylase domain containing 1" Q6P996 16 14974591-15139339 "Predicted intracellular proteins" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 135.3;Distal convoluted tubule cells: 150.5;Early spermatids: 209.7;Late spermatids: 360.6;Loop of henle epithelial cells: 168.2;Papillary tip epithelial cells: 184.6;Podocytes: 194.9;Proximal tubule cells: 162.0;Renal collecting duct intercalated cells: 163.6;Renal collecting duct principal cells: 154.7;Renal connecting tubule cells: 156.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047369, HPA049121, HPA051484" Approved Enhanced "Golgi apparatus,Vesicles" NA NA 17000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 21: Testis - Mixed function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 54: Non-specific - Transcription" "Cluster 102: Non-specific - Mixed function" 36 "Golgi apparatus, Vesicles" "HPA047369: , HPA049121: , HPA051484: " "unprognostic (1.90e-3)" "unprognostic (8.82e-2)" "unprognostic (2.82e-2)" "unprognostic (1.65e-2)" "unprognostic (1.82e-1)" "unprognostic (1.21e-1)" "unprognostic (5.57e-2)" "unprognostic (1.76e-2)" "unprognostic (2.94e-1)" "unprognostic (4.35e-1)" "potential prognostic favorable (1.27e-4)" "unprognostic (2.59e-3)" "unprognostic (2.61e-1)" "unprognostic (1.56e-1)" "unprognostic (2.89e-2)" "unprognostic (1.19e-2)" "unprognostic (2.90e-1)" "unprognostic (6.14e-2)" "unprognostic (1.05e-3)" "unprognostic (3.47e-3)" "unprognostic (8.91e-3)" "unprognostic (1.42e-1)" "unprognostic (4.00e-1)" "unprognostic (2.58e-1)" "unprognostic (9.94e-3)" "unprognostic (2.69e-3)" "unprognostic (2.10e-1)" "unprognostic (2.47e-1)" "unprognostic (1.45e-1)" "unprognostic (7.79e-2)" "unprognostic (1.62e-1)" PDXK "C21orf124, C21orf97, FLJ21324, FLJ31940, MGC15873, PKH, PNK, PRED79" ENSG00000160209 "Pyridoxal kinase" O00764 21 43719094-43762307 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Charcot-Marie-Tooth disease, Disease variant, FDA approved drug targets, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 73.0" "Cell type enhanced" "Detected in many" "Early spermatids: 1661.7;Late primary spermatocytes: 2136.5;Late spermatids: 6953.5" "Cell type enhanced" "Detected in all" "endothelial cell: 381.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030196, HPA030197, HPA030198, CAB033918" Enhanced Enhanced Nucleoplasm NA NA 490000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 36: Brain & Liver - Signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 1 Nucleoplasm "CAB033918: , HPA030196: , HPA030197: , HPA030198: " "unprognostic (1.16e-1)" "unprognostic (4.38e-3)" "unprognostic (3.55e-2)" "unprognostic (4.41e-2)" "unprognostic (4.52e-2)" "unprognostic (2.90e-3)" "unprognostic (1.32e-1)" "unprognostic (9.40e-2)" "unprognostic (1.22e-2)" "unprognostic (1.72e-1)" "unprognostic (2.60e-1)" "unprognostic (2.31e-1)" "unprognostic (2.13e-2)" "unprognostic (4.74e-3)" "unprognostic (6.55e-3)" "unprognostic (1.56e-2)" "unprognostic (1.07e-1)" "unprognostic (1.07e-1)" "unprognostic (1.19e-1)" "unprognostic (2.00e-2)" "unprognostic (3.62e-3)" "unprognostic (1.95e-1)" "unprognostic (1.37e-2)" "unprognostic (3.68e-1)" "unprognostic (2.26e-2)" "unprognostic (1.28e-1)" "unprognostic (1.68e-1)" "unprognostic (4.55e-3)" "unprognostic (2.08e-1)" "potential prognostic unfavorable (9.37e-4)" "unprognostic (2.55e-1)" PDXP "CIN, dJ37E16.5, FLJ32703" ENSG00000241360 "Pyridoxal phosphatase" Q96GD0 22 37658723-37666932 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "brain: 257.9;liver: 72.4" "Group enriched" "Detected in some" 4 "Brain excitatory neurons: 35.4;Brain inhibitory neurons: 36.9;Other brain neurons: 50.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 8 "plasmacytoid DC: 11.6" "Lineage enriched" "Detected in many" 8 "dendritic cells: 11.6" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000531 Approved NA NA 140000 "Cluster 29: Non-specific - Unknown function" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 98: Neurons - Neurotransmission & signaling" 1 "HPA000531: " "unprognostic (2.39e-2)" "potential prognostic unfavorable (1.84e-4)" "unprognostic (1.45e-2)" "unprognostic (1.91e-2)" "unprognostic (1.31e-1)" "unprognostic (3.11e-2)" "unprognostic (1.47e-1)" "unprognostic (3.62e-3)" "unprognostic (1.07e-1)" "unprognostic (1.77e-2)" "potential prognostic favorable (8.56e-4)" "unprognostic (8.42e-2)" "unprognostic (3.14e-3)" "unprognostic (7.48e-2)" "unprognostic (1.52e-1)" "unprognostic (3.36e-1)" "unprognostic (2.17e-1)" "unprognostic (2.71e-3)" "unprognostic (5.69e-3)" "unprognostic (1.96e-2)" "unprognostic (5.06e-3)" "unprognostic (1.26e-3)" "unprognostic (1.08e-2)" "unprognostic (9.22e-2)" "unprognostic (4.26e-1)" "unprognostic (7.75e-2)" "unprognostic (3.97e-2)" "unprognostic (1.29e-1)" "unprognostic (3.90e-2)" "unprognostic (1.04e-1)" "unprognostic (3.32e-2)" PDYN "ADCA, PENKB, SCA23" ENSG00000101327 Prodynorphin P01213 20 1978757-1994285 "Disease related genes, Human disease related genes, Potential drug targets, Predicted secreted proteins, Transporters" "Endorphin, Neuropeptide, Neurotransmitter, Opioid peptide" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "brain: 125.1" "Group enriched" "Detected in some" 5 "Early spermatids: 49.0;Late spermatids: 178.1" "Cell type enhanced" "Detected in many" "eccentric medium spiny neuron: 39.2;hippocampal dentate gyrus: 25.4;medium spiny neuron: 25.0" "Group enriched" "Detected in some" 20 "Glioblastoma Multiforme (TCGA): 5.2;Ovary Serous Cystadenocarcinoma (TCGA): 2.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 12 "Bone cancer: 3.9" "Pituitary gland - Gonadotropes, Testis - Early spermatids, Testis - Late spermatids" "Group enriched" "Detected in many" 4 "basal ganglia: 152.2;hypothalamus: 60.7" "Region enhanced" "Detected in many" "basal ganglia: 173.9" "HPA053342, CAB079777" Enhanced Supported "Secreted in brain" Neuropeptide NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 29: Forebrain - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 4 "CAB079777: , HPA053342: " "unprognostic (1.39e-1)" "unprognostic (5.97e-2)" "unprognostic (8.98e-2)" "unprognostic (1.82e-1)" PDZD11 PDZK11 ENSG00000120509 "PDZ domain containing 11" Q5EBL8 X 70281118-70290514 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 104.5;Esophageal apical cells: 186.1;Esophageal basal cells: 97.5;Esophageal suprabasal cells: 141.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin), Spleen - Fibroblasts_1, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003972 Approved "Intracellular and membrane" "No annotated function" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 73: Brain - Neuronal signaling" "Cluster 21: Non-specific - Metabolism" "Cluster 36: Non-specific - mRNA processing" "Cluster 85: Squamous epithelial cells - Keratinization" 15 "HPA003972: " "unprognostic (5.86e-2)" "potential prognostic unfavorable (2.53e-4)" "unprognostic (2.23e-3)" "unprognostic (2.28e-3)" "unprognostic (4.18e-1)" "unprognostic (4.79e-2)" "unprognostic (6.53e-2)" "unprognostic (2.70e-2)" "potential prognostic unfavorable (6.84e-4)" "unprognostic (2.64e-3)" "unprognostic (1.82e-2)" "potential prognostic unfavorable (2.58e-4)" "unprognostic (2.19e-2)" "unprognostic (3.80e-3)" "potential prognostic unfavorable (3.00e-4)" "unprognostic (4.16e-3)" "unprognostic (3.26e-3)" "unprognostic (1.20e-1)" "unprognostic (8.26e-2)" "unprognostic (4.28e-2)" "unprognostic (2.56e-1)" "unprognostic (6.70e-3)" "unprognostic (9.39e-2)" "unprognostic (1.38e-1)" "unprognostic (2.06e-1)" "unprognostic (1.33e-1)" "unprognostic (1.74e-2)" "unprognostic (3.69e-1)" "unprognostic (5.66e-2)" "unprognostic (1.26e-1)" "unprognostic (5.06e-3)" PDZD2 "KIAA0300, PDZK3" ENSG00000133401 "PDZ domain containing 2" O15018 5 31639131-32110932 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 17.6" "Cell type enhanced" "Detected in many" "Adipocytes: 797.9;Cardiomyocytes: 875.8;Choroid plexus epithelial cells: 2846.4;Cone photoreceptor cells: 772.2;Oligodendrocyte progenitor cells: 1244.7;Proximal tubule cells: 1410.4;Rod photoreceptor cells: 745.2" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 2518.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 1" "Low region specificity" "Detected in all" "CAB020784, HPA036503, HPA036504, HPA064387, HPA076072" Uncertain Supported "Plasma membrane,Cytosol" "Intracellular and membrane" "Cell adhesion" NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 2 "Plasma membrane, Cytosol" "CAB020784: , HPA036503: , HPA036504: , HPA064387: , HPA076072: " "unprognostic (1.13e-1)" "unprognostic (1.21e-1)" "unprognostic (1.28e-2)" "unprognostic (3.32e-2)" "unprognostic (9.98e-2)" "unprognostic (2.59e-3)" "unprognostic (4.70e-3)" "unprognostic (7.44e-3)" "potential prognostic favorable (2.26e-8)" "unprognostic (3.60e-3)" "unprognostic (1.33e-2)" "unprognostic (3.61e-2)" "unprognostic (1.28e-2)" "unprognostic (3.54e-1)" "unprognostic (8.11e-2)" "unprognostic (1.16e-2)" "unprognostic (3.25e-1)" "unprognostic (3.42e-2)" "unprognostic (1.06e-1)" "unprognostic (2.07e-2)" "unprognostic (3.42e-2)" PDZD3 "FLJ22756, IKEPP, NHERF4, PDZK2" ENSG00000172367 "PDZ domain containing 3" Q86UT5 11 119185457-119190223 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "intestine: 18.2;kidney: 17.8" "Cell type enhanced" "Detected in some" "Colonocytes: 108.6;Enteric stem cells: 25.7;Enteric transient amplifying cells: 26.8;Enterocytes: 103.8;Foveolar cells: 39.4;Mesothelial cells: 13.8;Paneth cells: 19.3;Proximal tubule cells: 77.9" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney Renal Papillary Cell Carcinoma (TCGA): 6.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Pancreas - Ductal cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in single" HPA077887 Enhanced NA NA "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 6 "HPA077887: " "unprognostic (7.13e-2)" "unprognostic (1.54e-1)" "potential prognostic favorable (1.61e-4)" "unprognostic (3.24e-2)" "unprognostic (2.80e-2)" "unprognostic (4.54e-2)" "unprognostic (3.08e-1)" "unprognostic (1.74e-3)" "unprognostic (4.65e-2)" PDZD4 "FLJ34125, KIAA1444, LNX5, LU1, PDZK4, PDZRN4L" ENSG00000067840 "PDZ domain containing 4" Q76G19 X 153802166-153830565 "Cancer-related genes, Metabolic proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 269.0" "Cell type enhanced" "Detected in many" "Astrocytes: 17.5;Brain excitatory neurons: 24.7;Brain inhibitory neurons: 17.2;Choroid plexus epithelial cells: 29.6;Corticotrophs: 20.5;Ependymal cells: 42.9;Fallopian tube ciliated cells: 14.2;Hepatic stellate cells: 19.4;Lactotrophs: 20.0;NK-cells: 20.4;Other brain neurons: 14.9;Retinal amacrine cells: 18.1;Retinal bipolar cells: 13.9;Rod photoreceptor cells: 14.9;Schwann cells: 13.3" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Glioblastoma Multiforme (TCGA): 37.5;Testicular Germ Cell Tumor (TCGA): 17.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "Neuroblastoma: 46.8" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal medulla cells, Breast - Breast myoepithelial cells, Colon - Enteric glia cells, Minor Salivary Gland - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003878 Enhanced NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" "HPA003878: " "unprognostic (4.46e-3)" "unprognostic (8.69e-3)" "unprognostic (1.68e-1)" "potential prognostic favorable (6.87e-5)" "unprognostic (1.91e-1)" "unprognostic (4.46e-3)" "unprognostic (2.22e-2)" "unprognostic (2.76e-2)" "unprognostic (1.11e-1)" "potential prognostic unfavorable (6.73e-4)" "potential prognostic favorable (1.14e-4)" "unprognostic (1.13e-1)" "unprognostic (6.66e-3)" "unprognostic (4.69e-2)" "unprognostic (7.28e-2)" "unprognostic (1.87e-1)" "potential prognostic favorable (1.09e-4)" "unprognostic (4.88e-2)" "unprognostic (9.20e-2)" "unprognostic (1.31e-2)" "unprognostic (1.64e-2)" "unprognostic (2.88e-1)" "unprognostic (8.77e-2)" PDZD7 "bA108L7.8, DFNB57, FLJ23209, PDZK7" ENSG00000186862 "PDZ domain containing 7" Q9H5P4 10 101007679-101032295 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Deafness, Disease variant, Non-syndromic deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 21.2;intestine: 18.8;pituitary gland: 7.1" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 29.3;Brain inhibitory neurons: 28.0;Enterocytes: 88.4;Gonadotrophs: 33.2;Other brain neurons: 16.5;Podocytes: 16.8;Retinal amacrine cells: 26.9;Retinal ganglion cells: 38.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA074542 Approved "Nucleoplasm,Primary cilium,Basal body" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 27: Cerebellum - Synaptic function" "Cluster 37: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 1: Enterocytes - Absorption and Digestion" 1 "Nucleoplasm, Primary cilium" "Basal body" "HPA074542: " "unprognostic (1.37e-2)" "unprognostic (2.17e-2)" "unprognostic (1.72e-1)" "unprognostic (3.59e-2)" "unprognostic (3.40e-3)" "unprognostic (4.75e-2)" "unprognostic (7.53e-2)" "unprognostic (7.70e-2)" "unprognostic (1.18e-3)" "unprognostic (2.42e-2)" "unprognostic (1.30e-1)" "unprognostic (2.26e-1)" "unprognostic (1.24e-3)" "unprognostic (5.41e-2)" "unprognostic (6.23e-2)" "unprognostic (4.86e-2)" "unprognostic (2.62e-2)" "unprognostic (4.62e-1)" "potential prognostic unfavorable (4.84e-4)" "unprognostic (1.98e-2)" "potential prognostic favorable (1.37e-4)" "unprognostic (2.85e-1)" "unprognostic (7.02e-2)" "unprognostic (2.14e-1)" "unprognostic (7.31e-3)" "unprognostic (6.55e-2)" PDZD8 "bA129M16.2, FLJ34427, PDZK8" ENSG00000165650 "PDZ domain containing 8" Q8NEN9 10 117277274-117375440 "Predicted intracellular proteins, Transporters" "Host-virus interaction, Lipid transport, Transport" "Autism spectrum disorder, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 68.9" "Cell type enhanced" "Detected in all" "Erythrocyte progenitors: 438.8;Late spermatids: 882.0;Megakaryocyte progenitors: 487.3;Megakaryocyte-Erythroid progenitors: 1099.2;Neutrophil progenitors: 1267.1;Neutrophils: 671.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015716, HPA051610" Uncertain Approved "Nucleoli fibrillar center,Plasma membrane" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 45: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 52 "Nucleoli fibrillar center" "Plasma membrane" "HPA015716: , HPA051610: " "unprognostic (1.57e-1)" "unprognostic (3.89e-2)" "unprognostic (1.59e-1)" "unprognostic (6.30e-2)" "unprognostic (1.91e-1)" "unprognostic (1.14e-1)" "unprognostic (4.14e-2)" "unprognostic (2.95e-3)" "unprognostic (2.06e-2)" "unprognostic (8.65e-2)" "potential prognostic favorable (9.73e-6)" "unprognostic (1.40e-2)" "unprognostic (1.11e-2)" "unprognostic (3.15e-1)" "unprognostic (7.03e-2)" "unprognostic (4.64e-2)" "unprognostic (2.54e-1)" "unprognostic (2.64e-1)" "unprognostic (3.88e-1)" "unprognostic (8.62e-2)" "potential prognostic unfavorable (7.32e-4)" "unprognostic (1.66e-3)" "unprognostic (5.01e-2)" "unprognostic (4.00e-2)" "unprognostic (4.97e-3)" "unprognostic (4.69e-2)" "unprognostic (3.14e-1)" "unprognostic (9.99e-3)" "unprognostic (4.59e-2)" "unprognostic (1.56e-2)" "unprognostic (1.93e-1)" PDZD9 "C16orf65, MGC50721" ENSG00000155714 "PDZ domain containing 9" Q8IXQ8 16 21983865-22001116 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "testis: 10.4" "Cell type enhanced" "Detected in some" "Astrocytes: 2.7;Bergmann glia: 4.0;Brain excitatory neurons: 4.8;Brain inhibitory neurons: 4.5;Early spermatids: 3.3;Late primary spermatocytes: 5.5;Late spermatids: 10.6;Loop of henle epithelial cells: 3.1;Oligodendrocyte progenitor cells: 2.7;Oligodendrocytes: 1.5;Other brain neurons: 3.2;Renal collecting duct principal cells: 1.9" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA042457 Approved "Nuclear speckles,Plasma membrane,Primary cilium,Cytosol" NA NA "Cluster 67: Testis - Mixed function" "Cluster 98: Neurons - Neurotransmission & signaling" "Plasma membrane, Cytosol" "Nuclear speckles, Primary cilium" "HPA042457: " PDZK1 "NHERF3, PDZD1" ENSG00000174827 "PDZ domain containing 1" Q5T2W1 1 145670852-145708148 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "kidney: 556.3" "Cell type enhanced" "Detected in many" "Cholangiocytes: 84.8;Enterocytes: 325.2;Epididymal efferent duct absorptive cells: 102.4;Hepatocytes: 63.3;Loop of henle epithelial cells: 50.1;Proximal tubule cells: 390.5" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 22.4;upper rhombic lip: 24.4" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 180.3;Kidney Renal Papillary Cell Carcinoma (TCGA): 190.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "NK-cell: 4.2" "Lineage enriched" "Detected in single" 5 "NK-cells: 4.2" "Cancer enhanced" "Detected in many" "Kidney cancer: 108.6" "Breast - Breast glandular cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Skin - Sebaceous gland cells, Stomach - Gastric enteroendocrine cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA005755, HPA006155, CAB008971" Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA 66000 "Cluster 14: Non-specific - Unknown function" "Cluster 72: Kidney - Transmembrane transport" "Cluster 35: Non-specific - DNA binding" "Cluster 27: Breast cancer - Unknown function" "Cluster 88: Proximal tubular cells - Transmembrane transport" 23 "Nucleoplasm, Vesicles" Cytosol "CAB008971: , HPA005755: , HPA006155: " "unprognostic (3.66e-2)" "unprognostic (9.21e-3)" "unprognostic (1.07e-1)" "unprognostic (5.44e-2)" "unprognostic (9.97e-2)" "unprognostic (1.55e-1)" "unprognostic (9.90e-2)" "unprognostic (7.57e-3)" "unprognostic (3.34e-1)" "unprognostic (2.17e-1)" "validated prognostic favorable (1.30e-9)" "validated prognostic favorable (8.22e-4)" "unprognostic (1.61e-2)" "unprognostic (2.32e-1)" "unprognostic (2.76e-2)" "unprognostic (2.17e-1)" "unprognostic (1.98e-1)" "unprognostic (3.53e-2)" "unprognostic (1.28e-1)" "unprognostic (3.43e-2)" "unprognostic (1.10e-1)" "unprognostic (1.75e-1)" "unprognostic (2.85e-1)" "unprognostic (1.84e-1)" PDZK1IP1 "DD96, MAP17, SPAP" ENSG00000162366 "PDZK1 interacting protein 1" Q13113 1 47183582-47191044 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "kidney: 1034.4" "Cell type enhanced" "Detected in many" "Breast lactating cells: 532.2;Cholangiocytes: 236.5;Endometrial secretory cells: 501.1;Epididymal efferent duct absorptive cells: 419.8;Esophageal apical cells: 2333.3;Esophageal suprabasal cells: 628.0;Gastric progenitor cells: 293.5;Salivary acinar cells: 267.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Kidney Renal Papillary Cell Carcinoma (TCGA): 1568.5" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "neutrophil: 6.6" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Kidney cancer: 497.6" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Kidney - Proximal tubular cells, Minor Salivary Gland - Minor salivary glandular cells, Spleen - Erythrocytes" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA014907 Enhanced Approved "Nuclear speckles,Cytosol" NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 72: Kidney - Transmembrane transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 15: Kidney cancer - Membrane components" "Cluster 84: Apical squamous epithelium - Cornification" 73 Cytosol "Nuclear speckles" "HPA014907: " "unprognostic (1.82e-1)" "unprognostic (2.08e-1)" "unprognostic (5.51e-2)" "unprognostic (7.23e-3)" "unprognostic (1.63e-1)" "unprognostic (3.77e-1)" "potential prognostic unfavorable (4.79e-5)" "unprognostic (7.93e-2)" "unprognostic (2.01e-2)" "unprognostic (4.60e-2)" "unprognostic (7.44e-3)" "unprognostic (1.45e-1)" "unprognostic (1.31e-2)" "unprognostic (1.58e-1)" "unprognostic (1.06e-1)" "unprognostic (4.45e-2)" "unprognostic (5.69e-2)" "unprognostic (1.24e-2)" "unprognostic (5.07e-3)" "unprognostic (1.85e-1)" "unprognostic (3.75e-2)" "potential prognostic unfavorable (2.93e-4)" "unprognostic (1.24e-2)" "unprognostic (8.26e-2)" "unprognostic (1.31e-1)" "unprognostic (9.22e-2)" "unprognostic (2.04e-1)" "unprognostic (9.41e-2)" "unprognostic (2.11e-1)" "unprognostic (2.49e-3)" "unprognostic (1.39e-1)" PDZRN3 "KIAA1095, LNX3, SEMACAP3, SEMCAP3" ENSG00000121440 "PDZ domain containing ring finger 3" Q9UPQ7 3 73382431-73624941 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 1163.3;Adrenal cortex cells: 882.7;Cardiomyocytes: 1323.3;Choroid plexus epithelial cells: 3031.7;Endometrial stromal cells: 836.7;Myonuclei: 624.5;Prostatic glandular cells: 586.7" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 2398.4;fibroblast: 2333.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 19 "plasmacytoid DC: 1.9" "Lineage enriched" "Detected in single" 19 "dendritic cells: 1.9" "Cancer enhanced" "Detected in many" "Neuroblastoma: 23.9;skin cancer: 17.9" "Adrenal gland - Adrenal cortex cells, Breast - Fibroblasts, Heart muscle - Cardiomyocytes, Liver - Hepatic stellate cells, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Skin - Outer root sheath cells, Spleen - Fibroblasts_1" "Group enriched" "Detected in many" 4 "amygdala: 15.2;basal ganglia: 8.1;cerebral cortex: 19.5;hippocampal formation: 16.1;white matter: 7.2" "Low region specificity" "Detected in many" "HPA038822, HPA061420" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 9 Cytosol Nucleoplasm "HPA038822: , HPA061420: " "unprognostic (5.34e-2)" "unprognostic (2.29e-2)" "unprognostic (6.29e-2)" "unprognostic (7.46e-3)" "unprognostic (1.31e-1)" "unprognostic (1.34e-1)" "unprognostic (2.83e-1)" "unprognostic (1.44e-1)" "unprognostic (4.28e-2)" "unprognostic (5.31e-2)" "validated prognostic favorable (5.28e-8)" "validated prognostic favorable (6.79e-4)" "unprognostic (1.45e-3)" "unprognostic (1.73e-1)" "unprognostic (8.40e-3)" "unprognostic (9.31e-2)" "unprognostic (4.83e-1)" "unprognostic (1.08e-2)" "potential prognostic unfavorable (6.84e-4)" "unprognostic (1.51e-3)" "unprognostic (3.44e-1)" "unprognostic (1.53e-1)" "unprognostic (4.52e-2)" "unprognostic (3.68e-1)" "unprognostic (2.04e-1)" "unprognostic (2.07e-2)" "unprognostic (1.77e-1)" "unprognostic (4.45e-2)" "unprognostic (2.45e-3)" PDZRN4 "DKFZp434B0417, FLJ33777, IMAGE5767589, LNX4" ENSG00000165966 "PDZ domain containing ring finger 4" Q6ZMN7 12 41188320-41574745 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 14.3;intestine: 14.6;seminal vesicle: 16.8" "Cell type enhanced" "Detected in many" "Bergmann glia: 615.3;Corticotrophs: 586.8;Fibro-adipogenic progenitors: 359.6;Fibroblasts: 398.1;Gonadotrophs: 281.5;Granulosa cells: 279.0;Lactotrophs: 366.2;Leydig cells: 913.7;Mesothelial cells: 349.2;Oligodendrocyte progenitor cells: 962.1;Peritubular myoid cells: 1469.3;Retinal bipolar cells: 415.4;Smooth muscle cells: 496.1;Vascular smooth muscle cells: 396.6" "Cell type enhanced" "Detected in all" "deep-layer corticothalamic and 6b: 1015.3;oligodendrocyte precursor cell: 1133.5" "Cancer enhanced" "Detected in some" "Kidney Chromophobe (TCGA): 5.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 1.3;ovarian cancer: 1.6" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Smooth muscle cells, Liver - Hepatic stellate cells, Prostate - Smooth muscle cells, Skin - Fibroblasts_2, Spleen - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA042101 Enhanced Approved Mitochondria NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 53: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 108: Fibroblasts - ECM organization" Mitochondria "HPA042101: " "unprognostic (1.97e-1)" "unprognostic (1.97e-1)" "unprognostic (1.76e-2)" "unprognostic (1.16e-1)" "unprognostic (3.53e-3)" "unprognostic (1.07e-1)" "unprognostic (1.48e-3)" "unprognostic (4.09e-2)" PEA15 "HMAT1, HUMMAT1H, MAT1, MAT1H, PEA-15, PED, PED-PEA15, PED/PEA15" ENSG00000162734 "Proliferation and apoptosis adaptor protein 15" Q15121 1 160205380-160215376 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "brain: 1945.8" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 544.1;Müller glia: 207.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 857.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "intermediate monocyte: 78.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Spleen - Fibroblasts_1, Testis - Sertoli cells, Thyroid gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028356, HPA070820" Enhanced Supported Nucleoplasm,Vesicles,Cytosol NA NA 140000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 27: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 11: Muller glia cells - Retinal homeostasis" 13 Cytosol "Nucleoplasm, Vesicles" "HPA028356: , HPA070820: " "unprognostic (1.95e-1)" "unprognostic (1.16e-1)" "unprognostic (3.38e-1)" "potential prognostic unfavorable (2.99e-4)" "unprognostic (7.92e-3)" "unprognostic (6.56e-2)" "unprognostic (9.09e-2)" "potential prognostic favorable (1.04e-4)" "unprognostic (5.03e-2)" "unprognostic (2.77e-3)" "unprognostic (1.41e-3)" "unprognostic (5.86e-3)" "potential prognostic unfavorable (8.10e-4)" "unprognostic (2.65e-3)" "unprognostic (2.29e-2)" "unprognostic (9.90e-2)" "potential prognostic unfavorable (3.57e-4)" "unprognostic (7.70e-2)" "unprognostic (1.43e-2)" "unprognostic (3.73e-1)" "unprognostic (1.20e-1)" "unprognostic (4.92e-2)" "unprognostic (1.67e-1)" "unprognostic (1.37e-1)" "unprognostic (3.50e-3)" "unprognostic (8.39e-3)" "unprognostic (2.06e-1)" "unprognostic (1.82e-2)" "unprognostic (1.05e-1)" "unprognostic (6.72e-2)" "unprognostic (2.23e-1)" PEAK1 "KIAA2002, sgk269" ENSG00000173517 "Pseudopodium enriched atypical kinase 1" Q9H792 15 77100656-77420144 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Lymphatic endothelial cells: 625.1;Oligodendrocyte progenitor cells: 707.8;Sertoli cells: 841.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 1.9" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Spleen - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012773, HPA026313, HPA026517" Approved Supported "Focal adhesion sites,Cytosol" NA NA "Cluster 66: Lymphoid tissue - Immune response" "Cluster 34: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 21 "Focal adhesion sites" Cytosol "HPA012773: , HPA026313: , HPA026517: " "potential prognostic favorable (3.92e-4)" "unprognostic (6.23e-2)" "unprognostic (2.85e-1)" "unprognostic (7.02e-2)" "potential prognostic unfavorable (2.17e-4)" "unprognostic (4.70e-2)" "unprognostic (6.55e-3)" "unprognostic (1.94e-1)" "unprognostic (9.85e-3)" "validated prognostic favorable (3.10e-5)" "validated prognostic favorable (3.03e-5)" "unprognostic (1.79e-1)" "unprognostic (7.11e-3)" "unprognostic (2.20e-1)" "unprognostic (6.51e-2)" "unprognostic (1.30e-1)" "unprognostic (1.18e-2)" "unprognostic (2.29e-1)" "unprognostic (1.44e-3)" "unprognostic (2.85e-2)" "unprognostic (1.01e-1)" "unprognostic (5.35e-2)" "unprognostic (1.38e-1)" "unprognostic (4.89e-2)" "unprognostic (2.95e-2)" "unprognostic (3.06e-2)" "unprognostic (5.00e-2)" "unprognostic (1.28e-1)" "unprognostic (2.01e-2)" "unprognostic (2.84e-1)" PEAK3 "C19orf35, FLJ45778" ENSG00000188305 "PEAK family member 3" Q6ZS72 19 2274631-2282175 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 2.2;lymphoid tissue: 3.9" "Cell type enhanced" "Detected in many" "B-cells: 12.1;Epicardial cells: 20.5;Medullary thymic epithelial cells: 9.6;Neutrophil progenitors: 19.8;Neutrophils: 50.1" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 2.1;endothelial cell: 2.0;leukocyte: 2.6;vascular associated smooth muscle cell: 2.0" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 40.4" "Lineage enriched" "Detected in many" 7 "granulocytes: 40.4" "Cancer enriched" "Detected in single" 5 "Leukemia: 1.0" "Adrenal gland - Macrophages, Colon - Macrophages, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Spleen - Neutrophils_2, Stomach - Macrophages, Thyroid gland - Macrophages" "Group enriched" "Detected in some" 5 "basal ganglia: 8.8;cerebellum: 4.2" HPA057806 Uncertain Uncertain Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 6 Cytosol "HPA057806: " "unprognostic (9.74e-2)" "unprognostic (3.84e-2)" "unprognostic (2.32e-1)" "unprognostic (6.98e-3)" PEAR1 "FLJ00193, JEDI, MEGF12" ENSG00000187800 "Platelet endothelial aggregation receptor 1" Q5VY43 1 156893698-156916429 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 4 "Platelets: 316.1" "Group enriched" "Detected in some" 39 "endothelial cell: 41.6;fibroblast: 45.2;pericyte: 113.4;vascular associated smooth muscle cell: 51.5" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 6.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "thyroid cancer: 9.4" "Adipose subcutaneous - Endothelial cells, Adrenal gland - Fibroblasts, Breast - Endothelial cells, Colon - Endothelial cells, Minor Salivary Gland - Endothelial cells, Pituitary gland - Fibroblasts, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035217 Approved Approved "Nucleoplasm,Cell Junctions,Centriolar satellite" NA NA 11000000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 47: Platelets - Hemostasis" 2 "Nucleoplasm, Cell Junctions, Centriolar satellite" "HPA035217: " "unprognostic (1.67e-1)" "unprognostic (2.16e-1)" "unprognostic (8.85e-2)" "unprognostic (7.79e-2)" "unprognostic (1.52e-1)" "unprognostic (5.63e-2)" "unprognostic (2.29e-1)" "validated prognostic favorable (5.88e-6)" "validated prognostic favorable (7.29e-4)" "potential prognostic favorable (9.65e-5)" "unprognostic (1.78e-2)" "unprognostic (7.15e-2)" "unprognostic (2.97e-2)" "unprognostic (1.90e-1)" "potential prognostic unfavorable (5.74e-4)" "unprognostic (9.18e-2)" "unprognostic (2.64e-1)" "unprognostic (2.16e-3)" "unprognostic (2.38e-2)" "unprognostic (4.22e-3)" PEBP1 "HCNP, PBP, PEBP, RKIP" ENSG00000089220 "Phosphatidylethanolamine binding protein 1" P30086 12 118136124-118145584 "Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 2060.5;liver: 1946.9" "Cell type enhanced" "Detected in all" "Enterocytes: 1927.6;Esophageal apical cells: 1687.5;Hepatocytes: 2597.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "HPA008819, CAB009906, CAB013493, HPA063904, CAB080063" Enhanced Approved "Plasma membrane,Cytosol" NA NA 28000000 "Cluster 18: Non-specific - Translation" "Cluster 76: Non-specific - Metabolism" "Cluster 27: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 20 "Plasma membrane, Cytosol" "CAB009906: , CAB013493: , CAB080063: , HPA008819: , HPA063904: " "unprognostic (3.04e-2)" "unprognostic (1.36e-2)" "unprognostic (1.34e-1)" "unprognostic (2.49e-1)" "unprognostic (3.94e-1)" "unprognostic (1.03e-1)" "unprognostic (7.00e-2)" "unprognostic (7.65e-2)" "unprognostic (5.43e-2)" "unprognostic (6.01e-2)" "potential prognostic favorable (9.06e-10)" "unprognostic (3.44e-3)" "potential prognostic favorable (1.31e-5)" "unprognostic (3.56e-2)" "unprognostic (5.38e-2)" "potential prognostic favorable (6.13e-4)" "unprognostic (1.03e-1)" "unprognostic (2.04e-1)" "unprognostic (1.07e-1)" "unprognostic (1.98e-1)" "unprognostic (7.99e-3)" "potential prognostic favorable (8.22e-4)" "unprognostic (4.75e-2)" "unprognostic (9.95e-2)" "unprognostic (1.83e-1)" "unprognostic (2.18e-2)" "unprognostic (7.45e-2)" "unprognostic (6.87e-2)" "unprognostic (8.62e-2)" "unprognostic (1.18e-2)" "unprognostic (2.48e-3)" PEBP4 "CORK1, hPEBP4, MGC22776" ENSG00000134020 "Phosphatidylethanolamine binding protein 4" Q96S96 8 22713251-23000000 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 361.1;skeletal muscle: 628.6;tongue: 542.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 302.1;Alveolar cells type 2: 857.4;Epididymal principal cells: 967.8;Late spermatids: 170.1;Müller glia: 268.8;Myonuclei: 1086.2;Prostatic glandular cells: 170.0;Transitional alveolar cells: 435.1" "Cell type enhanced" "Detected in all" "astrocyte: 97.3;ependymal cell: 82.2" "Group enriched" "Detected in many" 6 "Lung Adenocarcinoma (TCGA): 42.4;Prostate Adenocarcinoma (TCGA): 55.9;Thyroid Carcinoma (TCGA): 84.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "prostate cancer: 9.4" "Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Stomach - Chief cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA025064 Uncertain "Secreted in other tissues" "No annotated function" NA NA 39000000 "Cluster 20: Non-specific - DNA binding" "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 19: Astrocytes - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 5 "HPA025064: " "unprognostic (2.72e-3)" "unprognostic (5.26e-3)" "unprognostic (1.53e-1)" "unprognostic (2.75e-2)" "unprognostic (6.69e-2)" "potential prognostic favorable (1.78e-4)" "unprognostic (1.88e-3)" "unprognostic (1.20e-2)" "unprognostic (8.77e-2)" "unprognostic (3.30e-1)" "unprognostic (7.69e-3)" "unprognostic (2.86e-1)" "unprognostic (9.91e-2)" PECAM1 CD31 ENSG00000261371 "Platelet and endothelial cell adhesion molecule 1" P16284 17 64319415-64413776 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Phagocytosis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 427.4" "Cell type enhanced" "Detected in many" "Kupffer cells: 171.2;Lymphatic endothelial cells: 440.1;Macrophages: 152.3;Megakaryocyte progenitors: 170.0;Megakaryocytes: 160.7;Monocyte progenitors: 216.7;monocytes: 283.8;Neutrophils: 524.5;pDCs: 168.1;Plasma cells: 166.4;Platelets: 486.1;Vascular endothelial cells: 1148.4" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 140.9;endothelial cell: 446.3;leukocyte: 107.9" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 166.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 706.3" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in many" 5 "Leukemia: 41.9" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Lung - Endothelial cells, Minor Salivary Gland - Endothelial cells, Pancreas - Endothelial cells, Pituitary gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004690, HPA004871" Enhanced Approved "Nucleoli,Plasma membrane" NA NA 16000000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 66 "Nucleoli, Plasma membrane" "HPA004690: , HPA004871: " "unprognostic (1.07e-1)" "unprognostic (3.74e-1)" "unprognostic (1.71e-1)" "unprognostic (6.38e-2)" "unprognostic (5.71e-2)" "unprognostic (1.12e-1)" "unprognostic (2.42e-2)" "unprognostic (2.23e-2)" "unprognostic (1.01e-1)" "validated prognostic favorable (1.17e-10)" "validated prognostic favorable (6.17e-5)" "potential prognostic unfavorable (7.07e-4)" "unprognostic (2.02e-1)" "unprognostic (8.94e-2)" "unprognostic (1.09e-3)" "unprognostic (6.36e-2)" "unprognostic (5.17e-3)" "unprognostic (1.02e-1)" "unprognostic (3.52e-2)" "unprognostic (2.20e-1)" "unprognostic (1.32e-1)" "unprognostic (3.53e-2)" "unprognostic (1.57e-1)" "unprognostic (2.10e-1)" "unprognostic (2.35e-3)" "unprognostic (8.33e-3)" "unprognostic (1.06e-2)" "unprognostic (1.84e-1)" PECR "HSA250303, SDR29C1, TERP" ENSG00000115425 "Peroxisomal trans-2-enoyl-CoA reductase" Q9BY49 2 215996329-216082955 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 149.7" "Cell type enhanced" "Detected in many" "Adipocytes: 370.7;Hepatocytes: 135.3;Neutrophil progenitors: 116.9;Neutrophils: 97.3;Proximal tubule cells: 81.0;Renal collecting duct principal cells: 93.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 59.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Liver - Hepatocytes, Skin - Sebaceous gland cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021593, HPA022539" Enhanced Supported Peroxisomes NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 4 Peroxisomes "HPA021593: , HPA022539: " "unprognostic (2.63e-1)" "unprognostic (5.68e-2)" "unprognostic (1.20e-1)" "unprognostic (1.99e-1)" "unprognostic (8.59e-2)" "unprognostic (6.68e-2)" "unprognostic (1.59e-1)" "unprognostic (5.03e-2)" "unprognostic (6.41e-2)" "unprognostic (1.26e-2)" "potential prognostic favorable (4.58e-9)" "unprognostic (3.33e-2)" "unprognostic (1.50e-1)" "unprognostic (5.61e-3)" "potential prognostic favorable (7.28e-5)" "unprognostic (7.41e-2)" "unprognostic (1.33e-1)" "unprognostic (2.01e-1)" "unprognostic (4.63e-2)" "unprognostic (1.41e-1)" "unprognostic (8.92e-2)" "unprognostic (1.12e-3)" "unprognostic (4.93e-1)" "unprognostic (1.01e-2)" "unprognostic (1.72e-1)" "unprognostic (7.00e-2)" "unprognostic (4.54e-2)" "unprognostic (3.05e-2)" "unprognostic (4.28e-2)" "unprognostic (1.22e-1)" "unprognostic (3.73e-2)" PEDS1 "CarF, Kua, TMEM189" ENSG00000240849 "Plasmanylethanolamine desaturase 1" A5PLL7 20 50118254-50153734 "Enzymes, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in some" 4 "Late spermatids: 153.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059549 Approved Supported "Endoplasmic reticulum" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 62: Non-specific - Plasma proteins" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 4 "Endoplasmic reticulum" "HPA059549: " "unprognostic (1.51e-2)" "unprognostic (1.70e-3)" "unprognostic (2.74e-2)" "unprognostic (8.87e-2)" "unprognostic (5.63e-2)" "unprognostic (1.88e-2)" "unprognostic (2.02e-1)" "unprognostic (2.68e-2)" "unprognostic (2.48e-1)" "validated prognostic unfavorable (2.52e-7)" "validated prognostic unfavorable (3.74e-4)" "unprognostic (2.25e-2)" "potential prognostic unfavorable (4.97e-4)" "unprognostic (2.58e-2)" "unprognostic (1.15e-1)" "unprognostic (3.53e-2)" "unprognostic (9.71e-3)" "unprognostic (1.19e-1)" "unprognostic (1.64e-1)" "unprognostic (1.81e-2)" "unprognostic (3.66e-2)" "unprognostic (9.95e-2)" "unprognostic (1.50e-2)" "unprognostic (1.26e-1)" "unprognostic (1.16e-1)" "unprognostic (1.27e-1)" "unprognostic (3.15e-1)" "unprognostic (3.59e-2)" "unprognostic (2.30e-2)" PEDS1-UBE2V1 "CROC-1B, Kua-UEV, TMEM189-UBE2V1" ENSG00000124208 "PEDS1-UBE2V1 readthrough" 20 50081124-50153637 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 4 "Late spermatids: 23.0" "Cancer enhanced" "Detected in many" "Stomach Adenocarcinoma (TCGA): 21.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "HPA052535, HPA053186" Supported Nucleoplasm NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 62: Non-specific - Plasma proteins" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 2 Nucleoplasm "HPA052535: , HPA053186: " "unprognostic (2.58e-3)" "unprognostic (3.77e-2)" "unprognostic (1.28e-1)" "potential prognostic favorable (2.64e-4)" "unprognostic (8.05e-2)" "unprognostic (3.19e-2)" "unprognostic (3.01e-1)" "unprognostic (4.79e-1)" "potential prognostic favorable (2.70e-5)" "unprognostic (1.97e-1)" "unprognostic (4.14e-1)" "unprognostic (2.20e-1)" "unprognostic (7.87e-3)" "unprognostic (4.36e-1)" "unprognostic (2.33e-1)" "potential prognostic unfavorable (6.12e-4)" "unprognostic (5.65e-2)" "unprognostic (2.12e-1)" "unprognostic (5.02e-2)" "unprognostic (1.12e-2)" "unprognostic (2.05e-1)" "unprognostic (2.57e-1)" "unprognostic (5.35e-1)" PEF1 PEF1A ENSG00000162517 "Penta-EF-hand domain containing 1" Q9UBV8 1 31629866-31644896 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 186.0;Esophageal apical cells: 149.3;Late spermatids: 139.9;Migrating cytotrophoblasts: 181.0;Syncytiotrophoblasts: 209.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061608 Approved Nucleoplasm,Vesicles,Cytosol NA NA 710000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 74: Non-specific - Signal transduction" "Cluster 45: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 45 "Nucleoplasm, Vesicles" Cytosol "HPA061608: " "unprognostic (1.41e-2)" "unprognostic (5.61e-2)" "unprognostic (7.36e-2)" "unprognostic (9.33e-3)" "unprognostic (1.86e-1)" "unprognostic (1.62e-1)" "unprognostic (2.43e-1)" "unprognostic (3.35e-3)" "unprognostic (1.48e-1)" "unprognostic (1.45e-1)" "potential prognostic favorable (3.88e-6)" "unprognostic (6.06e-2)" "unprognostic (1.74e-3)" "validated prognostic unfavorable (2.77e-5)" "validated prognostic unfavorable (2.10e-4)" "unprognostic (2.39e-3)" "unprognostic (2.08e-1)" "unprognostic (1.45e-1)" "unprognostic (5.41e-2)" "unprognostic (1.23e-1)" "unprognostic (2.35e-1)" "unprognostic (1.30e-2)" "unprognostic (6.36e-2)" "unprognostic (3.53e-1)" "unprognostic (1.05e-2)" "unprognostic (3.25e-2)" "unprognostic (3.32e-1)" "unprognostic (1.04e-2)" "unprognostic (3.46e-2)" "unprognostic (4.00e-2)" "unprognostic (6.20e-2)" PEG10 "HB-1, KIAA1051, Mar2, Mart2, MEF3L, RGAG3, RTL2, SIRH1" ENSG00000242265 "Paternally expressed 10" Q86TG7 7 94656325-94669695 "Predicted intracellular proteins" "Apoptosis, Differentiation, Transport" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 162.5;placenta: 439.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 505.2;Corticotrophs: 1028.1;Cytotrophoblasts: 2584.1;Gonadotrophs: 933.2;Migrating cytotrophoblasts: 1309.9;Other brain neurons: 444.7;Pancreatic islet cells: 425.3;Syncytiotrophoblasts: 2986.8;Transitional alveolar cells: 537.7" "Cell type enhanced" "Detected in all" "eccentric medium spiny neuron: 216.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Testis - Sertoli cells" "Region enhanced" "Detected in all" "hypothalamus: 110.8" "Low region specificity" "Detected in all" "HPA021324, HPA029915, HPA051038" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 18: Liver cancer - Metabolism" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 32 Cytosol Nucleoplasm "HPA021324: , HPA029915: , HPA051038: " "unprognostic (8.25e-2)" "unprognostic (2.37e-2)" "unprognostic (1.65e-1)" "unprognostic (6.53e-2)" "unprognostic (8.68e-2)" "unprognostic (1.43e-1)" "unprognostic (2.73e-1)" "unprognostic (5.74e-2)" "unprognostic (8.07e-3)" "unprognostic (7.83e-3)" "potential prognostic favorable (6.80e-4)" "unprognostic (3.53e-2)" "potential prognostic unfavorable (3.29e-6)" "unprognostic (3.45e-3)" "potential prognostic unfavorable (2.59e-4)" "unprognostic (1.12e-1)" "unprognostic (3.70e-2)" "unprognostic (5.43e-2)" "unprognostic (1.17e-1)" "unprognostic (9.14e-2)" "unprognostic (9.75e-2)" "unprognostic (3.08e-2)" "potential prognostic unfavorable (2.50e-6)" "unprognostic (2.22e-1)" "unprognostic (1.32e-1)" "unprognostic (2.74e-2)" "unprognostic (1.63e-1)" "unprognostic (4.95e-3)" "unprognostic (1.57e-1)" "unprognostic (8.12e-2)" "unprognostic (2.50e-1)" PEG3 "KIAA0287, ZKSCAN22, ZNF904, ZSCAN24" ENSG00000198300 "Paternally expressed 3" Q9GZU2 19 56810077-56840728 "Predicted intracellular proteins, Transcription factors" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 195.7;placenta: 126.9" "Cell type enhanced" "Detected in some" "Brain inhibitory neurons: 4.6;Cytotrophoblasts: 14.5;Early primary spermatocytes: 4.4;Gonadotrophs: 16.3;Late spermatids: 5.0;Migrating cytotrophoblasts: 13.4;Other brain neurons: 6.4;Ovarian stromal cells: 5.5;Retinal horizontal cells: 6.0;Syncytiotrophoblasts: 23.3" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 16.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 62.9;Rhabdoid: 163.0" "Adrenal gland - Adrenal cortex cells, Pituitary gland - Gonadotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026070 Approved Approved Nucleoplasm NA NA "Cluster 75: Ovary - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 4 Nucleoplasm "HPA026070: " "unprognostic (1.67e-2)" "unprognostic (1.17e-2)" "unprognostic (1.68e-1)" "unprognostic (1.11e-1)" "unprognostic (1.07e-1)" "unprognostic (1.86e-2)" "unprognostic (4.38e-2)" "unprognostic (2.75e-2)" "unprognostic (5.34e-2)" "unprognostic (1.23e-1)" "unprognostic (6.49e-3)" "unprognostic (2.23e-2)" "unprognostic (2.99e-1)" "unprognostic (2.68e-1)" "unprognostic (1.42e-2)" "unprognostic (3.41e-1)" "unprognostic (1.49e-1)" "unprognostic (6.21e-3)" "unprognostic (3.65e-2)" "unprognostic (2.27e-2)" "unprognostic (2.58e-1)" "potential prognostic unfavorable (5.78e-4)" PELI1 ENSG00000197329 "Pellino E3 ubiquitin protein ligase 1" Q96FA3 2 64092652-64144420 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "bone marrow: 215.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 1029.4;Esophageal apical cells: 1054.5;monocytes: 870.9;Neutrophils: 4332.1;Plasma cells: 1723.1;Transitional alveolar cells: 913.3" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 534.7;endothelial cell: 794.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 77.1" "Group enriched" "Detected in all" 4 "granulocytes: 77.1;monocytes: 23.3" "Cancer enhanced" "Detected in all" "lymphoma: 51.0" "Kidney - Endothelial cells, Liver - Neutrophils, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053182 Approved Supported "Nucleoplasm,Nucleoli,Intermediate filaments,Centriolar satellite,Centrosome,Basal body,Cytosol" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 55: Non-specific - Transcription" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 37 "Nucleoplasm, Nucleoli, Basal body" "Intermediate filaments, Centriolar satellite, Centrosome, Cytosol" "HPA053182: " "unprognostic (1.67e-1)" "unprognostic (2.24e-1)" "unprognostic (7.52e-3)" "unprognostic (1.95e-1)" "unprognostic (2.29e-1)" "unprognostic (8.53e-2)" "unprognostic (1.38e-1)" "unprognostic (5.38e-3)" "unprognostic (2.59e-2)" "unprognostic (1.24e-1)" "potential prognostic favorable (1.70e-4)" "unprognostic (5.46e-3)" "potential prognostic unfavorable (1.39e-4)" "unprognostic (1.48e-2)" "unprognostic (2.59e-1)" "unprognostic (6.91e-2)" "unprognostic (7.61e-2)" "unprognostic (3.67e-2)" "unprognostic (1.08e-1)" "unprognostic (2.03e-2)" "unprognostic (7.98e-3)" "unprognostic (1.51e-3)" "unprognostic (1.88e-1)" "unprognostic (3.12e-1)" "unprognostic (1.10e-1)" "unprognostic (1.61e-1)" "unprognostic (1.37e-1)" "unprognostic (9.19e-2)" "unprognostic (4.08e-2)" "unprognostic (1.18e-1)" "unprognostic (1.07e-1)" PELI2 ENSG00000139946 "Pellino E3 ubiquitin protein ligase family member 2" Q9HAT8 14 56117814-56301524 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 1062.9;Pancreatic acinar cells: 709.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 5.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Stomach - Gastric mucous cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053182 Uncertain Approved "Nucleoplasm,Nucleoli,Intermediate filaments,Centriolar satellite,Centrosome,Basal body,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 8: Pancreas - Proteolysis" "Cluster 25: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 29 "Nucleoplasm, Nucleoli, Basal body" "Intermediate filaments, Centriolar satellite, Centrosome, Cytosol" "HPA053182: " "unprognostic (6.81e-3)" "unprognostic (3.42e-1)" "unprognostic (1.02e-1)" "unprognostic (1.86e-1)" "unprognostic (2.97e-1)" "potential prognostic unfavorable (2.88e-4)" "unprognostic (7.98e-2)" "unprognostic (1.25e-2)" "unprognostic (3.36e-1)" "unprognostic (5.50e-2)" "validated prognostic favorable (8.33e-9)" "validated prognostic favorable (4.48e-4)" "unprognostic (3.34e-2)" "unprognostic (1.51e-2)" "unprognostic (2.53e-1)" "unprognostic (3.14e-2)" "potential prognostic favorable (8.44e-4)" "unprognostic (7.98e-3)" "unprognostic (2.71e-1)" "unprognostic (2.67e-1)" "unprognostic (1.70e-2)" "unprognostic (4.23e-1)" "unprognostic (1.10e-1)" "unprognostic (4.99e-2)" "unprognostic (7.34e-2)" "unprognostic (1.20e-1)" "unprognostic (1.58e-1)" "unprognostic (2.60e-2)" "unprognostic (1.29e-2)" PELI3 MGC35521 ENSG00000174516 "Pellino E3 ubiquitin protein ligase family member 3" Q8N2H9 11 66466327-66477337 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 38.3" "Cell type enhanced" "Detected in many" "Late spermatids: 15.8;Neuroendocrine cells: 20.9;Pancreatic islet cells: 19.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033750, HPA038875, HPA062281" Uncertain Approved Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 73: Brain - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 24: Non-specific - Unknown function" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" 7 "Nucleoplasm, Vesicles" Nucleoli "CAB033750: , HPA038875: , HPA062281: " "unprognostic (2.57e-1)" "unprognostic (1.99e-1)" "unprognostic (4.56e-2)" "unprognostic (3.05e-1)" "unprognostic (1.07e-1)" "unprognostic (1.64e-1)" "unprognostic (1.54e-2)" "unprognostic (3.32e-1)" "unprognostic (3.96e-2)" "unprognostic (2.04e-3)" "potential prognostic favorable (3.01e-5)" "unprognostic (7.50e-3)" "unprognostic (2.48e-1)" "unprognostic (7.59e-3)" "unprognostic (9.58e-2)" "unprognostic (5.24e-2)" "unprognostic (8.02e-3)" "unprognostic (2.92e-1)" "unprognostic (2.46e-2)" "unprognostic (2.01e-1)" "unprognostic (8.11e-2)" "unprognostic (1.40e-3)" "unprognostic (8.52e-2)" "unprognostic (2.82e-2)" "unprognostic (1.94e-1)" "unprognostic (1.06e-1)" "unprognostic (8.72e-2)" "unprognostic (7.21e-2)" "unprognostic (8.80e-2)" "unprognostic (9.77e-2)" "unprognostic (1.17e-1)" PELO ENSG00000152684 "Pelota mRNA surveillance and ribosome rescue factor" Q9BRX2 5 52787916-52804044 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Translation regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Gastric chief cells: 2.2;Hepatic stellate cells: 6.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031458, HPA073228" Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Mitotic chromosome" Yes NA "Cluster 35: Neutrophils - Protein binding" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 110: Mural cells - ECM organization" 33 "Nucleoli fibrillar center" "Nucleoplasm, Mitotic chromosome" "HPA031458: , HPA073228: " "unprognostic (6.28e-2)" "potential prognostic unfavorable (1.38e-5)" "unprognostic (3.27e-2)" "unprognostic (2.17e-2)" "unprognostic (1.39e-1)" "unprognostic (1.88e-1)" "unprognostic (2.37e-2)" "unprognostic (1.19e-3)" "unprognostic (3.46e-2)" "unprognostic (1.80e-2)" "potential prognostic favorable (6.63e-5)" "unprognostic (1.37e-2)" "unprognostic (1.11e-1)" "unprognostic (3.82e-3)" "potential prognostic unfavorable (7.75e-4)" "unprognostic (1.14e-2)" "potential prognostic unfavorable (1.74e-4)" "unprognostic (1.32e-2)" "unprognostic (2.51e-1)" "unprognostic (2.27e-2)" "unprognostic (4.51e-3)" "unprognostic (6.24e-2)" "unprognostic (3.09e-1)" "unprognostic (1.49e-1)" "unprognostic (2.28e-2)" "unprognostic (1.26e-1)" "unprognostic (2.10e-1)" "unprognostic (3.20e-1)" "unprognostic (7.63e-2)" "unprognostic (1.11e-2)" "unprognostic (2.87e-1)" PELP1 MNAR ENSG00000141456 "Proline, glutamate and leucine rich protein 1" Q8IZL8 17 4669774-4704337 "Essential proteins, Predicted intracellular proteins" Transcription "Activator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053966, HPA056028, HPA060760" Supported Enhanced Nucleoplasm,Nucleoli NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 71 "Nucleoplasm, Nucleoli" "HPA053966: , HPA056028: , HPA060760: " "unprognostic (1.05e-1)" "unprognostic (9.94e-2)" "unprognostic (8.00e-3)" "unprognostic (1.56e-2)" "unprognostic (8.90e-2)" "unprognostic (3.01e-2)" "unprognostic (1.37e-1)" "unprognostic (6.92e-2)" "unprognostic (2.25e-1)" "unprognostic (7.27e-2)" "unprognostic (3.13e-3)" "unprognostic (4.15e-3)" "unprognostic (9.48e-2)" "potential prognostic unfavorable (3.69e-4)" "unprognostic (2.48e-2)" "unprognostic (1.27e-2)" "unprognostic (6.36e-2)" "unprognostic (1.15e-1)" "unprognostic (5.69e-2)" "unprognostic (3.08e-1)" "unprognostic (3.15e-2)" "potential prognostic favorable (2.06e-4)" "unprognostic (8.49e-2)" "unprognostic (1.54e-2)" "unprognostic (1.97e-1)" "unprognostic (2.13e-1)" "unprognostic (2.94e-2)" "unprognostic (8.51e-2)" "unprognostic (3.58e-1)" "unprognostic (2.11e-1)" "unprognostic (6.69e-2)" PEMT "PEMPT, PEMT2" ENSG00000133027 "Phosphatidylethanolamine N-methyltransferase" Q9UBM1 17 17505563-17591708 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 156.9;liver: 259.1" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 439.5;Epididymal efferent duct absorptive cells: 375.8;Epididymal principal cells: 958.2;Hepatocytes: 271.9;Pancreatic islet cells: 231.8;Peritubular myoid cells: 361.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Pituitary gland - Corticotropes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042375, HPA073930" Approved Supported "Endoplasmic reticulum,Vesicles,Mitochondria,Cytosol" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 45: Non-specific - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" "Endoplasmic reticulum, Mitochondria" "Vesicles, Cytosol" "HPA042375: , HPA073930: " "potential prognostic unfavorable (1.06e-4)" "unprognostic (7.88e-2)" "unprognostic (1.10e-1)" "unprognostic (3.11e-1)" "unprognostic (3.87e-2)" "unprognostic (7.86e-2)" "unprognostic (2.66e-1)" "unprognostic (6.69e-2)" "unprognostic (3.77e-2)" "unprognostic (8.35e-2)" "unprognostic (7.30e-2)" "unprognostic (4.14e-2)" "unprognostic (2.42e-2)" "unprognostic (9.12e-2)" "unprognostic (4.50e-2)" "unprognostic (8.75e-2)" "unprognostic (1.81e-1)" "unprognostic (6.33e-2)" "unprognostic (9.94e-2)" "unprognostic (3.13e-1)" "unprognostic (2.66e-3)" "unprognostic (5.51e-3)" "unprognostic (1.10e-1)" "unprognostic (1.76e-1)" "unprognostic (1.62e-1)" "unprognostic (6.81e-2)" "unprognostic (1.15e-1)" "unprognostic (2.44e-1)" "unprognostic (2.02e-1)" "unprognostic (1.52e-1)" "unprognostic (4.59e-2)" PENK ENSG00000181195 Proenkephalin P01210 8 56436674-56446671 "Plasma proteins, Predicted secreted proteins, Transporters" "Endorphin, Neuropeptide, Opioid peptide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "adrenal gland: 355.7;brain: 673.6" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 372.3;Brain inhibitory neurons: 114.2;Early primary spermatocytes: 128.7;Early spermatids: 67.1;Late primary spermatocytes: 456.2;Leydig cells: 922.0;Peritubular myoid cells: 213.7" "Group enriched" "Detected in many" 5 "eccentric medium spiny neuron: 116.6;medium spiny neuron: 341.4" "Cancer enhanced" "Detected in many" "Lung Squamous Cell Carcinoma (TCGA): 34.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Rhabdoid: 795.3" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Testis - Early spermatids" "Region enriched" "Detected in all" 7 "basal ganglia: 3628.7" "Region enriched" "Detected in all" 7 "basal ganglia: 1199.3" "HPA013138, CAB016390" Enhanced Approved Vesicles "Secreted in other tissues" Neuropeptide NA NA 130000 "Cluster 40: Monocytes - Innate immune response" "Cluster 36: Brain & Liver - Signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 94: Gonadal somatic cells - Mixed function" Vesicles "CAB016390: , HPA013138: " "unprognostic (4.43e-2)" "unprognostic (1.31e-2)" "unprognostic (3.59e-1)" "unprognostic (2.17e-2)" "unprognostic (6.48e-3)" "unprognostic (2.52e-2)" "unprognostic (3.78e-2)" "unprognostic (5.93e-2)" "unprognostic (9.49e-2)" "unprognostic (2.75e-1)" "unprognostic (1.27e-1)" "unprognostic (3.00e-1)" "unprognostic (3.93e-2)" "unprognostic (1.71e-1)" "unprognostic (4.29e-2)" "unprognostic (1.85e-3)" "unprognostic (1.96e-1)" "unprognostic (3.48e-2)" "unprognostic (3.95e-2)" PEPD ENSG00000124299 "Peptidase D" P12955 19 33386950-33521823 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Collagen degradation" "Dipeptidase, Hydrolase, Metalloprotease, Protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 201.1;kidney: 310.3" "Cell type enhanced" "Detected in many" "Enterocytes: 849.5;Hepatocytes: 210.4;Hofbauer cells: 394.7;Proximal tubule cells: 197.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Macrophages, Pancreas - Macrophages, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015599, HPA072045" Enhanced Approved Nucleoplasm NA NA 250000000 "Cluster 33: Non-specific - ATP binding" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 27: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 1: Enterocytes - Absorption and Digestion" 3 Nucleoplasm "HPA015599: , HPA072045: " "unprognostic (4.73e-3)" "unprognostic (1.53e-1)" "unprognostic (2.74e-1)" "unprognostic (5.38e-1)" "unprognostic (3.39e-1)" "unprognostic (2.90e-2)" "unprognostic (2.25e-1)" "unprognostic (8.73e-3)" "unprognostic (2.83e-1)" "unprognostic (2.86e-1)" "potential prognostic favorable (1.87e-7)" "unprognostic (1.48e-1)" "unprognostic (6.23e-2)" "unprognostic (2.40e-1)" "unprognostic (1.52e-2)" "unprognostic (3.49e-1)" "unprognostic (9.54e-2)" "unprognostic (1.37e-1)" "unprognostic (9.67e-2)" "unprognostic (7.14e-2)" "unprognostic (9.27e-2)" "unprognostic (1.04e-2)" "unprognostic (6.66e-2)" "unprognostic (3.80e-1)" "unprognostic (1.15e-1)" "unprognostic (2.76e-2)" "unprognostic (7.74e-2)" "unprognostic (2.38e-2)" "unprognostic (1.97e-1)" "unprognostic (1.23e-1)" "unprognostic (2.10e-1)" PER1 "PER, RIGUI" ENSG00000179094 "Period circadian regulator 1" O15534 17 8140472-8156506 "Cancer-related genes, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pituicytes/FSCs: 294.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047947, HPA067064" Supported Nucleoplasm,Cytosol NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 24: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 42: Non-specific - Unknown function" "Cluster 103: Non-specific - Basic cellular processes" 54 Cytosol Nucleoplasm "HPA047947: , HPA067064: " "unprognostic (3.67e-3)" "unprognostic (3.57e-2)" "unprognostic (6.95e-2)" "unprognostic (1.36e-2)" "unprognostic (1.64e-1)" "unprognostic (2.53e-1)" "unprognostic (2.21e-1)" "unprognostic (1.53e-1)" "unprognostic (2.62e-2)" "unprognostic (2.12e-1)" "unprognostic (1.62e-3)" "unprognostic (9.17e-3)" "potential prognostic favorable (2.18e-4)" "validated prognostic favorable (2.29e-4)" "validated prognostic favorable (1.40e-4)" "unprognostic (5.32e-2)" "unprognostic (6.17e-2)" "unprognostic (5.16e-2)" "unprognostic (2.60e-1)" "unprognostic (7.47e-3)" "unprognostic (3.31e-3)" "unprognostic (3.74e-2)" "unprognostic (1.73e-1)" "unprognostic (1.14e-1)" "unprognostic (4.29e-1)" "unprognostic (1.45e-2)" "unprognostic (9.55e-2)" "unprognostic (2.14e-3)" "unprognostic (1.63e-1)" "unprognostic (3.53e-2)" "unprognostic (1.29e-1)" PER2 KIAA0347 ENSG00000132326 "Period circadian regulator 2" O15055 2 238244044-238290102 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Respiratory basal cells: 338.0;Respiratory secretory cells: 282.8;Salivary basal cells: 290.3;Salivary myoepithelial cells: 278.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Breast - Breast myoepithelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053136, HPA060510" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 21: Testis - Mixed function" "Cluster 2: Neurons - Nucleosome" "Cluster 54: Non-specific - Transcription" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 27 Nucleoplasm Cytosol "HPA053136: , HPA060510: " "unprognostic (1.23e-2)" "unprognostic (1.91e-1)" "unprognostic (2.56e-1)" "unprognostic (3.02e-1)" "unprognostic (3.83e-1)" "unprognostic (1.33e-1)" "unprognostic (3.55e-1)" "unprognostic (1.08e-1)" "unprognostic (1.57e-3)" "unprognostic (4.68e-2)" "potential prognostic favorable (1.29e-5)" "unprognostic (2.16e-3)" "unprognostic (5.52e-2)" "unprognostic (3.68e-2)" "unprognostic (2.07e-1)" "unprognostic (1.09e-1)" "unprognostic (1.00e-1)" "unprognostic (1.17e-1)" "potential prognostic favorable (2.12e-5)" "unprognostic (5.12e-2)" "unprognostic (4.66e-2)" "unprognostic (7.31e-2)" "unprognostic (1.92e-1)" "unprognostic (6.81e-2)" "unprognostic (1.53e-1)" "unprognostic (1.28e-1)" "unprognostic (1.84e-3)" "unprognostic (3.60e-1)" "unprognostic (2.75e-2)" "unprognostic (6.87e-2)" "unprognostic (1.43e-1)" PER3 ENSG00000049246 "Period circadian regulator 3" P56645 1 7784291-7845177 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bergmann glia: 354.9;Lactotrophs: 335.7;Müller glia: 437.2;Myonuclei: 369.4;Retinal bipolar cells: 805.9;Retinal horizontal cells: 402.7;Rod photoreceptor cells: 444.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019530 Approved Supported Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 2: Neurons - Nucleosome" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 4 Cytosol "HPA019530: " "potential prognostic favorable (5.59e-4)" "unprognostic (1.58e-1)" "unprognostic (4.13e-2)" "unprognostic (1.80e-2)" "unprognostic (2.80e-1)" "unprognostic (2.79e-1)" "unprognostic (2.15e-1)" "unprognostic (4.79e-2)" "unprognostic (2.15e-3)" "unprognostic (7.31e-2)" "potential prognostic favorable (7.35e-7)" "unprognostic (2.18e-3)" "unprognostic (1.67e-2)" "unprognostic (3.60e-1)" "unprognostic (1.22e-1)" "unprognostic (2.34e-2)" "unprognostic (2.47e-1)" "unprognostic (1.06e-1)" "unprognostic (2.24e-2)" "unprognostic (1.53e-1)" "unprognostic (1.43e-1)" "unprognostic (2.09e-1)" "unprognostic (2.86e-1)" "unprognostic (8.65e-2)" "unprognostic (1.54e-1)" "unprognostic (5.29e-2)" "unprognostic (4.01e-2)" "unprognostic (4.48e-2)" "unprognostic (1.48e-1)" "unprognostic (1.80e-1)" "unprognostic (1.55e-3)" PERCC1 ENSG00000284395 "Proline and glutamate rich with coiled coil 1" A0A1W2PR82 16 1431078-1434441 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "prostate: 1.7;stomach 1: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Prostate Adenocarcinoma (TCGA): 6.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Sarcoma: 6.3;thyroid cancer: 17.1" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Stomach - Gastric enteroendocrine cells" "Not detected" "Not detected" "Region enriched" "Detected in some" 5 "cerebellum: 5.3" NA NA "Cluster 38: Non-specific - Basic cellular processes" "Cluster 37: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" "unprognostic (4.06e-1)" "unprognostic (8.47e-2)" PERM1 "C1orf170, MGC13275, RP11-54O7.8" ENSG00000187642 "PPARGC1 and ESRR induced regulator, muscle 1" Q5SV97 1 975198-982117 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 56 "heart muscle: 64.2;skeletal muscle: 168.4;tongue: 126.9" "Group enriched" "Detected in some" 7 "Cardiomyocytes: 74.1;Myonuclei: 76.7" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Kidney Renal Clear Cell Carcinoma (TCGA): 2.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA031711, HPA031712" Enhanced Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 55: Myocytes - Oxidative muscle function" Nucleoplasm "Nuclear bodies" "HPA031711: , HPA031712: " "unprognostic (1.01e-1)" "unprognostic (2.37e-1)" "unprognostic (2.06e-1)" PERP "dJ496H19.1, KCP1, KRTCAP1, PIGPC1, THW" ENSG00000112378 "P53 apoptosis effector related to PMP22" Q96FX8 6 138088505-138107419 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Apoptosis, Cell adhesion" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "cervix: 309.5;esophagus: 758.5;salivary gland: 274.1;skin 1: 1079.2;vagina: 423.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 3219.0;Esophageal apical cells: 18030.6;Esophageal basal cells: 3681.7;Esophageal suprabasal cells: 9964.4;Ocular epithelial cells: 3889.4;Suprabasal keratinocytes: 6970.5" "Cell type enhanced" "Detected in many" "endothelial cell: 97.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 40.0" "Lineage enriched" "Detected in many" 4 "granulocytes: 40.0" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022269 Enhanced NA NA "Cluster 32: Basophils - Transcription" "Cluster 58: Skin - Keratinization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 7 "HPA022269: " "unprognostic (1.90e-1)" "potential prognostic unfavorable (8.66e-4)" "unprognostic (1.38e-1)" "unprognostic (3.09e-1)" "unprognostic (1.84e-1)" "unprognostic (2.88e-3)" "unprognostic (1.47e-1)" "potential prognostic unfavorable (2.44e-4)" "unprognostic (2.95e-2)" "unprognostic (4.02e-1)" "unprognostic (7.97e-2)" "unprognostic (8.22e-2)" "unprognostic (6.71e-2)" "unprognostic (2.93e-3)" "unprognostic (4.27e-3)" "potential prognostic unfavorable (1.60e-7)" "unprognostic (3.37e-2)" "unprognostic (1.61e-2)" "unprognostic (2.40e-2)" "unprognostic (2.78e-2)" "unprognostic (2.39e-2)" "potential prognostic unfavorable (2.60e-5)" "unprognostic (2.44e-3)" "unprognostic (1.44e-1)" "unprognostic (2.04e-1)" "unprognostic (4.61e-2)" "unprognostic (7.74e-2)" "unprognostic (4.22e-2)" "unprognostic (2.32e-1)" "unprognostic (2.26e-1)" "unprognostic (7.92e-2)" PES1 "NOP7, PES" ENSG00000100029 "Pescadillo ribosomal biogenesis factor 1" O00541 22 30576625-30607083 "Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cell type enhanced" "Detected in all" "endothelial cell: 38.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040210, HPA062439, HPA066670" Supported Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes Yes "Cluster 13: Non-specific - Mitochondria" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 58 "Nucleoli, Nucleoli rim, Mitotic chromosome" Nucleoplasm "HPA040210: , HPA062439: , HPA066670: " "unprognostic (1.48e-1)" "unprognostic (1.78e-1)" "unprognostic (1.07e-1)" "unprognostic (1.78e-2)" "unprognostic (2.09e-1)" "unprognostic (1.22e-1)" "unprognostic (1.64e-1)" "unprognostic (1.51e-1)" "unprognostic (1.60e-3)" "unprognostic (3.57e-2)" "unprognostic (2.44e-2)" "unprognostic (1.04e-1)" "unprognostic (1.08e-2)" "validated prognostic unfavorable (8.03e-10)" "validated prognostic unfavorable (1.40e-5)" "potential prognostic unfavorable (5.39e-4)" "unprognostic (2.55e-3)" "unprognostic (3.15e-2)" "unprognostic (1.86e-3)" "unprognostic (2.89e-1)" "unprognostic (1.18e-1)" "unprognostic (1.05e-2)" "unprognostic (3.70e-2)" "unprognostic (1.53e-1)" "unprognostic (1.26e-3)" "unprognostic (4.19e-2)" "unprognostic (7.97e-2)" "unprognostic (6.89e-2)" "unprognostic (2.21e-1)" "unprognostic (9.64e-2)" "unprognostic (1.81e-2)" PET100 C19orf79 ENSG00000229833 "PET100 cytochrome c oxidase chaperone" P0DJ07 19 7629788-7631956 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 224.0" "Cell type enhanced" "Detected in many" "Gastric chief cells: 321.1;Hepatocytes: 484.9;Parietal cells: 431.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067288 Approved Mitochondria NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 21: Non-specific - Metabolism" "Cluster 23: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" Mitochondria "HPA067288: " "potential prognostic favorable (8.15e-4)" "unprognostic (6.50e-2)" "unprognostic (2.71e-1)" "unprognostic (8.82e-2)" "unprognostic (2.68e-3)" "unprognostic (1.66e-1)" "unprognostic (1.48e-1)" "unprognostic (7.87e-2)" "unprognostic (8.88e-3)" "unprognostic (8.90e-2)" "unprognostic (3.12e-1)" "unprognostic (1.92e-2)" "unprognostic (1.14e-1)" "unprognostic (4.22e-2)" "unprognostic (3.64e-1)" "unprognostic (1.15e-2)" "unprognostic (1.60e-1)" "unprognostic (3.44e-3)" "unprognostic (1.31e-1)" "unprognostic (5.67e-2)" "unprognostic (5.21e-2)" "unprognostic (1.59e-2)" "unprognostic (1.98e-1)" "unprognostic (5.04e-2)" "unprognostic (2.58e-2)" "unprognostic (2.25e-2)" "unprognostic (1.78e-2)" "unprognostic (5.23e-2)" "unprognostic (1.64e-2)" PET117 CSRP2BP ENSG00000232838 "PET117 cytochrome c oxidase chaperone" Q6UWS5 20 18137863-18143169 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA047716 Approved "Intracellular and membrane" "No annotated function" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 76: Non-specific - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 105: Non-specific - Mixed function" "HPA047716: " "unprognostic (9.20e-2)" "unprognostic (9.06e-2)" "unprognostic (1.53e-2)" "unprognostic (1.48e-1)" "unprognostic (2.03e-1)" "unprognostic (6.36e-2)" "unprognostic (2.95e-2)" "unprognostic (4.54e-2)" "potential prognostic unfavorable (2.40e-4)" "unprognostic (1.26e-3)" "unprognostic (5.88e-2)" "unprognostic (2.39e-1)" "validated prognostic unfavorable (2.82e-7)" "validated prognostic unfavorable (2.68e-4)" "unprognostic (1.85e-1)" "unprognostic (2.49e-1)" "unprognostic (3.19e-2)" "unprognostic (2.87e-1)" "unprognostic (3.59e-2)" "unprognostic (9.11e-2)" "unprognostic (2.11e-1)" "unprognostic (1.25e-1)" "unprognostic (1.83e-1)" "unprognostic (8.69e-3)" "unprognostic (8.66e-2)" "unprognostic (1.96e-1)" "unprognostic (3.23e-1)" "unprognostic (1.65e-1)" "unprognostic (3.69e-1)" "unprognostic (1.09e-1)" PEX1 "ZWS, ZWS1" ENSG00000127980 "Peroxisomal biogenesis factor 1" O43933 7 92487020-92528520 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Peroxisome biogenesis, Protein transport, Transport" Hydrolase "Amelogenesis imperfecta, Deafness, Disease variant, Peroxisome biogenesis disorder, Zellweger syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 158.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020235 Approved Supported Peroxisomes NA NA "Cluster 24: Non-specific - Transcription" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 60 Peroxisomes "HPA020235: " "unprognostic (3.74e-1)" "unprognostic (8.43e-2)" "unprognostic (2.61e-1)" "unprognostic (2.96e-2)" "unprognostic (1.34e-2)" "unprognostic (1.12e-1)" "unprognostic (2.62e-2)" "unprognostic (1.11e-1)" "unprognostic (2.48e-1)" "unprognostic (5.28e-3)" "potential prognostic favorable (2.12e-7)" "unprognostic (1.85e-2)" "unprognostic (5.15e-2)" "unprognostic (1.97e-2)" "unprognostic (4.93e-1)" "unprognostic (6.34e-2)" "unprognostic (6.82e-2)" "unprognostic (8.68e-3)" "unprognostic (7.36e-2)" "unprognostic (1.17e-1)" "unprognostic (2.32e-1)" "unprognostic (1.41e-2)" "unprognostic (3.38e-2)" "unprognostic (2.41e-1)" "unprognostic (2.43e-1)" "unprognostic (2.52e-1)" "unprognostic (3.50e-1)" "unprognostic (1.30e-1)" "unprognostic (4.76e-1)" "potential prognostic unfavorable (7.98e-4)" "unprognostic (3.56e-2)" PEX10 RNF69 ENSG00000157911 "Peroxisomal biogenesis factor 10" O60683 1 2403964-2413797 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Peroxisome biogenesis, Protein transport, Transport, Ubl conjugation pathway" Transferase "Disease variant, Peroxisome biogenesis disorder, Zellweger syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Late spermatids: 366.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049755 Approved NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 3 "HPA049755: " "unprognostic (3.43e-1)" "unprognostic (3.02e-3)" "unprognostic (1.08e-1)" "unprognostic (1.44e-2)" "unprognostic (3.02e-1)" "unprognostic (1.11e-1)" "unprognostic (3.89e-1)" "unprognostic (2.84e-1)" "unprognostic (3.42e-1)" "unprognostic (6.43e-2)" "potential prognostic favorable (1.26e-6)" "unprognostic (1.16e-1)" "potential prognostic favorable (2.00e-4)" "unprognostic (7.17e-3)" "potential prognostic unfavorable (4.98e-5)" "unprognostic (4.34e-1)" "unprognostic (4.00e-1)" "unprognostic (1.58e-1)" "unprognostic (8.89e-2)" "unprognostic (1.61e-1)" "unprognostic (1.20e-1)" "unprognostic (1.24e-1)" "unprognostic (2.63e-1)" "unprognostic (2.12e-1)" "unprognostic (6.10e-2)" "unprognostic (2.57e-3)" "unprognostic (3.82e-2)" "unprognostic (1.21e-1)" "unprognostic (2.11e-1)" "unprognostic (1.20e-1)" "unprognostic (1.79e-1)" PEX11A "MGC119947, MGC138534, PEX11alpha, PMP28" ENSG00000166821 "Peroxisomal biogenesis factor 11 alpha" O75192 15 89677764-89690783 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Peroxisome biogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 49.7;Hepatocytes: 47.9;Late spermatids: 60.2;Prostatic club cells: 57.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Skin - Sebaceous gland cells, Spleen - Fibroblasts_2, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 27: Breast cancer - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 2 "unprognostic (3.63e-2)" "unprognostic (4.58e-2)" "unprognostic (1.46e-1)" "unprognostic (2.58e-2)" "unprognostic (1.08e-1)" "unprognostic (1.62e-3)" "unprognostic (1.39e-1)" "unprognostic (5.33e-2)" "potential prognostic unfavorable (2.69e-4)" "unprognostic (5.87e-2)" "potential prognostic favorable (4.82e-9)" "unprognostic (5.82e-3)" "unprognostic (9.17e-2)" "unprognostic (1.90e-1)" "unprognostic (1.12e-1)" "unprognostic (5.44e-2)" "unprognostic (1.14e-1)" "unprognostic (5.76e-2)" "unprognostic (7.10e-2)" "unprognostic (1.52e-1)" "unprognostic (2.07e-1)" "unprognostic (3.79e-2)" "unprognostic (2.99e-1)" "unprognostic (3.22e-1)" "unprognostic (4.55e-2)" "unprognostic (5.70e-3)" "unprognostic (1.63e-2)" "unprognostic (2.80e-2)" "unprognostic (1.43e-1)" "unprognostic (2.03e-1)" "unprognostic (1.85e-2)" PEX11B PEX11beta ENSG00000131779 "Peroxisomal biogenesis factor 11 beta" O96011 1 145911350-145918717 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Peroxisome biogenesis" "Peroxisome biogenesis disorder" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017150, HPA050104" Supported Approved Nucleoplasm,Vesicles NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 97: Non-specific - Cellular respiration" 3 Vesicles Nucleoplasm "HPA017150: , HPA050104: " "unprognostic (6.38e-2)" "unprognostic (1.47e-1)" "unprognostic (4.42e-1)" "unprognostic (3.65e-1)" "unprognostic (1.41e-2)" "unprognostic (3.11e-2)" "unprognostic (1.24e-1)" "unprognostic (1.86e-2)" "unprognostic (2.14e-1)" "unprognostic (9.30e-3)" "potential prognostic favorable (4.94e-5)" "unprognostic (2.86e-2)" "unprognostic (2.68e-2)" "unprognostic (1.15e-3)" "unprognostic (2.23e-1)" "unprognostic (2.90e-2)" "unprognostic (2.01e-1)" "unprognostic (1.37e-2)" "unprognostic (1.19e-1)" "unprognostic (2.22e-2)" "unprognostic (5.85e-3)" "unprognostic (1.54e-1)" "unprognostic (4.42e-2)" "unprognostic (1.21e-1)" "unprognostic (3.21e-1)" "unprognostic (3.51e-2)" "unprognostic (1.03e-1)" "unprognostic (3.33e-1)" "unprognostic (7.41e-2)" "unprognostic (9.13e-2)" "unprognostic (2.89e-1)" PEX11G PEX11gamma ENSG00000104883 "Peroxisomal biogenesis factor 11 gamma" Q96HA9 19 7476875-7497449 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 25.2;testis: 27.7" "Cell type enhanced" "Detected in many" "Early spermatids: 138.1;Endometrial luminal cells: 49.3;Late primary spermatocytes: 67.2;Late spermatids: 121.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 24.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA069817 Uncertain NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 67: Testis - Mixed function" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 5 "HPA069817: " "unprognostic (3.16e-2)" "unprognostic (8.05e-2)" "unprognostic (3.68e-1)" "unprognostic (1.42e-2)" "unprognostic (1.91e-1)" "unprognostic (1.32e-1)" "unprognostic (1.05e-1)" "unprognostic (1.88e-1)" "unprognostic (3.67e-3)" "unprognostic (2.49e-2)" "potential prognostic favorable (6.45e-7)" "unprognostic (1.26e-3)" "potential prognostic favorable (8.63e-9)" "validated prognostic favorable (5.90e-4)" "validated prognostic favorable (4.88e-4)" "unprognostic (9.55e-2)" "unprognostic (2.15e-1)" "unprognostic (1.59e-1)" "unprognostic (3.04e-1)" "unprognostic (1.30e-1)" "unprognostic (9.35e-2)" "unprognostic (1.47e-2)" "unprognostic (8.04e-2)" "unprognostic (2.67e-1)" "unprognostic (6.34e-2)" "unprognostic (6.02e-2)" "unprognostic (1.34e-2)" "unprognostic (1.42e-2)" "unprognostic (1.32e-1)" "unprognostic (9.12e-2)" "unprognostic (5.97e-3)" PEX12 ENSG00000108733 "Peroxisomal biogenesis factor 12" O00623 17 35574795-35578863 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport, Ubl conjugation pathway" "Disease variant, Peroxisome biogenesis disorder, Zellweger syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 15.1;Early primary spermatocytes: 22.8;Early spermatids: 26.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069386 Enhanced NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 22: Epididymis - Mixed function" "Cluster 55: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 36 "HPA069386: " "unprognostic (8.51e-2)" "unprognostic (1.26e-2)" "unprognostic (2.95e-1)" "unprognostic (2.69e-1)" "unprognostic (2.47e-1)" "unprognostic (1.25e-1)" "unprognostic (7.25e-2)" "unprognostic (1.74e-1)" "unprognostic (3.67e-2)" "unprognostic (2.00e-1)" "potential prognostic favorable (3.12e-7)" "unprognostic (1.81e-2)" "unprognostic (9.25e-2)" "unprognostic (2.29e-1)" "unprognostic (2.73e-1)" "unprognostic (9.67e-2)" "unprognostic (6.10e-2)" "unprognostic (4.27e-2)" "unprognostic (3.10e-1)" "unprognostic (1.05e-1)" "unprognostic (9.79e-3)" "unprognostic (1.41e-1)" "unprognostic (2.83e-1)" "unprognostic (1.43e-2)" "unprognostic (1.27e-3)" "unprognostic (1.97e-1)" "unprognostic (1.80e-1)" "unprognostic (2.80e-1)" "unprognostic (3.87e-1)" "unprognostic (2.68e-1)" "unprognostic (1.41e-1)" PEX13 ENSG00000162928 "Peroxisomal biogenesis factor 13" Q92968 2 61017225-61051990 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Translocation, Transport" "Disease variant, Peroxisome biogenesis disorder, Zellweger syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 161.8;Urothelial cells: 186.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "HPA032141, HPA032142, CAB032689" Enhanced Supported Peroxisomes NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 31: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 69: Urothelial cells - Basic cellular functions" 11 Peroxisomes "CAB032689: , HPA032141: , HPA032142: " "unprognostic (9.67e-2)" "unprognostic (5.47e-2)" "unprognostic (7.92e-2)" "unprognostic (1.25e-2)" "unprognostic (2.01e-1)" "unprognostic (2.65e-2)" "unprognostic (2.76e-1)" "unprognostic (1.16e-1)" "unprognostic (2.19e-2)" "unprognostic (1.15e-3)" "unprognostic (2.75e-2)" "unprognostic (3.33e-3)" "unprognostic (1.41e-1)" "unprognostic (1.68e-3)" "unprognostic (9.10e-2)" "unprognostic (1.88e-1)" "unprognostic (4.51e-2)" "unprognostic (7.79e-2)" "unprognostic (3.19e-1)" "unprognostic (7.86e-2)" "unprognostic (2.36e-2)" "potential prognostic unfavorable (5.09e-4)" "unprognostic (8.95e-3)" "unprognostic (4.88e-2)" "unprognostic (3.33e-2)" "unprognostic (3.94e-2)" "unprognostic (1.21e-2)" "unprognostic (1.22e-1)" "unprognostic (2.60e-1)" "unprognostic (1.30e-1)" "unprognostic (2.57e-1)" PEX14 ENSG00000142655 "Peroxisomal biogenesis factor 14" O75381 1 10472288-10630758 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Protein transport, Translocation, Transport" "Peroxisome biogenesis disorder, Zellweger syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 423.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046104, HPA049231" Supported Supported "Nucleoli fibrillar center,Peroxisomes" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 37: Non-specific - mRNA processing" "Cluster 79: Photoreceptor cells - Phototransduction" 34 Peroxisomes "Nucleoli fibrillar center" "HPA046104: , HPA049231: " "unprognostic (7.72e-3)" "unprognostic (8.44e-2)" "unprognostic (5.92e-2)" "unprognostic (3.60e-2)" "unprognostic (1.67e-1)" "unprognostic (1.35e-1)" "unprognostic (2.67e-1)" "unprognostic (3.12e-2)" "unprognostic (1.70e-1)" "unprognostic (4.34e-2)" "unprognostic (3.85e-3)" "unprognostic (4.98e-2)" "potential prognostic favorable (4.93e-5)" "unprognostic (8.27e-2)" "unprognostic (8.78e-2)" "unprognostic (4.05e-2)" "unprognostic (4.06e-1)" "unprognostic (6.79e-2)" "unprognostic (6.45e-2)" "unprognostic (1.06e-1)" "unprognostic (7.50e-2)" "unprognostic (2.11e-1)" "unprognostic (3.11e-1)" "unprognostic (2.98e-1)" "unprognostic (1.18e-2)" "unprognostic (6.86e-3)" "unprognostic (2.82e-1)" "unprognostic (1.14e-2)" "potential prognostic favorable (4.11e-4)" "unprognostic (4.25e-1)" "unprognostic (3.08e-2)" PEX16 ENSG00000121680 "Peroxisomal biogenesis factor 16" Q9Y5Y5 11 45909663-45918812 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Peroxisome biogenesis" "Disease variant, Peroxisome biogenesis disorder, Zellweger syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 93.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Skin - Sebaceous gland cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043286 Approved NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 28 "HPA043286: " "unprognostic (5.74e-2)" "unprognostic (1.77e-1)" "unprognostic (3.20e-2)" "unprognostic (4.60e-2)" "unprognostic (3.22e-1)" "unprognostic (1.47e-1)" "unprognostic (1.36e-2)" "unprognostic (1.31e-2)" "unprognostic (8.13e-2)" "unprognostic (5.88e-3)" "unprognostic (3.01e-2)" "unprognostic (7.08e-2)" "potential prognostic favorable (3.60e-4)" "unprognostic (1.06e-3)" "unprognostic (2.58e-1)" "unprognostic (2.65e-1)" "unprognostic (1.09e-1)" "unprognostic (1.03e-1)" "unprognostic (3.20e-1)" "unprognostic (3.87e-2)" "unprognostic (1.32e-1)" "unprognostic (6.54e-3)" "unprognostic (3.23e-1)" "unprognostic (8.58e-2)" "unprognostic (1.27e-1)" "unprognostic (1.43e-1)" "unprognostic (4.78e-1)" "unprognostic (6.34e-3)" "unprognostic (1.23e-1)" "unprognostic (3.91e-2)" "unprognostic (1.46e-1)" PEX19 "D1S2223E, HK33, PMP1, PMPI, PXF, PXMP1" ENSG00000162735 "Peroxisomal biogenesis factor 19" P40855 1 160276807-160286348 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Host-virus interaction, Peroxisome biogenesis" "Peroxisome biogenesis disorder, Zellweger syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 14.1;Hepatic stellate cells: 6.5;Megakaryocytes: 6.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044837, HPA051966" Supported Supported Peroxisomes NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 27: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 89: Adipocytes - Lipid metabolism" 93 Peroxisomes "HPA044837: , HPA051966: " "unprognostic (4.04e-2)" "unprognostic (5.04e-3)" "unprognostic (3.24e-1)" "unprognostic (6.02e-2)" "unprognostic (1.38e-1)" "unprognostic (7.92e-2)" "unprognostic (1.53e-1)" "unprognostic (2.52e-2)" "unprognostic (1.31e-1)" "unprognostic (1.42e-2)" "potential prognostic favorable (6.86e-5)" "unprognostic (7.05e-3)" "unprognostic (1.57e-1)" "unprognostic (1.91e-1)" "unprognostic (2.80e-2)" "unprognostic (2.00e-1)" "unprognostic (1.89e-2)" "unprognostic (1.47e-2)" "unprognostic (2.33e-1)" "unprognostic (3.41e-2)" "unprognostic (4.45e-3)" "unprognostic (1.03e-2)" "unprognostic (8.96e-2)" "unprognostic (1.33e-1)" "unprognostic (2.53e-1)" "unprognostic (3.48e-2)" "unprognostic (5.25e-2)" "unprognostic (4.52e-2)" "unprognostic (3.16e-1)" "unprognostic (1.85e-1)" "unprognostic (1.46e-1)" PEX2 "PAF-1, PMP35, PXMP3, RNF72, ZWS3" ENSG00000164751 "Peroxisomal biogenesis factor 2" P28328 8 76980258-77001044 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Peroxisome biogenesis, Protein transport, Transport, Ubl conjugation pathway" Transferase "Disease variant, Peroxisome biogenesis disorder, Zellweger syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010983, HPA011410, HPA027729" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 3 Vesicles Nucleoplasm "HPA010983: , HPA011410: , HPA027729: " "unprognostic (8.03e-2)" "unprognostic (2.59e-2)" "unprognostic (3.98e-1)" "unprognostic (2.66e-1)" "unprognostic (1.36e-1)" "unprognostic (1.39e-2)" "unprognostic (1.78e-1)" "unprognostic (5.98e-2)" "unprognostic (1.68e-1)" "unprognostic (7.50e-2)" "potential prognostic favorable (2.70e-8)" "unprognostic (7.77e-3)" "unprognostic (1.31e-1)" "unprognostic (2.33e-1)" "unprognostic (1.58e-1)" "unprognostic (3.08e-1)" "unprognostic (5.06e-1)" "unprognostic (1.14e-1)" "unprognostic (6.39e-2)" "unprognostic (3.40e-2)" "unprognostic (1.26e-2)" "unprognostic (3.14e-3)" "unprognostic (2.33e-1)" "unprognostic (7.13e-2)" "unprognostic (6.73e-3)" "unprognostic (1.11e-1)" "unprognostic (1.25e-2)" "unprognostic (2.62e-2)" "unprognostic (1.93e-1)" "unprognostic (1.43e-2)" "unprognostic (4.70e-2)" PEX26 FLJ20695 ENSG00000215193 "Peroxisomal biogenesis factor 26" Q7Z412 22 18077923-18105396 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Disease variant, Peroxisome biogenesis disorder, Zellweger syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 12.3;Bergmann glia: 15.0;Brain excitatory neurons: 21.2;Brain inhibitory neurons: 21.1;Choroid plexus epithelial cells: 31.1;Distal convoluted tubule cells: 27.6;Ependymal cells: 12.5;Loop of henle epithelial cells: 28.7;Microglia: 23.3;Oligodendrocyte progenitor cells: 15.1;Oligodendrocytes: 18.4;Other brain neurons: 17.8;Papillary tip epithelial cells: 19.3;Podocytes: 21.9;Proximal tubule cells: 34.3;Renal collecting duct intercalated cells: 30.6;Renal collecting duct principal cells: 23.7;Renal connecting tubule cells: 29.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB070429 Approved NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 77: Intestine - Digestion" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 102: Non-specific - Mixed function" 35 "CAB070429: " "unprognostic (1.58e-1)" "unprognostic (2.53e-1)" "unprognostic (1.07e-1)" "unprognostic (2.71e-2)" "unprognostic (5.46e-3)" "unprognostic (3.34e-2)" "unprognostic (6.89e-2)" "unprognostic (6.75e-2)" "unprognostic (2.85e-1)" "unprognostic (3.35e-3)" "potential prognostic favorable (1.11e-5)" "unprognostic (2.62e-3)" "unprognostic (2.20e-2)" "unprognostic (3.47e-2)" "unprognostic (1.66e-3)" "unprognostic (3.63e-2)" "unprognostic (3.73e-3)" "unprognostic (1.20e-1)" "unprognostic (5.86e-3)" "unprognostic (1.55e-1)" "unprognostic (3.63e-1)" "unprognostic (1.51e-3)" "unprognostic (1.03e-1)" "unprognostic (1.87e-1)" "unprognostic (5.61e-3)" "unprognostic (9.73e-2)" "unprognostic (2.05e-1)" "unprognostic (8.64e-3)" "unprognostic (4.17e-2)" "unprognostic (3.56e-2)" "unprognostic (4.42e-2)" PEX3 ENSG00000034693 "Peroxisomal biogenesis factor 3" P56589 6 143450805-143490616 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Peroxisome biogenesis" "Disease variant, Peroxisome biogenesis disorder, Zellweger syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 113.3;Pituitary stem cells: 121.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042830, HPA058006" Supported Approved Nucleoplasm,Peroxisomes NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 76: Non-specific - Metabolism" "Cluster 31: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 36 "Nucleoplasm, Peroxisomes" "HPA042830: , HPA058006: " "unprognostic (2.65e-1)" "unprognostic (1.17e-3)" "potential prognostic unfavorable (1.90e-4)" "unprognostic (1.56e-2)" "unprognostic (2.22e-2)" "unprognostic (1.89e-2)" "unprognostic (2.34e-1)" "unprognostic (1.11e-1)" "unprognostic (4.49e-1)" "unprognostic (7.24e-2)" "potential prognostic favorable (1.67e-8)" "unprognostic (1.26e-1)" "unprognostic (1.23e-3)" "unprognostic (9.21e-2)" "unprognostic (4.74e-2)" "unprognostic (5.88e-2)" "unprognostic (4.00e-1)" "unprognostic (2.85e-1)" "unprognostic (1.85e-1)" "unprognostic (1.47e-3)" "unprognostic (8.99e-3)" "unprognostic (2.49e-1)" "unprognostic (1.49e-2)" "unprognostic (2.26e-1)" "unprognostic (2.77e-3)" "potential prognostic favorable (2.99e-4)" "unprognostic (1.03e-1)" "unprognostic (1.84e-1)" "unprognostic (4.35e-1)" "unprognostic (8.97e-2)" "unprognostic (7.29e-2)" PEX5 "PTS1R, PXR1" ENSG00000139197 "Peroxisomal biogenesis factor 5" P50542 12 7188685-7218574 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Translocation, Transport" "Disease variant, Peroxisome biogenesis disorder, Rhizomelic chondrodysplasia punctata, Zellweger syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Early spermatids: 244.4;Late primary spermatocytes: 64.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039259, HPA039260" Enhanced Supported "Golgi apparatus,Cytosol" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 48 "Golgi apparatus, Cytosol" "HPA039259: , HPA039260: " "unprognostic (5.02e-2)" "unprognostic (5.18e-2)" "unprognostic (6.22e-2)" "unprognostic (1.12e-2)" "unprognostic (2.84e-1)" "unprognostic (1.15e-1)" "unprognostic (3.32e-1)" "unprognostic (3.65e-2)" "unprognostic (1.42e-1)" "unprognostic (1.80e-3)" "potential prognostic favorable (1.23e-6)" "unprognostic (3.20e-2)" "unprognostic (2.16e-1)" "unprognostic (1.83e-1)" "unprognostic (1.28e-3)" "unprognostic (6.13e-3)" "unprognostic (3.61e-2)" "unprognostic (3.73e-1)" "unprognostic (5.15e-1)" "unprognostic (1.86e-2)" "unprognostic (2.38e-1)" "unprognostic (5.01e-2)" "unprognostic (3.79e-2)" "unprognostic (2.55e-1)" "unprognostic (4.31e-3)" "unprognostic (3.88e-2)" "unprognostic (3.45e-2)" "unprognostic (2.90e-2)" "unprognostic (1.06e-1)" "unprognostic (1.78e-2)" "unprognostic (2.93e-1)" PEX5L "PEX5R, PXR2, TRIP8b" ENSG00000114757 "Peroxisomal biogenesis factor 5 like" Q8IYB4 3 179794958-180037053 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 46.5;parathyroid gland: 28.4;retina: 14.1" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 638.1;Cone photoreceptor cells: 2577.3;Corticotrophs: 2463.9;Gonadotrophs: 386.6;Lactotrophs: 437.3;Oligodendrocytes: 2214.1;Retinal amacrine cells: 372.7;Retinal ganglion cells: 521.5;Somatotrophs: 556.0;Thyrotrophs: 426.5" "Cell type enhanced" "Detected in all" "hippocampal CA1-3: 2571.4;oligodendrocyte: 3240.2" "Cancer enhanced" "Detected in some" "Breast Invasive Carcinoma (TCGA): 1.9;Glioblastoma Multiforme (TCGA): 2.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "lung cancer: 6.7" "Adipose visceral - Mesothelial cells, Pituitary gland - Corticotropes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058026 Enhanced NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 80: Oligodendrocytes - Myelination" "HPA058026: " "unprognostic (4.30e-2)" "unprognostic (2.98e-1)" "unprognostic (2.84e-1)" "unprognostic (5.13e-2)" "unprognostic (8.75e-3)" "unprognostic (9.27e-2)" PEX6 "PAF-2, PXAAA1" ENSG00000124587 "Peroxisomal biogenesis factor 6" Q13608 6 42963865-42979181 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Peroxisome biogenesis" Hydrolase "Amelogenesis imperfecta, Deafness, Disease variant, Peroxisome biogenesis disorder, Zellweger syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 71.9" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025924 Supported Approved "Golgi apparatus,Cytosol" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 70: Non-specific - Protein processing" "Cluster 18: Non-specific - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 23 "Golgi apparatus" Cytosol "HPA025924: " "unprognostic (2.85e-2)" "unprognostic (3.39e-2)" "unprognostic (4.76e-2)" "unprognostic (5.60e-2)" "unprognostic (1.06e-1)" "unprognostic (1.44e-3)" "unprognostic (1.07e-1)" "unprognostic (1.32e-1)" "unprognostic (4.31e-1)" "unprognostic (4.02e-1)" "unprognostic (2.77e-1)" "unprognostic (1.51e-2)" "unprognostic (3.99e-1)" "unprognostic (6.78e-2)" "unprognostic (3.70e-2)" "unprognostic (2.50e-2)" "unprognostic (9.34e-2)" "unprognostic (9.70e-2)" "unprognostic (2.16e-1)" "unprognostic (1.22e-1)" "unprognostic (4.41e-1)" "potential prognostic favorable (7.58e-4)" "unprognostic (3.91e-2)" "unprognostic (4.13e-1)" "unprognostic (2.00e-2)" "unprognostic (2.97e-1)" "unprognostic (3.83e-2)" "unprognostic (7.69e-2)" "unprognostic (2.68e-1)" "unprognostic (2.52e-1)" "unprognostic (2.93e-1)" PEX7 "PTS2R, RD" ENSG00000112357 "Peroxisomal biogenesis factor 7" O00628 6 136822564-136913934 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Cataract, Deafness, Disease variant, Ichthyosis, Peroxisome biogenesis disorder, Retinitis pigmentosa, Rhizomelic chondrodysplasia punctata" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Parietal cells: 164.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Minor Salivary Gland - Minor salivary glandular cells, Stomach - Parietal cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049202 Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 97: Non-specific - Cellular respiration" 24 "Nucleoplasm, Vesicles" "HPA049202: " "unprognostic (1.94e-2)" "unprognostic (2.08e-3)" "unprognostic (5.87e-2)" "unprognostic (3.56e-3)" "unprognostic (3.50e-3)" "unprognostic (8.87e-2)" "unprognostic (1.05e-1)" "unprognostic (5.86e-2)" "unprognostic (2.32e-2)" "unprognostic (1.46e-1)" "potential prognostic favorable (1.40e-8)" "unprognostic (9.42e-3)" "unprognostic (5.41e-3)" "unprognostic (1.56e-1)" "unprognostic (1.49e-3)" "unprognostic (2.46e-3)" "unprognostic (4.40e-1)" "unprognostic (7.04e-2)" "unprognostic (3.84e-1)" "unprognostic (3.68e-2)" "unprognostic (1.14e-2)" "unprognostic (2.04e-1)" "unprognostic (4.13e-1)" "unprognostic (1.87e-1)" "unprognostic (3.36e-3)" "unprognostic (4.66e-2)" "unprognostic (3.10e-2)" "unprognostic (3.04e-1)" "unprognostic (1.23e-1)" "unprognostic (4.68e-1)" "unprognostic (1.23e-1)" PF4 "CXCL4, SCYB4" ENSG00000163737 "Platelet factor 4" P02776 4 73980811-73982027 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" Chemotaxis "Cytokine, Heparin-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 28.0;lymphoid tissue: 9.8" "Group enriched" "Detected in some" 24 "Megakaryocytes: 939.6;Platelets: 1436.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Colon Adenocarcinoma (TCGA): 5.0;Pancreatic Adenocarcinoma (TCGA): 1.8;Rectum Adenocarcinoma (TCGA): 3.0;Stomach Adenocarcinoma (TCGA): 3.0" "Region enhanced" "Detected in single" "cerebral cortex: 1.9" "Immune cell enriched" "Detected in single" 5 "neutrophil: 2.0" "Lineage enriched" "Detected in single" 9 "granulocytes: 2.0" "Not detected" "Not detected" "Minor Salivary Gland - Minor salivary glandular cells" "CAB026008, HPA052485" Enhanced "Secreted to blood" Cytokine NA NA 7700000 2800000000 "Cluster 4: Neutrophils - Degranulation" "Cluster 15: Bone marrow - Innate immune response" "Cluster 23: Choroid plexus - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 47: Platelets - Hemostasis" 22 "CAB026008: , HPA052485: " "unprognostic (8.32e-2)" "unprognostic (1.33e-2)" "unprognostic (2.12e-2)" "unprognostic (2.83e-2)" "unprognostic (2.69e-1)" "unprognostic (2.05e-2)" "unprognostic (1.54e-1)" "unprognostic (2.69e-1)" PF4V1 "CXCL4L1, CXCL4V1, SCYB4V1" ENSG00000109272 "Platelet factor 4 variant 1" P10720 4 73853296-73854483 "Plasma proteins, Predicted secreted proteins" "Cytokine, Heparin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 1.6;lymphoid tissue: 2.7" "Group enriched" "Detected in some" 70 "Megakaryocytes: 544.0;Platelets: 2136.8" "Cell type enhanced" "Detected in single" "fibroblast: 1.8" "Group enriched" "Detected in some" 4 "Kidney Renal Clear Cell Carcinoma (TCGA): 4.1;Kidney Renal Papillary Cell Carcinoma (TCGA): 6.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 42 "basophil: 12.5;neutrophil: 9.2" "Lineage enriched" "Detected in single" 48 "granulocytes: 12.5" "Cancer enhanced" "Detected in single" "thyroid cancer: 1.2" HPA052485 Supported "Secreted to blood" Cytokine NA NA 1500000000 "Cluster 4: Neutrophils - Degranulation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 47: Platelets - Hemostasis" 1 "HPA052485: " "unprognostic (8.28e-3)" "unprognostic (4.80e-3)" "unprognostic (1.80e-3)" "unprognostic (1.35e-2)" "unprognostic (9.26e-3)" "unprognostic (3.97e-1)" "unprognostic (1.03e-2)" PFAS "FGARAT, GATD8, KIAA0361, PURL" ENSG00000178921 "Phosphoribosylformylglycinamidine synthase" O15067 17 8247618-8270491 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Purine biosynthesis" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 39.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 49.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022140, HPA022886" Enhanced Approved Vesicles NA NA 620000 "Cluster 35: Neutrophils - Protein binding" "Cluster 64: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 44: Plasma cells - Antibody production & secretion" 8 Vesicles "HPA022140: , HPA022886: " "unprognostic (2.23e-1)" "unprognostic (7.65e-2)" "unprognostic (3.97e-1)" "unprognostic (8.86e-3)" "unprognostic (1.65e-1)" "unprognostic (4.24e-2)" "unprognostic (2.75e-1)" "potential prognostic favorable (1.90e-4)" "unprognostic (5.26e-2)" "unprognostic (1.68e-2)" "unprognostic (5.15e-3)" "unprognostic (1.69e-2)" "unprognostic (8.11e-2)" "potential prognostic unfavorable (2.72e-6)" "unprognostic (4.59e-2)" "unprognostic (1.20e-1)" "unprognostic (3.88e-2)" "unprognostic (4.25e-1)" "unprognostic (2.29e-2)" "unprognostic (1.76e-1)" "unprognostic (6.38e-2)" "potential prognostic favorable (8.84e-4)" "unprognostic (3.64e-1)" "potential prognostic unfavorable (3.73e-4)" "unprognostic (1.19e-2)" "unprognostic (8.61e-2)" "unprognostic (9.10e-3)" "unprognostic (1.08e-1)" "unprognostic (1.20e-1)" "unprognostic (4.80e-2)" "unprognostic (8.71e-3)" PFDN1 PFD1 ENSG00000113068 "Prefoldin subunit 1" O60925 5 140245035-140303113 "Essential proteins, Predicted intracellular proteins, Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 31 "Epicardial cells: 6008.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006499 Approved Approved "Nucleoli,Plasma membrane,Cytosol" NA NA 20000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 45: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 58 "Plasma membrane, Cytosol" Nucleoli "HPA006499: " "unprognostic (8.06e-2)" "unprognostic (4.85e-2)" "unprognostic (1.87e-2)" "unprognostic (1.07e-2)" "unprognostic (1.44e-1)" "unprognostic (3.79e-1)" "unprognostic (1.96e-2)" "unprognostic (3.18e-2)" "potential prognostic unfavorable (3.45e-4)" "unprognostic (3.96e-2)" "potential prognostic favorable (4.05e-5)" "unprognostic (3.44e-2)" "unprognostic (8.53e-2)" "potential prognostic unfavorable (1.03e-5)" "unprognostic (8.57e-3)" "potential prognostic unfavorable (1.49e-4)" "unprognostic (7.18e-2)" "unprognostic (1.57e-1)" "unprognostic (1.64e-2)" "unprognostic (2.14e-1)" "unprognostic (1.45e-1)" "unprognostic (1.62e-2)" "potential prognostic unfavorable (1.13e-4)" "unprognostic (9.20e-2)" "unprognostic (2.99e-1)" "unprognostic (1.28e-1)" "unprognostic (3.64e-1)" "unprognostic (2.48e-2)" "unprognostic (1.79e-1)" "unprognostic (3.05e-1)" "unprognostic (5.97e-2)" PFDN2 ENSG00000143256 "Prefoldin subunit 2" Q9UHV9 1 161100556-161118055 "Essential proteins, Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 494.5;Oocytes: 1344.7;Suprabasal keratinocytes: 474.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028296, HPA028700" Approved Supported Nucleoplasm,Mitochondria,Cytosol NA NA 85000 "Cluster 29: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 127 "Nucleoplasm, Mitochondria" Cytosol "HPA028296: , HPA028700: " "unprognostic (2.38e-3)" "unprognostic (1.92e-1)" "unprognostic (2.36e-1)" "unprognostic (1.72e-2)" "unprognostic (2.80e-2)" "unprognostic (3.38e-2)" "unprognostic (2.10e-2)" "unprognostic (1.50e-1)" "unprognostic (1.60e-3)" "unprognostic (8.49e-2)" "validated prognostic unfavorable (3.33e-7)" "validated prognostic unfavorable (5.41e-4)" "potential prognostic unfavorable (2.92e-10)" "potential prognostic unfavorable (4.54e-4)" "unprognostic (6.97e-2)" "unprognostic (5.60e-3)" "potential prognostic unfavorable (4.14e-4)" "unprognostic (3.51e-2)" "unprognostic (5.48e-1)" "unprognostic (2.58e-2)" "unprognostic (1.95e-1)" "unprognostic (6.35e-2)" "unprognostic (1.42e-2)" "unprognostic (4.81e-2)" "unprognostic (2.65e-2)" "unprognostic (8.10e-2)" "unprognostic (5.01e-3)" "unprognostic (5.88e-2)" "unprognostic (1.53e-1)" "unprognostic (3.12e-1)" "unprognostic (6.98e-2)" PFDN4 "C-1, C1, PFD4" ENSG00000101132 "Prefoldin subunit 4" Q9NQP4 20 54208087-54228052 "Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric progenitor cells: 355.0;Late primary spermatocytes: 409.5;Oocytes: 331.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA024055 Approved NA NA 430000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 1: Neurons - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 97: Non-specific - Cellular respiration" 45 "HPA024055: " "unprognostic (1.13e-1)" "unprognostic (8.92e-2)" "unprognostic (2.43e-1)" "unprognostic (4.56e-2)" "unprognostic (5.47e-2)" "unprognostic (1.72e-1)" "unprognostic (3.10e-2)" "unprognostic (2.15e-1)" "unprognostic (4.15e-2)" "unprognostic (2.34e-2)" "unprognostic (1.40e-3)" "unprognostic (9.03e-3)" "unprognostic (2.67e-2)" "validated prognostic unfavorable (1.19e-6)" "validated prognostic unfavorable (3.31e-6)" "unprognostic (2.00e-2)" "unprognostic (1.61e-2)" "unprognostic (1.56e-1)" "unprognostic (2.74e-1)" "unprognostic (2.21e-1)" "unprognostic (1.20e-2)" "unprognostic (1.23e-1)" "potential prognostic unfavorable (4.30e-8)" "unprognostic (3.56e-1)" "unprognostic (2.08e-1)" "unprognostic (2.77e-2)" "unprognostic (3.97e-1)" "unprognostic (1.86e-1)" "unprognostic (2.40e-1)" "unprognostic (4.97e-2)" "unprognostic (2.18e-2)" PFDN5 "MM-1, PFD5" ENSG00000123349 "Prefoldin subunit 5" Q99471 12 53295291-53299452 "Essential proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 49.0;Bergmann glia: 44.7;Brain excitatory neurons: 50.9;Brain inhibitory neurons: 48.1;Choroid plexus epithelial cells: 31.4;Distal convoluted tubule cells: 27.0;Ependymal cells: 46.3;Loop of henle epithelial cells: 39.2;Microglia: 46.8;Oligodendrocyte progenitor cells: 32.8;Oligodendrocytes: 49.2;Other brain neurons: 49.1;Papillary tip epithelial cells: 62.2;Proximal tubule cells: 34.6;Renal collecting duct intercalated cells: 31.9;Renal collecting duct principal cells: 52.7;Renal connecting tubule cells: 30.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008587 Approved Supported "Intermediate filaments,Cytosol" NA NA 95000 "Cluster 18: Non-specific - Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 98: Neurons - Neurotransmission & signaling" 134 "Intermediate filaments, Cytosol" "HPA008587: " "unprognostic (4.12e-3)" "unprognostic (2.34e-3)" "unprognostic (3.88e-2)" "unprognostic (1.56e-2)" "unprognostic (1.25e-1)" "unprognostic (1.45e-1)" "unprognostic (4.82e-1)" "unprognostic (2.52e-2)" "unprognostic (2.96e-1)" "unprognostic (2.81e-2)" "unprognostic (1.22e-1)" "unprognostic (2.07e-1)" "unprognostic (1.43e-1)" "potential prognostic unfavorable (3.75e-4)" "unprognostic (1.02e-3)" "unprognostic (2.25e-1)" "unprognostic (8.36e-2)" "unprognostic (1.01e-1)" "unprognostic (2.64e-2)" "unprognostic (3.65e-2)" "unprognostic (1.59e-2)" "unprognostic (3.04e-3)" "unprognostic (5.86e-2)" "unprognostic (5.52e-2)" "unprognostic (5.08e-2)" "unprognostic (7.91e-2)" "unprognostic (1.26e-1)" "unprognostic (9.86e-3)" "unprognostic (2.93e-1)" "unprognostic (7.34e-2)" "unprognostic (6.39e-2)" PFDN6 "H2-KE2, HKE2, KE-2, PFD6" ENSG00000204220 "Prefoldin subunit 6" O15212 6 33289302-33298401 "Essential proteins, Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 131.1;Late primary spermatocytes: 192.8;Oocytes: 244.1" "Cell type enhanced" "Detected in all" "ependymal cell: 85.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043032, HPA048123" Enhanced Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 130000 "Cluster 30: Non-specific - DNA binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 81 "Nucleoplasm, Golgi apparatus" Cytosol "HPA043032: , HPA048123: " "unprognostic (6.68e-2)" "unprognostic (9.97e-2)" "unprognostic (2.56e-2)" "unprognostic (1.44e-1)" "unprognostic (1.12e-1)" "unprognostic (4.48e-2)" "unprognostic (6.64e-2)" "unprognostic (2.83e-1)" "unprognostic (9.80e-3)" "unprognostic (4.17e-2)" "potential prognostic unfavorable (1.94e-4)" "unprognostic (5.90e-3)" "unprognostic (9.38e-2)" "unprognostic (1.43e-2)" "unprognostic (3.19e-3)" "unprognostic (2.21e-2)" "unprognostic (3.49e-2)" "unprognostic (5.84e-2)" "unprognostic (4.96e-2)" "potential prognostic favorable (2.20e-4)" "unprognostic (2.37e-1)" "unprognostic (5.90e-2)" "unprognostic (1.94e-1)" "unprognostic (4.49e-2)" "unprognostic (9.68e-2)" "unprognostic (4.03e-2)" "unprognostic (9.51e-2)" "unprognostic (1.21e-1)" "unprognostic (3.59e-1)" "unprognostic (7.20e-3)" "unprognostic (1.11e-1)" PFKFB1 PFRX ENSG00000158571 "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1" P16118 X 54932961-54998534 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Kinase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "adipose tissue: 26.6;liver: 49.7;skeletal muscle: 104.5;tongue: 38.0" "Group enriched" "Detected in many" 6 "Adipocytes: 337.5;Hepatocytes: 97.2;Myonuclei: 241.7" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in some" 9 "Liver Hepatocellular Carcinoma (TCGA): 11.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Skin - Adipocytes (Skin)" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 89: Adipocytes - Lipid metabolism" 13 "unprognostic (2.87e-1)" "unprognostic (6.99e-2)" "unprognostic (2.76e-2)" "unprognostic (1.17e-3)" "potential prognostic favorable (1.26e-4)" PFKFB2 ENSG00000123836 "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2" O60825 1 207034366-207081024 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Kinase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 77.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 199.7;Choroid plexus epithelial cells: 175.3;Esophageal apical cells: 169.2;Late spermatids: 344.8;Neutrophil progenitors: 247.2;Neutrophils: 308.7;Proximal tubule cells: 173.6;Retinal pigment epithelial cells: 162.0;Rod photoreceptor cells: 174.6" "Cell type enhanced" "Detected in all" "astrocyte: 134.6;choroid plexus epithelial cell: 176.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "eosinophil: 20.8;plasmacytoid DC: 23.8" "Group enriched" "Detected in many" 8 "dendritic cells: 23.8;granulocytes: 20.8" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049975, HPA063575" Uncertain Enhanced Nucleoplasm NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 3: Choroid plexus - Cilium" "Cluster 7: Liver cancer - Metabolism" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 21 Nucleoplasm "HPA049975: , HPA063575: " "unprognostic (3.19e-1)" "unprognostic (8.42e-2)" "unprognostic (1.28e-1)" "unprognostic (1.92e-1)" "unprognostic (1.37e-1)" "unprognostic (1.28e-1)" "unprognostic (2.96e-1)" "unprognostic (4.29e-2)" "unprognostic (7.59e-2)" "unprognostic (3.64e-3)" "unprognostic (3.57e-2)" "unprognostic (3.47e-1)" "unprognostic (9.35e-3)" "unprognostic (1.83e-2)" "unprognostic (2.65e-2)" "unprognostic (3.80e-1)" "unprognostic (1.74e-1)" "unprognostic (1.56e-2)" "unprognostic (1.04e-2)" "unprognostic (2.03e-2)" "potential prognostic unfavorable (4.85e-5)" "unprognostic (4.80e-2)" "unprognostic (1.62e-2)" "unprognostic (2.74e-1)" "unprognostic (1.98e-1)" "unprognostic (1.90e-3)" "unprognostic (8.65e-2)" "unprognostic (3.26e-2)" "unprognostic (1.62e-1)" "potential prognostic unfavorable (2.23e-4)" "unprognostic (1.15e-1)" PFKFB3 ENSG00000170525 "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3" Q16875 10 6144934-6254644 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Kinase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 314.1;skeletal muscle: 534.6" "Cell type enriched" "Detected in many" 4 "Neutrophils: 3062.7" "Cell type enhanced" "Detected in all" "astrocyte: 401.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 26.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008266, CAB020795, HPA043889" Uncertain Enhanced Nucleoplasm NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 4 Nucleoplasm "CAB020795: , HPA008266: , HPA043889: " "unprognostic (3.48e-2)" "unprognostic (1.23e-1)" "unprognostic (2.08e-2)" "unprognostic (2.35e-3)" "unprognostic (6.80e-2)" "unprognostic (2.36e-1)" "unprognostic (3.46e-1)" "unprognostic (2.57e-2)" "unprognostic (3.92e-2)" "unprognostic (6.79e-3)" "unprognostic (2.68e-3)" "unprognostic (2.52e-1)" "unprognostic (3.41e-3)" "unprognostic (1.26e-2)" "unprognostic (2.59e-1)" "unprognostic (6.09e-2)" "unprognostic (2.88e-3)" "unprognostic (5.33e-2)" "unprognostic (1.26e-1)" "unprognostic (1.03e-1)" "potential prognostic unfavorable (1.81e-8)" "unprognostic (1.49e-1)" "unprognostic (4.93e-3)" "unprognostic (1.12e-1)" "unprognostic (1.83e-1)" "unprognostic (3.29e-2)" "unprognostic (1.27e-1)" "unprognostic (1.45e-2)" "unprognostic (9.39e-2)" "unprognostic (2.13e-1)" "unprognostic (1.03e-1)" PFKFB4 ENSG00000114268 "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4" Q16877 3 48517684-48562015 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Kinase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 23.8" "Cell type enhanced" "Detected in many" "Enterocytes: 112.4;Epididymal basal cells: 81.8;Extravillous trophoblasts: 104.9;Neutrophil progenitors: 102.2;Neutrophils: 248.6;Retinal ganglion cells: 65.7;Sertoli cells: 177.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 12.6;eosinophil: 22.0;intermediate monocyte: 13.8;neutrophil: 40.6;non-classical monocyte: 25.2" "Group enriched" "Detected in many" 6 "granulocytes: 40.6;monocytes: 25.2" "Cancer enhanced" "Detected in all" "skin cancer: 60.4" "Lung - Neutrophils_2, Spleen - Neutrophils_2, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047719, HPA066058" Uncertain Approved Nucleoli NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 47: Testis - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 69: Skin cancer - ECM organization" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 16 Nucleoli "HPA047719: , HPA066058: " "unprognostic (1.75e-1)" "unprognostic (1.22e-1)" "unprognostic (8.82e-2)" "potential prognostic unfavorable (7.92e-4)" "unprognostic (1.22e-1)" "unprognostic (2.42e-1)" "unprognostic (1.64e-3)" "unprognostic (3.22e-3)" "unprognostic (2.53e-2)" "unprognostic (5.71e-3)" "unprognostic (1.99e-1)" "unprognostic (1.29e-2)" "unprognostic (1.83e-2)" "potential prognostic unfavorable (2.53e-7)" "unprognostic (3.00e-3)" "unprognostic (1.94e-1)" "potential prognostic unfavorable (8.84e-4)" "unprognostic (2.67e-2)" "unprognostic (1.33e-1)" "unprognostic (1.27e-1)" "unprognostic (4.74e-1)" "unprognostic (3.19e-2)" "potential prognostic unfavorable (2.51e-4)" "unprognostic (1.58e-1)" "unprognostic (2.23e-1)" "unprognostic (1.86e-1)" "unprognostic (2.93e-1)" "unprognostic (2.30e-1)" "unprognostic (1.28e-1)" "potential prognostic unfavorable (6.05e-4)" "unprognostic (3.89e-1)" PFKL ENSG00000141959 "Phosphofructokinase, liver type" P17858 21 44300051-44327376 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 234.9;Enterocytes: 317.3;Esophageal apical cells: 293.4;Extravillous trophoblasts: 229.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030047 Approved Uncertain Nucleoli,Mitochondria NA NA 740000 "Cluster 33: Non-specific - ATP binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 65: Non-specific - Cell growth & division" 29 "Nucleoli, Mitochondria" "HPA030047: " "unprognostic (3.06e-1)" "unprognostic (6.71e-3)" "unprognostic (3.38e-1)" "unprognostic (3.90e-2)" "unprognostic (2.72e-1)" "unprognostic (3.51e-2)" "unprognostic (1.19e-1)" "unprognostic (2.71e-1)" "unprognostic (2.68e-1)" "unprognostic (6.22e-2)" "potential prognostic favorable (3.38e-6)" "unprognostic (1.47e-2)" "unprognostic (1.72e-1)" "unprognostic (8.81e-3)" "unprognostic (3.22e-2)" "unprognostic (2.55e-2)" "unprognostic (1.72e-1)" "unprognostic (5.34e-2)" "unprognostic (2.14e-1)" "unprognostic (4.25e-3)" "unprognostic (4.03e-1)" "unprognostic (6.90e-2)" "unprognostic (4.78e-3)" "unprognostic (7.21e-2)" "unprognostic (2.76e-2)" "unprognostic (2.16e-1)" "unprognostic (3.82e-1)" "unprognostic (4.79e-1)" "unprognostic (2.92e-1)" "unprognostic (1.44e-1)" "unprognostic (6.25e-2)" PFKM "PFK-1, PFKX, PPP1R122" ENSG00000152556 "Phosphofructokinase, muscle" P08237 12 48105139-48146404 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "skeletal muscle: 1472.3;tongue: 1300.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 239.5;Late primary spermatocytes: 94.5;Müller glia: 114.9;Myonuclei: 175.1;Thymic myoid cells: 407.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Minor Salivary Gland - Endothelial cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002117 Approved Approved "Endoplasmic reticulum,Principal piece" NA NA 240000 "Cluster 29: Non-specific - Unknown function" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 15 "Endoplasmic reticulum" "Principal piece" "HPA002117: " "unprognostic (1.18e-1)" "unprognostic (5.58e-3)" "unprognostic (2.83e-1)" "unprognostic (6.97e-3)" "unprognostic (2.78e-1)" "unprognostic (2.42e-2)" "unprognostic (2.76e-1)" "unprognostic (4.73e-3)" "potential prognostic unfavorable (6.74e-4)" "unprognostic (5.66e-3)" "potential prognostic favorable (1.44e-8)" "unprognostic (6.92e-2)" "unprognostic (1.29e-3)" "unprognostic (2.19e-2)" "potential prognostic unfavorable (8.47e-4)" "unprognostic (2.71e-2)" "unprognostic (1.36e-1)" "unprognostic (3.22e-1)" "unprognostic (8.52e-2)" "unprognostic (1.06e-1)" "unprognostic (1.17e-1)" "unprognostic (2.73e-2)" "unprognostic (2.49e-2)" "unprognostic (3.34e-2)" "unprognostic (1.23e-1)" "unprognostic (3.55e-1)" "unprognostic (3.31e-1)" "unprognostic (1.94e-1)" "unprognostic (6.91e-2)" "unprognostic (5.13e-2)" "unprognostic (8.43e-2)" PFKP "PFK-C, PFKF" ENSG00000067057 "Phosphofructokinase, platelet" Q01813 10 3066333-3137718 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 250.0" "Cell type enhanced" "Detected in many" "Early spermatids: 202.0;Late primary spermatocytes: 241.3;Late spermatids: 287.5;Müller glia: 186.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018257, HPA056484" Uncertain Supported Cytosol No No 1400000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 51: Secretory epithelial cells - Mixed function" 45 Cytosol "HPA018257: , HPA056484: " "unprognostic (3.65e-2)" "unprognostic (1.38e-1)" "unprognostic (6.80e-2)" "unprognostic (5.20e-3)" "unprognostic (2.09e-1)" "unprognostic (2.12e-1)" "unprognostic (1.51e-1)" "unprognostic (1.27e-2)" "potential prognostic unfavorable (1.42e-4)" "unprognostic (1.46e-3)" "potential prognostic favorable (1.09e-6)" "unprognostic (6.00e-2)" "unprognostic (8.11e-2)" "potential prognostic unfavorable (3.15e-5)" "unprognostic (3.11e-1)" "potential prognostic unfavorable (2.00e-5)" "unprognostic (2.79e-2)" "unprognostic (6.67e-2)" "unprognostic (1.52e-1)" "unprognostic (9.97e-2)" "unprognostic (1.40e-1)" "unprognostic (1.12e-2)" "unprognostic (1.79e-2)" "unprognostic (1.96e-2)" "unprognostic (2.14e-1)" "unprognostic (1.25e-1)" "unprognostic (1.41e-1)" "unprognostic (5.16e-2)" "unprognostic (2.53e-1)" "unprognostic (2.44e-1)" "unprognostic (1.56e-1)" PFN1 ENSG00000108518 "Profilin 1" P07737 17 4945652-4949061 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 6865.5;Hofbauer cells: 4932.2;Megakaryocytes: 4642.4;Migrating cytotrophoblasts: 3040.8" "Cell type enhanced" "Detected in all" "leukocyte: 353.3;vascular associated smooth muscle cell: 221.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "CAB037134, CAB037140" Enhanced Approved Cytosol NA NA 590000000 "Cluster 29: Non-specific - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 27: Non-specific - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 85 Cytosol "CAB037134: , CAB037140: " "unprognostic (4.73e-3)" "unprognostic (3.61e-2)" "unprognostic (2.39e-1)" "unprognostic (8.41e-2)" "unprognostic (2.03e-1)" "unprognostic (5.66e-2)" "unprognostic (5.06e-2)" "unprognostic (1.60e-1)" "unprognostic (8.20e-3)" "unprognostic (2.76e-3)" "potential prognostic unfavorable (5.19e-4)" "unprognostic (7.37e-2)" "unprognostic (1.85e-1)" "potential prognostic unfavorable (4.47e-4)" "unprognostic (2.17e-2)" "potential prognostic unfavorable (2.84e-4)" "unprognostic (2.99e-3)" "unprognostic (1.47e-1)" "unprognostic (1.88e-3)" "unprognostic (1.33e-2)" "unprognostic (1.33e-1)" "unprognostic (2.20e-1)" "unprognostic (2.04e-1)" "unprognostic (4.17e-2)" "unprognostic (8.85e-2)" "unprognostic (7.11e-2)" "unprognostic (1.11e-1)" "unprognostic (2.40e-2)" "unprognostic (2.10e-2)" "unprognostic (1.07e-1)" "unprognostic (1.64e-1)" PFN2 ENSG00000070087 "Profilin 2" P35080 3 149964904-150050788 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 341.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 63.0;Early spermatids: 31.9;Epicardial cells: 29.6;Late primary spermatocytes: 24.6;Myonuclei: 71.0;Undifferentiated spermatogonia: 26.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035611, CAB037073" Enhanced NA NA 61000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 51: Neurons - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 25 "CAB037073: , HPA035611: " "unprognostic (3.15e-1)" "unprognostic (6.77e-2)" "unprognostic (1.27e-2)" "unprognostic (2.03e-1)" "unprognostic (3.04e-1)" "unprognostic (2.77e-1)" "unprognostic (1.22e-2)" "potential prognostic favorable (7.06e-4)" "unprognostic (2.87e-3)" "unprognostic (1.23e-1)" "unprognostic (1.23e-1)" "unprognostic (4.17e-2)" "unprognostic (2.37e-2)" "validated prognostic unfavorable (1.00e-7)" "validated prognostic unfavorable (9.46e-4)" "unprognostic (1.73e-3)" "unprognostic (7.06e-2)" "unprognostic (8.07e-3)" "unprognostic (7.67e-2)" "unprognostic (4.82e-2)" "unprognostic (2.38e-1)" "unprognostic (2.71e-3)" "unprognostic (1.35e-2)" "unprognostic (2.15e-2)" "unprognostic (8.30e-2)" "unprognostic (2.33e-1)" "unprognostic (2.82e-1)" "unprognostic (8.41e-3)" "unprognostic (1.03e-1)" "unprognostic (8.18e-2)" "unprognostic (1.14e-1)" PFN3 ENSG00000196570 "Profilin 3" P60673 5 177400109-177400661 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 27 "testis: 24.0" "Group enriched" "Detected in some" 14 "Early spermatids: 846.7;Late spermatids: 2308.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA038274 Uncertain Vesicles,Cytosol NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 7 "Vesicles, Cytosol" "HPA038274: " PFN4 ENSG00000176732 "Profilin family member 4" Q8NHR9 2 24114809-24123464 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 25 "testis: 77.5" "Group enriched" "Detected in many" 12 "Early spermatids: 476.9;Late primary spermatocytes: 1354.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Not detected" "Not detected" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 9: Non-specific - Receptor signaling" "Cluster 4: Non-specific - Transcription" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" "unprognostic (1.47e-3)" "unprognostic (5.59e-2)" "unprognostic (1.51e-2)" "unprognostic (3.52e-2)" "unprognostic (5.48e-2)" "validated prognostic unfavorable (3.58e-6)" "validated prognostic unfavorable (3.87e-4)" "unprognostic (2.52e-1)" "unprognostic (1.71e-2)" "unprognostic (8.71e-3)" "unprognostic (8.91e-2)" "unprognostic (2.44e-1)" "unprognostic (8.29e-2)" "unprognostic (3.49e-2)" "unprognostic (1.78e-1)" "unprognostic (7.44e-2)" "unprognostic (1.84e-1)" "unprognostic (1.11e-1)" PGA3 ENSG00000229859 "Pepsinogen A3" P0DJD8 11 61203307-61213098 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 906 "stomach 1: 63357.7" "Cell type enriched" "Detected in some" 4 "Gastric chief cells: 2959.5" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 100 "Stomach Adenocarcinoma (TCGA): 602.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "CAB026358, HPA046875" Enhanced "Secreted to digestive system" Enzyme NA NA "Cluster 60: Stomach - Digestion" "Cluster 29: Forebrain - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 97: Non-specific - Cellular respiration" "CAB026358: , HPA046875: " "unprognostic (1.44e-3)" "unprognostic (9.05e-2)" "unprognostic (6.29e-2)" "unprognostic (1.50e-1)" "unprognostic (7.22e-2)" "unprognostic (8.16e-2)" "unprognostic (5.22e-2)" "unprognostic (3.67e-2)" PGA4 ENSG00000229183 "Pepsinogen A4" P0DJD7 11 61222347-61231694 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 2475 "stomach 1: 131038.6" "Cell type enriched" "Detected in some" 6 "Gastric chief cells: 86.3" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 224 "Stomach Adenocarcinoma (TCGA): 1651.9" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "classical monocyte: 9.9;intermediate monocyte: 10.8;non-classical monocyte: 3.4" "Lineage enriched" "Detected in single" 26 "monocytes: 10.8" "Not detected" "Not detected" "Stomach - Chief cells" HPA046875 Supported "Secreted to digestive system" Enzyme NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 60: Stomach - Digestion" "Cluster 49: HMC-1 - Innate immune response" "Cluster 97: Non-specific - Cellular respiration" 8 "HPA046875: " "unprognostic (7.26e-2)" "potential prognostic favorable (1.43e-4)" "unprognostic (5.14e-2)" "unprognostic (1.09e-1)" "unprognostic (1.27e-1)" "unprognostic (1.70e-1)" "unprognostic (1.11e-1)" "unprognostic (6.08e-2)" PGA5 ENSG00000256713 "Pepsinogen A5" P0DJD9 11 61241175-61251444 "Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Aspartyl protease, Hydrolase, Protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4738 "stomach 1: 35793.5" "Cell type enriched" "Detected in some" 5 "Gastric chief cells: 53221.2" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 33 "Stomach Adenocarcinoma (TCGA): 298.4" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 29 "classical monocyte: 1.8;intermediate monocyte: 4.3;non-classical monocyte: 2.4" "Lineage enriched" "Detected in single" 44 "monocytes: 4.3" "Not detected" "Not detected" "Breast - Adipocytes (Breast), Stomach - Chief cells" HPA046875 Supported "Secreted to digestive system" Enzyme NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 60: Stomach - Digestion" "Cluster 51: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 97: Non-specific - Cellular respiration" "HPA046875: " "unprognostic (3.38e-2)" "unprognostic (4.21e-3)" "unprognostic (1.29e-1)" "unprognostic (2.49e-2)" "unprognostic (9.99e-2)" "unprognostic (1.74e-1)" "unprognostic (4.60e-2)" "unprognostic (1.42e-2)" "unprognostic (2.08e-2)" PGAM1 "PGAM-B, PGAMA" ENSG00000171314 "Phosphoglycerate mutase 1" P18669 10 97426191-97433444 "Candidate cardiovascular disease genes, Enzymes, Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis "Hydrolase, Isomerase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 175.7;Suprabasal keratinocytes: 127.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "HPA042528, HPA060483" Approved Approved "Nucleoplasm,Mid piece" NA NA 33000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 1: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 97: Non-specific - Cellular respiration" 18 Nucleoplasm "Mid piece" "HPA042528: , HPA060483: " "unprognostic (2.50e-3)" "potential prognostic unfavorable (5.65e-4)" "unprognostic (2.89e-1)" "unprognostic (1.67e-2)" "unprognostic (1.40e-1)" "unprognostic (2.02e-1)" "unprognostic (2.45e-1)" "unprognostic (1.50e-1)" "unprognostic (7.00e-3)" "unprognostic (1.62e-1)" "potential prognostic favorable (6.31e-5)" "unprognostic (1.32e-1)" "unprognostic (1.89e-1)" "unprognostic (6.82e-3)" "unprognostic (2.25e-3)" "validated prognostic unfavorable (8.26e-7)" "validated prognostic unfavorable (8.47e-5)" "unprognostic (1.27e-1)" "unprognostic (9.30e-3)" "unprognostic (5.48e-2)" "unprognostic (9.56e-2)" "unprognostic (5.98e-2)" "unprognostic (1.47e-2)" "unprognostic (9.46e-3)" "unprognostic (8.27e-2)" "unprognostic (1.56e-1)" "unprognostic (5.97e-2)" "unprognostic (5.80e-2)" "unprognostic (1.85e-1)" "unprognostic (4.39e-2)" "unprognostic (8.46e-2)" PGAM2 PGAM-M ENSG00000164708 "Phosphoglycerate mutase 2" P15259 7 44062727-44065567 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis "Hydrolase, Isomerase" "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 13 "heart muscle: 1112.4;skeletal muscle: 4078.1;tongue: 1636.7" "Cell type enriched" "Detected in many" 4 "Late spermatids: 3000.2" "Cell type enhanced" "Detected in many" "astrocyte: 17.0;ependymal cell: 15.3;upper rhombic lip: 21.0;vascular associated smooth muscle cell: 13.3" "Cancer enriched" "Detected in many" 4 "Glioblastoma Multiforme (TCGA): 62.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 8.8;thyroid cancer: 14.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA043801, HPA050314, HPA060173" Enhanced Approved Nucleoplasm,Nucleoli,Cytosol NA NA 16000000 "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 19: Astrocytes - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 45 Nucleoplasm "Nucleoli, Cytosol" "HPA043801: , HPA050314: , HPA060173: " "unprognostic (2.07e-1)" "unprognostic (8.87e-2)" "unprognostic (1.18e-1)" "unprognostic (5.17e-3)" "unprognostic (2.17e-1)" "unprognostic (1.38e-2)" "unprognostic (6.74e-2)" "unprognostic (4.38e-2)" "potential prognostic unfavorable (1.85e-5)" "unprognostic (4.34e-1)" "unprognostic (6.63e-2)" "unprognostic (1.62e-1)" "unprognostic (3.25e-2)" "unprognostic (4.11e-2)" "unprognostic (2.68e-2)" "unprognostic (1.59e-1)" "unprognostic (8.66e-2)" "unprognostic (1.04e-2)" "unprognostic (3.24e-2)" "unprognostic (4.19e-2)" "unprognostic (2.84e-2)" "unprognostic (3.10e-2)" "unprognostic (1.24e-1)" "unprognostic (3.58e-2)" PGAM4 "dJ1000K24.1, PGAM-B, PGAM1, PGAM3" ENSG00000226784 "Phosphoglycerate mutase family member 4" Q8N0Y7 X 77967949-77969638 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Glycolysis "Hydrolase, Isomerase" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA042528, HPA060483" Uncertain Approved "Nucleoplasm,Mid piece" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 24: Neurons - Mixed function" "Cluster 61: BICR 18 - Protein kinases" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 21 Nucleoplasm "Mid piece" "HPA042528: , HPA060483: " "unprognostic (3.76e-2)" PGAM5 "BXLBv68, MGC5352" ENSG00000247077 "PGAM family member 5, mitochondrial serine/threonine protein phosphatase" Q96HS1 12 132710819-132722734 "Enzymes, Predicted intracellular proteins" Necrosis Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epicardial cells: 29.6;Late spermatids: 32.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036978, HPA036979, CAB068215" Enhanced Supported Mitochondria "Intracellular and membrane" Enzyme NA NA 9100 "Cluster 5: Non-specific - Cell proliferation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 25 Mitochondria "CAB068215: , HPA036978: , HPA036979: " "unprognostic (6.54e-2)" "unprognostic (4.58e-3)" "unprognostic (4.93e-2)" "unprognostic (4.00e-3)" "unprognostic (4.52e-2)" "unprognostic (3.75e-1)" "unprognostic (3.17e-1)" "unprognostic (2.37e-2)" "unprognostic (2.60e-2)" "unprognostic (3.20e-3)" "unprognostic (2.24e-1)" "unprognostic (1.14e-1)" "unprognostic (2.02e-1)" "validated prognostic unfavorable (7.88e-7)" "validated prognostic unfavorable (4.84e-5)" "unprognostic (1.78e-2)" "unprognostic (1.73e-2)" "unprognostic (2.59e-1)" "unprognostic (1.60e-2)" "unprognostic (1.18e-1)" "unprognostic (3.74e-1)" "unprognostic (5.91e-2)" "unprognostic (1.99e-1)" "unprognostic (1.32e-3)" "unprognostic (2.36e-2)" "unprognostic (3.91e-2)" "unprognostic (8.62e-2)" "unprognostic (1.17e-1)" "unprognostic (3.71e-1)" "unprognostic (8.85e-3)" "unprognostic (1.06e-1)" PGAP1 "Bst1, FLJ12377, SPG67" ENSG00000197121 "Post-GPI attachment to proteins inositol deacylase 1" Q75T13 2 196833004-196927796 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" Hydrolase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Corticotrophs: 429.9;Lactotrophs: 375.0;Somatotrophs: 319.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Lung - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 103: Non-specific - Basic cellular processes" 1 "unprognostic (2.35e-1)" "unprognostic (1.74e-1)" "unprognostic (6.28e-2)" "unprognostic (7.70e-2)" "unprognostic (2.31e-1)" "unprognostic (6.54e-2)" "unprognostic (6.91e-2)" "unprognostic (1.82e-2)" "unprognostic (1.79e-2)" "unprognostic (2.70e-1)" "validated prognostic favorable (9.24e-4)" "validated prognostic favorable (1.16e-4)" "unprognostic (1.78e-2)" "unprognostic (5.44e-3)" "unprognostic (2.50e-1)" "unprognostic (2.53e-2)" "unprognostic (9.92e-3)" "unprognostic (3.14e-3)" "unprognostic (3.07e-2)" "unprognostic (2.66e-1)" "unprognostic (1.73e-3)" "unprognostic (1.22e-1)" "unprognostic (6.33e-2)" "unprognostic (1.48e-1)" "potential prognostic unfavorable (5.32e-4)" "unprognostic (2.56e-2)" "unprognostic (1.60e-1)" "unprognostic (1.47e-1)" "unprognostic (3.94e-2)" "unprognostic (9.46e-2)" PGAP2 "CWH43-N, FRAG1, MRT17, MRT21" ENSG00000148985 "Post-GPI attachment to proteins 2" Q9UHJ9 11 3797724-3826371 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "GPI-anchor biosynthesis" Transferase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "epididymis: 204.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 107.7;Early spermatids: 182.1;Epididymal principal cells: 289.8;Late spermatids: 514.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Kidney - Fibroblasts, Liver - Hepatocytes, Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063099 Approved Approved Microtubules NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 11: White matter - Signal transduction" "Cluster 24: Non-specific - Unknown function" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 4 Microtubules "HPA063099: " "unprognostic (8.61e-2)" "unprognostic (4.56e-2)" "unprognostic (2.10e-1)" "unprognostic (1.06e-1)" "unprognostic (8.17e-3)" "unprognostic (5.13e-2)" "unprognostic (3.01e-3)" "potential prognostic unfavorable (7.14e-5)" "unprognostic (6.63e-2)" "unprognostic (3.09e-2)" "potential prognostic favorable (6.36e-5)" "unprognostic (2.16e-1)" "unprognostic (2.04e-1)" "potential prognostic unfavorable (9.93e-4)" "unprognostic (1.60e-1)" "unprognostic (1.28e-2)" "unprognostic (1.66e-1)" "unprognostic (2.06e-1)" "unprognostic (1.41e-1)" "unprognostic (2.81e-1)" "unprognostic (2.81e-1)" "unprognostic (1.05e-1)" "unprognostic (1.83e-1)" "unprognostic (2.08e-1)" "unprognostic (4.29e-2)" "unprognostic (7.70e-2)" "unprognostic (3.91e-3)" "unprognostic (4.79e-3)" "unprognostic (3.15e-1)" "unprognostic (1.06e-1)" "unprognostic (1.28e-1)" PGAP3 "CAB2, MGC9753, PER1, PERLD1, PP1498" ENSG00000161395 "Post-GPI attachment to proteins phospholipase 3" Q96FM1 17 39671122-39696797 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" Hydrolase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 50.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "breast cancer: 77.4;Esophageal cancer: 77.4" "Adipose subcutaneous - Adipose progenitor cells, Breast - Breast glandular cells, Breast - Breast glandular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016591 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 70: Non-specific - Protein processing" "Cluster 51: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 2 "Plasma membrane, Cytosol" "HPA016591: " "unprognostic (6.35e-2)" "unprognostic (3.09e-1)" "unprognostic (1.30e-2)" "unprognostic (3.95e-2)" "unprognostic (6.54e-2)" "unprognostic (2.48e-1)" "unprognostic (1.69e-1)" "unprognostic (5.10e-2)" "unprognostic (1.32e-1)" "unprognostic (9.89e-2)" "potential prognostic favorable (4.53e-5)" "unprognostic (1.64e-2)" "unprognostic (8.29e-3)" "unprognostic (1.47e-2)" "unprognostic (2.32e-1)" "unprognostic (7.03e-3)" "unprognostic (1.75e-1)" "unprognostic (8.23e-2)" "unprognostic (1.46e-1)" "unprognostic (1.56e-3)" "unprognostic (2.82e-1)" "unprognostic (2.47e-2)" "unprognostic (2.55e-1)" "unprognostic (9.92e-2)" "unprognostic (1.60e-1)" "unprognostic (4.67e-2)" "unprognostic (1.92e-2)" "unprognostic (1.61e-1)" "unprognostic (3.29e-1)" "unprognostic (2.83e-1)" "unprognostic (5.02e-2)" PGAP4 "C9orf125, MGC12992, TMEM246" ENSG00000165152 "Post-GPI attachment to proteins GalNAc transferase 4" Q9BRR3 9 101473170-101533537 "Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 61.3;Tuft cells: 57.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Minor Salivary Gland - Minor salivary gland basal cells, Pituitary gland - Corticotropes, Skin - Keratinocyte (other), Spleen - Fibroblasts_1, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011318, HPA054041, HPA057220" Uncertain Uncertain "Endoplasmic reticulum,Vesicles" NA Yes "Cluster 35: Non-specific - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 98: Neurons - Neurotransmission & signaling" 22 "Endoplasmic reticulum" Vesicles "HPA011318: , HPA054041: , HPA057220: " "unprognostic (1.44e-1)" "unprognostic (1.10e-1)" "unprognostic (2.10e-1)" "potential prognostic unfavorable (1.79e-4)" "unprognostic (1.61e-1)" "potential prognostic favorable (7.29e-5)" "unprognostic (1.37e-1)" "unprognostic (3.51e-1)" "validated prognostic favorable (4.93e-9)" "validated prognostic favorable (9.64e-4)" "potential prognostic favorable (3.14e-5)" "unprognostic (1.46e-3)" "unprognostic (6.55e-2)" "unprognostic (1.43e-2)" "unprognostic (2.68e-1)" "unprognostic (8.44e-2)" "unprognostic (2.97e-1)" "unprognostic (3.55e-2)" "unprognostic (3.16e-2)" "unprognostic (2.05e-2)" "unprognostic (1.42e-1)" "unprognostic (3.37e-3)" "unprognostic (7.20e-2)" "unprognostic (7.53e-2)" "unprognostic (9.84e-2)" "unprognostic (1.49e-1)" "unprognostic (1.70e-1)" "unprognostic (2.26e-3)" PGAP6 "M83, TMEM6, TMEM8, TMEM8A" ENSG00000129925 "Post-GPI attachment to proteins 6" Q9HCN3 16 370788-387113 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 114.1;Epididymal principal cells: 79.9;Esophageal apical cells: 80.0;Late spermatids: 175.3;Syncytiotrophoblasts: 77.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 36.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051281, HPA064673" Approved Supported "Nucleoplasm,Cytokinetic bridge" Yes No "Cluster 4: Neutrophils - Degranulation" "Cluster 8: Pancreas - Proteolysis" "Cluster 12: Non-specific - Vasculature" "Cluster 54: Non-specific - Transcription" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 10 Nucleoplasm "Cytokinetic bridge" "HPA051281: , HPA064673: " "unprognostic (1.69e-1)" "unprognostic (8.30e-2)" "unprognostic (1.27e-3)" "unprognostic (3.50e-2)" "unprognostic (1.72e-1)" "unprognostic (9.81e-2)" "unprognostic (3.50e-1)" "unprognostic (8.44e-2)" "unprognostic (2.09e-3)" "unprognostic (1.24e-2)" "unprognostic (5.21e-2)" "unprognostic (2.00e-2)" "unprognostic (3.24e-3)" "unprognostic (7.24e-2)" "unprognostic (2.96e-1)" "unprognostic (3.48e-3)" "unprognostic (2.00e-1)" "unprognostic (2.14e-1)" "unprognostic (4.79e-2)" "unprognostic (3.58e-1)" "unprognostic (1.37e-2)" "unprognostic (2.86e-2)" "unprognostic (6.58e-2)" "unprognostic (2.99e-1)" "unprognostic (5.22e-1)" "unprognostic (8.04e-3)" "unprognostic (1.28e-1)" "unprognostic (3.75e-2)" "unprognostic (1.19e-1)" PGBD1 "dJ874C20.4, HUCEP-4, SCAND4" ENSG00000137338 "PiggyBac transposable element derived 1" Q96JS3 6 28281572-28302549 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 34.0;Thymocytes: 35.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 1.8;plasmacytoid DC: 1.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Skeletal muscle - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA007267 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 34: Non-specific - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 109: Neurons - Neuronal signaling" 26 Nucleoplasm Cytosol "HPA007267: " "unprognostic (1.06e-1)" "unprognostic (9.27e-2)" "unprognostic (1.67e-1)" "unprognostic (1.15e-1)" "unprognostic (1.34e-1)" "unprognostic (1.35e-1)" "unprognostic (4.16e-2)" "unprognostic (1.38e-3)" "unprognostic (1.75e-1)" "unprognostic (4.25e-2)" "unprognostic (8.70e-3)" "unprognostic (3.32e-2)" "unprognostic (4.47e-1)" "potential prognostic unfavorable (1.40e-4)" "unprognostic (2.40e-1)" "unprognostic (2.26e-1)" "unprognostic (2.60e-1)" "unprognostic (5.57e-2)" "unprognostic (7.20e-3)" "unprognostic (8.67e-2)" "unprognostic (8.49e-2)" "unprognostic (6.01e-3)" "unprognostic (2.37e-3)" "unprognostic (5.36e-3)" "unprognostic (5.23e-2)" "unprognostic (9.67e-2)" "potential prognostic unfavorable (3.42e-4)" "unprognostic (1.45e-2)" "unprognostic (2.78e-1)" "unprognostic (3.74e-2)" "unprognostic (8.95e-2)" PGBD2 ENSG00000185220 "PiggyBac transposable element derived 2" Q6P3X8 1 248906196-248919946 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 38.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in single" "HPA029888, HPA029889, HPA029890" Uncertain Approved Vesicles NA NA "Cluster 32: Basophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 3 Vesicles "HPA029888: , HPA029889: , HPA029890: " "unprognostic (2.46e-1)" "unprognostic (4.86e-1)" "unprognostic (1.13e-1)" "unprognostic (1.42e-1)" "unprognostic (6.48e-2)" "unprognostic (6.92e-2)" "unprognostic (2.27e-1)" "unprognostic (8.61e-3)" "unprognostic (3.02e-3)" "unprognostic (8.87e-2)" "unprognostic (2.38e-2)" "unprognostic (2.60e-2)" "unprognostic (1.54e-1)" "potential prognostic unfavorable (5.76e-4)" "unprognostic (5.04e-2)" "unprognostic (3.63e-1)" "unprognostic (7.29e-3)" "unprognostic (5.14e-2)" "unprognostic (2.13e-2)" "unprognostic (3.33e-1)" "unprognostic (3.01e-2)" "unprognostic (1.72e-1)" "unprognostic (4.46e-2)" "unprognostic (6.52e-2)" "unprognostic (2.08e-2)" "unprognostic (5.80e-2)" "unprognostic (1.82e-3)" "unprognostic (7.33e-2)" "unprognostic (1.15e-2)" "unprognostic (5.73e-2)" "unprognostic (4.11e-1)" PGBD4 "FLJ32638, FLJ37497" ENSG00000182405 "PiggyBac transposable element derived 4" Q96DM1 15 34102083-34108686 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 4.9" "Cell type enhanced" "Detected in many" "Late spermatids: 14.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.8" "Lineage enriched" "Detected in single" 4 "granulocytes: 3.8" "Low cancer specificity" "Detected in many" "Spleen - B-cells (Spleen), Testis - Early spermatids" "HPA040896, HPA059823" Uncertain Approved Nucleoplasm,Centrosome NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 40: Non-specific - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" Nucleoplasm Centrosome "HPA040896: , HPA059823: " "unprognostic (9.78e-2)" "unprognostic (6.80e-2)" "unprognostic (7.84e-2)" "unprognostic (5.10e-2)" "unprognostic (5.29e-2)" "unprognostic (1.20e-1)" "potential prognostic favorable (5.44e-4)" "unprognostic (5.29e-2)" "unprognostic (1.03e-2)" "unprognostic (2.64e-1)" "unprognostic (1.83e-2)" "unprognostic (8.00e-2)" "unprognostic (4.21e-2)" "unprognostic (2.06e-1)" "unprognostic (1.35e-1)" "unprognostic (9.68e-3)" "unprognostic (2.26e-3)" "unprognostic (4.97e-3)" "unprognostic (3.33e-1)" "unprognostic (3.21e-1)" "unprognostic (7.87e-3)" "unprognostic (1.05e-2)" "unprognostic (3.66e-1)" "unprognostic (5.28e-2)" PGBD5 "DKFZp761A0620, FLJ11413" ENSG00000177614 "PiggyBac transposable element derived 5" Q8N414 1 230314490-230426332 "Disease related genes, Predicted intracellular proteins" Transposition "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.4;cervix: 17.0;pancreas: 19.1" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 172.2;Brain inhibitory neurons: 89.9;Cone photoreceptor cells: 70.4;Hofbauer cells: 65.8;Lactotrophs: 82.4;Oligodendrocytes: 77.2;Retinal amacrine cells: 85.9;Retinal bipolar cells: 85.3;Salivary acinar cells: 121.4;Thyrotrophs: 102.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Minor Salivary Gland - Minor salivary glandular cells, Skin - Outer root sheath cells, Spleen - Macrophages, Stomach - Gastric enteroendocrine cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065010 Supported Nucleoplasm NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 51: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 35: Neurons - Synaptic function & neurogenesis" 1 Nucleoplasm "HPA065010: " "unprognostic (1.63e-1)" "unprognostic (4.21e-2)" "unprognostic (3.22e-1)" "unprognostic (3.56e-1)" "unprognostic (1.76e-1)" "unprognostic (3.57e-3)" "potential prognostic unfavorable (4.86e-5)" "unprognostic (3.87e-3)" "unprognostic (1.46e-2)" "unprognostic (2.53e-1)" "potential prognostic favorable (3.00e-5)" "unprognostic (1.58e-3)" "unprognostic (2.44e-3)" "unprognostic (4.21e-3)" "unprognostic (3.75e-1)" "unprognostic (4.06e-2)" "unprognostic (1.96e-1)" "unprognostic (1.37e-1)" "unprognostic (6.94e-2)" "unprognostic (2.20e-1)" "unprognostic (6.30e-2)" "unprognostic (1.77e-2)" "unprognostic (4.34e-3)" "unprognostic (4.61e-1)" "unprognostic (3.82e-3)" "unprognostic (6.28e-2)" "unprognostic (2.09e-1)" "unprognostic (1.19e-1)" "unprognostic (8.63e-2)" "unprognostic (1.23e-2)" "unprognostic (3.93e-2)" PGC ENSG00000096088 Progastricsin P20142 6 41736711-41754109 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins, Transporters" Digestion "Aspartyl protease, Hydrolase, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 46 "stomach 1: 57583.8" "Cell type enriched" "Detected in some" 4 "Gastric chief cells: 125641.8" "Cell type enhanced" "Detected in single" "deep-layer near-projecting: 1.1" "Group enriched" "Detected in many" 5 "Lung Adenocarcinoma (TCGA): 1841.6;Stomach Adenocarcinoma (TCGA): 2215.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 13 "Gastric cancer: 347.9" "Stomach - Chief cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA031717, HPA031718" Enhanced Approved Nucleoplasm "Secreted to digestive system" Enzyme NA NA 500000 "Cluster 60: Stomach - Digestion" "Cluster 2: Neurons - Nucleosome" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 97: Non-specific - Cellular respiration" Nucleoplasm "HPA031717: , HPA031718: " "unprognostic (5.78e-2)" "unprognostic (2.95e-2)" "unprognostic (1.58e-1)" "unprognostic (1.48e-1)" "unprognostic (2.78e-1)" "unprognostic (9.58e-2)" "unprognostic (2.46e-2)" "unprognostic (1.95e-2)" "unprognostic (2.10e-3)" "unprognostic (9.97e-3)" "unprognostic (2.54e-2)" "unprognostic (2.50e-1)" "unprognostic (8.51e-2)" "unprognostic (6.70e-3)" "unprognostic (2.98e-1)" "unprognostic (5.44e-2)" "unprognostic (5.80e-2)" "unprognostic (2.90e-1)" PGD ENSG00000142657 "Phosphogluconate dehydrogenase" P52209 1 10398592-10420511 "Enzymes, Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Gluconate utilization, Pentose shunt" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 377.9;esophagus: 483.2" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1297.4;Esophageal basal cells: 519.1;Esophageal suprabasal cells: 1122.9;Neutrophil progenitors: 928.6;Neutrophils: 902.3;Suprabasal keratinocytes: 328.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 1064.8;classical monocyte: 321.6;eosinophil: 1077.6;neutrophil: 334.4" "Group enriched" "Detected in all" 5 "granulocytes: 1077.6;monocytes: 321.6" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Macrophages, Heart muscle - Macrophages, Skin - Sebaceous gland cells, Spleen - Neutrophils_2, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031314, HPA031315" Enhanced Supported Approved "Nucleoplasm,Plasma membrane,Mitochondria,Cytosol" NA No 36000000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 7 Cytosol "Nucleoplasm, Plasma membrane, Mitochondria" "HPA031314: , HPA031315: " "unprognostic (1.69e-1)" "unprognostic (2.59e-1)" "unprognostic (1.53e-1)" "unprognostic (2.79e-1)" "unprognostic (8.75e-3)" "unprognostic (3.00e-1)" "unprognostic (9.46e-2)" "unprognostic (1.74e-1)" "unprognostic (2.09e-1)" "unprognostic (1.53e-2)" "potential prognostic favorable (7.54e-4)" "unprognostic (9.94e-3)" "unprognostic (1.28e-1)" "validated prognostic unfavorable (7.01e-5)" "validated prognostic unfavorable (6.71e-5)" "unprognostic (2.88e-3)" "unprognostic (1.40e-1)" "unprognostic (9.53e-2)" "unprognostic (2.35e-2)" "unprognostic (2.41e-1)" "unprognostic (2.18e-1)" "unprognostic (2.05e-1)" "unprognostic (3.09e-1)" "unprognostic (1.11e-1)" "unprognostic (8.80e-2)" "unprognostic (1.74e-1)" "unprognostic (9.32e-2)" "unprognostic (6.39e-2)" "unprognostic (2.25e-1)" "unprognostic (8.43e-3)" "unprognostic (3.99e-2)" PGF "D12S1900, PGFL, PIGF, PLGF, PlGF-2, SHGC-10760" ENSG00000119630 "Placental growth factor" P49763 14 74941834-74955626 "Cancer-related genes, Candidate cardiovascular disease genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 66.8" "Group enriched" "Detected in many" 7 "Extravillous trophoblasts: 2360.8;Syncytiotrophoblasts: 2809.4" "Group enriched" "Detected in some" 5 "pericyte: 117.7;vascular associated smooth muscle cell: 79.9" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 138.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 41.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "spinal cord: 12.2" HPA041624 Approved Nucleoplasm,Mitochondria,Cytosol "Secreted to blood" "Growth factor" No No 20800 "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 44: Non-specific - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 2 Nucleoplasm "Mitochondria, Cytosol" "HPA041624: " "unprognostic (6.22e-2)" "unprognostic (2.41e-3)" "unprognostic (2.76e-1)" "unprognostic (1.11e-1)" "unprognostic (1.96e-2)" "unprognostic (9.92e-2)" "unprognostic (1.30e-2)" "unprognostic (1.70e-3)" "unprognostic (1.09e-1)" "unprognostic (3.70e-2)" "potential prognostic unfavorable (7.33e-4)" "unprognostic (2.33e-2)" "potential prognostic unfavorable (2.67e-5)" "potential prognostic unfavorable (3.18e-4)" "unprognostic (2.14e-1)" "unprognostic (5.53e-2)" "potential prognostic unfavorable (6.21e-5)" "unprognostic (6.96e-3)" "unprognostic (5.08e-2)" "unprognostic (1.17e-1)" "unprognostic (4.30e-3)" "unprognostic (6.48e-3)" "unprognostic (1.72e-2)" "unprognostic (5.25e-3)" "unprognostic (9.52e-3)" "unprognostic (8.82e-3)" "unprognostic (1.97e-1)" "unprognostic (3.42e-3)" "unprognostic (9.40e-2)" "unprognostic (2.93e-2)" "unprognostic (4.33e-2)" PGGHG "ATHL1, FLJ22635" ENSG00000142102 "Protein-glucosylgalactosylhydroxylysine glucosidase" Q32M88 11 289126-296107 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "pancreas: 622.9" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 46.7;Innate lymphoid cells: 61.5;Loop of henle epithelial cells: 53.4;Neutrophils: 105.4;Pancreatic acinar cells: 90.8;Papillary tip epithelial cells: 71.7;Proximal tubule cells: 46.5;Renal collecting duct principal cells: 122.4;Tuft cells: 46.1" "Cell type enhanced" "Detected in some" "leukocyte: 72.3" "Cancer enhanced" "Detected in all" "Kidney Renal Papillary Cell Carcinoma (TCGA): 119.3" "Region enriched" "Detected in all" 5 "cerebral cortex: 50.9" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - T-cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA039383, HPA058829" Uncertain Enhanced Cytosol NA Yes "Cluster 15: NK-cells - Unknown function" "Cluster 8: Pancreas - Proteolysis" "Cluster 12: Non-specific - Vasculature" "Cluster 59: Leukemia - T-cell receptor" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 1 Cytosol "HPA039383: , HPA058829: " "unprognostic (4.87e-2)" "unprognostic (1.68e-3)" "unprognostic (5.85e-2)" "unprognostic (1.61e-2)" "unprognostic (3.58e-1)" "potential prognostic unfavorable (9.35e-4)" "unprognostic (1.73e-3)" "unprognostic (2.67e-2)" "unprognostic (1.45e-2)" "potential prognostic unfavorable (9.84e-4)" "unprognostic (1.79e-1)" "potential prognostic favorable (3.22e-4)" "unprognostic (6.42e-2)" "unprognostic (6.52e-3)" "unprognostic (1.57e-1)" "unprognostic (2.78e-1)" "unprognostic (3.29e-1)" "unprognostic (2.18e-1)" "unprognostic (5.51e-2)" "unprognostic (1.58e-2)" "unprognostic (1.20e-2)" "unprognostic (1.10e-1)" "unprognostic (9.32e-2)" "unprognostic (3.47e-1)" "unprognostic (1.41e-2)" "potential prognostic favorable (5.56e-4)" "unprognostic (9.75e-2)" "unprognostic (2.22e-2)" "unprognostic (1.74e-1)" PGGT1B "BGGI, GGTI" ENSG00000164219 "Protein geranylgeranyltransferase type I subunit beta" P53609 5 115204012-115262877 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Prenyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030646 Uncertain Approved "Nucleoplasm,Endoplasmic reticulum,Cytosol" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 21: Non-specific - Metabolism" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 6 "Nucleoplasm, Endoplasmic reticulum" Cytosol "HPA030646: " "unprognostic (8.97e-2)" "unprognostic (2.57e-2)" "unprognostic (1.55e-2)" "unprognostic (3.95e-3)" "unprognostic (4.44e-3)" "unprognostic (1.35e-3)" "unprognostic (4.94e-2)" "unprognostic (7.27e-2)" "unprognostic (5.96e-2)" "unprognostic (1.59e-1)" "validated prognostic favorable (2.22e-7)" "validated prognostic favorable (2.47e-4)" "unprognostic (1.42e-1)" "unprognostic (1.38e-1)" "unprognostic (6.06e-2)" "unprognostic (4.59e-2)" "unprognostic (2.10e-2)" "unprognostic (2.24e-1)" "unprognostic (1.37e-1)" "unprognostic (1.70e-3)" "unprognostic (4.59e-2)" "potential prognostic unfavorable (4.05e-4)" "unprognostic (8.32e-2)" "unprognostic (1.50e-1)" "unprognostic (5.04e-3)" "unprognostic (1.17e-1)" "unprognostic (2.44e-1)" "unprognostic (3.60e-1)" "unprognostic (4.82e-1)" "potential prognostic unfavorable (6.28e-4)" "unprognostic (1.38e-1)" PGK1 ENSG00000102144 "Phosphoglycerate kinase 1" P00558 X 77910739-78129295 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis "Kinase, Transferase" "Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1662.0;Esophageal suprabasal cells: 673.6;Extravillous trophoblasts: 975.1;Neutrophils: 780.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010065, HPA045385, HPA073644, HPA073656" Approved Approved "Mid piece,Principal piece,End piece" NA NA 110000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 47 "Mid piece, Principal piece, End piece" "CAB010065: , HPA045385: , HPA073644: , HPA073656: " "unprognostic (3.68e-2)" "potential prognostic unfavorable (4.66e-7)" "unprognostic (2.77e-2)" "potential prognostic unfavorable (1.48e-4)" "unprognostic (4.24e-2)" "unprognostic (1.63e-1)" "unprognostic (2.45e-2)" "unprognostic (3.82e-2)" "potential prognostic unfavorable (8.69e-6)" "potential prognostic unfavorable (1.73e-4)" "potential prognostic favorable (3.20e-7)" "unprognostic (2.02e-1)" "unprognostic (1.32e-1)" "potential prognostic unfavorable (6.75e-4)" "unprognostic (2.50e-2)" "unprognostic (7.68e-3)" "potential prognostic unfavorable (1.17e-4)" "unprognostic (6.00e-2)" "unprognostic (1.44e-1)" "unprognostic (8.13e-2)" "unprognostic (8.80e-2)" "unprognostic (1.90e-3)" "unprognostic (5.25e-2)" "unprognostic (4.04e-2)" "unprognostic (1.99e-2)" "unprognostic (2.40e-1)" "unprognostic (2.60e-2)" "unprognostic (1.66e-2)" "unprognostic (2.32e-1)" "unprognostic (5.51e-3)" "unprognostic (3.28e-1)" PGK2 "PGK-2, PGKPS" ENSG00000170950 "Phosphoglycerate kinase 2" P07205 6 49785660-49787285 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 526 "testis: 186.8" "Cell type enriched" "Detected in some" 4 "Late spermatids: 4751.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045385, HPA073644, HPA073656" Supported Approved "Mid piece,Principal piece,End piece" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 13 "Mid piece, Principal piece, End piece" "HPA045385: , HPA073644: , HPA073656: " PGLS 6PGL ENSG00000130313 6-phosphogluconolactonase O95336 19 17511636-17521288 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 555.7;Esophageal suprabasal cells: 444.6;Hofbauer cells: 389.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040744, HPA042032" Approved Supported Nucleoplasm,Cytosol NA NA 3500000 "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 4 Nucleoplasm Cytosol "HPA040744: , HPA042032: " "unprognostic (2.58e-1)" "unprognostic (2.79e-2)" "unprognostic (2.42e-1)" "unprognostic (3.67e-2)" "unprognostic (5.40e-2)" "unprognostic (3.28e-1)" "unprognostic (1.90e-1)" "unprognostic (5.73e-2)" "unprognostic (1.40e-1)" "unprognostic (1.06e-1)" "potential prognostic unfavorable (1.97e-5)" "unprognostic (1.48e-3)" "unprognostic (1.73e-1)" "unprognostic (1.58e-3)" "potential prognostic unfavorable (2.88e-4)" "unprognostic (2.27e-2)" "unprognostic (6.78e-2)" "unprognostic (3.83e-1)" "unprognostic (1.17e-1)" "unprognostic (2.76e-2)" "unprognostic (1.90e-1)" "unprognostic (6.66e-2)" "unprognostic (2.84e-2)" "unprognostic (1.64e-1)" "unprognostic (3.02e-1)" "unprognostic (7.94e-2)" "unprognostic (7.02e-2)" "unprognostic (3.28e-1)" "unprognostic (1.98e-1)" "unprognostic (1.59e-1)" "unprognostic (3.32e-2)" PGLYRP1 "PGLYRP, PGRP, PGRP-S, PGRPS, TAG7, TNFSF3L" ENSG00000008438 "Peptidoglycan recognition protein 1" O75594 19 46019153-46023053 "Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "bone marrow: 594.9" "Group enriched" "Detected in some" 78 "Neutrophil progenitors: 1143.2;Neutrophils: 428.8" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 202 "eosinophil: 445.1;neutrophil: 497.3" "Lineage enriched" "Detected in many" 213 "granulocytes: 497.3" "Low cancer specificity" "Detected in some" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Lung - Neutrophils_1, Lung - Neutrophils_2, Thyroid gland - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045702, HPA070227" Enhanced Approved Nucleoplasm,Vesicles,Cytosol "Secreted to blood" Immunity NA NA 9100000 "Cluster 21: Neutrophils - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 15: Non-specific - Transcription" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 2 Vesicles "Nucleoplasm, Cytosol" "HPA045702: , HPA070227: " "unprognostic (1.56e-1)" "unprognostic (1.51e-1)" PGLYRP2 "PGLYRPL, PGRP-L, PGRPL, tagL, tagL-alpha, tagl-beta, TAGL-like" ENSG00000161031 "Peptidoglycan recognition protein 2" Q96PD5 19 15468645-15498956 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Immunity Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 36 "liver: 241.7" "Cell type enriched" "Detected in some" 10 "Hepatocytes: 199.1" "Cell type enhanced" "Detected in some" "leukocyte: 3.7" "Cancer enriched" "Detected in some" 10 "Liver Hepatocellular Carcinoma (TCGA): 92.8" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "granulocytes: 3.4;monocytes: 5.1;T-cells: 2.3" "Group enriched" "Detected in some" 4 "Bone cancer: 4.9;breast cancer: 5.8" "Liver - Hepatocytes, Minor Salivary Gland - Plasma cells, Testis - Sertoli cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB033468, HPA046311, HPA075237" Supported Approved "Cell Junctions" "Secreted to blood" Immunity NA NA 21000000000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 27: Breast cancer - Unknown function" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" "Cell Junctions" "CAB033468: , HPA046311: , HPA075237: " "unprognostic (9.41e-2)" "unprognostic (2.49e-2)" "unprognostic (9.82e-3)" "potential prognostic favorable (8.99e-4)" PGLYRP3 "PGLYRPIalpha, PGRP-Ialpha, PGRPIA" ENSG00000159527 "Peptidoglycan recognition protein 3" Q96LB9 1 153297116-153312952 "Metabolic proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "esophagus: 27.2;skin 1: 49.2" "Group enriched" "Detected in some" 7 "Esophageal apical cells: 227.2;Esophageal suprabasal cells: 73.4;Suprabasal keratinocytes: 60.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 12.5;Head and Neck Squamous Cell Carcinoma (TCGA): 23.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "basophil: 8.4;eosinophil: 3.7" "Lineage enriched" "Detected in single" 55 "granulocytes: 8.4" "Cancer enhanced" "Detected in some" "head and neck cancer: 4.9" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA030369 Uncertain "Secreted in other tissues" Immunity NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 58: Skin - Keratinization" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 15 "HPA030369: " "unprognostic (4.91e-3)" "unprognostic (3.57e-2)" "unprognostic (1.02e-1)" "unprognostic (4.45e-2)" "unprognostic (2.18e-1)" "unprognostic (1.89e-1)" "unprognostic (2.08e-1)" "unprognostic (2.19e-1)" PGLYRP4 "PGLYRPIbeta, PGRP-Ibeta, PGRPIB, SBBI67" ENSG00000163218 "Peptidoglycan recognition protein 4" Q96LB8 1 153330120-153348841 "Metabolic proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "cervix: 9.9;esophagus: 7.3;skin 1: 13.5;vagina: 9.0" "Cell type enhanced" "Detected in some" "Esophageal apical cells: 38.6;Esophageal basal cells: 5.8;Esophageal suprabasal cells: 20.2;Ocular epithelial cells: 8.6;Paneth cells: 3.9;Salivary duct cells: 4.6;Suprabasal keratinocytes: 18.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Head and Neck Squamous Cell Carcinoma (TCGA): 11.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "head and neck cancer: 7.3" "Lung - Respiratory ciliated cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB025879 Approved "Vesicles,Plasma membrane" "Secreted in other tissues" Immunity NA NA "Cluster 58: Skin - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" "Vesicles, Plasma membrane" "CAB025879: " "unprognostic (8.44e-2)" "unprognostic (1.24e-1)" "unprognostic (3.64e-3)" "unprognostic (4.05e-2)" "unprognostic (9.87e-2)" "unprognostic (2.92e-1)" "unprognostic (9.93e-2)" "unprognostic (1.49e-1)" PGM1 ENSG00000079739 "Phosphoglucomutase 1" P36871 1 63593411-63660245 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" Isomerase "Congenital disorder of glycosylation, Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "skeletal muscle: 1460.8;tongue: 735.9" "Cell type enhanced" "Detected in many" "Breast lactating cells: 250.0;Cardiomyocytes: 203.4;Extravillous trophoblasts: 300.5;Granulosa cells: 219.0;Hepatocytes: 305.8;Myonuclei: 368.0;Pancreatic acinar cells: 203.4;Thymic myoid cells: 225.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Liver - Hepatocytes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "CAB004666, HPA024190, HPA024637, HPA046329" Enhanced Supported Cytosol NA NA 20000000 "Cluster 35: Neutrophils - Protein binding" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 21: Non-specific - Metabolism" "Cluster 15: Kidney cancer - Membrane components" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 15 Cytosol "CAB004666: , HPA024190: , HPA024637: , HPA046329: " "unprognostic (1.11e-1)" "unprognostic (2.83e-1)" "unprognostic (1.21e-1)" "potential prognostic unfavorable (3.32e-4)" "unprognostic (5.74e-3)" "unprognostic (3.37e-2)" "unprognostic (2.17e-1)" "unprognostic (1.43e-2)" "unprognostic (6.07e-2)" "unprognostic (5.71e-2)" "potential prognostic favorable (7.55e-4)" "unprognostic (1.23e-2)" "unprognostic (7.35e-2)" "unprognostic (1.61e-2)" "unprognostic (1.52e-1)" "unprognostic (3.29e-3)" "unprognostic (6.60e-3)" "unprognostic (6.64e-3)" "unprognostic (9.37e-2)" "unprognostic (2.48e-1)" "unprognostic (1.21e-1)" "unprognostic (1.62e-3)" "unprognostic (6.14e-3)" "unprognostic (1.03e-1)" "unprognostic (1.06e-1)" "unprognostic (6.87e-2)" "unprognostic (2.60e-2)" "unprognostic (2.79e-2)" "unprognostic (1.81e-1)" "unprognostic (1.49e-1)" "unprognostic (1.02e-1)" PGM2 FLJ10983 ENSG00000169299 "Phosphoglucomutase 2" Q96G03 4 37826660-37862937 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 284.6;Esophageal suprabasal cells: 194.4;Megakaryocytes: 173.1;Müller glia: 438.9;Syncytiotrophoblasts: 121.4" "Cell type enhanced" "Detected in all" "vascular associated smooth muscle cell: 55.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040676 Uncertain Approved "Intermediate filaments,Cytosol" NA NA 2200000 "Cluster 29: Non-specific - Unknown function" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 35: Non-specific - DNA binding" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 11: Muller glia cells - Retinal homeostasis" 11 "Intermediate filaments" Cytosol "HPA040676: " "unprognostic (1.58e-1)" "unprognostic (4.13e-2)" "unprognostic (5.92e-3)" "unprognostic (8.05e-3)" "potential prognostic favorable (2.78e-5)" "unprognostic (2.23e-2)" "unprognostic (1.18e-1)" "unprognostic (1.54e-1)" "unprognostic (8.92e-2)" "potential prognostic unfavorable (6.53e-4)" "potential prognostic favorable (2.91e-7)" "unprognostic (6.63e-3)" "unprognostic (3.20e-2)" "unprognostic (3.87e-2)" "unprognostic (1.21e-1)" "potential prognostic unfavorable (1.09e-6)" "unprognostic (3.65e-2)" "unprognostic (2.37e-1)" "unprognostic (1.68e-1)" "potential prognostic unfavorable (5.65e-4)" "unprognostic (2.74e-1)" "unprognostic (1.21e-2)" "unprognostic (8.93e-2)" "unprognostic (7.39e-2)" "unprognostic (3.12e-2)" "unprognostic (4.35e-2)" "unprognostic (5.57e-2)" "unprognostic (1.90e-1)" "unprognostic (1.60e-1)" "unprognostic (1.04e-1)" "unprognostic (4.46e-1)" PGM2L1 "BM32A, FLJ32029" ENSG00000165434 "Phosphoglucomutase 2 like 1" Q6PCE3 11 74330316-74398433 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" "Isomerase, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 37.1" "Cell type enhanced" "Detected in many" "Gonadotrophs: 192.9;Pancreatic acinar cells: 232.9;Pituicytes/FSCs: 239.0;Respiratory ciliated cells: 157.2;Schwann cells: 236.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Liver - Vascular endothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Skin - Endothelial cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056995, HPA060948" Enhanced Approved Mitochondria No No 140000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 73: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 72: Neuronal - Signal transduction" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 1 Mitochondria "HPA056995: , HPA060948: " "unprognostic (3.72e-2)" "unprognostic (1.13e-2)" "unprognostic (6.96e-2)" "unprognostic (3.21e-1)" "unprognostic (3.54e-2)" "unprognostic (2.63e-2)" "unprognostic (1.40e-2)" "unprognostic (2.69e-2)" "unprognostic (3.04e-1)" "unprognostic (6.48e-3)" "unprognostic (2.30e-3)" "potential prognostic favorable (4.81e-4)" "unprognostic (1.15e-1)" "unprognostic (1.24e-2)" "unprognostic (1.78e-2)" "potential prognostic unfavorable (3.67e-4)" "unprognostic (8.30e-2)" "unprognostic (3.02e-1)" "unprognostic (2.38e-2)" "unprognostic (9.46e-2)" "unprognostic (9.22e-3)" "unprognostic (6.43e-2)" "unprognostic (2.78e-1)" "unprognostic (4.48e-2)" "unprognostic (1.01e-1)" "unprognostic (3.66e-1)" "unprognostic (1.87e-1)" "unprognostic (2.48e-1)" "unprognostic (3.29e-2)" "unprognostic (2.13e-1)" PGM3 "AGM1, DKFZP434B187, PAGM" ENSG00000013375 "Phosphoglucomutase 3" O95394 6 83147324-83193936 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism" Isomerase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pancreatic acinar cells: 162.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004998, HPA029759, HPA029760" Enhanced Approved Nucleoplasm,Cytosol NA NA 380000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 70: Non-specific - Protein processing" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 28: Non-specific - Nuclear processes" "Cluster 8: Non-specific - Secretory pathway" 14 "Nucleoplasm, Cytosol" "CAB004998: , HPA029759: , HPA029760: " "unprognostic (3.09e-1)" "unprognostic (1.23e-3)" "unprognostic (6.18e-2)" "potential prognostic unfavorable (6.76e-4)" "unprognostic (1.55e-2)" "unprognostic (1.72e-1)" "unprognostic (6.02e-2)" "unprognostic (1.91e-2)" "unprognostic (1.58e-2)" "unprognostic (2.35e-2)" "unprognostic (8.47e-3)" "unprognostic (3.12e-1)" "unprognostic (9.85e-3)" "unprognostic (2.40e-2)" "unprognostic (1.81e-2)" "unprognostic (4.40e-2)" "unprognostic (6.81e-3)" "unprognostic (2.06e-2)" "unprognostic (3.65e-2)" "unprognostic (1.57e-1)" "unprognostic (1.00e-1)" "unprognostic (3.57e-1)" "unprognostic (1.64e-2)" "unprognostic (1.49e-1)" "unprognostic (2.32e-3)" "unprognostic (1.86e-2)" "unprognostic (2.35e-1)" "unprognostic (1.40e-1)" "unprognostic (2.72e-1)" "unprognostic (1.85e-2)" "unprognostic (3.45e-1)" PGM5 PGMRP ENSG00000154330 "Phosphoglucomutase 5" Q15124 9 68328308-68531061 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 231.1;urinary bladder: 218.9" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 339.9;Cardiomyocytes: 193.8;Lymphatic endothelial cells: 532.9;Microglia: 246.9;Myonuclei: 219.2;Pituitary stem cells: 145.3;Retinal bipolar cells: 243.8;Retinal pigment epithelial cells: 200.4;Smooth muscle cells: 501.8;Vascular endothelial cells: 162.0;Vascular smooth muscle cells: 140.0" "Group enriched" "Detected in many" 6 "central nervous system macrophage: 314.7;endothelial cell: 453.4" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 47.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 48 "neutrophil: 4.8" "Lineage enriched" "Detected in single" 48 "granulocytes: 4.8" "Cancer enhanced" "Detected in many" "Sarcoma: 8.1" "Adipose subcutaneous - Smooth muscle cells, Kidney - Fibroblasts, Prostate - Smooth muscle cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034397, HPA046329, HPA067102" Enhanced Uncertain Cytosol NA NA 250000 "Cluster 35: Neutrophils - Protein binding" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 25: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" Cytosol "CAB034397: , HPA046329: , HPA067102: " "unprognostic (1.10e-2)" "unprognostic (3.46e-1)" "unprognostic (6.02e-3)" "unprognostic (1.38e-2)" "unprognostic (2.47e-2)" "unprognostic (3.02e-1)" "unprognostic (2.51e-1)" "unprognostic (1.34e-1)" "unprognostic (1.15e-1)" "unprognostic (2.88e-2)" "validated prognostic favorable (8.13e-8)" "validated prognostic favorable (1.61e-6)" "unprognostic (1.30e-1)" "validated prognostic favorable (1.57e-4)" "validated prognostic favorable (8.36e-4)" "potential prognostic favorable (7.63e-4)" "unprognostic (9.17e-3)" "unprognostic (5.52e-2)" "unprognostic (5.01e-2)" "unprognostic (7.87e-3)" "unprognostic (9.00e-2)" "unprognostic (4.76e-2)" "unprognostic (2.19e-1)" "unprognostic (2.60e-2)" "unprognostic (1.30e-2)" "unprognostic (1.05e-2)" "unprognostic (1.39e-1)" "unprognostic (5.46e-3)" "unprognostic (1.81e-1)" "unprognostic (1.93e-1)" "unprognostic (1.48e-1)" PGP ENSG00000184207 "Phosphoglycolate phosphatase" A6NDG6 16 2211593-2214840 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 59.6" "Cell type enriched" "Detected in many" 5 "Late spermatids: 2429.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043096, HPA046739" Approved Approved "Nuclear bodies" NA NA 260000 "Cluster 22: Eosinophils - Transcription" "Cluster 67: Testis - Mixed function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 54: Non-specific - Transcription" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 3 "Nuclear bodies" "HPA043096: , HPA046739: " "unprognostic (1.17e-1)" "unprognostic (9.04e-2)" "unprognostic (2.27e-1)" "unprognostic (2.29e-1)" "unprognostic (7.20e-2)" "unprognostic (4.11e-2)" "potential prognostic unfavorable (4.88e-4)" "unprognostic (1.27e-3)" "unprognostic (7.24e-2)" "unprognostic (3.71e-2)" "unprognostic (2.13e-3)" "potential prognostic unfavorable (6.23e-4)" "unprognostic (1.19e-1)" "unprognostic (9.57e-3)" "potential prognostic unfavorable (5.54e-5)" "unprognostic (9.75e-3)" "unprognostic (3.52e-1)" "unprognostic (1.25e-1)" "potential prognostic favorable (3.19e-5)" "potential prognostic favorable (9.99e-4)" "unprognostic (2.06e-1)" "unprognostic (1.53e-1)" "unprognostic (1.05e-2)" "unprognostic (8.20e-2)" "unprognostic (1.28e-1)" "unprognostic (7.05e-2)" "unprognostic (1.14e-1)" "unprognostic (2.78e-1)" "unprognostic (1.89e-1)" "unprognostic (6.87e-2)" "unprognostic (2.14e-1)" PGPEP1 "Pcp, PGP, PGP-I, PGPI" ENSG00000130517 "Pyroglutamyl-peptidase I" Q9NXJ5 19 18340598-18369950 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 93.8;Hepatocytes: 90.9;Proximal tubule cells: 105.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 28.2" "Lineage enriched" "Detected in all" 4 "granulocytes: 28.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035368, HPA055277" Approved Approved "Golgi apparatus" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 70: Non-specific - Protein processing" "Cluster 44: Non-specific - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" "Golgi apparatus" "HPA035368: , HPA055277: " "unprognostic (6.21e-3)" "unprognostic (4.82e-2)" "unprognostic (3.44e-1)" "unprognostic (1.42e-1)" "unprognostic (1.03e-1)" "unprognostic (3.64e-1)" "unprognostic (5.59e-2)" "potential prognostic unfavorable (3.64e-5)" "unprognostic (2.08e-2)" "unprognostic (4.22e-3)" "validated prognostic favorable (9.10e-9)" "validated prognostic favorable (2.13e-4)" "potential prognostic favorable (7.97e-5)" "unprognostic (5.75e-2)" "unprognostic (1.28e-1)" "potential prognostic favorable (3.15e-4)" "unprognostic (4.91e-2)" "unprognostic (2.06e-1)" "unprognostic (4.00e-2)" "unprognostic (3.75e-2)" "unprognostic (1.05e-1)" "unprognostic (3.97e-3)" "unprognostic (1.80e-1)" "unprognostic (1.97e-2)" "unprognostic (5.97e-3)" "unprognostic (1.52e-1)" "unprognostic (1.31e-2)" "unprognostic (8.93e-3)" "unprognostic (2.56e-1)" "unprognostic (5.73e-3)" "unprognostic (3.29e-2)" PGPEP1L ENSG00000183571 "Pyroglutamyl-peptidase I like" A6NFU8 15 98968229-99007792 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 4 "skeletal muscle: 28.6" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Kidney Chromophobe (TCGA): 1.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Myeloma: 1.1" "Adipose subcutaneous - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA041781 Uncertain Approved "Plasma membrane,Cytosol,Equatorial segment" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 33: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 46: Skeletal myocytes - Muscle structure & formation" "Equatorial segment" "Plasma membrane, Cytosol" "HPA041781: " "unprognostic (9.18e-2)" PGR "NR3C3, PR" ENSG00000082175 "Progesterone receptor" P06401 11 101029624-101129813 "Cancer-related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors, Transporters" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "cervix: 59.9;endometrium 1: 96.6;fallopian tube: 32.3;smooth muscle: 73.3" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 131.5;Cardiomyocytes: 348.9;Decidual stromal cells: 136.5;Endometrial ciliated cells: 148.4;Endometrial stromal cells: 318.7;Epididymal efferent duct absorptive cells: 184.4;Fallopian secretory cells: 219.6;Fallopian tube ciliated cells: 335.0;Gonadotrophs: 349.7;Smooth muscle cells: 106.1" "Group enriched" "Detected in many" 6 "endothelial cell: 121.0;ependymal cell: 32.7;fibroblast: 83.6;pericyte: 55.4;vascular associated smooth muscle cell: 37.6" "Group enriched" "Detected in some" 7 "Breast Invasive Carcinoma (TCGA): 20.6;Uterine Corpus Endometrial Carcinoma (TCGA): 15.7" "Region enriched" "Detected in all" 5 "hypothalamus: 19.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 27 "breast cancer: 7.2" "Breast - Breast glandular cells, Liver - Hepatic stellate cells, Lung - Fibroblasts_1, Pituitary gland - Gonadotropes, Prostate - Fibroblasts, Spleen - Endothelial cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB000068, HPA004751, HPA008428, HPA017176, CAB055100" Enhanced NA NA "Cluster 75: Ovary - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 27: Breast cancer - Unknown function" "Cluster 108: Fibroblasts - ECM organization" 30 "CAB000068: , CAB055100: , HPA004751: , HPA008428: , HPA017176: " "unprognostic (8.34e-2)" "unprognostic (2.63e-1)" "unprognostic (6.88e-2)" "unprognostic (2.46e-1)" "unprognostic (1.03e-1)" "unprognostic (2.26e-1)" "unprognostic (3.72e-2)" "unprognostic (9.08e-2)" "unprognostic (3.23e-1)" "unprognostic (7.95e-3)" "unprognostic (5.12e-3)" PGRMC1 HPR6.6 ENSG00000101856 "Progesterone receptor membrane component 1" O00264 X 119236245-119244466 "Predicted membrane proteins, Predicted secreted proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 633.3" "Cell type enhanced" "Detected in many" "Hepatocytes: 523.0;Platelets: 1900.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Colon - Colon enteroendocrine cells, Liver - Hepatocytes, Liver - Hepatocytes, Skeletal muscle - Endothelial cells, Testis - Leydig cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002877, HPA064724" Enhanced Approved "Nucleoli,Endoplasmic reticulum,Mid piece,Principal piece" "Secreted - unknown location" Receptor NA NA 530000 "Cluster 29: Non-specific - Unknown function" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 27: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 47: Platelets - Hemostasis" 178 "Endoplasmic reticulum" "Nucleoli, Mid piece, Principal piece" "HPA002877: , HPA064724: " "unprognostic (2.68e-2)" "unprognostic (1.71e-2)" "unprognostic (1.04e-1)" "unprognostic (2.11e-2)" "unprognostic (3.25e-1)" "unprognostic (3.14e-2)" "unprognostic (1.25e-2)" "unprognostic (2.27e-1)" "unprognostic (1.15e-3)" "unprognostic (4.75e-2)" "potential prognostic favorable (8.25e-6)" "unprognostic (1.77e-1)" "unprognostic (4.75e-3)" "unprognostic (6.99e-3)" "unprognostic (2.63e-3)" "unprognostic (9.35e-2)" "unprognostic (5.21e-2)" "unprognostic (1.74e-2)" "unprognostic (3.95e-2)" "unprognostic (6.71e-2)" "unprognostic (1.49e-1)" "unprognostic (7.78e-2)" "unprognostic (3.68e-1)" "unprognostic (1.88e-1)" "unprognostic (6.58e-2)" "unprognostic (3.63e-1)" "unprognostic (3.54e-2)" "unprognostic (1.25e-1)" "unprognostic (1.73e-1)" "unprognostic (1.43e-1)" "unprognostic (1.19e-1)" PGRMC2 "DG6, PMBP" ENSG00000164040 "Progesterone receptor membrane component 2" O15173 4 128269237-128288829 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 371.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041172, HPA058652" Approved Approved "Nuclear bodies,Plasma membrane,Cytosol" "Secreted - unknown location" Receptor NA NA 87000 "Cluster 41: Basophils - Unknown function" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 15: Kidney cancer - Membrane components" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." 124 "Nuclear bodies, Plasma membrane, Cytosol" "HPA041172: , HPA058652: " "unprognostic (6.95e-2)" "unprognostic (5.92e-3)" "unprognostic (2.32e-1)" "unprognostic (4.74e-2)" "unprognostic (1.97e-2)" "unprognostic (2.52e-1)" "unprognostic (3.02e-1)" "unprognostic (6.04e-2)" "unprognostic (5.46e-3)" "unprognostic (2.20e-3)" "validated prognostic favorable (1.05e-6)" "validated prognostic favorable (6.67e-4)" "unprognostic (5.01e-2)" "unprognostic (1.70e-2)" "unprognostic (1.75e-1)" "unprognostic (1.74e-2)" "unprognostic (3.61e-2)" "unprognostic (9.60e-2)" "unprognostic (2.23e-2)" "unprognostic (2.71e-1)" "unprognostic (1.70e-2)" "unprognostic (9.13e-2)" "unprognostic (1.76e-1)" "unprognostic (3.74e-2)" "unprognostic (6.10e-2)" "unprognostic (7.57e-2)" "unprognostic (2.12e-1)" "unprognostic (4.93e-2)" "unprognostic (6.67e-2)" "unprognostic (1.02e-1)" "unprognostic (2.45e-2)" PGS1 DKFZP762M186 ENSG00000087157 "Phosphatidylglycerophosphate synthase 1" Q32NB8 17 78378649-78425114 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Neutrophils: 869.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells, Kidney - Endothelial cells, Pancreas - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022526 Approved Approved "Vesicles,Plasma membrane,Cell Junctions,Mid piece" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 11: White matter - Signal transduction" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 24: Neutrophils - Innate immunity signal integration" 1 Vesicles "Plasma membrane, Cell Junctions, Mid piece" "HPA022526: " "unprognostic (2.98e-1)" "unprognostic (1.90e-1)" "unprognostic (1.30e-1)" "unprognostic (1.39e-1)" "unprognostic (4.18e-1)" "unprognostic (2.12e-1)" "unprognostic (8.00e-2)" "potential prognostic favorable (4.34e-4)" "unprognostic (1.40e-2)" "potential prognostic unfavorable (9.99e-5)" "unprognostic (9.85e-2)" "unprognostic (3.13e-1)" "unprognostic (1.79e-1)" "unprognostic (2.49e-3)" "potential prognostic unfavorable (7.63e-4)" "unprognostic (5.89e-2)" "unprognostic (9.23e-2)" "unprognostic (1.93e-1)" "unprognostic (1.19e-3)" "unprognostic (4.04e-2)" "unprognostic (5.81e-2)" "unprognostic (2.26e-3)" "unprognostic (2.53e-2)" "unprognostic (7.14e-2)" "unprognostic (1.09e-2)" "potential prognostic favorable (5.46e-5)" "unprognostic (1.83e-1)" "unprognostic (2.28e-1)" "unprognostic (2.25e-1)" "unprognostic (8.54e-3)" "unprognostic (4.28e-2)" PHACTR1 "dJ257A7.2, KIAA1733, RPEL1" ENSG00000112137 "Phosphatase and actin regulator 1" Q9C0D0 6 12716312-13290446 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Actin-binding, Protein phosphatase inhibitor" Epilepsy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 21.5;brain: 25.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 736.6;Brain excitatory neurons: 1327.4;Brain inhibitory neurons: 3935.6;Cardiomyocytes: 1321.1;Ependymal cells: 808.0;Neutrophils: 1133.6;Retinal amacrine cells: 884.7;Retinal horizontal cells: 769.3;Somatotrophs: 1069.8;Thyrotrophs: 1800.0" "Cell type enhanced" "Detected in all" "eccentric medium spiny neuron: 7764.7;medium spiny neuron: 9113.3" "Cancer enriched" "Detected in many" 8 "Skin Cutaneous Melanoma (TCGA): 70.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 16.1;plasmacytoid DC: 18.7" "Group enriched" "Detected in many" 13 "B-cells: 6.9;dendritic cells: 18.7;granulocytes: 16.1" "Cancer enhanced" "Detected in many" "lymphoma: 34.9;Myeloma: 29.5;skin cancer: 74.1" "Colon - Endothelial cells, Heart muscle - Cardiomyocytes, Liver - Vascular endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029755, HPA029756, HPA029757" Enhanced Uncertain "Plasma membrane" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 53: Neurons - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 35: Neurons - Synaptic function & neurogenesis" 3 "Plasma membrane" "HPA029755: , HPA029756: , HPA029757: " "unprognostic (3.69e-1)" "unprognostic (8.43e-2)" "unprognostic (7.69e-2)" "unprognostic (1.06e-1)" "unprognostic (3.13e-1)" "unprognostic (5.28e-2)" "unprognostic (2.25e-1)" "unprognostic (1.13e-3)" "unprognostic (1.80e-1)" "unprognostic (3.76e-1)" "unprognostic (8.92e-2)" "unprognostic (3.87e-1)" "unprognostic (2.33e-2)" "unprognostic (1.98e-2)" "unprognostic (2.23e-3)" "unprognostic (1.03e-1)" "unprognostic (7.57e-3)" "unprognostic (2.91e-1)" "unprognostic (3.84e-1)" "unprognostic (1.80e-2)" "unprognostic (1.06e-3)" "unprognostic (4.33e-2)" "unprognostic (2.48e-1)" "unprognostic (1.37e-1)" "unprognostic (1.33e-1)" "unprognostic (7.46e-2)" "unprognostic (8.41e-2)" "unprognostic (9.60e-2)" "unprognostic (6.16e-3)" "unprognostic (1.65e-2)" PHACTR2 "C6orf56, KIAA0680" ENSG00000112419 "Phosphatase and actin regulator 2" O75167 6 143536845-143831185 "Predicted intracellular proteins" "Actin-binding, Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 79.4" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 691.3;Choroid plexus epithelial cells: 2026.0;Foveolar cells: 532.1;Retinal pigment epithelial cells: 878.2" "Cell type enhanced" "Detected in all" "cerebellar inhibitory: 1025.8;choroid plexus epithelial cell: 1711.2" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 7 "choroid plexus: 354.2" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031719, HPA031720, HPA031725" Approved Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 7 "Golgi apparatus" "Plasma membrane" "HPA031719: , HPA031720: , HPA031725: " "unprognostic (1.04e-2)" "unprognostic (5.23e-2)" "unprognostic (1.61e-2)" "unprognostic (3.21e-3)" "unprognostic (2.11e-1)" "unprognostic (4.65e-2)" "unprognostic (4.42e-1)" "unprognostic (3.76e-2)" "unprognostic (1.20e-1)" "unprognostic (7.84e-3)" "validated prognostic favorable (9.94e-7)" "validated prognostic favorable (1.29e-4)" "unprognostic (1.06e-1)" "unprognostic (4.10e-2)" "unprognostic (1.95e-1)" "unprognostic (2.88e-2)" "unprognostic (1.18e-1)" "unprognostic (6.58e-2)" "unprognostic (1.32e-1)" "unprognostic (3.69e-2)" "unprognostic (3.20e-2)" "unprognostic (5.41e-2)" "unprognostic (4.19e-2)" "unprognostic (3.56e-1)" "unprognostic (8.34e-2)" "unprognostic (1.04e-2)" "unprognostic (2.07e-2)" "unprognostic (1.86e-1)" "unprognostic (1.98e-1)" "unprognostic (1.23e-1)" "potential prognostic unfavorable (1.94e-4)" PHACTR3 "C20orf101, PPP1R123" ENSG00000087495 "Phosphatase and actin regulator 3" Q96KR7 20 59577509-59847711 "Predicted intracellular proteins" "Actin-binding, Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 94.1;pituitary gland: 26.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 108.1;Astrocytes: 336.3;Brain excitatory neurons: 215.0;Brain inhibitory neurons: 131.1;Corticotrophs: 116.3;Oligodendrocyte progenitor cells: 502.1;Oligodendrocytes: 473.7;Oocytes: 152.0;Retinal amacrine cells: 238.8;Retinal ganglion cells: 285.8" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Glioblastoma Multiforme (TCGA): 17.4;Lung Adenocarcinoma (TCGA): 12.7;Pancreatic Adenocarcinoma (TCGA): 14.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Leukemia: 23.4;pancreatic cancer: 27.7" "Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Liver - Hepatic stellate cells, Pituitary gland - Corticotropes, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051834, HPA054847" Enhanced Nucleoplasm NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 34: Non-specific - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 9 Nucleoplasm "HPA051834: , HPA054847: " "unprognostic (5.10e-2)" "unprognostic (1.07e-1)" "unprognostic (1.24e-2)" "unprognostic (2.58e-1)" "unprognostic (2.34e-1)" "potential prognostic favorable (6.27e-4)" "unprognostic (1.79e-1)" "unprognostic (1.31e-2)" "unprognostic (3.73e-2)" "unprognostic (1.75e-1)" "unprognostic (1.78e-2)" "unprognostic (1.49e-1)" "unprognostic (4.55e-2)" "unprognostic (1.53e-1)" "unprognostic (7.39e-2)" "unprognostic (4.97e-3)" "unprognostic (1.33e-2)" "potential prognostic favorable (6.96e-4)" "unprognostic (3.46e-1)" "unprognostic (2.98e-1)" "unprognostic (1.61e-1)" "unprognostic (1.15e-3)" PHACTR4 "FLJ13171, PPP1R124" ENSG00000204138 "Phosphatase and actin regulator 4" Q8IZ21 1 28369582-28500364 "Predicted intracellular proteins" Neurogenesis "Actin-binding, Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial glandular cells: 733.8;Esophageal apical cells: 986.7;Podocytes: 753.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028985 Approved Approved "Plasma membrane,Intermediate filaments,Cytosol" NA Yes "Cluster 14: Non-specific - Unknown function" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 6: Non-specific - Immune response" "Cluster 37: Non-specific - mRNA processing" "Cluster 51: Secretory epithelial cells - Mixed function" 19 "Plasma membrane, Cytosol" "Intermediate filaments" "HPA028985: " "unprognostic (3.63e-3)" "unprognostic (4.24e-2)" "unprognostic (4.55e-2)" "unprognostic (3.76e-2)" "unprognostic (4.52e-2)" "unprognostic (1.02e-1)" "unprognostic (2.86e-1)" "unprognostic (4.12e-2)" "unprognostic (1.36e-2)" "unprognostic (9.98e-3)" "potential prognostic favorable (5.85e-4)" "unprognostic (1.63e-3)" "unprognostic (2.73e-1)" "unprognostic (8.59e-3)" "unprognostic (2.03e-2)" "unprognostic (1.01e-1)" "unprognostic (8.09e-2)" "unprognostic (1.70e-1)" "unprognostic (2.49e-1)" "unprognostic (1.12e-1)" "unprognostic (3.73e-1)" "unprognostic (3.59e-2)" "unprognostic (1.13e-1)" "unprognostic (1.45e-1)" "unprognostic (6.21e-2)" "unprognostic (1.86e-1)" "unprognostic (1.45e-1)" "unprognostic (1.40e-1)" "unprognostic (1.56e-1)" "unprognostic (6.01e-2)" "unprognostic (1.64e-1)" PHAF1 "C16orf6, C16orf70, FLJ12076, lin-10, LIN10" ENSG00000125149 "Phagosome assembly factor 1" Q9BSU1 16 67109941-67148544 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 54.0" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 111.8;Hepatocytes: 99.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041131, HPA041214" Approved Approved "Nucleoli fibrillar center,Nuclear speckles,Cytosol" No No "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 30: White matter - Myelination" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 51: Secretory epithelial cells - Mixed function" 13 "Nuclear speckles" "Nucleoli fibrillar center, Cytosol" "HPA041131: , HPA041214: " "unprognostic (9.55e-2)" "unprognostic (3.79e-2)" "unprognostic (2.82e-2)" "unprognostic (9.70e-2)" "unprognostic (2.85e-1)" "unprognostic (8.30e-2)" "unprognostic (1.60e-1)" "unprognostic (3.23e-3)" "unprognostic (1.22e-1)" "unprognostic (9.53e-2)" "unprognostic (2.66e-3)" "unprognostic (1.33e-1)" "unprognostic (2.77e-2)" "unprognostic (2.61e-1)" "unprognostic (5.91e-2)" "unprognostic (1.67e-1)" "unprognostic (7.20e-3)" "unprognostic (5.33e-2)" "unprognostic (6.94e-2)" "unprognostic (4.60e-2)" "unprognostic (3.54e-2)" "unprognostic (2.91e-3)" "unprognostic (4.75e-3)" "unprognostic (9.29e-2)" "unprognostic (4.14e-1)" "unprognostic (1.37e-1)" "unprognostic (1.34e-1)" "unprognostic (1.16e-1)" "unprognostic (2.16e-1)" "unprognostic (1.04e-1)" "unprognostic (7.34e-2)" PHAX "FLJ13193, RNUXA" ENSG00000164902 "Phosphorylated adaptor for RNA export" Q9H814 5 126600925-126627252 "Essential proteins, Predicted intracellular proteins, Transporters" "Protein transport, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059630, HPA070326" Supported Enhanced Nucleoplasm NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 31: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 17: Non-specific - RNA processing" 65 Nucleoplasm "HPA059630: , HPA070326: " "unprognostic (2.14e-2)" "potential prognostic unfavorable (3.86e-4)" "unprognostic (8.04e-3)" "unprognostic (3.45e-2)" "unprognostic (1.53e-1)" "unprognostic (4.26e-3)" "unprognostic (9.14e-2)" "unprognostic (1.70e-3)" "unprognostic (8.81e-2)" "unprognostic (1.25e-2)" "potential prognostic favorable (1.96e-7)" "unprognostic (2.05e-3)" "unprognostic (1.40e-1)" "unprognostic (3.65e-3)" "unprognostic (6.09e-2)" "unprognostic (3.70e-3)" "unprognostic (3.68e-2)" "unprognostic (6.78e-2)" "unprognostic (1.58e-1)" "unprognostic (6.26e-3)" "unprognostic (1.05e-2)" "unprognostic (4.25e-2)" "unprognostic (7.23e-3)" "unprognostic (1.50e-2)" "unprognostic (5.24e-3)" "unprognostic (1.22e-1)" "unprognostic (1.95e-2)" "unprognostic (1.93e-1)" "unprognostic (1.83e-1)" "unprognostic (7.95e-2)" "unprognostic (9.05e-2)" PHB1 PHB ENSG00000167085 "Prohibitin 1" P35232 17 49404049-49414905 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "DNA synthesis, Host-virus interaction" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 372.7;Salivary acinar cells: 356.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Stomach - Mitotic cells (Stomach), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" HPA003280 Supported Supported Mitochondria "Intracellular and membrane" Other NA NA 910000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 27: Breast cancer - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 140 Mitochondria "HPA003280: " "unprognostic (8.65e-3)" "unprognostic (5.51e-2)" "unprognostic (3.80e-1)" "unprognostic (1.46e-2)" "unprognostic (1.50e-2)" "unprognostic (1.77e-2)" "unprognostic (1.25e-1)" "unprognostic (5.21e-1)" "unprognostic (8.77e-3)" "unprognostic (1.63e-2)" "potential prognostic favorable (1.77e-6)" "unprognostic (1.13e-2)" "unprognostic (2.03e-3)" "unprognostic (2.02e-2)" "potential prognostic unfavorable (1.18e-8)" "unprognostic (1.16e-3)" "unprognostic (1.90e-1)" "unprognostic (2.05e-2)" "unprognostic (3.41e-2)" "unprognostic (8.73e-2)" "unprognostic (9.99e-2)" "unprognostic (2.62e-2)" "unprognostic (3.49e-1)" "unprognostic (1.07e-1)" "unprognostic (4.13e-3)" "unprognostic (1.39e-2)" "unprognostic (5.97e-2)" "unprognostic (3.84e-2)" "unprognostic (3.27e-1)" "unprognostic (3.03e-2)" "unprognostic (1.62e-1)" PHB2 "Bap37, BCAP37, p22, REA" ENSG00000215021 "Prohibitin 2" Q99623 12 6965327-6970780 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Receptor, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal basal cells: 396.2;Migrating cytotrophoblasts: 337.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB014889, CAB026335, HPA039874" Supported Enhanced Mitochondria NA NA 200000 "Cluster 13: Non-specific - Mitochondria" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 38: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 90 Mitochondria "CAB014889: , CAB026335: , HPA039874: " "unprognostic (1.36e-1)" "unprognostic (1.59e-2)" "unprognostic (1.05e-1)" "unprognostic (2.47e-1)" "unprognostic (1.86e-1)" "unprognostic (2.04e-1)" "unprognostic (1.90e-2)" "unprognostic (6.06e-2)" "unprognostic (9.55e-3)" "unprognostic (4.86e-2)" "potential prognostic favorable (1.56e-4)" "unprognostic (4.67e-3)" "unprognostic (1.10e-1)" "unprognostic (1.88e-2)" "potential prognostic unfavorable (2.25e-8)" "unprognostic (1.62e-3)" "unprognostic (1.04e-2)" "potential prognostic favorable (4.55e-4)" "unprognostic (3.05e-1)" "unprognostic (7.02e-3)" "unprognostic (1.06e-1)" "unprognostic (7.69e-2)" "unprognostic (6.72e-2)" "unprognostic (3.11e-1)" "unprognostic (8.92e-3)" "unprognostic (1.08e-1)" "unprognostic (1.31e-1)" "unprognostic (9.19e-2)" "unprognostic (1.28e-1)" "unprognostic (3.40e-3)" "unprognostic (3.49e-1)" PHC1 "EDR1, HPH1, RAE28" ENSG00000111752 "Polyhomeotic homolog 1" P78364 12 8913896-8941467 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein, DNA-binding" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 6 "Testicular Germ Cell Tumor (TCGA): 171.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in all" 5 "testis cancer: 164.2" "Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006973 Approved Supported "Nucleoplasm,Mid piece" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 34: Testis cancer - Unknown function" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 48 Nucleoplasm "Mid piece" "HPA006973: " "unprognostic (5.47e-2)" "unprognostic (2.13e-1)" "unprognostic (1.54e-1)" "unprognostic (8.44e-2)" "unprognostic (6.62e-2)" "unprognostic (3.48e-1)" "unprognostic (1.86e-1)" "unprognostic (3.26e-3)" "unprognostic (1.50e-1)" "unprognostic (1.63e-1)" "unprognostic (4.70e-2)" "unprognostic (3.42e-3)" "unprognostic (2.25e-1)" "unprognostic (9.24e-2)" "potential prognostic unfavorable (2.33e-4)" "unprognostic (5.75e-2)" "unprognostic (1.38e-1)" "unprognostic (1.16e-2)" "unprognostic (4.23e-2)" "unprognostic (1.48e-1)" "unprognostic (4.58e-2)" "unprognostic (3.90e-3)" "unprognostic (7.33e-3)" "unprognostic (7.89e-2)" "unprognostic (1.72e-2)" "potential prognostic favorable (1.73e-5)" "unprognostic (2.02e-1)" "unprognostic (3.26e-2)" "unprognostic (3.43e-1)" "unprognostic (2.01e-1)" "unprognostic (3.29e-1)" PHC2 "EDR2, HPH2" ENSG00000134686 "Polyhomeotic homolog 2" Q8IXK0 1 33323623-33431095 "Predicted intracellular proteins" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 314.5;Neutrophils: 897.2;Retinal horizontal cells: 300.5;Rod photoreceptor cells: 299.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 9 "neutrophil: 93.7" "Lineage enriched" "Detected in all" 11 "granulocytes: 93.7" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Skin - Macrophages, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047403 Supported Supported Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 72: Neuronal - Signal transduction" "Cluster 24: Neutrophils - Innate immunity signal integration" 89 Nucleoplasm "HPA047403: " "unprognostic (2.22e-2)" "unprognostic (3.61e-2)" "unprognostic (2.54e-1)" "unprognostic (1.21e-3)" "unprognostic (7.10e-2)" "unprognostic (9.62e-3)" "unprognostic (2.01e-1)" "unprognostic (6.70e-2)" "unprognostic (3.45e-2)" "unprognostic (1.91e-1)" "unprognostic (1.48e-2)" "unprognostic (1.04e-2)" "unprognostic (1.58e-1)" "validated prognostic unfavorable (2.57e-8)" "validated prognostic unfavorable (6.78e-4)" "validated prognostic unfavorable (7.85e-4)" "validated prognostic unfavorable (7.57e-7)" "unprognostic (4.31e-3)" "unprognostic (3.12e-3)" "unprognostic (2.93e-2)" "unprognostic (5.70e-2)" "unprognostic (4.77e-2)" "unprognostic (2.15e-1)" "unprognostic (5.71e-2)" "unprognostic (1.94e-1)" "unprognostic (6.46e-3)" "unprognostic (1.27e-1)" "unprognostic (3.43e-1)" "unprognostic (2.91e-2)" "unprognostic (7.20e-2)" "unprognostic (2.71e-3)" PHC3 "EDR3, FLJ12729, FLJ12967, HPH3" ENSG00000173889 "Polyhomeotic homolog 3" Q8NDX5 3 170086732-170181749 "Predicted intracellular proteins" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 48.0" "Cell type enhanced" "Detected in many" "Neutrophil progenitors: 498.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039162, HPA062031" Approved Supported Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 40: Non-specific - Mixed function" "Cluster 16: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 14 Nucleoplasm "HPA039162: , HPA062031: " "unprognostic (6.02e-2)" "unprognostic (5.48e-2)" "unprognostic (3.43e-1)" "unprognostic (2.91e-2)" "unprognostic (1.53e-1)" "unprognostic (1.15e-1)" "unprognostic (2.22e-1)" "unprognostic (2.94e-2)" "unprognostic (1.60e-1)" "potential prognostic unfavorable (2.22e-4)" "validated prognostic favorable (6.57e-4)" "validated prognostic favorable (4.60e-5)" "unprognostic (7.08e-2)" "unprognostic (1.56e-2)" "unprognostic (1.22e-1)" "unprognostic (2.83e-1)" "unprognostic (2.40e-1)" "unprognostic (6.56e-3)" "unprognostic (8.77e-2)" "unprognostic (8.66e-2)" "potential prognostic unfavorable (9.40e-4)" "potential prognostic unfavorable (6.12e-5)" "unprognostic (3.41e-3)" "unprognostic (1.60e-2)" "unprognostic (1.74e-3)" "unprognostic (4.12e-2)" "unprognostic (1.71e-2)" "unprognostic (1.57e-1)" "unprognostic (2.01e-1)" "unprognostic (1.61e-2)" "unprognostic (3.38e-1)" PHETA1 "FAM109A, FLJ32356, IPIP27A, SES1" ENSG00000198324 "PH domain containing endocytic trafficking adaptor 1" Q8N4B1 12 111360651-111369121 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 23.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 25.0;Colonocytes: 26.2;Early spermatids: 57.6;Enterocytes: 56.4;Esophageal apical cells: 23.3;Foveolar cells: 43.7;Mucous neck cells: 34.8;Pancreatic acinar cells: 23.2;Parietal cells: 23.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 3.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 19: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 1: Enterocytes - Absorption and Digestion" 21 "unprognostic (1.47e-1)" "unprognostic (7.24e-2)" "unprognostic (6.50e-3)" "unprognostic (7.78e-2)" "unprognostic (8.82e-2)" "unprognostic (1.27e-1)" "unprognostic (2.56e-1)" "unprognostic (2.68e-2)" "unprognostic (4.21e-1)" "potential prognostic unfavorable (6.03e-4)" "unprognostic (2.58e-2)" "unprognostic (2.03e-2)" "unprognostic (2.75e-3)" "unprognostic (1.15e-2)" "unprognostic (1.28e-3)" "unprognostic (2.91e-2)" "unprognostic (1.83e-1)" "unprognostic (1.87e-2)" "unprognostic (1.28e-2)" "unprognostic (1.68e-1)" "unprognostic (2.49e-1)" "unprognostic (1.47e-1)" "unprognostic (2.14e-1)" "unprognostic (1.04e-1)" "unprognostic (1.13e-1)" "unprognostic (3.01e-1)" "unprognostic (2.94e-1)" "unprognostic (9.83e-2)" "unprognostic (3.50e-1)" PHETA2 "DKFZp686J07229, FAM109B, IPIP27B, SES2" ENSG00000177096 "PH domain containing endocytic trafficking adaptor 2" Q6ICB4 22 42074248-42079438 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Gastric chief cells: 2.2;Microglia: 2.6;pDCs: 3.1;Platelets: 7.0;Tuft cells: 11.5" "Group enriched" "Detected in some" 4 "central nervous system macrophage: 3.0;endothelial cell: 4.2;fibroblast: 9.1;pericyte: 6.6;vascular associated smooth muscle cell: 4.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 20.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Liver - Vascular endothelial cells, Spleen - Fibroblasts_1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA000647 Uncertain NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 60: Stomach - Digestion" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 22: Non-specific - Basic cellular functions" 10 "HPA000647: " "unprognostic (3.56e-2)" "unprognostic (4.84e-2)" "unprognostic (9.15e-2)" "unprognostic (2.23e-1)" "unprognostic (3.83e-1)" "unprognostic (1.56e-3)" "unprognostic (3.05e-3)" "unprognostic (1.81e-3)" "unprognostic (7.16e-2)" "unprognostic (3.37e-1)" "unprognostic (1.55e-1)" "unprognostic (4.54e-3)" "unprognostic (7.08e-2)" "unprognostic (6.39e-2)" "unprognostic (8.00e-2)" "unprognostic (7.22e-2)" "unprognostic (4.28e-1)" "unprognostic (2.87e-1)" "unprognostic (3.16e-2)" "unprognostic (4.75e-2)" "unprognostic (2.02e-1)" "unprognostic (7.42e-3)" "unprognostic (2.58e-1)" "unprognostic (8.18e-2)" "unprognostic (1.56e-2)" "unprognostic (2.00e-1)" "unprognostic (1.19e-1)" "unprognostic (3.64e-1)" "unprognostic (1.68e-1)" PHEX "HPDR, HPDR1, HYP, HYP1, PEX, XLH" ENSG00000102174 "Phosphate regulating endopeptidase X-linked" P78562 X 22032325-22494713 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Biomineralization "Hydrolase, Metalloprotease, Protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "ovary: 4.8" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 54.5;Endometrial luminal cells: 47.0;Ependymal cells: 53.4;Granulosa cells: 43.0;Myonuclei: 69.1;Myosatellite cells: 95.6;pDCs: 334.8;Retinal horizontal cells: 72.1" "Cell type enhanced" "Detected in many" "astrocyte: 32.1;Bergmann glia: 32.5;ependymal cell: 67.3" "Cancer enriched" "Detected in some" 4 "Thyroid Carcinoma (TCGA): 8.9" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 27 "plasmacytoid DC: 5.8" "Lineage enriched" "Detected in single" 27 "dendritic cells: 5.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA078754 Approved "Vesicles,Plasma membrane" NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 75: Ovary - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 1 "Vesicles, Plasma membrane" "HPA078754: " "unprognostic (3.32e-2)" "unprognostic (3.63e-1)" "unprognostic (1.20e-1)" "unprognostic (6.20e-2)" "unprognostic (5.55e-2)" "unprognostic (1.38e-1)" "unprognostic (8.40e-2)" "unprognostic (3.05e-2)" "unprognostic (2.89e-2)" "unprognostic (3.11e-3)" PHF1 "MTF2L2, PCL1, TDRD19C" ENSG00000112511 "PHD finger protein 1" O43189 6 33410399-33416453 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 30.2;Bergmann glia: 31.7;Brain inhibitory neurons: 29.6;Late spermatids: 115.0;Oligodendrocyte progenitor cells: 31.1;Other brain neurons: 34.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031038, HPA076579" Approved Supported Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 30: White matter - Myelination" "Cluster 28: Non-specific - Nuclear processes" "Cluster 102: Non-specific - Mixed function" 76 Nucleoplasm "HPA031038: , HPA076579: " "unprognostic (2.60e-1)" "unprognostic (2.36e-1)" "unprognostic (3.04e-1)" "unprognostic (1.02e-2)" "unprognostic (3.21e-1)" "unprognostic (3.24e-1)" "unprognostic (1.61e-1)" "unprognostic (1.70e-1)" "unprognostic (8.78e-2)" "unprognostic (8.87e-2)" "potential prognostic favorable (4.63e-4)" "unprognostic (5.31e-1)" "unprognostic (2.04e-2)" "unprognostic (1.35e-1)" "unprognostic (3.87e-1)" "unprognostic (6.07e-2)" "unprognostic (1.81e-1)" "unprognostic (1.71e-2)" "unprognostic (2.52e-1)" "unprognostic (2.45e-1)" "unprognostic (8.69e-2)" "unprognostic (6.80e-3)" "unprognostic (4.55e-2)" "unprognostic (2.37e-1)" "unprognostic (7.57e-2)" "unprognostic (5.27e-2)" "unprognostic (3.20e-1)" "unprognostic (1.40e-1)" "unprognostic (3.71e-1)" "unprognostic (3.59e-2)" "unprognostic (2.97e-2)" PHF10 "BAF45a, FLJ10975, SMARCG4, XAP135" ENSG00000130024 "PHD finger protein 10" Q8WUB8 6 169703902-169725566 "Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 188.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055649 Supported Supported Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 103: Non-specific - Basic cellular processes" 52 Nucleoplasm "HPA055649: " "unprognostic (1.08e-1)" "unprognostic (1.82e-3)" "unprognostic (2.37e-2)" "unprognostic (3.15e-1)" "unprognostic (1.80e-1)" "unprognostic (1.03e-1)" "unprognostic (9.77e-3)" "unprognostic (2.42e-1)" "unprognostic (5.84e-2)" "unprognostic (7.75e-2)" "unprognostic (1.69e-3)" "unprognostic (1.00e-2)" "unprognostic (1.52e-1)" "potential prognostic unfavorable (1.11e-4)" "unprognostic (5.29e-3)" "unprognostic (4.59e-2)" "unprognostic (3.87e-1)" "unprognostic (4.08e-2)" "unprognostic (1.18e-1)" "unprognostic (2.07e-1)" "unprognostic (4.14e-2)" "unprognostic (4.36e-3)" "unprognostic (5.12e-2)" "unprognostic (1.45e-1)" "unprognostic (1.22e-3)" "unprognostic (7.58e-2)" "unprognostic (2.94e-1)" "unprognostic (1.04e-1)" "unprognostic (6.07e-2)" "unprognostic (1.62e-1)" "unprognostic (1.89e-1)" PHF11 "BCAP, IGER, NY-REN-34" ENSG00000136147 "PHD finger protein 11" Q9UIL8 13 49495610-49528981 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA016566 Supported "Nucleoplasm,Nuclear membrane" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 9: T-cells - Adaptive immunity: Regulation" 4 Nucleoplasm "Nuclear membrane" "HPA016566: " "unprognostic (7.96e-3)" "unprognostic (2.12e-1)" "unprognostic (1.29e-1)" "unprognostic (6.98e-2)" "unprognostic (2.59e-2)" "unprognostic (2.51e-2)" "unprognostic (5.75e-3)" "unprognostic (1.16e-2)" "unprognostic (1.02e-1)" "unprognostic (1.06e-1)" "unprognostic (1.75e-3)" "unprognostic (5.22e-2)" "unprognostic (1.49e-1)" "unprognostic (1.85e-1)" "unprognostic (1.13e-1)" "unprognostic (9.16e-2)" "unprognostic (3.56e-2)" "unprognostic (3.28e-2)" "unprognostic (6.98e-2)" "unprognostic (2.10e-2)" "unprognostic (2.80e-1)" "unprognostic (4.56e-2)" "unprognostic (1.15e-3)" "unprognostic (1.34e-1)" "unprognostic (3.18e-1)" "unprognostic (3.41e-2)" "unprognostic (1.43e-1)" "unprognostic (1.06e-1)" "unprognostic (2.93e-2)" "unprognostic (2.16e-2)" "unprognostic (2.10e-1)" PHF12 "KIAA1523, PF1" ENSG00000109118 "PHD finger protein 12" Q96QT6 17 28905250-28951771 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 343.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 40.4" "Lineage enriched" "Detected in all" 5 "granulocytes: 40.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021410, HPA021452" Approved Enhanced Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 49: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" 20 Nucleoplasm "HPA021410: , HPA021452: " "potential prognostic favorable (3.47e-4)" "unprognostic (1.04e-1)" "unprognostic (1.14e-1)" "unprognostic (3.85e-2)" "unprognostic (1.17e-1)" "unprognostic (2.69e-2)" "unprognostic (2.87e-1)" "unprognostic (5.35e-2)" "unprognostic (3.42e-2)" "unprognostic (6.22e-3)" "unprognostic (6.94e-2)" "unprognostic (9.57e-2)" "unprognostic (2.99e-1)" "unprognostic (1.32e-2)" "unprognostic (5.71e-2)" "unprognostic (1.76e-1)" "unprognostic (4.21e-2)" "unprognostic (2.38e-1)" "potential prognostic favorable (5.54e-4)" "unprognostic (2.03e-2)" "unprognostic (1.24e-1)" "unprognostic (9.27e-2)" "unprognostic (1.79e-2)" "unprognostic (2.76e-1)" "unprognostic (6.10e-3)" "unprognostic (1.27e-1)" "unprognostic (6.39e-3)" "unprognostic (7.04e-2)" "unprognostic (2.85e-1)" "unprognostic (1.17e-1)" "unprognostic (1.83e-1)" PHF13 MGC43399 ENSG00000116273 "PHD finger protein 13" Q86YI8 1 6613731-6624030 "Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Chromatin regulator" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 45.3;Undifferentiated spermatogonia: 53.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast myoepithelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026830 Uncertain NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 21: Testis - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 37: Non-specific - mRNA processing" "Cluster 26: Keratinocytes - Keratinization" "HPA026830: " "unprognostic (5.90e-2)" "unprognostic (3.16e-1)" "unprognostic (5.95e-2)" "unprognostic (6.05e-2)" "unprognostic (1.62e-1)" "unprognostic (2.29e-1)" "unprognostic (3.56e-1)" "unprognostic (3.82e-2)" "unprognostic (6.47e-2)" "unprognostic (2.22e-2)" "unprognostic (2.42e-2)" "unprognostic (1.11e-2)" "unprognostic (3.47e-1)" "validated prognostic unfavorable (1.08e-4)" "validated prognostic unfavorable (2.60e-4)" "unprognostic (1.52e-2)" "unprognostic (1.20e-3)" "unprognostic (2.04e-2)" "unprognostic (3.70e-1)" "unprognostic (8.23e-2)" "unprognostic (8.07e-2)" "unprognostic (1.67e-2)" "unprognostic (1.82e-1)" "unprognostic (1.33e-1)" "unprognostic (1.37e-1)" "unprognostic (6.94e-3)" "unprognostic (2.49e-1)" "unprognostic (1.42e-1)" "unprognostic (2.03e-2)" "unprognostic (2.98e-2)" "unprognostic (1.98e-1)" PHF14 KIAA0783 ENSG00000106443 "PHD finger protein 14" O94880 7 10973336-11169623 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000538, HPA017376" Supported Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 37: Neurons - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 27 Vesicles "Nucleoplasm, Cytosol" "HPA000538: , HPA017376: " "unprognostic (1.57e-1)" "unprognostic (8.81e-2)" "unprognostic (6.05e-3)" "unprognostic (3.19e-1)" "unprognostic (1.23e-2)" "unprognostic (2.46e-1)" "unprognostic (3.35e-1)" "unprognostic (8.72e-2)" "unprognostic (1.92e-1)" "potential prognostic unfavorable (2.99e-4)" "potential prognostic favorable (9.89e-6)" "unprognostic (2.07e-2)" "unprognostic (2.61e-1)" "unprognostic (2.20e-3)" "unprognostic (1.75e-3)" "unprognostic (1.04e-3)" "unprognostic (3.79e-2)" "unprognostic (6.84e-3)" "unprognostic (2.05e-1)" "unprognostic (1.86e-1)" "unprognostic (1.21e-3)" "unprognostic (1.47e-3)" "unprognostic (2.70e-2)" "unprognostic (5.21e-2)" "unprognostic (2.94e-1)" "unprognostic (4.61e-2)" "unprognostic (1.68e-2)" "unprognostic (1.63e-1)" "unprognostic (2.36e-1)" "unprognostic (1.90e-2)" "unprognostic (1.73e-1)" PHF19 "DKFZP727G051, MTF2L1, PCL3, TDRD19B" ENSG00000119403 "PHD finger protein 19" Q5T6S3 9 120855651-120894896 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 63.3;Hofbauer cells: 45.8;Megakaryocyte progenitors: 53.0;Monocyte progenitors: 81.5;monocytes: 60.5;Plasma cells: 41.8" "Cell type enhanced" "Detected in all" "leukocyte: 27.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "intermediate monocyte: 58.2;non-classical monocyte: 79.9;T-reg: 31.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 11: White matter - Signal transduction" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Cell proliferation" 56 "unprognostic (2.17e-1)" "unprognostic (4.62e-2)" "unprognostic (3.09e-1)" "unprognostic (2.54e-2)" "unprognostic (8.57e-3)" "unprognostic (2.26e-2)" "unprognostic (7.76e-2)" "unprognostic (1.82e-1)" "unprognostic (5.46e-2)" "potential prognostic unfavorable (5.52e-4)" "potential prognostic unfavorable (2.88e-4)" "unprognostic (3.17e-2)" "unprognostic (1.81e-1)" "validated prognostic unfavorable (2.76e-5)" "validated prognostic unfavorable (3.45e-6)" "unprognostic (1.26e-3)" "potential prognostic unfavorable (9.49e-7)" "unprognostic (2.95e-1)" "unprognostic (3.68e-1)" "unprognostic (2.50e-1)" "unprognostic (3.48e-2)" "unprognostic (9.72e-2)" "unprognostic (3.97e-3)" "unprognostic (1.24e-1)" "unprognostic (5.98e-2)" "unprognostic (2.26e-1)" "unprognostic (4.43e-2)" "unprognostic (8.48e-2)" "unprognostic (1.65e-1)" "unprognostic (7.55e-3)" "unprognostic (1.76e-2)" PHF2 "CENP-35, JHDM1E, KDM7C, KIAA0662" ENSG00000197724 "PHD finger protein 2" O75151 9 93576584-93679587 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Late spermatids: 1087.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010831 Approved Supported "Nucleoplasm,Nucleoli rim" NA No "Cluster 35: Neutrophils - Protein binding" "Cluster 24: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 8 "Nucleoli rim" Nucleoplasm "HPA010831: " "unprognostic (3.89e-2)" "unprognostic (1.12e-1)" "unprognostic (1.61e-1)" "unprognostic (2.79e-1)" "unprognostic (1.71e-2)" "unprognostic (2.85e-2)" "unprognostic (1.98e-1)" "potential prognostic favorable (1.65e-4)" "unprognostic (2.45e-1)" "unprognostic (6.36e-2)" "potential prognostic favorable (7.73e-4)" "unprognostic (2.27e-3)" "unprognostic (3.42e-2)" "unprognostic (1.36e-1)" "unprognostic (1.40e-1)" "unprognostic (1.55e-1)" "unprognostic (4.44e-2)" "unprognostic (1.05e-1)" "unprognostic (1.00e-2)" "unprognostic (7.39e-2)" "unprognostic (2.03e-1)" "unprognostic (9.83e-3)" "unprognostic (4.15e-1)" "unprognostic (9.64e-2)" "unprognostic (3.14e-1)" "unprognostic (1.67e-1)" "unprognostic (1.17e-1)" "unprognostic (1.10e-1)" "unprognostic (1.54e-1)" "unprognostic (2.08e-1)" "unprognostic (5.72e-2)" PHF20 "C20orf104, dJ1121G12.1, TDRD20A" ENSG00000025293 "PHD finger protein 20" Q9BVI0 20 35771974-35950370 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 1081.5;Mast cells: 1108.7;Neutrophils: 1233.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029619, HPA029620, HPA029621" Approved Supported "Nucleoplasm,Nuclear membrane,Golgi apparatus,Cytosol" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 38 Nucleoplasm "Nuclear membrane, Golgi apparatus, Cytosol" "HPA029619: , HPA029620: , HPA029621: " "unprognostic (3.90e-1)" "unprognostic (1.79e-3)" "unprognostic (1.70e-2)" "unprognostic (8.44e-3)" "unprognostic (1.27e-1)" "unprognostic (3.31e-2)" "unprognostic (2.43e-1)" "unprognostic (6.39e-2)" "unprognostic (1.81e-1)" "potential prognostic unfavorable (6.41e-4)" "potential prognostic favorable (5.40e-5)" "unprognostic (2.75e-1)" "unprognostic (1.43e-1)" "unprognostic (2.08e-3)" "unprognostic (1.07e-2)" "unprognostic (1.61e-1)" "unprognostic (9.40e-2)" "unprognostic (4.93e-2)" "unprognostic (7.77e-2)" "potential prognostic unfavorable (2.60e-4)" "unprognostic (4.93e-3)" "unprognostic (1.35e-1)" "unprognostic (3.45e-3)" "unprognostic (7.49e-2)" "unprognostic (1.37e-3)" "unprognostic (1.09e-2)" "unprognostic (1.36e-1)" "unprognostic (1.88e-1)" "unprognostic (1.82e-1)" "unprognostic (1.73e-2)" "unprognostic (3.88e-1)" PHF20L1 "CGI-72, FLJ13649, FLJ21615, MGC64923, TDRD20B" ENSG00000129292 "PHD finger protein 20 like 1" A8MW92 8 132775358-132848807 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 540.0;Neutrophils: 1312.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025060, HPA028417" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 16: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 36 "Nucleoplasm, Plasma membrane" "HPA025060: , HPA028417: " "unprognostic (3.74e-1)" "unprognostic (1.12e-2)" "unprognostic (2.52e-1)" "unprognostic (2.24e-1)" "unprognostic (1.84e-1)" "unprognostic (5.43e-2)" "unprognostic (1.16e-1)" "unprognostic (8.64e-3)" "unprognostic (2.50e-1)" "potential prognostic unfavorable (6.39e-4)" "potential prognostic favorable (8.49e-4)" "unprognostic (3.37e-3)" "unprognostic (5.50e-3)" "unprognostic (5.21e-2)" "unprognostic (7.98e-2)" "unprognostic (4.10e-2)" "unprognostic (1.23e-1)" "unprognostic (3.44e-2)" "unprognostic (5.90e-2)" "unprognostic (1.27e-1)" "unprognostic (7.10e-2)" "unprognostic (3.62e-2)" "potential prognostic unfavorable (6.91e-5)" "unprognostic (6.83e-2)" "unprognostic (1.18e-1)" "unprognostic (3.89e-2)" "unprognostic (1.80e-2)" "unprognostic (3.28e-1)" "unprognostic (2.65e-1)" "unprognostic (6.43e-2)" "unprognostic (4.89e-2)" PHF21A "BHC80, BM-006, KIAA1696" ENSG00000135365 "PHD finger protein 21A" Q96BD5 11 45929319-46121454 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Repressor" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "Neutrophils: 3250.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pancreas - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023253, HPA023580" Uncertain Supported Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 65: Brain - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" 39 Nucleoplasm "HPA023253: , HPA023580: " "unprognostic (2.69e-2)" "unprognostic (1.21e-1)" "unprognostic (1.62e-1)" "unprognostic (6.52e-3)" "unprognostic (8.83e-2)" "unprognostic (4.38e-2)" "unprognostic (1.97e-1)" "unprognostic (4.00e-2)" "unprognostic (1.56e-1)" "unprognostic (2.60e-2)" "unprognostic (3.08e-2)" "unprognostic (5.30e-2)" "unprognostic (2.85e-1)" "potential prognostic unfavorable (9.31e-6)" "unprognostic (1.86e-1)" "unprognostic (2.30e-1)" "unprognostic (1.16e-3)" "unprognostic (2.53e-2)" "unprognostic (1.91e-1)" "unprognostic (2.57e-3)" "unprognostic (4.92e-2)" "unprognostic (4.05e-2)" "potential prognostic unfavorable (2.19e-4)" "unprognostic (1.03e-1)" "unprognostic (5.64e-2)" "unprognostic (2.22e-1)" "unprognostic (2.16e-1)" "unprognostic (1.93e-2)" "unprognostic (3.33e-1)" "unprognostic (7.31e-2)" "unprognostic (8.38e-2)" PHF21B "BHC80L, FLJ34161, PHF4" ENSG00000056487 "PHD finger protein 21B" Q96EK2 22 44881162-45010005 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 8.4;pituitary gland: 18.0" "Cell type enhanced" "Detected in many" "Astrocytes: 229.8;Bergmann glia: 306.5;Cone photoreceptor cells: 176.0;Corticotrophs: 308.3;Distal convoluted tubule cells: 183.2;Gonadotrophs: 183.9;Lactotrophs: 305.2;Podocytes: 265.6;Prostatic glandular cells: 134.6;Retinal horizontal cells: 168.3;Rod photoreceptor cells: 175.4;Somatotrophs: 351.1;Thyrotrophs: 219.4" "Cell type enhanced" "Detected in many" "astrocyte: 261.2;Bergmann glia: 294.1" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 5.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "Neuroblastoma: 42.2" "Breast - Breast glandular cells, Colon - Enteric glia cells, Pancreas - Alpha cells, Prostate - Prostate glandular cells, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA053834, HPA074665" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 21: Testis - Mixed function" "Cluster 46: Brainstem - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 3 "Nucleoplasm, Nucleoli fibrillar center" Cytosol "HPA053834: , HPA074665: " "unprognostic (2.19e-1)" "unprognostic (7.53e-2)" "potential prognostic favorable (3.20e-5)" "unprognostic (2.73e-3)" "unprognostic (1.71e-1)" "unprognostic (3.50e-1)" PHF23 "FLJ16355, MGC2941" ENSG00000040633 "PHD finger protein 23" Q9BUL5 17 7235029-7239722 "Disease related genes, Predicted intracellular proteins" "Autophagy, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 192.4;Syncytiotrophoblasts: 93.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052410, HPA077075" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 42: Non-specific - Unknown function" "Cluster 84: Apical squamous epithelium - Cornification" 11 Nucleoplasm Cytosol "HPA052410: , HPA077075: " "unprognostic (5.77e-2)" "unprognostic (2.19e-1)" "unprognostic (3.74e-1)" "potential prognostic unfavorable (4.05e-4)" "unprognostic (1.29e-1)" "unprognostic (2.81e-1)" "unprognostic (1.76e-1)" "unprognostic (5.88e-3)" "unprognostic (5.16e-2)" "unprognostic (2.59e-2)" "potential prognostic favorable (1.71e-4)" "unprognostic (4.00e-2)" "unprognostic (1.80e-2)" "potential prognostic unfavorable (9.48e-4)" "unprognostic (9.75e-2)" "unprognostic (1.91e-3)" "unprognostic (2.79e-1)" "unprognostic (2.90e-1)" "unprognostic (2.66e-2)" "unprognostic (4.91e-2)" "unprognostic (1.79e-1)" "unprognostic (5.78e-3)" "unprognostic (7.42e-2)" "unprognostic (1.77e-1)" "unprognostic (1.43e-1)" "unprognostic (1.97e-2)" "unprognostic (1.21e-1)" "unprognostic (3.03e-1)" "unprognostic (2.93e-1)" "unprognostic (2.41e-2)" "unprognostic (1.55e-3)" PHF24 KIAA1045 ENSG00000122733 "PHD finger protein 24" Q9UPV7 9 34957608-34982544 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 48.2;testis: 15.6" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 20.2;Brain inhibitory neurons: 16.4;Cone photoreceptor cells: 47.6;Epicardial cells: 20.5;Late spermatids: 10.6;Müller glia: 13.8;Other brain neurons: 14.5;Retinal amacrine cells: 15.2;Sertoli cells: 50.5" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 2.5;Testicular Germ Cell Tumor (TCGA): 3.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 20 "neutrophil: 2.0" "Lineage enriched" "Detected in single" 20 "granulocytes: 2.0" "Not detected" "Not detected" "Colon - Enteric glia cells, Prostate - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020974 Approved NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 50: Lymphoma - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" 4 "HPA020974: " "unprognostic (2.09e-2)" "unprognostic (6.16e-2)" "unprognostic (1.51e-1)" "unprognostic (3.78e-2)" "unprognostic (3.84e-2)" "unprognostic (2.22e-1)" PHF3 ENSG00000118482 "PHD finger protein 3" Q92576 6 63635802-63779336 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024676, HPA025763" Approved Approved Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" 15 Nucleoplasm "HPA024676: , HPA025763: " "unprognostic (1.65e-3)" "unprognostic (3.39e-2)" "unprognostic (2.70e-1)" "unprognostic (2.24e-2)" "unprognostic (7.94e-2)" "unprognostic (3.06e-2)" "unprognostic (1.34e-2)" "unprognostic (7.03e-2)" "unprognostic (1.19e-1)" "unprognostic (4.04e-2)" "validated prognostic favorable (1.87e-6)" "validated prognostic favorable (7.43e-6)" "unprognostic (7.04e-2)" "unprognostic (3.03e-2)" "unprognostic (1.75e-1)" "unprognostic (5.70e-2)" "unprognostic (1.38e-1)" "unprognostic (2.86e-1)" "unprognostic (2.82e-1)" "unprognostic (1.86e-1)" "unprognostic (4.88e-2)" "unprognostic (8.67e-3)" "unprognostic (1.26e-2)" "unprognostic (3.43e-1)" "unprognostic (8.39e-3)" "unprognostic (1.92e-2)" "unprognostic (2.12e-1)" "unprognostic (3.08e-1)" "unprognostic (5.04e-1)" "unprognostic (7.77e-2)" "unprognostic (3.35e-1)" PHF5A "bK223H9.2, INI, MGC1346, Rds3, SAP14b, SF3b14b, SF3B7" ENSG00000100410 "PHD finger protein 5A" Q7RTV0 22 41459717-41468692 "Essential proteins, Predicted intracellular proteins, Transcription factors" "mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Activator, DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 109.1;Differentiating spermatogonia: 106.0;Esophageal basal cells: 110.7;Extravillous trophoblasts: 131.1;Migrating cytotrophoblasts: 119.6;Syncytiotrophoblasts: 127.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028885 Supported Enhanced Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 66: Non-specific - Mitochondria" "Cluster 17: Non-specific - RNA processing" 61 Nucleoplasm "HPA028885: " "unprognostic (1.45e-2)" "unprognostic (4.80e-1)" "unprognostic (2.41e-2)" "unprognostic (6.64e-3)" "unprognostic (1.53e-1)" "unprognostic (1.42e-1)" "unprognostic (1.88e-1)" "unprognostic (1.16e-1)" "unprognostic (2.33e-2)" "unprognostic (1.54e-2)" "potential prognostic favorable (2.89e-5)" "unprognostic (1.15e-1)" "unprognostic (2.96e-1)" "validated prognostic unfavorable (8.83e-9)" "validated prognostic unfavorable (6.21e-4)" "potential prognostic unfavorable (2.13e-4)" "unprognostic (7.77e-2)" "unprognostic (1.04e-2)" "unprognostic (1.47e-3)" "unprognostic (1.26e-1)" "unprognostic (1.62e-1)" "unprognostic (3.78e-3)" "unprognostic (3.35e-1)" "unprognostic (8.89e-2)" "unprognostic (5.75e-3)" "unprognostic (2.62e-1)" "unprognostic (3.43e-2)" "unprognostic (2.18e-2)" "unprognostic (1.70e-1)" "unprognostic (4.15e-2)" "unprognostic (3.48e-1)" PHF6 "BFLS, BORJ, CENP-31, KIAA1823, MGC14797" ENSG00000156531 "PHD finger protein 6" Q8IWS0 X 134373288-134428791 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant, Epilepsy, Hypotrichosis, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 123.4;Granulosa cells: 133.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001023 Enhanced Supported Nucleoplasm,Nucleoli NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 36: Non-specific - mRNA processing" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 12 "Nucleoplasm, Nucleoli" "HPA001023: " "unprognostic (4.56e-2)" "unprognostic (7.28e-3)" "unprognostic (3.50e-1)" "unprognostic (2.08e-1)" "unprognostic (1.39e-1)" "unprognostic (2.94e-1)" "unprognostic (4.46e-2)" "unprognostic (1.28e-3)" "unprognostic (2.45e-2)" "unprognostic (1.18e-2)" "potential prognostic favorable (6.77e-4)" "unprognostic (3.30e-2)" "unprognostic (1.00e-1)" "potential prognostic unfavorable (2.49e-4)" "unprognostic (5.59e-2)" "unprognostic (8.52e-3)" "unprognostic (2.12e-2)" "unprognostic (7.79e-3)" "unprognostic (2.07e-1)" "unprognostic (1.79e-1)" "unprognostic (5.99e-3)" "unprognostic (8.26e-3)" "unprognostic (3.12e-3)" "unprognostic (6.78e-2)" "unprognostic (2.32e-2)" "unprognostic (6.45e-2)" "unprognostic (3.93e-2)" "unprognostic (1.39e-1)" "unprognostic (9.71e-2)" "unprognostic (3.48e-2)" "unprognostic (6.42e-2)" PHF7 "HSPC226, NYD-SP6" ENSG00000010318 "PHD finger protein 7" Q9BWX1 3 52410660-52423641 "Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 213 "testis: 1149.0" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 680.6;Early spermatids: 2532.2;Late primary spermatocytes: 3496.6;Late spermatids: 12449.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 12.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA036283, HPA070305" Enhanced Supported "Nucleoplasm,Nuclear speckles,Golgi apparatus" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 6: Testis - Spermatogenesis" "Cluster 37: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 5 "Nucleoplasm, Nuclear speckles" "Golgi apparatus" "HPA036283: , HPA070305: " "unprognostic (2.35e-1)" "potential prognostic favorable (6.51e-4)" "unprognostic (9.64e-2)" "unprognostic (1.00e-1)" "unprognostic (1.80e-1)" "unprognostic (1.36e-1)" "unprognostic (1.54e-2)" "unprognostic (1.31e-1)" "unprognostic (1.14e-3)" "unprognostic (1.06e-1)" "unprognostic (5.39e-2)" "unprognostic (7.69e-2)" "potential prognostic favorable (1.40e-5)" "unprognostic (1.01e-1)" "unprognostic (9.32e-2)" "unprognostic (1.23e-1)" "unprognostic (2.24e-2)" "unprognostic (2.36e-1)" "unprognostic (1.19e-1)" "unprognostic (1.58e-1)" "unprognostic (9.43e-2)" "unprognostic (2.92e-3)" "unprognostic (2.00e-2)" "unprognostic (4.83e-3)" "unprognostic (4.05e-1)" "unprognostic (2.05e-1)" "unprognostic (5.29e-3)" "unprognostic (3.02e-1)" "unprognostic (1.48e-1)" "unprognostic (7.53e-2)" "unprognostic (1.12e-1)" PHF8 "JHDM1F, KDM7B, KIAA1111, ZNF422" ENSG00000172943 "PHD finger protein 8" Q9UPP1 X 53936676-54048958 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation" "Activator, Chromatin regulator, Dioxygenase, Oxidoreductase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Prostate - Prostate basal glandular cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038779, HPA062015" Approved Supported Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 22: Epididymis - Mixed function" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 26 Nucleoplasm "HPA038779: , HPA062015: " "unprognostic (8.17e-3)" "unprognostic (2.85e-2)" "unprognostic (3.31e-2)" "unprognostic (2.16e-1)" "unprognostic (1.38e-1)" "unprognostic (6.44e-2)" "unprognostic (1.08e-1)" "unprognostic (9.16e-2)" "unprognostic (1.88e-1)" "unprognostic (8.21e-2)" "unprognostic (6.07e-3)" "unprognostic (2.26e-3)" "unprognostic (1.40e-2)" "unprognostic (1.74e-1)" "unprognostic (5.22e-2)" "unprognostic (8.67e-2)" "unprognostic (5.68e-2)" "unprognostic (9.85e-3)" "unprognostic (2.63e-2)" "unprognostic (8.35e-2)" "unprognostic (4.60e-2)" "unprognostic (2.36e-1)" "unprognostic (6.89e-2)" "unprognostic (5.14e-2)" "unprognostic (6.98e-2)" "unprognostic (4.31e-2)" "unprognostic (3.06e-2)" "unprognostic (3.96e-1)" "unprognostic (9.90e-2)" "unprognostic (8.22e-2)" "unprognostic (1.17e-1)" PHGDH "PDG, PGDH, SERA" ENSG00000092621 "Phosphoglycerate dehydrogenase" O43175 1 119648411-119744218 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Serine biosynthesis" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cholangiocytes: 182.6;Epididymal principal cells: 269.4;Esophageal basal cells: 209.4;Lacrimal acinar cells: 199.3;Late spermatids: 198.0;Salivary acinar cells: 140.1" "Cell type enhanced" "Detected in many" "astrocyte: 54.4;Bergmann glia: 61.5;oligodendrocyte: 56.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD8 T-cell: 25.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Skeletal muscle - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003681, HPA021241, HPA024031, CAB068216" Enhanced Approved "Nucleoplasm,Plasma membrane,Mitotic spindle,Primary cilium,Cytosol" Yes No 490000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 70: Non-specific - Protein processing" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" 57 "Nucleoplasm, Plasma membrane, Cytosol" "Mitotic spindle, Primary cilium" "CAB003681: , CAB068216: , HPA021241: , HPA024031: " "unprognostic (9.51e-2)" "unprognostic (2.45e-1)" "unprognostic (1.34e-1)" "unprognostic (2.25e-1)" "unprognostic (2.52e-2)" "unprognostic (8.33e-2)" "unprognostic (2.37e-2)" "unprognostic (3.19e-1)" "unprognostic (4.85e-2)" "unprognostic (1.37e-3)" "unprognostic (5.79e-2)" "unprognostic (1.12e-1)" "unprognostic (5.12e-3)" "unprognostic (3.46e-3)" "unprognostic (5.01e-2)" "unprognostic (5.73e-2)" "unprognostic (1.03e-1)" "unprognostic (5.52e-3)" "unprognostic (4.16e-2)" "unprognostic (4.73e-3)" "unprognostic (2.90e-1)" "unprognostic (1.48e-2)" "unprognostic (4.48e-3)" "unprognostic (2.59e-2)" "unprognostic (1.93e-1)" "unprognostic (8.78e-2)" "unprognostic (1.99e-1)" "unprognostic (4.31e-2)" "unprognostic (1.50e-1)" "unprognostic (2.24e-1)" "unprognostic (3.56e-1)" PHGR1 ENSG00000233041 "Proline, histidine and glycine rich 1" C9JFL3 15 40351033-40356434 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in many" 15 "intestine: 2480.9" "Cell type enhanced" "Detected in some" "Colonocytes: 54118.6;Enteric transient amplifying cells: 8666.9;Enterocytes: 47339.7;Goblet cells: 13186.1;Neuroendocrine cells: 4016.6" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "Colon Adenocarcinoma (TCGA): 668.2;Rectum Adenocarcinoma (TCGA): 544.7;Stomach Adenocarcinoma (TCGA): 383.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 203.2;colorectal cancer: 705.6" "Breast - Breast glandular cells, Colon - Colon enterocytes, Stomach - Gastric mucous cells" HPA068787 Enhanced Approved Vesicles NA NA "Cluster 77: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" Vesicles "HPA068787: " "unprognostic (2.25e-1)" "unprognostic (3.07e-3)" "unprognostic (1.55e-3)" "unprognostic (3.41e-1)" "unprognostic (3.72e-2)" "unprognostic (3.02e-2)" "unprognostic (2.62e-2)" "unprognostic (3.93e-1)" "unprognostic (9.90e-2)" "unprognostic (2.09e-1)" "unprognostic (4.34e-2)" "unprognostic (1.44e-1)" "unprognostic (3.35e-2)" "unprognostic (1.59e-1)" "unprognostic (5.95e-2)" PHIP "BRWD2, DCAF14, FLJ20705, ndrp, WDR11" ENSG00000146247 "Pleckstrin homology domain interacting protein" Q8WWQ0 6 78934419-79078287 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019140, HPA019838" Approved Approved "Nucleoplasm,Nucleoli rim" NA NA "Cluster 32: Basophils - Transcription" "Cluster 40: Non-specific - Mixed function" "Cluster 25: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" 27 Nucleoplasm "Nucleoli rim" "HPA019140: , HPA019838: " "unprognostic (1.17e-1)" "unprognostic (1.29e-2)" "unprognostic (1.58e-1)" "unprognostic (2.78e-1)" "unprognostic (1.26e-1)" "unprognostic (2.53e-2)" "unprognostic (1.63e-1)" "unprognostic (3.29e-1)" "unprognostic (4.21e-3)" "unprognostic (1.33e-3)" "unprognostic (1.38e-1)" "unprognostic (9.55e-3)" "unprognostic (9.08e-2)" "unprognostic (2.42e-3)" "unprognostic (6.19e-2)" "unprognostic (1.75e-1)" "unprognostic (3.04e-1)" "unprognostic (8.31e-2)" "unprognostic (3.78e-2)" "unprognostic (2.78e-2)" "unprognostic (5.74e-3)" "unprognostic (8.25e-2)" "unprognostic (1.17e-2)" "unprognostic (2.59e-1)" "unprognostic (3.12e-2)" "unprognostic (1.23e-2)" "unprognostic (1.29e-1)" "unprognostic (2.64e-1)" "unprognostic (1.58e-1)" "unprognostic (3.55e-2)" "unprognostic (2.23e-2)" PHKA1 PHKA ENSG00000067177 "Phosphorylase kinase regulatory subunit alpha 1" P46020 X 72578814-72714319 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Calmodulin-binding, Muscle protein" "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "parathyroid gland: 30.1;skeletal muscle: 96.1;tongue: 83.3" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 147.7;Astrocytes: 153.7;Choroid plexus epithelial cells: 179.1;Gonadotrophs: 97.7;Lactotrophs: 123.5;Myonuclei: 181.8;Pituicytes/FSCs: 126.5;Retinal pigment epithelial cells: 170.5;Somatotrophs: 145.6;Thyrotrophs: 206.3" "Cell type enhanced" "Detected in all" "astrocyte: 187.6;choroid plexus epithelial cell: 151.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001081, HPA075355" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 19: Astrocytes - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 8 "Vesicles, Cytosol" "HPA001081: , HPA075355: " "unprognostic (2.15e-1)" "unprognostic (1.07e-2)" "unprognostic (2.76e-1)" "unprognostic (1.37e-1)" "unprognostic (2.02e-1)" "unprognostic (1.14e-2)" "unprognostic (1.24e-1)" "unprognostic (1.37e-1)" "unprognostic (6.89e-2)" "unprognostic (2.09e-2)" "unprognostic (2.76e-2)" "unprognostic (1.33e-1)" "unprognostic (2.76e-2)" "unprognostic (1.25e-1)" "unprognostic (2.47e-3)" "unprognostic (8.60e-3)" "unprognostic (4.88e-2)" "unprognostic (1.45e-1)" "unprognostic (2.89e-1)" "unprognostic (8.96e-2)" "unprognostic (2.42e-1)" "unprognostic (1.48e-1)" "unprognostic (2.13e-1)" "unprognostic (1.28e-1)" "unprognostic (5.19e-1)" "unprognostic (1.43e-1)" "unprognostic (3.12e-2)" "unprognostic (3.85e-1)" "unprognostic (9.81e-2)" "unprognostic (2.35e-1)" PHKA2 "PHK, PYK" ENSG00000044446 "Phosphorylase kinase regulatory subunit alpha 2" P46019 X 18892298-18984114 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" Calmodulin-binding "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 118.9;Sertoli cells: 161.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skin - Outer root sheath cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002912 Approved Approved Nucleoplasm NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 6: Non-specific - Immune response" "Cluster 36: Non-specific - mRNA processing" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 33 Nucleoplasm "HPA002912: " "unprognostic (2.14e-1)" "unprognostic (5.07e-3)" "unprognostic (7.81e-2)" "unprognostic (2.03e-1)" "unprognostic (9.58e-2)" "unprognostic (3.03e-1)" "unprognostic (1.05e-1)" "unprognostic (1.66e-3)" "unprognostic (2.49e-2)" "unprognostic (5.60e-3)" "potential prognostic favorable (3.70e-4)" "unprognostic (4.88e-2)" "unprognostic (2.03e-1)" "potential prognostic unfavorable (3.95e-6)" "unprognostic (1.16e-1)" "unprognostic (1.58e-1)" "unprognostic (4.12e-2)" "unprognostic (1.01e-1)" "unprognostic (1.22e-3)" "unprognostic (1.75e-1)" "unprognostic (1.39e-2)" "unprognostic (3.42e-2)" "unprognostic (1.86e-1)" "unprognostic (1.95e-1)" "unprognostic (4.66e-2)" "unprognostic (4.06e-2)" "unprognostic (2.65e-1)" "unprognostic (9.08e-2)" "unprognostic (1.57e-1)" "unprognostic (9.95e-2)" "unprognostic (1.80e-1)" PHKB ENSG00000102893 "Phosphorylase kinase regulatory subunit beta" Q93100 16 47461123-47701523 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" Calmodulin-binding "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 122.8" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Endothelial cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073380 Approved "Golgi apparatus" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Transcription" 16 "Golgi apparatus" "HPA073380: " "unprognostic (6.05e-2)" "potential prognostic unfavorable (8.26e-4)" "unprognostic (1.73e-1)" "unprognostic (3.15e-2)" "unprognostic (1.46e-1)" "unprognostic (1.57e-1)" "unprognostic (1.63e-1)" "unprognostic (6.58e-3)" "unprognostic (3.32e-2)" "unprognostic (3.46e-2)" "potential prognostic favorable (9.36e-6)" "unprognostic (5.83e-3)" "unprognostic (9.27e-2)" "unprognostic (5.97e-3)" "unprognostic (5.63e-3)" "unprognostic (2.20e-1)" "unprognostic (2.81e-1)" "unprognostic (3.44e-1)" "unprognostic (5.34e-2)" "unprognostic (3.91e-2)" "unprognostic (4.00e-2)" "unprognostic (8.26e-2)" "unprognostic (2.05e-1)" "unprognostic (1.42e-1)" "unprognostic (1.40e-2)" "unprognostic (1.38e-1)" "unprognostic (6.19e-2)" "unprognostic (3.37e-2)" "unprognostic (3.07e-1)" "potential prognostic unfavorable (1.83e-4)" "unprognostic (8.81e-3)" PHKG1 PHKG ENSG00000164776 "Phosphorylase kinase catalytic subunit gamma 1" Q16816 7 56080283-56092996 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism, Glycogen metabolism" "Calmodulin-binding, Kinase, Muscle protein, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 13 "skeletal muscle: 272.6;tongue: 165.8" "Group enriched" "Detected in many" 4 "Bergmann glia: 149.2;Myonuclei: 431.5" "Group enriched" "Detected in all" 4 "astrocyte: 62.4;Bergmann glia: 138.5;ependymal cell: 42.7" "Group enriched" "Detected in many" 12 "Glioblastoma Multiforme (TCGA): 53.1;Prostate Adenocarcinoma (TCGA): 20.4;Uterine Corpus Endometrial Carcinoma (TCGA): 27.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012057 Enhanced NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 44: Non-specific - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 1 "HPA012057: " "unprognostic (1.74e-1)" "unprognostic (2.29e-2)" "unprognostic (2.28e-1)" "unprognostic (2.08e-1)" "unprognostic (1.62e-1)" "unprognostic (1.74e-2)" "unprognostic (2.43e-2)" "unprognostic (8.97e-2)" "unprognostic (4.13e-2)" "unprognostic (7.25e-2)" "potential prognostic unfavorable (2.47e-4)" "unprognostic (1.67e-1)" PHKG2 ENSG00000156873 "Phosphorylase kinase catalytic subunit gamma 2" P15735 16 30748293-30761176 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism, Glycogen metabolism" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "testis: 123.9" "Cell type enriched" "Detected in all" 6 "Late spermatids: 2899.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065618, HPA068751" Supported Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 67: Testis - Mixed function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 54: Non-specific - Transcription" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 31 Cytosol "HPA065618: , HPA068751: " "unprognostic (1.28e-1)" "unprognostic (3.63e-2)" "unprognostic (6.63e-2)" "unprognostic (1.49e-1)" "unprognostic (1.65e-1)" "unprognostic (3.64e-2)" "unprognostic (6.31e-2)" "potential prognostic favorable (4.27e-4)" "unprognostic (5.58e-2)" "unprognostic (5.32e-1)" "unprognostic (7.28e-2)" "unprognostic (2.70e-2)" "unprognostic (5.76e-3)" "unprognostic (9.89e-3)" "unprognostic (9.51e-2)" "unprognostic (7.44e-3)" "unprognostic (7.32e-2)" "unprognostic (1.36e-2)" "unprognostic (8.62e-3)" "unprognostic (1.06e-1)" "unprognostic (2.75e-3)" "unprognostic (5.17e-2)" "unprognostic (2.00e-1)" "unprognostic (1.33e-1)" "unprognostic (5.41e-2)" "unprognostic (1.43e-1)" "unprognostic (4.90e-1)" "unprognostic (1.76e-1)" "unprognostic (3.07e-1)" "unprognostic (2.37e-1)" "unprognostic (4.00e-2)" PHLDA1 "DT1P1B11, PHRIP, TDAG51" ENSG00000139289 "Pleckstrin homology like domain family A member 1" Q8WV24 12 76025447-76031776 "Cancer-related genes, Predicted intracellular proteins" Apoptosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 149.9" "Cell type enriched" "Detected in many" 9 "Esophageal apical cells: 3779.3" "Cell type enhanced" "Detected in all" "oligodendrocyte precursor cell: 235.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 6 "monocytes: 1.1;T-cells: 1.6" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016160, HPA019000, HPA063520" Enhanced Supported "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 72: Neuronal - Signal transduction" "Cluster 84: Apical squamous epithelium - Cornification" 16 "Nucleoli, Nucleoli rim" Nucleoplasm "CAB016160: , HPA019000: , HPA063520: " "unprognostic (1.49e-1)" "unprognostic (1.02e-1)" "unprognostic (2.34e-1)" "unprognostic (1.37e-3)" "unprognostic (1.02e-1)" "unprognostic (4.86e-2)" "unprognostic (2.56e-1)" "unprognostic (7.60e-2)" "unprognostic (1.16e-2)" "unprognostic (5.62e-2)" "potential prognostic favorable (6.35e-4)" "unprognostic (4.98e-2)" "unprognostic (7.45e-2)" "unprognostic (2.75e-1)" "unprognostic (1.19e-1)" "unprognostic (5.83e-2)" "potential prognostic unfavorable (1.46e-4)" "unprognostic (4.21e-1)" "unprognostic (4.30e-2)" "unprognostic (6.27e-2)" "unprognostic (6.99e-2)" "unprognostic (8.48e-3)" "unprognostic (2.13e-2)" "unprognostic (8.44e-2)" "unprognostic (2.93e-1)" "unprognostic (5.74e-2)" "unprognostic (2.64e-1)" "unprognostic (1.87e-2)" "unprognostic (2.61e-1)" "unprognostic (8.45e-2)" "unprognostic (1.19e-2)" PHLDA2 "BWR1C, HLDA2, IPL, TSSC3" ENSG00000181649 "Pleckstrin homology like domain family A member 2" Q53GA4 11 2928273-2929420 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 43.5;placenta: 74.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 3200.8;Esophageal apical cells: 580.7;Extravillous trophoblasts: 1636.2;Migrating cytotrophoblasts: 1276.8;Ocular epithelial cells: 891.5;Syncytiotrophoblasts: 6857.9;Urothelial cells: 566.1" "Cell type enriched" "Detected in many" 8 "vascular associated smooth muscle cell: 96.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 17 "dendritic cells: 1.9;monocytes: 1.2;T-cells: 1.8" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Prostate glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA003994 Uncertain Nucleoli NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 69: Skin cancer - ECM organization" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 3 Nucleoli "HPA003994: " "unprognostic (2.76e-1)" "unprognostic (3.30e-2)" "unprognostic (9.80e-2)" "unprognostic (9.23e-2)" "unprognostic (1.51e-2)" "unprognostic (2.42e-1)" "unprognostic (3.83e-2)" "unprognostic (8.05e-3)" "unprognostic (2.32e-1)" "unprognostic (8.15e-3)" "unprognostic (6.16e-3)" "unprognostic (6.86e-2)" "potential prognostic unfavorable (6.98e-5)" "unprognostic (2.19e-2)" "unprognostic (2.59e-3)" "unprognostic (4.85e-3)" "potential prognostic unfavorable (5.05e-4)" "unprognostic (3.04e-3)" "unprognostic (2.31e-2)" "unprognostic (4.94e-1)" "unprognostic (1.30e-2)" "unprognostic (2.04e-2)" "unprognostic (1.44e-1)" "unprognostic (4.21e-2)" "unprognostic (3.19e-2)" "unprognostic (2.83e-2)" "unprognostic (3.70e-1)" "unprognostic (8.93e-2)" "unprognostic (1.09e-1)" "unprognostic (1.54e-1)" PHLDA3 TIH1 ENSG00000174307 "Pleckstrin homology like domain family A member 3" Q9Y5J5 1 201464278-201469237 "Predicted intracellular proteins" Apoptosis "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Epididymal basal cells: 173.3;Esophageal apical cells: 184.3;Esophageal basal cells: 156.5;Esophageal suprabasal cells: 178.5;Late spermatids: 225.7;Ocular epithelial cells: 166.1;Schwann cells: 160.7;Thymic myoid cells: 110.1;Urothelial cells: 154.0" "Cell type enhanced" "Detected in all" "oligodendrocyte: 66.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Spleen - Fibroblasts_1, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027601 Approved NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 100: Stratified epithelial cells - Barrier functions" "HPA027601: " "unprognostic (6.70e-2)" "potential prognostic unfavorable (3.81e-4)" "unprognostic (4.61e-1)" "unprognostic (4.03e-3)" "unprognostic (2.62e-1)" "unprognostic (4.78e-2)" "unprognostic (6.57e-3)" "unprognostic (6.09e-3)" "unprognostic (1.56e-2)" "unprognostic (5.77e-2)" "unprognostic (1.87e-1)" "unprognostic (4.43e-2)" "unprognostic (1.44e-2)" "unprognostic (7.56e-3)" "potential prognostic favorable (5.97e-7)" "unprognostic (2.87e-1)" "unprognostic (1.55e-1)" "unprognostic (6.34e-3)" "unprognostic (3.12e-2)" "unprognostic (1.67e-1)" "unprognostic (2.26e-2)" "unprognostic (1.11e-1)" "unprognostic (3.07e-1)" "unprognostic (2.64e-2)" "unprognostic (3.01e-2)" "unprognostic (4.79e-2)" "unprognostic (6.74e-2)" "unprognostic (3.76e-2)" "unprognostic (1.78e-1)" "unprognostic (1.22e-1)" "unprognostic (4.88e-3)" PHLDB1 "FLJ00141, KIAA0638, LL5a" ENSG00000019144 "Pleckstrin homology like domain family B member 1" Q86UU1 11 118606440-118658031 "Predicted intracellular proteins" "Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 414.0;Decidual stromal cells: 174.9;Fibro-adipogenic progenitors: 211.1;Leydig cells: 144.1;Oligodendrocyte progenitor cells: 133.5;Oligodendrocytes: 373.0;Pericytes: 140.3" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 340.8;oligodendrocyte: 392.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Fibroblasts, Breast - Adipocytes (Breast), Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037959, HPA038448" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytokinetic bridge,Cytosol" Yes No "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 11: White matter - Signal transduction" "Cluster 15: Kidney cancer - Membrane components" "Cluster 89: Adipocytes - Lipid metabolism" 16 "Vesicles, Cytosol" "Nucleoplasm, Plasma membrane, Cytokinetic bridge" "HPA037959: , HPA038448: " "unprognostic (1.21e-1)" "unprognostic (1.91e-1)" "unprognostic (8.77e-2)" "unprognostic (1.16e-2)" "unprognostic (1.26e-1)" "unprognostic (1.24e-1)" "unprognostic (1.84e-1)" "unprognostic (1.40e-1)" "unprognostic (3.80e-1)" "unprognostic (1.01e-1)" "potential prognostic favorable (3.16e-4)" "unprognostic (1.67e-2)" "unprognostic (2.64e-1)" "unprognostic (1.34e-2)" "unprognostic (3.92e-2)" "unprognostic (1.06e-1)" "unprognostic (8.04e-2)" "unprognostic (2.57e-3)" "unprognostic (5.67e-1)" "unprognostic (2.05e-2)" "unprognostic (2.24e-1)" "unprognostic (1.41e-2)" "unprognostic (5.68e-2)" "unprognostic (8.35e-2)" "unprognostic (8.93e-2)" "unprognostic (1.28e-2)" "unprognostic (1.32e-2)" "unprognostic (3.53e-2)" "unprognostic (2.13e-1)" "unprognostic (2.98e-3)" "unprognostic (1.46e-1)" PHLDB2 "FLJ21791, LL5b, LL5beta" ENSG00000144824 "Pleckstrin homology like domain family B member 2" Q86SQ0 3 111732497-111976517 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 463.8;Alveolar cells type 1: 397.3;Basal keratinocytes: 656.2;Distal convoluted tubule cells: 453.8;Epicardial cells: 1132.5;Ocular epithelial cells: 669.2;Salivary basal cells: 479.7;Salivary ionocytes: 693.4;Vascular smooth muscle cells: 384.9" "Cell type enhanced" "Detected in many" "fibroblast: 328.1;pericyte: 431.3;vascular associated smooth muscle cell: 523.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Prostate - Smooth muscle cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035146, HPA035147" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 103: Non-specific - Basic cellular processes" 29 "Plasma membrane, Cytosol" "HPA035146: , HPA035147: " "unprognostic (9.99e-2)" "unprognostic (1.35e-2)" "unprognostic (5.14e-2)" "unprognostic (7.34e-3)" "unprognostic (4.95e-2)" "unprognostic (2.03e-2)" "unprognostic (2.96e-1)" "unprognostic (9.90e-2)" "unprognostic (3.95e-2)" "unprognostic (1.55e-1)" "potential prognostic favorable (5.25e-10)" "unprognostic (1.53e-1)" "unprognostic (2.89e-1)" "unprognostic (3.11e-1)" "unprognostic (2.21e-2)" "unprognostic (2.28e-2)" "unprognostic (1.27e-1)" "unprognostic (1.13e-1)" "unprognostic (5.77e-1)" "unprognostic (9.49e-3)" "unprognostic (2.77e-3)" "unprognostic (1.33e-1)" "unprognostic (1.72e-3)" "unprognostic (2.80e-1)" "unprognostic (1.36e-1)" "unprognostic (1.02e-1)" "unprognostic (6.05e-2)" "unprognostic (1.82e-3)" "unprognostic (2.21e-1)" "unprognostic (1.09e-1)" "unprognostic (7.07e-2)" PHLDB3 FLJ40193 ENSG00000176531 "Pleckstrin homology like domain family B member 3" Q6NSJ2 19 43474954-43504935 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 43.0;skin 1: 44.4" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 596.2;Esophageal suprabasal cells: 151.2;Ocular epithelial cells: 98.7;Suprabasal keratinocytes: 114.3;Syncytiotrophoblasts: 116.4;Urothelial cells: 99.5" "Cell type enhanced" "Detected in all" "pericyte: 87.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA043425 Approved Approved "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 6 "Nuclear speckles" "Plasma membrane, Cytosol" "HPA043425: " "unprognostic (5.05e-2)" "unprognostic (3.87e-2)" "unprognostic (1.10e-1)" "unprognostic (7.16e-2)" "unprognostic (1.12e-1)" "unprognostic (7.80e-3)" "unprognostic (4.82e-2)" "unprognostic (1.15e-1)" "unprognostic (1.25e-1)" "unprognostic (7.25e-2)" "potential prognostic favorable (4.36e-4)" "unprognostic (3.15e-3)" "unprognostic (4.55e-2)" "unprognostic (3.19e-1)" "unprognostic (8.62e-2)" "unprognostic (4.90e-2)" "unprognostic (9.66e-2)" "unprognostic (1.92e-1)" "unprognostic (3.69e-2)" "unprognostic (9.92e-3)" "unprognostic (2.24e-1)" "potential prognostic favorable (1.60e-4)" "unprognostic (1.67e-2)" "unprognostic (1.67e-2)" "unprognostic (1.45e-1)" "unprognostic (1.32e-1)" "unprognostic (1.81e-1)" "unprognostic (2.36e-2)" "unprognostic (2.48e-1)" "unprognostic (1.41e-1)" "unprognostic (3.97e-1)" PHLPP1 "KIAA0606, PHLPP, PLEKHE1, PPM3A, SCOP" ENSG00000081913 "PH domain and leucine rich repeat protein phosphatase 1" O60346 18 62715541-62980433 "Enzymes, Predicted intracellular proteins" Apoptosis "Hydrolase, Protein phosphatase" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 31.8" "Cell type enhanced" "Detected in many" "Bergmann glia: 894.5;Melanocytes: 965.5;Neutrophils: 891.4;Oligodendrocytes: 2127.7" "Cell type enhanced" "Detected in all" "oligodendrocyte: 2621.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "neutrophil: 4.0;T-reg: 1.3" "Group enriched" "Detected in many" 7 "granulocytes: 4.0;T-cells: 1.3" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Pituitary gland - Undifferentiated cells (Pituitary gland), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020200 Approved NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 6: Leukemia - Signal transduction" "Cluster 80: Oligodendrocytes - Myelination" 28 "HPA020200: " "unprognostic (1.55e-1)" "unprognostic (1.72e-1)" "unprognostic (2.99e-2)" "unprognostic (1.34e-1)" "unprognostic (1.15e-2)" "unprognostic (1.33e-1)" "unprognostic (2.53e-1)" "unprognostic (3.75e-3)" "unprognostic (5.66e-2)" "unprognostic (1.21e-2)" "potential prognostic favorable (2.42e-5)" "unprognostic (2.22e-3)" "unprognostic (6.30e-3)" "unprognostic (1.26e-2)" "unprognostic (2.41e-1)" "unprognostic (9.75e-2)" "unprognostic (1.83e-2)" "unprognostic (9.62e-2)" "potential prognostic favorable (4.91e-4)" "unprognostic (2.56e-1)" "unprognostic (1.80e-1)" "unprognostic (7.06e-2)" "unprognostic (8.89e-2)" "unprognostic (4.75e-2)" "unprognostic (2.28e-1)" "unprognostic (2.17e-1)" "unprognostic (1.56e-1)" "unprognostic (2.85e-1)" "unprognostic (4.31e-2)" "unprognostic (4.33e-1)" "unprognostic (7.85e-2)" PHLPP2 "KIAA0931, PHLPPL, PPM3B" ENSG00000040199 "PH domain and leucine rich repeat protein phosphatase 2" Q6ZVD8 16 71637835-71724701 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 20.7;retina: 29.8" "Cell type enhanced" "Detected in many" "Colonocytes: 153.1;Cone photoreceptor cells: 322.9;Enterocytes: 285.5;Retinal pigment epithelial cells: 200.4;Rod photoreceptor cells: 346.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040761, HPA041837, HPA048598" Approved Supported "Vesicles,Cytokinetic bridge,Mitotic spindle,Primary cilium,Primary cilium tip,Centriolar satellite,Basal body,Cytosol" Yes No "Cluster 42: Retina - Visual perception" "Cluster 1: Neurons - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 79: Photoreceptor cells - Phototransduction" 12 "Cytokinetic bridge, Mitotic spindle, Primary cilium, Cytosol" "Vesicles, Primary cilium tip, Centriolar satellite, Basal body" "HPA040761: , HPA041837: , HPA048598: " "unprognostic (3.71e-2)" "unprognostic (8.38e-2)" "unprognostic (1.55e-1)" "unprognostic (2.36e-1)" "unprognostic (6.38e-2)" "unprognostic (1.70e-1)" "unprognostic (4.61e-1)" "unprognostic (1.47e-2)" "unprognostic (2.27e-1)" "unprognostic (2.48e-2)" "unprognostic (1.51e-2)" "unprognostic (2.49e-1)" "unprognostic (9.87e-2)" "unprognostic (5.21e-2)" "unprognostic (1.05e-1)" "unprognostic (9.80e-2)" "unprognostic (6.40e-3)" "unprognostic (7.96e-2)" "unprognostic (6.89e-2)" "unprognostic (6.54e-2)" "unprognostic (7.34e-2)" "unprognostic (6.03e-3)" "unprognostic (1.24e-1)" "unprognostic (2.30e-2)" "unprognostic (2.47e-2)" "unprognostic (1.74e-1)" "unprognostic (1.78e-1)" "unprognostic (3.31e-2)" "unprognostic (9.46e-2)" "unprognostic (3.20e-3)" "unprognostic (1.97e-2)" PHOSPHO1 ENSG00000173868 "Phosphoethanolamine/phosphocholine phosphatase 1" Q8TCT1 17 49223366-49230787 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Mineral balance" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 90.6" "Cell type enriched" "Detected in some" 8 "Late spermatids: 2845.4" "Cell type enhanced" "Detected in some" "lower rhombic lip: 3.2;mammillary body: 3.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 160 "eosinophil: 171.7;neutrophil: 428.7" "Lineage enriched" "Detected in many" 228 "granulocytes: 428.7" "Cancer enriched" "Detected in many" 8 "Bone cancer: 39.9" "Adipose visceral - Neutrophils, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA065025 Approved "Plasma membrane,Actin filaments" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 47: Testis - Mixed function" "Cluster 45: Non-specific - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 1 "Actin filaments" "Plasma membrane" "HPA065025: " "unprognostic (7.60e-3)" "unprognostic (7.38e-2)" "unprognostic (1.04e-1)" "unprognostic (1.79e-1)" "unprognostic (5.19e-2)" "unprognostic (1.35e-1)" "unprognostic (1.35e-1)" "unprognostic (1.36e-1)" "unprognostic (1.01e-1)" "unprognostic (6.76e-2)" "unprognostic (2.37e-2)" "unprognostic (2.23e-1)" "unprognostic (1.18e-1)" "unprognostic (1.57e-1)" PHOSPHO2 MGC22679 ENSG00000144362 "Phosphatase, orphan 2" Q8TCD6 2 169694454-169701708 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Early spermatids: 51.4;Late primary spermatocytes: 37.2;Late spermatids: 9.5;Tuft cells: 11.5" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Prostate - Prostate glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034726, HPA034727" Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 7 Vesicles Nucleoplasm "HPA034726: , HPA034727: " "unprognostic (1.70e-2)" "unprognostic (6.43e-2)" "unprognostic (1.91e-1)" "unprognostic (1.46e-3)" "unprognostic (1.67e-2)" "unprognostic (9.01e-2)" "unprognostic (1.27e-1)" "unprognostic (1.61e-1)" "unprognostic (1.37e-1)" "unprognostic (3.05e-2)" "potential prognostic favorable (2.61e-8)" "unprognostic (7.94e-3)" "unprognostic (2.29e-2)" "potential prognostic unfavorable (9.29e-6)" "unprognostic (5.78e-2)" "unprognostic (2.53e-1)" "unprognostic (1.45e-2)" "unprognostic (1.50e-1)" "unprognostic (4.39e-2)" "unprognostic (2.51e-1)" "unprognostic (1.22e-2)" "unprognostic (2.23e-1)" "unprognostic (8.45e-3)" "unprognostic (3.33e-1)" "potential prognostic favorable (3.54e-4)" "unprognostic (6.42e-2)" "unprognostic (7.62e-2)" "unprognostic (5.08e-1)" "unprognostic (1.62e-1)" "unprognostic (2.07e-2)" "unprognostic (1.81e-1)" PHOX2A "ARIX, CFEOM2, FEOM2, PMX2A" ENSG00000165462 "Paired like homeobox 2A" O14813 11 72239077-72245664 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "adrenal gland: 18.8" "Cell type enriched" "Detected in some" 6 "Adrenal medulla cells: 63.8" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Ovary Serous Cystadenocarcinoma (TCGA): 13.6" "Region enriched" "Detected in some" 9 "pons: 38.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 755 "Neuroblastoma: 337.6" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" "HPA053810, HPA065621, HPA078004" Enhanced Supported Nucleoplasm No NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 18: Adrenal cortex cells - Steroidogensis" 3 Nucleoplasm "HPA053810: , HPA065621: , HPA078004: " "unprognostic (1.21e-1)" "unprognostic (1.46e-2)" "unprognostic (1.87e-1)" PHOX2B "NBPhox, PMX2B" ENSG00000109132 "Paired like homeobox 2B" Q99453 4 41744082-41748725 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 12 "adrenal gland: 8.1;intestine: 2.4" "Cell type enriched" "Detected in some" 72 "Adrenal medulla cells: 95.7" "Cell type enriched" "Detected in single" 8 "splatter: 1.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 41 "medulla oblongata: 21.8;pons: 32.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 93 "Neuroblastoma: 170.8" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells" "Region enriched" "Detected in single" 17 "pons and medulla: 5.6" "Group enriched" "Detected in some" 27 "medulla oblongata: 2.2;pons: 3.1" "HPA074325, HPA074941" Enhanced Enhanced Nucleoplasm NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 43: Hindbrain - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 18: Adrenal cortex cells - Steroidogensis" 1 Nucleoplasm "HPA074325: , HPA074941: " PHPT1 "bA216L13.10, CGI-202, DKFZp564M173, HSPC141, PHP14" ENSG00000054148 "Phosphohistidine phosphatase 1" Q9NRX4 9 136848724-136851027 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 652.0;Extravillous trophoblasts: 626.3;Late spermatids: 1540.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "CAB013584, HPA020952" Approved Approved "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA 950000 "Cluster 13: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cellular respiration" "Cluster 27: Non-specific - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 97: Non-specific - Cellular respiration" 2 Cytosol "Nucleoplasm, Nuclear bodies, Plasma membrane" "CAB013584: , HPA020952: " "unprognostic (9.09e-2)" "unprognostic (1.79e-2)" "unprognostic (2.39e-1)" "unprognostic (2.66e-1)" "unprognostic (1.68e-2)" "unprognostic (8.61e-2)" "unprognostic (2.05e-1)" "unprognostic (1.02e-1)" "unprognostic (1.32e-1)" "unprognostic (1.12e-1)" "potential prognostic favorable (1.12e-5)" "unprognostic (1.37e-3)" "unprognostic (1.29e-3)" "unprognostic (3.93e-3)" "unprognostic (4.58e-2)" "unprognostic (1.09e-2)" "unprognostic (3.53e-2)" "unprognostic (1.26e-3)" "unprognostic (4.61e-1)" "unprognostic (2.50e-1)" "unprognostic (9.09e-2)" "unprognostic (6.15e-3)" "unprognostic (3.69e-2)" "unprognostic (3.00e-2)" "unprognostic (3.14e-2)" "unprognostic (5.51e-3)" "unprognostic (1.01e-1)" "unprognostic (2.18e-2)" "unprognostic (2.27e-1)" "unprognostic (9.34e-2)" "unprognostic (4.27e-2)" PHRF1 "KIAA1542, PPP1R125, RNF221" ENSG00000070047 "PHD and ring finger domains 1" Q9P1Y6 11 576470-612222 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 24.9;Loop of henle epithelial cells: 23.2;Podocytes: 26.6;Proximal tubule cells: 32.1;Renal collecting duct intercalated cells: 27.7;Renal connecting tubule cells: 27.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019867, HPA062933" Uncertain NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 24: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 40: Non-specific - Unknown function" "Cluster 102: Non-specific - Mixed function" 9 "HPA019867: , HPA062933: " "unprognostic (9.67e-3)" "unprognostic (4.70e-2)" "unprognostic (2.41e-1)" "unprognostic (1.59e-2)" "unprognostic (4.92e-2)" "unprognostic (1.82e-3)" "unprognostic (3.17e-1)" "unprognostic (2.84e-1)" "unprognostic (1.95e-1)" "unprognostic (1.89e-2)" "unprognostic (2.94e-3)" "unprognostic (1.76e-1)" "unprognostic (1.72e-1)" "unprognostic (2.20e-3)" "unprognostic (5.87e-2)" "unprognostic (1.61e-3)" "unprognostic (7.10e-2)" "unprognostic (1.66e-1)" "unprognostic (5.16e-2)" "unprognostic (4.80e-1)" "potential prognostic unfavorable (2.09e-4)" "unprognostic (1.76e-1)" "unprognostic (2.37e-1)" "unprognostic (1.64e-2)" "unprognostic (3.49e-1)" "unprognostic (1.44e-1)" "unprognostic (8.33e-2)" "unprognostic (1.21e-1)" "unprognostic (3.31e-1)" PHTF1 PHTF ENSG00000116793 "Putative homeodomain transcription factor 1" Q9UMS5 1 113696831-113759489 "Plasma proteins, Predicted membrane proteins, Transcription factors" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 257.4;Megakaryocyte-Erythroid progenitors: 661.9;Neutrophils: 485.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pituitary gland - Lactotropes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059486 Approved "Nucleoli,Nuclear bodies" No No "Cluster 45: Eosinophils - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 1 "Nuclear bodies" Nucleoli "HPA059486: " "unprognostic (2.84e-1)" "unprognostic (2.28e-1)" "unprognostic (2.37e-1)" "unprognostic (4.58e-1)" "unprognostic (3.32e-2)" "unprognostic (1.90e-1)" "unprognostic (2.41e-1)" "unprognostic (3.62e-1)" "unprognostic (1.26e-1)" "unprognostic (1.77e-2)" "unprognostic (8.70e-3)" "unprognostic (1.77e-1)" "unprognostic (1.66e-1)" "unprognostic (5.10e-2)" "unprognostic (2.74e-2)" "unprognostic (5.22e-2)" "unprognostic (6.66e-2)" "unprognostic (6.01e-2)" "unprognostic (1.73e-1)" "unprognostic (5.68e-3)" "unprognostic (6.98e-2)" "unprognostic (2.32e-1)" "unprognostic (6.10e-2)" "unprognostic (3.72e-1)" "unprognostic (2.12e-1)" "unprognostic (2.99e-1)" "unprognostic (1.72e-2)" "unprognostic (1.80e-1)" "unprognostic (3.24e-1)" "unprognostic (1.03e-1)" "unprognostic (4.27e-2)" PHTF2 DKFZp434D166 ENSG00000006576 "Putative homeodomain transcription factor 2" Q8N3S3 7 77798773-77957503 "Predicted membrane proteins, Transcription factors" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 104.0;tongue: 50.7" "Cell type enhanced" "Detected in many" "Mast cells: 274.1;Myonuclei: 629.3;Platelets: 289.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 44.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 25.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012312 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 53: Neurons - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" Nucleoplasm Cytosol "HPA012312: " "unprognostic (1.55e-1)" "unprognostic (2.78e-1)" "unprognostic (3.48e-2)" "unprognostic (1.70e-1)" "unprognostic (5.90e-2)" "unprognostic (2.69e-2)" "unprognostic (8.01e-2)" "unprognostic (2.14e-1)" "unprognostic (8.47e-2)" "potential prognostic unfavorable (8.99e-4)" "unprognostic (4.43e-2)" "unprognostic (8.00e-2)" "potential prognostic unfavorable (7.52e-4)" "unprognostic (6.03e-3)" "unprognostic (2.09e-2)" "unprognostic (9.62e-2)" "unprognostic (1.87e-3)" "unprognostic (1.15e-1)" "unprognostic (2.64e-1)" "unprognostic (4.84e-2)" "potential prognostic unfavorable (2.11e-5)" "unprognostic (1.49e-2)" "unprognostic (7.65e-3)" "unprognostic (5.20e-2)" "unprognostic (2.33e-1)" "unprognostic (5.76e-3)" "unprognostic (5.53e-2)" "unprognostic (2.28e-2)" "unprognostic (2.46e-1)" "potential prognostic unfavorable (5.71e-4)" "unprognostic (6.04e-2)" PHYH "PAHX, PHYH1, RD" ENSG00000107537 "Phytanoyl-CoA 2-hydroxylase" O14832 10 13277796-13302412 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Cataract, Deafness, Disease variant, Ichthyosis, Peroxisome biogenesis disorder, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 624.2;skeletal muscle: 453.0;tongue: 385.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 189.9;Enterocytes: 137.2;Hepatocytes: 172.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 223.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Smooth muscle cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007598, HPA011796" Enhanced NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 19 "HPA007598: , HPA011796: " "unprognostic (8.03e-3)" "potential prognostic unfavorable (1.00e-4)" "unprognostic (3.55e-1)" "unprognostic (2.24e-1)" "unprognostic (5.97e-2)" "unprognostic (9.59e-2)" "unprognostic (1.37e-1)" "unprognostic (3.82e-3)" "unprognostic (4.86e-3)" "unprognostic (2.23e-3)" "potential prognostic favorable (4.66e-9)" "unprognostic (1.45e-1)" "unprognostic (3.59e-2)" "unprognostic (1.50e-1)" "unprognostic (3.83e-2)" "unprognostic (4.65e-1)" "unprognostic (7.78e-3)" "unprognostic (3.26e-1)" "unprognostic (4.68e-2)" "unprognostic (3.49e-1)" "unprognostic (4.47e-2)" "unprognostic (4.08e-2)" "unprognostic (2.54e-1)" "unprognostic (1.31e-1)" "potential prognostic favorable (3.44e-4)" "unprognostic (5.25e-2)" "unprognostic (2.34e-1)" "unprognostic (2.35e-1)" "unprognostic (7.03e-2)" "unprognostic (2.18e-2)" "unprognostic (6.40e-2)" PHYHD1 MGC16638 ENSG00000175287 "Phytanoyl-CoA dioxygenase domain containing 1" Q5SRE7 9 128920966-128942041 "Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 56.9;Bergmann glia: 74.9;Cone photoreceptor cells: 72.5;Leydig cells: 53.3;Rod photoreceptor cells: 104.3" "Cell type enhanced" "Detected in many" "astrocyte: 88.8;Bergmann glia: 83.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "plasmacytoid DC: 13.0" "Lineage enriched" "Detected in many" 4 "dendritic cells: 13.0" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012115 Approved "Nuclear speckles" NA NA 15000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 44: Non-specific - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" 3 "Nuclear speckles" "HPA012115: " "unprognostic (1.40e-3)" "unprognostic (1.63e-2)" "unprognostic (1.32e-1)" "unprognostic (4.19e-1)" "unprognostic (1.99e-1)" "unprognostic (7.92e-2)" "unprognostic (1.80e-1)" "unprognostic (6.73e-2)" "unprognostic (1.66e-2)" "unprognostic (2.66e-1)" "unprognostic (1.20e-1)" "unprognostic (1.14e-2)" "potential prognostic favorable (4.27e-9)" "unprognostic (2.49e-2)" "unprognostic (3.93e-3)" "unprognostic (3.79e-2)" "unprognostic (1.06e-1)" "unprognostic (9.30e-2)" "unprognostic (4.62e-2)" "unprognostic (2.21e-1)" "unprognostic (1.51e-1)" "unprognostic (1.22e-2)" "unprognostic (3.85e-1)" "unprognostic (9.37e-3)" "unprognostic (4.78e-2)" "unprognostic (9.25e-3)" "unprognostic (1.24e-1)" "unprognostic (1.05e-2)" "unprognostic (8.39e-2)" "unprognostic (8.46e-2)" "potential prognostic favorable (7.75e-4)" PHYHIP "DYRK1AP3, KIAA0273, PAHX-AP" ENSG00000168490 "Phytanoyl-CoA 2-hydroxylase interacting protein" Q92561 8 22219703-22232101 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 347.1" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 88.7;Brain inhibitory neurons: 62.8;Corticotrophs: 44.2;Other brain neurons: 30.8;Pituicytes/FSCs: 22.0;Podocytes: 111.8;Smooth muscle cells: 38.7" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 14.1;Thyroid Carcinoma (TCGA): 12.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Kidney - Podocytes, Lung - Fibroblasts_2, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "amygdala: 133.6;basal ganglia: 395.5;cerebellum: 336.2;cerebral cortex: 333.8;hippocampal formation: 387.6" "HPA068030, HPA069318" Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 10 Mitochondria Nucleoplasm "HPA068030: , HPA069318: " "unprognostic (7.78e-3)" "potential prognostic favorable (3.77e-4)" "unprognostic (1.67e-2)" "unprognostic (5.41e-2)" "unprognostic (1.37e-3)" "unprognostic (3.06e-2)" "unprognostic (7.64e-2)" "unprognostic (7.02e-3)" "unprognostic (1.51e-1)" "unprognostic (1.86e-1)" "unprognostic (3.26e-1)" "unprognostic (7.70e-2)" "potential prognostic favorable (5.18e-4)" "unprognostic (2.65e-2)" "potential prognostic unfavorable (3.68e-5)" "unprognostic (8.87e-2)" "unprognostic (2.43e-2)" "unprognostic (1.80e-1)" PHYHIPL "Em:AC025038.1, KIAA1796" ENSG00000165443 "Phytanoyl-CoA 2-hydroxylase interacting protein like" Q96FC7 10 59176643-59247774 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 17.4;brain: 51.4;retina: 28.2" "Cell type enhanced" "Detected in many" "Astrocytes: 377.2;Bergmann glia: 804.8;Ependymal cells: 318.6;Late primary spermatocytes: 301.5;Late spermatids: 420.6;Müller glia: 404.8;Oligodendrocyte progenitor cells: 498.2;Oligodendrocytes: 538.2;Pituicytes/FSCs: 354.3;Retinal bipolar cells: 308.8;Retinal ganglion cells: 332.2;Retinal horizontal cells: 306.5;Retinal pigment epithelial cells: 311.2" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 1081.9" "Group enriched" "Detected in many" 4 "Glioblastoma Multiforme (TCGA): 19.5;Kidney Renal Clear Cell Carcinoma (TCGA): 7.5;Kidney Renal Papillary Cell Carcinoma (TCGA): 19.3;Prostate Adenocarcinoma (TCGA): 9.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Neuroblastoma: 21.1" "Minor Salivary Gland - Smooth muscle cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038746 Uncertain Approved Cytosol NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 27: Non-specific - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 1 Cytosol "HPA038746: " "unprognostic (2.28e-1)" "unprognostic (2.45e-2)" "unprognostic (1.13e-3)" "unprognostic (3.18e-2)" "potential prognostic favorable (1.42e-8)" "unprognostic (1.03e-3)" "potential prognostic favorable (1.78e-5)" "unprognostic (1.27e-1)" "unprognostic (1.17e-2)" "unprognostic (1.23e-1)" "unprognostic (7.35e-2)" "potential prognostic favorable (1.54e-4)" "unprognostic (1.01e-1)" "unprognostic (3.19e-1)" "unprognostic (2.39e-2)" "unprognostic (1.18e-1)" "potential prognostic unfavorable (5.75e-4)" "unprognostic (1.12e-1)" PHYKPL "AGXT2L2, MGC15875" ENSG00000175309 "5-phosphohydroxy-L-lysine phospho-lyase" Q8IUZ5 5 178208471-178232802 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Lyase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036461, HPA063608" Approved Approved Mitochondria Yes No 120000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 6: Non-specific - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 8 Mitochondria "HPA036461: , HPA063608: " "unprognostic (8.70e-2)" "unprognostic (2.18e-1)" "unprognostic (4.30e-2)" "unprognostic (3.65e-2)" "unprognostic (5.47e-2)" "unprognostic (1.06e-1)" "unprognostic (4.14e-1)" "unprognostic (4.30e-2)" "unprognostic (4.68e-2)" "potential prognostic favorable (6.18e-5)" "unprognostic (1.56e-2)" "unprognostic (1.28e-2)" "unprognostic (2.52e-2)" "unprognostic (4.66e-2)" "unprognostic (5.73e-2)" "unprognostic (1.50e-2)" "unprognostic (2.60e-1)" "unprognostic (2.60e-2)" "unprognostic (7.70e-2)" "unprognostic (1.13e-1)" "unprognostic (4.10e-3)" "unprognostic (4.35e-1)" "unprognostic (2.06e-3)" "unprognostic (1.15e-1)" "unprognostic (2.13e-3)" "unprognostic (2.06e-1)" "unprognostic (3.83e-3)" "unprognostic (2.16e-1)" "unprognostic (1.48e-1)" PI15 P25TI ENSG00000137558 "Peptidase inhibitor 15" O43692 8 74824534-74855029 "Predicted secreted proteins" "Developmental protein, Protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 51.3;prostate: 29.1;smooth muscle: 46.6" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 187.0;Breast hormone-responsive cells: 157.8;Pericytes: 33.2;Prostatic club cells: 56.8;Prostatic glandular cells: 105.1;Salivary myoepithelial cells: 27.5;Smooth muscle cells: 84.5;Vascular smooth muscle cells: 32.4" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 7 "Breast Invasive Carcinoma (TCGA): 19.2;Prostate Adenocarcinoma (TCGA): 28.6;Skin Cutaneous Melanoma (TCGA): 14.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Rhabdoid: 99.9;Sarcoma: 118.3" "Adipose subcutaneous - Smooth muscle cells, Breast - Breast glandular cells" "Not detected" "Not detected" "Region enriched" "Detected in single" 9 "spinal cord: 8.3" "HPA006593, HPA030057" Uncertain Approved Vesicles,Cytosol "Secreted in other tissues" "Developmental protein" NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 53: Neurons - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 53 Vesicles Cytosol "HPA006593: , HPA030057: " "unprognostic (1.10e-1)" "unprognostic (1.27e-1)" "unprognostic (4.54e-2)" "unprognostic (2.93e-1)" "unprognostic (1.40e-1)" "unprognostic (8.44e-2)" "unprognostic (2.44e-1)" "unprognostic (1.02e-1)" "unprognostic (3.99e-3)" "unprognostic (2.18e-2)" "unprognostic (4.08e-2)" "unprognostic (2.59e-2)" "unprognostic (2.46e-2)" "potential prognostic unfavorable (4.97e-4)" "unprognostic (2.25e-2)" "unprognostic (6.72e-2)" "unprognostic (1.84e-1)" "unprognostic (1.30e-3)" "unprognostic (1.73e-1)" "unprognostic (9.03e-2)" PI16 "CD364, dJ90K10.5, MGC45378, MSMBBP" ENSG00000164530 "Peptidase inhibitor 16" Q6UXB8 6 36948263-36964837 "CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 131.9;heart muscle: 140.6;vagina: 143.1" "Group enriched" "Detected in some" 4 "Fibro-adipogenic progenitors: 130.2;Fibroblasts: 226.1;Hepatic stellate cells: 161.4;Leydig cells: 335.5;Peritubular myoid cells: 198.5" "Cell type enhanced" "Detected in many" "ependymal cell: 28.7;fibroblast: 33.8;oligodendrocyte: 82.0" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 23.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 66.3" "Lineage enriched" "Detected in many" 5 "T-cells: 66.3" "Cancer enriched" "Detected in some" 12 "Kidney cancer: 17.7" "Adipose subcutaneous - Adipose progenitor cells, Colon - Fibroblasts, Minor Salivary Gland - Fibroblasts, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skin - Fibroblasts_1, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 6 "spinal cord: 45.1" HPA076574 Approved "Secreted to blood" "Enzyme inhibitor" NA NA 900000000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 35: Non-specific - Mixed function" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 6 "HPA076574: " "unprognostic (6.63e-2)" "unprognostic (6.11e-2)" "potential prognostic favorable (3.77e-4)" "unprognostic (7.74e-3)" "unprognostic (4.72e-2)" "unprognostic (1.26e-1)" "unprognostic (1.80e-1)" "unprognostic (2.02e-1)" "unprognostic (1.86e-1)" "unprognostic (2.28e-1)" "unprognostic (1.45e-2)" "unprognostic (8.02e-2)" "unprognostic (2.72e-2)" "unprognostic (8.33e-2)" "unprognostic (1.79e-2)" "unprognostic (5.16e-2)" "unprognostic (6.05e-2)" "unprognostic (1.70e-1)" "unprognostic (3.61e-2)" "unprognostic (1.17e-1)" "unprognostic (9.99e-2)" PI3 "cementoin, ELAFIN, ESI, SKALP, WAP3, WFDC14" ENSG00000124102 "Peptidase inhibitor 3" P19957 20 45174902-45176544 "Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 1450.9;esophagus: 2187.8;lymphoid tissue: 1967.8;vagina: 1668.8" "Cell type enriched" "Detected in many" 5 "Esophageal apical cells: 14978.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 5253.2" "Group enriched" "Detected in some" 12 "cerebral cortex: 24.5;pons: 14.5;thalamus: 39.8" "Immune cell enriched" "Detected in some" 1026 "neutrophil: 1774.5" "Lineage enriched" "Detected in single" 4390 "granulocytes: 1774.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 544.0;prostate cancer: 235.4" "Colon - Colon enterocytes" "CAB009449, HPA017737" Enhanced Approved "Plasma membrane" "Secreted to blood" "Enzyme inhibitor" NA NA 3100000 "Cluster 4: Neutrophils - Degranulation" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 2 "Plasma membrane" "CAB009449: , HPA017737: " "unprognostic (3.37e-1)" "unprognostic (1.80e-3)" "unprognostic (2.59e-1)" "unprognostic (3.96e-2)" "unprognostic (2.16e-1)" "unprognostic (2.57e-2)" "unprognostic (4.25e-2)" "unprognostic (1.28e-2)" "unprognostic (2.40e-1)" "potential prognostic unfavorable (9.52e-10)" "unprognostic (1.48e-3)" "unprognostic (3.43e-2)" "unprognostic (1.32e-3)" "unprognostic (4.98e-2)" "unprognostic (3.26e-3)" "unprognostic (9.85e-2)" "unprognostic (4.62e-2)" "unprognostic (3.48e-1)" "potential prognostic unfavorable (1.89e-5)" "unprognostic (5.13e-2)" "unprognostic (1.02e-3)" "unprognostic (2.24e-1)" "unprognostic (9.08e-3)" "unprognostic (3.06e-2)" "unprognostic (2.44e-1)" "unprognostic (6.03e-2)" "unprognostic (1.45e-1)" "unprognostic (1.09e-1)" "unprognostic (5.39e-2)" PI4K2A "DKFZP761G1923, PI4KII, PIK42A" ENSG00000155252 "Phosphatidylinositol 4-kinase type 2 alpha" Q9BTU6 10 97640671-97676434 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Kinase, Transferase" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 101.6;Hofbauer cells: 57.1;Ocular epithelial cells: 32.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB030649, HPA076857" Approved Approved "Plasma membrane" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 10 "Plasma membrane" "CAB030649: , HPA076857: " "unprognostic (8.27e-2)" "unprognostic (1.16e-2)" "unprognostic (4.35e-2)" "unprognostic (3.48e-2)" "unprognostic (8.06e-3)" "unprognostic (2.06e-2)" "unprognostic (1.84e-1)" "unprognostic (6.91e-3)" "unprognostic (2.81e-3)" "unprognostic (7.98e-2)" "unprognostic (8.29e-3)" "unprognostic (1.22e-2)" "unprognostic (1.02e-2)" "unprognostic (2.07e-2)" "unprognostic (2.34e-1)" "unprognostic (3.34e-1)" "unprognostic (1.42e-2)" "unprognostic (6.01e-3)" "unprognostic (2.92e-3)" "unprognostic (3.47e-3)" "unprognostic (4.49e-2)" "unprognostic (5.36e-2)" "unprognostic (9.41e-2)" "unprognostic (2.10e-1)" "unprognostic (1.87e-1)" "unprognostic (2.90e-3)" "unprognostic (1.32e-1)" "unprognostic (1.89e-1)" "unprognostic (2.86e-1)" "unprognostic (4.43e-1)" "unprognostic (2.67e-1)" PI4K2B "FLJ11105, PI4KIIB, PIK42B" ENSG00000038210 "Phosphatidylinositol 4-kinase type 2 beta" Q8TCG2 4 25160663-25279204 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 54.1" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004099 Enhanced Supported Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 77: Intestine - Digestion" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 16 Cytosol "HPA004099: " "unprognostic (1.10e-1)" "unprognostic (1.79e-2)" "unprognostic (1.45e-2)" "unprognostic (3.74e-2)" "potential prognostic favorable (1.18e-4)" "unprognostic (1.10e-1)" "unprognostic (4.01e-1)" "unprognostic (2.46e-2)" "unprognostic (1.68e-2)" "potential prognostic unfavorable (2.26e-5)" "potential prognostic favorable (3.95e-6)" "unprognostic (7.84e-2)" "unprognostic (5.83e-2)" "unprognostic (3.32e-2)" "unprognostic (3.11e-2)" "unprognostic (1.80e-1)" "unprognostic (8.22e-2)" "unprognostic (1.36e-2)" "unprognostic (2.01e-2)" "unprognostic (3.70e-2)" "unprognostic (2.44e-1)" "unprognostic (9.47e-3)" "unprognostic (2.38e-1)" "unprognostic (8.06e-2)" "unprognostic (2.44e-3)" "unprognostic (1.26e-1)" "unprognostic (1.03e-1)" "unprognostic (2.33e-2)" "unprognostic (2.28e-1)" "potential prognostic unfavorable (2.07e-4)" "unprognostic (3.15e-1)" PI4KA "PI4K-ALPHA, pi4K230, PIK4CA" ENSG00000241973 "Phosphatidylinositol 4-kinase alpha" P42356 22 20707691-20859417 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Kinase, Transferase" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 103.1" "Cell type enhanced" "Detected in all" "pDCs: 404.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009092, HPA075515" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 38 Nucleoplasm "Plasma membrane" "CAB009092: , HPA075515: " "unprognostic (1.98e-2)" "unprognostic (7.09e-2)" "unprognostic (1.34e-1)" "unprognostic (2.01e-3)" "unprognostic (1.36e-2)" "unprognostic (1.92e-1)" "unprognostic (6.34e-2)" "unprognostic (1.88e-1)" "unprognostic (7.69e-2)" "unprognostic (6.54e-3)" "validated prognostic favorable (1.25e-6)" "validated prognostic favorable (3.63e-4)" "unprognostic (7.40e-3)" "unprognostic (6.76e-3)" "unprognostic (6.27e-3)" "unprognostic (2.55e-1)" "unprognostic (2.04e-1)" "unprognostic (3.91e-3)" "unprognostic (4.79e-2)" "unprognostic (2.08e-2)" "unprognostic (2.02e-1)" "unprognostic (8.40e-3)" "unprognostic (3.26e-2)" "unprognostic (2.30e-1)" "unprognostic (1.95e-2)" "unprognostic (1.60e-2)" "unprognostic (9.12e-2)" "unprognostic (1.41e-1)" "unprognostic (2.45e-1)" "unprognostic (9.13e-2)" "unprognostic (2.81e-1)" PI4KB "PI4K-BETA, pi4K92, PIK4CB" ENSG00000143393 "Phosphatidylinositol 4-kinase beta" Q9UBF8 1 151291797-151327715 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Host-virus interaction, Lipid metabolism" "Kinase, Transferase" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006280, HPA006281, CAB022071" Approved Supported "Golgi apparatus" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 24: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 45: Non-specific - Nuclear processes" "Cluster 69: Urothelial cells - Basic cellular functions" 27 "Golgi apparatus" "CAB022071: , HPA006280: , HPA006281: " "unprognostic (3.30e-2)" "unprognostic (1.43e-1)" "unprognostic (8.16e-3)" "unprognostic (3.56e-2)" "unprognostic (1.50e-2)" "unprognostic (2.59e-1)" "unprognostic (1.07e-1)" "unprognostic (2.17e-2)" "unprognostic (4.64e-2)" "unprognostic (3.74e-2)" "unprognostic (8.25e-2)" "unprognostic (2.00e-1)" "unprognostic (1.96e-1)" "unprognostic (2.41e-3)" "unprognostic (3.54e-1)" "unprognostic (4.25e-2)" "unprognostic (4.01e-2)" "unprognostic (1.93e-1)" "unprognostic (2.18e-1)" "unprognostic (1.49e-1)" "unprognostic (2.40e-1)" "potential prognostic favorable (1.55e-4)" "unprognostic (3.59e-1)" "unprognostic (8.78e-3)" "unprognostic (7.89e-2)" "unprognostic (1.76e-1)" "unprognostic (2.05e-2)" "unprognostic (8.48e-2)" "unprognostic (1.29e-1)" "unprognostic (3.38e-1)" "unprognostic (1.24e-2)" PIANP "C12orf53, DKFZp547D2210, PANP" ENSG00000139200 "PILR alpha associated neural protein" Q8IYJ0 12 6693791-6700815 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 143.4" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 31.9;Brain excitatory neurons: 29.8;Brain inhibitory neurons: 42.7;Corticotrophs: 10.8;Oligodendrocyte progenitor cells: 26.6;Other brain neurons: 46.9;Peritubular myoid cells: 13.2;Retinal amacrine cells: 18.0;Retinal bipolar cells: 8.7;Undifferentiated spermatogonia: 12.5" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 6 "Glioblastoma Multiforme (TCGA): 30.2;Testicular Germ Cell Tumor (TCGA): 16.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Neuroblastoma: 30.4" "Adrenal gland - Adrenal medulla cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010631 Enhanced Approved Nucleoplasm "Intracellular and membrane" "No annotated function" NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 98: Neurons - Neurotransmission & signaling" 4 Nucleoplasm "HPA010631: " "unprognostic (4.62e-2)" "unprognostic (5.80e-3)" "unprognostic (1.29e-3)" "unprognostic (4.57e-2)" "unprognostic (2.49e-2)" "unprognostic (1.47e-2)" "unprognostic (1.51e-2)" "unprognostic (4.38e-3)" "unprognostic (2.15e-3)" "unprognostic (4.53e-2)" "unprognostic (4.99e-1)" "unprognostic (2.10e-1)" "unprognostic (4.88e-2)" "unprognostic (1.42e-1)" "unprognostic (1.82e-1)" PIAS1 "DDXBP1, GBP, GU/RH-II, ZMIZ3" ENSG00000033800 "Protein inhibitor of activated STAT 1" O75925 15 68054309-68198603 "Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation, Ubl conjugation pathway" "DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 1313.0;Neutrophils: 1663.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Macrophages, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012304, HPA073610" Supported Uncertain Nucleoplasm,Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 116 Nucleoplasm Cytosol "CAB012304: , HPA073610: " "unprognostic (5.59e-3)" "unprognostic (8.17e-2)" "unprognostic (7.31e-2)" "unprognostic (3.04e-2)" "unprognostic (3.66e-1)" "unprognostic (3.67e-2)" "unprognostic (1.25e-1)" "unprognostic (9.55e-2)" "unprognostic (3.08e-1)" "unprognostic (2.43e-3)" "validated prognostic favorable (4.11e-8)" "validated prognostic favorable (1.16e-4)" "unprognostic (1.78e-1)" "unprognostic (5.20e-2)" "unprognostic (4.76e-2)" "unprognostic (1.20e-1)" "unprognostic (7.27e-2)" "unprognostic (9.61e-2)" "unprognostic (9.54e-2)" "unprognostic (8.59e-2)" "unprognostic (1.35e-1)" "unprognostic (6.79e-2)" "unprognostic (1.37e-2)" "unprognostic (2.85e-2)" "unprognostic (3.67e-2)" "unprognostic (6.64e-2)" "unprognostic (1.07e-1)" "unprognostic (2.28e-1)" "unprognostic (1.10e-1)" "unprognostic (1.19e-1)" "unprognostic (1.70e-1)" PIAS2 "ARIP3, miz, PIASX-ALPHA, PIASX-BETA, ZMIZ4" ENSG00000078043 "Protein inhibitor of activated STAT 2" O75928 18 46803218-46920160 "Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "testis: 62.8" "Cell type enhanced" "Detected in many" "Early spermatids: 533.7;Late primary spermatocytes: 548.0;Late spermatids: 799.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA068792, HPA077584" Enhanced Enhanced Nucleoplasm Yes No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 67: Testis - Mixed function" "Cluster 2: Neurons - Nucleosome" "Cluster 13: Non-specific - Mixed function" "Cluster 24: Neutrophils - Innate immunity signal integration" 55 Nucleoplasm "HPA068792: , HPA077584: " "unprognostic (5.95e-2)" "unprognostic (3.79e-1)" "unprognostic (8.96e-2)" "unprognostic (2.04e-1)" "unprognostic (3.11e-2)" "unprognostic (4.65e-1)" "unprognostic (1.80e-1)" "unprognostic (2.62e-3)" "unprognostic (1.41e-1)" "unprognostic (1.56e-2)" "unprognostic (1.79e-2)" "potential prognostic favorable (9.48e-4)" "unprognostic (1.83e-3)" "unprognostic (1.30e-3)" "unprognostic (1.31e-2)" "unprognostic (9.87e-2)" "unprognostic (1.17e-1)" "unprognostic (4.92e-2)" "unprognostic (6.02e-3)" "unprognostic (4.61e-2)" "unprognostic (1.62e-1)" "unprognostic (1.83e-2)" "unprognostic (4.12e-2)" "unprognostic (4.11e-2)" "unprognostic (8.32e-2)" "unprognostic (1.91e-1)" "unprognostic (5.41e-2)" "unprognostic (2.43e-1)" "unprognostic (1.66e-2)" "unprognostic (8.71e-3)" "unprognostic (7.10e-2)" PIAS3 "FLJ14651, ZMIZ5" ENSG00000131788 "Protein inhibitor of activated STAT 3" Q9Y6X2 1 145848522-145859836 "Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal suprabasal cells: 51.0;Fallopian tube ciliated cells: 50.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006389, HPA067383" Approved Supported Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 46: Brainstem - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 85: Squamous epithelial cells - Keratinization" 29 Nucleoplasm "HPA006389: , HPA067383: " "unprognostic (1.22e-1)" "unprognostic (1.85e-1)" "unprognostic (1.14e-1)" "unprognostic (5.10e-3)" "unprognostic (3.17e-1)" "unprognostic (8.29e-2)" "unprognostic (2.99e-2)" "unprognostic (2.31e-1)" "unprognostic (1.22e-1)" "unprognostic (6.07e-3)" "unprognostic (4.10e-3)" "unprognostic (4.02e-1)" "unprognostic (2.28e-2)" "potential prognostic unfavorable (5.83e-4)" "unprognostic (2.00e-1)" "unprognostic (1.05e-1)" "unprognostic (3.73e-2)" "unprognostic (7.71e-3)" "unprognostic (2.16e-1)" "unprognostic (1.43e-1)" "unprognostic (6.89e-2)" "unprognostic (2.97e-3)" "unprognostic (1.80e-2)" "unprognostic (7.87e-2)" "unprognostic (1.07e-1)" "unprognostic (4.03e-1)" "unprognostic (2.44e-2)" "unprognostic (1.86e-1)" "unprognostic (1.80e-1)" "unprognostic (6.72e-2)" "unprognostic (3.56e-1)" PIAS4 "FLJ12419, Piasg, PIASY, ZMIZ6" ENSG00000105229 "Protein inhibitor of activated STAT 4" Q8N2W9 19 4007736-4039386 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway, Wnt signaling pathway" "DNA-binding, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 86.0;Late primary spermatocytes: 147.2;Late spermatids: 409.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010598, HPA076008" Enhanced Supported Nucleoplasm,Centrosome NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 67: Testis - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 23: Non-specific - Transcription" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 83 Nucleoplasm Centrosome "HPA010598: , HPA076008: " "unprognostic (1.06e-1)" "unprognostic (8.98e-2)" "unprognostic (2.30e-1)" "unprognostic (5.44e-2)" "unprognostic (2.31e-1)" "unprognostic (1.25e-1)" "unprognostic (2.19e-1)" "unprognostic (4.47e-2)" "unprognostic (9.30e-3)" "unprognostic (1.13e-1)" "unprognostic (8.60e-3)" "unprognostic (4.50e-2)" "unprognostic (4.94e-1)" "unprognostic (1.87e-3)" "unprognostic (7.33e-2)" "unprognostic (1.31e-1)" "unprognostic (2.46e-1)" "unprognostic (2.63e-1)" "unprognostic (4.95e-2)" "unprognostic (2.68e-1)" "unprognostic (3.92e-3)" "unprognostic (4.35e-3)" "unprognostic (4.22e-2)" "unprognostic (2.25e-3)" "unprognostic (1.65e-1)" "unprognostic (2.04e-2)" "unprognostic (2.47e-1)" "unprognostic (1.70e-2)" "unprognostic (4.34e-2)" "unprognostic (3.37e-1)" "unprognostic (8.42e-3)" PIBF1 "C13orf24, CEP90, PIBF" ENSG00000083535 "Progesterone immunomodulatory binding factor 1" Q8WXW3 13 72782133-73016461 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Immunity "Ciliopathy, Disease variant, Joubert syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Choroid plexus epithelial cells: 567.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052269, HPA066120" Approved Supported "Centriolar satellite,Centrosome,Basal body" "Secreted to blood" Immunity NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 19: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 26 "Centriolar satellite, Centrosome" "Basal body" "HPA052269: , HPA066120: " "unprognostic (1.98e-2)" "unprognostic (3.11e-1)" "unprognostic (1.14e-1)" "unprognostic (2.54e-1)" "unprognostic (3.49e-1)" "unprognostic (2.05e-1)" "unprognostic (3.42e-1)" "unprognostic (1.50e-1)" "unprognostic (1.53e-2)" "unprognostic (1.30e-2)" "unprognostic (1.28e-2)" "unprognostic (5.04e-3)" "unprognostic (3.46e-1)" "unprognostic (2.07e-2)" "unprognostic (2.29e-1)" "unprognostic (1.94e-1)" "unprognostic (8.97e-2)" "unprognostic (8.21e-2)" "unprognostic (2.94e-2)" "unprognostic (1.46e-1)" "unprognostic (2.70e-2)" "unprognostic (1.60e-2)" "unprognostic (2.58e-2)" "unprognostic (2.51e-1)" "unprognostic (3.42e-1)" "unprognostic (3.45e-3)" "unprognostic (1.10e-2)" "unprognostic (1.94e-1)" "unprognostic (5.07e-3)" "unprognostic (1.05e-1)" "unprognostic (2.16e-1)" PICALM "CALM, CLTH" ENSG00000073921 "Phosphatidylinositol binding clathrin assembly protein" Q13492 11 85957175-86069882 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" Endocytosis "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglia: 1365.1;Neutrophils: 4206.8;Podocytes: 1194.0" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 1716.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 40.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019053, HPA019061" Enhanced Enhanced Vesicles NA NA 13000 "Cluster 7: Non-specific - Innate immune response" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 11: White matter - Signal transduction" "Cluster 47: Leukemia - Hemostasis" "Cluster 24: Neutrophils - Innate immunity signal integration" 45 Vesicles "HPA019053: , HPA019061: " "unprognostic (2.60e-1)" "unprognostic (1.28e-3)" "unprognostic (9.78e-2)" "potential prognostic unfavorable (9.94e-4)" "unprognostic (1.85e-1)" "unprognostic (1.73e-2)" "unprognostic (2.59e-1)" "unprognostic (1.58e-1)" "unprognostic (3.84e-1)" "unprognostic (1.58e-1)" "potential prognostic favorable (2.40e-9)" "unprognostic (2.52e-2)" "unprognostic (7.86e-2)" "unprognostic (5.33e-3)" "unprognostic (3.72e-1)" "unprognostic (1.66e-2)" "potential prognostic unfavorable (1.18e-5)" "unprognostic (1.47e-2)" "unprognostic (1.46e-2)" "unprognostic (4.54e-3)" "unprognostic (1.87e-2)" "unprognostic (2.50e-2)" "potential prognostic unfavorable (5.66e-4)" "unprognostic (4.79e-1)" "unprognostic (1.64e-2)" "unprognostic (1.16e-1)" "unprognostic (8.33e-2)" "unprognostic (6.45e-2)" "unprognostic (1.80e-1)" "unprognostic (2.31e-1)" "unprognostic (1.61e-1)" PICK1 "dJ1039K5, MGC15204, PRKCABP" ENSG00000100151 "Protein interacting with PRKCA 1" Q9NRD5 22 38056311-38075701 "Predicted intracellular proteins, Transporters" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 136.7;Late spermatids: 125.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Prostate - Prostate glandular cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000819, HPA072674" Approved Supported Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 331 Cytosol "HPA000819: , HPA072674: " "unprognostic (2.39e-1)" "unprognostic (3.28e-2)" "unprognostic (1.95e-1)" "unprognostic (1.11e-1)" "unprognostic (5.10e-3)" "unprognostic (3.81e-2)" "unprognostic (3.22e-2)" "unprognostic (1.15e-2)" "unprognostic (1.29e-1)" "unprognostic (4.83e-2)" "potential prognostic favorable (1.13e-4)" "unprognostic (6.81e-2)" "unprognostic (6.64e-3)" "unprognostic (5.01e-2)" "unprognostic (1.90e-1)" "unprognostic (2.68e-1)" "unprognostic (9.80e-2)" "unprognostic (1.39e-1)" "unprognostic (8.66e-3)" "unprognostic (1.10e-1)" "unprognostic (7.01e-2)" "unprognostic (1.89e-2)" "unprognostic (1.42e-1)" "unprognostic (1.84e-1)" "unprognostic (2.84e-2)" "unprognostic (1.15e-1)" "unprognostic (3.03e-1)" "unprognostic (3.62e-3)" "unprognostic (6.89e-2)" "unprognostic (2.38e-1)" "unprognostic (1.65e-2)" PID1 "FLJ20701, NYGGF4" ENSG00000153823 "Phosphotyrosine interaction domain containing 1" Q7Z2X4 2 228850526-229271287 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 90.8" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 479.8;Alveolar cells type 2: 395.3;cDC: 808.9;Fibro-adipogenic progenitors: 1153.7;Fibroblasts: 698.0;Hepatocytes: 690.1;Leydig cells: 588.8;Macrophages: 525.4;monocytes: 570.8;Oligodendrocyte progenitor cells: 1037.6;Thyrotrophs: 429.6" "Cell type enhanced" "Detected in all" "fibroblast: 1300.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 71.2;intermediate monocyte: 79.5;myeloid DC: 83.7" "Group enriched" "Detected in many" 52 "dendritic cells: 83.7;monocytes: 79.5" "Low cancer specificity" "Detected in many" "Colon - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatocytes, Prostate - Fibroblasts, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036103 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 103: Non-specific - Basic cellular processes" 11 "Endoplasmic reticulum" "HPA036103: " "unprognostic (6.49e-2)" "unprognostic (1.95e-1)" "unprognostic (4.11e-2)" "unprognostic (5.58e-2)" "unprognostic (3.01e-1)" "unprognostic (1.45e-1)" "unprognostic (1.73e-1)" "unprognostic (6.41e-3)" "unprognostic (1.18e-1)" "unprognostic (2.52e-3)" "potential prognostic favorable (4.99e-5)" "unprognostic (2.33e-1)" "potential prognostic unfavorable (8.69e-4)" "unprognostic (2.88e-3)" "unprognostic (2.30e-1)" "unprognostic (1.73e-2)" "unprognostic (4.60e-2)" "unprognostic (6.65e-2)" "unprognostic (2.10e-1)" "unprognostic (7.78e-2)" "unprognostic (1.26e-3)" "unprognostic (1.75e-1)" "unprognostic (1.92e-1)" "unprognostic (4.96e-2)" "potential prognostic favorable (5.47e-4)" "unprognostic (3.11e-1)" "unprognostic (2.88e-1)" "unprognostic (1.65e-2)" "unprognostic (1.08e-1)" "unprognostic (3.80e-2)" "unprognostic (3.30e-2)" PIDD1 "DKFZp434D229, LRDD, MGC16925, PIDD" ENSG00000177595 "P53-induced death domain protein 1" Q9HB75 11 799179-809753 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Apoptosis Hydrolase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 35.9;Early primary spermatocytes: 36.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB012647, HPA055473, HPA066948" Supported Approved "Golgi apparatus,Cytosol" NA Yes "Cluster 33: Non-specific - ATP binding" "Cluster 64: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 35: RS4;11 - Unknown function" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 13 "Golgi apparatus, Cytosol" "CAB012647: , HPA055473: , HPA066948: " "unprognostic (3.33e-2)" "unprognostic (1.36e-1)" "unprognostic (4.07e-2)" "unprognostic (1.19e-1)" "unprognostic (5.88e-2)" "unprognostic (7.13e-2)" "unprognostic (5.28e-2)" "unprognostic (1.39e-2)" "unprognostic (5.58e-3)" "unprognostic (8.47e-2)" "unprognostic (2.65e-2)" "unprognostic (4.48e-2)" "unprognostic (2.34e-3)" "unprognostic (6.56e-2)" "unprognostic (1.49e-1)" "unprognostic (2.28e-1)" "unprognostic (1.43e-3)" "unprognostic (1.05e-1)" "unprognostic (2.61e-2)" "unprognostic (8.58e-2)" "unprognostic (1.57e-1)" "unprognostic (2.04e-3)" "unprognostic (2.30e-1)" "unprognostic (2.48e-3)" "unprognostic (1.14e-1)" "unprognostic (1.63e-1)" "unprognostic (4.20e-1)" PIERCE1 "C9orf116, MGC29761, RbEST47" ENSG00000160345 "Piercer of microtubule wall 1" Q5BN46 9 135495181-135501734 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 57.7;fallopian tube: 91.4;testis: 59.7" "Group enriched" "Detected in many" 8 "Early spermatids: 430.3;Endometrial ciliated cells: 451.3;Epididymal efferent duct ciliated cells: 810.5;Fallopian tube ciliated cells: 827.9;Late primary spermatocytes: 533.3;Late spermatids: 685.5;Respiratory ciliated cells: 792.0" "Cell type enriched" "Detected in many" 5 "ependymal cell: 73.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA021439, HPA065287" Approved Uncertain "Nucleoplasm,Cytosol,Mid piece" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" 1 "Nucleoplasm, Mid piece" Cytosol "HPA021439: , HPA065287: " "unprognostic (2.22e-1)" "unprognostic (2.20e-1)" "unprognostic (1.51e-1)" "potential prognostic favorable (8.94e-4)" "unprognostic (9.19e-2)" "unprognostic (8.24e-2)" "unprognostic (6.48e-3)" "unprognostic (3.41e-3)" "unprognostic (3.72e-2)" "unprognostic (6.91e-2)" "unprognostic (1.30e-1)" "unprognostic (2.50e-1)" "potential prognostic favorable (5.21e-5)" "unprognostic (1.73e-1)" "unprognostic (3.16e-2)" "unprognostic (1.54e-1)" "unprognostic (4.54e-2)" "unprognostic (1.44e-1)" "unprognostic (1.95e-1)" "unprognostic (1.16e-1)" "unprognostic (2.80e-2)" "unprognostic (1.05e-1)" "unprognostic (1.04e-1)" "unprognostic (1.11e-1)" "unprognostic (2.33e-1)" "unprognostic (1.27e-2)" "unprognostic (3.12e-1)" "unprognostic (6.37e-2)" "unprognostic (7.28e-2)" "unprognostic (3.80e-2)" "unprognostic (8.31e-3)" PIERCE2 "C15orf65, FLJ27352" ENSG00000261652 "Piercer of microtubule wall 2" H3BRN8 15 55408495-55418798 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 167.8;Endometrial ciliated cells: 91.2;Epididymal efferent duct ciliated cells: 83.1;Fallopian tube ciliated cells: 83.2;Late primary spermatocytes: 171.9;Respiratory ciliated cells: 98.1" "Cell type enhanced" "Detected in many" "ependymal cell: 50.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 4.7" "Lineage enriched" "Detected in single" 5 "granulocytes: 4.7" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Stomach - Chief cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067189 Approved NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 107: Ciliated cells - Cilia assembly & function" 1 "HPA067189: " "unprognostic (1.42e-2)" "unprognostic (8.95e-3)" "unprognostic (6.00e-2)" "unprognostic (3.78e-1)" "unprognostic (1.95e-3)" "unprognostic (1.12e-1)" "unprognostic (2.43e-3)" "unprognostic (1.94e-2)" "unprognostic (1.45e-1)" "unprognostic (1.31e-1)" "unprognostic (3.18e-1)" "unprognostic (3.79e-2)" "potential prognostic unfavorable (4.63e-6)" "unprognostic (4.04e-1)" "unprognostic (3.90e-2)" "unprognostic (8.63e-3)" "unprognostic (7.43e-2)" "unprognostic (2.25e-1)" "unprognostic (1.98e-1)" "unprognostic (6.07e-2)" "unprognostic (2.53e-1)" "unprognostic (2.35e-1)" "unprognostic (7.52e-2)" "unprognostic (1.04e-2)" "unprognostic (9.25e-2)" "unprognostic (1.11e-1)" "unprognostic (1.75e-1)" "unprognostic (1.14e-1)" "unprognostic (5.24e-2)" PIEZO1 "FAM38A, KIAA0233" ENSG00000103335 "Piezo type mechanosensitive ion channel component 1" Q92508 16 88715338-88785220 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Blood group antigen, Ion channel" "Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 101.6;Lymphatic endothelial cells: 134.1;Renal collecting duct principal cells: 115.1" "Cell type enhanced" "Detected in many" "astrocyte: 44.5;central nervous system macrophage: 60.8;endothelial cell: 57.4;leukocyte: 64.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Pituitary gland - Endothelial cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA047185 Uncertain NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 74: Non-specific - Signal transduction" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 2 "HPA047185: " "unprognostic (5.37e-2)" "unprognostic (3.75e-1)" "unprognostic (3.59e-2)" "unprognostic (3.02e-3)" "unprognostic (2.28e-2)" "unprognostic (2.81e-2)" "unprognostic (2.19e-3)" "unprognostic (7.55e-2)" "unprognostic (2.92e-1)" "unprognostic (1.96e-2)" "unprognostic (1.11e-1)" "unprognostic (2.72e-2)" "unprognostic (4.23e-3)" "unprognostic (2.79e-3)" "unprognostic (1.63e-1)" "unprognostic (6.76e-3)" "unprognostic (7.04e-2)" "potential prognostic unfavorable (5.99e-5)" "unprognostic (5.93e-2)" "unprognostic (9.32e-2)" "unprognostic (3.33e-3)" "unprognostic (3.80e-1)" "unprognostic (1.74e-1)" "unprognostic (2.84e-2)" "unprognostic (1.81e-1)" "unprognostic (2.88e-2)" "unprognostic (4.09e-2)" "unprognostic (4.00e-2)" "unprognostic (5.10e-2)" PIEZO2 "C18orf30, C18orf58, FAM38B, FAM38B2, FLJ23144, FLJ23403, FLJ34907, HsT748, HsT771" ENSG00000154864 "Piezo type mechanosensitive ion channel component 2" Q9H5I5 18 10666483-11149569 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Transport" "Ion channel" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibro-adipogenic progenitors: 70.2;Gonadotrophs: 161.3;Lymphatic endothelial cells: 343.5;Megakaryocyte progenitors: 220.0;Mesothelial cells: 156.9;Oligodendrocytes: 400.4;Pancreatic acinar cells: 72.3" "Cell type enriched" "Detected in many" 4 "oligodendrocyte: 586.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 22.3;liver cancer: 17.2" "Colon - Enteric glia cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA015986, HPA031974, HPA040616" Approved Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 13: Lung - Secretion" "Cluster 11: White matter - Signal transduction" "Cluster 72: Neuronal - Signal transduction" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "Plasma membrane" "Vesicles, Cytosol" "HPA015986: , HPA031974: , HPA040616: " "unprognostic (3.03e-1)" "unprognostic (4.40e-1)" "unprognostic (2.94e-1)" "unprognostic (1.27e-1)" "unprognostic (5.90e-3)" "unprognostic (1.30e-2)" "potential prognostic favorable (8.23e-6)" "unprognostic (9.54e-3)" "unprognostic (1.21e-3)" "unprognostic (5.69e-2)" "unprognostic (1.07e-2)" "unprognostic (2.33e-1)" "unprognostic (3.52e-2)" "unprognostic (1.68e-1)" "unprognostic (2.94e-2)" "unprognostic (6.47e-3)" "unprognostic (3.98e-1)" "unprognostic (2.90e-2)" "unprognostic (5.20e-2)" "potential prognostic unfavorable (8.15e-5)" "unprognostic (1.47e-1)" "unprognostic (1.78e-2)" PIF1 "C15orf20, FLJ22692" ENSG00000140451 "PIF1 5'-to-3' DNA helicase" Q9H611 15 64815632-64825668 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" "DNA-binding, Helicase, Hydrolase, Isomerase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 4.6" "Cell type enhanced" "Detected in many" "Early spermatids: 29.5;Enteric transient amplifying cells: 12.7;Esophageal basal cells: 12.1;Hofbauer cells: 8.8;Megakaryocyte progenitors: 13.0;Monocyte progenitors: 21.0;NK-cells: 11.2;Plasma cells: 19.9" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 19.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Mitotic cells (Minor salivary gland), Prostate - Fibroblasts, Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach)" "Not detected" "Not detected" "Not detected" "Not detected" CAB018701 Supported Supported Nucleoplasm NA Yes "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 1: Neurons - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 27: Non-specific - Cell proliferation" Nucleoplasm "CAB018701: " "unprognostic (1.15e-2)" "unprognostic (2.08e-1)" "unprognostic (3.59e-1)" "unprognostic (1.17e-1)" "unprognostic (9.62e-2)" "unprognostic (1.39e-1)" "unprognostic (2.43e-1)" "unprognostic (1.04e-2)" "unprognostic (7.44e-3)" "validated prognostic unfavorable (4.70e-4)" "validated prognostic unfavorable (4.70e-6)" "unprognostic (2.71e-3)" "potential prognostic unfavorable (5.55e-4)" "unprognostic (7.36e-2)" "unprognostic (9.38e-2)" "unprognostic (1.98e-1)" "unprognostic (1.60e-2)" "unprognostic (6.65e-2)" "potential prognostic unfavorable (8.42e-4)" "unprognostic (3.32e-2)" "potential prognostic favorable (2.61e-4)" "potential prognostic unfavorable (8.81e-4)" "unprognostic (2.71e-3)" "unprognostic (2.73e-1)" "unprognostic (3.42e-2)" PIFO "C1orf88, FLJ23853, pitchfork" ENSG00000173947 "Primary cilia formation" Q8TCI5 1 111346600-111353013 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "choroid plexus: 134.0;fallopian tube: 163.8" "Cell type enhanced" "Detected in many" "Early spermatids: 494.8;Endometrial ciliated cells: 542.0;Epididymal efferent duct ciliated cells: 681.6;Fallopian tube ciliated cells: 1264.9;Late primary spermatocytes: 270.5;Late spermatids: 642.0;Respiratory ciliated cells: 949.1" "Group enriched" "Detected in many" 12 "choroid plexus epithelial cell: 76.6;ependymal cell: 179.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "choroid plexus: 65.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Bile duct cancer: 8.4;testis cancer: 7.3" "Breast - Breast myoepithelial cells, Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Stomach - Chief cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA079487 Approved Vesicles NA NA "Cluster 24: Non-specific - Transcription" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" Vesicles "HPA079487: " "unprognostic (1.86e-1)" "unprognostic (1.61e-1)" "unprognostic (4.22e-2)" "unprognostic (1.53e-1)" "unprognostic (3.93e-2)" "unprognostic (1.54e-2)" "potential prognostic unfavorable (1.73e-4)" "unprognostic (1.81e-1)" "potential prognostic favorable (1.75e-7)" "unprognostic (2.74e-3)" "potential prognostic favorable (3.33e-5)" "unprognostic (1.39e-3)" "unprognostic (9.54e-2)" "unprognostic (3.14e-3)" "unprognostic (8.41e-2)" "unprognostic (1.66e-2)" "unprognostic (1.98e-2)" "potential prognostic favorable (4.27e-4)" "unprognostic (2.20e-2)" "unprognostic (2.84e-1)" "unprognostic (2.07e-1)" "unprognostic (5.27e-2)" "unprognostic (1.51e-3)" "unprognostic (2.97e-3)" "unprognostic (1.39e-1)" "unprognostic (4.75e-1)" "unprognostic (3.03e-1)" PIGA "GPI3, PIG-A" ENSG00000165195 "Phosphatidylinositol glycan anchor biosynthesis class A" P37287 X 15319452-15335554 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis, Lipid metabolism" "Glycosyltransferase, Transferase" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 142.3;Endometrial glandular cells: 100.3;Esophageal suprabasal cells: 92.5;Transitional alveolar cells: 113.5;Urothelial cells: 121.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 23.4" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001174 Approved NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 36: Non-specific - mRNA processing" "Cluster 103: Non-specific - Basic cellular processes" 12 "HPA001174: " "unprognostic (1.42e-1)" "unprognostic (4.71e-3)" "unprognostic (8.83e-2)" "unprognostic (2.19e-1)" "unprognostic (7.43e-2)" "unprognostic (1.14e-1)" "unprognostic (1.67e-1)" "unprognostic (2.89e-1)" "unprognostic (1.42e-1)" "unprognostic (2.14e-1)" "potential prognostic favorable (1.04e-6)" "unprognostic (1.19e-2)" "unprognostic (1.83e-1)" "unprognostic (2.31e-2)" "unprognostic (8.12e-2)" "unprognostic (5.13e-2)" "unprognostic (1.56e-1)" "unprognostic (2.88e-1)" "unprognostic (5.19e-1)" "unprognostic (2.05e-1)" "unprognostic (3.44e-3)" "unprognostic (1.29e-2)" "unprognostic (2.64e-1)" "unprognostic (2.96e-1)" "unprognostic (4.14e-2)" "unprognostic (1.51e-1)" "unprognostic (4.79e-2)" "unprognostic (1.77e-1)" "unprognostic (6.15e-3)" "unprognostic (2.65e-2)" PIGB ENSG00000069943 "Phosphatidylinositol glycan anchor biosynthesis class B" Q92521 15 55318960-55355648 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Glycosyltransferase, Transferase" Epilepsy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 131.7;Neutrophil progenitors: 89.2;Neutrophils: 112.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039929 Uncertain Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 22: Epididymis - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 58: Non-specific - Nuclear processes" "Cluster 24: Neutrophils - Innate immunity signal integration" "Plasma membrane, Cytosol" "HPA039929: " "unprognostic (8.97e-2)" "unprognostic (1.25e-1)" "unprognostic (8.91e-3)" "unprognostic (1.39e-1)" "unprognostic (2.65e-1)" "unprognostic (1.92e-1)" "unprognostic (9.24e-3)" "potential prognostic unfavorable (2.43e-4)" "unprognostic (2.16e-2)" "unprognostic (3.49e-2)" "potential prognostic favorable (2.31e-6)" "unprognostic (6.91e-2)" "unprognostic (1.89e-1)" "unprognostic (2.27e-1)" "unprognostic (1.91e-3)" "unprognostic (2.40e-3)" "unprognostic (7.75e-2)" "unprognostic (1.52e-1)" "unprognostic (1.29e-1)" "unprognostic (1.01e-1)" "unprognostic (2.15e-1)" "unprognostic (9.65e-3)" "unprognostic (2.43e-2)" "unprognostic (6.70e-2)" "unprognostic (1.00e-1)" "unprognostic (2.00e-1)" "unprognostic (1.91e-2)" "unprognostic (1.95e-1)" "unprognostic (3.43e-1)" "unprognostic (8.85e-2)" "unprognostic (1.12e-1)" PIGBOS1 ENSG00000225973 "PIGB opposite strand 1" A0A0B4J2F0 15 55317184-55319161 "Predicted intracellular proteins" "Unfolded protein response" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Tuft cells: 23.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 17: Non-specific - RNA processing" 1 "unprognostic (2.03e-1)" "unprognostic (1.04e-1)" "unprognostic (2.19e-2)" "unprognostic (8.07e-2)" "unprognostic (1.22e-1)" "potential prognostic unfavorable (9.85e-4)" "unprognostic (2.40e-1)" "unprognostic (1.18e-1)" "potential prognostic unfavorable (2.29e-5)" "unprognostic (9.21e-2)" "unprognostic (8.87e-2)" "unprognostic (1.28e-1)" "unprognostic (8.35e-2)" "unprognostic (5.07e-2)" "unprognostic (2.72e-1)" "unprognostic (9.16e-2)" "unprognostic (4.97e-2)" "unprognostic (7.65e-2)" "unprognostic (1.93e-1)" "unprognostic (1.14e-1)" "unprognostic (8.10e-2)" "unprognostic (6.07e-2)" "unprognostic (2.98e-1)" "unprognostic (1.98e-1)" "unprognostic (1.83e-2)" "unprognostic (4.00e-2)" "unprognostic (1.73e-1)" "unprognostic (2.79e-1)" "unprognostic (3.26e-2)" PIGC ENSG00000135845 "Phosphatidylinositol glycan anchor biosynthesis class C" Q92535 1 172370189-172444086 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 121.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036663 Uncertain NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 58: Skin - Keratinization" "Cluster 27: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 80: Oligodendrocytes - Myelination" 4 "HPA036663: " "unprognostic (8.75e-3)" "unprognostic (1.07e-1)" "unprognostic (1.51e-1)" "unprognostic (7.56e-2)" "unprognostic (1.22e-1)" "unprognostic (1.24e-1)" "unprognostic (1.29e-1)" "unprognostic (2.57e-1)" "unprognostic (2.80e-2)" "unprognostic (8.43e-3)" "unprognostic (4.62e-3)" "unprognostic (1.46e-2)" "potential prognostic unfavorable (9.84e-7)" "potential prognostic unfavorable (7.00e-4)" "unprognostic (5.19e-2)" "unprognostic (7.32e-2)" "unprognostic (1.97e-1)" "unprognostic (6.61e-2)" "unprognostic (1.45e-2)" "unprognostic (7.08e-2)" "unprognostic (1.13e-2)" "unprognostic (9.92e-3)" "unprognostic (2.68e-1)" "unprognostic (1.94e-1)" "unprognostic (1.57e-1)" "unprognostic (2.66e-2)" "unprognostic (1.16e-2)" "unprognostic (3.31e-3)" "unprognostic (2.60e-1)" "unprognostic (7.78e-2)" "unprognostic (6.39e-2)" PIGF ENSG00000151665 "Phosphatidylinositol glycan anchor biosynthesis class F" Q07326 2 46580937-46617055 "Disease related genes, Metabolic proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 290.4;Epicardial cells: 247.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051389 Uncertain NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 8 "HPA051389: " "unprognostic (6.62e-2)" "unprognostic (5.22e-3)" "unprognostic (1.54e-2)" "unprognostic (2.53e-2)" "unprognostic (3.92e-2)" "unprognostic (1.83e-1)" "unprognostic (2.13e-1)" "unprognostic (9.84e-2)" "unprognostic (7.48e-3)" "unprognostic (3.82e-2)" "potential prognostic favorable (4.58e-6)" "unprognostic (1.30e-2)" "unprognostic (1.51e-1)" "validated prognostic unfavorable (8.08e-6)" "validated prognostic unfavorable (6.44e-6)" "unprognostic (5.51e-2)" "unprognostic (6.68e-2)" "unprognostic (6.22e-2)" "unprognostic (1.19e-1)" "unprognostic (2.24e-1)" "unprognostic (1.12e-1)" "unprognostic (1.13e-2)" "unprognostic (8.92e-2)" "unprognostic (1.05e-1)" "unprognostic (1.04e-1)" "unprognostic (3.08e-1)" "unprognostic (1.76e-1)" "unprognostic (2.75e-1)" "unprognostic (1.37e-1)" "unprognostic (1.21e-1)" "unprognostic (2.69e-1)" PIGG "FLJ20265, GPI7, LAS21" ENSG00000174227 "Phosphatidylinositol glycan anchor biosynthesis class G" Q5H8A4 4 499210-540200 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" Transferase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015997 Uncertain NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 17: Intestine - Digestion" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 7: Non-specific - Transcription" 3 "HPA015997: " "unprognostic (4.28e-1)" "unprognostic (2.78e-1)" "unprognostic (1.59e-1)" "potential prognostic unfavorable (1.39e-4)" "unprognostic (6.25e-3)" "unprognostic (2.71e-2)" "unprognostic (1.29e-1)" "unprognostic (2.08e-1)" "unprognostic (2.80e-1)" "unprognostic (3.41e-1)" "potential prognostic favorable (1.08e-5)" "unprognostic (1.72e-3)" "unprognostic (1.78e-1)" "unprognostic (3.15e-3)" "unprognostic (1.59e-2)" "unprognostic (1.28e-1)" "unprognostic (1.53e-1)" "unprognostic (2.39e-2)" "unprognostic (1.03e-1)" "unprognostic (2.34e-1)" "unprognostic (1.06e-1)" "unprognostic (1.31e-1)" "unprognostic (1.85e-2)" "unprognostic (1.36e-1)" "unprognostic (7.37e-3)" "unprognostic (1.61e-3)" "unprognostic (1.20e-1)" "unprognostic (2.26e-2)" "unprognostic (4.99e-1)" "unprognostic (4.22e-2)" "unprognostic (2.50e-1)" PIGH GPI-H ENSG00000100564 "Phosphatidylinositol glycan anchor biosynthesis class H" Q14442 14 67581955-67600286 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Autism spectrum disorder, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 101.3;Syncytiotrophoblasts: 97.4" "Cell type enhanced" "Detected in all" "oligodendrocyte: 92.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031624 Approved NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 80: Oligodendrocytes - Myelination" 97 "HPA031624: " "unprognostic (5.60e-2)" "unprognostic (1.10e-1)" "unprognostic (1.11e-1)" "unprognostic (1.96e-1)" "unprognostic (1.71e-1)" "unprognostic (1.82e-1)" "unprognostic (1.57e-1)" "unprognostic (1.53e-1)" "unprognostic (7.84e-2)" "unprognostic (1.77e-1)" "potential prognostic favorable (1.88e-7)" "unprognostic (3.31e-3)" "unprognostic (1.11e-2)" "unprognostic (5.34e-3)" "unprognostic (6.28e-2)" "unprognostic (2.51e-1)" "unprognostic (6.94e-3)" "unprognostic (1.71e-2)" "unprognostic (2.51e-2)" "unprognostic (2.90e-1)" "unprognostic (2.25e-1)" "unprognostic (4.78e-2)" "unprognostic (3.05e-2)" "unprognostic (8.66e-2)" "unprognostic (3.33e-1)" "unprognostic (8.97e-3)" "unprognostic (3.01e-1)" "unprognostic (5.70e-2)" "unprognostic (3.75e-2)" "unprognostic (2.00e-1)" "unprognostic (3.87e-3)" PIGK "GPI8, hGPI8" ENSG00000142892 "Phosphatidylinositol glycan anchor biosynthesis class K" Q92643 1 77088989-77219430 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" Transferase "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 119.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056383, HPA057040" Uncertain "Intracellular and membrane" Enzyme NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 3: Early primary spermatocytes - Early meiosis" 39 "HPA056383: , HPA057040: " "unprognostic (2.01e-2)" "unprognostic (1.58e-1)" "unprognostic (2.91e-1)" "unprognostic (8.05e-2)" "unprognostic (2.85e-2)" "unprognostic (2.15e-1)" "unprognostic (3.63e-1)" "unprognostic (1.32e-3)" "unprognostic (1.21e-1)" "unprognostic (4.70e-2)" "potential prognostic favorable (1.83e-6)" "unprognostic (1.02e-1)" "unprognostic (9.80e-2)" "potential prognostic unfavorable (3.49e-4)" "unprognostic (1.04e-2)" "unprognostic (5.96e-3)" "unprognostic (1.11e-2)" "unprognostic (2.80e-1)" "unprognostic (1.47e-1)" "unprognostic (8.10e-2)" "unprognostic (9.83e-3)" "unprognostic (5.93e-2)" "unprognostic (1.93e-1)" "unprognostic (8.58e-2)" "unprognostic (8.71e-2)" "unprognostic (1.93e-1)" "unprognostic (4.09e-1)" "unprognostic (2.27e-2)" "unprognostic (2.33e-1)" "unprognostic (7.77e-2)" "unprognostic (5.75e-2)" PIGL ENSG00000108474 "Phosphatidylinositol glycan anchor biosynthesis class L" Q9Y2B2 17 16217191-16351797 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "GPI-anchor biosynthesis, Lipid metabolism" Hydrolase "Deafness, Disease variant, Ichthyosis, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012739 Approved Approved Nucleoplasm,Cytosol No No "Cluster 3: Non-specific - Nuclear processes" "Cluster 70: Non-specific - Protein processing" "Cluster 31: Non-specific - Transcription" "Cluster 42: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 2 "Nucleoplasm, Cytosol" "HPA012739: " "unprognostic (2.42e-1)" "unprognostic (1.60e-1)" "unprognostic (8.38e-2)" "unprognostic (1.13e-1)" "unprognostic (1.35e-1)" "unprognostic (4.78e-3)" "unprognostic (2.31e-2)" "unprognostic (7.93e-3)" "unprognostic (8.79e-2)" "unprognostic (1.18e-2)" "unprognostic (9.46e-3)" "unprognostic (3.37e-2)" "unprognostic (5.95e-2)" "unprognostic (5.23e-2)" "unprognostic (1.48e-1)" "unprognostic (1.50e-1)" "unprognostic (3.26e-1)" "unprognostic (1.40e-1)" "unprognostic (1.70e-1)" "unprognostic (1.80e-2)" "unprognostic (1.07e-1)" "unprognostic (1.55e-2)" "unprognostic (4.10e-3)" "potential prognostic unfavorable (1.97e-4)" "unprognostic (7.99e-3)" "unprognostic (1.33e-1)" "unprognostic (2.58e-3)" "unprognostic (7.30e-2)" "unprognostic (1.26e-1)" "unprognostic (3.16e-1)" "unprognostic (6.39e-2)" PIGM GPI-MT-I ENSG00000143315 "Phosphatidylinositol glycan anchor biosynthesis class M" Q9H3S5 1 160024953-160031990 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" HPA047418 Uncertain NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 30: White matter - Myelination" "Cluster 45: Non-specific - Nuclear processes" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 4 "HPA047418: " "unprognostic (7.28e-3)" "unprognostic (1.42e-2)" "unprognostic (1.25e-1)" "unprognostic (2.05e-2)" "unprognostic (4.77e-2)" "unprognostic (2.91e-1)" "unprognostic (3.49e-1)" "unprognostic (3.82e-2)" "unprognostic (7.31e-2)" "unprognostic (4.46e-2)" "unprognostic (6.20e-3)" "unprognostic (6.37e-2)" "unprognostic (1.25e-1)" "unprognostic (1.68e-2)" "unprognostic (2.49e-1)" "unprognostic (7.51e-2)" "unprognostic (9.89e-2)" "unprognostic (6.34e-2)" "unprognostic (5.06e-2)" "unprognostic (2.26e-1)" "unprognostic (1.52e-2)" "unprognostic (2.01e-2)" "unprognostic (1.26e-1)" "unprognostic (1.20e-1)" "unprognostic (2.31e-2)" "unprognostic (7.65e-2)" "unprognostic (8.02e-2)" "unprognostic (6.29e-2)" "unprognostic (1.99e-1)" "unprognostic (9.15e-2)" "unprognostic (1.72e-1)" PIGN "MCD4, PIG-N" ENSG00000197563 "Phosphatidylinositol glycan anchor biosynthesis class N" O95427 18 61905255-62187118 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" Transferase "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Parietal cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039922, HPA040374" Approved Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 42: Retina - Visual perception" "Cluster 9: Non-specific - Receptor signaling" "Cluster 13: Non-specific - Mixed function" "Cluster 7: Non-specific - Transcription" 14 "Plasma membrane, Cytosol" "HPA039922: , HPA040374: " "unprognostic (1.02e-1)" "unprognostic (6.78e-3)" "unprognostic (1.18e-1)" "unprognostic (1.04e-1)" "unprognostic (9.36e-3)" "unprognostic (1.35e-1)" "unprognostic (3.14e-1)" "unprognostic (6.56e-2)" "unprognostic (2.75e-1)" "potential prognostic unfavorable (9.07e-7)" "unprognostic (7.05e-2)" "unprognostic (1.52e-2)" "unprognostic (1.82e-1)" "unprognostic (7.48e-2)" "unprognostic (8.51e-2)" "unprognostic (8.26e-2)" "unprognostic (2.78e-1)" "unprognostic (8.81e-2)" "unprognostic (1.36e-1)" "unprognostic (2.37e-1)" "unprognostic (2.40e-3)" "unprognostic (2.39e-2)" "unprognostic (2.59e-1)" "unprognostic (2.18e-1)" "unprognostic (1.11e-2)" "unprognostic (4.01e-2)" "unprognostic (7.90e-2)" "unprognostic (9.36e-2)" "unprognostic (1.78e-1)" "unprognostic (5.86e-2)" "unprognostic (2.22e-1)" PIGO "DKFZp434M222, FLJ00135" ENSG00000165282 "Phosphatidylinositol glycan anchor biosynthesis class O" Q8TEQ8 9 35087237-35096619 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" Transferase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate basal glandular cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014905 Approved Nucleoplasm,Nucleoli NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 62: Non-specific - Plasma proteins" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 6 Nucleoli Nucleoplasm "HPA014905: " "unprognostic (2.54e-1)" "unprognostic (3.27e-2)" "unprognostic (1.10e-1)" "unprognostic (1.99e-1)" "unprognostic (3.16e-1)" "unprognostic (6.87e-2)" "unprognostic (1.94e-1)" "unprognostic (2.88e-1)" "unprognostic (3.03e-1)" "unprognostic (1.90e-1)" "validated prognostic favorable (1.38e-9)" "validated prognostic favorable (9.01e-4)" "unprognostic (5.81e-2)" "unprognostic (9.53e-3)" "unprognostic (9.81e-2)" "unprognostic (5.46e-2)" "unprognostic (2.56e-3)" "unprognostic (2.13e-1)" "unprognostic (2.12e-1)" "unprognostic (2.51e-1)" "unprognostic (3.34e-1)" "unprognostic (2.40e-1)" "unprognostic (2.17e-1)" "unprognostic (1.14e-1)" "unprognostic (1.59e-1)" "unprognostic (2.86e-1)" "unprognostic (2.06e-1)" "unprognostic (1.50e-1)" "unprognostic (4.62e-2)" "unprognostic (4.21e-2)" "unprognostic (3.64e-1)" PIGP "DCRC, DSCR5, DSRC" ENSG00000185808 "Phosphatidylinositol glycan anchor biosynthesis class P" P57054 21 37062846-37073170 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 416.1;Epididymal principal cells: 307.9;Gastric chief cells: 191.1;Oocytes: 188.8;Parietal cells: 224.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026921 Uncertain Approved Vesicles Yes No "Cluster 30: Non-specific - DNA binding" "Cluster 22: Epididymis - Mixed function" "Cluster 30: White matter - Myelination" "Cluster 47: Leukemia - Hemostasis" "Cluster 3: Early primary spermatocytes - Early meiosis" 21 Vesicles "HPA026921: " "unprognostic (1.56e-1)" "potential prognostic unfavorable (8.41e-4)" "unprognostic (9.54e-3)" "unprognostic (5.20e-2)" "unprognostic (3.55e-1)" "unprognostic (6.19e-2)" "unprognostic (5.82e-3)" "unprognostic (9.72e-2)" "potential prognostic unfavorable (5.88e-4)" "unprognostic (2.95e-1)" "potential prognostic favorable (3.09e-5)" "unprognostic (4.76e-2)" "unprognostic (9.85e-2)" "unprognostic (8.50e-2)" "unprognostic (2.90e-1)" "unprognostic (1.55e-2)" "unprognostic (1.86e-1)" "unprognostic (2.86e-2)" "unprognostic (5.14e-2)" "unprognostic (1.42e-1)" "unprognostic (5.87e-2)" "unprognostic (3.84e-3)" "unprognostic (9.60e-2)" "unprognostic (6.89e-2)" "unprognostic (1.22e-3)" "unprognostic (1.96e-1)" "unprognostic (1.49e-1)" "unprognostic (2.56e-2)" "unprognostic (8.52e-2)" "unprognostic (2.14e-1)" "unprognostic (2.63e-1)" PIGQ "GPI1, hGPI1" ENSG00000007541 "Phosphatidylinositol glycan anchor biosynthesis class Q" Q9BRB3 16 566995-584109 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 108.3;Renal collecting duct principal cells: 69.0;Renal connecting tubule cells: 80.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039105, HPA039828, HPA061414" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 24: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 10 "Golgi apparatus, Vesicles" Nucleoplasm "HPA039105: , HPA039828: , HPA061414: " "unprognostic (9.74e-3)" "unprognostic (6.83e-2)" "unprognostic (4.99e-2)" "unprognostic (5.27e-2)" "unprognostic (8.41e-2)" "unprognostic (1.83e-1)" "unprognostic (3.01e-1)" "unprognostic (1.84e-1)" "unprognostic (1.62e-1)" "unprognostic (5.75e-3)" "potential prognostic favorable (4.84e-4)" "unprognostic (7.96e-2)" "unprognostic (6.76e-2)" "unprognostic (6.74e-2)" "unprognostic (2.29e-2)" "unprognostic (2.60e-2)" "unprognostic (1.13e-1)" "unprognostic (2.37e-2)" "unprognostic (5.40e-2)" "unprognostic (4.02e-1)" "unprognostic (3.23e-1)" "unprognostic (4.03e-2)" "unprognostic (5.08e-1)" "unprognostic (2.77e-1)" "unprognostic (4.30e-2)" "unprognostic (3.52e-3)" "unprognostic (5.11e-2)" "unprognostic (2.16e-1)" "unprognostic (3.72e-1)" "unprognostic (5.27e-2)" "unprognostic (7.64e-2)" PIGR ENSG00000162896 "Polymeric immunoglobulin receptor" P01833 1 206928522-206946466 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 2479.3;salivary gland: 1544.3" "Cell type enhanced" "Detected in many" "Breast lactating cells: 1662.6;Colonocytes: 8431.4;Conjunctival goblet cells: 1998.0;Endometrial secretory cells: 1554.4;Enteric stem cells: 3464.7;Enteric transient amplifying cells: 4471.2;Goblet cells: 1754.4;Lacrimal acinar cells: 5520.1;Mucous neck cells: 1810.3;Paneth cells: 1945.3;Prostatic club cells: 2770.1;Salivary acinar cells: 2959.2;Submucosal glandular cells: 1761.7" "Cell type enhanced" "Detected in single" "leukocyte: 1.2" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 838.6;Kidney Renal Papillary Cell Carcinoma (TCGA): 881.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Bile duct cancer: 29.7;colorectal cancer: 30.9;Gastric cancer: 55.5" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Stomach - Mitotic cells (Stomach)" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA006154, CAB009454, HPA012012" Enhanced "Secreted to digestive system" "No annotated function" NA NA 200000000 "Cluster 77: Intestine - Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 23 "CAB009454: , HPA006154: , HPA012012: " "unprognostic (2.24e-1)" "potential prognostic favorable (5.99e-5)" "unprognostic (2.94e-1)" "unprognostic (2.27e-1)" "unprognostic (1.47e-2)" "unprognostic (1.44e-3)" "unprognostic (2.17e-2)" "unprognostic (2.33e-2)" "unprognostic (4.12e-3)" "unprognostic (3.55e-2)" "potential prognostic favorable (5.37e-4)" "unprognostic (1.19e-1)" "unprognostic (2.64e-3)" "unprognostic (1.97e-2)" "unprognostic (1.46e-1)" "unprognostic (9.29e-2)" "unprognostic (4.94e-1)" "unprognostic (9.71e-2)" "potential prognostic unfavorable (2.06e-4)" "unprognostic (2.23e-2)" "unprognostic (1.25e-3)" "unprognostic (3.33e-1)" "unprognostic (1.70e-2)" "potential prognostic unfavorable (7.52e-4)" "unprognostic (3.67e-1)" "unprognostic (1.65e-1)" "potential prognostic favorable (1.91e-4)" "unprognostic (1.11e-1)" PIGS ENSG00000087111 "Phosphatidylinositol glycan anchor biosynthesis class S" Q96S52 17 28553383-28571794 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 17.2;Bergmann glia: 17.4;Brain excitatory neurons: 16.1;Brain inhibitory neurons: 16.3;Choroid plexus epithelial cells: 13.9;Microglia: 14.7;Oligodendrocyte progenitor cells: 17.4;Oligodendrocytes: 16.3;Other brain neurons: 17.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018149 Approved NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 27: Breast cancer - Unknown function" "Cluster 22: Non-specific - Basic cellular functions" 23 "HPA018149: " "unprognostic (8.42e-3)" "unprognostic (5.33e-2)" "unprognostic (3.80e-2)" "unprognostic (1.71e-2)" "unprognostic (1.87e-1)" "unprognostic (8.63e-2)" "unprognostic (2.35e-1)" "unprognostic (9.44e-2)" "unprognostic (7.62e-2)" "unprognostic (3.57e-2)" "potential prognostic favorable (8.25e-5)" "unprognostic (1.04e-1)" "unprognostic (9.51e-2)" "unprognostic (3.14e-3)" "unprognostic (5.26e-2)" "unprognostic (1.19e-1)" "unprognostic (1.10e-2)" "unprognostic (6.52e-2)" "unprognostic (1.58e-2)" "unprognostic (1.23e-3)" "unprognostic (8.81e-2)" "unprognostic (4.91e-1)" "unprognostic (1.57e-1)" "unprognostic (1.41e-1)" "unprognostic (1.23e-2)" "unprognostic (1.28e-1)" "unprognostic (1.81e-1)" "unprognostic (2.56e-1)" "unprognostic (2.11e-1)" "unprognostic (2.60e-2)" "unprognostic (2.94e-2)" PIGT ENSG00000124155 "Phosphatidylinositol glycan anchor biosynthesis class T" Q969N2 20 45416084-45456934 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 202.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Fibroblasts, Colon - Macrophages, Skin - Fibroblasts_1, Skin - Fibroblasts_2, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" Other NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 27: Non-specific - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 108: Fibroblasts - ECM organization" 99 "unprognostic (1.90e-1)" "unprognostic (3.08e-2)" "unprognostic (1.82e-1)" "unprognostic (7.10e-3)" "unprognostic (4.68e-2)" "unprognostic (2.12e-1)" "unprognostic (1.45e-2)" "unprognostic (1.40e-3)" "unprognostic (1.68e-1)" "unprognostic (2.76e-1)" "unprognostic (1.13e-2)" "potential prognostic unfavorable (2.89e-5)" "unprognostic (9.02e-2)" "unprognostic (4.31e-3)" "unprognostic (3.77e-3)" "unprognostic (8.02e-2)" "unprognostic (2.80e-1)" "unprognostic (4.72e-2)" "unprognostic (9.52e-2)" "unprognostic (3.56e-1)" "unprognostic (2.07e-1)" "potential prognostic favorable (9.58e-4)" "unprognostic (2.82e-2)" "unprognostic (9.30e-2)" "unprognostic (1.68e-1)" "unprognostic (1.88e-1)" "unprognostic (1.06e-1)" "unprognostic (3.30e-2)" "unprognostic (1.15e-1)" "unprognostic (1.79e-2)" "unprognostic (1.11e-1)" PIGU "bA346K17.2, CDC91L1, GAB1" ENSG00000101464 "Phosphatidylinositol glycan anchor biosynthesis class U" Q9H490 20 34560542-34698790 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041706, HPA046766" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 73: Brain - Neuronal signaling" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 7: Non-specific - Transcription" 6 Nucleoplasm Cytosol "HPA041706: , HPA046766: " "unprognostic (3.04e-1)" "potential prognostic unfavorable (1.58e-4)" "unprognostic (3.03e-1)" "unprognostic (1.71e-1)" "unprognostic (1.47e-1)" "unprognostic (7.54e-2)" "unprognostic (1.45e-1)" "unprognostic (1.10e-1)" "unprognostic (3.18e-1)" "unprognostic (8.62e-2)" "unprognostic (4.96e-3)" "unprognostic (4.69e-2)" "unprognostic (1.34e-2)" "validated prognostic unfavorable (2.71e-8)" "validated prognostic unfavorable (3.51e-6)" "unprognostic (6.51e-2)" "unprognostic (3.15e-2)" "unprognostic (6.77e-2)" "unprognostic (2.83e-1)" "unprognostic (2.68e-2)" "unprognostic (1.89e-1)" "unprognostic (1.48e-1)" "unprognostic (2.40e-2)" "unprognostic (8.24e-2)" "unprognostic (3.66e-2)" "unprognostic (1.59e-2)" "unprognostic (1.09e-1)" "unprognostic (9.15e-2)" "unprognostic (2.20e-1)" "unprognostic (1.77e-1)" "unprognostic (2.11e-1)" PIGV FLJ20477 ENSG00000060642 "Phosphatidylinositol glycan anchor biosynthesis class V" Q9NUD9 1 26787054-26800659 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Glycosyltransferase, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 47.6;Late primary spermatocytes: 126.7;Late spermatids: 169.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054181 Approved "Endoplasmic reticulum,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 22: Epididymis - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 37: Non-specific - mRNA processing" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 3 Cytosol "Endoplasmic reticulum" "HPA054181: " "unprognostic (6.66e-2)" "unprognostic (1.68e-1)" "unprognostic (1.62e-1)" "potential prognostic unfavorable (2.36e-4)" "unprognostic (7.12e-2)" "unprognostic (1.67e-1)" "unprognostic (1.12e-2)" "unprognostic (1.45e-1)" "unprognostic (1.89e-1)" "unprognostic (6.38e-2)" "validated prognostic favorable (1.55e-12)" "validated prognostic favorable (4.59e-5)" "unprognostic (4.74e-2)" "unprognostic (3.03e-1)" "unprognostic (1.45e-1)" "unprognostic (4.64e-1)" "unprognostic (2.23e-2)" "unprognostic (4.99e-2)" "unprognostic (1.11e-2)" "unprognostic (8.72e-2)" "unprognostic (1.61e-1)" "unprognostic (1.15e-2)" "unprognostic (3.47e-2)" "unprognostic (4.63e-2)" "unprognostic (2.15e-2)" "unprognostic (2.43e-1)" "unprognostic (7.28e-2)" "unprognostic (2.14e-1)" "unprognostic (2.58e-1)" "unprognostic (6.55e-2)" "unprognostic (1.20e-1)" PIGW "FLJ37433, Gwt1" ENSG00000277161 "Phosphatidylinositol glycan anchor biosynthesis class W" Q7Z7B1 17 36534987-36539310 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Acyltransferase, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 2.1;Bergmann glia: 2.8;Brain excitatory neurons: 2.8;Brain inhibitory neurons: 3.2;Choroid plexus epithelial cells: 2.3;Distal convoluted tubule cells: 2.0;Ependymal cells: 3.3;Loop of henle epithelial cells: 2.0;Microglia: 2.4;Oligodendrocyte progenitor cells: 3.3;Oligodendrocytes: 3.4;Other brain neurons: 4.3;Papillary tip epithelial cells: 2.2;Renal collecting duct intercalated cells: 2.2;Renal collecting duct principal cells: 2.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023499 Approved "Plasma membrane" No Yes "Cluster 5: Non-specific - Cell proliferation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" "Plasma membrane" "HPA023499: " "unprognostic (1.00e-1)" "unprognostic (1.22e-2)" "unprognostic (2.75e-1)" "unprognostic (3.30e-1)" "unprognostic (1.20e-1)" "unprognostic (8.54e-2)" "unprognostic (1.37e-2)" "unprognostic (8.69e-2)" "unprognostic (4.06e-2)" "potential prognostic favorable (6.47e-4)" "unprognostic (1.17e-1)" "unprognostic (1.05e-1)" "unprognostic (2.75e-2)" "potential prognostic unfavorable (1.21e-4)" "unprognostic (9.51e-2)" "unprognostic (2.91e-2)" "unprognostic (2.79e-2)" "potential prognostic favorable (5.33e-4)" "unprognostic (2.85e-1)" "unprognostic (1.00e-1)" "unprognostic (2.97e-1)" "unprognostic (2.85e-3)" "unprognostic (1.09e-2)" "unprognostic (2.66e-1)" "unprognostic (9.56e-2)" "unprognostic (5.17e-2)" "unprognostic (1.58e-3)" "unprognostic (1.08e-1)" PIGX FLJ20522 ENSG00000163964 "Phosphatidylinositol glycan anchor biosynthesis class X" Q8TBF5 3 196639775-196736007 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 87.8" "Lineage enriched" "Detected in all" 8 "granulocytes: 87.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029409, HPA073301" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA029409: , HPA073301: " "unprognostic (2.77e-1)" "unprognostic (4.81e-2)" "unprognostic (3.86e-1)" "unprognostic (5.09e-2)" "unprognostic (2.17e-1)" "unprognostic (6.90e-3)" "unprognostic (3.61e-2)" "unprognostic (7.34e-3)" "unprognostic (2.27e-1)" "potential prognostic unfavorable (1.83e-5)" "unprognostic (9.48e-3)" "unprognostic (4.29e-2)" "unprognostic (1.76e-2)" "validated prognostic unfavorable (5.88e-5)" "validated prognostic unfavorable (3.43e-4)" "unprognostic (2.46e-2)" "unprognostic (1.73e-2)" "unprognostic (3.49e-2)" "unprognostic (3.01e-2)" "unprognostic (1.48e-1)" "unprognostic (1.92e-1)" "unprognostic (5.21e-2)" "unprognostic (4.12e-2)" "unprognostic (1.26e-1)" "unprognostic (3.68e-2)" "unprognostic (3.59e-1)" "unprognostic (5.75e-2)" "unprognostic (3.70e-2)" "unprognostic (2.86e-1)" "unprognostic (5.09e-2)" "unprognostic (5.74e-2)" PIGY MGC14156 ENSG00000255072 "Phosphatidylinositol glycan anchor biosynthesis class Y" Q3MUY2 4 88520998-88523776 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059018 Uncertain NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 76: Non-specific - Metabolism" "Cluster 27: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 102: Non-specific - Mixed function" 3 "HPA059018: " "unprognostic (9.06e-2)" "unprognostic (1.96e-1)" "unprognostic (2.52e-1)" "unprognostic (4.00e-1)" "unprognostic (7.29e-3)" "unprognostic (9.66e-3)" "unprognostic (2.74e-1)" "unprognostic (4.38e-2)" "unprognostic (8.71e-2)" "potential prognostic favorable (2.75e-6)" "unprognostic (2.47e-3)" "unprognostic (2.65e-2)" "unprognostic (1.44e-1)" "unprognostic (5.87e-2)" "unprognostic (1.52e-1)" "unprognostic (9.86e-2)" "unprognostic (9.57e-2)" "unprognostic (4.54e-2)" "unprognostic (2.10e-1)" "unprognostic (1.59e-1)" "unprognostic (1.42e-2)" "unprognostic (1.65e-1)" "unprognostic (5.92e-2)" "unprognostic (8.46e-2)" "unprognostic (1.22e-1)" "unprognostic (7.56e-2)" "unprognostic (3.36e-1)" "unprognostic (2.13e-2)" PIGZ "FLJ12768, MGC52163, SMP3" ENSG00000119227 "Phosphatidylinositol glycan anchor biosynthesis class Z" Q86VD9 3 196946356-196969060 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.2;intestine: 37.2" "Cell type enhanced" "Detected in many" "Colonocytes: 284.5;Enteric transient amplifying cells: 69.0;Enterocytes: 93.7;Goblet cells: 136.7;Prostatic hillock cells: 100.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes" "HPA058599, HPA059920" Approved NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 64: Non-specific - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" "HPA058599: , HPA059920: " "unprognostic (8.55e-3)" "unprognostic (1.63e-1)" "unprognostic (4.05e-2)" "unprognostic (2.19e-1)" "unprognostic (7.81e-2)" "potential prognostic favorable (6.74e-4)" "unprognostic (8.03e-2)" "unprognostic (1.68e-2)" "unprognostic (5.61e-2)" "potential prognostic unfavorable (1.52e-4)" "unprognostic (1.82e-1)" "unprognostic (1.33e-1)" "unprognostic (4.79e-3)" "unprognostic (9.18e-3)" "unprognostic (2.19e-1)" "unprognostic (1.39e-1)" "unprognostic (3.06e-1)" "unprognostic (5.66e-2)" "unprognostic (2.43e-1)" "unprognostic (2.12e-1)" "unprognostic (1.97e-1)" "unprognostic (2.54e-2)" "unprognostic (1.24e-1)" "unprognostic (1.69e-1)" "unprognostic (5.19e-2)" "unprognostic (1.94e-2)" "unprognostic (6.53e-2)" "unprognostic (2.35e-1)" "potential prognostic unfavorable (1.61e-4)" "unprognostic (1.44e-2)" PIH1D1 "DNAAF14, FLJ20643, MOT48, NOP17, Pih1" ENSG00000104872 "PIH1 domain containing 1" Q9NWS0 19 49446298-49453497 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 215.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047258 Approved Approved Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 4: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 111 Cytosol "HPA047258: " "unprognostic (1.34e-1)" "unprognostic (3.31e-1)" "unprognostic (2.27e-1)" "unprognostic (2.45e-1)" "unprognostic (1.49e-1)" "unprognostic (1.61e-1)" "unprognostic (5.54e-2)" "unprognostic (2.23e-1)" "unprognostic (2.11e-1)" "unprognostic (8.98e-2)" "unprognostic (1.27e-3)" "unprognostic (6.05e-2)" "unprognostic (1.95e-2)" "unprognostic (1.56e-3)" "potential prognostic unfavorable (1.50e-4)" "unprognostic (1.74e-3)" "unprognostic (9.67e-2)" "unprognostic (1.09e-1)" "unprognostic (1.62e-1)" "unprognostic (2.77e-1)" "unprognostic (1.36e-2)" "unprognostic (7.44e-2)" "unprognostic (2.62e-1)" "unprognostic (2.26e-2)" "unprognostic (3.23e-1)" "unprognostic (2.77e-1)" "unprognostic (1.33e-1)" "unprognostic (2.30e-1)" "unprognostic (9.10e-2)" "unprognostic (1.30e-1)" "unprognostic (3.94e-1)" PIH1D2 DNAAF15 ENSG00000150773 "PIH1 domain containing 2" Q8WWB5 11 112063218-112074274 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "testis: 62.1" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 67.0;Early spermatids: 371.4;Endometrial ciliated cells: 97.7;Ependymal cells: 102.3;Epididymal efferent duct ciliated cells: 85.2;Fallopian tube ciliated cells: 153.6;Late primary spermatocytes: 674.0;Late spermatids: 179.4;Respiratory ciliated cells: 176.7" "Group enriched" "Detected in many" 6 "choroid plexus epithelial cell: 42.2;ependymal cell: 116.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039496 Approved "Nucleoplasm,Vesicles,Basal body,Cytosol" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 64 Nucleoplasm "Vesicles, Basal body, Cytosol" "HPA039496: " "unprognostic (1.55e-2)" "unprognostic (2.38e-1)" "unprognostic (3.00e-1)" "unprognostic (4.71e-2)" "unprognostic (9.18e-2)" "unprognostic (6.86e-2)" "unprognostic (4.88e-2)" "potential prognostic favorable (1.84e-4)" "unprognostic (3.38e-3)" "potential prognostic favorable (1.04e-6)" "unprognostic (1.91e-3)" "unprognostic (1.64e-1)" "unprognostic (1.58e-1)" "unprognostic (2.81e-1)" "unprognostic (8.87e-2)" "unprognostic (2.87e-2)" "unprognostic (4.10e-1)" "unprognostic (4.78e-2)" "unprognostic (2.62e-2)" "unprognostic (4.39e-2)" "unprognostic (7.11e-2)" "unprognostic (2.17e-2)" "unprognostic (1.14e-1)" "unprognostic (4.69e-2)" "unprognostic (9.74e-3)" PIK3AP1 "BCAP, FLJ35564" ENSG00000155629 "Phosphoinositide-3-kinase adaptor protein 1" Q6ZUJ8 10 96593315-96720514 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 77.8;lymphoid tissue: 58.6;salivary gland: 69.4" "Cell type enhanced" "Detected in many" "B-cells: 201.3;Kupffer cells: 353.6;Lacrimal acinar cells: 154.9;Macrophages: 228.3;Microglia: 242.8;Monocyte progenitors: 154.6;monocytes: 481.9;Neutrophil progenitors: 347.0;Neutrophils: 962.8;NK-cells: 178.2;pDCs: 182.8;Salivary acinar cells: 174.3" "Group enriched" "Detected in many" 12 "central nervous system macrophage: 313.6;leukocyte: 148.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "intermediate monocyte: 44.6;memory B-cell: 48.4;naive B-cell: 44.6;non-classical monocyte: 123.7" "Group enriched" "Detected in all" 6 "B-cells: 48.4;monocytes: 123.7" "Cancer enhanced" "Detected in many" "Leukemia: 54.3;lymphoma: 97.4" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Lung - Neutrophils_2, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Ductal cells, Skeletal muscle - Macrophages, Spleen - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB026136, HPA038452" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" No No "Cluster 40: Monocytes - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 9 "Nucleoplasm, Cytosol" "Plasma membrane" "CAB026136: , HPA038452: " "unprognostic (6.24e-2)" "unprognostic (2.15e-1)" "unprognostic (3.45e-1)" "unprognostic (3.98e-3)" "unprognostic (2.04e-1)" "unprognostic (2.07e-1)" "unprognostic (1.30e-1)" "unprognostic (1.33e-1)" "unprognostic (3.22e-2)" "unprognostic (1.02e-1)" "unprognostic (3.56e-2)" "unprognostic (1.19e-1)" "unprognostic (1.51e-2)" "unprognostic (1.47e-1)" "unprognostic (3.36e-3)" "unprognostic (7.50e-2)" "unprognostic (1.16e-2)" "unprognostic (1.97e-1)" "unprognostic (1.95e-1)" "unprognostic (1.25e-1)" "unprognostic (1.76e-1)" "unprognostic (7.42e-2)" "unprognostic (9.52e-2)" "unprognostic (1.16e-1)" "unprognostic (5.70e-3)" "unprognostic (2.69e-2)" "unprognostic (3.15e-1)" "unprognostic (1.09e-1)" "unprognostic (1.01e-2)" "unprognostic (1.35e-1)" "unprognostic (4.42e-1)" PIK3C2A PI3K-C2alpha ENSG00000011405 "Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha" O00443 11 17077730-17207986 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Endocytosis, Exocytosis, Lipid metabolism" "Kinase, Transferase" "Cataract, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bergmann glia: 967.2;Sertoli cells: 550.5;Syncytiotrophoblasts: 729.7" "Cell type enhanced" "Detected in all" "Bergmann glia: 1081.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Skeletal muscle - Endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037641, HPA037642" Uncertain Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 54: Immune cells - T cell receptor" "Cluster 24: Non-specific - Unknown function" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 49 Nucleoplasm "Vesicles, Cytosol" "HPA037641: , HPA037642: " "unprognostic (9.45e-3)" "unprognostic (6.76e-2)" "unprognostic (1.81e-1)" "unprognostic (3.48e-2)" "unprognostic (1.09e-1)" "unprognostic (1.35e-2)" "unprognostic (1.02e-1)" "unprognostic (5.35e-3)" "unprognostic (1.40e-1)" "unprognostic (6.46e-3)" "validated prognostic favorable (3.04e-7)" "validated prognostic favorable (5.71e-4)" "unprognostic (1.25e-1)" "unprognostic (3.44e-2)" "unprognostic (9.75e-2)" "unprognostic (2.22e-1)" "unprognostic (2.00e-1)" "unprognostic (7.08e-2)" "unprognostic (3.37e-1)" "unprognostic (7.42e-2)" "potential prognostic unfavorable (4.53e-5)" "unprognostic (1.26e-2)" "potential prognostic unfavorable (6.06e-4)" "unprognostic (2.30e-1)" "unprognostic (4.45e-3)" "unprognostic (4.16e-1)" "unprognostic (5.70e-2)" "unprognostic (4.78e-2)" "unprognostic (2.24e-1)" "unprognostic (6.41e-2)" "unprognostic (3.25e-1)" PIK3C2B "C2-PI3K, PI3K-C2beta" ENSG00000133056 "Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta" O00750 1 204422628-204494805 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bergmann glia: 108.1;Foveolar cells: 97.8;Oligodendrocytes: 174.7;Urothelial cells: 87.0;Vascular endothelial cells: 114.3" "Cell type enhanced" "Detected in all" "oligodendrocyte: 203.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.7" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030515, HPA050360" Approved Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 26 "Nucleoplasm, Nuclear membrane" Cytosol "HPA030515: , HPA050360: " "unprognostic (1.52e-2)" "unprognostic (2.97e-2)" "potential prognostic favorable (1.01e-4)" "unprognostic (1.10e-1)" "unprognostic (1.59e-1)" "unprognostic (3.09e-1)" "unprognostic (2.24e-1)" "unprognostic (4.56e-2)" "unprognostic (2.20e-3)" "unprognostic (2.42e-2)" "validated prognostic favorable (1.16e-6)" "validated prognostic favorable (1.26e-4)" "unprognostic (7.38e-2)" "unprognostic (1.48e-3)" "unprognostic (1.22e-1)" "unprognostic (1.08e-2)" "unprognostic (1.37e-1)" "unprognostic (2.49e-2)" "unprognostic (9.21e-2)" "unprognostic (4.15e-3)" "unprognostic (2.63e-3)" "unprognostic (2.97e-2)" "unprognostic (7.54e-2)" "unprognostic (2.12e-1)" "unprognostic (1.45e-1)" "unprognostic (1.28e-2)" "unprognostic (1.90e-2)" "unprognostic (6.07e-2)" "unprognostic (9.46e-2)" "unprognostic (1.09e-1)" "unprognostic (1.83e-1)" PIK3C2G ENSG00000139144 "Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma" O75747 12 18242961-18648416 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Chemotaxis, Lipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 15.7;stomach 1: 20.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 266.6;Distal convoluted tubule cells: 602.3;Epididymal principal cells: 255.0;Gastric chief cells: 910.8;Hepatocytes: 287.4;Mucous neck cells: 1152.1;Parietal cells: 500.3;Renal collecting duct intercalated cells: 255.3;Renal collecting duct principal cells: 476.5;Renal connecting tubule cells: 1206.6;Salivary acinar cells: 292.9" "Cell type enhanced" "Detected in many" "astrocyte: 25.4;ependymal cell: 35.8;upper-layer intratelencephalic: 29.8" "Cancer enhanced" "Detected in some" "Stomach Adenocarcinoma (TCGA): 5.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 6.2" "Kidney - Intercalated cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA077589 Approved "Plasma membrane,Centrosome" NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 97: Non-specific - Cellular respiration" "Plasma membrane" Centrosome "HPA077589: " "unprognostic (1.64e-1)" "unprognostic (5.02e-2)" "unprognostic (5.15e-2)" "unprognostic (9.30e-2)" "unprognostic (1.03e-1)" "unprognostic (8.69e-2)" "unprognostic (6.38e-3)" "potential prognostic unfavorable (7.22e-4)" "unprognostic (2.05e-2)" "unprognostic (1.01e-1)" "unprognostic (9.85e-2)" PIK3C3 "hVps34, Vps34" ENSG00000078142 "Phosphatidylinositol 3-kinase catalytic subunit type 3" Q8NEB9 18 41955234-42087830 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Autophagy, Cell cycle, Cell division, Lipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040718 Approved NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 31: Non-specific - Transcription" "Cluster 13: Non-specific - Mixed function" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 45 "HPA040718: " "unprognostic (6.90e-2)" "unprognostic (1.43e-2)" "unprognostic (1.60e-1)" "unprognostic (2.83e-2)" "unprognostic (7.79e-2)" "unprognostic (2.18e-1)" "unprognostic (1.56e-2)" "unprognostic (4.24e-3)" "unprognostic (1.13e-1)" "unprognostic (1.21e-2)" "validated prognostic favorable (2.08e-5)" "validated prognostic favorable (9.80e-4)" "unprognostic (4.92e-2)" "potential prognostic unfavorable (5.04e-4)" "unprognostic (3.11e-1)" "unprognostic (4.29e-1)" "unprognostic (1.08e-1)" "unprognostic (1.60e-1)" "unprognostic (1.24e-2)" "unprognostic (1.07e-1)" "unprognostic (3.95e-2)" "unprognostic (4.86e-2)" "unprognostic (1.84e-2)" "unprognostic (2.24e-2)" "unprognostic (6.55e-2)" "unprognostic (4.69e-2)" "unprognostic (1.74e-1)" "unprognostic (2.55e-2)" "unprognostic (3.83e-2)" "unprognostic (3.68e-1)" "unprognostic (1.28e-2)" PIK3CA PI3K ENSG00000121879 "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha" P42336 3 179148114-179240093 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Angiogenesis, Lipid metabolism, Phagocytosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 384.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009985, CAB017804" Approved Approved "Microtubules,Primary cilium,Mitochondria,Cytosol" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 61: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 45 "Primary cilium, Cytosol" "Microtubules, Mitochondria" "CAB017804: , HPA009985: " "unprognostic (2.75e-1)" "unprognostic (2.49e-2)" "unprognostic (9.47e-2)" "unprognostic (1.90e-1)" "unprognostic (3.80e-2)" "unprognostic (2.08e-2)" "unprognostic (2.58e-2)" "unprognostic (1.19e-2)" "unprognostic (2.17e-1)" "unprognostic (2.38e-2)" "potential prognostic favorable (2.60e-6)" "unprognostic (1.26e-3)" "unprognostic (3.71e-2)" "unprognostic (2.60e-2)" "unprognostic (3.56e-1)" "unprognostic (3.58e-3)" "potential prognostic unfavorable (4.92e-4)" "unprognostic (1.11e-1)" "unprognostic (3.37e-2)" "unprognostic (7.17e-2)" "unprognostic (1.95e-3)" "unprognostic (2.39e-3)" "unprognostic (7.49e-2)" "unprognostic (6.69e-2)" "unprognostic (5.37e-2)" "unprognostic (9.64e-2)" "unprognostic (4.05e-2)" "unprognostic (8.15e-2)" "unprognostic (2.79e-1)" "unprognostic (1.11e-1)" "unprognostic (1.03e-1)" PIK3CB PIK3C1 ENSG00000051382 "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta" P42338 3 138652698-138834928 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Autophagy, Cell adhesion, Endocytosis, Lipid metabolism" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 574.8;Neutrophils: 499.6;Platelets: 498.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB031938, HPA042288, HPA064207" Approved Supported Nucleoplasm,Nucleoli,Vesicles,Midbody Yes No "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 31: Non-specific - Transcription" "Cluster 49: HMC-1 - Innate immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 23 "Nucleoplasm, Nucleoli" "Vesicles, Midbody" "CAB031938: , HPA042288: , HPA064207: " "unprognostic (2.53e-1)" "unprognostic (5.78e-3)" "unprognostic (1.10e-1)" "unprognostic (4.76e-3)" "unprognostic (9.74e-2)" "unprognostic (9.96e-2)" "unprognostic (1.75e-1)" "unprognostic (1.45e-1)" "unprognostic (1.21e-1)" "unprognostic (1.80e-2)" "validated prognostic favorable (4.34e-7)" "validated prognostic favorable (8.48e-4)" "unprognostic (1.26e-1)" "unprognostic (1.26e-1)" "unprognostic (7.55e-2)" "unprognostic (2.22e-2)" "unprognostic (1.62e-2)" "unprognostic (4.33e-2)" "unprognostic (2.32e-2)" "unprognostic (1.82e-1)" "unprognostic (7.66e-2)" "potential prognostic unfavorable (1.64e-4)" "unprognostic (8.43e-3)" "unprognostic (3.11e-1)" "unprognostic (5.33e-3)" "unprognostic (1.22e-1)" "unprognostic (3.59e-1)" "unprognostic (1.53e-1)" "unprognostic (6.67e-2)" "unprognostic (7.90e-2)" "unprognostic (2.32e-1)" PIK3CD p110D ENSG00000171608 "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta" O00329 1 9629889-9729114 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Adaptive immunity, Chemotaxis, Differentiation, Immunity, Inflammatory response, Innate immunity, Lipid metabolism" "Kinase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 44.2;lymphoid tissue: 44.5" "Cell type enhanced" "Detected in many" "B-cells: 117.5;Hematopoietic stem cells: 112.1;Innate lymphoid cells: 124.8;Kupffer cells: 163.0;Microglia: 153.2;Monocyte progenitors: 191.4;Neutrophil progenitors: 340.8;Neutrophils: 828.0;NK-cells: 159.4;pDCs: 245.3;T-cells: 132.6" "Group enriched" "Detected in all" 5 "central nervous system macrophage: 185.3;leukocyte: 245.1;pericyte: 237.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Leukemia: 57.4;lymphoma: 54.3" "Adrenal gland - Macrophages, Breast - T-cells, Testis - Spermatogonia, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015420, HPA044953" Enhanced Approved "Vesicles,Microtubules,Cytokinetic bridge,Primary cilium,Primary cilium tip,Cytosol" Yes No "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 18: Non-specific - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 24: Neutrophils - Innate immunity signal integration" 11 Vesicles "Microtubules, Cytokinetic bridge, Primary cilium, Primary cilium tip, Cytosol" "CAB015420: , HPA044953: " "unprognostic (2.54e-1)" "unprognostic (1.72e-2)" "unprognostic (1.12e-2)" "unprognostic (8.58e-2)" "unprognostic (1.70e-1)" "unprognostic (8.43e-2)" "unprognostic (6.33e-2)" "unprognostic (7.70e-2)" "unprognostic (7.00e-2)" "unprognostic (1.43e-1)" "unprognostic (2.50e-1)" "unprognostic (1.30e-1)" "potential prognostic favorable (5.14e-5)" "unprognostic (2.86e-1)" "unprognostic (1.11e-1)" "unprognostic (1.63e-3)" "unprognostic (1.99e-2)" "unprognostic (8.44e-3)" "unprognostic (1.97e-1)" "unprognostic (7.88e-3)" "unprognostic (1.18e-1)" "unprognostic (5.07e-2)" "potential prognostic unfavorable (2.14e-4)" "unprognostic (4.25e-2)" "unprognostic (1.75e-1)" "unprognostic (3.37e-2)" "unprognostic (1.40e-2)" "unprognostic (1.43e-1)" "unprognostic (1.43e-1)" "unprognostic (1.86e-1)" "unprognostic (4.74e-1)" PIK3CG ENSG00000105851 "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma" P48736 7 106865278-106908980 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Angiogenesis, Chemotaxis, Endocytosis, Immunity, Inflammatory response, Lipid metabolism" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 41.2;lymphoid tissue: 18.4" "Cell type enhanced" "Detected in some" "B-cells: 66.2;Microglia: 72.4;Monocyte progenitors: 82.7;monocytes: 64.6;Neutrophil progenitors: 331.3;Neutrophils: 326.7;NK-cells: 66.8;pDCs: 112.3;Plasma cells: 146.5;Tuft cells: 564.9" "Group enriched" "Detected in some" 20 "central nervous system macrophage: 97.0;leukocyte: 90.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 14 "Leukemia: 18.8;lymphoma: 26.1;Myeloma: 22.5" "Adrenal gland - Macrophages, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA069976 Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 10 "Plasma membrane" Cytosol "HPA069976: " "unprognostic (2.79e-2)" "unprognostic (7.74e-2)" "unprognostic (8.79e-3)" "unprognostic (3.05e-1)" "unprognostic (4.81e-2)" "unprognostic (3.92e-1)" "unprognostic (8.55e-2)" "unprognostic (6.57e-2)" "unprognostic (1.51e-3)" "unprognostic (1.61e-2)" "unprognostic (6.55e-2)" "unprognostic (2.01e-1)" "potential prognostic favorable (9.44e-4)" "unprognostic (4.14e-2)" "unprognostic (7.30e-2)" "unprognostic (1.51e-1)" "unprognostic (1.06e-2)" "unprognostic (4.51e-2)" "unprognostic (1.75e-1)" "unprognostic (8.38e-3)" "unprognostic (5.03e-2)" "unprognostic (1.21e-1)" "unprognostic (3.05e-1)" "unprognostic (3.40e-1)" PIK3IP1 "HGFL, MGC17330, TrIP" ENSG00000100100 "Phosphoinositide-3-kinase interacting protein 1" Q96FE7 22 31281594-31292534 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 136.4;Hematopoietic stem cells: 116.9;Innate lymphoid cells: 224.3;Mast cells: 131.8;Neutrophils: 118.2;NK-cells: 166.3;Platelets: 122.7;T-cells: 229.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "naive CD4 T-cell: 500.6" "Lineage enriched" "Detected in all" 6 "T-cells: 500.6" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA Yes 7100000 "Cluster 39: T-cells - T-cell receptor" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 30: White matter - Myelination" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 9: T-cells - Adaptive immunity: Regulation" 7 "unprognostic (2.10e-3)" "unprognostic (1.62e-1)" "unprognostic (5.02e-1)" "unprognostic (7.50e-2)" "unprognostic (1.04e-1)" "unprognostic (6.65e-3)" "unprognostic (5.29e-2)" "unprognostic (1.61e-3)" "unprognostic (2.78e-3)" "unprognostic (4.05e-2)" "unprognostic (1.62e-3)" "potential prognostic favorable (7.47e-4)" "unprognostic (2.65e-2)" "unprognostic (4.76e-2)" "unprognostic (5.28e-2)" "unprognostic (3.94e-3)" "unprognostic (3.87e-2)" "unprognostic (8.53e-2)" "unprognostic (1.79e-1)" "unprognostic (1.18e-2)" "unprognostic (6.91e-2)" "unprognostic (6.89e-2)" "unprognostic (2.68e-2)" "unprognostic (1.13e-2)" "unprognostic (6.25e-2)" "unprognostic (6.30e-2)" "unprognostic (1.19e-1)" "unprognostic (1.96e-2)" "unprognostic (1.75e-1)" "unprognostic (1.55e-1)" "unprognostic (1.06e-1)" PIK3R1 "GRB1, p85, p85-ALPHA" ENSG00000145675 "Phosphoinositide-3-kinase regulatory subunit 1" P27986 5 68215740-68301821 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Host-virus interaction, Protein transport, Stress response, Transport" "GTPase activation" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "NK-cells: 628.4;Oligodendrocyte progenitor cells: 578.8;Schwann cells: 570.8;Thymic myoid cells: 775.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001216, CAB004268" Approved Approved Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 53: Neurons - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 190 Cytosol "CAB004268: , HPA001216: " "unprognostic (5.44e-3)" "unprognostic (4.41e-2)" "unprognostic (2.62e-1)" "unprognostic (7.67e-2)" "unprognostic (1.39e-1)" "unprognostic (2.04e-1)" "unprognostic (2.37e-1)" "unprognostic (3.12e-2)" "unprognostic (1.06e-2)" "unprognostic (7.24e-3)" "potential prognostic favorable (5.75e-6)" "unprognostic (2.46e-3)" "unprognostic (1.16e-1)" "unprognostic (7.80e-3)" "potential prognostic favorable (2.14e-4)" "potential prognostic favorable (2.08e-4)" "unprognostic (5.59e-2)" "unprognostic (1.59e-1)" "unprognostic (1.35e-1)" "unprognostic (2.26e-1)" "unprognostic (6.40e-3)" "unprognostic (8.92e-2)" "unprognostic (1.32e-1)" "unprognostic (3.27e-1)" "unprognostic (1.58e-1)" "unprognostic (6.19e-2)" "unprognostic (1.49e-1)" "unprognostic (3.76e-3)" "unprognostic (1.29e-1)" "unprognostic (8.97e-2)" "unprognostic (7.94e-2)" PIK3R2 "p85, P85B" ENSG00000105647 "Phosphoinositide-3-kinase regulatory subunit 2" O00459 19 18153163-18170532 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Protein transport, Stress response, Transport" "GTPase activation" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 16 "Astrocytes: 12.7;Bergmann glia: 10.7;Brain excitatory neurons: 13.7;Brain inhibitory neurons: 14.0;Choroid plexus epithelial cells: 11.4;Ependymal cells: 21.2;Microglia: 9.5;Oligodendrocyte progenitor cells: 18.4;Oligodendrocytes: 11.7;Other brain neurons: 11.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells, Kidney - Fibroblasts, Spleen - Fibroblasts_1, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069291 Approved Approved "Golgi apparatus" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 22: Non-specific - Basic cellular functions" 84 "Golgi apparatus" "HPA069291: " "unprognostic (2.04e-2)" "unprognostic (5.27e-2)" "unprognostic (4.04e-2)" "unprognostic (2.95e-1)" "unprognostic (4.27e-2)" "unprognostic (2.01e-1)" "unprognostic (2.12e-1)" "unprognostic (7.58e-3)" "unprognostic (2.07e-2)" "unprognostic (8.50e-2)" "potential prognostic favorable (2.27e-5)" "unprognostic (2.37e-1)" "unprognostic (2.12e-1)" "unprognostic (1.23e-3)" "unprognostic (5.10e-3)" "unprognostic (1.84e-1)" "unprognostic (6.45e-2)" "unprognostic (2.82e-1)" "unprognostic (2.09e-3)" "unprognostic (2.51e-1)" "unprognostic (9.41e-3)" "unprognostic (1.57e-1)" "unprognostic (2.99e-1)" "unprognostic (9.67e-2)" "unprognostic (5.62e-2)" "unprognostic (1.09e-2)" "unprognostic (1.16e-2)" "unprognostic (8.75e-2)" "unprognostic (1.18e-1)" "unprognostic (1.84e-1)" "unprognostic (2.47e-1)" PIK3R3 p55 ENSG00000117461 "Phosphoinositide-3-kinase regulatory subunit 3" Q92569 1 46040140-46133036 "Cancer-related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 71.8;Differentiating spermatogonia: 26.0;Early primary spermatocytes: 27.3;Kupffer cells: 28.7;Late spermatids: 26.9;Respiratory deuterosomal cells: 28.0;Respiratory secretory cells: 29.7;Salivary duct cells: 44.7;Undifferentiated spermatogonia: 26.6;Vascular endothelial cells: 69.3" "Cell type enhanced" "Detected in many" "endothelial cell: 32.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 5.8" "Group enriched" "Detected in many" 9 "granulocytes: 5.8;monocytes: 2.4;T-cells: 2.3" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast), Colon - Endothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005751 Approved Approved "Nucleoplasm,Cytosol,Connecting piece,Mid piece,Principal piece,End piece" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 67: Testis - Mixed function" "Cluster 35: Non-specific - DNA binding" "Cluster 27: Breast cancer - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 144 "Nucleoplasm, Cytosol" "Connecting piece, Mid piece, Principal piece, End piece" "HPA005751: " "unprognostic (3.03e-3)" "unprognostic (1.27e-1)" "unprognostic (1.24e-1)" "unprognostic (5.17e-2)" "unprognostic (9.71e-3)" "unprognostic (8.70e-2)" "unprognostic (1.17e-1)" "unprognostic (2.42e-3)" "unprognostic (2.12e-3)" "unprognostic (2.45e-1)" "validated prognostic favorable (6.78e-10)" "validated prognostic favorable (2.04e-4)" "unprognostic (2.74e-2)" "unprognostic (1.89e-2)" "unprognostic (4.83e-2)" "unprognostic (1.54e-2)" "unprognostic (2.56e-2)" "unprognostic (1.60e-1)" "unprognostic (2.60e-1)" "unprognostic (2.79e-1)" "unprognostic (9.69e-2)" "unprognostic (2.20e-2)" "unprognostic (1.62e-1)" "unprognostic (3.91e-1)" "unprognostic (2.96e-1)" "unprognostic (3.22e-1)" "unprognostic (2.37e-2)" "unprognostic (1.54e-1)" "unprognostic (2.75e-2)" "unprognostic (1.03e-1)" "unprognostic (5.96e-2)" PIK3R4 "p150, VPS15" ENSG00000196455 "Phosphoinositide-3-kinase regulatory subunit 4" Q99570 3 130678934-130746829 "Enzymes, Essential proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036032, HPA036033" Approved Approved "Vesicles,Microtubules,Cytokinetic bridge,Primary cilium,Basal body" Yes NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 47 "Vesicles, Microtubules, Primary cilium" "Cytokinetic bridge, Basal body" "HPA036032: , HPA036033: " "unprognostic (3.24e-1)" "unprognostic (3.24e-2)" "unprognostic (2.16e-1)" "unprognostic (6.57e-3)" "unprognostic (1.36e-1)" "unprognostic (1.83e-1)" "unprognostic (2.60e-1)" "unprognostic (2.11e-1)" "unprognostic (3.08e-2)" "unprognostic (1.68e-2)" "potential prognostic favorable (1.29e-7)" "unprognostic (2.64e-2)" "unprognostic (9.68e-2)" "unprognostic (1.57e-1)" "unprognostic (1.73e-1)" "unprognostic (2.79e-2)" "unprognostic (1.13e-1)" "unprognostic (2.62e-1)" "unprognostic (2.53e-1)" "unprognostic (1.67e-3)" "unprognostic (3.91e-1)" "unprognostic (1.63e-3)" "unprognostic (1.64e-2)" "unprognostic (1.51e-1)" "unprognostic (1.18e-2)" "unprognostic (8.88e-3)" "unprognostic (7.16e-2)" "unprognostic (1.46e-1)" "unprognostic (1.72e-1)" "unprognostic (8.77e-2)" "unprognostic (1.97e-1)" PIK3R5 "p101, P101-PI3K" ENSG00000141506 "Phosphoinositide-3-kinase regulatory subunit 5" Q8WYR1 17 8878911-8965712 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 84.2" "Cell type enhanced" "Detected in many" "cDC: 375.3;Kupffer cells: 320.8;Macrophages: 460.4;Microglia: 333.5;monocytes: 812.2;Neutrophil progenitors: 279.0;Neutrophils: 2074.7;NK-cells: 383.0;pDCs: 357.6;T-cells: 266.1" "Group enriched" "Detected in some" 96 "central nervous system macrophage: 431.0;leukocyte: 339.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Leukemia: 11.8;lymphoma: 6.1" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Skeletal muscle - Macrophages, Spleen - Neutrophils_2, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA044505, HPA052247, HPA052412" Uncertain Supported "Centriolar satellite,Cytosol" No NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 15: Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 59: Leukemia - T-cell receptor" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 1 Cytosol "Centriolar satellite" "HPA044505: , HPA052247: , HPA052412: " "unprognostic (3.90e-1)" "unprognostic (9.69e-2)" "unprognostic (3.44e-3)" "unprognostic (6.89e-3)" "unprognostic (1.78e-1)" "unprognostic (5.64e-2)" "unprognostic (1.54e-1)" "unprognostic (2.37e-1)" "unprognostic (8.40e-3)" "unprognostic (5.35e-2)" "unprognostic (1.79e-2)" "unprognostic (4.60e-1)" "unprognostic (1.15e-2)" "unprognostic (1.17e-2)" "unprognostic (1.02e-2)" "unprognostic (1.17e-1)" "unprognostic (5.57e-2)" "unprognostic (1.33e-1)" "unprognostic (2.79e-2)" "unprognostic (1.96e-1)" "unprognostic (1.26e-1)" "unprognostic (7.76e-2)" "unprognostic (1.17e-1)" "unprognostic (1.20e-2)" "unprognostic (1.66e-3)" "unprognostic (1.03e-1)" "unprognostic (3.47e-2)" "unprognostic (1.55e-2)" "unprognostic (6.14e-2)" "unprognostic (1.07e-1)" PIK3R6 "C17orf38, FLJ34500, HsT41028, p87PIKAP" ENSG00000276231 "Phosphoinositide-3-kinase regulatory subunit 6" Q5UE93 17 8802722-8867677 "Predicted intracellular proteins" Angiogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 4.5" "Cell type enhanced" "Detected in some" "cDC: 21.5;Early spermatids: 20.9;Hematopoietic stem cells: 18.9;Hofbauer cells: 24.7;Late spermatids: 37.0;Macrophages: 24.4;Mast cells: 112.9;Megakaryocyte progenitors: 22.9;Microglia: 45.0;monocytes: 22.3;Neutrophil progenitors: 20.9;Neutrophils: 40.7;Thymocytes: 27.9" "Group enriched" "Detected in some" 5 "central nervous system macrophage: 51.3;pericyte: 66.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "basophil: 22.0;eosinophil: 75.9" "Lineage enriched" "Detected in many" 7 "granulocytes: 75.9" "Group enriched" "Detected in some" 6 "Leukemia: 7.3;lymphoma: 5.9" "Adrenal gland - Macrophages, Colon - Mast cells, Skeletal muscle - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA023077 Approved Approved "Nucleoplasm,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 58: Mast cells - Allergic inflammatory responses" 3 "Nucleoplasm, Golgi apparatus" "Plasma membrane, Cytosol" "HPA023077: " "unprognostic (7.54e-3)" "unprognostic (6.27e-3)" "unprognostic (1.26e-1)" "unprognostic (1.10e-1)" "unprognostic (9.01e-3)" "unprognostic (1.83e-1)" "unprognostic (6.39e-2)" "unprognostic (2.02e-1)" "unprognostic (7.88e-3)" "potential prognostic unfavorable (6.60e-4)" "unprognostic (1.26e-1)" "unprognostic (5.48e-2)" "unprognostic (1.29e-1)" "unprognostic (4.15e-1)" "unprognostic (1.91e-2)" PIKFYVE "FAB1, KIAA0981, MGC40423, p235, PIP5K, PIP5K3, ZFYVE29" ENSG00000115020 "Phosphoinositide kinase, FYVE-type zinc finger containing" Q9Y2I7 2 208266255-208358746 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction, Lipid metabolism" "Kinase, Transferase" "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 348.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042604 Uncertain NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 59: Leukemia - T-cell receptor" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 12 "HPA042604: " "unprognostic (2.17e-2)" "unprognostic (4.28e-2)" "unprognostic (1.35e-1)" "unprognostic (5.60e-2)" "unprognostic (9.34e-2)" "unprognostic (1.36e-1)" "unprognostic (2.07e-2)" "unprognostic (8.02e-2)" "potential prognostic favorable (9.29e-4)" "unprognostic (2.81e-1)" "potential prognostic favorable (1.03e-4)" "unprognostic (9.31e-3)" "unprognostic (2.61e-1)" "unprognostic (6.76e-3)" "unprognostic (4.69e-2)" "unprognostic (9.27e-2)" "unprognostic (1.09e-1)" "unprognostic (1.24e-2)" "unprognostic (1.25e-1)" "unprognostic (3.89e-2)" "unprognostic (8.18e-2)" "unprognostic (1.76e-1)" "unprognostic (1.31e-3)" "unprognostic (4.52e-2)" "unprognostic (1.15e-1)" "unprognostic (4.70e-3)" "unprognostic (3.15e-2)" "unprognostic (2.42e-1)" "unprognostic (2.36e-1)" "unprognostic (6.71e-2)" "unprognostic (2.48e-1)" PILRA FDF03 ENSG00000085514 "Paired immunoglobin like type 2 receptor alpha" Q9UKJ1 7 100367530-100400096 "Predicted membrane proteins, Predicted secreted proteins" "Host-virus interaction" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "Neutrophils: 1383.0" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 204.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 1664.4;non-classical monocyte: 1150.6" "Group enriched" "Detected in all" 5 "granulocytes: 1664.4;monocytes: 1150.6" "Cancer enhanced" "Detected in some" "Leukemia: 6.8" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages" HPA056132 Approved "Secreted to blood" Receptor NA NA 890000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 5: Spleen - Immune response" "Cluster 25: Non-specific - Transcription" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 4 "HPA056132: " "unprognostic (2.66e-2)" "unprognostic (2.03e-1)" "unprognostic (4.99e-2)" "unprognostic (1.84e-2)" "unprognostic (2.10e-1)" "unprognostic (1.53e-1)" "unprognostic (5.62e-2)" "unprognostic (1.13e-1)" "unprognostic (2.20e-1)" "unprognostic (2.02e-1)" "unprognostic (4.29e-2)" "unprognostic (3.17e-1)" "unprognostic (1.81e-1)" "unprognostic (7.75e-2)" "unprognostic (6.17e-2)" "unprognostic (1.13e-1)" "unprognostic (9.92e-3)" "unprognostic (2.19e-1)" "unprognostic (2.47e-1)" "unprognostic (7.38e-2)" "unprognostic (2.97e-1)" "unprognostic (4.48e-2)" "unprognostic (7.81e-2)" "unprognostic (6.33e-2)" "unprognostic (4.61e-2)" "unprognostic (9.89e-2)" "unprognostic (1.95e-3)" "unprognostic (5.81e-3)" "unprognostic (9.50e-3)" "unprognostic (1.63e-1)" "unprognostic (1.50e-1)" PILRB "FDFACT1, FDFACT2" ENSG00000121716 "Paired immunoglobin like type 2 receptor beta" Q9UKJ0 7 100352176-100367831 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 57.6;Bergmann glia: 31.5;Brain excitatory neurons: 54.1;Brain inhibitory neurons: 50.0;Choroid plexus epithelial cells: 79.6;Distal convoluted tubule cells: 71.1;Ependymal cells: 40.0;Loop of henle epithelial cells: 68.2;Microglia: 39.3;Oligodendrocyte progenitor cells: 29.7;Oligodendrocytes: 32.0;Other brain neurons: 35.9;Papillary tip epithelial cells: 35.7;Podocytes: 47.0;Proximal tubule cells: 85.7;Renal collecting duct intercalated cells: 56.0;Renal collecting duct principal cells: 44.7;Renal connecting tubule cells: 59.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 251.7" "Group enriched" "Detected in all" 8 "granulocytes: 251.7;monocytes: 76.0" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" HPA026750 Approved Approved Mitochondria "Intracellular and membrane" Receptor NA Yes "Cluster 7: Non-specific - Innate immune response" "Cluster 67: Testis - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 102: Non-specific - Mixed function" 28 Mitochondria "HPA026750: " "unprognostic (2.05e-3)" "unprognostic (1.00e-3)" "unprognostic (8.15e-2)" "unprognostic (1.28e-1)" "unprognostic (3.87e-2)" "unprognostic (3.43e-2)" "unprognostic (1.08e-1)" "unprognostic (2.96e-1)" "unprognostic (1.34e-2)" "unprognostic (2.51e-3)" "potential prognostic unfavorable (6.45e-5)" "unprognostic (1.28e-1)" "unprognostic (1.82e-2)" "unprognostic (6.45e-2)" "unprognostic (2.38e-2)" "unprognostic (1.11e-1)" "unprognostic (2.97e-1)" "unprognostic (1.57e-2)" "unprognostic (3.02e-3)" "unprognostic (1.49e-1)" "unprognostic (1.26e-3)" "unprognostic (1.62e-3)" "unprognostic (1.04e-3)" "unprognostic (5.23e-2)" "unprognostic (6.11e-2)" "unprognostic (1.47e-1)" "unprognostic (4.70e-2)" "unprognostic (5.86e-2)" "unprognostic (2.85e-1)" "unprognostic (1.16e-1)" "unprognostic (1.10e-1)" PIM1 PIM ENSG00000137193 "Pim-1 proto-oncogene, serine/threonine kinase" P11309 6 37170152-37175428 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Host-virus interaction" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 206.5" "Cell type enriched" "Detected in many" 4 "Esophageal apical cells: 1769.1" "Cell type enriched" "Detected in many" 4 "leukocyte: 77.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 322.5" "Lineage enriched" "Detected in all" 4 "granulocytes: 322.5" "Cancer enhanced" "Detected in all" "Leukemia: 201.7" "Colon - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003941, CAB017040" Uncertain Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 84: Apical squamous epithelium - Cornification" 25 Cytosol "Nucleoplasm, Nucleoli" "CAB017040: , HPA003941: " "unprognostic (2.11e-1)" "unprognostic (1.04e-2)" "unprognostic (4.87e-2)" "unprognostic (1.99e-1)" "unprognostic (6.86e-2)" "unprognostic (3.18e-2)" "unprognostic (4.18e-3)" "unprognostic (2.41e-1)" "unprognostic (9.31e-2)" "unprognostic (2.89e-1)" "unprognostic (1.38e-3)" "unprognostic (2.94e-2)" "unprognostic (2.53e-2)" "unprognostic (3.09e-1)" "unprognostic (1.63e-2)" "unprognostic (1.60e-1)" "unprognostic (3.36e-3)" "unprognostic (1.08e-1)" "unprognostic (6.26e-3)" "unprognostic (8.75e-2)" "unprognostic (1.99e-2)" "unprognostic (2.74e-2)" "unprognostic (2.07e-1)" "unprognostic (1.21e-1)" "unprognostic (7.29e-2)" "unprognostic (1.08e-2)" "unprognostic (3.91e-1)" "unprognostic (1.53e-2)" "unprognostic (1.57e-1)" "potential prognostic unfavorable (2.14e-4)" "unprognostic (1.21e-2)" PIM2 ENSG00000102096 "Pim-2 proto-oncogene, serine/threonine kinase" Q9P1W9 X 48913182-48919024 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 96.5;intestine: 82.3;lymphoid tissue: 152.7" "Cell type enriched" "Detected in many" 5 "Plasma cells: 420.8" "Cell type enhanced" "Detected in many" "leukocyte: 16.1" "Cancer enriched" "Detected in all" 7 "Testicular Germ Cell Tumor (TCGA): 384.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in all" 4 "Myeloma: 827.3" "Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Stomach - Plasma cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000285 Approved Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 29: Forebrain - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 67: Plasma cells - Plasma cell differentiation" 5 Cytosol "HPA000285: " "unprognostic (1.59e-3)" "unprognostic (3.50e-3)" "unprognostic (2.98e-1)" "unprognostic (2.72e-2)" "unprognostic (1.05e-1)" "unprognostic (2.60e-1)" "unprognostic (1.91e-3)" "unprognostic (1.02e-2)" "unprognostic (3.29e-3)" "unprognostic (4.43e-3)" "potential prognostic unfavorable (1.51e-5)" "unprognostic (7.69e-2)" "potential prognostic unfavorable (1.69e-4)" "unprognostic (9.32e-2)" "unprognostic (5.17e-2)" "unprognostic (1.30e-2)" "unprognostic (3.65e-2)" "unprognostic (4.92e-2)" "unprognostic (1.43e-1)" "unprognostic (1.01e-1)" "unprognostic (5.00e-3)" "unprognostic (2.06e-2)" "unprognostic (1.96e-1)" "unprognostic (7.94e-2)" "unprognostic (7.53e-2)" "unprognostic (1.10e-2)" "unprognostic (1.53e-2)" "unprognostic (2.23e-1)" "unprognostic (2.45e-1)" "unprognostic (5.24e-2)" "unprognostic (1.18e-1)" PIM3 ENSG00000198355 "Pim-3 proto-oncogene, serine/threonine kinase" Q86V86 22 49960768-49964072 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 317.7;Extravillous trophoblasts: 461.2;Prostatic club cells: 352.4;Syncytiotrophoblasts: 458.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 20.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068758 Supported Cytosol NA Yes "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 24: Non-specific - Transcription" "Cluster 18: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 1 Cytosol "HPA068758: " "unprognostic (1.06e-1)" "unprognostic (7.39e-2)" "unprognostic (8.11e-2)" "unprognostic (1.51e-2)" "unprognostic (3.29e-2)" "unprognostic (4.78e-2)" "unprognostic (1.56e-2)" "unprognostic (5.80e-2)" "unprognostic (9.04e-2)" "unprognostic (3.06e-2)" "unprognostic (3.78e-1)" "unprognostic (5.62e-2)" "unprognostic (3.05e-2)" "unprognostic (1.75e-2)" "unprognostic (2.28e-1)" "unprognostic (9.93e-3)" "unprognostic (1.89e-1)" "unprognostic (2.03e-1)" "unprognostic (3.07e-2)" "potential prognostic unfavorable (5.70e-4)" "unprognostic (8.65e-2)" "unprognostic (2.33e-2)" "unprognostic (1.03e-2)" "unprognostic (3.15e-1)" "unprognostic (4.24e-2)" "unprognostic (2.24e-2)" "unprognostic (4.54e-2)" "unprognostic (3.51e-2)" "unprognostic (1.85e-1)" "potential prognostic unfavorable (1.09e-4)" "unprognostic (5.39e-2)" PIMREG "CATS, FAM64A, FLJ10156, FLJ10491, RCS1" ENSG00000129195 "PICALM interacting mitotic regulator" Q9BSJ6 17 6444441-6451469 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 13.0" "Cell type enhanced" "Detected in some" "Enteric stem cells: 6.0;Enteric transient amplifying cells: 18.9;Epicardial cells: 6.8;Esophageal basal cells: 9.9;Gastric progenitor cells: 15.4;Granulosa cells: 12.2;Hofbauer cells: 15.2;Megakaryocyte progenitors: 12.8;Megakaryocytes: 6.2;Monocyte progenitors: 21.6;Neuroendocrine cells: 6.2;Paneth cells: 11.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "NK-cell: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Thyroid gland - Mitotic cells (Thyroid)" "Region enhanced" "Detected in many" "white matter: 5.7" "Low region specificity" "Detected in some" "HPA043783, HPA049934" Uncertain Enhanced Nucleoplasm Yes Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 2: Neurons - Nucleosome" "Cluster 24: Non-specific - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 20 Nucleoplasm "HPA043783: , HPA049934: " "unprognostic (8.36e-2)" "unprognostic (2.88e-2)" "unprognostic (7.76e-2)" "unprognostic (2.40e-1)" "unprognostic (4.39e-2)" "unprognostic (1.59e-1)" "unprognostic (2.97e-2)" "unprognostic (7.13e-2)" "potential prognostic unfavorable (4.30e-6)" "validated prognostic unfavorable (1.57e-9)" "validated prognostic unfavorable (1.73e-4)" "potential prognostic unfavorable (6.70e-6)" "unprognostic (2.62e-2)" "potential prognostic unfavorable (7.49e-5)" "unprognostic (4.11e-3)" "unprognostic (3.46e-2)" "unprognostic (3.87e-2)" "unprognostic (3.47e-2)" "unprognostic (1.72e-1)" "unprognostic (2.55e-3)" "unprognostic (4.63e-2)" "unprognostic (6.91e-2)" "unprognostic (1.88e-1)" "unprognostic (6.06e-2)" "unprognostic (1.38e-1)" "unprognostic (1.32e-1)" "unprognostic (2.93e-1)" "unprognostic (8.64e-2)" PIN1 dod ENSG00000127445 "Peptidylprolyl cis/trans isomerase, NIMA-interacting 1" Q13526 19 9835257-9849689 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle" "Isomerase, Rotamase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 256.4" "Cell type enhanced" "Detected in many" "Early spermatids: 277.3;Late primary spermatocytes: 338.6;Late spermatids: 1255.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004528, CAB009326, HPA068650, HPA070887" Enhanced Supported Nucleoplasm,Cytosol NA NA 83000 "Cluster 29: Non-specific - Unknown function" "Cluster 78: Brain - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 23: Non-specific - Transcription" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 193 Nucleoplasm Cytosol "CAB004528: , CAB009326: , HPA068650: , HPA070887: " "unprognostic (4.83e-2)" "unprognostic (3.38e-1)" "unprognostic (2.01e-1)" "unprognostic (4.99e-2)" "unprognostic (1.57e-1)" "unprognostic (9.87e-3)" "unprognostic (3.45e-1)" "unprognostic (5.33e-2)" "unprognostic (7.85e-3)" "unprognostic (6.58e-2)" "potential prognostic favorable (1.06e-5)" "unprognostic (4.50e-2)" "potential prognostic favorable (2.19e-4)" "unprognostic (2.01e-1)" "unprognostic (5.02e-3)" "unprognostic (3.05e-1)" "unprognostic (4.19e-2)" "unprognostic (6.56e-2)" "unprognostic (2.55e-1)" "potential prognostic favorable (9.12e-4)" "unprognostic (2.04e-1)" "unprognostic (3.27e-3)" "unprognostic (1.42e-1)" "unprognostic (4.29e-1)" "unprognostic (1.24e-1)" "unprognostic (8.40e-3)" "unprognostic (1.27e-1)" "unprognostic (1.12e-1)" "unprognostic (1.52e-1)" "unprognostic (2.37e-1)" "unprognostic (2.02e-1)" PIN4 "EPVH, PAR14, PAR17" ENSG00000102309 "Peptidylprolyl cis/trans isomerase, NIMA-interacting 4" Q9Y237 X 72181353-72302926 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA-binding, Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 292.9;Mesothelial cells: 310.5;Thymocytes: 421.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054483, HPA064504" Approved Supported "Nucleoplasm,Nucleoli,Mitotic chromosome" Yes No "Cluster 42: Non-specific - Vesicular transport" "Cluster 76: Non-specific - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 44: Plasma cells - Antibody production & secretion" 13 "Nucleoplasm, Nucleoli" "Mitotic chromosome" "HPA054483: , HPA064504: " "unprognostic (2.62e-1)" "unprognostic (4.46e-2)" "unprognostic (2.39e-1)" "unprognostic (1.53e-2)" "unprognostic (9.33e-2)" "unprognostic (1.53e-1)" "unprognostic (6.52e-2)" "unprognostic (2.25e-1)" "potential prognostic unfavorable (2.64e-4)" "potential prognostic unfavorable (4.74e-4)" "unprognostic (8.09e-2)" "unprognostic (9.61e-2)" "unprognostic (7.86e-2)" "potential prognostic unfavorable (8.65e-4)" "unprognostic (2.58e-2)" "unprognostic (2.72e-1)" "unprognostic (1.57e-1)" "unprognostic (2.15e-3)" "unprognostic (1.75e-2)" "unprognostic (9.69e-3)" "unprognostic (2.79e-1)" "unprognostic (2.13e-1)" "unprognostic (2.03e-1)" "unprognostic (1.84e-1)" "unprognostic (3.26e-1)" "unprognostic (1.71e-1)" "unprognostic (1.21e-1)" "unprognostic (3.48e-1)" "unprognostic (7.73e-3)" "unprognostic (9.31e-2)" "unprognostic (1.62e-1)" PINK1 "BRPK, PARK6" ENSG00000158828 "PTEN induced kinase 1" Q9BXM7 1 20633458-20651511 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Autophagy "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 358.8;tongue: 366.6" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 207.9;Late primary spermatocytes: 179.0;Late spermatids: 244.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 8.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001931, CAB026191" Uncertain NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 195 "CAB026191: , HPA001931: " "unprognostic (5.02e-2)" "unprognostic (3.59e-3)" "unprognostic (1.02e-1)" "unprognostic (4.52e-2)" "unprognostic (5.54e-2)" "unprognostic (2.38e-1)" "unprognostic (6.01e-2)" "unprognostic (4.07e-2)" "potential prognostic unfavorable (8.98e-4)" "unprognostic (1.36e-1)" "validated prognostic favorable (2.55e-15)" "validated prognostic favorable (1.30e-4)" "potential prognostic favorable (7.90e-4)" "unprognostic (7.63e-2)" "unprognostic (3.17e-2)" "unprognostic (1.31e-1)" "unprognostic (1.22e-1)" "potential prognostic unfavorable (4.59e-4)" "unprognostic (2.14e-1)" "unprognostic (9.50e-3)" "unprognostic (3.57e-3)" "unprognostic (1.61e-1)" "unprognostic (5.68e-2)" "unprognostic (5.18e-2)" "unprognostic (7.18e-2)" "unprognostic (2.45e-1)" "unprognostic (9.96e-2)" "unprognostic (2.35e-1)" "unprognostic (3.82e-1)" "unprognostic (6.54e-2)" "unprognostic (3.85e-1)" PINLYP ENSG00000234465 "Phospholipase A2 inhibitor and LY6/PLAUR domain containing" A6NC86 19 43575801-43583964 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 33.2;Leydig cells: 26.9;Ovarian stromal cells: 27.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 21.1" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 20.8" "Skin - Outer root sheath cells, Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Not detected" "Not detected" HPA061218 Uncertain Approved "Vesicles,Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Centrosome,Basal body" "Secreted to blood" "No annotated function" Yes NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 64: Non-specific - Transcription" "Cluster 46: Brainstem - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 94: Gonadal somatic cells - Mixed function" "Vesicles, Microtubules, Primary cilium" "Cytokinetic bridge, Mitotic spindle, Centrosome, Basal body" "HPA061218: " "unprognostic (7.50e-2)" "unprognostic (1.06e-1)" "unprognostic (6.37e-2)" "unprognostic (3.43e-2)" "unprognostic (2.24e-1)" "unprognostic (1.86e-3)" "potential prognostic unfavorable (2.45e-6)" "unprognostic (5.67e-2)" "unprognostic (8.26e-2)" "unprognostic (2.55e-2)" "unprognostic (3.35e-2)" "unprognostic (7.19e-2)" "unprognostic (9.68e-2)" "potential prognostic favorable (6.89e-4)" "unprognostic (3.48e-3)" "unprognostic (5.56e-2)" "unprognostic (3.07e-2)" "unprognostic (1.65e-1)" "unprognostic (7.20e-2)" "unprognostic (1.06e-1)" "unprognostic (2.00e-1)" "unprognostic (1.29e-2)" "unprognostic (2.04e-1)" "unprognostic (2.36e-2)" "unprognostic (1.66e-1)" "unprognostic (3.47e-3)" "unprognostic (2.19e-1)" "unprognostic (2.48e-2)" "unprognostic (1.74e-1)" PINX1 "FLJ20565, Gno1, LPTL, LPTS, MGC8850, Pxr1" ENSG00000254093 "PIN2 (TERF1) interacting telomerase inhibitor 1" Q96BK5 8 10764961-10839884 "Predicted intracellular proteins" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 22.1;Late primary spermatocytes: 19.8;Late spermatids: 28.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023139, HPA023146" Uncertain Supported Nucleoplasm,Nucleoli,Mitochondria NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 15: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 43 Nucleoli "Nucleoplasm, Mitochondria" "HPA023139: , HPA023146: " "unprognostic (1.48e-1)" "unprognostic (3.01e-2)" "unprognostic (8.47e-2)" "unprognostic (1.93e-2)" "unprognostic (1.39e-1)" "unprognostic (3.40e-1)" "potential prognostic favorable (4.10e-4)" "unprognostic (4.47e-2)" "unprognostic (3.53e-2)" "potential prognostic favorable (1.49e-4)" "unprognostic (6.50e-3)" "unprognostic (1.86e-1)" "unprognostic (3.38e-2)" "unprognostic (6.17e-2)" "unprognostic (1.30e-1)" "unprognostic (3.19e-2)" "unprognostic (4.11e-1)" "unprognostic (8.65e-2)" "unprognostic (4.40e-2)" "unprognostic (9.85e-3)" "unprognostic (2.28e-1)" "unprognostic (3.38e-1)" "unprognostic (3.88e-2)" "unprognostic (1.51e-2)" "unprognostic (1.41e-2)" "unprognostic (3.68e-1)" "unprognostic (2.87e-1)" "unprognostic (1.12e-1)" "unprognostic (1.42e-1)" PINX1 "FLJ20565, Gno1, LPTL, LPTS, MGC8850, Pxr1" ENSG00000258724 "PIN2 (TERF1) interacting telomerase inhibitor 1" 8 10725399-10839847 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 1.6;vagina: 4.6" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 11.9;Brain inhibitory neurons: 13.8;Choroid plexus epithelial cells: 5.9;Oligodendrocyte progenitor cells: 3.8;Oligodendrocytes: 4.4;Other brain neurons: 9.7;Somatotrophs: 10.8;Thymic myoid cells: 15.0" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 2.0;Gallbladder cancer: 2.0" HPA009065 Uncertain Approved "Nuclear speckles,Golgi apparatus" NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 1: Neuronal - Visual perception" "Cluster 35: Neurons - Synaptic function & neurogenesis" 14 "Nuclear speckles" "Golgi apparatus" "HPA009065: " "unprognostic (6.54e-2)" "unprognostic (1.07e-1)" PIP "BRST-2, GCDFP-15, GCDFP15, GPIP4, SABP" ENSG00000159763 "Prolactin induced protein" P12273 7 143132077-143139739 "Plasma proteins, Predicted secreted proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "salivary gland: 17175.0" "Group enriched" "Detected in some" 7 "Lacrimal acinar cells: 23034.3;Salivary acinar cells: 5978.3" "Cell type enriched" "Detected in single" 5 "oligodendrocyte: 4.3" "Cancer enriched" "Detected in many" 24 "Breast Invasive Carcinoma (TCGA): 1346.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 161 "breast cancer: 113.7" "Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB002661, HPA009177" Enhanced "Secreted in other tissues" Other NA NA 18000000 "Cluster 82: Salivary gland - Secretion" "Cluster 30: White matter - Myelination" "Cluster 27: Breast cancer - Unknown function" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 6 "CAB002661: , HPA009177: " "unprognostic (5.01e-2)" "unprognostic (2.39e-1)" "unprognostic (2.18e-2)" "unprognostic (3.92e-1)" "unprognostic (8.78e-2)" "unprognostic (2.68e-2)" "unprognostic (1.52e-1)" "unprognostic (6.08e-2)" "unprognostic (4.35e-2)" "unprognostic (2.85e-2)" "unprognostic (4.22e-1)" "unprognostic (4.41e-2)" "unprognostic (4.05e-2)" "unprognostic (1.26e-1)" "unprognostic (5.34e-1)" "unprognostic (2.37e-1)" "unprognostic (4.62e-1)" "unprognostic (6.53e-2)" PIP4K2A "PIP5K2A, PIP5KIIA, PIP5KIIalpha" ENSG00000150867 "Phosphatidylinositol-5-phosphate 4-kinase type 2 alpha" P48426 10 22534854-22714578 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 238.6" "Cell type enhanced" "Detected in many" "B-cells: 537.5;NK-cells: 1232.7;Oligodendrocytes: 2307.5;Platelets: 968.6;T-cells: 801.7" "Cell type enhanced" "Detected in all" "leukocyte: 1473.1;oligodendrocyte: 2968.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065440, HPA068771" Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA 5300000 "Cluster 15: NK-cells - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 30 "Golgi apparatus" "Plasma membrane, Cytosol" "HPA065440: , HPA068771: " "unprognostic (1.29e-1)" "unprognostic (2.44e-1)" "potential prognostic favorable (2.75e-4)" "unprognostic (4.58e-1)" "unprognostic (1.18e-1)" "unprognostic (4.86e-3)" "unprognostic (3.21e-1)" "potential prognostic favorable (9.04e-4)" "unprognostic (4.70e-2)" "potential prognostic unfavorable (1.60e-5)" "potential prognostic favorable (3.63e-7)" "unprognostic (2.80e-1)" "unprognostic (9.40e-3)" "potential prognostic unfavorable (8.14e-4)" "unprognostic (9.08e-2)" "unprognostic (1.12e-1)" "unprognostic (2.11e-3)" "unprognostic (3.65e-1)" "unprognostic (2.55e-1)" "unprognostic (2.51e-2)" "unprognostic (1.44e-2)" "unprognostic (1.66e-1)" "unprognostic (6.70e-2)" "unprognostic (9.24e-2)" "unprognostic (2.41e-1)" "unprognostic (2.56e-1)" "unprognostic (2.58e-1)" "unprognostic (1.24e-3)" "unprognostic (1.36e-1)" "unprognostic (2.12e-2)" "unprognostic (4.68e-1)" PIP4K2B "PIP5K2B, PIP5KIIB, PIP5KIIbeta" ENSG00000276293 "Phosphatidylinositol-5-phosphate 4-kinase type 2 beta" P78356 17 38765691-38800126 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 29.1;Bergmann glia: 29.4;Brain excitatory neurons: 42.6;Brain inhibitory neurons: 46.4;Choroid plexus epithelial cells: 21.9;Distal convoluted tubule cells: 38.1;Ependymal cells: 23.2;Loop of henle epithelial cells: 31.3;Microglia: 34.7;Oligodendrocyte progenitor cells: 32.4;Oligodendrocytes: 32.9;Other brain neurons: 41.4;Papillary tip epithelial cells: 19.9;Podocytes: 39.5;Proximal tubule cells: 30.7;Renal collecting duct intercalated cells: 23.2;Renal collecting duct principal cells: 21.4;Renal connecting tubule cells: 29.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062220 Supported Nucleoplasm NA NA "Cluster 11: T-cells - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 102: Non-specific - Mixed function" 16 Nucleoplasm "HPA062220: " "unprognostic (5.50e-2)" "unprognostic (7.30e-2)" "unprognostic (2.10e-1)" "unprognostic (4.18e-2)" "unprognostic (7.00e-2)" "unprognostic (7.60e-2)" "unprognostic (4.31e-1)" "unprognostic (1.47e-1)" "unprognostic (1.04e-1)" "potential prognostic favorable (1.78e-4)" "unprognostic (4.07e-3)" "unprognostic (1.64e-1)" "unprognostic (1.13e-3)" "unprognostic (1.75e-2)" "unprognostic (2.94e-1)" "unprognostic (9.98e-2)" "unprognostic (2.63e-1)" "unprognostic (1.94e-3)" "unprognostic (6.24e-3)" "unprognostic (1.87e-2)" "unprognostic (3.63e-1)" "unprognostic (7.85e-2)" "unprognostic (2.30e-2)" "unprognostic (3.75e-1)" "unprognostic (9.25e-2)" "unprognostic (2.77e-1)" "unprognostic (8.83e-2)" "unprognostic (1.20e-1)" PIP4K2C "FLJ22055, PIP5K2C" ENSG00000166908 "Phosphatidylinositol-5-phosphate 4-kinase type 2 gamma" Q8TBX8 12 57591174-57603418 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 72.9;Foveolar cells: 94.9;Late spermatids: 72.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028658 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 22: Epididymis - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 68: Foveolar cells - Mucosal defense" 29 Cytosol "Nucleoplasm, Plasma membrane" "HPA028658: " "unprognostic (1.86e-1)" "unprognostic (2.77e-3)" "unprognostic (3.48e-2)" "unprognostic (1.86e-2)" "unprognostic (2.20e-2)" "unprognostic (3.90e-2)" "unprognostic (1.28e-1)" "unprognostic (2.61e-1)" "unprognostic (9.07e-2)" "unprognostic (6.56e-2)" "potential prognostic favorable (4.04e-4)" "unprognostic (3.84e-2)" "unprognostic (1.18e-1)" "unprognostic (4.46e-3)" "unprognostic (1.65e-2)" "unprognostic (7.03e-3)" "unprognostic (1.33e-2)" "unprognostic (4.30e-2)" "unprognostic (2.47e-1)" "unprognostic (1.63e-1)" "unprognostic (4.85e-2)" "unprognostic (1.16e-1)" "unprognostic (5.02e-2)" "unprognostic (2.96e-1)" "unprognostic (3.23e-3)" "unprognostic (8.02e-3)" "unprognostic (3.91e-2)" "unprognostic (2.31e-1)" "unprognostic (1.35e-1)" "unprognostic (1.56e-1)" "unprognostic (6.67e-2)" PIP4P1 "C14orf9, MGC26684, TMEM55B" ENSG00000165782 "Phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1" Q86T03 14 20457681-20461465 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 93.2;Syncytiotrophoblasts: 204.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048528 Approved NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 1: Neurons - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 28 "HPA048528: " "unprognostic (2.35e-3)" "unprognostic (2.25e-1)" "unprognostic (7.98e-2)" "unprognostic (3.35e-2)" "unprognostic (2.23e-2)" "unprognostic (1.75e-1)" "unprognostic (3.49e-3)" "unprognostic (1.03e-1)" "unprognostic (2.21e-2)" "potential prognostic favorable (3.37e-5)" "unprognostic (3.96e-2)" "potential prognostic favorable (7.71e-4)" "unprognostic (1.11e-2)" "unprognostic (6.91e-2)" "unprognostic (5.74e-2)" "unprognostic (1.44e-1)" "unprognostic (1.21e-1)" "unprognostic (7.58e-2)" "unprognostic (3.87e-1)" "unprognostic (2.64e-1)" "unprognostic (2.10e-2)" "unprognostic (2.40e-1)" "unprognostic (6.14e-2)" "unprognostic (9.81e-2)" "unprognostic (3.06e-1)" "unprognostic (1.38e-1)" "unprognostic (1.37e-1)" "unprognostic (2.24e-1)" "unprognostic (9.63e-3)" PIP4P2 "DKFZp762O076, TMEM55A" ENSG00000155099 "Phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2" Q8N4L2 8 90993802-91040872 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Megakaryocytes: 154.5;Neutrophil progenitors: 500.9;Neutrophils: 413.3;Platelets: 361.3;Retinal pigment epithelial cells: 200.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 7 "neutrophil: 77.2" "Lineage enriched" "Detected in all" 7 "granulocytes: 77.2" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014591 Approved NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 21: Non-specific - Metabolism" "Cluster 3: Rhabdoid - Membrane components" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 19 "HPA014591: " "unprognostic (3.89e-2)" "unprognostic (1.03e-1)" "unprognostic (3.17e-3)" "unprognostic (2.17e-2)" "unprognostic (7.03e-2)" "unprognostic (3.29e-1)" "unprognostic (8.30e-3)" "potential prognostic unfavorable (1.36e-4)" "unprognostic (2.44e-1)" "potential prognostic favorable (6.89e-5)" "unprognostic (5.80e-2)" "unprognostic (6.92e-2)" "potential prognostic unfavorable (7.96e-4)" "unprognostic (9.51e-3)" "unprognostic (1.49e-2)" "unprognostic (5.22e-2)" "unprognostic (8.65e-2)" "unprognostic (3.13e-2)" "unprognostic (1.40e-3)" "unprognostic (2.61e-2)" "unprognostic (8.71e-3)" "unprognostic (9.50e-2)" "unprognostic (3.78e-1)" "unprognostic (1.27e-2)" "unprognostic (1.94e-2)" "potential prognostic unfavorable (3.11e-5)" "unprognostic (2.91e-1)" "unprognostic (2.88e-2)" "unprognostic (2.65e-3)" PIP5K1A ENSG00000143398 "Phosphatidylinositol-4-phosphate 5-kinase type 1 alpha" Q99755 1 151197949-151249536 "Cancer-related genes, Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029366 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 39: Testis - Nuclear processes" "Cluster 48: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 100: Stratified epithelial cells - Barrier functions" 9 "Plasma membrane, Cytosol" Nucleoplasm "HPA029366: " "unprognostic (1.20e-1)" "unprognostic (9.12e-3)" "unprognostic (1.59e-1)" "unprognostic (7.64e-2)" "unprognostic (8.85e-2)" "unprognostic (1.27e-1)" "unprognostic (2.36e-1)" "unprognostic (4.13e-2)" "unprognostic (4.41e-2)" "unprognostic (3.14e-2)" "unprognostic (2.14e-1)" "unprognostic (4.47e-3)" "unprognostic (7.85e-3)" "unprognostic (4.14e-3)" "unprognostic (2.20e-1)" "unprognostic (9.03e-2)" "unprognostic (1.36e-1)" "unprognostic (1.40e-1)" "unprognostic (3.17e-1)" "unprognostic (9.35e-2)" "unprognostic (2.11e-1)" "unprognostic (1.34e-1)" "unprognostic (2.80e-2)" "unprognostic (6.93e-2)" "unprognostic (5.80e-2)" "unprognostic (2.36e-1)" "unprognostic (2.17e-1)" "unprognostic (2.66e-1)" "unprognostic (1.56e-1)" "unprognostic (3.76e-2)" "unprognostic (7.01e-2)" PIP5K1B "MSS4, STM7" ENSG00000107242 "Phosphatidylinositol-4-phosphate 5-kinase type 1 beta" O14986 9 68705240-69009176 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 111.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 1225.2;Choroid plexus epithelial cells: 2407.1;Colonocytes: 581.3;Foveolar cells: 659.7;Megakaryocyte-Erythroid progenitors: 498.3;Pituicytes/FSCs: 549.9;Retinal pigment epithelial cells: 626.7;Sertoli cells: 699.2" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 2334.6" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 5 "choroid plexus: 209.2" "Immune cell enriched" "Detected in many" 6 "eosinophil: 34.6" "Lineage enriched" "Detected in many" 6 "granulocytes: 34.6" "Cancer enhanced" "Detected in many" "colorectal cancer: 16.2" "Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009687 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 1 Nucleoplasm Vesicles "HPA009687: " "unprognostic (1.78e-2)" "potential prognostic favorable (8.70e-4)" "unprognostic (4.39e-2)" "unprognostic (6.55e-2)" "unprognostic (1.01e-1)" "unprognostic (6.46e-2)" "unprognostic (3.85e-2)" "unprognostic (3.70e-2)" "unprognostic (1.06e-1)" "validated prognostic favorable (3.88e-6)" "validated prognostic favorable (5.42e-5)" "potential prognostic favorable (4.60e-5)" "unprognostic (3.15e-2)" "unprognostic (2.53e-2)" "unprognostic (5.30e-3)" "unprognostic (2.50e-1)" "unprognostic (1.83e-2)" "unprognostic (1.23e-1)" "unprognostic (2.68e-2)" "unprognostic (8.09e-2)" "potential prognostic favorable (7.32e-4)" "unprognostic (8.05e-3)" "unprognostic (6.24e-2)" "unprognostic (4.99e-2)" "unprognostic (4.03e-2)" "unprognostic (3.69e-2)" "unprognostic (4.66e-2)" "unprognostic (2.16e-1)" "unprognostic (7.03e-2)" PIP5K1C "KIAA0589, LCCS3, PIP5Kgamma" ENSG00000186111 "Phosphatidylinositol-4-phosphate 5-kinase type 1 gamma" O60331 19 3630183-3700468 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell adhesion, Chemotaxis, Endocytosis, Exocytosis, Lipid metabolism, Phagocytosis" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 116.0" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Lung - Smooth muscle cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017168 Approved Supported Nucleoplasm,Cytosol No No "Cluster 13: Non-specific - Mitochondria" "Cluster 64: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 13 Nucleoplasm Cytosol "HPA017168: " "potential prognostic favorable (5.65e-4)" "unprognostic (1.24e-1)" "unprognostic (1.27e-2)" "unprognostic (1.65e-1)" "unprognostic (4.68e-2)" "unprognostic (1.14e-3)" "unprognostic (1.36e-1)" "unprognostic (1.17e-1)" "unprognostic (1.22e-2)" "unprognostic (1.78e-1)" "unprognostic (3.95e-3)" "unprognostic (2.47e-2)" "unprognostic (1.24e-1)" "unprognostic (5.58e-3)" "unprognostic (5.52e-2)" "unprognostic (1.59e-1)" "unprognostic (1.93e-1)" "unprognostic (5.30e-2)" "unprognostic (2.83e-2)" "unprognostic (1.78e-3)" "unprognostic (2.63e-1)" "unprognostic (6.17e-3)" "unprognostic (6.36e-2)" "unprognostic (1.39e-1)" "unprognostic (1.16e-1)" "unprognostic (2.47e-2)" "unprognostic (2.27e-1)" "unprognostic (1.58e-1)" "unprognostic (6.51e-2)" "unprognostic (5.24e-2)" "unprognostic (8.23e-3)" PIP5KL1 "bA203J24.5, MGC46424" ENSG00000167103 "Phosphatidylinositol-4-phosphate 5-kinase like 1" Q5T9C9 9 127920881-127930785 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 35.9;Early spermatids: 24.6;Foveolar cells: 18.6;Late spermatids: 39.6" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 6.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 10.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA056240 Uncertain Supported Cytosol NA NA "Cluster 2: Non-specific - Mixed function" "Cluster 24: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 68: Foveolar cells - Mucosal defense" Cytosol "HPA056240: " "unprognostic (3.17e-2)" "unprognostic (1.40e-1)" "unprognostic (1.61e-1)" "unprognostic (2.02e-2)" "unprognostic (1.33e-3)" "unprognostic (1.56e-2)" "unprognostic (7.64e-3)" "unprognostic (2.24e-1)" "unprognostic (5.84e-3)" "unprognostic (3.35e-2)" "unprognostic (4.12e-2)" "unprognostic (1.16e-1)" "unprognostic (6.57e-3)" "potential prognostic unfavorable (2.94e-4)" "unprognostic (5.30e-1)" "unprognostic (2.14e-1)" "unprognostic (1.49e-3)" PIPOX LPIPOX ENSG00000179761 "Pipecolic acid and sarcosine oxidase" Q9P0Z9 17 28950513-29057216 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 13 "kidney: 136.1;liver: 473.5" "Cell type enhanced" "Detected in many" "Early spermatids: 189.9;Hepatocytes: 270.6;Late spermatids: 864.1" "Cell type enhanced" "Detected in all" "astrocyte: 51.8;Bergmann glia: 57.2" "Group enriched" "Detected in many" 11 "Glioblastoma Multiforme (TCGA): 42.2;Liver Hepatocellular Carcinoma (TCGA): 165.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 1.8" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Brain cancer: 12.2;Sarcoma: 11.1" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Pituitary gland - Thyrotropes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA 290000 "Cluster 16: Liver & Kidney - Metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 4 "unprognostic (1.29e-1)" "unprognostic (2.58e-2)" "unprognostic (2.82e-1)" "unprognostic (3.50e-3)" "unprognostic (1.67e-1)" "unprognostic (1.00e-2)" "unprognostic (1.04e-1)" "potential prognostic unfavorable (9.28e-4)" "unprognostic (3.87e-2)" "potential prognostic favorable (8.74e-4)" "unprognostic (4.72e-1)" "unprognostic (4.87e-2)" "unprognostic (2.70e-3)" "unprognostic (6.65e-3)" "unprognostic (3.46e-3)" "unprognostic (2.12e-1)" "unprognostic (3.85e-1)" "unprognostic (2.32e-1)" "unprognostic (4.85e-1)" "unprognostic (9.38e-2)" "potential prognostic favorable (1.67e-4)" "unprognostic (2.64e-1)" "unprognostic (1.49e-1)" "unprognostic (2.27e-1)" "unprognostic (4.45e-3)" "unprognostic (1.42e-2)" "unprognostic (3.45e-1)" "unprognostic (1.07e-1)" PIR ENSG00000087842 Pirin O00625 X 15384799-15493564 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 171.3;Melanocytes: 202.1;Myonuclei: 224.2;Urothelial cells: 183.5" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 142.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000697, HPA075091" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 13000 "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 2 Nucleoplasm "Nuclear bodies, Cytosol" "HPA000697: , HPA075091: " "unprognostic (5.42e-2)" "unprognostic (9.64e-3)" "unprognostic (2.33e-1)" "unprognostic (1.18e-2)" "unprognostic (4.59e-2)" "unprognostic (1.54e-1)" "unprognostic (1.69e-3)" "potential prognostic unfavorable (4.03e-5)" "unprognostic (1.74e-2)" "unprognostic (2.71e-3)" "unprognostic (1.12e-1)" "unprognostic (1.49e-2)" "potential prognostic unfavorable (7.64e-5)" "unprognostic (1.27e-3)" "unprognostic (2.78e-2)" "unprognostic (1.12e-3)" "unprognostic (1.04e-1)" "unprognostic (8.64e-3)" "unprognostic (1.54e-1)" "unprognostic (8.69e-3)" "unprognostic (4.92e-3)" "unprognostic (2.13e-2)" "unprognostic (1.84e-1)" "unprognostic (1.01e-1)" "unprognostic (1.16e-1)" "unprognostic (4.19e-1)" "unprognostic (1.02e-1)" "unprognostic (1.30e-2)" "unprognostic (1.62e-1)" "unprognostic (1.57e-1)" "unprognostic (2.04e-2)" PIRT ENSG00000233670 "Phosphoinositide interacting regulator of transient receptor potential channels" P0C851 17 10822470-10838087 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 11.9;intestine: 4.1" "Group enriched" "Detected in some" 7 "Astrocytes: 20.5;Bergmann glia: 22.0;Ependymal cells: 16.3" "Group enriched" "Detected in some" 7 "astrocyte: 46.9;Bergmann glia: 25.7;ependymal cell: 21.7" "Cancer enriched" "Detected in single" 43 "Glioblastoma Multiforme (TCGA): 9.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 51 "Neuroblastoma: 5.1" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA042337 Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 28: Astrocytes - Homeostasis & neuron support" Cytosol "Plasma membrane" "HPA042337: " "unprognostic (5.24e-3)" "unprognostic (1.12e-3)" PISD "dJ858B16.2, PSDC" ENSG00000241878 "Phosphatidylserine decarboxylase" Q9UG56 22 31618491-31662221 "Disease related genes, Enzymes, Essential proteins, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Decarboxylase, Lyase" "Cataract, Deafness, Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 319.7;Endometrial glandular cells: 548.5;Endometrial luminal cells: 418.0;Syncytiotrophoblasts: 279.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 39.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031090, HPA031091" Approved Supported "Golgi apparatus,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 64: Non-specific - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 51: Secretory epithelial cells - Mixed function" 2 Cytosol "Golgi apparatus" "HPA031090: , HPA031091: " "unprognostic (1.12e-1)" "unprognostic (2.29e-1)" "unprognostic (2.13e-1)" "unprognostic (1.35e-2)" "unprognostic (3.02e-2)" "unprognostic (1.72e-1)" "unprognostic (2.28e-2)" "unprognostic (9.04e-3)" "unprognostic (1.36e-1)" "unprognostic (1.39e-1)" "unprognostic (2.64e-1)" "unprognostic (2.56e-1)" "unprognostic (1.48e-1)" "unprognostic (9.01e-2)" "unprognostic (3.36e-1)" "unprognostic (6.07e-2)" "unprognostic (1.77e-1)" "unprognostic (1.17e-1)" "unprognostic (1.13e-1)" "unprognostic (1.37e-1)" "unprognostic (1.70e-1)" "potential prognostic favorable (1.19e-5)" "unprognostic (1.64e-1)" "unprognostic (1.85e-1)" "unprognostic (1.47e-2)" "unprognostic (2.71e-2)" "potential prognostic unfavorable (7.87e-4)" "unprognostic (1.88e-1)" "unprognostic (2.86e-1)" "unprognostic (6.35e-2)" "unprognostic (1.08e-1)" PITHD1 "C1orf128, HT014, TXNL1CL" ENSG00000057757 "PITH domain containing 1" Q9GZP4 1 23778418-23788232 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 290.9;Esophageal suprabasal cells: 231.4;Oocytes: 336.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016936 Uncertain NA NA 350000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 14: Neurons - Synaptic function" "Cluster 37: Non-specific - mRNA processing" "Cluster 20: Non-specific - Transcription regulation" 4 "HPA016936: " "unprognostic (1.77e-1)" "unprognostic (1.04e-1)" "unprognostic (1.90e-1)" "unprognostic (1.15e-1)" "unprognostic (1.87e-1)" "unprognostic (1.22e-2)" "unprognostic (9.82e-2)" "unprognostic (2.26e-1)" "unprognostic (2.60e-2)" "unprognostic (5.90e-3)" "unprognostic (8.44e-3)" "unprognostic (1.27e-2)" "potential prognostic unfavorable (3.23e-4)" "unprognostic (2.32e-2)" "unprognostic (1.08e-1)" "unprognostic (8.98e-2)" "unprognostic (1.59e-3)" "unprognostic (3.57e-1)" "unprognostic (4.96e-2)" "unprognostic (1.46e-1)" "unprognostic (1.60e-1)" "unprognostic (6.16e-2)" "unprognostic (1.52e-1)" "unprognostic (2.61e-2)" "unprognostic (8.79e-2)" "unprognostic (7.11e-3)" "unprognostic (3.84e-1)" "unprognostic (1.31e-1)" "unprognostic (1.00e-1)" "unprognostic (1.39e-3)" PITPNA "PITPN, VIB1A" ENSG00000174238 "Phosphatidylinositol transfer protein alpha" Q00169 17 1517718-1562792 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 766.4;Retinal pigment epithelial cells: 1334.3;Syncytiotrophoblasts: 382.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000528 Uncertain Approved Vesicles,Cytosol NA NA 120000 "Cluster 35: Neutrophils - Protein binding" "Cluster 55: Breast - Lactation" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 42: Non-specific - Unknown function" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 6 Cytosol Vesicles "HPA000528: " "unprognostic (3.91e-3)" "unprognostic (3.01e-2)" "unprognostic (1.24e-1)" "unprognostic (9.90e-3)" "unprognostic (1.37e-2)" "unprognostic (2.49e-2)" "unprognostic (4.18e-2)" "unprognostic (2.90e-2)" "unprognostic (1.56e-2)" "unprognostic (1.73e-2)" "potential prognostic favorable (9.24e-5)" "unprognostic (2.44e-3)" "unprognostic (1.79e-2)" "unprognostic (1.42e-1)" "unprognostic (4.85e-2)" "unprognostic (4.81e-2)" "unprognostic (3.90e-1)" "unprognostic (2.87e-3)" "unprognostic (1.21e-1)" "unprognostic (2.30e-1)" "unprognostic (9.61e-3)" "unprognostic (1.47e-3)" "unprognostic (1.37e-1)" "unprognostic (3.28e-2)" "unprognostic (1.87e-1)" "unprognostic (1.39e-1)" "unprognostic (2.44e-1)" "unprognostic (1.46e-1)" "unprognostic (1.16e-1)" "unprognostic (3.35e-1)" "unprognostic (1.74e-2)" PITPNB VIB1B ENSG00000180957 "Phosphatidylinositol transfer protein beta" P48739 22 27851669-27920134 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000528 Uncertain Approved Vesicles,Cytosol NA NA 200000 "Cluster 16: Non-specific - Cell proliferation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 14: Neurons - Synaptic function" "Cluster 66: Non-specific - Mitochondria" "Cluster 103: Non-specific - Basic cellular processes" 3 "Vesicles, Cytosol" "HPA000528: " "unprognostic (2.43e-1)" "unprognostic (5.29e-2)" "unprognostic (2.15e-1)" "unprognostic (1.29e-1)" "unprognostic (9.89e-2)" "unprognostic (1.46e-1)" "unprognostic (1.97e-1)" "unprognostic (2.28e-1)" "potential prognostic unfavorable (1.77e-4)" "unprognostic (1.59e-3)" "potential prognostic favorable (3.41e-4)" "unprognostic (4.44e-3)" "unprognostic (1.67e-1)" "unprognostic (1.31e-1)" "unprognostic (5.34e-2)" "potential prognostic unfavorable (4.58e-4)" "unprognostic (4.91e-3)" "unprognostic (1.57e-1)" "unprognostic (1.05e-2)" "unprognostic (6.98e-2)" "unprognostic (4.47e-2)" "unprognostic (8.81e-3)" "potential prognostic unfavorable (1.07e-4)" "unprognostic (1.86e-1)" "unprognostic (1.96e-2)" "unprognostic (7.40e-2)" "unprognostic (1.55e-1)" "unprognostic (5.77e-2)" "unprognostic (2.59e-1)" "unprognostic (3.44e-2)" "unprognostic (1.21e-1)" PITPNC1 "RDGB-BETA, RDGBB, RDGBB1" ENSG00000154217 "Phosphatidylinositol transfer protein cytoplasmic 1" Q9UKF7 17 67377281-67697256 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 24.4" "Cell type enhanced" "Detected in many" "Astrocytes: 2098.3;Bergmann glia: 1275.9;Choroid plexus epithelial cells: 1141.8;NK-cells: 1400.8;Pancreatic acinar cells: 1495.5;Pituicytes/FSCs: 1514.3;T-cells: 1098.5;Vascular endothelial cells: 1075.9" "Cell type enhanced" "Detected in all" "astrocyte: 2614.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026563, HPA031250" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 78: Brain - Neuronal signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 2 Cytosol Nucleoplasm "HPA026563: , HPA031250: " "unprognostic (1.20e-2)" "unprognostic (1.74e-1)" "unprognostic (2.53e-2)" "unprognostic (1.56e-3)" "unprognostic (3.69e-1)" "unprognostic (2.45e-1)" "unprognostic (2.12e-1)" "unprognostic (6.35e-2)" "unprognostic (1.78e-2)" "unprognostic (1.95e-1)" "validated prognostic favorable (3.24e-8)" "validated prognostic favorable (2.37e-4)" "potential prognostic favorable (4.75e-4)" "unprognostic (9.50e-3)" "unprognostic (1.49e-1)" "unprognostic (1.12e-3)" "unprognostic (4.71e-1)" "unprognostic (1.17e-1)" "unprognostic (1.95e-1)" "unprognostic (2.61e-1)" "unprognostic (3.18e-1)" "unprognostic (9.16e-2)" "unprognostic (2.58e-3)" "unprognostic (2.46e-2)" "unprognostic (1.42e-1)" "unprognostic (1.99e-2)" "unprognostic (3.63e-2)" "unprognostic (2.69e-1)" "unprognostic (4.21e-2)" "unprognostic (2.10e-3)" "unprognostic (8.73e-3)" PITPNM1 "DRES9, NIR2, PITPNM, Rd9, RDGB, RDGB1, RDGBA1" ENSG00000110697 "Phosphatidylinositol transfer protein membrane associated 1" O00562 11 67491768-67506263 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 73.8;Epididymal efferent duct ciliated cells: 50.4;Fallopian tube ciliated cells: 78.4;Respiratory ciliated cells: 71.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Stomach - Gastric mucous cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060227 Approved Supported Vesicles,Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 107: Ciliated cells - Cilia assembly & function" 9 Cytosol Vesicles "HPA060227: " "unprognostic (3.14e-1)" "unprognostic (4.64e-2)" "unprognostic (1.58e-1)" "unprognostic (9.10e-2)" "unprognostic (6.23e-2)" "unprognostic (1.45e-2)" "unprognostic (3.99e-2)" "unprognostic (4.04e-1)" "unprognostic (9.63e-2)" "unprognostic (2.04e-1)" "potential prognostic favorable (8.36e-4)" "unprognostic (8.65e-2)" "unprognostic (1.36e-1)" "unprognostic (7.10e-2)" "unprognostic (1.38e-2)" "unprognostic (2.45e-1)" "unprognostic (8.56e-2)" "unprognostic (7.59e-3)" "unprognostic (6.40e-2)" "unprognostic (1.82e-3)" "unprognostic (1.99e-2)" "unprognostic (1.36e-1)" "unprognostic (2.87e-3)" "unprognostic (2.06e-2)" "unprognostic (2.10e-2)" "unprognostic (1.61e-1)" "unprognostic (1.88e-1)" "unprognostic (3.99e-2)" "unprognostic (2.21e-1)" "unprognostic (2.97e-1)" "unprognostic (1.02e-1)" PITPNM2 "NIR3, RDGB2, RDGBA2" ENSG00000090975 "Phosphatidylinositol transfer protein membrane associated 2" Q9BZ72 12 122983480-123151090 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 79.3" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 438.8;Cone photoreceptor cells: 573.4;Distal convoluted tubule cells: 203.8;Loop of henle epithelial cells: 173.5;Platelets: 259.5;Retinal bipolar cells: 179.2;Retinal horizontal cells: 198.3;Rod photoreceptor cells: 200.1" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 289.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 1.9" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003414, HPA003978" Approved Supported Vesicles NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 80: Thymus - Adaptive immune response" "Cluster 23: Choroid plexus - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 79: Photoreceptor cells - Phototransduction" 2 Vesicles "HPA003414: , HPA003978: " "unprognostic (2.01e-1)" "unprognostic (4.66e-2)" "unprognostic (2.10e-1)" "unprognostic (4.43e-2)" "unprognostic (8.82e-2)" "unprognostic (4.19e-2)" "unprognostic (1.55e-1)" "unprognostic (2.87e-3)" "unprognostic (4.07e-2)" "unprognostic (2.98e-1)" "unprognostic (2.52e-1)" "unprognostic (1.04e-2)" "unprognostic (1.53e-3)" "unprognostic (7.81e-2)" "unprognostic (6.07e-3)" "unprognostic (9.31e-2)" "unprognostic (2.08e-1)" "unprognostic (7.75e-3)" "unprognostic (8.40e-2)" "unprognostic (1.03e-1)" "unprognostic (1.27e-1)" "unprognostic (5.50e-2)" "potential prognostic unfavorable (7.14e-5)" "unprognostic (2.66e-1)" "unprognostic (3.23e-2)" "unprognostic (4.96e-3)" "unprognostic (3.45e-2)" "unprognostic (1.32e-1)" "unprognostic (2.91e-1)" "unprognostic (3.76e-2)" "unprognostic (1.34e-3)" PITPNM3 "ACKR6, CORD5, NIR1, RDGBA3" ENSG00000091622 "PITPNM family member 3" Q9BZ71 17 6451263-6556555 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 37.5;lymphoid tissue: 57.5" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 51.5;Esophageal apical cells: 44.8;Esophageal suprabasal cells: 48.4;Respiratory basal cells: 49.8;Respiratory deuterosomal cells: 50.8;Respiratory secretory cells: 54.1;Transitional alveolar cells: 44.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 23 "neutrophil: 2.2" "Lineage enriched" "Detected in single" 23 "granulocytes: 2.2" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Liver - Sinusoid Endothelial cells, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary gland basal cells, Spleen - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022432, HPA059005" Enhanced Approved "Plasma membrane" NA NA "Cluster 5: Spleen - Immune response" "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 4 "Plasma membrane" "HPA022432: , HPA059005: " "unprognostic (5.95e-2)" "unprognostic (1.94e-2)" "unprognostic (6.76e-2)" "unprognostic (1.77e-1)" "unprognostic (6.84e-2)" "unprognostic (1.08e-1)" "unprognostic (2.96e-2)" "unprognostic (7.13e-2)" "potential prognostic favorable (1.94e-6)" "unprognostic (1.98e-3)" "unprognostic (1.69e-1)" "unprognostic (1.76e-1)" "unprognostic (1.26e-1)" "unprognostic (1.65e-2)" "unprognostic (8.47e-2)" "unprognostic (2.15e-2)" "unprognostic (1.55e-3)" "unprognostic (6.97e-2)" "unprognostic (5.03e-2)" "unprognostic (8.99e-2)" "unprognostic (1.64e-1)" "unprognostic (3.02e-2)" "unprognostic (3.42e-2)" "unprognostic (1.74e-1)" "unprognostic (1.26e-1)" "unprognostic (2.29e-2)" PITRM1 "hMP1, KIAA1104, MP1, PreP" ENSG00000107959 "Pitrilysin metallopeptidase 1" Q5JRX3 10 3137728-3172841 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 216.7;Late spermatids: 131.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006753, HPA006754" Enhanced Supported Mitochondria NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 52: Non-specific - Mitochondria" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 2 Mitochondria "HPA006753: , HPA006754: " "unprognostic (4.31e-1)" "unprognostic (1.39e-3)" "unprognostic (6.04e-2)" "unprognostic (7.27e-3)" "unprognostic (5.37e-2)" "unprognostic (2.17e-2)" "unprognostic (6.20e-2)" "potential prognostic favorable (1.97e-5)" "unprognostic (2.98e-1)" "unprognostic (4.34e-2)" "unprognostic (1.13e-1)" "unprognostic (2.48e-1)" "unprognostic (3.09e-1)" "unprognostic (2.84e-2)" "unprognostic (5.13e-3)" "unprognostic (1.24e-1)" "unprognostic (1.56e-1)" "unprognostic (4.05e-2)" "unprognostic (6.46e-2)" "unprognostic (4.23e-1)" "unprognostic (2.49e-1)" "unprognostic (1.13e-1)" "unprognostic (4.01e-2)" "unprognostic (1.87e-1)" "unprognostic (2.46e-1)" "unprognostic (4.62e-2)" "unprognostic (4.41e-2)" "unprognostic (2.21e-1)" "unprognostic (1.03e-1)" "unprognostic (1.78e-2)" "unprognostic (2.89e-1)" PITX1 "BFT, POTX, PTX1" ENSG00000069011 "Paired like homeodomain 1" P78337 5 135027734-135034813 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 701.1;vagina: 194.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 313.2;Esophageal apical cells: 3695.3;Esophageal basal cells: 919.0;Esophageal suprabasal cells: 1804.8;Suprabasal keratinocytes: 838.0" "Cell type enriched" "Detected in single" 43 "choroid plexus epithelial cell: 8.2" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 163.5" "Region enriched" "Detected in all" 4 "choroid plexus: 9.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 136.9" "Minor Salivary Gland - Minor salivary gland basal cells, Stomach - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA008743 Approved Supported Nucleoli Yes No "Cluster 81: Squamous epithelium - Keratinization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 70 Nucleoli "HPA008743: " "unprognostic (4.51e-2)" "unprognostic (8.87e-2)" "unprognostic (1.79e-1)" "unprognostic (3.25e-1)" "unprognostic (4.22e-2)" "unprognostic (6.03e-2)" "unprognostic (4.09e-2)" "unprognostic (3.13e-2)" "unprognostic (7.76e-3)" "unprognostic (3.70e-3)" "potential prognostic unfavorable (3.22e-15)" "unprognostic (5.50e-3)" "unprognostic (4.26e-3)" "unprognostic (6.14e-3)" "unprognostic (4.54e-2)" "unprognostic (1.68e-3)" "unprognostic (3.49e-2)" "unprognostic (3.05e-2)" "unprognostic (7.30e-2)" "unprognostic (8.64e-2)" "unprognostic (1.72e-1)" "unprognostic (6.81e-3)" "unprognostic (2.58e-1)" "unprognostic (2.35e-1)" "unprognostic (3.13e-2)" "unprognostic (3.96e-2)" "unprognostic (7.00e-2)" "unprognostic (9.49e-2)" "unprognostic (3.04e-2)" "unprognostic (3.60e-2)" PITX2 "ARP1, Brx1, IGDS, IHG2, IRID2, Otlx2, RGS, RIEG, RIEG1, RS" ENSG00000164093 "Paired like homeodomain 2" Q99697 4 110617423-110642123 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Disease variant, Peters anomaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 39.5;skeletal muscle: 40.4;tongue: 26.2;urinary bladder: 26.9" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 40.2;Enterocytes: 42.4;Epididymal efferent duct absorptive cells: 37.3;Fibroblasts: 53.2;Gonadotrophs: 90.1;Myonuclei: 34.7;Myosatellite cells: 54.2;Paneth cells: 27.1;Pituitary stem cells: 52.1;Smooth muscle cells: 27.6;Suprabasal keratinocytes: 48.3;Thymic myoid cells: 93.8;Thyrotrophs: 65.5" "Cell type enriched" "Detected in some" 28 "mammillary body: 75.2" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 4 "hypothalamus: 29.9;thalamus: 10.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 23 "hypothalamus: 8.6;midbrain: 2.3" "HPA050074, HPA062728" Enhanced "Nucleoplasm,Primary cilium tip" NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 19: Astrocytes - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 108: Fibroblasts - ECM organization" 4 Nucleoplasm "Primary cilium tip" "HPA050074: , HPA062728: " "unprognostic (2.26e-2)" "unprognostic (1.79e-1)" "unprognostic (2.80e-2)" "unprognostic (3.42e-1)" "unprognostic (3.07e-1)" "unprognostic (9.42e-2)" "unprognostic (2.91e-3)" "potential prognostic unfavorable (9.96e-5)" "unprognostic (6.27e-3)" "potential prognostic unfavorable (4.07e-7)" "unprognostic (4.27e-2)" "unprognostic (4.00e-2)" "unprognostic (2.11e-1)" "unprognostic (1.21e-1)" "unprognostic (3.64e-3)" "unprognostic (8.82e-2)" "unprognostic (4.92e-3)" "unprognostic (2.19e-2)" "unprognostic (2.19e-1)" "unprognostic (1.47e-1)" PITX3 ASMD ENSG00000107859 "Paired like homeodomain 3" O75364 10 102230186-102241512 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cataract, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.3;skeletal muscle: 15.5;tongue: 5.6" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 5.2;Early spermatids: 24.5;Late spermatids: 10.1;Myonuclei: 12.4;Myosatellite cells: 13.5" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 15 "midbrain: 12.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 15 "Sarcoma: 13.7" "Testis - Late spermatids" "Not detected" "Not detected" "Region enhanced" "Detected in some" "midbrain: 11.9" NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 1 PIWIL1 "CT80.1, HIWI, PIWI" ENSG00000125207 "Piwi like RNA-mediated gene silencing 1" Q96J94 12 130337887-130372637 "Disease related genes, Predicted intracellular proteins" "Differentiation, Meiosis, RNA-mediated gene silencing, Spermatogenesis, Translation regulation" "Developmental protein, Endonuclease, Hydrolase, Nuclease, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 36 "testis: 39.9" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 8.3;Early primary spermatocytes: 10.2;Early spermatids: 30.1;Late primary spermatocytes: 71.6;Late spermatids: 23.4;Rod photoreceptor cells: 16.1" "Group enriched" "Detected in some" 5 "deep-layer corticothalamic and 6b: 4.5;deep-layer near-projecting: 14.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "colorectal cancer: 3.0;Gastric cancer: 2.1" "Testis - Early spermatids, Testis - Spermatocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA066880 Enhanced NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 9 "HPA066880: " "unprognostic (2.98e-3)" "unprognostic (1.81e-2)" "unprognostic (1.25e-1)" PIWIL2 "CT80, FLJ10351, HILI, Mili" ENSG00000197181 "Piwi like RNA-mediated gene silencing 2" Q8TC59 8 22275316-22357568 "Predicted intracellular proteins" "Biological rhythms, Differentiation, Meiosis, Oogenesis, RNA-mediated gene silencing, Spermatogenesis, Translation regulation" "Developmental protein, Endonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 26.9" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 49.8;Early primary spermatocytes: 99.7;Endometrial luminal cells: 26.1;Undifferentiated spermatogonia: 129.7" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in some" 6 "Testicular Germ Cell Tumor (TCGA): 10.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 2.7" "Testis - Spermatocytes, Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 1: Neuronal - Visual perception" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 4 "unprognostic (9.53e-2)" "unprognostic (1.36e-1)" "unprognostic (6.00e-2)" "unprognostic (2.58e-2)" "unprognostic (1.45e-2)" "unprognostic (3.21e-1)" "unprognostic (3.87e-2)" "unprognostic (6.60e-2)" "unprognostic (4.63e-2)" "unprognostic (4.18e-2)" PIWIL3 HIWI3 ENSG00000184571 "Piwi like RNA-mediated gene silencing 3" Q7Z3Z3 22 24719034-24774720 "Predicted intracellular proteins" "Differentiation, Meiosis, RNA-mediated gene silencing, Spermatogenesis, Translation regulation" "Developmental protein, RNA-binding" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Early spermatids: 40.0;Innate lymphoid cells: 37.1;Oocytes: 55.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Spermatocytes, Testis - Spermatogonia" "Not detected" "Not detected" HPA061955 Uncertain Approved "Cytoplasmic bodies" NA NA "Cluster 47: Leukemia - Hemostasis" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" "Cytoplasmic bodies" "HPA061955: " PIWIL4 "FLJ36156, HIWI2, Miwi2" ENSG00000134627 "Piwi like RNA-mediated gene silencing 4" Q7Z3Z4 11 94543840-94621421 "Predicted intracellular proteins" "Differentiation, Meiosis, RNA-mediated gene silencing, Spermatogenesis, Translation regulation" "Developmental protein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 22.9" "Cell type enhanced" "Detected in many" "Gastric progenitor cells: 55.1;Microglia: 47.5;Monocyte progenitors: 66.9;Neutrophil progenitors: 161.9;Neutrophils: 61.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 5.7;Leukemia: 11.1" "Prostate - Fibroblasts, Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA036587, HPA036588, HPA057508" Enhanced Supported Nucleoplasm,Mitochondria NA NA "Cluster 44: Bone marrow - Nuclear processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" "Nucleoplasm, Mitochondria" "HPA036587: , HPA036588: , HPA057508: " "unprognostic (9.98e-2)" "unprognostic (1.91e-1)" "unprognostic (1.60e-1)" "unprognostic (1.84e-3)" "unprognostic (1.11e-2)" "unprognostic (3.60e-2)" "unprognostic (7.72e-3)" "unprognostic (1.76e-2)" "unprognostic (1.55e-2)" "unprognostic (3.12e-2)" "unprognostic (2.60e-1)" "unprognostic (1.66e-2)" "unprognostic (1.66e-2)" "unprognostic (3.00e-2)" "unprognostic (2.90e-2)" "unprognostic (7.25e-2)" "unprognostic (1.70e-1)" "unprognostic (2.61e-1)" "unprognostic (2.59e-2)" "unprognostic (2.01e-1)" "unprognostic (8.36e-2)" "unprognostic (3.93e-2)" "unprognostic (4.76e-3)" "unprognostic (1.60e-1)" "unprognostic (2.11e-1)" "unprognostic (5.13e-2)" "potential prognostic unfavorable (8.68e-7)" PJA1 "FLJ11830, PRAJA1, RNF70" ENSG00000181191 "Praja ring finger ubiquitin ligase 1" Q8NG27 X 69160851-69165521 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 151.0" "Cell type enhanced" "Detected in many" "Early spermatids: 105.7;Epididymal principal cells: 150.1;Late spermatids: 43.9;Migrating cytotrophoblasts: 40.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Fibroblasts, Liver - Vascular endothelial cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000595 Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 24: Non-specific - Transcription" "Cluster 22: Epididymis - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 65: Non-specific - Unknown function" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" 19 "Nucleoplasm, Nucleoli" "HPA000595: " "unprognostic (1.34e-2)" "unprognostic (3.51e-2)" "unprognostic (2.18e-1)" "unprognostic (9.73e-2)" "unprognostic (2.69e-1)" "unprognostic (1.78e-1)" "unprognostic (1.97e-1)" "unprognostic (3.13e-3)" "unprognostic (3.35e-2)" "unprognostic (6.71e-3)" "potential prognostic favorable (7.61e-5)" "unprognostic (6.47e-3)" "unprognostic (6.73e-2)" "potential prognostic unfavorable (3.14e-4)" "unprognostic (3.88e-3)" "unprognostic (1.77e-1)" "unprognostic (2.27e-3)" "unprognostic (4.62e-2)" "unprognostic (2.40e-1)" "unprognostic (8.56e-2)" "unprognostic (8.43e-2)" "unprognostic (1.53e-1)" "unprognostic (1.28e-1)" "unprognostic (1.27e-1)" "unprognostic (4.31e-1)" "unprognostic (3.33e-2)" "unprognostic (2.37e-2)" "unprognostic (1.59e-1)" "unprognostic (2.33e-1)" "unprognostic (4.09e-1)" "unprognostic (1.29e-1)" PJA2 "KIAA0438, Neurodap1, PRAJA2, RNF131" ENSG00000198961 "Praja ring finger ubiquitin ligase 2" O43164 5 109334713-109409974 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 726.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039602, HPA040347" Supported Supported "Microtubules,Primary cilium,Primary cilium transition zone,Basal body,Cytosol" NA No "Cluster 35: Neutrophils - Protein binding" "Cluster 73: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 16 "Microtubules, Basal body, Cytosol" "Primary cilium, Primary cilium transition zone" "HPA039602: , HPA040347: " "unprognostic (1.33e-2)" "unprognostic (8.69e-2)" "unprognostic (4.18e-1)" "unprognostic (3.78e-2)" "unprognostic (1.96e-1)" "unprognostic (4.25e-1)" "unprognostic (2.46e-1)" "potential prognostic unfavorable (1.20e-4)" "unprognostic (3.03e-2)" "unprognostic (2.32e-3)" "validated prognostic favorable (1.54e-7)" "validated prognostic favorable (4.22e-4)" "unprognostic (1.53e-1)" "unprognostic (3.90e-1)" "unprognostic (5.72e-2)" "unprognostic (2.55e-1)" "unprognostic (4.57e-1)" "unprognostic (3.72e-2)" "unprognostic (4.55e-3)" "unprognostic (3.36e-3)" "potential prognostic unfavorable (1.57e-4)" "unprognostic (3.14e-1)" "unprognostic (4.61e-2)" "unprognostic (1.82e-1)" "unprognostic (1.50e-1)" "unprognostic (7.02e-2)" "unprognostic (2.53e-1)" "unprognostic (4.05e-3)" "unprognostic (2.14e-1)" "unprognostic (4.62e-2)" "unprognostic (3.61e-1)" PJVK DFNB59 ENSG00000204311 Pejvakin Q0ZLH3 2 178451346-178462102 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Hearing "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 37.1" "Cell type enhanced" "Detected in many" "Early spermatids: 224.4;Late primary spermatocytes: 237.6;Late spermatids: 140.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "plasmacytoid DC: 2.8" "Lineage enriched" "Detected in single" 5 "dendritic cells: 2.8" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA No "Cluster 21: Testis - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" "unprognostic (2.38e-1)" "unprognostic (1.04e-1)" "unprognostic (1.82e-2)" "potential prognostic unfavorable (4.80e-4)" "unprognostic (2.67e-1)" "unprognostic (1.38e-3)" "unprognostic (3.40e-1)" "unprognostic (1.34e-1)" "potential prognostic unfavorable (1.19e-6)" "unprognostic (2.87e-2)" "potential prognostic favorable (2.62e-4)" "unprognostic (8.81e-2)" "unprognostic (2.71e-1)" "unprognostic (2.38e-1)" "unprognostic (6.22e-2)" "unprognostic (2.81e-1)" "unprognostic (5.51e-2)" "unprognostic (1.30e-1)" "unprognostic (3.81e-2)" "unprognostic (1.56e-1)" "unprognostic (1.14e-1)" "unprognostic (1.45e-1)" "unprognostic (2.76e-2)" "unprognostic (2.69e-1)" "unprognostic (1.23e-1)" "unprognostic (7.06e-3)" "unprognostic (9.46e-2)" PKD1 "PBP, Pc-1, TRPP1" ENSG00000008710 "Polycystin 1, transient receptor potential channel interacting" P98161 16 2088708-2135898 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Wnt signaling pathway" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 199.9" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 154.3;Lactotrophs: 121.7;Somatotrophs: 127.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB046448 Approved "Secreted - unknown location" Other NA NA 1400000 "Cluster 64: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 35: Neurons - Synaptic function & neurogenesis" 12 "CAB046448: " "unprognostic (8.48e-2)" "unprognostic (2.51e-2)" "unprognostic (3.23e-2)" "unprognostic (9.63e-2)" "unprognostic (2.25e-2)" "unprognostic (1.63e-1)" "unprognostic (2.48e-1)" "unprognostic (1.24e-1)" "potential prognostic favorable (4.25e-4)" "unprognostic (2.94e-1)" "unprognostic (1.07e-2)" "unprognostic (3.41e-2)" "unprognostic (2.39e-1)" "unprognostic (4.04e-3)" "unprognostic (2.63e-1)" "unprognostic (9.14e-3)" "unprognostic (3.45e-1)" "unprognostic (1.02e-1)" "unprognostic (2.87e-2)" "unprognostic (1.27e-2)" "unprognostic (5.04e-2)" "unprognostic (1.94e-2)" "unprognostic (1.09e-1)" "unprognostic (2.67e-1)" "unprognostic (3.22e-2)" "unprognostic (3.35e-3)" "unprognostic (3.05e-1)" "unprognostic (3.68e-2)" "unprognostic (1.23e-1)" "unprognostic (1.62e-2)" "unprognostic (3.66e-2)" PKD1L1 PRO19563 ENSG00000158683 "Polycystin 1 like 1, transient receptor potential channel interacting" Q8TDX9 7 47740202-47948466 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" Heterotaxy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skeletal muscle: 2.6;tongue: 2.4" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 58.1;Myonuclei: 55.6;Other brain neurons: 40.0;Retinal amacrine cells: 47.8;Retinal bipolar cells: 126.5;Retinal horizontal cells: 68.1;Rod photoreceptor cells: 29.3;Vascular endothelial cells: 56.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 5.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose visceral - Endothelial cells, Liver - Vascular endothelial cells" "Not detected" "Not detected" "HPA020422, HPA022424" Uncertain NA NA "Cluster 40: Non-specific - Mixed function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 20: Myeloma - Immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "HPA020422: , HPA022424: " "unprognostic (1.33e-1)" "unprognostic (1.65e-1)" "unprognostic (1.76e-1)" "unprognostic (5.13e-2)" "unprognostic (1.36e-1)" "unprognostic (7.35e-3)" "unprognostic (1.45e-2)" "unprognostic (3.41e-2)" "unprognostic (1.67e-1)" "unprognostic (2.98e-1)" PKD1L2 KIAA1879 ENSG00000166473 "Polycystin 1 like 2 (gene/pseudogene)" Q7Z442 16 81100875-81220370 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 7.5;choroid plexus: 8.1;heart muscle: 7.4" "Cell type enhanced" "Detected in many" "Adipocytes: 125.8;Cardiomyocytes: 42.9;Choroid plexus epithelial cells: 372.7;Endometrial stromal cells: 49.5;Ependymal cells: 53.1;Epicardial cells: 106.9;Fibro-adipogenic progenitors: 99.6;Leydig cells: 42.0;Migrating cytotrophoblasts: 39.8;Paneth cells: 54.1;Retinal pigment epithelial cells: 59.7" "Cell type enriched" "Detected in many" 4 "choroid plexus epithelial cell: 206.1" "Region enriched" "Detected in many" 5 "choroid plexus: 32.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Skin - Fibroblasts_2" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 36: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 101: Choroid plexus epithelial cells - Ion transport" PKD1L3 ENSG00000277481 "Polycystin 1 like 3, transient receptor potential channel interacting" Q7Z443 16 71929538-72000402 "Essential proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Epicardial cells: 97.8;Oocytes: 179.6;Paneth cells: 85.1;Sertoli cells: 63.7" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Adipose visceral - Mesothelial cells, Pituitary gland - Lactotropes" "Not detected" "Not detected" NA NA "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" PKD2 "Pc-2, PC2, PKD4, TRPP2" ENSG00000118762 "Polycystin 2, transient receptor potential cation channel" Q13563 4 88007635-88077777 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Potassium transport, Transport" "Calcium channel, Ion channel, Potassium channel, Voltage-gated channel" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 106.7" "Cell type enhanced" "Detected in many" "Mesothelial cells: 364.2;Renal collecting duct principal cells: 325.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.4" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004544, HPA015794, HPA055297" Approved Supported "Endoplasmic reticulum,Plasma membrane,Cytosol" "Secreted - unknown location" Transport NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 11: White matter - Signal transduction" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 25 "Endoplasmic reticulum, Plasma membrane" Cytosol "CAB004544: , HPA015794: , HPA055297: " "unprognostic (6.97e-2)" "unprognostic (1.91e-1)" "unprognostic (1.67e-1)" "unprognostic (1.43e-1)" "unprognostic (3.41e-2)" "unprognostic (1.46e-1)" "unprognostic (3.29e-1)" "unprognostic (1.09e-3)" "unprognostic (1.57e-1)" "unprognostic (9.98e-3)" "validated prognostic favorable (1.63e-7)" "validated prognostic favorable (4.33e-4)" "unprognostic (3.04e-3)" "unprognostic (3.83e-2)" "unprognostic (1.01e-1)" "unprognostic (1.49e-1)" "unprognostic (1.07e-2)" "unprognostic (1.15e-1)" "unprognostic (1.69e-1)" "unprognostic (1.13e-1)" "unprognostic (1.56e-2)" "unprognostic (2.18e-1)" "unprognostic (3.11e-1)" "unprognostic (2.07e-1)" "unprognostic (2.24e-2)" "unprognostic (8.06e-3)" "unprognostic (1.42e-1)" "unprognostic (1.00e-2)" "unprognostic (2.72e-1)" "unprognostic (3.37e-2)" "unprognostic (3.27e-1)" PKD2L1 "PCL, PKD2L, PKDL, TRPP3" ENSG00000107593 "Polycystin 2 like 1, transient receptor potential cation channel" Q9P0L9 10 100288149-100330264 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 7.6;retina: 12.3" "Cell type enhanced" "Detected in some" "Early spermatids: 24.3;Hofbauer cells: 16.0;Kupffer cells: 30.7;Late spermatids: 34.8;Podocytes: 16.5;Respiratory ionocytes: 10.2;Retinal horizontal cells: 86.1" "Cell type enhanced" "Detected in some" "deep-layer intratelencephalic: 7.7;deep-layer near-projecting: 19.2" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 5.7" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 2.2;Uterine cancer: 1.0" "Spleen - Macrophages, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB022621, HPA070002" Uncertain Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 53: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 1 "Plasma membrane" "Actin filaments, Cytosol" "CAB022621: , HPA070002: " "unprognostic (9.32e-2)" "unprognostic (2.34e-2)" "unprognostic (1.14e-2)" "unprognostic (9.85e-2)" "unprognostic (8.19e-2)" "unprognostic (2.58e-1)" "potential prognostic favorable (9.09e-5)" "unprognostic (3.75e-1)" "unprognostic (4.65e-2)" "unprognostic (6.03e-2)" "unprognostic (2.44e-2)" "unprognostic (3.23e-1)" "unprognostic (1.18e-1)" "unprognostic (1.08e-1)" "unprognostic (1.57e-2)" PKD2L2 TRPP5 ENSG00000078795 "Polycystin 2 like 2, transient receptor potential cation channel" Q9NZM6 5 137887968-137942747 "Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 7.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 619.7;Epicardial cells: 156.9;Late primary spermatocytes: 185.0;Myonuclei: 88.6" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 5.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA041903, HPA043634" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 57: Testis - Spermatogenesis" "Cluster 34: Non-specific - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" "Plasma membrane" Cytosol "HPA041903: , HPA043634: " "unprognostic (1.74e-1)" "unprognostic (3.92e-2)" "unprognostic (2.11e-3)" "potential prognostic unfavorable (1.36e-4)" "unprognostic (1.78e-1)" "unprognostic (5.91e-2)" "unprognostic (2.89e-2)" "unprognostic (1.78e-1)" "unprognostic (1.16e-2)" "unprognostic (3.46e-1)" "unprognostic (2.31e-1)" PKDCC "SgK493, Vlk" ENSG00000162878 "Protein kinase domain containing, cytoplasmic" Q504Y2 2 42048021-42058517 "Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins" "Differentiation, Osteogenesis, Protein transport, Transport" "Developmental protein, Kinase, Transferase, Tyrosine-protein kinase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 85.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 120.1;Leydig cells: 207.8;Myonuclei: 80.1;Peritubular myoid cells: 176.2;Rod photoreceptor cells: 97.1;Smooth muscle cells: 87.5;Thymic myoid cells: 142.8" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Stomach Adenocarcinoma (TCGA): 35.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 59.6" "Breast - Adipocytes (Breast), Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Fibroblasts, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026427, HPA026442, HPA026526" Approved "Secreted to blood" Transport NA NA 98000 "Cluster 24: Non-specific - Transcription" "Cluster 53: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 94: Gonadal somatic cells - Mixed function" 1 "HPA026427: , HPA026442: , HPA026526: " "unprognostic (3.98e-1)" "unprognostic (1.83e-2)" "unprognostic (1.99e-1)" "unprognostic (9.07e-3)" "unprognostic (5.38e-2)" "unprognostic (7.52e-2)" "unprognostic (6.92e-2)" "unprognostic (5.89e-2)" "unprognostic (3.19e-3)" "unprognostic (2.21e-1)" "unprognostic (3.31e-3)" "unprognostic (1.98e-1)" "unprognostic (1.13e-1)" "potential prognostic unfavorable (1.09e-5)" "unprognostic (1.34e-1)" "unprognostic (1.08e-1)" "unprognostic (1.91e-1)" "unprognostic (2.94e-2)" "unprognostic (4.32e-2)" "unprognostic (5.51e-2)" "unprognostic (1.19e-1)" "unprognostic (4.04e-2)" "unprognostic (1.67e-1)" "unprognostic (1.32e-1)" "unprognostic (6.91e-2)" "unprognostic (1.62e-1)" "unprognostic (1.29e-1)" "unprognostic (1.19e-1)" "unprognostic (3.71e-2)" "unprognostic (3.71e-2)" PKDREJ ENSG00000130943 "Polycystin family receptor for egg jelly" Q9NTG1 22 46255663-46263343 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "testis: 3.2" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 4.4;Cone photoreceptor cells: 2.1;Early primary spermatocytes: 4.3;Early spermatids: 2.2;Late primary spermatocytes: 12.8;Late spermatids: 1.5;Retinal horizontal cells: 2.0;Retinal pigment epithelial cells: 4.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Not detected" "Not detected" HPA034587 Enhanced NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" "HPA034587: " "unprognostic (3.84e-1)" PKHD1 "ARPKD, FCYT, FPC, TIGM1" ENSG00000170927 "PKHD1 ciliary IPT domain containing fibrocystin/polyductin" P08F94 6 51615299-52087613 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "epididymis: 4.5;kidney: 12.7;pancreas: 8.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 991.3;Distal convoluted tubule cells: 3139.1;Loop of henle epithelial cells: 2248.0;Pancreatic duct cells: 963.9;Papillary tip epithelial cells: 1061.1;Proximal tubule cells: 3459.8;Renal collecting duct intercalated cells: 633.6;Renal collecting duct principal cells: 2022.9;Renal connecting tubule cells: 2968.5" "Cell type enhanced" "Detected in many" "thalamic excitatory: 8.7" "Group enriched" "Detected in some" 5 "Kidney Renal Clear Cell Carcinoma (TCGA): 5.9;Kidney Renal Papillary Cell Carcinoma (TCGA): 12.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 2.1;Kidney cancer: 2.0" "Adrenal gland - Adrenal medulla cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA031227, HPA031229" Enhanced Supported "Primary cilium,Basal body,Cytosol" "Intracellular and membrane" Receptor NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 15: Kidney cancer - Membrane components" "Cluster 88: Proximal tubular cells - Transmembrane transport" 1 "Primary cilium, Cytosol" "Basal body" "HPA031227: , HPA031229: " "potential prognostic favorable (1.63e-8)" "unprognostic (3.13e-3)" "unprognostic (4.04e-3)" "unprognostic (1.41e-2)" "unprognostic (7.56e-3)" "unprognostic (3.46e-3)" PKHD1L1 ENSG00000205038 "PKHD1 like 1" Q86WI1 8 109362461-109537207 "Predicted membrane proteins" Receptor "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 22.1;thyroid gland: 61.4" "Group enriched" "Detected in many" 4 "Epicardial cells: 1237.1;Lymphatic endothelial cells: 1442.4;Mesothelial cells: 1321.7;Platelets: 503.5" "Cell type enriched" "Detected in some" 27 "endothelial cell: 89.7" "Group enriched" "Detected in some" 15 "Ovary Serous Cystadenocarcinoma (TCGA): 4.7;Thyroid Carcinoma (TCGA): 12.0;Uterine Corpus Endometrial Carcinoma (TCGA): 14.6" "Region enhanced" "Detected in single" "choroid plexus: 3.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lymphoma: 1.1" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Skeletal muscle - Smooth muscle cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA044458 Uncertain Approved "Flagellar centriole,Mid piece,Principal piece" NA NA 16000000 "Cluster 33: Thyroid gland - Tissue development" "Cluster 36: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "Flagellar centriole, Mid piece, Principal piece" "HPA044458: " "unprognostic (1.60e-1)" "unprognostic (2.32e-3)" "unprognostic (1.84e-3)" "unprognostic (9.95e-2)" PKIA PRKACN1 ENSG00000171033 "CAMP-dependent protein kinase inhibitor alpha" P61925 8 78516340-78605267 "Predicted intracellular proteins" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "skeletal muscle: 1087.6;tongue: 889.8" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 138.3;Brain excitatory neurons: 144.1;Brain inhibitory neurons: 174.5;Lactotrophs: 202.5;Myonuclei: 269.2;Other brain neurons: 137.3;Retinal amacrine cells: 164.8;Retinal horizontal cells: 150.3;Somatotrophs: 188.9;Thymic myoid cells: 157.7" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 42.4;Kidney Chromophobe (TCGA): 46.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 21.5" "Lineage enriched" "Detected in many" 9 "T-cells: 21.5" "Cancer enhanced" "Detected in many" "Neuroblastoma: 43.0" "Adrenal gland - Adrenal medulla cells, Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Spleen - B-cells (Spleen), Stomach - Fibroblasts, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042791 Uncertain NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 33: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 9: T-cells - Adaptive immunity: Regulation" 11 "HPA042791: " "unprognostic (1.79e-3)" "unprognostic (5.91e-3)" "unprognostic (6.46e-2)" "unprognostic (5.70e-2)" "unprognostic (1.71e-1)" "unprognostic (6.63e-3)" "unprognostic (1.02e-1)" "unprognostic (5.20e-3)" "unprognostic (5.78e-2)" "unprognostic (6.92e-2)" "unprognostic (4.59e-2)" "unprognostic (1.42e-2)" "unprognostic (1.73e-1)" "unprognostic (1.72e-2)" "unprognostic (6.93e-2)" "unprognostic (2.33e-2)" "unprognostic (1.06e-1)" "unprognostic (2.53e-1)" "unprognostic (1.60e-1)" "unprognostic (1.27e-1)" "unprognostic (9.90e-3)" "unprognostic (1.52e-1)" "unprognostic (1.13e-1)" "unprognostic (2.30e-3)" "unprognostic (9.03e-3)" "unprognostic (1.37e-2)" "unprognostic (2.57e-1)" "unprognostic (2.02e-1)" "unprognostic (6.15e-2)" PKIB PRKACN2 ENSG00000135549 "CAMP-dependent protein kinase inhibitor beta" Q9C010 6 122471917-122726373 "Predicted intracellular proteins" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 248.3;intestine: 87.1" "Cell type enhanced" "Detected in many" "Colonocytes: 900.5;Cytotrophoblasts: 810.5;Enterocytes: 386.7;Extravillous trophoblasts: 555.1;Foveolar cells: 281.0;Late spermatids: 437.8;Migrating cytotrophoblasts: 626.6;Syncytiotrophoblasts: 1108.2" "Cell type enhanced" "Detected in all" "lower rhombic lip: 159.7;midbrain-derived inhibitory: 154.7;upper rhombic lip: 374.0" "Cancer enhanced" "Detected in all" "Breast Invasive Carcinoma (TCGA): 78.1" "Region enriched" "Detected in all" 5 "cerebellum: 146.1" "Immune cell enriched" "Detected in some" 10 "myeloid DC: 34.9" "Lineage enriched" "Detected in many" 10 "dendritic cells: 34.9" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Pituitary gland - Somatotropes, Testis - Late spermatids" "Region enhanced" "Detected in all" "cerebellum: 63.0" "Group enriched" "Detected in all" 4 "cerebellum: 66.6;olfactory bulb: 37.5" HPA030156 Approved NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 27: Cerebellum - Synaptic function" "Cluster 35: Non-specific - DNA binding" "Cluster 11: Neuronal - Sensory perception" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" "HPA030156: " "unprognostic (1.69e-3)" "unprognostic (8.71e-2)" "unprognostic (1.27e-1)" "unprognostic (1.70e-1)" "unprognostic (1.12e-1)" "unprognostic (2.60e-1)" "unprognostic (1.21e-1)" "unprognostic (1.24e-2)" "unprognostic (1.48e-1)" "unprognostic (9.29e-2)" "unprognostic (8.69e-3)" "unprognostic (2.69e-1)" "unprognostic (1.17e-3)" "validated prognostic unfavorable (5.91e-8)" "validated prognostic unfavorable (2.06e-6)" "potential prognostic unfavorable (5.26e-4)" "unprognostic (5.22e-2)" "unprognostic (5.41e-2)" "unprognostic (2.22e-3)" "unprognostic (1.17e-2)" "unprognostic (4.59e-2)" "unprognostic (1.75e-1)" "potential prognostic unfavorable (5.91e-5)" "unprognostic (2.34e-2)" "unprognostic (1.28e-3)" "unprognostic (5.33e-2)" "unprognostic (6.73e-2)" "unprognostic (7.47e-2)" "unprognostic (1.22e-1)" "unprognostic (9.51e-2)" "unprognostic (2.76e-2)" PKIG ENSG00000168734 "CAMP-dependent protein kinase inhibitor gamma" Q9Y2B9 20 44531785-44624247 "Predicted intracellular proteins" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 366.9;Megakaryocyte-Erythroid progenitors: 400.4;Smooth muscle cells: 334.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "memory B-cell: 371.9;naive B-cell: 378.7" "Lineage enriched" "Detected in all" 11 "B-cells: 378.7" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Cardiomyocytes, Minor Salivary Gland - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042703, HPA063690" Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" No No "Cluster 18: Non-specific - Translation" "Cluster 35: Non-specific - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 55: Lymphoma - Immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 6 "Nucleoplasm, Cytosol" "Vesicles, Plasma membrane" "HPA042703: , HPA063690: " "unprognostic (7.22e-3)" "unprognostic (2.55e-1)" "unprognostic (3.39e-2)" "unprognostic (1.35e-1)" "unprognostic (1.89e-1)" "unprognostic (5.21e-2)" "unprognostic (7.30e-2)" "unprognostic (3.81e-1)" "unprognostic (5.89e-2)" "unprognostic (8.69e-2)" "validated prognostic favorable (6.07e-6)" "validated prognostic favorable (1.21e-4)" "potential prognostic favorable (2.69e-4)" "unprognostic (4.38e-3)" "unprognostic (5.40e-2)" "unprognostic (1.56e-2)" "unprognostic (1.94e-1)" "unprognostic (1.02e-3)" "unprognostic (1.55e-1)" "unprognostic (1.43e-1)" "unprognostic (5.04e-3)" "unprognostic (1.40e-3)" "unprognostic (2.07e-1)" "unprognostic (1.27e-1)" "unprognostic (2.89e-1)" "unprognostic (1.27e-2)" "unprognostic (2.06e-1)" "unprognostic (5.25e-3)" "unprognostic (2.25e-1)" "unprognostic (2.16e-1)" "unprognostic (4.03e-2)" PKLR ENSG00000143627 "Pyruvate kinase L/R" P30613 1 155289293-155301438 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Disease variant, FDA approved drug targets, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 18.4;kidney: 23.5;liver: 86.5" "Group enriched" "Detected in some" 5 "Erythrocyte progenitors: 8.9;Late spermatids: 7.0;Proximal tubule cells: 11.3" "Low cell type specificity" "Detected in some" "Cancer enriched" "Detected in many" 7 "Liver Hepatocellular Carcinoma (TCGA): 70.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 7.2;skin cancer: 2.9" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Sebaceous gland cells, Testis - Late spermatids" "Region enhanced" "Detected in single" "basal ganglia: 1.6" "Low region specificity" "Detected in all" "HPA006653, CAB034376, CAB034378" Enhanced Approved Cytosol No NA 8800000 "Cluster 16: Liver & Kidney - Metabolism" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 47: Leukemia - Hemostasis" "Cluster 88: Proximal tubular cells - Transmembrane transport" 2 Cytosol "CAB034376: , CAB034378: , HPA006653: " "unprognostic (1.96e-1)" "potential prognostic favorable (7.04e-7)" "unprognostic (7.94e-3)" "unprognostic (2.73e-3)" "unprognostic (5.53e-2)" "unprognostic (2.20e-2)" "unprognostic (2.82e-2)" "unprognostic (2.30e-1)" "unprognostic (2.04e-1)" "unprognostic (1.14e-1)" PKM "OIP3, PK3, PKM2, THBP1" ENSG00000067225 "Pyruvate kinase M1/2" P14618 15 72199029-72231819 "Cancer-related genes, Enzymes, Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glycolysis, Translation regulation" "Allosteric enzyme, Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 3777.5;tongue: 2492.1" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1306.9;Esophageal basal cells: 1726.6;Esophageal suprabasal cells: 1757.1;Extravillous trophoblasts: 1864.4;Late spermatids: 3109.8;Platelets: 1678.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells, Skeletal muscle - Skeletal myocytes, Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019421, HPA029501" Uncertain Enhanced "Vesicles,Cytosol,Principal piece" No No 260000000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 82 Cytosol "Vesicles, Principal piece" "CAB019421: , HPA029501: " "unprognostic (2.42e-2)" "unprognostic (1.27e-2)" "unprognostic (1.64e-2)" "unprognostic (9.33e-2)" "unprognostic (2.65e-2)" "unprognostic (8.85e-3)" "unprognostic (3.85e-2)" "potential prognostic unfavorable (1.06e-4)" "unprognostic (1.14e-2)" "unprognostic (2.51e-2)" "unprognostic (1.17e-1)" "unprognostic (2.18e-1)" "potential prognostic unfavorable (7.67e-6)" "validated prognostic unfavorable (3.97e-6)" "validated prognostic unfavorable (1.98e-6)" "unprognostic (1.33e-1)" "unprognostic (1.85e-2)" "unprognostic (3.64e-2)" "unprognostic (3.64e-1)" "potential prognostic unfavorable (1.28e-4)" "unprognostic (1.74e-2)" "unprognostic (1.35e-1)" "unprognostic (1.07e-1)" "unprognostic (1.30e-1)" "unprognostic (1.06e-1)" "unprognostic (4.06e-2)" "unprognostic (2.30e-1)" "unprognostic (3.18e-1)" "unprognostic (1.40e-3)" PKMYT1 "MYT1, PPP1R126" ENSG00000127564 "Protein kinase, membrane associated tyrosine/threonine 1" Q99640 16 2968024-2980479 "Enzymes, Essential proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 26.1;testis: 57.6" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 32.7;Early primary spermatocytes: 125.7;Enteric transient amplifying cells: 20.1;Erythrocyte progenitors: 40.3;Esophageal basal cells: 24.1;Extravillous trophoblasts: 62.6;Late primary spermatocytes: 69.6;Megakaryocyte progenitors: 24.9;Migrating cytotrophoblasts: 32.8;Monocyte progenitors: 26.5;Oocytes: 23.0;Paneth cells: 19.3" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 6 "T-reg: 1.3" "Lineage enriched" "Detected in single" 6 "T-cells: 1.3" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA068860 Supported "Nucleoplasm,Nucleoli,Golgi apparatus" NA Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 39: Testis - Nuclear processes" "Cluster 6: Non-specific - Immune response" "Cluster 54: Non-specific - Transcription" "Cluster 27: Non-specific - Cell proliferation" 48 "Golgi apparatus" "Nucleoplasm, Nucleoli" "HPA068860: " "unprognostic (2.33e-1)" "unprognostic (1.01e-1)" "unprognostic (4.01e-1)" "unprognostic (7.01e-3)" "unprognostic (1.19e-1)" "unprognostic (2.12e-1)" "unprognostic (2.00e-2)" "unprognostic (7.01e-3)" "unprognostic (7.40e-2)" "potential prognostic unfavorable (2.63e-4)" "validated prognostic unfavorable (2.32e-9)" "validated prognostic unfavorable (5.09e-5)" "potential prognostic unfavorable (1.57e-5)" "validated prognostic unfavorable (3.35e-4)" "validated prognostic unfavorable (3.71e-6)" "potential prognostic unfavorable (3.36e-7)" "unprognostic (4.86e-2)" "unprognostic (2.37e-1)" "unprognostic (3.29e-1)" "unprognostic (4.65e-2)" "unprognostic (6.55e-3)" "unprognostic (3.81e-3)" "unprognostic (1.42e-2)" "unprognostic (8.27e-2)" "unprognostic (3.48e-1)" "unprognostic (1.71e-1)" "unprognostic (2.92e-2)" "unprognostic (1.47e-3)" "unprognostic (1.11e-1)" "unprognostic (3.91e-2)" "unprognostic (7.01e-2)" PKN1 "DBK, MGC46204, PAK1, PKN, PRK1, PRKCL1" ENSG00000123143 "Protein kinase N1" Q16512 19 14433053-14471867 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003982, CAB010278" Approved Approved "Plasma membrane,Cytokinetic bridge" Yes NA "Cluster 25: Non-specific - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 44: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 89 "Plasma membrane" "Cytokinetic bridge" "CAB010278: , HPA003982: " "unprognostic (4.50e-2)" "unprognostic (1.65e-1)" "unprognostic (2.68e-1)" "unprognostic (2.07e-1)" "unprognostic (9.61e-3)" "unprognostic (1.24e-1)" "unprognostic (1.03e-1)" "unprognostic (6.56e-2)" "unprognostic (4.24e-1)" "unprognostic (1.65e-2)" "potential prognostic favorable (7.65e-4)" "unprognostic (3.79e-1)" "unprognostic (2.14e-1)" "unprognostic (1.01e-2)" "potential prognostic unfavorable (2.70e-5)" "unprognostic (4.76e-2)" "unprognostic (1.36e-1)" "unprognostic (2.15e-1)" "unprognostic (2.58e-1)" "unprognostic (1.01e-2)" "unprognostic (1.25e-2)" "unprognostic (3.15e-2)" "unprognostic (5.45e-2)" "unprognostic (5.65e-2)" "unprognostic (1.22e-1)" "unprognostic (8.86e-3)" "unprognostic (1.56e-1)" "unprognostic (6.17e-2)" "unprognostic (1.40e-1)" "unprognostic (8.50e-2)" "unprognostic (1.15e-1)" PKN2 "Pak-2, PRK2, PRKCL2, STK7" ENSG00000065243 "Protein kinase N2" Q16513 1 88684222-88836255 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell adhesion, Cell cycle, Cell division, Cilium biogenesis/degradation, Host-virus interaction, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 827.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "neutrophil: 80.7" "Lineage enriched" "Detected in all" 8 "granulocytes: 80.7" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034861, HPA057913" Approved Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Intermediate filaments,Centrosome,Cytosol" Yes No "Cluster 21: Neutrophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 24: Neutrophils - Innate immunity signal integration" 41 "Nucleoplasm, Intermediate filaments" "Nuclear bodies, Plasma membrane, Centrosome, Cytosol" "HPA034861: , HPA057913: " "unprognostic (1.10e-1)" "unprognostic (1.56e-1)" "unprognostic (2.23e-2)" "unprognostic (3.71e-2)" "unprognostic (3.50e-3)" "unprognostic (3.51e-2)" "unprognostic (4.49e-2)" "unprognostic (2.46e-1)" "unprognostic (2.27e-2)" "potential prognostic unfavorable (2.46e-4)" "validated prognostic favorable (1.43e-5)" "validated prognostic favorable (8.91e-5)" "unprognostic (3.46e-2)" "unprognostic (1.37e-3)" "unprognostic (1.55e-1)" "unprognostic (2.23e-2)" "unprognostic (3.38e-2)" "unprognostic (3.06e-1)" "unprognostic (2.23e-2)" "unprognostic (3.23e-1)" "unprognostic (1.63e-1)" "unprognostic (1.85e-3)" "unprognostic (1.56e-2)" "unprognostic (2.18e-1)" "unprognostic (1.31e-2)" "unprognostic (4.42e-2)" "unprognostic (1.00e-1)" "unprognostic (1.03e-1)" "unprognostic (3.40e-1)" "unprognostic (3.62e-2)" "unprognostic (7.91e-3)" PKN3 "PKNbeta, UTDP4-1" ENSG00000160447 "Protein kinase N3" Q6P5Z2 9 128702503-128720916 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast lactating cells: 148.7;Lymphatic endothelial cells: 37.5;Respiratory deuterosomal cells: 23.8;Vascular endothelial cells: 60.6" "Cell type enriched" "Detected in some" 7 "endothelial cell: 61.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA045390, HPA058305" Uncertain Approved Vesicles NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 25: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 20 Vesicles "HPA045390: , HPA058305: " "unprognostic (2.23e-2)" "unprognostic (5.73e-2)" "unprognostic (1.70e-1)" "unprognostic (1.97e-2)" "unprognostic (1.28e-1)" "unprognostic (5.32e-3)" "unprognostic (1.13e-1)" "unprognostic (4.15e-1)" "unprognostic (4.03e-2)" "unprognostic (1.14e-1)" "unprognostic (7.14e-3)" "unprognostic (1.22e-2)" "unprognostic (1.47e-1)" "unprognostic (6.04e-2)" "unprognostic (1.75e-3)" "unprognostic (1.06e-1)" "unprognostic (3.11e-3)" "unprognostic (4.83e-2)" "unprognostic (1.98e-2)" "unprognostic (1.47e-1)" "unprognostic (2.32e-1)" "unprognostic (7.71e-2)" "unprognostic (2.94e-2)" "unprognostic (1.52e-1)" "unprognostic (2.70e-1)" "unprognostic (3.35e-2)" "unprognostic (6.99e-2)" "unprognostic (2.27e-2)" "unprognostic (3.99e-2)" "unprognostic (1.79e-1)" "unprognostic (1.07e-1)" PKNOX1 PREP1 ENSG00000160199 "PBX/knotted 1 homeobox 1" P55347 21 42974510-43033931 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 191.7;Neutrophils: 191.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004285, HPA057215, HPA065017" Approved Approved Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 67: Testis - Mixed function" "Cluster 25: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 20: Non-specific - Transcription regulation" 26 Nucleoplasm "CAB004285: , HPA057215: , HPA065017: " "unprognostic (4.21e-2)" "unprognostic (3.24e-3)" "unprognostic (2.25e-2)" "unprognostic (3.04e-1)" "unprognostic (6.00e-2)" "unprognostic (1.33e-1)" "unprognostic (3.06e-2)" "unprognostic (2.57e-2)" "unprognostic (2.26e-1)" "unprognostic (3.74e-3)" "unprognostic (1.62e-3)" "unprognostic (5.73e-2)" "unprognostic (1.77e-1)" "potential prognostic unfavorable (6.87e-7)" "unprognostic (2.28e-1)" "unprognostic (9.41e-3)" "unprognostic (1.41e-2)" "unprognostic (2.06e-2)" "unprognostic (1.16e-2)" "unprognostic (1.73e-2)" "unprognostic (3.77e-2)" "unprognostic (3.96e-2)" "unprognostic (5.41e-2)" "unprognostic (2.87e-1)" "unprognostic (1.15e-1)" "unprognostic (3.67e-1)" "unprognostic (6.43e-2)" "unprognostic (2.98e-1)" "unprognostic (3.35e-1)" "unprognostic (4.51e-2)" "unprognostic (4.78e-2)" PKNOX2 ENSG00000165495 "PBX/knotted 1 homeobox 2" Q96KN3 11 125164687-125433389 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 33.9" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 356.9;Lactotrophs: 175.6;Melanocytes: 181.5;Myonuclei: 127.6;Myosatellite cells: 175.2;Oligodendrocyte progenitor cells: 135.4;Peritubular myoid cells: 109.5;Pituitary stem cells: 111.1;Prostatic glandular cells: 127.9;Retinal pigment epithelial cells: 225.9;Thymic myoid cells: 225.7;Thyrotrophs: 182.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 26.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bone cancer: 5.5;Sarcoma: 10.0;skin cancer: 11.0;testis cancer: 5.6" "Colon - Enteric glia cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028867, CAB034342, HPA055368, HPA066962" Supported Enhanced "Nucleoplasm,Cytokinetic bridge" Yes NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 53: Neurons - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 32 Nucleoplasm "Cytokinetic bridge" "CAB034342: , HPA028867: , HPA055368: , HPA066962: " "unprognostic (6.00e-2)" "unprognostic (1.55e-1)" "unprognostic (4.05e-2)" "unprognostic (2.22e-3)" "unprognostic (7.34e-3)" "unprognostic (1.12e-1)" "potential prognostic unfavorable (7.00e-4)" "unprognostic (2.37e-1)" "unprognostic (8.94e-2)" "unprognostic (5.58e-2)" "unprognostic (8.99e-2)" "unprognostic (3.66e-2)" "unprognostic (2.14e-1)" "unprognostic (5.96e-2)" "unprognostic (1.40e-1)" "unprognostic (8.88e-3)" "unprognostic (1.95e-1)" PKP1 B6P ENSG00000081277 "Plakophilin 1" Q13835 1 201283452-201332993 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Developmental protein, DNA-binding, RNA-binding" "Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 404.9;skin 1: 665.0;vagina: 192.1" "Group enriched" "Detected in many" 6 "Basal keratinocytes: 307.7;Esophageal apical cells: 705.4;Esophageal basal cells: 402.7;Esophageal suprabasal cells: 962.1;Ocular epithelial cells: 286.2;Suprabasal keratinocytes: 807.3" "Cell type enhanced" "Detected in some" "eccentric medium spiny neuron: 1.5;splatter: 1.8" "Group enriched" "Detected in many" 4 "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 233.7;Head and Neck Squamous Cell Carcinoma (TCGA): 464.1;Lung Squamous Cell Carcinoma (TCGA): 237.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 160.4;Esophageal cancer: 70.1;head and neck cancer: 89.8" "Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Prostate glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA027221, CAB033130" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 2700000 "Cluster 58: Skin - Keratinization" "Cluster 53: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 85: Squamous epithelial cells - Keratinization" 10 "Nucleoplasm, Plasma membrane" "CAB033130: , HPA027221: " "unprognostic (9.92e-2)" "unprognostic (5.24e-3)" "unprognostic (2.04e-1)" "unprognostic (1.64e-1)" "unprognostic (6.48e-2)" "unprognostic (1.18e-1)" "unprognostic (1.17e-1)" "unprognostic (4.20e-3)" "unprognostic (3.42e-2)" "unprognostic (1.88e-2)" "unprognostic (4.19e-3)" "unprognostic (4.03e-1)" "unprognostic (8.02e-3)" "unprognostic (1.84e-1)" "unprognostic (1.33e-3)" "potential prognostic unfavorable (1.82e-6)" "unprognostic (1.19e-1)" "unprognostic (2.02e-1)" "unprognostic (3.82e-1)" "unprognostic (1.18e-1)" "unprognostic (1.53e-2)" "unprognostic (2.09e-1)" "unprognostic (1.33e-1)" "unprognostic (8.09e-3)" PKP2 ENSG00000057294 "Plakophilin 2" Q99959 12 32790745-32896777 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 185.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 661.1;Epididymal clear cells: 263.3;Extravillous trophoblasts: 408.4;Fallopian tube ciliated cells: 346.0;Lacrimal acinar cells: 489.1;Salivary acinar cells: 278.0;Salivary basal cells: 268.1;Salivary ionocytes: 618.5" "Group enriched" "Detected in many" 4 "CGE interneuron: 136.5;fibroblast: 159.9;hippocampal CA1-3: 52.8;hippocampal CA4: 66.0;LAMP5-LHX6 and Chandelier: 179.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 5.6;eosinophil: 6.9;myeloid DC: 2.7" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "testis cancer: 164.7" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Prostate - Prostate basal glandular cells" "Region enriched" "Detected in many" 4 "hippocampal formation: 20.2" "Low region specificity" "Detected in all" "HPA014314, CAB037336, HPA056908" Enhanced Enhanced "Nucleoplasm,Cell Junctions" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 35: Non-specific - Mixed function" "Cluster 29: Forebrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 41 "Cell Junctions" Nucleoplasm "CAB037336: , HPA014314: , HPA056908: " "unprognostic (9.77e-2)" "unprognostic (4.13e-1)" "unprognostic (2.45e-1)" "unprognostic (1.51e-2)" "unprognostic (1.45e-2)" "unprognostic (7.36e-2)" "unprognostic (5.39e-3)" "unprognostic (5.62e-2)" "potential prognostic unfavorable (7.45e-4)" "potential prognostic favorable (1.56e-7)" "unprognostic (1.13e-1)" "unprognostic (1.28e-2)" "unprognostic (7.17e-2)" "unprognostic (2.39e-1)" "potential prognostic unfavorable (1.01e-6)" "unprognostic (2.81e-2)" "unprognostic (2.03e-1)" "unprognostic (2.06e-1)" "unprognostic (2.02e-1)" "unprognostic (1.89e-1)" "unprognostic (7.85e-3)" "unprognostic (1.51e-1)" "unprognostic (1.41e-1)" "unprognostic (1.32e-2)" "unprognostic (3.13e-2)" "unprognostic (8.97e-2)" "unprognostic (2.70e-2)" "unprognostic (9.39e-2)" "unprognostic (1.26e-1)" PKP3 ENSG00000184363 "Plakophilin 3" Q9Y446 11 392614-404908 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 283.5;skin 1: 212.8" "Cell type enhanced" "Detected in many" "Colonocytes: 249.2;Enterocytes: 182.8;Esophageal apical cells: 1282.3;Esophageal basal cells: 314.4;Esophageal suprabasal cells: 736.9;Extravillous trophoblasts: 239.4;Migrating cytotrophoblasts: 167.2;Suprabasal keratinocytes: 289.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Pituitary gland - Corticotropes" "Region enriched" "Detected in single" 37 "cerebellum: 8.9" "Low region specificity" "Detected in all" "CAB012993, HPA062937" Enhanced Enhanced "Nucleoplasm,Cell Junctions" NA NA 5700 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 24: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 19 "Cell Junctions" Nucleoplasm "CAB012993: , HPA062937: " "unprognostic (7.27e-3)" "unprognostic (6.36e-2)" "unprognostic (1.46e-2)" "unprognostic (5.92e-2)" "unprognostic (1.78e-1)" "unprognostic (1.08e-1)" "unprognostic (2.15e-1)" "unprognostic (7.99e-2)" "validated prognostic unfavorable (3.40e-9)" "validated prognostic unfavorable (7.04e-4)" "unprognostic (3.64e-1)" "unprognostic (2.28e-2)" "unprognostic (2.28e-2)" "unprognostic (3.81e-3)" "unprognostic (5.78e-3)" "potential prognostic unfavorable (9.74e-4)" "unprognostic (1.96e-1)" "unprognostic (2.24e-3)" "unprognostic (4.00e-1)" "unprognostic (1.19e-3)" "unprognostic (1.73e-2)" "unprognostic (2.65e-2)" "unprognostic (3.39e-1)" "unprognostic (3.64e-2)" "unprognostic (1.33e-1)" "unprognostic (2.18e-2)" "unprognostic (4.86e-1)" "unprognostic (8.92e-2)" "unprognostic (2.73e-1)" PKP4 p0071 ENSG00000144283 "Plakophilin 4" Q99569 2 158456952-158682879 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "brain: 336.1" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 1480.6;Loop of henle epithelial cells: 1143.2;Oligodendrocytes: 1268.3" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 2317.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 2.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037334, HPA066647, HPA070648" Approved Enhanced "Plasma membrane,Cell Junctions" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 72: Neuronal - Signal transduction" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 23 "Cell Junctions" "Plasma membrane" "CAB037334: , HPA066647: , HPA070648: " "unprognostic (4.08e-1)" "unprognostic (8.68e-2)" "unprognostic (2.15e-1)" "unprognostic (5.35e-2)" "unprognostic (1.53e-1)" "unprognostic (5.15e-2)" "unprognostic (1.04e-1)" "unprognostic (2.86e-2)" "unprognostic (1.79e-1)" "unprognostic (1.31e-1)" "validated prognostic favorable (1.39e-9)" "validated prognostic favorable (2.74e-4)" "unprognostic (5.43e-2)" "unprognostic (2.26e-2)" "unprognostic (2.81e-2)" "unprognostic (1.93e-2)" "unprognostic (1.32e-1)" "unprognostic (1.54e-1)" "unprognostic (1.78e-2)" "unprognostic (2.18e-1)" "unprognostic (1.22e-1)" "unprognostic (5.53e-3)" "unprognostic (1.83e-1)" "unprognostic (2.17e-1)" "unprognostic (2.33e-2)" "unprognostic (9.89e-2)" "unprognostic (1.48e-1)" "unprognostic (1.70e-1)" "unprognostic (1.48e-1)" "unprognostic (3.42e-2)" "unprognostic (6.76e-2)" PLA1A ps-PLA1 ENSG00000144837 "Phospholipase A1 member A" Q53H76 3 119597875-119629811 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 85.7;epididymis: 130.6;parathyroid gland: 62.0;seminal vesicle: 63.3" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 58.2;Epididymal efferent duct absorptive cells: 91.5;Epididymal efferent duct ciliated cells: 29.4;Epididymal principal cells: 102.3;Hepatocytes: 37.7;Lymphatic endothelial cells: 24.5;Retinal pigment epithelial cells: 29.8;Thymic myoid cells: 81.6;Vascular endothelial cells: 28.9" "Group enriched" "Detected in some" 16 "choroid plexus epithelial cell: 55.8;endothelial cell: 78.6" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 120.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 22.8;skin cancer: 34.7" "Breast - Endothelial cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted in other tissues" Enzyme NA NA 190000 "Cluster 22: Epididymis - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" "unprognostic (3.96e-2)" "unprognostic (7.17e-2)" "unprognostic (4.32e-1)" "potential prognostic favorable (1.24e-5)" "unprognostic (7.98e-3)" "unprognostic (9.86e-3)" "unprognostic (1.36e-1)" "unprognostic (1.01e-2)" "unprognostic (4.75e-2)" "unprognostic (1.50e-1)" "unprognostic (5.06e-2)" "unprognostic (4.72e-3)" "unprognostic (6.67e-3)" "unprognostic (1.61e-2)" "unprognostic (4.33e-2)" "unprognostic (1.05e-1)" "unprognostic (5.39e-2)" "unprognostic (7.84e-2)" "unprognostic (1.29e-1)" "unprognostic (3.31e-2)" "unprognostic (4.30e-2)" "unprognostic (3.55e-3)" "unprognostic (9.08e-2)" "unprognostic (1.97e-1)" "unprognostic (4.32e-2)" "unprognostic (2.63e-1)" "unprognostic (4.77e-3)" "unprognostic (2.19e-2)" "unprognostic (2.35e-1)" "unprognostic (1.14e-2)" PLA2G10 GXPLA2 ENSG00000069764 "Phospholipase A2 group X" O15496 16 14672548-14694308 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted secreted proteins, RAS pathway related proteins" "Lipid metabolism, Phospholipid metabolism" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 25.4;stomach 1: 39.5" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 29.1;Colonocytes: 150.9;Endometrial luminal cells: 44.5;Enteric transient amplifying cells: 24.6;Extravillous trophoblasts: 68.0;Foveolar cells: 89.6;Gastric progenitor cells: 61.5;Goblet cells: 111.9;Prostatic club cells: 31.3;Transitional alveolar cells: 25.9" "Low cell type specificity" "Detected in some" "Group enriched" "Detected in many" 6 "Colon Adenocarcinoma (TCGA): 18.7;Lung Adenocarcinoma (TCGA): 46.2;Pancreatic Adenocarcinoma (TCGA): 42.7;Rectum Adenocarcinoma (TCGA): 20.1;Stomach Adenocarcinoma (TCGA): 33.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 6.0;Gastric cancer: 4.1;pancreatic cancer: 4.4" "Colon - Colon enterocytes, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA041893 Uncertain "Secreted in other tissues" Enzyme NA NA "Cluster 17: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 42 "HPA041893: " "unprognostic (3.98e-2)" "unprognostic (1.45e-2)" "unprognostic (4.29e-2)" "unprognostic (9.33e-2)" "unprognostic (3.73e-2)" "unprognostic (2.28e-1)" "unprognostic (5.96e-2)" "unprognostic (4.65e-2)" "unprognostic (2.24e-2)" "unprognostic (3.44e-2)" "unprognostic (3.81e-1)" "unprognostic (7.78e-2)" "unprognostic (1.37e-3)" "unprognostic (2.67e-1)" "unprognostic (2.51e-2)" "unprognostic (3.12e-2)" "unprognostic (6.39e-3)" "unprognostic (1.95e-1)" "unprognostic (3.97e-2)" "unprognostic (2.51e-1)" PLA2G12A PLA2G12 ENSG00000123739 "Phospholipase A2 group XIIA" Q9BZM1 4 109709989-109730070 "Enzymes, Metabolic proteins, Predicted secreted proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Platelets: 499.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035908, HPA035909" Approved "Secreted to blood" Enzyme NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 47: Platelets - Hemostasis" 3 "HPA035908: , HPA035909: " "unprognostic (3.95e-2)" "unprognostic (1.84e-2)" "unprognostic (5.47e-2)" "unprognostic (9.98e-2)" "unprognostic (3.13e-2)" "unprognostic (1.03e-1)" "unprognostic (2.89e-1)" "unprognostic (5.91e-2)" "unprognostic (1.77e-2)" "unprognostic (7.13e-3)" "validated prognostic favorable (1.39e-4)" "validated prognostic favorable (3.69e-6)" "unprognostic (5.63e-2)" "unprognostic (2.28e-1)" "unprognostic (7.12e-2)" "unprognostic (4.51e-2)" "unprognostic (9.62e-2)" "unprognostic (1.44e-1)" "unprognostic (6.36e-2)" "unprognostic (1.25e-2)" "unprognostic (2.20e-2)" "unprognostic (2.79e-1)" "unprognostic (5.02e-1)" "unprognostic (2.70e-2)" "potential prognostic favorable (7.39e-4)" "unprognostic (8.65e-2)" "unprognostic (3.63e-2)" "unprognostic (1.33e-1)" "unprognostic (2.00e-1)" "unprognostic (4.31e-2)" "unprognostic (8.73e-2)" PLA2G12B PLA2G13 ENSG00000138308 "Phospholipase A2 group XIIB" Q9BX93 10 72934762-72954806 "Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 31.1;kidney: 13.4;liver: 66.4" "Group enriched" "Detected in some" 4 "Enterocytes: 121.2;Hepatocytes: 74.0" "Cell type enhanced" "Detected in single" "hippocampal CA4: 1.3" "Cancer enriched" "Detected in many" 6 "Liver Hepatocellular Carcinoma (TCGA): 33.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "liver cancer: 7.1" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA057745, HPA059562" Approved "Secreted to blood" "No annotated function" NA NA 220000 "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 1: Neuronal - Visual perception" "Cluster 1: Enterocytes - Absorption and Digestion" "HPA057745: , HPA059562: " "unprognostic (1.01e-1)" "unprognostic (1.19e-1)" "potential prognostic favorable (1.36e-4)" "unprognostic (2.28e-2)" "unprognostic (2.27e-1)" "unprognostic (2.31e-2)" "unprognostic (7.00e-2)" "unprognostic (3.94e-3)" "unprognostic (1.23e-1)" "unprognostic (2.67e-2)" "unprognostic (3.75e-2)" "unprognostic (2.66e-1)" "unprognostic (2.64e-1)" "unprognostic (6.05e-2)" PLA2G15 "GXVPLA2, LLPL, LYPLA3" ENSG00000103066 "Phospholipase A2 group XV" Q8NCC3 16 68245304-68261058 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid degradation, Lipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 56.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 205.4;Kupffer cells: 85.1;Macrophages: 47.9;Microglia: 63.6;Syncytiotrophoblasts: 57.5" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 76.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Lung - Macrophages, Spleen - Macrophages, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041702, HPA041727" Enhanced Supported Nucleoplasm,Vesicles "Intracellular and membrane" Enzyme NA NA 4200000 "Cluster 29: Non-specific - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 38: Sub-cortical - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 8 "Nucleoplasm, Vesicles" "HPA041702: , HPA041727: " "unprognostic (1.89e-1)" "unprognostic (2.57e-2)" "unprognostic (1.60e-1)" "unprognostic (2.37e-2)" "unprognostic (1.31e-1)" "unprognostic (1.46e-2)" "unprognostic (3.34e-2)" "unprognostic (1.13e-1)" "unprognostic (4.00e-3)" "unprognostic (1.37e-2)" "unprognostic (5.31e-2)" "potential prognostic unfavorable (2.15e-4)" "unprognostic (4.40e-3)" "unprognostic (1.45e-3)" "potential prognostic favorable (8.63e-4)" "unprognostic (8.57e-2)" "unprognostic (3.67e-2)" "unprognostic (6.24e-3)" "unprognostic (1.55e-1)" "unprognostic (7.45e-2)" "unprognostic (5.24e-3)" "unprognostic (2.31e-1)" "unprognostic (3.65e-3)" "unprognostic (8.13e-2)" "unprognostic (8.93e-2)" "unprognostic (3.76e-2)" "unprognostic (6.95e-3)" "unprognostic (9.63e-2)" "unprognostic (5.15e-3)" "unprognostic (2.52e-2)" "unprognostic (2.32e-1)" PLA2G1B "PLA2, PLA2A, PPLA2" ENSG00000170890 "Phospholipase A2 group IB" P04054 12 120322115-120327779 "Candidate cardiovascular disease genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Lipid metabolism, Phospholipid metabolism" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 2921 "pancreas: 110913.6" "Cell type enriched" "Detected in some" 129 "Pancreatic acinar cells: 42773.2" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 82 "Pancreatic Adenocarcinoma (TCGA): 1402.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Alveolar cells type 2, Pancreas - Exocrine glandular cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047822, HPA060803" Enhanced "Secreted to digestive system" Enzyme NA NA 1700000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 8: Pancreas - Proteolysis" "Cluster 7: Liver cancer - Metabolism" "Cluster 5: Pancreatic acinar cells - Pancreatic exocrine secretion" 1 "HPA047822: , HPA060803: " "unprognostic (1.47e-2)" "unprognostic (1.75e-2)" "unprognostic (1.72e-1)" "unprognostic (1.47e-1)" "unprognostic (5.57e-3)" "unprognostic (1.23e-3)" "unprognostic (2.66e-2)" "unprognostic (2.87e-3)" "unprognostic (2.25e-1)" "unprognostic (7.91e-2)" "unprognostic (1.27e-1)" "unprognostic (5.36e-2)" "unprognostic (2.11e-1)" PLA2G2A "PLA2B, PLA2L" ENSG00000188257 "Phospholipase A2 group IIA" P14555 1 19975431-19980416 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Inflammatory response, Lipid metabolism, Phospholipid metabolism" "Antimicrobial, Bacteriolytic enzyme, Hydrolase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 1581.2;heart muscle: 2383.2;intestine: 1417.0;liver: 1824.0" "Cell type enriched" "Detected in many" 5 "Paneth cells: 12514.9" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 3345.8" "Region enhanced" "Detected in some" "choroid plexus: 6.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 84.8;Gastric cancer: 164.6" "Lung - Fibroblasts_2, Thyroid gland - Macrophages" "Not detected" "Not detected" "Not detected" "Not detected" HPA015236 Enhanced "Secreted to blood" Enzyme NA NA 1000000 1700000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 12: Non-specific - Vasculature" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 108: Fibroblasts - ECM organization" 1 "HPA015236: " "unprognostic (2.93e-2)" "unprognostic (1.56e-2)" "potential prognostic favorable (2.23e-4)" "unprognostic (1.78e-1)" "unprognostic (1.25e-1)" "unprognostic (4.44e-3)" "unprognostic (9.16e-2)" "potential prognostic unfavorable (3.59e-4)" "unprognostic (4.42e-2)" "unprognostic (3.83e-1)" "potential prognostic unfavorable (7.49e-9)" "potential prognostic unfavorable (1.56e-4)" "unprognostic (1.46e-1)" "unprognostic (8.48e-3)" "unprognostic (6.20e-2)" "unprognostic (1.60e-2)" "unprognostic (2.55e-2)" "unprognostic (2.89e-1)" "unprognostic (8.86e-2)" "unprognostic (2.93e-1)" "unprognostic (1.50e-1)" "unprognostic (3.67e-1)" "unprognostic (5.08e-3)" "unprognostic (5.90e-2)" "potential prognostic unfavorable (6.51e-4)" "unprognostic (3.16e-2)" "unprognostic (3.08e-2)" "unprognostic (1.24e-1)" "unprognostic (1.02e-1)" "unprognostic (1.78e-1)" PLA2G2C UBXN10-AS1 ENSG00000187980 "Phospholipase A2 group IIC" Q5R387 1 20161253-20186518 "Predicted secreted proteins, RAS pathway related proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 5 "intestine: 3.2" "Cell type enhanced" "Detected in many" "Early spermatids: 17.8;Endometrial glandular cells: 10.2;Epididymal principal cells: 70.5;Late primary spermatocytes: 23.2;Late spermatids: 43.1;Mast cells: 17.3;Smooth muscle cells: 30.6" "Cell type enhanced" "Detected in some" "Bergmann glia: 2.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Leukemia: 1.0" "Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Smooth muscle cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted - unknown location" "No annotated function" NA NA "Cluster 77: Intestine - Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" "unprognostic (7.75e-3)" PLA2G2D sPLA2S ENSG00000117215 "Phospholipase A2 group IID" Q9UNK4 1 20111939-20119566 "Enzymes, Metabolic proteins, Predicted secreted proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "lymphoid tissue: 99.6" "Cell type enhanced" "Detected in some" "Kupffer cells: 6.1;Macrophages: 3.1;Plasma cells: 12.6;Retinal horizontal cells: 2.0" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 7 "Testicular Germ Cell Tumor (TCGA): 47.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 3.7;naive B-cell: 3.7;plasmacytoid DC: 2.0" "Group enriched" "Detected in many" 6 "B-cells: 3.7;dendritic cells: 2.0" "Group enriched" "Detected in some" 7 "lymphoma: 2.0;Myeloma: 1.8" "Minor Salivary Gland - Plasma cells" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" Enzyme NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 78: Plasma cells - Antibody production & ER-stress response" 1 "unprognostic (1.01e-1)" "unprognostic (2.29e-3)" "unprognostic (7.98e-2)" "unprognostic (1.75e-2)" "unprognostic (4.42e-2)" "unprognostic (5.11e-2)" "unprognostic (8.62e-2)" "unprognostic (6.89e-3)" "unprognostic (1.58e-2)" "unprognostic (3.41e-3)" "unprognostic (1.11e-1)" "unprognostic (1.77e-1)" "unprognostic (5.44e-2)" "unprognostic (2.10e-2)" "unprognostic (3.95e-1)" "unprognostic (6.35e-2)" "unprognostic (2.72e-1)" "potential prognostic favorable (5.72e-4)" "unprognostic (1.30e-2)" "unprognostic (1.63e-1)" "unprognostic (6.50e-3)" "unprognostic (4.06e-2)" "potential prognostic favorable (1.01e-4)" "unprognostic (8.69e-2)" "unprognostic (1.40e-1)" "unprognostic (7.36e-2)" "unprognostic (5.75e-2)" PLA2G2E ENSG00000188784 "Phospholipase A2 group IIE" Q9NZK7 1 19920009-19923617 "Enzymes, Metabolic proteins, Predicted secreted proteins, RAS pathway related proteins" "Inflammatory response, Lipid metabolism, Phospholipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 5 "lymphoid tissue: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA064085 Uncertain "Secreted - unknown location" Enzyme NA NA "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 32: Non-specific - Cell proliferation" 1 "HPA064085: " PLA2G2F ENSG00000158786 "Phospholipase A2 group IIF" Q9BZM2 1 20139323-20150381 "Enzymes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Immunity, Innate immunity, Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 24 "lymphoid tissue: 7.5;skin 1: 14.3;urinary bladder: 9.8" "Cell type enriched" "Detected in some" 4 "Urothelial cells: 38.7" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 20 "Bladder Urothelial Carcinoma (TCGA): 54.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "Bladder cancer: 6.8" "Stomach - Gastric mucous cells" "Region enriched" "Detected in single" 4 "hippocampal formation: 3.0" "Not detected" "Not detected" "Intracellular and membrane" Immunity NA NA "Cluster 58: Skin - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 69: Urothelial cells - Basic cellular functions" "potential prognostic favorable (5.72e-4)" "unprognostic (8.71e-2)" "unprognostic (2.76e-2)" "unprognostic (3.33e-1)" "unprognostic (6.75e-2)" PLA2G3 GIII-SPLA2 ENSG00000100078 "Phospholipase A2 group III" Q9NZ20 22 31134807-31140508 "Enzymes, Metabolic proteins, Predicted secreted proteins, RAS pathway related proteins" "Cilium biogenesis/degradation, Lipid metabolism, Mast cell degranulation, Phospholipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "cervix: 5.0;esophagus: 14.0;skin 1: 15.1;vagina: 7.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 15.8;Breast lactating cells: 106.5;Esophageal apical cells: 17.3;Esophageal suprabasal cells: 26.9;Suprabasal keratinocytes: 20.9;Tuft cells: 11.5" "Group enriched" "Detected in some" 5 "hippocampal CA4: 1.6;lower rhombic lip: 6.0" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 5.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 11.5" "Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary gland basal cells, Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA021016 Uncertain Approved "Endoplasmic reticulum,Golgi apparatus" "Secreted to blood" Enzyme NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 49: Hindbrain - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 4: Breast lactating luminal cells - Lactation" "Endoplasmic reticulum, Golgi apparatus" "HPA021016: " "unprognostic (2.02e-1)" "potential prognostic favorable (6.78e-5)" "unprognostic (2.07e-2)" "unprognostic (1.61e-1)" "potential prognostic favorable (2.61e-4)" "unprognostic (1.08e-2)" "unprognostic (4.11e-3)" "unprognostic (2.13e-1)" "unprognostic (1.01e-1)" "unprognostic (2.10e-2)" "unprognostic (1.38e-1)" "unprognostic (2.77e-2)" PLA2G4A "cPLA2-alpha, PLA2G4" ENSG00000116711 "Phospholipase A2 group IVA" P47712 1 186828949-186988981 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Glycerol metabolism, Leukotriene biosynthesis, Lipid biosynthesis, Lipid degradation, Lipid metabolism, Phospholipid degradation, Phospholipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 82.0;seminal vesicle: 45.5" "Cell type enhanced" "Detected in many" "Fallopian tube ciliated cells: 135.3;Microglia: 306.8;Neutrophil progenitors: 270.1;Urothelial cells: 228.8" "Group enriched" "Detected in many" 4 "central nervous system macrophage: 388.1;endothelial cell: 394.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 6.8;eosinophil: 7.9;intermediate monocyte: 8.4;myeloid DC: 7.7;non-classical monocyte: 4.0;plasmacytoid DC: 3.1" "Group enriched" "Detected in many" 7 "dendritic cells: 7.7;granulocytes: 7.9;monocytes: 8.4" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Pituitary gland - Fibroblasts, Prostate - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010050, HPA050062, HPA054206" Approved Supported Vesicles,Cytosol NA NA 29000 "Cluster 29: Non-specific - Unknown function" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 20 Cytosol Vesicles "CAB010050: , HPA050062: , HPA054206: " "unprognostic (2.55e-1)" "unprognostic (2.10e-3)" "unprognostic (4.15e-1)" "unprognostic (2.07e-1)" "unprognostic (9.48e-2)" "unprognostic (1.89e-2)" "unprognostic (1.54e-1)" "unprognostic (1.68e-1)" "unprognostic (2.23e-3)" "unprognostic (7.24e-2)" "potential prognostic favorable (8.47e-4)" "unprognostic (1.38e-1)" "unprognostic (1.42e-1)" "unprognostic (4.72e-2)" "unprognostic (4.73e-2)" "unprognostic (7.33e-2)" "unprognostic (2.14e-1)" "unprognostic (7.06e-2)" "unprognostic (1.31e-2)" "unprognostic (7.00e-2)" "unprognostic (2.77e-1)" "unprognostic (4.34e-3)" "unprognostic (2.29e-1)" "unprognostic (5.80e-2)" "unprognostic (8.62e-2)" "unprognostic (1.85e-1)" "unprognostic (7.62e-2)" "unprognostic (3.45e-2)" "unprognostic (7.07e-2)" "potential prognostic favorable (8.08e-4)" PLA2G4B "cPLA2-beta, HsT16992" ENSG00000243708 "Phospholipase A2 group IVB" P0C869 15 41837775-41848147 "Enzymes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 27 "Astrocytes: 22.5;Bergmann glia: 13.3;Brain excitatory neurons: 18.4;Brain inhibitory neurons: 14.9;Choroid plexus epithelial cells: 9.2;Ependymal cells: 10.0;Microglia: 9.0;Oligodendrocyte progenitor cells: 16.3;Oligodendrocytes: 11.9;Other brain neurons: 14.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "naive B-cell: 1.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 2: Non-specific - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 2: Cerebellar granular cells - Neuronal signaling" "unprognostic (3.94e-1)" "unprognostic (3.80e-2)" "unprognostic (1.32e-2)" "unprognostic (4.34e-2)" "unprognostic (1.53e-1)" "unprognostic (1.04e-1)" "unprognostic (2.26e-2)" "potential prognostic unfavorable (2.78e-6)" "unprognostic (9.46e-2)" "unprognostic (2.34e-1)" "unprognostic (1.56e-1)" "unprognostic (9.54e-2)" "unprognostic (3.43e-2)" "unprognostic (1.73e-2)" "unprognostic (1.46e-1)" "unprognostic (3.44e-2)" "unprognostic (2.53e-2)" "unprognostic (1.10e-3)" "unprognostic (1.35e-3)" "unprognostic (2.21e-1)" "unprognostic (7.00e-2)" "unprognostic (3.73e-2)" "unprognostic (2.96e-1)" "unprognostic (9.03e-2)" "unprognostic (1.54e-1)" "unprognostic (2.16e-1)" PLA2G4C cPLA2-gamma ENSG00000105499 "Phospholipase A2 group IVC" Q9UP65 19 48047843-48110817 "Enzymes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Host-virus interaction, Lipid metabolism, Phospholipid metabolism" "Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 73.1;skeletal muscle: 62.5" "Cell type enhanced" "Detected in many" "Bergmann glia: 176.4;Müller glia: 121.5;Myonuclei: 462.1;Oligodendrocytes: 152.6;Pancreatic duct cells: 121.9;Retinal bipolar cells: 178.0;Rod photoreceptor cells: 288.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 5.8" "Group enriched" "Detected in many" 4 "B-cells: 4.1;monocytes: 5.8" "Low cancer specificity" "Detected in many" "Breast - T-cells, Heart muscle - Cardiomyocytes, Stomach - Fibroblasts" "Not detected" "Not detected" HPA043083 Approved Approved Cytosol NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 1 Cytosol "HPA043083: " "unprognostic (6.06e-2)" "unprognostic (2.84e-1)" "unprognostic (9.34e-2)" "unprognostic (6.07e-3)" "unprognostic (6.39e-2)" "unprognostic (4.40e-2)" "unprognostic (2.00e-1)" "unprognostic (1.93e-1)" "unprognostic (1.41e-2)" "unprognostic (1.71e-1)" "potential prognostic favorable (1.46e-6)" "unprognostic (1.05e-1)" "unprognostic (1.66e-2)" "unprognostic (8.06e-2)" "unprognostic (2.23e-3)" "unprognostic (1.09e-1)" "unprognostic (3.26e-1)" "unprognostic (1.77e-1)" "unprognostic (9.69e-2)" "unprognostic (7.14e-2)" "unprognostic (1.31e-1)" "unprognostic (4.27e-3)" "unprognostic (1.01e-1)" "unprognostic (1.31e-1)" "unprognostic (2.00e-1)" "unprognostic (4.62e-2)" "unprognostic (2.13e-1)" "unprognostic (8.37e-2)" "unprognostic (2.07e-3)" "unprognostic (2.60e-1)" "unprognostic (3.42e-2)" PLA2G4D cPLA2delta ENSG00000159337 "Phospholipase A2 group IVD" Q86XP0 15 42067009-42094562 "Enzymes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "cervix: 14.6;prostate: 17.9;skin 1: 13.6;vagina: 18.2" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 2.1;Epicardial cells: 4.5;Epididymal basal cells: 2.5;Esophageal apical cells: 11.0;Foveolar cells: 2.3;Prostatic glandular cells: 7.0;Retinal horizontal cells: 2.0;Somatotrophs: 4.4;Suprabasal keratinocytes: 11.0;Thyrotrophs: 3.6" "Cell type enhanced" "Detected in some" "hippocampal CA1-3: 2.7" "Group enriched" "Detected in some" 4 "Bladder Urothelial Carcinoma (TCGA): 1.7;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 1.8;Head and Neck Squamous Cell Carcinoma (TCGA): 2.8;Prostate Adenocarcinoma (TCGA): 2.2;Skin Cutaneous Melanoma (TCGA): 3.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA074206 Approved "Plasma membrane,Cytosol" NA NA "Cluster 58: Skin - Keratinization" "Cluster 29: Forebrain - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" Cytosol "Plasma membrane" "HPA074206: " "unprognostic (2.20e-1)" "unprognostic (1.28e-1)" "unprognostic (2.56e-3)" "unprognostic (9.02e-2)" "unprognostic (2.14e-1)" "unprognostic (1.75e-1)" "unprognostic (2.00e-1)" PLA2G4E FLJ45651 ENSG00000188089 "Phospholipase A2 group IVE" Q3MJ16 15 41981394-42051190 "Enzymes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "skin 1: 14.5" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 42.4;Cone photoreceptor cells: 20.7;Corticotrophs: 16.6;Early spermatids: 17.9;Esophageal apical cells: 56.4;Esophageal basal cells: 19.7;Esophageal suprabasal cells: 64.0;Late spermatids: 26.7;Suprabasal keratinocytes: 175.5" "Cell type enhanced" "Detected in some" "hippocampal CA1-3: 5.2;hippocampal CA4: 3.7;midbrain-derived inhibitory: 4.4" "Cancer enriched" "Detected in some" 4 "Head and Neck Squamous Cell Carcinoma (TCGA): 8.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pituitary gland - Corticotropes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041105, HPA072562" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 58: Skin - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" "Vesicles, Cytosol" "HPA041105: , HPA072562: " "unprognostic (1.74e-1)" "unprognostic (1.44e-1)" "unprognostic (3.56e-1)" "unprognostic (1.89e-1)" "unprognostic (1.91e-1)" PLA2G4F PLA2G4F/Z ENSG00000168907 "Phospholipase A2 group IVF" Q68DD2 15 42139034-42156636 "Enzymes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism, Phospholipid degradation, Phospholipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "skin 1: 73.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 75.7;Colonocytes: 17.4;Distal convoluted tubule cells: 23.1;Endometrial luminal cells: 25.3;Epididymal clear cells: 20.4;Esophageal suprabasal cells: 21.6;Foveolar cells: 17.3;Prostatic glandular cells: 20.5;Renal collecting duct intercalated cells: 21.7;Renal connecting tubule cells: 26.8;Suprabasal keratinocytes: 25.8" "Cell type enriched" "Detected in single" 5 "medium spiny neuron: 1.3" "Cancer enriched" "Detected in many" 6 "Kidney Chromophobe (TCGA): 39.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 3.4;prostate cancer: 3.4" "Breast - Breast glandular cells, Colon - Colon enterocytes, Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2, Pituitary gland - Corticotropes, Prostate - Prostate glandular cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA042713, HPA056752" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 37: Skin - Keratinization" "Cluster 34: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 81: Alveolar cells - Lung function" Vesicles Nucleoplasm "HPA042713: , HPA056752: " "unprognostic (3.22e-1)" "unprognostic (1.38e-1)" "unprognostic (3.13e-3)" "unprognostic (1.98e-1)" "unprognostic (3.64e-2)" "unprognostic (7.73e-2)" "unprognostic (1.53e-1)" "unprognostic (2.58e-2)" "unprognostic (4.69e-3)" "unprognostic (1.41e-3)" "unprognostic (2.56e-1)" "unprognostic (6.69e-2)" "unprognostic (1.25e-1)" "unprognostic (1.73e-1)" "unprognostic (2.41e-1)" "unprognostic (1.07e-3)" "unprognostic (6.41e-2)" "unprognostic (4.93e-2)" "unprognostic (2.10e-1)" PLA2G5 ENSG00000127472 "Phospholipase A2 group V" P39877 1 20028179-20091911 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted secreted proteins, RAS pathway related proteins" "Fatty acid metabolism, Lipid degradation, Lipid metabolism, Phagocytosis, Phospholipid degradation, Phospholipid metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 55.7;heart muscle: 46.4" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 76.6;Cone photoreceptor cells: 296.0;Hepatic stellate cells: 258.2;Leydig cells: 321.4;Ovarian stromal cells: 210.1;Pericytes: 235.1;Peritubular myoid cells: 243.6;Retinal pigment epithelial cells: 370.9;Vascular smooth muscle cells: 80.8" "Cell type enhanced" "Detected in some" "astrocyte: 35.1;Bergmann glia: 68.1;choroid plexus epithelial cell: 61.1" "Cancer enriched" "Detected in some" 8 "Glioblastoma Multiforme (TCGA): 21.8" "Region enhanced" "Detected in all" "choroid plexus: 32.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Prostate - Smooth muscle cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA053361 Approved "Secreted in other tissues" Enzyme NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 72: Neuronal - Signal transduction" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "HPA053361: " "unprognostic (1.08e-1)" "unprognostic (9.34e-3)" "potential prognostic unfavorable (2.17e-6)" "unprognostic (1.08e-2)" "unprognostic (1.68e-2)" "unprognostic (2.38e-1)" "unprognostic (4.01e-2)" "unprognostic (1.38e-1)" "unprognostic (2.79e-1)" "unprognostic (2.03e-2)" PLA2G6 "iPLA2, iPLA2beta, NBIA2, PARK14, PNPLA9" ENSG00000184381 "Phospholipase A2 group VI" O60733 22 38111495-38214778 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Chemotaxis, Lipid metabolism, Phospholipid metabolism" "Calmodulin-binding, Hydrolase" "Disease variant, Dystonia, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 162.1;Enterocytes: 176.3;Epicardial cells: 627.7;Megakaryocyte-Erythroid progenitors: 250.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 3.8" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Leukemia: 27.8" "Adipose subcutaneous - Adipocytes (Subcutaneous), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000825, HPA001171" Approved Supported "Nuclear speckles,Plasma membrane,Microtubules" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 21: Testis - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 9 "Plasma membrane" "Nuclear speckles, Microtubules" "HPA000825: , HPA001171: " "unprognostic (5.65e-2)" "unprognostic (5.72e-2)" "unprognostic (4.84e-2)" "unprognostic (1.64e-3)" "unprognostic (1.84e-1)" "unprognostic (7.26e-2)" "unprognostic (1.39e-1)" "unprognostic (5.23e-2)" "unprognostic (3.27e-3)" "unprognostic (3.51e-2)" "potential prognostic unfavorable (2.40e-4)" "unprognostic (5.50e-2)" "unprognostic (7.05e-2)" "unprognostic (1.61e-2)" "unprognostic (6.32e-2)" "unprognostic (1.58e-1)" "unprognostic (3.68e-1)" "unprognostic (2.31e-1)" "unprognostic (4.41e-3)" "unprognostic (1.62e-1)" "unprognostic (9.42e-3)" "unprognostic (1.53e-3)" "unprognostic (1.14e-2)" "unprognostic (2.72e-1)" "unprognostic (5.02e-3)" "potential prognostic favorable (2.31e-7)" "unprognostic (1.27e-1)" "unprognostic (1.20e-1)" "unprognostic (9.83e-2)" "unprognostic (1.54e-1)" "unprognostic (8.21e-2)" PLA2G7 "LDL-PLA2, PAFAH" ENSG00000146070 "Phospholipase A2 group VII" Q13093 6 46704201-46735693 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Lipid degradation, Lipid metabolism, Phospholipid degradation, Phospholipid metabolism" Hydrolase "Asthma, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 25.6;placenta: 21.8" "Cell type enriched" "Detected in some" 4 "Hofbauer cells: 504.3" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 43.1" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 63.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 43.4" "Group enriched" "Detected in many" 53 "dendritic cells: 14.1;monocytes: 43.4" "Cancer enriched" "Detected in some" 8 "prostate cancer: 15.1" "Adipose subcutaneous - Macrophages, Minor Salivary Gland - Macrophages, Pituitary gland - Thyrotropes, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells, Spleen - Macrophages, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" Enzyme NA NA 7380000 55000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 30: White matter - Myelination" "Cluster 60: Prostate cancer - Unknown function" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 1 "unprognostic (2.09e-2)" "unprognostic (1.91e-2)" "unprognostic (2.39e-1)" "unprognostic (2.83e-1)" "unprognostic (2.47e-1)" "unprognostic (1.17e-1)" "unprognostic (8.56e-2)" "unprognostic (1.26e-1)" "unprognostic (1.30e-1)" "unprognostic (4.39e-2)" "potential prognostic favorable (6.02e-4)" "unprognostic (1.27e-1)" "unprognostic (2.17e-2)" "unprognostic (2.73e-2)" "unprognostic (2.35e-1)" "unprognostic (2.34e-1)" "unprognostic (2.02e-1)" "unprognostic (2.97e-1)" "unprognostic (1.28e-1)" "unprognostic (1.51e-1)" "unprognostic (3.98e-2)" "unprognostic (1.08e-2)" "unprognostic (4.92e-2)" "unprognostic (1.16e-1)" "unprognostic (4.99e-2)" "unprognostic (3.49e-2)" "unprognostic (4.11e-1)" "unprognostic (6.09e-2)" "unprognostic (1.56e-1)" "unprognostic (6.39e-2)" "unprognostic (3.58e-1)" PLA2R1 "CLEC13C, PLA2-R, PLA2G1R, PLA2IR" ENSG00000153246 "Phospholipase A2 receptor 1" Q13018 2 159932006-160062615 "Predicted membrane proteins, Predicted secreted proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 36.8;thyroid gland: 39.3" "Cell type enriched" "Detected in many" 8 "Podocytes: 6773.3" "Cell type enhanced" "Detected in many" "fibroblast: 249.4;pericyte: 230.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Kidney - Podocytes, Liver - Hepatic stellate cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB068217, CAB068218" Approved Approved Cytosol "Secreted to blood" Receptor NA NA 2600000 "Cluster 33: Thyroid gland - Tissue development" "Cluster 2: Neurons - Nucleosome" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 57: Podocytes - Glomerular filtration" Cytosol "CAB068217: , CAB068218: " "unprognostic (1.60e-2)" "unprognostic (3.34e-1)" "unprognostic (1.38e-1)" "unprognostic (3.98e-2)" "unprognostic (3.03e-1)" "unprognostic (1.20e-1)" "unprognostic (3.86e-2)" "unprognostic (5.26e-2)" "unprognostic (1.78e-3)" "unprognostic (2.83e-1)" "unprognostic (1.67e-1)" "unprognostic (1.41e-1)" "unprognostic (3.18e-2)" "unprognostic (9.23e-2)" "unprognostic (4.88e-2)" "unprognostic (4.20e-3)" "unprognostic (1.76e-3)" "unprognostic (1.54e-2)" "unprognostic (1.10e-3)" "unprognostic (4.22e-1)" "unprognostic (1.35e-1)" "unprognostic (2.57e-1)" "potential prognostic unfavorable (1.50e-4)" "unprognostic (1.70e-1)" "unprognostic (3.87e-2)" "unprognostic (3.08e-1)" PLAA "DOA1, FLJ11281, FLJ12699, PLA2P, PLAP" ENSG00000137055 "Phospholipase A2 activating protein" Q9Y263 9 26903372-26947242 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Neurogenesis "Developmental protein" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005035, HPA020994, HPA020996" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 20000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 23 "Plasma membrane, Cytosol" Nucleoplasm "CAB005035: , HPA020994: , HPA020996: " "unprognostic (9.06e-2)" "unprognostic (7.44e-2)" "unprognostic (2.36e-1)" "potential prognostic unfavorable (4.18e-4)" "unprognostic (1.03e-1)" "unprognostic (5.88e-3)" "unprognostic (7.11e-2)" "unprognostic (1.44e-1)" "unprognostic (1.79e-1)" "unprognostic (1.88e-1)" "potential prognostic favorable (1.11e-5)" "unprognostic (6.63e-2)" "unprognostic (9.93e-2)" "unprognostic (4.10e-2)" "unprognostic (5.74e-2)" "unprognostic (4.00e-2)" "unprognostic (2.59e-2)" "unprognostic (4.40e-1)" "unprognostic (1.02e-1)" "unprognostic (1.27e-2)" "unprognostic (2.92e-2)" "unprognostic (2.60e-2)" "unprognostic (8.01e-2)" "unprognostic (3.17e-2)" "unprognostic (3.56e-2)" "unprognostic (2.80e-1)" "unprognostic (2.64e-2)" "unprognostic (2.05e-1)" "unprognostic (4.12e-1)" "potential prognostic unfavorable (1.85e-4)" "unprognostic (8.75e-2)" PLAAT1 "A-C1, H-REV107, HRASLS, HRASLS1, PLA/AT1, PLAAT-1" ENSG00000127252 "Phospholipase A and acyltransferase 1" Q9HDD0 3 193241128-193277738 "Enzymes, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "skeletal muscle: 84.4;testis: 77.8;tongue: 41.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 140.8;Early spermatids: 534.6;Late primary spermatocytes: 688.7;Late spermatids: 174.4;Myonuclei: 78.9;Oligodendrocyte progenitor cells: 177.0;Platelets: 147.6" "Group enriched" "Detected in many" 5 "committed oligodendrocyte precursor: 229.6;oligodendrocyte precursor cell: 195.6" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 19.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Pituitary gland - Undifferentiated cells (Pituitary gland), Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051179 Uncertain Approved "Focal adhesion sites,Cytosol" No No "Cluster 4: Neutrophils - Degranulation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 11: Neuronal - Sensory perception" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 7 "Focal adhesion sites" Cytosol "HPA051179: " "unprognostic (6.54e-3)" "unprognostic (9.41e-3)" "unprognostic (1.18e-2)" "unprognostic (1.93e-1)" "unprognostic (4.93e-3)" "unprognostic (1.21e-1)" "unprognostic (3.85e-1)" "unprognostic (1.42e-2)" "unprognostic (2.87e-2)" "unprognostic (3.02e-1)" "unprognostic (4.86e-2)" "potential prognostic favorable (3.81e-4)" "unprognostic (4.30e-2)" "unprognostic (2.86e-1)" "unprognostic (1.62e-1)" "potential prognostic favorable (4.73e-4)" "unprognostic (5.16e-2)" "unprognostic (7.00e-3)" "unprognostic (2.01e-3)" "unprognostic (6.60e-3)" PLAAT2 "FLJ20556, HRASLS2, PLAAT-2" ENSG00000133328 "Phospholipase A and acyltransferase 2" Q9NWW9 11 63552770-63563379 "Enzymes, Metabolic proteins, Predicted membrane proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 63.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 33.1;Colonocytes: 75.2;Endometrial ciliated cells: 54.0;Enterocytes: 79.1;Epididymal efferent duct ciliated cells: 90.7;Fallopian tube ciliated cells: 26.4;Foveolar cells: 124.2;Ocular epithelial cells: 49.4;Respiratory basal cells: 25.8;Respiratory ciliated cells: 63.7" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 8 "memory B-cell: 17.4;naive B-cell: 8.3" "Lineage enriched" "Detected in many" 10 "B-cells: 17.4" "Cancer enhanced" "Detected in many" "Myeloma: 30.0" "Breast - Breast glandular cells, Breast - Breast glandular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Stomach - Gastric mucous cells" HPA058997 Approved Approved Mitochondria NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 77: Intestine - Digestion" "Cluster 11: White matter - Signal transduction" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 5 Mitochondria "HPA058997: " "unprognostic (2.09e-1)" "unprognostic (9.61e-2)" "potential prognostic favorable (4.31e-4)" "unprognostic (3.62e-1)" "unprognostic (1.82e-2)" "unprognostic (2.16e-1)" "unprognostic (6.29e-3)" "unprognostic (1.77e-2)" "unprognostic (1.35e-2)" "unprognostic (1.23e-1)" "unprognostic (2.93e-2)" "unprognostic (4.40e-1)" "unprognostic (7.38e-2)" "unprognostic (1.57e-1)" "unprognostic (9.99e-3)" "unprognostic (2.15e-3)" "potential prognostic unfavorable (5.09e-5)" "unprognostic (3.98e-3)" "unprognostic (3.02e-1)" "unprognostic (3.79e-1)" "unprognostic (2.61e-2)" "unprognostic (1.15e-2)" PLAAT3 "AdPLA, H-REV107-1, HRASLS3, HREV107, HREV107-3, MGC118754., PLA2G16, PLAAT-3" ENSG00000176485 "Phospholipase A and acyltransferase 3" P53816 11 63573195-63616883 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Host-virus interaction, Lipid degradation, Lipid metabolism" "Hydrolase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 299.2;brain: 318.6" "Cell type enhanced" "Detected in many" "Adipocytes: 395.5;Endometrial glandular cells: 360.4;Extravillous trophoblasts: 466.1;Granulosa cells: 489.0;Migrating cytotrophoblasts: 519.2;Oligodendrocytes: 348.4;Syncytiotrophoblasts: 336.9" "Cell type enhanced" "Detected in all" "oligodendrocyte: 474.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 188.1" "Group enriched" "Detected in all" 6 "dendritic cells: 188.1;T-cells: 55.1" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011749, HPA058997" Approved Approved Mitochondria,Cytosol NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 51: Secretory epithelial cells - Mixed function" 6 Mitochondria Cytosol "HPA011749: , HPA058997: " "unprognostic (2.50e-1)" "unprognostic (4.61e-2)" "unprognostic (3.57e-2)" "unprognostic (6.83e-2)" "unprognostic (2.84e-3)" "unprognostic (2.27e-2)" "potential prognostic unfavorable (4.78e-6)" "unprognostic (1.78e-2)" "unprognostic (1.29e-1)" "potential prognostic favorable (5.58e-5)" "unprognostic (2.56e-2)" "potential prognostic favorable (1.53e-6)" "unprognostic (5.92e-2)" "unprognostic (3.28e-2)" "unprognostic (1.32e-1)" "unprognostic (1.65e-1)" "unprognostic (1.37e-1)" "unprognostic (1.13e-1)" "unprognostic (1.35e-1)" "potential prognostic unfavorable (9.05e-7)" "unprognostic (1.27e-2)" "unprognostic (2.86e-2)" "unprognostic (1.46e-1)" "unprognostic (1.92e-1)" "unprognostic (1.75e-2)" "unprognostic (7.07e-2)" "unprognostic (3.84e-1)" "unprognostic (4.13e-3)" "unprognostic (1.59e-2)" PLAAT4 "HRASLS4, PLAAT-4, RARRES3, RIG1, TIG3" ENSG00000133321 "Phospholipase A and acyltransferase 4" Q9UL19 11 63536808-63546462 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 345.3;Enterocytes: 531.5;Epididymal clear cells: 414.4;Epididymal efferent duct ciliated cells: 297.6;Respiratory ciliated cells: 255.1;Respiratory secretory cells: 271.9;Salivary duct cells: 266.5;Salivary ionocytes: 357.9" "Cell type enriched" "Detected in many" 4 "leukocyte: 56.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "pancreatic cancer: 137.3" "Breast - Breast glandular cells, Spleen - T-cells" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 6 "unprognostic (3.36e-1)" "unprognostic (3.19e-3)" "potential prognostic favorable (6.83e-4)" "unprognostic (2.53e-1)" "unprognostic (1.52e-1)" "unprognostic (6.89e-2)" "unprognostic (8.49e-2)" "unprognostic (1.38e-2)" "unprognostic (2.38e-2)" "unprognostic (3.12e-1)" "unprognostic (3.13e-1)" "unprognostic (1.52e-1)" "unprognostic (3.06e-1)" "unprognostic (9.37e-2)" "unprognostic (2.14e-1)" "unprognostic (2.75e-1)" "unprognostic (1.41e-1)" "unprognostic (1.29e-1)" "unprognostic (1.04e-3)" "potential prognostic unfavorable (3.31e-5)" "unprognostic (1.44e-2)" "unprognostic (2.74e-1)" "unprognostic (4.16e-2)" "unprognostic (1.29e-1)" "unprognostic (4.47e-1)" "unprognostic (3.73e-1)" "unprognostic (1.55e-1)" "unprognostic (7.38e-3)" "unprognostic (1.41e-1)" PLAAT5 "HRASLS5, HRLP5, iNAT, PLAAT-5" ENSG00000168004 "Phospholipase A and acyltransferase 5" Q96KN8 11 63461404-63491194 "Enzymes, Predicted intracellular proteins" "Lipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 15.5;pancreas: 12.8;testis: 51.6" "Cell type enhanced" "Detected in many" "Early spermatids: 417.6;Late primary spermatocytes: 361.1;Late spermatids: 1549.0" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Breast Invasive Carcinoma (TCGA): 3.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 65 "basophil: 5.4;eosinophil: 16.4" "Lineage enriched" "Detected in single" 97 "granulocytes: 16.4" "Cancer enhanced" "Detected in some" "ovarian cancer: 1.5" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Minor Salivary Gland - Adipocytes (Minor salivary gland), Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA079686 Approved Nucleoplasm,Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 57: Testis - Spermatogenesis" "Cluster 22: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 1 Cytosol Nucleoplasm "HPA079686: " "unprognostic (1.87e-1)" "validated prognostic unfavorable (8.29e-4)" "validated prognostic unfavorable (8.06e-4)" "unprognostic (3.55e-1)" "unprognostic (1.50e-1)" "unprognostic (7.17e-2)" "unprognostic (1.07e-1)" "unprognostic (1.96e-1)" PLAC1 "CT92, OOSP2B, OOSP2L" ENSG00000170965 "Placenta enriched 1" Q9HBJ0 X 134565838-134764322 "Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 29 "placenta: 26.2" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 10.6;Differentiating spermatogonia: 13.4;Early primary spermatocytes: 22.9;Fibroblasts: 25.3;Leydig cells: 9.4;Peritubular myoid cells: 12.6;Syncytiotrophoblasts: 17.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 6.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA000163, HPA063425" Enhanced Approved Vesicles,Cytosol "Secreted in female reproductive system" "Developmental protein" NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 108: Fibroblasts - ECM organization" Vesicles Cytosol "HPA000163: , HPA063425: " "unprognostic (7.90e-2)" "unprognostic (1.83e-1)" "unprognostic (2.92e-1)" "unprognostic (4.96e-3)" "unprognostic (8.33e-3)" "unprognostic (5.49e-3)" "unprognostic (3.52e-3)" "unprognostic (2.35e-1)" "unprognostic (1.43e-2)" "unprognostic (1.86e-1)" "unprognostic (1.62e-1)" PLAC8 "C15, onzin" ENSG00000145287 "Placenta associated 8" Q9NZF1 4 83090048-83137075 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 345.6;intestine: 221.2;lymphoid tissue: 149.0" "Cell type enhanced" "Detected in many" "Colonocytes: 1933.5;Enterocytes: 527.7;Esophageal apical cells: 2723.8;Extravillous trophoblasts: 968.2;Foveolar cells: 726.0;Kupffer cells: 694.9;Monocyte progenitors: 404.8;Neutrophil progenitors: 486.0;pDCs: 850.8;Respiratory ciliated cells: 591.7;Respiratory deuterosomal cells: 524.5;Respiratory secretory cells: 735.6" "Cell type enriched" "Detected in many" 12 "leukocyte: 141.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 2328.2" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 300.0" "Adipose subcutaneous - T-cells, Colon - Colon enterocytes, Prostate - T-cells, Stomach - Gastric mucous cells, Thyroid gland - T-cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA040465, HPA077912" Enhanced Approved Cytosol NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" Cytosol "HPA040465: , HPA077912: " "unprognostic (1.83e-2)" "potential prognostic favorable (4.48e-5)" "unprognostic (1.52e-2)" "unprognostic (1.25e-2)" "unprognostic (1.62e-2)" "unprognostic (3.96e-2)" "unprognostic (2.03e-1)" "unprognostic (1.50e-2)" "unprognostic (2.73e-2)" "unprognostic (6.18e-2)" "unprognostic (2.56e-2)" "unprognostic (1.09e-2)" "unprognostic (1.10e-2)" "unprognostic (1.70e-1)" "unprognostic (5.67e-2)" "unprognostic (4.28e-2)" "unprognostic (5.71e-2)" "unprognostic (1.09e-2)" "unprognostic (1.33e-2)" "unprognostic (1.30e-1)" "unprognostic (2.38e-3)" "unprognostic (4.09e-3)" "unprognostic (1.41e-1)" "unprognostic (2.12e-1)" "unprognostic (9.46e-2)" "unprognostic (9.63e-2)" "unprognostic (2.46e-1)" "unprognostic (6.88e-2)" "unprognostic (6.55e-3)" "unprognostic (5.74e-2)" "unprognostic (5.85e-2)" PLAC8L1 ENSG00000173261 "PLAC8 like 1" A1L4L8 5 146084313-146105577 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "testis: 5.7" "Group enriched" "Detected in many" 8 "Early spermatids: 563.4;Late primary spermatocytes: 180.0;Late spermatids: 388.8" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA074266 Approved Nucleoplasm NA NA "Cluster 67: Testis - Mixed function" "Cluster 34: Non-specific - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 9 Nucleoplasm "HPA074266: " "unprognostic (6.49e-3)" "unprognostic (2.51e-3)" "unprognostic (1.08e-1)" PLAC9 ENSG00000189129 "Placenta associated 9" Q5JTB6 10 80131682-80145359 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 215.8" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 291.6;Fibroblasts: 634.7;Hepatic stellate cells: 290.5;Leydig cells: 781.6;Lymphatic endothelial cells: 186.8;Pericytes: 298.9;Peritubular myoid cells: 616.8;Retinal pigment epithelial cells: 541.4;Vascular smooth muscle cells: 424.2" "Group enriched" "Detected in many" 11 "choroid plexus epithelial cell: 57.4;fibroblast: 94.7;pericyte: 205.0;vascular associated smooth muscle cell: 124.1" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "choroid plexus: 104.4" "Immune cell enhanced" "Detected in single" "eosinophil: 1.0" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.0" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Colon - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "spinal cord: 50.7" HPA043469 Uncertain "Secreted - unknown location" "No annotated function" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 6 "HPA043469: " "unprognostic (3.90e-2)" "unprognostic (2.93e-1)" "unprognostic (1.03e-1)" "potential prognostic favorable (5.59e-4)" "unprognostic (6.24e-2)" "unprognostic (1.95e-1)" "unprognostic (3.27e-1)" "unprognostic (1.61e-1)" "unprognostic (2.06e-1)" "unprognostic (6.12e-2)" "unprognostic (1.06e-2)" "potential prognostic favorable (1.97e-4)" "unprognostic (7.05e-2)" "unprognostic (8.75e-3)" "unprognostic (4.10e-2)" "unprognostic (6.04e-3)" "unprognostic (1.38e-2)" "unprognostic (2.57e-2)" "unprognostic (4.09e-1)" "unprognostic (2.42e-3)" "unprognostic (9.37e-2)" "unprognostic (1.24e-2)" "potential prognostic favorable (9.36e-4)" "unprognostic (1.50e-2)" "unprognostic (1.93e-1)" "unprognostic (9.79e-2)" "unprognostic (7.65e-2)" "unprognostic (2.51e-2)" "unprognostic (4.81e-2)" "unprognostic (2.07e-1)" "unprognostic (6.52e-2)" PLAG1 ZNF912 ENSG00000181690 "PLAG1 zinc finger" Q6DJT9 8 56160909-56211324 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Dwarfism, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 7.2" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 127.6;Corticotrophs: 129.4;Lactotrophs: 105.7;Microglia: 124.5;Pituitary stem cells: 117.2;Thyrotrophs: 87.9" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 142.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA072290 Supported "Nucleoplasm,Nuclear speckles,Centrosome,Cytosol" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 42: Retina - Visual perception" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 1 "Nucleoplasm, Nuclear speckles" "Centrosome, Cytosol" "HPA072290: " "unprognostic (1.38e-1)" "unprognostic (8.65e-2)" "unprognostic (4.64e-2)" "unprognostic (1.09e-2)" "unprognostic (3.47e-2)" "unprognostic (1.07e-1)" "unprognostic (1.51e-2)" "unprognostic (2.22e-1)" "unprognostic (2.50e-1)" "unprognostic (1.04e-1)" "unprognostic (2.68e-1)" "unprognostic (1.46e-1)" "unprognostic (1.30e-1)" "unprognostic (1.81e-2)" "unprognostic (8.76e-2)" "unprognostic (2.71e-2)" "potential prognostic unfavorable (6.79e-5)" "unprognostic (2.74e-1)" "unprognostic (4.02e-3)" "unprognostic (3.26e-2)" "unprognostic (3.18e-1)" "unprognostic (1.35e-2)" "unprognostic (3.70e-2)" PLAGL1 "LOT1, ZAC" ENSG00000118495 "PLAG1 like zinc finger 1" Q9UM63 6 143940300-144064599 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 232.2" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 548.6;Corticotrophs: 480.4;Fibro-adipogenic progenitors: 464.3;Leydig cells: 378.5;Somatotrophs: 1408.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Rhabdoid: 70.2" "Adipose subcutaneous - Adipose progenitor cells, Pituitary gland - Somatotropes, Skeletal muscle - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055706 Supported "Nuclear bodies,Golgi apparatus,Vesicles" No No "Cluster 7: Non-specific - Innate immune response" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 5: Rhabdoid - Unknown function" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 10 "Nuclear bodies" "Golgi apparatus, Vesicles" "HPA055706: " "unprognostic (2.94e-1)" "unprognostic (4.93e-3)" "unprognostic (7.52e-3)" "unprognostic (5.20e-3)" "unprognostic (2.45e-1)" "unprognostic (9.23e-3)" "unprognostic (5.43e-2)" "unprognostic (2.06e-1)" "unprognostic (2.96e-1)" "unprognostic (2.88e-2)" "unprognostic (1.43e-1)" "unprognostic (7.77e-2)" "unprognostic (2.32e-2)" "unprognostic (3.67e-2)" "unprognostic (2.99e-2)" "unprognostic (2.64e-1)" "unprognostic (6.93e-2)" "unprognostic (6.00e-2)" "unprognostic (2.23e-1)" "unprognostic (1.70e-2)" "unprognostic (2.51e-1)" "unprognostic (4.02e-3)" "unprognostic (3.61e-2)" "unprognostic (8.11e-2)" "unprognostic (8.43e-3)" "unprognostic (5.47e-2)" "unprognostic (1.72e-1)" "unprognostic (1.24e-3)" "unprognostic (5.34e-2)" "potential prognostic unfavorable (8.94e-4)" "unprognostic (1.04e-3)" PLAGL2 ZNF900 ENSG00000126003 "PLAG1 like zinc finger 2" Q9UPG8 20 32192504-32207743 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 30.4" "Cell type enriched" "Detected in many" 4 "Late spermatids: 265.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "intermediate monocyte: 18.3;non-classical monocyte: 34.9" "Lineage enriched" "Detected in many" 15 "monocytes: 34.9" "Low cancer specificity" "Detected in all" "Kidney - Macrophages, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005900, HPA077084" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 16: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 36 Nucleoplasm Cytosol "HPA005900: , HPA077084: " "unprognostic (1.04e-2)" "unprognostic (1.04e-1)" "unprognostic (6.80e-3)" "unprognostic (2.12e-1)" "unprognostic (3.50e-2)" "unprognostic (3.10e-2)" "unprognostic (1.50e-1)" "unprognostic (2.60e-2)" "unprognostic (1.67e-1)" "unprognostic (2.19e-2)" "unprognostic (1.58e-2)" "unprognostic (2.20e-2)" "unprognostic (3.32e-2)" "potential prognostic unfavorable (6.49e-4)" "unprognostic (4.58e-3)" "unprognostic (1.34e-1)" "unprognostic (1.60e-2)" "unprognostic (2.14e-2)" "potential prognostic favorable (9.09e-6)" "unprognostic (1.99e-1)" "unprognostic (2.54e-1)" "unprognostic (1.96e-2)" "unprognostic (4.99e-2)" "unprognostic (1.35e-1)" "unprognostic (1.06e-3)" "unprognostic (8.11e-2)" "unprognostic (1.03e-1)" "unprognostic (6.62e-2)" "unprognostic (1.49e-1)" "unprognostic (2.46e-2)" "unprognostic (5.96e-2)" PLAT ENSG00000104368 "Plasminogen activator, tissue type" P00750 8 42174718-42207709 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Plasminogen activation" "Hydrolase, Protease, Serine protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 231.2;urinary bladder: 169.0" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 174.1;Breast hormone-responsive cells: 290.0;Decidual stromal cells: 229.7;Endometrial secretory cells: 233.7;Endometrial stromal cells: 147.2;Epididymal basal cells: 246.7;Esophageal apical cells: 177.9;Lymphatic endothelial cells: 177.3;Ocular epithelial cells: 500.1;Prostatic hillock cells: 476.0;Schwann cells: 164.6;Urothelial cells: 150.5;Vascular endothelial cells: 306.3" "Group enriched" "Detected in all" 4 "central nervous system macrophage: 78.9;endothelial cell: 233.4;oligodendrocyte precursor cell: 69.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 246.4" "Adrenal gland - Endothelial cells, Colon - Enteric glia cells, Kidney - Endothelial cells, Minor Salivary Gland - Endothelial cells, Prostate - Urothelial cells, Testis - Sertoli cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003412, CAB009335" Supported Approved "Actin filaments" "Secreted to blood" Enzyme NA NA 9900000 150000 "Cluster 69: Parathyroid gland - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 5 "Actin filaments" "CAB009335: , HPA003412: " "unprognostic (5.66e-2)" "unprognostic (1.15e-3)" "unprognostic (3.43e-2)" "unprognostic (6.21e-2)" "unprognostic (2.13e-1)" "unprognostic (5.50e-2)" "unprognostic (2.98e-2)" "unprognostic (2.49e-3)" "unprognostic (9.18e-2)" "unprognostic (2.57e-1)" "validated prognostic favorable (4.77e-4)" "validated prognostic favorable (7.71e-4)" "unprognostic (3.62e-2)" "unprognostic (2.86e-2)" "unprognostic (1.98e-3)" "unprognostic (1.25e-1)" "potential prognostic unfavorable (1.83e-4)" "unprognostic (1.34e-1)" "unprognostic (1.44e-1)" "unprognostic (3.74e-2)" "unprognostic (2.28e-2)" "unprognostic (5.11e-3)" "unprognostic (2.84e-1)" "unprognostic (4.16e-1)" "unprognostic (2.58e-1)" "unprognostic (8.58e-2)" "unprognostic (2.54e-1)" "unprognostic (3.97e-3)" "unprognostic (9.14e-2)" "unprognostic (1.97e-2)" "unprognostic (2.85e-1)" PLAU "UPA, URK" ENSG00000122861 "Plasminogen activator, urokinase" P00749 10 73909177-73917496 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis, Plasminogen activation" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 93.0;urinary bladder: 119.5" "Group enriched" "Detected in many" 5 "Epididymal basal cells: 1854.9;Ocular epithelial cells: 794.6" "Group enriched" "Detected in some" 6 "central nervous system macrophage: 13.3;fibroblast: 17.4;pericyte: 6.9;vascular associated smooth muscle cell: 9.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "myeloid DC: 1.1;neutrophil: 2.1;plasmacytoid DC: 2.0" "Group enriched" "Detected in many" 11 "dendritic cells: 2.0;granulocytes: 2.1" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 1199.2" "Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA070796 Supported Approved "Golgi apparatus,Vesicles" "Secreted to blood" "Blood coagulation" NA NA 647000 47000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 13 "Golgi apparatus, Vesicles" "HPA070796: " "unprognostic (4.73e-2)" "unprognostic (4.20e-2)" "unprognostic (7.35e-2)" "unprognostic (9.86e-3)" "unprognostic (2.67e-1)" "unprognostic (4.28e-2)" "unprognostic (2.54e-2)" "unprognostic (8.44e-3)" "potential prognostic unfavorable (2.39e-4)" "unprognostic (2.87e-2)" "unprognostic (3.89e-3)" "unprognostic (2.90e-2)" "unprognostic (2.69e-2)" "unprognostic (4.94e-3)" "unprognostic (1.68e-1)" "unprognostic (1.43e-2)" "potential prognostic unfavorable (4.46e-4)" "unprognostic (1.52e-3)" "unprognostic (3.07e-2)" "unprognostic (8.68e-3)" "unprognostic (1.11e-2)" "potential prognostic unfavorable (8.64e-5)" "unprognostic (1.67e-2)" "unprognostic (3.18e-1)" "unprognostic (1.97e-1)" "unprognostic (1.48e-2)" "unprognostic (1.04e-1)" "unprognostic (7.18e-2)" "unprognostic (1.81e-1)" "unprognostic (3.23e-2)" "unprognostic (5.85e-3)" PLAUR "CD87, UPAR, URKR" ENSG00000011422 "Plasminogen activator, urokinase receptor" Q03405 19 43646095-43670547 "Cancer-related genes, CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "bone marrow: 650.6" "Cell type enhanced" "Detected in many" "cDC: 1115.4;Endometrial glandular cells: 779.5;Endometrial secretory cells: 874.8;Epididymal basal cells: 3927.4;Macrophages: 787.2;monocytes: 2786.3;Neutrophils: 7137.8;Ocular epithelial cells: 2333.0;Urothelial cells: 779.3" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 39.5;leukocyte: 49.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1177.3" "Group enriched" "Detected in all" 4 "granulocytes: 1177.3;monocytes: 553.8" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Thyroid gland - Neutrophils" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA050843, CAB073533" Uncertain Supported "Plasma membrane" "Intracellular and membrane" Receptor NA NA 620000 "Cluster 7: Non-specific - Innate immune response" "Cluster 15: Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 72: Neuronal - Signal transduction" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 5 "Plasma membrane" "CAB073533: , HPA050843: " "unprognostic (1.01e-1)" "unprognostic (8.30e-2)" "unprognostic (2.27e-1)" "unprognostic (3.73e-3)" "unprognostic (1.43e-1)" "unprognostic (9.42e-2)" "unprognostic (1.67e-3)" "unprognostic (7.01e-3)" "unprognostic (9.80e-3)" "unprognostic (1.78e-1)" "potential prognostic unfavorable (1.24e-6)" "unprognostic (2.64e-2)" "unprognostic (2.51e-1)" "potential prognostic unfavorable (4.24e-5)" "unprognostic (1.64e-1)" "potential prognostic unfavorable (4.67e-4)" "unprognostic (3.24e-3)" "unprognostic (2.28e-2)" "unprognostic (7.06e-2)" "unprognostic (2.28e-3)" "unprognostic (1.57e-1)" "unprognostic (2.37e-3)" "unprognostic (9.71e-3)" "unprognostic (2.65e-1)" "unprognostic (1.10e-1)" "unprognostic (5.75e-3)" "unprognostic (1.52e-2)" "unprognostic (8.71e-2)" "unprognostic (6.56e-2)" "unprognostic (3.52e-2)" "unprognostic (6.37e-2)" PLB1 "FLJ30866, PLB" ENSG00000163803 "Phospholipase B1" Q6P1J6 2 28457145-28644142 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Phospholipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "intestine: 36.7" "Group enriched" "Detected in many" 4 "Enterocytes: 314.1;Neutrophils: 337.0" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 78.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 14 "classical monocyte: 3.0;eosinophil: 3.0;intermediate monocyte: 4.4;myeloid DC: 5.7;neutrophil: 8.9;non-classical monocyte: 5.0" "Group enriched" "Detected in many" 40 "dendritic cells: 5.7;granulocytes: 8.9;monocytes: 5.0" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Macrophages, Adrenal gland - Adrenal cortex cells, Kidney - Macrophages, Lung - Neutrophils_2, Skin - Hair cortex cells, Skin - Inner root sheath cells, Spleen - Neutrophils_2" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 33: Neurons - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" 1 "unprognostic (1.61e-1)" "unprognostic (2.39e-1)" "unprognostic (1.20e-1)" "unprognostic (5.69e-2)" "unprognostic (2.86e-1)" "unprognostic (6.71e-2)" "unprognostic (1.81e-2)" "unprognostic (5.47e-2)" "unprognostic (1.28e-1)" "unprognostic (9.07e-3)" "unprognostic (3.21e-1)" "unprognostic (9.14e-2)" "unprognostic (3.15e-1)" "unprognostic (5.60e-2)" "unprognostic (1.46e-2)" "unprognostic (1.10e-2)" "unprognostic (7.14e-2)" "unprognostic (2.48e-1)" "unprognostic (6.05e-2)" "unprognostic (9.88e-2)" "unprognostic (2.70e-1)" "unprognostic (3.12e-2)" "unprognostic (2.61e-1)" "unprognostic (1.88e-2)" "unprognostic (4.05e-2)" "unprognostic (9.57e-2)" PLBD1 FLJ22662 ENSG00000121316 "Phospholipase B domain containing 1" Q6P4A8 12 14503661-14567883 "Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 270.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 180.6;Esophageal apical cells: 691.2;Extravillous trophoblasts: 262.0;Monocyte progenitors: 197.1;monocytes: 301.2;Neutrophil progenitors: 1093.6;Neutrophils: 610.2;Urothelial cells: 172.7" "Group enriched" "Detected in many" 4 "central nervous system macrophage: 32.5;choroid plexus epithelial cell: 22.9;fibroblast: 26.5;leukocyte: 10.4;pericyte: 9.1" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 239.5" "Region enriched" "Detected in all" 6 "choroid plexus: 51.0" "Group enriched" "Detected in many" 6 "classical monocyte: 663.4;intermediate monocyte: 204.4;myeloid DC: 357.5;neutrophil: 445.2" "Group enriched" "Detected in all" 135 "dendritic cells: 357.5;granulocytes: 445.2;monocytes: 663.4" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Spleen - Neutrophils_2, Thyroid gland - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA040303 Enhanced "Intracellular and membrane" Enzyme NA NA 7900000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 15: Bone marrow - Innate immune response" "Cluster 8: Immune cells - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 34 "HPA040303: " "unprognostic (4.15e-3)" "unprognostic (2.69e-2)" "unprognostic (1.66e-2)" "unprognostic (2.29e-2)" "unprognostic (1.44e-1)" "unprognostic (1.29e-2)" "unprognostic (3.26e-3)" "potential prognostic unfavorable (2.84e-4)" "unprognostic (2.72e-2)" "unprognostic (5.17e-2)" "potential prognostic favorable (3.06e-4)" "unprognostic (1.31e-1)" "unprognostic (1.68e-3)" "potential prognostic unfavorable (3.85e-7)" "unprognostic (1.48e-2)" "unprognostic (5.27e-3)" "unprognostic (8.61e-2)" "unprognostic (3.48e-1)" "unprognostic (2.21e-1)" "unprognostic (1.33e-1)" "unprognostic (1.85e-1)" "potential prognostic unfavorable (5.60e-4)" "unprognostic (1.26e-1)" "unprognostic (1.57e-1)" "unprognostic (2.56e-2)" "unprognostic (1.47e-1)" "unprognostic (8.35e-2)" "unprognostic (4.06e-1)" "unprognostic (2.93e-1)" "unprognostic (1.04e-1)" "potential prognostic unfavorable (1.90e-5)" PLBD2 p76 ENSG00000151176 "Phospholipase B domain containing 2" Q8NHP8 12 113358566-113391629 "Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 130.6" "Cell type enriched" "Detected in many" 5 "Late spermatids: 848.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skin - Fibroblasts_1, Skin - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017163 Approved "Intracellular and membrane" Enzyme NA NA 640000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 45: Non-specific - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 6 "HPA017163: " "unprognostic (1.17e-2)" "unprognostic (1.11e-1)" "unprognostic (3.41e-1)" "unprognostic (1.15e-2)" "unprognostic (1.12e-1)" "unprognostic (2.29e-2)" "unprognostic (2.32e-2)" "unprognostic (3.16e-2)" "unprognostic (2.20e-2)" "unprognostic (2.09e-2)" "potential prognostic unfavorable (1.43e-4)" "unprognostic (2.57e-3)" "unprognostic (3.37e-2)" "unprognostic (1.14e-3)" "unprognostic (2.54e-2)" "unprognostic (3.59e-3)" "unprognostic (5.29e-2)" "unprognostic (1.70e-1)" "unprognostic (2.73e-1)" "unprognostic (1.26e-2)" "unprognostic (1.66e-2)" "unprognostic (4.49e-2)" "unprognostic (6.71e-2)" "unprognostic (2.55e-1)" "unprognostic (1.15e-3)" "unprognostic (8.28e-3)" "unprognostic (1.91e-1)" "unprognostic (2.87e-2)" "unprognostic (1.86e-1)" "unprognostic (2.96e-2)" "unprognostic (2.55e-1)" PLCB1 "KIAA0581, PLC-I, PLC154" ENSG00000182621 "Phospholipase C beta 1" Q9NQ66 20 8077251-8968360 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" Epilepsy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 44.7" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 1192.4;Brain inhibitory neurons: 2360.5;Lacrimal acinar cells: 2680.3;Loop of henle epithelial cells: 1861.2;Mesothelial cells: 1373.6;Retinal ganglion cells: 1560.6;Salivary acinar cells: 2855.7;Salivary myoepithelial cells: 1235.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Minor Salivary Gland - Minor salivary gland ductal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004275, CAB005334, HPA034743, HPA057910" Enhanced Approved "Plasma membrane" NA NA 3600 "Cluster 33: Non-specific - ATP binding" "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 9 "Plasma membrane" "CAB004275: , CAB005334: , HPA034743: , HPA057910: " "unprognostic (3.39e-2)" "unprognostic (5.25e-2)" "unprognostic (4.40e-2)" "unprognostic (1.92e-1)" "unprognostic (7.16e-2)" "unprognostic (1.64e-1)" "unprognostic (6.70e-2)" "unprognostic (1.69e-3)" "unprognostic (7.34e-2)" "unprognostic (7.45e-2)" "validated prognostic favorable (1.42e-5)" "validated prognostic favorable (9.16e-5)" "unprognostic (1.65e-1)" "validated prognostic unfavorable (1.64e-5)" "validated prognostic unfavorable (1.10e-4)" "unprognostic (1.55e-2)" "unprognostic (4.58e-2)" "unprognostic (1.23e-1)" "unprognostic (2.84e-1)" "unprognostic (2.21e-1)" "unprognostic (2.81e-1)" "unprognostic (3.36e-2)" "unprognostic (8.13e-2)" "unprognostic (9.83e-2)" "unprognostic (3.04e-2)" "unprognostic (4.71e-2)" "unprognostic (1.09e-1)" "unprognostic (6.68e-2)" "unprognostic (4.53e-2)" "unprognostic (5.43e-2)" "unprognostic (1.16e-1)" PLCB2 FLJ38135 ENSG00000137841 "Phospholipase C beta 2" Q00722 15 40278176-40307935 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 49.6;lymphoid tissue: 38.4" "Cell type enhanced" "Detected in many" "cDC: 57.5;Hofbauer cells: 46.5;Kupffer cells: 56.4;Macrophages: 45.3;Megakaryocytes: 49.5;Microglia: 109.5;Monocyte progenitors: 41.2;monocytes: 60.9;Neutrophil progenitors: 42.1;Neutrophils: 84.4;Tuft cells: 172.9" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 125.3;leukocyte: 47.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in many" 5 "Leukemia: 35.8" "Adrenal gland - Macrophages, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Liver - Kupffer cells, Prostate - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB009443, HPA041298, HPA068595, HPA069308" Enhanced Approved "Golgi apparatus,Plasma membrane,Basal body,Cytosol" NA NA 18000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 3 Cytosol "Golgi apparatus, Plasma membrane, Basal body" "CAB009443: , HPA041298: , HPA068595: , HPA069308: " "unprognostic (5.65e-2)" "unprognostic (1.79e-1)" "unprognostic (1.56e-2)" "unprognostic (6.58e-2)" "unprognostic (2.57e-1)" "unprognostic (3.38e-2)" "unprognostic (3.74e-1)" "unprognostic (1.99e-2)" "unprognostic (5.03e-3)" "unprognostic (2.37e-1)" "unprognostic (8.80e-2)" "unprognostic (4.01e-1)" "unprognostic (2.08e-2)" "unprognostic (1.10e-2)" "potential prognostic favorable (1.62e-4)" "unprognostic (1.04e-1)" "unprognostic (1.48e-1)" "unprognostic (3.54e-1)" "unprognostic (1.10e-1)" "unprognostic (7.61e-2)" "unprognostic (8.68e-2)" "unprognostic (1.36e-2)" "unprognostic (2.17e-1)" "unprognostic (7.52e-3)" "unprognostic (2.46e-1)" "unprognostic (2.49e-1)" "unprognostic (8.40e-2)" "unprognostic (3.36e-2)" "unprognostic (3.06e-1)" "unprognostic (1.29e-1)" PLCB3 ENSG00000149782 "Phospholipase C beta 3" Q01970 11 64251530-64269150 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 107.1" "Cell type enhanced" "Detected in many" "Colonocytes: 47.9;Enteric stem cells: 48.6;Enteric transient amplifying cells: 84.9;Enterocytes: 159.2;Esophageal apical cells: 67.5;Paneth cells: 65.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.2" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009257, HPA039279, HPA043907" Enhanced Supported "Nucleoplasm,Golgi apparatus" NA NA 140000 "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 1: Enterocytes - Absorption and Digestion" 30 "Nucleoplasm, Golgi apparatus" "CAB009257: , HPA039279: , HPA043907: " "unprognostic (6.33e-2)" "unprognostic (5.73e-2)" "unprognostic (6.59e-2)" "unprognostic (4.68e-3)" "unprognostic (1.77e-1)" "unprognostic (8.72e-2)" "unprognostic (6.28e-2)" "unprognostic (1.98e-1)" "unprognostic (4.78e-3)" "unprognostic (2.81e-2)" "unprognostic (3.61e-1)" "unprognostic (1.81e-1)" "unprognostic (3.20e-2)" "potential prognostic unfavorable (1.67e-4)" "unprognostic (7.56e-2)" "unprognostic (5.79e-3)" "potential prognostic unfavorable (2.23e-4)" "unprognostic (1.32e-1)" "unprognostic (2.16e-1)" "unprognostic (9.18e-2)" "unprognostic (1.19e-1)" "unprognostic (9.83e-3)" "unprognostic (1.47e-2)" "unprognostic (2.01e-2)" "unprognostic (2.24e-2)" "unprognostic (6.49e-2)" "unprognostic (2.29e-2)" "unprognostic (1.00e-2)" "unprognostic (3.04e-1)" "unprognostic (1.05e-1)" "unprognostic (3.81e-1)" PLCB4 ENSG00000101333 "Phospholipase C beta 4" Q15147 20 9067825-9504593 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 47.7" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 659.5;Choroid plexus epithelial cells: 1249.2;Pituitary stem cells: 699.6;Retinal amacrine cells: 668.2;Retinal bipolar cells: 674.0;Retinal horizontal cells: 1170.0;Salivary acinar cells: 1050.7;Thyrotrophs: 683.8" "Cell type enhanced" "Detected in all" "pericyte: 1570.4" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 38.5;Rectum Adenocarcinoma (TCGA): 46.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 1.8;plasmacytoid DC: 2.0" "Group enriched" "Detected in many" 4 "dendritic cells: 2.0;granulocytes: 1.8" "Cancer enhanced" "Detected in many" "Kidney cancer: 60.0" "Adipose subcutaneous - Smooth muscle cells, Liver - Hepatic stellate cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007951 Approved Uncertain "Nucleoplasm,Plasma membrane,Actin filaments,Microtubules,Cytokinetic bridge,Primary cilium,Centrosome,Basal body,Acrosome,Equatorial segment,Mid piece,Principal piece,End piece" Yes NA 2900 "Cluster 2: Dendritic cells - Unknown function" "Cluster 60: Stomach - Digestion" "Cluster 25: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 1 "Plasma membrane, Microtubules, Primary cilium, Basal body" "Nucleoplasm, Actin filaments, Cytokinetic bridge, Centrosome, Acrosome, Equatorial segment, Mid piece, Principal piece, End piece" "HPA007951: " "unprognostic (6.71e-2)" "unprognostic (6.96e-2)" "unprognostic (9.74e-3)" "unprognostic (3.02e-1)" "unprognostic (1.08e-2)" "unprognostic (1.19e-1)" "unprognostic (1.49e-1)" "potential prognostic favorable (6.41e-4)" "unprognostic (1.65e-2)" "unprognostic (1.37e-2)" "unprognostic (7.69e-2)" "unprognostic (3.02e-2)" "unprognostic (3.16e-3)" "unprognostic (1.00e-1)" "unprognostic (3.55e-1)" "unprognostic (3.13e-2)" "unprognostic (8.98e-2)" "potential prognostic favorable (9.82e-4)" "unprognostic (2.83e-1)" "unprognostic (2.43e-2)" "unprognostic (3.54e-2)" "unprognostic (2.28e-3)" "unprognostic (2.21e-1)" "unprognostic (2.01e-3)" "unprognostic (1.76e-1)" "unprognostic (2.95e-1)" "unprognostic (6.28e-2)" "unprognostic (3.73e-2)" "unprognostic (9.80e-2)" "unprognostic (1.65e-1)" PLCD1 ENSG00000187091 "Phospholipase C delta 1" P51178 3 38007496-38029642 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 74.8;Esophageal apical cells: 94.6;Esophageal suprabasal cells: 66.6;Goblet cells: 55.0;Sertoli cells: 88.8;Urothelial cells: 53.2" "Cell type enhanced" "Detected in many" "astrocyte: 47.4;Bergmann glia: 35.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009913, HPA020107, HPA021677" Approved Approved Microtubules NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 74: Non-specific - Signal transduction" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 16 Microtubules "CAB009913: , HPA020107: , HPA021677: " "unprognostic (1.66e-1)" "unprognostic (1.92e-3)" "unprognostic (1.08e-3)" "unprognostic (1.51e-1)" "unprognostic (2.10e-2)" "unprognostic (1.45e-1)" "unprognostic (3.35e-1)" "unprognostic (1.49e-1)" "unprognostic (5.36e-2)" "unprognostic (1.56e-1)" "validated prognostic favorable (6.78e-6)" "validated prognostic favorable (9.75e-4)" "unprognostic (7.46e-3)" "unprognostic (2.21e-1)" "unprognostic (3.13e-2)" "unprognostic (1.11e-2)" "unprognostic (1.49e-1)" "unprognostic (3.47e-2)" "unprognostic (3.46e-1)" "unprognostic (1.03e-1)" "unprognostic (8.40e-2)" "unprognostic (4.81e-2)" "unprognostic (1.49e-1)" "unprognostic (1.01e-1)" "unprognostic (1.16e-1)" "unprognostic (1.06e-1)" "unprognostic (6.22e-2)" "unprognostic (2.91e-1)" "unprognostic (1.79e-1)" "unprognostic (1.02e-1)" "unprognostic (1.02e-1)" PLCD3 ENSG00000161714 "Phospholipase C delta 3" Q8N3E9 17 45108959-45133354 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 80.4" "Cell type enhanced" "Detected in many" "Colonocytes: 160.3;Esophageal apical cells: 52.4;Foveolar cells: 97.6;Prostatic hillock cells: 58.9;Urothelial cells: 151.0" "Cell type enhanced" "Detected in many" "astrocyte: 67.5;ependymal cell: 41.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Skin - Keratinocyte (granular), Spleen - Fibroblasts_2, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025711, HPA053665" Approved Approved "Plasma membrane" NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 69: Urothelial cells - Basic cellular functions" 21 "Plasma membrane" "HPA025711: , HPA053665: " "potential prognostic favorable (4.33e-4)" "unprognostic (1.43e-2)" "unprognostic (2.68e-1)" "unprognostic (3.99e-2)" "unprognostic (5.02e-2)" "unprognostic (1.59e-2)" "unprognostic (3.55e-1)" "unprognostic (1.94e-1)" "unprognostic (3.08e-2)" "unprognostic (9.95e-3)" "unprognostic (5.10e-3)" "unprognostic (1.64e-1)" "unprognostic (2.93e-3)" "unprognostic (3.03e-3)" "unprognostic (9.68e-2)" "potential prognostic unfavorable (1.88e-7)" "unprognostic (4.59e-2)" "unprognostic (4.70e-2)" "unprognostic (2.43e-1)" "unprognostic (1.60e-2)" "unprognostic (1.38e-2)" "unprognostic (1.07e-3)" "unprognostic (3.51e-1)" "unprognostic (4.49e-2)" "unprognostic (6.91e-2)" "unprognostic (8.69e-2)" "unprognostic (1.82e-1)" "unprognostic (9.38e-2)" "unprognostic (1.21e-1)" "unprognostic (2.55e-3)" "unprognostic (8.81e-2)" PLCD4 ENSG00000115556 "Phospholipase C delta 4" Q9BRC7 2 218607855-218637184 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Guanine-nucleotide releasing factor, Hydrolase, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "retina: 153.9;skeletal muscle: 106.9" "Group enriched" "Detected in many" 5 "Cone photoreceptor cells: 296.0;Myonuclei: 370.6;Retinal bipolar cells: 300.4;Rod photoreceptor cells: 311.7" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 9.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 3.8;Rhabdoid: 5.0" "Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009914, HPA038139, HPA038140" Enhanced Supported "Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 2 Cytosol "Endoplasmic reticulum, Plasma membrane" "CAB009914: , HPA038139: , HPA038140: " "unprognostic (1.30e-1)" "unprognostic (5.02e-2)" "unprognostic (1.23e-1)" "potential prognostic favorable (9.74e-4)" "unprognostic (2.52e-1)" "unprognostic (7.82e-3)" "unprognostic (1.46e-1)" "unprognostic (3.52e-2)" "unprognostic (4.41e-2)" "unprognostic (2.39e-2)" "potential prognostic unfavorable (8.65e-4)" PLCE1 "KIAA1516, NPHS3, PLCE" ENSG00000138193 "Phospholipase C epsilon 1" Q9P212 10 93993931-94332823 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" "Guanine-nucleotide releasing factor, Hydrolase, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 5 "Podocytes: 2511.8" "Cell type enhanced" "Detected in all" "pericyte: 715.0;vascular associated smooth muscle cell: 658.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Podocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA015597, HPA015598" Enhanced Supported Cytosol NA NA "Cluster 34: B-cells - Unknown function" "Cluster 60: Stomach - Digestion" "Cluster 46: Brainstem - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 57: Podocytes - Glomerular filtration" 1 Cytosol "HPA015597: , HPA015598: " "unprognostic (8.34e-3)" "unprognostic (5.16e-2)" "unprognostic (2.51e-1)" "unprognostic (9.74e-2)" "unprognostic (1.43e-1)" "unprognostic (1.21e-1)" "unprognostic (2.85e-1)" "unprognostic (1.47e-1)" "unprognostic (1.53e-1)" "unprognostic (9.38e-2)" "unprognostic (1.67e-1)" "unprognostic (1.52e-2)" "unprognostic (1.70e-2)" "unprognostic (1.21e-2)" "unprognostic (1.51e-1)" "unprognostic (9.45e-2)" "unprognostic (4.11e-1)" "unprognostic (1.37e-1)" "unprognostic (4.26e-2)" "unprognostic (2.68e-1)" "unprognostic (4.93e-3)" "unprognostic (1.14e-1)" "unprognostic (2.68e-1)" "unprognostic (3.81e-1)" "unprognostic (1.07e-1)" "unprognostic (1.88e-1)" "unprognostic (1.78e-1)" "unprognostic (4.55e-2)" "unprognostic (7.16e-2)" "unprognostic (1.25e-1)" "unprognostic (2.35e-2)" PLCG1 "NCKAP3, PLC-II, PLC1, PLC148, PLCgamma1" ENSG00000124181 "Phospholipase C gamma 1" P19174 20 41136960-41196801 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Host-virus interaction, Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 94.6;Bergmann glia: 87.7;Cardiomyocytes: 117.3;Epicardial cells: 261.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "gdT-cell: 4.7;MAIT T-cell: 6.4;memory CD4 T-cell: 4.1;memory CD8 T-cell: 3.9;naive CD4 T-cell: 4.3;naive CD8 T-cell: 4.3;NK-cell: 3.4;T-reg: 3.8" "Group enriched" "Detected in many" 9 "NK-cells: 3.4;T-cells: 6.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004277, HPA036681, HPA036682" Approved Supported "Plasma membrane,Basal body,Cytosol" NA NA 10000 "Cluster 1: T-cells - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 85 "Plasma membrane" "Basal body, Cytosol" "CAB004277: , HPA036681: , HPA036682: " "unprognostic (1.77e-3)" "unprognostic (3.60e-2)" "unprognostic (8.47e-2)" "unprognostic (7.77e-3)" "unprognostic (1.45e-1)" "unprognostic (3.03e-1)" "unprognostic (8.87e-2)" "unprognostic (2.11e-1)" "unprognostic (4.87e-2)" "unprognostic (3.66e-3)" "unprognostic (1.72e-2)" "unprognostic (9.73e-2)" "unprognostic (5.83e-2)" "potential prognostic unfavorable (8.79e-4)" "unprognostic (7.29e-2)" "unprognostic (6.43e-3)" "unprognostic (2.14e-2)" "unprognostic (1.05e-1)" "unprognostic (1.61e-2)" "unprognostic (1.01e-1)" "unprognostic (2.99e-1)" "unprognostic (1.43e-3)" "unprognostic (5.79e-3)" "unprognostic (3.41e-1)" "unprognostic (3.67e-2)" "unprognostic (6.36e-3)" "unprognostic (6.26e-3)" "unprognostic (2.24e-1)" "unprognostic (4.43e-1)" "unprognostic (6.01e-2)" "unprognostic (2.42e-1)" PLCG2 ENSG00000197943 "Phospholipase C gamma 2" P16885 16 81779279-81962685 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 42.3" "Cell type enhanced" "Detected in many" "B-cells: 96.3;Distal convoluted tubule cells: 218.4;Loop of henle epithelial cells: 91.7;Microglia: 346.3;Podocytes: 539.4;Proximal tubule cells: 100.6;Renal collecting duct intercalated cells: 1099.2;Renal collecting duct principal cells: 149.9;Renal connecting tubule cells: 195.3;Tuft cells: 115.3" "Group enriched" "Detected in many" 7 "central nervous system macrophage: 427.3;endothelial cell: 158.6;leukocyte: 164.5" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 246.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 7 "Leukemia: 28.1;lymphoma: 88.4;Myeloma: 29.1" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Kidney - Intercalated cells, Prostate - Endothelial cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB004280, HPA020099, HPA020100" Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA 20000 "Cluster 14: Non-specific - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 27 "Vesicles, Cytosol" Nucleoplasm "CAB004280: , HPA020099: , HPA020100: " "unprognostic (2.29e-1)" "unprognostic (6.83e-2)" "unprognostic (1.04e-2)" "unprognostic (6.26e-2)" "unprognostic (2.34e-1)" "unprognostic (1.90e-3)" "unprognostic (7.51e-2)" "unprognostic (1.17e-1)" "potential prognostic favorable (7.20e-4)" "unprognostic (8.47e-2)" "potential prognostic favorable (9.03e-9)" "unprognostic (2.83e-3)" "potential prognostic unfavorable (4.92e-4)" "unprognostic (1.18e-1)" "potential prognostic favorable (3.98e-4)" "unprognostic (7.59e-3)" "unprognostic (7.38e-2)" "unprognostic (1.99e-2)" "unprognostic (1.41e-1)" "unprognostic (1.98e-1)" "unprognostic (1.28e-1)" "unprognostic (2.92e-2)" "unprognostic (3.55e-3)" "unprognostic (9.65e-2)" "unprognostic (1.72e-1)" "unprognostic (4.34e-2)" "unprognostic (1.21e-1)" "unprognostic (3.00e-1)" "unprognostic (1.44e-2)" "unprognostic (1.49e-1)" "unprognostic (6.89e-2)" PLCH1 "DKFZp434C1372, KIAA1069, MGC117152, PLCeta1, PLCL3" ENSG00000114805 "Phospholipase C eta 1" Q4KWH8 3 155375580-155745071 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Disease variant, Holoprosencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 15.5;retina: 11.5;testis: 10.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 238.0;Bergmann glia: 449.3;Choroid plexus epithelial cells: 397.9;Early spermatids: 238.2;Endometrial ciliated cells: 347.4;Ependymal cells: 496.1;Fallopian tube ciliated cells: 257.8;Pituicytes/FSCs: 439.3;Pituitary stem cells: 315.9;Respiratory ciliated cells: 495.4;Retinal amacrine cells: 419.3;Retinal horizontal cells: 234.4;Sertoli cells: 246.2" "Cell type enhanced" "Detected in all" "cerebellar inhibitory: 665.2;ependymal cell: 538.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Leukemia: 9.6" "Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary gland ductal cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036176, HPA057978" Uncertain Enhanced Vesicles NA NA "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 23: Choroid plexus - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 18 Vesicles "HPA036176: , HPA057978: " "unprognostic (3.76e-1)" "unprognostic (7.86e-3)" "unprognostic (1.92e-1)" "unprognostic (4.77e-1)" "unprognostic (5.20e-2)" "unprognostic (7.78e-2)" "potential prognostic unfavorable (2.18e-4)" "unprognostic (1.45e-2)" "unprognostic (7.94e-2)" "potential prognostic favorable (2.29e-4)" "unprognostic (1.66e-2)" "potential prognostic favorable (4.89e-4)" "unprognostic (3.67e-2)" "unprognostic (2.22e-1)" "unprognostic (1.37e-1)" "unprognostic (6.22e-3)" "unprognostic (1.60e-2)" "unprognostic (1.63e-3)" "unprognostic (3.42e-2)" "unprognostic (4.32e-3)" "unprognostic (2.16e-2)" "unprognostic (3.52e-2)" "unprognostic (1.58e-2)" "unprognostic (1.18e-1)" "unprognostic (1.48e-1)" "unprognostic (1.05e-1)" PLCH2 "KIAA0450, PLC-eta2, PLCeta2, PLCL4, RP3-395M20.1" ENSG00000149527 "Phospholipase C eta 2" O75038 1 2425980-2505532 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 69.5;retina: 41.6;skin 1: 56.9" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 29.2;Brain inhibitory neurons: 23.0;Oligodendrocytes: 36.0;Other brain neurons: 12.9;Papillary tip epithelial cells: 20.8;Proximal tubule cells: 27.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 14.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 17.9;head and neck cancer: 22.4" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - Breast myoepithelial cells, Heart muscle - T-cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072705 Enhanced NA NA "Cluster 2: Non-specific - Mixed function" "Cluster 25: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 88: Proximal tubular cells - Transmembrane transport" "HPA072705: " "unprognostic (1.32e-2)" "unprognostic (1.44e-1)" "unprognostic (1.66e-1)" "unprognostic (8.49e-2)" "unprognostic (9.06e-3)" "unprognostic (4.01e-2)" "potential prognostic favorable (3.18e-4)" "unprognostic (4.77e-3)" "unprognostic (2.88e-2)" "potential prognostic favorable (1.35e-5)" "unprognostic (6.32e-2)" "unprognostic (2.20e-1)" "unprognostic (1.54e-1)" "unprognostic (2.94e-1)" "unprognostic (2.84e-1)" "unprognostic (6.09e-2)" "unprognostic (9.73e-3)" "unprognostic (5.38e-2)" "unprognostic (2.43e-2)" "unprognostic (6.16e-2)" "unprognostic (7.91e-3)" "unprognostic (5.59e-2)" PLCL1 "PLC-L, PLCE, PLCL, PPP1R127, PRIP" ENSG00000115896 "Phospholipase C like 1 (inactive)" Q15111 2 197804593-198572581 "Predicted intracellular proteins" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 38.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 1222.6;Choroid plexus epithelial cells: 1513.6;Decidual stromal cells: 843.4;Distal convoluted tubule cells: 2270.6;Endometrial stromal cells: 1975.1;Loop of henle epithelial cells: 1132.6;Neutrophils: 856.8;Oligodendrocytes: 2120.8;Pituicytes/FSCs: 1900.6;Proximal tubule cells: 804.9;Renal collecting duct intercalated cells: 1873.5;Retinal pigment epithelial cells: 1295.9" "Cell type enhanced" "Detected in all" "oligodendrocyte: 3101.5" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 8.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.4" "Lineage enriched" "Detected in single" 6 "T-cells: 1.4" "Cancer enhanced" "Detected in some" "Neuroblastoma: 2.3;Rhabdoid: 2.3" "Adipose visceral - Mesothelial cells, Liver - Hepatic stellate cells, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031849 Enhanced NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" "HPA031849: " "unprognostic (3.39e-2)" "unprognostic (3.18e-2)" "unprognostic (2.01e-1)" "unprognostic (1.85e-1)" "unprognostic (1.84e-3)" "unprognostic (1.72e-1)" "validated prognostic favorable (1.54e-9)" "validated prognostic favorable (2.95e-4)" "unprognostic (1.44e-2)" "unprognostic (1.60e-1)" "unprognostic (5.46e-2)" "unprognostic (5.64e-1)" "unprognostic (3.27e-1)" "unprognostic (5.38e-3)" "unprognostic (7.64e-2)" "potential prognostic unfavorable (2.72e-4)" "unprognostic (1.25e-1)" "unprognostic (5.58e-2)" PLCL2 "KIAA1092, PLCE2" ENSG00000154822 "Phospholipase C like 2" Q9UPR0 3 16802651-17090604 "Predicted intracellular proteins" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 25.8" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 255.0;Brain inhibitory neurons: 286.9;Distal convoluted tubule cells: 97.7;Microglia: 495.4;Oligodendrocyte progenitor cells: 147.4;Oligodendrocytes: 119.9;Other brain neurons: 118.8;Podocytes: 144.0;Proximal tubule cells: 153.1;Renal collecting duct intercalated cells: 317.2;Renal collecting duct principal cells: 368.6;Renal connecting tubule cells: 124.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 10.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Leukemia: 5.6;lymphoma: 12.0;Myeloma: 9.4" "Adrenal gland - Adrenal cortex cells, Breast - Fibroblasts, Heart muscle - Cardiomyocytes, Pituitary gland - Lactotropes, Prostate - Fibroblasts, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047616, HPA061728" Enhanced NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 24: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 102: Non-specific - Mixed function" 8 "HPA047616: , HPA061728: " "unprognostic (7.73e-2)" "unprognostic (6.39e-2)" "unprognostic (1.60e-2)" "unprognostic (5.74e-2)" "unprognostic (1.43e-1)" "unprognostic (7.94e-2)" "unprognostic (2.13e-1)" "unprognostic (3.21e-2)" "unprognostic (1.39e-1)" "validated prognostic favorable (4.24e-9)" "validated prognostic favorable (5.31e-5)" "unprognostic (3.87e-2)" "unprognostic (1.67e-1)" "unprognostic (1.00e-2)" "unprognostic (3.53e-2)" "unprognostic (9.53e-2)" "unprognostic (1.53e-1)" "unprognostic (6.08e-2)" "unprognostic (1.26e-1)" "unprognostic (9.41e-2)" "unprognostic (7.94e-3)" "unprognostic (1.96e-1)" "unprognostic (9.08e-3)" "unprognostic (8.84e-2)" "unprognostic (1.62e-1)" "unprognostic (1.17e-1)" "unprognostic (8.44e-2)" "unprognostic (9.74e-2)" PLCXD1 FLJ11323 ENSG00000182378 "Phosphatidylinositol specific phospholipase C X domain containing 1" Q9NUJ7 X 276322-303356 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 78.0;Esophageal apical cells: 178.8;Foveolar cells: 110.2;Megakaryocyte-Erythroid progenitors: 87.2;monocytes: 59.4;Syncytiotrophoblasts: 48.4" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA007721 Approved Approved Cytosol NA Yes "Cluster 40: Monocytes - Innate immune response" "Cluster 64: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 1 Cytosol "HPA007721: " "unprognostic (1.49e-1)" "unprognostic (3.89e-2)" "unprognostic (1.34e-1)" "unprognostic (1.49e-1)" "unprognostic (9.69e-2)" "unprognostic (2.63e-1)" "unprognostic (7.86e-2)" "potential prognostic favorable (7.45e-4)" "unprognostic (4.59e-3)" "potential prognostic unfavorable (3.89e-4)" "unprognostic (1.68e-1)" "unprognostic (1.54e-1)" "unprognostic (1.11e-3)" "unprognostic (8.73e-2)" "unprognostic (3.59e-1)" "unprognostic (1.33e-1)" "unprognostic (2.66e-2)" "unprognostic (7.48e-2)" "unprognostic (6.41e-2)" "unprognostic (1.55e-1)" "unprognostic (4.59e-2)" "potential prognostic unfavorable (1.69e-4)" "unprognostic (2.97e-2)" "unprognostic (2.12e-1)" "unprognostic (1.78e-3)" "unprognostic (1.54e-1)" "unprognostic (3.68e-1)" "unprognostic (2.53e-2)" "unprognostic (2.01e-1)" PLCXD2 FLJ31579 ENSG00000240891 "Phosphatidylinositol specific phospholipase C X domain containing 2" Q0VAA5 3 111674676-111846447 "Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "retina: 13.7" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 60.0;Epididymal clear cells: 53.1;Hepatocytes: 160.0;Neuroendocrine cells: 39.8;NK-cells: 54.7;Parietal cells: 155.6;Retinal horizontal cells: 40.1;Rod photoreceptor cells: 54.0;T-cells: 42.9" "Cell type enhanced" "Detected in many" "deep-layer corticothalamic and 6b: 41.7;deep-layer near-projecting: 41.4;leukocyte: 53.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 3.8" "Group enriched" "Detected in many" 5 "dendritic cells: 3.8;NK-cells: 1.1;T-cells: 1.8" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Corticotropes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055947 Uncertain Approved Nucleoplasm NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 72: Neuronal - Signal transduction" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 1 Nucleoplasm "HPA055947: " "unprognostic (3.80e-2)" "unprognostic (3.67e-1)" "unprognostic (2.01e-2)" "potential prognostic favorable (6.92e-5)" "unprognostic (2.65e-2)" "unprognostic (4.23e-2)" "unprognostic (3.14e-2)" "unprognostic (1.49e-1)" "unprognostic (9.04e-3)" "potential prognostic unfavorable (2.37e-4)" "unprognostic (1.54e-2)" "unprognostic (9.38e-2)" "unprognostic (1.30e-2)" PLCXD3 ENSG00000182836 "Phosphatidylinositol specific phospholipase C X domain containing 3" Q63HM9 5 41306952-41510628 "Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.6;heart muscle: 31.0;ovary: 26.4" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 319.1;Brain excitatory neurons: 161.7;Brain inhibitory neurons: 151.0;Cardiomyocytes: 694.2;Endometrial stromal cells: 266.1;Lactotrophs: 447.5;Neuroendocrine cells: 179.6;Ovarian stromal cells: 302.8;Pancreatic islet cells: 325.5;Pituitary stem cells: 191.2;Somatotrophs: 393.4;Thyrotrophs: 239.3;Vascular endothelial cells: 148.3" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Kidney Chromophobe (TCGA): 8.1;Pancreatic Adenocarcinoma (TCGA): 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 6.5" "Adrenal gland - Fibroblasts, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046849 Uncertain Approved "Golgi apparatus" NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 25: Non-specific - Transcription" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 2 "Golgi apparatus" "HPA046849: " "unprognostic (1.76e-1)" "unprognostic (1.23e-2)" "unprognostic (5.43e-2)" "unprognostic (3.11e-3)" "unprognostic (7.14e-2)" "unprognostic (1.89e-2)" "unprognostic (1.53e-1)" PLCZ1 "NYD-SP27, PLCzeta" ENSG00000139151 "Phospholipase C zeta 1" Q86YW0 12 18683169-18738100 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fertilization, Lipid degradation, Lipid metabolism" "Developmental protein, Hydrolase, Transducer" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 24 "testis: 39.9" "Group enriched" "Detected in some" 16 "Early spermatids: 820.7;Late primary spermatocytes: 277.8;Late spermatids: 454.7" "Cell type enriched" "Detected in some" 4 "ependymal cell: 26.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Region enhanced" "Detected in some" "amygdala: 3.1" "Not detected" "Not detected" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 39: Astrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" PLD1 ENSG00000075651 "Phospholipase D1" Q13393 3 171600404-171810950 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 81.4" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 489.9;Esophageal apical cells: 372.2;Esophageal suprabasal cells: 394.7;Fibro-adipogenic progenitors: 357.0;Neutrophil progenitors: 500.1;Oligodendrocytes: 577.1" "Group enriched" "Detected in many" 4 "central nervous system macrophage: 329.2;committed oligodendrocyte precursor: 372.0;fibroblast: 598.4;oligodendrocyte: 747.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 7.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Fibroblasts, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004527, HPA013555, HPA042396" Enhanced Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 77: Intestine - Digestion" "Cluster 11: White matter - Signal transduction" "Cluster 5: Rhabdoid - Unknown function" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 30 "Plasma membrane" "Golgi apparatus, Vesicles" "CAB004527: , HPA013555: , HPA042396: " "unprognostic (4.18e-2)" "unprognostic (1.29e-1)" "unprognostic (1.43e-2)" "unprognostic (3.00e-1)" "unprognostic (1.04e-1)" "unprognostic (2.95e-2)" "unprognostic (3.36e-1)" "unprognostic (5.64e-2)" "unprognostic (1.28e-1)" "unprognostic (6.93e-3)" "potential prognostic favorable (1.66e-4)" "unprognostic (1.46e-2)" "unprognostic (3.16e-1)" "unprognostic (7.95e-2)" "unprognostic (2.56e-2)" "unprognostic (4.02e-2)" "unprognostic (4.88e-2)" "unprognostic (7.08e-2)" "unprognostic (1.64e-3)" "unprognostic (4.62e-2)" "unprognostic (2.65e-1)" "unprognostic (7.67e-2)" "unprognostic (2.26e-1)" "unprognostic (1.15e-1)" "unprognostic (7.27e-2)" "unprognostic (1.50e-1)" "unprognostic (7.78e-2)" "unprognostic (8.21e-2)" "unprognostic (3.26e-1)" "unprognostic (7.11e-2)" "unprognostic (4.43e-1)" PLD2 ENSG00000129219 "Phospholipase D2" O14939 17 4807152-4823434 "Enzymes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 62.1" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 149.7;Esophageal suprabasal cells: 50.6" "Cell type enhanced" "Detected in many" "astrocyte: 38.4;Bergmann glia: 29.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013397 Approved NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 44: Non-specific - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 22 "HPA013397: " "unprognostic (3.23e-1)" "unprognostic (2.46e-1)" "unprognostic (4.09e-1)" "unprognostic (1.00e-2)" "unprognostic (1.66e-1)" "unprognostic (9.17e-3)" "unprognostic (2.54e-1)" "unprognostic (1.98e-1)" "unprognostic (6.15e-2)" "unprognostic (2.97e-2)" "unprognostic (3.59e-3)" "unprognostic (1.04e-1)" "unprognostic (5.95e-3)" "unprognostic (2.94e-3)" "unprognostic (1.15e-2)" "unprognostic (7.44e-2)" "unprognostic (2.24e-1)" "unprognostic (1.14e-1)" "unprognostic (8.30e-3)" "potential prognostic unfavorable (1.07e-4)" "unprognostic (6.75e-2)" "unprognostic (2.86e-1)" "unprognostic (8.16e-3)" "unprognostic (2.35e-2)" "unprognostic (2.06e-1)" "unprognostic (1.31e-1)" "unprognostic (2.78e-2)" "unprognostic (9.75e-2)" "unprognostic (2.12e-1)" "unprognostic (2.90e-3)" "unprognostic (2.68e-1)" PLD3 HU-K4 ENSG00000105223 "Phospholipase D family member 3" Q8IV08 19 40348456-40389472 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response, Lipid metabolism, Phospholipid metabolism" "Exonuclease, Hydrolase, Nuclease" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pituitary gland: 672.4" "Cell type enhanced" "Detected in all" "Gonadotrophs: 902.1;Hofbauer cells: 671.9;Kupffer cells: 416.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "basophil: 1768.4" "Lineage enriched" "Detected in all" 7 "granulocytes: 1768.4" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Breast - Fibroblasts, Colon - Fibroblasts, Pituitary gland - Gonadotropes, Spleen - Macrophages, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012800, CAB020812" Approved Approved "Nucleoplasm,Endoplasmic reticulum,Cytosol" NA NA 290000 "Cluster 41: Basophils - Unknown function" "Cluster 20: Pituitary gland - Hormone signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 26 "Endoplasmic reticulum, Cytosol" Nucleoplasm "CAB020812: , HPA012800: " "unprognostic (9.47e-3)" "unprognostic (3.25e-1)" "unprognostic (2.83e-1)" "unprognostic (5.86e-3)" "unprognostic (6.77e-2)" "unprognostic (4.86e-2)" "unprognostic (7.83e-3)" "unprognostic (2.63e-3)" "unprognostic (1.06e-1)" "unprognostic (1.45e-1)" "potential prognostic favorable (1.14e-5)" "unprognostic (2.39e-2)" "unprognostic (4.64e-2)" "unprognostic (3.12e-2)" "unprognostic (1.70e-1)" "unprognostic (5.44e-3)" "unprognostic (1.70e-2)" "unprognostic (1.68e-1)" "unprognostic (1.68e-1)" "unprognostic (1.53e-1)" "unprognostic (1.90e-1)" "unprognostic (3.48e-3)" "unprognostic (3.81e-1)" "unprognostic (3.22e-1)" "unprognostic (5.58e-2)" "unprognostic (6.51e-2)" "unprognostic (9.02e-2)" "unprognostic (2.78e-2)" "unprognostic (1.18e-1)" "unprognostic (8.83e-2)" "unprognostic (1.58e-2)" PLD4 C14orf175 ENSG00000166428 "Phospholipase D family member 4" Q96BZ4 14 104924713-104937761 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity, Lipid metabolism, Phospholipid metabolism" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 12.6;brain: 18.2;lymphoid tissue: 10.6" "Cell type enriched" "Detected in some" 4 "pDCs: 615.6" "Cell type enriched" "Detected in some" 28 "central nervous system macrophage: 150.2" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 25.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "plasmacytoid DC: 3628.5" "Lineage enriched" "Detected in all" 5 "dendritic cells: 3628.5" "Group enriched" "Detected in some" 77 "Leukemia: 34.7;lymphoma: 37.2;Myeloma: 37.5" "Adipose visceral - T-cells, Prostate - T-cells, Skin - Langerhans cells, Spleen - B-cells (Spleen), Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051512 Uncertain NA NA 2600000 "Cluster 29: Non-specific - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 43: Hindbrain - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 5 "HPA051512: " "unprognostic (1.16e-1)" "unprognostic (4.88e-3)" "unprognostic (6.33e-2)" "potential prognostic favorable (1.81e-4)" "unprognostic (1.50e-1)" "unprognostic (2.54e-1)" "unprognostic (1.25e-2)" "unprognostic (1.04e-2)" "potential prognostic favorable (8.97e-5)" "unprognostic (4.24e-2)" "unprognostic (4.41e-3)" "unprognostic (6.59e-2)" "unprognostic (1.13e-2)" "unprognostic (3.31e-1)" "unprognostic (9.21e-2)" "potential prognostic favorable (4.42e-4)" "unprognostic (9.11e-2)" "unprognostic (2.16e-1)" "unprognostic (2.87e-1)" "unprognostic (2.78e-3)" "unprognostic (9.84e-2)" "unprognostic (1.99e-2)" "unprognostic (3.74e-2)" "unprognostic (2.71e-1)" "unprognostic (1.18e-2)" "unprognostic (1.21e-1)" "unprognostic (3.40e-3)" "unprognostic (4.18e-2)" "unprognostic (2.65e-1)" "unprognostic (8.77e-3)" "unprognostic (1.94e-2)" PLD5 FLJ40773 ENSG00000180287 "Phospholipase D family member 5" Q8N7P1 1 242082986-242524697 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "blood vessel: 10.5;brain: 7.0;choroid plexus: 26.1" "Group enriched" "Detected in many" 6 "Choroid plexus epithelial cells: 2655.7;Gonadotrophs: 697.7;Retinal pigment epithelial cells: 1956.7" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 2105.2" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 2.5;Lung Adenocarcinoma (TCGA): 1.6" "Group enriched" "Detected in all" 9 "cerebellum: 34.9;choroid plexus: 117.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 5.9;Neuroblastoma: 4.9" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal cortex cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028389 Approved Mitochondria No No "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 5: Non-specific - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 5 Mitochondria "HPA028389: " "unprognostic (3.87e-1)" "unprognostic (1.54e-2)" "unprognostic (4.01e-2)" "unprognostic (2.48e-1)" PLD6 Zuc ENSG00000179598 "Phospholipase D family member 6" Q8N2A8 17 17200995-17206333 "Metabolic proteins, Predicted membrane proteins" "Differentiation, Lipid degradation, Lipid metabolism, Meiosis, Spermatogenesis" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 21.2" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 26.8;Early primary spermatocytes: 25.4;Late primary spermatocytes: 26.4;Oocytes: 59.9;Undifferentiated spermatogonia: 23.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 5.8;NK-cells: 6.2;T-cells: 11.9" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Heart muscle - Cardiomyocytes, Testis - Spermatocytes" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" HPA049345 Approved NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 67: Testis - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 9 "HPA049345: " "unprognostic (5.77e-2)" "unprognostic (2.66e-3)" "unprognostic (3.06e-1)" "unprognostic (2.59e-2)" "unprognostic (1.70e-1)" "unprognostic (3.08e-2)" "unprognostic (1.49e-1)" "unprognostic (4.03e-2)" "unprognostic (1.97e-1)" "unprognostic (4.11e-1)" "unprognostic (1.02e-1)" "unprognostic (1.30e-1)" "unprognostic (1.87e-1)" "unprognostic (2.09e-1)" "unprognostic (6.32e-2)" "unprognostic (2.74e-1)" "unprognostic (4.46e-1)" "unprognostic (3.88e-2)" "unprognostic (5.44e-2)" "unprognostic (2.44e-1)" "unprognostic (2.78e-1)" "unprognostic (2.42e-3)" "unprognostic (3.28e-1)" "unprognostic (1.06e-1)" "unprognostic (4.95e-1)" "unprognostic (4.68e-2)" "unprognostic (9.81e-2)" "unprognostic (1.91e-1)" "unprognostic (3.74e-1)" "unprognostic (9.22e-2)" "unprognostic (5.83e-2)" PLEC "EBS1, PCN, PLEC1, PLTN" ENSG00000178209 Plectin Q15149 8 143915153-143976734 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Cancer-related genes, Disease variant, Epidermolysis bullosa, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 229.5" "Cell type enhanced" "Detected in many" "Urothelial cells: 231.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003847, HPA025967, HPA029906" Enhanced Supported "Intermediate filaments,Focal adhesion sites,Cytosol" NA NA 3600000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 44: Non-specific - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 69: Urothelial cells - Basic cellular functions" 53 "Intermediate filaments, Cytosol" "Focal adhesion sites" "CAB003847: , HPA025967: , HPA029906: " "unprognostic (3.30e-1)" "unprognostic (4.77e-2)" "unprognostic (2.69e-2)" "potential prognostic unfavorable (3.42e-4)" "unprognostic (2.88e-1)" "unprognostic (4.18e-2)" "unprognostic (2.74e-1)" "unprognostic (1.76e-1)" "unprognostic (6.00e-2)" "unprognostic (2.67e-1)" "unprognostic (1.44e-1)" "unprognostic (2.13e-1)" "unprognostic (8.99e-2)" "unprognostic (7.98e-3)" "unprognostic (1.73e-1)" "potential prognostic unfavorable (3.71e-4)" "unprognostic (3.38e-2)" "unprognostic (6.95e-2)" "unprognostic (1.27e-1)" "unprognostic (1.60e-2)" "unprognostic (9.95e-3)" "potential prognostic unfavorable (5.24e-4)" "unprognostic (2.01e-3)" "unprognostic (9.51e-2)" "unprognostic (4.23e-2)" "potential prognostic favorable (2.00e-4)" "unprognostic (5.29e-2)" "unprognostic (1.20e-1)" "unprognostic (7.92e-2)" "unprognostic (3.67e-2)" "unprognostic (6.64e-2)" PLEK "P47, PLEK1" ENSG00000115956 Pleckstrin P08567 2 68365282-68397453 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "bone marrow: 571.1" "Group enriched" "Detected in many" 5 "Megakaryocyte progenitors: 1905.8;Megakaryocytes: 6979.0;Neutrophils: 5200.3" "Group enriched" "Detected in many" 5 "central nervous system macrophage: 140.2;leukocyte: 105.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 43 "Leukemia: 118.8;lymphoma: 185.1;Myeloma: 58.9" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Minor Salivary Gland - Macrophages, Skeletal muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031838, HPA057341" Enhanced Approved Nucleoli NA NA 300000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 15: Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 55: Lymphoma - Immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 4 Nucleoli "HPA031838: , HPA057341: " "unprognostic (1.54e-2)" "unprognostic (2.64e-2)" "unprognostic (1.03e-1)" "unprognostic (2.73e-1)" "unprognostic (6.95e-2)" "unprognostic (6.48e-2)" "unprognostic (6.17e-2)" "unprognostic (1.04e-1)" "unprognostic (3.65e-2)" "unprognostic (2.65e-1)" "unprognostic (6.33e-2)" "unprognostic (4.21e-1)" "unprognostic (2.68e-1)" "unprognostic (8.43e-2)" "unprognostic (1.35e-1)" "unprognostic (1.18e-3)" "unprognostic (1.87e-2)" "unprognostic (2.60e-1)" "unprognostic (9.27e-2)" "unprognostic (1.17e-1)" "unprognostic (2.23e-1)" "unprognostic (8.42e-2)" "unprognostic (6.25e-3)" "unprognostic (6.59e-2)" "unprognostic (1.17e-2)" "unprognostic (1.27e-1)" "unprognostic (1.21e-1)" "unprognostic (3.21e-1)" "unprognostic (4.07e-2)" "unprognostic (2.78e-1)" "unprognostic (3.91e-1)" PLEK2 ENSG00000100558 "Pleckstrin 2" Q9NYT0 14 67386984-67412167 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 48.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 125.3;Enteric stem cells: 51.8;Enteric transient amplifying cells: 56.1;Enterocytes: 49.2;Epididymal clear cells: 44.9;Epididymal principal cells: 48.3;Esophageal basal cells: 73.7;Gastric progenitor cells: 67.9;Goblet cells: 59.7;Oocytes: 41.4;Paneth cells: 61.9;Suprabasal keratinocytes: 78.9" "Cell type enriched" "Detected in single" 4 "fibroblast: 3.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 6 "memory CD4 T-cell: 2.0;naive CD4 T-cell: 3.1" "Lineage enriched" "Detected in single" 7 "T-cells: 3.1" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal cortex cells, Colon - Colon enterocytes, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other), Spleen - Erythrocytes, Testis - Leydig cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA001208 Enhanced Uncertain Vesicles,Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 77: Intestine - Digestion" "Cluster 15: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 26: Keratinocytes - Keratinization" 3 Vesicles Cytosol "HPA001208: " "unprognostic (1.97e-1)" "unprognostic (7.22e-2)" "unprognostic (2.02e-2)" "unprognostic (3.62e-1)" "unprognostic (2.68e-1)" "unprognostic (2.59e-1)" "unprognostic (2.23e-2)" "unprognostic (5.76e-2)" "unprognostic (2.28e-3)" "unprognostic (3.21e-1)" "unprognostic (2.68e-2)" "unprognostic (1.93e-1)" "unprognostic (1.54e-2)" "unprognostic (1.20e-2)" "unprognostic (1.03e-1)" "potential prognostic unfavorable (4.21e-5)" "unprognostic (4.41e-3)" "unprognostic (5.79e-2)" "unprognostic (2.27e-3)" "unprognostic (1.96e-3)" "unprognostic (2.67e-1)" "potential prognostic unfavorable (2.01e-4)" "unprognostic (2.18e-3)" "unprognostic (1.08e-1)" "unprognostic (1.28e-1)" "unprognostic (4.18e-2)" "unprognostic (7.25e-2)" "unprognostic (2.03e-1)" "unprognostic (3.82e-1)" "unprognostic (7.02e-2)" "unprognostic (3.34e-2)" PLEKHA1 TAPP1 ENSG00000107679 "Pleckstrin homology domain containing A1" Q9HB21 10 122374696-122432354 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 635.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 6 "B-cells: 10.7;NK-cells: 22.0;T-cells: 28.2" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002043, HPA064795" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 53: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 18 Nucleoplasm Cytosol "HPA002043: , HPA064795: " "unprognostic (2.16e-1)" "unprognostic (3.34e-2)" "unprognostic (1.11e-1)" "unprognostic (3.25e-2)" "unprognostic (1.26e-1)" "unprognostic (8.71e-3)" "unprognostic (1.85e-1)" "unprognostic (4.16e-2)" "unprognostic (9.23e-2)" "unprognostic (4.80e-2)" "potential prognostic favorable (8.36e-8)" "unprognostic (1.93e-3)" "unprognostic (9.92e-2)" "unprognostic (3.56e-2)" "unprognostic (2.86e-1)" "unprognostic (2.76e-1)" "unprognostic (2.00e-2)" "unprognostic (5.26e-3)" "unprognostic (4.87e-2)" "unprognostic (1.02e-1)" "potential prognostic unfavorable (9.96e-5)" "unprognostic (7.53e-2)" "unprognostic (2.07e-3)" "unprognostic (5.54e-2)" "unprognostic (9.76e-2)" "unprognostic (2.85e-1)" "unprognostic (2.27e-1)" "unprognostic (2.56e-1)" "unprognostic (9.10e-2)" "unprognostic (6.36e-2)" "unprognostic (1.02e-1)" PLEKHA2 TAPP2 ENSG00000169499 "Pleckstrin homology domain containing A2" 8 38901235-38973912 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 73.5" "Cell type enhanced" "Detected in many" "B-cells: 321.7;Innate lymphoid cells: 274.0;Neutrophil progenitors: 344.6;NK-cells: 265.8;Podocytes: 252.4;Renal collecting duct principal cells: 271.1" "Cell type enhanced" "Detected in all" "leukocyte: 222.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Prostate - Fibroblasts, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004706 Approved Uncertain "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 51: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 15 "Nucleoplasm, Nuclear bodies, Cytosol" "HPA004706: " "unprognostic (2.54e-2)" "unprognostic (1.65e-1)" "unprognostic (3.89e-2)" "unprognostic (3.76e-3)" "unprognostic (1.86e-1)" "unprognostic (6.05e-2)" "unprognostic (1.81e-1)" "unprognostic (4.94e-1)" "unprognostic (1.97e-2)" "potential prognostic unfavorable (4.98e-5)" "validated prognostic favorable (4.32e-7)" "validated prognostic favorable (6.68e-5)" "unprognostic (1.56e-2)" "unprognostic (1.40e-2)" "unprognostic (1.39e-1)" "unprognostic (8.64e-2)" "unprognostic (1.68e-1)" "unprognostic (1.89e-1)" "unprognostic (2.68e-2)" "unprognostic (2.26e-1)" "unprognostic (1.68e-2)" "unprognostic (7.58e-3)" "unprognostic (4.80e-1)" "unprognostic (2.89e-2)" "unprognostic (9.56e-2)" "unprognostic (9.49e-3)" "unprognostic (1.16e-1)" "unprognostic (3.03e-1)" "unprognostic (1.38e-1)" "unprognostic (3.96e-2)" "unprognostic (6.33e-2)" PLEKHA3 FAPP1 ENSG00000116095 "Pleckstrin homology domain containing A3" Q9HB20 2 178480457-178516463 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 196.0;Late spermatids: 739.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034496, HPA034497" Approved Enhanced "Golgi apparatus" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 35: Non-specific - Mixed function" "Cluster 16: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 14 "Golgi apparatus" "HPA034496: , HPA034497: " "unprognostic (6.55e-2)" "unprognostic (3.62e-3)" "unprognostic (1.92e-1)" "unprognostic (2.41e-1)" "unprognostic (2.34e-1)" "unprognostic (2.03e-1)" "unprognostic (6.12e-2)" "unprognostic (3.94e-1)" "unprognostic (1.41e-1)" "unprognostic (2.29e-1)" "potential prognostic favorable (4.90e-7)" "unprognostic (1.67e-3)" "unprognostic (1.50e-3)" "unprognostic (3.24e-3)" "unprognostic (1.35e-2)" "unprognostic (5.77e-2)" "unprognostic (6.06e-2)" "unprognostic (2.53e-1)" "unprognostic (1.50e-1)" "unprognostic (2.70e-1)" "unprognostic (2.25e-2)" "unprognostic (7.73e-2)" "unprognostic (2.22e-1)" "unprognostic (1.52e-1)" "unprognostic (3.89e-1)" "unprognostic (3.74e-3)" "unprognostic (5.24e-2)" "unprognostic (7.67e-2)" "unprognostic (1.05e-1)" "unprognostic (1.81e-1)" "unprognostic (5.57e-2)" PLEKHA4 PEPP1 ENSG00000105559 "Pleckstrin homology domain containing A4" Q9H4M7 19 48837092-48868617 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Epididymal basal cells: 104.3;Epididymal clear cells: 61.2;Leydig cells: 65.9;Ovarian stromal cells: 65.7;Pituitary stem cells: 59.3;Salivary myoepithelial cells: 63.0;Schwann cells: 134.1" "Cell type enhanced" "Detected in many" "ependymal cell: 16.9;fibroblast: 16.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 35.4" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Minor Salivary Gland - Endothelial cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in some" "Region enriched" "Detected in all" 6 "spinal cord: 59.6" "HPA042978, HPA048473" Uncertain Approved "Plasma membrane,Cytokinetic bridge,Centriolar satellite,Cytosol" Yes No "Cluster 74: Non-specific - Signal transduction" "Cluster 39: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 103: Non-specific - Basic cellular processes" 5 "Plasma membrane, Cytosol" "Cytokinetic bridge, Centriolar satellite" "HPA042978: , HPA048473: " "unprognostic (7.09e-2)" "potential prognostic favorable (2.77e-4)" "unprognostic (5.65e-3)" "unprognostic (9.35e-2)" "unprognostic (7.55e-2)" "unprognostic (3.55e-1)" "unprognostic (1.08e-1)" "potential prognostic unfavorable (6.12e-4)" "unprognostic (9.90e-2)" "unprognostic (1.12e-1)" "unprognostic (4.35e-1)" "unprognostic (1.82e-1)" "unprognostic (1.38e-3)" "potential prognostic unfavorable (5.83e-4)" "unprognostic (1.45e-1)" "unprognostic (2.32e-1)" "unprognostic (6.28e-3)" "unprognostic (5.94e-2)" "unprognostic (1.38e-1)" "unprognostic (1.73e-2)" "unprognostic (1.60e-1)" "unprognostic (2.69e-2)" "unprognostic (1.35e-1)" "unprognostic (4.47e-1)" "unprognostic (1.34e-1)" "potential prognostic favorable (1.49e-4)" "unprognostic (3.85e-2)" "unprognostic (1.58e-1)" "unprognostic (4.85e-2)" "unprognostic (8.12e-3)" "unprognostic (7.01e-2)" PLEKHA5 "FLJ10667, KIAA1686, PEPP2" ENSG00000052126 "Pleckstrin homology domain containing A5" Q9HAU0 12 19129669-19376400 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ependymal cells: 2159.6;Melanocytes: 1780.6;Pituicytes/FSCs: 1478.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 10.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 10.9" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035923, HPA035924, HPA041455" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 32 "Nucleoplasm, Cytosol" "HPA035923: , HPA035924: , HPA041455: " "unprognostic (1.20e-1)" "unprognostic (7.75e-2)" "unprognostic (1.72e-1)" "unprognostic (1.97e-1)" "unprognostic (3.70e-1)" "unprognostic (1.55e-1)" "unprognostic (2.44e-1)" "unprognostic (1.29e-2)" "unprognostic (3.95e-1)" "unprognostic (1.25e-1)" "unprognostic (1.20e-2)" "unprognostic (5.21e-3)" "unprognostic (1.97e-1)" "unprognostic (1.50e-1)" "unprognostic (2.77e-1)" "unprognostic (1.41e-1)" "unprognostic (2.58e-3)" "unprognostic (6.31e-3)" "unprognostic (5.77e-2)" "unprognostic (9.23e-2)" "unprognostic (2.75e-1)" "unprognostic (2.99e-3)" "unprognostic (1.81e-2)" "unprognostic (8.42e-2)" "unprognostic (4.40e-2)" "unprognostic (4.55e-2)" "unprognostic (1.11e-1)" "unprognostic (2.43e-1)" "unprognostic (2.01e-1)" "unprognostic (1.90e-1)" "unprognostic (3.60e-1)" PLEKHA6 "KIAA0969, PEPP3" ENSG00000143850 "Pleckstrin homology domain containing A6" Q9Y2H5 1 204218853-204377665 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 280.9;Proximal tubule cells: 565.1;Retinal amacrine cells: 272.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028152, HPA028157, HPA054311" Enhanced Approved "Vesicles,Cell Junctions" NA NA "Cluster 64: Non-specific - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 88: Proximal tubular cells - Transmembrane transport" 3 "Cell Junctions" Vesicles "HPA028152: , HPA028157: , HPA054311: " "unprognostic (1.10e-1)" "unprognostic (7.70e-2)" "unprognostic (1.46e-1)" "unprognostic (2.50e-2)" "potential prognostic favorable (5.29e-4)" "unprognostic (2.02e-1)" "unprognostic (5.47e-2)" "unprognostic (1.27e-1)" "unprognostic (2.77e-1)" "unprognostic (1.13e-1)" "potential prognostic favorable (7.70e-6)" "unprognostic (1.98e-1)" "unprognostic (1.37e-1)" "unprognostic (1.89e-2)" "unprognostic (1.79e-1)" "unprognostic (5.43e-3)" "unprognostic (4.17e-3)" "potential prognostic unfavorable (2.50e-5)" "unprognostic (5.33e-2)" "unprognostic (2.31e-1)" "unprognostic (1.41e-1)" "unprognostic (1.91e-1)" "unprognostic (2.81e-1)" "unprognostic (1.64e-1)" "unprognostic (7.77e-2)" "unprognostic (4.43e-2)" "unprognostic (1.09e-1)" "unprognostic (1.93e-2)" "unprognostic (5.18e-2)" "unprognostic (1.74e-1)" "unprognostic (3.09e-2)" PLEKHA7 DKFZp686M22243 ENSG00000166689 "Pleckstrin homology domain containing A7" Q6IQ23 11 16777297-17014415 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Choroid plexus epithelial cells: 665.4;Cone photoreceptor cells: 728.7;Ependymal cells: 619.0;Esophageal apical cells: 643.0;Proximal tubule cells: 879.2;Retinal pigment epithelial cells: 656.5" "Group enriched" "Detected in all" 4 "astrocyte: 194.4;Bergmann glia: 195.6;choroid plexus epithelial cell: 484.7;ependymal cell: 620.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "eosinophil: 3.7;MAIT T-cell: 1.9" "Group enriched" "Detected in many" 6 "granulocytes: 3.7;T-cells: 1.9" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Prostate - Urothelial cells, Skeletal muscle - Endothelial cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038610, HPA066103" Approved Enhanced "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 88: Proximal tubular cells - Transmembrane transport" 25 "Nucleoplasm, Cell Junctions" Cytosol "HPA038610: , HPA066103: " "unprognostic (5.02e-3)" "unprognostic (2.89e-1)" "unprognostic (5.12e-2)" "unprognostic (1.54e-2)" "unprognostic (3.17e-1)" "unprognostic (2.82e-1)" "unprognostic (3.90e-2)" "unprognostic (8.23e-2)" "unprognostic (6.32e-3)" "unprognostic (8.90e-2)" "validated prognostic favorable (6.02e-9)" "validated prognostic favorable (2.58e-4)" "potential prognostic favorable (5.92e-7)" "unprognostic (1.10e-2)" "unprognostic (4.58e-2)" "unprognostic (1.33e-1)" "unprognostic (3.61e-2)" "unprognostic (8.82e-2)" "unprognostic (2.42e-1)" "unprognostic (2.31e-1)" "unprognostic (2.18e-1)" "unprognostic (2.81e-3)" "unprognostic (4.67e-3)" "unprognostic (2.39e-2)" "unprognostic (3.96e-3)" "unprognostic (2.84e-1)" "unprognostic (2.36e-1)" "unprognostic (1.14e-1)" "unprognostic (1.66e-2)" "unprognostic (3.33e-1)" "unprognostic (3.69e-1)" PLEKHA8 "FAPP2, MGC3358" ENSG00000106086 "Pleckstrin homology domain containing A8" Q96JA3 7 30027404-30130483 "Predicted intracellular proteins" "Lipid transport, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Renal collecting duct intercalated cells: 111.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072314 Uncertain "Nucleoplasm,Golgi apparatus" NA NA "Cluster 42: Retina - Visual perception" "Cluster 31: Non-specific - Transcription" "Cluster 67: Non-specific - Unknown function" "Cluster 51: Secretory epithelial cells - Mixed function" 1 "Golgi apparatus" Nucleoplasm "HPA072314: " "unprognostic (2.85e-1)" "unprognostic (1.03e-3)" "unprognostic (1.34e-1)" "unprognostic (1.41e-2)" "unprognostic (3.98e-1)" "unprognostic (3.26e-1)" "unprognostic (4.20e-1)" "unprognostic (1.66e-1)" "unprognostic (9.23e-2)" "unprognostic (3.04e-1)" "unprognostic (1.84e-3)" "unprognostic (1.78e-2)" "unprognostic (3.48e-2)" "potential prognostic unfavorable (4.48e-4)" "unprognostic (2.53e-1)" "unprognostic (1.06e-1)" "unprognostic (3.91e-2)" "unprognostic (2.37e-1)" "unprognostic (1.22e-2)" "unprognostic (5.19e-2)" "unprognostic (2.02e-2)" "unprognostic (2.13e-2)" "potential prognostic unfavorable (2.34e-4)" "unprognostic (1.53e-1)" "unprognostic (3.74e-2)" "unprognostic (6.46e-2)" "unprognostic (8.39e-2)" "unprognostic (8.12e-2)" "unprognostic (2.53e-1)" "unprognostic (1.67e-3)" "unprognostic (2.24e-1)" PLEKHB1 "KPL1, PHR1, PHRET1" ENSG00000021300 "Pleckstrin homology domain containing B1" Q9UF11 11 73646178-73662819 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 2714.0;retina: 703.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 505.1;Early spermatids: 183.5;Late spermatids: 322.0;Müller glia: 320.4;Oligodendrocytes: 136.7;Retinal pigment epithelial cells: 648.0;Rod photoreceptor cells: 397.3;Tuft cells: 115.3" "Cell type enhanced" "Detected in many" "astrocyte: 75.1;oligodendrocyte: 179.2" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 232.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 84.0" "Lineage enriched" "Detected in many" 5 "T-cells: 84.0" "Cancer enhanced" "Detected in many" "prostate cancer: 59.4" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Minor Salivary Gland - Minor salivary glandular cells, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" 5 "unprognostic (6.86e-3)" "unprognostic (1.27e-1)" "unprognostic (2.07e-1)" "unprognostic (1.07e-1)" "unprognostic (1.84e-1)" "unprognostic (6.08e-2)" "unprognostic (3.48e-1)" "unprognostic (1.66e-1)" "unprognostic (4.58e-1)" "unprognostic (2.13e-2)" "unprognostic (1.12e-1)" "unprognostic (1.50e-1)" "potential prognostic favorable (4.05e-4)" "unprognostic (2.68e-2)" "unprognostic (1.50e-3)" "potential prognostic favorable (8.52e-7)" "unprognostic (2.24e-1)" "unprognostic (2.12e-3)" "unprognostic (1.98e-1)" "unprognostic (5.52e-2)" "unprognostic (2.92e-2)" "unprognostic (1.05e-3)" "unprognostic (1.89e-1)" "unprognostic (2.19e-1)" "unprognostic (9.20e-2)" "unprognostic (1.11e-2)" "unprognostic (5.75e-2)" "unprognostic (1.62e-1)" "unprognostic (6.81e-2)" "unprognostic (3.16e-1)" "unprognostic (1.06e-1)" PLEKHB2 "EVT2, FLJ20783" ENSG00000115762 "Pleckstrin homology domain containing B2" Q96CS7 2 131104847-131353709 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial glandular cells: 331.0;Endometrial luminal cells: 303.9;Parietal cells: 346.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adrenal gland - Adrenal cortex cells, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075014 Approved NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 45: Non-specific - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 51: Secretory epithelial cells - Mixed function" 37 "HPA075014: " "unprognostic (5.41e-3)" "potential prognostic unfavorable (6.00e-4)" "unprognostic (2.35e-1)" "unprognostic (4.03e-2)" "unprognostic (1.81e-1)" "unprognostic (3.50e-1)" "unprognostic (1.28e-1)" "unprognostic (2.41e-3)" "unprognostic (6.05e-2)" "unprognostic (3.97e-2)" "potential prognostic favorable (1.01e-6)" "unprognostic (6.70e-2)" "unprognostic (1.58e-2)" "unprognostic (1.60e-3)" "unprognostic (3.94e-2)" "unprognostic (4.59e-2)" "unprognostic (1.24e-1)" "unprognostic (4.91e-2)" "unprognostic (1.42e-1)" "unprognostic (6.87e-2)" "unprognostic (6.11e-2)" "unprognostic (2.80e-2)" "unprognostic (3.03e-1)" "unprognostic (1.61e-1)" "unprognostic (1.17e-1)" "unprognostic (7.50e-2)" "unprognostic (1.25e-1)" "unprognostic (9.48e-2)" "unprognostic (3.19e-1)" "unprognostic (2.22e-2)" "unprognostic (6.37e-2)" PLEKHD1 UPF0639 ENSG00000175985 "Pleckstrin homology and coiled-coil domain containing D1" A6NEE1 14 69484692-69531551 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.5;parathyroid gland: 5.6;retina: 8.1" "Cell type enriched" "Detected in many" 4 "Retinal horizontal cells: 364.6" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 113.1" "Cancer enriched" "Detected in some" 4 "Kidney Chromophobe (TCGA): 7.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 15 "plasmacytoid DC: 3.7" "Lineage enriched" "Detected in single" 15 "dendritic cells: 3.7" "Cancer enhanced" "Detected in some" "prostate cancer: 2.5" "Breast - Breast glandular cells, Pituitary gland - Corticotropes, Skin - Eccrine sweat gland cells, Testis - Early spermatids, Testis - Late spermatids" "Region enhanced" "Detected in many" "cerebellum: 30.0" "Low region specificity" "Detected in all" HPA051875 Uncertain NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 109: Neurons - Neuronal signaling" "HPA051875: " "unprognostic (9.47e-2)" "unprognostic (2.85e-2)" "unprognostic (3.87e-2)" "unprognostic (3.96e-3)" "unprognostic (6.13e-2)" "unprognostic (7.63e-2)" "unprognostic (3.06e-2)" PLEKHF1 "APPD, MGC4090, PHAFIN1, ZFYVE15" ENSG00000166289 "Pleckstrin homology and FYVE domain containing 1" Q96S99 19 29665459-29675477 "Predicted intracellular proteins, Transporters" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 87.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 78.9;Decidual stromal cells: 49.9;Esophageal apical cells: 160.9;Leydig cells: 71.4;Migrating cytotrophoblasts: 49.2;NK-cells: 51.5;Peritubular myoid cells: 74.3;Syncytiotrophoblasts: 48.4" "Cell type enhanced" "Detected in many" "endothelial cell: 20.2;leukocyte: 36.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 13 "NK-cells: 82.6;T-cells: 184.2" "Low cancer specificity" "Detected in all" "Spleen - T-cells, Stomach - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA025925 Uncertain NA NA "Cluster 1: T-cells - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 4 "HPA025925: " "unprognostic (5.12e-2)" "unprognostic (6.42e-2)" "unprognostic (3.37e-2)" "unprognostic (1.24e-1)" "unprognostic (1.77e-3)" "unprognostic (1.40e-1)" "unprognostic (6.48e-3)" "unprognostic (5.42e-3)" "unprognostic (1.28e-2)" "unprognostic (2.69e-1)" "potential prognostic unfavorable (2.70e-5)" "unprognostic (1.00e-1)" "unprognostic (9.99e-2)" "unprognostic (2.24e-2)" "unprognostic (1.12e-3)" "potential prognostic favorable (1.54e-5)" "unprognostic (9.63e-2)" "unprognostic (7.22e-3)" "unprognostic (9.66e-2)" "unprognostic (3.60e-3)" "unprognostic (2.77e-2)" "unprognostic (1.26e-1)" "unprognostic (3.21e-2)" "unprognostic (1.95e-1)" "unprognostic (1.54e-1)" "unprognostic (8.02e-2)" "unprognostic (5.60e-2)" "unprognostic (8.04e-2)" "unprognostic (3.58e-1)" "unprognostic (1.28e-3)" "unprognostic (2.24e-1)" PLEKHF2 "FLJ13187, PHAFIN2, ZFYVE18" ENSG00000175895 "Pleckstrin homology and FYVE domain containing 2" Q9H8W4 8 95115642-95156698 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 96.7;lymphoid tissue: 67.2" "Cell type enhanced" "Detected in many" "Neutrophils: 157.0" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 49.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024829 Uncertain NA NA "Cluster 32: Basophils - Transcription" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 121 "HPA024829: " "unprognostic (1.47e-1)" "unprognostic (8.61e-2)" "unprognostic (5.33e-3)" "unprognostic (1.27e-1)" "unprognostic (1.61e-1)" "unprognostic (6.89e-3)" "unprognostic (2.09e-2)" "unprognostic (6.61e-2)" "unprognostic (1.31e-1)" "unprognostic (1.23e-3)" "validated prognostic favorable (1.18e-10)" "validated prognostic favorable (9.89e-5)" "potential prognostic favorable (1.39e-4)" "unprognostic (5.77e-2)" "unprognostic (5.06e-2)" "unprognostic (3.13e-1)" "unprognostic (7.01e-2)" "unprognostic (1.89e-1)" "unprognostic (3.86e-1)" "unprognostic (7.31e-2)" "unprognostic (1.71e-2)" "unprognostic (5.98e-2)" "potential prognostic unfavorable (2.31e-4)" "unprognostic (2.00e-2)" "unprognostic (6.78e-2)" "unprognostic (8.91e-2)" "unprognostic (3.62e-1)" "unprognostic (7.04e-2)" "unprognostic (3.54e-1)" "unprognostic (9.01e-2)" "unprognostic (8.45e-2)" PLEKHG1 "ARHGEF41, KIAA1209" ENSG00000120278 "Pleckstrin homology and RhoGEF domain containing G1" Q9ULL1 6 150599883-150843665 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 27.0" "Cell type enhanced" "Detected in many" "B-cells: 503.6;Lymphatic endothelial cells: 541.3;Pituicytes/FSCs: 362.2;Podocytes: 302.0;Sertoli cells: 508.3;Vascular endothelial cells: 740.3" "Cell type enhanced" "Detected in all" "endothelial cell: 640.9;fibroblast: 371.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 30 "memory B-cell: 22.9;naive B-cell: 21.7" "Lineage enriched" "Detected in single" 31 "B-cells: 22.9" "Low cancer specificity" "Detected in many" "Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Pituitary gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Spleen - Endothelial cells, Stomach - Endothelial cells, Testis - Sertoli cells" "Region enhanced" "Detected in all" "thalamus: 51.3" "Low region specificity" "Detected in all" "HPA027128, HPA027319, HPA028270" Approved Enhanced Nucleoplasm Yes No "Cluster 14: Non-specific - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 45: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 3 Nucleoplasm "HPA027128: , HPA027319: , HPA028270: " "unprognostic (9.12e-3)" "unprognostic (4.12e-2)" "unprognostic (8.13e-2)" "unprognostic (1.84e-1)" "unprognostic (8.34e-2)" "unprognostic (2.54e-1)" "unprognostic (1.05e-1)" "potential prognostic unfavorable (1.51e-4)" "unprognostic (3.95e-3)" "unprognostic (1.90e-1)" "validated prognostic favorable (7.96e-6)" "validated prognostic favorable (1.67e-5)" "unprognostic (8.30e-3)" "unprognostic (2.10e-1)" "unprognostic (1.12e-2)" "unprognostic (7.76e-2)" "unprognostic (7.21e-3)" "unprognostic (1.17e-1)" "unprognostic (2.48e-1)" "unprognostic (7.07e-2)" "unprognostic (3.38e-1)" "unprognostic (2.83e-2)" "unprognostic (1.70e-1)" "unprognostic (1.62e-1)" "unprognostic (4.01e-2)" "unprognostic (1.64e-3)" "unprognostic (8.45e-2)" "unprognostic (2.49e-1)" "unprognostic (9.37e-2)" "unprognostic (6.44e-2)" "unprognostic (6.07e-2)" PLEKHG2 "ARHGEF42, CLG, FLJ00018" ENSG00000090924 "Pleckstrin homology and RhoGEF domain containing G2" Q9H7P9 19 39412669-39428415 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Disease variant, Intellectual disability, Leukodystrophy, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 157.5;Breast myoepithelial cells: 137.8;Medullary thymic epithelial cells: 182.4;monocytes: 106.4;Neutrophils: 128.5;pDCs: 179.7;Salivary acinar cells: 168.0;Salivary myoepithelial cells: 191.6;Thymic myoid cells: 106.1" "Group enriched" "Detected in many" 4 "endothelial cell: 30.1;fibroblast: 28.8;pericyte: 93.6;vascular associated smooth muscle cell: 62.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Pituitary gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017973, HPA048054" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 12: Non-specific - Vasculature" "Cluster 4: Non-specific - Transcription" "Cluster 20: Non-specific - Transcription regulation" 7 Nucleoplasm Cytosol "HPA017973: , HPA048054: " "unprognostic (1.02e-2)" "unprognostic (1.64e-1)" "unprognostic (9.73e-2)" "unprognostic (6.09e-2)" "unprognostic (3.93e-3)" "unprognostic (1.67e-1)" "unprognostic (2.64e-1)" "unprognostic (1.22e-1)" "unprognostic (2.46e-3)" "unprognostic (5.19e-2)" "unprognostic (5.03e-2)" "unprognostic (1.42e-1)" "unprognostic (7.05e-2)" "unprognostic (1.16e-2)" "unprognostic (1.03e-1)" "unprognostic (2.75e-2)" "unprognostic (1.25e-2)" "unprognostic (2.07e-1)" "unprognostic (1.51e-1)" "unprognostic (2.81e-2)" "unprognostic (3.71e-1)" "unprognostic (2.37e-1)" "potential prognostic unfavorable (2.68e-4)" "unprognostic (2.93e-1)" "unprognostic (2.21e-1)" "unprognostic (1.28e-1)" "unprognostic (1.92e-1)" "unprognostic (1.71e-1)" "unprognostic (9.37e-2)" "unprognostic (3.31e-2)" "unprognostic (9.45e-2)" PLEKHG3 "ARHGEF43, KIAA0599" ENSG00000126822 "Pleckstrin homology and RhoGEF domain containing G3" A1L390 14 64704102-64750249 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Loop of henle epithelial cells: 86.1;Oligodendrocytes: 142.7;Renal collecting duct principal cells: 97.0" "Cell type enhanced" "Detected in many" "oligodendrocyte: 154.3;pericyte: 98.4;vascular associated smooth muscle cell: 100.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "granulocytes: 23.5;NK-cells: 9.0;T-cells: 15.4" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Fibroblasts, Heart muscle - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063455, HPA073702, HPA074734" Enhanced Uncertain "Plasma membrane,Cytosol" NA No "Cluster 21: Neutrophils - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 13 "Plasma membrane" Cytosol "HPA063455: , HPA073702: , HPA074734: " "unprognostic (1.00e-1)" "unprognostic (1.54e-1)" "unprognostic (4.05e-1)" "unprognostic (2.22e-2)" "unprognostic (3.11e-2)" "unprognostic (8.77e-2)" "unprognostic (2.19e-1)" "unprognostic (1.49e-2)" "unprognostic (1.13e-1)" "unprognostic (3.00e-1)" "validated prognostic favorable (2.22e-6)" "validated prognostic favorable (1.69e-4)" "unprognostic (5.60e-3)" "unprognostic (1.65e-2)" "unprognostic (2.41e-1)" "unprognostic (1.67e-2)" "unprognostic (7.20e-2)" "unprognostic (1.81e-1)" "unprognostic (3.62e-1)" "unprognostic (9.75e-3)" "unprognostic (1.81e-1)" "unprognostic (2.58e-1)" "unprognostic (2.15e-2)" "unprognostic (4.04e-2)" "unprognostic (3.27e-2)" "unprognostic (1.38e-2)" "unprognostic (2.26e-1)" "unprognostic (1.28e-1)" "unprognostic (1.49e-1)" "unprognostic (7.65e-2)" "unprognostic (5.74e-2)" PLEKHG4 "ARHGEF44, DKFZP434I216, SCA4" ENSG00000196155 "Pleckstrin homology and RhoGEF domain containing G4" Q58EX7 16 67277510-67289499 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 40.1" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 25.1;Early primary spermatocytes: 40.2;Epicardial cells: 11.4;Fibro-adipogenic progenitors: 12.9;Retinal pigment epithelial cells: 17.1;Tuft cells: 11.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Testis - Spermatocytes" "Region enhanced" "Detected in some" "cerebellum: 3.3" "Not detected" "Not detected" HPA055696 Approved "Cell Junctions" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 75: Ovary - Mixed function" "Cluster 30: White matter - Myelination" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 3: Early primary spermatocytes - Early meiosis" 66 "Cell Junctions" "HPA055696: " "unprognostic (2.02e-1)" "unprognostic (2.92e-1)" "unprognostic (4.88e-2)" "unprognostic (2.29e-1)" "unprognostic (1.97e-1)" "unprognostic (6.22e-3)" "unprognostic (2.34e-1)" "unprognostic (1.05e-2)" "unprognostic (6.99e-2)" "potential prognostic unfavorable (4.52e-6)" "unprognostic (4.20e-3)" "unprognostic (1.06e-1)" "unprognostic (1.00e-1)" "unprognostic (6.12e-2)" "unprognostic (1.91e-2)" "unprognostic (1.06e-1)" "potential prognostic favorable (9.59e-4)" "unprognostic (2.94e-2)" "unprognostic (2.89e-1)" "unprognostic (2.95e-2)" "unprognostic (5.22e-2)" "unprognostic (1.79e-1)" "unprognostic (4.96e-2)" "unprognostic (1.56e-1)" "unprognostic (1.12e-1)" "unprognostic (2.64e-1)" "unprognostic (3.55e-1)" "unprognostic (9.93e-3)" "unprognostic (2.37e-1)" PLEKHG4B KIAA1909 ENSG00000153404 "Pleckstrin homology and RhoGEF domain containing G4B" Q96PX9 5 92168-189972 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 7.9" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 235.2;Endometrial luminal cells: 37.5;Ependymal cells: 121.6;Gonadotrophs: 108.2;Pituitary stem cells: 67.7;Renal collecting duct principal cells: 57.5;Somatotrophs: 42.6" "Group enriched" "Detected in many" 4 "choroid plexus epithelial cell: 136.8;ependymal cell: 103.6" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "choroid plexus: 20.8" "Immune cell enriched" "Detected in single" 20 "plasmacytoid DC: 1.9" "Lineage enriched" "Detected in single" 20 "dendritic cells: 1.9" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Lung - Respiratory ciliated cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "HPA036274, HPA058157" Uncertain Approved Nucleoplasm NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 6: Leukemia - Signal transduction" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 6 Nucleoplasm "HPA036274: , HPA058157: " "unprognostic (1.55e-1)" "unprognostic (1.11e-2)" "unprognostic (2.61e-1)" "potential prognostic unfavorable (3.33e-4)" "unprognostic (3.05e-1)" "unprognostic (1.84e-1)" "unprognostic (1.84e-3)" "unprognostic (9.58e-2)" "unprognostic (6.03e-3)" "unprognostic (2.98e-2)" "unprognostic (1.71e-1)" "unprognostic (6.61e-2)" "unprognostic (1.82e-2)" "unprognostic (1.16e-1)" "unprognostic (9.33e-2)" "unprognostic (5.35e-1)" "potential prognostic unfavorable (6.36e-4)" "unprognostic (8.26e-2)" PLEKHG5 "GEF720, KIAA0720, Syx, Tech" ENSG00000171680 "Pleckstrin homology and RhoGEF domain containing G5" O94827 1 6467122-6520074 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 139.7;skin 1: 96.9" "Cell type enhanced" "Detected in many" "Adipocytes: 37.0;Corticotrophs: 45.4;Esophageal apical cells: 44.9;Esophageal basal cells: 35.0;Esophageal suprabasal cells: 59.4;Müller glia: 36.2;Ocular epithelial cells: 44.7;Suprabasal keratinocytes: 43.0;Tuft cells: 34.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Pituitary gland - Corticotropes, Skeletal muscle - Fibroblasts, Skin - Keratinocyte (other), Testis - Peritubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049570 Uncertain Approved Nucleoplasm NA NA "Cluster 2: Non-specific - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 3 Nucleoplasm "HPA049570: " "unprognostic (1.03e-1)" "unprognostic (2.28e-1)" "unprognostic (1.12e-1)" "unprognostic (4.62e-2)" "unprognostic (1.28e-1)" "unprognostic (5.87e-2)" "unprognostic (1.69e-2)" "unprognostic (1.28e-1)" "unprognostic (4.20e-1)" "unprognostic (2.09e-1)" "unprognostic (5.21e-2)" "unprognostic (2.07e-2)" "unprognostic (1.11e-2)" "unprognostic (9.64e-3)" "unprognostic (2.10e-3)" "unprognostic (1.34e-1)" "unprognostic (1.07e-1)" "unprognostic (1.60e-1)" "unprognostic (7.02e-2)" "unprognostic (5.78e-2)" "unprognostic (2.13e-2)" "unprognostic (2.21e-1)" "unprognostic (1.63e-3)" "unprognostic (1.25e-1)" "unprognostic (4.15e-2)" "unprognostic (6.78e-2)" "unprognostic (2.58e-2)" "unprognostic (2.95e-1)" "unprognostic (7.55e-2)" "unprognostic (1.10e-1)" "unprognostic (2.45e-1)" PLEKHG6 "FLJ10665, MYOGEF" ENSG00000008323 "Pleckstrin homology and RhoGEF domain containing G6" Q3KR16 12 6310436-6328506 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 24.5;intestine: 37.7" "Cell type enhanced" "Detected in many" "Colonocytes: 152.3;Enterocytes: 170.0;Epicardial cells: 129.6;Esophageal apical cells: 124.8;Extravillous trophoblasts: 122.4;Paneth cells: 69.6;Tuft cells: 92.2;Urothelial cells: 77.4" "Cell type enhanced" "Detected in single" "endothelial cell: 1.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Colon - Colon enterocytes, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA041459, HPA058230" Uncertain Supported "Cell Junctions,Centrosome" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 17: Intestine - Digestion" "Cluster 19: Astrocytes - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 1 "Cell Junctions" Centrosome "HPA041459: , HPA058230: " "unprognostic (1.08e-1)" "unprognostic (2.03e-2)" "unprognostic (3.26e-2)" "unprognostic (7.56e-2)" "unprognostic (1.84e-1)" "unprognostic (9.55e-2)" "unprognostic (1.18e-1)" "unprognostic (2.31e-1)" "unprognostic (9.40e-2)" "unprognostic (3.68e-1)" "unprognostic (1.31e-2)" "unprognostic (1.16e-1)" "potential prognostic unfavorable (4.02e-5)" "unprognostic (8.92e-3)" "unprognostic (8.58e-2)" "unprognostic (4.12e-1)" "unprognostic (1.11e-1)" "unprognostic (3.17e-1)" "unprognostic (1.60e-1)" "unprognostic (5.88e-2)" "unprognostic (5.15e-3)" "unprognostic (5.09e-2)" "unprognostic (4.82e-2)" "unprognostic (2.43e-2)" "unprognostic (5.69e-2)" "unprognostic (1.83e-1)" "unprognostic (5.23e-1)" "unprognostic (2.13e-2)" "unprognostic (1.66e-1)" PLEKHG7 "C12orf74, FLJ46688" ENSG00000187510 "Pleckstrin homology and RhoGEF domain containing G7" Q6ZR37 12 92702843-92772455 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 1.8;fallopian tube: 2.5" "Cell type enhanced" "Detected in many" "B-cells: 81.4;Conjunctival goblet cells: 64.1;Endometrial ciliated cells: 96.1;Epididymal efferent duct ciliated cells: 44.5;Fallopian tube ciliated cells: 85.2;Respiratory basal cells: 38.1;Respiratory ciliated cells: 290.5;Respiratory deuterosomal cells: 71.5;Respiratory secretory cells: 76.7;Tuft cells: 196.0" "Cell type enhanced" "Detected in some" "ependymal cell: 1.8;leukocyte: 2.4" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "memory B-cell: 1.8;naive B-cell: 1.6" "Lineage enriched" "Detected in single" 19 "B-cells: 1.8" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Spleen - B-cells (Spleen)" "HPA047623, HPA060632" Uncertain Uncertain Centrosome NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 22: Epididymis - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 18 Centrosome "HPA047623: , HPA060632: " "potential prognostic favorable (2.17e-4)" "unprognostic (1.81e-1)" "unprognostic (7.37e-2)" "unprognostic (3.11e-1)" "unprognostic (2.14e-1)" "unprognostic (2.40e-1)" "unprognostic (2.90e-1)" "unprognostic (1.37e-3)" PLEKHH1 KIAA1200 ENSG00000054690 "Pleckstrin homology, MyTH4 and FERM domain containing H1" Q9ULM0 14 67533290-67589612 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 42.2;thyroid gland: 35.4" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 109.7;Oligodendrocytes: 854.7;Pituitary stem cells: 169.4;Retinal pigment epithelial cells: 238.7;Salivary acinar cells: 110.4" "Group enriched" "Detected in all" 9 "committed oligodendrocyte precursor: 354.5;oligodendrocyte: 1170.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 16.0" "Heart muscle - Cardiomyocytes, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047707, HPA051964" Uncertain Approved Centrosome NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 60: Prostate cancer - Unknown function" "Cluster 80: Oligodendrocytes - Myelination" 2 Centrosome "HPA047707: , HPA051964: " "unprognostic (5.44e-2)" "unprognostic (3.70e-2)" "unprognostic (3.09e-1)" "unprognostic (1.31e-1)" "unprognostic (1.74e-1)" "unprognostic (1.47e-2)" "unprognostic (2.22e-1)" "unprognostic (2.12e-2)" "unprognostic (1.75e-2)" "unprognostic (1.40e-1)" "potential prognostic favorable (4.77e-8)" "unprognostic (1.67e-3)" "potential prognostic favorable (4.55e-4)" "unprognostic (1.16e-3)" "unprognostic (5.50e-2)" "unprognostic (1.97e-1)" "unprognostic (1.63e-2)" "unprognostic (8.09e-2)" "unprognostic (1.62e-1)" "unprognostic (5.89e-2)" "unprognostic (5.28e-2)" "unprognostic (1.47e-1)" "unprognostic (9.88e-3)" "unprognostic (5.18e-3)" "unprognostic (1.85e-1)" "unprognostic (9.46e-2)" "unprognostic (1.94e-1)" "unprognostic (2.99e-2)" "unprognostic (5.25e-2)" PLEKHH2 "KIAA2028, PLEKHH1L" ENSG00000152527 "Pleckstrin homology, MyTH4 and FERM domain containing H2" Q8IVE3 2 43637260-43767987 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bergmann glia: 529.3;Decidual stromal cells: 299.1;Distal convoluted tubule cells: 176.6;Endometrial stromal cells: 292.8;Fibro-adipogenic progenitors: 274.5;Fibroblasts: 171.0;Loop of henle epithelial cells: 204.9;Mesothelial cells: 166.3;Oligodendrocyte progenitor cells: 316.1;Podocytes: 219.9" "Cell type enhanced" "Detected in many" "Bergmann glia: 524.0;oligodendrocyte precursor cell: 398.1" "Cancer enriched" "Detected in many" 6 "Kidney Renal Papillary Cell Carcinoma (TCGA): 26.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatic stellate cells, Lung - Fibroblasts_1, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077225 Approved "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 15: Kidney cancer - Membrane components" "Cluster 108: Fibroblasts - ECM organization" 7 "Plasma membrane, Cytosol" "Nucleoplasm, Nuclear bodies" "HPA077225: " "unprognostic (1.31e-1)" "unprognostic (1.35e-1)" "unprognostic (3.41e-2)" "unprognostic (2.73e-1)" "unprognostic (6.86e-2)" "unprognostic (4.12e-1)" "unprognostic (5.71e-2)" "unprognostic (1.16e-1)" "validated prognostic favorable (2.54e-4)" "validated prognostic favorable (1.31e-4)" "unprognostic (8.09e-3)" "unprognostic (1.21e-2)" "unprognostic (3.09e-3)" "unprognostic (3.37e-1)" "unprognostic (9.04e-2)" "unprognostic (2.00e-1)" "unprognostic (9.17e-2)" "unprognostic (6.24e-2)" "unprognostic (3.71e-1)" "unprognostic (7.32e-2)" "unprognostic (4.02e-2)" "unprognostic (3.66e-2)" "unprognostic (7.32e-2)" "unprognostic (6.13e-3)" "unprognostic (2.82e-1)" "unprognostic (1.56e-3)" "unprognostic (1.87e-1)" PLEKHH3 FLJ21019 ENSG00000068137 "Pleckstrin homology, MyTH4 and FERM domain containing H3" Q7Z736 17 42667914-42676994 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 39.0" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 64.1;Prostatic hillock cells: 95.2" "Cell type enhanced" "Detected in many" "pericyte: 63.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Minor Salivary Gland - Minor salivary gland basal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046234 Uncertain Approved "Golgi apparatus" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 44: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 110: Mural cells - ECM organization" 1 "Golgi apparatus" "HPA046234: " "unprognostic (2.77e-2)" "unprognostic (2.25e-1)" "unprognostic (5.30e-3)" "unprognostic (9.03e-2)" "unprognostic (3.24e-1)" "unprognostic (1.19e-1)" "unprognostic (1.77e-1)" "unprognostic (1.37e-2)" "unprognostic (7.44e-3)" "unprognostic (1.52e-1)" "potential prognostic favorable (2.53e-6)" "unprognostic (7.56e-3)" "unprognostic (1.78e-1)" "unprognostic (9.25e-3)" "unprognostic (1.17e-1)" "unprognostic (9.50e-2)" "unprognostic (1.92e-1)" "unprognostic (6.78e-2)" "unprognostic (5.86e-2)" "unprognostic (6.80e-3)" "unprognostic (4.96e-1)" "unprognostic (1.99e-1)" "unprognostic (1.91e-1)" "unprognostic (1.83e-1)" "unprognostic (1.44e-1)" "unprognostic (9.37e-3)" "unprognostic (1.60e-1)" "unprognostic (1.81e-1)" "unprognostic (1.47e-1)" "unprognostic (1.75e-2)" "unprognostic (6.51e-2)" PLEKHJ1 FLJ10297 ENSG00000104886 "Pleckstrin homology domain containing J1" Q9NW61 19 2230084-2237704 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 305.2;Enteric transient amplifying cells: 246.6;Enterocytes: 319.0;Paneth cells: 212.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048989 Approved Approved Mitochondria No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 24: Non-specific - Transcription" "Cluster 18: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 12 Mitochondria "HPA048989: " "unprognostic (1.30e-1)" "unprognostic (9.77e-2)" "unprognostic (1.46e-1)" "unprognostic (3.38e-2)" "unprognostic (2.06e-1)" "unprognostic (1.18e-1)" "unprognostic (3.34e-1)" "unprognostic (7.79e-2)" "unprognostic (8.52e-2)" "unprognostic (3.02e-1)" "unprognostic (4.10e-3)" "unprognostic (1.22e-1)" "unprognostic (2.50e-2)" "unprognostic (1.56e-3)" "potential prognostic unfavorable (1.30e-4)" "unprognostic (2.21e-2)" "unprognostic (5.94e-2)" "unprognostic (1.47e-2)" "unprognostic (4.40e-1)" "unprognostic (2.66e-1)" "unprognostic (1.64e-1)" "unprognostic (5.67e-2)" "unprognostic (4.59e-2)" "unprognostic (8.02e-3)" "unprognostic (1.41e-1)" "unprognostic (5.68e-2)" "unprognostic (3.28e-1)" "unprognostic (5.90e-3)" "unprognostic (1.14e-1)" "unprognostic (4.88e-2)" "unprognostic (1.03e-1)" PLEKHM1 KIAA0356 ENSG00000225190 "Pleckstrin homology and RUN domain containing M1" Q9Y4G2 17 45435900-45490758 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Autophagy, Protein transport, Transport" "Disease variant, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 29.0" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 19.8;Brain inhibitory neurons: 18.1;Choroid plexus epithelial cells: 17.1;Distal convoluted tubule cells: 28.1;Loop of henle epithelial cells: 26.9;Microglia: 20.2;Oligodendrocytes: 27.8;Papillary tip epithelial cells: 44.0;Podocytes: 27.4;Proximal tubule cells: 26.0;Renal collecting duct intercalated cells: 32.3;Renal collecting duct principal cells: 27.2;Renal connecting tubule cells: 30.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 10.0" "Lineage enriched" "Detected in many" 4 "granulocytes: 10.0" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025018, HPA039473" Approved Supported Vesicles NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 15: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 102: Non-specific - Mixed function" 27 Vesicles "HPA025018: , HPA039473: " "unprognostic (3.61e-2)" "unprognostic (1.92e-1)" "potential prognostic favorable (4.03e-6)" "unprognostic (2.47e-1)" "unprognostic (8.24e-2)" "unprognostic (7.49e-3)" "unprognostic (7.66e-2)" "unprognostic (2.37e-1)" "unprognostic (1.49e-1)" "unprognostic (1.80e-2)" "unprognostic (1.16e-3)" "unprognostic (1.49e-1)" "unprognostic (9.17e-2)" "unprognostic (1.59e-1)" "unprognostic (8.49e-2)" "unprognostic (2.17e-2)" "unprognostic (1.70e-1)" "unprognostic (4.53e-2)" "unprognostic (1.99e-2)" "unprognostic (2.77e-1)" "unprognostic (1.12e-1)" "unprognostic (2.56e-2)" "unprognostic (1.18e-1)" "unprognostic (4.43e-2)" "potential prognostic favorable (2.30e-4)" "unprognostic (1.62e-2)" "unprognostic (3.49e-2)" "unprognostic (1.45e-2)" "unprognostic (5.20e-2)" "unprognostic (1.21e-1)" PLEKHM2 KIAA0842 ENSG00000116786 "Pleckstrin homology and RUN domain containing M2" Q8IWE5 1 15684320-15734769 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 159.3" "Cell type enhanced" "Detected in all" "Neutrophils: 233.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032304 Approved NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 53: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 1 "HPA032304: " "unprognostic (5.64e-2)" "unprognostic (3.17e-1)" "unprognostic (1.08e-1)" "unprognostic (7.38e-2)" "unprognostic (3.74e-1)" "unprognostic (7.80e-2)" "unprognostic (1.48e-1)" "potential prognostic favorable (9.52e-4)" "unprognostic (1.91e-1)" "unprognostic (8.26e-2)" "unprognostic (1.02e-2)" "unprognostic (9.02e-2)" "unprognostic (7.86e-2)" "potential prognostic unfavorable (1.08e-8)" "unprognostic (8.07e-2)" "unprognostic (2.55e-1)" "unprognostic (1.04e-1)" "unprognostic (1.69e-2)" "unprognostic (2.29e-1)" "unprognostic (8.33e-3)" "unprognostic (1.45e-1)" "unprognostic (7.06e-2)" "unprognostic (1.85e-1)" "unprognostic (2.50e-2)" "unprognostic (1.44e-1)" "unprognostic (1.67e-3)" "unprognostic (3.42e-2)" "unprognostic (1.59e-1)" "unprognostic (1.71e-1)" "unprognostic (1.12e-1)" "unprognostic (3.73e-1)" PLEKHM3 "DAPR, PLEKHM1L" ENSG00000178385 "Pleckstrin homology domain containing M3" Q6ZWE6 2 207821288-208025527 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Neutrophils: 243.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035046 Uncertain Approved Vesicles,Cytosol NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 82: Dendritic cells - Antigen presentation" 7 Cytosol Vesicles "HPA035046: " "unprognostic (2.28e-1)" "unprognostic (3.67e-1)" "unprognostic (9.03e-2)" "unprognostic (2.20e-1)" "unprognostic (7.69e-3)" "unprognostic (2.30e-2)" "potential prognostic favorable (8.75e-6)" "unprognostic (6.15e-3)" "unprognostic (2.59e-1)" "unprognostic (4.68e-2)" "unprognostic (3.89e-3)" "unprognostic (2.10e-1)" "unprognostic (8.46e-2)" "unprognostic (6.47e-2)" "unprognostic (2.67e-3)" "unprognostic (7.43e-3)" "unprognostic (2.21e-1)" "unprognostic (2.56e-3)" "unprognostic (1.16e-1)" "unprognostic (1.22e-3)" "unprognostic (1.67e-1)" "unprognostic (5.20e-2)" "unprognostic (2.37e-1)" "unprognostic (7.10e-2)" PLEKHN1 DKFZP434H2010 ENSG00000187583 "Pleckstrin homology domain containing N1" Q494U1 1 966482-975865 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 23.9;esophagus: 58.4;skin 1: 48.4;vagina: 25.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 132.4;Epididymal basal cells: 49.8;Esophageal apical cells: 306.9;Esophageal basal cells: 42.0;Esophageal suprabasal cells: 144.5;Ocular epithelial cells: 46.0;Prostatic hillock cells: 46.2;Suprabasal keratinocytes: 74.0;Urothelial cells: 63.0" "Cell type enhanced" "Detected in single" "leukocyte: 1.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 24.7" "Prostate - Urothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA031741, HPA031742" Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 11 "Plasma membrane" Cytosol "HPA031741: , HPA031742: " "unprognostic (1.08e-1)" "unprognostic (1.58e-2)" "unprognostic (6.13e-2)" "unprognostic (2.85e-2)" "unprognostic (1.92e-1)" "unprognostic (1.09e-1)" "unprognostic (3.40e-2)" "potential prognostic unfavorable (1.17e-6)" "unprognostic (1.88e-1)" "unprognostic (7.21e-2)" "unprognostic (1.13e-2)" "unprognostic (1.37e-1)" "unprognostic (6.72e-2)" "unprognostic (2.03e-1)" "unprognostic (1.87e-1)" "unprognostic (2.90e-3)" "unprognostic (9.90e-2)" "unprognostic (1.05e-3)" "unprognostic (5.75e-2)" "unprognostic (3.76e-1)" "unprognostic (1.32e-1)" "unprognostic (3.77e-3)" "unprognostic (2.63e-1)" "unprognostic (1.25e-1)" "unprognostic (2.32e-2)" "unprognostic (1.68e-2)" PLEKHO1 "CKIP-1, OC120" ENSG00000023902 "Pleckstrin homology domain containing O1" Q53GL0 1 150149183-150164720 "Predicted intracellular proteins" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 189.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 185.5;cDC: 226.4;Early spermatids: 256.2;Late primary spermatocytes: 292.1;Late spermatids: 525.8;Megakaryocytes: 197.8;Platelets: 1194.6;Smooth muscle cells: 349.4;Vascular smooth muscle cells: 167.9" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 169.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Liver - Vascular endothelial cells, Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061018 Supported Mitochondria NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 15: Non-specific - Transcription" "Cluster 35: RS4;11 - Unknown function" "Cluster 47: Platelets - Hemostasis" 34 Mitochondria "HPA061018: " "unprognostic (3.84e-2)" "unprognostic (3.27e-3)" "unprognostic (2.17e-2)" "unprognostic (4.16e-2)" "unprognostic (5.47e-2)" "unprognostic (2.91e-1)" "unprognostic (3.86e-1)" "potential prognostic favorable (2.34e-4)" "unprognostic (1.26e-1)" "unprognostic (1.92e-1)" "potential prognostic unfavorable (6.27e-5)" "unprognostic (2.48e-1)" "unprognostic (2.07e-1)" "unprognostic (2.79e-2)" "unprognostic (4.31e-2)" "unprognostic (6.79e-2)" "unprognostic (5.63e-2)" "unprognostic (8.22e-2)" "unprognostic (1.32e-1)" "unprognostic (1.02e-1)" "unprognostic (8.57e-2)" "unprognostic (3.60e-2)" "unprognostic (3.44e-2)" "unprognostic (1.13e-1)" "unprognostic (3.69e-2)" "unprognostic (6.36e-2)" "unprognostic (3.19e-2)" "unprognostic (3.74e-2)" "unprognostic (1.78e-1)" "unprognostic (2.30e-1)" "unprognostic (4.13e-2)" PLEKHO2 "DKFZp761K2312, PLEKHQ1, PP1628, pp9099" ENSG00000241839 "Pleckstrin homology domain containing O2" Q8TD55 15 64841883-64868002 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 98.2" "Cell type enhanced" "Detected in some" "Early spermatids: 1.2;Myosatellite cells: 1.2;Neutrophils: 1.6;Retinal pigment epithelial cells: 4.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 27.1;granulocytes: 77.5;monocytes: 73.3" "Low cancer specificity" "Detected in all" "Pituitary gland - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040055 Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 97000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 19: Astrocytes - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" 5 "Plasma membrane, Cytosol" Nucleoplasm "HPA040055: " "unprognostic (1.16e-2)" "unprognostic (2.08e-1)" "unprognostic (9.14e-2)" "unprognostic (1.24e-1)" "unprognostic (7.73e-2)" "unprognostic (1.90e-1)" "unprognostic (1.55e-2)" "unprognostic (1.18e-1)" "unprognostic (3.48e-2)" "unprognostic (3.53e-1)" "unprognostic (4.86e-3)" "unprognostic (7.46e-3)" "unprognostic (3.67e-2)" "unprognostic (7.14e-2)" "unprognostic (1.67e-2)" "unprognostic (2.45e-2)" "unprognostic (1.74e-2)" "unprognostic (1.52e-2)" "unprognostic (3.09e-1)" "unprognostic (8.84e-3)" "unprognostic (1.27e-1)" "unprognostic (1.54e-1)" "unprognostic (1.59e-1)" "unprognostic (1.93e-2)" "unprognostic (1.08e-1)" "unprognostic (2.12e-2)" "unprognostic (2.29e-1)" "unprognostic (8.52e-2)" "unprognostic (4.19e-2)" "unprognostic (3.45e-2)" "unprognostic (3.06e-2)" PLEKHS1 "bA211N11.2, C10orf81, FLJ23537" ENSG00000148735 "Pleckstrin homology domain containing S1" Q5SXH7 10 113751262-113783429 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "breast: 23.2;cervix: 46.2;intestine: 34.6;pancreas: 25.6;salivary gland: 40.2" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 99.0;Lacrimal acinar cells: 109.6;Respiratory basal cells: 143.0;Respiratory ciliated cells: 268.1;Respiratory deuterosomal cells: 360.7;Respiratory secretory cells: 405.4;Salivary acinar cells: 103.6;Salivary duct cells: 143.8;Salivary ionocytes: 145.8;Submucosal glandular cells: 139.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 14.3;breast cancer: 16.2" "Kidney - Macrophages, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Skin - Eccrine sweat gland cells, Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA037583 Approved Vesicles,Centrosome NA NA "Cluster 60: Stomach - Digestion" "Cluster 53: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 3 Centrosome Vesicles "HPA037583: " "unprognostic (1.65e-1)" "unprognostic (3.11e-1)" "unprognostic (1.03e-2)" "unprognostic (2.05e-1)" "unprognostic (2.07e-2)" "unprognostic (1.46e-1)" "unprognostic (1.87e-2)" "unprognostic (8.06e-3)" "potential prognostic unfavorable (4.03e-4)" "potential prognostic unfavorable (1.50e-4)" "unprognostic (1.48e-2)" "unprognostic (2.45e-1)" "unprognostic (3.23e-1)" "unprognostic (5.45e-3)" "unprognostic (6.14e-2)" "unprognostic (2.17e-1)" "unprognostic (1.62e-1)" "unprognostic (5.76e-3)" "unprognostic (6.31e-2)" "unprognostic (1.07e-1)" "unprognostic (3.66e-2)" "unprognostic (4.21e-2)" "unprognostic (2.97e-3)" "unprognostic (1.80e-1)" PLET1 C11orf34 ENSG00000188771 "Placenta expressed transcript 1" Q6UQ28 11 112248153-112260860 "Essential proteins, Predicted membrane proteins" Differentiation "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "Epicardial cells: 61.4;Hepatic stellate cells: 19.4;Retinal bipolar cells: 24.7;Retinal ganglion cells: 34.8;Retinal horizontal cells: 32.1;Rod photoreceptor cells: 18.6" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in some" "midbrain: 2.3" HPA040237 Uncertain NA NA "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "HPA040237: " PLG ENSG00000122194 Plasminogen P00747 6 160702194-160754097 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis, Tissue remodeling" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "liver: 2479.5" "Group enriched" "Detected in some" 40 "Hepatocytes: 858.6;Proximal tubule cells: 318.4" "Low cell type specificity" "Detected in some" "Cancer enriched" "Detected in some" 41 "Liver Hepatocellular Carcinoma (TCGA): 397.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "liver cancer: 2.6" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000668, CAB016678, HPA021602, HPA048823, HPA053770" Supported Approved Vesicles "Secreted to blood" "Blood coagulation" NA NA 140000000000 72000000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 14: Neurons - Synaptic function" "Cluster 18: Liver cancer - Metabolism" "Cluster 88: Proximal tubular cells - Transmembrane transport" 16 Vesicles "CAB000668: , CAB016678: , HPA021602: , HPA048823: , HPA053770: " "potential prognostic favorable (5.22e-8)" "unprognostic (3.27e-3)" "unprognostic (2.54e-3)" "potential prognostic favorable (7.62e-4)" "potential prognostic unfavorable (5.74e-4)" PLGLB1 "PLGL, PRP-B" ENSG00000183281 "Plasminogen like B1" Q02325 2 87002559-87021852 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 62.7;liver: 234.5" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 11.1;Hepatocytes: 14.1;Loop of henle epithelial cells: 13.2;Papillary tip epithelial cells: 8.8;Podocytes: 21.4;Proximal tubule cells: 12.8;Renal collecting duct intercalated cells: 7.5;Renal collecting duct principal cells: 10.5;Renal connecting tubule cells: 10.7" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in all" 8 "Liver Hepatocellular Carcinoma (TCGA): 49.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" HPA053770 Approved Vesicles "Secreted to blood" "No annotated function" NA NA 1500000000 "Cluster 32: Basophils - Transcription" "Cluster 53: Liver - Plasma proteins" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 59: Leukemia - T-cell receptor" "Cluster 105: Non-specific - Mixed function" Vesicles "HPA053770: " "unprognostic (8.16e-2)" "unprognostic (3.70e-2)" "unprognostic (2.91e-2)" "unprognostic (4.47e-2)" "unprognostic (2.15e-1)" "unprognostic (8.22e-2)" "unprognostic (2.43e-3)" "potential prognostic favorable (5.53e-4)" "unprognostic (1.06e-1)" "potential prognostic unfavorable (4.51e-5)" "unprognostic (4.11e-2)" "unprognostic (2.54e-1)" "unprognostic (1.48e-2)" "potential prognostic favorable (7.87e-4)" "unprognostic (5.42e-2)" "unprognostic (6.06e-2)" "unprognostic (3.11e-1)" "unprognostic (2.07e-2)" "unprognostic (1.55e-1)" "unprognostic (3.61e-3)" "unprognostic (4.79e-3)" "unprognostic (9.61e-3)" "unprognostic (6.66e-2)" "unprognostic (1.74e-1)" "unprognostic (3.07e-2)" "unprognostic (6.64e-2)" "unprognostic (1.96e-1)" "unprognostic (3.90e-1)" "unprognostic (2.32e-1)" "unprognostic (8.65e-3)" PLGLB2 PLGP1 ENSG00000125551 "Plasminogen like B2" Q02325 2 87748087-87759476 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 48 "liver: 122.6" "Cell type enhanced" "Detected in single" "Podocytes: 1.5" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 31 "Liver Hepatocellular Carcinoma (TCGA): 20.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" HPA053770 Approved Vesicles "Secreted to blood" "No annotated function" NA NA 1500000000 "Cluster 53: Liver - Plasma proteins" "Cluster 15: Non-specific - Transcription" "Cluster 59: Leukemia - T-cell receptor" "Cluster 105: Non-specific - Mixed function" Vesicles "HPA053770: " "unprognostic (5.84e-2)" "unprognostic (8.89e-2)" "unprognostic (1.31e-1)" "unprognostic (1.26e-2)" "potential prognostic favorable (7.87e-4)" "potential prognostic unfavorable (7.40e-4)" "unprognostic (1.56e-1)" PLGRKT "AD025, C9orf46, FLJ14688, MDS030, Plg-RKT" ENSG00000107020 "Plasminogen receptor with a C-terminal lysine" Q9HBL7 9 5357971-5437925 "Predicted membrane proteins" "Chemotaxis, Inflammatory response, Plasminogen activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 163.8;Enterocytes: 177.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 245.6" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008214, HPA011144" Supported Uncertain Mitochondria NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 3 Mitochondria "HPA008214: , HPA011144: " "unprognostic (3.93e-2)" "potential prognostic favorable (7.31e-4)" "unprognostic (2.15e-3)" "unprognostic (2.49e-1)" "unprognostic (1.70e-1)" "unprognostic (1.60e-1)" "unprognostic (2.64e-3)" "unprognostic (1.60e-2)" "unprognostic (7.23e-3)" "potential prognostic favorable (3.07e-4)" "unprognostic (1.93e-1)" "unprognostic (1.00e-3)" "unprognostic (4.94e-2)" "unprognostic (8.32e-2)" "unprognostic (1.59e-2)" "unprognostic (2.57e-2)" "unprognostic (1.54e-1)" "potential prognostic favorable (9.40e-4)" "unprognostic (5.19e-2)" "unprognostic (4.81e-3)" "unprognostic (1.41e-2)" "unprognostic (5.92e-2)" "unprognostic (3.83e-2)" "unprognostic (2.46e-1)" "unprognostic (4.92e-2)" "unprognostic (3.46e-2)" "unprognostic (8.07e-2)" "unprognostic (3.12e-1)" "unprognostic (5.57e-2)" PLIN1 PLIN ENSG00000166819 "Perilipin 1" O60240 15 89664367-89679427 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "adipose tissue: 898.1;breast: 459.5" "Cell type enriched" "Detected in some" 11 "Adipocytes: 879.6" "Cell type enhanced" "Detected in some" "astrocyte: 11.2" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 20.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Minor Salivary Gland - Adipocytes (Minor salivary gland), Skin - Adipocytes (Skin), Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA024299, CAB033821, CAB037333" Enhanced Uncertain Peroxisomes NA NA 29000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 39: Astrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 89: Adipocytes - Lipid metabolism" 5 Peroxisomes "CAB033821: , CAB037333: , HPA024299: " "unprognostic (8.54e-3)" "unprognostic (6.86e-2)" "unprognostic (6.59e-3)" "unprognostic (1.92e-1)" "unprognostic (3.74e-3)" "unprognostic (4.55e-2)" "unprognostic (8.33e-2)" "unprognostic (2.21e-2)" "unprognostic (2.66e-3)" "unprognostic (8.59e-2)" "unprognostic (2.47e-2)" "unprognostic (1.57e-1)" "unprognostic (1.99e-2)" "unprognostic (2.87e-2)" "unprognostic (1.45e-1)" "unprognostic (1.57e-1)" "unprognostic (5.71e-2)" PLIN2 "ADFP, ADRP" ENSG00000147872 "Perilipin 2" Q99541 9 19108375-19149290 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 617.1;liver: 845.8" "Cell type enhanced" "Detected in many" "Breast lactating cells: 2322.0;Extravillous trophoblasts: 1144.3;Hepatocytes: 722.0;Mast cells: 854.8;Migrating cytotrophoblasts: 629.9;monocytes: 900.9;Syncytiotrophoblasts: 2942.9" "Cell type enhanced" "Detected in all" "endothelial cell: 30.0" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 855.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 777.5;eosinophil: 583.3" "Lineage enriched" "Detected in all" 5 "granulocytes: 777.5" "Cancer enhanced" "Detected in all" "Kidney cancer: 271.9" "Pituitary gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016607, CAB037331, CAB080243, CAB080244, CAB080245" Supported Supported "Lipid droplets" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 12: Non-specific - Vasculature" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." 11 "Lipid droplets" "CAB037331: , CAB080243: , CAB080244: , CAB080245: , HPA016607: " "unprognostic (3.65e-3)" "unprognostic (2.65e-1)" "unprognostic (2.24e-1)" "unprognostic (1.97e-2)" "unprognostic (5.94e-2)" "unprognostic (5.71e-2)" "unprognostic (2.81e-2)" "unprognostic (1.21e-1)" "unprognostic (4.97e-2)" "unprognostic (7.45e-2)" "potential prognostic favorable (3.60e-7)" "unprognostic (3.42e-2)" "unprognostic (1.54e-1)" "unprognostic (5.71e-3)" "unprognostic (6.25e-2)" "unprognostic (9.24e-3)" "potential prognostic unfavorable (4.03e-5)" "unprognostic (9.01e-3)" "unprognostic (5.34e-2)" "unprognostic (6.22e-2)" "unprognostic (1.88e-1)" "unprognostic (6.69e-2)" "unprognostic (4.08e-2)" "unprognostic (9.80e-2)" "unprognostic (2.80e-1)" "unprognostic (2.89e-2)" "unprognostic (7.90e-2)" "potential prognostic unfavorable (3.43e-4)" "unprognostic (2.76e-1)" "unprognostic (1.85e-1)" "unprognostic (1.91e-3)" PLIN3 "M6PRBP1, PP17, TIP47" ENSG00000105355 "Perilipin 3" O60664 19 4838341-4867694 "FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transport "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 714.7;Enterocytes: 342.6;Esophageal apical cells: 1077.1;Esophageal suprabasal cells: 323.7;Suprabasal keratinocytes: 273.5;Syncytiotrophoblasts: 255.2" "Cell type enhanced" "Detected in many" "oligodendrocyte: 30.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Macrophages, Adrenal gland - Adrenal cortex cells, Colon - Macrophages, Heart muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006427, HPA066538" Uncertain Supported "Lipid droplets" NA Yes 3800000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 72: Neuronal - Signal transduction" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 26 "Lipid droplets" "HPA006427: , HPA066538: " "unprognostic (1.82e-1)" "unprognostic (1.19e-1)" "unprognostic (1.81e-1)" "unprognostic (6.64e-3)" "unprognostic (3.68e-2)" "unprognostic (2.57e-1)" "unprognostic (2.21e-1)" "unprognostic (1.02e-3)" "unprognostic (4.67e-2)" "unprognostic (2.24e-2)" "validated prognostic unfavorable (6.78e-6)" "validated prognostic unfavorable (2.69e-5)" "unprognostic (2.61e-1)" "validated prognostic unfavorable (7.88e-5)" "validated prognostic unfavorable (6.49e-4)" "validated prognostic unfavorable (1.57e-7)" "validated prognostic unfavorable (1.23e-4)" "unprognostic (7.40e-2)" "unprognostic (9.05e-2)" "unprognostic (1.74e-1)" "unprognostic (1.14e-1)" "unprognostic (4.35e-2)" "unprognostic (3.59e-2)" "unprognostic (9.31e-2)" "unprognostic (5.98e-2)" "unprognostic (6.59e-2)" "unprognostic (4.67e-3)" "unprognostic (2.52e-1)" "unprognostic (2.29e-1)" "unprognostic (3.71e-1)" "unprognostic (1.17e-3)" PLIN4 "KIAA1881, S3-12" ENSG00000167676 "Perilipin 4" Q96Q06 19 4502192-4518486 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 715.6;breast: 303.4;skeletal muscle: 235.5" "Cell type enriched" "Detected in many" 9 "Adipocytes: 518.0" "Group enriched" "Detected in some" 4 "astrocyte: 21.7;Bergmann glia: 6.0;ependymal cell: 6.1" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 15.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 4.6" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Minor Salivary Gland - Adipocytes (Minor salivary gland), Prostate - Smooth muscle cells, Skin - Adipocytes (Skin), Spleen - Neutrophils_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" "HPA044682, HPA054657" Enhanced Enhanced "Lipid droplets,Plasma membrane,Cytosol" NA NA 130000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 19: Astrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 89: Adipocytes - Lipid metabolism" "Plasma membrane, Cytosol" "Lipid droplets" "HPA044682: , HPA054657: " "unprognostic (6.31e-2)" "unprognostic (4.31e-2)" "potential prognostic favorable (3.46e-4)" "unprognostic (2.70e-1)" "unprognostic (7.75e-2)" "unprognostic (2.96e-1)" "unprognostic (1.35e-1)" "unprognostic (1.36e-1)" "potential prognostic favorable (8.34e-4)" "unprognostic (1.14e-1)" "unprognostic (8.14e-3)" "unprognostic (5.45e-2)" "unprognostic (1.81e-1)" "unprognostic (1.89e-2)" "unprognostic (1.71e-2)" "unprognostic (4.13e-2)" "unprognostic (2.07e-2)" "unprognostic (1.37e-2)" "unprognostic (1.52e-1)" "unprognostic (7.04e-3)" "unprognostic (5.68e-2)" "unprognostic (2.28e-3)" PLIN5 "LSDA5, LSDP5, MLDP, OXPAT" ENSG00000214456 "Perilipin 5" Q00G26 19 4522531-4535224 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 199.6;skeletal muscle: 142.3" "Cell type enhanced" "Detected in many" "Adipocytes: 150.3;Hepatocytes: 148.8;Lacrimal acinar cells: 177.5;Myonuclei: 177.4;Neutrophils: 156.4;Pancreatic acinar cells: 157.0;Proximal tubule cells: 85.7;Salivary acinar cells: 155.4" "Cell type enhanced" "Detected in many" "astrocyte: 56.0;Bergmann glia: 27.5;choroid plexus epithelial cell: 29.8" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 23.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "neutrophil: 13.8" "Lineage enriched" "Detected in single" 23 "granulocytes: 13.8" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Skin - Sebaceous gland cells, Spleen - Neutrophils_2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA077050 Supported "Vesicles,Lipid droplets" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 70: Non-specific - Protein processing" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 11: Neuronal - Sensory perception" "Cluster 55: Myocytes - Oxidative muscle function" 2 "Vesicles, Lipid droplets" "HPA077050: " "unprognostic (5.84e-3)" "unprognostic (3.87e-3)" "unprognostic (4.04e-2)" "unprognostic (1.01e-1)" "potential prognostic favorable (3.26e-4)" "unprognostic (1.26e-2)" "unprognostic (1.97e-1)" "potential prognostic unfavorable (2.98e-4)" "unprognostic (7.60e-2)" "unprognostic (2.38e-2)" "unprognostic (3.51e-3)" "potential prognostic favorable (5.40e-4)" "unprognostic (1.09e-3)" "unprognostic (1.41e-2)" "unprognostic (5.95e-2)" "unprognostic (2.30e-2)" "unprognostic (6.41e-2)" "unprognostic (2.50e-1)" "unprognostic (3.33e-1)" "unprognostic (1.97e-3)" "unprognostic (2.13e-1)" "unprognostic (1.18e-1)" "unprognostic (8.62e-2)" "unprognostic (1.18e-1)" "unprognostic (1.30e-1)" "unprognostic (2.32e-2)" PLK1 PLK ENSG00000166851 "Polo like kinase 1" P53350 16 23677656-23690367 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 30.2;lymphoid tissue: 40.9;testis: 31.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 36.7;Differentiating spermatogonia: 29.9;Early spermatids: 110.7;Enteric transient amplifying cells: 55.1;Erythrocyte progenitors: 39.7;Esophageal basal cells: 41.5;Extravillous trophoblasts: 58.9;Hofbauer cells: 32.1;Late primary spermatocytes: 180.3;Megakaryocyte progenitors: 36.9;Migrating cytotrophoblasts: 51.4;Monocyte progenitors: 108.1;Paneth cells: 30.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 5 "T-reg: 5.7" "Lineage enriched" "Detected in many" 5 "T-cells: 5.7" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA051638, HPA053229" Approved NA Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 38: Non-specific - Transcription" "Cluster 27: Non-specific - Cell proliferation" 319 "HPA051638: , HPA053229: " "unprognostic (1.02e-2)" "unprognostic (4.02e-3)" "unprognostic (2.84e-2)" "unprognostic (3.93e-2)" "unprognostic (4.18e-2)" "unprognostic (9.25e-2)" "unprognostic (1.85e-1)" "unprognostic (4.12e-2)" "unprognostic (4.08e-2)" "potential prognostic unfavorable (4.16e-6)" "validated prognostic unfavorable (4.72e-11)" "validated prognostic unfavorable (5.99e-8)" "potential prognostic unfavorable (1.05e-8)" "validated prognostic unfavorable (1.32e-7)" "validated prognostic unfavorable (9.70e-9)" "validated prognostic unfavorable (5.65e-7)" "validated prognostic unfavorable (4.41e-4)" "unprognostic (7.91e-2)" "unprognostic (1.69e-1)" "unprognostic (2.59e-1)" "unprognostic (1.70e-2)" "potential prognostic unfavorable (4.35e-4)" "unprognostic (3.41e-3)" "unprognostic (1.84e-1)" "unprognostic (4.90e-2)" "unprognostic (3.72e-1)" "unprognostic (6.94e-2)" "unprognostic (1.09e-1)" "unprognostic (1.10e-1)" "unprognostic (1.98e-1)" "unprognostic (1.08e-1)" PLK2 SNK ENSG00000145632 "Polo like kinase 2" Q9NYY3 5 58453982-58460139 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 247.1;Breast secretory cells: 163.6;Endometrial glandular cells: 159.4;Endometrial luminal cells: 165.9;Endometrial secretory cells: 205.2;Epididymal basal cells: 262.5;Extravillous trophoblasts: 389.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "NK-cell: 9.1" "Lineage enriched" "Detected in many" 4 "NK-cells: 9.1" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts, Spleen - Endothelial cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009624, HPA069329" Approved Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 41: Basophils - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 51: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 20: Non-specific - Transcription regulation" 7 "Nucleoplasm, Mitochondria, Cytosol" "CAB009624: , HPA069329: " "unprognostic (7.56e-2)" "unprognostic (5.58e-2)" "unprognostic (2.28e-1)" "unprognostic (2.30e-2)" "unprognostic (3.38e-1)" "unprognostic (6.25e-2)" "unprognostic (1.24e-3)" "unprognostic (5.17e-1)" "unprognostic (8.13e-2)" "unprognostic (7.04e-2)" "unprognostic (1.32e-2)" "unprognostic (1.56e-2)" "unprognostic (3.63e-2)" "unprognostic (4.64e-2)" "unprognostic (2.01e-3)" "unprognostic (1.43e-1)" "unprognostic (5.84e-3)" "unprognostic (1.69e-1)" "unprognostic (6.50e-2)" "unprognostic (2.77e-2)" "unprognostic (7.19e-3)" "unprognostic (1.78e-1)" "unprognostic (3.90e-3)" "unprognostic (3.29e-1)" "unprognostic (1.16e-1)" "unprognostic (6.32e-2)" "unprognostic (6.43e-2)" "unprognostic (1.86e-1)" "unprognostic (2.51e-1)" "unprognostic (2.13e-1)" "unprognostic (2.43e-1)" PLK3 "CNK, FNK, PRK" ENSG00000173846 "Polo like kinase 3" Q9H4B4 1 44800377-44805990 "Enzymes, Predicted intracellular proteins" "Apoptosis, Cell cycle, DNA damage" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 121.8;Esophageal apical cells: 391.7;Neutrophils: 325.3" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 27.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060318 Enhanced NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 13 "HPA060318: " "unprognostic (5.26e-2)" "unprognostic (4.94e-2)" "unprognostic (3.86e-2)" "unprognostic (9.98e-2)" "unprognostic (1.74e-1)" "unprognostic (4.03e-1)" "unprognostic (1.04e-2)" "unprognostic (8.67e-3)" "unprognostic (2.53e-2)" "unprognostic (1.26e-1)" "unprognostic (1.69e-1)" "unprognostic (5.71e-2)" "unprognostic (2.17e-1)" "unprognostic (5.13e-2)" "unprognostic (4.73e-2)" "unprognostic (6.38e-2)" "unprognostic (3.69e-2)" "unprognostic (1.24e-3)" "unprognostic (3.49e-1)" "unprognostic (4.42e-2)" "unprognostic (7.58e-3)" "unprognostic (5.76e-3)" "unprognostic (5.11e-3)" "unprognostic (3.00e-1)" "unprognostic (1.15e-1)" "unprognostic (5.06e-3)" "unprognostic (2.44e-3)" "unprognostic (6.18e-2)" "unprognostic (8.92e-2)" "unprognostic (2.19e-1)" "potential prognostic unfavorable (6.00e-5)" PLK4 "Sak, STK18" ENSG00000142731 "Polo like kinase 4" O00444 4 127880893-127899224 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 21.3;lymphoid tissue: 13.4;testis: 21.2" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 28.7;Early spermatids: 63.2;Erythrocyte progenitors: 61.9;Late primary spermatocytes: 104.4;Late spermatids: 139.2;Megakaryocyte progenitors: 34.8;Monocyte progenitors: 47.4;Neutrophil progenitors: 32.2;Respiratory deuterosomal cells: 69.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017327, HPA035026, HPA043198" Approved Supported Centrosome,Cytosol NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 24: Neurons - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Non-specific - Cell proliferation" 42 Centrosome Cytosol "HPA017327: , HPA035026: , HPA043198: " "unprognostic (2.64e-2)" "unprognostic (2.17e-1)" "unprognostic (7.67e-2)" "unprognostic (2.30e-1)" "unprognostic (3.52e-3)" "unprognostic (3.23e-1)" "unprognostic (3.77e-1)" "unprognostic (2.01e-2)" "unprognostic (3.68e-1)" "potential prognostic unfavorable (1.32e-5)" "unprognostic (3.64e-2)" "unprognostic (5.21e-2)" "unprognostic (3.50e-2)" "validated prognostic unfavorable (4.39e-5)" "validated prognostic unfavorable (1.10e-4)" "validated prognostic unfavorable (9.07e-5)" "validated prognostic unfavorable (3.77e-4)" "unprognostic (2.70e-1)" "unprognostic (2.25e-1)" "unprognostic (1.13e-1)" "unprognostic (3.65e-2)" "unprognostic (1.10e-3)" "potential prognostic unfavorable (6.31e-4)" "unprognostic (2.17e-2)" "unprognostic (1.09e-3)" "unprognostic (7.91e-2)" "unprognostic (3.68e-2)" "unprognostic (4.86e-2)" "unprognostic (2.56e-1)" "unprognostic (2.63e-2)" "unprognostic (6.97e-2)" PLK5 "PLK5P, SgK384ps" ENSG00000185988 "Polo like kinase 5 (inactive)" Q496M5 19 1508023-1536046 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 32.4;cervix: 8.9" "Cell type enhanced" "Detected in many" "Astrocytes: 31.4;Cardiomyocytes: 68.0;Choroid plexus epithelial cells: 24.2;Leydig cells: 76.6;Müller glia: 38.5;Myonuclei: 39.0;Peritubular myoid cells: 115.7;Retinal amacrine cells: 25.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Smooth muscle cells" "Region enhanced" "Detected in all" "cerebellum: 42.0" "Group enriched" "Detected in many" 5 "cerebellum: 57.4;cerebral cortex: 15.3;hippocampal formation: 20.1" HPA035024 Enhanced NA NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 15: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 94: Gonadal somatic cells - Mixed function" "HPA035024: " "unprognostic (1.21e-1)" "unprognostic (1.46e-1)" "unprognostic (9.07e-2)" PLLP "PMLP, TM4SF11" ENSG00000102934 Plasmolipin Q9Y342 16 57248547-57284672 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 200.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 222.6;Cholangiocytes: 173.2;Endometrial luminal cells: 214.5;Enterocytes: 187.5;Epididymal clear cells: 185.8;Oligodendrocyte progenitor cells: 234.0;Oligodendrocytes: 357.8" "Group enriched" "Detected in all" 16 "committed oligodendrocyte precursor: 170.2;endothelial cell: 157.7;oligodendrocyte: 376.6;oligodendrocyte precursor cell: 256.0" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 206.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "naive CD4 T-cell: 14.5;naive CD8 T-cell: 5.7" "Lineage enriched" "Detected in many" 8 "T-cells: 14.5" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 47.5" "Adipose visceral - Mesothelial cells, Liver - Hepatocytes, Lung - Alveolar cells type 1, Spleen - Endothelial cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041862 Enhanced NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 18: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 33 "HPA041862: " "unprognostic (1.73e-2)" "unprognostic (1.76e-2)" "unprognostic (5.39e-2)" "unprognostic (1.00e-2)" "unprognostic (9.30e-2)" "unprognostic (3.67e-1)" "unprognostic (1.74e-1)" "unprognostic (1.72e-1)" "unprognostic (3.07e-2)" "unprognostic (1.62e-2)" "validated prognostic favorable (5.37e-8)" "validated prognostic favorable (1.99e-4)" "unprognostic (1.86e-3)" "unprognostic (2.19e-2)" "unprognostic (9.72e-3)" "unprognostic (6.46e-2)" "unprognostic (3.53e-3)" "unprognostic (1.65e-1)" "unprognostic (5.80e-2)" "unprognostic (2.34e-1)" "unprognostic (5.44e-3)" "unprognostic (7.13e-3)" "unprognostic (4.04e-2)" "unprognostic (1.27e-1)" "unprognostic (7.44e-2)" "unprognostic (2.56e-2)" "unprognostic (5.65e-2)" "unprognostic (4.03e-2)" "unprognostic (7.88e-2)" "unprognostic (1.41e-1)" "unprognostic (8.57e-2)" PLN "CMD1P, PLB" ENSG00000198523 Phospholamban P26678 6 118548296-118561716 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 1463.0;skeletal muscle: 474.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 166.5;Early spermatids: 103.1;Late primary spermatocytes: 119.0;Myonuclei: 207.3;Smooth muscle cells: 561.2;Thymic myoid cells: 65.3;Vascular smooth muscle cells: 698.5" "Cell type enriched" "Detected in all" 16 "vascular associated smooth muscle cell: 197.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "skin cancer: 4.9" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Adrenal gland - Smooth muscle cells, Breast - Endothelial cells, Heart muscle - Cardiomyocytes, Kidney - Fibroblasts, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Spleen - Smooth muscle cells, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB005597, HPA026900" Enhanced NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 69: Skin cancer - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 53 "CAB005597: , HPA026900: " "unprognostic (1.21e-2)" "unprognostic (2.69e-1)" "unprognostic (2.01e-1)" "unprognostic (3.26e-2)" "unprognostic (1.26e-2)" "unprognostic (1.25e-2)" "unprognostic (3.43e-1)" "unprognostic (4.73e-2)" "unprognostic (4.25e-2)" "unprognostic (1.69e-1)" "validated prognostic favorable (3.91e-4)" "validated prognostic favorable (7.62e-4)" "unprognostic (1.10e-3)" "unprognostic (1.32e-1)" "unprognostic (4.06e-1)" "unprognostic (2.58e-1)" "unprognostic (6.18e-3)" "potential prognostic unfavorable (7.75e-5)" "unprognostic (1.49e-1)" "unprognostic (5.23e-3)" "unprognostic (2.60e-1)" "unprognostic (2.27e-2)" "unprognostic (1.15e-2)" "unprognostic (1.64e-3)" "unprognostic (2.55e-1)" "unprognostic (1.98e-1)" "unprognostic (8.75e-3)" PLOD1 "LH1, LLH, PLOD" ENSG00000083444 "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1" Q02809 1 11934205-11975538 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 101.8;Extravillous trophoblasts: 364.7;Hepatic stellate cells: 90.4;Myosatellite cells: 80.2" "Group enriched" "Detected in all" 5 "fibroblast: 72.1;pericyte: 135.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049137, HPA055799" Uncertain Uncertain Nucleoplasm,Vesicles "Intracellular and membrane" Enzyme NA NA 2200000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 75: Ovary - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 26 Vesicles Nucleoplasm "HPA049137: , HPA055799: " "unprognostic (4.86e-2)" "unprognostic (8.91e-3)" "unprognostic (1.06e-1)" "potential prognostic unfavorable (5.08e-4)" "unprognostic (4.19e-1)" "unprognostic (9.91e-2)" "unprognostic (5.56e-3)" "unprognostic (5.35e-2)" "unprognostic (4.15e-3)" "unprognostic (2.14e-2)" "unprognostic (1.92e-2)" "potential prognostic unfavorable (6.48e-4)" "unprognostic (9.42e-3)" "validated prognostic unfavorable (2.13e-4)" "validated prognostic unfavorable (2.98e-5)" "validated prognostic unfavorable (1.49e-4)" "validated prognostic unfavorable (3.28e-5)" "unprognostic (3.85e-2)" "unprognostic (3.78e-1)" "unprognostic (4.94e-2)" "unprognostic (1.52e-1)" "unprognostic (2.08e-3)" "unprognostic (2.13e-2)" "unprognostic (3.18e-1)" "unprognostic (1.64e-1)" "unprognostic (4.67e-2)" "unprognostic (1.32e-1)" "unprognostic (1.09e-1)" "unprognostic (4.58e-1)" "unprognostic (1.47e-2)" "unprognostic (1.86e-1)" PLOD2 "LH2, TLH" ENSG00000152952 "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2" O00469 3 146035139-146163725 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Dioxygenase, Oxidoreductase" "Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Pancreatic acinar cells: 1732.9" "Cell type enhanced" "Detected in all" "astrocyte: 241.5;Bergmann glia: 211.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Kidney cancer: 285.7" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Minor Salivary Gland - Minor salivary glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025898, HPA069126" Approved Uncertain Nucleoli,Cytosol "Intracellular and membrane" Enzyme NA NA 9200 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 39: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 13 "Nucleoli, Cytosol" "CAB025898: , HPA069126: " "unprognostic (8.45e-2)" "unprognostic (4.15e-2)" "unprognostic (1.32e-1)" "potential prognostic unfavorable (2.66e-4)" "unprognostic (1.57e-1)" "unprognostic (2.46e-1)" "unprognostic (8.82e-3)" "unprognostic (2.80e-3)" "unprognostic (1.90e-3)" "potential prognostic unfavorable (1.01e-5)" "validated prognostic unfavorable (1.57e-8)" "validated prognostic unfavorable (2.44e-4)" "unprognostic (5.54e-3)" "validated prognostic unfavorable (3.09e-9)" "validated prognostic unfavorable (2.42e-5)" "validated prognostic unfavorable (2.93e-4)" "validated prognostic unfavorable (1.01e-6)" "unprognostic (1.21e-1)" "unprognostic (9.86e-3)" "unprognostic (6.75e-2)" "unprognostic (2.46e-2)" "unprognostic (3.15e-3)" "unprognostic (1.57e-2)" "unprognostic (4.39e-1)" "unprognostic (2.78e-1)" "unprognostic (3.39e-2)" "unprognostic (2.82e-2)" "potential prognostic unfavorable (2.56e-4)" "unprognostic (4.53e-2)" "unprognostic (1.33e-1)" "unprognostic (6.45e-2)" PLOD3 LH3 ENSG00000106397 "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3" O60568 7 101205977-101218420 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Dioxygenase, Glycosyltransferase, Multifunctional enzyme, Oxidoreductase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 74.7;Extravillous trophoblasts: 115.0;Melanocytes: 110.4;Schwann cells: 80.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 441.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 4 "dendritic cells: 20.3;monocytes: 22.6;T-cells: 12.6" "Cancer enhanced" "Detected in all" "skin cancer: 375.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075391 Approved "Secreted to extracellular matrix" Enzyme NA NA 520000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 69: Skin cancer - ECM organization" "Cluster 61: Schwann cells & Melanocytes - Mixed function" 41 "HPA075391: " "unprognostic (2.20e-1)" "unprognostic (1.66e-1)" "unprognostic (2.22e-1)" "potential prognostic unfavorable (2.58e-6)" "unprognostic (2.95e-2)" "potential prognostic unfavorable (6.82e-4)" "unprognostic (8.53e-3)" "potential prognostic unfavorable (5.16e-4)" "unprognostic (1.88e-2)" "unprognostic (1.76e-3)" "unprognostic (1.76e-2)" "unprognostic (5.35e-3)" "unprognostic (1.16e-1)" "unprognostic (3.12e-3)" "unprognostic (1.51e-3)" "unprognostic (1.02e-2)" "unprognostic (5.12e-3)" "unprognostic (3.47e-2)" "unprognostic (2.53e-1)" "unprognostic (4.80e-2)" "unprognostic (2.14e-1)" "unprognostic (1.23e-1)" "potential prognostic unfavorable (7.18e-4)" "unprognostic (2.90e-1)" "potential prognostic unfavorable (1.86e-4)" "unprognostic (2.55e-1)" "unprognostic (1.27e-2)" "unprognostic (3.88e-1)" "unprognostic (1.14e-1)" "unprognostic (6.74e-3)" "unprognostic (2.56e-2)" PLP1 "GPM6C, PLP, SPG2" ENSG00000123560 "Proteolipid protein 1" P60201 X 103773718-103792619 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cancer-related genes, Disease variant, Hereditary spastic paraplegia, Leukodystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 53 "brain: 10196.4" "Cell type enriched" "Detected in some" 5 "Oligodendrocytes: 5518.7" "Group enriched" "Detected in all" 32 "committed oligodendrocyte precursor: 2316.0;oligodendrocyte: 6763.0" "Group enriched" "Detected in many" 23 "Glioblastoma Multiforme (TCGA): 510.0;Skin Cutaneous Melanoma (TCGA): 248.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "skin cancer: 239.8" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Minor Salivary Gland - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004128 Enhanced NA NA 140000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 69: Skin cancer - ECM organization" "Cluster 80: Oligodendrocytes - Myelination" 8 "HPA004128: " "unprognostic (1.94e-1)" "unprognostic (2.51e-3)" "unprognostic (8.53e-2)" "unprognostic (1.37e-1)" "unprognostic (1.06e-3)" "unprognostic (2.25e-2)" "unprognostic (7.12e-2)" "unprognostic (2.36e-1)" "unprognostic (7.42e-2)" "unprognostic (5.97e-2)" "unprognostic (5.15e-2)" "unprognostic (6.13e-3)" PLP2 "A4, A4-LSB, MGC126187" ENSG00000102007 "Proteolipid protein 2" Q04941 X 49171898-49175235 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 437.7;Esophageal apical cells: 1071.2;Esophageal basal cells: 1130.9;Esophageal suprabasal cells: 1311.4;pDCs: 397.7;Suprabasal keratinocytes: 503.8" "Cell type enhanced" "Detected in many" "leukocyte: 36.6;vascular associated smooth muscle cell: 38.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skin - Keratinocyte (other), Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042415 Approved NA NA 80000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 12: Non-specific - Vasculature" "Cluster 36: Non-specific - mRNA processing" "Cluster 85: Squamous epithelial cells - Keratinization" 59 "HPA042415: " "unprognostic (5.90e-2)" "unprognostic (3.44e-1)" "unprognostic (7.74e-2)" "unprognostic (1.97e-1)" "unprognostic (3.60e-2)" "unprognostic (3.39e-3)" "unprognostic (1.45e-2)" "potential prognostic unfavorable (3.35e-4)" "unprognostic (3.35e-2)" "unprognostic (5.34e-2)" "potential prognostic unfavorable (1.70e-5)" "unprognostic (1.46e-3)" "unprognostic (1.71e-3)" "potential prognostic unfavorable (3.69e-4)" "unprognostic (1.70e-2)" "unprognostic (2.65e-3)" "potential prognostic unfavorable (2.07e-5)" "unprognostic (5.70e-3)" "unprognostic (2.31e-1)" "unprognostic (2.31e-1)" "unprognostic (5.12e-2)" "unprognostic (9.07e-3)" "unprognostic (4.15e-3)" "unprognostic (2.30e-1)" "unprognostic (2.86e-2)" "unprognostic (2.35e-1)" "unprognostic (5.48e-2)" "unprognostic (1.28e-1)" "unprognostic (4.53e-1)" "unprognostic (9.51e-3)" "unprognostic (5.12e-2)" PLPBP PROSC ENSG00000147471 "Pyridoxal phosphate binding protein" O94903 8 37762595-37779768 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017033, HPA023646, HPA023733" Approved Enhanced Cytosol NA NA 58000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 40: Non-specific - Unknown function" "Cluster 62: Smooth muscle cells - Muscle contraction" 5 Cytosol "CAB017033: , HPA023646: , HPA023733: " "unprognostic (1.22e-3)" "unprognostic (3.28e-3)" "unprognostic (1.19e-1)" "unprognostic (2.64e-2)" "unprognostic (8.70e-2)" "unprognostic (8.48e-2)" "unprognostic (3.92e-1)" "unprognostic (3.59e-3)" "unprognostic (2.20e-2)" "validated prognostic favorable (1.69e-7)" "validated prognostic favorable (2.04e-4)" "unprognostic (9.91e-2)" "unprognostic (6.64e-2)" "unprognostic (1.21e-1)" "unprognostic (6.46e-2)" "unprognostic (6.33e-2)" "unprognostic (1.43e-2)" "unprognostic (1.62e-1)" "unprognostic (1.50e-2)" "unprognostic (7.81e-2)" "unprognostic (7.38e-2)" "unprognostic (3.12e-2)" "unprognostic (3.96e-2)" "unprognostic (2.18e-1)" "unprognostic (1.12e-1)" "unprognostic (2.86e-1)" "unprognostic (1.26e-1)" "unprognostic (3.55e-1)" "unprognostic (3.67e-1)" PLPP1 "LPP1, PAP-2a, PPAP2A" ENSG00000067113 "Phospholipid phosphatase 1" O14494 5 55424854-55534969 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Prostatic glandular cells: 7829.4" "Cell type enhanced" "Detected in all" "endothelial cell: 1275.2" "Group enriched" "Detected in all" 4 "Kidney Renal Clear Cell Carcinoma (TCGA): 226.7;Prostate Adenocarcinoma (TCGA): 555.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "prostate cancer: 117.5" "Breast - Endothelial cells, Prostate - Prostate glandular cells, Spleen - Fibroblasts_2, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033331, HPA047815" Enhanced Supported "Plasma membrane" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 30: White matter - Myelination" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 7 "Plasma membrane" "CAB033331: , HPA047815: " "unprognostic (5.58e-3)" "unprognostic (1.26e-1)" "unprognostic (2.62e-1)" "unprognostic (3.53e-1)" "unprognostic (1.01e-1)" "unprognostic (1.34e-1)" "unprognostic (7.53e-3)" "unprognostic (7.48e-2)" "unprognostic (4.43e-1)" "validated prognostic favorable (3.17e-11)" "validated prognostic favorable (5.46e-5)" "unprognostic (2.41e-3)" "potential prognostic favorable (6.49e-4)" "unprognostic (3.33e-1)" "unprognostic (1.21e-1)" "unprognostic (9.96e-3)" "unprognostic (3.60e-3)" "unprognostic (6.92e-2)" "unprognostic (1.45e-2)" "unprognostic (1.38e-2)" "unprognostic (2.10e-2)" "unprognostic (1.07e-1)" "unprognostic (1.22e-2)" "unprognostic (8.70e-3)" "unprognostic (3.76e-2)" "potential prognostic unfavorable (9.17e-4)" "unprognostic (1.74e-1)" "unprognostic (1.53e-1)" "unprognostic (1.12e-1)" PLPP2 "LPP2, PAP-2c, PPAP2C" ENSG00000141934 "Phospholipid phosphatase 2" O43688 19 281040-291403 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 103.7" "Cell type enhanced" "Detected in many" "Breast lactating cells: 209.5;Breast secretory cells: 226.9;Cholangiocytes: 219.1;Enterocytes: 188.7;Fallopian tube ciliated cells: 299.2;Pancreatic duct cells: 187.3;Prostatic club cells: 175.2;Respiratory ciliated cells: 298.1;Respiratory secretory cells: 248.8;Submucosal glandular cells: 221.7" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 30.3;endothelial cell: 24.2;oligodendrocyte: 97.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 3.3;MAIT T-cell: 6.6" "Lineage enriched" "Detected in single" 40 "T-cells: 6.6" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Liver - Cholangiocytes, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Skin - Keratinocyte (other), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055540, HPA058428" Uncertain Supported "Plasma membrane" NA NA "Cluster 60: Stomach - Digestion" "Cluster 11: White matter - Signal transduction" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 6 "Plasma membrane" "HPA055540: , HPA058428: " "unprognostic (4.63e-2)" "potential prognostic unfavorable (5.64e-4)" "unprognostic (4.43e-2)" "unprognostic (4.18e-2)" "unprognostic (1.37e-1)" "unprognostic (2.19e-1)" "unprognostic (4.07e-3)" "unprognostic (2.59e-1)" "unprognostic (2.60e-2)" "unprognostic (4.40e-3)" "unprognostic (9.52e-3)" "unprognostic (6.69e-2)" "unprognostic (2.71e-3)" "unprognostic (2.92e-1)" "unprognostic (1.27e-2)" "unprognostic (1.72e-1)" "unprognostic (9.50e-2)" "unprognostic (1.55e-1)" "unprognostic (1.98e-2)" "potential prognostic unfavorable (6.14e-4)" "unprognostic (8.63e-2)" "unprognostic (2.86e-1)" "unprognostic (8.48e-2)" "unprognostic (8.31e-2)" "unprognostic (2.79e-1)" "unprognostic (1.02e-2)" "unprognostic (2.63e-1)" "unprognostic (3.93e-3)" "unprognostic (1.54e-3)" PLPP3 "LPP3, PAP-2b, PPAP2B" ENSG00000162407 "Phospholipid phosphatase 3" O14495 1 56494761-56645301 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 279.4;Bergmann glia: 304.5;Cardiomyocytes: 301.3;Endometrial stromal cells: 325.2;Fibro-adipogenic progenitors: 291.9;Fibroblasts: 291.8;Leydig cells: 598.7;Pericytes: 262.3;Salivary myoepithelial cells: 273.9;Vascular endothelial cells: 275.2;Vascular smooth muscle cells: 284.0" "Cell type enhanced" "Detected in all" "astrocyte: 313.9;Bergmann glia: 310.9" "Cancer enhanced" "Detected in all" "Thyroid Carcinoma (TCGA): 405.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 2.4;naive B-cell: 2.3" "Lineage enriched" "Detected in single" 6 "B-cells: 2.4" "Cancer enhanced" "Detected in many" "thyroid cancer: 65.5" "Kidney - Endothelial cells, Prostate - Fibroblasts, Skin - Fibroblasts_2, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072751 Approved Supported "Golgi apparatus,Mid piece,Principal piece" NA Yes "Cluster 23: B-cells - Immunoglobulins" "Cluster 75: Ovary - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 103: Non-specific - Basic cellular processes" 7 "Golgi apparatus" "Mid piece, Principal piece" "HPA072751: " "unprognostic (1.22e-2)" "unprognostic (8.74e-2)" "unprognostic (9.95e-2)" "unprognostic (1.81e-1)" "unprognostic (5.20e-3)" "unprognostic (1.46e-1)" "unprognostic (1.28e-2)" "unprognostic (2.81e-3)" "unprognostic (1.48e-1)" "validated prognostic favorable (3.94e-13)" "validated prognostic favorable (5.01e-7)" "unprognostic (3.43e-1)" "unprognostic (1.91e-2)" "unprognostic (8.13e-2)" "unprognostic (2.38e-2)" "unprognostic (1.29e-1)" "unprognostic (8.05e-2)" "unprognostic (2.24e-2)" "unprognostic (5.66e-3)" "unprognostic (5.63e-2)" "unprognostic (1.87e-2)" "unprognostic (2.20e-1)" "unprognostic (1.26e-2)" "unprognostic (3.84e-2)" "unprognostic (1.58e-1)" "unprognostic (1.40e-2)" "unprognostic (1.55e-1)" "unprognostic (7.51e-2)" "unprognostic (3.93e-1)" PLPP4 "DPPL2, PPAPDC1, PPAPDC1A" ENSG00000203805 "Phospholipid phosphatase 4" Q5VZY2 10 120457227-120592065 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 2.0" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 60.1;Erythrocyte progenitors: 62.9;Leydig cells: 66.3;Oligodendrocyte progenitor cells: 322.1;Oligodendrocytes: 49.0;Other brain neurons: 55.2;Renal collecting duct intercalated cells: 118.5;Renal connecting tubule cells: 157.1;Sertoli cells: 41.8" "Cell type enhanced" "Detected in many" "oligodendrocyte precursor cell: 393.3;upper rhombic lip: 170.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells, Liver - Hepatic stellate cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045188 Approved Approved "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 49: Hindbrain - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 29 "Nucleoli, Nucleoli rim" Nucleoplasm "HPA045188: " "unprognostic (6.25e-2)" "unprognostic (3.31e-1)" "potential prognostic favorable (7.89e-4)" "unprognostic (1.07e-2)" "unprognostic (3.96e-3)" "unprognostic (1.62e-2)" "potential prognostic favorable (7.65e-4)" PLPP5 "DPPL1, HTPAP, PPAPDC1B" ENSG00000147535 "Phospholipid phosphatase 5" Q8NEB5 8 38263130-38269243 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 232.3;Gastric chief cells: 180.2;Plasma cells: 303.7;Prostatic glandular cells: 168.9" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 82.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 8 "basophil: 80.7;memory B-cell: 212.7;naive B-cell: 307.0" "Group enriched" "Detected in all" 7 "B-cells: 307.0;granulocytes: 80.7" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Stomach - Chief cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055777 Approved Vesicles NA NA "Cluster 32: Basophils - Transcription" "Cluster 8: Pancreas - Proteolysis" "Cluster 23: Choroid plexus - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 1 Vesicles "HPA055777: " "unprognostic (2.57e-2)" "unprognostic (2.06e-3)" "unprognostic (1.56e-1)" "unprognostic (4.84e-1)" "unprognostic (2.77e-2)" "potential prognostic unfavorable (1.83e-4)" "unprognostic (8.44e-2)" "unprognostic (2.84e-2)" "unprognostic (1.45e-1)" "unprognostic (2.13e-2)" "unprognostic (1.24e-2)" "potential prognostic unfavorable (3.26e-4)" "unprognostic (1.98e-2)" "unprognostic (1.85e-1)" "unprognostic (6.70e-2)" "unprognostic (1.29e-2)" "unprognostic (5.59e-3)" "unprognostic (1.29e-2)" "unprognostic (1.93e-1)" "unprognostic (7.05e-2)" "unprognostic (2.72e-2)" "unprognostic (4.19e-2)" "unprognostic (1.43e-1)" "unprognostic (1.85e-1)" "unprognostic (1.04e-1)" "unprognostic (2.50e-1)" "unprognostic (1.47e-1)" "unprognostic (2.19e-2)" "unprognostic (2.46e-1)" PLPP6 "FLJ46512, FLJ90191, PDP1, PPAPDC2" ENSG00000205808 "Phospholipid phosphatase 6" Q8IY26 9 4662294-4665258 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Immunity, Innate immunity, Lipid metabolism" "Hydrolase, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 24.1;Early spermatids: 110.2;Late spermatids: 63.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Spleen - B-cells (Spleen), Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018096 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 70: Non-specific - Protein processing" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 46 "Nucleoplasm, Vesicles" Cytosol "HPA018096: " "unprognostic (1.09e-2)" "unprognostic (4.32e-2)" "unprognostic (1.32e-1)" "unprognostic (2.61e-1)" "unprognostic (1.14e-1)" "unprognostic (2.06e-1)" "unprognostic (1.43e-1)" "unprognostic (1.50e-2)" "unprognostic (2.41e-1)" "potential prognostic favorable (2.05e-4)" "unprognostic (1.54e-1)" "unprognostic (9.08e-2)" "unprognostic (3.40e-2)" "unprognostic (9.26e-2)" "unprognostic (1.07e-1)" "unprognostic (9.07e-2)" "unprognostic (4.11e-2)" "unprognostic (7.33e-2)" "unprognostic (2.61e-1)" "unprognostic (1.76e-1)" "unprognostic (1.62e-1)" "unprognostic (1.06e-1)" "unprognostic (4.02e-2)" "unprognostic (1.15e-1)" "unprognostic (5.78e-3)" "unprognostic (3.03e-1)" "unprognostic (1.09e-1)" "unprognostic (5.99e-2)" "unprognostic (5.48e-2)" PLPP7 "C9orf67, FLJ14662, MGC12921, NET39, PPAPDC3" ENSG00000160539 "Phospholipid phosphatase 7 (inactive)" Q8NBV4 9 131289459-131359022 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "heart muscle: 87.4;skeletal muscle: 196.8;tongue: 69.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 84.4;Extravillous trophoblasts: 67.3;Myonuclei: 282.1;Oocytes: 69.1;Retinal amacrine cells: 107.4;Retinal bipolar cells: 222.8;Retinal ganglion cells: 38.6" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 10.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Neuroblastoma: 5.9;Rhabdoid: 5.8" "Heart muscle - Cardiomyocytes, Kidney - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070252 Uncertain Uncertain Nucleoplasm,Vesicles No No "Cluster 2: Dendritic cells - Unknown function" "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 37: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" "Nucleoplasm, Vesicles" "HPA070252: " "unprognostic (6.60e-2)" "unprognostic (2.11e-1)" "unprognostic (1.18e-1)" "unprognostic (1.62e-1)" "unprognostic (3.08e-1)" "unprognostic (1.13e-1)" "unprognostic (1.14e-1)" "unprognostic (6.16e-3)" "unprognostic (5.26e-2)" "potential prognostic favorable (5.00e-4)" "unprognostic (8.72e-3)" "unprognostic (6.61e-2)" "unprognostic (1.55e-2)" "unprognostic (3.63e-2)" "unprognostic (1.16e-1)" "unprognostic (2.65e-2)" "unprognostic (4.20e-2)" PLPPR1 "FLJ20300, LPPR1, MGC26189, PRG-3" ENSG00000148123 "Phospholipid phosphatase related 1" Q8TBJ4 9 101028727-101325135 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 24.7;kidney: 14.6" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 78.6;Brain inhibitory neurons: 291.4;Distal convoluted tubule cells: 344.5;Loop of henle epithelial cells: 96.4;Oligodendrocyte progenitor cells: 804.1;Oligodendrocytes: 553.6;Other brain neurons: 73.6;Proximal tubule cells: 157.9;Renal collecting duct intercalated cells: 101.0" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 1085.9;oligodendrocyte precursor cell: 885.3" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 16.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lung cancer: 1.1" "Liver - Hepatocytes, Pancreas - Alpha cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA014760, HPA014968, HPA014979" Supported Supported Nucleoplasm NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 14 Nucleoplasm "HPA014760: , HPA014968: , HPA014979: " "unprognostic (2.02e-1)" "unprognostic (1.05e-3)" "unprognostic (2.73e-1)" "unprognostic (2.26e-2)" "unprognostic (3.06e-1)" "unprognostic (1.21e-3)" "unprognostic (1.83e-2)" "unprognostic (6.90e-2)" "unprognostic (3.21e-2)" "unprognostic (2.47e-1)" "unprognostic (2.62e-1)" PLPPR2 "LPPR2, PRG-4" ENSG00000105520 "Phospholipid phosphatase related 2" Q96GM1 19 11355386-11365698 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 86.0" "Cell type enhanced" "Detected in many" "Neutrophils: 85.7;Other brain neurons: 38.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 71.5" "Lineage enriched" "Detected in many" 4 "granulocytes: 71.5" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Liver - Vascular endothelial cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048973, HPA077966" Approved Uncertain Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 78: Brain - Neuronal signaling" "Cluster 29: Forebrain - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 33 Nucleoplasm "HPA048973: , HPA077966: " "unprognostic (2.14e-3)" "unprognostic (1.31e-1)" "unprognostic (1.09e-1)" "unprognostic (3.72e-3)" "unprognostic (2.51e-1)" "unprognostic (1.51e-1)" "unprognostic (8.64e-2)" "unprognostic (4.31e-2)" "potential prognostic unfavorable (2.92e-6)" "unprognostic (4.37e-3)" "unprognostic (2.57e-3)" "unprognostic (1.93e-1)" "unprognostic (2.18e-2)" "unprognostic (7.87e-2)" "unprognostic (1.37e-1)" "unprognostic (1.07e-1)" "unprognostic (2.92e-1)" "unprognostic (2.41e-1)" "unprognostic (7.75e-2)" "unprognostic (6.90e-3)" "unprognostic (3.18e-1)" "unprognostic (1.20e-1)" "unprognostic (8.45e-2)" "unprognostic (1.36e-1)" "unprognostic (1.81e-1)" "unprognostic (1.69e-2)" "unprognostic (7.52e-2)" "unprognostic (2.00e-2)" "unprognostic (1.47e-1)" PLPPR3 "FLJ11535, LPPR3, PRG-2, PRG2" ENSG00000129951 "Phospholipid phosphatase related 3" Q6T4P5 19 812488-821955 "Metabolic proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 40.2" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 21.7;Endometrial ciliated cells: 37.3;Epicardial cells: 18.2;Fallopian tube ciliated cells: 112.0;Monocyte progenitors: 24.3;Neutrophil progenitors: 19.9;Other brain neurons: 33.0;Respiratory ciliated cells: 103.9" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Breast Invasive Carcinoma (TCGA): 7.7;Glioblastoma Multiforme (TCGA): 3.5;Testicular Germ Cell Tumor (TCGA): 11.6;Uterine Corpus Endometrial Carcinoma (TCGA): 4.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Leukemia: 29.8;Neuroblastoma: 20.8" "Breast - Breast glandular cells, Colon - Colon enteroendocrine cells, Lung - Respiratory ciliated cells, Spleen - Neutrophils_1, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052293, HPA057034" Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 107: Ciliated cells - Cilia assembly & function" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA052293: , HPA057034: " "unprognostic (1.75e-1)" "unprognostic (3.94e-2)" "unprognostic (3.09e-2)" "unprognostic (1.33e-1)" "unprognostic (1.46e-3)" "unprognostic (1.09e-1)" "unprognostic (6.54e-2)" PLPPR4 "KIAA0455, LPPR4, PHP1, PRG-1" ENSG00000117600 "Phospholipid phosphatase related 4" Q7Z2D5 1 99264292-99309590 "Metabolic proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 50.1" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 175.8;Brain inhibitory neurons: 199.1;Corticotrophs: 147.5;Lactotrophs: 188.1;Melanocytes: 182.1;Oligodendrocyte progenitor cells: 131.3;Other brain neurons: 153.8;Pituicytes/FSCs: 99.7;Retinal horizontal cells: 62.1;Somatotrophs: 97.3;Thyrotrophs: 198.2" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 7.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Brain cancer: 6.8;Neuroblastoma: 19.7" "Breast - Endothelial cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 35: Neurons - Synaptic function & neurogenesis" 1 "unprognostic (1.52e-1)" "unprognostic (1.09e-2)" "unprognostic (1.42e-1)" "unprognostic (1.58e-2)" "potential prognostic unfavorable (6.71e-5)" "unprognostic (1.99e-1)" "unprognostic (3.94e-1)" "unprognostic (3.27e-1)" "potential prognostic unfavorable (2.09e-4)" PLPPR5 "LPPR5, PAP2, PAP2D, PRG5" ENSG00000117598 "Phospholipid phosphatase related 5" Q32ZL2 1 98890245-99227929 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.5;retina: 1.5;testis: 1.9" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 79.2;Brain inhibitory neurons: 114.0;Lactotrophs: 137.2;Oligodendrocyte progenitor cells: 191.4;Other brain neurons: 62.0;Retinal amacrine cells: 147.6;Thyrotrophs: 252.5" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in some" 11 "Glioblastoma Multiforme (TCGA): 5.1;Kidney Renal Clear Cell Carcinoma (TCGA): 2.7;Kidney Renal Papillary Cell Carcinoma (TCGA): 2.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Neuroblastoma: 12.2" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pituitary gland - Thyrotropes, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018072, HPA059085" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 29: Forebrain - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" "Plasma membrane" Cytosol "HPA018072: , HPA059085: " "unprognostic (4.61e-1)" "unprognostic (6.26e-2)" "unprognostic (8.41e-3)" "unprognostic (1.91e-1)" "unprognostic (3.17e-3)" PLRG1 "Cwc1, PRL1, Prp46, PRPF46, TANGO4" ENSG00000171566 "Pleiotropic regulator 1" O43660 4 154535005-154550400 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "HPA035931, HPA035932, HPA061486" Supported Supported "Nucleoplasm,Nuclear membrane,Nucleoli fibrillar center,Nuclear speckles" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 13: Non-specific - Mixed function" "Cluster 17: Non-specific - RNA processing" 65 "Nucleoplasm, Nuclear speckles" "Nuclear membrane, Nucleoli fibrillar center" "HPA035931: , HPA035932: , HPA061486: " "unprognostic (1.12e-1)" "unprognostic (2.37e-2)" "unprognostic (5.88e-2)" "unprognostic (6.26e-2)" "unprognostic (4.56e-3)" "unprognostic (1.09e-1)" "unprognostic (1.24e-1)" "unprognostic (4.26e-2)" "unprognostic (2.04e-2)" "potential prognostic unfavorable (8.45e-4)" "validated prognostic favorable (1.83e-11)" "validated prognostic favorable (1.62e-4)" "unprognostic (2.39e-1)" "unprognostic (1.83e-3)" "unprognostic (2.54e-1)" "unprognostic (1.51e-2)" "unprognostic (3.96e-3)" "unprognostic (4.84e-1)" "unprognostic (8.51e-2)" "unprognostic (2.06e-2)" "unprognostic (3.67e-3)" "unprognostic (3.58e-3)" "unprognostic (1.29e-2)" "unprognostic (1.19e-2)" "unprognostic (2.39e-2)" "potential prognostic favorable (1.00e-4)" "unprognostic (2.44e-2)" "unprognostic (5.54e-2)" "unprognostic (1.34e-1)" "unprognostic (1.39e-1)" "unprognostic (3.29e-2)" PLS1 ENSG00000120756 "Plastin 1" Q14651 3 142596393-142713664 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "intestine: 296.8" "Cell type enhanced" "Detected in many" "Colonocytes: 477.2;Enterocytes: 613.3;Foveolar cells: 260.6;Goblet cells: 291.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "granulocytes: 2.6;NK-cells: 3.0;T-cells: 2.5" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Liver - Hepatocytes, Lung - Alveolar cells type 2, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000895, HPA055744, HPA061936" Enhanced Approved "Plasma membrane" NA NA 28000000 "Cluster 35: Neutrophils - Protein binding" "Cluster 77: Intestine - Digestion" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 9 "Plasma membrane" "HPA000895: , HPA055744: , HPA061936: " "potential prognostic favorable (1.27e-4)" "unprognostic (6.99e-2)" "unprognostic (3.39e-1)" "unprognostic (1.30e-1)" "unprognostic (2.75e-2)" "unprognostic (1.90e-1)" "unprognostic (1.27e-1)" "unprognostic (1.84e-3)" "unprognostic (2.54e-2)" "unprognostic (8.22e-2)" "potential prognostic favorable (8.51e-12)" "unprognostic (2.13e-3)" "unprognostic (1.44e-2)" "unprognostic (1.38e-1)" "unprognostic (6.11e-2)" "unprognostic (1.10e-3)" "unprognostic (1.87e-2)" "unprognostic (1.62e-1)" "unprognostic (2.50e-1)" "unprognostic (3.36e-1)" "unprognostic (6.94e-2)" "potential prognostic unfavorable (6.69e-4)" "unprognostic (1.82e-3)" "unprognostic (4.05e-2)" "unprognostic (1.75e-2)" "unprognostic (1.23e-1)" "unprognostic (2.38e-1)" "unprognostic (3.28e-2)" "unprognostic (1.40e-1)" "unprognostic (3.47e-2)" "unprognostic (1.67e-1)" PLS3 T-plastin ENSG00000102024 "Plastin 3" P13797 X 115561174-115650861 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Disease variant, Osteoporosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 451.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 502.2;Esophageal apical cells: 826.7;Esophageal suprabasal cells: 316.3;Ocular epithelial cells: 414.1;Suprabasal keratinocytes: 344.1;Urothelial cells: 349.1;Vascular smooth muscle cells: 368.9" "Cell type enhanced" "Detected in many" "vascular associated smooth muscle cell: 445.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "NK-cell: 3.8;plasmacytoid DC: 12.2" "Group enriched" "Detected in many" 5 "dendritic cells: 12.2;NK-cells: 3.8" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Kidney - Fibroblasts, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000895, HPA020433, HPA076083" Approved Approved "Plasma membrane,Cytosol" NA NA 88000000 "Cluster 13: Non-specific - Mitochondria" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 19 "Plasma membrane, Cytosol" "HPA000895: , HPA020433: , HPA076083: " "unprognostic (2.96e-3)" "unprognostic (2.94e-2)" "unprognostic (2.32e-1)" "unprognostic (1.31e-3)" "unprognostic (3.81e-1)" "unprognostic (2.41e-2)" "unprognostic (7.78e-2)" "unprognostic (2.42e-3)" "potential prognostic unfavorable (4.21e-4)" "unprognostic (5.86e-3)" "unprognostic (3.85e-3)" "unprognostic (1.92e-1)" "potential prognostic unfavorable (4.11e-5)" "unprognostic (4.00e-1)" "unprognostic (1.13e-1)" "unprognostic (1.45e-1)" "potential prognostic unfavorable (3.70e-4)" "unprognostic (2.65e-1)" "unprognostic (3.73e-2)" "unprognostic (1.95e-1)" "unprognostic (8.66e-2)" "unprognostic (4.77e-3)" "unprognostic (9.43e-2)" "unprognostic (1.32e-1)" "unprognostic (8.52e-2)" "unprognostic (1.65e-1)" "unprognostic (1.68e-1)" "unprognostic (1.63e-2)" "unprognostic (1.95e-1)" "unprognostic (1.31e-1)" "unprognostic (2.08e-1)" PLSCR1 MMTRA1B ENSG00000188313 "Phospholipid scramblase 1" O15162 3 146515180-146544856 "Predicted intracellular proteins, Transporters" "Antiviral defense, Host-virus interaction, Lipid transport, Transport" "DNA-binding, Host cell receptor for virus entry, Hydrolase, Nuclease, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 626.4;monocytes: 403.3;Neutrophil progenitors: 470.1;Neutrophils: 830.3" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 138.4;endothelial cell: 201.9;pericyte: 148.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells, Kidney - Endothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA068923, CAB070421" Approved Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" NA Yes 47000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 81 "Nucleoplasm, Golgi apparatus, Plasma membrane" "CAB070421: , HPA068923: " "unprognostic (8.19e-2)" "unprognostic (1.57e-1)" "unprognostic (4.39e-1)" "unprognostic (7.66e-2)" "unprognostic (1.23e-1)" "unprognostic (1.03e-1)" "unprognostic (1.00e-1)" "unprognostic (4.68e-3)" "unprognostic (2.75e-1)" "unprognostic (2.97e-2)" "potential prognostic favorable (7.04e-6)" "unprognostic (2.53e-2)" "unprognostic (2.14e-1)" "unprognostic (5.61e-2)" "unprognostic (2.99e-2)" "potential prognostic unfavorable (2.96e-4)" "unprognostic (5.24e-3)" "unprognostic (1.04e-1)" "unprognostic (4.32e-2)" "unprognostic (1.15e-1)" "unprognostic (1.50e-1)" "unprognostic (4.65e-3)" "unprognostic (1.43e-2)" "unprognostic (1.95e-1)" "unprognostic (5.68e-2)" "unprognostic (1.58e-1)" "unprognostic (1.03e-1)" "unprognostic (2.01e-1)" "unprognostic (2.15e-2)" "unprognostic (1.68e-1)" "unprognostic (2.86e-2)" PLSCR2 ENSG00000163746 "Phospholipid scramblase 2" Q9NRY7 3 146391421-146495991 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "testis: 12.7" "Group enriched" "Detected in many" 6 "Early spermatids: 300.2;Late primary spermatocytes: 120.8;Late spermatids: 437.5" "Cell type enhanced" "Detected in many" "midbrain-derived inhibitory: 5.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" HPA051352 Supported "Nucleoplasm,Endoplasmic reticulum,Vesicles" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 44: Non-specific - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 11 Nucleoplasm "Endoplasmic reticulum, Vesicles" "HPA051352: " "unprognostic (8.52e-2)" "unprognostic (2.12e-2)" PLSCR3 ENSG00000187838 "Phospholipid scramblase 3" Q9NRY6 17 7389727-7394842 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Astrocytes: 6.5;Bergmann glia: 5.6;Brain excitatory neurons: 4.8;Brain inhibitory neurons: 5.2;Choroid plexus epithelial cells: 2.2;Ependymal cells: 3.0;Microglia: 2.1;Oligodendrocyte progenitor cells: 4.6;Oligodendrocytes: 4.0;Other brain neurons: 5.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Liver - Vascular endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048387, HPA068609" Supported Supported Mitochondria NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 74: Non-specific - Signal transduction" "Cluster 44: Non-specific - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 22: Non-specific - Basic cellular functions" 28 Mitochondria "HPA048387: , HPA068609: " "unprognostic (6.93e-2)" "unprognostic (1.47e-2)" "unprognostic (5.54e-2)" "unprognostic (7.09e-3)" "unprognostic (5.04e-2)" "unprognostic (2.12e-1)" "unprognostic (6.02e-3)" "unprognostic (1.35e-3)" "unprognostic (4.73e-2)" "unprognostic (9.06e-2)" "potential prognostic favorable (6.95e-4)" "unprognostic (4.00e-2)" "unprognostic (8.96e-2)" "unprognostic (2.52e-1)" "unprognostic (5.17e-3)" "unprognostic (2.67e-3)" "unprognostic (1.10e-1)" "unprognostic (6.43e-2)" "unprognostic (3.33e-2)" "unprognostic (2.54e-2)" "unprognostic (2.83e-2)" "unprognostic (4.72e-1)" "unprognostic (1.51e-2)" "unprognostic (1.97e-2)" "unprognostic (2.05e-1)" "unprognostic (1.35e-1)" "unprognostic (1.28e-1)" "unprognostic (4.56e-2)" "unprognostic (5.27e-2)" "unprognostic (5.72e-2)" "unprognostic (1.23e-2)" PLSCR4 ENSG00000114698 "Phospholipid scramblase 4" Q9NRQ2 3 146192335-146251179 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 197.0;Bergmann glia: 306.1;Fibro-adipogenic progenitors: 303.4;Lymphatic endothelial cells: 462.1;Mesothelial cells: 202.4;Schwann cells: 192.5;Sertoli cells: 267.2;Vascular endothelial cells: 219.9" "Group enriched" "Detected in many" 6 "astrocyte: 239.6;Bergmann glia: 330.9;endothelial cell: 155.0;ependymal cell: 127.0;fibroblast: 170.5;oligodendrocyte precursor cell: 93.8;pericyte: 169.2;vascular associated smooth muscle cell: 102.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells, Heart muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002276 Uncertain Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 39: Astrocytes - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 49 "Nucleoplasm, Nuclear bodies" "HPA002276: " "unprognostic (2.72e-2)" "unprognostic (2.47e-2)" "unprognostic (2.20e-3)" "unprognostic (1.59e-1)" "unprognostic (2.54e-1)" "unprognostic (2.64e-3)" "unprognostic (2.93e-1)" "unprognostic (2.65e-2)" "unprognostic (2.76e-3)" "unprognostic (6.39e-2)" "validated prognostic favorable (3.14e-6)" "validated prognostic favorable (3.13e-6)" "unprognostic (1.59e-1)" "unprognostic (2.96e-2)" "unprognostic (1.72e-2)" "unprognostic (2.17e-1)" "unprognostic (1.75e-1)" "unprognostic (1.13e-2)" "unprognostic (1.82e-2)" "unprognostic (8.61e-2)" "unprognostic (1.69e-2)" "unprognostic (2.80e-1)" "unprognostic (2.84e-1)" "unprognostic (2.29e-1)" "unprognostic (1.00e-1)" "unprognostic (1.82e-1)" "unprognostic (6.89e-3)" "unprognostic (1.54e-2)" "unprognostic (1.89e-1)" "unprognostic (1.91e-2)" "unprognostic (1.88e-1)" PLSCR5 ENSG00000231213 "Phospholipid scramblase family member 5" A0PG75 3 146576555-146605346 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Brain inhibitory neurons: 1.8;Cone photoreceptor cells: 2.1;Foveolar cells: 1.5;Gonadotrophs: 2.7;Late primary spermatocytes: 1.0" "Group enriched" "Detected in some" 5 "CGE interneuron: 4.4;splatter: 3.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 5.5;testis cancer: 1.5" "Region enhanced" "Detected in single" "midbrain: 1.0" "Low region specificity" "Detected in many" HPA047249 Uncertain NA NA "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 50: Lymphoma - Unknown function" "Cluster 109: Neurons - Neuronal signaling" "HPA047249: " PLTP BPIFE ENSG00000100979 "Phospholipid transfer protein" P55058 20 45898621-45912155 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Hofbauer cells: 3538.9" "Cell type enhanced" "Detected in many" "ependymal cell: 336.0;fibroblast: 119.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 33.2;eosinophil: 29.6" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Rhabdoid: 187.5" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Kidney - Macrophages, Lung - Fibroblasts_2, Minor Salivary Gland - Macrophages, Prostate - Fibroblasts, Skeletal muscle - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB032873 Approved "Secreted to blood" Transport NA NA 9720000000 650000000 "Cluster 41: Basophils - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 3: Choroid plexus - Cilium" "Cluster 5: Rhabdoid - Unknown function" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 2 "CAB032873: " "unprognostic (1.70e-1)" "unprognostic (3.19e-1)" "unprognostic (1.12e-1)" "unprognostic (3.65e-2)" "unprognostic (1.82e-2)" "unprognostic (1.44e-1)" "unprognostic (5.34e-3)" "potential prognostic unfavorable (3.67e-4)" "unprognostic (8.32e-2)" "unprognostic (3.59e-2)" "validated prognostic unfavorable (3.07e-8)" "validated prognostic unfavorable (3.18e-6)" "unprognostic (9.34e-2)" "unprognostic (2.38e-2)" "unprognostic (5.23e-2)" "unprognostic (3.37e-2)" "unprognostic (8.99e-2)" "unprognostic (6.40e-3)" "unprognostic (1.08e-1)" "unprognostic (2.01e-2)" "unprognostic (1.93e-2)" "unprognostic (1.04e-1)" "unprognostic (5.18e-1)" "unprognostic (2.49e-1)" "unprognostic (1.10e-1)" "unprognostic (1.09e-3)" "unprognostic (2.09e-1)" "potential prognostic unfavorable (5.06e-4)" "unprognostic (1.74e-1)" "unprognostic (1.07e-1)" "unprognostic (2.76e-1)" PLVAP "FELS, gp68, PV-1, PV1" ENSG00000130300 "Plasmalemma vesicle associated protein" Q9BX97 19 17351450-17377342 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 419.4" "Cell type enriched" "Detected in many" 15 "Vascular endothelial cells: 583.5" "Group enriched" "Detected in some" 11 "central nervous system macrophage: 36.8;endothelial cell: 18.5" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 563.1" "Region enriched" "Detected in all" 7 "choroid plexus: 35.1" "Immune cell enriched" "Detected in some" 6 "plasmacytoid DC: 35.2" "Lineage enriched" "Detected in many" 6 "dendritic cells: 35.2" "Group enriched" "Detected in some" 15 "Leukemia: 10.7;lymphoma: 3.9;ovarian cancer: 6.0" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Pituitary gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells, Thyroid gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002279 Supported Approved "Plasma membrane,Centrosome,Cytosol" NA NA 41000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 36: Choroid plexus - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" Cytosol "Plasma membrane, Centrosome" "HPA002279: " "unprognostic (2.96e-1)" "unprognostic (3.26e-1)" "unprognostic (1.54e-2)" "unprognostic (2.33e-1)" "unprognostic (1.15e-1)" "unprognostic (8.98e-2)" "unprognostic (4.84e-2)" "unprognostic (1.09e-1)" "potential prognostic favorable (7.04e-4)" "unprognostic (6.44e-2)" "validated prognostic favorable (1.05e-7)" "validated prognostic favorable (1.84e-5)" "unprognostic (1.63e-2)" "unprognostic (2.07e-2)" "unprognostic (1.94e-2)" "unprognostic (6.69e-3)" "unprognostic (1.32e-2)" "unprognostic (8.98e-3)" "unprognostic (2.17e-1)" "unprognostic (1.97e-1)" "unprognostic (1.11e-2)" "unprognostic (1.21e-2)" "unprognostic (1.70e-1)" "unprognostic (4.22e-2)" "unprognostic (1.13e-1)" "unprognostic (4.11e-1)" "unprognostic (4.18e-2)" "unprognostic (1.02e-2)" "unprognostic (1.28e-1)" "unprognostic (2.59e-1)" "unprognostic (5.66e-2)" PLXDC1 "TEM3, TEM7" ENSG00000161381 "Plexin domain containing 1" Q8IUK5 17 39063313-39154394 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 44.9" "Cell type enriched" "Detected in many" 4 "Retinal bipolar cells: 488.5" "Cell type enriched" "Detected in all" 5 "pericyte: 696.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in some" 5 "Rhabdoid: 13.9" "Adipose subcutaneous - Adipose progenitor cells, Kidney - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA012805 Approved "Intracellular and membrane" "No annotated function" NA NA 3100000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 37: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "HPA012805: " "unprognostic (5.73e-2)" "unprognostic (3.90e-2)" "unprognostic (4.41e-2)" "unprognostic (2.66e-1)" "unprognostic (3.71e-2)" "unprognostic (2.37e-1)" "unprognostic (1.41e-1)" "unprognostic (9.02e-2)" "unprognostic (9.62e-2)" "unprognostic (4.95e-2)" "unprognostic (5.49e-2)" "unprognostic (1.17e-2)" "potential prognostic unfavorable (6.94e-4)" "unprognostic (2.45e-2)" "unprognostic (2.42e-1)" "unprognostic (3.57e-1)" "unprognostic (5.40e-3)" "unprognostic (1.09e-1)" "unprognostic (9.07e-2)" "unprognostic (5.92e-2)" "unprognostic (2.30e-3)" "unprognostic (6.55e-2)" "unprognostic (1.35e-1)" "unprognostic (9.51e-2)" "unprognostic (3.66e-1)" "potential prognostic favorable (6.49e-4)" "unprognostic (1.55e-2)" "unprognostic (1.80e-3)" "unprognostic (5.90e-2)" "unprognostic (1.05e-1)" "unprognostic (6.43e-2)" PLXDC2 "FLJ14623, TEM7R" ENSG00000120594 "Plexin domain containing 2" Q6UX71 10 19816239-20289856 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Fibro-adipogenic progenitors: 1608.6;Macrophages: 1941.1;Megakaryocyte progenitors: 1608.3;Microglia: 7582.4;monocytes: 1654.0;Neutrophils: 2495.4" "Group enriched" "Detected in all" 6 "central nervous system macrophage: 9410.5;mammillary body: 2635.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 57.6;intermediate monocyte: 33.4;myeloid DC: 36.1;neutrophil: 81.8;non-classical monocyte: 37.5" "Group enriched" "Detected in many" 13 "dendritic cells: 36.1;granulocytes: 81.8;monocytes: 57.6" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Kidney - Fibroblasts, Lung - Fibroblasts_1, Prostate - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017268, HPA070793" Approved Supported "Nuclear bodies" No No 85000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 72: Neuronal - Signal transduction" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 2 "Nuclear bodies" "HPA017268: , HPA070793: " "unprognostic (6.21e-2)" "unprognostic (1.39e-1)" "unprognostic (4.54e-1)" "unprognostic (1.76e-2)" "unprognostic (1.87e-2)" "potential prognostic unfavorable (7.36e-4)" "unprognostic (6.50e-2)" "unprognostic (1.39e-1)" "unprognostic (9.05e-2)" "unprognostic (1.17e-1)" "potential prognostic favorable (1.91e-7)" "unprognostic (1.88e-1)" "unprognostic (3.06e-1)" "unprognostic (1.88e-2)" "unprognostic (5.16e-2)" "unprognostic (3.32e-2)" "unprognostic (2.81e-2)" "unprognostic (2.01e-2)" "unprognostic (9.65e-2)" "unprognostic (5.57e-3)" "unprognostic (4.65e-3)" "unprognostic (1.36e-1)" "unprognostic (3.65e-2)" "unprognostic (1.38e-1)" "unprognostic (3.87e-2)" "unprognostic (5.97e-2)" "unprognostic (2.02e-2)" "unprognostic (3.19e-3)" "unprognostic (6.35e-2)" "unprognostic (6.87e-2)" "unprognostic (3.15e-1)" PLXNA1 "NOV, PLXN1" ENSG00000114554 "Plexin A1" Q9UIW2 3 126982693-127037389 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 5 "Alveolar cells type 1: 165.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007499, CAB012483" Uncertain Approved "Nucleoplasm,Centrosome,Basal body,Cytosol" NA NA 22000000 "Cluster 24: Non-specific - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 81: Alveolar cells - Lung function" 42 "Nucleoplasm, Cytosol" "Centrosome, Basal body" "CAB012483: , HPA007499: " "unprognostic (2.12e-1)" "unprognostic (2.13e-1)" "unprognostic (2.44e-2)" "unprognostic (2.67e-2)" "unprognostic (1.62e-1)" "unprognostic (2.00e-1)" "unprognostic (9.97e-2)" "unprognostic (3.57e-1)" "unprognostic (9.32e-3)" "unprognostic (3.71e-2)" "unprognostic (3.11e-2)" "unprognostic (1.11e-3)" "unprognostic (1.47e-1)" "potential prognostic unfavorable (1.92e-5)" "unprognostic (8.81e-2)" "unprognostic (1.28e-1)" "unprognostic (1.21e-1)" "unprognostic (1.32e-1)" "unprognostic (6.41e-2)" "potential prognostic unfavorable (6.12e-4)" "unprognostic (2.71e-1)" "unprognostic (3.41e-3)" "potential prognostic unfavorable (4.38e-4)" "unprognostic (1.05e-1)" "unprognostic (7.57e-2)" "unprognostic (1.93e-2)" "unprognostic (1.39e-1)" "unprognostic (2.34e-2)" "unprognostic (1.39e-1)" "unprognostic (1.26e-3)" "unprognostic (1.17e-2)" PLXNA2 "FLJ11751, FLJ30634, KIAA0463, OCT, PLXN2" ENSG00000076356 "Plexin A2" O75051 1 208022242-208244384 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 33.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 339.8;Choroid plexus epithelial cells: 595.2;Pancreatic acinar cells: 287.0;Retinal amacrine cells: 284.7;Retinal horizontal cells: 569.0;Vascular endothelial cells: 252.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells, Heart muscle - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Minor salivary gland basal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB009763 Approved NA NA 420000 "Cluster 70: Non-specific - Protein processing" "Cluster 23: Choroid plexus - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 2 "CAB009763: " "unprognostic (6.32e-3)" "unprognostic (6.66e-2)" "unprognostic (9.72e-2)" "unprognostic (1.91e-2)" "unprognostic (5.81e-2)" "unprognostic (7.44e-2)" "unprognostic (2.65e-1)" "unprognostic (9.97e-2)" "unprognostic (1.36e-1)" "unprognostic (3.77e-2)" "potential prognostic favorable (7.80e-8)" "unprognostic (2.45e-3)" "unprognostic (2.60e-1)" "unprognostic (3.64e-3)" "unprognostic (2.10e-1)" "unprognostic (2.13e-2)" "unprognostic (2.74e-2)" "unprognostic (7.33e-2)" "unprognostic (2.47e-2)" "unprognostic (3.20e-2)" "unprognostic (2.06e-3)" "unprognostic (5.06e-1)" "unprognostic (1.01e-1)" "unprognostic (2.22e-1)" "unprognostic (1.41e-1)" "unprognostic (3.20e-1)" "unprognostic (7.26e-2)" "unprognostic (1.56e-1)" "unprognostic (1.12e-1)" "unprognostic (3.90e-2)" "unprognostic (1.84e-1)" PLXNA3 "6.3, Plxn3, PLXN4, SEX, XAP-6" ENSG00000130827 "Plexin A3" P51805 X 154458281-154477779 "Plasma proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000915 Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA 48000 "Cluster 64: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 109: Neurons - Neuronal signaling" 26 "Golgi apparatus, Cytosol" "Plasma membrane" "HPA000915: " "unprognostic (4.44e-2)" "unprognostic (3.20e-3)" "unprognostic (2.50e-2)" "unprognostic (5.04e-2)" "unprognostic (1.85e-2)" "unprognostic (4.93e-2)" "unprognostic (1.80e-1)" "unprognostic (3.02e-1)" "unprognostic (4.34e-2)" "unprognostic (6.55e-2)" "unprognostic (3.71e-2)" "unprognostic (4.33e-2)" "unprognostic (1.53e-1)" "unprognostic (1.07e-2)" "unprognostic (1.58e-1)" "unprognostic (5.77e-2)" "unprognostic (5.72e-3)" "unprognostic (7.24e-2)" "unprognostic (2.12e-1)" "unprognostic (2.83e-2)" "unprognostic (4.94e-3)" "unprognostic (1.49e-1)" "potential prognostic unfavorable (1.77e-4)" "unprognostic (1.15e-1)" "unprognostic (2.53e-1)" "unprognostic (1.38e-2)" "unprognostic (2.44e-1)" "unprognostic (3.66e-1)" "unprognostic (1.60e-1)" "unprognostic (1.09e-1)" "unprognostic (1.82e-2)" PLXNA4 "DKFZp434G0625PRO34003, FAYV2820, KIAA1550, PLXNA4A, PLXNA4B" ENSG00000221866 "Plexin A4" Q9HCM2 7 132123340-132648688 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 13.0" "Cell type enhanced" "Detected in many" "Adipocytes: 779.5;Adrenal medulla cells: 212.7;Brain excitatory neurons: 297.0;Brain inhibitory neurons: 249.0;Epicardial cells: 347.9;Mesothelial cells: 278.2;Other brain neurons: 157.5;pDCs: 319.0;Pituitary stem cells: 380.4" "Cell type enhanced" "Detected in all" "hippocampal dentate gyrus: 1189.9" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 7.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "plasmacytoid DC: 2.6" "Lineage enriched" "Detected in single" 5 "dendritic cells: 2.6" "Cancer enhanced" "Detected in some" "Neuroblastoma: 14.1" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Kidney - Fibroblasts, Minor Salivary Gland - Adipocytes (Minor salivary gland), Spleen - Fibroblasts_1, Spleen - Fibroblasts_2, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029919, HPA052141, HPA075592" Approved Approved "Plasma membrane" "Intracellular and membrane" Receptor NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 35: Neurons - Synaptic function & neurogenesis" 2 "Plasma membrane" "HPA029919: , HPA052141: , HPA075592: " "unprognostic (3.95e-2)" "unprognostic (5.14e-2)" "unprognostic (1.08e-1)" "unprognostic (1.54e-1)" "unprognostic (9.10e-2)" "unprognostic (7.99e-2)" "unprognostic (3.95e-2)" "unprognostic (1.66e-2)" "unprognostic (5.76e-3)" "unprognostic (5.07e-2)" "unprognostic (1.88e-1)" "unprognostic (1.04e-1)" "unprognostic (2.23e-1)" PLXNB1 "KIAA0407, PLXN5, SEP" ENSG00000164050 "Plexin B1" O43157 3 48403854-48430086 "Plasma proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 172.1;Distal convoluted tubule cells: 121.2;Ependymal cells: 95.7;Proximal tubule cells: 103.2" "Cell type enhanced" "Detected in many" "astrocyte: 212.9;Bergmann glia: 106.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Breast - Breast glandular cells, Prostate - Prostate basal glandular cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040586 Enhanced "Intracellular and membrane" Receptor NA NA 26000000 "Cluster 74: Non-specific - Signal transduction" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 28: Astrocytes - Homeostasis & neuron support" 14 "HPA040586: " "unprognostic (1.39e-1)" "unprognostic (1.13e-1)" "unprognostic (9.94e-2)" "unprognostic (1.13e-1)" "unprognostic (2.46e-1)" "unprognostic (2.69e-1)" "unprognostic (3.82e-1)" "unprognostic (1.01e-1)" "unprognostic (3.32e-3)" "unprognostic (8.50e-2)" "unprognostic (1.43e-3)" "unprognostic (1.68e-2)" "unprognostic (7.05e-3)" "unprognostic (3.56e-1)" "unprognostic (1.32e-1)" "unprognostic (8.49e-2)" "unprognostic (1.09e-1)" "unprognostic (8.96e-2)" "unprognostic (1.43e-2)" "unprognostic (5.85e-2)" "unprognostic (6.87e-3)" "unprognostic (4.35e-2)" "unprognostic (1.03e-1)" "unprognostic (1.46e-1)" "unprognostic (9.65e-3)" "unprognostic (2.17e-3)" "unprognostic (4.78e-2)" "unprognostic (2.05e-2)" "unprognostic (1.20e-1)" "unprognostic (2.60e-2)" "unprognostic (3.42e-1)" PLXNB2 "KIAA0315, MM1, PLEXB2" ENSG00000196576 "Plexin B2" O15031 22 50274979-50307646 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 208.0;Esophageal apical cells: 196.3;Foveolar cells: 205.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 21 "classical monocyte: 11.1;intermediate monocyte: 16.4;myeloid DC: 8.3;non-classical monocyte: 21.3;plasmacytoid DC: 6.6" "Group enriched" "Detected in many" 25 "dendritic cells: 8.3;monocytes: 21.3" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003100 Uncertain NA NA 25000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 66: Non-specific - Mitochondria" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 31 "HPA003100: " "unprognostic (5.60e-2)" "unprognostic (8.44e-2)" "unprognostic (8.55e-2)" "unprognostic (6.54e-3)" "unprognostic (3.87e-2)" "unprognostic (1.52e-1)" "unprognostic (2.02e-1)" "unprognostic (4.61e-2)" "unprognostic (9.20e-2)" "unprognostic (2.39e-1)" "potential prognostic favorable (1.72e-5)" "unprognostic (1.17e-2)" "unprognostic (3.16e-1)" "unprognostic (2.03e-2)" "unprognostic (2.60e-2)" "unprognostic (1.30e-1)" "unprognostic (1.14e-1)" "unprognostic (1.74e-1)" "unprognostic (2.00e-1)" "unprognostic (4.65e-3)" "unprognostic (9.00e-2)" "unprognostic (3.55e-2)" "unprognostic (3.73e-2)" "unprognostic (2.15e-1)" "unprognostic (1.43e-2)" "unprognostic (1.56e-3)" "unprognostic (2.01e-1)" "unprognostic (3.82e-2)" "unprognostic (1.80e-1)" "unprognostic (9.53e-2)" "unprognostic (4.04e-1)" PLXNB3 "PLEXB3, PLEXR, PLXN6" ENSG00000198753 "Plexin B3" Q9ULL4 X 153764196-153779346 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Neurogenesis Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 85.1;intestine: 56.5" "Cell type enhanced" "Detected in some" "Astrocytes: 56.8;Bergmann glia: 25.6;Ependymal cells: 13.8;Megakaryocytes: 6.2;Oligodendrocyte progenitor cells: 24.6;Oligodendrocytes: 71.4" "Cell type enhanced" "Detected in many" "astrocyte: 62.5;committed oligodendrocyte precursor: 86.8;oligodendrocyte: 70.9" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 47.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 52.1" "Stomach - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048046 Enhanced NA NA 29000 "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 3 "HPA048046: " "unprognostic (6.05e-2)" "unprognostic (2.40e-3)" "unprognostic (1.35e-2)" "unprognostic (1.07e-1)" "unprognostic (4.40e-2)" "unprognostic (2.94e-1)" "unprognostic (1.90e-1)" "unprognostic (1.57e-1)" "unprognostic (1.06e-1)" "validated prognostic unfavorable (3.03e-12)" "validated prognostic unfavorable (4.54e-6)" "potential prognostic unfavorable (1.13e-7)" "unprognostic (1.08e-3)" "unprognostic (3.26e-3)" "unprognostic (3.72e-1)" "unprognostic (1.49e-2)" "unprognostic (1.12e-1)" "unprognostic (1.44e-2)" "unprognostic (3.60e-1)" "unprognostic (2.61e-1)" "unprognostic (4.24e-3)" "unprognostic (1.76e-1)" "unprognostic (4.50e-3)" "unprognostic (2.87e-2)" "unprognostic (1.27e-1)" "unprognostic (7.17e-2)" "unprognostic (2.02e-1)" "unprognostic (1.30e-3)" PLXNC1 "CD232, VESPR" ENSG00000136040 "Plexin C1" O60486 12 94148577-94307675 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 5 "Neutrophils: 3897.8" "Cell type enhanced" "Detected in all" "fibroblast: 346.8" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 51.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 16.5" "Group enriched" "Detected in all" 4 "granulocytes: 16.5;monocytes: 8.7" "Cancer enhanced" "Detected in many" "Myeloma: 34.9;skin cancer: 21.8" "Breast - T-cells, Spleen - Neutrophils_2, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066899 Approved Mitochondria NA NA 74000 "Cluster 7: Non-specific - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 2 Mitochondria "HPA066899: " "unprognostic (1.80e-2)" "unprognostic (2.28e-1)" "unprognostic (1.83e-1)" "unprognostic (8.89e-2)" "unprognostic (1.02e-1)" "unprognostic (1.67e-2)" "unprognostic (2.21e-1)" "unprognostic (5.30e-2)" "unprognostic (1.78e-2)" "unprognostic (1.17e-1)" "unprognostic (6.92e-3)" "unprognostic (1.35e-1)" "unprognostic (5.36e-2)" "unprognostic (7.63e-3)" "unprognostic (8.56e-2)" "unprognostic (2.21e-2)" "unprognostic (7.10e-3)" "unprognostic (6.25e-2)" "unprognostic (2.10e-2)" "unprognostic (8.12e-3)" "potential prognostic unfavorable (9.44e-5)" "unprognostic (2.57e-3)" "unprognostic (3.39e-1)" "unprognostic (2.67e-1)" "unprognostic (7.18e-2)" "unprognostic (1.61e-2)" "unprognostic (2.38e-1)" "unprognostic (2.20e-2)" "unprognostic (2.71e-2)" "unprognostic (1.67e-2)" "unprognostic (2.55e-2)" PLXND1 KIAA0620 ENSG00000004399 "Plexin D1" Q9Y4D7 3 129555214-129606676 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Developmental protein, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 56.7;Endometrial stromal cells: 77.1;Hepatic stellate cells: 58.1;Hofbauer cells: 154.3;Kupffer cells: 78.9;Leydig cells: 64.0;Lymphatic endothelial cells: 93.2;Macrophages: 114.6;monocytes: 64.7;Pericytes: 96.5;Vascular endothelial cells: 132.4" "Cell type enhanced" "Detected in many" "endothelial cell: 90.1;pericyte: 70.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 10.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells" "Group enriched" "Detected in all" 4 "amygdala: 36.6;basal ganglia: 33.1;cerebral cortex: 27.4;hippocampal formation: 26.3" "Low region specificity" "Detected in all" CAB020819 Approved NA NA 11000000 "Cluster 30: Non-specific - DNA binding" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 7 "CAB020819: " "unprognostic (9.56e-2)" "potential prognostic unfavorable (7.57e-5)" "unprognostic (1.65e-2)" "unprognostic (2.24e-1)" "unprognostic (1.30e-1)" "unprognostic (3.09e-2)" "unprognostic (3.09e-2)" "unprognostic (2.55e-2)" "unprognostic (9.09e-3)" "unprognostic (3.41e-1)" "unprognostic (2.82e-3)" "unprognostic (2.03e-2)" "unprognostic (1.48e-2)" "unprognostic (4.42e-2)" "unprognostic (6.39e-2)" "unprognostic (3.81e-2)" "unprognostic (3.69e-3)" "unprognostic (1.05e-3)" "unprognostic (2.21e-1)" "unprognostic (1.29e-2)" "unprognostic (1.70e-1)" "unprognostic (2.51e-1)" "unprognostic (1.41e-2)" "unprognostic (8.94e-3)" "unprognostic (6.11e-2)" "unprognostic (3.90e-2)" "unprognostic (2.04e-1)" "unprognostic (2.97e-1)" "unprognostic (1.02e-1)" "unprognostic (3.61e-1)" "unprognostic (1.45e-2)" PM20D1 "Cps1, FLJ32569" ENSG00000162877 "Peptidase M20 domain containing 1" Q6GTS8 1 205828025-205850132 "Enzymes, Predicted secreted proteins" "Lipid metabolism" "Hydrolase, Lyase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "pancreas: 73.6;skin 1: 32.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 64.9;Cone photoreceptor cells: 29.0;Epicardial cells: 13.6;Myonuclei: 12.6;Pancreatic acinar cells: 42.8;Retinal ganglion cells: 50.2;Retinal horizontal cells: 20.0" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 12.9" "Cancer enriched" "Detected in some" 18 "Bladder Urothelial Carcinoma (TCGA): 20.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 2.2" "Lineage enriched" "Detected in single" 6 "T-cells: 2.2" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Skin - Sebaceous gland cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted to digestive system" Enzyme NA NA 3200000 "Cluster 8: Pancreas - Proteolysis" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 5 "unprognostic (2.66e-1)" "unprognostic (5.32e-3)" "unprognostic (7.54e-2)" PM20D2 "ACY1L2, bA63L7.3" ENSG00000146281 "Peptidase M20 domain containing 2" Q8IYS1 6 89146055-89165565 "Enzymes, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 202.7;Thymic myoid cells: 240.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030325, HPA030326, HPA030327" Approved Enhanced Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 20 Nucleoplasm "HPA030325: , HPA030326: , HPA030327: " "unprognostic (1.02e-2)" "unprognostic (9.96e-3)" "unprognostic (1.66e-1)" "unprognostic (9.32e-2)" "unprognostic (1.39e-1)" "unprognostic (5.67e-3)" "unprognostic (1.96e-1)" "unprognostic (6.04e-2)" "unprognostic (9.68e-2)" "unprognostic (7.71e-2)" "potential prognostic favorable (9.96e-5)" "unprognostic (4.46e-3)" "unprognostic (6.93e-3)" "unprognostic (5.02e-3)" "potential prognostic unfavorable (8.29e-5)" "unprognostic (2.02e-1)" "unprognostic (1.62e-2)" "unprognostic (2.96e-2)" "unprognostic (6.43e-2)" "unprognostic (1.55e-1)" "unprognostic (2.36e-1)" "unprognostic (9.54e-2)" "unprognostic (5.22e-2)" "unprognostic (1.59e-1)" "unprognostic (5.79e-3)" "unprognostic (6.73e-3)" "unprognostic (7.32e-2)" "unprognostic (2.43e-1)" "unprognostic (4.60e-2)" "unprognostic (3.13e-1)" "unprognostic (2.25e-1)" PMAIP1 "APR, NOXA" ENSG00000141682 "Phorbol-12-myristate-13-acetate-induced protein 1" Q13794 18 59899996-59904305 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 83.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 663.3;Endometrial ciliated cells: 347.8;Endometrial glandular cells: 391.5;Endometrial luminal cells: 492.5;Endometrial secretory cells: 414.5;Epididymal basal cells: 659.3;Esophageal apical cells: 770.5;Esophageal suprabasal cells: 410.2;Ocular epithelial cells: 809.6;Suprabasal keratinocytes: 577.1;Syncytiotrophoblasts: 442.0;Urothelial cells: 377.0" "Cell type enriched" "Detected in some" 8 "endothelial cell: 105.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 170.1" "Lineage enriched" "Detected in all" 5 "granulocytes: 170.1" "Cancer enhanced" "Detected in many" "lymphoma: 208.8" "Pituitary gland - Corticotropes, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA051063 Uncertain Uncertain Vesicles NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 47: Endothelial cells - Vasculature" "Cluster 13: Non-specific - Mixed function" "Cluster 100: Stratified epithelial cells - Barrier functions" 12 Vesicles "HPA051063: " "unprognostic (2.94e-1)" "unprognostic (1.52e-2)" "unprognostic (3.39e-1)" "unprognostic (2.50e-1)" "unprognostic (2.78e-1)" "unprognostic (6.48e-2)" "unprognostic (1.03e-2)" "unprognostic (4.06e-1)" "unprognostic (6.29e-2)" "unprognostic (2.27e-1)" "potential prognostic unfavorable (8.62e-6)" "unprognostic (1.43e-1)" "potential prognostic unfavorable (2.91e-4)" "unprognostic (3.72e-1)" "unprognostic (1.30e-3)" "potential prognostic unfavorable (4.11e-4)" "unprognostic (2.19e-2)" "unprognostic (1.26e-1)" "unprognostic (1.33e-1)" "unprognostic (1.93e-1)" "unprognostic (4.88e-3)" "potential prognostic unfavorable (2.37e-5)" "unprognostic (4.86e-2)" "unprognostic (9.02e-3)" "potential prognostic favorable (9.48e-4)" "unprognostic (1.29e-1)" "unprognostic (1.72e-1)" "unprognostic (1.68e-1)" "unprognostic (6.99e-2)" "unprognostic (1.10e-1)" PMCH MCH ENSG00000183395 "Pro-melanin concentrating hormone" P20382 12 102196459-102197833 "Predicted secreted proteins" "Differentiation, Spermatogenesis" "Developmental protein, Hormone, Neuropeptide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 720 "brain: 713.2" "Cell type enriched" "Detected in some" 16 "Other brain neurons: 81.0" "Cell type enhanced" "Detected in some" "mammillary body: 4.7;splatter: 8.5" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 3.2" "Region enhanced" "Detected in many" "hypothalamus: 202.9;thalamus: 127.6" "Immune cell enriched" "Detected in some" 10 "T-reg: 9.6" "Lineage enriched" "Detected in single" 86 "T-cells: 9.6" "Low cancer specificity" "Detected in single" "Group enriched" "Detected in many" 129 "hypothalamus: 624.4;thalamus: 340.0" "Region enriched" "Detected in many" 32 "hypothalamus: 125.8" "HPA046055, HPA061884" Enhanced Supported "Secreted to blood" Hormone NA NA 274000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 36: Brain & Liver - Signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 9: T-cells - Adaptive immunity: Regulation" 3 "HPA046055: , HPA061884: " "unprognostic (1.05e-1)" "unprognostic (2.34e-1)" "unprognostic (7.37e-2)" "unprognostic (2.35e-3)" "unprognostic (3.74e-3)" "unprognostic (1.48e-1)" "potential prognostic unfavorable (3.43e-5)" "unprognostic (3.15e-1)" "unprognostic (4.25e-1)" "unprognostic (2.35e-1)" "unprognostic (9.75e-3)" PMEL "D12S53E, gp100, HMB-45, HMB45, ME20, Pmel17, SI, SIL, SILV" ENSG00000185664 "Premelanosome protein" P40967 12 55954105-55973317 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Melanin biosynthesis" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 31.6;skin 1: 109.1" "Group enriched" "Detected in many" 51 "Melanocytes: 3051.8;Retinal pigment epithelial cells: 780.1" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in all" 552 "Skin Cutaneous Melanoma (TCGA): 7481.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 49 "skin cancer: 3389.1" "Liver - Hepatocytes, Skin - Melanocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA031649 Enhanced Supported "Endoplasmic reticulum,Golgi apparatus" "Intracellular and membrane" Other NA NA 4000000 "Cluster 37: Skin - Keratinization" "Cluster 15: Non-specific - Transcription" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 61: Schwann cells & Melanocytes - Mixed function" "Endoplasmic reticulum" "Golgi apparatus" "HPA031649: " "unprognostic (9.14e-2)" "unprognostic (2.57e-1)" "unprognostic (1.91e-1)" "unprognostic (2.05e-2)" "unprognostic (2.05e-2)" "unprognostic (2.50e-2)" "unprognostic (1.35e-1)" "unprognostic (1.65e-1)" "potential prognostic favorable (9.28e-4)" "unprognostic (1.25e-1)" "unprognostic (1.63e-1)" "unprognostic (3.91e-1)" "unprognostic (2.70e-2)" "unprognostic (7.93e-3)" "unprognostic (1.48e-1)" "unprognostic (7.72e-3)" "unprognostic (1.53e-1)" "unprognostic (2.29e-1)" "unprognostic (2.29e-2)" "unprognostic (2.05e-2)" "unprognostic (6.08e-2)" "unprognostic (1.04e-1)" "unprognostic (1.78e-2)" "unprognostic (9.68e-2)" "unprognostic (4.82e-2)" "unprognostic (2.84e-1)" "unprognostic (1.80e-1)" "unprognostic (9.29e-2)" "unprognostic (1.02e-1)" PMEPA1 "STAG1, TMEPAI" ENSG00000124225 "Prostate transmembrane protein, androgen induced 1" Q969W9 20 57648392-57711536 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Signal transduction inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 127.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 339.3;Müller glia: 476.6;Pancreatic duct cells: 905.2;pDCs: 247.6;Pericytes: 247.8;Prostatic glandular cells: 764.8;Salivary basal cells: 296.8;Salivary myoepithelial cells: 250.4;Schwann cells: 458.5" "Cell type enhanced" "Detected in all" "pericyte: 206.7" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 277.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "naive B-cell: 6.3;plasmacytoid DC: 23.9" "Group enriched" "Detected in many" 8 "B-cells: 6.3;dendritic cells: 23.9" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Prostate - Prostate glandular cells, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072291 Supported Vesicles "Intracellular and membrane" Other NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 74: Non-specific - Signal transduction" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 7 Vesicles "HPA072291: " "unprognostic (1.07e-1)" "unprognostic (2.69e-2)" "unprognostic (4.21e-2)" "potential prognostic unfavorable (3.40e-6)" "unprognostic (1.80e-1)" "unprognostic (4.07e-1)" "unprognostic (3.73e-2)" "unprognostic (5.82e-3)" "unprognostic (2.25e-2)" "unprognostic (1.01e-2)" "unprognostic (7.48e-2)" "potential prognostic favorable (9.65e-4)" "unprognostic (7.51e-3)" "unprognostic (8.28e-2)" "unprognostic (7.85e-2)" "validated prognostic unfavorable (3.37e-5)" "validated prognostic unfavorable (1.03e-4)" "unprognostic (3.18e-3)" "unprognostic (3.58e-2)" "unprognostic (1.81e-2)" "potential prognostic unfavorable (9.37e-4)" "unprognostic (7.48e-3)" "unprognostic (4.58e-2)" "unprognostic (1.81e-1)" "unprognostic (2.56e-1)" "unprognostic (3.04e-3)" "unprognostic (1.71e-1)" "unprognostic (1.91e-1)" "unprognostic (8.30e-2)" "unprognostic (1.49e-1)" "unprognostic (2.05e-1)" PMF1 ENSG00000160783 "Polyamine modulated factor 1" Q6P1K2 1 156212993-156240042 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 18.8;Bergmann glia: 28.0;Brain excitatory neurons: 14.3;Brain inhibitory neurons: 11.9;Choroid plexus epithelial cells: 33.8;Ependymal cells: 18.4;Gastric chief cells: 9.8;Microglia: 20.4;Oligodendrocyte progenitor cells: 23.5;Oligodendrocytes: 32.9;Other brain neurons: 12.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "HPA034583, HPA071854" Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 22: Non-specific - Basic cellular functions" 37 Nucleoplasm "Golgi apparatus, Vesicles" "HPA034583: , HPA071854: " "unprognostic (2.67e-2)" "unprognostic (6.35e-2)" "unprognostic (2.71e-1)" "unprognostic (3.55e-1)" "unprognostic (4.67e-2)" "unprognostic (1.33e-1)" "unprognostic (4.08e-2)" "unprognostic (2.50e-3)" "unprognostic (2.34e-2)" "unprognostic (1.46e-1)" "unprognostic (1.46e-3)" "unprognostic (1.78e-2)" "unprognostic (8.38e-3)" "unprognostic (1.55e-2)" "unprognostic (1.26e-2)" "unprognostic (2.94e-2)" "unprognostic (8.46e-2)" "unprognostic (3.04e-2)" "unprognostic (7.38e-2)" "unprognostic (1.01e-1)" "unprognostic (1.21e-1)" "unprognostic (5.26e-2)" "unprognostic (1.22e-1)" "unprognostic (2.20e-1)" "unprognostic (3.04e-1)" "unprognostic (3.27e-1)" "unprognostic (1.45e-1)" "unprognostic (4.58e-2)" "unprognostic (1.19e-1)" "unprognostic (1.10e-1)" "unprognostic (1.49e-1)" PMF1-BGLAP ENSG00000260238 "PMF1-BGLAP readthrough" 1 156212982-156243332 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial luminal cells: 6.1;Ovarian stromal cells: 6.9;Salivary basal cells: 7.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA034583, HPA071854" Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 24: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 67: Plasma cells - Plasma cell differentiation" Nucleoplasm "Golgi apparatus, Vesicles" "HPA034583: , HPA071854: " "potential prognostic unfavorable (1.96e-4)" "unprognostic (2.07e-1)" "unprognostic (2.78e-1)" "unprognostic (3.83e-2)" "unprognostic (2.77e-1)" "unprognostic (3.36e-2)" "unprognostic (4.96e-2)" "unprognostic (1.24e-2)" "unprognostic (9.72e-2)" "unprognostic (1.69e-1)" "unprognostic (2.45e-1)" "potential prognostic unfavorable (5.03e-4)" "unprognostic (1.74e-2)" "unprognostic (2.35e-2)" "unprognostic (1.97e-2)" "unprognostic (3.76e-2)" "unprognostic (7.63e-2)" "unprognostic (1.24e-1)" "unprognostic (3.55e-2)" "unprognostic (1.44e-2)" "unprognostic (4.34e-1)" "unprognostic (1.62e-1)" "unprognostic (1.01e-1)" "unprognostic (1.32e-2)" "unprognostic (1.85e-1)" "unprognostic (3.73e-2)" "unprognostic (1.82e-2)" "unprognostic (2.01e-1)" PMFBP1 ENSG00000118557 "Polyamine modulated factor 1 binding protein 1" Q8TBY8 16 72112157-72176878 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 12.7;testis: 20.0" "Cell type enhanced" "Detected in many" "Early spermatids: 152.4;Late primary spermatocytes: 83.4;Late spermatids: 464.5;Paneth cells: 54.1;Retinal amacrine cells: 53.9;Retinal horizontal cells: 224.4" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 13.3" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 20.7" "Region enhanced" "Detected in all" "pons: 30.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Skin - Sebaceous gland cells, Testis - Late spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA075825 Approved Uncertain "Nucleoplasm,Cell Junctions,Acrosome,Connecting piece,Flagellar centriole,Mid piece,Principal piece" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 22: Epididymis - Mixed function" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 109: Neurons - Neuronal signaling" 2 "Nucleoplasm, Connecting piece" "Cell Junctions, Acrosome, Flagellar centriole, Mid piece, Principal piece" "HPA075825: " "unprognostic (4.09e-2)" "unprognostic (2.94e-2)" "unprognostic (2.19e-2)" "unprognostic (2.94e-1)" "unprognostic (1.26e-1)" "unprognostic (1.08e-1)" "unprognostic (7.31e-2)" "potential prognostic unfavorable (1.34e-8)" "unprognostic (3.13e-1)" "unprognostic (7.98e-3)" "potential prognostic unfavorable (9.31e-4)" "unprognostic (1.46e-2)" "unprognostic (2.02e-1)" "unprognostic (2.57e-1)" "unprognostic (2.81e-1)" "unprognostic (2.70e-1)" "unprognostic (5.08e-3)" "unprognostic (1.32e-1)" "unprognostic (1.52e-1)" "unprognostic (7.23e-2)" "unprognostic (2.04e-1)" "unprognostic (4.78e-2)" "unprognostic (2.77e-1)" "unprognostic (4.20e-2)" PMIS2 IFITMD9 ENSG00000283758 "PMIS2 transmembrane protein" A0A1W2PS18 19 35586161-35587296 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Group enriched" "Detected in some" 62 "Early spermatids: 14.7;Late primary spermatocytes: 12.0;Late spermatids: 34.4" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 13 "cerebellum: 3.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 35: Non-specific - DNA binding" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" PML "MYL, RNF71, TRIM19" ENSG00000140464 "PML nuclear body scaffold" P29590 15 73994673-74047827 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Apoptosis, Biological rhythms, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation" "Activator, DNA-binding, Transferase" "Cancer-related genes, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cell type enhanced" "Detected in all" "endothelial cell: 57.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008312, CAB010194, CAB016304" Supported Enhanced "Nuclear bodies" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 19: Astrocytes - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 191 "Nuclear bodies" "CAB010194: , CAB016304: , HPA008312: " "unprognostic (7.43e-3)" "unprognostic (3.21e-3)" "unprognostic (5.46e-3)" "unprognostic (1.71e-2)" "unprognostic (9.32e-2)" "unprognostic (2.04e-1)" "unprognostic (2.10e-2)" "unprognostic (5.35e-2)" "unprognostic (1.13e-1)" "unprognostic (1.00e-1)" "unprognostic (1.36e-1)" "unprognostic (2.47e-1)" "unprognostic (1.97e-1)" "unprognostic (1.42e-3)" "unprognostic (3.97e-2)" "unprognostic (4.55e-2)" "potential prognostic unfavorable (9.65e-4)" "unprognostic (1.19e-1)" "unprognostic (1.39e-1)" "unprognostic (1.26e-1)" "unprognostic (4.32e-2)" "unprognostic (1.95e-3)" "unprognostic (2.36e-2)" "unprognostic (1.88e-2)" "unprognostic (3.79e-1)" "unprognostic (1.01e-2)" "unprognostic (1.54e-1)" "unprognostic (6.14e-2)" "unprognostic (2.99e-2)" "unprognostic (7.13e-2)" "unprognostic (1.11e-1)" PMM1 Sec53 ENSG00000100417 "Phosphomannomutase 1" Q92871 22 41576900-41589871 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 5 "Esophageal apical cells: 878.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030712, HPA074950" Uncertain Supported Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 66: Non-specific - Mitochondria" "Cluster 84: Apical squamous epithelium - Cornification" 5 Cytosol "HPA030712: , HPA074950: " "unprognostic (5.40e-2)" "unprognostic (8.09e-2)" "unprognostic (1.97e-2)" "potential prognostic favorable (5.81e-5)" "unprognostic (9.38e-2)" "unprognostic (3.72e-3)" "unprognostic (2.14e-1)" "unprognostic (1.48e-1)" "unprognostic (4.05e-2)" "unprognostic (2.36e-2)" "validated prognostic favorable (4.12e-7)" "validated prognostic favorable (5.87e-4)" "unprognostic (1.70e-2)" "unprognostic (1.60e-2)" "unprognostic (1.14e-2)" "unprognostic (7.45e-2)" "unprognostic (1.38e-1)" "unprognostic (2.93e-1)" "unprognostic (9.30e-2)" "unprognostic (6.45e-2)" "unprognostic (6.60e-3)" "unprognostic (1.19e-3)" "unprognostic (1.77e-2)" "unprognostic (1.10e-2)" "unprognostic (2.22e-2)" "unprognostic (6.15e-2)" "unprognostic (5.60e-3)" "unprognostic (1.71e-2)" "unprognostic (9.56e-2)" "unprognostic (1.63e-1)" "unprognostic (1.26e-1)" PMM2 "CDG1, CDG1a, CDGS, PMI, PMI1" ENSG00000140650 "Phosphomannomutase 2" O15305 16 8788823-8862534 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Isomerase "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epicardial cells: 313.8;Late spermatids: 458.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 8 "basophil: 207.1" "Lineage enriched" "Detected in all" 12 "granulocytes: 207.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063649 Approved Approved "Nucleoplasm,Microtubules,Primary cilium,Primary cilium tip,Cytosol" NA NA 39000 "Cluster 46: Basophils - Proteolysis" "Cluster 70: Non-specific - Protein processing" "Cluster 36: Choroid plexus - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 8: Non-specific - Secretory pathway" 2 "Nucleoplasm, Cytosol" "Microtubules, Primary cilium, Primary cilium tip" "HPA063649: " "unprognostic (1.37e-1)" "potential prognostic unfavorable (7.71e-5)" "unprognostic (6.45e-2)" "unprognostic (1.65e-1)" "unprognostic (2.93e-3)" "unprognostic (4.39e-2)" "unprognostic (1.40e-2)" "unprognostic (2.56e-1)" "unprognostic (1.04e-2)" "unprognostic (1.36e-1)" "validated prognostic unfavorable (6.21e-4)" "validated prognostic unfavorable (1.71e-4)" "unprognostic (2.06e-2)" "unprognostic (1.90e-3)" "potential prognostic unfavorable (4.19e-4)" "unprognostic (8.93e-3)" "potential prognostic unfavorable (2.32e-4)" "unprognostic (1.05e-1)" "unprognostic (1.08e-1)" "unprognostic (1.65e-1)" "unprognostic (1.72e-1)" "unprognostic (2.43e-2)" "unprognostic (4.53e-2)" "unprognostic (7.02e-2)" "unprognostic (4.00e-2)" "unprognostic (2.65e-1)" "unprognostic (1.63e-1)" "unprognostic (1.01e-1)" "unprognostic (9.97e-2)" "unprognostic (4.55e-3)" "unprognostic (1.57e-1)" PMP2 "FABP8, M-FABP, MP2" ENSG00000147588 "Peripheral myelin protein 2" P02689 8 81440326-81447439 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Transport "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 21 "brain: 388.6" "Cell type enhanced" "Detected in some" "Astrocytes: 117.2;Bergmann glia: 38.7;Müller glia: 63.6;Oligodendrocyte progenitor cells: 106.3;Oligodendrocytes: 79.6;Schwann cells: 160.9" "Group enriched" "Detected in many" 10 "astrocyte: 203.9;Bergmann glia: 70.2;committed oligodendrocyte precursor: 146.1;oligodendrocyte: 94.0;oligodendrocyte precursor cell: 117.0" "Cancer enriched" "Detected in some" 64 "Glioblastoma Multiforme (TCGA): 397.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 5.9;skin cancer: 15.5" "Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Not detected" "Not detected" "Region enriched" "Detected in many" 9 "spinal cord: 1781.2" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 61: Schwann cells & Melanocytes - Mixed function" 1 "unprognostic (2.30e-1)" "unprognostic (2.02e-2)" "unprognostic (1.84e-2)" "unprognostic (2.00e-2)" PMP22 "CMT1A, GAS3, HMSNIA, HNPP, Sp110" ENSG00000109099 "Peripheral myelin protein 22" Q01453 17 15229773-15272292 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cancer-related genes, Charcot-Marie-Tooth disease, Deafness, Dejerine-Sottas syndrome, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 388.0;Enterocytes: 1064.0;Fibroblasts: 459.4;Hofbauer cells: 1289.5;Melanocytes: 443.3;Myosatellite cells: 291.5;Schwann cells: 1577.5" "Cell type enhanced" "Detected in many" "fibroblast: 260.3;oligodendrocyte: 324.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 32.3;eosinophil: 43.1;plasmacytoid DC: 23.9" "Group enriched" "Detected in many" 22 "dendritic cells: 23.9;granulocytes: 43.1" "Group enriched" "Detected in many" 5 "Adrenocortical cancer: 276.5;Brain cancer: 135.3;Rhabdoid: 121.6;skin cancer: 209.0;testis cancer: 307.6" "Colon - Enteric glia cells, Lung - Fibroblasts_1, Pituitary gland - Endothelial cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "spinal cord: 1023.1" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 30: White matter - Myelination" "Cluster 69: Skin cancer - ECM organization" "Cluster 61: Schwann cells & Melanocytes - Mixed function" 53 "unprognostic (1.11e-1)" "unprognostic (7.96e-2)" "unprognostic (4.50e-1)" "unprognostic (4.98e-3)" "unprognostic (1.21e-1)" "potential prognostic unfavorable (1.57e-6)" "unprognostic (2.13e-2)" "potential prognostic unfavorable (1.55e-6)" "unprognostic (7.35e-3)" "unprognostic (2.22e-2)" "unprognostic (9.55e-3)" "unprognostic (1.72e-2)" "unprognostic (1.31e-1)" "unprognostic (8.38e-2)" "unprognostic (1.63e-1)" "unprognostic (1.23e-1)" "unprognostic (3.48e-2)" "unprognostic (1.08e-2)" "unprognostic (3.72e-1)" "unprognostic (2.38e-2)" "unprognostic (2.30e-3)" "unprognostic (4.50e-2)" "unprognostic (2.72e-1)" "unprognostic (1.14e-1)" "unprognostic (6.09e-2)" "unprognostic (5.58e-2)" "unprognostic (3.59e-1)" "unprognostic (2.56e-2)" "unprognostic (6.85e-2)" "unprognostic (1.40e-1)" "unprognostic (2.32e-1)" PMPCA "Alpha-MPP, CLA1, INPP5E, KIAA0123, MAS2, SCAR2" ENSG00000165688 "Peptidase, mitochondrial processing subunit alpha" Q10713 9 136410630-136427992 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Disease variant, Intellectual disability, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 125.9;Syncytiotrophoblasts: 126.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021648, HPA063735" Supported Enhanced Mitochondria NA NA 37000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 70: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 42 Mitochondria "HPA021648: , HPA063735: " "unprognostic (7.50e-3)" "unprognostic (8.18e-2)" "unprognostic (2.52e-1)" "unprognostic (4.40e-2)" "unprognostic (3.20e-1)" "unprognostic (2.42e-1)" "unprognostic (1.02e-1)" "unprognostic (2.75e-2)" "unprognostic (1.44e-1)" "unprognostic (4.73e-2)" "potential prognostic favorable (8.00e-5)" "unprognostic (5.78e-2)" "potential prognostic favorable (2.40e-4)" "unprognostic (2.23e-2)" "unprognostic (6.68e-2)" "unprognostic (5.13e-2)" "unprognostic (2.27e-1)" "unprognostic (2.30e-2)" "unprognostic (1.00e-1)" "unprognostic (8.82e-2)" "unprognostic (2.28e-1)" "potential prognostic favorable (5.06e-4)" "unprognostic (8.82e-2)" "unprognostic (1.28e-2)" "unprognostic (8.88e-2)" "unprognostic (2.17e-2)" "unprognostic (7.24e-2)" "unprognostic (3.03e-2)" "unprognostic (5.42e-2)" "unprognostic (4.77e-2)" "unprognostic (5.79e-3)" PMPCB "beta-MPP, MAS1, MPPB, MPPP52" ENSG00000105819 "Peptidase, mitochondrial processing subunit beta" O75439 7 103297407-103331818 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 231.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040674, HPA074168" Approved Enhanced Mitochondria No No 6700 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 39: Non-specific - Transcription" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 34 Mitochondria "HPA040674: , HPA074168: " "unprognostic (1.42e-1)" "unprognostic (3.62e-1)" "unprognostic (1.94e-2)" "unprognostic (2.35e-1)" "unprognostic (2.61e-1)" "unprognostic (8.02e-2)" "unprognostic (3.20e-3)" "unprognostic (6.91e-2)" "unprognostic (7.23e-2)" "unprognostic (1.09e-3)" "potential prognostic favorable (8.51e-5)" "unprognostic (6.54e-3)" "unprognostic (6.09e-2)" "unprognostic (7.49e-2)" "unprognostic (1.07e-2)" "unprognostic (6.38e-2)" "unprognostic (2.07e-1)" "unprognostic (1.65e-1)" "unprognostic (2.20e-1)" "unprognostic (2.80e-3)" "unprognostic (1.54e-1)" "unprognostic (1.83e-1)" "unprognostic (4.39e-2)" "unprognostic (8.52e-2)" "unprognostic (5.98e-2)" "unprognostic (3.15e-1)" "unprognostic (4.51e-2)" "unprognostic (1.33e-1)" "unprognostic (2.85e-1)" "unprognostic (8.58e-2)" "unprognostic (1.90e-1)" PMS1 "MLH2, PMSL1" ENSG00000064933 "PMS1 homolog 1, mismatch repair system component" P54277 2 189784085-189877629 "Predicted intracellular proteins" "DNA damage, DNA repair" DNA-binding "Hereditary nonpolyposis colorectal cancer, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 45.4" "Cell type enhanced" "Detected in all" "Early spermatids: 506.1;Late primary spermatocytes: 327.1;Late spermatids: 992.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031013 Approved "Nucleoplasm,Nuclear bodies" No No "Cluster 24: Non-specific - Transcription" "Cluster 39: Testis - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 16 "Nuclear bodies" Nucleoplasm "HPA031013: " "unprognostic (3.68e-1)" "unprognostic (6.93e-2)" "unprognostic (1.49e-1)" "unprognostic (4.17e-2)" "unprognostic (6.84e-2)" "unprognostic (5.50e-2)" "unprognostic (1.35e-2)" "unprognostic (2.25e-2)" "unprognostic (1.19e-2)" "potential prognostic unfavorable (4.84e-4)" "unprognostic (1.44e-2)" "unprognostic (1.93e-1)" "unprognostic (2.50e-1)" "potential prognostic unfavorable (1.22e-4)" "unprognostic (5.73e-2)" "unprognostic (7.80e-2)" "unprognostic (1.99e-2)" "unprognostic (8.18e-2)" "unprognostic (5.84e-2)" "unprognostic (1.33e-2)" "unprognostic (1.49e-1)" "unprognostic (7.42e-2)" "unprognostic (9.16e-3)" "unprognostic (2.02e-1)" "unprognostic (4.31e-2)" "potential prognostic favorable (5.42e-4)" "unprognostic (2.79e-2)" "unprognostic (1.13e-1)" "unprognostic (5.11e-2)" "unprognostic (2.91e-3)" "unprognostic (1.71e-1)" PMS2 "H_DJ0042M02.9, HNPCC4, MLH4, PMS-2, PMSL2" ENSG00000122512 "PMS1 homolog 2, mismatch repair system component" P54278 7 5970925-6009130 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Endonuclease, Hydrolase, Nuclease" "Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 40.2;Proximal tubule cells: 37.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010235, HPA070310" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 36: Brain & Liver - Signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 67: Non-specific - Unknown function" "Cluster 88: Proximal tubular cells - Transmembrane transport" 14 Nucleoplasm Cytosol "CAB010235: , HPA070310: " "unprognostic (1.59e-2)" "unprognostic (2.33e-2)" "unprognostic (1.03e-1)" "unprognostic (3.46e-1)" "unprognostic (6.94e-3)" "unprognostic (4.54e-2)" "unprognostic (7.87e-2)" "unprognostic (2.09e-2)" "unprognostic (2.60e-1)" "unprognostic (1.31e-2)" "potential prognostic favorable (3.53e-4)" "unprognostic (2.32e-3)" "unprognostic (3.42e-3)" "unprognostic (2.99e-3)" "unprognostic (5.87e-2)" "unprognostic (9.14e-2)" "unprognostic (5.27e-2)" "unprognostic (3.26e-2)" "unprognostic (7.76e-2)" "unprognostic (2.64e-1)" "unprognostic (1.26e-2)" "unprognostic (4.10e-2)" "unprognostic (3.20e-3)" "unprognostic (7.36e-2)" "unprognostic (5.52e-3)" "unprognostic (7.63e-2)" "unprognostic (1.58e-1)" "unprognostic (8.54e-2)" "unprognostic (2.09e-1)" "potential prognostic unfavorable (2.57e-4)" "unprognostic (2.00e-1)" PMVK "HUMPMKI, PMK, PMKA" ENSG00000163344 "Phosphomevalonate kinase" Q15126 1 154924740-154936719 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 294.2;Esophageal apical cells: 415.9;Esophageal suprabasal cells: 432.6;Syncytiotrophoblasts: 290.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skin - Sebaceous gland cells, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029900 Approved NA NA 73000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 19: Astrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 85: Squamous epithelial cells - Keratinization" 27 "HPA029900: " "unprognostic (1.84e-1)" "unprognostic (2.32e-1)" "unprognostic (3.84e-1)" "unprognostic (1.71e-1)" "unprognostic (2.56e-2)" "unprognostic (5.04e-3)" "unprognostic (3.72e-1)" "unprognostic (5.23e-2)" "unprognostic (4.75e-3)" "unprognostic (7.86e-3)" "potential prognostic favorable (1.83e-5)" "unprognostic (5.50e-3)" "unprognostic (8.17e-3)" "unprognostic (1.10e-1)" "unprognostic (2.94e-3)" "unprognostic (6.34e-2)" "unprognostic (8.14e-2)" "unprognostic (2.30e-1)" "unprognostic (1.05e-1)" "unprognostic (2.81e-3)" "unprognostic (4.11e-2)" "unprognostic (6.33e-2)" "unprognostic (8.42e-2)" "unprognostic (3.50e-1)" "unprognostic (3.82e-2)" "unprognostic (1.90e-1)" "unprognostic (1.39e-1)" "unprognostic (2.47e-1)" "unprognostic (1.55e-1)" "unprognostic (1.69e-1)" "unprognostic (2.95e-2)" PNCK "CaMK1b, MGC45419" ENSG00000130822 "Pregnancy up-regulated nonubiquitous CaM kinase" Q6P2M8 X 153669733-153689010 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 101.3;intestine: 78.2" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 40.8;Brain inhibitory neurons: 57.5;Cone photoreceptor cells: 60.0;Extravillous trophoblasts: 94.4;Migrating cytotrophoblasts: 76.3;Other brain neurons: 61.8;Retinal bipolar cells: 45.6;Rod photoreceptor cells: 34.8;Sertoli cells: 49.3;Smooth muscle cells: 89.6;Syncytiotrophoblasts: 79.1" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 5 "Kidney Renal Clear Cell Carcinoma (TCGA): 90.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 16.6" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Cardiomyocytes, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Skin - Smooth muscle cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007458 Approved Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 35: Neurons - Synaptic function & neurogenesis" "Plasma membrane, Cytosol" "Golgi apparatus" "HPA007458: " "unprognostic (8.79e-2)" "unprognostic (2.83e-1)" "unprognostic (3.40e-1)" "unprognostic (1.58e-1)" "unprognostic (2.29e-1)" "potential prognostic favorable (2.97e-4)" "unprognostic (8.00e-3)" "unprognostic (1.50e-1)" "unprognostic (4.02e-2)" "unprognostic (7.79e-2)" "unprognostic (9.63e-2)" "unprognostic (2.60e-2)" "unprognostic (3.49e-2)" "validated prognostic unfavorable (3.90e-4)" "validated prognostic unfavorable (6.65e-6)" "unprognostic (7.11e-2)" "unprognostic (1.37e-1)" "unprognostic (7.76e-2)" "unprognostic (4.17e-3)" "unprognostic (1.10e-1)" "unprognostic (1.29e-1)" "unprognostic (1.95e-1)" "unprognostic (9.11e-3)" "unprognostic (1.50e-2)" "unprognostic (5.30e-2)" "unprognostic (5.75e-2)" "unprognostic (5.27e-2)" "unprognostic (5.08e-3)" "unprognostic (3.72e-2)" "unprognostic (5.36e-2)" PNISR "bA98I9.2, C6orf111, DKFZp564B0769, FLJ14752, SFRS18, SRrp130" ENSG00000132424 "PNN interacting serine and arginine rich protein" Q8TF01 6 99397629-99425331 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038796, HPA075076" Approved Supported "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 64: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 56: Non-specific - Sensory perception" "Cluster 94: Gonadal somatic cells - Mixed function" 2 "Nuclear speckles" "Plasma membrane, Cytosol" "HPA038796: , HPA075076: " "unprognostic (1.39e-3)" "unprognostic (8.37e-2)" "unprognostic (7.81e-3)" "unprognostic (2.64e-2)" "potential prognostic favorable (1.27e-4)" "unprognostic (9.54e-3)" "unprognostic (3.79e-2)" "unprognostic (1.29e-2)" "unprognostic (1.29e-2)" "unprognostic (3.46e-2)" "unprognostic (2.66e-2)" "unprognostic (1.59e-1)" "unprognostic (1.20e-2)" "unprognostic (2.45e-1)" "unprognostic (1.66e-2)" "unprognostic (1.49e-1)" "unprognostic (8.22e-2)" "unprognostic (6.72e-3)" "unprognostic (9.66e-2)" "unprognostic (1.18e-1)" "unprognostic (1.78e-3)" "unprognostic (2.06e-3)" "unprognostic (5.35e-3)" "unprognostic (1.51e-3)" "potential prognostic favorable (3.04e-4)" "unprognostic (1.98e-2)" "unprognostic (1.74e-1)" "unprognostic (2.71e-1)" "unprognostic (2.27e-1)" "unprognostic (2.54e-2)" PNKD "BRP17, DKFZp564N1362, DYT8, FKSG19, FPD1, KIAA1184, KIPP1184, MGC31943, MR-1, MR-1S, PDC, PKND1, TAHCCP2" ENSG00000127838 "PNKD metallo-beta-lactamase domain containing" Q8N490 2 218269651-218346793 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Disease variant, Dystonia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Heart muscle - Cardiomyocytes, Prostate - Prostate glandular cells, Skeletal muscle - Fibroblasts, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010134, HPA017068" Approved Enhanced Mitochondria NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 97: Non-specific - Cellular respiration" 5 Mitochondria "HPA010134: , HPA017068: " "unprognostic (1.62e-2)" "unprognostic (5.83e-2)" "unprognostic (3.04e-1)" "unprognostic (1.59e-2)" "unprognostic (6.36e-2)" "unprognostic (6.72e-2)" "unprognostic (5.49e-2)" "unprognostic (2.92e-1)" "unprognostic (4.13e-2)" "unprognostic (1.41e-1)" "unprognostic (4.55e-2)" "unprognostic (1.35e-1)" "unprognostic (1.79e-3)" "unprognostic (9.88e-3)" "unprognostic (2.72e-1)" "unprognostic (8.44e-2)" "unprognostic (1.43e-1)" "unprognostic (2.48e-1)" "unprognostic (2.35e-1)" "unprognostic (2.13e-1)" "unprognostic (8.26e-2)" "unprognostic (9.79e-2)" "unprognostic (2.11e-2)" "unprognostic (4.55e-2)" "unprognostic (3.82e-1)" "unprognostic (5.38e-2)" "unprognostic (5.70e-2)" "unprognostic (5.50e-2)" "unprognostic (4.59e-2)" "unprognostic (1.11e-1)" "unprognostic (1.10e-1)" PNKP PNK ENSG00000039650 "Polynucleotide kinase 3'-phosphatase" Q96T60 19 49859882-49878351 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "Hydrolase, Kinase, Multifunctional enzyme, Transferase" "Disease variant, Epilepsy, Intellectual disability, Neurodegeneration, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 139.2;Epididymal principal cells: 290.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006782 Supported Supported Nucleoplasm,Nucleoli NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 58 "Nucleoplasm, Nucleoli" "HPA006782: " "unprognostic (1.06e-1)" "unprognostic (1.42e-3)" "unprognostic (1.30e-1)" "unprognostic (1.99e-1)" "unprognostic (3.05e-2)" "unprognostic (1.77e-2)" "unprognostic (2.12e-1)" "unprognostic (9.38e-2)" "unprognostic (3.66e-1)" "unprognostic (4.54e-2)" "potential prognostic unfavorable (1.12e-4)" "unprognostic (3.11e-2)" "unprognostic (9.04e-2)" "potential prognostic unfavorable (3.09e-4)" "unprognostic (2.74e-2)" "unprognostic (5.86e-2)" "unprognostic (8.54e-3)" "unprognostic (2.34e-1)" "unprognostic (3.24e-1)" "unprognostic (2.66e-1)" "unprognostic (2.40e-2)" "unprognostic (2.44e-1)" "unprognostic (2.01e-3)" "unprognostic (1.01e-1)" "unprognostic (3.97e-1)" "unprognostic (2.61e-2)" "unprognostic (1.52e-1)" "unprognostic (3.93e-2)" "unprognostic (3.01e-1)" "unprognostic (2.22e-1)" "unprognostic (7.35e-2)" PNLDC1 "dJ195P10.2, FLJ40240, Trimmer" ENSG00000146453 "PARN like ribonuclease domain containing exonuclease 1" Q8NA58 6 159800249-159820704 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Nonsense-mediated mRNA decay" "Exonuclease, Hydrolase, Nuclease, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.6;testis: 7.9" "Cell type enriched" "Detected in many" 11 "Oocytes: 280.9" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 4.3" "Region enhanced" "Detected in many" "cerebral cortex: 16.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 1.5;Sarcoma: 2.0" "Pancreas - Ductal cells, Skin - Sebaceous gland cells, Testis - Early spermatids, Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA052026 Uncertain NA NA "Cluster 67: Testis - Mixed function" "Cluster 12: Non-specific - Vasculature" "Cluster 70: DU4475 - Unknown function" "Cluster 41: Oocytes - Oogenesis" "HPA052026: " "unprognostic (1.16e-1)" "unprognostic (7.53e-2)" "unprognostic (2.50e-3)" "unprognostic (2.53e-3)" "unprognostic (1.82e-1)" "unprognostic (2.79e-1)" "unprognostic (1.41e-1)" "unprognostic (4.90e-1)" "unprognostic (1.72e-1)" "unprognostic (6.25e-3)" PNLIP PL ENSG00000175535 "Pancreatic lipase" P16233 10 116545931-116567855 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4835 "pancreas: 419355.6" "Cell type enriched" "Detected in some" 196 "Pancreatic acinar cells: 41199.8" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4399 "Pancreatic Adenocarcinoma (TCGA): 3428.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Exocrine glandular cells" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA062430, HPA062494" Enhanced "Secreted to digestive system" Enzyme NA NA 5700000 "Cluster 8: Pancreas - Proteolysis" "Cluster 66: Non-specific - Mitochondria" "Cluster 5: Pancreatic acinar cells - Pancreatic exocrine secretion" "HPA062430: , HPA062494: " "unprognostic (1.68e-2)" "unprognostic (6.04e-2)" PNLIPRP1 PLRP1 ENSG00000187021 "Pancreatic lipase related protein 1" P54315 10 116590385-116609175 "Metabolic proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 3919 "pancreas: 10208.0" "Cell type enriched" "Detected in some" 138 "Pancreatic acinar cells: 7209.2" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 1257 "Pancreatic Adenocarcinoma (TCGA): 125.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to digestive system" "No annotated function" NA NA 190000 "Cluster 8: Pancreas - Proteolysis" "Cluster 20: Myeloma - Immune response" "Cluster 5: Pancreatic acinar cells - Pancreatic exocrine secretion" 31 "unprognostic (2.01e-1)" "unprognostic (1.34e-2)" PNLIPRP2 PLRP2 ENSG00000266200 "Pancreatic lipase related protein 2 (gene/pseudogene)" 10 116620953-116645143 "Metabolic proteins, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 109 "pancreas: 8150.3" "Cell type enriched" "Detected in some" 12 "Pancreatic acinar cells: 2695.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "cerebral cortex: 1.8;hippocampal formation: 1.4" NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Pancreatic acinar cells - Pancreatic exocrine secretion" PNLIPRP3 ENSG00000203837 "Pancreatic lipase related protein 3" Q17RR3 10 116427847-116477957 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 8.5;skin 1: 13.4" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 9.8;Early spermatids: 7.0;Esophageal apical cells: 59.7;Pancreatic acinar cells: 5.9;Suprabasal keratinocytes: 15.8" "Cell type enhanced" "Detected in single" "hippocampal CA1-3: 2.3" "Cancer enhanced" "Detected in some" "Head and Neck Squamous Cell Carcinoma (TCGA): 6.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "head and neck cancer: 6.3;skin cancer: 2.3" "Testis - Late spermatids" "Not detected" "Not detected" "HPA046202, HPA052009" Uncertain "Secreted - unknown location" Enzyme NA NA "Cluster 58: Skin - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" "HPA046202: , HPA052009: " "unprognostic (6.44e-1)" "unprognostic (1.63e-1)" "unprognostic (2.20e-1)" "unprognostic (4.78e-2)" PNMA1 MA1 ENSG00000176903 "PNMA family member 1" Q8ND90 14 73711783-73714384 "Predicted intracellular proteins" "Tumor antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 73.4;Late primary spermatocytes: 145.5;Late spermatids: 81.5;Peritubular myoid cells: 75.2;Platelets: 344.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA003817, HPA015007" Enhanced Uncertain Nucleoplasm,Cytosol NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 73: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 47: Platelets - Hemostasis" 129 Cytosol Nucleoplasm "HPA003817: , HPA015007: " "unprognostic (2.14e-1)" "unprognostic (1.37e-1)" "unprognostic (3.72e-2)" "unprognostic (1.41e-1)" "unprognostic (4.64e-2)" "unprognostic (1.60e-2)" "unprognostic (2.66e-1)" "unprognostic (3.89e-2)" "potential prognostic unfavorable (7.46e-5)" "unprognostic (2.21e-2)" "potential prognostic favorable (3.04e-5)" "unprognostic (3.37e-2)" "unprognostic (1.31e-1)" "potential prognostic unfavorable (1.08e-4)" "unprognostic (1.06e-2)" "unprognostic (2.62e-2)" "unprognostic (1.51e-1)" "unprognostic (2.41e-1)" "unprognostic (1.59e-1)" "unprognostic (1.03e-1)" "unprognostic (5.30e-2)" "unprognostic (4.55e-2)" "unprognostic (2.03e-1)" "unprognostic (9.13e-2)" "unprognostic (7.53e-3)" "unprognostic (7.81e-2)" "unprognostic (8.01e-2)" "unprognostic (5.77e-3)" "unprognostic (9.71e-2)" "unprognostic (2.90e-2)" "unprognostic (4.54e-2)" PNMA2 "MA2, RGAG2" ENSG00000240694 "PNMA family member 2" Q9UL42 8 26504701-26514092 "Predicted intracellular proteins" "Tumor antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 113.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 30.4;Brain excitatory neurons: 67.8;Brain inhibitory neurons: 116.2;Corticotrophs: 48.9;Ependymal cells: 53.1;Lactotrophs: 29.9;Müller glia: 40.8;Other brain neurons: 129.8;Pancreatic islet cells: 58.8;Retinal amacrine cells: 40.5" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 54.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 39.4" "Adipose visceral - Adipose progenitor cells, Colon - Colon enteroendocrine cells, Heart muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001936 Enhanced NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 98: Neurons - Neurotransmission & signaling" 76 "HPA001936: " "unprognostic (1.48e-1)" "unprognostic (1.64e-1)" "unprognostic (7.87e-2)" "unprognostic (9.85e-2)" "unprognostic (4.18e-3)" "unprognostic (7.98e-2)" "unprognostic (3.51e-2)" "potential prognostic favorable (2.94e-5)" "unprognostic (2.06e-2)" "unprognostic (1.56e-3)" "potential prognostic favorable (1.87e-4)" "unprognostic (3.09e-1)" "unprognostic (2.29e-3)" "unprognostic (2.84e-1)" "unprognostic (1.19e-2)" "unprognostic (2.42e-2)" "unprognostic (4.31e-2)" "unprognostic (1.94e-1)" "unprognostic (1.19e-3)" "unprognostic (1.71e-2)" "unprognostic (1.13e-1)" "unprognostic (4.40e-3)" "unprognostic (1.63e-1)" "potential prognostic unfavorable (2.09e-5)" "unprognostic (1.69e-2)" PNMA3 "MA3, MA5, MGC132756, MGC132758" ENSG00000183837 "PNMA family member 3" Q9UL41 X 153056409-153060467 "Predicted intracellular proteins" "Tumor antigen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 30.4;epididymis: 46.3;pituitary gland: 14.1;testis: 13.7" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 46.5;Brain inhibitory neurons: 43.5;Epididymal efferent duct absorptive cells: 33.0;Epididymal principal cells: 104.6;Other brain neurons: 54.0;Retinal amacrine cells: 18.4;Retinal ganglion cells: 15.5;Sertoli cells: 81.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 2.4;Neuroblastoma: 2.2" "Adipose visceral - T-cells, Heart muscle - Cardiomyocytes, Pituitary gland - Somatotropes, Prostate - T-cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" HPA047920 Approved NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 109: Neurons - Neuronal signaling" 10 "HPA047920: " "unprognostic (2.64e-2)" "unprognostic (1.85e-1)" "unprognostic (2.22e-2)" "unprognostic (1.20e-1)" "unprognostic (2.72e-1)" "unprognostic (1.53e-2)" "unprognostic (5.92e-2)" "unprognostic (2.37e-1)" "unprognostic (9.13e-2)" "unprognostic (2.30e-2)" "unprognostic (3.69e-2)" "unprognostic (1.04e-1)" "unprognostic (4.60e-3)" PNMA5 KIAA1934 ENSG00000198883 "PNMA family member 5" Q96PV4 X 152988824-152994116 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 17 "brain: 22.0;testis: 8.3" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 8.0;Brain inhibitory neurons: 6.9;Differentiating spermatogonia: 98.8;Early primary spermatocytes: 48.1;Microglia: 11.4;Other brain neurons: 22.3" "Cell type enhanced" "Detected in many" "upper-layer intratelencephalic: 24.3" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 11.0" "Region enhanced" "Detected in many" "hypothalamus: 48.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 9 "Gallbladder cancer: 241.3;Myeloma: 76.3" "Testis - Spermatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA044690, HPA073946" Enhanced Approved Centrosome NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 55 Centrosome "HPA044690: , HPA073946: " "unprognostic (9.49e-2)" "unprognostic (3.56e-2)" "unprognostic (1.29e-2)" "unprognostic (8.88e-2)" "unprognostic (1.52e-3)" "unprognostic (1.39e-2)" "unprognostic (2.29e-1)" "unprognostic (1.45e-2)" "unprognostic (1.49e-2)" "unprognostic (6.94e-2)" "unprognostic (1.35e-3)" "unprognostic (2.35e-1)" "unprognostic (9.59e-2)" "unprognostic (3.69e-2)" "unprognostic (1.42e-1)" "unprognostic (1.11e-2)" PNMA6A "MGC15827, PNMA6C" ENSG00000235961 "PNMA family member 6A" P0CW24 X 153072454-153075019 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 38.5" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 13.3;Endometrial secretory cells: 16.9;Epididymal efferent duct absorptive cells: 24.5;Epididymal principal cells: 55.1;Müller glia: 17.7;Other brain neurons: 18.6;Respiratory ionocytes: 17.8;Retinal amacrine cells: 34.6;Retinal bipolar cells: 12.4;Tuft cells: 23.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 16 "eosinophil: 2.0" "Lineage enriched" "Detected in single" 21 "granulocytes: 2.0" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Pituitary gland - Somatotropes" "HPA045007, HPA052115" Uncertain Approved Mitochondria NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 1: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 6 Mitochondria "HPA045007: , HPA052115: " "unprognostic (1.27e-1)" "unprognostic (2.64e-2)" "unprognostic (2.08e-2)" "unprognostic (4.31e-2)" "unprognostic (7.21e-2)" "unprognostic (9.56e-2)" "unprognostic (2.22e-3)" "potential prognostic favorable (2.36e-8)" "unprognostic (1.61e-2)" "unprognostic (1.88e-3)" "unprognostic (1.11e-3)" "unprognostic (5.97e-2)" "unprognostic (2.01e-1)" "unprognostic (2.13e-1)" "unprognostic (2.38e-1)" "unprognostic (5.88e-2)" "unprognostic (1.76e-1)" "unprognostic (3.16e-3)" "unprognostic (3.79e-1)" "unprognostic (4.20e-1)" "unprognostic (1.14e-1)" "unprognostic (1.96e-1)" "unprognostic (1.72e-2)" "unprognostic (2.08e-2)" PNMA6E ENSG00000214897 "PNMA family member 6E" A0A0J9YXQ4 X 153395639-153401392 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 3.0;ovary: 1.9;testis: 9.2" "Group enriched" "Detected in some" 9 "Differentiating spermatogonia: 21.9;Early primary spermatocytes: 49.6" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 1.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 3: Early primary spermatocytes - Early meiosis" "unprognostic (2.02e-1)" "unprognostic (4.19e-1)" PNMA6F PNMA6BL ENSG00000225110 "PNMA family member 6F" A0A0J9YX94 X 153317680-153321767 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 36 "brain: 25.4" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 3.2;Brain inhibitory neurons: 3.8;Other brain neurons: 13.8;Pituitary stem cells: 1.8;Somatotrophs: 2.2" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adrenal gland - Adrenal medulla cells" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 98: Neurons - Neurotransmission & signaling" PNMA8A "FLJ10781, KIAA1183L, PNMAL1" ENSG00000182013 "PNMA family member 8A" Q86V59 19 46466491-46471563 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 75.8" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 24.1;Brain inhibitory neurons: 35.0;Corticotrophs: 42.9;Differentiating spermatogonia: 34.1;Early primary spermatocytes: 29.8;Fallopian tube ciliated cells: 27.2;Gonadotrophs: 30.8;Late primary spermatocytes: 32.4;Other brain neurons: 43.6;Retinal pigment epithelial cells: 34.1;Thymic myoid cells: 27.2;Undifferentiated spermatogonia: 32.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Skeletal muscle - Fibroblasts, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "HPA012956, HPA077702" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 65: Brain - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 98: Neurons - Neurotransmission & signaling" 1 "Nucleoplasm, Nuclear bodies" Cytosol "HPA012956: , HPA077702: " "unprognostic (4.14e-1)" "unprognostic (4.13e-2)" "unprognostic (2.64e-1)" "unprognostic (6.41e-2)" "unprognostic (2.01e-1)" "unprognostic (2.29e-1)" "unprognostic (9.81e-2)" "unprognostic (1.45e-1)" "unprognostic (1.56e-2)" "unprognostic (2.37e-3)" "unprognostic (1.04e-2)" "potential prognostic favorable (2.97e-4)" "unprognostic (2.08e-1)" "unprognostic (3.37e-1)" "unprognostic (1.55e-1)" "unprognostic (2.55e-2)" "unprognostic (2.00e-1)" "unprognostic (3.09e-3)" "unprognostic (4.85e-2)" "unprognostic (2.30e-3)" "unprognostic (2.69e-2)" "unprognostic (1.31e-3)" "unprognostic (1.52e-2)" "unprognostic (7.52e-2)" "unprognostic (1.92e-1)" "unprognostic (1.31e-2)" PNMA8B "KIAA1183, PNMAL2" ENSG00000204851 "PNMA family member 8B" Q9ULN7 19 46486906-46495879 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "adrenal gland: 15.4;brain: 55.0" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "Neuroblastoma: 1.5" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" HPA054810 Enhanced NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 98: Neurons - Neurotransmission & signaling" "HPA054810: " "unprognostic (4.63e-3)" "unprognostic (4.23e-2)" "unprognostic (1.25e-1)" "unprognostic (6.76e-2)" "unprognostic (1.80e-2)" "unprognostic (1.67e-1)" "unprognostic (3.35e-3)" "potential prognostic unfavorable (8.12e-6)" "unprognostic (4.88e-2)" "unprognostic (4.08e-3)" "unprognostic (2.10e-1)" "unprognostic (1.10e-1)" "unprognostic (1.97e-1)" PNMA8C ENSG00000277531 "PNMA family member 8C" A0A1B0GUJ8 19 46424697-46428936 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 17.5;pituitary gland: 8.1" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 12.8;Brain inhibitory neurons: 12.2;Corticotrophs: 7.8;Ependymal cells: 54.5;Epididymal principal cells: 10.0;Fallopian tube ciliated cells: 7.3;Gonadotrophs: 9.7;Lactotrophs: 9.3;Other brain neurons: 24.0;Respiratory ciliated cells: 8.0;Somatotrophs: 9.0;Thyrotrophs: 8.1" "Cell type enhanced" "Detected in many" "ependymal cell: 71.8" "Cancer enriched" "Detected in single" 12 "Glioblastoma Multiforme (TCGA): 5.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 8 "Neuroblastoma: 3.0" "Colon - Colon enteroendocrine cells, Lung - Respiratory ciliated cells" "Low region specificity" "Detected in all" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 34: Ciliated cells - Cilia assembly & function" "unprognostic (4.64e-1)" PNMT PENT ENSG00000141744 "Phenylethanolamine N-methyltransferase" P11086 17 39667981-39670475 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Catecholamine biosynthesis" "Methyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 149.2;brain: 53.4" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 244.6;Breast hormone-responsive cells: 43.4;Erythrocyte progenitors: 108.8;Hematopoietic stem cells: 115.0;Mast cells: 188.4;Megakaryocyte-Erythroid progenitors: 163.3;Myosatellite cells: 66.1;Thymic myoid cells: 80.2" "Cell type enhanced" "Detected in many" "astrocyte: 13.0" "Group enriched" "Detected in many" 4 "Bladder Urothelial Carcinoma (TCGA): 82.9;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 82.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "breast cancer: 34.1" "Adrenal gland - Adrenal medulla cells, Heart muscle - Cardiomyocytes, Skin - Macrophages" "Region enhanced" "Detected in single" "basal ganglia: 1.5" "Not detected" "Not detected" "CAB017029, HPA043412, HPA051005" Enhanced NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 58: Mast cells - Allergic inflammatory responses" 1 "CAB017029: , HPA043412: , HPA051005: " "unprognostic (3.63e-2)" "unprognostic (9.16e-2)" "unprognostic (4.50e-2)" "unprognostic (2.24e-3)" "unprognostic (2.10e-2)" "unprognostic (8.16e-3)" "unprognostic (8.78e-2)" "unprognostic (1.05e-1)" "unprognostic (1.45e-1)" "unprognostic (1.55e-1)" "unprognostic (1.85e-1)" "unprognostic (8.92e-2)" "unprognostic (3.20e-2)" "unprognostic (1.26e-1)" "unprognostic (4.50e-1)" PNN memA ENSG00000100941 "Pinin, desmosome associated protein" Q9H307 14 39175183-39183220 "Essential proteins, Predicted intracellular proteins, Transporters" "mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Activator, DNA-binding" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001378 Supported Supported "Nuclear speckles" NA NA 7100 "Cluster 24: Non-specific - Transcription" "Cluster 49: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 17: Non-specific - RNA processing" 107 "Nuclear speckles" "HPA001378: " "unprognostic (1.55e-1)" "unprognostic (1.76e-1)" "unprognostic (1.46e-1)" "unprognostic (3.06e-2)" "unprognostic (1.15e-2)" "unprognostic (1.78e-1)" "unprognostic (6.30e-3)" "unprognostic (2.14e-2)" "unprognostic (7.03e-2)" "unprognostic (3.41e-3)" "unprognostic (2.13e-1)" "unprognostic (5.37e-2)" "unprognostic (3.06e-1)" "unprognostic (1.28e-3)" "unprognostic (2.00e-2)" "unprognostic (4.17e-2)" "unprognostic (6.32e-3)" "unprognostic (1.35e-2)" "unprognostic (3.33e-2)" "unprognostic (1.85e-1)" "unprognostic (5.14e-2)" "unprognostic (5.84e-2)" "unprognostic (2.49e-3)" "potential prognostic unfavorable (2.27e-4)" "potential prognostic favorable (7.38e-4)" "unprognostic (2.58e-1)" "potential prognostic unfavorable (8.11e-4)" "unprognostic (6.26e-2)" "unprognostic (1.33e-1)" "unprognostic (2.37e-2)" "unprognostic (1.65e-1)" PNO1 "KHRBP1, RRP20" ENSG00000115946 "Partner of NOB1 homolog" Q9NRX1 2 68157888-68176238 "Essential proteins, Plasma proteins, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 92.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056928 Supported Nucleoplasm,Nucleoli NA Yes "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 29: Forebrain - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 17: Non-specific - RNA processing" 40 Nucleoli Nucleoplasm "HPA056928: " "unprognostic (1.48e-2)" "potential prognostic unfavorable (2.44e-4)" "unprognostic (1.48e-1)" "unprognostic (2.05e-1)" "unprognostic (2.56e-1)" "unprognostic (3.14e-2)" "unprognostic (2.29e-1)" "unprognostic (3.26e-2)" "unprognostic (3.24e-3)" "unprognostic (5.63e-2)" "unprognostic (1.34e-2)" "unprognostic (1.43e-1)" "unprognostic (8.86e-2)" "validated prognostic unfavorable (4.59e-8)" "validated prognostic unfavorable (2.61e-4)" "unprognostic (6.19e-3)" "unprognostic (7.10e-2)" "unprognostic (7.61e-2)" "unprognostic (5.14e-2)" "unprognostic (6.80e-2)" "unprognostic (5.46e-2)" "unprognostic (1.38e-2)" "unprognostic (3.79e-3)" "unprognostic (1.05e-1)" "unprognostic (1.95e-1)" "unprognostic (2.86e-1)" "unprognostic (7.92e-2)" "unprognostic (3.64e-2)" "unprognostic (1.51e-1)" "unprognostic (4.53e-2)" "unprognostic (2.16e-1)" PNOC "N/OFQ, NOP, PPNOC" ENSG00000168081 Prepronociceptin Q13519 8 28316986-28343355 "Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Neuropeptide, Neurotransmitter, Opioid peptide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 28.3;fallopian tube: 17.1;lymphoid tissue: 23.4" "Cell type enhanced" "Detected in some" "B-cells: 43.1;Brain inhibitory neurons: 19.7;Fallopian secretory cells: 42.6;Other brain neurons: 15.5;pDCs: 35.3;Plasma cells: 100.4" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 26.1;CGE interneuron: 38.9;MGE interneuron: 71.0" "Group enriched" "Detected in many" 7 "Ovary Serous Cystadenocarcinoma (TCGA): 92.4;Uterine Corpus Endometrial Carcinoma (TCGA): 28.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 20 "memory B-cell: 232.1;naive B-cell: 261.7;plasmacytoid DC: 194.7" "Group enriched" "Detected in many" 20 "B-cells: 261.7;dendritic cells: 194.7" "Cancer enriched" "Detected in some" 11 "Rhabdoid: 338.9" "Adipose visceral - Plasma cells, Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA044507, HPA056724" Enhanced Approved Vesicles "Secreted to blood" Neuropeptide NA NA 12300 "Cluster 23: B-cells - Immunoglobulins" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 3: Rhabdoid - Membrane components" "Cluster 44: Plasma cells - Antibody production & secretion" 2 Vesicles "HPA044507: , HPA056724: " "unprognostic (1.30e-1)" "unprognostic (8.92e-2)" "potential prognostic favorable (8.65e-5)" "unprognostic (1.79e-3)" "unprognostic (9.44e-2)" "unprognostic (1.02e-1)" "unprognostic (6.93e-2)" "potential prognostic favorable (1.82e-4)" "unprognostic (5.93e-2)" "potential prognostic unfavorable (5.69e-4)" "unprognostic (5.97e-3)" "unprognostic (2.80e-2)" "unprognostic (5.22e-2)" "unprognostic (2.46e-1)" "unprognostic (3.04e-1)" "unprognostic (6.42e-2)" "unprognostic (6.34e-2)" "unprognostic (4.12e-3)" "unprognostic (2.05e-2)" "unprognostic (3.85e-1)" "unprognostic (2.96e-1)" "unprognostic (5.52e-2)" PNP "NP, PUNP" ENSG00000198805 "Purine nucleoside phosphorylase" P00491 14 20461992-20477094 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Purine salvage" "Glycosyltransferase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 299.3;epididymis: 551.4" "Cell type enhanced" "Detected in many" "Breast lactating cells: 262.7;Cytotrophoblasts: 471.8;Epididymal principal cells: 504.7;Esophageal apical cells: 204.4;Megakaryocytes: 210.2;Platelets: 208.2;Syncytiotrophoblasts: 732.4" "Cell type enhanced" "Detected in many" "Bergmann glia: 33.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA001625 Enhanced Supported Cytosol NA NA 37000000 "Cluster 30: Non-specific - DNA binding" "Cluster 22: Epididymis - Mixed function" "Cluster 44: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 10 Cytosol "HPA001625: " "unprognostic (3.47e-2)" "unprognostic (1.13e-2)" "unprognostic (1.69e-1)" "unprognostic (9.51e-3)" "unprognostic (2.11e-2)" "unprognostic (1.56e-1)" "unprognostic (2.42e-2)" "unprognostic (2.20e-1)" "unprognostic (3.74e-2)" "unprognostic (1.55e-1)" "validated prognostic favorable (4.97e-6)" "validated prognostic favorable (6.02e-4)" "unprognostic (2.29e-3)" "potential prognostic unfavorable (9.25e-4)" "unprognostic (1.47e-3)" "potential prognostic unfavorable (4.23e-4)" "unprognostic (4.52e-3)" "unprognostic (1.93e-1)" "unprognostic (3.31e-2)" "unprognostic (2.18e-1)" "unprognostic (1.11e-1)" "unprognostic (3.59e-3)" "unprognostic (2.33e-1)" "unprognostic (1.66e-1)" "unprognostic (1.33e-1)" "unprognostic (2.65e-2)" "unprognostic (9.17e-3)" "unprognostic (4.56e-1)" "unprognostic (2.04e-1)" "unprognostic (1.46e-1)" "unprognostic (3.69e-1)" PNPLA1 "dJ50J22.1, FLJ38755" ENSG00000180316 "Patatin like phospholipase domain containing 1" Q8N8W4 6 36243203-36313955 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism" Transferase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "skin 1: 22.5" "Group enriched" "Detected in many" 4 "Neutrophils: 89.1;Parietal cells: 38.9;Proximal tubule cells: 34.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 7 "basophil: 69.9;eosinophil: 18.9" "Lineage enriched" "Detected in many" 17 "granulocytes: 69.9" "Cancer enhanced" "Detected in single" "Leukemia: 1.2" "Adipose visceral - Neutrophils, Kidney - Proximal tubular cells, Lung - Neutrophils_2, Skin - Keratinocyte (other), Spleen - Neutrophils_2, Stomach - Parietal cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 37: Skin - Keratinization" "Cluster 48: Non-specific - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" "unprognostic (5.76e-3)" "unprognostic (1.50e-2)" "unprognostic (2.05e-1)" "unprognostic (9.06e-3)" "unprognostic (9.93e-2)" PNPLA2 "ATGL, desnutrin, FP17548, iPLA2zeta, TTS-2.2" ENSG00000177666 "Patatin like phospholipase domain containing 2" Q96AD5 11 818914-825573 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 487.2;breast: 357.1" "Cell type enhanced" "Detected in many" "Adipocytes: 370.0;Syncytiotrophoblasts: 216.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Minor Salivary Gland - Minor salivary glandular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055173, HPA062602, HPA075175" Approved Enhanced "Nucleoplasm,Lipid droplets" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 49: Hindbrain - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 89: Adipocytes - Lipid metabolism" 17 "Lipid droplets" Nucleoplasm "HPA055173: , HPA062602: , HPA075175: " "unprognostic (7.91e-2)" "unprognostic (3.52e-2)" "unprognostic (2.05e-1)" "unprognostic (1.79e-1)" "unprognostic (1.39e-1)" "unprognostic (1.72e-2)" "unprognostic (3.49e-2)" "unprognostic (3.26e-2)" "unprognostic (5.60e-2)" "unprognostic (2.40e-1)" "potential prognostic favorable (4.49e-4)" "unprognostic (3.19e-2)" "unprognostic (3.86e-2)" "unprognostic (5.51e-2)" "unprognostic (4.68e-3)" "unprognostic (7.32e-3)" "unprognostic (4.60e-1)" "unprognostic (2.80e-3)" "unprognostic (1.06e-1)" "unprognostic (1.16e-1)" "unprognostic (3.90e-1)" "unprognostic (9.27e-2)" "unprognostic (6.74e-2)" "unprognostic (1.20e-2)" "unprognostic (4.25e-2)" "unprognostic (1.37e-1)" "unprognostic (6.44e-2)" "unprognostic (2.10e-1)" "unprognostic (9.11e-2)" "unprognostic (7.18e-2)" "unprognostic (3.96e-2)" PNPLA3 "adiponutrin, ADPN, C22orf20, dJ796I17.1, FLJ22012, iPLA2epsilon" ENSG00000100344 "Patatin like phospholipase domain containing 3" Q9NST1 22 43923792-43964488 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Disease variant, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 29.0" "Cell type enhanced" "Detected in many" "Adipocytes: 115.5;Epididymal efferent duct ciliated cells: 53.3;Hepatocytes: 172.4;Proximal tubule cells: 63.4;Retinal bipolar cells: 80.6;Retinal pigment epithelial cells: 601.1;Rod photoreceptor cells: 62.6" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 29.9" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 6.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipocytes (Visceral), Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Spleen - Macrophages" "Region enhanced" "Detected in many" "cerebellum: 12.2" "Not detected" "Not detected" HPA058058 Approved Approved Nucleoli,Mitochondria,Cytosol NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 44: Non-specific - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" Nucleoli "Mitochondria, Cytosol" "HPA058058: " "unprognostic (3.51e-2)" "unprognostic (3.32e-2)" "potential prognostic favorable (9.43e-4)" "unprognostic (9.44e-2)" "unprognostic (6.69e-2)" "unprognostic (2.94e-1)" "unprognostic (2.59e-1)" "unprognostic (1.98e-2)" "unprognostic (1.92e-1)" "unprognostic (3.19e-2)" "unprognostic (8.39e-3)" "unprognostic (9.68e-2)" "unprognostic (2.19e-1)" "unprognostic (1.04e-1)" "unprognostic (8.57e-2)" "unprognostic (8.84e-2)" PNPLA4 "DXS1283E, GS2, iPLA2eta" ENSG00000006757 "Patatin like phospholipase domain containing 4" P41247 X 7898247-7927739 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 86.2;Esophageal suprabasal cells: 130.7;Oocytes: 101.3;Parietal cells: 106.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" HPA003656 Approved NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 76: Non-specific - Metabolism" "Cluster 46: Brainstem - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 5 "HPA003656: " "unprognostic (5.93e-2)" "unprognostic (1.36e-1)" "unprognostic (1.69e-1)" "unprognostic (8.98e-2)" "unprognostic (2.81e-2)" "unprognostic (1.23e-1)" "validated prognostic unfavorable (3.43e-4)" "validated prognostic unfavorable (1.66e-4)" "potential prognostic unfavorable (1.80e-4)" "unprognostic (4.54e-2)" "potential prognostic favorable (1.34e-12)" "unprognostic (4.02e-2)" "unprognostic (1.18e-1)" "unprognostic (5.09e-2)" "unprognostic (1.09e-1)" "unprognostic (1.44e-1)" "unprognostic (1.01e-1)" "unprognostic (4.86e-2)" "unprognostic (8.11e-3)" "unprognostic (9.52e-2)" "unprognostic (1.25e-1)" "unprognostic (4.63e-2)" "unprognostic (1.72e-1)" "unprognostic (1.52e-1)" "potential prognostic favorable (7.34e-4)" "unprognostic (7.54e-2)" "unprognostic (3.03e-1)" "unprognostic (4.07e-2)" "unprognostic (3.13e-2)" "unprognostic (3.09e-2)" "unprognostic (9.60e-2)" PNPLA5 "dJ388M5.4, GS2L" ENSG00000100341 "Patatin like phospholipase domain containing 5" Q7Z6Z6 22 43879678-43892013 "Enzymes, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.6;epididymis: 1.6;skin 1: 2.9" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 1.5;Brain inhibitory neurons: 4.6;Epicardial cells: 2.3;Epididymal efferent duct absorptive cells: 3.8;Epididymal principal cells: 11.4;Lactotrophs: 3.1;Late spermatids: 1.9;Pancreatic acinar cells: 2.3;Retinal pigment epithelial cells: 4.3;Somatotrophs: 8.1" "Cell type enhanced" "Detected in many" "medium spiny neuron: 8.1" "Cancer enhanced" "Detected in single" "Thyroid Carcinoma (TCGA): 1.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Sebaceous gland cells" "Not detected" "Not detected" "HPA050409, HPA054211" Uncertain Approved "Mid piece,Annulus" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 61: BICR 18 - Protein kinases" "Cluster 35: Neurons - Synaptic function & neurogenesis" 19 "Mid piece, Annulus" "HPA050409: , HPA054211: " "unprognostic (4.81e-2)" PNPLA6 "iPLA2delta, NTE, SPG39, sws" ENSG00000032444 "Patatin like phospholipase domain containing 6" Q8IY17 19 7534004-7561764 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease variant, Dwarfism, Hereditary spastic paraplegia, Hypogonadotropic hypogonadism, Intellectual disability, Neurodegeneration, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Kupffer cells: 123.0;Late primary spermatocytes: 108.8;Late spermatids: 192.9;Oocytes: 96.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007522, HPA064773" Uncertain Approved "Endoplasmic reticulum,Cytosol" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 67: Testis - Mixed function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 5 "Endoplasmic reticulum, Cytosol" "HPA007522: , HPA064773: " "unprognostic (2.76e-2)" "unprognostic (2.50e-1)" "unprognostic (1.89e-3)" "unprognostic (9.73e-3)" "unprognostic (8.59e-2)" "unprognostic (6.31e-2)" "unprognostic (3.76e-1)" "unprognostic (3.51e-1)" "potential prognostic favorable (7.06e-4)" "unprognostic (9.03e-3)" "unprognostic (2.16e-3)" "unprognostic (3.19e-2)" "potential prognostic favorable (5.10e-5)" "unprognostic (1.29e-2)" "unprognostic (4.97e-2)" "unprognostic (1.74e-2)" "unprognostic (6.51e-2)" "unprognostic (1.26e-2)" "unprognostic (3.62e-1)" "unprognostic (5.19e-2)" "unprognostic (3.41e-1)" "potential prognostic favorable (1.52e-4)" "unprognostic (2.17e-3)" "unprognostic (1.93e-1)" "unprognostic (1.21e-1)" "unprognostic (4.97e-3)" "unprognostic (1.14e-2)" "unprognostic (2.21e-2)" "unprognostic (9.03e-2)" "unprognostic (1.55e-1)" "unprognostic (7.08e-2)" PNPLA7 "C9orf111, FLJ31318, FLJ43070, FLJ44279, NTE-R1, NTEL1, RP11-48C7.2" ENSG00000130653 "Patatin like phospholipase domain containing 7" Q6ZV29 9 137459952-137550402 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 82.9;Myonuclei: 98.2;Prostatic glandular cells: 116.4;Rod photoreceptor cells: 86.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 23.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 1.0;T-reg: 1.2" "Group enriched" "Detected in many" 4 "B-cells: 1.0;T-cells: 1.2" "Cancer enhanced" "Detected in some" "prostate cancer: 5.4" "Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009130 Uncertain Uncertain "Centriolar satellite,Cytosol" NA NA "Cluster 18: Non-specific - Translation" "Cluster 24: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 7: Non-specific - Transcription" Cytosol "Centriolar satellite" "HPA009130: " "unprognostic (7.35e-2)" "unprognostic (4.04e-1)" "unprognostic (1.91e-3)" "unprognostic (1.51e-1)" "unprognostic (7.54e-2)" "unprognostic (2.89e-1)" "potential prognostic favorable (1.13e-5)" "unprognostic (3.68e-2)" "unprognostic (1.75e-3)" "potential prognostic favorable (1.29e-11)" "unprognostic (4.16e-3)" "unprognostic (2.86e-3)" "potential prognostic favorable (1.09e-5)" "unprognostic (1.32e-2)" "unprognostic (1.92e-1)" "unprognostic (6.67e-3)" "unprognostic (1.10e-1)" "unprognostic (1.85e-3)" "unprognostic (9.08e-2)" "unprognostic (2.20e-1)" "unprognostic (4.77e-2)" "unprognostic (9.85e-2)" "unprognostic (2.42e-1)" "unprognostic (1.03e-1)" "unprognostic (7.85e-3)" PNPLA8 "IPLA2-2, IPLA2G, iPLA2gamma" ENSG00000135241 "Patatin like phospholipase domain containing 8" Q9NP80 7 108470417-108569666 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial glandular cells: 530.5;monocytes: 515.5;Neutrophils: 1502.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020083 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 39: Non-specific - Transcription" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 1 "Nucleoplasm, Cytosol" "Golgi apparatus" "HPA020083: " "unprognostic (1.40e-2)" "unprognostic (3.18e-2)" "potential prognostic unfavorable (9.54e-4)" "unprognostic (2.35e-1)" "unprognostic (2.01e-1)" "unprognostic (2.38e-1)" "unprognostic (4.22e-1)" "unprognostic (1.16e-1)" "unprognostic (1.13e-1)" "unprognostic (1.30e-2)" "potential prognostic favorable (1.34e-7)" "unprognostic (5.96e-3)" "unprognostic (6.82e-2)" "unprognostic (4.68e-2)" "unprognostic (5.75e-2)" "unprognostic (1.38e-1)" "unprognostic (3.61e-1)" "unprognostic (1.67e-1)" "unprognostic (2.19e-1)" "unprognostic (3.55e-2)" "unprognostic (3.14e-2)" "unprognostic (7.10e-2)" "unprognostic (1.45e-2)" "unprognostic (1.09e-1)" "unprognostic (3.00e-1)" "unprognostic (2.98e-1)" "unprognostic (3.26e-2)" "unprognostic (2.84e-2)" "unprognostic (3.59e-1)" "unprognostic (1.99e-2)" "unprognostic (9.29e-2)" PNPO PDXPO ENSG00000108439 "Pyridoxamine 5'-phosphate oxidase" Q9NVS9 17 47941506-47949308 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Pyridoxine biosynthesis" Oxidoreductase "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 82.9" "Cell type enhanced" "Detected in many" "Ependymal cells: 11.0;Tuft cells: 11.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Pituitary gland - Undifferentiated cells (Pituitary gland), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023204, HPA027776" Enhanced Approved Nucleoplasm,Cytosol NA NA 410000 "Cluster 33: Non-specific - ATP binding" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 27: Breast cancer - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" 3 "Nucleoplasm, Cytosol" "HPA023204: , HPA027776: " "unprognostic (1.82e-2)" "unprognostic (2.99e-2)" "unprognostic (3.82e-2)" "unprognostic (2.22e-1)" "unprognostic (9.04e-2)" "unprognostic (1.05e-2)" "unprognostic (3.14e-1)" "unprognostic (1.42e-1)" "unprognostic (1.16e-1)" "unprognostic (1.58e-1)" "potential prognostic favorable (4.32e-5)" "unprognostic (1.44e-1)" "unprognostic (1.56e-1)" "unprognostic (2.76e-3)" "unprognostic (5.96e-2)" "unprognostic (2.43e-1)" "unprognostic (3.16e-2)" "unprognostic (1.46e-1)" "unprognostic (1.53e-1)" "unprognostic (1.58e-1)" "unprognostic (1.37e-2)" "unprognostic (8.92e-2)" "unprognostic (1.82e-1)" "unprognostic (3.35e-2)" "unprognostic (2.12e-2)" "unprognostic (3.86e-3)" "unprognostic (1.20e-1)" "unprognostic (2.44e-2)" "unprognostic (4.83e-2)" "unprognostic (2.26e-1)" "unprognostic (2.67e-1)" PNPT1 "DFNB70, old-35, OLD35, PNPase" ENSG00000138035 "Polyribonucleotide nucleotidyltransferase 1" Q8TCS8 2 55634061-55693863 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "mRNA processing, Transport" "Exonuclease, Hydrolase, Nuclease, Nucleotidyltransferase, RNA-binding, Transferase" "Deafness, Disease variant, Neurodegeneration, Non-syndromic deafness, Primary mitochondrial disease, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033424, HPA034602, HPA034603" Supported Supported Mitochondria,Cytosol NA NA 4600 "Cluster 21: Neutrophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 61: BICR 18 - Protein kinases" "Cluster 17: Non-specific - RNA processing" 36 Mitochondria Cytosol "CAB033424: , HPA034602: , HPA034603: " "unprognostic (1.49e-2)" "unprognostic (3.25e-2)" "unprognostic (2.40e-1)" "unprognostic (3.67e-1)" "unprognostic (2.29e-2)" "unprognostic (2.03e-1)" "unprognostic (2.58e-1)" "unprognostic (9.91e-3)" "unprognostic (6.20e-2)" "unprognostic (1.28e-1)" "unprognostic (3.06e-2)" "unprognostic (6.57e-2)" "unprognostic (1.64e-2)" "unprognostic (3.77e-3)" "potential prognostic unfavorable (2.00e-5)" "unprognostic (2.05e-1)" "unprognostic (3.08e-1)" "unprognostic (3.75e-1)" "unprognostic (1.80e-3)" "unprognostic (1.08e-1)" "unprognostic (7.69e-2)" "unprognostic (2.39e-1)" "unprognostic (2.67e-3)" "unprognostic (9.24e-2)" "unprognostic (1.82e-1)" "unprognostic (3.60e-2)" "unprognostic (2.39e-2)" "unprognostic (2.57e-1)" "unprognostic (2.89e-2)" "unprognostic (3.98e-1)" "unprognostic (5.85e-2)" PNRC1 "B4-2, PROL2, PRR2" ENSG00000146278 "Proline rich nuclear receptor coactivator 1" Q12796 6 89080751-89085160 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epididymal basal cells: 1231.3;monocytes: 1176.7;Neutrophils: 2907.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Neutrophils, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029839, HPA066513" Approved Approved Nucleoplasm,Nucleoli NA Yes "Cluster 21: Neutrophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 25: Non-specific - Ribosome" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 3 "Nucleoplasm, Nucleoli" "HPA029839: , HPA066513: " "unprognostic (1.03e-1)" "unprognostic (1.66e-1)" "unprognostic (8.70e-2)" "unprognostic (1.16e-2)" "unprognostic (1.71e-2)" "unprognostic (1.48e-1)" "unprognostic (1.41e-1)" "unprognostic (3.92e-2)" "unprognostic (4.65e-2)" "unprognostic (1.37e-2)" "validated prognostic favorable (1.07e-4)" "validated prognostic favorable (5.16e-6)" "potential prognostic unfavorable (5.74e-4)" "unprognostic (9.22e-2)" "unprognostic (2.77e-1)" "unprognostic (5.13e-2)" "unprognostic (4.27e-1)" "unprognostic (1.08e-1)" "unprognostic (1.00e-1)" "unprognostic (9.15e-2)" "unprognostic (1.47e-1)" "unprognostic (3.76e-1)" "unprognostic (3.93e-2)" "unprognostic (3.60e-1)" "unprognostic (5.03e-2)" "unprognostic (1.36e-1)" "unprognostic (2.50e-1)" "unprognostic (2.61e-3)" "unprognostic (1.68e-1)" "unprognostic (2.46e-1)" "unprognostic (6.10e-2)" PNRC2 ENSG00000189266 "Proline rich nuclear receptor coactivator 2" Q9NPJ4 1 23956839-23963462 "Predicted intracellular proteins" "Nonsense-mediated mRNA decay, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal basal cells: 330.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027820, HPA045837" Uncertain Supported "Nucleoplasm,Golgi apparatus" No No "Cluster 32: Basophils - Transcription" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 37: Non-specific - mRNA processing" "Cluster 103: Non-specific - Basic cellular processes" 8 Nucleoplasm "Golgi apparatus" "HPA027820: , HPA045837: " "unprognostic (3.58e-2)" "unprognostic (2.63e-2)" "unprognostic (1.44e-1)" "unprognostic (3.16e-2)" "unprognostic (5.29e-2)" "unprognostic (2.41e-1)" "unprognostic (2.60e-1)" "unprognostic (3.65e-3)" "unprognostic (1.04e-2)" "unprognostic (4.94e-2)" "validated prognostic favorable (2.22e-6)" "validated prognostic favorable (9.49e-5)" "unprognostic (2.52e-1)" "potential prognostic unfavorable (1.32e-4)" "unprognostic (4.30e-3)" "unprognostic (2.49e-2)" "unprognostic (6.74e-2)" "unprognostic (1.12e-1)" "unprognostic (1.58e-2)" "unprognostic (1.06e-1)" "unprognostic (1.34e-1)" "unprognostic (7.68e-2)" "unprognostic (4.08e-2)" "potential prognostic unfavorable (2.63e-4)" "unprognostic (4.38e-2)" "unprognostic (3.29e-2)" "unprognostic (2.40e-2)" "unprognostic (1.25e-1)" "unprognostic (1.36e-1)" "unprognostic (2.30e-1)" "unprognostic (1.10e-1)" POC1A "DKFZP434C245, WDR51A" ENSG00000164087 "POC1 centriolar protein A" Q8NBT0 3 52075226-52154690 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Dwarfism, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 11.9;testis: 16.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 26.9;Differentiating spermatogonia: 30.0;Early primary spermatocytes: 26.8;Early spermatids: 54.2;Erythrocyte progenitors: 40.8;Extravillous trophoblasts: 39.2;Late primary spermatocytes: 66.0;Late spermatids: 116.4;Megakaryocytes: 37.1;Migrating cytotrophoblasts: 33.9;Monocyte progenitors: 37.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040600 Approved Supported "Flagellar centriole,Mid piece,Principal piece" NA Yes "Cluster 33: Non-specific - ATP binding" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 53: Neurons - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Cell proliferation" 31 "Flagellar centriole" "Mid piece, Principal piece" "HPA040600: " "unprognostic (2.80e-2)" "unprognostic (1.42e-1)" "unprognostic (1.62e-1)" "unprognostic (1.90e-1)" "unprognostic (1.91e-2)" "unprognostic (1.51e-1)" "unprognostic (1.06e-1)" "unprognostic (6.17e-2)" "unprognostic (2.15e-1)" "potential prognostic unfavorable (3.27e-6)" "potential prognostic unfavorable (4.05e-6)" "unprognostic (2.09e-3)" "potential prognostic unfavorable (8.65e-4)" "validated prognostic unfavorable (8.40e-5)" "validated prognostic unfavorable (3.33e-7)" "validated prognostic unfavorable (1.23e-4)" "validated prognostic unfavorable (1.46e-4)" "unprognostic (2.16e-2)" "unprognostic (2.65e-1)" "unprognostic (2.45e-2)" "unprognostic (2.39e-2)" "potential prognostic unfavorable (2.93e-4)" "unprognostic (8.94e-3)" "unprognostic (2.18e-2)" "unprognostic (1.24e-2)" "unprognostic (7.90e-2)" "potential prognostic unfavorable (8.29e-4)" "unprognostic (1.06e-2)" "unprognostic (3.53e-1)" "unprognostic (1.78e-1)" "unprognostic (9.60e-2)" POC1B "FLJ14923, TUWD12, WDR51B" ENSG00000139323 "POC1 centriolar protein B" Q8TC44 12 89419718-89526047 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 237.2;Late spermatids: 168.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038841 Uncertain "Nucleoplasm,Cytosol,Flagellar centriole" NA NA "Cluster 32: Basophils - Transcription" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 51: Secretory epithelial cells - Mixed function" 28 "Cytosol, Flagellar centriole" Nucleoplasm "HPA038841: " "unprognostic (4.92e-2)" "unprognostic (2.20e-2)" "unprognostic (3.02e-1)" "unprognostic (3.98e-2)" "unprognostic (1.12e-1)" "unprognostic (1.06e-1)" "unprognostic (5.41e-3)" "unprognostic (1.69e-1)" "unprognostic (2.31e-1)" "unprognostic (3.04e-2)" "potential prognostic favorable (9.13e-10)" "unprognostic (4.35e-3)" "unprognostic (1.31e-1)" "unprognostic (4.59e-2)" "unprognostic (1.18e-1)" "unprognostic (9.04e-3)" "unprognostic (1.78e-1)" "unprognostic (9.11e-2)" "unprognostic (2.04e-1)" "unprognostic (3.60e-1)" "unprognostic (1.34e-2)" "unprognostic (3.82e-2)" "unprognostic (1.92e-1)" "unprognostic (6.09e-2)" "unprognostic (6.36e-3)" "unprognostic (7.46e-2)" "unprognostic (6.55e-2)" "unprognostic (1.68e-1)" "unprognostic (8.77e-2)" "unprognostic (6.82e-2)" "unprognostic (8.33e-3)" POC1B-GALNT4 ENSG00000259075 "POC1B-GALNT4 readthrough" 12 89519408-89526262 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.9;Endometrial glandular cells: 1.7;Endometrial luminal cells: 1.3;Epicardial cells: 6.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" HPA076116 Approved "Golgi apparatus" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" "Golgi apparatus" "HPA076116: " "unprognostic (9.15e-2)" "unprognostic (9.26e-2)" "unprognostic (1.22e-1)" "unprognostic (2.14e-1)" "unprognostic (3.19e-2)" "unprognostic (1.25e-1)" "unprognostic (5.23e-2)" "unprognostic (2.16e-1)" "unprognostic (7.20e-2)" "unprognostic (2.06e-1)" "unprognostic (2.32e-1)" "unprognostic (5.35e-2)" "unprognostic (1.45e-3)" "unprognostic (9.14e-2)" "unprognostic (3.07e-3)" "unprognostic (1.94e-2)" "unprognostic (4.27e-2)" "unprognostic (2.32e-2)" POC5 "C5orf37, FLJ35779, hPOC5, MGC120442, MGC120443, MGC120444" ENSG00000152359 "POC5 centriolar protein" Q8NA72 5 75674124-75717448 "Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 74.7;Late primary spermatocytes: 151.5;Rod photoreceptor cells: 100.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037510 Approved NA Yes "Cluster 5: Non-specific - Cell proliferation" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 79: Photoreceptor cells - Phototransduction" 20 "HPA037510: " "unprognostic (1.37e-2)" "unprognostic (3.63e-2)" "unprognostic (2.11e-2)" "unprognostic (6.58e-2)" "unprognostic (7.08e-2)" "unprognostic (8.91e-2)" "unprognostic (2.30e-1)" "unprognostic (9.83e-3)" "unprognostic (3.75e-2)" "unprognostic (3.35e-3)" "unprognostic (4.40e-2)" "unprognostic (1.61e-1)" "unprognostic (1.77e-1)" "potential prognostic unfavorable (3.32e-12)" "unprognostic (2.79e-1)" "unprognostic (9.68e-2)" "unprognostic (2.68e-3)" "unprognostic (3.56e-2)" "unprognostic (5.65e-2)" "unprognostic (1.39e-1)" "unprognostic (1.15e-2)" "unprognostic (2.11e-1)" "unprognostic (7.76e-3)" "unprognostic (3.47e-2)" "unprognostic (2.61e-1)" "unprognostic (1.34e-2)" "unprognostic (1.50e-1)" "unprognostic (2.51e-1)" "unprognostic (1.64e-1)" "unprognostic (2.71e-1)" "unprognostic (3.62e-1)" PODN "MGC24995, PCAN, PODOCAN, SLRR5A" ENSG00000174348 Podocan Q7Z5L7 1 53062052-53085501 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 54.9;Fibro-adipogenic progenitors: 170.8;Fibroblasts: 244.0;Hepatic stellate cells: 96.8;Leydig cells: 371.4;Mesothelial cells: 62.1;Ovarian stromal cells: 81.6;Peritubular myoid cells: 326.0;Pituicytes/FSCs: 77.6" "Cell type enhanced" "Detected in many" "endothelial cell: 38.3;fibroblast: 55.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "gdT-cell: 5.1;memory CD8 T-cell: 1.4;naive CD8 T-cell: 1.6" "Lineage enriched" "Detected in single" 52 "T-cells: 5.1" "Cancer enhanced" "Detected in some" "Sarcoma: 3.2" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblasts_2, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblasts_2, Spleen - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" "No annotated function" NA NA 8200000 "Cluster 24: Non-specific - Transcription" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 19: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" "potential prognostic favorable (7.87e-4)" "unprognostic (8.53e-2)" "unprognostic (1.99e-1)" "unprognostic (8.95e-2)" "unprognostic (7.37e-3)" "unprognostic (1.24e-1)" "unprognostic (1.15e-1)" "unprognostic (1.29e-1)" "unprognostic (4.73e-2)" "unprognostic (3.59e-3)" "unprognostic (1.70e-1)" "unprognostic (1.12e-1)" "unprognostic (1.90e-3)" "unprognostic (2.01e-1)" "unprognostic (1.68e-3)" "unprognostic (1.16e-1)" "unprognostic (4.47e-1)" "unprognostic (6.38e-3)" "unprognostic (3.64e-1)" "unprognostic (2.67e-3)" "potential prognostic unfavorable (8.39e-4)" "unprognostic (3.94e-1)" "unprognostic (2.64e-2)" "unprognostic (1.88e-2)" "unprognostic (8.29e-2)" "unprognostic (2.53e-2)" "unprognostic (1.18e-1)" "unprognostic (9.31e-3)" "unprognostic (2.71e-1)" "unprognostic (7.13e-2)" "unprognostic (4.40e-2)" PODNL1 "FLJ23447, SLRR5B" ENSG00000132000 "Podocan like 1" Q6PEZ8 19 13931187-13953392 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 12.7" "Cell type enhanced" "Detected in some" "Astrocytes: 2.9;Bergmann glia: 1.5;Brain excitatory neurons: 2.3;Brain inhibitory neurons: 1.7;Ependymal cells: 9.2;Other brain neurons: 5.7;Papillary tip epithelial cells: 1.6;Peritubular myoid cells: 1.7" "Cell type enhanced" "Detected in many" "ependymal cell: 10.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 7.8;Rhabdoid: 8.0" "Testis - Peritubular cells, Thyroid gland - Fibroblasts" "Not detected" "Not detected" "Region enriched" "Detected in some" 11 "spinal cord: 23.2" HPA042807 Approved "Secreted - unknown location" "No annotated function" NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 34: Ciliated cells - Cilia assembly & function" "HPA042807: " "unprognostic (4.32e-1)" "unprognostic (1.72e-1)" "unprognostic (2.99e-1)" "unprognostic (1.82e-1)" "unprognostic (7.71e-3)" "unprognostic (8.61e-3)" "potential prognostic unfavorable (4.88e-6)" "unprognostic (2.49e-1)" "potential prognostic unfavorable (8.58e-8)" "unprognostic (7.95e-3)" "potential prognostic unfavorable (3.35e-5)" "unprognostic (1.43e-1)" "unprognostic (1.27e-3)" "unprognostic (3.14e-2)" "unprognostic (9.66e-3)" "unprognostic (1.78e-3)" "unprognostic (4.61e-3)" "unprognostic (5.47e-2)" "unprognostic (7.98e-2)" "unprognostic (3.05e-1)" "unprognostic (2.61e-1)" "unprognostic (1.83e-2)" "unprognostic (1.55e-1)" "unprognostic (9.15e-3)" "unprognostic (7.55e-2)" "unprognostic (4.67e-2)" "unprognostic (1.06e-2)" PODXL "gp135, Gp200, PC, PCLP, PDX, PODXL1" ENSG00000128567 "Podocalyxin like" O00592 7 131500262-131558217 "Plasma proteins, Predicted membrane proteins, Transporters" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 130.6" "Cell type enriched" "Detected in many" 6 "Podocytes: 2497.9" "Cell type enriched" "Detected in all" 8 "endothelial cell: 580.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in all" 5 "testis cancer: 590.4" "Adrenal gland - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Podocytes, Liver - Vascular endothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002110, CAB016169, HPA045507, CAB062558, CAB068219, CAB068220" Enhanced Approved "Nucleoli,Endoplasmic reticulum,Vesicles,Plasma membrane,Centriolar satellite" NA NA 9400000 "Cluster 72: Kidney - Transmembrane transport" "Cluster 47: Endothelial cells - Vasculature" "Cluster 34: Testis cancer - Unknown function" "Cluster 57: Podocytes - Glomerular filtration" 10 "Endoplasmic reticulum, Plasma membrane" "Nucleoli, Vesicles, Centriolar satellite" "CAB016169: , CAB062558: , CAB068219: , CAB068220: , HPA002110: , HPA045507: " "unprognostic (6.59e-3)" "unprognostic (1.12e-1)" "unprognostic (9.25e-3)" "unprognostic (1.25e-1)" "unprognostic (1.59e-1)" "unprognostic (3.06e-2)" "unprognostic (4.54e-2)" "unprognostic (7.88e-3)" "unprognostic (6.86e-2)" "unprognostic (4.48e-1)" "validated prognostic favorable (2.81e-13)" "validated prognostic favorable (1.16e-4)" "unprognostic (1.43e-3)" "unprognostic (1.34e-2)" "unprognostic (3.38e-2)" "unprognostic (3.27e-1)" "unprognostic (1.52e-2)" "unprognostic (2.86e-2)" "unprognostic (8.87e-2)" "unprognostic (9.12e-2)" "unprognostic (1.73e-1)" "potential prognostic unfavorable (2.77e-4)" "unprognostic (9.45e-3)" "unprognostic (1.61e-1)" "unprognostic (3.08e-1)" "unprognostic (1.02e-1)" "potential prognostic unfavorable (5.09e-4)" "unprognostic (1.42e-1)" "unprognostic (4.73e-2)" "unprognostic (2.02e-2)" "unprognostic (7.02e-2)" PODXL2 "endoglycan, PODLX2" ENSG00000114631 "Podocalyxin like 2" Q9NZ53 3 127629185-127672802 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 98.6;pituitary gland: 56.0" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 73.2;Differentiating spermatogonia: 69.5;Late primary spermatocytes: 68.3;Late spermatids: 267.3;Other brain neurons: 98.3;Retinal bipolar cells: 67.7;Undifferentiated spermatogonia: 121.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Testis - Spermatogonia, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB024934, HPA042265" Approved Approved "Golgi apparatus,Vesicles" NA NA 67000 "Cluster 27: Cerebellum - Synaptic function" "Cluster 1: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 98: Neurons - Neurotransmission & signaling" 1 "Golgi apparatus" Vesicles "CAB024934: , HPA042265: " "unprognostic (1.71e-2)" "unprognostic (4.83e-2)" "unprognostic (3.29e-2)" "unprognostic (2.34e-1)" "unprognostic (1.87e-1)" "potential prognostic unfavorable (1.87e-4)" "unprognostic (1.31e-1)" "unprognostic (1.40e-3)" "unprognostic (1.04e-2)" "unprognostic (7.68e-2)" "potential prognostic unfavorable (4.91e-4)" "unprognostic (3.42e-2)" "unprognostic (1.39e-2)" "unprognostic (2.38e-3)" "unprognostic (2.24e-1)" "unprognostic (1.70e-1)" "unprognostic (5.40e-2)" "unprognostic (5.76e-2)" "unprognostic (3.38e-3)" "unprognostic (1.57e-1)" "unprognostic (1.76e-1)" "unprognostic (1.16e-3)" "unprognostic (1.76e-3)" "unprognostic (3.39e-1)" "unprognostic (3.19e-1)" "unprognostic (6.01e-2)" "unprognostic (3.23e-1)" "unprognostic (6.72e-2)" "unprognostic (1.03e-2)" "unprognostic (2.14e-2)" "unprognostic (2.27e-1)" POF1B "FLJ22792, POF" ENSG00000124429 "POF1B actin binding protein" Q8WVV4 X 85277396-85379717 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Disease variant, Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 50.9;skin 1: 118.4" "Cell type enhanced" "Detected in many" "Colonocytes: 340.5;Enteric stem cells: 159.6;Enteric transient amplifying cells: 192.4;Enterocytes: 226.8;Esophageal apical cells: 373.5;Foveolar cells: 171.6;Goblet cells: 243.5;Ocular epithelial cells: 190.8;Prostatic club cells: 115.8;Prostatic hillock cells: 141.7;Suprabasal keratinocytes: 135.2;Tuft cells: 172.9;Urothelial cells: 218.2" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 65.6;Rectum Adenocarcinoma (TCGA): 71.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 2.9;naive B-cell: 2.2" "Lineage enriched" "Detected in single" 7 "B-cells: 2.9" "Cancer enhanced" "Detected in many" "colorectal cancer: 60.1;Gastric cancer: 41.4" "Adipose subcutaneous - Smooth muscle cells, Colon - Colon enterocytes, Liver - Cholangiocytes, Spleen - Endothelial cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA002033, HPA050027" Approved Supported "Nucleoplasm,Golgi apparatus" NA NA 970000 "Cluster 14: Non-specific - Unknown function" "Cluster 58: Skin - Keratinization" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 1 "Golgi apparatus" Nucleoplasm "HPA002033: , HPA050027: " "unprognostic (2.17e-2)" "unprognostic (2.11e-1)" "unprognostic (2.13e-1)" "unprognostic (1.31e-1)" "unprognostic (1.54e-2)" "unprognostic (1.69e-2)" "unprognostic (1.14e-1)" "unprognostic (8.62e-2)" "unprognostic (3.78e-1)" "unprognostic (1.30e-2)" "potential prognostic unfavorable (7.56e-5)" "unprognostic (7.00e-2)" "unprognostic (1.61e-1)" "unprognostic (4.16e-2)" "unprognostic (5.03e-2)" "unprognostic (1.94e-1)" "unprognostic (4.59e-2)" "unprognostic (2.78e-1)" "unprognostic (3.55e-3)" "potential prognostic favorable (8.87e-4)" "unprognostic (1.71e-1)" "unprognostic (7.89e-3)" "unprognostic (1.21e-1)" "unprognostic (1.25e-1)" "unprognostic (9.43e-3)" "unprognostic (1.58e-1)" "unprognostic (7.53e-2)" POFUT1 "FUT12, KIAA0180, O-Fuc-T, O-FUT" ENSG00000101346 "Protein O-fucosyltransferase 1" Q9H488 20 32207855-32238658 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Fucose metabolism, Notch signaling pathway" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 66.6;Gastric progenitor cells: 65.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 18.3" "Lineage enriched" "Detected in all" 5 "monocytes: 18.3" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054519, HPA059935" Approved Approved Centrosome "Intracellular and membrane" Enzyme NA NA 68000 "Cluster 40: Monocytes - Innate immune response" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 1: Enterocytes - Absorption and Digestion" 3 Centrosome "HPA054519: , HPA059935: " "unprognostic (1.04e-1)" "unprognostic (6.38e-2)" "unprognostic (1.26e-3)" "unprognostic (7.56e-3)" "unprognostic (4.65e-2)" "unprognostic (5.70e-2)" "unprognostic (9.04e-2)" "potential prognostic unfavorable (1.63e-4)" "unprognostic (2.48e-1)" "unprognostic (1.01e-1)" "unprognostic (1.04e-2)" "unprognostic (2.01e-1)" "unprognostic (3.38e-1)" "unprognostic (1.80e-1)" "unprognostic (1.22e-1)" "unprognostic (9.87e-3)" "unprognostic (5.87e-2)" "unprognostic (8.29e-2)" "unprognostic (6.58e-2)" "unprognostic (4.68e-2)" "potential prognostic unfavorable (1.47e-5)" "unprognostic (6.64e-2)" "unprognostic (2.75e-1)" "unprognostic (8.00e-2)" "unprognostic (2.37e-3)" "unprognostic (4.19e-2)" "unprognostic (2.61e-1)" "unprognostic (7.18e-2)" "unprognostic (3.53e-1)" "unprognostic (1.84e-2)" "unprognostic (3.87e-1)" POFUT2 "C21orf80, FUT13, KIAA0958" ENSG00000186866 "Protein O-fucosyltransferase 2" Q9Y2G5 21 45263928-45287898 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism, Fucose metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 77.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044297 Uncertain "Intracellular and membrane" Enzyme NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 20: Pituitary gland - Hormone signaling" "Cluster 44: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 29: Neutrophils - Innate immune cellular maintenance" "HPA044297: " "unprognostic (1.43e-2)" "unprognostic (2.83e-3)" "unprognostic (7.61e-2)" "unprognostic (1.75e-2)" "unprognostic (2.72e-3)" "unprognostic (1.38e-1)" "unprognostic (8.35e-3)" "potential prognostic unfavorable (6.40e-4)" "unprognostic (6.60e-2)" "unprognostic (2.13e-2)" "potential prognostic unfavorable (7.02e-6)" "unprognostic (5.01e-3)" "unprognostic (2.29e-1)" "potential prognostic unfavorable (1.79e-5)" "unprognostic (2.29e-1)" "unprognostic (7.74e-2)" "unprognostic (2.98e-2)" "unprognostic (1.69e-1)" "unprognostic (7.04e-2)" "unprognostic (1.16e-1)" "unprognostic (1.08e-1)" "unprognostic (4.10e-2)" "unprognostic (2.96e-2)" "unprognostic (1.54e-2)" "unprognostic (7.82e-2)" "unprognostic (2.57e-2)" "unprognostic (1.74e-1)" "unprognostic (1.58e-1)" "unprognostic (2.00e-1)" "unprognostic (4.14e-3)" "unprognostic (1.62e-1)" POGK "BASS2, KIAA15131, KRBOX2, LST003" ENSG00000143157 "Pogo transposable element derived with KRAB domain" Q9P215 1 166839447-166856359 "Predicted intracellular proteins" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 122.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007838, HPA031630, HPA075919" Approved Enhanced Nucleoplasm NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 9 Nucleoplasm "HPA007838: , HPA031630: , HPA075919: " "potential prognostic favorable (2.46e-5)" "unprognostic (6.75e-2)" "unprognostic (5.51e-2)" "unprognostic (2.26e-2)" "unprognostic (1.98e-1)" "unprognostic (6.20e-2)" "unprognostic (4.45e-2)" "potential prognostic favorable (6.07e-4)" "unprognostic (3.15e-1)" "unprognostic (3.35e-1)" "potential prognostic favorable (1.15e-4)" "unprognostic (1.78e-2)" "unprognostic (5.29e-3)" "potential prognostic unfavorable (3.33e-4)" "unprognostic (2.06e-2)" "unprognostic (1.01e-1)" "unprognostic (6.95e-2)" "unprognostic (4.64e-2)" "unprognostic (7.46e-2)" "unprognostic (3.46e-1)" "unprognostic (1.86e-2)" "unprognostic (5.66e-2)" "unprognostic (3.57e-1)" "unprognostic (7.33e-2)" "unprognostic (1.61e-2)" "unprognostic (8.95e-3)" "unprognostic (1.80e-2)" "unprognostic (1.81e-1)" "unprognostic (1.31e-1)" "unprognostic (3.88e-2)" "unprognostic (1.31e-1)" POGLUT1 "9630046K23Rik, C3orf9, hCLP46, KDELCL1, KTELC1, MDS010, MDSRP, MGC32995, Rumi" ENSG00000163389 "Protein O-glucosyltransferase 1" Q8NBL1 3 119468963-119494708 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Gastrulation "Developmental protein, Glycosyltransferase, Transferase" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "cDC: 92.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037855, HPA037856" Approved Supported "Endoplasmic reticulum" "Intracellular and membrane" "Developmental protein" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 82: Dendritic cells - Antigen presentation" 28 "Endoplasmic reticulum" "HPA037855: , HPA037856: " "unprognostic (1.38e-2)" "unprognostic (1.25e-1)" "unprognostic (8.56e-2)" "unprognostic (1.17e-1)" "unprognostic (5.15e-2)" "unprognostic (3.06e-1)" "unprognostic (8.96e-2)" "unprognostic (1.51e-3)" "unprognostic (1.20e-1)" "unprognostic (2.61e-1)" "unprognostic (6.25e-2)" "unprognostic (1.54e-1)" "unprognostic (1.61e-1)" "unprognostic (2.34e-1)" "unprognostic (2.19e-1)" "unprognostic (1.01e-1)" "unprognostic (1.73e-1)" "unprognostic (2.80e-2)" "unprognostic (1.27e-1)" "unprognostic (1.72e-1)" "unprognostic (6.91e-3)" "unprognostic (5.69e-2)" "unprognostic (1.13e-1)" "unprognostic (1.93e-1)" "unprognostic (7.43e-3)" "unprognostic (1.06e-1)" "unprognostic (3.57e-2)" "unprognostic (1.42e-1)" "unprognostic (1.39e-3)" "unprognostic (6.24e-2)" POGLUT2 "EP58, KDELC1, MGC5302" ENSG00000134901 "Protein O-glucosyltransferase 2" Q6UW63 13 102784281-102799040 "Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 19.2;Extravillous trophoblasts: 32.3;Hepatic stellate cells: 19.4;Peritubular myoid cells: 11.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 3.4" "Group enriched" "Detected in many" 5 "NK-cells: 3.4;T-cells: 2.2" "Cancer enhanced" "Detected in all" "Kidney cancer: 60.1" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020780, HPA043946, HPA064398" Approved Supported Nucleoplasm "Intracellular and membrane" Enzyme NA NA 56000 "Cluster 1: T-cells - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 108: Fibroblasts - ECM organization" 26 Nucleoplasm "CAB020780: , HPA043946: , HPA064398: " "unprognostic (2.37e-1)" "unprognostic (1.28e-2)" "unprognostic (1.03e-1)" "unprognostic (6.01e-3)" "unprognostic (4.49e-2)" "unprognostic (1.02e-1)" "unprognostic (3.42e-3)" "unprognostic (5.16e-3)" "unprognostic (5.53e-2)" "unprognostic (6.27e-3)" "unprognostic (2.74e-1)" "unprognostic (8.62e-2)" "unprognostic (1.75e-3)" "unprognostic (6.89e-3)" "potential prognostic unfavorable (4.11e-4)" "unprognostic (3.12e-2)" "unprognostic (1.79e-1)" "unprognostic (2.89e-2)" "unprognostic (4.69e-3)" "unprognostic (5.44e-2)" "unprognostic (8.45e-2)" "unprognostic (1.96e-3)" "unprognostic (2.26e-1)" "unprognostic (8.57e-2)" "unprognostic (2.90e-2)" "unprognostic (1.39e-2)" "unprognostic (1.53e-1)" "unprognostic (5.17e-2)" "unprognostic (1.04e-1)" POGLUT3 "KDELC2, MGC33424" ENSG00000178202 "Protein O-glucosyltransferase 3" Q7Z4H8 11 108472112-108498405 "Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 51.9;Respiratory deuterosomal cells: 98.5" "Cell type enhanced" "Detected in many" "ependymal cell: 34.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Adrenal gland - Fibroblasts, Breast - Fibroblasts, Kidney - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039315, HPA039817, HPA066134" Approved Approved Nucleoplasm,Vesicles "Intracellular and membrane" Enzyme NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 46: Brainstem - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 108: Fibroblasts - ECM organization" 14 Nucleoplasm Vesicles "HPA039315: , HPA039817: , HPA066134: " "unprognostic (5.77e-2)" "unprognostic (1.12e-1)" "unprognostic (1.09e-1)" "unprognostic (1.72e-1)" "unprognostic (2.67e-2)" "unprognostic (4.74e-3)" "potential prognostic unfavorable (3.27e-6)" "unprognostic (1.36e-2)" "unprognostic (1.12e-1)" "potential prognostic favorable (9.26e-5)" "unprognostic (7.19e-2)" "unprognostic (7.60e-3)" "potential prognostic unfavorable (2.22e-4)" "unprognostic (1.26e-3)" "unprognostic (1.58e-3)" "unprognostic (4.80e-2)" "unprognostic (2.18e-1)" "unprognostic (2.46e-1)" "unprognostic (3.53e-1)" "potential prognostic unfavorable (6.69e-4)" "unprognostic (1.58e-2)" "unprognostic (4.87e-2)" "unprognostic (3.85e-1)" "unprognostic (4.70e-2)" "unprognostic (1.87e-3)" "unprognostic (1.42e-2)" "unprognostic (1.55e-1)" "unprognostic (1.10e-1)" "unprognostic (4.42e-1)" POGZ "KIAA0461, ZNF280E, ZNF635" ENSG00000143442 "Pogo transposable element derived with ZNF domain" Q7Z3K3 1 151402724-151459494 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Cell cycle, Cell division, DNA damage, DNA recombination, DNA repair" DNA-binding "Autism spectrum disorder, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006800, HPA008781" Enhanced Supported "Nucleoplasm,Plasma membrane,Basal body,Cytosol" NA NA "Cluster 32: Basophils - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 45: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" 103 Nucleoplasm "Plasma membrane, Basal body, Cytosol" "HPA006800: , HPA008781: " "unprognostic (9.66e-3)" "unprognostic (5.39e-2)" "unprognostic (7.18e-2)" "unprognostic (1.09e-2)" "unprognostic (1.81e-1)" "unprognostic (1.52e-2)" "unprognostic (8.59e-2)" "unprognostic (1.08e-2)" "unprognostic (5.69e-3)" "unprognostic (1.83e-3)" "unprognostic (9.57e-3)" "unprognostic (2.11e-3)" "unprognostic (9.64e-2)" "unprognostic (6.34e-2)" "unprognostic (5.60e-3)" "unprognostic (9.34e-2)" "unprognostic (1.83e-2)" "unprognostic (1.48e-1)" "unprognostic (1.67e-2)" "unprognostic (8.11e-2)" "unprognostic (3.01e-2)" "unprognostic (5.26e-2)" "unprognostic (5.87e-3)" "unprognostic (1.66e-1)" "unprognostic (1.45e-1)" "unprognostic (6.59e-2)" "unprognostic (9.95e-2)" "unprognostic (3.06e-1)" "unprognostic (5.11e-2)" "unprognostic (1.03e-1)" "unprognostic (1.81e-2)" POLA1 "NSX, p180, POLA" ENSG00000101868 "DNA polymerase alpha 1, catalytic subunit" P09884 X 24693873-24996986 "Disease related genes, Enzymes, Essential proteins, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "DNA replication, Host-virus interaction" "DNA-binding, DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase" "Disease variant, Dwarfism, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 262.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002947, CAB012274" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 80: Thymus - Adaptive immune response" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 25 Nucleoplasm Cytosol "CAB012274: , HPA002947: " "unprognostic (6.67e-3)" "unprognostic (5.24e-2)" "unprognostic (5.59e-2)" "unprognostic (2.33e-1)" "unprognostic (2.73e-2)" "unprognostic (2.97e-1)" "unprognostic (2.06e-1)" "unprognostic (4.27e-2)" "unprognostic (1.13e-1)" "unprognostic (6.20e-2)" "potential prognostic favorable (1.89e-7)" "unprognostic (9.13e-3)" "unprognostic (1.69e-2)" "unprognostic (8.41e-3)" "potential prognostic unfavorable (8.21e-4)" "unprognostic (3.40e-2)" "unprognostic (4.85e-3)" "unprognostic (2.77e-2)" "unprognostic (2.21e-2)" "unprognostic (1.14e-1)" "unprognostic (1.19e-1)" "unprognostic (1.09e-3)" "unprognostic (2.31e-1)" "unprognostic (7.86e-2)" "unprognostic (1.97e-3)" "unprognostic (1.26e-2)" "unprognostic (2.47e-2)" "unprognostic (1.96e-1)" "unprognostic (2.21e-1)" "unprognostic (6.91e-2)" "unprognostic (1.26e-1)" POLA2 FLJ21662 ENSG00000014138 "DNA polymerase alpha 2, accessory subunit" Q14181 11 65261913-65305959 "Essential proteins, Metabolic proteins, Predicted intracellular proteins" "DNA replication" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 7.6;Brain inhibitory neurons: 5.8;Choroid plexus epithelial cells: 10.0;Distal convoluted tubule cells: 5.8;Ependymal cells: 6.5;Loop of henle epithelial cells: 7.3;Microglia: 22.7;Oligodendrocytes: 16.4;Papillary tip epithelial cells: 11.7;Podocytes: 44.9;Proximal tubule cells: 7.0;Renal collecting duct intercalated cells: 6.5;Renal collecting duct principal cells: 11.1;Renal connecting tubule cells: 6.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037570 Supported Supported "Nucleoplasm,Basal body,Cytosol" NA Yes "Cluster 13: Non-specific - Mitochondria" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 6: Non-specific - Immune response" "Cluster 24: Non-specific - Unknown function" "Cluster 102: Non-specific - Mixed function" 17 Nucleoplasm "Basal body, Cytosol" "HPA037570: " "unprognostic (2.96e-1)" "unprognostic (4.77e-2)" "unprognostic (1.49e-1)" "unprognostic (1.24e-1)" "unprognostic (1.09e-1)" "unprognostic (2.55e-1)" "unprognostic (2.50e-1)" "unprognostic (7.27e-2)" "unprognostic (6.71e-2)" "potential prognostic unfavorable (4.19e-4)" "unprognostic (8.95e-3)" "potential prognostic unfavorable (4.97e-4)" "unprognostic (5.17e-1)" "validated prognostic unfavorable (1.26e-7)" "validated prognostic unfavorable (7.86e-4)" "potential prognostic unfavorable (5.75e-4)" "unprognostic (4.18e-3)" "unprognostic (2.35e-2)" "unprognostic (1.55e-1)" "unprognostic (2.99e-2)" "unprognostic (9.04e-2)" "unprognostic (4.05e-2)" "unprognostic (4.06e-2)" "unprognostic (2.32e-1)" "unprognostic (2.38e-2)" "unprognostic (9.20e-2)" "unprognostic (3.59e-2)" "unprognostic (8.38e-3)" "unprognostic (1.97e-1)" "unprognostic (1.04e-1)" "unprognostic (3.49e-1)" POLB ENSG00000070501 "DNA polymerase beta" P06746 8 42338454-42371808 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, DNA synthesis" "DNA-binding, DNA-directed DNA polymerase, Lyase, Nucleotidyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 176.1" "Cell type enhanced" "Detected in many" "Early spermatids: 315.8;Late primary spermatocytes: 137.5;Late spermatids: 225.5;pDCs: 516.7" "Cell type enhanced" "Detected in all" "upper rhombic lip: 189.9" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 134.1" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011616, HPA049104, HPA069013, CAB080371" Enhanced Supported Vesicles,Cytosol NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 35: Non-specific - DNA binding" "Cluster 29: Non-specific - Unknown function" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 32 "Vesicles, Cytosol" "CAB011616: , CAB080371: , HPA049104: , HPA069013: " "unprognostic (6.63e-2)" "unprognostic (1.67e-2)" "unprognostic (9.63e-2)" "unprognostic (1.18e-1)" "unprognostic (1.75e-1)" "unprognostic (1.26e-1)" "unprognostic (4.21e-1)" "potential prognostic favorable (5.11e-4)" "unprognostic (4.14e-2)" "unprognostic (1.20e-2)" "unprognostic (5.68e-3)" "unprognostic (3.82e-2)" "potential prognostic unfavorable (3.99e-4)" "unprognostic (1.26e-1)" "unprognostic (2.29e-3)" "unprognostic (1.80e-2)" "unprognostic (1.38e-2)" "unprognostic (6.12e-3)" "unprognostic (2.24e-2)" "unprognostic (1.36e-1)" "unprognostic (1.61e-3)" "unprognostic (1.79e-2)" "unprognostic (3.06e-2)" "unprognostic (4.51e-1)" "unprognostic (1.62e-2)" "unprognostic (3.17e-2)" "unprognostic (6.44e-2)" "unprognostic (8.52e-2)" "unprognostic (3.97e-1)" "unprognostic (4.82e-2)" "unprognostic (4.01e-2)" POLD1 "CDC2, POLD" ENSG00000062822 "DNA polymerase delta 1, catalytic subunit" P28340 19 50384204-50418018 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA excision, DNA repair, DNA replication" "DNA-binding, DNA-directed DNA polymerase, Exonuclease, Hydrolase, Nuclease, Nucleotidyltransferase, Transferase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 30.9;Erythrocyte progenitors: 28.3;Tuft cells: 23.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004375, HPA046524" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 18: Non-specific - Translation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 6: Non-specific - Immune response" "Cluster 4: Non-specific - Transcription" "Cluster 27: Non-specific - Cell proliferation" 71 Nucleoplasm Cytosol "CAB004375: , HPA046524: " "unprognostic (1.22e-1)" "unprognostic (3.40e-1)" "unprognostic (5.17e-2)" "unprognostic (1.21e-1)" "unprognostic (1.54e-1)" "unprognostic (2.83e-1)" "unprognostic (2.11e-1)" "unprognostic (1.20e-1)" "unprognostic (3.67e-2)" "unprognostic (9.89e-2)" "potential prognostic unfavorable (4.80e-4)" "unprognostic (1.79e-2)" "unprognostic (1.04e-1)" "validated prognostic unfavorable (7.56e-6)" "validated prognostic unfavorable (9.11e-5)" "potential prognostic unfavorable (7.56e-5)" "unprognostic (5.06e-2)" "unprognostic (3.74e-2)" "unprognostic (5.50e-2)" "unprognostic (4.22e-1)" "unprognostic (3.54e-2)" "unprognostic (2.66e-1)" "unprognostic (1.50e-1)" "unprognostic (1.05e-2)" "unprognostic (9.25e-2)" "unprognostic (1.81e-3)" "unprognostic (1.43e-2)" "unprognostic (9.62e-3)" "unprognostic (6.93e-2)" "unprognostic (3.00e-1)" "unprognostic (5.89e-2)" POLD2 ENSG00000106628 "DNA polymerase delta 2, accessory subunit" P49005 7 44114631-44124358 "Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA excision, DNA repair, DNA replication" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 239.8;Esophageal suprabasal cells: 208.2;Late spermatids: 495.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026745 Approved Enhanced Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 70: Non-specific - Protein processing" "Cluster 19: Astrocytes - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 26 Nucleoplasm "HPA026745: " "unprognostic (8.36e-2)" "unprognostic (1.02e-1)" "unprognostic (6.05e-2)" "unprognostic (2.72e-2)" "unprognostic (4.54e-2)" "unprognostic (1.21e-1)" "unprognostic (1.47e-1)" "unprognostic (1.99e-1)" "potential prognostic unfavorable (1.90e-4)" "potential prognostic unfavorable (5.59e-5)" "unprognostic (1.55e-2)" "unprognostic (7.43e-2)" "unprognostic (1.11e-1)" "validated prognostic unfavorable (8.75e-6)" "validated prognostic unfavorable (1.15e-5)" "validated prognostic unfavorable (2.14e-5)" "validated prognostic unfavorable (7.08e-4)" "unprognostic (7.23e-2)" "unprognostic (1.11e-1)" "unprognostic (9.37e-3)" "unprognostic (1.50e-1)" "unprognostic (1.80e-1)" "unprognostic (1.31e-1)" "unprognostic (2.29e-2)" "unprognostic (2.61e-1)" "unprognostic (1.33e-1)" "unprognostic (1.90e-1)" "unprognostic (2.11e-1)" "unprognostic (3.95e-2)" "unprognostic (4.35e-2)" "unprognostic (1.11e-1)" POLD3 "KIAA0039, P66, P68, PPP1R128" ENSG00000077514 "DNA polymerase delta 3, accessory subunit" Q15054 11 74493851-74669117 "Essential proteins, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA excision, DNA repair, DNA replication" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" HPA058846 Enhanced Supported Nucleoplasm NA Yes "Cluster 7: Non-specific - Innate immune response" "Cluster 72: Kidney - Transmembrane transport" "Cluster 31: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 35 Nucleoplasm "HPA058846: " "unprognostic (5.51e-2)" "unprognostic (2.48e-1)" "unprognostic (3.50e-1)" "unprognostic (3.51e-1)" "unprognostic (5.99e-2)" "unprognostic (1.63e-1)" "unprognostic (3.32e-1)" "unprognostic (1.44e-1)" "unprognostic (2.62e-1)" "potential prognostic unfavorable (2.24e-4)" "potential prognostic favorable (7.07e-6)" "unprognostic (2.30e-1)" "unprognostic (2.40e-1)" "unprognostic (1.17e-3)" "unprognostic (8.06e-3)" "unprognostic (1.17e-3)" "unprognostic (5.83e-3)" "unprognostic (1.54e-1)" "unprognostic (3.80e-1)" "unprognostic (3.66e-2)" "unprognostic (2.64e-2)" "unprognostic (2.69e-2)" "unprognostic (3.30e-1)" "unprognostic (9.99e-2)" "unprognostic (2.18e-2)" "unprognostic (1.12e-1)" "unprognostic (3.35e-3)" "unprognostic (4.92e-3)" "unprognostic (3.85e-1)" "unprognostic (2.57e-1)" "unprognostic (6.05e-2)" POLD4 "p12, POLDS" ENSG00000175482 "DNA polymerase delta 4, accessory subunit" Q9HCU8 11 67350772-67356972 "Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA excision, DNA repair, DNA replication" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 198.2" "Cell type enhanced" "Detected in many" "Colonocytes: 386.2;Enteric transient amplifying cells: 104.7;Enterocytes: 359.5;Esophageal apical cells: 93.3;Foveolar cells: 194.5;Goblet cells: 216.6" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 70.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078008 Approved "Centriolar satellite" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 12 "Centriolar satellite" "HPA078008: " "unprognostic (2.83e-1)" "unprognostic (1.69e-1)" "unprognostic (8.57e-2)" "unprognostic (2.18e-1)" "unprognostic (2.79e-1)" "unprognostic (8.84e-2)" "unprognostic (4.28e-3)" "unprognostic (6.81e-2)" "unprognostic (1.91e-2)" "unprognostic (2.28e-1)" "unprognostic (1.52e-3)" "unprognostic (9.63e-3)" "unprognostic (1.45e-1)" "unprognostic (1.69e-1)" "unprognostic (1.42e-1)" "unprognostic (1.48e-3)" "unprognostic (5.70e-3)" "unprognostic (4.43e-2)" "unprognostic (8.23e-3)" "unprognostic (4.25e-2)" "unprognostic (2.47e-2)" "unprognostic (1.12e-3)" "unprognostic (5.73e-2)" "unprognostic (1.08e-1)" "unprognostic (1.82e-1)" "unprognostic (6.76e-2)" "unprognostic (3.11e-1)" "unprognostic (1.21e-1)" "unprognostic (1.33e-2)" "unprognostic (3.28e-1)" "unprognostic (1.34e-1)" POLDIP2 "DKFZP586F1524, PDIP38" ENSG00000004142 "DNA polymerase delta interacting protein 2" Q9Y2S7 17 28346633-28357527 "Essential proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 255.8" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 168.4;Esophageal suprabasal cells: 167.4;Hepatocytes: 157.0;Late spermatids: 248.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007700 Approved Mitochondria NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 32 Mitochondria "HPA007700: " "unprognostic (1.85e-1)" "unprognostic (3.39e-3)" "unprognostic (2.03e-1)" "potential prognostic unfavorable (3.56e-4)" "unprognostic (2.92e-2)" "unprognostic (4.65e-2)" "unprognostic (3.02e-1)" "unprognostic (8.61e-3)" "unprognostic (8.08e-3)" "unprognostic (6.15e-3)" "unprognostic (8.33e-2)" "unprognostic (5.41e-2)" "unprognostic (3.57e-3)" "unprognostic (1.11e-1)" "potential prognostic unfavorable (1.74e-4)" "unprognostic (1.11e-2)" "unprognostic (1.13e-2)" "unprognostic (2.57e-2)" "unprognostic (7.38e-2)" "unprognostic (4.11e-2)" "unprognostic (4.23e-1)" "unprognostic (8.93e-2)" "unprognostic (1.21e-2)" "unprognostic (1.12e-1)" "unprognostic (1.73e-3)" "unprognostic (1.25e-2)" "unprognostic (3.74e-2)" "unprognostic (1.96e-1)" "unprognostic (2.43e-1)" "unprognostic (2.75e-2)" "unprognostic (2.60e-1)" POLDIP3 "KIAA1649, PDIP3, PDIP46, SKAR" ENSG00000100227 "DNA polymerase delta interacting protein 3" Q9BY77 22 42583721-42614962 "Predicted intracellular proteins" "mRNA transport, Translation regulation, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018419, HPA048790" Approved Enhanced "Nuclear speckles,Cytoplasmic bodies" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 54: Non-specific - Ribosome" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 102: Non-specific - Mixed function" 27 "Nuclear speckles" "Cytoplasmic bodies" "HPA018419: , HPA048790: " "unprognostic (3.07e-1)" "unprognostic (1.16e-1)" "unprognostic (3.07e-1)" "unprognostic (4.26e-2)" "unprognostic (2.30e-1)" "unprognostic (6.57e-3)" "unprognostic (2.35e-3)" "potential prognostic favorable (7.71e-4)" "unprognostic (1.46e-1)" "unprognostic (1.14e-1)" "validated prognostic favorable (5.39e-5)" "validated prognostic favorable (1.32e-4)" "unprognostic (1.30e-1)" "unprognostic (5.95e-3)" "unprognostic (3.97e-2)" "unprognostic (3.71e-2)" "unprognostic (4.20e-2)" "unprognostic (1.43e-1)" "potential prognostic favorable (6.14e-4)" "unprognostic (9.68e-3)" "unprognostic (2.24e-1)" "unprognostic (1.71e-1)" "unprognostic (7.83e-2)" "unprognostic (2.79e-1)" "unprognostic (7.19e-2)" "unprognostic (7.26e-2)" "unprognostic (5.73e-2)" "unprognostic (9.71e-2)" "unprognostic (7.84e-2)" "unprognostic (7.96e-2)" "unprognostic (1.38e-1)" POLE POLE1 ENSG00000177084 "DNA polymerase epsilon, catalytic subunit" Q07864 12 132623753-132687376 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication" "DNA-binding, DNA-directed DNA polymerase, Hydrolase, Nucleotidyltransferase, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.8" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 97.0;Erythrocyte progenitors: 74.0;Megakaryocyte progenitors: 60.6;Megakaryocyte-Erythroid progenitors: 57.5;Neutrophil progenitors: 125.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA058210, HPA067385" Enhanced "Nucleoplasm,Plasma membrane" NA NA "Cluster 44: Bone marrow - Nuclear processes" "Cluster 15: Non-specific - Transcription" "Cluster 54: Non-specific - Transcription" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 43 Nucleoplasm "Plasma membrane" "HPA058210: , HPA067385: " "unprognostic (2.75e-2)" "unprognostic (9.47e-2)" "unprognostic (1.33e-1)" "unprognostic (1.97e-3)" "unprognostic (1.19e-1)" "unprognostic (1.25e-1)" "unprognostic (4.30e-1)" "unprognostic (5.05e-2)" "unprognostic (2.09e-2)" "unprognostic (6.35e-3)" "unprognostic (9.94e-3)" "unprognostic (1.69e-1)" "unprognostic (1.98e-2)" "unprognostic (6.50e-2)" "unprognostic (8.61e-2)" "unprognostic (1.24e-1)" "unprognostic (1.41e-3)" "unprognostic (1.46e-1)" "unprognostic (3.07e-3)" "unprognostic (2.71e-1)" "unprognostic (1.73e-3)" "unprognostic (4.77e-2)" "unprognostic (5.60e-3)" "unprognostic (1.70e-1)" "unprognostic (1.67e-3)" "unprognostic (7.50e-3)" "potential prognostic unfavorable (6.82e-4)" "unprognostic (4.00e-1)" "unprognostic (3.03e-1)" "unprognostic (1.39e-2)" "unprognostic (4.00e-3)" POLE2 DPE2 ENSG00000100479 "DNA polymerase epsilon 2, accessory subunit" P56282 14 49643555-49688422 "Essential proteins, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "DNA replication" DNA-binding "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.3" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 81.7;Erythrocyte progenitors: 180.9;Megakaryocyte progenitors: 134.5;Megakaryocyte-Erythroid progenitors: 84.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 1.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA027555 Uncertain Supported "Nucleoplasm,Nuclear bodies,Vesicles" No No "Cluster 16: Non-specific - Cell proliferation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 9: Non-specific - Receptor signaling" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 24 "Nucleoplasm, Nuclear bodies" Vesicles "HPA027555: " "unprognostic (6.46e-2)" "unprognostic (3.63e-1)" "unprognostic (8.20e-3)" "unprognostic (7.30e-3)" "unprognostic (4.33e-2)" "unprognostic (7.58e-2)" "unprognostic (7.81e-2)" "unprognostic (1.42e-1)" "unprognostic (2.10e-3)" "potential prognostic unfavorable (5.04e-4)" "unprognostic (3.80e-2)" "unprognostic (6.68e-2)" "unprognostic (1.14e-1)" "validated prognostic unfavorable (2.63e-4)" "validated prognostic unfavorable (1.70e-4)" "potential prognostic unfavorable (7.54e-5)" "unprognostic (6.87e-3)" "unprognostic (1.31e-2)" "unprognostic (4.28e-1)" "unprognostic (1.04e-1)" "unprognostic (1.79e-3)" "validated prognostic unfavorable (4.67e-4)" "validated prognostic unfavorable (2.21e-4)" "unprognostic (4.53e-3)" "unprognostic (1.45e-3)" "unprognostic (2.80e-1)" "unprognostic (4.31e-3)" "unprognostic (1.64e-1)" "unprognostic (1.02e-1)" "unprognostic (2.62e-1)" "unprognostic (3.46e-2)" POLE3 "CHARAC17, CHRAC17, CHRAC2, p17, Ybl1" ENSG00000148229 "DNA polymerase epsilon 3, accessory subunit" Q9NRF9 9 113407235-113410675 "FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" DNA-binding "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 225.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004477, HPA047945" Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 37: Neurons - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 35 Nucleoplasm "Nucleoli, Cytosol" "HPA004477: , HPA047945: " "unprognostic (1.66e-1)" "unprognostic (1.60e-2)" "unprognostic (5.29e-2)" "unprognostic (4.67e-2)" "unprognostic (8.96e-2)" "unprognostic (1.92e-2)" "unprognostic (6.25e-3)" "unprognostic (1.59e-3)" "unprognostic (2.28e-2)" "unprognostic (2.34e-2)" "potential prognostic favorable (3.59e-7)" "unprognostic (3.35e-2)" "unprognostic (9.42e-2)" "validated prognostic unfavorable (9.31e-5)" "validated prognostic unfavorable (2.81e-4)" "unprognostic (7.02e-3)" "unprognostic (1.87e-3)" "unprognostic (1.23e-1)" "unprognostic (7.82e-2)" "unprognostic (3.32e-1)" "unprognostic (3.47e-1)" "unprognostic (9.74e-3)" "unprognostic (2.02e-1)" "unprognostic (1.42e-3)" "unprognostic (1.70e-1)" "unprognostic (2.32e-1)" "unprognostic (1.34e-1)" "unprognostic (1.02e-1)" "unprognostic (1.67e-1)" "unprognostic (4.19e-1)" "unprognostic (5.44e-3)" POLE4 p12 ENSG00000115350 "DNA polymerase epsilon 4, accessory subunit" Q9NR33 2 74958643-74970128 "FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" DNA-binding "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 368.4;Parietal cells: 323.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054979, HPA071815, HPA076606" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 33: Neurons - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 20 Nucleoplasm Cytosol "HPA054979: , HPA071815: , HPA076606: " "unprognostic (1.46e-3)" "unprognostic (6.77e-2)" "unprognostic (1.65e-1)" "unprognostic (9.30e-2)" "unprognostic (2.04e-1)" "unprognostic (3.01e-1)" "unprognostic (5.23e-2)" "unprognostic (6.59e-2)" "unprognostic (4.29e-2)" "unprognostic (1.25e-2)" "unprognostic (1.25e-1)" "unprognostic (2.16e-1)" "unprognostic (1.05e-2)" "validated prognostic unfavorable (8.82e-4)" "validated prognostic unfavorable (1.66e-6)" "potential prognostic unfavorable (4.37e-4)" "unprognostic (6.32e-2)" "unprognostic (1.84e-1)" "unprognostic (1.29e-1)" "unprognostic (1.44e-1)" "unprognostic (8.33e-2)" "unprognostic (2.32e-1)" "unprognostic (5.04e-2)" "unprognostic (6.37e-2)" "unprognostic (2.29e-1)" "unprognostic (1.46e-1)" "unprognostic (1.61e-3)" "unprognostic (2.43e-3)" "unprognostic (2.98e-1)" "unprognostic (1.73e-1)" "unprognostic (6.28e-2)" POLG "POLG1, POLGA" ENSG00000140521 "DNA polymerase gamma, catalytic subunit" P54098 15 89305198-89334861 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA replication" "DNA-binding, DNA-directed DNA polymerase, Hydrolase, Lyase, Nucleotidyltransferase, Transferase" "Disease variant, Epilepsy, Leigh syndrome, Neurodegeneration, Neuropathy, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056821, HPA078482" Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 24: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 28 Mitochondria "HPA056821: , HPA078482: " "unprognostic (1.28e-2)" "unprognostic (1.63e-1)" "unprognostic (1.14e-1)" "unprognostic (2.98e-2)" "unprognostic (2.54e-1)" "unprognostic (1.13e-1)" "unprognostic (4.20e-1)" "potential prognostic favorable (3.07e-5)" "unprognostic (5.28e-1)" "unprognostic (7.65e-2)" "potential prognostic favorable (2.81e-5)" "unprognostic (8.11e-2)" "unprognostic (1.76e-1)" "unprognostic (4.14e-2)" "unprognostic (1.47e-2)" "unprognostic (9.63e-3)" "unprognostic (3.02e-1)" "unprognostic (3.77e-2)" "unprognostic (2.97e-1)" "unprognostic (3.45e-1)" "potential prognostic favorable (8.57e-4)" "unprognostic (5.97e-3)" "unprognostic (9.11e-2)" "unprognostic (3.56e-3)" "unprognostic (2.50e-1)" "unprognostic (2.44e-1)" "unprognostic (2.11e-1)" "unprognostic (2.52e-2)" "unprognostic (2.76e-1)" "unprognostic (3.09e-2)" "unprognostic (2.09e-1)" POLG2 "HP55, MTPOLB" ENSG00000256525 "DNA polymerase gamma 2, accessory subunit" Q9UHN1 17 64477785-64497054 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "DNA replication" DNA-binding "Disease variant, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017030, HPA023202, HPA078396" Approved Supported "Nuclear bodies,Mitochondria" NA NA "Cluster 18: Non-specific - Translation" "Cluster 39: Testis - Nuclear processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 27: Breast cancer - Unknown function" "Cluster 20: Non-specific - Transcription regulation" 14 Mitochondria "Nuclear bodies" "CAB017030: , HPA023202: , HPA078396: " "unprognostic (2.09e-1)" "unprognostic (2.03e-1)" "unprognostic (7.43e-2)" "unprognostic (4.30e-2)" "unprognostic (2.67e-1)" "unprognostic (2.93e-1)" "unprognostic (2.28e-2)" "unprognostic (4.49e-2)" "unprognostic (2.51e-2)" "unprognostic (9.54e-2)" "unprognostic (7.06e-3)" "unprognostic (2.71e-2)" "unprognostic (2.26e-1)" "validated prognostic unfavorable (8.18e-5)" "validated prognostic unfavorable (1.52e-4)" "unprognostic (1.39e-2)" "unprognostic (1.82e-3)" "unprognostic (7.65e-2)" "unprognostic (3.92e-2)" "unprognostic (7.97e-2)" "unprognostic (3.47e-1)" "unprognostic (5.34e-2)" "potential prognostic unfavorable (1.14e-5)" "potential prognostic unfavorable (2.13e-4)" "unprognostic (2.76e-3)" "unprognostic (3.29e-2)" "unprognostic (6.94e-2)" "unprognostic (9.05e-2)" "unprognostic (1.04e-1)" "unprognostic (8.12e-2)" "unprognostic (8.07e-2)" POLGARF ORF-Y ENSG00000291307 "POLG alternative reading frame" A0A3B3IS91 15 89330208-89333809 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "neutrophil: 3.1" "Lineage enriched" "Detected in single" 20 "granulocytes: 3.1" "Not detected" "Not detected" "Secreted - unknown location" "No annotated function" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 18: Non-specific - Mixed function" "Cluster 67: Non-specific - Unknown function" POLH "RAD30A, XP-V" ENSG00000170734 "DNA polymerase eta" Q9Y253 6 43576185-43620523 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, DNA synthesis" "DNA-binding, DNA-directed DNA polymerase, Mutator protein, Nucleotidyltransferase, Transferase" "Disease variant, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006721, HPA026762" Approved Enhanced Nucleoplasm NA Yes "Cluster 3: Non-specific - Nuclear processes" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 6: Non-specific - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 65: Non-specific - Cell growth & division" 31 Nucleoplasm "HPA006721: , HPA026762: " "unprognostic (3.89e-3)" "unprognostic (4.21e-2)" "unprognostic (1.66e-1)" "unprognostic (7.76e-3)" "unprognostic (6.20e-2)" "unprognostic (1.68e-1)" "unprognostic (1.58e-1)" "unprognostic (4.10e-2)" "unprognostic (2.11e-2)" "unprognostic (1.01e-1)" "validated prognostic favorable (1.86e-4)" "validated prognostic favorable (2.00e-5)" "unprognostic (4.10e-3)" "unprognostic (1.64e-1)" "unprognostic (1.46e-1)" "unprognostic (1.08e-1)" "unprognostic (1.06e-1)" "unprognostic (3.26e-2)" "unprognostic (1.84e-1)" "unprognostic (1.21e-1)" "unprognostic (1.01e-1)" "unprognostic (3.97e-3)" "unprognostic (2.13e-1)" "unprognostic (1.04e-1)" "unprognostic (3.34e-2)" "unprognostic (2.77e-1)" "unprognostic (2.44e-1)" "unprognostic (3.10e-2)" "unprognostic (3.83e-2)" "unprognostic (3.16e-2)" "unprognostic (1.71e-1)" POLI "RAD30B, RAD3OB" ENSG00000101751 "DNA polymerase iota" Q9UNA4 18 54269517-54321266 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, DNA synthesis" "DNA-binding, DNA-directed DNA polymerase, Mutator protein, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 93.3;Late primary spermatocytes: 148.5;Sertoli cells: 92.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012000, HPA064696" Enhanced Supported "Nuclear speckles,Cytoplasmic bodies" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 42: Retina - Visual perception" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 89: Adipocytes - Lipid metabolism" 22 "Nuclear speckles" "Cytoplasmic bodies" "HPA012000: , HPA064696: " "unprognostic (5.11e-2)" "unprognostic (3.69e-1)" "unprognostic (2.05e-1)" "unprognostic (2.66e-2)" "unprognostic (2.81e-1)" "unprognostic (1.35e-1)" "unprognostic (6.54e-2)" "unprognostic (1.30e-1)" "unprognostic (2.73e-1)" "unprognostic (6.81e-3)" "validated prognostic favorable (1.09e-6)" "validated prognostic favorable (4.84e-4)" "unprognostic (2.92e-3)" "unprognostic (2.89e-2)" "unprognostic (5.95e-2)" "unprognostic (5.15e-2)" "unprognostic (2.35e-2)" "unprognostic (2.14e-1)" "unprognostic (7.69e-2)" "unprognostic (1.31e-1)" "unprognostic (2.94e-1)" "unprognostic (3.51e-1)" "unprognostic (5.15e-2)" "unprognostic (6.37e-3)" "unprognostic (4.76e-3)" "unprognostic (9.22e-2)" "unprognostic (1.89e-1)" "unprognostic (6.73e-2)" "unprognostic (1.08e-1)" "unprognostic (4.87e-3)" "unprognostic (6.50e-2)" POLK "DINB1, DINP, POLQ" ENSG00000122008 "DNA polymerase kappa" Q9UBT6 5 75511845-75609991 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, DNA synthesis" "DNA-binding, DNA-directed DNA polymerase, Mutator protein, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012035, HPA057303, HPA068117, HPA069375" Enhanced Nucleoplasm NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 7: Non-specific - Transcription" 8 Nucleoplasm "HPA012035: , HPA057303: , HPA068117: , HPA069375: " "unprognostic (1.14e-2)" "unprognostic (2.78e-1)" "unprognostic (3.13e-1)" "unprognostic (2.90e-2)" "unprognostic (3.81e-2)" "unprognostic (1.23e-1)" "unprognostic (4.34e-1)" "unprognostic (2.04e-1)" "unprognostic (5.11e-2)" "unprognostic (7.55e-3)" "unprognostic (1.59e-3)" "unprognostic (3.46e-2)" "unprognostic (1.03e-1)" "potential prognostic unfavorable (1.05e-4)" "unprognostic (7.68e-2)" "unprognostic (1.42e-2)" "unprognostic (1.33e-1)" "unprognostic (2.23e-1)" "unprognostic (3.81e-1)" "unprognostic (1.59e-1)" "unprognostic (1.48e-3)" "unprognostic (1.77e-1)" "potential prognostic unfavorable (4.08e-4)" "unprognostic (5.61e-2)" "unprognostic (7.27e-2)" "unprognostic (1.24e-1)" "unprognostic (1.39e-1)" "unprognostic (6.76e-3)" "unprognostic (2.28e-1)" "unprognostic (7.27e-2)" "unprognostic (1.96e-1)" POLL ENSG00000166169 "DNA polymerase lambda" Q9UGP5 10 101578882-101588270 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, DNA synthesis" "DNA-binding, DNA-directed DNA polymerase, Lyase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 71.0;Late spermatids: 84.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076828 Supported Nucleoplasm NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 21: Testis - Mixed function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 7: Non-specific - Transcription" 14 Nucleoplasm "HPA076828: " "unprognostic (5.43e-2)" "unprognostic (5.73e-2)" "unprognostic (3.84e-2)" "unprognostic (2.64e-2)" "unprognostic (2.86e-2)" "unprognostic (4.72e-2)" "unprognostic (1.34e-1)" "potential prognostic favorable (2.15e-4)" "unprognostic (3.17e-2)" "unprognostic (4.60e-2)" "potential prognostic favorable (1.37e-4)" "unprognostic (1.14e-3)" "unprognostic (6.58e-3)" "unprognostic (5.30e-3)" "unprognostic (1.73e-1)" "unprognostic (1.46e-1)" "unprognostic (2.71e-1)" "unprognostic (2.13e-1)" "unprognostic (2.97e-2)" "unprognostic (4.89e-3)" "unprognostic (5.54e-2)" "unprognostic (2.09e-2)" "unprognostic (1.00e-2)" "unprognostic (2.94e-1)" "unprognostic (2.27e-3)" "unprognostic (4.04e-2)" "unprognostic (2.76e-2)" "unprognostic (1.38e-1)" "unprognostic (1.63e-1)" "unprognostic (2.98e-2)" "unprognostic (9.87e-2)" POLM Tdt-N ENSG00000122678 "DNA polymerase mu" Q9NP87 7 44072062-44082530 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" "DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 63.8" "Lineage enriched" "Detected in all" 6 "granulocytes: 63.8" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058900, HPA078005" Supported Nucleoplasm NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 49: Non-specific - Transcription" "Cluster 19: Astrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" Nucleoplasm "HPA058900: , HPA078005: " "unprognostic (2.21e-2)" "unprognostic (8.74e-2)" "unprognostic (1.18e-1)" "unprognostic (1.62e-3)" "unprognostic (7.99e-3)" "unprognostic (1.18e-1)" "unprognostic (7.50e-2)" "unprognostic (2.31e-1)" "unprognostic (1.61e-1)" "unprognostic (3.51e-2)" "unprognostic (1.17e-2)" "unprognostic (1.45e-1)" "unprognostic (5.99e-2)" "unprognostic (5.84e-2)" "unprognostic (1.63e-1)" "potential prognostic unfavorable (3.08e-4)" "unprognostic (2.97e-1)" "unprognostic (2.78e-1)" "unprognostic (4.99e-2)" "unprognostic (9.91e-2)" "unprognostic (9.39e-2)" "unprognostic (1.80e-1)" "potential prognostic unfavorable (6.63e-4)" "unprognostic (8.40e-2)" "unprognostic (3.14e-1)" "unprognostic (5.60e-2)" "unprognostic (2.91e-1)" "unprognostic (4.90e-2)" "unprognostic (1.28e-1)" "unprognostic (2.29e-1)" "unprognostic (2.96e-1)" POLN ENSG00000130997 "DNA polymerase nu" Q7Z5Q5 4 2071918-2242121 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication" "DNA-binding, DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 2.2;testis: 1.8" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 15.9;Early primary spermatocytes: 11.1;Late spermatids: 19.6;Loop of henle epithelial cells: 25.0;Papillary tip epithelial cells: 16.4;Podocytes: 17.8;Proximal tubule cells: 19.9;Renal collecting duct intercalated cells: 11.9;Renal collecting duct principal cells: 22.2;Renal connecting tubule cells: 14.9" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in single" "Prostate Adenocarcinoma (TCGA): 1.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Adipocytes (Visceral), Prostate - Prostate glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA035939, HPA035940" Enhanced Nucleoplasm NA NA "Cluster 67: Testis - Mixed function" "Cluster 34: Non-specific - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 105: Non-specific - Mixed function" 6 Nucleoplasm "HPA035939: , HPA035940: " "unprognostic (2.86e-1)" "unprognostic (8.66e-3)" "unprognostic (2.26e-1)" "unprognostic (1.54e-1)" "unprognostic (7.29e-3)" "unprognostic (9.82e-2)" POLQ POLH ENSG00000051341 "DNA polymerase theta" O75417 3 121431431-121545988 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-directed DNA polymerase, Helicase, Hydrolase, Multifunctional enzyme, Nucleotidyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.6;lymphoid tissue: 4.2" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 176.9;Megakaryocyte progenitors: 110.8;Monocyte progenitors: 216.6;Neutrophil progenitors: 109.8;Plasma cells: 45.3;Sertoli cells: 91.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Thyroid gland - Mitotic cells (Thyroid)" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 3.5" HPA053359 Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA Yes "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 37: Neurons - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 27: Non-specific - Cell proliferation" 4 Nucleoplasm "Golgi apparatus, Cytosol" "HPA053359: " "unprognostic (5.61e-2)" "unprognostic (2.96e-1)" "unprognostic (8.87e-2)" "unprognostic (1.26e-1)" "unprognostic (1.46e-1)" "unprognostic (7.66e-2)" "unprognostic (7.09e-2)" "unprognostic (1.91e-2)" "potential prognostic unfavorable (4.16e-5)" "potential prognostic unfavorable (2.58e-4)" "unprognostic (3.42e-3)" "unprognostic (2.90e-2)" "unprognostic (6.75e-2)" "unprognostic (3.20e-1)" "unprognostic (1.62e-1)" "potential prognostic unfavorable (3.86e-4)" "unprognostic (4.18e-2)" "unprognostic (1.96e-2)" "unprognostic (1.79e-3)" "unprognostic (1.24e-3)" "unprognostic (2.21e-1)" "unprognostic (1.14e-2)" POLR1A "DKFZP586M0122, FLJ21915, RPA1, RPA190, RPO1-4" ENSG00000068654 "RNA polymerase I subunit A" O95602 2 86020216-86106155 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Nucleotidyltransferase, Transferase" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010145, HPA031513, HPA031514, HPA049700" Supported Enhanced "Nucleoplasm,Nucleoli fibrillar center,Cytosol" No No "Cluster 30: Non-specific - DNA binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 17: Non-specific - RNA processing" 77 "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "CAB010145: , HPA031513: , HPA031514: , HPA049700: " "unprognostic (3.11e-1)" "unprognostic (6.29e-2)" "unprognostic (4.01e-3)" "unprognostic (2.65e-3)" "unprognostic (2.44e-2)" "unprognostic (4.59e-1)" "unprognostic (1.79e-1)" "unprognostic (3.23e-1)" "unprognostic (1.53e-1)" "unprognostic (1.53e-3)" "unprognostic (3.38e-3)" "unprognostic (1.78e-1)" "unprognostic (2.86e-1)" "potential prognostic unfavorable (1.35e-5)" "unprognostic (2.95e-3)" "unprognostic (2.65e-3)" "potential prognostic unfavorable (7.50e-6)" "unprognostic (2.39e-1)" "unprognostic (1.55e-3)" "unprognostic (4.66e-3)" "unprognostic (7.12e-2)" "unprognostic (1.79e-3)" "unprognostic (4.45e-1)" "unprognostic (6.92e-2)" "unprognostic (1.39e-2)" "unprognostic (2.18e-2)" "unprognostic (3.25e-3)" "unprognostic (7.94e-2)" "unprognostic (2.42e-1)" "unprognostic (9.39e-3)" "unprognostic (7.23e-2)" POLR1B "FLJ10816, FLJ21921, RPA135, RPA2, Rpo1-2" ENSG00000125630 "RNA polymerase I subunit B" Q9H9Y6 2 112541915-112579818 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Nucleotidyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 192.6;Late primary spermatocytes: 131.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037528 Supported "Nucleoli fibrillar center,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 49 "Nucleoli fibrillar center" Cytosol "HPA037528: " "unprognostic (3.11e-2)" "unprognostic (4.09e-1)" "unprognostic (2.14e-1)" "unprognostic (6.81e-3)" "unprognostic (2.20e-1)" "unprognostic (3.03e-1)" "unprognostic (1.11e-1)" "unprognostic (1.89e-2)" "unprognostic (4.84e-2)" "unprognostic (2.41e-3)" "potential prognostic favorable (1.54e-7)" "unprognostic (1.94e-3)" "potential prognostic unfavorable (5.37e-5)" "unprognostic (1.01e-2)" "unprognostic (9.90e-2)" "unprognostic (9.37e-2)" "unprognostic (3.64e-3)" "unprognostic (1.25e-1)" "unprognostic (1.86e-2)" "unprognostic (1.07e-1)" "unprognostic (7.94e-2)" "unprognostic (2.45e-3)" "unprognostic (2.50e-1)" "unprognostic (1.56e-2)" "unprognostic (4.91e-2)" "unprognostic (5.75e-2)" "unprognostic (4.85e-1)" "unprognostic (1.85e-1)" "unprognostic (4.91e-1)" "unprognostic (8.24e-2)" "unprognostic (7.62e-2)" POLR1C "AC40, RPA39, RPA40, RPA5, RPAC1, RPC40" ENSG00000171453 "RNA polymerase I and III subunit C" O15160 6 43509702-43562419 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 205.6;Epicardial cells: 236.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031010 Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 215 "Nucleoplasm, Nucleoli fibrillar center" "HPA031010: " "unprognostic (5.75e-1)" "unprognostic (6.32e-3)" "unprognostic (5.86e-2)" "unprognostic (1.95e-1)" "unprognostic (1.95e-1)" "unprognostic (2.27e-1)" "unprognostic (1.63e-1)" "unprognostic (9.14e-3)" "unprognostic (1.63e-1)" "potential prognostic unfavorable (7.94e-4)" "unprognostic (3.42e-3)" "unprognostic (5.03e-2)" "unprognostic (1.26e-2)" "unprognostic (3.57e-3)" "unprognostic (1.02e-3)" "unprognostic (2.49e-2)" "unprognostic (1.14e-2)" "unprognostic (3.46e-2)" "unprognostic (1.93e-2)" "unprognostic (1.03e-1)" "unprognostic (1.19e-1)" "unprognostic (1.59e-1)" "unprognostic (1.38e-1)" "unprognostic (4.33e-2)" "unprognostic (3.65e-3)" "unprognostic (6.52e-3)" "unprognostic (3.69e-3)" "unprognostic (7.23e-2)" "unprognostic (4.82e-2)" "unprognostic (2.74e-2)" "unprognostic (1.26e-2)" POLR1D "AC19, MGC9850, RPA16, RPA9, RPAC2, RPO1-3" ENSG00000186184 "RNA polymerase I and III subunit D" "P0DPB5, P0DPB6" 13 27620742-27744237 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1418.9;Late primary spermatocytes: 571.9;Late spermatids: 1306.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039337 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 54: Non-specific - Ribosome" "Cluster 35: Non-specific - DNA binding" "Cluster 19: Non-specific - Unknown function" "Cluster 84: Apical squamous epithelium - Cornification" 133 "Nucleoplasm, Golgi apparatus" "HPA039337: " "unprognostic (2.43e-1)" "potential prognostic favorable (8.01e-4)" "unprognostic (1.47e-1)" "unprognostic (1.74e-2)" "unprognostic (8.95e-2)" "unprognostic (1.78e-1)" "unprognostic (4.92e-3)" "potential prognostic unfavorable (1.93e-5)" "potential prognostic unfavorable (1.54e-4)" "unprognostic (5.07e-2)" "potential prognostic favorable (9.33e-8)" "unprognostic (2.72e-3)" "unprognostic (3.74e-2)" "validated prognostic unfavorable (5.00e-4)" "validated prognostic unfavorable (5.30e-5)" "unprognostic (3.34e-1)" "unprognostic (8.23e-3)" "unprognostic (2.72e-2)" "unprognostic (2.90e-1)" "unprognostic (9.16e-3)" "unprognostic (5.64e-2)" "unprognostic (1.06e-1)" "unprognostic (1.87e-2)" "unprognostic (4.99e-2)" "unprognostic (3.01e-1)" "unprognostic (1.54e-1)" "unprognostic (2.99e-1)" "unprognostic (2.15e-1)" "unprognostic (1.03e-2)" "unprognostic (2.15e-1)" "unprognostic (1.55e-2)" POLR1E "FLJ13390, FLJ13970, PAF53, PRAF1, RPA49" ENSG00000137054 "RNA polymerase I subunit E" Q9GZS1 9 37485948-37503697 "Essential proteins, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, RNA polymerase related proteins" Transcription "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 53.5;Plasma cells: 49.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022527, HPA052400" Supported Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 54: Non-specific - Ribosome" "Cluster 55: Non-specific - Transcription" "Cluster 25: Non-specific - Ribosome" "Cluster 44: Plasma cells - Antibody production & secretion" 69 "Nucleoplasm, Nucleoli fibrillar center" "HPA022527: , HPA052400: " "unprognostic (3.64e-2)" "potential prognostic favorable (7.16e-4)" "unprognostic (2.06e-1)" "unprognostic (2.69e-1)" "unprognostic (3.10e-1)" "unprognostic (8.00e-2)" "unprognostic (4.34e-2)" "unprognostic (9.64e-3)" "unprognostic (2.59e-1)" "unprognostic (1.30e-1)" "validated prognostic favorable (2.51e-8)" "validated prognostic favorable (6.09e-5)" "unprognostic (2.89e-3)" "potential prognostic unfavorable (5.86e-4)" "unprognostic (1.13e-2)" "unprognostic (2.75e-1)" "potential prognostic unfavorable (2.31e-4)" "unprognostic (1.96e-1)" "unprognostic (9.21e-2)" "unprognostic (1.05e-1)" "unprognostic (1.57e-1)" "unprognostic (7.61e-2)" "unprognostic (2.41e-1)" "unprognostic (1.53e-1)" "unprognostic (2.56e-1)" "unprognostic (1.06e-1)" "unprognostic (9.08e-2)" "unprognostic (9.14e-2)" "unprognostic (1.69e-1)" "unprognostic (1.21e-1)" "unprognostic (3.57e-1)" POLR1F "A43, RPA43, TWISTNB" ENSG00000105849 "RNA polymerase I subunit F" Q3B726 7 19695461-19709037 "Essential proteins, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 211.2;Endometrial luminal cells: 182.0;Endometrial stromal cells: 191.2;monocytes: 156.8;Oocytes: 142.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019071, HPA022416" Approved Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 20 "Nucleoli fibrillar center" Nucleoplasm "HPA019071: , HPA022416: " "unprognostic (1.14e-1)" "unprognostic (2.29e-2)" "unprognostic (6.38e-3)" "unprognostic (1.27e-1)" "unprognostic (2.17e-1)" "unprognostic (9.61e-2)" "unprognostic (4.51e-3)" "unprognostic (4.05e-2)" "unprognostic (1.45e-3)" "validated prognostic favorable (1.27e-5)" "validated prognostic favorable (1.23e-4)" "unprognostic (1.73e-1)" "potential prognostic unfavorable (3.50e-4)" "unprognostic (3.82e-3)" "potential prognostic unfavorable (8.28e-4)" "unprognostic (1.36e-1)" "unprognostic (1.87e-1)" "unprognostic (9.68e-2)" "unprognostic (5.03e-3)" "unprognostic (5.23e-2)" "unprognostic (4.70e-2)" "unprognostic (4.39e-2)" "unprognostic (4.73e-2)" "unprognostic (1.75e-1)" "unprognostic (1.39e-1)" "unprognostic (1.08e-1)" "unprognostic (3.33e-1)" "unprognostic (3.09e-2)" "unprognostic (2.32e-1)" POLR1G "A34.5, ASE-1, CAST, CD3EAP, PAF49, RPA34" ENSG00000117877 "RNA polymerase I subunit G" O15446 19 45406644-45410737 "Essential proteins, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 107.9;Cardiomyocytes: 46.5;Esophageal basal cells: 47.5;Gastric progenitor cells: 62.8;Suprabasal keratinocytes: 83.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 14.5" "Lineage enriched" "Detected in all" 4 "dendritic cells: 14.5" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041664, HPA041734" Supported Enhanced "Nucleoplasm,Nucleoli fibrillar center,Mitochondria" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 9: Non-specific - Receptor signaling" "Cluster 4: Non-specific - Transcription" "Cluster 26: Keratinocytes - Keratinization" 40 "Nucleoplasm, Nucleoli fibrillar center" Mitochondria "HPA041664: , HPA041734: " "unprognostic (5.44e-2)" "unprognostic (1.59e-2)" "unprognostic (3.96e-3)" "unprognostic (3.11e-1)" "unprognostic (1.55e-1)" "unprognostic (1.77e-1)" "unprognostic (3.17e-1)" "potential prognostic unfavorable (7.34e-4)" "unprognostic (1.98e-2)" "unprognostic (5.52e-2)" "unprognostic (3.68e-1)" "unprognostic (6.87e-2)" "potential prognostic unfavorable (5.64e-7)" "unprognostic (1.59e-3)" "potential prognostic unfavorable (2.80e-4)" "unprognostic (2.12e-1)" "unprognostic (2.01e-1)" "unprognostic (2.14e-1)" "unprognostic (9.84e-3)" "potential prognostic unfavorable (5.25e-4)" "unprognostic (2.99e-1)" "unprognostic (5.89e-3)" "unprognostic (3.63e-2)" "unprognostic (2.82e-2)" "unprognostic (2.51e-2)" "unprognostic (5.93e-2)" "unprognostic (5.01e-1)" "unprognostic (1.79e-1)" "unprognostic (1.29e-1)" POLR1H "A12.2, HTEX-6, hZR14, RPA12, tctex-6, ZNRD1" ENSG00000066379 "RNA polymerase I subunit H" Q9P1U0 6 30058899-30064909 "Essential proteins, Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 112.5;Late primary spermatocytes: 207.5;Megakaryocytes: 92.7" "Cell type enhanced" "Detected in all" "vascular associated smooth muscle cell: 37.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055074, HPA077979" Supported Supported "Nucleoli fibrillar center" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 28: Non-specific - Nuclear processes" "Cluster 103: Non-specific - Basic cellular processes" 13 "Nucleoli fibrillar center" "HPA055074: , HPA077979: " "unprognostic (2.64e-2)" "unprognostic (1.83e-1)" "unprognostic (1.67e-1)" "unprognostic (2.69e-1)" "unprognostic (2.47e-2)" "unprognostic (1.96e-2)" "unprognostic (1.04e-3)" "unprognostic (4.14e-2)" "unprognostic (1.74e-2)" "unprognostic (3.83e-2)" "unprognostic (1.29e-1)" "unprognostic (3.47e-3)" "unprognostic (2.44e-3)" "unprognostic (2.36e-2)" "unprognostic (1.72e-2)" "unprognostic (2.24e-2)" "unprognostic (7.41e-2)" "unprognostic (4.62e-2)" "unprognostic (2.88e-1)" "unprognostic (4.29e-3)" "unprognostic (1.47e-1)" "unprognostic (2.17e-1)" "unprognostic (7.58e-3)" "unprognostic (1.04e-2)" "unprognostic (1.83e-2)" "unprognostic (4.62e-2)" "unprognostic (1.00e-1)" "unprognostic (7.95e-2)" "unprognostic (1.06e-1)" POLR2A "POLR2, POLRA, RPB1" ENSG00000181222 "RNA polymerase II subunit A" 17 7484366-7514616 "Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.5" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 74.5;Distal convoluted tubule cells: 56.5;Loop of henle epithelial cells: 71.4;Papillary tip epithelial cells: 62.0;Podocytes: 65.6;Proximal tubule cells: 48.6;Renal collecting duct intercalated cells: 91.5;Renal collecting duct principal cells: 80.2;Renal connecting tubule cells: 53.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Stomach Adenocarcinoma (TCGA): 2.0" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Colon - Macrophages, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012226, CAB016388, HPA021563, HPA053012" Enhanced Nucleoplasm,Cytosol NA Yes "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 27: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 102: Non-specific - Mixed function" 207 Nucleoplasm Cytosol "CAB012226: , CAB016388: , HPA021563: , HPA053012: " "unprognostic (2.50e-1)" "unprognostic (9.01e-3)" "unprognostic (6.08e-2)" "unprognostic (8.51e-2)" "unprognostic (8.08e-2)" "unprognostic (3.71e-1)" "unprognostic (2.80e-2)" "unprognostic (1.58e-2)" "unprognostic (5.44e-1)" POLR2B RPB2 ENSG00000047315 "RNA polymerase II subunit B" P30876 4 56977722-57031158 "Enzymes, Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Hydrolase, Nucleotidyltransferase, RNA-directed RNA polymerase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037506 Approved Supported Nucleoplasm NA NA 4500 "Cluster 5: Non-specific - Cell proliferation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 228 Nucleoplasm "HPA037506: " "unprognostic (1.41e-1)" "unprognostic (4.08e-3)" "unprognostic (1.22e-1)" "unprognostic (4.95e-3)" "unprognostic (2.59e-2)" "unprognostic (8.37e-2)" "unprognostic (1.12e-1)" "unprognostic (1.14e-2)" "unprognostic (4.06e-2)" "potential prognostic unfavorable (1.19e-4)" "potential prognostic favorable (1.87e-7)" "unprognostic (6.27e-3)" "unprognostic (2.23e-1)" "unprognostic (6.49e-3)" "unprognostic (2.48e-1)" "unprognostic (1.22e-1)" "unprognostic (1.04e-1)" "unprognostic (4.07e-1)" "unprognostic (3.12e-2)" "unprognostic (1.75e-1)" "unprognostic (3.43e-2)" "unprognostic (1.63e-2)" "unprognostic (5.06e-2)" "unprognostic (2.12e-1)" "unprognostic (3.17e-3)" "unprognostic (9.02e-2)" "unprognostic (5.17e-2)" "unprognostic (1.60e-1)" "unprognostic (3.45e-1)" "unprognostic (6.97e-2)" "unprognostic (1.42e-2)" POLR2C RPB3 ENSG00000102978 "RNA polymerase II subunit C" P19387 16 57462660-57472009 "Essential proteins, Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040919, HPA041826" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 41: Basophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 97: Non-specific - Cellular respiration" 164 Nucleoplasm Cytosol "HPA040919: , HPA041826: " "unprognostic (2.36e-1)" "unprognostic (1.06e-2)" "unprognostic (1.27e-2)" "unprognostic (8.19e-3)" "unprognostic (1.33e-1)" "unprognostic (1.36e-1)" "unprognostic (1.09e-1)" "unprognostic (5.21e-2)" "potential prognostic unfavorable (1.94e-4)" "unprognostic (1.95e-1)" "potential prognostic favorable (1.57e-9)" "unprognostic (8.39e-3)" "unprognostic (7.70e-3)" "unprognostic (2.03e-1)" "unprognostic (3.92e-1)" "unprognostic (5.22e-2)" "unprognostic (4.25e-2)" "unprognostic (1.99e-1)" "unprognostic (4.52e-3)" "unprognostic (3.24e-1)" "unprognostic (4.95e-2)" "unprognostic (2.12e-1)" "unprognostic (2.36e-1)" "unprognostic (1.92e-2)" "unprognostic (2.72e-2)" "unprognostic (3.91e-3)" "unprognostic (5.91e-2)" "unprognostic (2.54e-2)" "unprognostic (1.90e-1)" "unprognostic (7.67e-2)" "unprognostic (4.57e-1)" POLR2D RPB4 ENSG00000144231 "RNA polymerase II subunit D" O15514 2 127843553-127858155 "Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 69.5" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 62.5;Late spermatids: 129.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034694, HPA046092" Approved Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 39: Testis - Nuclear processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 127 "Nucleoplasm, Nuclear speckles" Cytosol "HPA034694: , HPA046092: " "unprognostic (1.16e-1)" "unprognostic (2.13e-2)" "unprognostic (1.69e-1)" "unprognostic (2.04e-2)" "unprognostic (3.15e-1)" "unprognostic (9.69e-2)" "unprognostic (2.17e-1)" "unprognostic (9.48e-2)" "unprognostic (3.94e-2)" "unprognostic (9.36e-3)" "unprognostic (4.18e-3)" "unprognostic (3.65e-2)" "potential prognostic unfavorable (1.00e-4)" "potential prognostic unfavorable (7.05e-5)" "unprognostic (1.02e-3)" "unprognostic (3.05e-3)" "unprognostic (1.94e-3)" "unprognostic (3.03e-1)" "unprognostic (5.47e-2)" "unprognostic (2.43e-1)" "unprognostic (8.07e-2)" "unprognostic (1.25e-2)" "unprognostic (1.57e-2)" "unprognostic (6.04e-2)" "unprognostic (2.43e-2)" "unprognostic (9.96e-2)" "unprognostic (5.82e-2)" "unprognostic (1.76e-1)" "unprognostic (2.87e-1)" "unprognostic (3.71e-2)" "unprognostic (7.10e-2)" POLR2E "hRPB25, hsRPB5, RPABC1, RPB5, XAP4" ENSG00000099817 "RNA polymerase II, I and III subunit E" P19388 19 1086574-1095380 "Essential proteins, Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" "Host-virus interaction, Transcription" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal basal cells: 335.1;Esophageal suprabasal cells: 338.3;Extravillous trophoblasts: 297.4;Hofbauer cells: 344.8;Migrating cytotrophoblasts: 321.0;Oocytes: 478.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063030, HPA068992" Supported Supported Nucleoplasm NA NA 10000 "Cluster 29: Non-specific - Unknown function" "Cluster 36: Brain & Liver - Signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 23: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 318 Nucleoplasm "HPA063030: , HPA068992: " "unprognostic (6.81e-2)" "unprognostic (3.69e-1)" "unprognostic (1.42e-2)" "unprognostic (8.61e-2)" "unprognostic (4.22e-2)" "unprognostic (3.33e-1)" "unprognostic (1.63e-2)" "unprognostic (3.20e-1)" "unprognostic (5.83e-2)" "unprognostic (7.46e-2)" "potential prognostic favorable (7.63e-8)" "unprognostic (2.09e-2)" "potential prognostic favorable (1.11e-4)" "unprognostic (1.52e-1)" "potential prognostic unfavorable (5.86e-5)" "unprognostic (3.64e-1)" "unprognostic (5.77e-2)" "unprognostic (2.02e-1)" "unprognostic (6.92e-2)" "unprognostic (3.00e-2)" "unprognostic (1.70e-1)" "unprognostic (6.83e-2)" "unprognostic (2.74e-1)" "unprognostic (2.52e-1)" "unprognostic (2.34e-1)" "unprognostic (4.03e-2)" "unprognostic (1.30e-1)" "unprognostic (1.30e-1)" "unprognostic (1.62e-2)" "unprognostic (3.95e-1)" "unprognostic (4.89e-3)" POLR2F "HRBP14.4, RPB6" ENSG00000100142 "RNA polymerase II, I and III subunit F" P61218 22 37952607-38041915 "Essential proteins, Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 377.4;Oligodendrocytes: 628.1" "Group enriched" "Detected in all" 9 "committed oligodendrocyte precursor: 496.5;oligodendrocyte: 726.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000827, CAB009882" Supported Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 66: Non-specific - Mitochondria" "Cluster 80: Oligodendrocytes - Myelination" 178 "Nucleoplasm, Nucleoli fibrillar center" "CAB009882: , HPA000827: " "unprognostic (5.07e-2)" "unprognostic (3.68e-2)" "unprognostic (2.30e-2)" "unprognostic (2.91e-2)" "unprognostic (2.03e-2)" "unprognostic (2.55e-1)" "unprognostic (3.85e-2)" "potential prognostic favorable (2.44e-4)" "unprognostic (1.26e-2)" "potential prognostic unfavorable (3.96e-8)" "unprognostic (7.34e-2)" "unprognostic (1.01e-1)" "unprognostic (7.94e-2)" "unprognostic (4.05e-3)" "unprognostic (3.95e-3)" "unprognostic (2.34e-2)" "unprognostic (1.45e-1)" "unprognostic (1.04e-2)" "unprognostic (5.23e-2)" "unprognostic (1.58e-2)" "unprognostic (1.47e-1)" "unprognostic (3.09e-2)" "unprognostic (1.49e-1)" "unprognostic (6.12e-2)" "unprognostic (4.55e-2)" "unprognostic (5.01e-2)" "unprognostic (2.54e-1)" "unprognostic (1.79e-1)" "unprognostic (4.04e-2)" "unprognostic (2.74e-1)" "unprognostic (2.05e-1)" POLR2G "hRPB19, hsRPB7, RPB7" ENSG00000168002 "RNA polymerase II subunit G" P62487 11 62761565-62766710 "Essential proteins, Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" Transcription RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 268.6;Decidual stromal cells: 197.9;Hofbauer cells: 250.1;Platelets: 265.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053000 Approved Supported Nucleoplasm NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 121 Nucleoplasm "HPA053000: " "unprognostic (3.26e-3)" "unprognostic (1.21e-1)" "unprognostic (1.49e-2)" "unprognostic (3.54e-1)" "unprognostic (2.16e-1)" "unprognostic (5.21e-2)" "unprognostic (3.19e-1)" "unprognostic (2.67e-1)" "potential prognostic unfavorable (5.76e-4)" "unprognostic (1.47e-2)" "unprognostic (5.07e-3)" "unprognostic (7.07e-2)" "unprognostic (1.23e-1)" "validated prognostic unfavorable (6.93e-6)" "validated prognostic unfavorable (3.15e-4)" "unprognostic (1.33e-2)" "unprognostic (1.62e-2)" "unprognostic (9.65e-2)" "unprognostic (3.44e-2)" "unprognostic (2.70e-2)" "unprognostic (1.28e-2)" "unprognostic (3.38e-2)" "unprognostic (3.87e-1)" "unprognostic (3.06e-2)" "unprognostic (8.01e-2)" "unprognostic (1.99e-1)" "unprognostic (3.41e-3)" "unprognostic (1.27e-1)" "unprognostic (3.25e-2)" "unprognostic (3.42e-1)" "unprognostic (1.56e-1)" POLR2H RPB8 ENSG00000163882 "RNA polymerase II, I and III subunit H" P52434 3 184361710-184368596 "Essential proteins, Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" Transcription DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric progenitor cells: 228.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037745, HPA055813" Supported Uncertain Nucleoplasm NA NA 31000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 60: Stomach - Digestion" "Cluster 15: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 17: Non-specific - RNA processing" 143 Nucleoplasm "HPA037745: , HPA055813: " "unprognostic (2.27e-1)" "unprognostic (6.42e-3)" "unprognostic (8.48e-2)" "unprognostic (3.58e-2)" "unprognostic (3.38e-1)" "unprognostic (9.79e-2)" "unprognostic (5.62e-2)" "unprognostic (5.15e-2)" "unprognostic (1.75e-2)" "potential prognostic unfavorable (1.20e-4)" "unprognostic (1.15e-2)" "unprognostic (1.71e-2)" "unprognostic (2.54e-2)" "validated prognostic unfavorable (2.23e-5)" "validated prognostic unfavorable (6.56e-4)" "potential prognostic unfavorable (7.62e-4)" "unprognostic (3.83e-3)" "unprognostic (3.77e-3)" "unprognostic (4.69e-3)" "unprognostic (4.58e-3)" "unprognostic (1.05e-1)" "unprognostic (1.99e-3)" "potential prognostic unfavorable (6.72e-4)" "unprognostic (1.01e-3)" "unprognostic (3.99e-2)" "unprognostic (2.45e-2)" "unprognostic (1.28e-1)" "unprognostic (1.19e-1)" "unprognostic (2.80e-1)" "unprognostic (2.35e-1)" "unprognostic (1.02e-1)" POLR2I "hRPB14.5, RPB9" ENSG00000105258 "RNA polymerase II subunit I" P36954 19 36113709-36115213 "Essential proteins, Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 1108.9;Late primary spermatocytes: 1112.5;Late spermatids: 3808.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035632, HPA045156" Uncertain Enhanced Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 76 Nucleoplasm "HPA035632: , HPA045156: " "unprognostic (2.45e-1)" "unprognostic (1.34e-2)" "unprognostic (1.06e-1)" "unprognostic (1.13e-2)" "unprognostic (1.36e-1)" "unprognostic (3.72e-1)" "unprognostic (8.75e-2)" "unprognostic (8.29e-2)" "unprognostic (1.95e-2)" "unprognostic (1.89e-2)" "unprognostic (3.47e-1)" "unprognostic (1.44e-1)" "unprognostic (4.05e-2)" "unprognostic (4.56e-3)" "unprognostic (1.66e-2)" "unprognostic (2.24e-2)" "unprognostic (6.16e-2)" "unprognostic (6.17e-3)" "unprognostic (1.65e-2)" "unprognostic (3.75e-1)" "unprognostic (1.49e-2)" "unprognostic (4.56e-2)" "unprognostic (6.52e-2)" "unprognostic (1.09e-1)" "unprognostic (4.13e-2)" "unprognostic (1.94e-1)" "unprognostic (6.10e-2)" "unprognostic (4.89e-2)" "unprognostic (5.79e-2)" "unprognostic (3.30e-1)" "unprognostic (7.64e-2)" POLR2J "hRPB14, POLR2J1, RPB11, RPB11A, RPB11m" ENSG00000005075 "RNA polymerase II subunit J" P52435 7 102473128-102478922 "Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 401.7;Oocytes: 635.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA046970 Approved Nucleoplasm NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 147 Nucleoplasm "HPA046970: " "unprognostic (1.12e-1)" "unprognostic (2.10e-1)" "unprognostic (8.66e-2)" "potential prognostic favorable (2.50e-4)" "unprognostic (4.56e-2)" "unprognostic (2.21e-1)" "unprognostic (2.82e-3)" "unprognostic (1.96e-2)" "unprognostic (1.82e-2)" "unprognostic (2.75e-2)" "potential prognostic unfavorable (1.83e-4)" "unprognostic (1.96e-2)" "unprognostic (3.08e-1)" "validated prognostic unfavorable (8.37e-4)" "validated prognostic unfavorable (2.73e-5)" "unprognostic (3.36e-2)" "unprognostic (2.06e-2)" "unprognostic (5.80e-2)" "unprognostic (1.44e-1)" "unprognostic (2.94e-2)" "unprognostic (2.32e-1)" "unprognostic (8.99e-2)" "unprognostic (1.32e-2)" "unprognostic (7.75e-2)" "unprognostic (4.27e-2)" "unprognostic (1.70e-1)" "unprognostic (1.52e-2)" "unprognostic (1.65e-1)" "unprognostic (7.40e-2)" "unprognostic (9.90e-2)" "unprognostic (1.28e-1)" POLR2J2 RPB11b1 ENSG00000228049 "RNA polymerase II subunit J2" Q9GZM3 7 102665368-102671663 "Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA046970 Approved Nucleoplasm NA NA "Cluster 32: Basophils - Transcription" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 39: Non-specific - Transcription" Nucleoplasm "HPA046970: " "unprognostic (6.29e-2)" "unprognostic (6.74e-2)" "unprognostic (2.28e-1)" "unprognostic (5.06e-3)" "unprognostic (1.71e-1)" "unprognostic (1.30e-1)" "unprognostic (7.08e-2)" "unprognostic (3.71e-2)" "unprognostic (6.89e-3)" "unprognostic (1.27e-1)" "unprognostic (2.43e-1)" "unprognostic (8.12e-3)" "unprognostic (5.62e-2)" "unprognostic (4.51e-2)" "unprognostic (3.58e-1)" "unprognostic (5.58e-2)" "unprognostic (2.57e-1)" "unprognostic (3.95e-1)" "unprognostic (2.62e-2)" "unprognostic (5.35e-1)" "unprognostic (1.16e-1)" "unprognostic (2.20e-1)" "unprognostic (5.31e-2)" "unprognostic (1.05e-1)" "unprognostic (1.10e-1)" "unprognostic (2.13e-1)" "unprognostic (2.15e-3)" "unprognostic (1.05e-1)" POLR2J3 ENSG00000168255 "RNA polymerase II subunit J3" 7 102537918-102572653 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 1.0;Bergmann glia: 1.2;Ependymal cells: 1.0;Esophageal apical cells: 2.6;Ocular epithelial cells: 1.2;Oligodendrocytes: 1.1" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA011403, HPA046970" Uncertain Approved Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 98: Neurons - Neurotransmission & signaling" Nucleoplasm "HPA011403: , HPA046970: " "unprognostic (2.66e-1)" "unprognostic (8.85e-2)" "unprognostic (2.44e-1)" "unprognostic (1.24e-1)" "unprognostic (2.15e-1)" "unprognostic (1.66e-3)" "unprognostic (2.70e-1)" "unprognostic (2.98e-3)" "unprognostic (2.79e-1)" "unprognostic (4.45e-2)" "unprognostic (1.88e-2)" "unprognostic (9.99e-2)" "unprognostic (3.28e-1)" "unprognostic (2.53e-1)" "unprognostic (3.52e-3)" "unprognostic (2.99e-1)" "unprognostic (5.38e-2)" "unprognostic (2.06e-2)" "unprognostic (2.96e-1)" "unprognostic (2.49e-2)" "unprognostic (5.08e-2)" "unprognostic (2.82e-3)" "unprognostic (2.16e-2)" "unprognostic (6.26e-2)" "unprognostic (2.10e-1)" "unprognostic (1.37e-1)" POLR2J3 ENSG00000285437 "RNA polymerase II subunit J3" 7 102562133-102572583 "Predicted intracellular proteins, RNA polymerase related proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Epididymal principal cells: 1.6;Foveolar cells: 1.5;Gastric chief cells: 1.1;Mucous neck cells: 1.2;Parietal cells: 1.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA046970 Approved Nucleoplasm NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 39: Non-specific - Transcription" "Cluster 15: Non-specific - Protein processing" Nucleoplasm "HPA046970: " "unprognostic (4.03e-2)" "unprognostic (4.30e-2)" "unprognostic (6.70e-2)" "unprognostic (3.60e-1)" "unprognostic (1.04e-1)" "unprognostic (2.99e-1)" "unprognostic (1.12e-1)" "unprognostic (4.84e-2)" "unprognostic (2.91e-2)" "unprognostic (5.58e-2)" "potential prognostic unfavorable (1.18e-4)" "unprognostic (1.58e-2)" "unprognostic (3.29e-1)" "unprognostic (1.17e-1)" "unprognostic (4.90e-2)" "unprognostic (1.48e-2)" "unprognostic (4.40e-1)" "unprognostic (3.18e-1)" "unprognostic (2.46e-1)" "unprognostic (1.92e-1)" "unprognostic (2.76e-3)" "unprognostic (4.82e-2)" "unprognostic (1.20e-1)" "unprognostic (4.77e-1)" "unprognostic (2.08e-1)" "unprognostic (1.07e-2)" POLR2K "RPB10alpha, RPB12" ENSG00000147669 "RNA polymerase II, I and III subunit K" P53803 8 100150623-100154003 "Essential proteins, Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric progenitor cells: 344.8;Oocytes: 396.0;Parietal cells: 433.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047477 Supported "Nucleoli fibrillar center" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 76: Non-specific - Metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 40: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 184 "Nucleoli fibrillar center" "HPA047477: " "unprognostic (3.10e-2)" "unprognostic (2.55e-3)" "unprognostic (2.09e-2)" "unprognostic (2.57e-1)" "unprognostic (1.64e-1)" "unprognostic (6.03e-2)" "unprognostic (1.01e-2)" "unprognostic (1.11e-1)" "unprognostic (5.92e-2)" "unprognostic (4.63e-3)" "unprognostic (4.08e-3)" "unprognostic (2.64e-1)" "unprognostic (6.09e-2)" "unprognostic (2.62e-3)" "unprognostic (7.65e-3)" "potential prognostic unfavorable (4.70e-4)" "unprognostic (2.33e-1)" "unprognostic (6.92e-2)" "unprognostic (5.71e-1)" "unprognostic (1.81e-1)" "unprognostic (7.86e-3)" "unprognostic (1.24e-1)" "potential prognostic unfavorable (3.36e-4)" "unprognostic (1.87e-1)" "unprognostic (4.49e-1)" "unprognostic (2.30e-2)" "unprognostic (6.05e-2)" "unprognostic (4.75e-2)" "unprognostic (1.63e-1)" "unprognostic (7.66e-2)" "unprognostic (1.15e-1)" POLR2L "hRPB7.6, hsRPB10b, RBP10, RPABC5, RPB10beta, RPB7.6" ENSG00000177700 "RNA polymerase II, I and III subunit L" P62875 11 837356-842529 "Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 1884.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA073614 Supported Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 36: Choroid plexus - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 147 Nucleoplasm "HPA073614: " "unprognostic (1.07e-3)" "unprognostic (3.30e-2)" "unprognostic (1.01e-1)" "unprognostic (6.20e-3)" "unprognostic (2.22e-1)" "unprognostic (2.65e-2)" "unprognostic (6.03e-2)" "unprognostic (7.03e-3)" "unprognostic (4.54e-2)" "unprognostic (2.62e-1)" "unprognostic (4.02e-2)" "unprognostic (9.16e-2)" "unprognostic (1.12e-3)" "potential prognostic unfavorable (1.75e-6)" "unprognostic (1.11e-2)" "unprognostic (1.90e-1)" "unprognostic (2.52e-2)" "unprognostic (1.38e-1)" "unprognostic (1.95e-1)" "unprognostic (4.06e-2)" "unprognostic (1.23e-1)" "unprognostic (1.21e-2)" "unprognostic (1.99e-1)" "unprognostic (1.37e-1)" "unprognostic (2.18e-1)" "unprognostic (3.86e-2)" "unprognostic (2.88e-1)" "unprognostic (5.03e-3)" "unprognostic (1.09e-1)" "unprognostic (3.08e-3)" "unprognostic (1.47e-1)" POLR2M "Gdown, Gdown1, GRINL1A" ENSG00000255529 "RNA polymerase II subunit M" "P0CAP2, Q6EEV4" 15 57706695-57782762 "Essential proteins, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 64.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068141 Approved Nucleoplasm NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 51: Secretory epithelial cells - Mixed function" 27 Nucleoplasm "HPA068141: " "unprognostic (3.51e-2)" "unprognostic (1.29e-1)" "unprognostic (2.22e-1)" "unprognostic (1.11e-1)" "unprognostic (2.51e-1)" "unprognostic (6.68e-2)" "unprognostic (1.09e-1)" "unprognostic (7.22e-2)" "unprognostic (7.94e-2)" "validated prognostic favorable (6.28e-6)" "validated prognostic favorable (3.46e-5)" "unprognostic (1.26e-1)" "unprognostic (1.43e-1)" "unprognostic (2.02e-2)" "unprognostic (1.73e-1)" "unprognostic (1.26e-1)" "unprognostic (3.00e-2)" "unprognostic (5.33e-3)" "unprognostic (1.65e-2)" "unprognostic (1.86e-1)" "unprognostic (5.93e-2)" "unprognostic (3.97e-2)" "unprognostic (1.73e-1)" "unprognostic (4.00e-2)" "unprognostic (1.56e-1)" "unprognostic (1.15e-1)" "unprognostic (1.36e-1)" "unprognostic (1.39e-1)" "unprognostic (2.09e-1)" POLR3A "C160, hRPC155, RPC1, RPC155" ENSG00000148606 "RNA polymerase III subunit A" O14802 10 77953148-78029522 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RNA polymerase related proteins" "Antiviral defense, Immunity, Innate immunity, Transcription" "Nucleotidyltransferase, Transferase" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Corticotrophs: 129.9;Somatotrophs: 124.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037926 Uncertain Supported Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 24: Non-specific - Transcription" "Cluster 24: Neurons - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 106 Nucleoplasm "HPA037926: " "unprognostic (4.08e-2)" "unprognostic (1.28e-2)" "unprognostic (5.30e-2)" "unprognostic (1.29e-2)" "unprognostic (3.54e-1)" "unprognostic (7.20e-2)" "unprognostic (2.10e-1)" "potential prognostic favorable (3.92e-8)" "unprognostic (1.23e-1)" "unprognostic (4.36e-2)" "unprognostic (3.38e-2)" "unprognostic (1.69e-1)" "unprognostic (1.69e-1)" "potential prognostic unfavorable (7.06e-6)" "unprognostic (1.04e-3)" "unprognostic (7.54e-2)" "unprognostic (2.20e-3)" "unprognostic (7.81e-3)" "unprognostic (3.62e-1)" "unprognostic (3.28e-2)" "unprognostic (2.91e-3)" "unprognostic (7.72e-2)" "unprognostic (1.16e-3)" "unprognostic (4.16e-2)" "unprognostic (3.93e-2)" "unprognostic (8.49e-2)" "unprognostic (2.02e-1)" "unprognostic (1.42e-1)" "unprognostic (1.31e-1)" "unprognostic (7.81e-2)" "unprognostic (1.05e-1)" POLR3B "C128, FLJ10388, RPC2" ENSG00000013503 "RNA polymerase III subunit B" Q9NW08 12 106357748-106510198 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, RNA polymerase related proteins" "Antiviral defense, Immunity, Innate immunity, Transcription" "Nucleotidyltransferase, Transferase" "Charcot-Marie-Tooth disease, Disease variant, Leukodystrophy, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 93.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Skin - Keratinocyte (other), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036466 Supported Approved "Nuclear speckles" NA NA "Cluster 32: Basophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 106 "Nuclear speckles" "HPA036466: " "unprognostic (2.35e-1)" "unprognostic (3.29e-2)" "unprognostic (1.71e-1)" "potential prognostic unfavorable (3.40e-4)" "unprognostic (6.65e-2)" "unprognostic (4.44e-2)" "unprognostic (5.75e-2)" "unprognostic (2.46e-2)" "unprognostic (8.03e-2)" "potential prognostic unfavorable (4.71e-4)" "potential prognostic favorable (5.09e-4)" "unprognostic (1.12e-1)" "unprognostic (1.55e-1)" "unprognostic (5.13e-2)" "unprognostic (2.82e-2)" "unprognostic (7.13e-2)" "unprognostic (5.18e-2)" "unprognostic (1.82e-1)" "unprognostic (3.81e-2)" "unprognostic (7.61e-2)" "unprognostic (4.45e-3)" "unprognostic (1.93e-1)" "unprognostic (1.96e-2)" "unprognostic (1.62e-1)" "unprognostic (7.18e-2)" "unprognostic (5.39e-2)" "unprognostic (6.61e-2)" "unprognostic (2.09e-1)" "unprognostic (2.45e-1)" "unprognostic (9.90e-2)" "unprognostic (9.14e-2)" POLR3C "C82, RPC3, RPC62" ENSG00000186141 "RNA polymerase III subunit C" Q9BUI4 1 145824053-145844402 "Essential proteins, Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" "Antiviral defense, Immunity, Innate immunity, Transcription" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Early spermatids: 386.5;Late spermatids: 831.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027508, HPA027516" Uncertain Enhanced Nucleoplasm NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 39: Testis - Nuclear processes" "Cluster 15: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 96 Nucleoplasm "HPA027508: , HPA027516: " "unprognostic (1.03e-1)" "unprognostic (1.96e-1)" "unprognostic (1.72e-1)" "unprognostic (1.14e-1)" "unprognostic (4.27e-2)" "unprognostic (1.25e-1)" "unprognostic (5.89e-2)" "unprognostic (1.98e-3)" "unprognostic (2.06e-1)" "potential prognostic unfavorable (1.99e-4)" "validated prognostic favorable (3.46e-6)" "validated prognostic favorable (4.44e-4)" "unprognostic (1.09e-1)" "potential prognostic unfavorable (5.09e-5)" "unprognostic (3.96e-2)" "unprognostic (1.05e-1)" "unprognostic (3.32e-3)" "unprognostic (1.47e-1)" "unprognostic (4.93e-1)" "unprognostic (4.27e-2)" "unprognostic (6.91e-2)" "unprognostic (2.06e-1)" "unprognostic (1.46e-1)" "unprognostic (1.43e-1)" "unprognostic (2.32e-2)" "unprognostic (1.26e-1)" "unprognostic (1.29e-1)" "unprognostic (1.55e-1)" "unprognostic (4.34e-2)" "unprognostic (8.53e-2)" "unprognostic (1.83e-1)" POLR3D "BN51T, C53, RPC4, TSBN51" ENSG00000168495 "RNA polymerase III subunit D" P05423 8 22245133-22254601 "Essential proteins, Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" "Antiviral defense, Immunity, Innate immunity, Transcription" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 74.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA061331, HPA067875, HPA068461, HPA069089" Supported Enhanced Nucleoplasm NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 40: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 83 Nucleoplasm "HPA061331: , HPA067875: , HPA068461: , HPA069089: " "unprognostic (1.11e-2)" "unprognostic (1.85e-1)" "unprognostic (1.43e-3)" "unprognostic (2.62e-1)" "unprognostic (3.30e-1)" "unprognostic (1.14e-1)" "unprognostic (2.70e-1)" "unprognostic (1.06e-2)" "unprognostic (1.27e-1)" "unprognostic (2.99e-2)" "unprognostic (1.99e-2)" "unprognostic (1.12e-2)" "unprognostic (5.11e-2)" "unprognostic (1.07e-3)" "unprognostic (6.23e-2)" "unprognostic (2.76e-2)" "unprognostic (2.11e-3)" "unprognostic (1.60e-1)" "unprognostic (6.95e-2)" "unprognostic (3.94e-1)" "unprognostic (4.85e-3)" "unprognostic (7.62e-2)" "unprognostic (1.27e-2)" "unprognostic (4.14e-1)" "unprognostic (1.27e-1)" "unprognostic (2.29e-3)" "unprognostic (3.26e-1)" "unprognostic (6.78e-2)" "unprognostic (1.64e-1)" "unprognostic (2.80e-2)" "unprognostic (9.32e-2)" POLR3E "C37, FLJ10509, RPC5, SIN" ENSG00000058600 "RNA polymerase III subunit E" Q9NVU0 16 22297375-22335101 "Essential proteins, Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" "Antiviral defense, Immunity, Innate immunity, Transcription" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 55.6" "Cell type enhanced" "Detected in many" "Astrocytes: 19.2;Bergmann glia: 21.0;Brain excitatory neurons: 16.9;Brain inhibitory neurons: 17.3;Choroid plexus epithelial cells: 48.5;Distal convoluted tubule cells: 25.9;Ependymal cells: 22.8;Loop of henle epithelial cells: 18.8;Microglia: 16.9;Oligodendrocyte progenitor cells: 22.2;Oligodendrocytes: 22.1;Papillary tip epithelial cells: 21.5;Podocytes: 25.3;Proximal tubule cells: 23.0;Renal collecting duct intercalated cells: 31.0;Renal collecting duct principal cells: 28.3;Renal connecting tubule cells: 25.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041419, HPA041477" Approved Enhanced Nucleoplasm Yes No "Cluster 16: Non-specific - Cell proliferation" "Cluster 24: Non-specific - Transcription" "Cluster 44: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 102: Non-specific - Mixed function" 99 Nucleoplasm "HPA041419: , HPA041477: " "unprognostic (2.01e-1)" "unprognostic (2.51e-1)" "unprognostic (3.39e-2)" "unprognostic (5.41e-2)" "unprognostic (2.02e-1)" "unprognostic (2.51e-1)" "unprognostic (1.73e-1)" "potential prognostic favorable (2.55e-4)" "unprognostic (3.08e-1)" "unprognostic (2.84e-1)" "potential prognostic favorable (6.69e-7)" "unprognostic (1.36e-1)" "unprognostic (1.22e-1)" "unprognostic (1.89e-3)" "unprognostic (2.79e-2)" "unprognostic (1.05e-2)" "unprognostic (4.17e-2)" "unprognostic (1.13e-2)" "unprognostic (1.49e-1)" "unprognostic (1.65e-1)" "unprognostic (2.46e-1)" "unprognostic (8.60e-2)" "unprognostic (1.98e-2)" "unprognostic (1.61e-1)" "unprognostic (9.50e-3)" "unprognostic (1.22e-1)" "unprognostic (3.80e-2)" "unprognostic (3.07e-1)" "unprognostic (1.71e-1)" "unprognostic (6.25e-2)" "unprognostic (2.37e-1)" POLR3F "C34, RPC39, RPC6" ENSG00000132664 "RNA polymerase III subunit F" Q9H1D9 20 18466878-18484648 "Disease related genes, Essential proteins, Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" "Antiviral defense, Immunity, Innate immunity, Transcription" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 63.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049441, HPA050173, HPA072298" Uncertain Approved Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 27: Cerebellum - Synaptic function" "Cluster 31: Non-specific - Transcription" "Cluster 3: Rhabdoid - Membrane components" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" 83 Nucleoplasm "HPA049441: , HPA050173: , HPA072298: " "unprognostic (1.61e-2)" "unprognostic (9.67e-2)" "unprognostic (6.91e-2)" "unprognostic (1.35e-2)" "unprognostic (7.01e-3)" "unprognostic (2.61e-1)" "unprognostic (2.68e-1)" "unprognostic (2.19e-2)" "unprognostic (2.90e-1)" "unprognostic (1.15e-3)" "potential prognostic favorable (6.21e-4)" "unprognostic (1.06e-1)" "unprognostic (1.07e-1)" "potential prognostic unfavorable (2.87e-8)" "unprognostic (6.03e-2)" "unprognostic (2.40e-1)" "unprognostic (3.25e-1)" "unprognostic (3.06e-2)" "unprognostic (3.14e-1)" "unprognostic (3.05e-1)" "unprognostic (2.28e-1)" "unprognostic (1.90e-2)" "unprognostic (3.25e-2)" "unprognostic (1.35e-1)" "unprognostic (6.17e-2)" "unprognostic (2.66e-3)" "unprognostic (1.69e-1)" "unprognostic (1.52e-1)" "unprognostic (3.28e-1)" "unprognostic (1.88e-3)" "unprognostic (2.62e-1)" POLR3G "C31, RPC32, RPC7" ENSG00000113356 "RNA polymerase III subunit G" O15318 5 90471748-90514557 "Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" "Antiviral defense, Immunity, Innate immunity, Transcription" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 67.5;Cone photoreceptor cells: 60.0;Corticotrophs: 38.3;Differentiating spermatogonia: 45.7;Fibro-adipogenic progenitors: 35.9;Oligodendrocytes: 46.8;Oocytes: 50.7;Other brain neurons: 45.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Testis - Spermatogonia" "CAB010109, HPA052658, HPA074330" Enhanced Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 32: Basophils - Transcription" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 72: Neuronal - Signal transduction" "Cluster 109: Neurons - Neuronal signaling" 55 Nucleoplasm "Nuclear bodies, Cytosol" "CAB010109: , HPA052658: , HPA074330: " "potential prognostic unfavorable (8.33e-4)" "unprognostic (1.81e-1)" "unprognostic (1.27e-1)" "unprognostic (1.30e-1)" "unprognostic (1.95e-2)" "unprognostic (9.48e-2)" "unprognostic (2.97e-1)" "unprognostic (5.35e-3)" "unprognostic (3.20e-2)" "potential prognostic unfavorable (3.62e-7)" "unprognostic (1.54e-2)" "unprognostic (1.79e-3)" "potential prognostic unfavorable (3.39e-4)" "potential prognostic unfavorable (5.11e-5)" "unprognostic (6.96e-3)" "potential prognostic unfavorable (3.11e-4)" "unprognostic (8.07e-2)" "unprognostic (2.52e-2)" "unprognostic (1.02e-1)" "unprognostic (1.62e-2)" "unprognostic (2.04e-1)" "unprognostic (2.10e-3)" "potential prognostic unfavorable (1.74e-5)" "unprognostic (1.28e-1)" "unprognostic (1.01e-1)" "unprognostic (1.78e-1)" "unprognostic (2.23e-1)" "unprognostic (8.00e-2)" "unprognostic (4.08e-2)" "unprognostic (8.05e-3)" "unprognostic (2.05e-1)" POLR3GL "flj32422, MGC3200" ENSG00000121851 "RNA polymerase III subunit GL" Q9BT43 1 145964690-145978848 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" HPA027288 Uncertain NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 63 "HPA027288: " "unprognostic (4.39e-2)" "unprognostic (6.20e-3)" "unprognostic (2.43e-2)" "unprognostic (6.27e-2)" "unprognostic (2.86e-1)" "unprognostic (2.22e-1)" "unprognostic (1.29e-1)" "unprognostic (6.97e-3)" "unprognostic (2.40e-1)" "unprognostic (1.38e-3)" "potential prognostic favorable (9.18e-4)" "unprognostic (1.57e-2)" "unprognostic (1.47e-1)" "unprognostic (1.08e-1)" "unprognostic (2.05e-1)" "unprognostic (1.42e-1)" "unprognostic (2.09e-1)" "unprognostic (1.45e-2)" "unprognostic (9.29e-2)" "unprognostic (1.03e-1)" "unprognostic (1.19e-2)" "unprognostic (6.22e-2)" "unprognostic (2.42e-2)" "unprognostic (7.32e-2)" "unprognostic (9.67e-3)" "unprognostic (9.77e-2)" "unprognostic (9.07e-2)" "unprognostic (9.22e-2)" "unprognostic (1.44e-1)" "unprognostic (2.24e-1)" "unprognostic (3.26e-2)" POLR3H "C25, KIAA1665, RPC8" ENSG00000100413 "RNA polymerase III subunit H" Q9Y535 22 41525799-41544606 "Essential proteins, Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" "Antiviral defense, Immunity, Innate immunity, Transcription" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 168.7;Late spermatids: 300.8;Oocytes: 110.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Minor Salivary Gland - Minor salivary glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046787 Approved Supported Nucleoplasm,Vesicles,Centrosome NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 78: Brain - Neuronal signaling" "Cluster 44: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 56 Nucleoplasm "Vesicles, Centrosome" "HPA046787: " "unprognostic (1.66e-1)" "unprognostic (9.67e-2)" "unprognostic (4.48e-2)" "unprognostic (4.10e-2)" "unprognostic (1.35e-2)" "unprognostic (6.20e-2)" "unprognostic (1.07e-1)" "unprognostic (1.21e-2)" "unprognostic (1.08e-1)" "unprognostic (5.48e-2)" "potential prognostic favorable (4.29e-4)" "unprognostic (2.30e-1)" "unprognostic (1.18e-1)" "potential prognostic unfavorable (1.56e-4)" "unprognostic (1.08e-3)" "unprognostic (1.04e-2)" "unprognostic (2.94e-2)" "unprognostic (4.95e-2)" "potential prognostic favorable (2.00e-4)" "unprognostic (4.25e-2)" "unprognostic (3.29e-1)" "unprognostic (2.90e-2)" "unprognostic (8.24e-2)" "unprognostic (1.22e-1)" "unprognostic (3.39e-2)" "unprognostic (1.18e-2)" "unprognostic (8.20e-2)" "unprognostic (1.47e-2)" "unprognostic (1.30e-1)" "unprognostic (1.29e-1)" "unprognostic (5.35e-3)" POLR3K "C11, RPC11" ENSG00000161980 "RNA polymerase III subunit K" Q9Y2Y1 16 46407-53608 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" "Antiviral defense, Immunity, Innate immunity, Transcription" "Disease variant, Leukodystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 75.5;Gastric progenitor cells: 88.4;Megakaryocytes: 74.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005891 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 81 Nucleoplasm Cytosol "HPA005891: " "unprognostic (3.68e-2)" "unprognostic (4.21e-2)" "unprognostic (2.40e-2)" "unprognostic (3.01e-1)" "unprognostic (1.24e-1)" "unprognostic (3.77e-3)" "unprognostic (2.46e-1)" "unprognostic (3.77e-1)" "unprognostic (2.29e-1)" "unprognostic (2.00e-2)" "unprognostic (7.23e-2)" "unprognostic (3.59e-1)" "unprognostic (1.45e-1)" "unprognostic (2.71e-3)" "potential prognostic unfavorable (5.18e-5)" "unprognostic (8.03e-2)" "unprognostic (3.52e-3)" "unprognostic (8.78e-3)" "unprognostic (1.33e-2)" "unprognostic (1.48e-1)" "unprognostic (1.31e-1)" "unprognostic (2.35e-2)" "unprognostic (1.65e-1)" "unprognostic (1.52e-1)" "unprognostic (1.56e-1)" "unprognostic (2.75e-1)" "unprognostic (8.94e-2)" "unprognostic (3.97e-2)" "unprognostic (1.14e-2)" "unprognostic (6.19e-2)" "unprognostic (1.37e-1)" POLRMT "APOLMT, h-mtRPOL, MTRNAP, MTRPOL" ENSG00000099821 "RNA polymerase mitochondrial" O00411 19 617221-633537 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Transcription "Nucleotidyltransferase, Transferase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 91.8;Late primary spermatocytes: 54.2;Late spermatids: 131.1;Undifferentiated spermatogonia: 107.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006366 Uncertain Supported Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 67: Testis - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 23: Non-specific - Transcription" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 37 Mitochondria "HPA006366: " "unprognostic (6.95e-2)" "unprognostic (1.22e-1)" "unprognostic (5.12e-3)" "potential prognostic favorable (2.57e-6)" "unprognostic (7.28e-2)" "unprognostic (1.13e-1)" "unprognostic (4.67e-2)" "unprognostic (2.55e-2)" "unprognostic (1.67e-1)" "unprognostic (2.52e-1)" "unprognostic (8.64e-2)" "unprognostic (1.65e-1)" "unprognostic (6.92e-2)" "unprognostic (1.32e-2)" "unprognostic (2.59e-1)" "unprognostic (3.27e-2)" "unprognostic (1.88e-2)" "unprognostic (6.15e-2)" "unprognostic (3.80e-2)" "unprognostic (2.59e-1)" "unprognostic (2.50e-1)" "unprognostic (5.50e-2)" "unprognostic (1.19e-1)" "unprognostic (1.68e-1)" "unprognostic (1.98e-1)" "potential prognostic favorable (4.67e-5)" "unprognostic (8.83e-3)" "unprognostic (2.36e-2)" "unprognostic (1.00e-1)" "unprognostic (1.71e-1)" "unprognostic (9.72e-2)" POM121 "DKFZP586G1822, DKFZP586P2220, KIAA0618, POM121A" ENSG00000196313 "POM121 transmembrane nucleoporin" Q96HA1 7 72879349-72951440 "Metabolic proteins, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 236.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "CAB003710, HPA043809, HPA049817" Approved Enhanced "Nucleoplasm,Nuclear membrane" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 49: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 39: Non-specific - Transcription" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 28 "Nucleoplasm, Nuclear membrane" "CAB003710: , HPA043809: , HPA049817: " "unprognostic (1.76e-1)" "unprognostic (3.25e-1)" "unprognostic (3.50e-1)" "unprognostic (1.99e-1)" "unprognostic (9.39e-2)" "unprognostic (2.24e-1)" "unprognostic (9.55e-2)" "unprognostic (2.15e-2)" "unprognostic (7.96e-2)" "unprognostic (8.45e-2)" "unprognostic (2.99e-3)" "unprognostic (5.58e-2)" "unprognostic (1.73e-1)" "unprognostic (1.21e-1)" "unprognostic (1.94e-2)" "unprognostic (1.33e-2)" "unprognostic (7.97e-2)" "unprognostic (2.84e-1)" "unprognostic (1.65e-2)" "unprognostic (3.68e-2)" "unprognostic (5.70e-2)" "unprognostic (1.86e-1)" "unprognostic (4.13e-2)" "unprognostic (3.32e-2)" "unprognostic (3.94e-2)" "unprognostic (5.68e-2)" "unprognostic (2.96e-1)" "unprognostic (2.02e-1)" "unprognostic (1.97e-1)" "unprognostic (3.45e-3)" "unprognostic (6.36e-2)" POM121C ENSG00000272391 "POM121 transmembrane nucleoporin C" A8CG34 7 75416786-75486299 "Essential proteins, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "HPA043809, HPA049817" Approved Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 61: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 39: Non-specific - Transcription" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 25 "Nucleoplasm, Nuclear membrane" "HPA043809: , HPA049817: " "unprognostic (1.45e-1)" "unprognostic (1.33e-1)" "unprognostic (5.88e-2)" "unprognostic (1.25e-2)" "unprognostic (1.43e-1)" "unprognostic (1.33e-1)" "unprognostic (1.11e-1)" "unprognostic (9.36e-2)" "unprognostic (9.89e-2)" "potential prognostic favorable (3.80e-5)" "unprognostic (1.87e-2)" "unprognostic (9.84e-2)" "unprognostic (7.13e-2)" "unprognostic (1.00e-3)" "unprognostic (7.64e-2)" "unprognostic (1.46e-2)" "unprognostic (2.90e-1)" "unprognostic (3.57e-3)" "unprognostic (7.46e-2)" "unprognostic (2.70e-1)" "unprognostic (2.38e-1)" "unprognostic (9.02e-2)" "unprognostic (9.05e-2)" "unprognostic (1.42e-1)" "unprognostic (2.96e-1)" "unprognostic (1.42e-1)" "unprognostic (3.58e-3)" "unprognostic (3.36e-2)" POM121L12 DKFZp564N2472 ENSG00000221900 "POM121 transmembrane nucleoporin like 12" Q8N7R1 7 53035633-53036925 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 125 "testis: 12.4" "Cell type enriched" "Detected in some" 10 "Late primary spermatocytes: 33.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" HPA027836 Enhanced NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" "HPA027836: " POM121L2 POM121-L ENSG00000158553 "POM121 transmembrane nucleoporin like 2" Q96KW2 6 27285903-27312273 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 71 "testis: 7.0" "Group enriched" "Detected in some" 5 "Early primary spermatocytes: 8.4;Late primary spermatocytes: 21.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA046150 Uncertain NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 47: Leukemia - Hemostasis" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" "HPA046150: " POMC "ACTH, CLIP, LPH, MSH, NPP, POC" ENSG00000115138 Proopiomelanocortin P01189 2 25160853-25168903 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Endorphin, Hormone" "Cancer-related genes, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 636 "pituitary gland: 30726.6" "Cell type enriched" "Detected in many" 151 "Corticotrophs: 97131.2" "Cell type enhanced" "Detected in many" "endothelial cell: 21.9" "Cancer enriched" "Detected in many" 4 "Testicular Germ Cell Tumor (TCGA): 41.4" "Region enriched" "Detected in all" 9 "hypothalamus: 68.4" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 3.4;lung cancer: 2.6;lymphoma: 2.8" "Pituitary gland - Corticotropes, Skin - Inner root sheath cells" "Region enriched" "Detected in all" 7 "hypothalamus: 44.0" "Region enriched" "Detected in all" 5 "hypothalamus: 117.7" "CAB002762, HPA046135, HPA063644, CAB079881" Enhanced "Secreted to blood" Hormone NA NA 380000 "Cluster 13: Non-specific - Mitochondria" "Cluster 20: Pituitary gland - Hormone signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 14 "CAB002762: , CAB079881: , HPA046135: , HPA063644: " "unprognostic (1.07e-1)" "unprognostic (4.56e-2)" "unprognostic (1.18e-1)" "unprognostic (6.17e-2)" "unprognostic (3.70e-1)" "unprognostic (1.15e-1)" "unprognostic (4.95e-2)" "unprognostic (6.53e-2)" "unprognostic (6.19e-2)" "unprognostic (7.25e-3)" "unprognostic (5.77e-2)" "unprognostic (1.10e-1)" "unprognostic (1.51e-1)" "unprognostic (1.30e-3)" "unprognostic (7.50e-2)" "unprognostic (6.36e-3)" "unprognostic (1.55e-1)" "unprognostic (2.60e-3)" "unprognostic (1.93e-1)" POMGNT1 "FLJ20277, LGMD2O, MEB, MGAT1.2" ENSG00000085998 "Protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)" Q8WZA1 1 46188683-46220305 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Limb-girdle muscular dystrophy, Lissencephaly, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 141.7;Endometrial luminal cells: 258.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044518 Approved NA NA 5500000 "Cluster 25: Non-specific - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 27: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 39 "HPA044518: " "unprognostic (3.69e-1)" "unprognostic (8.14e-2)" "unprognostic (4.37e-2)" "unprognostic (1.19e-2)" "unprognostic (5.94e-2)" "unprognostic (1.13e-1)" "unprognostic (3.83e-1)" "unprognostic (1.20e-2)" "unprognostic (1.81e-1)" "unprognostic (8.47e-2)" "unprognostic (5.15e-3)" "unprognostic (7.83e-2)" "unprognostic (8.46e-3)" "potential prognostic unfavorable (2.44e-4)" "unprognostic (2.36e-3)" "unprognostic (1.37e-1)" "unprognostic (7.30e-2)" "unprognostic (1.24e-2)" "unprognostic (4.05e-1)" "unprognostic (1.48e-1)" "unprognostic (2.79e-2)" "unprognostic (6.03e-3)" "unprognostic (7.65e-2)" "unprognostic (2.79e-1)" "unprognostic (2.70e-1)" "unprognostic (2.48e-1)" "unprognostic (2.11e-1)" "unprognostic (6.93e-3)" "unprognostic (2.37e-1)" "unprognostic (3.96e-3)" "unprognostic (1.79e-1)" POMGNT2 "AGO61, C3orf39, FLJ14566, GTDC2" ENSG00000144647 "Protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)" Q8NAT1 3 43079229-43106085 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Limb-girdle muscular dystrophy, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 42.5;Late spermatids: 42.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034870, HPA040989" Uncertain "Intracellular and membrane" Enzyme NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 108: Fibroblasts - ECM organization" 37 "HPA034870: , HPA040989: " "unprognostic (3.94e-2)" "unprognostic (4.41e-2)" "unprognostic (1.05e-1)" "unprognostic (9.87e-2)" "unprognostic (1.27e-1)" "unprognostic (1.41e-1)" "unprognostic (2.22e-2)" "unprognostic (2.83e-1)" "unprognostic (1.51e-2)" "potential prognostic favorable (1.93e-5)" "unprognostic (1.55e-1)" "unprognostic (2.11e-2)" "potential prognostic unfavorable (8.67e-5)" "unprognostic (1.01e-1)" "unprognostic (1.10e-1)" "unprognostic (1.26e-1)" "unprognostic (5.67e-2)" "unprognostic (2.79e-1)" "unprognostic (1.31e-1)" "unprognostic (4.88e-2)" "unprognostic (3.54e-2)" "unprognostic (7.91e-2)" "unprognostic (1.66e-2)" "potential prognostic favorable (5.89e-4)" "unprognostic (5.25e-2)" "unprognostic (2.75e-1)" "unprognostic (1.54e-1)" "unprognostic (2.20e-1)" "unprognostic (2.35e-1)" POMK "FLJ23356, SgK196" ENSG00000185900 "Protein O-mannose kinase" Q9H5K3 8 43093498-43131180 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Transferase" "Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Limb-girdle muscular dystrophy, Lissencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013321 Uncertain NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 64: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 82: Dendritic cells - Antigen presentation" 62 "HPA013321: " "unprognostic (1.17e-2)" "unprognostic (7.52e-2)" "unprognostic (2.36e-1)" "unprognostic (1.85e-2)" "unprognostic (1.29e-2)" "unprognostic (4.02e-1)" "potential prognostic favorable (8.61e-4)" "unprognostic (5.89e-2)" "unprognostic (7.17e-3)" "potential prognostic unfavorable (2.75e-5)" "unprognostic (1.35e-3)" "potential prognostic unfavorable (2.43e-5)" "unprognostic (1.43e-3)" "unprognostic (1.11e-3)" "unprognostic (2.22e-2)" "unprognostic (1.77e-2)" "potential prognostic favorable (1.80e-5)" "unprognostic (4.98e-2)" "unprognostic (1.89e-3)" "unprognostic (1.45e-2)" "unprognostic (1.88e-1)" "unprognostic (1.88e-1)" "unprognostic (4.11e-2)" "unprognostic (2.59e-1)" "unprognostic (1.36e-1)" "unprognostic (9.54e-3)" "unprognostic (2.92e-1)" "unprognostic (1.83e-2)" "unprognostic (3.39e-1)" POMP "C13orf12, HSPC014, UMP1" ENSG00000132963 "Proteasome maturation protein" Q9Y244 13 28659065-28678959 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" Chaperone "Ichthyosis, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 1075.8;Esophageal suprabasal cells: 972.3;Extravillous trophoblasts: 1242.2;Gastric progenitor cells: 975.4;Late primary spermatocytes: 1551.0;Syncytiotrophoblasts: 1163.8" "Cell type enhanced" "Detected in all" "endothelial cell: 207.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026995 Approved Supported "Nuclear speckles" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 78 "Nuclear speckles" "HPA026995: " "unprognostic (1.29e-1)" "unprognostic (2.75e-2)" "unprognostic (3.94e-1)" "unprognostic (2.12e-1)" "unprognostic (7.26e-2)" "unprognostic (4.16e-1)" "unprognostic (1.09e-3)" "unprognostic (3.74e-2)" "potential prognostic unfavorable (1.97e-5)" "unprognostic (4.78e-2)" "unprognostic (1.89e-3)" "unprognostic (3.66e-1)" "unprognostic (3.86e-2)" "validated prognostic unfavorable (1.31e-6)" "validated prognostic unfavorable (8.15e-4)" "unprognostic (2.42e-3)" "unprognostic (1.49e-3)" "unprognostic (3.32e-1)" "unprognostic (4.16e-1)" "unprognostic (3.86e-1)" "potential prognostic unfavorable (1.77e-4)" "unprognostic (1.77e-2)" "unprognostic (4.95e-2)" "unprognostic (4.71e-1)" "unprognostic (3.40e-1)" "unprognostic (3.05e-2)" "unprognostic (1.46e-1)" "unprognostic (1.31e-2)" "unprognostic (5.27e-2)" "unprognostic (2.49e-2)" "unprognostic (3.00e-1)" POMT1 LGMD2K ENSG00000130714 "Protein O-mannosyltransferase 1" Q9Y6A1 9 131502789-131523806 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Limb-girdle muscular dystrophy, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 84.5;Late primary spermatocytes: 76.8;Myonuclei: 72.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065252 Uncertain "Golgi apparatus" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 29: Forebrain - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 35: Neurons - Synaptic function & neurogenesis" 3 "Golgi apparatus" "HPA065252: " "unprognostic (1.97e-1)" "unprognostic (1.79e-3)" "unprognostic (7.69e-2)" "unprognostic (4.55e-2)" "unprognostic (6.59e-2)" "unprognostic (6.91e-2)" "unprognostic (4.24e-1)" "potential prognostic favorable (1.53e-7)" "unprognostic (2.32e-1)" "unprognostic (2.48e-1)" "potential prognostic favorable (3.73e-8)" "unprognostic (7.45e-3)" "unprognostic (2.39e-3)" "unprognostic (5.90e-3)" "unprognostic (2.70e-1)" "unprognostic (1.13e-1)" "unprognostic (2.69e-2)" "unprognostic (1.04e-2)" "unprognostic (1.23e-3)" "unprognostic (1.49e-1)" "unprognostic (2.05e-2)" "potential prognostic favorable (2.15e-4)" "unprognostic (9.46e-3)" "unprognostic (2.95e-2)" "unprognostic (1.14e-1)" "unprognostic (3.58e-1)" "unprognostic (2.25e-1)" "unprognostic (7.11e-2)" "unprognostic (1.11e-1)" "unprognostic (1.79e-2)" "unprognostic (1.96e-1)" POMT2 LGMD2N ENSG00000009830 "Protein O-mannosyltransferase 2" Q9UKY4 14 77274956-77320883 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital muscular dystrophy, Dystroglycanopathy, Limb-girdle muscular dystrophy, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Sertoli cells: 115.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003663 Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 67: Testis - Mixed function" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 3 Nucleoplasm "Nucleoli, Cytosol" "HPA003663: " "unprognostic (6.02e-3)" "unprognostic (3.39e-1)" "unprognostic (8.91e-2)" "unprognostic (3.90e-1)" "unprognostic (1.93e-1)" "unprognostic (2.80e-2)" "unprognostic (2.10e-1)" "unprognostic (1.62e-2)" "unprognostic (1.38e-2)" "unprognostic (1.72e-1)" "unprognostic (1.10e-1)" "unprognostic (3.41e-1)" "unprognostic (5.57e-3)" "potential prognostic unfavorable (4.55e-4)" "unprognostic (7.62e-2)" "unprognostic (1.22e-1)" "unprognostic (8.39e-2)" "unprognostic (1.11e-2)" "unprognostic (1.52e-1)" "unprognostic (3.39e-1)" "unprognostic (1.31e-1)" "unprognostic (1.33e-3)" "unprognostic (4.96e-3)" "unprognostic (1.96e-1)" "unprognostic (4.66e-3)" "unprognostic (4.51e-3)" "unprognostic (2.16e-1)" "unprognostic (2.11e-1)" "unprognostic (3.30e-1)" "unprognostic (4.54e-2)" "unprognostic (3.81e-1)" POMZP3 "POM-ZP3, POM121" ENSG00000146707 "POM121 and ZP3 fusion" Q6PJE2 7 76609986-76627279 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 22.9;Late primary spermatocytes: 50.6;Late spermatids: 85.9;Oocytes: 82.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA049817, HPA071198" Uncertain Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 39: Non-specific - Transcription" "Cluster 98: Neurons - Neurotransmission & signaling" 4 "Nucleoplasm, Nuclear membrane" "HPA049817: , HPA071198: " "unprognostic (1.43e-2)" "unprognostic (2.92e-1)" "unprognostic (3.36e-1)" "unprognostic (2.29e-3)" "unprognostic (2.30e-1)" "unprognostic (5.34e-3)" "unprognostic (1.94e-1)" "unprognostic (1.99e-2)" "unprognostic (2.01e-1)" "unprognostic (3.03e-3)" "unprognostic (1.48e-1)" "unprognostic (1.03e-1)" "unprognostic (1.66e-1)" "unprognostic (1.84e-3)" "unprognostic (3.09e-2)" "unprognostic (1.48e-1)" "unprognostic (1.61e-1)" "unprognostic (3.56e-1)" "unprognostic (3.04e-1)" "unprognostic (4.30e-3)" "unprognostic (4.07e-2)" "unprognostic (2.25e-1)" "unprognostic (1.20e-1)" "unprognostic (2.26e-1)" "unprognostic (1.82e-2)" "unprognostic (1.43e-2)" "unprognostic (1.33e-1)" "unprognostic (1.95e-1)" "unprognostic (2.45e-1)" "unprognostic (3.19e-1)" "unprognostic (2.66e-1)" PON1 "ESA, PON" ENSG00000005421 "Paraoxonase 1" P27169 7 95297676-95324532 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" Hydrolase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 104 "liver: 498.0" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 582.2" "Group enriched" "Detected in some" 11 "astrocyte: 15.4;Bergmann glia: 13.8;oligodendrocyte precursor cell: 7.5" "Cancer enriched" "Detected in some" 67 "Liver Hepatocellular Carcinoma (TCGA): 75.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 1.0;prostate cancer: 2.4" "Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA001610 Approved "Secreted to blood" Enzyme NA NA 96000000000 15000000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 59: Leukemia - T-cell receptor" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 4 "HPA001610: " "unprognostic (2.19e-1)" "validated prognostic favorable (3.99e-6)" "validated prognostic favorable (7.42e-4)" "unprognostic (2.94e-1)" "unprognostic (4.82e-2)" "unprognostic (9.97e-2)" "unprognostic (2.50e-2)" "unprognostic (2.44e-1)" PON2 ENSG00000105854 "Paraoxonase 2" Q15165 7 95404862-95435329 "Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 229.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 318.9;Astrocytes: 458.1;Bergmann glia: 476.2;Extravillous trophoblasts: 467.6;Myosatellite cells: 351.9" "Cell type enhanced" "Detected in many" "astrocyte: 456.4;Bergmann glia: 513.7;endothelial cell: 398.8" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 386.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 33.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025430, HPA029193" Enhanced "Secreted to blood" Enzyme NA NA 100000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 36: Brain & Liver - Signaling" "Cluster 39: Astrocytes - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 28: Astrocytes - Homeostasis & neuron support" 11 "CAB025430: , HPA029193: " "unprognostic (7.72e-2)" "unprognostic (1.53e-1)" "unprognostic (8.27e-2)" "unprognostic (3.25e-3)" "unprognostic (2.91e-1)" "unprognostic (1.32e-1)" "unprognostic (6.47e-2)" "unprognostic (2.04e-3)" "unprognostic (1.18e-2)" "unprognostic (1.95e-3)" "validated prognostic unfavorable (9.48e-4)" "validated prognostic unfavorable (1.36e-4)" "unprognostic (3.52e-3)" "unprognostic (1.82e-3)" "unprognostic (2.40e-2)" "unprognostic (3.32e-2)" "unprognostic (3.53e-1)" "potential prognostic unfavorable (9.13e-4)" "unprognostic (2.11e-2)" "unprognostic (7.17e-2)" "unprognostic (4.76e-2)" "unprognostic (9.29e-3)" "unprognostic (1.17e-3)" "unprognostic (2.96e-1)" "unprognostic (1.13e-1)" "unprognostic (2.21e-1)" "unprognostic (1.75e-1)" "unprognostic (4.61e-1)" "unprognostic (2.11e-1)" "unprognostic (5.91e-2)" "unprognostic (5.87e-1)" PON3 ENSG00000105852 "Paraoxonase 3" Q15166 7 95359872-95396375 "Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 20 "liver: 576.2" "Cell type enriched" "Detected in many" 9 "Hepatocytes: 660.4" "Group enriched" "Detected in some" 4 "astrocyte: 46.1;Bergmann glia: 33.3;fibroblast: 51.7;oligodendrocyte precursor cell: 33.1;pericyte: 32.7" "Group enriched" "Detected in many" 7 "Liver Hepatocellular Carcinoma (TCGA): 123.9;Lung Adenocarcinoma (TCGA): 53.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 14.6" "Liver - Hepatocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Gonadotropes, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA014848, CAB025250" Enhanced "Secreted to blood" Enzyme NA NA 1760000000 530000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 7: Liver cancer - Metabolism" "Cluster 93: Hepatocytes - Bile production & excretion" 1 "CAB025250: , HPA014848: " "unprognostic (8.63e-2)" "unprognostic (1.59e-1)" "unprognostic (9.69e-2)" "unprognostic (3.21e-2)" "unprognostic (1.57e-1)" "unprognostic (1.99e-2)" "unprognostic (2.81e-2)" "unprognostic (9.28e-2)" "potential prognostic unfavorable (5.57e-4)" "unprognostic (3.98e-3)" "validated prognostic favorable (6.23e-4)" "validated prognostic favorable (6.45e-4)" "unprognostic (1.02e-1)" "unprognostic (3.60e-1)" "unprognostic (4.97e-2)" "unprognostic (1.17e-2)" "unprognostic (1.79e-2)" "unprognostic (5.33e-2)" "unprognostic (9.98e-2)" "potential prognostic unfavorable (2.99e-4)" "unprognostic (2.01e-1)" "unprognostic (1.47e-2)" "unprognostic (1.22e-1)" "unprognostic (2.28e-1)" "unprognostic (1.42e-1)" POP1 ENSG00000104356 "POP1 homolog, ribonuclease P/MRP subunit" Q99575 8 98117293-98159835 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "tRNA processing" RNA-binding "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066194 Supported Nucleoli NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 100 Nucleoli "HPA066194: " "unprognostic (1.49e-1)" "unprognostic (1.20e-3)" "unprognostic (1.47e-2)" "unprognostic (8.13e-3)" "unprognostic (5.64e-2)" "unprognostic (1.34e-1)" "unprognostic (1.34e-1)" "potential prognostic favorable (1.39e-4)" "unprognostic (8.98e-2)" "potential prognostic unfavorable (1.09e-4)" "unprognostic (2.31e-3)" "unprognostic (8.20e-2)" "unprognostic (5.79e-2)" "potential prognostic unfavorable (1.17e-5)" "unprognostic (6.95e-3)" "unprognostic (4.16e-3)" "potential prognostic unfavorable (8.16e-4)" "unprognostic (4.91e-2)" "unprognostic (2.46e-2)" "unprognostic (1.88e-1)" "unprognostic (2.55e-1)" "unprognostic (8.32e-2)" "unprognostic (1.52e-3)" "unprognostic (2.30e-3)" "unprognostic (6.49e-3)" "unprognostic (2.86e-1)" "unprognostic (4.18e-2)" "unprognostic (5.53e-2)" "unprognostic (1.11e-1)" "unprognostic (1.48e-1)" "unprognostic (1.15e-1)" POP4 RPP29 ENSG00000105171 "POP4 homolog, ribonuclease P/MRP subunit" O95707 19 29606283-29617237 "Essential proteins, Predicted intracellular proteins" "tRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric progenitor cells: 147.4;Late primary spermatocytes: 121.8;Oocytes: 96.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042748, HPA064577" Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 39 "Nucleoplasm, Nucleoli" "HPA042748: , HPA064577: " "unprognostic (1.02e-1)" "unprognostic (1.60e-1)" "unprognostic (2.24e-1)" "unprognostic (2.76e-3)" "unprognostic (8.69e-2)" "unprognostic (9.55e-2)" "unprognostic (3.82e-3)" "unprognostic (6.05e-2)" "unprognostic (1.60e-1)" "unprognostic (8.82e-2)" "potential prognostic favorable (2.07e-5)" "unprognostic (2.82e-1)" "unprognostic (6.85e-2)" "unprognostic (6.83e-2)" "unprognostic (5.43e-3)" "unprognostic (6.54e-2)" "unprognostic (5.79e-2)" "unprognostic (7.00e-2)" "unprognostic (9.61e-2)" "unprognostic (4.80e-2)" "unprognostic (1.38e-2)" "unprognostic (4.86e-3)" "unprognostic (1.35e-1)" "unprognostic (1.30e-2)" "unprognostic (3.17e-2)" "unprognostic (2.30e-1)" "unprognostic (1.98e-2)" "unprognostic (1.76e-1)" "unprognostic (1.43e-1)" "unprognostic (1.16e-1)" "unprognostic (2.95e-2)" POP5 ENSG00000167272 "POP5 homolog, ribonuclease P/MRP subunit" Q969H6 12 120578764-120581402 "Essential proteins, Predicted intracellular proteins" "rRNA processing, tRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047598, HPA069204" Approved Supported Nucleoplasm,Nucleoli NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 28: Liver & Adrenal gland - Secretion" "Cluster 21: Non-specific - Metabolism" "Cluster 38: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 36 Nucleoplasm Nucleoli "HPA047598: , HPA069204: " "unprognostic (2.75e-2)" "unprognostic (2.16e-1)" "unprognostic (2.22e-1)" "unprognostic (7.19e-3)" "unprognostic (4.34e-2)" "unprognostic (1.28e-1)" "unprognostic (2.95e-1)" "unprognostic (1.36e-2)" "unprognostic (6.47e-2)" "unprognostic (7.65e-3)" "unprognostic (4.15e-1)" "unprognostic (1.72e-2)" "unprognostic (2.32e-1)" "unprognostic (1.14e-2)" "unprognostic (2.08e-3)" "unprognostic (7.79e-3)" "unprognostic (2.06e-1)" "unprognostic (1.03e-1)" "unprognostic (4.25e-1)" "unprognostic (3.00e-2)" "unprognostic (1.82e-2)" "unprognostic (5.28e-2)" "unprognostic (3.03e-1)" "unprognostic (5.79e-2)" "unprognostic (2.30e-2)" "unprognostic (9.19e-2)" "unprognostic (2.95e-2)" "unprognostic (6.35e-2)" "unprognostic (1.63e-1)" "unprognostic (4.24e-1)" "unprognostic (2.20e-2)" POP7 "RPP2, RPP20" ENSG00000172336 "POP7 homolog, ribonuclease P/MRP subunit" O75817 7 100706121-100707486 "Essential proteins, Predicted intracellular proteins" "rRNA processing, tRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 169.1;Esophageal apical cells: 150.4;Esophageal basal cells: 135.8;Extravillous trophoblasts: 205.1;Gastric progenitor cells: 180.7;Migrating cytotrophoblasts: 188.8;Syncytiotrophoblasts: 153.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021007 Uncertain Supported Nucleoli,Vesicles NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 42 "Nucleoli, Vesicles" "HPA021007: " "unprognostic (4.84e-1)" "unprognostic (1.15e-1)" "unprognostic (2.72e-2)" "unprognostic (2.50e-1)" "unprognostic (7.31e-2)" "unprognostic (1.13e-2)" "potential prognostic unfavorable (5.81e-4)" "unprognostic (2.14e-1)" "unprognostic (2.78e-1)" "potential prognostic unfavorable (1.61e-4)" "potential prognostic unfavorable (1.10e-7)" "unprognostic (1.38e-2)" "unprognostic (1.31e-1)" "validated prognostic unfavorable (5.35e-7)" "validated prognostic unfavorable (3.02e-5)" "unprognostic (1.30e-2)" "unprognostic (6.25e-2)" "unprognostic (3.10e-2)" "unprognostic (8.61e-2)" "unprognostic (1.71e-1)" "unprognostic (5.72e-2)" "unprognostic (1.23e-1)" "unprognostic (4.24e-2)" "unprognostic (2.11e-1)" "unprognostic (2.52e-2)" "unprognostic (1.08e-1)" "unprognostic (1.85e-3)" "unprognostic (3.06e-2)" "unprognostic (2.47e-1)" "unprognostic (1.97e-1)" "unprognostic (2.78e-2)" POPDC2 POP2 ENSG00000121577 "Popeye domain containing 2" Q9HBU9 3 119636457-119665324 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "heart muscle: 378.0" "Group enriched" "Detected in many" 5 "Cardiomyocytes: 81.5;Myonuclei: 41.0;Smooth muscle cells: 88.2;Thymic myoid cells: 116.9" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 17.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 5 "Neuroblastoma: 4.5;testis cancer: 2.3" "Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Skin - Smooth muscle cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA024255 Enhanced NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 35: Non-specific - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 62: Smooth muscle cells - Muscle contraction" "HPA024255: " "unprognostic (6.61e-3)" "unprognostic (1.61e-1)" "unprognostic (2.04e-3)" "unprognostic (3.12e-3)" "unprognostic (3.77e-3)" "unprognostic (2.00e-1)" "unprognostic (1.17e-1)" "unprognostic (1.43e-1)" "unprognostic (1.63e-1)" "unprognostic (1.95e-2)" "validated prognostic favorable (7.22e-5)" "validated prognostic favorable (8.04e-6)" "unprognostic (1.05e-2)" "unprognostic (7.94e-2)" "unprognostic (3.26e-2)" "unprognostic (8.50e-2)" "unprognostic (7.73e-2)" "unprognostic (2.59e-2)" "unprognostic (1.75e-1)" "unprognostic (9.94e-3)" "unprognostic (1.08e-1)" "unprognostic (7.74e-2)" "unprognostic (3.27e-2)" "unprognostic (7.41e-3)" "unprognostic (7.41e-2)" "unprognostic (1.66e-1)" POPDC3 "bA355M14.1, MGC22671, POP3" ENSG00000132429 "Popeye domain containing 3" Q9HBV1 6 105157900-105180014 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "heart muscle: 19.4;skeletal muscle: 76.4;tongue: 27.6" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 82.1;Early spermatids: 140.2;Gastric chief cells: 20.7;Late spermatids: 22.8;Myonuclei: 98.3;Myosatellite cells: 33.5;Oocytes: 23.0;Pancreatic islet cells: 22.9;Retinal pigment epithelial cells: 29.8" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 3.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Pancreas - Alpha cells, Prostate - Smooth muscle cells, Stomach - Chief cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA012514 Approved Nucleoli,Cytosol NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 30: White matter - Myelination" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 1 "Nucleoli, Cytosol" "HPA012514: " "unprognostic (2.77e-3)" "unprognostic (6.71e-2)" "unprognostic (4.41e-2)" "unprognostic (3.50e-1)" "unprognostic (3.29e-3)" "unprognostic (1.37e-1)" "unprognostic (2.16e-2)" "potential prognostic unfavorable (2.81e-4)" "unprognostic (1.02e-2)" "unprognostic (2.32e-3)" "unprognostic (6.94e-2)" "unprognostic (2.95e-1)" "unprognostic (1.03e-2)" POR "CYPOR, FLJ26468" ENSG00000127948 "Cytochrome p450 oxidoreductase" P16435 7 75899200-75986855 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Congenital adrenal hyperplasia, Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 292.8" "Cell type enhanced" "Detected in many" "Enterocytes: 377.8;Hepatocytes: 709.7;Neutrophils: 512.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Kidney - Macrophages, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004372, HPA010136, HPA014181" Enhanced Supported Nucleoplasm,Vesicles,Cytosol NA NA 25000 "Cluster 35: Neutrophils - Protein binding" "Cluster 76: Non-specific - Metabolism" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 39: Non-specific - Transcription" "Cluster 93: Hepatocytes - Bile production & excretion" 54 Vesicles "Nucleoplasm, Cytosol" "CAB004372: , HPA010136: , HPA014181: " "unprognostic (5.55e-2)" "unprognostic (7.66e-2)" "unprognostic (2.05e-1)" "unprognostic (4.38e-2)" "unprognostic (1.66e-1)" "unprognostic (7.97e-2)" "unprognostic (3.86e-2)" "unprognostic (2.93e-2)" "unprognostic (4.40e-2)" "unprognostic (6.86e-2)" "potential prognostic favorable (3.95e-6)" "unprognostic (1.96e-1)" "unprognostic (2.61e-1)" "unprognostic (2.66e-2)" "unprognostic (3.87e-3)" "unprognostic (3.38e-2)" "unprognostic (3.29e-2)" "unprognostic (6.47e-2)" "unprognostic (2.28e-2)" "unprognostic (9.79e-2)" "unprognostic (4.66e-3)" "unprognostic (3.09e-1)" "unprognostic (6.92e-2)" "unprognostic (5.48e-2)" "unprognostic (3.25e-1)" "unprognostic (3.75e-1)" "unprognostic (7.46e-2)" "unprognostic (4.75e-2)" "unprognostic (5.20e-1)" "potential prognostic unfavorable (7.54e-4)" "unprognostic (3.05e-1)" PORCN "DHOF, MG61, por, PORC, PPN" ENSG00000102312 "Porcupine O-acyltransferase" Q9H237 X 48508959-48520814 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Wnt signaling pathway" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 30.9" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 42.8;Endometrial secretory cells: 26.3;Esophageal apical cells: 99.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049215, HPA058413" Enhanced Approved Vesicles NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 51: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" Vesicles "HPA049215: , HPA058413: " "unprognostic (9.66e-2)" "unprognostic (2.31e-2)" "unprognostic (2.07e-1)" "unprognostic (6.53e-2)" "unprognostic (2.24e-1)" "unprognostic (2.01e-2)" "unprognostic (2.33e-1)" "unprognostic (2.64e-2)" "unprognostic (3.69e-1)" "unprognostic (2.50e-1)" "unprognostic (2.60e-2)" "unprognostic (3.26e-2)" "unprognostic (1.68e-1)" "potential prognostic unfavorable (3.08e-5)" "unprognostic (5.97e-2)" "unprognostic (2.72e-1)" "unprognostic (1.09e-1)" "unprognostic (1.15e-1)" "unprognostic (4.70e-2)" "unprognostic (8.98e-2)" "unprognostic (1.86e-2)" "unprognostic (2.71e-1)" "unprognostic (6.99e-2)" "unprognostic (6.05e-2)" "unprognostic (3.45e-1)" "unprognostic (9.33e-2)" "unprognostic (1.59e-2)" "unprognostic (2.01e-1)" "unprognostic (9.06e-2)" "unprognostic (7.00e-2)" "unprognostic (5.78e-2)" POSTN "OSF-2, periostin, PN" ENSG00000133110 Periostin Q15063 13 37562583-37598844 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 195.7;stomach 1: 165.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 226.5;Breast myoepithelial cells: 424.5;Fibroblasts: 246.1;Medullary thymic epithelial cells: 412.8;Pericytes: 90.2;Respiratory ionocytes: 734.1;Smooth muscle cells: 129.0;Vascular endothelial cells: 400.1" "Cell type enhanced" "Detected in many" "amygdala excitatory: 85.3;hippocampal CA1-3: 107.8;hippocampal dentate gyrus: 109.7;miscellaneous: 74.7" "Cancer enhanced" "Detected in all" "Breast Invasive Carcinoma (TCGA): 616.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "breast cancer: 132.1;Rhabdoid: 411.9;testis cancer: 405.9" "Minor Salivary Gland - Macrophages, Testis - Endothelial cells" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 6 "spinal cord: 120.5" "HPA012306, HPA071023" Enhanced Approved "Golgi apparatus" "Secreted to extracellular matrix" "Cell adhesion" NA NA 300000000 "Cluster 58: Skin - Keratinization" "Cluster 51: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 1 "Golgi apparatus" "HPA012306: , HPA071023: " "unprognostic (5.18e-3)" "unprognostic (2.78e-2)" "unprognostic (3.30e-2)" "potential prognostic unfavorable (8.97e-4)" "unprognostic (1.50e-2)" "unprognostic (1.79e-1)" "unprognostic (4.09e-2)" "potential prognostic unfavorable (1.17e-4)" "unprognostic (1.75e-2)" "unprognostic (1.56e-2)" "unprognostic (2.11e-2)" "unprognostic (5.45e-2)" "unprognostic (1.02e-2)" "unprognostic (6.34e-3)" "unprognostic (3.00e-1)" "unprognostic (3.38e-3)" "potential prognostic unfavorable (8.86e-4)" "unprognostic (1.51e-2)" "unprognostic (3.42e-2)" "unprognostic (8.78e-3)" "potential prognostic unfavorable (4.05e-6)" "unprognostic (3.77e-2)" "unprognostic (1.10e-1)" "unprognostic (2.01e-1)" "unprognostic (6.35e-2)" "unprognostic (2.05e-2)" "unprognostic (9.99e-3)" "potential prognostic unfavorable (2.56e-4)" "unprognostic (9.94e-2)" "unprognostic (4.02e-2)" "unprognostic (7.80e-2)" POT1 "DKFZp586D211, hPot1" ENSG00000128513 "Protection of telomeres 1" Q9NUX5 7 124822386-124929983 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" DNA-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 168.4;Lactotrophs: 122.1;Sertoli cells: 140.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068538 Supported Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 39: Non-specific - Transcription" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 60 Nucleoplasm "HPA068538: " "unprognostic (1.04e-1)" "unprognostic (1.44e-1)" "unprognostic (1.73e-2)" "unprognostic (3.51e-2)" "unprognostic (1.60e-1)" "unprognostic (1.12e-1)" "unprognostic (9.57e-2)" "unprognostic (5.57e-2)" "unprognostic (4.77e-1)" "unprognostic (3.99e-3)" "potential prognostic favorable (1.73e-4)" "unprognostic (1.13e-1)" "unprognostic (6.27e-2)" "unprognostic (2.01e-3)" "unprognostic (1.40e-2)" "unprognostic (6.63e-2)" "unprognostic (3.60e-2)" "unprognostic (4.60e-1)" "unprognostic (3.57e-2)" "unprognostic (7.90e-2)" "unprognostic (2.19e-1)" "unprognostic (9.82e-3)" "unprognostic (3.76e-2)" "unprognostic (2.41e-1)" "unprognostic (4.82e-3)" "unprognostic (1.01e-1)" "unprognostic (1.60e-1)" "unprognostic (5.05e-2)" "unprognostic (1.21e-1)" "unprognostic (3.24e-2)" "unprognostic (6.07e-2)" POTEA "A26A1, CT104.3, POTE-8, POTE8" ENSG00000188877 "POTE ankyrin domain family member A" 8 43292483-43363518 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 11 "testis: 1.1" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 2.0;Early primary spermatocytes: 3.6;Gastric chief cells: 1.1;Late primary spermatocytes: 2.3;Parietal cells: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 20: Myeloma - Immune response" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" POTEB "A26B1, CT104.5, POTE-15, POTE15" ENSG00000233917 "POTE ankyrin domain family member B" A0A0A6YYL3 15 21846329-21877735 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 12 "testis: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 23: Testis - Spermatogenesis" POTEB2 ENSG00000230031 "POTE ankyrin domain family member B2" H3BUK9 15 20835372-20866314 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 12 "testis: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 6: Testis - Spermatogenesis" POTEB3 ENSG00000278522 "POTE ankyrin domain family member B3" A0JP26 15 21405401-21440499 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 19 "testis: 4.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 9: Non-specific - Receptor signaling" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 3: Early primary spermatocytes - Early meiosis" 7 "unprognostic (8.85e-2)" "unprognostic (1.43e-1)" POTEC "A26B2, CT104.6, DKFZp686J0529, POTE-18, POTE18" ENSG00000183206 "POTE ankyrin domain family member C" B2RU33 18 14507339-14543600 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 18 "testis: 1.8" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 4.4;Early primary spermatocytes: 24.1;Epicardial cells: 2.3;Late primary spermatocytes: 15.2;Late spermatids: 1.9;Undifferentiated spermatogonia: 7.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" "unprognostic (5.22e-1)" POTED "A26B3, ANKRD21, CT104.1, POTE, POTE-21, POTE21" ENSG00000166351 "POTE ankyrin domain family member D" Q86YR6 21 13609777-13645823 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 11 "testis: 2.8" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 1.2;Early primary spermatocytes: 2.9;Late primary spermatocytes: 1.5;Undifferentiated spermatogonia: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" NA NA "Cluster 47: Testis - Mixed function" "Cluster 24: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" POTEE "A26C1, A26C1A, CT104.2, POTE-2, POTE2, POTE2gamma" ENSG00000188219 "POTE ankyrin domain family member E" Q6S8J3 2 131209536-131265278 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Ependymal cells: 22.6;Prostatic glandular cells: 18.3" "Cell type enriched" "Detected in single" 42 "ependymal cell: 19.6" "Not detected" "Not detected" "Region enhanced" "Detected in some" "spinal cord: 4.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 4.0" "Prostate - Prostate glandular cells, Skeletal muscle - Skeletal myocytes" "HPA041264, HPA041271, HPA043260" Uncertain NA NA "Cluster 46: Brainstem - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 34: Ciliated cells - Cilia assembly & function" 17 "HPA041264: , HPA041271: , HPA043260: " "unprognostic (1.52e-1)" POTEF "A26C1B, POTE2alpha, POTEACTIN" ENSG00000196604 "POTE ankyrin domain family member F" A5A3E0 2 130073535-130129222 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "testis: 1.7" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 7.1;Differentiating spermatogonia: 16.5;Early primary spermatocytes: 11.8;Lactotrophs: 12.8;Late primary spermatocytes: 6.8;Migrating cytotrophoblasts: 3.9;Prostatic glandular cells: 7.2;Undifferentiated spermatogonia: 62.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skeletal muscle - Skeletal myocytes" "HPA041264, HPA041271, HPA043260" Uncertain NA NA 1300000000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 79: Testis - Spermatogenesis" "Cluster 46: Brainstem - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 57 "HPA041264: , HPA041271: , HPA043260: " "unprognostic (3.65e-2)" "unprognostic (2.03e-1)" "potential prognostic unfavorable (7.16e-4)" "unprognostic (4.38e-1)" POTEG "A26C2, CT104.4, POTE-14, POTE14, POTE14alpha" ENSG00000187537 "POTE ankyrin domain family member G" Q6S5H5 14 19402486-19434341 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 4 "Prostatic glandular cells: 48.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Prostate - Prostate glandular cells" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" POTEH "A26C3, ACTBL1, CT104.7, POTE22" ENSG00000198062 "POTE ankyrin domain family member H" Q6S545 22 15690026-15721631 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "prostate: 1.5" "Cell type enriched" "Detected in some" 8 "Prostatic glandular cells: 61.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Prostate - Prostate glandular cells" NA NA "Cluster 21: Testis - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" POTEI POTE2beta ENSG00000196834 "POTE ankyrin domain family member I" P0CG38 2 130459455-130509707 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 7 "prostate: 2.4;testis: 3.1" "Group enriched" "Detected in some" 4 "Prostatic glandular cells: 8.5;Tuft cells: 11.5" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Breast Invasive Carcinoma (TCGA): 1.9;Prostate Adenocarcinoma (TCGA): 3.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Breast - Breast glandular cells, Prostate - Prostate glandular cells, Testis - Early spermatids" "HPA041264, HPA041271, HPA043260" Uncertain NA NA 810000000 "Cluster 21: Testis - Mixed function" "Cluster 46: Brainstem - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 16 "HPA041264: , HPA041271: , HPA043260: " "unprognostic (5.39e-2)" "unprognostic (1.10e-1)" "potential prognostic unfavorable (9.00e-4)" "unprognostic (2.37e-1)" "unprognostic (3.95e-2)" POTEJ POTE2beta ENSG00000222038 "POTE ankyrin domain family member J" P0CG39 2 130611440-130658037 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 8 "Prostatic glandular cells: 30.4" "Not detected" "Not detected" "Region enhanced" "Detected in single" "hypothalamus: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skeletal muscle - Skeletal myocytes" "HPA041264, HPA041271, HPA043260" Uncertain NA NA "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 61: BICR 18 - Protein kinases" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 5 "HPA041264: , HPA041271: , HPA043260: " POTEM "ACT, P704P, POTE14beta" ENSG00000222036 "POTE ankyrin domain family member M" A6NI47 14 18967434-19003752 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 14 "prostate: 17.6;testis: 5.4" "Cell type enriched" "Detected in some" 26 "Prostatic glandular cells: 96.4" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 16 "Prostate Adenocarcinoma (TCGA): 13.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Prostate glandular cells" NA NA "Cluster 21: Testis - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" "unprognostic (1.61e-2)" "unprognostic (1.14e-1)" "unprognostic (4.46e-1)" POU1F1 "GHF-1, PIT-1, PIT1, POU1F1a" ENSG00000064835 "POU class 1 homeobox 1" P28069 3 87259404-87276584 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 135 "pituitary gland: 55.4" "Group enriched" "Detected in some" 62 "Lactotrophs: 376.7;Somatotrophs: 202.6;Thyrotrophs: 279.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Bone cancer: 1.1" "Pituitary gland - Lactotropes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA041646, HPA050624" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 20: Pituitary gland - Hormone signaling" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 14 "Nucleoplasm, Cytosol" "HPA041646: , HPA050624: " POU2AF1 "BOB1, OBF1, OCA-B" ENSG00000110777 "POU class 2 homeobox associating factor 1" Q16633 11 111352255-111455630 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 41.3;lymphoid tissue: 111.9;stomach 1: 37.8" "Cell type enhanced" "Detected in many" "B-cells: 157.5;Choroid plexus epithelial cells: 376.7;Endometrial ciliated cells: 79.7;Ependymal cells: 101.9;Gastric chief cells: 105.9;Mucous neck cells: 84.7;Plasma cells: 538.2;Respiratory ciliated cells: 183.4" "Group enriched" "Detected in some" 5 "choroid plexus epithelial cell: 244.6;ependymal cell: 112.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "memory B-cell: 33.6;naive B-cell: 24.1" "Lineage enriched" "Detected in many" 8 "B-cells: 33.6" "Group enriched" "Detected in many" 7 "lymphoma: 239.1;Myeloma: 242.2" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pituitary gland - Plasma cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB011193 Enhanced NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 8: Immune cells - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 44: Plasma cells - Antibody production & secretion" 39 "CAB011193: " "unprognostic (7.49e-3)" "potential prognostic favorable (1.93e-5)" "unprognostic (3.19e-1)" "unprognostic (4.16e-2)" "unprognostic (2.00e-2)" "unprognostic (3.22e-1)" "unprognostic (4.77e-3)" "unprognostic (3.06e-3)" "potential prognostic unfavorable (2.50e-4)" "unprognostic (1.96e-1)" "unprognostic (3.72e-3)" "unprognostic (6.49e-2)" "unprognostic (2.13e-1)" "unprognostic (3.13e-3)" "unprognostic (6.55e-3)" "unprognostic (1.62e-1)" "unprognostic (1.93e-1)" "unprognostic (9.63e-3)" "unprognostic (3.69e-2)" "unprognostic (5.15e-2)" "unprognostic (3.64e-1)" "unprognostic (4.66e-2)" "unprognostic (5.09e-2)" "unprognostic (8.55e-2)" "unprognostic (1.21e-1)" "unprognostic (2.73e-1)" "unprognostic (2.46e-1)" "unprognostic (3.01e-2)" "unprognostic (1.96e-1)" POU2AF2 "C11orf53, MGC50104, OCA-T1" ENSG00000150750 "POU class 2 homeobox associating factor 2" Q8IXP5 11 111245725-111286401 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "stomach 1: 2.9;testis: 4.9" "Group enriched" "Detected in some" 10 "Late primary spermatocytes: 60.2;Tuft cells: 219.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 11.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 5.0" "Lung - Respiratory ciliated cells, Pancreas - Ductal cells, Stomach - Chief cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA056128, HPA073101" Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 21: Testis - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 95: Tuft cells - Chemosensory signaling" Nucleoplasm Vesicles "HPA056128: , HPA073101: " "unprognostic (2.91e-2)" "unprognostic (2.36e-1)" "unprognostic (2.00e-2)" "unprognostic (1.93e-1)" "unprognostic (7.53e-2)" "unprognostic (1.21e-1)" "unprognostic (3.03e-3)" "unprognostic (2.63e-1)" "unprognostic (7.90e-3)" "unprognostic (2.20e-2)" "unprognostic (1.65e-1)" "unprognostic (2.22e-2)" "unprognostic (4.11e-2)" "unprognostic (2.76e-1)" POU2AF3 "C11orf93, CASC13, COLCA2, OCA-T2" ENSG00000214290 "POU class 2 homeobox associating factor 3" A8K830 11 111298546-111308735 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 29.5;Cholangiocytes: 31.0;Early spermatids: 111.8;Fallopian tube ciliated cells: 31.5;Late spermatids: 94.9;Respiratory ciliated cells: 38.7" "Cell type enhanced" "Detected in many" "astrocyte: 22.4;ependymal cell: 28.1" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 46.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 25.3;prostate cancer: 34.2" "Lung - Respiratory ciliated cells, Skeletal muscle - Fibroblasts, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040625 Supported Nucleoplasm,Cytosol NA NA "Cluster 38: Non-specific - Basic cellular processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 24: Non-specific - Unknown function" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" Nucleoplasm Cytosol "HPA040625: " "unprognostic (3.47e-1)" "unprognostic (4.67e-3)" "unprognostic (4.35e-1)" "potential prognostic unfavorable (3.58e-4)" "unprognostic (2.12e-1)" "unprognostic (6.95e-2)" "unprognostic (6.03e-2)" "unprognostic (7.99e-2)" "unprognostic (1.88e-1)" "unprognostic (3.41e-3)" "unprognostic (1.20e-1)" "potential prognostic favorable (7.40e-4)" "unprognostic (1.43e-3)" "unprognostic (1.65e-3)" "unprognostic (7.68e-2)" "unprognostic (8.83e-3)" "unprognostic (3.01e-1)" "unprognostic (1.61e-1)" "unprognostic (2.87e-3)" "unprognostic (6.43e-3)" "unprognostic (1.29e-2)" "unprognostic (1.35e-1)" "unprognostic (8.16e-2)" "unprognostic (8.77e-3)" "unprognostic (8.03e-3)" "unprognostic (1.51e-1)" "unprognostic (5.16e-2)" "unprognostic (3.55e-2)" POU2F1 "OCT1, OTF1" ENSG00000143190 "POU class 2 homeobox 1" P14859 1 167220876-167427345 "Essential proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 4.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002608, HPA028256, HPA058559, HPA064323" Supported Approved "Nucleoplasm,Endoplasmic reticulum,Vesicles" No No "Cluster 2: Dendritic cells - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 15: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 39 Nucleoplasm "Endoplasmic reticulum, Vesicles" "CAB002608: , HPA028256: , HPA058559: , HPA064323: " "unprognostic (9.40e-2)" "unprognostic (7.87e-3)" "unprognostic (1.28e-1)" "unprognostic (1.48e-2)" "unprognostic (4.09e-2)" "unprognostic (9.02e-3)" "unprognostic (4.08e-2)" "unprognostic (1.58e-2)" "unprognostic (2.59e-2)" "unprognostic (6.31e-2)" "unprognostic (1.69e-3)" "unprognostic (4.46e-3)" "unprognostic (3.39e-2)" "potential prognostic unfavorable (5.26e-4)" "unprognostic (5.06e-2)" "unprognostic (3.47e-2)" "unprognostic (8.00e-2)" "unprognostic (6.45e-2)" "unprognostic (1.32e-2)" "unprognostic (3.00e-1)" "unprognostic (2.22e-1)" "unprognostic (8.00e-3)" "unprognostic (8.22e-3)" "unprognostic (2.01e-1)" "unprognostic (8.44e-2)" "unprognostic (1.56e-1)" "unprognostic (4.51e-1)" "unprognostic (1.19e-1)" "unprognostic (1.83e-1)" "unprognostic (1.41e-2)" "unprognostic (2.60e-2)" POU2F2 "OCT2, OTF2" ENSG00000028277 "POU class 2 homeobox 2" P09086 19 42086110-42196585 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 47.4" "Cell type enhanced" "Detected in many" "B-cells: 340.8;cDC: 168.4;Early primary spermatocytes: 156.4;Kupffer cells: 108.6;Macrophages: 119.6;Microglia: 129.5;Monocyte progenitors: 118.5;monocytes: 259.0;Neutrophils: 165.8;Plasma cells: 145.3;Retinal bipolar cells: 104.2" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 157.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 95.1" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 4 "lymphoma: 105.5;Myeloma: 32.3" "Liver - Kupffer cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002513, HPA049056, HPA062096, HPA064404, HPA073998" Enhanced Enhanced Nucleoplasm,Vesicles NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 55: Lymphoma - Immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 10 "Nucleoplasm, Vesicles" "CAB002513: , HPA049056: , HPA062096: , HPA064404: , HPA073998: " "unprognostic (1.04e-2)" "unprognostic (2.14e-2)" "unprognostic (1.37e-2)" "unprognostic (1.04e-1)" "unprognostic (3.07e-2)" "unprognostic (3.40e-1)" "unprognostic (1.86e-2)" "unprognostic (3.52e-2)" "unprognostic (9.15e-2)" "unprognostic (9.70e-2)" "unprognostic (3.41e-3)" "unprognostic (3.45e-2)" "unprognostic (1.13e-1)" "unprognostic (2.63e-2)" "unprognostic (3.65e-1)" "unprognostic (2.24e-2)" "unprognostic (9.99e-2)" "unprognostic (1.76e-1)" "unprognostic (3.67e-2)" "unprognostic (3.42e-1)" "unprognostic (1.02e-3)" "unprognostic (1.67e-1)" "unprognostic (1.46e-1)" "unprognostic (8.78e-3)" "unprognostic (7.01e-2)" "unprognostic (3.85e-1)" "unprognostic (8.54e-2)" "unprognostic (1.28e-1)" "unprognostic (2.72e-2)" POU2F3 "Epoc-1, OCT11, PLA-1, Skn-1a" ENSG00000137709 "POU class 2 homeobox 3" Q9UKI9 11 120236640-120319945 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skin 1: 44.9" "Cell type enriched" "Detected in many" 11 "Tuft cells: 737.8" "Cell type enhanced" "Detected in some" "deep-layer near-projecting: 2.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 5.3" "Lung - Alveolar cells type 2, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA019652, HPA073468" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 37: Skin - Keratinization" "Cluster 48: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 95: Tuft cells - Chemosensory signaling" 1 Nucleoplasm "Plasma membrane, Cytosol" "HPA019652: , HPA073468: " "unprognostic (3.60e-2)" "unprognostic (7.29e-2)" "unprognostic (8.53e-2)" "potential prognostic favorable (2.48e-5)" "unprognostic (3.16e-1)" "unprognostic (6.93e-3)" "unprognostic (6.21e-2)" "unprognostic (5.39e-2)" "unprognostic (7.83e-2)" "unprognostic (3.32e-1)" "unprognostic (7.56e-2)" "unprognostic (1.49e-3)" "unprognostic (6.06e-2)" "unprognostic (3.20e-2)" "unprognostic (2.46e-2)" "unprognostic (6.62e-3)" "unprognostic (5.32e-3)" POU3F1 "OCT6, OTF6, SCIP" ENSG00000185668 "POU class 3 homeobox 1" Q03052 1 38043829-38046793 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 8.7;skin 1: 30.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 25.4;Bergmann glia: 31.6;Breast lactating cells: 24.0;Breast myoepithelial cells: 105.1;Epididymal basal cells: 84.3;Schwann cells: 50.9;Suprabasal keratinocytes: 33.8;Urothelial cells: 22.5" "Cell type enhanced" "Detected in many" "Bergmann glia: 35.7;hippocampal CA1-3: 47.1;miscellaneous: 31.3" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 5.9;Skin Cutaneous Melanoma (TCGA): 6.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Bone cancer: 19.8" "Skin - Keratinocyte (other), Testis - Spermatogonia" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "hippocampal formation: 9.9" "HPA055980, HPA073824" Enhanced Nucleoplasm NA NA "Cluster 37: Skin - Keratinization" "Cluster 51: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 20: Non-specific - Transcription regulation" Nucleoplasm "HPA055980: , HPA073824: " "unprognostic (1.19e-1)" "unprognostic (1.98e-1)" "unprognostic (1.44e-2)" "unprognostic (2.17e-2)" "unprognostic (2.88e-2)" "unprognostic (1.60e-2)" "unprognostic (2.05e-1)" "unprognostic (1.35e-1)" "unprognostic (1.64e-1)" POU3F2 "BRN2, OCT7, OTF7, POUF3" ENSG00000184486 "POU class 3 homeobox 2" P20265 6 98834574-98839458 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 21 "brain: 11.1" "Cell type enhanced" "Detected in some" "Astrocytes: 96.1;Bergmann glia: 61.1;Ependymal cells: 44.9;Müller glia: 12.6;Oligodendrocyte progenitor cells: 48.0;Oligodendrocytes: 17.4;Other brain neurons: 18.9" "Cell type enhanced" "Detected in many" "astrocyte: 119.2;Bergmann glia: 66.7;ependymal cell: 64.8" "Cancer enriched" "Detected in some" 10 "Glioblastoma Multiforme (TCGA): 27.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 28.3;skin cancer: 12.5" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047081, HPA056261" Approved Supported Nucleoplasm NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 28: Astrocytes - Homeostasis & neuron support" 10 Nucleoplasm "HPA047081: , HPA056261: " "unprognostic (3.75e-1)" "unprognostic (1.20e-1)" "unprognostic (3.05e-1)" "unprognostic (1.33e-2)" "unprognostic (6.85e-2)" POU3F3 "BRN1, OTF8" ENSG00000198914 "POU class 3 homeobox 3" P20264 2 104853287-104858574 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 17 "brain: 29.8;epididymis: 30.6;kidney: 43.4;seminal vesicle: 14.3" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 49.2;Loop of henle epithelial cells: 71.1;Papillary tip epithelial cells: 15.9;Proximal tubule cells: 26.3;Renal collecting duct intercalated cells: 23.0;Renal collecting duct principal cells: 40.3;Renal connecting tubule cells: 51.2" "Cell type enhanced" "Detected in some" "Bergmann glia: 3.2;oligodendrocyte: 2.3;oligodendrocyte precursor cell: 1.9" "Group enriched" "Detected in many" 5 "Glioblastoma Multiforme (TCGA): 42.6;Kidney Chromophobe (TCGA): 26.0;Kidney Renal Clear Cell Carcinoma (TCGA): 43.8;Kidney Renal Papillary Cell Carcinoma (TCGA): 58.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 15.9;Uterine cancer: 8.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052792, HPA056039, HPA067151" Enhanced Enhanced Nucleoplasm NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" Nucleoplasm "HPA052792: , HPA056039: , HPA067151: " "unprognostic (3.46e-1)" "unprognostic (1.29e-1)" "unprognostic (2.97e-3)" "unprognostic (3.60e-2)" "validated prognostic favorable (1.90e-4)" "validated prognostic favorable (8.81e-5)" "unprognostic (4.79e-2)" "unprognostic (2.58e-1)" "unprognostic (1.60e-1)" "unprognostic (1.88e-1)" "unprognostic (9.47e-2)" POU3F4 "BRN4, DFN3, DFNX2, OTF9" ENSG00000196767 "POU class 3 homeobox 4" X 83508290-83512127 "Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "brain: 19.9" "Cell type enhanced" "Detected in some" "Astrocytes: 7.8;Bergmann glia: 22.4;Brain inhibitory neurons: 14.6;Ependymal cells: 9.3;Oligodendrocyte progenitor cells: 6.7;Renal collecting duct intercalated cells: 5.1;Renal collecting duct principal cells: 13.2" "Cell type enhanced" "Detected in many" "Bergmann glia: 21.0;CGE interneuron: 21.3;eccentric medium spiny neuron: 17.9;medium spiny neuron: 25.9" "Group enriched" "Detected in some" 18 "Glioblastoma Multiforme (TCGA): 10.5;Kidney Chromophobe (TCGA): 5.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Brain cancer: 1.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA062295 Supported Nucleoplasm NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 35: Neurons - Synaptic function & neurogenesis" Nucleoplasm "HPA062295: " "unprognostic (9.94e-2)" "unprognostic (6.79e-3)" "unprognostic (2.29e-1)" POU4F1 "BRN3A, RDC-1" ENSG00000152192 "POU class 4 homeobox 1" Q01851 13 78598362-78603552 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "retina: 2.4" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 3.3;Early primary spermatocytes: 2.8;Mesothelial cells: 4.1;Myosatellite cells: 10.4;Neuroendocrine cells: 1.7;Oocytes: 9.2;pDCs: 3.2;Retinal ganglion cells: 3.9;Sertoli cells: 2.2;Undifferentiated spermatogonia: 2.3" "Group enriched" "Detected in some" 4 "astrocyte: 2.9;committed oligodendrocyte precursor: 4.0;splatter: 2.4" "Low cancer specificity" "Detected in single" "Group enriched" "Detected in many" 4 "medulla oblongata: 20.3;midbrain: 11.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Leukemia: 9.4;Sarcoma: 10.0" "Testis - Spermatocytes" "Group enriched" "Detected in some" 23 "midbrain: 2.5;pons and medulla: 2.1;thalamus: 2.2" "Region enhanced" "Detected in some" "medulla oblongata: 4.8" HPA068024 Enhanced Approved NA NA "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" 4 "HPA068024: " "unprognostic (3.28e-2)" "unprognostic (2.54e-2)" "unprognostic (3.50e-1)" "unprognostic (8.67e-2)" POU4F2 "Brn-3b, BRN3B" ENSG00000151615 "POU class 4 homeobox 2" Q12837 4 146638893-146642474 "Predicted intracellular proteins, Transcription factors" "Apoptosis, Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "testis: 1.0" "Cell type enriched" "Detected in some" 8 "Retinal ganglion cells: 15.5" "Cell type enriched" "Detected in single" 9 "lower rhombic lip: 6.2" "Not detected" "Not detected" "Group enriched" "Detected in some" 22 "medulla oblongata: 6.5;midbrain: 16.7;pons: 10.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 1.3;Gastric cancer: 2.6" "Testis - Early spermatids" "Region enriched" "Detected in single" 6 "midbrain: 4.4" "Low region specificity" "Detected in many" NA NA "Cluster 47: Testis - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 109: Neurons - Neuronal signaling" 64 POU4F3 "BRN3C, DFNA15, DFNA42, DFNA52" ENSG00000091010 "POU class 4 homeobox 3" Q15319 5 146338839-146341728 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 14 "Mesothelial cells: 6.6" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Bladder Urothelial Carcinoma (TCGA): 2.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 31 "lung cancer: 6.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA038215 Uncertain Supported Nucleoplasm NA NA "Cluster 46: Brainstem - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 13 Nucleoplasm "HPA038215: " "potential prognostic unfavorable (7.29e-4)" POU5F1 "MGC22487, OCT-4, OCT3, Oct3/4, Oct4, OTF3" ENSG00000204531 "POU class 5 homeobox 1" Q01860 6 31164337-31180731 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 16.8" "Cell type enhanced" "Detected in some" "Endometrial glandular cells: 21.7;Endometrial luminal cells: 21.7;Loop of henle epithelial cells: 70.1;Papillary tip epithelial cells: 56.4;Proximal tubule cells: 146.8;Renal collecting duct intercalated cells: 106.3;Renal collecting duct principal cells: 78.1;Renal connecting tubule cells: 23.5" "Low cell type specificity" "Detected in some" "Cancer enriched" "Detected in many" 17 "Testicular Germ Cell Tumor (TCGA): 400.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 19 "testis cancer: 264.4" "CAB025600, CAB026380, HPA058267, CAB079773" Approved Supported Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 60: Stomach - Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 88: Proximal tubular cells - Transmembrane transport" 25 Nucleoplasm "Mitochondria, Cytosol" "CAB025600: , CAB026380: , CAB079773: , HPA058267: " "unprognostic (1.57e-1)" "unprognostic (4.47e-2)" "unprognostic (1.77e-1)" "unprognostic (4.58e-3)" "unprognostic (8.31e-2)" "unprognostic (1.43e-1)" "unprognostic (1.09e-2)" "unprognostic (8.94e-2)" "unprognostic (1.67e-1)" "unprognostic (8.64e-2)" "unprognostic (1.27e-1)" "unprognostic (3.94e-2)" "unprognostic (3.74e-2)" "unprognostic (7.49e-2)" "unprognostic (5.23e-2)" "unprognostic (2.69e-1)" "unprognostic (5.46e-2)" "unprognostic (1.72e-1)" "unprognostic (2.25e-2)" "unprognostic (1.00e-2)" "unprognostic (2.65e-2)" "unprognostic (2.01e-2)" "unprognostic (7.09e-2)" "unprognostic (4.52e-2)" "unprognostic (4.94e-2)" "unprognostic (4.58e-2)" "unprognostic (7.45e-2)" "unprognostic (2.13e-1)" POU5F1B "OTF3C, OTF3P1, POU5F1P1" ENSG00000212993 "POU class 5 homeobox 1B" Q06416 8 127322183-127420066 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 3.9" "Cell type enhanced" "Detected in some" "Breast lactating cells: 1.7;Choroid plexus epithelial cells: 3.3;Endometrial glandular cells: 1.6;Endometrial luminal cells: 2.6;Ependymal cells: 1.8;Parietal cells: 1.8;Respiratory ionocytes: 2.5" "Group enriched" "Detected in some" 11 "choroid plexus epithelial cell: 5.7;ependymal cell: 2.4" "Cancer enhanced" "Detected in many" "Rectum Adenocarcinoma (TCGA): 9.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Lineage enhanced" "Detected in single" "granulocytes: 1.3" "Cancer enhanced" "Detected in some" "colorectal cancer: 6.4" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells" HPA058267 Supported Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 48: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" Nucleoplasm "Mitochondria, Cytosol" "HPA058267: " "unprognostic (2.60e-1)" "unprognostic (3.36e-3)" "unprognostic (1.23e-1)" "unprognostic (3.41e-1)" "potential prognostic favorable (3.01e-4)" "unprognostic (1.36e-1)" "potential prognostic favorable (8.29e-5)" "potential prognostic favorable (1.41e-6)" "unprognostic (1.17e-2)" "unprognostic (1.26e-1)" "unprognostic (1.11e-1)" "unprognostic (5.87e-1)" "unprognostic (8.05e-3)" "unprognostic (7.61e-2)" "unprognostic (6.72e-2)" "unprognostic (1.13e-2)" POU5F2 "FLJ25680, SPRM-1" ENSG00000248483 "POU domain class 5, transcription factor 2" Q8N7G0 5 93733220-93741600 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "testis: 1.8" "Cell type enriched" "Detected in single" 7 "Paneth cells: 3.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" HPA077615 Enhanced Approved Nucleoplasm NA NA "Cluster 47: Testis - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 56: Non-specific - Sensory perception" "Cluster 15: Non-specific - Protein processing" 1 Nucleoplasm "HPA077615: " "unprognostic (2.51e-2)" "unprognostic (1.59e-1)" "unprognostic (5.24e-3)" "unprognostic (1.60e-2)" POU6F1 "BRN5, MPOU, TCFB1" ENSG00000184271 "POU class 6 homeobox 1" 12 51186936-51218062 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 6.7" "Cell type enhanced" "Detected in many" "Lactotrophs: 52.4;Thyrotrophs: 56.5" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 6.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047021, HPA050411" Enhanced Supported "Nuclear bodies,Actin filaments" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 37: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 7: Non-specific - Transcription" "Nuclear bodies" "Actin filaments" "HPA047021: , HPA050411: " "unprognostic (2.87e-2)" "unprognostic (1.02e-2)" "unprognostic (2.01e-1)" "unprognostic (2.03e-1)" "unprognostic (2.38e-1)" "potential prognostic favorable (1.29e-7)" "unprognostic (3.29e-3)" "unprognostic (9.74e-2)" "unprognostic (2.97e-2)" "unprognostic (1.22e-1)" "unprognostic (3.79e-2)" "unprognostic (1.00e-1)" "unprognostic (9.87e-2)" "unprognostic (5.46e-2)" "unprognostic (3.97e-2)" "unprognostic (1.14e-1)" "unprognostic (3.29e-1)" "unprognostic (1.19e-1)" POU6F2 RPF-1 ENSG00000106536 "POU class 6 homeobox 2" P78424 7 38977909-39493095 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.2" "Cell type enhanced" "Detected in many" "Adipocytes: 79.9;Astrocytes: 131.5;Brain excitatory neurons: 105.9;Oligodendrocyte progenitor cells: 349.5;Pancreatic duct cells: 168.4;Pancreatic islet cells: 198.9;Retinal amacrine cells: 382.7;Retinal ganglion cells: 239.5" "Cell type enhanced" "Detected in all" "deep-layer corticothalamic and 6b: 415.1;deep-layer intratelencephalic: 421.4;oligodendrocyte precursor cell: 382.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "testis cancer: 1.4" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 35: Neurons - Synaptic function & neurogenesis" 103 "unprognostic (1.44e-1)" "unprognostic (2.95e-3)" PP2D1 "C3orf48, FLJ25449" ENSG00000183977 "Protein phosphatase 2C like domain containing 1" A8MPX8 3 19979961-20012267 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 12 "bone marrow: 1.8;testis: 6.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 60.1;Early spermatids: 527.2;Epicardial cells: 127.4;Late primary spermatocytes: 223.3;Late spermatids: 475.7" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA036870, HPA066083" Enhanced Uncertain "Nucleoplasm,Intermediate filaments" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 37: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" Nucleoplasm "Intermediate filaments" "HPA036870: , HPA066083: " "unprognostic (4.40e-2)" PPA1 "IOPPP, PP, PP1, Ppase, SID6-8061" ENSG00000180817 "Inorganic pyrophosphatase 1" Q15181 10 70202835-70233911 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 1223.0;Esophageal basal cells: 833.1;Gastric progenitor cells: 930.5;Müller glia: 951.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019878, HPA020096" Supported Supported Vesicles NA NA 650000 "Cluster 33: Non-specific - ATP binding" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 45: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 11: Muller glia cells - Retinal homeostasis" 15 Vesicles "HPA019878: , HPA020096: " "unprognostic (1.03e-3)" "unprognostic (8.85e-3)" "unprognostic (2.48e-1)" "potential prognostic unfavorable (7.28e-5)" "unprognostic (1.90e-1)" "unprognostic (1.12e-1)" "unprognostic (2.27e-1)" "potential prognostic favorable (5.54e-7)" "unprognostic (4.23e-2)" "unprognostic (2.09e-1)" "potential prognostic favorable (4.40e-4)" "unprognostic (2.94e-1)" "unprognostic (1.37e-1)" "unprognostic (1.09e-3)" "unprognostic (9.86e-3)" "unprognostic (1.17e-2)" "unprognostic (3.14e-2)" "unprognostic (1.08e-1)" "unprognostic (2.32e-2)" "unprognostic (2.26e-2)" "unprognostic (3.46e-1)" "potential prognostic unfavorable (3.66e-4)" "unprognostic (2.46e-1)" "unprognostic (5.96e-3)" "unprognostic (3.00e-2)" "unprognostic (2.55e-2)" "unprognostic (3.18e-1)" "unprognostic (1.23e-1)" "unprognostic (3.35e-1)" "unprognostic (1.41e-1)" "unprognostic (6.60e-3)" PPA2 FLJ20459 ENSG00000138777 "Inorganic pyrophosphatase 2" Q9H2U2 4 105369077-105474067 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Uterine Corpus Endometrial Carcinoma (TCGA): 152.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030888, HPA031671, HPA031672" Supported Supported Mitochondria NA NA 85000 "Cluster 13: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 7: Non-specific - Transcription" 10 Mitochondria "HPA030888: , HPA031671: , HPA031672: " "unprognostic (8.26e-2)" "unprognostic (1.49e-2)" "unprognostic (1.74e-2)" "unprognostic (2.39e-1)" "potential prognostic favorable (8.48e-4)" "unprognostic (2.62e-2)" "unprognostic (6.40e-2)" "unprognostic (5.35e-2)" "unprognostic (4.50e-2)" "unprognostic (9.00e-3)" "potential prognostic unfavorable (9.62e-4)" "unprognostic (2.93e-2)" "potential prognostic favorable (7.94e-5)" "unprognostic (1.35e-1)" "unprognostic (9.56e-2)" "unprognostic (3.04e-1)" "unprognostic (3.31e-2)" "unprognostic (2.35e-2)" "unprognostic (1.62e-2)" "unprognostic (8.87e-2)" "unprognostic (1.59e-2)" "unprognostic (2.38e-3)" "unprognostic (3.66e-1)" "unprognostic (1.22e-1)" "unprognostic (5.62e-2)" "unprognostic (2.11e-1)" "unprognostic (8.55e-2)" "unprognostic (9.71e-2)" "unprognostic (1.10e-2)" "unprognostic (3.57e-2)" "unprognostic (4.79e-2)" PPAN "BXDC3, SSF, SSF1, SSF2" ENSG00000130810 "Peter pan homolog" Q9NQ55 19 10106362-10112012 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Astrocytes: 4.7;Bergmann glia: 5.2;Brain excitatory neurons: 8.4;Brain inhibitory neurons: 6.8;Choroid plexus epithelial cells: 3.9;Ependymal cells: 4.1;Microglia: 7.5;Oligodendrocyte progenitor cells: 4.6;Oligodendrocytes: 5.6;Other brain neurons: 8.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043265 Approved NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 98: Neurons - Neurotransmission & signaling" 15 "HPA043265: " "unprognostic (5.12e-1)" "unprognostic (3.88e-1)" "unprognostic (2.41e-2)" "unprognostic (1.40e-1)" "unprognostic (2.42e-3)" "unprognostic (4.64e-1)" "unprognostic (2.73e-1)" "unprognostic (9.39e-3)" "unprognostic (3.10e-2)" "potential prognostic unfavorable (6.52e-4)" "potential prognostic unfavorable (2.64e-4)" "unprognostic (1.60e-2)" "unprognostic (1.21e-1)" "unprognostic (8.53e-3)" "unprognostic (1.69e-2)" "unprognostic (3.44e-2)" "unprognostic (1.21e-3)" "unprognostic (4.07e-2)" "unprognostic (7.64e-3)" "unprognostic (2.28e-3)" "unprognostic (1.35e-2)" "unprognostic (2.20e-1)" "unprognostic (4.30e-1)" "unprognostic (2.66e-3)" "unprognostic (2.85e-2)" "unprognostic (1.17e-1)" "unprognostic (1.41e-1)" "unprognostic (4.42e-2)" "unprognostic (6.13e-2)" "unprognostic (2.79e-1)" "unprognostic (1.80e-1)" PPAN-P2RY11 ENSG00000243207 "PPAN-P2RY11 readthrough" 19 10106223-10114780 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in single" "Cholangiocytes: 2.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" HPA014232 Uncertain NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 49: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 82: Dendritic cells - Antigen presentation" 2 "HPA014232: " "unprognostic (1.89e-2)" "unprognostic (1.63e-1)" "unprognostic (7.76e-2)" "unprognostic (5.41e-2)" "unprognostic (6.60e-2)" "unprognostic (6.75e-2)" "unprognostic (4.22e-2)" "unprognostic (3.03e-2)" "unprognostic (7.06e-2)" "unprognostic (8.00e-3)" "unprognostic (3.16e-2)" "unprognostic (6.68e-2)" "unprognostic (1.50e-1)" "potential prognostic favorable (2.11e-4)" "unprognostic (2.02e-2)" "unprognostic (3.64e-2)" "unprognostic (7.36e-3)" "unprognostic (1.18e-2)" "unprognostic (2.50e-2)" "unprognostic (2.14e-1)" "unprognostic (5.26e-2)" "unprognostic (1.87e-1)" PPARA "hPPAR, NR1C1, PPAR" ENSG00000186951 "Peroxisome proliferator activated receptor alpha" Q07869 22 46150521-46243755 "FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors, Transporters" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 39.7" "Cell type enhanced" "Detected in many" "Enterocytes: 313.3;Hepatocytes: 326.6;Proximal tubule cells: 571.0;Rod photoreceptor cells: 680.1" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 180.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "eosinophil: 9.8;plasmacytoid DC: 2.9" "Group enriched" "Detected in many" 5 "dendritic cells: 2.9;granulocytes: 9.8" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066941, CAB075701" Supported Uncertain "Nucleoli fibrillar center,Nuclear bodies,Primary cilium,Centriolar satellite,Basal body" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 76: Non-specific - Metabolism" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 79: Photoreceptor cells - Phototransduction" 38 "Primary cilium" "Nucleoli fibrillar center, Nuclear bodies, Centriolar satellite, Basal body" "CAB075701: , HPA066941: " "unprognostic (1.79e-2)" "unprognostic (4.00e-1)" "unprognostic (1.41e-1)" "unprognostic (5.67e-2)" "unprognostic (5.82e-2)" "unprognostic (5.52e-2)" "unprognostic (4.53e-3)" "unprognostic (4.96e-1)" "unprognostic (3.28e-2)" "unprognostic (2.48e-2)" "validated prognostic favorable (7.88e-8)" "validated prognostic favorable (1.63e-5)" "unprognostic (8.96e-3)" "unprognostic (1.25e-1)" "unprognostic (4.16e-3)" "unprognostic (7.48e-2)" "unprognostic (2.23e-1)" "unprognostic (2.52e-1)" "unprognostic (6.33e-2)" "unprognostic (3.15e-2)" "unprognostic (7.51e-2)" "unprognostic (2.11e-2)" "unprognostic (1.30e-1)" "unprognostic (3.16e-1)" "unprognostic (1.90e-3)" "unprognostic (3.39e-2)" "unprognostic (1.69e-1)" "unprognostic (6.15e-2)" "unprognostic (1.27e-1)" "unprognostic (3.87e-2)" "unprognostic (1.32e-1)" PPARD "FAAR, NR1C2, NUC1, NUCII, PPARB" ENSG00000112033 "Peroxisome proliferator activated receptor delta" Q03181 6 35342558-35428191 "FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 278.2;Mast cells: 268.2;monocytes: 246.0;Pancreatic acinar cells: 320.4;Syncytiotrophoblasts: 371.1;Urothelial cells: 281.6" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 227.5;endothelial cell: 368.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB017635 Approved NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 47: Endothelial cells - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 18 "CAB017635: " "unprognostic (8.50e-2)" "unprognostic (5.02e-3)" "unprognostic (4.09e-2)" "unprognostic (5.54e-2)" "unprognostic (9.75e-2)" "unprognostic (2.61e-2)" "unprognostic (8.50e-2)" "unprognostic (1.73e-1)" "unprognostic (1.22e-1)" "unprognostic (2.16e-3)" "unprognostic (4.58e-2)" "unprognostic (2.65e-2)" "unprognostic (1.32e-2)" "potential prognostic unfavorable (4.54e-4)" "unprognostic (4.26e-1)" "unprognostic (6.27e-3)" "unprognostic (7.06e-3)" "unprognostic (2.81e-1)" "unprognostic (2.83e-1)" "unprognostic (1.55e-1)" "unprognostic (6.79e-2)" "unprognostic (2.45e-2)" "unprognostic (9.83e-3)" "unprognostic (4.00e-3)" "unprognostic (1.80e-1)" "unprognostic (2.27e-2)" "unprognostic (1.60e-1)" "unprognostic (1.39e-1)" "unprognostic (2.09e-1)" "unprognostic (1.31e-1)" "unprognostic (3.31e-1)" PPARG "NR1C3, PPARG1, PPARG2, PPARgamma" ENSG00000132170 "Peroxisome proliferator activated receptor gamma" P37231 3 12287368-12434356 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Cancer-related genes, Diabetes mellitus, Disease variant, FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 153.2;breast: 83.9" "Cell type enhanced" "Detected in many" "Adipocytes: 2246.8;Colonocytes: 505.7;Extravillous trophoblasts: 539.7;Foveolar cells: 753.3;Papillary tip epithelial cells: 818.5;Prostatic club cells: 766.8;Prostatic hillock cells: 990.2;Urothelial cells: 4300.8" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Bladder Urothelial Carcinoma (TCGA): 111.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Macrophages, Skeletal muscle - Endothelial cells, Stomach - Gastric mucous cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" "CAB004282, HPA051239, HPA063663" Approved Enhanced Nucleoplasm,Vesicles NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 37: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 69: Urothelial cells - Basic cellular functions" 99 "Nucleoplasm, Vesicles" "CAB004282: , HPA051239: , HPA063663: " "unprognostic (7.28e-3)" "unprognostic (1.03e-2)" "unprognostic (3.95e-3)" "unprognostic (1.01e-2)" "unprognostic (4.68e-2)" "potential prognostic favorable (5.10e-4)" "unprognostic (4.27e-3)" "unprognostic (2.25e-1)" "unprognostic (5.42e-3)" "unprognostic (2.40e-2)" "validated prognostic favorable (7.99e-8)" "validated prognostic favorable (2.54e-5)" "unprognostic (6.14e-2)" "validated prognostic unfavorable (8.15e-7)" "validated prognostic unfavorable (8.34e-6)" "unprognostic (2.35e-2)" "unprognostic (1.20e-1)" "unprognostic (2.50e-1)" "unprognostic (4.17e-2)" "unprognostic (1.04e-1)" "unprognostic (1.39e-2)" "unprognostic (1.70e-2)" "unprognostic (5.10e-1)" "unprognostic (5.82e-2)" "unprognostic (6.67e-3)" "unprognostic (2.69e-3)" "unprognostic (3.87e-2)" "unprognostic (8.11e-2)" "unprognostic (2.23e-2)" "unprognostic (4.14e-3)" "unprognostic (9.88e-2)" PPARGC1A "PGC-1alpha, PGC1, PGC1A, PPARAGCIalpha, PPARGC1" ENSG00000109819 "PPARG coactivator 1 alpha" Q9UBK2 4 23755041-23904089 "Cancer-related genes, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "Activator, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 41.7" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 469.7;Choroid plexus epithelial cells: 900.3;Conjunctival goblet cells: 509.7;Distal convoluted tubule cells: 802.7;Loop of henle epithelial cells: 581.3;Myonuclei: 525.0;Renal collecting duct intercalated cells: 813.2;Renal connecting tubule cells: 744.6;Salivary basal cells: 549.9;Salivary duct cells: 714.2;Salivary ionocytes: 525.5" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 725.3;mammillary body: 499.5" "Group enriched" "Detected in many" 5 "Kidney Chromophobe (TCGA): 77.1;Kidney Renal Papillary Cell Carcinoma (TCGA): 23.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 12.7" "Heart muscle - Cardiomyocytes, Minor Salivary Gland - Minor salivary gland ductal cells, Skin - Eccrine sweat gland cells, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063176 Supported Nucleoplasm,Cytosol NA NA "Cluster 76: Non-specific - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 36 Nucleoplasm Cytosol "HPA063176: " "unprognostic (8.65e-2)" "unprognostic (1.07e-1)" "potential prognostic favorable (3.39e-4)" "unprognostic (1.91e-1)" "unprognostic (3.88e-2)" "unprognostic (1.29e-2)" "unprognostic (1.11e-2)" "potential prognostic favorable (2.41e-12)" "unprognostic (8.94e-3)" "potential prognostic favorable (2.92e-5)" "potential prognostic favorable (9.95e-6)" "unprognostic (4.25e-3)" "unprognostic (3.13e-1)" "potential prognostic favorable (5.20e-4)" "unprognostic (1.60e-1)" "unprognostic (1.29e-2)" "unprognostic (6.71e-2)" "unprognostic (3.45e-1)" "unprognostic (3.34e-1)" "unprognostic (2.55e-1)" "unprognostic (1.44e-1)" "unprognostic (1.57e-1)" "potential prognostic unfavorable (2.79e-4)" PPARGC1B "PERC, PGC1B, PPARAGCIbeta" ENSG00000155846 "PPARG coactivator 1 beta" Q86YN6 5 149730298-149855022 "Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 11.2" "Cell type enhanced" "Detected in many" "Adipocytes: 99.9;Cardiomyocytes: 230.6;Cone photoreceptor cells: 167.7;Epicardial cells: 122.8;Myonuclei: 284.4;Retinal bipolar cells: 136.0;Rod photoreceptor cells: 128.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 3.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA050543 Supported Nucleoplasm,Cytosol NA Yes "Cluster 40: Monocytes - Innate immune response" "Cluster 61: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 2 Nucleoplasm Cytosol "HPA050543: " "unprognostic (5.65e-2)" "unprognostic (1.60e-1)" "unprognostic (1.25e-2)" "unprognostic (2.34e-2)" "unprognostic (3.29e-2)" "unprognostic (4.81e-2)" "unprognostic (1.94e-2)" "unprognostic (1.21e-2)" "unprognostic (8.85e-2)" "unprognostic (2.08e-1)" "unprognostic (1.77e-1)" "unprognostic (1.77e-1)" "unprognostic (4.97e-2)" "unprognostic (6.84e-2)" "unprognostic (8.23e-3)" "unprognostic (6.98e-3)" "unprognostic (1.23e-1)" "unprognostic (1.20e-1)" "unprognostic (1.59e-1)" "unprognostic (3.06e-1)" "unprognostic (5.71e-3)" "unprognostic (3.21e-1)" "unprognostic (1.62e-2)" "unprognostic (9.25e-2)" "unprognostic (1.33e-1)" "unprognostic (1.02e-3)" PPAT "GPAT, PRAT" ENSG00000128059 "Phosphoribosyl pyrophosphate amidotransferase" Q06203 4 56393362-56435615 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" "Purine biosynthesis" "Allosteric enzyme, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 69.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036091, HPA036092" Approved Approved "Midbody ring" Yes No 7000 "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 17: Non-specific - RNA processing" 9 "Midbody ring" "HPA036091: , HPA036092: " "unprognostic (4.62e-2)" "unprognostic (1.59e-2)" "unprognostic (1.41e-1)" "unprognostic (4.85e-2)" "unprognostic (8.12e-3)" "unprognostic (1.24e-2)" "unprognostic (2.32e-1)" "unprognostic (9.14e-2)" "unprognostic (9.22e-2)" "unprognostic (1.62e-3)" "potential prognostic favorable (7.37e-5)" "unprognostic (6.87e-2)" "unprognostic (2.94e-3)" "potential prognostic unfavorable (4.85e-9)" "unprognostic (1.69e-2)" "unprognostic (1.62e-3)" "potential prognostic unfavorable (5.06e-5)" "unprognostic (2.18e-1)" "unprognostic (1.45e-2)" "unprognostic (2.21e-1)" "unprognostic (7.94e-2)" "unprognostic (1.72e-3)" "unprognostic (5.56e-2)" "unprognostic (1.02e-1)" "unprognostic (4.55e-3)" "unprognostic (2.97e-1)" "unprognostic (5.16e-2)" "unprognostic (2.84e-1)" "unprognostic (1.63e-1)" "potential prognostic unfavorable (1.58e-4)" "unprognostic (9.58e-3)" PPBP "b-TG1, Beta-TG, CTAP3, CTAPIII, CXCL7, LA-PF4, LDGF, MDGF, NAP-2, NAP-2-L1, PBP, SCYB7, TGB, TGB1, THBGB1" ENSG00000163736 "Pro-platelet basic protein" P02775 4 73986439-73988190 "Plasma proteins, Predicted secreted proteins" Chemotaxis "Antibiotic, Antimicrobial, Cytokine, Growth factor, Mitogen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 78.8;lymphoid tissue: 23.3" "Group enriched" "Detected in some" 46 "Megakaryocytes: 49.5;Platelets: 141.1" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "Colon Adenocarcinoma (TCGA): 102.9;Rectum Adenocarcinoma (TCGA): 27.6" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 15 "basophil: 287.2;neutrophil: 86.7" "Lineage enriched" "Detected in all" 23 "granulocytes: 287.2" "Group enriched" "Detected in some" 6 "colorectal cancer: 8.4;lung cancer: 3.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA008354, CAB017624" Supported "Secreted to blood" Cytokine NA NA 24500000 3800000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 47: Platelets - Hemostasis" 6 "CAB017624: , HPA008354: " "potential prognostic unfavorable (6.51e-4)" "unprognostic (7.99e-2)" "unprognostic (3.85e-2)" "unprognostic (9.94e-2)" "unprognostic (1.23e-2)" "unprognostic (3.27e-1)" "unprognostic (2.66e-1)" "unprognostic (2.15e-2)" "unprognostic (2.67e-1)" "unprognostic (1.22e-1)" "unprognostic (1.76e-1)" "unprognostic (2.01e-2)" "unprognostic (2.32e-2)" "unprognostic (1.91e-1)" "unprognostic (8.34e-2)" "unprognostic (1.45e-1)" PPCDC "FLJ14585, MDS018" ENSG00000138621 "Phosphopantothenoylcysteine decarboxylase" Q96CD2 15 75023586-75117462 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Coenzyme A biosynthesis" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 159.4;Neutrophils: 478.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "dendritic cells: 71.6;granulocytes: 153.9;monocytes: 72.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045667 Approved Approved Cytosol NA NA 14000 "Cluster 25: Non-specific - Unknown function" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 6: Non-specific - Immune response" "Cluster 58: Non-specific - Nuclear processes" "Cluster 24: Neutrophils - Innate immunity signal integration" 10 Cytosol "HPA045667: " "unprognostic (1.03e-2)" "unprognostic (3.18e-2)" "unprognostic (3.25e-1)" "unprognostic (1.78e-1)" "unprognostic (2.60e-1)" "unprognostic (2.73e-1)" "unprognostic (1.93e-3)" "unprognostic (1.75e-1)" "unprognostic (8.06e-2)" "unprognostic (3.67e-2)" "validated prognostic favorable (4.02e-5)" "validated prognostic favorable (2.78e-4)" "potential prognostic favorable (9.00e-4)" "unprognostic (1.25e-3)" "unprognostic (2.33e-2)" "unprognostic (9.55e-2)" "unprognostic (5.70e-2)" "unprognostic (2.82e-2)" "unprognostic (1.31e-1)" "unprognostic (1.57e-1)" "unprognostic (7.38e-3)" "unprognostic (7.86e-2)" "potential prognostic unfavorable (8.88e-4)" "unprognostic (3.98e-1)" "unprognostic (2.84e-1)" "unprognostic (1.74e-1)" "unprognostic (7.62e-2)" "unprognostic (2.83e-1)" "unprognostic (5.15e-1)" "unprognostic (1.65e-1)" "unprognostic (9.95e-2)" PPCS FLJ11838 ENSG00000127125 "Phosphopantothenoylcysteine synthetase" Q9HAB8 1 42456117-42473385 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Ligase "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 276.9;Megakaryocytes: 346.2;Parietal cells: 374.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031361, HPA031363" Approved Approved Mitochondria NA NA 120000 "Cluster 25: Non-specific - Unknown function" "Cluster 72: Kidney - Transmembrane transport" "Cluster 21: Non-specific - Metabolism" "Cluster 27: Breast cancer - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 4 Mitochondria "HPA031361: , HPA031363: " "unprognostic (1.08e-1)" "unprognostic (3.87e-1)" "unprognostic (1.14e-2)" "unprognostic (1.65e-1)" "unprognostic (3.92e-2)" "unprognostic (1.27e-1)" "unprognostic (3.46e-3)" "potential prognostic unfavorable (3.55e-5)" "unprognostic (5.06e-3)" "unprognostic (4.37e-3)" "potential prognostic favorable (5.22e-5)" "unprognostic (8.90e-2)" "unprognostic (7.66e-2)" "potential prognostic unfavorable (1.15e-4)" "unprognostic (2.51e-2)" "unprognostic (9.13e-2)" "unprognostic (1.64e-1)" "unprognostic (4.40e-2)" "unprognostic (3.37e-3)" "unprognostic (4.92e-2)" "unprognostic (1.42e-1)" "potential prognostic unfavorable (2.91e-4)" "unprognostic (2.96e-1)" "unprognostic (4.90e-2)" "unprognostic (8.69e-2)" "unprognostic (6.54e-2)" "unprognostic (2.20e-2)" "unprognostic (1.43e-1)" "unprognostic (1.22e-1)" "unprognostic (2.10e-1)" "unprognostic (2.61e-1)" PPDPF "C20orf149, dJ697K14.9, exdpf" ENSG00000125534 "Pancreatic progenitor cell differentiation and proliferation factor" Q9H3Y8 20 63520765-63522206 "Predicted intracellular proteins" Differentiation "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Esophageal apical cells: 18164.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "eosinophil: 26.0" "Lineage enriched" "Detected in all" 4 "granulocytes: 26.0" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040929 Approved Nucleoplasm,Nucleoli,Microtubules Yes No "Cluster 19: Eosinophils - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 84: Apical squamous epithelium - Cornification" 5 "Nucleoplasm, Microtubules" Nucleoli "HPA040929: " "unprognostic (3.45e-3)" "unprognostic (1.57e-1)" "unprognostic (6.75e-2)" "unprognostic (8.61e-2)" "unprognostic (2.12e-1)" "unprognostic (1.21e-3)" "unprognostic (2.59e-2)" "unprognostic (2.26e-2)" "unprognostic (5.21e-2)" "unprognostic (1.11e-1)" "unprognostic (2.85e-1)" "unprognostic (1.21e-1)" "potential prognostic favorable (5.21e-4)" "unprognostic (4.81e-2)" "unprognostic (1.98e-2)" "unprognostic (9.27e-2)" "unprognostic (1.62e-1)" "unprognostic (7.81e-3)" "unprognostic (2.27e-1)" "unprognostic (2.98e-1)" "unprognostic (3.01e-1)" "unprognostic (4.02e-2)" "unprognostic (5.55e-2)" "unprognostic (2.64e-1)" "unprognostic (4.71e-2)" "unprognostic (1.07e-1)" "unprognostic (1.10e-1)" "unprognostic (3.68e-2)" "unprognostic (5.66e-2)" "unprognostic (8.49e-2)" "unprognostic (2.20e-2)" PPDPFL C8orf22 ENSG00000168333 "Pancreatic progenitor cell differentiation and proliferation factor like" Q8WWR9 8 49054311-49076093 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "skeletal muscle: 741.2" "Group enriched" "Detected in some" 4 "Conjunctival goblet cells: 93.2;Myonuclei: 271.1" "Cell type enhanced" "Detected in single" "astrocyte: 1.0" "Cancer enriched" "Detected in some" 7 "Kidney Renal Clear Cell Carcinoma (TCGA): 16.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Leukemia: 1.0" HPA060329 Uncertain NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 30: White matter - Myelination" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" "HPA060329: " "unprognostic (1.77e-2)" "unprognostic (8.99e-2)" "potential prognostic unfavorable (1.67e-4)" "unprognostic (1.28e-1)" PPEF1 "PPEF, PPP7CA" ENSG00000086717 "Protein phosphatase with EF-hand domain 1" O14829 X 18675909-18827921 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 8.9;breast: 3.9;testis: 13.1" "Cell type enhanced" "Detected in many" "Early spermatids: 67.1;Late primary spermatocytes: 42.1;Late spermatids: 257.1;Neutrophil progenitors: 28.2;Sertoli cells: 19.9" "Cell type enhanced" "Detected in many" "miscellaneous: 36.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Neuroblastoma: 5.4;Uterine cancer: 1.6" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA034577 Uncertain "Plasma membrane,Cytokinetic bridge" Yes NA "Cluster 67: Testis - Mixed function" "Cluster 30: White matter - Myelination" "Cluster 1: Neuronal - Visual perception" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 5 "Plasma membrane" "Cytokinetic bridge" "HPA034577: " "unprognostic (8.78e-2)" "unprognostic (2.91e-2)" "potential prognostic unfavorable (2.88e-4)" "unprognostic (4.87e-2)" "unprognostic (3.72e-1)" "unprognostic (1.47e-1)" "unprognostic (7.69e-2)" "unprognostic (1.00e-1)" PPEF2 PPP7CB ENSG00000156194 "Protein phosphatase with EF-hand domain 2" O14830 4 75859864-75902571 "Enzymes, Predicted intracellular proteins" "Sensory transduction, Vision" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 249 "retina: 221.1" "Cell type enriched" "Detected in some" 4 "Rod photoreceptor cells: 1892.1" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in single" "Uterine Corpus Endometrial Carcinoma (TCGA): 1.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 42: Retina - Visual perception" "Cluster 79: Photoreceptor cells - Phototransduction" 1 PPFIA1 "LIP.1, LIPRIN" ENSG00000131626 "PTPRF interacting protein alpha 1" Q13136 11 70270690-70385312 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 245.1;Bergmann glia: 208.6;Choroid plexus epithelial cells: 287.4;Distal convoluted tubule cells: 127.8;Early spermatids: 155.7;Microglia: 127.9;Proximal tubule cells: 138.7;Renal collecting duct intercalated cells: 145.9;Renal connecting tubule cells: 131.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017032, HPA042271" Uncertain Supported "Focal adhesion sites,Cytosol" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 15: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 61 Cytosol "Focal adhesion sites" "CAB017032: , HPA042271: " "unprognostic (4.91e-1)" "unprognostic (6.85e-2)" "unprognostic (2.02e-2)" "unprognostic (8.93e-3)" "unprognostic (1.77e-1)" "unprognostic (1.04e-2)" "unprognostic (2.41e-1)" "unprognostic (2.47e-2)" "potential prognostic unfavorable (3.31e-4)" "unprognostic (2.07e-1)" "potential prognostic favorable (9.74e-7)" "unprognostic (1.40e-1)" "unprognostic (2.07e-1)" "unprognostic (5.32e-2)" "unprognostic (1.27e-1)" "unprognostic (1.38e-2)" "unprognostic (2.24e-2)" "unprognostic (7.71e-2)" "unprognostic (2.25e-1)" "unprognostic (4.42e-3)" "unprognostic (2.41e-2)" "unprognostic (1.21e-3)" "potential prognostic unfavorable (2.25e-5)" "unprognostic (1.10e-1)" "unprognostic (2.24e-3)" "unprognostic (1.80e-2)" "unprognostic (2.06e-1)" "unprognostic (1.50e-1)" "unprognostic (1.68e-1)" "unprognostic (1.66e-1)" "unprognostic (3.79e-3)" PPFIA2 ENSG00000139220 "PTPRF interacting protein alpha 2" O75334 12 81257975-81759553 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 34.3;retina: 46.4" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 712.7;Brain excitatory neurons: 1143.9;Brain inhibitory neurons: 979.5;Cone photoreceptor cells: 602.4;Corticotrophs: 1523.5;Ependymal cells: 862.3;Lactotrophs: 448.1;Oligodendrocyte progenitor cells: 841.3;Oligodendrocytes: 521.1;Other brain neurons: 975.2;Retinal amacrine cells: 1392.7;Retinal bipolar cells: 491.0;Retinal ganglion cells: 459.7;Rod photoreceptor cells: 880.4;Thyrotrophs: 964.8" "Cell type enhanced" "Detected in all" "hippocampal dentate gyrus: 4705.4" "Group enriched" "Detected in some" 4 "Glioblastoma Multiforme (TCGA): 4.2;Prostate Adenocarcinoma (TCGA): 7.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Neuroblastoma: 5.6;prostate cancer: 18.4" "Adrenal gland - Adrenal medulla cells, Pituitary gland - Corticotropes, Prostate - Smooth muscle cells, Spleen - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" 7 "unprognostic (3.39e-1)" "unprognostic (3.32e-1)" "unprognostic (6.39e-2)" "potential prognostic favorable (2.37e-4)" "unprognostic (3.02e-3)" "unprognostic (4.58e-2)" "unprognostic (1.34e-1)" "unprognostic (4.31e-2)" "unprognostic (8.61e-2)" "unprognostic (1.19e-2)" PPFIA3 "KIAA0654, LPNA3, MGC126567, MGC126569" ENSG00000177380 "PTPRF interacting protein alpha 3" O75145 19 49119544-49151026 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 60.7;pituitary gland: 44.3;skin 1: 41.4" "Cell type enhanced" "Detected in many" "Lactotrophs: 64.1;Retinal amacrine cells: 69.0;Retinal bipolar cells: 44.9;Retinal ganglion cells: 54.1;Retinal horizontal cells: 72.1;Somatotrophs: 47.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043567, HPA050340" Enhanced NA NA "Cluster 2: Non-specific - Mixed function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 109: Neurons - Neuronal signaling" 9 "HPA043567: , HPA050340: " "unprognostic (1.43e-1)" "potential prognostic unfavorable (5.65e-4)" "unprognostic (1.51e-1)" "unprognostic (1.07e-1)" "unprognostic (4.14e-2)" "unprognostic (6.68e-2)" "unprognostic (1.38e-2)" "unprognostic (2.44e-1)" "potential prognostic favorable (2.87e-4)" "unprognostic (1.79e-1)" "potential prognostic unfavorable (9.89e-5)" "unprognostic (2.20e-3)" "unprognostic (1.12e-1)" "potential prognostic unfavorable (8.22e-6)" "unprognostic (1.07e-1)" "unprognostic (1.38e-1)" "unprognostic (1.54e-1)" "unprognostic (1.28e-1)" "unprognostic (3.36e-2)" "unprognostic (3.59e-3)" "unprognostic (1.59e-1)" "unprognostic (3.47e-3)" "unprognostic (9.82e-2)" "unprognostic (9.69e-2)" "unprognostic (2.50e-1)" "unprognostic (1.65e-1)" "unprognostic (7.94e-3)" "unprognostic (3.45e-3)" "unprognostic (2.39e-1)" "unprognostic (6.85e-2)" "unprognostic (1.22e-1)" PPFIA4 ENSG00000143847 "PTPRF interacting protein alpha 4" O75335 1 203026491-203078740 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 96.8" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 91.2;Brain inhibitory neurons: 48.4;Myonuclei: 43.9;Other brain neurons: 29.5;Podocytes: 169.6;Retinal amacrine cells: 50.3;Retinal ganglion cells: 50.2;Thymic myoid cells: 24.5" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 6.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal medulla cells, Heart muscle - Cardiomyocytes, Kidney - Podocytes, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053419, HPA054132" Enhanced NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 27: Cerebellum - Synaptic function" "Cluster 37: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 3 "HPA053419: , HPA054132: " "unprognostic (5.28e-2)" "unprognostic (3.03e-2)" "unprognostic (8.38e-2)" "unprognostic (1.37e-1)" "unprognostic (9.65e-2)" "unprognostic (1.47e-1)" "unprognostic (2.63e-1)" "unprognostic (2.34e-2)" "unprognostic (2.56e-1)" "unprognostic (9.59e-3)" "unprognostic (2.38e-1)" "unprognostic (1.04e-2)" "unprognostic (4.46e-2)" "unprognostic (2.75e-1)" "potential prognostic unfavorable (7.85e-4)" "unprognostic (1.02e-1)" "unprognostic (5.71e-3)" "unprognostic (2.17e-1)" PPFIBP1 "hSGT2, hSgt2p, L2, SGT2" ENSG00000110841 "PPFIA binding protein 1" Q86W92 12 27523431-27695564 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 560.6;Lymphatic endothelial cells: 1720.5;Proximal tubule cells: 625.9" "Cell type enhanced" "Detected in all" "endothelial cell: 1073.5;fibroblast: 894.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 2.7" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001924, HPA071162" Uncertain Enhanced "Plasma membrane" NA NA "Cluster 18: Non-specific - Translation" "Cluster 35: Non-specific - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 47 "Plasma membrane" "HPA001924: , HPA071162: " "unprognostic (1.76e-1)" "unprognostic (1.63e-1)" "unprognostic (3.30e-1)" "unprognostic (5.49e-3)" "unprognostic (6.75e-2)" "unprognostic (6.21e-3)" "unprognostic (1.53e-1)" "unprognostic (6.90e-2)" "unprognostic (7.11e-2)" "unprognostic (3.09e-3)" "validated prognostic favorable (1.72e-7)" "validated prognostic favorable (3.78e-4)" "unprognostic (3.53e-3)" "unprognostic (9.94e-2)" "unprognostic (4.86e-2)" "potential prognostic unfavorable (8.35e-4)" "unprognostic (2.24e-2)" "unprognostic (8.92e-3)" "unprognostic (3.65e-2)" "unprognostic (2.49e-3)" "unprognostic (4.77e-2)" "unprognostic (2.22e-3)" "unprognostic (3.35e-3)" "unprognostic (6.98e-2)" "unprognostic (1.86e-1)" "unprognostic (9.36e-2)" "unprognostic (2.52e-2)" "unprognostic (1.90e-1)" "unprognostic (2.37e-1)" "unprognostic (1.14e-1)" "unprognostic (1.60e-1)" PPFIBP2 Cclp1 ENSG00000166387 "PPFIA binding protein 2" Q8ND30 11 7513298-7657127 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 252.9;Endometrial glandular cells: 255.4;Renal collecting duct intercalated cells: 287.4" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 176.1;committed oligodendrocyte precursor: 146.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Outer root sheath cells, Spleen - B-cells (Spleen), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001935, HPA003911" Enhanced Approved Mitochondria NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 55: Lymphoma - Immune response" "Cluster 51: Secretory epithelial cells - Mixed function" 7 Mitochondria "HPA001935: , HPA003911: " "unprognostic (9.43e-3)" "unprognostic (4.80e-3)" "unprognostic (6.07e-2)" "unprognostic (4.16e-2)" "unprognostic (1.84e-1)" "unprognostic (1.20e-1)" "unprognostic (2.89e-1)" "unprognostic (2.88e-1)" "unprognostic (1.13e-3)" "unprognostic (2.40e-1)" "validated prognostic favorable (5.04e-9)" "validated prognostic favorable (1.36e-5)" "unprognostic (2.91e-1)" "unprognostic (5.24e-2)" "unprognostic (4.79e-2)" "potential prognostic favorable (5.32e-5)" "unprognostic (1.29e-1)" "unprognostic (1.09e-1)" "unprognostic (2.85e-2)" "unprognostic (1.85e-1)" "unprognostic (1.30e-1)" "unprognostic (1.61e-1)" "unprognostic (7.26e-2)" "unprognostic (3.52e-1)" "potential prognostic favorable (1.55e-4)" "unprognostic (3.24e-2)" "unprognostic (5.13e-2)" "unprognostic (2.75e-1)" "unprognostic (2.55e-1)" "unprognostic (1.42e-1)" "unprognostic (3.46e-1)" PPHLN1 ENSG00000134283 "Periphilin 1" Q8NEY8 12 42238447-42459715 "Predicted intracellular proteins" "Keratinization, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038902, HPA038903" Enhanced Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 31: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 17 Nucleoplasm "Golgi apparatus" "HPA038902: , HPA038903: " "unprognostic (8.95e-2)" "unprognostic (4.74e-2)" "unprognostic (5.08e-3)" "unprognostic (8.73e-2)" "unprognostic (2.06e-2)" "unprognostic (7.58e-2)" "unprognostic (1.08e-1)" "unprognostic (1.72e-2)" "unprognostic (8.71e-3)" "unprognostic (4.07e-2)" "potential prognostic favorable (1.36e-4)" "unprognostic (1.99e-1)" "unprognostic (3.33e-1)" "potential prognostic unfavorable (3.43e-5)" "unprognostic (1.26e-3)" "unprognostic (2.74e-2)" "unprognostic (1.09e-2)" "unprognostic (1.39e-1)" "unprognostic (8.56e-2)" "unprognostic (7.28e-2)" "unprognostic (2.34e-1)" "unprognostic (2.64e-3)" "unprognostic (6.77e-3)" "unprognostic (7.47e-3)" "unprognostic (2.68e-2)" "unprognostic (5.07e-2)" "unprognostic (5.17e-3)" "unprognostic (6.40e-2)" "unprognostic (3.63e-1)" "unprognostic (8.73e-2)" "unprognostic (9.54e-2)" PPIA CYPA ENSG00000196262 "Peptidylprolyl isomerase A" P62937 7 44796680-44824564 "Enzymes, Essential proteins, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Host-virus interaction" "Isomerase, Rotamase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric progenitor cells: 3095.2;Megakaryocytes: 1360.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach)" "CAB004655, HPA058345" Uncertain "Secreted to blood" Enzyme NA NA 230000000 "Cluster 13: Non-specific - Mitochondria" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 67: Non-specific - Unknown function" "Cluster 15: Non-specific - Protein processing" 96 "CAB004655: , HPA058345: " "unprognostic (9.63e-3)" "unprognostic (6.63e-2)" "unprognostic (2.39e-2)" "unprognostic (2.22e-2)" "unprognostic (1.12e-1)" "unprognostic (2.42e-1)" "unprognostic (1.39e-3)" "unprognostic (1.19e-1)" "unprognostic (2.11e-3)" "unprognostic (8.90e-3)" "unprognostic (7.13e-2)" "potential prognostic unfavorable (4.53e-4)" "unprognostic (4.48e-2)" "validated prognostic unfavorable (1.91e-5)" "validated prognostic unfavorable (4.99e-9)" "potential prognostic unfavorable (8.07e-6)" "unprognostic (1.46e-2)" "unprognostic (4.63e-2)" "unprognostic (2.45e-1)" "unprognostic (1.80e-2)" "unprognostic (7.52e-2)" "potential prognostic unfavorable (6.29e-5)" "unprognostic (8.07e-2)" "unprognostic (1.41e-1)" "unprognostic (1.71e-1)" "unprognostic (5.77e-2)" "unprognostic (1.20e-1)" "unprognostic (4.13e-1)" "unprognostic (2.18e-1)" "unprognostic (6.18e-2)" "unprognostic (5.99e-2)" PPIAL4A "COAS2, PPIAL4, PPIAL4B" ENSG00000263353 "Peptidylprolyl isomerase A like 4A" Q9Y536 1 120889771-120890530 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" HPA058345 Uncertain NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 48: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" 2 "HPA058345: " PPIAL4C ENSG00000288867 "Peptidylprolyl isomerase A like 4C" A0A0B4J2A2 1 149583848-149584607 "Enzymes, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "intestine: 1.4;lymphoid tissue: 1.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" HPA058345 Uncertain NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" "HPA058345: " PPIAL4D ENSG00000289549 "Peptidylprolyl isomerase A like 4D" F5H284 1 145241415-145242174 "Enzymes, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA058345 Uncertain NA NA "HPA058345: " PPIAL4E ENSG00000271567 "Peptidylprolyl isomerase A like 4E" A0A075B759 1 144372875-144373634 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA058345 Uncertain NA NA "HPA058345: " PPIAL4F ENSG00000279782 "Peptidylprolyl isomerase A like 4F" P0DN26 1 144592893-144593652 "Enzymes, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA058345 Uncertain NA NA "HPA058345: " PPIAL4G ENSG00000236334 "Peptidylprolyl isomerase A like 4G" P0DN37 1 148482548-148483302 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "intestine: 1.6" "Cell type enhanced" "Detected in single" "Renal collecting duct principal cells: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" HPA058345 Uncertain NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 61: BICR 18 - Protein kinases" "Cluster 105: Non-specific - Mixed function" "HPA058345: " "unprognostic (3.11e-1)" "unprognostic (8.44e-3)" PPIAL4H ENSG00000270339 "Peptidylprolyl isomerase A like 4H" A0A075B767 1 146344006-146344765 "Enzymes, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA058345 Uncertain NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 15: Non-specific - Transcription" "Cluster 14: Myeloid leukemia - Innate immune response" "HPA058345: " PPIB "B, CYP-S1, CYPB, OI9, PPIase, SCYLP" ENSG00000166794 "Peptidylprolyl isomerase B" P23284 15 64155740-64163134 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Isomerase, Rotamase" "Disease variant, Dwarfism, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 1667.8;Extravillous trophoblasts: 2057.3;Plasma cells: 1608.1;Syncytiotrophoblasts: 1390.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011487, HPA012720" Enhanced Supported "Nucleoplasm,Endoplasmic reticulum" "Secreted to blood" Enzyme No No 27000000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 8: Non-specific - Secretory pathway" 45 "Endoplasmic reticulum" Nucleoplasm "CAB011487: , HPA012720: " "unprognostic (2.45e-1)" "unprognostic (1.05e-2)" "unprognostic (5.99e-2)" "unprognostic (7.70e-3)" "unprognostic (3.52e-1)" "unprognostic (1.06e-1)" "unprognostic (2.49e-2)" "unprognostic (1.31e-1)" "unprognostic (1.72e-3)" "unprognostic (2.48e-2)" "validated prognostic unfavorable (4.29e-4)" "validated prognostic unfavorable (8.14e-5)" "unprognostic (3.44e-2)" "unprognostic (1.13e-2)" "unprognostic (3.50e-3)" "unprognostic (3.82e-3)" "unprognostic (2.68e-2)" "unprognostic (7.14e-2)" "unprognostic (2.68e-3)" "unprognostic (3.92e-2)" "unprognostic (1.14e-1)" "unprognostic (1.59e-1)" "unprognostic (7.68e-2)" "unprognostic (1.26e-1)" "unprognostic (1.28e-1)" "unprognostic (5.93e-2)" "unprognostic (1.77e-2)" "unprognostic (1.32e-1)" "unprognostic (1.67e-1)" "unprognostic (1.62e-1)" "unprognostic (6.11e-3)" PPIC CYPC ENSG00000168938 "Peptidylprolyl isomerase C" P45877 5 123023250-123036725 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 361.0;Esophageal apical cells: 656.8;Esophageal suprabasal cells: 506.5;Hepatic stellate cells: 238.8" "Cell type enhanced" "Detected in many" "endothelial cell: 46.5;ependymal cell: 24.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Skin - Fibroblasts_1, Spleen - Fibroblasts_1, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039163 Approved "Intracellular and membrane" Enzyme NA NA 1100000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 15: Kidney cancer - Membrane components" "Cluster 108: Fibroblasts - ECM organization" 8 "HPA039163: " "unprognostic (4.40e-2)" "unprognostic (1.05e-1)" "unprognostic (1.38e-1)" "unprognostic (2.22e-1)" "unprognostic (1.43e-1)" "unprognostic (1.85e-1)" "unprognostic (1.56e-1)" "potential prognostic unfavorable (1.35e-4)" "unprognostic (8.71e-2)" "potential prognostic unfavorable (5.43e-4)" "unprognostic (2.46e-2)" "unprognostic (2.55e-3)" "unprognostic (1.41e-1)" "unprognostic (1.48e-2)" "unprognostic (7.18e-2)" "unprognostic (1.22e-3)" "unprognostic (1.56e-3)" "unprognostic (1.12e-1)" "unprognostic (1.68e-2)" "unprognostic (8.25e-2)" "unprognostic (4.91e-2)" "unprognostic (1.39e-1)" "unprognostic (1.03e-1)" "unprognostic (2.86e-1)" "unprognostic (6.64e-2)" "unprognostic (6.41e-3)" "unprognostic (1.70e-2)" "unprognostic (3.65e-2)" "unprognostic (2.03e-1)" "unprognostic (1.89e-2)" "unprognostic (2.20e-1)" PPID "CYP-40, CypD" ENSG00000171497 "Peptidylprolyl isomerase D" Q08752 4 158709127-158723396 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Protein transport, Transport" "Chaperone, Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019520, HPA019692" Approved Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Primary cilium,Cytosol" NA NA 4900 "Cluster 45: Eosinophils - Unknown function" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 21: Non-specific - Metabolism" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 17: Non-specific - RNA processing" 27 Cytosol "Nucleoplasm, Nucleoli, Nucleoli rim, Primary cilium" "HPA019520: , HPA019692: " "unprognostic (1.30e-2)" "unprognostic (1.01e-2)" "unprognostic (1.03e-1)" "unprognostic (2.47e-2)" "unprognostic (1.89e-1)" "unprognostic (8.09e-2)" "unprognostic (1.22e-2)" "unprognostic (9.39e-2)" "unprognostic (5.41e-3)" "unprognostic (2.43e-1)" "potential prognostic favorable (2.73e-4)" "unprognostic (3.57e-2)" "unprognostic (9.32e-2)" "unprognostic (2.13e-2)" "unprognostic (1.98e-1)" "unprognostic (4.26e-3)" "unprognostic (2.78e-1)" "unprognostic (4.08e-1)" "unprognostic (1.93e-1)" "unprognostic (1.34e-1)" "unprognostic (2.07e-1)" "unprognostic (4.02e-2)" "unprognostic (1.28e-2)" "unprognostic (4.90e-2)" "unprognostic (4.38e-3)" "unprognostic (1.85e-2)" "unprognostic (2.90e-2)" "unprognostic (2.56e-1)" "unprognostic (5.02e-1)" "unprognostic (5.04e-2)" "unprognostic (4.47e-3)" PPIE "CyP-33, MGC111222, MGC3736" ENSG00000084072 "Peptidylprolyl isomerase E" Q9UNP9 1 39692182-39763914 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Isomerase, RNA-binding, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019357, HPA020131" Approved Supported "Nuclear speckles" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 97: Non-specific - Cellular respiration" 54 "Nuclear speckles" "HPA019357: , HPA020131: " "unprognostic (1.42e-1)" "unprognostic (2.13e-1)" "unprognostic (1.56e-1)" "unprognostic (5.06e-3)" "unprognostic (1.18e-1)" "unprognostic (8.70e-2)" "unprognostic (1.90e-1)" "unprognostic (1.01e-1)" "unprognostic (6.64e-3)" "unprognostic (6.89e-3)" "potential prognostic favorable (1.94e-5)" "unprognostic (2.94e-2)" "unprognostic (6.11e-2)" "potential prognostic unfavorable (1.63e-4)" "unprognostic (8.43e-2)" "unprognostic (3.40e-1)" "unprognostic (3.88e-2)" "unprognostic (2.36e-1)" "unprognostic (1.67e-1)" "unprognostic (4.02e-1)" "unprognostic (2.67e-1)" "unprognostic (3.15e-2)" "unprognostic (1.29e-2)" "unprognostic (1.49e-1)" "unprognostic (1.62e-3)" "unprognostic (9.27e-2)" "unprognostic (2.93e-1)" "unprognostic (3.00e-2)" "unprognostic (6.76e-2)" "unprognostic (1.08e-1)" "unprognostic (2.91e-1)" PPIF "Cyp-D, CypD, hCyP3" ENSG00000108179 "Peptidylprolyl isomerase F" P30405 10 79347469-79355334 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Apoptosis, Necrosis" "Isomerase, Rotamase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "cDC: 178.0;Esophageal apical cells: 329.4;Megakaryocyte progenitors: 239.2;Megakaryocytes: 772.7;monocytes: 307.8;Neutrophils: 206.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 75.3" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 544.5" "Heart muscle - Cardiomyocytes, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077416 Supported Mitochondria NA NA 260000 "Cluster 21: Neutrophils - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 27: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 26 Mitochondria "HPA077416: " "unprognostic (2.25e-1)" "unprognostic (2.37e-1)" "unprognostic (2.91e-1)" "unprognostic (2.15e-1)" "unprognostic (2.53e-1)" "unprognostic (2.30e-1)" "unprognostic (3.64e-2)" "potential prognostic favorable (2.44e-4)" "unprognostic (3.54e-3)" "unprognostic (1.95e-2)" "unprognostic (2.57e-3)" "unprognostic (3.55e-3)" "unprognostic (8.79e-2)" "unprognostic (2.92e-1)" "unprognostic (3.26e-1)" "unprognostic (1.60e-2)" "unprognostic (5.31e-3)" "unprognostic (6.49e-2)" "unprognostic (3.22e-2)" "unprognostic (2.40e-1)" "unprognostic (1.61e-1)" "unprognostic (1.29e-1)" "unprognostic (6.42e-2)" "unprognostic (1.40e-3)" "unprognostic (1.78e-2)" "unprognostic (2.45e-1)" "unprognostic (2.63e-2)" "unprognostic (7.51e-2)" "unprognostic (1.33e-1)" "potential prognostic unfavorable (2.86e-4)" "unprognostic (4.23e-2)" PPIG "CARS-Cyp, SCAF10, SRCyp" ENSG00000138398 "Peptidylprolyl isomerase G" Q13427 2 169584342-169641406 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021788, HPA057469" Supported Supported "Nuclear speckles,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 16: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 35 "Nuclear speckles" Cytosol "HPA021788: , HPA057469: " "unprognostic (1.02e-1)" "unprognostic (2.40e-1)" "unprognostic (2.60e-1)" "unprognostic (1.88e-1)" "unprognostic (2.95e-1)" "unprognostic (7.88e-2)" "unprognostic (1.13e-1)" "unprognostic (2.50e-1)" "unprognostic (1.32e-1)" "unprognostic (3.24e-3)" "potential prognostic favorable (1.44e-5)" "unprognostic (1.75e-3)" "unprognostic (1.74e-2)" "potential prognostic unfavorable (5.63e-4)" "unprognostic (2.61e-1)" "unprognostic (9.73e-2)" "unprognostic (2.30e-2)" "unprognostic (2.90e-2)" "unprognostic (5.25e-3)" "unprognostic (2.61e-2)" "unprognostic (3.99e-2)" "unprognostic (1.62e-2)" "unprognostic (2.34e-3)" "unprognostic (1.04e-1)" "unprognostic (7.75e-2)" "unprognostic (6.40e-2)" "unprognostic (7.67e-3)" "unprognostic (3.92e-2)" "unprognostic (3.35e-1)" "unprognostic (2.40e-1)" "unprognostic (1.93e-1)" PPIH "CYP-20, CYPH, MGC5016, SnuCyp-20, USA-CYP" ENSG00000171960 "Peptidylprolyl isomerase H" O43447 1 42658335-42676758 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Chaperone, Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 144.7;Extravillous trophoblasts: 138.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059019 Approved NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 34: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 27: Non-specific - Cell proliferation" 42 "HPA059019: " "potential prognostic unfavorable (4.89e-4)" "unprognostic (5.86e-3)" "potential prognostic unfavorable (2.12e-4)" "unprognostic (5.54e-2)" "unprognostic (1.99e-1)" "unprognostic (1.52e-2)" "unprognostic (2.77e-1)" "unprognostic (1.09e-2)" "unprognostic (1.91e-2)" "unprognostic (1.63e-2)" "unprognostic (1.35e-2)" "unprognostic (4.25e-3)" "unprognostic (1.39e-2)" "validated prognostic unfavorable (3.14e-7)" "validated prognostic unfavorable (2.52e-4)" "unprognostic (5.28e-2)" "unprognostic (1.02e-2)" "unprognostic (2.13e-1)" "unprognostic (7.97e-2)" "unprognostic (3.18e-2)" "unprognostic (9.61e-2)" "unprognostic (7.31e-3)" "unprognostic (1.14e-1)" "unprognostic (7.84e-3)" "unprognostic (7.13e-3)" "unprognostic (9.09e-2)" "unprognostic (1.39e-1)" "unprognostic (3.66e-2)" "unprognostic (1.86e-1)" "unprognostic (1.48e-2)" "unprognostic (2.82e-1)" PPIL1 CYPL1 ENSG00000137168 "Peptidylprolyl isomerase like 1" Q9Y3C6 6 36854827-36874803 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Isomerase, Rotamase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 71.2;Differentiating spermatogonia: 68.8;Extravillous trophoblasts: 74.5;Migrating cytotrophoblasts: 81.9;Oocytes: 87.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062916 Supported Nucleoli NA NA 71000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 35: Non-specific - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 28: Non-specific - Nuclear processes" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 54 Nucleoli "HPA062916: " "unprognostic (1.36e-2)" "unprognostic (5.22e-3)" "unprognostic (1.44e-2)" "unprognostic (4.10e-2)" "unprognostic (4.05e-2)" "unprognostic (1.56e-1)" "unprognostic (1.32e-1)" "unprognostic (2.21e-1)" "unprognostic (1.36e-2)" "unprognostic (9.68e-2)" "potential prognostic favorable (5.03e-5)" "unprognostic (2.90e-2)" "unprognostic (4.74e-2)" "validated prognostic unfavorable (4.70e-8)" "validated prognostic unfavorable (6.14e-4)" "unprognostic (8.50e-3)" "unprognostic (1.98e-2)" "unprognostic (9.03e-2)" "unprognostic (3.76e-2)" "unprognostic (2.94e-3)" "unprognostic (3.45e-1)" "unprognostic (1.50e-2)" "unprognostic (4.00e-1)" "unprognostic (3.27e-2)" "unprognostic (2.86e-3)" "unprognostic (1.96e-1)" "unprognostic (7.07e-2)" "unprognostic (4.59e-2)" "unprognostic (1.94e-1)" "unprognostic (4.75e-2)" "unprognostic (4.80e-1)" PPIL2 "CYC4, Cyp-60, UBOX7" ENSG00000100023 "Peptidylprolyl isomerase like 2" Q13356 22 21666000-21700015 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035344, HPA055637" Supported Enhanced Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 66: Non-specific - Mitochondria" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 13 Nucleoplasm "HPA035344: , HPA055637: " "unprognostic (1.44e-1)" "unprognostic (1.77e-3)" "unprognostic (2.22e-1)" "unprognostic (3.17e-1)" "unprognostic (2.33e-2)" "unprognostic (1.98e-1)" "unprognostic (1.98e-1)" "unprognostic (9.42e-2)" "unprognostic (1.61e-1)" "unprognostic (1.05e-1)" "potential prognostic favorable (5.52e-7)" "unprognostic (4.32e-3)" "unprognostic (2.13e-1)" "unprognostic (1.47e-2)" "unprognostic (8.25e-2)" "unprognostic (3.44e-2)" "unprognostic (2.87e-2)" "unprognostic (1.38e-1)" "unprognostic (3.77e-2)" "unprognostic (1.55e-1)" "unprognostic (1.33e-1)" "unprognostic (9.58e-2)" "unprognostic (7.84e-3)" "unprognostic (1.27e-1)" "unprognostic (8.36e-3)" "unprognostic (1.64e-1)" "unprognostic (2.95e-2)" "unprognostic (1.37e-1)" "unprognostic (2.70e-1)" "unprognostic (2.22e-1)" "unprognostic (2.01e-1)" PPIL3 CyPJ ENSG00000240344 "Peptidylprolyl isomerase like 3" Q9H2H8 2 200870907-200889303 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing, mRNA splicing" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 140.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040765, HPA062187" Approved Approved Nucleoplasm,Nucleoli NA NA 110000 "Cluster 41: Basophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 2: Neurons - Nucleosome" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" 14 Nucleoplasm Nucleoli "HPA040765: , HPA062187: " "unprognostic (1.11e-1)" "unprognostic (1.67e-1)" "unprognostic (2.12e-1)" "unprognostic (8.06e-2)" "unprognostic (2.20e-1)" "unprognostic (1.65e-1)" "unprognostic (1.66e-1)" "unprognostic (2.17e-1)" "unprognostic (1.53e-1)" "unprognostic (4.64e-3)" "potential prognostic favorable (4.53e-4)" "unprognostic (8.18e-2)" "unprognostic (1.40e-1)" "unprognostic (2.28e-1)" "unprognostic (1.30e-1)" "unprognostic (2.07e-1)" "unprognostic (7.28e-2)" "unprognostic (3.73e-3)" "unprognostic (2.36e-1)" "unprognostic (2.88e-3)" "unprognostic (5.63e-2)" "unprognostic (2.06e-2)" "unprognostic (8.23e-2)" "unprognostic (1.65e-1)" "unprognostic (3.08e-2)" "unprognostic (2.30e-1)" "unprognostic (6.90e-2)" "unprognostic (2.43e-2)" "unprognostic (6.59e-2)" "unprognostic (5.59e-2)" "unprognostic (1.57e-1)" PPIL4 ENSG00000131013 "Peptidylprolyl isomerase like 4" Q8WUA2 6 149504495-149546043 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" "Isomerase, RNA-binding, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031599, HPA031600" Approved Enhanced Nucleoplasm,Cytosol NA NA 9000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 22: Epididymis - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 103: Non-specific - Basic cellular processes" 21 Nucleoplasm Cytosol "HPA031599: , HPA031600: " "unprognostic (6.54e-2)" "unprognostic (2.02e-2)" "potential prognostic unfavorable (5.50e-6)" "unprognostic (6.33e-2)" "unprognostic (1.53e-1)" "unprognostic (3.21e-1)" "unprognostic (8.66e-2)" "unprognostic (3.25e-2)" "unprognostic (4.00e-2)" "unprognostic (1.09e-2)" "potential prognostic favorable (3.41e-4)" "unprognostic (3.24e-2)" "unprognostic (6.72e-3)" "unprognostic (1.22e-3)" "unprognostic (1.94e-2)" "unprognostic (2.19e-1)" "unprognostic (1.43e-1)" "unprognostic (3.47e-1)" "unprognostic (2.02e-1)" "unprognostic (5.08e-3)" "potential prognostic unfavorable (3.19e-4)" "unprognostic (1.33e-1)" "unprognostic (2.23e-2)" "unprognostic (5.55e-2)" "unprognostic (3.63e-2)" "unprognostic (2.45e-2)" "unprognostic (6.45e-3)" "unprognostic (3.47e-1)" "unprognostic (5.36e-1)" "unprognostic (2.72e-1)" "unprognostic (2.08e-1)" PPIL6 "bA425D10.6, dJ919F19.1, MGC41939, RSPH12" ENSG00000185250 "Peptidylprolyl isomerase like 6" Q8IXY8 6 109390215-109441171 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 33.5;testis: 17.5" "Group enriched" "Detected in many" 4 "Choroid plexus epithelial cells: 204.4;Early spermatids: 344.1;Endometrial ciliated cells: 378.1;Ependymal cells: 368.7;Epididymal efferent duct ciliated cells: 394.1;Fallopian tube ciliated cells: 530.1;Late primary spermatocytes: 423.8;Respiratory ciliated cells: 525.4" "Group enriched" "Detected in all" 7 "choroid plexus epithelial cell: 153.8;ependymal cell: 421.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.5" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA036717, HPA058165" Approved Approved Nucleoli,Vesicles NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" 4 Vesicles Nucleoli "HPA036717: , HPA058165: " "unprognostic (5.92e-2)" "unprognostic (3.85e-2)" "unprognostic (1.95e-1)" "unprognostic (2.46e-2)" "unprognostic (1.41e-2)" "unprognostic (1.05e-1)" "unprognostic (1.17e-1)" "unprognostic (4.03e-3)" "unprognostic (2.54e-1)" "unprognostic (6.75e-3)" "unprognostic (1.08e-1)" "unprognostic (1.01e-2)" "unprognostic (8.23e-2)" "unprognostic (7.65e-2)" "unprognostic (1.40e-1)" "unprognostic (6.80e-2)" "unprognostic (1.97e-1)" "unprognostic (3.00e-2)" "unprognostic (2.47e-2)" "unprognostic (2.48e-1)" "unprognostic (1.22e-1)" "unprognostic (1.25e-2)" "unprognostic (2.45e-1)" "unprognostic (1.07e-1)" "unprognostic (9.50e-2)" "unprognostic (1.23e-2)" "unprognostic (1.40e-2)" "unprognostic (1.10e-1)" PPIP5K1 "HISPPD2A, IPS1, KIAA0377, VIP1" ENSG00000168781 "Diphosphoinositol pentakisphosphate kinase 1" Q6PFW1 15 43533462-43590208 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 65.3" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 68.8;Cone photoreceptor cells: 93.2;Rod photoreceptor cells: 99.8;Sertoli cells: 125.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039380 Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 35: Non-specific - DNA binding" "Cluster 58: Non-specific - Nuclear processes" "Cluster 79: Photoreceptor cells - Phototransduction" "Plasma membrane, Cytosol" "HPA039380: " "unprognostic (1.26e-1)" "unprognostic (4.40e-2)" "potential prognostic favorable (9.51e-4)" "unprognostic (1.93e-1)" "unprognostic (4.27e-1)" "unprognostic (4.37e-2)" "unprognostic (2.02e-1)" "unprognostic (4.74e-3)" "unprognostic (6.83e-3)" "unprognostic (2.94e-2)" "potential prognostic favorable (1.74e-4)" "unprognostic (2.41e-2)" "potential prognostic favorable (6.77e-5)" "unprognostic (1.41e-1)" "unprognostic (5.58e-2)" "unprognostic (8.51e-3)" "unprognostic (1.78e-1)" "unprognostic (2.49e-1)" "unprognostic (1.13e-1)" "unprognostic (2.78e-2)" "unprognostic (7.52e-2)" "unprognostic (2.19e-1)" "unprognostic (6.11e-3)" "unprognostic (4.86e-2)" "unprognostic (2.19e-2)" "unprognostic (1.95e-1)" "unprognostic (4.98e-3)" "unprognostic (9.50e-2)" "unprognostic (3.32e-1)" "unprognostic (6.03e-2)" "unprognostic (1.49e-1)" PPIP5K2 "CFAP160, DFNB100, HISPPD1, KIAA0433, VIP2" ENSG00000145725 "Diphosphoinositol pentakisphosphate kinase 2" O43314 5 103120149-103212799 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hearing "Kinase, Transferase" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 288.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037895, HPA038442" Approved Approved Vesicles NA NA "Cluster 41: Basophils - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 37: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 6 Vesicles "HPA037895: , HPA038442: " "unprognostic (6.94e-3)" "unprognostic (9.10e-2)" "unprognostic (3.52e-2)" "unprognostic (3.27e-1)" "unprognostic (2.76e-1)" "unprognostic (1.26e-1)" "unprognostic (1.15e-1)" "unprognostic (6.51e-2)" "unprognostic (4.45e-2)" "potential prognostic unfavorable (9.27e-6)" "potential prognostic favorable (6.91e-5)" "unprognostic (4.92e-2)" "unprognostic (1.52e-1)" "unprognostic (1.21e-1)" "unprognostic (1.94e-1)" "unprognostic (1.98e-1)" "unprognostic (1.81e-1)" "unprognostic (1.66e-2)" "unprognostic (1.05e-1)" "unprognostic (4.59e-3)" "potential prognostic unfavorable (6.52e-5)" "unprognostic (2.42e-1)" "unprognostic (1.69e-2)" "unprognostic (9.22e-2)" "unprognostic (2.05e-3)" "unprognostic (2.01e-1)" "unprognostic (2.73e-2)" "unprognostic (1.24e-1)" "unprognostic (2.95e-1)" "potential prognostic unfavorable (3.12e-4)" "unprognostic (1.73e-1)" PPL ENSG00000118898 Periplakin O60437 16 4882507-4960741 "Plasma proteins, Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 218.4;esophagus: 697.4;vagina: 274.1" "Cell type enriched" "Detected in many" 6 "Esophageal apical cells: 5894.4" "Cell type enhanced" "Detected in many" "ependymal cell: 33.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 108.1" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal cortex cells, Skeletal muscle - Macrophages, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA042550, HPA059859" Enhanced Uncertain "Nucleoplasm,Plasma membrane,Basal body,Cytosol" NA NA 190000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 65 "Plasma membrane, Basal body, Cytosol" Nucleoplasm "HPA042550: , HPA059859: " "unprognostic (4.79e-2)" "unprognostic (1.65e-1)" "unprognostic (1.87e-1)" "unprognostic (9.50e-2)" "unprognostic (8.80e-2)" "unprognostic (1.57e-1)" "unprognostic (2.69e-2)" "potential prognostic unfavorable (6.81e-6)" "unprognostic (2.31e-1)" "unprognostic (2.52e-1)" "unprognostic (6.71e-2)" "unprognostic (1.34e-1)" "unprognostic (2.08e-2)" "unprognostic (7.10e-3)" "unprognostic (1.29e-2)" "unprognostic (1.26e-1)" "unprognostic (4.43e-2)" "unprognostic (2.75e-1)" "unprognostic (8.09e-2)" "potential prognostic unfavorable (5.28e-4)" "unprognostic (6.62e-2)" "unprognostic (4.55e-2)" "unprognostic (1.97e-3)" "unprognostic (2.52e-1)" "unprognostic (1.08e-2)" "unprognostic (3.68e-1)" "unprognostic (1.22e-1)" "unprognostic (3.52e-2)" "unprognostic (7.69e-2)" "unprognostic (8.53e-2)" "unprognostic (6.58e-2)" PPM1A "MGC9201, PP2CA, PP2Calpha" ENSG00000100614 "Protein phosphatase, Mg2+/Mn2+ dependent 1A" P35813 14 60245752-60299087 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 134.9" "Cell type enhanced" "Detected in all" "Early spermatids: 533.5;Late spermatids: 999.2;Neutrophils: 413.6;Platelets: 410.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029209 Approved Supported "Plasma membrane,Cytosol" NA NA 900000 "Cluster 21: Neutrophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 29 Cytosol "Plasma membrane" "HPA029209: " "unprognostic (3.30e-2)" "unprognostic (1.59e-1)" "unprognostic (3.10e-2)" "unprognostic (7.69e-2)" "unprognostic (9.87e-2)" "unprognostic (1.83e-3)" "unprognostic (1.88e-1)" "unprognostic (1.73e-1)" "unprognostic (1.23e-1)" "potential prognostic unfavorable (6.39e-4)" "validated prognostic favorable (1.12e-9)" "validated prognostic favorable (1.66e-4)" "unprognostic (5.22e-2)" "unprognostic (7.80e-2)" "unprognostic (3.93e-2)" "unprognostic (2.46e-1)" "unprognostic (1.12e-1)" "unprognostic (1.49e-1)" "unprognostic (6.61e-2)" "unprognostic (2.27e-2)" "unprognostic (5.12e-3)" "unprognostic (5.80e-2)" "unprognostic (2.95e-1)" "unprognostic (9.87e-2)" "unprognostic (5.67e-2)" "unprognostic (1.65e-2)" "unprognostic (7.83e-2)" "unprognostic (4.56e-2)" "unprognostic (2.63e-1)" "unprognostic (1.73e-3)" "unprognostic (2.33e-1)" PPM1B "PP2CB, PP2CBETA, PPC2BETAX" ENSG00000138032 "Protein phosphatase, Mg2+/Mn2+ dependent 1B" O75688 2 44167969-44244384 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 136.7;Bergmann glia: 258.3;Brain excitatory neurons: 119.2;Brain inhibitory neurons: 118.1;Choroid plexus epithelial cells: 309.6;Distal convoluted tubule cells: 199.2;Loop of henle epithelial cells: 101.2;Microglia: 130.3;Oligodendrocyte progenitor cells: 196.7;Oligodendrocytes: 298.3;Other brain neurons: 91.6;Papillary tip epithelial cells: 87.5;Podocytes: 112.8;Proximal tubule cells: 102.3;Renal collecting duct intercalated cells: 129.2;Renal collecting duct principal cells: 95.7;Renal connecting tubule cells: 128.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016745 Approved Approved Nucleoli,Cytosol NA NA 77000 "Cluster 21: Neutrophils - Unknown function" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 102: Non-specific - Mixed function" 27 "Nucleoli, Cytosol" "HPA016745: " "potential prognostic favorable (5.57e-4)" "unprognostic (1.62e-1)" "unprognostic (3.60e-1)" "unprognostic (3.05e-1)" "unprognostic (1.07e-3)" "unprognostic (1.05e-1)" "unprognostic (1.22e-1)" "unprognostic (3.95e-2)" "unprognostic (2.85e-1)" "unprognostic (2.14e-1)" "potential prognostic favorable (1.96e-4)" "unprognostic (2.69e-2)" "unprognostic (8.82e-3)" "unprognostic (1.09e-1)" "unprognostic (1.38e-1)" "unprognostic (3.85e-2)" "unprognostic (1.21e-1)" "unprognostic (5.12e-2)" "unprognostic (1.51e-2)" "unprognostic (4.19e-2)" "unprognostic (1.35e-1)" "unprognostic (9.86e-2)" "unprognostic (1.07e-1)" "unprognostic (2.09e-1)" "unprognostic (3.26e-1)" "unprognostic (1.37e-1)" "unprognostic (7.25e-2)" "unprognostic (1.73e-1)" "unprognostic (1.81e-1)" "unprognostic (4.72e-2)" "unprognostic (2.48e-1)" PPM1D "PP2C-DELTA, Wip1" ENSG00000170836 "Protein phosphatase, Mg2+/Mn2+ dependent 1D" O15297 17 60600193-60666280 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Hydrolase, Protein phosphatase" "Autism spectrum disorder, Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022277, HPA061848" Approved Supported Nucleoplasm,Nucleoli NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 64: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 15 Nucleoplasm Nucleoli "HPA022277: , HPA061848: " "unprognostic (1.24e-3)" "unprognostic (1.11e-1)" "unprognostic (4.17e-1)" "unprognostic (2.87e-1)" "unprognostic (4.52e-2)" "unprognostic (2.95e-1)" "unprognostic (1.17e-1)" "unprognostic (6.68e-2)" "unprognostic (2.09e-2)" "unprognostic (6.56e-2)" "validated prognostic favorable (2.39e-5)" "validated prognostic favorable (5.04e-4)" "unprognostic (1.98e-1)" "unprognostic (4.22e-3)" "unprognostic (1.44e-2)" "unprognostic (1.95e-2)" "unprognostic (1.94e-1)" "unprognostic (1.61e-1)" "unprognostic (1.28e-3)" "unprognostic (3.84e-1)" "unprognostic (1.23e-1)" "potential prognostic favorable (4.88e-4)" "unprognostic (1.31e-1)" "potential prognostic unfavorable (2.20e-4)" "unprognostic (3.32e-1)" "unprognostic (2.53e-3)" "unprognostic (1.42e-2)" "unprognostic (6.82e-2)" "unprognostic (2.95e-1)" "unprognostic (9.09e-2)" "unprognostic (1.62e-1)" PPM1E "CaMKP-N, KIAA1072, POPX1, PP2CH" ENSG00000175175 "Protein phosphatase, Mg2+/Mn2+ dependent 1E" Q8WY54 17 58755854-58985179 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "adrenal gland: 5.1;brain: 11.7;retina: 20.7;testis: 6.2" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 361.2;Brain excitatory neurons: 657.4;Brain inhibitory neurons: 265.9;Cone photoreceptor cells: 1397.3;Early primary spermatocytes: 438.3;Early spermatids: 257.8;Ependymal cells: 268.3;Gonadotrophs: 366.7;Other brain neurons: 400.7;Retinal bipolar cells: 550.2;Retinal horizontal cells: 1254.1;Rod photoreceptor cells: 386.7" "Cell type enhanced" "Detected in all" "hippocampal CA4: 1649.8;hippocampal dentate gyrus: 2643.5" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 4.4;Prostate Adenocarcinoma (TCGA): 4.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 15.0;prostate cancer: 7.8" "Adrenal gland - Adrenal cortex cells, Colon - Colon enteroendocrine cells, Lung - Respiratory ciliated cells, Pancreas - Beta cells, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018462, HPA019263" Approved Approved Nucleoplasm,Nucleoli Yes No "Cluster 32: Basophils - Transcription" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 29: Forebrain - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 35: Neurons - Synaptic function & neurogenesis" 4 Nucleoli Nucleoplasm "HPA018462: , HPA019263: " "unprognostic (1.41e-1)" "unprognostic (3.48e-1)" "potential prognostic favorable (5.93e-6)" "unprognostic (2.38e-1)" "potential prognostic favorable (3.16e-5)" "unprognostic (1.43e-1)" "unprognostic (4.71e-2)" PPM1F "CAMKP, CaMKPase, FEM-2, KIAA0015, POPX2" ENSG00000100034 "Protein phosphatase, Mg2+/Mn2+ dependent 1F" P49593 22 21919425-21952848 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Apoptosis "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Lymphatic endothelial cells: 77.4;monocytes: 81.0;Neutrophils: 220.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 28.7" "Group enriched" "Detected in all" 7 "dendritic cells: 9.0;granulocytes: 28.7;monocytes: 24.6" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030989, HPA030990" Approved Approved "Nucleoplasm,Plasma membrane" NA NA 390000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 5: Spleen - Immune response" "Cluster 1: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 9 Nucleoplasm "Plasma membrane" "HPA030989: , HPA030990: " "unprognostic (1.18e-1)" "unprognostic (1.29e-1)" "unprognostic (3.59e-2)" "unprognostic (1.79e-3)" "unprognostic (2.68e-1)" "unprognostic (3.23e-1)" "unprognostic (7.31e-2)" "unprognostic (2.19e-2)" "unprognostic (9.96e-2)" "unprognostic (2.33e-1)" "potential prognostic favorable (1.25e-5)" "unprognostic (1.10e-3)" "unprognostic (5.84e-2)" "unprognostic (5.80e-3)" "unprognostic (1.90e-1)" "unprognostic (1.24e-1)" "unprognostic (2.04e-1)" "unprognostic (1.50e-1)" "unprognostic (4.26e-2)" "unprognostic (4.13e-2)" "unprognostic (2.68e-2)" "unprognostic (1.52e-1)" "unprognostic (1.15e-2)" "unprognostic (3.74e-2)" "unprognostic (1.68e-2)" "potential prognostic favorable (6.36e-4)" "unprognostic (4.05e-2)" "unprognostic (1.91e-2)" "unprognostic (1.15e-1)" "unprognostic (6.73e-2)" "unprognostic (4.63e-1)" PPM1G "PP2CG, PP2Cgamma" ENSG00000115241 "Protein phosphatase, Mg2+/Mn2+ dependent 1G" O15355 2 27381195-27409591 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 232.2" "Group enriched" "Detected in all" 6 "Early spermatids: 1469.0;Late primary spermatocytes: 1906.4;Late spermatids: 5463.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035530, HPA035531" Enhanced Enhanced Nucleoplasm NA NA 30000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 39: Testis - Nuclear processes" "Cluster 21: Non-specific - Metabolism" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 108 Nucleoplasm "HPA035530: , HPA035531: " "unprognostic (2.59e-1)" "unprognostic (1.32e-1)" "unprognostic (3.65e-2)" "unprognostic (2.76e-3)" "unprognostic (3.25e-1)" "unprognostic (1.84e-1)" "unprognostic (1.39e-1)" "unprognostic (3.73e-2)" "unprognostic (6.97e-2)" "unprognostic (1.84e-3)" "unprognostic (6.41e-3)" "unprognostic (2.33e-2)" "unprognostic (6.11e-2)" "validated prognostic unfavorable (2.30e-7)" "validated prognostic unfavorable (6.08e-9)" "potential prognostic unfavorable (8.34e-5)" "unprognostic (1.55e-2)" "unprognostic (2.24e-2)" "unprognostic (1.60e-1)" "unprognostic (8.99e-3)" "unprognostic (6.99e-3)" "unprognostic (1.16e-2)" "unprognostic (4.86e-1)" "unprognostic (3.43e-3)" "unprognostic (3.95e-1)" "unprognostic (1.01e-1)" "unprognostic (1.54e-1)" "unprognostic (5.21e-2)" "unprognostic (1.36e-1)" "unprognostic (3.27e-1)" "unprognostic (3.08e-1)" PPM1H "ARHCL1, FLJ13253, KIAA1157, NERPP-2C" ENSG00000111110 "Protein phosphatase, Mg2+/Mn2+ dependent 1H" Q9ULR3 12 62643994-62935150 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 34.8;parathyroid gland: 39.8" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 376.8;Endometrial glandular cells: 442.9;Hematopoietic stem cells: 341.6;Lacrimal acinar cells: 358.7;Oligodendrocytes: 443.8;Pituitary stem cells: 378.2;Prostatic glandular cells: 361.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.9" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Colon - Colon enteroendocrine cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Skin - Outer root sheath cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020694, HPA044244, HPA058777" Approved Supported Nucleoplasm NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 35: Non-specific - DNA binding" "Cluster 34: Testis cancer - Unknown function" "Cluster 51: Secretory epithelial cells - Mixed function" 11 Nucleoplasm "CAB020694: , HPA044244: , HPA058777: " "unprognostic (1.52e-1)" "unprognostic (2.01e-2)" "unprognostic (2.44e-2)" "unprognostic (1.79e-1)" "unprognostic (4.06e-1)" "unprognostic (2.80e-1)" "unprognostic (1.64e-1)" "unprognostic (3.95e-2)" "unprognostic (2.52e-1)" "unprognostic (4.50e-3)" "unprognostic (5.50e-2)" "unprognostic (1.40e-2)" "unprognostic (6.60e-2)" "unprognostic (4.90e-3)" "unprognostic (3.54e-2)" "unprognostic (3.22e-2)" "unprognostic (1.13e-2)" "unprognostic (3.06e-1)" "unprognostic (5.60e-3)" "unprognostic (8.99e-2)" "unprognostic (1.17e-1)" "unprognostic (4.22e-3)" "potential prognostic favorable (3.05e-4)" "unprognostic (2.59e-1)" "unprognostic (2.96e-1)" "unprognostic (6.72e-2)" "unprognostic (1.03e-1)" "unprognostic (6.22e-2)" "unprognostic (2.38e-1)" "unprognostic (2.52e-3)" "unprognostic (1.43e-2)" PPM1J "DKFZp434P1514, FLJ35951, MGC19531, PP2Czeta, PPP2CZ" ENSG00000155367 "Protein phosphatase, Mg2+/Mn2+ dependent 1J" Q5JR12 1 112709994-112715332 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 71.0;testis: 66.1" "Group enriched" "Detected in some" 6 "Early spermatids: 87.2;Late spermatids: 258.5" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 18.4;ependymal cell: 27.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "plasmacytoid DC: 74.5" "Lineage enriched" "Detected in many" 15 "dendritic cells: 74.5" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal medulla cells, Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Skin - Keratinocyte (other), Testis - Late spermatids" "Region enriched" "Detected in many" 7 "olfactory bulb: 27.3" "Low region specificity" "Detected in all" HPA046045 Uncertain Approved Vesicles NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 4 Vesicles "HPA046045: " "unprognostic (2.31e-1)" "unprognostic (1.74e-1)" "unprognostic (1.04e-1)" "unprognostic (2.45e-2)" "unprognostic (3.46e-2)" "unprognostic (9.89e-2)" "unprognostic (7.47e-3)" "unprognostic (2.29e-3)" "unprognostic (1.55e-2)" "unprognostic (2.24e-2)" "unprognostic (2.06e-1)" "unprognostic (1.14e-1)" "unprognostic (2.57e-1)" "unprognostic (3.77e-2)" "unprognostic (6.26e-3)" "unprognostic (1.30e-1)" "unprognostic (1.58e-1)" "unprognostic (3.96e-2)" "potential prognostic unfavorable (3.36e-4)" "unprognostic (7.18e-2)" "unprognostic (9.49e-2)" "unprognostic (4.50e-1)" "unprognostic (2.57e-2)" "unprognostic (1.93e-1)" "potential prognostic favorable (5.53e-4)" "unprognostic (2.46e-1)" "unprognostic (5.42e-2)" "unprognostic (1.40e-1)" PPM1K "BDP, DKFZp761G058, hPTMP, PP2Ckappa, PP2Cm" ENSG00000163644 "Protein phosphatase, Mg2+/Mn2+ dependent 1K" Q8N3J5 4 88257620-88284769 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 86.6" "Cell type enhanced" "Detected in many" "Breast lactating cells: 275.1;Cardiomyocytes: 289.5;pDCs: 249.4;Sertoli cells: 204.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "lymphoma: 40.9" "Heart muscle - Cardiomyocytes, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020066, HPA020862, HPA023891" Approved Supported Mitochondria No No "Cluster 14: Non-specific - Unknown function" "Cluster 35: Non-specific - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 55: Lymphoma - Immune response" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 8 Mitochondria "HPA020066: , HPA020862: , HPA023891: " "unprognostic (3.52e-3)" "unprognostic (1.80e-1)" "unprognostic (1.43e-1)" "unprognostic (2.14e-1)" "unprognostic (3.79e-2)" "unprognostic (9.18e-2)" "unprognostic (2.52e-1)" "unprognostic (2.17e-1)" "unprognostic (1.81e-2)" "unprognostic (4.70e-2)" "unprognostic (5.88e-3)" "unprognostic (1.87e-2)" "unprognostic (1.41e-1)" "unprognostic (2.16e-1)" "unprognostic (2.17e-1)" "unprognostic (1.74e-2)" "unprognostic (1.66e-1)" "unprognostic (2.58e-2)" "unprognostic (3.04e-2)" "unprognostic (3.79e-2)" "unprognostic (6.95e-2)" "unprognostic (4.87e-3)" "unprognostic (1.69e-2)" "unprognostic (3.25e-2)" "unprognostic (7.93e-2)" "unprognostic (9.86e-2)" "unprognostic (1.99e-1)" "unprognostic (2.18e-2)" "unprognostic (1.62e-1)" "unprognostic (8.41e-2)" "unprognostic (4.43e-1)" PPM1L PP2CE ENSG00000163590 "Protein phosphatase, Mg2+/Mn2+ dependent 1L" Q5SGD2 3 160755602-161078902 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Corticotrophs: 1704.7;Salivary ionocytes: 1276.0;Thymic myoid cells: 1312.0;Thyrotrophs: 851.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 20.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 4.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Pituitary gland - Corticotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019891, HPA019953" Approved Approved Nucleoplasm,Cytosol NA NA 18000 "Cluster 25: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 1 Cytosol Nucleoplasm "HPA019891: , HPA019953: " "potential prognostic favorable (1.18e-4)" "unprognostic (3.87e-3)" "unprognostic (1.03e-1)" "unprognostic (1.14e-1)" "unprognostic (2.29e-1)" "unprognostic (4.41e-2)" "unprognostic (6.49e-2)" "unprognostic (1.33e-3)" "unprognostic (7.78e-2)" "unprognostic (1.42e-1)" "validated prognostic favorable (7.70e-5)" "validated prognostic favorable (3.86e-4)" "unprognostic (2.16e-1)" "unprognostic (1.75e-1)" "unprognostic (3.87e-1)" "unprognostic (1.43e-1)" "unprognostic (2.48e-2)" "unprognostic (6.89e-3)" "unprognostic (2.39e-2)" "unprognostic (8.33e-2)" "unprognostic (1.31e-3)" "unprognostic (2.99e-2)" "unprognostic (1.95e-1)" "unprognostic (2.41e-1)" "unprognostic (2.93e-1)" "unprognostic (7.05e-3)" "unprognostic (9.59e-2)" "unprognostic (2.00e-1)" "unprognostic (1.20e-2)" "unprognostic (7.82e-2)" PPM1M "FLJ32332, PP2Ceta" ENSG00000164088 "Protein phosphatase, Mg2+/Mn2+ dependent 1M" Q96MI6 3 52245759-52250599 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 46.8;Kupffer cells: 34.8;Late spermatids: 30.1;monocytes: 29.5;Neutrophil progenitors: 41.5;Neutrophils: 57.2" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 24.6;leukocyte: 20.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Spleen - Neutrophils_2, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036905, HPA062291" Uncertain Approved "Nuclear bodies" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 7: Non-specific - Ribosome" "Cluster 59: Leukemia - T-cell receptor" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 1 "Nuclear bodies" "HPA036905: , HPA062291: " "unprognostic (2.94e-1)" "unprognostic (1.17e-1)" "unprognostic (1.03e-1)" "unprognostic (2.63e-3)" "unprognostic (1.18e-1)" "unprognostic (1.37e-1)" "unprognostic (1.44e-2)" "potential prognostic unfavorable (7.45e-5)" "unprognostic (2.68e-2)" "unprognostic (3.02e-1)" "unprognostic (2.91e-2)" "unprognostic (1.42e-1)" "unprognostic (1.33e-3)" "unprognostic (2.22e-3)" "unprognostic (1.91e-1)" "potential prognostic favorable (5.82e-4)" "unprognostic (1.23e-1)" "unprognostic (8.61e-2)" "unprognostic (1.93e-1)" "unprognostic (9.99e-3)" "unprognostic (2.14e-1)" "unprognostic (2.58e-1)" "unprognostic (2.99e-2)" "unprognostic (1.24e-1)" "unprognostic (1.13e-1)" "unprognostic (4.74e-2)" "unprognostic (3.97e-1)" "unprognostic (3.09e-1)" "unprognostic (2.39e-1)" "unprognostic (6.89e-2)" "unprognostic (2.33e-1)" PPM1N FLJ40125 ENSG00000213889 "Protein phosphatase, Mg2+/Mn2+ dependent 1N (putative)" Q8N819 19 45488777-45502513 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 8 "skeletal muscle: 167.1" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 72.3;Extravillous trophoblasts: 190.1;Hofbauer cells: 34.7;Neutrophils: 52.6;Rod photoreceptor cells: 51.1" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in all" 4 "Testicular Germ Cell Tumor (TCGA): 50.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 6 "non-classical monocyte: 137.2" "Lineage enriched" "Detected in all" 11 "monocytes: 137.2" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA043577 Supported Vesicles NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 9: Non-specific - Receptor signaling" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" Vesicles "HPA043577: " "unprognostic (1.95e-1)" "unprognostic (3.62e-2)" "unprognostic (2.29e-1)" "unprognostic (6.56e-3)" "unprognostic (9.70e-2)" "unprognostic (2.97e-2)" "unprognostic (2.20e-1)" "unprognostic (1.80e-1)" "unprognostic (5.08e-2)" "unprognostic (6.18e-3)" "potential prognostic unfavorable (4.63e-6)" "unprognostic (6.78e-2)" "potential prognostic unfavorable (8.38e-4)" "potential prognostic unfavorable (7.02e-4)" "unprognostic (3.44e-2)" "unprognostic (7.68e-2)" "unprognostic (2.77e-1)" "unprognostic (1.41e-2)" "unprognostic (9.56e-2)" "unprognostic (1.09e-2)" "unprognostic (1.56e-1)" "unprognostic (1.08e-2)" "unprognostic (2.03e-2)" "unprognostic (1.04e-1)" "unprognostic (1.25e-1)" "unprognostic (2.89e-1)" "unprognostic (3.34e-1)" "unprognostic (4.42e-2)" "unprognostic (2.81e-1)" "unprognostic (3.43e-1)" "unprognostic (3.29e-1)" PPME1 "ABDH19, PME-1" ENSG00000214517 "Protein phosphatase methylesterase 1" Q9Y570 11 74171267-74254703 "Enzymes, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004541, HPA043900, HPA064396" Uncertain Supported "Nucleoplasm,Nuclear bodies" NA NA 52000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 14: Neurons - Synaptic function" "Cluster 72: Neuronal - Signal transduction" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 38 Nucleoplasm "Nuclear bodies" "CAB004541: , HPA043900: , HPA064396: " "unprognostic (1.32e-1)" "unprognostic (1.21e-3)" "unprognostic (2.77e-1)" "unprognostic (9.08e-3)" "unprognostic (1.89e-1)" "unprognostic (1.66e-1)" "unprognostic (2.07e-1)" "unprognostic (2.17e-2)" "unprognostic (3.28e-2)" "unprognostic (3.15e-2)" "potential prognostic favorable (2.89e-5)" "unprognostic (4.17e-2)" "unprognostic (4.15e-1)" "unprognostic (1.55e-2)" "unprognostic (6.04e-3)" "unprognostic (4.20e-3)" "potential prognostic unfavorable (1.79e-4)" "unprognostic (9.24e-2)" "unprognostic (6.48e-2)" "unprognostic (3.41e-2)" "unprognostic (2.00e-2)" "unprognostic (1.34e-3)" "potential prognostic unfavorable (6.62e-5)" "unprognostic (6.93e-2)" "unprognostic (1.20e-1)" "unprognostic (7.68e-2)" "unprognostic (1.61e-1)" "unprognostic (5.71e-2)" "unprognostic (2.03e-1)" "unprognostic (2.43e-1)" "unprognostic (1.44e-1)" PPOX "PPO, VP" ENSG00000143224 "Protoporphyrinogen oxidase" P50336 1 161166056-161178013 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Heme biosynthesis, Porphyrin biosynthesis" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 77.9;Erythrocyte progenitors: 86.1;Fallopian tube ciliated cells: 92.4;Respiratory ciliated cells: 91.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030123 Uncertain Approved Vesicles,Mitochondria,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 47: Leukemia - Hemostasis" "Cluster 107: Ciliated cells - Cilia assembly & function" 27 Mitochondria "Vesicles, Cytosol" "HPA030123: " "unprognostic (1.60e-1)" "unprognostic (4.49e-1)" "unprognostic (1.20e-1)" "potential prognostic favorable (3.58e-4)" "unprognostic (6.91e-2)" "unprognostic (8.62e-2)" "unprognostic (1.91e-1)" "potential prognostic favorable (1.55e-4)" "unprognostic (1.06e-1)" "unprognostic (1.92e-1)" "unprognostic (3.30e-3)" "unprognostic (4.35e-2)" "unprognostic (1.93e-1)" "unprognostic (6.32e-3)" "unprognostic (3.84e-2)" "unprognostic (1.35e-2)" "unprognostic (3.31e-2)" "unprognostic (1.01e-1)" "unprognostic (2.62e-1)" "unprognostic (2.16e-2)" "unprognostic (6.43e-2)" "unprognostic (6.13e-3)" "unprognostic (2.49e-1)" "unprognostic (8.74e-2)" "unprognostic (2.78e-1)" "unprognostic (8.81e-2)" "unprognostic (7.19e-2)" "unprognostic (1.32e-1)" "unprognostic (2.78e-1)" "unprognostic (3.17e-2)" "unprognostic (4.92e-3)" PPP1CA "PP-1A, PP1A, PP1alpha, PPP1A" ENSG00000172531 "Protein phosphatase 1 catalytic subunit alpha" P62136 11 67398181-67421183 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Cell cycle, Cell division, Glycogen metabolism, Host-virus interaction" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 416.0;Esophageal apical cells: 821.4;Esophageal basal cells: 411.7;Esophageal suprabasal cells: 458.0;Extravillous trophoblasts: 647.2;Hofbauer cells: 400.6;Migrating cytotrophoblasts: 409.0;Syncytiotrophoblasts: 475.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004545, HPA046833" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol,Flagellar centriole,Mid piece,End piece" NA NA 2300000 "Cluster 25: Non-specific - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 293 "Nucleoplasm, Plasma membrane, Cytosol" "Flagellar centriole, Mid piece, End piece" "CAB004545: , HPA046833: " "unprognostic (1.45e-2)" "unprognostic (2.43e-1)" "unprognostic (4.63e-1)" "unprognostic (2.13e-1)" "unprognostic (1.40e-1)" "unprognostic (1.23e-1)" "unprognostic (4.12e-2)" "unprognostic (2.13e-1)" "unprognostic (1.23e-2)" "unprognostic (2.74e-2)" "unprognostic (6.45e-3)" "unprognostic (1.14e-1)" "unprognostic (9.57e-2)" "unprognostic (1.08e-3)" "potential prognostic unfavorable (7.76e-5)" "unprognostic (9.86e-3)" "potential prognostic unfavorable (1.11e-5)" "unprognostic (2.45e-1)" "unprognostic (7.50e-2)" "unprognostic (7.51e-2)" "unprognostic (1.91e-1)" "unprognostic (3.98e-3)" "unprognostic (2.54e-1)" "unprognostic (2.28e-1)" "unprognostic (1.82e-1)" "unprognostic (5.85e-2)" "unprognostic (1.81e-1)" "unprognostic (2.42e-1)" "unprognostic (4.10e-2)" "unprognostic (4.02e-3)" "unprognostic (1.72e-1)" PPP1CB "MP, PP-1B, PP1B, PP1beta, PP1c, PPP1beta" ENSG00000213639 "Protein phosphatase 1 catalytic subunit beta" P62140 2 28751640-28802940 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Carbohydrate metabolism, Cell cycle, Cell division, Glycogen metabolism" "Hydrolase, Protein phosphatase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hematopoietic stem cells: 504.6;Neutrophils: 973.8" "Cell type enhanced" "Detected in all" "vascular associated smooth muscle cell: 330.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065425, CAB069426" Supported Supported Nucleoplasm,Cytosol NA NA 2100000 "Cluster 40: Monocytes - Innate immune response" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 72: Neuronal - Signal transduction" "Cluster 103: Non-specific - Basic cellular processes" 135 Nucleoplasm Cytosol "CAB069426: , HPA065425: " "unprognostic (1.27e-1)" "unprognostic (4.40e-2)" "unprognostic (2.91e-1)" "unprognostic (2.22e-1)" "unprognostic (3.96e-2)" "unprognostic (1.88e-2)" "unprognostic (8.50e-2)" "unprognostic (2.04e-2)" "unprognostic (9.49e-2)" "unprognostic (4.38e-2)" "potential prognostic favorable (5.40e-8)" "unprognostic (2.12e-2)" "unprognostic (4.17e-3)" "potential prognostic unfavorable (2.23e-6)" "unprognostic (1.36e-2)" "unprognostic (5.81e-2)" "unprognostic (5.56e-2)" "unprognostic (6.11e-2)" "unprognostic (1.61e-1)" "unprognostic (3.85e-2)" "unprognostic (8.22e-3)" "unprognostic (1.23e-3)" "unprognostic (1.28e-2)" "unprognostic (3.21e-1)" "unprognostic (3.30e-1)" "unprognostic (9.22e-2)" "unprognostic (1.73e-1)" "unprognostic (3.57e-1)" "unprognostic (4.42e-1)" "unprognostic (2.22e-2)" "unprognostic (3.78e-1)" PPP1CC "PP1C, PP1gamma" ENSG00000186298 "Protein phosphatase 1 catalytic subunit gamma" P36873 12 110719680-110742939 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Carbohydrate metabolism, Cell cycle, Cell division, Glycogen metabolism" "Hydrolase, Protein phosphatase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 574.2;Late primary spermatocytes: 843.3;Late spermatids: 1272.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022645, CAB079921" Uncertain Supported Nucleoplasm,Vesicles,Cytosol NA NA 2200000 "Cluster 7: Non-specific - Innate immune response" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 222 Cytosol "Nucleoplasm, Vesicles" "CAB022645: , CAB079921: " "unprognostic (6.70e-2)" "unprognostic (4.53e-1)" "unprognostic (3.93e-2)" "unprognostic (6.59e-2)" "unprognostic (1.02e-1)" "unprognostic (2.88e-1)" "unprognostic (4.47e-2)" "unprognostic (1.20e-2)" "unprognostic (6.70e-2)" "unprognostic (3.03e-3)" "potential prognostic favorable (2.76e-5)" "unprognostic (5.56e-2)" "unprognostic (2.15e-1)" "validated prognostic unfavorable (5.40e-7)" "validated prognostic unfavorable (5.30e-7)" "unprognostic (4.00e-3)" "unprognostic (2.18e-3)" "unprognostic (6.08e-2)" "unprognostic (5.86e-2)" "unprognostic (2.29e-1)" "unprognostic (3.63e-3)" "unprognostic (8.27e-2)" "unprognostic (8.25e-2)" "unprognostic (3.45e-2)" "unprognostic (8.78e-3)" "unprognostic (6.32e-2)" "unprognostic (5.27e-2)" "unprognostic (1.45e-1)" "unprognostic (2.28e-1)" "unprognostic (1.21e-2)" "unprognostic (2.46e-1)" PPP1R10 "CAT53, FB19, p99, PNUTS" ENSG00000204569 "Protein phosphatase 1 regulatory subunit 10" Q96QC0 6 30600413-30618612 "Essential proteins, Predicted intracellular proteins" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Epididymal basal cells: 148.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 7.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025501, HPA047248, HPA056756" Enhanced Enhanced "Nucleoplasm,Nuclear bodies" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 70: Non-specific - Protein processing" "Cluster 45: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 20: Non-specific - Transcription regulation" 27 Nucleoplasm "Nuclear bodies" "CAB025501: , HPA047248: , HPA056756: " "unprognostic (8.60e-2)" "unprognostic (3.45e-1)" "unprognostic (1.94e-1)" "unprognostic (9.61e-2)" "unprognostic (5.64e-2)" "unprognostic (1.36e-1)" "unprognostic (2.26e-1)" "unprognostic (1.17e-2)" "unprognostic (9.45e-3)" "unprognostic (9.17e-2)" "potential prognostic favorable (2.75e-12)" "unprognostic (1.32e-1)" "unprognostic (4.89e-2)" "unprognostic (2.85e-2)" "unprognostic (3.42e-2)" "unprognostic (1.18e-2)" "unprognostic (3.32e-2)" "unprognostic (2.75e-2)" "unprognostic (4.68e-2)" "unprognostic (8.92e-2)" "unprognostic (8.69e-2)" "unprognostic (8.65e-3)" "unprognostic (2.08e-1)" "unprognostic (6.19e-2)" "unprognostic (3.56e-2)" "unprognostic (1.60e-1)" "unprognostic (2.37e-3)" "unprognostic (2.34e-2)" "unprognostic (5.75e-2)" "unprognostic (7.60e-2)" "unprognostic (2.39e-2)" PPP1R11 "CFAP255, HCG-V, HCGV, TCTE5, Tctex5" ENSG00000204619 "Protein phosphatase 1 regulatory inhibitor subunit 11" O60927 6 30066709-30070333 "Enzymes, Essential proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Protein phosphatase inhibitor, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 8 "Late spermatids: 888.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043266, HPA060174" Approved Approved Vesicles NA NA 12000 "Cluster 21: Neutrophils - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 53: Neurons - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 21 Vesicles "HPA043266: , HPA060174: " "unprognostic (5.35e-3)" "unprognostic (9.26e-2)" "unprognostic (1.48e-2)" "unprognostic (6.28e-2)" "unprognostic (1.37e-2)" "unprognostic (4.98e-1)" "unprognostic (1.99e-1)" "unprognostic (4.32e-2)" "unprognostic (2.02e-1)" "unprognostic (1.76e-1)" "potential prognostic favorable (1.33e-4)" "unprognostic (2.36e-2)" "unprognostic (4.41e-2)" "unprognostic (6.85e-2)" "unprognostic (6.39e-2)" "unprognostic (1.49e-1)" "unprognostic (8.74e-2)" "unprognostic (1.35e-1)" "unprognostic (5.28e-2)" "unprognostic (2.66e-3)" "unprognostic (1.01e-1)" "unprognostic (3.13e-1)" "unprognostic (4.54e-2)" "unprognostic (4.75e-2)" "unprognostic (1.39e-1)" "unprognostic (2.28e-2)" "unprognostic (3.95e-2)" "unprognostic (1.03e-1)" "unprognostic (1.48e-1)" "unprognostic (4.43e-1)" PPP1R12A "M130, MBS, MYPT1" ENSG00000058272 "Protein phosphatase 1 regulatory subunit 12A" O14974 12 79773563-79935460 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 1425.0;Neutrophils: 2038.0;Smooth muscle cells: 1027.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Fibroblasts, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041296, HPA071956" Approved Supported "Nucleoli,Plasma membrane,Actin filaments,Cytosol" NA NA 210000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 34: Non-specific - Mixed function" "Cluster 61: BICR 18 - Protein kinases" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 58 "Actin filaments, Cytosol" "Nucleoli, Plasma membrane" "HPA041296: , HPA071956: " "unprognostic (3.78e-2)" "unprognostic (2.46e-1)" "unprognostic (3.78e-1)" "unprognostic (1.94e-2)" "unprognostic (3.04e-1)" "unprognostic (1.32e-2)" "unprognostic (3.24e-2)" "potential prognostic favorable (7.42e-4)" "unprognostic (1.05e-1)" "unprognostic (2.12e-3)" "validated prognostic favorable (2.26e-4)" "validated prognostic favorable (1.94e-4)" "unprognostic (9.95e-2)" "unprognostic (1.15e-3)" "unprognostic (7.50e-2)" "unprognostic (7.63e-3)" "unprognostic (4.82e-3)" "unprognostic (9.01e-3)" "unprognostic (2.08e-1)" "unprognostic (7.34e-2)" "potential prognostic unfavorable (1.38e-5)" "unprognostic (4.15e-3)" "unprognostic (6.92e-3)" "unprognostic (3.78e-1)" "unprognostic (2.29e-1)" "unprognostic (5.03e-3)" "unprognostic (5.81e-2)" "unprognostic (1.42e-1)" "unprognostic (2.25e-1)" "unprognostic (5.86e-2)" "unprognostic (2.38e-1)" PPP1R12B "MGC131980, MGC87886, MYPT2, PP1bp55" ENSG00000077157 "Protein phosphatase 1 regulatory subunit 12B" O60237 1 202348699-202592706 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 334.5" "Cell type enhanced" "Detected in many" "Adipocytes: 756.5;Cardiomyocytes: 2070.1;Ependymal cells: 985.5;Myonuclei: 1549.6" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Stomach Adenocarcinoma (TCGA): 52.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 16.0" "Lineage enriched" "Detected in many" 7 "granulocytes: 16.0" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Breast - Breast myoepithelial cells, Heart muscle - Cardiomyocytes, Kidney - Fibroblasts, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024171, HPA024640" Enhanced Approved "Plasma membrane,Actin filaments" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 30: White matter - Myelination" "Cluster 5: Rhabdoid - Unknown function" "Cluster 62: Smooth muscle cells - Muscle contraction" 7 "Plasma membrane, Actin filaments" "HPA024171: , HPA024640: " "unprognostic (2.21e-3)" "unprognostic (1.64e-1)" "unprognostic (3.16e-2)" "unprognostic (6.59e-2)" "unprognostic (9.63e-3)" "unprognostic (9.14e-2)" "unprognostic (4.27e-1)" "unprognostic (2.16e-1)" "unprognostic (3.73e-3)" "unprognostic (1.60e-2)" "validated prognostic favorable (1.76e-6)" "validated prognostic favorable (9.56e-6)" "unprognostic (3.03e-2)" "unprognostic (3.82e-2)" "unprognostic (9.66e-2)" "unprognostic (2.99e-2)" "unprognostic (2.69e-1)" "unprognostic (6.00e-2)" "unprognostic (1.53e-1)" "unprognostic (1.33e-2)" "unprognostic (4.35e-2)" "unprognostic (1.17e-1)" "unprognostic (2.10e-1)" "unprognostic (8.36e-2)" "unprognostic (3.23e-2)" "unprognostic (2.29e-2)" "unprognostic (8.13e-2)" "potential prognostic unfavorable (6.99e-4)" "unprognostic (1.72e-1)" "unprognostic (3.31e-2)" "unprognostic (3.90e-1)" PPP1R12C "AAVS1, DKFZP434D0412, LENG3, MBS85, p84, p85" ENSG00000125503 "Protein phosphatase 1 regulatory subunit 12C" Q9BZL4 19 55090914-55117637 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Vascular smooth muscle cells: 89.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043532 Approved NA NA 11000 "Cluster 25: Non-specific - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 62: Smooth muscle cells - Muscle contraction" 24 "HPA043532: " "unprognostic (2.62e-3)" "unprognostic (1.33e-1)" "unprognostic (3.16e-2)" "unprognostic (2.32e-1)" "unprognostic (1.94e-1)" "unprognostic (5.87e-3)" "unprognostic (1.07e-1)" "unprognostic (1.38e-1)" "unprognostic (9.78e-2)" "unprognostic (9.12e-2)" "unprognostic (9.71e-2)" "unprognostic (8.07e-2)" "unprognostic (2.77e-3)" "potential prognostic unfavorable (1.30e-4)" "unprognostic (1.13e-1)" "unprognostic (3.98e-2)" "unprognostic (3.80e-1)" "unprognostic (3.65e-1)" "unprognostic (4.10e-2)" "unprognostic (1.43e-1)" "unprognostic (1.99e-2)" "potential prognostic favorable (4.50e-5)" "unprognostic (1.11e-1)" "unprognostic (1.42e-1)" "unprognostic (1.54e-1)" "unprognostic (3.84e-3)" "unprognostic (8.00e-2)" "unprognostic (2.23e-1)" "unprognostic (2.94e-1)" "unprognostic (3.96e-1)" "unprognostic (1.42e-1)" PPP1R13B "ASPP1, KIAA0771, p53BP2-like, p85" ENSG00000088808 "Protein phosphatase 1 regulatory subunit 13B" Q96KQ4 14 103733195-103847575 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Heart muscle - Cardiomyocytes, Prostate - Prostate glandular cells, Spleen - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006394, CAB015454" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 35: Non-specific - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 77 Nucleoplasm Cytosol "CAB015454: , HPA006394: " "unprognostic (1.32e-1)" "unprognostic (2.80e-1)" "unprognostic (2.04e-1)" "unprognostic (2.65e-1)" "unprognostic (5.17e-2)" "unprognostic (1.74e-3)" "unprognostic (2.16e-1)" "unprognostic (2.06e-2)" "unprognostic (1.39e-1)" "unprognostic (9.80e-3)" "validated prognostic favorable (6.38e-8)" "validated prognostic favorable (9.68e-6)" "unprognostic (3.79e-2)" "unprognostic (3.38e-2)" "unprognostic (5.17e-2)" "potential prognostic favorable (1.22e-5)" "unprognostic (2.19e-1)" "unprognostic (4.22e-1)" "unprognostic (6.22e-3)" "unprognostic (3.40e-1)" "unprognostic (2.01e-1)" "unprognostic (9.98e-2)" "unprognostic (7.19e-2)" "unprognostic (2.21e-2)" "unprognostic (7.54e-2)" "unprognostic (4.28e-3)" "unprognostic (5.50e-2)" "unprognostic (2.18e-1)" "unprognostic (1.68e-1)" "unprognostic (7.68e-2)" "unprognostic (3.34e-3)" PPP1R13L "IASPP, RAI" ENSG00000104881 "Protein phosphatase 1 regulatory subunit 13 like" Q8WUF5 19 45379638-45406349 "Predicted intracellular proteins, Transcription factors" "Apoptosis, Transcription, Transcription regulation" Repressor "Cardiomyopathy, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 157.3;heart muscle: 124.0;skin 1: 187.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 259.4;Cytotrophoblasts: 153.5;Esophageal apical cells: 469.9;Esophageal suprabasal cells: 230.9;Granulosa cells: 158.1;Ocular epithelial cells: 190.1;Prostatic hillock cells: 155.7;Suprabasal keratinocytes: 164.5;Syncytiotrophoblasts: 247.5;Urothelial cells: 159.8" "Cell type enhanced" "Detected in many" "endothelial cell: 34.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Pituitary gland - Gonadotropes, Skin - Keratinocyte (other)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB005016, HPA041231, HPA059883" Approved Supported Cytosol NA Yes "Cluster 58: Skin - Keratinization" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 44 Cytosol "CAB005016: , HPA041231: , HPA059883: " "unprognostic (2.77e-1)" "unprognostic (4.36e-2)" "unprognostic (3.10e-1)" "unprognostic (2.63e-1)" "unprognostic (7.21e-2)" "unprognostic (3.77e-1)" "unprognostic (3.65e-1)" "unprognostic (9.41e-2)" "unprognostic (1.48e-2)" "unprognostic (3.34e-1)" "potential prognostic favorable (6.91e-4)" "unprognostic (1.11e-1)" "unprognostic (4.88e-2)" "potential prognostic unfavorable (1.75e-4)" "unprognostic (2.59e-2)" "potential prognostic unfavorable (2.03e-4)" "unprognostic (1.09e-2)" "unprognostic (1.55e-1)" "unprognostic (1.54e-3)" "unprognostic (4.92e-3)" "unprognostic (1.67e-1)" "unprognostic (3.37e-3)" "unprognostic (2.56e-3)" "unprognostic (3.71e-1)" "unprognostic (5.18e-1)" "unprognostic (7.03e-2)" "unprognostic (4.00e-2)" "unprognostic (4.30e-1)" "unprognostic (3.87e-2)" "unprognostic (2.39e-1)" "unprognostic (6.16e-2)" PPP1R14A "CPI-17, PPP1INL" ENSG00000167641 "Protein phosphatase 1 regulatory inhibitor subunit 14A" Q96A00 19 38251237-38256532 "Plasma proteins, Predicted intracellular proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 1609.9;brain: 860.8" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 558.0;Decidual stromal cells: 649.1;Granulosa cells: 265.2;Hepatic stellate cells: 994.0;Leydig cells: 257.1;Megakaryocytes: 1156.0;Oligodendrocytes: 432.7;Ovarian stromal cells: 325.2;Pericytes: 490.8;Peritubular myoid cells: 596.2;Smooth muscle cells: 956.9;Vascular smooth muscle cells: 1020.9" "Cell type enhanced" "Detected in all" "oligodendrocyte: 601.6;vascular associated smooth muscle cell: 285.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "memory B-cell: 300.8;naive B-cell: 285.6;plasmacytoid DC: 247.5" "Group enriched" "Detected in many" 24 "B-cells: 300.8;dendritic cells: 247.5" "Cancer enhanced" "Detected in many" "Rhabdoid: 99.5" "Kidney - Fibroblasts, Lung - Smooth muscle cells, Minor Salivary Gland - Smooth muscle cells, Pituitary gland - Fibroblasts, Prostate - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Spleen - Fibroblasts_1, Spleen - Fibroblasts_2, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005044, CAB009803, HPA042097, HPA054534" Enhanced Supported "Nucleoplasm,Nuclear bodies" NA NA 380000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 74: Non-specific - Signal transduction" "Cluster 11: White matter - Signal transduction" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 7 Nucleoplasm "Nuclear bodies" "CAB005044: , CAB009803: , HPA042097: , HPA054534: " "unprognostic (7.26e-2)" "unprognostic (1.30e-2)" "unprognostic (7.60e-2)" "unprognostic (4.88e-3)" "unprognostic (7.63e-2)" "unprognostic (1.03e-2)" "unprognostic (1.76e-1)" "unprognostic (2.65e-1)" "unprognostic (2.44e-2)" "unprognostic (2.15e-1)" "unprognostic (8.90e-2)" "potential prognostic favorable (5.16e-4)" "potential prognostic unfavorable (9.52e-4)" "unprognostic (2.83e-3)" "unprognostic (8.60e-3)" "unprognostic (1.17e-1)" "unprognostic (2.80e-1)" "unprognostic (3.74e-2)" "unprognostic (8.50e-3)" "unprognostic (2.35e-1)" "unprognostic (8.67e-2)" "unprognostic (2.44e-1)" "unprognostic (8.96e-3)" "unprognostic (5.93e-2)" "unprognostic (7.62e-2)" "unprognostic (4.84e-2)" "unprognostic (1.64e-1)" "unprognostic (2.44e-3)" "unprognostic (3.74e-1)" "unprognostic (3.47e-2)" "unprognostic (2.84e-1)" PPP1R14B "PHI-1, PLCB3N, PNG, SOM172" ENSG00000173457 "Protein phosphatase 1 regulatory inhibitor subunit 14B" Q96C90 11 64244479-64246943 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 624.5;pDCs: 873.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 75 "plasmacytoid DC: 383.3" "Lineage enriched" "Detected in all" 75 "dendritic cells: 383.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053882 Approved NA NA 55000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 24: Non-specific - Transcription" "Cluster 12: Non-specific - Vasculature" "Cluster 24: Non-specific - Unknown function" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 5 "HPA053882: " "unprognostic (4.43e-2)" "unprognostic (3.84e-1)" "unprognostic (1.79e-2)" "unprognostic (1.04e-3)" "unprognostic (1.88e-2)" "unprognostic (3.47e-1)" "unprognostic (7.94e-2)" "unprognostic (7.41e-2)" "unprognostic (1.61e-3)" "unprognostic (2.79e-2)" "validated prognostic unfavorable (4.33e-8)" "validated prognostic unfavorable (3.43e-7)" "unprognostic (1.96e-1)" "validated prognostic unfavorable (1.19e-7)" "validated prognostic unfavorable (2.23e-4)" "validated prognostic unfavorable (8.01e-4)" "validated prognostic unfavorable (1.13e-4)" "unprognostic (1.61e-1)" "unprognostic (1.84e-1)" "unprognostic (1.79e-2)" "unprognostic (3.59e-2)" "potential prognostic unfavorable (2.59e-4)" "unprognostic (1.67e-2)" "unprognostic (3.83e-2)" "unprognostic (9.88e-2)" "unprognostic (1.42e-1)" "unprognostic (8.76e-2)" "unprognostic (7.07e-2)" "unprognostic (3.08e-1)" "unprognostic (9.04e-2)" "unprognostic (1.75e-1)" PPP1R14C "CPI17-like, KEPI, NY-BR-81" ENSG00000198729 "Protein phosphatase 1 regulatory inhibitor subunit 14C" Q8TAE6 6 150143044-150250392 "Predicted intracellular proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 70.7;skeletal muscle: 62.3;skin 1: 90.3;thyroid gland: 55.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 109.5;Basal keratinocytes: 369.8;Cardiomyocytes: 140.3;Ependymal cells: 173.1;Fallopian tube ciliated cells: 110.6;Myosatellite cells: 112.0;Ocular epithelial cells: 368.3;Respiratory ciliated cells: 236.1;Sertoli cells: 109.8;Suprabasal keratinocytes: 350.1" "Cell type enhanced" "Detected in many" "ependymal cell: 184.5;midbrain-derived inhibitory: 153.7" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 77.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 35.8" "Colon - Colon enterocytes, Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2, Pancreas - Alpha cells, Pancreas - Beta cells, Skeletal muscle - Skeletal myocytes, Skin - Keratinocyte (other), Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB044667, HPA047907" Approved NA NA "Cluster 58: Skin - Keratinization" "Cluster 24: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" "CAB044667: , HPA047907: " "unprognostic (1.70e-3)" "unprognostic (1.37e-2)" "unprognostic (2.26e-1)" "unprognostic (2.88e-2)" "unprognostic (6.04e-3)" "unprognostic (3.11e-2)" "unprognostic (6.17e-2)" "unprognostic (5.62e-1)" "unprognostic (1.22e-2)" "unprognostic (2.66e-1)" "unprognostic (1.10e-1)" "unprognostic (8.49e-2)" "unprognostic (1.53e-1)" "unprognostic (2.39e-1)" "unprognostic (2.83e-2)" "unprognostic (1.08e-1)" "unprognostic (8.84e-2)" "unprognostic (8.91e-2)" "unprognostic (7.52e-2)" "unprognostic (7.96e-2)" "unprognostic (5.40e-3)" "potential prognostic favorable (9.64e-4)" "unprognostic (2.12e-2)" "unprognostic (2.63e-1)" "unprognostic (1.93e-1)" "unprognostic (8.98e-2)" "unprognostic (2.50e-2)" "unprognostic (1.36e-1)" PPP1R14D "CPI17-like, FLJ20251, GBPI-1, MGC119014, MGC119016" ENSG00000166143 "Protein phosphatase 1 regulatory inhibitor subunit 14D" Q9NXH3 15 40815451-40828709 "Predicted intracellular proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "intestine: 104.5" "Cell type enhanced" "Detected in some" "Colonocytes: 288.3;Enteric stem cells: 71.6;Enteric transient amplifying cells: 104.3;Enterocytes: 377.5;Gastric progenitor cells: 39.7;Goblet cells: 47.8;Neuroendocrine cells: 46.5;Paneth cells: 61.9;Tuft cells: 34.6" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 84.4;Rectum Adenocarcinoma (TCGA): 90.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "colorectal cancer: 30.6" "Breast - Breast glandular cells, Colon - Colon enterocytes, Kidney - Proximal tubular cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA041846 Uncertain NA NA "Cluster 77: Intestine - Digestion" "Cluster 25: Non-specific - Transcription" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" "HPA041846: " "unprognostic (4.56e-2)" "unprognostic (3.72e-3)" "unprognostic (1.14e-2)" "unprognostic (4.13e-3)" "unprognostic (1.10e-1)" "unprognostic (8.33e-3)" "unprognostic (8.79e-3)" "unprognostic (1.88e-2)" "unprognostic (3.31e-1)" "unprognostic (2.38e-2)" "unprognostic (9.72e-3)" "unprognostic (1.27e-1)" "potential prognostic unfavorable (1.05e-4)" "unprognostic (3.16e-1)" "unprognostic (2.39e-1)" "unprognostic (2.64e-1)" "unprognostic (4.35e-3)" "unprognostic (2.56e-1)" "unprognostic (3.12e-2)" "unprognostic (2.87e-2)" "unprognostic (2.17e-2)" "unprognostic (2.86e-1)" "unprognostic (1.82e-2)" "unprognostic (6.94e-3)" "unprognostic (4.44e-2)" PPP1R15A GADD34 ENSG00000087074 "Protein phosphatase 1 regulatory subunit 15A" O75807 19 48872212-48876059 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, Stress response, Translation regulation" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 529.2" "Cell type enhanced" "Detected in all" "Endometrial glandular cells: 1034.2;Endometrial luminal cells: 1140.2;Endometrial secretory cells: 921.4;Epididymal basal cells: 1707.9;Neutrophils: 1636.9" "Cell type enhanced" "Detected in all" "endothelial cell: 67.7;vascular associated smooth muscle cell: 55.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 335.1" "Group enriched" "Detected in all" 5 "dendritic cells: 114.2;granulocytes: 335.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018395, HPA020240" Approved Uncertain Vesicles NA NA "Cluster 41: Basophils - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 13: Non-specific - Mixed function" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 22 Vesicles "CAB018395: , HPA020240: " "unprognostic (4.66e-3)" "unprognostic (7.08e-2)" "unprognostic (3.42e-3)" "unprognostic (1.07e-3)" "unprognostic (1.46e-1)" "unprognostic (6.09e-2)" "unprognostic (2.47e-2)" "unprognostic (1.73e-2)" "unprognostic (8.84e-2)" "unprognostic (2.36e-1)" "unprognostic (6.22e-2)" "unprognostic (1.22e-2)" "unprognostic (5.77e-3)" "potential prognostic unfavorable (1.53e-4)" "unprognostic (9.01e-2)" "unprognostic (8.61e-2)" "unprognostic (2.35e-1)" "unprognostic (4.03e-2)" "unprognostic (2.59e-2)" "unprognostic (2.36e-2)" "unprognostic (4.31e-1)" "unprognostic (1.74e-2)" "unprognostic (1.63e-3)" "unprognostic (2.53e-1)" "unprognostic (8.07e-2)" "unprognostic (3.10e-3)" "unprognostic (1.43e-1)" "unprognostic (1.89e-2)" "unprognostic (1.64e-1)" "unprognostic (1.42e-2)" "unprognostic (9.35e-2)" PPP1R15B FLJ14744 ENSG00000158615 "Protein phosphatase 1 regulatory subunit 15B" Q5SWA1 1 204396492-204411887 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Translation regulation" "Diabetes mellitus, Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 110.6" "Cell type enhanced" "Detected in many" "monocytes: 255.9;Neutrophils: 420.6;Urothelial cells: 217.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061088 Approved "Golgi apparatus" No No "Cluster 28: Neutrophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 14 "Golgi apparatus" "HPA061088: " "unprognostic (8.24e-2)" "unprognostic (4.26e-2)" "unprognostic (1.01e-1)" "unprognostic (1.36e-2)" "unprognostic (1.48e-1)" "unprognostic (2.86e-1)" "unprognostic (2.67e-1)" "unprognostic (4.11e-2)" "unprognostic (1.85e-1)" "unprognostic (5.01e-3)" "potential prognostic favorable (3.03e-6)" "unprognostic (5.58e-2)" "unprognostic (1.29e-2)" "unprognostic (1.69e-1)" "unprognostic (4.43e-1)" "unprognostic (8.94e-3)" "unprognostic (4.32e-2)" "unprognostic (1.44e-1)" "unprognostic (2.26e-2)" "unprognostic (2.90e-1)" "unprognostic (4.40e-2)" "unprognostic (5.25e-2)" "unprognostic (9.60e-2)" "unprognostic (4.28e-2)" "unprognostic (1.50e-1)" "unprognostic (3.56e-1)" "unprognostic (2.34e-2)" "unprognostic (1.30e-1)" "unprognostic (2.47e-1)" "unprognostic (3.57e-3)" "unprognostic (2.70e-1)" PPP1R16A "MGC14333, MYPT3" ENSG00000160972 "Protein phosphatase 1 regulatory subunit 16A" Q96I34 8 144477969-144502121 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 263.1;Cholangiocytes: 178.7;Enterocytes: 392.5;Hepatocytes: 239.1;Parietal cells: 233.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells" "Low region specificity" "Detected in all" HPA023755 Uncertain Approved "Plasma membrane" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 40: Non-specific - Unknown function" "Cluster 1: Enterocytes - Absorption and Digestion" 42 "Plasma membrane" "HPA023755: " "unprognostic (7.76e-3)" "unprognostic (2.40e-2)" "unprognostic (2.62e-1)" "potential prognostic unfavorable (9.72e-4)" "unprognostic (1.91e-1)" "unprognostic (6.84e-2)" "unprognostic (3.00e-2)" "unprognostic (7.71e-2)" "unprognostic (5.23e-2)" "unprognostic (1.11e-2)" "unprognostic (2.05e-1)" "unprognostic (9.59e-2)" "unprognostic (3.81e-2)" "unprognostic (1.02e-3)" "unprognostic (8.54e-2)" "unprognostic (1.96e-1)" "unprognostic (5.64e-2)" "unprognostic (2.91e-2)" "unprognostic (1.37e-1)" "unprognostic (2.07e-1)" "unprognostic (5.52e-3)" "unprognostic (1.11e-2)" "unprognostic (3.68e-3)" "unprognostic (2.40e-2)" "unprognostic (3.48e-2)" "unprognostic (1.80e-1)" "unprognostic (4.33e-2)" "unprognostic (1.78e-2)" "unprognostic (1.14e-1)" "unprognostic (1.53e-1)" "unprognostic (5.28e-2)" PPP1R16B "ANKRD4, KIAA0823, TIMAP" ENSG00000101445 "Protein phosphatase 1 regulatory subunit 16B" Q96T49 20 38805697-38923024 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 73.0;lymphoid tissue: 39.3" "Cell type enhanced" "Detected in many" "B-cells: 365.8;Brain inhibitory neurons: 162.4;Innate lymphoid cells: 368.0;Lymphatic endothelial cells: 166.8;NK-cells: 516.2;Oligodendrocytes: 421.9;pDCs: 409.8;Proximal tubule cells: 305.6;Retinal horizontal cells: 296.5;T-cells: 569.7;Thymocytes: 448.0;Vascular endothelial cells: 162.1" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 626.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 17 "Leukemia: 18.2;lymphoma: 46.7;Myeloma: 27.4;Neuroblastoma: 15.9" "Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Prostate - Endothelial cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049571, HPA079512" Approved Supported "Nuclear speckles,Plasma membrane" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 43 "Plasma membrane" "Nuclear speckles" "HPA049571: , HPA079512: " "unprognostic (6.37e-2)" "unprognostic (2.27e-2)" "unprognostic (2.04e-2)" "unprognostic (1.44e-2)" "unprognostic (1.46e-2)" "unprognostic (1.38e-1)" "unprognostic (3.18e-1)" "unprognostic (6.40e-2)" "potential prognostic favorable (1.40e-4)" "unprognostic (6.68e-2)" "validated prognostic favorable (2.70e-7)" "validated prognostic favorable (2.46e-4)" "unprognostic (3.78e-1)" "unprognostic (2.25e-1)" "potential prognostic favorable (3.61e-4)" "unprognostic (5.25e-3)" "unprognostic (1.30e-1)" "unprognostic (2.53e-1)" "unprognostic (2.92e-1)" "unprognostic (2.58e-2)" "unprognostic (1.81e-1)" "unprognostic (7.38e-3)" "unprognostic (9.14e-2)" "unprognostic (3.19e-1)" "unprognostic (5.56e-2)" "unprognostic (4.42e-2)" "unprognostic (1.01e-1)" "unprognostic (1.66e-1)" "unprognostic (4.59e-2)" "unprognostic (3.40e-1)" "unprognostic (8.35e-2)" PPP1R17 "C7orf16, GSBS" ENSG00000106341 "Protein phosphatase 1 regulatory subunit 17" O96001 7 31687215-31708455 "Human disease related genes, Predicted intracellular proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 21.6" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 48.5;Early spermatids: 64.2;Late spermatids: 178.6" "Group enriched" "Detected in many" 5 "Bergmann glia: 9.9;thalamic excitatory: 26.1" "Group enriched" "Detected in some" 4 "Glioblastoma Multiforme (TCGA): 1.0;Testicular Germ Cell Tumor (TCGA): 1.1" "Group enriched" "Detected in many" 4 "amygdala: 18.6;cerebellum: 40.5;hypothalamus: 18.3;midbrain: 21.3;thalamus: 34.9" "Immune cell enriched" "Detected in some" 4 "non-classical monocyte: 52.2" "Lineage enriched" "Detected in many" 21 "monocytes: 52.2" "Cancer enhanced" "Detected in some" "Bone cancer: 4.9;lung cancer: 9.5" "Adrenal gland - Adrenal medulla cells, Testis - Late spermatids" "Region enriched" "Detected in many" 32 "cerebellum: 430.8" "HPA047819, HPA073123" Enhanced NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 27: Cerebellum - Synaptic function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" "HPA047819: , HPA073123: " "unprognostic (1.19e-1)" "unprognostic (2.84e-2)" "unprognostic (2.65e-1)" "unprognostic (1.98e-1)" PPP1R18 "KIAA1949, phostensin" ENSG00000146112 "Protein phosphatase 1 regulatory subunit 18" Q6NYC8 6 30676389-30687895 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Microglia: 43.3;Oligodendrocyte progenitor cells: 17.7" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 50.8;leukocyte: 71.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "eosinophil: 216.0;neutrophil: 170.0" "Lineage enriched" "Detected in all" 5 "granulocytes: 216.0" "Low cancer specificity" "Detected in all" "Pituitary gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044745, HPA051000" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 5800 "Cluster 45: Eosinophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 6: Leukemia - Signal transduction" "Cluster 102: Non-specific - Mixed function" 83 "Plasma membrane" Nucleoplasm "HPA044745: , HPA051000: " "unprognostic (2.33e-1)" "unprognostic (4.01e-2)" "unprognostic (2.31e-3)" "unprognostic (4.06e-3)" "unprognostic (1.42e-1)" "unprognostic (8.97e-2)" "unprognostic (1.17e-1)" "unprognostic (2.00e-1)" "unprognostic (1.09e-1)" "unprognostic (3.67e-2)" "unprognostic (1.17e-1)" "potential prognostic unfavorable (8.64e-7)" "unprognostic (7.17e-2)" "unprognostic (1.30e-1)" "unprognostic (4.72e-3)" "unprognostic (1.17e-1)" "potential prognostic unfavorable (6.12e-4)" "unprognostic (5.89e-2)" "unprognostic (2.19e-1)" "unprognostic (8.66e-2)" "unprognostic (6.16e-3)" "unprognostic (1.47e-1)" "unprognostic (6.41e-3)" "unprognostic (6.25e-2)" "unprognostic (2.70e-1)" "unprognostic (2.29e-1)" "unprognostic (8.97e-2)" "unprognostic (7.65e-2)" "unprognostic (3.24e-1)" PPP1R1A ENSG00000135447 "Protein phosphatase 1 regulatory inhibitor subunit 1A" Q13522 12 54575387-54588659 "Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 779.6;tongue: 253.3" "Group enriched" "Detected in many" 4 "Granulosa cells: 74.6;Hepatocytes: 258.6;Pancreatic islet cells: 210.4" "Cell type enhanced" "Detected in many" "hippocampal dentate gyrus: 58.5;medium spiny neuron: 34.8" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 66.9;Liver Hepatocellular Carcinoma (TCGA): 55.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 14 "Bone cancer: 57.7" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Minor Salivary Gland - Adipocytes (Minor salivary gland), Pancreas - Beta cells, Skin - Adipocytes (Skin)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007811, HPA041542" Approved NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 33: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 4 "CAB007811: , HPA041542: " "unprognostic (6.81e-2)" "unprognostic (3.30e-2)" "unprognostic (2.92e-2)" "unprognostic (2.17e-1)" "potential prognostic favorable (9.26e-4)" "unprognostic (1.10e-1)" "unprognostic (9.22e-2)" "validated prognostic unfavorable (4.30e-8)" "validated prognostic unfavorable (3.26e-4)" "unprognostic (1.46e-2)" "unprognostic (9.06e-3)" "unprognostic (4.75e-3)" "unprognostic (2.81e-1)" "unprognostic (2.30e-1)" "unprognostic (1.99e-3)" "unprognostic (5.63e-2)" "unprognostic (9.74e-3)" "unprognostic (1.59e-1)" "unprognostic (4.26e-3)" "unprognostic (1.49e-1)" "unprognostic (1.02e-3)" "unprognostic (5.71e-3)" PPP1R1B "DARPP-32, FLJ20940" ENSG00000131771 "Protein phosphatase 1 regulatory inhibitor subunit 1B" Q9UD71 17 39626740-39636626 "Predicted intracellular proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 1368.7;choroid plexus: 1463.9" "Cell type enhanced" "Detected in many" "Bergmann glia: 131.2;Breast secretory cells: 153.2;Choroid plexus epithelial cells: 181.4;Colonocytes: 220.7;Enteric stem cells: 458.0;Enteric transient amplifying cells: 351.5;Gastric progenitor cells: 226.9;Goblet cells: 206.9;Lacrimal acinar cells: 239.1;Pancreatic duct cells: 192.2;Paneth cells: 259.1;Prostatic club cells: 451.0;Prostatic hillock cells: 194.0;Salivary acinar cells: 175.4;Tuft cells: 149.9" "Group enriched" "Detected in all" 5 "astrocyte: 59.8;Bergmann glia: 163.4;choroid plexus epithelial cell: 220.2;eccentric medium spiny neuron: 84.3;ependymal cell: 67.8;medium spiny neuron: 205.3" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 384.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 11 "eosinophil: 1.0" "Lineage enriched" "Detected in single" 11 "granulocytes: 1.0" "Group enriched" "Detected in many" 7 "Bile duct cancer: 113.4;breast cancer: 171.4;colorectal cancer: 185.6;Gastric cancer: 127.2;prostate cancer: 56.6" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal medulla cells, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Skin - Eccrine sweat gland cells" "Region enriched" "Detected in all" 8 "basal ganglia: 1244.1" "Region enriched" "Detected in all" 25 "basal ganglia: 2060.7" "CAB004026, HPA048630, HPA061142" Approved Approved NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 33: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 2 "CAB004026: , HPA048630: , HPA061142: " "unprognostic (1.57e-1)" "unprognostic (2.50e-1)" "unprognostic (3.67e-1)" "unprognostic (4.07e-2)" "unprognostic (2.74e-2)" "unprognostic (1.54e-1)" "unprognostic (1.38e-1)" "unprognostic (1.66e-1)" "unprognostic (1.43e-2)" "unprognostic (1.32e-2)" "unprognostic (3.38e-2)" "unprognostic (1.29e-2)" "unprognostic (1.61e-1)" "unprognostic (5.47e-2)" "unprognostic (5.75e-2)" "unprognostic (1.49e-1)" "potential prognostic favorable (2.02e-5)" "unprognostic (7.68e-2)" "unprognostic (1.25e-1)" "unprognostic (2.75e-2)" "potential prognostic favorable (4.59e-4)" "unprognostic (1.68e-1)" "unprognostic (1.85e-1)" "unprognostic (2.09e-2)" "unprognostic (1.32e-1)" "unprognostic (3.49e-2)" "unprognostic (1.73e-2)" "unprognostic (1.78e-2)" "unprognostic (2.34e-3)" PPP1R1C Inhibitor-1-like ENSG00000150722 "Protein phosphatase 1 regulatory inhibitor subunit 1C" Q8WVI7 2 181954241-182131398 "Predicted intracellular proteins" "Cell cycle, Cell division" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "heart muscle: 22.3" "Group enriched" "Detected in many" 4 "Cardiomyocytes: 303.8;Choroid plexus epithelial cells: 139.0;Early spermatids: 128.5;Gonadotrophs: 171.2;Late primary spermatocytes: 412.0;Late spermatids: 340.1;Myonuclei: 191.7;Retinal ganglion cells: 224.0" "Cell type enriched" "Detected in many" 4 "choroid plexus epithelial cell: 140.3" "Cancer enriched" "Detected in single" 19 "Glioblastoma Multiforme (TCGA): 4.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Sarcoma: 11.3;thyroid cancer: 13.2" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Pituitary gland - Gonadotropes, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Skin - Outer root sheath cells, Stomach - Gastric mucous cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA055043 Approved "Nucleoplasm,Nucleoli,Golgi apparatus" NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 5: Rhabdoid - Unknown function" "Cluster 55: Myocytes - Oxidative muscle function" 1 Nucleoplasm "Nucleoli, Golgi apparatus" "HPA055043: " "unprognostic (1.32e-1)" "unprognostic (1.41e-1)" "unprognostic (1.04e-2)" "unprognostic (8.23e-2)" "unprognostic (1.10e-1)" "potential prognostic unfavorable (8.77e-4)" PPP1R2 "IPP2, PPP1R2A" ENSG00000184203 "Protein phosphatase 1 regulatory inhibitor subunit 2" P41236 3 195514428-195543386 "Essential proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 505.1;Late primary spermatocytes: 466.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Inner root sheath cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "HPA043729, HPA059420" Approved Nucleoplasm,Cytosol NA NA 33000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 63: Non-specific - Protein processing" "Cluster 9: T-cells - Adaptive immunity: Regulation" 19 Nucleoplasm Cytosol "HPA043729: , HPA059420: " "unprognostic (2.12e-2)" "unprognostic (1.45e-1)" "unprognostic (2.63e-1)" "unprognostic (2.32e-1)" "unprognostic (2.09e-1)" "unprognostic (5.15e-2)" "unprognostic (3.69e-1)" "unprognostic (3.13e-1)" "unprognostic (3.89e-1)" "unprognostic (2.10e-1)" "potential prognostic favorable (1.70e-7)" "unprognostic (1.30e-3)" "unprognostic (1.38e-1)" "unprognostic (6.36e-2)" "unprognostic (9.02e-2)" "unprognostic (1.11e-2)" "unprognostic (1.89e-1)" "unprognostic (1.84e-1)" "unprognostic (1.78e-1)" "unprognostic (1.75e-2)" "unprognostic (2.81e-3)" "unprognostic (5.25e-2)" "unprognostic (2.60e-2)" "unprognostic (1.01e-1)" "unprognostic (2.49e-1)" "unprognostic (2.29e-1)" "unprognostic (9.65e-3)" "unprognostic (1.64e-1)" "unprognostic (9.35e-2)" "unprognostic (3.11e-1)" "unprognostic (1.37e-1)" PPP1R21 "CCDC128, FLJ16566, KLRAQ1" ENSG00000162869 "Protein phosphatase 1 regulatory subunit 21" Q6ZMI0 2 48440598-48515391 "Disease related genes, Human disease related genes, Predicted intracellular proteins" RNA-binding "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 301.2;Oligodendrocytes: 288.5;Proximal tubule cells: 358.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036791, HPA036792" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 72: Kidney - Transmembrane transport" "Cluster 11: White matter - Signal transduction" "Cluster 59: Leukemia - T-cell receptor" "Cluster 7: Non-specific - Transcription" 22 Vesicles Nucleoplasm "HPA036791: , HPA036792: " "unprognostic (2.50e-1)" "unprognostic (1.24e-1)" "unprognostic (4.67e-1)" "unprognostic (2.33e-1)" "unprognostic (9.46e-3)" "unprognostic (1.60e-1)" "unprognostic (3.39e-2)" "unprognostic (1.11e-1)" "unprognostic (5.67e-2)" "potential prognostic favorable (1.16e-9)" "unprognostic (1.06e-2)" "unprognostic (5.22e-2)" "unprognostic (1.31e-2)" "unprognostic (3.66e-2)" "unprognostic (2.37e-1)" "unprognostic (2.91e-1)" "unprognostic (4.73e-2)" "unprognostic (2.72e-2)" "unprognostic (1.31e-1)" "unprognostic (3.34e-2)" "unprognostic (1.32e-2)" "unprognostic (8.40e-2)" "unprognostic (2.67e-1)" "unprognostic (7.58e-2)" "unprognostic (1.31e-1)" "unprognostic (5.28e-2)" "unprognostic (4.21e-1)" "unprognostic (3.69e-2)" "unprognostic (4.11e-1)" PPP1R26 KIAA0649 ENSG00000196422 "Protein phosphatase 1 regulatory subunit 26" Q5T8A7 9 135479079-135488893 "Predicted intracellular proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044686, HPA063817" Uncertain Enhanced Nucleoplasm NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 60: Stomach - Digestion" "Cluster 51: Neurons - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 9 Nucleoplasm "HPA044686: , HPA063817: " "unprognostic (1.30e-1)" "unprognostic (1.07e-1)" "unprognostic (2.24e-2)" "unprognostic (3.45e-2)" "unprognostic (2.09e-2)" "unprognostic (2.82e-1)" "unprognostic (1.69e-2)" "unprognostic (8.46e-2)" "unprognostic (2.86e-3)" "potential prognostic favorable (1.24e-6)" "unprognostic (1.31e-3)" "potential prognostic favorable (2.28e-4)" "unprognostic (4.27e-2)" "unprognostic (1.44e-1)" "unprognostic (1.02e-1)" "unprognostic (2.69e-2)" "unprognostic (2.41e-1)" "unprognostic (2.03e-1)" "unprognostic (2.02e-1)" "unprognostic (8.99e-3)" "unprognostic (1.98e-1)" "unprognostic (6.81e-2)" "unprognostic (1.37e-3)" "unprognostic (1.53e-1)" "unprognostic (1.93e-1)" "unprognostic (7.59e-3)" "unprognostic (1.94e-1)" "unprognostic (1.87e-1)" "unprognostic (3.60e-2)" PPP1R27 "DYSFIP1, toonin" ENSG00000182676 "Protein phosphatase 1 regulatory subunit 27" Q86WC6 17 81833492-81835050 "Predicted intracellular proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 26 "skeletal muscle: 1144.3" "Group enriched" "Detected in some" 5 "Early spermatids: 5.4;Gonadotrophs: 3.6;Late primary spermatocytes: 9.9;Myonuclei: 5.2;Thymic myoid cells: 10.9" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 11 "Head and Neck Squamous Cell Carcinoma (TCGA): 4.8" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 218 "Leukemia: 66.4" "Pituitary gland - Gonadotropes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA042227, HPA048632" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 16: Non-specific - Transcription" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 10 "Plasma membrane, Cytosol" "HPA042227: , HPA048632: " "unprognostic (2.51e-2)" PPP1R2B "MGC87149, PPP1R2P3" ENSG00000231989 "PPP1R2 family member B" Q6NXS1 5 156850295-156852528 "Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 136 "testis: 20.5" "Group enriched" "Detected in some" 16 "Early spermatids: 282.0;Late primary spermatocytes: 515.8;Late spermatids: 456.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "HPA043729, HPA059420" Approved Nucleoplasm,Cytosol NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 20: Myeloma - Immune response" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 4 Nucleoplasm Cytosol "HPA043729: , HPA059420: " "potential prognostic unfavorable (4.14e-4)" PPP1R2C "I-4, PPP1R2P9" ENSG00000102055 "PPP1R2C family member C" O14990 X 42777366-42778163 "Predicted intracellular proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 209 "testis: 76.2" "Group enriched" "Detected in some" 10 "Early spermatids: 825.6;Late primary spermatocytes: 344.2;Late spermatids: 658.0" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 24 "Testicular Germ Cell Tumor (TCGA): 2.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 3 "unprognostic (5.74e-2)" PPP1R32 "C11orf66, FLJ32771, IIIG9" ENSG00000162148 "Protein phosphatase 1 regulatory subunit 32" Q7Z5V6 11 61481120-61490931 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 50.5;testis: 90.6" "Group enriched" "Detected in many" 4 "Early spermatids: 273.1;Late spermatids: 625.9" "Cell type enriched" "Detected in all" 10 "ependymal cell: 103.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Lung - Respiratory ciliated cells, Pituitary gland - Gonadotropes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" HPA039068 Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol,Mid piece,Principal piece,End piece" NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 3 "Plasma membrane" "Nucleoplasm, Cytosol, Mid piece, Principal piece, End piece" "HPA039068: " "unprognostic (2.10e-1)" "unprognostic (9.22e-2)" "unprognostic (6.24e-2)" "unprognostic (1.28e-2)" "unprognostic (1.10e-1)" "unprognostic (8.69e-2)" "unprognostic (4.21e-2)" "unprognostic (9.61e-2)" "unprognostic (1.07e-1)" "potential prognostic unfavorable (1.25e-8)" "unprognostic (1.90e-2)" "unprognostic (2.32e-1)" "potential prognostic favorable (1.42e-4)" "unprognostic (2.72e-2)" "unprognostic (1.49e-1)" "unprognostic (2.40e-1)" "unprognostic (1.65e-1)" "unprognostic (8.50e-2)" "unprognostic (2.11e-2)" "unprognostic (3.92e-2)" "unprognostic (8.23e-3)" "unprognostic (3.50e-2)" "unprognostic (3.26e-2)" "unprognostic (9.71e-2)" "unprognostic (4.05e-2)" "unprognostic (2.19e-1)" "unprognostic (4.95e-1)" "unprognostic (5.35e-2)" "unprognostic (2.42e-1)" PPP1R35 "C7orf47, MGC22793" ENSG00000160813 "Protein phosphatase 1 regulatory subunit 35" Q8TAP8 7 100435282-100436497 "Predicted intracellular proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 50.6" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 120.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021604, HPA051607" Approved Approved Nucleoplasm NA NA "Cluster 41: Basophils - Unknown function" "Cluster 67: Testis - Mixed function" "Cluster 25: Non-specific - Transcription" "Cluster 39: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" Nucleoplasm "HPA021604: , HPA051607: " "unprognostic (1.92e-2)" "unprognostic (2.44e-2)" "unprognostic (9.30e-3)" "unprognostic (6.51e-2)" "unprognostic (3.98e-2)" "unprognostic (1.09e-2)" "unprognostic (2.48e-1)" "unprognostic (7.06e-2)" "unprognostic (1.89e-1)" "potential prognostic unfavorable (3.43e-6)" "unprognostic (5.58e-3)" "unprognostic (5.90e-2)" "unprognostic (3.52e-2)" "unprognostic (1.46e-1)" "unprognostic (4.12e-2)" "unprognostic (1.28e-1)" "unprognostic (1.79e-1)" "unprognostic (1.17e-1)" "unprognostic (1.62e-2)" "unprognostic (6.32e-2)" "unprognostic (1.16e-2)" "unprognostic (6.88e-2)" "unprognostic (2.91e-1)" "unprognostic (3.94e-2)" "unprognostic (2.43e-2)" "unprognostic (1.74e-1)" "unprognostic (1.50e-1)" "unprognostic (1.52e-1)" "unprognostic (2.37e-1)" PPP1R36 C14orf50 ENSG00000165807 "Protein phosphatase 1 regulatory subunit 36" Q96LQ0 14 64549920-64589381 "Predicted intracellular proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 11.8;testis: 34.7" "Group enriched" "Detected in many" 5 "Early spermatids: 322.3;Late primary spermatocytes: 389.9;Late spermatids: 1275.4" "Cell type enhanced" "Detected in many" "ependymal cell: 34.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077492 Enhanced NA NA "Cluster 21: Testis - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" "HPA077492: " "unprognostic (1.11e-1)" "unprognostic (1.07e-3)" "unprognostic (4.10e-3)" "unprognostic (7.41e-2)" "unprognostic (1.09e-1)" "unprognostic (5.30e-2)" "potential prognostic unfavorable (5.25e-4)" "unprognostic (8.50e-3)" "unprognostic (2.89e-2)" "unprognostic (7.96e-2)" "unprognostic (1.74e-1)" "unprognostic (9.24e-2)" "unprognostic (2.88e-1)" "unprognostic (6.70e-2)" "unprognostic (2.14e-1)" "unprognostic (1.88e-2)" "unprognostic (1.39e-2)" "unprognostic (6.67e-2)" PPP1R37 LRRC68 ENSG00000104866 "Protein phosphatase 1 regulatory subunit 37" O75864 19 45091396-45148077 "Predicted intracellular proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 1.8;Cone photoreceptor cells: 2.1;Conjunctival goblet cells: 1.9;Epicardial cells: 2.3;pDCs: 1.8;Prostatic hillock cells: 1.9;Respiratory deuterosomal cells: 2.1;Retinal horizontal cells: 4.0;Urothelial cells: 2.2" "Cell type enhanced" "Detected in single" "upper rhombic lip: 1.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041500 Approved Approved Cytosol NA NA "Cluster 64: Non-specific - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 14 Cytosol "HPA041500: " "unprognostic (1.52e-3)" "unprognostic (3.01e-2)" "unprognostic (9.88e-2)" "unprognostic (6.93e-2)" "unprognostic (2.35e-2)" "unprognostic (1.69e-1)" "unprognostic (2.90e-1)" "unprognostic (2.65e-1)" "unprognostic (1.14e-1)" "potential prognostic favorable (1.09e-4)" "unprognostic (1.28e-1)" "unprognostic (6.36e-2)" "potential prognostic unfavorable (1.95e-5)" "unprognostic (3.98e-2)" "unprognostic (1.80e-1)" "unprognostic (1.11e-1)" "unprognostic (5.30e-2)" "unprognostic (6.06e-3)" "unprognostic (2.29e-1)" "unprognostic (8.70e-3)" "unprognostic (1.55e-1)" "unprognostic (2.21e-2)" "unprognostic (8.18e-2)" "unprognostic (3.36e-1)" "unprognostic (7.27e-2)" "unprognostic (7.92e-2)" "unprognostic (1.43e-1)" "unprognostic (1.17e-1)" "unprognostic (1.32e-1)" PPP1R3A "GM, PPP1R3" ENSG00000154415 "Protein phosphatase 1 regulatory subunit 3A" Q16821 7 113876777-114075920 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism, Glycogen metabolism" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 63 "heart muscle: 38.2;skeletal muscle: 143.1;tongue: 97.2" "Group enriched" "Detected in some" 7 "Cardiomyocytes: 154.5;Myonuclei: 583.4;Thymic myoid cells: 157.7" "Cell type enhanced" "Detected in some" "ependymal cell: 3.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes" "Region enriched" "Detected in single" 12 "thalamus: 1.1" "Not detected" "Not detected" "HPA070440, HPA073138" Enhanced NA NA "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 23: Non-specific - Transcription" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 5 "HPA070440: , HPA073138: " PPP1R3B "FLJ14005, GL, PPP1R4" ENSG00000173281 "Protein phosphatase 1 regulatory subunit 3B" Q86XI6 8 9136255-9151574 "Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 135.4;skeletal muscle: 89.2" "Cell type enhanced" "Detected in some" "Bergmann glia: 6.5;Choroid plexus epithelial cells: 11.4;Distal convoluted tubule cells: 9.4;Loop of henle epithelial cells: 22.2;Microglia: 8.7;Oligodendrocyte progenitor cells: 7.1;Papillary tip epithelial cells: 18.4;Podocytes: 17.0;Proximal tubule cells: 13.0;Renal collecting duct principal cells: 17.1;Renal connecting tubule cells: 11.9" "Cell type enhanced" "Detected in many" "endothelial cell: 15.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 15 "basophil: 53.3;eosinophil: 15.7;neutrophil: 50.2" "Lineage enriched" "Detected in all" 19 "granulocytes: 53.3" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Spleen - Neutrophils_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA028731 Enhanced Approved Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 12: Non-specific - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 14 Cytosol "HPA028731: " "unprognostic (1.13e-1)" "unprognostic (3.09e-2)" "unprognostic (1.81e-2)" "unprognostic (2.68e-3)" "unprognostic (3.29e-1)" "unprognostic (3.53e-2)" "unprognostic (3.40e-1)" "potential prognostic unfavorable (5.61e-4)" "unprognostic (5.27e-2)" "unprognostic (2.89e-2)" "unprognostic (9.49e-3)" "unprognostic (4.61e-2)" "unprognostic (2.91e-3)" "unprognostic (3.49e-2)" "unprognostic (2.31e-3)" "unprognostic (2.49e-1)" "unprognostic (2.04e-1)" "unprognostic (2.53e-1)" "unprognostic (1.72e-2)" "validated prognostic unfavorable (1.50e-5)" "validated prognostic unfavorable (5.26e-4)" "unprognostic (1.55e-3)" "unprognostic (1.30e-1)" "unprognostic (8.45e-2)" "unprognostic (1.77e-2)" "unprognostic (4.13e-2)" "unprognostic (1.25e-2)" "potential prognostic unfavorable (4.93e-4)" "unprognostic (3.46e-1)" "unprognostic (4.47e-2)" "unprognostic (9.48e-2)" PPP1R3C "PPP1R5, PTG" ENSG00000119938 "Protein phosphatase 1 regulatory subunit 3C" Q9UQK1 10 91628442-91633071 "Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 850.6;tongue: 419.1" "Cell type enhanced" "Detected in many" "Astrocytes: 139.6;Esophageal apical cells: 1168.9;Müller glia: 227.3;Myonuclei: 393.4" "Cell type enriched" "Detected in many" 5 "astrocyte: 147.8" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 43.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 28.3;cervical cancer: 36.5" "Adipose subcutaneous - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027041, HPA043875" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 19: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 84: Apical squamous epithelium - Cornification" 19 Cytosol "Nucleoplasm, Plasma membrane" "HPA027041: , HPA043875: " "unprognostic (1.24e-2)" "unprognostic (1.22e-1)" "unprognostic (3.42e-1)" "unprognostic (1.93e-1)" "unprognostic (1.43e-2)" "unprognostic (3.04e-1)" "unprognostic (6.69e-2)" "unprognostic (6.49e-2)" "unprognostic (1.53e-2)" "unprognostic (4.18e-3)" "unprognostic (3.06e-2)" "unprognostic (4.29e-2)" "unprognostic (2.05e-2)" "unprognostic (5.73e-3)" "unprognostic (2.66e-1)" "unprognostic (1.28e-2)" "unprognostic (3.52e-2)" "unprognostic (6.35e-2)" "unprognostic (8.34e-3)" "unprognostic (5.66e-3)" "unprognostic (3.09e-3)" "unprognostic (5.63e-3)" "unprognostic (1.09e-1)" "unprognostic (6.07e-2)" "unprognostic (3.11e-3)" "unprognostic (4.33e-2)" "unprognostic (8.17e-2)" "unprognostic (7.07e-3)" "unprognostic (1.40e-1)" "unprognostic (6.01e-2)" "unprognostic (4.76e-2)" PPP1R3D PPP1R6 ENSG00000132825 "Protein phosphatase 1 regulatory subunit 3D" O95685 20 59936663-59940305 "Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 46.1;Megakaryocytes: 37.1;Neutrophil progenitors: 52.9;Neutrophils: 102.9" "Cell type enhanced" "Detected in many" "Bergmann glia: 21.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 3.0" "Group enriched" "Detected in many" 4 "granulocytes: 3.0;monocytes: 1.9" "Low cancer specificity" "Detected in all" "Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041146 Approved Approved "Nucleoli,Vesicles,Mitochondria,Cytosol,Calyx,Connecting piece,Flagellar centriole,Mid piece,Principal piece" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 19: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 12 "Vesicles, Mitochondria, Calyx" "Nucleoli, Cytosol, Connecting piece, Flagellar centriole, Mid piece, Principal piece" "HPA041146: " "unprognostic (1.57e-1)" "unprognostic (2.35e-3)" "unprognostic (5.95e-2)" "unprognostic (2.98e-2)" "unprognostic (2.12e-1)" "unprognostic (1.27e-1)" "unprognostic (6.91e-2)" "potential prognostic unfavorable (9.25e-6)" "unprognostic (4.30e-2)" "unprognostic (5.99e-2)" "potential prognostic favorable (3.44e-6)" "unprognostic (5.17e-2)" "unprognostic (1.88e-1)" "unprognostic (2.23e-3)" "unprognostic (2.28e-2)" "unprognostic (4.49e-1)" "unprognostic (9.79e-3)" "unprognostic (2.22e-2)" "unprognostic (4.41e-2)" "unprognostic (1.70e-2)" "unprognostic (1.10e-1)" "unprognostic (1.75e-1)" "unprognostic (9.29e-2)" "unprognostic (1.26e-2)" "unprognostic (9.95e-3)" "unprognostic (8.48e-2)" "unprognostic (1.89e-2)" "unprognostic (3.06e-2)" "unprognostic (4.20e-2)" "unprognostic (1.72e-1)" PPP1R3E FLJ00089 ENSG00000235194 "Protein phosphatase 1 regulatory subunit 3E" Q9H7J1 14 23295652-23302859 "Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 43.4" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 72.7;Early spermatids: 105.4;Late spermatids: 59.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Spleen - B-cells (Spleen)" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA061600 Approved Approved "Microtubules,Mitotic spindle,Mitochondria" Yes No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 3 "Microtubules, Mitochondria" "Mitotic spindle" "HPA061600: " "unprognostic (2.59e-2)" "unprognostic (1.53e-2)" "unprognostic (3.68e-1)" "unprognostic (2.18e-2)" "potential prognostic unfavorable (1.54e-6)" "unprognostic (1.23e-1)" "unprognostic (2.03e-2)" "unprognostic (9.00e-2)" "potential prognostic favorable (2.31e-4)" "unprognostic (1.89e-1)" "unprognostic (1.56e-1)" "unprognostic (2.04e-2)" "unprognostic (3.70e-2)" "unprognostic (1.02e-1)" "unprognostic (8.90e-2)" "unprognostic (7.71e-3)" "unprognostic (1.07e-1)" "unprognostic (5.73e-3)" "unprognostic (7.23e-2)" "unprognostic (2.68e-1)" "unprognostic (5.75e-2)" "unprognostic (1.23e-3)" "unprognostic (2.03e-2)" "unprognostic (2.12e-1)" "unprognostic (1.52e-1)" "unprognostic (2.19e-1)" "unprognostic (1.62e-2)" "unprognostic (7.01e-2)" "unprognostic (9.57e-2)" "unprognostic (1.40e-1)" "unprognostic (1.83e-1)" PPP1R3F Hb2E ENSG00000049769 "Protein phosphatase 1 regulatory subunit 3F" Q6ZSY5 X 49269793-49301461 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.8" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 109.4;Oligodendrocytes: 40.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "T-reg: 9.4" "Lineage enriched" "Detected in single" 12 "T-cells: 9.4" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000244, HPA000918, HPA075936" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 34: Non-specific - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" 3 "Nucleoplasm, Vesicles" "HPA000244: , HPA000918: , HPA075936: " "unprognostic (6.75e-2)" "unprognostic (3.82e-2)" "unprognostic (1.13e-1)" "unprognostic (1.89e-1)" "unprognostic (4.78e-2)" "unprognostic (2.16e-1)" "unprognostic (2.95e-2)" "unprognostic (1.13e-2)" "unprognostic (6.35e-2)" "unprognostic (1.44e-1)" "unprognostic (1.75e-1)" "unprognostic (4.72e-2)" "unprognostic (1.54e-1)" "unprognostic (3.40e-1)" "unprognostic (2.54e-1)" "unprognostic (4.46e-2)" "unprognostic (2.43e-2)" "unprognostic (1.36e-1)" "unprognostic (3.53e-2)" "unprognostic (1.97e-1)" "unprognostic (4.14e-1)" "potential prognostic favorable (8.89e-4)" "unprognostic (1.94e-2)" "unprognostic (3.09e-1)" "unprognostic (2.79e-1)" "unprognostic (7.52e-2)" "unprognostic (1.14e-1)" "unprognostic (8.12e-2)" "unprognostic (2.00e-1)" "unprognostic (1.00e-1)" "unprognostic (2.49e-1)" PPP1R3G ENSG00000219607 "Protein phosphatase 1 regulatory subunit 3G" B7ZBB8 6 5085341-5089487 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 6.0" "Cell type enriched" "Detected in some" 5 "Esophageal apical cells: 66.7" "Cell type enhanced" "Detected in some" "astrocyte: 3.1;Bergmann glia: 2.6;central nervous system macrophage: 3.0" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 7.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Heart muscle - Cardiomyocytes, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA056393 Uncertain NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 84: Apical squamous epithelium - Cornification" "HPA056393: " "unprognostic (2.03e-2)" "unprognostic (1.43e-2)" "unprognostic (1.40e-3)" "potential prognostic favorable (5.27e-5)" "unprognostic (7.14e-2)" "unprognostic (1.01e-1)" "unprognostic (1.07e-1)" "unprognostic (6.61e-3)" "unprognostic (3.42e-2)" "potential prognostic favorable (7.00e-7)" "unprognostic (6.37e-3)" "unprognostic (8.45e-2)" "potential prognostic unfavorable (1.86e-8)" "unprognostic (5.37e-2)" "unprognostic (1.57e-2)" "unprognostic (6.04e-2)" "unprognostic (1.19e-1)" "unprognostic (1.12e-2)" "unprognostic (2.42e-1)" "unprognostic (2.46e-1)" "unprognostic (1.74e-3)" "unprognostic (1.36e-1)" PPP1R42 "dtr, LRRC67, TLLR" ENSG00000178125 "Protein phosphatase 1 regulatory subunit 42" Q7Z4L9 8 66964099-67056604 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 6 "fallopian tube: 5.1;testis: 8.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 136.9;Choroid plexus epithelial cells: 196.3;Early primary spermatocytes: 125.4;Endometrial ciliated cells: 109.8;Ependymal cells: 646.7;Epididymal efferent duct ciliated cells: 162.0;Fallopian tube ciliated cells: 243.3;Late primary spermatocytes: 283.2;Respiratory ciliated cells: 323.3" "Group enriched" "Detected in all" 10 "choroid plexus epithelial cell: 191.1;ependymal cell: 671.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA024313, HPA027983, HPA028628" Uncertain NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 34: Ciliated cells - Cilia assembly & function" "HPA024313: , HPA027983: , HPA028628: " "unprognostic (3.14e-2)" PPP1R7 sds22 ENSG00000115685 "Protein phosphatase 1 regulatory subunit 7" Q15435 2 241149576-241183652 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 980.7;Esophageal apical cells: 444.7;Late primary spermatocytes: 860.1;Late spermatids: 2387.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "HPA034500, HPA034501" Supported Approved Nucleoli NA NA 1400000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 33: Neurons - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 50 Nucleoli "HPA034500: , HPA034501: " "unprognostic (1.36e-1)" "unprognostic (6.73e-2)" "unprognostic (7.27e-2)" "unprognostic (4.48e-2)" "unprognostic (7.90e-2)" "unprognostic (1.77e-1)" "unprognostic (1.72e-1)" "unprognostic (7.46e-3)" "unprognostic (6.89e-2)" "unprognostic (1.28e-2)" "potential prognostic favorable (1.49e-4)" "unprognostic (7.97e-3)" "unprognostic (4.90e-3)" "validated prognostic unfavorable (1.84e-5)" "validated prognostic unfavorable (2.01e-4)" "unprognostic (9.38e-3)" "unprognostic (5.73e-2)" "unprognostic (3.74e-2)" "unprognostic (3.23e-1)" "unprognostic (5.42e-2)" "unprognostic (4.70e-2)" "unprognostic (2.97e-3)" "unprognostic (8.47e-2)" "unprognostic (1.71e-1)" "unprognostic (3.53e-3)" "unprognostic (2.89e-1)" "unprognostic (1.14e-1)" "unprognostic (4.01e-2)" "unprognostic (4.07e-2)" "unprognostic (4.13e-2)" "unprognostic (2.87e-1)" PPP1R8 "ard-1, ARD1, NIPP-1, NIPP1, PRO2047" ENSG00000117751 "Protein phosphatase 1 regulatory subunit 8" Q12972 1 27830782-27851676 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, Transcription, Transcription regulation" "DNA-binding, Endonuclease, Hydrolase, Nuclease, Protein phosphatase inhibitor, Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027406, HPA027417, HPA027452" Enhanced Enhanced "Nucleoplasm,Nuclear speckles" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 28 "Nuclear speckles" Nucleoplasm "HPA027406: , HPA027417: , HPA027452: " "unprognostic (3.65e-1)" "unprognostic (3.91e-2)" "unprognostic (7.85e-3)" "unprognostic (1.77e-2)" "unprognostic (1.76e-2)" "unprognostic (1.47e-1)" "unprognostic (2.23e-1)" "unprognostic (1.08e-2)" "unprognostic (9.73e-2)" "potential prognostic unfavorable (1.70e-4)" "potential prognostic favorable (3.33e-7)" "unprognostic (1.03e-3)" "unprognostic (3.32e-1)" "validated prognostic unfavorable (6.44e-7)" "validated prognostic unfavorable (1.61e-4)" "unprognostic (2.27e-1)" "unprognostic (6.84e-3)" "unprognostic (6.84e-2)" "unprognostic (3.44e-2)" "unprognostic (3.79e-2)" "unprognostic (1.26e-1)" "unprognostic (3.09e-2)" "unprognostic (3.01e-2)" "unprognostic (1.28e-2)" "unprognostic (8.34e-2)" "unprognostic (5.92e-3)" "unprognostic (3.61e-2)" "unprognostic (8.96e-2)" "unprognostic (2.36e-1)" "unprognostic (1.13e-1)" "unprognostic (7.73e-2)" PPP1R9A "FLJ20068, KIAA1222, Neurabin-I" ENSG00000158528 "Protein phosphatase 1 regulatory subunit 9A" Q9ULJ8 7 94907202-95296415 "Plasma proteins, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Actin-binding, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 17.2" "Cell type enhanced" "Detected in many" "Oligodendrocyte progenitor cells: 781.9;Salivary acinar cells: 817.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "basophil: 6.9;NK-cell: 10.3" "Group enriched" "Detected in many" 9 "granulocytes: 6.9;NK-cells: 10.3" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Spleen - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027726, HPA075591" Approved Approved "Plasma membrane" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 12 "Plasma membrane" "HPA027726: , HPA075591: " "unprognostic (3.93e-2)" "unprognostic (3.25e-1)" "unprognostic (1.74e-1)" "unprognostic (1.00e-1)" "unprognostic (5.29e-2)" "unprognostic (1.73e-1)" "unprognostic (1.58e-1)" "unprognostic (2.08e-2)" "unprognostic (5.37e-2)" "potential prognostic favorable (5.93e-4)" "unprognostic (1.83e-1)" "unprognostic (1.83e-1)" "unprognostic (6.46e-2)" "unprognostic (1.62e-2)" "unprognostic (7.58e-2)" "unprognostic (7.15e-2)" "unprognostic (1.36e-1)" "unprognostic (8.58e-2)" "unprognostic (2.49e-2)" "unprognostic (3.03e-2)" "unprognostic (3.23e-2)" "unprognostic (1.70e-1)" "unprognostic (3.13e-2)" "unprognostic (1.36e-1)" "unprognostic (3.46e-1)" "unprognostic (9.68e-2)" "unprognostic (2.90e-2)" "unprognostic (4.19e-2)" "unprognostic (2.53e-1)" PPP1R9B "PPP1R6, PPP1R9, SPINO, Spn" ENSG00000108819 "Protein phosphatase 1 regulatory subunit 9B" Q96SB3 17 50133737-50150677 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Actin-binding, Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 107.1" "Cell type enhanced" "Detected in many" "Kupffer cells: 60.5;monocytes: 47.5;Neutrophils: 40.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Liver - Vascular endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022461 Approved NA NA 52000 "Cluster 22: Eosinophils - Transcription" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 63 "CAB022461: " "unprognostic (2.85e-1)" "unprognostic (3.63e-1)" "unprognostic (3.83e-1)" "unprognostic (1.37e-1)" "unprognostic (8.52e-2)" "unprognostic (1.50e-1)" "unprognostic (3.01e-1)" "unprognostic (1.16e-2)" "unprognostic (1.00e-1)" "unprognostic (1.63e-1)" "potential prognostic favorable (8.76e-4)" "unprognostic (4.39e-2)" "unprognostic (4.22e-1)" "unprognostic (2.98e-3)" "unprognostic (2.99e-1)" "unprognostic (6.60e-2)" "unprognostic (7.41e-3)" "unprognostic (2.26e-2)" "unprognostic (6.16e-2)" "unprognostic (2.23e-1)" "unprognostic (1.54e-2)" "unprognostic (1.21e-2)" "unprognostic (1.19e-1)" "unprognostic (1.45e-1)" "unprognostic (7.99e-2)" "unprognostic (1.76e-2)" "unprognostic (1.27e-1)" "unprognostic (9.41e-2)" "unprognostic (3.65e-2)" "unprognostic (5.65e-2)" "unprognostic (3.45e-2)" PPP2CA "PP2AC, PP2Calpha" ENSG00000113575 "Protein phosphatase 2 catalytic subunit alpha" P67775 5 134194035-134226073 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Meiosis "Hydrolase, Protein phosphatase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 6.5;Megakaryocytes: 6.2;Tuft cells: 11.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003848, HPA043236" Approved NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 34: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 17: Non-specific - RNA processing" 287 "CAB003848: , HPA043236: " "unprognostic (8.09e-2)" "unprognostic (3.97e-2)" "unprognostic (4.87e-2)" "unprognostic (1.33e-1)" "unprognostic (3.68e-3)" "unprognostic (2.96e-2)" "unprognostic (2.49e-1)" "unprognostic (2.51e-2)" "unprognostic (1.78e-2)" "unprognostic (2.48e-3)" "potential prognostic favorable (1.42e-6)" "unprognostic (3.83e-3)" "unprognostic (2.12e-1)" "unprognostic (1.80e-3)" "potential prognostic unfavorable (5.47e-4)" "unprognostic (2.08e-3)" "unprognostic (2.70e-1)" "unprognostic (7.56e-3)" "unprognostic (1.11e-1)" "unprognostic (1.11e-1)" "unprognostic (6.76e-3)" "potential prognostic unfavorable (4.99e-4)" "unprognostic (7.15e-2)" "unprognostic (1.29e-1)" "unprognostic (6.27e-2)" "unprognostic (1.65e-1)" "unprognostic (3.24e-2)" "unprognostic (2.42e-1)" "unprognostic (3.89e-1)" "unprognostic (1.09e-1)" "unprognostic (8.45e-3)" PPP2CB PP2Abeta ENSG00000104695 "Protein phosphatase 2 catalytic subunit beta" P62714 8 30774457-30814314 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018600, HPA043236" Approved Supported Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 39: Astrocytes - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 94: Gonadal somatic cells - Mixed function" 137 Nucleoplasm "CAB018600: , HPA043236: " "unprognostic (2.09e-2)" "unprognostic (3.97e-1)" "unprognostic (4.55e-2)" "unprognostic (1.09e-1)" "unprognostic (1.43e-2)" "unprognostic (4.29e-2)" "unprognostic (3.08e-2)" "unprognostic (2.96e-1)" "unprognostic (2.99e-2)" "unprognostic (1.53e-1)" "potential prognostic favorable (3.75e-9)" "unprognostic (2.17e-3)" "unprognostic (6.29e-2)" "potential prognostic unfavorable (1.62e-4)" "unprognostic (2.40e-1)" "unprognostic (2.42e-1)" "unprognostic (5.02e-2)" "unprognostic (4.41e-2)" "unprognostic (7.20e-2)" "unprognostic (3.80e-1)" "unprognostic (1.62e-2)" "unprognostic (3.19e-2)" "unprognostic (1.69e-1)" "unprognostic (8.19e-2)" "unprognostic (1.94e-1)" "unprognostic (8.01e-2)" "unprognostic (5.86e-2)" "unprognostic (1.13e-2)" "unprognostic (2.55e-1)" "unprognostic (2.22e-1)" "unprognostic (2.56e-1)" PPP2R1A "PP2A-Aalpha, PP2AA, PR65A" ENSG00000105568 "Protein phosphatase 2 scaffold subunit Aalpha" P30153 19 52170936-52229518 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Chromosome partition, Host-virus interaction" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 661.1;Extravillous trophoblasts: 342.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Smooth muscle cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB018599 Approved Cytosol NA NA 1800000 "Cluster 25: Non-specific - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 38: Sub-cortical - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 271 Cytosol "CAB018599: " "unprognostic (1.06e-1)" "unprognostic (1.54e-1)" "unprognostic (5.80e-2)" "unprognostic (4.05e-2)" "unprognostic (1.35e-1)" "unprognostic (7.28e-2)" "unprognostic (2.46e-1)" "unprognostic (3.11e-1)" "unprognostic (1.25e-2)" "unprognostic (3.88e-1)" "unprognostic (1.67e-1)" "unprognostic (3.73e-1)" "potential prognostic favorable (3.98e-4)" "validated prognostic unfavorable (1.94e-5)" "validated prognostic unfavorable (1.86e-5)" "unprognostic (3.92e-3)" "unprognostic (1.04e-2)" "unprognostic (1.21e-1)" "unprognostic (4.62e-2)" "unprognostic (3.82e-1)" "unprognostic (2.05e-2)" "unprognostic (7.98e-3)" "unprognostic (1.15e-1)" "unprognostic (2.46e-1)" "unprognostic (1.63e-1)" "unprognostic (3.23e-1)" "unprognostic (2.53e-2)" "unprognostic (3.13e-1)" "unprognostic (2.61e-2)" "unprognostic (2.56e-2)" "unprognostic (3.22e-1)" PPP2R1B "PP2A-Abeta, PR65B" ENSG00000137713 "Protein phosphatase 2 scaffold subunit Abeta" P30154 11 111726908-111766389 "Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 152.7" "Cell type enhanced" "Detected in all" "Adipocytes: 702.9;Early spermatids: 287.6;Late primary spermatocytes: 359.8;Late spermatids: 218.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Skin - Hair cortex cells, Skin - Inner root sheath cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004034, HPA018908" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 55: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 89: Adipocytes - Lipid metabolism" 79 "Plasma membrane, Cytosol" "CAB004034: , HPA018908: " "unprognostic (9.09e-2)" "unprognostic (1.27e-1)" "unprognostic (4.41e-3)" "unprognostic (1.69e-3)" "unprognostic (2.82e-2)" "unprognostic (1.13e-1)" "unprognostic (8.19e-2)" "unprognostic (1.87e-1)" "unprognostic (2.12e-1)" "unprognostic (4.61e-3)" "potential prognostic favorable (4.95e-7)" "unprognostic (2.25e-3)" "unprognostic (1.25e-2)" "potential prognostic favorable (1.63e-4)" "unprognostic (2.72e-3)" "unprognostic (1.92e-2)" "unprognostic (2.42e-3)" "unprognostic (1.25e-1)" "unprognostic (8.41e-2)" "unprognostic (8.34e-2)" "unprognostic (1.09e-1)" "unprognostic (1.02e-1)" "unprognostic (1.67e-2)" "unprognostic (3.33e-2)" "unprognostic (2.29e-2)" "unprognostic (6.86e-2)" "potential prognostic unfavorable (3.66e-4)" "unprognostic (9.68e-2)" "unprognostic (4.89e-1)" "unprognostic (7.00e-2)" "unprognostic (1.16e-2)" PPP2R2A "B55A, B55alpha, PR52A, PR55A, PR55alpha" ENSG00000221914 "Protein phosphatase 2 regulatory subunit Balpha" P63151 8 26291508-26372680 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 888.6;Neutrophils: 737.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042122, HPA042770, CAB079289" Approved Approved Cytosol NA NA 18000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 67 Cytosol "CAB079289: , HPA042122: , HPA042770: " "unprognostic (1.94e-2)" "unprognostic (1.75e-1)" "unprognostic (1.57e-1)" "unprognostic (2.10e-1)" "unprognostic (9.47e-3)" "unprognostic (1.98e-1)" "unprognostic (1.00e-1)" "unprognostic (6.96e-2)" "unprognostic (3.12e-2)" "potential prognostic unfavorable (3.01e-4)" "potential prognostic favorable (1.96e-9)" "unprognostic (2.73e-3)" "unprognostic (1.47e-1)" "unprognostic (4.60e-2)" "unprognostic (1.28e-1)" "unprognostic (1.47e-1)" "unprognostic (8.01e-2)" "unprognostic (1.31e-1)" "unprognostic (1.33e-1)" "unprognostic (5.70e-2)" "unprognostic (9.81e-3)" "unprognostic (4.22e-3)" "unprognostic (2.86e-3)" "unprognostic (6.44e-2)" "unprognostic (2.19e-2)" "unprognostic (1.75e-1)" "unprognostic (2.87e-1)" "unprognostic (2.88e-1)" "unprognostic (1.13e-1)" "unprognostic (1.21e-1)" "unprognostic (4.47e-2)" PPP2R2B "B55beta, PR52B, PR55-BETA, SCA12" ENSG00000156475 "Protein phosphatase 2 regulatory subunit Bbeta" Q00005 5 146580742-147084784 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Apoptosis "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 59.7;retina: 39.7;testis: 17.6" "Cell type enhanced" "Detected in many" "Astrocytes: 2900.2;Bergmann glia: 4881.4;Brain inhibitory neurons: 1044.9;Cone photoreceptor cells: 1455.3;Late spermatids: 1600.0;Oligodendrocyte progenitor cells: 1290.5;Oligodendrocytes: 6649.5;Pituitary stem cells: 3199.0;Rod photoreceptor cells: 1820.9;Schwann cells: 1176.7" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 7526.3;oligodendrocyte: 6557.0" "Cancer enriched" "Detected in many" 10 "Glioblastoma Multiforme (TCGA): 46.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "gdT-cell: 5.2;MAIT T-cell: 4.1;memory CD4 T-cell: 2.4;memory CD8 T-cell: 6.2;naive CD8 T-cell: 3.8;NK-cell: 2.9;T-reg: 3.4" "Group enriched" "Detected in many" 9 "NK-cells: 2.9;T-cells: 6.2" "Cancer enhanced" "Detected in many" "cervical cancer: 6.2" "Adipose subcutaneous - Smooth muscle cells, Prostate - Smooth muscle cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038118, HPA042122, HPA042770" Approved Approved Cytosol NA NA "Cluster 1: T-cells - Unknown function" "Cluster 73: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 41 Cytosol "HPA038118: , HPA042122: , HPA042770: " "unprognostic (3.10e-1)" "unprognostic (1.12e-1)" "unprognostic (2.06e-1)" "unprognostic (3.27e-2)" "unprognostic (2.25e-1)" "unprognostic (6.41e-2)" "unprognostic (2.05e-2)" "unprognostic (4.69e-2)" "unprognostic (3.39e-1)" "unprognostic (2.39e-1)" "unprognostic (2.31e-1)" "unprognostic (1.24e-1)" "potential prognostic favorable (7.17e-6)" "unprognostic (6.61e-2)" "unprognostic (7.55e-2)" "unprognostic (7.69e-2)" "unprognostic (1.23e-1)" "potential prognostic unfavorable (3.75e-4)" "unprognostic (1.61e-1)" PPP2R2C "B55gamma, IMYPNO, MGC33570, PR52, PR55G" ENSG00000074211 "Protein phosphatase 2 regulatory subunit Bgamma" Q9Y2T4 4 6320578-6563600 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 112.0" "Cell type enhanced" "Detected in many" "Astrocytes: 97.4;Brain excitatory neurons: 200.1;Brain inhibitory neurons: 254.9;Corticotrophs: 98.6;Early spermatids: 108.1;Ependymal cells: 127.0;Esophageal apical cells: 337.9;Esophageal suprabasal cells: 104.6;Gonadotrophs: 120.9;Lactotrophs: 154.7;Late spermatids: 318.5;Ocular epithelial cells: 110.5;Other brain neurons: 140.7;Retinal ganglion cells: 208.6;Thyrotrophs: 127.6" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 35.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Pancreas - Alpha cells, Pancreas - Beta cells, Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042122, HPA042770, HPA060473" Approved Approved Cytosol NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 7: Liver cancer - Metabolism" "Cluster 35: Neurons - Synaptic function & neurogenesis" 24 Cytosol "HPA042122: , HPA042770: , HPA060473: " "unprognostic (7.46e-2)" "unprognostic (1.50e-2)" "unprognostic (4.69e-2)" "unprognostic (1.85e-2)" "unprognostic (4.81e-2)" "unprognostic (3.98e-2)" "unprognostic (5.40e-2)" "unprognostic (2.94e-2)" "unprognostic (9.10e-2)" "potential prognostic unfavorable (5.52e-13)" "potential prognostic unfavorable (8.98e-4)" "potential prognostic unfavorable (3.57e-4)" "unprognostic (8.00e-2)" "unprognostic (9.17e-3)" "unprognostic (1.34e-1)" "unprognostic (1.94e-2)" "unprognostic (3.59e-1)" "unprognostic (1.77e-1)" "unprognostic (7.66e-3)" "unprognostic (4.21e-2)" "unprognostic (6.44e-2)" "unprognostic (4.18e-1)" "unprognostic (1.26e-1)" "unprognostic (6.61e-2)" "unprognostic (1.01e-1)" "unprognostic (2.72e-1)" "unprognostic (3.70e-1)" "unprognostic (1.87e-2)" PPP2R2D "B55D, B55delta, MDS026" ENSG00000175470 "Protein phosphatase 2 regulatory subunit Bdelta" Q66LE6 10 131901008-131959834 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 15.0" "Cell type enhanced" "Detected in all" "Pancreatic acinar cells: 328.1;Somatotrophs: 332.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042122, HPA042770" Approved Approved Cytosol NA NA "Cluster 70: Non-specific - Protein processing" "Cluster 15: Non-specific - Transcription" "Cluster 56: Non-specific - Sensory perception" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 87 Cytosol "HPA042122: , HPA042770: " "unprognostic (6.28e-2)" "unprognostic (1.05e-1)" "unprognostic (5.02e-1)" "unprognostic (1.46e-1)" "unprognostic (8.35e-2)" "unprognostic (2.10e-1)" "potential prognostic favorable (6.34e-5)" "unprognostic (2.59e-1)" "unprognostic (4.12e-2)" "potential prognostic favorable (4.41e-4)" "unprognostic (1.30e-2)" "unprognostic (5.87e-3)" "unprognostic (3.88e-2)" "unprognostic (1.22e-1)" "unprognostic (3.32e-2)" "unprognostic (4.47e-3)" "unprognostic (2.80e-2)" "unprognostic (2.72e-1)" "unprognostic (1.45e-1)" "unprognostic (2.17e-1)" "unprognostic (1.14e-1)" "unprognostic (1.31e-1)" PPP2R3A "PPP2R3, PR130, PR72" ENSG00000073711 "Protein phosphatase 2 regulatory subunit B''alpha" Q06190 3 135965728-136147894 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "heart muscle: 47.9;skeletal muscle: 168.9;tongue: 110.0" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 753.9;Loop of henle epithelial cells: 560.9;Myonuclei: 1307.1;Proximal tubule cells: 701.8;Renal collecting duct intercalated cells: 440.1;Renal connecting tubule cells: 720.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035829, HPA035830, HPA065338" Uncertain Approved "Golgi apparatus,Flagellar centriole,Mid piece" NA NA "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 9 "Golgi apparatus" "Flagellar centriole, Mid piece" "HPA035829: , HPA035830: , HPA065338: " "unprognostic (2.90e-1)" "unprognostic (3.01e-1)" "unprognostic (2.23e-2)" "unprognostic (1.10e-1)" "unprognostic (7.54e-2)" "unprognostic (1.17e-2)" "unprognostic (3.78e-1)" "potential prognostic favorable (1.60e-4)" "unprognostic (3.78e-1)" "unprognostic (4.21e-3)" "potential prognostic favorable (3.26e-7)" "unprognostic (1.19e-1)" "potential prognostic favorable (3.52e-5)" "unprognostic (3.75e-3)" "unprognostic (1.21e-1)" "unprognostic (2.77e-3)" "unprognostic (1.23e-1)" "unprognostic (7.08e-2)" "unprognostic (8.25e-2)" "unprognostic (2.18e-2)" "potential prognostic unfavorable (1.19e-4)" "unprognostic (1.01e-1)" "unprognostic (1.01e-1)" "unprognostic (1.37e-1)" "unprognostic (2.26e-1)" "unprognostic (1.82e-1)" "unprognostic (5.58e-2)" "unprognostic (8.39e-3)" "unprognostic (1.24e-1)" "unprognostic (5.12e-2)" PPP2R3B "PPP2R3L, PPP2R3LY, PR48, PR70" ENSG00000167393 "Protein phosphatase 2 regulatory subunit B''beta" Q9Y5P8 X 333933-386955 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "heart muscle: 59.2;skeletal muscle: 87.3" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 12.8;Early primary spermatocytes: 16.9;Loop of henle epithelial cells: 12.8;Oocytes: 32.2;Papillary tip epithelial cells: 12.9;Proximal tubule cells: 13.9;Renal collecting duct intercalated cells: 14.7;Renal collecting duct principal cells: 14.3;Renal connecting tubule cells: 15.8;Thymic myoid cells: 32.6;Undifferentiated spermatogonia: 12.4" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" HPA026606 Supported "Nucleoplasm,Primary cilium,Primary cilium tip,Cytosol" NA NA "Cluster 68: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 105: Non-specific - Mixed function" 16 Nucleoplasm "Primary cilium, Primary cilium tip, Cytosol" "HPA026606: " "unprognostic (2.54e-1)" "unprognostic (1.14e-1)" "unprognostic (1.25e-1)" "unprognostic (2.89e-2)" "unprognostic (5.79e-2)" "unprognostic (2.92e-2)" "unprognostic (1.10e-1)" "unprognostic (9.81e-2)" "unprognostic (1.15e-1)" "unprognostic (3.55e-2)" "unprognostic (4.36e-2)" "unprognostic (1.23e-1)" "unprognostic (8.79e-3)" "unprognostic (1.75e-1)" "unprognostic (3.70e-2)" "unprognostic (2.51e-1)" "unprognostic (7.59e-3)" "unprognostic (6.02e-3)" "unprognostic (2.29e-1)" "unprognostic (5.27e-2)" "unprognostic (1.10e-1)" PPP2R3C "C14orf10, FLJ20644, G4-1, G5PR" ENSG00000092020 "Protein phosphatase 2 regulatory subunit B''gamma" Q969Q6 14 35085467-35122517 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Cone-rod dystrophy, Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 467.0;Epicardial cells: 1244.0;Late primary spermatocytes: 615.6;Late spermatids: 286.4;Neutrophils: 387.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040835, HPA058834" Approved Supported "Nucleoplasm,Nuclear bodies,Golgi apparatus,Actin filaments,Primary cilium,Cytosol" No No "Cluster 42: Non-specific - Vesicular transport" "Cluster 39: Testis - Nuclear processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 17 Nucleoplasm "Nuclear bodies, Golgi apparatus, Actin filaments, Primary cilium, Cytosol" "HPA040835: , HPA058834: " "unprognostic (3.57e-1)" "unprognostic (3.23e-2)" "unprognostic (7.11e-2)" "unprognostic (1.51e-2)" "unprognostic (2.62e-1)" "unprognostic (1.92e-1)" "unprognostic (1.72e-1)" "unprognostic (7.75e-2)" "unprognostic (2.28e-2)" "unprognostic (5.91e-2)" "unprognostic (1.03e-2)" "unprognostic (1.66e-1)" "unprognostic (9.43e-2)" "unprognostic (3.43e-3)" "unprognostic (3.27e-2)" "unprognostic (2.90e-1)" "unprognostic (3.61e-2)" "unprognostic (2.31e-1)" "unprognostic (5.96e-2)" "unprognostic (6.17e-2)" "unprognostic (1.33e-1)" "unprognostic (7.34e-2)" "unprognostic (4.29e-2)" "unprognostic (7.65e-2)" "unprognostic (2.17e-1)" "unprognostic (2.06e-1)" "unprognostic (4.48e-2)" "unprognostic (2.35e-1)" "unprognostic (1.36e-2)" "unprognostic (1.82e-2)" "unprognostic (6.56e-2)" PPP2R5A "B56A, B56alpha, PR61A" ENSG00000066027 "Protein phosphatase 2 regulatory subunit B'alpha" Q15172 1 212285410-212361853 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 902.4;Neutrophil progenitors: 631.6;Neutrophils: 500.6;Renal collecting duct intercalated cells: 353.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Lung - Alveolar cells type 1, Prostate - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059288, HPA078841" Approved Supported Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 19: Astrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 51 Cytosol "HPA059288: , HPA078841: " "unprognostic (1.46e-2)" "unprognostic (4.68e-2)" "unprognostic (1.39e-1)" "unprognostic (1.48e-2)" "unprognostic (1.65e-3)" "unprognostic (1.33e-1)" "unprognostic (1.74e-1)" "potential prognostic favorable (7.46e-4)" "unprognostic (1.03e-1)" "unprognostic (7.09e-2)" "validated prognostic favorable (6.60e-6)" "validated prognostic favorable (8.84e-4)" "unprognostic (7.90e-3)" "unprognostic (7.73e-2)" "unprognostic (2.27e-3)" "unprognostic (1.18e-2)" "unprognostic (3.82e-1)" "unprognostic (1.34e-1)" "unprognostic (7.81e-2)" "unprognostic (2.42e-1)" "unprognostic (1.72e-2)" "unprognostic (2.49e-1)" "unprognostic (1.88e-1)" "unprognostic (5.72e-2)" "unprognostic (2.08e-2)" "unprognostic (7.20e-2)" "unprognostic (7.50e-2)" "unprognostic (1.59e-1)" "unprognostic (1.29e-1)" "unprognostic (3.66e-1)" "unprognostic (2.84e-2)" PPP2R5B "B56B, B56beta, FLJ35411, PR61B" ENSG00000068971 "Protein phosphatase 2 regulatory subunit B'beta" Q15173 11 64917553-64934475 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "brain: 112.8" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "eosinophil: 8.9" "Lineage enriched" "Detected in many" 7 "granulocytes: 8.9" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036607 Approved NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 27: Cerebellum - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 24: Non-specific - Unknown function" "Cluster 109: Neurons - Neuronal signaling" 12 "HPA036607: " "unprognostic (1.59e-1)" "unprognostic (1.23e-2)" "unprognostic (2.46e-2)" "unprognostic (6.54e-2)" "unprognostic (6.69e-2)" "unprognostic (5.33e-2)" "unprognostic (1.93e-1)" "unprognostic (1.38e-1)" "unprognostic (3.85e-1)" "unprognostic (2.43e-1)" "unprognostic (2.73e-1)" "unprognostic (2.00e-1)" "potential prognostic favorable (7.49e-5)" "potential prognostic unfavorable (4.49e-6)" "unprognostic (6.63e-2)" "unprognostic (4.54e-1)" "unprognostic (2.64e-2)" "unprognostic (2.89e-2)" "unprognostic (7.36e-2)" "unprognostic (4.56e-1)" "unprognostic (2.41e-1)" "unprognostic (1.93e-2)" "unprognostic (1.53e-1)" "unprognostic (6.35e-2)" "unprognostic (2.61e-2)" "unprognostic (1.99e-1)" "unprognostic (1.14e-1)" "unprognostic (2.90e-1)" "unprognostic (9.18e-2)" "unprognostic (1.94e-2)" "unprognostic (4.56e-2)" PPP2R5C "B56G, B56gamma, PR61G" ENSG00000078304 "Protein phosphatase 2 regulatory subunit B'gamma" Q13362 14 101761709-101927989 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 604.4;NK-cells: 888.6;T-cells: 950.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027553 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 51: Neurons - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 9: T-cells - Adaptive immunity: Regulation" 28 "Nucleoplasm, Cytosol" "Golgi apparatus" "HPA027553: " "unprognostic (2.27e-1)" "unprognostic (2.57e-1)" "unprognostic (6.72e-2)" "unprognostic (5.09e-2)" "unprognostic (1.16e-1)" "unprognostic (3.32e-2)" "unprognostic (1.73e-1)" "unprognostic (3.49e-3)" "unprognostic (4.43e-2)" "potential prognostic unfavorable (1.72e-4)" "unprognostic (2.01e-2)" "unprognostic (2.74e-2)" "unprognostic (9.73e-2)" "unprognostic (6.71e-2)" "unprognostic (2.23e-1)" "unprognostic (7.80e-2)" "unprognostic (3.09e-1)" "unprognostic (1.88e-1)" "unprognostic (7.32e-2)" "unprognostic (3.89e-2)" "unprognostic (2.40e-3)" "unprognostic (1.95e-2)" "unprognostic (1.22e-2)" "unprognostic (4.85e-2)" "unprognostic (2.59e-1)" "unprognostic (4.00e-2)" "unprognostic (1.83e-2)" "unprognostic (5.06e-2)" "unprognostic (1.00e-1)" "unprognostic (2.34e-1)" "unprognostic (2.72e-1)" PPP2R5D "B56D, B56delta" ENSG00000112640 "Protein phosphatase 2 regulatory subunit B'delta" Q14738 6 42984553-43012342 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029045, HPA029046" Approved Supported Nucleoplasm,Cytosol NA NA 24000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 26 Cytosol Nucleoplasm "HPA029045: , HPA029046: " "unprognostic (4.77e-1)" "unprognostic (1.42e-1)" "unprognostic (1.03e-1)" "unprognostic (6.38e-2)" "unprognostic (2.82e-2)" "unprognostic (1.83e-1)" "unprognostic (3.87e-2)" "unprognostic (3.86e-2)" "unprognostic (1.19e-1)" "unprognostic (2.38e-1)" "validated prognostic favorable (5.21e-5)" "validated prognostic favorable (9.28e-4)" "unprognostic (1.67e-1)" "unprognostic (1.35e-3)" "potential prognostic unfavorable (1.58e-4)" "unprognostic (8.00e-2)" "unprognostic (6.42e-2)" "unprognostic (1.09e-1)" "unprognostic (1.04e-1)" "unprognostic (1.99e-1)" "unprognostic (1.31e-1)" "unprognostic (1.28e-1)" "unprognostic (8.60e-2)" "unprognostic (1.43e-1)" "unprognostic (2.37e-3)" "unprognostic (1.91e-1)" "unprognostic (1.52e-1)" "unprognostic (1.62e-1)" "unprognostic (2.72e-1)" "unprognostic (1.28e-2)" "unprognostic (7.08e-2)" PPP2R5E "B56E, B56epsilon" ENSG00000154001 "Protein phosphatase 2 regulatory subunit B'epsilon" Q16537 14 63371364-63543377 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006034, CAB072342" Approved Supported "Cytosol,Mid piece,Principal piece" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 42: Retina - Visual perception" "Cluster 14: Neurons - Synaptic function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 34 Cytosol "Mid piece, Principal piece" "CAB072342: , HPA006034: " "unprognostic (3.44e-2)" "unprognostic (1.86e-1)" "unprognostic (4.70e-2)" "unprognostic (4.66e-3)" "unprognostic (9.48e-2)" "unprognostic (4.66e-3)" "unprognostic (5.06e-2)" "unprognostic (1.43e-1)" "unprognostic (2.27e-1)" "unprognostic (6.89e-3)" "potential prognostic favorable (5.71e-5)" "unprognostic (8.23e-3)" "unprognostic (2.30e-1)" "potential prognostic unfavorable (3.96e-5)" "unprognostic (1.89e-1)" "unprognostic (3.87e-3)" "unprognostic (9.51e-3)" "unprognostic (2.20e-1)" "unprognostic (3.14e-2)" "unprognostic (9.06e-3)" "potential prognostic unfavorable (3.64e-6)" "unprognostic (7.71e-3)" "unprognostic (2.16e-2)" "unprognostic (1.38e-2)" "unprognostic (1.68e-1)" "unprognostic (1.37e-1)" "unprognostic (2.22e-1)" "unprognostic (2.62e-2)" "unprognostic (1.13e-1)" "unprognostic (5.90e-2)" "unprognostic (3.38e-1)" PPP3CA "CALN, CALNA, CNA1, PPP2B" ENSG00000138814 "Protein phosphatase 3 catalytic subunit alpha" Q08209 4 101023409-101348278 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase, Protein phosphatase" "Craniosynostosis, Disease variant, Dwarfism, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 144.7" "Cell type enhanced" "Detected in all" "Brain excitatory neurons: 1219.9;Brain inhibitory neurons: 1380.6;Neutrophils: 2460.1;Prostatic glandular cells: 2545.2" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 6 "Prostate Adenocarcinoma (TCGA): 164.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "prostate cancer: 144.0" "Adrenal gland - Adrenal cortex cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012778, CAB018581, HPA074370" Enhanced Supported Nucleoplasm,Cytosol,Calyx NA NA 80000 "Cluster 35: Neutrophils - Protein binding" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" 31 Cytosol "Nucleoplasm, Calyx" "CAB018581: , HPA012778: , HPA074370: " "unprognostic (1.43e-2)" "unprognostic (4.12e-2)" "unprognostic (3.94e-2)" "unprognostic (3.18e-2)" "unprognostic (1.19e-1)" "unprognostic (2.25e-1)" "unprognostic (1.78e-1)" "unprognostic (2.51e-2)" "unprognostic (4.45e-2)" "unprognostic (2.28e-2)" "potential prognostic favorable (1.55e-5)" "unprognostic (2.46e-3)" "unprognostic (1.40e-1)" "unprognostic (9.31e-3)" "unprognostic (4.09e-1)" "unprognostic (6.25e-3)" "unprognostic (1.85e-3)" "unprognostic (2.63e-1)" "unprognostic (7.15e-3)" "unprognostic (2.73e-3)" "potential prognostic unfavorable (1.53e-4)" "potential prognostic unfavorable (7.34e-4)" "unprognostic (9.13e-3)" "unprognostic (1.08e-1)" "unprognostic (8.85e-2)" "unprognostic (8.62e-2)" "unprognostic (2.89e-2)" "unprognostic (1.53e-1)" "unprognostic (1.24e-1)" "unprognostic (2.82e-2)" "unprognostic (1.85e-1)" PPP3CB "CALNA2, CALNB, CNA2, PP2Bbeta" ENSG00000107758 "Protein phosphatase 3 catalytic subunit beta" P16298 10 73436433-73496024 "Enzymes, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 355.5" "Cell type enhanced" "Detected in all" "Myonuclei: 417.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Endothelial cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008233, HPA074370" Uncertain Supported Nucleoplasm,Cytosol,Calyx NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 14: Neurons - Synaptic function" "Cluster 52: Non-specific - Mitochondria" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 21 Cytosol "Nucleoplasm, Calyx" "HPA008233: , HPA074370: " "unprognostic (2.95e-2)" "unprognostic (6.59e-2)" "unprognostic (2.79e-1)" "unprognostic (6.36e-2)" "unprognostic (1.87e-1)" "unprognostic (9.65e-2)" "unprognostic (1.30e-1)" "potential prognostic favorable (1.65e-4)" "unprognostic (3.07e-2)" "unprognostic (2.20e-1)" "potential prognostic favorable (3.83e-5)" "unprognostic (5.55e-2)" "unprognostic (4.39e-2)" "unprognostic (2.29e-3)" "unprognostic (1.55e-1)" "unprognostic (8.37e-2)" "unprognostic (1.27e-2)" "unprognostic (1.26e-1)" "unprognostic (6.34e-2)" "unprognostic (1.19e-1)" "unprognostic (4.32e-3)" "unprognostic (1.77e-3)" "unprognostic (1.16e-2)" "unprognostic (2.18e-1)" "unprognostic (1.41e-1)" "unprognostic (2.81e-2)" "unprognostic (1.26e-1)" "unprognostic (1.93e-1)" "unprognostic (1.70e-1)" "unprognostic (8.45e-2)" "unprognostic (8.17e-2)" PPP3CC "CALNA3, PP2Bgamma" ENSG00000120910 "Protein phosphatase 3 catalytic subunit gamma" P48454 8 22440819-22541142 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 490.1;Cone photoreceptor cells: 428.5;Myonuclei: 778.4;Rod photoreceptor cells: 461.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023396, CAB024950, HPA074370" Approved Approved Nucleoplasm,Cytosol,Calyx NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 16: Non-specific - Transcription" "Cluster 6: Leukemia - Signal transduction" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 13 Cytosol "Nucleoplasm, Calyx" "CAB024950: , HPA023396: , HPA074370: " "potential prognostic favorable (4.06e-4)" "unprognostic (1.91e-1)" "unprognostic (4.76e-3)" "unprognostic (3.53e-1)" "unprognostic (8.43e-2)" "unprognostic (8.36e-2)" "unprognostic (2.09e-1)" "unprognostic (1.61e-3)" "unprognostic (6.58e-3)" "unprognostic (2.95e-1)" "validated prognostic favorable (6.65e-4)" "validated prognostic favorable (5.01e-4)" "unprognostic (1.54e-1)" "unprognostic (1.66e-2)" "potential prognostic favorable (2.33e-4)" "unprognostic (1.22e-2)" "unprognostic (9.01e-2)" "unprognostic (1.60e-2)" "unprognostic (3.90e-2)" "unprognostic (3.67e-3)" "unprognostic (1.88e-2)" "unprognostic (1.29e-1)" "unprognostic (1.95e-2)" "unprognostic (4.08e-2)" "unprognostic (1.71e-1)" "unprognostic (1.62e-3)" "unprognostic (6.35e-2)" "unprognostic (5.65e-2)" "unprognostic (2.67e-1)" "unprognostic (1.17e-1)" "unprognostic (2.38e-1)" PPP3R1 "CALNB1, CNB, CNB1" ENSG00000221823 "Protein phosphatase 3 regulatory subunit B, alpha" P63098 2 68178857-68256237 "FDA approved drug targets, Predicted intracellular proteins" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 153.9;retina: 175.8" "Cell type enhanced" "Detected in many" "Early spermatids: 12.0;Late primary spermatocytes: 7.2;Megakaryocyte progenitors: 8.7;Megakaryocytes: 24.7;Platelets: 18.2;Rod photoreceptor cells: 8.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.7" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005610, HPA047157" Approved Supported "Plasma membrane,Primary cilium,Cytosol" NA NA 53000 "Cluster 35: Neutrophils - Protein binding" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 47: Platelets - Hemostasis" 21 "Plasma membrane" "Primary cilium, Cytosol" "CAB005610: , HPA047157: " "unprognostic (2.60e-2)" "unprognostic (1.17e-2)" "unprognostic (2.40e-1)" "unprognostic (3.51e-2)" "unprognostic (1.14e-1)" "unprognostic (5.23e-3)" "unprognostic (2.84e-1)" "unprognostic (7.49e-3)" "unprognostic (2.20e-1)" "unprognostic (1.66e-3)" "potential prognostic favorable (2.48e-5)" "unprognostic (6.02e-2)" "potential prognostic unfavorable (3.65e-4)" "unprognostic (6.85e-2)" "unprognostic (2.52e-2)" "unprognostic (1.35e-1)" "unprognostic (3.97e-2)" "unprognostic (1.43e-1)" "unprognostic (5.47e-2)" "unprognostic (7.72e-2)" "unprognostic (4.43e-2)" "potential prognostic unfavorable (6.20e-4)" "unprognostic (1.40e-2)" "unprognostic (9.26e-2)" "unprognostic (2.19e-1)" "unprognostic (3.13e-2)" "unprognostic (1.31e-1)" "unprognostic (1.01e-1)" "unprognostic (2.95e-1)" "unprognostic (7.52e-3)" "unprognostic (3.02e-1)" PPP3R2 PPP3RL ENSG00000188386 "Protein phosphatase 3 regulatory subunit B, beta" Q96LZ3 9 101591604-101595021 "FDA approved drug targets, Predicted intracellular proteins" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 619 "testis: 76.0" "Group enriched" "Detected in some" 8 "Early spermatids: 1.5;Late primary spermatocytes: 3.8;Late spermatids: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" HPA047157 Uncertain Approved "Plasma membrane,Primary cilium,Cytosol" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 24: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 7 "Plasma membrane" "Primary cilium, Cytosol" "HPA047157: " PPP4C "PP4, PPX" ENSG00000149923 "Protein phosphatase 4 catalytic subunit" P60510 16 30075978-30085376 "Enzymes, Essential proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 358.5;Esophageal apical cells: 677.9;Esophageal suprabasal cells: 328.6;Extravillous trophoblasts: 417.3;Migrating cytotrophoblasts: 366.7;Oocytes: 340.8;Syncytiotrophoblasts: 497.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043837 Supported Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 93 Nucleoplasm "Plasma membrane, Cytosol" "HPA043837: " "unprognostic (1.04e-2)" "potential prognostic unfavorable (9.40e-4)" "unprognostic (3.33e-1)" "unprognostic (5.19e-2)" "unprognostic (2.60e-1)" "unprognostic (1.52e-1)" "unprognostic (3.94e-1)" "unprognostic (3.57e-2)" "unprognostic (1.15e-2)" "unprognostic (3.40e-1)" "unprognostic (2.99e-1)" "unprognostic (1.31e-3)" "unprognostic (1.43e-1)" "validated prognostic unfavorable (4.87e-4)" "validated prognostic unfavorable (4.12e-4)" "potential prognostic unfavorable (9.74e-4)" "unprognostic (5.17e-3)" "unprognostic (1.26e-1)" "unprognostic (1.90e-1)" "unprognostic (4.08e-2)" "unprognostic (1.63e-1)" "unprognostic (3.03e-2)" "unprognostic (1.26e-1)" "unprognostic (5.37e-2)" "unprognostic (1.09e-1)" "unprognostic (4.33e-1)" "unprognostic (2.10e-1)" "unprognostic (3.49e-1)" "unprognostic (1.79e-1)" "unprognostic (1.12e-1)" "unprognostic (7.01e-3)" PPP4R1 PP4R1 ENSG00000154845 "Protein phosphatase 4 regulatory subunit 1" Q8TF05 18 9546791-9615240 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 395.3;Esophageal apical cells: 724.6;Neutrophils: 524.4;Urothelial cells: 351.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 36.2" "Lineage enriched" "Detected in all" 5 "granulocytes: 36.2" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040905, HPA041089" Uncertain Approved "Plasma membrane,Actin filaments,Cytosol,Perinuclear theca,Calyx,Mid piece,Principal piece,End piece" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 13: Non-specific - Mixed function" "Cluster 24: Neutrophils - Innate immunity signal integration" 14 "Plasma membrane, Cytosol" "Actin filaments, Perinuclear theca, Calyx, Mid piece, Principal piece, End piece" "HPA040905: , HPA041089: " "unprognostic (5.12e-2)" "unprognostic (3.55e-2)" "unprognostic (2.94e-1)" "unprognostic (4.13e-2)" "unprognostic (3.46e-2)" "unprognostic (1.87e-3)" "unprognostic (9.19e-2)" "unprognostic (7.57e-3)" "unprognostic (2.21e-1)" "unprognostic (4.92e-2)" "potential prognostic favorable (1.23e-5)" "unprognostic (4.24e-3)" "unprognostic (2.05e-1)" "unprognostic (3.23e-3)" "unprognostic (1.04e-3)" "unprognostic (4.84e-2)" "unprognostic (1.87e-1)" "unprognostic (7.26e-2)" "unprognostic (2.41e-1)" "unprognostic (9.11e-2)" "unprognostic (7.64e-2)" "unprognostic (2.64e-2)" "unprognostic (1.05e-3)" "unprognostic (3.15e-1)" "unprognostic (1.41e-1)" "unprognostic (1.48e-1)" "unprognostic (4.78e-2)" "unprognostic (3.93e-2)" "unprognostic (3.10e-1)" "unprognostic (2.66e-1)" "unprognostic (1.77e-1)" PPP4R2 ENSG00000163605 "Protein phosphatase 4 regulatory subunit 2" Q9NY27 3 72996803-73069198 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 1114.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034695, HPA039837, HPA073758" Approved Enhanced Nucleoplasm NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 11: White matter - Signal transduction" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 57 Nucleoplasm "HPA034695: , HPA039837: , HPA073758: " "unprognostic (1.75e-1)" "unprognostic (1.77e-1)" "unprognostic (8.00e-2)" "unprognostic (2.95e-1)" "unprognostic (9.33e-2)" "unprognostic (2.78e-1)" "unprognostic (1.02e-1)" "unprognostic (1.44e-1)" "unprognostic (9.79e-3)" "unprognostic (4.35e-3)" "potential prognostic favorable (2.53e-4)" "unprognostic (1.18e-1)" "unprognostic (8.16e-2)" "unprognostic (1.96e-1)" "unprognostic (3.92e-2)" "unprognostic (5.80e-2)" "unprognostic (2.90e-3)" "unprognostic (1.56e-1)" "unprognostic (3.01e-1)" "unprognostic (2.14e-2)" "unprognostic (4.19e-2)" "unprognostic (4.05e-3)" "unprognostic (2.81e-3)" "unprognostic (2.34e-3)" "unprognostic (4.75e-3)" "unprognostic (5.44e-2)" "unprognostic (1.67e-1)" "unprognostic (2.22e-2)" "unprognostic (8.74e-2)" "unprognostic (2.18e-2)" "unprognostic (1.65e-1)" PPP4R3A "FLFL1, FLJ20707, KIAA2010, MSTP033, PP4R3, SMEK1, smk-1, smk1" ENSG00000100796 "Protein phosphatase 4 regulatory subunit 3A" Q6IN85 14 91457508-91510554 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002568, HPA063917" Approved Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 15: Bone marrow - Innate immune response" "Cluster 55: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 31 Nucleoplasm "Nuclear speckles, Cytosol" "HPA002568: , HPA063917: " "unprognostic (1.36e-1)" "unprognostic (1.29e-1)" "unprognostic (8.71e-2)" "unprognostic (7.66e-2)" "unprognostic (1.42e-1)" "unprognostic (9.29e-3)" "unprognostic (1.70e-1)" "unprognostic (1.59e-2)" "unprognostic (3.30e-1)" "unprognostic (1.15e-3)" "unprognostic (1.21e-3)" "unprognostic (1.32e-1)" "unprognostic (2.58e-2)" "unprognostic (7.18e-2)" "unprognostic (5.90e-2)" "unprognostic (4.95e-2)" "unprognostic (3.16e-2)" "unprognostic (2.09e-1)" "unprognostic (2.53e-2)" "unprognostic (1.20e-1)" "unprognostic (2.77e-2)" "unprognostic (4.90e-3)" "unprognostic (1.91e-1)" "unprognostic (6.95e-2)" "unprognostic (3.67e-2)" "unprognostic (3.42e-1)" "unprognostic (3.88e-1)" "unprognostic (6.35e-2)" "unprognostic (1.66e-1)" PPP4R3B "FLFL2, FLJ31474, KIAA1387, PSY2, SMEK2" ENSG00000275052 "Protein phosphatase 4 regulatory subunit 3B" Q5MIZ7 2 55547292-55618880 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001233, CAB017185" Approved Supported "Nucleoplasm,Nuclear speckles,Centrosome" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 7: Non-specific - Transcription" 8 "Nucleoplasm, Nuclear speckles" Centrosome "CAB017185: , HPA001233: " "unprognostic (2.15e-1)" "unprognostic (1.62e-2)" "unprognostic (2.07e-2)" "unprognostic (9.67e-2)" "unprognostic (3.84e-1)" "unprognostic (5.27e-2)" "unprognostic (2.23e-1)" "unprognostic (3.23e-2)" "potential prognostic favorable (2.95e-8)" "unprognostic (4.72e-3)" "unprognostic (2.80e-3)" "unprognostic (6.16e-2)" "unprognostic (3.72e-2)" "unprognostic (3.02e-1)" "unprognostic (3.20e-3)" "unprognostic (2.75e-2)" "unprognostic (1.37e-1)" "unprognostic (5.52e-3)" "unprognostic (8.61e-2)" "unprognostic (2.33e-2)" "unprognostic (2.26e-2)" "unprognostic (3.39e-2)" "unprognostic (8.76e-2)" "unprognostic (4.50e-1)" "unprognostic (4.53e-2)" "unprognostic (2.66e-1)" PPP4R3C "FLFL3P, FLJ32867, PPP4R3CP, SMEK3P, smk1" ENSG00000224960 "Protein phosphatase 4 regulatory subunit 3C" Q6ZMV5 X 27460207-27463341 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 9 "testis: 1.8" "Group enriched" "Detected in some" 11 "Differentiating spermatogonia: 10.2;Early primary spermatocytes: 18.3;Undifferentiated spermatogonia: 8.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Testicular Germ Cell Tumor (TCGA): 1.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 1.5;Sarcoma: 1.3" "Testis - Spermatocytes, Testis - Spermatogonia" "Not detected" "Not detected" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 106: Spermatogonia - Spermatogonial differentiation" "unprognostic (1.26e-1)" PPP4R4 "CFAP14, KIAA1622, PP4R4" ENSG00000119698 "Protein phosphatase 4 regulatory subunit 4" Q6NUP7 14 94146128-94279734 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 15.1;testis: 7.5" "Group enriched" "Detected in some" 4 "Astrocytes: 79.6;Bergmann glia: 57.3;Brain excitatory neurons: 103.1;Brain inhibitory neurons: 128.9;Ependymal cells: 33.1;Oligodendrocyte progenitor cells: 35.4;Other brain neurons: 78.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 9.6" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041866, HPA050321" Approved Supported "Primary cilium,Basal body,Cytosol" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Neurons - Synaptic function & neurogenesis" 7 Cytosol "Primary cilium, Basal body" "HPA041866: , HPA050321: " "unprognostic (4.67e-2)" "unprognostic (1.11e-1)" "unprognostic (2.68e-1)" "unprognostic (6.41e-3)" "unprognostic (2.52e-1)" "unprognostic (2.85e-3)" "unprognostic (9.18e-2)" "unprognostic (6.70e-2)" "unprognostic (2.12e-1)" "unprognostic (5.54e-2)" PPP5C "PP5, PPP5" ENSG00000011485 "Protein phosphatase 5 catalytic subunit" P53041 19 46347087-46392981 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "Hydrolase, Protein phosphatase" "Alzheimer disease, Amyloidosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022641, HPA029065, HPA056933" Approved Supported Vesicles,Cytosol NA NA 220000 "Cluster 14: Non-specific - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 4: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 62 "Vesicles, Cytosol" "CAB022641: , HPA029065: , HPA056933: " "unprognostic (2.20e-1)" "unprognostic (6.19e-3)" "unprognostic (3.96e-2)" "unprognostic (1.83e-1)" "potential prognostic favorable (7.49e-4)" "unprognostic (1.17e-1)" "unprognostic (3.40e-1)" "unprognostic (1.71e-1)" "unprognostic (6.76e-2)" "unprognostic (1.61e-1)" "potential prognostic favorable (8.55e-5)" "unprognostic (3.25e-2)" "unprognostic (3.64e-2)" "potential prognostic unfavorable (1.55e-5)" "unprognostic (1.49e-2)" "unprognostic (1.58e-2)" "unprognostic (5.55e-2)" "unprognostic (6.85e-2)" "unprognostic (2.71e-1)" "unprognostic (1.01e-1)" "unprognostic (2.28e-1)" "unprognostic (9.19e-2)" "unprognostic (2.57e-2)" "unprognostic (4.95e-2)" "unprognostic (1.92e-1)" "unprognostic (1.54e-1)" "potential prognostic unfavorable (6.71e-4)" "unprognostic (3.18e-2)" "unprognostic (1.59e-1)" "unprognostic (6.13e-2)" "unprognostic (1.49e-1)" PPP6C PP6 ENSG00000119414 "Protein phosphatase 6 catalytic subunit" O00743 9 125146573-125189939 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Cell cycle, Immunity, Innate immunity" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050940 Uncertain NA NA 170000 "Cluster 35: Neutrophils - Protein binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 59 "HPA050940: " "unprognostic (6.28e-2)" "unprognostic (6.75e-3)" "unprognostic (1.41e-2)" "unprognostic (3.69e-1)" "unprognostic (3.08e-1)" "unprognostic (5.74e-3)" "unprognostic (7.96e-2)" "unprognostic (1.81e-1)" "unprognostic (1.22e-1)" "unprognostic (7.51e-3)" "potential prognostic favorable (5.81e-8)" "unprognostic (2.35e-3)" "unprognostic (6.55e-2)" "unprognostic (2.60e-3)" "unprognostic (4.28e-3)" "unprognostic (3.97e-1)" "unprognostic (5.07e-2)" "unprognostic (5.37e-2)" "unprognostic (5.82e-2)" "unprognostic (2.79e-1)" "unprognostic (2.21e-1)" "unprognostic (3.09e-1)" "unprognostic (3.75e-1)" "unprognostic (2.05e-1)" "unprognostic (5.20e-2)" "unprognostic (2.13e-2)" "unprognostic (9.98e-2)" "unprognostic (1.08e-1)" "unprognostic (2.10e-1)" "unprognostic (2.00e-2)" "unprognostic (4.69e-2)" PPP6R1 "KIAA1115, SAP190, SAPS1" ENSG00000105063 "Protein phosphatase 6 regulatory subunit 1" Q9UPN7 19 55229779-55259017 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 236.7;Late primary spermatocytes: 87.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 28.6" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - B-cells (Spleen), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043989, HPA063681" Approved Enhanced Cytosol No No 6200 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 51: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 50 Cytosol "HPA043989: , HPA063681: " "unprognostic (8.93e-2)" "unprognostic (3.15e-2)" "unprognostic (5.93e-3)" "unprognostic (3.35e-1)" "unprognostic (6.69e-2)" "unprognostic (2.77e-1)" "unprognostic (9.78e-2)" "unprognostic (1.65e-1)" "unprognostic (1.38e-1)" "unprognostic (2.21e-2)" "unprognostic (1.16e-1)" "unprognostic (4.07e-1)" "potential prognostic unfavorable (6.84e-5)" "unprognostic (7.06e-2)" "unprognostic (3.35e-2)" "unprognostic (2.29e-1)" "unprognostic (9.97e-2)" "unprognostic (1.45e-1)" "unprognostic (1.04e-1)" "unprognostic (6.31e-2)" "unprognostic (6.26e-3)" "unprognostic (3.28e-1)" "unprognostic (9.21e-3)" "unprognostic (1.79e-1)" "unprognostic (2.94e-2)" "unprognostic (4.16e-1)" "unprognostic (1.25e-1)" "unprognostic (1.44e-1)" "unprognostic (1.07e-2)" "unprognostic (1.33e-1)" PPP6R2 "dJ579N16.1, KIAA0685, SAP190, SAPS2" ENSG00000100239 "Protein phosphatase 6 regulatory subunit 2" O75170 22 50343304-50445090 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030656, HPA075438" Approved Supported "Cytosol,Cytoplasmic bodies" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 24: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 7: Non-specific - Transcription" 22 Cytosol "Cytoplasmic bodies" "HPA030656: , HPA075438: " "unprognostic (1.24e-1)" "unprognostic (4.60e-2)" "unprognostic (2.80e-1)" "unprognostic (1.02e-1)" "unprognostic (7.19e-2)" "unprognostic (3.11e-1)" "unprognostic (1.92e-2)" "unprognostic (1.38e-2)" "unprognostic (1.45e-1)" "unprognostic (3.44e-3)" "unprognostic (3.17e-2)" "potential prognostic favorable (1.99e-4)" "unprognostic (2.78e-1)" "unprognostic (1.35e-1)" "unprognostic (5.61e-3)" "unprognostic (2.23e-1)" "unprognostic (2.86e-1)" "unprognostic (1.81e-1)" "unprognostic (8.69e-3)" "unprognostic (2.92e-2)" "unprognostic (4.33e-3)" "unprognostic (9.47e-2)" "unprognostic (1.19e-1)" "unprognostic (1.80e-1)" "unprognostic (1.44e-2)" "unprognostic (3.35e-1)" "unprognostic (8.21e-2)" "unprognostic (2.22e-1)" "unprognostic (2.25e-1)" "unprognostic (8.82e-3)" PPP6R3 "C11orf23, DKFZp781E17107, DKFZp781E2374, DKFZp781O2362, FLJ11058, FLJ43065, KIAA1558, MGC125711, MGC125712, PP6R3, SAP190, SAPL, SAPLa, SAPS3" ENSG00000110075 "Protein phosphatase 6 regulatory subunit 3" Q5H9R7 11 68460731-68615334 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017183, HPA038467, HPA038468" Supported Enhanced "Nucleoplasm,Plasma membrane,Cytosol" NA NA 3500 "Cluster 5: Non-specific - Cell proliferation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 30 "Nucleoplasm, Plasma membrane, Cytosol" "CAB017183: , HPA038467: , HPA038468: " "unprognostic (2.17e-1)" "unprognostic (1.53e-2)" "unprognostic (2.47e-3)" "unprognostic (7.65e-2)" "unprognostic (7.41e-2)" "unprognostic (6.66e-2)" "potential prognostic favorable (2.66e-4)" "unprognostic (6.32e-2)" "unprognostic (5.57e-3)" "potential prognostic favorable (1.90e-4)" "unprognostic (4.21e-3)" "unprognostic (6.52e-3)" "unprognostic (5.64e-2)" "unprognostic (1.97e-1)" "unprognostic (1.84e-2)" "potential prognostic unfavorable (1.06e-4)" "unprognostic (8.80e-2)" "unprognostic (2.39e-2)" "unprognostic (5.90e-3)" "unprognostic (5.79e-3)" "unprognostic (2.12e-2)" "potential prognostic unfavorable (3.46e-4)" "unprognostic (6.96e-2)" "unprognostic (1.57e-2)" "unprognostic (7.58e-3)" "unprognostic (1.04e-1)" "unprognostic (2.96e-1)" "unprognostic (1.05e-1)" "unprognostic (9.56e-2)" "potential prognostic unfavorable (4.06e-4)" PPRC1 "KIAA0595, MGC74642, PRC" ENSG00000148840 "PPARG related coactivator 1" Q5VV67 10 102132994-102150333 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epicardial cells: 131.9;Ocular epithelial cells: 87.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038511, HPA057571" Approved Enhanced Nucleoplasm NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 24: Non-specific - Transcription" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 52: Non-specific - Mitochondria" "Cluster 103: Non-specific - Basic cellular processes" Nucleoplasm "HPA038511: , HPA057571: " "unprognostic (2.64e-1)" "unprognostic (2.07e-1)" "unprognostic (3.78e-1)" "unprognostic (2.30e-1)" "unprognostic (1.01e-2)" "unprognostic (5.15e-2)" "unprognostic (4.09e-1)" "unprognostic (4.20e-3)" "unprognostic (9.09e-2)" "unprognostic (3.32e-1)" "unprognostic (1.06e-2)" "unprognostic (6.59e-2)" "unprognostic (2.99e-3)" "unprognostic (2.63e-3)" "unprognostic (4.83e-3)" "unprognostic (9.13e-2)" "potential prognostic unfavorable (3.77e-4)" "unprognostic (8.49e-2)" "unprognostic (6.46e-2)" "unprognostic (2.91e-1)" "unprognostic (2.95e-3)" "unprognostic (1.68e-1)" "potential prognostic unfavorable (9.84e-4)" "unprognostic (1.86e-1)" "unprognostic (1.21e-1)" "unprognostic (1.20e-2)" "unprognostic (4.11e-2)" "unprognostic (2.89e-1)" "unprognostic (1.52e-1)" "unprognostic (4.90e-2)" "unprognostic (8.26e-2)" PPT1 "CLN1, INCL, PPT" ENSG00000131238 "Palmitoyl-protein thioesterase 1" P50897 1 40072710-40097260 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" Hydrolase "Disease variant, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "cDC: 244.6;Kupffer cells: 549.4;Macrophages: 196.8;Monocyte progenitors: 173.1;monocytes: 206.4;Neutrophils: 312.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 1254.9;eosinophil: 625.5;intermediate monocyte: 1006.3;myeloid DC: 1091.1;neutrophil: 685.3;non-classical monocyte: 818.8" "Group enriched" "Detected in all" 4 "dendritic cells: 1091.1;granulocytes: 685.3;monocytes: 1254.9" "Low cancer specificity" "Detected in all" "Lung - Macrophages, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021546 Supported Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" Enzyme NA NA 260000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 21: Non-specific - Metabolism" "Cluster 27: Breast cancer - Unknown function" "Cluster 82: Dendritic cells - Antigen presentation" 31 "Golgi apparatus, Vesicles" "HPA021546: " "unprognostic (6.03e-2)" "unprognostic (2.06e-2)" "unprognostic (1.11e-2)" "unprognostic (2.08e-1)" "unprognostic (7.15e-2)" "unprognostic (5.57e-3)" "unprognostic (1.32e-1)" "unprognostic (2.44e-1)" "unprognostic (8.50e-2)" "unprognostic (5.53e-2)" "potential prognostic favorable (1.27e-8)" "unprognostic (5.56e-2)" "unprognostic (5.80e-2)" "potential prognostic unfavorable (3.26e-9)" "unprognostic (1.11e-3)" "unprognostic (6.76e-2)" "unprognostic (3.13e-2)" "unprognostic (1.32e-1)" "unprognostic (1.46e-1)" "unprognostic (3.42e-2)" "unprognostic (6.99e-2)" "unprognostic (1.65e-1)" "unprognostic (2.95e-1)" "unprognostic (1.12e-1)" "unprognostic (2.67e-1)" "unprognostic (1.28e-2)" "unprognostic (1.13e-1)" "unprognostic (7.67e-2)" "unprognostic (1.99e-1)" "unprognostic (7.61e-2)" "unprognostic (1.42e-1)" PPT2 ENSG00000221988 "Palmitoyl-protein thioesterase 2" Q9UMR5 6 32153441-32163678 "Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 5.7;Bergmann glia: 6.9;Brain excitatory neurons: 6.7;Brain inhibitory neurons: 5.7;Choroid plexus epithelial cells: 5.4;Ependymal cells: 6.9;Microglia: 1.8;Oligodendrocyte progenitor cells: 7.2;Oligodendrocytes: 7.1;Other brain neurons: 5.9" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 21.1" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "naive CD8 T-cell: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000559, HPA001057" Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" Enzyme NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 64: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 104: Brain endothelial cells - Blood brain barrier" "Golgi apparatus, Vesicles" "HPA000559: , HPA001057: " "unprognostic (1.09e-2)" "unprognostic (2.20e-1)" "unprognostic (1.38e-1)" "unprognostic (1.96e-1)" "unprognostic (6.48e-2)" "unprognostic (4.91e-1)" "unprognostic (3.32e-2)" "unprognostic (2.53e-3)" "unprognostic (1.06e-1)" "unprognostic (1.61e-1)" "unprognostic (1.49e-1)" "unprognostic (4.19e-1)" "unprognostic (5.21e-2)" "unprognostic (8.53e-2)" "unprognostic (3.05e-2)" "unprognostic (1.17e-1)" "unprognostic (8.15e-2)" "unprognostic (6.23e-2)" "unprognostic (5.71e-2)" "unprognostic (1.41e-1)" "unprognostic (2.39e-1)" "unprognostic (1.04e-1)" "unprognostic (1.47e-2)" "unprognostic (3.54e-2)" "unprognostic (3.33e-1)" "unprognostic (1.41e-1)" "unprognostic (1.46e-2)" "unprognostic (1.44e-1)" "unprognostic (3.22e-1)" "unprognostic (1.15e-1)" PPTC7 TA-PP2C ENSG00000196850 "Protein phosphatase targeting COQ7" Q8NI37 12 110533245-110583318 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 130.9" "Cell type enhanced" "Detected in many" "Myonuclei: 319.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039335, HPA040614" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 45: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 27 "Plasma membrane, Cytosol" "HPA039335: , HPA040614: " "unprognostic (1.07e-1)" "unprognostic (1.61e-1)" "unprognostic (1.43e-1)" "unprognostic (1.38e-1)" "unprognostic (9.85e-2)" "unprognostic (3.14e-2)" "unprognostic (2.13e-1)" "unprognostic (4.35e-1)" "unprognostic (1.30e-1)" "unprognostic (3.99e-2)" "potential prognostic favorable (3.48e-6)" "unprognostic (3.29e-2)" "unprognostic (1.22e-2)" "unprognostic (4.17e-1)" "unprognostic (5.03e-1)" "unprognostic (7.41e-3)" "unprognostic (2.00e-3)" "unprognostic (2.64e-1)" "unprognostic (1.53e-1)" "potential prognostic unfavorable (8.58e-4)" "unprognostic (9.20e-3)" "potential prognostic unfavorable (1.10e-4)" "unprognostic (6.89e-3)" "unprognostic (1.27e-1)" "unprognostic (2.97e-2)" "unprognostic (3.04e-3)" "unprognostic (3.05e-1)" "unprognostic (1.33e-1)" "unprognostic (2.66e-1)" "unprognostic (1.94e-3)" "unprognostic (2.44e-1)" PPWD1 KIAA0073 ENSG00000113593 "Peptidylprolyl isomerase domain and WD repeat containing 1" Q96BP3 5 65563236-65587549 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019353, HPA019360" Enhanced Supported "Nuclear bodies" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 39: Testis - Nuclear processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 7: Non-specific - Transcription" 13 "Nuclear bodies" "HPA019353: , HPA019360: " "unprognostic (1.85e-2)" "unprognostic (2.75e-1)" "unprognostic (1.08e-1)" "unprognostic (1.09e-1)" "unprognostic (9.28e-2)" "unprognostic (2.13e-1)" "unprognostic (2.21e-1)" "unprognostic (6.20e-2)" "unprognostic (1.69e-2)" "unprognostic (2.82e-2)" "unprognostic (4.36e-3)" "unprognostic (5.03e-2)" "unprognostic (1.33e-1)" "potential prognostic unfavorable (3.52e-4)" "unprognostic (3.78e-2)" "unprognostic (7.90e-2)" "unprognostic (1.40e-1)" "unprognostic (2.24e-1)" "unprognostic (1.32e-1)" "unprognostic (4.90e-2)" "unprognostic (3.75e-2)" "unprognostic (8.80e-3)" "unprognostic (1.78e-2)" "unprognostic (4.90e-2)" "unprognostic (2.99e-3)" "unprognostic (1.64e-2)" "unprognostic (1.25e-1)" "unprognostic (1.51e-1)" "unprognostic (1.80e-1)" "unprognostic (1.50e-1)" "unprognostic (3.24e-2)" PPY PNP ENSG00000108849 "Pancreatic polypeptide" P01298 17 43940804-43942476 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" Hormone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 22 "pancreas: 152.7" "Cell type enriched" "Detected in some" 22 "Pancreatic islet cells: 1835.2" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 114 "Pancreatic Adenocarcinoma (TCGA): 2590.2" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 7 "myeloid DC: 1.2" "Lineage enriched" "Detected in single" 12 "dendritic cells: 1.2" "Cancer enhanced" "Detected in single" "Neuroblastoma: 2.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB016735, HPA032122" Enhanced "Secreted to blood" Hormone NA NA 70300 "Cluster 2: Dendritic cells - Unknown function" "Cluster 8: Pancreas - Proteolysis" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 5 "CAB016735: , HPA032122: " "unprognostic (8.44e-2)" "unprognostic (7.41e-3)" "unprognostic (6.73e-2)" "unprognostic (7.10e-2)" "unprognostic (2.60e-1)" "unprognostic (6.32e-3)" PQBP1 "MRX2, MRX55, MRXS3, MRXS8, RENS1, SHS" ENSG00000102103 "Polyglutamine binding protein 1" O60828 X 48890197-48903402 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Immunity, Innate immunity, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001880 Supported Supported "Nucleoplasm,Nuclear speckles,Microtubules,Primary cilium,Basal body,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 54: Non-specific - Ribosome" "Cluster 45: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 15: Non-specific - Protein processing" 31 "Nucleoplasm, Nuclear speckles, Primary cilium" "Microtubules, Basal body, Cytosol" "HPA001880: " "unprognostic (3.70e-1)" "unprognostic (8.43e-2)" "unprognostic (1.06e-1)" "unprognostic (1.73e-1)" "unprognostic (1.20e-1)" "unprognostic (3.39e-2)" "unprognostic (3.63e-2)" "potential prognostic favorable (6.70e-4)" "unprognostic (1.34e-2)" "unprognostic (1.92e-1)" "unprognostic (2.30e-3)" "unprognostic (1.36e-3)" "unprognostic (1.51e-2)" "unprognostic (2.14e-2)" "potential prognostic unfavorable (8.26e-4)" "unprognostic (1.93e-1)" "unprognostic (9.40e-2)" "unprognostic (1.76e-1)" "unprognostic (1.36e-1)" "unprognostic (5.93e-2)" "unprognostic (3.56e-2)" "unprognostic (7.54e-2)" "unprognostic (2.87e-1)" "unprognostic (3.42e-2)" "unprognostic (1.13e-1)" "unprognostic (6.17e-2)" "unprognostic (1.01e-1)" "unprognostic (1.92e-1)" "unprognostic (8.27e-2)" "unprognostic (2.40e-1)" "unprognostic (2.00e-1)" PRAC1 "C17orf92, PRAC" ENSG00000159182 "PRAC1 small nuclear protein" Q96KF2 17 48721719-48722518 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 11 "intestine: 192.7;prostate: 103.8" "Group enriched" "Detected in some" 5 "Colonocytes: 607.6;Enteric stem cells: 658.1;Enteric transient amplifying cells: 553.2;Goblet cells: 595.6;Neuroendocrine cells: 397.4;Prostatic glandular cells: 180.9" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "Prostate Adenocarcinoma (TCGA): 689.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "prostate cancer: 459.9" "Prostate - Prostate glandular cells" HPA047871 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 17: Intestine - Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" Nucleoplasm Cytosol "HPA047871: " "unprognostic (1.57e-2)" "unprognostic (1.14e-1)" "unprognostic (1.91e-1)" "unprognostic (7.07e-2)" "unprognostic (1.35e-1)" "unprognostic (5.72e-1)" "unprognostic (6.23e-2)" "unprognostic (5.81e-2)" "unprognostic (9.83e-3)" "unprognostic (1.50e-1)" PRAC2 "C17orf93, HOXB-AS5, HOXB13-AS1, NCRNA00253" ENSG00000229637 "PRAC2 small nuclear protein" D3DTV9 17 48723185-48724758 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 4 "intestine: 9.0;prostate: 13.4" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 10.5;Colonocytes: 22.1;Early spermatids: 42.1;Enteric stem cells: 21.4;Enteric transient amplifying cells: 53.3;Goblet cells: 16.3;Late spermatids: 73.7;Neuroendocrine cells: 15.7;Prostatic club cells: 15.0;Prostatic glandular cells: 25.4;Prostatic hillock cells: 11.1;Tuft cells: 11.5;Urothelial cells: 9.9" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 8 "Prostate Adenocarcinoma (TCGA): 61.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Bone cancer: 16.3;prostate cancer: 44.6" "Prostate - Prostate glandular cells, Testis - Late spermatids" "Intracellular and membrane" "No annotated function" NA NA "Cluster 77: Intestine - Digestion" "Cluster 60: Prostate cancer - Unknown function" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" "potential prognostic unfavorable (1.73e-4)" "unprognostic (4.38e-3)" "unprognostic (8.75e-3)" "unprognostic (1.53e-1)" "unprognostic (1.65e-1)" "unprognostic (4.69e-2)" "unprognostic (9.87e-2)" "unprognostic (4.23e-1)" "unprognostic (2.80e-2)" "unprognostic (2.00e-1)" "unprognostic (5.40e-2)" "unprognostic (4.24e-1)" "unprognostic (1.33e-1)" "unprognostic (2.32e-1)" "unprognostic (7.43e-2)" PRADC1 "C2orf7, hPAP21, MGC13004, PAP21" ENSG00000135617 "Protease associated domain containing 1" Q9BSG0 2 73228010-73233239 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 118.7" "Cell type enhanced" "Detected in many" "Enterocytes: 87.5;Esophageal suprabasal cells: 84.2;Late primary spermatocytes: 141.3;Late spermatids: 256.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051066 Approved "Secreted to blood" "No annotated function" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 7: Liver cancer - Metabolism" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 1 "HPA051066: " "unprognostic (3.21e-1)" "unprognostic (5.01e-2)" "unprognostic (6.23e-2)" "unprognostic (1.27e-1)" "unprognostic (1.03e-2)" "unprognostic (1.70e-1)" "unprognostic (2.34e-2)" "unprognostic (7.76e-2)" "unprognostic (1.23e-3)" "unprognostic (2.87e-2)" "potential prognostic unfavorable (8.07e-4)" "potential prognostic favorable (4.19e-6)" "unprognostic (2.70e-1)" "potential prognostic unfavorable (1.66e-4)" "unprognostic (1.72e-1)" "unprognostic (1.97e-1)" "unprognostic (1.86e-2)" "unprognostic (3.00e-1)" "unprognostic (2.30e-1)" "unprognostic (2.60e-1)" "unprognostic (1.14e-3)" "unprognostic (9.28e-2)" "unprognostic (4.81e-3)" "unprognostic (1.11e-2)" "unprognostic (4.74e-3)" "unprognostic (1.42e-1)" "unprognostic (7.29e-2)" "unprognostic (2.22e-1)" "unprognostic (9.93e-3)" "unprognostic (1.88e-1)" PRAF2 "JM4, Yip6a" ENSG00000243279 "PRA1 domain family member 2" O60831 X 49071161-49074002 "Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 154.3" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 155.9;Epididymal principal cells: 263.8;Hepatic stellate cells: 64.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "HPA002859, HPA005504, CAB011655" Enhanced Approved "Endoplasmic reticulum,Vesicles" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 22: Epididymis - Mixed function" "Cluster 27: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" 40 "Endoplasmic reticulum" Vesicles "CAB011655: , HPA002859: , HPA005504: " "unprognostic (4.73e-2)" "unprognostic (3.38e-2)" "unprognostic (3.66e-2)" "unprognostic (2.71e-2)" "unprognostic (4.86e-3)" "unprognostic (2.00e-2)" "unprognostic (3.59e-1)" "unprognostic (2.46e-1)" "unprognostic (2.68e-1)" "unprognostic (8.89e-3)" "unprognostic (2.60e-2)" "unprognostic (6.44e-2)" "unprognostic (5.59e-2)" "potential prognostic unfavorable (3.43e-6)" "unprognostic (1.76e-2)" "unprognostic (2.56e-2)" "unprognostic (1.26e-1)" "unprognostic (8.58e-2)" "unprognostic (2.72e-1)" "unprognostic (2.01e-1)" "unprognostic (9.86e-2)" "potential prognostic favorable (3.83e-4)" "unprognostic (3.81e-2)" "unprognostic (6.67e-3)" "unprognostic (6.07e-3)" "unprognostic (8.85e-2)" "unprognostic (1.54e-1)" "unprognostic (4.54e-2)" "unprognostic (2.11e-2)" "unprognostic (1.56e-1)" "unprognostic (2.44e-1)" PRAG1 "DKFZp761P0423, NACK, PEAK2, PRAGMIN, SgK223" ENSG00000275342 "PEAK1 related, kinase-activating pseudokinase 1" Q86YV5 8 8317736-8386439 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 41.0;thyroid gland: 22.0" "Cell type enhanced" "Detected in many" "Astrocytes: 33.3;Bergmann glia: 41.5;Brain excitatory neurons: 104.7;Brain inhibitory neurons: 56.6;Ependymal cells: 53.0;Loop of henle epithelial cells: 34.0;Microglia: 73.0;Papillary tip epithelial cells: 32.5;Proximal tubule cells: 48.4" "Cell type enhanced" "Detected in all" "upper rhombic lip: 265.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011776, HPA012066" Uncertain Uncertain "Nucleoli,Focal adhesion sites" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 6 Nucleoli "Focal adhesion sites" "HPA011776: , HPA012066: " "unprognostic (1.37e-1)" "unprognostic (1.82e-2)" "unprognostic (3.54e-1)" "unprognostic (5.06e-2)" "unprognostic (2.49e-2)" "unprognostic (2.02e-1)" "unprognostic (1.30e-1)" "unprognostic (6.72e-2)" "potential prognostic favorable (1.29e-5)" "unprognostic (4.07e-2)" "unprognostic (8.26e-2)" "unprognostic (9.56e-2)" "unprognostic (3.40e-2)" "unprognostic (5.84e-2)" "unprognostic (7.64e-2)" "unprognostic (2.14e-2)" "unprognostic (2.14e-2)" "unprognostic (5.20e-2)" "unprognostic (3.13e-1)" "unprognostic (1.62e-1)" "unprognostic (3.67e-2)" "unprognostic (9.54e-3)" "unprognostic (6.82e-2)" "unprognostic (2.71e-1)" "unprognostic (2.06e-2)" "unprognostic (1.97e-2)" PRAM1 PML-RAR ENSG00000133246 "PML-RARA regulated adaptor molecule 1" Q96QH2 19 8490056-8502640 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "bone marrow: 91.5" "Cell type enhanced" "Detected in many" "cDC: 42.2;Kupffer cells: 55.3;Macrophages: 45.1;Microglia: 107.0;Monocyte progenitors: 174.9;monocytes: 139.8;Neutrophil progenitors: 397.3;Neutrophils: 167.8;Thymocytes: 55.1" "Cell type enriched" "Detected in many" 4 "central nervous system macrophage: 134.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 95.5;intermediate monocyte: 101.3;myeloid DC: 58.7;neutrophil: 54.2;non-classical monocyte: 122.0" "Group enriched" "Detected in many" 7 "dendritic cells: 58.7;granulocytes: 54.2;monocytes: 122.0" "Cancer enriched" "Detected in single" 91 "Leukemia: 42.6" "Breast - T-cells, Spleen - Neutrophils_2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA045236, HPA050161" Approved Approved "Golgi apparatus" NA NA 4300 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 15: Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 26 "Golgi apparatus" "HPA045236: , HPA050161: " "unprognostic (2.76e-2)" "unprognostic (3.29e-2)" "unprognostic (4.64e-3)" "unprognostic (1.20e-2)" "unprognostic (7.62e-3)" "unprognostic (1.03e-1)" "unprognostic (6.12e-2)" "unprognostic (1.46e-1)" "unprognostic (1.71e-1)" "potential prognostic favorable (4.37e-4)" "unprognostic (2.15e-2)" "unprognostic (8.65e-3)" "unprognostic (1.79e-1)" "unprognostic (8.85e-2)" "unprognostic (3.14e-1)" "unprognostic (9.88e-2)" "unprognostic (1.42e-1)" "unprognostic (8.29e-2)" "unprognostic (1.56e-2)" "unprognostic (3.38e-1)" "unprognostic (2.86e-1)" "unprognostic (1.17e-2)" "unprognostic (8.78e-3)" "unprognostic (1.79e-1)" "unprognostic (1.21e-2)" PRAME "CT130, MAPE" ENSG00000185686 "PRAME nuclear receptor transcriptional regulator" P78395 22 22547701-22559361 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Differentiation, Growth regulation, Transcription, Transcription regulation, Ubl conjugation pathway" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "testis: 102.1" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 41.1;Early primary spermatocytes: 13.8;Endometrial ciliated cells: 2.9;Late primary spermatocytes: 3.6;Late spermatids: 4.7;Oocytes: 9.2;Sertoli cells: 4.0;Undifferentiated spermatogonia: 12.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 192.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 136.9" "Not detected" "Not detected" "HPA045153, HPA068562, CAB080138" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 5: Rhabdoid - Unknown function" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 27 Nucleoplasm "Plasma membrane" "CAB080138: , HPA045153: , HPA068562: " "unprognostic (2.76e-3)" "unprognostic (5.22e-3)" "unprognostic (1.11e-1)" "unprognostic (1.39e-1)" "unprognostic (4.00e-2)" "unprognostic (2.34e-2)" "unprognostic (7.12e-2)" "unprognostic (2.05e-3)" "validated prognostic unfavorable (4.96e-7)" "validated prognostic unfavorable (5.60e-4)" "unprognostic (2.60e-1)" "unprognostic (2.32e-2)" "unprognostic (5.29e-3)" "unprognostic (1.28e-2)" "unprognostic (2.07e-1)" "unprognostic (2.42e-2)" "unprognostic (2.15e-2)" "unprognostic (4.45e-3)" "unprognostic (2.65e-2)" "unprognostic (8.39e-3)" "unprognostic (2.01e-1)" "unprognostic (1.70e-1)" "unprognostic (7.60e-2)" "unprognostic (2.60e-1)" "unprognostic (1.62e-1)" "unprognostic (1.02e-2)" PRAMEF1 ENSG00000116721 "PRAME family member 1" O95521 1 12791397-12796628 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Group enriched" "Detected in some" 44 "Early spermatids: 8.6;Late primary spermatocytes: 5.0;Late spermatids: 2.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 22 "Bone cancer: 2.2" NA NA "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" PRAMEF10 ENSG00000187545 "PRAME family member 10" O60809 1 12892896-12898270 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 21 "liver: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 15 "Liver Hepatocellular Carcinoma (TCGA): 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 53: Liver - Plasma proteins" "Cluster 10: Ciliated cells - Ion channel activity" 1 "unprognostic (1.98e-1)" "unprognostic (2.05e-3)" PRAMEF11 ENSG00000239810 "PRAME family member 11" O60813 1 12824605-12831410 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" NA NA "Cluster 51: Myeloma - Immunoglobulins" PRAMEF12 ENSG00000116726 "PRAME family member 12" O95522 1 12773738-12777906 "Plasma proteins, Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045286, HPA051704" Uncertain Uncertain Nucleoplasm NA NA "Cluster 27: Breast cancer - Unknown function" Nucleoplasm "HPA045286: , HPA051704: " PRAMEF13 ENSG00000279169 "PRAME family member 13" Q5VWM6 1 13196188-13201409 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA PRAMEF14 ENSG00000204481 "PRAME family member 14" Q5SWL7 1 13341892-13347134 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 4 "Early spermatids: 8.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" NA NA "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" PRAMEF15 ENSG00000204501 "PRAME family member 15" "P0DUQ1, P0DUQ2" 1 13315581-13322598 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 9 "Liver Hepatocellular Carcinoma (TCGA): 1.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 10: Ciliated cells - Ion channel activity" "unprognostic (2.10e-1)" PRAMEF17 ENSG00000204479 "PRAME family member 17" Q5VTA0 1 13389632-13392629 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 3 PRAMEF18 ENSG00000279804 "PRAME family member 18" Q5VWM3 1 13222695-13226154 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA057423 Uncertain NA NA "HPA057423: " PRAMEF19 ENSG00000204480 "PRAME family member 19" Q5SWL8 1 13368431-13371947 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA057423 Uncertain NA NA "Cluster 48: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "HPA057423: " PRAMEF2 FLJ43580 ENSG00000120952 "PRAME family member 2" O60811 1 12857086-12861909 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" NA NA "Cluster 15: Kidney cancer - Membrane components" 5 PRAMEF20 "OTTHUMT00000008157, PRAMEF21" ENSG00000204478 "PRAME family member 20" Q5VT98 1 13410450-13421328 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 4 "Myonuclei: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 46: Skeletal myocytes - Muscle structure & formation" PRAMEF25 ENSG00000229571 "PRAME family member 25" A6NGN4 1 13068677-13077884 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA PRAMEF26 ENSG00000280267 "PRAME family member 26" 1 13148905-13158116 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 48: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" PRAMEF27 ENSG00000274764 "PRAME family member 27" A3QJZ7 1 13049476-13056575 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA PRAMEF33 PRAMEF33P ENSG00000237700 "PRAME family member 33" A0A0G2JMD5 1 13303539-13308907 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 11 "liver: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 31: Liver - Metabolism & Coagulation" PRAMEF4 RP5-845O24.6 ENSG00000243073 "PRAME family member 4" O60810 1 12879212-12886201 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "Liver Hepatocellular Carcinoma (TCGA): 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 51: Myeloma - Immunoglobulins" "unprognostic (1.62e-1)" "unprognostic (1.95e-3)" PRAMEF5 "PRAMEF23, PRAMEF5L" ENSG00000270601 "PRAME family member 5" Q5TYX0 1 13254198-13263435 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA PRAMEF6 ENSG00000232423 "PRAME family member 6" Q5VXH4 1 12938472-12947580 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA PRAMEF7 ENSG00000204510 "PRAME family member 7" Q5VXH5 1 12916610-12920751 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049887, HPA051704" Uncertain NA NA "Cluster 51: Myeloma - Immunoglobulins" "HPA049887: , HPA051704: " PRAMEF8 ENSG00000182330 "PRAME family member 8" Q5VWM4 1 13281304-13285137 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049887, HPA051704" Uncertain NA NA "Cluster 34: Testis cancer - Unknown function" "HPA049887: , HPA051704: " PRAMEF9 ENSG00000204505 "PRAME family member 9" 1 13171848-13179459 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 52 "skeletal muscle: 31.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "prostate cancer: 1.2" NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 10: Ciliated cells - Ion channel activity" PRAP1 UPA ENSG00000165828 "Proline rich acidic protein 1" Q96NZ9 10 133347368-133352683 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 1069.3;liver: 718.1" "Cell type enriched" "Detected in some" 16 "Enterocytes: 11247.7" "Cell type enhanced" "Detected in single" "choroid plexus epithelial cell: 1.2" "Cancer enriched" "Detected in many" 5 "Liver Hepatocellular Carcinoma (TCGA): 1092.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "colorectal cancer: 95.2;Gastric cancer: 40.0;liver cancer: 30.8" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA038713, HPA052451" Supported "Secreted to digestive system" "No annotated function" NA NA 61000000 "Cluster 77: Intestine - Digestion" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 1: Enterocytes - Absorption and Digestion" 7 "HPA038713: , HPA052451: " "unprognostic (2.48e-1)" "unprognostic (1.26e-2)" "unprognostic (1.55e-1)" "unprognostic (4.33e-3)" "unprognostic (2.51e-1)" "unprognostic (2.46e-2)" "unprognostic (4.53e-2)" "unprognostic (7.77e-3)" "unprognostic (1.06e-1)" "unprognostic (5.62e-2)" "unprognostic (1.19e-1)" "unprognostic (2.40e-3)" "unprognostic (6.97e-2)" "unprognostic (3.17e-1)" "unprognostic (1.74e-1)" "unprognostic (7.53e-2)" "unprognostic (1.38e-2)" "unprognostic (2.69e-1)" "unprognostic (1.61e-1)" "unprognostic (5.40e-2)" "unprognostic (2.03e-1)" "unprognostic (1.36e-1)" "unprognostic (8.11e-3)" PRB1 "PM, PMF, PMS, PRB1L, PRB1M" ENSG00000251655 "Proline rich protein BstNI subfamily 1" 12 11351823-11355591 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 1011 "salivary gland: 5973.3" "Group enriched" "Detected in some" 12 "Salivary acinar cells: 1821.1;Salivary myoepithelial cells: 574.0" "Cell type enhanced" "Detected in many" "medium spiny neuron: 20.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to digestive system" NA NA "Cluster 82: Salivary gland - Secretion" "Cluster 66: Non-specific - Mitochondria" "Cluster 38: Secretory epithelial cells - Exocrine secretion" PRB2 "cP7, PRPPRB1, Ps" ENSG00000121335 "Proline rich protein BstNI subfamily 2" P02812 12 11391540-11501041 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 3933 "salivary gland: 11382.0" "Cell type enriched" "Detected in many" 4 "Salivary acinar cells: 1687.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Secreted to digestive system" "No annotated function" NA NA "Cluster 82: Salivary gland - Secretion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 38: Secretory epithelial cells - Exocrine secretion" "unprognostic (4.01e-1)" "unprognostic (1.73e-2)" "unprognostic (1.50e-2)" "unprognostic (4.72e-1)" PRB3 PRG ENSG00000197870 "Proline rich protein BstNI subfamily 3" Q04118 12 11265914-11269707 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 1931 "salivary gland: 13016.8" "Group enriched" "Detected in some" 14 "Salivary acinar cells: 13838.1;Salivary myoepithelial cells: 4669.6" "Cell type enhanced" "Detected in single" "leukocyte: 1.0" "Group enriched" "Detected in some" 7 "Head and Neck Squamous Cell Carcinoma (TCGA): 2.8;Lung Adenocarcinoma (TCGA): 1.6;Lung Squamous Cell Carcinoma (TCGA): 2.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Secreted to digestive system" "No annotated function" NA NA 21000000 "Cluster 82: Salivary gland - Secretion" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 5 "unprognostic (1.75e-1)" "unprognostic (5.39e-2)" "unprognostic (1.40e-1)" "unprognostic (1.47e-1)" "unprognostic (7.34e-2)" PRB4 ENSG00000230657 "Proline rich protein BstNI subfamily 4" 12 11307077-11310436 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 211 "salivary gland: 3431.2" "Group enriched" "Detected in some" 11 "Salivary acinar cells: 4714.0;Salivary myoepithelial cells: 2482.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Lung Squamous Cell Carcinoma (TCGA): 2.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Secreted to digestive system" NA NA "Cluster 82: Salivary gland - Secretion" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 38: Secretory epithelial cells - Exocrine secretion" "unprognostic (4.25e-1)" PRC1 ASE1 ENSG00000198901 "Protein regulator of cytokinesis 1" O43663 15 90966040-90995629 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division" Oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 84.5;testis: 50.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 25.7;Differentiating spermatogonia: 57.5;Early primary spermatocytes: 72.6;Early spermatids: 27.3;Enteric transient amplifying cells: 40.9;Erythrocyte progenitors: 80.7;Extravillous trophoblasts: 37.2;Gastric progenitor cells: 32.0;Late primary spermatocytes: 55.7;Megakaryocyte progenitors: 48.4;Migrating cytotrophoblasts: 30.4;Monocyte progenitors: 55.3;Oocytes: 55.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 34.4" "Lineage enriched" "Detected in many" 4 "granulocytes: 34.4" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA034521, HPA048816" Enhanced Supported "Nucleoplasm,Plasma membrane,Microtubules,Cytokinetic bridge,Midbody" Yes Yes "Cluster 42: Non-specific - Vesicular transport" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 2: Neurons - Nucleosome" "Cluster 58: Non-specific - Nuclear processes" "Cluster 27: Non-specific - Cell proliferation" 35 "Microtubules, Cytokinetic bridge, Midbody" "Nucleoplasm, Plasma membrane" "HPA034521: , HPA048816: " "unprognostic (1.90e-1)" "unprognostic (7.46e-2)" "unprognostic (1.11e-1)" "unprognostic (1.36e-2)" "unprognostic (2.41e-1)" "unprognostic (4.15e-2)" "unprognostic (3.77e-1)" "potential prognostic favorable (5.62e-4)" "unprognostic (1.04e-1)" "unprognostic (2.40e-3)" "potential prognostic unfavorable (4.71e-9)" "unprognostic (1.47e-3)" "potential prognostic unfavorable (7.60e-9)" "validated prognostic unfavorable (7.19e-5)" "validated prognostic unfavorable (1.27e-7)" "validated prognostic unfavorable (3.40e-6)" "validated prognostic unfavorable (1.32e-4)" "unprognostic (2.24e-2)" "unprognostic (7.46e-2)" "unprognostic (2.82e-2)" "unprognostic (1.51e-2)" "potential prognostic unfavorable (5.00e-5)" "unprognostic (3.85e-3)" "unprognostic (1.61e-2)" "unprognostic (2.19e-1)" "unprognostic (6.62e-2)" "unprognostic (2.75e-2)" "unprognostic (1.34e-1)" "unprognostic (3.21e-1)" "unprognostic (8.26e-2)" "unprognostic (3.25e-1)" PRCC RCCP1 ENSG00000143294 "Proline rich mitotic checkpoint control factor" Q92733 1 156750610-156800815 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017151, HPA019463, HPA019481" Supported Enhanced "Nuclear speckles" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 7 "Nuclear speckles" "CAB017151: , HPA019463: , HPA019481: " "unprognostic (2.46e-1)" "unprognostic (5.73e-2)" "unprognostic (1.78e-1)" "unprognostic (6.50e-2)" "unprognostic (1.80e-2)" "unprognostic (1.36e-1)" "unprognostic (2.45e-1)" "unprognostic (1.81e-1)" "unprognostic (3.17e-1)" "unprognostic (7.67e-2)" "unprognostic (8.02e-3)" "unprognostic (2.56e-2)" "potential prognostic unfavorable (1.17e-4)" "potential prognostic unfavorable (7.90e-5)" "unprognostic (2.62e-2)" "unprognostic (2.61e-2)" "unprognostic (2.22e-3)" "unprognostic (5.00e-2)" "unprognostic (2.46e-2)" "unprognostic (3.17e-2)" "unprognostic (3.16e-1)" "unprognostic (9.15e-2)" "unprognostic (3.76e-2)" "unprognostic (2.01e-2)" "unprognostic (5.19e-2)" "unprognostic (2.06e-1)" "unprognostic (5.58e-2)" "unprognostic (1.64e-1)" "unprognostic (3.84e-2)" "unprognostic (1.54e-3)" "unprognostic (1.42e-1)" PRCD RP36 ENSG00000214140 "Photoreceptor disc component" Q00LT1 17 76527586-76553578 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "retina: 44.6" "Cell type enhanced" "Detected in many" "B-cells: 27.1;Cone photoreceptor cells: 95.2;Pericytes: 31.8;Retinal bipolar cells: 59.9;Retinal pigment epithelial cells: 42.6;Rod photoreceptor cells: 330.5;Thymocytes: 26.3" "Cell type enhanced" "Detected in many" "oligodendrocyte: 31.7" "Cancer enriched" "Detected in single" 9 "Uterine Corpus Endometrial Carcinoma (TCGA): 3.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Neuroblastoma: 3.3" "Pituitary gland - Fibroblasts, Prostate - Fibroblasts, Skin - Endothelial cells" "Low region specificity" "Detected in many" "Intracellular and membrane" Other NA NA "Cluster 42: Retina - Visual perception" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 79: Photoreceptor cells - Phototransduction" "unprognostic (9.48e-3)" "unprognostic (1.87e-1)" "unprognostic (2.03e-1)" "unprognostic (5.17e-2)" "unprognostic (2.31e-1)" PRCP "HUMPCP, PCP" ENSG00000137509 Prolylcarboxypeptidase P42785 11 82822936-82970584 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bergmann glia: 243.7;cDC: 210.4;Kupffer cells: 375.1;Neutrophils: 328.4;Vascular endothelial cells: 213.7" "Cell type enhanced" "Detected in all" "Bergmann glia: 269.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Macrophages, Spleen - Macrophages, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017065, HPA071115" Approved Supported Vesicles "Intracellular and membrane" Enzyme NA NA 17000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 28: Liver & Adrenal gland - Secretion" "Cluster 44: Non-specific - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 7 Vesicles "HPA017065: , HPA071115: " "unprognostic (2.21e-2)" "unprognostic (3.20e-1)" "unprognostic (1.39e-1)" "unprognostic (9.86e-2)" "unprognostic (1.70e-1)" "unprognostic (1.24e-2)" "unprognostic (3.71e-1)" "unprognostic (3.27e-1)" "unprognostic (2.56e-1)" "unprognostic (6.87e-3)" "potential prognostic favorable (2.28e-5)" "unprognostic (1.36e-1)" "unprognostic (4.33e-2)" "unprognostic (3.33e-2)" "unprognostic (6.57e-2)" "unprognostic (2.59e-1)" "unprognostic (5.72e-3)" "unprognostic (3.11e-3)" "unprognostic (2.45e-1)" "unprognostic (5.96e-2)" "unprognostic (5.51e-2)" "unprognostic (2.62e-1)" "unprognostic (3.73e-2)" "unprognostic (1.76e-1)" "unprognostic (4.36e-1)" "unprognostic (6.47e-2)" "unprognostic (2.49e-2)" "unprognostic (3.50e-3)" "unprognostic (6.94e-2)" "unprognostic (4.33e-1)" "unprognostic (2.42e-1)" PRDM1 "BLIMP1, PRDI-BF1" ENSG00000057657 "PR/SET domain 1" O75626 6 105993463-106109939 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Adaptive immunity, Immunity, Innate immunity, Transcription, Transcription regulation" "DNA-binding, Methyltransferase, Repressor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 51.9" "Group enriched" "Detected in many" 4 "Esophageal apical cells: 1165.4;Plasma cells: 814.6" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 80.2;leukocyte: 94.9;MGE interneuron: 61.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "eosinophil: 11.0;gdT-cell: 22.0;MAIT T-cell: 33.7;memory CD4 T-cell: 20.3;memory CD8 T-cell: 20.0;naive CD8 T-cell: 11.2;neutrophil: 12.5;T-reg: 29.2" "Group enriched" "Detected in many" 5 "granulocytes: 12.5;T-cells: 33.7" "Cancer enriched" "Detected in many" 4 "Myeloma: 91.1" "Colon - T-cells, Prostate - T-cells" "Region enriched" "Detected in single" 6 "olfactory bulb: 3.6" "Low region specificity" "Detected in many" "HPA030033, HPA075427" Approved Supported Nucleoplasm,Nucleoli NA NA "Cluster 1: T-cells - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 67: Plasma cells - Plasma cell differentiation" 15 Nucleoli Nucleoplasm "HPA030033: , HPA075427: " "unprognostic (6.29e-2)" "unprognostic (1.29e-1)" "unprognostic (3.34e-2)" "unprognostic (2.23e-2)" "unprognostic (3.73e-2)" "unprognostic (2.03e-1)" "unprognostic (4.76e-2)" "unprognostic (2.29e-2)" "unprognostic (8.13e-2)" "unprognostic (6.20e-2)" "unprognostic (5.39e-3)" "potential prognostic favorable (6.30e-5)" "unprognostic (1.68e-2)" "unprognostic (2.13e-1)" "unprognostic (3.01e-1)" "unprognostic (6.38e-2)" "unprognostic (2.83e-1)" "unprognostic (1.27e-1)" "unprognostic (4.00e-1)" "unprognostic (1.08e-1)" "unprognostic (3.36e-2)" "unprognostic (6.17e-3)" "unprognostic (2.39e-3)" "unprognostic (9.24e-2)" "unprognostic (2.98e-1)" "unprognostic (6.64e-3)" "unprognostic (1.39e-1)" "unprognostic (4.49e-2)" "unprognostic (1.41e-1)" "unprognostic (2.47e-3)" "unprognostic (1.53e-2)" PRDM10 "KIAA1231, MGC131802, PFM7" ENSG00000170325 "PR/SET domain 10" Q9NQV6 11 129899706-130002835 "Essential proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Neutrophils: 105.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026997, HPA061749" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 2 Nucleoplasm "Nucleoli fibrillar center, Vesicles" "HPA026997: , HPA061749: " "unprognostic (2.55e-1)" "unprognostic (3.18e-2)" "unprognostic (5.08e-1)" "unprognostic (9.78e-3)" "unprognostic (2.94e-1)" "unprognostic (1.10e-1)" "unprognostic (6.94e-2)" "unprognostic (5.06e-3)" "unprognostic (1.02e-2)" "unprognostic (9.83e-2)" "validated prognostic favorable (7.99e-4)" "validated prognostic favorable (1.69e-4)" "unprognostic (1.47e-1)" "unprognostic (1.82e-2)" "unprognostic (2.23e-1)" "unprognostic (5.06e-2)" "unprognostic (7.96e-2)" "unprognostic (3.41e-1)" "unprognostic (3.58e-2)" "unprognostic (3.31e-2)" "unprognostic (5.97e-3)" "unprognostic (1.90e-2)" "unprognostic (6.68e-2)" "unprognostic (6.25e-2)" "unprognostic (5.14e-3)" "unprognostic (6.17e-3)" "unprognostic (2.69e-3)" "unprognostic (1.06e-1)" "unprognostic (2.75e-1)" "unprognostic (3.95e-2)" "unprognostic (1.46e-1)" PRDM11 PFM8 ENSG00000019485 "PR/SET domain 11" Q9NQV5 11 45095806-45235110 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 85.2;Microglia: 293.8" "Cell type enriched" "Detected in all" 9 "central nervous system macrophage: 349.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057072 Approved NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 1 "HPA057072: " "unprognostic (2.11e-1)" "unprognostic (2.91e-2)" "unprognostic (2.07e-1)" "unprognostic (1.41e-2)" "unprognostic (2.44e-1)" "unprognostic (1.53e-2)" "unprognostic (2.34e-1)" "potential prognostic favorable (1.78e-4)" "unprognostic (2.24e-2)" "unprognostic (1.68e-1)" "unprognostic (2.86e-3)" "unprognostic (1.66e-3)" "potential prognostic favorable (8.36e-4)" "unprognostic (1.00e-3)" "unprognostic (1.52e-2)" "unprognostic (2.65e-2)" "unprognostic (2.34e-1)" "unprognostic (4.09e-3)" "unprognostic (2.76e-1)" "unprognostic (1.57e-1)" "unprognostic (9.94e-3)" "unprognostic (2.68e-2)" "unprognostic (3.82e-1)" "unprognostic (2.88e-3)" "unprognostic (4.32e-2)" "unprognostic (7.52e-2)" "unprognostic (5.54e-2)" "unprognostic (9.92e-2)" "unprognostic (1.64e-3)" "unprognostic (3.76e-1)" PRDM12 PFM9 ENSG00000130711 "PR/SET domain 12" Q9H4Q4 9 130664594-130682986 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 5 "brain: 1.0" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 1.4;Brain inhibitory neurons: 1.8;Kupffer cells: 1.0;Other brain neurons: 3.7" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "basal ganglia: 5.5;hypothalamus: 4.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 16 "Sarcoma: 10.8" "Region enriched" "Detected in some" 7 "basal ganglia: 10.9" "Group enriched" "Detected in some" 24 "basal ganglia: 4.7;hypothalamus: 1.6" HPA043143 Uncertain Approved Nucleoplasm NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 98: Neurons - Neurotransmission & signaling" Nucleoplasm "HPA043143: " PRDM13 PFM10 ENSG00000112238 "PR/SET domain 13" Q9H4Q3 6 99606774-99615578 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Hypogonadotropic hypogonadism, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 1.2;Oocytes: 9.2;Retinal amacrine cells: 2.8;Undifferentiated spermatogonia: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 16 "hypothalamus: 1.2;medulla oblongata: 2.1;spinal cord: 1.4;white matter: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046046, HPA062648, HPA069705, HPA070592" Uncertain Approved "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 22: Non-specific - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 41: Oocytes - Oogenesis" "Nucleoplasm, Nuclear speckles" Cytosol "HPA046046: , HPA062648: , HPA069705: , HPA070592: " "unprognostic (1.53e-1)" PRDM14 ENSG00000147596 "PR/SET domain 14" Q9GZV8 8 70051651-70071693 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Cone photoreceptor cells: 2.1;Hepatic stellate cells: 6.5;Thymocytes: 3.4;Undifferentiated spermatogonia: 2.6" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 106 "Testicular Germ Cell Tumor (TCGA): 48.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 9 "testis cancer: 12.1" "Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" HPA019094 Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 6: Non-specific - Immune response" "Cluster 34: Testis cancer - Unknown function" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 54 Nucleoplasm Vesicles "HPA019094: " "unprognostic (7.79e-2)" PRDM15 "C21orf83, ZNF298" ENSG00000141956 "PR/SET domain 15" P57071 21 41798225-41879482 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Methyltransferase, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 33.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "lymphoma: 21.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024268, HPA029255, HPA029256" Uncertain Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 51: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 44: Plasma cells - Antibody production & secretion" 7 "Nuclear bodies" Nucleoplasm "HPA024268: , HPA029255: , HPA029256: " "unprognostic (3.65e-2)" "unprognostic (1.59e-2)" "unprognostic (1.95e-2)" "unprognostic (2.28e-1)" "unprognostic (3.02e-2)" "unprognostic (4.39e-1)" "unprognostic (3.75e-1)" "potential prognostic favorable (3.74e-4)" "potential prognostic favorable (1.00e-4)" "unprognostic (1.95e-1)" "unprognostic (3.17e-1)" "unprognostic (1.02e-1)" "unprognostic (1.02e-2)" "potential prognostic unfavorable (9.35e-5)" "unprognostic (1.92e-1)" "unprognostic (3.72e-1)" "unprognostic (7.30e-2)" "unprognostic (1.29e-1)" "unprognostic (1.04e-2)" "unprognostic (8.05e-2)" "unprognostic (1.58e-1)" "unprognostic (1.42e-1)" "unprognostic (3.43e-3)" "unprognostic (7.31e-2)" "unprognostic (4.18e-2)" "potential prognostic favorable (8.44e-4)" "unprognostic (2.29e-1)" "unprognostic (7.75e-2)" "unprognostic (4.31e-2)" "unprognostic (4.10e-2)" "unprognostic (1.98e-1)" PRDM16 "KIAA1675, KMT8F, MEL1, MGC166915, PFM13" ENSG00000142611 "PR/SET domain 16" Q9HAZ2 1 3069168-3438621 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding, Methyltransferase, Repressor, Transferase" "Cancer-related genes, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 18.0" "Cell type enhanced" "Detected in many" "Astrocytes: 222.4;Cardiomyocytes: 202.9;Choroid plexus epithelial cells: 859.4;Distal convoluted tubule cells: 277.9;Loop of henle epithelial cells: 247.3;Renal collecting duct intercalated cells: 308.4;Renal collecting duct principal cells: 315.5;Renal connecting tubule cells: 382.9;Retinal pigment epithelial cells: 319.7;Vascular smooth muscle cells: 152.6" "Cell type enhanced" "Detected in many" "astrocyte: 195.6;choroid plexus epithelial cell: 612.6" "Cancer enhanced" "Detected in some" "Kidney Chromophobe (TCGA): 6.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 16 "NK-cell: 2.4" "Lineage enriched" "Detected in single" 16 "NK-cells: 2.4" "Cancer enhanced" "Detected in many" "Bile duct cancer: 4.6" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Adrenal gland - Smooth muscle cells, Breast - Endothelial cells, Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Kidney - Ascending Loop of Henle cells, Minor Salivary Gland - Endothelial cells, Skeletal muscle - Smooth muscle cells, Stomach - Gastric mucous cells" "Region enriched" "Detected in many" 5 "basal ganglia: 15.7" "Low region specificity" "Detected in many" "HPA050343, HPA051662" Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 23: Choroid plexus - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 8 Nucleoplasm "Nuclear bodies, Cytosol" "HPA050343: , HPA051662: " "unprognostic (2.18e-1)" "unprognostic (3.26e-2)" "unprognostic (3.38e-1)" "unprognostic (2.18e-1)" "unprognostic (3.33e-2)" "unprognostic (1.70e-3)" "unprognostic (6.41e-2)" "unprognostic (8.60e-2)" "unprognostic (6.37e-2)" "unprognostic (1.24e-1)" "unprognostic (2.59e-1)" "potential prognostic unfavorable (3.57e-4)" PRDM2 "HUMHOXY1, KMT8, KMT8A, MTB-ZF, RIZ, RIZ1, RIZ2" ENSG00000116731 "PR/SET domain 2" Q13029 1 13700188-13825079 "Enzymes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "B-cells: 675.9;Neutrophil progenitors: 516.4;Neutrophils: 521.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005809 Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 53: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 7 "Nucleoplasm, Golgi apparatus" "HPA005809: " "unprognostic (1.85e-2)" "unprognostic (1.17e-1)" "unprognostic (2.50e-1)" "unprognostic (5.50e-2)" "unprognostic (2.52e-1)" "unprognostic (8.75e-2)" "unprognostic (1.31e-1)" "unprognostic (1.64e-1)" "unprognostic (1.21e-3)" "unprognostic (1.53e-2)" "unprognostic (6.45e-3)" "unprognostic (3.50e-2)" "unprognostic (5.73e-2)" "unprognostic (4.29e-2)" "unprognostic (2.14e-1)" "unprognostic (3.74e-3)" "unprognostic (1.33e-1)" "unprognostic (1.45e-1)" "unprognostic (3.28e-1)" "unprognostic (8.61e-3)" "unprognostic (9.15e-2)" "unprognostic (4.25e-1)" "unprognostic (3.82e-2)" "unprognostic (2.24e-1)" "unprognostic (8.12e-2)" "potential prognostic favorable (6.62e-6)" "unprognostic (1.40e-1)" "unprognostic (2.93e-1)" "unprognostic (2.89e-1)" "unprognostic (8.37e-2)" "unprognostic (9.71e-2)" PRDM4 PFM1 ENSG00000110851 "PR/SET domain 4" Q9UKN5 12 107732871-107761272 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 126.1;Renal collecting duct intercalated cells: 96.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024322, HPA067437" Approved Supported Nucleoplasm NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 38: Non-specific - Transcription" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 3 Nucleoplasm "HPA024322: , HPA067437: " "unprognostic (5.63e-3)" "unprognostic (2.03e-2)" "unprognostic (8.30e-2)" "potential prognostic unfavorable (2.10e-5)" "unprognostic (1.02e-2)" "unprognostic (3.73e-2)" "unprognostic (3.62e-1)" "unprognostic (1.71e-2)" "unprognostic (2.02e-1)" "unprognostic (3.09e-1)" "potential prognostic favorable (3.50e-5)" "unprognostic (2.51e-2)" "unprognostic (3.37e-2)" "potential prognostic unfavorable (4.99e-4)" "unprognostic (1.52e-1)" "unprognostic (7.75e-3)" "unprognostic (3.95e-3)" "unprognostic (7.97e-2)" "unprognostic (3.63e-2)" "unprognostic (1.02e-2)" "unprognostic (3.60e-2)" "unprognostic (5.25e-2)" "unprognostic (3.77e-2)" "unprognostic (9.83e-2)" "unprognostic (2.64e-2)" "unprognostic (8.72e-3)" "unprognostic (3.45e-2)" "unprognostic (1.37e-1)" "unprognostic (3.70e-1)" "unprognostic (8.52e-2)" "unprognostic (1.09e-2)" PRDM5 PFM2 ENSG00000138738 "PR/SET domain 5" Q9NQX1 4 120684919-120922870 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Chromatin regulator, DNA-binding, Methyltransferase, Repressor, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 316.2;Corticotrophs: 149.0;Ependymal cells: 177.9;Gonadotrophs: 185.2;Lactotrophs: 167.1;Neutrophil progenitors: 163.6;Neutrophils: 182.0;Pituicytes/FSCs: 229.8;Podocytes: 318.8" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 247.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 27 "eosinophil: 7.5;neutrophil: 5.4" "Lineage enriched" "Detected in single" 31 "granulocytes: 7.5" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051406 Enhanced Supported "Nucleoplasm,Nucleoli,Nuclear bodies" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 44: Non-specific - Mixed function" "Cluster 20: Myeloma - Immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 3 "Nucleoli, Nuclear bodies" Nucleoplasm "HPA051406: " "unprognostic (1.48e-1)" "unprognostic (9.62e-2)" "unprognostic (1.32e-2)" "unprognostic (8.41e-2)" "unprognostic (1.28e-2)" "unprognostic (3.90e-2)" "unprognostic (2.16e-2)" "unprognostic (2.01e-2)" "unprognostic (2.28e-2)" "unprognostic (5.25e-2)" "unprognostic (7.62e-2)" "unprognostic (1.46e-1)" "unprognostic (1.55e-1)" "unprognostic (9.50e-2)" "unprognostic (1.87e-2)" "unprognostic (1.65e-1)" "unprognostic (8.32e-2)" "unprognostic (4.90e-2)" "unprognostic (1.29e-1)" "unprognostic (3.17e-1)" "unprognostic (2.31e-2)" "unprognostic (8.05e-2)" "unprognostic (7.34e-2)" "potential prognostic unfavorable (4.26e-4)" "unprognostic (9.46e-2)" PRDM6 "KMT8C, PRISM" ENSG00000061455 "PR/SET domain 6" Q9NQX0 5 123089241-123194266 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "blood vessel: 14.8;urinary bladder: 8.8" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 19.9;Cone photoreceptor cells: 24.8;Endometrial stromal cells: 39.1;Ependymal cells: 31.1;Fibro-adipogenic progenitors: 50.2;Fibroblasts: 44.6;Mesothelial cells: 42.5;Ovarian stromal cells: 32.7;Smooth muscle cells: 78.6;Undifferentiated spermatogonia: 39.3;Vascular smooth muscle cells: 28.3" "Cell type enhanced" "Detected in many" "fibroblast: 85.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Fibroblasts, Prostate - Smooth muscle cells, Stomach - Fibroblasts, Testis - Spermatogonia" "Not detected" "Not detected" "Region enhanced" "Detected in some" "spinal cord: 3.1" HPA030324 Uncertain Approved Nucleoplasm NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 45: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 108: Fibroblasts - ECM organization" 49 Nucleoplasm "HPA030324: " "unprognostic (8.25e-2)" "unprognostic (3.79e-1)" "unprognostic (5.88e-2)" "unprognostic (1.03e-1)" "unprognostic (2.95e-2)" PRDM7 ZNF910 ENSG00000126856 "PR/SET domain 7" Q9NQW5 16 90056566-90092072 "Predicted intracellular proteins" "Chromatin regulator, Methyltransferase, Transferase" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 35 "Early primary spermatocytes: 63.6" "Cell type enhanced" "Detected in some" "midbrain-derived inhibitory: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 25 "skin cancer: 2.4" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA059944 Approved Uncertain "Nuclear speckles" NA NA "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 3: Early primary spermatocytes - Early meiosis" 1 "Nuclear speckles" "HPA059944: " PRDM8 KMT8D ENSG00000152784 "PR/SET domain 8" Q9NQV8 4 80183879-80204329 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Neurogenesis, Transcription, Transcription regulation" "DNA-binding, Methyltransferase, Transferase" "Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 25.1;seminal vesicle: 25.6" "Cell type enriched" "Detected in many" 5 "Retinal bipolar cells: 285.4" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 89.0;hippocampal CA4: 174.0" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 9.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal medulla cells, Breast - Fibroblasts, Pituitary gland - Somatotropes, Stomach - Fibroblasts" "Region enhanced" "Detected in many" "hippocampal formation: 28.7" "Low region specificity" "Detected in all" HPA057253 Supported "Nucleoplasm,Nuclear bodies" No NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "Nuclear bodies" Nucleoplasm "HPA057253: " "unprognostic (1.28e-2)" "unprognostic (2.63e-3)" "unprognostic (3.06e-2)" "unprognostic (1.20e-1)" "unprognostic (6.53e-2)" "unprognostic (1.85e-1)" "unprognostic (1.06e-2)" "potential prognostic unfavorable (4.45e-4)" "unprognostic (1.44e-1)" "unprognostic (4.15e-2)" "unprognostic (5.75e-3)" "unprognostic (2.42e-1)" "unprognostic (7.25e-2)" "unprognostic (1.94e-1)" "unprognostic (2.34e-3)" "unprognostic (2.53e-2)" "unprognostic (1.74e-2)" "unprognostic (2.78e-2)" "unprognostic (1.74e-1)" PRDM9 "KMT8B, Meisetz, MSBP3, PFM6, ZNF899" ENSG00000164256 "PR/SET domain 9" Q9NQV7 5 23443586-23528093 "Enzymes, Predicted intracellular proteins, Transcription factors" "Meiosis, Transcription, Transcription regulation" "Activator, Chromatin regulator, DNA-binding, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "epididymis: 1.5;testis: 4.1" "Cell type enriched" "Detected in some" 5 "Early primary spermatocytes: 72.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.1" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in some" "Myeloma: 2.2;thyroid cancer: 3.7" "Testis - Spermatocytes" HPA059555 Uncertain NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 3: Early primary spermatocytes - Early meiosis" "HPA059555: " "unprognostic (1.64e-1)" "unprognostic (3.81e-1)" PRDX1 "NKEFA, PAGA" ENSG00000117450 "Peroxiredoxin 1" Q06830 1 45510914-45542732 "Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Antioxidant, Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 3623.3;Esophageal basal cells: 2324.3;Esophageal suprabasal cells: 3653.4;Extravillous trophoblasts: 2279.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004682, HPA007730" Approved Approved Mitochondria NA NA 75000000 "Cluster 33: Non-specific - ATP binding" "Cluster 76: Non-specific - Metabolism" "Cluster 27: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 85: Squamous epithelial cells - Keratinization" 59 Mitochondria "CAB004682: , HPA007730: " "potential prognostic unfavorable (1.02e-4)" "potential prognostic unfavorable (1.03e-4)" "unprognostic (6.45e-2)" "unprognostic (2.39e-2)" "unprognostic (9.12e-2)" "unprognostic (1.33e-1)" "unprognostic (4.79e-2)" "unprognostic (2.61e-1)" "unprognostic (2.81e-2)" "unprognostic (3.93e-2)" "unprognostic (2.23e-2)" "unprognostic (1.70e-1)" "unprognostic (2.93e-2)" "potential prognostic unfavorable (3.64e-7)" "unprognostic (4.82e-3)" "unprognostic (8.68e-3)" "unprognostic (3.92e-2)" "unprognostic (1.52e-1)" "unprognostic (3.61e-1)" "unprognostic (1.00e-1)" "unprognostic (2.43e-2)" "unprognostic (3.71e-2)" "unprognostic (1.19e-1)" "unprognostic (1.65e-1)" "unprognostic (3.90e-2)" "unprognostic (3.98e-2)" "unprognostic (1.82e-1)" "unprognostic (6.96e-2)" "unprognostic (2.34e-1)" "unprognostic (3.26e-1)" "unprognostic (3.10e-1)" PRDX2 "MGC4104, NKEFB, PRP, PRX2, PRXII, TDPX1, TSA" ENSG00000167815 "Peroxiredoxin 2" P32119 19 12796820-12801800 "Cancer-related genes, Enzymes, Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Antioxidant, Oxidoreductase, Peroxidase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 1334.5;Erythrocytes: 361.3;Parietal cells: 624.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008713, CAB080246" Supported Supported Cytosol NA NA 580000000 "Cluster 6: T-cells - T-cell receptor" "Cluster 52: Non-specific - Cellular respiration" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 23: Non-specific - Transcription" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 50 Cytosol "CAB008713: , CAB080246: " "unprognostic (2.37e-1)" "unprognostic (5.69e-2)" "unprognostic (3.54e-1)" "potential prognostic favorable (4.23e-4)" "unprognostic (2.92e-2)" "unprognostic (1.87e-1)" "unprognostic (7.28e-2)" "unprognostic (1.76e-1)" "unprognostic (6.82e-2)" "unprognostic (3.52e-3)" "validated prognostic favorable (7.87e-7)" "validated prognostic favorable (6.45e-4)" "potential prognostic favorable (1.13e-6)" "unprognostic (8.18e-2)" "unprognostic (3.62e-3)" "unprognostic (2.57e-2)" "unprognostic (1.06e-2)" "potential prognostic favorable (6.05e-4)" "unprognostic (1.08e-1)" "unprognostic (2.65e-2)" "unprognostic (3.81e-1)" "unprognostic (5.69e-2)" "unprognostic (1.11e-1)" "unprognostic (6.55e-3)" "unprognostic (5.02e-2)" "unprognostic (1.93e-2)" "unprognostic (1.91e-1)" "unprognostic (9.79e-2)" "unprognostic (2.06e-1)" "unprognostic (1.50e-1)" "unprognostic (2.21e-1)" PRDX3 "AOP-1, AOP1, MER5, SP-22" ENSG00000165672 "Peroxiredoxin 3" P30048 10 119167720-119178812 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Antioxidant, Oxidoreductase, Peroxidase" "Corneal dystrophy, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 371.8;Gastric progenitor cells: 352.5;Hepatocytes: 435.8;Migrating cytotrophoblasts: 346.7;Parietal cells: 611.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008656, HPA041488, HPA063551, CAB079909" Enhanced Supported Vesicles,Mitochondria NA NA 2300000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 52: Non-specific - Mitochondria" "Cluster 97: Non-specific - Cellular respiration" 26 "Vesicles, Mitochondria" "CAB008656: , CAB079909: , HPA041488: , HPA063551: " "unprognostic (1.86e-1)" "unprognostic (1.40e-2)" "unprognostic (2.03e-1)" "unprognostic (1.61e-1)" "unprognostic (1.75e-2)" "unprognostic (2.43e-2)" "unprognostic (1.29e-1)" "unprognostic (8.11e-2)" "unprognostic (2.68e-3)" "unprognostic (1.11e-1)" "potential prognostic favorable (2.12e-8)" "unprognostic (1.51e-1)" "unprognostic (2.94e-1)" "potential prognostic favorable (8.70e-4)" "unprognostic (6.69e-2)" "unprognostic (2.51e-2)" "unprognostic (9.77e-2)" "unprognostic (1.99e-1)" "unprognostic (1.83e-1)" "unprognostic (2.96e-1)" "unprognostic (1.46e-2)" "potential prognostic unfavorable (9.89e-4)" "unprognostic (2.47e-1)" "unprognostic (9.94e-2)" "unprognostic (3.04e-2)" "unprognostic (1.63e-1)" "unprognostic (6.64e-2)" "unprognostic (1.98e-1)" "unprognostic (1.44e-1)" "unprognostic (4.92e-1)" "unprognostic (2.14e-1)" PRDX4 AOE37-2 ENSG00000123131 "Peroxiredoxin 4" Q13162 X 23664262-23686397 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Antioxidant, Oxidoreductase, Peroxidase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "pancreas: 1142.7" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 557.5;Extravillous trophoblasts: 707.8;Hepatocytes: 575.5;Late spermatids: 1561.4;Pancreatic acinar cells: 899.3;Plasma cells: 956.0" "Cell type enhanced" "Detected in all" "pericyte: 43.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Spleen - Plasma cells, Stomach - Chief cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008659, CAB027389, CAB047362, HPA067039, CAB080373, CAB080374" Enhanced Supported "Endoplasmic reticulum,Cytosol" "Intracellular and membrane" Enzyme NA NA 2300000 "Cluster 14: Non-specific - Unknown function" "Cluster 8: Pancreas - Proteolysis" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 44: Plasma cells - Antibody production & secretion" 31 "Endoplasmic reticulum" Cytosol "CAB008659: , CAB027389: , CAB047362: , CAB080373: , CAB080374: , HPA067039: " "potential prognostic unfavorable (9.00e-5)" "potential prognostic unfavorable (8.09e-4)" "unprognostic (4.54e-2)" "unprognostic (1.23e-1)" "unprognostic (9.96e-3)" "unprognostic (1.82e-2)" "unprognostic (1.92e-1)" "unprognostic (3.45e-2)" "unprognostic (1.01e-2)" "potential prognostic unfavorable (2.91e-4)" "potential prognostic favorable (7.58e-6)" "unprognostic (2.61e-2)" "potential prognostic unfavorable (2.37e-7)" "potential prognostic unfavorable (5.53e-4)" "unprognostic (4.43e-3)" "unprognostic (7.77e-3)" "unprognostic (1.29e-2)" "unprognostic (4.26e-1)" "unprognostic (1.92e-1)" "unprognostic (6.03e-2)" "unprognostic (1.45e-1)" "unprognostic (1.37e-1)" "unprognostic (2.26e-1)" "unprognostic (3.35e-2)" "unprognostic (9.48e-2)" "unprognostic (1.34e-2)" "unprognostic (2.87e-1)" "unprognostic (1.74e-1)" "unprognostic (1.54e-1)" "unprognostic (2.92e-2)" "unprognostic (2.36e-1)" PRDX5 "ACR1, AOEB166, B166, MGC117264, MGC142283, MGC142285, PLP, PMP20, PRDX6, PRXV, SBBI10" ENSG00000126432 "Peroxiredoxin 5" P30044 11 64318121-64321811 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Antioxidant, Oxidoreductase, Peroxidase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 1322.0" "Cell type enhanced" "Detected in all" "Enteric stem cells: 1543.6;Epididymal efferent duct ciliated cells: 2461.6;Esophageal apical cells: 4100.4;Esophageal suprabasal cells: 1925.4;Fallopian tube ciliated cells: 2319.4;Parietal cells: 1886.3;Respiratory ciliated cells: 2506.5" "Cell type enhanced" "Detected in all" "ependymal cell: 214.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008661, HPA037915, HPA037916" Enhanced Supported Mitochondria NA NA 6200000 "Cluster 29: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 107: Ciliated cells - Cilia assembly & function" 17 Mitochondria "CAB008661: , HPA037915: , HPA037916: " "unprognostic (1.73e-2)" "unprognostic (7.47e-2)" "unprognostic (1.64e-1)" "unprognostic (1.23e-1)" "unprognostic (3.85e-1)" "unprognostic (1.25e-3)" "unprognostic (1.44e-1)" "unprognostic (2.42e-1)" "unprognostic (2.69e-2)" "unprognostic (2.84e-3)" "unprognostic (6.01e-2)" "unprognostic (1.61e-1)" "unprognostic (9.58e-3)" "validated prognostic unfavorable (9.83e-5)" "validated prognostic unfavorable (5.27e-5)" "unprognostic (1.26e-1)" "unprognostic (1.71e-1)" "unprognostic (2.97e-2)" "unprognostic (9.96e-2)" "potential prognostic favorable (1.75e-5)" "unprognostic (1.37e-1)" "unprognostic (2.08e-3)" "unprognostic (3.56e-1)" "unprognostic (5.12e-1)" "unprognostic (7.81e-2)" "unprognostic (1.12e-1)" "unprognostic (9.78e-2)" "unprognostic (1.94e-1)" "unprognostic (2.96e-1)" "unprognostic (4.83e-2)" "unprognostic (1.80e-1)" PRDX6 "1-Cys, aiPLA2, AOP2, KIAA0106, MGC46173, NSGPx, p29, PRX" ENSG00000117592 "Peroxiredoxin 6" P30041 1 173477330-173488815 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Antioxidant, Hydrolase, Multifunctional enzyme, Oxidoreductase, Peroxidase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 1455.3;Esophageal apical cells: 2464.3;Extravillous trophoblasts: 1283.7;Hepatocytes: 1373.6;Platelets: 1131.5;Syncytiotrophoblasts: 1280.1" "Cell type enhanced" "Detected in all" "astrocyte: 162.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006983, CAB008663" Supported Supported "Plasma membrane,Cytosol" NA NA 73000000 "Cluster 13: Non-specific - Mitochondria" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 39: Astrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 38 "Plasma membrane, Cytosol" "CAB008663: , HPA006983: " "unprognostic (2.02e-2)" "unprognostic (3.09e-3)" "unprognostic (3.39e-1)" "unprognostic (2.14e-1)" "unprognostic (2.37e-2)" "unprognostic (2.33e-1)" "unprognostic (1.53e-1)" "unprognostic (7.21e-3)" "potential prognostic unfavorable (1.91e-5)" "unprognostic (1.45e-3)" "unprognostic (4.04e-2)" "unprognostic (2.09e-3)" "unprognostic (3.00e-3)" "unprognostic (4.20e-3)" "unprognostic (2.50e-1)" "unprognostic (3.21e-3)" "unprognostic (2.16e-1)" "unprognostic (3.53e-2)" "unprognostic (2.64e-1)" "unprognostic (1.79e-1)" "unprognostic (7.67e-2)" "unprognostic (8.79e-3)" "unprognostic (1.84e-1)" "unprognostic (1.25e-1)" "unprognostic (3.68e-1)" "unprognostic (9.30e-2)" "unprognostic (7.62e-3)" "unprognostic (1.08e-1)" "unprognostic (2.26e-2)" "unprognostic (1.06e-1)" "unprognostic (1.76e-2)" PREB SEC12 ENSG00000138073 "Prolactin regulatory element binding" Q9HCU5 2 27130756-27134666 "Essential proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "ER-Golgi transport, Protein transport, Transcription, Transcription regulation, Transport" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 126.6;Extravillous trophoblasts: 72.5;Plasma cells: 75.9;Syncytiotrophoblasts: 94.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013582, HPA014133" Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 45: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 8: Non-specific - Secretory pathway" 30 "Endoplasmic reticulum" "HPA013582: , HPA014133: " "unprognostic (1.39e-1)" "unprognostic (3.85e-2)" "unprognostic (1.49e-1)" "unprognostic (8.45e-2)" "unprognostic (7.11e-2)" "unprognostic (1.98e-1)" "potential prognostic unfavorable (6.38e-8)" "unprognostic (2.73e-1)" "unprognostic (2.07e-2)" "unprognostic (3.53e-2)" "unprognostic (1.95e-1)" "unprognostic (5.86e-2)" "unprognostic (1.05e-1)" "unprognostic (1.67e-3)" "unprognostic (2.35e-1)" "unprognostic (4.63e-3)" "unprognostic (2.24e-2)" "unprognostic (6.25e-2)" "unprognostic (1.62e-1)" "unprognostic (1.92e-3)" "unprognostic (2.71e-1)" "unprognostic (1.76e-1)" "unprognostic (7.97e-2)" "unprognostic (3.43e-1)" "unprognostic (8.25e-2)" "unprognostic (1.52e-1)" "unprognostic (2.98e-1)" "unprognostic (1.53e-1)" "unprognostic (3.29e-1)" "unprognostic (1.20e-1)" "unprognostic (3.66e-1)" PRELID1 "CGI-106, PRELI, PX19" ENSG00000169230 "PRELI domain containing 1" Q9Y255 5 177303799-177306949 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 890.0;Enterocytes: 620.8;Esophageal apical cells: 1031.9;Esophageal basal cells: 589.0;Esophageal suprabasal cells: 730.5;Extravillous trophoblasts: 587.5;Migrating cytotrophoblasts: 705.6;Syncytiotrophoblasts: 1028.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005701 Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 45: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 12 Mitochondria Nucleoplasm "HPA005701: " "unprognostic (3.06e-3)" "unprognostic (1.48e-1)" "unprognostic (1.19e-2)" "unprognostic (5.01e-2)" "unprognostic (1.59e-2)" "unprognostic (1.77e-1)" "unprognostic (4.98e-2)" "unprognostic (1.93e-1)" "unprognostic (7.08e-2)" "potential prognostic unfavorable (7.85e-4)" "unprognostic (7.24e-2)" "unprognostic (3.09e-3)" "unprognostic (3.46e-2)" "validated prognostic unfavorable (2.05e-4)" "validated prognostic unfavorable (7.70e-6)" "potential prognostic unfavorable (2.02e-4)" "unprognostic (1.25e-3)" "unprognostic (1.07e-1)" "unprognostic (2.67e-2)" "unprognostic (8.99e-3)" "unprognostic (5.03e-2)" "unprognostic (3.36e-2)" "unprognostic (7.12e-2)" "unprognostic (1.60e-1)" "unprognostic (2.34e-1)" "unprognostic (1.71e-1)" "unprognostic (9.75e-2)" "unprognostic (6.55e-2)" "unprognostic (2.01e-1)" "unprognostic (2.12e-1)" "unprognostic (1.77e-2)" PRELID2 "FLJ38376, MGC21644" ENSG00000186314 "PRELI domain containing 2" Q8N945 5 145471799-145835369 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 20.7;retina: 14.6" "Cell type enriched" "Detected in many" 4 "Cone photoreceptor cells: 2117.7" "Cell type enhanced" "Detected in all" "CGE interneuron: 595.0;LAMP5-LHX6 and Chandelier: 533.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 24.4" "Lineage enriched" "Detected in all" 4 "granulocytes: 24.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA042486 Uncertain Approved Nucleoplasm NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 53: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 79: Photoreceptor cells - Phototransduction" Nucleoplasm "HPA042486: " "unprognostic (1.28e-1)" "unprognostic (2.91e-2)" "unprognostic (2.23e-1)" "unprognostic (6.53e-2)" "unprognostic (1.39e-1)" "unprognostic (2.37e-2)" "unprognostic (8.33e-3)" "unprognostic (1.71e-3)" "potential prognostic unfavorable (9.84e-4)" "potential prognostic unfavorable (1.25e-4)" "validated prognostic favorable (2.16e-7)" "validated prognostic favorable (2.82e-4)" "unprognostic (7.57e-2)" "potential prognostic unfavorable (4.76e-6)" "unprognostic (3.11e-3)" "unprognostic (1.49e-2)" "unprognostic (1.27e-3)" "unprognostic (9.42e-2)" "unprognostic (8.47e-2)" "unprognostic (1.66e-1)" "unprognostic (6.50e-3)" "potential prognostic unfavorable (8.63e-4)" "unprognostic (5.69e-2)" "unprognostic (3.39e-1)" "unprognostic (1.03e-1)" "unprognostic (7.75e-2)" "unprognostic (7.58e-2)" "unprognostic (1.96e-1)" "unprognostic (1.29e-1)" "potential prognostic unfavorable (1.64e-5)" "unprognostic (2.55e-1)" PRELID3A "C18orf43, FLJ31484, HFL-EDDG1, SLMO1" ENSG00000141391 "PRELI domain containing 3A" Q96N28 18 12407896-12432238 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 21.5;Bergmann glia: 30.0;Other brain neurons: 23.2;Retinal amacrine cells: 27.8;Retinal bipolar cells: 26.7;Retinal ganglion cells: 30.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.0" "Lineage enriched" "Detected in single" 4 "granulocytes: 3.0" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 2 "unprognostic (2.68e-2)" "unprognostic (4.50e-2)" "unprognostic (1.56e-2)" "unprognostic (4.42e-2)" "unprognostic (7.87e-2)" "unprognostic (2.09e-1)" "unprognostic (1.01e-2)" "unprognostic (2.79e-1)" "unprognostic (4.68e-3)" "potential prognostic unfavorable (5.65e-4)" "unprognostic (1.35e-3)" "unprognostic (1.02e-2)" "unprognostic (1.57e-2)" "unprognostic (3.50e-2)" "unprognostic (4.32e-2)" "unprognostic (1.92e-1)" "unprognostic (3.82e-2)" "unprognostic (5.80e-2)" "unprognostic (2.34e-3)" "unprognostic (3.90e-2)" "potential prognostic unfavorable (8.56e-4)" "unprognostic (3.19e-2)" "unprognostic (4.75e-2)" "unprognostic (2.45e-2)" "unprognostic (4.87e-2)" "unprognostic (1.03e-1)" "unprognostic (2.70e-1)" "unprognostic (7.26e-2)" "unprognostic (1.95e-3)" PRELID3B "C20orf45, dJ543J19.5, SLMO2" ENSG00000101166 "PRELI domain containing 3B" Q9Y3B1 20 59033145-59042809 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 617.5;Gastric progenitor cells: 176.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047721 Uncertain Approved Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 77: Intestine - Digestion" "Cluster 21: Non-specific - Metabolism" "Cluster 62: Non-specific - Plasma proteins" "Cluster 84: Apical squamous epithelium - Cornification" 4 Nucleoplasm "HPA047721: " "unprognostic (2.12e-1)" "unprognostic (2.01e-2)" "unprognostic (5.69e-3)" "unprognostic (3.78e-2)" "unprognostic (1.38e-1)" "unprognostic (2.93e-1)" "potential prognostic unfavorable (8.42e-4)" "unprognostic (3.32e-2)" "potential prognostic unfavorable (7.05e-4)" "unprognostic (2.70e-3)" "unprognostic (4.19e-2)" "unprognostic (7.99e-3)" "potential prognostic unfavorable (2.43e-4)" "unprognostic (8.46e-3)" "unprognostic (3.12e-2)" "unprognostic (1.48e-1)" "unprognostic (1.66e-1)" "unprognostic (3.83e-1)" "potential prognostic unfavorable (4.87e-4)" "unprognostic (1.28e-2)" "unprognostic (2.04e-2)" "unprognostic (7.03e-2)" "potential prognostic favorable (1.48e-4)" "unprognostic (3.03e-2)" "unprognostic (2.44e-1)" "unprognostic (5.34e-2)" "unprognostic (2.29e-1)" "unprognostic (1.02e-2)" "unprognostic (2.71e-1)" PRELP "prolargin, SLRR2A" ENSG00000188783 "Proline and arginine rich end leucine rich repeat protein" P51888 1 203475806-203491352 "Plasma proteins, Predicted secreted proteins" Heparin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 545.5" "Cell type enhanced" "Detected in many" "Fibroblasts: 473.2;Hepatic stellate cells: 219.5;Leydig cells: 90.7;Melanocytes: 292.2;Müller glia: 138.2;Ovarian stromal cells: 162.4;Pericytes: 92.2;Peritubular myoid cells: 199.9;Schwann cells: 146.4;Smooth muscle cells: 129.8;Vascular smooth muscle cells: 169.4" "Group enriched" "Detected in many" 14 "fibroblast: 376.0;pericyte: 443.8;vascular associated smooth muscle cell: 126.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.1" "Cancer enhanced" "Detected in some" "Brain cancer: 3.8;testis cancer: 4.8" "Adrenal gland - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Prostate - Smooth muscle cells, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 112.6" HPA059225 Uncertain "Endoplasmic reticulum,Plasma membrane" "Secreted to extracellular matrix" Other NA NA 250000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 11 "Endoplasmic reticulum" "Plasma membrane" "HPA059225: " "unprognostic (2.56e-2)" "unprognostic (3.32e-1)" "unprognostic (1.08e-1)" "unprognostic (1.51e-1)" "potential prognostic unfavorable (7.09e-4)" "unprognostic (1.02e-1)" "unprognostic (1.62e-1)" "potential prognostic unfavorable (2.71e-4)" "unprognostic (6.51e-2)" "unprognostic (2.46e-1)" "unprognostic (2.92e-1)" "unprognostic (6.15e-2)" "potential prognostic unfavorable (5.70e-7)" "unprognostic (2.34e-1)" "unprognostic (1.18e-2)" "unprognostic (5.23e-3)" "unprognostic (1.36e-1)" "unprognostic (7.68e-2)" "unprognostic (1.66e-1)" "unprognostic (2.69e-1)" "unprognostic (3.86e-2)" "unprognostic (2.96e-1)" "unprognostic (5.36e-3)" "unprognostic (1.82e-1)" "unprognostic (1.14e-3)" "unprognostic (7.05e-2)" "unprognostic (1.04e-3)" "unprognostic (1.73e-2)" "unprognostic (2.57e-1)" "unprognostic (8.48e-2)" "unprognostic (8.32e-2)" PREP ENSG00000085377 "Prolyl endopeptidase" P48147 6 105273218-105454062 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 184.2;Myonuclei: 184.4;Sertoli cells: 192.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025414, HPA031388, HPA031389, HPA031390" Supported Supported Cytosol NA NA 1500000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 53: Neurons - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 3 Cytosol "CAB025414: , HPA031388: , HPA031389: , HPA031390: " "unprognostic (1.86e-1)" "unprognostic (1.96e-2)" "unprognostic (1.72e-2)" "unprognostic (2.24e-2)" "unprognostic (7.39e-2)" "unprognostic (1.55e-2)" "unprognostic (1.59e-1)" "unprognostic (2.66e-2)" "unprognostic (1.65e-3)" "potential prognostic unfavorable (9.73e-4)" "unprognostic (2.62e-3)" "unprognostic (2.68e-1)" "unprognostic (5.38e-2)" "potential prognostic unfavorable (3.17e-5)" "unprognostic (3.15e-2)" "unprognostic (5.35e-2)" "unprognostic (2.24e-1)" "unprognostic (8.94e-2)" "unprognostic (8.03e-2)" "unprognostic (6.68e-2)" "unprognostic (7.54e-3)" "unprognostic (3.21e-2)" "unprognostic (7.81e-3)" "unprognostic (2.71e-1)" "unprognostic (6.78e-3)" "unprognostic (1.42e-1)" "unprognostic (8.15e-2)" "unprognostic (1.59e-1)" "unprognostic (5.05e-2)" "unprognostic (1.20e-1)" "unprognostic (2.65e-1)" PREPL KIAA0436 ENSG00000138078 "Prolyl endopeptidase like" Q4J6C6 2 44316281-44361862 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Brain inhibitory neurons: 295.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063238 Approved NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 27: Cerebellum - Synaptic function" "Cluster 14: Neurons - Synaptic function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 98: Neurons - Neurotransmission & signaling" 8 "HPA063238: " "unprognostic (3.04e-2)" "unprognostic (8.19e-3)" "unprognostic (4.41e-1)" "unprognostic (7.59e-2)" "unprognostic (1.67e-1)" "unprognostic (4.06e-2)" "unprognostic (4.46e-2)" "unprognostic (7.84e-2)" "unprognostic (1.25e-1)" "unprognostic (5.66e-3)" "validated prognostic favorable (4.60e-9)" "validated prognostic favorable (6.31e-4)" "unprognostic (2.09e-3)" "unprognostic (2.63e-2)" "unprognostic (7.75e-2)" "unprognostic (5.69e-2)" "unprognostic (3.28e-1)" "unprognostic (1.75e-1)" "unprognostic (2.80e-1)" "unprognostic (9.53e-2)" "unprognostic (4.23e-2)" "unprognostic (8.33e-2)" "unprognostic (5.57e-2)" "unprognostic (3.56e-2)" "unprognostic (4.53e-2)" "unprognostic (1.19e-1)" "unprognostic (2.52e-1)" "unprognostic (1.42e-1)" "unprognostic (1.74e-1)" "unprognostic (9.28e-2)" "unprognostic (2.89e-2)" PREX1 "KIAA1415, P-REX1" ENSG00000124126 "Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1" Q8TCU6 20 48624252-48827999 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 49.6" "Cell type enriched" "Detected in many" 4 "Neutrophils: 2623.3" "Cell type enhanced" "Detected in all" "Bergmann glia: 548.2;central nervous system macrophage: 683.9;leukocyte: 423.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Bone cancer: 56.6;breast cancer: 47.7" "Breast - Breast glandular cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001927 Supported Supported Vesicles,Cytosol NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 24: Neutrophils - Innate immunity signal integration" 13 "Vesicles, Cytosol" "HPA001927: " "unprognostic (7.87e-2)" "unprognostic (3.13e-2)" "unprognostic (2.00e-1)" "unprognostic (6.16e-2)" "unprognostic (1.24e-1)" "unprognostic (1.30e-1)" "unprognostic (9.55e-2)" "unprognostic (5.35e-2)" "unprognostic (1.75e-3)" "unprognostic (3.27e-1)" "potential prognostic favorable (2.09e-6)" "unprognostic (4.17e-3)" "unprognostic (3.13e-1)" "unprognostic (8.18e-2)" "unprognostic (7.63e-2)" "unprognostic (5.04e-3)" "unprognostic (7.91e-2)" "unprognostic (1.51e-2)" "unprognostic (1.09e-1)" "unprognostic (4.68e-2)" "unprognostic (5.99e-2)" "unprognostic (1.45e-1)" "unprognostic (5.14e-2)" "unprognostic (6.07e-2)" "unprognostic (1.16e-1)" "unprognostic (2.75e-2)" "unprognostic (2.42e-2)" "unprognostic (8.46e-2)" "unprognostic (1.17e-1)" "unprognostic (1.91e-1)" "unprognostic (1.25e-1)" PREX2 "DEP.2, DEPDC2, FLJ12987, P-REX2, PPP1R129" ENSG00000046889 "Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2" Q70Z35 8 67952046-68237032 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 1133.7;Bergmann glia: 1909.3;Ependymal cells: 559.0;Hematopoietic stem cells: 380.4;Müller glia: 256.8;Oligodendrocyte progenitor cells: 524.7;Oligodendrocytes: 356.6;Thyrotrophs: 370.0;Vascular endothelial cells: 444.6" "Cell type enhanced" "Detected in all" "astrocyte: 1101.8;Bergmann glia: 1960.0" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 7.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Kidney cancer: 7.9;ovarian cancer: 2.9;Uterine cancer: 4.6" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Liver - Vascular endothelial cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015234, HPA075956" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 3 "Endoplasmic reticulum" "HPA015234: , HPA075956: " "unprognostic (1.19e-1)" "unprognostic (6.27e-2)" "unprognostic (8.43e-3)" "unprognostic (3.79e-1)" "unprognostic (3.22e-3)" "unprognostic (8.44e-2)" "unprognostic (3.42e-1)" "unprognostic (1.66e-1)" "unprognostic (2.06e-1)" "unprognostic (2.74e-2)" "unprognostic (4.89e-1)" "unprognostic (1.35e-1)" "unprognostic (1.33e-1)" "unprognostic (1.58e-1)" "unprognostic (1.25e-3)" "unprognostic (2.08e-1)" "unprognostic (7.77e-2)" "unprognostic (1.64e-3)" PRF1 "HPLH2, P1, PFP" ENSG00000180644 "Perforin 1" P14222 10 70597348-70602759 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" Cytolysis "Cancer-related genes, Disease variant, Familial hemophagocytic lymphohistiocytosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 26.9;lung: 15.5;lymphoid tissue: 46.4" "Cell type enriched" "Detected in some" 5 "NK-cells: 737.8" "Cell type enriched" "Detected in some" 233 "leukocyte: 262.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 900.8;MAIT T-cell: 628.8;memory CD8 T-cell: 498.2;naive CD8 T-cell: 313.2;NK-cell: 657.0" "Group enriched" "Detected in all" 50 "NK-cells: 657.0;T-cells: 900.8" "Cancer enriched" "Detected in some" 7 "lymphoma: 61.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Lung - NK-cells (Lung), Minor Salivary Gland - T-cells, Pancreas - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Stomach - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002436, HPA037940" Approved Approved Cytosol "Intracellular and membrane" Other NA NA 480000 "Cluster 15: NK-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 8: Immune cells - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 32 Cytosol "CAB002436: , HPA037940: " "unprognostic (6.99e-2)" "unprognostic (5.42e-3)" "unprognostic (4.69e-2)" "unprognostic (4.06e-2)" "unprognostic (1.01e-1)" "unprognostic (1.42e-1)" "unprognostic (3.46e-2)" "unprognostic (5.96e-2)" "potential prognostic favorable (4.55e-4)" "unprognostic (2.24e-1)" "unprognostic (2.60e-2)" "unprognostic (5.18e-2)" "unprognostic (7.16e-3)" "unprognostic (1.71e-2)" "unprognostic (4.57e-2)" "unprognostic (1.47e-1)" "unprognostic (9.53e-2)" "unprognostic (8.05e-2)" "unprognostic (1.95e-1)" "unprognostic (5.51e-3)" "unprognostic (3.49e-2)" "unprognostic (1.86e-1)" "unprognostic (7.95e-2)" "unprognostic (1.54e-1)" "unprognostic (1.01e-1)" "unprognostic (1.89e-1)" "unprognostic (1.55e-3)" "unprognostic (6.26e-2)" "unprognostic (2.88e-1)" "unprognostic (2.60e-2)" "unprognostic (1.79e-1)" PRG2 "BMPG, MBP, proMBP" ENSG00000186652 "Proteoglycan 2, pro eosinophil major basic protein" P13727 11 57386780-57390650 "FDA approved drug targets, Plasma proteins, Predicted secreted proteins" Immunity "Antibiotic, Antimicrobial, Heparin-binding" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "placenta: 2458.0" "Cell type enriched" "Detected in some" 39 "Extravillous trophoblasts: 126.0" "Cell type enhanced" "Detected in single" "pericyte: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 36 "basophil: 7.3" "Lineage enriched" "Detected in single" 74 "granulocytes: 7.3" "Cancer enriched" "Detected in some" 47 "Leukemia: 370.8" "Lung - Neutrophils_1, Spleen - Neutrophils_1" "Not detected" "Not detected" "Not detected" "Not detected" HPA038515 Supported "Secreted in female reproductive system" Immunity NA NA 63000000 "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 49: HMC-1 - Innate immune response" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 146 "HPA038515: " "unprognostic (1.38e-1)" "potential prognostic favorable (7.58e-5)" PRG3 "MBP2, MBPH" ENSG00000156575 "Proteoglycan 3, pro eosinophil major basic protein 2" Q9Y2Y8 11 57376769-57381150 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "bone marrow: 45.8" "Cell type enriched" "Detected in single" 19 "Monocyte progenitors: 13.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 27 "Leukemia: 2.7" "Lung - Neutrophils_1, Spleen - Neutrophils_1" "Not detected" "Not detected" "Not detected" "Not detected" HPA064183 Enhanced "Secreted in other tissues" "No annotated function" NA NA 490000 "Cluster 15: Bone marrow - Innate immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 27: Non-specific - Cell proliferation" 19 "HPA064183: " PRG4 "bG174L6.2, CACP, FLJ32635, HAPO, JCAP, MSF, SZP" ENSG00000116690 "Proteoglycan 4" Q92954 1 186296279-186314567 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 87.0;liver: 173.7" "Cell type enhanced" "Detected in some" "Epicardial cells: 1071.1;Fibroblasts: 113.1;Hepatocytes: 373.8;Mesothelial cells: 1833.4" "Cell type enriched" "Detected in some" 5 "fibroblast: 6.2" "Cancer enriched" "Detected in many" 4 "Liver Hepatocellular Carcinoma (TCGA): 52.6" "Region enriched" "Detected in some" 8 "hypothalamus: 66.4" "Immune cell enriched" "Detected in single" 5 "T-reg: 1.2" "Lineage enriched" "Detected in single" 12 "T-cells: 1.2" "Cancer enriched" "Detected in some" 18 "Rhabdoid: 33.0" "Adipose visceral - Mesothelial cells, Liver - Hepatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" CAB054258 Supported "Secreted to extracellular matrix" "No annotated function" NA NA 900000000 "Cluster 16: Non-specific - Cell proliferation" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" "CAB054258: " "unprognostic (1.82e-1)" "unprognostic (1.40e-2)" "unprognostic (1.57e-1)" "unprognostic (1.36e-3)" "unprognostic (9.16e-2)" "unprognostic (1.40e-2)" "unprognostic (1.74e-3)" "unprognostic (1.77e-1)" "unprognostic (3.44e-1)" "unprognostic (1.58e-1)" "unprognostic (8.33e-2)" "unprognostic (2.84e-2)" "unprognostic (2.93e-3)" PRH1 Pa ENSG00000231887 "Proline rich protein HaeIII subfamily 1" 12 10824960-11171608 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 14 "salivary gland: 222.9;testis: 56.4" "Cell type enhanced" "Detected in many" "Early spermatids: 560.2;Late spermatids: 2932.2;Neutrophils: 598.1;Salivary acinar cells: 12179.7;Salivary myoepithelial cells: 3566.1" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pituitary gland - Gonadotropes, Testis - Late spermatids" NA NA "Cluster 82: Salivary gland - Secretion" "Cluster 53: Neurons - Mixed function" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 38: Secretory epithelial cells - Exocrine secretion" "unprognostic (1.18e-1)" "unprognostic (1.68e-1)" PRH2 Pr ENSG00000134551 "Proline rich protein HaeIII subfamily 2" P02810 12 10929236-10934845 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 904 "salivary gland: 21601.6" "Cell type enriched" "Detected in some" 4 "Salivary acinar cells: 7506.4" "Cancer enriched" "Detected in single" 6 "Head and Neck Squamous Cell Carcinoma (TCGA): 4.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Secreted to digestive system" "No annotated function" NA NA 7300000 "Cluster 82: Salivary gland - Secretion" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 1 "unprognostic (2.87e-1)" "unprognostic (1.45e-1)" "unprognostic (3.70e-1)" "unprognostic (2.05e-1)" "unprognostic (1.24e-1)" PRICKLE1 "EPM1B, FLJ31937, RILP" ENSG00000139174 "Prickle planar cell polarity protein 1" Q96MT3 12 42456757-42590355 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 241.7;Brain inhibitory neurons: 174.7;Corticotrophs: 245.3;Endometrial stromal cells: 297.2;Fibro-adipogenic progenitors: 570.6;Oligodendrocyte progenitor cells: 209.0;Oligodendrocytes: 186.8;Retinal bipolar cells: 228.1;Retinal ganglion cells: 413.3;Salivary ionocytes: 174.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 11.6" "Group enriched" "Detected in many" 4 "B-cells: 11.6;granulocytes: 4.0" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Testis - Early spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001379 Approved Uncertain "Nucleoplasm,Basal body,Cytosol" NA NA "Cluster 18: Non-specific - Translation" "Cluster 13: Lung - Secretion" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 4 Nucleoplasm "Basal body, Cytosol" "HPA001379: " "unprognostic (1.81e-1)" "unprognostic (1.71e-1)" "unprognostic (3.05e-1)" "unprognostic (8.03e-2)" "unprognostic (1.27e-2)" "unprognostic (7.30e-2)" "unprognostic (1.34e-1)" "unprognostic (3.37e-2)" "unprognostic (5.93e-2)" "unprognostic (9.90e-3)" "potential prognostic favorable (9.00e-4)" "unprognostic (3.89e-3)" "potential prognostic favorable (6.75e-4)" "unprognostic (9.24e-3)" "unprognostic (1.56e-2)" "unprognostic (2.03e-2)" "unprognostic (3.41e-2)" "unprognostic (8.81e-2)" "unprognostic (2.28e-2)" "unprognostic (1.13e-3)" "unprognostic (7.77e-2)" "unprognostic (9.91e-2)" "unprognostic (1.40e-1)" "unprognostic (5.53e-2)" "unprognostic (8.60e-3)" "unprognostic (6.48e-2)" "potential prognostic unfavorable (1.10e-4)" "unprognostic (1.61e-1)" "unprognostic (8.10e-2)" "unprognostic (2.71e-1)" PRICKLE2 DKFZp686D143 ENSG00000163637 "Prickle planar cell polarity protein 2" Q7Z3G6 3 64092236-64445476 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Epilepsy, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 639.9;Choroid plexus epithelial cells: 1443.5;Distal convoluted tubule cells: 471.7;Ependymal cells: 601.5;Pituicytes/FSCs: 1663.4;Respiratory ciliated cells: 488.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Liver - Vascular endothelial cells, Minor Salivary Gland - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035493 Approved "Golgi apparatus,Vesicles" NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 51: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" "Golgi apparatus" Vesicles "HPA035493: " "unprognostic (8.00e-2)" "unprognostic (2.72e-1)" "unprognostic (2.92e-1)" "unprognostic (1.51e-1)" "unprognostic (3.49e-1)" "unprognostic (1.79e-1)" "unprognostic (2.15e-1)" "unprognostic (1.93e-1)" "unprognostic (6.10e-3)" "potential prognostic favorable (5.01e-6)" "unprognostic (2.57e-3)" "unprognostic (4.74e-2)" "unprognostic (2.74e-2)" "unprognostic (6.85e-3)" "unprognostic (9.31e-2)" "unprognostic (1.16e-1)" "unprognostic (7.27e-2)" "unprognostic (8.86e-2)" "unprognostic (3.49e-2)" "unprognostic (5.96e-2)" "unprognostic (1.15e-1)" "unprognostic (1.30e-1)" "unprognostic (2.59e-2)" "unprognostic (6.86e-2)" "unprognostic (1.94e-1)" "unprognostic (7.17e-3)" "unprognostic (6.28e-2)" "unprognostic (1.06e-2)" "unprognostic (7.70e-2)" PRICKLE3 LMO6 ENSG00000012211 "Prickle planar cell polarity protein 3" O43900 X 49174802-49186528 "Disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Developmental protein" "Disease variant, Leber hereditary optic neuropathy, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Early spermatids: 98.5;Late spermatids: 185.7" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 7.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (other)" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA000998 Uncertain NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 12: Non-specific - Vasculature" "Cluster 36: Non-specific - mRNA processing" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 19 "HPA000998: " "unprognostic (3.31e-1)" "unprognostic (1.05e-2)" "unprognostic (7.11e-2)" "unprognostic (1.20e-1)" "unprognostic (2.86e-2)" "unprognostic (1.19e-1)" "unprognostic (1.15e-2)" "potential prognostic unfavorable (1.36e-5)" "unprognostic (1.73e-1)" "unprognostic (1.37e-1)" "unprognostic (2.18e-1)" "potential prognostic unfavorable (8.60e-4)" "unprognostic (3.50e-2)" "unprognostic (3.70e-2)" "unprognostic (1.15e-1)" "unprognostic (5.49e-2)" "unprognostic (7.31e-3)" "unprognostic (7.06e-2)" "unprognostic (1.24e-1)" "unprognostic (7.50e-2)" "unprognostic (7.63e-2)" "unprognostic (5.03e-2)" "unprognostic (1.15e-1)" "unprognostic (4.58e-2)" "unprognostic (3.53e-3)" "unprognostic (7.40e-2)" "unprognostic (1.02e-1)" "unprognostic (7.70e-3)" "unprognostic (1.43e-1)" "unprognostic (5.52e-2)" "unprognostic (1.76e-2)" PRICKLE4 "C6orf49, DKFZp761H221, OEBT" ENSG00000278224 "Prickle planar cell polarity protein 4" Q2TBC4 6 41780782-41787452 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 1.4;Ependymal cells: 1.1" "Cell type enriched" "Detected in some" 4 "endothelial cell: 5.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031240, HPA055593" Approved Approved "Mitotic spindle,Centriolar satellite" Yes NA "Cluster 5: Spleen - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 104: Brain endothelial cells - Blood brain barrier" 1 "Centriolar satellite" "Mitotic spindle" "HPA031240: , HPA055593: " "unprognostic (2.82e-3)" "unprognostic (1.33e-1)" "unprognostic (1.18e-3)" "unprognostic (1.36e-1)" "unprognostic (8.62e-2)" "potential prognostic favorable (1.41e-4)" "unprognostic (3.84e-2)" "unprognostic (4.36e-3)" "unprognostic (1.44e-1)" "unprognostic (8.44e-3)" "unprognostic (2.47e-1)" "unprognostic (1.32e-1)" "unprognostic (1.19e-1)" "unprognostic (5.54e-3)" "unprognostic (1.04e-1)" "unprognostic (2.12e-1)" "unprognostic (2.26e-1)" PRIM1 ENSG00000198056 "DNA primase subunit 1" P49642 12 56730438-56752374 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA replication, Transcription" "Nucleotidyltransferase, Transferase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 26.4" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 83.7;Early primary spermatocytes: 165.1;Erythrocyte progenitors: 66.8;Megakaryocyte progenitors: 42.8;Oocytes: 41.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040010 Uncertain NA Yes "Cluster 3: Non-specific - Nuclear processes" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 2: Neurons - Nucleosome" "Cluster 38: Non-specific - Transcription" "Cluster 3: Early primary spermatocytes - Early meiosis" 21 "HPA040010: " "unprognostic (5.68e-3)" "potential prognostic unfavorable (2.28e-4)" "unprognostic (2.63e-1)" "unprognostic (1.12e-2)" "unprognostic (4.12e-1)" "unprognostic (5.75e-2)" "unprognostic (4.44e-2)" "unprognostic (9.65e-2)" "unprognostic (6.00e-2)" "unprognostic (5.51e-3)" "potential prognostic favorable (1.44e-4)" "unprognostic (1.22e-1)" "unprognostic (2.61e-1)" "validated prognostic unfavorable (2.45e-6)" "validated prognostic unfavorable (4.47e-6)" "unprognostic (5.39e-3)" "unprognostic (4.23e-3)" "unprognostic (4.11e-2)" "unprognostic (1.96e-2)" "unprognostic (8.90e-2)" "unprognostic (1.39e-1)" "unprognostic (6.79e-2)" "unprognostic (1.08e-3)" "unprognostic (2.07e-1)" "unprognostic (2.14e-3)" "unprognostic (1.19e-1)" "unprognostic (1.60e-2)" "unprognostic (3.52e-1)" "unprognostic (2.62e-1)" "unprognostic (9.17e-2)" "unprognostic (6.30e-2)" PRIM2 PRIM2A ENSG00000146143 "DNA primase subunit 2" P49643 6 57314805-57646850 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "DNA replication" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "prostate: 30.3" "Cell type enhanced" "Detected in many" "Prostatic glandular cells: 479.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Prostate - Prostate glandular cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046566 Supported Nucleoplasm NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 20 Nucleoplasm "HPA046566: " "unprognostic (1.44e-2)" "unprognostic (9.82e-2)" "unprognostic (9.19e-3)" "unprognostic (5.51e-2)" "unprognostic (1.32e-1)" "unprognostic (5.40e-2)" "unprognostic (2.45e-1)" "unprognostic (2.05e-3)" "unprognostic (4.29e-1)" "potential prognostic unfavorable (1.03e-7)" "potential prognostic favorable (2.71e-4)" "unprognostic (1.74e-1)" "unprognostic (8.48e-3)" "validated prognostic unfavorable (2.28e-5)" "validated prognostic unfavorable (1.38e-5)" "unprognostic (2.49e-2)" "potential prognostic unfavorable (9.59e-4)" "unprognostic (2.29e-3)" "unprognostic (2.67e-2)" "potential prognostic favorable (6.95e-4)" "unprognostic (1.28e-1)" "unprognostic (3.53e-3)" "unprognostic (2.11e-3)" "unprognostic (2.68e-1)" "unprognostic (2.75e-3)" "unprognostic (1.40e-2)" "unprognostic (2.85e-3)" "unprognostic (7.27e-2)" "unprognostic (1.80e-1)" "unprognostic (8.05e-2)" "unprognostic (7.57e-2)" PRIMA1 PRIMA ENSG00000175785 "Proline rich membrane anchor 1" Q86XR5 14 93718298-93788485 "Predicted membrane proteins" "Neurotransmitter degradation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 45.4;intestine: 52.7" "Cell type enhanced" "Detected in some" "Bergmann glia: 18.0;Ependymal cells: 21.7;Loop of henle epithelial cells: 5.7;Oligodendrocytes: 86.8;Other brain neurons: 29.8;Schwann cells: 10.6" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 48.2;oligodendrocyte: 130.9" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 6.9;Ovary Serous Cystadenocarcinoma (TCGA): 7.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Neuroblastoma: 6.1" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Kidney - Fibroblasts, Spleen - Smooth muscle cells" "Region enhanced" "Detected in many" "basal ganglia: 18.2" "Low region specificity" "Detected in all" "HPA046671, HPA060047" Approved Approved "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 30: White matter - Myelination" "Cluster 69: Skin cancer - ECM organization" "Cluster 80: Oligodendrocytes - Myelination" "Plasma membrane" "Nucleoli, Cytosol" "HPA046671: , HPA060047: " "unprognostic (3.59e-1)" "unprognostic (8.26e-2)" "unprognostic (2.66e-2)" "unprognostic (1.59e-1)" "unprognostic (6.10e-2)" "unprognostic (5.25e-2)" "unprognostic (1.14e-1)" "unprognostic (7.97e-3)" "unprognostic (1.36e-2)" "unprognostic (1.95e-1)" "unprognostic (5.68e-2)" "unprognostic (1.16e-1)" "potential prognostic unfavorable (7.64e-4)" "unprognostic (1.80e-1)" "unprognostic (1.39e-1)" PRIMPOL "CCDC111, FLJ33167" ENSG00000164306 "Primase and DNA directed polymerase" Q96LW4 4 184649667-184694963 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription" "DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 24.1" "Lineage enriched" "Detected in all" 4 "granulocytes: 24.1" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054372 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 25: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 70: Intestinal goblet cells - Mucin production" 9 Cytosol Nucleoplasm "HPA054372: " "unprognostic (1.05e-1)" "unprognostic (1.33e-1)" "unprognostic (7.44e-2)" "unprognostic (2.59e-1)" "unprognostic (2.03e-2)" "unprognostic (6.36e-3)" "unprognostic (1.67e-1)" "unprognostic (8.17e-2)" "unprognostic (2.45e-2)" "potential prognostic favorable (5.03e-5)" "unprognostic (3.35e-3)" "unprognostic (5.77e-2)" "unprognostic (7.82e-2)" "unprognostic (5.48e-3)" "unprognostic (2.02e-1)" "unprognostic (1.21e-1)" "unprognostic (1.61e-1)" "unprognostic (4.49e-2)" "unprognostic (6.80e-3)" "unprognostic (1.92e-1)" "unprognostic (6.89e-3)" "unprognostic (2.53e-1)" "unprognostic (7.53e-2)" "unprognostic (1.15e-1)" "unprognostic (5.24e-2)" "unprognostic (1.56e-1)" "unprognostic (5.87e-2)" "unprognostic (4.49e-2)" "unprognostic (1.20e-1)" PRKAA1 AMPKa1 ENSG00000132356 "Protein kinase AMP-activated catalytic subunit alpha 1" Q13131 5 40759389-40798374 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Autophagy, Biological rhythms, Cholesterol biosynthesis, Cholesterol metabolism, Fatty acid biosynthesis, Fatty acid metabolism, Host-virus interaction, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism, Transcription, Transcription regulation, Wnt signaling pathway" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 276.6;Late primary spermatocytes: 263.0;Late spermatids: 707.5;Neutrophil progenitors: 279.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005050, HPA035409, HPA064946" Supported Supported "Nuclear speckles,Primary cilium,Basal body,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 57: Testis - Spermatogenesis" "Cluster 45: Non-specific - Mixed function" "Cluster 29: Non-specific - Unknown function" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 90 "Nuclear speckles" "Primary cilium, Basal body, Cytosol" "CAB005050: , HPA035409: , HPA064946: " "unprognostic (1.57e-2)" "unprognostic (2.22e-1)" "unprognostic (1.87e-2)" "unprognostic (3.18e-3)" "unprognostic (2.10e-1)" "unprognostic (1.90e-3)" "unprognostic (1.61e-1)" "unprognostic (4.85e-2)" "unprognostic (1.38e-1)" "unprognostic (8.57e-3)" "potential prognostic favorable (1.15e-6)" "unprognostic (1.99e-2)" "unprognostic (2.05e-1)" "unprognostic (3.97e-2)" "unprognostic (1.34e-1)" "unprognostic (2.31e-1)" "unprognostic (1.46e-2)" "unprognostic (3.66e-2)" "unprognostic (5.75e-2)" "unprognostic (4.68e-2)" "potential prognostic unfavorable (6.73e-5)" "unprognostic (4.57e-3)" "unprognostic (1.47e-1)" "unprognostic (2.02e-1)" "unprognostic (1.04e-2)" "unprognostic (1.23e-1)" "unprognostic (6.38e-2)" "unprognostic (2.27e-1)" "unprognostic (2.46e-1)" "unprognostic (2.93e-2)" "unprognostic (3.12e-2)" PRKAA2 "AMPK, AMPKa2, PRKAA" ENSG00000162409 "Protein kinase AMP-activated catalytic subunit alpha 2" P54646 1 56645314-56715335 "Enzymes, FDA approved drug targets, Predicted membrane proteins, Transporters" "Autophagy, Biological rhythms, Cholesterol biosynthesis, Cholesterol metabolism, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism, Transcription, Transcription regulation, Wnt signaling pathway" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 38.2;skeletal muscle: 36.1;tongue: 34.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 389.7;Distal convoluted tubule cells: 221.7;Myonuclei: 481.8;Renal collecting duct intercalated cells: 336.1;Renal connecting tubule cells: 198.8;Rod photoreceptor cells: 213.5;Thymic myoid cells: 243.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 9.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Cardiomyocytes, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044540 Approved Supported "Nucleoplasm,Nuclear speckles,Golgi apparatus,Basal body,Cytosol" NA NA "Cluster 41: Striated muscle - Muscle contraction" "Cluster 23: Choroid plexus - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 120 "Nuclear speckles" "Nucleoplasm, Golgi apparatus, Basal body, Cytosol" "HPA044540: " "unprognostic (2.74e-3)" "unprognostic (1.34e-1)" "unprognostic (6.14e-3)" "unprognostic (1.48e-2)" "unprognostic (2.40e-2)" "unprognostic (2.50e-2)" "unprognostic (2.15e-1)" "potential prognostic favorable (4.38e-10)" "unprognostic (1.83e-3)" "unprognostic (4.97e-2)" "potential prognostic unfavorable (2.80e-4)" "unprognostic (2.72e-2)" "unprognostic (1.59e-2)" "unprognostic (6.89e-2)" "unprognostic (5.35e-3)" "unprognostic (4.52e-2)" "unprognostic (5.14e-2)" "unprognostic (3.67e-2)" "unprognostic (1.73e-1)" "unprognostic (2.20e-1)" "unprognostic (1.11e-1)" "unprognostic (2.69e-2)" "unprognostic (8.31e-3)" "unprognostic (3.68e-2)" "unprognostic (6.88e-2)" PRKAB1 ENSG00000111725 "Protein kinase AMP-activated non-catalytic subunit beta 1" Q9Y478 12 119667864-119681624 "FDA approved drug targets, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 85.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Spleen - Endothelial cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004247, CAB005058" Enhanced Approved "Nucleoplasm,Primary cilium transition zone,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 30: White matter - Myelination" "Cluster 38: Non-specific - Transcription" "Cluster 84: Apical squamous epithelium - Cornification" 31 Cytosol "Nucleoplasm, Primary cilium transition zone" "CAB005058: , HPA004247: " "unprognostic (1.13e-1)" "unprognostic (2.51e-1)" "unprognostic (2.16e-1)" "unprognostic (1.50e-2)" "unprognostic (1.18e-2)" "unprognostic (1.19e-1)" "unprognostic (2.25e-1)" "unprognostic (9.11e-3)" "unprognostic (1.43e-1)" "unprognostic (2.49e-1)" "validated prognostic favorable (3.45e-9)" "validated prognostic favorable (1.01e-4)" "unprognostic (6.14e-2)" "unprognostic (3.53e-2)" "unprognostic (4.53e-3)" "unprognostic (6.04e-3)" "unprognostic (5.06e-2)" "unprognostic (6.40e-3)" "unprognostic (1.94e-2)" "unprognostic (1.33e-1)" "unprognostic (1.01e-1)" "unprognostic (4.80e-1)" "unprognostic (6.02e-2)" "unprognostic (1.01e-1)" "unprognostic (3.65e-2)" "unprognostic (1.36e-1)" "unprognostic (2.30e-1)" "unprognostic (5.38e-2)" "unprognostic (1.02e-1)" "unprognostic (1.21e-1)" "unprognostic (1.25e-1)" PRKAB2 ENSG00000131791 "Protein kinase AMP-activated non-catalytic subunit beta 2" O43741 1 147155106-147172550 "FDA approved drug targets, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 91.1;tongue: 97.0" "Cell type enhanced" "Detected in many" "Platelets: 101.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044342 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 41: Basophils - Unknown function" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 37: Neurons - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 1: Enterocytes - Absorption and Digestion" 221 Nucleoplasm Cytosol "HPA044342: " "unprognostic (5.31e-2)" "potential prognostic unfavorable (7.91e-4)" "unprognostic (5.21e-2)" "unprognostic (3.02e-2)" "unprognostic (7.53e-2)" "unprognostic (1.09e-2)" "unprognostic (9.12e-2)" "unprognostic (1.58e-2)" "unprognostic (4.30e-3)" "unprognostic (1.32e-2)" "unprognostic (3.76e-3)" "potential prognostic favorable (2.28e-4)" "unprognostic (2.25e-2)" "unprognostic (7.14e-2)" "unprognostic (2.75e-1)" "unprognostic (2.51e-2)" "unprognostic (8.69e-2)" "unprognostic (3.06e-1)" "unprognostic (2.25e-1)" "unprognostic (2.92e-2)" "unprognostic (2.13e-2)" "unprognostic (2.37e-1)" "unprognostic (1.31e-1)" "unprognostic (3.30e-1)" "unprognostic (1.60e-2)" "unprognostic (2.04e-1)" "unprognostic (3.60e-1)" "unprognostic (7.91e-2)" "unprognostic (4.09e-1)" "potential prognostic unfavorable (4.39e-4)" "unprognostic (6.47e-2)" PRKACA PKACa ENSG00000072062 "Protein kinase cAMP-activated catalytic subunit alpha" P17612 19 14091688-14118084 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Cushing syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 276.2" "Cell type enhanced" "Detected in many" "Astrocytes: 23.8;Bergmann glia: 25.2;Brain excitatory neurons: 34.9;Brain inhibitory neurons: 32.0;Choroid plexus epithelial cells: 18.6;Distal convoluted tubule cells: 21.8;Ependymal cells: 20.2;Loop of henle epithelial cells: 16.5;Microglia: 36.8;Oligodendrocyte progenitor cells: 21.7;Oligodendrocytes: 20.8;Other brain neurons: 42.7;Podocytes: 16.3;Proximal tubule cells: 17.2;Renal collecting duct intercalated cells: 18.7;Renal collecting duct principal cells: 18.9;Renal connecting tubule cells: 19.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Minor Salivary Gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010361, HPA071185" Approved Uncertain "Microtubules,Cytokinetic bridge,Primary cilium,Basal body,Cytosol" Yes NA 370000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 24: Non-specific - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 102: Non-specific - Mixed function" 158 Cytosol "Microtubules, Cytokinetic bridge, Primary cilium, Basal body" "CAB010361: , HPA071185: " "unprognostic (1.50e-2)" "unprognostic (6.82e-2)" "unprognostic (4.41e-2)" "unprognostic (3.96e-2)" "unprognostic (2.73e-1)" "unprognostic (4.54e-2)" "unprognostic (3.02e-2)" "unprognostic (2.00e-2)" "unprognostic (6.14e-2)" "unprognostic (1.30e-1)" "unprognostic (6.07e-2)" "unprognostic (1.17e-1)" "unprognostic (5.16e-2)" "unprognostic (3.18e-1)" "unprognostic (6.08e-2)" "unprognostic (1.39e-1)" "unprognostic (1.52e-1)" "potential prognostic favorable (8.02e-4)" "unprognostic (3.76e-1)" "unprognostic (2.41e-1)" "unprognostic (3.61e-2)" "potential prognostic favorable (9.59e-4)" "unprognostic (7.68e-2)" "unprognostic (2.50e-1)" "unprognostic (1.16e-2)" "unprognostic (1.15e-1)" "unprognostic (5.52e-2)" "unprognostic (2.70e-1)" "unprognostic (2.36e-2)" "unprognostic (6.54e-2)" "unprognostic (2.25e-1)" PRKACB PKACb ENSG00000142875 "Protein kinase cAMP-activated catalytic subunit beta" P22694 1 84078062-84238498 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 178.7" "Cell type enhanced" "Detected in all" "Brain inhibitory neurons: 439.1;Cone photoreceptor cells: 449.2;Corticotrophs: 416.4;Hematopoietic stem cells: 448.3;Megakaryocyte-Erythroid progenitors: 474.2;Oligodendrocytes: 493.4;Rod photoreceptor cells: 494.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010363, HPA029754, HPA071185" Approved Supported "Microtubules,Cytokinetic bridge,Primary cilium,Basal body,Cytosol" Yes NA 390000 "Cluster 1: T-cells - Unknown function" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 34: Non-specific - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 34 Cytosol "Microtubules, Cytokinetic bridge, Primary cilium, Basal body" "CAB010363: , HPA029754: , HPA071185: " "unprognostic (2.87e-3)" "unprognostic (2.61e-1)" "unprognostic (3.41e-1)" "unprognostic (2.36e-2)" "unprognostic (1.04e-1)" "unprognostic (9.23e-2)" "unprognostic (8.89e-2)" "unprognostic (1.87e-1)" "unprognostic (1.86e-1)" "unprognostic (4.57e-2)" "potential prognostic favorable (8.82e-8)" "unprognostic (2.34e-3)" "unprognostic (4.79e-2)" "potential prognostic unfavorable (6.48e-5)" "unprognostic (9.70e-2)" "unprognostic (3.40e-2)" "unprognostic (2.40e-2)" "unprognostic (2.23e-1)" "unprognostic (4.68e-2)" "unprognostic (6.07e-2)" "unprognostic (8.26e-2)" "unprognostic (2.64e-1)" "unprognostic (3.86e-2)" "unprognostic (1.35e-1)" "unprognostic (1.80e-2)" "unprognostic (1.22e-1)" "unprognostic (6.87e-2)" "unprognostic (1.60e-1)" "unprognostic (8.47e-2)" "unprognostic (1.13e-2)" "unprognostic (7.55e-2)" PRKACG PKACg ENSG00000165059 "Protein kinase cAMP-activated catalytic subunit gamma" P22612 9 69012504-69014113 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 230 "testis: 23.0" "Group enriched" "Detected in some" 20 "Early spermatids: 72.1;Late primary spermatocytes: 119.3;Late spermatids: 119.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "CAB004530, HPA071185" Supported Approved "Microtubules,Cytokinetic bridge,Primary cilium,Basal body,Cytosol" Yes NA "Cluster 23: Testis - Spermatogenesis" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 20 Cytosol "Microtubules, Cytokinetic bridge, Primary cilium, Basal body" "CAB004530: , HPA071185: " PRKAG1 ENSG00000181929 "Protein kinase AMP-activated non-catalytic subunit gamma 1" P54619 12 49002274-49018807 "FDA approved drug targets, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 30.1;Bergmann glia: 34.6;Brain excitatory neurons: 31.2;Brain inhibitory neurons: 31.4;Choroid plexus epithelial cells: 40.7;Distal convoluted tubule cells: 29.2;Ependymal cells: 24.3;Loop of henle epithelial cells: 26.3;Microglia: 34.9;Oligodendrocyte progenitor cells: 27.6;Oligodendrocytes: 30.3;Other brain neurons: 36.5;Papillary tip epithelial cells: 23.9;Podocytes: 32.0;Proximal tubule cells: 31.7;Renal collecting duct intercalated cells: 37.6;Renal collecting duct principal cells: 25.3;Renal connecting tubule cells: 25.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077805 Approved "Nucleoplasm,Nuclear bodies,Basal body,Cytosol" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 16: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 102: Non-specific - Mixed function" 49 "Nuclear bodies, Cytosol" "Nucleoplasm, Basal body" "HPA077805: " "unprognostic (1.36e-1)" "unprognostic (6.19e-3)" "unprognostic (1.38e-2)" "unprognostic (9.58e-3)" "unprognostic (1.01e-1)" "unprognostic (2.86e-1)" "unprognostic (2.16e-1)" "unprognostic (2.67e-1)" "unprognostic (6.75e-3)" "unprognostic (2.08e-2)" "potential prognostic favorable (2.47e-8)" "unprognostic (1.91e-1)" "unprognostic (6.83e-3)" "validated prognostic unfavorable (5.93e-7)" "validated prognostic unfavorable (5.40e-4)" "unprognostic (1.50e-2)" "unprognostic (1.63e-1)" "unprognostic (9.60e-2)" "unprognostic (2.72e-1)" "unprognostic (9.15e-2)" "unprognostic (5.53e-2)" "unprognostic (6.99e-2)" "unprognostic (1.21e-1)" "unprognostic (2.49e-1)" "unprognostic (2.39e-1)" "unprognostic (2.87e-2)" "unprognostic (5.71e-3)" "unprognostic (9.87e-2)" "unprognostic (4.34e-2)" "unprognostic (1.39e-1)" "unprognostic (7.84e-3)" PRKAG2 "AAKG, AAKG2, CMH6, H91620p, WPWS" ENSG00000106617 "Protein kinase AMP-activated non-catalytic subunit gamma 2" Q9UGJ0 7 151556124-151877125 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Cardiomyopathy, Disease variant, FDA approved drug targets, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 122.3" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 480.1;monocytes: 516.5;Prostatic glandular cells: 520.5;Renal collecting duct principal cells: 742.2;Renal connecting tubule cells: 762.5" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 69.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004246, CAB018641" Uncertain Approved Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 35: Non-specific - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 9 Nucleoplasm "CAB018641: , HPA004246: " "unprognostic (6.14e-2)" "unprognostic (2.92e-1)" "unprognostic (1.59e-2)" "unprognostic (2.46e-2)" "unprognostic (6.06e-3)" "unprognostic (2.50e-1)" "unprognostic (3.90e-1)" "unprognostic (2.55e-2)" "unprognostic (2.12e-3)" "unprognostic (1.49e-1)" "potential prognostic favorable (3.99e-5)" "unprognostic (4.92e-2)" "potential prognostic unfavorable (1.91e-4)" "unprognostic (1.44e-1)" "unprognostic (7.69e-3)" "unprognostic (2.97e-1)" "unprognostic (2.17e-1)" "unprognostic (7.02e-2)" "unprognostic (1.17e-1)" "unprognostic (1.09e-1)" "unprognostic (1.68e-1)" "unprognostic (1.59e-1)" "unprognostic (9.16e-2)" "unprognostic (8.92e-2)" "unprognostic (3.05e-1)" "potential prognostic unfavorable (4.35e-4)" "unprognostic (2.14e-1)" "unprognostic (3.16e-2)" "unprognostic (4.70e-2)" "unprognostic (1.74e-2)" "unprognostic (1.33e-1)" PRKAG3 ENSG00000115592 "Protein kinase AMP-activated non-catalytic subunit gamma 3" Q9UGI9 2 218822308-218832086 "FDA approved drug targets, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "skeletal muscle: 78.0" "Group enriched" "Detected in some" 8 "Myonuclei: 50.4;Thymic myoid cells: 29.9" "Cell type enriched" "Detected in single" 6 "medium spiny neuron: 1.9" "Not detected" "Not detected" "Region enhanced" "Detected in some" "basal ganglia: 3.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA076218 Approved Nucleoplasm,Mitochondria NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 33: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 30 Mitochondria Nucleoplasm "HPA076218: " PRKAR1A "CNC1, PRKAR1, TSE1" ENSG00000108946 "Protein kinase cAMP-dependent type I regulatory subunit alpha" P10644 17 68511780-68551319 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Cushing syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 550.6;Neutrophils: 469.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019378, HPA049979" Approved Approved Cytosol NA NA 2100000 "Cluster 28: Neutrophils - Unknown function" "Cluster 35: Non-specific - Mixed function" "Cluster 27: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 17: Non-specific - RNA processing" 67 Cytosol "CAB019378: , HPA049979: " "unprognostic (2.32e-1)" "unprognostic (1.27e-1)" "unprognostic (6.58e-2)" "unprognostic (2.45e-2)" "unprognostic (1.28e-1)" "unprognostic (2.34e-3)" "unprognostic (8.86e-2)" "unprognostic (4.92e-2)" "unprognostic (2.69e-1)" "unprognostic (4.94e-3)" "potential prognostic favorable (1.69e-5)" "unprognostic (2.41e-3)" "unprognostic (2.30e-1)" "unprognostic (2.70e-1)" "unprognostic (7.52e-2)" "unprognostic (9.71e-2)" "unprognostic (2.52e-1)" "unprognostic (8.19e-2)" "unprognostic (3.68e-1)" "unprognostic (1.49e-1)" "unprognostic (1.06e-2)" "unprognostic (2.77e-2)" "unprognostic (9.03e-2)" "unprognostic (2.78e-1)" "unprognostic (6.83e-2)" "unprognostic (1.41e-1)" "unprognostic (1.77e-1)" "unprognostic (5.81e-2)" "unprognostic (3.21e-1)" "unprognostic (1.80e-1)" "unprognostic (2.31e-1)" PRKAR1B ENSG00000188191 "Protein kinase cAMP-dependent type I regulatory subunit beta" P31321 7 549197-727650 "Disease related genes, Predicted intracellular proteins" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 10 "brain: 319.6" "Cell type enhanced" "Detected in many" "Late spermatids: 228.3;Oocytes: 386.8;Other brain neurons: 151.8;Platelets: 803.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026719 Approved NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 1: Neurons - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 47: Platelets - Hemostasis" 83 "HPA026719: " "unprognostic (3.46e-1)" "unprognostic (9.30e-2)" "unprognostic (1.90e-2)" "potential prognostic unfavorable (7.06e-4)" "unprognostic (1.74e-1)" "unprognostic (1.16e-1)" "unprognostic (4.06e-3)" "unprognostic (2.22e-1)" "unprognostic (1.55e-3)" "unprognostic (1.48e-1)" "unprognostic (9.99e-3)" "unprognostic (1.17e-1)" "unprognostic (5.20e-3)" "unprognostic (3.19e-2)" "unprognostic (3.19e-3)" "potential prognostic unfavorable (5.13e-4)" "unprognostic (2.38e-2)" "unprognostic (4.92e-2)" "unprognostic (2.63e-1)" "unprognostic (4.33e-3)" "unprognostic (3.38e-1)" "unprognostic (2.17e-2)" "unprognostic (5.61e-2)" "unprognostic (2.08e-1)" "unprognostic (1.59e-2)" "unprognostic (4.15e-2)" "unprognostic (2.82e-1)" "unprognostic (4.77e-2)" "unprognostic (2.06e-1)" "unprognostic (1.94e-1)" "unprognostic (1.16e-1)" PRKAR2A PRKAR2 ENSG00000114302 "Protein kinase cAMP-dependent type II regulatory subunit alpha" P13861 3 48744597-48847874 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 81.8;testis: 78.3" "Group enriched" "Detected in all" 4 "Early spermatids: 1048.8;Late spermatids: 1852.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005023, HPA038268" Uncertain Uncertain "Vesicles,Centriolar satellite,Basal body,Cytosol,Mid piece" NA NA 72000 "Cluster 35: Neutrophils - Protein binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 71 "Centriolar satellite, Basal body, Mid piece" "Vesicles, Cytosol" "CAB005023: , HPA038268: " "unprognostic (5.18e-3)" "unprognostic (5.25e-2)" "unprognostic (5.95e-2)" "unprognostic (4.17e-3)" "unprognostic (4.49e-3)" "unprognostic (1.07e-1)" "unprognostic (2.31e-1)" "unprognostic (1.66e-2)" "unprognostic (2.76e-2)" "potential prognostic unfavorable (2.54e-4)" "potential prognostic favorable (1.40e-5)" "unprognostic (6.56e-3)" "unprognostic (1.57e-1)" "potential prognostic unfavorable (1.12e-4)" "unprognostic (1.57e-1)" "unprognostic (3.43e-2)" "unprognostic (9.37e-2)" "unprognostic (1.34e-1)" "unprognostic (1.98e-1)" "unprognostic (2.44e-1)" "unprognostic (1.16e-2)" "unprognostic (8.07e-2)" "unprognostic (1.71e-1)" "unprognostic (1.36e-1)" "unprognostic (9.13e-3)" "unprognostic (1.82e-1)" "unprognostic (1.81e-1)" "unprognostic (1.68e-1)" "unprognostic (3.94e-1)" "unprognostic (1.29e-2)" "unprognostic (1.76e-1)" PRKAR2B PRKAR2 ENSG00000005249 "Protein kinase cAMP-dependent type II regulatory subunit beta" P31323 7 107044705-107161811 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 159.6" "Cell type enhanced" "Detected in many" "Adipocytes: 708.3;Erythrocyte progenitors: 303.9;Granulosa cells: 329.3;Megakaryocyte progenitors: 380.1;Megakaryocyte-Erythroid progenitors: 371.8;Megakaryocytes: 1075.6;Platelets: 1661.4;Podocytes: 247.8;Sertoli cells: 267.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 11.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "lymphoma: 32.8" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatic stellate cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008421 Enhanced Approved "Golgi apparatus,Centrosome,Basal body,Cytosol" NA NA 160000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 33: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 47: Platelets - Hemostasis" 41 "Golgi apparatus, Centrosome, Basal body, Cytosol" "HPA008421: " "unprognostic (1.48e-2)" "unprognostic (2.30e-1)" "unprognostic (2.50e-1)" "unprognostic (6.40e-2)" "unprognostic (8.34e-2)" "unprognostic (1.84e-2)" "unprognostic (9.74e-3)" "unprognostic (1.45e-1)" "unprognostic (2.86e-1)" "unprognostic (2.15e-1)" "unprognostic (2.88e-3)" "unprognostic (4.21e-2)" "unprognostic (2.27e-1)" "unprognostic (3.02e-2)" "unprognostic (9.22e-2)" "unprognostic (3.13e-1)" "unprognostic (1.33e-1)" "unprognostic (6.32e-2)" "unprognostic (1.71e-2)" "potential prognostic favorable (4.04e-5)" "unprognostic (2.26e-3)" "unprognostic (3.03e-1)" "unprognostic (7.24e-2)" "unprognostic (4.66e-2)" "unprognostic (2.22e-1)" "unprognostic (1.04e-1)" "unprognostic (3.93e-2)" "unprognostic (1.52e-1)" PRKCA "PKCA, PKCalpha" ENSG00000154229 "Protein kinase C alpha" P17252 17 66302613-66810743 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Angiogenesis, Apoptosis, Cell adhesion" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.9" "Cell type enhanced" "Detected in all" "Adrenal cortex cells: 995.0;Astrocytes: 1157.1;Bergmann glia: 1773.9;Choroid plexus epithelial cells: 988.3;Oligodendrocyte progenitor cells: 1180.8;Renal connecting tubule cells: 967.4;Retinal bipolar cells: 1304.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003844, HPA006563, HPA006564, CAB016290" Enhanced Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA 170000 "Cluster 11: T-cells - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 29: Forebrain - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 121 Cytosol "Vesicles, Plasma membrane" "CAB003844: , CAB016290: , HPA006563: , HPA006564: " "unprognostic (2.13e-2)" "unprognostic (5.59e-1)" "unprognostic (3.81e-2)" "potential prognostic unfavorable (3.97e-4)" "unprognostic (1.32e-1)" "unprognostic (7.67e-2)" "unprognostic (1.26e-1)" "unprognostic (3.98e-1)" "unprognostic (1.31e-2)" "unprognostic (2.33e-1)" "unprognostic (1.76e-1)" "unprognostic (1.99e-2)" "unprognostic (1.80e-1)" "unprognostic (5.83e-2)" "potential prognostic unfavorable (5.02e-4)" "unprognostic (3.50e-3)" "unprognostic (7.80e-2)" "unprognostic (3.38e-2)" "unprognostic (3.81e-2)" "unprognostic (8.91e-2)" "unprognostic (4.01e-1)" "unprognostic (1.77e-1)" "unprognostic (6.46e-3)" "unprognostic (7.15e-2)" "unprognostic (9.55e-2)" "unprognostic (2.61e-1)" "unprognostic (3.73e-2)" "unprognostic (2.50e-1)" "unprognostic (3.18e-1)" "unprognostic (4.68e-3)" "unprognostic (6.96e-3)" PRKCB "PKCB, PKCbeta, PRKCB1, PRKCB2" ENSG00000166501 "Protein kinase C beta" P05771 16 23835983-24220611 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins, Transporters" "Adaptive immunity, Apoptosis, Immunity, Transcription, Transcription regulation" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 104.6;lymphoid tissue: 44.0" "Cell type enhanced" "Detected in many" "B-cells: 1418.0;Brain inhibitory neurons: 679.4;Kupffer cells: 1054.6;monocytes: 812.4;Neutrophil progenitors: 1343.3;Neutrophils: 4257.1;pDCs: 805.3;Platelets: 762.8;Retinal amacrine cells: 740.9;Retinal bipolar cells: 614.3;Sertoli cells: 660.0;Thymocytes: 890.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Bone cancer: 46.8;Leukemia: 59.7;lymphoma: 24.6" "Adrenal gland - Macrophages, Liver - Kupffer cells, Skin - Keratinocyte (other), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003843, HPA048321, HPA054203" Approved Supported Nucleoplasm,Cytosol NA NA 390000 "Cluster 32: Basophils - Transcription" "Cluster 78: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 24: Neutrophils - Innate immunity signal integration" 31 Nucleoplasm Cytosol "CAB003843: , HPA048321: , HPA054203: " "unprognostic (1.06e-1)" "unprognostic (3.41e-3)" "unprognostic (3.37e-3)" "unprognostic (8.39e-3)" "unprognostic (1.76e-2)" "unprognostic (2.05e-1)" "unprognostic (1.15e-1)" "unprognostic (3.66e-2)" "unprognostic (5.24e-3)" "unprognostic (9.06e-3)" "unprognostic (7.61e-2)" "unprognostic (2.17e-1)" "unprognostic (6.78e-3)" "potential prognostic favorable (4.40e-5)" "unprognostic (1.71e-1)" "unprognostic (1.79e-1)" "unprognostic (3.37e-1)" "unprognostic (8.20e-2)" "unprognostic (1.01e-1)" "unprognostic (2.24e-2)" "unprognostic (6.18e-2)" "unprognostic (5.35e-2)" "unprognostic (4.85e-2)" "unprognostic (9.51e-3)" "unprognostic (2.32e-2)" "unprognostic (3.76e-2)" "unprognostic (1.25e-1)" "unprognostic (4.91e-1)" PRKCD ENSG00000163932 "Protein kinase C delta" Q05655 3 53156009-53192717 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 140.1;Neutrophils: 357.2;Platelets: 142.6" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 122.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 7 "dendritic cells: 55.3;granulocytes: 49.5;monocytes: 71.9" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Spleen - Neutrophils_2, Stomach - Gastric mucous cells" "Group enriched" "Detected in all" 5 "basal ganglia: 121.5;thalamus: 334.8" "Low region specificity" "Detected in all" "HPA001863, HPA001890, CAB010469, CAB013225" Enhanced Enhanced "Endoplasmic reticulum,Golgi apparatus,Vesicles,Cytosol" NA NA 30000 "Cluster 29: Non-specific - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 51: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 47 Cytosol "Endoplasmic reticulum, Golgi apparatus, Vesicles" "CAB010469: , CAB013225: , HPA001863: , HPA001890: " "unprognostic (3.23e-2)" "unprognostic (1.37e-1)" "unprognostic (2.55e-1)" "unprognostic (1.01e-2)" "unprognostic (8.54e-2)" "unprognostic (9.81e-2)" "unprognostic (1.18e-1)" "unprognostic (3.53e-2)" "unprognostic (2.99e-1)" "unprognostic (6.74e-2)" "potential prognostic favorable (8.14e-6)" "unprognostic (6.06e-2)" "unprognostic (8.02e-2)" "unprognostic (1.58e-3)" "unprognostic (3.82e-3)" "potential prognostic favorable (1.27e-4)" "unprognostic (1.60e-1)" "unprognostic (2.78e-2)" "unprognostic (1.18e-1)" "unprognostic (1.52e-1)" "unprognostic (1.00e-1)" "unprognostic (4.38e-2)" "unprognostic (2.38e-2)" "unprognostic (2.19e-1)" "unprognostic (7.55e-3)" "unprognostic (1.39e-1)" "unprognostic (2.74e-2)" "unprognostic (1.22e-1)" "unprognostic (3.20e-2)" "unprognostic (6.17e-2)" "unprognostic (1.41e-1)" PRKCE ENSG00000171132 "Protein kinase C epsilon" Q02156 2 45651345-46187990 "Cancer-related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Cell adhesion, Cell cycle, Cell division, Immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 28.9" "Cell type enhanced" "Detected in many" "Late spermatids: 932.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Lung - Endothelial cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001948, HPA008236, HPA044496" Enhanced Supported Supported "Vesicles,Plasma membrane,Intermediate filaments,Cytosol" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 27: Cerebellum - Synaptic function" "Cluster 51: Neurons - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 35: Neurons - Synaptic function & neurogenesis" 30 "Intermediate filaments, Cytosol" "Vesicles, Plasma membrane" "CAB001948: , HPA008236: , HPA044496: " "unprognostic (4.97e-2)" "unprognostic (8.67e-2)" "unprognostic (7.77e-2)" "unprognostic (8.60e-2)" "unprognostic (7.20e-2)" "unprognostic (1.93e-1)" "unprognostic (6.74e-2)" "unprognostic (2.76e-3)" "unprognostic (1.84e-1)" "unprognostic (1.91e-1)" "potential prognostic favorable (1.41e-10)" "unprognostic (5.19e-2)" "unprognostic (6.57e-2)" "unprognostic (1.65e-1)" "unprognostic (7.12e-2)" "unprognostic (1.49e-3)" "unprognostic (2.04e-1)" "unprognostic (2.23e-1)" "unprognostic (2.72e-2)" "unprognostic (1.14e-1)" "unprognostic (1.73e-2)" "unprognostic (3.44e-2)" "unprognostic (2.90e-2)" "unprognostic (9.64e-2)" "potential prognostic unfavorable (8.47e-4)" "unprognostic (1.20e-2)" "unprognostic (2.28e-2)" "unprognostic (9.93e-2)" "unprognostic (1.63e-1)" "unprognostic (1.09e-2)" "unprognostic (8.86e-2)" PRKCG "MGC57564, PKCC, PKCG, PKCgamma, SCA14" ENSG00000126583 "Protein kinase C gamma" P05129 19 53879190-53907652 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, RAS pathway related proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, FDA approved drug targets, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 26 "brain: 50.1" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 46.3;Brain inhibitory neurons: 48.8;Breast myoepithelial cells: 71.5;Breast secretory cells: 39.3;Endometrial glandular cells: 37.8;Endometrial luminal cells: 59.2;Endometrial stromal cells: 74.0;Oocytes: 36.8;pDCs: 44.4;Salivary basal cells: 52.0;Salivary myoepithelial cells: 145.0" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 3.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Pancreas - Alpha cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054560 Enhanced NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" 11 "HPA054560: " "unprognostic (9.96e-2)" "unprognostic (6.00e-2)" "unprognostic (1.83e-1)" "unprognostic (2.43e-1)" "unprognostic (7.02e-2)" "unprognostic (9.83e-3)" "unprognostic (3.69e-2)" "unprognostic (3.68e-1)" "unprognostic (1.72e-1)" "unprognostic (3.88e-2)" "unprognostic (1.01e-1)" "unprognostic (4.42e-1)" PRKCH "PKC-L, PKCL, PRKCL" ENSG00000027075 "Protein kinase C eta" P24723 14 61187559-61550976 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Differentiation "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 396.1;Hematopoietic stem cells: 491.5;Innate lymphoid cells: 435.9;Lymphatic endothelial cells: 394.8;NK-cells: 1248.0;T-cells: 971.6;Vascular endothelial cells: 612.9" "Group enriched" "Detected in all" 6 "endothelial cell: 1433.4;leukocyte: 1439.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "gdT-cell: 116.2;MAIT T-cell: 91.4;memory CD4 T-cell: 88.5;memory CD8 T-cell: 136.2;naive CD4 T-cell: 107.8;naive CD8 T-cell: 104.9;NK-cell: 113.1;T-reg: 80.4" "Group enriched" "Detected in all" 13 "NK-cells: 113.1;T-cells: 136.2" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells, Thyroid gland - Endothelial cells" "Group enriched" "Detected in all" 6 "basal ganglia: 28.0;thalamus: 17.9" "Low region specificity" "Detected in all" "HPA026294, HPA053709" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 27: T-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 38: Sub-cortical - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" Cytosol "Plasma membrane" "HPA026294: , HPA053709: " "unprognostic (6.50e-2)" "unprognostic (4.26e-2)" "unprognostic (7.46e-2)" "unprognostic (9.39e-2)" "unprognostic (1.13e-1)" "unprognostic (2.75e-1)" "unprognostic (1.26e-1)" "unprognostic (4.00e-1)" "unprognostic (3.38e-3)" "unprognostic (9.30e-2)" "potential prognostic favorable (1.11e-6)" "unprognostic (1.71e-3)" "unprognostic (1.56e-1)" "unprognostic (2.38e-2)" "unprognostic (3.82e-3)" "unprognostic (9.72e-3)" "unprognostic (6.76e-3)" "unprognostic (1.85e-1)" "unprognostic (6.24e-2)" "unprognostic (2.52e-1)" "unprognostic (3.51e-1)" "unprognostic (1.32e-1)" "unprognostic (6.13e-3)" "unprognostic (8.13e-2)" "unprognostic (1.23e-1)" "unprognostic (2.71e-2)" "unprognostic (2.06e-1)" "unprognostic (5.27e-3)" "unprognostic (6.96e-2)" "unprognostic (1.55e-1)" "unprognostic (1.04e-1)" PRKCI "DXS1179E, PKCI" ENSG00000163558 "Protein kinase C iota" P41743 3 170222424-170305977 "Cancer-related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Podocytes: 382.8;Prostatic club cells: 360.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Breast myoepithelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026574, HPA038635" Approved Supported "Microtubules,Cytokinetic bridge,Primary cilium,Cytosol" Yes No "Cluster 3: Non-specific - Nuclear processes" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 51: Secretory epithelial cells - Mixed function" 67 Cytosol "Microtubules, Cytokinetic bridge, Primary cilium" "HPA026574: , HPA038635: " "unprognostic (1.48e-1)" "unprognostic (1.87e-1)" "unprognostic (1.36e-1)" "unprognostic (7.05e-2)" "unprognostic (9.27e-2)" "unprognostic (1.32e-2)" "unprognostic (2.10e-1)" "unprognostic (4.84e-2)" "unprognostic (3.61e-1)" "unprognostic (1.91e-2)" "potential prognostic favorable (3.65e-7)" "unprognostic (3.78e-2)" "unprognostic (1.91e-1)" "unprognostic (1.08e-2)" "unprognostic (1.57e-2)" "unprognostic (6.15e-2)" "unprognostic (2.64e-1)" "unprognostic (6.97e-2)" "unprognostic (1.82e-2)" "unprognostic (2.06e-1)" "potential prognostic unfavorable (7.92e-4)" "potential prognostic unfavorable (2.05e-4)" "unprognostic (1.65e-1)" "unprognostic (3.97e-2)" "unprognostic (1.02e-2)" "unprognostic (1.25e-2)" "unprognostic (1.97e-1)" "unprognostic (4.50e-2)" "unprognostic (2.43e-1)" "unprognostic (3.45e-2)" "unprognostic (2.46e-1)" PRKCQ ENSG00000065675 "Protein kinase C theta" Q04759 10 6427143-6580301 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Immunity, Inflammatory response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "lymphoid tissue: 30.8;skeletal muscle: 115.2;tongue: 104.8" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 212.3;Distal convoluted tubule cells: 118.8;Hematopoietic stem cells: 144.1;Loop of henle epithelial cells: 164.3;Megakaryocyte progenitors: 177.3;Megakaryocyte-Erythroid progenitors: 163.6;Myonuclei: 413.3;NK-cells: 275.2;Oligodendrocytes: 107.4;Retinal pigment epithelial cells: 217.4;T-cells: 317.4;Thymic myoid cells: 104.7;Thymocytes: 154.1" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 245.3;leukocyte: 413.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "gdT-cell: 23.1;MAIT T-cell: 17.9;memory CD4 T-cell: 24.5;memory CD8 T-cell: 24.4;naive CD4 T-cell: 19.1;naive CD8 T-cell: 17.9;NK-cell: 13.3;T-reg: 39.8" "Group enriched" "Detected in many" 11 "NK-cells: 13.3;T-cells: 39.8" "Cancer enriched" "Detected in many" 6 "Leukemia: 18.2" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Liver - T-cells, Prostate - T-cells, Skeletal muscle - Skeletal myocytes, Skin - T-cells, Spleen - T-cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065279, HPA073098" Enhanced "Centriolar satellite" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 11: White matter - Signal transduction" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" 21 "Centriolar satellite" "HPA065279: , HPA073098: " "unprognostic (4.19e-2)" "unprognostic (6.06e-3)" "potential prognostic favorable (8.48e-4)" "unprognostic (7.96e-3)" "unprognostic (1.64e-1)" "unprognostic (1.35e-1)" "unprognostic (2.10e-1)" "unprognostic (1.03e-3)" "unprognostic (2.41e-1)" "unprognostic (5.04e-2)" "unprognostic (1.45e-3)" "unprognostic (8.22e-2)" "unprognostic (6.05e-2)" "unprognostic (2.61e-2)" "unprognostic (3.66e-2)" "unprognostic (1.11e-1)" "unprognostic (6.21e-3)" "unprognostic (3.33e-1)" "unprognostic (1.35e-1)" "unprognostic (9.12e-2)" "unprognostic (1.14e-2)" "unprognostic (8.72e-2)" "unprognostic (1.12e-3)" "unprognostic (7.92e-2)" "unprognostic (7.01e-2)" "unprognostic (1.05e-3)" "unprognostic (1.73e-2)" PRKCSH "G19P1, GIIB, PCLD, PLD1, VASAP-60" ENSG00000130175 "Protein kinase C substrate 80K-H" P14314 19 11435284-11450968 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 261.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004465, HPA041940, HPA043560" Supported Approved "Endoplasmic reticulum" "Intracellular and membrane" "No annotated function" NA NA 37000000 "Cluster 29: Non-specific - Unknown function" "Cluster 54: Non-specific - Ribosome" "Cluster 30: White matter - Myelination" "Cluster 23: Non-specific - Transcription" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 33 "Endoplasmic reticulum" "CAB004465: , HPA041940: , HPA043560: " "unprognostic (2.68e-1)" "unprognostic (3.66e-2)" "unprognostic (1.73e-1)" "unprognostic (9.42e-3)" "unprognostic (3.68e-1)" "unprognostic (1.08e-1)" "unprognostic (7.08e-2)" "unprognostic (2.82e-3)" "unprognostic (7.79e-2)" "unprognostic (6.74e-3)" "unprognostic (7.10e-2)" "unprognostic (3.22e-2)" "unprognostic (6.28e-2)" "unprognostic (4.46e-2)" "potential prognostic unfavorable (2.39e-4)" "unprognostic (2.05e-3)" "unprognostic (1.86e-3)" "unprognostic (5.53e-2)" "unprognostic (2.14e-2)" "unprognostic (1.65e-2)" "unprognostic (3.06e-1)" "unprognostic (3.56e-2)" "unprognostic (1.44e-1)" "unprognostic (1.70e-1)" "unprognostic (2.54e-3)" "unprognostic (1.86e-1)" "unprognostic (2.46e-1)" "unprognostic (1.97e-2)" "unprognostic (1.58e-1)" "unprognostic (7.33e-2)" "unprognostic (1.18e-1)" PRKCZ PKC2 ENSG00000067606 "Protein kinase C zeta" Q05513 1 2050411-2185395 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Inflammatory response" "Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 137.3" "Group enriched" "Detected in many" 4 "Alveolar cells type 1: 483.6;Late spermatids: 1336.6;Syncytiotrophoblasts: 1824.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "eosinophil: 16.3" "Lineage enriched" "Detected in many" 6 "granulocytes: 16.3" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Prostate - Prostate glandular cells, Skin - Keratinocyte (other), Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021851 Enhanced Supported "Plasma membrane,Basal body,Cytosol,Flagellar centriole,Mid piece,End piece" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 27: Cerebellum - Synaptic function" "Cluster 37: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 105 Cytosol "Plasma membrane, Basal body, Flagellar centriole, Mid piece, End piece" "HPA021851: " "unprognostic (9.52e-2)" "unprognostic (1.90e-1)" "unprognostic (2.91e-1)" "unprognostic (6.19e-2)" "unprognostic (1.79e-2)" "unprognostic (9.42e-3)" "unprognostic (2.00e-1)" "potential prognostic favorable (3.35e-4)" "unprognostic (3.07e-1)" "unprognostic (8.30e-3)" "potential prognostic favorable (2.71e-10)" "unprognostic (6.89e-3)" "unprognostic (1.19e-2)" "unprognostic (2.72e-2)" "potential prognostic unfavorable (6.15e-4)" "unprognostic (7.94e-3)" "unprognostic (1.31e-1)" "unprognostic (1.30e-2)" "unprognostic (1.42e-1)" "unprognostic (4.49e-2)" "unprognostic (1.11e-1)" "unprognostic (5.04e-2)" "unprognostic (6.53e-2)" "unprognostic (1.86e-1)" "unprognostic (8.70e-2)" "unprognostic (5.65e-2)" "unprognostic (1.82e-2)" "unprognostic (1.01e-2)" "unprognostic (1.77e-1)" "unprognostic (3.25e-1)" "unprognostic (8.46e-2)" PRKD1 "PKC-mu, PKCM, PKD, PRKCM" ENSG00000184304 "Protein kinase D1" Q15139 14 29576479-30191898 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Angiogenesis, Apoptosis, Differentiation, Immunity, Inflammatory response, Innate immunity, Neurogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 710.1;Ependymal cells: 619.6;Loop of henle epithelial cells: 765.5;Podocytes: 722.7;Prostatic glandular cells: 1753.5;Sertoli cells: 1511.7;Somatotrophs: 796.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 16.0" "Adipose visceral - Mesothelial cells, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018367, HPA029834" Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 21: Testis - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 30 "Plasma membrane" Cytosol "CAB018367: , HPA029834: " "unprognostic (1.35e-2)" "unprognostic (9.63e-2)" "unprognostic (1.91e-1)" "unprognostic (5.91e-2)" "unprognostic (1.20e-1)" "unprognostic (1.40e-2)" "unprognostic (8.79e-2)" "validated prognostic favorable (3.42e-8)" "validated prognostic favorable (2.18e-4)" "unprognostic (1.14e-1)" "unprognostic (6.67e-3)" "unprognostic (3.02e-1)" "unprognostic (3.32e-2)" "unprognostic (1.42e-1)" "unprognostic (2.86e-1)" "unprognostic (3.61e-2)" "unprognostic (2.03e-1)" "unprognostic (9.68e-2)" "unprognostic (3.10e-1)" "unprognostic (1.23e-2)" "unprognostic (3.78e-2)" "unprognostic (1.75e-2)" "unprognostic (7.71e-2)" "unprognostic (1.67e-3)" "unprognostic (1.67e-1)" "potential prognostic unfavorable (3.48e-4)" "unprognostic (2.94e-2)" PRKD2 "DKFZP586E0820, HSPC187, PKD2" ENSG00000105287 "Protein kinase D2" Q9BZL6 19 46674275-46717127 "Enzymes, Predicted intracellular proteins" "Adaptive immunity, Angiogenesis, Cell adhesion, Immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 196.7;Oocytes: 253.3" "Cell type enhanced" "Detected in all" "endothelial cell: 61.7;leukocyte: 61.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Colon - Endothelial cells, Liver - Vascular endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021490, HPA056727" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 29 Nucleoplasm Cytosol "HPA021490: , HPA056727: " "unprognostic (1.03e-1)" "unprognostic (2.12e-1)" "unprognostic (2.03e-2)" "unprognostic (5.18e-2)" "unprognostic (3.16e-1)" "unprognostic (1.05e-1)" "unprognostic (1.26e-1)" "unprognostic (4.71e-2)" "unprognostic (1.71e-1)" "unprognostic (1.62e-1)" "potential prognostic favorable (5.46e-5)" "unprognostic (1.30e-2)" "unprognostic (6.82e-2)" "unprognostic (2.75e-2)" "unprognostic (1.51e-2)" "unprognostic (8.19e-2)" "unprognostic (9.74e-3)" "unprognostic (1.11e-1)" "unprognostic (3.12e-1)" "unprognostic (8.93e-3)" "unprognostic (1.89e-2)" "unprognostic (1.55e-1)" "unprognostic (2.10e-1)" "unprognostic (8.62e-2)" "unprognostic (4.15e-1)" "unprognostic (2.01e-1)" "unprognostic (5.28e-2)" "unprognostic (1.66e-1)" "unprognostic (3.51e-1)" "unprognostic (6.21e-3)" "unprognostic (1.52e-1)" PRKD3 "EPK2, PRKCN" ENSG00000115825 "Protein kinase D3" O94806 2 37250502-37324833 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Melanocytes: 342.2;Rod photoreceptor cells: 285.2;Somatotrophs: 250.3" "Cell type enhanced" "Detected in all" "endothelial cell: 225.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Fibroblasts, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029529 Uncertain Supported "Nucleoplasm,Vesicles,Plasma membrane,Basal body,Cytosol" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 44: Non-specific - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 61: Schwann cells & Melanocytes - Mixed function" 4 "Plasma membrane, Cytosol" "Nucleoplasm, Vesicles, Basal body" "HPA029529: " "unprognostic (1.68e-2)" "unprognostic (1.45e-1)" "unprognostic (1.50e-2)" "potential prognostic unfavorable (7.12e-4)" "unprognostic (7.31e-2)" "unprognostic (1.72e-2)" "unprognostic (6.10e-2)" "unprognostic (1.31e-1)" "unprognostic (6.72e-2)" "potential prognostic unfavorable (4.50e-6)" "unprognostic (1.10e-3)" "unprognostic (1.89e-1)" "unprognostic (1.40e-1)" "unprognostic (3.51e-3)" "unprognostic (3.91e-2)" "unprognostic (4.11e-2)" "unprognostic (1.94e-2)" "unprognostic (2.12e-1)" "unprognostic (2.93e-1)" "unprognostic (4.10e-1)" "unprognostic (4.13e-2)" "unprognostic (2.05e-1)" "unprognostic (1.20e-1)" "unprognostic (1.19e-1)" "unprognostic (4.57e-2)" "unprognostic (8.80e-2)" "unprognostic (1.00e-1)" "unprognostic (4.52e-2)" "unprognostic (4.28e-1)" "unprognostic (4.89e-2)" "unprognostic (4.31e-2)" PRKDC "DNA-PKC, DNA-PKcs, DNAPK, DNAPKc, DNPK1, HYRC, HYRC1, p350, p460, XRCC7" ENSG00000253729 "Protein kinase, DNA-activated, catalytic subunit" P78527 8 47773111-47960178 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, DNA damage, DNA recombination, DNA repair, Immunity, Innate immunity, Ribosome biogenesis" "DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythrocyte progenitors: 779.7;Neutrophils: 1216.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005167, HPA035174" Supported Enhanced Nucleoplasm NA NA 860000 "Cluster 24: Non-specific - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 185 Nucleoplasm "CAB005167: , HPA035174: " "unprognostic (6.38e-2)" "unprognostic (3.76e-2)" "unprognostic (1.66e-1)" "unprognostic (5.82e-3)" "unprognostic (7.04e-2)" "unprognostic (1.63e-2)" "unprognostic (4.05e-1)" "unprognostic (2.90e-2)" "unprognostic (2.86e-1)" "unprognostic (2.50e-3)" "potential prognostic favorable (3.76e-4)" "unprognostic (3.49e-1)" "unprognostic (4.34e-2)" "potential prognostic unfavorable (1.20e-4)" "unprognostic (4.86e-3)" "potential prognostic unfavorable (6.38e-5)" "unprognostic (1.77e-2)" "unprognostic (8.02e-2)" "unprognostic (1.97e-2)" "unprognostic (3.69e-2)" "unprognostic (9.98e-2)" "potential prognostic unfavorable (5.55e-4)" "unprognostic (5.60e-1)" "unprognostic (7.41e-2)" "unprognostic (4.80e-2)" "potential prognostic favorable (5.18e-4)" "unprognostic (2.84e-2)" "unprognostic (1.57e-1)" "unprognostic (2.77e-1)" "unprognostic (1.56e-2)" "unprognostic (1.80e-1)" PRKG1 "PGK, PKG, PKG1, PRKG1B, PRKGR1B" ENSG00000185532 "Protein kinase cGMP-dependent 1" Q13976 10 50990888-52298423 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Allosteric enzyme, Kinase, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 64.3" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 2299.3;Cardiomyocytes: 1895.3;Choroid plexus epithelial cells: 2812.5;Ependymal cells: 1729.0;Fibro-adipogenic progenitors: 1734.0;Myonuclei: 4254.4;Pericytes: 2669.2;Podocytes: 2490.4;Renal connecting tubule cells: 2013.0;Retinal ganglion cells: 2707.8;Vascular smooth muscle cells: 4014.6" "Cell type enhanced" "Detected in all" "pericyte: 4323.8;vascular associated smooth muscle cell: 7325.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 38 "basophil: 7.3" "Lineage enriched" "Detected in single" 50 "granulocytes: 7.3" "Cancer enhanced" "Detected in many" "Rhabdoid: 9.7" "Adipose subcutaneous - Smooth muscle cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Minor Salivary Gland - Fibroblasts, Pituitary gland - Fibroblasts, Spleen - Fibroblasts_1, Spleen - Fibroblasts_2, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007699, CAB009629" Enhanced Approved Vesicles,Cytosol NA NA 36000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 110: Mural cells - ECM organization" 11 "Vesicles, Cytosol" "CAB009629: , HPA007699: " "unprognostic (9.85e-2)" "unprognostic (2.14e-2)" "unprognostic (1.39e-2)" "unprognostic (8.37e-3)" "unprognostic (4.09e-2)" "unprognostic (1.84e-3)" "unprognostic (9.54e-2)" "unprognostic (1.70e-1)" "unprognostic (2.24e-1)" "unprognostic (1.70e-2)" "validated prognostic favorable (3.89e-4)" "validated prognostic favorable (6.99e-4)" "unprognostic (3.11e-1)" "unprognostic (1.39e-1)" "unprognostic (1.94e-1)" "unprognostic (3.29e-2)" "unprognostic (3.04e-1)" "unprognostic (4.46e-3)" "unprognostic (2.60e-1)" "unprognostic (2.70e-1)" "unprognostic (3.06e-1)" "unprognostic (2.03e-2)" "unprognostic (1.37e-1)" "unprognostic (3.47e-3)" "unprognostic (1.10e-1)" "unprognostic (6.91e-2)" PRKG2 "cGKII, PKG2, PRKGR2" ENSG00000138669 "Protein kinase cGMP-dependent 2" Q13237 4 81087370-81215222 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 12.9;prostate: 9.3" "Cell type enhanced" "Detected in many" "Enterocytes: 96.4;Hematopoietic stem cells: 524.5;Megakaryocyte-Erythroid progenitors: 83.3;Melanocytes: 48.8;Oligodendrocyte progenitor cells: 182.8;Prostatic glandular cells: 104.2;Thyrotrophs: 71.7" "Cell type enhanced" "Detected in many" "oligodendrocyte precursor cell: 215.9" "Cancer enhanced" "Detected in some" "Skin Cutaneous Melanoma (TCGA): 7.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Alveolar cells type 1, Pituitary gland - Lactotropes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA007386, CAB018739" Approved NA NA "Cluster 41: Basophils - Unknown function" "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 49: Hindbrain - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 2 "CAB018739: , HPA007386: " "unprognostic (3.20e-1)" "unprognostic (1.03e-2)" "unprognostic (2.67e-1)" "unprognostic (1.14e-2)" "unprognostic (1.09e-1)" "unprognostic (1.16e-2)" "potential prognostic unfavorable (2.91e-4)" "unprognostic (1.21e-1)" "unprognostic (2.71e-2)" PRKN "AR-JP, PARK2, parkin, PDJ" ENSG00000185345 "Parkin RBR E3 ubiquitin protein ligase" O60260 6 161347417-162727775 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Autophagy, Transcription, Transcription regulation, Ubl conjugation pathway" Transferase "Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 26.6;tongue: 14.8" "Cell type enhanced" "Detected in many" "Bergmann glia: 1152.0;Cardiomyocytes: 1330.4;Myonuclei: 1513.7;Renal collecting duct intercalated cells: 1171.7;Sertoli cells: 1217.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 10.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in some" 9 "Rhabdoid: 14.3" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB016257, HPA036012" Enhanced Supported "Nuclear speckles,Cytosol" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 33: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 55: Myocytes - Oxidative muscle function" 1427 "Nuclear speckles" Cytosol "CAB016257: , HPA036012: " "unprognostic (1.83e-1)" "unprognostic (4.24e-2)" "unprognostic (1.73e-1)" "unprognostic (2.08e-1)" "unprognostic (1.35e-1)" "unprognostic (6.08e-2)" "potential prognostic favorable (4.21e-7)" "unprognostic (5.92e-3)" "potential prognostic favorable (6.88e-7)" "unprognostic (1.81e-1)" "unprognostic (4.39e-1)" "unprognostic (2.14e-1)" "unprognostic (7.62e-3)" "unprognostic (2.13e-1)" "unprognostic (3.61e-1)" "unprognostic (7.79e-3)" "unprognostic (3.14e-2)" "unprognostic (3.16e-1)" PRKRA "DYT16, HSD14, PACT, RAX" ENSG00000180228 "Protein activator of interferon induced protein kinase EIF2AK2" O75569 2 178431292-178451512 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction, RNA-mediated gene silencing" RNA-binding "Disease variant, Dystonia, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 456.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004648, HPA034996, HPA034997" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 248 Cytosol Nucleoplasm "CAB004648: , HPA034996: , HPA034997: " "unprognostic (1.19e-1)" "unprognostic (3.15e-2)" "unprognostic (2.01e-1)" "unprognostic (2.03e-1)" "unprognostic (1.11e-2)" "unprognostic (2.57e-1)" "unprognostic (3.57e-2)" "unprognostic (5.48e-2)" "unprognostic (9.02e-2)" "unprognostic (5.77e-3)" "potential prognostic favorable (1.29e-6)" "unprognostic (3.81e-2)" "unprognostic (7.47e-2)" "potential prognostic unfavorable (1.03e-6)" "unprognostic (1.66e-2)" "unprognostic (9.59e-3)" "unprognostic (1.20e-1)" "unprognostic (9.56e-2)" "unprognostic (1.60e-1)" "unprognostic (1.06e-2)" "unprognostic (2.89e-1)" "unprognostic (5.34e-3)" "unprognostic (1.64e-2)" "unprognostic (1.84e-1)" "unprognostic (3.73e-1)" "unprognostic (5.64e-2)" "unprognostic (1.33e-1)" "unprognostic (8.54e-2)" "unprognostic (8.89e-2)" "unprognostic (3.58e-1)" "unprognostic (4.41e-1)" PRKRIP1 "C114, FLJ13902, KRBOX3" ENSG00000128563 "PRKR interacting protein 1" Q9H875 7 102363872-102426676 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Myonuclei: 294.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051146 Uncertain Supported "Actin filaments,Cytosol" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 54: Non-specific - Ribosome" "Cluster 15: Non-specific - Transcription" "Cluster 39: Non-specific - Transcription" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 4 "Actin filaments" Cytosol "HPA051146: " "unprognostic (5.09e-2)" "unprognostic (8.04e-2)" "unprognostic (3.54e-1)" "unprognostic (1.67e-1)" "unprognostic (1.03e-3)" "unprognostic (3.91e-2)" "unprognostic (9.52e-3)" "unprognostic (5.46e-2)" "unprognostic (1.34e-2)" "unprognostic (2.38e-3)" "unprognostic (3.98e-3)" "unprognostic (1.22e-1)" "unprognostic (1.91e-2)" "unprognostic (1.18e-2)" "unprognostic (3.99e-2)" "unprognostic (1.70e-1)" "unprognostic (3.35e-2)" "unprognostic (1.03e-2)" "unprognostic (6.37e-2)" "unprognostic (8.12e-3)" "unprognostic (9.15e-2)" "unprognostic (7.69e-3)" "potential prognostic unfavorable (1.76e-4)" "unprognostic (2.98e-2)" "unprognostic (4.90e-2)" "unprognostic (1.30e-1)" "unprognostic (6.71e-2)" "unprognostic (2.09e-1)" "unprognostic (4.28e-2)" "unprognostic (1.49e-1)" "unprognostic (2.46e-2)" PRKX PKX1 ENSG00000183943 "Protein kinase cAMP-dependent X-linked catalytic subunit" P51817 X 3604340-3713649 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Angiogenesis, Differentiation" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 31.6" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 290.4;Endometrial glandular cells: 423.0;Endometrial luminal cells: 365.6;Innate lymphoid cells: 208.0;Loop of henle epithelial cells: 309.5;Mast cells: 658.3;NK-cells: 337.5" "Cell type enhanced" "Detected in all" "leukocyte: 109.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 11.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015324 Supported Supported Nucleoplasm No No "Cluster 32: Basophils - Transcription" "Cluster 72: Kidney - Transmembrane transport" "Cluster 44: Non-specific - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 58: Mast cells - Allergic inflammatory responses" 27 Nucleoplasm "HPA015324: " "unprognostic (4.36e-2)" "unprognostic (2.42e-1)" "unprognostic (6.32e-2)" "unprognostic (1.52e-1)" "unprognostic (2.45e-2)" "unprognostic (4.81e-2)" "unprognostic (1.23e-1)" "unprognostic (3.23e-3)" "unprognostic (1.54e-1)" "unprognostic (2.81e-1)" "potential prognostic favorable (2.50e-5)" "unprognostic (1.21e-3)" "unprognostic (8.18e-2)" "unprognostic (2.36e-1)" "unprognostic (9.80e-2)" "unprognostic (6.87e-2)" "unprognostic (2.61e-1)" "unprognostic (2.52e-2)" "potential prognostic favorable (8.81e-4)" "unprognostic (4.10e-1)" "unprognostic (1.49e-1)" "unprognostic (2.17e-1)" "unprognostic (2.29e-1)" "unprognostic (1.12e-1)" "unprognostic (5.23e-2)" "unprognostic (1.10e-1)" "unprognostic (2.68e-1)" "unprognostic (2.26e-2)" "unprognostic (1.38e-1)" "unprognostic (2.08e-1)" "unprognostic (2.15e-1)" PRL ENSG00000172179 Prolactin P01236 6 22287244-22302826 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" Lactation Hormone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1701 "pituitary gland: 58560.7" "Cell type enriched" "Detected in some" 20 "Lactotrophs: 22782.4" "Cell type enriched" "Detected in single" 24 "midbrain-derived inhibitory: 14.9" "Cancer enhanced" "Detected in some" "Bladder Urothelial Carcinoma (TCGA): 2.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "Leukemia: 10.8;lymphoma: 9.9;ovarian cancer: 6.5" "Pituitary gland - Lactotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB023353, HPA042416, HPA062017" Enhanced "Secreted to blood" Hormone NA NA 53900000 2300000 "Cluster 20: Pituitary gland - Hormone signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 1 "CAB023353: , HPA042416: , HPA062017: " "unprognostic (4.60e-3)" "unprognostic (2.51e-1)" PRLH PRH ENSG00000071677 "Prolactin releasing hormone" P81277 2 237566574-237567175 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.7;heart muscle: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Breast Invasive Carcinoma (TCGA): 1.0;Uterine Corpus Endometrial Carcinoma (TCGA): 1.4" "Region enhanced" "Detected in many" "medulla oblongata: 47.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "breast cancer: 1.0" "Group enriched" "Detected in some" 58 "hypothalamus: 11.3;pons and medulla: 21.5" "Region enriched" "Detected in single" 14 "medulla oblongata: 1.5" HPA014976 Uncertain "Secreted in brain" Hormone NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 43: Hindbrain - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 107: Ciliated cells - Cilia assembly & function" "HPA014976: " "unprognostic (1.45e-3)" "unprognostic (7.79e-1)" PRLHR "GPR10, PrRPR" ENSG00000119973 "Prolactin releasing hormone receptor" P49683 10 118589997-118595648 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 4.9;endometrium 1: 4.6;pituitary gland: 6.3;smooth muscle: 3.2" "Group enriched" "Detected in some" 4 "Adrenal medulla cells: 31.9;Gonadotrophs: 48.1" "Cell type enhanced" "Detected in some" "astrocyte: 7.9;CGE interneuron: 19.6;MGE interneuron: 11.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 1.5;prostate cancer: 1.4" "Adrenal gland - Adrenal medulla cells" "Region enhanced" "Detected in single" "hypothalamus: 1.7" "Low region specificity" "Detected in all" HPA039361 Enhanced NA NA "Cluster 75: Ovary - Mixed function" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 109: Neurons - Neuronal signaling" 1 "HPA039361: " "unprognostic (1.63e-2)" PRLR ENSG00000113494 "Prolactin receptor" P16471 5 35048756-35230487 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 120.7;parathyroid gland: 77.7;placenta: 47.2" "Cell type enriched" "Detected in many" 8 "Choroid plexus epithelial cells: 3804.9" "Cell type enriched" "Detected in many" 17 "choroid plexus epithelial cell: 2839.2" "Group enriched" "Detected in many" 6 "Breast Invasive Carcinoma (TCGA): 40.8;Kidney Chromophobe (TCGA): 16.4" "Region enriched" "Detected in all" 19 "choroid plexus: 1734.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 8 "breast cancer: 36.0" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Breast - Breast glandular cells, Kidney - Proximal tubular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Intracellular and membrane" Receptor NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 8 "unprognostic (8.08e-3)" "unprognostic (3.52e-1)" "unprognostic (2.35e-2)" "unprognostic (1.50e-1)" "unprognostic (1.34e-1)" "unprognostic (3.42e-2)" "unprognostic (3.44e-3)" "unprognostic (1.35e-3)" "unprognostic (1.74e-2)" "unprognostic (1.47e-1)" "unprognostic (8.39e-2)" "unprognostic (3.30e-3)" "unprognostic (1.04e-3)" "unprognostic (2.65e-1)" "unprognostic (9.50e-2)" "unprognostic (2.22e-1)" "potential prognostic favorable (7.01e-4)" "unprognostic (8.49e-2)" "unprognostic (6.88e-3)" "unprognostic (2.51e-2)" "unprognostic (7.77e-2)" "unprognostic (9.49e-2)" "unprognostic (3.13e-1)" PRM1 CT94.1 ENSG00000175646 "Protamine 1" P04553 16 11280841-11281330 "Predicted intracellular proteins" "Differentiation, DNA condensation, Spermatogenesis" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1247 "testis: 15140.1" "Cell type enriched" "Detected in some" 7 "Late spermatids: 1088815.8" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 93 "Testicular Germ Cell Tumor (TCGA): 21.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "HPA055150, HPA059371" Enhanced Enhanced Nucleoplasm,Cytosol NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 1 "Nucleoplasm, Cytosol" "HPA055150: , HPA059371: " "unprognostic (8.04e-2)" PRM2 CT94.2 ENSG00000122304 "Protamine 2" P04554 16 11275639-11276480 "Predicted intracellular proteins" "Differentiation, DNA condensation, Spermatogenesis" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1223 "testis: 11179.1" "Cell type enriched" "Detected in some" 11 "Late spermatids: 867689.8" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 85 "Testicular Germ Cell Tumor (TCGA): 26.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "CAB032738, HPA056386" Enhanced NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 34: Testis cancer - Unknown function" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 3 "CAB032738: , HPA056386: " "unprognostic (1.08e-1)" PRM3 ENSG00000178257 "Protamine 3" Q9NNZ6 16 11273199-11273629 "Predicted intracellular proteins" "Differentiation, DNA condensation, Spermatogenesis" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 32 "testis: 80.6" "Cell type enriched" "Detected in some" 5 "Late spermatids: 5420.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 2: Neurons - Nucleosome" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" PRMT1 "ANM1, HCP1, HRMT1L2" ENSG00000126457 "Protein arginine methyltransferase 1" Q99873 19 49675786-49689029 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 279.4;Migrating cytotrophoblasts: 284.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022550, HPA069769, HPA072136" Supported Supported Nucleoplasm NA NA 16000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 24: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 197 Nucleoplasm "CAB022550: , HPA069769: , HPA072136: " "unprognostic (9.39e-2)" "unprognostic (1.25e-1)" "unprognostic (4.88e-2)" "unprognostic (7.96e-2)" "unprognostic (1.13e-3)" "unprognostic (3.69e-1)" "unprognostic (4.36e-2)" "unprognostic (8.91e-2)" "unprognostic (1.54e-2)" "unprognostic (1.85e-2)" "unprognostic (2.56e-2)" "unprognostic (7.10e-2)" "unprognostic (2.72e-1)" "validated prognostic unfavorable (9.68e-7)" "validated prognostic unfavorable (1.90e-4)" "unprognostic (3.60e-3)" "unprognostic (8.06e-2)" "unprognostic (1.27e-1)" "unprognostic (1.45e-1)" "unprognostic (1.27e-1)" "unprognostic (9.07e-2)" "unprognostic (2.74e-1)" "unprognostic (1.49e-1)" "unprognostic (3.15e-2)" "unprognostic (1.92e-2)" "unprognostic (4.87e-2)" "unprognostic (2.18e-1)" "unprognostic (1.72e-1)" "unprognostic (1.12e-1)" "unprognostic (1.16e-1)" "unprognostic (1.34e-1)" PRMT2 "HRMT1L1, MGC111373" ENSG00000160310 "Protein arginine methyltransferase 2" P55345 21 46635595-46665124 "Enzymes, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018976, HPA029591" Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 69: Skin cancer - ECM organization" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 22 "Nucleoplasm, Cytosol" "HPA018976: , HPA029591: " "unprognostic (1.19e-1)" "unprognostic (4.62e-3)" "unprognostic (1.91e-1)" "unprognostic (9.94e-3)" "unprognostic (5.49e-2)" "unprognostic (2.53e-1)" "unprognostic (1.01e-1)" "unprognostic (4.38e-2)" "unprognostic (1.45e-1)" "unprognostic (3.26e-1)" "potential prognostic favorable (5.89e-4)" "unprognostic (1.32e-2)" "unprognostic (1.34e-2)" "potential prognostic unfavorable (3.64e-5)" "unprognostic (1.49e-1)" "unprognostic (8.98e-2)" "unprognostic (2.33e-2)" "unprognostic (4.27e-2)" "unprognostic (1.37e-1)" "unprognostic (7.78e-2)" "unprognostic (1.56e-1)" "unprognostic (4.82e-3)" "unprognostic (1.88e-1)" "unprognostic (9.03e-2)" "unprognostic (1.50e-1)" "unprognostic (1.62e-1)" "unprognostic (1.70e-2)" "unprognostic (6.75e-3)" "unprognostic (5.44e-2)" "unprognostic (2.03e-2)" "unprognostic (3.21e-1)" PRMT3 HRMT1L3 ENSG00000185238 "Protein arginine methyltransferase 3" O60678 11 20387558-20509338 "Enzymes, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007832, CAB022083" Uncertain NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 19 "CAB022083: , HPA007832: " "unprognostic (1.98e-2)" "unprognostic (5.36e-2)" "unprognostic (3.60e-1)" "unprognostic (1.40e-1)" "unprognostic (1.56e-1)" "unprognostic (5.85e-2)" "unprognostic (3.15e-2)" "unprognostic (8.69e-2)" "unprognostic (1.13e-1)" "unprognostic (1.71e-3)" "potential prognostic favorable (2.91e-4)" "unprognostic (6.60e-2)" "unprognostic (1.20e-1)" "potential prognostic unfavorable (8.83e-5)" "unprognostic (2.31e-3)" "unprognostic (4.15e-2)" "unprognostic (2.79e-2)" "unprognostic (1.50e-1)" "unprognostic (3.19e-2)" "unprognostic (1.73e-1)" "unprognostic (9.15e-3)" "potential prognostic unfavorable (1.39e-5)" "unprognostic (6.61e-2)" "unprognostic (2.27e-1)" "unprognostic (2.83e-3)" "unprognostic (7.51e-3)" "unprognostic (8.98e-2)" "unprognostic (1.92e-1)" "unprognostic (2.90e-1)" "unprognostic (3.73e-2)" "unprognostic (1.10e-1)" PRMT5 "HRMT1L5, SKB1, SKB1Hs" ENSG00000100462 "Protein arginine methyltransferase 5" O14744 14 22920525-22929408 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 103.3;Oocytes: 115.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005525, CAB012459, HPA064708" Approved Supported Nucleoplasm,Cytosol NA NA 51000 "Cluster 13: Non-specific - Mitochondria" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 84: Apical squamous epithelium - Cornification" 162 "Nucleoplasm, Cytosol" "CAB012459: , HPA005525: , HPA064708: " "unprognostic (1.26e-1)" "unprognostic (2.03e-1)" "unprognostic (9.57e-2)" "unprognostic (3.23e-3)" "unprognostic (1.58e-2)" "unprognostic (1.90e-1)" "unprognostic (4.35e-3)" "unprognostic (3.40e-3)" "unprognostic (2.80e-3)" "unprognostic (1.72e-3)" "potential prognostic favorable (7.93e-6)" "unprognostic (7.70e-3)" "unprognostic (4.82e-2)" "validated prognostic unfavorable (1.21e-5)" "validated prognostic unfavorable (5.60e-4)" "unprognostic (4.72e-3)" "unprognostic (4.18e-3)" "unprognostic (5.70e-3)" "unprognostic (7.57e-3)" "unprognostic (7.07e-2)" "unprognostic (4.17e-2)" "potential prognostic unfavorable (7.28e-4)" "unprognostic (4.70e-2)" "unprognostic (1.82e-1)" "unprognostic (6.98e-2)" "unprognostic (6.41e-2)" "unprognostic (1.62e-1)" "unprognostic (3.93e-1)" "unprognostic (2.14e-1)" "unprognostic (6.74e-2)" "unprognostic (1.83e-2)" PRMT6 "FLJ10559, HRMT1L6" ENSG00000198890 "Protein arginine methyltransferase 6" Q96LA8 1 107056674-107067636 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059424 Approved Supported Nucleoplasm,Nucleoli NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 61: Non-specific - Transcription" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 37: Non-specific - mRNA processing" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" 84 "Nucleoplasm, Nucleoli" "HPA059424: " "unprognostic (5.64e-2)" "unprognostic (1.02e-2)" "unprognostic (4.10e-3)" "unprognostic (1.96e-1)" "unprognostic (9.99e-2)" "unprognostic (2.71e-2)" "unprognostic (1.28e-1)" "unprognostic (3.08e-1)" "unprognostic (3.19e-1)" "unprognostic (1.03e-2)" "potential prognostic favorable (1.06e-4)" "unprognostic (1.98e-2)" "unprognostic (1.81e-2)" "validated prognostic unfavorable (4.80e-5)" "validated prognostic unfavorable (8.09e-4)" "unprognostic (7.75e-3)" "unprognostic (9.04e-3)" "unprognostic (1.19e-1)" "unprognostic (8.80e-3)" "unprognostic (6.52e-2)" "unprognostic (3.47e-1)" "unprognostic (2.96e-1)" "unprognostic (4.39e-1)" "unprognostic (3.00e-1)" "unprognostic (3.31e-3)" "unprognostic (1.90e-1)" "unprognostic (1.06e-1)" "unprognostic (7.10e-3)" "unprognostic (8.80e-2)" "unprognostic (4.96e-2)" "unprognostic (3.97e-2)" PRMT7 "FLJ10640, KIAA1933" ENSG00000132600 "Protein arginine methyltransferase 7" Q9NVM4 16 68310951-68360852 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Differentiation, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Transferase" "Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Epicardial cells: 279.7;Myonuclei: 108.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044241 Supported Enhanced "Nucleoplasm,Nucleoli fibrillar center" No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 9 Nucleoplasm "Nucleoli fibrillar center" "HPA044241: " "unprognostic (4.48e-3)" "unprognostic (3.86e-2)" "unprognostic (1.51e-1)" "unprognostic (1.27e-2)" "unprognostic (1.96e-2)" "unprognostic (2.16e-1)" "unprognostic (1.17e-1)" "potential prognostic favorable (3.57e-4)" "unprognostic (8.24e-3)" "unprognostic (4.49e-2)" "unprognostic (4.12e-3)" "unprognostic (8.68e-2)" "unprognostic (1.41e-2)" "unprognostic (5.55e-2)" "unprognostic (1.11e-1)" "unprognostic (4.74e-1)" "unprognostic (1.94e-1)" "unprognostic (9.66e-2)" "unprognostic (3.49e-2)" "unprognostic (2.41e-1)" "unprognostic (3.52e-2)" "unprognostic (3.17e-2)" "unprognostic (1.36e-2)" "unprognostic (5.04e-2)" "unprognostic (7.03e-3)" "potential prognostic unfavorable (1.09e-4)" "unprognostic (7.29e-2)" "unprognostic (1.26e-2)" "unprognostic (6.89e-2)" "unprognostic (2.26e-1)" "unprognostic (2.19e-2)" PRMT8 "HRMT1L3, HRMT1L4" ENSG00000111218 "Protein arginine methyltransferase 8" Q9NR22 12 3381349-3593973 "Enzymes, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 24.0" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 43.3;Brain inhibitory neurons: 102.0;Early primary spermatocytes: 38.1;Late primary spermatocytes: 32.6;Renal collecting duct intercalated cells: 35.9;Respiratory ciliated cells: 183.4;Respiratory deuterosomal cells: 29.0;Retinal amacrine cells: 72.5;Retinal bipolar cells: 67.2;Retinal ganglion cells: 30.9;Sertoli cells: 33.3;Transitional alveolar cells: 63.4" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 211.5;medium spiny neuron: 179.9" "Cancer enhanced" "Detected in some" "Kidney Chromophobe (TCGA): 2.2;Thyroid Carcinoma (TCGA): 4.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.6;thyroid cancer: 1.4" "Colon - Colon enteroendocrine cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039747, HPA069769" Enhanced NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Neurons - Synaptic function & neurogenesis" 17 "HPA039747: , HPA069769: " "unprognostic (2.55e-1)" "unprognostic (1.62e-2)" "unprognostic (1.30e-1)" "unprognostic (3.02e-1)" "unprognostic (3.61e-1)" "unprognostic (1.63e-1)" PRMT9 "FLJ46629, PRMT10" ENSG00000164169 "Protein arginine methyltransferase 9" Q6P2P2 4 147637785-147684163 "Enzymes, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 194.6;Innate lymphoid cells: 438.1;Lactotrophs: 208.6;Mast cells: 200.2;monocytes: 203.9;Ovarian stromal cells: 260.7;pDCs: 345.6;Somatotrophs: 249.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036844, HPA042537" Uncertain Approved Nucleoplasm,Microtubules,Cytosol NA NA "Cluster 32: Basophils - Transcription" "Cluster 75: Ovary - Mixed function" "Cluster 2: Neurons - Nucleosome" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 103: Non-specific - Basic cellular processes" 7 Microtubules "Nucleoplasm, Cytosol" "HPA036844: , HPA042537: " "unprognostic (2.40e-2)" "unprognostic (1.47e-1)" "unprognostic (2.85e-2)" "unprognostic (1.70e-1)" "unprognostic (4.41e-3)" "unprognostic (2.97e-3)" "unprognostic (1.13e-1)" "unprognostic (1.82e-2)" "potential prognostic unfavorable (6.23e-4)" "validated prognostic favorable (4.45e-10)" "validated prognostic favorable (1.28e-5)" "unprognostic (4.88e-3)" "unprognostic (8.05e-2)" "unprognostic (2.87e-1)" "unprognostic (1.71e-1)" "unprognostic (1.87e-1)" "unprognostic (1.98e-3)" "unprognostic (5.46e-2)" "unprognostic (3.46e-2)" "unprognostic (1.07e-2)" "unprognostic (1.25e-1)" "unprognostic (1.07e-3)" "unprognostic (1.39e-1)" "unprognostic (1.16e-1)" "unprognostic (2.20e-1)" "unprognostic (2.11e-1)" "unprognostic (1.42e-3)" "unprognostic (2.17e-2)" PRND "dJ1068H6.4, DOPPEL, DPL, PrPLP" ENSG00000171864 "Prion like protein doppel" Q9UKY0 20 4721909-4728460 "Predicted membrane proteins, Transporters" Fertilization Prion "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 16 "choroid plexus: 38.3;testis: 66.3" "Cell type enriched" "Detected in some" 15 "Sertoli cells: 99.8" "Cell type enriched" "Detected in some" 13 "choroid plexus epithelial cell: 27.2" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 4.6" "Region enriched" "Detected in many" 24 "choroid plexus: 67.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Rhabdoid: 4.9" "Testis - Sertoli cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA043373 Enhanced NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 4 "HPA043373: " "unprognostic (9.82e-2)" "unprognostic (6.54e-2)" "unprognostic (2.71e-3)" "unprognostic (1.73e-2)" "unprognostic (3.21e-2)" "unprognostic (1.71e-1)" "unprognostic (2.91e-2)" "unprognostic (3.22e-1)" PRNP "AltPrP, CD230, CJD, GSS, PRIP, PRP" ENSG00000171867 "Prion protein" P04156 20 4686350-4701590 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Cell cycle, Growth arrest" Prion "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 480.4" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 343.1;Epididymal basal cells: 383.5;Kupffer cells: 447.9;Ocular epithelial cells: 461.4;Retinal pigment epithelial cells: 379.4;Schwann cells: 369.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 9 "basophil: 879.6" "Lineage enriched" "Detected in all" 9 "granulocytes: 879.6" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Breast - Breast myoepithelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042754, HPA043398" Enhanced Approved "Nuclear membrane,Vesicles,Cytosol" NA Yes 4300000 "Cluster 41: Basophils - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 100: Stratified epithelial cells - Barrier functions" 320 "Nuclear membrane, Cytosol" Vesicles "HPA042754: , HPA043398: " "unprognostic (6.95e-2)" "unprognostic (5.10e-2)" "unprognostic (2.02e-1)" "unprognostic (1.38e-1)" "unprognostic (9.13e-2)" "unprognostic (2.45e-2)" "unprognostic (3.49e-3)" "unprognostic (2.00e-3)" "unprognostic (5.66e-3)" "unprognostic (4.30e-2)" "potential prognostic favorable (3.02e-4)" "unprognostic (1.87e-1)" "unprognostic (2.44e-1)" "potential prognostic unfavorable (4.78e-6)" "unprognostic (1.11e-3)" "unprognostic (1.30e-1)" "unprognostic (6.04e-2)" "unprognostic (1.84e-2)" "potential prognostic unfavorable (2.81e-4)" "unprognostic (5.09e-2)" "unprognostic (5.76e-2)" "unprognostic (1.74e-1)" "unprognostic (1.53e-1)" "unprognostic (1.54e-1)" "unprognostic (2.50e-2)" "unprognostic (1.11e-2)" "unprognostic (2.99e-1)" "unprognostic (1.20e-2)" "unprognostic (3.68e-1)" "unprognostic (2.81e-1)" "unprognostic (2.37e-2)" PROB1 C5orf65 ENSG00000228672 "Proline rich basic protein 1" E7EW31 5 139390592-139395104 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 24.7;skeletal muscle: 75.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 6.5;Ependymal cells: 23.9;Epididymal efferent duct absorptive cells: 5.8;Epididymal efferent duct ciliated cells: 6.7;Hepatic stellate cells: 6.5;Myonuclei: 10.1;Myosatellite cells: 6.3;Syncytiotrophoblasts: 5.0;Thymic myoid cells: 27.2" "Cell type enriched" "Detected in some" 7 "ependymal cell: 39.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA053354, HPA060103" Enhanced Enhanced Nucleoplasm NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 46: Brainstem - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 34: Ciliated cells - Cilia assembly & function" Nucleoplasm "HPA053354: , HPA060103: " "unprognostic (4.02e-1)" "unprognostic (2.09e-2)" "unprognostic (2.83e-2)" "unprognostic (7.11e-2)" "unprognostic (4.91e-2)" "unprognostic (1.46e-1)" "unprognostic (6.52e-2)" "unprognostic (1.61e-2)" "unprognostic (7.31e-3)" "unprognostic (2.86e-2)" "unprognostic (1.96e-3)" "unprognostic (3.75e-2)" "unprognostic (3.04e-2)" "unprognostic (1.24e-2)" "unprognostic (2.86e-3)" "unprognostic (9.69e-2)" "unprognostic (5.44e-3)" "unprognostic (2.52e-2)" "unprognostic (7.39e-2)" "unprognostic (3.04e-1)" "unprognostic (2.14e-1)" "unprognostic (5.92e-2)" "unprognostic (7.76e-2)" PROC ENSG00000115718 "Protein C, inactivator of coagulation factors Va and VIIIa" P04070 2 127418427-127429242 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 41 "liver: 584.1" "Cell type enriched" "Detected in some" 9 "Hepatocytes: 519.6" "Cell type enhanced" "Detected in some" "deep-layer near-projecting: 3.9;lower rhombic lip: 6.0" "Cancer enriched" "Detected in many" 7 "Liver Hepatocellular Carcinoma (TCGA): 301.0" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 9 "plasmacytoid DC: 59.8" "Lineage enriched" "Detected in many" 9 "dendritic cells: 59.8" "Cancer enriched" "Detected in many" 6 "liver cancer: 28.4" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Outer root sheath cells" "Not detected" "Not detected" "HPA005550, CAB016721, CAB016792" Approved "Secreted to blood" "Blood coagulation" NA NA 1400000000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 2 "CAB016721: , CAB016792: , HPA005550: " "unprognostic (7.94e-3)" "unprognostic (2.01e-2)" "unprognostic (3.70e-1)" "unprognostic (1.49e-3)" "unprognostic (1.09e-1)" "unprognostic (7.90e-2)" "unprognostic (3.68e-1)" "unprognostic (1.67e-2)" "unprognostic (4.80e-3)" "unprognostic (1.54e-2)" "unprognostic (4.75e-3)" "unprognostic (7.99e-3)" "potential prognostic favorable (9.35e-4)" "unprognostic (4.14e-1)" "unprognostic (1.95e-2)" "unprognostic (5.99e-2)" "unprognostic (3.90e-1)" "unprognostic (4.17e-2)" "unprognostic (1.51e-2)" "unprognostic (1.29e-1)" "unprognostic (6.63e-2)" "unprognostic (2.81e-2)" "unprognostic (4.92e-2)" "unprognostic (3.76e-3)" "unprognostic (3.37e-1)" "unprognostic (1.73e-2)" "unprognostic (9.58e-3)" PROCA1 MGC39650 ENSG00000167525 "Protein interacting with cyclin A1" Q8NCQ7 17 28703197-28711888 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 21 "testis: 122.2" "Cell type enriched" "Detected in many" 6 "Late spermatids: 12075.9" "Cell type enhanced" "Detected in many" "Bergmann glia: 14.8;ependymal cell: 15.3" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 10.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA023648, HPA030218" Approved Approved "Nuclear membrane,Golgi apparatus" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 79: Testis - Spermatogenesis" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 35: RS4;11 - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 1 "Nuclear membrane" "Golgi apparatus" "HPA023648: , HPA030218: " "unprognostic (1.24e-1)" "unprognostic (2.47e-2)" "unprognostic (9.68e-2)" "unprognostic (2.82e-3)" "unprognostic (1.14e-2)" "unprognostic (1.28e-1)" "unprognostic (2.23e-2)" "unprognostic (9.31e-2)" "potential prognostic favorable (1.25e-4)" "unprognostic (2.37e-3)" "unprognostic (1.73e-1)" "unprognostic (2.46e-1)" "unprognostic (4.34e-2)" "unprognostic (6.35e-3)" "unprognostic (1.16e-1)" "unprognostic (6.59e-2)" "unprognostic (6.33e-2)" "unprognostic (2.31e-1)" "unprognostic (1.87e-1)" PROCR "CCD41, CD201, EPCR" ENSG00000101000 "Protein C receptor" Q9UNN8 20 35172072-35216240 "Candidate cardiovascular disease genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Blood coagulation, Hemostasis" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 120.1" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 134.3;Extravillous trophoblasts: 183.2;Fibro-adipogenic progenitors: 264.5;Fibroblasts: 139.4;Granulosa cells: 177.6;Lymphatic endothelial cells: 199.7;Mesothelial cells: 396.9;Pericytes: 120.1" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 51.7;endothelial cell: 66.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 14.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Endothelial cells, Stomach - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA039461 Enhanced NA NA 85000000 "Cluster 33: Non-specific - ATP binding" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 6: Non-specific - Immune response" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 108: Fibroblasts - ECM organization" 2 "HPA039461: " "unprognostic (2.04e-1)" "unprognostic (3.22e-1)" "unprognostic (3.21e-1)" "unprognostic (1.30e-2)" "unprognostic (4.55e-2)" "unprognostic (1.64e-1)" "unprognostic (1.63e-1)" "unprognostic (1.87e-3)" "unprognostic (6.11e-2)" "unprognostic (1.79e-2)" "unprognostic (2.74e-2)" "unprognostic (1.68e-3)" "unprognostic (8.57e-3)" "unprognostic (1.14e-1)" "unprognostic (7.52e-2)" "unprognostic (2.54e-2)" "unprognostic (8.08e-3)" "unprognostic (1.85e-1)" "unprognostic (1.11e-1)" "unprognostic (4.43e-2)" "unprognostic (6.13e-2)" "unprognostic (1.57e-1)" "unprognostic (2.26e-1)" "unprognostic (1.62e-1)" "unprognostic (5.74e-2)" "unprognostic (3.85e-2)" "unprognostic (8.42e-2)" "unprognostic (4.53e-3)" "unprognostic (7.66e-2)" "unprognostic (3.37e-1)" "unprognostic (1.73e-2)" PRODH "HSPOX2, PIG6, PRODH1, PRODH2, TP53I6" ENSG00000100033 "Proline dehydrogenase 1" O43272 22 18912777-18936553 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Proline metabolism" Oxidoreductase "Disease variant, Schizophrenia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 59.8;choroid plexus: 63.6;skeletal muscle: 46.7" "Group enriched" "Detected in some" 4 "Astrocytes: 12.8;Bergmann glia: 10.4;Choroid plexus epithelial cells: 11.5;Enterocytes: 5.9;Melanocytes: 4.5;Respiratory basal cells: 7.1" "Group enriched" "Detected in some" 5 "astrocyte: 13.8;Bergmann glia: 8.7;choroid plexus epithelial cell: 9.4" "Cancer enriched" "Detected in many" 4 "Testicular Germ Cell Tumor (TCGA): 31.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 9.2" "Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes" HPA020361 Approved Approved Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 27: Breast cancer - Unknown function" "Cluster 28: Astrocytes - Homeostasis & neuron support" Mitochondria "Nucleoplasm, Vesicles" "HPA020361: " "unprognostic (3.64e-1)" "unprognostic (1.83e-2)" "unprognostic (2.76e-1)" "unprognostic (1.21e-3)" "unprognostic (2.14e-1)" "unprognostic (7.53e-2)" "unprognostic (1.36e-3)" "unprognostic (1.03e-1)" "unprognostic (4.84e-3)" "potential prognostic favorable (1.20e-4)" "unprognostic (1.95e-1)" "unprognostic (8.52e-2)" "unprognostic (8.52e-3)" "unprognostic (2.23e-1)" "unprognostic (1.78e-1)" "unprognostic (1.93e-1)" "unprognostic (1.50e-1)" "unprognostic (1.04e-1)" "unprognostic (1.18e-2)" "unprognostic (1.36e-1)" "unprognostic (5.98e-2)" "unprognostic (5.92e-2)" "unprognostic (2.13e-1)" "unprognostic (2.67e-2)" PRODH "HSPOX2, PIG6, PRODH1, PRODH2, TP53I6" ENSG00000277196 "Proline dehydrogenase 1" Unmapped 138082-161852 "Human disease related genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 14 "choroid plexus: 449.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 13.1;Endometrial ciliated cells: 3.8;Enterocytes: 8.9;Respiratory basal cells: 6.8;Respiratory deuterosomal cells: 3.1;Respiratory secretory cells: 3.2;Retinal pigment epithelial cells: 4.3;Thymic myoid cells: 9.5" "Region enriched" "Detected in all" 5 "choroid plexus: 350.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 37.0" HPA020361 Uncertain Approved Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" Mitochondria "Nucleoplasm, Vesicles" "HPA020361: " PRODH2 HSPOX1 ENSG00000250799 "Proline dehydrogenase 2" Q9UF12 19 35799988-35813299 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Proline metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 35 "kidney: 154.3;liver: 187.9" "Group enriched" "Detected in some" 4 "Hepatocytes: 191.4;Proximal tubule cells: 326.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Kidney Renal Clear Cell Carcinoma (TCGA): 18.8;Liver Hepatocellular Carcinoma (TCGA): 64.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "liver cancer: 9.1" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA051287 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 16: Liver & Kidney - Metabolism" "Cluster 18: Liver cancer - Metabolism" "Cluster 88: Proximal tubular cells - Transmembrane transport" Nucleoplasm Cytosol "HPA051287: " "unprognostic (1.15e-2)" "unprognostic (1.41e-2)" "unprognostic (1.67e-1)" "unprognostic (2.34e-1)" "unprognostic (4.01e-2)" PROK1 "EGVEGF, PK1, PRK1" ENSG00000143125 "Prokineticin 1" P58294 1 110451149-110457358 "Predicted secreted proteins" Angiogenesis "Growth factor, Mitogen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 190.8;placenta: 47.2;testis: 56.2" "Cell type enhanced" "Detected in some" "Granulosa cells: 160.6;Leydig cells: 193.6;Ovarian stromal cells: 82.0;Peritubular myoid cells: 620.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Prostate Adenocarcinoma (TCGA): 4.7;Testicular Germ Cell Tumor (TCGA): 7.7" "Region enhanced" "Detected in many" "medulla oblongata: 10.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 1.3;Rhabdoid: 1.2" "Colon - Colon enteroendocrine cells" "Region enriched" "Detected in single" 11 "pons and medulla: 1.4" "Low region specificity" "Detected in many" "Secreted to blood" "Growth factor" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 43: Hindbrain - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 94: Gonadal somatic cells - Mixed function" "unprognostic (1.75e-1)" "unprognostic (1.67e-2)" "unprognostic (4.72e-2)" "unprognostic (3.40e-3)" "unprognostic (7.33e-2)" "unprognostic (1.03e-1)" "unprognostic (5.49e-2)" "potential prognostic favorable (8.92e-4)" "unprognostic (1.86e-1)" PROK2 "BV8, KAL4, MIT1, PK2" ENSG00000163421 "Prokineticin 2" Q9HC23 3 71771655-71785206 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Biological rhythms" Neuropeptide "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 60.9;lymphoid tissue: 20.1" "Cell type enriched" "Detected in some" 13 "Neutrophils: 1546.6" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 3.2;ependymal cell: 7.4;medium spiny neuron: 3.2" "Cancer enhanced" "Detected in some" "Ovary Serous Cystadenocarcinoma (TCGA): 3.2" "Region enriched" "Detected in many" 7 "cerebral cortex: 30.8" "Immune cell enriched" "Detected in many" 50 "neutrophil: 416.1" "Lineage enriched" "Detected in many" 50 "granulocytes: 416.1" "Cancer enhanced" "Detected in some" "Leukemia: 8.0;Myeloma: 5.7" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Skeletal muscle - Neutrophils, Spleen - Neutrophils_2, Stomach - Neutrophils, Testis - Early spermatids, Thyroid gland - Neutrophils" "Group enriched" "Detected in some" 6 "basal ganglia: 2.7;hypothalamus: 1.1;olfactory bulb: 3.5" "Low region specificity" "Detected in many" HPA041408 Approved "Secreted to blood" Neuropeptide NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 15: Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 4 "HPA041408: " "unprognostic (2.41e-1)" "unprognostic (8.96e-2)" "unprognostic (2.04e-1)" "unprognostic (8.04e-2)" "unprognostic (7.19e-3)" "unprognostic (1.33e-1)" PROKR1 "GPR73, GPR73a, PKR1, ZAQ" ENSG00000169618 "Prokineticin receptor 1" Q8TCW9 2 68643579-68658251 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 1.5;adrenal gland: 1.0;epididymis: 3.3" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 10.6;Epididymal principal cells: 1.9;Late spermatids: 3.0;Pituitary stem cells: 2.9" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Bone cancer: 3.4;Neuroblastoma: 1.2" "Adrenal gland - Adrenal medulla cells, Breast - Endothelial cells, Colon - Colon enteroendocrine cells" "Region enhanced" "Detected in many" "spinal cord: 9.0" HPA029396 Uncertain NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 43: Hindbrain - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" 13 "HPA029396: " "unprognostic (8.90e-2)" PROKR2 "dJ680N4.3, GPR73b, GPR73L1, GPRg2, KAL3, PKR2" ENSG00000101292 "Prokineticin receptor 2" Q8NFJ6 20 5299218-5316954 "Disease related genes, G-protein coupled receptors, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.5" "Group enriched" "Detected in some" 6 "Cardiomyocytes: 37.8;Salivary duct cells: 15.2" "Cell type enhanced" "Detected in some" "deep-layer corticothalamic and 6b: 2.1;deep-layer intratelencephalic: 1.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 1.2" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Pituitary gland - Somatotropes, Testis - Early spermatids" "Region enhanced" "Detected in many" "olfactory bulb: 17.0" "Low region specificity" "Detected in all" HPA047281 Uncertain NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 5 "HPA047281: " "unprognostic (2.27e-2)" PROM1 "AC133, CD133, CORD12, MCDR2, PROML1, RP41, STGD4" ENSG00000007062 "Prominin 1" O43490 4 15963076-16084378 "CD markers, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cone-rod dystrophy, Disease variant, Retinitis pigmentosa, Stargardt disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "retina: 252.8" "Group enriched" "Detected in many" 4 "Cone photoreceptor cells: 1157.2;Rod photoreceptor cells: 808.8" "Group enriched" "Detected in many" 4 "endothelial cell: 166.7;ependymal cell: 43.0;oligodendrocyte precursor cell: 58.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Uterine cancer: 32.2" "Adrenal gland - Adrenal medulla cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Skin - Eccrine sweat gland cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004922, CAB011525, HPA031053, CAB080375, CAB080376" Enhanced Approved "Plasma membrane" NA NA 51000 "Cluster 42: Retina - Visual perception" "Cluster 47: Endothelial cells - Vasculature" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 79: Photoreceptor cells - Phototransduction" 7 "Plasma membrane" "CAB011525: , CAB080375: , CAB080376: , HPA004922: , HPA031053: " "unprognostic (3.11e-2)" "unprognostic (9.79e-2)" "unprognostic (4.24e-1)" "unprognostic (1.56e-1)" "unprognostic (1.83e-1)" "unprognostic (1.39e-2)" "unprognostic (2.42e-1)" "unprognostic (9.17e-3)" "unprognostic (1.69e-1)" "unprognostic (5.66e-2)" "unprognostic (1.10e-2)" "unprognostic (3.42e-3)" "potential prognostic favorable (2.33e-5)" "unprognostic (1.10e-1)" "unprognostic (1.67e-1)" "unprognostic (4.40e-2)" "unprognostic (1.36e-1)" "unprognostic (2.62e-1)" "unprognostic (1.63e-1)" "unprognostic (1.32e-1)" "unprognostic (1.61e-1)" "unprognostic (2.14e-3)" "unprognostic (2.83e-2)" "unprognostic (3.33e-1)" "unprognostic (5.68e-2)" "unprognostic (1.44e-1)" "unprognostic (2.05e-1)" "unprognostic (1.32e-3)" "unprognostic (1.59e-1)" "unprognostic (9.12e-2)" "unprognostic (2.75e-1)" PROM2 ENSG00000155066 "Prominin 2" Q8N271 2 95274449-95291308 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 84.0" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 72.8;Esophageal apical cells: 201.4;Esophageal suprabasal cells: 136.8;Ocular epithelial cells: 88.2;Papillary tip epithelial cells: 86.6;Prostatic hillock cells: 106.4;Salivary duct cells: 178.8;Urothelial cells: 77.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 80.1;head and neck cancer: 80.5" "Breast - Breast glandular cells, Kidney - Ascending Loop of Henle cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in single" "Not detected" "Not detected" "CAB046005, HPA063728" Enhanced Approved "Nucleoplasm,Plasma membrane,Cell Junctions,Mid piece,Principal piece,End piece,Annulus" NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 37: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 2 "Nucleoplasm, Plasma membrane" "Cell Junctions, Mid piece, Principal piece, End piece, Annulus" "CAB046005: , HPA063728: " "unprognostic (1.31e-1)" "potential prognostic unfavorable (3.62e-4)" "unprognostic (1.13e-2)" "unprognostic (3.01e-1)" "unprognostic (3.96e-1)" "unprognostic (2.40e-2)" "unprognostic (2.24e-3)" "unprognostic (9.35e-2)" "unprognostic (2.04e-1)" "potential prognostic unfavorable (5.88e-6)" "unprognostic (4.51e-3)" "unprognostic (1.26e-2)" "unprognostic (3.13e-2)" "unprognostic (8.60e-3)" "unprognostic (1.63e-1)" "unprognostic (1.86e-2)" "unprognostic (6.53e-3)" "unprognostic (7.23e-2)" "unprognostic (1.84e-1)" "potential prognostic unfavorable (1.14e-4)" "unprognostic (2.13e-1)" "unprognostic (1.76e-1)" "unprognostic (4.99e-2)" "unprognostic (4.32e-3)" "unprognostic (2.70e-1)" "unprognostic (2.75e-2)" "unprognostic (2.54e-1)" "unprognostic (6.58e-2)" "unprognostic (7.34e-3)" PROP1 ENSG00000175325 "PROP paired-like homeobox 1" O75360 5 177992235-177996242 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" DNA-binding "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "pituitary gland: 1.1" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "CGE interneuron: 1.5;hippocampal dentate gyrus: 2.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA049839 Enhanced NA NA "Cluster 20: Pituitary gland - Hormone signaling" "Cluster 34: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" 42 "HPA049839: " PRORP "KIAA0391, MRPP3" ENSG00000100890 "Protein only RNase P catalytic subunit" O15091 14 35121846-35277622 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "Hydrolase, Nuclease" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Astrocytes: 60.9;Bergmann glia: 50.3;Brain excitatory neurons: 48.4;Brain inhibitory neurons: 50.4;Choroid plexus epithelial cells: 114.2;Ependymal cells: 62.1;Epicardial cells: 84.1;Microglia: 63.4;Oligodendrocyte progenitor cells: 61.9;Oligodendrocytes: 69.3;Other brain neurons: 48.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020459 Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 76: Non-specific - Metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 22: Non-specific - Basic cellular functions" 2 Mitochondria Nucleoplasm "HPA020459: " "unprognostic (1.13e-1)" "unprognostic (1.85e-1)" "unprognostic (3.36e-3)" "unprognostic (1.30e-2)" "unprognostic (2.02e-1)" "unprognostic (8.60e-2)" "unprognostic (1.60e-3)" "unprognostic (6.79e-2)" "unprognostic (4.12e-2)" "potential prognostic favorable (4.77e-10)" "unprognostic (1.48e-3)" "unprognostic (3.81e-3)" "unprognostic (8.13e-3)" "unprognostic (2.36e-2)" "unprognostic (1.87e-2)" "unprognostic (3.56e-1)" "unprognostic (8.02e-2)" "unprognostic (1.60e-2)" "unprognostic (1.31e-1)" "potential prognostic unfavorable (6.28e-4)" "unprognostic (4.37e-2)" "unprognostic (1.12e-1)" "unprognostic (2.16e-1)" "unprognostic (1.31e-1)" "unprognostic (5.78e-2)" "unprognostic (1.59e-1)" "unprognostic (3.71e-2)" "unprognostic (1.05e-1)" "unprognostic (4.28e-2)" PROS1 PROS ENSG00000184500 "Protein S" P07225 3 93873051-93980003 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis" "Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 133.4;liver: 264.9" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 1010.7;Ependymal cells: 305.1;Hepatocytes: 460.3;Platelets: 328.6;Respiratory ciliated cells: 174.7;Schwann cells: 194.9" "Group enriched" "Detected in all" 4 "choroid plexus epithelial cell: 939.1;ependymal cell: 337.2" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 34 "choroid plexus: 214.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 46.7" "Adrenal gland - Fibroblasts, Liver - Hepatocytes, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007724, HPA023974, CAB032610" Approved "Secreted to blood" "Blood coagulation" NA NA 22500000000 13000000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 36: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 19 "CAB032610: , HPA007724: , HPA023974: " "unprognostic (3.93e-2)" "unprognostic (1.13e-2)" "unprognostic (1.41e-1)" "potential prognostic unfavorable (1.88e-4)" "unprognostic (2.02e-2)" "unprognostic (6.63e-2)" "unprognostic (1.61e-1)" "unprognostic (1.24e-1)" "unprognostic (1.20e-1)" "unprognostic (3.82e-3)" "potential prognostic favorable (3.02e-7)" "unprognostic (5.17e-3)" "unprognostic (1.34e-1)" "unprognostic (7.58e-2)" "unprognostic (4.64e-1)" "unprognostic (6.34e-2)" "unprognostic (3.68e-1)" "unprognostic (6.29e-2)" "unprognostic (1.38e-1)" "unprognostic (2.91e-2)" "unprognostic (4.28e-3)" "unprognostic (1.04e-1)" "unprognostic (2.67e-1)" "unprognostic (1.24e-1)" "unprognostic (8.44e-2)" "unprognostic (6.81e-2)" "unprognostic (7.35e-2)" "potential prognostic unfavorable (1.52e-4)" "unprognostic (1.80e-1)" "unprognostic (7.22e-2)" "unprognostic (2.94e-1)" PROSER1 "bA50D16.2, C13orf23, FLJ12661" ENSG00000120685 "Proline and serine rich 1" Q86XN7 13 39009865-39038089 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034225, HPA055687" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 49: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 2 Nucleoplasm Cytosol "CAB034225: , HPA055687: " "unprognostic (2.24e-2)" "unprognostic (1.03e-2)" "unprognostic (6.21e-3)" "unprognostic (2.10e-1)" "unprognostic (1.49e-1)" "unprognostic (5.87e-3)" "unprognostic (8.79e-2)" "unprognostic (1.10e-1)" "unprognostic (6.44e-2)" "potential prognostic favorable (1.71e-4)" "unprognostic (1.27e-1)" "unprognostic (1.67e-1)" "unprognostic (3.65e-3)" "unprognostic (3.69e-1)" "unprognostic (4.62e-3)" "unprognostic (3.91e-2)" "unprognostic (4.05e-2)" "unprognostic (2.52e-2)" "unprognostic (1.31e-2)" "unprognostic (1.11e-1)" "unprognostic (4.13e-3)" "unprognostic (3.06e-1)" "unprognostic (3.68e-2)" "unprognostic (1.02e-1)" "unprognostic (1.40e-1)" "unprognostic (1.17e-1)" "unprognostic (2.86e-1)" "unprognostic (1.30e-1)" "unprognostic (1.23e-1)" PROSER2 "C10orf47, MGC35403" ENSG00000148426 "Proline and serine rich 2" Q86WR7 10 11823339-11872277 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 40.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 77.7;Endometrial glandular cells: 92.5;Endometrial luminal cells: 83.0;Hepatocytes: 95.6;Loop of henle epithelial cells: 102.6;Pancreatic duct cells: 77.3;Platelets: 77.6;Urothelial cells: 89.5" "Cell type enhanced" "Detected in many" "endothelial cell: 42.5;fibroblast: 29.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 19.3" HPA041337 Uncertain Uncertain "Plasma membrane,Cytosol" NA NA 66000 "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 51: Secretory epithelial cells - Mixed function" 8 "Plasma membrane, Cytosol" "HPA041337: " "unprognostic (2.92e-1)" "potential prognostic favorable (3.19e-4)" "unprognostic (6.75e-2)" "unprognostic (4.00e-2)" "unprognostic (7.01e-3)" "unprognostic (1.87e-3)" "unprognostic (1.74e-1)" "unprognostic (1.24e-3)" "unprognostic (7.08e-3)" "unprognostic (9.86e-2)" "unprognostic (9.16e-3)" "unprognostic (6.90e-3)" "unprognostic (4.46e-3)" "unprognostic (1.34e-1)" "potential prognostic favorable (4.93e-4)" "unprognostic (4.36e-1)" "unprognostic (2.23e-1)" "unprognostic (2.47e-2)" "potential prognostic unfavorable (8.30e-4)" "unprognostic (1.14e-1)" "unprognostic (3.64e-2)" "unprognostic (3.20e-2)" "unprognostic (7.36e-2)" "unprognostic (6.34e-2)" "unprognostic (1.64e-1)" "unprognostic (9.84e-2)" "unprognostic (1.07e-2)" PROSER3 "C19orf55, FLJ30657" ENSG00000167595 "Proline and serine rich 3" Q2NL68 19 35758143-35771166 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 40.3;Respiratory ciliated cells: 52.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 10.2" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Macrophages, Liver - Vascular endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058492 Approved Approved "Golgi apparatus" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 48: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 107: Ciliated cells - Cilia assembly & function" 6 "Golgi apparatus" "HPA058492: " "unprognostic (6.70e-2)" "unprognostic (6.11e-2)" "unprognostic (9.55e-2)" "unprognostic (1.59e-1)" "unprognostic (4.69e-2)" "unprognostic (5.17e-1)" "unprognostic (8.46e-2)" "unprognostic (1.63e-2)" "unprognostic (6.27e-2)" "unprognostic (7.27e-2)" "unprognostic (3.79e-2)" "unprognostic (1.27e-1)" "unprognostic (1.64e-1)" "unprognostic (2.70e-1)" "unprognostic (2.92e-2)" "unprognostic (7.65e-2)" "unprognostic (8.93e-2)" "unprognostic (5.42e-1)" "unprognostic (5.19e-2)" "unprognostic (5.82e-3)" "unprognostic (2.67e-1)" "unprognostic (9.51e-3)" "unprognostic (3.60e-1)" "unprognostic (6.96e-3)" "unprognostic (2.03e-1)" "unprognostic (1.52e-1)" "unprognostic (1.15e-2)" "unprognostic (1.38e-1)" PROX1 ENSG00000117707 "Prospero homeobox 1" Q92786 1 213983181-214041510 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 81.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 220.4;Corticotrophs: 213.2;Hepatocytes: 424.3;Lymphatic endothelial cells: 611.7;Myosatellite cells: 182.1;Pancreatic duct cells: 167.1;Respiratory ionocytes: 177.8;Retinal bipolar cells: 310.4;Retinal horizontal cells: 548.9;Tuft cells: 149.9" "Cell type enhanced" "Detected in many" "CGE interneuron: 244.6;hippocampal dentate gyrus: 215.1;oligodendrocyte: 156.7" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 21.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 15.3;Neuroblastoma: 24.5" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Cardiomyocytes, Kidney - Ascending Loop of Henle cells, Stomach - Gastric enteroendocrine cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000842, HPA001030, HPA027298" Enhanced Nucleoplasm,Cytosol No No "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 6 Nucleoplasm Cytosol "HPA000842: , HPA001030: , HPA027298: " "unprognostic (8.41e-2)" "unprognostic (2.95e-1)" "unprognostic (2.39e-2)" "unprognostic (2.31e-2)" "unprognostic (1.92e-2)" "unprognostic (2.10e-1)" "unprognostic (3.22e-1)" "unprognostic (3.13e-2)" "unprognostic (1.19e-2)" "unprognostic (9.53e-2)" "unprognostic (4.73e-1)" "unprognostic (2.54e-1)" "unprognostic (2.70e-1)" "unprognostic (2.88e-3)" "unprognostic (2.66e-3)" "unprognostic (5.18e-2)" "unprognostic (1.71e-1)" "unprognostic (2.47e-2)" "potential prognostic unfavorable (8.15e-4)" "unprognostic (8.82e-2)" PROX2 FLJ36749 ENSG00000119608 "Prospero homeobox 2" Q3B8N5 14 74852871-74876154 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "bone marrow: 2.3" "Cell type enhanced" "Detected in some" "Adipocytes: 5.1;Cardiomyocytes: 15.0;Epicardial cells: 6.8;Microglia: 9.6;NK-cells: 3.9;Retinal amacrine cells: 5.6;Thymocytes: 8.5" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 11.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "neutrophil: 10.7" "Lineage enriched" "Detected in many" 7 "granulocytes: 10.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA045057 Uncertain NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 40: Non-specific - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "HPA045057: " "unprognostic (5.32e-2)" "unprognostic (4.19e-3)" PROZ PZ ENSG00000126231 "Protein Z, vitamin K dependent plasma glycoprotein" P22891 13 113158648-113172386 "Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Serine protease homolog" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "liver: 109.2" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 83.0" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 11 "Liver Hepatocellular Carcinoma (TCGA): 16.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" HPA052006 Supported "Secreted to blood" "Blood coagulation" NA NA 1720000000 690000000 "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 5: Non-specific - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 1 "HPA052006: " "unprognostic (2.57e-1)" "unprognostic (5.05e-2)" "unprognostic (1.00e-3)" "unprognostic (3.44e-3)" "unprognostic (1.02e-1)" PRPF18 hPrp18 ENSG00000165630 "Pre-mRNA processing factor 18" Q99633 10 13586939-13668445 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037599, HPA047950" Supported Approved "Nuclear speckles,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 16: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 65 "Nuclear speckles" Cytosol "HPA037599: , HPA047950: " "unprognostic (3.52e-1)" "unprognostic (1.15e-3)" "unprognostic (3.61e-2)" "unprognostic (1.76e-2)" "unprognostic (1.10e-1)" "unprognostic (2.44e-1)" "unprognostic (1.71e-1)" "potential prognostic favorable (9.46e-6)" "unprognostic (2.13e-1)" "unprognostic (3.70e-2)" "potential prognostic favorable (3.54e-8)" "unprognostic (7.72e-3)" "unprognostic (3.16e-1)" "potential prognostic unfavorable (9.16e-8)" "unprognostic (4.33e-3)" "unprognostic (1.31e-1)" "unprognostic (1.05e-1)" "unprognostic (3.01e-1)" "unprognostic (1.18e-1)" "unprognostic (1.28e-1)" "unprognostic (9.78e-3)" "unprognostic (4.66e-3)" "unprognostic (8.52e-3)" "unprognostic (4.91e-2)" "unprognostic (1.87e-1)" "unprognostic (3.60e-1)" "unprognostic (2.25e-1)" "unprognostic (1.23e-1)" "unprognostic (1.93e-1)" "unprognostic (2.73e-2)" "unprognostic (2.94e-1)" PRPF19 "hPSO4, NMP200, PRP19, PSO4, SNEV, UBOX4" ENSG00000110107 "Pre-mRNA processing factor 19" Q9UMS4 11 60890547-60906585 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, mRNA processing, mRNA splicing, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 117.6;Migrating cytotrophoblasts: 122.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012448, HPA038051, HPA059070" Supported Enhanced "Nuclear speckles" NA NA 78000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 2: Non-specific - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 197 "Nuclear speckles" "CAB012448: , HPA038051: , HPA059070: " "unprognostic (6.99e-3)" "unprognostic (4.63e-2)" "unprognostic (2.45e-1)" "unprognostic (1.33e-1)" "unprognostic (4.66e-2)" "unprognostic (3.25e-1)" "unprognostic (1.90e-1)" "unprognostic (9.68e-2)" "unprognostic (1.30e-3)" "unprognostic (1.45e-2)" "unprognostic (1.03e-1)" "unprognostic (8.84e-3)" "unprognostic (8.99e-2)" "validated prognostic unfavorable (4.14e-6)" "validated prognostic unfavorable (5.03e-5)" "unprognostic (4.44e-3)" "potential prognostic unfavorable (2.15e-4)" "unprognostic (1.37e-1)" "unprognostic (1.39e-2)" "unprognostic (1.34e-1)" "unprognostic (4.89e-2)" "unprognostic (9.50e-2)" "unprognostic (1.32e-1)" "unprognostic (1.82e-1)" "unprognostic (2.60e-1)" "unprognostic (3.86e-1)" "unprognostic (1.56e-1)" "unprognostic (1.27e-1)" "unprognostic (1.01e-1)" "unprognostic (4.55e-1)" "unprognostic (1.08e-1)" PRPF3 "hPrp3, Prp3, RP18, SNRNP90" ENSG00000117360 "Pre-mRNA processing factor 3" O43395 1 150321479-150353233 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027226, HPA067116" Approved Enhanced Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 49: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 45: Non-specific - Nuclear processes" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 174 Nucleoplasm "HPA027226: , HPA067116: " "unprognostic (1.77e-1)" "unprognostic (7.36e-2)" "unprognostic (4.99e-2)" "unprognostic (1.67e-1)" "unprognostic (2.61e-1)" "unprognostic (7.60e-2)" "unprognostic (3.46e-1)" "unprognostic (4.41e-2)" "unprognostic (6.25e-2)" "unprognostic (3.84e-2)" "unprognostic (3.74e-1)" "unprognostic (8.27e-2)" "unprognostic (1.13e-1)" "potential prognostic unfavorable (2.60e-6)" "unprognostic (3.51e-1)" "unprognostic (9.16e-2)" "unprognostic (1.16e-2)" "unprognostic (3.44e-2)" "unprognostic (4.95e-3)" "unprognostic (5.24e-2)" "unprognostic (2.12e-2)" "unprognostic (1.36e-1)" "unprognostic (1.29e-3)" "unprognostic (2.98e-2)" "unprognostic (5.32e-3)" "unprognostic (4.51e-2)" "unprognostic (1.01e-1)" "unprognostic (1.74e-2)" "unprognostic (4.23e-1)" "unprognostic (1.87e-1)" "unprognostic (1.78e-1)" PRPF31 "hPrp31, NY-BR-99, PRP31, RP11, SNRNP61" ENSG00000105618 "Pre-mRNA processing factor 31" Q8WWY3 19 54115410-54131719 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 30.3;Tuft cells: 34.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041939, HPA061873" Supported Supported Nucleoplasm NA NA 12000 "Cluster 13: Non-specific - Mitochondria" "Cluster 24: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 98: Neurons - Neurotransmission & signaling" 186 Nucleoplasm "HPA041939: , HPA061873: " "unprognostic (2.61e-1)" "unprognostic (8.02e-2)" "unprognostic (2.59e-2)" "unprognostic (2.27e-2)" "unprognostic (1.73e-1)" "unprognostic (4.57e-2)" "unprognostic (3.59e-1)" "unprognostic (7.64e-2)" "unprognostic (1.25e-1)" "unprognostic (1.05e-1)" "unprognostic (2.56e-3)" "unprognostic (1.90e-2)" "unprognostic (2.21e-2)" "potential prognostic unfavorable (1.73e-5)" "unprognostic (3.38e-2)" "unprognostic (2.53e-2)" "unprognostic (1.09e-1)" "unprognostic (1.86e-1)" "unprognostic (2.11e-1)" "unprognostic (1.25e-1)" "unprognostic (1.48e-1)" "unprognostic (7.03e-2)" "unprognostic (3.02e-1)" "unprognostic (2.60e-2)" "unprognostic (1.55e-1)" "unprognostic (2.24e-2)" "unprognostic (5.29e-2)" "unprognostic (1.27e-1)" "unprognostic (6.40e-2)" "unprognostic (3.78e-1)" "unprognostic (2.01e-1)" PRPF38A "FLJ14936, Prp38" ENSG00000134748 "Pre-mRNA processing factor 38A" Q8NAV1 1 52404602-52420836 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053099, HPA058407" Uncertain Enhanced Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 38 Nucleoplasm "HPA053099: , HPA058407: " "unprognostic (3.63e-2)" "unprognostic (2.24e-1)" "unprognostic (4.11e-1)" "unprognostic (2.88e-1)" "potential prognostic favorable (6.83e-4)" "unprognostic (7.39e-2)" "unprognostic (1.46e-2)" "unprognostic (3.61e-1)" "unprognostic (2.29e-2)" "unprognostic (4.90e-2)" "potential prognostic favorable (3.21e-5)" "unprognostic (5.33e-3)" "unprognostic (7.81e-2)" "potential prognostic unfavorable (2.76e-5)" "unprognostic (7.30e-3)" "unprognostic (3.86e-1)" "unprognostic (2.92e-2)" "unprognostic (9.55e-2)" "unprognostic (1.28e-2)" "unprognostic (1.07e-1)" "unprognostic (9.42e-2)" "unprognostic (8.25e-2)" "unprognostic (3.41e-2)" "unprognostic (4.50e-2)" "unprognostic (7.57e-2)" "unprognostic (5.75e-2)" "unprognostic (6.27e-3)" "unprognostic (7.91e-2)" "unprognostic (1.52e-1)" "unprognostic (1.32e-1)" "unprognostic (1.77e-1)" PRPF38B "FLJ10330, NET1" ENSG00000134186 "Pre-mRNA processing factor 38B" Q5VTL8 1 108692310-108702928 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA053255 Approved NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 9: T-cells - Adaptive immunity: Regulation" 4 "HPA053255: " "unprognostic (5.28e-3)" "unprognostic (4.27e-2)" "unprognostic (1.86e-1)" "unprognostic (1.23e-1)" "unprognostic (1.57e-1)" "unprognostic (8.81e-3)" "unprognostic (4.10e-3)" "unprognostic (6.13e-2)" "unprognostic (5.62e-2)" "unprognostic (1.05e-3)" "unprognostic (5.81e-2)" "unprognostic (8.06e-3)" "unprognostic (8.61e-2)" "potential prognostic unfavorable (4.04e-4)" "unprognostic (5.53e-2)" "unprognostic (2.10e-1)" "unprognostic (1.77e-2)" "unprognostic (8.80e-3)" "unprognostic (1.96e-2)" "unprognostic (4.76e-2)" "unprognostic (1.35e-1)" "unprognostic (9.49e-2)" "unprognostic (2.45e-2)" "unprognostic (4.57e-2)" "unprognostic (3.45e-2)" "unprognostic (2.60e-1)" "unprognostic (8.37e-2)" "unprognostic (8.88e-2)" "unprognostic (4.07e-1)" "unprognostic (1.94e-1)" "unprognostic (3.52e-2)" PRPF39 "FLJ11128, FLJ20666" ENSG00000185246 "Pre-mRNA processing factor 39" Q86UA1 14 45084107-45116282 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 7.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001176, HPA078403" Approved Approved Nucleoplasm NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 38: Non-specific - Transcription" "Cluster 9: T-cells - Adaptive immunity: Regulation" 6 Nucleoplasm "HPA001176: , HPA078403: " "unprognostic (9.75e-3)" "unprognostic (1.22e-2)" "unprognostic (1.70e-1)" "unprognostic (5.75e-2)" "unprognostic (1.28e-1)" "unprognostic (1.82e-1)" "unprognostic (1.55e-1)" "unprognostic (5.50e-3)" "unprognostic (2.06e-1)" "potential prognostic favorable (4.10e-4)" "potential prognostic favorable (9.78e-7)" "unprognostic (5.26e-2)" "unprognostic (1.90e-1)" "unprognostic (2.16e-1)" "unprognostic (7.96e-2)" "unprognostic (1.79e-2)" "unprognostic (4.91e-2)" "unprognostic (1.02e-1)" "unprognostic (4.04e-2)" "unprognostic (2.82e-1)" "unprognostic (2.81e-3)" "unprognostic (4.91e-2)" "unprognostic (2.15e-1)" "unprognostic (2.06e-1)" "unprognostic (2.96e-1)" "unprognostic (2.84e-1)" "unprognostic (2.89e-1)" "unprognostic (2.73e-2)" PRPF4 "HPRP4, HPRP4P, PRP4, Prp4p, SNRNP60" ENSG00000136875 "Pre-mRNA processing factor 4" O43172 9 113275642-113294009 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021794, HPA022248" Enhanced Enhanced "Nuclear speckles" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 17: Non-specific - RNA processing" 95 "Nuclear speckles" "HPA021794: , HPA022248: " "unprognostic (3.65e-2)" "unprognostic (6.06e-2)" "unprognostic (5.37e-1)" "unprognostic (2.66e-1)" "unprognostic (2.24e-1)" "unprognostic (5.40e-2)" "unprognostic (4.26e-1)" "unprognostic (5.92e-3)" "unprognostic (1.00e-2)" "unprognostic (5.75e-2)" "potential prognostic favorable (7.09e-6)" "unprognostic (8.48e-3)" "unprognostic (1.99e-1)" "unprognostic (1.86e-3)" "unprognostic (2.28e-3)" "potential prognostic unfavorable (4.70e-4)" "unprognostic (6.49e-3)" "unprognostic (1.84e-1)" "unprognostic (2.28e-2)" "unprognostic (9.85e-2)" "unprognostic (3.88e-1)" "unprognostic (4.74e-2)" "unprognostic (2.88e-1)" "unprognostic (5.50e-2)" "unprognostic (4.63e-3)" "unprognostic (2.71e-1)" "unprognostic (9.82e-2)" "unprognostic (1.96e-1)" "unprognostic (1.96e-1)" "unprognostic (4.83e-2)" "unprognostic (7.76e-2)" PRPF40A "FBP-11, FBP11, FLAF1, FLJ20585, FNBP3, HIP10, HYPA, NY-REN-6, Prp40" ENSG00000196504 "Pre-mRNA processing factor 40 homolog A" 2 152651593-152718012 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038272, HPA038273" Approved Enhanced "Nuclear speckles" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 17: Non-specific - RNA processing" 84 "Nuclear speckles" "HPA038272: , HPA038273: " "unprognostic (3.47e-1)" "unprognostic (9.36e-2)" "unprognostic (3.52e-2)" "unprognostic (1.92e-2)" "unprognostic (7.13e-2)" "unprognostic (1.48e-2)" "unprognostic (1.38e-2)" "unprognostic (8.70e-3)" "unprognostic (1.34e-1)" "potential prognostic unfavorable (4.70e-4)" "potential prognostic favorable (8.93e-6)" "unprognostic (3.49e-2)" "unprognostic (1.56e-3)" "unprognostic (3.13e-3)" "unprognostic (2.72e-2)" "unprognostic (9.08e-2)" "unprognostic (1.50e-2)" "unprognostic (5.65e-2)" "unprognostic (2.76e-2)" "unprognostic (1.76e-1)" "unprognostic (1.41e-2)" "validated prognostic unfavorable (4.65e-5)" "validated prognostic unfavorable (7.39e-4)" "unprognostic (1.04e-1)" "unprognostic (6.08e-2)" "unprognostic (9.45e-2)" "unprognostic (7.76e-2)" "unprognostic (2.12e-1)" "unprognostic (2.02e-1)" "unprognostic (3.31e-3)" "unprognostic (9.65e-2)" PRPF40B HYPC ENSG00000110844 "Pre-mRNA processing factor 40 homolog B" Q6NWY9 12 49568218-49644666 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Myonuclei: 156.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Spleen - Endothelial cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038426, HPA038599" Enhanced Approved "Nucleoplasm,Nuclear bodies,Aggresome,Cytosol" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 21: Testis - Mixed function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 6 "Nuclear bodies" "Nucleoplasm, Aggresome, Cytosol" "HPA038426: , HPA038599: " "unprognostic (1.44e-1)" "unprognostic (3.27e-2)" "unprognostic (8.74e-2)" "unprognostic (2.31e-2)" "unprognostic (1.52e-1)" "unprognostic (5.69e-2)" "unprognostic (2.52e-1)" "unprognostic (7.01e-2)" "unprognostic (2.05e-1)" "unprognostic (7.26e-2)" "unprognostic (3.51e-3)" "unprognostic (1.58e-2)" "potential prognostic favorable (6.77e-4)" "potential prognostic unfavorable (1.04e-5)" "unprognostic (1.08e-1)" "unprognostic (5.41e-2)" "unprognostic (9.70e-2)" "unprognostic (2.62e-1)" "unprognostic (2.09e-2)" "unprognostic (1.35e-1)" "unprognostic (1.62e-2)" "unprognostic (3.67e-3)" "unprognostic (2.58e-2)" "unprognostic (3.79e-2)" "unprognostic (1.33e-2)" "unprognostic (1.13e-1)" "unprognostic (2.16e-2)" "unprognostic (1.55e-2)" "unprognostic (1.90e-2)" "unprognostic (1.17e-1)" "unprognostic (2.36e-1)" PRPF4B "KIAA0536, PR4H, Prp4" ENSG00000112739 "Pre-mRNA processing factor 4B" Q13523 6 4021267-4064983 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020638 Approved Supported "Nuclear speckles" NA NA 920000 "Cluster 54: Non-specific - Ribosome" "Cluster 55: Non-specific - Transcription" "Cluster 56: Non-specific - Sensory perception" "Cluster 17: Non-specific - RNA processing" 162 "Nuclear speckles" "HPA020638: " "unprognostic (4.91e-2)" "unprognostic (5.06e-2)" "unprognostic (2.41e-1)" "unprognostic (1.56e-1)" "unprognostic (1.13e-2)" "unprognostic (6.44e-2)" "unprognostic (1.05e-1)" "unprognostic (7.51e-2)" "potential prognostic favorable (6.10e-4)" "unprognostic (2.23e-1)" "potential prognostic unfavorable (4.25e-4)" "unprognostic (2.59e-1)" "unprognostic (2.38e-1)" "unprognostic (3.73e-3)" "unprognostic (5.64e-1)" "unprognostic (6.65e-2)" "unprognostic (1.31e-1)" "unprognostic (3.58e-2)" "potential prognostic favorable (3.24e-4)" "unprognostic (7.23e-2)" "unprognostic (3.52e-2)" "unprognostic (2.48e-1)" "unprognostic (1.79e-2)" "unprognostic (2.47e-2)" "unprognostic (5.25e-3)" "unprognostic (6.06e-2)" "unprognostic (3.16e-2)" "unprognostic (1.92e-1)" "unprognostic (5.36e-1)" "unprognostic (7.69e-2)" "unprognostic (1.85e-2)" PRPF6 "ANT-1, bB152O15.1, C20orf14, hPrp6, Prp6, RP60, SNRNP102, TOM, U5-102K" ENSG00000101161 "Pre-mRNA processing factor 6" O94906 20 63981132-64033100 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047106 Supported Supported "Nucleoplasm,Nuclear speckles,Vesicles,Centrosome,Basal body,Cytosol" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 24: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 17: Non-specific - RNA processing" 142 "Nucleoplasm, Nuclear speckles, Basal body" "Vesicles, Centrosome, Cytosol" "HPA047106: " "unprognostic (8.07e-2)" "unprognostic (1.43e-1)" "unprognostic (1.77e-1)" "unprognostic (5.63e-2)" "unprognostic (2.49e-1)" "unprognostic (3.74e-2)" "unprognostic (1.86e-1)" "unprognostic (1.10e-1)" "unprognostic (7.99e-2)" "unprognostic (4.67e-3)" "potential prognostic favorable (4.07e-5)" "unprognostic (5.30e-2)" "unprognostic (1.41e-1)" "potential prognostic unfavorable (3.16e-4)" "unprognostic (9.04e-3)" "unprognostic (6.93e-2)" "unprognostic (8.75e-2)" "unprognostic (1.59e-1)" "unprognostic (7.90e-2)" "unprognostic (4.92e-2)" "unprognostic (7.43e-2)" "unprognostic (1.71e-3)" "unprognostic (2.51e-2)" "unprognostic (8.10e-2)" "unprognostic (2.09e-2)" "unprognostic (6.28e-3)" "unprognostic (1.25e-1)" "unprognostic (5.15e-2)" "unprognostic (4.48e-1)" "unprognostic (7.66e-2)" "unprognostic (2.55e-1)" PRPF8 "hPrp8, Prp8, PRPC8, RP13, SNRNP220" ENSG00000174231 "Pre-mRNA processing factor 8" Q6P2Q9 17 1650629-1684867 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Cancer-related genes, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009941, CAB015457, HPA075655" Supported Supported "Nucleoplasm,Nuclear speckles" NA NA 200000 "Cluster 13: Non-specific - Mitochondria" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 42: Non-specific - Unknown function" "Cluster 102: Non-specific - Mixed function" 252 "Nucleoplasm, Nuclear speckles" "CAB009941: , CAB015457: , HPA075655: " "unprognostic (1.43e-1)" "unprognostic (3.77e-1)" "unprognostic (4.66e-2)" "unprognostic (2.62e-2)" "unprognostic (2.82e-2)" "unprognostic (1.35e-1)" "unprognostic (3.63e-2)" "unprognostic (1.52e-1)" "unprognostic (2.40e-1)" "unprognostic (4.51e-2)" "unprognostic (1.05e-2)" "unprognostic (1.32e-3)" "unprognostic (2.28e-2)" "unprognostic (1.01e-2)" "unprognostic (1.06e-1)" "unprognostic (3.51e-2)" "unprognostic (7.95e-2)" "unprognostic (1.64e-1)" "unprognostic (9.79e-2)" "unprognostic (2.05e-1)" "unprognostic (2.47e-1)" "potential prognostic favorable (2.34e-5)" "unprognostic (3.97e-2)" "unprognostic (3.04e-1)" "unprognostic (2.29e-1)" "unprognostic (4.29e-2)" "unprognostic (1.13e-2)" "unprognostic (1.36e-1)" "unprognostic (1.68e-1)" "unprognostic (7.39e-2)" "unprognostic (6.38e-2)" PRPH "NEF4, PRPH1" ENSG00000135406 Peripherin P41219 12 49295147-49298686 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 30.8;testis: 16.3" "Cell type enhanced" "Detected in some" "Early spermatids: 298.2;Late primary spermatocytes: 367.2;Late spermatids: 1452.4" "Cell type enhanced" "Detected in some" "lower rhombic lip: 1.2;splatter: 3.2" "Group enriched" "Detected in many" 4 "Glioblastoma Multiforme (TCGA): 7.8;Pancreatic Adenocarcinoma (TCGA): 7.0;Testicular Germ Cell Tumor (TCGA): 10.4;Uterine Corpus Endometrial Carcinoma (TCGA): 11.5" "Group enriched" "Detected in many" 4 "medulla oblongata: 100.9;pons: 105.4;white matter: 29.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 11 "Neuroblastoma: 158.4;Rhabdoid: 80.6" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Stomach - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Fibroblasts" "Group enriched" "Detected in many" 4 "hypothalamus: 19.4;pons and medulla: 35.1" "Region enriched" "Detected in all" 8 "spinal cord: 346.7" "CAB002437, HPA039277, HPA063887" Enhanced NA NA "Cluster 21: Testis - Mixed function" "Cluster 43: Hindbrain - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 79 "CAB002437: , HPA039277: , HPA063887: " "unprognostic (2.77e-1)" "unprognostic (9.43e-2)" "unprognostic (5.54e-2)" "unprognostic (1.22e-1)" "potential prognostic unfavorable (2.25e-5)" "unprognostic (5.62e-2)" "unprognostic (4.17e-2)" "unprognostic (2.58e-1)" "unprognostic (1.41e-1)" "unprognostic (8.02e-2)" "unprognostic (1.83e-1)" "unprognostic (5.29e-2)" "unprognostic (8.54e-2)" "unprognostic (1.49e-2)" "unprognostic (8.19e-2)" "unprognostic (6.07e-2)" PRPH2 "CACD2, rd2, RDS, RP7, TSPAN22" ENSG00000112619 "Peripherin 2" P23942 6 42696598-42722597 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Cell adhesion, Sensory transduction, Vision" "Cone-rod dystrophy, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 48 "retina: 594.9" "Group enriched" "Detected in many" 13 "Cone photoreceptor cells: 517.5;Rod photoreceptor cells: 1418.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 2.5;Sarcoma: 1.5" "Prostate - Fibroblasts, Stomach - Fibroblasts" "Region enriched" "Detected in single" 7 "hippocampal formation: 2.4" "Not detected" "Not detected" HPA029458 Enhanced NA NA "Cluster 42: Retina - Visual perception" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 1: Neuronal - Visual perception" "Cluster 79: Photoreceptor cells - Phototransduction" 2 "HPA029458: " "unprognostic (2.25e-2)" "unprognostic (2.24e-2)" "unprognostic (9.99e-2)" "unprognostic (3.14e-2)" "unprognostic (1.75e-1)" "unprognostic (1.26e-1)" "unprognostic (3.62e-2)" "unprognostic (2.52e-1)" "unprognostic (1.19e-1)" PRPS1 "CMTX5, DFN2, DFNX1, PPRibP, PRS-I" ENSG00000147224 "Phosphoribosyl pyrophosphate synthetase 1" P60891 X 107628428-107651993 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Nucleotide biosynthesis" "Kinase, Transferase" "Charcot-Marie-Tooth disease, Deafness, Disease variant, Gout, Intellectual disability, Neurodegeneration, Neuropathy, Non-syndromic deafness, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epicardial cells: 70.5;Erythrocyte progenitors: 75.2;Hepatocytes: 67.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043760, HPA051269" Uncertain Approved Vesicles NA NA 590000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 118 Vesicles "HPA043760: , HPA051269: " "unprognostic (2.75e-1)" "unprognostic (5.97e-2)" "unprognostic (3.92e-1)" "unprognostic (1.64e-2)" "unprognostic (1.38e-1)" "unprognostic (3.15e-3)" "unprognostic (9.18e-3)" "potential prognostic favorable (3.80e-5)" "unprognostic (6.05e-3)" "potential prognostic unfavorable (3.65e-5)" "potential prognostic favorable (1.18e-4)" "unprognostic (2.62e-1)" "unprognostic (2.04e-1)" "unprognostic (1.46e-2)" "unprognostic (9.79e-3)" "unprognostic (3.41e-2)" "unprognostic (2.01e-3)" "unprognostic (1.71e-2)" "unprognostic (3.38e-1)" "unprognostic (3.70e-1)" "unprognostic (4.99e-2)" "unprognostic (3.97e-2)" "unprognostic (2.06e-1)" "unprognostic (8.11e-2)" "unprognostic (1.70e-1)" "unprognostic (5.21e-2)" "unprognostic (9.15e-3)" "unprognostic (2.05e-1)" "unprognostic (7.59e-2)" "unprognostic (4.53e-2)" "unprognostic (1.63e-2)" PRPS1L1 "PRPS3, PRPSL" ENSG00000229937 "Phosphoribosyl pyrophosphate synthetase 1 like 1" P21108 7 18026770-18027846 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Nucleotide biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 295 "testis: 29.4" "Cell type enriched" "Detected in some" 5 "Late primary spermatocytes: 276.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" HPA051269 Uncertain Vesicles NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 20 Vesicles "HPA051269: " PRPS2 ENSG00000101911 "Phosphoribosyl pyrophosphate synthetase 2" P11908 X 12791355-12824222 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Nucleotide biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 141.8;parathyroid gland: 171.4" "Cell type enhanced" "Detected in many" "Breast lactating cells: 286.2;Decidual stromal cells: 521.1;Leydig cells: 1809.4;Parietal cells: 341.2;Peritubular myoid cells: 2294.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051269, HPA067599, CAB070417" Enhanced Approved "Nuclear speckles,Vesicles,Basal body" NA NA 370000 "Cluster 18: Non-specific - Translation" "Cluster 61: Non-specific - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 36: Non-specific - mRNA processing" "Cluster 94: Gonadal somatic cells - Mixed function" 28 Vesicles "Nuclear speckles, Basal body" "CAB070417: , HPA051269: , HPA067599: " "unprognostic (5.52e-3)" "unprognostic (2.57e-1)" "unprognostic (3.09e-1)" "unprognostic (3.31e-2)" "unprognostic (8.06e-3)" "unprognostic (3.23e-1)" "unprognostic (5.18e-2)" "potential prognostic unfavorable (3.80e-4)" "unprognostic (3.42e-3)" "unprognostic (2.67e-2)" "potential prognostic favorable (1.17e-6)" "unprognostic (2.83e-1)" "unprognostic (4.42e-2)" "unprognostic (1.35e-2)" "unprognostic (2.54e-3)" "unprognostic (2.70e-2)" "unprognostic (4.70e-3)" "unprognostic (7.94e-2)" "unprognostic (7.34e-2)" "unprognostic (5.37e-2)" "unprognostic (8.61e-2)" "unprognostic (4.31e-3)" "unprognostic (3.75e-1)" "unprognostic (5.70e-2)" "unprognostic (2.76e-2)" "unprognostic (9.72e-3)" "unprognostic (1.20e-2)" "unprognostic (3.25e-1)" "unprognostic (1.14e-1)" "unprognostic (4.58e-2)" "unprognostic (2.36e-1)" PRPSAP1 PAP39 ENSG00000161542 "Phosphoribosyl pyrophosphate synthetase associated protein 1" Q14558 17 76309478-76384521 "Predicted intracellular proteins" "Nucleotide biosynthesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 251.0;Müller glia: 211.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062396 Approved Cytosol NA NA 89000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 49: Hindbrain - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 11: Muller glia cells - Retinal homeostasis" 14 Cytosol "HPA062396: " "unprognostic (2.48e-1)" "unprognostic (2.97e-1)" "unprognostic (1.02e-1)" "unprognostic (2.14e-2)" "unprognostic (6.06e-3)" "unprognostic (4.30e-2)" "unprognostic (1.28e-1)" "unprognostic (5.99e-2)" "unprognostic (5.40e-2)" "potential prognostic unfavorable (2.60e-4)" "unprognostic (2.11e-3)" "unprognostic (1.72e-2)" "unprognostic (1.21e-1)" "unprognostic (7.77e-2)" "unprognostic (8.43e-2)" "unprognostic (2.34e-3)" "potential prognostic unfavorable (3.93e-5)" "unprognostic (2.00e-1)" "unprognostic (1.32e-3)" "unprognostic (2.46e-1)" "unprognostic (1.32e-1)" "unprognostic (5.62e-2)" "unprognostic (1.16e-2)" "unprognostic (1.42e-2)" "unprognostic (7.64e-3)" "unprognostic (2.85e-1)" "unprognostic (3.70e-2)" "unprognostic (1.46e-2)" "unprognostic (1.97e-1)" "unprognostic (3.65e-2)" "unprognostic (2.43e-3)" PRPSAP2 PAP41 ENSG00000141127 "Phosphoribosyl pyrophosphate synthetase associated protein 2" O60256 17 18840085-18931287 "Predicted intracellular proteins" "Nucleotide biosynthesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "testis cancer: 252.7" "Spleen - B-cells (Spleen), Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021881 Approved Approved Nucleoplasm,Cytosol NA NA 79000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 55: Non-specific - Transcription" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 20 "Nucleoplasm, Cytosol" "HPA021881: " "unprognostic (1.50e-1)" "unprognostic (1.43e-1)" "potential prognostic unfavorable (9.22e-4)" "unprognostic (8.65e-2)" "unprognostic (1.61e-1)" "potential prognostic unfavorable (6.34e-4)" "unprognostic (1.33e-1)" "potential prognostic favorable (2.71e-4)" "unprognostic (1.56e-1)" "unprognostic (8.77e-2)" "validated prognostic favorable (4.82e-7)" "validated prognostic favorable (3.56e-4)" "unprognostic (1.17e-1)" "unprognostic (8.91e-3)" "unprognostic (7.70e-2)" "unprognostic (1.07e-1)" "unprognostic (1.54e-1)" "unprognostic (6.46e-2)" "unprognostic (3.59e-2)" "unprognostic (3.84e-1)" "unprognostic (2.21e-1)" "unprognostic (5.05e-3)" "unprognostic (6.08e-2)" "unprognostic (2.18e-2)" "unprognostic (2.05e-1)" "unprognostic (3.91e-1)" "unprognostic (2.79e-2)" "unprognostic (1.59e-1)" "unprognostic (1.04e-1)" "unprognostic (1.62e-1)" "unprognostic (5.21e-2)" PRR11 FLJ11029 ENSG00000068489 "Proline rich 11" Q96HE9 17 59155732-59206709 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.0;lymphoid tissue: 19.1" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 26.3;Extravillous trophoblasts: 12.2;Hematopoietic stem cells: 34.9;Megakaryocyte progenitors: 40.5;Megakaryocyte-Erythroid progenitors: 24.7;Monocyte progenitors: 44.0;Neutrophil progenitors: 17.3" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 13.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 9.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA023923, HPA052376" Uncertain Approved "Endoplasmic reticulum" Yes Yes "Cluster 25: Non-specific - Unknown function" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 48: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 4 "Endoplasmic reticulum" "HPA023923: , HPA052376: " "unprognostic (2.42e-1)" "unprognostic (2.68e-2)" "unprognostic (2.22e-1)" "unprognostic (6.41e-3)" "unprognostic (9.33e-2)" "unprognostic (8.61e-2)" "unprognostic (1.94e-1)" "unprognostic (2.20e-1)" "unprognostic (1.80e-2)" "potential prognostic unfavorable (5.78e-5)" "potential prognostic unfavorable (5.86e-5)" "unprognostic (1.39e-2)" "potential prognostic unfavorable (8.25e-6)" "validated prognostic unfavorable (3.80e-7)" "validated prognostic unfavorable (1.25e-7)" "potential prognostic unfavorable (7.56e-6)" "unprognostic (1.09e-3)" "unprognostic (8.30e-3)" "unprognostic (3.53e-1)" "unprognostic (2.11e-1)" "unprognostic (4.74e-1)" "unprognostic (1.30e-3)" "unprognostic (2.30e-3)" "unprognostic (2.38e-1)" "unprognostic (9.30e-2)" "unprognostic (1.54e-2)" "unprognostic (4.48e-3)" "unprognostic (9.41e-2)" "unprognostic (1.18e-1)" "unprognostic (1.07e-2)" "unprognostic (9.37e-2)" PRR12 KIAA1205 ENSG00000126464 "Proline rich 12" Q9ULL5 19 49591182-49626439 "Disease related genes, Predicted intracellular proteins" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011959 Approved Approved Cytosol NA NA "Cluster 64: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 7 Cytosol "HPA011959: " "unprognostic (2.74e-2)" "unprognostic (1.64e-1)" "unprognostic (5.65e-2)" "unprognostic (1.02e-2)" "unprognostic (1.32e-1)" "unprognostic (1.35e-1)" "unprognostic (5.07e-1)" "unprognostic (3.60e-2)" "unprognostic (1.37e-2)" "unprognostic (1.58e-1)" "unprognostic (8.51e-2)" "unprognostic (4.44e-1)" "unprognostic (4.80e-2)" "unprognostic (4.58e-3)" "unprognostic (3.17e-1)" "unprognostic (9.43e-2)" "unprognostic (3.10e-1)" "unprognostic (1.93e-1)" "unprognostic (3.36e-1)" "unprognostic (4.63e-2)" "unprognostic (1.11e-1)" "unprognostic (4.23e-2)" "unprognostic (1.92e-2)" "unprognostic (4.29e-3)" "unprognostic (4.13e-1)" "unprognostic (2.33e-2)" "unprognostic (5.96e-2)" "unprognostic (3.23e-2)" "unprognostic (3.77e-1)" "unprognostic (2.56e-2)" "unprognostic (3.27e-2)" PRR13 "DKFZP564J157, FLJ23818" ENSG00000205352 "Proline rich 13" Q9NZ81 12 53441678-53446645 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 32.5;Enterocytes: 44.4;Neutrophils: 49.7;Oocytes: 32.2;Parietal cells: 31.8;Proximal tubule cells: 36.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Macrophages, Heart muscle - Macrophages, Spleen - Neutrophils_2, Testis - Leydig cells" "Low region specificity" "Detected in all" "HPA039396, HPA046219" Uncertain Supported Nucleoplasm,Vesicles,Cytosol NA Yes "Cluster 7: Non-specific - Innate immune response" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 38: Non-specific - Transcription" "Cluster 98: Neurons - Neurotransmission & signaling" 38 Nucleoplasm "Vesicles, Cytosol" "HPA039396: , HPA046219: " "unprognostic (1.13e-1)" "unprognostic (1.65e-3)" "unprognostic (2.21e-1)" "unprognostic (2.73e-2)" "unprognostic (4.99e-2)" "unprognostic (9.12e-2)" "unprognostic (9.88e-3)" "unprognostic (1.56e-3)" "unprognostic (7.45e-3)" "unprognostic (1.03e-1)" "unprognostic (6.99e-2)" "unprognostic (1.23e-2)" "unprognostic (3.57e-1)" "validated prognostic unfavorable (2.71e-5)" "validated prognostic unfavorable (5.36e-5)" "unprognostic (1.10e-2)" "unprognostic (5.32e-3)" "unprognostic (9.73e-2)" "unprognostic (8.74e-3)" "unprognostic (6.44e-2)" "unprognostic (3.58e-1)" "unprognostic (3.66e-3)" "unprognostic (5.93e-2)" "unprognostic (7.51e-2)" "unprognostic (3.10e-1)" "unprognostic (3.15e-3)" "unprognostic (2.38e-1)" "unprognostic (1.20e-1)" "unprognostic (3.76e-2)" "unprognostic (1.09e-1)" "unprognostic (2.07e-1)" PRR14 MGC3121 ENSG00000156858 "Proline rich 14" Q9BWN1 16 30650717-30656413 "Predicted intracellular proteins" Myogenesis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052022, HPA060265, HPA075914" Uncertain Enhanced Nucleoplasm NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 54: Non-specific - Transcription" "Cluster 9: T-cells - Adaptive immunity: Regulation" 21 Nucleoplasm "HPA052022: , HPA060265: , HPA075914: " "unprognostic (1.64e-1)" "unprognostic (9.56e-2)" "unprognostic (2.35e-1)" "unprognostic (8.22e-2)" "unprognostic (4.62e-2)" "unprognostic (7.21e-2)" "unprognostic (1.23e-1)" "unprognostic (3.04e-2)" "unprognostic (7.21e-2)" "unprognostic (1.05e-1)" "potential prognostic favorable (2.15e-4)" "unprognostic (1.43e-1)" "unprognostic (6.39e-2)" "unprognostic (8.47e-3)" "unprognostic (1.05e-1)" "unprognostic (8.78e-3)" "unprognostic (4.69e-2)" "unprognostic (5.65e-2)" "unprognostic (8.78e-2)" "unprognostic (1.05e-1)" "unprognostic (3.25e-2)" "unprognostic (7.63e-2)" "unprognostic (3.90e-2)" "unprognostic (3.27e-2)" "unprognostic (1.23e-1)" "unprognostic (3.33e-2)" "unprognostic (5.07e-2)" "unprognostic (1.80e-1)" "unprognostic (1.37e-1)" "unprognostic (1.19e-1)" "unprognostic (1.22e-2)" PRR14L "C22orf30, MGC50372" ENSG00000183530 "Proline rich 14 like" Q5THK1 22 31676256-31750140 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062645 Uncertain Approved Nucleoplasm NA NA "Cluster 41: Basophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 7: Non-specific - Transcription" 4 Nucleoplasm "HPA062645: " "unprognostic (3.56e-3)" "unprognostic (1.90e-1)" "unprognostic (6.01e-2)" "unprognostic (1.44e-1)" "unprognostic (4.66e-2)" "unprognostic (2.34e-2)" "unprognostic (5.62e-2)" "unprognostic (2.11e-1)" "unprognostic (3.66e-2)" "potential prognostic favorable (1.80e-5)" "unprognostic (3.85e-3)" "unprognostic (1.92e-1)" "unprognostic (1.47e-2)" "unprognostic (3.45e-1)" "unprognostic (2.45e-1)" "unprognostic (2.92e-2)" "unprognostic (4.30e-2)" "unprognostic (1.79e-3)" "unprognostic (1.65e-1)" "unprognostic (3.91e-1)" "unprognostic (9.60e-2)" "unprognostic (1.59e-2)" "unprognostic (1.73e-1)" "unprognostic (5.95e-3)" "unprognostic (1.74e-2)" "unprognostic (2.14e-2)" "unprognostic (1.12e-1)" "unprognostic (2.19e-1)" "unprognostic (5.95e-2)" "unprognostic (1.58e-1)" PRR15 ENSG00000176532 "Proline rich 15" Q8IV56 7 29563835-29567293 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 58.9;intestine: 76.2;stomach 1: 46.5" "Cell type enhanced" "Detected in many" "Colonocytes: 198.1;Conjunctival goblet cells: 55.3;Enteric transient amplifying cells: 56.7;Enterocytes: 113.0;Epididymal clear cells: 71.4;Epididymal efferent duct absorptive cells: 63.3;Epididymal principal cells: 74.4;Granulosa cells: 115.2;Oocytes: 92.1;Respiratory ciliated cells: 77.0;Respiratory deuterosomal cells: 90.2;Respiratory secretory cells: 129.3;Urothelial cells: 75.4" "Cell type enriched" "Detected in single" 4 "central nervous system macrophage: 4.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 75.5" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA040996, HPA048121" Enhanced Uncertain "Vesicles,Cell Junctions" NA NA "Cluster 77: Intestine - Digestion" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 1 Vesicles "Cell Junctions" "HPA040996: , HPA048121: " "unprognostic (3.06e-2)" "unprognostic (2.82e-1)" "unprognostic (5.10e-2)" "unprognostic (9.49e-2)" "unprognostic (2.16e-1)" "unprognostic (1.05e-2)" "unprognostic (7.96e-2)" "unprognostic (3.01e-2)" "unprognostic (5.28e-2)" "unprognostic (2.62e-3)" "unprognostic (3.16e-1)" "unprognostic (2.86e-1)" "unprognostic (2.04e-1)" "unprognostic (5.46e-2)" "unprognostic (1.22e-3)" "unprognostic (3.61e-1)" "unprognostic (5.74e-2)" "unprognostic (6.67e-2)" "unprognostic (1.58e-1)" "unprognostic (1.01e-2)" "potential prognostic unfavorable (2.51e-4)" "unprognostic (2.39e-3)" "unprognostic (8.95e-2)" "unprognostic (8.29e-2)" "unprognostic (2.78e-1)" "unprognostic (1.31e-2)" "unprognostic (1.70e-1)" "unprognostic (3.68e-3)" "unprognostic (4.74e-2)" PRR15L "ATAD4, MGC11242" ENSG00000167183 "Proline rich 15 like" Q9BU68 17 47951967-47957883 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 167.7;pancreas: 99.0;stomach 1: 80.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 96.0;Cholangiocytes: 78.7;Colonocytes: 188.2;Enteric stem cells: 105.7;Enteric transient amplifying cells: 104.7;Enterocytes: 242.7;Gastric chief cells: 67.7;Goblet cells: 120.2;Paneth cells: 89.0;Parietal cells: 132.6;Salivary duct cells: 81.9" "Cell type enriched" "Detected in single" 4 "choroid plexus epithelial cell: 3.6" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 8 "choroid plexus: 22.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 50.6;colorectal cancer: 47.9;Gastric cancer: 39.1" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Corticotropes, Skin - Eccrine sweat gland cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "Region enhanced" "Detected in many" "midbrain: 15.9" HPA022918 Approved Approved Cytosol No NA "Cluster 60: Stomach - Digestion" "Cluster 36: Choroid plexus - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" Cytosol "HPA022918: " "unprognostic (1.08e-1)" "unprognostic (1.92e-2)" "unprognostic (7.44e-2)" "unprognostic (1.49e-1)" "unprognostic (9.32e-2)" "unprognostic (8.52e-3)" "unprognostic (5.54e-2)" "unprognostic (1.85e-1)" "potential prognostic favorable (2.11e-5)" "unprognostic (1.39e-2)" "potential prognostic favorable (6.68e-4)" "unprognostic (2.76e-1)" "unprognostic (4.48e-3)" "unprognostic (1.07e-1)" "unprognostic (7.52e-2)" "unprognostic (1.08e-2)" "unprognostic (1.45e-1)" "unprognostic (9.83e-2)" "unprognostic (3.96e-2)" "unprognostic (4.54e-2)" "unprognostic (1.54e-3)" "unprognostic (3.12e-1)" "unprognostic (1.05e-1)" "unprognostic (6.70e-2)" "potential prognostic favorable (1.49e-4)" "unprognostic (1.45e-1)" "unprognostic (9.37e-2)" "unprognostic (2.88e-2)" PRR16 DSC54 ENSG00000184838 "Proline rich 16" Q569H4 5 120464300-120687332 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 28.3" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 160.5;Brain excitatory neurons: 250.4;Brain inhibitory neurons: 247.9;Cardiomyocytes: 172.6;Cone photoreceptor cells: 569.3;Endometrial stromal cells: 352.0;Fibroblasts: 144.6;Hematopoietic stem cells: 246.5;Myonuclei: 413.2;Other brain neurons: 194.3;Pericytes: 163.9;Retinal bipolar cells: 171.8;Retinal horizontal cells: 156.3;Somatotrophs: 199.7;Thymic myoid cells: 376.6" "Cell type enhanced" "Detected in all" "deep-layer near-projecting: 769.9" "Cancer enriched" "Detected in many" 6 "Prostate Adenocarcinoma (TCGA): 30.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049254 Approved Approved Nucleoplasm,Midbody,Cytosol Yes No "Cluster 40: Monocytes - Innate immune response" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 5 Nucleoplasm "Midbody, Cytosol" "HPA049254: " "unprognostic (4.32e-1)" "unprognostic (8.28e-2)" "unprognostic (1.80e-1)" "unprognostic (1.79e-1)" "unprognostic (1.74e-1)" "unprognostic (1.26e-1)" "unprognostic (4.78e-1)" "unprognostic (3.43e-3)" "unprognostic (8.58e-2)" "unprognostic (2.63e-1)" "unprognostic (6.98e-2)" "unprognostic (3.88e-2)" "unprognostic (9.59e-3)" "unprognostic (3.02e-3)" "unprognostic (1.01e-1)" "unprognostic (7.27e-2)" "unprognostic (3.98e-2)" "unprognostic (3.83e-2)" "unprognostic (2.83e-2)" "unprognostic (1.90e-1)" "unprognostic (2.09e-1)" "unprognostic (5.33e-2)" "unprognostic (9.40e-2)" "unprognostic (9.60e-3)" "unprognostic (3.81e-2)" "unprognostic (2.76e-2)" PRR18 MGC35308 ENSG00000176381 "Proline rich 18" Q8N4B5 6 166305300-166308448 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "brain: 50.1" "Cell type enriched" "Detected in some" 4 "Oligodendrocytes: 74.5" "Group enriched" "Detected in many" 4 "committed oligodendrocyte precursor: 33.0;ependymal cell: 21.3;oligodendrocyte: 84.3" "Group enriched" "Detected in some" 5 "Glioblastoma Multiforme (TCGA): 5.4;Liver Hepatocellular Carcinoma (TCGA): 1.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Lung - Respiratory ciliated cells, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" HPA077250 Enhanced NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 55: Lymphoma - Immune response" "Cluster 80: Oligodendrocytes - Myelination" "HPA077250: " "unprognostic (1.23e-1)" "unprognostic (1.71e-3)" "unprognostic (1.65e-2)" "potential prognostic favorable (3.27e-5)" PRR19 MGC70924 ENSG00000188368 "Proline rich 19" A6NJB7 19 42302098-42310814 "Predicted intracellular proteins" Meiosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 20.4" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 29.3;Early primary spermatocytes: 31.2;Early spermatids: 27.6;Late primary spermatocytes: 39.6;Late spermatids: 102.4" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA070350 Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Nuclear bodies,Mitotic chromosome,Mitochondria" Yes No "Cluster 43: Non-specific - Transcription & Translation" "Cluster 67: Testis - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 2 "Nucleoli, Nucleoli rim, Mitotic chromosome" "Nucleoplasm, Nuclear bodies, Mitochondria" "HPA070350: " "unprognostic (1.34e-2)" "unprognostic (1.34e-1)" "unprognostic (1.15e-2)" "unprognostic (1.98e-2)" "unprognostic (5.85e-2)" "unprognostic (1.31e-1)" "unprognostic (1.73e-1)" "unprognostic (1.77e-1)" "unprognostic (6.66e-3)" "unprognostic (5.96e-2)" "unprognostic (3.17e-2)" "validated prognostic unfavorable (1.46e-4)" "validated prognostic unfavorable (3.43e-5)" "unprognostic (9.61e-3)" "unprognostic (3.98e-3)" "unprognostic (1.00e-3)" "unprognostic (1.30e-1)" "unprognostic (3.75e-2)" "unprognostic (2.56e-3)" "unprognostic (1.03e-1)" "unprognostic (8.41e-2)" "unprognostic (1.70e-1)" "unprognostic (3.59e-2)" "unprognostic (1.32e-1)" "unprognostic (1.26e-1)" "unprognostic (1.03e-1)" "unprognostic (3.44e-1)" PRR20A "FLJ40296, PRR20" ENSG00000204919 "Proline rich 20A" P86496 13 57140918-57143939 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA059485 Uncertain NA NA "Cluster 32: Non-specific - Cell proliferation" 7 "HPA059485: " PRR20B ENSG00000204918 "Proline rich 20B" P86481 13 57147488-57150509 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA059485 Uncertain NA NA "Cluster 32: Non-specific - Cell proliferation" "HPA059485: " PRR20C ENSG00000229665 "Proline rich 20C" P86479 13 57140918-57157082 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA059485 Uncertain NA NA "Cluster 32: Non-specific - Cell proliferation" 20 "HPA059485: " PRR20D ENSG00000227151 "Proline rich 20D" P86480 13 57160632-57163653 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA059485 Uncertain NA NA "Cluster 32: Non-specific - Cell proliferation" 55 "HPA059485: " PRR20E ENSG00000234278 "Proline rich 20E" P86478 13 57167197-57170218 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA059485 Uncertain NA NA "Cluster 32: Non-specific - Cell proliferation" 6 "HPA059485: " PRR20G ENSG00000239620 "Proline rich 20G" P0DPQ3 3 127283783-127288046 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 91 "testis: 9.0" "Group enriched" "Detected in some" 12 "Differentiating spermatogonia: 59.0;Early primary spermatocytes: 81.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 3.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Spermatocytes" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 106: Spermatogonia - Spermatogonial differentiation" "unprognostic (6.71e-3)" "unprognostic (1.06e-1)" "unprognostic (1.84e-1)" "unprognostic (1.08e-1)" "unprognostic (1.59e-1)" PRR22 MGC24975 ENSG00000212123 "Proline rich 22" Q8IZ63 19 5782960-5784746 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "testis: 48.4" "Group enriched" "Detected in many" 15 "Early spermatids: 174.0;Late primary spermatocytes: 165.2;Late spermatids: 114.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" HPA044157 Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 34: Non-specific - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" Nucleoplasm "Vesicles, Cytosol" "HPA044157: " "unprognostic (6.17e-3)" "unprognostic (2.59e-1)" "unprognostic (1.54e-1)" "unprognostic (1.08e-2)" "unprognostic (3.18e-2)" "unprognostic (4.37e-1)" "unprognostic (2.32e-1)" "unprognostic (1.25e-1)" "unprognostic (3.03e-1)" "unprognostic (1.91e-1)" "unprognostic (8.60e-3)" "unprognostic (2.09e-1)" "unprognostic (9.51e-2)" "unprognostic (8.53e-2)" "unprognostic (2.67e-3)" "unprognostic (4.07e-2)" "unprognostic (2.96e-2)" "unprognostic (1.75e-1)" "unprognostic (1.89e-3)" "unprognostic (1.51e-3)" "unprognostic (8.31e-3)" "unprognostic (3.19e-1)" "unprognostic (3.90e-1)" "unprognostic (1.01e-1)" "potential prognostic favorable (8.34e-4)" "unprognostic (1.01e-1)" "unprognostic (2.55e-1)" "unprognostic (1.81e-1)" PRR23A ENSG00000206260 "Proline rich 23A" A6NEV1 3 139003962-139006268 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 14 "testis: 2.1" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 9.8;Early primary spermatocytes: 29.7;Early spermatids: 2.4;Late primary spermatocytes: 3.8;Oocytes: 18.4;Undifferentiated spermatogonia: 5.5" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Testicular Germ Cell Tumor (TCGA): 1.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Spermatocytes" HPA047473 Uncertain Approved "Nucleoplasm,Nuclear bodies,Microtubules,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes NA "Cluster 57: Testis - Spermatogenesis" "Cluster 48: Non-specific - Mixed function" "Cluster 3: Early primary spermatocytes - Early meiosis" "Nucleoplasm, Microtubules" "Nuclear bodies, Cytokinetic bridge, Mitotic spindle, Cytosol" "HPA047473: " "unprognostic (3.42e-1)" PRR23B FLJ46116 ENSG00000184814 "Proline rich 23B" Q6ZRT6 3 139019031-139020926 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 13 "testis: 1.2" "Group enriched" "Detected in some" 18 "Differentiating spermatogonia: 4.1;Early primary spermatocytes: 7.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Spermatocytes" HPA047473 Uncertain Uncertain "Nucleoplasm,Nuclear bodies,Microtubules,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes NA "Cluster 23: Testis - Spermatogenesis" "Cluster 3: Early primary spermatocytes - Early meiosis" 3 "Nucleoplasm, Microtubules" "Nuclear bodies, Cytokinetic bridge, Mitotic spindle, Cytosol" "HPA047473: " PRR23C FLJ46210 ENSG00000233701 "Proline rich 23C" Q6ZRP0 3 139042102-139044892 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Differentiating spermatogonia: 3.8;Early primary spermatocytes: 3.0;Early spermatids: 3.7;Late spermatids: 4.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.0" "Not detected" "Not detected" "Testis - Spermatocytes" HPA047473 Uncertain Approved "Nucleoplasm,Nuclear bodies,Microtubules,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes NA "Cluster 48: Non-specific - Mixed function" "Cluster 106: Spermatogonia - Spermatogonial differentiation" "Nucleoplasm, Microtubules" "Nuclear bodies, Cytokinetic bridge, Mitotic spindle, Cytosol" "HPA047473: " PRR23D1 ENSG00000255251 "Proline rich 23 domain containing 1" E9PI22 8 7539627-7542450 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 97 "epididymis: 175.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 53: Squamous epithelial cells - Keratinization" 1 PRR23D2 ENSG00000255378 "Proline rich 23 domain containing 2" P0DMB1 8 7778591-7781413 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 8 "testis: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 79: Testis - Spermatogenesis" PRR27 C4orf40 ENSG00000187533 "Proline rich 27" Q6MZM9 4 70133616-70176799 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 955 "salivary gland: 1039.5" "Group enriched" "Detected in some" 11 "Lacrimal acinar cells: 403.1;Salivary acinar cells: 956.6" "Cell type enhanced" "Detected in single" "thalamic excitatory: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "HPA036150, HPA036151" Enhanced "Secreted to digestive system" "No annotated function" NA NA "Cluster 82: Salivary gland - Secretion" "Cluster 34: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 1 "HPA036150: , HPA036151: " PRR29 "C17orf72, DKFZp761M2312, FLJ11724" ENSG00000224383 "Proline rich 29" P0C7W0 17 63998351-64004305 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "choroid plexus: 16.5;fallopian tube: 54.8" "Group enriched" "Detected in some" 6 "Endometrial ciliated cells: 71.3;Ependymal cells: 154.6;Epididymal efferent duct ciliated cells: 120.5;Fallopian tube ciliated cells: 186.4;Respiratory ciliated cells: 149.9" "Cell type enriched" "Detected in many" 11 "ependymal cell: 174.0" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 8.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 2.0" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "midbrain: 5.7" HPA051264 Uncertain Nucleoli NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 6: Leukemia - Signal transduction" "Cluster 34: Ciliated cells - Cilia assembly & function" Nucleoli "HPA051264: " "unprognostic (9.23e-2)" "unprognostic (4.41e-3)" "unprognostic (1.53e-1)" "potential prognostic unfavorable (1.97e-4)" "unprognostic (1.38e-2)" "unprognostic (4.32e-2)" "unprognostic (5.16e-3)" "unprognostic (3.89e-2)" "unprognostic (1.74e-1)" "unprognostic (3.51e-1)" "unprognostic (8.29e-3)" "unprognostic (3.20e-3)" "unprognostic (3.68e-1)" "unprognostic (2.52e-1)" "unprognostic (1.13e-2)" PRR3 "CAT56, Em:AB014077.1, Em:AB023052.2" ENSG00000204576 "Proline rich 3" P79522 6 30557280-30563723 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 14.3" "Cell type enhanced" "Detected in some" "Astrocytes: 18.4;Bergmann glia: 25.3;Brain excitatory neurons: 25.3;Brain inhibitory neurons: 23.0;Choroid plexus epithelial cells: 30.5;Distal convoluted tubule cells: 15.0;Ependymal cells: 20.3;Loop of henle epithelial cells: 12.7;Microglia: 20.1;Oligodendrocyte progenitor cells: 23.3;Oligodendrocytes: 19.9;Other brain neurons: 25.9;Papillary tip epithelial cells: 11.1;Podocytes: 13.4;Proximal tubule cells: 13.3;Renal collecting duct intercalated cells: 11.8;Renal collecting duct principal cells: 11.2;Renal connecting tubule cells: 12.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.2" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Neuroblastoma: 5.6" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064061 Approved Nucleoplasm,Cytosol NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 47: Leukemia - Hemostasis" "Cluster 98: Neurons - Neurotransmission & signaling" 96 Nucleoplasm Cytosol "HPA064061: " "unprognostic (1.46e-1)" "unprognostic (1.78e-1)" "unprognostic (4.57e-3)" "unprognostic (2.15e-2)" "unprognostic (1.36e-1)" "unprognostic (2.34e-3)" "unprognostic (1.72e-1)" "unprognostic (8.89e-2)" "unprognostic (4.23e-1)" PRR30 "C2orf53, MGC44505" ENSG00000186143 "Proline rich 30" Q53SZ7 2 27136848-27139410 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1243 "testis: 138.1" "Group enriched" "Detected in some" 4 "Early spermatids: 716.7;Late spermatids: 1334.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 3 PRR32 CXorf64 ENSG00000183631 "Proline rich 32" B1ATL7 X 126819729-126821786 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "tongue: 20.8" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Glioblastoma Multiforme (TCGA): 1.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Sarcoma: 1.2" "Group enriched" "Detected in many" 4 "basal ganglia: 3.5;hippocampal formation: 10.7;pons and medulla: 13.5;thalamus: 8.2" "Low region specificity" "Detected in single" HPA048386 Uncertain Approved "Nuclear speckles,Plasma membrane,Centrosome" NA NA "Cluster 41: Striated muscle - Muscle contraction" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 4 "Plasma membrane" "Nuclear speckles, Centrosome" "HPA048386: " "unprognostic (1.04e-2)" "unprognostic (2.94e-3)" PRR33 "C11orf89, LOC728008" ENSG00000283787 "Proline rich 33" 11 1888078-1891895 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "adrenal gland: 21.8;lymphoid tissue: 26.3;skeletal muscle: 33.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 6 "neutrophil: 1.4" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.4" "Group enriched" "Detected in some" 9 "Leukemia: 1.7;lymphoma: 4.3;Myeloma: 2.9" "Adipose subcutaneous - Adipose progenitor cells, Kidney - T-cells, Minor Salivary Gland - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 12: Non-specific - Vasculature" "Cluster 59: Leukemia - T-cell receptor" "unprognostic (1.95e-2)" "unprognostic (1.05e-1)" "unprognostic (3.28e-1)" "unprognostic (1.98e-1)" PRR35 C16orf11 ENSG00000161992 "Proline rich 35" P0CG20 16 560394-565529 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "brain: 137.2" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 17.9;Renal collecting duct intercalated cells: 4.0;Renal collecting duct principal cells: 15.8;Renal connecting tubule cells: 21.0;Retinal amacrine cells: 17.9;Undifferentiated spermatogonia: 5.2" "Group enriched" "Detected in some" 7 "cerebellar inhibitory: 26.3;upper rhombic lip: 42.8" "Cancer enhanced" "Detected in single" "Kidney Chromophobe (TCGA): 1.0" "Region enriched" "Detected in many" 21 "cerebellum: 96.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebellum: 4.5" "Not detected" "Not detected" HPA069297 Approved "Nucleoli,Cytokinetic bridge,Cytosol" Yes NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 65: Non-specific - Unknown function" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 58 Nucleoli "Cytokinetic bridge, Cytosol" "HPA069297: " "potential prognostic favorable (8.23e-4)" PRR36 ENSG00000183248 "Proline rich 36" Q9H6K5 19 7868719-7874390 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 46.0;pituitary gland: 27.8" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 10.6;Brain excitatory neurons: 13.5;Brain inhibitory neurons: 11.7;Breast hormone-responsive cells: 11.1;Corticotrophs: 11.7;Gonadotrophs: 22.2;Lactotrophs: 11.9;Oocytes: 18.4;Other brain neurons: 14.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 17.0" "Breast - Breast glandular cells, Colon - Colon enteroendocrine cells, Minor Salivary Gland - Minor salivary glandular cells, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062741 Uncertain Approved "Nucleoplasm,Nuclear speckles,Golgi apparatus" Yes No "Cluster 27: Cerebellum - Synaptic function" "Cluster 53: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 4 "Golgi apparatus" "Nucleoplasm, Nuclear speckles" "HPA062741: " "unprognostic (5.27e-3)" "unprognostic (2.66e-2)" "unprognostic (8.81e-2)" "unprognostic (1.46e-1)" "unprognostic (2.86e-1)" "unprognostic (2.11e-1)" "unprognostic (3.58e-1)" "unprognostic (2.15e-1)" "unprognostic (1.85e-2)" "unprognostic (4.39e-2)" "unprognostic (2.62e-1)" "unprognostic (1.15e-3)" "unprognostic (4.57e-2)" "unprognostic (4.67e-3)" "unprognostic (2.43e-1)" "unprognostic (1.88e-1)" "unprognostic (1.55e-2)" "unprognostic (3.94e-2)" "unprognostic (2.40e-3)" "unprognostic (2.45e-1)" "unprognostic (3.39e-1)" PRR4 "LPRP, PROL4" ENSG00000111215 "Proline rich 4" Q16378 12 10845849-10849475 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 48 "salivary gland: 6404.5" "Cell type enriched" "Detected in some" 4 "Lacrimal acinar cells: 1970.2" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 42.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 19 "skin cancer: 5.0" "Breast - Breast glandular cells (progenitors), Minor Salivary Gland - Minor salivary glandular cells, Skin - Eccrine sweat gland cells" HPA042133 Supported "Secreted to digestive system" "No annotated function" NA NA 2400000 "Cluster 82: Salivary gland - Secretion" "Cluster 69: Skin cancer - ECM organization" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 9 "HPA042133: " "unprognostic (3.36e-2)" "unprognostic (1.94e-1)" "unprognostic (1.57e-2)" "unprognostic (3.01e-1)" "unprognostic (4.74e-2)" "unprognostic (3.51e-2)" "unprognostic (4.01e-2)" "unprognostic (3.21e-1)" "unprognostic (3.28e-1)" "unprognostic (3.23e-1)" "unprognostic (6.07e-2)" "potential prognostic unfavorable (4.89e-4)" "unprognostic (2.07e-2)" "unprognostic (1.52e-1)" "unprognostic (9.83e-2)" PRR5 "FLJ20185k, PP610, Protor-1" ENSG00000186654 "Proline rich 5" P85299 22 44668547-44737681 "Predicted intracellular proteins" "Cell cycle" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 57.8;Astrocytes: 47.1;Choroid plexus epithelial cells: 88.7;Hofbauer cells: 37.1;Lactotrophs: 26.3;Mast cells: 32.6;Microglia: 31.3;NK-cells: 27.1;Pituicytes/FSCs: 44.9;Proximal tubule cells: 38.5;Somatotrophs: 43.7;Thyrotrophs: 36.7" "Cell type enhanced" "Detected in many" "leukocyte: 79.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "monocytes: 19.2;T-cells: 28.6" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054072 Approved NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 12 "HPA054072: " "unprognostic (1.43e-1)" "unprognostic (6.48e-2)" "unprognostic (1.10e-1)" "unprognostic (2.29e-2)" "unprognostic (9.68e-2)" "unprognostic (7.79e-2)" "unprognostic (9.59e-2)" "unprognostic (7.79e-2)" "unprognostic (3.58e-2)" "unprognostic (1.57e-1)" "unprognostic (3.25e-2)" "unprognostic (3.51e-2)" "unprognostic (2.01e-1)" "unprognostic (1.14e-1)" "unprognostic (3.57e-3)" "unprognostic (4.23e-2)" "unprognostic (4.45e-1)" "unprognostic (3.24e-1)" "unprognostic (3.60e-3)" "unprognostic (2.17e-2)" "unprognostic (1.92e-1)" "unprognostic (8.38e-2)" "unprognostic (1.32e-1)" "unprognostic (1.18e-1)" "unprognostic (2.06e-1)" "unprognostic (8.05e-3)" "unprognostic (9.18e-2)" "potential prognostic favorable (3.44e-4)" "unprognostic (2.18e-1)" "unprognostic (1.96e-2)" "unprognostic (6.60e-3)" PRR5-ARHGAP8 ENSG00000248405 "PRR5-ARHGAP8 readthrough" 22 44702233-44862706 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Adipocytes: 12.5;Epididymal clear cells: 14.3;Epididymal efferent duct absorptive cells: 13.5;Innate lymphoid cells: 18.8;Retinal ganglion cells: 15.5;Thymocytes: 11.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 1 "unprognostic (8.58e-2)" "unprognostic (6.73e-3)" "unprognostic (3.32e-3)" "unprognostic (4.54e-2)" "unprognostic (3.48e-2)" "unprognostic (1.38e-1)" "unprognostic (4.11e-1)" "unprognostic (1.26e-1)" "unprognostic (2.60e-1)" "unprognostic (4.56e-1)" "unprognostic (6.36e-2)" "unprognostic (2.66e-2)" "unprognostic (2.51e-1)" "unprognostic (1.25e-1)" "unprognostic (1.01e-1)" "unprognostic (1.13e-1)" "unprognostic (6.98e-2)" "unprognostic (1.91e-1)" "unprognostic (2.18e-2)" "unprognostic (1.09e-1)" PRR5L "FLJ14213, PROTOR-2" ENSG00000135362 "Proline rich 5 like" Q6MZQ0 11 36296288-36465204 "Predicted intracellular proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.4;intestine: 32.5;lymphoid tissue: 34.3" "Cell type enhanced" "Detected in many" "Colonocytes: 88.3;Late spermatids: 76.9;Lymphatic endothelial cells: 80.2;NK-cells: 103.8;Oligodendrocytes: 340.5;Salivary duct cells: 109.3;Salivary ionocytes: 115.8" "Cell type enhanced" "Detected in many" "leukocyte: 160.0;oligodendrocyte: 546.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 46.9" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070174 Approved "Cytokinetic bridge,Cytosol" Yes No "Cluster 45: Eosinophils - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 30: White matter - Myelination" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 80: Oligodendrocytes - Myelination" 17 "Cytokinetic bridge, Cytosol" "HPA070174: " "unprognostic (3.95e-1)" "unprognostic (1.45e-1)" "unprognostic (2.15e-1)" "unprognostic (5.83e-2)" "unprognostic (2.13e-1)" "unprognostic (1.52e-2)" "unprognostic (1.06e-1)" "unprognostic (2.19e-1)" "unprognostic (1.16e-1)" "unprognostic (1.16e-2)" "unprognostic (5.05e-3)" "unprognostic (1.99e-1)" "potential prognostic unfavorable (4.18e-4)" "unprognostic (1.19e-1)" "unprognostic (5.21e-2)" "unprognostic (1.73e-1)" "unprognostic (1.95e-2)" "unprognostic (8.69e-2)" "unprognostic (8.65e-2)" "unprognostic (3.87e-2)" "unprognostic (3.90e-1)" "unprognostic (1.56e-2)" "unprognostic (1.21e-1)" "unprognostic (1.60e-1)" "potential prognostic favorable (2.33e-4)" "unprognostic (2.74e-2)" "unprognostic (7.84e-2)" "unprognostic (1.07e-2)" "unprognostic (1.84e-1)" "unprognostic (4.94e-2)" "unprognostic (2.26e-1)" PRR7 MGC10772 ENSG00000131188 "Proline rich 7, synaptic" Q8TB68 5 177446445-177456286 "Predicted intracellular proteins, Transporters" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 31.9" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 45.3;Epididymal efferent duct ciliated cells: 45.7;Fallopian tube ciliated cells: 67.7;Megakaryocytes: 123.6;Platelets: 60.6;Respiratory ciliated cells: 63.9;Suprabasal keratinocytes: 46.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA046636 Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 78: Brain - Neuronal signaling" "Cluster 29: Forebrain - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 3 "Nucleoplasm, Plasma membrane, Cytosol" "HPA046636: " "unprognostic (1.60e-1)" "unprognostic (2.25e-2)" "unprognostic (3.21e-2)" "unprognostic (6.29e-3)" "unprognostic (1.16e-1)" "unprognostic (2.18e-2)" "unprognostic (1.68e-2)" "unprognostic (1.74e-1)" "unprognostic (4.92e-2)" "unprognostic (1.25e-2)" "unprognostic (6.31e-3)" "unprognostic (5.47e-3)" "unprognostic (5.97e-2)" "validated prognostic unfavorable (3.63e-4)" "validated prognostic unfavorable (9.43e-4)" "unprognostic (3.61e-2)" "unprognostic (8.78e-2)" "unprognostic (4.54e-2)" "unprognostic (4.93e-2)" "unprognostic (4.71e-2)" "unprognostic (1.09e-2)" "unprognostic (1.02e-2)" "unprognostic (1.13e-1)" "unprognostic (7.74e-3)" "unprognostic (3.29e-2)" "unprognostic (3.74e-2)" "unprognostic (2.33e-2)" "unprognostic (2.52e-2)" "unprognostic (1.09e-1)" PRR9 ENSG00000203783 "Proline rich 9" Q5T870 1 153217584-153219310 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "skin 1: 54.2" "Group enriched" "Detected in some" 4 "Late spermatids: 18.1;Syncytiotrophoblasts: 23.9" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 12.4;Head and Neck Squamous Cell Carcinoma (TCGA): 17.7" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 10.4;testis cancer: 16.4" "Skin - Hair cortex cells, Skin - Inner root sheath cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA027714 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 47: Endothelial cells - Vasculature" "Cluster 32: Non-specific - Cell proliferation" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" Cytosol "Nucleoplasm, Vesicles" "HPA027714: " "unprognostic (1.69e-2)" "unprognostic (2.72e-1)" "unprognostic (4.10e-1)" "unprognostic (3.48e-1)" "unprognostic (2.89e-1)" "unprognostic (1.65e-1)" "unprognostic (5.20e-3)" "unprognostic (4.03e-1)" "unprognostic (7.31e-2)" "unprognostic (3.27e-1)" PRRC1 FLJ32875 ENSG00000164244 "Proline rich coiled-coil 1" Q96M27 5 127517640-127555085 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039212 Supported Approved Vesicles NA NA 64000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 70: Non-specific - Protein processing" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 63: Non-specific - Protein processing" "Cluster 8: Non-specific - Secretory pathway" 9 Vesicles "HPA039212: " "unprognostic (1.10e-1)" "unprognostic (1.18e-3)" "unprognostic (2.07e-1)" "unprognostic (4.69e-2)" "unprognostic (1.87e-1)" "unprognostic (6.42e-2)" "unprognostic (1.94e-1)" "unprognostic (3.28e-1)" "unprognostic (2.03e-1)" "potential prognostic unfavorable (1.32e-4)" "potential prognostic favorable (7.05e-6)" "unprognostic (1.73e-1)" "unprognostic (3.17e-2)" "unprognostic (4.96e-2)" "unprognostic (1.57e-1)" "unprognostic (3.75e-2)" "unprognostic (1.58e-2)" "unprognostic (1.98e-1)" "unprognostic (1.40e-2)" "unprognostic (2.22e-2)" "potential prognostic unfavorable (3.22e-4)" "potential prognostic unfavorable (2.56e-4)" "unprognostic (5.31e-2)" "unprognostic (2.08e-1)" "unprognostic (1.57e-1)" "unprognostic (4.07e-3)" "unprognostic (2.36e-2)" "unprognostic (1.65e-1)" "unprognostic (2.98e-1)" "unprognostic (3.55e-3)" "unprognostic (2.62e-1)" PRRC2A "BAT2, D6S51E, G2" ENSG00000204469 "Proline rich coiled-coil 2A" P48634 6 31620715-31637771 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 53.9;Podocytes: 52.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026383, HPA046791, HPA066501" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 64: Non-specific - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 102: Non-specific - Mixed function" 37 Cytosol "Nucleoplasm, Plasma membrane" "CAB026383: , HPA046791: , HPA066501: " "unprognostic (1.38e-1)" "unprognostic (8.05e-2)" "unprognostic (1.03e-2)" "unprognostic (7.62e-2)" "unprognostic (2.90e-1)" "unprognostic (5.42e-3)" "unprognostic (3.01e-1)" "unprognostic (2.66e-2)" "unprognostic (1.33e-1)" "unprognostic (2.79e-1)" "unprognostic (1.04e-1)" "unprognostic (6.25e-3)" "unprognostic (2.25e-1)" "potential prognostic unfavorable (7.08e-4)" "unprognostic (1.00e-1)" "unprognostic (2.67e-1)" "unprognostic (1.76e-1)" "unprognostic (3.36e-1)" "unprognostic (2.08e-3)" "unprognostic (1.97e-1)" "unprognostic (2.04e-1)" "unprognostic (9.41e-3)" "unprognostic (2.83e-3)" "unprognostic (5.69e-2)" "unprognostic (1.85e-1)" "unprognostic (4.36e-1)" "unprognostic (4.73e-1)" "unprognostic (5.95e-2)" "unprognostic (2.17e-2)" "unprognostic (1.06e-1)" PRRC2B "BAT2L, BAT2L1, KIAA0515, LQFBS-1, MGC10526" ENSG00000288701 "Proline rich coiled-coil 2B" Q5JSZ5 9 131373636-131500197 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021022, HPA064301" Approved Approved "Nuclear bodies,Cytosol" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 65: Brain - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 17: Non-specific - RNA processing" 22 Cytosol "Nuclear bodies" "HPA021022: , HPA064301: " PRRC2C "BAT2D1, BAT2L2, KIAA1096, XTP2" ENSG00000117523 "Proline rich coiled-coil 2C" Q9Y520 1 171485530-171593511 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025766, HPA028659" Approved Enhanced Cytosol NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 49: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 45: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 23 Cytosol "HPA025766: , HPA028659: " "unprognostic (3.05e-1)" "unprognostic (9.94e-2)" "potential prognostic unfavorable (4.53e-4)" "unprognostic (1.08e-2)" "unprognostic (1.73e-1)" "unprognostic (2.66e-2)" "unprognostic (1.56e-1)" "unprognostic (1.56e-1)" "unprognostic (2.33e-2)" "unprognostic (3.75e-2)" "unprognostic (7.24e-2)" "potential prognostic unfavorable (7.10e-4)" "unprognostic (1.97e-2)" "unprognostic (1.90e-1)" "unprognostic (3.82e-2)" "unprognostic (1.01e-3)" "unprognostic (1.31e-1)" "unprognostic (1.44e-1)" "unprognostic (1.60e-1)" "unprognostic (2.03e-1)" "unprognostic (1.83e-2)" "unprognostic (9.93e-3)" "unprognostic (1.08e-2)" "unprognostic (1.69e-1)" "unprognostic (6.88e-2)" "unprognostic (4.68e-3)" "unprognostic (1.68e-1)" "unprognostic (3.44e-1)" "unprognostic (2.73e-1)" "unprognostic (1.00e-1)" PRRG1 PRGP1 ENSG00000130962 "Proline rich and Gla domain 1" O14668 X 37349309-37457292 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 40.4" "Cell type enriched" "Detected in many" 5 "Oligodendrocytes: 234.5" "Cell type enhanced" "Detected in all" "endothelial cell: 238.9;oligodendrocyte: 339.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells, Colon - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078129 Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 15: Kidney cancer - Membrane components" "Cluster 104: Brain endothelial cells - Blood brain barrier" 7 "Vesicles, Plasma membrane" Nucleoplasm "HPA078129: " "unprognostic (2.30e-1)" "unprognostic (1.47e-1)" "unprognostic (1.37e-1)" "unprognostic (1.01e-2)" "unprognostic (8.22e-2)" "unprognostic (4.68e-2)" "unprognostic (1.05e-1)" "unprognostic (2.89e-2)" "unprognostic (1.21e-2)" "unprognostic (1.62e-1)" "potential prognostic favorable (9.27e-7)" "unprognostic (1.29e-1)" "unprognostic (1.15e-2)" "unprognostic (4.77e-3)" "unprognostic (4.88e-2)" "unprognostic (1.57e-3)" "unprognostic (1.16e-2)" "unprognostic (9.68e-3)" "potential prognostic unfavorable (6.27e-4)" "unprognostic (5.74e-3)" "potential prognostic unfavorable (5.31e-6)" "potential prognostic unfavorable (1.81e-4)" "unprognostic (4.12e-2)" "unprognostic (5.58e-2)" "unprognostic (5.89e-2)" "unprognostic (1.17e-1)" "unprognostic (1.84e-1)" "unprognostic (6.60e-2)" "unprognostic (2.33e-1)" "unprognostic (6.31e-2)" "unprognostic (1.30e-2)" PRRG2 PRGP2 ENSG00000126460 "Proline rich and Gla domain 2" O14669 19 49580646-49591004 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 26.6" "Cell type enhanced" "Detected in many" "Colonocytes: 42.2;Enterocytes: 45.7;Esophageal apical cells: 84.8;Esophageal suprabasal cells: 40.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.2" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010702 Approved Approved Nucleoplasm,Nucleoli,Cytosol No NA "Cluster 33: Thyroid gland - Tissue development" "Cluster 25: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 4 "Nucleoplasm, Nucleoli" Cytosol "HPA010702: " "unprognostic (1.77e-2)" "unprognostic (1.93e-1)" "unprognostic (1.45e-1)" "unprognostic (3.19e-1)" "unprognostic (1.03e-2)" "unprognostic (1.22e-1)" "unprognostic (1.57e-1)" "unprognostic (1.17e-1)" "unprognostic (3.04e-1)" "unprognostic (2.56e-1)" "potential prognostic favorable (3.75e-4)" "unprognostic (8.13e-3)" "potential prognostic favorable (3.28e-4)" "unprognostic (4.01e-1)" "unprognostic (8.65e-2)" "unprognostic (9.46e-2)" "unprognostic (4.24e-1)" "unprognostic (1.35e-1)" "unprognostic (1.41e-1)" "unprognostic (1.83e-1)" "unprognostic (3.87e-2)" "unprognostic (8.95e-2)" "unprognostic (2.85e-1)" "unprognostic (2.14e-1)" "unprognostic (4.38e-1)" "potential prognostic unfavorable (6.03e-4)" "unprognostic (3.79e-1)" "unprognostic (2.04e-1)" "unprognostic (1.06e-1)" "unprognostic (8.76e-2)" "unprognostic (9.75e-2)" PRRG3 TMG3 ENSG00000130032 "Proline rich and Gla domain 3" Q9BZD7 X 151694607-151705924 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.0;epididymis: 7.0" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 13.3;Brain inhibitory neurons: 13.9;Epididymal principal cells: 5.4;Fibro-adipogenic progenitors: 8.7;Fibroblasts: 8.5;Medullary thymic epithelial cells: 12.0;Other brain neurons: 17.8;Salivary basal cells: 4.9;Schwann cells: 8.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 4 "testis cancer: 2.4;thyroid cancer: 1.5" "Adipose subcutaneous - Adipose progenitor cells, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA060566 Uncertain NA NA "Cluster 24: Non-specific - Transcription" "Cluster 78: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 98: Neurons - Neurotransmission & signaling" "HPA060566: " "unprognostic (7.04e-2)" "unprognostic (8.80e-2)" "unprognostic (1.23e-1)" "potential prognostic unfavorable (1.43e-4)" "unprognostic (1.39e-2)" "unprognostic (4.00e-2)" "unprognostic (1.32e-3)" "unprognostic (9.89e-2)" "unprognostic (8.12e-2)" "unprognostic (1.21e-1)" "unprognostic (5.40e-2)" "unprognostic (9.13e-2)" PRRG4 TMG4 ENSG00000135378 "Proline rich and Gla domain 4" Q9BZD6 11 32829927-32858120 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 424.3;Esophageal basal cells: 195.5;Esophageal suprabasal cells: 334.7;Ocular epithelial cells: 379.3;Suprabasal keratinocytes: 214.1;Urothelial cells: 244.7" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 29.2;choroid plexus epithelial cell: 11.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "neutrophil: 11.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 11.9" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Liver - Hepatocytes, Lung - Alveolar cells type 1, Prostate - Prostate basal glandular cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA009040, HPA024566" Uncertain Uncertain "Golgi apparatus" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 20 "Golgi apparatus" "HPA009040: , HPA024566: " "unprognostic (4.42e-2)" "unprognostic (3.06e-1)" "unprognostic (1.28e-1)" "unprognostic (8.56e-2)" "unprognostic (3.89e-1)" "unprognostic (1.62e-1)" "unprognostic (1.26e-1)" "unprognostic (1.33e-1)" "unprognostic (1.57e-1)" "unprognostic (2.60e-2)" "potential prognostic favorable (3.70e-6)" "unprognostic (1.48e-3)" "unprognostic (3.33e-1)" "unprognostic (4.11e-2)" "unprognostic (7.19e-2)" "unprognostic (7.17e-2)" "potential prognostic unfavorable (3.68e-4)" "unprognostic (2.26e-1)" "unprognostic (3.82e-1)" "unprognostic (1.48e-1)" "unprognostic (5.91e-2)" "potential prognostic unfavorable (1.96e-4)" "unprognostic (8.53e-3)" "unprognostic (3.22e-1)" "unprognostic (9.82e-3)" "unprognostic (4.28e-2)" "unprognostic (2.44e-1)" "unprognostic (1.44e-2)" "unprognostic (1.27e-1)" "unprognostic (4.89e-1)" "unprognostic (1.40e-1)" PRRT1 "C6orf31, DSPD1, IFITMD7, NG5" ENSG00000204314 "Proline rich transmembrane protein 1" Q99946 6 32148359-32153083 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 67.2" "Cell type enhanced" "Detected in some" "Astrocytes: 7.4;Bergmann glia: 5.5;Brain excitatory neurons: 27.4;Brain inhibitory neurons: 22.6;Ependymal cells: 8.4;Oligodendrocyte progenitor cells: 9.2;Oligodendrocytes: 9.7;Other brain neurons: 20.7" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in single" "Glioblastoma Multiforme (TCGA): 1.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055149, HPA059099" Enhanced NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 51: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 98: Neurons - Neurotransmission & signaling" "HPA055149: , HPA059099: " "unprognostic (4.11e-1)" "unprognostic (3.45e-1)" "unprognostic (1.37e-1)" "unprognostic (1.73e-2)" "unprognostic (1.38e-1)" "unprognostic (1.81e-1)" PRRT1B "DSPD2, IFITMD8" ENSG00000283526 "Proline rich transmembrane protein 1B" A0A1B0GWB2 9 131545523-131559815 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 7.0;lung: 5.1;pancreas: 4.5" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 8.4;Epicardial cells: 6.8;Epididymal efferent duct ciliated cells: 5.0;Fallopian tube ciliated cells: 21.0;Gastric chief cells: 5.5;Goblet cells: 5.0;Neuroendocrine cells: 8.2;Pancreatic islet cells: 8.9;Parietal cells: 8.8;Pituitary stem cells: 5.3;Prostatic glandular cells: 4.8;Respiratory ciliated cells: 16.8" "Cell type enhanced" "Detected in single" "committed oligodendrocyte precursor: 1.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 3.8;liver cancer: 3.6;prostate cancer: 9.3" "Liver - Hepatocytes, Lung - Alveolar cells type 1, Prostate - Prostate glandular cells, Stomach - Chief cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" NA NA "Cluster 60: Stomach - Digestion" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" "unprognostic (1.95e-2)" "potential prognostic favorable (3.71e-4)" "unprognostic (2.21e-1)" "unprognostic (5.15e-2)" "unprognostic (1.81e-2)" "potential prognostic favorable (2.66e-4)" "unprognostic (3.82e-2)" "unprognostic (4.31e-2)" "unprognostic (1.58e-1)" "unprognostic (1.88e-1)" "unprognostic (7.73e-2)" "unprognostic (2.59e-1)" PRRT2 "DKFZp547J199, DSPB3, DYT10, EKD1, FICCA, FLJ25513, ICCA, IFITMD1, PKC" ENSG00000167371 "Proline rich transmembrane protein 2" Q7Z6L0 16 29811382-29815892 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant, Dystonia, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 305.2" "Cell type enhanced" "Detected in some" "Astrocytes: 55.4;Bergmann glia: 63.6;Brain excitatory neurons: 57.6;Brain inhibitory neurons: 40.5;Ependymal cells: 72.2;Late spermatids: 11.9;Oligodendrocyte progenitor cells: 16.4;Other brain neurons: 28.7" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 14.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "NK-cell: 3.3" "Lineage enriched" "Detected in single" 8 "NK-cells: 3.3" "Cancer enhanced" "Detected in many" "Neuroblastoma: 37.5" "Colon - Enteric glia cells, Kidney - Fibroblasts, Minor Salivary Gland - Fibroblasts, Pituitary gland - Lactotropes, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014447, HPA019203, HPA048045" Enhanced Supported "Plasma membrane" NA NA "Cluster 64: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 6 "Plasma membrane" "HPA014447: , HPA019203: , HPA048045: " "unprognostic (3.31e-1)" "unprognostic (8.65e-2)" "unprognostic (3.15e-1)" "unprognostic (5.15e-2)" "unprognostic (5.47e-3)" "unprognostic (8.32e-2)" "unprognostic (4.69e-2)" "unprognostic (9.89e-2)" "potential prognostic unfavorable (1.81e-4)" "unprognostic (2.07e-1)" "unprognostic (2.37e-2)" "unprognostic (4.61e-2)" "unprognostic (3.75e-1)" "unprognostic (9.55e-2)" "unprognostic (1.17e-1)" "unprognostic (6.05e-2)" "unprognostic (2.69e-1)" "potential prognostic favorable (7.59e-4)" "unprognostic (2.43e-2)" "unprognostic (2.83e-2)" "unprognostic (2.05e-2)" "unprognostic (1.70e-1)" "unprognostic (2.00e-1)" "unprognostic (2.49e-1)" "unprognostic (3.03e-2)" "unprognostic (1.73e-1)" "unprognostic (4.86e-2)" "unprognostic (6.45e-2)" PRRT3 FLJ33674 ENSG00000163704 "Proline rich transmembrane protein 3" Q5FWE3 3 9939450-9952408 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 13.9;choroid plexus: 7.0;fallopian tube: 7.1;parathyroid gland: 14.3;pituitary gland: 10.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 43.4;Corticotrophs: 28.9;Epicardial cells: 34.1;Fallopian tube ciliated cells: 29.2;Respiratory ciliated cells: 39.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Minor Salivary Gland - Minor salivary glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035127, HPA035128, HPA069859" Enhanced Approved "Nucleoplasm,Plasma membrane" "Intracellular and membrane" "No annotated function" NA NA 53000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 73: Brain - Neuronal signaling" "Cluster 37: Neurons - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "Plasma membrane" Nucleoplasm "HPA035127: , HPA035128: , HPA069859: " "unprognostic (9.96e-2)" "unprognostic (1.02e-1)" "unprognostic (2.20e-1)" "unprognostic (2.96e-2)" "unprognostic (5.09e-2)" "unprognostic (5.90e-2)" "unprognostic (1.99e-1)" "unprognostic (3.45e-1)" "unprognostic (7.69e-2)" "potential prognostic favorable (3.80e-4)" "potential prognostic favorable (5.33e-4)" "unprognostic (1.46e-3)" "unprognostic (9.83e-2)" "unprognostic (4.82e-2)" "unprognostic (8.43e-2)" "unprognostic (9.34e-2)" "unprognostic (1.08e-2)" "unprognostic (3.87e-1)" "unprognostic (9.65e-2)" "unprognostic (5.73e-2)" "unprognostic (5.33e-3)" "unprognostic (6.91e-2)" "unprognostic (2.89e-2)" "unprognostic (2.29e-1)" "unprognostic (2.52e-1)" PRRT4 ENSG00000224940 "Proline rich transmembrane protein 4" C9JH25 7 128350325-128361690 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adipose tissue: 15.6;bone marrow: 54.5" "Group enriched" "Detected in some" 4 "Adipocytes: 20.5;Adrenal medulla cells: 21.3;Brain inhibitory neurons: 9.4;Neutrophil progenitors: 22.3;Other brain neurons: 8.0;Retinal amacrine cells: 31.4;Retinal horizontal cells: 10.0" "Cell type enhanced" "Detected in many" "LAMP5-LHX6 and Chandelier: 14.7;MGE interneuron: 17.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Bone cancer: 27.0;Neuroblastoma: 70.2" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal medulla cells, Breast - Adipocytes (Breast), Spleen - Neutrophils_1, Stomach - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA046373, HPA052681" Uncertain Approved "Nucleoplasm,Peroxisomes,Plasma membrane" "Intracellular and membrane" "No annotated function" NA NA "Cluster 15: Bone marrow - Innate immune response" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 37: Neutrophil progenitors - Granulopoiesis" Nucleoplasm "Peroxisomes, Plasma membrane" "HPA046373: , HPA052681: " "unprognostic (4.64e-2)" "unprognostic (3.67e-2)" "unprognostic (2.50e-3)" "unprognostic (3.89e-1)" "unprognostic (8.04e-2)" "unprognostic (5.53e-2)" "unprognostic (1.73e-2)" "unprognostic (1.89e-1)" "unprognostic (1.17e-2)" PRRX1 "PHOX1, PMX1" ENSG00000116132 "Paired related homeobox 1" P54821 1 170662728-170739421 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 224.5;Bergmann glia: 285.9;Decidual stromal cells: 162.9;Early spermatids: 423.4;Endometrial stromal cells: 241.2;Fibro-adipogenic progenitors: 604.5;Fibroblasts: 399.8;Late spermatids: 486.3;Leydig cells: 461.2;Myonuclei: 448.6;Oligodendrocyte progenitor cells: 446.9;Pericytes: 349.9;Pituicytes/FSCs: 218.3;Smooth muscle cells: 187.4;Thymic myoid cells: 269.2;Vascular smooth muscle cells: 183.8" "Group enriched" "Detected in many" 5 "astrocyte: 313.6;Bergmann glia: 285.8;committed oligodendrocyte precursor: 238.3;fibroblast: 764.3;oligodendrocyte precursor cell: 546.8;pericyte: 284.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 53.8;Rhabdoid: 68.7" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051084, HPA063566" Uncertain Supported Nucleoplasm NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 19: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 2 Nucleoplasm "HPA051084: , HPA063566: " "unprognostic (1.02e-1)" "unprognostic (1.51e-1)" "unprognostic (2.06e-1)" "unprognostic (1.33e-1)" "unprognostic (3.69e-3)" "unprognostic (2.62e-1)" "unprognostic (3.26e-1)" "unprognostic (1.97e-1)" "unprognostic (3.01e-2)" "unprognostic (7.27e-2)" "unprognostic (8.60e-3)" "potential prognostic favorable (1.91e-4)" "potential prognostic unfavorable (7.68e-9)" "unprognostic (1.40e-2)" "unprognostic (2.20e-1)" "unprognostic (4.99e-2)" "unprognostic (6.08e-2)" "unprognostic (3.77e-2)" "unprognostic (1.92e-1)" "unprognostic (3.74e-2)" "potential prognostic unfavorable (2.68e-5)" "unprognostic (2.06e-2)" "unprognostic (3.05e-1)" "unprognostic (3.92e-1)" "unprognostic (3.95e-2)" "unprognostic (3.11e-3)" "unprognostic (1.27e-3)" "unprognostic (1.38e-3)" "unprognostic (6.03e-2)" "unprognostic (3.77e-3)" "unprognostic (1.87e-1)" PRRX2 "PMX2, PRX2" ENSG00000167157 "Paired related homeobox 2" Q99811 9 129665647-129722674 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 52.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 29.2;Breast myoepithelial cells: 21.5;Early spermatids: 91.2;Endometrial secretory cells: 72.6;Fibro-adipogenic progenitors: 33.2;Fibroblasts: 76.9;Late primary spermatocytes: 45.3;Pericytes: 37.6;Suprabasal keratinocytes: 21.2;Undifferentiated spermatogonia: 37.5;Vascular smooth muscle cells: 38.7" "Group enriched" "Detected in some" 9 "fibroblast: 7.2;oligodendrocyte precursor cell: 7.9;vascular associated smooth muscle cell: 3.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 19.0" "Adipose subcutaneous - Adipose progenitor cells, Minor Salivary Gland - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA006607, HPA026808" Approved Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" Nucleoplasm "Nuclear bodies" "HPA006607: , HPA026808: " "unprognostic (1.12e-1)" "unprognostic (2.94e-3)" "unprognostic (2.60e-1)" "unprognostic (2.32e-1)" "unprognostic (7.55e-3)" "unprognostic (1.43e-1)" "unprognostic (6.43e-2)" "unprognostic (2.06e-1)" "unprognostic (2.49e-3)" "unprognostic (1.42e-1)" "potential prognostic unfavorable (7.99e-4)" "unprognostic (1.81e-2)" "unprognostic (1.73e-1)" "unprognostic (2.91e-2)" "unprognostic (2.43e-2)" "unprognostic (1.37e-1)" "unprognostic (5.23e-2)" "unprognostic (2.26e-2)" "unprognostic (1.29e-1)" "unprognostic (5.09e-2)" "unprognostic (4.75e-3)" "potential prognostic unfavorable (9.20e-4)" "unprognostic (8.30e-2)" "unprognostic (2.46e-1)" "unprognostic (1.29e-2)" "unprognostic (8.55e-3)" PRSS1 TRY1 ENSG00000204983 "Serine protease 1" P07477 7 142749468-142753072 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4164 "pancreas: 319717.0" "Cell type enriched" "Detected in some" 543 "Pancreatic acinar cells: 114814.9" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 110 "Pancreatic Adenocarcinoma (TCGA): 3015.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 25.9" "Pancreas - Exocrine glandular cells" "CAB025487, CAB025538, HPA062452, HPA063471" Enhanced Approved "Endoplasmic reticulum,Vesicles" "Secreted to digestive system" Enzyme NA NA 1000000000 "Cluster 8: Pancreas - Proteolysis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 5: Pancreatic acinar cells - Pancreatic exocrine secretion" 2 Vesicles "Endoplasmic reticulum" "CAB025487: , CAB025538: , HPA062452: , HPA063471: " "unprognostic (9.19e-2)" "unprognostic (1.00e-1)" "unprognostic (3.58e-1)" "unprognostic (4.91e-2)" "unprognostic (1.18e-1)" "unprognostic (5.93e-2)" "unprognostic (4.50e-2)" "unprognostic (1.59e-1)" "unprognostic (2.71e-1)" "unprognostic (2.33e-2)" "unprognostic (8.60e-3)" "unprognostic (2.08e-2)" "unprognostic (1.48e-1)" "unprognostic (1.08e-1)" "unprognostic (2.55e-2)" "unprognostic (2.26e-1)" "unprognostic (1.40e-3)" PRSS12 "BSSP-3, MRT1" ENSG00000164099 "Serine protease 12" P56730 4 118280038-118353003 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 24.2" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 141.4;Colonocytes: 76.5;Cytotrophoblasts: 80.0;Endometrial ciliated cells: 67.5;Fallopian tube ciliated cells: 76.4;Foveolar cells: 173.7;Mast cells: 69.0;Migrating cytotrophoblasts: 101.7;Respiratory ciliated cells: 304.1;Transitional alveolar cells: 68.4" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 133.2;hippocampal CA4: 118.5;midbrain-derived inhibitory: 249.3" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 5 "choroid plexus: 32.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 86.9" "Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA035054 Uncertain "Secreted - unknown location" Enzyme NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 68: Foveolar cells - Mucosal defense" 2 "HPA035054: " "unprognostic (1.76e-1)" "unprognostic (2.13e-2)" "unprognostic (9.47e-3)" "unprognostic (1.50e-2)" "unprognostic (1.45e-1)" "unprognostic (4.19e-2)" "potential prognostic favorable (8.65e-4)" "unprognostic (3.25e-2)" "potential prognostic favorable (3.90e-4)" "unprognostic (1.02e-1)" "unprognostic (1.51e-1)" "unprognostic (1.68e-1)" "unprognostic (6.56e-3)" "unprognostic (4.44e-3)" "unprognostic (1.30e-1)" "unprognostic (6.89e-2)" "unprognostic (3.52e-1)" "unprognostic (6.61e-2)" "unprognostic (6.00e-2)" "unprognostic (4.07e-3)" "unprognostic (2.72e-1)" "unprognostic (2.83e-1)" "unprognostic (1.72e-2)" "unprognostic (2.36e-1)" "unprognostic (3.58e-2)" PRSS16 TSSP ENSG00000112812 "Serine protease 16" Q9NQE7 6 27247701-27256624 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 57 "lymphoid tissue: 770.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 49.0;Esophageal apical cells: 25.3;Extravillous trophoblasts: 30.7;Foveolar cells: 30.4;Gastric chief cells: 41.5;Gastric progenitor cells: 33.3;Migrating cytotrophoblasts: 39.2;Mucous neck cells: 25.9;Parietal cells: 30.1;Syncytiotrophoblasts: 34.6" "Cell type enhanced" "Detected in single" "choroid plexus epithelial cell: 3.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "memory B-cell: 2.1" "Lineage enhanced" "Detected in single" "B-cells: 2.1" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted in other tissues" Enzyme NA NA "Cluster 24: Non-specific - Transcription" "Cluster 80: Thymus - Adaptive immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 63: Cytotrophoblasts - Basic cellular functions" "unprognostic (1.54e-2)" "unprognostic (7.30e-2)" "unprognostic (2.32e-1)" "unprognostic (1.79e-2)" "unprognostic (2.28e-2)" "unprognostic (6.63e-3)" "unprognostic (5.77e-2)" "unprognostic (1.81e-1)" "unprognostic (2.38e-2)" "unprognostic (5.04e-2)" "unprognostic (2.69e-2)" "unprognostic (1.47e-1)" "unprognostic (5.90e-2)" "unprognostic (3.56e-2)" "unprognostic (2.18e-2)" "unprognostic (1.11e-1)" "potential prognostic favorable (3.24e-4)" "unprognostic (1.13e-1)" "unprognostic (3.34e-3)" "unprognostic (2.18e-1)" "unprognostic (1.13e-1)" "unprognostic (8.19e-2)" "unprognostic (1.20e-1)" "unprognostic (1.73e-1)" "unprognostic (1.68e-1)" "unprognostic (1.58e-1)" "unprognostic (1.68e-2)" PRSS2 TRY2 ENSG00000275896 "Serine protease 2" P07478 7 142760398-142774564 "Enzymes, Human disease related genes, Plasma proteins, Predicted secreted proteins" Digestion "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 460 "pancreas: 229146.3" "Cell type enriched" "Detected in some" 27 "Pancreatic acinar cells: 159286.7" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 65 "Pancreatic Adenocarcinoma (TCGA): 4249.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "basophil: 4.1;T-reg: 2.9" "Group enriched" "Detected in many" 8 "granulocytes: 4.1;T-cells: 2.9" "Cancer enhanced" "Detected in many" "Myeloma: 203.2;pancreatic cancer: 63.8" "HPA062452, HPA063471" Supported Approved "Endoplasmic reticulum,Vesicles" "Secreted to digestive system" Enzyme NA NA 360000000 "Cluster 8: Pancreas - Proteolysis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 5: Pancreatic acinar cells - Pancreatic exocrine secretion" 6 Vesicles "Endoplasmic reticulum" "HPA062452: , HPA063471: " "unprognostic (3.08e-1)" "unprognostic (2.36e-2)" "unprognostic (1.56e-1)" "unprognostic (7.84e-2)" "unprognostic (3.41e-1)" "unprognostic (8.41e-3)" "unprognostic (1.74e-1)" "unprognostic (2.51e-2)" "unprognostic (3.65e-3)" "unprognostic (2.13e-2)" "unprognostic (1.01e-1)" "unprognostic (8.08e-2)" "unprognostic (1.13e-2)" "unprognostic (1.45e-2)" "potential prognostic unfavorable (1.19e-4)" PRSS21 "ESP-1, TEST1" ENSG00000007038 "Serine protease 21" Q9Y6M0 16 2817180-2826304 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "testis: 81.8" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 136.7;Early primary spermatocytes: 305.1;Early spermatids: 59.3;Late primary spermatocytes: 94.2;Late spermatids: 298.5" "Cell type enriched" "Detected in single" 4 "leukocyte: 2.4" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 22.2" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "basophil: 16.2;eosinophil: 33.0" "Lineage enriched" "Detected in all" 7 "granulocytes: 33.0" "Cancer enhanced" "Detected in many" "cervical cancer: 23.1" "Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA008477 Enhanced Approved "Cytosol,Mid piece,Principal piece" "Intracellular and membrane" Enzyme NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 79: Testis - Spermatogenesis" "Cluster 47: Leukemia - Hemostasis" "Cluster 3: Early primary spermatocytes - Early meiosis" 1 "Cytosol, Mid piece, Principal piece" "HPA008477: " "unprognostic (1.27e-2)" "unprognostic (2.63e-2)" "unprognostic (1.88e-1)" "unprognostic (9.79e-2)" "unprognostic (7.16e-2)" "unprognostic (2.41e-1)" "unprognostic (3.05e-2)" "unprognostic (1.46e-1)" "unprognostic (1.85e-2)" "unprognostic (2.17e-1)" "unprognostic (4.03e-2)" "unprognostic (3.73e-1)" "unprognostic (1.42e-1)" "unprognostic (9.44e-2)" "unprognostic (6.97e-3)" "unprognostic (2.43e-1)" "unprognostic (9.83e-3)" "unprognostic (1.53e-1)" "unprognostic (1.02e-1)" "unprognostic (3.35e-1)" "unprognostic (5.18e-3)" "unprognostic (4.72e-2)" "unprognostic (4.47e-1)" PRSS22 "BSSP-4, hBSSP-4, SP001LA" ENSG00000005001 "Serine protease 22" Q9GZN4 16 2852730-2858170 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 77.9;salivary gland: 25.9;vagina: 23.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 17.8;Conjunctival goblet cells: 27.2;Cytotrophoblasts: 20.8;Esophageal apical cells: 151.3;Fallopian secretory cells: 18.1;Papillary tip epithelial cells: 24.1;Renal collecting duct principal cells: 19.1;Renal connecting tubule cells: 16.5;Salivary duct cells: 18.1;Urothelial cells: 40.9" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 24.6" "Breast - Breast glandular cells, Colon - Colon enterocytes, Liver - Cholangiocytes, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells" "Region enhanced" "Detected in some" "cerebral cortex: 2.6" "Low region specificity" "Detected in all" HPA049161 Approved "Secreted in other tissues" Enzyme NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 11 "HPA049161: " "unprognostic (4.40e-1)" "unprognostic (3.33e-1)" "unprognostic (3.51e-1)" "unprognostic (9.10e-2)" "unprognostic (3.19e-2)" "unprognostic (2.19e-1)" "unprognostic (2.11e-1)" "unprognostic (1.80e-2)" "unprognostic (2.56e-1)" "unprognostic (1.75e-2)" "unprognostic (6.77e-2)" "unprognostic (1.07e-1)" "unprognostic (8.36e-3)" "unprognostic (1.14e-1)" "unprognostic (3.33e-2)" "unprognostic (6.35e-3)" "unprognostic (3.92e-2)" "unprognostic (4.36e-1)" "unprognostic (3.07e-1)" "unprognostic (1.15e-1)" "unprognostic (2.14e-2)" "potential prognostic favorable (1.08e-4)" "unprognostic (2.08e-1)" PRSS23 "SIG13, SPUVE" ENSG00000150687 "Serine protease 23" O95084 11 86791059-86952910 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 233.3" "Cell type enhanced" "Detected in many" "Adipocytes: 999.5;Conjunctival goblet cells: 1401.0;Decidual stromal cells: 580.8;Hepatic stellate cells: 522.8;Respiratory basal cells: 1028.3;Respiratory deuterosomal cells: 970.3;Respiratory secretory cells: 1714.5;Vascular endothelial cells: 508.1" "Cell type enhanced" "Detected in all" "endothelial cell: 235.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 104.9" "Group enriched" "Detected in many" 25 "NK-cells: 34.2;T-cells: 104.9" "Low cancer specificity" "Detected in all" "Colon - Smooth muscle cells, Liver - Vascular endothelial cells, Spleen - Fibroblasts_1, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030591 Uncertain "Secreted to blood" Enzyme NA NA 400000 "Cluster 15: NK-cells - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 12: Non-specific - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 4 "HPA030591: " "unprognostic (2.36e-1)" "unprognostic (2.09e-1)" "unprognostic (2.94e-1)" "unprognostic (2.04e-2)" "unprognostic (3.12e-2)" "unprognostic (1.28e-2)" "unprognostic (3.63e-3)" "unprognostic (8.79e-2)" "unprognostic (2.81e-3)" "unprognostic (2.98e-1)" "potential prognostic favorable (4.06e-8)" "unprognostic (1.39e-3)" "unprognostic (3.20e-3)" "unprognostic (1.31e-2)" "unprognostic (1.93e-1)" "potential prognostic unfavorable (5.79e-4)" "unprognostic (8.78e-3)" "unprognostic (4.18e-3)" "unprognostic (6.68e-2)" "unprognostic (1.33e-1)" "unprognostic (1.08e-3)" "unprognostic (1.94e-2)" "unprognostic (1.28e-1)" "unprognostic (1.68e-1)" "unprognostic (8.41e-2)" "unprognostic (4.09e-2)" "unprognostic (4.25e-2)" "unprognostic (2.55e-3)" "unprognostic (7.69e-2)" "unprognostic (1.54e-3)" "unprognostic (2.55e-1)" PRSS27 "CAPH2, MPN" ENSG00000172382 "Serine protease 27" Q9BQR3 16 2712419-2720551 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "cervix: 101.3;esophagus: 374.0;vagina: 125.1" "Cell type enriched" "Detected in many" 73 "Esophageal apical cells: 7187.0" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 27.3;Head and Neck Squamous Cell Carcinoma (TCGA): 37.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 4.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB024920, HPA028848" Approved Approved Vesicles "Secreted to digestive system" Enzyme NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 84: Apical squamous epithelium - Cornification" 1 Vesicles "CAB024920: , HPA028848: " "unprognostic (8.67e-2)" "unprognostic (6.28e-3)" "unprognostic (1.88e-1)" "unprognostic (1.47e-1)" "unprognostic (8.07e-2)" "unprognostic (2.76e-2)" "unprognostic (3.29e-1)" "unprognostic (2.61e-1)" "unprognostic (1.09e-1)" "unprognostic (2.17e-1)" "unprognostic (3.65e-1)" "unprognostic (2.97e-1)" "unprognostic (4.24e-2)" "unprognostic (2.75e-2)" "unprognostic (8.08e-3)" "unprognostic (3.27e-2)" "unprognostic (1.81e-1)" "unprognostic (2.12e-1)" "unprognostic (2.39e-3)" "unprognostic (1.29e-1)" PRSS3 "PRSS4, TRY3, TRY4" ENSG00000010438 "Serine protease 3" P35030 9 33750679-33799231 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 238 "pancreas: 29336.6" "Group enriched" "Detected in many" 5 "Esophageal apical cells: 4350.8;Pancreatic acinar cells: 9291.5" "Cell type enhanced" "Detected in all" "upper rhombic lip: 82.0" "Group enriched" "Detected in many" 6 "Colon Adenocarcinoma (TCGA): 175.4;Pancreatic Adenocarcinoma (TCGA): 254.3;Rectum Adenocarcinoma (TCGA): 185.4;Stomach Adenocarcinoma (TCGA): 120.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 104 "basophil: 159.5" "Lineage enriched" "Detected in many" 104 "granulocytes: 159.5" "Cancer enhanced" "Detected in many" "colorectal cancer: 117.9" "Adrenal gland - Adrenal medulla cells, Colon - Colon enterocytes, Stomach - Gastric mucous cells, Testis - Late spermatids" "HPA062452, HPA063471" Supported Approved "Endoplasmic reticulum,Vesicles" "Secreted to digestive system" Enzyme NA NA 530000000 "Cluster 46: Basophils - Proteolysis" "Cluster 8: Pancreas - Proteolysis" "Cluster 24: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Pancreatic acinar cells - Pancreatic exocrine secretion" Vesicles "Endoplasmic reticulum" "HPA062452: , HPA063471: " "unprognostic (2.37e-2)" "unprognostic (6.01e-2)" "unprognostic (3.84e-2)" "unprognostic (4.20e-2)" "unprognostic (3.77e-3)" "unprognostic (6.70e-2)" "unprognostic (2.88e-1)" "unprognostic (1.85e-1)" "unprognostic (9.58e-3)" "potential prognostic unfavorable (6.00e-5)" "unprognostic (1.25e-2)" "unprognostic (5.07e-2)" "unprognostic (3.50e-3)" "unprognostic (4.17e-3)" "unprognostic (1.77e-1)" "unprognostic (2.45e-1)" "unprognostic (7.48e-2)" "unprognostic (6.30e-3)" "unprognostic (9.92e-3)" "unprognostic (4.50e-2)" "unprognostic (2.12e-1)" "unprognostic (2.30e-1)" "unprognostic (3.34e-1)" "unprognostic (5.79e-3)" "unprognostic (3.62e-1)" "unprognostic (2.59e-1)" PRSS33 EOS ENSG00000103355 "Serine protease 33" Q8NF86 16 2783953-2787948 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 5 "fallopian tube: 4.6" "Cell type enriched" "Detected in some" 4 "Retinal pigment epithelial cells: 110.8" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 14.3;Skin Cutaneous Melanoma (TCGA): 11.9" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 68 "eosinophil: 1353.2" "Lineage enriched" "Detected in many" 390 "granulocytes: 1353.2" "Cancer enhanced" "Detected in some" "Bile duct cancer: 3.2;skin cancer: 4.9" "Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Undifferentiated cells (Pituitary gland)" "Not detected" "Not detected" "Region enhanced" "Detected in some" "basal ganglia: 4.0" "Secreted to blood" Enzyme NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 69: Skin cancer - ECM organization" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" "unprognostic (5.50e-1)" "unprognostic (4.33e-1)" "unprognostic (2.33e-2)" "unprognostic (6.13e-3)" "unprognostic (4.27e-2)" "unprognostic (8.66e-3)" "unprognostic (6.03e-3)" "unprognostic (3.64e-3)" "unprognostic (1.29e-1)" "unprognostic (3.63e-1)" "unprognostic (3.52e-3)" "unprognostic (2.48e-1)" "unprognostic (4.83e-1)" "unprognostic (2.63e-1)" PRSS35 "C6orf158, dJ223E3.1, MGC46520" ENSG00000146250 "Serine protease 35" Q8N3Z0 6 83512534-83525704 "Enzymes, Predicted secreted proteins" "Serine protease homolog" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 17.9;retina: 46.8" "Cell type enriched" "Detected in some" 14 "Müller glia: 415.6" "Cell type enhanced" "Detected in some" "astrocyte: 8.7;eccentric medium spiny neuron: 9.8" "Group enriched" "Detected in some" 4 "Glioblastoma Multiforme (TCGA): 4.7;Testicular Germ Cell Tumor (TCGA): 7.4" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 9 "MAIT T-cell: 19.5" "Lineage enriched" "Detected in single" 196 "T-cells: 19.5" "Group enriched" "Detected in many" 4 "Bone cancer: 34.4;Brain cancer: 15.4;testis cancer: 16.5" "Kidney - Ascending Loop of Henle cells, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "amygdala: 3.8;cerebellum: 4.9;cerebral cortex: 7.7;hippocampal formation: 7.0;olfactory bulb: 3.6" "HPA038787, HPA038788" Uncertain "Secreted in female reproductive system" Other NA NA "Cluster 1: T-cells - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 11: Muller glia cells - Retinal homeostasis" 1 "HPA038787: , HPA038788: " "unprognostic (2.70e-1)" "unprognostic (7.14e-2)" "potential prognostic favorable (7.13e-4)" "unprognostic (1.95e-1)" "unprognostic (5.00e-3)" "unprognostic (2.86e-2)" "unprognostic (1.06e-2)" "unprognostic (1.07e-1)" PRSS36 FLJ90661 ENSG00000178226 "Serine protease 36" Q5K4E3 16 31138926-31150083 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "pituitary gland: 2.4" "Cell type enhanced" "Detected in many" "Colonocytes: 16.7;Enterocytes: 43.2;Hofbauer cells: 34.7;Macrophages: 10.2;Pituitary stem cells: 15.2" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "eosinophil: 2.0" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Lung - Macrophages, Minor Salivary Gland - Macrophages, Skeletal muscle - Macrophages, Spleen - Neutrophils_2, Stomach - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA036079 Uncertain "Secreted to extracellular matrix" Enzyme NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 77: Intestine - Digestion" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" "HPA036079: " "unprognostic (2.02e-1)" "unprognostic (4.60e-3)" "unprognostic (6.08e-2)" "unprognostic (4.49e-2)" "unprognostic (5.71e-2)" "unprognostic (3.45e-2)" PRSS37 ENSG00000165076 "Serine protease 37" A4D1T9 7 141836300-141841487 "Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins" Fertilization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 87 "testis: 39.0" "Group enriched" "Detected in some" 33 "Early spermatids: 819.6;Late spermatids: 426.0" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA020541 Enhanced "Secreted in male reproductive system" Other NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" "HPA020541: " PRSS38 MPN2 ENSG00000185888 "Serine protease 38" A1L453 1 227815675-227846470 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 42 "testis: 4.1" "Cell type enriched" "Detected in some" 4 "Early primary spermatocytes: 46.9" "Low cell type specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" Enzyme NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 3: Early primary spermatocytes - Early meiosis" PRSS41 TESSP1 ENSG00000215148 "Serine protease 41" 16 2798470-2805304 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "testis: 1.4" "Group enriched" "Detected in some" 5 "Differentiating spermatogonia: 78.8;Early primary spermatocytes: 78.6" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Testicular Germ Cell Tumor (TCGA): 1.9" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 106 "eosinophil: 10.5" "Lineage enriched" "Detected in single" 106 "granulocytes: 10.5" "Cancer enhanced" "Detected in single" "Gastric cancer: 1.0" "Not detected" "Not detected" NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 21: Testis - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 106: Spermatogonia - Spermatogonial differentiation" "unprognostic (2.18e-1)" PRSS48 ESSPL ENSG00000189099 "Serine protease 48" Q7RTY5 4 151277161-151291862 "Enzymes, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 174.1;Epicardial cells: 45.5;Fibro-adipogenic progenitors: 33.3;Myonuclei: 47.6;Paneth cells: 50.3;Rod photoreceptor cells: 33.7;Salivary myoepithelial cells: 34.2;Tuft cells: 34.6" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 52.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA053801 Uncertain "Secreted - unknown location" Enzyme NA NA "Cluster 42: Choroid plexus - Mitochondria" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 2 "HPA053801: " "unprognostic (3.50e-2)" "unprognostic (4.43e-3)" PRSS50 "CT20, TSP50" ENSG00000283706 "Serine protease 50" Q9UI38 3 46712117-46717869 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Threonine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "pituitary gland: 18.2;testis: 51.3;thyroid gland: 17.4" "Cell type enhanced" "Detected in some" "Astrocytes: 1.9;Bergmann glia: 1.2;Choroid plexus epithelial cells: 1.3;Other brain neurons: 1.1" "Cell type enhanced" "Detected in some" "astrocyte: 3.0;lower rhombic lip: 2.0" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 10.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "cervical cancer: 2.3" "Adrenal gland - Adrenal medulla cells, Breast - Breast glandular cells, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA040768 Supported "Intracellular and membrane" Enzyme NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 28: Astrocytes - Homeostasis & neuron support" 16 "HPA040768: " "unprognostic (1.33e-1)" "unprognostic (4.53e-3)" "unprognostic (2.86e-1)" "unprognostic (1.41e-1)" "unprognostic (2.19e-1)" "unprognostic (4.82e-2)" "unprognostic (2.50e-1)" "unprognostic (1.47e-1)" "unprognostic (9.95e-2)" "unprognostic (1.05e-1)" "unprognostic (9.76e-2)" "unprognostic (1.21e-2)" PRSS51 ENSG00000253649 "Serine protease 51" A0A1B0GVH4 8 10482878-10547585 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 15 "brain: 18.0" "Cell type enhanced" "Detected in some" "Adipocytes: 16.1;Astrocytes: 6.7;Bergmann glia: 13.8;Brain excitatory neurons: 28.1;Brain inhibitory neurons: 11.1;Cardiomyocytes: 5.4;Early spermatids: 11.2;Epicardial cells: 15.9;Late spermatids: 6.1;Oligodendrocyte progenitor cells: 9.9;Proximal tubule cells: 4.5" "Cell type enhanced" "Detected in many" "upper rhombic lip: 67.6" "Not detected" "Not detected" "Region enhanced" "Detected in all" "cerebellum: 61.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 9.7;Rhabdoid: 4.6" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted in brain" "No annotated function" NA NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 2: Neurons - Nucleosome" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 2: Cerebellar granular cells - Neuronal signaling" "unprognostic (1.00e-1)" "unprognostic (9.93e-2)" "unprognostic (1.75e-1)" PRSS53 POL3S ENSG00000151006 "Serine protease 53" Q2L4Q9 16 31083437-31089628 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "liver: 9.8" "Cell type enhanced" "Detected in some" "Astrocytes: 3.4;Bergmann glia: 2.4;Brain excitatory neurons: 5.5;Brain inhibitory neurons: 5.0;Choroid plexus epithelial cells: 1.3;Microglia: 2.8;Oligodendrocyte progenitor cells: 2.1;Oligodendrocytes: 3.4;Other brain neurons: 4.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Adipose progenitor cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA034955, HPA034956" Uncertain "Secreted in other tissues" Enzyme NA NA "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 15: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 35: Neurons - Synaptic function & neurogenesis" 1 "HPA034955: , HPA034956: " "unprognostic (4.54e-2)" "unprognostic (6.30e-3)" "unprognostic (2.15e-1)" "potential prognostic unfavorable (1.88e-5)" "unprognostic (2.24e-1)" PRSS54 "CT67, FLJ25339, KLKBL4" ENSG00000103023 "Serine protease 54" Q6PEW0 16 58279997-58295047 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Serine protease homolog" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 286 "testis: 38.7" "Group enriched" "Detected in some" 21 "Early spermatids: 674.7;Late primary spermatocytes: 247.1;Late spermatids: 291.3" "Cell type enhanced" "Detected in some" "ependymal cell: 4.4" "Group enriched" "Detected in some" 4 "Prostate Adenocarcinoma (TCGA): 1.1;Uterine Corpus Endometrial Carcinoma (TCGA): 2.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA041549 Enhanced "Secreted in male reproductive system" Other NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 17: Choroid plexus - Cilium" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" "HPA041549: " "unprognostic (4.00e-1)" "unprognostic (9.27e-2)" PRSS55 "CT153, T-SP1, UNQ9391" ENSG00000184647 "Serine protease 55" Q6UWB4 8 10525532-10554166 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 54 "testis: 26.0" "Group enriched" "Detected in some" 10 "Early spermatids: 174.1;Late primary spermatocytes: 101.5;Late spermatids: 49.9" "Cell type enhanced" "Detected in many" "hippocampal CA1-3: 12.0" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA027977 Approved Acrosome "Intracellular and membrane" Enzyme NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" Acrosome "HPA027977: " PRSS56 ENSG00000237412 "Serine protease 56" P0CW18 2 232520388-232525716 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.4;retina: 4.9;skeletal muscle: 9.1" "Group enriched" "Detected in some" 5 "Early spermatids: 36.8;Müller glia: 50.2" "Cell type enhanced" "Detected in some" "lower rhombic lip: 8.7;midbrain-derived inhibitory: 5.1;splatter: 4.2" "Group enriched" "Detected in many" 5 "Bladder Urothelial Carcinoma (TCGA): 18.5;Colon Adenocarcinoma (TCGA): 6.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 7.1;head and neck cancer: 15.7" "Testis - Late spermatids" "Group enriched" "Detected in some" 10 "basal ganglia: 1.9;olfactory bulb: 4.2" "Region enhanced" "Detected in many" "olfactory bulb: 18.6" NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 11: Muller glia cells - Retinal homeostasis" "unprognostic (8.75e-2)" "unprognostic (2.97e-1)" "unprognostic (4.22e-1)" "unprognostic (7.30e-2)" "unprognostic (3.34e-2)" "unprognostic (1.97e-1)" "unprognostic (3.49e-1)" "unprognostic (3.53e-1)" "unprognostic (5.85e-1)" PRSS57 "PRSSL1, UNQ782" ENSG00000185198 "Serine protease 57" Q6UWY2 19 685546-695498 "Enzymes, Predicted secreted proteins" "Heparin-binding, Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 99 "bone marrow: 155.9" "Cell type enhanced" "Detected in some" "Erythrocyte progenitors: 20.8;Hematopoietic stem cells: 190.7;Megakaryocyte progenitors: 65.7;Megakaryocyte-Erythroid progenitors: 137.5;Monocyte progenitors: 37.3;Neutrophil progenitors: 57.9;Thymocytes: 60.1" "Cell type enriched" "Detected in single" 9 "leukocyte: 4.1" "Cancer enriched" "Detected in single" 7 "Pancreatic Adenocarcinoma (TCGA): 4.2" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "basophil: 5.9" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in single" 229 "Leukemia: 199.5" "Lung - Neutrophils_1, Spleen - Neutrophils_1" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" Enzyme NA NA 220000 "Cluster 41: Basophils - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" "unprognostic (1.60e-1)" PRSS58 TRYX3 ENSG00000258223 "Serine protease 58" Q8IYP2 7 142252143-142258058 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 181 "testis: 24.4" "Group enriched" "Detected in some" 41 "Early spermatids: 749.5;Late spermatids: 257.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" Enzyme NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 11: Neuronal - Sensory perception" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" PRSS8 CAP1 ENSG00000052344 "Serine protease 8" Q16651 16 31131433-31135727 "Enzymes, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 231.3" "Cell type enhanced" "Detected in many" "Breast lactating cells: 223.0;Colonocytes: 293.6;Enterocytes: 335.8;Epididymal principal cells: 320.9;Esophageal apical cells: 887.1;Extravillous trophoblasts: 1023.7;Foveolar cells: 272.4;Migrating cytotrophoblasts: 313.1;Syncytiotrophoblasts: 689.0" "Cell type enhanced" "Detected in single" "choroid plexus epithelial cell: 1.6" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in all" 5 "cerebellum: 5.0;choroid plexus: 14.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells, Thyroid gland - Thyroid glandular cells" "Region enriched" "Detected in single" 8 "hippocampal formation: 1.4" "Low region specificity" "Detected in some" HPA030436 Uncertain "Secreted - unknown location" Enzyme NA NA 810000 "Cluster 60: Stomach - Digestion" "Cluster 5: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." 32 "HPA030436: " "unprognostic (6.75e-2)" "unprognostic (5.71e-2)" "unprognostic (6.56e-2)" "unprognostic (3.39e-3)" "unprognostic (2.30e-1)" "unprognostic (1.63e-2)" "unprognostic (4.09e-3)" "unprognostic (3.45e-1)" "potential prognostic favorable (2.24e-6)" "unprognostic (2.72e-3)" "potential prognostic favorable (2.39e-4)" "unprognostic (5.38e-2)" "potential prognostic favorable (8.24e-4)" "unprognostic (2.97e-1)" "unprognostic (1.89e-1)" "unprognostic (4.67e-2)" "unprognostic (3.25e-2)" "unprognostic (5.80e-2)" "unprognostic (1.04e-1)" "unprognostic (6.57e-3)" "unprognostic (1.57e-1)" "unprognostic (1.10e-1)" "unprognostic (1.00e-1)" "unprognostic (1.83e-2)" "unprognostic (2.25e-1)" "unprognostic (2.10e-2)" "unprognostic (3.36e-1)" "unprognostic (2.73e-2)" "unprognostic (9.42e-2)" PRTFDC1 HHGP ENSG00000099256 "Phosphoribosyl transferase domain containing 1" Q9NRG1 10 24848614-24952606 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 139.8;Bergmann glia: 134.3;Ependymal cells: 127.2;Lactotrophs: 87.9;Megakaryocyte progenitors: 94.9;Megakaryocytes: 98.9;Müller glia: 86.8;Oligodendrocyte progenitor cells: 104.8;Oligodendrocytes: 139.8;Platelets: 108.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "NK-cell: 4.5" "Lineage enriched" "Detected in single" 8 "NK-cells: 4.5" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 98.7" "Adipose subcutaneous - Adipose progenitor cells, Kidney - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" HPA021458 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 150000 "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 28: Astrocytes - Homeostasis & neuron support" 17 Nucleoplasm "Golgi apparatus, Cytosol" "HPA021458: " "unprognostic (1.02e-2)" "unprognostic (4.76e-1)" "unprognostic (1.86e-1)" "unprognostic (4.39e-1)" "unprognostic (2.31e-1)" "unprognostic (3.41e-1)" "unprognostic (3.09e-2)" "potential prognostic favorable (1.48e-5)" "unprognostic (2.73e-1)" "potential prognostic unfavorable (1.83e-8)" "unprognostic (1.70e-1)" "unprognostic (9.30e-2)" "unprognostic (1.15e-1)" "unprognostic (1.13e-2)" "potential prognostic unfavorable (3.00e-4)" "unprognostic (3.95e-2)" "unprognostic (7.01e-3)" "unprognostic (2.34e-1)" "unprognostic (1.16e-1)" "unprognostic (2.97e-1)" "unprognostic (1.25e-1)" "unprognostic (6.20e-2)" "unprognostic (2.64e-1)" "unprognostic (3.19e-1)" "unprognostic (2.50e-1)" "unprognostic (1.58e-2)" "unprognostic (9.99e-2)" "unprognostic (2.59e-2)" "unprognostic (2.16e-1)" "unprognostic (2.60e-3)" "unprognostic (3.97e-2)" PRTG "FLJ25756, IGDCC5" ENSG00000166450 Protogenin Q2VWP7 15 55611544-55743152 "Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 9.6;thyroid gland: 10.0" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 95.7;Alveolar cells type 2: 126.1;Bergmann glia: 173.0;Cone photoreceptor cells: 287.7;Distal convoluted tubule cells: 85.6;Endometrial stromal cells: 86.6;Pituitary stem cells: 79.2;Renal collecting duct principal cells: 148.4;Renal connecting tubule cells: 104.6;Rod photoreceptor cells: 184.1" "Cell type enhanced" "Detected in many" "Bergmann glia: 195.3;endothelial cell: 282.9" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 4.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 15 "testis cancer: 159.2" "Liver - Hepatic stellate cells, Lung - Alveolar cells type 2, Testis - Early spermatids, Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA032137, HPA032138" Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 42: Retina - Visual perception" "Cluster 19: Astrocytes - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" Cytosol "Vesicles, Plasma membrane" "HPA032137: , HPA032138: " "unprognostic (4.33e-3)" "unprognostic (1.56e-1)" "unprognostic (1.27e-3)" "unprognostic (6.52e-3)" "unprognostic (1.41e-1)" "unprognostic (2.84e-2)" "unprognostic (2.36e-1)" "unprognostic (3.16e-2)" "unprognostic (1.51e-1)" "unprognostic (1.77e-1)" "unprognostic (6.60e-2)" "unprognostic (3.54e-2)" PRTN3 "ACPA, AGP7, C-ANCA, MBT, P29, PR-3" ENSG00000196415 "Proteinase 3" P24158 19 840999-848175 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 52 "bone marrow: 1978.0" "Group enriched" "Detected in some" 55 "Monocyte progenitors: 320.2;Neutrophil progenitors: 339.3" "Cell type enhanced" "Detected in some" "upper-layer intratelencephalic: 2.7" "Cancer enhanced" "Detected in single" "Stomach Adenocarcinoma (TCGA): 2.0" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 8 "neutrophil: 2.0" "Lineage enriched" "Detected in single" 8 "granulocytes: 2.0" "Cancer enriched" "Detected in some" 225 "Leukemia: 507.6" "Lung - Neutrophils_1, Spleen - Neutrophils_1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA005938, CAB017558" Enhanced Approved Vesicles,Cytosol "Secreted to blood" Enzyme NA NA 2500000 "Cluster 15: Bone marrow - Innate immune response" "Cluster 33: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 41 Cytosol Vesicles "CAB017558: , HPA005938: " "unprognostic (2.98e-1)" "unprognostic (8.17e-2)" PRUNE1 "DRES-17, H-PRUNE, HTCD37, PRUNE" ENSG00000143363 "Prune exopolyphosphatase 1" Q86TP1 1 151008420-151035713 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant, Intellectual disability, Neurodegeneration, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 81.6;Late spermatids: 99.1;Megakaryocytes: 74.2;Platelets: 177.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028411 Uncertain Supported Cytosol NA NA 42000 "Cluster 33: Non-specific - ATP binding" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 16: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 47: Platelets - Hemostasis" 10 Cytosol "HPA028411: " "unprognostic (5.50e-2)" "unprognostic (2.99e-1)" "unprognostic (2.32e-2)" "unprognostic (3.19e-1)" "potential prognostic favorable (2.11e-4)" "unprognostic (3.71e-1)" "unprognostic (1.02e-1)" "unprognostic (1.61e-1)" "unprognostic (6.87e-3)" "unprognostic (3.29e-3)" "unprognostic (5.79e-2)" "unprognostic (5.47e-3)" "unprognostic (1.00e-3)" "unprognostic (3.32e-1)" "unprognostic (1.90e-2)" "unprognostic (2.94e-3)" "unprognostic (7.37e-2)" "unprognostic (4.47e-1)" "unprognostic (2.09e-2)" "unprognostic (4.16e-1)" "unprognostic (1.73e-1)" "unprognostic (8.23e-2)" "unprognostic (1.35e-1)" "unprognostic (3.92e-2)" "unprognostic (2.18e-2)" "unprognostic (4.36e-2)" "unprognostic (3.83e-2)" "unprognostic (3.16e-2)" "unprognostic (1.08e-1)" PRUNE2 "A214N16.3, bA214N16.3, BMCC1, BNIPXL, C9orf65, KIAA0367" ENSG00000106772 "Prune homolog 2 with BCH domain" Q8WUY3 9 76611376-76906114 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 1074.3;Gonadotrophs: 704.3;Lactotrophs: 684.2;Oligodendrocytes: 1226.8;Proximal tubule cells: 704.1;Retinal ganglion cells: 1135.7;Smooth muscle cells: 1016.3;Somatotrophs: 563.7;Thymic myoid cells: 580.6" "Cell type enhanced" "Detected in all" "oligodendrocyte: 1535.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 50.0" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Adrenal gland - Adrenal medulla cells, Prostate - Smooth muscle cells, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017269, HPA022470, HPA031079" Uncertain Approved Cytosol NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 62: Smooth muscle cells - Muscle contraction" 13 Cytosol "HPA017269: , HPA022470: , HPA031079: " "unprognostic (8.46e-3)" "unprognostic (2.33e-1)" "unprognostic (2.11e-1)" "unprognostic (4.65e-2)" "unprognostic (3.65e-1)" "unprognostic (1.55e-2)" "unprognostic (2.29e-1)" "unprognostic (1.20e-1)" "unprognostic (5.06e-3)" "potential prognostic favorable (6.04e-11)" "unprognostic (1.31e-3)" "unprognostic (2.58e-2)" "unprognostic (2.61e-2)" "unprognostic (2.70e-1)" "unprognostic (1.93e-1)" "unprognostic (5.12e-2)" "unprognostic (2.01e-2)" "unprognostic (1.55e-1)" "unprognostic (8.06e-3)" "unprognostic (8.56e-2)" "unprognostic (2.27e-2)" "unprognostic (1.90e-1)" "unprognostic (1.46e-1)" "unprognostic (1.97e-1)" "unprognostic (5.90e-2)" "unprognostic (2.41e-1)" "potential prognostic unfavorable (6.87e-4)" "unprognostic (3.83e-1)" PRX KIAA1620 ENSG00000105227 Periaxin Q9BXM0 19 40393766-40414793 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Charcot-Marie-Tooth disease, Dejerine-Sottas syndrome, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 33.7" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 50.8;Epididymal basal cells: 44.2;Hematopoietic stem cells: 50.5;Schwann cells: 100.9;Vascular endothelial cells: 28.8" "Cell type enriched" "Detected in some" 14 "endothelial cell: 53.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Region enriched" "Detected in all" 8 "spinal cord: 249.7" HPA001868 Enhanced Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 5: Rhabdoid - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 3 "Golgi apparatus, Vesicles, Plasma membrane" "HPA001868: " "unprognostic (1.51e-1)" "unprognostic (1.29e-2)" "unprognostic (1.95e-1)" "unprognostic (2.95e-3)" "unprognostic (5.03e-2)" "unprognostic (1.17e-1)" "unprognostic (1.78e-1)" "potential prognostic unfavorable (3.80e-4)" "unprognostic (1.52e-1)" "unprognostic (2.41e-1)" "validated prognostic favorable (6.55e-7)" "validated prognostic favorable (9.53e-4)" "unprognostic (3.59e-3)" "unprognostic (3.39e-2)" "unprognostic (1.33e-1)" "unprognostic (2.70e-3)" "unprognostic (4.04e-3)" "unprognostic (2.77e-2)" "unprognostic (2.54e-1)" "unprognostic (4.56e-2)" "unprognostic (1.52e-1)" "unprognostic (6.33e-2)" "unprognostic (3.04e-2)" "unprognostic (4.72e-2)" "unprognostic (2.06e-1)" "unprognostic (4.32e-2)" "unprognostic (1.74e-1)" "unprognostic (1.25e-1)" "unprognostic (2.26e-1)" "unprognostic (9.95e-2)" "unprognostic (1.44e-1)" PRXL2A "Adrx, C10orf58, FAM213A, MGC4248, PAMM" ENSG00000122378 "Peroxiredoxin like 2A" Q9BRX8 10 80407829-80437115 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Antioxidant "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 380.6" "Cell type enhanced" "Detected in many" "Endometrial luminal cells: 359.7;Epididymal principal cells: 639.9;Esophageal basal cells: 605.5;Esophageal suprabasal cells: 375.9;Retinal pigment epithelial cells: 763.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 10 "plasmacytoid DC: 166.4" "Lineage enriched" "Detected in all" 10 "dendritic cells: 166.4" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009025, HPA024565" Enhanced "Secreted in other tissues" Other NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 36: Brain & Liver - Signaling" "Cluster 39: Astrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 5 "HPA009025: , HPA024565: " "potential prognostic favorable (1.49e-4)" "unprognostic (2.73e-3)" "unprognostic (1.27e-1)" "unprognostic (9.64e-3)" "unprognostic (2.44e-1)" "unprognostic (2.92e-2)" "unprognostic (1.77e-3)" "unprognostic (3.42e-2)" "unprognostic (5.00e-1)" "potential prognostic favorable (2.02e-7)" "unprognostic (6.91e-3)" "unprognostic (4.35e-1)" "unprognostic (1.49e-1)" "unprognostic (1.47e-1)" "unprognostic (2.24e-1)" "unprognostic (1.75e-1)" "unprognostic (2.77e-1)" "unprognostic (1.75e-1)" "unprognostic (1.71e-1)" "unprognostic (7.63e-2)" "unprognostic (2.62e-2)" "unprognostic (1.49e-2)" "unprognostic (4.64e-2)" "unprognostic (2.67e-1)" "unprognostic (6.68e-2)" "unprognostic (1.12e-1)" "unprognostic (3.01e-2)" "unprognostic (1.41e-1)" "unprognostic (1.08e-1)" PRXL2B "C1orf93, FAM213B, MGC26818" ENSG00000157870 "Peroxiredoxin like 2B" Q8TBF2 1 2586491-2591469 "Enzymes, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 41.2" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 6.8;Brain inhibitory neurons: 7.3;Enterocytes: 12.0;Ependymal cells: 9.4;Gastric progenitor cells: 12.8;Megakaryocytes: 6.2;Other brain neurons: 13.0;Papillary tip epithelial cells: 9.3;Renal collecting duct principal cells: 10.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006403 Approved Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 2 Cytosol Nucleoplasm "HPA006403: " "unprognostic (4.29e-3)" "unprognostic (3.05e-2)" "unprognostic (9.76e-3)" "unprognostic (5.39e-2)" "unprognostic (6.27e-2)" "unprognostic (2.62e-1)" "unprognostic (1.64e-1)" "unprognostic (5.96e-2)" "unprognostic (1.99e-2)" "potential prognostic favorable (7.06e-8)" "unprognostic (1.04e-1)" "unprognostic (4.47e-2)" "potential prognostic unfavorable (7.59e-4)" "unprognostic (8.89e-2)" "unprognostic (1.83e-1)" "unprognostic (9.36e-3)" "unprognostic (2.82e-1)" "unprognostic (9.44e-3)" "unprognostic (2.59e-1)" "potential prognostic unfavorable (9.43e-4)" "unprognostic (1.38e-1)" "unprognostic (2.82e-1)" "unprognostic (2.27e-1)" "unprognostic (1.37e-1)" "unprognostic (3.24e-1)" "unprognostic (3.50e-2)" "unprognostic (3.83e-1)" "unprognostic (2.78e-2)" "unprognostic (2.11e-1)" PRXL2C "AAED1, C9orf21" ENSG00000158122 "Peroxiredoxin like 2C" Q7RTV5 9 96639577-96655317 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Megakaryocytes: 105.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 46.1" "Lineage enriched" "Detected in all" 4 "granulocytes: 46.1" "Low cancer specificity" "Detected in all" "Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021294 Approved NA NA "Cluster 32: Basophils - Transcription" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 30: White matter - Myelination" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 103: Non-specific - Basic cellular processes" 1 "HPA021294: " "unprognostic (1.38e-1)" "unprognostic (2.40e-2)" "unprognostic (1.06e-1)" "unprognostic (2.43e-3)" "unprognostic (2.94e-3)" "unprognostic (2.13e-2)" "unprognostic (2.18e-3)" "unprognostic (1.75e-1)" "unprognostic (1.13e-2)" "potential prognostic favorable (2.36e-4)" "unprognostic (2.72e-3)" "unprognostic (3.21e-2)" "unprognostic (1.72e-2)" "unprognostic (2.99e-1)" "unprognostic (9.10e-2)" "unprognostic (1.23e-2)" "unprognostic (8.00e-2)" "unprognostic (4.22e-2)" "unprognostic (3.40e-2)" "unprognostic (8.20e-3)" "unprognostic (2.32e-2)" "unprognostic (1.82e-1)" "unprognostic (5.88e-2)" "unprognostic (4.33e-2)" "unprognostic (4.29e-2)" "unprognostic (5.83e-2)" "unprognostic (2.46e-1)" "potential prognostic unfavorable (8.16e-4)" "unprognostic (7.04e-2)" PRY "PRY1, PTPN13LY" ENSG00000169789 "PTPN13 like Y-linked" O14603 Y 22490397-22514637 "Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 9 "epididymis: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Rhabdoid: 2.0" NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" PRY2 PTPN13LY2 ENSG00000169807 "PTPN13 like Y-linked 2" O14603 Y 22071756-22096007 "Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 60: Prostate cancer - Unknown function" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" PSAP "GLBA, SAP1, SAP2" ENSG00000197746 Prosaposin P07602 10 71816298-71851251 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Lipid metabolism, Sphingolipid metabolism" "Disease variant, Gangliosidosis, Gaucher disease, Leukodystrophy, Metachromatic leukodystrophy, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 1296.3;Kupffer cells: 3369.9;Macrophages: 1473.0;monocytes: 1854.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "intermediate monocyte: 11625.4" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Fibroblasts, Lung - Macrophages, Pancreas - Macrophages, Skin - Fibroblasts_2, Spleen - Macrophages, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004426, CAB004647" Supported Supported Vesicles "Intracellular and membrane" Other NA NA 44000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 13 Vesicles "CAB004647: , HPA004426: " "unprognostic (2.53e-2)" "unprognostic (6.82e-3)" "unprognostic (1.36e-3)" "unprognostic (3.42e-1)" "unprognostic (3.51e-1)" "unprognostic (2.56e-2)" "unprognostic (4.12e-1)" "unprognostic (1.30e-1)" "unprognostic (1.66e-1)" "unprognostic (7.95e-2)" "potential prognostic favorable (6.58e-6)" "unprognostic (4.35e-1)" "unprognostic (5.57e-2)" "potential prognostic unfavorable (8.91e-4)" "unprognostic (1.57e-2)" "unprognostic (3.16e-2)" "unprognostic (1.21e-1)" "unprognostic (5.89e-2)" "potential prognostic unfavorable (9.02e-4)" "unprognostic (1.67e-2)" "unprognostic (1.34e-1)" "unprognostic (2.79e-3)" "unprognostic (1.82e-1)" "unprognostic (6.50e-2)" "unprognostic (4.56e-2)" "unprognostic (2.51e-3)" "unprognostic (4.85e-2)" "unprognostic (4.38e-2)" "unprognostic (4.47e-2)" "unprognostic (1.37e-1)" "unprognostic (2.53e-1)" PSAPL1 ENSG00000178597 "Prosaposin like 1" Q6NUJ1 4 7430285-7434930 "Predicted secreted proteins" "Lipid metabolism, Sphingolipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "skin 1: 95.9;stomach 1: 36.4" "Cell type enriched" "Detected in some" 138 "Foveolar cells: 543.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Skin Cutaneous Melanoma (TCGA): 2.4;Stomach Adenocarcinoma (TCGA): 2.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 2.3;Esophageal cancer: 2.0" "Adipose visceral - Mesothelial cells, Skin - Keratinocyte (granular), Stomach - Gastric mucous cells, Testis - Sertoli cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038013, HPA038482" Approved Enhanced Cytosol "Secreted - unknown location" Other NA NA 3700 "Cluster 9: Skin - Hair follicle development" "Cluster 6: Non-specific - Immune response" "Cluster 66: Non-specific - Mitochondria" "Cluster 68: Foveolar cells - Mucosal defense" 1 Cytosol "HPA038013: , HPA038482: " "unprognostic (1.37e-2)" "unprognostic (2.60e-1)" "unprognostic (2.28e-1)" "unprognostic (5.24e-3)" PSAT1 "PSA, PSAT" ENSG00000135069 "Phosphoserine aminotransferase 1" Q9Y617 9 78297125-78330093 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Serine biosynthesis" "Aminotransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 153.9;kidney: 127.7;liver: 250.5;pancreas: 121.8" "Cell type enhanced" "Detected in many" "Astrocytes: 101.6;Endometrial luminal cells: 337.1;Ependymal cells: 109.9;Epididymal principal cells: 80.0;Esophageal basal cells: 88.3;Gastric chief cells: 77.5;Hepatocytes: 201.1;Ocular epithelial cells: 90.9;Oligodendrocyte progenitor cells: 80.6;Oligodendrocytes: 110.6;Proximal tubule cells: 73.8;Retinal pigment epithelial cells: 98.0" "Cell type enhanced" "Detected in all" "astrocyte: 114.5;ependymal cell: 127.1;oligodendrocyte: 125.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 15.2" "Lineage enriched" "Detected in many" 5 "T-cells: 15.2" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Prostate - Prostate glandular cells, Skin - Keratinocyte (other), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB014882, CAB040567, HPA042924" Enhanced Enhanced Cytosol NA NA 4200000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 36: Brain & Liver - Signaling" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 19 Cytosol "CAB014882: , CAB040567: , HPA042924: " "unprognostic (1.60e-1)" "unprognostic (1.75e-2)" "unprognostic (1.86e-1)" "unprognostic (1.76e-1)" "unprognostic (1.03e-1)" "unprognostic (5.37e-3)" "unprognostic (4.13e-2)" "unprognostic (6.84e-2)" "unprognostic (2.34e-1)" "unprognostic (6.67e-3)" "potential prognostic unfavorable (3.50e-7)" "unprognostic (6.47e-3)" "potential prognostic unfavorable (6.76e-5)" "unprognostic (2.51e-3)" "unprognostic (1.28e-1)" "unprognostic (9.94e-2)" "unprognostic (1.77e-1)" "unprognostic (1.76e-2)" "unprognostic (2.85e-3)" "unprognostic (8.51e-2)" "unprognostic (5.10e-2)" "unprognostic (1.93e-2)" "unprognostic (3.04e-2)" "unprognostic (1.11e-1)" "unprognostic (2.53e-2)" "unprognostic (1.52e-1)" "unprognostic (4.29e-2)" "unprognostic (6.52e-3)" "unprognostic (1.12e-1)" "unprognostic (5.09e-3)" "unprognostic (2.50e-1)" PSCA lncPSCA ENSG00000167653 "Prostate stem cell antigen" O43653 8 142670308-142682725 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "stomach 1: 3010.1" "Group enriched" "Detected in many" 5 "Esophageal apical cells: 9592.0;Foveolar cells: 7558.7;Parietal cells: 10610.9;Prostatic club cells: 3521.6" "Low cell type specificity" "Detected in some" "Cancer enriched" "Detected in many" 4 "Bladder Urothelial Carcinoma (TCGA): 1552.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "pancreatic cancer: 205.3" "Lung - Respiratory ciliated cells, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Region enriched" "Detected in many" 8 "spinal cord: 50.6" "HPA030783, HPA056418" Approved Supported "Plasma membrane" NA NA "Cluster 60: Stomach - Digestion" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 84: Apical squamous epithelium - Cornification" 11 "Plasma membrane" "HPA030783: , HPA056418: " "unprognostic (5.86e-3)" "potential prognostic unfavorable (7.14e-4)" "unprognostic (5.41e-3)" "unprognostic (9.27e-3)" "unprognostic (1.61e-1)" "unprognostic (4.75e-2)" "unprognostic (9.31e-2)" "unprognostic (3.31e-2)" "potential prognostic unfavorable (3.38e-5)" "unprognostic (5.27e-2)" "unprognostic (5.44e-3)" "unprognostic (1.45e-1)" "unprognostic (4.36e-3)" "unprognostic (7.08e-2)" "unprognostic (2.68e-2)" "unprognostic (3.79e-2)" "unprognostic (2.02e-1)" "unprognostic (2.42e-1)" "potential prognostic unfavorable (3.08e-5)" "unprognostic (2.00e-2)" "unprognostic (2.18e-2)" "unprognostic (1.52e-2)" "unprognostic (8.66e-2)" "unprognostic (1.33e-2)" "unprognostic (1.23e-1)" "unprognostic (7.98e-2)" "unprognostic (3.01e-1)" PSD "EFA6, EFA6A, KIAA2011, PSD1, TYL" ENSG00000059915 "Pleckstrin and Sec7 domain containing" A5PKW4 10 102402617-102421539 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 475.5;intestine: 249.1" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 55.4;Cardiomyocytes: 108.4;Cone photoreceptor cells: 111.8;Corticotrophs: 65.9;Epicardial cells: 106.9;Gonadotrophs: 66.2;Lactotrophs: 101.5;Pancreatic islet cells: 53.4;Retinal bipolar cells: 91.7;Rod photoreceptor cells: 158.6;Smooth muscle cells: 146.5;Somatotrophs: 66.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 16.3" "Adrenal gland - Adrenal medulla cells, Pancreas - Alpha cells, Pituitary gland - Lactotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059237 Uncertain NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 79: Photoreceptor cells - Phototransduction" "HPA059237: " "unprognostic (1.75e-2)" "unprognostic (1.68e-1)" "unprognostic (1.19e-1)" "unprognostic (1.38e-2)" "unprognostic (1.22e-2)" "unprognostic (2.15e-2)" "unprognostic (1.63e-2)" "potential prognostic favorable (2.01e-4)" "unprognostic (1.61e-1)" "unprognostic (3.87e-2)" "unprognostic (4.36e-1)" "unprognostic (2.54e-1)" "unprognostic (1.86e-1)" "unprognostic (3.11e-1)" "unprognostic (8.02e-2)" "unprognostic (1.37e-1)" "potential prognostic favorable (8.40e-4)" "unprognostic (5.75e-2)" "unprognostic (3.47e-2)" "unprognostic (5.33e-2)" "unprognostic (2.23e-2)" "unprognostic (1.57e-1)" "unprognostic (7.46e-3)" "unprognostic (1.34e-1)" "unprognostic (8.76e-2)" "unprognostic (3.17e-1)" PSD2 "DKFZp761B0514, EFA6C" ENSG00000146005 "Pleckstrin and Sec7 domain containing 2" Q9BQI7 5 139795808-139844466 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "brain: 81.6" "Group enriched" "Detected in some" 9 "Astrocytes: 253.2;Bergmann glia: 123.6;Ependymal cells: 127.5;Oligodendrocyte progenitor cells: 66.4" "Cell type enhanced" "Detected in all" "astrocyte: 321.9;Bergmann glia: 135.9;ependymal cell: 139.6" "Cancer enriched" "Detected in single" 45 "Glioblastoma Multiforme (TCGA): 30.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 2.2;Neuroblastoma: 1.6" "Colon - Enteric glia cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054625 Approved "Plasma membrane" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 28: Astrocytes - Homeostasis & neuron support" "Plasma membrane" "HPA054625: " "unprognostic (2.68e-2)" "unprognostic (2.79e-2)" "unprognostic (1.39e-1)" PSD3 "DKFZp761K1423, EFA6D, EFA6R, HCA67, KIAA0942" ENSG00000156011 "Pleckstrin and Sec7 domain containing 3" Q9NYI0 8 18527303-19084730 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 65.1" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 1567.7;Bergmann glia: 1487.7;Cardiomyocytes: 1236.3;Early spermatids: 1018.4;Foveolar cells: 965.5;Somatotrophs: 1346.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Cardiomyocytes, Skeletal muscle - Fibroblasts, Spleen - Endothelial cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002455 Enhanced Approved "Nucleoplasm,Vesicles,Cytosol,Calyx,Mid piece,Principal piece,End piece" Yes No "Cluster 24: Non-specific - Transcription" "Cluster 27: Cerebellum - Synaptic function" "Cluster 34: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 18: Adrenal cortex cells - Steroidogensis" 7 "Nucleoplasm, Vesicles" "Cytosol, Calyx, Mid piece, Principal piece, End piece" "HPA002455: " "unprognostic (8.40e-3)" "unprognostic (9.64e-2)" "unprognostic (5.49e-2)" "unprognostic (4.45e-1)" "unprognostic (2.72e-2)" "unprognostic (2.01e-2)" "unprognostic (3.46e-1)" "potential prognostic favorable (7.69e-4)" "unprognostic (4.67e-2)" "potential prognostic unfavorable (1.28e-5)" "unprognostic (1.02e-2)" "unprognostic (7.55e-2)" "unprognostic (7.10e-2)" "unprognostic (6.56e-3)" "unprognostic (3.31e-2)" "unprognostic (1.20e-1)" "unprognostic (1.07e-3)" "unprognostic (1.28e-1)" "unprognostic (1.84e-2)" "unprognostic (2.98e-1)" "unprognostic (1.25e-2)" "unprognostic (5.49e-2)" "unprognostic (1.13e-2)" "unprognostic (3.97e-2)" "unprognostic (1.92e-1)" "unprognostic (9.27e-3)" "unprognostic (1.45e-1)" "unprognostic (4.62e-2)" "unprognostic (2.36e-1)" "unprognostic (8.19e-2)" "unprognostic (2.24e-2)" PSD4 "EFA6B, TIC" ENSG00000125637 "Pleckstrin and Sec7 domain containing 4" Q8NDX1 2 113157325-113209396 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hepatocytes: 74.6;Neutrophils: 83.3;Prostatic glandular cells: 65.6" "Cell type enhanced" "Detected in many" "leukocyte: 53.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Breast - Breast glandular cells, Colon - T-cells, Prostate - Prostate glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in single" "HPA034722, HPA077847" Enhanced NA NA "Cluster 24: Non-specific - Transcription" "Cluster 70: Non-specific - Protein processing" "Cluster 51: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 51: Secretory epithelial cells - Mixed function" 2 "HPA034722: , HPA077847: " "unprognostic (2.27e-1)" "unprognostic (3.87e-2)" "unprognostic (2.15e-3)" "unprognostic (1.11e-3)" "unprognostic (3.98e-1)" "unprognostic (1.31e-1)" "unprognostic (7.03e-2)" "unprognostic (1.22e-2)" "unprognostic (3.42e-2)" "unprognostic (7.27e-3)" "unprognostic (2.57e-2)" "unprognostic (4.63e-2)" "unprognostic (4.25e-3)" "unprognostic (2.35e-3)" "unprognostic (2.17e-1)" "unprognostic (1.51e-2)" "unprognostic (2.98e-1)" "unprognostic (2.21e-2)" "unprognostic (1.75e-1)" "unprognostic (1.96e-2)" "unprognostic (1.17e-2)" "unprognostic (7.52e-3)" "unprognostic (9.18e-2)" "unprognostic (1.06e-1)" "unprognostic (1.17e-1)" "unprognostic (7.99e-2)" "potential prognostic favorable (2.63e-4)" "unprognostic (2.37e-1)" "unprognostic (1.29e-2)" "unprognostic (6.40e-2)" PSEN1 "AD3, FAD, PS1, S182" ENSG00000080815 "Presenilin 1" P49768 14 73136418-73223691 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Cell adhesion, Notch signaling pathway" "Hydrolase, Protease" "Alzheimer disease, Amyloidosis, Cancer-related genes, Cardiomyopathy, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 479.8;Neutrophil progenitors: 647.4;Neutrophils: 2031.4;Oligodendrocytes: 545.2" "Cell type enhanced" "Detected in all" "oligodendrocyte: 755.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006844, HPA030760, HPA067496" Approved Supported "Nucleoplasm,Golgi apparatus,Cell Junctions" Yes No "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 63 "Golgi apparatus" "Nucleoplasm, Cell Junctions" "CAB006844: , HPA030760: , HPA067496: " "unprognostic (7.43e-3)" "unprognostic (2.99e-1)" "unprognostic (9.78e-3)" "unprognostic (7.61e-3)" "unprognostic (5.67e-2)" "unprognostic (6.43e-3)" "unprognostic (3.48e-1)" "unprognostic (8.87e-2)" "unprognostic (1.99e-2)" "potential prognostic unfavorable (3.47e-4)" "potential prognostic favorable (3.35e-7)" "unprognostic (1.24e-2)" "unprognostic (1.18e-1)" "potential prognostic unfavorable (2.07e-5)" "unprognostic (9.28e-2)" "unprognostic (1.47e-2)" "unprognostic (2.52e-1)" "unprognostic (4.03e-1)" "unprognostic (1.88e-1)" "unprognostic (9.10e-3)" "unprognostic (1.67e-3)" "unprognostic (2.40e-3)" "unprognostic (1.88e-2)" "unprognostic (2.34e-1)" "unprognostic (3.28e-2)" "unprognostic (9.36e-3)" "unprognostic (2.17e-1)" "unprognostic (8.30e-2)" "unprognostic (3.10e-1)" "unprognostic (4.37e-1)" "unprognostic (3.73e-1)" PSEN2 "AD3L, AD4, PS2, STM2" ENSG00000143801 "Presenilin 2" P49810 1 226870184-226927726 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Notch signaling pathway" "Hydrolase, Protease" "Alzheimer disease, Amyloidosis, Cardiomyopathy, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 7.7;Brain inhibitory neurons: 7.8;Choroid plexus epithelial cells: 7.4;Distal convoluted tubule cells: 6.5;Ependymal cells: 5.4;Loop of henle epithelial cells: 5.6;Microglia: 5.3;Other brain neurons: 12.2;Podocytes: 8.3;Proximal tubule cells: 4.9;Renal collecting duct intercalated cells: 21.1;Renal collecting duct principal cells: 5.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pituitary gland - Gonadotropes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 23: Choroid plexus - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 67 "unprognostic (5.59e-2)" "unprognostic (9.97e-2)" "unprognostic (1.34e-1)" "unprognostic (3.99e-3)" "unprognostic (1.14e-1)" "unprognostic (2.19e-1)" "unprognostic (9.02e-2)" "unprognostic (1.84e-2)" "unprognostic (5.11e-3)" "unprognostic (6.70e-2)" "unprognostic (9.83e-2)" "unprognostic (2.63e-1)" "unprognostic (5.73e-2)" "unprognostic (3.49e-2)" "unprognostic (2.15e-2)" "unprognostic (1.22e-1)" "unprognostic (1.16e-1)" "unprognostic (2.75e-1)" "unprognostic (2.88e-1)" "unprognostic (1.29e-1)" "unprognostic (9.78e-2)" "unprognostic (9.71e-3)" "unprognostic (1.85e-1)" "unprognostic (4.24e-2)" "unprognostic (2.42e-1)" "unprognostic (3.08e-3)" "unprognostic (2.88e-1)" "unprognostic (4.38e-1)" "unprognostic (1.95e-1)" "unprognostic (2.51e-1)" "unprognostic (3.27e-2)" PSENEN PEN2 ENSG00000205155 "Presenilin enhancer, gamma-secretase subunit" Q9NZ42 19 35745600-35747519 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Notch signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 320.3" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 305.2;Epididymal efferent duct ciliated cells: 285.0;Fallopian tube ciliated cells: 428.1;Late primary spermatocytes: 469.2;Late spermatids: 115.0;Respiratory ciliated cells: 212.8" "Cell type enhanced" "Detected in many" "ependymal cell: 28.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047435 Enhanced NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 107: Ciliated cells - Cilia assembly & function" 18 "HPA047435: " "unprognostic (1.55e-1)" "unprognostic (1.54e-1)" "unprognostic (5.31e-2)" "unprognostic (1.89e-1)" "unprognostic (1.03e-1)" "unprognostic (2.98e-1)" "unprognostic (2.50e-1)" "unprognostic (7.83e-2)" "unprognostic (1.47e-2)" "unprognostic (1.36e-1)" "validated prognostic unfavorable (3.10e-5)" "validated prognostic unfavorable (4.94e-6)" "unprognostic (1.77e-1)" "potential prognostic unfavorable (5.95e-5)" "unprognostic (3.52e-2)" "potential prognostic unfavorable (7.03e-4)" "unprognostic (1.08e-1)" "unprognostic (1.74e-1)" "unprognostic (1.53e-2)" "unprognostic (2.08e-2)" "unprognostic (8.40e-2)" "unprognostic (1.69e-2)" "unprognostic (4.64e-1)" "unprognostic (7.15e-2)" "unprognostic (1.49e-2)" "unprognostic (1.86e-1)" "unprognostic (1.93e-1)" "unprognostic (1.16e-1)" "unprognostic (8.39e-3)" "unprognostic (2.14e-1)" "unprognostic (3.57e-1)" PSG1 "CD66f, PBG1, PSBG1, PSGGA" ENSG00000231924 "Pregnancy specific beta-1-glycoprotein 1" P11464 19 42866464-42879822 "CD markers, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 399 "placenta: 245.4" "Cell type enriched" "Detected in some" 23 "Syncytiotrophoblasts: 286.4" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in some" "Thyroid Carcinoma (TCGA): 2.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "thyroid cancer: 173.3" HPA046327 Supported "Secreted in female reproductive system" "No annotated function" NA NA 100000000 "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 72: Neuronal - Signal transduction" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." 1 "HPA046327: " "unprognostic (6.77e-2)" "unprognostic (2.78e-2)" PSG11 "MGC22484, PSG13, PSG14" ENSG00000243130 "Pregnancy specific beta-1-glycoprotein 11" Q9UQ72 19 43007656-43026474 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 88 "placenta: 49.9" "Cell type enriched" "Detected in some" 14 "Syncytiotrophoblasts: 213.2" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 2.5;Rhabdoid: 2.7;testis cancer: 1.8" "HPA042240, HPA046327" Enhanced Approved Vesicles "Secreted in female reproductive system" "No annotated function" NA NA 21000000 "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 72: Neuronal - Signal transduction" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." Vesicles "HPA042240: , HPA046327: " PSG2 "CEA, PSBG2, PSG1, PSGGB" ENSG00000242221 "Pregnancy specific beta-1-glycoprotein 2" P11465 19 43064209-43083045 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 249 "placenta: 225.0" "Cell type enriched" "Detected in some" 20 "Syncytiotrophoblasts: 1085.6" "Low cell type specificity" "Detected in some" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 9.1;testis cancer: 8.7" "Secreted in female reproductive system" "No annotated function" NA NA 30000000 "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 15: Non-specific - Transcription" "Cluster 72: Neuronal - Signal transduction" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." "unprognostic (1.27e-2)" PSG3 ENSG00000221826 "Pregnancy specific beta-1-glycoprotein 3" Q16557 19 42721638-42740481 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 200 "placenta: 133.5" "Cell type enriched" "Detected in some" 87 "Syncytiotrophoblasts: 2112.6" "Low cell type specificity" "Detected in some" "Cancer enriched" "Detected in single" 7 "Lung Adenocarcinoma (TCGA): 1.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney cancer: 2.2;Rhabdoid: 2.9;thyroid cancer: 3.1" HPA046327 Supported "Secreted in female reproductive system" "No annotated function" NA NA 45000000 "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." 5 "HPA046327: " "potential prognostic unfavorable (2.44e-4)" PSG4 ENSG00000243137 "Pregnancy specific beta-1-glycoprotein 4" Q00888 19 43192702-43207299 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 30 "parathyroid gland: 52.3;placenta: 135.5" "Cell type enriched" "Detected in some" 27 "Syncytiotrophoblasts: 732.4" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in many" 5 "Kidney Chromophobe (TCGA): 15.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 68.6" "Pancreas - Ductal cells" HPA046327 Supported "Secreted in female reproductive system" "No annotated function" NA NA 53000000 "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 15: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." 1 "HPA046327: " "unprognostic (1.85e-1)" "unprognostic (1.85e-1)" "unprognostic (3.15e-3)" "unprognostic (3.30e-3)" "unprognostic (2.42e-2)" "unprognostic (1.33e-1)" "unprognostic (1.58e-1)" "unprognostic (1.13e-1)" "unprognostic (6.50e-2)" "unprognostic (1.79e-1)" PSG5 "FL-NCA-3, PSG" ENSG00000204941 "Pregnancy specific beta-1-glycoprotein 5" Q15238 19 43166256-43186536 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 127 "placenta: 105.5" "Cell type enriched" "Detected in some" 16 "Syncytiotrophoblasts: 1020.0" "Low cell type specificity" "Detected in single" "Cancer enriched" "Detected in some" 6 "Kidney Chromophobe (TCGA): 13.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Pancreas - Ductal cells" HPA046327 Supported "Secreted in female reproductive system" "No annotated function" NA NA 18000000 "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 15: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." 1 "HPA046327: " "unprognostic (4.54e-2)" "unprognostic (4.51e-2)" "unprognostic (1.78e-1)" "unprognostic (9.06e-2)" "unprognostic (7.27e-2)" PSG6 ENSG00000170848 "Pregnancy specific beta-1-glycoprotein 6" Q00889 19 42902086-42919563 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 35 "placenta: 46.7" "Cell type enriched" "Detected in some" 66 "Syncytiotrophoblasts: 592.1" "Low cell type specificity" "Detected in some" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Sarcoma: 9.6;testis cancer: 3.6" HPA046327 Supported "Secreted in female reproductive system" "No annotated function" NA NA 49000000 "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 15: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." "HPA046327: " "potential prognostic favorable (2.10e-4)" PSG7 ENSG00000221878 "Pregnancy specific beta-1-glycoprotein 7" Q13046 19 42924132-42937207 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Group enriched" "Detected in some" 4 "placenta: 3.9;skin 1: 1.1" "Cell type enriched" "Detected in some" 22 "Syncytiotrophoblasts: 174.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Rhabdoid: 6.5" "Skin - Keratinocyte (granular)" HPA046327 Supported "Secreted in female reproductive system" "No annotated function" NA NA 45000000 "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 15: Non-specific - Transcription" "Cluster 72: Neuronal - Signal transduction" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." "HPA046327: " PSG8 ENSG00000124467 "Pregnancy specific beta-1-glycoprotein 8" Q9UQ74 19 42752686-42765678 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 24 "placenta: 6.1" "Cell type enriched" "Detected in some" 6 "Syncytiotrophoblasts: 70.5" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in single" 15 "Thyroid Carcinoma (TCGA): 2.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 2.0;Rhabdoid: 1.7" "Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Gonadotropes, Testis - Late spermatids" HPA046327 Supported "Secreted in female reproductive system" "No annotated function" NA NA 21000000 "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." "HPA046327: " "unprognostic (8.87e-2)" PSG9 "PSG11, PSGII" ENSG00000183668 "Pregnancy specific beta-1-glycoprotein 9" Q00887 19 43211791-43269530 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 137 "placenta: 100.4" "Cell type enriched" "Detected in some" 24 "Syncytiotrophoblasts: 329.1" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in some" 7 "Kidney Chromophobe (TCGA): 7.3" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Bladder cancer: 6.6;breast cancer: 22.3;liver cancer: 7.5;Rhabdoid: 26.1;testis cancer: 9.8" HPA046327 Supported "Secreted in female reproductive system" "No annotated function" NA NA 50000000 "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 15: Non-specific - Transcription" "Cluster 72: Neuronal - Signal transduction" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." "HPA046327: " "unprognostic (6.37e-2)" "unprognostic (2.08e-2)" "unprognostic (1.59e-1)" "unprognostic (1.72e-2)" "unprognostic (2.13e-2)" PSIP1 "DFS70, LEDGF, p52, p75, PSIP2" ENSG00000164985 "PC4 and SFRS1 interacting protein 1" O75475 9 15464066-15510995 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 340.4;Undifferentiated spermatogonia: 325.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013718, HPA019697" Enhanced Enhanced Nucleoplasm NA NA 46000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 65: Brain - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 7: Non-specific - Transcription" 37 Nucleoplasm "CAB013718: , HPA019697: " "unprognostic (6.17e-3)" "unprognostic (2.32e-1)" "unprognostic (4.64e-2)" "unprognostic (1.31e-1)" "unprognostic (3.41e-1)" "unprognostic (2.40e-2)" "unprognostic (1.61e-1)" "unprognostic (1.33e-1)" "unprognostic (1.66e-1)" "unprognostic (1.85e-2)" "potential prognostic favorable (1.42e-4)" "unprognostic (2.23e-3)" "unprognostic (6.96e-2)" "unprognostic (1.98e-3)" "unprognostic (4.36e-2)" "unprognostic (1.05e-1)" "unprognostic (1.11e-2)" "unprognostic (9.79e-2)" "unprognostic (1.50e-2)" "unprognostic (7.71e-2)" "unprognostic (3.29e-2)" "unprognostic (3.83e-2)" "unprognostic (5.66e-2)" "unprognostic (2.53e-2)" "unprognostic (3.20e-2)" "unprognostic (2.02e-1)" "unprognostic (1.58e-2)" "unprognostic (1.37e-1)" "unprognostic (2.12e-1)" "unprognostic (4.10e-1)" "unprognostic (3.54e-1)" PSKH1 ENSG00000159792 "Protein serine kinase H1" P11801 16 67893254-67929676 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 50.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Minor Salivary Gland - Minor salivary glandular cells, Prostate - Smooth muscle cells, Skin - Macrophages, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053927, HPA062763" Approved Supported "Nuclear speckles,Plasma membrane,Primary cilium,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 70: Non-specific - Protein processing" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 4 "Nuclear speckles" "Plasma membrane, Primary cilium, Cytosol" "HPA053927: , HPA062763: " "unprognostic (2.14e-1)" "unprognostic (1.42e-2)" "unprognostic (2.42e-1)" "unprognostic (6.76e-2)" "unprognostic (1.08e-1)" "unprognostic (2.03e-1)" "unprognostic (1.38e-1)" "unprognostic (1.17e-3)" "unprognostic (1.57e-1)" "unprognostic (2.80e-2)" "potential prognostic favorable (7.28e-7)" "unprognostic (3.28e-1)" "potential prognostic favorable (8.05e-6)" "unprognostic (3.08e-2)" "unprognostic (2.18e-2)" "unprognostic (3.27e-2)" "unprognostic (1.29e-1)" "unprognostic (1.99e-2)" "unprognostic (1.08e-1)" "unprognostic (1.49e-1)" "unprognostic (4.26e-2)" "unprognostic (3.59e-2)" "unprognostic (1.26e-3)" "unprognostic (4.44e-2)" "unprognostic (2.68e-1)" "unprognostic (3.25e-2)" "unprognostic (4.22e-1)" "unprognostic (2.45e-1)" "unprognostic (1.12e-1)" "unprognostic (3.58e-3)" "unprognostic (1.84e-1)" PSKH2 ENSG00000147613 "Protein serine kinase H2" Q96QS6 8 86047109-86088621 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 10 "retina: 2.3" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 53.8;Megakaryocyte progenitors: 11.0;Podocytes: 3.4;Renal collecting duct intercalated cells: 7.1;Rod photoreceptor cells: 32.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 1.1;Testicular Germ Cell Tumor (TCGA): 1.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015095, HPA056839" Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 42: Retina - Visual perception" "Cluster 47: Leukemia - Hemostasis" "Cluster 79: Photoreceptor cells - Phototransduction" 14 Nucleoplasm "Nuclear bodies, Cytosol" "HPA015095: , HPA056839: " "unprognostic (1.92e-1)" PSMA1 "HC2, MGC14542, MGC14575, MGC14751, MGC1667, MGC21459, MGC22853, MGC23915, NU, PROS30" ENSG00000129084 "Proteasome 20S subunit alpha 1" P25786 11 14504874-14643635 "Enzymes, Essential proteins, Predicted intracellular proteins" Immunity "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 256.9;Microglia: 375.5;Neutrophils: 181.3" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 468.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033765, HPA037646, HPA043891, CAB079995" Supported Supported "Nucleoplasm,Nuclear bodies,Centrosome" NA NA 11000000 "Cluster 13: Non-specific - Mitochondria" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 24: Non-specific - Unknown function" "Cluster 9: T-cells - Adaptive immunity: Regulation" 284 Nucleoplasm "Nuclear bodies, Centrosome" "CAB033765: , CAB079995: , HPA037646: , HPA043891: " "unprognostic (1.07e-3)" "unprognostic (1.65e-1)" "unprognostic (1.40e-1)" "unprognostic (1.35e-1)" "unprognostic (1.14e-1)" "unprognostic (1.64e-2)" "unprognostic (9.27e-2)" "unprognostic (8.07e-2)" "potential prognostic unfavorable (9.34e-5)" "unprognostic (2.16e-2)" "potential prognostic favorable (1.16e-4)" "unprognostic (1.20e-1)" "unprognostic (1.83e-1)" "potential prognostic unfavorable (3.72e-7)" "unprognostic (9.45e-3)" "potential prognostic unfavorable (8.92e-5)" "unprognostic (6.16e-2)" "unprognostic (4.53e-2)" "unprognostic (1.26e-2)" "unprognostic (2.89e-2)" "unprognostic (3.87e-2)" "unprognostic (6.33e-3)" "unprognostic (2.95e-2)" "unprognostic (4.18e-1)" "unprognostic (1.87e-2)" "unprognostic (1.75e-3)" "unprognostic (2.78e-1)" "unprognostic (2.14e-1)" "unprognostic (1.03e-1)" "unprognostic (7.30e-2)" "unprognostic (1.44e-1)" PSMA2 "HC3, MU, PMSA2" ENSG00000106588 "Proteasome 20S subunit alpha 2" P25787 7 42916828-42932185 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 4.0;Bergmann glia: 7.4;Brain excitatory neurons: 7.1;Brain inhibitory neurons: 5.2;Ependymal cells: 5.5;Microglia: 4.2;Oligodendrocyte progenitor cells: 7.4;Oligodendrocytes: 10.7;Other brain neurons: 9.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008188 Uncertain NA NA 8600000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 21: Non-specific - Metabolism" "Cluster 67: Non-specific - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" 185 "HPA008188: " "unprognostic (3.10e-3)" "unprognostic (2.07e-3)" "unprognostic (1.89e-1)" "unprognostic (3.02e-3)" "unprognostic (2.44e-1)" "unprognostic (1.43e-2)" "unprognostic (1.39e-3)" "unprognostic (4.02e-1)" "potential prognostic unfavorable (3.46e-4)" "unprognostic (4.21e-3)" "potential prognostic favorable (1.36e-5)" "unprognostic (1.69e-2)" "unprognostic (1.65e-1)" "potential prognostic unfavorable (3.30e-4)" "unprognostic (4.27e-3)" "potential prognostic unfavorable (2.08e-5)" "unprognostic (7.33e-3)" "unprognostic (8.31e-3)" "unprognostic (7.56e-2)" "unprognostic (3.30e-1)" "unprognostic (1.44e-1)" "potential prognostic unfavorable (1.09e-4)" "unprognostic (3.79e-2)" "unprognostic (2.32e-1)" "unprognostic (7.17e-2)" "unprognostic (2.03e-1)" "unprognostic (2.97e-1)" "unprognostic (1.65e-1)" "unprognostic (1.43e-1)" "unprognostic (4.22e-1)" "unprognostic (2.76e-1)" PSMA3 HC8 ENSG00000100567 "Proteasome 20S subunit alpha 3" P25788 14 58244843-58272012 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 469.6;Migrating cytotrophoblasts: 426.7;Oocytes: 442.1;Syncytiotrophoblasts: 493.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000905 Approved NA NA 10000000 "Cluster 13: Non-specific - Mitochondria" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 177 "HPA000905: " "unprognostic (2.96e-2)" "unprognostic (8.92e-2)" "unprognostic (1.07e-1)" "unprognostic (1.44e-2)" "unprognostic (5.60e-2)" "unprognostic (2.82e-2)" "unprognostic (4.38e-2)" "unprognostic (1.26e-2)" "unprognostic (1.16e-2)" "unprognostic (1.10e-1)" "potential prognostic favorable (5.36e-4)" "unprognostic (1.59e-1)" "unprognostic (8.84e-3)" "potential prognostic unfavorable (2.41e-5)" "unprognostic (1.38e-1)" "potential prognostic unfavorable (1.54e-4)" "unprognostic (6.56e-2)" "unprognostic (1.05e-2)" "unprognostic (1.25e-1)" "unprognostic (5.46e-2)" "unprognostic (1.01e-2)" "unprognostic (1.39e-3)" "unprognostic (8.06e-2)" "unprognostic (1.27e-1)" "unprognostic (1.55e-1)" "unprognostic (9.30e-2)" "unprognostic (1.67e-1)" "unprognostic (1.25e-1)" "unprognostic (2.04e-1)" "unprognostic (6.30e-3)" "unprognostic (2.33e-1)" PSMA4 "HC9, HsT17706" ENSG00000041357 "Proteasome 20S subunit alpha 4" P25789 15 78540405-78552417 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 555.5;Early spermatids: 693.2;Extravillous trophoblasts: 536.3;Late primary spermatocytes: 722.1;Migrating cytotrophoblasts: 538.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004973, HPA055466, HPA060613" Supported Supported "Nucleoplasm,Vesicles,Cytosol,Connecting piece,Flagellar centriole,Mid piece" No No 8300000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 170 "Nucleoplasm, Cytosol" "Vesicles, Connecting piece, Flagellar centriole, Mid piece" "CAB004973: , HPA055466: , HPA060613: " "unprognostic (1.02e-1)" "unprognostic (7.49e-2)" "unprognostic (2.22e-1)" "unprognostic (5.95e-2)" "unprognostic (1.72e-1)" "unprognostic (8.71e-2)" "unprognostic (1.78e-1)" "unprognostic (1.32e-2)" "potential prognostic unfavorable (7.52e-4)" "unprognostic (1.21e-2)" "unprognostic (2.10e-1)" "unprognostic (1.17e-1)" "potential prognostic unfavorable (9.88e-4)" "unprognostic (1.99e-2)" "potential prognostic unfavorable (5.30e-5)" "potential prognostic unfavorable (8.55e-5)" "unprognostic (1.21e-2)" "potential prognostic favorable (8.10e-4)" "unprognostic (9.62e-2)" "unprognostic (2.16e-3)" "unprognostic (2.83e-2)" "potential prognostic unfavorable (4.80e-4)" "unprognostic (1.64e-1)" "unprognostic (5.72e-2)" "unprognostic (8.96e-2)" "unprognostic (7.04e-2)" "unprognostic (3.32e-3)" "unprognostic (1.36e-1)" "unprognostic (1.25e-1)" "unprognostic (9.35e-2)" "unprognostic (7.05e-3)" PSMA5 ZETA ENSG00000143106 "Proteasome 20S subunit alpha 5" P28066 1 109399042-109426448 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028392, HPA028398, HPA028441" Approved Supported Cytosol NA NA 13000000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 37: Non-specific - mRNA processing" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 175 Cytosol "HPA028392: , HPA028398: , HPA028441: " "unprognostic (1.78e-2)" "unprognostic (2.97e-1)" "unprognostic (2.45e-2)" "unprognostic (3.23e-1)" "unprognostic (2.25e-3)" "unprognostic (2.12e-3)" "unprognostic (3.28e-1)" "unprognostic (1.39e-2)" "unprognostic (2.09e-1)" "unprognostic (2.59e-1)" "potential prognostic favorable (3.41e-5)" "unprognostic (1.98e-1)" "unprognostic (4.11e-2)" "unprognostic (2.60e-1)" "potential prognostic unfavorable (4.81e-4)" "unprognostic (2.50e-1)" "unprognostic (4.77e-2)" "unprognostic (1.07e-1)" "unprognostic (1.41e-1)" "unprognostic (2.27e-1)" "unprognostic (1.22e-1)" "unprognostic (2.59e-1)" "unprognostic (2.89e-1)" "unprognostic (2.70e-1)" "unprognostic (8.72e-3)" "unprognostic (1.52e-1)" "unprognostic (1.07e-1)" "unprognostic (8.58e-2)" "unprognostic (5.33e-2)" "unprognostic (2.59e-1)" "unprognostic (1.72e-1)" PSMA6 "IOTA, MGC22756, MGC2333, MGC23846, p27K, PROS27" ENSG00000100902 "Proteasome 20S subunit alpha 6" P60900 14 35278633-35317493 "Enzymes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Astrocytes: 34.5;Bergmann glia: 36.1;Brain excitatory neurons: 48.7;Brain inhibitory neurons: 48.4;Choroid plexus epithelial cells: 46.4;Ependymal cells: 25.7;Microglia: 45.3;Oligodendrocyte progenitor cells: 41.6;Oligodendrocytes: 47.4;Other brain neurons: 57.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003049 Approved Supported "Nucleoplasm,Primary cilium,Primary cilium tip,Cytosol,Perinuclear theca,Calyx,Connecting piece,Flagellar centriole,Mid piece,End piece" NA NA 15000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 39: Testis - Nuclear processes" "Cluster 21: Non-specific - Metabolism" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 22: Non-specific - Basic cellular functions" 156 Nucleoplasm "Primary cilium, Primary cilium tip, Cytosol, Perinuclear theca, Calyx, Connecting piece, Flagellar centriole, Mid piece, End piece" "HPA003049: " "unprognostic (1.96e-1)" "unprognostic (3.24e-2)" "unprognostic (1.92e-1)" "unprognostic (5.46e-2)" "unprognostic (6.60e-3)" "unprognostic (1.85e-1)" "unprognostic (1.71e-1)" "potential prognostic favorable (4.58e-4)" "unprognostic (1.61e-2)" "unprognostic (1.11e-2)" "potential prognostic favorable (7.65e-4)" "unprognostic (9.38e-2)" "unprognostic (1.19e-1)" "unprognostic (9.32e-3)" "potential prognostic unfavorable (5.36e-4)" "unprognostic (1.04e-2)" "unprognostic (1.15e-2)" "unprognostic (1.19e-1)" "unprognostic (1.65e-1)" "unprognostic (1.66e-2)" "unprognostic (8.95e-2)" "potential prognostic unfavorable (3.47e-4)" "unprognostic (6.34e-2)" "unprognostic (4.07e-2)" "unprognostic (1.65e-1)" "unprognostic (1.94e-2)" "unprognostic (2.15e-1)" "unprognostic (2.39e-1)" "unprognostic (3.93e-1)" "unprognostic (4.63e-2)" "unprognostic (4.38e-2)" PSMA7 "C6, HSPC, RC6-1, XAPC7" ENSG00000101182 "Proteasome 20S subunit alpha 7" O14818 20 62136733-62143440 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 740.0" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 1107.4;Esophageal suprabasal cells: 1124.1;Gastric progenitor cells: 1353.4;Syncytiotrophoblasts: 1048.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046007, CAB046008, HPA047266, HPA071263" Approved Uncertain "Vesicles,Principal piece" NA NA 15000000 "Cluster 29: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 160 "Vesicles, Principal piece" "CAB046007: , CAB046008: , HPA047266: , HPA071263: " "unprognostic (1.42e-1)" "unprognostic (2.38e-3)" "unprognostic (5.26e-3)" "unprognostic (1.44e-1)" "unprognostic (1.62e-1)" "unprognostic (1.28e-1)" "unprognostic (9.51e-2)" "unprognostic (4.97e-2)" "unprognostic (2.91e-3)" "unprognostic (1.52e-3)" "potential prognostic favorable (3.53e-4)" "potential prognostic unfavorable (7.71e-4)" "unprognostic (1.57e-1)" "validated prognostic unfavorable (9.41e-6)" "validated prognostic unfavorable (5.26e-4)" "unprognostic (1.05e-1)" "unprognostic (1.73e-2)" "unprognostic (1.34e-1)" "unprognostic (1.70e-1)" "unprognostic (1.19e-1)" "unprognostic (1.41e-1)" "unprognostic (2.84e-2)" "unprognostic (1.06e-2)" "unprognostic (1.06e-1)" "unprognostic (1.82e-2)" "unprognostic (4.01e-3)" "unprognostic (4.12e-2)" "unprognostic (1.90e-1)" "unprognostic (1.94e-1)" "unprognostic (2.04e-1)" "unprognostic (5.52e-2)" PSMA8 "MGC26605, PSMA7L" ENSG00000154611 "Proteasome 20S subunit alpha 8" Q8TAA3 18 26133852-26193355 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "testis: 15.8" "Group enriched" "Detected in some" 6 "Early primary spermatocytes: 288.2;Late primary spermatocytes: 126.2" "Low cell type specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 7 "Gallbladder cancer: 3.6;lymphoma: 6.9;Myeloma: 3.9" "Testis - Early spermatids, Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA071263 Uncertain "Vesicles,Principal piece" NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 57: Testis - Spermatogenesis" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 3: Early primary spermatocytes - Early meiosis" 21 "Vesicles, Principal piece" "HPA071263: " PSMB1 "HC5, PMSB1" ENSG00000008018 "Proteasome 20S subunit beta 1" P20618 6 170535120-170553307 "Enzymes, Essential proteins, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Deafness, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 1014.3;Extravillous trophoblasts: 982.7;Migrating cytotrophoblasts: 913.9;Syncytiotrophoblasts: 1444.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029635, HPA029637, CAB033911" Enhanced Supported Nucleoplasm NA NA 7200000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 28: Non-specific - Nuclear processes" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 253 Nucleoplasm "CAB033911: , HPA029635: , HPA029637: " "potential prognostic unfavorable (2.99e-4)" "potential prognostic unfavorable (2.34e-5)" "unprognostic (2.91e-2)" "unprognostic (1.11e-1)" "unprognostic (7.33e-2)" "unprognostic (3.44e-2)" "unprognostic (5.54e-2)" "unprognostic (5.60e-1)" "unprognostic (1.23e-3)" "unprognostic (5.21e-2)" "unprognostic (2.15e-1)" "unprognostic (3.15e-1)" "unprognostic (1.80e-2)" "unprognostic (9.48e-3)" "potential prognostic unfavorable (1.02e-4)" "potential prognostic unfavorable (5.40e-4)" "unprognostic (1.84e-2)" "unprognostic (2.94e-3)" "unprognostic (1.35e-1)" "unprognostic (4.61e-2)" "unprognostic (4.30e-1)" "unprognostic (1.09e-1)" "unprognostic (1.99e-1)" "unprognostic (2.69e-2)" "unprognostic (4.06e-2)" "unprognostic (1.32e-1)" "unprognostic (1.96e-1)" "unprognostic (3.72e-1)" "unprognostic (2.28e-2)" "unprognostic (9.09e-3)" "unprognostic (2.26e-1)" PSMB10 "beta2i, LMP10, MECL1, MGC1665" ENSG00000205220 "Proteasome 20S subunit beta 10" P40306 16 67934506-67936864 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Hydrolase, Protease, Threonine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 136.3" "Cell type enhanced" "Detected in many" "Endometrial secretory cells: 11.0;Foveolar cells: 5.0;Monocyte progenitors: 5.9;monocytes: 4.4;NK-cells: 4.3" "Cell type enhanced" "Detected in some" "leukocyte: 4.9;pericyte: 4.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030224, HPA030225, CAB034384, CAB080377" Enhanced Approved Vesicles,Cytosol NA NA 870000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 5: Spleen - Immune response" "Cluster 22: Non-specific - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 27 "Vesicles, Cytosol" "CAB034384: , CAB080377: , HPA030224: , HPA030225: " "unprognostic (3.33e-1)" "unprognostic (8.71e-3)" "unprognostic (3.72e-2)" "unprognostic (6.77e-3)" "unprognostic (1.96e-1)" "unprognostic (1.21e-2)" "unprognostic (1.64e-1)" "unprognostic (3.51e-2)" "unprognostic (6.10e-3)" "unprognostic (1.43e-2)" "unprognostic (3.90e-2)" "unprognostic (1.20e-1)" "unprognostic (1.11e-2)" "unprognostic (1.64e-2)" "unprognostic (8.08e-3)" "unprognostic (1.54e-1)" "unprognostic (1.68e-1)" "unprognostic (2.74e-2)" "unprognostic (1.38e-2)" "unprognostic (2.52e-1)" "unprognostic (2.81e-2)" "unprognostic (3.43e-2)" "unprognostic (1.02e-1)" "unprognostic (1.56e-1)" "unprognostic (1.10e-1)" "unprognostic (1.01e-1)" "unprognostic (3.36e-2)" "unprognostic (1.24e-2)" "unprognostic (2.15e-2)" "unprognostic (4.84e-3)" "unprognostic (1.66e-1)" PSMB11 beta5t ENSG00000222028 "Proteasome subunit beta 11" A5LHX3 14 23042212-23044060 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Threonine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 83 "lymphoid tissue: 28.5" "Group enriched" "Detected in some" 11 "Early spermatids: 1.3;Late primary spermatocytes: 2.6;Late spermatids: 3.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in single" 7 "olfactory bulb: 1.9" "Not detected" "Not detected" "HPA028967, HPA056970" Enhanced NA NA "Cluster 80: Thymus - Adaptive immune response" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 5 "HPA028967: , HPA056970: " PSMB2 HC7-I ENSG00000126067 "Proteasome 20S subunit beta 2" P49721 1 35599541-35641526 "Enzymes, Essential proteins, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 483.9;Extravillous trophoblasts: 396.7;Migrating cytotrophoblasts: 450.1;Syncytiotrophoblasts: 529.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026322, HPA026324" Approved Enhanced Nucleoplasm NA NA 6100000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 37: Non-specific - mRNA processing" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 154 Nucleoplasm "HPA026322: , HPA026324: " "unprognostic (1.44e-1)" "unprognostic (5.69e-2)" "unprognostic (5.06e-2)" "unprognostic (7.29e-2)" "potential prognostic favorable (6.59e-5)" "unprognostic (1.51e-1)" "unprognostic (1.94e-2)" "unprognostic (4.89e-2)" "unprognostic (8.32e-2)" "unprognostic (1.37e-3)" "unprognostic (6.17e-2)" "unprognostic (3.68e-2)" "unprognostic (3.13e-1)" "potential prognostic unfavorable (2.02e-6)" "unprognostic (1.03e-2)" "potential prognostic unfavorable (7.24e-4)" "unprognostic (2.87e-3)" "unprognostic (1.02e-1)" "unprognostic (2.57e-1)" "unprognostic (4.36e-2)" "unprognostic (3.49e-2)" "unprognostic (2.67e-2)" "unprognostic (1.86e-1)" "unprognostic (7.02e-2)" "unprognostic (1.31e-1)" "unprognostic (1.27e-1)" "unprognostic (7.93e-2)" "unprognostic (4.50e-2)" "unprognostic (1.91e-1)" "unprognostic (1.55e-1)" "unprognostic (1.81e-2)" PSMB3 "HC10-II, MGC4147" ENSG00000277791 "Proteasome 20S subunit beta 3" P49720 17 38752741-38764225 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 483.1;Esophageal suprabasal cells: 434.2;Extravillous trophoblasts: 486.7;Gastric progenitor cells: 778.0;Hofbauer cells: 452.2;Syncytiotrophoblasts: 531.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042775, HPA048147" Approved NA NA 4200000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 27: Breast cancer - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 151 "HPA042775: , HPA048147: " "unprognostic (3.73e-3)" "unprognostic (4.05e-2)" "unprognostic (2.33e-2)" "unprognostic (1.01e-2)" "unprognostic (7.72e-2)" "unprognostic (8.59e-2)" "unprognostic (2.13e-2)" "unprognostic (1.16e-2)" "unprognostic (5.70e-2)" "potential prognostic unfavorable (2.82e-4)" "unprognostic (1.18e-2)" "unprognostic (2.07e-1)" "unprognostic (1.36e-2)" "potential prognostic unfavorable (8.17e-4)" "unprognostic (5.45e-2)" "unprognostic (3.86e-2)" "unprognostic (3.73e-1)" "unprognostic (1.14e-1)" "unprognostic (3.16e-1)" "unprognostic (2.68e-2)" "unprognostic (1.28e-1)" "unprognostic (8.97e-2)" "unprognostic (5.43e-2)" "unprognostic (2.29e-1)" "unprognostic (2.56e-1)" "unprognostic (1.91e-1)" "unprognostic (4.30e-2)" "unprognostic (2.05e-1)" PSMB4 "HN3, PROS26" ENSG00000159377 "Proteasome 20S subunit beta 4" P28070 1 151399560-151401937 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 321.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006700, HPA073499" Approved Supported Nucleoplasm,Mitochondria NA NA 4700000 "Cluster 13: Non-specific - Mitochondria" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 162 Nucleoplasm Mitochondria "HPA006700: , HPA073499: " "unprognostic (8.92e-3)" "unprognostic (9.84e-2)" "potential prognostic favorable (6.50e-6)" "unprognostic (3.16e-2)" "unprognostic (3.09e-2)" "unprognostic (3.21e-1)" "unprognostic (1.07e-1)" "unprognostic (1.46e-2)" "unprognostic (9.06e-3)" "unprognostic (2.18e-3)" "unprognostic (1.22e-2)" "potential prognostic unfavorable (1.59e-5)" "potential prognostic unfavorable (5.14e-4)" "potential prognostic unfavorable (4.22e-4)" "unprognostic (4.06e-2)" "unprognostic (2.48e-2)" "unprognostic (1.91e-2)" "unprognostic (3.46e-1)" "unprognostic (1.65e-1)" "unprognostic (4.06e-2)" "unprognostic (1.61e-1)" "unprognostic (5.98e-2)" "unprognostic (3.19e-2)" "unprognostic (2.84e-1)" "unprognostic (2.63e-1)" "unprognostic (3.10e-1)" "unprognostic (5.58e-2)" "unprognostic (1.29e-1)" "unprognostic (1.62e-1)" "unprognostic (1.72e-1)" "unprognostic (1.83e-1)" PSMB5 MB1 ENSG00000100804 "Proteasome 20S subunit beta 5" P28074 14 23016543-23035230 "Enzymes, Essential proteins, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Hydrolase, Protease, Threonine protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 476.5;Esophageal apical cells: 416.5;Esophageal basal cells: 490.4;Esophageal suprabasal cells: 539.0;Extravillous trophoblasts: 521.2;Migrating cytotrophoblasts: 470.7;Syncytiotrophoblasts: 483.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049518, HPA061796" Approved Supported "Nucleoplasm,Centrosome,Mid piece,Principal piece" NA NA 4400000 "Cluster 13: Non-specific - Mitochondria" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 97: Non-specific - Cellular respiration" 119 Nucleoplasm "Centrosome, Mid piece, Principal piece" "HPA049518: , HPA061796: " "potential prognostic unfavorable (4.44e-4)" "unprognostic (1.30e-1)" "unprognostic (1.02e-1)" "unprognostic (4.32e-2)" "potential prognostic favorable (9.63e-5)" "unprognostic (3.01e-1)" "unprognostic (1.48e-1)" "unprognostic (1.36e-2)" "potential prognostic unfavorable (2.60e-5)" "unprognostic (2.64e-2)" "unprognostic (3.99e-3)" "unprognostic (2.02e-1)" "unprognostic (3.99e-2)" "validated prognostic unfavorable (7.07e-6)" "validated prognostic unfavorable (2.93e-6)" "unprognostic (2.72e-3)" "potential prognostic unfavorable (2.12e-4)" "unprognostic (3.42e-2)" "unprognostic (2.16e-1)" "potential prognostic favorable (1.02e-4)" "unprognostic (2.91e-1)" "unprognostic (2.07e-1)" "unprognostic (2.57e-1)" "unprognostic (2.22e-1)" "unprognostic (2.46e-1)" "unprognostic (3.98e-2)" "unprognostic (6.57e-2)" "unprognostic (1.10e-1)" "unprognostic (4.09e-2)" "unprognostic (4.30e-1)" "unprognostic (6.98e-3)" PSMB6 "DELTA, Y" ENSG00000142507 "Proteasome 20S subunit beta 6" P28072 17 4796144-4798502 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Hydrolase, Protease, Threonine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 694.1;Esophageal apical cells: 728.5;Esophageal basal cells: 582.2;Esophageal suprabasal cells: 750.6;Migrating cytotrophoblasts: 568.0;Syncytiotrophoblasts: 740.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023312, HPA063656" Supported Supported Nucleoplasm,Mitochondria,Cytosol NA NA 3200000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 105 "Nucleoplasm, Cytosol" Mitochondria "HPA023312: , HPA063656: " "unprognostic (4.43e-3)" "unprognostic (5.40e-2)" "potential prognostic unfavorable (2.58e-4)" "unprognostic (3.00e-3)" "unprognostic (7.40e-2)" "unprognostic (8.18e-2)" "unprognostic (3.20e-2)" "unprognostic (9.82e-2)" "unprognostic (2.46e-2)" "unprognostic (3.33e-3)" "unprognostic (1.08e-1)" "unprognostic (5.37e-2)" "unprognostic (1.26e-3)" "unprognostic (3.13e-2)" "unprognostic (1.92e-1)" "potential prognostic unfavorable (9.82e-5)" "unprognostic (1.57e-1)" "unprognostic (1.22e-1)" "unprognostic (7.62e-2)" "unprognostic (8.51e-3)" "unprognostic (3.45e-1)" "unprognostic (4.57e-2)" "unprognostic (2.39e-1)" "unprognostic (1.77e-1)" "unprognostic (6.07e-2)" "unprognostic (4.31e-1)" "unprognostic (1.93e-1)" "unprognostic (3.11e-2)" "unprognostic (2.06e-1)" "unprognostic (1.47e-2)" "unprognostic (3.10e-2)" PSMB7 Z ENSG00000136930 "Proteasome 20S subunit beta 7" Q99436 9 124353465-124415444 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Hydrolase, Protease, Threonine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 551.5;Late primary spermatocytes: 720.1;Late spermatids: 685.2;Oocytes: 584.8;Syncytiotrophoblasts: 597.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052408, HPA054902" Supported Supported "Nucleoplasm,Nuclear bodies,Primary cilium,Cytosol" No No 5000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 153 Nucleoplasm "Nuclear bodies, Primary cilium, Cytosol" "HPA052408: , HPA054902: " "unprognostic (2.45e-3)" "unprognostic (3.28e-2)" "unprognostic (2.11e-1)" "unprognostic (2.74e-2)" "unprognostic (5.81e-2)" "unprognostic (2.80e-3)" "unprognostic (2.51e-1)" "unprognostic (7.01e-3)" "unprognostic (1.09e-2)" "unprognostic (1.20e-2)" "potential prognostic favorable (1.62e-6)" "unprognostic (1.67e-2)" "unprognostic (4.78e-2)" "unprognostic (2.20e-2)" "unprognostic (2.84e-2)" "potential prognostic unfavorable (2.86e-5)" "unprognostic (2.69e-2)" "unprognostic (1.06e-1)" "unprognostic (8.69e-2)" "unprognostic (1.06e-1)" "unprognostic (3.83e-2)" "unprognostic (9.25e-2)" "unprognostic (1.61e-1)" "unprognostic (3.72e-1)" "unprognostic (3.46e-1)" "unprognostic (1.59e-1)" "unprognostic (6.14e-2)" "unprognostic (2.92e-1)" "unprognostic (6.86e-2)" "unprognostic (5.51e-2)" "unprognostic (3.65e-2)" PSMB8 "beta5i, D6S216E, LMP7, PSMB5i, RING10" ENSG00000204264 "Proteasome 20S subunit beta 8" P28062 6 32840717-32844679 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Host-virus interaction, Immunity" "Hydrolase, Protease, Threonine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast lactating cells: 74.8;Enterocytes: 85.7;Megakaryocytes: 80.4;Platelets: 73.3" "Cell type enhanced" "Detected in many" "endothelial cell: 47.4;leukocyte: 52.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Skeletal muscle - Endothelial cells, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046995, HPA050327" Enhanced Approved "Vesicles,Cytokinetic bridge" Yes No 1900000 "Cluster 25: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 22: Non-specific - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 40 Vesicles "Cytokinetic bridge" "HPA046995: , HPA050327: " "unprognostic (3.53e-1)" "unprognostic (2.98e-2)" "unprognostic (3.40e-1)" "unprognostic (2.90e-1)" "unprognostic (1.15e-1)" "unprognostic (1.17e-1)" "unprognostic (2.94e-2)" "unprognostic (2.43e-1)" "unprognostic (1.09e-1)" "unprognostic (7.61e-3)" "unprognostic (2.13e-1)" "unprognostic (1.39e-1)" "unprognostic (1.82e-1)" "unprognostic (1.81e-1)" "unprognostic (9.03e-3)" "unprognostic (1.07e-2)" "unprognostic (4.11e-2)" "unprognostic (1.35e-1)" "unprognostic (2.15e-2)" "unprognostic (3.81e-2)" "unprognostic (3.36e-3)" "unprognostic (1.47e-3)" "unprognostic (1.02e-1)" "unprognostic (1.08e-1)" "unprognostic (4.76e-3)" "unprognostic (3.53e-2)" "unprognostic (5.29e-2)" "unprognostic (2.11e-1)" "unprognostic (1.71e-1)" "unprognostic (6.62e-3)" "unprognostic (3.57e-2)" PSMB9 "beta1i, LMP2, PSMB6i, RING12" ENSG00000240065 "Proteasome 20S subunit beta 9" P28065 6 32844136-32859851 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Immunity" "Hydrolase, Protease, Threonine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 140.3" "Cell type enhanced" "Detected in many" "cDC: 119.9;Decidual stromal cells: 109.7;Enterocytes: 240.4;Gastric progenitor cells: 215.3;NK-cells: 119.3;pDCs: 117.1;Plasma cells: 107.9;T-cells: 113.7" "Cell type enhanced" "Detected in many" "endothelial cell: 63.9;leukocyte: 99.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Prostate - T-cells, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015180, HPA042818, HPA053280" Enhanced Supported Cytosol NA NA 530000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 5: Spleen - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 39 Cytosol "CAB015180: , HPA042818: , HPA053280: " "unprognostic (2.40e-1)" "unprognostic (2.29e-2)" "unprognostic (2.73e-1)" "unprognostic (3.47e-2)" "unprognostic (8.82e-2)" "unprognostic (1.87e-2)" "unprognostic (3.34e-1)" "unprognostic (7.61e-2)" "unprognostic (1.84e-1)" "unprognostic (2.17e-1)" "unprognostic (1.44e-1)" "unprognostic (6.48e-2)" "unprognostic (4.86e-3)" "unprognostic (1.61e-2)" "unprognostic (1.39e-1)" "unprognostic (4.15e-2)" "unprognostic (6.42e-2)" "unprognostic (4.32e-1)" "unprognostic (3.46e-1)" "unprognostic (7.92e-3)" "potential prognostic favorable (7.28e-4)" "unprognostic (2.00e-3)" "unprognostic (7.15e-2)" "unprognostic (1.14e-1)" "unprognostic (6.32e-2)" "unprognostic (9.85e-3)" "unprognostic (1.24e-1)" "unprognostic (1.56e-1)" "unprognostic (2.15e-1)" "unprognostic (1.03e-2)" "unprognostic (1.54e-1)" PSMC1 "p56, RPT2, S4" ENSG00000100764 "Proteasome 26S subunit, ATPase 1" P62191 14 90256527-90275429 "Essential proteins, Predicted intracellular proteins" "Deafness, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 294.5" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000872, HPA016885" Enhanced Supported Nucleoplasm,Cytosol NA NA 130000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 15: Non-specific - Protein processing" 180 "Nucleoplasm, Cytosol" "HPA000872: , HPA016885: " "potential prognostic unfavorable (6.51e-4)" "unprognostic (2.17e-1)" "unprognostic (9.97e-2)" "unprognostic (8.69e-3)" "unprognostic (1.86e-1)" "unprognostic (9.63e-2)" "unprognostic (1.26e-1)" "unprognostic (4.70e-3)" "potential prognostic unfavorable (1.42e-4)" "unprognostic (1.65e-1)" "potential prognostic favorable (7.62e-4)" "unprognostic (9.61e-2)" "unprognostic (2.69e-2)" "potential prognostic unfavorable (5.60e-6)" "unprognostic (5.60e-2)" "potential prognostic unfavorable (1.10e-4)" "unprognostic (2.88e-2)" "unprognostic (1.31e-2)" "unprognostic (1.69e-1)" "unprognostic (4.88e-2)" "unprognostic (5.39e-3)" "unprognostic (6.33e-2)" "unprognostic (6.48e-2)" "unprognostic (4.23e-1)" "unprognostic (1.35e-1)" "unprognostic (8.73e-2)" "unprognostic (1.07e-1)" "unprognostic (3.63e-1)" "unprognostic (3.47e-1)" "unprognostic (1.97e-1)" "unprognostic (1.18e-1)" PSMC2 "MSS1, Nbla10058, RPT1, S7" ENSG00000161057 "Proteasome 26S subunit, ATPase 2" P35998 7 103328570-103370346 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 288.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019238, HPA049621" Supported Supported "Cytosol,Cytoplasmic bodies" NA NA 220000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 39: Non-specific - Transcription" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 176 "Cytosol, Cytoplasmic bodies" "HPA019238: , HPA049621: " "unprognostic (2.40e-2)" "unprognostic (4.77e-2)" "unprognostic (5.41e-2)" "unprognostic (3.15e-1)" "unprognostic (7.38e-2)" "potential prognostic unfavorable (1.46e-4)" "unprognostic (2.85e-3)" "unprognostic (8.94e-3)" "unprognostic (8.36e-2)" "potential prognostic unfavorable (4.79e-4)" "potential prognostic favorable (2.94e-10)" "unprognostic (1.59e-1)" "unprognostic (4.00e-1)" "unprognostic (7.23e-2)" "unprognostic (1.38e-3)" "unprognostic (4.19e-2)" "unprognostic (1.34e-1)" "unprognostic (1.35e-1)" "unprognostic (4.94e-2)" "unprognostic (2.80e-1)" "unprognostic (7.83e-2)" "unprognostic (2.60e-2)" "unprognostic (1.22e-1)" "unprognostic (9.95e-2)" "unprognostic (5.54e-2)" "unprognostic (3.79e-1)" "unprognostic (1.21e-1)" "unprognostic (3.69e-1)" "unprognostic (1.14e-1)" "unprognostic (4.99e-2)" "unprognostic (5.03e-2)" PSMC3 "RPT5, TBP-1, TBP1" ENSG00000165916 "Proteasome 26S subunit, ATPase 3" P17980 11 47418769-47426473 "Disease related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cataract, Deafness, Intellectual disability, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 315.0;Extravillous trophoblasts: 311.2;Late primary spermatocytes: 330.1;Late spermatids: 321.7;Syncytiotrophoblasts: 439.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006065 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 280000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 202 "Nucleoplasm, Cytosol" "Nuclear bodies" "HPA006065: " "unprognostic (1.12e-3)" "unprognostic (2.58e-2)" "unprognostic (3.76e-2)" "unprognostic (1.15e-1)" "unprognostic (6.41e-2)" "unprognostic (4.22e-1)" "unprognostic (8.75e-2)" "unprognostic (9.60e-2)" "unprognostic (4.77e-2)" "unprognostic (2.82e-3)" "unprognostic (1.53e-1)" "unprognostic (8.06e-2)" "unprognostic (2.54e-3)" "unprognostic (2.82e-3)" "unprognostic (1.20e-2)" "unprognostic (1.01e-3)" "potential prognostic unfavorable (1.19e-5)" "unprognostic (2.81e-2)" "unprognostic (4.83e-2)" "unprognostic (7.16e-2)" "unprognostic (1.14e-1)" "unprognostic (8.27e-3)" "unprognostic (1.39e-1)" "unprognostic (1.04e-1)" "unprognostic (1.49e-1)" "unprognostic (2.91e-1)" "unprognostic (1.21e-1)" "unprognostic (3.65e-1)" "unprognostic (1.23e-1)" "unprognostic (5.38e-2)" "unprognostic (1.28e-1)" PSMC3IP "GT198, Hop2, HUMGT198A, TBPIP" ENSG00000131470 "PSMC3 interacting protein" Q9P2W1 17 42572310-42577831 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA recombination, Meiosis" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 24.3" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 34.6;Early primary spermatocytes: 110.0;Late primary spermatocytes: 70.1;Oocytes: 46.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 2.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA044439 Enhanced Supported Nucleoplasm NA Yes "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 27: Breast cancer - Unknown function" "Cluster 3: Early primary spermatocytes - Early meiosis" 10 Nucleoplasm "HPA044439: " "unprognostic (1.28e-2)" "unprognostic (1.03e-1)" "unprognostic (1.56e-1)" "unprognostic (3.61e-1)" "unprognostic (2.66e-1)" "unprognostic (4.01e-2)" "unprognostic (7.92e-2)" "unprognostic (3.55e-1)" "unprognostic (8.32e-2)" "unprognostic (2.52e-3)" "potential prognostic unfavorable (2.05e-4)" "unprognostic (1.62e-1)" "unprognostic (2.91e-1)" "validated prognostic unfavorable (8.30e-5)" "validated prognostic unfavorable (1.49e-5)" "unprognostic (1.81e-3)" "potential prognostic unfavorable (4.25e-4)" "unprognostic (8.73e-2)" "unprognostic (1.66e-3)" "unprognostic (2.32e-1)" "unprognostic (1.25e-2)" "unprognostic (9.85e-2)" "unprognostic (2.10e-3)" "unprognostic (8.74e-2)" "unprognostic (2.58e-1)" "unprognostic (2.34e-3)" "unprognostic (2.48e-1)" "unprognostic (2.16e-1)" "unprognostic (2.31e-1)" "unprognostic (1.96e-2)" "unprognostic (1.12e-2)" PSMC4 "MGC13687, MGC23214, MGC8570, MIP224, RPT3, S6, TBP-7, TBP7" ENSG00000013275 "Proteasome 26S subunit, ATPase 4" P43686 19 39971165-39981764 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 156.3;Hofbauer cells: 145.7;Late primary spermatocytes: 236.5;Late spermatids: 139.8;Syncytiotrophoblasts: 322.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002044, HPA005471" Approved Supported "Nucleoplasm,Vesicles,Basal body,Cytosol,Mid piece,Principal piece" NA NA 190000 "Cluster 33: Non-specific - ATP binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 191 "Nucleoplasm, Cytosol" "Vesicles, Basal body, Mid piece, Principal piece" "HPA002044: , HPA005471: " "unprognostic (8.02e-2)" "unprognostic (4.04e-1)" "unprognostic (2.30e-1)" "unprognostic (3.31e-2)" "unprognostic (3.53e-3)" "unprognostic (3.58e-2)" "unprognostic (5.19e-1)" "unprognostic (1.98e-1)" "unprognostic (2.68e-3)" "potential prognostic unfavorable (5.25e-4)" "unprognostic (1.60e-2)" "unprognostic (2.19e-3)" "unprognostic (3.64e-1)" "potential prognostic unfavorable (3.16e-5)" "unprognostic (3.61e-3)" "potential prognostic unfavorable (1.04e-5)" "unprognostic (1.18e-1)" "unprognostic (1.26e-1)" "unprognostic (1.83e-1)" "unprognostic (1.08e-1)" "unprognostic (2.90e-1)" "unprognostic (4.11e-2)" "unprognostic (3.14e-1)" "unprognostic (4.33e-1)" "unprognostic (1.85e-1)" "unprognostic (3.65e-1)" "unprognostic (9.69e-3)" "unprognostic (1.40e-1)" "unprognostic (1.27e-1)" "unprognostic (2.03e-1)" "potential prognostic unfavorable (6.89e-5)" PSMC5 "p45, p45/SUG, RPT6, S8, SUG-1, SUG1, TBP10, TRIP1" ENSG00000087191 "Proteasome 26S subunit, ATPase 5" P62195 17 63827152-63832026 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 578.0;Late primary spermatocytes: 496.8;Late spermatids: 2133.5;Oocytes: 455.9;Syncytiotrophoblasts: 459.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017871, HPA064293" Enhanced Supported "Plasma membrane,Cytosol" NA NA 83000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 235 "Plasma membrane, Cytosol" "HPA017871: , HPA064293: " "unprognostic (1.31e-1)" "unprognostic (3.43e-2)" "unprognostic (4.45e-1)" "unprognostic (1.76e-2)" "unprognostic (1.15e-1)" "unprognostic (9.28e-2)" "unprognostic (1.39e-1)" "unprognostic (2.51e-1)" "unprognostic (4.26e-2)" "unprognostic (1.22e-2)" "unprognostic (3.69e-2)" "unprognostic (1.65e-2)" "unprognostic (1.40e-1)" "validated prognostic unfavorable (7.56e-4)" "validated prognostic unfavorable (4.97e-4)" "validated prognostic unfavorable (6.49e-4)" "validated prognostic unfavorable (2.11e-5)" "unprognostic (3.59e-1)" "unprognostic (9.70e-2)" "unprognostic (3.13e-1)" "unprognostic (1.97e-2)" "unprognostic (7.31e-2)" "unprognostic (1.17e-1)" "unprognostic (4.66e-2)" "unprognostic (1.66e-1)" "unprognostic (1.29e-2)" "unprognostic (1.80e-1)" "unprognostic (1.63e-1)" "unprognostic (2.71e-1)" "unprognostic (2.11e-1)" "unprognostic (3.55e-1)" PSMC6 "p42, RPT5" ENSG00000100519 "Proteasome 26S subunit, ATPase 6" P62333 14 52707178-52728590 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 607.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042823 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" No No 230000 "Cluster 25: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 84: Apical squamous epithelium - Cornification" 188 "Nucleoplasm, Cytosol" "Plasma membrane" "HPA042823: " "potential prognostic unfavorable (2.69e-4)" "unprognostic (1.69e-2)" "unprognostic (9.61e-2)" "unprognostic (1.88e-3)" "unprognostic (7.89e-2)" "unprognostic (6.43e-2)" "unprognostic (5.65e-2)" "unprognostic (8.30e-3)" "unprognostic (1.14e-2)" "unprognostic (3.56e-1)" "potential prognostic favorable (4.04e-7)" "unprognostic (1.78e-3)" "unprognostic (3.01e-1)" "potential prognostic unfavorable (3.60e-4)" "unprognostic (1.60e-1)" "potential prognostic unfavorable (1.91e-5)" "unprognostic (9.25e-3)" "unprognostic (3.50e-2)" "unprognostic (3.20e-1)" "unprognostic (2.17e-1)" "unprognostic (2.05e-2)" "unprognostic (9.18e-3)" "unprognostic (1.21e-3)" "unprognostic (3.91e-2)" "unprognostic (1.64e-1)" "unprognostic (4.72e-3)" "unprognostic (1.78e-2)" "unprognostic (1.90e-1)" "unprognostic (5.98e-2)" "unprognostic (3.48e-1)" "unprognostic (1.60e-1)" PSMD1 "P112, Rpn2, S1" ENSG00000173692 "Proteasome 26S subunit, non-ATPase 1" Q99460 2 231056845-231173116 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB021092, HPA036736, HPA036737" Enhanced Approved "Nucleoplasm,Actin filaments" NA NA 290000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 118 Nucleoplasm "Actin filaments" "CAB021092: , HPA036736: , HPA036737: " "unprognostic (5.20e-2)" "unprognostic (2.99e-3)" "unprognostic (1.78e-1)" "unprognostic (9.32e-2)" "unprognostic (1.36e-2)" "unprognostic (1.83e-2)" "unprognostic (1.13e-1)" "unprognostic (4.13e-1)" "unprognostic (7.95e-2)" "unprognostic (8.58e-2)" "potential prognostic favorable (3.29e-5)" "unprognostic (2.68e-1)" "unprognostic (2.79e-2)" "validated prognostic unfavorable (3.12e-7)" "validated prognostic unfavorable (1.87e-4)" "potential prognostic unfavorable (9.78e-5)" "unprognostic (1.82e-2)" "unprognostic (1.39e-1)" "unprognostic (4.32e-1)" "unprognostic (1.38e-1)" "unprognostic (8.70e-2)" "unprognostic (8.03e-3)" "unprognostic (9.48e-2)" "unprognostic (4.69e-1)" "unprognostic (1.60e-3)" "unprognostic (1.22e-1)" "unprognostic (1.40e-1)" "unprognostic (3.54e-2)" "unprognostic (3.34e-1)" "unprognostic (4.69e-1)" "unprognostic (6.39e-2)" PSMD10 p28 ENSG00000101843 "Proteasome 26S subunit, non-ATPase 10" O75832 X 108084207-108091549 "Predicted intracellular proteins" Apoptosis Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 156.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002920, CAB010434" Approved Supported "Primary cilium tip,Cytosol,Perinuclear theca,Calyx,Mid piece,Principal piece" NA NA 190000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 27: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 97: Non-specific - Cellular respiration" 122 "Cytosol, Mid piece" "Primary cilium tip, Perinuclear theca, Calyx, Principal piece" "CAB010434: , HPA002920: " "unprognostic (1.61e-1)" "validated prognostic unfavorable (2.38e-4)" "validated prognostic unfavorable (4.73e-4)" "unprognostic (4.94e-2)" "unprognostic (9.19e-2)" "unprognostic (1.23e-1)" "unprognostic (2.42e-1)" "unprognostic (1.28e-1)" "unprognostic (6.69e-3)" "unprognostic (1.02e-3)" "potential prognostic favorable (3.51e-8)" "unprognostic (1.37e-1)" "unprognostic (1.02e-2)" "unprognostic (3.16e-3)" "potential prognostic unfavorable (8.65e-5)" "unprognostic (2.75e-1)" "potential prognostic unfavorable (1.80e-4)" "unprognostic (8.43e-2)" "unprognostic (3.55e-1)" "unprognostic (3.38e-1)" "unprognostic (1.11e-1)" "unprognostic (3.43e-1)" "unprognostic (1.63e-1)" "unprognostic (3.24e-2)" "unprognostic (8.01e-2)" "unprognostic (3.25e-1)" "unprognostic (1.02e-1)" "unprognostic (5.65e-2)" "unprognostic (3.21e-1)" "unprognostic (3.30e-1)" "unprognostic (1.05e-1)" PSMD11 "MGC3844, p44.5, Rpn6, S9" ENSG00000108671 "Proteasome 26S subunit, non-ATPase 11" O00231 17 32444379-32483319 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 410.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042275, HPA067433" Approved Approved "Nucleoplasm,Golgi apparatus,Perinuclear theca,Principal piece" NA NA 160000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 167 "Nucleoplasm, Golgi apparatus" "Perinuclear theca, Principal piece" "HPA042275: , HPA067433: " "unprognostic (9.23e-2)" "unprognostic (3.47e-3)" "unprognostic (2.01e-1)" "unprognostic (9.50e-2)" "unprognostic (4.84e-2)" "potential prognostic unfavorable (5.57e-4)" "unprognostic (1.69e-1)" "unprognostic (6.08e-2)" "unprognostic (5.42e-3)" "potential prognostic unfavorable (1.17e-4)" "unprognostic (2.92e-3)" "unprognostic (6.85e-2)" "unprognostic (1.37e-2)" "validated prognostic unfavorable (3.33e-5)" "validated prognostic unfavorable (1.22e-4)" "potential prognostic unfavorable (2.25e-5)" "unprognostic (3.76e-2)" "unprognostic (2.62e-2)" "unprognostic (4.32e-2)" "unprognostic (8.89e-2)" "unprognostic (1.32e-1)" "unprognostic (7.17e-3)" "unprognostic (4.32e-3)" "unprognostic (1.07e-1)" "unprognostic (5.99e-3)" "unprognostic (1.12e-2)" "unprognostic (1.16e-1)" "unprognostic (1.42e-1)" "unprognostic (2.56e-1)" "unprognostic (6.11e-2)" "unprognostic (2.42e-1)" PSMD12 "p55, Rpn5" ENSG00000197170 "Proteasome 26S subunit, non-ATPase 12" O00232 17 67337916-67366605 "Disease related genes, Essential proteins, Predicted intracellular proteins" "Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 304.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023119 Approved Approved Nucleoplasm,Microtubules,Cytosol NA NA 88000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 17: Non-specific - RNA processing" 177 Microtubules "Nucleoplasm, Cytosol" "HPA023119: " "unprognostic (1.42e-1)" "unprognostic (6.87e-3)" "unprognostic (1.96e-1)" "unprognostic (4.18e-2)" "unprognostic (5.29e-3)" "unprognostic (4.93e-2)" "unprognostic (2.82e-1)" "unprognostic (5.05e-3)" "unprognostic (2.77e-2)" "potential prognostic unfavorable (2.80e-5)" "unprognostic (2.81e-3)" "unprognostic (2.14e-1)" "unprognostic (3.02e-1)" "potential prognostic unfavorable (3.22e-4)" "unprognostic (7.41e-3)" "unprognostic (3.30e-3)" "unprognostic (4.92e-2)" "unprognostic (9.43e-2)" "unprognostic (5.49e-2)" "unprognostic (1.07e-3)" "unprognostic (1.29e-1)" "unprognostic (3.49e-2)" "unprognostic (2.92e-2)" "potential prognostic unfavorable (2.07e-4)" "unprognostic (9.06e-2)" "unprognostic (4.84e-2)" "unprognostic (2.46e-2)" "unprognostic (7.41e-3)" "unprognostic (4.03e-1)" "unprognostic (4.03e-2)" "unprognostic (2.21e-1)" PSMD13 "p40.5, Rpn9" ENSG00000185627 "Proteasome 26S subunit, non-ATPase 13" Q9UNM6 11 236966-252984 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 249.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038691, HPA038692" Approved Approved "Nuclear speckles,Cytosol" NA NA 240000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 145 "Nuclear speckles" Cytosol "HPA038691: , HPA038692: " "unprognostic (4.87e-3)" "unprognostic (4.46e-2)" "unprognostic (1.02e-3)" "unprognostic (1.74e-2)" "unprognostic (1.03e-1)" "unprognostic (7.60e-2)" "unprognostic (1.89e-1)" "unprognostic (5.75e-3)" "unprognostic (1.33e-3)" "unprognostic (3.01e-2)" "potential prognostic unfavorable (4.34e-4)" "unprognostic (4.32e-2)" "unprognostic (7.09e-2)" "potential prognostic unfavorable (2.30e-6)" "unprognostic (6.37e-3)" "potential prognostic unfavorable (4.64e-4)" "unprognostic (2.48e-3)" "unprognostic (6.11e-2)" "unprognostic (2.52e-1)" "unprognostic (4.86e-1)" "unprognostic (6.66e-2)" "potential prognostic unfavorable (7.46e-4)" "unprognostic (2.92e-3)" "unprognostic (1.95e-1)" "unprognostic (1.10e-1)" "unprognostic (3.02e-1)" "unprognostic (4.06e-1)" "unprognostic (1.24e-1)" "unprognostic (1.09e-1)" "unprognostic (2.66e-1)" "unprognostic (1.80e-1)" PSMD14 "pad1, POH1, Rpn11" ENSG00000115233 "Proteasome 26S subunit, non-ATPase 14" O00487 2 161308425-161411717 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002114, HPA003828" Approved Supported Nucleoplasm NA NA 110000 "Cluster 13: Non-specific - Mitochondria" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 134 Nucleoplasm "HPA002114: , HPA003828: " "potential prognostic unfavorable (4.48e-4)" "potential prognostic unfavorable (1.51e-4)" "unprognostic (8.25e-2)" "unprognostic (1.81e-1)" "unprognostic (1.18e-1)" "unprognostic (1.49e-1)" "unprognostic (6.43e-2)" "unprognostic (3.16e-1)" "unprognostic (9.42e-3)" "unprognostic (5.14e-2)" "unprognostic (4.39e-3)" "unprognostic (4.10e-3)" "potential prognostic unfavorable (4.34e-5)" "validated prognostic unfavorable (1.52e-8)" "validated prognostic unfavorable (3.36e-5)" "potential prognostic unfavorable (2.61e-4)" "unprognostic (3.60e-2)" "unprognostic (1.59e-1)" "unprognostic (3.27e-1)" "unprognostic (5.64e-2)" "unprognostic (5.26e-2)" "unprognostic (1.46e-3)" "unprognostic (7.68e-3)" "unprognostic (3.07e-1)" "unprognostic (1.78e-1)" "unprognostic (6.40e-2)" "unprognostic (1.15e-1)" "unprognostic (1.36e-1)" "unprognostic (3.21e-1)" "unprognostic (2.46e-1)" "unprognostic (1.12e-1)" PSMD2 "MGC14274, P97, Rpn1, S2, TRAP2" ENSG00000175166 "Proteasome 26S subunit ubiquitin receptor, non-ATPase 2" Q13200 3 184299198-184309050 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 300.1" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 271.9;Syncytiotrophoblasts: 289.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045192, HPA062363" Enhanced Approved "Nucleoplasm,Cytokinetic bridge,Centriolar satellite,Cytosol,Flagellar centriole" Yes NA 640000 "Cluster 25: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 223 "Centriolar satellite, Cytosol, Flagellar centriole" "Nucleoplasm, Cytokinetic bridge" "HPA045192: , HPA062363: " "potential prognostic unfavorable (1.69e-5)" "unprognostic (2.98e-3)" "unprognostic (3.66e-1)" "unprognostic (2.15e-2)" "unprognostic (1.49e-1)" "unprognostic (2.30e-1)" "unprognostic (2.54e-1)" "unprognostic (1.24e-2)" "unprognostic (1.69e-2)" "unprognostic (3.72e-3)" "unprognostic (1.24e-3)" "unprognostic (1.07e-3)" "unprognostic (3.21e-2)" "potential prognostic unfavorable (9.10e-6)" "unprognostic (2.06e-3)" "potential prognostic unfavorable (7.45e-5)" "unprognostic (8.53e-3)" "unprognostic (8.00e-3)" "unprognostic (6.97e-3)" "unprognostic (3.95e-1)" "unprognostic (1.41e-2)" "unprognostic (2.41e-3)" "unprognostic (7.64e-2)" "unprognostic (1.67e-1)" "unprognostic (1.41e-1)" "unprognostic (3.58e-1)" "unprognostic (2.66e-1)" "unprognostic (4.12e-1)" "unprognostic (1.69e-1)" "unprognostic (4.06e-2)" "unprognostic (2.64e-1)" PSMD3 "P58, Rpn3, S3, TSTA2" ENSG00000108344 "Proteasome 26S subunit, non-ATPase 3" O43242 17 39980807-39997959 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 242.1" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 195.8;Early spermatids: 286.2;Syncytiotrophoblasts: 331.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017038, HPA048972" Approved Enhanced Nucleoplasm,Cytosol No No 12000000 "Cluster 25: Non-specific - Unknown function" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 14: Neurons - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 209 Nucleoplasm Cytosol "CAB017038: , HPA048972: " "unprognostic (1.17e-1)" "unprognostic (7.33e-2)" "unprognostic (1.86e-1)" "unprognostic (3.33e-2)" "unprognostic (1.37e-1)" "unprognostic (1.02e-2)" "unprognostic (4.25e-2)" "unprognostic (2.89e-2)" "unprognostic (1.49e-3)" "unprognostic (6.60e-3)" "unprognostic (3.58e-2)" "unprognostic (8.85e-2)" "unprognostic (3.90e-2)" "unprognostic (6.44e-3)" "potential prognostic unfavorable (4.19e-6)" "unprognostic (7.71e-3)" "unprognostic (2.18e-2)" "unprognostic (1.76e-1)" "unprognostic (1.09e-3)" "unprognostic (1.55e-1)" "unprognostic (2.26e-1)" "unprognostic (2.81e-1)" "unprognostic (6.90e-2)" "unprognostic (3.78e-2)" "unprognostic (3.98e-2)" "unprognostic (1.46e-3)" "unprognostic (1.58e-2)" "unprognostic (3.96e-1)" "unprognostic (1.94e-1)" "unprognostic (1.21e-1)" "unprognostic (1.18e-1)" PSMD4 "AF, AF-1, Rpn10, S5A" ENSG00000159352 "Proteasome 26S subunit ubiquitin receptor, non-ATPase 4" P55036 1 151254709-151267479 "Cancer-related genes, Essential proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 396.5;Late primary spermatocytes: 534.5;Syncytiotrophoblasts: 505.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038807, HPA039252, CAB047300" Enhanced Approved Nucleoplasm,Cytosol NA NA 52000 "Cluster 25: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 211 Nucleoplasm Cytosol "CAB047300: , HPA038807: , HPA039252: " "unprognostic (1.66e-2)" "unprognostic (4.57e-2)" "unprognostic (8.14e-2)" "unprognostic (1.15e-2)" "unprognostic (3.97e-2)" "unprognostic (2.37e-1)" "unprognostic (9.62e-2)" "unprognostic (2.22e-3)" "unprognostic (2.52e-2)" "unprognostic (3.21e-1)" "potential prognostic unfavorable (8.30e-4)" "unprognostic (1.44e-3)" "potential prognostic unfavorable (4.96e-4)" "unprognostic (7.07e-3)" "unprognostic (9.22e-3)" "unprognostic (1.52e-2)" "unprognostic (3.14e-2)" "unprognostic (2.23e-1)" "unprognostic (2.54e-1)" "unprognostic (1.49e-2)" "unprognostic (5.90e-2)" "unprognostic (1.04e-1)" "unprognostic (7.38e-2)" "unprognostic (2.36e-1)" "unprognostic (6.77e-3)" "unprognostic (9.19e-2)" "unprognostic (2.71e-1)" "unprognostic (1.60e-1)" "unprognostic (3.58e-2)" "unprognostic (2.48e-1)" "unprognostic (4.61e-2)" PSMD5 "KIAA0072, S5B" ENSG00000095261 "Proteasome 26S subunit, non-ATPase 5" Q16401 9 120815496-120842951 "Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003216 Uncertain Approved "Nucleoplasm,Centrosome,Basal body,Cytosol,Connecting piece,Mid piece" No No 230000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 58: Skin - Keratinization" "Cluster 55: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Transcription" 78 "Nucleoplasm, Cytosol" "Centrosome, Basal body, Connecting piece, Mid piece" "HPA003216: " "unprognostic (1.21e-1)" "unprognostic (2.85e-2)" "unprognostic (6.96e-2)" "unprognostic (1.08e-1)" "unprognostic (2.46e-1)" "unprognostic (2.92e-3)" "unprognostic (1.43e-1)" "unprognostic (1.13e-1)" "unprognostic (4.74e-2)" "unprognostic (7.13e-2)" "potential prognostic favorable (2.84e-5)" "unprognostic (3.24e-3)" "unprognostic (1.97e-1)" "unprognostic (2.97e-2)" "unprognostic (7.17e-2)" "unprognostic (5.27e-2)" "unprognostic (3.27e-2)" "unprognostic (5.64e-2)" "unprognostic (1.18e-1)" "unprognostic (3.95e-1)" "unprognostic (3.39e-1)" "unprognostic (2.41e-2)" "unprognostic (2.40e-2)" "unprognostic (2.00e-3)" "unprognostic (3.19e-2)" "unprognostic (1.47e-1)" "unprognostic (3.02e-1)" "unprognostic (1.51e-1)" "unprognostic (1.72e-1)" "unprognostic (2.94e-1)" "unprognostic (2.11e-1)" PSMD6 "KIAA0107, p44S10, Rpn7, S10" ENSG00000163636 "Proteasome 26S subunit, non-ATPase 6" Q15008 3 64010550-64024010 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 269.4" "Cell type enhanced" "Detected in many" "Early spermatids: 501.5;Epicardial cells: 466.2;Late primary spermatocytes: 636.3;Late spermatids: 1259.5;Oocytes: 345.4;Syncytiotrophoblasts: 362.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036921, HPA036922" Uncertain NA NA 97000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 8: Pancreas - Proteolysis" "Cluster 27: Non-specific - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 167 "HPA036921: , HPA036922: " "unprognostic (4.98e-2)" "unprognostic (1.53e-1)" "unprognostic (7.71e-2)" "unprognostic (4.75e-3)" "potential prognostic favorable (7.24e-4)" "unprognostic (1.82e-2)" "unprognostic (2.02e-1)" "unprognostic (7.33e-2)" "unprognostic (3.18e-2)" "unprognostic (1.63e-3)" "potential prognostic favorable (5.22e-5)" "unprognostic (2.65e-1)" "unprognostic (1.39e-2)" "potential prognostic unfavorable (9.56e-5)" "unprognostic (1.17e-3)" "unprognostic (5.13e-3)" "unprognostic (4.12e-3)" "unprognostic (5.01e-2)" "unprognostic (9.51e-2)" "unprognostic (7.26e-3)" "unprognostic (1.90e-2)" "potential prognostic unfavorable (8.34e-4)" "unprognostic (1.07e-1)" "unprognostic (1.90e-1)" "unprognostic (7.34e-2)" "unprognostic (1.40e-1)" "unprognostic (1.03e-1)" "unprognostic (5.29e-2)" "unprognostic (4.42e-1)" "unprognostic (2.93e-1)" "unprognostic (6.57e-3)" PSMD7 "MOV34, P40, Rpn8, S12" ENSG00000103035 "Proteasome 26S subunit, non-ATPase 7" P51665 16 74296814-74306288 "Enzymes, Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 417.4;Esophageal apical cells: 481.9;Syncytiotrophoblasts: 819.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019379, HPA049824, HPA056069" Enhanced Approved "Nucleoplasm,Acrosome,Equatorial segment,Mid piece,Principal piece" NA NA 72000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 124 "Nucleoplasm, Acrosome, Equatorial segment, Mid piece, Principal piece" "CAB019379: , HPA049824: , HPA056069: " "unprognostic (1.75e-3)" "potential prognostic unfavorable (4.09e-4)" "unprognostic (9.46e-3)" "unprognostic (6.38e-3)" "unprognostic (2.43e-1)" "unprognostic (3.31e-1)" "unprognostic (3.29e-1)" "unprognostic (3.41e-1)" "potential prognostic unfavorable (5.02e-4)" "unprognostic (2.83e-2)" "unprognostic (4.32e-2)" "unprognostic (5.14e-2)" "unprognostic (5.48e-2)" "potential prognostic unfavorable (2.31e-4)" "unprognostic (3.78e-3)" "unprognostic (1.16e-3)" "unprognostic (4.45e-2)" "unprognostic (6.23e-2)" "unprognostic (8.14e-2)" "unprognostic (1.94e-1)" "unprognostic (5.39e-2)" "unprognostic (2.73e-2)" "unprognostic (5.30e-3)" "unprognostic (6.42e-3)" "unprognostic (1.03e-1)" "unprognostic (1.61e-1)" "unprognostic (2.53e-1)" "unprognostic (1.51e-2)" "unprognostic (2.88e-1)" "unprognostic (2.41e-2)" "unprognostic (9.45e-2)" PSMD8 "HIP6, HYPF, Nin1p, p31, Rpn12, S14" ENSG00000099341 "Proteasome 26S subunit, non-ATPase 8" P48556 19 38374563-38383850 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 667.0" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 644.1;Late primary spermatocytes: 646.2;Late spermatids: 1824.8;Syncytiotrophoblasts: 665.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006702, CAB021101" Supported Approved "Nuclear speckles,Cytosol" NA NA 71000 "Cluster 33: Non-specific - ATP binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 4: Non-specific - Transcription" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 76 Cytosol "Nuclear speckles" "CAB021101: , HPA006702: " "unprognostic (1.22e-1)" "unprognostic (2.73e-2)" "unprognostic (3.51e-1)" "unprognostic (8.93e-3)" "unprognostic (2.43e-3)" "unprognostic (7.26e-3)" "unprognostic (2.31e-1)" "unprognostic (1.99e-1)" "unprognostic (2.05e-2)" "unprognostic (8.47e-3)" "unprognostic (5.21e-3)" "unprognostic (1.91e-1)" "unprognostic (4.44e-2)" "unprognostic (2.74e-3)" "unprognostic (2.42e-3)" "potential prognostic unfavorable (1.13e-4)" "unprognostic (2.76e-1)" "unprognostic (2.96e-1)" "unprognostic (2.37e-1)" "unprognostic (4.02e-2)" "unprognostic (1.88e-1)" "unprognostic (7.31e-2)" "unprognostic (4.82e-1)" "unprognostic (1.37e-1)" "unprognostic (6.23e-2)" "unprognostic (7.92e-2)" "unprognostic (1.65e-1)" "unprognostic (4.77e-2)" "unprognostic (7.10e-2)" "unprognostic (7.02e-2)" "unprognostic (1.69e-1)" PSMD9 "p27, Rpn4" ENSG00000110801 "Proteasome 26S subunit, non-ATPase 9" O00233 12 121888732-121918297 "Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 15.0;Endometrial secretory cells: 22.0;Gastric chief cells: 38.2;Hepatic stellate cells: 25.8;Parietal cells: 23.0;Suprabasal keratinocytes: 20.0;Tuft cells: 23.1" "Cell type enhanced" "Detected in some" "Bergmann glia: 3.2;pericyte: 2.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040512, HPA044220" Enhanced Supported "Plasma membrane,Cytosol" NA NA 870000 "Cluster 29: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 38: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 63 Cytosol "Plasma membrane" "HPA040512: , HPA044220: " "unprognostic (5.75e-2)" "unprognostic (3.32e-3)" "unprognostic (3.67e-2)" "unprognostic (3.23e-1)" "unprognostic (4.79e-2)" "unprognostic (3.41e-3)" "unprognostic (7.10e-2)" "unprognostic (1.26e-2)" "unprognostic (7.00e-2)" "unprognostic (6.49e-2)" "unprognostic (1.06e-3)" "unprognostic (1.49e-2)" "unprognostic (1.07e-2)" "unprognostic (8.55e-2)" "potential prognostic unfavorable (1.03e-4)" "unprognostic (1.31e-2)" "unprognostic (1.17e-1)" "unprognostic (1.56e-2)" "unprognostic (5.97e-2)" "unprognostic (2.35e-1)" "unprognostic (8.12e-2)" "unprognostic (9.34e-2)" "unprognostic (1.83e-2)" "unprognostic (1.19e-1)" "unprognostic (9.31e-2)" "unprognostic (3.07e-1)" "unprognostic (8.38e-2)" "unprognostic (2.73e-1)" "unprognostic (2.67e-1)" "unprognostic (7.56e-2)" "unprognostic (3.74e-2)" PSME1 "IFI5111, PA28alpha" ENSG00000092010 "Proteasome activator subunit 1" Q06323 14 24136163-24138967 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 402.9;Enterocytes: 541.4;Gastric progenitor cells: 421.7" "Cell type enhanced" "Detected in all" "leukocyte: 69.8;pericyte: 60.8;vascular associated smooth muscle cell: 53.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006632 Approved Approved "Nuclear bodies,Cytosol" NA NA 6500000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Ribosome" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 15: Non-specific - Protein processing" 103 Cytosol "Nuclear bodies" "HPA006632: " "unprognostic (1.07e-1)" "potential prognostic favorable (1.19e-4)" "unprognostic (2.09e-1)" "unprognostic (4.83e-2)" "unprognostic (7.75e-2)" "unprognostic (4.16e-2)" "unprognostic (4.07e-1)" "unprognostic (1.84e-1)" "unprognostic (2.68e-1)" "unprognostic (1.09e-1)" "potential prognostic favorable (4.68e-6)" "unprognostic (3.14e-3)" "unprognostic (2.66e-1)" "unprognostic (1.23e-1)" "unprognostic (2.10e-1)" "unprognostic (1.28e-2)" "unprognostic (2.30e-2)" "unprognostic (2.42e-1)" "unprognostic (3.60e-1)" "unprognostic (8.42e-2)" "unprognostic (1.50e-2)" "potential prognostic unfavorable (8.06e-4)" "unprognostic (2.56e-1)" "unprognostic (1.23e-1)" "unprognostic (4.48e-2)" "unprognostic (2.46e-2)" "unprognostic (2.10e-2)" "unprognostic (1.84e-1)" "unprognostic (6.28e-2)" "potential prognostic favorable (1.95e-4)" "unprognostic (7.10e-2)" PSME2 PA28beta ENSG00000100911 "Proteasome activator subunit 2" Q9UL46 14 24143362-24147570 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 918.5;Esophageal basal cells: 448.9;Esophageal suprabasal cells: 381.1;Gastric progenitor cells: 569.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062661, CAB080614" Approved Approved Nucleoplasm NA NA 2900000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 22: Non-specific - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 65 Nucleoplasm "CAB080614: , HPA062661: " "unprognostic (2.50e-2)" "potential prognostic favorable (3.99e-4)" "unprognostic (2.68e-1)" "unprognostic (1.61e-3)" "unprognostic (1.70e-2)" "unprognostic (1.64e-2)" "unprognostic (2.44e-1)" "unprognostic (7.83e-2)" "unprognostic (1.02e-1)" "unprognostic (1.33e-1)" "potential prognostic unfavorable (7.74e-4)" "unprognostic (4.33e-2)" "unprognostic (2.62e-1)" "unprognostic (5.96e-2)" "unprognostic (1.09e-1)" "unprognostic (6.02e-3)" "unprognostic (8.58e-3)" "unprognostic (3.96e-1)" "unprognostic (1.82e-1)" "unprognostic (4.36e-2)" "potential prognostic favorable (7.51e-4)" "potential prognostic unfavorable (9.81e-4)" "unprognostic (9.95e-2)" "unprognostic (3.66e-1)" "unprognostic (4.30e-2)" "unprognostic (3.66e-2)" "unprognostic (7.31e-3)" "unprognostic (9.73e-2)" "unprognostic (1.84e-1)" "unprognostic (1.00e-2)" "unprognostic (4.29e-2)" PSME3 "Ki, PA28-gamma, PA28G, REG-GAMMA" ENSG00000131467 "Proteasome activator subunit 3" P61289 17 42824385-42843760 "Predicted intracellular proteins" "Apoptosis, Cell cycle, Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 301.4;Late spermatids: 177.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008388, HPA012510" Supported Supported "Nucleoplasm,Primary cilium,Basal body,Cytosol" NA NA 21000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 1: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 184 Nucleoplasm "Primary cilium, Basal body, Cytosol" "CAB008388: , HPA012510: " "unprognostic (1.42e-1)" "unprognostic (8.38e-3)" "unprognostic (2.14e-1)" "unprognostic (2.41e-2)" "unprognostic (4.82e-3)" "unprognostic (8.20e-2)" "unprognostic (1.09e-1)" "unprognostic (1.07e-1)" "unprognostic (2.14e-3)" "potential prognostic unfavorable (5.41e-6)" "potential prognostic favorable (5.08e-5)" "unprognostic (2.90e-1)" "unprognostic (3.02e-2)" "validated prognostic unfavorable (6.60e-4)" "validated prognostic unfavorable (2.18e-4)" "potential prognostic unfavorable (3.73e-4)" "unprognostic (3.72e-3)" "unprognostic (1.47e-1)" "unprognostic (1.37e-1)" "unprognostic (2.69e-2)" "unprognostic (4.95e-3)" "unprognostic (3.10e-2)" "unprognostic (3.34e-1)" "unprognostic (3.56e-2)" "unprognostic (8.87e-2)" "unprognostic (2.65e-2)" "unprognostic (5.29e-3)" "unprognostic (2.99e-1)" "unprognostic (2.83e-2)" "unprognostic (3.25e-2)" "unprognostic (1.91e-1)" PSME3IP1 "C16orf94, FAM192A, NIP30, PIP30" ENSG00000172775 "Proteasome activator subunit 3 interacting protein 1" Q9GZU8 16 57152466-57186116 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 240.8;Late spermatids: 344.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054382, HPA059652" Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 41: Basophils - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Transcription" 53 Nucleoplasm Vesicles "HPA054382: , HPA059652: " "unprognostic (3.41e-2)" "unprognostic (1.70e-2)" "unprognostic (4.84e-2)" "unprognostic (8.60e-3)" "unprognostic (8.87e-2)" "unprognostic (2.29e-1)" "potential prognostic favorable (2.78e-4)" "unprognostic (2.06e-2)" "unprognostic (2.05e-1)" "unprognostic (7.74e-3)" "unprognostic (4.01e-2)" "unprognostic (4.89e-2)" "potential prognostic unfavorable (5.36e-4)" "unprognostic (7.30e-2)" "unprognostic (7.70e-2)" "unprognostic (1.98e-1)" "unprognostic (1.06e-1)" "unprognostic (4.72e-2)" "unprognostic (2.49e-1)" "unprognostic (1.82e-1)" "unprognostic (5.47e-3)" "unprognostic (9.63e-3)" "unprognostic (3.69e-2)" "unprognostic (1.97e-1)" "unprognostic (1.19e-1)" "unprognostic (1.96e-1)" "unprognostic (6.13e-2)" "unprognostic (3.28e-1)" "unprognostic (9.90e-2)" PSME4 "KIAA0077, PA200" ENSG00000068878 "Proteasome activator subunit 4" Q14997 2 53864069-53970993 "Predicted intracellular proteins" "Differentiation, DNA damage, DNA repair, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 53.7" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060922 Approved Supported Nucleoplasm NA NA 19000 "Cluster 32: Basophils - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 95 Nucleoplasm "HPA060922: " "unprognostic (2.09e-2)" "unprognostic (7.74e-3)" "unprognostic (1.04e-1)" "unprognostic (3.83e-1)" "unprognostic (1.34e-1)" "unprognostic (3.48e-2)" "unprognostic (2.05e-2)" "unprognostic (3.05e-1)" "unprognostic (4.24e-2)" "unprognostic (1.90e-1)" "potential prognostic favorable (8.04e-4)" "unprognostic (2.14e-1)" "unprognostic (2.15e-2)" "unprognostic (2.93e-2)" "unprognostic (3.26e-3)" "unprognostic (2.58e-1)" "unprognostic (5.49e-2)" "unprognostic (1.40e-1)" "unprognostic (1.34e-1)" "unprognostic (3.12e-1)" "unprognostic (7.40e-2)" "unprognostic (2.43e-2)" "unprognostic (1.66e-2)" "unprognostic (1.72e-1)" "unprognostic (9.74e-2)" "unprognostic (7.70e-3)" "unprognostic (3.13e-1)" "unprognostic (2.09e-1)" "unprognostic (1.51e-1)" "unprognostic (4.45e-2)" "unprognostic (2.20e-1)" PSMF1 PI31 ENSG00000125818 "Proteasome inhibitor subunit 1" Q92530 20 1113240-1189415 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Late spermatids: 6955.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041122, HPA041300" Approved Enhanced Cytosol NA NA 310000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 62: Non-specific - Plasma proteins" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 67 Cytosol "HPA041122: , HPA041300: " "unprognostic (2.60e-1)" "unprognostic (3.61e-1)" "unprognostic (3.24e-1)" "unprognostic (1.18e-2)" "unprognostic (4.53e-2)" "unprognostic (1.42e-2)" "unprognostic (2.50e-1)" "unprognostic (5.05e-2)" "unprognostic (1.55e-3)" "unprognostic (1.37e-2)" "potential prognostic favorable (6.92e-4)" "unprognostic (1.28e-3)" "unprognostic (7.01e-2)" "potential prognostic unfavorable (7.99e-4)" "unprognostic (2.61e-2)" "unprognostic (7.43e-2)" "unprognostic (3.33e-2)" "unprognostic (3.14e-2)" "unprognostic (9.04e-2)" "unprognostic (1.47e-1)" "unprognostic (1.23e-1)" "unprognostic (2.42e-1)" "unprognostic (7.85e-2)" "unprognostic (3.99e-1)" "unprognostic (1.39e-1)" "unprognostic (1.17e-1)" "unprognostic (1.88e-1)" "unprognostic (6.59e-2)" "unprognostic (1.07e-1)" "unprognostic (9.89e-2)" "unprognostic (2.70e-1)" PSMG1 "c21-LRP, DSCR2, LRPC21, PAC1" ENSG00000183527 "Proteasome assembly chaperone 1" O95456 21 39174769-39183488 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 37.6" "Cell type enhanced" "Detected in many" "Early spermatids: 539.1;Late primary spermatocytes: 1403.1;Oocytes: 350.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057193, HPA070225" Approved Enhanced "Nucleoplasm,Golgi apparatus,Cytosol" No No 6900 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 57: Testis - Spermatogenesis" "Cluster 29: Forebrain - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 57 "Nucleoplasm, Golgi apparatus, Cytosol" "HPA057193: , HPA070225: " "unprognostic (1.91e-1)" "unprognostic (3.16e-2)" "unprognostic (4.93e-1)" "unprognostic (5.40e-2)" "unprognostic (1.41e-1)" "unprognostic (1.04e-1)" "unprognostic (3.26e-1)" "unprognostic (6.56e-2)" "unprognostic (1.37e-2)" "unprognostic (5.70e-3)" "unprognostic (1.49e-2)" "unprognostic (1.69e-1)" "unprognostic (2.53e-1)" "unprognostic (1.53e-3)" "unprognostic (1.71e-3)" "unprognostic (8.03e-2)" "unprognostic (2.63e-1)" "unprognostic (4.66e-2)" "unprognostic (1.52e-2)" "unprognostic (5.38e-2)" "unprognostic (3.92e-1)" "unprognostic (2.66e-1)" "unprognostic (1.45e-1)" "unprognostic (1.60e-3)" "unprognostic (1.82e-2)" "unprognostic (1.32e-2)" "unprognostic (8.74e-3)" "unprognostic (7.06e-2)" "unprognostic (2.20e-1)" "unprognostic (1.01e-1)" "unprognostic (1.70e-1)" PSMG2 "CLAST3, HCCA3, HsT1707, MDS003, MGC15092, PAC2, TNFSF5IP1" ENSG00000128789 "Proteasome assembly chaperone 2" Q969U7 18 12658043-12728945 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 529.3;Late primary spermatocytes: 796.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041517, HPA046741" Uncertain Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 39: Testis - Nuclear processes" "Cluster 9: Non-specific - Receptor signaling" "Cluster 13: Non-specific - Mixed function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 64 "Nuclear bodies" Nucleoplasm "HPA041517: , HPA046741: " "unprognostic (1.72e-1)" "unprognostic (7.49e-2)" "unprognostic (4.16e-1)" "unprognostic (1.70e-2)" "unprognostic (2.43e-1)" "unprognostic (3.92e-1)" "unprognostic (3.04e-1)" "potential prognostic favorable (9.75e-4)" "unprognostic (1.06e-1)" "unprognostic (1.89e-1)" "potential prognostic favorable (3.84e-4)" "unprognostic (5.96e-3)" "unprognostic (1.19e-1)" "unprognostic (3.12e-2)" "potential prognostic unfavorable (4.39e-5)" "unprognostic (1.75e-2)" "unprognostic (1.00e-1)" "unprognostic (5.71e-2)" "unprognostic (3.48e-1)" "unprognostic (3.01e-3)" "unprognostic (1.71e-1)" "potential prognostic unfavorable (2.49e-4)" "unprognostic (1.25e-1)" "unprognostic (2.79e-1)" "unprognostic (2.78e-1)" "unprognostic (1.60e-1)" "unprognostic (1.99e-2)" "unprognostic (4.93e-2)" "unprognostic (2.65e-1)" "unprognostic (1.29e-1)" "unprognostic (5.76e-3)" PSMG3 "C7orf48, MGC10911, PAC3" ENSG00000157778 "Proteasome assembly chaperone 3" Q9BT73 7 1567332-1571005 "Essential proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 138.7;Gastric progenitor cells: 116.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023876 Approved NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 67: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 62 "HPA023876: " "unprognostic (8.33e-2)" "unprognostic (8.27e-2)" "unprognostic (2.34e-1)" "unprognostic (1.35e-2)" "unprognostic (1.38e-2)" "unprognostic (1.08e-1)" "unprognostic (9.52e-2)" "unprognostic (3.64e-2)" "unprognostic (1.23e-1)" "unprognostic (9.01e-2)" "potential prognostic unfavorable (2.35e-5)" "unprognostic (1.79e-3)" "unprognostic (8.65e-3)" "validated prognostic unfavorable (5.89e-5)" "validated prognostic unfavorable (1.01e-4)" "potential prognostic unfavorable (6.38e-4)" "unprognostic (5.37e-2)" "unprognostic (1.07e-2)" "unprognostic (2.37e-1)" "unprognostic (7.60e-2)" "unprognostic (2.11e-1)" "unprognostic (7.88e-2)" "unprognostic (8.08e-3)" "unprognostic (1.55e-1)" "unprognostic (8.21e-2)" "unprognostic (1.96e-1)" "unprognostic (2.28e-1)" "unprognostic (2.38e-2)" "unprognostic (2.46e-1)" "unprognostic (1.22e-1)" "unprognostic (1.86e-1)" PSMG4 "C6orf86, PAC4" ENSG00000180822 "Proteasome assembly chaperone 4" Q5JS54 6 3231403-3303373 "Essential proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Oocytes: 529.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067652, HPA074376, HPA075846" Approved Approved Nucleoplasm,Mitochondria No No "Cluster 3: Non-specific - Nuclear processes" "Cluster 24: Non-specific - Transcription" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 30 "Nucleoplasm, Mitochondria" "HPA067652: , HPA074376: , HPA075846: " "unprognostic (1.76e-1)" "unprognostic (1.18e-1)" "unprognostic (1.49e-3)" "unprognostic (2.86e-1)" "unprognostic (7.64e-2)" "unprognostic (1.14e-1)" "unprognostic (1.34e-1)" "unprognostic (1.88e-3)" "unprognostic (1.77e-1)" "unprognostic (7.82e-3)" "unprognostic (1.94e-2)" "unprognostic (2.32e-1)" "unprognostic (5.71e-3)" "potential prognostic unfavorable (4.59e-4)" "unprognostic (5.49e-2)" "unprognostic (1.30e-1)" "unprognostic (1.21e-1)" "unprognostic (4.32e-2)" "unprognostic (7.90e-2)" "unprognostic (4.19e-2)" "unprognostic (9.78e-2)" "unprognostic (9.19e-3)" "unprognostic (2.22e-1)" "unprognostic (2.34e-1)" "unprognostic (5.81e-2)" "unprognostic (2.80e-2)" "unprognostic (2.87e-1)" "unprognostic (1.93e-1)" "unprognostic (3.96e-2)" "unprognostic (3.55e-1)" "unprognostic (1.93e-1)" PSORS1C1 "C6orf16, SEEK1" ENSG00000204540 "Psoriasis susceptibility 1 candidate 1" Q9UIG5 6 31114750-31140092 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 33 "testis: 105.5" "Cell type enriched" "Detected in some" 4 "Late spermatids: 419.2" "Cell type enhanced" "Detected in some" "fibroblast: 11.2;oligodendrocyte: 5.1" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Adrenocortical cancer: 1.2" "Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" HPA045049 Uncertain Nucleoplasm NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" Nucleoplasm "HPA045049: " "unprognostic (4.72e-2)" "unprognostic (6.76e-3)" "unprognostic (1.15e-1)" "unprognostic (1.34e-1)" "unprognostic (3.05e-1)" "unprognostic (6.58e-2)" "unprognostic (4.46e-2)" "unprognostic (2.77e-1)" "unprognostic (3.06e-3)" PSORS1C2 "C6orf17, SPR1" ENSG00000204538 "Psoriasis susceptibility 1 candidate 2" Q9UIG4 6 31137534-31139066 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 56 "skin 1: 250.4" "Cell type enhanced" "Detected in some" "Endometrial glandular cells: 1.0;Endometrial luminal cells: 2.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder Urothelial Carcinoma (TCGA): 24.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Macrophages, Skin - Hair cortex cells, Skin - Inner root sheath cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA061228 Enhanced "Secreted in other tissues" "No annotated function" NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 18 "HPA061228: " "unprognostic (2.99e-1)" "unprognostic (1.60e-1)" "unprognostic (1.36e-1)" "unprognostic (3.25e-1)" "unprognostic (3.75e-1)" "unprognostic (9.57e-2)" "unprognostic (2.46e-1)" PSPC1 "FLJ10955, PSP1" ENSG00000121390 "Paraspeckle component 1" Q8WXF1 13 19674752-19783019 "Predicted intracellular proteins, Transcription factors" "Biological rhythms, Immunity, Innate immunity, Transcription, Transcription regulation" "Activator, Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038904 Supported Enhanced "Nucleoplasm,Nucleoli fibrillar center" No No "Cluster 10: Non-specific - Membrane trafficking" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 34: Non-specific - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 328 Nucleoplasm "Nucleoli fibrillar center" "HPA038904: " "unprognostic (5.08e-2)" "unprognostic (1.70e-2)" "unprognostic (2.08e-1)" "unprognostic (2.64e-1)" "unprognostic (1.02e-1)" "unprognostic (2.69e-1)" "unprognostic (1.27e-1)" "potential prognostic favorable (7.32e-4)" "unprognostic (1.19e-1)" "unprognostic (5.61e-2)" "potential prognostic favorable (9.17e-4)" "unprognostic (1.66e-2)" "unprognostic (1.86e-1)" "unprognostic (3.36e-3)" "unprognostic (3.42e-3)" "potential prognostic unfavorable (2.62e-4)" "unprognostic (1.40e-3)" "unprognostic (2.11e-3)" "unprognostic (3.75e-2)" "unprognostic (4.86e-2)" "unprognostic (1.83e-1)" "unprognostic (5.68e-2)" "potential prognostic unfavorable (5.22e-4)" "unprognostic (3.71e-2)" "unprognostic (6.24e-2)" "unprognostic (1.55e-1)" "unprognostic (2.15e-1)" "unprognostic (2.93e-2)" "unprognostic (3.58e-1)" "unprognostic (4.92e-2)" "unprognostic (2.63e-1)" PSPH PSP ENSG00000146733 "Phosphoserine phosphatase" P78330 7 56011051-56051604 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Serine biosynthesis" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 137.6;Endometrial ciliated cells: 71.7;Late spermatids: 156.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Uterine Corpus Endometrial Carcinoma (TCGA): 318.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020376, HPA029515" Approved Approved Cytosol NA NA 4900 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 36: Brain & Liver - Signaling" "Cluster 25: Non-specific - Transcription" "Cluster 67: Non-specific - Unknown function" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 1 Cytosol "HPA020376: , HPA029515: " "unprognostic (6.89e-2)" "potential prognostic unfavorable (6.03e-4)" "unprognostic (1.06e-1)" "unprognostic (4.01e-2)" "unprognostic (4.28e-2)" "unprognostic (9.58e-2)" "unprognostic (7.35e-2)" "unprognostic (1.06e-2)" "unprognostic (3.18e-2)" "unprognostic (1.22e-2)" "potential prognostic favorable (3.01e-5)" "unprognostic (1.81e-1)" "unprognostic (7.49e-2)" "validated prognostic unfavorable (3.61e-4)" "validated prognostic unfavorable (1.65e-5)" "unprognostic (1.01e-3)" "unprognostic (1.54e-2)" "unprognostic (6.02e-3)" "unprognostic (2.88e-3)" "unprognostic (1.79e-1)" "unprognostic (3.41e-1)" "potential prognostic favorable (2.39e-5)" "unprognostic (3.56e-1)" "unprognostic (1.35e-1)" "unprognostic (6.69e-3)" "unprognostic (1.47e-2)" "unprognostic (3.92e-2)" "unprognostic (1.90e-1)" "unprognostic (4.53e-2)" "unprognostic (3.85e-2)" "unprognostic (1.21e-1)" PSPN PSP ENSG00000125650 Persephin O60542 19 6375148-6379058 "Predicted secreted proteins" "Growth factor" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 7 "Late spermatids: 55.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" CAB025366 Uncertain "Secreted in other tissues" "Growth factor" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 23: Non-specific - Transcription" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" "CAB025366: " "unprognostic (7.07e-2)" "unprognostic (5.44e-2)" "unprognostic (7.93e-2)" "unprognostic (2.51e-2)" "unprognostic (3.82e-1)" "unprognostic (1.40e-2)" "unprognostic (3.18e-1)" "unprognostic (1.95e-2)" "unprognostic (4.26e-2)" "unprognostic (3.86e-1)" "unprognostic (8.20e-2)" "unprognostic (1.60e-2)" "unprognostic (4.82e-2)" "unprognostic (3.33e-2)" "unprognostic (2.65e-1)" "unprognostic (1.82e-1)" "potential prognostic favorable (4.91e-4)" "unprognostic (4.65e-3)" "unprognostic (2.04e-2)" "unprognostic (7.04e-3)" "unprognostic (2.44e-1)" "unprognostic (6.62e-2)" "unprognostic (4.63e-2)" "unprognostic (2.56e-1)" "unprognostic (6.18e-2)" "unprognostic (2.28e-2)" PSRC1 DDA3 ENSG00000134222 "Proline and serine rich coiled-coil 1" Q6PGN9 1 109279556-109283186 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 91.4;retina: 38.7" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 21.3;Bergmann glia: 29.6;Cytotrophoblasts: 19.8;Extravillous trophoblasts: 31.2;Megakaryocytes: 24.7;Microglia: 22.2;Migrating cytotrophoblasts: 30.1;Oligodendrocytes: 72.2;Peritubular myoid cells: 43.6;Retinal pigment epithelial cells: 29.8;Rod photoreceptor cells: 39.9" "Cell type enhanced" "Detected in many" "oligodendrocyte: 97.2" "Cancer enriched" "Detected in all" 4 "Glioblastoma Multiforme (TCGA): 136.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 12.1" "Group enriched" "Detected in many" 11 "dendritic cells: 5.4;granulocytes: 7.2;monocytes: 12.1" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Prostate - Fibroblasts, Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach)" "Group enriched" "Detected in many" 5 "amygdala: 3.5;cerebral cortex: 7.7;hippocampal formation: 5.7;white matter: 3.4" "Low region specificity" "Detected in all" HPA056561 Supported Nucleoplasm,Cytosol NA Yes "Cluster 7: Non-specific - Innate immune response" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 37: Non-specific - mRNA processing" "Cluster 27: Non-specific - Cell proliferation" 8 Cytosol Nucleoplasm "HPA056561: " "unprognostic (2.81e-1)" "unprognostic (4.53e-1)" "unprognostic (1.76e-1)" "unprognostic (1.23e-1)" "unprognostic (3.46e-2)" "unprognostic (2.04e-1)" "unprognostic (2.46e-1)" "unprognostic (8.99e-3)" "unprognostic (5.57e-2)" "unprognostic (2.67e-3)" "potential prognostic unfavorable (2.42e-8)" "unprognostic (7.55e-3)" "unprognostic (1.43e-2)" "validated prognostic unfavorable (2.57e-11)" "validated prognostic unfavorable (2.43e-4)" "potential prognostic unfavorable (6.37e-4)" "unprognostic (1.61e-3)" "potential prognostic favorable (3.85e-4)" "unprognostic (1.83e-2)" "unprognostic (5.84e-2)" "unprognostic (5.31e-2)" "unprognostic (1.03e-2)" "unprognostic (8.92e-2)" "unprognostic (1.85e-1)" "unprognostic (6.02e-2)" "unprognostic (2.28e-1)" "unprognostic (6.41e-2)" "unprognostic (8.74e-2)" "unprognostic (3.54e-1)" "unprognostic (1.46e-1)" "unprognostic (1.06e-1)" PSTK "C10orf89, MGC35392" ENSG00000179988 "Phosphoseryl-tRNA kinase" Q8IV42 10 122954381-122997513 "Enzymes, Predicted intracellular proteins" "Protein biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 87.6;Oocytes: 124.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037780, HPA037781" Approved Approved "Nucleoli,Nuclear bodies,Actin filaments" No No "Cluster 3: Non-specific - Nuclear processes" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 7: Non-specific - Transcription" 1 "Actin filaments" "Nucleoli, Nuclear bodies" "HPA037780: , HPA037781: " "unprognostic (1.39e-2)" "unprognostic (1.17e-1)" "unprognostic (8.10e-2)" "unprognostic (1.18e-3)" "unprognostic (7.07e-2)" "unprognostic (1.39e-1)" "unprognostic (1.17e-1)" "unprognostic (8.67e-3)" "unprognostic (8.48e-2)" "unprognostic (4.90e-2)" "unprognostic (4.07e-2)" "unprognostic (3.06e-1)" "unprognostic (2.98e-1)" "unprognostic (1.13e-1)" "unprognostic (4.25e-3)" "unprognostic (1.80e-1)" "unprognostic (3.84e-2)" "unprognostic (6.41e-2)" "unprognostic (3.26e-1)" "unprognostic (2.61e-1)" "potential prognostic unfavorable (7.12e-4)" "unprognostic (2.03e-2)" "unprognostic (2.47e-2)" "unprognostic (1.59e-2)" "unprognostic (6.23e-3)" "unprognostic (6.86e-2)" "unprognostic (1.70e-1)" "unprognostic (1.54e-1)" "unprognostic (1.50e-3)" "unprognostic (1.46e-2)" PSTPIP1 "CD2BP1, CD2BP1L, CD2BP1S, H-PIP, PAPAS, PSTPIP" ENSG00000140368 "Proline-serine-threonine phosphatase interacting protein 1" O43586 15 76993359-77037475 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell adhesion, Endocytosis, Immunity, Inflammatory response, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 55.1;lymphoid tissue: 30.4" "Cell type enhanced" "Detected in many" "cDC: 51.5;Hofbauer cells: 65.6;Monocyte progenitors: 70.1;monocytes: 77.1;Neutrophil progenitors: 128.8;Neutrophils: 130.1;NK-cells: 59.0;Oocytes: 520.4;T-cells: 62.2" "Cell type enriched" "Detected in many" 9 "leukocyte: 79.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Leukemia: 14.9;lymphoma: 11.2" "Adipose subcutaneous - Macrophages, Adrenal gland - Macrophages, Heart muscle - Macrophages, Kidney - T-cells, Liver - T-cells, Prostate - T-cells, Skeletal muscle - Macrophages, Thyroid gland - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA010116, HPA010600, HPA072744" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 53 "Plasma membrane, Cytosol" "HPA010116: , HPA010600: , HPA072744: " "unprognostic (3.19e-2)" "unprognostic (2.10e-2)" "unprognostic (5.36e-3)" "potential prognostic favorable (3.83e-5)" "unprognostic (3.52e-1)" "unprognostic (1.98e-1)" "unprognostic (9.02e-3)" "unprognostic (2.18e-2)" "unprognostic (2.75e-2)" "unprognostic (9.75e-3)" "unprognostic (7.24e-2)" "unprognostic (2.68e-1)" "unprognostic (1.16e-1)" "unprognostic (2.96e-3)" "potential prognostic favorable (3.16e-4)" "unprognostic (7.50e-2)" "unprognostic (1.16e-1)" "unprognostic (1.03e-1)" "unprognostic (7.22e-2)" "unprognostic (1.95e-2)" "unprognostic (6.76e-2)" "unprognostic (3.18e-1)" "unprognostic (3.51e-2)" "unprognostic (5.74e-2)" "unprognostic (7.83e-2)" "unprognostic (4.78e-2)" "unprognostic (1.30e-1)" "unprognostic (1.90e-1)" "unprognostic (2.67e-1)" "unprognostic (4.30e-1)" PSTPIP2 ENSG00000152229 "Proline-serine-threonine phosphatase interacting protein 2" Q9H939 18 45983536-46072272 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "bone marrow: 68.4;lymphoid tissue: 60.8;skeletal muscle: 30.9" "Cell type enhanced" "Detected in many" "Megakaryocyte progenitors: 300.5;Megakaryocyte-Erythroid progenitors: 242.4;Megakaryocytes: 408.0;monocytes: 236.6;Neutrophil progenitors: 676.4;Neutrophils: 1122.8;Platelets: 411.0;Tuft cells: 1095.2" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 41.1;leukocyte: 94.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 112.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040944 Enhanced Approved "Plasma membrane,Cytosol" NA No 1200000 "Cluster 25: Non-specific - Unknown function" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 5 "Plasma membrane" Cytosol "HPA040944: " "unprognostic (4.13e-1)" "unprognostic (2.53e-1)" "unprognostic (2.08e-1)" "unprognostic (2.03e-3)" "unprognostic (4.47e-1)" "unprognostic (1.82e-1)" "unprognostic (3.50e-2)" "unprognostic (1.35e-1)" "unprognostic (1.27e-1)" "unprognostic (1.13e-3)" "unprognostic (1.34e-2)" "unprognostic (8.45e-2)" "potential prognostic unfavorable (4.75e-4)" "unprognostic (3.02e-2)" "unprognostic (1.12e-1)" "potential prognostic favorable (6.09e-4)" "unprognostic (1.67e-1)" "unprognostic (9.59e-2)" "unprognostic (2.40e-2)" "unprognostic (2.65e-1)" "unprognostic (8.62e-3)" "unprognostic (8.33e-2)" "unprognostic (1.45e-3)" "unprognostic (2.06e-1)" "unprognostic (1.28e-1)" "unprognostic (1.32e-1)" "unprognostic (2.37e-1)" "unprognostic (8.88e-2)" "unprognostic (5.13e-2)" "unprognostic (1.46e-1)" "unprognostic (1.73e-1)" PTAFR ENSG00000169403 "Platelet activating factor receptor" P25105 1 28147166-28193936 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 38.8;lymphoid tissue: 29.0" "Cell type enhanced" "Detected in many" "cDC: 80.2;Hofbauer cells: 113.5;Kupffer cells: 146.6;Macrophages: 83.7;Mast cells: 71.9;Microglia: 114.8;Monocyte progenitors: 64.9;monocytes: 144.8;Neutrophil progenitors: 117.1;Neutrophils: 466.0;Platelets: 94.8" "Cell type enriched" "Detected in many" 10 "central nervous system macrophage: 142.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 256.9;eosinophil: 908.6;neutrophil: 749.9" "Group enriched" "Detected in many" 5 "granulocytes: 908.6;monocytes: 256.9" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 22.4" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Lung - Macrophages, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Pituitary gland - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA027543 Approved Supported "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 26 "Plasma membrane" "Nucleoplasm, Vesicles" "HPA027543: " "unprognostic (1.18e-1)" "unprognostic (1.95e-2)" "unprognostic (3.10e-1)" "unprognostic (1.54e-1)" "unprognostic (2.33e-1)" "unprognostic (3.20e-1)" "unprognostic (1.88e-1)" "unprognostic (1.41e-1)" "unprognostic (2.33e-2)" "unprognostic (6.16e-2)" "unprognostic (6.90e-2)" "unprognostic (2.18e-1)" "unprognostic (1.48e-2)" "unprognostic (2.50e-2)" "unprognostic (2.64e-1)" "unprognostic (1.13e-1)" "unprognostic (1.33e-2)" "unprognostic (1.11e-1)" "unprognostic (3.80e-2)" "unprognostic (4.87e-2)" "unprognostic (1.22e-2)" "unprognostic (1.21e-1)" "unprognostic (3.87e-3)" "unprognostic (4.20e-1)" "unprognostic (1.59e-1)" "unprognostic (1.16e-1)" "unprognostic (7.46e-2)" "unprognostic (1.64e-1)" "unprognostic (2.70e-2)" "unprognostic (1.45e-1)" "unprognostic (3.59e-1)" PTAR1 ENSG00000188647 "Protein prenyltransferase alpha subunit repeat containing 1" Q7Z6K3 9 69709522-69760011 "Predicted intracellular proteins" "Prenyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021248, HPA022781" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 61: Non-specific - Transcription" "Cluster 39: Astrocytes - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 7 "Plasma membrane, Cytosol" "HPA021248: , HPA022781: " "unprognostic (5.82e-3)" "unprognostic (1.68e-1)" "unprognostic (3.10e-2)" "unprognostic (7.43e-2)" "unprognostic (7.20e-2)" "unprognostic (5.18e-3)" "unprognostic (1.73e-1)" "unprognostic (4.61e-1)" "unprognostic (1.74e-2)" "unprognostic (5.48e-2)" "validated prognostic favorable (2.66e-7)" "validated prognostic favorable (5.24e-4)" "unprognostic (2.81e-2)" "unprognostic (1.53e-1)" "unprognostic (6.01e-2)" "unprognostic (2.47e-1)" "unprognostic (1.51e-1)" "unprognostic (2.16e-1)" "unprognostic (7.08e-2)" "unprognostic (1.28e-1)" "unprognostic (3.53e-1)" "unprognostic (2.75e-1)" "unprognostic (3.92e-2)" "unprognostic (1.60e-1)" "unprognostic (4.18e-2)" "unprognostic (1.46e-2)" "unprognostic (2.04e-1)" "unprognostic (2.15e-1)" "unprognostic (3.52e-1)" "unprognostic (1.36e-1)" "unprognostic (1.98e-1)" PTBP1 "HNRNP-I, HNRPI, pPTB, PTB, PTB-1, PTB2, PTB3, PTB4" ENSG00000011304 "Polypyrimidine tract binding protein 1" P26599 19 797075-812327 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Activator, Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB013507 Supported Supported Nucleoplasm NA NA 1900000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 60: Stomach - Digestion" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 23: Non-specific - Transcription" "Cluster 20: Non-specific - Transcription regulation" 69 Nucleoplasm "CAB013507: " "unprognostic (2.03e-1)" "unprognostic (1.37e-1)" "unprognostic (2.14e-1)" "unprognostic (4.58e-3)" "unprognostic (1.24e-1)" "unprognostic (8.68e-2)" "unprognostic (1.96e-1)" "unprognostic (3.78e-1)" "unprognostic (2.40e-1)" "unprognostic (4.90e-3)" "validated prognostic favorable (6.27e-4)" "validated prognostic favorable (2.34e-4)" "unprognostic (2.49e-1)" "potential prognostic unfavorable (1.88e-5)" "unprognostic (3.66e-3)" "potential prognostic unfavorable (8.01e-4)" "unprognostic (1.22e-3)" "unprognostic (9.67e-2)" "unprognostic (1.11e-2)" "unprognostic (1.15e-1)" "unprognostic (1.85e-2)" "unprognostic (1.82e-2)" "unprognostic (4.00e-2)" "unprognostic (3.03e-3)" "unprognostic (4.36e-2)" "unprognostic (1.97e-1)" "unprognostic (3.99e-2)" "unprognostic (6.39e-2)" "unprognostic (1.95e-1)" "unprognostic (1.21e-1)" "unprognostic (6.55e-3)" PTBP2 "brPTB, nPTB, PTB, PTBLP" ENSG00000117569 "Polypyrimidine tract binding protein 2" Q9UKA9 1 96721665-96823738 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 754.6;Oligodendrocytes: 749.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047420 Uncertain Approved Nucleoplasm NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 11 Nucleoplasm "HPA047420: " "unprognostic (1.44e-1)" "unprognostic (1.17e-1)" "unprognostic (7.00e-2)" "unprognostic (6.26e-2)" "unprognostic (1.98e-1)" "unprognostic (1.94e-1)" "unprognostic (1.97e-2)" "potential prognostic favorable (3.54e-4)" "unprognostic (2.33e-2)" "unprognostic (7.27e-3)" "unprognostic (1.91e-1)" "unprognostic (3.17e-3)" "potential prognostic favorable (4.11e-4)" "potential prognostic unfavorable (7.07e-5)" "unprognostic (8.27e-2)" "unprognostic (1.73e-1)" "unprognostic (6.57e-2)" "unprognostic (5.30e-2)" "unprognostic (1.79e-1)" "unprognostic (1.73e-2)" "unprognostic (3.59e-2)" "unprognostic (3.03e-3)" "unprognostic (8.76e-2)" "unprognostic (5.22e-2)" "unprognostic (1.59e-1)" "unprognostic (1.13e-1)" "unprognostic (4.57e-2)" "unprognostic (3.88e-2)" "unprognostic (2.02e-1)" "unprognostic (3.32e-2)" "potential prognostic unfavorable (6.87e-4)" PTBP3 "DKFZp781I1117, ROD1" ENSG00000119314 "Polypyrimidine tract binding protein 3" O95758 9 112217716-112333664 "Predicted intracellular proteins" "Differentiation, Erythrocyte maturation, mRNA processing, mRNA splicing" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 647.2;Neutrophils: 996.2;Renal collecting duct principal cells: 750.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048374 Approved Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 33: Neurons - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 10 Nucleoplasm "HPA048374: " "unprognostic (2.05e-1)" "unprognostic (1.10e-1)" "unprognostic (2.04e-2)" "unprognostic (4.06e-2)" "unprognostic (8.42e-2)" "unprognostic (3.30e-1)" "unprognostic (2.18e-2)" "unprognostic (3.22e-1)" "unprognostic (1.96e-2)" "potential prognostic favorable (1.85e-6)" "unprognostic (1.70e-2)" "unprognostic (2.72e-2)" "unprognostic (2.12e-3)" "unprognostic (3.79e-3)" "unprognostic (1.41e-2)" "unprognostic (1.92e-3)" "unprognostic (1.01e-1)" "unprognostic (3.07e-2)" "unprognostic (3.70e-2)" "potential prognostic unfavorable (3.54e-4)" "unprognostic (1.57e-1)" "unprognostic (1.45e-2)" "potential prognostic favorable (1.34e-5)" "unprognostic (2.02e-2)" "unprognostic (8.27e-2)" "unprognostic (5.44e-2)" "unprognostic (1.25e-1)" "unprognostic (2.54e-3)" "unprognostic (2.29e-1)" PTCD1 KIAA0632 ENSG00000106246 "Pentatricopeptide repeat domain 1" O75127 7 99416739-99466163 "Predicted intracellular proteins" "tRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Epicardial cells: 25.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020106, HPA047679" Uncertain Approved Mitochondria NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 24: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 39: Non-specific - Transcription" "Cluster 22: Non-specific - Basic cellular functions" 46 Mitochondria "HPA020106: , HPA047679: " "unprognostic (1.29e-1)" "unprognostic (3.87e-1)" "unprognostic (4.43e-2)" "unprognostic (4.47e-2)" "unprognostic (2.17e-2)" "unprognostic (1.84e-1)" "unprognostic (1.62e-1)" "unprognostic (4.43e-2)" "unprognostic (5.18e-3)" "potential prognostic unfavorable (2.79e-4)" "unprognostic (4.31e-3)" "unprognostic (1.44e-2)" "unprognostic (5.48e-2)" "validated prognostic unfavorable (7.28e-5)" "validated prognostic unfavorable (1.73e-4)" "unprognostic (5.79e-2)" "unprognostic (5.34e-2)" "unprognostic (2.39e-2)" "unprognostic (6.60e-3)" "unprognostic (1.03e-1)" "unprognostic (1.19e-1)" "unprognostic (1.15e-2)" "unprognostic (1.55e-1)" "unprognostic (4.44e-3)" "unprognostic (4.49e-1)" "unprognostic (1.52e-1)" "unprognostic (6.43e-2)" "unprognostic (1.95e-1)" "unprognostic (4.90e-1)" "unprognostic (1.68e-2)" "unprognostic (3.34e-2)" PTCD2 FLJ12598 ENSG00000049883 "Pentatricopeptide repeat domain 2" Q8WV60 5 72320367-72368395 "Predicted intracellular proteins" "mRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 62.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043686 Approved NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 6 "HPA043686: " "unprognostic (3.19e-1)" "unprognostic (1.47e-2)" "unprognostic (6.93e-2)" "unprognostic (5.84e-2)" "unprognostic (2.51e-1)" "unprognostic (6.58e-2)" "unprognostic (2.99e-1)" "unprognostic (2.94e-2)" "unprognostic (1.04e-1)" "unprognostic (2.50e-1)" "potential prognostic favorable (4.94e-7)" "unprognostic (3.54e-1)" "potential prognostic favorable (2.30e-4)" "unprognostic (5.04e-1)" "unprognostic (4.08e-1)" "unprognostic (5.88e-3)" "unprognostic (1.31e-2)" "unprognostic (8.52e-2)" "unprognostic (3.96e-2)" "unprognostic (1.79e-3)" "unprognostic (3.33e-2)" "unprognostic (5.72e-2)" "unprognostic (2.57e-3)" "unprognostic (1.93e-1)" "unprognostic (1.33e-1)" "unprognostic (8.13e-2)" "unprognostic (2.81e-1)" "unprognostic (3.64e-3)" "unprognostic (3.07e-1)" "unprognostic (3.75e-2)" "unprognostic (1.04e-1)" PTCD3 "DKFZp666K071, FLJ20758" ENSG00000132300 "Pentatricopeptide repeat domain 3" Q96EY7 2 86106223-86142157 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Translation regulation" "Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041154, HPA041382" Supported Supported Mitochondria NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 52: Non-specific - Cellular respiration" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 17: Non-specific - RNA processing" 93 Mitochondria "HPA041154: , HPA041382: " "unprognostic (6.94e-2)" "unprognostic (1.02e-2)" "unprognostic (1.36e-1)" "unprognostic (3.15e-2)" "unprognostic (3.39e-1)" "unprognostic (3.34e-2)" "unprognostic (3.30e-2)" "potential prognostic favorable (6.40e-4)" "unprognostic (1.37e-1)" "unprognostic (6.83e-2)" "unprognostic (8.30e-2)" "unprognostic (1.35e-2)" "unprognostic (3.61e-3)" "unprognostic (5.25e-3)" "unprognostic (8.53e-3)" "unprognostic (3.54e-1)" "unprognostic (8.50e-2)" "unprognostic (3.58e-3)" "unprognostic (9.14e-3)" "unprognostic (1.23e-3)" "unprognostic (1.03e-1)" "unprognostic (2.36e-3)" "unprognostic (2.91e-3)" "unprognostic (1.37e-3)" "potential prognostic favorable (1.69e-4)" "unprognostic (2.29e-1)" "unprognostic (1.14e-1)" "unprognostic (4.57e-2)" "unprognostic (3.99e-1)" "potential prognostic unfavorable (1.02e-4)" "unprognostic (1.05e-2)" PTCH1 "BCNS, NBCCS, PTCH" ENSG00000185920 "Patched 1" Q13635 9 95442980-95517057 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Cancer-related genes, Disease variant, Holoprosencephaly, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 34.5" "Cell type enhanced" "Detected in many" "Bergmann glia: 406.1;Endometrial stromal cells: 132.7;Late spermatids: 423.0;Leydig cells: 386.2;Peritubular myoid cells: 686.1" "Cell type enhanced" "Detected in all" "Bergmann glia: 439.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 6.2" "Lineage enriched" "Detected in single" 9 "T-cells: 6.2" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Testis - Peritubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013717, HPA075072" Uncertain Approved "Golgi apparatus,Primary cilium" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 13: Lung - Secretion" "Cluster 46: Brainstem - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 94: Gonadal somatic cells - Mixed function" 16 "Golgi apparatus" "Primary cilium" "CAB013717: , HPA075072: " "unprognostic (7.06e-2)" "unprognostic (1.01e-1)" "unprognostic (4.69e-2)" "unprognostic (1.03e-1)" "unprognostic (1.90e-1)" "unprognostic (2.33e-2)" "unprognostic (7.23e-2)" "unprognostic (1.34e-1)" "unprognostic (1.54e-1)" "unprognostic (3.23e-1)" "potential prognostic favorable (4.44e-7)" "unprognostic (2.91e-3)" "unprognostic (2.84e-1)" "unprognostic (2.17e-2)" "unprognostic (1.91e-2)" "unprognostic (1.17e-1)" "unprognostic (1.96e-1)" "potential prognostic favorable (8.18e-5)" "unprognostic (1.25e-2)" "unprognostic (1.94e-1)" "unprognostic (3.85e-2)" "unprognostic (6.44e-2)" "unprognostic (9.19e-2)" "unprognostic (7.93e-3)" "unprognostic (1.41e-1)" "unprognostic (1.05e-1)" "unprognostic (9.31e-2)" "unprognostic (5.07e-2)" "unprognostic (8.53e-2)" "unprognostic (4.11e-3)" PTCH2 ENSG00000117425 "Patched 2" Q9Y6C5 1 44819844-44843253 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 55.6;salivary gland: 70.9" "Group enriched" "Detected in many" 5 "Leydig cells: 1885.2;Peritubular myoid cells: 756.4" "Cell type enhanced" "Detected in all" "Bergmann glia: 220.2" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 16.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Minor Salivary Gland - Minor salivary glandular cells, Stomach - Fibroblasts, Testis - Peritubular cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA046839 Supported "Nucleoli,Plasma membrane" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 94: Gonadal somatic cells - Mixed function" "Plasma membrane" Nucleoli "HPA046839: " "unprognostic (4.14e-3)" "potential prognostic favorable (3.51e-4)" "unprognostic (9.51e-2)" "unprognostic (9.40e-3)" "unprognostic (1.35e-1)" "unprognostic (2.95e-1)" "unprognostic (8.80e-2)" "potential prognostic unfavorable (8.83e-4)" "unprognostic (9.92e-2)" "unprognostic (5.10e-3)" "potential prognostic favorable (5.89e-4)" "unprognostic (2.81e-1)" "unprognostic (1.62e-2)" "unprognostic (7.37e-2)" "potential prognostic favorable (3.67e-5)" "unprognostic (5.16e-2)" "unprognostic (2.48e-1)" "unprognostic (8.01e-3)" "unprognostic (1.12e-2)" "unprognostic (1.59e-1)" "unprognostic (3.98e-2)" "unprognostic (2.38e-1)" PTCHD1 FLJ30296 ENSG00000165186 "Patched domain containing 1" Q96NR3 X 23334849-23404374 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Autism, Autism spectrum disorder, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.1;intestine: 6.1" "Cell type enhanced" "Detected in many" "Astrocytes: 105.5;Brain excitatory neurons: 64.4;Brain inhibitory neurons: 33.5;Breast secretory cells: 48.6;Corticotrophs: 39.2;Epididymal principal cells: 47.6;Gonadotrophs: 78.2;Leydig cells: 29.3;Other brain neurons: 30.5;Pituitary stem cells: 41.7;Retinal amacrine cells: 45.6;Transitional alveolar cells: 36.9;Tuft cells: 149.9" "Cell type enhanced" "Detected in all" "astrocyte: 142.9;upper rhombic lip: 156.6" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 1.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 2.0;Rhabdoid: 1.4" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Heart muscle - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA046110 Uncertain NA NA "Cluster 64: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 2: Cerebellar granular cells - Neuronal signaling" "HPA046110: " "unprognostic (1.02e-1)" "unprognostic (2.30e-1)" "unprognostic (2.04e-2)" "unprognostic (1.64e-1)" "potential prognostic favorable (1.53e-4)" "unprognostic (1.06e-1)" PTCHD3 "FLJ44037, PTR" ENSG00000182077 "Patched domain containing 3 (gene/pseudogene)" 10 27397121-27414368 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 5 "testis: 3.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA044613 Approved NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 98: Neurons - Neurotransmission & signaling" "HPA044613: " PTCHD4 "C6orf138, dJ402H5.2, FLJ41841, PTCH53" ENSG00000244694 "Patched domain containing 4" Q6ZW05 6 47856673-48111197 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 67.4;Brain inhibitory neurons: 268.6;Microglia: 76.9;Other brain neurons: 79.2;Pituitary stem cells: 84.1;Retinal amacrine cells: 145.7;Retinal ganglion cells: 355.4" "Cell type enhanced" "Detected in many" "LAMP5-LHX6 and Chandelier: 1007.7;MGE interneuron: 608.5" "Group enriched" "Detected in some" 5 "Kidney Chromophobe (TCGA): 3.3;Kidney Renal Clear Cell Carcinoma (TCGA): 1.5;Kidney Renal Papillary Cell Carcinoma (TCGA): 4.0;Skin Cutaneous Melanoma (TCGA): 1.6;Thyroid Carcinoma (TCGA): 6.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "testis cancer: 18.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA041276 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 53: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 109: Neurons - Neuronal signaling" "Plasma membrane, Cytosol" "HPA041276: " "unprognostic (8.57e-3)" "potential prognostic unfavorable (2.68e-5)" "unprognostic (2.49e-3)" "unprognostic (6.84e-3)" "potential prognostic favorable (1.21e-4)" "potential prognostic favorable (5.75e-7)" "unprognostic (4.91e-2)" "unprognostic (3.25e-1)" "unprognostic (7.83e-2)" "unprognostic (4.99e-3)" PTCRA "PT-ALPHA, PTA" ENSG00000171611 "Pre T cell antigen receptor alpha" Q6ISU1 6 42915989-42925838 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 46 "lymphoid tissue: 119.8" "Cell type enriched" "Detected in some" 17 "Platelets: 3217.0" "Cell type enhanced" "Detected in single" "central nervous system macrophage: 2.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 46 "plasmacytoid DC: 411.7" "Lineage enriched" "Detected in many" 46 "dendritic cells: 411.7" "Group enriched" "Detected in some" 14 "Leukemia: 9.2;skin cancer: 4.0" "Spleen - Macrophages" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 80: Thymus - Adaptive immune response" "Cluster 6: Non-specific - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 47: Platelets - Hemostasis" "unprognostic (7.82e-2)" "unprognostic (8.84e-3)" "unprognostic (1.07e-1)" "unprognostic (1.38e-3)" "unprognostic (5.85e-2)" PTDSS1 "KIAA0024, PSS1, PSSA" ENSG00000156471 "Phosphatidylserine synthase 1" P48651 8 96261902-96336995 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Transferase "Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 180.1;Syncytiotrophoblasts: 125.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 10.4" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016852 Uncertain Approved "Nucleoplasm,Endoplasmic reticulum" NA NA "Cluster 18: Non-specific - Translation" "Cluster 35: Non-specific - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 40: Non-specific - Unknown function" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 5 "Endoplasmic reticulum" Nucleoplasm "HPA016852: " "unprognostic (6.91e-2)" "unprognostic (1.84e-1)" "unprognostic (1.04e-1)" "unprognostic (2.91e-2)" "unprognostic (1.07e-1)" "unprognostic (7.03e-2)" "unprognostic (5.02e-2)" "unprognostic (8.11e-3)" "unprognostic (5.34e-2)" "potential prognostic unfavorable (1.46e-5)" "unprognostic (1.14e-3)" "unprognostic (2.50e-1)" "unprognostic (3.17e-1)" "unprognostic (2.28e-3)" "unprognostic (8.25e-3)" "unprognostic (1.83e-2)" "unprognostic (8.33e-3)" "unprognostic (2.85e-2)" "unprognostic (5.53e-1)" "unprognostic (3.74e-1)" "unprognostic (2.01e-1)" "unprognostic (4.31e-3)" "unprognostic (5.77e-2)" "unprognostic (2.60e-2)" "unprognostic (2.13e-3)" "unprognostic (2.33e-1)" "unprognostic (2.25e-1)" "unprognostic (5.91e-3)" "unprognostic (1.80e-1)" PTDSS2 PSS2 ENSG00000174915 "Phosphatidylserine synthase 2" Q9BVG9 11 448268-491399 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 58.1;Late primary spermatocytes: 79.6;Late spermatids: 255.3;Oligodendrocytes: 39.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038928, HPA038929" Approved NA NA "Cluster 67: Testis - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 40: Non-specific - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 53 "HPA038928: , HPA038929: " "unprognostic (2.07e-2)" "unprognostic (4.17e-2)" "unprognostic (3.84e-3)" "unprognostic (6.57e-3)" "unprognostic (1.61e-1)" "unprognostic (6.79e-2)" "unprognostic (1.69e-1)" "unprognostic (8.87e-3)" "unprognostic (1.99e-1)" "unprognostic (8.36e-2)" "unprognostic (3.49e-3)" "unprognostic (8.91e-3)" "unprognostic (2.92e-2)" "validated prognostic unfavorable (2.24e-5)" "validated prognostic unfavorable (5.95e-4)" "unprognostic (1.98e-1)" "unprognostic (2.26e-1)" "unprognostic (5.02e-3)" "unprognostic (5.86e-2)" "unprognostic (6.29e-2)" "unprognostic (1.82e-1)" "unprognostic (6.64e-2)" "potential prognostic unfavorable (1.28e-4)" "unprognostic (2.55e-1)" "unprognostic (2.79e-3)" "potential prognostic favorable (1.83e-5)" "unprognostic (5.38e-2)" "unprognostic (1.06e-2)" "unprognostic (2.59e-1)" "unprognostic (1.16e-1)" "unprognostic (5.14e-2)" PTEN "BZS, MHAM, MMAC1, PTEN1, TEP1" ENSG00000171862 "Phosphatase and tensin homolog" P60484 10 87862563-87971930 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Lipid metabolism, Neurogenesis" "Hydrolase, Protein phosphatase" "Autism spectrum disorder, Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 120.7;Bergmann glia: 129.2;Brain excitatory neurons: 240.2;Brain inhibitory neurons: 173.6;Choroid plexus epithelial cells: 282.1;Distal convoluted tubule cells: 220.3;Ependymal cells: 183.9;Loop of henle epithelial cells: 171.9;Microglia: 280.4;Oligodendrocyte progenitor cells: 154.6;Other brain neurons: 162.6;Papillary tip epithelial cells: 211.0;Pericytes: 139.3;Podocytes: 155.6;Proximal tubule cells: 150.2;Renal collecting duct intercalated cells: 148.0;Renal collecting duct principal cells: 211.2;Renal connecting tubule cells: 180.9" "Cell type enhanced" "Detected in all" "pericyte: 1886.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 63.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Breast - Adipocytes (Breast), Prostate - Fibroblasts, Spleen - Fibroblasts_2, Testis - Early spermatids" "CAB004076, HPA031335, CAB080153, CAB080155, CAB080157" Approved Supported "Nucleoplasm,Cytosol,Mid piece,Principal piece" "Intracellular and membrane" Enzyme NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 61: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 22: Non-specific - Basic cellular functions" 159 "Nucleoplasm, Cytosol" "Mid piece, Principal piece" "CAB004076: , CAB080153: , CAB080155: , CAB080157: , HPA031335: " "unprognostic (3.43e-2)" "unprognostic (1.10e-1)" "unprognostic (2.81e-1)" "unprognostic (2.87e-2)" "unprognostic (9.21e-2)" "unprognostic (8.12e-3)" "unprognostic (7.66e-2)" "unprognostic (1.53e-3)" "unprognostic (1.45e-2)" "unprognostic (6.48e-2)" "unprognostic (2.23e-3)" "unprognostic (4.92e-2)" "unprognostic (1.28e-2)" "unprognostic (4.94e-2)" "unprognostic (2.00e-1)" "unprognostic (8.99e-2)" "unprognostic (1.60e-1)" "unprognostic (1.45e-1)" "unprognostic (7.26e-2)" "unprognostic (3.76e-1)" "unprognostic (7.93e-3)" "unprognostic (5.20e-2)" "unprognostic (7.11e-2)" "unprognostic (1.17e-1)" "unprognostic (1.97e-1)" "unprognostic (4.28e-2)" "unprognostic (2.16e-1)" "unprognostic (1.19e-1)" "unprognostic (7.27e-2)" "unprognostic (1.11e-2)" "unprognostic (1.55e-2)" PTER ENSG00000165983 "Phosphotriesterase related" Q96BW5 10 16436943-16513745 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 40.6" "Cell type enhanced" "Detected in many" "Pancreatic acinar cells: 125.5;Proximal tubule cells: 145.1;Urothelial cells: 136.4" "Group enriched" "Detected in many" 4 "central nervous system macrophage: 29.9;choroid plexus epithelial cell: 47.3;fibroblast: 19.8;leukocyte: 46.8;pericyte: 20.5;vascular associated smooth muscle cell: 14.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038044, HPA038045" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 36: Brain & Liver - Signaling" "Cluster 51: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 69: Urothelial cells - Basic cellular functions" 1 Nucleoplasm Cytosol "HPA038044: , HPA038045: " "unprognostic (2.19e-1)" "unprognostic (2.28e-2)" "unprognostic (3.20e-1)" "unprognostic (3.70e-1)" "unprognostic (8.75e-3)" "unprognostic (6.27e-2)" "unprognostic (3.59e-2)" "unprognostic (3.21e-1)" "unprognostic (2.01e-1)" "unprognostic (5.76e-3)" "potential prognostic favorable (5.49e-9)" "unprognostic (3.11e-1)" "unprognostic (4.03e-3)" "unprognostic (1.03e-3)" "unprognostic (1.57e-2)" "potential prognostic unfavorable (1.25e-4)" "unprognostic (2.58e-1)" "unprognostic (8.54e-2)" "unprognostic (7.13e-2)" "unprognostic (1.18e-1)" "unprognostic (1.53e-1)" "potential prognostic unfavorable (7.14e-4)" "unprognostic (4.70e-1)" "unprognostic (6.47e-2)" "unprognostic (1.46e-1)" "unprognostic (8.76e-2)" "unprognostic (1.42e-1)" "unprognostic (2.93e-1)" "unprognostic (7.95e-2)" "unprognostic (1.05e-1)" "unprognostic (3.86e-2)" PTF1A "bHLHa29, p48, PTF1-p48" ENSG00000168267 "Pancreas associated transcription factor 1a" Q7RTS3 10 23192312-23194245 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Diabetes mellitus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 47 "pancreas: 99.1" "Cell type enriched" "Detected in some" 4 "Pancreatic acinar cells: 130.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Pancreatic Adenocarcinoma (TCGA): 3.3" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Rhabdoid: 2.2" "Stomach - Gastric enteroendocrine cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB022612, HPA073033" Approved Nucleoplasm NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 5: Pancreatic acinar cells - Pancreatic exocrine secretion" 2 Nucleoplasm "CAB022612: , HPA073033: " "unprognostic (3.43e-1)" "unprognostic (9.94e-2)" "unprognostic (1.10e-3)" PTGDR "DP, DP1, PTGDR1" ENSG00000168229 "Prostaglandin D2 receptor" Q13258 14 52267698-52276724 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "Mast cell degranulation" "G-protein coupled receptor, Receptor, Transducer" "Asthma, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 7.4;lymphoid tissue: 5.9" "Cell type enhanced" "Detected in some" "Enteric stem cells: 48.1;Enteric transient amplifying cells: 34.6;Ependymal cells: 22.8;Innate lymphoid cells: 57.5;Medullary thymic epithelial cells: 16.8;NK-cells: 167.1;Platelets: 84.8;T-cells: 62.1" "Group enriched" "Detected in some" 4 "fibroblast: 129.4;leukocyte: 251.6" "Cancer enhanced" "Detected in some" "Colon Adenocarcinoma (TCGA): 1.9" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "gdT-cell: 68.2;MAIT T-cell: 33.5;memory CD8 T-cell: 40.9;naive CD8 T-cell: 22.6;NK-cell: 90.5" "Group enriched" "Detected in many" 33 "NK-cells: 90.5;T-cells: 68.2" "Cancer enhanced" "Detected in single" "Leukemia: 1.7" "Adipose visceral - T-cells, Adrenal gland - T-cells, Kidney - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Prostate - Fibroblasts, Thyroid gland - T-cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA046586, HPA049668" Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 17: Choroid plexus - Cilium" "Cluster 6: Leukemia - Signal transduction" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 5 "Plasma membrane, Cytosol" "HPA046586: , HPA049668: " "unprognostic (2.30e-2)" "unprognostic (2.76e-1)" "unprognostic (1.20e-2)" "unprognostic (1.83e-2)" "unprognostic (1.22e-1)" "unprognostic (2.73e-1)" "unprognostic (4.13e-2)" "unprognostic (5.36e-2)" PTGDR2 "CD294, CRTH2, DP2, GPR44" ENSG00000183134 "Prostaglandin D2 receptor 2" Q9Y5Y4 11 60850933-60855950 "CD markers, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 6.7;intestine: 8.0;skeletal muscle: 6.8;stomach 1: 8.8" "Cell type enhanced" "Detected in some" "cDC: 2.9;Fibroblasts: 2.9;Goblet cells: 2.2;Hematopoietic stem cells: 6.3;Innate lymphoid cells: 1.6;Mast cells: 2.9;Megakaryocyte-Erythroid progenitors: 2.6;Pancreatic islet cells: 2.6;Pericytes: 11.4;Vascular smooth muscle cells: 1.6" "Cell type enriched" "Detected in some" 6 "pericyte: 135.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "basophil: 178.8;eosinophil: 234.5" "Lineage enriched" "Detected in many" 7 "granulocytes: 234.5" "Cancer enriched" "Detected in single" 6 "Leukemia: 3.4" "Liver - Hepatocytes, Pancreas - Alpha cells, Pancreas - Beta cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA014259 Uncertain NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 52: Non-specific - Cellular respiration" "Cluster 47: Endothelial cells - Vasculature" "Cluster 59: Leukemia - T-cell receptor" "Cluster 22: Non-specific - Basic cellular functions" "HPA014259: " "unprognostic (6.76e-2)" "unprognostic (5.34e-3)" "unprognostic (1.05e-1)" "unprognostic (6.57e-3)" "unprognostic (4.03e-2)" PTGDS "L-PGDS, PGDS" ENSG00000107317 "Prostaglandin D2 synthase" P41222 9 136975092-136981742 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Mast cell degranulation, Prostaglandin biosynthesis, Prostaglandin metabolism, Transport" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 3337.6;heart muscle: 4605.2;testis: 3126.4" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 4382.1;Epididymal efferent duct absorptive cells: 4753.9;Epididymal principal cells: 6097.2;Leydig cells: 23234.4;Peritubular myoid cells: 43551.7;Retinal pigment epithelial cells: 8854.2" "Cell type enhanced" "Detected in all" "fibroblast: 3342.5;oligodendrocyte: 1969.6;pericyte: 1242.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 27 "plasmacytoid DC: 1389.8" "Lineage enriched" "Detected in many" 27 "dendritic cells: 1389.8" "Cancer enhanced" "Detected in many" "Bile duct cancer: 82.1" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Cardiomyocytes, Kidney - Podocytes, Liver - Hepatic stellate cells, Minor Salivary Gland - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "HPA004938, CAB009916, HPA067456" Uncertain "Secreted to blood" Transport NA NA 640000000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 94: Gonadal somatic cells - Mixed function" 19 "CAB009916: , HPA004938: , HPA067456: " "unprognostic (2.37e-2)" "unprognostic (7.18e-3)" "unprognostic (1.50e-2)" "unprognostic (2.87e-3)" "unprognostic (9.12e-2)" "unprognostic (1.30e-2)" "unprognostic (1.32e-1)" "unprognostic (6.82e-3)" "unprognostic (8.77e-3)" "unprognostic (5.42e-2)" "potential prognostic unfavorable (6.79e-4)" "unprognostic (6.36e-2)" "unprognostic (4.80e-2)" "unprognostic (4.32e-1)" "potential prognostic favorable (1.94e-4)" "potential prognostic favorable (1.14e-4)" "unprognostic (4.06e-2)" "unprognostic (3.41e-3)" "unprognostic (4.33e-1)" "unprognostic (2.69e-2)" "unprognostic (3.44e-1)" "unprognostic (1.83e-1)" "unprognostic (1.21e-1)" "unprognostic (8.77e-2)" "unprognostic (1.15e-1)" "unprognostic (4.24e-2)" "unprognostic (1.16e-1)" "unprognostic (5.90e-3)" "unprognostic (1.34e-1)" "unprognostic (2.14e-1)" "unprognostic (1.29e-1)" PTGER1 EP1 ENSG00000160951 "Prostaglandin E receptor 1" P34995 19 14472466-14475354 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "kidney: 26.2" "Cell type enhanced" "Detected in some" "Epicardial cells: 4.5;Megakaryocytes: 12.4;Oocytes: 4.6;Pericytes: 14.7;Renal collecting duct principal cells: 29.1;Renal connecting tubule cells: 7.7" "Cell type enhanced" "Detected in some" "pericyte: 3.0;vascular associated smooth muscle cell: 5.2" "Cancer enhanced" "Detected in some" "Ovary Serous Cystadenocarcinoma (TCGA): 5.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Neuroblastoma: 1.6" "Stomach - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 72: Kidney - Transmembrane transport" "Cluster 6: Non-specific - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" "unprognostic (6.87e-2)" "unprognostic (5.95e-2)" "unprognostic (1.18e-1)" "unprognostic (1.48e-1)" "unprognostic (3.34e-2)" "unprognostic (6.64e-2)" "unprognostic (2.42e-1)" "unprognostic (1.48e-1)" PTGER2 EP2 ENSG00000125384 "Prostaglandin E receptor 2" P43116 14 52314305-52328598 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 36.2" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 29.8;Endometrial secretory cells: 27.2;Gastric chief cells: 33.9;Hematopoietic stem cells: 24.7;Innate lymphoid cells: 29.7;Kupffer cells: 49.2;Megakaryocyte-Erythroid progenitors: 24.5;Monocyte progenitors: 30.4;monocytes: 98.4;Mucous neck cells: 43.7;Neutrophil progenitors: 49.1;Neutrophils: 29.3;NK-cells: 68.7;T-cells: 53.9" "Cell type enriched" "Detected in some" 12 "leukocyte: 55.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "choroid plexus: 6.4" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Heart muscle - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 15: Bone marrow - Innate immune response" "Cluster 8: Immune cells - Immune response" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" "unprognostic (1.18e-1)" "unprognostic (2.84e-1)" "unprognostic (4.29e-2)" "unprognostic (3.53e-2)" "unprognostic (7.24e-3)" "unprognostic (1.03e-1)" "unprognostic (8.48e-2)" "unprognostic (6.07e-2)" "potential prognostic unfavorable (7.49e-4)" "unprognostic (1.35e-1)" "unprognostic (9.36e-2)" "unprognostic (7.23e-3)" "unprognostic (1.33e-1)" "unprognostic (4.55e-2)" "unprognostic (1.31e-2)" "unprognostic (1.27e-1)" "unprognostic (2.95e-3)" "unprognostic (1.06e-1)" "unprognostic (2.21e-1)" "unprognostic (2.04e-2)" "unprognostic (2.56e-1)" "unprognostic (7.32e-2)" "unprognostic (2.64e-2)" "unprognostic (2.78e-2)" "unprognostic (1.12e-1)" "unprognostic (1.33e-1)" PTGER3 "EP3, lnc003875" ENSG00000050628 "Prostaglandin E receptor 3" P43115 1 70852353-71047816 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 81.4;kidney: 75.4;smooth muscle: 63.3" "Cell type enhanced" "Detected in many" "Adipocytes: 734.4;Distal convoluted tubule cells: 1008.5;Epididymal clear cells: 291.9;Loop of henle epithelial cells: 525.2;Mesothelial cells: 218.3;Parietal cells: 254.6;Renal collecting duct intercalated cells: 1517.2;Renal connecting tubule cells: 526.1;Respiratory ionocytes: 231.1" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 78.9;deep-layer near-projecting: 72.2;upper-layer intratelencephalic: 56.8" "Cancer enriched" "Detected in many" 7 "Kidney Chromophobe (TCGA): 204.3" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 62 "basophil: 40.2" "Lineage enriched" "Detected in single" 62 "granulocytes: 40.2" "Cancer enriched" "Detected in some" 6 "Bone cancer: 47.6" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Prostate - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010689 Uncertain NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 72: Kidney - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 3 "HPA010689: " "unprognostic (1.74e-1)" "unprognostic (9.66e-3)" "unprognostic (4.54e-1)" "unprognostic (1.15e-1)" "unprognostic (2.86e-2)" "unprognostic (5.74e-3)" "unprognostic (5.45e-2)" "validated prognostic favorable (3.54e-5)" "validated prognostic favorable (4.01e-4)" "potential prognostic unfavorable (2.47e-5)" "unprognostic (1.22e-2)" "unprognostic (3.40e-1)" "unprognostic (1.11e-1)" "unprognostic (1.90e-1)" "unprognostic (5.33e-3)" "unprognostic (7.73e-3)" "unprognostic (8.37e-2)" "unprognostic (3.58e-1)" "unprognostic (2.47e-1)" "unprognostic (6.57e-2)" "unprognostic (6.30e-3)" "unprognostic (6.33e-2)" "unprognostic (4.50e-3)" "unprognostic (2.43e-2)" PTGER4 EP4 ENSG00000171522 "Prostaglandin E receptor 4" P35408 5 40679915-40693735 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 81.0;pancreas: 51.1" "Cell type enhanced" "Detected in many" "cDC: 135.5;Foveolar cells: 89.1;Goblet cells: 76.8;Hematopoietic stem cells: 115.5;Innate lymphoid cells: 169.8;Kupffer cells: 84.0;Macrophages: 99.8;Mast cells: 73.5;monocytes: 79.7;Neutrophils: 104.6;NK-cells: 135.9;Podocytes: 143.8;T-cells: 218.1" "Cell type enriched" "Detected in many" 8 "leukocyte: 81.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Skeletal muscle - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA011226, HPA012756" Approved NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" 2 "HPA011226: , HPA012756: " "unprognostic (1.24e-2)" "unprognostic (3.25e-2)" "unprognostic (3.82e-2)" "unprognostic (4.88e-2)" "unprognostic (1.33e-2)" "unprognostic (1.29e-1)" "unprognostic (1.62e-1)" "unprognostic (1.85e-1)" "unprognostic (1.85e-1)" "unprognostic (8.56e-3)" "potential prognostic favorable (1.11e-4)" "unprognostic (7.15e-2)" "unprognostic (1.27e-1)" "unprognostic (1.58e-3)" "unprognostic (1.26e-1)" "unprognostic (1.09e-2)" "unprognostic (2.31e-2)" "unprognostic (2.61e-1)" "unprognostic (9.98e-2)" "unprognostic (1.16e-1)" "unprognostic (2.04e-2)" "unprognostic (9.01e-2)" "unprognostic (1.89e-1)" "unprognostic (2.97e-1)" "unprognostic (1.63e-2)" "unprognostic (1.23e-1)" "unprognostic (1.09e-1)" "unprognostic (1.66e-1)" "unprognostic (1.54e-2)" "unprognostic (2.50e-1)" "unprognostic (2.41e-1)" PTGES "MGST-IV, MGST1-L1, MGST1L1, PIG12, TP53I12" ENSG00000148344 "Prostaglandin E synthase" O14684 9 129738331-129753042 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Isomerase, Oxidoreductase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 79.5;urinary bladder: 73.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 144.4;Endometrial secretory cells: 73.9;Extravillous trophoblasts: 406.2;Migrating cytotrophoblasts: 326.9;Ocular epithelial cells: 120.5;Salivary duct cells: 118.5;Syncytiotrophoblasts: 317.6" "Cell type enriched" "Detected in some" 12 "endothelial cell: 25.0" "Cancer enhanced" "Detected in all" "Bladder Urothelial Carcinoma (TCGA): 121.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "basophil: 29.0" "Lineage enriched" "Detected in many" 7 "granulocytes: 29.0" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045064 Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 15 "Endoplasmic reticulum" "HPA045064: " "unprognostic (1.21e-2)" "unprognostic (6.20e-2)" "unprognostic (3.30e-1)" "unprognostic (2.97e-1)" "unprognostic (2.11e-2)" "unprognostic (7.99e-2)" "potential prognostic unfavorable (5.31e-4)" "unprognostic (5.44e-3)" "unprognostic (5.71e-2)" "unprognostic (1.02e-1)" "potential prognostic unfavorable (3.42e-5)" "unprognostic (2.16e-2)" "unprognostic (2.00e-1)" "unprognostic (4.64e-3)" "unprognostic (7.48e-3)" "potential prognostic unfavorable (6.68e-4)" "unprognostic (3.28e-2)" "unprognostic (1.80e-2)" "unprognostic (1.64e-1)" "unprognostic (1.49e-1)" "unprognostic (1.65e-1)" "potential prognostic unfavorable (5.87e-4)" "unprognostic (4.14e-3)" "unprognostic (2.40e-1)" "unprognostic (2.87e-2)" "unprognostic (4.23e-2)" "unprognostic (4.90e-2)" "unprognostic (1.17e-1)" "unprognostic (1.00e-1)" "unprognostic (1.61e-1)" "unprognostic (1.11e-1)" PTGES2 "C9orf15, FLJ14038" ENSG00000148334 "Prostaglandin E synthase 2" Q9H7Z7 9 128120693-128128462 "Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 131.0" "Cell type enhanced" "Detected in all" "Esophageal basal cells: 123.4;Gastric progenitor cells: 142.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020733 Approved NA No "Cluster 13: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cellular respiration" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 97: Non-specific - Cellular respiration" 23 "HPA020733: " "potential prognostic unfavorable (5.27e-7)" "unprognostic (7.86e-2)" "unprognostic (6.16e-2)" "unprognostic (6.20e-3)" "unprognostic (5.48e-2)" "unprognostic (3.88e-2)" "unprognostic (1.66e-2)" "unprognostic (1.11e-2)" "unprognostic (8.82e-2)" "unprognostic (3.11e-1)" "potential prognostic favorable (2.02e-4)" "unprognostic (1.20e-1)" "potential prognostic favorable (1.05e-4)" "potential prognostic unfavorable (5.49e-4)" "unprognostic (1.98e-3)" "unprognostic (6.00e-3)" "unprognostic (2.56e-1)" "unprognostic (2.08e-1)" "unprognostic (6.86e-2)" "unprognostic (5.67e-2)" "unprognostic (1.90e-1)" "unprognostic (1.55e-2)" "unprognostic (5.12e-2)" "unprognostic (3.24e-2)" "unprognostic (1.90e-1)" "unprognostic (2.20e-1)" "unprognostic (9.23e-2)" "unprognostic (1.36e-1)" "unprognostic (1.59e-1)" "unprognostic (2.48e-1)" "unprognostic (9.26e-2)" PTGES3 "cPGES, p23, TEBP" ENSG00000110958 "Prostaglandin E synthase 3" Q15185 12 56663341-56688408 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Chaperone, Isomerase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034319, HPA038672, HPA038673" Enhanced Approved Nucleoplasm,Cytosol NA NA 1300000 "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 75: Non-specific - Chaperones and protein folding" 201 Cytosol Nucleoplasm "CAB034319: , HPA038672: , HPA038673: " "unprognostic (3.39e-2)" "potential prognostic unfavorable (1.54e-4)" "unprognostic (1.17e-3)" "unprognostic (6.05e-3)" "unprognostic (7.34e-3)" "unprognostic (1.26e-1)" "unprognostic (1.70e-1)" "unprognostic (2.74e-3)" "unprognostic (5.45e-3)" "unprognostic (2.09e-2)" "potential prognostic favorable (1.14e-6)" "unprognostic (2.77e-2)" "unprognostic (2.96e-2)" "validated prognostic unfavorable (1.12e-4)" "validated prognostic unfavorable (6.54e-7)" "potential prognostic unfavorable (5.52e-5)" "unprognostic (1.91e-3)" "unprognostic (1.13e-1)" "unprognostic (1.26e-1)" "unprognostic (1.02e-1)" "unprognostic (2.51e-3)" "unprognostic (3.59e-3)" "unprognostic (1.83e-2)" "unprognostic (1.26e-3)" "unprognostic (7.87e-2)" "unprognostic (2.28e-2)" "unprognostic (7.05e-2)" "unprognostic (2.02e-1)" "unprognostic (2.81e-1)" "unprognostic (1.20e-1)" "unprognostic (4.77e-2)" PTGES3L ENSG00000267060 "Prostaglandin E synthase 3 like" E9PB15 17 42968088-42980433 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "skeletal muscle: 116.5;tongue: 88.6" "Cell type enhanced" "Detected in some" "Astrocytes: 1.5;Bergmann glia: 1.3;Brain excitatory neurons: 3.3;Brain inhibitory neurons: 6.0;Choroid plexus epithelial cells: 1.6;Ependymal cells: 3.0;Megakaryocytes: 6.2;Oligodendrocyte progenitor cells: 1.0;Other brain neurons: 3.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "plasmacytoid DC: 4.1" "Lineage enriched" "Detected in single" 6 "dendritic cells: 4.1" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Colon - Smooth muscle cells, Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Stomach - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 34: Non-specific - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 35: Neurons - Synaptic function & neurogenesis" "unprognostic (7.63e-2)" "unprognostic (2.00e-1)" "unprognostic (4.42e-3)" "unprognostic (5.50e-2)" "unprognostic (1.28e-1)" "unprognostic (9.36e-2)" "unprognostic (1.22e-1)" "unprognostic (3.44e-3)" "unprognostic (2.86e-1)" "unprognostic (2.71e-2)" "unprognostic (2.88e-3)" "unprognostic (1.03e-1)" "potential prognostic favorable (1.69e-4)" "unprognostic (5.75e-2)" "unprognostic (8.75e-3)" "unprognostic (1.84e-1)" "unprognostic (2.04e-2)" "unprognostic (1.33e-1)" "unprognostic (6.10e-2)" "unprognostic (3.92e-1)" "unprognostic (1.20e-1)" PTGES3L-AARSD1 ENSG00000108825 "PTGES3L-AARSD1 readthrough" Q9BTE6 17 42950526-42980528 "Predicted intracellular proteins" "Protein biosynthesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 16.4;tongue: 9.9" "Group enriched" "Detected in some" 11 "Adipocytes: 6.9;Cardiomyocytes: 23.8;Megakaryocytes: 6.2" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 3.5" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 16 "plasmacytoid DC: 1.5" "Lineage enriched" "Detected in single" 16 "dendritic cells: 1.5" "Low cancer specificity" "Detected in many" "HPA021408, HPA022869, HPA023714" Approved Approved "Nuclear membrane,Cytosol" NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 53: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" "Nuclear membrane, Cytosol" "HPA021408: , HPA022869: , HPA023714: " "unprognostic (6.52e-2)" "unprognostic (1.37e-1)" "unprognostic (1.18e-1)" "unprognostic (1.08e-1)" "unprognostic (2.30e-1)" "unprognostic (1.02e-2)" "unprognostic (2.35e-1)" "unprognostic (1.60e-3)" "unprognostic (1.36e-1)" "unprognostic (1.67e-1)" PTGFR FP ENSG00000122420 "Prostaglandin F receptor" P43088 1 78303884-78540701 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 18.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 158.3;Conjunctival goblet cells: 54.4;Distal convoluted tubule cells: 57.7;Fibro-adipogenic progenitors: 143.2;Fibroblasts: 73.3;Loop of henle epithelial cells: 79.3;Myonuclei: 38.1;Myosatellite cells: 53.1;Proximal tubule cells: 41.9;Renal collecting duct intercalated cells: 42.8;Renal connecting tubule cells: 66.9;Respiratory secretory cells: 63.5;Transitional alveolar cells: 36.5" "Cell type enhanced" "Detected in many" "fibroblast: 212.7;hippocampal dentate gyrus: 53.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 6.9;prostate cancer: 6.4" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Minor Salivary Gland - Fibroblasts, Prostate - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 29: Forebrain - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 1 "unprognostic (2.82e-2)" "unprognostic (4.05e-2)" "unprognostic (5.81e-2)" "unprognostic (1.52e-1)" "unprognostic (3.13e-2)" "unprognostic (2.12e-1)" "unprognostic (2.59e-2)" "unprognostic (3.34e-2)" "unprognostic (5.89e-2)" "unprognostic (1.62e-1)" "unprognostic (7.34e-2)" "unprognostic (1.13e-1)" "unprognostic (2.73e-1)" "unprognostic (2.12e-2)" "unprognostic (2.12e-1)" "unprognostic (2.30e-1)" "unprognostic (6.87e-2)" "unprognostic (1.30e-1)" "potential prognostic unfavorable (1.73e-4)" PTGFRN "CD315, CD9P-1, EWI-F, FLJ11001, FPRP, KIAA1436, SMAP-6" ENSG00000134247 "Prostaglandin F2 receptor inhibitor" Q9P2B2 1 116909916-116990353 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 115.6;Salivary basal cells: 91.9;Salivary myoepithelial cells: 140.2;Smooth muscle cells: 80.8" "Cell type enhanced" "Detected in many" "oligodendrocyte precursor cell: 60.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Breast - Breast myoepithelial cells, Colon - Smooth muscle cells, Lung - Fibroblasts_2, Skeletal muscle - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017074 Approved NA NA 320000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 26: Keratinocytes - Keratinization" 24 "HPA017074: " "unprognostic (3.85e-1)" "unprognostic (1.81e-1)" "unprognostic (4.49e-2)" "unprognostic (1.49e-3)" "unprognostic (3.07e-3)" "unprognostic (1.64e-1)" "unprognostic (3.11e-1)" "potential prognostic unfavorable (7.75e-4)" "unprognostic (7.28e-2)" "unprognostic (6.30e-3)" "unprognostic (8.44e-2)" "unprognostic (1.26e-1)" "unprognostic (3.25e-1)" "unprognostic (2.34e-3)" "unprognostic (1.69e-2)" "unprognostic (3.03e-3)" "unprognostic (6.88e-2)" "unprognostic (4.76e-2)" "unprognostic (8.73e-2)" "unprognostic (2.08e-1)" "unprognostic (1.05e-1)" "unprognostic (5.45e-2)" "unprognostic (2.78e-3)" "unprognostic (3.82e-1)" "unprognostic (1.76e-2)" "unprognostic (5.72e-2)" "unprognostic (1.69e-2)" "unprognostic (1.87e-1)" "unprognostic (1.72e-1)" "unprognostic (5.53e-2)" "unprognostic (2.76e-1)" PTGIR IP ENSG00000160013 "Prostaglandin I2 receptor" P43119 19 46620468-46625089 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 72.9;lung: 55.0" "Cell type enriched" "Detected in some" 4 "Platelets: 312.0" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 5.1;leukocyte: 5.2;vascular associated smooth muscle cell: 7.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 10 "classical monocyte: 28.3;intermediate monocyte: 65.3;myeloid DC: 20.9;non-classical monocyte: 38.9" "Group enriched" "Detected in many" 11 "dendritic cells: 20.9;monocytes: 65.3" "Cancer enhanced" "Detected in some" "Leukemia: 6.4;Neuroblastoma: 7.7" "Spleen - Fibroblasts_1, Testis - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 51: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 47: Platelets - Hemostasis" 6 "unprognostic (1.57e-1)" "unprognostic (2.42e-1)" "unprognostic (1.12e-1)" "unprognostic (6.03e-3)" "unprognostic (1.63e-2)" "unprognostic (1.78e-1)" "unprognostic (1.48e-1)" "unprognostic (4.84e-3)" "unprognostic (1.34e-2)" "unprognostic (1.53e-1)" "unprognostic (1.66e-2)" "unprognostic (1.28e-3)" "unprognostic (1.72e-1)" "unprognostic (1.68e-2)" "unprognostic (1.19e-2)" "unprognostic (5.97e-2)" "potential prognostic unfavorable (2.01e-4)" "unprognostic (2.89e-1)" "unprognostic (4.99e-2)" "unprognostic (1.10e-1)" "unprognostic (2.10e-1)" "unprognostic (1.18e-1)" "unprognostic (1.53e-1)" "unprognostic (1.24e-2)" "unprognostic (1.66e-1)" "unprognostic (3.17e-3)" "unprognostic (1.14e-3)" "unprognostic (3.21e-1)" "unprognostic (1.18e-1)" PTGIS "CYP8A1, PGIS" ENSG00000124212 "Prostaglandin I2 synthase" Q16647 20 49503874-49568137 "Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Isomerase, Lyase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 123.6" "Cell type enhanced" "Detected in many" "Epicardial cells: 161.5;Fibro-adipogenic progenitors: 237.0;Fibroblasts: 172.4;Hepatic stellate cells: 58.1;Leydig cells: 77.5;Mesothelial cells: 335.5;Ovarian stromal cells: 60.1;Peritubular myoid cells: 227.3;Smooth muscle cells: 205.2;Vascular endothelial cells: 84.8" "Cell type enhanced" "Detected in many" "fibroblast: 95.5;vascular associated smooth muscle cell: 54.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 16.7" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblasts_2, Pancreas - Fibroblasts, Prostate - Smooth muscle cells, Spleen - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009517, HPA014193, HPA052244" Enhanced Approved "Endoplasmic reticulum,Golgi apparatus,Cytosol" NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 1 "Endoplasmic reticulum" "Golgi apparatus, Cytosol" "CAB009517: , HPA014193: , HPA052244: " "unprognostic (4.67e-2)" "unprognostic (5.16e-2)" "unprognostic (4.77e-2)" "unprognostic (1.17e-2)" "unprognostic (3.25e-3)" "unprognostic (6.13e-2)" "unprognostic (1.05e-2)" "potential prognostic unfavorable (7.64e-4)" "unprognostic (1.25e-1)" "unprognostic (6.25e-2)" "unprognostic (3.21e-1)" "potential prognostic unfavorable (1.10e-5)" "unprognostic (6.37e-3)" "unprognostic (6.55e-2)" "unprognostic (4.31e-2)" "unprognostic (1.43e-1)" "unprognostic (1.78e-3)" "unprognostic (1.90e-1)" "unprognostic (1.34e-2)" "unprognostic (3.38e-3)" "unprognostic (2.27e-2)" "unprognostic (6.81e-2)" "unprognostic (8.30e-3)" "unprognostic (5.44e-3)" "unprognostic (6.03e-2)" "unprognostic (5.76e-3)" "unprognostic (5.01e-3)" "unprognostic (1.99e-1)" "unprognostic (4.23e-3)" "unprognostic (1.08e-1)" PTGR1 "LTB4DH, ZADH3" ENSG00000106853 "Prostaglandin reductase 1" Q14914 9 111549722-111599893 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Prostaglandin metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 262.5;liver: 555.5" "Cell type enhanced" "Detected in many" "Enterocytes: 1465.1;Esophageal suprabasal cells: 602.2;Hepatocytes: 1262.3;Papillary tip epithelial cells: 835.7;Renal collecting duct principal cells: 558.7;Suprabasal keratinocytes: 840.3;Urothelial cells: 1114.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "plasmacytoid DC: 6.0" "Lineage enriched" "Detected in single" 10 "dendritic cells: 6.0" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Spleen - Fibroblasts_1, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA036724 Enhanced NA NA 4600000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 29: Forebrain - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 69: Urothelial cells - Basic cellular functions" 2 "HPA036724: " "unprognostic (1.38e-1)" "unprognostic (5.48e-2)" "unprognostic (1.77e-1)" "unprognostic (4.32e-1)" "unprognostic (3.79e-2)" "unprognostic (1.70e-1)" "unprognostic (5.94e-2)" "potential prognostic unfavorable (7.33e-4)" "potential prognostic unfavorable (2.42e-4)" "unprognostic (1.45e-1)" "potential prognostic favorable (2.57e-6)" "unprognostic (8.24e-3)" "unprognostic (1.58e-1)" "unprognostic (4.07e-3)" "unprognostic (2.89e-1)" "unprognostic (6.04e-3)" "unprognostic (2.40e-1)" "unprognostic (2.50e-1)" "unprognostic (1.74e-1)" "unprognostic (7.08e-2)" "unprognostic (1.50e-1)" "unprognostic (9.64e-3)" "unprognostic (1.92e-1)" "unprognostic (2.84e-1)" "unprognostic (1.84e-3)" "unprognostic (1.53e-1)" "unprognostic (2.19e-1)" "unprognostic (4.07e-1)" "unprognostic (2.10e-1)" "unprognostic (8.66e-2)" "unprognostic (4.31e-2)" PTGR2 "FLJ39091, ZADH1" ENSG00000140043 "Prostaglandin reductase 2" Q8N8N7 14 73851831-73885726 "Enzymes, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 17.5;Bergmann glia: 22.2;Brain excitatory neurons: 12.5;Brain inhibitory neurons: 14.1;Choroid plexus epithelial cells: 36.6;Ependymal cells: 32.5;Microglia: 12.5;Oligodendrocyte progenitor cells: 12.3;Oligodendrocytes: 21.5;Other brain neurons: 12.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 6.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001125 Approved Approved Vesicles NA NA 32000 "Cluster 30: Non-specific - DNA binding" "Cluster 52: Non-specific - Cellular respiration" "Cluster 46: Brainstem - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 22: Non-specific - Basic cellular functions" 3 Vesicles "HPA001125: " "unprognostic (2.95e-1)" "unprognostic (1.97e-1)" "unprognostic (8.05e-2)" "unprognostic (3.05e-1)" "unprognostic (2.06e-1)" "unprognostic (3.28e-2)" "unprognostic (3.90e-1)" "unprognostic (1.83e-1)" "unprognostic (2.33e-1)" "unprognostic (2.47e-2)" "validated prognostic favorable (1.59e-8)" "validated prognostic favorable (6.34e-6)" "unprognostic (5.76e-3)" "unprognostic (1.48e-1)" "unprognostic (3.67e-2)" "unprognostic (3.95e-3)" "unprognostic (8.27e-2)" "potential prognostic favorable (2.64e-4)" "unprognostic (3.68e-2)" "unprognostic (1.10e-1)" "unprognostic (2.70e-2)" "unprognostic (1.47e-1)" "unprognostic (7.59e-3)" "unprognostic (6.25e-2)" "unprognostic (3.64e-1)" "unprognostic (4.79e-1)" "unprognostic (1.15e-1)" "unprognostic (8.86e-3)" "unprognostic (2.29e-1)" "unprognostic (2.88e-1)" "unprognostic (5.53e-3)" PTGR3 "MGC45594, PTGR-3, ZADH2" ENSG00000180011 "Prostaglandin reductase 3" Q8N4Q0 18 75195113-75209139 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021468, HPA053646" Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 37: Neurons - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 108: Fibroblasts - ECM organization" 8 Vesicles "Nucleoplasm, Golgi apparatus" "HPA021468: , HPA053646: " "unprognostic (4.72e-1)" "unprognostic (3.25e-2)" "unprognostic (3.84e-1)" "unprognostic (2.29e-1)" "unprognostic (7.22e-2)" "unprognostic (1.45e-1)" "unprognostic (2.32e-1)" "unprognostic (1.49e-3)" "unprognostic (2.00e-2)" "unprognostic (1.54e-1)" "validated prognostic favorable (3.82e-6)" "validated prognostic favorable (7.88e-5)" "unprognostic (1.70e-2)" "unprognostic (9.51e-2)" "unprognostic (2.69e-1)" "unprognostic (2.21e-1)" "unprognostic (1.56e-1)" "unprognostic (4.06e-1)" "unprognostic (2.26e-1)" "unprognostic (9.87e-2)" "unprognostic (2.65e-1)" "unprognostic (5.87e-2)" "unprognostic (7.45e-2)" "unprognostic (5.39e-2)" "unprognostic (1.29e-1)" "unprognostic (4.53e-2)" "unprognostic (2.94e-3)" "unprognostic (1.88e-1)" "unprognostic (1.37e-1)" "unprognostic (1.39e-3)" "unprognostic (2.69e-1)" PTGS1 "COX1, PGHS-1, PTGHS" ENSG00000095303 "Prostaglandin-endoperoxide synthase 1" P23219 9 122370530-122395703 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Dioxygenase, Oxidoreductase, Peroxidase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 102.0;skin 1: 144.0;urinary bladder: 227.5" "Cell type enhanced" "Detected in many" "Endometrial luminal cells: 498.1;Mast cells: 219.5;Megakaryocytes: 284.4;Platelets: 1502.3;Smooth muscle cells: 174.0;Tuft cells: 795.4" "Cell type enriched" "Detected in some" 8 "central nervous system macrophage: 109.6" "Cancer enhanced" "Detected in all" "Ovary Serous Cystadenocarcinoma (TCGA): 85.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 28.8" "Group enriched" "Detected in many" 6 "dendritic cells: 20.0;granulocytes: 28.8;monocytes: 13.1" "Cancer enhanced" "Detected in many" "cervical cancer: 32.5;ovarian cancer: 30.4" "Adrenal gland - Macrophages, Skeletal muscle - Fibroblasts, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA002834, CAB020315" Enhanced Uncertain "Golgi apparatus,Vesicles" "Intracellular and membrane" Enzyme NA NA 850000 "Cluster 29: Non-specific - Unknown function" "Cluster 58: Skin - Keratinization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 4 "Golgi apparatus, Vesicles" "CAB020315: , HPA002834: " "unprognostic (4.58e-3)" "unprognostic (2.00e-1)" "unprognostic (3.75e-1)" "unprognostic (5.37e-2)" "unprognostic (5.62e-2)" "unprognostic (3.35e-2)" "unprognostic (3.47e-2)" "unprognostic (1.37e-1)" "unprognostic (3.64e-2)" "unprognostic (2.55e-1)" "unprognostic (9.07e-2)" "unprognostic (2.81e-1)" "unprognostic (4.94e-2)" "unprognostic (4.62e-3)" "unprognostic (2.30e-2)" "unprognostic (1.41e-2)" "unprognostic (1.26e-2)" "unprognostic (4.20e-2)" "unprognostic (1.75e-2)" "unprognostic (1.81e-1)" "unprognostic (3.47e-2)" "unprognostic (2.41e-1)" "unprognostic (4.25e-1)" "unprognostic (9.27e-2)" "unprognostic (4.02e-2)" "unprognostic (1.36e-1)" "unprognostic (5.52e-2)" "unprognostic (3.79e-2)" "unprognostic (1.74e-2)" "unprognostic (3.57e-1)" "unprognostic (1.28e-2)" PTGS2 COX2 ENSG00000073756 "Prostaglandin-endoperoxide synthase 2" P35354 1 186671791-186680922 "Cancer-related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Dioxygenase, Oxidoreductase, Peroxidase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 110.4;seminal vesicle: 120.2;urinary bladder: 151.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 296.2;Epididymal basal cells: 666.1;Fibroblasts: 184.6;Mast cells: 391.0;monocytes: 659.0;Neutrophils: 1508.5;Ocular epithelial cells: 381.7;Urothelial cells: 450.9" "Cell type enriched" "Detected in many" 7 "endothelial cell: 100.5" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 34.5" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 16 "neutrophil: 11.8" "Lineage enriched" "Detected in single" 16 "granulocytes: 11.8" "Low cancer specificity" "Detected in many" "Stomach - Fibroblasts" "Region enhanced" "Detected in many" "hippocampal formation: 15.1" "Low region specificity" "Detected in all" "CAB000113, HPA001335, CAB080135" Enhanced Supported Vesicles,Cytosol "Intracellular and membrane" Enzyme NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 53: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 10 Vesicles Cytosol "CAB000113: , CAB080135: , HPA001335: " "unprognostic (3.09e-2)" "unprognostic (3.75e-3)" "unprognostic (5.70e-2)" "unprognostic (2.33e-2)" "unprognostic (6.91e-3)" "unprognostic (1.24e-1)" "unprognostic (5.25e-2)" "potential prognostic unfavorable (7.31e-4)" "unprognostic (1.27e-1)" "unprognostic (2.84e-1)" "unprognostic (2.59e-1)" "unprognostic (1.14e-2)" "unprognostic (1.01e-2)" "unprognostic (1.82e-2)" "unprognostic (2.14e-1)" "unprognostic (2.30e-1)" "unprognostic (1.88e-1)" "unprognostic (2.72e-1)" "unprognostic (1.75e-1)" "unprognostic (9.67e-3)" "unprognostic (5.46e-2)" "unprognostic (1.51e-1)" "unprognostic (2.86e-1)" "unprognostic (3.59e-1)" "unprognostic (2.08e-2)" "unprognostic (2.77e-2)" "unprognostic (1.53e-1)" "unprognostic (6.14e-2)" PTH PTH1 ENSG00000152266 "Parathyroid hormone" P01270 11 13492054-13496181 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" Hormone "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8703 "parathyroid gland: 47154.2" "Cell type enhanced" "Detected in some" "Epididymal clear cells: 2.0;Foveolar cells: 5.4;Gastric chief cells: 2.2;Mucous neck cells: 2.8;Paneth cells: 3.9;Parietal cells: 8.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB000072, CAB023409, CAB026363, HPA048540" Enhanced "Secreted to blood" Hormone NA NA 28000 "Cluster 69: Parathyroid gland - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 97: Non-specific - Cellular respiration" 3 "CAB000072: , CAB023409: , CAB026363: , HPA048540: " PTH1R "PTHR, PTHR1" ENSG00000160801 "Parathyroid hormone 1 receptor" Q03431 3 46877721-46903799 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "kidney: 583.6" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 339.1;Extravillous trophoblasts: 123.9;Hepatic stellate cells: 142.0;Loop of henle epithelial cells: 236.9;Pericytes: 138.9;Podocytes: 1120.4;Proximal tubule cells: 1001.2;Renal connecting tubule cells: 193.8" "Cell type enriched" "Detected in many" 6 "pericyte: 798.2" "Cancer enriched" "Detected in many" 6 "Kidney Renal Papillary Cell Carcinoma (TCGA): 141.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 4.8" "Breast - Adipocytes (Breast), Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007491, HPA075879" Enhanced Supported "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 47: Endothelial cells - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 88: Proximal tubular cells - Transmembrane transport" 16 "Plasma membrane, Cytosol" Nucleoli "HPA007491: , HPA075879: " "unprognostic (2.48e-2)" "unprognostic (2.20e-1)" "unprognostic (1.06e-1)" "unprognostic (4.40e-2)" "unprognostic (2.32e-1)" "unprognostic (2.94e-1)" "unprognostic (2.00e-2)" "unprognostic (1.03e-1)" "validated prognostic favorable (2.29e-5)" "validated prognostic favorable (3.76e-4)" "potential prognostic favorable (4.34e-4)" "unprognostic (1.08e-2)" "potential prognostic favorable (5.61e-4)" "unprognostic (7.69e-2)" "unprognostic (5.46e-2)" "unprognostic (2.25e-2)" "unprognostic (2.42e-1)" "unprognostic (2.97e-2)" "unprognostic (3.60e-2)" "unprognostic (8.41e-2)" "unprognostic (3.15e-1)" "unprognostic (1.59e-2)" "unprognostic (4.15e-2)" "unprognostic (1.81e-1)" "potential prognostic unfavorable (5.38e-5)" "unprognostic (9.26e-2)" PTH2 TIP39 ENSG00000142538 "Parathyroid hormone 2" Q96A98 19 49422419-49423441 "Predicted secreted proteins" Neuropeptide "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.0" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 2.1;Early primary spermatocytes: 2.0;Early spermatids: 1.7;Innate lymphoid cells: 14.0;Late primary spermatocytes: 3.5;Late spermatids: 4.0;Megakaryocytes: 6.2;Müller glia: 1.9;Oocytes: 9.2" "Cell type enriched" "Detected in some" 5 "thalamic excitatory: 13.5" "Not detected" "Not detected" "Region enhanced" "Detected in many" "midbrain: 7.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Rhabdoid: 1.0" "Region enriched" "Detected in single" 10 "olfactory bulb: 2.9" "Low region specificity" "Detected in all" "Secreted in brain" Neuropeptide NA NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 2: Neurons - Nucleosome" "Cluster 6: Leukemia - Signal transduction" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 1 PTH2R PTHR2 ENSG00000144407 "Parathyroid hormone 2 receptor" P49190 2 208359714-208854503 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.1;retina: 15.2" "Group enriched" "Detected in many" 4 "Distal convoluted tubule cells: 1640.6;Loop of henle epithelial cells: 931.4;Proximal tubule cells: 3087.2;Renal connecting tubule cells: 1471.3" "Cell type enhanced" "Detected in many" "hippocampal dentate gyrus: 95.4" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 7.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA010655 Approved NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 47: Leukemia - Hemostasis" "Cluster 88: Proximal tubular cells - Transmembrane transport" 2 "HPA010655: " "unprognostic (3.18e-2)" "unprognostic (6.69e-3)" "unprognostic (1.55e-1)" "unprognostic (1.27e-2)" "unprognostic (2.14e-1)" "unprognostic (8.27e-2)" "unprognostic (2.09e-2)" "unprognostic (1.69e-1)" "unprognostic (1.74e-2)" "unprognostic (1.43e-1)" "unprognostic (5.56e-2)" "unprognostic (1.10e-1)" "unprognostic (5.74e-2)" "unprognostic (3.28e-2)" "unprognostic (1.52e-1)" PTHLH "HHM, PLP, PTHR, PTHRP" ENSG00000087494 "Parathyroid hormone like hormone" P12272 12 27958084-27972733 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" Hormone "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 21.4" "Group enriched" "Detected in many" 8 "Breast hormone-responsive cells: 155.1;Breast lactating cells: 423.4" "Group enriched" "Detected in many" 4 "cerebellar inhibitory: 20.1;CGE interneuron: 45.9;LAMP5-LHX6 and Chandelier: 49.8" "Cancer enhanced" "Detected in all" "Head and Neck Squamous Cell Carcinoma (TCGA): 267.6;Lung Squamous Cell Carcinoma (TCGA): 231.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 243.3" "Colon - Enteric glia cells, Skeletal muscle - Fibroblasts, Skin - Outer root sheath cells, Testis - Early spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035982 Approved Approved Supported "Nucleoplasm,Golgi apparatus,Cytosol" "Secreted in other tissues" Hormone NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 4: Breast lactating luminal cells - Lactation" 5 "Nucleoplasm, Cytosol" "Golgi apparatus" "HPA035982: " "unprognostic (3.52e-2)" "unprognostic (2.40e-1)" "unprognostic (9.06e-2)" "unprognostic (1.69e-2)" "unprognostic (3.17e-1)" "unprognostic (2.38e-2)" "unprognostic (3.37e-1)" "unprognostic (2.18e-1)" "unprognostic (9.76e-2)" "potential prognostic unfavorable (3.52e-4)" "potential prognostic unfavorable (1.92e-4)" "unprognostic (3.73e-3)" "potential prognostic unfavorable (4.19e-6)" "unprognostic (2.37e-3)" "unprognostic (1.21e-1)" "unprognostic (1.36e-2)" "unprognostic (1.01e-1)" "unprognostic (4.70e-2)" "unprognostic (3.84e-1)" "unprognostic (1.79e-1)" "unprognostic (1.26e-1)" "unprognostic (4.80e-3)" "unprognostic (7.93e-3)" "unprognostic (1.62e-1)" "unprognostic (2.72e-1)" "unprognostic (6.09e-3)" "unprognostic (2.83e-2)" "unprognostic (1.54e-2)" "unprognostic (2.66e-1)" "unprognostic (4.23e-3)" "unprognostic (1.01e-1)" PTK2 "FADK, FAK, FAK1, PPP1R71" ENSG00000169398 "Protein tyrosine kinase 2" Q05397 8 140657900-141002216 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Angiogenesis "Developmental protein, Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 1291.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skin - Endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001842, CAB004036, HPA029671" Approved Supported "Vesicles,Focal adhesion sites,Primary cilium,Primary cilium tip,Cytosol" NA Yes 4600 "Cluster 34: B-cells - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 40: Non-specific - Unknown function" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 110 "Focal adhesion sites" "Vesicles, Primary cilium, Primary cilium tip, Cytosol" "CAB004036: , HPA001842: , HPA029671: " "unprognostic (1.35e-1)" "potential prognostic unfavorable (9.28e-4)" "unprognostic (1.49e-1)" "unprognostic (5.54e-3)" "unprognostic (1.29e-1)" "unprognostic (5.58e-3)" "unprognostic (1.61e-1)" "unprognostic (1.19e-3)" "unprognostic (1.17e-1)" "potential prognostic unfavorable (1.25e-5)" "validated prognostic favorable (2.39e-5)" "validated prognostic favorable (1.27e-4)" "unprognostic (1.97e-2)" "unprognostic (2.98e-2)" "unprognostic (1.81e-2)" "unprognostic (1.19e-1)" "unprognostic (3.19e-2)" "unprognostic (5.09e-2)" "unprognostic (2.21e-1)" "unprognostic (9.65e-2)" "unprognostic (2.62e-1)" "unprognostic (3.61e-2)" "potential prognostic unfavorable (7.77e-5)" "unprognostic (5.46e-1)" "unprognostic (7.22e-2)" "unprognostic (1.79e-1)" "unprognostic (2.11e-1)" "unprognostic (2.13e-2)" "unprognostic (6.75e-2)" "unprognostic (3.12e-1)" "unprognostic (7.90e-2)" PTK2B "CADTK, CAKB, FAK2, PTK, PYK2, RAFTK" ENSG00000120899 "Protein tyrosine kinase 2 beta" Q14289 8 27311482-27459391 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Adaptive immunity, Angiogenesis, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 100.4;brain: 136.7" "Cell type enhanced" "Detected in many" "Monocyte progenitors: 405.5;monocytes: 590.0;Neutrophil progenitors: 771.7;Neutrophils: 1387.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Leukemia: 122.9;lymphoma: 76.7;Myeloma: 126.4;prostate cancer: 37.4" "Heart muscle - Macrophages, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003850, HPA026091, HPA026276" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 27: Cerebellum - Synaptic function" "Cluster 51: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 37 "Plasma membrane, Cytosol" "CAB003850: , HPA026091: , HPA026276: " "unprognostic (4.51e-3)" "unprognostic (2.35e-1)" "potential prognostic favorable (4.22e-4)" "unprognostic (2.95e-2)" "unprognostic (1.47e-2)" "unprognostic (6.36e-2)" "unprognostic (1.15e-1)" "unprognostic (2.90e-2)" "unprognostic (2.61e-2)" "unprognostic (8.43e-2)" "unprognostic (1.17e-2)" "unprognostic (8.52e-2)" "unprognostic (6.87e-2)" "unprognostic (1.00e-1)" "potential prognostic favorable (9.18e-4)" "unprognostic (4.80e-3)" "unprognostic (1.02e-1)" "unprognostic (1.70e-1)" "unprognostic (8.71e-2)" "unprognostic (5.89e-2)" "unprognostic (2.65e-2)" "unprognostic (1.53e-2)" "unprognostic (5.51e-3)" "unprognostic (3.45e-1)" "unprognostic (7.39e-2)" "unprognostic (2.10e-2)" "unprognostic (2.04e-1)" "unprognostic (2.08e-1)" "unprognostic (4.79e-2)" "unprognostic (1.31e-2)" "unprognostic (2.58e-1)" PTK6 BRK ENSG00000101213 "Protein tyrosine kinase 6" Q13882 20 63528001-63537376 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 104.2;skin 1: 51.4;vagina: 41.0" "Cell type enriched" "Detected in many" 4 "Esophageal apical cells: 774.1" "Cell type enhanced" "Detected in single" "oligodendrocyte: 2.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.3" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 34.3" "Colon - Colon enterocytes, Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Urothelial cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB032952, HPA036070, HPA036071" Approved Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 41 Nucleoplasm "Nuclear bodies, Plasma membrane, Cytosol" "CAB032952: , HPA036070: , HPA036071: " "potential prognostic favorable (3.07e-4)" "unprognostic (7.89e-3)" "unprognostic (1.21e-1)" "unprognostic (1.82e-2)" "unprognostic (1.34e-1)" "unprognostic (2.94e-2)" "unprognostic (1.46e-1)" "potential prognostic unfavorable (7.01e-8)" "unprognostic (2.01e-2)" "unprognostic (1.92e-1)" "unprognostic (1.26e-1)" "unprognostic (8.62e-2)" "unprognostic (2.96e-1)" "unprognostic (5.11e-2)" "unprognostic (1.43e-2)" "unprognostic (1.59e-2)" "unprognostic (4.69e-2)" "unprognostic (2.97e-1)" "potential prognostic unfavorable (2.73e-4)" "unprognostic (2.86e-2)" "unprognostic (7.93e-2)" "unprognostic (3.28e-1)" "unprognostic (1.56e-1)" "unprognostic (3.75e-2)" "unprognostic (1.83e-2)" "unprognostic (1.61e-1)" PTK7 CCK4 ENSG00000112655 "Protein tyrosine kinase 7 (inactive)" Q13308 6 43076307-43161719 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Wnt signaling pathway" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 184.2;Early spermatids: 424.1;Endometrial stromal cells: 165.1;Retinal ganglion cells: 139.1" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 104.3;fibroblast: 99.5" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "choroid plexus: 68.9" "Immune cell enriched" "Detected in some" 10 "plasmacytoid DC: 13.5" "Lineage enriched" "Detected in many" 10 "dendritic cells: 13.5" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Fibroblasts, Skeletal muscle - Fibroblasts, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003222 Approved Approved "Vesicles,Plasma membrane,Cytosol" "Secreted to blood" Receptor NA NA 5600000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 36: Choroid plexus - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 22 "Plasma membrane, Cytosol" Vesicles "HPA003222: " "unprognostic (2.72e-1)" "unprognostic (1.79e-1)" "unprognostic (4.56e-1)" "potential prognostic unfavorable (2.16e-4)" "unprognostic (2.54e-1)" "unprognostic (2.23e-1)" "unprognostic (1.39e-1)" "unprognostic (8.45e-2)" "unprognostic (1.47e-2)" "unprognostic (9.87e-3)" "unprognostic (1.83e-1)" "unprognostic (2.81e-2)" "unprognostic (1.53e-1)" "unprognostic (1.57e-2)" "unprognostic (3.60e-1)" "unprognostic (4.86e-2)" "unprognostic (1.77e-1)" "unprognostic (1.12e-1)" "unprognostic (8.48e-2)" "unprognostic (1.01e-1)" "unprognostic (1.69e-1)" "unprognostic (2.23e-2)" "unprognostic (1.25e-2)" "unprognostic (8.50e-2)" "unprognostic (2.00e-1)" "unprognostic (4.57e-3)" "unprognostic (1.83e-3)" "unprognostic (1.10e-1)" "unprognostic (3.81e-1)" "unprognostic (2.25e-1)" "unprognostic (1.58e-1)" PTMA TMSA ENSG00000187514 "Prothymosin alpha" P06454 2 231706895-231713551 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047183 Approved Enhanced Nucleoplasm,Cytosol No No 4700000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 54: Non-specific - Ribosome" "Cluster 11: White matter - Signal transduction" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 15: Non-specific - Protein processing" 38 Nucleoplasm Cytosol "HPA047183: " "unprognostic (1.46e-1)" "unprognostic (1.06e-2)" "unprognostic (1.89e-1)" "unprognostic (5.21e-3)" "unprognostic (1.15e-1)" "unprognostic (9.09e-2)" "unprognostic (5.16e-3)" "unprognostic (1.03e-3)" "unprognostic (3.45e-2)" "unprognostic (4.39e-2)" "unprognostic (2.60e-1)" "unprognostic (3.42e-2)" "unprognostic (1.13e-2)" "validated prognostic unfavorable (2.49e-5)" "validated prognostic unfavorable (3.07e-5)" "unprognostic (1.02e-2)" "unprognostic (1.10e-2)" "unprognostic (5.95e-2)" "unprognostic (3.33e-1)" "unprognostic (2.57e-2)" "unprognostic (1.81e-1)" "potential prognostic unfavorable (8.53e-4)" "unprognostic (6.18e-2)" "unprognostic (4.23e-2)" "unprognostic (1.10e-1)" "unprognostic (3.28e-2)" "unprognostic (5.99e-2)" "unprognostic (8.57e-2)" "unprognostic (1.48e-1)" "unprognostic (1.29e-1)" "unprognostic (2.25e-1)" PTMS ParaT ENSG00000159335 Parathymosin P20962 12 6765516-6770952 "Essential proteins, Predicted intracellular proteins" Immunity "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 760.4" "Cell type enhanced" "Detected in many" "Hepatocytes: 742.8;Hofbauer cells: 876.3;Megakaryocytes: 605.8;Peritubular myoid cells: 615.6;Smooth muscle cells: 619.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "basophil: 25.8" "Lineage enriched" "Detected in many" 6 "granulocytes: 25.8" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038186 Approved Approved "Nucleoplasm,Nucleoli,Nucleoli rim" No Yes 1600000 "Cluster 22: Eosinophils - Transcription" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 33: Neurons - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 94: Gonadal somatic cells - Mixed function" 4 "Nucleoli, Nucleoli rim" Nucleoplasm "HPA038186: " "unprognostic (5.52e-2)" "unprognostic (1.54e-2)" "unprognostic (5.69e-2)" "unprognostic (7.56e-2)" "unprognostic (1.43e-1)" "unprognostic (8.58e-2)" "unprognostic (1.47e-1)" "unprognostic (6.92e-3)" "unprognostic (6.18e-2)" "unprognostic (1.43e-2)" "unprognostic (1.55e-1)" "unprognostic (4.62e-2)" "unprognostic (1.20e-2)" "unprognostic (1.45e-1)" "unprognostic (2.78e-1)" "unprognostic (2.13e-1)" "unprognostic (3.11e-1)" "unprognostic (1.14e-1)" "unprognostic (8.34e-2)" "unprognostic (8.48e-2)" "unprognostic (3.89e-2)" "unprognostic (2.19e-3)" "unprognostic (3.65e-2)" "unprognostic (1.94e-1)" "unprognostic (1.00e-2)" "unprognostic (2.29e-1)" "unprognostic (4.53e-1)" "unprognostic (1.34e-1)" "unprognostic (9.69e-2)" "unprognostic (1.64e-2)" "unprognostic (6.76e-2)" PTN "HBGF8, HBNF, NEGF1" ENSG00000105894 Pleiotrophin P21246 7 137227341-137343774 "Cancer-related genes, Predicted secreted proteins" "Growth factor, Heparin-binding, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 251.8;parathyroid gland: 366.1" "Cell type enhanced" "Detected in many" "Bergmann glia: 1067.9;Breast secretory cells: 1817.3;Corticotrophs: 947.1;Endometrial stromal cells: 575.4;Esophageal basal cells: 476.7;Esophageal suprabasal cells: 791.0;Extravillous trophoblasts: 831.0;Migrating cytotrophoblasts: 433.0;Müller glia: 473.3;Oligodendrocyte progenitor cells: 523.8;Retinal horizontal cells: 530.9" "Cell type enhanced" "Detected in all" "Bergmann glia: 1231.5;fibroblast: 1570.4;pericyte: 1366.0" "Cancer enriched" "Detected in all" 12 "Glioblastoma Multiforme (TCGA): 1035.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 134.7;Neuroblastoma: 73.5" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Pituitary gland - Thyrotropes, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017685, HPA073913" Enhanced Supported "Endoplasmic reticulum" "Secreted to blood" "Growth factor" NA NA 167000 56000000 "Cluster 73: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 72: Neuronal - Signal transduction" "Cluster 85: Squamous epithelial cells - Keratinization" 22 "Endoplasmic reticulum" "CAB017685: , HPA073913: " "unprognostic (2.06e-1)" "unprognostic (2.63e-2)" "unprognostic (1.90e-2)" "unprognostic (8.00e-3)" "unprognostic (8.05e-2)" "unprognostic (1.30e-1)" "unprognostic (3.81e-1)" "unprognostic (1.02e-3)" "unprognostic (7.03e-2)" "unprognostic (6.73e-2)" "unprognostic (1.19e-2)" "unprognostic (5.28e-2)" "potential prognostic favorable (9.80e-5)" "unprognostic (3.82e-2)" "unprognostic (3.07e-3)" "unprognostic (2.48e-1)" "unprognostic (6.98e-3)" "unprognostic (8.13e-3)" "unprognostic (4.10e-1)" "unprognostic (2.82e-2)" "unprognostic (3.70e-2)" "unprognostic (2.89e-1)" "unprognostic (3.69e-1)" "unprognostic (6.31e-2)" "unprognostic (2.36e-2)" "unprognostic (4.06e-2)" "unprognostic (2.13e-2)" "unprognostic (1.15e-1)" "unprognostic (1.51e-1)" "unprognostic (4.14e-2)" "unprognostic (4.08e-2)" PTOV1 ENSG00000104960 "PTOV1 extended AT-hook containing adaptor protein" Q86YD1 19 49850735-49860744 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 386.7;Late spermatids: 1068.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051812, HPA075125" Approved Supported Nucleoplasm NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 21 Nucleoplasm "HPA051812: , HPA075125: " "unprognostic (4.25e-2)" "unprognostic (3.18e-1)" "unprognostic (8.82e-2)" "unprognostic (1.69e-1)" "unprognostic (3.29e-1)" "unprognostic (4.15e-2)" "unprognostic (1.60e-1)" "unprognostic (1.18e-1)" "unprognostic (2.13e-1)" "unprognostic (2.27e-1)" "unprognostic (5.24e-2)" "unprognostic (5.12e-2)" "unprognostic (3.10e-3)" "potential prognostic unfavorable (4.79e-4)" "unprognostic (1.30e-1)" "unprognostic (1.46e-2)" "unprognostic (2.28e-1)" "unprognostic (4.06e-1)" "unprognostic (3.44e-1)" "unprognostic (9.08e-2)" "unprognostic (1.20e-1)" "unprognostic (8.17e-3)" "unprognostic (2.34e-3)" "unprognostic (1.15e-1)" "unprognostic (2.59e-1)" "unprognostic (9.67e-2)" "unprognostic (2.72e-1)" "unprognostic (1.68e-1)" "unprognostic (7.38e-3)" "unprognostic (1.34e-1)" "unprognostic (1.60e-1)" PTP4A1 "PRL-1, PRL1, PTPCAAX1" ENSG00000112245 "Protein tyrosine phosphatase 4A1" Q93096 6 63521746-63583588 "Enzymes, Predicted intracellular proteins" "Cell cycle" "Developmental protein, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 533.7;skeletal muscle: 349.2" "Cell type enhanced" "Detected in many" "Breast lactating cells: 28.1;Ependymal cells: 34.1;Fallopian tube ciliated cells: 28.5;Hepatocytes: 32.0;Loop of henle epithelial cells: 26.9;Myonuclei: 81.9;Papillary tip epithelial cells: 30.5;Renal collecting duct principal cells: 41.1;Renal connecting tubule cells: 35.6;Salivary acinar cells: 98.8;Salivary myoepithelial cells: 31.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA003281 Approved NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 55: Myocytes - Oxidative muscle function" 25 "HPA003281: " "unprognostic (1.46e-2)" "unprognostic (2.21e-2)" "unprognostic (1.37e-2)" "unprognostic (2.13e-3)" "unprognostic (1.82e-2)" "unprognostic (1.53e-1)" "unprognostic (1.87e-1)" "unprognostic (4.07e-2)" "unprognostic (3.77e-2)" "unprognostic (3.18e-1)" "potential prognostic favorable (4.94e-5)" "unprognostic (5.15e-2)" "potential prognostic unfavorable (7.91e-4)" "unprognostic (2.76e-1)" "unprognostic (4.11e-2)" "unprognostic (1.13e-1)" "unprognostic (2.17e-1)" "unprognostic (1.76e-1)" "unprognostic (3.38e-1)" "unprognostic (1.20e-1)" "unprognostic (2.07e-2)" "unprognostic (5.50e-3)" "unprognostic (6.58e-3)" "unprognostic (1.33e-2)" "unprognostic (2.78e-1)" "unprognostic (2.30e-1)" "unprognostic (1.52e-1)" "unprognostic (3.98e-2)" "unprognostic (2.23e-1)" "unprognostic (1.18e-2)" "unprognostic (2.00e-1)" PTP4A2 "HU-PP-1, OV-1, PRL-2, PRL2, ptp-IV1a, PTP4A, PTPCAAX2" ENSG00000184007 "Protein tyrosine phosphatase 4A2" Q12974 1 31906421-31944856 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 280.8;Platelets: 485.6;Urothelial cells: 326.6" "Cell type enhanced" "Detected in all" "leukocyte: 124.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003281, CAB011204" Uncertain NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 59: Leukemia - T-cell receptor" "Cluster 69: Urothelial cells - Basic cellular functions" 23 "CAB011204: , HPA003281: " "unprognostic (7.12e-2)" "unprognostic (1.91e-1)" "unprognostic (7.40e-3)" "unprognostic (1.10e-2)" "unprognostic (2.63e-3)" "unprognostic (2.21e-2)" "unprognostic (5.42e-2)" "unprognostic (3.58e-1)" "unprognostic (1.44e-1)" "potential prognostic unfavorable (5.50e-5)" "unprognostic (1.96e-3)" "unprognostic (1.44e-1)" "unprognostic (3.36e-2)" "validated prognostic unfavorable (4.67e-7)" "validated prognostic unfavorable (2.31e-6)" "unprognostic (7.13e-3)" "unprognostic (3.97e-2)" "unprognostic (1.07e-3)" "unprognostic (1.54e-1)" "unprognostic (2.06e-3)" "unprognostic (4.10e-1)" "unprognostic (2.58e-2)" "unprognostic (2.15e-1)" "unprognostic (2.86e-2)" "unprognostic (4.15e-2)" "unprognostic (2.07e-1)" "unprognostic (9.67e-2)" "unprognostic (2.17e-2)" "unprognostic (2.00e-1)" "unprognostic (3.87e-2)" "unprognostic (4.43e-1)" PTP4A3 "PRL-3, PRL-R, PRL3" ENSG00000184489 "Protein tyrosine phosphatase 4A3" O75365 8 141391995-141432454 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 516.5;skeletal muscle: 565.4" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 6.7;Brain inhibitory neurons: 11.1;Cardiomyocytes: 12.6;Choroid plexus epithelial cells: 9.3;Megakaryocytes: 6.2;Oligodendrocyte progenitor cells: 5.0;Other brain neurons: 14.8;Papillary tip epithelial cells: 4.9;Podocytes: 11.1;Renal collecting duct intercalated cells: 19.1;Renal connecting tubule cells: 6.9;Vascular smooth muscle cells: 18.8" "Cell type enhanced" "Detected in many" "vascular associated smooth muscle cell: 107.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 55.4;non-classical monocyte: 54.4" "Group enriched" "Detected in all" 6 "granulocytes: 55.4;monocytes: 54.4" "Cancer enhanced" "Detected in many" "Myeloma: 27.3" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Cardiomyocytes, Minor Salivary Gland - Endothelial cells, Pituitary gland - Corticotropes, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003281 Uncertain NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 74: Non-specific - Signal transduction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 102: Non-specific - Mixed function" 10 "HPA003281: " "unprognostic (1.28e-1)" "unprognostic (3.67e-1)" "unprognostic (4.63e-1)" "unprognostic (3.39e-2)" "unprognostic (8.01e-2)" "unprognostic (4.04e-1)" "unprognostic (2.38e-1)" "unprognostic (1.19e-1)" "unprognostic (3.47e-2)" "unprognostic (7.50e-2)" "potential prognostic unfavorable (5.36e-5)" "unprognostic (1.67e-1)" "unprognostic (4.75e-2)" "unprognostic (4.11e-3)" "unprognostic (2.15e-1)" "unprognostic (1.61e-2)" "unprognostic (1.46e-1)" "unprognostic (2.61e-2)" "unprognostic (2.69e-1)" "unprognostic (1.41e-1)" "unprognostic (3.41e-1)" "unprognostic (1.56e-2)" "unprognostic (1.66e-1)" "unprognostic (1.58e-2)" "unprognostic (1.65e-1)" "unprognostic (1.12e-1)" "unprognostic (7.19e-2)" "unprognostic (9.16e-2)" "unprognostic (1.16e-1)" "unprognostic (2.13e-2)" "unprognostic (2.65e-1)" PTPA "PPP2R4, PR53" ENSG00000119383 "Protein phosphatase 2 phosphatase activator" Q15257 9 129110950-129148946 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Disease variant, Intellectual disability, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 26.8;Loop of henle epithelial cells: 28.7;Papillary tip epithelial cells: 25.7;Podocytes: 21.9;Proximal tubule cells: 24.2;Renal collecting duct intercalated cells: 24.4;Renal collecting duct principal cells: 25.6;Renal connecting tubule cells: 23.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005695, CAB022068, CAB035999, CAB080052, CAB080054, CAB080098" Approved Enhanced Nucleoplasm,Cytosol NA NA 2300000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 38: Sub-cortical - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 20 Nucleoplasm Cytosol "CAB022068: , CAB035999: , CAB080052: , CAB080054: , CAB080098: , HPA005695: " "unprognostic (2.51e-1)" "unprognostic (8.89e-2)" "unprognostic (1.81e-1)" "unprognostic (1.17e-2)" "unprognostic (2.70e-3)" "unprognostic (5.06e-2)" "unprognostic (3.44e-2)" "unprognostic (5.93e-2)" "unprognostic (2.12e-1)" "unprognostic (1.90e-2)" "unprognostic (5.46e-1)" "potential prognostic favorable (9.12e-5)" "unprognostic (6.79e-2)" "unprognostic (2.87e-2)" "unprognostic (3.19e-2)" "unprognostic (3.51e-2)" "unprognostic (6.70e-2)" "unprognostic (4.08e-2)" "unprognostic (6.39e-2)" "unprognostic (1.52e-1)" "unprognostic (1.85e-1)" "unprognostic (2.94e-1)" "unprognostic (9.95e-3)" "unprognostic (5.53e-2)" "unprognostic (1.19e-1)" "unprognostic (1.59e-1)" "unprognostic (1.33e-1)" "unprognostic (6.97e-2)" "unprognostic (1.04e-3)" PTPDC1 "FLJ37312, PTP9Q22" ENSG00000158079 "Protein tyrosine phosphatase domain containing 1" A2A3K4 9 94030794-94109856 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 7 "Pituicytes/FSCs: 796.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016747, HPA026832" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 21 Nucleoplasm Cytosol "HPA016747: , HPA026832: " "unprognostic (5.39e-2)" "unprognostic (6.31e-3)" "unprognostic (3.34e-1)" "unprognostic (2.74e-1)" "unprognostic (1.14e-2)" "unprognostic (1.89e-2)" "unprognostic (1.56e-1)" "unprognostic (1.79e-1)" "unprognostic (9.76e-3)" "potential prognostic unfavorable (9.33e-4)" "unprognostic (2.12e-3)" "unprognostic (2.52e-3)" "unprognostic (2.08e-2)" "unprognostic (7.72e-3)" "unprognostic (1.05e-1)" "unprognostic (9.21e-2)" "unprognostic (1.62e-1)" "unprognostic (2.90e-1)" "unprognostic (1.10e-1)" "unprognostic (3.45e-1)" "unprognostic (4.98e-3)" "unprognostic (2.78e-2)" "unprognostic (8.06e-2)" "unprognostic (2.16e-3)" "unprognostic (1.11e-3)" "unprognostic (3.92e-1)" "unprognostic (3.03e-2)" "unprognostic (2.43e-1)" "unprognostic (5.97e-2)" "unprognostic (3.30e-1)" PTPMT1 "DUSP23, MOSP, PLIP" ENSG00000110536 "Protein tyrosine phosphatase mitochondrial 1" Q8WUK0 11 47565430-47573461 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 170.9;Late primary spermatocytes: 269.0;Late spermatids: 849.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043932, HPA060060" Approved Enhanced Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 24: Non-specific - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 31 Mitochondria "HPA043932: , HPA060060: " "unprognostic (2.49e-2)" "unprognostic (1.13e-2)" "unprognostic (3.34e-2)" "unprognostic (2.84e-1)" "unprognostic (2.17e-1)" "unprognostic (1.10e-1)" "unprognostic (2.75e-2)" "unprognostic (1.27e-1)" "unprognostic (2.93e-2)" "unprognostic (2.61e-2)" "unprognostic (2.61e-2)" "unprognostic (3.23e-2)" "unprognostic (4.40e-1)" "validated prognostic unfavorable (2.42e-4)" "validated prognostic unfavorable (4.91e-4)" "unprognostic (2.21e-1)" "unprognostic (2.30e-2)" "unprognostic (1.89e-1)" "unprognostic (9.28e-2)" "unprognostic (1.02e-1)" "unprognostic (1.41e-1)" "unprognostic (1.03e-1)" "unprognostic (2.08e-1)" "unprognostic (9.66e-3)" "unprognostic (1.55e-1)" "unprognostic (6.67e-2)" "unprognostic (1.29e-2)" "unprognostic (1.23e-1)" "unprognostic (1.11e-1)" "unprognostic (2.37e-2)" "unprognostic (3.41e-1)" PTPN1 PTP1B ENSG00000196396 "Protein tyrosine phosphatase non-receptor type 1" P18031 20 50510321-50585241 "Enzymes, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 687.8;Alveolar cells type 2: 690.1;cDC: 452.3;monocytes: 473.1;Plasma cells: 605.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009329, HPA012542, CAB015217" Approved Supported "Endoplasmic reticulum,Cytosol" NA NA 3500 "Cluster 32: Basophils - Transcription" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 82: Dendritic cells - Antigen presentation" 136 "Endoplasmic reticulum" Cytosol "CAB009329: , CAB015217: , HPA012542: " "unprognostic (3.19e-1)" "unprognostic (1.02e-1)" "unprognostic (3.40e-1)" "unprognostic (1.93e-1)" "unprognostic (1.40e-1)" "unprognostic (1.06e-1)" "unprognostic (8.89e-2)" "unprognostic (4.86e-2)" "unprognostic (1.31e-1)" "unprognostic (2.11e-2)" "unprognostic (1.66e-2)" "unprognostic (7.93e-2)" "unprognostic (5.35e-2)" "unprognostic (1.14e-3)" "unprognostic (3.81e-2)" "unprognostic (2.62e-1)" "unprognostic (1.72e-1)" "unprognostic (1.10e-2)" "unprognostic (1.56e-1)" "unprognostic (5.84e-3)" "unprognostic (3.51e-3)" "unprognostic (3.08e-2)" "potential prognostic unfavorable (3.67e-4)" "unprognostic (1.02e-1)" "unprognostic (6.27e-2)" "unprognostic (2.78e-3)" "unprognostic (1.80e-1)" "unprognostic (8.07e-2)" "unprognostic (4.21e-2)" "unprognostic (1.34e-2)" "unprognostic (1.81e-1)" PTPN11 "BPTP3, NS1, PTP2C, SH-PTP2, SHP-2, SHP2" ENSG00000179295 "Protein tyrosine phosphatase non-receptor type 11" Q06124 12 112418351-112509918 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Hydrolase, Protein phosphatase" "Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005377 Approved Supported "Nucleoplasm,Nucleoli rim,Actin filaments,Cytosol" NA NA 100000 "Cluster 14: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 131 "Nucleoli rim" "Nucleoplasm, Actin filaments, Cytosol" "CAB005377: " "unprognostic (1.43e-1)" "unprognostic (6.88e-3)" "unprognostic (2.42e-1)" "unprognostic (1.08e-2)" "unprognostic (3.63e-1)" "unprognostic (9.85e-2)" "unprognostic (6.21e-2)" "unprognostic (7.02e-2)" "unprognostic (1.06e-1)" "unprognostic (3.57e-2)" "potential prognostic favorable (8.07e-4)" "unprognostic (4.22e-2)" "unprognostic (1.55e-1)" "unprognostic (2.85e-2)" "unprognostic (5.69e-2)" "unprognostic (2.00e-2)" "unprognostic (3.78e-3)" "unprognostic (5.37e-2)" "unprognostic (1.76e-1)" "unprognostic (5.19e-2)" "potential prognostic unfavorable (1.84e-4)" "unprognostic (3.55e-2)" "unprognostic (3.66e-2)" "unprognostic (1.31e-2)" "unprognostic (4.10e-2)" "unprognostic (8.12e-3)" "unprognostic (1.43e-1)" "unprognostic (1.39e-1)" "unprognostic (8.63e-2)" "unprognostic (3.56e-2)" "unprognostic (1.39e-1)" PTPN12 "PTP-PEST, PTPG1" ENSG00000127947 "Protein tyrosine phosphatase non-receptor type 12" Q05209 7 77537295-77640069 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 661.6;Neutrophils: 2006.8;Platelets: 922.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Kidney - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007038, HPA007097" Approved Approved "Plasma membrane,Cytosol" NA NA 370000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 25: Non-specific - Transcription" "Cluster 72: Neuronal - Signal transduction" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 35 "Plasma membrane" Cytosol "HPA007038: , HPA007097: " "unprognostic (7.60e-2)" "unprognostic (1.28e-1)" "unprognostic (1.49e-1)" "potential prognostic unfavorable (3.32e-6)" "unprognostic (2.28e-1)" "unprognostic (4.75e-3)" "unprognostic (1.47e-1)" "unprognostic (1.80e-3)" "unprognostic (1.56e-2)" "unprognostic (1.53e-2)" "potential prognostic favorable (4.67e-4)" "unprognostic (7.93e-3)" "unprognostic (1.16e-1)" "unprognostic (2.73e-3)" "unprognostic (2.04e-2)" "unprognostic (7.74e-3)" "unprognostic (4.05e-2)" "unprognostic (5.58e-2)" "unprognostic (1.41e-1)" "unprognostic (1.31e-1)" "unprognostic (3.83e-2)" "unprognostic (4.32e-3)" "unprognostic (8.53e-3)" "unprognostic (2.37e-1)" "unprognostic (1.29e-1)" "unprognostic (1.57e-1)" "unprognostic (6.74e-2)" "unprognostic (4.48e-2)" "unprognostic (5.81e-1)" "unprognostic (1.70e-1)" "unprognostic (1.10e-1)" PTPN13 "PTP-BAS, PTP-BL, PTP1E, PTPL1" ENSG00000163629 "Protein tyrosine phosphatase non-receptor type 13" Q12923 4 86594315-86815171 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 115.1" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 877.7;Ocular epithelial cells: 1473.7;Podocytes: 1754.6;Renal connecting tubule cells: 786.2;Retinal pigment epithelial cells: 1381.2;Rod photoreceptor cells: 1490.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Liver - Hepatic stellate cells, Lung - Alveolar cells type 2, Skin - Keratinocyte (other), Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002213, HPA065290" Approved Approved "Plasma membrane,Primary cilium,Primary cilium transition zone,Basal body,Cytosol" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 42: Retina - Visual perception" "Cluster 55: Non-specific - Transcription" "Cluster 1: Neuronal - Visual perception" "Cluster 100: Stratified epithelial cells - Barrier functions" 33 "Plasma membrane, Primary cilium" "Primary cilium transition zone, Basal body, Cytosol" "CAB002213: , HPA065290: " "unprognostic (6.40e-3)" "unprognostic (2.37e-2)" "unprognostic (1.40e-1)" "unprognostic (9.20e-2)" "unprognostic (2.39e-1)" "unprognostic (1.64e-2)" "unprognostic (1.85e-1)" "unprognostic (5.34e-1)" "unprognostic (7.81e-3)" "unprognostic (9.60e-2)" "validated prognostic favorable (2.43e-6)" "validated prognostic favorable (4.91e-4)" "unprognostic (2.46e-1)" "unprognostic (1.28e-1)" "unprognostic (7.18e-2)" "unprognostic (2.12e-1)" "unprognostic (2.61e-1)" "unprognostic (1.33e-1)" "unprognostic (2.62e-2)" "unprognostic (2.96e-1)" "unprognostic (2.12e-2)" "unprognostic (1.10e-1)" "unprognostic (1.27e-1)" "unprognostic (1.40e-1)" "unprognostic (3.19e-1)" "unprognostic (3.55e-1)" "unprognostic (2.28e-3)" "unprognostic (1.62e-1)" "unprognostic (2.00e-1)" "unprognostic (6.05e-2)" PTPN14 "PEZ, PTPD2" ENSG00000152104 "Protein tyrosine phosphatase non-receptor type 14" Q15678 1 214348700-214552449 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 401.1;Endometrial glandular cells: 434.4;Endometrial luminal cells: 351.2;Loop of henle epithelial cells: 565.3;Myonuclei: 512.1;Podocytes: 666.4" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 211.6;endothelial cell: 396.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Spleen - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB011469, HPA053864, CAB069441" Uncertain Supported Nucleoplasm NA NA "Cluster 58: Skin - Keratinization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 51: Secretory epithelial cells - Mixed function" 41 Nucleoplasm "CAB011469: , CAB069441: , HPA053864: " "unprognostic (4.16e-1)" "unprognostic (8.75e-2)" "unprognostic (9.80e-2)" "unprognostic (2.96e-2)" "unprognostic (5.81e-2)" "potential prognostic unfavorable (5.78e-6)" "unprognostic (1.19e-1)" "unprognostic (1.76e-3)" "unprognostic (2.28e-1)" "unprognostic (7.29e-2)" "potential prognostic favorable (1.63e-6)" "unprognostic (2.00e-3)" "unprognostic (1.94e-1)" "unprognostic (8.02e-2)" "unprognostic (3.58e-1)" "unprognostic (1.73e-2)" "unprognostic (4.38e-3)" "unprognostic (1.22e-1)" "unprognostic (1.11e-1)" "unprognostic (2.64e-2)" "unprognostic (1.11e-2)" "potential prognostic unfavorable (9.17e-4)" "unprognostic (6.57e-2)" "unprognostic (2.55e-1)" "unprognostic (1.15e-2)" "unprognostic (6.96e-2)" "unprognostic (2.19e-1)" "unprognostic (2.05e-2)" "unprognostic (1.40e-1)" "unprognostic (7.41e-2)" "unprognostic (1.53e-1)" PTPN18 BDP1 ENSG00000072135 "Protein tyrosine phosphatase non-receptor type 18" Q99952 2 130356045-130375405 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Platelets: 1048.0;Tuft cells: 657.1" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 120.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB012174, HPA053367" Uncertain Approved "Intermediate filaments" NA NA 380000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 5: Spleen - Immune response" "Cluster 25: Non-specific - Transcription" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 47: Platelets - Hemostasis" 11 "Intermediate filaments" "CAB012174: , HPA053367: " "unprognostic (2.82e-2)" "unprognostic (7.80e-2)" "unprognostic (1.97e-2)" "unprognostic (6.97e-2)" "unprognostic (8.83e-3)" "unprognostic (3.90e-3)" "unprognostic (3.59e-3)" "unprognostic (2.04e-1)" "unprognostic (4.97e-3)" "unprognostic (1.78e-2)" "unprognostic (2.48e-3)" "unprognostic (2.55e-1)" "potential prognostic favorable (1.71e-4)" "unprognostic (8.46e-2)" "unprognostic (1.26e-2)" "unprognostic (1.20e-1)" "unprognostic (8.07e-2)" "unprognostic (1.42e-1)" "unprognostic (6.28e-2)" "unprognostic (7.92e-2)" "unprognostic (1.32e-1)" "unprognostic (1.38e-1)" "unprognostic (1.01e-1)" "unprognostic (3.09e-1)" "unprognostic (2.49e-2)" "unprognostic (5.79e-3)" "unprognostic (3.49e-1)" "unprognostic (1.93e-3)" "unprognostic (3.30e-1)" "unprognostic (1.27e-1)" "unprognostic (2.50e-1)" PTPN2 "PTPT, TC-PTP, TCELLPTP, TCPTP" ENSG00000175354 "Protein tyrosine phosphatase non-receptor type 2" P17706 18 12785478-12929643 "Enzymes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 92.9" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Neutrophils, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015004, HPA046176" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 44: Plasma cells - Antibody production & secretion" 41 Nucleoplasm Cytosol "HPA015004: , HPA046176: " "unprognostic (2.87e-2)" "unprognostic (2.19e-2)" "unprognostic (2.35e-3)" "unprognostic (5.56e-2)" "unprognostic (1.66e-1)" "unprognostic (1.85e-1)" "unprognostic (7.35e-3)" "unprognostic (6.15e-2)" "unprognostic (9.58e-2)" "unprognostic (2.37e-2)" "potential prognostic unfavorable (3.38e-4)" "unprognostic (1.01e-1)" "unprognostic (1.35e-1)" "unprognostic (7.36e-2)" "unprognostic (8.26e-3)" "unprognostic (1.53e-2)" "unprognostic (1.63e-1)" "unprognostic (7.15e-3)" "unprognostic (1.23e-1)" "potential prognostic favorable (1.15e-4)" "unprognostic (2.23e-1)" "unprognostic (1.61e-3)" "potential prognostic unfavorable (8.17e-4)" "unprognostic (6.72e-2)" "unprognostic (1.36e-1)" "unprognostic (2.64e-1)" "unprognostic (4.06e-2)" "unprognostic (1.16e-1)" "unprognostic (4.17e-1)" "unprognostic (6.00e-2)" "unprognostic (1.36e-1)" PTPN20 "bA142I17.1, bA42B19.1, CT126, DKFZP566K0524, PTPN20A, PTPN20B" ENSG00000204179 "Protein tyrosine phosphatase non-receptor type 20" Q4JDL3 10 46911396-47002488 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 12.7;tongue: 13.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 48.9;Distal convoluted tubule cells: 61.9;Early spermatids: 71.8;Gonadotrophs: 54.6;Proximal tubule cells: 83.3;Renal collecting duct intercalated cells: 48.0;Renal collecting duct principal cells: 37.6;Renal connecting tubule cells: 51.7" "Cell type enhanced" "Detected in all" "lower rhombic lip: 131.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Not detected" "Not detected" "Region enhanced" "Detected in single" "midbrain: 1.6" "HPA043337, HPA046896, HPA048310, HPA069148" Enhanced Supported "Centriolar satellite" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 109: Neurons - Neuronal signaling" 1 "Centriolar satellite" "HPA043337: , HPA046896: , HPA048310: , HPA069148: " "unprognostic (2.19e-1)" "unprognostic (8.07e-2)" "unprognostic (2.49e-1)" "unprognostic (2.31e-2)" "unprognostic (1.69e-1)" "unprognostic (3.18e-2)" "unprognostic (2.60e-2)" "unprognostic (1.35e-1)" "unprognostic (1.41e-1)" "unprognostic (1.48e-1)" "unprognostic (2.17e-3)" "unprognostic (9.28e-2)" "unprognostic (1.56e-1)" "unprognostic (1.43e-1)" "unprognostic (1.54e-1)" "unprognostic (2.91e-2)" "unprognostic (1.76e-1)" "unprognostic (7.76e-2)" "unprognostic (3.41e-1)" "unprognostic (8.96e-2)" "unprognostic (4.18e-2)" PTPN21 "PTPD1, PTPRL10" ENSG00000070778 "Protein tyrosine phosphatase non-receptor type 21" Q16825 14 88465778-88555007 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 142.0;Podocytes: 166.5;Renal collecting duct intercalated cells: 156.8;Syncytiotrophoblasts: 192.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 1, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011468, HPA073999" Approved Approved "Golgi apparatus,Cytosol" NA NA "Cluster 47: Testis - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 39 Cytosol "Golgi apparatus" "CAB011468: , HPA073999: " "unprognostic (4.26e-1)" "unprognostic (3.16e-1)" "unprognostic (2.17e-1)" "unprognostic (8.15e-3)" "unprognostic (2.47e-1)" "unprognostic (2.01e-1)" "unprognostic (1.26e-1)" "unprognostic (1.40e-1)" "unprognostic (1.38e-1)" "unprognostic (1.37e-1)" "potential prognostic favorable (1.11e-6)" "unprognostic (3.41e-3)" "unprognostic (1.05e-3)" "unprognostic (5.85e-2)" "unprognostic (5.04e-2)" "unprognostic (5.63e-2)" "unprognostic (6.61e-2)" "unprognostic (1.45e-3)" "unprognostic (4.60e-2)" "unprognostic (1.99e-1)" "unprognostic (5.25e-2)" "unprognostic (1.44e-1)" "unprognostic (1.35e-1)" "unprognostic (9.99e-3)" "unprognostic (1.44e-2)" "unprognostic (3.62e-2)" "unprognostic (6.34e-2)" "unprognostic (5.65e-2)" "unprognostic (2.06e-1)" "unprognostic (1.02e-1)" "unprognostic (4.62e-2)" PTPN22 "Lyp, Lyp1, Lyp2, PTPN8" ENSG00000134242 "Protein tyrosine phosphatase non-receptor type 22" Q9Y2R2 1 113813811-113871753 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Autophagy, Immunity, Lipid metabolism" "Hydrolase, Protein phosphatase" "Diabetes mellitus, Disease variant, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 35.9;lymphoid tissue: 19.0" "Cell type enhanced" "Detected in many" "B-cells: 128.7;Innate lymphoid cells: 465.3;Mast cells: 119.6;Neutrophil progenitors: 554.8;Neutrophils: 193.8;NK-cells: 505.8;T-cells: 561.3;Thymocytes: 247.3" "Cell type enriched" "Detected in many" 41 "leukocyte: 298.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 8 "Leukemia: 15.6;lymphoma: 23.2;Myeloma: 12.8" "Adipose visceral - T-cells, Breast - T-cells, Kidney - T-cells, Liver - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Thyroid gland - T-cells" "Region enriched" "Detected in single" 11 "cerebellum: 5.3" "Not detected" "Not detected" "HPA004912, CAB012209, HPA013350" Approved Uncertain "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 12: Non-specific - Vasculature" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 16 Nucleoplasm "Vesicles, Plasma membrane" "CAB012209: , HPA004912: , HPA013350: " "unprognostic (1.18e-2)" "unprognostic (9.30e-3)" "unprognostic (7.64e-2)" "unprognostic (1.62e-1)" "unprognostic (6.12e-2)" "unprognostic (2.60e-1)" "unprognostic (3.76e-2)" "unprognostic (5.28e-3)" "unprognostic (4.31e-2)" "unprognostic (2.56e-1)" "unprognostic (1.59e-2)" "unprognostic (2.33e-2)" "unprognostic (3.55e-2)" "unprognostic (3.74e-1)" "unprognostic (3.16e-1)" "unprognostic (4.23e-1)" "unprognostic (7.81e-2)" "unprognostic (1.71e-1)" "unprognostic (5.54e-2)" "unprognostic (5.15e-2)" "unprognostic (4.62e-2)" "unprognostic (2.85e-1)" "unprognostic (2.41e-1)" "unprognostic (3.03e-1)" PTPN23 "DKFZP564F0923, HD-PTP, KIAA1471" ENSG00000076201 "Protein tyrosine phosphatase non-receptor type 23" Q9H3S7 3 47381011-47413435 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Transport" "Hydrolase, Protein phosphatase" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016845 Approved Supported "Nucleoplasm,Nuclear bodies,Vesicles,Centriolar satellite,Basal body,Cytosol,Calyx,Mid piece" Yes No "Cluster 32: Basophils - Transcription" "Cluster 24: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 17: Non-specific - RNA processing" 44 "Nucleoplasm, Nuclear bodies, Basal body" "Vesicles, Centriolar satellite, Cytosol, Calyx, Mid piece" "HPA016845: " "unprognostic (4.22e-2)" "unprognostic (7.52e-2)" "unprognostic (2.36e-1)" "unprognostic (1.05e-1)" "unprognostic (3.10e-1)" "unprognostic (9.72e-2)" "unprognostic (1.21e-1)" "unprognostic (5.26e-2)" "unprognostic (2.61e-3)" "unprognostic (1.80e-2)" "potential prognostic favorable (9.75e-5)" "unprognostic (8.96e-2)" "unprognostic (3.36e-2)" "unprognostic (1.38e-1)" "unprognostic (1.99e-3)" "unprognostic (5.18e-2)" "unprognostic (2.69e-2)" "unprognostic (2.99e-2)" "unprognostic (5.10e-2)" "unprognostic (1.44e-1)" "unprognostic (3.33e-1)" "unprognostic (2.25e-1)" "unprognostic (3.53e-2)" "unprognostic (1.91e-1)" "unprognostic (2.54e-2)" "unprognostic (2.08e-2)" "unprognostic (6.22e-3)" "unprognostic (7.31e-2)" "unprognostic (3.39e-1)" "unprognostic (3.94e-2)" "unprognostic (3.61e-2)" PTPN3 PTPH1 ENSG00000070159 "Protein tyrosine phosphatase non-receptor type 3" P26045 9 109375466-109498313 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 59.5;tongue: 43.8" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 302.9;Esophageal apical cells: 236.9;Loop of henle epithelial cells: 227.2;Myonuclei: 344.1;Renal connecting tubule cells: 267.1" "Cell type enhanced" "Detected in all" "ependymal cell: 192.8;thalamic excitatory: 239.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038343, HPA046728" Approved NA NA "Cluster 76: Non-specific - Metabolism" "Cluster 38: Sub-cortical - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 51: Secretory epithelial cells - Mixed function" 61 "HPA038343: , HPA046728: " "unprognostic (1.56e-1)" "unprognostic (1.40e-3)" "unprognostic (1.37e-1)" "unprognostic (9.68e-2)" "unprognostic (1.40e-1)" "unprognostic (5.34e-2)" "unprognostic (3.70e-2)" "unprognostic (2.69e-1)" "unprognostic (8.49e-2)" "validated prognostic favorable (3.42e-10)" "validated prognostic favorable (5.56e-4)" "unprognostic (1.19e-1)" "unprognostic (2.86e-1)" "unprognostic (2.16e-1)" "unprognostic (1.53e-1)" "unprognostic (1.54e-1)" "unprognostic (5.93e-2)" "unprognostic (1.60e-1)" "unprognostic (1.07e-1)" "unprognostic (1.48e-1)" "unprognostic (1.10e-1)" "unprognostic (5.22e-2)" "unprognostic (1.57e-1)" "unprognostic (7.40e-3)" "unprognostic (7.36e-2)" "unprognostic (2.38e-1)" "unprognostic (4.63e-2)" "unprognostic (1.75e-1)" "unprognostic (2.10e-1)" "unprognostic (8.85e-2)" PTPN4 PTPMEG ENSG00000088179 "Protein tyrosine phosphatase non-receptor type 4" P29074 2 119759922-119984899 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Retinal horizontal cells: 659.1;Sertoli cells: 463.6;Somatotrophs: 491.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 35.1;MAIT T-cell: 28.2;memory CD4 T-cell: 16.9;memory CD8 T-cell: 27.9;naive CD8 T-cell: 19.2;NK-cell: 24.5;T-reg: 11.0" "Group enriched" "Detected in many" 16 "NK-cells: 24.5;T-cells: 35.1" "Low cancer specificity" "Detected in all" "Stomach - Parietal cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019351 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 15: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 20 Nucleoplasm "Plasma membrane, Cytosol" "HPA019351: " "unprognostic (1.78e-1)" "unprognostic (1.23e-1)" "unprognostic (7.19e-2)" "unprognostic (7.53e-2)" "unprognostic (1.76e-1)" "unprognostic (1.46e-1)" "unprognostic (1.86e-1)" "unprognostic (7.28e-3)" "unprognostic (1.84e-2)" "unprognostic (1.09e-1)" "potential prognostic favorable (9.38e-4)" "unprognostic (9.61e-3)" "unprognostic (4.45e-1)" "unprognostic (3.25e-2)" "unprognostic (6.06e-2)" "unprognostic (4.25e-2)" "unprognostic (2.64e-3)" "unprognostic (1.28e-1)" "unprognostic (1.72e-2)" "unprognostic (3.36e-2)" "unprognostic (2.13e-1)" "unprognostic (1.21e-3)" "unprognostic (7.91e-3)" "unprognostic (4.26e-2)" "unprognostic (5.26e-2)" "unprognostic (3.17e-1)" "unprognostic (1.58e-2)" "unprognostic (6.51e-2)" "unprognostic (2.58e-2)" "unprognostic (4.45e-2)" "unprognostic (1.45e-1)" PTPN5 "PTPSTEP, STEP, STEP61" ENSG00000110786 "Protein tyrosine phosphatase non-receptor type 5" P54829 11 18727928-18792721 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 25 "brain: 301.3" "Group enriched" "Detected in some" 5 "Brain excitatory neurons: 48.0;Brain inhibitory neurons: 163.6;Other brain neurons: 64.6" "Cell type enhanced" "Detected in all" "medium spiny neuron: 328.5" "Group enriched" "Detected in some" 7 "Glioblastoma Multiforme (TCGA): 5.0;Testicular Germ Cell Tumor (TCGA): 6.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bone cancer: 2.6;Rhabdoid: 9.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031014, HPA072091" Supported Approved "Endoplasmic reticulum" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 35: Neurons - Synaptic function & neurogenesis" 23 "Endoplasmic reticulum" "HPA031014: , HPA072091: " "unprognostic (1.17e-1)" "unprognostic (7.50e-2)" "unprognostic (6.53e-2)" "potential prognostic favorable (8.52e-4)" "unprognostic (1.40e-2)" PTPN6 "HCP, HCPH, PTP-1C, SHP-1, SHP1" ENSG00000111679 "Protein tyrosine phosphatase non-receptor type 6" P29350 12 6946468-6961316 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 124.6;lymphoid tissue: 143.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 268.1;Megakaryocytes: 166.9;monocytes: 172.8;Neutrophil progenitors: 209.5;Neutrophils: 360.9;Tuft cells: 403.5" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 27.4;leukocyte: 65.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Leukemia: 169.7;lymphoma: 129.4;Myeloma: 80.7" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Skeletal muscle - Macrophages, Skin - Langerhans cells, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001466, CAB004572, CAB072845" Enhanced Supported Nucleoplasm,Nucleoli NA NA 5500000 "Cluster 29: Non-specific - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 96 Nucleoplasm Nucleoli "CAB004572: , CAB072845: , HPA001466: " "unprognostic (2.52e-2)" "unprognostic (7.23e-2)" "unprognostic (2.19e-2)" "unprognostic (8.61e-2)" "unprognostic (3.47e-2)" "unprognostic (2.10e-1)" "unprognostic (2.03e-2)" "unprognostic (3.09e-1)" "unprognostic (2.17e-1)" "unprognostic (2.19e-1)" "unprognostic (1.85e-2)" "unprognostic (2.99e-1)" "unprognostic (1.48e-1)" "unprognostic (1.08e-1)" "unprognostic (3.43e-1)" "unprognostic (7.78e-3)" "unprognostic (1.59e-1)" "unprognostic (1.26e-1)" "unprognostic (2.12e-1)" "unprognostic (3.36e-3)" "unprognostic (5.38e-2)" "unprognostic (9.42e-3)" "unprognostic (4.35e-3)" "unprognostic (2.82e-1)" "unprognostic (2.94e-2)" "unprognostic (3.81e-1)" "unprognostic (1.06e-2)" "unprognostic (1.26e-2)" "unprognostic (3.03e-3)" "unprognostic (4.43e-1)" "unprognostic (1.77e-1)" PTPN7 "HEPTP, LC-PTP" ENSG00000143851 "Protein tyrosine phosphatase non-receptor type 7" P35236 1 202147013-202161588 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 64.9;lymphoid tissue: 71.0" "Cell type enhanced" "Detected in many" "B-cells: 44.0;Erythrocyte progenitors: 47.2;Hematopoietic stem cells: 54.8;Innate lymphoid cells: 97.3;Mast cells: 108.9;Megakaryocyte progenitors: 64.7;Megakaryocyte-Erythroid progenitors: 53.0;Monocyte progenitors: 43.1;Neutrophil progenitors: 118.2;Neutrophils: 60.3;NK-cells: 127.0;Podocytes: 51.1;Sertoli cells: 79.4;T-cells: 121.9;Thymocytes: 45.7" "Cell type enhanced" "Detected in many" "leukocyte: 105.7;medium spiny neuron: 55.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "granulocytes: 35.6;NK-cells: 39.9;T-cells: 46.5" "Group enriched" "Detected in some" 32 "Leukemia: 132.2;lymphoma: 66.1;Myeloma: 52.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Heart muscle - T-cells, Liver - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Spleen - T-cells, Testis - Sertoli cells, Thyroid gland - T-cells" "Region enriched" "Detected in single" 9 "basal ganglia: 6.1" "Region enriched" "Detected in single" 17 "basal ganglia: 16.5" "CAB009530, HPA019118" Approved Supported "Microtubules,Mitotic spindle,Cytosol" Yes NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 33: Neurons - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 9 Cytosol "Microtubules, Mitotic spindle" "CAB009530: , HPA019118: " "unprognostic (5.55e-2)" "unprognostic (3.04e-3)" "unprognostic (9.08e-3)" "unprognostic (2.27e-3)" "unprognostic (1.46e-1)" "unprognostic (5.49e-2)" "unprognostic (3.16e-2)" "unprognostic (1.65e-1)" "potential prognostic favorable (1.03e-4)" "unprognostic (1.19e-3)" "unprognostic (6.32e-2)" "unprognostic (2.45e-2)" "unprognostic (3.96e-2)" "unprognostic (1.63e-2)" "unprognostic (8.07e-2)" "unprognostic (1.52e-1)" "unprognostic (3.03e-1)" "unprognostic (7.13e-2)" "unprognostic (2.64e-2)" "unprognostic (2.64e-2)" "unprognostic (2.25e-2)" "unprognostic (3.00e-2)" "unprognostic (7.76e-3)" "unprognostic (2.05e-1)" "unprognostic (2.28e-1)" "unprognostic (4.02e-1)" PTPN9 MEG2 ENSG00000169410 "Protein tyrosine phosphatase non-receptor type 9" P43378 15 75463251-75579315 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Loop of henle epithelial cells: 105.1;Podocytes: 211.9;Proximal tubule cells: 123.3;Renal collecting duct intercalated cells: 128.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Adrenal gland - Fibroblasts, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041922 Approved Approved Vesicles NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 58: Non-specific - Nuclear processes" "Cluster 105: Non-specific - Mixed function" 43 Vesicles "HPA041922: " "unprognostic (5.34e-3)" "unprognostic (2.50e-1)" "unprognostic (3.29e-2)" "unprognostic (1.30e-2)" "unprognostic (1.89e-1)" "potential prognostic unfavorable (2.49e-4)" "unprognostic (2.93e-2)" "unprognostic (1.29e-2)" "unprognostic (1.78e-2)" "unprognostic (4.00e-2)" "validated prognostic favorable (2.29e-7)" "validated prognostic favorable (1.84e-5)" "unprognostic (1.61e-2)" "unprognostic (6.78e-2)" "unprognostic (1.17e-2)" "unprognostic (2.38e-2)" "unprognostic (2.95e-2)" "unprognostic (1.75e-1)" "unprognostic (3.60e-1)" "unprognostic (2.95e-1)" "unprognostic (2.45e-1)" "unprognostic (6.55e-3)" "unprognostic (7.24e-2)" "unprognostic (1.66e-1)" "unprognostic (4.38e-2)" "unprognostic (2.14e-1)" "unprognostic (9.51e-2)" "unprognostic (7.85e-2)" "unprognostic (2.53e-1)" "unprognostic (1.85e-1)" "unprognostic (8.41e-2)" PTPRA "HLPR, HPTPA, LRP, PTPA, PTPRL2, RPTPA" ENSG00000132670 "Protein tyrosine phosphatase receptor type A" P18433 20 2873420-3039076 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Spleen - Endothelial cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029412, CAB034366, HPA069480" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 73: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 26 Vesicles Nucleoplasm "CAB034366: , HPA029412: , HPA069480: " "unprognostic (3.00e-2)" "unprognostic (1.95e-1)" "unprognostic (1.95e-1)" "unprognostic (3.11e-2)" "unprognostic (1.21e-1)" "unprognostic (2.67e-2)" "unprognostic (9.68e-2)" "unprognostic (3.02e-2)" "unprognostic (6.42e-2)" "unprognostic (4.75e-2)" "potential prognostic favorable (1.23e-5)" "unprognostic (5.65e-3)" "unprognostic (3.20e-2)" "unprognostic (1.35e-2)" "unprognostic (6.20e-2)" "unprognostic (1.20e-1)" "unprognostic (1.67e-1)" "unprognostic (1.49e-2)" "unprognostic (9.19e-3)" "unprognostic (1.37e-2)" "unprognostic (1.80e-1)" "unprognostic (3.36e-2)" "unprognostic (1.03e-1)" "unprognostic (1.55e-1)" "unprognostic (3.29e-1)" "unprognostic (1.27e-1)" "unprognostic (3.87e-1)" "unprognostic (8.98e-2)" "unprognostic (2.47e-1)" "unprognostic (3.10e-1)" "unprognostic (2.45e-1)" PTPRB PTPB ENSG00000127329 "Protein tyrosine phosphatase receptor type B" P23467 12 70515870-70637440 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Lymphatic endothelial cells: 281.5;Pituicytes/FSCs: 274.8;Vascular endothelial cells: 866.5" "Cell type enriched" "Detected in many" 5 "endothelial cell: 1515.8" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 26.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 10.7" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Minor Salivary Gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004782, HPA067868" Uncertain Approved "Vesicles,Plasma membrane,Cell Junctions" NA NA 4400000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 9 "Plasma membrane" "Vesicles, Cell Junctions" "CAB004782: , HPA067868: " "unprognostic (1.54e-1)" "unprognostic (1.03e-1)" "unprognostic (9.59e-2)" "potential prognostic unfavorable (1.92e-4)" "unprognostic (5.30e-2)" "unprognostic (4.75e-2)" "unprognostic (6.96e-2)" "unprognostic (1.07e-1)" "unprognostic (6.10e-2)" "unprognostic (2.04e-1)" "validated prognostic favorable (1.59e-14)" "validated prognostic favorable (3.59e-5)" "unprognostic (5.40e-2)" "validated prognostic favorable (7.22e-4)" "validated prognostic favorable (3.02e-4)" "unprognostic (8.90e-2)" "unprognostic (2.26e-1)" "unprognostic (5.39e-3)" "unprognostic (4.66e-2)" "unprognostic (1.84e-1)" "unprognostic (8.76e-2)" "unprognostic (2.38e-1)" "unprognostic (1.38e-1)" "unprognostic (2.06e-1)" "unprognostic (1.70e-1)" "unprognostic (8.94e-2)" "unprognostic (1.05e-2)" "unprognostic (4.40e-3)" "unprognostic (1.81e-1)" "unprognostic (2.47e-1)" "unprognostic (1.43e-1)" PTPRC "CD45, GP180, LCA, T200" ENSG00000081237 "Protein tyrosine phosphatase receptor type C" P08575 1 198638457-198757476 "Cancer-related genes, CD markers, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" "Hydrolase, Protein phosphatase" "Cancer-related genes, Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 273.8" "Cell type enriched" "Detected in many" 4 "Neutrophils: 4182.4" "Group enriched" "Detected in many" 14 "central nervous system macrophage: 1145.9;leukocyte: 3019.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Leukemia: 84.8;lymphoma: 127.0" "Adipose visceral - T-cells, Adrenal gland - Macrophages, Breast - T-cells, Kidney - T-cells, Lung - NK-cells (Lung), Prostate - T-cells, Skin - T-cells, Thyroid gland - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB000052, HPA000440, CAB002800, CAB056154, CAB068221, CAB080251" Enhanced Uncertain Nucleoplasm,Vesicles "Intracellular and membrane" Enzyme NA NA 6800000 "Cluster 28: Neutrophils - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 102: Non-specific - Mixed function" 15 "Nucleoplasm, Vesicles" "CAB000052: , CAB002800: , CAB056154: , CAB068221: , CAB080251: , HPA000440: " "unprognostic (3.82e-2)" "unprognostic (6.75e-2)" "unprognostic (3.07e-1)" "unprognostic (6.56e-2)" "unprognostic (1.13e-1)" "unprognostic (1.32e-1)" "unprognostic (2.78e-1)" "unprognostic (2.28e-1)" "unprognostic (2.30e-3)" "unprognostic (1.63e-1)" "unprognostic (1.44e-2)" "unprognostic (1.11e-1)" "unprognostic (5.98e-2)" "unprognostic (2.78e-1)" "unprognostic (2.11e-2)" "potential prognostic favorable (5.92e-5)" "unprognostic (1.53e-1)" "unprognostic (1.92e-1)" "unprognostic (3.83e-1)" "unprognostic (1.09e-1)" "unprognostic (8.12e-2)" "unprognostic (3.72e-2)" "potential prognostic unfavorable (9.56e-4)" "unprognostic (4.00e-1)" "unprognostic (1.21e-2)" "unprognostic (2.38e-1)" "unprognostic (7.78e-2)" "unprognostic (1.61e-1)" "unprognostic (6.66e-2)" "unprognostic (2.48e-1)" "unprognostic (3.35e-1)" PTPRCAP "CD45-AP, LPAP" ENSG00000213402 "Protein tyrosine phosphatase receptor type C associated protein" Q14761 11 67435510-67437682 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "intestine: 112.6;lymphoid tissue: 253.8" "Cell type enhanced" "Detected in some" "Astrocytes: 5.3;B-cells: 8.4;Bergmann glia: 5.0;Choroid plexus epithelial cells: 1.8;Ependymal cells: 2.6;Microglia: 7.4;NK-cells: 12.4;Oligodendrocyte progenitor cells: 1.9;Oligodendrocytes: 3.9;T-cells: 6.6" "Cell type enriched" "Detected in many" 28 "leukocyte: 248.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 111 "Leukemia: 246.1;lymphoma: 323.7;Myeloma: 81.4" "Region enhanced" "Detected in single" "basal ganglia: 1.0" "Low region specificity" "Detected in many" HPA043734 Enhanced Approved "Plasma membrane" "Intracellular and membrane" "No annotated function" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 18: Non-specific - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 102: Non-specific - Mixed function" 7 "Plasma membrane" "HPA043734: " "unprognostic (3.73e-2)" "unprognostic (3.05e-3)" "unprognostic (1.88e-2)" "unprognostic (1.02e-2)" "unprognostic (1.66e-1)" "unprognostic (1.48e-1)" "unprognostic (6.57e-3)" "unprognostic (2.52e-3)" "potential prognostic favorable (4.90e-6)" "unprognostic (2.39e-1)" "unprognostic (6.22e-2)" "unprognostic (7.33e-2)" "unprognostic (9.25e-2)" "unprognostic (1.33e-2)" "unprognostic (1.80e-2)" "unprognostic (3.04e-2)" "unprognostic (6.86e-2)" "unprognostic (1.35e-1)" "unprognostic (5.12e-2)" "unprognostic (3.63e-2)" "unprognostic (4.07e-3)" "unprognostic (1.16e-1)" "unprognostic (1.99e-1)" "unprognostic (2.72e-1)" "unprognostic (2.06e-2)" "unprognostic (1.91e-1)" "potential prognostic favorable (9.82e-4)" "unprognostic (1.77e-1)" "unprognostic (2.09e-1)" "unprognostic (3.61e-2)" "unprognostic (4.05e-2)" PTPRD "HPTP, PTPD" ENSG00000153707 "Protein tyrosine phosphatase receptor type D" P23468 9 8314246-10613002 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 39.1;parathyroid gland: 17.4" "Cell type enhanced" "Detected in many" "Bergmann glia: 991.7;Brain excitatory neurons: 3295.3;Brain inhibitory neurons: 1486.8;Lactotrophs: 1829.1;Oligodendrocyte progenitor cells: 1371.2;Oligodendrocytes: 3272.7;Other brain neurons: 1914.2;Podocytes: 2179.7;Proximal tubule cells: 837.9;Retinal amacrine cells: 868.8;Retinal bipolar cells: 1019.7;Retinal ganglion cells: 1004.3;Somatotrophs: 1403.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 6.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 21.5" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Kidney - Proximal tubular cells, Pituitary gland - Lactotropes, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054829 Uncertain Approved Nucleoplasm,Vesicles "Intracellular and membrane" Receptor NA NA 4400000 "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 5: Rhabdoid - Unknown function" "Cluster 109: Neurons - Neuronal signaling" 8 Vesicles Nucleoplasm "HPA054829: " "unprognostic (3.65e-2)" "unprognostic (7.39e-3)" "potential prognostic favorable (7.50e-5)" "unprognostic (3.68e-1)" "unprognostic (2.10e-2)" "unprognostic (2.07e-1)" "unprognostic (8.79e-2)" "unprognostic (3.93e-2)" "unprognostic (1.13e-2)" "potential prognostic favorable (6.52e-4)" "unprognostic (4.33e-1)" "unprognostic (1.18e-1)" "unprognostic (1.47e-2)" "unprognostic (5.33e-3)" "unprognostic (2.50e-2)" "unprognostic (1.24e-1)" PTPRE PTPE ENSG00000132334 "Protein tyrosine phosphatase receptor type E" P23469 10 127907103-128085855 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 44.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 505.7;cDC: 465.2;Lymphatic endothelial cells: 746.2;Macrophages: 380.0;Microglia: 623.5;monocytes: 700.0;Neutrophil progenitors: 511.4;Neutrophils: 1931.9;Oligodendrocyte progenitor cells: 390.9;pDCs: 527.6" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 787.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 643.1;plasmacytoid DC: 478.1" "Group enriched" "Detected in all" 12 "dendritic cells: 478.1;granulocytes: 643.1;monocytes: 177.0" "Low cancer specificity" "Detected in many" "Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015870, HPA021872" Supported Approved "Intermediate filaments" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 51: Neurons - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 8 "Intermediate filaments" "HPA015870: , HPA021872: " "unprognostic (2.60e-1)" "unprognostic (2.15e-1)" "unprognostic (4.87e-2)" "unprognostic (1.70e-2)" "unprognostic (2.26e-1)" "unprognostic (2.32e-1)" "unprognostic (3.67e-1)" "unprognostic (1.15e-1)" "unprognostic (1.90e-2)" "unprognostic (7.03e-2)" "potential prognostic favorable (8.05e-4)" "unprognostic (4.19e-3)" "unprognostic (1.13e-1)" "unprognostic (2.66e-2)" "unprognostic (8.74e-2)" "unprognostic (1.88e-2)" "unprognostic (2.99e-2)" "unprognostic (6.00e-3)" "unprognostic (8.69e-2)" "unprognostic (7.69e-3)" "unprognostic (1.59e-3)" "unprognostic (5.36e-2)" "potential prognostic unfavorable (1.97e-5)" "unprognostic (1.30e-1)" "unprognostic (3.57e-1)" "unprognostic (7.13e-3)" "unprognostic (1.20e-1)" "unprognostic (1.81e-1)" "unprognostic (3.98e-2)" "unprognostic (4.34e-2)" "potential prognostic unfavorable (6.24e-5)" PTPRF LAR ENSG00000142949 "Protein tyrosine phosphatase receptor type F" P10586 1 43525187-43623666 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Heparin-binding, Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 714.2;Goblet cells: 343.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012710 Uncertain Approved "Golgi apparatus" "Intracellular and membrane" Receptor NA NA 65000000 "Cluster 11: Esophagus - Basic cellular processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 70: Intestinal goblet cells - Mucin production" 30 "Golgi apparatus" "HPA012710: " "unprognostic (1.72e-2)" "unprognostic (1.47e-1)" "unprognostic (2.49e-1)" "unprognostic (1.30e-2)" "unprognostic (6.68e-3)" "unprognostic (1.16e-1)" "unprognostic (9.96e-2)" "unprognostic (3.25e-1)" "unprognostic (5.07e-2)" "unprognostic (3.04e-1)" "unprognostic (3.42e-3)" "unprognostic (8.58e-2)" "unprognostic (3.11e-1)" "potential prognostic unfavorable (2.48e-5)" "unprognostic (5.44e-2)" "unprognostic (2.60e-1)" "unprognostic (3.00e-2)" "unprognostic (1.97e-1)" "unprognostic (1.33e-1)" "unprognostic (7.30e-2)" "unprognostic (1.01e-2)" "unprognostic (3.22e-2)" "unprognostic (9.25e-2)" "unprognostic (1.60e-1)" "unprognostic (2.32e-1)" "unprognostic (1.68e-2)" "unprognostic (6.44e-2)" "unprognostic (1.35e-3)" "unprognostic (4.29e-1)" "unprognostic (4.70e-2)" "unprognostic (1.35e-1)" PTPRG "PTPG, RPTPG" ENSG00000144724 "Protein tyrosine phosphatase receptor type G" P23470 3 61561569-62297609 "Enzymes, Plasma proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 4700.8;Distal convoluted tubule cells: 1727.0;Retinal bipolar cells: 2091.8;Retinal horizontal cells: 1630.7;Retinal pigment epithelial cells: 1581.6" "Cell type enhanced" "Detected in all" "endothelial cell: 5348.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Minor Salivary Gland - Macrophages, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000546, HPA064237" Uncertain Approved "Plasma membrane" NA NA 62000000 "Cluster 75: Ovary - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 6 "Plasma membrane" "HPA000546: , HPA064237: " "unprognostic (3.10e-1)" "unprognostic (7.60e-2)" "unprognostic (1.04e-2)" "unprognostic (1.16e-1)" "unprognostic (1.38e-1)" "unprognostic (2.30e-1)" "unprognostic (8.18e-2)" "unprognostic (9.93e-3)" "unprognostic (1.85e-1)" "unprognostic (1.27e-2)" "validated prognostic favorable (1.48e-10)" "validated prognostic favorable (1.36e-4)" "unprognostic (1.87e-2)" "unprognostic (7.01e-2)" "unprognostic (3.40e-2)" "unprognostic (4.69e-2)" "potential prognostic unfavorable (1.57e-4)" "unprognostic (1.41e-1)" "unprognostic (1.24e-1)" "unprognostic (1.64e-3)" "potential prognostic unfavorable (7.52e-5)" "unprognostic (4.98e-2)" "unprognostic (2.35e-1)" "unprognostic (3.57e-1)" "unprognostic (5.40e-2)" "unprognostic (2.23e-1)" "unprognostic (1.20e-1)" "unprognostic (2.51e-2)" "unprognostic (3.63e-1)" "unprognostic (2.43e-1)" "unprognostic (2.16e-1)" PTPRH SAP-1 ENSG00000080031 "Protein tyrosine phosphatase receptor type H" Q9HD43 19 55181247-55209506 "Enzymes, Predicted membrane proteins" Apoptosis "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 22.8;intestine: 64.6;stomach 1: 22.3" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 28.2;Cholangiocytes: 28.0;Colonocytes: 101.1;Enteric transient amplifying cells: 32.8;Enterocytes: 274.3;Foveolar cells: 78.5;Goblet cells: 38.1;Pancreatic acinar cells: 47.8;Pancreatic duct cells: 29.8;Paneth cells: 61.9" "Cell type enhanced" "Detected in some" "oligodendrocyte: 6.6" "Cancer enhanced" "Detected in many" "Pancreatic Adenocarcinoma (TCGA): 26.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Pituitary gland - Gonadotropes, Prostate - Urothelial cells, Spleen - Endothelial cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA008708 Approved "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 30: White matter - Myelination" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 10 "Nuclear speckles, Cytosol" "Plasma membrane" "HPA008708: " "unprognostic (5.48e-2)" "unprognostic (7.99e-3)" "unprognostic (2.30e-1)" "unprognostic (1.47e-2)" "unprognostic (7.12e-2)" "unprognostic (1.98e-3)" "unprognostic (1.61e-3)" "unprognostic (1.33e-2)" "validated prognostic unfavorable (2.53e-11)" "validated prognostic unfavorable (9.40e-4)" "unprognostic (4.08e-2)" "unprognostic (8.55e-2)" "unprognostic (4.68e-1)" "potential prognostic unfavorable (3.21e-5)" "unprognostic (2.77e-3)" "unprognostic (2.44e-1)" "unprognostic (2.08e-1)" "unprognostic (6.79e-2)" "unprognostic (1.21e-1)" "unprognostic (1.54e-1)" "unprognostic (1.26e-2)" "unprognostic (2.21e-2)" "unprognostic (1.06e-2)" "unprognostic (9.70e-2)" PTPRJ "CD148, DEP1, HPTPeta" ENSG00000149177 "Protein tyrosine phosphatase receptor type J" Q12913 11 47980425-48170839 "CD markers, Enzymes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" Angiogenesis "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglia: 975.6;Neutrophil progenitors: 1712.9;Neutrophils: 3323.0;Proximal tubule cells: 833.2;Renal collecting duct intercalated cells: 1339.7;Tuft cells: 1095.2" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 1249.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 9.5" "Group enriched" "Detected in many" 4 "granulocytes: 9.5;monocytes: 4.8" "Low cancer specificity" "Detected in all" "Adipose visceral - Macrophages, Adrenal gland - Macrophages, Lung - Neutrophils_2, Prostate - Prostate glandular cells, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006026 Approved Approved "Nucleoplasm,Nucleoli,Nuclear bodies,Cell Junctions" "Secreted to blood" Enzyme NA NA 90000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 24: Neutrophils - Innate immunity signal integration" 21 "Nucleoplasm, Cell Junctions" "Nucleoli, Nuclear bodies" "HPA006026: " "unprognostic (2.18e-1)" "unprognostic (1.40e-1)" "unprognostic (6.25e-2)" "unprognostic (2.64e-1)" "unprognostic (1.02e-1)" "unprognostic (1.44e-3)" "unprognostic (8.84e-2)" "unprognostic (1.30e-1)" "unprognostic (5.98e-2)" "unprognostic (1.61e-1)" "potential prognostic favorable (2.50e-4)" "unprognostic (1.91e-2)" "unprognostic (2.12e-1)" "unprognostic (6.02e-2)" "unprognostic (2.39e-1)" "unprognostic (2.70e-1)" "unprognostic (1.94e-2)" "unprognostic (1.54e-1)" "unprognostic (1.51e-1)" "unprognostic (1.04e-2)" "unprognostic (2.07e-2)" "unprognostic (1.19e-1)" "unprognostic (4.01e-1)" "unprognostic (1.37e-1)" "unprognostic (5.64e-2)" "unprognostic (3.10e-1)" "unprognostic (3.31e-2)" "unprognostic (4.55e-2)" "unprognostic (3.22e-2)" "unprognostic (4.98e-2)" "unprognostic (3.13e-1)" PTPRK R-PTP-kappa ENSG00000152894 "Protein tyrosine phosphatase receptor type K" Q15262 6 127968785-128520616 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 229.4;Brain excitatory neurons: 404.3;Brain inhibitory neurons: 254.2;Choroid plexus epithelial cells: 333.4;Distal convoluted tubule cells: 314.4;Ependymal cells: 554.5;Loop of henle epithelial cells: 371.3;Oligodendrocyte progenitor cells: 469.8;Oligodendrocytes: 1524.9;Papillary tip epithelial cells: 531.1;Proximal tubule cells: 622.3;Renal collecting duct intercalated cells: 518.8;Renal collecting duct principal cells: 475.6;Renal connecting tubule cells: 434.8" "Cell type enhanced" "Detected in all" "pericyte: 3521.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 1.6;naive B-cell: 2.9" "Lineage enriched" "Detected in single" 7 "B-cells: 2.9" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054056, HPA054822" Uncertain Supported "Vesicles,Plasma membrane,Cell Junctions,Connecting piece,Flagellar centriole" NA NA 4800000 "Cluster 18: Non-specific - Translation" "Cluster 60: Stomach - Digestion" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 22: Non-specific - Basic cellular functions" 10 "Cell Junctions" "Vesicles, Plasma membrane, Connecting piece, Flagellar centriole" "HPA054056: , HPA054822: " "unprognostic (7.09e-2)" "unprognostic (2.33e-1)" "unprognostic (2.49e-1)" "unprognostic (3.10e-2)" "unprognostic (4.87e-3)" "unprognostic (2.23e-2)" "unprognostic (1.07e-1)" "unprognostic (2.14e-2)" "unprognostic (8.02e-2)" "unprognostic (6.36e-2)" "validated prognostic favorable (5.57e-9)" "validated prognostic favorable (9.10e-5)" "unprognostic (2.55e-1)" "unprognostic (5.64e-1)" "unprognostic (5.82e-3)" "unprognostic (1.23e-1)" "unprognostic (1.68e-2)" "unprognostic (9.56e-2)" "unprognostic (5.09e-2)" "unprognostic (7.76e-3)" "unprognostic (1.15e-3)" "potential prognostic unfavorable (3.10e-4)" "unprognostic (1.49e-1)" "unprognostic (3.71e-1)" "unprognostic (2.81e-3)" "unprognostic (2.99e-1)" "unprognostic (9.52e-2)" "unprognostic (9.47e-2)" "unprognostic (1.78e-1)" "unprognostic (2.58e-1)" "unprognostic (8.51e-3)" PTPRM "hR-PTPu, PTPRL1, RPTPU" ENSG00000173482 "Protein tyrosine phosphatase receptor type M" P28827 18 7566782-8406861 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bergmann glia: 1139.2;Choroid plexus epithelial cells: 1448.8;Endometrial glandular cells: 1120.2;Endometrial luminal cells: 1179.2;Melanocytes: 1194.2;Urothelial cells: 1106.6;Vascular endothelial cells: 1535.2" "Cell type enhanced" "Detected in all" "endothelial cell: 1825.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory CD8 T-cell: 4.7" "Group enriched" "Detected in many" 33 "dendritic cells: 1.8;T-cells: 4.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003891, CAB022442, CAB022443" Supported Enhanced "Plasma membrane,Primary cilium,Primary cilium tip" NA Yes 17000000 "Cluster 30: Non-specific - DNA binding" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 38: Sub-cortical - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 3 "Plasma membrane" "Primary cilium, Primary cilium tip" "CAB022442: , CAB022443: , HPA003891: " "unprognostic (2.99e-3)" "unprognostic (1.85e-1)" "unprognostic (2.03e-1)" "potential prognostic unfavorable (1.42e-4)" "unprognostic (8.76e-2)" "unprognostic (3.26e-2)" "unprognostic (1.83e-1)" "unprognostic (7.55e-3)" "unprognostic (2.19e-1)" "unprognostic (4.95e-2)" "validated prognostic favorable (1.92e-9)" "validated prognostic favorable (3.76e-5)" "unprognostic (7.14e-2)" "unprognostic (2.15e-1)" "potential prognostic favorable (6.55e-4)" "unprognostic (2.44e-1)" "unprognostic (1.17e-1)" "unprognostic (4.61e-2)" "unprognostic (1.58e-1)" "unprognostic (8.29e-2)" "unprognostic (9.36e-2)" "unprognostic (4.17e-2)" "unprognostic (1.86e-2)" "unprognostic (7.57e-2)" "unprognostic (1.30e-1)" "unprognostic (2.33e-2)" "unprognostic (2.48e-1)" "unprognostic (1.31e-3)" "unprognostic (3.39e-2)" "unprognostic (1.79e-1)" "unprognostic (2.06e-1)" PTPRN "IA-2, ICA512" ENSG00000054356 "Protein tyrosine phosphatase receptor type N" Q16849 2 219289623-219309648 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" Receptor "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 157.2;pituitary gland: 178.0" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 63.8;Brain excitatory neurons: 64.2;Brain inhibitory neurons: 81.9;Corticotrophs: 50.7;Gonadotrophs: 125.3;Lactotrophs: 112.2;Other brain neurons: 111.8;Pancreatic islet cells: 617.8;Platelets: 57.7;Retinal amacrine cells: 52.2;Somatotrophs: 163.1" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 9 "Glioblastoma Multiforme (TCGA): 22.5;Pancreatic Adenocarcinoma (TCGA): 72.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 41.9;thyroid cancer: 38.6" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Stomach - Gastric enteroendocrine cells, Thyroid gland - Parafollicular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007152, HPA007179" Enhanced Uncertain "Endoplasmic reticulum" NA NA 11000 "Cluster 10: Brain - Synaptic signal transduction" "Cluster 1: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 48 "Endoplasmic reticulum" "HPA007152: , HPA007179: " "unprognostic (3.37e-1)" "unprognostic (5.03e-1)" "potential prognostic unfavorable (5.99e-4)" "unprognostic (5.67e-2)" "potential prognostic unfavorable (1.56e-8)" "unprognostic (1.48e-2)" "unprognostic (2.11e-2)" "unprognostic (5.02e-2)" "potential prognostic unfavorable (3.57e-4)" "unprognostic (2.55e-3)" "unprognostic (7.72e-3)" "unprognostic (2.65e-2)" "unprognostic (3.09e-2)" "unprognostic (1.98e-2)" "unprognostic (9.83e-3)" "unprognostic (8.82e-2)" "unprognostic (3.47e-1)" "unprognostic (4.30e-2)" "unprognostic (2.13e-1)" PTPRN2 "IA-2beta, ICAAR, KIAA0387, phogrin" ENSG00000155093 "Protein tyrosine phosphatase receptor type N2" Q92932 7 157539056-158587823 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid metabolism, Phospholipid metabolism" "Hydrolase, Protein phosphatase, Receptor" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 60.1;pancreas: 92.5" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 608.0;Brain inhibitory neurons: 788.4;Corticotrophs: 491.7;Gonadotrophs: 910.6;Lactotrophs: 836.1;Neuroendocrine cells: 573.4;Other brain neurons: 691.5;Pancreatic islet cells: 538.8;Somatotrophs: 827.5;Thyrotrophs: 732.5" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 61.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 23.7" "Lineage enriched" "Detected in all" 4 "granulocytes: 23.7" "Cancer enhanced" "Detected in many" "thyroid cancer: 34.0" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Lactotropes, Prostate - Prostate glandular cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006900, HPA007255, HPA026656" Enhanced Approved Vesicles NA NA 10000000 "Cluster 35: Neutrophils - Protein binding" "Cluster 36: Brain & Liver - Signaling" "Cluster 51: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 2 Vesicles "HPA006900: , HPA007255: , HPA026656: " "unprognostic (3.40e-3)" "unprognostic (1.96e-1)" "unprognostic (4.84e-1)" "unprognostic (1.78e-1)" "unprognostic (1.85e-1)" "unprognostic (1.88e-3)" "potential prognostic unfavorable (8.03e-5)" "unprognostic (3.16e-1)" "unprognostic (7.66e-3)" "unprognostic (3.13e-3)" "potential prognostic favorable (2.46e-5)" "unprognostic (2.50e-2)" "unprognostic (1.11e-3)" "unprognostic (2.33e-1)" "potential prognostic favorable (4.13e-4)" "unprognostic (8.23e-2)" "unprognostic (4.34e-3)" "unprognostic (1.96e-2)" "unprognostic (4.28e-2)" "unprognostic (1.34e-1)" "unprognostic (1.27e-2)" "unprognostic (2.53e-2)" "unprognostic (1.51e-1)" "unprognostic (1.13e-1)" "unprognostic (4.32e-2)" "unprognostic (1.23e-2)" "unprognostic (7.74e-2)" "unprognostic (3.46e-3)" "unprognostic (3.04e-1)" PTPRO "GLEPP1, NPHS6, PTP-oc, PTP-U2, PTPU2" ENSG00000151490 "Protein tyrosine phosphatase receptor type O" Q16827 12 15322257-15602175 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.0;intestine: 25.2;kidney: 32.0" "Cell type enriched" "Detected in many" 20 "Podocytes: 8870.9" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Colon Adenocarcinoma (TCGA): 24.5;Glioblastoma Multiforme (TCGA): 13.8;Kidney Renal Papillary Cell Carcinoma (TCGA): 7.1;Rectum Adenocarcinoma (TCGA): 23.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "colorectal cancer: 9.0;Gastric cancer: 5.9" "Adipose subcutaneous - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Heart muscle - Macrophages, Kidney - Podocytes, Liver - Kupffer cells, Minor Salivary Gland - Macrophages, Pituitary gland - Corticotropes" "Region enhanced" "Detected in all" "olfactory bulb: 175.9" "Low region specificity" "Detected in all" HPA034525 Enhanced "Intracellular and membrane" Receptor NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 72: Kidney - Transmembrane transport" "Cluster 51: Neurons - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 57: Podocytes - Glomerular filtration" 35 "HPA034525: " "unprognostic (1.06e-1)" "unprognostic (9.54e-2)" "unprognostic (4.12e-1)" "unprognostic (5.07e-2)" "unprognostic (2.97e-1)" "unprognostic (1.90e-1)" "unprognostic (9.39e-2)" "unprognostic (1.83e-2)" "unprognostic (2.66e-2)" "unprognostic (4.96e-3)" "unprognostic (3.55e-1)" "unprognostic (3.25e-3)" "unprognostic (3.91e-1)" "unprognostic (1.63e-2)" "unprognostic (1.05e-2)" "unprognostic (1.12e-1)" "unprognostic (1.98e-1)" "unprognostic (4.47e-2)" "unprognostic (1.05e-2)" "unprognostic (1.59e-1)" "unprognostic (1.65e-2)" "unprognostic (3.43e-2)" "unprognostic (2.26e-1)" "unprognostic (1.70e-1)" "unprognostic (1.42e-2)" "unprognostic (1.33e-1)" PTPRQ DFNB84 ENSG00000139304 "Protein tyrosine phosphatase receptor type Q" 12 80402178-80680273 "Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "kidney: 7.8;urinary bladder: 4.6" "Cell type enriched" "Detected in many" 16 "Podocytes: 9487.7" "Cell type enhanced" "Detected in many" "eccentric medium spiny neuron: 99.9;ependymal cell: 262.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 6.5" "Adipose visceral - Mesothelial cells, Kidney - Podocytes, Lung - Alveolar cells type 1, Skin - Sebaceous gland cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA053245 Uncertain Approved Cytosol No NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 33: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 57: Podocytes - Glomerular filtration" Cytosol "HPA053245: " "potential prognostic unfavorable (8.09e-4)" PTPRR "EC-PTP, PCPTP1, PTP-SL, PTPBR7, PTPRQ" ENSG00000153233 "Protein tyrosine phosphatase receptor type R" Q15256 12 70638073-70920738 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 12.1;endometrium 1: 5.2;intestine: 7.2" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 159.6;Brain excitatory neurons: 377.5;Brain inhibitory neurons: 212.4;Colonocytes: 137.3;Enterocytes: 122.3;Foveolar cells: 163.5;Other brain neurons: 154.8;Retinal amacrine cells: 249.4;Retinal bipolar cells: 269.9;Retinal horizontal cells: 272.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 12.2;ovarian cancer: 10.4" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Stomach - Gastric mucous cells" "Region enriched" "Detected in all" 5 "cerebellum: 89.6" "Low region specificity" "Detected in all" "CAB011461, HPA011851, HPA071067" Uncertain Supported "Plasma membrane,Cell Junctions,Cytosol" "Secreted - unknown location" Receptor NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 35: Non-specific - DNA binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 19 "Plasma membrane, Cell Junctions, Cytosol" "CAB011461: , HPA011851: , HPA071067: " "unprognostic (7.24e-2)" "unprognostic (3.85e-2)" "unprognostic (6.65e-2)" "unprognostic (2.29e-1)" "unprognostic (1.61e-1)" "unprognostic (4.07e-2)" "unprognostic (1.90e-2)" "potential prognostic unfavorable (8.04e-4)" "unprognostic (4.19e-1)" "unprognostic (4.83e-1)" "unprognostic (1.58e-1)" "unprognostic (2.95e-1)" "unprognostic (7.70e-2)" PTPRS ENSG00000105426 "Protein tyrosine phosphatase receptor type S" Q13332 19 5158495-5340812 "Enzymes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Heparin-binding, Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 476.7;Hepatic stellate cells: 296.9;pDCs: 589.9;Retinal amacrine cells: 356.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 197 "plasmacytoid DC: 153.7" "Lineage enriched" "Detected in single" 197 "dendritic cells: 153.7" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054747 Approved "Plasma membrane,Cytosol" "Secreted - unknown location" Receptor NA NA 41000000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 64: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 108: Fibroblasts - ECM organization" 9 "Plasma membrane, Cytosol" "HPA054747: " "unprognostic (9.17e-2)" "unprognostic (1.03e-1)" "unprognostic (3.81e-3)" "unprognostic (2.85e-1)" "unprognostic (2.44e-1)" "unprognostic (1.84e-1)" "unprognostic (2.03e-1)" "unprognostic (2.97e-3)" "unprognostic (4.25e-2)" "unprognostic (5.69e-2)" "unprognostic (3.19e-2)" "potential prognostic favorable (5.70e-4)" "unprognostic (9.04e-2)" "unprognostic (1.89e-2)" "unprognostic (1.20e-2)" "unprognostic (1.81e-1)" "unprognostic (3.42e-2)" "unprognostic (1.46e-1)" "unprognostic (1.14e-3)" "unprognostic (6.01e-2)" "unprognostic (1.47e-1)" "unprognostic (4.95e-3)" "unprognostic (1.22e-1)" "unprognostic (1.49e-1)" "unprognostic (1.38e-1)" "unprognostic (2.96e-2)" "unprognostic (5.48e-2)" "unprognostic (4.30e-1)" "unprognostic (1.89e-1)" "unprognostic (2.15e-2)" "unprognostic (2.99e-1)" PTPRT "KIAA0283, RPTPrho" ENSG00000196090 "Protein tyrosine phosphatase receptor type T" O14522 20 42072752-43189970 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 13.8;fallopian tube: 10.2;lymphoid tissue: 5.9" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 594.5;Oligodendrocyte progenitor cells: 826.3;Pancreatic acinar cells: 535.6;Pancreatic islet cells: 366.7;Pituicytes/FSCs: 3596.7;Respiratory ciliated cells: 1599.0;Retinal bipolar cells: 495.2;Salivary myoepithelial cells: 653.2;Tuft cells: 991.4" "Cell type enhanced" "Detected in all" "LAMP5-LHX6 and Chandelier: 2036.9" "Group enriched" "Detected in some" 4 "Breast Invasive Carcinoma (TCGA): 9.3;Prostate Adenocarcinoma (TCGA): 3.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lymphoma: 1.0;Sarcoma: 2.3" "Adipose visceral - Mesothelial cells, Liver - Sinusoid Endothelial cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017336, CAB069423" Approved NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 3 "CAB069423: , HPA017336: " "unprognostic (3.65e-2)" "unprognostic (2.44e-2)" "unprognostic (3.50e-2)" "unprognostic (2.61e-3)" "unprognostic (2.17e-2)" "unprognostic (1.40e-2)" "unprognostic (1.02e-1)" "unprognostic (2.87e-3)" PTPRU "FMI, hPTP-J, PCP-2, PTP, PTPRO" ENSG00000060656 "Protein tyrosine phosphatase receptor type U" Q92729 1 29236516-29326813 "Enzymes, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Differentiation" "Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Papillary tip epithelial cells: 52.3;Respiratory basal cells: 60.5;Rod photoreceptor cells: 80.0;Salivary duct cells: 66.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB011476, HPA039832" Approved NA NA "Cluster 24: Non-specific - Transcription" "Cluster 24: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 4 "CAB011476: , HPA039832: " "unprognostic (2.12e-2)" "unprognostic (5.35e-2)" "unprognostic (7.67e-2)" "unprognostic (2.48e-1)" "unprognostic (2.38e-2)" "unprognostic (8.39e-2)" "unprognostic (3.10e-3)" "unprognostic (5.08e-3)" "unprognostic (3.72e-3)" "unprognostic (1.65e-2)" "unprognostic (1.80e-2)" "potential prognostic favorable (9.01e-5)" "unprognostic (3.32e-1)" "unprognostic (2.46e-1)" "unprognostic (3.98e-2)" "unprognostic (4.54e-2)" "unprognostic (3.23e-1)" "unprognostic (1.46e-3)" "unprognostic (6.66e-2)" "unprognostic (5.37e-3)" "unprognostic (7.16e-2)" "unprognostic (2.18e-3)" "unprognostic (6.33e-2)" "unprognostic (8.59e-2)" "potential prognostic unfavorable (6.38e-4)" "unprognostic (3.73e-3)" "unprognostic (1.63e-1)" "unprognostic (1.29e-1)" "unprognostic (1.51e-1)" "unprognostic (7.47e-2)" "unprognostic (6.86e-2)" PTPRZ1 "phosphacan, PTP18, PTPRZ, PTPZ, RPTPB" ENSG00000106278 "Protein tyrosine phosphatase receptor type Z1" P23471 7 121873089-122062036 "Enzymes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 150.5" "Cell type enhanced" "Detected in many" "Astrocytes: 981.3;Bergmann glia: 1581.8;Ependymal cells: 517.8;Oligodendrocyte progenitor cells: 3945.7;Respiratory basal cells: 456.9" "Cell type enhanced" "Detected in all" "Bergmann glia: 1831.5;oligodendrocyte precursor cell: 4812.8" "Cancer enriched" "Detected in many" 17 "Glioblastoma Multiforme (TCGA): 591.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Esophageal cancer: 21.7;skin cancer: 27.8" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Prostate - Urothelial cells, Skin - Keratinocyte (other), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015103 Enhanced Approved Vesicles,Cytosol "Secreted in brain" Enzyme NA NA 7400000 "Cluster 73: Brain - Neuronal signaling" "Cluster 21: Non-specific - Metabolism" "Cluster 69: Skin cancer - ECM organization" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 9 Cytosol Vesicles "HPA015103: " "unprognostic (2.48e-2)" "potential prognostic favorable (5.25e-6)" "unprognostic (1.42e-1)" "potential prognostic favorable (9.67e-4)" "unprognostic (1.62e-1)" "unprognostic (1.93e-2)" "unprognostic (3.28e-2)" "unprognostic (3.88e-3)" "unprognostic (4.53e-2)" "unprognostic (7.98e-2)" "unprognostic (5.94e-2)" "unprognostic (1.24e-3)" "unprognostic (1.08e-1)" "unprognostic (8.65e-2)" "unprognostic (3.20e-1)" "unprognostic (3.94e-1)" "unprognostic (2.13e-1)" PTRH1 "C9orf115, PTH1" ENSG00000187024 "Peptidyl-tRNA hydrolase 1 homolog" Q86Y79 9 127690348-127724873 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, RNA-binding, tRNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 127.8;Epicardial cells: 113.7;Epididymal efferent duct absorptive cells: 106.1;Peritubular myoid cells: 83.7;Respiratory ciliated cells: 100.9" "Cell type enhanced" "Detected in all" "ependymal cell: 81.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021223 Uncertain NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 12 "HPA021223: " "unprognostic (1.25e-2)" "unprognostic (4.23e-1)" "unprognostic (2.56e-2)" "unprognostic (1.50e-1)" "unprognostic (2.27e-2)" "unprognostic (2.27e-2)" "unprognostic (2.62e-3)" "unprognostic (3.20e-1)" "unprognostic (5.34e-2)" "unprognostic (1.11e-1)" "unprognostic (7.37e-2)" "unprognostic (1.01e-1)" "potential prognostic favorable (8.48e-7)" "unprognostic (4.48e-3)" "unprognostic (6.27e-2)" "unprognostic (1.23e-1)" "unprognostic (1.06e-1)" "unprognostic (2.69e-3)" "unprognostic (1.72e-1)" "unprognostic (4.33e-2)" "unprognostic (8.11e-2)" "unprognostic (3.56e-2)" "unprognostic (1.29e-1)" "unprognostic (6.56e-3)" "unprognostic (1.45e-1)" "unprognostic (5.02e-2)" "unprognostic (6.04e-2)" "unprognostic (1.37e-1)" "unprognostic (3.52e-1)" "unprognostic (4.21e-1)" "unprognostic (1.48e-3)" PTRH2 "BIT1, CFAP37, CGI-147, PTH2" ENSG00000141378 "Peptidyl-tRNA hydrolase 2" Q9Y3E5 17 59674636-59707626 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" Apoptosis Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 203.0;Epicardial cells: 229.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012897 Supported Supported Mitochondria NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 22: Epididymis - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 27 Mitochondria "HPA012897: " "unprognostic (2.28e-2)" "unprognostic (1.04e-1)" "unprognostic (1.14e-1)" "unprognostic (1.40e-1)" "unprognostic (1.59e-2)" "unprognostic (2.17e-1)" "unprognostic (3.44e-2)" "unprognostic (1.28e-1)" "unprognostic (2.12e-2)" "unprognostic (1.76e-2)" "unprognostic (7.04e-2)" "unprognostic (3.27e-1)" "potential prognostic unfavorable (7.75e-5)" "validated prognostic unfavorable (1.66e-5)" "validated prognostic unfavorable (1.38e-4)" "unprognostic (4.99e-3)" "unprognostic (3.50e-3)" "unprognostic (1.97e-2)" "unprognostic (7.58e-2)" "unprognostic (7.66e-3)" "unprognostic (1.56e-1)" "unprognostic (2.01e-1)" "unprognostic (2.19e-1)" "unprognostic (1.26e-1)" "unprognostic (3.75e-2)" "unprognostic (7.57e-2)" "unprognostic (2.37e-1)" "unprognostic (7.98e-2)" "unprognostic (1.52e-1)" "unprognostic (1.81e-1)" "unprognostic (1.29e-1)" PTRHD1 "C2orf79, LOC391356" ENSG00000184924 "Peptidyl-tRNA hydrolase domain containing 1" Q6GMV3 2 24789728-24793391 "Enzymes, Predicted intracellular proteins" Hydrolase "Intellectual disability, Parkinsonism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 238.7;Esophageal apical cells: 245.9;Esophageal suprabasal cells: 266.5;Late primary spermatocytes: 332.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019951 Approved Approved Nucleoplasm NA NA 60000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 97: Non-specific - Cellular respiration" 3 Nucleoplasm "HPA019951: " "unprognostic (1.62e-2)" "unprognostic (2.07e-3)" "unprognostic (4.89e-2)" "unprognostic (3.98e-1)" "unprognostic (3.44e-2)" "unprognostic (6.99e-2)" "unprognostic (1.10e-2)" "unprognostic (2.91e-1)" "unprognostic (6.11e-2)" "unprognostic (1.44e-2)" "unprognostic (1.54e-3)" "unprognostic (2.62e-1)" "unprognostic (1.45e-2)" "potential prognostic unfavorable (6.05e-4)" "unprognostic (3.42e-1)" "unprognostic (3.68e-2)" "unprognostic (8.78e-2)" "unprognostic (1.51e-1)" "unprognostic (7.33e-3)" "unprognostic (9.76e-2)" "unprognostic (8.43e-2)" "unprognostic (1.82e-1)" "unprognostic (1.86e-1)" "unprognostic (2.90e-2)" "unprognostic (2.62e-1)" "unprognostic (6.14e-2)" "unprognostic (1.68e-1)" "unprognostic (3.28e-1)" "unprognostic (1.93e-1)" "unprognostic (3.70e-1)" PTS PTPS ENSG00000150787 "6-pyruvoyltetrahydropterin synthase" Q03393 11 112226367-112269955 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Tetrahydrobiopterin biosynthesis" Lyase "Disease variant, Phenylketonuria" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 341.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001481 Uncertain Approved Cytosol NA NA 4400 "Cluster 24: Non-specific - Transcription" "Cluster 76: Non-specific - Metabolism" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 85: Squamous epithelial cells - Keratinization" 8 Cytosol "HPA001481: " "unprognostic (1.46e-1)" "unprognostic (2.85e-3)" "unprognostic (9.09e-2)" "unprognostic (8.14e-2)" "unprognostic (1.28e-1)" "unprognostic (6.50e-2)" "unprognostic (1.80e-1)" "unprognostic (2.83e-2)" "unprognostic (1.08e-2)" "unprognostic (2.85e-2)" "unprognostic (1.43e-1)" "unprognostic (3.29e-1)" "unprognostic (1.67e-2)" "unprognostic (2.47e-2)" "unprognostic (6.39e-3)" "unprognostic (1.85e-3)" "unprognostic (3.38e-2)" "unprognostic (1.61e-2)" "unprognostic (2.95e-1)" "unprognostic (2.74e-2)" "unprognostic (4.79e-2)" "unprognostic (2.92e-2)" "unprognostic (3.99e-2)" "unprognostic (3.17e-1)" "unprognostic (7.75e-2)" "unprognostic (6.42e-2)" "unprognostic (3.56e-2)" "unprognostic (3.08e-2)" "unprognostic (1.48e-1)" "unprognostic (5.51e-3)" "unprognostic (1.19e-1)" PTTG1 "EAP1, ECRAR, HPTTG, PTTG, securin, TUTR1" ENSG00000164611 "PTTG1 regulator of sister chromatid separation, securin" O95997 5 160421855-160428739 "Cancer-related genes, Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, DNA damage, DNA repair, Mitosis" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 150.9;lymphoid tissue: 135.4;testis: 163.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 253.1;Early spermatids: 622.6;Enteric transient amplifying cells: 201.8;Esophageal basal cells: 520.4;Extravillous trophoblasts: 201.3;Gastric progenitor cells: 307.6;Late primary spermatocytes: 1846.1;Oocytes: 336.2" "Cell type enhanced" "Detected in many" "miscellaneous: 14.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "T-reg: 218.7" "Lineage enriched" "Detected in all" 7 "T-cells: 218.7" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "CAB008373, HPA008890, HPA045034" Enhanced Supported Nucleoli,Cytosol NA Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 29: Forebrain - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Non-specific - Cell proliferation" 21 Cytosol Nucleoli "CAB008373: , HPA008890: , HPA045034: " "potential prognostic unfavorable (8.85e-4)" "unprognostic (1.25e-2)" "unprognostic (9.01e-2)" "potential prognostic favorable (2.55e-4)" "unprognostic (2.27e-2)" "unprognostic (2.57e-1)" "unprognostic (4.46e-2)" "unprognostic (4.04e-1)" "unprognostic (1.61e-1)" "unprognostic (9.24e-3)" "validated prognostic unfavorable (4.09e-12)" "validated prognostic unfavorable (1.24e-5)" "potential prognostic unfavorable (2.70e-7)" "validated prognostic unfavorable (3.52e-8)" "validated prognostic unfavorable (1.00e-9)" "potential prognostic unfavorable (2.89e-5)" "unprognostic (1.01e-3)" "unprognostic (2.46e-2)" "unprognostic (3.53e-1)" "unprognostic (7.87e-2)" "unprognostic (4.09e-2)" "potential prognostic unfavorable (2.97e-4)" "unprognostic (2.79e-3)" "unprognostic (8.96e-2)" "unprognostic (2.02e-1)" "unprognostic (6.13e-2)" "unprognostic (1.22e-1)" "unprognostic (3.96e-2)" "unprognostic (2.28e-1)" "unprognostic (1.11e-2)" "unprognostic (1.22e-1)" PTTG1IP "C21orf1, C21orf3, PBF, PTTG1IP1" ENSG00000183255 "PTTG1 interacting protein" P53801 21 44849585-44873903 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Platelets: 436.9;Syncytiotrophoblasts: 470.5" "Cell type enhanced" "Detected in all" "endothelial cell: 181.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Lung - Endothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "CAB034146, HPA061827" Uncertain Supported Nucleoplasm NA Yes 12000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 30 Nucleoplasm "CAB034146: , HPA061827: " "unprognostic (1.89e-1)" "unprognostic (9.54e-3)" "unprognostic (2.21e-1)" "potential prognostic unfavorable (9.21e-4)" "unprognostic (2.00e-1)" "unprognostic (2.35e-1)" "unprognostic (2.04e-1)" "unprognostic (1.49e-1)" "unprognostic (9.11e-3)" "unprognostic (2.62e-2)" "potential prognostic favorable (1.21e-4)" "unprognostic (2.39e-1)" "unprognostic (2.91e-1)" "unprognostic (3.07e-2)" "unprognostic (8.78e-2)" "unprognostic (1.48e-3)" "unprognostic (9.94e-3)" "potential prognostic unfavorable (9.65e-4)" "unprognostic (1.01e-1)" "unprognostic (1.70e-2)" "unprognostic (3.56e-2)" "unprognostic (2.66e-3)" "unprognostic (5.35e-2)" "unprognostic (3.46e-1)" "unprognostic (8.05e-2)" "unprognostic (1.45e-1)" "unprognostic (3.02e-2)" "unprognostic (2.09e-3)" "unprognostic (6.73e-2)" "unprognostic (1.49e-1)" "unprognostic (2.40e-1)" PTTG1IP2 ENSG00000251154 "PTTG1IP family member 2" P0DTF9 7 90469639-90513397 "Essential proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 123 "testis: 12.3" "Group enriched" "Detected in some" 19 "Early spermatids: 52.2;Late primary spermatocytes: 50.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" PTTG2 ENSG00000250254 "Pituitary tumor-transforming 2" Q9NZH5 4 37960398-37961128 "Predicted intracellular proteins" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA008890, HPA045034" Uncertain Approved Nucleoli,Cytosol NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 9: Non-specific - Receptor signaling" Cytosol Nucleoli "HPA008890: , HPA045034: " PTX3 "TNFAIP5, TSG-14" ENSG00000163661 "Pentraxin 3" P26022 3 157436850-157443633 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 230.2;urinary bladder: 177.9" "Cell type enhanced" "Detected in many" "Endometrial luminal cells: 37.7;Fallopian secretory cells: 90.2;Fibroblasts: 91.7;Lymphatic endothelial cells: 74.7;monocytes: 134.3;Neutrophil progenitors: 185.4;Neutrophils: 79.3;Pancreatic duct cells: 37.1;Schwann cells: 64.4" "Cell type enhanced" "Detected in some" "hippocampal CA4: 5.2;lower rhombic lip: 5.8" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 39.1" "Region enhanced" "Detected in many" "thalamus: 9.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 203.9" "Colon - Neutrophils, Skin - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA069320 Approved Uncertain "Plasma membrane" "Secreted to blood" "No annotated function" NA NA 1090000 6900000 "Cluster 19: Eosinophils - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 12: Non-specific - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 10 "Plasma membrane" "HPA069320: " "unprognostic (2.63e-1)" "unprognostic (1.02e-2)" "unprognostic (3.91e-2)" "unprognostic (1.61e-2)" "unprognostic (2.48e-1)" "unprognostic (4.71e-3)" "potential prognostic unfavorable (3.34e-5)" "potential prognostic unfavorable (1.67e-4)" "unprognostic (2.55e-2)" "potential prognostic unfavorable (3.77e-7)" "unprognostic (1.56e-1)" "unprognostic (2.10e-1)" "unprognostic (2.11e-3)" "potential prognostic unfavorable (2.01e-4)" "potential prognostic unfavorable (4.21e-5)" "unprognostic (4.90e-2)" "unprognostic (6.68e-2)" "unprognostic (3.32e-1)" "unprognostic (6.61e-2)" "potential prognostic unfavorable (2.29e-4)" "unprognostic (2.17e-1)" "unprognostic (5.29e-2)" "unprognostic (3.99e-2)" "potential prognostic unfavorable (2.12e-5)" PTX4 C16orf38 ENSG00000251692 "Pentraxin 4" Q96A99 16 1485886-1488981 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "Leukemia: 1.1" "Adrenal gland - Adrenal cortex cells" "Region enhanced" "Detected in single" "hypothalamus: 1.0" "Low region specificity" "Detected in all" HPA073694 Supported "Secreted - unknown location" "No annotated function" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 46: Brainstem - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" "HPA073694: " PUDP "DXF68S1E, FAM16AX, GS1, HDHD1, HDHD1A" ENSG00000130021 "Pseudouridine 5'-phosphatase" Q08623 X 6667865-7148158 "Enzymes, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA000292, HPA072672" Approved Approved Nucleoplasm,Cytosol NA NA 170000 "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 36: Non-specific - mRNA processing" "Cluster 7: Non-specific - Transcription" 27 Nucleoplasm Cytosol "HPA000292: , HPA072672: " "unprognostic (6.66e-2)" "unprognostic (5.09e-2)" "unprognostic (2.84e-2)" "potential prognostic favorable (3.55e-4)" "unprognostic (4.95e-2)" "unprognostic (2.96e-1)" "unprognostic (1.36e-2)" "unprognostic (1.56e-2)" "unprognostic (3.37e-3)" "unprognostic (3.28e-3)" "unprognostic (3.61e-2)" "unprognostic (1.22e-1)" "potential prognostic unfavorable (7.23e-4)" "unprognostic (1.02e-1)" "unprognostic (2.94e-3)" "unprognostic (1.98e-2)" "unprognostic (1.16e-2)" "unprognostic (2.39e-1)" "unprognostic (4.40e-1)" "potential prognostic unfavorable (4.19e-5)" "unprognostic (4.44e-1)" "unprognostic (3.25e-1)" "unprognostic (2.55e-1)" "unprognostic (2.08e-2)" "unprognostic (3.58e-2)" "unprognostic (1.79e-1)" "unprognostic (4.34e-2)" "unprognostic (4.85e-2)" "unprognostic (9.80e-2)" PUF60 "FIR, RoBPI, SIAHBP1" ENSG00000179950 "Poly(U) binding splicing factor 60" Q9UHX1 8 143816344-143830709 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Apoptosis, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "DNA-binding, Repressor, Ribonucleoprotein, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ependymal cells: 34.0;Late spermatids: 30.4;Oligodendrocytes: 39.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045733, HPA052096, HPA059714" Enhanced Enhanced Nucleoplasm NA NA 35000 "Cluster 33: Non-specific - ATP binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 40: Non-specific - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" 78 Nucleoplasm "HPA045733: , HPA052096: , HPA059714: " "unprognostic (1.82e-1)" "unprognostic (4.42e-2)" "unprognostic (2.13e-1)" "unprognostic (2.80e-2)" "unprognostic (1.48e-1)" "unprognostic (4.36e-2)" "unprognostic (3.28e-2)" "potential prognostic favorable (3.33e-4)" "unprognostic (3.68e-2)" "unprognostic (1.69e-1)" "unprognostic (7.55e-3)" "unprognostic (2.31e-1)" "unprognostic (1.13e-1)" "unprognostic (7.73e-2)" "unprognostic (1.23e-2)" "unprognostic (2.88e-3)" "unprognostic (2.47e-2)" "unprognostic (2.85e-3)" "unprognostic (2.56e-1)" "unprognostic (1.38e-1)" "unprognostic (7.49e-2)" "unprognostic (7.61e-2)" "unprognostic (1.54e-2)" "unprognostic (1.36e-1)" "unprognostic (1.30e-1)" "unprognostic (6.49e-2)" "unprognostic (2.46e-3)" "unprognostic (2.09e-1)" "unprognostic (2.22e-1)" "unprognostic (1.62e-1)" "unprognostic (1.96e-1)" PUM1 "KIAA0099, PUMH1" ENSG00000134644 "Pumilio RNA binding family member 1" Q14671 1 30931506-31065991 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Spermatogenesis, Translation regulation" RNA-binding "Disease variant, Epilepsy, Intellectual disability, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027424, HPA027449" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 37: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 27 Cytosol Nucleoplasm "HPA027424: , HPA027449: " "unprognostic (2.86e-2)" "unprognostic (1.36e-1)" "unprognostic (1.32e-1)" "unprognostic (1.31e-1)" "unprognostic (4.47e-3)" "unprognostic (9.08e-2)" "unprognostic (3.99e-2)" "unprognostic (1.83e-2)" "unprognostic (9.95e-2)" "potential prognostic unfavorable (4.60e-4)" "validated prognostic favorable (1.07e-7)" "validated prognostic favorable (2.77e-4)" "unprognostic (4.82e-2)" "potential prognostic unfavorable (1.09e-4)" "unprognostic (2.51e-2)" "unprognostic (3.86e-1)" "unprognostic (6.30e-3)" "unprognostic (3.34e-1)" "unprognostic (1.38e-1)" "unprognostic (5.00e-3)" "unprognostic (2.51e-1)" "unprognostic (2.61e-3)" "unprognostic (3.51e-1)" "unprognostic (5.19e-2)" "unprognostic (1.81e-2)" "unprognostic (2.89e-2)" "unprognostic (5.42e-2)" "unprognostic (1.66e-1)" "unprognostic (2.48e-1)" "unprognostic (9.56e-2)" "unprognostic (1.02e-1)" PUM2 "KIAA0235, PUMH2" ENSG00000055917 "Pumilio RNA binding family member 2" Q8TB72 2 20248691-20352234 "Predicted intracellular proteins" "Translation regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030316, HPA049670" Approved Enhanced Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 7: Non-specific - Transcription" 10 Cytosol "HPA030316: , HPA049670: " "unprognostic (1.42e-2)" "unprognostic (3.99e-2)" "unprognostic (7.06e-2)" "unprognostic (3.48e-3)" "unprognostic (9.01e-2)" "unprognostic (1.24e-1)" "unprognostic (1.89e-1)" "unprognostic (1.96e-1)" "unprognostic (2.33e-3)" "unprognostic (3.51e-2)" "potential prognostic favorable (1.53e-5)" "unprognostic (1.75e-2)" "unprognostic (4.42e-2)" "unprognostic (1.43e-3)" "unprognostic (9.01e-3)" "unprognostic (7.29e-2)" "unprognostic (2.17e-2)" "unprognostic (2.02e-2)" "unprognostic (7.75e-2)" "unprognostic (9.84e-2)" "unprognostic (1.33e-2)" "unprognostic (2.14e-2)" "unprognostic (2.00e-3)" "unprognostic (4.66e-2)" "unprognostic (1.23e-2)" "unprognostic (3.49e-3)" "unprognostic (1.66e-1)" "unprognostic (3.04e-1)" "unprognostic (1.85e-1)" "unprognostic (5.68e-2)" "unprognostic (1.95e-1)" PUM3 "HA-8, hPUF-A, KIAA0020, PEN, Puf-A, PUF6, XTP5" ENSG00000080608 "Pumilio RNA binding family member 3" Q15397 9 2720469-2844095 "Predicted intracellular proteins" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 625.2;Rod photoreceptor cells: 490.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002353 Approved Supported Nucleoli NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 47: Leukemia - Hemostasis" "Cluster 79: Photoreceptor cells - Phototransduction" 82 Nucleoli "HPA002353: " "unprognostic (4.20e-2)" "unprognostic (4.32e-1)" "unprognostic (7.82e-3)" "unprognostic (1.28e-1)" "unprognostic (7.11e-2)" "unprognostic (7.01e-2)" "unprognostic (1.12e-1)" "unprognostic (3.05e-2)" "unprognostic (1.16e-1)" "unprognostic (5.42e-3)" "unprognostic (2.04e-1)" "unprognostic (4.67e-2)" "potential prognostic unfavorable (1.28e-6)" "unprognostic (4.83e-2)" "potential prognostic unfavorable (4.67e-4)" "unprognostic (4.51e-2)" "unprognostic (1.06e-1)" "unprognostic (2.78e-1)" "unprognostic (3.69e-2)" "unprognostic (3.66e-2)" "unprognostic (1.35e-2)" "potential prognostic unfavorable (6.35e-4)" "unprognostic (2.12e-2)" "unprognostic (9.45e-2)" "unprognostic (3.06e-2)" "unprognostic (2.23e-1)" "unprognostic (5.02e-2)" "unprognostic (2.05e-1)" "unprognostic (2.60e-1)" PURA "PUR-ALPHA, PUR1, PURALPHA" ENSG00000185129 "Purine rich element binding protein A" Q00577 5 140107777-140125619 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 1400000 "Cluster 32: Basophils - Transcription" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 48 "unprognostic (1.74e-2)" "unprognostic (8.38e-2)" "unprognostic (7.37e-2)" "unprognostic (4.57e-3)" "unprognostic (1.26e-1)" "unprognostic (8.52e-2)" "unprognostic (1.36e-2)" "unprognostic (1.24e-1)" "unprognostic (2.68e-1)" "potential prognostic unfavorable (5.64e-4)" "validated prognostic favorable (5.14e-10)" "validated prognostic favorable (5.26e-5)" "unprognostic (2.15e-1)" "unprognostic (1.44e-1)" "unprognostic (9.93e-2)" "unprognostic (2.27e-2)" "unprognostic (2.55e-1)" "unprognostic (8.68e-2)" "unprognostic (1.81e-1)" "unprognostic (1.24e-1)" "potential prognostic unfavorable (3.59e-4)" "unprognostic (1.42e-1)" "unprognostic (9.18e-2)" "unprognostic (2.96e-1)" "unprognostic (9.28e-2)" "unprognostic (8.57e-3)" "unprognostic (3.16e-1)" "unprognostic (3.01e-2)" "unprognostic (2.94e-1)" "unprognostic (1.97e-1)" "unprognostic (1.44e-1)" PURB PURBETA ENSG00000146676 "Purine rich element binding protein B" Q96QR8 7 44876299-44885530 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048766 Supported Nucleoplasm NA NA 110000 "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 31: Non-specific - Transcription" "Cluster 67: Non-specific - Unknown function" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 36 Nucleoplasm "HPA048766: " "unprognostic (1.38e-1)" "unprognostic (1.25e-1)" "unprognostic (4.47e-1)" "unprognostic (1.68e-2)" "unprognostic (1.29e-2)" "unprognostic (1.86e-2)" "unprognostic (7.48e-2)" "unprognostic (2.88e-2)" "unprognostic (3.71e-1)" "potential prognostic unfavorable (1.45e-4)" "potential prognostic favorable (3.38e-4)" "unprognostic (2.32e-3)" "unprognostic (2.44e-1)" "unprognostic (7.40e-3)" "unprognostic (1.79e-1)" "unprognostic (8.24e-3)" "unprognostic (1.90e-1)" "unprognostic (1.43e-1)" "unprognostic (1.99e-2)" "unprognostic (1.45e-2)" "unprognostic (2.24e-1)" "unprognostic (1.58e-1)" "unprognostic (3.66e-2)" "unprognostic (1.07e-1)" "unprognostic (4.35e-2)" "unprognostic (1.32e-1)" "unprognostic (1.74e-1)" "unprognostic (1.69e-2)" "unprognostic (2.41e-1)" "unprognostic (3.61e-2)" "unprognostic (1.58e-1)" PURG "PURG-A, PURG-B" ENSG00000172733 "Purine rich element binding protein G" Q9UJV8 8 30995802-31033715 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 11.2;retina: 4.0" "Cell type enhanced" "Detected in many" "Astrocytes: 89.1;Bergmann glia: 69.8;Brain excitatory neurons: 79.9;Brain inhibitory neurons: 80.7;Ependymal cells: 101.2;Lactotrophs: 79.3;Late spermatids: 33.2;Oligodendrocyte progenitor cells: 86.0;Oligodendrocytes: 42.0;Other brain neurons: 66.3;Pituicytes/FSCs: 75.2;Retinal amacrine cells: 49.0;Retinal ganglion cells: 46.4;Retinal horizontal cells: 52.1" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Glioblastoma Multiforme (TCGA): 4.8;Kidney Chromophobe (TCGA): 1.8;Kidney Renal Papillary Cell Carcinoma (TCGA): 1.5;Testicular Germ Cell Tumor (TCGA): 1.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 6.5" "Colon - Enteric glia cells, Prostate - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047746 Enhanced Approved "Nucleoplasm,Nucleoli,Plasma membrane,Cytokinetic bridge,Centrosome,Basal body" Yes NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 2: Neurons - Nucleosome" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 64 Nucleoplasm "Nucleoli, Plasma membrane, Cytokinetic bridge, Centrosome, Basal body" "HPA047746: " "unprognostic (1.30e-1)" "unprognostic (4.42e-2)" "unprognostic (2.42e-3)" "unprognostic (6.29e-2)" "unprognostic (1.38e-1)" "unprognostic (1.29e-1)" PUS1 MLASA1 ENSG00000177192 "Pseudouridine synthase 1" Q9Y606 12 131929200-131945896 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "mRNA processing, mRNA splicing, tRNA processing" Isomerase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051636, HPA057593" Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 49: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 5 "Nucleoplasm, Mitochondria" "HPA051636: , HPA057593: " "unprognostic (4.53e-3)" "unprognostic (1.76e-1)" "unprognostic (1.52e-1)" "unprognostic (4.51e-2)" "unprognostic (1.31e-1)" "unprognostic (1.16e-1)" "unprognostic (3.02e-1)" "potential prognostic favorable (2.34e-4)" "unprognostic (2.60e-2)" "unprognostic (1.36e-2)" "potential prognostic unfavorable (5.74e-4)" "unprognostic (8.84e-3)" "unprognostic (2.45e-3)" "validated prognostic unfavorable (2.35e-8)" "validated prognostic unfavorable (7.52e-4)" "unprognostic (1.14e-2)" "unprognostic (2.11e-3)" "unprognostic (2.45e-1)" "unprognostic (1.97e-2)" "unprognostic (1.29e-1)" "unprognostic (9.59e-2)" "unprognostic (1.65e-2)" "unprognostic (5.47e-2)" "unprognostic (5.51e-2)" "unprognostic (5.39e-3)" "unprognostic (6.93e-3)" "unprognostic (4.40e-2)" "unprognostic (2.15e-2)" "unprognostic (1.60e-1)" "unprognostic (1.10e-1)" "unprognostic (2.40e-1)" PUS10 "CCDC139, FLJ32312" ENSG00000162927 "Pseudouridine synthase 10" Q3MIT2 2 60940222-61018259 "Enzymes, Predicted intracellular proteins" "tRNA processing" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 95.7;Epicardial cells: 295.6;Myonuclei: 93.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044736, HPA049582" Approved Approved "Nucleoplasm,Nuclear bodies,Mitochondria" No No "Cluster 14: Non-specific - Unknown function" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 55: Non-specific - Transcription" "Cluster 55: Lymphoma - Immune response" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 8 "Nucleoplasm, Nuclear bodies, Mitochondria" "HPA044736: , HPA049582: " "unprognostic (1.93e-1)" "unprognostic (6.03e-2)" "unprognostic (1.64e-1)" "unprognostic (1.10e-3)" "unprognostic (3.46e-1)" "unprognostic (8.51e-3)" "unprognostic (6.65e-2)" "unprognostic (1.24e-1)" "unprognostic (4.98e-2)" "unprognostic (4.61e-2)" "unprognostic (2.63e-1)" "unprognostic (6.15e-2)" "unprognostic (1.31e-1)" "unprognostic (6.21e-2)" "unprognostic (7.11e-3)" "unprognostic (1.19e-3)" "unprognostic (2.72e-1)" "unprognostic (1.95e-1)" "unprognostic (1.10e-1)" "unprognostic (1.68e-1)" "potential prognostic unfavorable (5.05e-4)" "unprognostic (8.25e-2)" "unprognostic (7.22e-2)" "unprognostic (8.45e-2)" "unprognostic (4.00e-2)" "unprognostic (4.26e-2)" "unprognostic (1.00e-2)" "unprognostic (1.82e-1)" "unprognostic (1.36e-1)" "unprognostic (2.27e-1)" "unprognostic (1.85e-1)" PUS3 "DEG1, FKSG32" ENSG00000110060 "Pseudouridine synthase 3" Q9BZE2 11 125893485-125903221 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "tRNA processing" Isomerase "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 35.8;Pancreatic acinar cells: 33.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038040, HPA063802" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 31: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" Nucleoplasm Cytosol "HPA038040: , HPA063802: " "unprognostic (6.82e-2)" "unprognostic (1.15e-2)" "potential prognostic favorable (2.56e-4)" "unprognostic (1.86e-2)" "unprognostic (1.12e-1)" "unprognostic (2.49e-1)" "unprognostic (8.01e-2)" "unprognostic (1.29e-3)" "unprognostic (1.15e-2)" "unprognostic (9.53e-2)" "unprognostic (6.71e-3)" "unprognostic (5.93e-2)" "unprognostic (1.48e-1)" "unprognostic (8.30e-2)" "unprognostic (5.29e-3)" "unprognostic (1.04e-1)" "unprognostic (9.94e-3)" "unprognostic (1.03e-2)" "unprognostic (6.71e-2)" "unprognostic (6.53e-2)" "unprognostic (3.07e-3)" "unprognostic (5.23e-3)" "unprognostic (1.78e-1)" "unprognostic (8.37e-3)" "unprognostic (2.29e-2)" "unprognostic (2.07e-3)" "unprognostic (1.52e-2)" "unprognostic (2.34e-1)" "unprognostic (1.64e-1)" "unprognostic (1.51e-1)" "unprognostic (8.50e-3)" PUS7 FLJ20485 ENSG00000091127 "Pseudouridine synthase 7" Q96PZ0 7 105439661-105522271 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing, tRNA processing" Isomerase "Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 102.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024116 Approved Approved Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 37: Neurons - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 42 Nucleoplasm "HPA024116: " "unprognostic (1.78e-1)" "unprognostic (1.24e-1)" "unprognostic (2.21e-1)" "unprognostic (4.79e-2)" "unprognostic (1.34e-1)" "unprognostic (1.94e-1)" "unprognostic (1.74e-1)" "unprognostic (4.54e-1)" "unprognostic (1.43e-1)" "unprognostic (7.52e-3)" "unprognostic (1.58e-1)" "unprognostic (2.50e-2)" "unprognostic (8.55e-3)" "validated prognostic unfavorable (1.70e-6)" "validated prognostic unfavorable (6.18e-6)" "unprognostic (6.35e-3)" "unprognostic (5.94e-3)" "unprognostic (2.51e-2)" "unprognostic (2.24e-1)" "unprognostic (6.06e-2)" "unprognostic (3.45e-1)" "unprognostic (7.12e-3)" "unprognostic (1.11e-1)" "unprognostic (1.72e-2)" "unprognostic (5.18e-2)" "unprognostic (1.41e-2)" "unprognostic (1.67e-3)" "unprognostic (2.52e-1)" "unprognostic (3.58e-2)" "potential prognostic unfavorable (5.76e-4)" "unprognostic (6.57e-2)" PUS7L DKFZP434G1415 ENSG00000129317 "Pseudouridine synthase 7 like" Q9H0K6 12 43718992-43758793 "Predicted intracellular proteins" "mRNA processing" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056203, HPA058750" Uncertain Approved "Nucleoli,Nuclear speckles" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 42: Retina - Visual perception" "Cluster 9: Non-specific - Receptor signaling" "Cluster 38: Non-specific - Transcription" "Cluster 109: Neurons - Neuronal signaling" 3 "Nuclear speckles" Nucleoli "HPA056203: , HPA058750: " "unprognostic (1.02e-2)" "unprognostic (3.17e-2)" "unprognostic (2.99e-1)" "unprognostic (5.45e-2)" "unprognostic (1.63e-1)" "unprognostic (3.81e-2)" "unprognostic (5.13e-2)" "unprognostic (2.41e-1)" "unprognostic (1.68e-1)" "potential prognostic unfavorable (2.31e-4)" "unprognostic (6.12e-3)" "unprognostic (4.01e-1)" "unprognostic (3.51e-2)" "potential prognostic unfavorable (7.68e-4)" "unprognostic (3.57e-1)" "unprognostic (4.14e-2)" "unprognostic (1.99e-2)" "potential prognostic favorable (4.49e-4)" "unprognostic (3.15e-2)" "unprognostic (6.12e-2)" "unprognostic (2.43e-3)" "unprognostic (1.95e-2)" "unprognostic (1.60e-3)" "unprognostic (3.74e-2)" "unprognostic (6.03e-3)" "unprognostic (5.66e-2)" "unprognostic (2.00e-2)" "unprognostic (3.65e-1)" "unprognostic (5.44e-2)" "unprognostic (1.87e-2)" "unprognostic (1.60e-1)" PUSL1 FLJ90811 ENSG00000169972 "Pseudouridine synthase like 1" Q8N0Z8 1 1308597-1311677 "Predicted intracellular proteins" "tRNA processing" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Esophageal apical cells: 275.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032057, HPA039999" Uncertain Enhanced Vesicles NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 84: Apical squamous epithelium - Cornification" 4 Vesicles "HPA032057: , HPA039999: " "unprognostic (3.94e-3)" "unprognostic (1.86e-2)" "unprognostic (1.14e-1)" "unprognostic (9.18e-3)" "unprognostic (1.11e-1)" "unprognostic (3.35e-2)" "unprognostic (7.79e-2)" "unprognostic (1.93e-1)" "unprognostic (3.80e-1)" "unprognostic (7.63e-3)" "potential prognostic unfavorable (4.69e-7)" "unprognostic (9.87e-3)" "unprognostic (2.63e-1)" "validated prognostic unfavorable (2.07e-4)" "validated prognostic unfavorable (3.23e-6)" "unprognostic (9.45e-2)" "unprognostic (1.93e-1)" "unprognostic (4.15e-1)" "unprognostic (2.85e-1)" "unprognostic (2.36e-1)" "unprognostic (5.02e-2)" "unprognostic (6.62e-2)" "unprognostic (7.69e-2)" "unprognostic (2.40e-1)" "unprognostic (3.25e-1)" "unprognostic (1.75e-2)" "unprognostic (5.61e-2)" "unprognostic (2.04e-1)" "unprognostic (1.81e-1)" "unprognostic (3.15e-1)" "unprognostic (4.48e-2)" PVALB D22S749 ENSG00000100362 Parvalbumin P20472 22 36800684-36819479 "Predicted intracellular proteins" "Muscle protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 639.2;parathyroid gland: 1992.9;retina: 346.2" "Cell type enriched" "Detected in some" 6 "Retinal horizontal cells: 575.0" "Group enriched" "Detected in many" 4 "cerebellar inhibitory: 402.3;thalamic excitatory: 121.6" "Cancer enriched" "Detected in many" 32 "Kidney Chromophobe (TCGA): 1671.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "neutrophil: 4.6" "Lineage enriched" "Detected in single" 5 "granulocytes: 4.6" "Group enriched" "Detected in some" 9 "breast cancer: 16.4;Myeloma: 56.0" "Liver - Sinusoid Endothelial cells" "Region enriched" "Detected in all" 5 "cerebellum: 2120.2" "Low region specificity" "Detected in all" "CAB002515, HPA048536" Enhanced Approved "Nucleoplasm,Nucleoli,Cell Junctions" No NA "Cluster 4: Neutrophils - Degranulation" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 109: Neurons - Neuronal signaling" Nucleoplasm "Nucleoli, Cell Junctions" "CAB002515: , HPA048536: " "unprognostic (3.87e-2)" "unprognostic (1.31e-2)" "potential prognostic unfavorable (2.70e-4)" "unprognostic (2.52e-2)" "unprognostic (4.22e-1)" "unprognostic (3.47e-2)" "unprognostic (9.15e-2)" "unprognostic (1.99e-2)" "unprognostic (1.27e-2)" "unprognostic (5.23e-2)" "unprognostic (2.06e-1)" "unprognostic (5.92e-3)" "unprognostic (5.78e-2)" "unprognostic (2.07e-1)" "unprognostic (2.28e-2)" "unprognostic (2.25e-1)" "unprognostic (4.54e-3)" "unprognostic (1.41e-2)" "unprognostic (1.28e-2)" "unprognostic (1.57e-1)" PVALEF AATK-AS1 ENSG00000225180 "Parvalbumin like EF-hand containing" A0A1B0GWK0 17 81165507-81183166 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 7.8;Brain inhibitory neurons: 7.2;Corticotrophs: 5.5;Gonadotrophs: 9.5;Lactotrophs: 16.0;Müller glia: 7.5;Oligodendrocytes: 8.0;Other brain neurons: 5.5;Retinal amacrine cells: 7.5;Retinal bipolar cells: 10.1;Retinal horizontal cells: 6.0;Somatotrophs: 17.6" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 48: Non-specific - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" PVR "CD155, HVED, Necl-5, NECL5, PVS, Tage4" ENSG00000073008 "PVR cell adhesion molecule" P15151 19 44643798-44666162 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 67.5;Epicardial cells: 29.6;Podocytes: 48.0;Salivary myoepithelial cells: 36.8;Tuft cells: 34.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 4.4;intermediate monocyte: 4.4;myeloid DC: 3.6;neutrophil: 1.4;non-classical monocyte: 5.1" "Group enriched" "Detected in many" 4 "dendritic cells: 3.6;granulocytes: 1.4;monocytes: 5.1" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012568, HPA064739" Approved Supported "Nucleoplasm,Vesicles,Plasma membrane" "Secreted - unknown location" Receptor NA NA 160000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 70: Non-specific - Protein processing" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 58 "Nucleoplasm, Vesicles, Plasma membrane" "HPA012568: , HPA064739: " "unprognostic (2.97e-2)" "unprognostic (2.42e-3)" "unprognostic (1.30e-1)" "potential prognostic unfavorable (1.01e-4)" "unprognostic (6.93e-2)" "unprognostic (3.70e-2)" "unprognostic (1.51e-1)" "unprognostic (1.34e-1)" "unprognostic (1.77e-3)" "unprognostic (4.32e-1)" "unprognostic (4.41e-2)" "unprognostic (9.65e-2)" "unprognostic (4.48e-2)" "unprognostic (1.40e-2)" "unprognostic (4.44e-2)" "potential prognostic unfavorable (5.78e-6)" "unprognostic (1.01e-1)" "unprognostic (1.39e-2)" "unprognostic (1.09e-1)" "unprognostic (4.05e-2)" "unprognostic (1.29e-1)" "unprognostic (8.75e-3)" "unprognostic (2.53e-3)" "unprognostic (7.85e-2)" "unprognostic (1.38e-2)" "unprognostic (5.42e-2)" "unprognostic (4.78e-2)" "unprognostic (1.60e-1)" "unprognostic (6.76e-2)" "unprognostic (3.53e-3)" "unprognostic (1.74e-1)" PVRIG "C7orf15, CD112R, MGC2463" ENSG00000213413 "PVR related immunoglobulin domain containing" Q6DKI7 7 100218241-100221490 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "lymphoid tissue: 44.5" "Cell type enhanced" "Detected in some" "NK-cells: 1.4;T-cells: 1.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 33 "gdT-cell: 297.4;MAIT T-cell: 352.7;memory B-cell: 174.9;memory CD4 T-cell: 193.5;memory CD8 T-cell: 293.8;naive B-cell: 155.3;naive CD4 T-cell: 213.7;naive CD8 T-cell: 212.0;NK-cell: 335.0;T-reg: 171.9" "Group enriched" "Detected in all" 39 "B-cells: 174.9;NK-cells: 335.0;T-cells: 352.7" "Group enriched" "Detected in some" 9 "Leukemia: 13.5;lymphoma: 36.5" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA047497 Uncertain NA NA "Cluster 24: Non-specific - Transcription" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 6: Non-specific - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 7 "HPA047497: " "unprognostic (8.75e-2)" "potential prognostic favorable (7.11e-5)" "unprognostic (3.54e-2)" "unprognostic (5.97e-3)" "unprognostic (5.77e-2)" "potential prognostic favorable (3.33e-4)" "unprognostic (1.78e-1)" "unprognostic (1.63e-1)" "unprognostic (7.43e-2)" "unprognostic (2.11e-2)" "unprognostic (1.49e-1)" "unprognostic (7.30e-2)" "unprognostic (1.66e-3)" "unprognostic (8.98e-3)" "unprognostic (1.99e-1)" "unprognostic (9.41e-3)" "unprognostic (2.19e-1)" PWP1 IEF-SSP-9502 ENSG00000136045 "PWP1 homolog, endonuclein" Q13610 12 107685799-107713162 "Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038708 Approved "Nucleoli rim,Golgi apparatus" Yes No "Cluster 14: Non-specific - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 19 "Nucleoli rim" "Golgi apparatus" "HPA038708: " "unprognostic (1.94e-2)" "unprognostic (1.02e-2)" "unprognostic (4.61e-2)" "unprognostic (7.13e-2)" "unprognostic (7.06e-2)" "unprognostic (2.50e-1)" "unprognostic (1.90e-1)" "unprognostic (3.81e-1)" "unprognostic (1.12e-3)" "unprognostic (1.49e-2)" "potential prognostic favorable (6.11e-5)" "unprognostic (1.27e-1)" "unprognostic (1.45e-3)" "validated prognostic unfavorable (5.29e-6)" "validated prognostic unfavorable (2.52e-4)" "potential prognostic unfavorable (2.42e-4)" "unprognostic (1.74e-3)" "unprognostic (4.34e-2)" "unprognostic (1.98e-2)" "unprognostic (1.32e-1)" "unprognostic (2.14e-2)" "unprognostic (7.90e-3)" "unprognostic (4.78e-3)" "unprognostic (2.62e-1)" "unprognostic (3.88e-3)" "unprognostic (5.66e-2)" "unprognostic (7.17e-2)" "unprognostic (1.18e-1)" "unprognostic (1.64e-1)" "unprognostic (1.89e-1)" "unprognostic (2.74e-1)" PWP2 "EHOC-17, PWP2H, UTP1" ENSG00000241945 "PWP2 small subunit processome component" Q15269 21 44107373-44131181 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 4.9;Enteric stem cells: 4.9;Goblet cells: 4.1;Kupffer cells: 9.2;Megakaryocyte progenitors: 5.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024573 Uncertain Supported Nucleoli,Cytosol NA NA 6800 "Cluster 24: Non-specific - Transcription" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 22 Nucleoli Cytosol "HPA024573: " "unprognostic (5.44e-2)" "unprognostic (1.45e-1)" "unprognostic (5.03e-2)" "unprognostic (2.10e-1)" "unprognostic (1.41e-1)" "unprognostic (8.89e-2)" "unprognostic (2.29e-1)" "unprognostic (1.77e-3)" "unprognostic (1.87e-1)" "unprognostic (3.39e-1)" "unprognostic (2.39e-1)" "unprognostic (1.23e-1)" "unprognostic (3.71e-2)" "unprognostic (3.41e-1)" "unprognostic (2.67e-2)" "unprognostic (1.98e-1)" "unprognostic (3.42e-1)" "unprognostic (3.09e-1)" "unprognostic (1.47e-1)" "unprognostic (9.49e-3)" "unprognostic (2.51e-1)" "unprognostic (3.41e-2)" "unprognostic (8.71e-3)" "unprognostic (2.04e-1)" "unprognostic (2.62e-1)" "unprognostic (1.73e-1)" "unprognostic (5.26e-2)" "potential prognostic unfavorable (4.01e-4)" "unprognostic (7.80e-2)" "unprognostic (1.14e-2)" "unprognostic (6.05e-2)" PWWP2A KIAA1935 ENSG00000170234 "PWWP domain containing 2A" Q96N64 5 160061801-160119450 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046733, HPA058233" Supported "Nucleoplasm,Focal adhesion sites" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 19 Nucleoplasm "Focal adhesion sites" "HPA046733: , HPA058233: " "unprognostic (1.45e-3)" "unprognostic (1.69e-2)" "unprognostic (5.45e-2)" "unprognostic (1.26e-1)" "unprognostic (8.59e-2)" "unprognostic (1.25e-3)" "unprognostic (5.30e-2)" "unprognostic (3.93e-1)" "unprognostic (5.38e-2)" "unprognostic (2.84e-3)" "unprognostic (1.57e-3)" "unprognostic (2.51e-2)" "unprognostic (6.44e-2)" "unprognostic (2.85e-3)" "unprognostic (2.06e-2)" "unprognostic (2.58e-1)" "unprognostic (1.45e-1)" "unprognostic (6.45e-2)" "unprognostic (1.86e-1)" "unprognostic (2.79e-2)" "unprognostic (3.20e-2)" "unprognostic (7.14e-2)" "unprognostic (4.00e-2)" "unprognostic (1.82e-2)" "unprognostic (3.86e-2)" "unprognostic (3.87e-3)" "unprognostic (1.16e-2)" "unprognostic (1.47e-1)" "unprognostic (5.48e-2)" "unprognostic (4.05e-2)" "unprognostic (2.92e-1)" PWWP2B "bA432J24.1, FLJ46823, PWWP2" ENSG00000171813 "PWWP domain containing 2B" Q6NUJ5 10 132397168-132417859 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 123.5;Extravillous trophoblasts: 61.2;Late spermatids: 117.3;Respiratory ciliated cells: 61.4;Syncytiotrophoblasts: 66.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038056, HPA076698, HPA078118" Approved Enhanced Nucleoplasm NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 33: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." 6 Nucleoplasm "HPA038056: , HPA076698: , HPA078118: " "unprognostic (2.64e-2)" "unprognostic (1.30e-1)" "unprognostic (3.58e-1)" "unprognostic (2.53e-2)" "unprognostic (1.15e-2)" "unprognostic (4.63e-1)" "unprognostic (2.38e-1)" "potential prognostic favorable (5.89e-5)" "unprognostic (7.13e-2)" "unprognostic (1.56e-3)" "unprognostic (5.04e-2)" "unprognostic (2.26e-2)" "unprognostic (7.19e-2)" "unprognostic (4.55e-3)" "unprognostic (1.78e-2)" "unprognostic (1.79e-1)" "unprognostic (4.35e-2)" "unprognostic (7.49e-2)" "unprognostic (1.75e-1)" "unprognostic (8.20e-2)" "unprognostic (5.23e-2)" "unprognostic (3.79e-2)" "unprognostic (3.05e-1)" "unprognostic (8.10e-2)" "unprognostic (2.18e-1)" "unprognostic (1.14e-1)" "unprognostic (2.89e-1)" "unprognostic (7.37e-2)" "unprognostic (1.82e-1)" "unprognostic (1.04e-1)" "potential prognostic favorable (6.46e-4)" PWWP3A "EXPAND1, MUM-1, MUM1" ENSG00000160953 "PWWP domain containing 3A, DNA repair factor" Q2TAK8 19 1354711-1378431 "Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 228.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048063, HPA054491" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 65: Brain - Transcription" "Cluster 19: Astrocytes - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 1 "Nucleoplasm, Cytosol" "HPA048063: , HPA054491: " "unprognostic (6.62e-3)" "unprognostic (1.21e-1)" "unprognostic (1.48e-1)" "unprognostic (1.93e-1)" "unprognostic (2.65e-1)" "unprognostic (1.63e-1)" "unprognostic (1.05e-3)" "unprognostic (4.37e-2)" "unprognostic (9.66e-2)" "unprognostic (3.40e-3)" "unprognostic (4.19e-2)" "unprognostic (3.66e-2)" "unprognostic (4.57e-2)" "unprognostic (1.98e-2)" "unprognostic (2.39e-1)" "unprognostic (2.04e-1)" "unprognostic (2.58e-2)" "unprognostic (1.87e-2)" "unprognostic (5.28e-1)" "potential prognostic favorable (1.13e-5)" "unprognostic (1.32e-2)" "unprognostic (6.57e-2)" "unprognostic (2.08e-1)" "unprognostic (2.77e-2)" "unprognostic (8.65e-2)" "unprognostic (6.45e-2)" "unprognostic (2.96e-1)" "unprognostic (1.03e-1)" "unprognostic (2.61e-1)" PWWP3B "FLJ33516, MUM1L1" ENSG00000157502 "PWWP domain containing 3B" Q5H9M0 X 106168305-106208956 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 103.6" "Cell type enhanced" "Detected in many" "Cholangiocytes: 52.4;Decidual stromal cells: 61.0;Endometrial stromal cells: 68.2;Epicardial cells: 72.8;Gonadotrophs: 78.3;Leydig cells: 113.4;Mesothelial cells: 47.7;Ovarian stromal cells: 292.4;Peritubular myoid cells: 127.9;Sertoli cells: 265.2" "Cell type enhanced" "Detected in many" "hippocampal CA4: 75.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Pituitary gland - Corticotropes, Skeletal muscle - Skeletal myocytes, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000168, HPA020464" Enhanced NA NA "Cluster 75: Ovary - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 27: Breast cancer - Unknown function" "Cluster 94: Gonadal somatic cells - Mixed function" "HPA000168: , HPA020464: " "unprognostic (7.59e-2)" "unprognostic (2.48e-1)" "unprognostic (4.40e-2)" "unprognostic (6.27e-2)" "potential prognostic favorable (5.12e-5)" "unprognostic (3.07e-2)" "unprognostic (1.39e-2)" "unprognostic (1.84e-1)" "unprognostic (1.63e-1)" "unprognostic (3.18e-1)" "unprognostic (6.49e-2)" "unprognostic (5.05e-2)" "unprognostic (4.88e-3)" "unprognostic (1.99e-1)" "potential prognostic unfavorable (1.51e-4)" PWWP4 ENSG00000278803 "PWWP domain containing 4" X 153266152-153279145 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 24: Non-specific - Unknown function" PXDC1 C6orf145 ENSG00000168994 "PX domain containing 1" Q5TGL8 6 3722614-3751713 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 213.5;liver: 184.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 118.0;Extravillous trophoblasts: 194.3;Hepatocytes: 84.2" "Cell type enhanced" "Detected in many" "endothelial cell: 67.6;vascular associated smooth muscle cell: 48.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.2" "Lineage enhanced" "Detected in single" "B-cells: 1.2" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Endothelial cells, Prostate - Smooth muscle cells, Skeletal muscle - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA019246 Approved "Plasma membrane" NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 8: Immune cells - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 3 "Plasma membrane" "HPA019246: " "unprognostic (1.15e-1)" "unprognostic (2.09e-1)" "unprognostic (8.41e-2)" "unprognostic (5.92e-3)" "unprognostic (2.78e-1)" "unprognostic (2.54e-1)" "unprognostic (4.01e-2)" "unprognostic (1.28e-2)" "unprognostic (9.72e-2)" "unprognostic (2.14e-3)" "unprognostic (5.21e-3)" "potential prognostic favorable (4.61e-4)" "unprognostic (2.37e-1)" "unprognostic (5.03e-2)" "unprognostic (6.96e-2)" "unprognostic (6.31e-2)" "unprognostic (4.78e-2)" "unprognostic (1.24e-1)" "unprognostic (4.87e-2)" "unprognostic (1.46e-1)" "unprognostic (6.56e-2)" "unprognostic (2.37e-1)" "unprognostic (5.46e-2)" "unprognostic (7.24e-2)" "unprognostic (2.26e-1)" "potential prognostic unfavorable (9.21e-4)" "unprognostic (9.94e-2)" "unprognostic (2.66e-1)" "potential prognostic unfavorable (6.54e-4)" PXDN "D2S448, D2S448E, KIAA0230, MG50, PRG2, PXN" ENSG00000130508 Peroxidasin Q92626 2 1631887-1744852 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Hydrogen peroxide" "Oxidoreductase, Peroxidase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 292.4;Choroid plexus epithelial cells: 149.1;Endometrial stromal cells: 159.5;Hepatic stellate cells: 174.3;Myosatellite cells: 264.3;Oligodendrocyte progenitor cells: 96.1" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 128.9;oligodendrocyte precursor cell: 103.7" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "choroid plexus: 51.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 181.8" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Fibroblasts, Breast - Adipocytes (Breast), Lung - Endothelial cells, Prostate - Smooth muscle cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA012375 Approved "Secreted to extracellular matrix" Enzyme NA NA 6000000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 89: Adipocytes - Lipid metabolism" 9 "HPA012375: " "unprognostic (1.06e-1)" "unprognostic (5.48e-2)" "unprognostic (2.11e-1)" "potential prognostic unfavorable (1.95e-4)" "unprognostic (2.41e-2)" "unprognostic (2.04e-2)" "unprognostic (2.28e-2)" "unprognostic (4.80e-2)" "unprognostic (1.57e-1)" "unprognostic (6.11e-3)" "unprognostic (2.57e-1)" "unprognostic (1.89e-2)" "unprognostic (2.08e-1)" "unprognostic (3.24e-2)" "unprognostic (1.39e-1)" "unprognostic (1.17e-2)" "unprognostic (2.63e-3)" "unprognostic (1.09e-1)" "unprognostic (1.37e-1)" "potential prognostic unfavorable (6.19e-4)" "unprognostic (5.96e-2)" "unprognostic (4.63e-2)" "unprognostic (1.29e-1)" "unprognostic (1.20e-1)" "unprognostic (3.04e-1)" "unprognostic (2.31e-1)" "unprognostic (5.78e-3)" "unprognostic (1.78e-3)" "unprognostic (2.32e-1)" "unprognostic (5.92e-3)" "unprognostic (3.41e-2)" PXDNL "FLJ25471, PMR1" ENSG00000147485 "Peroxidasin like" A1KZ92 8 51319577-51809445 "Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "heart muscle: 43.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 902.6;Fibro-adipogenic progenitors: 179.2;Late primary spermatocytes: 134.9;Müller glia: 231.9;Myonuclei: 127.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Heart muscle - Cardiomyocytes, Kidney - Ascending Loop of Henle cells, Testis - Early spermatids" HPA007919 Approved Nucleoplasm,Cytosol "Intracellular and membrane" Enzyme NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" "Nucleoplasm, Cytosol" "HPA007919: " "potential prognostic unfavorable (1.92e-5)" "unprognostic (2.39e-1)" "unprognostic (2.46e-1)" "unprognostic (3.12e-1)" "unprognostic (6.48e-2)" "unprognostic (5.72e-2)" "unprognostic (7.69e-3)" "unprognostic (8.43e-2)" PXK "FLJ20335, Slob" ENSG00000168297 "PX domain containing serine/threonine kinase like" Q7Z7A4 3 58332880-58426127 "Enzymes, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 121.9" "Cell type enhanced" "Detected in many" "Neutrophil progenitors: 256.0;Neutrophils: 568.8;Oligodendrocytes: 824.6;Renal collecting duct intercalated cells: 353.1" "Group enriched" "Detected in all" 4 "committed oligodendrocyte precursor: 356.6;oligodendrocyte: 1093.6" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 100.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Leukemia: 73.5" "Adrenal gland - Adrenal cortex cells, Kidney - Fibroblasts, Lung - Fibroblasts_1, Prostate - Fibroblasts, Skin - Endothelial cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024068 Supported Supported "Plasma membrane,Centriolar satellite,Cytosol" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 80: Oligodendrocytes - Myelination" 3 Cytosol "Plasma membrane, Centriolar satellite" "HPA024068: " "unprognostic (6.49e-2)" "unprognostic (1.80e-2)" "unprognostic (1.92e-2)" "unprognostic (1.54e-1)" "unprognostic (5.08e-2)" "unprognostic (2.17e-1)" "unprognostic (1.30e-1)" "unprognostic (4.36e-2)" "unprognostic (7.54e-3)" "unprognostic (9.41e-3)" "unprognostic (2.96e-2)" "unprognostic (8.40e-2)" "unprognostic (1.21e-1)" "unprognostic (5.36e-3)" "unprognostic (6.04e-2)" "unprognostic (1.46e-3)" "unprognostic (1.70e-2)" "unprognostic (3.96e-1)" "unprognostic (2.56e-1)" "unprognostic (4.33e-2)" "unprognostic (2.00e-2)" "unprognostic (1.05e-1)" "unprognostic (3.00e-1)" "unprognostic (1.45e-1)" "unprognostic (1.28e-1)" "unprognostic (8.97e-3)" "unprognostic (4.54e-2)" "unprognostic (1.01e-1)" "unprognostic (6.93e-2)" "unprognostic (3.06e-2)" "unprognostic (1.62e-1)" PXMP2 "MPV17L3, PMP22" ENSG00000176894 "Peroxisomal membrane protein 2" Q9NR77 12 132687587-132704985 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 294.8" "Group enriched" "Detected in many" 4 "Gastric chief cells: 40.4;Hepatocytes: 111.5;Parietal cells: 130.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 23: Choroid plexus - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 97: Non-specific - Cellular respiration" 8 "unprognostic (1.29e-1)" "unprognostic (1.73e-2)" "unprognostic (4.10e-2)" "unprognostic (2.17e-3)" "unprognostic (6.53e-2)" "unprognostic (2.16e-1)" "unprognostic (1.10e-1)" "unprognostic (1.49e-1)" "unprognostic (1.13e-3)" "unprognostic (2.46e-1)" "potential prognostic favorable (1.87e-7)" "unprognostic (2.92e-2)" "unprognostic (4.16e-3)" "unprognostic (9.93e-3)" "unprognostic (3.99e-1)" "unprognostic (1.34e-1)" "unprognostic (4.77e-3)" "unprognostic (9.93e-2)" "unprognostic (1.43e-2)" "unprognostic (9.79e-2)" "unprognostic (2.89e-2)" "unprognostic (2.69e-1)" "unprognostic (3.21e-2)" "unprognostic (1.78e-1)" "unprognostic (2.36e-3)" "unprognostic (5.24e-2)" "unprognostic (8.24e-3)" "unprognostic (6.37e-2)" "unprognostic (8.30e-2)" "unprognostic (2.16e-1)" "unprognostic (1.67e-1)" PXMP4 PMP24 ENSG00000101417 "Peroxisomal membrane protein 4" Q9Y6I8 20 33702758-33720319 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 98.7;Late spermatids: 59.3;Transitional alveolar cells: 54.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Skin - Sebaceous gland cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050077 Approved Approved "Nucleoli fibrillar center,Peroxisomes" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 34: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 81: Alveolar cells - Lung function" 1 Peroxisomes "Nucleoli fibrillar center" "HPA050077: " "potential prognostic favorable (4.51e-4)" "unprognostic (1.56e-2)" "unprognostic (5.28e-1)" "unprognostic (1.56e-1)" "unprognostic (2.66e-1)" "unprognostic (1.74e-1)" "unprognostic (2.47e-1)" "unprognostic (2.53e-2)" "unprognostic (6.17e-2)" "unprognostic (1.84e-2)" "potential prognostic favorable (2.10e-5)" "unprognostic (3.56e-1)" "potential prognostic favorable (5.92e-4)" "unprognostic (9.16e-2)" "unprognostic (5.30e-2)" "unprognostic (4.17e-3)" "unprognostic (1.56e-1)" "unprognostic (1.80e-1)" "unprognostic (2.99e-1)" "unprognostic (3.07e-1)" "unprognostic (8.55e-3)" "unprognostic (1.74e-1)" "unprognostic (3.45e-1)" "unprognostic (3.68e-2)" "unprognostic (7.45e-3)" "unprognostic (2.07e-1)" "unprognostic (3.43e-1)" "unprognostic (1.31e-1)" "unprognostic (2.01e-1)" "unprognostic (3.26e-1)" "unprognostic (8.25e-2)" PXN ENSG00000089159 Paxillin P49023 12 120210439-120265771 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 317.6;Neutrophils: 539.4" "Cell type enhanced" "Detected in all" "endothelial cell: 160.0;leukocyte: 119.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 170.2" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Liver - Vascular endothelial cells, Pancreas - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003841, HPA051309" Supported Enhanced "Focal adhesion sites,Centrosome,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 19: Astrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 24: Neutrophils - Innate immunity signal integration" 89 "Focal adhesion sites" "Centrosome, Cytosol" "CAB003841: , HPA051309: " "unprognostic (7.83e-2)" "unprognostic (4.15e-2)" "unprognostic (2.62e-1)" "unprognostic (1.26e-3)" "unprognostic (6.41e-2)" "unprognostic (2.22e-1)" "unprognostic (2.45e-3)" "unprognostic (6.21e-2)" "potential prognostic unfavorable (2.29e-4)" "unprognostic (1.49e-1)" "unprognostic (4.00e-2)" "unprognostic (7.01e-2)" "unprognostic (2.21e-2)" "potential prognostic unfavorable (4.83e-5)" "unprognostic (1.32e-2)" "potential prognostic unfavorable (9.08e-4)" "unprognostic (2.18e-2)" "potential prognostic unfavorable (4.33e-4)" "unprognostic (4.50e-2)" "unprognostic (1.19e-2)" "unprognostic (1.05e-2)" "unprognostic (2.73e-2)" "potential prognostic unfavorable (1.63e-5)" "unprognostic (8.80e-2)" "unprognostic (3.20e-2)" "unprognostic (3.32e-1)" "unprognostic (4.63e-1)" "unprognostic (7.87e-2)" "unprognostic (5.28e-1)" "unprognostic (7.21e-2)" "unprognostic (1.47e-1)" PXT1 STEPP ENSG00000179165 "Peroxisomal testis enriched protein 1" Q8NFP0 6 36390551-36442854 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "testis: 2.2" "Cell type enhanced" "Detected in many" "cDC: 7.3;Differentiating spermatogonia: 6.9;Early primary spermatocytes: 21.3;Epicardial cells: 11.4;Hematopoietic stem cells: 7.8;Megakaryocyte progenitors: 6.9;Megakaryocyte-Erythroid progenitors: 7.3;Neutrophils: 18.6" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA044042 Approved Vesicles NA NA "Cluster 67: Testis - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 65: Non-specific - Cell growth & division" Vesicles "HPA044042: " PXYLP1 "ACPL2, FLJ23751" ENSG00000155893 "2-phosphoxylose phosphatase 1" Q8TE99 3 141228726-141367753 "Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 139.9" "Cell type enhanced" "Detected in many" "Early spermatids: 176.6;Epididymal principal cells: 275.5;Late primary spermatocytes: 288.2;Late spermatids: 165.0;Renal collecting duct principal cells: 118.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Skeletal muscle - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017243 Uncertain "Intracellular and membrane" Enzyme NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 59: Leukemia - T-cell receptor" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" 2 "HPA017243: " "unprognostic (3.66e-2)" "unprognostic (2.50e-1)" "unprognostic (3.19e-1)" "unprognostic (1.23e-2)" "unprognostic (2.10e-1)" "unprognostic (1.39e-1)" "unprognostic (5.42e-2)" "unprognostic (2.48e-2)" "unprognostic (2.33e-2)" "potential prognostic favorable (1.79e-5)" "unprognostic (1.55e-1)" "unprognostic (3.27e-2)" "unprognostic (7.33e-3)" "unprognostic (2.22e-1)" "unprognostic (1.65e-2)" "unprognostic (2.66e-2)" "unprognostic (1.53e-3)" "unprognostic (3.25e-1)" "unprognostic (4.18e-2)" "unprognostic (5.27e-3)" "unprognostic (1.54e-1)" "unprognostic (1.24e-1)" "unprognostic (3.00e-1)" "unprognostic (1.81e-1)" "unprognostic (7.43e-2)" "unprognostic (2.01e-1)" "unprognostic (1.76e-1)" "unprognostic (6.27e-2)" "unprognostic (2.91e-1)" PYCARD "ASC, CARD5, TMS-1" ENSG00000103490 "PYD and CARD domain containing" Q9ULZ3 16 31201486-31203450 "Predicted intracellular proteins" "Apoptosis, Immunity, Inflammatory response, Innate immunity" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 104.6;skin 1: 111.0" "Cell type enhanced" "Detected in many" "cDC: 266.3;Colonocytes: 227.6;Enteric transient amplifying cells: 295.7;Enterocytes: 430.6;Esophageal basal cells: 257.9;Esophageal suprabasal cells: 328.6;Hofbauer cells: 539.7;Kupffer cells: 448.9;Macrophages: 223.7;Monocyte progenitors: 272.5;monocytes: 363.4;Neutrophils: 327.8;pDCs: 231.8" "Group enriched" "Detected in some" 5 "central nervous system macrophage: 49.0;leukocyte: 32.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 588.9;classical monocyte: 1101.6;eosinophil: 950.8;intermediate monocyte: 1140.1;myeloid DC: 830.8;neutrophil: 1647.4;non-classical monocyte: 1158.7;plasmacytoid DC: 771.2" "Group enriched" "Detected in all" 6 "dendritic cells: 830.8;granulocytes: 1647.4;monocytes: 1158.7" "Low cancer specificity" "Detected in many" "Adrenal gland - Macrophages, Lung - Macrophages, Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006853, CAB015948, HPA049074, HPA054496" Enhanced Supported Nucleoplasm,Nucleoli,Cytosol NA NA 390000 "Cluster 7: Non-specific - Innate immune response" "Cluster 5: Spleen - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 26 Nucleoplasm "Nucleoli, Cytosol" "CAB006853: , CAB015948: , HPA049074: , HPA054496: " "unprognostic (1.37e-1)" "unprognostic (1.66e-2)" "unprognostic (4.59e-2)" "unprognostic (3.83e-2)" "unprognostic (7.79e-2)" "unprognostic (2.33e-1)" "unprognostic (6.84e-2)" "unprognostic (2.47e-1)" "unprognostic (2.10e-1)" "unprognostic (5.14e-2)" "potential prognostic unfavorable (2.18e-5)" "unprognostic (7.92e-2)" "unprognostic (4.22e-3)" "unprognostic (7.13e-3)" "unprognostic (1.28e-1)" "unprognostic (1.06e-2)" "unprognostic (2.19e-1)" "unprognostic (1.22e-1)" "unprognostic (1.13e-1)" "unprognostic (9.80e-2)" "unprognostic (3.86e-1)" "unprognostic (2.41e-2)" "unprognostic (4.84e-2)" "unprognostic (1.02e-1)" "unprognostic (3.71e-2)" "unprognostic (1.98e-2)" "unprognostic (3.19e-1)" "unprognostic (9.02e-3)" "unprognostic (1.84e-1)" "unprognostic (1.92e-1)" "unprognostic (5.89e-2)" PYCR1 P5C ENSG00000183010 "Pyrroline-5-carboxylate reductase 1" P32322 17 81932384-81942412 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Proline biosynthesis, Stress response" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 105.4;salivary gland: 114.0" "Cell type enhanced" "Detected in many" "Breast lactating cells: 229.2;Enteric stem cells: 50.9;Extravillous trophoblasts: 110.6;Foveolar cells: 49.6;Gastric chief cells: 68.8;Gastric progenitor cells: 52.5;Goblet cells: 65.5;Late spermatids: 54.7;Pancreatic acinar cells: 56.2;Salivary acinar cells: 61.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 4.3" "Group enriched" "Detected in many" 8 "B-cells: 4.3;dendritic cells: 1.9;T-cells: 1.6" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Spleen - Plasma cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047660 Approved NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 60: Stomach - Digestion" "Cluster 19: Astrocytes - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 8: Non-specific - Secretory pathway" 37 "HPA047660: " "unprognostic (2.28e-1)" "unprognostic (3.35e-3)" "unprognostic (1.76e-1)" "unprognostic (8.24e-2)" "unprognostic (2.22e-1)" "unprognostic (8.87e-2)" "unprognostic (6.14e-2)" "unprognostic (1.18e-1)" "unprognostic (7.21e-2)" "unprognostic (2.22e-2)" "validated prognostic unfavorable (5.68e-10)" "validated prognostic unfavorable (1.36e-4)" "potential prognostic unfavorable (6.67e-8)" "potential prognostic unfavorable (9.49e-4)" "unprognostic (5.77e-3)" "unprognostic (8.78e-2)" "potential prognostic unfavorable (2.15e-4)" "unprognostic (7.27e-2)" "unprognostic (1.42e-2)" "unprognostic (8.71e-2)" "unprognostic (1.18e-2)" "unprognostic (4.83e-3)" "unprognostic (2.67e-2)" "unprognostic (5.04e-2)" "unprognostic (8.11e-2)" "unprognostic (1.97e-1)" "unprognostic (4.58e-2)" "unprognostic (7.36e-2)" "unprognostic (1.46e-1)" "unprognostic (4.95e-3)" "unprognostic (1.50e-1)" PYCR2 P5CR2 ENSG00000143811 "Pyrroline-5-carboxylate reductase 2" Q96C36 1 225919877-225924340 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Proline biosynthesis" Oxidoreductase "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 11.8;Bergmann glia: 24.3;Ependymal cells: 21.2;Microglia: 13.5;Oligodendrocyte progenitor cells: 10.4;Oligodendrocytes: 30.8;Other brain neurons: 13.2;Platelets: 25.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Pituitary gland - Undifferentiated cells (Pituitary gland)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056873 Approved Approved Mitochondria NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 22: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 98: Neurons - Neurotransmission & signaling" 40 Mitochondria "HPA056873: " "unprognostic (7.67e-3)" "unprognostic (1.30e-3)" "unprognostic (4.90e-2)" "unprognostic (4.66e-1)" "unprognostic (1.93e-2)" "unprognostic (6.75e-3)" "unprognostic (1.08e-1)" "unprognostic (1.79e-1)" "unprognostic (1.94e-2)" "unprognostic (3.28e-2)" "unprognostic (2.55e-2)" "unprognostic (6.18e-2)" "unprognostic (2.69e-2)" "unprognostic (5.91e-3)" "unprognostic (3.28e-2)" "unprognostic (1.69e-1)" "unprognostic (1.62e-1)" "unprognostic (4.63e-3)" "unprognostic (1.39e-1)" "unprognostic (7.72e-2)" "unprognostic (8.34e-2)" "unprognostic (9.00e-2)" "unprognostic (1.41e-1)" "unprognostic (2.62e-2)" "unprognostic (2.32e-3)" "unprognostic (1.83e-2)" "unprognostic (1.02e-1)" "unprognostic (2.03e-1)" "unprognostic (4.32e-2)" "unprognostic (1.03e-1)" "unprognostic (4.61e-1)" PYCR3 "FLJ13852, PYCRL" ENSG00000104524 "Pyrroline-5-carboxylate reductase 3" Q53H96 8 143603210-143609773 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Amino-acid biosynthesis, Proline biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 3.0;Bergmann glia: 3.1;Brain excitatory neurons: 5.2;Brain inhibitory neurons: 4.5;Choroid plexus epithelial cells: 2.4;Ependymal cells: 9.7;Loop of henle epithelial cells: 2.5;Oligodendrocyte progenitor cells: 2.2;Oligodendrocytes: 2.7;Other brain neurons: 4.9;Papillary tip epithelial cells: 2.6;Podocytes: 2.1;Proximal tubule cells: 3.1;Renal collecting duct principal cells: 2.9;Renal connecting tubule cells: 2.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 4.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Prostate - Prostate glandular cells, Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053776, HPA063416, HPA069706" Uncertain Supported "Cytokinetic bridge,Mitotic spindle,Cytosol" Yes NA "Cluster 14: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" 30 Cytosol "Cytokinetic bridge, Mitotic spindle" "HPA053776: , HPA063416: , HPA069706: " "unprognostic (1.10e-1)" "unprognostic (3.89e-2)" "unprognostic (3.49e-2)" "unprognostic (1.82e-1)" "unprognostic (4.09e-2)" "unprognostic (3.28e-2)" "unprognostic (3.65e-2)" "unprognostic (3.12e-1)" "unprognostic (6.17e-2)" "potential prognostic unfavorable (2.86e-8)" "unprognostic (2.46e-2)" "unprognostic (4.03e-2)" "potential prognostic unfavorable (2.52e-4)" "unprognostic (1.48e-2)" "unprognostic (5.95e-2)" "unprognostic (1.31e-2)" "unprognostic (3.03e-1)" "unprognostic (1.98e-3)" "unprognostic (2.19e-1)" "unprognostic (8.55e-3)" "unprognostic (1.20e-3)" "unprognostic (6.94e-3)" "unprognostic (3.20e-1)" "unprognostic (1.70e-1)" "unprognostic (8.72e-2)" "unprognostic (2.67e-2)" "unprognostic (2.38e-1)" "unprognostic (7.12e-2)" "unprognostic (1.19e-1)" PYDC1 "ASC2, POP1" ENSG00000169900 "Pyrin domain containing 1" Q8WXC3 16 31215962-31217135 "Predicted intracellular proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "brain: 25.5;skin 1: 22.0" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 3.9;Brain inhibitory neurons: 1.4;Breast hormone-responsive cells: 2.7;Breast myoepithelial cells: 2.6;Breast secretory cells: 1.5;Epicardial cells: 4.5;Myonuclei: 1.9;Other brain neurons: 2.6;Schwann cells: 1.4;Suprabasal keratinocytes: 4.8;Thymic myoid cells: 2.7" "Cell type enhanced" "Detected in some" "upper rhombic lip: 8.2" "Cancer enriched" "Detected in many" 5 "Breast Invasive Carcinoma (TCGA): 20.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 34 "breast cancer: 11.7" NA NA "Cluster 2: Non-specific - Mixed function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 27: Breast cancer - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" 1 "unprognostic (1.04e-1)" "unprognostic (1.21e-2)" "unprognostic (3.60e-2)" "unprognostic (3.88e-3)" "unprognostic (8.66e-2)" "unprognostic (3.79e-1)" "unprognostic (2.64e-2)" "unprognostic (1.40e-1)" PYDC2 POP2 ENSG00000253548 "Pyrin domain containing 2" Q56P42 3 191461163-191461456 "Predicted intracellular proteins" "Immunity, Inflammatory response, Innate immunity" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebral cortex: 9.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035819, HPA055895" Uncertain Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 53: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" 2 "Nucleoplasm, Nucleoli" Cytosol "HPA035819: , HPA055895: " "unprognostic (3.12e-1)" PYDC5 POP3 ENSG00000289721 "Pyrin domain containing 5" W6CW81 1 158999971-159002751 "Essential proteins, Predicted intracellular proteins" "Inflammatory response" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 4 "Epicardial cells: 43.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 30: White matter - Myelination" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" PYGB ENSG00000100994 "Glycogen phosphorylase B" P11216 20 25248085-25298012 "Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Allosteric enzyme, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 165.4;Lacrimal acinar cells: 170.3;Salivary basal cells: 187.8;Salivary duct cells: 282.6;Salivary ionocytes: 173.0;Smooth muscle cells: 174.5;Somatotrophs: 212.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells (progenitors), Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031067 Approved Approved Cytosol NA NA 7500000 "Cluster 33: Non-specific - ATP binding" "Cluster 35: Non-specific - Mixed function" "Cluster 45: Non-specific - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 27 Cytosol "HPA031067: " "unprognostic (2.03e-1)" "unprognostic (2.21e-2)" "unprognostic (2.50e-1)" "unprognostic (3.44e-3)" "unprognostic (9.03e-2)" "unprognostic (1.66e-1)" "unprognostic (1.13e-1)" "unprognostic (2.98e-3)" "unprognostic (1.57e-2)" "unprognostic (4.60e-2)" "validated prognostic unfavorable (2.71e-4)" "validated prognostic unfavorable (1.58e-4)" "unprognostic (2.00e-1)" "potential prognostic unfavorable (1.08e-4)" "unprognostic (5.49e-2)" "unprognostic (8.27e-3)" "unprognostic (3.25e-2)" "potential prognostic unfavorable (7.31e-5)" "unprognostic (1.38e-2)" "unprognostic (1.97e-3)" "unprognostic (6.91e-2)" "potential prognostic unfavorable (6.33e-4)" "unprognostic (1.45e-1)" "unprognostic (4.35e-1)" "unprognostic (1.96e-1)" "unprognostic (1.61e-1)" "unprognostic (7.37e-3)" "unprognostic (4.29e-2)" "unprognostic (2.73e-1)" "unprognostic (2.48e-1)" "unprognostic (1.57e-1)" PYGL GSD6 ENSG00000100504 "Glycogen phosphorylase L" P06737 14 50857891-50944483 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Allosteric enzyme, Glycosyltransferase, Transferase" "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 136.2" "Cell type enhanced" "Detected in many" "Adipocytes: 307.4;Esophageal apical cells: 247.9;Extravillous trophoblasts: 218.8;Hofbauer cells: 436.6;Müller glia: 443.4;Neutrophil progenitors: 732.1;Neutrophils: 1659.3;Platelets: 280.7" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 75.8;oligodendrocyte precursor cell: 59.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 141.4;neutrophil: 154.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Lung - Neutrophils_2, Spleen - Neutrophils_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA000962, HPA004119" Enhanced Approved "Plasma membrane,Cytosol" NA NA 21000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 17 "Plasma membrane, Cytosol" "HPA000962: , HPA004119: " "unprognostic (8.64e-2)" "unprognostic (1.25e-2)" "unprognostic (1.08e-1)" "unprognostic (3.87e-3)" "unprognostic (5.03e-2)" "unprognostic (1.07e-2)" "unprognostic (3.96e-2)" "potential prognostic unfavorable (9.63e-4)" "potential prognostic unfavorable (4.55e-4)" "unprognostic (3.21e-1)" "unprognostic (6.55e-3)" "unprognostic (1.22e-1)" "unprognostic (1.78e-1)" "unprognostic (2.28e-1)" "unprognostic (1.72e-1)" "validated prognostic unfavorable (2.16e-4)" "validated prognostic unfavorable (8.19e-4)" "unprognostic (2.72e-1)" "unprognostic (3.75e-2)" "unprognostic (7.51e-3)" "unprognostic (8.51e-2)" "potential prognostic unfavorable (5.93e-4)" "unprognostic (7.61e-3)" "unprognostic (7.64e-3)" "unprognostic (2.81e-2)" "unprognostic (1.44e-2)" "unprognostic (2.27e-1)" "unprognostic (1.58e-2)" "unprognostic (1.92e-1)" "unprognostic (7.89e-2)" "unprognostic (9.60e-2)" PYGM GSD5 ENSG00000068976 "Glycogen phosphorylase, muscle associated" P11217 11 64746389-64759974 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Allosteric enzyme, Glycosyltransferase, Transferase" "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 65 "skeletal muscle: 7932.8;tongue: 3356.6" "Cell type enriched" "Detected in many" 4 "Myonuclei: 357.6" "Group enriched" "Detected in many" 4 "astrocyte: 63.4;cerebellar inhibitory: 21.2;pericyte: 20.4;vascular associated smooth muscle cell: 19.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "basophil: 8.3" "Lineage enriched" "Detected in many" 6 "granulocytes: 8.3" "Cancer enriched" "Detected in some" 10 "Rhabdoid: 24.5" "Adrenal gland - Fibroblasts, Heart muscle - Cardiomyocytes, Kidney - Fibroblasts, Pancreas - Fibroblasts, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056003 Enhanced NA NA 6000000 "Cluster 32: Basophils - Transcription" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 19: Astrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 30 "HPA056003: " "unprognostic (5.38e-2)" "unprognostic (2.55e-2)" "unprognostic (6.77e-3)" "unprognostic (6.26e-2)" "unprognostic (1.29e-2)" "unprognostic (6.39e-3)" "unprognostic (2.27e-3)" "unprognostic (1.50e-3)" "unprognostic (1.60e-3)" "unprognostic (3.16e-2)" "unprognostic (1.33e-1)" "unprognostic (1.13e-1)" "unprognostic (1.01e-1)" "unprognostic (1.94e-3)" "unprognostic (2.17e-1)" "unprognostic (1.08e-2)" "unprognostic (3.74e-2)" PYGO1 ENSG00000171016 "Pygopus family PHD finger 1" Q9Y3Y4 15 55538884-55588947 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 12.4" "Cell type enhanced" "Detected in many" "Gonadotrophs: 79.2;Myonuclei: 142.4;Oligodendrocyte progenitor cells: 93.6;Somatotrophs: 121.6" "Cell type enhanced" "Detected in many" "oligodendrocyte precursor cell: 116.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatic stellate cells, Minor Salivary Gland - Endothelial cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042248 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 55: Lymphoma - Immune response" "Cluster 108: Fibroblasts - ECM organization" 7 Nucleoplasm Cytosol "HPA042248: " "unprognostic (4.07e-1)" "unprognostic (8.91e-2)" "unprognostic (3.45e-1)" "unprognostic (1.71e-1)" "unprognostic (1.01e-1)" "unprognostic (2.16e-1)" "unprognostic (1.27e-1)" "unprognostic (3.82e-1)" "unprognostic (5.53e-2)" "unprognostic (8.60e-2)" "unprognostic (5.91e-2)" "unprognostic (3.22e-1)" "unprognostic (1.21e-1)" "unprognostic (2.62e-1)" "unprognostic (8.20e-2)" "unprognostic (8.39e-2)" "potential prognostic unfavorable (6.79e-5)" "unprognostic (4.87e-2)" "unprognostic (2.92e-2)" "unprognostic (9.00e-2)" PYGO2 ENSG00000163348 "Pygopus family PHD finger 2" Q9BRQ0 1 154957026-154963853 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023689, HPA074813" Supported Supported "Nucleoplasm,Plasma membrane" No No "Cluster 3: Non-specific - Nuclear processes" "Cluster 64: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 45: Non-specific - Nuclear processes" "Cluster 9: T-cells - Adaptive immunity: Regulation" 13 Nucleoplasm "Plasma membrane" "HPA023689: , HPA074813: " "unprognostic (2.22e-1)" "unprognostic (1.23e-1)" "unprognostic (2.69e-1)" "unprognostic (7.87e-2)" "unprognostic (1.13e-2)" "unprognostic (2.77e-1)" "unprognostic (2.01e-1)" "unprognostic (1.95e-2)" "unprognostic (6.45e-3)" "unprognostic (4.74e-2)" "unprognostic (1.24e-1)" "unprognostic (9.35e-2)" "unprognostic (2.92e-1)" "potential prognostic unfavorable (3.27e-6)" "unprognostic (5.43e-2)" "unprognostic (1.52e-1)" "unprognostic (3.66e-2)" "unprognostic (1.41e-1)" "unprognostic (1.05e-2)" "unprognostic (4.46e-2)" "unprognostic (1.17e-1)" "unprognostic (2.06e-1)" "unprognostic (4.36e-2)" "unprognostic (2.48e-1)" "unprognostic (1.34e-1)" "unprognostic (1.09e-1)" "unprognostic (3.09e-2)" "unprognostic (9.05e-2)" "unprognostic (9.76e-2)" "unprognostic (1.27e-1)" "unprognostic (1.18e-1)" PYHIN1 "IFIX, MGC23885" ENSG00000163564 "Pyrin and HIN domain family member 1" Q6K0P9 1 158930796-158977059 "Predicted intracellular proteins" "Cell cycle" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 21.6" "Group enriched" "Detected in some" 9 "NK-cells: 495.0;T-cells: 244.0" "Cell type enriched" "Detected in some" 242 "leukocyte: 320.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 97.4;MAIT T-cell: 56.3;memory CD4 T-cell: 40.9;memory CD8 T-cell: 74.6;naive CD8 T-cell: 45.2;NK-cell: 36.8;T-reg: 67.4" "Group enriched" "Detected in many" 5 "NK-cells: 36.8;T-cells: 97.4" "Cancer enriched" "Detected in some" 6 "lymphoma: 15.7" "Adipose visceral - T-cells, Adrenal gland - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Lung - NK-cells (Lung), Minor Salivary Gland - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Thyroid gland - T-cells" "HPA051224, HPA055373" Enhanced Approved Nucleoplasm,Nucleoli NA NA "Cluster 1: T-cells - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 37 Nucleoli Nucleoplasm "HPA051224: , HPA055373: " "unprognostic (1.99e-2)" "potential prognostic favorable (7.82e-5)" "unprognostic (3.27e-2)" "potential prognostic favorable (2.74e-4)" "unprognostic (3.15e-1)" "unprognostic (3.14e-3)" "unprognostic (2.05e-1)" "unprognostic (2.95e-1)" "unprognostic (2.78e-3)" "unprognostic (9.41e-3)" "potential prognostic favorable (7.96e-5)" "unprognostic (2.76e-1)" "unprognostic (8.80e-2)" "unprognostic (2.04e-1)" "unprognostic (1.50e-2)" "potential prognostic unfavorable (5.53e-4)" "unprognostic (1.29e-2)" "unprognostic (4.75e-1)" "unprognostic (2.03e-1)" "unprognostic (1.11e-1)" "unprognostic (1.49e-1)" PYM1 "PYM, WIBG" ENSG00000170473 "PYM homolog 1, exon junction complex associated factor" Q9BRP8 12 55901413-55932618 "Predicted intracellular proteins" "Nonsense-mediated mRNA decay, Translation regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 487.0;Esophageal suprabasal cells: 195.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012803, HPA039717, HPA046200" Supported Supported "Nucleoplasm,Nucleoli,Cell Junctions,Cytosol" No No 100000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 85: Squamous epithelial cells - Keratinization" 16 "Nucleoplasm, Nucleoli, Cytosol" "Cell Junctions" "CAB012803: , HPA039717: , HPA046200: " "unprognostic (4.92e-1)" "unprognostic (3.55e-2)" "unprognostic (6.83e-2)" "unprognostic (1.47e-1)" "unprognostic (6.14e-2)" "unprognostic (1.02e-1)" "unprognostic (8.02e-2)" "unprognostic (5.18e-2)" "unprognostic (1.08e-2)" "potential prognostic unfavorable (3.24e-4)" "unprognostic (2.82e-2)" "unprognostic (6.95e-2)" "potential prognostic unfavorable (2.70e-5)" "unprognostic (4.22e-3)" "unprognostic (1.35e-1)" "unprognostic (1.06e-1)" "unprognostic (5.57e-2)" "unprognostic (1.31e-2)" "unprognostic (1.43e-1)" "unprognostic (7.84e-2)" "unprognostic (2.18e-1)" "unprognostic (2.93e-1)" "unprognostic (1.33e-1)" "unprognostic (8.97e-2)" "unprognostic (4.13e-2)" "unprognostic (5.99e-2)" "unprognostic (3.04e-1)" "unprognostic (3.65e-1)" "unprognostic (2.24e-3)" PYROXD1 "DKFZp762G094, FLJ22028" ENSG00000121350 "Pyridine nucleotide-disulphide oxidoreductase domain 1" Q8WU10 12 21437615-21471250 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" Oxidoreductase "Disease variant, Limb-girdle muscular dystrophy, Myofibrillar myopathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038319, HPA038320" Uncertain Approved "Nuclear speckles" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 76: Non-specific - Metabolism" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 7: Non-specific - Transcription" 1 "Nuclear speckles" "HPA038319: , HPA038320: " "unprognostic (3.55e-2)" "unprognostic (2.68e-2)" "unprognostic (2.16e-2)" "unprognostic (4.04e-2)" "unprognostic (1.18e-2)" "unprognostic (1.56e-1)" "unprognostic (1.10e-1)" "unprognostic (2.41e-2)" "unprognostic (3.02e-2)" "unprognostic (2.83e-1)" "potential prognostic favorable (2.43e-5)" "unprognostic (1.86e-1)" "unprognostic (3.02e-2)" "unprognostic (1.01e-2)" "unprognostic (2.53e-2)" "unprognostic (2.83e-2)" "unprognostic (5.05e-2)" "unprognostic (1.18e-2)" "unprognostic (1.50e-1)" "unprognostic (1.55e-1)" "unprognostic (9.71e-3)" "unprognostic (2.45e-1)" "unprognostic (6.27e-2)" "unprognostic (3.95e-2)" "unprognostic (3.49e-1)" "unprognostic (1.13e-1)" "unprognostic (7.26e-2)" "unprognostic (6.87e-2)" "unprognostic (1.40e-2)" "unprognostic (2.80e-2)" "unprognostic (1.66e-1)" PYROXD2 "C10orf33, FLJ23849" ENSG00000119943 "Pyridine nucleotide-disulphide oxidoreductase domain 2" Q8N2H3 10 98383565-98415182 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 38.3;Prostatic club cells: 30.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "eosinophil: 190.9" "Lineage enriched" "Detected in many" 4 "granulocytes: 190.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA037566, HPA037567, HPA067394" Approved Approved Mitochondria NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 46: Brainstem - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 2 Mitochondria "HPA037566: , HPA037567: , HPA067394: " "unprognostic (1.93e-2)" "unprognostic (8.88e-2)" "unprognostic (5.18e-2)" "unprognostic (1.12e-1)" "unprognostic (1.02e-1)" "unprognostic (3.72e-2)" "unprognostic (1.49e-3)" "unprognostic (3.53e-2)" "unprognostic (1.55e-1)" "potential prognostic favorable (2.70e-4)" "unprognostic (1.52e-2)" "potential prognostic favorable (3.72e-4)" "unprognostic (2.94e-2)" "unprognostic (1.15e-1)" "unprognostic (1.22e-1)" "unprognostic (1.71e-1)" "unprognostic (7.12e-3)" "unprognostic (1.08e-1)" "unprognostic (8.16e-2)" "unprognostic (1.51e-2)" "unprognostic (2.66e-1)" "unprognostic (1.65e-2)" "unprognostic (3.49e-1)" "unprognostic (9.58e-2)" "unprognostic (2.15e-2)" "unprognostic (7.05e-2)" "unprognostic (8.61e-2)" "unprognostic (1.25e-1)" "unprognostic (5.84e-3)" "unprognostic (1.05e-1)" PYURF PreY ENSG00000145337 "PIGY upstream open reading frame" Q96I23 4 88520998-88523776 "Disease related genes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 12 "Distal convoluted tubule cells: 5.1;Loop of henle epithelial cells: 6.8;Papillary tip epithelial cells: 10.0;Podocytes: 9.3;Proximal tubule cells: 4.4;Renal collecting duct intercalated cells: 5.1;Renal collecting duct principal cells: 8.9;Renal connecting tubule cells: 4.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA036455 Uncertain Approved Nucleoplasm NA Yes "Cluster 9: T-regs - Cell cycle regulation" "Cluster 76: Non-specific - Metabolism" "Cluster 27: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 1 Nucleoplasm "HPA036455: " "unprognostic (9.06e-2)" "unprognostic (1.96e-1)" "unprognostic (4.00e-1)" "unprognostic (7.29e-3)" "unprognostic (9.66e-3)" "unprognostic (2.74e-1)" "unprognostic (5.27e-2)" "unprognostic (4.38e-2)" "unprognostic (8.71e-2)" "potential prognostic favorable (2.75e-6)" "unprognostic (2.47e-3)" "unprognostic (2.65e-2)" "unprognostic (1.44e-1)" "unprognostic (1.52e-1)" "unprognostic (9.86e-2)" "unprognostic (9.57e-2)" "unprognostic (4.54e-2)" "unprognostic (2.10e-1)" "unprognostic (6.15e-3)" "unprognostic (1.59e-1)" "unprognostic (1.61e-1)" "unprognostic (1.42e-2)" "unprognostic (1.65e-1)" "unprognostic (5.92e-2)" "unprognostic (8.46e-2)" "unprognostic (1.22e-1)" "unprognostic (7.56e-2)" "unprognostic (3.36e-1)" "unprognostic (2.13e-2)" PYY PYY1 ENSG00000131096 "Peptide YY" P10082 17 43952733-44004469 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 33 "intestine: 66.2" "Cell type enriched" "Detected in many" 146 "Neuroendocrine cells: 21711.6" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 28.3;Testicular Germ Cell Tumor (TCGA): 43.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "liver cancer: 9.9;Neuroblastoma: 2.7" "Colon - Colon enterocytes" "Region enriched" "Detected in single" 14 "pons and medulla: 1.4" "Low region specificity" "Detected in some" "HPA010973, CAB016734" Enhanced "Secreted to blood" Hormone NA NA 87100 "Cluster 77: Intestine - Digestion" "Cluster 9: Non-specific - Receptor signaling" "Cluster 18: Liver cancer - Metabolism" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" "CAB016734: , HPA010973: " "unprognostic (5.38e-2)" "unprognostic (2.62e-2)" "unprognostic (3.29e-1)" "unprognostic (6.93e-2)" "unprognostic (6.40e-3)" "unprognostic (2.56e-2)" "unprognostic (9.31e-2)" "unprognostic (1.39e-1)" "unprognostic (1.92e-2)" "unprognostic (2.40e-2)" "unprognostic (4.35e-1)" "unprognostic (8.76e-2)" PZP CPAMD6 ENSG00000126838 "PZP alpha-2-macroglobulin like" P20742 12 9148840-9208395 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 35 "liver: 76.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 199.7;Ependymal cells: 196.9;Hepatocytes: 71.2;Mast cells: 268.4;Myonuclei: 74.7;NK-cells: 55.8;Respiratory ciliated cells: 153.5;T-cells: 71.9" "Group enriched" "Detected in many" 5 "ependymal cell: 171.8;leukocyte: 66.1" "Cancer enhanced" "Detected in some" "Liver Hepatocellular Carcinoma (TCGA): 1.3;Uterine Corpus Endometrial Carcinoma (TCGA): 1.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 1.1;MAIT T-cell: 1.1" "Lineage enriched" "Detected in single" 11 "T-cells: 1.1" "Cancer enriched" "Detected in single" 9 "cervical cancer: 1.9" "Adipose subcutaneous - Endothelial cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "HPA041403, HPA041471" Supported "Secreted to blood" "Enzyme inhibitor" NA NA 34000000000 "Cluster 1: T-cells - Unknown function" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 46: Brainstem - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 9: T-cells - Adaptive immunity: Regulation" 1 "HPA041403: , HPA041471: " "unprognostic (1.44e-3)" "unprognostic (9.07e-3)" "unprognostic (5.32e-1)" QARS1 QARS ENSG00000172053 "Glutaminyl-tRNA synthetase 1" P47897 3 49095932-49105130 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Epilepsy, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 237.9;Early spermatids: 229.1;Esophageal apical cells: 249.6;Late spermatids: 913.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036986, HPA036987" Enhanced Enhanced Cytosol No No 110000 "Cluster 13: Non-specific - Mitochondria" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 25: Non-specific - Ribosome" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 104 Cytosol "HPA036986: , HPA036987: " "unprognostic (4.11e-1)" "unprognostic (4.29e-2)" "unprognostic (4.46e-2)" "unprognostic (3.68e-2)" "unprognostic (2.16e-1)" "unprognostic (2.85e-2)" "unprognostic (1.07e-1)" "unprognostic (1.50e-2)" "unprognostic (5.76e-3)" "potential prognostic favorable (1.16e-7)" "unprognostic (7.26e-2)" "unprognostic (5.63e-3)" "unprognostic (8.72e-3)" "unprognostic (3.62e-1)" "unprognostic (5.56e-2)" "unprognostic (2.82e-1)" "unprognostic (2.80e-1)" "unprognostic (1.60e-1)" "unprognostic (6.44e-2)" "unprognostic (7.75e-2)" "unprognostic (9.82e-2)" "unprognostic (2.44e-1)" "unprognostic (1.54e-2)" "unprognostic (3.50e-1)" "unprognostic (1.36e-2)" "unprognostic (2.30e-2)" "unprognostic (1.49e-1)" "unprognostic (7.04e-3)" "unprognostic (7.87e-2)" QDPR "DHPR, PKU2, SDR33C1" ENSG00000151552 "Quinoid dihydropteridine reductase" P09417 4 17460261-17512206 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tetrahydrobiopterin biosynthesis" Oxidoreductase "Disease variant, Phenylketonuria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "brain: 782.0;liver: 209.2" "Cell type enhanced" "Detected in many" "Hepatocytes: 438.0;Müller glia: 320.4;Neuroendocrine cells: 220.7;Oligodendrocytes: 654.6;Pancreatic islet cells: 174.6" "Group enriched" "Detected in all" 6 "committed oligodendrocyte precursor: 252.1;oligodendrocyte: 754.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Pituitary gland - Thyrotropes, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058951, HPA065649" Enhanced Approved Mitochondria NA NA 2500000 "Cluster 13: Non-specific - Mitochondria" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 47: Endothelial cells - Vasculature" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 11: Muller glia cells - Retinal homeostasis" 1 Mitochondria "HPA058951: , HPA065649: " "unprognostic (2.81e-1)" "unprognostic (1.53e-2)" "unprognostic (2.29e-1)" "unprognostic (2.62e-2)" "unprognostic (7.04e-2)" "unprognostic (9.54e-2)" "unprognostic (8.30e-2)" "unprognostic (6.56e-2)" "unprognostic (2.97e-1)" "unprognostic (2.25e-2)" "potential prognostic favorable (8.32e-6)" "unprognostic (1.42e-2)" "potential prognostic favorable (4.53e-5)" "unprognostic (2.92e-3)" "unprognostic (2.22e-1)" "unprognostic (1.57e-1)" "unprognostic (3.37e-1)" "unprognostic (2.18e-2)" "unprognostic (1.36e-1)" "unprognostic (3.40e-2)" "unprognostic (1.24e-1)" "unprognostic (7.92e-3)" "unprognostic (2.86e-1)" "unprognostic (1.01e-1)" "unprognostic (1.10e-1)" "unprognostic (3.48e-1)" "unprognostic (4.07e-2)" "unprognostic (3.99e-1)" "unprognostic (3.97e-1)" "unprognostic (2.42e-2)" "unprognostic (9.52e-3)" QKI QK3 ENSG00000112531 "QKI, KH domain containing RNA binding" Q96PU8 6 163414000-163578592 "Cancer-related genes, Predicted intracellular proteins" "Differentiation, mRNA processing, mRNA splicing, mRNA transport, Translation regulation, Transport" "Developmental protein, DNA-binding, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 290.1;tongue: 207.3" "Cell type enhanced" "Detected in many" "Astrocytes: 1812.3;Bergmann glia: 2279.1;Microglia: 1857.9;Myonuclei: 3258.7;Neutrophils: 3082.4;Oligodendrocyte progenitor cells: 1948.4;Oligodendrocytes: 5472.3" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 4394.7;oligodendrocyte: 7417.4" "Cancer enriched" "Detected in all" 5 "Glioblastoma Multiforme (TCGA): 172.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019123, CAB022602" Enhanced Supported Supported Nucleoplasm NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 55: Myocytes - Oxidative muscle function" 51 Nucleoplasm "CAB022602: , HPA019123: " "unprognostic (1.34e-3)" "unprognostic (6.87e-2)" "unprognostic (1.29e-1)" "unprognostic (1.09e-2)" "unprognostic (3.19e-2)" "unprognostic (7.13e-2)" "unprognostic (6.54e-2)" "unprognostic (1.93e-1)" "unprognostic (1.17e-1)" "unprognostic (4.51e-3)" "potential prognostic favorable (1.29e-5)" "unprognostic (1.41e-2)" "unprognostic (1.42e-1)" "unprognostic (1.22e-1)" "unprognostic (8.10e-2)" "unprognostic (1.06e-2)" "unprognostic (3.66e-2)" "unprognostic (2.50e-2)" "unprognostic (3.73e-1)" "unprognostic (1.80e-3)" "unprognostic (8.87e-3)" "unprognostic (5.25e-2)" "unprognostic (1.34e-3)" "unprognostic (1.10e-1)" "unprognostic (5.18e-2)" "unprognostic (3.21e-2)" "unprognostic (2.11e-1)" "unprognostic (1.35e-3)" "unprognostic (1.28e-1)" "unprognostic (9.34e-2)" "unprognostic (2.33e-1)" QPCT "GCT, QC" ENSG00000115828 "Glutaminyl-peptide cyclotransferase" Q16769 2 37342827-37373322 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 162.3;epididymis: 98.2" "Group enriched" "Detected in many" 4 "Melanocytes: 857.0;Neutrophils: 459.8;Pancreatic islet cells: 280.8" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 226.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 1536.9" "Lineage enriched" "Detected in many" 4 "granulocytes: 1536.9" "Group enriched" "Detected in all" 6 "Myeloma: 99.3;skin cancer: 291.9" "Adipose visceral - Neutrophils, Adrenal gland - Adrenal cortex cells, Lung - Neutrophils_2, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008406 Enhanced Approved Cytosol "Secreted to blood" Enzyme NA NA 2900000 "Cluster 21: Neutrophils - Unknown function" "Cluster 22: Epididymis - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 3 Cytosol "HPA008406: " "unprognostic (2.12e-1)" "unprognostic (1.87e-2)" "unprognostic (1.02e-1)" "unprognostic (1.71e-2)" "unprognostic (2.85e-3)" "unprognostic (3.28e-3)" "unprognostic (1.10e-2)" "unprognostic (2.94e-2)" "unprognostic (5.94e-2)" "unprognostic (1.97e-2)" "unprognostic (3.09e-3)" "unprognostic (2.19e-1)" "unprognostic (2.92e-2)" "unprognostic (1.51e-3)" "unprognostic (6.81e-3)" "unprognostic (3.84e-1)" "unprognostic (1.81e-1)" "unprognostic (2.68e-2)" "unprognostic (5.95e-2)" "unprognostic (8.54e-2)" "unprognostic (5.34e-3)" "unprognostic (3.70e-2)" "unprognostic (2.19e-2)" "unprognostic (3.72e-1)" "unprognostic (1.39e-1)" "unprognostic (2.32e-2)" "unprognostic (1.86e-2)" "unprognostic (1.00e-2)" "unprognostic (3.89e-2)" "unprognostic (2.52e-3)" "unprognostic (3.54e-1)" QPCTL FLJ20084 ENSG00000011478 "Glutaminyl-peptide cyclotransferase like" Q9NXS2 19 45692403-45703989 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Plasma cells: 33.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040797 Approved Supported "Golgi apparatus" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 63: Non-specific - Protein processing" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 2 "Golgi apparatus" "HPA040797: " "unprognostic (4.52e-2)" "unprognostic (5.35e-2)" "unprognostic (1.89e-1)" "unprognostic (1.91e-2)" "unprognostic (7.20e-2)" "unprognostic (3.06e-2)" "unprognostic (1.45e-1)" "unprognostic (5.65e-2)" "unprognostic (3.69e-2)" "unprognostic (1.14e-2)" "potential prognostic unfavorable (1.97e-4)" "unprognostic (7.94e-3)" "unprognostic (6.39e-2)" "unprognostic (6.16e-3)" "unprognostic (1.96e-3)" "unprognostic (1.99e-2)" "unprognostic (2.15e-1)" "unprognostic (1.69e-1)" "unprognostic (7.66e-2)" "unprognostic (2.78e-1)" "unprognostic (2.98e-1)" "unprognostic (1.11e-1)" "unprognostic (1.78e-1)" "unprognostic (1.66e-1)" "unprognostic (2.45e-3)" "potential prognostic favorable (6.64e-4)" "unprognostic (2.23e-1)" "unprognostic (1.48e-1)" "unprognostic (2.13e-1)" "unprognostic (2.01e-2)" "unprognostic (1.37e-1)" QPRT QPRTase ENSG00000103485 "Quinolinate phosphoribosyltransferase" Q15274 16 29663279-29698699 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Glycosyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 220.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 487.9;Epididymal efferent duct absorptive cells: 217.2;Epididymal principal cells: 454.0;Extravillous trophoblasts: 413.2;Hepatocytes: 368.0;Hofbauer cells: 234.4;Migrating cytotrophoblasts: 399.7;Syncytiotrophoblasts: 218.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 4.3;intermediate monocyte: 5.3;myeloid DC: 5.9;non-classical monocyte: 9.1;plasmacytoid DC: 3.1" "Group enriched" "Detected in many" 8 "dendritic cells: 5.9;monocytes: 9.1" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Fibroblasts, Stomach - Chief cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA011887, HPA076010" Enhanced Approved Vesicles NA NA 690000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 15 Vesicles "HPA011887: , HPA076010: " "unprognostic (6.57e-3)" "potential prognostic unfavorable (4.34e-5)" "unprognostic (1.90e-2)" "unprognostic (6.66e-2)" "unprognostic (4.27e-2)" "unprognostic (2.15e-2)" "unprognostic (1.34e-3)" "unprognostic (1.23e-3)" "unprognostic (6.90e-2)" "unprognostic (1.05e-1)" "unprognostic (7.07e-2)" "unprognostic (3.83e-2)" "unprognostic (2.65e-2)" "unprognostic (3.17e-2)" "unprognostic (2.66e-3)" "unprognostic (5.51e-2)" "unprognostic (2.47e-1)" "unprognostic (1.48e-2)" "unprognostic (1.84e-2)" "unprognostic (1.12e-1)" "unprognostic (9.62e-2)" "unprognostic (1.54e-1)" "unprognostic (4.94e-3)" "unprognostic (5.04e-2)" "unprognostic (1.20e-2)" "unprognostic (1.61e-1)" "unprognostic (9.57e-2)" "unprognostic (2.41e-3)" "unprognostic (2.71e-1)" "unprognostic (4.74e-2)" "unprognostic (6.37e-2)" QRFP "26RFa, P518, prepro-26RFa" ENSG00000188710 "Pyroglutamylated RFamide peptide" P83859 9 130892707-130896812 "Predicted secreted proteins" Neuropeptide "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Epicardial cells: 4.5;Fibro-adipogenic progenitors: 1.1;Hofbauer cells: 1.0;Müller glia: 1.1;Prostatic glandular cells: 1.0;Retinal amacrine cells: 2.1;Salivary myoepithelial cells: 1.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "intermediate monocyte: 1.0" "Lineage enriched" "Detected in single" 11 "monocytes: 1.0" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA043377 Uncertain "Secreted in other tissues" Neuropeptide NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 6: Non-specific - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "HPA043377: " "unprognostic (8.01e-2)" "unprognostic (4.06e-3)" "unprognostic (9.08e-3)" "unprognostic (1.39e-2)" "unprognostic (1.93e-1)" QRFPR GPR103 ENSG00000186867 "Pyroglutamylated RFamide peptide receptor" Q96P65 4 121328642-121381059 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.1;heart muscle: 1.2;kidney: 1.0" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 4.2;Brain inhibitory neurons: 3.9;Cardiomyocytes: 7.0;Early spermatids: 9.4;Late spermatids: 7.2;Other brain neurons: 42.2;Pituicytes/FSCs: 11.8;Proximal tubule cells: 6.2;Thymic myoid cells: 12.2;Vascular endothelial cells: 6.0" "Cell type enhanced" "Detected in many" "deep-layer near-projecting: 86.2;lower rhombic lip: 46.3" "Group enriched" "Detected in some" 6 "Kidney Renal Clear Cell Carcinoma (TCGA): 9.8;Kidney Renal Papillary Cell Carcinoma (TCGA): 10.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 1.4" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in some" "Bone cancer: 3.8;Kidney cancer: 4.2" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA050236 Approved NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 24: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 109: Neurons - Neuronal signaling" 1 "HPA050236: " "unprognostic (3.43e-1)" "unprognostic (4.15e-1)" "unprognostic (1.08e-1)" "validated prognostic favorable (1.38e-8)" "validated prognostic favorable (5.16e-4)" "potential prognostic favorable (4.36e-4)" "unprognostic (3.25e-2)" "unprognostic (2.30e-1)" QRICH1 "AB-DIP, FLJ20259, VERBRAS" ENSG00000198218 "Glutamine rich 1" Q2TAL8 3 49029707-49094363 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation, Unfolded protein response" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 34.4;Bergmann glia: 36.6;Brain excitatory neurons: 62.6;Brain inhibitory neurons: 61.0;Choroid plexus epithelial cells: 91.3;Distal convoluted tubule cells: 73.5;Ependymal cells: 30.1;Loop of henle epithelial cells: 62.0;Microglia: 48.1;Oligodendrocyte progenitor cells: 42.4;Oligodendrocytes: 44.5;Other brain neurons: 53.2;Papillary tip epithelial cells: 48.0;Podocytes: 61.9;Proximal tubule cells: 68.2;Renal collecting duct intercalated cells: 64.3;Renal collecting duct principal cells: 54.4;Renal connecting tubule cells: 65.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "HPA037677, HPA037678" Approved Supported Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 39: Testis - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 102: Non-specific - Mixed function" 68 Nucleoplasm "HPA037677: , HPA037678: " "unprognostic (1.32e-1)" "unprognostic (2.62e-1)" "unprognostic (1.62e-1)" "unprognostic (4.00e-2)" "unprognostic (3.55e-1)" "unprognostic (1.77e-1)" "unprognostic (2.59e-1)" "unprognostic (1.96e-1)" "unprognostic (5.62e-3)" "unprognostic (7.31e-3)" "potential prognostic favorable (8.26e-7)" "unprognostic (2.37e-3)" "unprognostic (2.79e-2)" "unprognostic (5.31e-3)" "unprognostic (3.12e-2)" "unprognostic (1.74e-1)" "unprognostic (3.38e-3)" "unprognostic (7.75e-2)" "unprognostic (7.46e-3)" "unprognostic (8.52e-2)" "unprognostic (1.44e-1)" "unprognostic (1.10e-1)" "unprognostic (4.82e-2)" "unprognostic (5.33e-2)" "unprognostic (2.60e-2)" "unprognostic (8.40e-3)" "unprognostic (1.26e-1)" "unprognostic (2.68e-2)" "unprognostic (1.67e-1)" "unprognostic (7.46e-2)" "unprognostic (1.14e-1)" QRICH2 DKFZP434P0316 ENSG00000129646 "Glutamine rich 2" Q9H0J4 17 76274049-76308276 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 21.3" "Cell type enhanced" "Detected in many" "Early spermatids: 52.9;Late primary spermatocytes: 27.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA052219 Enhanced Uncertain "Nucleoplasm,Nuclear membrane,Vesicles" NA NA "Cluster 67: Testis - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" "Nucleoplasm, Nuclear membrane" Vesicles "HPA052219: " "unprognostic (9.85e-2)" "unprognostic (6.88e-2)" "unprognostic (1.39e-1)" "unprognostic (2.27e-1)" "unprognostic (1.04e-1)" "unprognostic (2.76e-1)" "potential prognostic favorable (2.46e-4)" "unprognostic (5.88e-2)" "unprognostic (2.24e-1)" "unprognostic (1.95e-1)" "unprognostic (1.11e-1)" "unprognostic (1.61e-1)" "unprognostic (2.10e-1)" "potential prognostic favorable (1.16e-5)" "unprognostic (2.80e-2)" "unprognostic (2.21e-1)" "unprognostic (3.66e-1)" "unprognostic (1.08e-1)" "unprognostic (1.08e-1)" QRSL1 "DKFZP564C1278, FLJ10989, FLJ12189, FLJ13447, GatA" ENSG00000130348 "Glutaminyl-tRNA amidotransferase subunit QRSL1" Q9H0R6 6 106629578-106668417 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" Ligase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 95.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "memory B-cell: 86.6;naive B-cell: 71.2" "Lineage enriched" "Detected in all" 7 "B-cells: 86.6" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Spleen - B-cells (Spleen), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029585, HPA029587" Approved Approved Vesicles,Centrosome NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 52: Non-specific - Cellular respiration" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 52 Vesicles Centrosome "HPA029585: , HPA029587: " "unprognostic (1.47e-1)" "unprognostic (1.01e-3)" "unprognostic (7.63e-2)" "unprognostic (1.08e-1)" "unprognostic (2.94e-2)" "potential prognostic favorable (5.74e-4)" "unprognostic (2.11e-2)" "unprognostic (5.60e-2)" "unprognostic (1.59e-1)" "unprognostic (1.47e-1)" "potential prognostic favorable (1.01e-6)" "unprognostic (1.08e-2)" "unprognostic (2.27e-3)" "potential prognostic unfavorable (1.50e-4)" "unprognostic (3.62e-3)" "unprognostic (1.34e-1)" "unprognostic (2.13e-1)" "unprognostic (1.10e-1)" "unprognostic (1.07e-1)" "unprognostic (1.76e-1)" "unprognostic (4.98e-3)" "unprognostic (1.44e-1)" "unprognostic (3.78e-3)" "unprognostic (1.56e-1)" "unprognostic (2.79e-3)" "unprognostic (5.04e-2)" "unprognostic (2.02e-1)" "unprognostic (2.35e-1)" "unprognostic (2.58e-1)" "unprognostic (1.58e-1)" "unprognostic (2.53e-1)" QSER1 FLJ21924 ENSG00000060749 "Glutamine and serine rich 1" 11 32892811-32993316 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005682 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 55: Breast - Lactation" "Cluster 25: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 7 Nucleoplasm Cytosol "HPA005682: " "unprognostic (5.48e-1)" "unprognostic (1.11e-1)" "unprognostic (1.52e-1)" "potential prognostic unfavorable (4.46e-4)" "unprognostic (3.31e-2)" "unprognostic (9.41e-2)" "unprognostic (7.22e-2)" "unprognostic (2.16e-2)" "unprognostic (1.05e-1)" "potential prognostic unfavorable (1.75e-4)" "potential prognostic favorable (4.77e-4)" "unprognostic (8.55e-2)" "unprognostic (1.30e-1)" "potential prognostic unfavorable (9.42e-5)" "unprognostic (5.01e-3)" "unprognostic (5.22e-2)" "potential prognostic unfavorable (9.00e-5)" "unprognostic (8.60e-2)" "unprognostic (3.77e-1)" "unprognostic (2.93e-1)" "unprognostic (1.36e-1)" "potential prognostic unfavorable (1.77e-4)" "unprognostic (1.97e-3)" "unprognostic (9.75e-2)" "potential prognostic favorable (7.04e-5)" "unprognostic (1.82e-1)" "unprognostic (9.33e-2)" "unprognostic (5.57e-2)" "unprognostic (1.04e-1)" "unprognostic (2.24e-2)" "unprognostic (2.41e-1)" QSOX1 QSCN6 ENSG00000116260 "Quiescin sulfhydryl oxidase 1" O00391 1 180154869-180204030 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 955.9;Extravillous trophoblasts: 2747.3;Hepatic stellate cells: 574.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056243 Supported "Golgi apparatus,Vesicles" "Secreted to extracellular matrix" Enzyme NA NA 1000000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" "Golgi apparatus" Vesicles "HPA056243: " "unprognostic (2.52e-1)" "unprognostic (1.76e-1)" "unprognostic (1.39e-1)" "unprognostic (2.10e-3)" "unprognostic (2.16e-1)" "unprognostic (6.43e-3)" "unprognostic (2.68e-3)" "unprognostic (3.64e-2)" "unprognostic (1.70e-1)" "unprognostic (2.38e-2)" "validated prognostic unfavorable (8.19e-8)" "validated prognostic unfavorable (7.21e-8)" "unprognostic (1.21e-3)" "unprognostic (6.02e-2)" "unprognostic (2.25e-2)" "unprognostic (6.09e-2)" "unprognostic (9.57e-2)" "unprognostic (1.35e-2)" "unprognostic (3.77e-3)" "unprognostic (5.76e-2)" "unprognostic (1.23e-1)" "unprognostic (7.50e-3)" "unprognostic (1.45e-1)" "unprognostic (1.20e-2)" "unprognostic (3.20e-1)" "unprognostic (1.90e-1)" "unprognostic (2.40e-2)" "unprognostic (1.69e-1)" "unprognostic (5.15e-2)" "unprognostic (5.02e-3)" "unprognostic (4.02e-2)" QSOX2 "DKFZp762A2013, QSCN6L1, SOXN" ENSG00000165661 "Quiescin sulfhydryl oxidase 2" Q6ZRP7 9 136206333-136245812 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gonadotrophs: 53.5;Lactotrophs: 120.7;Somatotrophs: 94.7;Thyrotrophs: 91.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Pituitary gland - Lactotropes, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012716, HPA017280" Uncertain Supported "Nucleoplasm,Golgi apparatus" "Intracellular and membrane" Enzyme NA NA 3100000 "Cluster 64: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 7 "Golgi apparatus" Nucleoplasm "HPA012716: , HPA017280: " "unprognostic (5.59e-2)" "unprognostic (1.09e-2)" "unprognostic (5.53e-2)" "unprognostic (1.08e-2)" "unprognostic (1.67e-2)" "unprognostic (1.81e-2)" "unprognostic (3.93e-2)" "potential prognostic favorable (3.97e-4)" "unprognostic (8.44e-3)" "potential prognostic unfavorable (3.44e-4)" "unprognostic (4.72e-2)" "unprognostic (2.82e-1)" "unprognostic (3.51e-3)" "unprognostic (6.11e-3)" "unprognostic (5.16e-3)" "unprognostic (1.11e-1)" "unprognostic (8.49e-3)" "unprognostic (9.78e-2)" "unprognostic (8.75e-3)" "unprognostic (5.92e-3)" "unprognostic (1.17e-1)" "unprognostic (6.63e-2)" "unprognostic (2.11e-3)" "unprognostic (6.27e-2)" "unprognostic (2.10e-1)" "unprognostic (3.31e-3)" "unprognostic (2.23e-1)" "unprognostic (3.24e-3)" "unprognostic (2.75e-1)" "unprognostic (7.43e-2)" "unprognostic (2.14e-2)" QTRT1 TGT ENSG00000213339 "Queuine tRNA-ribosyltransferase catalytic subunit 1" Q9BXR0 19 10701430-10713437 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "tRNA processing" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 191.8;Enteric stem cells: 280.5;Enteric transient amplifying cells: 240.8;Enterocytes: 216.2;Goblet cells: 173.5;Paneth cells: 255.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042695, HPA048651, HPA049440" Approved Approved Mitochondria NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 70: Non-specific - Protein processing" "Cluster 14: Neurons - Synaptic function" "Cluster 23: Non-specific - Transcription" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 5 Mitochondria "HPA042695: , HPA048651: , HPA049440: " "unprognostic (3.97e-3)" "unprognostic (1.03e-1)" "unprognostic (7.99e-2)" "unprognostic (1.63e-2)" "unprognostic (3.68e-1)" "unprognostic (9.21e-2)" "unprognostic (5.58e-2)" "unprognostic (3.33e-2)" "unprognostic (4.40e-2)" "unprognostic (3.13e-1)" "unprognostic (9.18e-3)" "unprognostic (4.42e-2)" "unprognostic (1.76e-3)" "unprognostic (8.49e-2)" "unprognostic (2.59e-1)" "unprognostic (1.92e-2)" "unprognostic (1.38e-2)" "unprognostic (1.04e-2)" "unprognostic (8.66e-2)" "unprognostic (3.34e-2)" "unprognostic (2.16e-1)" "unprognostic (3.51e-2)" "unprognostic (4.75e-1)" "unprognostic (2.65e-1)" "unprognostic (1.18e-1)" "unprognostic (2.91e-2)" "unprognostic (6.84e-2)" "unprognostic (8.74e-2)" "unprognostic (2.07e-2)" "unprognostic (1.95e-1)" "unprognostic (4.09e-2)" QTRT2 "FLJ12960, QTRTD1" ENSG00000151576 "Queuine tRNA-ribosyltransferase accessory subunit 2" Q9H974 3 114005833-114088422 "Metabolic proteins, Predicted intracellular proteins" "tRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epicardial cells: 84.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036827, HPA036828, HPA070622" Uncertain Approved "Nucleoli,Endoplasmic reticulum,Golgi apparatus,Cytosol" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 63: Non-specific - Protein processing" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 3 "Endoplasmic reticulum" "Nucleoli, Golgi apparatus, Cytosol" "HPA036827: , HPA036828: , HPA070622: " "unprognostic (6.81e-2)" "unprognostic (2.34e-2)" "unprognostic (9.57e-3)" "unprognostic (2.42e-1)" "unprognostic (8.06e-2)" "unprognostic (5.19e-2)" "unprognostic (1.89e-1)" "unprognostic (3.78e-1)" "unprognostic (5.54e-3)" "potential prognostic favorable (3.51e-4)" "unprognostic (9.20e-2)" "unprognostic (1.72e-1)" "potential prognostic unfavorable (2.54e-4)" "unprognostic (1.06e-1)" "unprognostic (4.03e-3)" "unprognostic (5.79e-2)" "unprognostic (1.27e-1)" "unprognostic (2.21e-2)" "unprognostic (8.82e-2)" "potential prognostic unfavorable (6.26e-4)" "unprognostic (1.15e-2)" "unprognostic (2.43e-3)" "unprognostic (3.48e-3)" "unprognostic (1.50e-1)" "unprognostic (8.22e-2)" "unprognostic (3.13e-2)" "unprognostic (1.47e-1)" "unprognostic (1.04e-1)" "unprognostic (4.46e-2)" R3HCC1 DKFZp564N123 ENSG00000104679 "R3H domain and coiled-coil containing 1" Q9Y3T6 8 23270120-23296279 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 177.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023073, HPA023153" Uncertain Approved Nucleoplasm,Cytosol Yes No "Cluster 45: Eosinophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 40: Non-specific - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" 1 Cytosol Nucleoplasm "HPA023073: , HPA023153: " "unprognostic (5.20e-3)" "unprognostic (5.08e-2)" "unprognostic (7.64e-2)" "unprognostic (1.03e-2)" "unprognostic (4.57e-3)" "unprognostic (1.39e-3)" "unprognostic (2.53e-1)" "unprognostic (7.09e-2)" "unprognostic (1.68e-2)" "unprognostic (7.45e-3)" "validated prognostic favorable (3.74e-6)" "validated prognostic favorable (5.43e-4)" "unprognostic (1.56e-2)" "unprognostic (1.48e-2)" "unprognostic (8.22e-2)" "unprognostic (1.04e-1)" "unprognostic (8.01e-2)" "unprognostic (2.51e-1)" "unprognostic (5.85e-2)" "unprognostic (3.30e-1)" "unprognostic (9.84e-2)" "potential prognostic favorable (8.04e-4)" "unprognostic (3.28e-1)" "unprognostic (2.22e-2)" "unprognostic (2.96e-2)" "unprognostic (2.20e-1)" "unprognostic (1.40e-1)" "unprognostic (3.16e-2)" "unprognostic (8.20e-2)" "unprognostic (1.75e-1)" "unprognostic (1.49e-3)" R3HCC1L "C10orf28, GIDRP86, PSORT" ENSG00000166024 "R3H domain and coiled-coil containing 1 like" Q7Z5L2 10 98134624-98244897 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037367 Enhanced Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 39: Testis - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 35: RS4;11 - Unknown function" "Cluster 7: Non-specific - Transcription" 2 "Nucleoplasm, Nuclear speckles" "HPA037367: " "unprognostic (2.52e-1)" "unprognostic (2.03e-1)" "unprognostic (1.56e-1)" "unprognostic (3.35e-3)" "unprognostic (1.33e-1)" "unprognostic (1.61e-1)" "potential prognostic favorable (7.28e-4)" "unprognostic (1.62e-1)" "unprognostic (2.93e-2)" "unprognostic (8.14e-2)" "unprognostic (3.66e-2)" "unprognostic (4.67e-2)" "potential prognostic unfavorable (5.00e-4)" "unprognostic (1.67e-1)" "unprognostic (2.00e-1)" "unprognostic (5.83e-2)" "unprognostic (2.47e-1)" "unprognostic (4.71e-2)" "potential prognostic unfavorable (6.72e-5)" "unprognostic (2.82e-1)" "unprognostic (6.58e-3)" "unprognostic (2.54e-1)" "unprognostic (1.19e-1)" "unprognostic (2.56e-2)" "unprognostic (3.70e-1)" "unprognostic (2.35e-1)" "unprognostic (7.07e-2)" "unprognostic (2.04e-1)" "unprognostic (9.46e-2)" R3HDM1 "KIAA0029, R3HDM" ENSG00000048991 "R3H domain containing 1" Q15032 2 135531455-135725270 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 62.7" "Cell type enhanced" "Detected in all" "Brain excitatory neurons: 626.1;Brain inhibitory neurons: 532.8;Lactotrophs: 481.7;Sertoli cells: 645.7;Somatotrophs: 489.5;Thyrotrophs: 543.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030936 Approved Nucleoplasm,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 35: Neurons - Synaptic function & neurogenesis" 19 "Nucleoplasm, Cytosol" "HPA030936: " "unprognostic (2.35e-1)" "unprognostic (2.79e-2)" "unprognostic (4.29e-1)" "unprognostic (2.30e-1)" "unprognostic (2.11e-2)" "unprognostic (1.27e-1)" "unprognostic (4.29e-2)" "unprognostic (2.04e-1)" "unprognostic (1.65e-1)" "unprognostic (1.50e-2)" "unprognostic (1.61e-2)" "unprognostic (3.64e-1)" "potential prognostic unfavorable (9.89e-5)" "unprognostic (2.27e-3)" "unprognostic (1.41e-3)" "potential prognostic unfavorable (3.93e-5)" "unprognostic (5.50e-3)" "unprognostic (2.80e-2)" "unprognostic (3.75e-2)" "unprognostic (1.82e-1)" "unprognostic (8.64e-2)" "unprognostic (2.64e-2)" "unprognostic (4.11e-2)" "unprognostic (9.25e-2)" "unprognostic (2.82e-2)" "unprognostic (9.33e-2)" "unprognostic (1.86e-2)" "unprognostic (2.98e-1)" "unprognostic (4.34e-2)" "potential prognostic unfavorable (9.06e-5)" "unprognostic (1.79e-1)" R3HDM2 KIAA1002 ENSG00000179912 "R3H domain containing 2" Q9Y2K5 12 57253762-57431043 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Myonuclei: 744.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pituitary gland - Lactotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038327, HPA038328" Approved Supported Nucleoplasm NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 53: Neurons - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 55: Myocytes - Oxidative muscle function" 27 Nucleoplasm "HPA038327: , HPA038328: " "unprognostic (5.29e-2)" "unprognostic (2.43e-2)" "unprognostic (6.10e-2)" "unprognostic (1.42e-1)" "unprognostic (9.66e-2)" "unprognostic (4.59e-2)" "unprognostic (1.95e-1)" "unprognostic (3.32e-1)" "unprognostic (1.81e-1)" "unprognostic (1.11e-2)" "potential prognostic favorable (8.37e-4)" "unprognostic (3.28e-2)" "unprognostic (2.53e-2)" "unprognostic (2.29e-1)" "unprognostic (6.65e-2)" "unprognostic (1.55e-1)" "unprognostic (3.79e-2)" "unprognostic (1.15e-1)" "unprognostic (2.50e-1)" "unprognostic (1.16e-2)" "unprognostic (2.20e-1)" "unprognostic (3.78e-1)" "unprognostic (2.26e-2)" "unprognostic (2.62e-1)" "unprognostic (2.15e-2)" "unprognostic (3.16e-2)" "unprognostic (1.08e-1)" "unprognostic (2.42e-1)" "unprognostic (1.85e-1)" "unprognostic (4.34e-2)" "unprognostic (1.37e-1)" R3HDM4 "C19orf22, MGC16353" ENSG00000198858 "R3H domain containing 4" Q96D70 19 896503-913245 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocytes: 216.4;Esophageal apical cells: 182.2;Megakaryocytes: 142.2;Neutrophils: 604.2;Platelets: 566.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "neutrophil: 589.0" "Lineage enriched" "Detected in all" 12 "granulocytes: 589.0" "Low cancer specificity" "Detected in all" "Liver - Neutrophils, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043025, HPA048638" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 24: Neutrophils - Innate immunity signal integration" Nucleoplasm Cytosol "HPA043025: , HPA048638: " "unprognostic (7.41e-3)" "unprognostic (8.51e-2)" "unprognostic (2.20e-1)" "unprognostic (1.34e-1)" "unprognostic (6.65e-3)" "unprognostic (4.24e-2)" "unprognostic (4.22e-2)" "unprognostic (7.68e-2)" "unprognostic (3.08e-1)" "validated prognostic unfavorable (2.91e-5)" "validated prognostic unfavorable (3.08e-4)" "unprognostic (6.99e-2)" "unprognostic (1.09e-3)" "unprognostic (8.00e-3)" "unprognostic (5.26e-2)" "unprognostic (3.29e-1)" "unprognostic (5.24e-2)" "unprognostic (3.95e-2)" "unprognostic (1.30e-1)" "unprognostic (4.49e-1)" "unprognostic (1.54e-2)" "unprognostic (9.56e-2)" "unprognostic (9.84e-2)" "unprognostic (4.16e-2)" "unprognostic (1.96e-1)" "unprognostic (4.54e-2)" "unprognostic (2.07e-1)" "unprognostic (1.00e-1)" "unprognostic (9.67e-2)" R3HDML dJ881L22.3 ENSG00000101074 "R3H domain containing like" Q9H3Y0 20 44337043-44351238 "Predicted secreted proteins" "Protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 5 "intestine: 2.3" "Cell type enhanced" "Detected in some" "Colonocytes: 3.4;Endometrial ciliated cells: 2.2;Enteric stem cells: 16.4;Enteric transient amplifying cells: 5.7;Enterocytes: 3.6;Fallopian tube ciliated cells: 2.9;Goblet cells: 2.7;Paneth cells: 11.6;Respiratory ciliated cells: 3.2;Tuft cells: 11.5" "Cell type enriched" "Detected in single" 17 "fibroblast: 6.6" "Group enriched" "Detected in some" 6 "Colon Adenocarcinoma (TCGA): 7.2;Rectum Adenocarcinoma (TCGA): 9.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "colorectal cancer: 5.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA062414, HPA070264" Enhanced Approved Nucleoplasm,Cytosol "Secreted - unknown location" "Enzyme inhibitor" NA NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 34: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 1 Cytosol Nucleoplasm "HPA062414: , HPA070264: " "unprognostic (9.05e-2)" "unprognostic (2.12e-1)" "unprognostic (6.03e-3)" "unprognostic (2.64e-2)" "unprognostic (1.15e-2)" RAB10 ENSG00000084733 "RAB10, member RAS oncogene family" P61026 2 26034084-26137454 "Enzymes, Predicted intracellular proteins" "Protein transport, Transport" Hydrolase Neurodegeneration "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 5965.4;Esophageal suprabasal cells: 1548.9;Suprabasal keratinocytes: 1166.4;Urothelial cells: 1471.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Macrophages, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045611 Approved NA Yes 5600000 "Cluster 40: Monocytes - Innate immune response" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 69: Urothelial cells - Basic cellular functions" 39 "HPA045611: " "unprognostic (1.09e-1)" "unprognostic (7.49e-3)" "unprognostic (1.53e-1)" "unprognostic (1.66e-2)" "unprognostic (1.33e-1)" "unprognostic (1.35e-1)" "unprognostic (3.62e-2)" "unprognostic (3.03e-3)" "unprognostic (2.57e-1)" "unprognostic (2.94e-2)" "potential prognostic favorable (6.72e-7)" "unprognostic (1.55e-1)" "potential prognostic unfavorable (7.62e-4)" "validated prognostic unfavorable (2.75e-5)" "validated prognostic unfavorable (8.52e-4)" "potential prognostic unfavorable (4.82e-4)" "unprognostic (9.26e-2)" "unprognostic (3.98e-2)" "unprognostic (9.79e-2)" "unprognostic (1.36e-2)" "unprognostic (3.27e-1)" "potential prognostic unfavorable (4.12e-4)" "unprognostic (2.33e-3)" "unprognostic (1.28e-2)" "unprognostic (1.39e-1)" "unprognostic (8.51e-2)" "unprognostic (1.68e-1)" "unprognostic (2.07e-1)" "unprognostic (2.13e-1)" "unprognostic (1.31e-1)" "unprognostic (3.36e-2)" RAB11A YL8 ENSG00000103769 "RAB11A, member RAS oncogene family" P62491 15 65726054-65891989 "Enzymes, Predicted intracellular proteins" "Cell cycle, Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epicardial cells: 2205.9;Esophageal apical cells: 4604.1;Platelets: 1542.8;Syncytiotrophoblasts: 1451.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013097, HPA051697, HPA060686" Approved Supported "Vesicles,Primary cilium,Centriolar satellite,Basal body,Cytosol,Equatorial segment,Mid piece,Principal piece" No No "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 14: Neurons - Synaptic function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 297 "Vesicles, Centriolar satellite" "Primary cilium, Basal body, Cytosol, Equatorial segment, Mid piece, Principal piece" "CAB013097: , HPA051697: , HPA060686: " "unprognostic (5.90e-2)" "unprognostic (2.37e-3)" "unprognostic (3.32e-1)" "unprognostic (3.02e-1)" "unprognostic (3.60e-1)" "unprognostic (3.28e-1)" "unprognostic (2.00e-1)" "unprognostic (3.37e-2)" "unprognostic (2.99e-2)" "unprognostic (2.68e-2)" "validated prognostic favorable (2.19e-9)" "validated prognostic favorable (1.39e-4)" "unprognostic (1.15e-1)" "unprognostic (1.91e-2)" "potential prognostic unfavorable (1.30e-4)" "unprognostic (1.30e-3)" "unprognostic (5.41e-2)" "unprognostic (5.89e-2)" "unprognostic (2.13e-1)" "unprognostic (1.53e-1)" "unprognostic (1.65e-1)" "potential prognostic unfavorable (1.56e-5)" "unprognostic (5.12e-2)" "unprognostic (1.45e-1)" "unprognostic (5.02e-2)" "unprognostic (2.98e-1)" "unprognostic (3.46e-1)" "unprognostic (2.52e-1)" "unprognostic (2.08e-1)" "unprognostic (3.64e-2)" "unprognostic (3.25e-2)" RAB11B H-YPT3 ENSG00000185236 "RAB11B, member RAS oncogene family" Q15907 19 8389981-8404434 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein transport, Transport" Hydrolase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 249.2;Syncytiotrophoblasts: 244.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" HPA054396 Approved "Vesicles,Primary cilium,Centriolar satellite,Basal body,Cytosol" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 52 "Vesicles, Centriolar satellite" "Primary cilium, Basal body, Cytosol" "HPA054396: " "unprognostic (1.96e-3)" "unprognostic (4.74e-2)" "unprognostic (1.36e-1)" "unprognostic (1.40e-1)" "unprognostic (1.54e-1)" "unprognostic (1.46e-1)" "unprognostic (9.38e-2)" "unprognostic (3.22e-1)" "unprognostic (1.75e-3)" "unprognostic (9.66e-2)" "unprognostic (5.56e-3)" "unprognostic (6.91e-2)" "unprognostic (1.50e-2)" "unprognostic (1.68e-1)" "unprognostic (2.26e-2)" "unprognostic (5.96e-2)" "unprognostic (7.30e-2)" "unprognostic (9.01e-2)" "unprognostic (3.09e-2)" "unprognostic (3.41e-2)" "unprognostic (1.26e-1)" "unprognostic (3.83e-3)" "potential prognostic unfavorable (4.82e-4)" "unprognostic (8.84e-2)" "unprognostic (1.96e-1)" "unprognostic (3.34e-2)" "unprognostic (3.76e-2)" "unprognostic (7.29e-2)" "unprognostic (1.26e-1)" "unprognostic (1.10e-1)" "unprognostic (5.57e-2)" RAB11FIP1 "FLJ22524, FLJ22622, Rab11-FIP1, RCP" ENSG00000156675 "RAB11 family interacting protein 1" Q6WKZ4 8 37858618-37899497 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 3603.6;Endometrial glandular cells: 1877.3;Endometrial luminal cells: 1715.8;Esophageal apical cells: 2111.6;Neutrophils: 1173.8;Pancreatic acinar cells: 2154.0;Urothelial cells: 1558.3" "Group enriched" "Detected in many" 4 "choroid plexus epithelial cell: 153.8;leukocyte: 93.4" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 7 "choroid plexus: 85.3" "Immune cell enhanced" "Detected in all" "neutrophil: 102.1" "Lineage enriched" "Detected in all" 5 "granulocytes: 102.1" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells, Skin - Keratinocyte (granular), Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB017037, HPA023904, HPA024010, HPA025960" Enhanced Enhanced Vesicles No No "Cluster 7: Non-specific - Innate immune response" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 31 Vesicles "CAB017037: , HPA023904: , HPA024010: , HPA025960: " "unprognostic (3.27e-3)" "unprognostic (6.58e-3)" "unprognostic (1.35e-2)" "unprognostic (2.00e-1)" "unprognostic (2.67e-2)" "unprognostic (3.02e-1)" "unprognostic (5.03e-3)" "unprognostic (1.39e-1)" "unprognostic (1.25e-3)" "unprognostic (3.71e-3)" "potential prognostic favorable (6.94e-6)" "unprognostic (3.09e-1)" "unprognostic (1.47e-1)" "unprognostic (2.98e-1)" "unprognostic (2.03e-1)" "unprognostic (1.03e-1)" "unprognostic (1.73e-2)" "unprognostic (7.39e-2)" "unprognostic (6.84e-2)" "unprognostic (3.43e-2)" "unprognostic (3.21e-3)" "unprognostic (7.82e-3)" "unprognostic (7.99e-2)" "unprognostic (2.57e-2)" "unprognostic (1.38e-2)" "unprognostic (6.96e-3)" "unprognostic (2.50e-1)" "unprognostic (1.91e-1)" "unprognostic (3.02e-1)" "unprognostic (1.07e-1)" "unprognostic (3.59e-1)" RAB11FIP2 "KIAA0941, nRip11, Rab11-FIP2" ENSG00000107560 "RAB11 family interacting protein 2" Q7L804 10 118004916-118046941 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal efferent duct absorptive cells: 228.5;Neutrophil progenitors: 182.2;Parietal cells: 327.1;Renal collecting duct principal cells: 200.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037726 Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 22: Epididymis - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 44 Vesicles Nucleoplasm "HPA037726: " "unprognostic (2.82e-2)" "unprognostic (9.57e-2)" "unprognostic (2.54e-1)" "unprognostic (8.25e-3)" "unprognostic (3.06e-2)" "unprognostic (2.63e-3)" "unprognostic (1.37e-2)" "unprognostic (6.85e-2)" "unprognostic (1.98e-1)" "unprognostic (5.14e-2)" "validated prognostic favorable (4.12e-6)" "validated prognostic favorable (9.03e-4)" "unprognostic (5.22e-2)" "unprognostic (7.64e-2)" "unprognostic (5.33e-2)" "unprognostic (1.84e-1)" "unprognostic (1.31e-1)" "unprognostic (8.82e-2)" "unprognostic (5.01e-2)" "unprognostic (2.49e-1)" "unprognostic (8.49e-2)" "unprognostic (9.16e-2)" "unprognostic (1.88e-1)" "unprognostic (2.19e-1)" "unprognostic (2.19e-1)" "unprognostic (8.22e-3)" "unprognostic (2.30e-2)" "unprognostic (5.35e-2)" "unprognostic (2.35e-1)" "unprognostic (1.13e-1)" "unprognostic (9.09e-2)" RAB11FIP3 "eferin, KIAA0665, Rab11-FIP3" ENSG00000090565 "RAB11 family interacting protein 3" O75154 16 425649-523011 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 151.2" "Cell type enriched" "Detected in many" 7 "Proximal tubule cells: 1639.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028088, HPA028631, HPA030086" Enhanced Supported "Vesicles,Cytokinetic bridge,Primary cilium,Centriolar satellite,Basal body" Yes No "Cluster 72: Kidney - Transmembrane transport" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 88: Proximal tubular cells - Transmembrane transport" 8 "Vesicles, Centriolar satellite, Basal body" "Cytokinetic bridge, Primary cilium" "HPA028088: , HPA028631: , HPA030086: " "unprognostic (3.50e-3)" "unprognostic (9.69e-2)" "unprognostic (8.69e-2)" "unprognostic (1.37e-1)" "unprognostic (8.75e-2)" "unprognostic (3.41e-1)" "unprognostic (5.39e-2)" "unprognostic (2.82e-2)" "unprognostic (1.38e-1)" "unprognostic (1.18e-2)" "validated prognostic favorable (6.84e-5)" "validated prognostic favorable (4.76e-4)" "unprognostic (2.20e-2)" "potential prognostic unfavorable (1.69e-5)" "unprognostic (1.06e-1)" "unprognostic (7.99e-2)" "unprognostic (2.19e-1)" "unprognostic (7.29e-2)" "unprognostic (2.61e-2)" "unprognostic (1.17e-1)" "unprognostic (4.44e-2)" "unprognostic (2.95e-3)" "unprognostic (6.96e-2)" "unprognostic (3.34e-1)" "unprognostic (4.18e-2)" "unprognostic (1.28e-2)" "unprognostic (3.12e-2)" "unprognostic (4.10e-2)" "unprognostic (1.96e-1)" "unprognostic (3.15e-1)" "unprognostic (1.71e-1)" RAB11FIP4 "FLJ00131, KIAA1821, MGC11316, RAB11-FIP4" ENSG00000131242 "RAB11 family interacting protein 4" Q86YS3 17 31391675-31538211 "Predicted intracellular proteins" "Host-virus interaction, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 52.7;testis: 47.0" "Cell type enriched" "Detected in many" 4 "Late spermatids: 2009.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 78.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 78.8" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - T-cells, Breast - Breast glandular cells, Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Minor Salivary Gland - Minor salivary glandular cells, Skin - Keratinocyte (granular), Spleen - B-cells (Spleen), Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063203 Approved Approved "Golgi apparatus,Vesicles,Connecting piece,Mid piece,Principal piece" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 34: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 5 "Golgi apparatus, Vesicles, Connecting piece, Mid piece" "Principal piece" "HPA063203: " "unprognostic (7.77e-2)" "unprognostic (7.04e-2)" "unprognostic (7.71e-2)" "unprognostic (2.34e-2)" "potential prognostic favorable (8.74e-4)" "unprognostic (2.17e-2)" "unprognostic (2.74e-2)" "unprognostic (5.27e-2)" "potential prognostic favorable (1.77e-4)" "unprognostic (7.39e-2)" "potential prognostic favorable (6.82e-8)" "unprognostic (2.71e-2)" "unprognostic (2.44e-1)" "unprognostic (1.58e-1)" "potential prognostic unfavorable (6.29e-5)" "unprognostic (3.23e-2)" "unprognostic (1.40e-1)" "unprognostic (1.96e-1)" "unprognostic (1.22e-1)" "unprognostic (3.55e-2)" "unprognostic (3.83e-2)" "unprognostic (7.75e-2)" "unprognostic (1.89e-1)" "unprognostic (1.21e-1)" "unprognostic (2.57e-3)" "unprognostic (1.11e-2)" "unprognostic (2.36e-1)" "unprognostic (2.13e-2)" "unprognostic (2.45e-1)" "unprognostic (3.93e-1)" "unprognostic (1.21e-1)" RAB11FIP5 "GAF1, KIAA0857, pp75, RIP11" ENSG00000135631 "RAB11 family interacting protein 5" Q9BXF6 2 73073382-73156721 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 35.0" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 39.5;Proximal tubule cells: 33.6;Renal connecting tubule cells: 48.6;Retinal ganglion cells: 57.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Spleen - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036406, HPA036407" Enhanced Approved "Vesicles,Primary cilium,Centriolar satellite,Basal body,Acrosome,Principal piece,End piece,Annulus" NA NA "Cluster 27: T-cells - Unknown function" "Cluster 23: Testis - Spermatogenesis" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 72: Neuronal - Signal transduction" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 28 "Vesicles, Centriolar satellite, Basal body" "Primary cilium, Acrosome, Principal piece, End piece, Annulus" "HPA036406: , HPA036407: " "unprognostic (8.09e-2)" "unprognostic (1.42e-1)" "unprognostic (2.12e-3)" "potential prognostic unfavorable (4.35e-4)" "unprognostic (1.69e-1)" "unprognostic (1.76e-2)" "unprognostic (1.91e-2)" "unprognostic (4.12e-3)" "unprognostic (2.04e-1)" "unprognostic (5.92e-1)" "potential prognostic favorable (2.54e-8)" "unprognostic (1.23e-2)" "unprognostic (1.28e-1)" "unprognostic (2.26e-2)" "unprognostic (1.46e-2)" "unprognostic (8.29e-2)" "unprognostic (2.91e-2)" "unprognostic (3.50e-3)" "unprognostic (6.08e-2)" "validated prognostic unfavorable (3.00e-4)" "validated prognostic unfavorable (6.55e-5)" "unprognostic (2.18e-3)" "unprognostic (2.76e-1)" "unprognostic (2.25e-1)" "unprognostic (1.30e-1)" "unprognostic (1.77e-2)" "unprognostic (2.60e-1)" "unprognostic (1.45e-2)" "unprognostic (4.37e-1)" "unprognostic (1.50e-2)" "potential prognostic unfavorable (9.55e-4)" RAB12 ENSG00000206418 "RAB12, member RAS oncogene family" 18 8609437-8639383 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "skeletal muscle: 180.3" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Minor Salivary Gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040727 Approved Approved Vesicles NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 14: Neurons - Synaptic function" "Cluster 13: Non-specific - Mixed function" "Cluster 82: Dendritic cells - Antigen presentation" 7 Vesicles "HPA040727: " "unprognostic (3.21e-2)" "unprognostic (2.37e-2)" "unprognostic (2.71e-1)" "unprognostic (1.52e-1)" "unprognostic (1.56e-1)" "unprognostic (5.16e-3)" "unprognostic (2.55e-2)" "unprognostic (2.40e-1)" "unprognostic (9.91e-3)" "unprognostic (2.44e-2)" "unprognostic (2.00e-3)" "unprognostic (6.18e-3)" "unprognostic (8.31e-2)" "unprognostic (1.25e-3)" "unprognostic (2.41e-2)" "unprognostic (1.50e-2)" "unprognostic (3.00e-1)" "unprognostic (9.44e-2)" "unprognostic (1.90e-1)" "unprognostic (4.09e-2)" "unprognostic (8.22e-2)" "unprognostic (5.58e-2)" "unprognostic (8.00e-3)" "unprognostic (5.84e-2)" "unprognostic (2.98e-1)" "unprognostic (3.27e-1)" "unprognostic (1.20e-1)" "unprognostic (5.73e-2)" "unprognostic (8.61e-2)" "unprognostic (1.52e-1)" "unprognostic (3.78e-2)" RAB13 ENSG00000143545 "RAB13, member RAS oncogene family" P51153 1 153981617-153986358 "Predicted intracellular proteins" "Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 10.1;Gastric chief cells: 10.9;Loop of henle epithelial cells: 16.5;Papillary tip epithelial cells: 25.7;Renal collecting duct intercalated cells: 10.2;Renal collecting duct principal cells: 24.5;Renal connecting tubule cells: 8.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "classical monocyte: 7.0;myeloid DC: 10.5;plasmacytoid DC: 12.9" "Group enriched" "Detected in many" 11 "dendritic cells: 12.9;monocytes: 7.0" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells, Pituitary gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003996 Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 44: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 30 "Plasma membrane, Cytosol" "HPA003996: " "unprognostic (3.62e-3)" "unprognostic (2.20e-2)" "potential prognostic favorable (7.81e-4)" "unprognostic (5.06e-2)" "unprognostic (1.33e-1)" "unprognostic (1.27e-1)" "unprognostic (2.92e-2)" "unprognostic (5.49e-2)" "unprognostic (1.34e-2)" "unprognostic (2.89e-2)" "unprognostic (3.82e-1)" "unprognostic (9.91e-2)" "unprognostic (5.59e-2)" "potential prognostic unfavorable (1.98e-4)" "unprognostic (4.47e-3)" "potential prognostic unfavorable (5.01e-4)" "unprognostic (7.03e-2)" "unprognostic (1.18e-1)" "unprognostic (1.75e-2)" "unprognostic (2.14e-1)" "unprognostic (6.19e-2)" "unprognostic (1.42e-1)" "unprognostic (6.58e-2)" "unprognostic (2.40e-1)" "unprognostic (9.07e-3)" "unprognostic (2.62e-1)" "unprognostic (1.80e-1)" "unprognostic (6.37e-2)" "unprognostic (1.32e-1)" "unprognostic (1.75e-1)" "unprognostic (2.19e-1)" RAB14 "FBP, RAB-14" ENSG00000119396 "RAB14, member RAS oncogene family" P61106 9 121178133-121223014 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026419, CAB037066" Approved Supported Vesicles NA NA 4100000 "Cluster 40: Monocytes - Innate immune response" "Cluster 76: Non-specific - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 17: Non-specific - RNA processing" 83 Vesicles "CAB037066: , HPA026419: " "unprognostic (1.48e-1)" "unprognostic (1.27e-2)" "unprognostic (3.98e-1)" "unprognostic (9.46e-2)" "unprognostic (1.80e-1)" "potential prognostic unfavorable (3.67e-4)" "unprognostic (2.44e-1)" "unprognostic (1.33e-1)" "unprognostic (3.00e-1)" "unprognostic (3.22e-1)" "validated prognostic favorable (1.12e-7)" "validated prognostic favorable (4.03e-4)" "unprognostic (2.15e-2)" "unprognostic (6.87e-2)" "unprognostic (4.59e-1)" "unprognostic (4.36e-2)" "unprognostic (5.29e-2)" "unprognostic (7.84e-2)" "unprognostic (1.01e-1)" "unprognostic (2.80e-2)" "unprognostic (1.56e-2)" "unprognostic (1.58e-2)" "unprognostic (1.12e-1)" "unprognostic (5.50e-2)" "unprognostic (4.75e-2)" "unprognostic (1.02e-1)" "unprognostic (7.57e-2)" "unprognostic (3.13e-2)" "unprognostic (1.78e-1)" "unprognostic (1.47e-1)" "unprognostic (3.93e-2)" RAB15 ENSG00000139998 "RAB15, member RAS oncogene family" P59190 14 64945814-64973226 "Predicted intracellular proteins" "Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 77.9" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 48.7;Conjunctival goblet cells: 57.3;Prostatic club cells: 45.5;Prostatic hillock cells: 45.3;Salivary duct cells: 140.0;Urothelial cells: 47.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 158.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "plasmacytoid DC: 1.7" "Lineage enriched" "Detected in single" 5 "dendritic cells: 1.7" "Low cancer specificity" "Detected in all" "Prostate - Urothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041177 Uncertain Approved "Vesicles,Centriolar satellite" NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 27: Cerebellum - Synaptic function" "Cluster 51: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 35: Neurons - Synaptic function & neurogenesis" 2 "Vesicles, Centriolar satellite" "HPA041177: " "unprognostic (7.17e-3)" "unprognostic (4.74e-2)" "unprognostic (2.73e-2)" "unprognostic (2.76e-2)" "unprognostic (1.84e-1)" "unprognostic (2.27e-2)" "unprognostic (1.59e-1)" "unprognostic (1.97e-3)" "unprognostic (1.90e-1)" "unprognostic (4.26e-1)" "unprognostic (3.01e-2)" "unprognostic (1.68e-2)" "unprognostic (1.08e-2)" "validated prognostic unfavorable (7.51e-5)" "validated prognostic unfavorable (1.17e-4)" "unprognostic (1.75e-2)" "unprognostic (2.63e-1)" "unprognostic (1.68e-1)" "unprognostic (3.09e-2)" "unprognostic (8.23e-2)" "unprognostic (3.34e-1)" "unprognostic (2.76e-2)" "unprognostic (1.84e-1)" "unprognostic (3.62e-2)" "unprognostic (6.13e-2)" "unprognostic (6.54e-3)" "unprognostic (3.30e-1)" "unprognostic (1.47e-3)" "unprognostic (1.94e-1)" "unprognostic (2.46e-2)" "unprognostic (2.28e-1)" RAB17 ENSG00000124839 "RAB17, member RAS oncogene family" Q9H0T7 2 237574322-237601614 "Predicted intracellular proteins" "Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 72.0;intestine: 72.1;kidney: 77.4;liver: 123.1" "Cell type enhanced" "Detected in many" "Cholangiocytes: 81.0;Cone photoreceptor cells: 113.9;Enterocytes: 231.9;Epididymal efferent duct absorptive cells: 107.6;Epididymal principal cells: 78.3;Hepatocytes: 167.1;Parietal cells: 106.1" "Cell type enriched" "Detected in many" 16 "choroid plexus epithelial cell: 68.7" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 14 "choroid plexus: 54.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Breast - Breast glandular cells, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA035176 Approved Approved Vesicles NA NA "Cluster 77: Intestine - Digestion" "Cluster 36: Choroid plexus - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 93: Hepatocytes - Bile production & excretion" 4 Vesicles "HPA035176: " "unprognostic (1.01e-1)" "unprognostic (2.15e-1)" "unprognostic (2.75e-1)" "unprognostic (2.45e-1)" "unprognostic (5.62e-2)" "unprognostic (1.32e-3)" "unprognostic (6.11e-2)" "unprognostic (3.09e-2)" "validated prognostic favorable (3.96e-8)" "validated prognostic favorable (8.81e-6)" "potential prognostic favorable (1.94e-6)" "unprognostic (2.33e-1)" "unprognostic (5.77e-2)" "unprognostic (2.39e-2)" "unprognostic (1.07e-1)" "unprognostic (3.98e-3)" "unprognostic (1.45e-1)" "unprognostic (7.63e-2)" "unprognostic (2.65e-1)" "potential prognostic favorable (3.41e-5)" "unprognostic (6.54e-2)" "unprognostic (2.71e-1)" "unprognostic (1.43e-1)" "unprognostic (9.15e-2)" "unprognostic (1.22e-3)" "unprognostic (3.02e-2)" "unprognostic (1.17e-1)" "unprognostic (1.43e-1)" "unprognostic (3.57e-1)" RAB18 ENSG00000099246 "RAB18, member RAS oncogene family" Q9NP72 10 27504174-27543207 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction, Protein transport, Transport" "Developmental protein, Hydrolase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Breast lactating cells: 654.1;Esophageal apical cells: 656.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025928 Uncertain NA NA 70000 "Cluster 35: Neutrophils - Protein binding" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 52: Non-specific - Mitochondria" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 37 "HPA025928: " "unprognostic (1.04e-1)" "unprognostic (6.32e-3)" "unprognostic (8.46e-3)" "unprognostic (5.49e-2)" "unprognostic (1.93e-1)" "unprognostic (2.02e-2)" "unprognostic (1.11e-1)" "potential prognostic favorable (1.87e-4)" "unprognostic (6.62e-2)" "unprognostic (9.11e-3)" "potential prognostic favorable (6.43e-8)" "unprognostic (1.09e-3)" "unprognostic (3.38e-1)" "unprognostic (3.88e-2)" "unprognostic (2.88e-2)" "unprognostic (2.36e-1)" "unprognostic (3.70e-2)" "unprognostic (4.92e-1)" "unprognostic (2.17e-1)" "unprognostic (2.20e-2)" "unprognostic (1.89e-2)" "unprognostic (1.09e-1)" "unprognostic (2.39e-1)" "unprognostic (3.74e-1)" "unprognostic (1.34e-1)" "unprognostic (2.79e-1)" "unprognostic (2.27e-1)" "unprognostic (1.49e-1)" "unprognostic (2.92e-1)" "unprognostic (1.40e-1)" "unprognostic (3.44e-1)" RAB19 RAB19B ENSG00000146955 "RAB19, member RAS oncogene family" A4D1S5 7 140404058-140427974 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 3.5" "Cell type enhanced" "Detected in many" "Foveolar cells: 13.0;Neutrophil progenitors: 57.6;Neutrophils: 20.5;Tuft cells: 11.5" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Colon - Colon enterocytes, Minor Salivary Gland - Minor salivary glandular cells, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA051077 Uncertain NA NA "Cluster 11: T-cells - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 3 "HPA051077: " "unprognostic (8.69e-2)" "unprognostic (2.13e-1)" "unprognostic (9.51e-2)" "unprognostic (4.88e-2)" "unprognostic (9.90e-2)" "unprognostic (3.93e-2)" "unprognostic (2.66e-1)" "potential prognostic favorable (8.56e-4)" "unprognostic (2.32e-2)" "potential prognostic favorable (6.62e-5)" "unprognostic (1.20e-2)" "unprognostic (2.11e-1)" "unprognostic (1.38e-1)" "unprognostic (2.20e-1)" "unprognostic (1.42e-1)" "unprognostic (2.27e-2)" "unprognostic (2.97e-1)" "unprognostic (2.11e-1)" "unprognostic (2.25e-1)" "unprognostic (2.54e-2)" "unprognostic (2.27e-3)" "unprognostic (7.19e-2)" "unprognostic (2.95e-1)" "unprognostic (3.00e-2)" RAB1A "RAB1, YPT1" ENSG00000138069 "RAB1A, member RAS oncogene family" P62820 2 65070696-65130331 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Autophagy, ER-Golgi transport, Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1046.6;Late spermatids: 1610.3;Neutrophils: 2120.8;Syncytiotrophoblasts: 1104.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005331, HPA056141" Approved Supported "Endoplasmic reticulum,Cytosol" NA NA 7200000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 107 "Endoplasmic reticulum, Cytosol" "CAB005331: , HPA056141: " "unprognostic (6.39e-2)" "unprognostic (3.29e-3)" "unprognostic (2.58e-1)" "potential prognostic unfavorable (4.73e-4)" "unprognostic (1.11e-2)" "unprognostic (7.82e-3)" "potential prognostic unfavorable (5.29e-4)" "unprognostic (3.33e-3)" "unprognostic (9.87e-3)" "unprognostic (5.91e-3)" "unprognostic (1.64e-3)" "unprognostic (3.12e-1)" "unprognostic (6.07e-2)" "unprognostic (2.23e-3)" "potential prognostic unfavorable (6.61e-5)" "unprognostic (5.57e-3)" "unprognostic (2.30e-2)" "unprognostic (1.18e-1)" "unprognostic (3.12e-2)" "unprognostic (7.74e-2)" "unprognostic (2.99e-2)" "unprognostic (5.73e-3)" "unprognostic (7.96e-3)" "unprognostic (1.85e-1)" "unprognostic (5.48e-1)" "unprognostic (7.37e-2)" "unprognostic (7.14e-2)" "unprognostic (1.79e-1)" "unprognostic (1.35e-1)" "unprognostic (9.44e-2)" "unprognostic (2.05e-1)" RAB1B ENSG00000174903 "RAB1B, member RAS oncogene family" Q9H0U4 11 66268590-66277492 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Autophagy, Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 212.5;Platelets: 410.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Prostate glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010225, HPA056141" Approved Supported "Endoplasmic reticulum,Golgi apparatus" NA NA 8800000 "Cluster 7: Non-specific - Innate immune response" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 47: Platelets - Hemostasis" 64 "Golgi apparatus" "Endoplasmic reticulum" "CAB010225: , HPA056141: " "unprognostic (1.06e-2)" "unprognostic (4.54e-2)" "unprognostic (5.09e-2)" "unprognostic (7.88e-3)" "unprognostic (9.94e-2)" "unprognostic (1.52e-2)" "unprognostic (4.01e-2)" "unprognostic (1.15e-1)" "unprognostic (1.33e-1)" "unprognostic (8.58e-3)" "potential prognostic favorable (1.02e-4)" "unprognostic (6.91e-2)" "unprognostic (6.45e-3)" "unprognostic (5.43e-3)" "unprognostic (4.80e-2)" "unprognostic (2.29e-3)" "potential prognostic unfavorable (7.27e-4)" "unprognostic (1.41e-2)" "unprognostic (6.02e-2)" "unprognostic (1.86e-2)" "unprognostic (2.39e-1)" "unprognostic (3.14e-2)" "unprognostic (1.14e-1)" "unprognostic (1.15e-1)" "unprognostic (2.97e-1)" "unprognostic (1.15e-1)" "unprognostic (3.17e-1)" "unprognostic (1.34e-1)" "unprognostic (1.72e-1)" "unprognostic (8.01e-2)" "unprognostic (1.70e-1)" RAB20 FLJ20429 ENSG00000139832 "RAB20, member RAS oncogene family" Q9NX57 13 110523066-110561722 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 143.9;Hofbauer cells: 270.2;Kupffer cells: 411.0;Macrophages: 251.3;monocytes: 331.3;Neutrophils: 421.2" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 66.9;vascular associated smooth muscle cell: 23.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Kidney - Macrophages, Liver - Neutrophils, Spleen - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA002882, HPA052111, HPA068647" Uncertain Supported "Golgi apparatus,Vesicles" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 28: Liver & Adrenal gland - Secretion" "Cluster 12: Non-specific - Vasculature" "Cluster 19: Non-specific - Unknown function" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 4 Vesicles "Golgi apparatus" "HPA002882: , HPA052111: , HPA068647: " "unprognostic (1.08e-2)" "unprognostic (1.12e-2)" "unprognostic (1.78e-1)" "unprognostic (2.19e-1)" "unprognostic (1.85e-1)" "unprognostic (1.76e-2)" "unprognostic (6.31e-2)" "unprognostic (2.13e-1)" "unprognostic (3.34e-2)" "unprognostic (1.97e-1)" "potential prognostic favorable (4.30e-4)" "unprognostic (7.95e-3)" "potential prognostic favorable (1.56e-4)" "unprognostic (2.87e-3)" "unprognostic (9.89e-2)" "unprognostic (7.64e-2)" "unprognostic (2.42e-1)" "unprognostic (2.09e-2)" "unprognostic (3.84e-2)" "unprognostic (4.98e-3)" "unprognostic (7.80e-2)" "unprognostic (1.36e-1)" "unprognostic (8.59e-2)" "unprognostic (3.71e-1)" "unprognostic (6.62e-2)" "unprognostic (1.84e-2)" "unprognostic (2.07e-1)" "unprognostic (3.62e-1)" "unprognostic (3.95e-2)" "unprognostic (1.82e-1)" "unprognostic (3.08e-2)" RAB21 KIAA0118 ENSG00000080371 "RAB21, member RAS oncogene family" Q9UL25 12 71754863-71800286 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 645.0;Late spermatids: 1002.7;Neutrophils: 766.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016988, CAB037048" Approved NA NA 49000 "Cluster 35: Neutrophils - Protein binding" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 29 "CAB037048: , HPA016988: " "unprognostic (3.70e-2)" "unprognostic (1.38e-2)" "unprognostic (4.63e-1)" "unprognostic (3.76e-1)" "unprognostic (7.08e-2)" "unprognostic (6.77e-3)" "unprognostic (2.48e-1)" "unprognostic (1.36e-1)" "unprognostic (3.74e-2)" "unprognostic (4.54e-2)" "validated prognostic favorable (2.69e-8)" "validated prognostic favorable (3.67e-4)" "unprognostic (3.81e-3)" "unprognostic (3.63e-2)" "unprognostic (1.05e-2)" "unprognostic (9.93e-3)" "unprognostic (1.31e-1)" "unprognostic (5.73e-2)" "unprognostic (1.86e-1)" "unprognostic (5.68e-2)" "unprognostic (2.46e-2)" "unprognostic (3.91e-2)" "unprognostic (1.06e-1)" "unprognostic (1.69e-2)" "unprognostic (9.53e-3)" "unprognostic (3.09e-1)" "unprognostic (1.15e-1)" "unprognostic (1.62e-1)" "unprognostic (1.85e-1)" "unprognostic (1.25e-1)" "unprognostic (9.11e-2)" RAB22A ENSG00000124209 "RAB22A, member RAS oncogene family" Q9UL26 20 58309715-58367507 "Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 311.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066920, HPA074046" Approved Supported "Golgi apparatus,Vesicles" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 73: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 85: Squamous epithelial cells - Keratinization" 11 "Golgi apparatus, Vesicles" "HPA066920: , HPA074046: " "unprognostic (2.86e-2)" "unprognostic (1.43e-2)" "unprognostic (2.16e-1)" "unprognostic (4.94e-2)" "unprognostic (4.71e-1)" "unprognostic (3.94e-2)" "unprognostic (1.45e-1)" "unprognostic (4.21e-3)" "unprognostic (1.34e-1)" "unprognostic (1.14e-2)" "unprognostic (3.07e-2)" "unprognostic (2.70e-1)" "unprognostic (3.68e-1)" "potential prognostic unfavorable (7.67e-4)" "unprognostic (6.54e-2)" "unprognostic (1.84e-1)" "unprognostic (5.89e-3)" "unprognostic (1.33e-1)" "unprognostic (1.49e-1)" "unprognostic (6.51e-2)" "unprognostic (7.40e-3)" "unprognostic (6.09e-3)" "unprognostic (1.52e-2)" "unprognostic (1.24e-2)" "unprognostic (2.08e-1)" "unprognostic (2.26e-2)" "unprognostic (2.91e-1)" "unprognostic (1.38e-1)" "unprognostic (3.15e-2)" "unprognostic (4.40e-3)" "unprognostic (8.46e-2)" RAB23 ENSG00000112210 "RAB23, member RAS oncogene family" Q9ULC3 6 57186992-57222307 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Developmental protein, Hydrolase" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 42.9;Retinal pigment epithelial cells: 42.6;Smooth muscle cells: 106.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029135, HPA029136" Enhanced Supported "Plasma membrane,Primary cilium,Centrosome,Basal body,Cytosol" NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 55: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 62: Smooth muscle cells - Muscle contraction" 8 "Plasma membrane, Cytosol" "Primary cilium, Centrosome, Basal body" "HPA029135: , HPA029136: " "unprognostic (1.83e-3)" "unprognostic (8.57e-2)" "unprognostic (1.84e-2)" "unprognostic (2.05e-1)" "unprognostic (2.06e-1)" "unprognostic (8.28e-2)" "unprognostic (2.01e-2)" "unprognostic (2.78e-1)" "unprognostic (3.70e-2)" "unprognostic (1.12e-3)" "unprognostic (1.65e-2)" "unprognostic (4.84e-2)" "unprognostic (1.16e-3)" "unprognostic (1.78e-2)" "potential prognostic unfavorable (4.91e-6)" "unprognostic (4.11e-3)" "unprognostic (8.55e-2)" "unprognostic (1.64e-1)" "unprognostic (3.22e-1)" "unprognostic (8.65e-2)" "unprognostic (1.21e-2)" "unprognostic (1.61e-1)" "unprognostic (1.69e-1)" "unprognostic (1.23e-2)" "unprognostic (4.40e-1)" "unprognostic (3.17e-2)" "unprognostic (9.13e-2)" "unprognostic (1.28e-2)" "unprognostic (2.49e-1)" "unprognostic (4.67e-2)" "unprognostic (1.81e-2)" RAB24 ENSG00000169228 "RAB24, member RAS oncogene family" Q969Q5 5 177301198-177303744 "Predicted intracellular proteins" "Autophagy, Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 31.8;Bergmann glia: 28.8;Brain excitatory neurons: 35.5;Brain inhibitory neurons: 33.3;Epididymal principal cells: 30.0;Esophageal apical cells: 29.7;Other brain neurons: 33.8;Syncytiotrophoblasts: 40.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078320 Supported Cytosol NA No "Cluster 7: Non-specific - Innate immune response" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 24: Neurons - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 98: Neurons - Neurotransmission & signaling" 20 Cytosol "HPA078320: " "unprognostic (1.04e-1)" "unprognostic (1.62e-1)" "unprognostic (1.84e-2)" "unprognostic (2.64e-1)" "unprognostic (1.47e-1)" "unprognostic (1.52e-1)" "potential prognostic unfavorable (1.04e-4)" "unprognostic (1.56e-2)" "unprognostic (2.72e-3)" "unprognostic (3.47e-2)" "unprognostic (1.68e-3)" "unprognostic (6.58e-2)" "unprognostic (1.54e-1)" "potential prognostic unfavorable (6.70e-5)" "unprognostic (2.01e-1)" "unprognostic (2.76e-1)" "unprognostic (2.59e-1)" "unprognostic (2.04e-1)" "unprognostic (2.83e-1)" "unprognostic (2.55e-1)" "unprognostic (3.20e-1)" "unprognostic (2.13e-3)" "potential prognostic unfavorable (3.75e-4)" "unprognostic (3.53e-1)" "unprognostic (4.40e-2)" "unprognostic (4.73e-3)" "unprognostic (5.27e-2)" "unprognostic (1.09e-1)" "unprognostic (1.17e-1)" "unprognostic (1.53e-1)" "unprognostic (1.86e-1)" RAB25 CATX-8 ENSG00000132698 "RAB25, member RAS oncogene family" P57735 1 156061160-156070504 "Cancer-related genes, Predicted intracellular proteins" "Protein transport, Transport" Hydrolase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 407.1;skin 1: 203.2" "Group enriched" "Detected in many" 7 "Esophageal apical cells: 3926.5;Esophageal suprabasal cells: 1503.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 1.3;naive CD4 T-cell: 1.2" "Lineage enriched" "Detected in single" 13 "T-cells: 1.3" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Colon - Colon enterocytes, Liver - Cholangiocytes, Lung - Alveolar cells type 2, Skin - Keratinocyte (other), Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA010940, CAB033645" Enhanced Supported "Plasma membrane" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 17 "Plasma membrane" "CAB033645: , HPA010940: " "unprognostic (1.60e-1)" "unprognostic (6.48e-2)" "unprognostic (3.83e-1)" "unprognostic (1.74e-1)" "unprognostic (4.56e-2)" "unprognostic (1.10e-1)" "unprognostic (2.74e-1)" "unprognostic (2.38e-1)" "unprognostic (2.83e-2)" "unprognostic (2.10e-2)" "unprognostic (1.59e-1)" "unprognostic (3.91e-1)" "unprognostic (1.48e-1)" "unprognostic (2.73e-1)" "unprognostic (3.33e-1)" "unprognostic (1.89e-1)" "unprognostic (1.25e-1)" "unprognostic (2.17e-2)" "unprognostic (1.54e-1)" "unprognostic (5.75e-3)" "unprognostic (3.74e-2)" "unprognostic (5.00e-2)" "unprognostic (5.88e-2)" "unprognostic (2.38e-3)" "unprognostic (1.13e-1)" "unprognostic (6.14e-3)" "unprognostic (2.08e-1)" "unprognostic (2.55e-1)" "unprognostic (8.21e-2)" RAB26 ENSG00000167964 "RAB26, member RAS oncogene family" Q9ULW5 16 2140803-2154165 "Predicted intracellular proteins" "Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 116.2;liver: 51.4;pancreas: 41.6" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 123.1;Colonocytes: 197.2;Enterocytes: 126.7;Epididymal basal cells: 102.4;Goblet cells: 170.4;Neuroendocrine cells: 124.8;Paneth cells: 247.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 17.2" "Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Skeletal myocytes, Stomach - Chief cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075624 Uncertain "Vesicles,Plasma membrane,Cell Junctions,Centrosome,Cytosol" No No "Cluster 27: Cerebellum - Synaptic function" "Cluster 51: Neurons - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 65: Non-specific - Cell growth & division" 8 "Plasma membrane, Centrosome" "Vesicles, Cell Junctions, Cytosol" "HPA075624: " "unprognostic (4.08e-2)" "unprognostic (2.15e-2)" "unprognostic (1.73e-1)" "unprognostic (1.03e-3)" "unprognostic (4.62e-2)" "unprognostic (8.65e-3)" "unprognostic (1.66e-1)" "unprognostic (7.08e-2)" "unprognostic (1.13e-1)" "unprognostic (1.34e-2)" "unprognostic (9.52e-2)" "unprognostic (3.85e-2)" "potential prognostic favorable (9.10e-6)" "unprognostic (7.71e-2)" "unprognostic (1.40e-2)" "unprognostic (9.68e-2)" "unprognostic (1.51e-1)" "unprognostic (8.28e-2)" "unprognostic (2.34e-1)" "unprognostic (4.01e-2)" "unprognostic (2.99e-1)" "unprognostic (2.67e-1)" "unprognostic (1.85e-1)" "unprognostic (2.75e-2)" "unprognostic (4.29e-2)" "unprognostic (5.12e-2)" "unprognostic (2.23e-2)" "unprognostic (1.86e-2)" RAB27A "GS2, HsT18676, RAB27, RAM" ENSG00000069974 "RAB27A, member RAS oncogene family" P51159 15 55202966-55319113 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Exocytosis Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "stomach 1: 114.2" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 417.3;Foveolar cells: 312.8;Goblet cells: 376.3;Neutrophil progenitors: 1540.7;Neutrophils: 1394.0" "Cell type enhanced" "Detected in all" "leukocyte: 257.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 262.4" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "skin cancer: 102.5" "Kidney - Endothelial cells, Prostate - Prostate glandular cells, Skeletal muscle - Endothelial cells, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001333, CAB034046" Enhanced Approved "Mid piece,Principal piece" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 17: Intestine - Digestion" "Cluster 44: Non-specific - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 30 "Mid piece, Principal piece" "CAB034046: , HPA001333: " "unprognostic (3.26e-2)" "unprognostic (3.06e-2)" "unprognostic (5.74e-1)" "unprognostic (1.33e-1)" "unprognostic (4.35e-2)" "unprognostic (1.86e-1)" "unprognostic (1.68e-3)" "unprognostic (2.11e-1)" "unprognostic (3.26e-1)" "potential prognostic unfavorable (2.45e-5)" "unprognostic (1.90e-3)" "unprognostic (1.43e-2)" "unprognostic (3.91e-2)" "unprognostic (8.93e-2)" "unprognostic (7.69e-2)" "unprognostic (1.47e-1)" "unprognostic (1.04e-2)" "unprognostic (8.97e-3)" "unprognostic (1.24e-1)" "unprognostic (1.06e-1)" "unprognostic (2.62e-1)" "unprognostic (1.08e-2)" "unprognostic (3.34e-1)" "unprognostic (3.15e-1)" "unprognostic (2.51e-1)" "potential prognostic unfavorable (8.35e-4)" "unprognostic (4.90e-2)" "unprognostic (2.06e-2)" "unprognostic (9.58e-2)" "unprognostic (1.19e-2)" "unprognostic (3.00e-3)" RAB27B ENSG00000041353 "RAB27B, member RAS oncogene family" O00194 18 54717860-54895516 "Enzymes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 41.7" "Cell type enhanced" "Detected in many" "Early spermatids: 274.6;Esophageal apical cells: 306.4;Foveolar cells: 566.9;Late spermatids: 295.3;Mast cells: 618.3;Megakaryocyte progenitors: 377.4;Megakaryocytes: 933.4;Platelets: 1213.7;Prostatic glandular cells: 289.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.2;NK-cell: 2.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Mast cells, Adrenal gland - Adrenal medulla cells, Lung - Alveolar cells type 2, Pituitary gland - Thyrotropes, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017712, HPA019849" Enhanced Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA 8900000 "Cluster 24: Non-specific - Transcription" "Cluster 60: Stomach - Digestion" "Cluster 14: Neurons - Synaptic function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 58: Mast cells - Allergic inflammatory responses" 23 "Golgi apparatus, Plasma membrane" Cytosol "CAB017712: , HPA019849: " "unprognostic (1.39e-1)" "unprognostic (1.34e-1)" "potential prognostic unfavorable (6.26e-4)" "unprognostic (3.48e-2)" "unprognostic (1.45e-2)" "unprognostic (5.48e-3)" "unprognostic (5.42e-2)" "unprognostic (1.88e-3)" "unprognostic (3.18e-2)" "unprognostic (4.48e-2)" "unprognostic (2.14e-3)" "unprognostic (6.30e-2)" "unprognostic (1.90e-3)" "unprognostic (1.19e-1)" "potential prognostic unfavorable (3.59e-4)" "unprognostic (8.39e-3)" "unprognostic (3.76e-2)" "unprognostic (3.57e-2)" "potential prognostic unfavorable (1.49e-4)" "unprognostic (2.16e-1)" "unprognostic (3.28e-2)" "unprognostic (1.07e-1)" "potential prognostic unfavorable (6.61e-4)" "unprognostic (1.90e-1)" "unprognostic (5.52e-1)" "unprognostic (6.18e-2)" RAB28 ENSG00000157869 "RAB28, member RAS oncogene family" P51157 4 13361354-13484365 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hydrolase "Cone-rod dystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Somatotrophs: 333.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044575 Approved NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 31: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 8 "HPA044575: " "unprognostic (1.61e-1)" "unprognostic (9.68e-2)" "unprognostic (2.33e-2)" "unprognostic (4.77e-2)" "unprognostic (1.49e-2)" "unprognostic (1.45e-1)" "unprognostic (9.14e-2)" "unprognostic (1.70e-1)" "unprognostic (2.12e-2)" "unprognostic (1.99e-2)" "unprognostic (2.64e-3)" "potential prognostic favorable (2.87e-4)" "unprognostic (1.91e-1)" "unprognostic (3.02e-2)" "unprognostic (4.39e-3)" "unprognostic (1.13e-2)" "unprognostic (3.44e-2)" "unprognostic (1.35e-1)" "unprognostic (3.26e-1)" "unprognostic (1.25e-1)" "unprognostic (2.85e-1)" "unprognostic (3.50e-3)" "unprognostic (4.54e-2)" "unprognostic (9.98e-2)" "unprognostic (1.10e-1)" "unprognostic (3.99e-2)" "unprognostic (3.31e-2)" "unprognostic (1.40e-1)" "unprognostic (1.93e-1)" "unprognostic (8.11e-3)" "unprognostic (1.84e-1)" RAB29 "RAB7L, RAB7L1" ENSG00000117280 "RAB29, member RAS oncogene family" O14966 1 205767986-205775482 "Predicted intracellular proteins" "Differentiation, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 68.2" "Cell type enhanced" "Detected in many" "NK-cells: 76.6" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 54.4;leukocyte: 52.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020822, HPA026303" Approved Approved "Nucleoplasm,Nuclear membrane,Vesicles,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 72: Kidney - Transmembrane transport" "Cluster 39: Astrocytes - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 47 "Nuclear membrane, Vesicles" "Nucleoplasm, Cytosol" "CAB020822: , HPA026303: " "unprognostic (1.33e-2)" "unprognostic (1.35e-1)" "unprognostic (5.87e-3)" "unprognostic (8.77e-2)" "unprognostic (3.26e-2)" "unprognostic (1.82e-1)" "unprognostic (1.24e-1)" "unprognostic (2.19e-1)" "unprognostic (1.22e-1)" "potential prognostic favorable (5.87e-6)" "unprognostic (1.68e-1)" "unprognostic (1.37e-1)" "potential prognostic unfavorable (2.55e-4)" "unprognostic (3.27e-2)" "unprognostic (5.19e-2)" "unprognostic (1.93e-1)" "unprognostic (4.31e-1)" "unprognostic (4.91e-2)" "unprognostic (1.56e-3)" "unprognostic (3.16e-1)" "unprognostic (3.32e-1)" "unprognostic (6.96e-2)" "unprognostic (1.90e-1)" "unprognostic (2.94e-3)" "unprognostic (1.30e-1)" "unprognostic (9.08e-2)" "unprognostic (1.49e-1)" "potential prognostic unfavorable (1.76e-4)" "unprognostic (2.99e-2)" RAB2A RAB2 ENSG00000104388 "RAB2A, member RAS oncogene family" P61019 8 60516936-60623644 "Enzymes, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 2185.7;Neutrophils: 1168.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB018781 Approved NA NA 400000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 40: Non-specific - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 131 "CAB018781: " "unprognostic (1.19e-3)" "unprognostic (3.07e-3)" "unprognostic (1.01e-1)" "potential prognostic unfavorable (6.11e-4)" "unprognostic (2.07e-1)" "unprognostic (1.47e-2)" "unprognostic (7.79e-2)" "unprognostic (1.68e-1)" "unprognostic (5.25e-2)" "unprognostic (3.62e-2)" "potential prognostic favorable (2.77e-4)" "unprognostic (1.30e-1)" "unprognostic (5.29e-2)" "unprognostic (3.03e-1)" "unprognostic (1.53e-1)" "potential prognostic unfavorable (2.61e-4)" "unprognostic (1.93e-1)" "unprognostic (3.56e-3)" "unprognostic (6.71e-2)" "unprognostic (5.66e-2)" "unprognostic (9.13e-3)" "unprognostic (1.51e-2)" "unprognostic (1.20e-1)" "unprognostic (2.72e-1)" "unprognostic (1.15e-1)" "unprognostic (1.88e-3)" "unprognostic (6.67e-2)" "unprognostic (1.29e-1)" "unprognostic (1.93e-1)" "unprognostic (7.42e-2)" "unprognostic (8.94e-2)" RAB2B FLJ14824 ENSG00000129472 "RAB2B, member RAS oncogene family" Q8WUD1 14 21459020-21476960 "Enzymes, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050292 Uncertain NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 65: Brain - Transcription" "Cluster 45: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 31 "HPA050292: " "unprognostic (1.91e-2)" "unprognostic (6.19e-3)" "unprognostic (1.92e-2)" "unprognostic (1.59e-1)" "unprognostic (1.55e-1)" "unprognostic (2.32e-1)" "unprognostic (2.92e-2)" "potential prognostic favorable (3.35e-4)" "unprognostic (1.30e-1)" "unprognostic (1.91e-2)" "unprognostic (9.47e-2)" "unprognostic (1.36e-2)" "unprognostic (3.70e-2)" "unprognostic (5.82e-2)" "unprognostic (9.67e-2)" "unprognostic (5.73e-2)" "unprognostic (2.32e-1)" "unprognostic (1.91e-1)" "unprognostic (2.62e-2)" "unprognostic (1.51e-1)" "unprognostic (7.52e-2)" "unprognostic (1.10e-1)" "unprognostic (7.27e-2)" "unprognostic (1.88e-1)" "unprognostic (5.18e-2)" "unprognostic (1.55e-1)" "unprognostic (5.02e-2)" "unprognostic (5.28e-2)" "unprognostic (8.06e-3)" "unprognostic (1.05e-1)" "unprognostic (3.01e-1)" RAB30 ENSG00000137502 "RAB30, member RAS oncogene family" Q15771 11 82973133-83071923 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 166.2;Fibro-adipogenic progenitors: 76.8;Myonuclei: 91.4;Oligodendrocytes: 128.2;Plasma cells: 211.3" "Cell type enhanced" "Detected in all" "oligodendrocyte: 200.9" "Cancer enhanced" "Detected in all" "Breast Invasive Carcinoma (TCGA): 25.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "memory B-cell: 54.7;naive B-cell: 55.3" "Lineage enriched" "Detected in many" 5 "B-cells: 55.3" "Cancer enhanced" "Detected in all" "lymphoma: 45.4" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054514, HPA060565" Approved Enhanced Vesicles NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 2 Vesicles "HPA054514: , HPA060565: " "unprognostic (1.63e-1)" "unprognostic (1.96e-1)" "unprognostic (1.54e-1)" "unprognostic (1.97e-1)" "unprognostic (6.83e-2)" "unprognostic (4.05e-2)" "unprognostic (1.01e-1)" "unprognostic (1.04e-1)" "unprognostic (4.54e-2)" "potential prognostic unfavorable (7.45e-4)" "unprognostic (3.14e-3)" "unprognostic (5.46e-2)" "unprognostic (5.09e-2)" "unprognostic (5.92e-2)" "unprognostic (1.25e-2)" "unprognostic (1.90e-3)" "unprognostic (5.29e-2)" "unprognostic (5.57e-2)" "unprognostic (1.19e-1)" "unprognostic (9.74e-3)" "unprognostic (1.50e-2)" "unprognostic (4.77e-2)" "unprognostic (3.08e-1)" "unprognostic (2.37e-1)" "unprognostic (2.05e-1)" "unprognostic (5.12e-2)" "unprognostic (1.46e-1)" "unprognostic (2.34e-1)" "unprognostic (8.96e-2)" "unprognostic (3.19e-1)" "unprognostic (3.22e-1)" RAB31 Rab22B ENSG00000168461 "RAB31, member RAS oncogene family" Q13636 18 9708275-9862551 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "cDC: 588.0;Kupffer cells: 772.8;Macrophages: 758.4;monocytes: 1014.6;Neutrophil progenitors: 1343.1;Neutrophils: 2273.6;Platelets: 594.3" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 430.5;oligodendrocyte precursor cell: 458.0" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 175.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 138.4" "Group enriched" "Detected in many" 8 "dendritic cells: 44.9;granulocytes: 138.4;monocytes: 51.6" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019717, HPA074046" Approved Supported "Golgi apparatus,Vesicles" NA NA "Cluster 32: Basophils - Transcription" "Cluster 73: Brain - Neuronal signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 15 "Golgi apparatus, Vesicles" "HPA019717: , HPA074046: " "unprognostic (4.78e-1)" "unprognostic (1.91e-1)" "unprognostic (5.02e-2)" "unprognostic (6.86e-3)" "unprognostic (8.10e-2)" "unprognostic (1.15e-1)" "unprognostic (4.80e-2)" "unprognostic (1.25e-1)" "unprognostic (3.65e-2)" "unprognostic (1.65e-1)" "unprognostic (1.96e-2)" "unprognostic (1.77e-2)" "unprognostic (1.10e-1)" "unprognostic (5.39e-3)" "unprognostic (9.44e-2)" "unprognostic (1.69e-1)" "unprognostic (3.45e-2)" "unprognostic (1.35e-1)" "unprognostic (6.50e-2)" "unprognostic (4.28e-3)" "unprognostic (1.95e-2)" "unprognostic (3.07e-2)" "unprognostic (7.65e-2)" "unprognostic (2.76e-1)" "unprognostic (1.57e-1)" "unprognostic (5.32e-3)" "unprognostic (5.80e-2)" "potential prognostic unfavorable (1.75e-5)" "unprognostic (3.18e-3)" "unprognostic (1.03e-1)" "unprognostic (1.30e-1)" RAB32 ENSG00000118508 "RAB32, member RAS oncogene family" Q13637 6 146543833-146554953 "Plasma proteins, Predicted intracellular proteins" Hydrolase "Disease variant, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 165.1" "Cell type enhanced" "Detected in many" "Hofbauer cells: 404.9;Kupffer cells: 558.6;Late spermatids: 241.8;Megakaryocytes: 463.6;Melanocytes: 306.6;Neutrophils: 228.3;Platelets: 1558.4" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 77.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 86.6" "Group enriched" "Detected in many" 42 "dendritic cells: 42.5;granulocytes: 86.6;monocytes: 46.9" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" HPA025731 Approved Approved Cytosol NA NA 110000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 15: Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 47: Platelets - Hemostasis" 13 Cytosol "HPA025731: " "unprognostic (2.29e-1)" "unprognostic (2.96e-1)" "unprognostic (5.83e-2)" "unprognostic (1.62e-1)" "unprognostic (4.37e-2)" "potential prognostic favorable (6.07e-5)" "unprognostic (1.28e-1)" "potential prognostic unfavorable (3.80e-4)" "unprognostic (4.80e-2)" "potential prognostic unfavorable (9.24e-4)" "potential prognostic favorable (8.81e-4)" "unprognostic (1.46e-1)" "unprognostic (1.10e-1)" "potential prognostic unfavorable (4.81e-10)" "unprognostic (4.50e-2)" "unprognostic (1.61e-1)" "unprognostic (2.16e-2)" "unprognostic (2.69e-1)" "unprognostic (1.89e-1)" "unprognostic (1.48e-2)" "unprognostic (2.89e-2)" "unprognostic (9.25e-2)" "unprognostic (1.71e-2)" "unprognostic (1.03e-1)" "unprognostic (2.06e-2)" "unprognostic (2.02e-1)" "unprognostic (2.17e-1)" "unprognostic (1.21e-2)" "unprognostic (1.77e-2)" "unprognostic (1.25e-1)" "unprognostic (2.06e-2)" RAB33A RabS10 ENSG00000134594 "RAB33A, member RAS oncogene family" Q14088 X 130171962-130184870 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 44.4;heart muscle: 19.8" "Cell type enhanced" "Detected in many" "Hematopoietic stem cells: 11.6;Hepatic stellate cells: 12.9;Mast cells: 15.5;Megakaryocyte progenitors: 11.7;Megakaryocytes: 86.5;Oligodendrocytes: 33.9;Platelets: 21.2;Retinal ganglion cells: 15.5;T-cells: 11.7" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 42.7;oligodendrocyte: 35.9" "Cancer enriched" "Detected in many" 4 "Glioblastoma Multiforme (TCGA): 25.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Leukemia: 25.4;lymphoma: 39.0;Myeloma: 34.3;Neuroblastoma: 18.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059737 Uncertain Uncertain Vesicles NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 9: T-cells - Adaptive immunity: Regulation" 27 Vesicles "HPA059737: " "unprognostic (2.45e-1)" "unprognostic (4.70e-2)" "unprognostic (1.00e-1)" "potential prognostic favorable (2.33e-4)" "unprognostic (1.32e-1)" "unprognostic (1.35e-1)" "potential prognostic favorable (1.46e-4)" "unprognostic (3.13e-3)" "unprognostic (1.75e-3)" "unprognostic (2.37e-2)" "unprognostic (3.07e-2)" "unprognostic (1.05e-1)" "unprognostic (5.76e-2)" "unprognostic (1.58e-1)" "unprognostic (2.02e-1)" "unprognostic (6.30e-2)" "unprognostic (3.16e-1)" "unprognostic (2.27e-2)" "unprognostic (6.39e-2)" "unprognostic (7.25e-2)" "unprognostic (1.30e-1)" RAB33B DKFZP434G099 ENSG00000172007 "RAB33B, member RAS oncogene family" Q9H082 4 139453232-139476609 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Autophagy, Protein transport, Transport" Hydrolase "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 89.4;Epicardial cells: 68.2;Late spermatids: 94.1;Neutrophil progenitors: 64.6;Neutrophils: 107.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 22.6" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048367 Uncertain NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 25: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 19 "HPA048367: " "unprognostic (1.51e-2)" "unprognostic (1.17e-1)" "unprognostic (1.33e-1)" "unprognostic (2.63e-2)" "unprognostic (2.59e-1)" "unprognostic (3.14e-2)" "unprognostic (1.67e-1)" "potential prognostic unfavorable (3.55e-4)" "unprognostic (2.45e-1)" "unprognostic (3.07e-1)" "potential prognostic favorable (2.20e-6)" "unprognostic (2.84e-3)" "unprognostic (2.28e-1)" "unprognostic (1.65e-1)" "unprognostic (1.71e-2)" "unprognostic (1.27e-1)" "unprognostic (2.56e-1)" "unprognostic (2.28e-1)" "unprognostic (2.56e-2)" "unprognostic (3.56e-1)" "unprognostic (7.06e-2)" "unprognostic (3.32e-2)" "unprognostic (1.09e-1)" "unprognostic (1.31e-2)" "unprognostic (7.98e-2)" "unprognostic (2.18e-1)" "unprognostic (6.74e-2)" "unprognostic (2.75e-2)" "unprognostic (4.83e-1)" "unprognostic (5.65e-3)" "unprognostic (7.08e-2)" RAB34 "NARR, RAB39, RAH" ENSG00000109113 "RAB34, member RAS oncogene family" "P0DI83, Q9BZG1" 17 28714281-28718429 "Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Transport" Hydrolase "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 128.3;Decidual stromal cells: 220.9;Epididymal basal cells: 127.2;Extravillous trophoblasts: 121.2;Hepatic stellate cells: 142.0;Ovarian stromal cells: 126.9;Peritubular myoid cells: 146.0;Smooth muscle cells: 125.3" "Cell type enhanced" "Detected in many" "astrocyte: 54.7;Bergmann glia: 104.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 51.1;intermediate monocyte: 47.3;myeloid DC: 76.4;non-classical monocyte: 23.5;plasmacytoid DC: 46.7" "Group enriched" "Detected in all" 5 "dendritic cells: 76.4;monocytes: 51.1" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021366 Approved Approved "Nucleoplasm,Primary cilium,Centrosome,Basal body,Cytosol" NA NA 1700000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 108: Fibroblasts - ECM organization" 2 "Nucleoplasm, Primary cilium" "Centrosome, Basal body, Cytosol" "HPA021366: " "unprognostic (1.14e-1)" "unprognostic (1.43e-1)" "unprognostic (1.46e-2)" "unprognostic (2.93e-1)" "unprognostic (3.60e-2)" "unprognostic (2.79e-1)" "unprognostic (2.32e-2)" "potential prognostic unfavorable (2.65e-6)" "unprognostic (3.81e-2)" "unprognostic (7.12e-3)" "unprognostic (5.25e-2)" "unprognostic (2.30e-2)" "unprognostic (5.49e-2)" "unprognostic (5.65e-2)" "unprognostic (1.73e-1)" "unprognostic (7.58e-2)" "unprognostic (2.67e-2)" "unprognostic (6.67e-2)" "unprognostic (1.01e-1)" "unprognostic (9.02e-3)" "unprognostic (2.11e-1)" "unprognostic (8.51e-2)" "unprognostic (5.25e-2)" "unprognostic (2.37e-2)" "unprognostic (9.35e-2)" "unprognostic (1.63e-2)" "unprognostic (1.18e-1)" "potential prognostic unfavorable (1.57e-4)" "unprognostic (4.02e-2)" "unprognostic (6.64e-3)" "unprognostic (6.20e-2)" RAB35 H-ray ENSG00000111737 "RAB35, member RAS oncogene family" Q15286 12 120095099-120117502 "Predicted intracellular proteins" "Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 95.1;Neutrophils: 109.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054146 Approved NA NA 4400000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 42 "HPA054146: " "unprognostic (5.13e-1)" "unprognostic (1.27e-2)" "unprognostic (6.24e-2)" "unprognostic (5.78e-2)" "unprognostic (3.41e-1)" "unprognostic (8.23e-3)" "unprognostic (3.57e-1)" "unprognostic (1.09e-1)" "unprognostic (3.38e-1)" "unprognostic (1.48e-1)" "unprognostic (2.00e-3)" "unprognostic (5.38e-2)" "unprognostic (1.97e-1)" "potential prognostic unfavorable (6.70e-5)" "unprognostic (2.29e-3)" "unprognostic (9.51e-3)" "unprognostic (1.33e-2)" "unprognostic (5.40e-3)" "unprognostic (3.71e-1)" "unprognostic (7.08e-2)" "unprognostic (2.58e-2)" "unprognostic (1.85e-1)" "unprognostic (3.99e-3)" "unprognostic (2.89e-1)" "unprognostic (2.46e-1)" "unprognostic (1.96e-2)" "unprognostic (3.77e-2)" "unprognostic (1.55e-1)" "unprognostic (2.70e-1)" "unprognostic (3.85e-1)" "unprognostic (9.65e-2)" RAB36 ENSG00000100228 "RAB36, member RAS oncogene family" O95755 22 23145366-23165663 "Predicted intracellular proteins" "Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 25.7" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 61.0;Ependymal cells: 33.4;Epididymal efferent duct ciliated cells: 46.2;Fallopian tube ciliated cells: 80.2;Late spermatids: 38.6;Respiratory ciliated cells: 141.6;Respiratory deuterosomal cells: 49.8" "Group enriched" "Detected in many" 4 "choroid plexus epithelial cell: 18.5;ependymal cell: 41.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 8 "neutrophil: 11.3" "Lineage enriched" "Detected in many" 8 "granulocytes: 11.3" "Cancer enhanced" "Detected in many" "Myeloma: 20.9" "Adipose visceral - Mesothelial cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059631 Uncertain Vesicles NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 107: Ciliated cells - Cilia assembly & function" 1 Vesicles "HPA059631: " "unprognostic (1.17e-1)" "unprognostic (1.02e-2)" "unprognostic (3.44e-1)" "unprognostic (1.40e-2)" "unprognostic (3.28e-1)" "unprognostic (4.11e-2)" "unprognostic (1.57e-2)" "potential prognostic unfavorable (4.59e-5)" "unprognostic (1.13e-1)" "unprognostic (2.40e-1)" "potential prognostic favorable (3.78e-4)" "unprognostic (8.39e-2)" "potential prognostic favorable (6.62e-4)" "unprognostic (4.63e-2)" "unprognostic (1.79e-1)" "unprognostic (2.76e-2)" "potential prognostic favorable (3.05e-4)" "unprognostic (1.02e-1)" "unprognostic (2.00e-2)" "unprognostic (1.45e-2)" "unprognostic (2.25e-1)" "unprognostic (1.50e-2)" "unprognostic (3.63e-2)" "unprognostic (1.92e-3)" "unprognostic (4.75e-2)" "unprognostic (2.35e-1)" "unprognostic (4.59e-2)" "unprognostic (6.97e-3)" "unprognostic (3.15e-2)" RAB37 ENSG00000172794 "RAB37, member RAS oncogene family" Q96AX2 17 74670578-74747335 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 23.1;brain: 36.8;lymphoid tissue: 19.8" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 88.1;Hematopoietic stem cells: 92.2;Mast cells: 79.1;Megakaryocyte progenitors: 54.8;Megakaryocyte-Erythroid progenitors: 65.5;Megakaryocytes: 136.0;Platelets: 435.0;Retinal amacrine cells: 154.6;Retinal ganglion cells: 146.8;Thymocytes: 77.9;Tuft cells: 103.8" "Cell type enhanced" "Detected in all" "upper rhombic lip: 234.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 269.5" "Lineage enriched" "Detected in all" 5 "granulocytes: 269.5" "Cancer enhanced" "Detected in many" "Leukemia: 42.8;Myeloma: 22.4" "Breast - T-cells, Prostate - Fibroblasts, Testis - Early spermatids, Thyroid gland - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 61: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 3 "unprognostic (2.30e-1)" "unprognostic (7.30e-2)" "unprognostic (8.68e-3)" "unprognostic (6.64e-2)" "unprognostic (7.08e-2)" "unprognostic (3.07e-3)" "unprognostic (1.30e-1)" "unprognostic (5.03e-2)" "unprognostic (2.76e-1)" "unprognostic (3.07e-1)" "unprognostic (1.78e-1)" "unprognostic (4.83e-3)" "unprognostic (6.65e-3)" "unprognostic (6.89e-2)" "unprognostic (1.07e-1)" "unprognostic (3.00e-1)" "unprognostic (2.39e-1)" "unprognostic (1.22e-1)" "unprognostic (3.42e-1)" "unprognostic (4.30e-2)" "unprognostic (1.07e-1)" RAB38 NY-MEL-1 ENSG00000123892 "RAB38, member RAS oncogene family" P57729 11 88113251-88175443 "Predicted intracellular proteins" "Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 47.9;skin 1: 43.2" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 49.3;Epididymal basal cells: 35.7;Mast cells: 60.6;Medullary thymic epithelial cells: 55.2;Melanocytes: 141.2;Ocular epithelial cells: 44.5;Retinal pigment epithelial cells: 59.7;Urothelial cells: 90.2" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 15.5;choroid plexus epithelial cell: 42.5;deep-layer near-projecting: 19.7" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 121.4" "Region enriched" "Detected in some" 11 "choroid plexus: 12.8" "Immune cell enriched" "Detected in many" 4 "NK-cell: 18.0" "Lineage enriched" "Detected in many" 4 "NK-cells: 18.0" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 88.3;skin cancer: 120.0" "Prostate - Urothelial cells, Skin - Keratinocyte (other), Testis - Spermatogonia" "Low region specificity" "Detected in many" "Region enhanced" "Detected in single" "basal ganglia: 1.3" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 69: Urothelial cells - Basic cellular functions" 24 "unprognostic (9.18e-2)" "unprognostic (7.72e-2)" "unprognostic (2.87e-1)" "unprognostic (5.31e-2)" "unprognostic (1.12e-1)" "unprognostic (1.58e-2)" "unprognostic (1.35e-2)" "unprognostic (7.26e-2)" "unprognostic (3.37e-2)" "unprognostic (3.50e-2)" "potential prognostic favorable (1.76e-5)" "unprognostic (1.85e-2)" "unprognostic (1.29e-3)" "unprognostic (2.29e-2)" "unprognostic (7.36e-2)" "potential prognostic unfavorable (4.27e-4)" "unprognostic (2.41e-1)" "unprognostic (1.24e-3)" "unprognostic (4.67e-2)" "unprognostic (1.28e-1)" "potential prognostic unfavorable (9.89e-4)" "unprognostic (9.93e-3)" "unprognostic (1.99e-1)" "unprognostic (9.91e-2)" "unprognostic (1.67e-2)" "unprognostic (2.08e-2)" "unprognostic (5.79e-2)" "unprognostic (7.13e-2)" "unprognostic (2.99e-2)" "unprognostic (2.41e-1)" RAB39A RAB39 ENSG00000179331 "RAB39A, member RAS oncogene family" Q14964 11 107928448-107963482 "Predicted intracellular proteins" "Autophagy, Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.7;lymphoid tissue: 2.8" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 21.3;cDC: 24.2;Cone photoreceptor cells: 70.4;Hofbauer cells: 18.2;Kupffer cells: 40.0;Macrophages: 34.5;Microglia: 82.3;monocytes: 26.8;Pancreatic islet cells: 37.8;Retinal ganglion cells: 38.6;Rod photoreceptor cells: 23.6" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 100.0" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 2.5;Testicular Germ Cell Tumor (TCGA): 2.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 2.2" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Neuroblastoma: 14.4" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Heart muscle - Macrophages, Liver - Kupffer cells, Minor Salivary Gland - Macrophages, Spleen - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA042505 Uncertain NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 44: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 9 "HPA042505: " "unprognostic (2.86e-2)" "unprognostic (2.82e-1)" "unprognostic (3.00e-1)" "unprognostic (2.06e-2)" "unprognostic (1.83e-1)" "unprognostic (1.98e-1)" "unprognostic (4.49e-3)" "unprognostic (2.72e-1)" RAB39B "MRX72, WSN" ENSG00000155961 "RAB39B, member RAS oncogene family" Q96DA2 X 155258235-155264491 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Autophagy, Protein transport, Transport" Hydrolase "Autism spectrum disorder, Disease variant, Intellectual disability, Parkinson disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.2;retina: 9.2" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 10.6;Brain excitatory neurons: 10.5;Brain inhibitory neurons: 10.3;Corticotrophs: 12.6;Epididymal principal cells: 13.4;Oligodendrocytes: 9.9;Other brain neurons: 10.7;Pancreatic islet cells: 18.6;Plasma cells: 13.5;T-cells: 11.3;Thyrotrophs: 9.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 10.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "lymphoma: 10.3;Myeloma: 13.7" "Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001114, HPA042505" Approved NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 27: Cerebellum - Synaptic function" "Cluster 14: Neurons - Synaptic function" "Cluster 13: Non-specific - Mixed function" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 16 "HPA001114: , HPA042505: " "potential prognostic favorable (5.90e-4)" "unprognostic (4.90e-2)" "unprognostic (1.85e-1)" "unprognostic (2.23e-2)" "unprognostic (1.15e-2)" "unprognostic (1.43e-1)" "unprognostic (1.92e-1)" "unprognostic (3.92e-1)" "potential prognostic favorable (3.62e-4)" "unprognostic (1.32e-1)" "unprognostic (7.10e-2)" "unprognostic (2.80e-2)" "unprognostic (3.36e-2)" RAB3A ENSG00000105649 "RAB3A, member RAS oncogene family" P20336 19 18196784-18204042 "Predicted intracellular proteins" "Exocytosis, Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 340.1" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 50.9;Brain inhibitory neurons: 57.9;Cone photoreceptor cells: 33.1;Oocytes: 32.2;Other brain neurons: 60.1;Ovarian stromal cells: 48.3;Retinal amacrine cells: 59.0;Retinal bipolar cells: 57.4;Retinal horizontal cells: 64.1;Rod photoreceptor cells: 34.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 30.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Neuroblastoma: 32.2" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003160, CAB009949, CAB078998" Enhanced Supported Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 98: Neurons - Neurotransmission & signaling" 35 Nucleoplasm "Centrosome, Cytosol" "CAB009949: , CAB078998: , HPA003160: " "unprognostic (3.66e-3)" "unprognostic (1.12e-1)" "unprognostic (4.45e-1)" "unprognostic (1.16e-1)" "unprognostic (2.50e-2)" "potential prognostic unfavorable (9.45e-4)" "unprognostic (4.78e-2)" "unprognostic (1.16e-1)" "unprognostic (2.35e-1)" "unprognostic (8.40e-2)" "unprognostic (1.12e-3)" "unprognostic (6.54e-2)" "potential prognostic favorable (3.55e-4)" "unprognostic (3.36e-2)" "unprognostic (1.16e-1)" "unprognostic (2.90e-2)" "unprognostic (2.20e-1)" "unprognostic (6.76e-3)" "unprognostic (6.42e-2)" "unprognostic (1.47e-1)" "unprognostic (5.03e-2)" "unprognostic (2.25e-2)" "unprognostic (7.21e-2)" "unprognostic (1.48e-1)" "unprognostic (9.71e-3)" "unprognostic (5.73e-2)" "unprognostic (9.97e-2)" "unprognostic (7.74e-2)" "unprognostic (4.45e-2)" "unprognostic (9.40e-3)" "unprognostic (1.59e-1)" RAB3B ENSG00000169213 "RAB3B, member RAS oncogene family" P20337 1 51907956-51990700 "Predicted intracellular proteins" "Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.5;pituitary gland: 10.0;prostate: 10.3" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 85.1;Corticotrophs: 1074.8;Neuroendocrine cells: 199.5;Other brain neurons: 71.1;Pancreatic islet cells: 269.9;Prostatic glandular cells: 182.1" "Cell type enhanced" "Detected in many" "MGE interneuron: 148.3" "Group enriched" "Detected in many" 6 "Prostate Adenocarcinoma (TCGA): 27.8;Testicular Germ Cell Tumor (TCGA): 11.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enteroendocrine cells, Kidney - Intercalated cells, Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Pancreas - Beta cells, Pituitary gland - Corticotropes, Prostate - Prostate glandular cells, Spleen - Plasma cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003159, CAB023293" Enhanced Approved "Cell Junctions" NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 1: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 21 "Cell Junctions" "CAB023293: , HPA003159: " "unprognostic (5.79e-2)" "unprognostic (2.82e-1)" "unprognostic (8.34e-2)" "unprognostic (7.06e-2)" "unprognostic (2.24e-2)" "unprognostic (3.58e-2)" "unprognostic (1.12e-3)" "unprognostic (1.88e-1)" "unprognostic (3.66e-3)" "unprognostic (1.72e-2)" "unprognostic (2.54e-3)" "unprognostic (6.56e-3)" "unprognostic (8.69e-2)" "potential prognostic favorable (4.57e-4)" "unprognostic (3.41e-2)" "unprognostic (5.46e-2)" "unprognostic (1.22e-1)" "unprognostic (4.47e-1)" "unprognostic (1.67e-1)" "unprognostic (2.67e-3)" "unprognostic (8.61e-2)" "unprognostic (9.87e-2)" RAB3C ENSG00000152932 "RAB3C, member RAS oncogene family" Q96E17 5 58582221-58859394 "Predicted intracellular proteins" "Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 8.5;brain: 31.9" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 255.3;Brain excitatory neurons: 190.5;Brain inhibitory neurons: 416.6;Corticotrophs: 615.1;Lactotrophs: 300.7;Megakaryocytes: 241.1;Neuroendocrine cells: 374.1;Oligodendrocyte progenitor cells: 170.0;Other brain neurons: 601.3;Pancreatic islet cells: 160.7;Retinal amacrine cells: 212.4;Retinal bipolar cells: 162.4;Somatotrophs: 140.9" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 1.7;Pancreatic Adenocarcinoma (TCGA): 1.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Neuroblastoma: 6.4" "Adipose visceral - Endothelial cells, Adrenal gland - Adrenal medulla cells, Breast - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003160, HPA048156" Enhanced Approved Cytosol NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 9 Cytosol "HPA003160: , HPA048156: " "unprognostic (1.14e-1)" "unprognostic (1.15e-1)" "unprognostic (3.20e-3)" "unprognostic (1.23e-1)" "potential prognostic favorable (6.89e-4)" "unprognostic (1.97e-1)" RAB3D "D2-2, GOV, RAB16, RAD3D" ENSG00000105514 "RAB3D, member RAS oncogene family" O95716 19 11322068-11346270 "Plasma proteins, Predicted intracellular proteins" "Exocytosis, Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 64.5;skin 1: 50.1" "Cell type enhanced" "Detected in many" "Neutrophil progenitors: 47.9;Neutrophils: 76.7;Pancreatic acinar cells: 26.6;Papillary tip epithelial cells: 24.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 169.2" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Spleen - Neutrophils_2, Stomach - Chief cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "spinal cord: 95.9" "CAB018067, HPA063283" Approved Approved Vesicles NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 60: Stomach - Digestion" "Cluster 43: Hindbrain - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 9 Vesicles "CAB018067: , HPA063283: " "unprognostic (2.14e-2)" "unprognostic (1.11e-2)" "unprognostic (3.74e-2)" "unprognostic (1.93e-1)" "unprognostic (9.65e-2)" "unprognostic (1.60e-1)" "unprognostic (3.56e-3)" "potential prognostic unfavorable (3.25e-5)" "potential prognostic favorable (7.93e-4)" "unprognostic (3.94e-1)" "unprognostic (5.07e-3)" "unprognostic (3.26e-1)" "unprognostic (1.41e-1)" "unprognostic (1.93e-3)" "unprognostic (4.77e-3)" "unprognostic (2.16e-1)" "unprognostic (2.18e-1)" "unprognostic (2.32e-1)" "unprognostic (1.47e-2)" "unprognostic (1.72e-1)" "unprognostic (1.82e-2)" "unprognostic (1.63e-1)" "unprognostic (1.60e-1)" "unprognostic (1.23e-1)" "unprognostic (8.83e-2)" "unprognostic (8.25e-3)" "unprognostic (1.48e-1)" "unprognostic (9.99e-2)" "unprognostic (5.92e-2)" "unprognostic (1.55e-1)" "unprognostic (5.48e-2)" RAB3GAP1 "KIAA0066, RAB3GAP, RAB3GAP130, WARBM1" ENSG00000115839 "RAB3 GTPase activating protein catalytic subunit 1" Q15042 2 135052289-135176667 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "GTPase activation" "Cataract, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034494, HPA034495" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 7: Non-specific - Transcription" 16 Nucleoplasm Cytosol "HPA034494: , HPA034495: " "unprognostic (4.13e-2)" "unprognostic (1.12e-3)" "unprognostic (3.55e-1)" "unprognostic (1.14e-2)" "unprognostic (2.00e-1)" "unprognostic (6.91e-2)" "unprognostic (2.31e-1)" "unprognostic (1.77e-1)" "unprognostic (8.28e-2)" "unprognostic (1.40e-2)" "potential prognostic favorable (9.87e-7)" "unprognostic (1.68e-3)" "unprognostic (8.60e-2)" "unprognostic (5.63e-2)" "unprognostic (4.54e-2)" "unprognostic (4.97e-3)" "unprognostic (6.81e-2)" "unprognostic (1.06e-1)" "unprognostic (1.40e-1)" "unprognostic (4.77e-2)" "unprognostic (3.69e-2)" "unprognostic (5.86e-3)" "unprognostic (8.79e-2)" "unprognostic (2.96e-1)" "unprognostic (3.39e-1)" "unprognostic (7.01e-2)" "unprognostic (9.54e-2)" "unprognostic (3.95e-2)" "unprognostic (1.79e-1)" "unprognostic (1.24e-1)" "unprognostic (4.51e-1)" RAB3GAP2 "DKFZP434D245, KIAA0839, RAB3-GAP150, SPG69" ENSG00000118873 "RAB3 GTPase activating non-catalytic protein subunit 2" Q9H2M9 1 220148293-220272529 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Cataract, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026273, HPA027299" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 32: Basophils - Transcription" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 44: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" 15 Cytosol "Plasma membrane" "HPA026273: , HPA027299: " "unprognostic (4.97e-2)" "potential prognostic unfavorable (3.13e-5)" "unprognostic (2.60e-1)" "unprognostic (1.13e-2)" "unprognostic (1.30e-1)" "unprognostic (1.32e-3)" "unprognostic (7.90e-2)" "unprognostic (9.49e-3)" "unprognostic (4.11e-2)" "unprognostic (1.77e-2)" "potential prognostic favorable (8.96e-6)" "unprognostic (8.17e-2)" "unprognostic (2.79e-2)" "unprognostic (3.65e-2)" "unprognostic (2.58e-1)" "unprognostic (4.36e-2)" "unprognostic (1.38e-1)" "unprognostic (1.42e-1)" "unprognostic (1.11e-1)" "unprognostic (9.52e-2)" "potential prognostic unfavorable (2.57e-5)" "unprognostic (1.89e-2)" "potential prognostic unfavorable (2.30e-4)" "unprognostic (4.33e-2)" "unprognostic (3.62e-2)" "unprognostic (4.55e-2)" "unprognostic (1.06e-2)" "unprognostic (8.62e-2)" "unprognostic (1.28e-1)" "unprognostic (7.01e-2)" "unprognostic (1.43e-1)" RAB3IL1 GRAB ENSG00000167994 "RAB3A interacting protein like 1" Q8TBN0 11 61897301-61920269 "Predicted intracellular proteins" "Protein transport, Transport" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 126.6;Hofbauer cells: 146.1;Kupffer cells: 51.2;Late spermatids: 191.2;Leydig cells: 57.2;Lymphatic endothelial cells: 28.4;Peritubular myoid cells: 46.1" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 19.2;fibroblast: 32.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Heart muscle - Fibroblasts, Lung - Fibroblasts_2, Prostate - Fibroblasts, Stomach - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039723 Uncertain Approved "Centriolar satellite,Cytosol" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 36 "Centriolar satellite, Cytosol" "HPA039723: " "unprognostic (1.08e-1)" "unprognostic (1.53e-1)" "unprognostic (1.17e-1)" "potential prognostic unfavorable (2.79e-4)" "potential prognostic unfavorable (4.46e-4)" "unprognostic (1.56e-1)" "unprognostic (2.67e-1)" "unprognostic (2.40e-1)" "unprognostic (3.43e-3)" "unprognostic (4.41e-2)" "unprognostic (6.65e-2)" "unprognostic (1.27e-1)" "unprognostic (1.30e-1)" "validated prognostic unfavorable (1.68e-6)" "validated prognostic unfavorable (1.73e-4)" "unprognostic (1.09e-1)" "unprognostic (1.63e-1)" "unprognostic (7.27e-2)" "unprognostic (9.57e-2)" "unprognostic (1.15e-1)" "unprognostic (2.59e-2)" "unprognostic (3.22e-1)" "unprognostic (2.46e-1)" "unprognostic (3.25e-2)" "unprognostic (1.34e-1)" "unprognostic (2.78e-2)" "unprognostic (6.24e-2)" "unprognostic (4.23e-2)" "unprognostic (1.64e-1)" "potential prognostic unfavorable (3.55e-5)" "unprognostic (1.51e-1)" RAB3IP "FLJ22548, RABIN3, RABIN8" ENSG00000127328 "RAB3A interacting protein" Q96QF0 12 69738860-69823204 "Predicted intracellular proteins" "Protein transport, Transport" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 109.6" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 315.6;Early spermatids: 219.1;Late spermatids: 475.1;Retinal pigment epithelial cells: 230.2" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 250.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039794, HPA057728" Uncertain Supported Nucleoplasm,Centrosome,Cytosol NA No "Cluster 24: Non-specific - Transcription" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 51: Secretory epithelial cells - Mixed function" 38 Nucleoplasm "Centrosome, Cytosol" "HPA039794: , HPA057728: " "unprognostic (2.77e-2)" "unprognostic (5.62e-2)" "unprognostic (2.61e-1)" "unprognostic (2.97e-1)" "unprognostic (1.86e-2)" "unprognostic (7.27e-3)" "unprognostic (4.25e-3)" "unprognostic (2.41e-2)" "unprognostic (2.31e-2)" "unprognostic (1.06e-2)" "potential prognostic favorable (1.43e-9)" "unprognostic (7.55e-3)" "potential prognostic favorable (8.78e-4)" "potential prognostic unfavorable (8.06e-4)" "unprognostic (2.84e-2)" "unprognostic (1.73e-2)" "unprognostic (4.45e-2)" "unprognostic (1.44e-1)" "unprognostic (1.01e-1)" "unprognostic (1.35e-1)" "unprognostic (8.81e-2)" "unprognostic (2.39e-1)" "unprognostic (1.69e-3)" "unprognostic (8.99e-2)" "unprognostic (8.11e-3)" "unprognostic (3.95e-1)" "unprognostic (1.76e-1)" "unprognostic (4.16e-1)" "unprognostic (3.90e-1)" "unprognostic (6.45e-2)" "unprognostic (1.15e-1)" RAB40A "Rar-2, RAR2A" ENSG00000172476 "RAB40A, member RAS oncogene family" Q8WXH6 X 103499130-103519489 "Cancer-related genes, Predicted intracellular proteins" "Ubl conjugation pathway" Hydrolase "Cancer-related genes" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "epididymis: 7.6" "Cell type enriched" "Detected in many" 4 "Epicardial cells: 211.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells" HPA076172 Uncertain Vesicles NA NA "Cluster 21: Testis - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 8 Vesicles "HPA076172: " "unprognostic (9.97e-2)" "unprognostic (2.33e-1)" "unprognostic (4.38e-2)" "unprognostic (2.43e-2)" "unprognostic (8.69e-2)" "unprognostic (1.26e-1)" "unprognostic (3.05e-1)" "unprognostic (9.91e-2)" "unprognostic (1.66e-2)" RAB40AL "RAR2, RLGP" ENSG00000102128 "RAB40A like" P0C0E4 X 102937272-102938300 "Predicted intracellular proteins" "Ubl conjugation pathway" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 4 "Sertoli cells: 2.8" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA076172 Uncertain Vesicles NA NA "Cluster 24: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 2 Vesicles "HPA076172: " "unprognostic (6.59e-3)" RAB40B "RAR, SEC4L" ENSG00000141542 "RAB40B, member RAS oncogene family" Q12829 17 82654973-82698698 "Predicted intracellular proteins" "Ubl conjugation pathway" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 106.4" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 141.9;Endometrial luminal cells: 124.0;Epididymal clear cells: 130.6;Oligodendrocytes: 184.8" "Cell type enhanced" "Detected in all" "oligodendrocyte: 241.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 6.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076172 Approved Vesicles NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 51: Secretory epithelial cells - Mixed function" 19 Vesicles "HPA076172: " "unprognostic (2.47e-1)" "unprognostic (2.26e-1)" "unprognostic (1.25e-1)" "unprognostic (2.89e-1)" "unprognostic (8.46e-2)" "unprognostic (2.94e-2)" "unprognostic (1.39e-1)" "unprognostic (6.23e-3)" "unprognostic (6.65e-2)" "unprognostic (3.79e-2)" "potential prognostic favorable (2.04e-7)" "unprognostic (1.09e-3)" "potential prognostic unfavorable (7.58e-4)" "unprognostic (1.02e-2)" "potential prognostic unfavorable (1.36e-4)" "unprognostic (1.49e-2)" "unprognostic (1.77e-1)" "unprognostic (7.80e-2)" "unprognostic (2.49e-2)" "unprognostic (6.14e-2)" "unprognostic (1.10e-1)" "unprognostic (1.13e-1)" "unprognostic (3.97e-2)" "unprognostic (2.44e-2)" "unprognostic (3.82e-2)" "unprognostic (4.75e-2)" "unprognostic (5.13e-2)" "unprognostic (2.61e-2)" "unprognostic (1.30e-1)" "unprognostic (2.20e-2)" "unprognostic (1.29e-1)" RAB40C "RARL, RASL8C" ENSG00000197562 "RAB40C, member RAS oncogene family" Q96S21 16 589357-629272 "Predicted intracellular proteins" "Ubl conjugation pathway" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 14.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 14.0" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Pituitary gland - Corticotropes, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076172 Approved Vesicles NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 2: Non-specific - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 28 Vesicles "HPA076172: " "unprognostic (2.00e-1)" "potential prognostic unfavorable (2.52e-4)" "unprognostic (7.89e-2)" "unprognostic (9.46e-2)" "unprognostic (5.14e-2)" "unprognostic (1.07e-1)" "unprognostic (3.10e-2)" "unprognostic (6.50e-3)" "unprognostic (7.64e-2)" "unprognostic (7.15e-2)" "potential prognostic favorable (2.62e-4)" "unprognostic (5.32e-2)" "unprognostic (1.43e-1)" "potential prognostic unfavorable (1.89e-4)" "unprognostic (2.03e-1)" "unprognostic (7.05e-2)" "unprognostic (1.89e-1)" "unprognostic (1.24e-1)" "unprognostic (2.79e-2)" "unprognostic (9.34e-2)" "unprognostic (3.35e-1)" "unprognostic (1.83e-1)" "unprognostic (1.92e-1)" "unprognostic (5.05e-1)" "unprognostic (1.59e-2)" "unprognostic (4.31e-1)" "unprognostic (1.12e-1)" "unprognostic (7.32e-2)" "unprognostic (2.07e-1)" "unprognostic (3.90e-2)" "unprognostic (4.39e-1)" RAB41 ENSG00000147127 "RAB41, member RAS oncogene family" Q5JT25 X 70282093-70285002 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "retina: 53.5" "Cell type enriched" "Detected in some" 7 "Cone photoreceptor cells: 229.8" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Glioblastoma Multiforme (TCGA): 4.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001510, HPA065289" Uncertain Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 42: Retina - Visual perception" "Cluster 19: Astrocytes - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 79: Photoreceptor cells - Phototransduction" 4 Cytosol "Vesicles, Plasma membrane" "HPA001510: , HPA065289: " "unprognostic (1.94e-1)" "unprognostic (2.38e-1)" "unprognostic (1.18e-1)" "unprognostic (7.15e-2)" "unprognostic (3.40e-1)" "unprognostic (4.45e-1)" RAB42 MGC45806 ENSG00000188060 "RAB42, member RAS oncogene family" Q8N4Z0 1 28592200-28595449 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 22.8" "Cell type enriched" "Detected in some" 11 "Hofbauer cells: 161.0" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 1.8;pericyte: 1.4" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 23.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 14.5;Kidney cancer: 17.5" "Lung - Macrophages, Skeletal muscle - Fibroblasts, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050290 Approved "Endoplasmic reticulum" NA NA "Cluster 80: Thymus - Adaptive immune response" "Cluster 6: Non-specific - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" "Endoplasmic reticulum" "HPA050290: " "unprognostic (1.08e-2)" "unprognostic (1.37e-1)" "unprognostic (1.25e-2)" "unprognostic (5.33e-3)" "unprognostic (2.98e-2)" "unprognostic (3.10e-1)" "unprognostic (4.84e-3)" "unprognostic (8.56e-3)" "unprognostic (5.44e-2)" "unprognostic (1.68e-1)" "unprognostic (3.56e-1)" "unprognostic (4.95e-1)" "unprognostic (4.55e-3)" "potential prognostic unfavorable (7.74e-5)" "unprognostic (8.29e-2)" "unprognostic (1.44e-1)" "unprognostic (1.65e-3)" "unprognostic (1.12e-1)" "unprognostic (3.33e-1)" "unprognostic (1.81e-3)" "unprognostic (1.44e-1)" "unprognostic (1.29e-2)" "unprognostic (2.09e-2)" "unprognostic (1.88e-2)" "unprognostic (2.60e-1)" "unprognostic (1.07e-1)" "unprognostic (3.74e-1)" "unprognostic (9.36e-2)" "unprognostic (1.09e-1)" "unprognostic (4.31e-2)" "unprognostic (4.02e-2)" RAB43 "ISY1, RAB11B, RAB41" ENSG00000172780 "RAB43, member RAS oncogene family" Q86YS6 3 129087569-129122801 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 44.2" "Cell type enhanced" "Detected in some" "Astrocytes: 4.4;Bergmann glia: 4.0;Brain excitatory neurons: 10.5;Brain inhibitory neurons: 10.4;Choroid plexus epithelial cells: 15.8;Ependymal cells: 4.7;Microglia: 19.7;Oligodendrocyte progenitor cells: 3.9;Oligodendrocytes: 3.9;Other brain neurons: 5.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 11.2" "Group enriched" "Detected in many" 5 "granulocytes: 11.2;T-cells: 2.8" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046840, HPA060085" Enhanced Supported "Plasma membrane" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 15: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 22: Non-specific - Basic cellular functions" 16 "Plasma membrane" "HPA046840: , HPA060085: " "unprognostic (7.33e-2)" "unprognostic (4.35e-1)" "unprognostic (2.34e-2)" "unprognostic (2.46e-2)" "unprognostic (1.15e-1)" "unprognostic (1.82e-1)" "unprognostic (6.99e-2)" "unprognostic (4.21e-1)" "unprognostic (2.52e-2)" "unprognostic (6.46e-2)" "unprognostic (2.91e-1)" "unprognostic (1.39e-1)" "unprognostic (2.18e-2)" "unprognostic (1.14e-1)" "unprognostic (4.95e-3)" "unprognostic (4.10e-3)" "unprognostic (1.76e-3)" "unprognostic (1.83e-1)" "unprognostic (9.30e-2)" "unprognostic (3.38e-1)" "unprognostic (5.99e-2)" "unprognostic (1.44e-1)" "unprognostic (3.95e-1)" "unprognostic (2.08e-1)" "unprognostic (1.26e-1)" "unprognostic (1.57e-2)" "unprognostic (6.30e-2)" "unprognostic (5.44e-2)" "unprognostic (1.65e-1)" "unprognostic (3.16e-2)" RAB44 "dJ431A14.3, RASD3, RASL13" ENSG00000255587 "RAB44, member RAS oncogene family" Q7Z6P3 6 36697826-36733184 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 41 "bone marrow: 55.6" "Cell type enhanced" "Detected in many" "Endometrial luminal cells: 23.0;Epicardial cells: 61.4;Mast cells: 78.1;Monocyte progenitors: 54.0;Neutrophil progenitors: 88.3;Salivary acinar cells: 16.6;Salivary myoepithelial cells: 33.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "basophil: 10.6;eosinophil: 7.2" "Lineage enriched" "Detected in single" 12 "granulocytes: 10.6" "Cancer enriched" "Detected in single" 135 "Leukemia: 26.6" "Adipose subcutaneous - Mast cells, Adipose visceral - Mast cells, Breast - Fibroblasts, Colon - Mast cells, Kidney - T-cells, Minor Salivary Gland - Mast cells, Prostate - Fibroblasts, Spleen - Neutrophils_1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA079390 Approved Vesicles NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 15: Bone marrow - Innate immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" Vesicles "HPA079390: " RAB4A "HRES-1/RAB4, RAB4" ENSG00000168118 "RAB4A, member RAS oncogene family" P20338 1 229271062-229305894 "Enzymes, Predicted intracellular proteins" "Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Gastric chief cells: 342.9;Parietal cells: 592.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 32.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 32.8" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 1900000 "Cluster 45: Eosinophils - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 38: Sub-cortical - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 97: Non-specific - Cellular respiration" 126 "unprognostic (1.13e-1)" "unprognostic (2.17e-2)" "unprognostic (2.35e-1)" "unprognostic (9.42e-2)" "unprognostic (1.79e-2)" "unprognostic (1.29e-1)" "unprognostic (9.61e-3)" "unprognostic (1.79e-1)" "unprognostic (1.48e-1)" "unprognostic (1.69e-1)" "potential prognostic favorable (1.49e-5)" "unprognostic (4.05e-2)" "unprognostic (1.94e-2)" "unprognostic (2.43e-1)" "unprognostic (2.65e-1)" "unprognostic (1.38e-1)" "unprognostic (2.26e-1)" "unprognostic (1.28e-1)" "unprognostic (1.89e-2)" "unprognostic (1.17e-1)" "unprognostic (3.66e-2)" "unprognostic (1.21e-1)" "unprognostic (1.43e-1)" "unprognostic (3.48e-1)" "unprognostic (2.03e-1)" "unprognostic (1.69e-2)" "unprognostic (3.23e-1)" "unprognostic (3.45e-2)" "unprognostic (1.04e-2)" "unprognostic (7.72e-2)" "unprognostic (1.28e-1)" RAB4B "FLJ78649, MGC52123" ENSG00000167578 "RAB4B, member RAS oncogene family" P61018 19 40778216-40796942 "Enzymes, Predicted intracellular proteins" "Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 108.8" "Group enriched" "Detected in some" 7 "Astrocytes: 32.7;Bergmann glia: 26.0;Brain excitatory neurons: 19.6;Brain inhibitory neurons: 16.8;Choroid plexus epithelial cells: 22.8;Ependymal cells: 23.5;Microglia: 37.0;Oligodendrocyte progenitor cells: 20.1;Oligodendrocytes: 57.6;Other brain neurons: 19.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 1800000 "Cluster 29: Non-specific - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 27: Non-specific - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 22: Non-specific - Basic cellular functions" 6 "unprognostic (1.52e-1)" "unprognostic (1.11e-1)" "unprognostic (1.84e-1)" "unprognostic (2.31e-2)" "unprognostic (1.62e-2)" "unprognostic (3.14e-1)" "unprognostic (3.01e-1)" "unprognostic (3.00e-1)" "unprognostic (4.55e-3)" "unprognostic (9.44e-2)" "unprognostic (6.88e-3)" "unprognostic (2.61e-1)" "unprognostic (3.40e-3)" "unprognostic (9.22e-2)" "unprognostic (8.68e-3)" "unprognostic (1.46e-1)" "unprognostic (3.18e-1)" "unprognostic (2.73e-1)" "unprognostic (5.53e-2)" "unprognostic (2.22e-1)" "unprognostic (5.84e-2)" "potential prognostic favorable (4.11e-5)" "unprognostic (6.93e-2)" "unprognostic (4.46e-2)" "unprognostic (2.15e-2)" "unprognostic (8.84e-2)" "unprognostic (2.37e-1)" "unprognostic (2.46e-1)" "unprognostic (1.88e-1)" "unprognostic (5.41e-2)" "unprognostic (3.15e-1)" RAB5A RAB5 ENSG00000144566 "RAB5A, member RAS oncogene family" P20339 3 19947097-19985175 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Endocytosis, Phagocytosis, Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 511.0;Neutrophils: 548.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004567, HPA049354" Approved Supported Nucleoplasm,Vesicles NA NA 170000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 27: Non-specific - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 113 "Nucleoplasm, Vesicles" "CAB004567: , HPA049354: " "unprognostic (1.64e-2)" "unprognostic (2.15e-3)" "unprognostic (2.56e-1)" "unprognostic (3.88e-2)" "unprognostic (4.19e-1)" "unprognostic (4.55e-2)" "unprognostic (2.94e-1)" "unprognostic (3.68e-2)" "unprognostic (1.05e-1)" "unprognostic (1.90e-3)" "unprognostic (1.76e-3)" "unprognostic (2.62e-2)" "unprognostic (4.74e-1)" "unprognostic (2.14e-2)" "unprognostic (1.76e-1)" "unprognostic (3.89e-2)" "unprognostic (3.20e-2)" "unprognostic (1.65e-2)" "unprognostic (1.91e-1)" "unprognostic (3.82e-2)" "unprognostic (7.12e-2)" "unprognostic (4.38e-3)" "unprognostic (2.51e-2)" "unprognostic (5.90e-2)" "unprognostic (4.74e-2)" "unprognostic (1.83e-1)" "unprognostic (2.53e-1)" "unprognostic (2.71e-2)" "unprognostic (1.91e-1)" "unprognostic (1.17e-1)" "unprognostic (8.88e-2)" RAB5B ENSG00000111540 "RAB5B, member RAS oncogene family" P61020 12 55973913-55996683 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 356.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Liver - Hepatocytes, Lung - Alveolar cells type 1, Prostate - Smooth muscle cells, Skin - Keratinocyte (other), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010224, HPA068337" Approved Supported Vesicles NA NA 210000 "Cluster 45: Eosinophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 28 Vesicles "CAB010224: , HPA068337: " "unprognostic (1.60e-1)" "unprognostic (2.49e-3)" "unprognostic (6.89e-2)" "unprognostic (1.07e-1)" "unprognostic (6.56e-2)" "unprognostic (2.35e-1)" "unprognostic (1.08e-1)" "unprognostic (2.71e-1)" "unprognostic (3.59e-2)" "unprognostic (3.51e-3)" "potential prognostic favorable (3.86e-6)" "unprognostic (1.43e-2)" "unprognostic (1.49e-1)" "unprognostic (1.24e-1)" "unprognostic (6.13e-3)" "unprognostic (2.65e-1)" "unprognostic (1.15e-1)" "unprognostic (9.63e-2)" "unprognostic (1.25e-1)" "unprognostic (2.04e-2)" "potential prognostic unfavorable (7.75e-4)" "unprognostic (5.51e-2)" "unprognostic (3.43e-1)" "unprognostic (1.23e-1)" "unprognostic (6.20e-2)" "unprognostic (2.78e-1)" "unprognostic (3.04e-1)" "unprognostic (3.80e-2)" "unprognostic (2.14e-1)" "unprognostic (1.13e-1)" "unprognostic (1.35e-1)" RAB5C "RAB5CL, RABL" ENSG00000108774 "RAB5C, member RAS oncogene family" P51148 17 42124978-42155044 "Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 33.9;Late primary spermatocytes: 22.7;Late spermatids: 67.1;Parietal cells: 14.1" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Colon - Macrophages, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003426, HPA004167" Approved Enhanced Endosomes NA NA 570000 "Cluster 7: Non-specific - Innate immune response" "Cluster 28: Liver & Adrenal gland - Secretion" "Cluster 19: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 84 Endosomes "HPA003426: , HPA004167: " "unprognostic (2.78e-2)" "unprognostic (2.24e-2)" "unprognostic (6.92e-2)" "potential prognostic unfavorable (8.83e-4)" "unprognostic (7.86e-2)" "unprognostic (1.03e-1)" "unprognostic (8.88e-2)" "unprognostic (1.35e-1)" "unprognostic (5.30e-2)" "unprognostic (2.82e-3)" "potential prognostic favorable (1.34e-7)" "unprognostic (1.05e-2)" "unprognostic (4.33e-2)" "unprognostic (1.83e-3)" "unprognostic (1.32e-2)" "unprognostic (3.09e-2)" "unprognostic (2.57e-2)" "unprognostic (1.98e-2)" "unprognostic (2.73e-1)" "unprognostic (2.48e-2)" "unprognostic (2.94e-2)" "unprognostic (6.69e-2)" "unprognostic (2.16e-1)" "unprognostic (2.42e-1)" "unprognostic (8.60e-3)" "unprognostic (1.74e-1)" "unprognostic (9.81e-2)" "unprognostic (2.05e-1)" "unprognostic (7.68e-2)" "unprognostic (1.63e-1)" "unprognostic (1.03e-1)" RAB5IF "C20orf24, PNAS-11, RCAF1, RIP5" ENSG00000101084 "RAB5 interacting factor" Q9BUV8 20 36605779-36612557 "Disease related genes, Predicted membrane proteins" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 222.7" "Cell type enriched" "Detected in many" 5 "Esophageal apical cells: 2431.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Neutrophils_2, Spleen - Neutrophils_2, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057387, HPA076106" Uncertain Supported Mitochondria NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 7: Liver cancer - Metabolism" "Cluster 84: Apical squamous epithelium - Cornification" 10 Mitochondria "HPA057387: , HPA076106: " "unprognostic (1.53e-2)" "unprognostic (1.66e-2)" "unprognostic (2.20e-1)" "unprognostic (1.13e-1)" "unprognostic (6.36e-3)" "unprognostic (1.43e-2)" "unprognostic (3.95e-1)" "unprognostic (1.29e-2)" "unprognostic (2.24e-2)" "validated prognostic unfavorable (1.32e-5)" "validated prognostic unfavorable (7.17e-6)" "unprognostic (1.12e-2)" "potential prognostic unfavorable (4.41e-7)" "potential prognostic unfavorable (1.66e-4)" "unprognostic (2.44e-2)" "unprognostic (1.92e-1)" "unprognostic (1.67e-1)" "unprognostic (6.90e-2)" "unprognostic (2.04e-1)" "unprognostic (4.73e-3)" "unprognostic (1.49e-1)" "unprognostic (5.15e-2)" "unprognostic (1.29e-1)" "unprognostic (2.63e-1)" "unprognostic (2.66e-1)" "unprognostic (1.13e-1)" "unprognostic (1.04e-1)" "unprognostic (1.12e-1)" "potential prognostic unfavorable (1.09e-4)" RAB6A RAB6 ENSG00000175582 "RAB6A, member RAS oncogene family" P20340 11 73675638-73761137 "Predicted intracellular proteins" "ER-Golgi transport, Host-virus interaction, Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009936, HPA059131" Approved Supported "Golgi apparatus,Basal body" NA NA 2300000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 24: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 33 "Golgi apparatus" "Basal body" "CAB009936: , HPA059131: " "unprognostic (1.88e-1)" "unprognostic (1.05e-1)" "unprognostic (1.80e-1)" "unprognostic (9.30e-3)" "unprognostic (8.93e-2)" "unprognostic (2.56e-2)" "unprognostic (1.83e-1)" "unprognostic (3.62e-2)" "unprognostic (1.40e-1)" "potential prognostic unfavorable (7.97e-4)" "potential prognostic favorable (5.87e-7)" "unprognostic (2.02e-2)" "unprognostic (2.27e-1)" "potential prognostic unfavorable (8.93e-4)" "unprognostic (1.79e-1)" "unprognostic (6.38e-3)" "unprognostic (6.83e-3)" "unprognostic (7.02e-2)" "unprognostic (6.82e-2)" "unprognostic (1.34e-1)" "unprognostic (5.76e-2)" "potential prognostic unfavorable (4.84e-4)" "unprognostic (8.94e-2)" "unprognostic (9.21e-2)" "unprognostic (6.42e-2)" "unprognostic (2.08e-2)" "unprognostic (1.23e-2)" "unprognostic (2.43e-1)" "unprognostic (1.32e-1)" "unprognostic (5.55e-2)" "unprognostic (2.08e-1)" RAB6B ENSG00000154917 "RAB6B, member RAS oncogene family" Q9NRW1 3 133824235-133895882 "Enzymes, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 131.0" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 53.2;Brain excitatory neurons: 64.3;Brain inhibitory neurons: 64.4;Choroid plexus epithelial cells: 46.4;Megakaryocytes: 160.7;Oocytes: 73.7;Other brain neurons: 73.8;Platelets: 138.0;Retinal horizontal cells: 46.1;Retinal pigment epithelial cells: 63.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "MAIT T-cell: 7.4" "Lineage enriched" "Detected in single" 47 "T-cells: 7.4" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal medulla cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017713, HPA059131" Uncertain Supported "Golgi apparatus,Basal body" NA NA 2600000 "Cluster 1: T-cells - Unknown function" "Cluster 73: Brain - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 47: Leukemia - Hemostasis" "Cluster 109: Neurons - Neuronal signaling" 24 "Golgi apparatus" "Basal body" "CAB017713: , HPA059131: " "unprognostic (4.81e-2)" "unprognostic (2.00e-3)" "unprognostic (3.24e-1)" "unprognostic (4.83e-3)" "unprognostic (9.71e-2)" "unprognostic (2.04e-1)" "unprognostic (1.76e-1)" "unprognostic (8.19e-3)" "unprognostic (1.83e-2)" "unprognostic (2.49e-1)" "unprognostic (4.50e-3)" "unprognostic (6.74e-3)" "unprognostic (7.34e-2)" "unprognostic (2.88e-3)" "potential prognostic unfavorable (8.27e-6)" "unprognostic (1.18e-1)" "unprognostic (3.49e-1)" "unprognostic (1.53e-2)" "unprognostic (2.65e-2)" "unprognostic (2.12e-1)" "unprognostic (1.44e-1)" "unprognostic (2.36e-3)" "unprognostic (2.56e-1)" "unprognostic (1.13e-1)" "unprognostic (1.92e-1)" "unprognostic (1.77e-1)" "unprognostic (1.25e-2)" "unprognostic (1.24e-2)" "unprognostic (3.30e-2)" "unprognostic (6.44e-2)" "unprognostic (2.30e-2)" RAB6C WTH3 ENSG00000222014 "RAB6C, member RAS oncogene family" Q9H0N0 2 129979666-129982738 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 2.3;parathyroid gland: 3.4" "Group enriched" "Detected in some" 6 "Epicardial cells: 15.9;Oligodendrocytes: 4.5" "Cell type enhanced" "Detected in some" "oligodendrocyte: 5.9" "Cancer enhanced" "Detected in some" "Breast Invasive Carcinoma (TCGA): 1.8;Prostate Adenocarcinoma (TCGA): 3.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "breast cancer: 1.2;prostate cancer: 4.3" "Breast - Breast glandular cells, Prostate - Prostate glandular cells" HPA059131 Uncertain Approved "Golgi apparatus,Basal body" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 11: White matter - Signal transduction" "Cluster 60: Prostate cancer - Unknown function" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 8 "Golgi apparatus" "Basal body" "HPA059131: " "unprognostic (7.40e-2)" "unprognostic (3.32e-1)" "potential prognostic unfavorable (7.61e-4)" "unprognostic (6.18e-2)" RAB6D "RAB6CL, WTH3DI" ENSG00000233087 "RAB6D, member RAS oncogene family" Q53S08 2 131360492-131364168 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "parathyroid gland: 6.6;prostate: 1.7" "Cell type enhanced" "Detected in some" "Colonocytes: 1.5;Early primary spermatocytes: 3.5;Enterocytes: 1.2;Gastric progenitor cells: 1.3;Neuroendocrine cells: 1.5;Paneth cells: 3.9;Prostatic glandular cells: 2.3" "Cancer enhanced" "Detected in some" "Prostate Adenocarcinoma (TCGA): 3.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 1.1;prostate cancer: 1.6" "Prostate - Prostate glandular cells" HPA059131 Uncertain Approved "Golgi apparatus,Basal body" NA NA "Cluster 69: Parathyroid gland - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 3: Early primary spermatocytes - Early meiosis" 1 "Golgi apparatus" "Basal body" "HPA059131: " "unprognostic (1.90e-1)" "unprognostic (9.85e-2)" "unprognostic (4.60e-2)" "potential prognostic unfavorable (7.79e-4)" RAB7A "CMT2B, RAB7" ENSG00000075785 "RAB7A, member RAS oncogene family" P51149 3 128693669-128825942 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Autophagy, Host-virus interaction, Lipid degradation, Lipid metabolism, Protein transport, Transport" Hydrolase "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 2095.2;Neutrophils: 2578.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Macrophages, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006964, CAB037131" Supported Approved "Lysosomes,Primary cilium transition zone,Cytosol" NA NA 3500000 "Cluster 28: Neutrophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 209 "Lysosomes, Primary cilium transition zone" Cytosol "CAB037131: , HPA006964: " "unprognostic (4.23e-1)" "unprognostic (2.63e-3)" "unprognostic (8.19e-2)" "unprognostic (8.13e-3)" "unprognostic (7.55e-2)" "unprognostic (4.01e-2)" "unprognostic (9.06e-2)" "potential prognostic unfavorable (1.07e-4)" "unprognostic (6.41e-2)" "unprognostic (5.15e-2)" "potential prognostic favorable (1.82e-4)" "unprognostic (2.12e-1)" "unprognostic (1.74e-1)" "validated prognostic unfavorable (6.33e-7)" "validated prognostic unfavorable (4.84e-6)" "unprognostic (4.45e-3)" "unprognostic (1.81e-2)" "unprognostic (3.56e-1)" "unprognostic (4.23e-2)" "unprognostic (6.05e-2)" "unprognostic (3.00e-2)" "potential prognostic unfavorable (3.95e-4)" "unprognostic (2.29e-3)" "unprognostic (1.51e-1)" "unprognostic (8.59e-2)" "unprognostic (1.29e-1)" "unprognostic (3.35e-1)" "unprognostic (4.63e-2)" "unprognostic (4.88e-1)" "unprognostic (1.39e-1)" "unprognostic (2.02e-1)" RAB7B "MGC16212, MGC9726" ENSG00000276600 "RAB7B, member RAS oncogene family" Q96AH8 1 205976740-206003461 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 49.2" "Cell type enhanced" "Detected in many" "cDC: 205.3;Cytotrophoblasts: 48.1;Epicardial cells: 138.7;Esophageal basal cells: 54.3;Esophageal suprabasal cells: 33.0;Fibro-adipogenic progenitors: 39.8;Macrophages: 41.9;Mesothelial cells: 37.7;Suprabasal keratinocytes: 32.5" "Cell type enhanced" "Detected in some" "committed oligodendrocyte precursor: 10.4;fibroblast: 20.1;oligodendrocyte: 20.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "myeloid DC: 5.1" "Lineage enriched" "Detected in single" 8 "dendritic cells: 5.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 58: Skin - Keratinization" "Cluster 30: White matter - Myelination" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 82: Dendritic cells - Antigen presentation" 5 "unprognostic (6.78e-2)" "unprognostic (5.73e-2)" "unprognostic (1.93e-1)" "unprognostic (1.07e-1)" "unprognostic (3.51e-1)" "unprognostic (3.41e-2)" "unprognostic (8.40e-2)" "unprognostic (1.38e-1)" "unprognostic (3.42e-1)" "unprognostic (2.64e-1)" "unprognostic (1.51e-1)" "unprognostic (1.24e-3)" "unprognostic (9.35e-2)" "unprognostic (3.20e-2)" "unprognostic (1.51e-1)" "unprognostic (1.09e-2)" "potential prognostic unfavorable (4.75e-4)" "unprognostic (1.92e-2)" "unprognostic (4.30e-2)" "unprognostic (1.49e-2)" "unprognostic (1.36e-2)" "unprognostic (7.34e-2)" "unprognostic (4.72e-2)" "unprognostic (1.77e-1)" "unprognostic (3.07e-2)" "potential prognostic unfavorable (2.04e-4)" RAB8A "MEL, RAB8" ENSG00000167461 "RAB8A, member RAS oncogene family" P61006 19 16111889-16134234 "Enzymes, Predicted intracellular proteins" "Autophagy, Cilium biogenesis/degradation, Protein transport, Transport" Hydrolase Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Megakaryocyte progenitors: 189.7;Megakaryocytes: 364.7;Platelets: 660.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Colon - Macrophages, Skin - Keratinocyte (other), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041945 Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Plasma membrane,Primary cilium,Centriolar satellite,Basal body,Cytosol" No No 5300000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 77: Intestine - Digestion" "Cluster 21: Non-specific - Metabolism" "Cluster 23: Non-specific - Transcription" "Cluster 47: Platelets - Hemostasis" 52 "Nucleoplasm, Nucleoli, Plasma membrane" "Golgi apparatus, Primary cilium, Centriolar satellite, Basal body, Cytosol" "HPA041945: " "unprognostic (6.59e-2)" "unprognostic (1.61e-1)" "unprognostic (2.93e-1)" "unprognostic (2.29e-1)" "unprognostic (1.01e-1)" "unprognostic (1.68e-1)" "unprognostic (4.35e-1)" "unprognostic (2.75e-1)" "unprognostic (2.95e-1)" "unprognostic (2.37e-2)" "unprognostic (2.05e-3)" "unprognostic (1.83e-1)" "unprognostic (1.47e-1)" "unprognostic (1.96e-2)" "unprognostic (1.86e-2)" "unprognostic (6.36e-3)" "unprognostic (8.19e-2)" "unprognostic (2.04e-1)" "unprognostic (2.42e-3)" "unprognostic (3.26e-1)" "unprognostic (5.66e-2)" "unprognostic (4.53e-3)" "unprognostic (1.81e-1)" "unprognostic (1.63e-3)" "unprognostic (3.11e-1)" "unprognostic (8.96e-2)" "unprognostic (1.93e-1)" "unprognostic (2.15e-1)" "unprognostic (1.42e-1)" "unprognostic (1.79e-1)" "unprognostic (1.68e-1)" RAB8B ENSG00000166128 "RAB8B, member RAS oncogene family" Q92930 15 63189560-63267776 "Predicted intracellular proteins" "Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 76.5" "Cell type enhanced" "Detected in many" "cDC: 405.3;Innate lymphoid cells: 442.8;Late spermatids: 617.2;monocytes: 381.0;Neutrophil progenitors: 573.5;Neutrophils: 1695.9;NK-cells: 568.0" "Cell type enhanced" "Detected in all" "leukocyte: 374.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Skin - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 5200000 "Cluster 35: Neutrophils - Protein binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 21: Non-specific - Metabolism" "Cluster 55: Lymphoma - Immune response" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 21 "unprognostic (1.46e-2)" "unprognostic (3.23e-1)" "unprognostic (1.07e-2)" "unprognostic (4.68e-2)" "unprognostic (2.52e-1)" "unprognostic (4.92e-2)" "unprognostic (1.76e-1)" "unprognostic (8.58e-2)" "unprognostic (1.61e-1)" "unprognostic (1.45e-1)" "potential prognostic favorable (2.95e-5)" "unprognostic (2.14e-2)" "unprognostic (3.33e-1)" "unprognostic (1.35e-2)" "unprognostic (2.06e-1)" "unprognostic (8.62e-2)" "unprognostic (1.32e-2)" "unprognostic (7.14e-3)" "unprognostic (2.31e-2)" "unprognostic (2.45e-3)" "unprognostic (2.23e-3)" "unprognostic (2.65e-2)" "unprognostic (9.56e-2)" "unprognostic (1.09e-1)" "unprognostic (1.44e-1)" "unprognostic (2.63e-2)" "unprognostic (3.25e-1)" "unprognostic (3.57e-2)" "unprognostic (1.57e-1)" "unprognostic (4.72e-2)" "unprognostic (9.51e-3)" RAB9A RAB9 ENSG00000123595 "RAB9A, member RAS oncogene family" P51151 X 13689128-13710504 "Predicted intracellular proteins" "Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 296.2;Syncytiotrophoblasts: 502.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003094, CAB016411" Supported Uncertain Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 107 Nucleoplasm Cytosol "CAB016411: , HPA003094: " "unprognostic (8.88e-2)" "unprognostic (3.03e-2)" "unprognostic (1.65e-1)" "unprognostic (2.59e-1)" "potential prognostic favorable (1.32e-4)" "unprognostic (1.15e-2)" "unprognostic (2.36e-1)" "unprognostic (2.83e-3)" "unprognostic (1.55e-1)" "unprognostic (4.13e-2)" "potential prognostic favorable (4.49e-10)" "unprognostic (6.77e-2)" "unprognostic (1.02e-1)" "unprognostic (3.85e-2)" "unprognostic (2.02e-2)" "unprognostic (1.00e-1)" "unprognostic (2.62e-1)" "unprognostic (3.70e-2)" "unprognostic (7.12e-2)" "unprognostic (2.01e-1)" "unprognostic (3.01e-1)" "potential prognostic unfavorable (3.18e-4)" "unprognostic (2.53e-1)" "unprognostic (5.49e-1)" "unprognostic (1.15e-2)" "unprognostic (1.16e-1)" "unprognostic (6.60e-3)" "unprognostic (2.77e-1)" "unprognostic (1.15e-1)" "unprognostic (2.73e-1)" "unprognostic (5.12e-2)" RAB9B RAB9L ENSG00000123570 "RAB9B, member RAS oncogene family" Q9NP90 X 103822327-103832257 "Predicted intracellular proteins" "Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 20.1" "Group enriched" "Detected in some" 4 "Loop of henle epithelial cells: 1.1;Podocytes: 3.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 4.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney cancer: 3.8" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061932 Approved NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 105: Non-specific - Mixed function" 6 "HPA061932: " "unprognostic (2.76e-2)" "unprognostic (2.06e-1)" "unprognostic (2.46e-1)" "potential prognostic favorable (4.08e-5)" "unprognostic (2.38e-2)" "unprognostic (1.54e-1)" "unprognostic (2.77e-3)" "unprognostic (2.54e-3)" "unprognostic (3.21e-1)" "unprognostic (8.35e-2)" "unprognostic (4.34e-3)" "unprognostic (1.71e-2)" "unprognostic (2.12e-1)" RABAC1 "PRA1, PRAF1, YIP3" ENSG00000105404 "Rab acceptor 1" Q9UI14 19 41956681-41959321 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 631.2;Extravillous trophoblasts: 661.1;Late spermatids: 1139.2;Plasma cells: 712.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019320, HPA029171" Supported NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 74: Non-specific - Signal transduction" "Cluster 45: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 8: Non-specific - Secretory pathway" 88 "CAB019320: , HPA029171: " "unprognostic (6.93e-3)" "unprognostic (6.75e-2)" "unprognostic (8.66e-3)" "unprognostic (4.37e-3)" "unprognostic (6.46e-2)" "unprognostic (1.49e-1)" "unprognostic (2.04e-1)" "unprognostic (4.74e-1)" "unprognostic (4.90e-2)" "unprognostic (2.71e-1)" "unprognostic (7.06e-2)" "unprognostic (6.45e-2)" "unprognostic (5.55e-2)" "unprognostic (1.48e-1)" "unprognostic (2.91e-2)" "unprognostic (1.03e-1)" "unprognostic (3.01e-1)" "unprognostic (1.09e-1)" "unprognostic (5.62e-2)" "unprognostic (6.16e-3)" "unprognostic (1.39e-2)" "unprognostic (2.94e-3)" "unprognostic (4.19e-3)" "unprognostic (1.23e-1)" "unprognostic (4.08e-2)" "unprognostic (2.76e-1)" "unprognostic (1.48e-1)" "unprognostic (6.45e-2)" "unprognostic (1.12e-1)" "unprognostic (5.23e-2)" "unprognostic (1.73e-1)" RABEP1 "neurocrescin, RAB5EP, rabaptin-5, RABPT5" ENSG00000029725 "Rabaptin, RAB GTPase binding effector protein 1" Q15276 17 5282265-5386340 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, Endocytosis, Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004549, HPA019669, HPA024235, HPA024691" Supported Supported Vesicles,Cytosol NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 79 "Vesicles, Cytosol" "CAB004549: , HPA019669: , HPA024235: , HPA024691: " "unprognostic (2.83e-2)" "unprognostic (1.00e-1)" "unprognostic (3.88e-2)" "unprognostic (1.02e-1)" "unprognostic (7.30e-2)" "unprognostic (2.69e-1)" "unprognostic (3.10e-1)" "unprognostic (2.72e-2)" "unprognostic (2.34e-2)" "potential prognostic unfavorable (2.05e-4)" "potential prognostic favorable (7.98e-4)" "unprognostic (1.73e-2)" "unprognostic (4.34e-2)" "unprognostic (2.39e-1)" "unprognostic (5.51e-2)" "unprognostic (1.92e-1)" "unprognostic (2.76e-1)" "unprognostic (1.23e-1)" "unprognostic (1.76e-1)" "unprognostic (3.75e-1)" "unprognostic (1.89e-2)" "unprognostic (3.03e-2)" "unprognostic (6.44e-2)" "unprognostic (2.92e-1)" "unprognostic (9.00e-2)" "unprognostic (1.15e-1)" "unprognostic (2.47e-2)" "unprognostic (1.20e-1)" "unprognostic (8.07e-2)" "unprognostic (9.55e-2)" "unprognostic (1.68e-1)" RABEP2 "FLJ23282, FRA" ENSG00000177548 "Rabaptin, RAB GTPase binding effector protein 2" Q9H5N1 16 28904421-28936526 "Predicted intracellular proteins" "Cilium biogenesis/degradation, Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 125.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Prostate - Prostate glandular cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047641 Approved Supported "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 18: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 13 Cytosol "Golgi apparatus, Vesicles" "HPA047641: " "unprognostic (3.59e-1)" "unprognostic (2.05e-2)" "unprognostic (3.44e-1)" "unprognostic (2.58e-1)" "unprognostic (6.56e-2)" "unprognostic (1.74e-2)" "unprognostic (4.63e-1)" "unprognostic (9.69e-3)" "potential prognostic favorable (7.99e-4)" "unprognostic (3.06e-2)" "unprognostic (3.07e-3)" "unprognostic (2.31e-1)" "potential prognostic favorable (4.25e-6)" "unprognostic (9.90e-2)" "unprognostic (4.88e-2)" "unprognostic (1.88e-2)" "unprognostic (2.10e-1)" "unprognostic (8.29e-2)" "unprognostic (1.01e-1)" "unprognostic (1.19e-1)" "unprognostic (1.68e-1)" "unprognostic (2.23e-2)" "unprognostic (1.92e-1)" "unprognostic (1.07e-1)" "unprognostic (2.38e-2)" "unprognostic (1.84e-1)" "unprognostic (9.39e-2)" "unprognostic (3.18e-1)" "unprognostic (1.04e-1)" "unprognostic (1.78e-1)" "unprognostic (1.14e-1)" RABEPK "bA65N13.1, RAB9P40" ENSG00000136933 "Rab9 effector protein with kelch motifs" Q7Z6M1 9 125200542-125234161 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 109.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023920, HPA024415" Supported Supported Vesicles NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 36: Brain & Liver - Signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 65: Non-specific - Cell growth & division" 3 Vesicles "HPA023920: , HPA024415: " "unprognostic (2.49e-1)" "unprognostic (3.12e-2)" "unprognostic (1.28e-2)" "unprognostic (6.80e-3)" "unprognostic (2.00e-1)" "unprognostic (5.96e-3)" "unprognostic (3.89e-2)" "unprognostic (3.71e-2)" "unprognostic (6.57e-3)" "unprognostic (4.19e-1)" "unprognostic (1.52e-3)" "unprognostic (7.02e-2)" "unprognostic (1.29e-2)" "unprognostic (3.44e-2)" "unprognostic (3.15e-1)" "unprognostic (1.23e-2)" "unprognostic (1.19e-3)" "unprognostic (6.59e-2)" "unprognostic (1.33e-2)" "unprognostic (3.34e-1)" "unprognostic (7.43e-2)" "unprognostic (2.18e-1)" "unprognostic (1.09e-1)" "unprognostic (3.14e-1)" "unprognostic (1.11e-2)" "unprognostic (2.86e-1)" "unprognostic (8.29e-2)" "unprognostic (4.34e-1)" "unprognostic (1.28e-1)" "unprognostic (2.93e-2)" "unprognostic (1.04e-2)" RABGAP1 "GAPCenA, TBC1D11" ENSG00000011454 "RAB GTPase activating protein 1" Q9Y3P9 9 122940833-123104866 "Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064860, HPA072273" Enhanced Enhanced Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 22 Cytosol "HPA064860: , HPA072273: " "unprognostic (1.62e-1)" "unprognostic (3.28e-3)" "unprognostic (1.81e-1)" "unprognostic (2.98e-2)" "unprognostic (2.10e-1)" "unprognostic (6.33e-3)" "unprognostic (1.48e-2)" "unprognostic (3.06e-3)" "unprognostic (9.92e-2)" "unprognostic (4.08e-1)" "validated prognostic favorable (5.57e-8)" "validated prognostic favorable (1.19e-4)" "unprognostic (4.35e-2)" "unprognostic (1.28e-1)" "unprognostic (1.34e-1)" "unprognostic (6.42e-2)" "unprognostic (9.84e-2)" "unprognostic (8.17e-3)" "unprognostic (4.34e-3)" "unprognostic (4.52e-2)" "unprognostic (2.94e-3)" "unprognostic (2.13e-2)" "unprognostic (1.56e-1)" "unprognostic (1.23e-1)" "unprognostic (2.55e-1)" "unprognostic (1.23e-1)" "unprognostic (1.24e-1)" "unprognostic (2.28e-1)" "unprognostic (2.52e-1)" "unprognostic (5.08e-2)" "unprognostic (1.14e-1)" RABGAP1L "FLJ38519, HHL, KIAA0471, TBC1D18" ENSG00000152061 "RAB GTPase activating protein 1 like" "B7ZAP0, Q5R372" 1 174159410-174995308 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Endocytosis, Protein transport, Transport" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 114.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 1614.3;Choroid plexus epithelial cells: 1940.8;pDCs: 2128.2;Podocytes: 1591.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "lymphoma: 94.0" "Heart muscle - Cardiomyocytes, Prostate - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054695 Uncertain NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 35: Non-specific - Mixed function" "Cluster 5: Non-specific - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 13 "HPA054695: " "unprognostic (3.46e-2)" "unprognostic (4.92e-2)" "unprognostic (3.48e-2)" "unprognostic (1.28e-1)" "unprognostic (1.43e-2)" "unprognostic (5.54e-2)" "unprognostic (1.78e-1)" "unprognostic (4.74e-3)" "unprognostic (7.19e-3)" "unprognostic (4.59e-3)" "unprognostic (1.76e-2)" "unprognostic (2.99e-1)" "unprognostic (2.37e-2)" "unprognostic (1.87e-2)" "unprognostic (1.37e-1)" "unprognostic (2.56e-2)" "unprognostic (1.77e-1)" "unprognostic (4.01e-2)" "unprognostic (9.47e-2)" "unprognostic (1.76e-1)" "unprognostic (3.26e-2)" "unprognostic (5.12e-3)" "unprognostic (2.74e-1)" "unprognostic (2.96e-1)" "unprognostic (1.51e-1)" "unprognostic (2.92e-2)" "unprognostic (6.34e-2)" "unprognostic (2.91e-1)" "unprognostic (2.15e-1)" "unprognostic (1.33e-2)" "unprognostic (4.22e-1)" RABGEF1 "rabex-5, RABEX5" ENSG00000154710 "RAB guanine nucleotide exchange factor 1" Q9UJ41 7 66682164-66811464 "Predicted intracellular proteins, Transporters" "Endocytosis, Protein transport, Transport, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 72.6" "Group enriched" "Detected in many" 4 "Astrocytes: 188.8;Bergmann glia: 177.2;Brain excitatory neurons: 195.5;Brain inhibitory neurons: 208.7;Choroid plexus epithelial cells: 294.5;Ependymal cells: 158.0;Microglia: 146.2;Oligodendrocyte progenitor cells: 170.5;Oligodendrocytes: 328.0;Other brain neurons: 228.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001407 Supported Nucleoli,Cytosol NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 40: Non-specific - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 22: Non-specific - Basic cellular functions" 39 Cytosol Nucleoli "HPA001407: " "unprognostic (1.25e-1)" "unprognostic (3.58e-1)" "unprognostic (1.19e-2)" "unprognostic (1.23e-2)" "unprognostic (7.04e-2)" "unprognostic (1.65e-1)" "unprognostic (6.58e-2)" "unprognostic (1.08e-1)" "unprognostic (2.09e-1)" "unprognostic (5.08e-2)" "potential prognostic favorable (4.86e-4)" "unprognostic (3.67e-1)" "unprognostic (1.42e-1)" "unprognostic (1.90e-3)" "unprognostic (1.06e-3)" "unprognostic (1.47e-3)" "unprognostic (1.77e-1)" "unprognostic (2.74e-1)" "unprognostic (1.59e-1)" "potential prognostic unfavorable (1.25e-4)" "unprognostic (1.19e-1)" "validated prognostic unfavorable (3.48e-5)" "validated prognostic unfavorable (5.58e-4)" "unprognostic (2.84e-2)" "unprognostic (2.85e-1)" "unprognostic (5.08e-2)" "unprognostic (1.29e-1)" "unprognostic (9.08e-3)" "unprognostic (2.79e-1)" "unprognostic (6.74e-2)" "unprognostic (3.27e-2)" RABGGTA PTAR3 ENSG00000100949 "Rab geranylgeranyltransferase subunit alpha" Q92696 14 24265538-24271611 "Enzymes, Essential proteins, Predicted intracellular proteins" "Prenyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 63.4" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 201.6;Esophageal suprabasal cells: 77.8;Syncytiotrophoblasts: 51.6;Undifferentiated spermatogonia: 42.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043488 Approved NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 45: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 85: Squamous epithelial cells - Keratinization" 59 "HPA043488: " "unprognostic (1.69e-2)" "unprognostic (3.30e-2)" "unprognostic (1.79e-1)" "unprognostic (1.40e-1)" "unprognostic (2.34e-3)" "unprognostic (1.15e-1)" "unprognostic (2.06e-1)" "unprognostic (3.83e-1)" "unprognostic (1.18e-1)" "unprognostic (8.28e-3)" "potential prognostic favorable (3.40e-5)" "unprognostic (1.53e-1)" "unprognostic (1.74e-3)" "unprognostic (1.16e-2)" "unprognostic (2.37e-2)" "unprognostic (1.41e-1)" "unprognostic (6.54e-2)" "unprognostic (1.27e-1)" "unprognostic (4.23e-1)" "unprognostic (2.42e-2)" "unprognostic (2.20e-2)" "unprognostic (7.34e-2)" "unprognostic (1.12e-1)" "unprognostic (1.53e-1)" "unprognostic (3.85e-2)" "unprognostic (6.42e-2)" "unprognostic (7.08e-3)" "unprognostic (1.04e-1)" "unprognostic (1.80e-1)" "potential prognostic favorable (8.66e-4)" "unprognostic (1.67e-1)" RABGGTB ENSG00000137955 "Rab geranylgeranyltransferase subunit beta" P53611 1 75786197-75795086 "Enzymes, Essential proteins, Predicted intracellular proteins" "Prenyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "HPA026585, HPA027167, HPA030793" Approved Supported Approved Vesicles NA NA 11000 "Cluster 18: Non-specific - Translation" "Cluster 76: Non-specific - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 97: Non-specific - Cellular respiration" 33 Vesicles "HPA026585: , HPA027167: , HPA030793: " "unprognostic (3.22e-1)" "unprognostic (2.94e-2)" "unprognostic (1.40e-2)" "unprognostic (1.74e-1)" "unprognostic (1.20e-2)" "unprognostic (2.57e-1)" "unprognostic (1.01e-1)" "unprognostic (1.30e-2)" "unprognostic (7.26e-3)" "potential prognostic unfavorable (1.27e-4)" "potential prognostic favorable (4.63e-7)" "unprognostic (2.19e-3)" "unprognostic (7.60e-3)" "potential prognostic unfavorable (2.57e-4)" "unprognostic (1.26e-3)" "unprognostic (2.27e-1)" "unprognostic (1.77e-1)" "unprognostic (2.09e-1)" "unprognostic (1.30e-1)" "unprognostic (2.27e-1)" "unprognostic (1.56e-1)" "unprognostic (3.23e-1)" "unprognostic (3.39e-2)" "unprognostic (1.17e-1)" "unprognostic (7.67e-3)" "unprognostic (3.54e-2)" "unprognostic (1.12e-1)" "unprognostic (1.12e-1)" "unprognostic (1.18e-1)" "unprognostic (6.37e-2)" "unprognostic (3.14e-1)" RABIF "mss4, RASGRF3" ENSG00000183155 "RAB interacting factor" P47224 1 202878282-202889149 "Predicted intracellular proteins" "Protein transport, Transport" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 7 "Late spermatids: 5434.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027715, HPA054936" Approved Approved "Microtubules,Cytokinetic bridge" Yes NA "Cluster 25: Non-specific - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 53: Neurons - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 44 "Microtubules, Cytokinetic bridge" "HPA027715: , HPA054936: " "unprognostic (2.86e-2)" "unprognostic (7.02e-3)" "unprognostic (2.07e-1)" "unprognostic (1.18e-1)" "unprognostic (8.97e-2)" "unprognostic (2.95e-1)" "unprognostic (4.85e-1)" "unprognostic (1.88e-2)" "unprognostic (1.56e-2)" "unprognostic (2.66e-3)" "unprognostic (8.82e-3)" "unprognostic (2.00e-1)" "unprognostic (6.64e-3)" "potential prognostic unfavorable (2.60e-4)" "unprognostic (3.73e-2)" "unprognostic (8.40e-2)" "unprognostic (1.71e-1)" "unprognostic (3.75e-2)" "unprognostic (4.34e-2)" "unprognostic (6.23e-2)" "unprognostic (1.14e-2)" "unprognostic (2.24e-2)" "unprognostic (1.94e-1)" "unprognostic (7.43e-2)" "unprognostic (2.76e-2)" "unprognostic (2.17e-3)" "unprognostic (1.79e-3)" "unprognostic (1.11e-1)" "unprognostic (5.44e-2)" "unprognostic (2.14e-1)" "unprognostic (3.26e-1)" RABL2A ENSG00000144134 "RAB, member of RAS oncogene family like 2A" Q9UBK7 2 113627229-113643396 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 20.1" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 124.7;Endometrial ciliated cells: 88.1;Ependymal cells: 222.8;Epididymal efferent duct ciliated cells: 91.5;Epididymal principal cells: 75.0;Fallopian tube ciliated cells: 159.4;Respiratory ciliated cells: 207.9" "Cell type enhanced" "Detected in all" "ependymal cell: 247.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Lung - Respiratory ciliated cells, Testis - Early spermatids" "HPA042642, HPA042700, HPA044007" Approved Approved "Vesicles,Centrosome,Basal body" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" 4 "Centrosome, Basal body" Vesicles "HPA042642: , HPA042700: , HPA044007: " "unprognostic (2.22e-2)" "unprognostic (1.29e-1)" "unprognostic (5.22e-2)" "potential prognostic favorable (3.49e-4)" "unprognostic (1.12e-1)" "unprognostic (2.51e-1)" "unprognostic (6.14e-2)" "unprognostic (3.63e-1)" "unprognostic (3.48e-2)" "potential prognostic favorable (2.34e-6)" "unprognostic (3.76e-3)" "unprognostic (2.18e-1)" "unprognostic (3.03e-2)" "unprognostic (1.71e-2)" "unprognostic (3.63e-1)" "unprognostic (8.06e-2)" "unprognostic (4.65e-2)" "unprognostic (1.66e-1)" "unprognostic (5.38e-2)" "unprognostic (7.09e-2)" "unprognostic (2.68e-3)" "unprognostic (7.60e-2)" "unprognostic (1.06e-1)" "unprognostic (2.75e-1)" "unprognostic (1.27e-1)" "unprognostic (2.50e-1)" "unprognostic (1.80e-1)" "unprognostic (5.01e-2)" "unprognostic (1.79e-1)" RABL2B ENSG00000079974 "RAB, member of RAS oncogene family like 2B" Q9UNT1 22 50767501-50783667 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 84.8" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 135.5;Ependymal cells: 95.2;Epididymal efferent duct ciliated cells: 124.7;Fallopian tube ciliated cells: 192.2;Respiratory ciliated cells: 248.2" "Cell type enhanced" "Detected in all" "ependymal cell: 99.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells" "HPA042642, HPA042700, HPA044007" Approved Supported "Vesicles,Centrosome,Basal body" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 22: Epididymis - Mixed function" "Cluster 17: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" 4 "Centrosome, Basal body" Vesicles "HPA042642: , HPA042700: , HPA044007: " "unprognostic (1.95e-2)" "unprognostic (1.35e-1)" "unprognostic (5.08e-2)" "unprognostic (3.82e-2)" "unprognostic (3.92e-1)" "unprognostic (3.90e-2)" "unprognostic (1.03e-2)" "unprognostic (1.12e-1)" "unprognostic (2.71e-1)" "unprognostic (7.09e-2)" "unprognostic (9.56e-2)" "unprognostic (2.02e-1)" "unprognostic (8.31e-2)" "potential prognostic unfavorable (6.36e-4)" "unprognostic (6.94e-2)" "unprognostic (2.81e-1)" "unprognostic (1.70e-1)" "unprognostic (1.20e-1)" "unprognostic (5.18e-2)" "unprognostic (1.08e-1)" "unprognostic (1.15e-1)" "unprognostic (3.09e-2)" "unprognostic (1.09e-2)" "unprognostic (7.99e-2)" "unprognostic (6.22e-3)" "unprognostic (1.12e-1)" "unprognostic (3.17e-1)" "unprognostic (2.75e-2)" "unprognostic (2.44e-1)" "unprognostic (3.72e-2)" "unprognostic (8.87e-3)" RABL3 MGC23920 ENSG00000144840 "RAB, member of RAS oncogene family like 3" Q5HYI8 3 120684938-120742993 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 200.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035150, HPA035151, HPA069861" Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 38: Non-specific - Transcription" "Cluster 79: Photoreceptor cells - Phototransduction" 32 "Endoplasmic reticulum" "HPA035150: , HPA035151: , HPA069861: " "unprognostic (1.00e-1)" "unprognostic (7.29e-3)" "unprognostic (7.90e-2)" "unprognostic (2.03e-1)" "unprognostic (2.52e-2)" "unprognostic (1.22e-1)" "unprognostic (2.79e-1)" "potential prognostic unfavorable (2.74e-4)" "unprognostic (2.62e-1)" "unprognostic (8.04e-2)" "potential prognostic favorable (9.68e-8)" "unprognostic (1.38e-3)" "unprognostic (2.96e-2)" "unprognostic (1.03e-1)" "unprognostic (3.32e-2)" "unprognostic (1.18e-1)" "unprognostic (8.33e-2)" "unprognostic (1.62e-2)" "unprognostic (6.09e-3)" "unprognostic (1.74e-1)" "unprognostic (2.75e-3)" "unprognostic (9.22e-2)" "unprognostic (2.18e-3)" "unprognostic (3.36e-1)" "unprognostic (3.71e-2)" "unprognostic (1.80e-1)" "unprognostic (7.80e-2)" "unprognostic (1.56e-1)" "unprognostic (3.41e-1)" "unprognostic (1.55e-1)" "unprognostic (2.79e-2)" RABL6 "bA216L13.9, C9orf86, FLJ10101, FLJ13045, Parf, pp8875, RBEL1" ENSG00000196642 "RAB, member RAS oncogene family like 6" Q3YEC7 9 136807943-136841187 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044037 Uncertain Supported "Centriolar satellite,Centrosome,Basal body,Cytosol" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 65: Non-specific - Cell growth & division" 13 "Centrosome, Cytosol" "Centriolar satellite, Basal body" "HPA044037: " "unprognostic (5.69e-2)" "unprognostic (1.03e-2)" "unprognostic (6.18e-2)" "unprognostic (6.19e-2)" "unprognostic (1.51e-1)" "unprognostic (7.85e-2)" "potential prognostic favorable (2.74e-4)" "unprognostic (4.03e-1)" "unprognostic (2.98e-1)" "unprognostic (2.97e-3)" "unprognostic (4.12e-2)" "potential prognostic favorable (1.31e-4)" "unprognostic (2.17e-3)" "unprognostic (3.43e-2)" "unprognostic (5.35e-2)" "unprognostic (1.05e-2)" "unprognostic (1.89e-2)" "unprognostic (2.00e-1)" "unprognostic (1.28e-1)" "unprognostic (2.36e-3)" "unprognostic (1.42e-1)" "unprognostic (1.63e-2)" "unprognostic (1.05e-1)" "unprognostic (1.64e-1)" "unprognostic (9.36e-3)" "unprognostic (4.85e-2)" "unprognostic (8.32e-2)" "unprognostic (7.06e-2)" "unprognostic (1.27e-2)" RAC1 "p21-Rac1, Rac-1, TC-25" ENSG00000136238 "Rac family small GTPase 1" P63000 7 6374527-6403967 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" Hydrolase "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 6771.9;Esophageal suprabasal cells: 2039.8;Gastric progenitor cells: 1777.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB035994, HPA047820" Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA 3400000 "Cluster 7: Non-specific - Innate immune response" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 84: Apical squamous epithelium - Cornification" 220 "Nucleoplasm, Cytosol" Nucleoli "CAB035994: , HPA047820: " "unprognostic (7.44e-2)" "unprognostic (3.14e-2)" "potential prognostic unfavorable (2.03e-4)" "unprognostic (2.19e-1)" "unprognostic (1.53e-1)" "unprognostic (2.41e-1)" "unprognostic (1.58e-2)" "unprognostic (1.20e-3)" "unprognostic (1.25e-2)" "unprognostic (4.46e-3)" "unprognostic (1.36e-2)" "unprognostic (9.96e-3)" "unprognostic (3.09e-2)" "validated prognostic unfavorable (1.12e-5)" "validated prognostic unfavorable (2.76e-5)" "potential prognostic unfavorable (6.87e-6)" "unprognostic (6.29e-3)" "unprognostic (2.20e-1)" "unprognostic (2.70e-2)" "unprognostic (8.72e-2)" "unprognostic (2.57e-3)" "potential prognostic unfavorable (1.16e-4)" "unprognostic (7.07e-2)" "unprognostic (5.64e-2)" "unprognostic (3.21e-1)" "unprognostic (9.53e-2)" "unprognostic (1.20e-1)" "unprognostic (1.87e-1)" "unprognostic (6.45e-3)" "unprognostic (4.42e-1)" "unprognostic (1.79e-1)" RAC2 EN-7 ENSG00000128340 "Rac family small GTPase 2" P15153 22 37225270-37259594 "Disease related genes, Human disease related genes, Predicted intracellular proteins, RAS pathway related proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 389.1;lymphoid tissue: 362.6" "Cell type enhanced" "Detected in many" "B-cells: 198.0;Hofbauer cells: 170.8;Mast cells: 462.9;Megakaryocyte progenitors: 216.3;Megakaryocyte-Erythroid progenitors: 154.8;Megakaryocytes: 321.4;Monocyte progenitors: 223.3;monocytes: 170.9;Neutrophil progenitors: 399.4;Neutrophils: 768.3;NK-cells: 319.9;pDCs: 243.4;Plasma cells: 190.9;T-cells: 245.8" "Cell type enriched" "Detected in some" 21 "leukocyte: 173.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 381.1;lymphoma: 371.0" "Breast - T-cells, Prostate - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022946, HPA047820" Enhanced NA Yes 4400000 "Cluster 35: Neutrophils - Protein binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 49: HMC-1 - Innate immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 18 "CAB022946: , HPA047820: " "unprognostic (3.51e-2)" "potential prognostic favorable (2.47e-4)" "unprognostic (1.54e-2)" "unprognostic (2.66e-1)" "unprognostic (1.90e-1)" "unprognostic (4.54e-2)" "potential prognostic unfavorable (1.53e-4)" "unprognostic (2.59e-2)" "unprognostic (5.23e-2)" "unprognostic (2.28e-1)" "unprognostic (1.32e-2)" "unprognostic (2.33e-1)" "unprognostic (4.01e-2)" "unprognostic (4.03e-1)" "unprognostic (1.95e-1)" "unprognostic (1.75e-1)" "unprognostic (3.68e-2)" "unprognostic (1.91e-2)" "unprognostic (2.71e-2)" "unprognostic (2.25e-1)" "unprognostic (2.88e-1)" "unprognostic (1.89e-2)" "potential prognostic unfavorable (2.76e-4)" "unprognostic (4.87e-1)" "unprognostic (1.36e-1)" "unprognostic (5.85e-2)" "unprognostic (1.12e-2)" "unprognostic (1.76e-1)" "unprognostic (1.25e-1)" "unprognostic (1.27e-2)" "unprognostic (5.49e-2)" RAC3 ENSG00000169750 "Rac family small GTPase 3" P60763 17 82031678-82034204 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" Hydrolase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 68.0" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 44.7;Extravillous trophoblasts: 215.9;Migrating cytotrophoblasts: 45.6;Undifferentiated spermatogonia: 85.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047820 Uncertain NA NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 1: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 23 "HPA047820: " "unprognostic (1.93e-2)" "unprognostic (4.54e-2)" "unprognostic (4.25e-2)" "unprognostic (1.49e-1)" "unprognostic (4.70e-2)" "unprognostic (1.78e-1)" "unprognostic (9.60e-2)" "unprognostic (4.51e-2)" "unprognostic (1.91e-1)" "unprognostic (1.07e-2)" "potential prognostic unfavorable (6.22e-5)" "unprognostic (4.04e-2)" "unprognostic (2.29e-2)" "unprognostic (7.45e-3)" "unprognostic (3.52e-2)" "unprognostic (2.76e-2)" "unprognostic (2.60e-2)" "unprognostic (9.68e-2)" "unprognostic (8.74e-3)" "unprognostic (4.80e-2)" "unprognostic (3.26e-3)" "unprognostic (4.48e-2)" "unprognostic (7.96e-3)" "unprognostic (3.18e-1)" "unprognostic (1.06e-1)" "unprognostic (4.52e-3)" "unprognostic (1.05e-1)" "unprognostic (1.95e-1)" "unprognostic (3.02e-1)" "potential prognostic unfavorable (6.82e-7)" "unprognostic (2.33e-1)" RACGAP1 "CYK4, MgcRacGAP" ENSG00000161800 "Rac GTPase activating protein 1" Q9H0H5 12 49976923-50033136 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Ion transport, Spermatogenesis, Transport" "Developmental protein, GTPase activation" "Congenital dyserythropoietic anemia, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 36.7;lymphoid tissue: 40.0;testis: 42.5" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 89.8;Erythrocyte progenitors: 76.0;Extravillous trophoblasts: 63.2;Gastric progenitor cells: 51.3;Late primary spermatocytes: 53.4;Monocyte progenitors: 105.7;Neutrophil progenitors: 66.2;Renal collecting duct intercalated cells: 49.4" "Cell type enhanced" "Detected in all" "Bergmann glia: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025859, HPA039427, HPA043912" Enhanced Enhanced Nucleoplasm Yes Yes "Cluster 32: Basophils - Transcription" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 27: Non-specific - Cell proliferation" 56 Nucleoplasm "CAB025859: , HPA039427: , HPA043912: " "unprognostic (3.32e-2)" "unprognostic (1.00e-3)" "unprognostic (7.38e-3)" "unprognostic (1.01e-1)" "unprognostic (1.78e-2)" "unprognostic (1.41e-1)" "unprognostic (1.87e-1)" "unprognostic (9.45e-2)" "unprognostic (1.10e-1)" "potential prognostic unfavorable (1.30e-5)" "unprognostic (7.48e-3)" "potential prognostic unfavorable (5.95e-4)" "potential prognostic unfavorable (4.71e-4)" "validated prognostic unfavorable (2.74e-6)" "validated prognostic unfavorable (3.27e-7)" "validated prognostic unfavorable (2.07e-6)" "validated prognostic unfavorable (3.33e-4)" "unprognostic (1.67e-2)" "unprognostic (2.17e-1)" "unprognostic (4.16e-2)" "unprognostic (1.30e-1)" "potential prognostic unfavorable (2.07e-4)" "unprognostic (7.67e-3)" "unprognostic (6.39e-2)" "unprognostic (1.15e-2)" "unprognostic (1.14e-1)" "unprognostic (3.33e-2)" "unprognostic (2.94e-2)" "unprognostic (1.46e-1)" "unprognostic (9.57e-2)" "unprognostic (2.65e-1)" RACK1 "Gnb2-rs1, GNB2L1, H12.3" ENSG00000204628 "Receptor for activated C kinase 1" P63244 5 181236897-181248096 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins, Transporters" "Apoptosis, Biological rhythms, Cell cycle, Gastrulation, Growth regulation, Host-virus interaction, Translation regulation" "Developmental protein, Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Decidual stromal cells: 5852.9;Esophageal basal cells: 5533.8;Esophageal suprabasal cells: 5492.5;Extravillous trophoblasts: 5478.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004288, HPA021676" Uncertain Supported Nucleoplasm,Cytosol NA NA 470000 "Cluster 18: Non-specific - Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 508 Nucleoplasm Cytosol "CAB004288: , HPA021676: " "unprognostic (3.82e-1)" "unprognostic (7.95e-2)" "unprognostic (2.71e-1)" "unprognostic (3.38e-1)" "unprognostic (1.84e-1)" "unprognostic (1.23e-2)" "unprognostic (3.62e-1)" "unprognostic (6.26e-3)" "unprognostic (3.92e-2)" "potential prognostic favorable (9.70e-5)" "unprognostic (4.18e-2)" "unprognostic (6.52e-2)" "potential prognostic unfavorable (7.47e-9)" "unprognostic (2.04e-2)" "unprognostic (2.72e-2)" "unprognostic (1.50e-1)" "unprognostic (2.38e-1)" "unprognostic (9.46e-2)" "unprognostic (1.03e-3)" "unprognostic (1.36e-1)" "unprognostic (2.37e-1)" "unprognostic (3.72e-1)" "unprognostic (7.23e-2)" "unprognostic (4.66e-2)" "unprognostic (4.04e-1)" "unprognostic (2.36e-1)" "unprognostic (2.41e-1)" "unprognostic (4.25e-1)" "unprognostic (3.69e-1)" RAD1 "HRAD1, REC1" ENSG00000113456 "RAD1 checkpoint DNA exonuclease" O60671 5 34905260-34918989 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 96.9;Migrating cytotrophoblasts: 92.1;Oocytes: 119.7;Syncytiotrophoblasts: 103.2" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 4 "Uterine Corpus Endometrial Carcinoma (TCGA): 52.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006692 Approved Approved Nucleoplasm,Vesicles NA Yes "Cluster 3: Non-specific - Nuclear processes" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 29: Non-specific - Unknown function" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 28 "Nucleoplasm, Vesicles" "HPA006692: " "unprognostic (9.24e-3)" "unprognostic (5.32e-3)" "potential prognostic unfavorable (1.25e-5)" "unprognostic (3.27e-1)" "unprognostic (3.23e-2)" "unprognostic (3.45e-1)" "unprognostic (2.67e-1)" "unprognostic (1.10e-1)" "unprognostic (3.14e-2)" "unprognostic (1.42e-3)" "potential prognostic favorable (5.86e-4)" "unprognostic (3.55e-2)" "unprognostic (9.48e-2)" "potential prognostic unfavorable (1.63e-4)" "unprognostic (1.81e-3)" "unprognostic (3.18e-2)" "unprognostic (6.16e-2)" "unprognostic (3.67e-1)" "unprognostic (6.45e-2)" "unprognostic (2.01e-3)" "unprognostic (4.28e-1)" "unprognostic (4.24e-2)" "unprognostic (1.28e-2)" "unprognostic (4.04e-3)" "unprognostic (8.51e-3)" "unprognostic (3.18e-1)" "unprognostic (2.26e-2)" "unprognostic (4.33e-2)" "unprognostic (1.98e-1)" "unprognostic (1.02e-1)" "unprognostic (1.18e-1)" RAD17 "CCYC, RAD17Sp, Rad24" ENSG00000152942 "RAD17 checkpoint clamp loader component" O75943 5 69369293-69414801 "Essential proteins, Predicted intracellular proteins" "Cell cycle, DNA damage" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 44.7;Early primary spermatocytes: 56.6;Early spermatids: 41.9;Late primary spermatocytes: 52.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004551, HPA005448" Approved Supported Nucleoplasm NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 67: Testis - Mixed function" "Cluster 55: Non-specific - Transcription" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 102: Non-specific - Mixed function" 34 Nucleoplasm "CAB004551: , HPA005448: " "unprognostic (8.01e-2)" "unprognostic (1.27e-1)" "unprognostic (3.05e-1)" "unprognostic (2.36e-1)" "unprognostic (9.36e-3)" "unprognostic (1.28e-1)" "unprognostic (5.03e-2)" "unprognostic (1.40e-1)" "unprognostic (2.81e-2)" "unprognostic (2.15e-1)" "potential prognostic favorable (6.07e-5)" "unprognostic (2.51e-2)" "unprognostic (8.14e-2)" "unprognostic (6.21e-3)" "unprognostic (1.83e-2)" "unprognostic (2.22e-1)" "unprognostic (3.56e-1)" "unprognostic (7.33e-2)" "unprognostic (3.98e-2)" "unprognostic (1.07e-2)" "unprognostic (7.37e-3)" "unprognostic (3.99e-1)" "unprognostic (1.38e-3)" "unprognostic (7.73e-2)" "unprognostic (3.10e-2)" "unprognostic (4.17e-1)" "unprognostic (7.91e-2)" "unprognostic (1.71e-2)" "unprognostic (1.78e-1)" "unprognostic (4.88e-2)" "unprognostic (1.32e-1)" RAD18 RNF73 ENSG00000070950 "RAD18 E3 ubiquitin protein ligase" Q9NS91 3 8775402-8963773 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006716, HPA006724, HPA008752, CAB080160, CAB080162" Supported Approved Supported "Nucleoplasm,Nuclear speckles,Nuclear bodies" NA Yes "Cluster 5: Non-specific - Cell proliferation" "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 34: Non-specific - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 35: Neurons - Synaptic function & neurogenesis" 67 "Nucleoplasm, Nuclear bodies" "Nuclear speckles" "CAB080160: , CAB080162: , HPA006716: , HPA006724: , HPA008752: " "unprognostic (3.07e-1)" "unprognostic (1.34e-2)" "unprognostic (2.51e-1)" "unprognostic (7.57e-3)" "unprognostic (1.23e-1)" "unprognostic (8.36e-2)" "unprognostic (3.24e-2)" "unprognostic (2.85e-1)" "unprognostic (9.33e-2)" "potential prognostic unfavorable (3.24e-4)" "unprognostic (3.39e-2)" "unprognostic (6.52e-2)" "unprognostic (3.77e-1)" "potential prognostic unfavorable (1.21e-4)" "unprognostic (1.38e-3)" "unprognostic (4.79e-3)" "unprognostic (2.00e-2)" "unprognostic (8.02e-2)" "unprognostic (1.33e-2)" "unprognostic (1.34e-1)" "unprognostic (6.13e-3)" "unprognostic (3.84e-2)" "unprognostic (8.46e-3)" "potential prognostic unfavorable (7.99e-4)" "unprognostic (1.51e-3)" "unprognostic (1.35e-3)" "unprognostic (1.78e-1)" "unprognostic (5.72e-2)" "unprognostic (3.34e-1)" "unprognostic (1.87e-2)" "unprognostic (9.18e-2)" RAD21 "hHR21, KIAA0078, SCC1" ENSG00000164754 "RAD21 cohesin complex component" O60216 8 116845934-116874776 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Chromosome partition, DNA damage, DNA repair, Mitosis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 737.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020044, CAB022065, HPA073277" Supported Enhanced Nucleoplasm NA Yes "Cluster 3: Non-specific - Nuclear processes" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 79 Nucleoplasm "CAB022065: , HPA020044: , HPA073277: " "unprognostic (5.78e-2)" "unprognostic (5.76e-2)" "unprognostic (2.16e-1)" "unprognostic (1.24e-3)" "unprognostic (1.14e-1)" "unprognostic (8.08e-3)" "unprognostic (6.80e-2)" "unprognostic (6.18e-2)" "unprognostic (1.25e-1)" "potential prognostic unfavorable (3.58e-5)" "potential prognostic favorable (2.87e-5)" "unprognostic (3.26e-2)" "unprognostic (1.07e-1)" "unprognostic (8.11e-3)" "potential prognostic unfavorable (6.22e-4)" "potential prognostic unfavorable (9.23e-4)" "unprognostic (1.83e-3)" "unprognostic (2.85e-2)" "unprognostic (9.44e-2)" "unprognostic (1.63e-1)" "unprognostic (1.93e-1)" "unprognostic (1.69e-2)" "unprognostic (5.27e-3)" "unprognostic (2.66e-2)" "unprognostic (1.82e-1)" "unprognostic (1.56e-1)" "unprognostic (6.60e-2)" "unprognostic (3.05e-1)" "unprognostic (1.97e-1)" "unprognostic (2.17e-2)" "unprognostic (1.68e-1)" RAD21L1 "dJ545L17.2, RAD21L" ENSG00000244588 "RAD21 cohesin complex component like 1" Q9H4I0 20 1226044-1296421 "Predicted intracellular proteins" "Chromosome partition, Meiosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 12 "testis: 10.0" "Group enriched" "Detected in some" 14 "Early primary spermatocytes: 103.6;Early spermatids: 183.9;Late primary spermatocytes: 58.9;Late spermatids: 201.8" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Bladder cancer: 1.2" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" HPA053282 Approved NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 3: Early primary spermatocytes - Early meiosis" "HPA053282: " RAD23A "HHR23A, MGC111083" ENSG00000179262 "RAD23 homolog A, nucleotide excision repair protein" P54725 19 12945855-12953642 "Cancer-related genes, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "skeletal muscle: 921.7;tongue: 418.3" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026418, HPA053901, HPA057003, HPA065599" Approved Supported "Nucleoplasm,Golgi apparatus,Vesicles,Cytosol" NA NA 2600000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 14: Neurons - Synaptic function" "Cluster 23: Non-specific - Transcription" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 94 Nucleoplasm "Golgi apparatus, Vesicles, Cytosol" "HPA026418: , HPA053901: , HPA057003: , HPA065599: " "unprognostic (3.11e-1)" "unprognostic (1.09e-1)" "unprognostic (4.20e-2)" "potential prognostic favorable (4.96e-4)" "unprognostic (5.20e-2)" "unprognostic (3.11e-2)" "unprognostic (2.13e-1)" "unprognostic (7.28e-2)" "unprognostic (5.59e-2)" "unprognostic (2.25e-1)" "unprognostic (2.00e-1)" "unprognostic (2.33e-2)" "unprognostic (4.92e-3)" "validated prognostic unfavorable (2.58e-4)" "validated prognostic unfavorable (3.41e-4)" "potential prognostic unfavorable (5.70e-5)" "unprognostic (1.81e-2)" "unprognostic (2.88e-2)" "unprognostic (1.15e-1)" "unprognostic (8.24e-2)" "unprognostic (6.10e-2)" "unprognostic (1.39e-2)" "unprognostic (3.76e-1)" "unprognostic (2.45e-1)" "unprognostic (1.84e-1)" "unprognostic (7.04e-2)" "unprognostic (1.22e-2)" "unprognostic (2.55e-2)" "unprognostic (2.80e-1)" "unprognostic (2.71e-1)" "unprognostic (1.08e-2)" RAD23B "HHR23B, HR23B, P58" ENSG00000119318 "RAD23 homolog B, nucleotide excision repair protein" P54727 9 107283137-107332192 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 2069.5;Neutrophils: 668.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029718, HPA029720, CAB033868" Enhanced Supported Nucleoplasm,Cytosol No No 4800000 "Cluster 24: Non-specific - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 16: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 72 Nucleoplasm Cytosol "CAB033868: , HPA029718: , HPA029720: " "unprognostic (1.22e-1)" "unprognostic (1.41e-3)" "unprognostic (1.87e-1)" "unprognostic (7.12e-2)" "unprognostic (5.22e-2)" "unprognostic (1.01e-2)" "unprognostic (1.82e-2)" "unprognostic (1.41e-1)" "unprognostic (1.98e-2)" "unprognostic (1.28e-2)" "potential prognostic favorable (1.32e-6)" "unprognostic (1.08e-2)" "unprognostic (1.97e-2)" "unprognostic (2.74e-1)" "unprognostic (4.69e-3)" "potential prognostic unfavorable (1.58e-4)" "unprognostic (1.64e-3)" "unprognostic (5.89e-2)" "unprognostic (1.06e-1)" "unprognostic (2.67e-2)" "unprognostic (8.11e-3)" "unprognostic (7.83e-3)" "unprognostic (4.10e-1)" "unprognostic (3.96e-2)" "unprognostic (2.13e-1)" "unprognostic (2.87e-1)" "unprognostic (1.60e-1)" "unprognostic (1.57e-1)" "unprognostic (2.88e-1)" "unprognostic (4.53e-2)" "unprognostic (1.44e-2)" RAD50 "hRad50, RAD50-2" ENSG00000113522 "RAD50 double strand break repair protein" Q92878 5 132556019-132646349 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair, Host-virus interaction, Meiosis" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 8 "Astrocytes: 88.7;Bergmann glia: 99.0;Brain excitatory neurons: 87.2;Brain inhibitory neurons: 105.7;Choroid plexus epithelial cells: 91.5;Ependymal cells: 95.5;Microglia: 76.8;Oligodendrocyte progenitor cells: 101.0;Oligodendrocytes: 124.0;Other brain neurons: 79.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022103, CAB024979, HPA052291, CAB080379" Supported Supported "Nucleoplasm,Nuclear bodies" NA NA 6300 "Cluster 5: Non-specific - Cell proliferation" "Cluster 74: Non-specific - Signal transduction" "Cluster 9: Non-specific - Receptor signaling" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 22: Non-specific - Basic cellular functions" 69 Nucleoplasm "Nuclear bodies" "CAB022103: , CAB024979: , CAB080379: , HPA052291: " "unprognostic (1.57e-2)" "unprognostic (5.02e-3)" "unprognostic (2.57e-1)" "unprognostic (8.67e-2)" "unprognostic (1.68e-1)" "unprognostic (3.53e-1)" "unprognostic (1.05e-1)" "unprognostic (1.84e-1)" "potential prognostic unfavorable (5.13e-5)" "unprognostic (1.19e-2)" "potential prognostic favorable (6.56e-6)" "unprognostic (5.70e-3)" "unprognostic (1.43e-2)" "unprognostic (1.84e-2)" "unprognostic (2.58e-1)" "unprognostic (3.09e-3)" "unprognostic (1.48e-1)" "unprognostic (2.80e-2)" "unprognostic (3.70e-1)" "unprognostic (1.69e-1)" "unprognostic (5.73e-3)" "unprognostic (3.11e-2)" "unprognostic (3.82e-2)" "unprognostic (3.03e-2)" "unprognostic (3.57e-2)" "unprognostic (7.42e-2)" "unprognostic (3.45e-1)" "unprognostic (8.88e-2)" "unprognostic (1.64e-1)" "unprognostic (1.16e-1)" "unprognostic (2.29e-2)" RAD51 "BRCC5, FANCR, HsRad51, HsT16930, RAD51A, RECA" ENSG00000051180 "RAD51 recombinase" Q06609 15 40694774-40732340 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 14.6;testis: 22.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 43.3;Differentiating spermatogonia: 31.0;Early primary spermatocytes: 54.4;Epicardial cells: 52.3;Erythrocyte progenitors: 40.7;Extravillous trophoblasts: 89.0;Late primary spermatocytes: 57.4;Megakaryocyte progenitors: 31.5;Migrating cytotrophoblasts: 61.4;Monocyte progenitors: 37.0;Oocytes: 82.9" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 47.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB010381, HPA039310" Enhanced Supported Nucleoli,Mitochondria,Cytosol NA Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 48: Non-specific - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 27: Non-specific - Cell proliferation" 107 Nucleoli "Mitochondria, Cytosol" "CAB010381: , HPA039310: " "potential prognostic unfavorable (6.19e-4)" "unprognostic (5.10e-3)" "unprognostic (7.71e-2)" "unprognostic (2.47e-1)" "unprognostic (3.05e-1)" "unprognostic (1.97e-1)" "unprognostic (5.24e-2)" "unprognostic (6.75e-3)" "unprognostic (1.71e-1)" "potential prognostic unfavorable (1.27e-5)" "validated prognostic unfavorable (8.79e-6)" "validated prognostic unfavorable (6.47e-5)" "potential prognostic unfavorable (6.51e-8)" "validated prognostic unfavorable (1.92e-4)" "validated prognostic unfavorable (5.09e-8)" "validated prognostic unfavorable (5.03e-5)" "validated prognostic unfavorable (5.33e-5)" "unprognostic (5.84e-2)" "unprognostic (2.04e-2)" "unprognostic (1.22e-1)" "unprognostic (1.40e-1)" "validated prognostic unfavorable (4.22e-4)" "validated prognostic unfavorable (2.27e-5)" "unprognostic (6.13e-2)" "unprognostic (6.13e-2)" "unprognostic (2.58e-1)" "unprognostic (7.22e-2)" "unprognostic (3.00e-2)" "unprognostic (2.79e-1)" "unprognostic (1.34e-1)" "unprognostic (1.56e-1)" RAD51AP1 PIR51 ENSG00000111247 "RAD51 associated protein 1" Q96B01 12 4538798-4560047 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Meiosis" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 15.9;lymphoid tissue: 13.4" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 41.4;Early primary spermatocytes: 56.0;Early spermatids: 58.5;Enteric transient amplifying cells: 41.9;Erythrocyte progenitors: 78.8;Extravillous trophoblasts: 41.3;Hofbauer cells: 65.0;Late spermatids: 121.3;Megakaryocyte progenitors: 50.8;Migrating cytotrophoblasts: 36.4;Monocyte progenitors: 65.3;Neutrophil progenitors: 36.5;Oocytes: 69.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 7.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051499 Approved Nucleoplasm Yes Yes "Cluster 13: Non-specific - Mitochondria" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 38: Non-specific - Transcription" "Cluster 27: Non-specific - Cell proliferation" 10 Nucleoplasm "HPA051499: " "unprognostic (1.80e-1)" "unprognostic (1.30e-1)" "unprognostic (5.41e-2)" "unprognostic (8.25e-2)" "unprognostic (1.82e-1)" "unprognostic (2.00e-1)" "unprognostic (9.71e-2)" "unprognostic (1.50e-3)" "unprognostic (2.35e-2)" "unprognostic (4.84e-2)" "unprognostic (6.41e-3)" "potential prognostic unfavorable (4.98e-5)" "potential prognostic unfavorable (3.31e-8)" "validated prognostic unfavorable (3.36e-4)" "validated prognostic unfavorable (1.94e-4)" "unprognostic (1.15e-3)" "unprognostic (1.95e-3)" "unprognostic (1.75e-3)" "unprognostic (1.69e-1)" "unprognostic (1.46e-2)" "unprognostic (3.37e-1)" "validated prognostic unfavorable (9.46e-5)" "validated prognostic unfavorable (1.26e-5)" "unprognostic (7.85e-2)" "unprognostic (1.46e-2)" "unprognostic (9.93e-3)" "unprognostic (1.39e-2)" "unprognostic (5.18e-2)" "unprognostic (1.83e-1)" "unprognostic (7.54e-2)" "unprognostic (2.89e-1)" RAD51AP2 FLJ17540 ENSG00000214842 "RAD51 associated protein 2" Q09MP3 2 17510579-17518440 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 29 "testis: 8.8" "Cell type enriched" "Detected in some" 38 "Early primary spermatocytes: 511.0" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA079469 Approved "Nucleoli,Mitotic chromosome,Cytosol" Yes NA "Cluster 57: Testis - Spermatogenesis" "Cluster 53: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 3: Early primary spermatocytes - Early meiosis" 1 Nucleoli "Mitotic chromosome, Cytosol" "HPA079469: " RAD51B "hREC2, R51H2, RAD51L1, REC2" ENSG00000182185 "RAD51 paralog B" O15315 14 67819779-68730218 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pituitary stem cells: 1279.5;Renal connecting tubule cells: 936.1" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 800.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB016191, HPA051869" Enhanced Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 32: Basophils - Transcription" "Cluster 55: Breast - Lactation" "Cluster 11: White matter - Signal transduction" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 94: Gonadal somatic cells - Mixed function" 17 "Nuclear bodies" Nucleoplasm "CAB016191: , HPA051869: " "potential prognostic unfavorable (8.07e-4)" "unprognostic (6.23e-2)" "unprognostic (1.19e-1)" "unprognostic (7.10e-2)" "unprognostic (3.37e-2)" "unprognostic (1.94e-1)" "unprognostic (7.40e-2)" "unprognostic (3.11e-3)" "unprognostic (5.22e-2)" "potential prognostic favorable (7.92e-4)" "unprognostic (1.76e-2)" "unprognostic (1.33e-1)" "unprognostic (1.70e-2)" "unprognostic (7.30e-3)" "unprognostic (1.95e-1)" "unprognostic (8.08e-2)" "unprognostic (5.16e-2)" "unprognostic (1.92e-1)" "unprognostic (2.90e-1)" "unprognostic (3.34e-1)" "unprognostic (1.28e-2)" "unprognostic (1.46e-3)" "unprognostic (2.98e-1)" "unprognostic (1.44e-2)" "unprognostic (1.72e-1)" "unprognostic (2.36e-1)" "unprognostic (3.73e-2)" "unprognostic (5.05e-2)" "unprognostic (1.07e-1)" "unprognostic (1.85e-1)" RAD51C "FANCO, RAD51L2" ENSG00000108384 "RAD51 paralog C" O43502 17 58692573-58735611 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" DNA-binding "Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early primary spermatocytes: 164.8;Extravillous trophoblasts: 128.9;Late primary spermatocytes: 149.5;Oocytes: 216.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA045198 Supported "Nucleoplasm,Vesicles,Cell Junctions,Mitochondria,Cytosol" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 48: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 33 "Nucleoplasm, Mitochondria, Cytosol" "Vesicles, Cell Junctions" "HPA045198: " "unprognostic (3.72e-1)" "unprognostic (3.02e-3)" "unprognostic (3.01e-2)" "unprognostic (4.17e-3)" "unprognostic (1.34e-1)" "unprognostic (9.50e-2)" "unprognostic (4.12e-1)" "unprognostic (3.66e-2)" "unprognostic (1.31e-1)" "potential prognostic unfavorable (8.40e-4)" "unprognostic (6.49e-3)" "unprognostic (2.66e-1)" "unprognostic (9.19e-2)" "validated prognostic unfavorable (2.22e-5)" "validated prognostic unfavorable (1.02e-7)" "unprognostic (3.54e-2)" "unprognostic (1.79e-1)" "unprognostic (9.82e-3)" "unprognostic (3.04e-3)" "unprognostic (7.89e-3)" "unprognostic (1.20e-1)" "unprognostic (7.23e-3)" "unprognostic (9.75e-2)" "unprognostic (7.81e-2)" "unprognostic (1.29e-1)" "potential prognostic favorable (1.16e-4)" "unprognostic (6.09e-3)" "unprognostic (6.65e-2)" "unprognostic (6.47e-2)" "unprognostic (7.20e-2)" "unprognostic (8.48e-2)" RAD51D "HsTRAD, R51H3, RAD51L3, Trad" ENSG00000185379 "RAD51 paralog D" O75771 17 35092221-35121522 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 17 "Early spermatids: 51.6;Late spermatids: 168.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 74: Non-specific - Signal transduction" "Cluster 34: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 48 "unprognostic (1.37e-1)" "unprognostic (1.32e-3)" "unprognostic (1.27e-1)" "unprognostic (1.43e-1)" "unprognostic (3.50e-2)" "unprognostic (4.86e-2)" "unprognostic (2.56e-1)" "unprognostic (4.93e-1)" "potential prognostic unfavorable (7.89e-4)" "unprognostic (1.21e-2)" "unprognostic (3.09e-3)" "unprognostic (1.19e-1)" "potential prognostic unfavorable (1.87e-4)" "unprognostic (5.78e-3)" "unprognostic (1.08e-1)" "unprognostic (5.04e-3)" "unprognostic (4.85e-2)" "unprognostic (4.72e-2)" "unprognostic (1.78e-3)" "unprognostic (1.45e-1)" "potential prognostic favorable (8.10e-4)" "unprognostic (1.26e-1)" "unprognostic (3.10e-1)" "unprognostic (8.48e-3)" "potential prognostic favorable (8.41e-4)" "unprognostic (3.08e-2)" "unprognostic (9.45e-2)" "unprognostic (5.44e-1)" "unprognostic (1.02e-2)" "unprognostic (1.92e-1)" RAD52 ENSG00000002016 "RAD52 homolog, DNA repair protein" P43351 12 911736-990053 "Cancer-related genes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 113.9;Epicardial cells: 127.4;Myonuclei: 144.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028957 Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 38: Non-specific - Transcription" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 24 "Nuclear speckles" "Plasma membrane" "HPA028957: " "unprognostic (1.69e-1)" "unprognostic (6.64e-2)" "unprognostic (3.60e-1)" "unprognostic (4.28e-3)" "unprognostic (1.82e-1)" "unprognostic (1.90e-1)" "unprognostic (1.17e-1)" "unprognostic (9.70e-3)" "unprognostic (7.64e-2)" "potential prognostic unfavorable (1.65e-5)" "unprognostic (2.98e-3)" "unprognostic (6.54e-2)" "unprognostic (2.60e-1)" "unprognostic (3.09e-3)" "unprognostic (1.44e-1)" "unprognostic (2.29e-1)" "unprognostic (1.05e-1)" "unprognostic (1.25e-2)" "unprognostic (2.04e-1)" "unprognostic (6.36e-2)" "unprognostic (8.19e-2)" "unprognostic (4.29e-3)" "unprognostic (8.84e-3)" "unprognostic (4.05e-1)" "potential prognostic favorable (7.14e-4)" "unprognostic (1.27e-1)" "unprognostic (1.51e-1)" "unprognostic (8.70e-2)" "unprognostic (4.71e-1)" "unprognostic (8.87e-2)" "unprognostic (1.22e-1)" RAD54B RDH54 ENSG00000197275 "RAD54 homolog B" Q9Y620 8 94371960-94475115 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 18.0;Early primary spermatocytes: 22.2;Erythrocyte progenitors: 29.1;Fallopian tube ciliated cells: 34.9;Megakaryocyte progenitors: 23.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 10 "B-cells: 1.0;T-cells: 1.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA007087 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 5: Non-specific - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 11 "Nucleoplasm, Cytosol" "HPA007087: " "unprognostic (2.49e-2)" "unprognostic (1.91e-2)" "unprognostic (3.85e-1)" "unprognostic (2.85e-2)" "unprognostic (1.79e-1)" "unprognostic (2.59e-1)" "unprognostic (3.36e-2)" "unprognostic (3.80e-1)" "unprognostic (1.59e-1)" "validated prognostic unfavorable (8.00e-6)" "validated prognostic unfavorable (8.76e-4)" "potential prognostic unfavorable (5.03e-4)" "potential prognostic unfavorable (2.75e-6)" "unprognostic (1.39e-2)" "potential prognostic unfavorable (3.11e-4)" "unprognostic (2.83e-3)" "unprognostic (1.35e-1)" "unprognostic (4.44e-2)" "unprognostic (1.10e-1)" "unprognostic (2.66e-1)" "unprognostic (8.89e-3)" "potential prognostic unfavorable (7.11e-4)" "unprognostic (7.07e-2)" "unprognostic (3.55e-2)" "unprognostic (1.93e-1)" "unprognostic (1.60e-2)" "unprognostic (9.08e-2)" "unprognostic (1.86e-1)" "unprognostic (5.14e-3)" RAD54L "hHR54, hRAD54, RAD54A" ENSG00000085999 "RAD54 like" Q92698 1 46246461-46278480 "Enzymes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 8.2;lymphoid tissue: 14.3;testis: 11.8" "Group enriched" "Detected in many" 4 "Endometrial glandular cells: 189.9;Endometrial luminal cells: 488.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.1" "Lineage enhanced" "Detected in single" "T-cells: 1.1" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA028954, HPA051537" Uncertain Enhanced Nucleoplasm NA Yes "Cluster 9: T-regs - Cell cycle regulation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 37: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 5 Nucleoplasm "HPA028954: , HPA051537: " "unprognostic (1.67e-1)" "unprognostic (3.29e-2)" "unprognostic (4.54e-1)" "unprognostic (1.83e-1)" "unprognostic (3.82e-2)" "unprognostic (1.16e-2)" "unprognostic (2.44e-1)" "unprognostic (1.75e-2)" "unprognostic (2.33e-2)" "validated prognostic unfavorable (1.13e-5)" "validated prognostic unfavorable (1.94e-5)" "unprognostic (1.09e-3)" "validated prognostic unfavorable (1.99e-5)" "validated prognostic unfavorable (3.14e-6)" "validated prognostic unfavorable (7.02e-4)" "validated prognostic unfavorable (2.43e-4)" "unprognostic (3.00e-2)" "unprognostic (5.44e-2)" "unprognostic (1.25e-1)" "unprognostic (1.13e-3)" "unprognostic (1.32e-3)" "unprognostic (1.11e-3)" "unprognostic (5.62e-2)" "unprognostic (1.54e-2)" "unprognostic (1.20e-3)" "potential prognostic unfavorable (2.37e-4)" "unprognostic (2.06e-2)" "unprognostic (1.81e-1)" "unprognostic (7.98e-3)" RAD54L2 "ARIP4, KIAA0809, SRISNF2L" ENSG00000164080 "RAD54 like 2" Q9Y4B4 3 51538719-51668667 "Enzymes, Predicted intracellular proteins" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035004, HPA039992, HPA077351" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 24: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Transcription" 33 Nucleoplasm Cytosol "HPA035004: , HPA039992: , HPA077351: " "unprognostic (7.31e-2)" "unprognostic (2.43e-1)" "unprognostic (6.38e-2)" "unprognostic (2.52e-1)" "unprognostic (1.27e-1)" "unprognostic (2.51e-3)" "unprognostic (6.70e-2)" "unprognostic (3.02e-2)" "unprognostic (1.51e-2)" "unprognostic (1.80e-2)" "potential prognostic favorable (2.82e-4)" "unprognostic (8.13e-3)" "unprognostic (3.11e-2)" "unprognostic (1.37e-1)" "unprognostic (1.00e-1)" "unprognostic (5.43e-2)" "unprognostic (1.68e-1)" "unprognostic (9.75e-2)" "unprognostic (2.37e-3)" "unprognostic (1.32e-1)" "potential prognostic unfavorable (1.94e-4)" "unprognostic (2.84e-1)" "unprognostic (1.89e-1)" "unprognostic (1.17e-1)" "unprognostic (4.86e-2)" "potential prognostic favorable (3.93e-4)" "unprognostic (9.82e-2)" "unprognostic (1.38e-1)" "unprognostic (1.93e-1)" "unprognostic (1.62e-2)" "unprognostic (3.49e-1)" RAD9A RAD9 ENSG00000172613 "RAD9 checkpoint clamp component A" Q99638 11 67317871-67398410 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" "DNA damage" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 274.3;Choroid plexus epithelial cells: 277.5;Epicardial cells: 459.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006725, HPA048155, CAB079979" Enhanced Enhanced "Nucleoplasm,Nuclear bodies" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 49: Non-specific - Transcription" "Cluster 17: Choroid plexus - Cilium" "Cluster 24: Non-specific - Unknown function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 43 Nucleoplasm "Nuclear bodies" "CAB079979: , HPA006725: , HPA048155: " "unprognostic (2.83e-2)" "unprognostic (7.86e-2)" "unprognostic (1.77e-1)" "unprognostic (1.98e-1)" "unprognostic (9.49e-3)" "unprognostic (9.54e-2)" "unprognostic (2.85e-1)" "unprognostic (9.15e-3)" "potential prognostic favorable (7.89e-4)" "unprognostic (6.47e-2)" "unprognostic (3.20e-2)" "unprognostic (5.36e-2)" "unprognostic (1.12e-1)" "unprognostic (1.05e-3)" "unprognostic (2.36e-2)" "unprognostic (4.53e-2)" "unprognostic (7.31e-3)" "unprognostic (1.73e-1)" "unprognostic (2.41e-1)" "unprognostic (1.29e-1)" "potential prognostic favorable (4.41e-4)" "unprognostic (1.42e-1)" "unprognostic (1.94e-3)" "unprognostic (1.06e-2)" "unprognostic (4.12e-3)" "potential prognostic favorable (6.77e-4)" "unprognostic (1.38e-1)" "unprognostic (7.48e-2)" "unprognostic (3.26e-1)" "unprognostic (2.94e-1)" "unprognostic (1.32e-1)" RAD9B FLJ40346 ENSG00000151164 "RAD9 checkpoint clamp component B" Q6WBX8 12 110501655-110533556 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 12 "testis: 10.7" "Cell type enriched" "Detected in many" 4 "Early primary spermatocytes: 189.9" "Cell type enhanced" "Detected in many" "ependymal cell: 6.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 5 "basophil: 4.7" "Lineage enriched" "Detected in single" 5 "granulocytes: 4.7" "Not detected" "Not detected" "Prostate - Smooth muscle cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040643 Approved NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 67: Testis - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 3: Early primary spermatocytes - Early meiosis" "HPA040643: " "unprognostic (1.88e-1)" "potential prognostic favorable (6.73e-4)" "unprognostic (1.25e-3)" "unprognostic (1.06e-1)" "unprognostic (6.98e-2)" RADIL "FLJ10324, KIAA1849, RASIP2" ENSG00000157927 "Rap associating with DIL domain" Q96JH8 7 4797055-4883716 "Predicted intracellular proteins" "Cell adhesion" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 8.4" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 42.5;Breast lactating cells: 80.1;Differentiating spermatogonia: 42.6;Ependymal cells: 53.5;Fibro-adipogenic progenitors: 54.1;Late primary spermatocytes: 45.6;Lymphatic endothelial cells: 63.8;Retinal amacrine cells: 69.4;Thyrotrophs: 34.7" "Cell type enhanced" "Detected in all" "fibroblast: 90.4;pericyte: 70.8" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 3.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 13.9" "Adipose subcutaneous - Smooth muscle cells, Kidney - Fibroblasts, Prostate - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051776 Approved Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 67: Testis - Mixed function" "Cluster 25: Non-specific - Transcription" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 108: Fibroblasts - ECM organization" 13 "Nucleoplasm, Nuclear membrane" "HPA051776: " "unprognostic (1.02e-1)" "unprognostic (5.13e-2)" "unprognostic (7.15e-3)" "unprognostic (1.89e-1)" RADX "CXorf57, FLJ10178, FLJ14191" ENSG00000147231 "RPA1 related single stranded DNA binding protein, X-linked" Q6NSI4 X 106611930-106679439 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.2;pituitary gland: 19.2" "Cell type enhanced" "Detected in many" "Corticotrophs: 59.9;Gonadotrophs: 67.1;Lactotrophs: 100.2;Neuroendocrine cells: 51.7;Other brain neurons: 52.1;Pancreatic islet cells: 44.8;Somatotrophs: 82.2;Thyrotrophs: 57.7" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 8.1" "Region enriched" "Detected in many" 5 "hypothalamus: 54.2" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 11 "B-cells: 1.8;NK-cells: 1.0;T-cells: 1.5" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2, Pancreas - Alpha cells, Skeletal muscle - Fibroblasts, Stomach - Gastric mucous cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA000896, HPA001010, HPA001374" Uncertain Supported "Nuclear speckles" NA No "Cluster 24: Non-specific - Transcription" "Cluster 36: Brain & Liver - Signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 1: Neuronal - Visual perception" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 15 "Nuclear speckles" "HPA000896: , HPA001010: , HPA001374: " "unprognostic (1.22e-3)" "unprognostic (8.15e-3)" "unprognostic (1.10e-1)" "unprognostic (2.13e-2)" "unprognostic (4.40e-2)" "potential prognostic favorable (1.49e-4)" "unprognostic (8.95e-3)" "potential prognostic unfavorable (2.11e-5)" "unprognostic (1.11e-2)" "unprognostic (8.14e-2)" "unprognostic (3.09e-1)" "unprognostic (2.31e-1)" "unprognostic (5.86e-3)" "unprognostic (7.17e-3)" "unprognostic (2.52e-1)" "unprognostic (1.88e-1)" "unprognostic (1.80e-2)" RAE1 "Gle2, Mnrp41" ENSG00000101146 "Ribonucleic acid export 1" P78406 20 57351223-57379211 "Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Host-virus interaction, Mitosis, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 96.1" "Cell type enhanced" "Detected in many" "Early spermatids: 117.6;Late primary spermatocytes: 384.8;Oocytes: 386.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048795 Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 62: Non-specific - Plasma proteins" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 55 "Nucleoplasm, Nucleoli fibrillar center" "HPA048795: " "unprognostic (9.80e-2)" "unprognostic (9.12e-2)" "unprognostic (6.51e-2)" "unprognostic (9.48e-2)" "unprognostic (1.62e-1)" "unprognostic (1.60e-2)" "unprognostic (1.91e-1)" "unprognostic (5.35e-2)" "unprognostic (6.22e-2)" "unprognostic (1.50e-2)" "unprognostic (1.75e-2)" "unprognostic (8.71e-2)" "unprognostic (7.24e-2)" "validated prognostic unfavorable (6.13e-7)" "validated prognostic unfavorable (1.42e-4)" "unprognostic (6.01e-2)" "unprognostic (4.81e-2)" "unprognostic (3.65e-3)" "potential prognostic favorable (7.12e-4)" "unprognostic (2.64e-1)" "unprognostic (1.17e-1)" "unprognostic (3.27e-2)" "unprognostic (8.27e-3)" "potential prognostic unfavorable (7.51e-4)" "unprognostic (4.41e-2)" "unprognostic (4.33e-3)" "unprognostic (2.98e-1)" "unprognostic (2.68e-1)" "unprognostic (1.54e-1)" "unprognostic (4.44e-2)" "unprognostic (3.28e-1)" RAET1E "bA350J20.7, LETAL, ULBP4" ENSG00000164520 "Retinoic acid early transcript 1E" Q8TD07 6 149883179-149898113 "Predicted intracellular proteins, Predicted membrane proteins" Immunity "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 14.5;esophagus: 37.6;vagina: 18.1" "Cell type enhanced" "Detected in some" "Esophageal apical cells: 13.1;Esophageal suprabasal cells: 7.7;Ocular epithelial cells: 8.0;Papillary tip epithelial cells: 3.8;Podocytes: 37.9;Suprabasal keratinocytes: 21.9" "Cell type enhanced" "Detected in some" "endothelial cell: 4.2" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 11.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "cervical cancer: 23.1" "Adipose visceral - Mesothelial cells, Kidney - Podocytes, Skin - Keratinocyte (other), Spleen - Endothelial cells, Testis - Late spermatids" HPA054022 Supported "Focal adhesion sites,Cytosol" "Intracellular and membrane" Immunity NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 1 "Focal adhesion sites" Cytosol "HPA054022: " "unprognostic (4.33e-2)" "unprognostic (1.11e-3)" "unprognostic (2.74e-1)" "unprognostic (1.01e-1)" "unprognostic (7.99e-3)" "unprognostic (1.24e-2)" "potential prognostic unfavorable (4.48e-4)" "unprognostic (6.35e-2)" "unprognostic (1.90e-2)" "unprognostic (7.00e-3)" "unprognostic (1.29e-2)" "unprognostic (4.63e-2)" "unprognostic (1.72e-1)" "unprognostic (1.06e-1)" RAET1G ULBP5 ENSG00000203722 "Retinoic acid early transcript 1G" Q6H3X3 6 149916878-149923121 "Predicted membrane proteins, Predicted secreted proteins" "Host-virus interaction, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 7.5;esophagus: 13.8" "Cell type enhanced" "Detected in some" "Esophageal apical cells: 74.4;Esophageal basal cells: 15.0;Esophageal suprabasal cells: 78.0;Mesothelial cells: 16.7;Ocular epithelial cells: 28.9;Suprabasal keratinocytes: 21.7" "Cell type enhanced" "Detected in single" "endothelial cell: 1.4" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 7.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 23.7" "Adipose visceral - Mesothelial cells, Breast - T-cells" "HPA062673, HPA066741" Supported "Vesicles,Plasma membrane" "Secreted - unknown location" Immunity NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 1 "Vesicles, Plasma membrane" "HPA062673: , HPA066741: " "unprognostic (1.90e-2)" "unprognostic (8.20e-2)" "unprognostic (1.45e-1)" "unprognostic (1.04e-1)" "unprognostic (5.57e-2)" "unprognostic (3.56e-1)" "unprognostic (1.80e-1)" "unprognostic (6.54e-3)" "unprognostic (1.69e-1)" "unprognostic (3.28e-1)" RAET1L ENSG00000155918 "Retinoic acid early transcript 1L" Q5VY80 6 150018334-150025532 "Predicted membrane proteins" "Host-virus interaction, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "cervix: 11.9;esophagus: 45.6;vagina: 13.4" "Cell type enriched" "Detected in some" 6 "Esophageal apical cells: 594.2" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 8.1;Head and Neck Squamous Cell Carcinoma (TCGA): 19.4;Lung Squamous Cell Carcinoma (TCGA): 15.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 14.0;Gallbladder cancer: 20.6" "Pancreas - Ductal cells" HPA066741 Supported "Vesicles,Plasma membrane" NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 84: Apical squamous epithelium - Cornification" 2 "Vesicles, Plasma membrane" "HPA066741: " "unprognostic (3.65e-3)" "unprognostic (1.31e-1)" "unprognostic (2.04e-1)" "unprognostic (1.11e-1)" "unprognostic (3.04e-1)" "unprognostic (9.96e-2)" "unprognostic (4.66e-2)" "unprognostic (5.99e-2)" "unprognostic (7.33e-2)" "unprognostic (8.73e-3)" "unprognostic (2.05e-2)" "unprognostic (2.92e-1)" "unprognostic (1.10e-1)" "unprognostic (3.20e-1)" "unprognostic (1.41e-1)" "unprognostic (6.23e-2)" RAF1 "c-Raf, CRAF, Raf-1" ENSG00000132155 "Raf-1 proto-oncogene, serine/threonine kinase" P04049 3 12582101-12664201 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Cardiomyopathy, Deafness, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 163.1" "Cell type enhanced" "Detected in all" "Neutrophils: 859.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 150.3" "Lineage enriched" "Detected in all" 5 "granulocytes: 150.3" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002639, HPA002640, CAB019291, CAB080384" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 24: Neutrophils - Innate immunity signal integration" 284 "Plasma membrane, Cytosol" "CAB019291: , CAB080384: , HPA002639: , HPA002640: " "unprognostic (9.22e-2)" "unprognostic (2.30e-2)" "unprognostic (3.02e-1)" "unprognostic (3.44e-1)" "unprognostic (3.49e-1)" "unprognostic (1.52e-1)" "unprognostic (3.23e-1)" "potential prognostic favorable (3.08e-5)" "unprognostic (1.08e-2)" "potential prognostic unfavorable (4.06e-4)" "potential prognostic favorable (2.76e-5)" "unprognostic (8.03e-2)" "unprognostic (1.57e-2)" "unprognostic (5.91e-3)" "unprognostic (5.31e-2)" "unprognostic (1.15e-1)" "unprognostic (9.58e-2)" "unprognostic (2.15e-1)" "unprognostic (1.22e-1)" "unprognostic (4.47e-2)" "unprognostic (2.75e-2)" "unprognostic (5.12e-3)" "unprognostic (8.51e-3)" "unprognostic (1.22e-1)" "unprognostic (1.24e-1)" "unprognostic (3.08e-2)" "unprognostic (1.97e-1)" "unprognostic (1.62e-1)" "unprognostic (2.75e-1)" "unprognostic (2.03e-1)" "unprognostic (1.24e-1)" RAG1 "MGC43321, RNF74" ENSG00000166349 "Recombination activating 1" P15918 11 36510372-36593156 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA recombination, Ubl conjugation pathway" "Chromatin regulator, DNA-binding, Endonuclease, Hydrolase, Multifunctional enzyme, Nuclease, Transferase" "Disease variant, SCID" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 90 "lymphoid tissue: 367.6" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 7.6;Loop of henle epithelial cells: 8.2;Salivary ionocytes: 38.0;Sertoli cells: 11.2" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 6.8;endothelial cell: 6.8" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Leukemia: 31.4;lymphoma: 11.6" "Adrenal gland - Adrenal cortex cells, Spleen - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA043939, HPA073731" Approved Nucleoplasm,Nucleoli NA NA "Cluster 80: Thymus - Adaptive immune response" "Cluster 6: Leukemia - Signal transduction" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 12 Nucleoplasm Nucleoli "HPA043939: , HPA073731: " "unprognostic (3.22e-1)" "potential prognostic unfavorable (5.27e-5)" "unprognostic (2.05e-2)" "potential prognostic favorable (2.16e-5)" "potential prognostic favorable (6.84e-4)" "unprognostic (1.94e-2)" "unprognostic (1.02e-1)" "unprognostic (1.09e-1)" RAG2 ENSG00000175097 "Recombination activating 2" P55895 11 36575574-36598279 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA recombination" "Chromatin regulator" "Disease variant, SCID" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "lymphoid tissue: 139.8" "Cell type enhanced" "Detected in some" "Adipocytes: 9.0;Cardiomyocytes: 27.0;Choroid plexus epithelial cells: 4.0;Epicardial cells: 4.5;Fibro-adipogenic progenitors: 2.6;Late primary spermatocytes: 4.9" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 4.9" "Cancer enriched" "Detected in single" 23 "Thyroid Carcinoma (TCGA): 2.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 56 "Leukemia: 14.1;lymphoma: 10.5" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA065704 Approved Nucleoplasm NA NA "Cluster 80: Thymus - Adaptive immune response" "Cluster 6: Leukemia - Signal transduction" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 3 Nucleoplasm "HPA065704: " "unprognostic (2.15e-3)" RAI1 "DKFZP434A139, KIAA1820, MGC12824, SMCR, SMS" ENSG00000108557 "Retinoic acid induced 1" Q7Z5J4 17 17681458-17811453 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Papillary tip epithelial cells: 174.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023898, HPA054906" Approved Enhanced Nucleoplasm NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 28 Nucleoplasm "HPA023898: , HPA054906: " "unprognostic (8.70e-3)" "unprognostic (2.77e-2)" "unprognostic (1.26e-3)" "unprognostic (1.51e-2)" "unprognostic (1.37e-1)" "unprognostic (1.86e-1)" "unprognostic (1.77e-2)" "unprognostic (7.13e-2)" "unprognostic (5.25e-2)" "unprognostic (2.77e-2)" "unprognostic (6.05e-3)" "unprognostic (3.83e-3)" "unprognostic (3.20e-1)" "unprognostic (4.22e-3)" "unprognostic (3.02e-1)" "unprognostic (1.98e-1)" "unprognostic (2.17e-1)" "unprognostic (1.22e-1)" "unprognostic (4.45e-2)" "unprognostic (7.72e-3)" "unprognostic (2.42e-1)" "unprognostic (6.38e-2)" "potential prognostic unfavorable (6.44e-4)" "unprognostic (7.08e-2)" "unprognostic (9.24e-2)" "unprognostic (6.56e-2)" "unprognostic (5.02e-2)" "unprognostic (4.40e-2)" "unprognostic (2.62e-1)" "unprognostic (9.89e-3)" "unprognostic (6.11e-2)" RAI14 "DKFZp564G013, KIAA1334, NORPEG, RAI13" ENSG00000039560 "Retinoic acid induced 14" Q9P0K7 5 34656328-34832612 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 356.7;Conjunctival goblet cells: 415.5;Early spermatids: 392.3;Late spermatids: 575.4;Salivary duct cells: 419.0;Syncytiotrophoblasts: 571.7;Urothelial cells: 329.0" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 191.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "spinal cord: 31.4" "HPA036949, HPA036950" Supported Supported "Nucleoplasm,Actin filaments,Cytosol" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 30: White matter - Myelination" "Cluster 72: Neuronal - Signal transduction" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 53 Nucleoplasm "Actin filaments, Cytosol" "HPA036949: , HPA036950: " "unprognostic (1.92e-2)" "unprognostic (1.80e-1)" "unprognostic (2.46e-1)" "unprognostic (5.37e-3)" "unprognostic (1.39e-1)" "unprognostic (1.02e-1)" "unprognostic (9.93e-2)" "unprognostic (6.39e-2)" "unprognostic (3.66e-2)" "unprognostic (1.14e-2)" "potential prognostic favorable (7.36e-5)" "unprognostic (1.93e-2)" "unprognostic (2.64e-3)" "unprognostic (8.40e-2)" "unprognostic (1.26e-1)" "unprognostic (6.91e-2)" "unprognostic (1.99e-2)" "unprognostic (1.60e-1)" "unprognostic (3.30e-3)" "unprognostic (5.36e-2)" "unprognostic (1.18e-2)" "unprognostic (1.01e-1)" "unprognostic (3.74e-3)" "unprognostic (2.52e-1)" "unprognostic (4.17e-1)" "unprognostic (6.91e-3)" "unprognostic (9.86e-3)" "potential prognostic unfavorable (9.34e-4)" "unprognostic (2.41e-1)" "unprognostic (1.56e-2)" "unprognostic (2.03e-1)" RAI2 ENSG00000131831 "Retinoic acid induced 2" Q9Y5P3 X 17800049-17861337 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 79.4;Endometrial luminal cells: 120.8;Peritubular myoid cells: 77.7;Salivary myoepithelial cells: 77.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD8 T-cell: 1.8" "Lineage enriched" "Detected in single" 10 "T-cells: 1.8" "Cancer enhanced" "Detected in some" "Rhabdoid: 21.1" "Pituitary gland - Corticotropes, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051054 Uncertain Approved "Plasma membrane" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 75: Ovary - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 5: Rhabdoid - Unknown function" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 20 "Plasma membrane" "HPA051054: " "unprognostic (5.20e-3)" "unprognostic (1.37e-1)" "unprognostic (4.49e-2)" "unprognostic (1.75e-1)" "unprognostic (1.48e-1)" "unprognostic (1.97e-2)" "unprognostic (5.07e-1)" "unprognostic (1.93e-3)" "unprognostic (4.42e-2)" "unprognostic (1.75e-3)" "potential prognostic favorable (1.20e-8)" "unprognostic (8.65e-3)" "unprognostic (1.47e-2)" "unprognostic (7.59e-2)" "potential prognostic favorable (4.84e-4)" "unprognostic (1.12e-2)" "unprognostic (6.88e-2)" "unprognostic (3.10e-2)" "unprognostic (2.58e-1)" "unprognostic (1.04e-1)" "unprognostic (1.99e-1)" "potential prognostic favorable (4.22e-4)" "unprognostic (1.76e-1)" "unprognostic (2.72e-2)" "unprognostic (1.51e-2)" "potential prognostic favorable (3.22e-4)" "unprognostic (2.16e-1)" "unprognostic (2.03e-2)" "unprognostic (2.55e-1)" "unprognostic (1.24e-1)" "unprognostic (2.46e-1)" RALA RAL ENSG00000006451 "RAS like proto-oncogene A" P11233 7 39623565-39708120 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Cell cycle, Cell division, Exocytosis" Hydrolase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial glandular cells: 461.5;Endometrial secretory cells: 445.0;Esophageal apical cells: 1857.8;Esophageal suprabasal cells: 532.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047037, HPA065232" Approved Supported "Plasma membrane,Focal adhesion sites" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 7: Non-specific - Ribosome" "Cluster 67: Non-specific - Unknown function" "Cluster 51: Secretory epithelial cells - Mixed function" 27 "Plasma membrane" "Focal adhesion sites" "HPA047037: , HPA065232: " "unprognostic (2.38e-1)" "unprognostic (2.56e-2)" "unprognostic (2.58e-3)" "potential prognostic unfavorable (3.66e-4)" "unprognostic (8.24e-2)" "unprognostic (4.30e-2)" "unprognostic (1.17e-1)" "unprognostic (1.62e-3)" "unprognostic (1.37e-1)" "unprognostic (3.26e-3)" "potential prognostic favorable (2.01e-5)" "unprognostic (2.55e-2)" "unprognostic (2.11e-1)" "validated prognostic unfavorable (2.74e-5)" "validated prognostic unfavorable (2.23e-5)" "unprognostic (3.06e-2)" "unprognostic (1.06e-2)" "unprognostic (1.26e-1)" "unprognostic (5.18e-2)" "unprognostic (1.13e-1)" "unprognostic (7.36e-2)" "unprognostic (2.18e-3)" "unprognostic (4.55e-3)" "unprognostic (2.03e-1)" "unprognostic (1.34e-1)" "unprognostic (3.21e-1)" "unprognostic (6.79e-2)" "unprognostic (7.94e-2)" "unprognostic (3.61e-2)" "unprognostic (1.32e-1)" "unprognostic (2.22e-1)" RALB ENSG00000144118 "RAS like proto-oncogene B" P11234 2 120240064-120294710 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Cell cycle, Cell division" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "parathyroid gland: 315.6" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 374.6;Extravillous trophoblasts: 213.8;Megakaryocytes: 358.5;Neutrophil progenitors: 232.8;Neutrophils: 910.2;Oocytes: 313.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 380.1" "Group enriched" "Detected in all" 4 "granulocytes: 380.1;monocytes: 177.0" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026010, HPA065232" Enhanced NA NA 130000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 20 "CAB026010: , HPA065232: " "unprognostic (8.42e-2)" "unprognostic (9.26e-2)" "unprognostic (8.45e-2)" "unprognostic (1.33e-1)" "unprognostic (6.23e-2)" "unprognostic (2.23e-2)" "unprognostic (4.76e-2)" "unprognostic (1.98e-3)" "unprognostic (1.77e-2)" "unprognostic (6.01e-2)" "validated prognostic favorable (1.95e-9)" "validated prognostic favorable (4.89e-5)" "unprognostic (5.09e-2)" "unprognostic (1.09e-2)" "unprognostic (1.42e-1)" "potential prognostic unfavorable (4.10e-4)" "unprognostic (1.21e-3)" "unprognostic (3.56e-1)" "unprognostic (3.38e-2)" "unprognostic (3.18e-1)" "potential prognostic unfavorable (8.96e-4)" "unprognostic (3.74e-3)" "unprognostic (4.87e-3)" "unprognostic (1.34e-1)" "unprognostic (1.61e-1)" "unprognostic (6.26e-2)" "unprognostic (1.41e-1)" "unprognostic (1.35e-1)" "unprognostic (2.01e-1)" "unprognostic (1.70e-1)" "unprognostic (1.13e-1)" RALBP1 "RIP, RIP1, RLIP76" ENSG00000017797 "RalA binding protein 1" Q15311 18 9475009-9538114 "Enzymes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins, Transporters" Transport "GTPase activation, Translocase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 513.9;Esophageal suprabasal cells: 395.9;Extravillous trophoblasts: 783.6;Renal collecting duct principal cells: 465.3;Urothelial cells: 385.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 10 "neutrophil: 196.5" "Lineage enriched" "Detected in all" 10 "granulocytes: 196.5" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007622, CAB046010, HPA046651" Approved Supported "Nucleoplasm,Nuclear bodies,Plasma membrane" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 58: Skin - Keratinization" "Cluster 55: Non-specific - Transcription" "Cluster 13: Non-specific - Mixed function" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 104 "Nucleoplasm, Plasma membrane" "Nuclear bodies" "CAB046010: , HPA007622: , HPA046651: " "unprognostic (3.71e-2)" "unprognostic (2.23e-1)" "unprognostic (3.38e-1)" "unprognostic (1.52e-3)" "unprognostic (2.40e-1)" "unprognostic (4.77e-3)" "unprognostic (1.85e-1)" "unprognostic (1.69e-1)" "unprognostic (1.78e-1)" "unprognostic (4.79e-2)" "validated prognostic favorable (5.92e-6)" "validated prognostic favorable (2.07e-4)" "unprognostic (2.52e-1)" "unprognostic (2.52e-2)" "unprognostic (3.69e-3)" "unprognostic (2.09e-3)" "unprognostic (4.38e-1)" "unprognostic (1.09e-1)" "unprognostic (7.73e-2)" "unprognostic (2.53e-2)" "unprognostic (1.34e-1)" "unprognostic (1.30e-3)" "unprognostic (8.32e-2)" "unprognostic (2.12e-1)" "unprognostic (1.58e-1)" "unprognostic (4.01e-1)" "unprognostic (1.55e-1)" "unprognostic (1.50e-1)" "unprognostic (2.42e-1)" "unprognostic (2.14e-1)" "unprognostic (1.43e-1)" RALGAPA1 "DKFZp667F074, GARNL1, GRIPE, KIAA0884, RalGAPalpha1, Tulip1" ENSG00000174373 "Ral GTPase activating protein catalytic subunit alpha 1" Q6GYQ0 14 35538352-35809304 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "GTPase activation" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000851 Approved Approved "Mitochondria,Cytosol,Mid piece,Principal piece" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 25: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 7 Cytosol "Mitochondria, Mid piece, Principal piece" "HPA000851: " "unprognostic (1.88e-3)" "unprognostic (4.33e-1)" "unprognostic (1.27e-1)" "unprognostic (7.36e-3)" "unprognostic (5.34e-2)" "unprognostic (1.73e-1)" "unprognostic (1.22e-2)" "unprognostic (5.25e-2)" "unprognostic (9.40e-2)" "unprognostic (7.62e-2)" "potential prognostic favorable (9.66e-6)" "unprognostic (1.91e-3)" "unprognostic (1.17e-1)" "unprognostic (4.28e-1)" "unprognostic (7.27e-2)" "unprognostic (1.05e-1)" "unprognostic (2.21e-1)" "unprognostic (1.74e-1)" "unprognostic (3.09e-1)" "unprognostic (6.40e-2)" "unprognostic (8.15e-2)" "unprognostic (4.46e-3)" "unprognostic (1.01e-2)" "unprognostic (1.74e-1)" "unprognostic (2.78e-1)" "unprognostic (2.17e-1)" "unprognostic (1.18e-1)" "unprognostic (1.10e-1)" "unprognostic (1.70e-1)" "unprognostic (3.43e-1)" "unprognostic (7.27e-2)" RALGAPA2 "AS250, C20orf74, dJ1049G11.4, KIAA1272, RapGAPalpha2" ENSG00000188559 "Ral GTPase activating protein catalytic subunit alpha 2" Q2PPJ7 20 20389530-20712644 "Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Lymphatic endothelial cells: 997.3;Myonuclei: 1448.9;Neutrophil progenitors: 1427.0;Neutrophils: 3116.4;Vascular endothelial cells: 1005.6" "Cell type enhanced" "Detected in all" "midbrain-derived inhibitory: 778.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pituitary gland - Corticotropes, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042707, HPA043622" Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 24: Neutrophils - Innate immunity signal integration" 4 "Plasma membrane, Cytosol" "HPA042707: , HPA043622: " "unprognostic (2.79e-2)" "unprognostic (4.97e-2)" "unprognostic (8.23e-2)" "unprognostic (2.00e-2)" "unprognostic (1.77e-2)" "unprognostic (2.72e-1)" "unprognostic (3.57e-1)" "unprognostic (2.19e-1)" "unprognostic (1.27e-1)" "unprognostic (3.26e-3)" "unprognostic (1.17e-3)" "unprognostic (5.32e-2)" "unprognostic (4.58e-2)" "unprognostic (9.49e-2)" "unprognostic (1.48e-1)" "unprognostic (3.85e-2)" "unprognostic (2.68e-1)" "potential prognostic unfavorable (5.27e-4)" "unprognostic (1.99e-1)" "unprognostic (5.26e-3)" "unprognostic (3.51e-1)" "unprognostic (1.24e-1)" "unprognostic (2.21e-1)" "unprognostic (1.29e-1)" "unprognostic (2.22e-2)" "unprognostic (6.16e-2)" "unprognostic (3.20e-1)" "unprognostic (7.89e-2)" "unprognostic (2.89e-1)" "unprognostic (1.35e-1)" "unprognostic (3.31e-1)" RALGAPB "DKFZp781M2411, KIAA1219, RalGAPbeta" ENSG00000170471 "Ral GTPase activating protein non-catalytic subunit beta" Q86X10 20 38472816-38578859 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051454 Approved Approved "Nuclear speckles" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 31: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 7: Non-specific - Transcription" 10 "Nuclear speckles" "HPA051454: " "unprognostic (2.74e-2)" "unprognostic (1.51e-1)" "unprognostic (9.52e-2)" "unprognostic (1.43e-1)" "unprognostic (5.15e-2)" "unprognostic (3.42e-2)" "unprognostic (2.39e-1)" "unprognostic (5.04e-2)" "unprognostic (8.12e-2)" "unprognostic (4.50e-2)" "potential prognostic favorable (2.26e-5)" "unprognostic (1.18e-2)" "unprognostic (2.17e-1)" "unprognostic (3.76e-3)" "unprognostic (9.60e-2)" "unprognostic (3.12e-1)" "unprognostic (2.69e-2)" "unprognostic (6.52e-3)" "unprognostic (1.52e-1)" "potential prognostic unfavorable (7.36e-4)" "unprognostic (3.37e-3)" "unprognostic (4.89e-2)" "potential prognostic unfavorable (5.80e-4)" "unprognostic (1.58e-1)" "unprognostic (6.22e-3)" "unprognostic (9.79e-3)" "unprognostic (2.53e-1)" "unprognostic (2.26e-1)" "unprognostic (2.85e-1)" "unprognostic (1.60e-1)" "unprognostic (3.96e-2)" RALGDS "RalGEF, RGDS, RGF" ENSG00000160271 "Ral guanine nucleotide dissociation stimulator" Q12967 9 133097720-133149334 "Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 142.0;Ocular epithelial cells: 179.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "gdT-cell: 24.0;MAIT T-cell: 9.7;memory CD4 T-cell: 10.9;memory CD8 T-cell: 17.6;naive CD8 T-cell: 9.1;NK-cell: 9.1;T-reg: 20.8" "Group enriched" "Detected in many" 7 "NK-cells: 9.1;T-cells: 24.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025961, CAB032582" Approved Uncertain Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 59: Leukemia - T-cell receptor" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 14 Nucleoplasm "CAB032582: , HPA025961: " "unprognostic (2.76e-1)" "unprognostic (2.06e-2)" "unprognostic (3.42e-1)" "unprognostic (3.71e-2)" "unprognostic (6.52e-2)" "unprognostic (6.71e-2)" "unprognostic (3.50e-1)" "potential prognostic favorable (4.72e-4)" "unprognostic (3.79e-1)" "unprognostic (3.38e-1)" "potential prognostic favorable (7.97e-4)" "unprognostic (1.59e-2)" "unprognostic (7.41e-3)" "unprognostic (9.11e-2)" "unprognostic (5.13e-2)" "unprognostic (3.31e-2)" "unprognostic (1.51e-1)" "unprognostic (2.92e-2)" "unprognostic (8.86e-3)" "unprognostic (9.38e-2)" "unprognostic (1.35e-2)" "unprognostic (2.29e-2)" "unprognostic (1.25e-1)" "unprognostic (5.02e-2)" "unprognostic (1.88e-1)" "unprognostic (1.13e-2)" "unprognostic (4.97e-2)" "unprognostic (6.88e-2)" "unprognostic (1.52e-1)" "unprognostic (3.16e-2)" "unprognostic (2.00e-2)" RALGPS1 "KIAA0351, RALGEF2, RALGPS1A" ENSG00000136828 "Ral GEF with PH domain and SH3 binding motif 1" Q5JS13 9 126914774-127223166 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gonadotrophs: 319.9;Rod photoreceptor cells: 322.4;Thyrotrophs: 346.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory B-cell: 2.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Stomach - Gastric mucous cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014749 Uncertain NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 30: White matter - Myelination" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" "HPA014749: " "unprognostic (1.13e-2)" "unprognostic (3.07e-2)" "unprognostic (2.22e-3)" "unprognostic (1.72e-1)" "unprognostic (9.55e-2)" "unprognostic (5.02e-2)" "unprognostic (1.81e-1)" "unprognostic (3.13e-3)" "unprognostic (5.47e-2)" "unprognostic (2.45e-1)" "potential prognostic favorable (9.66e-5)" "unprognostic (1.54e-3)" "unprognostic (1.45e-2)" "unprognostic (3.26e-1)" "unprognostic (1.67e-2)" "unprognostic (1.11e-2)" "unprognostic (6.23e-3)" "unprognostic (8.14e-2)" "unprognostic (9.93e-3)" "unprognostic (4.17e-2)" "unprognostic (4.43e-1)" "unprognostic (1.26e-2)" "unprognostic (2.78e-1)" "unprognostic (2.11e-1)" "unprognostic (7.54e-3)" "unprognostic (3.80e-2)" "unprognostic (3.34e-1)" "unprognostic (4.77e-2)" "unprognostic (1.05e-1)" "unprognostic (8.26e-2)" "unprognostic (3.78e-2)" RALGPS2 "FLJ10244, FLJ25604, KIAA0351" ENSG00000116191 "Ral GEF with PH domain and SH3 binding motif 2" Q86X27 1 178725165-178921842 "Disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Alzheimer disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 48.9;retina: 49.8;testis: 67.0" "Cell type enhanced" "Detected in all" "B-cells: 1377.7;Rod photoreceptor cells: 824.1;Urothelial cells: 632.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "memory B-cell: 29.0;naive B-cell: 23.9" "Lineage enriched" "Detected in many" 11 "B-cells: 29.0" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Colon - Enteric glia cells, Liver - Hepatocytes, Spleen - B-cells (Spleen), Stomach - Gastric mucous cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027143, HPA028328" Enhanced Uncertain Nucleoplasm,Cytosol NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 29: Forebrain - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 23 "Nucleoplasm, Cytosol" "HPA027143: , HPA028328: " "unprognostic (4.05e-2)" "unprognostic (2.78e-2)" "unprognostic (1.60e-1)" "unprognostic (3.55e-3)" "unprognostic (7.06e-3)" "unprognostic (2.78e-1)" "unprognostic (1.78e-1)" "unprognostic (2.35e-2)" "unprognostic (4.37e-2)" "unprognostic (2.09e-1)" "unprognostic (1.45e-2)" "unprognostic (9.74e-2)" "unprognostic (8.56e-3)" "unprognostic (1.06e-1)" "unprognostic (2.38e-1)" "unprognostic (2.35e-3)" "unprognostic (8.96e-3)" "unprognostic (2.77e-1)" "unprognostic (7.93e-2)" "unprognostic (1.47e-1)" "unprognostic (1.71e-2)" "unprognostic (5.81e-2)" "potential prognostic unfavorable (9.29e-4)" "unprognostic (5.85e-2)" "unprognostic (2.24e-2)" "unprognostic (1.52e-1)" "unprognostic (6.97e-2)" "unprognostic (1.87e-1)" "unprognostic (1.15e-1)" "unprognostic (2.76e-2)" "unprognostic (2.21e-2)" RALY "HNRPCL2, P542" ENSG00000125970 "RALY heterogeneous nuclear ribonucleoprotein" Q9UKM9 20 33993646-34108308 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040971, HPA043614" Enhanced Enhanced Nucleoplasm,Vesicles NA NA 7900 "Cluster 7: Non-specific - Innate immune response" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 62: Non-specific - Plasma proteins" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 81 Nucleoplasm Vesicles "HPA040971: , HPA043614: " "unprognostic (5.34e-2)" "unprognostic (3.96e-2)" "unprognostic (4.62e-1)" "unprognostic (9.09e-2)" "unprognostic (1.92e-1)" "unprognostic (1.61e-1)" "unprognostic (3.62e-2)" "unprognostic (1.08e-1)" "unprognostic (3.28e-2)" "unprognostic (4.52e-2)" "potential prognostic favorable (1.74e-4)" "unprognostic (1.47e-1)" "unprognostic (3.93e-1)" "unprognostic (1.02e-3)" "potential prognostic unfavorable (3.87e-6)" "unprognostic (2.44e-1)" "unprognostic (9.52e-3)" "unprognostic (1.05e-2)" "unprognostic (1.66e-1)" "unprognostic (4.30e-2)" "unprognostic (5.54e-2)" "unprognostic (3.15e-2)" "unprognostic (7.34e-2)" "unprognostic (1.31e-2)" "unprognostic (1.35e-2)" "unprognostic (1.18e-2)" "unprognostic (3.76e-1)" "unprognostic (6.27e-2)" "unprognostic (2.26e-1)" "unprognostic (1.23e-1)" "unprognostic (1.99e-1)" RALYL HNRPCL3 ENSG00000184672 "RALY RNA binding protein like" Q86SE5 8 84182787-84921844 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 18.7;brain: 52.6;kidney: 17.9" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 3795.8;Adrenal medulla cells: 2063.6;Brain excitatory neurons: 2787.3;Brain inhibitory neurons: 1868.9;Corticotrophs: 958.4;Lactotrophs: 1565.3;Oligodendrocyte progenitor cells: 1183.9;Other brain neurons: 2386.8;Pituitary stem cells: 887.8;Proximal tubule cells: 785.3;Renal connecting tubule cells: 1091.1;Retinal amacrine cells: 1337.6;Retinal ganglion cells: 1402.2;Somatotrophs: 1457.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 4.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 4.1" "Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055868, HPA059112" Enhanced Enhanced Nucleoplasm NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 2: Neurons - Nucleosome" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 17 Nucleoplasm "HPA055868: , HPA059112: " "unprognostic (1.04e-1)" "unprognostic (3.10e-1)" "unprognostic (2.90e-2)" "unprognostic (1.03e-2)" "unprognostic (1.93e-2)" RAMAC "C15orf18, FAM103A1, HsT19360, MGC2560, RAM, RAMMET" ENSG00000169612 "RNA guanine-7 methyltransferase activating subunit" Q9BTL3 15 82986210-82991057 "Predicted intracellular proteins" "mRNA capping, mRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 38.9;Late primary spermatocytes: 49.3" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "HPA041923, HPA041948" Supported Supported Nucleoplasm No No "Cluster 35: Neutrophils - Protein binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" 50 Nucleoplasm "HPA041923: , HPA041948: " "unprognostic (9.65e-2)" "unprognostic (1.58e-1)" "unprognostic (2.66e-3)" "unprognostic (7.75e-3)" "unprognostic (8.38e-3)" "unprognostic (7.87e-2)" "unprognostic (5.42e-3)" "unprognostic (4.75e-2)" "unprognostic (3.22e-1)" "unprognostic (3.99e-3)" "unprognostic (5.79e-2)" "unprognostic (4.65e-2)" "unprognostic (4.36e-1)" "unprognostic (2.19e-3)" "unprognostic (2.54e-3)" "unprognostic (1.07e-3)" "unprognostic (1.29e-1)" "unprognostic (1.10e-2)" "unprognostic (1.61e-1)" "unprognostic (8.37e-2)" "unprognostic (1.14e-2)" "unprognostic (1.60e-2)" "unprognostic (2.72e-1)" "unprognostic (2.22e-1)" "unprognostic (2.12e-1)" "unprognostic (2.60e-1)" "unprognostic (1.45e-1)" "unprognostic (4.96e-2)" "unprognostic (1.80e-1)" RAMACL "C6orf119, dJ427A4.2, FAM103A2P, RAMMETL" ENSG00000235272 "RNA guanine-7 methyltransferase activating subunit like (pseudogene)" 6 166583009-166586678 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "HPA041923, HPA041948" Uncertain Approved Nucleoplasm No NA "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" Nucleoplasm "HPA041923: , HPA041948: " "unprognostic (3.99e-1)" "unprognostic (3.50e-1)" RAMP1 ENSG00000132329 "Receptor activity modifying protein 1" O60894 2 237858893-237912106 "FDA approved drug targets, Predicted membrane proteins, Transporters" Transport Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 533.5;endometrium 1: 693.9" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 2218.0;Endometrial stromal cells: 455.2;Epididymal efferent duct absorptive cells: 407.1;Epididymal principal cells: 422.9;Hepatic stellate cells: 355.0;Paneth cells: 328.7;Smooth muscle cells: 816.6;Thymic myoid cells: 552.0" "Cell type enhanced" "Detected in all" "oligodendrocyte precursor cell: 172.9" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 334.5;Prostate Adenocarcinoma (TCGA): 361.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 18 "NK-cell: 70.4" "Lineage enriched" "Detected in many" 18 "NK-cells: 70.4" "Cancer enhanced" "Detected in many" "prostate cancer: 147.8" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal medulla cells, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057814 Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 39: Astrocytes - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 62: Smooth muscle cells - Muscle contraction" 7 "Nucleoplasm, Nuclear membrane" "HPA057814: " "unprognostic (1.79e-2)" "unprognostic (3.83e-2)" "unprognostic (2.22e-1)" "unprognostic (2.20e-1)" "unprognostic (2.96e-2)" "unprognostic (1.89e-2)" "unprognostic (3.84e-1)" "unprognostic (2.35e-2)" "unprognostic (9.64e-2)" "unprognostic (5.50e-2)" "unprognostic (1.34e-1)" "unprognostic (1.29e-1)" "unprognostic (5.77e-2)" "unprognostic (1.04e-3)" "unprognostic (4.77e-2)" "unprognostic (1.11e-1)" "unprognostic (5.21e-3)" "unprognostic (1.22e-1)" "unprognostic (1.18e-1)" "unprognostic (9.47e-3)" "unprognostic (2.80e-1)" "unprognostic (1.33e-1)" "unprognostic (3.42e-1)" "unprognostic (7.22e-2)" "unprognostic (4.28e-3)" "unprognostic (1.68e-1)" "unprognostic (2.01e-1)" "potential prognostic unfavorable (3.38e-5)" "unprognostic (2.78e-1)" "unprognostic (3.64e-2)" "unprognostic (5.08e-2)" RAMP2 ENSG00000131477 "Receptor activity modifying protein 2" O60895 17 42758447-42763041 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Decidual stromal cells: 207.5;Fibroblasts: 178.1;Lymphatic endothelial cells: 443.5;Vascular endothelial cells: 547.2" "Cell type enriched" "Detected in many" 7 "endothelial cell: 400.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 21 "plasmacytoid DC: 2.9" "Lineage enriched" "Detected in single" 21 "dendritic cells: 2.9" "Cancer enhanced" "Detected in many" "Neuroblastoma: 25.4" "Adrenal gland - Endothelial cells, Liver - Vascular endothelial cells, Skin - Fibroblasts_2, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052020 Approved Vesicles NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 18: Liver cancer - Metabolism" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 3 Vesicles "HPA052020: " "unprognostic (2.41e-3)" "unprognostic (1.68e-1)" "unprognostic (1.12e-1)" "unprognostic (1.70e-1)" "unprognostic (3.74e-2)" "unprognostic (2.99e-1)" "unprognostic (1.16e-1)" "unprognostic (2.66e-1)" "potential prognostic favorable (6.63e-4)" "unprognostic (2.69e-1)" "validated prognostic favorable (5.19e-5)" "validated prognostic favorable (1.07e-5)" "potential prognostic unfavorable (1.30e-4)" "unprognostic (5.96e-2)" "unprognostic (5.30e-3)" "unprognostic (7.09e-2)" "unprognostic (1.92e-1)" "unprognostic (1.72e-1)" "unprognostic (2.40e-1)" "unprognostic (1.47e-1)" "unprognostic (1.19e-1)" "unprognostic (1.37e-2)" "unprognostic (6.67e-3)" "unprognostic (1.59e-2)" "unprognostic (1.72e-2)" "unprognostic (7.80e-2)" "unprognostic (8.37e-3)" "unprognostic (3.87e-3)" "unprognostic (1.72e-2)" "unprognostic (3.20e-1)" "unprognostic (1.46e-2)" RAMP3 ENSG00000122679 "Receptor activity modifying protein 3" O60896 7 45157791-45186302 "FDA approved drug targets, Predicted membrane proteins, Transporters" Transport Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Decidual stromal cells: 29.9;Hepatic stellate cells: 51.6;Lymphatic endothelial cells: 184.9;Podocytes: 87.0;Vascular endothelial cells: 409.5" "Cell type enriched" "Detected in many" 6 "endothelial cell: 143.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Bone cancer: 12.3;breast cancer: 4.4" "Adrenal gland - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Sinusoid Endothelial cells, Minor Salivary Gland - Endothelial cells, Pituitary gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells" "Group enriched" "Detected in all" 4 "cerebellum: 62.2;cerebral cortex: 49.2;thalamus: 175.0;white matter: 60.1" "Low region specificity" "Detected in all" HPA075527 Supported "Plasma membrane" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 30: White matter - Myelination" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 107 "Plasma membrane" "HPA075527: " "unprognostic (1.46e-2)" "unprognostic (1.16e-2)" "unprognostic (1.06e-1)" "unprognostic (9.01e-3)" "unprognostic (8.51e-2)" "unprognostic (2.05e-2)" "unprognostic (2.32e-2)" "unprognostic (3.35e-2)" "potential prognostic favorable (3.96e-4)" "unprognostic (8.54e-2)" "validated prognostic favorable (1.47e-12)" "validated prognostic favorable (5.33e-5)" "unprognostic (2.21e-2)" "validated prognostic favorable (3.56e-7)" "validated prognostic favorable (3.93e-8)" "unprognostic (9.46e-2)" "unprognostic (1.82e-2)" "unprognostic (1.82e-1)" "unprognostic (2.41e-1)" "unprognostic (2.93e-1)" "unprognostic (1.17e-1)" "unprognostic (3.10e-2)" "unprognostic (1.35e-1)" "unprognostic (2.43e-2)" "unprognostic (1.87e-1)" "unprognostic (1.23e-1)" "unprognostic (1.22e-1)" "unprognostic (2.18e-3)" "unprognostic (5.93e-2)" "unprognostic (3.05e-1)" "unprognostic (1.90e-1)" RAN "ARA24, Gsp1, TC4" ENSG00000132341 "RAN, member RAS oncogene family" P62826 12 130872037-130877678 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Host-virus interaction, Mitosis, Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal basal cells: 1497.6;Esophageal suprabasal cells: 1062.0;Extravillous trophoblasts: 1365.9;Gastric progenitor cells: 906.1;Late primary spermatocytes: 1000.7;Migrating cytotrophoblasts: 1241.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063353 Supported Nucleoplasm No No 5400000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 39: Testis - Nuclear processes" "Cluster 21: Non-specific - Metabolism" "Cluster 38: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 272 Nucleoplasm "HPA063353: " "potential prognostic unfavorable (1.12e-4)" "unprognostic (1.23e-1)" "unprognostic (2.60e-1)" "unprognostic (7.04e-3)" "unprognostic (1.19e-2)" "unprognostic (1.99e-1)" "unprognostic (3.08e-1)" "unprognostic (2.46e-1)" "potential prognostic unfavorable (5.48e-4)" "unprognostic (4.52e-2)" "potential prognostic favorable (2.83e-4)" "potential prognostic unfavorable (6.89e-4)" "unprognostic (1.14e-3)" "validated prognostic unfavorable (1.96e-10)" "validated prognostic unfavorable (3.56e-8)" "potential prognostic unfavorable (1.93e-5)" "unprognostic (1.30e-3)" "unprognostic (9.10e-2)" "unprognostic (3.31e-1)" "unprognostic (1.46e-2)" "unprognostic (4.29e-1)" "unprognostic (5.74e-3)" "unprognostic (5.60e-2)" "unprognostic (5.50e-3)" "unprognostic (1.17e-1)" "unprognostic (2.77e-2)" "unprognostic (3.37e-1)" "unprognostic (1.26e-1)" "unprognostic (6.57e-2)" "unprognostic (3.09e-1)" "unprognostic (2.88e-1)" RANBP1 HTF9A ENSG00000099901 "RAN binding protein 1" P43487 22 20115938-20127355 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Differentiating spermatogonia: 594.9;Esophageal basal cells: 629.8;Extravillous trophoblasts: 813.8;Gastric progenitor cells: 505.0;Late primary spermatocytes: 775.7;Migrating cytotrophoblasts: 719.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065868, HPA065931" Supported Enhanced Cytosol NA NA 2400000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 27: Non-specific - Cell proliferation" 59 Cytosol "HPA065868: , HPA065931: " "unprognostic (6.53e-2)" "unprognostic (2.00e-1)" "unprognostic (7.12e-2)" "unprognostic (9.59e-2)" "unprognostic (4.67e-2)" "unprognostic (3.02e-1)" "unprognostic (2.05e-2)" "unprognostic (5.87e-2)" "unprognostic (2.50e-3)" "unprognostic (2.85e-3)" "unprognostic (1.70e-3)" "unprognostic (5.78e-2)" "unprognostic (6.27e-2)" "validated prognostic unfavorable (1.24e-9)" "validated prognostic unfavorable (1.86e-7)" "potential prognostic unfavorable (3.53e-4)" "unprognostic (2.81e-3)" "unprognostic (3.44e-2)" "unprognostic (3.88e-2)" "unprognostic (3.48e-2)" "unprognostic (3.10e-2)" "unprognostic (1.32e-2)" "unprognostic (3.07e-2)" "unprognostic (6.46e-2)" "unprognostic (5.64e-3)" "unprognostic (3.63e-3)" "unprognostic (1.25e-1)" "unprognostic (5.62e-2)" "unprognostic (2.11e-1)" "unprognostic (3.59e-1)" "unprognostic (9.61e-2)" RANBP10 KIAA1464 ENSG00000141084 "RAN binding protein 10" Q6VN20 16 67723070-67806560 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythrocyte progenitors: 178.7;Myonuclei: 164.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 15: Non-specific - Transcription" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 55: Myocytes - Oxidative muscle function" 70 "unprognostic (1.84e-1)" "unprognostic (9.65e-2)" "unprognostic (1.89e-1)" "unprognostic (2.09e-2)" "unprognostic (1.08e-1)" "unprognostic (3.88e-2)" "unprognostic (6.74e-2)" "unprognostic (1.31e-2)" "unprognostic (8.95e-2)" "unprognostic (2.94e-1)" "potential prognostic favorable (1.96e-4)" "unprognostic (8.67e-2)" "unprognostic (1.17e-3)" "unprognostic (2.19e-1)" "potential prognostic favorable (9.34e-5)" "unprognostic (1.68e-1)" "unprognostic (2.60e-1)" "unprognostic (6.67e-3)" "unprognostic (1.16e-1)" "unprognostic (9.77e-2)" "unprognostic (9.25e-2)" "unprognostic (4.50e-2)" "unprognostic (1.21e-2)" "unprognostic (1.99e-2)" "unprognostic (7.50e-3)" "unprognostic (2.11e-1)" "unprognostic (8.47e-2)" "unprognostic (3.14e-1)" "unprognostic (2.47e-1)" "unprognostic (2.77e-3)" "unprognostic (1.48e-2)" RANBP17 ENSG00000204764 "RAN binding protein 17" Q9H2T7 5 170861870-171300015 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 342.8;Alveolar cells type 1: 545.4;Choroid plexus epithelial cells: 468.8" "Cell type enhanced" "Detected in all" "deep-layer near-projecting: 611.2" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029568, HPA029569" Uncertain Approved "Nucleoplasm,Nuclear membrane,Nuclear bodies,Cytosol" Yes No "Cluster 8: Pancreas - Proteolysis" "Cluster 25: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 1 "Nucleoplasm, Nuclear bodies" "Nuclear membrane, Cytosol" "HPA029568: , HPA029569: " "unprognostic (4.09e-2)" "unprognostic (4.41e-2)" "potential prognostic favorable (1.76e-6)" "unprognostic (8.88e-2)" "unprognostic (6.78e-2)" "unprognostic (2.54e-1)" "unprognostic (1.59e-1)" "unprognostic (1.49e-1)" "unprognostic (2.74e-1)" RANBP2 "ADANE, ANE1, NUP358" ENSG00000153201 "RAN binding protein 2" P49792 2 108719482-108785810 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport, Ubl conjugation pathway" "RNA-binding, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Innate lymphoid cells: 547.3;Mast cells: 554.3;pDCs: 537.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018437, HPA018445, HPA023960, CAB034063, HPA049497, HPA051675, HPA067564" Supported Supported "Nucleoplasm,Nuclear membrane,Vesicles,Cytosol" NA NA 41000 "Cluster 1: T-cells - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 103: Non-specific - Basic cellular processes" 93 "Nuclear membrane" "Nucleoplasm, Vesicles, Cytosol" "CAB034063: , HPA018437: , HPA018445: , HPA023960: , HPA049497: , HPA051675: , HPA067564: " "unprognostic (3.51e-1)" "unprognostic (1.30e-1)" "unprognostic (2.15e-1)" "unprognostic (6.22e-2)" "unprognostic (3.80e-1)" "unprognostic (4.66e-2)" "unprognostic (5.09e-2)" "unprognostic (4.63e-2)" "unprognostic (1.59e-1)" "unprognostic (1.09e-2)" "potential prognostic favorable (5.17e-8)" "unprognostic (3.15e-3)" "unprognostic (3.45e-2)" "unprognostic (7.04e-2)" "unprognostic (1.42e-1)" "unprognostic (1.17e-1)" "unprognostic (1.14e-1)" "unprognostic (2.03e-2)" "unprognostic (9.41e-2)" "unprognostic (1.87e-1)" "unprognostic (1.50e-3)" "unprognostic (9.39e-2)" "unprognostic (2.47e-2)" "unprognostic (5.24e-2)" "unprognostic (2.49e-2)" "unprognostic (2.21e-2)" "unprognostic (2.48e-1)" "unprognostic (8.23e-2)" "unprognostic (9.86e-2)" "unprognostic (3.30e-2)" "unprognostic (1.89e-1)" RANBP3 ENSG00000031823 "RAN binding protein 3" Q9H6Z4 19 5916139-5978142 "Cancer-related genes, Predicted intracellular proteins" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 146.1;Late spermatids: 109.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Pancreas - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043375, HPA043389" Enhanced Enhanced Nucleoplasm NA NA 25000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 74: Non-specific - Signal transduction" "Cluster 45: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 13 Nucleoplasm "HPA043375: , HPA043389: " "unprognostic (7.07e-2)" "unprognostic (1.24e-2)" "unprognostic (4.78e-2)" "unprognostic (2.12e-1)" "unprognostic (2.53e-1)" "unprognostic (6.23e-2)" "unprognostic (3.22e-1)" "unprognostic (2.01e-3)" "unprognostic (2.07e-2)" "unprognostic (4.13e-2)" "unprognostic (1.16e-3)" "unprognostic (4.81e-2)" "unprognostic (8.30e-2)" "unprognostic (8.82e-3)" "unprognostic (3.68e-2)" "unprognostic (1.04e-1)" "unprognostic (1.52e-1)" "unprognostic (1.12e-1)" "unprognostic (8.77e-2)" "unprognostic (3.11e-1)" "unprognostic (4.75e-2)" "unprognostic (8.64e-3)" "unprognostic (3.41e-2)" "unprognostic (4.04e-1)" "unprognostic (1.55e-1)" "unprognostic (1.76e-1)" "unprognostic (2.38e-2)" "unprognostic (3.10e-1)" "unprognostic (2.49e-2)" "unprognostic (4.61e-3)" "unprognostic (3.37e-3)" RANBP3L FLJ25422 ENSG00000164188 "RAN binding protein 3 like" Q86VV4 5 36246913-36302114 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.8;kidney: 25.9" "Cell type enhanced" "Detected in many" "Astrocytes: 559.3;Distal convoluted tubule cells: 230.0;Loop of henle epithelial cells: 357.8;Pituitary stem cells: 367.6;Prostatic glandular cells: 89.2;Renal collecting duct intercalated cells: 89.7;Sertoli cells: 143.1;Smooth muscle cells: 116.4;Vascular smooth muscle cells: 83.2" "Cell type enhanced" "Detected in all" "astrocyte: 466.6;fibroblast: 355.3" "Group enriched" "Detected in some" 7 "Breast Invasive Carcinoma (TCGA): 2.9;Glioblastoma Multiforme (TCGA): 7.1;Kidney Chromophobe (TCGA): 8.9;Prostate Adenocarcinoma (TCGA): 9.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 1.6;Rhabdoid: 1.6" "Heart muscle - Smooth muscle cells, Liver - Hepatocytes, Stomach - Parietal cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA037471, HPA037472, HPA061526" Approved Uncertain Nucleoplasm,Cytosol NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 105: Non-specific - Mixed function" 3 Nucleoplasm Cytosol "HPA037471: , HPA037472: , HPA061526: " "unprognostic (9.76e-2)" "unprognostic (2.13e-1)" "unprognostic (7.18e-2)" "unprognostic (3.73e-2)" "unprognostic (1.14e-2)" "potential prognostic favorable (2.16e-4)" "unprognostic (2.29e-1)" "unprognostic (2.26e-1)" "unprognostic (1.28e-1)" RANBP6 ENSG00000137040 "RAN binding protein 6" O60518 9 6011025-6015625 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043748, HPA052684" Approved Supported Vesicles NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 44: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 17: Non-specific - RNA processing" 12 Vesicles "HPA043748: , HPA052684: " "unprognostic (3.52e-1)" "unprognostic (5.01e-2)" "unprognostic (1.97e-1)" "unprognostic (7.62e-2)" "unprognostic (1.51e-1)" "unprognostic (1.03e-1)" "unprognostic (7.65e-2)" "unprognostic (1.22e-2)" "unprognostic (3.76e-1)" "unprognostic (1.48e-2)" "potential prognostic favorable (4.73e-7)" "unprognostic (5.70e-3)" "potential prognostic favorable (2.34e-4)" "unprognostic (2.23e-1)" "unprognostic (1.85e-1)" "unprognostic (1.25e-1)" "unprognostic (5.93e-3)" "unprognostic (1.91e-1)" "unprognostic (2.73e-1)" "unprognostic (1.38e-1)" "unprognostic (1.14e-1)" "unprognostic (6.61e-3)" "unprognostic (1.02e-2)" "unprognostic (2.02e-3)" "unprognostic (5.08e-3)" "unprognostic (2.60e-1)" "unprognostic (2.29e-1)" "unprognostic (3.36e-1)" "unprognostic (2.51e-1)" "unprognostic (8.55e-2)" "unprognostic (2.97e-2)" RANBP9 RanBPM ENSG00000010017 "RAN binding protein 9" Q96S59 6 13621498-13711835 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1328.5;Neutrophil progenitors: 470.7;Neutrophils: 488.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023427, CAB033767, HPA050007, HPA076784" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 39: Testis - Nuclear processes" "Cluster 14: Neurons - Synaptic function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 128 Nucleoplasm "Nuclear bodies, Cytosol" "CAB033767: , HPA023427: , HPA050007: , HPA076784: " "unprognostic (1.05e-1)" "unprognostic (3.84e-2)" "unprognostic (2.40e-1)" "unprognostic (2.79e-1)" "unprognostic (2.60e-1)" "unprognostic (2.82e-2)" "unprognostic (7.72e-2)" "unprognostic (1.18e-2)" "potential prognostic favorable (6.75e-4)" "potential prognostic unfavorable (7.31e-4)" "potential prognostic favorable (1.21e-5)" "unprognostic (6.53e-3)" "unprognostic (1.85e-1)" "unprognostic (2.31e-1)" "unprognostic (1.72e-1)" "unprognostic (8.45e-2)" "unprognostic (1.90e-2)" "unprognostic (5.00e-1)" "unprognostic (1.30e-2)" "unprognostic (1.01e-2)" "unprognostic (4.78e-2)" "unprognostic (2.03e-1)" "unprognostic (1.67e-1)" "unprognostic (2.13e-2)" "unprognostic (5.51e-2)" "unprognostic (8.03e-3)" "unprognostic (4.32e-2)" "unprognostic (2.13e-2)" "unprognostic (3.75e-1)" "unprognostic (2.26e-1)" "unprognostic (2.98e-1)" RANGAP1 "Fug1, KIAA1835, SD" ENSG00000100401 "Ran GTPase activating protein 1" P46060 22 41244779-41286187 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 156.9" "Cell type enriched" "Detected in many" 9 "Late spermatids: 3236.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004293, HPA050110, HPA062034" Supported Supported "Nuclear membrane,Vesicles,Cytosol,Flagellar centriole" Yes Yes 150000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 67: Testis - Mixed function" "Cluster 24: Neurons - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 64 "Nuclear membrane" "Vesicles, Cytosol, Flagellar centriole" "CAB004293: , HPA050110: , HPA062034: " "unprognostic (6.05e-2)" "unprognostic (8.20e-2)" "unprognostic (2.22e-1)" "unprognostic (1.01e-1)" "unprognostic (4.45e-2)" "unprognostic (3.98e-1)" "unprognostic (1.23e-1)" "unprognostic (1.82e-2)" "unprognostic (2.28e-1)" "unprognostic (4.14e-2)" "unprognostic (3.67e-3)" "unprognostic (7.38e-2)" "unprognostic (2.41e-2)" "potential prognostic unfavorable (1.44e-4)" "unprognostic (1.13e-2)" "unprognostic (1.27e-3)" "unprognostic (6.24e-2)" "unprognostic (9.12e-2)" "unprognostic (1.70e-3)" "unprognostic (2.03e-1)" "unprognostic (5.09e-2)" "unprognostic (8.43e-2)" "unprognostic (1.33e-1)" "unprognostic (4.28e-2)" "unprognostic (8.35e-2)" "unprognostic (5.45e-2)" "unprognostic (2.27e-1)" "unprognostic (2.34e-3)" "unprognostic (7.12e-2)" "unprognostic (7.72e-3)" "unprognostic (4.12e-1)" RANGRF "HSPC165, HSPC236, MOG1, RANGNRF" ENSG00000108961 "RAN guanine nucleotide release factor" Q9HD47 17 8288654-8290092 "Predicted intracellular proteins" "Protein transport, Transport" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Late spermatids: 2171.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057280, HPA057888" Approved Supported Nucleoplasm,Cytosol Yes No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 21: Testis - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 35: RS4;11 - Unknown function" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 12 Nucleoplasm Cytosol "HPA057280: , HPA057888: " "unprognostic (2.11e-1)" "unprognostic (4.68e-2)" "unprognostic (6.15e-3)" "unprognostic (8.47e-3)" "unprognostic (1.27e-1)" "unprognostic (2.03e-1)" "unprognostic (4.81e-2)" "unprognostic (7.38e-2)" "unprognostic (1.98e-2)" "unprognostic (2.23e-2)" "unprognostic (2.80e-2)" "unprognostic (6.63e-3)" "unprognostic (3.92e-2)" "unprognostic (2.68e-3)" "unprognostic (1.17e-3)" "unprognostic (8.18e-2)" "unprognostic (6.48e-2)" "unprognostic (1.32e-1)" "unprognostic (4.17e-1)" "unprognostic (1.46e-1)" "unprognostic (5.95e-2)" "potential prognostic favorable (1.70e-4)" "unprognostic (3.96e-1)" "unprognostic (3.73e-1)" "unprognostic (1.49e-1)" "unprognostic (1.83e-1)" "unprognostic (1.65e-1)" "unprognostic (2.07e-1)" "unprognostic (3.26e-1)" "unprognostic (3.55e-1)" "unprognostic (7.59e-3)" RAP1A "KREV-1, SMGP21" ENSG00000116473 "RAP1A, member of RAS oncogene family" P62834 1 111542218-111716691 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" Neurogenesis Hydrolase "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 655.7;Neutrophils: 1211.2" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 669.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 9: T-cells - Adaptive immunity: Regulation" 21 "unprognostic (1.04e-1)" "unprognostic (6.45e-3)" "unprognostic (2.68e-1)" "unprognostic (2.01e-1)" "unprognostic (4.58e-2)" "unprognostic (3.13e-1)" "unprognostic (1.04e-1)" "unprognostic (1.25e-2)" "unprognostic (6.11e-2)" "unprognostic (4.39e-2)" "potential prognostic favorable (8.81e-6)" "unprognostic (6.80e-2)" "unprognostic (2.60e-1)" "potential prognostic unfavorable (3.01e-6)" "unprognostic (2.38e-2)" "unprognostic (3.66e-2)" "unprognostic (1.24e-2)" "unprognostic (2.76e-1)" "unprognostic (6.65e-2)" "unprognostic (1.38e-2)" "unprognostic (1.22e-1)" "unprognostic (9.95e-2)" "unprognostic (2.82e-2)" "unprognostic (9.48e-2)" "unprognostic (2.77e-1)" "unprognostic (7.60e-2)" "unprognostic (1.17e-1)" "unprognostic (1.71e-1)" "unprognostic (6.74e-2)" "unprognostic (1.46e-1)" "unprognostic (5.65e-2)" RAP1B "DKFZp586H0723, K-REV, RAL1B" ENSG00000127314 "RAP1B, member of RAS oncogene family" P61224 12 68610855-68671901 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Megakaryocytes: 3937.7;Neutrophils: 1007.3;Platelets: 1970.3" "Cell type enhanced" "Detected in all" "leukocyte: 577.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 60000000 "Cluster 28: Neutrophils - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 55: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 47: Platelets - Hemostasis" 37 "unprognostic (6.17e-2)" "unprognostic (2.78e-1)" "unprognostic (1.78e-1)" "unprognostic (2.02e-1)" "unprognostic (6.97e-2)" "unprognostic (2.37e-2)" "unprognostic (7.96e-3)" "unprognostic (8.06e-3)" "unprognostic (4.90e-2)" "unprognostic (1.88e-1)" "potential prognostic favorable (2.15e-5)" "unprognostic (2.62e-1)" "unprognostic (1.04e-1)" "unprognostic (1.66e-3)" "unprognostic (1.04e-1)" "unprognostic (5.76e-2)" "unprognostic (2.21e-2)" "unprognostic (8.43e-2)" "unprognostic (1.73e-1)" "unprognostic (3.15e-2)" "unprognostic (8.03e-2)" "potential prognostic unfavorable (3.42e-5)" "unprognostic (1.79e-2)" "unprognostic (2.22e-1)" "unprognostic (1.04e-1)" "unprognostic (2.05e-1)" "unprognostic (1.15e-1)" "unprognostic (1.58e-2)" "unprognostic (2.68e-1)" "unprognostic (3.04e-2)" "unprognostic (9.17e-2)" RAP1GAP "KIAA0474, RAP1GA1, RAP1GAP1, RAP1GAPII" ENSG00000076864 "RAP1 GTPase activating protein" P47736 1 21596221-21669357 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 242.8;kidney: 179.1;thyroid gland: 150.3" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 78.5;Brain excitatory neurons: 92.9;Brain inhibitory neurons: 201.0;Goblet cells: 155.0;Loop of henle epithelial cells: 128.9;Oligodendrocyte progenitor cells: 76.6;Pancreatic acinar cells: 90.5;Parietal cells: 136.1;Renal collecting duct intercalated cells: 129.5;Retinal amacrine cells: 101.9;Retinal ganglion cells: 92.7" "Cell type enhanced" "Detected in all" "medium spiny neuron: 436.8" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 256.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Breast - Breast glandular cells, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "basal ganglia: 304.0" "HPA001922, CAB003851" Enhanced Supported Approved Cytosol NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 33: Neurons - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 35: Neurons - Synaptic function & neurogenesis" 7 Cytosol "CAB003851: , HPA001922: " "unprognostic (4.96e-2)" "unprognostic (6.19e-2)" "unprognostic (1.58e-1)" "unprognostic (2.06e-1)" "unprognostic (1.58e-2)" "unprognostic (8.38e-2)" "unprognostic (3.26e-2)" "unprognostic (2.13e-1)" "unprognostic (8.12e-2)" "unprognostic (2.16e-1)" "potential prognostic favorable (7.52e-6)" "unprognostic (6.83e-3)" "unprognostic (4.36e-1)" "potential prognostic unfavorable (1.09e-5)" "unprognostic (2.48e-2)" "unprognostic (1.64e-2)" "unprognostic (4.75e-2)" "unprognostic (3.85e-3)" "unprognostic (2.22e-1)" "unprognostic (2.18e-1)" "unprognostic (1.09e-1)" "unprognostic (2.50e-2)" "unprognostic (3.01e-2)" "unprognostic (4.92e-2)" "unprognostic (3.88e-1)" "unprognostic (4.35e-3)" "unprognostic (2.59e-2)" "unprognostic (1.28e-1)" "unprognostic (3.21e-3)" "potential prognostic unfavorable (7.91e-4)" "unprognostic (1.28e-1)" RAP1GAP2 "GARNL4, KIAA1039" ENSG00000132359 "RAP1 GTPase activating protein 2" Q684P5 17 2755705-3037741 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 26.2;pancreas: 36.5" "Cell type enhanced" "Detected in many" "Neuroendocrine cells: 430.6;Neutrophil progenitors: 412.5;Neutrophils: 915.5;Pancreatic islet cells: 385.9;Retinal ganglion cells: 633.5;Thymocytes: 446.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal medulla cells, Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Minor Salivary Gland - Minor salivary glandular cells, Spleen - Neutrophils_2, Stomach - Parietal cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022148, HPA022896" Approved Approved "Nuclear membrane,Cytosol,Perinuclear theca,Flagellar centriole,Principal piece" NA NA 20000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 8: Pancreas - Proteolysis" "Cluster 53: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 1 "Nuclear membrane, Cytosol" "Perinuclear theca, Flagellar centriole, Principal piece" "HPA022148: , HPA022896: " "unprognostic (6.09e-2)" "unprognostic (1.07e-3)" "unprognostic (1.03e-1)" "unprognostic (2.05e-2)" "unprognostic (1.27e-1)" "unprognostic (9.06e-2)" "unprognostic (2.21e-1)" "unprognostic (1.43e-1)" "unprognostic (4.88e-2)" "unprognostic (1.98e-1)" "unprognostic (1.09e-3)" "unprognostic (1.09e-2)" "unprognostic (3.22e-2)" "unprognostic (3.31e-2)" "unprognostic (5.14e-2)" "unprognostic (3.36e-1)" "unprognostic (4.95e-3)" "unprognostic (6.40e-3)" "unprognostic (6.11e-2)" "unprognostic (5.03e-1)" "unprognostic (1.45e-1)" "unprognostic (2.40e-2)" "unprognostic (1.76e-1)" "unprognostic (2.38e-3)" "unprognostic (5.40e-2)" "unprognostic (7.12e-2)" "unprognostic (8.22e-2)" "unprognostic (2.83e-2)" "unprognostic (7.46e-2)" "unprognostic (1.52e-1)" RAP1GDS1 SmgGDS ENSG00000138698 "Rap1 GTPase-GDP dissociation stimulator 1" P52306 4 98261384-98443858 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Cancer-related genes, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 480.3;Rod photoreceptor cells: 503.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019060, HPA048820" Approved Supported Cytosol NA NA 92000 "Cluster 13: Non-specific - Mitochondria" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 33 Cytosol "HPA019060: , HPA048820: " "unprognostic (1.70e-1)" "unprognostic (1.13e-2)" "potential prognostic unfavorable (7.91e-4)" "unprognostic (1.14e-1)" "unprognostic (1.95e-2)" "unprognostic (4.11e-2)" "unprognostic (4.99e-2)" "unprognostic (1.44e-1)" "unprognostic (1.80e-1)" "unprognostic (2.51e-1)" "potential prognostic favorable (1.05e-7)" "unprognostic (1.65e-2)" "unprognostic (6.91e-2)" "potential prognostic unfavorable (3.86e-4)" "unprognostic (2.47e-1)" "unprognostic (2.44e-2)" "unprognostic (2.58e-2)" "unprognostic (2.94e-2)" "unprognostic (2.37e-2)" "unprognostic (4.07e-2)" "unprognostic (4.74e-2)" "unprognostic (1.96e-1)" "unprognostic (4.03e-2)" "unprognostic (2.19e-1)" "unprognostic (3.33e-2)" "unprognostic (2.78e-1)" "unprognostic (2.63e-1)" "unprognostic (1.86e-1)" "unprognostic (1.41e-1)" "unprognostic (1.37e-1)" "unprognostic (1.96e-1)" RAP2A "K-REV, RAP2" ENSG00000125249 "RAP2A, member of RAS oncogene family" P10114 13 97434169-97469128 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 123.1;Microglia: 124.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB018552 Uncertain NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 53: Neurons - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 15 "CAB018552: " "unprognostic (1.88e-1)" "unprognostic (2.54e-1)" "unprognostic (1.97e-1)" "unprognostic (3.97e-2)" "unprognostic (3.93e-1)" "unprognostic (2.07e-2)" "unprognostic (3.39e-2)" "potential prognostic favorable (6.06e-4)" "unprognostic (3.58e-2)" "unprognostic (6.12e-2)" "potential prognostic favorable (1.94e-7)" "unprognostic (2.41e-3)" "unprognostic (5.96e-2)" "potential prognostic unfavorable (1.35e-4)" "unprognostic (5.44e-3)" "unprognostic (1.57e-1)" "unprognostic (1.23e-2)" "unprognostic (1.67e-3)" "unprognostic (6.54e-3)" "unprognostic (3.70e-1)" "unprognostic (1.32e-2)" "unprognostic (1.19e-1)" "unprognostic (1.59e-2)" "unprognostic (4.71e-3)" "unprognostic (1.47e-1)" "unprognostic (1.41e-1)" "unprognostic (4.17e-2)" "unprognostic (6.67e-2)" "unprognostic (2.13e-1)" "unprognostic (7.44e-2)" "unprognostic (7.94e-2)" RAP2B ENSG00000181467 "RAP2B, member of RAS oncogene family" P61225 3 153162226-153170627 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Epididymal basal cells: 634.3;Esophageal apical cells: 381.5;Ocular epithelial cells: 587.4;Platelets: 810.8;Urothelial cells: 397.9" "Cell type enhanced" "Detected in all" "hippocampal CA4: 82.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Macrophages, Spleen - Macrophages, Stomach - Gastric mucous cells, Thyroid gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 180000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 29: Forebrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 7 "unprognostic (2.60e-1)" "unprognostic (8.89e-2)" "unprognostic (3.76e-1)" "unprognostic (9.95e-2)" "unprognostic (9.02e-2)" "unprognostic (1.82e-2)" "unprognostic (1.04e-1)" "potential prognostic unfavorable (7.11e-4)" "unprognostic (4.66e-2)" "unprognostic (7.00e-2)" "unprognostic (8.52e-3)" "unprognostic (2.01e-1)" "unprognostic (1.75e-1)" "potential prognostic unfavorable (1.24e-4)" "unprognostic (2.59e-1)" "unprognostic (8.01e-2)" "potential prognostic unfavorable (1.79e-4)" "unprognostic (1.21e-1)" "unprognostic (1.57e-1)" "unprognostic (3.84e-2)" "unprognostic (2.80e-1)" "unprognostic (7.74e-3)" "unprognostic (1.99e-2)" "unprognostic (1.19e-1)" "unprognostic (7.08e-2)" "unprognostic (1.12e-2)" "unprognostic (4.37e-2)" "unprognostic (8.06e-2)" "unprognostic (2.62e-1)" "unprognostic (1.09e-1)" "unprognostic (2.07e-1)" RAP2C DKFZp313B211 ENSG00000123728 "RAP2C, member of RAS oncogene family" Q9Y3L5 X 132203024-132219480 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 86.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 180.4;Neutrophils: 202.5;Syncytiotrophoblasts: 85.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Ribosome" "Cluster 36: Non-specific - mRNA processing" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 11 "unprognostic (1.83e-2)" "unprognostic (3.83e-2)" "unprognostic (4.83e-2)" "unprognostic (6.01e-3)" "unprognostic (8.04e-2)" "unprognostic (2.06e-3)" "unprognostic (3.40e-2)" "unprognostic (6.44e-2)" "unprognostic (1.95e-2)" "unprognostic (1.42e-3)" "unprognostic (7.56e-2)" "unprognostic (4.25e-2)" "unprognostic (3.43e-2)" "unprognostic (1.73e-1)" "unprognostic (2.68e-2)" "unprognostic (1.08e-2)" "unprognostic (7.04e-3)" "unprognostic (3.97e-1)" "unprognostic (2.15e-1)" "unprognostic (7.60e-2)" "unprognostic (6.86e-2)" "unprognostic (1.96e-2)" "unprognostic (2.07e-2)" "unprognostic (1.78e-2)" "unprognostic (1.75e-1)" "unprognostic (1.08e-1)" "unprognostic (1.78e-1)" "unprognostic (4.70e-1)" "unprognostic (2.57e-1)" "unprognostic (2.66e-2)" "unprognostic (1.48e-1)" RAPGEF1 "C3G, GRF2" ENSG00000107263 "Rap guanine nucleotide exchange factor 1" Q13905 9 131576770-131740076 "Plasma proteins, Predicted intracellular proteins" Neurogenesis "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 522.4;cDC: 623.3;Macrophages: 543.8;Microglia: 521.9;monocytes: 663.0;Neutrophils: 712.9;Pancreatic acinar cells: 493.7;Plasma cells: 1122.2;Retinal horizontal cells: 687.2" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 699.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 4.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006426, HPA075984" Enhanced Supported Vesicles NA NA "Cluster 32: Basophils - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 44: Plasma cells - Antibody production & secretion" 18 Vesicles "HPA006426: , HPA075984: " "unprognostic (1.32e-1)" "unprognostic (1.38e-1)" "unprognostic (1.43e-2)" "unprognostic (1.25e-1)" "unprognostic (1.04e-1)" "unprognostic (9.71e-2)" "unprognostic (7.26e-2)" "unprognostic (1.77e-1)" "unprognostic (2.77e-1)" "unprognostic (3.47e-1)" "potential prognostic favorable (7.09e-7)" "unprognostic (2.33e-3)" "unprognostic (4.45e-2)" "unprognostic (5.60e-2)" "unprognostic (4.55e-2)" "unprognostic (1.20e-1)" "unprognostic (1.27e-1)" "unprognostic (4.33e-2)" "unprognostic (2.71e-2)" "unprognostic (7.33e-3)" "unprognostic (1.43e-2)" "unprognostic (9.18e-2)" "unprognostic (8.03e-2)" "unprognostic (4.18e-1)" "unprognostic (3.13e-2)" "unprognostic (5.53e-3)" "unprognostic (2.84e-1)" "unprognostic (1.17e-1)" "unprognostic (1.71e-1)" "unprognostic (5.07e-2)" "unprognostic (3.11e-1)" RAPGEF2 "DKFZP586O1422, KIAA0313, PDZ-GEF1, PDZGEF1, RA-GEF" ENSG00000109756 "Rap guanine nucleotide exchange factor 2" Q9Y4G8 4 159103013-159360174 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein, GTPase activation, Guanine-nucleotide releasing factor" Epilepsy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 943.8;Neutrophils: 953.7" "Cell type enhanced" "Detected in all" "endothelial cell: 1728.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.3" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Spleen - Endothelial cells, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068798 Supported "Plasma membrane,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 104: Brain endothelial cells - Blood brain barrier" 20 "Plasma membrane, Cytosol" "HPA068798: " "unprognostic (3.80e-2)" "unprognostic (2.27e-1)" "unprognostic (7.51e-2)" "unprognostic (1.20e-2)" "unprognostic (1.12e-1)" "unprognostic (1.44e-1)" "unprognostic (1.28e-1)" "unprognostic (7.01e-3)" "unprognostic (2.84e-2)" "unprognostic (7.66e-3)" "validated prognostic favorable (4.54e-8)" "validated prognostic favorable (2.48e-6)" "unprognostic (1.85e-1)" "unprognostic (2.70e-2)" "potential prognostic favorable (6.68e-5)" "unprognostic (6.42e-2)" "unprognostic (1.15e-1)" "unprognostic (9.04e-3)" "unprognostic (1.56e-1)" "unprognostic (5.30e-3)" "unprognostic (1.25e-1)" "unprognostic (9.57e-3)" "unprognostic (4.70e-2)" "unprognostic (2.10e-1)" "unprognostic (2.09e-2)" "potential prognostic favorable (6.31e-4)" "unprognostic (2.13e-1)" "unprognostic (3.50e-1)" "unprognostic (2.12e-1)" "unprognostic (3.87e-2)" "unprognostic (3.30e-1)" RAPGEF3 "bcm910, cAMP-GEFI, EPAC" ENSG00000079337 "Rap guanine nucleotide exchange factor 3" O95398 12 47734363-47771040 "Predicted intracellular proteins" Angiogenesis "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 134.1;Loop of henle epithelial cells: 102.3;Oligodendrocytes: 53.3;Papillary tip epithelial cells: 48.9;Podocytes: 190.0;Proximal tubule cells: 103.1;Renal collecting duct intercalated cells: 62.0;Renal collecting duct principal cells: 114.2;Renal connecting tubule cells: 91.9;Vascular endothelial cells: 85.6" "Cell type enhanced" "Detected in many" "astrocyte: 133.9;endothelial cell: 60.7;oligodendrocyte: 59.1" "Cancer enhanced" "Detected in all" "Thyroid Carcinoma (TCGA): 31.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Uterine cancer: 44.3" "Adipose visceral - Endothelial cells, Colon - Endothelial cells, Liver - Vascular endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004386, HPA040365, HPA043518" Approved Uncertain "Endoplasmic reticulum,Cytosol" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 11: White matter - Signal transduction" "Cluster 15: Kidney cancer - Membrane components" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 2 Cytosol "Endoplasmic reticulum" "CAB004386: , HPA040365: , HPA043518: " "unprognostic (7.06e-3)" "unprognostic (2.31e-1)" "unprognostic (2.78e-3)" "unprognostic (1.39e-1)" "unprognostic (8.62e-2)" "unprognostic (9.08e-2)" "unprognostic (1.38e-1)" "unprognostic (4.22e-2)" "unprognostic (1.29e-2)" "potential prognostic favorable (4.91e-5)" "validated prognostic favorable (7.52e-6)" "validated prognostic favorable (9.80e-5)" "unprognostic (2.34e-3)" "validated prognostic favorable (6.28e-4)" "validated prognostic favorable (2.16e-5)" "unprognostic (1.78e-2)" "unprognostic (3.31e-2)" "unprognostic (9.00e-3)" "unprognostic (2.00e-2)" "unprognostic (1.86e-2)" "unprognostic (1.63e-1)" "unprognostic (9.96e-2)" "unprognostic (4.59e-3)" "unprognostic (6.81e-2)" "unprognostic (7.94e-2)" "unprognostic (3.39e-2)" "unprognostic (1.79e-2)" "unprognostic (1.20e-2)" "unprognostic (5.19e-2)" "unprognostic (6.69e-2)" "unprognostic (3.43e-2)" RAPGEF4 "cAMP-GEFII, CGEF2" ENSG00000091428 "Rap guanine nucleotide exchange factor 4" Q8WZA2 2 172735274-173052893 "Predicted intracellular proteins" Exocytosis "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 272.2" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 683.9;Brain excitatory neurons: 450.3;Brain inhibitory neurons: 458.4;Cone photoreceptor cells: 679.0;Oligodendrocyte progenitor cells: 485.3;Other brain neurons: 256.0;Retinal amacrine cells: 210.0;Retinal ganglion cells: 301.3;Retinal pigment epithelial cells: 673.5;Somatotrophs: 223.6;Vascular endothelial cells: 431.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 10.0" "Colon - Endothelial cells, Liver - Hepatocytes, Lung - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Keratinocyte (granular), Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004388, HPA028968" Approved Approved "Plasma membrane,Focal adhesion sites,Basal body,Cytosol,Mid piece" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 9 "Focal adhesion sites" "Plasma membrane, Basal body, Cytosol, Mid piece" "CAB004388: , HPA028968: " "unprognostic (1.21e-1)" "unprognostic (1.49e-1)" "unprognostic (2.38e-1)" "unprognostic (5.65e-3)" "unprognostic (2.29e-1)" "unprognostic (8.91e-2)" "unprognostic (5.55e-2)" "potential prognostic favorable (3.87e-4)" "unprognostic (2.76e-2)" "unprognostic (1.22e-1)" "validated prognostic favorable (1.75e-9)" "validated prognostic favorable (7.16e-4)" "potential prognostic unfavorable (4.86e-6)" "unprognostic (3.61e-2)" "unprognostic (3.97e-3)" "unprognostic (8.16e-2)" "unprognostic (6.90e-2)" "unprognostic (2.44e-2)" "unprognostic (2.69e-2)" "unprognostic (4.47e-1)" "unprognostic (1.27e-1)" "potential prognostic favorable (2.53e-4)" "unprognostic (6.32e-2)" "unprognostic (8.34e-2)" "unprognostic (2.06e-1)" "unprognostic (1.84e-2)" "unprognostic (5.20e-2)" "unprognostic (1.28e-2)" "unprognostic (3.69e-2)" "unprognostic (5.85e-2)" "unprognostic (8.76e-2)" RAPGEF5 "GFR, KIAA0277, MR-GEF" ENSG00000136237 "Rap guanine nucleotide exchange factor 5" Q92565 7 22118236-22357154 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 158.3;parathyroid gland: 364.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 391.9;Brain excitatory neurons: 426.1;Brain inhibitory neurons: 378.7;Esophageal apical cells: 341.8;Lymphatic endothelial cells: 419.2;Oligodendrocytes: 889.4;Pituitary stem cells: 356.9;Sertoli cells: 322.3;Vascular endothelial cells: 455.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Spleen - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057821, HPA076772" Uncertain Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 69: Parathyroid gland - Mixed function" "Cluster 30: White matter - Myelination" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 3 Nucleoplasm "Nuclear bodies" "HPA057821: , HPA076772: " "unprognostic (1.77e-2)" "unprognostic (5.26e-2)" "unprognostic (1.66e-1)" "unprognostic (4.63e-2)" "unprognostic (3.55e-2)" "unprognostic (1.54e-1)" "unprognostic (1.40e-1)" "unprognostic (2.24e-1)" "unprognostic (1.40e-3)" "unprognostic (1.20e-1)" "validated prognostic favorable (6.00e-10)" "validated prognostic favorable (1.30e-5)" "unprognostic (1.31e-1)" "unprognostic (8.80e-2)" "unprognostic (3.54e-1)" "unprognostic (1.73e-2)" "unprognostic (4.51e-2)" "unprognostic (1.83e-1)" "unprognostic (3.40e-1)" "unprognostic (2.24e-1)" "unprognostic (2.08e-1)" "unprognostic (2.13e-1)" "unprognostic (1.47e-1)" "unprognostic (1.55e-1)" "unprognostic (1.32e-1)" "unprognostic (1.01e-1)" "unprognostic (1.13e-1)" "unprognostic (1.25e-2)" "unprognostic (4.51e-2)" "unprognostic (1.20e-1)" "unprognostic (1.95e-2)" RAPGEF6 "PDZ-GEF2, PDZGEF2, RA-GEF-2" ENSG00000158987 "Rap guanine nucleotide exchange factor 6" Q8TEU7 5 131423921-131635231 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 114.2;Bergmann glia: 146.5;Brain excitatory neurons: 297.3;Brain inhibitory neurons: 270.6;Choroid plexus epithelial cells: 169.2;Ependymal cells: 123.7;Microglia: 527.9;Oligodendrocyte progenitor cells: 198.1;Oligodendrocytes: 483.9;Other brain neurons: 215.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037982, HPA037983" Approved Approved Centrosome,Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 61: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 22: Non-specific - Basic cellular functions" 18 Cytosol Centrosome "HPA037982: , HPA037983: " "unprognostic (1.51e-2)" "unprognostic (1.37e-1)" "unprognostic (1.06e-1)" "unprognostic (7.07e-2)" "unprognostic (7.61e-2)" "unprognostic (2.24e-1)" "unprognostic (1.85e-1)" "unprognostic (7.62e-2)" "unprognostic (8.19e-2)" "unprognostic (8.27e-3)" "potential prognostic favorable (1.34e-6)" "unprognostic (1.72e-3)" "unprognostic (1.03e-1)" "unprognostic (1.08e-1)" "unprognostic (1.33e-1)" "unprognostic (2.05e-1)" "unprognostic (3.11e-1)" "unprognostic (2.33e-2)" "unprognostic (9.85e-2)" "unprognostic (1.44e-2)" "unprognostic (2.04e-2)" "unprognostic (1.29e-1)" "unprognostic (5.34e-3)" "unprognostic (1.93e-2)" "unprognostic (3.06e-3)" "unprognostic (2.13e-2)" "unprognostic (2.73e-1)" "unprognostic (1.10e-1)" "unprognostic (2.80e-1)" "unprognostic (1.15e-1)" "unprognostic (2.18e-1)" RAPGEFL1 Link-GEFII ENSG00000108352 "Rap guanine nucleotide exchange factor like 1" Q9UHV5 17 40177010-40195656 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 194.7;skin 1: 231.9;vagina: 109.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 112.4;Colonocytes: 113.1;Enterocytes: 114.4;Esophageal apical cells: 249.4;Esophageal basal cells: 121.0;Esophageal suprabasal cells: 254.4;Ocular epithelial cells: 148.7;Papillary tip epithelial cells: 104.0;Prostatic hillock cells: 238.5;Respiratory basal cells: 121.7;Respiratory secretory cells: 94.8;Suprabasal keratinocytes: 197.5;Urothelial cells: 104.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 53.8" "Kidney - Endothelial cells, Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Urothelial cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022895 Approved "Nucleoplasm,Microtubules,Cytokinetic bridge" Yes No "Cluster 58: Skin - Keratinization" "Cluster 51: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 85: Squamous epithelial cells - Keratinization" "Nucleoplasm, Microtubules" "Cytokinetic bridge" "HPA022895: " "unprognostic (3.72e-3)" "unprognostic (1.40e-2)" "unprognostic (1.80e-1)" "unprognostic (9.91e-3)" "unprognostic (6.23e-2)" "unprognostic (1.09e-2)" "unprognostic (1.42e-1)" "unprognostic (6.69e-3)" "unprognostic (4.10e-2)" "unprognostic (7.76e-2)" "potential prognostic unfavorable (5.88e-9)" "unprognostic (6.12e-3)" "potential prognostic unfavorable (7.53e-4)" "unprognostic (7.71e-2)" "unprognostic (6.87e-2)" "unprognostic (1.92e-1)" "unprognostic (6.24e-2)" "unprognostic (7.15e-2)" "unprognostic (5.58e-2)" "unprognostic (4.04e-1)" "unprognostic (1.89e-2)" "unprognostic (6.67e-3)" "unprognostic (2.17e-1)" "potential prognostic unfavorable (4.42e-5)" "unprognostic (1.51e-2)" "unprognostic (1.89e-1)" "unprognostic (1.20e-1)" "unprognostic (1.75e-2)" "unprognostic (1.44e-1)" "unprognostic (6.83e-2)" "unprognostic (2.29e-1)" RAPH1 "ALS2CR18, ALS2CR9, KIAA1681" ENSG00000173166 "Ras association (RalGDS/AF-6) and pleckstrin homology domains 1" Q70E73 2 203394345-203535335 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 57.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 391.9;Epicardial cells: 384.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Breast - Breast glandular cells, Liver - Hepatocytes, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016744, HPA020027" Approved Approved "Nuclear bodies,Plasma membrane,Cytosol" NA NA 34000000 "Cluster 33: Non-specific - ATP binding" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 14: Neurons - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 9 "Nuclear bodies, Plasma membrane" Cytosol "HPA016744: , HPA020027: " "unprognostic (5.48e-2)" "unprognostic (7.51e-2)" "unprognostic (2.67e-1)" "unprognostic (4.36e-2)" "unprognostic (1.36e-1)" "unprognostic (7.83e-2)" "unprognostic (2.12e-1)" "unprognostic (2.33e-1)" "unprognostic (1.37e-1)" "unprognostic (3.84e-2)" "validated prognostic favorable (1.59e-4)" "validated prognostic favorable (1.85e-4)" "unprognostic (2.60e-2)" "unprognostic (2.08e-2)" "unprognostic (8.90e-2)" "unprognostic (4.42e-2)" "unprognostic (2.17e-2)" "unprognostic (2.19e-2)" "unprognostic (4.49e-1)" "unprognostic (7.50e-2)" "unprognostic (2.20e-1)" "potential prognostic unfavorable (4.45e-5)" "unprognostic (3.49e-2)" "unprognostic (7.76e-2)" "unprognostic (5.56e-2)" "unprognostic (1.64e-1)" "unprognostic (2.87e-1)" "unprognostic (1.03e-1)" "unprognostic (1.69e-1)" "unprognostic (8.18e-3)" "unprognostic (2.35e-2)" RAPSN "CMS1D, CMS1E, RNF205" ENSG00000165917 "Receptor associated protein of the synapse" Q13702 11 47437764-47449143 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 23 "skeletal muscle: 83.3;tongue: 31.0" "Cell type enhanced" "Detected in many" "Epididymal efferent duct absorptive cells: 7.7;Late spermatids: 21.9;Myonuclei: 44.8;Myosatellite cells: 66.6;Neutrophils: 8.7;Thymic myoid cells: 16.3" "Cell type enhanced" "Detected in single" "choroid plexus epithelial cell: 2.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 36 "Sarcoma: 37.3" "Colon - Enteric glia cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in some" HPA039475 Approved Approved "Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 12: Non-specific - Vasculature" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 3 "Plasma membrane, Centrosome, Cytosol" "HPA039475: " "unprognostic (6.08e-2)" "unprognostic (1.42e-1)" "unprognostic (5.28e-2)" RARA "NR1B1, RAR, RAR-alpha, RARalpha" ENSG00000131759 "Retinoic acid receptor alpha" P10276 17 40309180-40357643 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 170.1;Late spermatids: 303.7;monocytes: 112.6;Neutrophils: 281.0" "Cell type enhanced" "Detected in many" "leukocyte: 42.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 52.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058282, HPA071548" Supported "Nucleoplasm,Nucleoli,Actin filaments,Cytosol" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 27: Breast cancer - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 104 Nucleoplasm "Nucleoli, Actin filaments, Cytosol" "HPA058282: , HPA071548: " "unprognostic (1.53e-2)" "unprognostic (1.93e-1)" "unprognostic (8.07e-2)" "unprognostic (2.99e-3)" "unprognostic (2.55e-1)" "unprognostic (8.95e-2)" "unprognostic (9.26e-3)" "unprognostic (2.45e-1)" "unprognostic (1.13e-2)" "unprognostic (9.12e-2)" "potential prognostic favorable (9.68e-4)" "unprognostic (1.09e-2)" "unprognostic (2.88e-1)" "unprognostic (2.62e-1)" "unprognostic (1.43e-1)" "unprognostic (1.27e-1)" "unprognostic (4.02e-2)" "unprognostic (6.10e-2)" "unprognostic (1.22e-1)" "unprognostic (1.85e-2)" "unprognostic (1.07e-1)" "unprognostic (1.28e-1)" "unprognostic (1.27e-1)" "unprognostic (2.21e-1)" "unprognostic (7.92e-2)" "unprognostic (4.01e-2)" "unprognostic (1.87e-1)" "unprognostic (6.51e-3)" "unprognostic (3.65e-2)" "unprognostic (6.68e-2)" "unprognostic (3.15e-3)" RARB "HAP, NR1B2, RAR-beta, RARbeta, RRB2" ENSG00000077092 "Retinoic acid receptor beta" P10826 3 24687887-25597932 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, Disease variant, FDA approved drug targets, Microphthalmia, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 292.7;Cone photoreceptor cells: 302.2;Conjunctival goblet cells: 338.8;Müller glia: 680.2;Pituicytes/FSCs: 291.2;Prostatic glandular cells: 273.4;Renal collecting duct intercalated cells: 268.1;Salivary duct cells: 285.9;Thymic myoid cells: 224.3" "Cell type enhanced" "Detected in all" "eccentric medium spiny neuron: 647.3;medium spiny neuron: 638.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells" "Region enriched" "Detected in all" 9 "basal ganglia: 109.3" "Low region specificity" "Detected in all" "CAB002617, HPA004174" Enhanced Enhanced Nucleoplasm NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 105: Non-specific - Mixed function" 9 Nucleoplasm "CAB002617: , HPA004174: " "unprognostic (1.18e-1)" "unprognostic (7.83e-2)" "unprognostic (1.19e-1)" "unprognostic (2.27e-2)" "unprognostic (1.28e-1)" "unprognostic (3.06e-1)" "unprognostic (1.14e-1)" "unprognostic (1.77e-1)" "unprognostic (1.78e-1)" "unprognostic (4.31e-1)" "validated prognostic favorable (2.12e-9)" "validated prognostic favorable (1.09e-4)" "unprognostic (2.17e-1)" "unprognostic (3.07e-2)" "unprognostic (1.59e-2)" "unprognostic (8.76e-2)" "unprognostic (1.48e-1)" "unprognostic (2.88e-2)" "unprognostic (2.61e-1)" "unprognostic (7.88e-2)" "unprognostic (1.59e-2)" "unprognostic (1.56e-1)" "unprognostic (2.20e-1)" "unprognostic (1.20e-1)" "unprognostic (2.32e-1)" "unprognostic (4.18e-3)" "unprognostic (1.80e-1)" "unprognostic (1.13e-2)" "unprognostic (2.14e-1)" "unprognostic (3.71e-2)" "unprognostic (3.57e-2)" RARG "NR1B3, RAR-gamma, RARC, RARgamma" ENSG00000172819 "Retinoic acid receptor gamma" P13631 12 53210567-53232980 "Cancer-related genes, FDA approved drug targets, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 137.7;skin 1: 114.7" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 393.9;Esophageal basal cells: 112.4;Esophageal suprabasal cells: 180.3;Prostatic hillock cells: 88.6;Suprabasal keratinocytes: 85.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 18.9" "Group enriched" "Detected in all" 4 "dendritic cells: 6.7;T-cells: 18.9" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053883 Supported Supported Nucleoplasm NA NA "Cluster 27: T-cells - Unknown function" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 15: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 12 Nucleoplasm "HPA053883: " "unprognostic (2.23e-2)" "unprognostic (2.32e-1)" "unprognostic (2.55e-2)" "unprognostic (2.69e-1)" "unprognostic (3.44e-1)" "unprognostic (2.96e-1)" "unprognostic (3.17e-1)" "unprognostic (4.96e-2)" "unprognostic (8.10e-2)" "unprognostic (4.99e-3)" "unprognostic (4.04e-3)" "unprognostic (2.14e-2)" "unprognostic (1.32e-1)" "unprognostic (3.96e-1)" "unprognostic (2.60e-2)" "unprognostic (1.55e-2)" "unprognostic (8.22e-2)" "unprognostic (1.79e-1)" "unprognostic (4.36e-1)" "unprognostic (1.88e-3)" "unprognostic (1.04e-1)" "unprognostic (1.25e-3)" "unprognostic (3.20e-1)" "unprognostic (2.34e-2)" "unprognostic (8.73e-2)" "unprognostic (4.06e-2)" "unprognostic (5.35e-2)" "unprognostic (3.75e-2)" "unprognostic (1.46e-2)" "unprognostic (1.78e-2)" "unprognostic (3.46e-1)" RARRES1 "LXNL, TIG1" ENSG00000118849 "Retinoic acid receptor responder 1" P49788 3 158696892-158732489 "Predicted intracellular proteins" "Protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 233.7;fallopian tube: 173.0;salivary gland: 172.7" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 3279.6;Endometrial secretory cells: 5678.0;Lacrimal acinar cells: 768.1;Mesothelial cells: 1281.0;Prostatic club cells: 3433.9;Salivary basal cells: 994.8;Salivary ionocytes: 1392.2;Submucosal glandular cells: 1610.9" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Bladder Urothelial Carcinoma (TCGA): 189.0" "Region enriched" "Detected in all" 4 "choroid plexus: 28.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "Bile duct cancer: 62.0;breast cancer: 207.5;pancreatic cancer: 67.3" "Lung - Fibroblasts_2, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003892 Uncertain Approved "Endoplasmic reticulum,Golgi apparatus" "Intracellular and membrane" "Enzyme inhibitor" NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 1 "Golgi apparatus" "Endoplasmic reticulum" "HPA003892: " "unprognostic (6.87e-2)" "unprognostic (1.06e-2)" "unprognostic (1.00e-1)" "unprognostic (1.06e-1)" "unprognostic (3.28e-1)" "unprognostic (1.40e-2)" "validated prognostic unfavorable (1.15e-4)" "validated prognostic unfavorable (1.52e-4)" "unprognostic (3.65e-2)" "unprognostic (1.55e-1)" "potential prognostic unfavorable (7.50e-7)" "unprognostic (2.71e-3)" "unprognostic (6.57e-2)" "unprognostic (7.90e-2)" "unprognostic (1.39e-1)" "unprognostic (1.25e-1)" "unprognostic (7.83e-2)" "unprognostic (2.59e-1)" "unprognostic (5.11e-2)" "unprognostic (4.65e-3)" "unprognostic (3.71e-2)" "unprognostic (6.89e-2)" "unprognostic (4.60e-2)" "unprognostic (1.52e-1)" "unprognostic (4.59e-2)" "unprognostic (1.27e-1)" "unprognostic (2.80e-2)" "unprognostic (4.51e-1)" "unprognostic (3.37e-1)" "unprognostic (3.43e-2)" "unprognostic (1.86e-2)" RARRES2 "HP10433, TIG2" ENSG00000106538 "Retinoic acid receptor responder 2" Q99969 7 150338317-150341662 "Plasma proteins, Predicted secreted proteins" "Chemotaxis, Differentiation, Inflammatory response" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 2645.8;liver: 2145.2" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 723.7;Endometrial secretory cells: 564.9;Enteric stem cells: 470.6;Enteric transient amplifying cells: 496.7;Epididymal clear cells: 834.9;Fibroblasts: 494.7;Hepatocytes: 2988.4;Müller glia: 509.8;Oocytes: 538.8;Ovarian stromal cells: 640.9;Pancreatic acinar cells: 869.4;Respiratory ionocytes: 889.0;Salivary ionocytes: 1360.3" "Group enriched" "Detected in many" 4 "choroid plexus epithelial cell: 123.7;ependymal cell: 98.1;fibroblast: 84.9;oligodendrocyte precursor cell: 68.5;pericyte: 75.4;vascular associated smooth muscle cell: 46.9" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 1782.2" "Region enriched" "Detected in all" 8 "choroid plexus: 596.7" "Immune cell enriched" "Detected in single" 8 "plasmacytoid DC: 5.4" "Lineage enriched" "Detected in single" 8 "dendritic cells: 5.4" "Cancer enhanced" "Detected in many" "Kidney cancer: 575.4" "Kidney - Fibroblasts, Lung - Fibroblasts_1, Prostate - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" Other NA NA 75000000 160000000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 36: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 108: Fibroblasts - ECM organization" 2 "potential prognostic favorable (5.11e-4)" "unprognostic (2.53e-1)" "unprognostic (3.73e-1)" "unprognostic (9.83e-2)" "unprognostic (7.77e-2)" "unprognostic (1.57e-1)" "validated prognostic unfavorable (4.66e-4)" "validated prognostic unfavorable (3.64e-6)" "unprognostic (6.15e-2)" "unprognostic (8.11e-2)" "potential prognostic unfavorable (3.06e-4)" "unprognostic (8.56e-2)" "unprognostic (5.47e-2)" "unprognostic (1.57e-2)" "unprognostic (9.25e-3)" "unprognostic (1.98e-2)" "unprognostic (1.76e-2)" "unprognostic (1.35e-2)" "unprognostic (3.76e-2)" "unprognostic (2.00e-2)" "unprognostic (3.81e-3)" "unprognostic (3.10e-3)" "unprognostic (1.14e-1)" "unprognostic (1.81e-1)" "unprognostic (7.08e-2)" "potential prognostic favorable (1.96e-4)" "unprognostic (2.47e-1)" "unprognostic (3.97e-2)" "unprognostic (5.19e-2)" "unprognostic (3.08e-2)" "unprognostic (1.46e-1)" RARS1 "DALRD1, RARS" ENSG00000113643 "Arginyl-tRNA synthetase 1" P54136 5 168486451-168519301 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003979, HPA004130" Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA 140000 "Cluster 33: Non-specific - ATP binding" "Cluster 76: Non-specific - Metabolism" "Cluster 31: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 36 Cytosol "Nucleoplasm, Nucleoli" "HPA003979: , HPA004130: " "unprognostic (9.10e-3)" "unprognostic (8.61e-3)" "unprognostic (1.87e-3)" "unprognostic (8.02e-2)" "unprognostic (4.81e-3)" "unprognostic (1.54e-1)" "unprognostic (1.04e-1)" "potential prognostic unfavorable (3.70e-5)" "potential prognostic unfavorable (7.87e-4)" "potential prognostic favorable (7.99e-6)" "unprognostic (3.12e-2)" "unprognostic (3.97e-2)" "potential prognostic unfavorable (4.48e-7)" "unprognostic (2.13e-3)" "unprognostic (2.08e-2)" "unprognostic (1.87e-1)" "unprognostic (2.10e-1)" "unprognostic (2.29e-1)" "unprognostic (2.10e-3)" "unprognostic (3.12e-3)" "unprognostic (5.87e-2)" "unprognostic (8.09e-2)" "unprognostic (3.61e-3)" "unprognostic (2.02e-2)" "unprognostic (1.14e-1)" "unprognostic (1.91e-1)" "unprognostic (1.26e-1)" "unprognostic (4.22e-2)" "unprognostic (1.11e-1)" RARS2 "DALRD2, dJ382I10.6, MGC14993, MGC23778, PRO1992, RARSL" ENSG00000146282 "Arginyl-tRNA synthetase 2, mitochondrial" Q5T160 6 87513459-87590028 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Neurodegeneration, Pontocerebellar hypoplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039987, HPA042645" Uncertain Approved Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 76: Non-specific - Metabolism" "Cluster 6: Non-specific - Immune response" "Cluster 28: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" 20 Mitochondria "HPA039987: , HPA042645: " "unprognostic (4.13e-1)" "unprognostic (6.57e-3)" "potential prognostic unfavorable (3.84e-4)" "unprognostic (4.14e-2)" "unprognostic (2.64e-1)" "unprognostic (1.46e-2)" "unprognostic (2.44e-1)" "unprognostic (1.59e-1)" "unprognostic (8.19e-2)" "unprognostic (6.21e-3)" "unprognostic (1.94e-3)" "unprognostic (1.75e-3)" "unprognostic (1.70e-1)" "unprognostic (2.48e-2)" "unprognostic (4.13e-2)" "unprognostic (3.35e-1)" "unprognostic (3.58e-1)" "unprognostic (7.87e-3)" "unprognostic (1.36e-1)" "unprognostic (2.04e-2)" "unprognostic (1.34e-1)" "unprognostic (3.20e-1)" "potential prognostic unfavorable (5.92e-4)" "unprognostic (1.70e-1)" "unprognostic (1.13e-3)" "unprognostic (3.34e-1)" "unprognostic (2.08e-2)" "unprognostic (1.13e-1)" "unprognostic (7.95e-3)" "unprognostic (1.41e-1)" "unprognostic (3.90e-1)" RASA1 "CM-AVM, GAP, p120, p120GAP, p120RASGAP, RASA" ENSG00000145715 "RAS p21 protein activator 1" P20936 5 87267883-87391931 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "GTPase activation" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 91.1" "Cell type enhanced" "Detected in all" "Adipocytes: 663.2;Cardiomyocytes: 955.6;Cytotrophoblasts: 637.9;Epicardial cells: 1407.7;Syncytiotrophoblasts: 1493.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007789, HPA036393, HPA064556" Enhanced Approved "Vesicles,Basal body,Cytosol" NA NA 17000 "Cluster 33: Non-specific - ATP binding" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 31: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 40 "Vesicles, Basal body" Cytosol "CAB007789: , HPA036393: , HPA064556: " "unprognostic (2.35e-1)" "unprognostic (2.03e-1)" "unprognostic (2.65e-1)" "unprognostic (8.77e-2)" "unprognostic (8.21e-2)" "unprognostic (2.25e-1)" "unprognostic (1.57e-1)" "unprognostic (9.87e-2)" "unprognostic (6.11e-2)" "unprognostic (1.01e-1)" "potential prognostic favorable (6.85e-4)" "unprognostic (1.12e-1)" "unprognostic (3.97e-1)" "unprognostic (3.26e-2)" "unprognostic (1.43e-1)" "unprognostic (2.89e-2)" "unprognostic (1.26e-2)" "unprognostic (1.67e-2)" "unprognostic (4.57e-2)" "unprognostic (5.30e-2)" "potential prognostic unfavorable (5.73e-4)" "potential prognostic unfavorable (6.58e-4)" "unprognostic (4.05e-3)" "unprognostic (2.24e-1)" "unprognostic (1.90e-2)" "unprognostic (2.05e-1)" "unprognostic (1.39e-1)" "unprognostic (1.44e-2)" "unprognostic (4.55e-2)" "unprognostic (2.54e-1)" "unprognostic (2.82e-2)" RASA2 GAP1M ENSG00000155903 "RAS p21 protein activator 2" Q15283 3 141487027-141615344 "Predicted intracellular proteins, RAS pathway related proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Innate lymphoid cells: 642.3;Neutrophil progenitors: 680.9;Neutrophils: 1229.0;NK-cells: 696.4;Urothelial cells: 643.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035374, HPA035375" Approved Approved Vesicles NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 53: Neurons - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 2 Vesicles "HPA035374: , HPA035375: " "unprognostic (7.95e-3)" "unprognostic (2.12e-1)" "unprognostic (2.95e-2)" "unprognostic (1.06e-2)" "unprognostic (1.51e-1)" "unprognostic (1.15e-1)" "unprognostic (2.13e-1)" "unprognostic (3.82e-1)" "potential prognostic favorable (7.21e-4)" "unprognostic (1.29e-3)" "unprognostic (1.05e-1)" "unprognostic (5.84e-2)" "unprognostic (6.01e-2)" "unprognostic (1.17e-2)" "unprognostic (3.16e-1)" "unprognostic (1.74e-1)" "potential prognostic unfavorable (8.58e-4)" "unprognostic (2.66e-1)" "unprognostic (3.92e-3)" "unprognostic (2.34e-1)" "unprognostic (7.35e-2)" "unprognostic (3.70e-2)" "unprognostic (1.32e-3)" "unprognostic (4.08e-2)" "unprognostic (1.80e-2)" "unprognostic (1.84e-1)" "unprognostic (1.76e-1)" "unprognostic (1.32e-1)" "unprognostic (4.47e-1)" "unprognostic (1.31e-1)" "unprognostic (1.18e-2)" RASA3 "GAP1IP4BP, GAPIII" ENSG00000185989 "RAS p21 protein activator 3" Q14644 13 113977783-114132623 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 38.4;Bergmann glia: 49.4;Brain excitatory neurons: 29.3;Ependymal cells: 84.9;Megakaryocytes: 24.7;Microglia: 152.6;NK-cells: 69.3;Oligodendrocyte progenitor cells: 27.5;Oligodendrocytes: 28.2;Other brain neurons: 32.0;Platelets: 31.0;T-cells: 27.0" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 192.2;leukocyte: 305.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046759 Uncertain NA NA 820000 "Cluster 1: T-cells - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 11: White matter - Signal transduction" "Cluster 19: Non-specific - Unknown function" "Cluster 102: Non-specific - Mixed function" 3 "HPA046759: " "unprognostic (2.04e-3)" "unprognostic (1.96e-1)" "unprognostic (2.24e-2)" "unprognostic (2.57e-3)" "unprognostic (3.32e-2)" "unprognostic (4.74e-3)" "unprognostic (1.78e-2)" "unprognostic (6.78e-2)" "unprognostic (1.74e-1)" "unprognostic (3.70e-1)" "unprognostic (3.44e-2)" "unprognostic (1.98e-1)" "unprognostic (9.85e-3)" "unprognostic (2.37e-3)" "unprognostic (4.35e-2)" "unprognostic (2.64e-2)" "unprognostic (4.35e-2)" "unprognostic (1.39e-2)" "unprognostic (8.96e-3)" "unprognostic (4.26e-2)" "unprognostic (2.73e-2)" "unprognostic (8.98e-3)" "unprognostic (1.96e-1)" "unprognostic (2.29e-1)" "unprognostic (2.23e-1)" "unprognostic (2.42e-2)" "unprognostic (2.84e-1)" "unprognostic (5.81e-2)" "unprognostic (3.32e-3)" "unprognostic (6.19e-2)" "unprognostic (3.45e-1)" RASA4 "CAPRI, GAPL, KIAA0538" ENSG00000105808 "RAS p21 protein activator 4" O43374 7 102579646-102616756 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "skeletal muscle: 223.0;tongue: 76.1" "Cell type enhanced" "Detected in some" "Astrocytes: 12.9;Bergmann glia: 17.9;Brain inhibitory neurons: 2.6;Ependymal cells: 5.6;Microglia: 12.1;Oligodendrocyte progenitor cells: 4.7;Other brain neurons: 4.0" "Cell type enhanced" "Detected in many" "astrocyte: 18.6;central nervous system macrophage: 14.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA043010 Uncertain Approved "Vesicles,Cell Junctions" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 28: Astrocytes - Homeostasis & neuron support" Vesicles "Cell Junctions" "HPA043010: " "unprognostic (1.82e-3)" "unprognostic (1.29e-1)" "unprognostic (1.64e-1)" "unprognostic (1.07e-2)" "unprognostic (6.97e-3)" "unprognostic (1.53e-1)" "unprognostic (7.56e-2)" "unprognostic (9.54e-3)" "unprognostic (2.29e-1)" "unprognostic (2.43e-1)" "potential prognostic favorable (2.18e-4)" "unprognostic (3.74e-1)" "unprognostic (1.48e-2)" "unprognostic (3.54e-2)" "unprognostic (2.65e-1)" "unprognostic (8.14e-2)" "unprognostic (3.88e-1)" "unprognostic (1.56e-2)" "unprognostic (4.33e-2)" "unprognostic (6.67e-2)" "unprognostic (2.77e-2)" "unprognostic (2.55e-3)" "unprognostic (6.63e-2)" "unprognostic (1.59e-1)" "unprognostic (5.10e-3)" "unprognostic (3.14e-1)" "unprognostic (1.73e-3)" "potential prognostic unfavorable (7.74e-4)" "unprognostic (6.15e-2)" "unprognostic (1.57e-1)" "unprognostic (3.70e-2)" RASA4B ENSG00000170667 "RAS p21 protein activator 4B" C9J798 7 102479976-102517777 "Predicted intracellular proteins, RAS pathway related proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skeletal muscle: 93.2" "Cell type enriched" "Detected in many" 7 "Myonuclei: 160.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.2;intermediate monocyte: 1.6;myeloid DC: 3.2;plasmacytoid DC: 1.9" "Group enriched" "Detected in many" 6 "dendritic cells: 3.2;monocytes: 2.2" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Endothelial cells" HPA043010 Uncertain Approved "Vesicles,Cell Junctions" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" Vesicles "Cell Junctions" "HPA043010: " "unprognostic (7.45e-2)" "unprognostic (8.31e-2)" "unprognostic (3.40e-3)" "unprognostic (4.75e-2)" "unprognostic (3.89e-2)" "unprognostic (6.54e-2)" "unprognostic (5.78e-2)" "unprognostic (9.31e-2)" "unprognostic (4.84e-2)" "unprognostic (3.23e-1)" "unprognostic (7.23e-2)" "unprognostic (1.50e-1)" "unprognostic (9.05e-2)" "unprognostic (1.21e-2)" "unprognostic (8.87e-2)" "unprognostic (3.38e-2)" "unprognostic (1.29e-2)" "unprognostic (1.60e-2)" "potential prognostic favorable (3.09e-4)" "unprognostic (1.72e-1)" "unprognostic (2.99e-1)" "unprognostic (3.03e-2)" "unprognostic (1.26e-1)" "unprognostic (9.37e-2)" "potential prognostic unfavorable (8.15e-4)" "unprognostic (5.92e-2)" "unprognostic (1.40e-2)" "unprognostic (5.15e-2)" RASAL1 RASAL ENSG00000111344 "RAS protein activator like 1" O95294 12 113098819-113136239 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" Differentiation "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 56.1;salivary gland: 26.2" "Cell type enhanced" "Detected in many" "Corticotrophs: 50.3;Esophageal apical cells: 206.8;Esophageal suprabasal cells: 45.6;Foveolar cells: 55.5;Gonadotrophs: 47.1;Lacrimal acinar cells: 49.8;Loop of henle epithelial cells: 40.6;Oligodendrocytes: 50.0;Papillary tip epithelial cells: 49.1;Renal collecting duct principal cells: 175.8;Renal connecting tubule cells: 58.6;Salivary acinar cells: 60.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "lymphoma: 12.8" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells (progenitors), Liver - Cholangiocytes, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Corticotropes, Prostate - Urothelial cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "amygdala: 18.4;cerebral cortex: 18.8;hippocampal formation: 28.0" HPA041650 Enhanced Approved "Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 69: Parathyroid gland - Mixed function" "Cluster 34: Non-specific - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" "Plasma membrane, Cytosol" "Cell Junctions" "HPA041650: " "unprognostic (5.05e-3)" "unprognostic (1.55e-1)" "unprognostic (5.51e-2)" "unprognostic (4.32e-3)" "unprognostic (1.97e-1)" "unprognostic (7.97e-2)" "unprognostic (1.72e-2)" "unprognostic (1.79e-1)" "unprognostic (1.30e-2)" "potential prognostic favorable (5.27e-4)" "unprognostic (2.48e-1)" "unprognostic (1.44e-1)" "unprognostic (2.81e-1)" "unprognostic (3.01e-2)" "unprognostic (1.57e-1)" "unprognostic (1.39e-2)" "unprognostic (4.99e-2)" "potential prognostic unfavorable (9.30e-4)" "unprognostic (1.16e-1)" "unprognostic (1.20e-2)" "unprognostic (2.12e-2)" "unprognostic (2.40e-1)" "unprognostic (1.06e-2)" "unprognostic (1.88e-1)" "unprognostic (7.26e-3)" "unprognostic (2.78e-1)" "unprognostic (7.99e-2)" RASAL2 nGAP ENSG00000075391 "RAS protein activator like 2" Q9UJF2 1 178094104-178484147 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 1058.9;Rod photoreceptor cells: 1144.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Liver - Vascular endothelial cells, Lung - Endothelial cells, Spleen - Endothelial cells, Stomach - Endothelial cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018805, HPA020453" Enhanced Approved "Plasma membrane,Focal adhesion sites" NA Yes "Cluster 42: Retina - Visual perception" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 72: Neuronal - Signal transduction" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 35 "Plasma membrane, Focal adhesion sites" "HPA018805: , HPA020453: " "unprognostic (1.76e-1)" "unprognostic (1.89e-2)" "unprognostic (1.46e-1)" "unprognostic (1.32e-3)" "unprognostic (6.28e-2)" "unprognostic (2.90e-2)" "unprognostic (1.70e-1)" "potential prognostic favorable (5.61e-4)" "unprognostic (8.31e-2)" "unprognostic (1.44e-2)" "potential prognostic favorable (8.87e-6)" "unprognostic (1.19e-3)" "unprognostic (9.29e-2)" "unprognostic (1.06e-2)" "unprognostic (2.93e-1)" "unprognostic (3.09e-3)" "potential prognostic unfavorable (9.38e-6)" "unprognostic (3.49e-2)" "unprognostic (3.15e-2)" "unprognostic (7.61e-2)" "unprognostic (1.03e-2)" "unprognostic (6.95e-3)" "potential prognostic unfavorable (1.16e-4)" "unprognostic (1.39e-1)" "unprognostic (7.30e-2)" "unprognostic (9.32e-3)" "unprognostic (2.94e-1)" "unprognostic (1.80e-1)" "unprognostic (2.35e-1)" "unprognostic (1.28e-1)" "unprognostic (1.52e-1)" RASAL3 FLJ21438 ENSG00000105122 "RAS protein activator like 3" Q86YV0 19 15451624-15464544 "Predicted intracellular proteins, RAS pathway related proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 22.2;intestine: 19.0;lung: 10.6;lymphoid tissue: 39.2" "Cell type enhanced" "Detected in some" "B-cells: 45.9;Hematopoietic stem cells: 25.2;Innate lymphoid cells: 54.8;Mast cells: 29.2;Microglia: 60.6;Neutrophil progenitors: 64.6;Neutrophils: 42.1;NK-cells: 98.1;Plasma cells: 23.9;T-cells: 92.5;Thymocytes: 33.9" "Group enriched" "Detected in some" 115 "central nervous system macrophage: 70.8;leukocyte: 97.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 17 "Leukemia: 25.6;lymphoma: 20.9;Myeloma: 29.9" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Minor Salivary Gland - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Stomach - T-cells, Thyroid gland - T-cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA043417 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 15 "Nucleoplasm, Plasma membrane" "HPA043417: " "unprognostic (9.30e-3)" "unprognostic (2.01e-2)" "unprognostic (1.01e-3)" "unprognostic (2.68e-3)" "unprognostic (8.80e-2)" "unprognostic (6.17e-2)" "unprognostic (1.79e-1)" "unprognostic (6.95e-2)" "potential prognostic favorable (7.56e-4)" "unprognostic (5.72e-2)" "unprognostic (6.64e-2)" "unprognostic (1.44e-1)" "unprognostic (1.43e-1)" "unprognostic (7.63e-2)" "unprognostic (4.31e-3)" "unprognostic (1.01e-2)" "unprognostic (5.68e-2)" "unprognostic (1.47e-1)" "unprognostic (2.19e-1)" "unprognostic (3.91e-1)" "unprognostic (5.46e-2)" "unprognostic (2.59e-2)" "unprognostic (1.55e-1)" "unprognostic (2.23e-1)" "unprognostic (1.27e-1)" "unprognostic (4.08e-2)" "unprognostic (8.99e-3)" "unprognostic (3.66e-1)" "unprognostic (2.48e-2)" "unprognostic (2.71e-2)" "unprognostic (1.26e-1)" RASD1 "AGS1, DEXRAS1" ENSG00000108551 "Ras related dexamethasone induced 1" Q9Y272 17 17494437-17496395 "Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pituitary gland: 351.7" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 251.8;Endometrial glandular cells: 455.5;Endometrial luminal cells: 436.1;Epididymal principal cells: 243.6;Goblet cells: 258.4;Müller glia: 391.3;Myosatellite cells: 253.0;Pericytes: 251.2;Peritubular myoid cells: 416.6" "Cell type enhanced" "Detected in all" "astrocyte: 82.2;Bergmann glia: 88.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 46 "plasmacytoid DC: 160.3" "Lineage enriched" "Detected in many" 46 "dendritic cells: 160.3" "Low cancer specificity" "Detected in many" "Liver - Neutrophils, Pituitary gland - Corticotropes" "Group enriched" "Detected in all" 5 "basal ganglia: 75.6;hippocampal formation: 54.9;thalamus: 53.2" "Low region specificity" "Detected in all" HPA047896 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 70: Non-specific - Protein processing" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 6: Leukemia - Signal transduction" "Cluster 51: Secretory epithelial cells - Mixed function" 26 Nucleoplasm "Plasma membrane" "HPA047896: " "unprognostic (2.55e-1)" "unprognostic (2.83e-1)" "unprognostic (2.66e-1)" "unprognostic (3.80e-2)" "unprognostic (6.07e-2)" "unprognostic (6.26e-2)" "unprognostic (6.13e-2)" "potential prognostic favorable (4.70e-4)" "unprognostic (1.14e-1)" "potential prognostic favorable (4.56e-4)" "unprognostic (7.63e-3)" "potential prognostic favorable (9.12e-6)" "unprognostic (1.46e-1)" "unprognostic (1.22e-1)" "unprognostic (5.96e-3)" "unprognostic (5.28e-3)" "unprognostic (2.80e-1)" "unprognostic (1.43e-1)" "unprognostic (3.96e-2)" "unprognostic (1.93e-1)" "unprognostic (1.86e-1)" "unprognostic (1.30e-3)" "unprognostic (6.51e-2)" "unprognostic (2.06e-1)" "unprognostic (6.65e-2)" "unprognostic (1.46e-1)" "unprognostic (9.39e-2)" "potential prognostic unfavorable (8.56e-4)" "unprognostic (1.69e-1)" "unprognostic (5.51e-2)" "unprognostic (9.27e-2)" RASD2 "MGC:4834, Rhes, TEM2" ENSG00000100302 "RASD family member 2" Q96D21 22 35540831-35553999 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 184.3" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 31.9;Brain inhibitory neurons: 29.2;Breast secretory cells: 7.5;Epididymal clear cells: 12.2;Epididymal principal cells: 20.7;Fibroblasts: 8.6;Goblet cells: 15.4;Pericytes: 30.3;Retinal amacrine cells: 9.0;Smooth muscle cells: 8.9" "Cell type enhanced" "Detected in many" "medium spiny neuron: 68.1;midbrain-derived inhibitory: 50.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "basal ganglia: 465.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 8.8" "Adrenal gland - Adrenal medulla cells, Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Skeletal myocytes" "Region enriched" "Detected in all" 8 "basal ganglia: 589.8" "Region enriched" "Detected in all" 9 "basal ganglia: 559.2" HPA005839 Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 17: Non-specific - RNA processing" 5 "Plasma membrane, Cytosol" "HPA005839: " "unprognostic (1.82e-2)" "unprognostic (1.12e-2)" "unprognostic (4.10e-2)" "unprognostic (1.64e-1)" "unprognostic (2.59e-1)" "unprognostic (3.34e-1)" "unprognostic (1.06e-1)" "unprognostic (3.00e-1)" "unprognostic (2.90e-3)" "unprognostic (6.99e-2)" "unprognostic (2.07e-1)" "unprognostic (7.30e-3)" "unprognostic (3.95e-3)" "unprognostic (6.76e-2)" "unprognostic (3.68e-2)" "unprognostic (2.35e-1)" "unprognostic (2.22e-2)" "unprognostic (5.47e-2)" "unprognostic (3.65e-2)" "unprognostic (1.27e-2)" "unprognostic (2.49e-2)" "unprognostic (1.85e-1)" "unprognostic (8.61e-2)" "unprognostic (1.05e-1)" "unprognostic (1.64e-2)" "unprognostic (1.53e-1)" "unprognostic (6.49e-2)" "unprognostic (8.26e-2)" RASEF "FLJ31614, RAB45, TSG" ENSG00000165105 "RAS and EF-hand domain containing" Q8IZ41 9 82979590-83063177 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 38.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 424.4;Breast hormone-responsive cells: 289.2;Conjunctival goblet cells: 285.4;Endometrial glandular cells: 539.5;Foveolar cells: 1189.5;Goblet cells: 413.0;Pancreatic acinar cells: 441.3;Prostatic glandular cells: 549.0;Urothelial cells: 456.9" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 137.4;fibroblast: 50.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Breast - Breast glandular cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Pituitary gland - Corticotropes, Prostate - Prostate glandular cells, Skin - Outer root sheath cells, Stomach - Gastric mucous cells, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA021431, HPA078596" Approved Approved Microtubules NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 60: Stomach - Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 68: Foveolar cells - Mucosal defense" 1 Microtubules "HPA021431: , HPA078596: " "unprognostic (1.61e-1)" "unprognostic (6.05e-2)" "unprognostic (4.50e-1)" "unprognostic (2.60e-3)" "unprognostic (1.42e-3)" "unprognostic (1.44e-1)" "unprognostic (2.08e-1)" "unprognostic (1.36e-2)" "unprognostic (3.37e-1)" "potential prognostic unfavorable (1.65e-5)" "validated prognostic favorable (3.38e-5)" "validated prognostic favorable (9.58e-5)" "unprognostic (6.37e-2)" "unprognostic (5.38e-3)" "unprognostic (1.60e-1)" "unprognostic (2.39e-1)" "unprognostic (3.79e-1)" "unprognostic (4.42e-1)" "unprognostic (2.49e-1)" "unprognostic (1.04e-1)" "unprognostic (3.83e-1)" "unprognostic (1.87e-3)" "unprognostic (1.50e-1)" "unprognostic (2.43e-1)" "unprognostic (4.62e-2)" "unprognostic (1.07e-1)" "unprognostic (1.08e-1)" "unprognostic (4.94e-1)" "unprognostic (1.80e-1)" "unprognostic (2.27e-1)" "unprognostic (2.90e-1)" RASGEF1A "CG4853, FLJ37817" ENSG00000198915 "RasGEF domain family member 1A" Q8N9B8 10 43194535-43267065 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 13.8;brain: 19.2" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 21.3;Brain excitatory neurons: 29.2;Brain inhibitory neurons: 30.6;Neutrophils: 24.2;Oocytes: 13.8;Other brain neurons: 26.6;Pituitary stem cells: 20.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 12.4" "Pituitary gland - Undifferentiated cells (Pituitary gland), Prostate - Fibroblasts, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035593 Enhanced Approved "Golgi apparatus" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" "Golgi apparatus" "HPA035593: " "unprognostic (1.62e-1)" "unprognostic (1.09e-2)" "unprognostic (2.43e-1)" "unprognostic (7.32e-2)" "unprognostic (8.73e-2)" "unprognostic (1.49e-1)" "unprognostic (7.37e-2)" "unprognostic (2.37e-1)" "unprognostic (3.51e-1)" "unprognostic (3.74e-3)" "unprognostic (1.37e-1)" "unprognostic (1.44e-1)" "unprognostic (5.58e-2)" "unprognostic (5.00e-2)" "unprognostic (3.02e-2)" "unprognostic (4.26e-2)" "unprognostic (1.56e-1)" "unprognostic (4.69e-2)" "unprognostic (2.41e-1)" "unprognostic (1.60e-1)" "unprognostic (3.54e-1)" "unprognostic (1.34e-1)" "unprognostic (9.26e-2)" "unprognostic (1.18e-1)" "unprognostic (3.57e-2)" "unprognostic (1.14e-1)" "unprognostic (3.30e-1)" "unprognostic (4.47e-2)" "unprognostic (1.09e-1)" RASGEF1B "FLJ31695, GPIG4" ENSG00000138670 "RasGEF domain family member 1B" Q0VAM2 4 81426393-82044244 "Predicted intracellular proteins, Predicted membrane proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 39.0" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 1489.4;Hepatocytes: 1070.7;Kupffer cells: 1407.2" "Group enriched" "Detected in all" 4 "cerebellar inhibitory: 446.0;committed oligodendrocyte precursor: 1111.9;lower rhombic lip: 1106.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "intermediate monocyte: 11.9;memory B-cell: 9.7;naive B-cell: 12.4;non-classical monocyte: 20.7;plasmacytoid DC: 27.9" "Group enriched" "Detected in all" 5 "B-cells: 12.4;dendritic cells: 27.9;monocytes: 20.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044574 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 58: Skin - Keratinization" "Cluster 49: Hindbrain - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" Nucleoplasm Vesicles "HPA044574: " "unprognostic (1.05e-1)" "unprognostic (2.80e-1)" "unprognostic (3.10e-1)" "unprognostic (1.91e-2)" "unprognostic (6.46e-2)" "unprognostic (1.10e-2)" "unprognostic (2.44e-1)" "unprognostic (2.79e-2)" "potential prognostic favorable (9.14e-4)" "unprognostic (1.97e-1)" "potential prognostic favorable (1.70e-7)" "unprognostic (5.04e-3)" "potential prognostic favorable (8.92e-7)" "unprognostic (9.87e-2)" "potential prognostic favorable (7.96e-4)" "unprognostic (1.46e-1)" "unprognostic (2.90e-2)" "unprognostic (1.11e-1)" "unprognostic (2.96e-1)" "unprognostic (1.98e-1)" "unprognostic (3.24e-1)" "unprognostic (2.88e-2)" "unprognostic (8.45e-2)" "unprognostic (5.10e-2)" "unprognostic (2.09e-1)" "unprognostic (1.83e-1)" "unprognostic (3.23e-1)" "unprognostic (5.06e-2)" "unprognostic (5.21e-2)" "unprognostic (2.51e-2)" "unprognostic (5.06e-2)" RASGEF1C FLJ35841 ENSG00000146090 "RasGEF domain family member 1C" Q8N431 5 180100795-180209211 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 6 "brain: 31.9" "Cell type enriched" "Detected in many" 7 "Microglia: 688.5" "Cell type enriched" "Detected in many" 4 "central nervous system macrophage: 843.1" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 4.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Stomach - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028242 Uncertain Approved Mitochondria NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 1: Neuronal - Visual perception" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" Mitochondria "HPA028242: " "unprognostic (2.68e-2)" "unprognostic (1.16e-3)" "unprognostic (2.04e-1)" "unprognostic (2.83e-1)" "unprognostic (4.13e-2)" RASGRF1 "CDC25, CDC25L, GNRP, GRF1, GRF55, H-GRF55, PP13187" ENSG00000058335 "Ras protein specific guanine nucleotide releasing factor 1" Q13972 15 78959906-79090780 "Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 51.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 151.7;Brain excitatory neurons: 127.1;Brain inhibitory neurons: 85.3;Epididymal efferent duct absorptive cells: 34.3;Oligodendrocytes: 125.8;Other brain neurons: 51.7;Pancreatic islet cells: 40.8;Retinal amacrine cells: 239.7;Retinal ganglion cells: 38.6;Retinal horizontal cells: 48.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Pancreas - Beta cells, Pituitary gland - Gonadotropes, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010413, HPA041965" Approved Approved "Golgi apparatus" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 37: Neurons - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 80: Oligodendrocytes - Myelination" 2 "Golgi apparatus" "CAB010413: , HPA041965: " "unprognostic (1.26e-2)" "unprognostic (2.24e-1)" "unprognostic (3.31e-2)" "unprognostic (1.92e-1)" "unprognostic (3.06e-2)" "unprognostic (1.51e-3)" "unprognostic (1.38e-1)" "potential prognostic unfavorable (4.79e-4)" "unprognostic (1.14e-1)" "unprognostic (4.80e-2)" "unprognostic (1.91e-2)" "unprognostic (5.47e-3)" "unprognostic (6.20e-2)" "unprognostic (1.30e-2)" RASGRF2 "GRF2, Ras-GRF2" ENSG00000113319 "Ras protein specific guanine nucleotide releasing factor 2" O14827 5 80960363-81230162 "Predicted intracellular proteins, RAS pathway related proteins" "Calmodulin-binding, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 21.2" "Cell type enhanced" "Detected in many" "Adipocytes: 184.7;Brain inhibitory neurons: 210.5;Choroid plexus epithelial cells: 844.7;Cone photoreceptor cells: 633.5;Extravillous trophoblasts: 372.3;Oligodendrocytes: 423.9;Oocytes: 193.4;Retinal pigment epithelial cells: 204.6;Rod photoreceptor cells: 577.6;Vascular endothelial cells: 302.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 1.9;MAIT T-cell: 5.2;memory CD4 T-cell: 2.6;memory CD8 T-cell: 1.5;naive CD4 T-cell: 4.2;naive CD8 T-cell: 3.0" "Lineage enriched" "Detected in single" 52 "T-cells: 5.2" "Cancer enhanced" "Detected in many" "testis cancer: 14.9" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Breast - Endothelial cells, Heart muscle - Endothelial cells, Minor Salivary Gland - Endothelial cells, Pancreas - Endothelial cells, Prostate - Fibroblasts, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA018679 Uncertain Supported "Endoplasmic reticulum" NA NA "Cluster 27: T-cells - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" "Endoplasmic reticulum" "HPA018679: " "unprognostic (8.58e-2)" "unprognostic (1.28e-1)" "unprognostic (1.37e-1)" "unprognostic (1.00e-1)" "unprognostic (9.27e-2)" "unprognostic (1.80e-1)" "unprognostic (2.67e-2)" "unprognostic (2.53e-1)" "unprognostic (1.20e-2)" "validated prognostic favorable (2.26e-8)" "validated prognostic favorable (2.03e-4)" "potential prognostic unfavorable (1.36e-4)" "unprognostic (1.03e-2)" "potential prognostic favorable (1.05e-4)" "unprognostic (3.92e-2)" "unprognostic (2.48e-1)" "unprognostic (4.84e-2)" "unprognostic (1.43e-1)" "unprognostic (2.23e-2)" "unprognostic (1.88e-2)" "unprognostic (8.41e-2)" "unprognostic (1.94e-1)" "unprognostic (1.04e-1)" "unprognostic (4.65e-2)" "unprognostic (1.55e-2)" "unprognostic (1.11e-3)" "unprognostic (5.40e-2)" "unprognostic (1.98e-2)" RASGRP1 "CalDAG-GEFII, RASGRP" ENSG00000172575 "RAS guanyl releasing protein 1" O95267 15 38488103-38565575 "Disease related genes, Human disease related genes, Predicted intracellular proteins, RAS pathway related proteins" Differentiation "Guanine-nucleotide releasing factor" "Disease variant, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.3;lymphoid tissue: 35.6;retina: 16.6" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 100.9;Esophageal apical cells: 92.9;Müller glia: 262.2;NK-cells: 153.8;Renal collecting duct principal cells: 112.0;Renal connecting tubule cells: 95.6;T-cells: 204.6" "Cell type enhanced" "Detected in all" "eccentric medium spiny neuron: 296.2;leukocyte: 303.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 4.8" "Lineage enriched" "Detected in single" 8 "T-cells: 4.8" "Group enriched" "Detected in many" 4 "Leukemia: 9.4;lymphoma: 17.1;Myeloma: 6.6" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Colon - T-cells, Liver - T-cells, Prostate - T-cells, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039389 Supported "Plasma membrane,Cytosol" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 9: T-cells - Adaptive immunity: Regulation" 3 Cytosol "Plasma membrane" "HPA039389: " "unprognostic (2.48e-1)" "unprognostic (7.85e-3)" "unprognostic (2.81e-1)" "unprognostic (2.13e-2)" "unprognostic (4.66e-2)" "unprognostic (4.35e-1)" "unprognostic (3.66e-2)" "unprognostic (1.98e-1)" "unprognostic (3.21e-3)" "unprognostic (4.36e-2)" "validated prognostic favorable (1.36e-4)" "validated prognostic favorable (1.54e-4)" "unprognostic (1.29e-2)" "unprognostic (2.40e-2)" "unprognostic (1.22e-1)" "unprognostic (4.44e-2)" "unprognostic (4.80e-1)" "unprognostic (1.70e-1)" "unprognostic (1.08e-1)" "unprognostic (1.21e-1)" "unprognostic (2.73e-1)" "unprognostic (1.61e-1)" "unprognostic (4.33e-2)" "unprognostic (4.60e-2)" "unprognostic (3.75e-2)" "unprognostic (3.11e-1)" "unprognostic (3.49e-1)" "unprognostic (1.11e-1)" RASGRP2 CALDAG-GEFI ENSG00000068831 "RAS guanyl releasing protein 2" Q7LDG7 11 64726911-64745456 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 139.0;lymphoid tissue: 137.9" "Group enriched" "Detected in many" 6 "Megakaryocytes: 636.7;Platelets: 1342.3" "Cell type enhanced" "Detected in all" "pericyte: 98.7;vascular associated smooth muscle cell: 79.8" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 25.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 9 "Leukemia: 109.2;lymphoma: 43.8" "Adrenal gland - Fibroblasts, Prostate - Smooth muscle cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015635, HPA015667" Approved Supported "Plasma membrane" NA NA 700000 "Cluster 29: Non-specific - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 33: Neurons - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 47: Platelets - Hemostasis" "Plasma membrane" "HPA015635: , HPA015667: " "unprognostic (5.99e-2)" "unprognostic (9.43e-2)" "unprognostic (2.31e-2)" "unprognostic (1.57e-2)" "unprognostic (1.05e-1)" "unprognostic (2.00e-1)" "unprognostic (9.30e-3)" "unprognostic (6.79e-3)" "unprognostic (1.91e-3)" "unprognostic (1.65e-2)" "unprognostic (2.65e-2)" "unprognostic (5.02e-2)" "unprognostic (1.17e-1)" "unprognostic (2.80e-2)" "potential prognostic favorable (7.55e-5)" "potential prognostic favorable (2.57e-4)" "unprognostic (3.81e-2)" "unprognostic (9.56e-3)" "unprognostic (3.06e-1)" "unprognostic (2.88e-1)" "unprognostic (8.57e-2)" "unprognostic (7.79e-2)" "unprognostic (2.14e-2)" "unprognostic (1.41e-2)" "unprognostic (2.36e-1)" "unprognostic (5.58e-2)" "unprognostic (3.45e-1)" "unprognostic (1.49e-2)" "unprognostic (6.72e-2)" "unprognostic (1.61e-2)" "unprognostic (2.12e-1)" RASGRP3 "CalDAG-GEFIII, GRP3, KIAA0846" ENSG00000152689 "RAS guanyl releasing protein 3" Q8IV61 2 33436324-33564750 "Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 47.4;skeletal muscle: 39.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 245.1;Endometrial glandular cells: 191.7;Lymphatic endothelial cells: 292.6;Myonuclei: 457.1;Oligodendrocytes: 216.8;Pancreatic acinar cells: 864.3;Pancreatic duct cells: 160.2;Plasma cells: 284.2;Urothelial cells: 420.0" "Cell type enhanced" "Detected in all" "endothelial cell: 236.8;oligodendrocyte: 343.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 17 "basophil: 13.4;memory B-cell: 12.3;naive B-cell: 15.1" "Group enriched" "Detected in many" 18 "B-cells: 15.1;granulocytes: 13.4" "Group enriched" "Detected in many" 6 "lymphoma: 53.5;Myeloma: 43.2" "Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Heart muscle - Cardiomyocytes, Kidney - Endothelial cells, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039136 Approved "Golgi apparatus,Cytosol" NA NA "Cluster 32: Basophils - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 51: Secretory epithelial cells - Mixed function" 5 Cytosol "Golgi apparatus" "HPA039136: " "unprognostic (2.00e-2)" "unprognostic (3.67e-1)" "unprognostic (5.21e-3)" "unprognostic (3.05e-1)" "unprognostic (2.43e-2)" "unprognostic (2.77e-1)" "unprognostic (7.00e-2)" "unprognostic (2.41e-1)" "potential prognostic favorable (6.07e-4)" "unprognostic (1.63e-1)" "validated prognostic favorable (4.91e-9)" "validated prognostic favorable (2.37e-6)" "unprognostic (6.53e-2)" "unprognostic (9.51e-2)" "unprognostic (2.24e-3)" "unprognostic (4.09e-2)" "unprognostic (2.96e-1)" "unprognostic (4.92e-2)" "unprognostic (6.20e-3)" "unprognostic (2.91e-2)" "unprognostic (2.11e-1)" "unprognostic (3.27e-1)" "unprognostic (3.69e-3)" "unprognostic (1.75e-1)" "unprognostic (6.37e-2)" "unprognostic (4.27e-2)" "unprognostic (4.12e-2)" "unprognostic (5.60e-3)" "unprognostic (9.76e-2)" "unprognostic (1.13e-1)" "unprognostic (1.54e-2)" RASGRP4 ENSG00000171777 "RAS guanyl releasing protein 4" Q8TDF6 19 38409051-38426305 "Predicted intracellular proteins, RAS pathway related proteins" Differentiation "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 19.6;lymphoid tissue: 9.4" "Cell type enriched" "Detected in some" 4 "Neutrophils: 218.8" "Group enriched" "Detected in some" 10 "central nervous system macrophage: 17.1;leukocyte: 5.3" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 3.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 39.5" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in some" 6 "Leukemia: 7.5" "Adipose subcutaneous - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Kidney - Macrophages, Lung - Neutrophils_2, Minor Salivary Gland - Macrophages, Pituitary gland - Macrophages, Spleen - Neutrophils_2, Thyroid gland - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA041929 Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 6: Non-specific - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA041929: " "unprognostic (2.79e-2)" "unprognostic (1.80e-1)" "unprognostic (9.14e-2)" "unprognostic (4.31e-1)" "potential prognostic favorable (1.86e-4)" "unprognostic (1.14e-1)" "unprognostic (1.27e-1)" "unprognostic (4.41e-2)" "unprognostic (1.39e-1)" "unprognostic (3.96e-2)" "unprognostic (2.20e-1)" "unprognostic (2.23e-1)" RASIP1 "FLJ20401, RAIN" ENSG00000105538 "Ras interacting protein 1" Q5U651 19 48720585-48740610 "Predicted intracellular proteins" Angiogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Lymphatic endothelial cells: 114.7;Parietal cells: 33.6;Vascular endothelial cells: 144.8" "Cell type enriched" "Detected in many" 8 "endothelial cell: 104.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 19.4" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Pituitary gland - Endothelial cells, Prostate - Endothelial cells, Thyroid gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077251 Approved NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 1 "HPA077251: " "unprognostic (5.12e-2)" "unprognostic (2.44e-1)" "unprognostic (1.77e-1)" "unprognostic (1.81e-1)" "unprognostic (1.21e-2)" "unprognostic (9.26e-3)" "unprognostic (6.47e-2)" "unprognostic (5.56e-2)" "potential prognostic favorable (2.23e-4)" "potential prognostic favorable (3.29e-4)" "validated prognostic favorable (1.73e-8)" "validated prognostic favorable (1.03e-4)" "unprognostic (3.91e-3)" "unprognostic (1.89e-1)" "unprognostic (1.50e-3)" "unprognostic (5.00e-1)" "unprognostic (8.01e-2)" "unprognostic (4.06e-2)" "unprognostic (1.31e-1)" "unprognostic (9.27e-2)" "unprognostic (1.33e-1)" "unprognostic (1.27e-3)" "unprognostic (4.01e-1)" "unprognostic (1.37e-1)" "unprognostic (1.11e-1)" "unprognostic (2.21e-2)" "unprognostic (3.00e-2)" "potential prognostic unfavorable (7.10e-4)" "unprognostic (2.60e-1)" "unprognostic (6.28e-2)" "unprognostic (2.16e-2)" RASL10A RRP22 ENSG00000100276 "RAS like family 10 member A" Q92737 22 29312933-29319679 "Enzymes, Predicted intracellular proteins" Hydrolase "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 38.7" "Cell type enhanced" "Detected in many" "Astrocytes: 46.5;Brain excitatory neurons: 31.0;Breast secretory cells: 39.4;Microglia: 15.0;Myosatellite cells: 22.5;Oocytes: 55.3;Somatotrophs: 14.1" "Cell type enhanced" "Detected in many" "hippocampal CA1-3: 78.3" "Group enriched" "Detected in some" 5 "Glioblastoma Multiforme (TCGA): 5.9;Testicular Germ Cell Tumor (TCGA): 5.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Breast glandular cells (progenitors), Prostate - Prostate glandular cells" "Group enriched" "Detected in many" 6 "amygdala: 33.7;basal ganglia: 16.7;cerebral cortex: 36.0;hippocampal formation: 26.3;white matter: 15.3" "Group enriched" "Detected in many" 4 "cerebral cortex: 51.8;hippocampal formation: 39.8" HPA056169 Approved NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 35: Neurons - Synaptic function & neurogenesis" "HPA056169: " "unprognostic (1.01e-1)" "unprognostic (4.90e-2)" "unprognostic (1.70e-2)" "potential prognostic favorable (5.93e-4)" "unprognostic (2.12e-1)" RASL10B "RRP17, VTS58635" ENSG00000270885 "RAS like family 10 member B" Q96S79 17 35731639-35743521 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.3;skeletal muscle: 29.5" "Cell type enhanced" "Detected in some" "Breast lactating cells: 24.2;Early spermatids: 10.9;Epididymal efferent duct absorptive cells: 9.5;Fallopian secretory cells: 9.3;Hepatocytes: 10.0;Late primary spermatocytes: 12.4;Late spermatids: 57.3;Müller glia: 20.5;Retinal amacrine cells: 14.5;Retinal pigment epithelial cells: 12.8" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Glioblastoma Multiforme (TCGA): 12.1;Testicular Germ Cell Tumor (TCGA): 28.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 21.7;Neuroblastoma: 24.6" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046842, HPA057092" Enhanced Approved Vesicles NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 11: Muller glia cells - Retinal homeostasis" 26 Vesicles "HPA046842: , HPA057092: " "unprognostic (3.02e-1)" "unprognostic (1.56e-1)" "unprognostic (5.00e-1)" "unprognostic (3.71e-3)" "unprognostic (4.49e-2)" "unprognostic (1.61e-1)" "unprognostic (1.54e-1)" "unprognostic (2.80e-2)" "unprognostic (3.52e-3)" "unprognostic (4.66e-2)" "unprognostic (2.23e-2)" "unprognostic (3.14e-2)" "unprognostic (2.95e-2)" "unprognostic (2.62e-2)" "unprognostic (1.63e-1)" "unprognostic (1.92e-1)" "unprognostic (2.97e-2)" "unprognostic (2.16e-1)" "unprognostic (4.19e-2)" "unprognostic (1.30e-2)" "unprognostic (1.93e-3)" "unprognostic (8.32e-2)" "unprognostic (2.72e-1)" RASL11A ENSG00000122035 "RAS like family 11 member A" Q6T310 13 27270830-27275192 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Colonocytes: 108.1;Enterocytes: 100.7;Epicardial cells: 50.0;Goblet cells: 43.1;Pericytes: 95.9;Smooth muscle cells: 62.0;Vascular smooth muscle cells: 113.5" "Group enriched" "Detected in many" 4 "hippocampal CA4: 30.5;pericyte: 47.9;vascular associated smooth muscle cell: 33.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 1.3" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Rhabdoid: 11.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA004859, HPA053296" Supported Approved "Nuclear bodies" Yes No "Cluster 40: Monocytes - Innate immune response" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 15: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 65: Non-specific - Cell growth & division" 12 "Nuclear bodies" "HPA004859: , HPA053296: " "unprognostic (1.51e-2)" "unprognostic (1.99e-1)" "unprognostic (8.68e-3)" "unprognostic (1.31e-1)" "unprognostic (2.75e-3)" "unprognostic (1.79e-2)" "unprognostic (1.49e-1)" "unprognostic (1.62e-2)" "unprognostic (4.38e-2)" "unprognostic (5.65e-2)" "unprognostic (1.35e-1)" "unprognostic (5.81e-3)" "unprognostic (3.77e-3)" "unprognostic (6.49e-2)" "unprognostic (1.55e-1)" "potential prognostic favorable (2.24e-4)" "unprognostic (9.91e-2)" "unprognostic (1.22e-1)" "unprognostic (2.93e-1)" "unprognostic (4.15e-1)" "unprognostic (8.81e-2)" "unprognostic (3.02e-2)" "unprognostic (9.66e-3)" "unprognostic (9.47e-2)" "unprognostic (1.39e-1)" "unprognostic (2.29e-2)" "unprognostic (5.49e-2)" "unprognostic (1.58e-1)" "unprognostic (1.16e-1)" "unprognostic (1.34e-1)" RASL11B ENSG00000128045 "RAS like family 11 member B" Q9BPW5 4 52862317-52866835 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 28.0;ovary: 64.4" "Group enriched" "Detected in some" 4 "Podocytes: 53.2;Renal collecting duct principal cells: 13.6" "Cell type enhanced" "Detected in many" "fibroblast: 12.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 12.5" "Pituitary gland - Undifferentiated cells (Pituitary gland), Skin - Inner root sheath cells, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057803 Uncertain Approved "Nuclear bodies" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 1 "Nuclear bodies" "HPA057803: " "unprognostic (5.95e-3)" "unprognostic (2.82e-1)" "unprognostic (1.07e-1)" "unprognostic (7.99e-3)" "unprognostic (2.69e-1)" "unprognostic (3.75e-2)" "unprognostic (1.60e-2)" "unprognostic (2.07e-1)" "unprognostic (1.54e-1)" "unprognostic (4.92e-3)" "unprognostic (3.03e-2)" "unprognostic (1.52e-1)" "unprognostic (1.27e-1)" "unprognostic (4.55e-2)" "unprognostic (2.70e-1)" "unprognostic (5.18e-3)" "unprognostic (1.89e-1)" "unprognostic (6.10e-2)" "unprognostic (2.32e-1)" "unprognostic (1.86e-1)" RASL12 RIS ENSG00000103710 "RAS like family 12" Q9NYN1 15 65053337-65076690 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 273.6" "Cell type enhanced" "Detected in some" "Astrocytes: 63.8;Epididymal efferent duct absorptive cells: 36.0;Granulosa cells: 51.9;Müller glia: 26.4;Pericytes: 59.8;Peritubular myoid cells: 68.6;Pituicytes/FSCs: 33.6;Retinal pigment epithelial cells: 93.8;Smooth muscle cells: 170.5;Vascular smooth muscle cells: 121.1" "Group enriched" "Detected in some" 51 "astrocyte: 109.5;pericyte: 112.9;vascular associated smooth muscle cell: 104.5" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 36.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 6.5;testis cancer: 15.9" "Adipose subcutaneous - Smooth muscle cells, Kidney - Fibroblasts, Prostate - Smooth muscle cells, Skin - Smooth muscle cells, Spleen - Fibroblasts_1, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 19: Astrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 62: Smooth muscle cells - Muscle contraction" 4 "unprognostic (1.18e-1)" "unprognostic (2.57e-2)" "unprognostic (3.19e-2)" "unprognostic (6.04e-2)" "unprognostic (2.15e-2)" "unprognostic (2.17e-1)" "unprognostic (2.88e-1)" "unprognostic (3.07e-1)" "unprognostic (2.20e-2)" "unprognostic (6.11e-3)" "unprognostic (2.13e-3)" "potential prognostic favorable (7.09e-5)" "unprognostic (8.18e-2)" "unprognostic (4.73e-2)" "unprognostic (2.15e-1)" "unprognostic (3.94e-2)" "unprognostic (7.54e-2)" "unprognostic (7.39e-3)" "unprognostic (9.43e-3)" "unprognostic (4.15e-1)" "unprognostic (8.25e-3)" "unprognostic (6.42e-2)" "unprognostic (6.85e-2)" "unprognostic (5.44e-2)" "unprognostic (1.02e-2)" "unprognostic (1.17e-1)" "unprognostic (3.20e-3)" "unprognostic (2.07e-2)" "unprognostic (4.73e-2)" "unprognostic (8.42e-2)" "unprognostic (1.82e-2)" RASSF1 "123F2, NORE2A, RDA32, REH3P21" ENSG00000068028 "Ras association domain family member 1" Q9NS23 3 50329782-50340980 "Human disease related genes, Predicted intracellular proteins, RAS pathway related proteins" "Cell cycle" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cells: 152.2" "Cell type enhanced" "Detected in all" "leukocyte: 158.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 258.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040735 Approved NA Yes "Cluster 32: Basophils - Transcription" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 6: Non-specific - Immune response" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 103: Non-specific - Basic cellular processes" 52 "HPA040735: " "unprognostic (3.70e-2)" "unprognostic (1.34e-1)" "unprognostic (4.43e-2)" "unprognostic (6.26e-2)" "unprognostic (6.45e-2)" "unprognostic (3.17e-1)" "unprognostic (1.25e-3)" "unprognostic (2.31e-1)" "unprognostic (1.38e-3)" "unprognostic (4.63e-1)" "unprognostic (2.96e-1)" "unprognostic (5.09e-2)" "unprognostic (1.14e-1)" "potential prognostic unfavorable (6.04e-4)" "unprognostic (7.60e-3)" "unprognostic (9.78e-3)" "unprognostic (1.05e-1)" "unprognostic (1.32e-1)" "unprognostic (7.68e-2)" "unprognostic (1.84e-2)" "unprognostic (2.23e-2)" "unprognostic (1.09e-1)" "unprognostic (9.18e-2)" "unprognostic (7.18e-2)" "unprognostic (1.92e-1)" "unprognostic (5.06e-3)" "unprognostic (6.59e-2)" "unprognostic (2.71e-2)" "unprognostic (5.54e-2)" "unprognostic (1.92e-2)" "unprognostic (5.30e-2)" RASSF10 ENSG00000189431 "Ras association domain family member 10" A6NK89 11 13009316-13012119 "Predicted intracellular proteins" Neurogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 5.7;salivary gland: 4.3;skin 1: 6.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 11.4;Basal prostatic cells: 10.8;Endometrial glandular cells: 13.2;Endometrial luminal cells: 10.7;Enteric stem cells: 11.3;Epididymal basal cells: 13.3;Epididymal efferent duct ciliated cells: 10.9;Esophageal apical cells: 22.0;Esophageal basal cells: 33.4;Esophageal suprabasal cells: 20.8;Paneth cells: 11.6;Parietal cells: 10.6;Respiratory basal cells: 11.4;Respiratory ciliated cells: 12.2;Submucosal glandular cells: 10.2" "Group enriched" "Detected in some" 6 "astrocyte: 2.1;central nervous system macrophage: 3.8;committed oligodendrocyte precursor: 4.1;ependymal cell: 5.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 11.6" "Adipose subcutaneous - Smooth muscle cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA040406 Approved Vesicles,Cytosol NA NA "Cluster 58: Skin - Keratinization" "Cluster 46: Brainstem - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 20 Vesicles Cytosol "HPA040406: " "unprognostic (1.09e-2)" "unprognostic (3.66e-2)" "unprognostic (7.30e-2)" "unprognostic (2.68e-2)" "unprognostic (7.18e-2)" "unprognostic (2.06e-2)" "unprognostic (1.28e-2)" "unprognostic (9.28e-3)" "unprognostic (2.06e-3)" "unprognostic (8.20e-3)" "unprognostic (1.56e-2)" "potential prognostic favorable (3.51e-4)" "unprognostic (2.14e-1)" "unprognostic (4.01e-1)" "unprognostic (1.53e-2)" "unprognostic (1.04e-1)" "unprognostic (3.11e-1)" "unprognostic (2.53e-1)" "unprognostic (1.52e-1)" "unprognostic (1.59e-1)" "unprognostic (5.85e-2)" "unprognostic (1.33e-1)" "unprognostic (1.28e-1)" RASSF2 "CENP-34, KIAA0168" ENSG00000101265 "Ras association domain family member 2" P50749 20 4780023-4823608 "Predicted intracellular proteins" "Cell cycle" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 286.3;retina: 150.9" "Cell type enhanced" "Detected in many" "cDC: 153.9;Monocyte progenitors: 197.2;monocytes: 230.2;Neutrophil progenitors: 424.5;Neutrophils: 1212.7;Oligodendrocytes: 121.6;pDCs: 122.2;Peritubular myoid cells: 180.0;Rod photoreceptor cells: 323.5" "Group enriched" "Detected in many" 7 "Bergmann glia: 58.8;central nervous system macrophage: 96.6;committed oligodendrocyte precursor: 51.1;fibroblast: 69.9;leukocyte: 53.5;oligodendrocyte: 182.8;oligodendrocyte precursor cell: 73.6" "Cancer enriched" "Detected in all" 5 "Glioblastoma Multiforme (TCGA): 79.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 37.1;lymphoma: 46.2" "Adrenal gland - Fibroblasts, Pituitary gland - Fibroblasts, Skin - Fibroblasts_1, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051200 Uncertain Supported "Nucleoplasm,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 55: Lymphoma - Immune response" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 39 Nucleoplasm "Golgi apparatus, Plasma membrane, Cytosol" "HPA051200: " "unprognostic (3.97e-2)" "unprognostic (9.17e-2)" "unprognostic (3.88e-2)" "unprognostic (6.80e-3)" "unprognostic (1.24e-1)" "unprognostic (4.39e-1)" "unprognostic (2.95e-1)" "unprognostic (3.83e-1)" "unprognostic (3.47e-3)" "unprognostic (2.40e-1)" "potential prognostic favorable (6.63e-4)" "unprognostic (1.58e-2)" "unprognostic (1.34e-1)" "unprognostic (2.02e-1)" "unprognostic (4.37e-3)" "unprognostic (6.83e-3)" "unprognostic (1.26e-2)" "unprognostic (6.66e-2)" "unprognostic (2.15e-1)" "unprognostic (2.49e-3)" "unprognostic (6.04e-2)" "unprognostic (1.01e-1)" "unprognostic (1.17e-1)" "unprognostic (2.97e-1)" "unprognostic (3.28e-1)" "unprognostic (1.44e-1)" "unprognostic (2.40e-2)" "unprognostic (1.95e-2)" "unprognostic (3.23e-1)" "unprognostic (1.53e-1)" "unprognostic (5.42e-2)" RASSF3 ENSG00000153179 "Ras association domain family member 3" Q86WH2 12 64507001-64697564 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 136.9" "Cell type enhanced" "Detected in many" "cDC: 283.2;monocytes: 462.7;Neutrophils: 1471.0" "Group enriched" "Detected in all" 4 "central nervous system macrophage: 180.0;choroid plexus epithelial cell: 226.7;endothelial cell: 286.0;leukocyte: 300.1;thalamic excitatory: 87.3;vascular associated smooth muscle cell: 136.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 6 "neutrophil: 124.5" "Lineage enriched" "Detected in all" 6 "granulocytes: 124.5" "Cancer enhanced" "Detected in all" "prostate cancer: 128.3" "Prostate - Smooth muscle cells, Testis - Spermatogonia, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022664, CAB034035, HPA038469" Supported Supported "Plasma membrane,Cytosol" NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" 26 "Plasma membrane, Cytosol" "CAB022664: , CAB034035: , HPA038469: " "unprognostic (1.74e-1)" "unprognostic (1.33e-1)" "unprognostic (1.57e-1)" "unprognostic (7.55e-2)" "unprognostic (4.07e-2)" "unprognostic (2.50e-1)" "unprognostic (1.49e-1)" "unprognostic (5.99e-2)" "unprognostic (1.77e-2)" "unprognostic (8.31e-2)" "potential prognostic favorable (8.23e-5)" "unprognostic (2.53e-2)" "unprognostic (4.60e-2)" "unprognostic (2.46e-3)" "unprognostic (2.06e-1)" "unprognostic (2.21e-1)" "unprognostic (1.03e-1)" "unprognostic (3.91e-2)" "unprognostic (8.64e-2)" "unprognostic (1.09e-1)" "unprognostic (2.90e-2)" "unprognostic (1.75e-2)" "unprognostic (3.83e-2)" "unprognostic (6.34e-2)" "unprognostic (1.22e-1)" "unprognostic (1.83e-1)" "unprognostic (3.75e-1)" "unprognostic (1.99e-3)" "unprognostic (9.86e-2)" "unprognostic (1.16e-1)" "unprognostic (6.92e-2)" RASSF4 "AD037, MGC44914" ENSG00000107551 "Ras association domain family member 4" Q9H2L5 10 44959407-44995891 "Predicted intracellular proteins" "Cell cycle" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 76.5" "Cell type enhanced" "Detected in many" "Adipocytes: 182.4;Astrocytes: 173.2;Bergmann glia: 303.0;cDC: 155.8;Epididymal efferent duct absorptive cells: 164.4;Hofbauer cells: 285.5;Müller glia: 265.5;Myosatellite cells: 200.0;Proximal tubule cells: 407.1;Schwann cells: 147.6" "Cell type enhanced" "Detected in all" "astrocyte: 223.0;Bergmann glia: 323.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "classical monocyte: 85.0;intermediate monocyte: 64.0;myeloid DC: 84.3;non-classical monocyte: 38.2" "Group enriched" "Detected in many" 10 "dendritic cells: 84.3;monocytes: 85.0" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Macrophages, Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038834, HPA077069" Approved Approved "Nucleoplasm,Nucleoli,Cell Junctions,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 88: Proximal tubular cells - Transmembrane transport" 11 "Nucleoplasm, Nucleoli" "Cell Junctions, Cytokinetic bridge, Mitotic spindle, Cytosol" "HPA038834: , HPA077069: " "unprognostic (2.22e-1)" "unprognostic (9.38e-3)" "unprognostic (5.62e-2)" "unprognostic (2.13e-3)" "unprognostic (6.99e-2)" "unprognostic (3.36e-2)" "unprognostic (1.92e-1)" "potential prognostic favorable (2.25e-5)" "unprognostic (1.04e-1)" "unprognostic (2.15e-2)" "unprognostic (1.45e-3)" "unprognostic (1.73e-1)" "unprognostic (5.00e-2)" "unprognostic (9.67e-3)" "unprognostic (1.32e-2)" "unprognostic (2.32e-1)" "unprognostic (2.12e-3)" "unprognostic (1.27e-1)" "unprognostic (7.43e-2)" "unprognostic (1.72e-1)" "unprognostic (7.25e-2)" "unprognostic (3.11e-2)" "unprognostic (1.51e-2)" "unprognostic (3.76e-1)" "unprognostic (8.88e-2)" "unprognostic (5.09e-3)" "unprognostic (1.82e-2)" "unprognostic (4.76e-2)" "unprognostic (1.79e-1)" "unprognostic (3.76e-2)" "unprognostic (3.28e-1)" RASSF5 "Maxp1, NORE1, RAPL" ENSG00000266094 "Ras association domain family member 5" Q8WWW0 1 206507531-206589448 "Predicted intracellular proteins, RAS pathway related proteins" Apoptosis "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 103.2;lymphoid tissue: 77.5" "Cell type enhanced" "Detected in many" "cDC: 143.9;Esophageal apical cells: 200.4;Mast cells: 175.2;monocytes: 143.1;Neutrophil progenitors: 121.8;Neutrophils: 428.4;NK-cells: 120.6;Urothelial cells: 176.7" "Cell type enhanced" "Detected in many" "leukocyte: 112.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 7 "Leukemia: 50.0;lymphoma: 49.3;Myeloma: 81.2" "Adipose subcutaneous - Adipose progenitor cells, Lung - NK-cells (Lung), Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070480 Approved NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 49 "HPA070480: " "unprognostic (7.72e-2)" "unprognostic (3.34e-2)" "unprognostic (6.68e-2)" "unprognostic (6.19e-3)" "unprognostic (1.95e-1)" "unprognostic (3.93e-1)" "unprognostic (1.02e-1)" "unprognostic (1.74e-2)" "unprognostic (2.03e-1)" "unprognostic (1.02e-3)" "unprognostic (1.02e-1)" "unprognostic (3.03e-3)" "unprognostic (4.80e-2)" "unprognostic (1.39e-2)" "unprognostic (1.62e-2)" "unprognostic (1.84e-1)" "unprognostic (3.37e-2)" "unprognostic (3.93e-1)" "unprognostic (1.32e-3)" "unprognostic (1.24e-1)" "unprognostic (9.16e-2)" "unprognostic (8.79e-2)" "unprognostic (1.20e-1)" "unprognostic (2.79e-1)" "unprognostic (1.84e-1)" "unprognostic (1.60e-2)" "unprognostic (2.38e-1)" "unprognostic (8.49e-2)" RASSF6 ENSG00000169435 "Ras association domain family member 6" Q6ZTQ3 4 73571550-73620631 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 28.5;stomach 1: 33.0" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 230.9;Breast lactating cells: 249.6;Foveolar cells: 422.4;Goblet cells: 202.7;Neuroendocrine cells: 202.7;Ocular epithelial cells: 222.7;Prostatic hillock cells: 246.1;Respiratory basal cells: 327.1;Respiratory ionocytes: 307.3;Tuft cells: 1014.5;Urothelial cells: 235.6" "Cell type enriched" "Detected in some" 25 "choroid plexus epithelial cell: 52.4" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 5 "choroid plexus: 11.3" "Immune cell enriched" "Detected in single" 8 "memory B-cell: 2.7" "Lineage enriched" "Detected in single" 13 "B-cells: 2.7" "Cancer enhanced" "Detected in many" "lymphoma: 27.3" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Minor Salivary Gland - Minor salivary gland ductal cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA037712 Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 60: Stomach - Digestion" "Cluster 36: Choroid plexus - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 95: Tuft cells - Chemosensory signaling" 9 "Nucleoplasm, Golgi apparatus" "HPA037712: " "unprognostic (1.46e-1)" "unprognostic (4.95e-2)" "unprognostic (9.07e-2)" "unprognostic (4.34e-2)" "unprognostic (5.72e-2)" "unprognostic (1.07e-1)" "unprognostic (3.64e-2)" "unprognostic (5.36e-2)" "potential prognostic favorable (9.39e-7)" "unprognostic (9.56e-2)" "unprognostic (2.73e-1)" "unprognostic (1.23e-1)" "unprognostic (1.56e-1)" "unprognostic (1.96e-2)" "unprognostic (7.12e-2)" "unprognostic (1.13e-1)" "unprognostic (4.57e-2)" "unprognostic (7.93e-2)" "unprognostic (1.84e-2)" "unprognostic (1.89e-1)" "unprognostic (2.98e-2)" "unprognostic (1.01e-1)" "unprognostic (6.27e-2)" RASSF7 "C11orf13, CFAP88, FAP88, HRAS1, HRC1" ENSG00000099849 "Ras association domain family member 7" Q02833 11 560404-564025 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 121.5" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 35.8;Loop of henle epithelial cells: 44.5;Other brain neurons: 13.3;Papillary tip epithelial cells: 36.8;Podocytes: 45.9;Proximal tubule cells: 37.2;Renal collecting duct intercalated cells: 22.7;Renal collecting duct principal cells: 55.2;Renal connecting tubule cells: 38.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA078015 Supported "Centriolar satellite" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 64: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 16 "Centriolar satellite" "HPA078015: " "unprognostic (2.23e-1)" "unprognostic (1.16e-2)" "unprognostic (3.73e-1)" "unprognostic (3.13e-3)" "unprognostic (2.31e-1)" "unprognostic (3.28e-2)" "potential prognostic unfavorable (6.54e-4)" "unprognostic (8.16e-2)" "unprognostic (1.54e-2)" "unprognostic (6.42e-2)" "potential prognostic unfavorable (4.08e-4)" "unprognostic (5.36e-2)" "unprognostic (9.14e-2)" "potential prognostic unfavorable (5.46e-4)" "unprognostic (1.14e-1)" "unprognostic (9.92e-2)" "unprognostic (1.59e-1)" "unprognostic (1.73e-1)" "unprognostic (7.11e-2)" "unprognostic (1.06e-1)" "unprognostic (5.92e-2)" "unprognostic (2.82e-1)" "potential prognostic unfavorable (2.77e-4)" "unprognostic (5.41e-2)" "unprognostic (1.08e-1)" "unprognostic (2.87e-2)" "unprognostic (9.57e-2)" "unprognostic (2.63e-2)" "unprognostic (3.14e-1)" "unprognostic (1.43e-1)" "unprognostic (1.36e-1)" RASSF8 "C12orf2, HoJ-1" ENSG00000123094 "Ras association domain family member 8" Q8NHQ8 12 25958232-26079892 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 55.6" "Cell type enhanced" "Detected in many" "Early spermatids: 660.7;Epicardial cells: 893.7;Late spermatids: 1047.8;Microglia: 620.7;Podocytes: 604.0;Retinal horizontal cells: 1322.2" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 706.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038163, HPA038164" Uncertain Approved Mitochondria,Cytosol NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 57: Testis - Spermatogenesis" "Cluster 44: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 26 "Mitochondria, Cytosol" "HPA038163: , HPA038164: " "unprognostic (1.48e-2)" "unprognostic (3.75e-1)" "unprognostic (5.62e-2)" "unprognostic (1.49e-1)" "unprognostic (1.40e-1)" "unprognostic (1.37e-1)" "unprognostic (2.25e-1)" "unprognostic (4.38e-3)" "unprognostic (1.65e-1)" "unprognostic (4.16e-3)" "potential prognostic favorable (1.13e-5)" "unprognostic (1.68e-2)" "unprognostic (6.99e-2)" "unprognostic (6.33e-3)" "unprognostic (9.71e-2)" "unprognostic (1.21e-1)" "unprognostic (1.48e-1)" "unprognostic (9.39e-3)" "unprognostic (2.73e-1)" "unprognostic (4.43e-3)" "unprognostic (1.72e-2)" "unprognostic (1.99e-1)" "unprognostic (2.08e-1)" "unprognostic (2.41e-1)" "unprognostic (1.48e-1)" "unprognostic (2.13e-3)" "unprognostic (2.67e-1)" "potential prognostic unfavorable (3.14e-4)" "unprognostic (3.24e-1)" "unprognostic (6.82e-2)" "unprognostic (4.25e-2)" RASSF9 "P-CIP1, PAMCI" ENSG00000198774 "Ras association domain family member 9" O75901 12 85800703-85836409 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ependymal cells: 286.0;Epididymal basal cells: 71.2;Fallopian secretory cells: 105.1;Lymphatic endothelial cells: 106.2;Pancreatic duct cells: 91.2;Respiratory basal cells: 78.7;Respiratory deuterosomal cells: 66.3;Respiratory secretory cells: 102.1;Transitional alveolar cells: 79.9" "Cell type enriched" "Detected in some" 15 "ependymal cell: 365.5" "Cancer enhanced" "Detected in many" "Lung Squamous Cell Carcinoma (TCGA): 9.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 5.2" "Minor Salivary Gland - Endothelial cells, Skeletal muscle - Fibroblasts, Spleen - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039428, HPA039678" Approved NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 46: Brainstem - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 34: Ciliated cells - Cilia assembly & function" 1 "HPA039428: , HPA039678: " "unprognostic (1.59e-2)" "unprognostic (1.92e-2)" "unprognostic (1.16e-1)" "unprognostic (1.65e-2)" "unprognostic (7.53e-2)" "unprognostic (2.63e-2)" "potential prognostic favorable (2.31e-4)" "unprognostic (9.86e-3)" "unprognostic (1.67e-2)" "unprognostic (1.80e-1)" "unprognostic (5.21e-2)" "unprognostic (2.34e-2)" "unprognostic (1.72e-3)" "unprognostic (9.31e-2)" "unprognostic (1.27e-1)" "unprognostic (1.46e-2)" "unprognostic (2.14e-1)" "unprognostic (1.49e-1)" "unprognostic (6.26e-2)" "unprognostic (5.40e-2)" "unprognostic (6.30e-2)" RAVER1 KIAA1978 ENSG00000161847 "Ribonucleoprotein, PTB binding 1" 19 10316212-10333529 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043575, HPA049457" Enhanced Supported Nucleoplasm NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 49: Non-specific - Transcription" "Cluster 46: Brainstem - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 10 Nucleoplasm "HPA043575: , HPA049457: " "unprognostic (7.41e-2)" "unprognostic (1.27e-1)" "unprognostic (1.09e-1)" "unprognostic (3.80e-3)" "unprognostic (9.48e-2)" "unprognostic (2.05e-1)" "unprognostic (1.56e-1)" "unprognostic (9.11e-2)" "unprognostic (1.95e-2)" "unprognostic (2.05e-1)" "potential prognostic favorable (2.85e-4)" "unprognostic (3.60e-1)" "unprognostic (3.27e-1)" "unprognostic (1.55e-1)" "unprognostic (5.66e-2)" "unprognostic (1.06e-2)" "unprognostic (3.28e-2)" "unprognostic (2.24e-1)" "unprognostic (1.43e-1)" "unprognostic (1.19e-1)" "unprognostic (1.52e-1)" "unprognostic (1.72e-2)" "unprognostic (1.35e-1)" "unprognostic (2.19e-2)" "unprognostic (1.63e-2)" "potential prognostic favorable (5.61e-4)" "unprognostic (1.06e-2)" "unprognostic (1.65e-2)" "unprognostic (1.25e-1)" "unprognostic (7.03e-2)" "unprognostic (2.79e-1)" RAVER2 "FLJ10770, KIAA1579" ENSG00000162437 "Ribonucleoprotein, PTB binding 2" Q9HCJ3 1 64745075-64833232 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 150.3;Bergmann glia: 141.4;Choroid plexus epithelial cells: 178.6;Ependymal cells: 159.2;Thyrotrophs: 162.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 12 "basophil: 6.2" "Lineage enriched" "Detected in single" 12 "granulocytes: 6.2" "Low cancer specificity" "Detected in all" "Skeletal muscle - Skeletal myocytes, Testis - Peritubular cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045785 Approved Approved Nucleoplasm NA NA "Cluster 41: Basophils - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 11: Neuronal - Sensory perception" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" Nucleoplasm "HPA045785: " "unprognostic (2.13e-1)" "unprognostic (2.41e-1)" "unprognostic (2.66e-1)" "unprognostic (6.30e-3)" "unprognostic (3.92e-2)" "unprognostic (7.22e-2)" "unprognostic (8.21e-2)" "unprognostic (2.19e-1)" "unprognostic (8.68e-2)" "unprognostic (1.61e-1)" "validated prognostic favorable (9.06e-12)" "validated prognostic favorable (2.53e-4)" "unprognostic (6.44e-2)" "unprognostic (4.81e-3)" "unprognostic (6.72e-2)" "unprognostic (3.34e-1)" "unprognostic (5.92e-2)" "unprognostic (5.59e-3)" "unprognostic (3.68e-2)" "unprognostic (1.10e-1)" "unprognostic (1.20e-1)" "unprognostic (1.78e-1)" "unprognostic (1.95e-3)" "unprognostic (5.57e-2)" "unprognostic (5.95e-3)" "unprognostic (1.83e-1)" "unprognostic (2.23e-1)" "unprognostic (1.75e-1)" "unprognostic (5.11e-2)" "unprognostic (1.98e-2)" "unprognostic (2.79e-1)" RAX "RAX1, RX" ENSG00000134438 "Retina and anterior neural fold homeobox" Q9Y2V3 18 59267035-59274086 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 32 "pituitary gland: 6.8;retina: 14.8" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 188.4;Müller glia: 512.1;Pituicytes/FSCs: 103.7" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "white matter: 2.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 19 "Bone cancer: 3.5" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 42: Retina - Visual perception" "Cluster 55: Non-specific - Transcription" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 11: Muller glia cells - Retinal homeostasis" 1 RAX2 "ARMD6, CORD11, MGC15631, RAXL1" ENSG00000173976 "Retina and anterior neural fold homeobox 2" Q96IS3 19 3769089-3772228 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Sensory transduction, Transcription, Transcription regulation, Vision" DNA-binding "Age-related macular degeneration, Cone-rod dystrophy, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 40 "retina: 59.9" "Group enriched" "Detected in some" 17 "Cone photoreceptor cells: 70.4;Oocytes: 32.2;Rod photoreceptor cells: 123.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "Uterine cancer: 1.9" "Adipose visceral - Mesothelial cells, Pituitary gland - Gonadotropes" "Low region specificity" "Detected in all" HPA052533 Uncertain Approved "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 42: Retina - Visual perception" "Cluster 9: Non-specific - Receptor signaling" "Cluster 1: Neuronal - Visual perception" "Cluster 79: Photoreceptor cells - Phototransduction" "Nuclear speckles" "Nucleoplasm, Cytosol" "HPA052533: " "unprognostic (1.82e-1)" "unprognostic (3.59e-1)" RB1 "OSRC, PPP1R130, RB" ENSG00000139687 "RB transcriptional corepressor 1" P06400 13 48303744-48599436 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Melanocytes: 563.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000095, CAB016687, HPA050082" Supported Supported "Nucleoplasm,Primary cilium transition zone" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 19: Non-specific - Unknown function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 218 Nucleoplasm "Primary cilium transition zone" "CAB000095: , CAB016687: , HPA050082: " "unprognostic (1.68e-1)" "unprognostic (3.92e-2)" "unprognostic (5.31e-2)" "unprognostic (1.54e-2)" "unprognostic (2.25e-2)" "unprognostic (8.89e-2)" "unprognostic (6.26e-2)" "unprognostic (3.24e-1)" "unprognostic (1.04e-1)" "unprognostic (1.12e-1)" "potential prognostic favorable (2.72e-8)" "unprognostic (4.20e-2)" "unprognostic (1.61e-1)" "unprognostic (1.82e-2)" "unprognostic (3.78e-2)" "unprognostic (3.83e-2)" "unprognostic (3.89e-3)" "unprognostic (1.88e-1)" "unprognostic (1.06e-1)" "potential prognostic unfavorable (9.67e-4)" "unprognostic (1.29e-3)" "unprognostic (2.31e-2)" "unprognostic (1.66e-1)" "unprognostic (1.50e-1)" "unprognostic (1.01e-1)" "unprognostic (9.63e-2)" "unprognostic (4.24e-2)" "unprognostic (3.03e-2)" "unprognostic (4.80e-2)" "unprognostic (1.21e-1)" "unprognostic (2.50e-1)" RB1CC1 "ATG17, Cc1, DRAGOU14, FIP200, KIAA0203, PPP1R131" ENSG00000023287 "RB1 inducible coiled-coil 1" Q8TDY2 8 52622458-52745843 "Human disease related genes, Predicted intracellular proteins" "Autophagy, Cell cycle, Transcription, Transcription regulation" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 716.1;Epicardial cells: 730.0;Neutrophils: 719.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024391, HPA053049" Approved Supported "Nuclear membrane,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 53: Neurons - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 71 Cytosol "Nuclear membrane" "HPA024391: , HPA053049: " "unprognostic (2.45e-1)" "unprognostic (1.91e-3)" "unprognostic (1.26e-1)" "unprognostic (1.76e-3)" "unprognostic (1.72e-1)" "unprognostic (1.33e-1)" "unprognostic (2.90e-1)" "potential prognostic favorable (2.72e-4)" "unprognostic (1.51e-2)" "potential prognostic unfavorable (9.96e-5)" "potential prognostic favorable (2.74e-4)" "unprognostic (1.77e-2)" "unprognostic (4.06e-2)" "unprognostic (9.84e-2)" "unprognostic (1.59e-2)" "unprognostic (9.51e-2)" "unprognostic (7.50e-2)" "unprognostic (3.42e-2)" "unprognostic (6.58e-3)" "unprognostic (2.01e-1)" "potential prognostic unfavorable (1.40e-4)" "potential prognostic unfavorable (3.43e-4)" "unprognostic (3.15e-3)" "unprognostic (2.64e-1)" "unprognostic (2.37e-2)" "unprognostic (1.31e-2)" "unprognostic (1.85e-1)" "unprognostic (3.66e-2)" "unprognostic (3.24e-1)" "unprognostic (1.29e-2)" "unprognostic (9.80e-2)" RBAK ZNF769 ENSG00000146587 "RB associated KRAB zinc finger" Q9NYW8 7 5045821-5069487 "Metabolic proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 7 "Astrocytes: 14.6;Bergmann glia: 13.7;Brain excitatory neurons: 13.9;Brain inhibitory neurons: 14.5;Choroid plexus epithelial cells: 17.9;Ependymal cells: 13.3;Microglia: 12.8;Oligodendrocyte progenitor cells: 14.9;Oligodendrocytes: 15.0;Other brain neurons: 15.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071231 Supported Nucleoplasm NA NA "Cluster 61: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 67: Non-specific - Unknown function" "Cluster 22: Non-specific - Basic cellular functions" 25 Nucleoplasm "HPA071231: " "unprognostic (5.04e-2)" "unprognostic (2.48e-2)" "unprognostic (2.61e-1)" "unprognostic (2.68e-2)" "unprognostic (1.76e-1)" "unprognostic (1.39e-1)" "unprognostic (3.72e-1)" "unprognostic (1.02e-2)" "unprognostic (2.46e-1)" "unprognostic (4.16e-3)" "unprognostic (2.56e-3)" "unprognostic (5.72e-2)" "unprognostic (1.19e-1)" "unprognostic (1.33e-1)" "unprognostic (8.66e-2)" "unprognostic (1.21e-1)" "unprognostic (1.70e-2)" "unprognostic (1.87e-2)" "unprognostic (9.31e-2)" "unprognostic (2.02e-2)" "unprognostic (8.67e-3)" "unprognostic (1.96e-1)" "potential prognostic unfavorable (2.74e-4)" "unprognostic (4.75e-2)" "unprognostic (4.23e-2)" "unprognostic (1.02e-1)" "unprognostic (4.50e-2)" "unprognostic (1.47e-1)" "unprognostic (9.06e-2)" "unprognostic (1.22e-2)" "unprognostic (4.02e-1)" RBAK-RBAKDN ENSG00000272968 "RBAK-RBAKDN readthrough" 7 4983718-5073221 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 55 "testis: 54.5" "Group enriched" "Detected in many" 4 "Distal convoluted tubule cells: 57.9;Early spermatids: 27.8;Late primary spermatocytes: 37.9;Loop of henle epithelial cells: 49.2;Papillary tip epithelial cells: 39.4;Podocytes: 60.4;Proximal tubule cells: 49.5;Renal collecting duct intercalated cells: 46.7;Renal collecting duct principal cells: 46.8;Renal connecting tubule cells: 55.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 67: Non-specific - Unknown function" "Cluster 105: Non-specific - Mixed function" "unprognostic (9.17e-2)" "unprognostic (1.13e-2)" "unprognostic (8.88e-2)" "unprognostic (4.54e-3)" "unprognostic (1.19e-1)" "unprognostic (2.20e-1)" "potential prognostic unfavorable (6.29e-4)" "unprognostic (3.73e-1)" "unprognostic (1.02e-1)" "unprognostic (1.01e-2)" "unprognostic (1.50e-1)" "unprognostic (2.29e-3)" "unprognostic (2.35e-1)" "unprognostic (2.47e-2)" RBBP4 "lin-53, NURF55, RbAp48" ENSG00000162521 "RB binding protein 4, chromatin remodeling factor" Q09028 1 32651142-32686211 "Cancer-related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair, DNA replication, Transcription, Transcription regulation" "Chaperone, Chromatin regulator, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "CAB006264, HPA060710, HPA060724" Supported Enhanced Nucleoplasm NA NA 390000 "Cluster 13: Non-specific - Mitochondria" "Cluster 39: Testis - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 262 Nucleoplasm "CAB006264: , HPA060710: , HPA060724: " "unprognostic (1.66e-2)" "unprognostic (1.45e-1)" "potential prognostic unfavorable (9.68e-4)" "unprognostic (1.95e-1)" "unprognostic (9.73e-3)" "unprognostic (1.47e-1)" "unprognostic (2.01e-2)" "unprognostic (1.87e-2)" "unprognostic (7.26e-2)" "unprognostic (2.50e-3)" "potential prognostic favorable (2.07e-6)" "unprognostic (1.31e-2)" "unprognostic (1.85e-1)" "unprognostic (1.51e-3)" "unprognostic (1.15e-3)" "unprognostic (3.88e-1)" "unprognostic (3.00e-2)" "unprognostic (2.35e-1)" "unprognostic (2.90e-1)" "unprognostic (7.35e-2)" "unprognostic (7.62e-2)" "unprognostic (6.96e-3)" "unprognostic (1.51e-1)" "unprognostic (8.27e-2)" "unprognostic (1.95e-2)" "unprognostic (2.47e-2)" "unprognostic (2.28e-1)" "unprognostic (9.94e-2)" "unprognostic (2.70e-1)" "unprognostic (7.74e-2)" "unprognostic (1.34e-1)" RBBP5 "RBQ3, SWD1" ENSG00000117222 "RB binding protein 5, histone lysine methyltransferase complex subunit" Q15291 1 205086142-205122015 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049042, HPA058085" Uncertain Supported Nucleoplasm,Nucleoli No No "Cluster 32: Basophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 20: Non-specific - Transcription regulation" 86 "Nucleoplasm, Nucleoli" "HPA049042: , HPA058085: " "unprognostic (5.90e-2)" "unprognostic (1.89e-3)" "unprognostic (1.69e-1)" "unprognostic (4.87e-2)" "unprognostic (2.90e-2)" "unprognostic (2.60e-1)" "unprognostic (3.42e-1)" "unprognostic (5.69e-2)" "unprognostic (4.55e-1)" "unprognostic (7.77e-3)" "potential prognostic favorable (6.45e-5)" "unprognostic (6.90e-2)" "unprognostic (5.29e-3)" "unprognostic (1.05e-2)" "unprognostic (2.38e-1)" "unprognostic (4.83e-2)" "unprognostic (5.54e-2)" "unprognostic (1.38e-1)" "unprognostic (4.82e-3)" "unprognostic (1.60e-1)" "potential prognostic unfavorable (5.87e-4)" "unprognostic (1.29e-1)" "unprognostic (1.70e-2)" "unprognostic (2.54e-2)" "unprognostic (2.96e-3)" "unprognostic (1.26e-1)" "unprognostic (7.34e-2)" "unprognostic (2.83e-2)" "unprognostic (1.59e-1)" "unprognostic (3.80e-2)" "unprognostic (4.12e-2)" RBBP6 "P2P-R, PACT, SNAMA" ENSG00000122257 "RB binding protein 6, ubiquitin ligase" Q7Z6E9 16 24537693-24572863 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA replication, Host-virus interaction, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 135.4" "Cell type enhanced" "Detected in all" "Platelets: 1001.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032866, HPA041725, HPA043544" Approved Enhanced "Nuclear speckles" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 31: Non-specific - Transcription" "Cluster 54: Non-specific - Transcription" "Cluster 47: Platelets - Hemostasis" 37 "Nuclear speckles" "CAB032866: , HPA041725: , HPA043544: " "unprognostic (1.93e-1)" "unprognostic (8.85e-2)" "unprognostic (5.39e-2)" "unprognostic (2.59e-2)" "unprognostic (3.18e-1)" "unprognostic (3.09e-2)" "unprognostic (1.91e-2)" "unprognostic (8.47e-2)" "unprognostic (8.64e-2)" "unprognostic (1.30e-2)" "unprognostic (3.28e-1)" "unprognostic (3.29e-2)" "unprognostic (3.28e-2)" "potential prognostic unfavorable (4.87e-4)" "unprognostic (3.61e-2)" "unprognostic (1.13e-1)" "unprognostic (1.93e-1)" "unprognostic (5.40e-2)" "unprognostic (6.57e-3)" "unprognostic (1.71e-2)" "unprognostic (2.46e-1)" "unprognostic (2.23e-1)" "unprognostic (2.04e-3)" "unprognostic (1.13e-1)" "unprognostic (9.17e-3)" "unprognostic (7.27e-2)" "unprognostic (5.18e-3)" "unprognostic (1.03e-1)" "unprognostic (2.77e-1)" "unprognostic (2.25e-2)" "unprognostic (8.47e-2)" RBBP7 RbAp46 ENSG00000102054 "RB binding protein 7, chromatin remodeling factor" Q16576 X 16839283-16870362 "Predicted intracellular proteins" "DNA replication, Transcription, Transcription regulation" "Chaperone, Chromatin regulator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 529.8;Epididymal principal cells: 457.5;Migrating cytotrophoblasts: 398.4;Oocytes: 327.0;Syncytiotrophoblasts: 621.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Smooth muscle cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037084, HPA060710, HPA060724" Supported Enhanced Nucleoplasm NA NA 190000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 36: Non-specific - mRNA processing" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 206 Nucleoplasm "CAB037084: , HPA060710: , HPA060724: " "unprognostic (2.31e-1)" "unprognostic (6.28e-2)" "unprognostic (2.50e-1)" "unprognostic (1.14e-1)" "unprognostic (5.12e-3)" "unprognostic (8.06e-2)" "unprognostic (1.24e-2)" "unprognostic (2.05e-3)" "unprognostic (2.21e-1)" "potential prognostic unfavorable (2.75e-5)" "potential prognostic favorable (9.91e-6)" "unprognostic (1.60e-2)" "unprognostic (1.69e-1)" "potential prognostic unfavorable (1.13e-4)" "unprognostic (1.66e-3)" "unprognostic (3.65e-3)" "unprognostic (7.13e-2)" "unprognostic (5.63e-3)" "unprognostic (4.65e-2)" "unprognostic (1.08e-1)" "unprognostic (1.05e-1)" "unprognostic (3.63e-2)" "unprognostic (2.10e-1)" "unprognostic (4.15e-2)" "unprognostic (7.00e-3)" "unprognostic (9.69e-3)" "unprognostic (4.36e-2)" "unprognostic (2.96e-1)" "unprognostic (1.05e-1)" "unprognostic (1.38e-1)" "unprognostic (5.09e-2)" RBBP8 "COM1, CtIP, RIM, SCKL2" ENSG00000101773 "RB binding protein 8, endonuclease" Q99708 18 22798261-23026488 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Meiosis, Mitosis" "DNA-binding, Endonuclease, Hydrolase, Nuclease" "Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 287.6;Choroid plexus epithelial cells: 300.7;Renal connecting tubule cells: 265.5" "Cell type enriched" "Detected in all" 7 "choroid plexus epithelial cell: 307.9" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "choroid plexus: 83.7" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 37.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast myoepithelial cells, Kidney - Endothelial cells, Skin - Mitotic cells (Skin), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039890, HPA052946" Approved Supported Nucleoplasm NA Yes "Cluster 40: Monocytes - Innate immune response" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 103: Non-specific - Basic cellular processes" 60 Nucleoplasm "HPA039890: , HPA052946: " "unprognostic (8.85e-2)" "unprognostic (1.72e-3)" "unprognostic (4.06e-2)" "unprognostic (1.05e-1)" "unprognostic (1.71e-2)" "unprognostic (1.88e-1)" "unprognostic (1.13e-1)" "unprognostic (5.00e-2)" "unprognostic (3.09e-1)" "unprognostic (7.81e-2)" "unprognostic (8.54e-2)" "unprognostic (3.73e-2)" "unprognostic (3.94e-1)" "unprognostic (2.49e-3)" "potential prognostic unfavorable (3.47e-4)" "unprognostic (9.35e-2)" "unprognostic (1.10e-1)" "unprognostic (9.82e-2)" "unprognostic (2.52e-2)" "unprognostic (1.01e-2)" "unprognostic (2.19e-1)" "unprognostic (1.07e-3)" "unprognostic (1.06e-2)" "unprognostic (6.10e-3)" "unprognostic (3.77e-1)" "unprognostic (5.51e-2)" "potential prognostic unfavorable (3.90e-4)" "unprognostic (3.53e-3)" "unprognostic (1.64e-1)" "unprognostic (2.87e-3)" "unprognostic (1.92e-1)" RBBP8NL "C20orf151, dJ908M14.3" ENSG00000130701 "RBBP8 N-terminal like" Q8NC74 20 62410237-62427539 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 8.7" "Cell type enhanced" "Detected in many" "Colonocytes: 56.1;Early spermatids: 22.4;Enteric stem cells: 27.0;Enteric transient amplifying cells: 27.0;Enterocytes: 143.5;Esophageal apical cells: 30.1;Goblet cells: 58.3;Neuroendocrine cells: 34.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 7.1" "Colon - Colon enterocytes, Kidney - Ascending Loop of Henle cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA042627 Approved Nucleoplasm,Vesicles NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 7: Liver cancer - Metabolism" "Cluster 1: Enterocytes - Absorption and Digestion" 7 "Nucleoplasm, Vesicles" "HPA042627: " "potential prognostic favorable (4.92e-4)" "unprognostic (8.33e-2)" "unprognostic (1.43e-1)" "unprognostic (3.90e-2)" "unprognostic (2.97e-2)" "unprognostic (2.74e-2)" "unprognostic (1.26e-2)" "unprognostic (5.34e-2)" "unprognostic (3.14e-3)" "unprognostic (1.08e-1)" "unprognostic (1.43e-1)" "unprognostic (1.12e-1)" "unprognostic (2.61e-1)" "unprognostic (1.72e-1)" "unprognostic (2.56e-2)" "unprognostic (3.26e-1)" "unprognostic (2.62e-1)" "unprognostic (4.88e-3)" "unprognostic (2.66e-1)" RBBP9 Bog ENSG00000089050 "RB binding protein 9, serine hydrolase" O75884 20 18486540-18497225 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Respiratory deuterosomal cells: 38.4;Respiratory secretory cells: 35.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 9.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015830, HPA049005" Approved Supported Nucleoplasm NA NA 34000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 3: Rhabdoid - Membrane components" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 3 Nucleoplasm "HPA015830: , HPA049005: " "unprognostic (1.14e-3)" "unprognostic (4.83e-2)" "unprognostic (5.18e-2)" "unprognostic (1.01e-1)" "unprognostic (5.79e-2)" "unprognostic (5.23e-2)" "unprognostic (1.33e-1)" "unprognostic (1.31e-1)" "unprognostic (3.52e-3)" "unprognostic (1.45e-2)" "potential prognostic favorable (1.65e-6)" "unprognostic (9.26e-2)" "unprognostic (2.73e-1)" "unprognostic (1.14e-1)" "unprognostic (7.74e-2)" "unprognostic (5.29e-2)" "unprognostic (2.75e-1)" "unprognostic (8.91e-2)" "unprognostic (1.92e-1)" "unprognostic (8.57e-2)" "unprognostic (2.65e-1)" "unprognostic (1.58e-1)" "unprognostic (4.83e-1)" "unprognostic (8.41e-2)" "unprognostic (4.84e-2)" "unprognostic (1.47e-2)" "unprognostic (1.63e-1)" "unprognostic (1.83e-2)" "unprognostic (2.50e-1)" "unprognostic (1.15e-1)" "unprognostic (6.00e-2)" RBCK1 "C20orf18, HOIL1, RBCK2, RNF54, UBCE7IP3, XAP4, ZRANB4" ENSG00000125826 "RANBP2-type and C3HC4-type zinc finger containing 1" Q9BYM8 20 407498-432139 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" Transferase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 223.4;Late spermatids: 286.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 25: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 74 "unprognostic (6.29e-2)" "unprognostic (8.85e-3)" "unprognostic (2.79e-2)" "unprognostic (1.57e-2)" "unprognostic (7.55e-2)" "unprognostic (7.28e-2)" "unprognostic (3.18e-1)" "unprognostic (7.13e-3)" "unprognostic (1.85e-2)" "unprognostic (3.25e-2)" "potential prognostic unfavorable (7.42e-5)" "unprognostic (1.74e-2)" "unprognostic (2.21e-2)" "potential prognostic unfavorable (1.34e-5)" "unprognostic (6.74e-2)" "potential prognostic unfavorable (7.74e-5)" "unprognostic (2.28e-1)" "unprognostic (8.25e-3)" "unprognostic (5.53e-2)" "unprognostic (2.27e-1)" "unprognostic (2.11e-2)" "unprognostic (9.39e-2)" "unprognostic (2.77e-2)" "unprognostic (8.50e-2)" "unprognostic (1.06e-1)" "unprognostic (6.65e-2)" "unprognostic (2.06e-1)" "unprognostic (4.80e-2)" "unprognostic (4.79e-2)" "unprognostic (1.01e-1)" "unprognostic (2.82e-1)" RBFA "C18orf22, FLJ21172, HsT169" ENSG00000101546 "Ribosome binding factor A" Q8N0V3 18 80034389-80050651 "Predicted intracellular proteins" "rRNA processing" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 5.4" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "HPA040485, HPA041479" Approved Approved Mitochondria NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 15: Non-specific - Transcription" "Cluster 13: Non-specific - Mixed function" "Cluster 17: Non-specific - RNA processing" 31 Mitochondria "HPA040485: , HPA041479: " "unprognostic (4.32e-2)" "unprognostic (1.26e-1)" "unprognostic (6.60e-2)" "unprognostic (1.06e-1)" "unprognostic (1.80e-1)" "unprognostic (3.13e-2)" "unprognostic (1.28e-3)" "unprognostic (7.53e-2)" "unprognostic (4.31e-2)" "potential prognostic favorable (3.14e-4)" "unprognostic (1.19e-1)" "unprognostic (7.21e-3)" "potential prognostic unfavorable (6.94e-6)" "unprognostic (1.28e-3)" "unprognostic (1.76e-1)" "unprognostic (5.20e-2)" "unprognostic (1.76e-1)" "unprognostic (2.20e-1)" "unprognostic (2.71e-1)" "unprognostic (1.62e-1)" "unprognostic (3.17e-1)" "unprognostic (3.56e-1)" "unprognostic (7.65e-2)" "unprognostic (1.09e-1)" "unprognostic (5.13e-2)" "unprognostic (2.39e-2)" "unprognostic (2.91e-1)" "unprognostic (3.53e-1)" "unprognostic (1.47e-1)" "unprognostic (7.21e-2)" RBFOX1 "A2BP1, FOX-1, HRNBP1" ENSG00000078328 "RNA binding fox-1 homolog 1" Q9NWB1 16 5239802-7713340 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 65.9;skeletal muscle: 80.8;tongue: 41.2" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 6364.6;Brain inhibitory neurons: 6575.7;Epicardial cells: 1423.6;Lactotrophs: 1931.7;Myonuclei: 2310.7;Neutrophil progenitors: 1675.6;Oligodendrocyte progenitor cells: 1432.4;Other brain neurons: 2689.9;Podocytes: 3330.3;Retinal amacrine cells: 2565.0;Retinal ganglion cells: 3692.8;Thymic myoid cells: 1877.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 3.8;lung cancer: 3.6;Neuroblastoma: 4.4;Sarcoma: 3.9" "Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040809, HPA066746, HPA075862" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus,Cytosol" No No "Cluster 25: Non-specific - Basic cellular processes" "Cluster 53: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" 33 Nucleoplasm "Nucleoli fibrillar center, Golgi apparatus, Cytosol" "HPA040809: , HPA066746: , HPA075862: " "unprognostic (2.42e-2)" "unprognostic (4.43e-2)" "unprognostic (3.24e-2)" "unprognostic (2.61e-1)" "unprognostic (2.07e-1)" "unprognostic (7.34e-2)" "unprognostic (2.00e-1)" RBFOX2 "FOX-2, HNRBP2, HRNBP2, RBM9" ENSG00000100320 "RNA binding fox-1 homolog 2" O43251 22 35738736-36028824 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 269.7;Bergmann glia: 319.4;Brain excitatory neurons: 476.0;Brain inhibitory neurons: 476.0;Distal convoluted tubule cells: 319.8;Oligodendrocyte progenitor cells: 348.1;Other brain neurons: 312.4;Papillary tip epithelial cells: 314.8;Renal collecting duct intercalated cells: 294.0;Renal connecting tubule cells: 309.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Minor Salivary Gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006240, HPA006455, HPA075862" Approved Supported Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 104: Brain endothelial cells - Blood brain barrier" 50 Nucleoplasm "HPA006240: , HPA006455: , HPA075862: " "unprognostic (1.41e-1)" "unprognostic (3.03e-1)" "unprognostic (1.26e-2)" "unprognostic (1.45e-1)" "unprognostic (1.71e-1)" "unprognostic (3.24e-1)" "unprognostic (4.89e-3)" "unprognostic (2.50e-2)" "unprognostic (5.35e-3)" "unprognostic (1.43e-3)" "potential prognostic favorable (9.30e-5)" "unprognostic (2.86e-1)" "unprognostic (8.22e-2)" "unprognostic (7.52e-2)" "unprognostic (1.99e-2)" "unprognostic (7.85e-2)" "unprognostic (1.37e-1)" "unprognostic (7.20e-3)" "unprognostic (2.47e-2)" "potential prognostic unfavorable (7.11e-4)" "unprognostic (4.96e-2)" "unprognostic (2.18e-2)" "unprognostic (2.44e-1)" "unprognostic (3.28e-1)" "unprognostic (1.09e-1)" "unprognostic (1.12e-1)" "unprognostic (7.46e-3)" "unprognostic (1.81e-1)" "unprognostic (3.80e-2)" "unprognostic (1.04e-1)" RBFOX3 "FOX-3, HRNBP3, NeuN" ENSG00000167281 "RNA binding fox-1 homolog 3" A6NFN3 17 79089345-79611051 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 273.5;intestine: 81.6;urinary bladder: 78.6" "Group enriched" "Detected in many" 4 "Brain excitatory neurons: 538.2;Brain inhibitory neurons: 172.3;Corticotrophs: 360.0;Lactotrophs: 410.5;Retinal amacrine cells: 249.0;Retinal ganglion cells: 498.3;Smooth muscle cells: 392.3;Somatotrophs: 515.9;Thyrotrophs: 158.7" "Cell type enhanced" "Detected in all" "upper rhombic lip: 1134.8" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 7.3;Testicular Germ Cell Tumor (TCGA): 5.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 8.5;Neuroblastoma: 16.6" "Adrenal gland - Smooth muscle cells, Prostate - Smooth muscle cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030790, HPA075862, CAB078782" Enhanced Supported Supported Nucleoplasm NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 37: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 2 Nucleoplasm "CAB078782: , HPA030790: , HPA075862: " "unprognostic (2.36e-2)" "unprognostic (4.90e-3)" "unprognostic (6.88e-2)" "unprognostic (2.54e-1)" "unprognostic (8.14e-2)" "unprognostic (1.03e-1)" "unprognostic (8.53e-3)" "unprognostic (1.23e-1)" "unprognostic (1.05e-1)" RBIS C8orf59 ENSG00000176731 "Ribosomal biogenesis factor" Q8N0T1 8 85214048-85220421 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044805, HPA071903" Enhanced Nucleoplasm,Nucleoli,Cytosol No No "Cluster 30: Non-specific - DNA binding" "Cluster 70: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 40: Non-specific - Unknown function" "Cluster 15: Non-specific - Protein processing" 1 "Nucleoplasm, Nucleoli" Cytosol "HPA044805: , HPA071903: " "unprognostic (5.65e-2)" "unprognostic (1.12e-3)" "potential prognostic favorable (7.55e-4)" "unprognostic (1.35e-1)" "unprognostic (1.68e-1)" "unprognostic (1.72e-2)" "unprognostic (5.75e-2)" "unprognostic (2.63e-2)" "unprognostic (8.40e-2)" "potential prognostic unfavorable (3.80e-5)" "unprognostic (2.18e-2)" "unprognostic (1.29e-2)" "unprognostic (7.50e-3)" "unprognostic (1.72e-2)" "unprognostic (5.35e-2)" "unprognostic (9.51e-2)" "unprognostic (1.18e-1)" "unprognostic (1.94e-1)" "unprognostic (3.33e-3)" "unprognostic (5.86e-3)" "potential prognostic unfavorable (2.55e-4)" "unprognostic (2.40e-1)" "unprognostic (1.86e-1)" "unprognostic (2.55e-2)" "unprognostic (3.31e-2)" "unprognostic (3.78e-2)" "unprognostic (7.01e-2)" "unprognostic (2.59e-1)" "unprognostic (9.36e-2)" RBKS "DKFZp686G13268, RBSK" ENSG00000171174 Ribokinase Q9H477 2 27781379-27890681 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 43.4" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 171.4;Mast cells: 212.1;monocytes: 227.4;Neutrophils: 211.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019725, HPA028285" Enhanced Approved Nucleoplasm,Cytosol No No 13000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 76: Non-specific - Metabolism" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 103: Non-specific - Basic cellular processes" 5 Cytosol Nucleoplasm "HPA019725: , HPA028285: " "unprognostic (2.14e-2)" "unprognostic (1.02e-1)" "unprognostic (1.59e-1)" "unprognostic (3.49e-2)" "unprognostic (1.31e-2)" "unprognostic (1.32e-3)" "unprognostic (1.68e-3)" "unprognostic (4.63e-3)" "unprognostic (1.76e-1)" "unprognostic (1.59e-1)" "unprognostic (1.62e-3)" "unprognostic (2.64e-2)" "unprognostic (2.33e-2)" "unprognostic (9.17e-3)" "unprognostic (1.17e-1)" "unprognostic (9.59e-2)" "unprognostic (8.17e-3)" "unprognostic (2.19e-1)" "unprognostic (3.54e-3)" "unprognostic (3.88e-1)" "unprognostic (2.01e-3)" "unprognostic (3.03e-1)" "unprognostic (5.87e-1)" "unprognostic (3.19e-1)" "unprognostic (5.77e-2)" "unprognostic (2.64e-1)" "unprognostic (1.37e-2)" "unprognostic (5.60e-2)" "unprognostic (7.21e-2)" "unprognostic (8.36e-2)" "unprognostic (8.28e-2)" RBL1 "cp107, p107, PRB1" ENSG00000080839 "RB transcriptional corepressor like 1" P28749 20 36996349-37095997 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 13.7" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 145.2;Erythrocyte progenitors: 185.4;Megakaryocyte progenitors: 111.7;Monocyte progenitors: 169.3;Myonuclei: 156.9;Neutrophil progenitors: 141.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Testis - Spermatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA054962, HPA056525" Enhanced Enhanced Nucleoplasm NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 25: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 27: Non-specific - Cell proliferation" 43 Nucleoplasm "HPA054962: , HPA056525: " "unprognostic (8.24e-2)" "unprognostic (9.20e-2)" "unprognostic (1.02e-1)" "unprognostic (1.53e-1)" "unprognostic (1.17e-1)" "unprognostic (2.83e-2)" "unprognostic (3.06e-1)" "unprognostic (3.14e-1)" "unprognostic (5.40e-2)" "potential prognostic unfavorable (1.57e-4)" "unprognostic (1.54e-3)" "unprognostic (5.15e-2)" "unprognostic (1.35e-2)" "potential prognostic unfavorable (2.40e-4)" "unprognostic (2.68e-3)" "unprognostic (1.61e-2)" "unprognostic (1.40e-3)" "unprognostic (1.29e-1)" "unprognostic (2.04e-1)" "unprognostic (2.92e-1)" "unprognostic (1.61e-1)" "unprognostic (1.80e-2)" "potential prognostic unfavorable (3.06e-4)" "unprognostic (3.86e-2)" "unprognostic (1.08e-2)" "unprognostic (1.66e-2)" "unprognostic (3.50e-3)" "unprognostic (1.29e-1)" "unprognostic (3.93e-1)" "unprognostic (1.03e-1)" "unprognostic (7.77e-3)" RBL2 "p130, Rb2" ENSG00000103479 "RB transcriptional corepressor like 2" Q08999 16 53433977-53491648 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Intellectual disability, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 539.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016547, HPA019703" Supported Supported "Nucleoplasm,Nucleoli rim,Mitotic chromosome,Cytosol" Yes No "Cluster 27: T-cells - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 53 "Nucleoplasm, Nucleoli rim, Mitotic chromosome" Cytosol "CAB016547: , HPA019703: " "unprognostic (1.74e-1)" "unprognostic (9.35e-2)" "unprognostic (2.19e-1)" "unprognostic (1.15e-2)" "unprognostic (1.09e-1)" "unprognostic (2.85e-1)" "unprognostic (1.11e-1)" "unprognostic (2.94e-2)" "unprognostic (8.85e-2)" "unprognostic (1.77e-1)" "potential prognostic favorable (1.08e-7)" "unprognostic (1.67e-2)" "unprognostic (3.84e-2)" "unprognostic (1.53e-1)" "potential prognostic favorable (2.49e-4)" "unprognostic (8.89e-2)" "unprognostic (1.59e-1)" "unprognostic (8.33e-2)" "unprognostic (1.19e-1)" "unprognostic (2.89e-2)" "unprognostic (4.81e-2)" "unprognostic (8.60e-2)" "unprognostic (3.07e-2)" "unprognostic (1.46e-1)" "potential prognostic favorable (7.48e-4)" "unprognostic (1.14e-1)" "unprognostic (3.22e-1)" "unprognostic (1.01e-1)" "unprognostic (9.21e-2)" "unprognostic (9.33e-3)" "unprognostic (3.77e-1)" RBM10 "DXS8237E, GPATC9, GPATCH9, KIAA0122, S1-1, ZRANB5" ENSG00000182872 "RNA binding motif protein 10" P98175 X 47145221-47186813 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034972, HPA057372" Approved Enhanced "Nuclear speckles" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 36: Non-specific - mRNA processing" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 96 "Nuclear speckles" "HPA034972: , HPA057372: " "unprognostic (2.26e-1)" "unprognostic (1.17e-1)" "unprognostic (1.24e-1)" "unprognostic (2.67e-1)" "unprognostic (2.21e-1)" "unprognostic (1.20e-1)" "unprognostic (4.20e-1)" "potential prognostic favorable (7.92e-4)" "unprognostic (3.68e-2)" "unprognostic (7.27e-2)" "unprognostic (1.05e-1)" "unprognostic (2.21e-1)" "unprognostic (9.12e-3)" "potential prognostic unfavorable (1.60e-4)" "unprognostic (3.84e-2)" "unprognostic (6.83e-2)" "unprognostic (2.37e-3)" "unprognostic (1.81e-1)" "unprognostic (4.57e-2)" "unprognostic (1.57e-1)" "unprognostic (1.74e-3)" "unprognostic (1.39e-3)" "unprognostic (4.36e-2)" "unprognostic (1.12e-1)" "unprognostic (1.06e-1)" "unprognostic (5.63e-2)" "unprognostic (2.94e-2)" "unprognostic (7.91e-2)" "unprognostic (4.22e-2)" "unprognostic (1.37e-1)" "unprognostic (1.05e-1)" RBM11 ENSG00000185272 "RNA binding motif protein 11" P57052 21 14216130-14228372 "Predicted intracellular proteins" "Differentiation, mRNA processing, mRNA splicing" "Developmental protein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "epididymis: 42.7" "Cell type enriched" "Detected in many" 5 "Epididymal principal cells: 425.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "naive CD4 T-cell: 1.2" "Lineage enriched" "Detected in single" 10 "T-cells: 1.2" "Cancer enriched" "Detected in some" 24 "Bone cancer: 24.3" "Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045885 Supported Nucleoplasm NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 22: Epididymis - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 43 Nucleoplasm "HPA045885: " "unprognostic (8.05e-2)" "unprognostic (9.38e-2)" "unprognostic (3.53e-1)" "unprognostic (9.01e-2)" "unprognostic (8.65e-2)" "unprognostic (2.43e-1)" "unprognostic (3.13e-2)" "unprognostic (1.16e-1)" "unprognostic (2.01e-1)" RBM12 "HRIHFB2091, KIAA0765, SWAN" ENSG00000244462 "RNA binding motif protein 12" Q9NTZ6 20 35648925-35664956 "Disease related genes, Human disease related genes, Predicted intracellular proteins" RNA-binding "Disease variant, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043258, HPA043621" Enhanced Enhanced Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 17: Non-specific - RNA processing" 24 Nucleoplasm "HPA043258: , HPA043621: " "unprognostic (8.92e-2)" "unprognostic (1.12e-1)" "unprognostic (3.33e-2)" "unprognostic (8.75e-3)" "unprognostic (1.17e-1)" "unprognostic (8.93e-2)" "unprognostic (1.19e-1)" "unprognostic (1.25e-2)" "unprognostic (3.28e-1)" "potential prognostic unfavorable (4.39e-4)" "validated prognostic favorable (1.77e-5)" "validated prognostic favorable (4.75e-4)" "unprognostic (3.32e-1)" "unprognostic (1.84e-3)" "unprognostic (1.70e-3)" "unprognostic (4.22e-2)" "unprognostic (2.50e-3)" "unprognostic (4.22e-1)" "unprognostic (2.51e-2)" "unprognostic (3.34e-2)" "unprognostic (3.02e-3)" "unprognostic (1.57e-3)" "unprognostic (8.39e-3)" "unprognostic (5.79e-2)" "unprognostic (3.04e-3)" "unprognostic (1.12e-2)" "unprognostic (1.34e-1)" "unprognostic (1.10e-1)" "unprognostic (1.72e-1)" "unprognostic (2.10e-2)" "unprognostic (1.83e-1)" RBM12B ENSG00000183808 "RNA binding motif protein 12B" Q8IXT5 8 93728155-93741017 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024398, HPA053050" Uncertain Approved Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 6 Nucleoplasm "HPA024398: , HPA053050: " "unprognostic (6.30e-2)" "unprognostic (5.31e-2)" "unprognostic (2.07e-1)" "unprognostic (1.00e-2)" "unprognostic (3.69e-2)" "unprognostic (2.60e-2)" "unprognostic (2.71e-1)" "unprognostic (1.18e-2)" "unprognostic (1.14e-1)" "unprognostic (1.18e-3)" "unprognostic (1.02e-2)" "unprognostic (2.93e-2)" "unprognostic (5.41e-3)" "unprognostic (1.29e-3)" "unprognostic (1.10e-1)" "unprognostic (9.52e-2)" "unprognostic (2.34e-3)" "unprognostic (1.86e-1)" "unprognostic (2.23e-2)" "unprognostic (2.05e-2)" "unprognostic (6.52e-2)" "unprognostic (5.47e-2)" "unprognostic (3.72e-3)" "unprognostic (3.90e-2)" "unprognostic (1.38e-2)" "unprognostic (1.05e-1)" "unprognostic (1.09e-2)" "unprognostic (7.47e-2)" "unprognostic (3.56e-1)" "unprognostic (3.89e-3)" "unprognostic (1.11e-1)" RBM14 "COAA, DKFZp779J0927, SIP, SYTIP1" ENSG00000239306 "RNA binding motif protein 14" Q96PK6 11 66616626-66629934 "Essential proteins, Predicted intracellular proteins" "Immunity, Innate immunity, Transcription, Transcription regulation" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 7 "Astrocytes: 36.4;Bergmann glia: 45.2;Brain excitatory neurons: 33.5;Brain inhibitory neurons: 35.4;Choroid plexus epithelial cells: 95.6;Ependymal cells: 48.5;Microglia: 59.9;Oligodendrocyte progenitor cells: 34.1;Oligodendrocytes: 34.8;Other brain neurons: 27.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006628 Supported Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA 5400 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 64: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 22: Non-specific - Basic cellular functions" 187 Nucleoplasm "Nuclear speckles, Cytosol" "HPA006628: " "unprognostic (1.15e-1)" "unprognostic (9.03e-2)" "unprognostic (1.56e-1)" "unprognostic (1.23e-1)" "unprognostic (5.88e-2)" "unprognostic (5.61e-2)" "unprognostic (3.35e-1)" "unprognostic (7.43e-2)" "unprognostic (4.91e-2)" "unprognostic (9.02e-2)" "unprognostic (1.37e-3)" "unprognostic (1.24e-2)" "unprognostic (1.30e-1)" "potential prognostic unfavorable (1.13e-5)" "unprognostic (3.39e-2)" "unprognostic (6.75e-2)" "unprognostic (3.92e-3)" "unprognostic (9.45e-2)" "unprognostic (6.41e-2)" "unprognostic (9.93e-2)" "unprognostic (5.28e-2)" "potential prognostic favorable (6.34e-4)" "unprognostic (6.81e-3)" "unprognostic (5.76e-2)" "unprognostic (6.91e-3)" "unprognostic (1.35e-1)" "unprognostic (5.55e-2)" "unprognostic (1.06e-1)" "unprognostic (1.21e-1)" "unprognostic (1.58e-1)" "unprognostic (2.97e-2)" RBM14-RBM4 ENSG00000248643 "RBM14-RBM4 readthrough" 11 66616626-66646469 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" HPA047849 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 15: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" Nucleoplasm Cytosol "HPA047849: " "unprognostic (2.39e-1)" "unprognostic (2.81e-2)" "unprognostic (7.51e-2)" "unprognostic (5.50e-3)" "unprognostic (1.32e-1)" "unprognostic (3.01e-2)" "unprognostic (6.69e-2)" "unprognostic (1.16e-1)" "unprognostic (2.75e-1)" "unprognostic (7.16e-2)" "unprognostic (1.01e-1)" "unprognostic (9.28e-3)" "unprognostic (1.01e-1)" "unprognostic (3.07e-2)" "unprognostic (1.02e-1)" "unprognostic (3.73e-3)" "unprognostic (1.09e-1)" "unprognostic (8.67e-3)" "unprognostic (5.06e-2)" "unprognostic (2.45e-2)" "unprognostic (6.91e-2)" "unprognostic (2.38e-1)" "unprognostic (2.44e-1)" "unprognostic (4.58e-2)" "unprognostic (9.05e-2)" RBM15 "OTT, OTT1" ENSG00000162775 "RNA binding motif protein 15" Q96T37 1 110338506-110346681 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" RNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 42.3" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Macrophages, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015201, HPA019824, HPA049642" Supported Enhanced Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 15: Non-specific - Transcription" "Cluster 59: Leukemia - T-cell receptor" "Cluster 27: Non-specific - Cell proliferation" 40 Nucleoplasm "CAB015201: , HPA019824: , HPA049642: " "unprognostic (1.04e-1)" "unprognostic (3.13e-1)" "unprognostic (3.80e-1)" "unprognostic (4.31e-3)" "unprognostic (1.00e-1)" "unprognostic (2.13e-1)" "unprognostic (2.19e-1)" "unprognostic (3.33e-3)" "unprognostic (4.36e-2)" "unprognostic (4.90e-3)" "potential prognostic favorable (2.48e-4)" "unprognostic (6.99e-3)" "unprognostic (3.27e-1)" "potential prognostic unfavorable (2.66e-4)" "unprognostic (1.86e-2)" "potential prognostic unfavorable (3.65e-4)" "unprognostic (9.16e-2)" "unprognostic (1.42e-2)" "unprognostic (9.85e-3)" "unprognostic (3.93e-1)" "unprognostic (2.32e-1)" "unprognostic (4.36e-2)" "unprognostic (1.55e-2)" "unprognostic (3.89e-2)" "unprognostic (1.88e-2)" "unprognostic (3.58e-2)" "unprognostic (6.28e-2)" "unprognostic (1.21e-2)" "unprognostic (1.78e-1)" "unprognostic (2.06e-3)" "unprognostic (1.36e-1)" RBM15B "HUMAGCGB, OTT3" ENSG00000259956 "RNA binding motif protein 15B" Q8NDT2 3 51391285-51397908 "Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing, Transcription, Transcription regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036645, HPA058136" Approved Enhanced Nucleoplasm NA NA 52000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 54: Non-specific - Ribosome" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 17: Non-specific - RNA processing" 11 Nucleoplasm "HPA036645: , HPA058136: " "unprognostic (2.92e-2)" "unprognostic (3.13e-2)" "unprognostic (2.26e-1)" "unprognostic (3.15e-2)" "unprognostic (6.99e-2)" "unprognostic (1.52e-1)" "unprognostic (5.09e-1)" "unprognostic (1.90e-2)" "unprognostic (1.50e-2)" "potential prognostic favorable (6.06e-4)" "unprognostic (5.43e-2)" "unprognostic (7.63e-3)" "validated prognostic unfavorable (8.82e-4)" "validated prognostic unfavorable (8.56e-4)" "unprognostic (4.48e-2)" "unprognostic (1.24e-3)" "unprognostic (4.19e-1)" "unprognostic (4.37e-3)" "unprognostic (3.54e-1)" "unprognostic (2.10e-1)" "unprognostic (8.55e-2)" "unprognostic (3.89e-2)" "unprognostic (1.41e-2)" "unprognostic (2.02e-1)" "unprognostic (3.45e-1)" "unprognostic (2.21e-1)" "unprognostic (1.55e-1)" "unprognostic (6.76e-2)" RBM17 "MGC14439, SPF45" ENSG00000134453 "RNA binding motif protein 17" Q96I25 10 6089034-6117457 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early primary spermatocytes: 330.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037477, HPA037478" Supported Supported Nucleoplasm NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 117 Nucleoplasm "HPA037477: , HPA037478: " "unprognostic (2.60e-1)" "unprognostic (2.38e-2)" "unprognostic (3.10e-3)" "unprognostic (8.27e-2)" "unprognostic (1.07e-1)" "unprognostic (1.16e-1)" "unprognostic (7.70e-2)" "potential prognostic favorable (1.57e-5)" "unprognostic (5.37e-2)" "unprognostic (1.14e-2)" "unprognostic (2.05e-2)" "unprognostic (2.26e-2)" "potential prognostic unfavorable (1.62e-4)" "validated prognostic unfavorable (8.41e-8)" "validated prognostic unfavorable (2.12e-4)" "unprognostic (4.27e-2)" "potential prognostic unfavorable (6.42e-5)" "unprognostic (1.91e-1)" "unprognostic (7.43e-3)" "unprognostic (6.53e-2)" "unprognostic (4.31e-1)" "unprognostic (3.39e-2)" "unprognostic (1.29e-3)" "unprognostic (7.64e-2)" "unprognostic (6.93e-2)" "unprognostic (2.64e-1)" "unprognostic (9.64e-2)" "unprognostic (7.97e-2)" "unprognostic (3.02e-1)" "unprognostic (1.32e-1)" "unprognostic (3.42e-1)" RBM18 MGC2734 ENSG00000119446 "RNA binding motif protein 18" Q96H35 9 122237622-122264840 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 107.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057281, HPA077955" Uncertain Enhanced "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes No "Cluster 45: Eosinophils - Unknown function" "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 27: Non-specific - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 2 Nucleoplasm "Cytokinetic bridge, Cytosol" "HPA057281: , HPA077955: " "unprognostic (2.65e-2)" "unprognostic (1.01e-2)" "unprognostic (1.47e-2)" "unprognostic (1.95e-1)" "unprognostic (3.04e-2)" "potential prognostic unfavorable (7.94e-5)" "unprognostic (1.36e-1)" "unprognostic (8.53e-2)" "unprognostic (1.08e-2)" "unprognostic (1.92e-1)" "potential prognostic favorable (1.26e-7)" "unprognostic (1.40e-3)" "unprognostic (1.61e-1)" "unprognostic (4.44e-2)" "unprognostic (1.02e-1)" "unprognostic (2.67e-2)" "unprognostic (3.82e-1)" "unprognostic (2.34e-3)" "unprognostic (8.84e-2)" "unprognostic (1.25e-1)" "potential prognostic unfavorable (6.37e-5)" "unprognostic (1.64e-1)" "unprognostic (8.48e-2)" "unprognostic (1.18e-1)" "unprognostic (2.70e-1)" "unprognostic (1.08e-1)" "unprognostic (1.38e-2)" "unprognostic (1.55e-1)" "unprognostic (1.75e-1)" "unprognostic (9.75e-2)" "unprognostic (1.13e-1)" RBM19 "DKFZp586F1023, KIAA0682, Mrd1" ENSG00000122965 "RNA binding motif protein 19" Q9Y4C8 12 113816738-113966325 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Developmental protein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038860, HPA058732" Supported Supported Nucleoli NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 38: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 50 Nucleoli "HPA038860: , HPA058732: " "unprognostic (9.05e-3)" "unprognostic (3.97e-1)" "unprognostic (3.71e-1)" "unprognostic (2.80e-1)" "unprognostic (2.60e-1)" "unprognostic (7.94e-2)" "unprognostic (1.35e-1)" "unprognostic (3.20e-3)" "unprognostic (1.91e-1)" "unprognostic (1.06e-2)" "unprognostic (5.35e-2)" "unprognostic (8.30e-2)" "unprognostic (9.09e-2)" "potential prognostic unfavorable (6.39e-6)" "unprognostic (1.26e-2)" "unprognostic (5.49e-3)" "unprognostic (8.14e-2)" "unprognostic (1.14e-1)" "unprognostic (6.52e-2)" "unprognostic (6.03e-3)" "unprognostic (1.04e-1)" "unprognostic (2.07e-1)" "potential prognostic unfavorable (4.73e-4)" "unprognostic (9.30e-2)" "unprognostic (4.53e-2)" "potential prognostic favorable (1.78e-5)" "unprognostic (3.01e-1)" "unprognostic (1.57e-1)" "unprognostic (2.10e-1)" "unprognostic (1.19e-1)" "unprognostic (4.82e-3)" RBM20 ENSG00000203867 "RNA binding motif protein 20" Q5T481 10 110644336-110839468 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 38.2;pancreas: 18.7" "Cell type enriched" "Detected in many" 6 "Cardiomyocytes: 2187.7" "Cell type enhanced" "Detected in many" "endothelial cell: 277.4;medium spiny neuron: 156.0" "Cancer enhanced" "Detected in some" "Kidney Renal Papillary Cell Carcinoma (TCGA): 2.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 10.6" "Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA035806, HPA070358" Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Cytokinetic bridge" Yes No "Cluster 35: Non-specific - Mixed function" "Cluster 33: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 2 "Nucleoplasm, Golgi apparatus" "Nucleoli, Cytokinetic bridge" "HPA035806: , HPA070358: " "unprognostic (2.15e-1)" "unprognostic (8.60e-3)" "potential prognostic unfavorable (5.50e-4)" "potential prognostic favorable (4.49e-4)" "unprognostic (2.29e-1)" "unprognostic (1.53e-1)" "unprognostic (4.50e-2)" "unprognostic (3.14e-2)" RBM22 "Cwc2, FLJ10290, fSAP47, ZC3H16" ENSG00000086589 "RNA binding motif protein 22" Q9NW64 5 150690792-150701077 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 127.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001634 Supported Enhanced Nucleoplasm NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 20: Non-specific - Transcription regulation" 44 Nucleoplasm "HPA001634: " "unprognostic (8.59e-2)" "unprognostic (1.66e-1)" "unprognostic (6.98e-2)" "unprognostic (2.70e-1)" "unprognostic (1.60e-1)" "unprognostic (1.14e-1)" "unprognostic (1.74e-1)" "unprognostic (1.86e-1)" "unprognostic (8.48e-2)" "unprognostic (6.61e-3)" "validated prognostic favorable (7.99e-8)" "validated prognostic favorable (8.64e-5)" "unprognostic (1.71e-2)" "unprognostic (1.29e-3)" "unprognostic (3.23e-2)" "unprognostic (5.53e-2)" "unprognostic (2.28e-2)" "unprognostic (6.93e-2)" "unprognostic (8.28e-2)" "unprognostic (1.22e-2)" "unprognostic (2.03e-2)" "unprognostic (3.74e-2)" "unprognostic (2.65e-2)" "unprognostic (4.12e-2)" "unprognostic (1.20e-2)" "unprognostic (2.10e-1)" "unprognostic (7.13e-2)" "unprognostic (2.29e-1)" "unprognostic (2.10e-1)" "unprognostic (9.22e-3)" "unprognostic (4.38e-2)" RBM23 "CAPERbeta, FLJ10482, RNPC4" ENSG00000100461 "RNA binding motif protein 23" Q86U06 14 22893204-22919182 "Predicted intracellular proteins" "mRNA processing, mRNA splicing, Transcription, Transcription regulation" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 381.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" HPA004144 Uncertain Approved "Nucleoplasm,Intermediate filaments" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 61: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 14 "Intermediate filaments" Nucleoplasm "HPA004144: " "unprognostic (1.03e-1)" "unprognostic (1.55e-1)" "unprognostic (1.32e-1)" "unprognostic (1.76e-1)" "unprognostic (1.03e-1)" "unprognostic (1.56e-1)" "unprognostic (1.15e-1)" "potential prognostic favorable (8.44e-6)" "unprognostic (1.67e-1)" "potential prognostic unfavorable (3.72e-4)" "validated prognostic favorable (5.15e-7)" "validated prognostic favorable (2.42e-5)" "unprognostic (1.90e-3)" "unprognostic (9.91e-2)" "unprognostic (6.44e-2)" "unprognostic (3.34e-1)" "unprognostic (2.07e-1)" "unprognostic (2.01e-1)" "unprognostic (1.77e-2)" "unprognostic (2.81e-2)" "unprognostic (2.21e-1)" "unprognostic (6.49e-3)" "unprognostic (1.46e-1)" "unprognostic (2.27e-1)" "unprognostic (2.48e-1)" "unprognostic (6.86e-2)" "unprognostic (1.09e-1)" "unprognostic (1.35e-1)" "unprognostic (3.49e-1)" "unprognostic (1.80e-1)" "unprognostic (2.08e-1)" RBM24 "dJ259A10.1, FLJ30829, RNPC6" ENSG00000112183 "RNA binding motif protein 24" Q9BX46 6 17281361-17293871 "Predicted intracellular proteins" "Differentiation, mRNA processing, mRNA splicing, Translation regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "heart muscle: 132.9;skeletal muscle: 293.2;tongue: 98.7" "Cell type enriched" "Detected in many" 7 "Myonuclei: 1607.1" "Cell type enhanced" "Detected in many" "vascular associated smooth muscle cell: 111.7" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 15.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Adrenal gland - Smooth muscle cells, Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA066927, HPA067231" Enhanced Enhanced Nucleoplasm,Cytosol NA NA "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 33: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 4 Nucleoplasm Cytosol "HPA066927: , HPA067231: " "unprognostic (1.71e-1)" "unprognostic (1.01e-2)" "unprognostic (2.24e-1)" "unprognostic (1.35e-1)" "unprognostic (1.37e-1)" "unprognostic (7.93e-3)" "potential prognostic unfavorable (3.90e-4)" "potential prognostic favorable (9.93e-4)" "unprognostic (2.72e-2)" "unprognostic (9.22e-2)" "unprognostic (2.01e-2)" "potential prognostic unfavorable (2.25e-4)" "unprognostic (1.21e-2)" "unprognostic (7.07e-2)" "unprognostic (3.39e-1)" "unprognostic (1.27e-1)" "unprognostic (1.16e-1)" "unprognostic (1.77e-1)" "unprognostic (7.24e-3)" "unprognostic (1.65e-2)" "unprognostic (6.99e-2)" RBM25 "fSAP94, NET52, RNPC7, S164, Snu71" ENSG00000119707 "RNA binding motif protein 25" P49756 14 73058532-73123899 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003025, HPA070713" Supported Enhanced "Nuclear speckles" NA NA 25000 "Cluster 22: Eosinophils - Transcription" "Cluster 49: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 17: Non-specific - RNA processing" 72 "Nuclear speckles" "HPA003025: , HPA070713: " "unprognostic (2.17e-2)" "unprognostic (3.14e-1)" "unprognostic (3.30e-1)" "unprognostic (2.97e-1)" "unprognostic (3.14e-1)" "unprognostic (7.94e-2)" "unprognostic (1.47e-2)" "unprognostic (9.73e-3)" "unprognostic (6.06e-2)" "unprognostic (5.07e-3)" "validated prognostic favorable (1.98e-5)" "validated prognostic favorable (7.55e-4)" "unprognostic (2.74e-1)" "unprognostic (3.52e-3)" "unprognostic (1.99e-2)" "unprognostic (6.91e-2)" "unprognostic (7.60e-2)" "unprognostic (1.71e-1)" "potential prognostic favorable (9.28e-4)" "unprognostic (1.42e-1)" "unprognostic (1.98e-1)" "unprognostic (6.91e-3)" "unprognostic (3.47e-3)" "unprognostic (2.39e-2)" "unprognostic (3.85e-2)" "unprognostic (1.22e-1)" "unprognostic (2.74e-1)" "unprognostic (8.47e-2)" "unprognostic (1.62e-1)" "unprognostic (2.68e-1)" "unprognostic (5.41e-2)" RBM26 "ARRS2, C13orf10, FLJ20957, PPP1R132, PRO1777, SE70-2, ZC3H17" ENSG00000139746 "RNA binding motif protein 26" Q5T8P6 13 79311824-79406477 "Plasma proteins, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040252 Approved Approved "Nuclear speckles" NA NA "Cluster 32: Basophils - Transcription" "Cluster 39: Testis - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 19: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 17 "Nuclear speckles" "HPA040252: " "unprognostic (4.58e-2)" "unprognostic (1.12e-1)" "unprognostic (1.03e-1)" "unprognostic (8.83e-2)" "unprognostic (1.46e-1)" "unprognostic (3.25e-1)" "unprognostic (3.11e-2)" "unprognostic (1.02e-2)" "unprognostic (2.47e-1)" "unprognostic (1.64e-2)" "unprognostic (1.96e-1)" "unprognostic (2.04e-2)" "unprognostic (1.82e-1)" "unprognostic (4.31e-3)" "unprognostic (1.67e-1)" "unprognostic (9.55e-2)" "unprognostic (2.51e-2)" "unprognostic (2.30e-1)" "unprognostic (1.23e-2)" "unprognostic (2.38e-1)" "unprognostic (2.24e-2)" "unprognostic (4.59e-2)" "unprognostic (1.15e-2)" "unprognostic (2.38e-2)" "unprognostic (3.64e-3)" "unprognostic (2.12e-2)" "unprognostic (9.62e-3)" "unprognostic (1.23e-1)" "unprognostic (2.52e-2)" "unprognostic (1.29e-1)" "unprognostic (6.88e-2)" RBM27 "ARRS1, KIAA1311, Psc1, ZC3H20" ENSG00000091009 "RNA binding motif protein 27" Q9P2N5 5 146203605-146289223 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 9.5;Megakaryocyte progenitors: 7.9;Megakaryocyte-Erythroid progenitors: 7.8;Retinal pigment epithelial cells: 8.5" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035944, HPA036422" Approved Approved "Nuclear speckles" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 17: Non-specific - RNA processing" 13 "Nuclear speckles" "HPA035944: , HPA036422: " "unprognostic (4.27e-2)" "unprognostic (3.38e-2)" "unprognostic (9.20e-2)" "unprognostic (2.46e-3)" "unprognostic (2.75e-2)" "unprognostic (1.97e-1)" "unprognostic (1.10e-1)" "unprognostic (2.34e-1)" "unprognostic (6.05e-3)" "unprognostic (4.29e-3)" "potential prognostic favorable (8.75e-7)" "unprognostic (5.25e-3)" "unprognostic (1.11e-1)" "unprognostic (1.28e-2)" "unprognostic (1.29e-1)" "unprognostic (5.06e-3)" "unprognostic (1.15e-1)" "unprognostic (1.62e-1)" "unprognostic (3.14e-1)" "unprognostic (2.47e-2)" "unprognostic (6.13e-3)" "unprognostic (2.88e-3)" "unprognostic (2.91e-2)" "unprognostic (5.38e-2)" "unprognostic (5.57e-2)" "unprognostic (9.05e-2)" "unprognostic (2.93e-1)" "unprognostic (4.08e-2)" "unprognostic (1.67e-1)" "unprognostic (6.13e-3)" "unprognostic (2.57e-2)" RBM28 FLJ10377 ENSG00000106344 "RNA binding motif protein 28" Q9NW13 7 128297685-128343908 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Disease variant, Hypotrichosis, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 147.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019058, HPA026672, HPA031519" Enhanced Supported Nucleoli NA No "Cluster 14: Non-specific - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 39: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 86 Nucleoli "HPA019058: , HPA026672: , HPA031519: " "unprognostic (4.28e-3)" "unprognostic (6.87e-2)" "unprognostic (1.33e-1)" "unprognostic (1.76e-1)" "unprognostic (3.27e-1)" "unprognostic (2.64e-1)" "unprognostic (6.71e-2)" "unprognostic (1.83e-2)" "unprognostic (1.58e-1)" "potential prognostic unfavorable (8.41e-4)" "unprognostic (5.59e-2)" "unprognostic (2.21e-1)" "unprognostic (9.42e-3)" "potential prognostic unfavorable (8.97e-6)" "unprognostic (9.95e-3)" "unprognostic (2.27e-3)" "unprognostic (3.59e-3)" "unprognostic (3.04e-1)" "unprognostic (2.20e-2)" "unprognostic (1.64e-1)" "unprognostic (1.08e-1)" "unprognostic (8.75e-3)" "unprognostic (1.60e-2)" "unprognostic (8.93e-2)" "unprognostic (3.94e-2)" "unprognostic (9.74e-2)" "unprognostic (6.86e-3)" "unprognostic (1.51e-2)" "unprognostic (1.20e-1)" "unprognostic (3.96e-2)" "unprognostic (7.13e-3)" RBM3 IS1-RNPL ENSG00000102317 "RNA binding motif protein 3" P98179 X 48574449-48581162 "Predicted intracellular proteins" "Stress response" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 873.2;Megakaryocytes: 840.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA003624, CAB062559" Enhanced Enhanced Nucleoplasm NA NA 46000 "Cluster 13: Non-specific - Mitochondria" "Cluster 15: Bone marrow - Innate immune response" "Cluster 30: White matter - Myelination" "Cluster 36: Non-specific - mRNA processing" "Cluster 97: Non-specific - Cellular respiration" 43 Nucleoplasm "CAB062559: , HPA003624: " "unprognostic (1.48e-2)" "unprognostic (1.22e-2)" "unprognostic (8.46e-2)" "unprognostic (2.34e-2)" "unprognostic (2.28e-3)" "unprognostic (5.72e-3)" "unprognostic (7.98e-2)" "unprognostic (1.18e-2)" "unprognostic (5.04e-2)" "unprognostic (4.57e-3)" "potential prognostic favorable (1.41e-10)" "unprognostic (1.34e-1)" "unprognostic (5.29e-2)" "unprognostic (8.10e-3)" "unprognostic (3.24e-2)" "unprognostic (2.47e-1)" "unprognostic (2.93e-1)" "unprognostic (3.35e-1)" "unprognostic (3.26e-1)" "unprognostic (4.80e-2)" "unprognostic (9.90e-2)" "unprognostic (2.21e-2)" "unprognostic (2.03e-1)" "unprognostic (2.25e-2)" "unprognostic (1.89e-2)" "unprognostic (5.23e-3)" "unprognostic (5.21e-2)" "unprognostic (2.09e-1)" "unprognostic (4.59e-2)" "unprognostic (4.38e-3)" "unprognostic (5.73e-3)" RBM33 "DKFZp434D1319, DKFZp686F102, MGC20460, PRR8" ENSG00000184863 "RNA binding motif protein 33" Q96EV2 7 155644451-155781485 "Predicted intracellular proteins" "mRNA transport, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019232, HPA021497, HPA021768" Approved Approved Nucleoplasm NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 39: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 36 Nucleoplasm "HPA019232: , HPA021497: , HPA021768: " "unprognostic (2.70e-2)" "unprognostic (8.79e-2)" "unprognostic (4.55e-2)" "unprognostic (4.13e-3)" "unprognostic (9.65e-2)" "potential prognostic unfavorable (4.22e-4)" "unprognostic (1.58e-1)" "unprognostic (1.00e-2)" "unprognostic (1.08e-2)" "unprognostic (8.95e-3)" "potential prognostic unfavorable (7.32e-4)" "unprognostic (1.89e-1)" "unprognostic (3.59e-1)" "unprognostic (1.12e-3)" "unprognostic (1.32e-1)" "unprognostic (2.08e-1)" "unprognostic (8.93e-2)" "unprognostic (1.07e-1)" "unprognostic (1.69e-1)" "unprognostic (1.27e-1)" "unprognostic (4.19e-2)" "unprognostic (5.10e-3)" "unprognostic (1.25e-2)" "unprognostic (1.85e-1)" "unprognostic (1.74e-2)" "unprognostic (2.46e-3)" "unprognostic (5.35e-3)" "unprognostic (2.01e-1)" "unprognostic (3.77e-1)" "unprognostic (1.70e-2)" "unprognostic (4.09e-2)" RBM34 KIAA0117 ENSG00000188739 "RNA binding motif protein 34" P42696 1 235131183-235161283 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 15.5;Bergmann glia: 15.7;Brain excitatory neurons: 17.5;Brain inhibitory neurons: 18.4;Choroid plexus epithelial cells: 37.7;Ependymal cells: 14.2;Microglia: 37.0;Oligodendrocyte progenitor cells: 18.7;Oligodendrocytes: 20.8;Other brain neurons: 18.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028606 Approved Supported "Nucleoplasm,Nucleoli,Mitotic chromosome" Yes No "Cluster 5: Non-specific - Cell proliferation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 22: Non-specific - Basic cellular functions" 84 Nucleoli "Nucleoplasm, Mitotic chromosome" "HPA028606: " "unprognostic (1.28e-2)" "unprognostic (3.34e-2)" "unprognostic (1.65e-1)" "unprognostic (4.93e-3)" "unprognostic (3.14e-1)" "unprognostic (2.80e-1)" "unprognostic (1.41e-1)" "unprognostic (8.22e-3)" "unprognostic (8.72e-3)" "unprognostic (1.86e-3)" "unprognostic (9.03e-2)" "unprognostic (1.60e-1)" "unprognostic (1.64e-3)" "unprognostic (2.52e-3)" "unprognostic (9.46e-2)" "unprognostic (2.94e-2)" "unprognostic (1.41e-3)" "unprognostic (2.41e-2)" "unprognostic (2.43e-2)" "unprognostic (1.81e-2)" "unprognostic (9.20e-3)" "unprognostic (4.94e-2)" "unprognostic (5.65e-3)" "unprognostic (5.96e-2)" "unprognostic (1.56e-1)" "unprognostic (5.29e-2)" "unprognostic (2.88e-2)" "unprognostic (1.62e-1)" "unprognostic (2.98e-2)" "unprognostic (7.44e-2)" "unprognostic (1.72e-1)" RBM38 "dJ800J21.2, HSRNASEB, RNPC1, seb4B, SEB4D" ENSG00000132819 "RNA binding motif protein 38" Q9H0Z9 20 57391396-57409333 "Predicted intracellular proteins" "Cell cycle, Differentiation, Host-virus interaction, mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 251.7;skeletal muscle: 261.1" "Cell type enhanced" "Detected in many" "Erythrocytes: 426.9;Fallopian tube ciliated cells: 117.1;Megakaryocytes: 234.9;pDCs: 138.8;Platelets: 330.8" "Cell type enhanced" "Detected in many" "ependymal cell: 42.7;leukocyte: 40.4" "Cancer enhanced" "Detected in all" "Ovary Serous Cystadenocarcinoma (TCGA): 167.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "lymphoma: 160.0" "Breast - Breast myoepithelial cells, Prostate - Smooth muscle cells, Stomach - Fibroblasts, Testis - Sertoli cells, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB017036 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 8 "Nucleoplasm, Cytosol" "CAB017036: " "unprognostic (4.90e-2)" "unprognostic (3.43e-1)" "unprognostic (6.97e-3)" "unprognostic (3.62e-1)" "unprognostic (1.92e-1)" "unprognostic (8.45e-2)" "unprognostic (6.71e-2)" "unprognostic (1.62e-1)" "unprognostic (1.52e-3)" "unprognostic (1.50e-1)" "unprognostic (1.73e-3)" "unprognostic (1.30e-2)" "unprognostic (7.43e-2)" "unprognostic (1.84e-2)" "unprognostic (2.76e-1)" "unprognostic (8.77e-3)" "unprognostic (1.83e-1)" "unprognostic (1.95e-3)" "unprognostic (9.07e-2)" "unprognostic (2.14e-1)" "unprognostic (1.62e-1)" "unprognostic (1.96e-1)" "unprognostic (8.45e-2)" "unprognostic (4.34e-1)" "unprognostic (5.54e-2)" "unprognostic (9.43e-3)" "unprognostic (3.15e-3)" "unprognostic (5.73e-2)" "unprognostic (1.19e-1)" "unprognostic (1.26e-2)" "unprognostic (1.15e-1)" RBM39 "CAPER, CAPERalpha, CC1.3, fSAP59, HCC1, RNPC2" ENSG00000131051 "RNA binding motif protein 39" Q14498 20 35701347-35742312 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Activator, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 162.0" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001591 Supported Supported "Nucleoplasm,Nuclear speckles,Microtubules,Centriolar satellite" NA NA 17000 "Cluster 35: Neutrophils - Protein binding" "Cluster 15: Bone marrow - Innate immune response" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 632 "Nucleoplasm, Nuclear speckles" "Microtubules, Centriolar satellite" "HPA001591: " "unprognostic (3.08e-1)" "unprognostic (1.26e-1)" "unprognostic (7.99e-2)" "unprognostic (3.63e-2)" "unprognostic (9.64e-2)" "unprognostic (1.32e-1)" "unprognostic (9.81e-2)" "unprognostic (1.55e-2)" "unprognostic (9.28e-2)" "potential prognostic unfavorable (4.19e-4)" "validated prognostic favorable (8.24e-8)" "validated prognostic favorable (1.91e-4)" "unprognostic (1.94e-1)" "unprognostic (2.10e-3)" "unprognostic (8.39e-2)" "unprognostic (1.92e-1)" "unprognostic (4.67e-3)" "unprognostic (1.35e-1)" "unprognostic (1.54e-2)" "unprognostic (1.26e-1)" "unprognostic (2.91e-1)" "unprognostic (8.41e-2)" "potential prognostic unfavorable (5.36e-4)" "unprognostic (6.32e-2)" "unprognostic (4.26e-1)" "unprognostic (5.69e-2)" "unprognostic (1.33e-2)" "unprognostic (7.98e-2)" "unprognostic (9.13e-2)" "unprognostic (1.32e-1)" "unprognostic (1.43e-1)" RBM4 "LARK, RBM4A, ZCCHC21, ZCRB3A" ENSG00000173933 "RNA binding motif protein 4" Q9BWF3 11 66638667-66668374 "Predicted intracellular proteins" "Differentiation, mRNA processing, mRNA splicing, RNA-mediated gene silencing" "Activator, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042174, HPA047849" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 49: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 24: Non-specific - Unknown function" "Cluster 22: Non-specific - Basic cellular functions" 24 Nucleoplasm Cytosol "HPA042174: , HPA047849: " "unprognostic (2.87e-2)" "unprognostic (2.37e-1)" "unprognostic (4.64e-1)" "unprognostic (1.11e-1)" "unprognostic (1.18e-1)" "unprognostic (8.38e-2)" "unprognostic (1.24e-1)" "unprognostic (2.14e-3)" "unprognostic (2.40e-3)" "unprognostic (4.39e-2)" "validated prognostic favorable (4.00e-6)" "validated prognostic favorable (5.25e-4)" "unprognostic (1.42e-1)" "validated prognostic unfavorable (3.13e-6)" "validated prognostic unfavorable (1.04e-4)" "unprognostic (5.46e-2)" "potential prognostic unfavorable (8.85e-4)" "unprognostic (2.73e-3)" "unprognostic (2.43e-2)" "unprognostic (2.38e-1)" "unprognostic (1.42e-2)" "unprognostic (2.74e-1)" "unprognostic (5.15e-3)" "unprognostic (7.59e-2)" "unprognostic (4.46e-2)" "unprognostic (6.83e-2)" "unprognostic (1.77e-2)" "unprognostic (2.50e-1)" "unprognostic (1.18e-1)" "unprognostic (1.30e-1)" "unprognostic (7.00e-2)" RBM41 FLJ11016 ENSG00000089682 "RNA binding motif protein 41" Q96IZ5 X 107061885-107118823 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Sertoli cells: 342.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042881 Approved Approved "Nuclear speckles,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 36: Non-specific - mRNA processing" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 27 "Nuclear speckles, Cytosol" "HPA042881: " "unprognostic (5.99e-2)" "unprognostic (3.97e-3)" "unprognostic (6.52e-2)" "unprognostic (1.32e-1)" "unprognostic (2.46e-2)" "unprognostic (1.20e-1)" "unprognostic (3.70e-1)" "unprognostic (1.29e-2)" "unprognostic (9.95e-2)" "potential prognostic unfavorable (1.66e-4)" "unprognostic (8.01e-3)" "unprognostic (8.36e-2)" "unprognostic (1.21e-2)" "unprognostic (4.23e-2)" "unprognostic (8.14e-2)" "unprognostic (1.49e-2)" "potential prognostic unfavorable (8.39e-4)" "unprognostic (7.39e-2)" "unprognostic (2.95e-1)" "unprognostic (1.13e-1)" "unprognostic (2.66e-2)" "validated prognostic unfavorable (4.11e-4)" "validated prognostic unfavorable (7.74e-4)" "unprognostic (1.74e-2)" "unprognostic (2.20e-3)" "unprognostic (1.08e-1)" "unprognostic (2.02e-1)" "unprognostic (1.99e-1)" "unprognostic (9.85e-2)" "unprognostic (2.56e-3)" "unprognostic (2.75e-1)" RBM42 MGC10433 ENSG00000126254 "RNA binding motif protein 42" Q9BTD8 19 35629030-35637686 "Essential proteins, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 234.4;Migrating cytotrophoblasts: 180.7;Oocytes: 193.4;Syncytiotrophoblasts: 517.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043671 Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 232 Nucleoplasm Cytosol "HPA043671: " "unprognostic (9.24e-2)" "unprognostic (1.87e-2)" "unprognostic (1.06e-1)" "unprognostic (2.06e-1)" "unprognostic (2.99e-1)" "unprognostic (2.67e-1)" "unprognostic (2.48e-1)" "unprognostic (2.55e-1)" "unprognostic (4.99e-2)" "unprognostic (1.51e-1)" "unprognostic (2.53e-1)" "unprognostic (3.68e-1)" "unprognostic (3.93e-2)" "validated prognostic unfavorable (3.18e-4)" "validated prognostic unfavorable (1.33e-4)" "unprognostic (1.56e-3)" "unprognostic (2.47e-2)" "unprognostic (1.43e-1)" "unprognostic (2.67e-1)" "unprognostic (2.83e-2)" "unprognostic (4.69e-2)" "unprognostic (6.90e-2)" "unprognostic (9.17e-2)" "unprognostic (1.05e-1)" "unprognostic (2.74e-1)" "unprognostic (2.91e-2)" "unprognostic (4.67e-2)" "unprognostic (1.13e-1)" "unprognostic (1.95e-3)" "unprognostic (1.65e-1)" "unprognostic (1.77e-1)" RBM43 "C2orf38, FLJ45645" ENSG00000184898 "RNA binding motif protein 43" Q6ZSC3 2 151247940-151261863 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fallopian tube ciliated cells: 65.8;Respiratory ciliated cells: 55.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" HPA038204 Uncertain Approved Nucleoplasm,Nucleoli NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 75: Ovary - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 94: Gonadal somatic cells - Mixed function" 2 Nucleoli Nucleoplasm "HPA038204: " "unprognostic (4.69e-3)" "unprognostic (1.71e-1)" "unprognostic (4.74e-1)" "unprognostic (9.82e-2)" "unprognostic (1.78e-1)" "unprognostic (1.69e-2)" "unprognostic (8.64e-2)" "unprognostic (5.25e-3)" "unprognostic (1.36e-1)" "unprognostic (1.15e-3)" "potential prognostic favorable (2.94e-7)" "unprognostic (3.81e-3)" "unprognostic (2.55e-1)" "unprognostic (2.38e-2)" "unprognostic (9.96e-3)" "unprognostic (1.26e-1)" "unprognostic (1.82e-1)" "unprognostic (3.78e-2)" "unprognostic (1.38e-1)" "unprognostic (1.69e-1)" "unprognostic (1.53e-2)" "unprognostic (1.82e-2)" "unprognostic (1.85e-1)" "unprognostic (1.40e-1)" "unprognostic (2.02e-1)" "unprognostic (7.94e-2)" "unprognostic (2.34e-1)" "unprognostic (1.23e-3)" "unprognostic (9.58e-2)" "unprognostic (1.82e-2)" "unprognostic (3.15e-1)" RBM44 FLJ40411 ENSG00000177483 "RNA binding motif protein 44" Q6ZP01 2 237798389-237842808 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 30 "testis: 14.7" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 68.3;Early primary spermatocytes: 123.1;Early spermatids: 26.3;Endometrial luminal cells: 37.5;Late primary spermatocytes: 29.2;Late spermatids: 25.2" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 13 "basophil: 1.3" "Lineage enriched" "Detected in single" 13 "granulocytes: 1.3" "Not detected" "Not detected" "Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA003298 Enhanced Approved Cytosol NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 3: Early primary spermatocytes - Early meiosis" Cytosol "HPA003298: " "unprognostic (1.68e-1)" "unprognostic (1.54e-1)" "unprognostic (1.15e-2)" RBM45 "DRB1, FLJ44612" ENSG00000155636 "RNA binding motif protein 45" Q8IUH3 2 178112424-178139011 "Plasma proteins, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Sertoli cells: 59.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020448 Approved Supported Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 7: Non-specific - Transcription" 29 Nucleoplasm "HPA020448: " "unprognostic (1.13e-2)" "unprognostic (7.47e-3)" "unprognostic (1.38e-2)" "unprognostic (7.26e-2)" "unprognostic (1.08e-1)" "unprognostic (4.11e-2)" "unprognostic (1.75e-1)" "unprognostic (9.49e-3)" "unprognostic (1.18e-1)" "unprognostic (1.10e-2)" "unprognostic (1.28e-3)" "unprognostic (2.04e-2)" "unprognostic (1.19e-1)" "potential prognostic unfavorable (9.88e-6)" "unprognostic (1.28e-3)" "unprognostic (5.42e-2)" "unprognostic (3.94e-2)" "unprognostic (2.08e-2)" "unprognostic (1.53e-1)" "unprognostic (4.41e-2)" "unprognostic (1.11e-3)" "unprognostic (3.83e-1)" "unprognostic (6.74e-2)" "unprognostic (3.63e-1)" "unprognostic (1.33e-2)" "unprognostic (1.88e-1)" "potential prognostic unfavorable (5.37e-6)" "unprognostic (8.34e-2)" "unprognostic (1.27e-1)" "unprognostic (2.99e-1)" "unprognostic (2.44e-1)" RBM46 "CT68, MGC27016" ENSG00000151962 "RNA binding motif protein 46" Q8TBY0 4 154781213-154828813 "Predicted intracellular proteins" "Differentiation, Meiosis, Oogenesis, Spermatogenesis" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 55 "testis: 25.8" "Group enriched" "Detected in some" 18 "Differentiating spermatogonia: 117.8;Early primary spermatocytes: 134.3;Late primary spermatocytes: 118.2;Oocytes: 133.5;Undifferentiated spermatogonia: 75.4" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 4.0" "Cancer enriched" "Detected in single" 15 "Testicular Germ Cell Tumor (TCGA): 4.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Myeloma: 5.6" "Colon - Enteric glia cells, Testis - Spermatocytes" "Low region specificity" "Detected in single" "Region enriched" "Detected in single" 20 "spinal cord: 16.9" "HPA037746, HPA038431" Approved "Nucleoli fibrillar center,Cytosol" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 8 Cytosol "Nucleoli fibrillar center" "HPA037746: , HPA038431: " "unprognostic (1.38e-1)" RBM47 "FLJ20273, NET18" ENSG00000163694 "RNA binding motif protein 47" A0AV96 4 40423267-40630875 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 2488.6;Esophageal apical cells: 2084.0;monocytes: 1608.9;Neutrophils: 4921.4;Syncytiotrophoblasts: 1575.8;Urothelial cells: 1824.4" "Group enriched" "Detected in all" 10 "central nervous system macrophage: 589.3;choroid plexus epithelial cell: 1934.4" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "choroid plexus: 91.9" "Immune cell enhanced" "Detected in many" "neutrophil: 136.7" "Group enriched" "Detected in many" 13 "dendritic cells: 34.4;granulocytes: 136.7;monocytes: 45.5" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Heart muscle - Macrophages, Prostate - Prostate glandular cells, Skeletal muscle - Macrophages, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA006347 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 24: Neutrophils - Innate immunity signal integration" 16 "Nucleoplasm, Cytosol" "HPA006347: " "potential prognostic favorable (9.21e-6)" "unprognostic (2.08e-2)" "unprognostic (1.62e-2)" "unprognostic (9.10e-2)" "unprognostic (8.64e-3)" "unprognostic (1.25e-1)" "unprognostic (2.44e-2)" "unprognostic (8.89e-3)" "unprognostic (1.80e-2)" "potential prognostic unfavorable (7.59e-4)" "validated prognostic favorable (3.57e-10)" "validated prognostic favorable (2.16e-4)" "unprognostic (2.23e-3)" "unprognostic (6.01e-3)" "unprognostic (3.82e-2)" "unprognostic (2.02e-1)" "unprognostic (4.38e-1)" "unprognostic (7.70e-2)" "unprognostic (6.14e-2)" "unprognostic (1.25e-1)" "unprognostic (3.03e-1)" "unprognostic (5.89e-2)" "unprognostic (5.65e-2)" "unprognostic (2.47e-1)" "unprognostic (2.11e-2)" "unprognostic (6.89e-2)" "unprognostic (5.90e-2)" "unprognostic (2.03e-2)" "unprognostic (1.40e-1)" "unprognostic (6.25e-2)" "unprognostic (2.03e-1)" RBM48 "C7orf64, DKFZp564O0523, HSPC304" ENSG00000127993 "RNA binding motif protein 48" Q5RL73 7 92528773-92540481 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021777, HPA025306" Uncertain Enhanced Nucleoplasm NA NA "Cluster 41: Basophils - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 34: Non-specific - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 27 Nucleoplasm "HPA021777: , HPA025306: " "unprognostic (6.39e-2)" "unprognostic (5.15e-2)" "unprognostic (7.24e-2)" "unprognostic (1.60e-2)" "unprognostic (1.77e-1)" "unprognostic (1.38e-2)" "unprognostic (9.66e-2)" "unprognostic (1.26e-1)" "potential prognostic unfavorable (3.16e-4)" "validated prognostic favorable (7.79e-4)" "validated prognostic favorable (9.14e-4)" "unprognostic (6.17e-3)" "potential prognostic unfavorable (2.07e-4)" "unprognostic (3.41e-1)" "unprognostic (1.56e-1)" "unprognostic (9.63e-2)" "unprognostic (1.15e-1)" "unprognostic (9.89e-2)" "unprognostic (4.12e-2)" "unprognostic (4.26e-2)" "unprognostic (1.29e-3)" "unprognostic (6.43e-2)" "unprognostic (4.65e-3)" "unprognostic (1.67e-1)" "unprognostic (2.66e-2)" "unprognostic (6.22e-2)" "unprognostic (3.83e-2)" "unprognostic (2.57e-2)" "unprognostic (1.86e-2)" RBM4B "MGC10871, RBM30, RBM4L, ZCCHC15, ZCCHC21B, ZCRB3B" ENSG00000173914 "RNA binding motif protein 4B" Q9BQ04 11 66664998-66677887 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Activator, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 166.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042174, HPA047849" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 65: Brain - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 24: Non-specific - Unknown function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 137 Nucleoplasm Cytosol "HPA042174: , HPA047849: " "unprognostic (5.37e-2)" "potential prognostic unfavorable (6.43e-4)" "unprognostic (1.31e-2)" "unprognostic (8.71e-2)" "unprognostic (2.86e-2)" "unprognostic (4.81e-2)" "unprognostic (2.70e-1)" "potential prognostic favorable (7.41e-4)" "unprognostic (1.62e-1)" "unprognostic (7.06e-3)" "unprognostic (5.93e-2)" "unprognostic (2.61e-2)" "unprognostic (1.27e-1)" "unprognostic (4.80e-3)" "unprognostic (1.58e-1)" "unprognostic (6.04e-2)" "unprognostic (7.28e-2)" "unprognostic (1.42e-1)" "unprognostic (4.33e-2)" "unprognostic (1.12e-1)" "unprognostic (3.97e-1)" "unprognostic (3.16e-3)" "unprognostic (1.16e-2)" "unprognostic (4.23e-3)" "unprognostic (2.06e-1)" "unprognostic (2.74e-1)" "unprognostic (4.20e-3)" "unprognostic (1.31e-1)" "unprognostic (4.14e-1)" "unprognostic (1.40e-1)" "unprognostic (1.12e-1)" RBM5 "H37, LUCA-15, LUCA15" ENSG00000003756 "RNA binding motif protein 5" P52756 3 50088919-50119021 "Predicted intracellular proteins" "Apoptosis, mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 325.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017335, HPA018011" Approved Supported "Nucleoplasm,Perinuclear theca,Flagellar centriole,Mid piece,Principal piece,End piece" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 64: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Transcription" 34 Nucleoplasm "Perinuclear theca, Flagellar centriole, Mid piece, Principal piece, End piece" "HPA017335: , HPA018011: " "unprognostic (1.03e-1)" "unprognostic (1.33e-1)" "unprognostic (6.04e-3)" "unprognostic (5.43e-2)" "unprognostic (4.88e-2)" "unprognostic (2.75e-1)" "unprognostic (1.75e-1)" "potential prognostic favorable (6.20e-4)" "unprognostic (2.40e-2)" "unprognostic (3.12e-2)" "unprognostic (7.80e-2)" "unprognostic (1.18e-2)" "potential prognostic favorable (8.82e-4)" "unprognostic (2.70e-3)" "unprognostic (3.39e-1)" "unprognostic (1.49e-2)" "unprognostic (1.06e-1)" "unprognostic (2.27e-1)" "unprognostic (4.23e-2)" "unprognostic (8.65e-2)" "unprognostic (1.36e-1)" "potential prognostic favorable (1.12e-4)" "unprognostic (7.48e-3)" "unprognostic (2.87e-2)" "unprognostic (7.34e-2)" "unprognostic (1.00e-1)" "unprognostic (1.14e-1)" "unprognostic (2.12e-1)" "unprognostic (1.54e-1)" "unprognostic (2.21e-1)" "unprognostic (1.89e-1)" RBM6 "3G2, DEF-3, DEF3, g16, NY-LU-12" ENSG00000004534 "RNA binding motif protein 6" P78332 3 49940007-50100045 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026272, HPA027164" Enhanced Approved "Nuclear speckles,Cytoplasmic bodies" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 64: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 37 "Nuclear speckles" "Cytoplasmic bodies" "HPA026272: , HPA027164: " "unprognostic (9.41e-3)" "unprognostic (5.30e-2)" "unprognostic (4.03e-2)" "unprognostic (4.61e-1)" "unprognostic (3.86e-2)" "unprognostic (4.28e-2)" "unprognostic (2.96e-1)" "unprognostic (6.23e-2)" "unprognostic (1.71e-2)" "unprognostic (1.77e-2)" "potential prognostic unfavorable (6.38e-5)" "unprognostic (8.77e-2)" "unprognostic (5.43e-2)" "unprognostic (1.06e-3)" "unprognostic (2.30e-1)" "unprognostic (2.01e-2)" "unprognostic (2.51e-1)" "unprognostic (1.51e-1)" "unprognostic (6.33e-2)" "unprognostic (2.61e-1)" "unprognostic (1.96e-1)" "potential prognostic favorable (3.84e-4)" "unprognostic (2.15e-2)" "unprognostic (7.56e-2)" "unprognostic (5.65e-2)" "unprognostic (1.19e-2)" "unprognostic (2.37e-3)" "unprognostic (1.70e-1)" "unprognostic (1.14e-1)" "unprognostic (2.10e-1)" "unprognostic (8.31e-2)" RBM7 ENSG00000076053 "RNA binding motif protein 7" Q9Y580 11 114400030-114414203 "Predicted intracellular proteins" Meiosis RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 37.5" "Cell type enhanced" "Detected in many" "Adipocytes: 19.6;Cardiomyocytes: 63.6;Early spermatids: 14.1;Endometrial secretory cells: 7.1;Epicardial cells: 13.6;Late primary spermatocytes: 9.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013993, HPA048003" Supported Enhanced Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 85 Nucleoplasm "HPA013993: , HPA048003: " "unprognostic (6.01e-3)" "unprognostic (4.60e-3)" "unprognostic (1.66e-2)" "potential prognostic unfavorable (7.74e-6)" "unprognostic (1.03e-1)" "unprognostic (2.81e-1)" "unprognostic (1.62e-1)" "unprognostic (5.30e-2)" "unprognostic (6.75e-2)" "unprognostic (1.48e-3)" "potential prognostic favorable (1.31e-5)" "unprognostic (2.96e-3)" "unprognostic (2.02e-1)" "unprognostic (1.48e-1)" "unprognostic (3.94e-1)" "unprognostic (2.63e-1)" "unprognostic (2.02e-2)" "unprognostic (7.10e-2)" "unprognostic (1.68e-1)" "unprognostic (2.01e-1)" "potential prognostic unfavorable (2.81e-4)" "unprognostic (1.52e-2)" "unprognostic (1.08e-3)" "unprognostic (2.37e-1)" "unprognostic (3.63e-2)" "unprognostic (8.69e-2)" "unprognostic (6.97e-2)" "unprognostic (1.53e-1)" "unprognostic (1.19e-1)" "unprognostic (2.13e-1)" "unprognostic (7.63e-3)" RBM8A "BOV-1A, BOV-1B, BOV-1C, RBM8, RBM8B, Y14, ZNRP" ENSG00000265241 "RNA binding motif protein 8A" Q9Y5S9 1 145921556-145927678 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "mRNA processing, mRNA splicing, mRNA transport, Nonsense-mediated mRNA decay, Translation regulation, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 193.4;Epididymal basal cells: 231.0;Esophageal apical cells: 376.1;Extravillous trophoblasts: 222.3;Gastric progenitor cells: 225.6;Migrating cytotrophoblasts: 205.4;Syncytiotrophoblasts: 335.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018403 Supported Supported "Nuclear speckles" NA NA 120000 "Cluster 29: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Ribosome" "Cluster 45: Non-specific - Nuclear processes" "Cluster 15: Non-specific - Protein processing" 315 "Nuclear speckles" "HPA018403: " "unprognostic (6.84e-3)" "unprognostic (1.49e-1)" "unprognostic (2.91e-2)" "unprognostic (5.68e-3)" "unprognostic (5.49e-2)" "unprognostic (1.46e-1)" "unprognostic (1.37e-1)" "unprognostic (7.73e-3)" "unprognostic (2.65e-2)" "unprognostic (3.20e-3)" "unprognostic (6.10e-2)" "unprognostic (5.29e-2)" "potential prognostic unfavorable (5.80e-6)" "unprognostic (5.02e-3)" "unprognostic (2.91e-3)" "unprognostic (4.47e-3)" "unprognostic (6.00e-2)" "unprognostic (1.55e-1)" "unprognostic (2.28e-1)" "unprognostic (1.90e-3)" "unprognostic (4.48e-2)" "unprognostic (3.14e-1)" "unprognostic (3.68e-2)" "unprognostic (2.08e-1)" "unprognostic (3.02e-1)" "unprognostic (2.29e-1)" "unprognostic (1.45e-1)" "unprognostic (9.40e-2)" RBMS1 "C2orf12, DKFZp564H0764, HCC-4, MSSP-1, MSSP-2, MSSP-3, SCR2, YC1" ENSG00000153250 "RNA binding motif single stranded interacting protein 1" P29558 2 160272151-160493807 "Predicted intracellular proteins" "DNA replication" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 972.4;Podocytes: 1015.9;Syncytiotrophoblasts: 899.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Liver - Vascular endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047943, HPA061791" Enhanced Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 9: T-cells - Adaptive immunity: Regulation" 9 Cytosol "HPA047943: , HPA061791: " "unprognostic (1.56e-2)" "unprognostic (2.51e-1)" "unprognostic (2.49e-3)" "unprognostic (7.83e-3)" "unprognostic (8.39e-3)" "unprognostic (9.11e-2)" "unprognostic (1.25e-1)" "unprognostic (6.00e-3)" "unprognostic (5.56e-2)" "unprognostic (2.48e-1)" "unprognostic (5.41e-2)" "unprognostic (1.87e-2)" "potential prognostic unfavorable (3.31e-5)" "unprognostic (1.75e-3)" "unprognostic (8.71e-2)" "unprognostic (1.56e-2)" "unprognostic (3.33e-2)" "unprognostic (2.22e-1)" "potential prognostic unfavorable (8.39e-4)" "unprognostic (1.99e-2)" "unprognostic (1.43e-3)" "unprognostic (3.16e-2)" "potential prognostic unfavorable (6.95e-4)" "unprognostic (6.41e-2)" "unprognostic (1.44e-1)" "unprognostic (3.99e-2)" "unprognostic (1.19e-1)" "potential prognostic unfavorable (1.80e-4)" "unprognostic (1.40e-1)" "unprognostic (1.78e-1)" "unprognostic (1.60e-1)" RBMS2 SCR3 ENSG00000076067 "RNA binding motif single stranded interacting protein 2" Q15434 12 56521820-56596193 "Plasma proteins, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 231.4;Vascular endothelial cells: 234.8" "Cell type enhanced" "Detected in all" "endothelial cell: 368.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 4.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Pituitary gland - Endothelial cells, Skeletal muscle - Endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039225, HPA058784" Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 98 "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "HPA039225: , HPA058784: " "unprognostic (1.49e-1)" "unprognostic (1.34e-1)" "unprognostic (1.27e-2)" "unprognostic (1.47e-3)" "unprognostic (9.52e-2)" "unprognostic (4.25e-2)" "unprognostic (3.23e-2)" "unprognostic (2.15e-1)" "unprognostic (3.70e-2)" "unprognostic (8.41e-3)" "validated prognostic favorable (5.32e-7)" "validated prognostic favorable (1.15e-5)" "unprognostic (1.98e-2)" "unprognostic (4.38e-2)" "unprognostic (3.63e-2)" "unprognostic (5.37e-2)" "unprognostic (5.57e-3)" "unprognostic (3.38e-2)" "unprognostic (3.87e-2)" "unprognostic (9.30e-2)" "unprognostic (3.58e-3)" "potential prognostic unfavorable (9.86e-4)" "unprognostic (1.82e-2)" "unprognostic (4.14e-1)" "unprognostic (6.59e-2)" "unprognostic (1.38e-2)" "unprognostic (7.39e-2)" "unprognostic (6.67e-2)" "unprognostic (1.81e-1)" "unprognostic (2.99e-1)" "unprognostic (6.82e-2)" RBMS3 ENSG00000144642 "RNA binding motif single stranded interacting protein 3" Q6XE24 3 28574791-30010391 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 562.6;Astrocytes: 1452.6;Bergmann glia: 645.6;Brain inhibitory neurons: 804.1;Choroid plexus epithelial cells: 469.7;Fibro-adipogenic progenitors: 575.5;Fibroblasts: 649.2;Leydig cells: 650.4;Medullary thymic epithelial cells: 516.0;Oligodendrocyte progenitor cells: 980.7;Other brain neurons: 605.3;Pericytes: 536.4" "Cell type enhanced" "Detected in all" "fibroblast: 5086.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "plasmacytoid DC: 4.1" "Lineage enriched" "Detected in single" 8 "dendritic cells: 4.1" "Cancer enhanced" "Detected in many" "Neuroblastoma: 27.7" "Adrenal gland - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblasts_1, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034719 Uncertain Approved Vesicles NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 22: Non-specific - Basic cellular functions" Vesicles "HPA034719: " "unprognostic (3.04e-3)" "unprognostic (7.79e-2)" "unprognostic (3.44e-1)" "unprognostic (1.47e-2)" "unprognostic (9.24e-2)" "unprognostic (7.67e-2)" "unprognostic (3.56e-2)" "unprognostic (3.84e-1)" "validated prognostic favorable (4.14e-4)" "validated prognostic favorable (9.17e-4)" "unprognostic (4.95e-2)" "potential prognostic favorable (7.91e-4)" "unprognostic (1.26e-2)" "unprognostic (1.36e-2)" "unprognostic (1.89e-1)" "unprognostic (3.29e-1)" "unprognostic (1.51e-2)" "unprognostic (8.04e-2)" "unprognostic (2.94e-1)" "unprognostic (1.35e-1)" "unprognostic (4.73e-2)" "unprognostic (1.04e-1)" "unprognostic (6.28e-2)" "unprognostic (2.34e-3)" "unprognostic (6.70e-2)" "unprognostic (4.15e-2)" "unprognostic (1.06e-3)" RBMX "hnRNP-G, HNRNPG, RNMX" ENSG00000147274 "RNA binding motif protein X-linked" P38159 X 136848004-136880764 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, Transcription" "Activator, Repressor, Ribonucleoprotein, RNA-binding" "Cancer-related genes, Deafness, Epilepsy, Intellectual disability, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057707 Supported Supported Nucleoplasm NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 54: Non-specific - Ribosome" "Cluster 55: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 15: Non-specific - Protein processing" 173 Nucleoplasm "HPA057707: " "unprognostic (1.26e-2)" "unprognostic (6.59e-2)" "unprognostic (2.57e-1)" "unprognostic (3.70e-2)" "unprognostic (3.01e-3)" "unprognostic (5.72e-2)" "unprognostic (4.04e-2)" "unprognostic (5.24e-3)" "unprognostic (7.86e-2)" "unprognostic (2.47e-2)" "validated prognostic favorable (2.56e-9)" "validated prognostic favorable (1.28e-4)" "unprognostic (6.03e-3)" "potential prognostic unfavorable (9.37e-4)" "unprognostic (2.50e-3)" "unprognostic (1.00e-2)" "unprognostic (3.98e-3)" "unprognostic (2.10e-1)" "unprognostic (2.55e-1)" "unprognostic (4.76e-2)" "unprognostic (1.76e-1)" "unprognostic (2.35e-2)" "unprognostic (7.85e-2)" "unprognostic (5.13e-2)" "unprognostic (2.63e-2)" "unprognostic (6.47e-2)" "unprognostic (1.25e-1)" "unprognostic (1.68e-1)" "unprognostic (3.15e-1)" "unprognostic (1.28e-1)" "unprognostic (1.09e-1)" RBMX2 "CGI-79, Snu17" ENSG00000134597 "RNA binding motif protein X-linked 2" Q9Y388 X 130401987-130413656 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Oocytes: 405.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026609 Approved Supported "Nuclear membrane,Nucleoli,Endoplasmic reticulum" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 54: Non-specific - Ribosome" "Cluster 34: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 41: Oocytes - Oogenesis" 41 "Nuclear membrane" "Nucleoli, Endoplasmic reticulum" "HPA026609: " "unprognostic (8.69e-2)" "unprognostic (1.32e-1)" "unprognostic (4.75e-2)" "unprognostic (7.08e-2)" "unprognostic (1.51e-2)" "unprognostic (7.62e-2)" "unprognostic (3.05e-1)" "unprognostic (7.23e-3)" "unprognostic (1.40e-2)" "potential prognostic unfavorable (7.78e-4)" "unprognostic (1.61e-1)" "unprognostic (1.23e-1)" "unprognostic (6.66e-3)" "validated prognostic unfavorable (7.08e-5)" "validated prognostic unfavorable (6.88e-4)" "unprognostic (9.37e-2)" "potential prognostic unfavorable (6.64e-4)" "unprognostic (6.08e-2)" "unprognostic (1.60e-1)" "unprognostic (3.95e-2)" "unprognostic (1.11e-1)" "unprognostic (2.15e-1)" "unprognostic (2.18e-2)" "unprognostic (2.28e-1)" "unprognostic (2.14e-1)" "unprognostic (3.92e-1)" "unprognostic (1.62e-3)" "unprognostic (2.48e-1)" "unprognostic (3.56e-1)" "unprognostic (6.69e-2)" "unprognostic (3.60e-1)" RBMXL1 KAT3 ENSG00000213516 "RBMX like 1" Q96E39 1 88979456-88992960 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal basal cells: 5.7;Fallopian secretory cells: 4.9;Lacrimal acinar cells: 4.5;Medullary thymic epithelial cells: 4.8;Retinal horizontal cells: 4.0" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA057707 Supported Approved Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 11 Nucleoplasm "HPA057707: " "unprognostic (1.22e-1)" "unprognostic (5.80e-2)" "unprognostic (6.08e-2)" "unprognostic (6.59e-3)" "unprognostic (2.13e-1)" "unprognostic (1.65e-1)" "unprognostic (1.36e-1)" "unprognostic (2.46e-1)" "unprognostic (9.24e-2)" "potential prognostic unfavorable (2.41e-5)" "validated prognostic favorable (1.67e-6)" "validated prognostic favorable (7.68e-4)" "unprognostic (3.41e-1)" "unprognostic (2.04e-3)" "unprognostic (1.83e-2)" "unprognostic (7.89e-2)" "unprognostic (3.08e-2)" "unprognostic (1.60e-1)" "unprognostic (3.98e-3)" "unprognostic (3.72e-2)" "unprognostic (3.45e-2)" "potential prognostic unfavorable (1.19e-4)" "unprognostic (1.25e-1)" "unprognostic (3.35e-1)" "unprognostic (4.25e-3)" "unprognostic (1.93e-1)" "unprognostic (1.66e-1)" "unprognostic (1.21e-1)" "unprognostic (1.77e-1)" "unprognostic (9.37e-2)" "unprognostic (1.09e-1)" RBMXL2 "HNRNPG-T, HNRPGT" ENSG00000170748 "RBMX like 2" O75526 11 7088998-7091148 "Predicted intracellular proteins" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 203 "testis: 29.3" "Group enriched" "Detected in some" 13 "Early primary spermatocytes: 110.9;Early spermatids: 134.7;Late primary spermatocytes: 316.8;Late spermatids: 247.2" "Cell type enriched" "Detected in single" 5 "ependymal cell: 1.4" "Cancer enriched" "Detected in single" 86 "Testicular Germ Cell Tumor (TCGA): 8.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "HPA038912, HPA051842" Enhanced NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 2 "HPA038912: , HPA051842: " "unprognostic (1.88e-1)" RBMXL3 "CXorf55, FLJ40249" ENSG00000175718 "RBMX like 3" Q8N7X1 X 115189410-115192868 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 26 "testis: 2.6" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 15.8;Early primary spermatocytes: 26.1;Epicardial cells: 2.3;Undifferentiated spermatogonia: 5.3" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 20 "Testicular Germ Cell Tumor (TCGA): 2.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Spermatocytes, Testis - Spermatogonia" HPA051842 Supported NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 24: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 3: Early primary spermatocytes - Early meiosis" "HPA051842: " "unprognostic (2.86e-1)" RBMY1A1 "RBM1, RBM2, YRRM1, YRRM2" ENSG00000234414 "RNA binding motif protein Y-linked family 1 member A1" P0DJD3 Y 21534879-21549326 "Human disease related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Activator, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 80 "testis: 8.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 3.1;liver cancer: 2.3" "HPA001534, HPA053147, HPA057723" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 20: Myeloma - Immune response" 16 Nucleoplasm Nucleoli "HPA001534: , HPA053147: , HPA057723: " RBMY1B ENSG00000242875 "RNA binding motif protein Y-linked family 1 member B" A6NDE4 Y 21511338-21525786 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Neuroblastoma: 1.2" "HPA001534, HPA053147, HPA057723" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 17: Neuroblastoma - Neuronal signaling" 1 Nucleoplasm Nucleoli "HPA001534: , HPA053147: , HPA057723: " RBMY1D ENSG00000244395 "RNA binding motif protein Y-linked family 1 member D" P0C7P1 Y 21880076-21894526 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 13 "testis: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001534, HPA053147, HPA057723" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 7: Liver cancer - Metabolism" Nucleoplasm Nucleoli "HPA001534: , HPA053147: , HPA057723: " RBMY1E ENSG00000242389 "RNA binding motif protein Y-linked family 1 member E" A6NEQ0 Y 21903618-21918042 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 26 "testis: 2.6" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 1.4;Early primary spermatocytes: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001534, HPA053147, HPA057723" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 20: Myeloma - Immune response" "Cluster 3: Early primary spermatocytes - Early meiosis" 3 Nucleoplasm Nucleoli "HPA001534: , HPA053147: , HPA057723: " RBMY1F MGC33094 ENSG00000169800 "RNA binding motif protein Y-linked family 1 member F" Q15415 Y 22168542-22182982 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 31 "testis: 3.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 22 "Myeloma: 3.6" "HPA001534, HPA053147, HPA057723" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 20: Myeloma - Immune response" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 29 "Nucleoplasm, Nucleoli" "HPA001534: , HPA053147: , HPA057723: " RBMY1J ENSG00000226941 "RNA binding motif protein Y-linked family 1 member J" Q15415 Y 22403410-22417881 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 15 "testis: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 12 "Myeloma: 1.1" "HPA001534, HPA053147, HPA057723" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 20: Myeloma - Immune response" 29 Nucleoplasm Nucleoli "HPA001534: , HPA053147: , HPA057723: " RBP1 "CRABP-I, CRBP, CRBP1, CRBPI, RBPC" ENSG00000114115 "Retinol binding protein 1" P09455 3 139517434-139539829 "Metabolic proteins, Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 1159.9;ovary: 1363.3" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 2029.1;Endometrial stromal cells: 636.7;Fallopian tube ciliated cells: 1371.4;Granulosa cells: 1609.8;Hepatic stellate cells: 768.1;Ovarian stromal cells: 2163.7;Pancreatic acinar cells: 535.1;Retinal pigment epithelial cells: 3103.4" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 214.2;ependymal cell: 87.9" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "choroid plexus: 439.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 295.0" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Stomach - Fibroblasts, Testis - Leydig cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "basal ganglia: 89.1" "HPA007338, CAB018603, CAB019276" Enhanced Approved Nucleoplasm,Cytosol NA NA 19000 "Cluster 75: Ovary - Mixed function" "Cluster 36: Choroid plexus - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 94: Gonadal somatic cells - Mixed function" 7 Cytosol Nucleoplasm "CAB018603: , CAB019276: , HPA007338: " "unprognostic (4.52e-1)" "unprognostic (9.93e-3)" "unprognostic (3.79e-1)" "unprognostic (1.94e-1)" "unprognostic (8.12e-2)" "unprognostic (6.83e-2)" "unprognostic (5.00e-3)" "potential prognostic unfavorable (5.56e-6)" "unprognostic (5.26e-3)" "unprognostic (1.17e-1)" "unprognostic (2.31e-2)" "unprognostic (5.17e-2)" "unprognostic (3.18e-1)" "unprognostic (1.10e-1)" "unprognostic (5.30e-3)" "unprognostic (2.69e-1)" "unprognostic (1.68e-2)" "unprognostic (1.58e-1)" "unprognostic (1.61e-2)" "unprognostic (1.77e-2)" "unprognostic (9.98e-2)" "unprognostic (1.47e-2)" "potential prognostic unfavorable (3.84e-4)" "unprognostic (1.23e-1)" "unprognostic (1.71e-2)" "unprognostic (8.86e-2)" "unprognostic (3.32e-2)" "unprognostic (1.53e-2)" "unprognostic (1.19e-1)" "unprognostic (1.94e-2)" "unprognostic (2.20e-1)" RBP2 "CRABP-II, CRBP2, CRBPII, RBPC2" ENSG00000114113 "Retinol binding protein 2" P50120 3 139452884-139480747 "Metabolic proteins, Predicted intracellular proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 355 "intestine: 2547.7" "Cell type enriched" "Detected in many" 33 "Enterocytes: 5630.5" "Cell type enhanced" "Detected in many" "ependymal cell: 15.5" "Group enriched" "Detected in many" 4 "Colon Adenocarcinoma (TCGA): 12.6;Pancreatic Adenocarcinoma (TCGA): 11.1;Rectum Adenocarcinoma (TCGA): 11.1;Stomach Adenocarcinoma (TCGA): 16.9;Testicular Germ Cell Tumor (TCGA): 7.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "colorectal cancer: 8.3;liver cancer: 12.5;ovarian cancer: 21.0;Uterine cancer: 5.4" "Adrenal gland - Adrenal medulla cells, Lung - Alveolar cells type 1, Skin - Inner root sheath cells" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA035866 Enhanced Approved "Golgi apparatus" NA NA 700000 "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 46: Brainstem - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 1: Enterocytes - Absorption and Digestion" "Golgi apparatus" "HPA035866: " "unprognostic (5.31e-2)" "unprognostic (4.70e-3)" "unprognostic (1.50e-1)" "unprognostic (1.24e-1)" "unprognostic (1.01e-1)" "unprognostic (4.47e-2)" "unprognostic (2.52e-2)" "unprognostic (1.23e-1)" "unprognostic (1.26e-1)" "unprognostic (3.85e-3)" "unprognostic (1.04e-1)" "unprognostic (7.33e-2)" "unprognostic (2.13e-1)" "unprognostic (1.43e-2)" "unprognostic (4.43e-2)" "unprognostic (5.92e-2)" "unprognostic (6.80e-2)" "unprognostic (2.70e-2)" "unprognostic (4.65e-2)" RBP3 "D10S64, D10S65, D10S66, RP66" ENSG00000265203 "Retinol binding protein 3" P10745 10 47348363-47357881 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted secreted proteins" Transport "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 177 "retina: 504.0" "Group enriched" "Detected in some" 7 "Cone photoreceptor cells: 550.7;Rod photoreceptor cells: 576.8" "Group enriched" "Detected in some" 5 "committed oligodendrocyte precursor: 1.8;upper rhombic lip: 1.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "hippocampal formation: 1.3" "Low region specificity" "Detected in many" "HPA041301, HPA044239" Enhanced "Secreted in other tissues" Transport NA NA "Cluster 42: Retina - Visual perception" "Cluster 49: Hindbrain - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 79: Photoreceptor cells - Phototransduction" 9 "HPA041301: , HPA044239: " RBP4 ENSG00000138207 "Retinol binding protein 4" P02753 10 93591687-93601744 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Sensory transduction, Transport, Vision" "Cancer-related genes, Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 17 "liver: 11054.0" "Cell type enriched" "Detected in many" 13 "Hepatocytes: 15825.7" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in many" 10 "Liver Hepatocellular Carcinoma (TCGA): 6778.1" "Region enriched" "Detected in all" 4 "hypothalamus: 204.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "liver cancer: 195.7" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Lung - Macrophages, Minor Salivary Gland - Adipocytes (Minor salivary gland), Pancreas - Beta cells, Prostate - Fibroblasts, Skin - Adipocytes (Skin), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001641, CAB004555" Supported "Secreted to blood" Transport NA NA 46100000000 33000000000 "Cluster 53: Liver - Plasma proteins" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 18: Liver cancer - Metabolism" "Cluster 93: Hepatocytes - Bile production & excretion" 9 "CAB004555: , HPA001641: " "unprognostic (5.20e-2)" "unprognostic (1.08e-2)" "unprognostic (2.97e-2)" "unprognostic (2.68e-2)" "unprognostic (2.70e-2)" "unprognostic (1.50e-1)" "unprognostic (1.94e-2)" "unprognostic (1.92e-1)" "potential prognostic unfavorable (2.76e-4)" "unprognostic (1.43e-1)" "unprognostic (6.49e-2)" "potential prognostic favorable (3.70e-6)" "validated prognostic favorable (1.16e-7)" "validated prognostic favorable (9.68e-5)" "unprognostic (8.40e-2)" "unprognostic (2.38e-1)" "unprognostic (1.74e-1)" "unprognostic (3.01e-1)" "unprognostic (1.58e-2)" "unprognostic (5.50e-2)" "unprognostic (3.57e-1)" "unprognostic (1.20e-1)" "unprognostic (4.99e-1)" "unprognostic (3.43e-2)" "unprognostic (1.11e-1)" "unprognostic (2.18e-1)" "unprognostic (1.25e-3)" "unprognostic (1.58e-1)" "unprognostic (5.43e-2)" "unprognostic (1.77e-2)" RBP5 CRBPIII ENSG00000139194 "Retinol binding protein 5" P82980 12 7115736-7128889 "Plasma proteins, Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "kidney: 453.2;liver: 329.2" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 216.7" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 9 "Kidney Renal Clear Cell Carcinoma (TCGA): 190.6;Kidney Renal Papillary Cell Carcinoma (TCGA): 113.0;Liver Hepatocellular Carcinoma (TCGA): 79.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Thyroid gland - T-cells" "Low region specificity" "Detected in all" HPA038723 Enhanced Approved "Golgi apparatus,Vesicles" NA NA 5500 "Cluster 76: Non-specific - Metabolism" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 18: Liver cancer - Metabolism" "Cluster 93: Hepatocytes - Bile production & excretion" 2 "Golgi apparatus" Vesicles "HPA038723: " "unprognostic (1.47e-1)" "unprognostic (1.27e-2)" "unprognostic (1.77e-1)" "unprognostic (4.27e-3)" "unprognostic (8.97e-2)" "unprognostic (2.85e-1)" "unprognostic (3.26e-1)" "unprognostic (1.34e-3)" "unprognostic (2.10e-1)" "unprognostic (1.53e-3)" "unprognostic (1.14e-3)" "unprognostic (1.15e-2)" "unprognostic (7.73e-3)" "potential prognostic favorable (6.26e-4)" "potential prognostic favorable (8.03e-4)" "unprognostic (3.30e-1)" "unprognostic (3.82e-1)" "unprognostic (2.24e-1)" "unprognostic (7.47e-2)" "unprognostic (2.49e-1)" "unprognostic (5.97e-3)" "unprognostic (4.35e-3)" "unprognostic (2.39e-1)" "unprognostic (2.50e-1)" "unprognostic (7.95e-3)" "unprognostic (1.74e-2)" "unprognostic (6.27e-3)" "unprognostic (3.35e-1)" "unprognostic (2.62e-2)" RBP7 CRBPIV ENSG00000162444 "Retinol binding protein 7" Q96R05 1 9997206-10016021 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 390.0;breast: 412.3" "Group enriched" "Detected in many" 4 "Esophageal apical cells: 586.6;Kupffer cells: 987.0;Vascular endothelial cells: 377.0" "Cell type enhanced" "Detected in many" "oligodendrocyte: 37.6" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 92.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 312.6;neutrophil: 347.3" "Group enriched" "Detected in many" 31 "granulocytes: 347.3;monocytes: 312.6" "Cancer enriched" "Detected in many" 5 "Adrenocortical cancer: 99.4" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA034749 Enhanced Uncertain "Nuclear speckles,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 11: White matter - Signal transduction" "Cluster 1: Neuronal - Visual perception" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 8 "Nuclear speckles, Cytosol" "HPA034749: " "unprognostic (9.47e-2)" "unprognostic (1.07e-2)" "unprognostic (4.59e-2)" "unprognostic (1.61e-2)" "unprognostic (4.70e-2)" "unprognostic (9.73e-2)" "unprognostic (3.83e-1)" "unprognostic (4.90e-2)" "unprognostic (7.50e-2)" "unprognostic (7.20e-2)" "validated prognostic favorable (1.48e-9)" "validated prognostic favorable (3.71e-4)" "unprognostic (1.43e-1)" "unprognostic (4.90e-2)" "unprognostic (1.65e-2)" "unprognostic (6.39e-3)" "unprognostic (6.13e-2)" "unprognostic (7.84e-2)" "unprognostic (6.11e-2)" "unprognostic (2.72e-1)" "unprognostic (2.67e-2)" "unprognostic (4.45e-2)" "unprognostic (1.36e-1)" "unprognostic (1.44e-1)" "unprognostic (7.11e-2)" "unprognostic (5.07e-2)" "potential prognostic unfavorable (2.42e-4)" "unprognostic (2.85e-3)" "unprognostic (3.07e-1)" "unprognostic (2.01e-2)" "unprognostic (2.38e-3)" RBPJ "CBF1, IGKJRB, IGKJRB1, KBF2, RBP-J, RBPJK, RBPSUH, SUH" ENSG00000168214 "Recombination signal binding protein for immunoglobulin kappa J region" Q06330 4 26163455-26435131 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Notch signaling pathway, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "cDC: 731.7;Hofbauer cells: 4704.0;Macrophages: 1462.7;Neutrophils: 1204.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000251, HPA060647" Uncertain Supported Nucleoplasm NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 11: White matter - Signal transduction" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 77 Nucleoplasm "HPA000251: , HPA060647: " "unprognostic (3.09e-2)" "unprognostic (1.03e-1)" "unprognostic (7.91e-2)" "unprognostic (1.16e-1)" "unprognostic (2.18e-1)" "unprognostic (5.06e-2)" "unprognostic (4.39e-1)" "unprognostic (1.41e-2)" "unprognostic (9.82e-2)" "potential prognostic unfavorable (3.85e-6)" "potential prognostic favorable (7.73e-4)" "unprognostic (4.06e-3)" "unprognostic (2.95e-2)" "unprognostic (4.51e-3)" "unprognostic (1.85e-1)" "unprognostic (5.54e-2)" "potential prognostic unfavorable (2.10e-4)" "unprognostic (5.65e-2)" "unprognostic (1.97e-1)" "unprognostic (1.19e-1)" "unprognostic (1.45e-2)" "unprognostic (1.43e-1)" "unprognostic (9.85e-3)" "unprognostic (5.11e-2)" "unprognostic (7.93e-2)" "unprognostic (1.23e-1)" "unprognostic (9.33e-2)" "unprognostic (1.80e-1)" "unprognostic (2.38e-1)" "unprognostic (5.12e-3)" "unprognostic (1.87e-3)" RBPJL "RBP-L, RBPSUHL, SUH, SUHL" ENSG00000124232 "Recombination signal binding protein for immunoglobulin kappa J region like" Q9UBG7 20 45306840-45317824 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 244 "pancreas: 919.9" "Cell type enriched" "Detected in some" 21 "Pancreatic acinar cells: 975.0" "Cell type enhanced" "Detected in single" "miscellaneous: 1.1" "Cancer enhanced" "Detected in some" "Pancreatic Adenocarcinoma (TCGA): 5.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Stomach - Gastric enteroendocrine cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB006846 Enhanced NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 59: Leukemia - T-cell receptor" "Cluster 5: Pancreatic acinar cells - Pancreatic exocrine secretion" "CAB006846: " "unprognostic (5.17e-1)" "unprognostic (4.87e-2)" "unprognostic (1.56e-1)" "potential prognostic unfavorable (6.91e-4)" RBPMS HERMES ENSG00000157110 "RNA binding protein, mRNA processing factor" Q93062 8 30384511-30572256 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 551.9" "Cell type enhanced" "Detected in many" "Podocytes: 2053.4;Proximal tubule cells: 1140.6;Renal collecting duct intercalated cells: 1261.5;Renal collecting duct principal cells: 1713.8;Renal connecting tubule cells: 1596.9;Salivary myoepithelial cells: 1005.0;Smooth muscle cells: 1117.0;Vascular smooth muscle cells: 1336.8" "Cell type enhanced" "Detected in all" "pericyte: 874.4;vascular associated smooth muscle cell: 2005.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "plasmacytoid DC: 1.0" "Lineage enriched" "Detected in single" 5 "dendritic cells: 1.0" "Cancer enhanced" "Detected in many" "testis cancer: 187.1" "Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Endothelial cells, Pituitary gland - Endothelial cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056999 Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 110: Mural cells - ECM organization" 170 Nucleoplasm Cytosol "HPA056999: " "unprognostic (6.17e-3)" "unprognostic (1.17e-1)" "unprognostic (6.06e-2)" "unprognostic (2.38e-1)" "unprognostic (7.99e-2)" "unprognostic (2.35e-2)" "unprognostic (1.54e-2)" "unprognostic (2.37e-2)" "unprognostic (2.06e-1)" "unprognostic (1.51e-1)" "potential prognostic favorable (6.28e-4)" "unprognostic (1.05e-2)" "unprognostic (2.01e-3)" "unprognostic (2.44e-2)" "unprognostic (3.49e-1)" "unprognostic (7.57e-3)" "unprognostic (7.63e-2)" "unprognostic (2.84e-2)" "unprognostic (6.58e-2)" "unprognostic (8.46e-2)" "unprognostic (3.27e-1)" "unprognostic (3.77e-2)" "unprognostic (1.10e-1)" "unprognostic (5.51e-2)" "unprognostic (3.07e-1)" "unprognostic (4.80e-3)" "unprognostic (1.29e-1)" "unprognostic (1.08e-2)" "unprognostic (2.84e-1)" "unprognostic (5.57e-2)" "unprognostic (1.55e-1)" RBPMS2 ENSG00000166831 "RNA binding protein, mRNA processing factor 2" Q6ZRY4 15 64739891-64775589 "Predicted intracellular proteins" "Developmental protein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 138.0;heart muscle: 283.6;intestine: 138.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 46.5;Megakaryocyte progenitors: 94.9;Megakaryocytes: 420.4;Oocytes: 59.9;Parietal cells: 68.9;Platelets: 125.6;Smooth muscle cells: 125.9;Vascular smooth muscle cells: 135.6" "Group enriched" "Detected in some" 7 "choroid plexus epithelial cell: 20.3;pericyte: 54.4;vascular associated smooth muscle cell: 72.7" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 66.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 79.7" "Minor Salivary Gland - Endothelial cells, Prostate - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 62: Smooth muscle cells - Muscle contraction" 44 "unprognostic (2.06e-2)" "unprognostic (7.07e-2)" "unprognostic (1.90e-2)" "unprognostic (1.13e-1)" "unprognostic (1.48e-2)" "unprognostic (1.44e-1)" "unprognostic (1.02e-1)" "unprognostic (5.00e-3)" "unprognostic (9.04e-2)" "unprognostic (9.04e-3)" "validated prognostic favorable (6.88e-6)" "validated prognostic favorable (8.96e-7)" "potential prognostic favorable (8.91e-5)" "unprognostic (7.84e-2)" "unprognostic (1.63e-2)" "unprognostic (8.07e-2)" "unprognostic (1.18e-2)" "unprognostic (2.25e-2)" "unprognostic (2.82e-2)" "unprognostic (3.81e-1)" "unprognostic (1.64e-1)" "unprognostic (3.84e-2)" "unprognostic (2.95e-3)" "unprognostic (4.92e-2)" "unprognostic (1.88e-2)" "unprognostic (1.58e-2)" "unprognostic (7.76e-2)" "unprognostic (9.83e-3)" "unprognostic (5.73e-2)" "unprognostic (7.54e-2)" "unprognostic (1.57e-1)" RBSN ZFYVE20 ENSG00000131381 "Rabenosyn, RAB effector" Q9H1K0 3 15070073-15099163 "Predicted intracellular proteins" "Protein transport, Transport" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 33.6;Bergmann glia: 50.4;Brain excitatory neurons: 29.9;Brain inhibitory neurons: 31.4;Choroid plexus epithelial cells: 27.4;Distal convoluted tubule cells: 29.4;Ependymal cells: 23.4;Loop of henle epithelial cells: 24.2;Microglia: 28.1;Oligodendrocyte progenitor cells: 28.5;Oligodendrocytes: 35.4;Other brain neurons: 28.6;Papillary tip epithelial cells: 15.5;Podocytes: 29.2;Proximal tubule cells: 23.5;Renal collecting duct intercalated cells: 28.0;Renal collecting duct principal cells: 22.9;Renal connecting tubule cells: 29.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044878 Approved Supported Vesicles NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 65: Brain - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 102: Non-specific - Mixed function" 22 Vesicles "HPA044878: " "unprognostic (2.38e-2)" "unprognostic (4.25e-2)" "unprognostic (9.31e-2)" "unprognostic (3.40e-1)" "unprognostic (1.86e-2)" "unprognostic (4.88e-1)" "unprognostic (1.89e-2)" "unprognostic (7.85e-3)" "potential prognostic unfavorable (2.44e-4)" "potential prognostic favorable (4.26e-5)" "unprognostic (4.41e-3)" "unprognostic (8.47e-2)" "unprognostic (3.58e-3)" "unprognostic (2.37e-2)" "unprognostic (5.54e-3)" "unprognostic (4.80e-2)" "unprognostic (5.22e-2)" "unprognostic (3.65e-2)" "unprognostic (8.04e-3)" "unprognostic (1.87e-1)" "unprognostic (5.38e-2)" "unprognostic (9.69e-2)" "validated prognostic favorable (6.66e-4)" "validated prognostic favorable (8.79e-4)" "unprognostic (1.12e-1)" "unprognostic (6.35e-2)" "unprognostic (1.04e-1)" "unprognostic (7.47e-2)" "unprognostic (5.59e-2)" RBX1 "BA554C12.1, RNF75, ROC1" ENSG00000100387 "Ring-box 1" P62877 22 40951347-40973309 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 1001.3;Extravillous trophoblasts: 811.1;Megakaryocytes: 890.2;Platelets: 1074.8;Syncytiotrophoblasts: 788.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003038 Supported Nucleoplasm NA NA 18000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 97: Non-specific - Cellular respiration" 160 Nucleoplasm "HPA003038: " "unprognostic (8.67e-2)" "unprognostic (3.00e-1)" "unprognostic (9.11e-3)" "potential prognostic favorable (9.47e-5)" "unprognostic (6.18e-2)" "unprognostic (4.32e-3)" "unprognostic (3.30e-1)" "unprognostic (2.09e-1)" "unprognostic (8.00e-3)" "unprognostic (6.40e-2)" "unprognostic (3.11e-2)" "unprognostic (6.45e-3)" "unprognostic (3.98e-2)" "validated prognostic unfavorable (3.75e-5)" "validated prognostic unfavorable (2.18e-6)" "unprognostic (2.40e-2)" "unprognostic (1.58e-1)" "unprognostic (4.18e-3)" "unprognostic (7.53e-2)" "unprognostic (1.49e-2)" "unprognostic (1.31e-1)" "unprognostic (2.62e-3)" "unprognostic (2.41e-2)" "unprognostic (2.63e-1)" "unprognostic (3.73e-1)" "unprognostic (1.11e-1)" "unprognostic (2.63e-1)" "unprognostic (1.02e-2)" "unprognostic (2.50e-1)" "unprognostic (2.64e-1)" "unprognostic (2.39e-2)" RC3H1 "KIAA2025, RNF198, roquin, RP5-1198E17.5" ENSG00000135870 "Ring finger and CCCH-type domains 1" Q5TC82 1 173931084-174022357 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "RNA-binding, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 827.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027428, HPA027434, HPA027448" Approved Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 5: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 24: Neutrophils - Innate immunity signal integration" 135 Cytosol "Golgi apparatus, Plasma membrane" "HPA027428: , HPA027434: , HPA027448: " "unprognostic (1.08e-1)" "unprognostic (4.47e-2)" "unprognostic (4.03e-2)" "unprognostic (2.08e-2)" "unprognostic (1.16e-1)" "unprognostic (5.01e-2)" "unprognostic (2.43e-1)" "unprognostic (6.22e-2)" "unprognostic (1.35e-2)" "unprognostic (6.27e-2)" "potential prognostic favorable (7.00e-5)" "unprognostic (2.22e-3)" "unprognostic (1.66e-1)" "unprognostic (3.74e-2)" "unprognostic (1.05e-1)" "unprognostic (2.59e-1)" "unprognostic (5.98e-2)" "unprognostic (6.28e-2)" "unprognostic (3.76e-2)" "unprognostic (1.70e-1)" "unprognostic (3.38e-1)" "unprognostic (5.44e-2)" "unprognostic (1.34e-2)" "unprognostic (5.92e-2)" "unprognostic (2.98e-2)" "unprognostic (5.18e-2)" "unprognostic (6.93e-2)" "unprognostic (2.67e-1)" "unprognostic (4.81e-1)" "unprognostic (4.49e-3)" "unprognostic (3.49e-2)" RC3H2 "FLJ20301, FLJ20713, MNAB, RNF164" ENSG00000056586 "Ring finger and CCCH-type domains 2" Q9HBD1 9 122844556-122905359 "Enzymes, Predicted intracellular proteins, Transcription factors" "Ubl conjugation pathway" "Repressor, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042863, HPA062144" Approved Enhanced Vesicles NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 40: Non-specific - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Transcription" 67 Vesicles "HPA042863: , HPA062144: " "unprognostic (1.21e-1)" "unprognostic (2.26e-2)" "unprognostic (9.66e-2)" "unprognostic (1.85e-1)" "unprognostic (8.03e-2)" "potential prognostic unfavorable (6.32e-4)" "unprognostic (2.47e-2)" "unprognostic (5.01e-3)" "unprognostic (2.20e-1)" "unprognostic (2.39e-2)" "potential prognostic favorable (3.68e-6)" "unprognostic (2.20e-3)" "unprognostic (1.81e-1)" "unprognostic (3.50e-2)" "unprognostic (3.09e-2)" "unprognostic (8.93e-2)" "potential prognostic unfavorable (2.39e-4)" "unprognostic (7.06e-2)" "unprognostic (8.78e-2)" "unprognostic (1.96e-1)" "unprognostic (1.07e-2)" "unprognostic (1.15e-2)" "unprognostic (5.80e-2)" "unprognostic (2.68e-2)" "unprognostic (3.71e-2)" "unprognostic (6.34e-2)" "unprognostic (3.42e-1)" "unprognostic (7.58e-2)" "unprognostic (2.52e-1)" "unprognostic (5.69e-2)" "unprognostic (5.55e-2)" RCAN1 DSCR1 ENSG00000159200 "Regulator of calcineurin 1" P53805 21 34513142-34615113 "Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 239.5;parathyroid gland: 426.0" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 49.7;Brain inhibitory neurons: 65.2;Breast secretory cells: 46.2;Choroid plexus epithelial cells: 79.0;Distal convoluted tubule cells: 40.3;Loop of henle epithelial cells: 41.1;Oligodendrocyte progenitor cells: 63.6;Oligodendrocytes: 86.1;Other brain neurons: 49.6;Podocytes: 114.6;Proximal tubule cells: 60.7;Renal collecting duct intercalated cells: 56.5;Renal collecting duct principal cells: 58.6;Renal connecting tubule cells: 76.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 209.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "skin cancer: 195.7" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037218, HPA068436" Enhanced Approved Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 27: Non-specific - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 102: Non-specific - Mixed function" 13 Cytosol "CAB037218: , HPA068436: " "unprognostic (7.04e-3)" "unprognostic (1.68e-1)" "unprognostic (1.76e-1)" "unprognostic (9.72e-2)" "unprognostic (8.42e-2)" "unprognostic (1.45e-1)" "unprognostic (5.58e-2)" "potential prognostic unfavorable (9.22e-4)" "unprognostic (1.77e-1)" "unprognostic (1.18e-1)" "potential prognostic favorable (5.64e-5)" "unprognostic (1.91e-3)" "unprognostic (2.68e-3)" "unprognostic (1.52e-2)" "unprognostic (2.72e-3)" "unprognostic (3.11e-1)" "unprognostic (2.04e-2)" "unprognostic (1.76e-1)" "unprognostic (3.76e-2)" "unprognostic (2.30e-2)" "unprognostic (6.78e-3)" "unprognostic (1.60e-1)" "unprognostic (3.82e-1)" "unprognostic (3.63e-1)" "unprognostic (8.89e-2)" "unprognostic (5.99e-3)" "unprognostic (1.13e-1)" "unprognostic (1.18e-2)" "unprognostic (2.80e-1)" "unprognostic (8.60e-3)" "unprognostic (1.23e-2)" RCAN2 "DSCR1L1, ZAKI-4" ENSG00000172348 "Regulator of calcineurin 2" Q14206 6 46220736-46491972 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 194.4;heart muscle: 186.7;tongue: 168.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 1680.4;Myonuclei: 1221.5;Pericytes: 421.2;Renal collecting duct intercalated cells: 1641.3;Salivary ionocytes: 883.0;Thymic myoid cells: 558.8;Thyrotrophs: 548.3;Vascular smooth muscle cells: 1220.1" "Cell type enhanced" "Detected in all" "vascular associated smooth muscle cell: 2187.2" "Group enriched" "Detected in all" 5 "Kidney Chromophobe (TCGA): 116.1;Kidney Renal Clear Cell Carcinoma (TCGA): 46.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 16 "gdT-cell: 1.7;memory CD4 T-cell: 1.1;memory CD8 T-cell: 2.1;naive CD8 T-cell: 1.5" "Lineage enriched" "Detected in single" 21 "T-cells: 2.1" "Cancer enhanced" "Detected in many" "lymphoma: 12.2" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Breast - Endothelial cells, Lung - Smooth muscle cells, Testis - Peritubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053880 Uncertain Approved "Nucleoplasm,Vesicles,Microtubules,Primary cilium,Mitochondria" NA NA "Cluster 27: T-cells - Unknown function" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 62: Smooth muscle cells - Muscle contraction" 1 Mitochondria "Nucleoplasm, Vesicles, Microtubules, Primary cilium" "HPA053880: " "unprognostic (5.09e-2)" "unprognostic (4.04e-1)" "unprognostic (3.15e-1)" "unprognostic (3.18e-2)" "unprognostic (6.93e-2)" "unprognostic (8.70e-2)" "unprognostic (3.94e-3)" "unprognostic (1.81e-1)" "unprognostic (5.25e-2)" "unprognostic (3.73e-2)" "validated prognostic favorable (5.67e-9)" "validated prognostic favorable (4.86e-4)" "unprognostic (5.54e-2)" "unprognostic (2.43e-3)" "unprognostic (5.77e-2)" "potential prognostic favorable (2.65e-4)" "unprognostic (4.84e-2)" "unprognostic (1.61e-2)" "unprognostic (3.03e-2)" "unprognostic (3.08e-1)" "unprognostic (3.67e-2)" "potential prognostic favorable (1.05e-4)" "unprognostic (1.61e-2)" "unprognostic (8.23e-2)" "potential prognostic unfavorable (2.72e-4)" "unprognostic (4.64e-2)" "unprognostic (3.41e-1)" "unprognostic (2.29e-2)" "unprognostic (8.80e-2)" "unprognostic (6.71e-2)" "unprognostic (4.99e-2)" RCAN3 DSCR1L2 ENSG00000117602 "RCAN family member 3" Q9UKA8 1 24502351-24541040 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 31.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 173.5;Endometrial ciliated cells: 178.6;Fallopian tube ciliated cells: 218.0;Ocular epithelial cells: 167.7;Prostatic glandular cells: 377.8;Respiratory ciliated cells: 194.2;T-cells: 168.1" "Cell type enhanced" "Detected in many" "leukocyte: 90.2;upper rhombic lip: 84.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 38.3" "Lineage enriched" "Detected in all" 7 "T-cells: 38.3" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Prostate - Prostate glandular cells, Spleen - B-cells (Spleen), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 213.2" "HPA034533, HPA064289" Enhanced Approved "Nucleoli fibrillar center,Nuclear speckles" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 9: T-cells - Adaptive immunity: Regulation" 12 "Nuclear speckles" "Nucleoli fibrillar center" "HPA034533: , HPA064289: " "unprognostic (6.10e-2)" "unprognostic (1.14e-1)" "unprognostic (2.71e-1)" "unprognostic (9.72e-3)" "unprognostic (3.48e-2)" "unprognostic (1.62e-1)" "unprognostic (1.72e-1)" "unprognostic (2.47e-2)" "unprognostic (2.19e-3)" "unprognostic (3.18e-2)" "potential prognostic favorable (5.46e-5)" "unprognostic (3.71e-2)" "unprognostic (3.41e-1)" "potential prognostic unfavorable (1.38e-4)" "unprognostic (1.82e-2)" "unprognostic (1.81e-1)" "unprognostic (2.26e-1)" "unprognostic (8.22e-2)" "unprognostic (8.98e-2)" "unprognostic (1.27e-1)" "unprognostic (3.82e-1)" "unprognostic (2.78e-2)" "unprognostic (1.05e-1)" "unprognostic (2.86e-1)" "unprognostic (2.77e-2)" "unprognostic (4.52e-1)" "unprognostic (2.28e-1)" "unprognostic (2.73e-1)" "unprognostic (2.92e-1)" "unprognostic (4.58e-2)" "unprognostic (1.85e-2)" RCBTB1 "CLLD7, CLLL7, FLJ10716" ENSG00000136144 "RCC1 and BTB domain containing protein 1" Q8NDN9 13 49531946-49585558 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation" "Chromatin regulator" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 147.0;Oligodendrocyte progenitor cells: 106.8;Oligodendrocytes: 94.1;Rod photoreceptor cells: 125.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056783 Approved Nucleoplasm NA NA "Cluster 32: Basophils - Transcription" "Cluster 65: Brain - Transcription" "Cluster 19: Astrocytes - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 79: Photoreceptor cells - Phototransduction" 2 Nucleoplasm "HPA056783: " "unprognostic (4.25e-2)" "unprognostic (1.16e-1)" "unprognostic (1.44e-2)" "unprognostic (3.89e-1)" "unprognostic (4.76e-1)" "unprognostic (1.27e-2)" "unprognostic (6.74e-2)" "unprognostic (3.49e-2)" "unprognostic (1.54e-1)" "unprognostic (3.80e-2)" "potential prognostic favorable (4.07e-5)" "unprognostic (4.19e-3)" "potential prognostic favorable (5.49e-4)" "unprognostic (3.41e-2)" "unprognostic (2.99e-1)" "unprognostic (4.72e-3)" "unprognostic (8.77e-2)" "unprognostic (2.53e-2)" "unprognostic (3.42e-2)" "potential prognostic unfavorable (8.88e-4)" "unprognostic (4.91e-3)" "unprognostic (5.35e-3)" "unprognostic (3.81e-1)" "unprognostic (1.91e-1)" "unprognostic (1.78e-1)" "unprognostic (1.99e-3)" "unprognostic (2.43e-1)" "unprognostic (2.41e-1)" "unprognostic (2.07e-1)" "unprognostic (3.84e-1)" "unprognostic (9.77e-2)" RCBTB2 CHC1L ENSG00000136161 "RCC1 and BTB domain containing protein 2" O95199 13 48488963-48533256 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglia: 164.0;Neutrophils: 101.2;Thymocytes: 163.5" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 208.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Leukemia: 26.4" "Breast - T-cells, Kidney - Fibroblasts, Minor Salivary Gland - Minor salivary gland ductal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040242 Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 21: Non-specific - Metabolism" "Cluster 59: Leukemia - T-cell receptor" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 28 "Nucleoplasm, Golgi apparatus" "HPA040242: " "unprognostic (3.35e-3)" "unprognostic (6.00e-2)" "unprognostic (6.91e-2)" "unprognostic (2.05e-1)" "unprognostic (3.95e-1)" "unprognostic (1.21e-1)" "unprognostic (1.23e-1)" "unprognostic (7.21e-2)" "unprognostic (7.87e-3)" "unprognostic (1.62e-1)" "potential prognostic favorable (3.83e-9)" "unprognostic (2.04e-3)" "potential prognostic favorable (1.80e-5)" "unprognostic (1.22e-1)" "unprognostic (8.35e-3)" "unprognostic (1.53e-3)" "unprognostic (1.79e-2)" "unprognostic (3.64e-2)" "unprognostic (3.74e-1)" "unprognostic (6.35e-2)" "unprognostic (2.71e-2)" "unprognostic (2.30e-1)" "unprognostic (8.75e-2)" "unprognostic (1.87e-1)" "unprognostic (2.59e-1)" "unprognostic (3.00e-3)" "unprognostic (2.16e-3)" "unprognostic (2.18e-2)" "unprognostic (9.97e-2)" "unprognostic (4.89e-2)" "unprognostic (1.42e-2)" RCC1 CHC1 ENSG00000180198 "Regulator of chromosome condensation 1" P18754 1 28505943-28539300 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "DNA-binding, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Late spermatids: 1378.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Stomach - Mitotic cells (Stomach), Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015413, HPA027573, HPA027574" Enhanced Enhanced Nucleoplasm NA NA 57000 "Cluster 22: Eosinophils - Transcription" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 12: Non-specific - Vasculature" "Cluster 37: Non-specific - mRNA processing" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 39 Nucleoplasm "CAB015413: , HPA027573: , HPA027574: " "unprognostic (2.15e-1)" "unprognostic (4.93e-2)" "unprognostic (5.33e-2)" "unprognostic (4.24e-2)" "unprognostic (2.94e-2)" "unprognostic (3.10e-1)" "unprognostic (1.99e-1)" "potential prognostic favorable (9.24e-4)" "unprognostic (4.14e-2)" "unprognostic (2.26e-3)" "validated prognostic unfavorable (9.65e-5)" "validated prognostic unfavorable (3.04e-4)" "potential prognostic unfavorable (4.03e-4)" "validated prognostic unfavorable (8.45e-8)" "validated prognostic unfavorable (4.66e-7)" "unprognostic (2.35e-2)" "potential prognostic unfavorable (3.54e-4)" "unprognostic (3.38e-1)" "unprognostic (2.71e-2)" "unprognostic (1.80e-1)" "unprognostic (2.58e-1)" "unprognostic (1.59e-2)" "unprognostic (1.18e-1)" "potential prognostic unfavorable (5.13e-4)" "unprognostic (8.77e-3)" "unprognostic (3.09e-2)" "unprognostic (1.88e-3)" "unprognostic (4.11e-2)" "unprognostic (3.62e-1)" "unprognostic (6.23e-2)" "unprognostic (1.40e-2)" RCC1L WBSCR16 ENSG00000274523 "RCC1 like" Q96I51 7 75027122-75074228 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor, RNA-binding, rRNA-binding" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060643 Approved NA NA "Cluster 41: Basophils - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 39 "HPA060643: " "unprognostic (7.10e-2)" "unprognostic (2.71e-1)" "unprognostic (1.18e-1)" "unprognostic (2.72e-1)" "unprognostic (6.03e-3)" "unprognostic (2.25e-3)" "unprognostic (7.42e-2)" "unprognostic (2.89e-2)" "unprognostic (3.34e-2)" "unprognostic (2.34e-1)" "unprognostic (4.87e-2)" "potential prognostic unfavorable (4.94e-5)" "unprognostic (1.24e-2)" "unprognostic (2.81e-2)" "unprognostic (1.31e-1)" "unprognostic (2.45e-1)" "unprognostic (3.80e-1)" "unprognostic (6.69e-3)" "unprognostic (8.06e-2)" "unprognostic (4.89e-2)" "unprognostic (2.68e-1)" "unprognostic (2.49e-1)" "unprognostic (3.26e-1)" "unprognostic (2.01e-1)" "unprognostic (1.27e-1)" "unprognostic (3.46e-2)" RCC2 TD-60 ENSG00000179051 "Regulator of chromosome condensation 2" Q9P258 1 17406760-17439677 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 20.8;Late spermatids: 22.0;Microglia: 86.5;Oligodendrocyte progenitor cells: 33.6;Oligodendrocytes: 27.5;Papillary tip epithelial cells: 25.7;Proximal tubule cells: 19.8;Renal collecting duct principal cells: 32.9;Renal connecting tubule cells: 29.5" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 109.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Spleen - B-cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072281 Approved NA NA 59000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 18: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 102: Non-specific - Mixed function" 14 "HPA072281: " "unprognostic (3.23e-2)" "unprognostic (1.31e-1)" "unprognostic (1.19e-1)" "unprognostic (1.95e-2)" "unprognostic (1.28e-1)" "unprognostic (1.39e-1)" "unprognostic (3.87e-1)" "potential prognostic favorable (6.40e-4)" "unprognostic (1.58e-1)" "unprognostic (2.48e-1)" "unprognostic (5.88e-2)" "unprognostic (7.97e-2)" "unprognostic (7.69e-2)" "validated prognostic unfavorable (3.28e-7)" "validated prognostic unfavorable (5.05e-4)" "unprognostic (1.11e-2)" "unprognostic (3.17e-3)" "unprognostic (8.92e-2)" "unprognostic (5.93e-2)" "unprognostic (5.31e-2)" "unprognostic (1.79e-1)" "unprognostic (1.39e-2)" "unprognostic (1.29e-1)" "unprognostic (1.05e-1)" "unprognostic (2.87e-1)" "unprognostic (3.73e-3)" "unprognostic (1.99e-3)" "unprognostic (3.28e-2)" "unprognostic (4.06e-1)" "unprognostic (1.33e-1)" "unprognostic (2.28e-1)" RCCD1 MGC14386 ENSG00000166965 "RCC1 domain containing 1" A6NED2 15 90954881-90963125 "Predicted intracellular proteins" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oocytes: 96.7;Retinal pigment epithelial cells: 42.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039683, HPA040776" Enhanced Enhanced "Plasma membrane,Cytosol" NA Yes "Cluster 33: Non-specific - ATP binding" "Cluster 64: Non-specific - Transcription" "Cluster 5: Non-specific - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 27: Non-specific - Cell proliferation" 28 "Plasma membrane, Cytosol" "HPA039683: , HPA040776: " "unprognostic (1.02e-3)" "unprognostic (8.91e-2)" "unprognostic (1.42e-1)" "unprognostic (1.21e-1)" "unprognostic (5.95e-3)" "unprognostic (3.62e-1)" "unprognostic (9.87e-3)" "unprognostic (2.52e-3)" "unprognostic (6.15e-2)" "unprognostic (5.71e-3)" "unprognostic (1.24e-1)" "unprognostic (8.08e-2)" "unprognostic (4.53e-2)" "unprognostic (5.43e-2)" "potential prognostic unfavorable (2.26e-4)" "unprognostic (1.29e-3)" "unprognostic (2.25e-2)" "unprognostic (6.79e-2)" "unprognostic (5.15e-3)" "unprognostic (1.16e-2)" "unprognostic (1.05e-2)" "unprognostic (1.44e-2)" "unprognostic (1.27e-1)" "unprognostic (1.50e-1)" "unprognostic (3.87e-3)" "unprognostic (2.27e-1)" "unprognostic (9.08e-3)" "unprognostic (2.54e-3)" "unprognostic (1.13e-1)" "unprognostic (6.70e-2)" "unprognostic (8.19e-2)" RCE1 "FACE-2, FACE2, hRCE1, RCE1A, RCE1B" ENSG00000173653 "Ras converting CAAX endopeptidase 1" Q9Y256 11 66842835-66846552 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 62.0;Esophageal apical cells: 53.3;Extravillous trophoblasts: 81.3;Migrating cytotrophoblasts: 65.8;Syncytiotrophoblasts: 65.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074124 Approved NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 64: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 24: Non-specific - Unknown function" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 1 "HPA074124: " "unprognostic (3.06e-2)" "unprognostic (4.41e-3)" "unprognostic (1.63e-2)" "unprognostic (1.63e-1)" "unprognostic (1.15e-1)" "unprognostic (9.50e-3)" "unprognostic (6.44e-2)" "unprognostic (1.23e-2)" "unprognostic (6.69e-3)" "unprognostic (1.37e-1)" "unprognostic (4.74e-2)" "unprognostic (9.32e-2)" "unprognostic (8.11e-2)" "unprognostic (8.22e-3)" "unprognostic (4.69e-2)" "potential prognostic unfavorable (9.00e-4)" "unprognostic (1.13e-3)" "unprognostic (2.86e-1)" "unprognostic (2.47e-2)" "unprognostic (1.85e-2)" "unprognostic (3.67e-2)" "unprognostic (3.13e-3)" "unprognostic (9.85e-3)" "unprognostic (2.13e-2)" "unprognostic (4.11e-3)" "unprognostic (7.07e-2)" "unprognostic (2.63e-1)" "unprognostic (6.58e-3)" "unprognostic (1.14e-1)" "unprognostic (1.02e-1)" "unprognostic (9.72e-2)" RCHY1 "ARNIP, CHIMP, DKFZp586C1620, PIRH2, PRO1996, RNF199, ZCHY, ZNF363" ENSG00000163743 "Ring finger and CHY zinc finger domain containing 1" Q96PM5 4 75479033-75514764 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 28.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030338, HPA030339" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 49 Cytosol "Nucleoplasm, Vesicles" "HPA030338: , HPA030339: " "unprognostic (9.13e-2)" "unprognostic (1.96e-1)" "unprognostic (9.11e-2)" "unprognostic (1.75e-2)" "unprognostic (2.95e-2)" "unprognostic (9.22e-2)" "unprognostic (3.46e-2)" "unprognostic (6.12e-2)" "unprognostic (6.77e-3)" "unprognostic (6.48e-2)" "validated prognostic favorable (2.04e-7)" "validated prognostic favorable (2.18e-5)" "unprognostic (6.53e-3)" "unprognostic (1.14e-2)" "unprognostic (9.23e-2)" "unprognostic (1.60e-1)" "unprognostic (6.39e-2)" "unprognostic (8.62e-2)" "unprognostic (2.04e-1)" "unprognostic (4.78e-2)" "unprognostic (2.31e-1)" "unprognostic (5.01e-3)" "unprognostic (1.15e-2)" "unprognostic (7.79e-2)" "unprognostic (2.93e-3)" "unprognostic (1.73e-2)" "unprognostic (3.18e-1)" "unprognostic (3.42e-1)" "unprognostic (3.31e-1)" "unprognostic (9.69e-2)" "unprognostic (1.60e-1)" RCL1 "RNAC, RPCL1" ENSG00000120158 "RNA terminal phosphate cyclase like 1" Q9Y2P8 9 4792944-4885917 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 229.4" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 223.3;Hepatocytes: 317.7;Myonuclei: 265.0;Pancreatic acinar cells: 265.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071308 Approved Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 18 Nucleoplasm "HPA071308: " "unprognostic (1.22e-1)" "unprognostic (1.17e-2)" "unprognostic (1.75e-1)" "unprognostic (3.35e-2)" "unprognostic (1.71e-1)" "unprognostic (9.53e-2)" "unprognostic (4.82e-3)" "unprognostic (2.71e-3)" "unprognostic (1.38e-1)" "unprognostic (1.53e-2)" "potential prognostic favorable (9.86e-5)" "unprognostic (4.20e-3)" "unprognostic (4.11e-2)" "validated prognostic favorable (6.76e-5)" "validated prognostic favorable (4.81e-4)" "unprognostic (1.51e-2)" "unprognostic (1.52e-2)" "unprognostic (3.07e-2)" "unprognostic (4.87e-2)" "unprognostic (5.34e-2)" "unprognostic (6.03e-2)" "unprognostic (9.51e-3)" "unprognostic (1.67e-2)" "potential prognostic unfavorable (6.88e-4)" "unprognostic (1.67e-1)" "unprognostic (2.08e-3)" "unprognostic (2.33e-1)" "unprognostic (3.02e-1)" "unprognostic (8.49e-2)" "unprognostic (4.20e-2)" "unprognostic (8.92e-3)" RCN1 "FLJ37041, PIG20, Rcal, RCN" ENSG00000049449 "Reticulocalbin 1" Q15293 11 32091074-32105722 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "epididymis: 623.3" "Cell type enriched" "Detected in many" 4 "Epididymal principal cells: 1324.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Somatotropes, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038474, HPA062104" Approved Supported "Endoplasmic reticulum" "Intracellular and membrane" "No annotated function" NA NA 3100000 "Cluster 33: Non-specific - ATP binding" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 21: Non-specific - Metabolism" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 41 "Endoplasmic reticulum" "HPA038474: , HPA062104: " "unprognostic (2.18e-1)" "unprognostic (1.87e-1)" "unprognostic (7.97e-2)" "unprognostic (5.91e-2)" "unprognostic (7.12e-2)" "unprognostic (5.21e-3)" "unprognostic (2.93e-2)" "unprognostic (3.50e-3)" "unprognostic (3.59e-2)" "unprognostic (1.28e-1)" "unprognostic (1.74e-2)" "unprognostic (1.28e-2)" "unprognostic (8.55e-3)" "potential prognostic unfavorable (7.97e-4)" "unprognostic (1.37e-3)" "validated prognostic unfavorable (6.12e-5)" "validated prognostic unfavorable (3.74e-5)" "unprognostic (4.04e-2)" "unprognostic (2.26e-2)" "unprognostic (5.34e-2)" "unprognostic (7.38e-2)" "unprognostic (5.43e-2)" "unprognostic (2.67e-2)" "unprognostic (4.43e-2)" "unprognostic (4.02e-2)" "unprognostic (1.88e-1)" "unprognostic (1.85e-1)" "unprognostic (1.66e-2)" "unprognostic (2.70e-1)" "unprognostic (2.69e-2)" "unprognostic (5.15e-2)" RCN2 "E6BP, ERC-55, ERC55, TCBP49" ENSG00000117906 "Reticulocalbin 2" Q14257 15 76931738-76954393 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 303.6" "Cell type enhanced" "Detected in all" "Early primary spermatocytes: 467.4;Epididymal principal cells: 821.8;Extravillous trophoblasts: 376.8;Late primary spermatocytes: 428.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030694, HPA030695" Enhanced Supported Enhanced "Endoplasmic reticulum" "Intracellular and membrane" "No annotated function" NA NA 24000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 22: Epididymis - Mixed function" "Cluster 14: Neurons - Synaptic function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 32 "Endoplasmic reticulum" "HPA030694: , HPA030695: " "unprognostic (1.09e-1)" "unprognostic (9.53e-3)" "unprognostic (1.33e-1)" "unprognostic (1.49e-1)" "unprognostic (7.12e-2)" "unprognostic (8.07e-2)" "unprognostic (3.10e-1)" "unprognostic (3.87e-2)" "unprognostic (5.88e-2)" "unprognostic (1.10e-2)" "unprognostic (1.02e-3)" "unprognostic (5.75e-2)" "unprognostic (1.22e-1)" "validated prognostic unfavorable (9.27e-5)" "validated prognostic unfavorable (5.25e-6)" "unprognostic (1.02e-1)" "unprognostic (8.97e-2)" "unprognostic (1.07e-2)" "unprognostic (1.53e-2)" "unprognostic (1.30e-2)" "unprognostic (2.73e-1)" "unprognostic (5.38e-2)" "unprognostic (1.59e-3)" "unprognostic (1.73e-1)" "unprognostic (4.77e-2)" "unprognostic (2.79e-1)" "unprognostic (1.68e-2)" "unprognostic (2.49e-1)" "unprognostic (3.54e-1)" "unprognostic (8.09e-2)" "unprognostic (2.29e-2)" RCN3 RLP49 ENSG00000142552 "Reticulocalbin 3" Q96D15 19 49528003-49546962 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 108.4;Endometrial stromal cells: 46.0;Fibroblasts: 80.8;Hepatic stellate cells: 251.7;Hofbauer cells: 44.8;Oocytes: 55.3;Ovarian stromal cells: 44.5;Peritubular myoid cells: 41.6" "Group enriched" "Detected in many" 4 "astrocyte: 6.4;central nervous system macrophage: 21.7;fibroblast: 22.3;vascular associated smooth muscle cell: 15.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 6.9" "Group enriched" "Detected in many" 9 "granulocytes: 2.6;NK-cells: 1.8;T-cells: 6.9" "Cancer enhanced" "Detected in all" "Bone cancer: 127.6;Sarcoma: 142.8" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Heart muscle - Fibroblasts, Lung - Fibroblasts_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043134, HPA050402" Uncertain Supported "Endoplasmic reticulum,Vesicles" "Intracellular and membrane" Transport No No 3800000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 12: Non-specific - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 9 "Endoplasmic reticulum" Vesicles "HPA043134: , HPA050402: " "potential prognostic favorable (7.80e-4)" "unprognostic (2.14e-1)" "unprognostic (1.20e-1)" "unprognostic (1.15e-1)" "unprognostic (1.19e-3)" "unprognostic (6.13e-2)" "unprognostic (7.26e-3)" "unprognostic (5.47e-2)" "unprognostic (1.23e-1)" "unprognostic (7.52e-2)" "potential prognostic unfavorable (7.65e-5)" "unprognostic (8.41e-2)" "unprognostic (4.63e-2)" "potential prognostic unfavorable (9.55e-4)" "unprognostic (2.79e-2)" "unprognostic (4.23e-2)" "unprognostic (2.81e-3)" "unprognostic (1.12e-1)" "unprognostic (1.72e-1)" "unprognostic (6.08e-2)" "unprognostic (2.69e-2)" "unprognostic (1.81e-1)" "unprognostic (1.84e-1)" "unprognostic (2.14e-1)" "unprognostic (8.67e-3)" "unprognostic (3.05e-2)" "unprognostic (7.06e-2)" "unprognostic (9.48e-2)" "unprognostic (2.07e-1)" "unprognostic (4.78e-3)" "unprognostic (7.05e-3)" RCOR1 "COREST, KIAA0071, RCOR" ENSG00000089902 "REST corepressor 1" Q9UKL0 14 102592649-102730561 "Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 645.2;Neutrophil progenitors: 998.0;Neutrophils: 805.3;Suprabasal keratinocytes: 525.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001956, HPA049327, HPA054241" Supported Enhanced Nucleoplasm NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 35: Non-specific - DNA binding" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 100 Nucleoplasm "CAB001956: , HPA049327: , HPA054241: " "unprognostic (2.25e-1)" "unprognostic (2.15e-1)" "unprognostic (2.10e-1)" "unprognostic (5.37e-2)" "unprognostic (2.00e-2)" "unprognostic (2.13e-2)" "unprognostic (2.10e-2)" "unprognostic (3.24e-2)" "unprognostic (3.70e-1)" "unprognostic (1.00e-2)" "potential prognostic favorable (1.44e-5)" "unprognostic (2.47e-2)" "unprognostic (4.53e-1)" "unprognostic (3.14e-3)" "unprognostic (5.26e-2)" "unprognostic (3.01e-3)" "unprognostic (2.09e-2)" "unprognostic (3.42e-2)" "unprognostic (3.14e-2)" "unprognostic (6.82e-2)" "unprognostic (2.43e-2)" "unprognostic (1.59e-2)" "unprognostic (3.60e-3)" "unprognostic (9.72e-3)" "unprognostic (2.96e-1)" "unprognostic (2.33e-2)" "unprognostic (2.07e-2)" "unprognostic (1.87e-1)" "unprognostic (2.89e-1)" "unprognostic (5.66e-2)" "unprognostic (5.88e-2)" RCOR2 ENSG00000167771 "REST corepressor 2" Q8IZ40 11 63911230-63917164 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 6.2" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 10.6;Extravillous trophoblasts: 7.2;Megakaryocytes: 6.2;Neuroendocrine cells: 6.5;Retinal bipolar cells: 24.6;Syncytiotrophoblasts: 6.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 38.1" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021638 Uncertain Approved Nucleoplasm,Vesicles,Midbody Yes NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 17 Nucleoplasm "Vesicles, Midbody" "HPA021638: " "unprognostic (6.26e-2)" "unprognostic (1.60e-2)" "unprognostic (9.48e-2)" "unprognostic (5.88e-2)" "unprognostic (2.26e-1)" "unprognostic (7.13e-2)" "unprognostic (1.26e-2)" "unprognostic (1.28e-3)" "unprognostic (3.38e-2)" "unprognostic (1.98e-2)" "unprognostic (5.20e-2)" "unprognostic (1.93e-2)" "unprognostic (2.98e-2)" "unprognostic (7.80e-2)" "unprognostic (6.33e-2)" "unprognostic (1.33e-1)" "unprognostic (2.85e-1)" "unprognostic (2.50e-1)" "unprognostic (3.02e-1)" "unprognostic (1.70e-2)" "unprognostic (1.12e-1)" "unprognostic (2.06e-1)" "unprognostic (2.66e-1)" "unprognostic (2.94e-2)" RCOR3 FLJ10876 ENSG00000117625 "REST corepressor 3" Q9P2K3 1 211258377-211316385 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Myonuclei: 540.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007413, HPA007621, HPA071997" Enhanced Enhanced Nucleoplasm,Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 55: Myocytes - Oxidative muscle function" 53 Nucleoplasm Cytosol "HPA007413: , HPA007621: , HPA071997: " "unprognostic (2.24e-2)" "unprognostic (1.06e-1)" "unprognostic (1.20e-1)" "unprognostic (1.42e-1)" "unprognostic (2.71e-1)" "unprognostic (4.47e-2)" "unprognostic (5.50e-3)" "unprognostic (6.08e-2)" "unprognostic (2.65e-1)" "unprognostic (8.24e-3)" "potential prognostic favorable (8.47e-4)" "unprognostic (2.90e-2)" "unprognostic (3.21e-2)" "unprognostic (1.16e-2)" "unprognostic (9.57e-2)" "unprognostic (8.79e-2)" "unprognostic (3.40e-1)" "unprognostic (3.15e-1)" "unprognostic (7.08e-2)" "unprognostic (2.40e-2)" "unprognostic (1.34e-2)" "unprognostic (2.40e-1)" "unprognostic (2.49e-2)" "unprognostic (8.79e-2)" "unprognostic (7.61e-2)" "unprognostic (1.07e-1)" "unprognostic (1.42e-1)" "unprognostic (1.52e-2)" "unprognostic (1.54e-1)" "unprognostic (1.85e-1)" "unprognostic (3.86e-1)" RCSD1 "CapZIP, MGC21854, MK2S4" ENSG00000198771 "RCSD domain containing 1" Q6JBY9 1 167630093-167708696 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 107.6;skeletal muscle: 138.5" "Cell type enhanced" "Detected in many" "B-cells: 558.0;Hematopoietic stem cells: 539.1;Innate lymphoid cells: 186.2;Kupffer cells: 346.4;Macrophages: 186.8;Microglia: 389.0;Monocyte progenitors: 244.7;monocytes: 186.2;Myonuclei: 166.0;Neutrophil progenitors: 377.2;Neutrophils: 307.5;NK-cells: 184.8;T-cells: 194.3;Thymocytes: 482.8" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 482.3;endothelial cell: 207.2;leukocyte: 311.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 15 "Leukemia: 131.2;lymphoma: 150.1;Myeloma: 96.7" "Colon - T-cells, Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016597 Enhanced NA NA 150000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 6: Leukemia - Signal transduction" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 4 "HPA016597: " "unprognostic (1.92e-2)" "unprognostic (5.78e-2)" "unprognostic (7.21e-2)" "unprognostic (1.79e-2)" "unprognostic (1.18e-1)" "unprognostic (2.97e-1)" "unprognostic (3.28e-1)" "unprognostic (1.70e-1)" "unprognostic (1.72e-3)" "unprognostic (5.44e-2)" "potential prognostic favorable (5.41e-5)" "unprognostic (6.37e-2)" "unprognostic (3.13e-2)" "unprognostic (1.53e-1)" "unprognostic (4.56e-2)" "potential prognostic favorable (6.05e-5)" "unprognostic (1.89e-1)" "unprognostic (1.69e-1)" "unprognostic (2.71e-1)" "unprognostic (2.22e-1)" "unprognostic (2.44e-1)" "unprognostic (1.82e-1)" "unprognostic (1.52e-1)" "unprognostic (1.20e-1)" "unprognostic (3.62e-2)" "unprognostic (2.96e-1)" "unprognostic (3.97e-1)" "unprognostic (9.35e-2)" "unprognostic (2.31e-2)" "unprognostic (4.36e-1)" "unprognostic (2.40e-1)" RCVRN RCV1 ENSG00000109047 Recoverin P35243 17 9896320-9905271 "Plasma proteins, Predicted intracellular proteins, Transporters" "Sensory transduction, Vision" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 204 "retina: 430.9" "Group enriched" "Detected in some" 17 "Cone photoreceptor cells: 619.0;Rod photoreceptor cells: 1774.6" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Rhabdoid: 1.3" "Region enhanced" "Detected in single" "hippocampal formation: 1.3" "Low region specificity" "Detected in many" "HPA015783, CAB022363" Enhanced Approved "Mid piece,Principal piece" NA NA "Cluster 42: Retina - Visual perception" "Cluster 53: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 79: Photoreceptor cells - Phototransduction" "Mid piece, Principal piece" "CAB022363: , HPA015783: " "unprognostic (2.72e-3)" RD3 "C1orf36, LCA12" ENSG00000198570 "RD3 regulator of GUCY2D" Q7Z3Z2 1 211476522-211492162 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Leber congenital amaurosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 27 "retina: 43.8" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 265.0;Mast cells: 53.4;Retinal bipolar cells: 185.0;Rod photoreceptor cells: 176.1" "Cell type enhanced" "Detected in some" "deep-layer near-projecting: 3.9;eccentric medium spiny neuron: 8.3" "Cancer enhanced" "Detected in single" "Testicular Germ Cell Tumor (TCGA): 1.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 5.7;Uterine cancer: 2.1" "Adrenal gland - Adrenal medulla cells, Pituitary gland - Thyrotropes, Prostate - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA029941, HPA029943" Enhanced NA NA "Cluster 42: Retina - Visual perception" "Cluster 48: Non-specific - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 5 "HPA029941: , HPA029943: " "unprognostic (1.30e-1)" RD3L "TDRD9-AS1, TDRD9AS1" ENSG00000227729 "RD3 like" P0DJH9 14 103940426-103942561 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 31 "heart muscle: 21.8;retina: 12.4" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 29.0;Platelets: 19.8;Retinal amacrine cells: 73.8;Retinal bipolar cells: 65.0;Retinal ganglion cells: 7.7;Retinal horizontal cells: 22.0;Retinal pigment epithelial cells: 12.8;Rod photoreceptor cells: 8.5" "Cell type enriched" "Detected in single" 5 "midbrain-derived inhibitory: 4.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes" "Region enhanced" "Detected in many" "olfactory bulb: 10.4" "Group enriched" "Detected in many" 10 "basal ganglia: 1.8;midbrain: 2.5;olfactory bulb: 1.8;pons: 2.3;thalamus: 5.2" HPA067971 Enhanced NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "HPA067971: " RDH10 SDR16C4 ENSG00000121039 "Retinol dehydrogenase 10" Q8IZV5 8 73294602-73325281 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 565.0;Müller glia: 335.4;Respiratory deuterosomal cells: 244.6;Respiratory secretory cells: 285.6;Retinal pigment epithelial cells: 920.8;Salivary duct cells: 569.2" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 45.5;fibroblast: 39.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049199 Supported "Lipid droplets" NA NA "Cluster 42: Retina - Visual perception" "Cluster 12: Non-specific - Vasculature" "Cluster 72: Neuronal - Signal transduction" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" 6 "Lipid droplets" "HPA049199: " "unprognostic (1.60e-2)" "unprognostic (2.14e-1)" "unprognostic (1.36e-2)" "unprognostic (2.29e-1)" "unprognostic (4.04e-1)" "potential prognostic unfavorable (6.07e-6)" "potential prognostic unfavorable (9.23e-4)" "unprognostic (1.76e-1)" "unprognostic (1.70e-2)" "unprognostic (7.91e-2)" "potential prognostic favorable (1.65e-5)" "unprognostic (2.47e-2)" "unprognostic (1.25e-3)" "unprognostic (1.46e-1)" "unprognostic (1.20e-1)" "unprognostic (1.24e-1)" "unprognostic (1.77e-2)" "unprognostic (2.98e-2)" "unprognostic (2.09e-2)" "unprognostic (3.40e-1)" "unprognostic (1.46e-2)" "potential prognostic unfavorable (1.17e-4)" "unprognostic (3.78e-2)" "unprognostic (4.68e-2)" "unprognostic (1.30e-1)" "unprognostic (3.69e-1)" "unprognostic (1.46e-2)" "unprognostic (3.78e-2)" "unprognostic (2.46e-2)" "unprognostic (1.40e-3)" "unprognostic (7.22e-2)" RDH11 "ARSDR1, MDT1, SDR7C1" ENSG00000072042 "Retinol dehydrogenase 11" Q8TC12 14 67676800-67695793 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Cataract, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "prostate: 546.2" "Cell type enhanced" "Detected in many" "Platelets: 46.5;Prostatic glandular cells: 149.2;Retinal pigment epithelial cells: 59.7" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 5 "Prostate Adenocarcinoma (TCGA): 998.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells, Stomach - Mitotic cells (Stomach), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB046011 Enhanced "Intracellular and membrane" Enzyme NA NA 180000 "Cluster 41: Basophils - Unknown function" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 41 "CAB046011: " "unprognostic (3.35e-1)" "unprognostic (2.96e-1)" "unprognostic (1.10e-2)" "unprognostic (5.15e-3)" "unprognostic (3.70e-1)" "unprognostic (1.29e-1)" "unprognostic (1.99e-2)" "unprognostic (1.54e-1)" "potential prognostic unfavorable (9.75e-5)" "unprognostic (1.00e-1)" "potential prognostic favorable (2.74e-6)" "unprognostic (3.78e-3)" "unprognostic (3.65e-3)" "unprognostic (5.08e-2)" "unprognostic (1.10e-1)" "unprognostic (1.18e-2)" "unprognostic (1.65e-1)" "unprognostic (3.00e-2)" "unprognostic (5.88e-2)" "unprognostic (1.15e-1)" "unprognostic (1.78e-1)" "unprognostic (4.57e-2)" "unprognostic (5.32e-2)" "unprognostic (9.50e-2)" "unprognostic (2.49e-1)" "unprognostic (3.04e-3)" "unprognostic (1.37e-1)" "unprognostic (4.43e-3)" "unprognostic (2.49e-1)" "unprognostic (7.69e-2)" "unprognostic (4.31e-2)" RDH12 "FLJ30273, LCA13, RP53, SDR7C2" ENSG00000139988 "Retinol dehydrogenase 12" Q96NR8 14 67701886-67734451 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Sensory transduction, Vision" Oxidoreductase "Disease variant, Leber congenital amaurosis, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "retina: 206.6;skin 1: 61.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 149.0;Epididymal principal cells: 78.9;Esophageal apical cells: 128.0;Esophageal suprabasal cells: 99.5;Rod photoreceptor cells: 358.1;Suprabasal keratinocytes: 57.8" "Cell type enhanced" "Detected in many" "midbrain-derived inhibitory: 11.6;thalamic excitatory: 8.3" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 10.3;Skin Cutaneous Melanoma (TCGA): 9.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Kidney - Proximal tubular cells, Prostate - Prostate glandular cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 42: Retina - Visual perception" "Cluster 38: Sub-cortical - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 79: Photoreceptor cells - Phototransduction" 9 "unprognostic (1.60e-1)" "unprognostic (3.38e-2)" "unprognostic (1.73e-2)" "unprognostic (2.71e-1)" "potential prognostic favorable (7.94e-6)" "unprognostic (8.23e-2)" "unprognostic (2.04e-2)" "unprognostic (1.23e-1)" "unprognostic (6.28e-2)" "unprognostic (3.65e-1)" "unprognostic (5.34e-2)" "unprognostic (1.75e-1)" "unprognostic (5.54e-1)" "unprognostic (8.63e-3)" "unprognostic (1.41e-1)" "unprognostic (4.39e-1)" RDH13 SDR7C3 ENSG00000160439 "Retinol dehydrogenase 13" Q8NBN7 19 55039108-55071291 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 7 "Distal convoluted tubule cells: 43.7;Loop of henle epithelial cells: 35.3;Papillary tip epithelial cells: 46.9;Podocytes: 22.2;Proximal tubule cells: 16.2;Renal collecting duct intercalated cells: 41.9;Renal collecting duct principal cells: 27.8;Renal connecting tubule cells: 46.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042006 Approved Supported Mitochondria,Cytosol "Intracellular and membrane" Enzyme NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 58: Skin - Keratinization" "Cluster 1: Neurons - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 9 "Mitochondria, Cytosol" "HPA042006: " "unprognostic (1.50e-1)" "unprognostic (1.73e-2)" "unprognostic (3.75e-2)" "unprognostic (1.16e-1)" "unprognostic (5.92e-3)" "unprognostic (3.14e-1)" "unprognostic (1.34e-2)" "unprognostic (1.56e-3)" "unprognostic (9.18e-2)" "unprognostic (2.29e-2)" "unprognostic (1.76e-2)" "unprognostic (7.63e-2)" "potential prognostic favorable (7.16e-7)" "unprognostic (6.05e-2)" "unprognostic (6.01e-2)" "unprognostic (5.88e-2)" "unprognostic (6.96e-2)" "unprognostic (8.83e-2)" "unprognostic (4.61e-1)" "unprognostic (1.32e-1)" "unprognostic (7.79e-2)" "unprognostic (3.83e-1)" "unprognostic (2.06e-1)" "unprognostic (1.46e-1)" "unprognostic (6.69e-2)" "unprognostic (9.38e-2)" "unprognostic (1.94e-1)" "unprognostic (2.41e-2)" "unprognostic (3.56e-1)" "unprognostic (5.00e-3)" "unprognostic (7.37e-2)" RDH14 "PAN2, SDR7C4" ENSG00000240857 "Retinol dehydrogenase 14" Q9HBH5 2 18554723-18560679 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056686, HPA078577" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 21: Non-specific - Metabolism" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 108: Fibroblasts - ECM organization" 6 Nucleoplasm Cytosol "HPA056686: , HPA078577: " "unprognostic (8.42e-2)" "unprognostic (1.70e-1)" "unprognostic (1.44e-2)" "unprognostic (3.39e-1)" "unprognostic (3.04e-1)" "unprognostic (2.44e-1)" "unprognostic (4.06e-2)" "unprognostic (2.22e-1)" "unprognostic (7.57e-3)" "unprognostic (2.20e-2)" "potential prognostic favorable (1.16e-4)" "unprognostic (4.12e-2)" "unprognostic (1.53e-1)" "unprognostic (4.26e-3)" "unprognostic (3.40e-3)" "unprognostic (2.71e-2)" "unprognostic (7.66e-2)" "unprognostic (3.44e-2)" "unprognostic (1.06e-1)" "unprognostic (7.11e-2)" "unprognostic (1.54e-1)" "unprognostic (3.48e-1)" "unprognostic (3.40e-1)" "unprognostic (2.88e-1)" "unprognostic (1.50e-1)" "unprognostic (1.16e-1)" "unprognostic (2.90e-1)" "unprognostic (2.46e-1)" "unprognostic (7.84e-2)" "unprognostic (2.23e-1)" "unprognostic (2.54e-1)" RDH16 "RODH-4, SDR9C8" ENSG00000139547 "Retinol dehydrogenase 16" O75452 12 56951431-56959374 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 119 "liver: 812.5" "Cell type enriched" "Detected in some" 17 "Hepatocytes: 415.7" "Low cell type specificity" "Detected in some" "Cancer enriched" "Detected in many" 20 "Liver Hepatocellular Carcinoma (TCGA): 112.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.7" "Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA038518 Enhanced NA NA "Cluster 53: Liver - Plasma proteins" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 93: Hepatocytes - Bile production & excretion" "HPA038518: " "unprognostic (5.18e-2)" "unprognostic (3.30e-3)" "unprognostic (6.24e-2)" "unprognostic (9.77e-2)" "unprognostic (9.66e-3)" "unprognostic (6.64e-3)" "potential prognostic favorable (2.27e-5)" "unprognostic (8.44e-3)" "unprognostic (2.59e-1)" "unprognostic (2.91e-2)" "unprognostic (5.69e-2)" "unprognostic (3.23e-1)" RDH5 "HSD17B9, RDH1, SDR9C5" ENSG00000135437 "Retinol dehydrogenase 5" Q92781 12 55720367-55724705 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Sensory transduction, Steroid metabolism, Vision" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 88.7;liver: 55.1" "Cell type enhanced" "Detected in some" "Colonocytes: 8.0;Enteric stem cells: 3.4;Enteric transient amplifying cells: 4.3;Enterocytes: 18.3;Epididymal efferent duct absorptive cells: 7.7;Epididymal principal cells: 10.1;Gastric chief cells: 3.3;Neuroendocrine cells: 4.7;Paneth cells: 7.7;Retinal pigment epithelial cells: 17.1" "Cell type enhanced" "Detected in some" "ependymal cell: 1.5;pericyte: 1.4;vascular associated smooth muscle cell: 1.6" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 39.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063345 Uncertain Vesicles NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 15: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" 1 Vesicles "HPA063345: " "unprognostic (4.22e-2)" "unprognostic (8.47e-3)" "unprognostic (1.47e-3)" "unprognostic (2.10e-2)" "unprognostic (3.01e-1)" "unprognostic (1.25e-1)" "unprognostic (1.13e-1)" "unprognostic (1.47e-1)" "unprognostic (1.38e-1)" "unprognostic (3.53e-3)" "unprognostic (4.62e-1)" "unprognostic (3.96e-3)" "unprognostic (1.48e-2)" "unprognostic (7.85e-3)" "unprognostic (7.61e-3)" "unprognostic (1.63e-1)" "unprognostic (9.72e-2)" "unprognostic (1.41e-1)" "unprognostic (3.68e-1)" "unprognostic (1.22e-1)" "unprognostic (2.58e-1)" "unprognostic (8.61e-2)" "unprognostic (8.78e-2)" "unprognostic (1.04e-1)" "unprognostic (1.54e-1)" "unprognostic (1.20e-2)" "unprognostic (7.77e-2)" RDH8 "PRRDH, SDR28C2" ENSG00000080511 "Retinol dehydrogenase 8" Q9NYR8 19 10013249-10022279 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Sensory transduction, Vision" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 28 "retina: 106.2" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 47.6;Early spermatids: 61.3;Late primary spermatocytes: 43.1;Loop of henle epithelial cells: 51.9;Retinal bipolar cells: 25.2;Rod photoreceptor cells: 164.2" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "Skin Cutaneous Melanoma (TCGA): 6.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "skin cancer: 1.0" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA064473 Approved "Nucleoplasm,Midbody ring,Cytosol" Yes NA "Cluster 42: Retina - Visual perception" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 79: Photoreceptor cells - Phototransduction" Nucleoplasm "Midbody ring, Cytosol" "HPA064473: " "unprognostic (1.16e-2)" RDM1 "MGC33977, RAD52B" ENSG00000278023 "RAD52 motif containing 1" Q8NG50 17 35918066-35930773 "Essential proteins, Predicted intracellular proteins, Predicted membrane proteins" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 11.4" "Cell type enhanced" "Detected in some" "Early primary spermatocytes: 9.3;Early spermatids: 51.9;Late primary spermatocytes: 22.9;Late spermatids: 113.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory CD8 T-cell: 2.6" "Lineage enhanced" "Detected in single" "T-cells: 2.6" "Low cancer specificity" "Detected in many" "Adrenal gland - Mitotic cells (Adrenal gland), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "HPA024794, HPA067546" Enhanced Supported Nucleoli,Cytosol NA NA "Cluster 1: T-cells - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 4 Nucleoli Cytosol "HPA024794: , HPA067546: " "unprognostic (1.42e-2)" "unprognostic (3.55e-1)" "unprognostic (6.07e-2)" "unprognostic (1.72e-2)" "unprognostic (6.78e-2)" "unprognostic (6.17e-2)" "unprognostic (2.78e-3)" "potential prognostic unfavorable (7.07e-9)" "unprognostic (1.60e-2)" "unprognostic (1.60e-2)" "unprognostic (5.76e-2)" "unprognostic (1.72e-1)" "unprognostic (4.45e-2)" "unprognostic (4.10e-3)" "potential prognostic favorable (9.96e-6)" "unprognostic (8.86e-2)" "unprognostic (1.23e-1)" "unprognostic (1.17e-2)" RDX DFNB24 ENSG00000137710 Radixin P35241 11 109864295-110296712 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin capping, Actin-binding" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 146.4" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 1292.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Endothelial cells, Skin - Endothelial cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000263, HPA000763, CAB037312" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA 31000000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 24: Non-specific - Unknown function" "Cluster 18: Adrenal cortex cells - Steroidogensis" 26 "Plasma membrane" Nucleoplasm "CAB037312: , HPA000263: , HPA000763: " "unprognostic (1.97e-1)" "unprognostic (7.14e-3)" "unprognostic (2.22e-1)" "unprognostic (1.64e-2)" "unprognostic (2.71e-1)" "unprognostic (6.69e-2)" "unprognostic (2.88e-2)" "potential prognostic unfavorable (8.44e-4)" "unprognostic (2.65e-1)" "unprognostic (1.79e-2)" "potential prognostic favorable (2.99e-8)" "unprognostic (1.41e-2)" "unprognostic (5.91e-2)" "unprognostic (1.03e-1)" "unprognostic (1.24e-1)" "potential prognostic unfavorable (4.98e-5)" "unprognostic (2.00e-3)" "unprognostic (1.82e-1)" "unprognostic (2.98e-1)" "unprognostic (1.79e-1)" "unprognostic (7.76e-2)" "unprognostic (2.41e-3)" "potential prognostic unfavorable (4.36e-8)" "unprognostic (1.14e-1)" "unprognostic (2.12e-1)" "unprognostic (4.38e-2)" "unprognostic (2.76e-1)" "unprognostic (3.81e-2)" "unprognostic (3.99e-1)" "unprognostic (5.74e-2)" "unprognostic (2.21e-1)" REC114 "C15orf60, CT147, FLJ27520, FLJ36860, FLJ44083, LOC283677" ENSG00000183324 "REC114 meiotic recombination protein" Q7Z4M0 15 73443164-73560013 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, DNA recombination, Meiosis, Oogenesis, Spermatogenesis" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 37.5" "Group enriched" "Detected in many" 4 "Late primary spermatocytes: 347.9;Oocytes: 1335.5" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in single" 10 "Testicular Germ Cell Tumor (TCGA): 1.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Region enhanced" "Detected in many" "olfactory bulb: 6.1" "Low region specificity" "Detected in many" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 15: Non-specific - Transcription" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 41: Oocytes - Oogenesis" 1 "unprognostic (2.42e-1)" REC8 "kleisin-alpha, REC8L1, Rec8p" ENSG00000100918 "REC8 meiotic recombination protein" O95072 14 24171853-24180257 "Plasma proteins, Predicted intracellular proteins" "Chromosome partition, Meiosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.5;pituitary gland: 64.9" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 46.2;Early spermatids: 149.9;Fallopian tube ciliated cells: 43.3;Late primary spermatocytes: 83.3;Late spermatids: 83.6;Respiratory ciliated cells: 33.9" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 30.0;Uterine Corpus Endometrial Carcinoma (TCGA): 26.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Neuroblastoma: 23.4;testis cancer: 23.9" "Adipose visceral - Mesothelial cells, Colon - Enteric glia cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031727, HPA031729" Approved Approved Nucleoplasm NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 15 Nucleoplasm "HPA031727: , HPA031729: " "unprognostic (6.78e-3)" "unprognostic (5.38e-3)" "unprognostic (2.86e-1)" "unprognostic (1.55e-1)" "unprognostic (9.63e-2)" "unprognostic (3.44e-1)" "potential prognostic favorable (2.47e-6)" "potential prognostic favorable (7.60e-4)" "unprognostic (1.52e-1)" "unprognostic (4.39e-2)" "unprognostic (1.29e-1)" "unprognostic (1.52e-3)" "unprognostic (8.30e-2)" "unprognostic (2.51e-2)" "unprognostic (1.54e-1)" "unprognostic (2.10e-1)" "potential prognostic favorable (7.42e-5)" "potential prognostic favorable (2.45e-5)" "potential prognostic unfavorable (9.02e-4)" "unprognostic (2.79e-1)" "unprognostic (1.93e-2)" "unprognostic (8.02e-2)" "unprognostic (1.75e-1)" "unprognostic (2.75e-2)" "unprognostic (2.35e-1)" RECK "hRECK, ST15" ENSG00000122707 "Reversion inducing cysteine rich protein with kazal motifs" O95980 9 36036913-36124455 "Plasma proteins, Predicted membrane proteins" "Wnt signaling pathway" "Protease inhibitor, Serine protease inhibitor" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 123.0;Early primary spermatocytes: 137.5;Fibro-adipogenic progenitors: 155.4;Microglia: 153.0;Oligodendrocytes: 137.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Breast - Fibroblasts, Colon - Fibroblasts, Lung - Fibroblasts_1, Prostate - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025109, HPA071729" Supported Supported "Plasma membrane" NA NA 23000000 "Cluster 33: Non-specific - ATP binding" "Cluster 75: Ovary - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 2 "Plasma membrane" "CAB025109: , HPA071729: " "unprognostic (8.95e-2)" "unprognostic (5.11e-1)" "unprognostic (1.78e-1)" "unprognostic (1.56e-2)" "unprognostic (1.68e-1)" "unprognostic (1.37e-1)" "unprognostic (1.02e-1)" "unprognostic (2.02e-1)" "unprognostic (1.23e-1)" "unprognostic (8.56e-3)" "validated prognostic favorable (4.86e-6)" "validated prognostic favorable (2.02e-4)" "unprognostic (3.27e-2)" "unprognostic (3.61e-1)" "unprognostic (1.12e-2)" "unprognostic (1.88e-1)" "unprognostic (3.24e-1)" "unprognostic (1.52e-2)" "unprognostic (3.44e-1)" "unprognostic (3.05e-3)" "unprognostic (1.33e-1)" "unprognostic (1.34e-1)" "unprognostic (8.82e-2)" "unprognostic (2.27e-1)" "unprognostic (1.43e-1)" "unprognostic (2.95e-2)" "unprognostic (7.02e-3)" "unprognostic (4.35e-3)" "unprognostic (6.41e-2)" "unprognostic (4.88e-3)" "unprognostic (6.66e-3)" RECQL "RecQ1, RecQL1" ENSG00000004700 "RecQ like helicase" P46063 12 21468910-21501669 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA-binding, Helicase, Hydrolase, Isomerase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 118.4;Megakaryocytes: 148.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009743, HPA030960, HPA030961, HPA064259, CAB080253" Enhanced Supported Nucleoplasm NA NA 24000 "Cluster 33: Non-specific - ATP binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 21 Nucleoplasm "CAB009743: , CAB080253: , HPA030960: , HPA030961: , HPA064259: " "unprognostic (1.68e-1)" "unprognostic (2.32e-2)" "unprognostic (1.27e-1)" "unprognostic (8.38e-2)" "unprognostic (3.63e-2)" "unprognostic (1.75e-1)" "unprognostic (2.81e-1)" "unprognostic (4.74e-2)" "unprognostic (3.77e-1)" "unprognostic (9.65e-3)" "unprognostic (1.30e-3)" "unprognostic (3.22e-1)" "unprognostic (1.59e-1)" "unprognostic (2.51e-3)" "unprognostic (1.05e-2)" "unprognostic (1.07e-3)" "potential prognostic unfavorable (2.14e-4)" "unprognostic (7.63e-2)" "unprognostic (2.02e-2)" "unprognostic (4.86e-3)" "unprognostic (1.08e-3)" "unprognostic (2.44e-2)" "unprognostic (3.95e-3)" "unprognostic (6.45e-2)" "unprognostic (1.40e-1)" "unprognostic (3.89e-2)" "unprognostic (9.80e-2)" "unprognostic (7.29e-2)" "unprognostic (5.81e-2)" "unprognostic (2.58e-1)" "unprognostic (2.95e-1)" RECQL4 RecQ4 ENSG00000160957 "RecQ like helicase 4" O94761 8 144511288-144517845 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA-binding, Helicase, Hydrolase, Isomerase" "Cancer-related genes, Cataract, Craniosynostosis, Disease variant, Dwarfism, Ectodermal dysplasia, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 23.6;testis: 22.1" "Cell type enhanced" "Detected in many" "Breast lactating cells: 18.4;Differentiating spermatogonia: 22.0;Early primary spermatocytes: 32.4;Erythrocyte progenitors: 19.6;Megakaryocyte progenitors: 12.2;Monocyte progenitors: 13.9;Oocytes: 32.2;Undifferentiated spermatogonia: 11.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" "CAB017800, HPA025821" Supported Enhanced Nucleoplasm NA Yes "Cluster 23: B-cells - Immunoglobulins" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 37: Neurons - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 122 Nucleoplasm "CAB017800: , HPA025821: " "unprognostic (4.41e-1)" "unprognostic (8.06e-2)" "unprognostic (1.34e-1)" "unprognostic (1.36e-2)" "unprognostic (2.33e-1)" "unprognostic (3.24e-1)" "unprognostic (8.17e-2)" "unprognostic (2.33e-2)" "unprognostic (2.81e-2)" "unprognostic (2.52e-2)" "validated prognostic unfavorable (2.52e-7)" "validated prognostic unfavorable (2.80e-4)" "unprognostic (9.41e-3)" "validated prognostic unfavorable (3.86e-4)" "validated prognostic unfavorable (3.81e-6)" "potential prognostic unfavorable (1.76e-5)" "unprognostic (1.02e-2)" "unprognostic (1.11e-1)" "unprognostic (1.29e-1)" "unprognostic (8.81e-2)" "potential prognostic favorable (7.75e-4)" "unprognostic (4.67e-2)" "unprognostic (1.13e-3)" "unprognostic (1.99e-2)" "unprognostic (2.84e-1)" "unprognostic (1.36e-1)" "unprognostic (1.25e-2)" "unprognostic (1.32e-2)" "unprognostic (2.28e-1)" "unprognostic (3.87e-3)" "unprognostic (1.43e-1)" RECQL5 "FLJ90603, RecQ5" ENSG00000108469 "RecQ like helicase 5" O94762 17 75626845-75667189 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, DNA replication" "DNA-binding, Helicase, Hydrolase, Isomerase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 75.5;Esophageal apical cells: 118.2;Foveolar cells: 88.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029971 Supported Nucleoplasm,Cytosol NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 5: Spleen - Immune response" "Cluster 11: White matter - Signal transduction" "Cluster 27: Breast cancer - Unknown function" "Cluster 68: Foveolar cells - Mucosal defense" 36 Nucleoplasm Cytosol "HPA029971: " "unprognostic (4.79e-3)" "unprognostic (1.50e-1)" "unprognostic (3.27e-2)" "unprognostic (3.45e-2)" "unprognostic (3.28e-1)" "unprognostic (7.57e-2)" "unprognostic (1.15e-1)" "unprognostic (4.60e-3)" "unprognostic (1.38e-1)" "unprognostic (2.50e-2)" "unprognostic (1.41e-1)" "unprognostic (7.31e-2)" "unprognostic (8.23e-2)" "potential prognostic unfavorable (1.24e-4)" "unprognostic (1.56e-1)" "unprognostic (1.06e-1)" "unprognostic (3.36e-2)" "unprognostic (1.12e-1)" "unprognostic (2.65e-3)" "unprognostic (1.43e-1)" "unprognostic (6.59e-3)" "unprognostic (2.59e-3)" "potential prognostic unfavorable (2.11e-4)" "unprognostic (2.76e-2)" "unprognostic (1.00e-3)" "potential prognostic favorable (1.53e-5)" "unprognostic (2.68e-1)" "unprognostic (1.74e-1)" "unprognostic (3.05e-1)" "unprognostic (3.20e-1)" "unprognostic (8.20e-2)" REELD1 ENSG00000250673 "Reeler domain containing 1" A0A1B0GV85 4 146214515-146232267 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Adipocytes: 1.9;Bergmann glia: 5.0;Myonuclei: 1.8;Prostatic glandular cells: 1.9;Proximal tubule cells: 1.9;Renal connecting tubule cells: 1.5;Respiratory deuterosomal cells: 3.1;Thymocytes: 1.7" "Cell type enhanced" "Detected in some" "Bergmann glia: 6.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA "Cluster 5: Spleen - Immune response" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" "unprognostic (9.55e-2)" REEP1 "C2orf23, FLJ13110, SPG31, Yip2a" ENSG00000068615 "Receptor accessory protein 1" Q9H902 2 86213993-86338083 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 42.3" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 137.4;Lactotrophs: 178.0;Myonuclei: 202.1;Other brain neurons: 157.8;Retinal amacrine cells: 108.8;Retinal ganglion cells: 123.6;Sertoli cells: 739.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 15.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Kidney - Proximal tubular cells, Pituitary gland - Lactotropes, Prostate - Smooth muscle cells, Skin - Smooth muscle cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058061 Enhanced NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 1: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 19 "HPA058061: " "unprognostic (1.46e-2)" "unprognostic (6.50e-3)" "unprognostic (7.07e-2)" "unprognostic (1.85e-3)" "unprognostic (1.46e-1)" "unprognostic (2.27e-1)" "unprognostic (2.13e-2)" "unprognostic (3.54e-3)" "unprognostic (5.85e-2)" "unprognostic (2.34e-2)" "validated prognostic favorable (4.43e-5)" "validated prognostic favorable (1.55e-5)" "unprognostic (7.13e-2)" "unprognostic (1.44e-1)" "unprognostic (4.98e-2)" "unprognostic (2.95e-1)" "unprognostic (3.39e-2)" "unprognostic (3.65e-2)" "unprognostic (3.01e-2)" "unprognostic (1.03e-1)" "unprognostic (1.24e-1)" "unprognostic (9.24e-2)" "unprognostic (1.24e-1)" "unprognostic (8.75e-3)" "unprognostic (4.04e-3)" "unprognostic (9.69e-2)" "unprognostic (2.41e-1)" "unprognostic (6.57e-2)" REEP2 "C5orf19, SGC32445, SPG72, Yip2d" ENSG00000132563 "Receptor accessory protein 2" Q9BRK0 5 138439057-138446969 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 141.9;choroid plexus: 97.9" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 76.1;Brain inhibitory neurons: 65.5;Cone photoreceptor cells: 97.3;Ependymal cells: 36.9;Gonadotrophs: 35.7;Oligodendrocyte progenitor cells: 37.0;Oocytes: 32.2;Other brain neurons: 85.5;Retinal amacrine cells: 45.1;Retinal bipolar cells: 30.1;Retinal ganglion cells: 46.4;Rod photoreceptor cells: 61.3" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 9 "Glioblastoma Multiforme (TCGA): 76.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 37.1" "Adrenal gland - Adrenal medulla cells, Pancreas - Alpha cells, Pancreas - Beta cells, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031813, HPA076571" Enhanced Supported Approved "Endoplasmic reticulum" NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" 33 "Endoplasmic reticulum" "HPA031813: , HPA076571: " "unprognostic (3.65e-3)" "potential prognostic favorable (1.40e-4)" "unprognostic (4.25e-1)" "unprognostic (2.23e-2)" "unprognostic (2.60e-3)" "unprognostic (7.44e-2)" "unprognostic (6.78e-2)" "unprognostic (1.98e-1)" "unprognostic (5.87e-2)" "unprognostic (2.67e-2)" "unprognostic (3.13e-1)" "unprognostic (9.29e-2)" "unprognostic (3.91e-1)" "unprognostic (6.60e-3)" "unprognostic (2.70e-1)" "unprognostic (2.71e-2)" "unprognostic (1.12e-2)" "unprognostic (5.23e-2)" "unprognostic (2.39e-3)" "unprognostic (3.11e-1)" "unprognostic (7.98e-2)" "potential prognostic unfavorable (7.43e-4)" "unprognostic (3.25e-2)" "potential prognostic favorable (8.60e-4)" "unprognostic (3.49e-2)" "potential prognostic favorable (4.78e-4)" "unprognostic (6.81e-3)" "unprognostic (7.92e-2)" REEP3 "C10orf74, Yip2b" ENSG00000165476 "Receptor accessory protein 3" Q6NUK4 10 63521401-63625128 "Predicted membrane proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 471.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skeletal muscle - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 17: Intestine - Digestion" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 21 "unprognostic (8.35e-3)" "unprognostic (3.54e-2)" "unprognostic (3.37e-1)" "unprognostic (2.42e-3)" "unprognostic (7.03e-2)" "potential prognostic unfavorable (2.53e-4)" "unprognostic (1.77e-2)" "unprognostic (2.09e-1)" "unprognostic (1.47e-3)" "unprognostic (1.05e-1)" "potential prognostic favorable (7.51e-6)" "unprognostic (4.20e-2)" "unprognostic (1.60e-1)" "unprognostic (2.14e-3)" "unprognostic (1.48e-2)" "unprognostic (3.04e-3)" "unprognostic (7.86e-2)" "unprognostic (1.20e-2)" "unprognostic (1.47e-2)" "unprognostic (1.24e-1)" "unprognostic (2.11e-3)" "unprognostic (1.13e-3)" "unprognostic (3.98e-2)" "unprognostic (1.74e-1)" "unprognostic (6.67e-2)" "unprognostic (7.55e-2)" "unprognostic (1.46e-1)" "unprognostic (1.16e-1)" "unprognostic (8.86e-2)" "unprognostic (1.03e-1)" "unprognostic (2.02e-1)" REEP4 "C8orf20, FLJ22246, FLJ22277, PP432, Yip2c" ENSG00000168476 "Receptor accessory protein 4" Q9H6H4 8 22138020-22141951 "Predicted membrane proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 90.4;skin 1: 91.6" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 351.0;Esophageal basal cells: 87.6;Esophageal suprabasal cells: 160.3;Late primary spermatocytes: 116.2;Migrating cytotrophoblasts: 66.4;Syncytiotrophoblasts: 118.2" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 29.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042683 Approved Supported "Endoplasmic reticulum" No Yes "Cluster 10: Non-specific - Membrane trafficking" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 40: Non-specific - Unknown function" "Cluster 85: Squamous epithelial cells - Keratinization" 145 "Endoplasmic reticulum" "HPA042683: " "unprognostic (4.15e-1)" "unprognostic (1.48e-1)" "unprognostic (9.18e-3)" "unprognostic (1.97e-1)" "unprognostic (2.79e-2)" "unprognostic (1.25e-1)" "unprognostic (2.32e-1)" "unprognostic (6.81e-2)" "unprognostic (2.18e-1)" "unprognostic (1.23e-2)" "potential prognostic unfavorable (1.28e-5)" "unprognostic (2.22e-3)" "unprognostic (8.22e-3)" "potential prognostic unfavorable (1.61e-6)" "unprognostic (1.88e-2)" "unprognostic (3.50e-2)" "unprognostic (6.27e-2)" "unprognostic (2.47e-2)" "unprognostic (1.58e-1)" "unprognostic (2.97e-1)" "unprognostic (5.26e-2)" "unprognostic (9.86e-2)" "unprognostic (8.57e-3)" "unprognostic (2.40e-1)" "unprognostic (1.57e-1)" "unprognostic (1.01e-1)" "unprognostic (1.53e-1)" "unprognostic (1.22e-1)" "unprognostic (2.55e-1)" "unprognostic (2.42e-3)" "unprognostic (5.25e-2)" REEP5 "C5orf18, D5S346, DP1, POB16, TB2, Yip2e" ENSG00000129625 "Receptor accessory protein 5" Q00765 5 112876385-112922289 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 613.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003895, HPA069960" Approved Supported "Endoplasmic reticulum" NA NA 6600 "Cluster 40: Monocytes - Innate immune response" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 8: Non-specific - Secretory pathway" 106 "Endoplasmic reticulum" "HPA003895: , HPA069960: " "unprognostic (2.61e-2)" "potential prognostic unfavorable (4.74e-4)" "unprognostic (7.36e-2)" "unprognostic (9.14e-2)" "unprognostic (2.50e-1)" "unprognostic (1.47e-1)" "unprognostic (2.30e-1)" "unprognostic (8.92e-3)" "unprognostic (3.34e-2)" "unprognostic (1.40e-1)" "validated prognostic favorable (2.30e-8)" "validated prognostic favorable (2.07e-5)" "unprognostic (1.20e-1)" "unprognostic (1.00e-1)" "unprognostic (6.57e-3)" "unprognostic (8.94e-2)" "unprognostic (3.24e-1)" "unprognostic (1.11e-2)" "potential prognostic unfavorable (1.36e-5)" "unprognostic (6.29e-2)" "unprognostic (9.93e-3)" "unprognostic (9.63e-2)" "unprognostic (2.46e-2)" "unprognostic (3.65e-1)" "unprognostic (2.50e-1)" "unprognostic (4.52e-2)" "unprognostic (1.02e-1)" "unprognostic (1.26e-1)" "unprognostic (1.52e-1)" "unprognostic (2.12e-1)" "unprognostic (2.35e-2)" REEP6 "C19orf32, DP1L1, FLJ25383, Yip2f" ENSG00000115255 "Receptor accessory protein 6" Q96HR9 19 1491166-1497927 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 204.5;liver: 523.4;testis: 363.6" "Cell type enriched" "Detected in many" 7 "Late spermatids: 5757.5" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 267.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Breast glandular cells, Breast - Breast glandular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells, Testis - Late spermatids" "HPA003895, HPA048015" Enhanced Supported "Endoplasmic reticulum,Acrosome" NA NA 6800 "Cluster 33: Non-specific - ATP binding" "Cluster 47: Testis - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 49 "Endoplasmic reticulum" Acrosome "HPA003895: , HPA048015: " "unprognostic (1.33e-2)" "unprognostic (1.86e-1)" "unprognostic (1.12e-2)" "unprognostic (1.63e-1)" "unprognostic (7.74e-2)" "unprognostic (4.94e-2)" "unprognostic (1.92e-1)" "unprognostic (9.23e-2)" "unprognostic (4.26e-2)" "unprognostic (2.49e-2)" "potential prognostic unfavorable (2.97e-4)" "unprognostic (1.59e-2)" "unprognostic (1.30e-1)" "unprognostic (1.44e-1)" "unprognostic (7.71e-2)" "unprognostic (4.20e-3)" "unprognostic (3.30e-2)" "unprognostic (6.73e-2)" "unprognostic (6.08e-1)" "unprognostic (2.97e-1)" "potential prognostic unfavorable (5.39e-4)" "unprognostic (4.40e-2)" "unprognostic (1.51e-2)" "unprognostic (2.35e-1)" "unprognostic (7.48e-2)" "unprognostic (2.50e-1)" "unprognostic (2.72e-2)" "unprognostic (2.58e-1)" "unprognostic (1.15e-1)" "unprognostic (7.28e-2)" "unprognostic (5.24e-2)" REG1A "PSP, PSPS, PSPS1, PTP, REG" ENSG00000115386 "Regenerating family member 1 alpha" P05451 2 79120362-79123409 "Plasma proteins, Predicted secreted proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 15 "pancreas: 108891.6" "Cell type enriched" "Detected in some" 11 "Pancreatic acinar cells: 145430.3" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Colon Adenocarcinoma (TCGA): 1349.6;Pancreatic Adenocarcinoma (TCGA): 4301.5;Stomach Adenocarcinoma (TCGA): 1894.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 47 "breast cancer: 94.7;colorectal cancer: 64.6;Gastric cancer: 52.0;Rhabdoid: 138.8" "Pancreas - Ductal cells" "Low region specificity" "Detected in single" "CAB025138, HPA045549, HPA045579" Enhanced "Secreted to digestive system" "No annotated function" NA NA 37000000 "Cluster 8: Pancreas - Proteolysis" "Cluster 27: Breast cancer - Unknown function" "Cluster 5: Pancreatic acinar cells - Pancreatic exocrine secretion" 2 "CAB025138: , HPA045549: , HPA045579: " "unprognostic (6.44e-1)" "unprognostic (3.13e-1)" "unprognostic (1.80e-1)" "unprognostic (2.65e-1)" "potential prognostic favorable (8.41e-4)" "unprognostic (9.11e-2)" "unprognostic (1.22e-1)" "unprognostic (2.44e-1)" "unprognostic (3.87e-1)" "unprognostic (1.75e-1)" "unprognostic (1.85e-1)" "unprognostic (5.28e-2)" "unprognostic (8.57e-2)" "unprognostic (2.65e-1)" "unprognostic (3.57e-1)" "unprognostic (7.21e-2)" "unprognostic (4.71e-2)" "unprognostic (8.65e-2)" "unprognostic (2.56e-2)" REG1B "PSPS2, REGH, REGI-BETA, REGL" ENSG00000172023 "Regenerating family member 1 beta" P48304 2 79085023-79088019 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 15 "pancreas: 40073.0" "Cell type enriched" "Detected in some" 10 "Pancreatic acinar cells: 32647.3" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Colon Adenocarcinoma (TCGA): 322.7;Pancreatic Adenocarcinoma (TCGA): 963.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "colorectal cancer: 1.3" "Pancreas - Ductal cells" "HPA045549, HPA045579" Supported "Secreted to digestive system" "No annotated function" NA NA 32000000 "Cluster 8: Pancreas - Proteolysis" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Pancreatic acinar cells - Pancreatic exocrine secretion" 4 "HPA045549: , HPA045579: " "unprognostic (2.59e-1)" "unprognostic (1.58e-2)" "unprognostic (8.11e-2)" "unprognostic (7.55e-2)" "unprognostic (6.05e-2)" "unprognostic (5.15e-1)" "unprognostic (9.88e-2)" "potential prognostic unfavorable (5.49e-4)" "unprognostic (8.03e-2)" "unprognostic (1.06e-2)" "unprognostic (2.04e-1)" REG3A "HIP, PAP, PAP1, PBCGF, REG-III, REG3" ENSG00000172016 "Regenerating family member 3 alpha" Q06141 2 79157003-79159753 "Plasma proteins, Predicted secreted proteins, Transporters" "Acute phase, Inflammatory response" Antimicrobial "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 62 "intestine: 6346.3;pancreas: 11381.6" "Group enriched" "Detected in some" 20 "Pancreatic acinar cells: 30200.1;Paneth cells: 26495.6" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 874.1;Pancreatic Adenocarcinoma (TCGA): 2145.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 17 "colorectal cancer: 13.6" "Pancreas - Ductal cells" "HPA047894, HPA048334, HPA060705" Supported Approved Cytosol "Secreted to digestive system" "Acute phase" NA NA 7100000 "Cluster 60: Stomach - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Pancreatic acinar cells - Pancreatic exocrine secretion" 5 Cytosol "HPA047894: , HPA048334: , HPA060705: " "unprognostic (2.28e-1)" "unprognostic (2.56e-1)" "unprognostic (4.52e-2)" "unprognostic (3.48e-1)" "unprognostic (6.82e-2)" "unprognostic (3.62e-2)" "unprognostic (7.13e-2)" "unprognostic (2.22e-1)" "unprognostic (1.00e-2)" "unprognostic (6.20e-2)" REG3G "LPPM429, PAP1B, UNQ429" ENSG00000143954 "Regenerating family member 3 gamma" Q6UW15 2 79025686-79028505 "Predicted secreted proteins" "Acute phase, Inflammatory response" Antimicrobial "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 22 "pancreas: 3450.0" "Cell type enriched" "Detected in some" 68 "Pancreatic acinar cells: 7000.5" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 13 "Pancreatic Adenocarcinoma (TCGA): 221.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Pancreas - Ductal cells" "HPA047894, HPA048334, HPA060705" Uncertain Approved Cytosol "Secreted to digestive system" "Acute phase" NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 69: Skin cancer - ECM organization" "Cluster 5: Pancreatic acinar cells - Pancreatic exocrine secretion" 1 Cytosol "HPA047894: , HPA048334: , HPA060705: " "unprognostic (3.86e-2)" "unprognostic (2.11e-1)" "unprognostic (2.16e-1)" "unprognostic (1.12e-1)" "unprognostic (1.40e-3)" "unprognostic (4.89e-1)" "unprognostic (5.07e-2)" "unprognostic (1.85e-1)" REG4 "GISP, REG-IV, RELP" ENSG00000134193 "Regenerating family member 4" Q9BYZ8 1 119794017-119811580 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 623.9" "Group enriched" "Detected in some" 8 "Goblet cells: 4100.5;Neuroendocrine cells: 5724.4" "Not detected" "Not detected" "Group enriched" "Detected in many" 10 "Colon Adenocarcinoma (TCGA): 748.7;Pancreatic Adenocarcinoma (TCGA): 920.3;Rectum Adenocarcinoma (TCGA): 425.5;Stomach Adenocarcinoma (TCGA): 674.4" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 6 "naive CD8 T-cell: 24.7" "Lineage enriched" "Detected in single" 100 "T-cells: 24.7" "Group enriched" "Detected in many" 4 "colorectal cancer: 119.0;Esophageal cancer: 120.2;Gastric cancer: 177.8;pancreatic cancer: 62.6" "Colon - Colon enterocytes, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "CAB025867, HPA046555" Enhanced "Secreted to digestive system" "No annotated function" NA NA 190000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 77: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" 1 "CAB025867: , HPA046555: " "unprognostic (9.48e-3)" "unprognostic (1.80e-1)" "unprognostic (9.70e-3)" "unprognostic (1.49e-1)" "unprognostic (2.09e-3)" "potential prognostic unfavorable (7.11e-5)" "unprognostic (9.20e-2)" "unprognostic (1.33e-1)" "unprognostic (8.13e-2)" "unprognostic (1.45e-1)" "unprognostic (3.64e-1)" "unprognostic (6.42e-3)" "unprognostic (6.68e-2)" "unprognostic (5.05e-2)" "unprognostic (1.02e-1)" REL "c-Rel, HIVEN86A, I-Rel" ENSG00000162924 "REL proto-oncogene, NF-kB subunit" Q04864 2 60881491-60931612 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, RAS pathway related proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 35.3" "Cell type enhanced" "Detected in many" "B-cells: 620.1;cDC: 989.3;Innate lymphoid cells: 620.5;Macrophages: 541.4;Mast cells: 802.4;monocytes: 783.3;Neutrophils: 1082.3;NK-cells: 631.2;Urothelial cells: 569.2" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 241.5;leukocyte: 197.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "lymphoma: 34.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" CAB004404 Uncertain NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 55: Lymphoma - Immune response" "Cluster 103: Non-specific - Basic cellular processes" 191 "CAB004404: " "unprognostic (1.15e-1)" "unprognostic (2.72e-1)" "unprognostic (2.94e-1)" "unprognostic (1.40e-2)" "unprognostic (4.21e-1)" "unprognostic (9.71e-3)" "unprognostic (3.52e-1)" "unprognostic (1.02e-1)" "unprognostic (1.17e-1)" "potential prognostic unfavorable (2.11e-4)" "unprognostic (1.85e-2)" "unprognostic (7.51e-2)" "unprognostic (1.90e-1)" "unprognostic (9.94e-2)" "unprognostic (4.74e-2)" "unprognostic (2.20e-1)" "unprognostic (6.03e-3)" "unprognostic (1.28e-1)" "unprognostic (6.57e-2)" "unprognostic (2.04e-1)" "potential prognostic unfavorable (3.73e-4)" "unprognostic (4.91e-2)" "unprognostic (1.83e-3)" "unprognostic (8.45e-2)" "unprognostic (1.08e-2)" "potential prognostic favorable (6.61e-5)" "unprognostic (3.12e-1)" "unprognostic (1.21e-1)" "unprognostic (3.10e-1)" "unprognostic (1.60e-1)" "unprognostic (2.17e-1)" RELA "NFKB3, p65" ENSG00000173039 "RELA proto-oncogene, NF-kB subunit" Q04206 11 65653599-65663090 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins, RAS pathway related proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 155.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004264, CAB005030, HPA063461" Supported Enhanced Cytosol NA NA "Cluster 1: T-cells - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 6: Non-specific - Immune response" "Cluster 24: Non-specific - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 281 Cytosol "CAB004264: , CAB005030: , HPA063461: " "unprognostic (1.83e-1)" "unprognostic (3.70e-1)" "unprognostic (1.42e-1)" "unprognostic (2.16e-2)" "unprognostic (2.00e-1)" "unprognostic (3.25e-2)" "unprognostic (2.28e-1)" "unprognostic (1.19e-1)" "unprognostic (2.83e-1)" "unprognostic (2.52e-2)" "unprognostic (6.99e-3)" "unprognostic (2.25e-1)" "unprognostic (2.74e-1)" "potential prognostic unfavorable (9.99e-4)" "unprognostic (1.07e-1)" "unprognostic (3.28e-3)" "potential prognostic unfavorable (5.27e-6)" "unprognostic (1.68e-2)" "unprognostic (9.47e-2)" "unprognostic (1.14e-2)" "unprognostic (8.82e-2)" "unprognostic (2.37e-2)" "unprognostic (3.44e-3)" "unprognostic (8.77e-2)" "unprognostic (1.67e-1)" "unprognostic (2.88e-1)" "unprognostic (1.68e-1)" "unprognostic (3.64e-1)" "unprognostic (1.71e-1)" "unprognostic (1.38e-1)" "unprognostic (9.10e-3)" RELB REL-B ENSG00000104856 "RELB proto-oncogene, NF-kB subunit" Q01201 19 45001461-45038192 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Enterocytes: 323.2;Mast cells: 295.0;Neutrophils: 625.2" "Cell type enhanced" "Detected in many" "endothelial cell: 24.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 15.6" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 81.1" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007753, HPA040506" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 55: Lymphoma - Immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 47 Nucleoplasm Cytosol "CAB007753: , HPA040506: " "unprognostic (1.01e-1)" "unprognostic (2.23e-3)" "unprognostic (9.68e-2)" "unprognostic (2.05e-1)" "unprognostic (2.56e-1)" "unprognostic (4.35e-2)" "unprognostic (3.87e-2)" "unprognostic (2.12e-2)" "unprognostic (1.48e-2)" "unprognostic (1.77e-1)" "unprognostic (1.00e-2)" "unprognostic (2.61e-1)" "unprognostic (2.09e-1)" "unprognostic (3.81e-3)" "unprognostic (9.54e-2)" "unprognostic (9.54e-3)" "unprognostic (3.65e-2)" "unprognostic (7.64e-2)" "unprognostic (2.33e-1)" "unprognostic (3.60e-3)" "unprognostic (1.03e-1)" "unprognostic (1.39e-1)" "unprognostic (4.04e-2)" "unprognostic (7.02e-2)" "unprognostic (1.05e-1)" "unprognostic (3.29e-3)" "unprognostic (1.06e-1)" "unprognostic (7.95e-2)" "unprognostic (5.60e-2)" "unprognostic (1.52e-1)" "unprognostic (2.75e-1)" RELCH "FLJ33841, HsT3308, HsT885, KIAA1468" ENSG00000134444 "RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing" Q9P260 18 62187255-62310249 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 454.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039708, HPA040038" Approved NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 31: Non-specific - Transcription" "Cluster 13: Non-specific - Mixed function" "Cluster 7: Non-specific - Transcription" 11 "HPA039708: , HPA040038: " "unprognostic (1.29e-1)" "unprognostic (5.40e-2)" "unprognostic (1.02e-1)" "unprognostic (1.16e-3)" "unprognostic (6.54e-2)" "unprognostic (2.04e-1)" "potential prognostic favorable (4.29e-4)" "unprognostic (4.82e-2)" "unprognostic (5.07e-2)" "unprognostic (1.06e-3)" "unprognostic (4.49e-3)" "unprognostic (9.42e-3)" "unprognostic (1.51e-3)" "unprognostic (2.32e-1)" "unprognostic (5.03e-2)" "unprognostic (6.41e-2)" "unprognostic (5.84e-2)" "unprognostic (5.72e-2)" "unprognostic (7.40e-2)" "unprognostic (3.60e-1)" "unprognostic (2.48e-2)" "unprognostic (4.55e-1)" "unprognostic (1.30e-2)" "unprognostic (8.30e-2)" "unprognostic (7.53e-2)" "unprognostic (2.41e-2)" "unprognostic (4.71e-2)" "unprognostic (1.09e-1)" "unprognostic (4.54e-2)" RELL1 ENSG00000181826 "RELT like 1" Q8IUW5 4 37590800-37686376 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 33.6" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 477.4;Neutrophils: 525.7;Parietal cells: 449.0;pDCs: 218.1" "Cell type enhanced" "Detected in many" "endothelial cell: 159.3;pericyte: 180.9;vascular associated smooth muscle cell: 155.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 58.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Kidney - Endothelial cells, Minor Salivary Gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013377 Approved Supported "Plasma membrane,Microtubules" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 32: Non-specific - Cell proliferation" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 5 "Plasma membrane, Microtubules" "HPA013377: " "unprognostic (2.17e-1)" "unprognostic (1.41e-1)" "unprognostic (1.42e-2)" "unprognostic (3.21e-2)" "unprognostic (2.31e-1)" "unprognostic (5.92e-3)" "unprognostic (3.03e-1)" "unprognostic (6.85e-2)" "unprognostic (6.07e-2)" "unprognostic (1.37e-2)" "unprognostic (1.21e-1)" "potential prognostic favorable (6.82e-6)" "unprognostic (2.73e-3)" "unprognostic (2.86e-2)" "unprognostic (5.74e-2)" "unprognostic (7.94e-3)" "unprognostic (2.66e-1)" "unprognostic (1.28e-1)" "unprognostic (1.25e-2)" "unprognostic (7.04e-2)" "unprognostic (2.99e-1)" "unprognostic (2.20e-1)" "unprognostic (1.28e-1)" "unprognostic (2.71e-1)" "unprognostic (5.94e-3)" "unprognostic (3.17e-2)" "unprognostic (1.45e-1)" "unprognostic (1.18e-1)" "unprognostic (2.74e-1)" "unprognostic (1.07e-1)" "unprognostic (3.89e-2)" RELL2 "C5orf16, FLJ90583" ENSG00000164620 "RELT like 2" Q8NC24 5 141636950-141641064 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.0;parathyroid gland: 15.2;pituitary gland: 15.6" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 23.0;Brain inhibitory neurons: 26.0;Early primary spermatocytes: 18.1;Other brain neurons: 27.6;Retinal amacrine cells: 25.5;Retinal horizontal cells: 32.1;Tuft cells: 34.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Pituitary gland - Somatotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077928 Uncertain Vesicles NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 109: Neurons - Neuronal signaling" 28 Vesicles "HPA077928: " "unprognostic (6.85e-2)" "unprognostic (8.03e-2)" "unprognostic (5.29e-2)" "unprognostic (9.37e-2)" "unprognostic (1.66e-1)" "unprognostic (1.01e-1)" "potential prognostic unfavorable (8.74e-4)" "unprognostic (8.55e-2)" "unprognostic (1.39e-1)" "unprognostic (1.70e-1)" "unprognostic (5.74e-3)" "potential prognostic favorable (7.72e-5)" "unprognostic (2.41e-2)" "unprognostic (2.68e-1)" "unprognostic (2.95e-1)" "unprognostic (1.12e-1)" "unprognostic (1.98e-2)" "unprognostic (6.15e-2)" "unprognostic (3.99e-3)" "unprognostic (1.69e-3)" "unprognostic (2.30e-2)" "unprognostic (2.93e-2)" "unprognostic (1.23e-1)" "unprognostic (9.65e-2)" "unprognostic (6.45e-2)" "unprognostic (1.57e-1)" "unprognostic (3.97e-2)" "unprognostic (6.24e-2)" "unprognostic (1.42e-2)" RELN "PRO1598, RL" ENSG00000189056 Reelin P78509 7 103471381-103989658 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Developmental protein, Hydrolase, Protease, Serine protease" "Disease variant, Epilepsy, Lissencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 26.2;liver: 12.6" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 170.2;Brain excitatory neurons: 435.9;Brain inhibitory neurons: 342.6;Lymphatic endothelial cells: 632.5;Other brain neurons: 108.1;Retinal amacrine cells: 97.4;Retinal bipolar cells: 130.2;Retinal ganglion cells: 220.2;Schwann cells: 204.3" "Cell type enhanced" "Detected in all" "CGE interneuron: 1703.7;upper rhombic lip: 1671.0" "Cancer enhanced" "Detected in some" "Kidney Renal Papillary Cell Carcinoma (TCGA): 3.8" "Region enriched" "Detected in all" 8 "cerebellum: 141.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 21.7;liver cancer: 12.5;Myeloma: 11.2" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal medulla cells, Pancreas - Fibroblasts, Testis - Late spermatids" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 148.3" HPA077891 Approved "Golgi apparatus,Vesicles" "Secreted in brain" "Developmental protein" NA NA 45000000 "Cluster 27: Cerebellum - Synaptic function" "Cluster 35: Non-specific - DNA binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 3 "Golgi apparatus" Vesicles "HPA077891: " "unprognostic (1.16e-1)" "unprognostic (3.19e-2)" "unprognostic (1.38e-2)" "unprognostic (1.26e-1)" "unprognostic (1.76e-1)" "unprognostic (3.47e-2)" "unprognostic (8.86e-2)" RELT "FLJ14993, TNFRSF19L" ENSG00000054967 "RELT TNF receptor" Q969Z4 11 73376399-73397474 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis Receptor "Amelogenesis imperfecta, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "bone marrow: 146.0" "Cell type enhanced" "Detected in many" "cDC: 69.2;Hofbauer cells: 43.0;Macrophages: 47.1;Monocyte progenitors: 45.5;monocytes: 86.2;Neutrophils: 144.9;pDCs: 88.5" "Cell type enhanced" "Detected in many" "leukocyte: 23.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042269 Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 15: Bone marrow - Innate immune response" "Cluster 11: White matter - Signal transduction" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 17 Cytosol "Nucleoplasm, Nucleoli" "HPA042269: " "unprognostic (7.86e-2)" "unprognostic (3.19e-1)" "unprognostic (2.36e-1)" "unprognostic (1.93e-2)" "unprognostic (2.72e-1)" "unprognostic (4.08e-2)" "unprognostic (8.93e-3)" "unprognostic (1.15e-2)" "unprognostic (1.79e-1)" "unprognostic (1.92e-3)" "potential prognostic unfavorable (4.20e-4)" "unprognostic (1.40e-1)" "unprognostic (2.90e-3)" "potential prognostic unfavorable (5.88e-5)" "unprognostic (1.38e-1)" "unprognostic (1.16e-1)" "unprognostic (4.30e-2)" "unprognostic (1.86e-2)" "unprognostic (4.96e-1)" "unprognostic (5.94e-2)" "unprognostic (6.39e-2)" "unprognostic (1.00e-1)" "unprognostic (2.84e-3)" "unprognostic (2.80e-1)" "unprognostic (3.10e-2)" "unprognostic (4.41e-2)" "unprognostic (1.81e-1)" "unprognostic (2.81e-2)" "unprognostic (1.00e-2)" "unprognostic (2.31e-2)" "unprognostic (1.83e-1)" REM1 "GES, REM" ENSG00000088320 "RRAD and GEM like GTPase 1" O75628 20 31475288-31484895 "Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 22.6" "Cell type enhanced" "Detected in some" "Decidual stromal cells: 38.0;Endometrial stromal cells: 6.5;Epicardial cells: 6.8;Fallopian secretory cells: 11.9;Fallopian tube ciliated cells: 15.7;Fibroblasts: 7.3;Hepatic stellate cells: 6.5;Pericytes: 59.4;Peritubular myoid cells: 13.9;Schwann cells: 7.2;Vascular smooth muscle cells: 22.8" "Group enriched" "Detected in some" 14 "pericyte: 77.3;vascular associated smooth muscle cell: 26.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "skin cancer: 3.5" "Breast - Endothelial cells, Colon - Enteric glia cells, Liver - Hepatic stellate cells, Pituitary gland - Fibroblasts, Stomach - Fibroblasts" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebellum: 6.2" HPA049821 Approved NA NA "Cluster 75: Ovary - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 69: Skin cancer - ECM organization" "Cluster 110: Mural cells - ECM organization" 1 "HPA049821: " "unprognostic (1.75e-2)" "unprognostic (6.69e-2)" "unprognostic (5.40e-2)" "potential prognostic favorable (2.86e-5)" "unprognostic (2.05e-1)" "unprognostic (1.63e-2)" "unprognostic (1.36e-2)" "unprognostic (1.00e-2)" "unprognostic (1.61e-1)" "unprognostic (3.90e-3)" "unprognostic (1.12e-2)" "unprognostic (1.77e-1)" "unprognostic (1.86e-1)" "unprognostic (1.60e-2)" "unprognostic (9.59e-2)" "unprognostic (1.11e-2)" "unprognostic (2.57e-2)" "unprognostic (1.85e-2)" "unprognostic (6.04e-2)" "unprognostic (2.78e-2)" "unprognostic (1.74e-1)" "unprognostic (1.30e-1)" "unprognostic (5.62e-2)" REM2 FLJ38964 ENSG00000139890 "RRAD and GEM like GTPase 2" Q8IYK8 14 22883222-22887678 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 9.3;brain: 7.8" "Cell type enhanced" "Detected in many" "Early spermatids: 38.2;Endometrial ciliated cells: 10.2;Epididymal efferent duct ciliated cells: 8.8;Late spermatids: 13.5;Neutrophils: 21.1;Pancreatic islet cells: 7.5" "Group enriched" "Detected in some" 4 "choroid plexus epithelial cell: 7.9;ependymal cell: 6.5;medium spiny neuron: 2.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 3.7" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in some" "Adipose visceral - Neutrophils, Spleen - Neutrophils_2, Testis - Late spermatids" "Region enhanced" "Detected in all" "basal ganglia: 44.8" "Low region specificity" "Detected in all" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 24: Neutrophils - Innate immunity signal integration" 2 "unprognostic (2.85e-2)" "unprognostic (1.31e-2)" "unprognostic (3.08e-3)" "unprognostic (3.05e-1)" "unprognostic (5.33e-2)" "unprognostic (8.73e-2)" "unprognostic (2.12e-2)" "potential prognostic favorable (6.27e-5)" "unprognostic (3.17e-2)" "unprognostic (1.40e-1)" REN ENSG00000143839 Renin P00797 1 204154819-204190324 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Aspartyl protease, Hydrolase, Protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "kidney: 134.7" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 38.4;Early spermatids: 27.1;Endometrial luminal cells: 27.0;Late spermatids: 58.5;Pericytes: 58.8;Prostatic club cells: 23.2;Sertoli cells: 13.7;Urothelial cells: 17.5" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 16.8;ependymal cell: 7.2" "Cancer enriched" "Detected in many" 9 "Kidney Renal Clear Cell Carcinoma (TCGA): 94.7" "Region enhanced" "Detected in many" "choroid plexus: 7.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Bladder cancer: 22.1;colorectal cancer: 8.4" "Lung - Alveolar cells type 2, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA005131 Approved "Secreted to blood" Enzyme NA NA 692000 28000 "Cluster 72: Kidney - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 108: Fibroblasts - ECM organization" 5 "HPA005131: " "unprognostic (6.94e-2)" "unprognostic (1.19e-2)" "unprognostic (1.18e-1)" "unprognostic (2.37e-1)" "unprognostic (1.77e-1)" "potential prognostic favorable (8.68e-6)" "unprognostic (2.00e-2)" "potential prognostic unfavorable (3.47e-5)" "unprognostic (2.05e-2)" "unprognostic (1.63e-1)" "unprognostic (1.42e-1)" "unprognostic (1.72e-2)" "unprognostic (2.18e-2)" "unprognostic (1.13e-1)" "unprognostic (5.58e-3)" "unprognostic (2.11e-1)" "unprognostic (1.33e-1)" "unprognostic (2.25e-1)" RENBP "RBP, RNBP" ENSG00000102032 "Renin binding protein" P51606 X 153935269-153944687 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 42.7;lymphoid tissue: 68.0" "Cell type enhanced" "Detected in many" "Hofbauer cells: 301.2;Kupffer cells: 87.1;Macrophages: 47.9;Mast cells: 98.0;Megakaryocytes: 49.5;Melanocytes: 52.1;Neutrophils: 35.6;Platelets: 62.1" "Cell type enhanced" "Detected in many" "astrocyte: 19.5;central nervous system macrophage: 22.2" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 123.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 2.7" "Group enriched" "Detected in many" 4 "granulocytes: 2.7;monocytes: 1.6" "Group enriched" "Detected in many" 7 "Leukemia: 20.6;Myeloma: 18.2;skin cancer: 59.5" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Macrophages, Minor Salivary Gland - Macrophages, Skeletal muscle - Macrophages, Skin - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000428, HPA000522" Enhanced NA NA 5000 "Cluster 19: Eosinophils - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 27: Non-specific - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" "HPA000428: , HPA000522: " "unprognostic (1.81e-1)" "unprognostic (3.00e-1)" "unprognostic (1.70e-1)" "potential prognostic favorable (2.42e-5)" "unprognostic (1.18e-1)" "unprognostic (9.60e-3)" "unprognostic (4.53e-3)" "unprognostic (1.21e-2)" "unprognostic (1.55e-1)" "unprognostic (1.39e-2)" "potential prognostic favorable (2.66e-4)" "unprognostic (2.69e-2)" "unprognostic (5.54e-2)" "unprognostic (2.30e-2)" "unprognostic (2.07e-1)" "potential prognostic favorable (3.26e-4)" "unprognostic (3.60e-2)" "unprognostic (1.55e-1)" "unprognostic (1.60e-1)" "unprognostic (1.20e-1)" "unprognostic (3.89e-2)" "unprognostic (2.14e-2)" "unprognostic (8.90e-2)" "unprognostic (1.40e-1)" "unprognostic (3.56e-2)" "unprognostic (1.41e-2)" "unprognostic (2.74e-2)" "unprognostic (8.01e-3)" "unprognostic (2.71e-2)" "unprognostic (6.88e-2)" "unprognostic (2.43e-2)" REP15 RAB15EP ENSG00000174236 "RAB15 effector protein" Q6BDI9 12 27696447-27697596 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 12 "intestine: 55.7;stomach 1: 72.9" "Cell type enriched" "Detected in some" 5 "Goblet cells: 561.8" "Cell type enhanced" "Detected in many" "endothelial cell: 7.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "testis cancer: 11.6" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA040448, HPA059868" Approved NA NA "Cluster 77: Intestine - Digestion" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 70: Intestinal goblet cells - Mucin production" 11 "HPA040448: , HPA059868: " "unprognostic (2.17e-2)" "unprognostic (1.12e-1)" "unprognostic (1.09e-2)" "unprognostic (9.80e-3)" "unprognostic (5.49e-3)" "unprognostic (7.52e-2)" "unprognostic (1.56e-1)" "potential prognostic favorable (1.85e-6)" "unprognostic (4.66e-2)" "potential prognostic favorable (2.82e-4)" "unprognostic (3.06e-1)" "unprognostic (4.74e-2)" "potential prognostic unfavorable (1.79e-4)" "unprognostic (8.44e-3)" "unprognostic (2.05e-1)" "unprognostic (1.46e-3)" "unprognostic (8.60e-2)" "unprognostic (1.31e-2)" "unprognostic (9.27e-2)" "unprognostic (1.66e-1)" "unprognostic (9.41e-2)" "unprognostic (1.11e-3)" "unprognostic (8.21e-2)" "unprognostic (8.54e-2)" "unprognostic (1.56e-1)" "unprognostic (7.32e-3)" "unprognostic (4.58e-3)" REPIN1 "AP4, H_DJ0584D14.12, RIP60, Zfp464, ZNF464" ENSG00000214022 "Replication initiator 1" Q9BWE0 7 150368189-150374044 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Adipocytes: 5.1;Cardiomyocytes: 2.7" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 7.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036022 Approved Supported Nucleoplasm NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 18: Non-specific - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 89: Adipocytes - Lipid metabolism" 11 Nucleoplasm "HPA036022: " "unprognostic (1.15e-2)" "unprognostic (2.97e-2)" "unprognostic (8.75e-2)" "unprognostic (6.65e-2)" "unprognostic (2.96e-1)" "unprognostic (6.95e-2)" "unprognostic (2.53e-2)" "unprognostic (7.71e-2)" "unprognostic (1.38e-2)" "unprognostic (2.18e-1)" "unprognostic (1.49e-1)" "unprognostic (9.15e-2)" "unprognostic (6.72e-2)" "unprognostic (3.99e-2)" "unprognostic (1.04e-2)" "unprognostic (9.38e-2)" "unprognostic (9.32e-3)" "unprognostic (1.02e-1)" "unprognostic (2.86e-1)" "unprognostic (1.23e-1)" "unprognostic (1.56e-1)" "unprognostic (3.47e-3)" "potential prognostic favorable (2.66e-4)" "unprognostic (6.23e-3)" "unprognostic (3.31e-2)" "unprognostic (2.20e-1)" "unprognostic (4.36e-2)" "unprognostic (2.26e-3)" "unprognostic (7.66e-2)" "unprognostic (6.59e-3)" "unprognostic (2.22e-2)" REPS1 ENSG00000135597 "RALBP1 associated Eps domain containing 1" Q96D71 6 138903493-138988261 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Bergmann glia: 402.6;Lactotrophs: 451.6;Sertoli cells: 444.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029961, HPA029962, HPA029963" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 22: Epididymis - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 28: Non-specific - Nuclear processes" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 11 "Plasma membrane" "Vesicles, Cytosol" "HPA029961: , HPA029962: , HPA029963: " "unprognostic (1.91e-1)" "potential prognostic unfavorable (2.84e-5)" "unprognostic (2.17e-1)" "unprognostic (1.25e-1)" "unprognostic (7.91e-3)" "unprognostic (4.72e-2)" "unprognostic (2.59e-3)" "unprognostic (7.11e-2)" "unprognostic (6.22e-2)" "unprognostic (4.15e-2)" "potential prognostic favorable (2.50e-4)" "unprognostic (4.67e-2)" "unprognostic (1.85e-1)" "unprognostic (1.12e-3)" "unprognostic (1.57e-1)" "unprognostic (2.54e-1)" "unprognostic (1.13e-1)" "unprognostic (4.91e-2)" "unprognostic (1.29e-1)" "unprognostic (1.12e-2)" "unprognostic (9.86e-2)" "unprognostic (2.05e-2)" "unprognostic (7.33e-3)" "unprognostic (2.54e-1)" "unprognostic (9.53e-3)" "unprognostic (4.16e-2)" "unprognostic (2.71e-1)" "unprognostic (1.47e-1)" "unprognostic (1.64e-1)" "unprognostic (1.99e-1)" "unprognostic (9.52e-2)" REPS2 POB1 ENSG00000169891 "RALBP1 associated Eps domain containing 2" Q8NFH8 X 16946658-17153272 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Neutrophils: 1059.9" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 25.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 16 "basophil: 5.8;eosinophil: 4.5;neutrophil: 14.3" "Lineage enriched" "Detected in single" 28 "granulocytes: 14.3" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Lung - Alveolar cells type 1, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000565, HPA026073" Uncertain NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 36: Brain & Liver - Signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 14 "HPA000565: , HPA026073: " "unprognostic (1.02e-1)" "unprognostic (1.86e-1)" "unprognostic (8.64e-2)" "unprognostic (5.98e-2)" "unprognostic (4.62e-2)" "unprognostic (1.15e-2)" "unprognostic (2.12e-1)" "potential prognostic favorable (8.98e-5)" "unprognostic (1.77e-2)" "potential prognostic favorable (1.60e-5)" "unprognostic (1.04e-1)" "unprognostic (8.47e-3)" "unprognostic (1.74e-3)" "potential prognostic favorable (3.79e-4)" "unprognostic (2.44e-2)" "unprognostic (7.10e-2)" "unprognostic (3.01e-1)" "unprognostic (1.50e-1)" "unprognostic (5.47e-3)" "unprognostic (1.88e-2)" "potential prognostic unfavorable (2.91e-4)" "unprognostic (4.41e-3)" "unprognostic (2.64e-1)" "potential prognostic favorable (9.29e-4)" "unprognostic (1.25e-1)" "unprognostic (4.76e-2)" "unprognostic (7.13e-2)" "unprognostic (1.07e-1)" "unprognostic (2.11e-2)" "unprognostic (4.54e-1)" RER1 ENSG00000157916 "Retention in endoplasmic reticulum sorting receptor 1" O15258 1 2391775-2405442 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1550.1;Late primary spermatocytes: 593.7;Late spermatids: 653.0;Syncytiotrophoblasts: 612.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037240, HPA051400" Supported Supported "Golgi apparatus" No No "Cluster 42: Non-specific - Vesicular transport" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 37: Non-specific - mRNA processing" "Cluster 84: Apical squamous epithelium - Cornification" 74 "Golgi apparatus" "CAB037240: , HPA051400: " "unprognostic (1.62e-2)" "unprognostic (1.95e-1)" "unprognostic (7.22e-2)" "unprognostic (3.41e-3)" "potential prognostic favorable (1.19e-4)" "unprognostic (9.73e-2)" "unprognostic (1.83e-1)" "unprognostic (2.97e-1)" "unprognostic (6.63e-3)" "potential prognostic unfavorable (2.15e-4)" "potential prognostic favorable (3.32e-4)" "unprognostic (2.51e-1)" "unprognostic (4.48e-1)" "unprognostic (3.59e-3)" "unprognostic (1.39e-3)" "unprognostic (1.53e-2)" "unprognostic (2.50e-2)" "unprognostic (9.31e-2)" "unprognostic (9.66e-2)" "unprognostic (3.75e-1)" "unprognostic (1.56e-1)" "unprognostic (3.95e-3)" "unprognostic (1.34e-1)" "unprognostic (2.49e-1)" "unprognostic (1.09e-1)" "unprognostic (3.42e-1)" "unprognostic (1.97e-1)" "unprognostic (1.55e-1)" "unprognostic (2.35e-2)" "unprognostic (4.44e-1)" "unprognostic (1.65e-1)" RERE "ARG, ARP, ATN1L, ATN2, DNB1, KIAA0458" ENSG00000142599 "Arginine-glutamic acid dipeptide repeats" Q9P2R6 1 8352397-8848921 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, Repressor" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024093 Uncertain Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 17 "Nuclear bodies" Nucleoplasm "HPA024093: " "unprognostic (1.77e-2)" "unprognostic (2.11e-1)" "unprognostic (1.85e-2)" "unprognostic (7.29e-3)" "unprognostic (2.03e-2)" "unprognostic (3.38e-2)" "unprognostic (2.56e-1)" "potential prognostic favorable (8.83e-4)" "unprognostic (1.16e-2)" "unprognostic (1.16e-2)" "potential prognostic favorable (3.39e-6)" "unprognostic (2.51e-3)" "unprognostic (3.27e-2)" "potential prognostic unfavorable (2.81e-4)" "unprognostic (8.13e-2)" "unprognostic (3.78e-2)" "unprognostic (1.87e-1)" "unprognostic (4.03e-2)" "unprognostic (2.08e-1)" "unprognostic (9.96e-2)" "unprognostic (1.89e-1)" "unprognostic (1.23e-1)" "unprognostic (9.75e-3)" "unprognostic (2.62e-1)" "unprognostic (2.26e-1)" "unprognostic (4.37e-3)" "unprognostic (5.19e-2)" "unprognostic (3.02e-1)" "unprognostic (1.59e-1)" "unprognostic (3.81e-1)" "unprognostic (1.75e-1)" RERG MGC15754 ENSG00000134533 "RAS like estrogen regulated growth inhibitor" Q96A58 12 15107783-15348675 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 401.4;Mesothelial cells: 412.0;Pericytes: 407.0;Podocytes: 1212.0;Proximal tubule cells: 508.1;Salivary ionocytes: 493.3" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Breast Invasive Carcinoma (TCGA): 63.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 25.3;Rhabdoid: 31.9" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041387 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 24: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 110: Mural cells - ECM organization" 1 "Nucleoplasm, Cytosol" "Nucleoli fibrillar center" "HPA041387: " "unprognostic (4.47e-2)" "unprognostic (1.12e-1)" "unprognostic (1.31e-1)" "unprognostic (2.58e-1)" "unprognostic (4.32e-2)" "unprognostic (3.94e-1)" "unprognostic (1.31e-1)" "unprognostic (4.91e-2)" "unprognostic (2.70e-3)" "unprognostic (2.77e-2)" "potential prognostic favorable (2.97e-4)" "unprognostic (2.42e-2)" "unprognostic (1.16e-2)" "unprognostic (1.62e-1)" "unprognostic (1.98e-1)" "unprognostic (1.69e-2)" "unprognostic (3.44e-1)" "unprognostic (1.41e-1)" "unprognostic (1.36e-1)" "unprognostic (1.54e-2)" "unprognostic (2.52e-1)" "unprognostic (6.53e-2)" "unprognostic (1.01e-1)" "unprognostic (2.41e-1)" "unprognostic (2.31e-1)" "unprognostic (7.49e-2)" "unprognostic (2.28e-2)" "unprognostic (1.09e-3)" "unprognostic (8.12e-2)" "unprognostic (4.69e-1)" "unprognostic (2.29e-2)" RERGL FLJ22655 ENSG00000111404 "RERG like" Q9H628 12 18080869-18320107 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 4 "blood vessel: 166.7" "Cell type enriched" "Detected in many" 18 "Vascular smooth muscle cells: 850.4" "Group enriched" "Detected in many" 5 "pericyte: 799.9;vascular associated smooth muscle cell: 330.2" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 6.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 4.0;Sarcoma: 3.2" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Heart muscle - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Thyroid gland - Smooth muscle cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA041740 Uncertain Approved Nucleoplasm NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 47: Endothelial cells - Vasculature" "Cluster 5: Rhabdoid - Unknown function" "Cluster 62: Smooth muscle cells - Muscle contraction" Nucleoplasm "HPA041740: " "unprognostic (1.24e-1)" "unprognostic (5.94e-2)" "unprognostic (1.18e-2)" "unprognostic (1.75e-1)" "validated prognostic favorable (5.69e-5)" "validated prognostic favorable (2.94e-6)" "unprognostic (2.67e-3)" "potential prognostic favorable (5.51e-4)" "unprognostic (1.61e-2)" "unprognostic (7.20e-2)" "unprognostic (1.14e-1)" "unprognostic (1.72e-1)" "unprognostic (8.36e-3)" "unprognostic (3.00e-2)" "unprognostic (3.15e-1)" "unprognostic (1.70e-2)" RESF1 "C12orf35, FLJ10652, FLJ20696, GET, KIAA1551, UTA2-1" ENSG00000174718 "Retroelement silencing factor 1" Q9HCM1 12 31959370-31993107 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 65.6;ovary: 65.3" "Cell type enriched" "Detected in many" 6 "Neutrophils: 2511.5" "Cell type enhanced" "Detected in all" "leukocyte: 510.8" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 82.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 214.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 214.7" "Cancer enhanced" "Detected in all" "testis cancer: 104.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013816, HPA015622" Approved Supported "Nucleoli,Nucleoli rim,Intermediate filaments,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 61: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 24: Neutrophils - Innate immunity signal integration" 3 "Nucleoli, Nucleoli rim" "Intermediate filaments, Cytosol" "HPA013816: , HPA015622: " "unprognostic (2.93e-2)" "unprognostic (1.88e-1)" "unprognostic (1.39e-1)" "unprognostic (9.28e-2)" "unprognostic (3.97e-2)" "unprognostic (1.69e-1)" "unprognostic (8.89e-2)" "unprognostic (3.12e-2)" "unprognostic (4.54e-2)" "potential prognostic favorable (2.40e-4)" "unprognostic (4.11e-2)" "potential prognostic unfavorable (2.02e-5)" "unprognostic (1.31e-1)" "unprognostic (3.06e-1)" "unprognostic (4.19e-2)" "unprognostic (3.20e-1)" "unprognostic (5.27e-2)" "unprognostic (2.44e-2)" "unprognostic (1.41e-1)" "unprognostic (4.57e-2)" "unprognostic (3.35e-2)" "unprognostic (7.47e-2)" "unprognostic (1.41e-3)" "unprognostic (5.04e-2)" "unprognostic (7.23e-2)" "unprognostic (1.78e-1)" "unprognostic (1.89e-1)" "unprognostic (1.62e-1)" "unprognostic (1.90e-1)" RESP18 ENSG00000182698 "Regulated endocrine specific protein 18" Q5W5W9 2 219327407-219333177 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 42 "brain: 46.4" "Cell type enriched" "Detected in some" 5 "Late spermatids: 56.1" "Cell type enhanced" "Detected in many" "hippocampal CA4: 8.4;lower rhombic lip: 5.4" "Not detected" "Not detected" "Region enhanced" "Detected in many" "basal ganglia: 28.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" REST "DFNA27, NRSF, XBR" ENSG00000084093 "RE1 silencing transcription factor" Q13127 4 56907876-56966808 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Repressor "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 68.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006079, CAB068222" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 8: Immune cells - Immune response" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 31 Nucleoplasm Cytosol "CAB068222: , HPA006079: " "unprognostic (1.17e-1)" "unprognostic (8.81e-3)" "unprognostic (1.43e-2)" "unprognostic (4.38e-3)" "unprognostic (2.08e-1)" "unprognostic (3.61e-2)" "unprognostic (1.34e-1)" "unprognostic (1.18e-1)" "unprognostic (1.42e-1)" "unprognostic (5.67e-2)" "potential prognostic favorable (8.84e-7)" "unprognostic (1.76e-3)" "unprognostic (1.17e-1)" "unprognostic (7.28e-3)" "unprognostic (1.99e-1)" "unprognostic (3.75e-2)" "unprognostic (3.60e-2)" "unprognostic (2.06e-1)" "unprognostic (6.02e-2)" "unprognostic (2.35e-1)" "unprognostic (4.85e-3)" "unprognostic (3.09e-3)" "unprognostic (1.03e-2)" "unprognostic (9.16e-2)" "unprognostic (2.65e-2)" "unprognostic (1.10e-1)" "unprognostic (7.92e-3)" "unprognostic (5.47e-2)" "unprognostic (1.44e-1)" "unprognostic (1.70e-1)" "unprognostic (3.49e-2)" RET "CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51" ENSG00000165731 "Ret proto-oncogene" P07949 10 43077064-43130351 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Hirschsprung disease, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 10.9;parathyroid gland: 18.7" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 234.0;Breast lactating cells: 62.8;Corticotrophs: 36.2;Fibro-adipogenic progenitors: 52.0;Myosatellite cells: 24.1;Respiratory ionocytes: 86.4;Retinal horizontal cells: 86.1" "Cell type enhanced" "Detected in many" "lower rhombic lip: 23.0" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 20.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Neuroblastoma: 97.7;thyroid cancer: 31.6" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pituitary gland - Corticotropes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "midbrain: 86.5;spinal cord: 33.3" "CAB002581, HPA008356, HPA008495" Approved Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" No NA 14000000 "Cluster 69: Parathyroid gland - Mixed function" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 53 "Golgi apparatus, Cytosol" "Plasma membrane" "CAB002581: , HPA008356: , HPA008495: " "unprognostic (7.24e-2)" "unprognostic (1.86e-1)" "unprognostic (3.21e-1)" "unprognostic (1.61e-1)" "unprognostic (5.47e-2)" "unprognostic (6.93e-3)" "unprognostic (1.24e-1)" "unprognostic (2.00e-2)" "unprognostic (2.72e-2)" "unprognostic (1.05e-1)" "unprognostic (3.68e-2)" "unprognostic (1.31e-2)" "unprognostic (4.72e-1)" "unprognostic (9.61e-2)" "unprognostic (1.17e-3)" "unprognostic (2.46e-2)" "unprognostic (5.02e-2)" "unprognostic (2.85e-1)" RETN "ADSF, FIZZ3, RETN1" ENSG00000104918 Resistin Q9HD89 19 7669049-7670455 "Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" Hormone "Diabetes mellitus, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "bone marrow: 233.2" "Cell type enriched" "Detected in some" 5 "Neutrophil progenitors: 3157.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 8.4;Pancreatic Adenocarcinoma (TCGA): 10.2" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 8 "classical monocyte: 171.1;intermediate monocyte: 92.0;myeloid DC: 118.9;non-classical monocyte: 47.6" "Group enriched" "Detected in many" 11 "dendritic cells: 118.9;monocytes: 171.1" "Cancer enriched" "Detected in single" 186 "Leukemia: 67.0" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Kidney - Macrophages, Liver - Neutrophils, Prostate - Macrophages, Spleen - Neutrophils_1, Thyroid gland - Neutrophils" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Secreted to blood" Hormone NA NA 5120000 2000000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 15: Bone marrow - Innate immune response" "Cluster 51: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 1 "unprognostic (1.31e-1)" "unprognostic (2.29e-1)" "unprognostic (4.08e-2)" "potential prognostic unfavorable (1.80e-6)" "unprognostic (1.26e-2)" "unprognostic (1.07e-1)" "unprognostic (1.68e-1)" "unprognostic (1.17e-1)" "unprognostic (4.57e-2)" "unprognostic (1.61e-1)" "potential prognostic unfavorable (9.72e-4)" "unprognostic (2.49e-1)" "unprognostic (6.05e-2)" "unprognostic (8.04e-2)" "unprognostic (6.94e-2)" "unprognostic (6.49e-3)" "unprognostic (7.08e-2)" "unprognostic (4.95e-2)" RETNLB "FIZZ2, HXCP2, RELMb" ENSG00000163515 "Resistin like beta" Q9BQ08 3 108743424-108757410 "Predicted secreted proteins, Transporters" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 57 "intestine: 216.7" "Cell type enriched" "Detected in some" 18 "Goblet cells: 178.3" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "Colon Adenocarcinoma (TCGA): 45.8;Rectum Adenocarcinoma (TCGA): 37.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "colorectal cancer: 1.1" "Colon - Colon enterocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA049152 Enhanced Uncertain "Endoplasmic reticulum" "Secreted to blood" Hormone NA NA 123000 "Cluster 17: Intestine - Digestion" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 70: Intestinal goblet cells - Mucin production" "Endoplasmic reticulum" "HPA049152: " "unprognostic (1.27e-2)" "unprognostic (1.93e-2)" "unprognostic (7.74e-1)" "unprognostic (2.63e-1)" "unprognostic (5.00e-3)" "unprognostic (6.79e-3)" "unprognostic (3.86e-2)" RETREG1 "FAM134B, FLJ20152, JK1" ENSG00000154153 "Reticulophagy regulator 1" Q9H6L5 5 16473038-16617101 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Autophagy "Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 94.2;skeletal muscle: 117.5" "Cell type enhanced" "Detected in many" "Early spermatids: 797.7;Endometrial glandular cells: 525.6;Epididymal efferent duct absorptive cells: 436.9;Late spermatids: 1220.6;Myonuclei: 410.4;Podocytes: 806.0;Thymic myoid cells: 874.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 10 "granulocytes: 9.4;T-cells: 8.8" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Minor Salivary Gland - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012077 Supported "Endoplasmic reticulum" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 52: Non-specific - Cellular respiration" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 51: Secretory epithelial cells - Mixed function" 9 "Endoplasmic reticulum" "HPA012077: " "unprognostic (1.60e-1)" "unprognostic (1.16e-1)" "unprognostic (1.10e-1)" "unprognostic (1.32e-1)" "unprognostic (1.29e-3)" "unprognostic (1.08e-2)" "unprognostic (8.69e-2)" "unprognostic (1.48e-2)" "unprognostic (4.21e-1)" "potential prognostic favorable (1.68e-8)" "unprognostic (7.74e-2)" "potential prognostic favorable (5.82e-4)" "unprognostic (2.53e-2)" "unprognostic (4.73e-1)" "unprognostic (2.46e-2)" "unprognostic (3.15e-1)" "unprognostic (4.20e-1)" "unprognostic (1.06e-1)" "unprognostic (8.77e-3)" "unprognostic (2.63e-2)" "unprognostic (9.98e-3)" "unprognostic (3.47e-1)" "unprognostic (1.21e-2)" "unprognostic (2.55e-1)" "unprognostic (6.51e-2)" "unprognostic (2.26e-1)" "unprognostic (9.23e-2)" "unprognostic (1.17e-1)" "unprognostic (1.34e-1)" RETREG2 "C2orf17, FAM134A, MAG-2, MGC3035" ENSG00000144567 "Reticulophagy regulator family member 2" Q8NC44 2 219176225-219185475 "Predicted intracellular proteins, Predicted membrane proteins" Autophagy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 235.9;Late spermatids: 305.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Prostate basal glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011170, HPA011844, HPA075910" Approved Uncertain "Golgi apparatus,Cytosol" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 27: Non-specific - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 4 Cytosol "Golgi apparatus" "HPA011170: , HPA011844: , HPA075910: " "unprognostic (5.90e-2)" "potential prognostic unfavorable (8.28e-4)" "unprognostic (1.33e-1)" "unprognostic (1.73e-1)" "unprognostic (1.72e-2)" "unprognostic (7.44e-3)" "unprognostic (4.02e-2)" "unprognostic (2.44e-2)" "unprognostic (4.71e-2)" "validated prognostic favorable (2.81e-7)" "validated prognostic favorable (6.61e-6)" "unprognostic (1.08e-2)" "potential prognostic unfavorable (1.86e-4)" "unprognostic (1.47e-1)" "unprognostic (6.59e-2)" "unprognostic (2.81e-1)" "unprognostic (1.10e-1)" "unprognostic (8.17e-2)" "unprognostic (1.51e-1)" "unprognostic (8.49e-2)" "unprognostic (2.47e-1)" "unprognostic (4.43e-1)" "unprognostic (6.56e-2)" "unprognostic (7.78e-3)" "unprognostic (3.32e-1)" "unprognostic (1.83e-1)" "unprognostic (7.03e-3)" "unprognostic (2.39e-2)" "unprognostic (1.77e-1)" RETREG3 "DKFZp686B1036, FAM134C, FLJ33806" ENSG00000141699 "Reticulophagy regulator family member 3" Q86VR2 17 42579513-42610623 "Predicted membrane proteins" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 180.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016492 Uncertain Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 21: Testis - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 7: Non-specific - Transcription" 149 "Nucleoplasm, Nuclear membrane" Cytosol "HPA016492: " "unprognostic (2.83e-1)" "unprognostic (2.86e-2)" "unprognostic (7.14e-2)" "unprognostic (1.37e-1)" "potential prognostic unfavorable (7.85e-4)" "unprognostic (5.70e-2)" "unprognostic (2.25e-1)" "unprognostic (1.85e-1)" "unprognostic (3.34e-2)" "unprognostic (1.23e-3)" "unprognostic (4.73e-3)" "unprognostic (3.04e-1)" "unprognostic (3.15e-3)" "unprognostic (2.33e-1)" "unprognostic (2.09e-1)" "unprognostic (3.13e-1)" "unprognostic (3.53e-1)" "unprognostic (2.05e-2)" "unprognostic (6.77e-2)" "unprognostic (1.85e-2)" "unprognostic (3.21e-1)" "unprognostic (1.42e-1)" "unprognostic (4.49e-2)" "unprognostic (5.59e-3)" "unprognostic (1.09e-1)" "unprognostic (2.48e-1)" "unprognostic (1.18e-1)" "unprognostic (3.44e-2)" "unprognostic (2.40e-2)" RETSAT FLJ20296 ENSG00000042445 "Retinol saturase" Q6NUM9 2 85341955-85354531 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 231.9" "Cell type enhanced" "Detected in many" "Adipocytes: 218.4;Colonocytes: 205.9;Enterocytes: 270.5;Foveolar cells: 85.8;Melanocytes: 105.4;Myonuclei: 94.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007961 Uncertain Approved Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 24 Cytosol "HPA007961: " "unprognostic (1.40e-1)" "unprognostic (1.03e-2)" "unprognostic (1.05e-2)" "unprognostic (6.62e-2)" "unprognostic (1.36e-1)" "unprognostic (2.73e-1)" "unprognostic (1.86e-1)" "unprognostic (2.83e-2)" "unprognostic (2.77e-3)" "unprognostic (8.62e-3)" "potential prognostic favorable (1.19e-10)" "unprognostic (6.25e-2)" "unprognostic (1.17e-1)" "unprognostic (1.72e-1)" "unprognostic (6.77e-2)" "unprognostic (1.96e-1)" "unprognostic (1.30e-1)" "unprognostic (1.96e-1)" "unprognostic (1.33e-1)" "unprognostic (2.15e-2)" "unprognostic (3.27e-1)" "potential prognostic unfavorable (7.52e-4)" "unprognostic (2.13e-2)" "unprognostic (6.21e-2)" "unprognostic (2.23e-1)" "unprognostic (2.29e-2)" "unprognostic (1.78e-1)" "unprognostic (2.86e-1)" "unprognostic (1.72e-1)" "unprognostic (6.09e-3)" "unprognostic (2.34e-1)" REV1 REV1L ENSG00000135945 "REV1 DNA directed polymerase" Q9UBZ9 2 99400475-99490035 "Predicted intracellular proteins" "DNA damage, DNA repair, DNA synthesis" "DNA-binding, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008881, HPA044534, HPA051036" Uncertain Supported Nucleoli NA NA "Cluster 63: Non-specific - Basic cellular processes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 56: Non-specific - Sensory perception" "Cluster 7: Non-specific - Transcription" 16 Nucleoli "HPA008881: , HPA044534: , HPA051036: " "unprognostic (2.50e-1)" "unprognostic (1.93e-2)" "unprognostic (1.24e-1)" "unprognostic (3.44e-1)" "unprognostic (6.97e-2)" "unprognostic (6.59e-3)" "unprognostic (2.01e-1)" "unprognostic (6.70e-3)" "unprognostic (3.92e-3)" "unprognostic (2.77e-1)" "validated prognostic favorable (3.39e-6)" "validated prognostic favorable (7.12e-4)" "unprognostic (1.08e-1)" "unprognostic (4.33e-3)" "unprognostic (4.40e-2)" "unprognostic (1.18e-2)" "unprognostic (1.74e-1)" "unprognostic (2.79e-2)" "unprognostic (3.52e-2)" "unprognostic (9.01e-2)" "unprognostic (1.93e-1)" "unprognostic (7.68e-2)" "unprognostic (1.57e-2)" "unprognostic (4.81e-3)" "unprognostic (9.97e-2)" "unprognostic (5.79e-2)" "unprognostic (8.82e-2)" "unprognostic (2.49e-1)" "unprognostic (2.18e-1)" "unprognostic (6.27e-2)" "unprognostic (6.83e-2)" REV3L "POLZ, REV3" ENSG00000009413 "REV3 like, DNA directed polymerase zeta catalytic subunit" O60673 6 111299028-111483715 "Enzymes, Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication" "DNA-binding, DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 24.2" "Cell type enhanced" "Detected in all" "Decidual stromal cells: 1160.8;Endometrial ciliated cells: 1164.6;Endometrial stromal cells: 2273.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Stomach - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064853, HPA069382" Uncertain Approved Nucleoplasm NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 42: Retina - Visual perception" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 28: Non-specific - Nuclear processes" "Cluster 108: Fibroblasts - ECM organization" 7 Nucleoplasm "HPA064853: , HPA069382: " "unprognostic (4.77e-2)" "unprognostic (3.26e-2)" "unprognostic (1.12e-1)" "unprognostic (1.23e-1)" "potential prognostic unfavorable (3.11e-4)" "unprognostic (3.82e-2)" "unprognostic (1.74e-1)" "unprognostic (5.54e-3)" "unprognostic (1.28e-1)" "potential prognostic unfavorable (5.26e-4)" "unprognostic (2.78e-2)" "unprognostic (1.89e-2)" "unprognostic (2.86e-1)" "unprognostic (1.33e-1)" "unprognostic (3.51e-2)" "unprognostic (3.27e-3)" "unprognostic (9.49e-2)" "unprognostic (3.06e-1)" "unprognostic (1.56e-2)" "unprognostic (1.03e-1)" "unprognostic (4.20e-1)" "unprognostic (5.31e-2)" "unprognostic (2.83e-3)" "unprognostic (9.38e-2)" "unprognostic (5.19e-2)" "unprognostic (1.04e-3)" "unprognostic (1.46e-1)" "unprognostic (8.47e-2)" "unprognostic (1.69e-1)" "unprognostic (5.49e-3)" "unprognostic (9.08e-2)" REX1BD "C19orf60, FLJ20850, FLJ30108, FLJ34606, FLJ37391" ENSG00000006015 "Required for excision 1-B domain containing" Q96EN9 19 18588685-18592337 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hofbauer cells: 340.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043414 Approved Approved Vesicles NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 23: Non-specific - Transcription" "Cluster 65: Non-specific - Cell growth & division" 14 Vesicles "HPA043414: " "unprognostic (9.87e-2)" "unprognostic (1.55e-1)" "unprognostic (1.28e-1)" "unprognostic (7.83e-2)" "unprognostic (7.62e-2)" "unprognostic (1.16e-1)" "unprognostic (8.10e-3)" "unprognostic (2.22e-1)" "unprognostic (9.81e-3)" "unprognostic (2.42e-1)" "unprognostic (8.60e-2)" "unprognostic (2.39e-1)" "unprognostic (4.63e-2)" "unprognostic (1.14e-1)" "unprognostic (2.08e-1)" "unprognostic (6.11e-2)" "unprognostic (9.13e-2)" "unprognostic (1.68e-1)" "unprognostic (3.05e-2)" "unprognostic (1.34e-2)" "unprognostic (2.92e-1)" "unprognostic (1.85e-1)" "unprognostic (1.02e-1)" "unprognostic (2.57e-1)" "unprognostic (1.28e-1)" "unprognostic (2.66e-1)" "unprognostic (1.20e-1)" "unprognostic (1.52e-1)" "unprognostic (6.05e-2)" REXO1 "EloA-BP1, KIAA1138, TCEB3BP1" ENSG00000079313 "RNA exonuclease 1 homolog" Q8N1G1 19 1815248-1848483 "Predicted intracellular proteins" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Early spermatids: 210.6;Late spermatids: 314.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042155, HPA042552" Approved Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 67: Testis - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 2 Nucleoplasm "Nuclear bodies" "HPA042155: , HPA042552: " "unprognostic (6.83e-2)" "unprognostic (1.18e-2)" "unprognostic (2.75e-1)" "unprognostic (6.53e-2)" "unprognostic (1.71e-1)" "unprognostic (5.09e-2)" "unprognostic (5.02e-2)" "unprognostic (1.89e-1)" "unprognostic (3.35e-2)" "unprognostic (2.61e-1)" "unprognostic (1.32e-1)" "unprognostic (3.53e-1)" "unprognostic (3.53e-1)" "unprognostic (1.83e-2)" "unprognostic (4.75e-1)" "unprognostic (1.19e-1)" "unprognostic (1.83e-1)" "unprognostic (3.01e-2)" "unprognostic (4.39e-2)" "unprognostic (2.53e-2)" "unprognostic (3.79e-2)" "unprognostic (6.20e-3)" "unprognostic (2.10e-3)" "unprognostic (1.97e-1)" "unprognostic (5.14e-2)" "potential prognostic favorable (1.68e-4)" "unprognostic (3.18e-1)" "unprognostic (4.40e-2)" "unprognostic (1.15e-2)" "unprognostic (7.18e-2)" "unprognostic (1.44e-1)" REXO2 "CGI-114, DKFZP566E144, SFN" ENSG00000076043 "RNA exonuclease 2" Q9Y3B8 11 114439435-114450279 "Predicted intracellular proteins" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 493.8;Esophageal apical cells: 1142.1;Esophageal suprabasal cells: 365.3;Late primary spermatocytes: 377.7;Oocytes: 1068.4;Parietal cells: 572.8;Syncytiotrophoblasts: 374.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038450, HPA038451" Enhanced Supported "Nucleoli,Focal adhesion sites,Mitochondria" NA NA 300000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 35: Non-specific - Mixed function" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 24: Non-specific - Unknown function" "Cluster 108: Fibroblasts - ECM organization" Mitochondria "Nucleoli, Focal adhesion sites" "HPA038450: , HPA038451: " "unprognostic (5.72e-2)" "unprognostic (1.88e-3)" "unprognostic (1.66e-1)" "unprognostic (2.81e-3)" "unprognostic (8.51e-2)" "unprognostic (8.52e-3)" "unprognostic (6.12e-3)" "unprognostic (1.74e-2)" "unprognostic (8.88e-2)" "unprognostic (1.07e-1)" "potential prognostic favorable (4.71e-5)" "unprognostic (2.14e-2)" "unprognostic (2.97e-1)" "potential prognostic unfavorable (3.83e-4)" "unprognostic (1.36e-2)" "unprognostic (6.48e-2)" "unprognostic (5.63e-3)" "unprognostic (7.47e-2)" "unprognostic (4.48e-2)" "unprognostic (2.82e-1)" "unprognostic (4.87e-2)" "potential prognostic unfavorable (3.65e-4)" "unprognostic (2.01e-2)" "unprognostic (5.38e-2)" "unprognostic (4.49e-2)" "unprognostic (8.41e-2)" "unprognostic (2.37e-2)" "unprognostic (9.82e-2)" "unprognostic (1.05e-1)" "unprognostic (1.23e-1)" "unprognostic (1.34e-1)" REXO4 "hPMC2, XPMC2H" ENSG00000148300 "REX4 homolog, 3'-5' exonuclease" Q9GZR2 9 133406059-133418096 "Predicted intracellular proteins" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 15.8;Early spermatids: 26.5;Late spermatids: 69.4;Microglia: 15.6;Oligodendrocytes: 15.9;Podocytes: 15.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047006 Uncertain Supported Nucleoplasm,Nucleoli NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 24: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 80 "Nucleoplasm, Nucleoli" "HPA047006: " "potential prognostic unfavorable (6.99e-4)" "unprognostic (2.71e-3)" "unprognostic (1.61e-1)" "unprognostic (1.54e-1)" "unprognostic (1.86e-1)" "unprognostic (9.15e-2)" "unprognostic (3.70e-1)" "potential prognostic favorable (5.80e-5)" "unprognostic (6.55e-2)" "unprognostic (3.01e-1)" "potential prognostic favorable (1.50e-5)" "unprognostic (1.18e-3)" "unprognostic (3.82e-1)" "validated prognostic unfavorable (8.14e-11)" "validated prognostic unfavorable (1.14e-4)" "unprognostic (1.53e-3)" "unprognostic (1.51e-2)" "unprognostic (1.18e-1)" "unprognostic (1.92e-2)" "unprognostic (1.71e-1)" "unprognostic (1.29e-1)" "unprognostic (6.72e-3)" "unprognostic (2.39e-1)" "potential prognostic unfavorable (3.17e-4)" "unprognostic (6.49e-2)" "unprognostic (1.17e-1)" "unprognostic (2.65e-1)" "unprognostic (7.72e-2)" "unprognostic (7.15e-2)" "unprognostic (7.54e-2)" "unprognostic (6.54e-3)" REXO5 NEF-sp ENSG00000005189 "RNA exonuclease 5" Q96IC2 16 20806429-20849665 "Predicted intracellular proteins" "Exonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "testis: 321.5" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 331.7;Early spermatids: 326.6;Epicardial cells: 450.3;Late primary spermatocytes: 1453.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 15 "basophil: 87.2" "Lineage enriched" "Detected in many" 39 "granulocytes: 87.2" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA040755, HPA040868, HPA066145" Approved Approved "Nuclear membrane,Nucleoli,Endoplasmic reticulum" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 57: Testis - Spermatogenesis" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 47: Leukemia - Hemostasis" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 2 "Nuclear membrane" "Nucleoli, Endoplasmic reticulum" "HPA040755: , HPA040868: , HPA066145: " "unprognostic (1.60e-2)" "unprognostic (3.88e-2)" "unprognostic (6.98e-2)" "unprognostic (4.82e-2)" "unprognostic (1.58e-1)" "unprognostic (3.96e-1)" "potential prognostic favorable (5.81e-5)" "unprognostic (2.03e-3)" "unprognostic (1.92e-3)" "unprognostic (1.78e-1)" "unprognostic (4.99e-2)" "unprognostic (1.17e-1)" "unprognostic (1.17e-1)" "unprognostic (5.52e-2)" "unprognostic (5.21e-2)" "unprognostic (1.07e-2)" "unprognostic (1.38e-2)" "unprognostic (1.19e-1)" "unprognostic (2.80e-1)" "unprognostic (2.65e-1)" "unprognostic (1.34e-1)" "unprognostic (1.09e-1)" "unprognostic (4.89e-2)" "unprognostic (5.76e-2)" "unprognostic (1.44e-1)" "unprognostic (1.01e-1)" "unprognostic (1.03e-1)" "unprognostic (6.92e-2)" "unprognostic (8.43e-2)" RFC1 "A1, MHCBFB, PO-GA, RFC140" ENSG00000035928 "Replication factor C subunit 1" P35251 4 39287456-39366375 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA replication, Transcription, Transcription regulation" "Activator, DNA-binding" Neuropathy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009520, HPA046116, HPA069306" Supported Enhanced Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 50 Nucleoplasm "CAB009520: , HPA046116: , HPA069306: " "unprognostic (7.35e-2)" "unprognostic (6.36e-2)" "unprognostic (1.48e-1)" "unprognostic (2.61e-1)" "unprognostic (1.83e-2)" "unprognostic (2.41e-1)" "unprognostic (8.93e-2)" "unprognostic (1.92e-2)" "unprognostic (3.11e-2)" "potential prognostic unfavorable (1.01e-5)" "validated prognostic favorable (4.73e-6)" "validated prognostic favorable (4.91e-4)" "unprognostic (1.53e-1)" "unprognostic (1.55e-2)" "unprognostic (2.47e-2)" "unprognostic (1.83e-1)" "unprognostic (1.08e-1)" "unprognostic (2.07e-1)" "unprognostic (1.91e-2)" "unprognostic (1.56e-1)" "unprognostic (1.92e-1)" "unprognostic (2.66e-2)" "unprognostic (2.64e-2)" "unprognostic (1.61e-1)" "unprognostic (2.14e-2)" "unprognostic (1.29e-1)" "unprognostic (5.80e-2)" "unprognostic (1.12e-1)" "unprognostic (3.04e-1)" "unprognostic (3.16e-2)" "unprognostic (1.36e-1)" RFC2 "A1, RFC40" ENSG00000049541 "Replication factor C subunit 2" P35250 7 74231499-74254458 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA replication" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 82.7;Esophageal basal cells: 78.3;Migrating cytotrophoblasts: 96.7" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 23.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029493 Approved Supported "Nucleoplasm,Golgi apparatus" NA Yes "Cluster 42: Non-specific - Vesicular transport" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 39: Non-specific - Transcription" "Cluster 27: Non-specific - Cell proliferation" 39 Nucleoplasm "Golgi apparatus" "HPA029493: " "unprognostic (1.67e-1)" "unprognostic (1.42e-1)" "unprognostic (8.16e-2)" "unprognostic (1.50e-3)" "unprognostic (1.65e-1)" "unprognostic (1.68e-1)" "unprognostic (3.45e-3)" "unprognostic (1.77e-2)" "unprognostic (6.99e-2)" "unprognostic (5.46e-3)" "unprognostic (1.11e-3)" "unprognostic (4.56e-2)" "unprognostic (2.29e-1)" "validated prognostic unfavorable (2.96e-5)" "validated prognostic unfavorable (5.20e-5)" "unprognostic (1.02e-3)" "unprognostic (3.78e-3)" "unprognostic (1.88e-3)" "unprognostic (5.11e-1)" "unprognostic (7.06e-2)" "unprognostic (4.24e-2)" "unprognostic (9.72e-3)" "unprognostic (2.05e-3)" "unprognostic (3.23e-3)" "unprognostic (1.64e-2)" "unprognostic (2.09e-2)" "unprognostic (8.99e-3)" "unprognostic (1.92e-1)" "unprognostic (1.26e-1)" "unprognostic (1.39e-1)" "unprognostic (1.04e-1)" RFC3 "MGC5276, RFC38" ENSG00000133119 "Replication factor C subunit 3" P40938 13 33818069-33966558 "Essential proteins, Predicted intracellular proteins" "DNA replication" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 159.0;Early primary spermatocytes: 133.2;Erythrocyte progenitors: 182.3;Undifferentiated spermatogonia: 151.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030149 Approved Supported Nucleoplasm,Vesicles No Yes "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 19: Non-specific - Unknown function" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 51 "Nucleoplasm, Vesicles" "HPA030149: " "unprognostic (3.07e-3)" "unprognostic (5.89e-2)" "unprognostic (2.05e-2)" "unprognostic (5.28e-2)" "unprognostic (1.49e-1)" "unprognostic (1.76e-1)" "unprognostic (2.05e-2)" "unprognostic (3.34e-2)" "unprognostic (2.03e-2)" "potential prognostic unfavorable (4.55e-5)" "potential prognostic favorable (7.14e-5)" "unprognostic (1.15e-1)" "unprognostic (7.24e-2)" "unprognostic (1.73e-2)" "potential prognostic unfavorable (5.97e-5)" "unprognostic (4.37e-3)" "potential prognostic unfavorable (1.23e-4)" "unprognostic (1.50e-1)" "unprognostic (1.73e-1)" "unprognostic (6.49e-2)" "unprognostic (9.73e-2)" "unprognostic (2.89e-2)" "potential prognostic unfavorable (4.05e-4)" "unprognostic (1.56e-1)" "unprognostic (5.54e-2)" "unprognostic (1.23e-3)" "unprognostic (2.91e-3)" "unprognostic (4.21e-2)" "unprognostic (4.69e-1)" "unprognostic (2.91e-1)" "unprognostic (4.43e-2)" RFC4 "A1, RFC37" ENSG00000163918 "Replication factor C subunit 4" P35249 3 186789880-186807058 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "DNA replication" Deafness "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 51.9;Early primary spermatocytes: 99.1;Erythrocyte progenitors: 94.0;Extravillous trophoblasts: 64.6;Late primary spermatocytes: 61.6;Megakaryocyte progenitors: 48.8;Migrating cytotrophoblasts: 57.0;Oocytes: 64.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004557, HPA049123, HPA058507" Enhanced Enhanced Nucleoplasm NA Yes 4200 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 31: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 27: Non-specific - Cell proliferation" 64 Nucleoplasm "CAB004557: , HPA049123: , HPA058507: " "unprognostic (4.16e-1)" "unprognostic (1.36e-1)" "unprognostic (3.75e-1)" "unprognostic (1.19e-1)" "unprognostic (2.52e-1)" "unprognostic (8.36e-2)" "unprognostic (3.61e-2)" "unprognostic (1.66e-2)" "unprognostic (1.68e-2)" "unprognostic (1.36e-2)" "validated prognostic unfavorable (6.30e-5)" "validated prognostic unfavorable (7.03e-5)" "unprognostic (1.00e-2)" "validated prognostic unfavorable (2.00e-6)" "validated prognostic unfavorable (8.96e-7)" "potential prognostic unfavorable (9.34e-4)" "unprognostic (1.43e-3)" "unprognostic (6.97e-3)" "unprognostic (1.53e-3)" "unprognostic (1.31e-2)" "unprognostic (1.23e-1)" "validated prognostic unfavorable (9.44e-4)" "validated prognostic unfavorable (7.75e-5)" "unprognostic (1.21e-1)" "unprognostic (5.28e-2)" "unprognostic (2.48e-1)" "unprognostic (2.71e-2)" "unprognostic (2.33e-3)" "unprognostic (1.20e-1)" "unprognostic (1.50e-1)" "unprognostic (1.03e-1)" RFC5 RFC36 ENSG00000111445 "Replication factor C subunit 5" P40937 12 118013588-118033130 "Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA replication" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 59.5;Esophageal basal cells: 42.3;Extravillous trophoblasts: 39.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041037 Supported Approved Nucleoplasm NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 27: Non-specific - Cell proliferation" 80 Nucleoplasm "HPA041037: " "unprognostic (3.53e-2)" "unprognostic (9.30e-2)" "unprognostic (9.83e-2)" "unprognostic (1.91e-2)" "unprognostic (1.23e-1)" "unprognostic (1.92e-1)" "unprognostic (3.96e-2)" "unprognostic (8.43e-2)" "unprognostic (2.22e-1)" "unprognostic (3.31e-2)" "unprognostic (1.09e-2)" "unprognostic (9.62e-2)" "unprognostic (1.31e-1)" "unprognostic (3.48e-3)" "unprognostic (3.60e-3)" "unprognostic (1.03e-2)" "unprognostic (2.51e-3)" "unprognostic (1.26e-2)" "unprognostic (5.19e-2)" "unprognostic (2.25e-1)" "unprognostic (9.45e-2)" "unprognostic (5.60e-2)" "unprognostic (7.07e-2)" "unprognostic (9.91e-2)" "unprognostic (9.24e-3)" "unprognostic (2.13e-2)" "unprognostic (8.47e-3)" "unprognostic (2.84e-1)" "unprognostic (3.55e-1)" "unprognostic (1.03e-1)" "unprognostic (2.20e-1)" RFESD ENSG00000175449 "Rieske Fe-S domain containing" Q8TAC1 5 95646777-95684773 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 16.8" "Cell type enhanced" "Detected in many" "Adipocytes: 81.4;Erythrocyte progenitors: 138.2;Erythrocytes: 35.0;Late primary spermatocytes: 52.0;Mast cells: 42.1;Oocytes: 179.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB016546 Uncertain Approved Nucleoplasm NA NA 8100 "Cluster 11: T-cells - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 47: Leukemia - Hemostasis" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 2 Nucleoplasm "CAB016546: " "unprognostic (9.21e-3)" "unprognostic (7.54e-2)" "unprognostic (1.31e-1)" "unprognostic (3.38e-3)" "unprognostic (1.28e-1)" "unprognostic (2.66e-1)" "validated prognostic unfavorable (6.47e-4)" "validated prognostic unfavorable (6.04e-5)" "unprognostic (2.85e-2)" "unprognostic (2.91e-2)" "unprognostic (1.22e-2)" "unprognostic (2.17e-2)" "unprognostic (1.91e-1)" "potential prognostic unfavorable (1.63e-6)" "unprognostic (3.04e-1)" "unprognostic (4.14e-2)" "unprognostic (3.93e-3)" "unprognostic (9.64e-2)" "unprognostic (1.80e-1)" "unprognostic (3.58e-1)" "unprognostic (8.77e-3)" "unprognostic (7.21e-2)" "unprognostic (1.88e-1)" "unprognostic (1.11e-1)" "unprognostic (1.57e-1)" "unprognostic (1.89e-2)" "unprognostic (2.80e-1)" "unprognostic (3.10e-2)" "unprognostic (5.67e-2)" "unprognostic (6.62e-2)" "unprognostic (2.39e-1)" RFFL "CARP-2, CARP2, fring, rififylin, RNF189, RNF34L" ENSG00000092871 "Ring finger and FYVE like domain containing E3 ubiquitin protein ligase" Q8WZ73 17 35005990-35089319 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 85.4;Late spermatids: 151.6;Neutrophils: 75.0;Oligodendrocytes: 105.6" "Cell type enhanced" "Detected in all" "oligodendrocyte: 149.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008096, HPA017910, HPA019492" Approved Approved Vesicles NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 55: Lymphoma - Immune response" "Cluster 7: Non-specific - Transcription" 16 Vesicles "CAB008096: , HPA017910: , HPA019492: " "unprognostic (8.82e-2)" "unprognostic (1.23e-2)" "unprognostic (1.25e-1)" "unprognostic (2.62e-1)" "unprognostic (2.44e-2)" "unprognostic (1.09e-2)" "unprognostic (2.36e-1)" "unprognostic (1.03e-3)" "unprognostic (4.27e-1)" "unprognostic (6.08e-2)" "potential prognostic favorable (3.09e-4)" "unprognostic (1.39e-1)" "unprognostic (1.75e-3)" "unprognostic (9.11e-3)" "unprognostic (9.24e-3)" "unprognostic (3.65e-3)" "unprognostic (6.94e-2)" "unprognostic (1.15e-1)" "unprognostic (8.08e-2)" "unprognostic (5.05e-2)" "unprognostic (1.62e-1)" "unprognostic (8.23e-2)" "unprognostic (4.05e-1)" "unprognostic (1.48e-1)" "potential prognostic favorable (8.03e-4)" "unprognostic (6.60e-2)" "unprognostic (1.58e-1)" "unprognostic (2.02e-1)" "unprognostic (4.17e-2)" "unprognostic (4.97e-2)" "unprognostic (1.22e-1)" RFK "FLJ11149, RIFK" ENSG00000135002 "Riboflavin kinase" Q969G6 9 76385526-76394517 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 202.8;Extravillous trophoblasts: 489.6;Migrating cytotrophoblasts: 238.2;Parietal cells: 173.3;Syncytiotrophoblasts: 164.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023259, CAB033887, HPA057163" Approved Supported "Golgi apparatus" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 1: Neurons - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 3 "Golgi apparatus" "CAB033887: , HPA023259: , HPA057163: " "unprognostic (7.01e-3)" "unprognostic (1.03e-1)" "unprognostic (1.32e-1)" "unprognostic (5.64e-2)" "unprognostic (4.73e-3)" "unprognostic (1.13e-1)" "unprognostic (1.57e-2)" "unprognostic (5.88e-2)" "unprognostic (1.10e-3)" "unprognostic (1.07e-1)" "potential prognostic favorable (6.31e-8)" "unprognostic (1.35e-2)" "unprognostic (1.09e-2)" "unprognostic (1.46e-3)" "unprognostic (6.90e-3)" "unprognostic (1.86e-1)" "unprognostic (1.25e-1)" "unprognostic (1.40e-1)" "unprognostic (2.96e-1)" "unprognostic (3.32e-2)" "unprognostic (6.50e-2)" "unprognostic (1.33e-1)" "unprognostic (6.17e-2)" "unprognostic (3.48e-1)" "unprognostic (2.07e-1)" "unprognostic (6.37e-2)" "unprognostic (1.22e-1)" "unprognostic (4.05e-2)" "unprognostic (1.17e-1)" "unprognostic (2.14e-1)" "unprognostic (5.57e-2)" RFLNA "Cfm2, FAM101A, FLJ44614, RefilinA" ENSG00000178882 "Refilin A" Q6ZTI6 12 123973241-124316024 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "stomach 1: 89.4" "Cell type enhanced" "Detected in many" "Bergmann glia: 191.8;Brain excitatory neurons: 66.1;Brain inhibitory neurons: 74.1;Early spermatids: 89.6;Epicardial cells: 84.1;Foveolar cells: 165.2;Goblet cells: 62.1;Late spermatids: 82.7;Oligodendrocyte progenitor cells: 65.4;Other brain neurons: 63.0" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Colon Adenocarcinoma (TCGA): 19.9;Pancreatic Adenocarcinoma (TCGA): 23.9;Rectum Adenocarcinoma (TCGA): 21.2;Stomach Adenocarcinoma (TCGA): 34.7;Testicular Germ Cell Tumor (TCGA): 10.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Kidney - Fibroblasts, Skeletal muscle - Skeletal myocytes, Stomach - Gastric mucous cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA078021 Enhanced Approved "Focal adhesion sites" NA NA "Cluster 17: Intestine - Digestion" "Cluster 49: Hindbrain - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 68: Foveolar cells - Mucosal defense" "Focal adhesion sites" "HPA078021: " "unprognostic (3.11e-1)" "unprognostic (1.43e-1)" "unprognostic (3.93e-3)" "unprognostic (2.06e-1)" "potential prognostic unfavorable (2.93e-5)" "unprognostic (5.80e-2)" "unprognostic (1.80e-3)" "potential prognostic unfavorable (7.68e-4)" "validated prognostic unfavorable (1.43e-5)" "validated prognostic unfavorable (5.24e-5)" "unprognostic (2.32e-1)" "potential prognostic unfavorable (5.81e-4)" "unprognostic (2.80e-2)" "unprognostic (8.46e-3)" "unprognostic (7.27e-2)" "unprognostic (6.60e-2)" "unprognostic (2.51e-2)" "potential prognostic unfavorable (8.13e-4)" "unprognostic (6.35e-3)" "potential prognostic favorable (6.15e-4)" "unprognostic (1.16e-1)" "unprognostic (5.41e-2)" "unprognostic (1.60e-1)" "unprognostic (1.80e-1)" "unprognostic (1.05e-1)" "unprognostic (2.14e-1)" RFLNB "Cfm1, FAM101B, MGC45871, RefilinB" ENSG00000183688 "Refilin B" Q8N5W9 17 439978-445939 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 73.5" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 17.5;Ependymal cells: 5.0;Innate lymphoid cells: 3.0;Megakaryocyte progenitors: 3.9;Monocyte progenitors: 3.9;Neutrophil progenitors: 10.3;Neutrophils: 5.5;Other brain neurons: 3.7;Podocytes: 11.1;T-cells: 3.6" "Group enriched" "Detected in many" 4 "choroid plexus epithelial cell: 21.9;leukocyte: 39.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 202.1" "Lineage enriched" "Detected in many" 21 "granulocytes: 202.1" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 58.5" "Adrenal gland - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Pituitary gland - Endothelial cells, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030879, HPA060388" Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 8: Immune cells - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 102: Non-specific - Mixed function" 2 "Actin filaments" "Plasma membrane, Cytosol" "HPA030879: , HPA060388: " "unprognostic (1.15e-1)" "unprognostic (1.17e-1)" "unprognostic (6.09e-2)" "unprognostic (1.10e-1)" "unprognostic (1.27e-1)" "unprognostic (1.24e-2)" "unprognostic (3.90e-1)" "unprognostic (1.79e-1)" "unprognostic (6.00e-3)" "potential prognostic favorable (7.07e-5)" "unprognostic (3.58e-3)" "potential prognostic unfavorable (3.42e-5)" "unprognostic (4.30e-1)" "unprognostic (1.84e-1)" "unprognostic (1.01e-1)" "unprognostic (2.13e-2)" "unprognostic (6.33e-2)" "unprognostic (4.81e-2)" "unprognostic (9.09e-2)" "unprognostic (1.87e-2)" "unprognostic (1.13e-1)" "unprognostic (1.16e-1)" "unprognostic (1.19e-1)" "unprognostic (2.68e-1)" "unprognostic (9.34e-2)" "unprognostic (3.44e-2)" "unprognostic (8.69e-2)" "unprognostic (1.16e-1)" "unprognostic (7.14e-2)" RFNG ENSG00000169733 "RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase" Q9Y644 17 82047902-82051831 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 70.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011564, HPA031673" Uncertain Approved Nucleoplasm No No 200000 "Cluster 13: Non-specific - Mitochondria" "Cluster 70: Non-specific - Protein processing" "Cluster 27: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 108: Fibroblasts - ECM organization" 1 Nucleoplasm "HPA011564: , HPA031673: " "unprognostic (4.02e-2)" "unprognostic (1.58e-1)" "unprognostic (4.84e-2)" "unprognostic (1.01e-1)" "unprognostic (2.78e-2)" "unprognostic (1.97e-1)" "unprognostic (1.86e-2)" "unprognostic (1.89e-2)" "unprognostic (2.53e-1)" "unprognostic (3.20e-2)" "potential prognostic favorable (2.16e-5)" "unprognostic (1.13e-1)" "unprognostic (1.76e-1)" "unprognostic (2.07e-1)" "unprognostic (1.26e-2)" "unprognostic (4.59e-2)" "unprognostic (2.09e-2)" "unprognostic (9.29e-3)" "unprognostic (2.21e-1)" "unprognostic (4.25e-1)" "unprognostic (3.12e-3)" "unprognostic (1.10e-1)" "unprognostic (1.22e-1)" "potential prognostic favorable (8.50e-4)" "unprognostic (1.70e-2)" "unprognostic (2.71e-3)" "unprognostic (1.14e-2)" "unprognostic (1.14e-2)" "unprognostic (2.87e-1)" "unprognostic (8.76e-2)" "unprognostic (1.26e-1)" RFPL1 RNF78 ENSG00000128250 "Ret finger protein like 1" O75677 22 29438583-29442455 "Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 16.4" "Group enriched" "Detected in some" 6 "Early spermatids: 10.4;Late primary spermatocytes: 2.8;Prostatic glandular cells: 9.5;Retinal ganglion cells: 3.9" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Prostate Adenocarcinoma (TCGA): 1.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Prostate - Prostate glandular cells, Testis - Late spermatids" "HPA048320, HPA072380" Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 1: Neuronal - Visual perception" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" "Nuclear speckles" "Plasma membrane" "HPA048320: , HPA072380: " "unprognostic (2.08e-1)" "unprognostic (4.58e-2)" "unprognostic (2.34e-1)" RFPL2 RNF79 ENSG00000128253 "Ret finger protein like 2" O75678 22 32190435-32205073 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "brain: 4.3;prostate: 3.4" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 12.1;Brain inhibitory neurons: 8.6;Erythrocyte progenitors: 5.5;Other brain neurons: 4.8;Pancreatic islet cells: 4.2;Prostatic glandular cells: 27.4;Retinal amacrine cells: 6.6;Retinal bipolar cells: 3.2" "Cell type enhanced" "Detected in many" "deep-layer near-projecting: 48.3" "Cancer enriched" "Detected in single" 5 "Prostate Adenocarcinoma (TCGA): 3.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "prostate cancer: 1.3" "Prostate - Prostate glandular cells" "HPA046608, HPA048320, HPA072380" Approved Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" "Nuclear speckles" "Plasma membrane" "HPA046608: , HPA048320: , HPA072380: " "unprognostic (1.36e-1)" "unprognostic (1.01e-1)" RFPL3 RNF120 ENSG00000128276 "Ret finger protein like 3" O75679 22 32354885-32361161 "Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "testis: 23.3" "Group enriched" "Detected in some" 5 "Early spermatids: 3.3;Epicardial cells: 4.5;Late primary spermatocytes: 8.1;Undifferentiated spermatogonia: 9.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 2.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Myeloma: 2.1" "HPA048320, HPA072380" Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 8 "Nuclear speckles" "Plasma membrane" "HPA048320: , HPA072380: " "unprognostic (3.30e-2)" "unprognostic (9.10e-3)" "unprognostic (3.52e-1)" RFPL4A "RFPL4, RNF210" ENSG00000223638 "Ret finger protein like 4A" A6NLU0 19 55759097-55763421 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 1.5;liver: 4.2;testis: 1.8" "Cell type enhanced" "Detected in some" "cDC: 1.2;Early spermatids: 2.9;Extravillous trophoblasts: 2.1;Late primary spermatocytes: 1.3;Macrophages: 1.2;Undifferentiated spermatogonia: 2.4" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "Testicular Germ Cell Tumor (TCGA): 3.2" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "classical monocyte: 10.4" "Lineage enhanced" "Detected in many" "monocytes: 10.4" "Cancer enhanced" "Detected in some" "Bone cancer: 7.3" "Liver - Hepatocytes" HPA046368 Uncertain Approved Centrosome,Cytosol NA NA "Cluster 47: Testis - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 82: Dendritic cells - Antigen presentation" 2 "Centrosome, Cytosol" "HPA046368: " "potential prognostic favorable (2.14e-4)" "unprognostic (1.36e-1)" RFPL4AL1 RNF210B ENSG00000229292 "Ret finger protein like 4A like 1" F8VTS6 19 55769118-55773420 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Testicular Germ Cell Tumor (TCGA): 1.4" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "classical monocyte: 1.9" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in some" "Bladder cancer: 1.5;Bone cancer: 2.7" "Not detected" "Not detected" HPA046368 Uncertain Approved Centrosome,Cytosol NA NA "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 82: Dendritic cells - Antigen presentation" "Centrosome, Cytosol" "HPA046368: " "unprognostic (2.64e-1)" RFPL4B RNF211 ENSG00000251258 "Ret finger protein like 4B" Q6ZWI9 6 112347330-112351294 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 4 "testis: 1.5" "Cell type enriched" "Detected in some" 4 "Extravillous trophoblasts: 23.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Testicular Germ Cell Tumor (TCGA): 2.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "Gastric cancer: 12.1;Rhabdoid: 20.8" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA059324, HPA066464" Uncertain NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 4 "HPA059324: , HPA066464: " "unprognostic (3.42e-2)" "unprognostic (7.36e-2)" RFT1 CDG1N ENSG00000163933 "RFT1 homolog" Q96AA3 3 53088483-53130453 "Disease related genes, Essential proteins, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 61.3;Sertoli cells: 30.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060327, HPA069022" Approved Approved Vesicles NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 70: Non-specific - Protein processing" "Cluster 34: Non-specific - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 28 Vesicles "HPA060327: , HPA069022: " "potential prognostic unfavorable (1.97e-4)" "unprognostic (1.17e-1)" "unprognostic (4.02e-1)" "unprognostic (1.92e-1)" "potential prognostic favorable (5.08e-4)" "unprognostic (6.11e-2)" "unprognostic (2.49e-1)" "unprognostic (1.71e-1)" "unprognostic (5.61e-2)" "unprognostic (2.67e-2)" "unprognostic (3.77e-3)" "unprognostic (1.39e-1)" "unprognostic (1.04e-1)" "validated prognostic unfavorable (9.13e-5)" "validated prognostic unfavorable (1.15e-5)" "unprognostic (2.74e-2)" "potential prognostic unfavorable (3.68e-5)" "unprognostic (8.93e-2)" "unprognostic (2.34e-1)" "unprognostic (2.08e-1)" "unprognostic (1.30e-1)" "potential prognostic unfavorable (7.27e-5)" "unprognostic (2.16e-1)" "unprognostic (2.24e-1)" "unprognostic (1.35e-2)" "unprognostic (3.09e-2)" "unprognostic (1.90e-1)" "unprognostic (3.93e-1)" "unprognostic (1.57e-1)" "unprognostic (1.77e-1)" "unprognostic (9.94e-2)" RFTN1 "FLJ23866, KIAA0084, MIG2, Raftlin" ENSG00000131378 "Raftlin, lipid raft linker 1" Q14699 3 16313574-16514026 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 110.0" "Cell type enhanced" "Detected in many" "Adipocytes: 215.4;Alveolar cells type 2: 189.1;B-cells: 173.5;Bergmann glia: 176.7;cDC: 294.2;Endometrial stromal cells: 179.4;Fibro-adipogenic progenitors: 197.9;Hematopoietic stem cells: 193.1;Innate lymphoid cells: 195.9;Mast cells: 190.8;NK-cells: 266.7;pDCs: 350.7;Pericytes: 175.0;T-cells: 231.8;Thymocytes: 177.0" "Cell type enhanced" "Detected in all" "pericyte: 311.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in many" 5 "lymphoma: 164.4" "Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048725, HPA054662" Enhanced NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 82: Dendritic cells - Antigen presentation" 1 "HPA048725: , HPA054662: " "unprognostic (1.75e-2)" "unprognostic (2.73e-1)" "unprognostic (7.55e-2)" "unprognostic (7.52e-2)" "unprognostic (3.96e-2)" "unprognostic (1.66e-1)" "unprognostic (2.14e-1)" "unprognostic (7.25e-2)" "unprognostic (8.63e-3)" "unprognostic (6.05e-2)" "unprognostic (2.09e-3)" "unprognostic (2.95e-3)" "potential prognostic unfavorable (6.05e-5)" "unprognostic (2.09e-1)" "potential prognostic favorable (5.59e-5)" "unprognostic (1.84e-3)" "unprognostic (2.30e-2)" "unprognostic (4.29e-2)" "unprognostic (9.97e-2)" "unprognostic (4.70e-2)" "unprognostic (5.70e-2)" "unprognostic (1.60e-1)" "unprognostic (1.23e-3)" "unprognostic (2.82e-1)" "unprognostic (3.43e-1)" "unprognostic (3.90e-3)" "potential prognostic unfavorable (8.99e-4)" "unprognostic (9.29e-3)" "unprognostic (3.66e-3)" "unprognostic (2.91e-1)" "unprognostic (2.01e-1)" RFTN2 "C2orf11, FLJ30574, Raftlin-2" ENSG00000162944 "Raftlin family member 2" Q52LD8 2 197568224-197676045 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.7" "Cell type enhanced" "Detected in many" "Astrocytes: 255.0;Bergmann glia: 481.7;Early spermatids: 123.0;Ependymal cells: 131.1;Fibro-adipogenic progenitors: 111.2;Late spermatids: 550.4;Melanocytes: 121.6;Oligodendrocyte progenitor cells: 324.3;Oligodendrocytes: 506.4" "Cell type enhanced" "Detected in many" "Bergmann glia: 484.0;committed oligodendrocyte precursor: 377.5;oligodendrocyte: 605.8;oligodendrocyte precursor cell: 412.4" "Cancer enriched" "Detected in many" 5 "Glioblastoma Multiforme (TCGA): 25.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Colon - Enteric glia cells, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035232, HPA043190" Approved Approved "Plasma membrane" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" "Plasma membrane" "HPA035232: , HPA043190: " "unprognostic (3.59e-2)" "unprognostic (2.23e-1)" "unprognostic (3.49e-1)" "unprognostic (2.21e-3)" "potential prognostic unfavorable (3.37e-4)" "unprognostic (2.97e-1)" "unprognostic (8.81e-3)" "unprognostic (3.26e-2)" "unprognostic (3.56e-2)" "unprognostic (8.59e-2)" "validated prognostic favorable (1.30e-5)" "validated prognostic favorable (9.43e-5)" "unprognostic (1.86e-2)" "unprognostic (1.78e-1)" "unprognostic (6.42e-2)" "unprognostic (2.65e-1)" "unprognostic (5.21e-2)" "unprognostic (1.73e-1)" "unprognostic (9.03e-2)" "unprognostic (2.68e-1)" "unprognostic (4.39e-1)" "unprognostic (1.15e-1)" "unprognostic (2.44e-1)" "unprognostic (1.32e-2)" "unprognostic (2.38e-3)" "unprognostic (4.32e-2)" "unprognostic (1.78e-1)" "unprognostic (9.07e-3)" RFWD3 "FANCW, FLJ10520, RNF201" ENSG00000168411 "Ring finger and WD repeat domain 3" Q6PCD5 16 74621399-74666877 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 44.9" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 117.2;Erythrocyte progenitors: 98.0;Monocyte progenitors: 91.4;Neutrophil progenitors: 119.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048258, HPA075649" Approved Enhanced Nucleoplasm,Cytosol No No "Cluster 15: NK-cells - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 27: Non-specific - Cell proliferation" 39 Nucleoplasm Cytosol "HPA048258: , HPA075649: " "unprognostic (2.36e-1)" "unprognostic (4.07e-2)" "unprognostic (4.36e-1)" "unprognostic (2.09e-1)" "unprognostic (1.27e-1)" "unprognostic (3.23e-1)" "unprognostic (3.13e-1)" "unprognostic (5.16e-2)" "unprognostic (3.46e-1)" "unprognostic (1.35e-2)" "potential prognostic favorable (2.81e-4)" "unprognostic (6.99e-2)" "unprognostic (1.60e-2)" "unprognostic (7.70e-3)" "potential prognostic unfavorable (3.90e-4)" "unprognostic (8.19e-3)" "unprognostic (1.88e-2)" "unprognostic (1.80e-1)" "unprognostic (8.03e-3)" "unprognostic (7.82e-2)" "unprognostic (3.78e-3)" "unprognostic (1.55e-2)" "potential prognostic unfavorable (1.50e-5)" "unprognostic (4.81e-2)" "unprognostic (1.68e-2)" "unprognostic (2.64e-1)" "unprognostic (3.97e-2)" "unprognostic (2.88e-1)" "unprognostic (3.00e-1)" "unprognostic (8.03e-2)" "unprognostic (5.57e-2)" RFX1 EF-C ENSG00000132005 "Regulatory factor X1" P22670 19 13961530-14007039 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 27.6;Brain inhibitory neurons: 26.1;Choroid plexus epithelial cells: 25.4;Distal convoluted tubule cells: 27.0;Early spermatids: 35.8;Ependymal cells: 30.3;Late primary spermatocytes: 25.5;Late spermatids: 44.8;Loop of henle epithelial cells: 30.6;Microglia: 24.0;Other brain neurons: 20.8;Papillary tip epithelial cells: 25.7;Podocytes: 22.2;Proximal tubule cells: 34.5;Renal collecting duct intercalated cells: 23.6;Renal collecting duct principal cells: 25.9;Renal connecting tubule cells: 25.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 3.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048722, HPA052966" Approved Enhanced Nucleoplasm,Vesicles NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 67: Testis - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 23: Non-specific - Transcription" "Cluster 102: Non-specific - Mixed function" 23 Nucleoplasm Vesicles "HPA048722: , HPA052966: " "unprognostic (7.53e-2)" "unprognostic (1.14e-1)" "unprognostic (1.95e-1)" "unprognostic (1.45e-1)" "unprognostic (1.61e-1)" "unprognostic (1.61e-1)" "unprognostic (9.24e-2)" "unprognostic (2.68e-1)" "potential prognostic favorable (6.02e-4)" "unprognostic (3.54e-2)" "potential prognostic favorable (1.48e-4)" "unprognostic (5.73e-2)" "unprognostic (1.33e-1)" "unprognostic (1.51e-1)" "unprognostic (6.37e-2)" "unprognostic (3.03e-1)" "unprognostic (1.01e-1)" "unprognostic (1.75e-2)" "unprognostic (5.48e-2)" "unprognostic (1.89e-1)" "potential prognostic favorable (1.59e-4)" "unprognostic (2.63e-2)" "unprognostic (1.99e-1)" "unprognostic (2.39e-1)" "unprognostic (7.36e-2)" "unprognostic (4.46e-2)" "unprognostic (1.24e-1)" "unprognostic (1.70e-1)" "unprognostic (8.05e-2)" "unprognostic (1.01e-1)" RFX2 FLJ14226 ENSG00000087903 "Regulatory factor X2" P48378 19 5993164-6199572 "Predicted intracellular proteins, Transcription factors" "Cilium biogenesis/degradation, Differentiation, Spermatogenesis, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 55.3" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 550.6;Ependymal cells: 666.7;Epicardial cells: 584.5;Neutrophils: 448.7;Respiratory ciliated cells: 732.6;Salivary myoepithelial cells: 452.9" "Group enriched" "Detected in all" 6 "astrocyte: 263.7;Bergmann glia: 399.2;choroid plexus epithelial cell: 364.9;ependymal cell: 729.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "neutrophil: 23.7" "Lineage enriched" "Detected in many" 9 "granulocytes: 23.7" "Low cancer specificity" "Detected in many" "Skeletal muscle - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA048969 Enhanced Approved "Nucleoplasm,Golgi apparatus,Primary cilium,Basal body,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 11 "Nucleoplasm, Golgi apparatus" "Primary cilium, Basal body, Cytosol" "HPA048969: " "unprognostic (7.93e-2)" "unprognostic (3.72e-2)" "unprognostic (1.60e-1)" "unprognostic (2.98e-1)" "unprognostic (6.89e-2)" "unprognostic (4.63e-2)" "unprognostic (6.84e-2)" "potential prognostic unfavorable (5.81e-4)" "unprognostic (2.59e-2)" "unprognostic (3.68e-2)" "potential prognostic favorable (3.70e-4)" "unprognostic (4.71e-3)" "unprognostic (3.93e-2)" "unprognostic (8.56e-2)" "unprognostic (2.86e-2)" "unprognostic (4.79e-2)" "unprognostic (3.28e-2)" "unprognostic (6.17e-2)" "unprognostic (1.53e-2)" "unprognostic (2.57e-2)" "unprognostic (1.18e-3)" "unprognostic (2.84e-2)" "unprognostic (3.76e-1)" "unprognostic (1.68e-1)" "unprognostic (1.91e-1)" "unprognostic (8.64e-3)" "unprognostic (2.45e-1)" "unprognostic (1.08e-1)" "unprognostic (4.55e-2)" "unprognostic (6.05e-2)" RFX3 ENSG00000080298 "Regulatory factor X3" P48380 9 3218297-3526004 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 19.8" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 1558.8;Endometrial ciliated cells: 852.2;Ependymal cells: 2321.0;Neuroendocrine cells: 852.7;Respiratory ciliated cells: 1764.7" "Cell type enhanced" "Detected in all" "ependymal cell: 2704.1;hippocampal dentate gyrus: 2844.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035689 Enhanced Supported "Nucleoplasm,Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 29: Forebrain - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" 18 Nucleoplasm "Golgi apparatus, Vesicles, Cytosol" "HPA035689: " "unprognostic (2.31e-1)" "unprognostic (3.25e-3)" "unprognostic (2.30e-1)" "unprognostic (4.84e-1)" "unprognostic (7.52e-3)" "unprognostic (2.02e-2)" "unprognostic (8.33e-2)" "unprognostic (6.26e-2)" "unprognostic (1.72e-1)" "unprognostic (1.13e-1)" "unprognostic (6.36e-3)" "potential prognostic favorable (2.86e-4)" "unprognostic (6.70e-2)" "unprognostic (9.33e-2)" "unprognostic (6.31e-3)" "unprognostic (9.12e-2)" "unprognostic (1.26e-1)" "unprognostic (3.03e-1)" "unprognostic (1.98e-1)" "unprognostic (9.61e-2)" "unprognostic (3.06e-2)" "potential prognostic unfavorable (2.83e-4)" "unprognostic (1.64e-1)" "unprognostic (4.88e-3)" "unprognostic (2.64e-2)" "unprognostic (1.19e-1)" "unprognostic (2.16e-1)" "unprognostic (9.52e-2)" "unprognostic (4.22e-2)" "unprognostic (1.64e-1)" RFX4 ENSG00000111783 "Regulatory factor X4" Q33E94 12 106583004-106762803 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 22.2;testis: 70.2" "Cell type enhanced" "Detected in many" "Astrocytes: 688.3;Bergmann glia: 388.1;Early primary spermatocytes: 200.7;Ependymal cells: 415.8;Late primary spermatocytes: 152.5;Pituitary stem cells: 1319.0;Somatotrophs: 146.9" "Group enriched" "Detected in all" 7 "astrocyte: 1093.3;Bergmann glia: 395.9;ependymal cell: 494.6" "Cancer enriched" "Detected in single" 46 "Glioblastoma Multiforme (TCGA): 46.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050527 Enhanced Approved Nucleoplasm NA NA "Cluster 67: Testis - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 28: Astrocytes - Homeostasis & neuron support" Nucleoplasm "HPA050527: " "unprognostic (4.48e-1)" "unprognostic (9.80e-2)" RFX5 ENSG00000143390 "Regulatory factor X5" P48382 1 151340640-151347326 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018519, HPA079241" Supported Supported Nucleoplasm,Vesicles NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 82: Dendritic cells - Antigen presentation" 13 Nucleoplasm Vesicles "HPA018519: , HPA079241: " "unprognostic (1.40e-2)" "unprognostic (8.17e-2)" "unprognostic (1.72e-2)" "unprognostic (5.52e-2)" "unprognostic (3.49e-1)" "unprognostic (2.24e-2)" "unprognostic (7.79e-2)" "potential prognostic favorable (8.01e-4)" "unprognostic (3.67e-2)" "unprognostic (1.33e-2)" "unprognostic (2.00e-2)" "unprognostic (1.90e-1)" "unprognostic (1.55e-1)" "unprognostic (4.02e-2)" "unprognostic (4.49e-1)" "unprognostic (4.64e-2)" "unprognostic (2.77e-1)" "unprognostic (6.32e-2)" "unprognostic (4.24e-2)" "unprognostic (1.28e-1)" "unprognostic (3.81e-1)" "unprognostic (1.31e-1)" "unprognostic (4.15e-1)" "unprognostic (1.08e-1)" "unprognostic (1.16e-1)" "unprognostic (3.58e-2)" "unprognostic (8.06e-2)" "unprognostic (2.26e-3)" "unprognostic (1.41e-1)" "unprognostic (2.12e-1)" "unprognostic (1.81e-1)" RFX6 "dJ955L16.1, MGC33442, RFXDC1" ENSG00000185002 "Regulatory factor X6" Q8HWS3 6 116877212-116932161 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adrenal gland: 4.3;intestine: 2.1;pancreas: 2.2;stomach 1: 6.1" "Group enriched" "Detected in some" 8 "Adrenal medulla cells: 170.2;Neuroendocrine cells: 262.3;Pancreatic islet cells: 306.7" "Cell type enhanced" "Detected in single" "hippocampal CA1-3: 1.2" "Cancer enhanced" "Detected in single" "Pancreatic Adenocarcinoma (TCGA): 2.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 1.7;lung cancer: 1.0" "Adrenal gland - Adrenal medulla cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Minor Salivary Gland - Minor salivary gland ductal cells, Pancreas - Alpha cells, Pancreas - Beta cells, Pituitary gland - Somatotropes, Stomach - Gastric enteroendocrine cells, Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" HPA037696 Approved NA NA "Cluster 60: Stomach - Digestion" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" 26 "HPA037696: " "unprognostic (3.93e-1)" "potential prognostic favorable (6.00e-5)" "unprognostic (7.95e-2)" RFX7 "FLJ12994, RFXDC2" ENSG00000181827 "Regulatory factor X7" Q2KHR2 15 56087280-56245082 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Autism spectrum disorder, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Megakaryocyte-Erythroid progenitors: 466.3;Myonuclei: 638.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035462, HPA057957" Approved Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 58: Non-specific - Nuclear processes" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 11 "Nucleoplasm, Nuclear membrane" "HPA035462: , HPA057957: " "unprognostic (1.25e-2)" "unprognostic (1.93e-1)" "unprognostic (2.55e-1)" "unprognostic (5.15e-2)" "unprognostic (1.65e-1)" "unprognostic (1.41e-1)" "unprognostic (7.94e-2)" "unprognostic (1.34e-2)" "unprognostic (4.96e-2)" "unprognostic (3.96e-3)" "potential prognostic favorable (6.19e-4)" "unprognostic (2.22e-1)" "unprognostic (8.58e-3)" "unprognostic (7.66e-2)" "unprognostic (1.77e-1)" "unprognostic (1.17e-1)" "unprognostic (2.81e-2)" "unprognostic (1.87e-1)" "unprognostic (4.86e-3)" "unprognostic (3.17e-2)" "unprognostic (1.52e-1)" "unprognostic (2.01e-2)" "unprognostic (1.01e-1)" "unprognostic (2.12e-1)" "unprognostic (5.79e-2)" "unprognostic (3.66e-2)" "unprognostic (2.38e-2)" "unprognostic (9.60e-2)" "unprognostic (2.45e-1)" "unprognostic (3.77e-2)" "unprognostic (1.44e-1)" RFX8 FLJ42986 ENSG00000196460 "Regulatory factor X8" Q6ZV50 2 101397359-101475112 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "bone marrow: 3.5" "Cell type enhanced" "Detected in many" "Early spermatids: 19.2;Ependymal cells: 18.1;Fibro-adipogenic progenitors: 30.4;Fibroblasts: 15.3;Hematopoietic stem cells: 19.4;Late primary spermatocytes: 16.2;Late spermatids: 23.7;Mesothelial cells: 48.7;Monocyte progenitors: 34.4;Neutrophil progenitors: 18.1;Retinal ganglion cells: 38.6;Thymocytes: 43.2" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 5.5;Sarcoma: 3.9;thyroid cancer: 3.7" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Mesothelial cells, Breast - Fibroblasts, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA059745 Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 44: Bone marrow - Nuclear processes" "Cluster 53: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" Nucleoplasm "Nuclear bodies" "HPA059745: " "unprognostic (2.18e-1)" "unprognostic (1.77e-2)" "unprognostic (3.75e-2)" "unprognostic (2.13e-1)" "unprognostic (1.70e-3)" RFXANK "ANKRA1, BLS, F14150_1, MGC138628, RFX-B" ENSG00000064490 "Regulatory factor X associated ankyrin containing protein" O14593 19 19192229-19201869 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 112.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049157, HPA053330" Approved Enhanced Nucleoplasm NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 76 Nucleoplasm "HPA049157: , HPA053330: " "unprognostic (3.51e-1)" "unprognostic (9.05e-2)" "unprognostic (1.60e-1)" "unprognostic (5.71e-2)" "unprognostic (1.40e-1)" "unprognostic (1.27e-1)" "unprognostic (6.97e-2)" "unprognostic (5.74e-2)" "unprognostic (5.94e-2)" "unprognostic (3.42e-3)" "unprognostic (1.19e-3)" "unprognostic (2.05e-1)" "unprognostic (6.12e-2)" "unprognostic (2.28e-3)" "unprognostic (1.61e-3)" "unprognostic (3.18e-1)" "unprognostic (2.62e-3)" "unprognostic (1.49e-1)" "unprognostic (1.26e-1)" "unprognostic (5.25e-2)" "unprognostic (1.45e-1)" "unprognostic (1.73e-2)" "unprognostic (6.64e-2)" "unprognostic (1.22e-1)" "unprognostic (1.78e-1)" "unprognostic (2.56e-1)" "unprognostic (1.27e-1)" "unprognostic (1.56e-2)" "unprognostic (9.50e-2)" "unprognostic (2.73e-2)" "unprognostic (1.09e-1)" RFXAP ENSG00000133111 "Regulatory factor X associated protein" O00287 13 36819222-36829104 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" DNA-binding "Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" HPA032035 Supported "Nuclear speckles" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 2: Neurons - Nucleosome" "Cluster 19: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 8 "Nuclear speckles" "HPA032035: " "unprognostic (6.53e-2)" "unprognostic (1.65e-1)" "unprognostic (1.95e-1)" "unprognostic (2.10e-1)" "unprognostic (2.84e-1)" "unprognostic (3.49e-1)" "unprognostic (3.56e-2)" "unprognostic (1.92e-1)" "potential prognostic unfavorable (9.50e-4)" "unprognostic (4.96e-2)" "potential prognostic favorable (3.48e-4)" "unprognostic (6.36e-3)" "unprognostic (1.23e-3)" "unprognostic (4.88e-2)" "potential prognostic favorable (8.39e-5)" "unprognostic (8.71e-2)" "unprognostic (1.42e-1)" "unprognostic (1.16e-2)" "unprognostic (2.44e-2)" "potential prognostic unfavorable (1.48e-5)" "unprognostic (2.30e-3)" "unprognostic (6.76e-2)" "unprognostic (2.09e-1)" "potential prognostic favorable (1.69e-4)" "unprognostic (1.63e-3)" "unprognostic (7.00e-2)" "unprognostic (1.97e-3)" "unprognostic (2.15e-1)" "unprognostic (1.46e-1)" "unprognostic (1.88e-2)" RGCC "bA157L14.2, C13orf15, RGC-32, RGC32" ENSG00000102760 "Regulator of cell cycle" Q9H4X1 13 41457550-41470871 "Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 391.7;lung: 668.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 384.3;Bergmann glia: 482.7;Breast lactating cells: 544.0;Breast secretory cells: 542.6;cDC: 375.2;Fallopian tube ciliated cells: 330.4;Hofbauer cells: 374.1;Innate lymphoid cells: 333.5;Late primary spermatocytes: 342.1;Neutrophil progenitors: 439.7;Schwann cells: 509.0;T-cells: 437.0;Vascular endothelial cells: 439.0" "Cell type enhanced" "Detected in many" "Bergmann glia: 596.0;endothelial cell: 312.4;oligodendrocyte: 207.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 160.9;T-reg: 91.1" "Lineage enriched" "Detected in many" 15 "T-cells: 160.9" "Cancer enhanced" "Detected in many" "lymphoma: 34.0" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035638, HPA063701" Enhanced Supported Nucleoplasm,Nucleoli No No 870000 "Cluster 31: T-cells - T-cell receptor" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 3 Nucleoplasm Nucleoli "HPA035638: , HPA063701: " "unprognostic (1.08e-1)" "unprognostic (5.66e-3)" "unprognostic (1.65e-1)" "unprognostic (1.37e-2)" "unprognostic (1.10e-1)" "unprognostic (6.05e-2)" "unprognostic (6.16e-2)" "unprognostic (2.75e-1)" "unprognostic (2.41e-1)" "validated prognostic favorable (3.81e-11)" "validated prognostic favorable (3.68e-4)" "unprognostic (2.50e-1)" "potential prognostic favorable (5.37e-4)" "unprognostic (2.73e-3)" "unprognostic (3.25e-2)" "unprognostic (1.33e-3)" "unprognostic (1.89e-1)" "potential prognostic unfavorable (4.69e-4)" "unprognostic (3.08e-2)" "unprognostic (1.15e-1)" "unprognostic (2.47e-1)" "unprognostic (1.70e-1)" "unprognostic (1.82e-2)" "unprognostic (2.35e-2)" "unprognostic (3.73e-2)" "unprognostic (7.08e-3)" "unprognostic (2.46e-1)" "unprognostic (2.09e-1)" "unprognostic (9.80e-2)" RGL1 RGL ENSG00000143344 "Ral guanine nucleotide dissociation stimulator like 1" Q9NZL6 1 183636085-183928532 "Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bergmann glia: 280.4;Choroid plexus epithelial cells: 424.6;Hofbauer cells: 254.4;Kupffer cells: 522.7;Macrophages: 455.9;Pituicytes/FSCs: 350.9;Proximal tubule cells: 255.8;Retinal pigment epithelial cells: 264.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "intermediate monocyte: 2.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Prostate - Fibroblasts, Spleen - Macrophages, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019788 Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 38: Sub-cortical - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 4 "Nucleoplasm, Golgi apparatus, Vesicles" "HPA019788: " "unprognostic (2.26e-2)" "unprognostic (3.46e-1)" "unprognostic (8.83e-3)" "unprognostic (6.62e-2)" "unprognostic (6.72e-2)" "unprognostic (7.05e-2)" "unprognostic (4.65e-1)" "unprognostic (1.76e-1)" "unprognostic (4.52e-3)" "unprognostic (9.70e-2)" "potential prognostic favorable (3.26e-8)" "unprognostic (2.49e-3)" "potential prognostic favorable (8.64e-4)" "potential prognostic unfavorable (8.28e-5)" "unprognostic (1.27e-2)" "unprognostic (4.57e-3)" "unprognostic (2.79e-1)" "unprognostic (4.04e-2)" "unprognostic (3.63e-2)" "unprognostic (2.97e-2)" "unprognostic (2.46e-2)" "potential prognostic favorable (9.91e-4)" "unprognostic (5.28e-2)" "unprognostic (4.95e-2)" "unprognostic (1.37e-1)" "potential prognostic favorable (6.21e-4)" "unprognostic (2.27e-2)" "unprognostic (1.48e-2)" "unprognostic (5.99e-2)" "unprognostic (2.24e-2)" "unprognostic (1.38e-1)" RGL2 "HKE1.5, KE1.5, RAB2L" ENSG00000237441 "Ral guanine nucleotide dissociation stimulator like 2" O15211 6 33291654-33298942 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 64.9;Bergmann glia: 51.7;Brain inhibitory neurons: 23.3;Choroid plexus epithelial cells: 40.8;Ependymal cells: 57.7;Loop of henle epithelial cells: 20.8;Microglia: 48.0;Oligodendrocyte progenitor cells: 29.5;Papillary tip epithelial cells: 34.3;Podocytes: 19.9;Proximal tubule cells: 19.8;Renal collecting duct principal cells: 24.7;Renal connecting tubule cells: 16.6;Tuft cells: 23.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047039, HPA053444" Approved Approved Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 8: Immune cells - Immune response" "Cluster 72: Neuronal - Signal transduction" "Cluster 102: Non-specific - Mixed function" 10 Nucleoplasm "HPA047039: , HPA053444: " "unprognostic (1.24e-1)" "unprognostic (2.81e-1)" "unprognostic (9.55e-2)" "unprognostic (5.34e-2)" "unprognostic (5.49e-2)" "unprognostic (3.52e-2)" "unprognostic (4.10e-2)" "unprognostic (1.13e-1)" "unprognostic (1.72e-1)" "potential prognostic favorable (6.12e-9)" "unprognostic (9.41e-3)" "unprognostic (1.03e-2)" "unprognostic (3.61e-2)" "unprognostic (4.32e-1)" "unprognostic (5.20e-2)" "unprognostic (2.12e-1)" "validated prognostic unfavorable (8.42e-4)" "validated prognostic unfavorable (6.98e-5)" "unprognostic (1.01e-1)" "unprognostic (9.24e-2)" "unprognostic (1.07e-1)" "unprognostic (1.19e-3)" "unprognostic (7.60e-2)" "unprognostic (1.80e-1)" "unprognostic (6.09e-2)" "unprognostic (1.96e-2)" "unprognostic (1.31e-1)" "unprognostic (5.50e-2)" "unprognostic (3.64e-1)" RGL3 FLJ32585 ENSG00000205517 "Ral guanine nucleotide dissociation stimulator like 3" Q3MIN7 19 11384341-11419328 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 42.1;parathyroid gland: 43.1;thyroid gland: 61.9" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 237.0;Loop of henle epithelial cells: 182.6;Papillary tip epithelial cells: 109.1;Pericytes: 102.3;Renal collecting duct intercalated cells: 221.4;Renal collecting duct principal cells: 218.9;Renal connecting tubule cells: 220.1" "Cell type enhanced" "Detected in many" "astrocyte: 35.9;central nervous system macrophage: 46.1;choroid plexus epithelial cell: 52.0;pericyte: 42.1;vascular associated smooth muscle cell: 43.5" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 38.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skin - Endothelial cells" "Region enriched" "Detected in many" 6 "cerebellum: 9.0" "Low region specificity" "Detected in many" "HPA042763, HPA043615, HPA064578" Uncertain Approved Nucleoplasm NA NA "Cluster 33: Thyroid gland - Tissue development" "Cluster 8: Immune cells - Immune response" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 30 Nucleoplasm "HPA042763: , HPA043615: , HPA064578: " "unprognostic (1.27e-1)" "unprognostic (6.40e-3)" "unprognostic (3.82e-1)" "unprognostic (1.17e-1)" "unprognostic (1.41e-1)" "unprognostic (1.46e-2)" "unprognostic (1.89e-1)" "unprognostic (7.58e-2)" "unprognostic (9.22e-3)" "validated prognostic favorable (1.00e-5)" "validated prognostic favorable (4.61e-4)" "unprognostic (9.29e-2)" "unprognostic (3.74e-2)" "unprognostic (1.52e-1)" "unprognostic (1.01e-1)" "unprognostic (2.75e-1)" "unprognostic (2.63e-3)" "unprognostic (1.59e-1)" "unprognostic (1.22e-1)" "unprognostic (1.79e-1)" "unprognostic (1.33e-2)" "potential prognostic unfavorable (2.52e-4)" "unprognostic (2.23e-1)" "unprognostic (1.57e-1)" "unprognostic (2.65e-1)" "unprognostic (1.10e-1)" "unprognostic (4.20e-2)" "unprognostic (4.23e-1)" "unprognostic (2.65e-1)" "unprognostic (5.30e-2)" RGL4 Rgr ENSG00000159496 "Ral guanine nucleotide dissociation stimulator like 4" Q8IZJ4 22 23688136-23699176 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 8 "bone marrow: 149.8" "Group enriched" "Detected in many" 5 "Neutrophil progenitors: 327.0;Neutrophils: 236.8" "Cell type enhanced" "Detected in some" "leukocyte: 9.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 394.7;neutrophil: 519.0" "Lineage enriched" "Detected in all" 5 "granulocytes: 519.0" "Cancer enhanced" "Detected in many" "Leukemia: 12.6" "Lung - Neutrophils_2, Prostate - T-cells, Spleen - Neutrophils_2, Testis - Early spermatids, Testis - Late spermatids" HPA035979 Uncertain Approved Centrosome "Intracellular and membrane" Other NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 1 Centrosome "HPA035979: " "unprognostic (7.07e-3)" "unprognostic (1.78e-3)" "unprognostic (1.27e-2)" "potential prognostic favorable (5.68e-4)" "unprognostic (2.78e-1)" "unprognostic (1.72e-1)" "unprognostic (1.72e-2)" "potential prognostic favorable (2.46e-4)" "unprognostic (2.26e-1)" "unprognostic (2.54e-2)" "potential prognostic favorable (6.68e-4)" "unprognostic (1.23e-3)" "unprognostic (9.22e-2)" "potential prognostic favorable (6.22e-4)" "unprognostic (8.15e-2)" "unprognostic (8.66e-2)" "unprognostic (2.32e-3)" "unprognostic (7.91e-2)" "unprognostic (7.48e-2)" "unprognostic (1.87e-2)" "unprognostic (3.69e-3)" "unprognostic (4.29e-2)" "unprognostic (1.10e-1)" "unprognostic (2.78e-1)" "unprognostic (2.50e-1)" "unprognostic (8.29e-2)" RGMA RGM ENSG00000182175 "Repulsive guidance molecule BMP co-receptor a" Q96B86 15 93035271-93089211 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 189.3" "Cell type enhanced" "Detected in many" "Astrocytes: 288.7;Bergmann glia: 265.8;Ependymal cells: 110.8;Esophageal basal cells: 64.7;Fibro-adipogenic progenitors: 155.6;Leydig cells: 198.9;Myonuclei: 73.6;Myosatellite cells: 66.7;Peritubular myoid cells: 165.5" "Group enriched" "Detected in many" 4 "astrocyte: 412.6;Bergmann glia: 280.0;ependymal cell: 144.7" "Cancer enriched" "Detected in many" 7 "Glioblastoma Multiforme (TCGA): 177.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 12.3;Sarcoma: 10.4" "Adrenal gland - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblasts_2, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012343, HPA039880, HPA044222" Approved Approved Nucleoplasm,Cytosol "Secreted - unknown location" "No annotated function" NA NA 870000 "Cluster 25: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 28: Astrocytes - Homeostasis & neuron support" 1 Nucleoplasm Cytosol "CAB012343: , HPA039880: , HPA044222: " "unprognostic (8.08e-2)" "unprognostic (1.20e-2)" "unprognostic (1.00e-1)" "unprognostic (1.52e-1)" "unprognostic (2.51e-2)" "unprognostic (4.32e-2)" "unprognostic (2.79e-1)" "unprognostic (1.45e-1)" "unprognostic (3.02e-3)" "unprognostic (4.30e-2)" "unprognostic (1.56e-1)" "unprognostic (1.91e-3)" "unprognostic (3.54e-2)" "unprognostic (1.46e-2)" "unprognostic (3.26e-2)" "unprognostic (1.16e-3)" "unprognostic (1.08e-3)" "unprognostic (4.34e-2)" "unprognostic (1.43e-1)" "unprognostic (1.44e-1)" "unprognostic (8.41e-2)" "unprognostic (3.98e-2)" "unprognostic (3.13e-2)" "unprognostic (4.87e-3)" "unprognostic (6.27e-2)" "unprognostic (4.08e-2)" "unprognostic (1.49e-1)" "unprognostic (1.67e-1)" "unprognostic (6.99e-2)" RGMB "DRAGON, FLJ90406" ENSG00000174136 "Repulsive guidance molecule BMP co-receptor b" Q6NW40 5 98768650-98798643 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 115.4;Enteric stem cells: 265.7;Gastric chief cells: 117.9;Late spermatids: 91.7;Mucous neck cells: 119.7;Paneth cells: 286.2;Parietal cells: 150.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 3.3" "Group enriched" "Detected in many" 12 "B-cells: 1.6;T-cells: 3.3" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Smooth muscle cells, Skin - Keratinocyte (other), Spleen - Endothelial cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016993 Approved Nucleoplasm NA NA 110000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 77: Intestine - Digestion" "Cluster 1: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 2 Nucleoplasm "HPA016993: " "unprognostic (1.38e-3)" "unprognostic (8.16e-3)" "unprognostic (1.49e-1)" "unprognostic (2.29e-1)" "unprognostic (2.61e-2)" "unprognostic (3.46e-2)" "unprognostic (6.70e-2)" "unprognostic (7.19e-3)" "unprognostic (1.87e-1)" "unprognostic (1.28e-1)" "unprognostic (1.44e-3)" "unprognostic (3.54e-2)" "unprognostic (1.52e-1)" "unprognostic (7.41e-2)" "unprognostic (8.07e-2)" "unprognostic (1.79e-1)" "unprognostic (1.99e-2)" "unprognostic (3.27e-2)" "unprognostic (5.93e-2)" "unprognostic (4.57e-2)" "unprognostic (8.88e-3)" "unprognostic (1.68e-1)" "unprognostic (2.75e-1)" "unprognostic (4.63e-1)" "unprognostic (3.32e-2)" "unprognostic (2.12e-2)" "unprognostic (1.15e-1)" "unprognostic (2.36e-2)" "unprognostic (2.68e-1)" "unprognostic (9.99e-2)" "unprognostic (3.21e-1)" RGN "RC, SMP30" ENSG00000130988 Regucalcin Q15493 X 47078355-47093314 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "adrenal gland: 176.1;liver: 358.7" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 834.3;Epididymal efferent duct absorptive cells: 151.0;Epididymal efferent duct ciliated cells: 87.3;Hepatocytes: 280.0;Peritubular myoid cells: 104.4;Proximal tubule cells: 142.6;Retinal pigment epithelial cells: 106.6" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 77.2" "Cancer enriched" "Detected in many" 5 "Liver Hepatocellular Carcinoma (TCGA): 93.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "liver cancer: 11.0" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Pituitary gland - Undifferentiated cells (Pituitary gland), Skeletal muscle - Skeletal myocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA029102, HPA029103, HPA029104" Enhanced Approved Cytosol NA NA 730000 "Cluster 76: Non-specific - Metabolism" "Cluster 25: Non-specific - Transcription" "Cluster 18: Liver cancer - Metabolism" "Cluster 18: Adrenal cortex cells - Steroidogensis" Cytosol "HPA029102: , HPA029103: , HPA029104: " "unprognostic (1.18e-1)" "unprognostic (1.34e-1)" "unprognostic (8.04e-3)" "unprognostic (1.89e-2)" "unprognostic (1.12e-1)" "unprognostic (4.42e-3)" "potential prognostic unfavorable (4.61e-4)" "unprognostic (3.54e-3)" "potential prognostic favorable (4.64e-6)" "unprognostic (5.02e-3)" "potential prognostic favorable (1.44e-4)" "unprognostic (1.11e-3)" "potential prognostic favorable (2.55e-4)" "potential prognostic favorable (1.96e-5)" "unprognostic (2.09e-2)" "unprognostic (9.91e-3)" "unprognostic (1.57e-1)" "unprognostic (1.48e-1)" "unprognostic (1.76e-1)" "unprognostic (2.68e-2)" "unprognostic (8.58e-2)" "unprognostic (2.42e-2)" "unprognostic (1.03e-1)" "unprognostic (2.41e-1)" "unprognostic (1.41e-2)" "unprognostic (2.18e-1)" "unprognostic (3.87e-2)" "unprognostic (2.21e-2)" RGP1 KIAA0258 ENSG00000107185 "RGP1 homolog, RAB6A GEF complex partner 1" Q92546 9 35749287-35758585 "Essential proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020414, HPA021085" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 32: Basophils - Transcription" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 7 Cytosol "Plasma membrane" "HPA020414: , HPA021085: " "unprognostic (6.11e-2)" "unprognostic (1.69e-1)" "unprognostic (1.72e-1)" "unprognostic (2.61e-3)" "unprognostic (1.91e-1)" "unprognostic (2.16e-1)" "unprognostic (1.38e-1)" "unprognostic (4.81e-2)" "unprognostic (3.98e-2)" "unprognostic (4.80e-2)" "validated prognostic favorable (2.53e-10)" "validated prognostic favorable (6.16e-4)" "potential prognostic favorable (6.35e-5)" "unprognostic (2.91e-3)" "unprognostic (6.35e-2)" "unprognostic (2.34e-1)" "unprognostic (3.06e-2)" "unprognostic (8.79e-2)" "unprognostic (1.66e-1)" "unprognostic (3.02e-2)" "unprognostic (2.58e-1)" "unprognostic (4.72e-3)" "unprognostic (4.52e-2)" "unprognostic (1.54e-1)" "unprognostic (1.00e-1)" "unprognostic (3.78e-2)" "unprognostic (1.85e-1)" "unprognostic (1.55e-1)" "unprognostic (3.03e-1)" "unprognostic (4.89e-3)" "unprognostic (1.10e-1)" RGPD1 RGP1 ENSG00000187627 "RANBP2 like and GRIP domain containing 1" 2 86913783-87013976 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 4 "cervix: 8.0;placenta: 9.2;testis: 22.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 41.8;Cytotrophoblasts: 47.5;Early primary spermatocytes: 16.4;Early spermatids: 32.7;Extravillous trophoblasts: 52.4;Migrating cytotrophoblasts: 26.5;Syncytiotrophoblasts: 55.9" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 11 "testis cancer: 11.2" "Pituitary gland - Corticotropes" "HPA049497, HPA051675, HPA067564" Uncertain Approved "Nuclear membrane,Vesicles" NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 49: Hindbrain - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 6 "Nuclear membrane, Vesicles" "HPA049497: , HPA051675: , HPA067564: " "unprognostic (1.83e-1)" "unprognostic (2.80e-2)" "unprognostic (1.71e-1)" "unprognostic (2.26e-2)" RGPD2 "RANBP2L2, RGP2" ENSG00000185304 "RANBP2 like and GRIP domain containing 2" P0DJD1 2 87755960-87825796 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 13.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 21.9;Epicardial cells: 22.7;Extravillous trophoblasts: 32.3;Lactotrophs: 19.4;Pancreatic acinar cells: 38.9;pDCs: 22.0;Plasma cells: 20.2;Syncytiotrophoblasts: 57.1;T-cells: 21.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "T-reg: 9.8" "Lineage enriched" "Detected in single" 26 "T-cells: 9.8" "Cancer enhanced" "Detected in many" "testis cancer: 7.5" "HPA049497, HPA051675, HPA067564" Uncertain Approved "Nuclear membrane,Vesicles" NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 47: Testis - Mixed function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" 1 "Nuclear membrane, Vesicles" "HPA049497: , HPA051675: , HPA067564: " "unprognostic (2.36e-2)" "unprognostic (1.09e-1)" "unprognostic (2.54e-1)" "unprognostic (9.66e-2)" "unprognostic (4.23e-2)" "unprognostic (3.00e-3)" "unprognostic (2.75e-1)" "unprognostic (1.13e-2)" "unprognostic (3.61e-1)" RGPD3 RGP3 ENSG00000153165 "RANBP2 like and GRIP domain containing 3" A6NKT7 2 106391290-106468413 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 5.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 7.8;Early primary spermatocytes: 8.5;Early spermatids: 43.8;Epicardial cells: 13.6;Hepatocytes: 15.9;Late primary spermatocytes: 23.7;Retinal bipolar cells: 9.0;Thymocytes: 9.3" "Group enriched" "Detected in many" 5 "choroid plexus epithelial cell: 16.1;endothelial cell: 13.0;lower rhombic lip: 6.7;midbrain-derived inhibitory: 11.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Leukemia: 2.4" "Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "HPA049497, HPA051675, HPA067564" Uncertain Approved "Nuclear membrane,Vesicles" NA NA "Cluster 67: Testis - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" 3 "Nuclear membrane, Vesicles" "HPA049497: , HPA051675: , HPA067564: " "unprognostic (9.48e-3)" "unprognostic (1.03e-3)" RGPD4 "DKFZp686P0288, RGP4" ENSG00000196862 "RANBP2 like and GRIP domain containing 4" Q7Z3J3 2 107826892-107892544 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 2.9" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 10.6;Early primary spermatocytes: 5.8;Early spermatids: 20.5;Late primary spermatocytes: 17.1;Retinal bipolar cells: 8.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "HPA049497, HPA051675, HPA067564" Uncertain Approved "Nuclear membrane,Vesicles" NA NA "Cluster 67: Testis - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 4 "Nuclear membrane, Vesicles" "HPA049497: , HPA051675: , HPA067564: " "unprognostic (9.95e-2)" RGPD5 "BS-63, DKFZp686I1842, RGP5" ENSG00000015568 "RANBP2 like and GRIP domain containing 5" Q99666 2 109792758-109857705 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Astrocytes: 2.6;Bergmann glia: 3.5;Brain excitatory neurons: 4.3;Brain inhibitory neurons: 3.9;Choroid plexus epithelial cells: 1.6;Ependymal cells: 2.4;Microglia: 3.9;Oligodendrocyte progenitor cells: 3.5;Oligodendrocytes: 3.5;Other brain neurons: 3.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA045704, HPA049497, HPA051675, HPA067564" Uncertain Uncertain "Nuclear membrane,Vesicles" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 21: Testis - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" 28 "Nuclear membrane, Vesicles" "HPA045704: , HPA049497: , HPA051675: , HPA067564: " "unprognostic (4.15e-2)" "unprognostic (2.66e-2)" "unprognostic (3.09e-2)" "unprognostic (2.25e-2)" "unprognostic (2.36e-2)" "unprognostic (1.01e-1)" "unprognostic (9.94e-2)" "unprognostic (1.51e-1)" "unprognostic (2.54e-1)" "unprognostic (2.98e-1)" "unprognostic (1.97e-2)" "unprognostic (1.07e-2)" "unprognostic (1.61e-2)" "unprognostic (7.82e-3)" "unprognostic (8.04e-2)" "unprognostic (2.16e-2)" "unprognostic (5.08e-2)" "unprognostic (2.00e-3)" "unprognostic (1.26e-1)" "unprognostic (1.24e-1)" "unprognostic (2.64e-3)" "unprognostic (3.01e-3)" "unprognostic (1.96e-1)" "unprognostic (2.23e-1)" "unprognostic (7.29e-2)" "unprognostic (3.08e-1)" "unprognostic (2.60e-1)" "unprognostic (5.59e-2)" "unprognostic (3.10e-2)" RGPD6 RGP6 ENSG00000183054 "RANBP2 like and GRIP domain containing 6" Q99666 2 110513802-110610840 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 24.9" "Group enriched" "Detected in some" 4 "Gonadotrophs: 9.9;Lactotrophs: 18.6;Pituicytes/FSCs: 13.0;Somatotrophs: 17.5;Thyrotrophs: 13.7" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA045704, HPA049497, HPA051675, HPA067564" Uncertain Uncertain "Nuclear membrane,Vesicles" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 24 "Nuclear membrane, Vesicles" "HPA045704: , HPA049497: , HPA051675: , HPA067564: " "unprognostic (9.17e-3)" "unprognostic (1.22e-1)" "unprognostic (4.12e-3)" "unprognostic (2.19e-2)" "unprognostic (2.76e-1)" "unprognostic (4.31e-3)" "unprognostic (9.70e-2)" "unprognostic (9.26e-2)" "unprognostic (1.50e-1)" "unprognostic (2.84e-1)" "unprognostic (1.70e-3)" "unprognostic (2.11e-1)" "unprognostic (2.95e-2)" "unprognostic (2.47e-1)" "unprognostic (9.74e-2)" "unprognostic (8.80e-2)" "unprognostic (3.28e-1)" "unprognostic (5.88e-2)" "unprognostic (6.38e-2)" "unprognostic (9.99e-2)" "unprognostic (1.70e-3)" "unprognostic (8.17e-2)" "unprognostic (2.46e-2)" "unprognostic (1.94e-1)" "unprognostic (1.56e-2)" "unprognostic (3.96e-1)" "unprognostic (3.38e-2)" "unprognostic (5.94e-2)" RGPD8 "RanBP2alpha, RANBP2L1" ENSG00000169629 "RANBP2 like and GRIP domain containing 8" O14715 2 112368369-112434488 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 50.6;Lactotrophs: 40.9;Somatotrophs: 34.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "HPA045704, HPA049497, HPA051675, HPA067564" Uncertain Approved "Nuclear membrane,Vesicles" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 17 "Nuclear membrane, Vesicles" "HPA045704: , HPA049497: , HPA051675: , HPA067564: " "unprognostic (6.27e-3)" "unprognostic (1.02e-1)" "unprognostic (4.31e-2)" "unprognostic (1.51e-1)" "unprognostic (1.56e-1)" "unprognostic (2.71e-1)" "unprognostic (7.31e-2)" "unprognostic (1.13e-1)" "unprognostic (5.13e-2)" "unprognostic (4.34e-3)" "unprognostic (1.09e-1)" "unprognostic (2.65e-2)" "unprognostic (2.46e-2)" "unprognostic (1.49e-1)" "unprognostic (1.57e-1)" "unprognostic (2.66e-3)" "unprognostic (1.67e-2)" "unprognostic (2.33e-1)" "potential prognostic unfavorable (4.65e-5)" "unprognostic (8.17e-2)" "unprognostic (2.32e-1)" "unprognostic (1.61e-1)" "unprognostic (1.84e-1)" "unprognostic (4.53e-2)" "unprognostic (7.55e-2)" "unprognostic (1.10e-2)" RGR RP44 ENSG00000148604 "Retinal G protein coupled receptor" P47804 10 84230666-84259960 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Sensory transduction, Vision" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "choroid plexus: 32.4;retina: 129.0" "Group enriched" "Detected in some" 28 "Müller glia: 1640.1;Retinal pigment epithelial cells: 2638.8" "Group enriched" "Detected in some" 11 "astrocyte: 22.7;Bergmann glia: 13.0;choroid plexus epithelial cell: 8.1;committed oligodendrocyte precursor: 27.1;oligodendrocyte precursor cell: 7.2" "Cancer enriched" "Detected in single" 4 "Glioblastoma Multiforme (TCGA): 3.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "breast cancer: 1.2" "Prostate - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "midbrain: 25.5;olfactory bulb: 55.9;thalamus: 29.6" HPA059149 Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 27: Breast cancer - Unknown function" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" 3 Vesicles "Plasma membrane, Cytosol" "HPA059149: " "unprognostic (4.02e-2)" "unprognostic (1.57e-1)" "unprognostic (4.79e-3)" "unprognostic (8.65e-2)" RGS1 "1R20, BL34, IER1, IR20" ENSG00000090104 "Regulator of G protein signaling 1" Q08116 1 192575763-192580024 "Predicted intracellular proteins" "GTPase activation, Signal transduction inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 415.3" "Cell type enhanced" "Detected in many" "B-cells: 284.2;cDC: 611.7;Innate lymphoid cells: 350.9;Kupffer cells: 250.1;Macrophages: 789.5;Mast cells: 1605.9;NK-cells: 433.4;pDCs: 548.5;Plasma cells: 439.5;T-cells: 775.6" "Cell type enriched" "Detected in some" 5 "central nervous system macrophage: 235.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "eosinophil: 25.8;T-reg: 21.9" "Group enriched" "Detected in many" 5 "granulocytes: 25.8;T-cells: 21.9" "Cancer enhanced" "Detected in some" "lymphoma: 106.4;Myeloma: 117.1" "Adipose visceral - T-cells, Kidney - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Region enhanced" "Detected in all" "spinal cord: 101.2" HPA074572 Approved NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 9: T-cells - Adaptive immunity: Regulation" "HPA074572: " "unprognostic (1.14e-3)" "unprognostic (9.64e-3)" "unprognostic (2.38e-1)" "unprognostic (2.64e-2)" "unprognostic (1.51e-1)" "unprognostic (8.32e-2)" "unprognostic (2.77e-1)" "unprognostic (8.12e-2)" "unprognostic (8.54e-3)" "unprognostic (3.91e-1)" "unprognostic (1.10e-1)" "unprognostic (6.25e-2)" "unprognostic (2.60e-1)" "unprognostic (5.62e-2)" "unprognostic (2.46e-2)" "unprognostic (3.79e-2)" "unprognostic (2.91e-1)" "unprognostic (1.45e-1)" "unprognostic (1.28e-1)" "unprognostic (4.27e-2)" "unprognostic (4.43e-1)" "unprognostic (2.22e-2)" "unprognostic (6.84e-2)" "unprognostic (4.81e-1)" "unprognostic (2.33e-1)" "potential prognostic favorable (8.11e-7)" "unprognostic (4.83e-1)" "unprognostic (1.81e-3)" "unprognostic (4.88e-2)" "unprognostic (2.32e-2)" "unprognostic (2.68e-1)" RGS10 ENSG00000148908 "Regulator of G protein signaling 10" O43665 10 119499817-119542719 "Predicted intracellular proteins" "GTPase activation, Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 207.4" "Cell type enhanced" "Detected in many" "cDC: 404.6;Esophageal apical cells: 462.9;Hofbauer cells: 876.2;Megakaryocytes: 1551.6;Microglia: 334.6;Platelets: 4189.4" "Cell type enriched" "Detected in many" 8 "central nervous system macrophage: 404.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Macrophages, Heart muscle - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004559, HPA021305" Enhanced Supported Supported "Nucleoplasm,Nuclear bodies" NA NA 2000000 "Cluster 33: Non-specific - ATP binding" "Cluster 80: Thymus - Adaptive immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 47: Platelets - Hemostasis" 3 Nucleoplasm "Nuclear bodies" "CAB004559: , HPA021305: " "unprognostic (2.04e-1)" "unprognostic (9.48e-2)" "unprognostic (6.05e-3)" "unprognostic (2.99e-2)" "unprognostic (1.53e-2)" "unprognostic (4.06e-2)" "unprognostic (1.47e-1)" "unprognostic (5.15e-2)" "unprognostic (2.06e-2)" "unprognostic (1.24e-1)" "unprognostic (3.33e-3)" "unprognostic (1.25e-1)" "unprognostic (9.41e-2)" "unprognostic (1.44e-3)" "unprognostic (2.44e-1)" "unprognostic (2.85e-1)" "potential prognostic unfavorable (6.62e-5)" "unprognostic (6.30e-2)" "unprognostic (2.10e-2)" "unprognostic (2.40e-2)" "unprognostic (8.60e-2)" "unprognostic (4.55e-3)" "unprognostic (6.51e-2)" "unprognostic (2.59e-1)" "unprognostic (1.09e-1)" "unprognostic (9.00e-2)" "potential prognostic favorable (2.12e-4)" "unprognostic (2.93e-1)" "unprognostic (1.08e-1)" "unprognostic (9.63e-2)" "unprognostic (1.76e-2)" RGS11 ENSG00000076344 "Regulator of G protein signaling 11" O94810 16 268301-275980 "Predicted intracellular proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 164.0;pituitary gland: 52.6" "Cell type enhanced" "Detected in many" "Astrocytes: 40.1;Bergmann glia: 52.4;Brain excitatory neurons: 43.7;Brain inhibitory neurons: 36.3;Cone photoreceptor cells: 49.7;Corticotrophs: 26.5;Gonadotrophs: 68.3;Oligodendrocytes: 27.8;Other brain neurons: 45.3;Retinal bipolar cells: 42.3;Retinal ganglion cells: 81.1;Rod photoreceptor cells: 32.5" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 8.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 4.1" "Colon - Enteric glia cells, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA041692, HPA043039" Uncertain NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 37: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 2 "HPA041692: , HPA043039: " "unprognostic (2.87e-1)" "unprognostic (1.03e-1)" "unprognostic (6.80e-2)" "potential prognostic unfavorable (8.64e-4)" "unprognostic (8.85e-2)" "unprognostic (3.63e-2)" "potential prognostic favorable (7.47e-5)" "potential prognostic favorable (4.41e-4)" "unprognostic (2.72e-2)" "unprognostic (1.79e-2)" "unprognostic (1.84e-3)" "unprognostic (1.12e-3)" "unprognostic (1.01e-1)" "unprognostic (2.14e-1)" "unprognostic (2.82e-1)" "unprognostic (5.55e-2)" "unprognostic (7.57e-2)" "unprognostic (2.74e-1)" RGS12 ENSG00000159788 "Regulator of G protein signaling 12" O14924 4 3293021-3439913 "Plasma proteins, Predicted intracellular proteins" Transcription "GTPase activation, Repressor, Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epididymal basal cells: 494.6;Esophageal apical cells: 288.2;Esophageal suprabasal cells: 339.1;Ocular epithelial cells: 545.7;Suprabasal keratinocytes: 337.9" "Cell type enhanced" "Detected in all" "CGE interneuron: 657.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054646, HPA067421" Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 2: Non-specific - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 100: Stratified epithelial cells - Barrier functions" 9 "Nucleoplasm, Nucleoli" Cytosol "HPA054646: , HPA067421: " "unprognostic (2.99e-1)" "unprognostic (2.15e-1)" "unprognostic (2.13e-1)" "unprognostic (2.36e-1)" "unprognostic (1.97e-2)" "unprognostic (1.06e-2)" "unprognostic (1.99e-1)" "unprognostic (6.53e-3)" "unprognostic (2.84e-3)" "unprognostic (9.15e-2)" "validated prognostic favorable (2.62e-5)" "validated prognostic favorable (7.97e-4)" "potential prognostic favorable (1.63e-6)" "unprognostic (9.85e-2)" "unprognostic (3.24e-2)" "unprognostic (3.92e-3)" "unprognostic (3.41e-1)" "unprognostic (1.07e-1)" "unprognostic (2.82e-1)" "unprognostic (1.45e-1)" "unprognostic (1.25e-2)" "unprognostic (3.46e-2)" "unprognostic (5.20e-2)" "unprognostic (1.67e-1)" "unprognostic (1.48e-2)" "unprognostic (2.26e-2)" "unprognostic (2.21e-1)" "unprognostic (2.17e-2)" "unprognostic (1.75e-1)" "unprognostic (2.62e-2)" "unprognostic (7.07e-2)" RGS13 ENSG00000127074 "Regulator of G protein signaling 13" O14921 1 192636138-192660311 "Predicted intracellular proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "lymphoid tissue: 44.7" "Group enriched" "Detected in some" 4 "Mast cells: 595.2;Tuft cells: 587.9" "Cell type enhanced" "Detected in single" "midbrain-derived inhibitory: 2.2" "Cancer enhanced" "Detected in some" "Stomach Adenocarcinoma (TCGA): 1.9" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 39 "basophil: 6.9" "Lineage enriched" "Detected in single" 39 "granulocytes: 6.9" "Cancer enriched" "Detected in some" 13 "lymphoma: 62.9" "Adipose subcutaneous - Mast cells, Adipose visceral - Mast cells, Colon - Mast cells, Lung - Mast cells, Minor Salivary Gland - Mast cells, Skin - Mast cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA076656 Enhanced NA NA "Cluster 32: Basophils - Transcription" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 58: Mast cells - Allergic inflammatory responses" 1 "HPA076656: " "unprognostic (1.70e-2)" "unprognostic (3.69e-1)" "unprognostic (4.75e-1)" "unprognostic (2.44e-1)" "unprognostic (3.88e-1)" RGS14 ENSG00000169220 "Regulator of G protein signaling 14" O43566 5 177357924-177372596 "Predicted intracellular proteins" "Cell cycle, Cell division" "GTPase activation, Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 239.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 60.3;Esophageal apical cells: 113.1;Esophageal basal cells: 147.8;Esophageal suprabasal cells: 231.2;Hepatocytes: 73.2;Neutrophils: 123.0;Oocytes: 133.5;Suprabasal keratinocytes: 100.0" "Cell type enhanced" "Detected in many" "leukocyte: 34.7;medium spiny neuron: 49.2" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basal ganglia: 238.3;cerebral cortex: 147.2;hippocampal formation: 120.1" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 10 "amygdala: 66.0;basal ganglia: 57.9;cerebral cortex: 46.8;hippocampal formation: 93.6;white matter: 23.9" "Region enhanced" "Detected in many" "basal ganglia: 135.1" "HPA046847, HPA061819" Approved Uncertain "Nucleoplasm,Vesicles,Plasma membrane" No No "Cluster 21: Neutrophils - Unknown function" "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 85: Squamous epithelial cells - Keratinization" 7 "Nucleoplasm, Plasma membrane" Vesicles "HPA046847: , HPA061819: " "unprognostic (1.22e-1)" "unprognostic (7.55e-3)" "unprognostic (2.48e-1)" "unprognostic (1.11e-1)" "unprognostic (6.44e-2)" "unprognostic (9.98e-2)" "potential prognostic unfavorable (3.97e-5)" "unprognostic (6.16e-3)" "unprognostic (2.80e-2)" "unprognostic (1.58e-1)" "unprognostic (9.92e-3)" "unprognostic (2.23e-1)" "unprognostic (5.12e-2)" "unprognostic (7.17e-3)" "unprognostic (3.00e-1)" "unprognostic (5.14e-3)" "unprognostic (7.03e-2)" "unprognostic (7.23e-2)" "unprognostic (3.73e-1)" "unprognostic (4.27e-1)" "unprognostic (9.09e-2)" "unprognostic (1.09e-1)" "potential prognostic unfavorable (1.60e-4)" "unprognostic (3.77e-2)" "unprognostic (1.56e-1)" "unprognostic (2.15e-2)" "unprognostic (5.47e-3)" "unprognostic (2.86e-2)" "unprognostic (1.54e-1)" "unprognostic (1.02e-3)" "unprognostic (4.36e-2)" RGS16 "A28-RGS14, RGS-r" ENSG00000143333 "Regulator of G protein signaling 16" O15492 1 182598623-182604389 "Predicted intracellular proteins" "GTPase activation, Signal transduction inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 97.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 206.8;Decidual stromal cells: 270.1;Extravillous trophoblasts: 276.3;Lymphatic endothelial cells: 217.4;Müller glia: 252.0;Pericytes: 498.4;Retinal bipolar cells: 357.5;Schwann cells: 157.0;Smooth muscle cells: 179.7;Transitional alveolar cells: 154.6;Vascular smooth muscle cells: 398.0" "Cell type enriched" "Detected in many" 4 "thalamic excitatory: 165.1" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in all" 4 "hypothalamus: 94.6;midbrain: 144.7;thalamus: 275.6" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 9.7" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "lymphoma: 73.1;Myeloma: 64.5" "Stomach - Fibroblasts" "Region enriched" "Detected in all" 5 "thalamus: 79.9" "Group enriched" "Detected in many" 7 "midbrain: 99.9;pons: 88.0;thalamus: 160.1" "HPA053250, HPA055824" Uncertain Approved Cytosol NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 103: Non-specific - Basic cellular processes" 4 Cytosol "HPA053250: , HPA055824: " "unprognostic (3.05e-1)" "unprognostic (2.84e-2)" "unprognostic (8.62e-2)" "potential prognostic unfavorable (3.25e-4)" "unprognostic (5.58e-2)" "unprognostic (2.80e-2)" "unprognostic (1.43e-2)" "unprognostic (4.89e-2)" "unprognostic (1.66e-2)" "unprognostic (1.60e-1)" "unprognostic (1.58e-2)" "potential prognostic favorable (5.71e-4)" "unprognostic (3.11e-2)" "unprognostic (2.18e-2)" "potential prognostic favorable (5.15e-4)" "unprognostic (1.82e-1)" "unprognostic (3.03e-2)" "unprognostic (1.40e-2)" "unprognostic (1.99e-1)" "unprognostic (1.80e-2)" "unprognostic (8.46e-2)" "unprognostic (2.68e-2)" "unprognostic (7.79e-2)" "unprognostic (5.75e-2)" "unprognostic (2.62e-2)" "potential prognostic favorable (4.53e-4)" "unprognostic (2.50e-1)" "unprognostic (1.26e-1)" "unprognostic (1.66e-1)" "unprognostic (7.48e-3)" "unprognostic (2.92e-1)" RGS17 "RGS-17, RGSZ2" ENSG00000091844 "Regulator of G protein signaling 17" Q9UGC6 6 153004459-153131282 "Predicted intracellular proteins" "GTPase activation, Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.0" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 96.2;Brain inhibitory neurons: 143.2;Esophageal apical cells: 147.9;Lactotrophs: 100.1;Mast cells: 91.7;Medullary thymic epithelial cells: 124.8;Neuroendocrine cells: 108.0;Oligodendrocyte progenitor cells: 111.4;Other brain neurons: 178.2;Pancreatic duct cells: 71.3;Pancreatic islet cells: 188.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022276, HPA056493" Approved Approved Vesicles NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 34 Vesicles "HPA022276: , HPA056493: " "unprognostic (2.34e-1)" "unprognostic (2.21e-1)" "unprognostic (1.93e-1)" "unprognostic (4.34e-2)" "unprognostic (3.13e-2)" "unprognostic (7.76e-3)" "unprognostic (2.50e-1)" "potential prognostic unfavorable (3.76e-4)" "unprognostic (5.96e-2)" "unprognostic (7.60e-2)" RGS18 RGS13 ENSG00000150681 "Regulator of G protein signaling 18" Q9NS28 1 192158462-192185815 "Predicted intracellular proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 12.5;lymphoid tissue: 24.0" "Group enriched" "Detected in some" 4 "Megakaryocytes: 2577.7;Platelets: 6662.3" "Cell type enriched" "Detected in some" 4 "central nervous system macrophage: 100.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 353.9" "Lineage enriched" "Detected in many" 4 "granulocytes: 353.9" "Cancer enriched" "Detected in some" 5 "Leukemia: 18.9" "Adrenal gland - Macrophages, Kidney - Macrophages, Lung - Neutrophils_2, Minor Salivary Gland - Macrophages, Prostate - Macrophages, Spleen - Neutrophils_2, Testis - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA028727, HPA045780" Uncertain Approved "Golgi apparatus" NA NA 190000 "Cluster 21: Neutrophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 39: Astrocytes - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 47: Platelets - Hemostasis" 1 "Golgi apparatus" "HPA028727: , HPA045780: " "unprognostic (3.08e-2)" "unprognostic (1.12e-1)" "unprognostic (2.46e-1)" "unprognostic (3.68e-1)" "unprognostic (7.38e-2)" "unprognostic (1.06e-3)" "unprognostic (6.34e-2)" "unprognostic (3.86e-1)" "unprognostic (2.03e-3)" "unprognostic (1.31e-3)" "unprognostic (1.61e-1)" "unprognostic (1.14e-1)" "unprognostic (1.35e-1)" "unprognostic (1.29e-1)" "unprognostic (2.27e-2)" "unprognostic (2.46e-1)" "unprognostic (2.82e-2)" "unprognostic (5.91e-3)" RGS19 "GAIP, RGSGAIP" ENSG00000171700 "Regulator of G protein signaling 19" P49795 20 64073181-64079988 "Predicted intracellular proteins" Autophagy "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 54.1;lymphoid tissue: 73.8" "Cell type enhanced" "Detected in many" "B-cells: 83.6;cDC: 87.3;Hofbauer cells: 160.5;Kupffer cells: 123.0;Macrophages: 81.3;Megakaryocytes: 111.3;Microglia: 63.1;Monocyte progenitors: 80.8;monocytes: 110.1;Neutrophil progenitors: 128.7;Neutrophils: 273.7;pDCs: 81.8" "Group enriched" "Detected in many" 6 "central nervous system macrophage: 74.2;leukocyte: 46.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Colon - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056384, HPA069984" Enhanced Supported "Nucleoli fibrillar center,Cell Junctions" NA NA 5200 "Cluster 25: Non-specific - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 15 "Cell Junctions" "Nucleoli fibrillar center" "HPA056384: , HPA069984: " "unprognostic (1.12e-1)" "unprognostic (2.07e-1)" "unprognostic (2.47e-1)" "unprognostic (5.96e-2)" "unprognostic (4.59e-2)" "unprognostic (2.13e-1)" "unprognostic (2.29e-2)" "unprognostic (3.18e-1)" "unprognostic (5.54e-2)" "unprognostic (1.65e-1)" "unprognostic (1.06e-3)" "unprognostic (1.19e-2)" "unprognostic (4.30e-2)" "potential prognostic unfavorable (6.12e-4)" "unprognostic (3.86e-1)" "unprognostic (3.24e-1)" "unprognostic (2.80e-1)" "unprognostic (5.62e-3)" "unprognostic (1.86e-1)" "unprognostic (1.92e-2)" "unprognostic (1.16e-1)" "unprognostic (2.25e-1)" "potential prognostic unfavorable (6.46e-4)" "unprognostic (3.04e-1)" "unprognostic (1.07e-3)" "unprognostic (5.18e-2)" "unprognostic (2.31e-1)" "unprognostic (4.07e-2)" "unprognostic (3.15e-3)" "unprognostic (1.53e-1)" "unprognostic (5.48e-3)" RGS2 G0S8 ENSG00000116741 "Regulator of G protein signaling 2" P41220 1 192809039-192812275 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Translation regulation" "GTPase activation, Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast secretory cells: 747.6;cDC: 607.0;Hofbauer cells: 519.3;Macrophages: 491.7;Mast cells: 1540.0;monocytes: 695.9;Neutrophils: 2604.6;Oocytes: 469.7;pDCs: 572.8;Smooth muscle cells: 602.5" "Cell type enhanced" "Detected in many" "endothelial cell: 55.6;leukocyte: 58.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 3275.4;neutrophil: 4390.8" "Lineage enriched" "Detected in all" 8 "granulocytes: 4390.8" "Cancer enhanced" "Detected in all" "prostate cancer: 96.6" "Adipose visceral - Neutrophils, Prostate - Smooth muscle cells, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013385 Supported Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 15: Bone marrow - Innate immune response" "Cluster 21: Non-specific - Metabolism" "Cluster 5: Rhabdoid - Unknown function" "Cluster 58: Mast cells - Allergic inflammatory responses" 43 Cytosol "HPA013385: " "unprognostic (1.33e-1)" "unprognostic (5.20e-3)" "unprognostic (1.21e-1)" "unprognostic (4.73e-2)" "unprognostic (3.07e-1)" "unprognostic (1.16e-1)" "unprognostic (1.71e-1)" "potential prognostic unfavorable (3.74e-5)" "unprognostic (1.68e-1)" "unprognostic (7.86e-2)" "potential prognostic unfavorable (3.73e-4)" "unprognostic (9.17e-2)" "unprognostic (1.68e-1)" "potential prognostic unfavorable (8.80e-4)" "unprognostic (3.61e-1)" "unprognostic (1.10e-2)" "unprognostic (1.85e-1)" "unprognostic (3.35e-1)" "unprognostic (9.69e-2)" "unprognostic (8.86e-3)" "unprognostic (3.93e-1)" "unprognostic (7.28e-2)" "unprognostic (2.07e-2)" "unprognostic (9.72e-2)" "unprognostic (5.91e-3)" "unprognostic (4.47e-2)" "unprognostic (1.23e-1)" "potential prognostic unfavorable (3.66e-5)" "unprognostic (1.24e-1)" "unprognostic (1.42e-3)" "unprognostic (3.25e-2)" RGS20 "RGSZ1, ZGAP1" ENSG00000147509 "Regulator of G protein signaling 20" O76081 8 53851795-53959303 "Plasma proteins, Predicted intracellular proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "brain: 36.6" "Group enriched" "Detected in many" 4 "Astrocytes: 271.3;Bergmann glia: 478.7;Cone photoreceptor cells: 211.2" "Cell type enhanced" "Detected in many" "astrocyte: 210.1;Bergmann glia: 532.1" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 20.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070193 Enhanced NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 28: Astrocytes - Homeostasis & neuron support" 32 "HPA070193: " "unprognostic (5.55e-3)" "unprognostic (1.26e-1)" "unprognostic (2.25e-1)" "unprognostic (1.31e-1)" "unprognostic (3.32e-2)" "potential prognostic unfavorable (1.70e-7)" "unprognostic (2.03e-1)" "unprognostic (4.88e-2)" "potential prognostic unfavorable (3.92e-6)" "unprognostic (1.11e-1)" RGS21 ENSG00000253148 "Regulator of G protein signaling 21" Q2M5E4 1 192316992-192367285 "Predicted intracellular proteins" "Signal transduction inhibitor" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 5.6;Early spermatids: 2.8;Ependymal cells: 3.9;Late primary spermatocytes: 2.7;Mast cells: 4.4;Müller glia: 17.0;Respiratory ciliated cells: 7.2;Retinal ganglion cells: 7.7;Thymic myoid cells: 4.1" "Cell type enriched" "Detected in some" 5 "ependymal cell: 7.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA052843 Uncertain NA NA "Cluster 24: Non-specific - Unknown function" "Cluster 46: Skeletal myocytes - Muscle structure & formation" "HPA052843: " RGS22 "CT145, DKFZP434I092, PRTD-NY2" ENSG00000132554 "Regulator of G protein signaling 22" Q8NE09 8 99960936-100131268 "Predicted intracellular proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "testis: 57.3" "Cell type enhanced" "Detected in many" "Early spermatids: 755.8;Ependymal cells: 526.7;Fallopian tube ciliated cells: 228.7;Late primary spermatocytes: 331.8;Late spermatids: 2834.8;Leydig cells: 432.6;Peritubular myoid cells: 205.4;Respiratory ciliated cells: 417.1" "Group enriched" "Detected in many" 4 "choroid plexus epithelial cell: 148.9;ependymal cell: 590.4" "Cancer enhanced" "Detected in some" "Breast Invasive Carcinoma (TCGA): 2.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Lung - Respiratory ciliated cells, Prostate - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA053026 Supported "Nucleoli fibrillar center,Actin filaments,Cytosol" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" "Nucleoli fibrillar center" "Actin filaments, Cytosol" "HPA053026: " "unprognostic (3.67e-2)" "unprognostic (9.21e-2)" "unprognostic (6.61e-3)" "potential prognostic unfavorable (1.33e-4)" "unprognostic (1.01e-1)" "unprognostic (3.70e-1)" "unprognostic (4.85e-2)" RGS3 "C2PA, FLJ20370, PDZ-RGS3" ENSG00000138835 "Regulator of G protein signaling 3" P49796 9 113444731-113597743 "Plasma proteins, Predicted intracellular proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 142.2" "Cell type enhanced" "Detected in many" "Cholangiocytes: 101.8;Distal convoluted tubule cells: 116.4;Megakaryocytes: 98.9;Vascular endothelial cells: 107.2" "Cell type enhanced" "Detected in all" "endothelial cell: 136.1;ependymal cell: 88.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 4 "granulocytes: 19.0;NK-cells: 42.5;T-cells: 24.9" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Minor Salivary Gland - Endothelial cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" HPA044234 Supported "Plasma membrane" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 4 "Plasma membrane" "HPA044234: " "unprognostic (1.39e-1)" "potential prognostic unfavorable (2.68e-4)" "unprognostic (3.29e-1)" "unprognostic (1.50e-3)" "unprognostic (5.96e-2)" "unprognostic (4.42e-3)" "unprognostic (1.54e-2)" "unprognostic (4.75e-2)" "unprognostic (1.19e-2)" "unprognostic (1.59e-3)" "unprognostic (1.37e-1)" "unprognostic (1.34e-2)" "unprognostic (5.99e-2)" "potential prognostic unfavorable (2.68e-4)" "unprognostic (1.88e-2)" "unprognostic (3.69e-2)" "unprognostic (1.57e-2)" "unprognostic (1.32e-3)" "unprognostic (1.79e-1)" "unprognostic (2.27e-1)" "unprognostic (2.79e-2)" "unprognostic (1.13e-1)" "unprognostic (3.17e-1)" "unprognostic (3.20e-1)" "unprognostic (2.82e-2)" "unprognostic (1.10e-1)" "unprognostic (5.47e-2)" "unprognostic (3.41e-1)" "unprognostic (8.81e-2)" "unprognostic (1.30e-1)" "unprognostic (2.19e-1)" RGS4 SCZD9 ENSG00000117152 "Regulator of G protein signaling 4" P49798 1 163068775-163076802 "Disease related genes, Predicted intracellular proteins" "Signal transduction inhibitor" Schizophrenia "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 192.4" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 53.2;Brain excitatory neurons: 35.7;Brain inhibitory neurons: 27.7;Early spermatids: 18.6;Pancreatic islet cells: 146.2;Pituicytes/FSCs: 137.8;Retinal amacrine cells: 44.8" "Cell type enhanced" "Detected in all" "pericyte: 274.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Neuroblastoma: 415.4;thyroid cancer: 117.9" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030802 Approved Cytosol NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 11 Cytosol "HPA030802: " "unprognostic (1.48e-1)" "unprognostic (8.67e-2)" "unprognostic (1.23e-1)" "unprognostic (3.48e-2)" "unprognostic (1.19e-2)" "unprognostic (1.17e-1)" "unprognostic (2.12e-3)" "unprognostic (1.62e-1)" "unprognostic (2.15e-2)" "unprognostic (7.47e-2)" "unprognostic (2.07e-1)" "unprognostic (2.71e-1)" "unprognostic (1.03e-2)" "unprognostic (1.44e-1)" "unprognostic (5.90e-2)" "unprognostic (8.91e-2)" "unprognostic (1.95e-1)" "unprognostic (6.22e-2)" "unprognostic (7.44e-2)" "unprognostic (6.36e-3)" "unprognostic (2.25e-1)" "unprognostic (3.19e-2)" "unprognostic (2.59e-1)" "unprognostic (5.90e-2)" "unprognostic (9.75e-2)" "unprognostic (6.30e-2)" "unprognostic (4.58e-2)" "potential prognostic unfavorable (2.89e-4)" "unprognostic (7.53e-2)" "unprognostic (5.82e-2)" "unprognostic (5.86e-2)" RGS5 ENSG00000143248 "Regulator of G protein signaling 5" O15539 1 163111121-163321791 "Predicted intracellular proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "blood vessel: 1362.9" "Group enriched" "Detected in many" 8 "Adrenal medulla cells: 1223.2;Pericytes: 2480.1;Vascular smooth muscle cells: 1366.8" "Cell type enriched" "Detected in all" 4 "pericyte: 1979.3" "Cancer enriched" "Detected in all" 5 "Kidney Renal Clear Cell Carcinoma (TCGA): 800.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Neuroblastoma: 878.5" "Adipose subcutaneous - Endothelial cells, Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001821 Supported Supported Vesicles,Cytosol NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 47: Endothelial cells - Vasculature" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 110: Mural cells - ECM organization" 3 Cytosol Vesicles "HPA001821: " "unprognostic (9.53e-3)" "unprognostic (8.52e-2)" "unprognostic (9.32e-2)" "unprognostic (2.84e-1)" "unprognostic (1.40e-1)" "unprognostic (2.17e-1)" "unprognostic (2.22e-1)" "unprognostic (3.49e-1)" "unprognostic (5.12e-3)" "unprognostic (2.52e-1)" "validated prognostic favorable (7.07e-6)" "validated prognostic favorable (4.34e-5)" "potential prognostic unfavorable (5.71e-4)" "unprognostic (2.11e-2)" "unprognostic (2.92e-2)" "unprognostic (3.79e-2)" "unprognostic (1.76e-1)" "unprognostic (2.39e-3)" "unprognostic (2.27e-1)" "unprognostic (2.72e-1)" "unprognostic (2.47e-3)" "unprognostic (1.37e-1)" "unprognostic (1.73e-2)" "unprognostic (1.01e-1)" "unprognostic (4.76e-2)" "unprognostic (8.82e-2)" "unprognostic (3.76e-3)" "unprognostic (4.03e-3)" "unprognostic (1.73e-1)" "unprognostic (1.50e-1)" "unprognostic (4.52e-1)" RGS6 ENSG00000182732 "Regulator of G protein signaling 6" P49758 14 71932429-72566530 "Predicted intracellular proteins" "GTPase activation, Signal transduction inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.5;heart muscle: 10.5" "Cell type enhanced" "Detected in many" "Astrocytes: 395.2;Bergmann glia: 683.7;Brain excitatory neurons: 358.4;Brain inhibitory neurons: 393.2;Cardiomyocytes: 601.5;Corticotrophs: 741.2;Early spermatids: 349.3;Endometrial glandular cells: 401.9;Epicardial cells: 350.2;Late spermatids: 531.1;Other brain neurons: 336.3;Pericytes: 494.0;Pituicytes/FSCs: 394.8;Platelets: 448.0;Renal connecting tubule cells: 439.6;Vascular smooth muscle cells: 1480.7" "Cell type enhanced" "Detected in all" "vascular associated smooth muscle cell: 2367.7" "Group enriched" "Detected in some" 4 "Glioblastoma Multiforme (TCGA): 12.0;Thyroid Carcinoma (TCGA): 5.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 5.5" "Adipose visceral - Endothelial cells, Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003067 Uncertain Approved Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 35: Non-specific - Mixed function" "Cluster 24: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 103: Non-specific - Basic cellular processes" 6 Nucleoplasm "Nucleoli, Vesicles" "HPA003067: " "unprognostic (5.10e-2)" "unprognostic (1.19e-3)" "unprognostic (1.04e-1)" "unprognostic (4.47e-2)" "unprognostic (2.07e-3)" "unprognostic (3.61e-2)" "unprognostic (1.08e-2)" "unprognostic (8.00e-2)" "unprognostic (1.84e-1)" "unprognostic (5.19e-2)" "unprognostic (2.91e-3)" "unprognostic (7.48e-2)" RGS7 ENSG00000182901 "Regulator of G protein signaling 7" P49802 1 240767636-241357374 "Plasma proteins, Predicted intracellular proteins" "GTPase activation, Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 22.3" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 851.0;Astrocytes: 578.5;Brain excitatory neurons: 1531.1;Brain inhibitory neurons: 1407.1;Neuroendocrine cells: 615.5;Oligodendrocyte progenitor cells: 843.8;Other brain neurons: 1071.8;Pancreatic islet cells: 692.4;Retinal bipolar cells: 1084.3;Retinal ganglion cells: 548.5;Retinal horizontal cells: 1718.9;Somatotrophs: 473.3;Thyrotrophs: 640.9" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 3.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Pancreas - Alpha cells, Pancreas - Beta cells, Spleen - B-cells (Spleen), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB017561 Enhanced Supported Mitochondria,Cytosol NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 34: Non-specific - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" 3 Cytosol Mitochondria "CAB017561: " "unprognostic (3.74e-1)" "unprognostic (8.59e-3)" "unprognostic (1.81e-2)" "unprognostic (1.46e-1)" "unprognostic (2.03e-2)" "unprognostic (2.12e-2)" "unprognostic (2.63e-1)" "potential prognostic favorable (1.63e-4)" "unprognostic (6.87e-2)" "unprognostic (5.70e-2)" RGS7BP R7BP ENSG00000186479 "Regulator of G protein signaling 7 binding protein" Q6MZT1 5 64506015-64612319 "Predicted intracellular proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.7" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 85.1;Brain excitatory neurons: 125.0;Brain inhibitory neurons: 181.1;Lactotrophs: 58.2;Oligodendrocyte progenitor cells: 85.1;Other brain neurons: 78.8;Retinal amacrine cells: 135.0;Retinal ganglion cells: 127.5;Thyrotrophs: 135.5;Vascular smooth muscle cells: 68.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Rhabdoid: 2.0" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Adrenal gland - Fibroblasts, Kidney - Fibroblasts, Minor Salivary Gland - Minor salivary glandular cells, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039600 Approved Uncertain "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 109: Neurons - Neuronal signaling" 2 "Plasma membrane, Cytosol" "Actin filaments" "HPA039600: " "unprognostic (9.38e-2)" "unprognostic (2.01e-1)" "potential prognostic favorable (7.19e-4)" "potential prognostic favorable (3.17e-5)" "unprognostic (4.60e-3)" "unprognostic (1.44e-2)" "unprognostic (1.71e-2)" "unprognostic (1.15e-1)" "unprognostic (3.79e-3)" RGS8 "MGC119067, MGC119068, MGC119069" ENSG00000135824 "Regulator of G protein signaling 8" P57771 1 182641816-182684587 "Predicted intracellular proteins" "GTPase activation, Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 26.7;retina: 28.2" "Cell type enhanced" "Detected in some" "Brain inhibitory neurons: 43.9;Early spermatids: 23.0;Lactotrophs: 36.7;Late spermatids: 34.7;Retinal amacrine cells: 107.2;Retinal bipolar cells: 178.1;Somatotrophs: 13.9;Thyrotrophs: 35.0" "Cell type enhanced" "Detected in many" "medium spiny neuron: 79.5;thalamic excitatory: 67.2" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 1.5;Testicular Germ Cell Tumor (TCGA): 2.2;Thyroid Carcinoma (TCGA): 2.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 2.4;ovarian cancer: 7.3" "Adipose visceral - Mesothelial cells, Pituitary gland - Lactotropes, Testis - Early spermatids, Testis - Late spermatids" "Region enhanced" "Detected in all" "cerebellum: 425.5" "Low region specificity" "Detected in all" HPA076764 Enhanced Approved "Vesicles,Plasma membrane" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 1 "Vesicles, Plasma membrane" "HPA076764: " "unprognostic (3.54e-1)" "unprognostic (3.19e-2)" "unprognostic (1.72e-1)" "unprognostic (5.55e-2)" RGS9 "MGC111763, MGC26458, PERRS, RGS9L" ENSG00000108370 "Regulator of G protein signaling 9" O75916 17 65100812-65227703 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Sensory transduction, Vision" "Signal transduction inhibitor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 62.9" "Group enriched" "Detected in many" 4 "Cone photoreceptor cells: 691.4;Rod photoreceptor cells: 906.3" "Cell type enhanced" "Detected in many" "eccentric medium spiny neuron: 180.9;medium spiny neuron: 375.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "basal ganglia: 42.2" "Group enriched" "Detected in some" 6 "gdT-cell: 9.8;MAIT T-cell: 2.5;memory CD8 T-cell: 6.8;naive CD8 T-cell: 3.2;NK-cell: 4.0" "Group enriched" "Detected in many" 42 "NK-cells: 4.0;T-cells: 9.8" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Smooth muscle cells, Stomach - Fibroblasts" "Region enriched" "Detected in all" 9 "basal ganglia: 248.2" "Region enriched" "Detected in all" 10 "basal ganglia: 139.6" "HPA013550, HPA014137" Enhanced Supported Uncertain Nucleoplasm,Vesicles NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 79: Photoreceptor cells - Phototransduction" 5 Nucleoplasm Vesicles "HPA013550: , HPA014137: " "unprognostic (1.76e-3)" "unprognostic (1.30e-1)" "unprognostic (9.35e-2)" "unprognostic (4.79e-3)" "unprognostic (2.95e-3)" "unprognostic (2.23e-1)" "unprognostic (2.10e-1)" "unprognostic (2.35e-2)" "unprognostic (2.92e-2)" "unprognostic (8.78e-2)" "potential prognostic unfavorable (2.24e-4)" "potential prognostic favorable (4.13e-4)" "unprognostic (2.55e-2)" "unprognostic (1.50e-1)" RGS9BP "FLJ45744, PERRS, R9AP" ENSG00000186326 "Regulator of G protein signaling 9 binding protein" Q6ZS82 19 32675848-32678300 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Sensory transduction, Vision" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "choroid plexus: 11.8;retina: 16.1;skeletal muscle: 8.4" "Group enriched" "Detected in some" 4 "Cone photoreceptor cells: 35.2;Retinal bipolar cells: 17.0;Retinal pigment epithelial cells: 38.4;Rod photoreceptor cells: 37.2" "Cell type enriched" "Detected in single" 7 "choroid plexus epithelial cell: 5.0" "Not detected" "Not detected" "Region enriched" "Detected in all" 8 "choroid plexus: 62.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA049791 Enhanced Approved "Nucleoli,Plasma membrane,Mid piece,Principal piece,End piece" NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 36: Choroid plexus - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 79: Photoreceptor cells - Phototransduction" "Plasma membrane" "Nucleoli, Mid piece, Principal piece, End piece" "HPA049791: " "unprognostic (2.51e-2)" RGSL1 RGSL2 ENSG00000121446 "Regulator of G protein signaling like 1" A5PLK6 1 182409192-182560599 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "testis: 4.6" "Group enriched" "Detected in some" 24 "Early spermatids: 178.5;Late primary spermatocytes: 137.2;Late spermatids: 48.2" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" "unprognostic (1.22e-2)" "unprognostic (1.22e-2)" RHAG "CD241, RH50A, SLC42A1" ENSG00000112077 "Rh associated glycoprotein" Q02094 6 49605175-49636839 "CD markers, Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ammonia transport, Transport" "Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 53 "bone marrow: 112.6" "Cell type enriched" "Detected in some" 5 "Erythrocyte progenitors: 433.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Leukemia: 107.7" "Liver - Erythroid cells, Lung - Neutrophils_1, Spleen - Erythrocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA046051, HPA055331" Approved Approved "Endoplasmic reticulum" NA NA 88000 "Cluster 15: Bone marrow - Innate immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 5 "Endoplasmic reticulum" "HPA046051: , HPA055331: " RHBDD1 DKFZp547E052 ENSG00000144468 "Rhomboid domain containing 1" Q8TEB9 2 226835581-226999215 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Differentiation, Spermatogenesis" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 261.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013972, HPA057125" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 32: Basophils - Transcription" "Cluster 80: Thymus - Adaptive immune response" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 29 "Endoplasmic reticulum" "HPA013972: , HPA057125: " "unprognostic (1.58e-2)" "unprognostic (1.92e-2)" "unprognostic (5.66e-2)" "unprognostic (9.31e-2)" "unprognostic (2.58e-2)" "unprognostic (3.50e-2)" "unprognostic (1.59e-1)" "unprognostic (3.93e-2)" "unprognostic (1.34e-1)" "unprognostic (3.95e-2)" "potential prognostic favorable (3.43e-6)" "unprognostic (1.85e-2)" "unprognostic (6.31e-2)" "unprognostic (5.37e-3)" "unprognostic (2.42e-1)" "unprognostic (4.69e-2)" "unprognostic (6.02e-2)" "unprognostic (3.20e-2)" "unprognostic (3.24e-2)" "unprognostic (5.97e-2)" "unprognostic (2.26e-1)" "unprognostic (4.98e-3)" "unprognostic (3.52e-2)" "unprognostic (1.67e-1)" "unprognostic (6.60e-2)" "unprognostic (2.10e-2)" "unprognostic (2.01e-1)" "unprognostic (1.32e-2)" "unprognostic (2.07e-1)" "unprognostic (2.24e-1)" "unprognostic (1.08e-1)" RHBDD2 "NPD007, RHBDL7" ENSG00000005486 "Rhomboid domain containing 2" Q6NTF9 7 75842602-75888926 "Enzymes, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 348.9;choroid plexus: 356.5" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 178.5;Late spermatids: 530.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 400.9" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045074, HPA051960" Uncertain Enhanced "Golgi apparatus" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 39: Non-specific - Transcription" "Cluster 58: Mast cells - Allergic inflammatory responses" 2 "Golgi apparatus" "HPA045074: , HPA051960: " "unprognostic (8.91e-2)" "unprognostic (1.13e-1)" "unprognostic (3.33e-1)" "unprognostic (1.23e-1)" "unprognostic (3.03e-2)" "unprognostic (3.27e-2)" "potential prognostic unfavorable (2.33e-4)" "unprognostic (7.28e-3)" "unprognostic (9.31e-2)" "unprognostic (3.32e-1)" "potential prognostic unfavorable (5.11e-5)" "unprognostic (1.13e-2)" "unprognostic (1.45e-3)" "unprognostic (1.03e-2)" "potential prognostic unfavorable (4.27e-4)" "unprognostic (5.16e-2)" "unprognostic (1.59e-1)" "unprognostic (3.30e-2)" "unprognostic (4.36e-2)" "unprognostic (2.53e-1)" "unprognostic (3.48e-3)" "unprognostic (8.84e-2)" "unprognostic (2.79e-1)" "unprognostic (5.89e-2)" "unprognostic (3.10e-3)" "unprognostic (1.82e-1)" "unprognostic (9.88e-2)" "unprognostic (3.50e-1)" "unprognostic (6.49e-2)" "unprognostic (3.66e-1)" "unprognostic (8.20e-2)" RHBDD3 "C22orf3, PTAG" ENSG00000100263 "Rhomboid domain containing 3" Q9Y3P4 22 29259872-29268209 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 67.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043979 Approved Approved Microtubules NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 70: Non-specific - Protein processing" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 66: Non-specific - Mitochondria" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 1 Microtubules "HPA043979: " "unprognostic (3.66e-2)" "unprognostic (9.46e-2)" "unprognostic (2.24e-1)" "unprognostic (5.44e-2)" "unprognostic (3.45e-1)" "unprognostic (3.15e-2)" "unprognostic (9.83e-2)" "unprognostic (4.87e-2)" "unprognostic (3.04e-2)" "unprognostic (7.34e-2)" "validated prognostic unfavorable (4.94e-4)" "validated prognostic unfavorable (3.95e-5)" "unprognostic (1.57e-1)" "unprognostic (4.75e-3)" "unprognostic (1.40e-1)" "unprognostic (1.26e-1)" "unprognostic (8.12e-2)" "potential prognostic favorable (9.30e-4)" "unprognostic (3.96e-2)" "unprognostic (3.19e-1)" "unprognostic (6.31e-2)" "unprognostic (1.71e-2)" "unprognostic (7.13e-2)" "unprognostic (1.84e-1)" "unprognostic (1.94e-2)" "unprognostic (1.79e-2)" "unprognostic (3.27e-1)" "unprognostic (4.06e-3)" "unprognostic (2.00e-1)" "unprognostic (4.43e-2)" "unprognostic (5.89e-3)" RHBDF1 "C16orf8, Dist1, EGFR-RS, FLJ2235, iRhom1" ENSG00000007384 "Rhomboid 5 homolog 1" Q96CC6 16 58059-76355 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast lactating cells: 38.4;Esophageal apical cells: 49.4;Pancreatic duct cells: 32.7;Schwann cells: 39.3;Syncytiotrophoblasts: 40.9" "Group enriched" "Detected in many" 5 "astrocyte: 17.5;Bergmann glia: 16.7;committed oligodendrocyte precursor: 31.5;endothelial cell: 15.8;fibroblast: 27.9;oligodendrocyte precursor cell: 23.4;pericyte: 26.9;vascular associated smooth muscle cell: 22.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077399 Uncertain Vesicles NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 19: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 61: Schwann cells & Melanocytes - Mixed function" Vesicles "HPA077399: " "unprognostic (1.75e-2)" "unprognostic (5.93e-2)" "unprognostic (1.53e-1)" "unprognostic (5.29e-2)" "unprognostic (2.07e-2)" "unprognostic (2.03e-1)" "unprognostic (8.45e-2)" "potential prognostic unfavorable (5.56e-6)" "unprognostic (3.07e-1)" "unprognostic (7.43e-3)" "potential prognostic unfavorable (5.20e-5)" "unprognostic (2.30e-3)" "unprognostic (1.92e-1)" "unprognostic (1.00e-2)" "unprognostic (3.75e-2)" "unprognostic (8.60e-2)" "unprognostic (2.21e-2)" "unprognostic (7.67e-3)" "unprognostic (1.61e-1)" "unprognostic (9.13e-2)" "unprognostic (1.37e-1)" "unprognostic (3.71e-2)" "potential prognostic unfavorable (4.57e-4)" "unprognostic (5.29e-2)" "unprognostic (2.80e-1)" "potential prognostic favorable (2.31e-4)" "unprognostic (1.02e-1)" "unprognostic (1.28e-1)" "unprognostic (1.05e-1)" "unprognostic (4.84e-2)" "unprognostic (2.84e-1)" RHBDF2 "FLJ22341, iRhom2, RHBDL5, RHBDL6, TOC, TOCG" ENSG00000129667 "Rhomboid 5 homolog 2" Q6PJF5 17 76470891-76501790 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Growth factor binding" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 112.5;Hofbauer cells: 84.9;Innate lymphoid cells: 88.5;Macrophages: 138.9;Microglia: 321.0;monocytes: 132.7;Neutrophils: 73.9;pDCs: 66.9" "Cell type enriched" "Detected in many" 6 "central nervous system macrophage: 386.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Macrophages, Spleen - B-cells (Spleen)" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA018080 Uncertain NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 4 "HPA018080: " "unprognostic (2.22e-2)" "unprognostic (2.57e-1)" "unprognostic (3.45e-2)" "potential prognostic unfavorable (2.51e-4)" "unprognostic (1.03e-1)" "unprognostic (1.65e-1)" "unprognostic (6.51e-3)" "unprognostic (2.78e-1)" "unprognostic (1.12e-1)" "unprognostic (6.13e-2)" "unprognostic (3.03e-2)" "unprognostic (1.42e-2)" "unprognostic (1.57e-1)" "unprognostic (8.93e-3)" "unprognostic (1.77e-2)" "unprognostic (1.13e-2)" "unprognostic (2.41e-3)" "unprognostic (1.13e-1)" "unprognostic (3.58e-1)" "unprognostic (7.52e-2)" "unprognostic (1.81e-2)" "unprognostic (3.81e-2)" "unprognostic (6.06e-3)" "unprognostic (2.16e-1)" "unprognostic (2.71e-1)" "potential prognostic favorable (2.64e-4)" "unprognostic (1.49e-1)" "unprognostic (7.28e-2)" "unprognostic (3.65e-2)" "unprognostic (4.15e-2)" "unprognostic (2.64e-1)" RHBDL1 "RHBDL, RRP" ENSG00000103269 "Rhomboid like 1" O75783 16 675671-678268 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 36.5" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 38.2;Brain inhibitory neurons: 35.6;Corticotrophs: 36.6;Epididymal basal cells: 39.0;Epididymal principal cells: 28.1;Other brain neurons: 47.0;Respiratory basal cells: 18.4;Retinal amacrine cells: 29.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030359, HPA030360, HPA046593" Uncertain Approved Nucleoplasm No No "Cluster 43: Non-specific - Transcription & Translation" "Cluster 27: Cerebellum - Synaptic function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 98: Neurons - Neurotransmission & signaling" 9 Nucleoplasm "HPA030359: , HPA030360: , HPA046593: " "unprognostic (3.38e-2)" "unprognostic (1.39e-2)" "unprognostic (8.59e-2)" "unprognostic (7.20e-2)" "unprognostic (2.05e-2)" "potential prognostic favorable (3.10e-4)" "unprognostic (3.53e-2)" "unprognostic (1.92e-1)" "unprognostic (1.42e-2)" "unprognostic (1.11e-1)" "unprognostic (1.72e-1)" "unprognostic (2.16e-2)" "unprognostic (3.51e-1)" "unprognostic (3.11e-3)" "unprognostic (7.87e-2)" "unprognostic (2.52e-1)" "unprognostic (1.69e-1)" "unprognostic (2.40e-1)" "unprognostic (1.83e-1)" "unprognostic (3.17e-3)" "unprognostic (5.70e-2)" "unprognostic (8.82e-2)" "unprognostic (2.49e-1)" "unprognostic (1.11e-1)" "unprognostic (3.59e-1)" "unprognostic (2.30e-2)" "unprognostic (1.35e-2)" "unprognostic (5.35e-2)" "unprognostic (2.99e-1)" "unprognostic (3.43e-2)" RHBDL2 FLJ20435 ENSG00000158315 "Rhomboid like 2" Q9NX52 1 38885807-38941830 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 20.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 123.4;Colonocytes: 105.1;Epicardial cells: 161.5;Esophageal apical cells: 319.3;Foveolar cells: 121.4;Prostatic hillock cells: 109.3;Salivary duct cells: 133.1;Salivary ionocytes: 106.4;Sertoli cells: 108.7;Urothelial cells: 124.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Prostate - Urothelial cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043807 Approved NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 6: Non-specific - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 69: Urothelial cells - Basic cellular functions" 1 "HPA043807: " "unprognostic (2.08e-2)" "unprognostic (1.65e-1)" "unprognostic (3.92e-1)" "unprognostic (1.67e-1)" "unprognostic (2.51e-1)" "unprognostic (1.35e-2)" "unprognostic (2.60e-2)" "unprognostic (3.94e-2)" "unprognostic (4.79e-2)" "unprognostic (4.63e-2)" "potential prognostic unfavorable (2.23e-6)" "unprognostic (7.72e-2)" "unprognostic (5.22e-2)" "potential prognostic unfavorable (6.02e-5)" "unprognostic (8.70e-2)" "unprognostic (1.45e-3)" "unprognostic (2.86e-1)" "unprognostic (4.89e-2)" "unprognostic (1.91e-1)" "unprognostic (1.64e-1)" "unprognostic (4.40e-3)" "unprognostic (2.51e-2)" "unprognostic (2.34e-2)" "unprognostic (6.14e-2)" "potential prognostic unfavorable (5.82e-4)" "unprognostic (3.29e-2)" "unprognostic (4.45e-2)" "unprognostic (2.43e-1)" "unprognostic (1.75e-1)" "unprognostic (5.37e-2)" RHBDL3 "RHBDL4, VRHO" ENSG00000141314 "Rhomboid like 3" P58872 17 32265832-32324659 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.2;heart muscle: 14.4;retina: 24.2" "Cell type enhanced" "Detected in many" "Astrocytes: 89.8;Cone photoreceptor cells: 111.8;Gonadotrophs: 73.9;Oligodendrocyte progenitor cells: 165.3;Retinal bipolar cells: 119.0;Retinal ganglion cells: 262.7;Retinal horizontal cells: 767.3;Rod photoreceptor cells: 318.1" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 212.2;oligodendrocyte precursor cell: 182.2" "Cancer enriched" "Detected in many" 5 "Glioblastoma Multiforme (TCGA): 11.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA059607 Uncertain NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 1: Neuronal - Visual perception" "Cluster 109: Neurons - Neuronal signaling" "HPA059607: " "unprognostic (1.02e-1)" "unprognostic (7.46e-2)" "unprognostic (1.12e-1)" "unprognostic (9.88e-2)" "unprognostic (2.86e-1)" "potential prognostic favorable (1.60e-4)" "unprognostic (3.89e-2)" "unprognostic (3.45e-2)" "potential prognostic favorable (5.02e-4)" "unprognostic (4.98e-1)" "unprognostic (1.57e-1)" RHBG SLC42A2 ENSG00000132677 "Rh family B glycoprotein" Q9H310 1 156369211-156385219 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ammonia transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.0;kidney: 10.3" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 107.2;Epididymal clear cells: 53.1;Esophageal apical cells: 72.1;Granulosa cells: 36.5;Renal collecting duct intercalated cells: 333.2;Renal collecting duct principal cells: 38.3;Renal connecting tubule cells: 159.0" "Cell type enriched" "Detected in some" 30 "upper rhombic lip: 32.1" "Cancer enriched" "Detected in some" 5 "Kidney Chromophobe (TCGA): 33.7" "Region enriched" "Detected in single" 15 "cerebellum: 4.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Intercalated cells, Liver - Hepatocytes, Skin - Keratinocyte (granular), Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA042726, HPA048489" Enhanced Approved Nucleoplasm NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 35: Non-specific - DNA binding" "Cluster 18: Liver cancer - Metabolism" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" Nucleoplasm "HPA042726: , HPA048489: " "unprognostic (1.61e-1)" "unprognostic (1.81e-1)" "unprognostic (1.44e-1)" "potential prognostic unfavorable (2.45e-4)" "unprognostic (4.37e-1)" "unprognostic (1.63e-1)" "potential prognostic unfavorable (3.20e-4)" RHCE "CD240CE, RH" ENSG00000188672 "Rh blood group CcEe antigens" P18577 1 25362249-25430192 "Blood group antigen proteins, CD markers, Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "bone marrow: 45.7" "Group enriched" "Detected in many" 4 "Erythrocyte progenitors: 184.4;Erythrocytes: 58.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Leukemia: 5.4" "Minor Salivary Gland - Minor salivary glandular cells, Spleen - Erythrocytes, Testis - Spermatogonia" "HPA060951, HPA077385" Supported Uncertain "Nucleoplasm,Plasma membrane" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" "Nucleoplasm, Plasma membrane" "HPA060951: , HPA077385: " "unprognostic (4.87e-2)" "unprognostic (4.98e-1)" "unprognostic (2.49e-3)" "unprognostic (2.05e-1)" "unprognostic (8.61e-2)" "unprognostic (1.44e-1)" "unprognostic (7.86e-2)" "unprognostic (1.61e-1)" "unprognostic (6.98e-2)" "unprognostic (1.42e-3)" "unprognostic (3.32e-2)" "unprognostic (9.64e-2)" "unprognostic (1.09e-2)" "unprognostic (2.35e-1)" RHCG "C15orf6, PDRC2, RHGK, SLC42A3" ENSG00000140519 "Rh family C glycoprotein" Q9UBD6 15 89471398-89496589 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ammonia transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "cervix: 1080.1;esophagus: 3828.0;vagina: 1649.9" "Group enriched" "Detected in many" 9 "Esophageal apical cells: 45474.5;Esophageal suprabasal cells: 13016.7" "Cell type enhanced" "Detected in many" "deep-layer intratelencephalic: 12.0" "Cancer enriched" "Detected in many" 5 "Kidney Chromophobe (TCGA): 1345.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Gallbladder cancer: 21.0;head and neck cancer: 25.3" "Kidney - Intercalated cells, Prostate - Urothelial cells" "Region enriched" "Detected in many" 5 "olfactory bulb: 8.4" "Low region specificity" "Detected in many" "HPA041874, HPA043317" Enhanced NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 17 "HPA041874: , HPA043317: " "unprognostic (7.31e-3)" "unprognostic (2.26e-1)" "unprognostic (2.32e-1)" "unprognostic (2.26e-2)" "unprognostic (9.95e-2)" "unprognostic (1.84e-3)" "unprognostic (2.04e-2)" "potential prognostic favorable (1.71e-4)" "unprognostic (5.45e-2)" "unprognostic (4.76e-1)" "unprognostic (1.36e-1)" "unprognostic (2.01e-2)" "potential prognostic unfavorable (8.67e-5)" "unprognostic (7.12e-2)" "unprognostic (2.60e-1)" "unprognostic (1.27e-1)" "unprognostic (5.71e-3)" "potential prognostic unfavorable (2.31e-4)" "unprognostic (1.94e-1)" "unprognostic (1.96e-1)" "unprognostic (1.39e-1)" "unprognostic (2.92e-2)" RHD "CD240D, DIIIc, RH, Rh30a, Rh4, RhII, RhPI" ENSG00000187010 "Rh blood group D antigen" Q02161 1 25272393-25330445 "Blood group antigen proteins, CD markers, Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "bone marrow: 14.8" "Cell type enhanced" "Detected in many" "Epicardial cells: 163.7;Erythrocyte progenitors: 182.3;Fibro-adipogenic progenitors: 54.7;Platelets: 73.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 6.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 6.0" "Cancer enriched" "Detected in single" 4 "Leukemia: 3.0" "Minor Salivary Gland - Minor salivary glandular cells" "HPA060951, HPA077385" Supported Uncertain "Nucleoplasm,Plasma membrane" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 15: Bone marrow - Innate immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 1 "Nucleoplasm, Plasma membrane" "HPA060951: , HPA077385: " "unprognostic (7.23e-2)" "unprognostic (6.75e-2)" "unprognostic (3.51e-2)" "unprognostic (7.54e-2)" "unprognostic (7.03e-3)" RHEB RHEB2 ENSG00000106615 "Ras homolog, mTORC1 binding" Q15382 7 151466012-151520120 "Cancer-related genes, Essential proteins, Predicted intracellular proteins" Hydrolase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB019436 Uncertain NA NA 5600 "Cluster 42: Non-specific - Vesicular transport" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 39: Non-specific - Transcription" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 34 "CAB019436: " "unprognostic (7.24e-2)" "unprognostic (5.40e-2)" "unprognostic (1.88e-1)" "unprognostic (9.62e-2)" "unprognostic (2.60e-2)" "unprognostic (5.52e-2)" "unprognostic (3.70e-2)" "unprognostic (1.94e-1)" "unprognostic (1.59e-2)" "unprognostic (4.32e-2)" "unprognostic (2.72e-2)" "potential prognostic unfavorable (6.85e-5)" "potential prognostic unfavorable (1.69e-4)" "potential prognostic unfavorable (5.84e-6)" "unprognostic (2.95e-3)" "unprognostic (7.47e-2)" "unprognostic (2.06e-3)" "unprognostic (2.27e-2)" "unprognostic (6.21e-2)" "unprognostic (7.11e-2)" "unprognostic (1.53e-1)" "unprognostic (1.66e-3)" "unprognostic (3.67e-2)" "unprognostic (2.51e-2)" "unprognostic (6.04e-2)" "unprognostic (1.48e-1)" "unprognostic (5.86e-2)" "unprognostic (1.48e-1)" "unprognostic (2.25e-1)" "unprognostic (1.42e-1)" "unprognostic (5.46e-2)" RHEBL1 "FLJ25797, MGC34869, RHEB2" ENSG00000167550 "RHEB like 1" Q8TAI7 12 49064676-49070025 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.2" "Cell type enhanced" "Detected in many" "B-cells: 9.7;Differentiating spermatogonia: 10.5;Epididymal efferent duct ciliated cells: 16.8;Fallopian tube ciliated cells: 14.7;Granulosa cells: 39.7;NK-cells: 16.6;Oocytes: 27.6;Respiratory ciliated cells: 21.0" "Cell type enhanced" "Detected in many" "deep-layer intratelencephalic: 10.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 16.1" "Group enriched" "Detected in all" 5 "granulocytes: 16.1;T-cells: 10.5" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA053111, HPA061001" Uncertain Approved Nucleoplasm,Nucleoli,Centrosome NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 53: Neurons - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 11 Centrosome "Nucleoplasm, Nucleoli" "HPA053111: , HPA061001: " "unprognostic (1.15e-1)" "unprognostic (1.82e-1)" "unprognostic (3.44e-1)" "unprognostic (4.29e-2)" "unprognostic (1.04e-2)" "unprognostic (7.11e-2)" "unprognostic (1.34e-3)" "unprognostic (2.70e-1)" "unprognostic (1.31e-1)" "unprognostic (3.11e-2)" "unprognostic (8.49e-2)" "unprognostic (9.42e-3)" "unprognostic (2.32e-3)" "unprognostic (1.29e-1)" "unprognostic (4.46e-2)" "unprognostic (2.54e-2)" "unprognostic (1.17e-1)" "unprognostic (1.09e-1)" "unprognostic (3.25e-1)" "unprognostic (1.25e-2)" "unprognostic (3.30e-1)" "unprognostic (2.76e-3)" "unprognostic (2.90e-3)" "unprognostic (5.87e-2)" "unprognostic (8.58e-2)" "unprognostic (5.12e-2)" RHEX "C1orf186, FLJ16052" ENSG00000263961 "Regulator of hemoglobinization and erythroid cell expansion" Q6ZWK4 1 206053173-206102449 "Predicted membrane proteins" "Differentiation, Erythrocyte maturation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 22.9" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 393.8;Endometrial glandular cells: 1237.2;Endometrial luminal cells: 1014.0;Endometrial secretory cells: 295.3;Loop of henle epithelial cells: 312.3;Mast cells: 699.4;Papillary tip epithelial cells: 637.1;Proximal tubule cells: 1184.9;Renal collecting duct principal cells: 330.2" "Cell type enhanced" "Detected in single" "leukocyte: 2.0" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 130.9" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 152 "basophil: 1318.2" "Lineage enriched" "Detected in single" 1550 "granulocytes: 1318.2" "Cancer enhanced" "Detected in many" "Leukemia: 58.2" "Adipose subcutaneous - Mast cells, Adipose visceral - Mast cells, Colon - Mast cells, Minor Salivary Gland - Mast cells, Pituitary gland - Corticotropes" "Low region specificity" "Detected in all" HPA037859 Supported "Plasma membrane" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 22: Epididymis - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 51: Secretory epithelial cells - Mixed function" 6 "Plasma membrane" "HPA037859: " "unprognostic (3.71e-2)" "unprognostic (9.18e-2)" "unprognostic (2.39e-1)" "unprognostic (2.58e-1)" "unprognostic (1.29e-2)" "unprognostic (1.76e-2)" "unprognostic (2.50e-2)" "unprognostic (1.61e-3)" "unprognostic (1.29e-1)" "potential prognostic favorable (2.67e-5)" "unprognostic (9.00e-2)" "unprognostic (2.65e-1)" "unprognostic (7.30e-2)" "unprognostic (7.60e-2)" "unprognostic (1.74e-1)" "unprognostic (1.08e-2)" "unprognostic (2.27e-1)" "potential prognostic unfavorable (4.61e-4)" "unprognostic (1.41e-1)" "unprognostic (2.08e-1)" "unprognostic (3.23e-1)" RHNO1 "C12orf32, HKMT1188, MGC13204, RHINO" ENSG00000171792 "RAD9-HUS1-RAD1 interacting nuclear orphan 1" Q9BSD3 12 2876258-2889524 "Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Epididymal principal cells: 2.5;Erythrocyte progenitors: 1.9;Monocyte progenitors: 1.8;Paneth cells: 3.9;Plasma cells: 1.7;Thymocytes: 1.7" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA Yes "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 38: Non-specific - Transcription" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 13 "unprognostic (4.40e-2)" "unprognostic (8.00e-2)" "unprognostic (3.48e-1)" "unprognostic (4.64e-2)" "unprognostic (3.12e-1)" "unprognostic (4.80e-2)" "unprognostic (1.02e-1)" "unprognostic (1.19e-1)" "unprognostic (7.94e-3)" "unprognostic (1.67e-3)" "unprognostic (1.74e-2)" "unprognostic (1.05e-2)" "potential prognostic unfavorable (2.14e-5)" "potential prognostic unfavorable (9.76e-4)" "unprognostic (5.63e-3)" "unprognostic (3.15e-3)" "unprognostic (4.55e-1)" "unprognostic (1.90e-3)" "unprognostic (1.18e-1)" "unprognostic (4.30e-3)" "unprognostic (7.43e-3)" "unprognostic (1.76e-1)" "potential prognostic favorable (4.38e-4)" "unprognostic (9.90e-2)" "unprognostic (1.42e-2)" "unprognostic (2.63e-1)" "unprognostic (2.42e-1)" "unprognostic (6.82e-2)" "unprognostic (1.73e-1)" RHO "CSNBAD1, OPN2, RP4" ENSG00000163914 Rhodopsin P08100 3 129528639-129535344 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Sensory transduction, Vision" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Congenital stationary night blindness, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 8422 "retina: 3767.6" "Cell type enriched" "Detected in some" 22 "Rod photoreceptor cells: 2478.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in some" 4 "hippocampal formation: 9.7" "Region enhanced" "Detected in some" "cerebral cortex: 1.0;hippocampal formation: 1.5" "HPA013440, CAB022486, CAB034887, CAB034888" Enhanced NA NA "Cluster 42: Retina - Visual perception" "Cluster 53: Neurons - Mixed function" "Cluster 79: Photoreceptor cells - Phototransduction" 3 "CAB022486: , CAB034887: , CAB034888: , HPA013440: " RHOA "ARH12, ARHA, Rho12, RHOH12" ENSG00000067560 "Ras homolog family member A" P61586 3 49359139-49412998 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Cell cycle, Cell division, Host-virus interaction" Hydrolase "Cancer-related genes, Disease variant, Ectodermal dysplasia, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 98.6;Choroid plexus epithelial cells: 53.5;Distal convoluted tubule cells: 66.0;Ependymal cells: 58.8;Loop of henle epithelial cells: 78.0;Microglia: 107.5;Oligodendrocytes: 77.0;Other brain neurons: 52.2;Papillary tip epithelial cells: 95.2;Podocytes: 78.2;Proximal tubule cells: 65.3;Renal collecting duct intercalated cells: 84.0;Renal collecting duct principal cells: 77.7;Renal connecting tubule cells: 87.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005052 Approved Supported "Plasma membrane,Cytosol" NA NA 1600000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 102: Non-specific - Mixed function" 188 "Plasma membrane, Cytosol" "CAB005052: " "unprognostic (3.25e-2)" "unprognostic (9.84e-2)" "unprognostic (3.95e-1)" "unprognostic (8.00e-2)" "unprognostic (2.18e-2)" "unprognostic (3.32e-1)" "unprognostic (2.57e-1)" "unprognostic (6.23e-2)" "unprognostic (2.10e-1)" "potential prognostic unfavorable (2.40e-4)" "potential prognostic favorable (2.75e-7)" "unprognostic (9.18e-3)" "potential prognostic favorable (3.33e-4)" "validated prognostic unfavorable (2.85e-4)" "validated prognostic unfavorable (2.59e-4)" "unprognostic (1.05e-1)" "unprognostic (1.53e-3)" "unprognostic (8.79e-2)" "unprognostic (2.55e-2)" "unprognostic (1.25e-2)" "unprognostic (1.12e-1)" "unprognostic (8.62e-3)" "unprognostic (7.88e-2)" "unprognostic (1.68e-1)" "unprognostic (7.61e-2)" "unprognostic (1.91e-1)" "unprognostic (1.07e-1)" "unprognostic (7.86e-2)" "unprognostic (2.56e-1)" "unprognostic (1.48e-1)" "unprognostic (1.55e-2)" RHOB "ARH6, ARHB, MST081, RHOH6" ENSG00000143878 "Ras homolog family member B" P62745 2 20447074-20449440 "Cancer-related genes, Predicted intracellular proteins" "Angiogenesis, Apoptosis, Cell adhesion, Differentiation, Protein transport, Transport" "Developmental protein" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 1648.0" "Cell type enhanced" "Detected in all" "Epididymal principal cells: 899.3;Hepatocytes: 1696.8;Vascular smooth muscle cells: 1161.5" "Cell type enhanced" "Detected in all" "astrocyte: 390.1;Bergmann glia: 383.2;vascular associated smooth muscle cell: 525.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 5.6;eosinophil: 18.0;intermediate monocyte: 11.4;neutrophil: 21.6;non-classical monocyte: 13.4" "Group enriched" "Detected in many" 13 "granulocytes: 21.6;monocytes: 13.4" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 19: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 103: Non-specific - Basic cellular processes" 315 "unprognostic (6.28e-2)" "unprognostic (7.77e-2)" "unprognostic (4.83e-1)" "unprognostic (3.21e-3)" "unprognostic (3.09e-2)" "unprognostic (9.08e-2)" "unprognostic (3.23e-1)" "unprognostic (1.12e-1)" "unprognostic (1.81e-2)" "unprognostic (6.72e-2)" "validated prognostic favorable (1.95e-10)" "validated prognostic favorable (3.53e-6)" "unprognostic (3.26e-3)" "unprognostic (7.74e-3)" "potential prognostic favorable (1.60e-4)" "unprognostic (1.31e-1)" "unprognostic (9.33e-2)" "unprognostic (1.13e-1)" "unprognostic (7.61e-2)" "unprognostic (6.46e-2)" "unprognostic (2.24e-1)" "unprognostic (2.29e-1)" "unprognostic (3.21e-1)" "unprognostic (7.95e-2)" "unprognostic (3.44e-1)" "unprognostic (4.08e-3)" "unprognostic (1.39e-1)" "unprognostic (9.15e-2)" "unprognostic (2.00e-1)" "unprognostic (1.30e-2)" "unprognostic (8.84e-2)" RHOBTB1 KIAA0740 ENSG00000072422 "Rho related BTB domain containing 1" O94844 10 60869438-61001440 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 135.1" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 679.0;Cytotrophoblasts: 510.3;Gastric chief cells: 330.9;Mucous neck cells: 438.9;Myonuclei: 526.9;Proximal tubule cells: 991.8;Retinal horizontal cells: 883.5;Syncytiotrophoblasts: 1918.9" "Cell type enhanced" "Detected in all" "endothelial cell: 383.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Prostate - Fibroblasts, Skeletal muscle - Skeletal myocytes, Testis - Late spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040205, HPA040226" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 11: White matter - Signal transduction" "Cluster 18: Liver cancer - Metabolism" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 33 Nucleoplasm Cytosol "HPA040205: , HPA040226: " "unprognostic (2.37e-1)" "unprognostic (7.66e-2)" "unprognostic (5.83e-2)" "unprognostic (1.75e-2)" "unprognostic (4.76e-2)" "unprognostic (3.96e-3)" "unprognostic (2.27e-1)" "unprognostic (5.75e-3)" "unprognostic (1.38e-1)" "unprognostic (1.53e-1)" "potential prognostic favorable (1.09e-7)" "unprognostic (9.42e-2)" "unprognostic (7.63e-3)" "unprognostic (3.04e-3)" "unprognostic (1.21e-1)" "unprognostic (1.79e-1)" "unprognostic (1.73e-1)" "unprognostic (2.43e-2)" "unprognostic (1.02e-1)" "unprognostic (1.34e-1)" "unprognostic (3.86e-2)" "unprognostic (4.67e-2)" "unprognostic (1.12e-1)" "unprognostic (1.57e-1)" "unprognostic (3.18e-2)" "unprognostic (7.14e-3)" "unprognostic (1.74e-1)" "unprognostic (1.49e-1)" "unprognostic (8.00e-2)" "unprognostic (7.24e-2)" "unprognostic (9.29e-2)" RHOBTB2 "DBC2, KIAA0717" ENSG00000008853 "Rho related BTB domain containing 2" Q9BYZ6 8 22987417-23020509 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 163.4;Alveolar cells type 2: 230.2;Enterocytes: 74.9;Epicardial cells: 141.0;Podocytes: 89.3;Transitional alveolar cells: 124.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Minor Salivary Gland - Endothelial cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060938 Approved Approved "Plasma membrane" NA NA "Cluster 32: Basophils - Transcription" "Cluster 73: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 81: Alveolar cells - Lung function" 7 "Plasma membrane" "HPA060938: " "unprognostic (3.61e-3)" "unprognostic (1.38e-3)" "unprognostic (1.03e-1)" "unprognostic (2.85e-2)" "unprognostic (1.16e-1)" "unprognostic (1.55e-1)" "unprognostic (1.02e-2)" "unprognostic (8.71e-2)" "unprognostic (5.93e-2)" "unprognostic (2.57e-2)" "validated prognostic favorable (7.98e-7)" "validated prognostic favorable (5.56e-4)" "unprognostic (1.61e-1)" "unprognostic (7.31e-2)" "unprognostic (1.09e-1)" "unprognostic (7.28e-3)" "unprognostic (5.92e-2)" "unprognostic (2.06e-3)" "unprognostic (4.81e-2)" "unprognostic (1.28e-2)" "unprognostic (4.75e-2)" "unprognostic (9.21e-2)" "unprognostic (2.31e-2)" "potential prognostic favorable (7.00e-4)" "unprognostic (4.10e-1)" "unprognostic (4.00e-2)" "unprognostic (3.55e-2)" "unprognostic (2.29e-1)" "unprognostic (2.80e-1)" "unprognostic (5.42e-2)" "unprognostic (1.02e-1)" RHOBTB3 KIAA0878 ENSG00000164292 "Rho related BTB domain containing 3" O94955 5 95713522-95824383 "Predicted intracellular proteins" Transport Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 801.7;Leydig cells: 791.2;Retinal pigment epithelial cells: 865.4" "Cell type enhanced" "Detected in all" "astrocyte: 303.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 7.4" "Group enriched" "Detected in many" 4 "granulocytes: 7.4;T-cells: 1.9" "Cancer enhanced" "Detected in all" "testis cancer: 291.0" "Adrenal gland - Adrenal cortex cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000265 Uncertain Vesicles NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 36: Brain & Liver - Signaling" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 89: Adipocytes - Lipid metabolism" 43 Vesicles "HPA000265: " "unprognostic (3.55e-2)" "unprognostic (9.26e-2)" "unprognostic (1.61e-2)" "unprognostic (1.45e-1)" "unprognostic (1.62e-2)" "unprognostic (7.63e-3)" "unprognostic (3.15e-1)" "unprognostic (4.44e-2)" "unprognostic (1.52e-1)" "unprognostic (9.65e-2)" "unprognostic (3.67e-2)" "unprognostic (1.29e-1)" "unprognostic (1.33e-2)" "unprognostic (2.09e-1)" "unprognostic (1.82e-1)" "unprognostic (9.75e-3)" "unprognostic (1.54e-1)" "unprognostic (2.11e-1)" "unprognostic (8.99e-2)" "unprognostic (6.33e-2)" "potential prognostic unfavorable (6.82e-5)" "unprognostic (9.01e-2)" "unprognostic (7.83e-2)" "unprognostic (3.03e-1)" "unprognostic (1.70e-1)" "unprognostic (3.11e-2)" "unprognostic (1.77e-1)" "unprognostic (3.68e-3)" "unprognostic (1.42e-1)" "unprognostic (1.63e-1)" "unprognostic (5.33e-2)" RHOC "ARH9, ARHC" ENSG00000155366 "Ras homolog family member C" P08134 1 112701127-112707434 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 854.1;Decidual stromal cells: 549.8;Enterocytes: 854.2;Epididymal basal cells: 431.6;Epididymal principal cells: 692.2;Extravillous trophoblasts: 655.0" "Cell type enhanced" "Detected in many" "endothelial cell: 116.9;pericyte: 118.1;vascular associated smooth muscle cell: 78.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 1403.4" "Lineage enriched" "Detected in all" 4 "monocytes: 1403.4" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051461 Uncertain NA NA 1200000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 44: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 34 "HPA051461: " "unprognostic (7.56e-2)" "unprognostic (1.16e-2)" "unprognostic (1.50e-1)" "unprognostic (1.53e-2)" "unprognostic (4.25e-2)" "unprognostic (3.32e-1)" "unprognostic (3.41e-2)" "unprognostic (3.21e-2)" "unprognostic (5.82e-2)" "unprognostic (9.08e-2)" "unprognostic (8.39e-3)" "unprognostic (3.81e-1)" "unprognostic (2.06e-2)" "validated prognostic unfavorable (2.90e-4)" "validated prognostic unfavorable (8.90e-4)" "validated prognostic unfavorable (1.13e-4)" "validated prognostic unfavorable (2.60e-5)" "unprognostic (3.42e-1)" "unprognostic (9.02e-3)" "unprognostic (1.28e-1)" "unprognostic (2.40e-1)" "unprognostic (1.06e-3)" "unprognostic (2.35e-1)" "unprognostic (9.15e-2)" "unprognostic (1.14e-1)" "unprognostic (2.05e-1)" "unprognostic (2.89e-1)" "unprognostic (7.71e-2)" "unprognostic (3.21e-1)" "unprognostic (6.42e-2)" "unprognostic (5.09e-3)" RHOD "ARHD, Rho, RhoHP1" ENSG00000173156 "Ras homolog family member D" O00212 11 67056847-67072017 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 185.7;liver: 124.9" "Cell type enriched" "Detected in many" 4 "Esophageal apical cells: 2152.5" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 17.8;vascular associated smooth muscle cell: 7.6" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 7 "choroid plexus: 33.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "cerebellum: 14.9;pons and medulla: 5.1" "Low region specificity" "Detected in some" NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 84: Apical squamous epithelium - Cornification" 20 "unprognostic (7.17e-2)" "unprognostic (6.41e-2)" "unprognostic (2.27e-2)" "unprognostic (5.84e-3)" "unprognostic (1.57e-1)" "unprognostic (2.60e-2)" "validated prognostic unfavorable (4.56e-4)" "validated prognostic unfavorable (2.26e-4)" "unprognostic (1.98e-1)" "unprognostic (5.18e-2)" "unprognostic (1.51e-1)" "unprognostic (1.86e-1)" "unprognostic (1.56e-1)" "unprognostic (1.39e-1)" "unprognostic (5.89e-3)" "unprognostic (1.01e-3)" "potential prognostic unfavorable (7.35e-4)" "unprognostic (6.98e-3)" "unprognostic (6.55e-3)" "unprognostic (2.56e-1)" "unprognostic (1.68e-2)" "validated prognostic unfavorable (3.38e-4)" "validated prognostic unfavorable (8.89e-4)" "unprognostic (4.80e-2)" "unprognostic (2.34e-1)" "potential prognostic favorable (5.32e-4)" "unprognostic (3.10e-2)" "unprognostic (2.28e-1)" "unprognostic (2.51e-1)" "unprognostic (2.94e-1)" "unprognostic (4.53e-2)" RHOF "ARHF, FLJ20247, RIF" ENSG00000139725 "Ras homolog family member F, filopodia associated" Q9HBH0 12 121777754-121803403 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 124.5;cDC: 101.9;Colonocytes: 165.4;Enterocytes: 189.6;Esophageal apical cells: 152.6;Foveolar cells: 115.2;Megakaryocytes: 358.5;Platelets: 341.4" "Cell type enhanced" "Detected in many" "leukocyte: 50.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045912, HPA076019" Enhanced Supported Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 8 "Nucleoplasm, Golgi apparatus" "HPA045912: , HPA076019: " "unprognostic (3.43e-1)" "unprognostic (1.55e-1)" "unprognostic (3.52e-2)" "unprognostic (1.15e-1)" "unprognostic (2.38e-1)" "unprognostic (4.76e-2)" "unprognostic (2.51e-1)" "potential prognostic favorable (6.54e-4)" "potential prognostic favorable (8.32e-6)" "unprognostic (1.14e-1)" "potential prognostic unfavorable (4.37e-4)" "unprognostic (3.05e-3)" "unprognostic (2.19e-1)" "potential prognostic unfavorable (9.02e-4)" "unprognostic (2.00e-1)" "potential prognostic unfavorable (5.18e-6)" "unprognostic (8.94e-2)" "unprognostic (2.86e-2)" "unprognostic (1.76e-2)" "unprognostic (7.04e-2)" "unprognostic (3.40e-1)" "potential prognostic unfavorable (2.54e-4)" "unprognostic (6.71e-2)" "unprognostic (1.65e-1)" "unprognostic (1.54e-2)" "unprognostic (4.70e-2)" "unprognostic (1.26e-1)" "unprognostic (2.54e-1)" "unprognostic (3.76e-2)" "unprognostic (3.69e-3)" "unprognostic (1.54e-1)" RHOG "ARHG, MGC125835, MGC125836" ENSG00000177105 "Ras homolog family member G" P84095 11 3826978-3840959 "Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 257.8" "Cell type enhanced" "Detected in many" "cDC: 207.2;Esophageal apical cells: 512.9;Hofbauer cells: 273.9;Kupffer cells: 415.1;monocytes: 263.4;Neutrophil progenitors: 297.3;Neutrophils: 894.9" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 40.9;leukocyte: 54.3;oligodendrocyte: 81.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Lung - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039871 Enhanced NA NA 470000 "Cluster 7: Non-specific - Innate immune response" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 30: White matter - Myelination" "Cluster 49: HMC-1 - Innate immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 20 "HPA039871: " "unprognostic (5.49e-1)" "unprognostic (7.70e-2)" "unprognostic (5.09e-2)" "unprognostic (2.34e-1)" "unprognostic (5.87e-3)" "unprognostic (1.90e-1)" "unprognostic (5.44e-3)" "unprognostic (2.33e-2)" "unprognostic (1.84e-1)" "unprognostic (2.67e-1)" "unprognostic (6.09e-3)" "unprognostic (1.70e-1)" "unprognostic (1.34e-1)" "potential prognostic unfavorable (8.47e-4)" "unprognostic (1.19e-1)" "unprognostic (1.26e-1)" "unprognostic (3.47e-3)" "unprognostic (1.07e-1)" "unprognostic (1.58e-1)" "unprognostic (9.65e-3)" "unprognostic (2.74e-1)" "unprognostic (1.13e-1)" "unprognostic (2.59e-1)" "unprognostic (3.17e-1)" "unprognostic (6.97e-3)" "unprognostic (2.70e-1)" "unprognostic (1.08e-1)" "unprognostic (1.34e-1)" "unprognostic (1.89e-2)" "unprognostic (2.87e-1)" "unprognostic (2.12e-2)" RHOH "ARHH, TTF" ENSG00000168421 "Ras homolog family member H" Q15669 4 40191011-40246967 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "bone marrow: 69.7;lymphoid tissue: 99.1" "Cell type enhanced" "Detected in many" "B-cells: 771.4;Hematopoietic stem cells: 342.6;Innate lymphoid cells: 328.4;Mast cells: 1000.2;Neutrophil progenitors: 221.3;Neutrophils: 357.3;NK-cells: 358.5;pDCs: 159.7;Plasma cells: 723.3;T-cells: 643.2;Thymocytes: 379.4" "Cell type enriched" "Detected in some" 5 "leukocyte: 344.2" "Cancer enhanced" "Detected in all" "Breast Invasive Carcinoma (TCGA): 24.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Bone cancer: 37.1;Leukemia: 60.8;lymphoma: 89.5;Myeloma: 49.9" "Adipose visceral - T-cells, Adrenal gland - T-cells, Liver - T-cells, Prostate - T-cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA030345, HPA061314" Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 39: Astrocytes - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 15 "Golgi apparatus, Vesicles" "HPA030345: , HPA061314: " "unprognostic (7.47e-2)" "unprognostic (1.64e-1)" "unprognostic (9.69e-2)" "unprognostic (3.58e-3)" "unprognostic (4.72e-2)" "unprognostic (2.13e-2)" "unprognostic (4.93e-2)" "unprognostic (2.10e-1)" "unprognostic (5.12e-3)" "unprognostic (8.94e-2)" "unprognostic (2.00e-1)" "unprognostic (2.53e-1)" "unprognostic (1.26e-3)" "unprognostic (1.60e-1)" "unprognostic (5.69e-2)" "potential prognostic favorable (6.95e-4)" "unprognostic (9.56e-2)" "unprognostic (2.01e-1)" "unprognostic (1.16e-1)" "unprognostic (1.17e-1)" "unprognostic (2.53e-1)" "unprognostic (2.74e-2)" "unprognostic (1.28e-2)" "unprognostic (1.59e-1)" "unprognostic (4.64e-2)" "unprognostic (1.99e-3)" "potential prognostic favorable (1.29e-4)" "unprognostic (2.99e-2)" "unprognostic (1.94e-2)" "unprognostic (1.14e-1)" "unprognostic (2.01e-2)" RHOJ "ARHJ, FLJ14445, RASL7B, TCL" ENSG00000126785 "Ras homolog family member J" Q9H4E5 14 63204114-63293508 "Predicted intracellular proteins" Angiogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 199.1;Bergmann glia: 327.9;Fibro-adipogenic progenitors: 133.4;Lymphatic endothelial cells: 642.8;Melanocytes: 69.8;Myosatellite cells: 111.7;Pericytes: 103.8;Vascular endothelial cells: 236.0" "Cell type enhanced" "Detected in many" "Bergmann glia: 349.5;pericyte: 617.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 20.2;skin cancer: 33.3" "Adrenal gland - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Pancreas - Endothelial cells, Prostate - Fibroblasts, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003050 Uncertain Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 29 "Plasma membrane" "Nucleoplasm, Nucleoli" "HPA003050: " "potential prognostic favorable (3.50e-4)" "unprognostic (2.99e-1)" "unprognostic (1.17e-1)" "unprognostic (2.19e-3)" "unprognostic (5.07e-2)" "unprognostic (6.92e-2)" "unprognostic (2.83e-1)" "unprognostic (1.80e-3)" "unprognostic (3.79e-2)" "unprognostic (8.38e-2)" "validated prognostic favorable (3.59e-4)" "validated prognostic favorable (2.24e-4)" "potential prognostic unfavorable (8.37e-5)" "unprognostic (8.07e-2)" "unprognostic (3.24e-2)" "unprognostic (6.99e-2)" "unprognostic (3.10e-2)" "unprognostic (2.93e-2)" "unprognostic (8.55e-2)" "unprognostic (8.23e-2)" "unprognostic (1.20e-1)" "unprognostic (2.58e-2)" "unprognostic (1.94e-2)" "unprognostic (9.77e-2)" "unprognostic (2.12e-2)" "unprognostic (1.76e-1)" "unprognostic (8.96e-2)" "unprognostic (2.92e-3)" "unprognostic (6.23e-2)" "unprognostic (8.14e-3)" "unprognostic (1.04e-2)" RHOQ "ARHQ, RASL7A, TC10" ENSG00000119729 "Ras homolog family member Q" P17081 2 46541806-46584688 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 169.4" "Low cell type specificity" "Detected in many" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 244.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 1.5;classical monocyte: 2.5;eosinophil: 4.2;intermediate monocyte: 2.7;memory B-cell: 1.8;myeloid DC: 1.6;naive B-cell: 2.4;neutrophil: 4.9;non-classical monocyte: 2.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044938 Approved Vesicles,Cytosol No No "Cluster 2: Dendritic cells - Unknown function" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 19: Astrocytes - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 103: Non-specific - Basic cellular processes" 13 "Vesicles, Cytosol" "HPA044938: " "unprognostic (1.89e-1)" "unprognostic (1.64e-1)" "unprognostic (1.51e-2)" "unprognostic (9.79e-2)" "unprognostic (5.59e-2)" "unprognostic (1.76e-1)" "unprognostic (2.19e-2)" "unprognostic (6.42e-3)" "unprognostic (1.98e-2)" "unprognostic (1.72e-2)" "potential prognostic unfavorable (5.53e-4)" "unprognostic (1.29e-2)" "unprognostic (5.03e-1)" "potential prognostic unfavorable (1.55e-4)" "unprognostic (4.29e-2)" "unprognostic (8.98e-2)" "unprognostic (2.35e-1)" "unprognostic (7.87e-2)" "unprognostic (2.33e-1)" "unprognostic (1.29e-1)" "unprognostic (4.57e-1)" "unprognostic (2.09e-1)" "unprognostic (6.28e-2)" "unprognostic (3.07e-1)" "unprognostic (1.09e-1)" "unprognostic (1.85e-2)" "unprognostic (1.18e-1)" "unprognostic (2.32e-3)" "unprognostic (1.52e-1)" "unprognostic (9.19e-3)" "unprognostic (1.03e-2)" RHOT1 "ARHT1, FLJ11040, MIRO-1, MIRO1" ENSG00000126858 "Ras homolog family member T1" Q8IXI2 17 32142454-32253374 "Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Müller glia: 325.6;Myonuclei: 377.9;Neutrophils: 340.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010687, CAB068223, CAB068224" Supported NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 13 "CAB068223: , CAB068224: , HPA010687: " "unprognostic (2.26e-1)" "unprognostic (1.49e-2)" "unprognostic (2.84e-1)" "unprognostic (3.48e-3)" "unprognostic (1.26e-1)" "unprognostic (2.84e-1)" "unprognostic (1.80e-1)" "unprognostic (2.52e-2)" "unprognostic (6.69e-2)" "unprognostic (2.34e-3)" "potential prognostic favorable (1.76e-4)" "unprognostic (6.90e-2)" "unprognostic (5.55e-2)" "unprognostic (2.51e-2)" "unprognostic (7.95e-3)" "unprognostic (1.85e-1)" "unprognostic (9.99e-2)" "unprognostic (2.87e-1)" "unprognostic (1.31e-1)" "unprognostic (1.74e-2)" "unprognostic (2.29e-2)" "unprognostic (3.36e-2)" "unprognostic (2.77e-3)" "unprognostic (2.80e-1)" "unprognostic (6.60e-2)" "unprognostic (4.54e-2)" "unprognostic (8.09e-3)" "unprognostic (2.78e-2)" "unprognostic (1.34e-1)" "unprognostic (3.37e-1)" "unprognostic (8.82e-2)" RHOT2 "ARHT2, C16orf39, MIRO-2, MIRO2" ENSG00000140983 "Ras homolog family member T2" Q8IXI1 16 668100-674174 "Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 130.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012624, HPA012895" Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 79: Photoreceptor cells - Phototransduction" 41 Mitochondria "HPA012624: , HPA012895: " "unprognostic (1.66e-1)" "unprognostic (4.98e-2)" "unprognostic (2.54e-1)" "unprognostic (1.39e-1)" "unprognostic (9.64e-2)" "unprognostic (7.94e-2)" "unprognostic (1.15e-1)" "unprognostic (2.35e-2)" "unprognostic (1.29e-2)" "unprognostic (2.01e-1)" "unprognostic (2.29e-2)" "unprognostic (1.07e-1)" "potential prognostic favorable (7.08e-7)" "unprognostic (1.47e-3)" "unprognostic (1.31e-1)" "unprognostic (1.56e-1)" "unprognostic (1.94e-2)" "unprognostic (3.91e-3)" "unprognostic (4.83e-2)" "unprognostic (1.01e-1)" "unprognostic (1.31e-2)" "unprognostic (1.60e-1)" "unprognostic (1.23e-3)" "unprognostic (3.95e-1)" "unprognostic (1.80e-2)" "unprognostic (3.10e-1)" "unprognostic (5.78e-3)" "unprognostic (1.70e-1)" "unprognostic (1.40e-1)" "unprognostic (1.34e-2)" "unprognostic (2.02e-1)" RHOU "ARHU, CDC42L1, DJ646B12.2, fJ646B12.2, FLJ10616, hG28K, WRCH-1, WRCH1" ENSG00000116574 "Ras homolog family member U" Q7L0Q8 1 228735479-228746664 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 67.0" "Cell type enriched" "Detected in some" 4 "Oligodendrocytes: 189.0" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 85.1;oligodendrocyte: 231.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049592 Approved Uncertain "Microtubules,Primary cilium" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 34: Testis cancer - Unknown function" "Cluster 80: Oligodendrocytes - Myelination" 15 Microtubules "Primary cilium" "HPA049592: " "unprognostic (8.71e-3)" "unprognostic (8.42e-2)" "unprognostic (1.61e-2)" "unprognostic (1.37e-1)" "unprognostic (1.38e-2)" "unprognostic (1.88e-2)" "unprognostic (7.78e-3)" "unprognostic (4.12e-1)" "unprognostic (1.71e-1)" "unprognostic (2.84e-1)" "validated prognostic favorable (3.22e-8)" "validated prognostic favorable (2.17e-4)" "unprognostic (2.84e-3)" "unprognostic (6.18e-2)" "unprognostic (3.22e-2)" "unprognostic (3.09e-1)" "unprognostic (9.07e-3)" "unprognostic (1.05e-1)" "unprognostic (2.00e-2)" "unprognostic (2.12e-1)" "unprognostic (3.65e-1)" "unprognostic (7.97e-2)" "unprognostic (7.58e-2)" "unprognostic (6.32e-2)" "unprognostic (1.85e-1)" "unprognostic (3.04e-1)" "unprognostic (4.75e-1)" "unprognostic (1.13e-1)" "unprognostic (1.08e-1)" "unprognostic (1.51e-1)" RHOV "ARHV, Chp, WRCH2" ENSG00000104140 "Ras homolog family member V" Q96L33 15 40872214-40874234 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 210.1;skin 1: 129.0;vagina: 92.9" "Cell type enhanced" "Detected in many" "Breast secretory cells: 161.0;Esophageal apical cells: 890.8;Esophageal basal cells: 533.8;Esophageal suprabasal cells: 829.8;Prostatic club cells: 236.0;Submucosal glandular cells: 319.0;Suprabasal keratinocytes: 299.1;Urothelial cells: 158.4" "Cell type enhanced" "Detected in many" "lower rhombic lip: 5.8" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 181.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 134.6" "Lung - Respiratory ciliated cells, Pancreas - Ductal cells, Prostate - Urothelial cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA053343 Enhanced NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 24: Neurons - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 85: Squamous epithelial cells - Keratinization" 3 "HPA053343: " "unprognostic (7.96e-2)" "unprognostic (7.19e-2)" "unprognostic (3.66e-1)" "unprognostic (7.57e-2)" "unprognostic (8.74e-2)" "unprognostic (1.19e-1)" "unprognostic (1.96e-2)" "unprognostic (2.50e-1)" "unprognostic (1.91e-2)" "unprognostic (3.13e-2)" "unprognostic (4.19e-1)" "unprognostic (2.77e-2)" "unprognostic (2.48e-2)" "potential prognostic unfavorable (1.62e-8)" "unprognostic (4.60e-3)" "unprognostic (2.08e-2)" "unprognostic (1.51e-1)" "unprognostic (1.06e-1)" "unprognostic (2.17e-1)" "potential prognostic unfavorable (2.41e-4)" "unprognostic (9.55e-3)" "unprognostic (8.90e-3)" "unprognostic (6.72e-2)" "unprognostic (2.31e-2)" "unprognostic (2.34e-1)" "unprognostic (6.55e-2)" "unprognostic (1.06e-1)" "unprognostic (1.18e-2)" "unprognostic (1.33e-1)" RHOXF1 "OTEX, PEPP1" ENSG00000101883 "Rhox homeobox family member 1" Q8NHV9 X 120109051-120245267 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.3;testis: 15.0" "Cell type enhanced" "Detected in many" "Adipocytes: 58.7;Adrenal cortex cells: 48.3;Differentiating spermatogonia: 150.9;Gonadotrophs: 41.0;Granulosa cells: 69.7;Pituitary stem cells: 48.8;Sertoli cells: 42.0;Undifferentiated spermatogonia: 149.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "T-reg: 4.7" "Lineage enriched" "Detected in single" 32 "T-cells: 4.7" "Not detected" "Not detected" "Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" "HPA052560, HPA056506" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 67: Testis - Mixed function" "Cluster 2: Neurons - Nucleosome" "Cluster 59: Leukemia - T-cell receptor" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 1 Nucleoplasm Cytosol "HPA052560: , HPA056506: " "unprognostic (3.74e-2)" "unprognostic (2.01e-1)" "unprognostic (1.69e-1)" "unprognostic (1.35e-1)" RHOXF1P3 ENSG00000282933 "Rhox homeobox family member 1 pseudogene 3" X 119942834-119992838 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 39 "pancreas: 31.4" "Cell type enhanced" "Detected in many" "Adipocytes: 15.8;Cardiomyocytes: 47.3;Epicardial cells: 22.7;Sertoli cells: 9.8;Undifferentiated spermatogonia: 16.0" "Low cell type specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 7 "basophil: 38.1;eosinophil: 49.6" "Lineage enriched" "Detected in all" 8 "granulocytes: 49.6" "Cancer enhanced" "Detected in some" "Neuroblastoma: 4.4" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 8: Pancreas - Proteolysis" "Cluster 11: White matter - Signal transduction" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" RHOXF2 "CT107, PEPP-2, PEPP2, THG1" ENSG00000131721 "Rhox homeobox family member 2" Q9BQY4 X 120158613-120165630 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 15 "testis: 3.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 5.8;Differentiating spermatogonia: 1.4;Epicardial cells: 2.3;Undifferentiated spermatogonia: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Leukemia: 3.9;Myeloma: 10.9" "Testis - Spermatogonia" "HPA003314, CAB020794" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 70 "Plasma membrane" Nucleoplasm "CAB020794: , HPA003314: " RHOXF2B ENSG00000203989 "Rhox homeobox family member 2B" P0C7M4 X 120072264-120077690 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 119 "testis: 28.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 7.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Gastric cancer: 17.4;Leukemia: 33.6;Myeloma: 37.2" HPA003314 Supported Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 106: Spermatogonia - Spermatogonial differentiation" "Plasma membrane" Nucleoplasm "HPA003314: " "unprognostic (1.39e-2)" "potential prognostic unfavorable (6.50e-4)" "unprognostic (1.92e-1)" RHPN1 "KIAA1929, ODF5, RHPN" ENSG00000158106 "Rhophilin Rho GTPase binding protein 1" Q8TCX5 8 143368876-143384221 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.0;pituitary gland: 18.9;thyroid gland: 19.4" "Cell type enhanced" "Detected in many" "Astrocytes: 72.4;Ependymal cells: 46.6;Epididymal efferent duct ciliated cells: 39.5;Fallopian tube ciliated cells: 49.8;Proximal tubule cells: 39.9;Respiratory ciliated cells: 68.0" "Cell type enhanced" "Detected in all" "astrocyte: 102.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Breast - Breast glandular cells, Liver - Vascular endothelial cells, Lung - Respiratory ciliated cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA024288, HPA024671" Approved Approved Nucleoplasm NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 29: Forebrain - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 28: Astrocytes - Homeostasis & neuron support" 19 Nucleoplasm "HPA024288: , HPA024671: " "unprognostic (6.32e-2)" "unprognostic (1.64e-2)" "unprognostic (2.56e-1)" "unprognostic (3.13e-3)" "unprognostic (2.76e-1)" "unprognostic (7.02e-2)" "unprognostic (4.79e-2)" "unprognostic (3.30e-1)" "unprognostic (1.04e-1)" "unprognostic (2.24e-1)" "unprognostic (5.33e-2)" "unprognostic (2.78e-1)" "unprognostic (2.58e-2)" "unprognostic (4.01e-3)" "unprognostic (5.12e-2)" "unprognostic (2.34e-2)" "unprognostic (1.79e-1)" "potential prognostic unfavorable (9.47e-4)" "unprognostic (2.61e-1)" "unprognostic (1.72e-3)" "unprognostic (2.37e-2)" "unprognostic (1.69e-3)" "unprognostic (2.71e-1)" "unprognostic (2.21e-1)" "unprognostic (5.14e-1)" "unprognostic (1.24e-2)" "unprognostic (1.74e-2)" "unprognostic (5.54e-2)" "unprognostic (2.51e-1)" "unprognostic (7.68e-2)" RHPN2 ENSG00000131941 "Rhophilin Rho GTPase binding protein 2" Q8IUC4 19 32978592-33064888 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Colonocytes: 436.6;Endometrial ciliated cells: 351.0;Endometrial glandular cells: 444.7;Endometrial luminal cells: 391.3;Enteric stem cells: 315.6;Enteric transient amplifying cells: 291.6;Enterocytes: 338.0;Foveolar cells: 503.0;Prostatic glandular cells: 354.7;Urothelial cells: 249.9" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 54.0;ependymal cell: 47.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051749 Uncertain NA NA "Cluster 77: Intestine - Digestion" "Cluster 44: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 51: Secretory epithelial cells - Mixed function" 8 "HPA051749: " "unprognostic (2.47e-3)" "unprognostic (2.10e-1)" "unprognostic (4.56e-1)" "unprognostic (2.14e-2)" "unprognostic (5.85e-3)" "unprognostic (1.53e-1)" "unprognostic (3.25e-1)" "potential prognostic unfavorable (2.25e-4)" "potential prognostic unfavorable (2.97e-5)" "unprognostic (1.08e-2)" "potential prognostic favorable (1.15e-10)" "unprognostic (1.20e-2)" "unprognostic (1.68e-1)" "unprognostic (2.00e-2)" "unprognostic (1.07e-2)" "unprognostic (1.03e-3)" "unprognostic (1.55e-2)" "unprognostic (7.14e-2)" "unprognostic (3.96e-1)" "potential prognostic unfavorable (9.88e-4)" "unprognostic (1.52e-1)" "unprognostic (8.99e-3)" "unprognostic (8.26e-2)" "unprognostic (2.84e-1)" "unprognostic (1.42e-2)" "unprognostic (2.11e-1)" "unprognostic (1.17e-1)" "unprognostic (6.75e-2)" "unprognostic (1.06e-1)" "unprognostic (4.58e-2)" "unprognostic (7.29e-2)" RIBC1 FLJ32783 ENSG00000158423 "RIB43A domain with coiled-coils 1" Q8N443 X 53422690-53431120 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 26.6;fallopian tube: 25.8;testis: 35.4" "Cell type enhanced" "Detected in many" "Early spermatids: 273.7;Endometrial ciliated cells: 79.0;Epididymal efferent duct ciliated cells: 66.7;Fallopian tube ciliated cells: 173.6;Late primary spermatocytes: 104.8;Late spermatids: 993.9;Respiratory ciliated cells: 130.2" "Group enriched" "Detected in some" 6 "choroid plexus epithelial cell: 8.5;ependymal cell: 33.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Testis - Late spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA001150 Approved "Nuclear bodies" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 27: Breast cancer - Unknown function" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 45 "Nuclear bodies" "HPA001150: " "unprognostic (4.85e-3)" "unprognostic (6.52e-2)" "unprognostic (1.38e-1)" "potential prognostic favorable (5.32e-4)" "unprognostic (7.19e-2)" "unprognostic (1.32e-1)" "unprognostic (1.17e-1)" "unprognostic (2.00e-2)" "unprognostic (7.48e-3)" "unprognostic (5.50e-2)" "unprognostic (8.33e-2)" "unprognostic (6.20e-2)" "unprognostic (3.70e-2)" "unprognostic (1.83e-1)" "unprognostic (1.83e-2)" "potential prognostic favorable (8.31e-4)" "unprognostic (1.97e-2)" "unprognostic (3.71e-3)" "unprognostic (2.31e-2)" "unprognostic (3.15e-1)" "unprognostic (4.38e-2)" "unprognostic (1.79e-1)" "unprognostic (2.66e-1)" "unprognostic (8.98e-2)" "unprognostic (1.22e-1)" "unprognostic (1.79e-1)" "unprognostic (7.85e-2)" "unprognostic (1.60e-1)" RIBC2 "C22orf11, DKFZp566F0546, FLJ25720" ENSG00000128408 "RIB43A domain with coiled-coils 2" Q9H4K1 22 45413693-45432509 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "choroid plexus: 12.6;fallopian tube: 9.2;testis: 28.8" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 53.3;Differentiating spermatogonia: 43.9;Early primary spermatocytes: 56.6;Early spermatids: 169.1;Endometrial ciliated cells: 98.5;Ependymal cells: 47.5;Epididymal efferent duct ciliated cells: 89.8;Fallopian tube ciliated cells: 92.9;Late primary spermatocytes: 381.5;Respiratory ciliated cells: 110.2;Respiratory deuterosomal cells: 79.8" "Group enriched" "Detected in many" 21 "choroid plexus epithelial cell: 41.2;ependymal cell: 54.4" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 10.5" "Region enriched" "Detected in all" 5 "choroid plexus: 30.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Not detected" "Not detected" "Region enhanced" "Detected in many" "midbrain: 22.1" HPA003210 Approved Approved "Perinuclear theca,Calyx,Connecting piece,Mid piece,Principal piece,End piece" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" 3 "Connecting piece, Mid piece, Principal piece, End piece" "Perinuclear theca, Calyx" "HPA003210: " "unprognostic (5.91e-3)" "unprognostic (5.95e-2)" "unprognostic (7.94e-2)" "unprognostic (1.06e-3)" "unprognostic (3.17e-1)" "unprognostic (1.92e-2)" "unprognostic (1.80e-1)" "unprognostic (2.94e-2)" "unprognostic (8.59e-3)" "unprognostic (1.94e-2)" "unprognostic (8.97e-3)" "unprognostic (9.04e-2)" "unprognostic (7.20e-2)" "unprognostic (2.47e-1)" "potential prognostic favorable (5.99e-4)" "unprognostic (4.90e-2)" "unprognostic (3.85e-1)" "unprognostic (5.03e-2)" "unprognostic (9.52e-2)" "unprognostic (3.12e-1)" "unprognostic (1.98e-1)" "unprognostic (1.35e-1)" RIC1 "bA207C16.1, KIAA1432" ENSG00000107036 "RIC1 homolog, RAB6A GEF complex partner 1" Q4ADV7 9 5629025-5776557 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Guanine-nucleotide releasing factor" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051578 Supported NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 47: Leukemia - Hemostasis" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 5 "HPA051578: " "unprognostic (2.90e-2)" "unprognostic (2.24e-1)" "unprognostic (2.91e-3)" "unprognostic (6.96e-2)" "potential prognostic unfavorable (4.94e-5)" "unprognostic (1.47e-1)" "unprognostic (4.19e-1)" "unprognostic (4.45e-2)" "unprognostic (2.28e-2)" "potential prognostic favorable (8.56e-4)" "unprognostic (9.87e-2)" "unprognostic (1.68e-1)" "unprognostic (6.72e-3)" "unprognostic (1.19e-1)" "unprognostic (1.12e-2)" "unprognostic (3.23e-2)" "unprognostic (9.63e-2)" "unprognostic (1.07e-1)" "unprognostic (5.53e-1)" "unprognostic (1.90e-2)" "unprognostic (5.01e-3)" "unprognostic (1.93e-3)" "unprognostic (3.20e-3)" "unprognostic (3.77e-2)" "unprognostic (2.87e-2)" "unprognostic (6.75e-2)" "unprognostic (1.90e-1)" "unprognostic (6.12e-2)" "unprognostic (3.35e-2)" RIC3 "AYST720, FLJ11608, PRO1385" ENSG00000166405 "RIC3 acetylcholine receptor chaperone" Q7Z5B4 11 8106056-8169055 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 201.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 5 "B-cells: 12.8;granulocytes: 3.7;T-cells: 6.6" "Cancer enhanced" "Detected in some" "Neuroblastoma: 5.6;prostate cancer: 4.0;testis cancer: 4.0" "Adipose visceral - Mesothelial cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065016 Approved "Intracellular and membrane" Other NA NA "Cluster 24: Non-specific - Transcription" "Cluster 65: Brain - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" "HPA065016: " "potential prognostic favorable (6.40e-4)" "unprognostic (5.70e-2)" "unprognostic (2.18e-2)" "unprognostic (2.22e-1)" "unprognostic (1.93e-1)" "unprognostic (2.65e-3)" "unprognostic (1.47e-3)" "potential prognostic favorable (5.83e-4)" "potential prognostic favorable (1.50e-4)" "unprognostic (1.07e-1)" "unprognostic (2.41e-2)" "unprognostic (1.17e-1)" "unprognostic (7.36e-2)" "unprognostic (3.85e-1)" "potential prognostic favorable (4.40e-4)" "unprognostic (5.03e-3)" "unprognostic (4.05e-1)" "unprognostic (3.65e-2)" "unprognostic (5.07e-2)" "unprognostic (8.73e-2)" RIC8A "synembryn, synembryn-A" ENSG00000177963 "RIC8 guanine nucleotide exchange factor A" Q9NPQ8 11 207708-215113 "Predicted intracellular proteins" "Chaperone, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 92.1;Late primary spermatocytes: 96.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041491, CAB046012" Approved Approved "Plasma membrane,Cytosol" NA NA 20000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 51: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 24 Cytosol "Plasma membrane" "CAB046012: , HPA041491: " "unprognostic (1.18e-1)" "unprognostic (2.31e-1)" "potential prognostic unfavorable (8.56e-4)" "unprognostic (5.47e-3)" "unprognostic (1.85e-1)" "unprognostic (1.20e-3)" "unprognostic (1.71e-3)" "unprognostic (1.18e-3)" "unprognostic (1.08e-1)" "unprognostic (1.00e-2)" "unprognostic (1.17e-2)" "unprognostic (2.66e-2)" "unprognostic (7.35e-2)" "potential prognostic unfavorable (1.99e-8)" "unprognostic (4.13e-2)" "unprognostic (1.58e-2)" "unprognostic (4.12e-3)" "unprognostic (3.72e-2)" "unprognostic (1.10e-1)" "unprognostic (1.41e-1)" "unprognostic (7.51e-2)" "unprognostic (2.05e-1)" "unprognostic (6.61e-3)" "unprognostic (2.81e-1)" "unprognostic (9.55e-2)" "unprognostic (2.23e-1)" "unprognostic (2.33e-1)" "unprognostic (2.65e-1)" "unprognostic (1.22e-1)" "unprognostic (9.82e-2)" "unprognostic (1.62e-1)" RIC8B "FLJ10620, hSyn, RIC8" ENSG00000111785 "RIC8 guanine nucleotide exchange factor B" Q9NVN3 12 106774621-106889316 "Predicted intracellular proteins" "Chaperone, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 320.0;Choroid plexus epithelial cells: 201.0" "Cell type enhanced" "Detected in all" "medium spiny neuron: 724.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039970, HPA042746" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 65: Brain - Transcription" "Cluster 33: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 35: Neurons - Synaptic function & neurogenesis" 2 Cytosol "Plasma membrane" "HPA039970: , HPA042746: " "unprognostic (7.26e-2)" "unprognostic (1.04e-1)" "unprognostic (3.47e-2)" "unprognostic (9.08e-2)" "unprognostic (5.89e-2)" "unprognostic (3.20e-2)" "unprognostic (2.32e-1)" "unprognostic (8.07e-2)" "unprognostic (5.24e-2)" "unprognostic (2.87e-2)" "potential prognostic favorable (6.56e-6)" "unprognostic (7.29e-3)" "unprognostic (2.14e-1)" "unprognostic (1.11e-1)" "unprognostic (8.26e-2)" "unprognostic (5.57e-2)" "unprognostic (1.75e-1)" "unprognostic (1.41e-1)" "unprognostic (1.36e-1)" "unprognostic (1.37e-1)" "unprognostic (1.12e-1)" "unprognostic (4.44e-3)" "unprognostic (5.91e-2)" "unprognostic (4.46e-2)" "unprognostic (5.97e-2)" "unprognostic (1.92e-1)" "unprognostic (2.30e-1)" "unprognostic (1.83e-1)" "unprognostic (4.07e-2)" "unprognostic (1.45e-1)" "unprognostic (1.30e-1)" RICTOR "AVO3, KIAA1999, MGC39830, PIA" ENSG00000164327 "RPTOR independent companion of MTOR complex 2" Q6R327 5 38937920-39074399 "Essential proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 1005.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 30.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 30.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037802, HPA037803" Approved Approved Mitochondria NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 40: Non-specific - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 29: Non-specific - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" 102 Mitochondria "HPA037802: , HPA037803: " "unprognostic (4.17e-1)" "unprognostic (6.70e-2)" "unprognostic (5.28e-1)" "unprognostic (5.23e-2)" "unprognostic (5.05e-2)" "unprognostic (5.14e-2)" "unprognostic (3.01e-1)" "unprognostic (2.02e-3)" "unprognostic (2.24e-2)" "unprognostic (1.71e-2)" "potential prognostic favorable (9.54e-4)" "unprognostic (6.74e-3)" "unprognostic (9.46e-2)" "unprognostic (1.09e-3)" "unprognostic (2.48e-1)" "unprognostic (2.37e-1)" "unprognostic (1.05e-2)" "unprognostic (1.45e-1)" "unprognostic (2.62e-1)" "unprognostic (4.46e-2)" "unprognostic (4.56e-2)" "unprognostic (4.23e-3)" "potential prognostic unfavorable (1.58e-4)" "unprognostic (1.44e-1)" "unprognostic (5.75e-3)" "unprognostic (3.39e-2)" "unprognostic (3.18e-1)" "unprognostic (1.86e-1)" "unprognostic (3.23e-1)" "unprognostic (4.08e-2)" "unprognostic (6.02e-2)" RIDA "HRSP12, P14.5, PSP, UK114" ENSG00000132541 "Reactive intermediate imine deaminase A homolog" P52758 8 98102344-98117171 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "kidney: 462.4;liver: 1435.3" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 954.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 344.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022856, HPA023489" Enhanced NA NA 2200000 "Cluster 33: Non-specific - ATP binding" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 1 "HPA022856: , HPA023489: " "unprognostic (3.81e-2)" "unprognostic (3.80e-3)" "unprognostic (2.43e-1)" "unprognostic (2.75e-1)" "unprognostic (6.72e-3)" "unprognostic (3.78e-1)" "unprognostic (2.90e-1)" "unprognostic (2.15e-2)" "unprognostic (4.36e-2)" "potential prognostic favorable (3.42e-5)" "unprognostic (6.03e-2)" "unprognostic (3.97e-3)" "potential prognostic favorable (2.38e-4)" "unprognostic (7.19e-3)" "unprognostic (1.95e-1)" "unprognostic (1.97e-1)" "unprognostic (4.29e-1)" "unprognostic (1.43e-1)" "unprognostic (1.32e-1)" "unprognostic (1.80e-1)" "unprognostic (9.27e-3)" "unprognostic (3.64e-1)" "potential prognostic favorable (7.96e-4)" "unprognostic (3.09e-1)" "unprognostic (1.11e-1)" "unprognostic (4.12e-1)" "unprognostic (2.72e-1)" "unprognostic (7.62e-2)" "unprognostic (1.65e-1)" RIF1 "FLJ10599, FLJ12870" ENSG00000080345 "Replication timing regulatory factor 1" Q5UIP0 2 151409883-151508013 "Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 8 "Myonuclei: 3994.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036887, HPA036888" Supported Supported "Nucleoplasm,Nuclear membrane,Plasma membrane" No No "Cluster 35: Neutrophils - Protein binding" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 39 Nucleoplasm "Nuclear membrane, Plasma membrane" "HPA036887: , HPA036888: " "unprognostic (1.66e-1)" "unprognostic (1.39e-1)" "unprognostic (7.42e-2)" "unprognostic (6.55e-2)" "unprognostic (6.43e-2)" "unprognostic (9.86e-2)" "unprognostic (1.41e-1)" "unprognostic (7.73e-2)" "unprognostic (1.31e-1)" "potential prognostic unfavorable (2.73e-4)" "potential prognostic favorable (1.71e-4)" "unprognostic (4.69e-3)" "unprognostic (1.09e-1)" "unprognostic (5.69e-2)" "unprognostic (2.51e-2)" "unprognostic (9.82e-3)" "unprognostic (2.05e-2)" "unprognostic (1.79e-2)" "unprognostic (9.48e-2)" "unprognostic (1.89e-1)" "unprognostic (1.31e-2)" "potential prognostic unfavorable (8.79e-4)" "unprognostic (1.21e-3)" "unprognostic (6.27e-2)" "unprognostic (1.21e-1)" "unprognostic (1.01e-2)" "unprognostic (3.19e-2)" "unprognostic (2.07e-1)" "unprognostic (7.72e-2)" "unprognostic (1.25e-2)" "unprognostic (1.70e-1)" RIGI "DDX58, DKFZp434J1111, FLJ13599, RIG-1, RIG-I, RIG1" ENSG00000107201 "RNA sensor RIG-I" O95786 9 32455302-32526208 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" "Helicase, Hydrolase, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 37.2;Bergmann glia: 34.6;Brain excitatory neurons: 21.1;Brain inhibitory neurons: 19.0;Choroid plexus epithelial cells: 35.6;Distal convoluted tubule cells: 24.7;Ependymal cells: 32.4;Loop of henle epithelial cells: 32.9;Microglia: 62.3;Oligodendrocyte progenitor cells: 46.0;Oligodendrocytes: 26.3;Other brain neurons: 34.3;Papillary tip epithelial cells: 36.3;Podocytes: 31.2;Proximal tubule cells: 47.0;Renal collecting duct intercalated cells: 27.8;Renal collecting duct principal cells: 41.1;Renal connecting tubule cells: 27.1" "Cell type enhanced" "Detected in all" "endothelial cell: 162.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB012643, HPA047193, HPA073217" Approved Supported "Plasma membrane,Cytosol" No No "Cluster 24: Non-specific - Transcription" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 102: Non-specific - Mixed function" 47 "Plasma membrane, Cytosol" "CAB012643: , HPA047193: , HPA073217: " "unprognostic (6.06e-2)" "unprognostic (3.45e-1)" "unprognostic (1.40e-1)" "unprognostic (2.52e-1)" "unprognostic (9.67e-2)" "unprognostic (2.64e-1)" "unprognostic (1.95e-1)" "unprognostic (1.42e-1)" "unprognostic (8.33e-2)" "unprognostic (1.57e-1)" "potential prognostic favorable (1.20e-4)" "unprognostic (4.02e-2)" "unprognostic (2.50e-1)" "unprognostic (6.67e-2)" "unprognostic (1.33e-2)" "unprognostic (4.34e-2)" "unprognostic (7.43e-2)" "unprognostic (2.53e-1)" "unprognostic (3.71e-2)" "unprognostic (1.43e-2)" "unprognostic (7.97e-2)" "unprognostic (4.46e-3)" "unprognostic (2.18e-3)" "unprognostic (2.94e-1)" "unprognostic (1.03e-1)" "unprognostic (1.11e-3)" "unprognostic (1.25e-1)" "unprognostic (2.78e-3)" "unprognostic (4.11e-2)" "unprognostic (1.27e-2)" "unprognostic (1.47e-2)" RIIAD1 "C1orf230, FLJ36032, NCRNA00166" ENSG00000178796 "Regulatory subunit of type II PKA R-subunit domain containing 1" A6NNX1 1 151710433-151729805 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 23.4;pituitary gland: 13.0;testis: 8.4" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 80.7;Early spermatids: 64.7;Endometrial ciliated cells: 151.1;Epididymal efferent duct ciliated cells: 230.0;Fallopian tube ciliated cells: 272.8;Late primary spermatocytes: 108.2;Late spermatids: 72.1;Neuroendocrine cells: 43.3;Oocytes: 55.3;Respiratory ciliated cells: 236.3" "Cell type enhanced" "Detected in many" "ependymal cell: 33.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 11 "Neuroblastoma: 7.4" "Adrenal gland - Adrenal medulla cells, Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045703 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 33: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 107: Ciliated cells - Cilia assembly & function" Cytosol Nucleoplasm "HPA045703: " "unprognostic (3.01e-1)" "unprognostic (1.22e-3)" "unprognostic (2.04e-3)" "unprognostic (7.18e-2)" "unprognostic (6.22e-3)" "unprognostic (4.19e-3)" "unprognostic (1.10e-1)" "unprognostic (8.49e-2)" "unprognostic (1.06e-1)" RILP FLJ31193 ENSG00000167705 "Rab interacting lysosomal protein" Q96NA2 17 1646145-1649866 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 65.2;skeletal muscle: 52.4" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 8.3;Distal convoluted tubule cells: 10.6;Foveolar cells: 4.7;Kupffer cells: 5.1;Loop of henle epithelial cells: 5.5;Other brain neurons: 5.4;Proximal tubule cells: 6.6;Renal collecting duct intercalated cells: 13.5;Renal connecting tubule cells: 7.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 3.5;eosinophil: 1.0;intermediate monocyte: 1.2;myeloid DC: 2.4;neutrophil: 3.4;plasmacytoid DC: 1.3" "Group enriched" "Detected in many" 6 "dendritic cells: 2.4;granulocytes: 3.4;monocytes: 3.5" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Stomach - Gastric mucous cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" NA NA 9000 "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 98: Neurons - Neurotransmission & signaling" 10 "unprognostic (2.22e-1)" "potential prognostic favorable (3.98e-4)" "unprognostic (5.46e-2)" "unprognostic (1.24e-2)" "unprognostic (2.75e-1)" "unprognostic (1.55e-2)" "unprognostic (5.55e-2)" "unprognostic (6.56e-3)" "unprognostic (7.27e-2)" "potential prognostic favorable (1.87e-4)" "unprognostic (1.32e-3)" "unprognostic (8.39e-2)" "unprognostic (1.43e-1)" "unprognostic (5.76e-3)" "unprognostic (3.71e-3)" "unprognostic (1.46e-1)" "unprognostic (1.71e-1)" "unprognostic (1.38e-2)" "unprognostic (1.30e-1)" "unprognostic (5.86e-2)" "unprognostic (2.04e-1)" "unprognostic (7.97e-3)" "unprognostic (3.27e-2)" "unprognostic (1.24e-1)" "unprognostic (6.20e-2)" "unprognostic (1.94e-1)" "unprognostic (4.72e-1)" "unprognostic (8.49e-2)" "unprognostic (3.70e-1)" "unprognostic (2.38e-2)" RILPL1 FLJ39378 ENSG00000188026 "Rab interacting lysosomal protein like 1" Q5EBL4 12 123470054-123533719 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 59.0;skeletal muscle: 83.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 141.4;Choroid plexus epithelial cells: 242.1;Myonuclei: 354.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041314 Approved Approved "Nucleoplasm,Plasma membrane,Primary cilium,Centrosome,Basal body,Cytosol" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 11: White matter - Signal transduction" "Cluster 5: Rhabdoid - Unknown function" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 1 "Plasma membrane, Primary cilium, Cytosol" "Nucleoplasm, Centrosome, Basal body" "HPA041314: " "unprognostic (1.48e-1)" "unprognostic (2.60e-1)" "unprognostic (1.79e-1)" "unprognostic (2.43e-2)" "unprognostic (2.28e-1)" "unprognostic (4.83e-3)" "unprognostic (1.31e-1)" "unprognostic (1.40e-1)" "potential prognostic unfavorable (5.84e-4)" "unprognostic (4.77e-2)" "unprognostic (1.53e-2)" "unprognostic (1.00e-1)" "unprognostic (3.28e-2)" "unprognostic (2.17e-2)" "unprognostic (6.38e-2)" "unprognostic (9.28e-2)" "unprognostic (1.43e-1)" "unprognostic (1.26e-1)" "unprognostic (1.21e-1)" "unprognostic (1.47e-1)" "unprognostic (8.14e-2)" "unprognostic (7.50e-2)" "unprognostic (1.26e-1)" "unprognostic (2.18e-1)" "unprognostic (7.75e-2)" "unprognostic (4.13e-3)" "unprognostic (1.53e-1)" "unprognostic (1.32e-1)" "unprognostic (1.42e-1)" "unprognostic (1.48e-2)" "unprognostic (6.27e-2)" RILPL2 "FLJ30380, FLJ32372, MGC7036" ENSG00000150977 "Rab interacting lysosomal protein like 2" Q969X0 12 123415039-123436684 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 109.8" "Cell type enriched" "Detected in many" 4 "Neutrophils: 3537.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Leukemia: 73.1" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028958 Approved Supported "Vesicles,Primary cilium,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 15: Bone marrow - Innate immune response" "Cluster 8: Immune cells - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 2 Cytosol "Vesicles, Primary cilium" "HPA028958: " "unprognostic (1.92e-1)" "unprognostic (1.37e-3)" "unprognostic (1.72e-1)" "unprognostic (8.22e-3)" "unprognostic (1.45e-2)" "unprognostic (3.59e-1)" "unprognostic (2.79e-2)" "unprognostic (9.93e-3)" "unprognostic (2.08e-1)" "unprognostic (7.17e-2)" "potential prognostic favorable (1.20e-7)" "unprognostic (3.20e-3)" "potential prognostic favorable (2.47e-4)" "unprognostic (2.92e-1)" "unprognostic (1.52e-1)" "unprognostic (1.03e-3)" "unprognostic (2.06e-1)" "unprognostic (9.77e-2)" "unprognostic (2.23e-2)" "unprognostic (1.31e-1)" "unprognostic (9.38e-2)" "unprognostic (4.46e-1)" "unprognostic (2.42e-3)" "unprognostic (2.27e-2)" "unprognostic (1.50e-1)" "unprognostic (1.79e-1)" "unprognostic (1.02e-1)" "unprognostic (2.51e-1)" "unprognostic (1.32e-2)" "unprognostic (5.14e-2)" "potential prognostic favorable (3.01e-4)" RIMBP2 "KIAA0318, MGC15831, PPP1R133, RBP2, RIM-BP2" ENSG00000060709 "RIMS binding protein 2" O15034 12 130396133-130768228 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.7;parathyroid gland: 21.3;pituitary gland: 27.5" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 308.5;Choroid plexus epithelial cells: 453.9;Cone photoreceptor cells: 250.5;Corticotrophs: 205.5;Gonadotrophs: 274.7;Lactotrophs: 857.7;Neuroendocrine cells: 475.4;Pancreatic islet cells: 234.4;Somatotrophs: 1601.4;Thyrotrophs: 526.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "Neuroblastoma: 42.6" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Skin - Outer root sheath cells, Stomach - Gastric enteroendocrine cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041494, HPA044114" Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 14: Neurons - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" Nucleoplasm "Golgi apparatus, Cytosol" "HPA041494: , HPA044114: " "unprognostic (1.16e-2)" "unprognostic (3.18e-1)" "unprognostic (2.37e-2)" "unprognostic (5.21e-2)" "unprognostic (2.74e-1)" "unprognostic (1.55e-1)" "unprognostic (6.71e-2)" "unprognostic (1.43e-2)" "unprognostic (1.23e-1)" "unprognostic (1.13e-2)" "unprognostic (1.36e-1)" "potential prognostic favorable (2.75e-4)" "unprognostic (4.33e-1)" "unprognostic (4.68e-1)" "unprognostic (3.91e-2)" "unprognostic (1.35e-2)" "unprognostic (3.95e-1)" "unprognostic (1.50e-1)" "unprognostic (2.74e-1)" RIMBP3 "KIAA1666, RIMBP3.1, RIMBP3A" ENSG00000275793 "RIMS binding protein 3" Q9UFD9 22 18605815-18611919 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 28 "testis: 27.6" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Colon Adenocarcinoma (TCGA): 12.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Testis - Early spermatids, Testis - Late spermatids" HPA001183 Supported Uncertain "Vesicles,Plasma membrane" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 6: Leukemia - Signal transduction" "Cluster 82: Dendritic cells - Antigen presentation" 26 "Vesicles, Plasma membrane" "HPA001183: " "unprognostic (4.64e-2)" "unprognostic (2.02e-2)" "unprognostic (9.17e-2)" "unprognostic (2.32e-1)" "unprognostic (5.45e-3)" "unprognostic (1.08e-2)" "unprognostic (2.90e-1)" "unprognostic (5.52e-2)" "unprognostic (1.11e-3)" RIMBP3B ENSG00000274600 "RIMS binding protein 3B" A6NNM3 22 21383751-21389478 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 28 "testis: 15.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Colon Adenocarcinoma (TCGA): 11.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" HPA001183 Supported Uncertain "Vesicles,Plasma membrane" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 41: Non-specific - Nucleosome assembly" "Vesicles, Plasma membrane" "HPA001183: " "unprognostic (3.63e-2)" "unprognostic (3.96e-1)" "unprognostic (8.25e-2)" "unprognostic (3.91e-2)" "unprognostic (2.16e-1)" "unprognostic (5.40e-3)" "potential prognostic favorable (4.16e-4)" "unprognostic (1.59e-1)" RIMBP3C ENSG00000183246 "RIMS binding protein 3C" A6NJZ7 22 21545666-21551461 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 26 "testis: 6.7" "Group enriched" "Detected in some" 38 "Early spermatids: 27.9;Late primary spermatocytes: 42.8;Late spermatids: 78.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" HPA001183 Supported Uncertain "Vesicles,Plasma membrane" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 35: RS4;11 - Unknown function" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" "Vesicles, Plasma membrane" "HPA001183: " "unprognostic (2.26e-2)" RIMKLA "FAM80A, MGC47816, NAAGS-II, RP11-157D18.1" ENSG00000177181 "Ribosomal modification protein rimK like family member A" Q8IXN7 1 42380792-42424232 "Enzymes, Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 7.9;retina: 10.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 80.4;Brain excitatory neurons: 42.2;Brain inhibitory neurons: 44.7;Colonocytes: 41.0;Cone photoreceptor cells: 64.2;Extravillous trophoblasts: 34.2;Oocytes: 179.6;Other brain neurons: 45.7;Retinal amacrine cells: 43.1;Retinal bipolar cells: 37.2;Retinal ganglion cells: 42.5;Retinal horizontal cells: 62.1;Rod photoreceptor cells: 55.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027826 Uncertain Uncertain "Nucleoli fibrillar center" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 4 "Nucleoli fibrillar center" "HPA027826: " "unprognostic (1.16e-1)" "unprognostic (3.18e-3)" "unprognostic (1.78e-1)" "unprognostic (4.22e-1)" "unprognostic (8.12e-2)" "unprognostic (2.63e-3)" "unprognostic (4.94e-2)" "unprognostic (3.02e-1)" "validated prognostic favorable (7.11e-12)" "validated prognostic favorable (2.93e-8)" "unprognostic (1.53e-1)" "potential prognostic favorable (9.24e-4)" "unprognostic (1.11e-1)" "unprognostic (1.21e-2)" "unprognostic (1.38e-2)" "unprognostic (5.07e-1)" "unprognostic (7.33e-2)" "unprognostic (5.40e-2)" "potential prognostic favorable (6.99e-4)" "unprognostic (2.23e-1)" "unprognostic (7.64e-3)" "unprognostic (1.73e-3)" "unprognostic (1.93e-1)" "unprognostic (1.22e-1)" "unprognostic (3.03e-1)" RIMKLB "FAM80B, KIAA1238, NAAGS, NAAGS-I" ENSG00000166532 "Ribosomal modification protein rimK like family member B" Q9ULI2 12 8681600-8783095 "Enzymes, Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Endometrial glandular cells: 5303.4;Endometrial luminal cells: 1415.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 56.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059552 Approved "Nucleoplasm,Centriolar satellite" NA NA "Cluster 32: Basophils - Transcription" "Cluster 74: Non-specific - Signal transduction" "Cluster 44: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 51: Secretory epithelial cells - Mixed function" "Nucleoplasm, Centriolar satellite" "HPA059552: " "unprognostic (7.10e-2)" "unprognostic (1.10e-1)" "unprognostic (1.45e-1)" "unprognostic (4.23e-2)" "unprognostic (1.65e-3)" "unprognostic (1.52e-1)" "unprognostic (1.21e-1)" "unprognostic (1.21e-2)" "unprognostic (2.80e-2)" "unprognostic (1.21e-1)" "unprognostic (1.93e-1)" "unprognostic (1.19e-2)" "unprognostic (4.56e-3)" "unprognostic (2.31e-2)" "unprognostic (5.63e-2)" "unprognostic (1.35e-2)" "unprognostic (2.14e-1)" "unprognostic (1.82e-1)" "unprognostic (6.14e-2)" "unprognostic (1.08e-2)" "unprognostic (1.40e-1)" "potential prognostic unfavorable (1.11e-4)" "unprognostic (1.03e-1)" "unprognostic (3.89e-2)" "unprognostic (2.29e-2)" "unprognostic (2.16e-2)" "unprognostic (2.71e-2)" "unprognostic (3.47e-1)" "unprognostic (1.21e-1)" "unprognostic (7.57e-2)" RIMOC1 "C5orf51, LOC285636" ENSG00000205765 "RAB7A interacting MON1-CCZ1 complex subunit 1" A6NDU8 5 41904188-41921636 "Predicted intracellular proteins" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 26.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043779, HPA063816" Uncertain Enhanced Nucleoplasm,Cytosol NA NA "Cluster 41: Basophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 29: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 3 Nucleoplasm Cytosol "HPA043779: , HPA063816: " "unprognostic (6.51e-3)" "unprognostic (8.42e-2)" "unprognostic (1.83e-1)" "unprognostic (1.51e-2)" "unprognostic (2.06e-2)" "unprognostic (1.11e-1)" "unprognostic (1.96e-1)" "unprognostic (1.35e-2)" "unprognostic (2.42e-1)" "potential prognostic unfavorable (1.27e-4)" "potential prognostic favorable (2.01e-6)" "unprognostic (6.71e-2)" "unprognostic (3.62e-1)" "potential prognostic unfavorable (8.05e-4)" "unprognostic (1.31e-2)" "unprognostic (3.45e-1)" "unprognostic (6.52e-2)" "unprognostic (3.60e-2)" "unprognostic (1.25e-1)" "unprognostic (2.95e-2)" "unprognostic (9.19e-2)" "unprognostic (1.51e-2)" "unprognostic (4.57e-2)" "unprognostic (1.47e-1)" "unprognostic (2.34e-2)" "unprognostic (4.91e-1)" "unprognostic (9.47e-2)" "unprognostic (1.78e-1)" "unprognostic (3.49e-1)" "unprognostic (2.27e-2)" "unprognostic (9.13e-2)" RIMS1 "CORD7, KIAA0340, RAB3IP2, RIM, RIM1" ENSG00000079841 "Regulating synaptic membrane exocytosis 1" Q86UR5 6 71886550-72403150 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Exocytosis, Neurotransmitter transport, Sensory transduction, Transport, Vision" "Cone-rod dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "brain: 59.7" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 1470.4;Brain inhibitory neurons: 680.9;Conjunctival goblet cells: 559.2;Corticotrophs: 767.8;Lactotrophs: 1100.6;Oligodendrocyte progenitor cells: 451.2;Other brain neurons: 665.5;Respiratory secretory cells: 438.5;Retinal amacrine cells: 397.6;Retinal bipolar cells: 528.8;Somatotrophs: 1212.3;Thyrotrophs: 1475.6" "Cell type enhanced" "Detected in all" "upper rhombic lip: 3566.2" "Cancer enhanced" "Detected in some" "Kidney Chromophobe (TCGA): 4.4" "Region enriched" "Detected in all" 7 "cerebellum: 849.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 2.6;prostate cancer: 3.7" "Adrenal gland - Adrenal medulla cells, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Lactotropes, Skin - Eccrine sweat gland cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 470.0" HPA076565 Enhanced NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 35: Non-specific - DNA binding" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 9 "HPA076565: " "unprognostic (1.63e-3)" "unprognostic (2.49e-1)" "unprognostic (3.58e-2)" "unprognostic (6.56e-3)" "unprognostic (1.41e-2)" "unprognostic (1.10e-2)" "unprognostic (2.01e-1)" "unprognostic (1.48e-1)" RIMS2 "KIAA0751, OBOE, RAB3IP3, RIM2" ENSG00000176406 "Regulating synaptic membrane exocytosis 2" Q9UQ26 8 103500610-104254430 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Differentiation "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "adrenal gland: 45.5;brain: 41.6;retina: 72.6" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 1451.5;Brain inhibitory neurons: 1833.5;Cone photoreceptor cells: 3568.9;Corticotrophs: 2249.2;Gonadotrophs: 2482.8;Lactotrophs: 3054.8;Other brain neurons: 1241.4;Pancreatic islet cells: 1181.8;Retinal bipolar cells: 2072.8;Retinal ganglion cells: 1456.3;Rod photoreceptor cells: 5187.5;Somatotrophs: 2578.3;Thyrotrophs: 3098.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 17.3" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Pituitary gland - Lactotropes, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046538, HPA066498, CAB079049" Enhanced Supported Approved "Plasma membrane,Cytosol" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 34: Non-specific - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 2 "Plasma membrane, Cytosol" "CAB079049: , HPA046538: , HPA066498: " "unprognostic (3.57e-2)" "unprognostic (3.35e-1)" "unprognostic (6.73e-2)" "unprognostic (2.40e-1)" "unprognostic (2.44e-1)" "unprognostic (2.31e-3)" "unprognostic (1.09e-2)" "unprognostic (9.30e-2)" "potential prognostic favorable (5.83e-7)" "unprognostic (1.77e-1)" "unprognostic (3.70e-1)" "unprognostic (2.91e-2)" "unprognostic (2.33e-1)" "unprognostic (8.69e-3)" "unprognostic (2.15e-2)" "unprognostic (2.56e-3)" "unprognostic (1.54e-1)" "unprognostic (6.09e-2)" "unprognostic (3.32e-2)" "unprognostic (1.36e-1)" "unprognostic (1.11e-1)" "unprognostic (2.03e-1)" RIMS3 "NIM3, RIM3" ENSG00000117016 "Regulating synaptic membrane exocytosis 3" Q9UJD0 1 40620680-40665682 "Predicted intracellular proteins" "Exocytosis, Neurotransmitter transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "brain: 97.9" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 42.5;Brain excitatory neurons: 25.4;Brain inhibitory neurons: 28.3;Early spermatids: 17.8;Late spermatids: 60.4;Müller glia: 12.4;Other brain neurons: 25.5;pDCs: 19.8;Smooth muscle cells: 14.8" "Cell type enhanced" "Detected in all" "midbrain-derived inhibitory: 96.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.5" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in all" "Neuroblastoma: 47.3" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal medulla cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055285 Approved Nucleoplasm,Nucleoli,Mitochondria NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 109: Neurons - Neuronal signaling" 5 "Nucleoli, Mitochondria" Nucleoplasm "HPA055285: " "unprognostic (2.14e-1)" "unprognostic (2.65e-1)" "unprognostic (1.10e-1)" "potential prognostic unfavorable (8.97e-4)" "unprognostic (2.91e-3)" "potential prognostic favorable (4.89e-4)" "unprognostic (4.54e-1)" "unprognostic (1.16e-3)" "unprognostic (2.81e-2)" "unprognostic (8.92e-2)" "unprognostic (9.99e-3)" "unprognostic (1.56e-2)" "unprognostic (1.90e-1)" "unprognostic (3.23e-2)" "unprognostic (1.12e-1)" "unprognostic (1.49e-1)" "unprognostic (5.91e-2)" "unprognostic (3.36e-2)" "unprognostic (2.66e-2)" "unprognostic (3.81e-3)" "unprognostic (1.05e-1)" "unprognostic (3.00e-1)" "unprognostic (4.88e-2)" "unprognostic (1.35e-2)" RIMS4 "C20orf190, dJ781B1.3" ENSG00000101098 "Regulating synaptic membrane exocytosis 4" Q9H426 20 44751808-44810546 "Predicted intracellular proteins" "Exocytosis, Neurotransmitter transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 40.4" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 21.3;Brain excitatory neurons: 15.5;Brain inhibitory neurons: 22.8;Corticotrophs: 21.4;Epididymal efferent duct absorptive cells: 22.9;Gonadotrophs: 37.8;Granulosa cells: 76.2;Pituicytes/FSCs: 14.4;Pituitary stem cells: 17.8;Retinal amacrine cells: 43.5;Retinal ganglion cells: 23.2;Retinal horizontal cells: 30.1;Sertoli cells: 22.1" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 11.0;Glioblastoma Multiforme (TCGA): 11.5;Ovary Serous Cystadenocarcinoma (TCGA): 12.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "Neuroblastoma: 25.3" "Adrenal gland - Adrenal medulla cells, Breast - Fibroblasts, Lung - Alveolar cells type 2, Pituitary gland - Corticotropes, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060928 Approved Approved Nucleoplasm NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 1 Nucleoplasm "HPA060928: " "unprognostic (2.25e-1)" "unprognostic (1.45e-2)" "unprognostic (2.14e-1)" "unprognostic (5.89e-2)" "unprognostic (5.16e-2)" "unprognostic (4.77e-3)" "unprognostic (9.34e-2)" "unprognostic (4.82e-2)" "unprognostic (1.93e-2)" "unprognostic (2.91e-1)" "unprognostic (1.01e-2)" "unprognostic (1.23e-2)" RIN1 ENSG00000174791 "Ras and Rab interactor 1" Q13671 11 66330241-66336840 "Predicted intracellular proteins, RAS pathway related proteins" Endocytosis "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 9.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 20.6;Brain excitatory neurons: 16.8;Esophageal basal cells: 54.6;Esophageal suprabasal cells: 16.9;Fallopian tube ciliated cells: 16.6;Thymic myoid cells: 23.1" "Cell type enhanced" "Detected in many" "hippocampal dentate gyrus: 45.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 9.8" "Lineage enriched" "Detected in many" 6 "monocytes: 9.8" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Liver - Vascular endothelial cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in many" HPA035491 Uncertain NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 2: Non-specific - Mixed function" "Cluster 29: Forebrain - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 35: Neurons - Synaptic function & neurogenesis" 63 "HPA035491: " "potential prognostic unfavorable (3.59e-4)" "unprognostic (2.77e-2)" "unprognostic (7.71e-2)" "unprognostic (2.22e-2)" "unprognostic (3.85e-1)" "unprognostic (8.74e-2)" "validated prognostic unfavorable (2.61e-4)" "validated prognostic unfavorable (8.78e-4)" "unprognostic (1.27e-1)" "unprognostic (1.83e-2)" "unprognostic (3.24e-2)" "unprognostic (2.67e-1)" "unprognostic (3.52e-1)" "unprognostic (3.36e-3)" "unprognostic (2.55e-3)" "unprognostic (1.05e-2)" "unprognostic (1.79e-2)" "unprognostic (1.51e-3)" "unprognostic (5.23e-2)" "unprognostic (6.02e-2)" "unprognostic (2.72e-1)" "unprognostic (2.94e-1)" "potential prognostic favorable (2.97e-5)" "unprognostic (3.49e-2)" "unprognostic (1.10e-2)" "unprognostic (4.05e-3)" "unprognostic (3.21e-2)" "unprognostic (3.75e-2)" "unprognostic (1.16e-1)" RIN2 RASSF4 ENSG00000132669 "Ras and Rab interactor 2" Q8WYP3 20 19757606-20002457 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Endocytosis "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.6" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034641 Approved Approved "Nucleoli,Golgi apparatus,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 13: Lung - Secretion" "Cluster 47: Endothelial cells - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 1 Cytosol "Nucleoli, Golgi apparatus" "HPA034641: " "unprognostic (3.41e-2)" "unprognostic (7.38e-2)" "unprognostic (5.60e-3)" "unprognostic (1.38e-2)" "unprognostic (1.23e-1)" "unprognostic (1.56e-1)" "unprognostic (1.98e-1)" "unprognostic (3.44e-3)" "unprognostic (5.88e-2)" "unprognostic (5.92e-2)" "validated prognostic favorable (3.13e-8)" "validated prognostic favorable (1.51e-4)" "unprognostic (8.20e-2)" "unprognostic (2.23e-1)" "unprognostic (1.12e-1)" "unprognostic (4.06e-2)" "unprognostic (2.05e-2)" "unprognostic (3.51e-3)" "unprognostic (5.33e-2)" "unprognostic (1.04e-2)" "unprognostic (2.73e-3)" "unprognostic (6.27e-2)" "unprognostic (4.63e-2)" "unprognostic (3.43e-1)" "unprognostic (3.59e-2)" "unprognostic (1.27e-1)" "unprognostic (3.68e-2)" "unprognostic (4.73e-1)" "unprognostic (1.72e-1)" "unprognostic (6.42e-3)" "unprognostic (1.64e-1)" RIN3 FLJ22439 ENSG00000100599 "Ras and Rab interactor 3" Q8TB24 14 92513781-92688994 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 43.7" "Cell type enhanced" "Detected in many" "cDC: 281.2;Hofbauer cells: 193.4;Innate lymphoid cells: 198.4;Kupffer cells: 347.4;Macrophages: 288.6;Mast cells: 244.5;Megakaryocyte progenitors: 213.7;Microglia: 423.5;monocytes: 537.5;Neutrophil progenitors: 504.8;Neutrophils: 626.6;NK-cells: 322.2" "Group enriched" "Detected in many" 9 "central nervous system macrophage: 588.4;leukocyte: 336.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 35.9;classical monocyte: 43.5;eosinophil: 54.2;intermediate monocyte: 40.4;myeloid DC: 41.6;neutrophil: 40.4;NK-cell: 21.5;non-classical monocyte: 51.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Minor Salivary Gland - Macrophages, Spleen - Neutrophils_2, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA079218 Approved NA NA 9700 "Cluster 25: Non-specific - Unknown function" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 16 "HPA079218: " "unprognostic (2.58e-2)" "unprognostic (2.20e-1)" "unprognostic (3.34e-2)" "unprognostic (1.87e-3)" "unprognostic (3.11e-1)" "unprognostic (2.62e-2)" "unprognostic (2.85e-2)" "unprognostic (3.08e-2)" "unprognostic (1.21e-1)" "unprognostic (1.91e-1)" "unprognostic (7.72e-3)" "unprognostic (1.79e-1)" "unprognostic (8.41e-2)" "unprognostic (7.39e-2)" "unprognostic (3.99e-2)" "unprognostic (9.61e-2)" "unprognostic (4.16e-2)" "unprognostic (4.56e-2)" "unprognostic (1.76e-1)" "unprognostic (8.81e-3)" "unprognostic (3.77e-2)" "unprognostic (9.18e-2)" "unprognostic (3.06e-2)" "unprognostic (5.35e-2)" "unprognostic (8.51e-2)" "unprognostic (5.89e-2)" "unprognostic (5.96e-2)" "unprognostic (1.23e-1)" "unprognostic (1.14e-1)" "unprognostic (8.31e-2)" "unprognostic (3.47e-2)" RING1 RNF1 ENSG00000204227 "Ring finger protein 1" Q06587 6 33208500-33212722 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Chromatin regulator, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 42.6;Bergmann glia: 50.1;Brain excitatory neurons: 30.7;Brain inhibitory neurons: 31.5;Ependymal cells: 41.8;Oligodendrocyte progenitor cells: 28.0;Oligodendrocytes: 28.6;Other brain neurons: 33.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008701 Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 28: Non-specific - Nuclear processes" "Cluster 98: Neurons - Neurotransmission & signaling" 129 Nucleoplasm Cytosol "HPA008701: " "unprognostic (4.35e-2)" "unprognostic (6.61e-3)" "unprognostic (1.37e-1)" "unprognostic (9.74e-3)" "unprognostic (1.80e-1)" "unprognostic (9.18e-2)" "unprognostic (4.99e-2)" "unprognostic (1.66e-2)" "unprognostic (1.62e-1)" "unprognostic (1.06e-1)" "unprognostic (9.61e-3)" "unprognostic (5.87e-3)" "unprognostic (1.79e-3)" "unprognostic (3.58e-1)" "unprognostic (1.71e-1)" "unprognostic (5.62e-2)" "unprognostic (1.78e-3)" "unprognostic (1.19e-1)" "unprognostic (3.54e-3)" "unprognostic (8.41e-2)" "unprognostic (2.06e-1)" "unprognostic (8.71e-3)" "potential prognostic unfavorable (9.67e-4)" "unprognostic (2.00e-3)" "unprognostic (4.90e-1)" "unprognostic (1.18e-1)" "unprognostic (3.87e-2)" "unprognostic (2.85e-2)" "unprognostic (2.59e-1)" "unprognostic (1.17e-1)" "unprognostic (3.15e-2)" RINL FLJ45909 ENSG00000187994 "Ras and Rab interactor like" Q6ZS11 19 38867830-38878275 "Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "NK-cells: 12.1;T-cells: 7.9" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 15.7;leukocyte: 16.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "lymphoma: 10.4" "Kidney - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA042083, HPA042103" Uncertain Approved Nucleoplasm,Vesicles No No "Cluster 14: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 37: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 1 "Nucleoplasm, Vesicles" "HPA042083: , HPA042103: " "unprognostic (4.06e-2)" "unprognostic (1.96e-1)" "unprognostic (2.18e-3)" "unprognostic (2.33e-2)" "unprognostic (6.56e-2)" "unprognostic (3.97e-2)" "unprognostic (5.16e-3)" "unprognostic (2.54e-3)" "potential prognostic favorable (9.70e-4)" "unprognostic (2.26e-2)" "potential prognostic favorable (1.17e-5)" "unprognostic (2.76e-1)" "unprognostic (1.08e-1)" "unprognostic (1.60e-2)" "potential prognostic unfavorable (1.16e-4)" "unprognostic (4.66e-3)" "unprognostic (9.81e-2)" "unprognostic (1.13e-1)" "unprognostic (1.54e-1)" "unprognostic (5.10e-3)" "unprognostic (4.08e-2)" "unprognostic (1.44e-1)" "unprognostic (6.15e-2)" "unprognostic (6.75e-2)" "unprognostic (2.67e-2)" "unprognostic (8.55e-2)" "unprognostic (1.33e-2)" "unprognostic (1.45e-1)" "unprognostic (2.41e-1)" "unprognostic (3.51e-2)" "unprognostic (3.38e-1)" RINT1 "FLJ11785, RINT-1" ENSG00000135249 "RAD50 interactor 1" Q6NUQ1 7 105532169-105567677 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Cell cycle, ER-Golgi transport, Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019875, HPA031646" Approved Approved "Golgi apparatus" Yes No "Cluster 3: Non-specific - Nuclear processes" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 39: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 111 "Golgi apparatus" "HPA019875: , HPA031646: " "unprognostic (4.71e-3)" "unprognostic (1.04e-2)" "unprognostic (7.16e-3)" "unprognostic (5.69e-2)" "unprognostic (9.89e-2)" "unprognostic (3.49e-1)" "unprognostic (1.16e-1)" "unprognostic (2.27e-2)" "unprognostic (2.01e-1)" "unprognostic (6.14e-2)" "potential prognostic favorable (1.43e-6)" "unprognostic (4.53e-1)" "unprognostic (1.06e-1)" "unprognostic (3.96e-2)" "unprognostic (6.03e-3)" "unprognostic (8.82e-2)" "unprognostic (3.18e-2)" "unprognostic (1.88e-1)" "unprognostic (8.12e-2)" "unprognostic (4.00e-2)" "unprognostic (3.06e-1)" "unprognostic (7.54e-2)" "potential prognostic unfavorable (5.81e-4)" "unprognostic (8.74e-2)" "unprognostic (3.37e-2)" "unprognostic (1.90e-1)" "unprognostic (9.12e-3)" "unprognostic (3.64e-2)" "unprognostic (8.61e-2)" "unprognostic (2.51e-2)" "unprognostic (1.62e-1)" RIOK1 "AD034, bA288G3.1, FLJ30006, RRP10" ENSG00000124784 "RIO kinase 1" Q9BRS2 6 7389793-7418037 "Enzymes, Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis" "Hydrolase, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 116.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017866, HPA051446" Enhanced Supported Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 39: Testis - Nuclear processes" "Cluster 25: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 92 Cytosol "HPA017866: , HPA051446: " "unprognostic (2.23e-2)" "unprognostic (3.24e-3)" "unprognostic (3.58e-1)" "unprognostic (1.79e-2)" "unprognostic (9.38e-2)" "unprognostic (4.42e-2)" "unprognostic (8.28e-2)" "unprognostic (6.48e-3)" "unprognostic (3.80e-2)" "unprognostic (7.23e-2)" "potential prognostic favorable (1.16e-5)" "unprognostic (3.30e-3)" "unprognostic (1.43e-2)" "potential prognostic unfavorable (5.37e-4)" "unprognostic (2.01e-3)" "unprognostic (2.71e-3)" "unprognostic (4.82e-2)" "unprognostic (4.62e-2)" "unprognostic (7.83e-3)" "unprognostic (2.63e-1)" "unprognostic (3.37e-1)" "unprognostic (3.29e-1)" "unprognostic (2.28e-2)" "unprognostic (1.47e-1)" "unprognostic (4.75e-2)" "unprognostic (9.97e-2)" "unprognostic (1.14e-2)" "unprognostic (4.31e-1)" "unprognostic (1.83e-1)" "unprognostic (5.43e-3)" "unprognostic (9.67e-2)" RIOK2 FLJ11159 ENSG00000058729 "RIO kinase 2" Q9BVS4 5 97160867-97183247 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Ribosome biogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005681 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 17: Non-specific - RNA processing" 29 Cytosol "Plasma membrane" "HPA005681: " "unprognostic (3.60e-2)" "unprognostic (3.11e-2)" "unprognostic (1.31e-1)" "unprognostic (6.58e-2)" "unprognostic (1.04e-1)" "unprognostic (4.00e-2)" "unprognostic (3.95e-2)" "unprognostic (1.72e-2)" "unprognostic (1.57e-2)" "unprognostic (1.63e-2)" "unprognostic (7.52e-2)" "unprognostic (1.05e-1)" "unprognostic (2.79e-2)" "unprognostic (1.08e-3)" "unprognostic (2.03e-1)" "potential prognostic unfavorable (7.20e-4)" "unprognostic (1.87e-2)" "unprognostic (7.86e-2)" "unprognostic (1.80e-1)" "unprognostic (1.77e-1)" "potential prognostic unfavorable (7.69e-4)" "unprognostic (5.97e-3)" "unprognostic (4.39e-3)" "unprognostic (3.51e-2)" "unprognostic (9.02e-2)" "unprognostic (6.04e-3)" "unprognostic (1.45e-1)" "unprognostic (1.25e-1)" "unprognostic (3.26e-1)" "unprognostic (1.39e-2)" "unprognostic (2.25e-1)" RIOK3 SUDD ENSG00000101782 "RIO kinase 3" O14730 18 23453287-23486603 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity, Ribosome biogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 164.5" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1542.4;Neutrophil progenitors: 787.9;Neutrophils: 608.7;Ocular epithelial cells: 637.5;Platelets: 1067.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001620, HPA024184" Approved Approved "Golgi apparatus,Plasma membrane,Centriolar satellite,Cytosol" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 46 "Plasma membrane, Cytosol" "Golgi apparatus, Centriolar satellite" "HPA001620: , HPA024184: " "unprognostic (2.68e-1)" "unprognostic (1.75e-1)" "unprognostic (1.69e-1)" "unprognostic (2.13e-2)" "unprognostic (1.29e-1)" "unprognostic (1.45e-2)" "unprognostic (1.88e-1)" "unprognostic (4.64e-2)" "unprognostic (8.99e-2)" "unprognostic (4.50e-2)" "validated prognostic favorable (1.14e-7)" "validated prognostic favorable (3.83e-4)" "unprognostic (1.13e-1)" "unprognostic (2.53e-3)" "unprognostic (8.39e-2)" "unprognostic (6.64e-2)" "unprognostic (2.20e-1)" "unprognostic (1.77e-1)" "unprognostic (2.48e-1)" "unprognostic (1.22e-1)" "unprognostic (2.85e-2)" "unprognostic (4.24e-3)" "unprognostic (1.67e-1)" "unprognostic (3.18e-2)" "unprognostic (1.73e-2)" "unprognostic (7.36e-3)" "unprognostic (1.57e-1)" "unprognostic (2.49e-1)" "unprognostic (1.62e-1)" "unprognostic (4.21e-2)" "unprognostic (1.37e-1)" RIOX1 "C14orf169, FLJ21802, JMJD9, MAPJD, NO66" ENSG00000170468 "Ribosomal oxygenase 1" Q9H6W3 14 73490933-73493394 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Dioxygenase, Oxidoreductase, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 27.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003730 Supported "Nucleoli rim" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 1 "Nucleoli rim" "HPA003730: " "unprognostic (1.56e-1)" "unprognostic (9.62e-2)" "unprognostic (1.68e-1)" "unprognostic (4.09e-3)" "unprognostic (4.52e-2)" "unprognostic (5.53e-3)" "unprognostic (2.85e-1)" "unprognostic (2.24e-1)" "unprognostic (3.15e-2)" "unprognostic (1.11e-1)" "unprognostic (8.51e-3)" "unprognostic (2.44e-2)" "unprognostic (4.96e-2)" "unprognostic (1.67e-1)" "unprognostic (5.80e-2)" "unprognostic (1.16e-2)" "unprognostic (2.61e-1)" "unprognostic (6.94e-3)" "unprognostic (1.01e-3)" "unprognostic (6.76e-2)" "unprognostic (9.71e-2)" "unprognostic (1.26e-1)" "unprognostic (9.41e-2)" "unprognostic (5.64e-2)" "unprognostic (1.84e-1)" "unprognostic (1.55e-1)" "unprognostic (3.32e-2)" "unprognostic (7.80e-2)" RIOX2 "FLJ14393, JMJD10, mdig, MINA, MINA53, NO52" ENSG00000170854 "Ribosomal oxygenase 2" Q8IUF8 3 97941818-97972457 "Predicted intracellular proteins" "Ribosome biogenesis, Transcription, Transcription regulation" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007603, HPA008080, CAB013458" Supported Supported Nucleoplasm,Nucleoli NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 33: Thyroid gland - Tissue development" "Cluster 39: Astrocytes - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 8 "Nucleoplasm, Nucleoli" "CAB013458: , HPA007603: , HPA008080: " "unprognostic (2.04e-1)" "potential prognostic unfavorable (4.45e-5)" "unprognostic (5.65e-3)" "unprognostic (4.31e-1)" "unprognostic (2.08e-2)" "unprognostic (3.12e-1)" "unprognostic (8.77e-2)" "unprognostic (1.50e-1)" "unprognostic (5.32e-2)" "unprognostic (1.69e-1)" "potential prognostic unfavorable (2.44e-4)" "unprognostic (3.06e-2)" "unprognostic (2.71e-3)" "unprognostic (2.45e-1)" "unprognostic (2.10e-3)" "unprognostic (2.56e-1)" "unprognostic (1.28e-1)" "unprognostic (5.87e-2)" "unprognostic (6.72e-3)" "unprognostic (3.96e-2)" "unprognostic (4.84e-1)" "unprognostic (2.77e-2)" "potential prognostic favorable (5.46e-4)" "unprognostic (5.36e-2)" "unprognostic (2.85e-1)" "unprognostic (7.00e-2)" "unprognostic (1.17e-1)" "potential prognostic unfavorable (3.40e-4)" "unprognostic (2.83e-1)" RIPK1 "RIP, RIP-1, RIP1" ENSG00000137275 "Receptor interacting serine/threonine kinase 1" Q13546 6 3063824-3115187 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Inflammatory response, Necrosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Colonocytes: 309.7;Enterocytes: 345.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010302, HPA015257" Supported Approved "Plasma membrane,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 28: Non-specific - Nuclear processes" "Cluster 65: Non-specific - Cell growth & division" 97 "Plasma membrane, Cytosol" "CAB010302: , HPA015257: " "unprognostic (1.05e-1)" "unprognostic (9.89e-2)" "unprognostic (2.45e-1)" "unprognostic (1.24e-1)" "unprognostic (9.48e-3)" "unprognostic (5.18e-2)" "unprognostic (4.73e-1)" "unprognostic (4.98e-3)" "unprognostic (1.50e-2)" "unprognostic (3.97e-1)" "validated prognostic favorable (2.95e-9)" "validated prognostic favorable (8.86e-4)" "unprognostic (1.11e-1)" "unprognostic (2.27e-1)" "unprognostic (2.51e-2)" "unprognostic (2.80e-1)" "unprognostic (1.54e-1)" "unprognostic (6.68e-3)" "unprognostic (1.61e-1)" "unprognostic (2.71e-1)" "unprognostic (2.32e-1)" "unprognostic (1.66e-1)" "unprognostic (1.14e-1)" "unprognostic (3.51e-1)" "unprognostic (1.75e-1)" "unprognostic (1.04e-1)" "unprognostic (1.40e-1)" "unprognostic (1.50e-1)" "unprognostic (1.34e-1)" "unprognostic (7.84e-3)" "unprognostic (4.74e-2)" RIPK2 "CARD3, CARDIAK, RICK, RIP2" ENSG00000104312 "Receptor interacting serine/threonine kinase 2" O43353 8 89757806-89791064 "Enzymes, Predicted intracellular proteins" "Adaptive immunity, Apoptosis, Immunity, Innate immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "cDC: 241.9;Endometrial glandular cells: 399.3;Endometrial luminal cells: 236.2;Megakaryocyte-Erythroid progenitors: 241.7;Monocyte progenitors: 252.1;monocytes: 382.3;Pancreatic duct cells: 302.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015273, HPA016499" Approved Enhanced Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 39: Astrocytes - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 51: Secretory epithelial cells - Mixed function" 42 Cytosol "HPA015273: , HPA016499: " "unprognostic (8.07e-2)" "unprognostic (9.20e-2)" "unprognostic (2.21e-1)" "potential prognostic unfavorable (9.06e-4)" "unprognostic (8.95e-2)" "unprognostic (6.98e-2)" "unprognostic (3.23e-2)" "potential prognostic favorable (2.05e-4)" "unprognostic (1.99e-1)" "unprognostic (3.07e-3)" "unprognostic (9.98e-3)" "potential prognostic unfavorable (5.76e-4)" "potential prognostic unfavorable (2.21e-6)" "unprognostic (4.53e-3)" "unprognostic (5.50e-3)" "potential prognostic unfavorable (2.55e-4)" "unprognostic (1.05e-1)" "unprognostic (1.25e-1)" "unprognostic (1.96e-1)" "unprognostic (4.08e-1)" "unprognostic (2.89e-1)" "potential prognostic unfavorable (3.93e-4)" "unprognostic (1.86e-3)" "unprognostic (1.94e-2)" "unprognostic (1.04e-2)" "unprognostic (3.79e-3)" "unprognostic (2.09e-2)" "unprognostic (5.90e-2)" "unprognostic (4.47e-1)" "unprognostic (7.27e-2)" "unprognostic (7.65e-2)" RIPK3 RIP3 ENSG00000129465 "Receptor interacting serine/threonine kinase 3" Q9Y572 14 24336025-24340022 "Enzymes, Predicted intracellular proteins, Transporters" "Apoptosis, Host-virus interaction, Necrosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Colonocytes: 2.8;Enterocytes: 2.7;Foveolar cells: 3.2;Goblet cells: 2.4;Hofbauer cells: 2.1;Kupffer cells: 3.1;Microglia: 4.2;Neuroendocrine cells: 2.6;Neutrophils: 1.7;pDCs: 2.6;Respiratory ionocytes: 2.5" "Group enriched" "Detected in some" 4 "central nervous system macrophage: 5.6;endothelial cell: 3.7;leukocyte: 6.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "colorectal cancer: 3.2" "Adrenal gland - Macrophages, Skeletal muscle - Endothelial cells, Testis - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 5: Spleen - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 15: Non-specific - Protein processing" 24 "unprognostic (4.89e-2)" "unprognostic (8.00e-2)" "unprognostic (3.61e-2)" "unprognostic (7.51e-2)" "potential prognostic favorable (3.60e-4)" "unprognostic (1.14e-1)" "unprognostic (3.73e-2)" "unprognostic (1.45e-1)" "unprognostic (7.80e-2)" "unprognostic (2.19e-1)" "unprognostic (1.11e-1)" "unprognostic (1.67e-1)" "unprognostic (2.48e-3)" "unprognostic (1.22e-2)" "unprognostic (1.70e-1)" "unprognostic (2.62e-3)" "unprognostic (1.37e-1)" "unprognostic (9.16e-2)" "unprognostic (1.50e-1)" "unprognostic (2.61e-2)" "unprognostic (3.30e-1)" "unprognostic (2.75e-2)" "unprognostic (1.53e-2)" "unprognostic (2.75e-1)" "unprognostic (2.18e-1)" "unprognostic (2.49e-2)" "unprognostic (7.13e-2)" "unprognostic (1.12e-1)" RIPK4 "ANKK2, ANKRD3, DIK, PKK, RIP4" ENSG00000183421 "Receptor interacting serine/threonine kinase 4" P57078 21 41739369-41767089 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 69.6" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 89.3;Endometrial glandular cells: 277.4;Endometrial luminal cells: 282.3;Endometrial secretory cells: 123.5;Esophageal apical cells: 267.2;Esophageal suprabasal cells: 116.7;Prostatic hillock cells: 84.8" "Group enriched" "Detected in some" 7 "choroid plexus epithelial cell: 2.4;ependymal cell: 4.3;vascular associated smooth muscle cell: 1.7" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 6 "choroid plexus: 7.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Pituitary gland - Corticotropes, Stomach - Gastric mucous cells, Testis - Spermatogonia" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA030942, HPA079641" Enhanced Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 3: Choroid plexus - Cilium" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 47 "Vesicles, Cytosol" "Plasma membrane" "HPA030942: , HPA079641: " "unprognostic (3.11e-2)" "unprognostic (8.20e-2)" "unprognostic (1.83e-1)" "unprognostic (2.11e-1)" "unprognostic (2.24e-1)" "unprognostic (2.66e-3)" "unprognostic (5.63e-2)" "unprognostic (6.56e-2)" "potential prognostic favorable (4.26e-6)" "unprognostic (5.96e-3)" "unprognostic (1.60e-3)" "unprognostic (5.41e-2)" "unprognostic (2.67e-2)" "unprognostic (6.14e-2)" "unprognostic (1.90e-2)" "unprognostic (3.02e-1)" "unprognostic (2.09e-1)" "potential prognostic unfavorable (3.12e-5)" "unprognostic (1.12e-1)" "potential prognostic unfavorable (4.07e-4)" "unprognostic (2.22e-1)" "unprognostic (1.50e-1)" "unprognostic (7.57e-2)" "unprognostic (7.05e-2)" "unprognostic (2.14e-1)" "unprognostic (3.04e-1)" "unprognostic (7.60e-3)" "unprognostic (1.41e-1)" "unprognostic (5.34e-2)" RIPOR1 "FAM65A, FLJ13725" ENSG00000039523 "RHO family interacting cell polarization regulator 1" Q6ZS17 16 67518418-67546788 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "Podocytes: 771.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 11.2;eosinophil: 9.4;intermediate monocyte: 15.6;memory B-cell: 15.9;myeloid DC: 10.2;naive B-cell: 9.5;neutrophil: 6.6;non-classical monocyte: 15.2;plasmacytoid DC: 14.4" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Lung - Endothelial cells, Skeletal muscle - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005923 Uncertain Supported "Golgi apparatus,Cytosol" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 57: Podocytes - Glomerular filtration" "Golgi apparatus" Cytosol "HPA005923: " "unprognostic (2.09e-1)" "unprognostic (1.74e-1)" "unprognostic (3.20e-3)" "unprognostic (1.01e-2)" "unprognostic (1.43e-2)" "unprognostic (1.25e-1)" "unprognostic (1.24e-1)" "unprognostic (2.39e-3)" "unprognostic (1.27e-2)" "potential prognostic favorable (1.12e-7)" "unprognostic (4.98e-2)" "unprognostic (8.83e-3)" "unprognostic (7.14e-3)" "unprognostic (3.07e-2)" "unprognostic (6.94e-2)" "potential prognostic unfavorable (5.18e-5)" "unprognostic (1.40e-1)" "unprognostic (6.35e-2)" "unprognostic (2.16e-1)" "unprognostic (1.58e-1)" "potential prognostic unfavorable (4.12e-4)" "unprognostic (3.24e-1)" "unprognostic (2.42e-1)" "unprognostic (3.68e-2)" "unprognostic (7.22e-2)" "unprognostic (6.94e-2)" "unprognostic (1.77e-1)" "unprognostic (1.57e-2)" "unprognostic (3.26e-1)" RIPOR2 "C6orf32, DIFF48, FAM65B, KIAA0386, MYONAP" ENSG00000111913 "RHO family interacting cell polarization regulator 2" Q9Y4F9 6 24804282-25042170 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell adhesion, Chemotaxis, Differentiation, Hearing, Myogenesis" "Developmental protein, Signal transduction inhibitor" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 49.3;lymphoid tissue: 77.3" "Group enriched" "Detected in many" 4 "Neutrophils: 7916.5;Platelets: 2770.6" "Cell type enhanced" "Detected in all" "leukocyte: 881.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 955.9" "Lineage enriched" "Detected in all" 5 "granulocytes: 955.9" "Cancer enhanced" "Detected in many" "lymphoma: 48.6" "Adipose visceral - Neutrophils, Liver - Neutrophils, Lung - Neutrophils_2, Spleen - Neutrophils_2, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA079394 Supported Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 33: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 5 Cytosol "HPA079394: " "unprognostic (2.14e-2)" "unprognostic (2.63e-2)" "unprognostic (4.52e-2)" "unprognostic (1.03e-1)" "unprognostic (1.68e-1)" "unprognostic (1.47e-2)" "unprognostic (1.51e-2)" "unprognostic (1.16e-2)" "unprognostic (3.09e-2)" "potential prognostic favorable (3.94e-5)" "unprognostic (1.06e-3)" "unprognostic (7.84e-2)" "unprognostic (1.08e-2)" "unprognostic (2.14e-3)" "unprognostic (8.91e-3)" "unprognostic (7.92e-2)" "unprognostic (2.82e-1)" "unprognostic (1.37e-2)" "unprognostic (8.99e-2)" "unprognostic (8.63e-2)" "unprognostic (6.45e-3)" "unprognostic (2.50e-2)" "unprognostic (1.29e-1)" "unprognostic (3.13e-2)" "unprognostic (7.06e-2)" "unprognostic (1.81e-1)" "unprognostic (7.46e-2)" "unprognostic (1.18e-1)" "unprognostic (4.41e-3)" RIPOR3 "C20orf175, C20orf176, dJ530I15.2, dJ530I15.3, FAM65C" ENSG00000042062 "RIPOR family member 3" Q96MK2 20 50586108-50691542 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 40.3" "Cell type enhanced" "Detected in many" "Epicardial cells: 252.4;Erythrocyte progenitors: 106.9;Fibro-adipogenic progenitors: 141.9;Fibroblasts: 108.0;Loop of henle epithelial cells: 212.7;Megakaryocyte-Erythroid progenitors: 128.4;Pericytes: 142.7;Platelets: 223.6;Proximal tubule cells: 76.0;Sertoli cells: 97.3" "Cell type enhanced" "Detected in all" "pericyte: 360.0;vascular associated smooth muscle cell: 102.4" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 6.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 8.3" "Colon - Endothelial cells, Kidney - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA051823, HPA054759" Uncertain Approved Nucleoplasm NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 6 Nucleoplasm "HPA051823: , HPA054759: " "unprognostic (5.46e-2)" "unprognostic (4.38e-2)" "unprognostic (1.11e-2)" "unprognostic (8.01e-2)" "unprognostic (1.83e-2)" "unprognostic (1.31e-2)" "potential prognostic favorable (1.73e-5)" "unprognostic (3.20e-2)" "validated prognostic favorable (1.37e-4)" "validated prognostic favorable (2.81e-4)" "unprognostic (2.78e-3)" "unprognostic (2.27e-1)" "unprognostic (7.20e-2)" "unprognostic (2.18e-2)" "unprognostic (2.41e-3)" "unprognostic (6.82e-3)" "unprognostic (1.15e-2)" "unprognostic (2.93e-1)" RIPPLY1 ENSG00000147223 "Ripply transcriptional repressor 1" Q0D2K3 X 106900063-106903341 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Developmental protein, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 2.8;liver: 5.4" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "Kidney Renal Papillary Cell Carcinoma (TCGA): 26.6" "Region enhanced" "Detected in single" "choroid plexus: 1.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Minor Salivary Gland - Minor salivary glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA052284 Uncertain NA NA "Cluster 16: Liver & Kidney - Metabolism" "Cluster 36: Choroid plexus - Mixed function" "Cluster 1: Neuronal - Visual perception" 36 "HPA052284: " "unprognostic (4.00e-3)" "unprognostic (1.59e-3)" "unprognostic (4.50e-3)" "unprognostic (2.54e-1)" RIPPLY2 "C6orf159, dJ237I15.1" ENSG00000203877 "Ripply transcriptional repressor 2" Q5TAB7 6 83853360-83857515 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein" Dwarfism "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 32.4;pituitary gland: 10.6" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 17.0;Brain inhibitory neurons: 15.4;Corticotrophs: 9.0;Gonadotrophs: 8.4;Lactotrophs: 8.9;Neuroendocrine cells: 7.1;Oligodendrocyte progenitor cells: 10.2;Oligodendrocytes: 6.6;Other brain neurons: 13.5;Pancreatic islet cells: 19.2;Retinal amacrine cells: 6.2;Retinal bipolar cells: 7.0;Retinal ganglion cells: 15.5;Retinal horizontal cells: 10.0" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in some" 5 "Bladder Urothelial Carcinoma (TCGA): 8.8;Glioblastoma Multiforme (TCGA): 6.7;Lung Squamous Cell Carcinoma (TCGA): 2.5;Pancreatic Adenocarcinoma (TCGA): 2.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 19.1" "Adrenal gland - Adrenal medulla cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047454 Uncertain NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 37: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 13 "HPA047454: " "unprognostic (8.35e-2)" "unprognostic (5.75e-2)" "potential prognostic favorable (6.51e-5)" "unprognostic (1.26e-2)" "unprognostic (6.39e-3)" RIPPLY3 DSCR6 ENSG00000183145 "Ripply transcriptional repressor 3" P57055 21 37006150-37019662 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Developmental protein, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 6.2;Alveolar cells type 2: 3.0;Epididymal principal cells: 5.1;Extravillous trophoblasts: 3.3;Migrating cytotrophoblasts: 2.5;Neuroendocrine cells: 2.3;Pancreatic islet cells: 3.9;Renal collecting duct principal cells: 2.3;Respiratory ionocytes: 2.5;Retinal pigment epithelial cells: 4.3;Transitional alveolar cells: 3.3" "Cell type enriched" "Detected in single" 8 "medium spiny neuron: 4.8" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in single" "basal ganglia: 1.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" HPA055541 Uncertain NA NA "Cluster 33: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 15 "HPA055541: " "unprognostic (2.13e-1)" "unprognostic (9.70e-2)" "unprognostic (7.79e-3)" "unprognostic (8.98e-2)" "unprognostic (2.15e-3)" "unprognostic (3.15e-1)" RIT1 "MGC125864, MGC125865, RIBB, RIT, ROC1" ENSG00000143622 "Ras like without CAAX 1" Q92963 1 155897808-155911404 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Hydrolase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 417.4;Neutrophils: 344.0;Platelets: 304.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053249 Approved NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 7 "HPA053249: " "unprognostic (1.50e-1)" "unprognostic (2.25e-2)" "unprognostic (2.57e-1)" "unprognostic (3.72e-3)" "unprognostic (1.31e-1)" "unprognostic (2.95e-1)" "unprognostic (8.52e-2)" "unprognostic (4.34e-2)" "unprognostic (3.89e-2)" "unprognostic (3.50e-3)" "validated prognostic favorable (1.33e-10)" "validated prognostic favorable (4.45e-4)" "unprognostic (4.28e-2)" "potential prognostic unfavorable (3.75e-7)" "unprognostic (1.24e-1)" "unprognostic (7.53e-2)" "unprognostic (1.11e-2)" "unprognostic (2.15e-1)" "unprognostic (2.70e-1)" "unprognostic (5.16e-2)" "unprognostic (2.13e-3)" "unprognostic (7.47e-3)" "unprognostic (1.83e-1)" "unprognostic (2.69e-2)" "unprognostic (6.59e-3)" "unprognostic (2.07e-1)" "unprognostic (4.80e-2)" "unprognostic (4.68e-2)" "unprognostic (2.24e-1)" "unprognostic (1.91e-1)" "unprognostic (2.47e-1)" RIT2 "RIBA, RIN" ENSG00000152214 "Ras like without CAAX 2" Q99578 18 42743227-43115691 "Enzymes, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 33 "brain: 61.5" "Group enriched" "Detected in some" 4 "Brain excitatory neurons: 523.1;Brain inhibitory neurons: 191.2;Oligodendrocyte progenitor cells: 303.3;Other brain neurons: 191.4;Retinal ganglion cells: 231.8" "Cell type enhanced" "Detected in all" "mammillary body: 772.1;upper rhombic lip: 1321.7" "Cancer enriched" "Detected in single" 51 "Glioblastoma Multiforme (TCGA): 11.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in all" "HPA072174, HPA072526" Enhanced Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 2: Neurons - Nucleosome" "Cluster 66: Non-specific - Mitochondria" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 3 Nucleoplasm "Golgi apparatus, Cytosol" "HPA072174: , HPA072526: " "unprognostic (4.38e-2)" "unprognostic (1.71e-1)" RITA1 "C12orf52, FLJ14827, RITA" ENSG00000139405 "RBPJ interacting and tubulin associated 1" Q96K30 12 113185526-113192368 "Predicted intracellular proteins" "Neurogenesis, Notch signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 57.8;Late spermatids: 45.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039094, HPA039095, HPA061531" Supported Supported "Nucleoplasm,Golgi apparatus,Primary cilium,Primary cilium tip,Cytosol" No No "Cluster 41: Basophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 93: Hepatocytes - Bile production & excretion" 6 Nucleoplasm "Golgi apparatus, Primary cilium, Primary cilium tip, Cytosol" "HPA039094: , HPA039095: , HPA061531: " "unprognostic (1.41e-1)" "unprognostic (1.87e-1)" "unprognostic (1.66e-1)" "unprognostic (1.42e-1)" "unprognostic (2.48e-2)" "unprognostic (4.58e-2)" "unprognostic (3.11e-2)" "unprognostic (3.26e-1)" "unprognostic (5.11e-2)" "potential prognostic favorable (7.67e-4)" "unprognostic (4.65e-2)" "unprognostic (1.99e-1)" "potential prognostic unfavorable (3.14e-4)" "unprognostic (1.96e-1)" "unprognostic (1.46e-2)" "unprognostic (2.17e-1)" "unprognostic (5.56e-2)" "unprognostic (1.47e-1)" "unprognostic (2.24e-2)" "unprognostic (5.06e-3)" "unprognostic (6.76e-2)" "unprognostic (5.50e-2)" "unprognostic (1.98e-1)" "unprognostic (2.28e-1)" "unprognostic (4.28e-1)" "unprognostic (8.61e-3)" "unprognostic (3.43e-1)" "unprognostic (2.45e-1)" "unprognostic (4.42e-3)" RLBP1 CRALBP ENSG00000140522 "Retinaldehyde binding protein 1" P12271 15 89209869-89221614 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Sensory transduction, Transport, Vision" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "retina: 246.4" "Group enriched" "Detected in some" 90 "Müller glia: 2970.2;Retinal pigment epithelial cells: 2510.9" "Group enriched" "Detected in some" 9 "astrocyte: 17.1;Bergmann glia: 8.3;choroid plexus epithelial cell: 8.6;oligodendrocyte precursor cell: 6.9" "Group enriched" "Detected in some" 28 "Glioblastoma Multiforme (TCGA): 7.0;Skin Cutaneous Melanoma (TCGA): 15.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "Bile duct cancer: 10.4;colorectal cancer: 3.5;skin cancer: 9.4" "Colon - Enteric glia cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042051, HPA044083" Enhanced Approved Supported Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 42: Retina - Visual perception" "Cluster 23: Choroid plexus - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 11: Muller glia cells - Retinal homeostasis" 1 Cytosol "Nucleoplasm, Centrosome" "HPA042051: , HPA044083: " "unprognostic (9.81e-2)" "unprognostic (1.39e-2)" "unprognostic (3.31e-2)" RLF "Zn-15L, ZNF292L" ENSG00000117000 "RLF zinc finger" Q13129 1 40161387-40240921 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 708.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054653, HPA057300" Uncertain Approved Nucleoplasm,Nucleoli Yes No "Cluster 35: Neutrophils - Protein binding" "Cluster 40: Non-specific - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 8 Nucleoplasm Nucleoli "HPA054653: , HPA057300: " "unprognostic (7.29e-2)" "unprognostic (3.75e-1)" "unprognostic (6.03e-2)" "unprognostic (3.70e-3)" "unprognostic (1.72e-1)" "unprognostic (1.97e-1)" "unprognostic (2.05e-1)" "unprognostic (9.26e-3)" "unprognostic (2.12e-1)" "potential prognostic unfavorable (4.53e-5)" "validated prognostic favorable (1.49e-5)" "validated prognostic favorable (6.19e-5)" "unprognostic (2.38e-2)" "potential prognostic unfavorable (8.88e-5)" "unprognostic (9.22e-2)" "unprognostic (3.18e-2)" "unprognostic (1.71e-3)" "unprognostic (2.81e-1)" "unprognostic (8.23e-2)" "unprognostic (1.40e-2)" "unprognostic (7.10e-3)" "unprognostic (4.94e-3)" "unprognostic (8.08e-2)" "unprognostic (5.31e-2)" "unprognostic (1.07e-2)" "unprognostic (1.11e-1)" "unprognostic (5.63e-2)" "unprognostic (3.28e-1)" "unprognostic (3.62e-1)" "unprognostic (3.76e-2)" "unprognostic (3.35e-1)" RLIM "MGC15161, NY-REN-43, RNF12" ENSG00000131263 "Ring finger protein, LIM domain interacting" Q9NVW2 X 74582976-74614624 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" Transferase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 38.9" "Cell type enhanced" "Detected in many" "Neutrophils: 191.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018895 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 14: Neurons - Synaptic function" "Cluster 36: Non-specific - mRNA processing" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 45 Nucleoplasm Cytosol "HPA018895: " "unprognostic (4.01e-2)" "unprognostic (7.86e-3)" "unprognostic (1.79e-1)" "unprognostic (1.22e-1)" "unprognostic (4.45e-1)" "unprognostic (2.52e-1)" "unprognostic (5.97e-2)" "unprognostic (4.98e-2)" "unprognostic (1.00e-1)" "unprognostic (2.65e-3)" "validated prognostic favorable (5.50e-4)" "validated prognostic favorable (5.58e-4)" "unprognostic (2.81e-2)" "unprognostic (6.95e-3)" "unprognostic (3.33e-1)" "unprognostic (2.16e-1)" "unprognostic (2.36e-3)" "unprognostic (8.53e-2)" "unprognostic (1.94e-1)" "unprognostic (8.00e-2)" "unprognostic (2.25e-2)" "unprognostic (5.59e-2)" "unprognostic (3.50e-2)" "unprognostic (8.01e-2)" "unprognostic (1.25e-2)" "unprognostic (3.67e-2)" "unprognostic (1.44e-1)" "unprognostic (1.41e-1)" "unprognostic (1.44e-1)" "unprognostic (4.59e-3)" "unprognostic (2.46e-1)" RLN1 H1 ENSG00000107018 "Relaxin 1" P04808 9 5334930-5339876 "Plasma proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 72 "prostate: 22.0" "Cell type enhanced" "Detected in some" "Early primary spermatocytes: 2.5;Epididymal efferent duct ciliated cells: 2.5;Fallopian tube ciliated cells: 7.0;Innate lymphoid cells: 2.5;Platelets: 2.8;Prostatic glandular cells: 19.2;Respiratory ionocytes: 2.5;Undifferentiated spermatogonia: 3.6" "Cell type enhanced" "Detected in some" "endothelial cell: 1.1;leukocyte: 1.6" "Cancer enriched" "Detected in single" 275 "Prostate Adenocarcinoma (TCGA): 112.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 59 "prostate cancer: 6.5" "Pituitary gland - Lactotropes, Prostate - Prostate glandular cells, Testis - Early spermatids" "Secreted to blood" Hormone NA NA "Cluster 38: Non-specific - Basic cellular processes" "Cluster 60: Prostate cancer - Unknown function" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 17 "unprognostic (3.18e-2)" "unprognostic (1.70e-3)" "unprognostic (1.62e-2)" RLN2 "bA12D24.1.1, bA12D24.1.2, H2, RLXH2" ENSG00000107014 "Relaxin 2" P04090 9 5299864-5304716 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 4.8" "Cell type enhanced" "Detected in many" "Epididymal efferent duct ciliated cells: 16.8;Fallopian tube ciliated cells: 9.3;Late primary spermatocytes: 29.5;Megakaryocytes: 12.4;Oocytes: 59.9;Syncytiotrophoblasts: 15.6" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 1.6;endothelial cell: 1.9;ependymal cell: 1.6" "Group enriched" "Detected in many" 5 "Breast Invasive Carcinoma (TCGA): 8.2;Prostate Adenocarcinoma (TCGA): 19.9" "Not detected" "Not detected" "Group enriched" "Detected in many" 26 "gdT-cell: 1.4;MAIT T-cell: 4.2;memory B-cell: 1.9;memory CD4 T-cell: 2.8;memory CD8 T-cell: 2.3;naive B-cell: 1.4;naive CD4 T-cell: 4.0;naive CD8 T-cell: 3.0;NK-cell: 3.5;T-reg: 1.4" "Group enriched" "Detected in many" 33 "B-cells: 1.9;NK-cells: 3.5;T-cells: 4.2" "Cancer enhanced" "Detected in many" "prostate cancer: 6.3" "Breast - Breast glandular cells, Prostate - Prostate glandular cells, Testis - Early spermatids" "Secreted to blood" Hormone NA NA 24400 "Cluster 24: Non-specific - Transcription" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 27: Breast cancer - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 2 "unprognostic (6.18e-2)" "unprognostic (1.80e-2)" "unprognostic (2.87e-1)" "unprognostic (1.59e-1)" "validated prognostic favorable (7.85e-6)" "validated prognostic favorable (1.26e-5)" "potential prognostic favorable (1.22e-6)" "unprognostic (2.28e-1)" "unprognostic (1.70e-1)" "unprognostic (3.32e-2)" "unprognostic (6.70e-2)" "unprognostic (8.21e-3)" "unprognostic (7.20e-2)" "unprognostic (1.16e-1)" "unprognostic (7.75e-3)" "unprognostic (1.33e-1)" "unprognostic (1.59e-1)" "unprognostic (7.83e-3)" "unprognostic (5.70e-2)" RLN3 "H3, RXN3, ZINS4" ENSG00000171136 "Relaxin 3" Q8WXF3 19 14028148-14031551 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "parathyroid gland: 1.5;testis: 2.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "midbrain: 11.7;pons and medulla: 27.2" "Region enriched" "Detected in many" 9 "pons: 31.2" "Secreted to blood" Hormone NA NA 60000000 "Cluster 79: Testis - Spermatogenesis" "Cluster 47: Leukemia - Hemostasis" "Cluster 98: Neurons - Neurotransmission & signaling" 1 RMC1 "C18orf8, HsT2591, MIC1, WDR98" ENSG00000141452 "Regulator of MON1-CCZ1" Q96DM3 18 23503470-23531822 "Cancer-related genes, Predicted intracellular proteins" Autophagy "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epididymal basal cells: 180.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043589 Uncertain Uncertain Nucleoplasm NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 31: Non-specific - Transcription" "Cluster 13: Non-specific - Mixed function" "Cluster 51: Secretory epithelial cells - Mixed function" 7 Nucleoplasm "HPA043589: " "unprognostic (9.36e-2)" "unprognostic (3.19e-2)" "unprognostic (9.77e-2)" "unprognostic (7.09e-3)" "unprognostic (8.92e-2)" "unprognostic (4.35e-2)" "unprognostic (8.84e-3)" "unprognostic (7.93e-2)" "unprognostic (1.79e-2)" "potential prognostic favorable (1.35e-6)" "unprognostic (1.69e-2)" "unprognostic (4.12e-2)" "unprognostic (2.02e-3)" "unprognostic (1.51e-1)" "unprognostic (4.52e-3)" "unprognostic (1.33e-1)" "unprognostic (1.74e-2)" "unprognostic (1.30e-1)" "unprognostic (6.47e-2)" "unprognostic (1.33e-1)" "unprognostic (1.31e-1)" "unprognostic (3.67e-2)" "unprognostic (3.00e-2)" "unprognostic (1.23e-1)" "unprognostic (2.54e-1)" "unprognostic (1.65e-1)" "unprognostic (1.09e-1)" "unprognostic (1.13e-1)" "unprognostic (1.87e-1)" RMDN1 "CGI-90, FAM82B, FLJ20665, RMD1" ENSG00000176623 "Regulator of microtubule dynamics 1" Q96DB5 8 86468257-86514357 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026495 Approved Supported "Actin filaments,Centrosome" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 25: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 10 Centrosome "Actin filaments" "HPA026495: " "unprognostic (1.91e-1)" "potential prognostic unfavorable (8.98e-4)" "unprognostic (2.09e-1)" "unprognostic (1.39e-1)" "unprognostic (2.48e-1)" "unprognostic (2.54e-2)" "unprognostic (2.04e-1)" "unprognostic (1.67e-2)" "potential prognostic unfavorable (2.14e-4)" "potential prognostic favorable (1.31e-4)" "unprognostic (5.09e-2)" "unprognostic (3.59e-2)" "unprognostic (3.44e-1)" "potential prognostic unfavorable (7.53e-4)" "unprognostic (4.65e-1)" "unprognostic (1.64e-1)" "unprognostic (2.96e-1)" "unprognostic (1.11e-1)" "unprognostic (2.42e-3)" "unprognostic (6.45e-2)" "unprognostic (1.25e-1)" "unprognostic (1.43e-1)" "unprognostic (2.31e-1)" "unprognostic (2.14e-1)" "unprognostic (1.19e-1)" "unprognostic (4.51e-2)" "unprognostic (5.89e-2)" "potential prognostic unfavorable (7.93e-4)" "unprognostic (5.02e-2)" RMDN2 "FAM82A, FAM82A1, FLJ32954, RMD2" ENSG00000115841 "Regulator of microtubule dynamics 2" Q96LZ7 2 37923187-38067142 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 40.0" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 327.4;Early spermatids: 255.0;Late primary spermatocytes: 212.1;Late spermatids: 240.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Kidney - Fibroblasts, Spleen - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "HPA034705, HPA034706" Enhanced Supported "Golgi apparatus,Mitotic spindle,Cytosol" Yes No "Cluster 2: Dendritic cells - Unknown function" "Cluster 47: Testis - Mixed function" "Cluster 34: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 19 "Mitotic spindle, Cytosol" "Golgi apparatus" "HPA034705: , HPA034706: " "unprognostic (1.82e-1)" "unprognostic (3.03e-1)" "unprognostic (1.68e-1)" "unprognostic (1.64e-1)" "unprognostic (1.44e-1)" "unprognostic (3.31e-3)" "unprognostic (2.08e-2)" "unprognostic (2.32e-1)" "unprognostic (9.06e-2)" "potential prognostic favorable (1.98e-7)" "unprognostic (2.70e-3)" "potential prognostic favorable (2.51e-4)" "unprognostic (1.23e-2)" "potential prognostic favorable (9.16e-4)" "unprognostic (4.30e-2)" "unprognostic (2.38e-2)" "unprognostic (1.31e-1)" "unprognostic (5.43e-2)" "unprognostic (1.60e-2)" "unprognostic (1.98e-2)" "unprognostic (3.03e-1)" "unprognostic (4.84e-2)" "unprognostic (8.15e-2)" "unprognostic (2.45e-3)" "unprognostic (2.45e-2)" "unprognostic (1.21e-2)" "unprognostic (8.25e-2)" "unprognostic (3.47e-2)" "unprognostic (3.14e-2)" RMDN3 "FAM82A2, FAM82C, FLJ10579, PTPIP51, RMD3" ENSG00000137824 "Regulator of microtubule dynamics 3" Q96TC7 15 40735884-40755851 "Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Differentiation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009975, HPA074840" Supported Enhanced "Cytokinetic bridge,Mitochondria" Yes No 22000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 27: Non-specific - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 53 Mitochondria "Cytokinetic bridge" "HPA009975: , HPA074840: " "unprognostic (4.23e-2)" "unprognostic (3.21e-2)" "unprognostic (9.02e-2)" "unprognostic (7.21e-2)" "unprognostic (1.34e-1)" "unprognostic (2.67e-2)" "unprognostic (1.29e-1)" "unprognostic (1.66e-3)" "unprognostic (2.95e-1)" "potential prognostic favorable (2.25e-10)" "unprognostic (1.60e-3)" "unprognostic (1.17e-1)" "unprognostic (7.85e-2)" "unprognostic (1.03e-1)" "unprognostic (2.51e-1)" "unprognostic (4.09e-2)" "unprognostic (8.01e-2)" "unprognostic (9.33e-2)" "unprognostic (3.11e-1)" "unprognostic (1.16e-3)" "unprognostic (8.79e-2)" "unprognostic (8.81e-3)" "unprognostic (4.81e-1)" "unprognostic (3.02e-2)" "unprognostic (6.77e-2)" "unprognostic (3.71e-2)" "unprognostic (3.58e-1)" "unprognostic (6.95e-2)" "unprognostic (9.02e-2)" RMI1 "BLAP75, C9orf76, FLJ12888" ENSG00000178966 "RecQ mediated genome instability 1" Q9H9A7 9 83980798-84004074 "Essential proteins, Predicted intracellular proteins" "DNA replication" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 76.2;Late spermatids: 80.8;Monocyte progenitors: 71.3;Respiratory deuterosomal cells: 79.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021661 Supported "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 35: Neutrophils - Protein binding" "Cluster 61: Non-specific - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Cell proliferation" 17 "Nucleoplasm, Nuclear bodies" "HPA021661: " "unprognostic (1.77e-1)" "unprognostic (5.22e-2)" "unprognostic (4.05e-2)" "unprognostic (7.02e-3)" "unprognostic (1.89e-1)" "unprognostic (6.07e-2)" "unprognostic (1.66e-1)" "unprognostic (4.38e-1)" "unprognostic (5.24e-2)" "potential prognostic unfavorable (2.87e-4)" "potential prognostic favorable (7.60e-5)" "unprognostic (6.37e-2)" "unprognostic (1.82e-1)" "validated prognostic unfavorable (9.39e-4)" "validated prognostic unfavorable (6.33e-4)" "unprognostic (4.92e-2)" "unprognostic (5.08e-2)" "unprognostic (1.70e-1)" "unprognostic (4.81e-2)" "unprognostic (3.54e-1)" "unprognostic (1.31e-1)" "unprognostic (7.03e-2)" "unprognostic (7.73e-2)" "unprognostic (1.81e-1)" "unprognostic (4.66e-3)" "unprognostic (6.39e-2)" "unprognostic (1.61e-2)" "unprognostic (3.48e-3)" "unprognostic (2.58e-1)" "unprognostic (8.41e-2)" "unprognostic (1.18e-1)" RMI2 "BLAP18, C16orf75, MGC24665" ENSG00000175643 "RecQ mediated genome instability 2" Q96E14 16 11249619-11381662 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "DNA replication" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 34.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 150.6;Differentiating spermatogonia: 68.3;Early primary spermatocytes: 102.2;Early spermatids: 180.5;Late spermatids: 280.3;Migrating cytotrophoblasts: 108.9;Undifferentiated spermatogonia: 79.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "memory B-cell: 4.2" "Group enriched" "Detected in many" 6 "B-cells: 4.2;T-cells: 1.4" "Low cancer specificity" "Detected in all" "Lung - Mitotic cells (Lung), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA040995 Uncertain Supported "Nuclear speckles,Cytosol" NA Yes "Cluster 43: Non-specific - Transcription & Translation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 51: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 8 "Nuclear speckles" Cytosol "HPA040995: " "unprognostic (1.88e-1)" "unprognostic (2.98e-1)" "unprognostic (7.63e-3)" "unprognostic (1.39e-1)" "unprognostic (1.75e-1)" "unprognostic (7.82e-3)" "unprognostic (8.70e-2)" "unprognostic (2.26e-3)" "unprognostic (2.05e-1)" "unprognostic (1.11e-1)" "unprognostic (8.39e-2)" "unprognostic (1.19e-3)" "validated prognostic unfavorable (3.66e-6)" "validated prognostic unfavorable (8.79e-6)" "unprognostic (5.10e-3)" "unprognostic (1.32e-2)" "unprognostic (1.12e-2)" "unprognostic (7.39e-2)" "unprognostic (2.95e-1)" "unprognostic (1.56e-1)" "unprognostic (4.69e-3)" "potential prognostic unfavorable (8.51e-5)" "unprognostic (2.71e-1)" "unprognostic (1.90e-2)" "unprognostic (1.55e-1)" "unprognostic (1.62e-1)" "unprognostic (1.19e-1)" "unprognostic (7.53e-2)" "unprognostic (4.42e-3)" "unprognostic (6.26e-2)" RMND1 "bA351K16.3, C6orf96, FLJ20627, RMD1" ENSG00000155906 "Required for meiotic nuclear division 1 homolog" Q9NWS8 6 151398898-151452158 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protein biosynthesis" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031397, HPA031398, HPA031399" Approved Supported Mitochondria NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 76: Non-specific - Metabolism" "Cluster 16: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 11 Mitochondria "HPA031397: , HPA031398: , HPA031399: " "unprognostic (5.86e-2)" "unprognostic (1.86e-2)" "unprognostic (1.01e-2)" "unprognostic (1.19e-2)" "unprognostic (3.33e-1)" "unprognostic (1.65e-1)" "unprognostic (6.19e-2)" "unprognostic (4.59e-3)" "unprognostic (3.71e-2)" "unprognostic (3.35e-2)" "potential prognostic favorable (9.34e-8)" "unprognostic (6.34e-2)" "unprognostic (1.24e-1)" "unprognostic (5.07e-3)" "unprognostic (3.78e-2)" "unprognostic (2.19e-3)" "unprognostic (3.23e-2)" "unprognostic (1.20e-1)" "unprognostic (2.31e-1)" "unprognostic (5.67e-2)" "unprognostic (1.68e-1)" "unprognostic (4.43e-2)" "unprognostic (1.63e-1)" "unprognostic (8.11e-2)" "unprognostic (1.54e-2)" "unprognostic (4.08e-1)" "unprognostic (7.35e-2)" "unprognostic (2.95e-1)" "unprognostic (4.60e-1)" "unprognostic (7.22e-2)" "unprognostic (7.36e-2)" RMND5A "FLJ13910, GID2, GID2A, p44CTLH, RMD5" ENSG00000153561 "Required for meiotic nuclear division 5 homolog A" Q9H871 2 86720291-86778041 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 488.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046795, HPA060843" Uncertain Supported Nucleoplasm NA NA "Cluster 41: Basophils - Unknown function" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 35: Non-specific - DNA binding" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 75 Nucleoplasm "HPA046795: , HPA060843: " "unprognostic (1.26e-1)" "unprognostic (8.02e-2)" "unprognostic (7.14e-2)" "unprognostic (8.03e-2)" "unprognostic (2.34e-1)" "unprognostic (1.20e-1)" "unprognostic (7.70e-2)" "potential prognostic favorable (5.75e-5)" "unprognostic (8.38e-2)" "unprognostic (9.54e-2)" "validated prognostic favorable (9.94e-8)" "validated prognostic favorable (2.82e-4)" "unprognostic (4.88e-3)" "unprognostic (1.18e-1)" "unprognostic (6.67e-2)" "unprognostic (3.04e-2)" "unprognostic (2.52e-1)" "unprognostic (7.05e-2)" "potential prognostic favorable (6.64e-4)" "unprognostic (7.40e-2)" "unprognostic (3.18e-2)" "unprognostic (4.28e-3)" "unprognostic (4.04e-1)" "unprognostic (2.83e-1)" "unprognostic (3.25e-1)" "unprognostic (1.82e-1)" "unprognostic (1.32e-1)" "unprognostic (2.34e-2)" "unprognostic (1.09e-1)" "unprognostic (2.82e-1)" "unprognostic (2.23e-1)" RMND5B "FLJ22318, GID2, GID2B" ENSG00000145916 "Required for meiotic nuclear division 5 homolog B" Q96G75 5 178130996-178150568 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 168.2;Esophageal apical cells: 527.4;Late primary spermatocytes: 278.6;Late spermatids: 753.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047778 Uncertain NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 27: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 27 "HPA047778: " "unprognostic (4.23e-2)" "unprognostic (1.26e-1)" "unprognostic (8.92e-2)" "unprognostic (1.48e-1)" "unprognostic (1.94e-1)" "unprognostic (4.50e-1)" "unprognostic (3.67e-2)" "unprognostic (4.89e-2)" "unprognostic (1.21e-2)" "unprognostic (7.53e-2)" "potential prognostic favorable (2.79e-9)" "unprognostic (2.17e-2)" "potential prognostic favorable (2.28e-6)" "potential prognostic unfavorable (2.45e-4)" "unprognostic (9.00e-2)" "unprognostic (1.52e-1)" "unprognostic (1.16e-1)" "unprognostic (8.56e-2)" "unprognostic (2.54e-1)" "unprognostic (2.47e-1)" "unprognostic (2.33e-3)" "unprognostic (2.28e-2)" "unprognostic (1.33e-1)" "unprognostic (3.75e-1)" "unprognostic (1.26e-1)" "unprognostic (1.42e-3)" "unprognostic (4.62e-2)" "unprognostic (9.50e-2)" "unprognostic (1.55e-1)" "unprognostic (8.71e-2)" "unprognostic (3.18e-1)" RNASE1 "RAC1, RNS1" ENSG00000129538 "Ribonuclease A family member 1, pancreatic" P07998 14 20801228-20802855 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Endonuclease, Hydrolase, Lyase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "pancreas: 8599.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 1645.7;Alveolar cells type 2: 1736.4;Foveolar cells: 1836.7;Goblet cells: 570.9;Hofbauer cells: 3208.8;Macrophages: 1415.3;Retinal pigment epithelial cells: 2562.0;Transitional alveolar cells: 2328.2" "Cell type enhanced" "Detected in many" "endothelial cell: 294.3;oligodendrocyte: 446.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 9.7;myeloid DC: 20.3" "Group enriched" "Detected in many" 9 "dendritic cells: 20.3;monocytes: 9.7" "Cancer enhanced" "Detected in many" "Bile duct cancer: 78.8;pancreatic cancer: 57.9;skin cancer: 60.1" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Liver - Vascular endothelial cells, Minor Salivary Gland - Macrophages, Pancreas - Exocrine glandular cells, Skeletal muscle - Macrophages, Stomach - Gastric mucous cells, Testis - Sertoli cells, Thyroid gland - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA001140 Enhanced Approved Nucleoplasm,Vesicles "Secreted to digestive system" Enzyme NA NA 280000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 8: Pancreas - Proteolysis" "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 5 Vesicles Nucleoplasm "HPA001140: " "unprognostic (2.07e-1)" "unprognostic (6.52e-3)" "unprognostic (5.11e-1)" "unprognostic (1.12e-1)" "unprognostic (1.01e-1)" "unprognostic (6.47e-2)" "unprognostic (2.56e-3)" "unprognostic (5.30e-2)" "unprognostic (1.05e-1)" "unprognostic (1.87e-2)" "validated prognostic favorable (2.80e-4)" "validated prognostic favorable (1.02e-4)" "unprognostic (3.23e-1)" "unprognostic (1.22e-3)" "unprognostic (1.70e-1)" "potential prognostic favorable (3.07e-4)" "unprognostic (1.89e-1)" "unprognostic (1.66e-2)" "unprognostic (6.28e-2)" "unprognostic (5.67e-2)" "unprognostic (1.65e-1)" "unprognostic (1.38e-1)" "unprognostic (1.15e-2)" "unprognostic (3.46e-2)" "unprognostic (2.48e-3)" "unprognostic (1.68e-1)" "unprognostic (2.78e-2)" "unprognostic (1.14e-3)" "unprognostic (1.64e-1)" "unprognostic (6.00e-2)" "unprognostic (7.50e-2)" RNASE10 "RAH1, RNASE9" ENSG00000182545 "Ribonuclease A family member 10 (inactive)" Q5GAN6 14 20505537-20513884 "Predicted secreted proteins" "Cell adhesion, Fertilization" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 1.7;Distal convoluted tubule cells: 3.9;Early primary spermatocytes: 1.5;Loop of henle epithelial cells: 4.6;Mucous neck cells: 1.6;Papillary tip epithelial cells: 8.6;Proximal tubule cells: 2.0;Renal collecting duct intercalated cells: 4.0;Renal collecting duct principal cells: 12.6;Renal connecting tubule cells: 3.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 66.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Esophageal cancer: 3.4;head and neck cancer: 3.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA052593 Uncertain "Secreted - unknown location" "Cell adhesion" NA NA "Cluster 6: Non-specific - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 6 "HPA052593: " "unprognostic (2.37e-1)" "unprognostic (8.31e-2)" "unprognostic (4.94e-3)" "unprognostic (2.44e-1)" "potential prognostic unfavorable (2.26e-6)" "unprognostic (1.05e-2)" "unprognostic (1.30e-1)" "unprognostic (8.05e-2)" "unprognostic (2.36e-2)" "unprognostic (5.65e-3)" "unprognostic (2.19e-2)" "unprognostic (5.17e-2)" "potential prognostic unfavorable (9.50e-4)" "unprognostic (7.22e-2)" "unprognostic (1.89e-2)" "unprognostic (1.10e-1)" "unprognostic (2.32e-1)" "unprognostic (8.75e-3)" "unprognostic (1.49e-1)" "unprognostic (6.57e-2)" "unprognostic (3.55e-2)" "unprognostic (1.50e-2)" "unprognostic (1.54e-2)" "unprognostic (1.70e-2)" "unprognostic (1.03e-1)" "unprognostic (1.60e-1)" "unprognostic (1.39e-2)" "unprognostic (1.82e-1)" RNASE11 "C14orf6, RAJ1" ENSG00000173464 "Ribonuclease A family member 11 (inactive)" Q8TAA1 14 20582892-20609884 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "epididymis: 622.3" "Group enriched" "Detected in some" 6 "Early spermatids: 24.5;Epididymal principal cells: 18.8;Late spermatids: 53.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" HPA003724 Uncertain "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" "HPA003724: " RNASE12 RAI1 ENSG00000258436 "Ribonuclease A family member 12 (inactive)" Q5GAN4 14 20590073-20591376 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 284 "epididymis: 656.9" "Group enriched" "Detected in some" 5 "Epididymal clear cells: 2.0;Epididymal principal cells: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA044175, HPA059465" Enhanced "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" "HPA044175: , HPA059465: " RNASE13 RAL1 ENSG00000206150 "Ribonuclease A family member 13 (inactive)" Q5GAN3 14 21032818-21034807 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 102 "epididymis: 289.8" "Cell type enriched" "Detected in single" 27 "Epididymal principal cells: 5.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Testis - Late spermatids" "Not detected" "Not detected" "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 15: Kidney cancer - Membrane components" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" RNASE2 "EDN, RAF3, RNS2" ENSG00000169385 "Ribonuclease A family member 2" P10153 14 20955487-20956436 "Enzymes, Plasma proteins, Predicted secreted proteins" Chemotaxis "Endonuclease, Hydrolase, Lyase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 48 "bone marrow: 1614.8" "Group enriched" "Detected in some" 13 "Monocyte progenitors: 1013.4;monocytes: 268.2;Neutrophil progenitors: 591.6" "Cell type enriched" "Detected in single" 5 "central nervous system macrophage: 3.3" "Cancer enriched" "Detected in many" 7 "Glioblastoma Multiforme (TCGA): 27.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 459.4;eosinophil: 1355.1" "Lineage enriched" "Detected in many" 7 "granulocytes: 1355.1" "Cancer enriched" "Detected in single" 210 "Leukemia: 160.0" "Adipose subcutaneous - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Lung - Neutrophils_2, Prostate - Macrophages, Spleen - Neutrophils_1, Stomach - Macrophages, Thyroid gland - Macrophages" "Not detected" "Not detected" HPA044983 Enhanced "Secreted to blood" Enzyme NA NA 27000000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 15: Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 1 "HPA044983: " "unprognostic (2.54e-1)" "unprognostic (8.04e-2)" "unprognostic (6.93e-2)" "unprognostic (1.25e-1)" "unprognostic (9.64e-2)" "unprognostic (7.99e-2)" "unprognostic (6.81e-3)" "unprognostic (5.03e-2)" "unprognostic (9.51e-2)" "potential prognostic unfavorable (2.10e-6)" "unprognostic (7.01e-3)" "unprognostic (2.21e-1)" "potential prognostic unfavorable (5.59e-4)" "unprognostic (1.55e-2)" "unprognostic (3.76e-2)" "unprognostic (1.60e-3)" "unprognostic (5.62e-3)" "unprognostic (1.39e-3)" "unprognostic (1.08e-2)" "unprognostic (1.34e-1)" "unprognostic (8.22e-3)" "unprognostic (2.28e-1)" "unprognostic (2.04e-1)" "unprognostic (2.21e-1)" "unprognostic (1.98e-1)" "unprognostic (4.38e-3)" "unprognostic (1.21e-2)" "unprognostic (1.37e-2)" "unprognostic (8.69e-2)" RNASE3 "ECP, RAF1, RNS3" ENSG00000169397 "Ribonuclease A family member 3" P12724 14 20891385-20892348 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 95 "bone marrow: 856.4" "Group enriched" "Detected in some" 9 "Monocyte progenitors: 98.5;Neutrophil progenitors: 283.9" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 8 "Glioblastoma Multiforme (TCGA): 4.2" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 20 "eosinophil: 307.0" "Lineage enriched" "Detected in many" 20 "granulocytes: 307.0" "Cancer enriched" "Detected in single" 42 "Leukemia: 22.3" "Lung - Neutrophils_1, Spleen - Neutrophils_1, Testis - Late spermatids" HPA056183 Enhanced "Secreted to blood" Enzyme NA NA 4200000 69000 "Cluster 29: Non-specific - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 22: Non-specific - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" "HPA056183: " "unprognostic (2.10e-2)" "unprognostic (3.29e-2)" RNASE4 RAB1 ENSG00000258818 "Ribonuclease A family member 4" P34096 14 20684560-20701216 "Plasma proteins, Predicted secreted proteins" "Antibiotic, Antimicrobial, Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "liver: 447.2" "Cell type enhanced" "Detected in many" "Colonocytes: 36.1;Enteric stem cells: 41.8;Enterocytes: 36.6;Epididymal efferent duct absorptive cells: 87.3;Foveolar cells: 96.5;Gastric chief cells: 122.3;Goblet cells: 103.5;Hepatocytes: 57.4;Mucous neck cells: 64.1;Neuroendocrine cells: 73.1;Paneth cells: 42.5;Parietal cells: 84.9" "Cell type enhanced" "Detected in some" "fibroblast: 14.6;pericyte: 19.5;vascular associated smooth muscle cell: 26.1" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 108.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 24.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Fibroblasts, Spleen - Fibroblasts_2, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" Enzyme NA NA 110000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 39: Astrocytes - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 70: Intestinal goblet cells - Mucin production" 1 "unprognostic (2.07e-1)" "unprognostic (9.64e-2)" "unprognostic (3.84e-2)" "unprognostic (4.07e-2)" "unprognostic (1.72e-2)" "unprognostic (5.16e-1)" "unprognostic (1.06e-2)" "potential prognostic unfavorable (1.35e-4)" "unprognostic (9.38e-2)" "unprognostic (1.15e-1)" "validated prognostic favorable (1.02e-5)" "validated prognostic favorable (1.59e-4)" "unprognostic (9.82e-3)" "validated prognostic favorable (5.72e-5)" "validated prognostic favorable (6.12e-4)" "unprognostic (8.68e-2)" "unprognostic (1.28e-1)" "unprognostic (3.67e-2)" "unprognostic (3.46e-2)" "unprognostic (1.05e-1)" "unprognostic (2.57e-1)" "unprognostic (6.95e-2)" "unprognostic (4.11e-2)" "unprognostic (1.51e-1)" "unprognostic (1.19e-1)" "potential prognostic unfavorable (5.02e-4)" "unprognostic (3.53e-1)" "unprognostic (4.91e-3)" "unprognostic (2.50e-1)" "unprognostic (6.54e-2)" "unprognostic (5.67e-2)" RNASE6 "RAD1, RNaseK6, RNS6" ENSG00000169413 "Ribonuclease A family member k6" Q93091 14 20781268-20782467 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 103.5" "Cell type enhanced" "Detected in some" "B-cells: 78.8;cDC: 216.1;Hofbauer cells: 288.5;Kupffer cells: 594.4;Macrophages: 238.6;Monocyte progenitors: 125.7;monocytes: 241.3;Neutrophils: 171.2;pDCs: 256.2" "Cell type enriched" "Detected in some" 11 "central nervous system macrophage: 35.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 1241.7" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Leukemia: 21.5;lymphoma: 7.2;Myeloma: 9.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA000698 Approved "Secreted to blood" Enzyme NA NA 410000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 82: Dendritic cells - Antigen presentation" "HPA000698: " "unprognostic (2.53e-1)" "unprognostic (7.36e-2)" "unprognostic (1.26e-1)" "unprognostic (8.10e-3)" "unprognostic (1.94e-1)" "unprognostic (3.56e-1)" "unprognostic (1.09e-1)" "unprognostic (1.79e-1)" "unprognostic (1.65e-2)" "unprognostic (1.27e-1)" "unprognostic (5.37e-3)" "unprognostic (1.72e-1)" "unprognostic (1.97e-1)" "unprognostic (7.31e-2)" "unprognostic (2.86e-1)" "unprognostic (2.80e-2)" "unprognostic (1.03e-2)" "unprognostic (3.48e-2)" "unprognostic (4.34e-3)" "unprognostic (5.05e-2)" "unprognostic (7.48e-2)" "unprognostic (1.27e-1)" "unprognostic (2.10e-1)" "unprognostic (3.05e-1)" "unprognostic (3.93e-3)" "unprognostic (5.26e-2)" "unprognostic (4.76e-1)" "unprognostic (2.51e-2)" "potential prognostic unfavorable (8.51e-4)" "unprognostic (9.90e-3)" "unprognostic (2.67e-2)" RNASE7 RAE1 ENSG00000165799 "Ribonuclease A family member 7" Q9H1E1 14 21042316-21044234 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 70.4;lymphoid tissue: 22.6;skin 1: 26.3" "Cell type enriched" "Detected in some" 7 "Esophageal apical cells: 340.6" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Head and Neck Squamous Cell Carcinoma (TCGA): 26.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 4.3;head and neck cancer: 10.2" "Breast - Breast myoepithelial cells, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (granular)" "HPA005690, CAB062560, CAB068225" Enhanced "Secreted in other tissues" Enzyme NA NA 5100000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 84: Apical squamous epithelium - Cornification" 16 "CAB062560: , CAB068225: , HPA005690: " "unprognostic (9.03e-3)" "unprognostic (1.17e-1)" "unprognostic (5.05e-2)" "unprognostic (4.27e-2)" "unprognostic (2.23e-1)" "unprognostic (1.23e-2)" "unprognostic (1.34e-1)" "unprognostic (2.20e-1)" RNASE8 RAE2 ENSG00000173431 "Ribonuclease A family member 8" Q8TDE3 14 21057822-21058455 "Predicted secreted proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 229 "salivary gland: 51.7" "Cell type enriched" "Detected in single" 12 "Salivary acinar cells: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Minor Salivary Gland - Minor salivary glandular cells" "Secreted to digestive system" Enzyme NA NA "Cluster 82: Salivary gland - Secretion" "Cluster 38: Secretory epithelial cells - Exocrine secretion" RNASE9 "h461, RAK1" ENSG00000188655 "Ribonuclease A family member 9 (inactive)" P60153 14 20556093-20560931 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 931 "epididymis: 93.0" "Cell type enriched" "Detected in some" 70 "Epididymal principal cells: 143.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" RNASEH1 ENSG00000171865 "Ribonuclease H1" O60930 2 3541430-3558333 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Disease variant, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 2.8;Loop of henle epithelial cells: 3.8;Papillary tip epithelial cells: 2.6;Podocytes: 2.8;Proximal tubule cells: 3.4;Renal collecting duct intercalated cells: 3.6;Renal collecting duct principal cells: 3.6;Renal connecting tubule cells: 3.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034817, HPA043037" Uncertain Approved Nucleoplasm,Cytosol "Intracellular and membrane" Enzyme NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 105: Non-specific - Mixed function" 9 "Nucleoplasm, Cytosol" "HPA034817: , HPA043037: " "unprognostic (8.89e-2)" "unprognostic (6.03e-2)" "unprognostic (6.32e-2)" "unprognostic (2.27e-2)" "unprognostic (9.93e-2)" "unprognostic (1.14e-1)" "unprognostic (3.37e-1)" "unprognostic (8.75e-2)" "unprognostic (8.57e-2)" "unprognostic (4.15e-3)" "unprognostic (5.20e-2)" "unprognostic (3.07e-1)" "unprognostic (2.94e-2)" "unprognostic (1.41e-3)" "potential prognostic unfavorable (6.97e-4)" "unprognostic (9.12e-3)" "unprognostic (2.02e-2)" "unprognostic (7.66e-2)" "unprognostic (1.58e-1)" "unprognostic (9.55e-2)" "unprognostic (4.28e-2)" "unprognostic (6.55e-2)" "unprognostic (2.83e-2)" "unprognostic (1.93e-1)" "unprognostic (1.50e-1)" "unprognostic (1.81e-1)" "unprognostic (1.10e-1)" "unprognostic (1.01e-1)" "unprognostic (2.23e-1)" "unprognostic (7.56e-3)" "unprognostic (3.55e-1)" RNASEH2A "AGS4, RNASEHI, RNHIA, RNHL" ENSG00000104889 "Ribonuclease H2 subunit A" O75792 19 12806584-12813640 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Aicardi-Goutieres syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 7.1;Differentiating spermatogonia: 7.1;Enteric stem cells: 8.7;Enteric transient amplifying cells: 16.7;Erythrocyte progenitors: 8.7;Extravillous trophoblasts: 11.6;Gastric progenitor cells: 7.7;Megakaryocyte progenitors: 7.2;Megakaryocytes: 12.4;Migrating cytotrophoblasts: 9.3;Paneth cells: 11.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042692 Enhanced Nucleoplasm,Cytosol No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 30: White matter - Myelination" "Cluster 23: Non-specific - Transcription" "Cluster 27: Non-specific - Cell proliferation" 16 Nucleoplasm Cytosol "HPA042692: " "unprognostic (2.14e-3)" "unprognostic (2.47e-2)" "unprognostic (2.96e-1)" "potential prognostic favorable (3.94e-4)" "unprognostic (2.21e-3)" "unprognostic (1.85e-2)" "unprognostic (1.31e-1)" "unprognostic (1.56e-1)" "unprognostic (1.87e-1)" "unprognostic (5.20e-3)" "unprognostic (4.11e-2)" "unprognostic (1.19e-2)" "potential prognostic unfavorable (2.17e-5)" "validated prognostic unfavorable (3.49e-5)" "validated prognostic unfavorable (2.52e-7)" "unprognostic (2.23e-3)" "potential prognostic unfavorable (8.73e-4)" "unprognostic (3.65e-3)" "unprognostic (2.11e-2)" "potential prognostic favorable (2.17e-4)" "unprognostic (3.57e-1)" "unprognostic (4.80e-3)" "unprognostic (9.59e-2)" "unprognostic (3.33e-2)" "unprognostic (2.20e-2)" "unprognostic (2.32e-2)" "unprognostic (3.29e-1)" "unprognostic (2.44e-2)" "unprognostic (8.06e-2)" "unprognostic (1.06e-1)" "unprognostic (1.49e-1)" RNASEH2B "AGS2, DLEU8, FLJ11712" ENSG00000136104 "Ribonuclease H2 subunit B" Q5TBB1 13 50909747-51024120 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Aicardi-Goutieres syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 123.4" "Cell type enhanced" "Detected in all" "Erythrocyte progenitors: 209.2;Thymocytes: 269.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040084, HPA041469" Approved Enhanced Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 80: Thymus - Adaptive immune response" "Cluster 34: Non-specific - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 8 Nucleoplasm "HPA040084: , HPA041469: " "unprognostic (4.89e-2)" "unprognostic (1.54e-1)" "unprognostic (6.87e-2)" "unprognostic (1.64e-1)" "unprognostic (2.96e-2)" "unprognostic (3.33e-2)" "unprognostic (3.33e-1)" "potential prognostic favorable (9.31e-4)" "unprognostic (1.03e-1)" "unprognostic (1.84e-1)" "unprognostic (1.28e-3)" "unprognostic (1.23e-1)" "unprognostic (1.11e-1)" "unprognostic (8.24e-2)" "unprognostic (2.46e-2)" "unprognostic (2.62e-1)" "unprognostic (1.58e-2)" "unprognostic (2.05e-1)" "unprognostic (5.12e-2)" "unprognostic (7.43e-2)" "unprognostic (1.26e-2)" "unprognostic (2.40e-1)" "unprognostic (8.52e-2)" "unprognostic (1.32e-1)" "unprognostic (3.82e-2)" "unprognostic (8.06e-2)" "unprognostic (3.54e-2)" "unprognostic (2.42e-1)" "unprognostic (1.19e-1)" "unprognostic (1.73e-1)" "unprognostic (2.64e-1)" RNASEH2C "AGS3, AYP1" ENSG00000172922 "Ribonuclease H2 subunit C" Q8TDP1 11 65714005-65720818 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Aicardi-Goutieres syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 231.0;Syncytiotrophoblasts: 249.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065375 Supported Approved Nucleoplasm NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 14 Nucleoplasm "HPA065375: " "unprognostic (1.38e-1)" "unprognostic (8.28e-3)" "unprognostic (1.68e-1)" "unprognostic (1.41e-1)" "unprognostic (4.01e-3)" "unprognostic (9.68e-2)" "unprognostic (3.87e-1)" "unprognostic (6.44e-2)" "unprognostic (1.15e-1)" "potential prognostic unfavorable (8.83e-5)" "unprognostic (4.78e-2)" "unprognostic (7.18e-2)" "unprognostic (4.73e-1)" "potential prognostic unfavorable (9.13e-4)" "unprognostic (4.20e-2)" "unprognostic (1.67e-2)" "unprognostic (5.75e-3)" "unprognostic (2.47e-1)" "unprognostic (1.16e-2)" "unprognostic (7.43e-2)" "unprognostic (1.19e-1)" "unprognostic (1.09e-2)" "unprognostic (2.17e-1)" "unprognostic (1.22e-1)" "unprognostic (4.15e-2)" "unprognostic (1.66e-1)" "unprognostic (1.04e-1)" "unprognostic (1.18e-1)" "unprognostic (1.46e-1)" "unprognostic (3.30e-1)" "unprognostic (5.72e-2)" RNASEK MGC71993 ENSG00000219200 "Ribonuclease K" Q6P5S7 17 7012417-7014532 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Endocytosis, Hydrogen ion transport, Ion transport, Transport" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 41.3;Bergmann glia: 48.2;Brain excitatory neurons: 91.1;Brain inhibitory neurons: 94.5;Ependymal cells: 43.4;Microglia: 81.9;Oligodendrocyte progenitor cells: 63.4;Oligodendrocytes: 86.9;Other brain neurons: 193.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044708 Uncertain NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 42: Non-specific - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" 22 "HPA044708: " "unprognostic (9.96e-2)" "unprognostic (7.26e-2)" "unprognostic (7.88e-2)" "unprognostic (2.55e-2)" "unprognostic (1.58e-1)" "unprognostic (1.85e-1)" "unprognostic (2.49e-2)" "unprognostic (6.54e-3)" "unprognostic (6.78e-2)" "unprognostic (1.61e-1)" "unprognostic (1.41e-3)" "unprognostic (9.42e-2)" "unprognostic (1.49e-2)" "unprognostic (6.18e-3)" "unprognostic (2.46e-1)" "unprognostic (9.60e-2)" "unprognostic (3.79e-1)" "unprognostic (9.11e-2)" "unprognostic (3.41e-1)" "unprognostic (1.13e-2)" "unprognostic (1.35e-1)" "potential prognostic favorable (2.86e-5)" "unprognostic (2.30e-1)" "unprognostic (1.76e-1)" "unprognostic (7.24e-3)" "unprognostic (9.27e-2)" "unprognostic (1.67e-2)" "unprognostic (2.44e-1)" "unprognostic (1.15e-1)" "unprognostic (1.36e-1)" "unprognostic (2.00e-2)" RNASEK-C17orf49 ENSG00000161939 "RNASEK-C17orf49 readthrough" 17 7012635-7017520 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Colonocytes: 4.0;Enterocytes: 4.0;Epididymal clear cells: 14.3;Epididymal efferent duct absorptive cells: 3.6;Epididymal efferent duct ciliated cells: 4.6;Epididymal principal cells: 4.0;Gastric chief cells: 6.6;Neuroendocrine cells: 3.3;Paneth cells: 3.9;Parietal cells: 5.3" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 6.4" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "HPA022961, HPA024457" Uncertain Uncertain Nucleoplasm,Cytosol NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 42: Non-specific - Unknown function" "Cluster 15: Non-specific - Protein processing" 10 Nucleoplasm Cytosol "HPA022961: , HPA024457: " "unprognostic (5.23e-1)" "unprognostic (4.39e-1)" "unprognostic (1.37e-1)" "unprognostic (2.56e-1)" "unprognostic (3.03e-2)" "unprognostic (1.12e-2)" "unprognostic (4.98e-1)" "unprognostic (6.77e-1)" RNASEL "PRCA1, RNS4" ENSG00000135828 "Ribonuclease L" Q05823 1 182573634-182589256 "Enzymes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense" "Endonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 50.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002633, CAB010906, HPA046758" Approved Supported Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 61: Non-specific - Transcription" "Cluster 9: Non-specific - Receptor signaling" "Cluster 6: Leukemia - Signal transduction" "Cluster 24: Neutrophils - Innate immunity signal integration" 4 Cytosol "CAB010906: , HPA002633: , HPA046758: " "unprognostic (2.00e-2)" "unprognostic (2.54e-1)" "unprognostic (7.74e-3)" "unprognostic (2.86e-1)" "unprognostic (1.67e-3)" "unprognostic (1.07e-1)" "unprognostic (1.92e-1)" "unprognostic (2.35e-3)" "unprognostic (1.32e-1)" "unprognostic (2.90e-1)" "potential prognostic favorable (4.31e-5)" "unprognostic (7.14e-3)" "unprognostic (3.02e-1)" "unprognostic (8.83e-2)" "unprognostic (3.27e-2)" "unprognostic (9.05e-2)" "unprognostic (4.47e-2)" "unprognostic (2.23e-1)" "unprognostic (1.51e-1)" "unprognostic (1.57e-2)" "unprognostic (2.03e-2)" "unprognostic (1.94e-1)" "unprognostic (2.12e-1)" "unprognostic (3.58e-1)" "unprognostic (6.23e-2)" "unprognostic (8.49e-2)" "unprognostic (2.44e-2)" "unprognostic (6.21e-2)" "unprognostic (1.20e-1)" "unprognostic (2.69e-1)" "unprognostic (2.03e-1)" RNASET2 "bA514O12.3, FLJ10907, RNASE6PL" ENSG00000026297 "Ribonuclease T2" O00584 6 166922113-166957191 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Endonuclease, Hydrolase, Lyase, Nuclease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 361.7;Endometrial luminal cells: 720.9;Epididymal efferent duct absorptive cells: 331.5;Fallopian secretory cells: 266.5;Hofbauer cells: 254.4;Kupffer cells: 330.0;Macrophages: 224.6;Neutrophils: 274.9;pDCs: 353.1" "Cell type enriched" "Detected in all" 7 "central nervous system macrophage: 234.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney cancer: 182.0" "Adipose subcutaneous - Macrophages, Adrenal gland - Macrophages, Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Fibroblasts, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029013, HPA066509" Approved "Secreted to blood" Immunity NA NA 4700000 "Cluster 25: Non-specific - Unknown function" "Cluster 22: Epididymis - Mixed function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 4 "HPA029013: , HPA066509: " "unprognostic (4.73e-2)" "unprognostic (2.71e-1)" "unprognostic (2.59e-2)" "unprognostic (1.81e-1)" "unprognostic (1.34e-1)" "potential prognostic favorable (8.82e-4)" "unprognostic (3.64e-2)" "unprognostic (4.03e-2)" "unprognostic (2.90e-1)" "unprognostic (7.51e-2)" "potential prognostic unfavorable (5.23e-5)" "unprognostic (2.27e-2)" "unprognostic (3.28e-2)" "unprognostic (9.35e-3)" "unprognostic (2.53e-2)" "unprognostic (4.99e-2)" "unprognostic (8.47e-2)" "unprognostic (1.80e-1)" "unprognostic (1.22e-1)" "unprognostic (5.21e-2)" "unprognostic (3.50e-1)" "unprognostic (8.10e-3)" "unprognostic (1.03e-1)" "unprognostic (2.75e-3)" "unprognostic (4.14e-2)" "unprognostic (1.45e-1)" "unprognostic (7.76e-2)" "unprognostic (1.86e-1)" "unprognostic (1.74e-1)" "unprognostic (9.52e-2)" "unprognostic (1.39e-1)" RND1 "ARHS, Rho6, RHOS" ENSG00000172602 "Rho family GTPase 1" Q92730 12 48857145-48865870 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 48.8;liver: 119.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 72.2;Breast hormone-responsive cells: 74.8;Epididymal clear cells: 49.0;Epididymal efferent duct absorptive cells: 127.4;Pancreatic acinar cells: 45.3;Salivary acinar cells: 87.9;Transitional alveolar cells: 52.2;Vascular endothelial cells: 144.6" "Cell type enhanced" "Detected in many" "endothelial cell: 39.6" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 39.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 19.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077800 Supported "Vesicles,Plasma membrane,Actin filaments" NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 53: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 15 "Vesicles, Plasma membrane, Actin filaments" "HPA077800: " "unprognostic (5.59e-2)" "unprognostic (3.18e-1)" "unprognostic (3.00e-1)" "potential prognostic unfavorable (2.89e-4)" "unprognostic (1.48e-1)" "unprognostic (1.29e-1)" "unprognostic (7.90e-2)" "unprognostic (9.69e-2)" "unprognostic (1.66e-2)" "unprognostic (7.73e-2)" "unprognostic (2.65e-3)" "unprognostic (7.93e-3)" "unprognostic (3.95e-2)" "unprognostic (1.95e-2)" "unprognostic (1.93e-1)" "unprognostic (1.07e-2)" "unprognostic (2.38e-2)" "unprognostic (4.23e-2)" "unprognostic (9.66e-2)" "unprognostic (1.65e-1)" "unprognostic (4.02e-1)" "unprognostic (1.27e-1)" "unprognostic (1.02e-1)" "unprognostic (1.50e-1)" "unprognostic (7.60e-2)" "unprognostic (1.01e-1)" "unprognostic (4.06e-3)" "unprognostic (1.34e-1)" "unprognostic (1.76e-2)" "unprognostic (8.33e-2)" RND2 "ARHN, Rho7, RhoN" ENSG00000108830 "Rho family GTPase 2" P52198 17 43025231-43032041 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 95.2;testis: 35.5" "Cell type enriched" "Detected in many" 7 "Late spermatids: 1019.4" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 80.1" "Group enriched" "Detected in many" 5 "Glioblastoma Multiforme (TCGA): 71.9;Testicular Germ Cell Tumor (TCGA): 19.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 8.1" "Adipose subcutaneous - Smooth muscle cells, Stomach - Fibroblasts, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077757 Approved NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 9 "HPA077757: " "unprognostic (8.93e-2)" "unprognostic (3.06e-2)" "unprognostic (6.16e-2)" "unprognostic (3.47e-2)" "unprognostic (1.02e-1)" "unprognostic (3.81e-3)" "unprognostic (7.13e-3)" "unprognostic (4.88e-2)" "unprognostic (3.92e-3)" "unprognostic (1.59e-2)" "unprognostic (3.35e-3)" "unprognostic (2.09e-1)" "unprognostic (9.13e-2)" "potential prognostic favorable (1.64e-4)" "unprognostic (2.11e-1)" "unprognostic (1.72e-1)" "potential prognostic favorable (2.34e-4)" "unprognostic (1.37e-1)" "unprognostic (1.93e-1)" "unprognostic (2.78e-1)" "unprognostic (1.13e-1)" "unprognostic (6.20e-2)" RND3 "ARHE, Rho8, RhoE" ENSG00000115963 "Rho family GTPase 3" P61587 2 150468195-150539011 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 146.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 1448.9;Endometrial luminal cells: 472.7;Endometrial secretory cells: 744.1;Endometrial stromal cells: 546.4;Epididymal basal cells: 473.8;Esophageal apical cells: 796.1;Ocular epithelial cells: 949.7;Suprabasal keratinocytes: 814.5;Urothelial cells: 599.3" "Cell type enhanced" "Detected in many" "fibroblast: 180.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Colon - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060504 Uncertain NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 29: Forebrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 100: Stratified epithelial cells - Barrier functions" 15 "HPA060504: " "unprognostic (8.24e-2)" "unprognostic (3.84e-2)" "unprognostic (1.37e-1)" "unprognostic (1.35e-2)" "unprognostic (2.23e-1)" "unprognostic (1.71e-1)" "unprognostic (2.53e-3)" "unprognostic (3.12e-1)" "unprognostic (3.82e-2)" "unprognostic (2.10e-1)" "unprognostic (6.16e-2)" "unprognostic (2.20e-1)" "unprognostic (7.94e-3)" "unprognostic (1.07e-1)" "unprognostic (6.93e-3)" "potential prognostic unfavorable (2.45e-4)" "unprognostic (1.48e-1)" "unprognostic (2.65e-1)" "unprognostic (1.04e-1)" "unprognostic (3.86e-3)" "unprognostic (6.40e-2)" "unprognostic (8.17e-3)" "potential prognostic unfavorable (7.95e-4)" "unprognostic (3.53e-3)" "unprognostic (1.27e-1)" "unprognostic (2.22e-3)" "unprognostic (4.12e-3)" "unprognostic (4.58e-2)" "unprognostic (6.74e-2)" "unprognostic (2.06e-1)" "unprognostic (5.26e-2)" RNF10 "KIAA0262, RIE2" ENSG00000022840 "Ring finger protein 10" Q8N5U6 12 120533480-120577588 "Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 459.7;Neutrophils: 596.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052643 Approved Approved Nucleoplasm,Mitochondria No No "Cluster 42: Non-specific - Vesicular transport" "Cluster 52: Non-specific - Cellular respiration" "Cluster 7: Non-specific - Ribosome" "Cluster 38: Non-specific - Transcription" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 39 Nucleoplasm Mitochondria "HPA052643: " "unprognostic (5.65e-2)" "unprognostic (5.32e-2)" "unprognostic (2.47e-1)" "unprognostic (6.90e-3)" "unprognostic (1.27e-1)" "unprognostic (1.40e-2)" "unprognostic (2.20e-1)" "unprognostic (1.34e-1)" "unprognostic (2.14e-3)" "unprognostic (3.57e-2)" "unprognostic (6.99e-3)" "unprognostic (8.46e-3)" "unprognostic (8.33e-2)" "potential prognostic unfavorable (1.20e-4)" "unprognostic (1.01e-3)" "unprognostic (1.28e-3)" "unprognostic (2.04e-1)" "unprognostic (1.32e-1)" "unprognostic (2.68e-1)" "unprognostic (5.59e-1)" "unprognostic (3.31e-2)" "unprognostic (2.32e-1)" "unprognostic (3.82e-2)" "unprognostic (2.39e-1)" "unprognostic (2.60e-2)" "unprognostic (1.21e-1)" "unprognostic (6.48e-2)" "unprognostic (2.59e-1)" "unprognostic (9.94e-2)" "unprognostic (1.39e-1)" "unprognostic (1.14e-1)" RNF103 "hkf-1, KF1, ZFP103" ENSG00000239305 "Ring finger protein 103" O00237 2 86603398-86623866 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 34.5;Bergmann glia: 31.7;Brain excitatory neurons: 57.8;Brain inhibitory neurons: 44.6;Choroid plexus epithelial cells: 22.2;Ependymal cells: 21.6;Microglia: 25.1;Oligodendrocyte progenitor cells: 37.8;Oligodendrocytes: 55.6;Other brain neurons: 39.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 7.3" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057922 Approved NA NA "Cluster 41: Basophils - Unknown function" "Cluster 36: Brain & Liver - Signaling" "Cluster 25: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 2 "HPA057922: " "unprognostic (2.03e-3)" "unprognostic (8.45e-2)" "unprognostic (2.37e-1)" "unprognostic (1.20e-1)" "unprognostic (2.47e-1)" "unprognostic (2.07e-1)" "unprognostic (1.59e-1)" "unprognostic (1.65e-1)" "unprognostic (1.85e-1)" "unprognostic (3.13e-1)" "potential prognostic favorable (9.85e-6)" "unprognostic (1.13e-2)" "potential prognostic unfavorable (2.01e-4)" "unprognostic (2.13e-1)" "unprognostic (1.08e-1)" "unprognostic (1.84e-1)" "unprognostic (1.14e-1)" "unprognostic (3.05e-1)" "unprognostic (1.01e-1)" "unprognostic (1.44e-1)" "unprognostic (3.17e-2)" "unprognostic (1.35e-2)" "unprognostic (3.27e-1)" "unprognostic (3.62e-1)" "unprognostic (1.48e-1)" "unprognostic (2.30e-2)" "unprognostic (3.67e-1)" "unprognostic (2.76e-1)" "unprognostic (9.32e-2)" "unprognostic (2.92e-1)" "unprognostic (9.24e-2)" RNF103-CHMP3 RNF103-VPS24 ENSG00000249884 "RNF103-CHMP3 readthrough" 2 86505668-86721122 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 3.9;heart muscle: 3.9" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 56.6;Foveolar cells: 73.8;Goblet cells: 71.8;Neutrophils: 44.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "HPA015673, HPA073383" Uncertain NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 15: Non-specific - Transcription" "Cluster 6: Leukemia - Signal transduction" "Cluster 70: Intestinal goblet cells - Mucin production" "HPA015673: , HPA073383: " "unprognostic (2.14e-2)" "unprognostic (1.00e-3)" "unprognostic (3.80e-2)" "unprognostic (7.96e-2)" RNF11 "CGI-123, MGC51169, Sid1669p" ENSG00000123091 "Ring finger protein 11" Q9Y3C5 1 51236273-51273447 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 698.9;Neutrophils: 347.6;Platelets: 742.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 22.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045781 Uncertain NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 37: Non-specific - mRNA processing" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 200 "HPA045781: " "unprognostic (5.15e-2)" "unprognostic (1.62e-1)" "unprognostic (2.50e-1)" "unprognostic (1.15e-1)" "unprognostic (1.71e-2)" "unprognostic (1.32e-1)" "unprognostic (4.99e-3)" "unprognostic (1.05e-1)" "unprognostic (1.12e-1)" "unprognostic (7.06e-2)" "potential prognostic favorable (8.55e-9)" "unprognostic (5.67e-3)" "unprognostic (1.50e-1)" "unprognostic (3.92e-3)" "unprognostic (3.38e-1)" "unprognostic (2.57e-1)" "unprognostic (2.11e-1)" "unprognostic (7.46e-2)" "unprognostic (1.01e-1)" "unprognostic (5.28e-2)" "unprognostic (2.25e-3)" "unprognostic (4.71e-2)" "unprognostic (1.51e-1)" "unprognostic (1.52e-1)" "unprognostic (3.25e-2)" "unprognostic (9.75e-2)" "unprognostic (4.66e-2)" "unprognostic (9.29e-3)" "unprognostic (2.37e-1)" "unprognostic (1.35e-1)" "unprognostic (5.25e-2)" RNF111 "ARK, Arkadia, DKFZP761D081, FLJ38008" ENSG00000157450 "Ring finger protein 111" Q6ZNA4 15 58865175-59097419 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Developmental protein, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 637.7;Cardiomyocytes: 869.1;Epicardial cells: 664.0;Myonuclei: 488.4;Sertoli cells: 821.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038576, HPA038577" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 89: Adipocytes - Lipid metabolism" 50 Nucleoplasm Cytosol "HPA038576: , HPA038577: " "unprognostic (2.27e-2)" "unprognostic (1.73e-2)" "unprognostic (8.15e-2)" "unprognostic (7.55e-2)" "unprognostic (3.48e-1)" "unprognostic (1.82e-1)" "unprognostic (1.27e-1)" "unprognostic (2.05e-1)" "unprognostic (2.89e-1)" "unprognostic (1.49e-3)" "validated prognostic favorable (2.52e-6)" "validated prognostic favorable (5.63e-5)" "unprognostic (4.49e-1)" "unprognostic (2.29e-1)" "unprognostic (1.48e-1)" "unprognostic (2.35e-1)" "unprognostic (6.39e-2)" "unprognostic (1.08e-1)" "unprognostic (3.32e-2)" "unprognostic (2.41e-3)" "unprognostic (2.62e-2)" "unprognostic (3.83e-3)" "unprognostic (5.58e-3)" "unprognostic (3.58e-1)" "unprognostic (1.28e-1)" "unprognostic (1.39e-1)" "unprognostic (1.34e-2)" "unprognostic (2.00e-1)" "unprognostic (1.52e-1)" "unprognostic (2.65e-2)" "unprognostic (2.05e-2)" RNF112 "BFP, ZNF179" ENSG00000128482 "Ring finger protein 112" Q9ULX5 17 19411125-19417276 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Neurogenesis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 105.5" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 10.6;Astrocytes: 10.8;Brain excitatory neurons: 32.5;Brain inhibitory neurons: 25.8;Fibro-adipogenic progenitors: 11.1;Lactotrophs: 6.7;Müller glia: 11.0;Oligodendrocyte progenitor cells: 21.1;Oligodendrocytes: 6.1;Other brain neurons: 19.9" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in some" 9 "Glioblastoma Multiforme (TCGA): 13.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Neuroblastoma: 15.4" "Adrenal gland - Adrenal medulla cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA015970 Enhanced Approved "Nuclear speckles" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 15: Non-specific - Transcription" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" 21 "Nuclear speckles" "HPA015970: " "unprognostic (1.19e-2)" "unprognostic (2.13e-2)" "potential prognostic favorable (1.58e-5)" "unprognostic (2.74e-1)" "unprognostic (1.68e-1)" RNF113A "Cwc24, RNF113, ZNF183" ENSG00000125352 "Ring finger protein 113A" O15541 X 119870475-119871733 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, mRNA processing, mRNA splicing, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 50.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "HPA000160, HPA076658" Approved Supported Nucleoplasm NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 49: Non-specific - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 67: Plasma cells - Plasma cell differentiation" 24 Nucleoplasm "HPA000160: , HPA076658: " "unprognostic (2.98e-1)" "unprognostic (1.80e-1)" "unprognostic (6.64e-2)" "unprognostic (7.75e-2)" "unprognostic (2.19e-2)" "unprognostic (1.08e-1)" "unprognostic (1.34e-1)" "unprognostic (2.44e-2)" "unprognostic (2.66e-2)" "unprognostic (9.96e-3)" "unprognostic (1.49e-3)" "unprognostic (1.43e-1)" "unprognostic (1.17e-1)" "unprognostic (1.61e-3)" "unprognostic (5.44e-2)" "unprognostic (2.76e-2)" "unprognostic (8.17e-3)" "unprognostic (7.05e-2)" "unprognostic (1.27e-1)" "unprognostic (1.38e-1)" "unprognostic (2.42e-1)" "unprognostic (2.81e-2)" "unprognostic (9.07e-2)" "unprognostic (1.08e-1)" "unprognostic (1.79e-1)" "unprognostic (2.84e-1)" "unprognostic (3.09e-1)" "unprognostic (2.26e-1)" "unprognostic (1.25e-1)" "unprognostic (4.83e-2)" "unprognostic (4.67e-2)" RNF113B "RNF161, ZNF183L1" ENSG00000139797 "Ring finger protein 113B" Q8IZP6 13 98175785-98177269 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 173 "testis: 44.5" "Cell type enriched" "Detected in some" 7 "Late primary spermatocytes: 202.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Prostate - Prostate glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 51: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" "unprognostic (1.05e-1)" "unprognostic (1.37e-2)" RNF114 "PSORS12, ZNF313" ENSG00000124226 "Ring finger protein 114" Q9Y508 20 49936336-49953885 "Enzymes, Predicted intracellular proteins" "Differentiation, Spermatogenesis, Ubl conjugation pathway" "Developmental protein, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 153.8" "Group enriched" "Detected in many" 6 "Early spermatids: 1419.4;Late primary spermatocytes: 1601.8;Late spermatids: 1103.6;Oocytes: 635.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Spleen - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021184 Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 67: Testis - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 24 "Plasma membrane, Cytosol" "HPA021184: " "unprognostic (2.30e-1)" "unprognostic (1.93e-3)" "unprognostic (2.74e-1)" "unprognostic (3.50e-2)" "unprognostic (5.13e-2)" "unprognostic (3.55e-1)" "unprognostic (8.46e-2)" "unprognostic (2.52e-2)" "unprognostic (8.08e-2)" "unprognostic (1.03e-2)" "potential prognostic favorable (1.07e-6)" "unprognostic (1.25e-2)" "unprognostic (2.47e-1)" "unprognostic (5.62e-3)" "unprognostic (4.23e-2)" "unprognostic (2.12e-1)" "unprognostic (3.45e-1)" "unprognostic (2.15e-1)" "unprognostic (5.38e-2)" "unprognostic (1.43e-1)" "unprognostic (5.13e-2)" "unprognostic (4.98e-2)" "unprognostic (2.05e-1)" "unprognostic (3.98e-2)" "unprognostic (2.71e-3)" "unprognostic (4.56e-2)" "unprognostic (7.24e-3)" "unprognostic (1.47e-1)" "unprognostic (1.83e-1)" "unprognostic (7.71e-2)" "unprognostic (7.32e-3)" RNF115 "CL469780, ZNF364" ENSG00000265491 "Ring finger protein 115" Q9Y4L5 1 145738868-145824095 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Myonuclei: 579.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 6.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019130 Approved Approved Nucleoli,Mitochondria NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 15: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 76 "Nucleoli, Mitochondria" "HPA019130: " "unprognostic (2.16e-2)" "unprognostic (5.69e-2)" "unprognostic (1.49e-1)" "unprognostic (5.32e-2)" "unprognostic (2.01e-1)" "unprognostic (1.60e-1)" "unprognostic (5.28e-2)" "unprognostic (1.44e-1)" "unprognostic (1.49e-2)" "unprognostic (5.60e-3)" "unprognostic (8.02e-3)" "unprognostic (3.40e-1)" "potential prognostic unfavorable (4.27e-4)" "unprognostic (2.98e-1)" "unprognostic (2.48e-1)" "unprognostic (1.70e-1)" "unprognostic (2.71e-1)" "unprognostic (2.59e-1)" "unprognostic (2.54e-2)" "unprognostic (9.00e-2)" "unprognostic (8.99e-2)" "unprognostic (1.03e-2)" "unprognostic (3.60e-2)" "unprognostic (2.07e-2)" "unprognostic (4.40e-1)" "unprognostic (1.45e-1)" "unprognostic (3.17e-1)" "unprognostic (3.80e-2)" RNF121 FLJ11099 ENSG00000137522 "Ring finger protein 121" Q9H920 11 71929018-71997597 "Enzymes, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046041 Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 24: Non-specific - Unknown function" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" "Golgi apparatus" "Nucleoplasm, Vesicles" "HPA046041: " "unprognostic (1.33e-1)" "unprognostic (8.52e-2)" "unprognostic (2.44e-2)" "unprognostic (2.00e-2)" "unprognostic (2.17e-1)" "unprognostic (1.27e-1)" "unprognostic (3.05e-1)" "unprognostic (1.06e-2)" "unprognostic (9.01e-3)" "unprognostic (9.88e-2)" "potential prognostic favorable (7.16e-8)" "unprognostic (5.34e-3)" "unprognostic (2.73e-3)" "potential prognostic unfavorable (5.51e-4)" "unprognostic (1.68e-2)" "unprognostic (1.13e-3)" "unprognostic (1.69e-3)" "unprognostic (2.66e-1)" "unprognostic (8.34e-2)" "unprognostic (6.92e-2)" "unprognostic (1.67e-2)" "unprognostic (4.47e-2)" "potential prognostic unfavorable (9.19e-4)" "unprognostic (8.04e-2)" "unprognostic (2.11e-1)" "unprognostic (4.16e-1)" "unprognostic (1.26e-1)" "unprognostic (2.48e-1)" "unprognostic (1.11e-1)" "unprognostic (4.73e-2)" "unprognostic (4.34e-1)" RNF122 FLJ12526 ENSG00000133874 "Ring finger protein 122" Q9H9V4 8 33547754-33567128 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial luminal cells: 62.6;Innate lymphoid cells: 67.5;Myonuclei: 141.5;Ovarian stromal cells: 114.0;pDCs: 65.2;Plasma cells: 65.2;Smooth muscle cells: 109.9;Vascular endothelial cells: 82.8" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 21.7;leukocyte: 16.2;upper rhombic lip: 18.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Myeloma: 39.2" "Colon - Neutrophils, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003888 Uncertain NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 24: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 103: Non-specific - Basic cellular processes" 6 "HPA003888: " "unprognostic (3.19e-2)" "unprognostic (1.31e-2)" "unprognostic (3.47e-1)" "unprognostic (2.13e-1)" "unprognostic (4.13e-2)" "unprognostic (1.30e-1)" "unprognostic (6.64e-2)" "unprognostic (1.51e-2)" "unprognostic (2.46e-2)" "unprognostic (1.97e-1)" "unprognostic (3.70e-1)" "unprognostic (2.58e-2)" "unprognostic (2.39e-2)" "unprognostic (8.83e-3)" "unprognostic (8.98e-2)" "unprognostic (3.08e-1)" "unprognostic (1.38e-1)" "unprognostic (1.58e-1)" "unprognostic (4.80e-2)" "unprognostic (1.20e-1)" "unprognostic (9.35e-2)" "unprognostic (2.68e-2)" "unprognostic (2.51e-1)" "unprognostic (1.39e-3)" "unprognostic (1.39e-1)" "unprognostic (9.06e-3)" "unprognostic (2.67e-1)" "unprognostic (5.78e-2)" "unprognostic (1.79e-1)" "potential prognostic unfavorable (6.83e-4)" "unprognostic (1.31e-1)" RNF123 "FLJ12565, KPC1" ENSG00000164068 "Ring finger protein 123" Q5XPI4 3 49689538-49721529 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 149.4;tongue: 104.4" "Cell type enhanced" "Detected in many" "Epicardial cells: 54.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065983, HPA071879" Enhanced Approved Cytosol NA NA 120000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 20 Cytosol "HPA065983: , HPA071879: " "unprognostic (8.51e-2)" "unprognostic (2.36e-1)" "unprognostic (2.80e-1)" "unprognostic (2.54e-1)" "unprognostic (1.28e-1)" "unprognostic (3.10e-1)" "unprognostic (2.78e-1)" "unprognostic (6.40e-2)" "unprognostic (1.38e-1)" "unprognostic (5.30e-2)" "unprognostic (5.17e-3)" "unprognostic (3.41e-1)" "potential prognostic favorable (1.25e-4)" "unprognostic (9.68e-3)" "unprognostic (6.73e-2)" "unprognostic (4.69e-2)" "unprognostic (2.00e-1)" "unprognostic (1.31e-1)" "unprognostic (4.16e-2)" "unprognostic (2.32e-1)" "unprognostic (1.01e-1)" "unprognostic (4.43e-2)" "unprognostic (8.66e-2)" "unprognostic (1.53e-2)" "unprognostic (3.44e-1)" "unprognostic (2.19e-2)" "unprognostic (2.62e-1)" "unprognostic (3.17e-1)" "unprognostic (3.16e-1)" "unprognostic (3.04e-1)" "unprognostic (3.51e-1)" RNF125 FLJ20456 ENSG00000101695 "Ring finger protein 125" Q96EQ8 18 32018825-32073219 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Adaptive immunity, Immunity, Ubl conjugation pathway" Transferase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.3" "Cell type enhanced" "Detected in some" "Early spermatids: 120.9;Innate lymphoid cells: 16.7;Late spermatids: 16.6;Microglia: 87.6;NK-cells: 46.6;Oligodendrocytes: 70.9;Papillary tip epithelial cells: 18.8;Proximal tubule cells: 25.5;Renal collecting duct principal cells: 25.6;T-cells: 23.4" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 110.5;leukocyte: 177.7;oligodendrocyte: 89.3" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 19.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "skin cancer: 9.6" "Spleen - NK-cells (Spleen), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041514 Uncertain Supported "Nucleoli,Golgi apparatus" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 49: HMC-1 - Innate immune response" "Cluster 102: Non-specific - Mixed function" 25 "Golgi apparatus" Nucleoli "HPA041514: " "unprognostic (3.75e-3)" "unprognostic (2.10e-1)" "potential prognostic favorable (4.57e-4)" "unprognostic (1.88e-1)" "unprognostic (3.74e-1)" "unprognostic (2.52e-1)" "unprognostic (2.25e-1)" "unprognostic (1.96e-1)" "unprognostic (2.09e-2)" "unprognostic (2.70e-1)" "potential prognostic favorable (3.24e-4)" "unprognostic (4.50e-3)" "unprognostic (1.27e-1)" "unprognostic (2.66e-3)" "potential prognostic favorable (5.78e-4)" "unprognostic (4.40e-2)" "unprognostic (4.55e-2)" "unprognostic (4.29e-1)" "unprognostic (3.42e-2)" "unprognostic (1.03e-1)" "unprognostic (2.20e-1)" "unprognostic (2.95e-1)" "unprognostic (5.58e-2)" "unprognostic (3.82e-1)" "unprognostic (6.41e-2)" "unprognostic (4.19e-2)" "unprognostic (1.66e-1)" "unprognostic (2.46e-1)" "unprognostic (4.00e-1)" "unprognostic (3.94e-2)" "unprognostic (1.83e-1)" RNF126 FLJ20552 ENSG00000070423 "Ring finger protein 126" Q9BV68 19 647526-663233 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 143.8;Esophageal apical cells: 167.3;Esophageal basal cells: 175.9;Esophageal suprabasal cells: 164.9;Extravillous trophoblasts: 174.0;Late primary spermatocytes: 284.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043050 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 24: Non-specific - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 23: Non-specific - Transcription" "Cluster 26: Keratinocytes - Keratinization" 38 Nucleoplasm Cytosol "HPA043050: " "unprognostic (3.19e-1)" "unprognostic (1.25e-1)" "unprognostic (7.23e-2)" "unprognostic (9.22e-2)" "unprognostic (9.71e-2)" "unprognostic (2.59e-2)" "unprognostic (2.35e-1)" "unprognostic (4.14e-2)" "unprognostic (8.33e-2)" "unprognostic (3.91e-2)" "potential prognostic favorable (1.94e-4)" "unprognostic (2.89e-1)" "unprognostic (2.15e-1)" "unprognostic (2.67e-3)" "unprognostic (5.45e-3)" "unprognostic (3.61e-3)" "unprognostic (2.00e-2)" "unprognostic (3.62e-1)" "unprognostic (1.84e-1)" "unprognostic (9.12e-3)" "unprognostic (5.01e-2)" "unprognostic (2.35e-2)" "unprognostic (2.06e-1)" "unprognostic (3.24e-3)" "unprognostic (2.22e-1)" "unprognostic (1.49e-2)" "unprognostic (1.66e-1)" "unprognostic (1.82e-2)" "unprognostic (1.17e-1)" "unprognostic (3.34e-1)" "unprognostic (7.66e-2)" RNF128 "FLJ23516, GRAIL" ENSG00000133135 "Ring finger protein 128" Q8TEB7 X 106693794-106797016 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 58.4;liver: 116.5" "Cell type enhanced" "Detected in many" "Enterocytes: 91.9;Foveolar cells: 208.4;Gonadotrophs: 112.7;Hepatocytes: 89.1;Parietal cells: 116.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Colon - Colon enterocytes, Liver - Hepatocytes, Pituitary gland - Gonadotropes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019675 Uncertain NA NA "Cluster 77: Intestine - Digestion" "Cluster 1: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 68: Foveolar cells - Mucosal defense" 9 "HPA019675: " "unprognostic (7.89e-3)" "unprognostic (6.66e-2)" "unprognostic (1.85e-1)" "unprognostic (8.22e-2)" "unprognostic (5.40e-2)" "unprognostic (1.34e-2)" "potential prognostic unfavorable (4.41e-4)" "unprognostic (3.36e-2)" "unprognostic (8.32e-3)" "unprognostic (4.09e-2)" "potential prognostic favorable (9.83e-5)" "unprognostic (1.28e-1)" "unprognostic (1.07e-3)" "unprognostic (3.70e-2)" "unprognostic (1.04e-1)" "unprognostic (7.98e-2)" "unprognostic (9.11e-2)" "unprognostic (1.97e-1)" "unprognostic (5.01e-3)" "unprognostic (8.12e-3)" "unprognostic (1.48e-1)" "unprognostic (2.92e-3)" "unprognostic (3.80e-1)" "unprognostic (1.53e-3)" "unprognostic (2.89e-1)" "potential prognostic favorable (6.39e-4)" "unprognostic (2.52e-1)" "unprognostic (3.34e-1)" "unprognostic (1.43e-2)" RNF13 RZF ENSG00000082996 "Ring finger protein 13" O43567 3 149812770-149962139 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 1686.1;Oligodendrocytes: 598.4" "Cell type enhanced" "Detected in all" "oligodendrocyte: 835.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 464.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064784 Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 63: Non-specific - Protein processing" "Cluster 24: Neutrophils - Innate immunity signal integration" 24 "Nucleoplasm, Vesicles" Cytosol "HPA064784: " "unprognostic (1.06e-1)" "unprognostic (2.50e-2)" "unprognostic (6.72e-2)" "unprognostic (1.13e-1)" "unprognostic (1.38e-1)" "unprognostic (8.30e-2)" "unprognostic (4.70e-2)" "unprognostic (3.30e-2)" "unprognostic (2.20e-1)" "unprognostic (1.80e-3)" "potential prognostic favorable (8.08e-13)" "unprognostic (4.45e-3)" "unprognostic (1.25e-1)" "unprognostic (2.73e-2)" "unprognostic (4.25e-1)" "unprognostic (2.67e-1)" "unprognostic (5.34e-2)" "unprognostic (1.79e-2)" "unprognostic (6.52e-2)" "unprognostic (1.24e-1)" "unprognostic (5.91e-3)" "unprognostic (1.12e-3)" "unprognostic (2.76e-2)" "unprognostic (3.45e-1)" "unprognostic (9.66e-2)" "unprognostic (3.61e-2)" "unprognostic (2.20e-1)" "unprognostic (1.72e-1)" "unprognostic (2.42e-1)" "unprognostic (3.09e-1)" "unprognostic (2.56e-1)" RNF130 "G1RZFP, GOLIATH, GP" ENSG00000113269 "Ring finger protein 130" Q86XS8 5 179911651-180072113 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Mast cells: 864.3;Megakaryocyte progenitors: 1108.7;Megakaryocyte-Erythroid progenitors: 1592.7;Neutrophils: 1382.5;Oligodendrocytes: 719.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 8 "basophil: 262.7;classical monocyte: 513.7;eosinophil: 331.9;intermediate monocyte: 355.0;myeloid DC: 407.7;neutrophil: 893.5;non-classical monocyte: 330.1;plasmacytoid DC: 317.6" "Group enriched" "Detected in all" 11 "dendritic cells: 407.7;granulocytes: 893.5;monocytes: 513.7" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014499 Approved NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 49: HMC-1 - Innate immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 9 "HPA014499: " "unprognostic (8.82e-2)" "unprognostic (1.45e-1)" "unprognostic (1.09e-1)" "unprognostic (8.03e-3)" "unprognostic (3.24e-1)" "unprognostic (8.17e-3)" "unprognostic (2.33e-2)" "unprognostic (1.21e-1)" "unprognostic (6.23e-2)" "unprognostic (4.98e-2)" "potential prognostic favorable (1.01e-7)" "unprognostic (1.84e-2)" "unprognostic (4.82e-2)" "unprognostic (6.29e-2)" "unprognostic (2.41e-2)" "unprognostic (5.37e-3)" "unprognostic (1.93e-2)" "unprognostic (3.55e-1)" "unprognostic (1.79e-1)" "unprognostic (2.92e-2)" "potential prognostic unfavorable (4.18e-4)" "unprognostic (1.50e-1)" "unprognostic (9.44e-2)" "unprognostic (2.47e-1)" "unprognostic (6.07e-2)" "unprognostic (1.13e-1)" "unprognostic (4.05e-2)" "unprognostic (6.71e-3)" "unprognostic (2.02e-1)" "unprognostic (1.26e-1)" "unprognostic (3.26e-3)" RNF133 ENSG00000188050 "Ring finger protein 133" Q8WVZ7 7 122697735-122699117 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 68 "testis: 41.4" "Group enriched" "Detected in some" 10 "Early spermatids: 39.8;Late spermatids: 98.5" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebellum: 15.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 2: Neurons - Nucleosome" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 4 "unprognostic (5.77e-3)" "unprognostic (2.78e-1)" "unprognostic (4.58e-2)" RNF135 MGC13061 ENSG00000181481 "Ring finger protein 135" Q8IUD6 17 30970984-30999911 "Enzymes, Human disease related genes, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 63.1;Esophageal apical cells: 68.5;Hofbauer cells: 83.8;Kupffer cells: 150.7;Macrophages: 63.9;Neutrophils: 76.7" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 63.8;pericyte: 44.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021576, HPA052404" Approved Approved Vesicles NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 58: Skin - Keratinization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 27: Breast cancer - Unknown function" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 11 Vesicles "HPA021576: , HPA052404: " "unprognostic (1.04e-1)" "unprognostic (1.77e-2)" "unprognostic (4.39e-2)" "unprognostic (1.21e-1)" "unprognostic (1.22e-1)" "unprognostic (4.65e-2)" "unprognostic (1.14e-2)" "unprognostic (1.79e-2)" "unprognostic (4.16e-2)" "unprognostic (1.11e-2)" "unprognostic (7.14e-2)" "unprognostic (6.79e-2)" "unprognostic (8.48e-2)" "unprognostic (1.26e-1)" "unprognostic (1.12e-2)" "unprognostic (6.32e-2)" "unprognostic (8.54e-2)" "unprognostic (5.87e-2)" "unprognostic (7.14e-2)" "unprognostic (2.36e-1)" "unprognostic (2.68e-1)" "unprognostic (2.56e-2)" "unprognostic (3.38e-1)" "unprognostic (3.39e-2)" "unprognostic (3.10e-1)" "unprognostic (4.60e-2)" "unprognostic (1.83e-2)" "unprognostic (2.32e-2)" "unprognostic (1.65e-1)" "unprognostic (8.97e-3)" "unprognostic (2.97e-1)" RNF138 "NARF, STRIN" ENSG00000134758 "Ring finger protein 138" Q8WVD3 18 32091874-32131561 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway, Wnt signaling pathway" "DNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 90.6;testis: 113.0" "Cell type enriched" "Detected in many" 6 "Late spermatids: 7000.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041101 Approved Mitochondria NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 13: Non-specific - Mixed function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 25 Mitochondria "HPA041101: " "unprognostic (3.66e-2)" "unprognostic (1.63e-1)" "unprognostic (9.06e-2)" "unprognostic (1.36e-1)" "unprognostic (2.69e-3)" "unprognostic (8.50e-2)" "unprognostic (8.94e-2)" "unprognostic (9.66e-2)" "unprognostic (3.60e-2)" "unprognostic (7.45e-3)" "potential prognostic favorable (7.01e-4)" "unprognostic (5.84e-3)" "unprognostic (1.37e-1)" "unprognostic (4.47e-3)" "unprognostic (2.07e-3)" "unprognostic (1.22e-1)" "unprognostic (7.74e-2)" "unprognostic (1.40e-1)" "unprognostic (2.42e-3)" "unprognostic (2.66e-2)" "unprognostic (3.41e-1)" "unprognostic (2.61e-1)" "unprognostic (4.63e-2)" "unprognostic (1.46e-2)" "unprognostic (3.34e-2)" "unprognostic (1.19e-1)" "unprognostic (5.92e-2)" "unprognostic (1.93e-1)" "unprognostic (3.25e-1)" "unprognostic (1.45e-1)" "unprognostic (6.76e-2)" RNF139 "HRCA1, RCA1, TRC8" ENSG00000170881 "Ring finger protein 139" Q8WU17 8 124474880-124488618 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Receptor, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 88.0" "Group enriched" "Detected in many" 4 "Early spermatids: 964.6;Late spermatids: 1594.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001202 Approved NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 6 "HPA001202: " "unprognostic (2.79e-1)" "potential prognostic unfavorable (8.12e-4)" "unprognostic (5.70e-2)" "unprognostic (2.07e-3)" "unprognostic (2.68e-2)" "unprognostic (4.80e-3)" "unprognostic (2.45e-2)" "unprognostic (6.80e-2)" "unprognostic (7.81e-2)" "unprognostic (1.43e-1)" "potential prognostic favorable (4.44e-5)" "unprognostic (1.00e-3)" "unprognostic (8.06e-2)" "unprognostic (2.11e-2)" "unprognostic (2.73e-2)" "unprognostic (3.27e-2)" "unprognostic (4.43e-2)" "unprognostic (1.61e-1)" "unprognostic (2.96e-2)" "unprognostic (6.05e-2)" "unprognostic (7.93e-3)" "unprognostic (1.35e-3)" "unprognostic (5.78e-2)" "unprognostic (4.19e-2)" "unprognostic (9.54e-2)" "unprognostic (5.78e-2)" "unprognostic (2.31e-1)" "unprognostic (1.26e-1)" "unprognostic (3.31e-1)" "unprognostic (1.81e-1)" "unprognostic (9.57e-2)" RNF14 "ARA54, HFB30, TRIAD2" ENSG00000013561 "Ring finger protein 14" Q9UBS8 5 141958328-141990292 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 308.3;Late primary spermatocytes: 195.5;Parietal cells: 116.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008716, HPA064746" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 61: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 19 Nucleoplasm Cytosol "HPA008716: , HPA064746: " "unprognostic (1.44e-2)" "unprognostic (2.11e-2)" "unprognostic (2.15e-2)" "unprognostic (1.12e-1)" "unprognostic (7.96e-2)" "unprognostic (1.35e-3)" "unprognostic (8.36e-2)" "potential prognostic unfavorable (1.23e-4)" "unprognostic (2.39e-2)" "unprognostic (8.53e-3)" "potential prognostic favorable (1.73e-10)" "unprognostic (2.26e-3)" "unprognostic (2.13e-1)" "unprognostic (3.95e-1)" "unprognostic (2.69e-2)" "unprognostic (9.34e-2)" "unprognostic (4.69e-1)" "unprognostic (3.15e-2)" "unprognostic (4.46e-2)" "unprognostic (1.69e-1)" "unprognostic (2.19e-2)" "unprognostic (1.97e-1)" "unprognostic (6.86e-2)" "unprognostic (2.11e-1)" "unprognostic (7.09e-2)" "unprognostic (5.41e-2)" "unprognostic (2.02e-1)" "unprognostic (1.34e-2)" "unprognostic (1.59e-1)" "unprognostic (1.04e-2)" "unprognostic (1.12e-1)" RNF141 "ZFP26, ZNF230" ENSG00000110315 "Ring finger protein 141" Q8WVD5 11 10511673-10541230 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 1167.9;Esophageal apical cells: 695.9;Late primary spermatocytes: 326.7;Late spermatids: 838.9" "Cell type enhanced" "Detected in all" "oligodendrocyte: 98.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Adrenal cortex cells, Skin - Keratinocyte (other), Spleen - Macrophages, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018133 Approved Approved Nucleoplasm,Microtubules NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 7 Microtubules Nucleoplasm "HPA018133: " "unprognostic (1.20e-1)" "unprognostic (6.40e-2)" "unprognostic (3.10e-1)" "unprognostic (3.89e-2)" "unprognostic (1.92e-2)" "unprognostic (1.41e-1)" "unprognostic (6.24e-2)" "unprognostic (2.15e-3)" "unprognostic (1.01e-1)" "unprognostic (1.57e-2)" "potential prognostic favorable (4.59e-6)" "unprognostic (2.14e-2)" "unprognostic (8.35e-2)" "potential prognostic unfavorable (1.65e-4)" "unprognostic (1.55e-1)" "unprognostic (2.84e-2)" "unprognostic (7.78e-2)" "unprognostic (6.95e-2)" "unprognostic (6.89e-2)" "unprognostic (4.44e-1)" "potential prognostic unfavorable (6.65e-5)" "potential prognostic unfavorable (3.11e-5)" "unprognostic (6.58e-2)" "unprognostic (1.27e-1)" "unprognostic (1.93e-3)" "unprognostic (5.94e-2)" "unprognostic (5.62e-2)" "unprognostic (1.25e-1)" "unprognostic (9.71e-2)" "unprognostic (2.32e-3)" "unprognostic (2.64e-2)" RNF144A "hUIP4, KIAA0161, RNF144, UBCE7IP4" ENSG00000151692 "Ring finger protein 144A" P50876 2 6917412-7068286 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 54.5" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 307.9;Cone photoreceptor cells: 681.1;Gonadotrophs: 358.4;Oligodendrocyte progenitor cells: 354.6;Oligodendrocytes: 493.7;Rod photoreceptor cells: 489.6;Somatotrophs: 245.8;Thyrotrophs: 232.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 6.1" "Group enriched" "Detected in many" 8 "granulocytes: 6.1;T-cells: 2.4" "Cancer enhanced" "Detected in many" "Neuroblastoma: 27.7;skin cancer: 30.3" "Adrenal gland - Adrenal cortex cells, Colon - Enteric glia cells, Prostate - Fibroblasts, Spleen - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049939 Approved Supported Vesicles NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 27: Cerebellum - Synaptic function" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 79: Photoreceptor cells - Phototransduction" 26 Vesicles "HPA049939: " "unprognostic (1.33e-2)" "unprognostic (4.02e-1)" "unprognostic (6.37e-2)" "unprognostic (6.81e-2)" "unprognostic (2.04e-1)" "unprognostic (1.88e-1)" "unprognostic (4.22e-2)" "unprognostic (4.64e-3)" "unprognostic (6.34e-3)" "potential prognostic unfavorable (2.87e-5)" "unprognostic (9.85e-3)" "unprognostic (1.05e-2)" "unprognostic (1.18e-3)" "potential prognostic unfavorable (1.73e-4)" "unprognostic (9.77e-3)" "unprognostic (4.94e-2)" "unprognostic (3.71e-2)" "unprognostic (5.92e-2)" "unprognostic (2.50e-1)" "unprognostic (9.94e-2)" "unprognostic (7.49e-2)" "unprognostic (4.95e-2)" "unprognostic (6.77e-2)" "unprognostic (1.90e-1)" "unprognostic (9.24e-3)" "unprognostic (1.97e-2)" "unprognostic (1.47e-2)" "potential prognostic unfavorable (4.20e-6)" "unprognostic (7.18e-2)" "unprognostic (6.99e-2)" "unprognostic (7.40e-2)" RNF144B "bA528A10.3, IBRDC2, P53RFP" ENSG00000137393 "Ring finger protein 144B" Q7Z419 6 18387350-18468870 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 53.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 705.4;cDC: 613.5;Epididymal basal cells: 498.1;Kupffer cells: 442.8;Macrophages: 522.3;monocytes: 1203.4;Neutrophil progenitors: 507.8;Neutrophils: 3933.9;Suprabasal keratinocytes: 1427.4" "Cell type enriched" "Detected in many" 5 "endothelial cell: 655.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 72.3" "Group enriched" "Detected in many" 9 "dendritic cells: 18.4;granulocytes: 36.8;monocytes: 72.3" "Cancer enhanced" "Detected in many" "lymphoma: 28.9" "Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046013, HPA054127, HPA072469" Uncertain Approved Nucleoli,Mitochondria NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 47: Endothelial cells - Vasculature" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 10 Nucleoli Mitochondria "CAB046013: , HPA054127: , HPA072469: " "unprognostic (1.29e-1)" "unprognostic (9.36e-3)" "unprognostic (1.71e-1)" "unprognostic (2.24e-1)" "unprognostic (3.38e-1)" "unprognostic (3.75e-2)" "unprognostic (6.26e-2)" "unprognostic (2.95e-1)" "unprognostic (6.43e-3)" "unprognostic (9.91e-2)" "potential prognostic favorable (2.33e-4)" "unprognostic (3.49e-2)" "unprognostic (1.42e-1)" "unprognostic (3.17e-1)" "potential prognostic favorable (4.09e-5)" "unprognostic (1.90e-2)" "unprognostic (1.23e-1)" "unprognostic (2.71e-1)" "unprognostic (5.53e-1)" "unprognostic (1.89e-2)" "unprognostic (1.14e-1)" "unprognostic (3.21e-2)" "unprognostic (1.72e-2)" "unprognostic (1.83e-1)" "unprognostic (6.93e-2)" "unprognostic (6.85e-2)" "unprognostic (4.73e-2)" "unprognostic (8.17e-2)" "unprognostic (1.48e-1)" "unprognostic (7.23e-2)" "unprognostic (7.82e-3)" RNF145 FLJ31951 ENSG00000145860 "Ring finger protein 145" Q96MT1 5 159157409-159210053 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 664.5;Transitional alveolar cells: 607.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "B-cells: 11.4;granulocytes: 16.0;T-cells: 6.3" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Liver - Vascular endothelial cells, Lung - Alveolar cells type 2, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036562 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 1 "Nucleoplasm, Plasma membrane, Cytosol" "HPA036562: " "unprognostic (1.97e-1)" "unprognostic (2.00e-1)" "unprognostic (1.78e-2)" "unprognostic (4.71e-2)" "unprognostic (1.34e-2)" "unprognostic (1.50e-1)" "unprognostic (1.22e-1)" "unprognostic (1.44e-3)" "unprognostic (1.90e-2)" "unprognostic (4.61e-2)" "potential prognostic favorable (6.03e-7)" "unprognostic (6.11e-2)" "unprognostic (1.34e-2)" "potential prognostic unfavorable (3.92e-5)" "unprognostic (4.33e-2)" "unprognostic (8.18e-2)" "unprognostic (1.81e-2)" "unprognostic (1.32e-1)" "unprognostic (3.81e-1)" "unprognostic (2.12e-1)" "unprognostic (2.91e-3)" "unprognostic (7.68e-2)" "unprognostic (3.51e-1)" "unprognostic (4.04e-2)" "unprognostic (4.24e-2)" "unprognostic (1.98e-2)" "unprognostic (1.74e-2)" "unprognostic (2.66e-3)" "unprognostic (4.11e-1)" "unprognostic (1.24e-1)" "unprognostic (2.41e-1)" RNF146 "dactylidin, dJ351K20.1, DKFZp434O1427" ENSG00000118518 "Ring finger protein 146" Q9NTX7 6 127266726-127288567 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway, Wnt signaling pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Myonuclei: 168.4;Neutrophils: 173.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027158, HPA027209" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" No No "Cluster 35: Neutrophils - Protein binding" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 25: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 24: Neutrophils - Innate immunity signal integration" 41 "Plasma membrane, Cytosol" Nucleoplasm "HPA027158: , HPA027209: " "unprognostic (1.10e-1)" "unprognostic (4.18e-3)" "unprognostic (3.44e-2)" "unprognostic (7.48e-3)" "unprognostic (5.52e-2)" "unprognostic (7.11e-2)" "unprognostic (5.67e-2)" "unprognostic (8.36e-2)" "unprognostic (2.68e-2)" "unprognostic (4.38e-2)" "potential prognostic favorable (1.26e-6)" "unprognostic (7.72e-3)" "unprognostic (2.07e-1)" "unprognostic (5.89e-3)" "unprognostic (9.05e-2)" "unprognostic (2.32e-2)" "unprognostic (3.71e-1)" "unprognostic (9.35e-2)" "unprognostic (2.48e-1)" "unprognostic (2.00e-2)" "unprognostic (4.47e-2)" "unprognostic (1.89e-3)" "unprognostic (1.06e-1)" "unprognostic (1.84e-1)" "unprognostic (1.16e-1)" "unprognostic (2.02e-2)" "unprognostic (1.52e-1)" "unprognostic (2.25e-2)" "unprognostic (7.60e-2)" "unprognostic (2.19e-2)" "unprognostic (3.02e-1)" RNF148 MGC35222 ENSG00000235631 "Ring finger protein 148" Q8N7C7 7 122701668-122702922 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 86 "testis: 48.3" "Cell type enhanced" "Detected in some" "Early spermatids: 8.7;Late primary spermatocytes: 3.9;Late spermatids: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in all" "cerebellum: 22.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" HPA045587 Approved Cytosol NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 2: Neurons - Nucleosome" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" Cytosol "HPA045587: " "unprognostic (2.61e-1)" "unprognostic (1.52e-1)" "unprognostic (4.46e-1)" "unprognostic (1.30e-1)" RNF149 FLJ90504 ENSG00000163162 "Ring finger protein 149" Q8NC42 2 101271219-101308701 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 5 "Neutrophils: 6808.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "neutrophil: 621.0" "Lineage enriched" "Detected in all" 5 "granulocytes: 621.0" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011424 Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 24: Neutrophils - Innate immunity signal integration" 50 "Vesicles, Plasma membrane" "HPA011424: " "unprognostic (3.87e-1)" "unprognostic (1.43e-2)" "unprognostic (4.98e-2)" "unprognostic (2.04e-2)" "unprognostic (1.78e-1)" "unprognostic (9.42e-2)" "unprognostic (5.19e-2)" "unprognostic (2.26e-1)" "unprognostic (1.41e-3)" "unprognostic (2.33e-1)" "unprognostic (6.01e-2)" "unprognostic (2.22e-1)" "unprognostic (1.02e-3)" "unprognostic (4.76e-3)" "unprognostic (2.68e-3)" "unprognostic (4.52e-3)" "unprognostic (7.43e-3)" "unprognostic (3.73e-2)" "unprognostic (2.48e-1)" "unprognostic (8.25e-2)" "unprognostic (6.35e-2)" "unprognostic (1.37e-3)" "potential prognostic unfavorable (4.14e-4)" "unprognostic (2.51e-1)" "unprognostic (3.68e-1)" "unprognostic (1.06e-1)" "unprognostic (1.49e-1)" "unprognostic (5.24e-2)" "unprognostic (1.54e-1)" "unprognostic (9.10e-2)" "unprognostic (5.30e-2)" RNF150 KIAA1214 ENSG00000170153 "Ring finger protein 150" Q9ULK6 4 140859807-141212877 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 597.5;Adrenal cortex cells: 496.5;Cardiomyocytes: 671.9;Cone photoreceptor cells: 571.4;Corticotrophs: 574.1;Lactotrophs: 1281.5;Retinal pigment epithelial cells: 673.5;Rod photoreceptor cells: 461.0;Salivary acinar cells: 640.6;Somatotrophs: 550.7;Thyrotrophs: 723.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Neuroblastoma: 26.3" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Adrenal cortex cells, Liver - Hepatic stellate cells, Pituitary gland - Lactotropes, Stomach - Fibroblasts, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037987 Uncertain "Intracellular and membrane" "No annotated function" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 33: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" "HPA037987: " "unprognostic (1.49e-2)" "potential prognostic favorable (6.71e-4)" "unprognostic (1.01e-1)" "unprognostic (9.76e-2)" "unprognostic (8.24e-2)" "unprognostic (1.06e-1)" "unprognostic (8.92e-3)" "unprognostic (8.25e-2)" "potential prognostic unfavorable (2.11e-4)" "unprognostic (2.51e-3)" "unprognostic (4.89e-3)" "unprognostic (1.40e-1)" "unprognostic (1.80e-1)" "unprognostic (1.58e-3)" "unprognostic (8.46e-2)" "unprognostic (4.14e-3)" "unprognostic (5.91e-2)" "unprognostic (7.38e-2)" "unprognostic (1.03e-2)" "unprognostic (3.03e-1)" "unprognostic (2.56e-1)" "unprognostic (3.92e-3)" "unprognostic (8.44e-2)" "unprognostic (6.09e-3)" "unprognostic (1.44e-1)" "unprognostic (2.19e-3)" "unprognostic (6.09e-2)" RNF151 ENSG00000179580 "Ring finger protein 151" Q2KHN1 16 1966823-1968975 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 940 "testis: 186.0" "Group enriched" "Detected in some" 6 "Early spermatids: 2667.3;Late spermatids: 1977.0" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA055054 Approved "Nuclear speckles,Vesicles,Cytosol" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 6: Non-specific - Immune response" "Cluster 70: DU4475 - Unknown function" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 61 Cytosol "Nuclear speckles, Vesicles" "HPA055054: " RNF152 FLJ39176 ENSG00000176641 "Ring finger protein 152" Q8N8N0 18 61808067-61894247 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 52.8" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 654.2;Lacrimal acinar cells: 366.9;Pericytes: 365.0;Proximal tubule cells: 1090.7;Renal collecting duct intercalated cells: 1618.0;Salivary ionocytes: 523.3;Vascular smooth muscle cells: 303.7" "Group enriched" "Detected in all" 4 "choroid plexus epithelial cell: 534.1;pericyte: 830.7;vascular associated smooth muscle cell: 811.3" "Cancer enriched" "Detected in all" 4 "Kidney Chromophobe (TCGA): 68.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Minor Salivary Gland - Minor salivary gland ductal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 76: Non-specific - Metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 13 "unprognostic (1.20e-1)" "unprognostic (2.89e-2)" "unprognostic (1.85e-1)" "unprognostic (1.65e-1)" "unprognostic (2.67e-1)" "unprognostic (3.87e-1)" "unprognostic (9.02e-2)" "potential prognostic favorable (1.66e-6)" "unprognostic (2.07e-1)" "unprognostic (1.98e-2)" "validated prognostic favorable (3.43e-8)" "validated prognostic favorable (8.94e-6)" "unprognostic (1.64e-2)" "unprognostic (1.53e-2)" "unprognostic (1.81e-1)" "unprognostic (7.57e-2)" "unprognostic (2.62e-1)" "unprognostic (1.53e-1)" "unprognostic (1.11e-2)" "unprognostic (4.70e-2)" "unprognostic (1.01e-2)" "unprognostic (6.96e-3)" "unprognostic (2.95e-1)" "unprognostic (2.04e-1)" "unprognostic (1.96e-1)" "unprognostic (1.66e-1)" "potential prognostic unfavorable (8.31e-4)" "unprognostic (6.36e-3)" "unprognostic (1.46e-1)" "unprognostic (1.59e-2)" "unprognostic (5.15e-2)" RNF157 KIAA1917 ENSG00000141576 "Ring finger protein 157" Q96PX1 17 76142465-76240493 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 73.6;retina: 54.7;skeletal muscle: 69.2" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 93.1;Cone photoreceptor cells: 236.0;Oligodendrocyte progenitor cells: 92.0;Retinal amacrine cells: 131.0;Retinal bipolar cells: 175.7;Retinal ganglion cells: 189.3;Retinal horizontal cells: 306.5;Rod photoreceptor cells: 102.2;Sertoli cells: 97.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 33.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "granulocytes: 2.1;T-cells: 5.8" "Cancer enhanced" "Detected in many" "Neuroblastoma: 49.4" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Spleen - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021854, HPA021991, HPA023922" Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 6 "Golgi apparatus" Vesicles "HPA021854: , HPA021991: , HPA023922: " "unprognostic (7.88e-2)" "unprognostic (3.29e-1)" "unprognostic (5.03e-2)" "unprognostic (1.20e-1)" "unprognostic (1.35e-3)" "unprognostic (2.36e-1)" "unprognostic (1.83e-1)" "unprognostic (1.31e-1)" "unprognostic (7.76e-2)" "unprognostic (1.46e-1)" "unprognostic (2.71e-1)" "unprognostic (3.03e-1)" "unprognostic (4.90e-2)" "unprognostic (1.31e-3)" "unprognostic (6.06e-3)" "unprognostic (3.22e-2)" "unprognostic (2.76e-1)" "unprognostic (2.40e-1)" "unprognostic (4.17e-2)" "unprognostic (1.76e-2)" "unprognostic (4.47e-2)" "unprognostic (3.55e-3)" "unprognostic (1.99e-1)" "unprognostic (1.09e-1)" "unprognostic (1.15e-1)" "unprognostic (1.52e-1)" "unprognostic (3.45e-2)" "unprognostic (6.86e-3)" "unprognostic (2.37e-1)" "unprognostic (4.59e-2)" "unprognostic (5.18e-2)" RNF165 "Ark2C, ARKL2, lncAMPC, RNF111L2" ENSG00000141622 "Ring finger protein 165" Q6ZSG1 18 46326809-46463140 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 21.7;retina: 16.9" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 78.8;Brain inhibitory neurons: 66.4;Cone photoreceptor cells: 93.2;Ependymal cells: 75.5;Epididymal basal cells: 60.5;Epididymal efferent duct ciliated cells: 73.0;Lactotrophs: 84.0;NK-cells: 63.6;Oligodendrocyte progenitor cells: 57.7;Other brain neurons: 56.9;Pituitary stem cells: 70.2;Retinal amacrine cells: 177.8;Retinal horizontal cells: 122.2;Thyrotrophs: 66.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 1.1" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in many" 5 "Neuroblastoma: 12.7" "Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Pituitary gland - Lactotropes, Prostate - Prostate basal glandular cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041615, HPA047798" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 4 "Nucleoplasm, Plasma membrane" "HPA041615: , HPA047798: " "unprognostic (7.83e-2)" "unprognostic (3.24e-2)" "unprognostic (4.16e-1)" "unprognostic (2.76e-2)" "unprognostic (1.75e-1)" "potential prognostic favorable (1.20e-4)" "unprognostic (5.27e-2)" "unprognostic (6.94e-2)" "unprognostic (6.59e-3)" "unprognostic (6.42e-3)" "unprognostic (3.16e-2)" "unprognostic (2.10e-1)" "unprognostic (1.37e-2)" "unprognostic (1.08e-3)" "unprognostic (4.52e-2)" "unprognostic (2.03e-1)" RNF166 "MGC14381, MGC2647" ENSG00000158717 "Ring finger protein 166" Q96A37 16 88696499-88706408 "Enzymes, Predicted intracellular proteins" "Autophagy, Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 86.0;lymphoid tissue: 98.5" "Cell type enhanced" "Detected in many" "cDC: 49.6;Hofbauer cells: 46.4;Macrophages: 45.4;Microglia: 65.4;Monocyte progenitors: 48.5;monocytes: 67.9;Neutrophil progenitors: 70.5;Neutrophils: 153.0;NK-cells: 82.2;T-cells: 60.4" "Group enriched" "Detected in all" 5 "central nervous system macrophage: 79.8;leukocyte: 84.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - T-cells, Breast - T-cells, Prostate - T-cells, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042970 Approved "Nucleoplasm,Plasma membrane,Cytosol" No No "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 18 Nucleoplasm "Plasma membrane, Cytosol" "HPA042970: " "unprognostic (2.92e-1)" "unprognostic (2.50e-2)" "unprognostic (6.93e-2)" "unprognostic (2.92e-1)" "unprognostic (6.87e-3)" "unprognostic (2.85e-1)" "unprognostic (1.10e-1)" "unprognostic (3.19e-2)" "unprognostic (1.64e-2)" "unprognostic (7.79e-2)" "potential prognostic unfavorable (1.32e-4)" "unprognostic (1.12e-1)" "unprognostic (2.76e-2)" "unprognostic (3.99e-2)" "unprognostic (4.62e-3)" "unprognostic (6.96e-3)" "unprognostic (4.52e-1)" "unprognostic (7.28e-2)" "unprognostic (4.20e-1)" "unprognostic (7.49e-2)" "unprognostic (3.68e-3)" "potential prognostic favorable (1.72e-4)" "unprognostic (4.06e-2)" "unprognostic (1.79e-1)" "unprognostic (1.34e-1)" "unprognostic (7.21e-2)" "unprognostic (1.44e-1)" "unprognostic (3.89e-1)" "unprognostic (6.77e-2)" "unprognostic (1.45e-2)" "unprognostic (1.18e-2)" RNF167 DKFZP566H073 ENSG00000108523 "Ring finger protein 167" Q9H6Y7 17 4940008-4945222 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 213.6;Extravillous trophoblasts: 182.3;Oocytes: 285.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049810 Approved Approved "Vesicles,Mitotic spindle,Centriolar satellite,Cytosol" Yes NA "Cluster 45: Eosinophils - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 23 "Vesicles, Cytosol" "Mitotic spindle, Centriolar satellite" "HPA049810: " "unprognostic (1.48e-1)" "unprognostic (6.74e-2)" "unprognostic (1.24e-3)" "unprognostic (3.84e-2)" "unprognostic (4.06e-2)" "unprognostic (1.51e-1)" "unprognostic (2.21e-2)" "unprognostic (4.95e-2)" "unprognostic (4.14e-2)" "unprognostic (8.13e-2)" "unprognostic (1.37e-2)" "unprognostic (1.28e-2)" "potential prognostic favorable (2.50e-5)" "unprognostic (6.14e-2)" "unprognostic (2.56e-1)" "unprognostic (8.25e-2)" "unprognostic (6.85e-2)" "potential prognostic favorable (2.66e-4)" "unprognostic (2.85e-1)" "unprognostic (3.76e-3)" "unprognostic (3.66e-2)" "potential prognostic favorable (3.05e-6)" "unprognostic (3.51e-1)" "unprognostic (1.13e-1)" "unprognostic (1.39e-2)" "unprognostic (7.08e-2)" "unprognostic (9.04e-2)" "unprognostic (2.10e-1)" "unprognostic (3.59e-1)" "unprognostic (2.30e-1)" "unprognostic (2.99e-1)" RNF168 FLJ35794 ENSG00000163961 "Ring finger protein 168" Q8IYW5 3 196468783-196503768 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 312.1;Late spermatids: 734.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046109 Enhanced "Nucleoplasm,Nuclear bodies" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 34 Nucleoplasm "Nuclear bodies" "HPA046109: " "unprognostic (2.27e-2)" "unprognostic (2.39e-3)" "unprognostic (1.20e-1)" "unprognostic (1.69e-1)" "unprognostic (2.22e-1)" "unprognostic (2.25e-1)" "unprognostic (2.50e-1)" "unprognostic (9.72e-2)" "unprognostic (7.03e-2)" "unprognostic (3.18e-3)" "potential prognostic favorable (3.39e-4)" "unprognostic (1.20e-2)" "unprognostic (5.36e-2)" "unprognostic (3.21e-3)" "unprognostic (6.20e-3)" "unprognostic (2.28e-3)" "unprognostic (3.46e-2)" "unprognostic (1.09e-1)" "unprognostic (4.47e-3)" "unprognostic (1.86e-1)" "unprognostic (2.08e-1)" "potential prognostic unfavorable (8.94e-4)" "unprognostic (4.54e-2)" "unprognostic (1.13e-2)" "unprognostic (3.49e-2)" "unprognostic (1.89e-2)" "unprognostic (3.76e-2)" "unprognostic (3.86e-2)" "unprognostic (1.46e-1)" "unprognostic (1.93e-2)" "unprognostic (7.80e-2)" RNF169 KIAA1991 ENSG00000166439 "Ring finger protein 169" Q8NCN4 11 74748849-74842413 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 380.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038505, HPA046138, HPA047952" Uncertain Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Nuclear bodies,Cytosol" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 61: Non-specific - Transcription" "Cluster 46: Brainstem - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 16 "Nucleoplasm, Nuclear bodies" "Nucleoli, Nucleoli rim, Cytosol" "HPA038505: , HPA046138: , HPA047952: " "unprognostic (3.14e-2)" "unprognostic (1.21e-1)" "unprognostic (1.33e-3)" "unprognostic (2.42e-2)" "unprognostic (2.27e-1)" "unprognostic (2.77e-3)" "unprognostic (8.71e-2)" "unprognostic (6.28e-2)" "unprognostic (4.53e-2)" "potential prognostic unfavorable (5.05e-4)" "potential prognostic favorable (3.17e-5)" "unprognostic (4.09e-3)" "unprognostic (1.65e-1)" "unprognostic (2.75e-2)" "unprognostic (3.46e-1)" "unprognostic (2.29e-1)" "unprognostic (4.72e-2)" "unprognostic (3.62e-2)" "unprognostic (3.04e-2)" "unprognostic (5.24e-2)" "unprognostic (1.72e-1)" "unprognostic (4.44e-3)" "unprognostic (4.29e-2)" "unprognostic (1.47e-1)" "unprognostic (1.93e-2)" "potential prognostic favorable (1.98e-4)" "unprognostic (1.95e-1)" "unprognostic (3.34e-1)" "unprognostic (1.57e-1)" "unprognostic (1.45e-2)" "unprognostic (4.03e-3)" RNF17 "FLJ11045, Mmip-2, SPATA23, TDRD4" ENSG00000132972 "Ring finger protein 17" Q9BXT8 13 24764169-24879921 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "testis: 22.7" "Group enriched" "Detected in some" 4 "Differentiating spermatogonia: 70.5;Early primary spermatocytes: 131.8;Early spermatids: 39.6;Late primary spermatocytes: 60.3;Late spermatids: 48.0;Oocytes: 73.7;Undifferentiated spermatogonia: 70.0" "Low cell type specificity" "Detected in some" "Cancer enriched" "Detected in single" 48 "Testicular Germ Cell Tumor (TCGA): 11.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 1.6;thyroid cancer: 2.0" "Testis - Spermatocytes" "Not detected" "Not detected" "Region enriched" "Detected in single" 13 "olfactory bulb: 1.9" "HPA039699, HPA040111" Approved NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" "HPA039699: , HPA040111: " "unprognostic (3.08e-1)" RNF170 "ADSA, DKFZP564A022, SNAX1" ENSG00000120925 "Ring finger protein 170" Q96K19 8 42849637-42897290 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Host-virus interaction, Ubl conjugation pathway" Transferase "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050931, HPA054621" Uncertain NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 12 "HPA050931: , HPA054621: " "unprognostic (6.29e-2)" "unprognostic (1.60e-2)" "unprognostic (5.50e-3)" "unprognostic (9.16e-3)" "unprognostic (2.14e-1)" "unprognostic (1.56e-1)" "unprognostic (3.76e-3)" "unprognostic (3.11e-1)" "unprognostic (1.19e-1)" "unprognostic (1.36e-2)" "potential prognostic favorable (4.52e-6)" "unprognostic (3.50e-2)" "unprognostic (4.38e-2)" "unprognostic (2.88e-1)" "unprognostic (1.59e-2)" "unprognostic (9.82e-2)" "unprognostic (6.98e-2)" "unprognostic (1.65e-1)" "unprognostic (1.53e-1)" "unprognostic (1.32e-1)" "potential prognostic unfavorable (4.79e-5)" "unprognostic (2.24e-1)" "unprognostic (1.89e-1)" "unprognostic (6.02e-2)" "unprognostic (2.22e-1)" "unprognostic (3.92e-1)" "unprognostic (1.04e-1)" "unprognostic (8.96e-2)" "unprognostic (2.50e-1)" "unprognostic (4.35e-2)" "unprognostic (5.75e-2)" RNF175 FLJ34190 ENSG00000145428 "Ring finger protein 175" Q8N4F7 4 153710160-153760024 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 26.0" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 85.8;Brain inhibitory neurons: 111.7;Early spermatids: 63.2;Late primary spermatocytes: 65.0;Neutrophils: 87.2;Oligodendrocyte progenitor cells: 49.4;Other brain neurons: 96.5;Pituitary stem cells: 366.6;Retinal ganglion cells: 50.2" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 8.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.4" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Bone cancer: 4.4;skin cancer: 3.9" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Kidney - Macrophages, Liver - Neutrophils, Lung - Neutrophils_2, Pituitary gland - Undifferentiated cells (Pituitary gland), Prostate - Fibroblasts, Spleen - Neutrophils_2, Testis - Early spermatids, Testis - Late spermatids" HPA035837 Uncertain NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 1: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 2 "HPA035837: " "unprognostic (6.25e-2)" "unprognostic (1.94e-1)" "unprognostic (9.48e-3)" "potential prognostic unfavorable (1.54e-4)" "unprognostic (2.66e-1)" "unprognostic (1.63e-1)" "unprognostic (3.18e-2)" "potential prognostic unfavorable (1.76e-5)" "unprognostic (3.92e-3)" "unprognostic (4.51e-2)" "unprognostic (9.62e-3)" "potential prognostic favorable (5.88e-4)" "unprognostic (9.45e-2)" "unprognostic (2.15e-1)" "unprognostic (8.34e-2)" "unprognostic (4.32e-2)" "unprognostic (1.81e-1)" "unprognostic (2.49e-1)" "unprognostic (1.90e-1)" "unprognostic (1.05e-1)" RNF180 ENSG00000164197 "Ring finger protein 180" Q86T96 5 64165843-64372869 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 23.8" "Cell type enhanced" "Detected in many" "Lactotrophs: 249.2;Oligodendrocyte progenitor cells: 227.3;Somatotrophs: 203.8;Thyrotrophs: 223.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 13.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Adrenal gland - Fibroblasts, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006897 Approved Approved Cytosol NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 62: Smooth muscle cells - Muscle contraction" 6 Cytosol "HPA006897: " "unprognostic (1.94e-1)" "unprognostic (4.14e-2)" "unprognostic (4.07e-2)" "unprognostic (1.03e-1)" "unprognostic (6.38e-2)" "unprognostic (3.08e-1)" "validated prognostic favorable (5.68e-5)" "validated prognostic favorable (4.21e-6)" "unprognostic (2.17e-2)" "potential prognostic favorable (3.38e-5)" "unprognostic (1.26e-3)" "unprognostic (5.22e-2)" "unprognostic (1.26e-3)" "unprognostic (4.97e-2)" "unprognostic (1.60e-1)" "potential prognostic unfavorable (1.05e-4)" "unprognostic (6.10e-3)" "unprognostic (9.25e-2)" "unprognostic (1.60e-1)" "unprognostic (1.76e-1)" "unprognostic (2.90e-1)" "unprognostic (1.80e-2)" "unprognostic (4.39e-1)" "unprognostic (1.17e-2)" "unprognostic (1.89e-1)" RNF181 HSPC238 ENSG00000168894 "Ring finger protein 181" Q9P0P0 2 85595725-85597708 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 395.1;Esophageal apical cells: 678.5;Esophageal suprabasal cells: 351.2;Extravillous trophoblasts: 341.8;Late primary spermatocytes: 376.2;Late spermatids: 345.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "HPA046112, HPA062121" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 27: Non-specific - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 8: Non-specific - Secretory pathway" 19 Nucleoplasm Cytosol "HPA046112: , HPA062121: " "unprognostic (1.82e-2)" "unprognostic (9.81e-2)" "unprognostic (4.81e-2)" "unprognostic (6.40e-3)" "unprognostic (1.22e-1)" "unprognostic (9.51e-2)" "unprognostic (3.30e-2)" "unprognostic (2.79e-1)" "unprognostic (3.72e-3)" "unprognostic (9.38e-2)" "unprognostic (7.04e-2)" "unprognostic (1.58e-2)" "unprognostic (5.20e-2)" "unprognostic (2.75e-2)" "unprognostic (2.05e-2)" "unprognostic (1.53e-1)" "unprognostic (1.34e-1)" "potential prognostic favorable (6.06e-4)" "unprognostic (1.14e-1)" "unprognostic (1.17e-1)" "unprognostic (2.12e-2)" "unprognostic (1.02e-1)" "unprognostic (2.84e-2)" "unprognostic (1.90e-1)" "unprognostic (9.04e-2)" "unprognostic (3.67e-1)" "unprognostic (2.79e-1)" "unprognostic (4.23e-2)" "unprognostic (1.26e-1)" "unprognostic (1.36e-2)" "unprognostic (7.44e-2)" RNF182 MGC33993 ENSG00000180537 "Ring finger protein 182" Q8N6D2 6 13924446-13980310 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 8.0;brain: 15.9;retina: 8.1" "Cell type enhanced" "Detected in many" "Astrocytes: 96.9;Bergmann glia: 232.2;Choroid plexus epithelial cells: 65.3;Ependymal cells: 37.9;Retinal bipolar cells: 45.8;Retinal horizontal cells: 36.1;Somatotrophs: 49.8;Thyrotrophs: 50.9" "Cell type enhanced" "Detected in many" "Bergmann glia: 267.8" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 11.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 43.2" "Adipose visceral - Mesothelial cells, Breast - Endothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Spleen - Erythrocytes, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012309 Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 28: Astrocytes - Homeostasis & neuron support" 8 "Nucleoplasm, Golgi apparatus" Vesicles "HPA012309: " "unprognostic (1.46e-3)" "unprognostic (2.84e-2)" "unprognostic (9.91e-2)" "unprognostic (1.90e-1)" "unprognostic (7.46e-2)" "unprognostic (8.30e-3)" "unprognostic (2.54e-1)" "unprognostic (2.83e-1)" "unprognostic (1.60e-1)" "unprognostic (8.82e-3)" "unprognostic (3.82e-3)" "unprognostic (7.46e-3)" "unprognostic (1.59e-1)" "unprognostic (2.07e-1)" "unprognostic (1.31e-1)" "unprognostic (1.82e-2)" "unprognostic (2.59e-2)" "unprognostic (3.07e-2)" "unprognostic (6.00e-3)" RNF183 MGC4734 ENSG00000165188 "Ring finger protein 183" Q96D59 9 113297093-113303376 "Enzymes, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 15.3;kidney: 9.3" "Cell type enhanced" "Detected in many" "Endometrial luminal cells: 39.5;Epididymal efferent duct absorptive cells: 20.6;Epididymal efferent duct ciliated cells: 40.3;Epididymal principal cells: 53.9;Esophageal apical cells: 22.9;Mucous neck cells: 15.6;Proximal tubule cells: 30.9" "Cell type enhanced" "Detected in single" "Bergmann glia: 1.9" "Cancer enriched" "Detected in many" 4 "Uterine Corpus Endometrial Carcinoma (TCGA): 26.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 2.2" "Lung - Respiratory ciliated cells, Prostate - Urothelial cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA057675 Uncertain NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 35 "HPA057675: " "unprognostic (8.23e-2)" "unprognostic (1.37e-2)" "unprognostic (2.09e-2)" "unprognostic (3.11e-2)" "unprognostic (4.09e-2)" "unprognostic (6.74e-2)" "unprognostic (4.51e-2)" "validated prognostic favorable (8.60e-6)" "validated prognostic favorable (5.38e-5)" "unprognostic (5.43e-3)" "unprognostic (5.75e-2)" "unprognostic (2.39e-1)" "unprognostic (2.25e-2)" "unprognostic (5.04e-3)" "unprognostic (9.74e-2)" "unprognostic (3.21e-1)" "unprognostic (3.80e-1)" "unprognostic (8.60e-2)" "unprognostic (8.49e-3)" "unprognostic (3.04e-3)" "unprognostic (6.71e-2)" "unprognostic (2.03e-1)" "unprognostic (1.89e-1)" "unprognostic (1.99e-1)" RNF185 FLJ38628 ENSG00000138942 "Ring finger protein 185" Q96GF1 22 31160182-31207019 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Autophagy, Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 152.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Prostate - Prostate glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 66: Non-specific - Mitochondria" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 100 "unprognostic (9.53e-2)" "unprognostic (1.64e-1)" "unprognostic (2.36e-1)" "unprognostic (1.25e-1)" "unprognostic (2.89e-1)" "unprognostic (1.20e-1)" "unprognostic (3.15e-3)" "unprognostic (4.98e-2)" "unprognostic (1.39e-1)" "unprognostic (5.41e-2)" "potential prognostic favorable (9.25e-11)" "unprognostic (9.75e-3)" "unprognostic (1.13e-1)" "unprognostic (2.70e-2)" "unprognostic (2.04e-1)" "unprognostic (1.11e-1)" "unprognostic (2.12e-1)" "unprognostic (1.66e-1)" "unprognostic (3.54e-3)" "unprognostic (1.37e-1)" "unprognostic (3.20e-3)" "unprognostic (1.55e-1)" "unprognostic (3.83e-1)" "unprognostic (7.88e-2)" "unprognostic (2.40e-2)" "unprognostic (8.15e-2)" "unprognostic (5.84e-2)" "unprognostic (8.29e-2)" "unprognostic (1.10e-1)" "unprognostic (1.02e-1)" "unprognostic (2.88e-1)" RNF186 FLJ20225 ENSG00000178828 "Ring finger protein 186" Q9NXI6 1 19814029-19815283 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 63.5;intestine: 123.3;pancreas: 41.6" "Cell type enhanced" "Detected in some" "Colonocytes: 81.2;Enteric stem cells: 128.6;Enteric transient amplifying cells: 90.8;Epididymal principal cells: 331.2;Goblet cells: 35.2;Neuroendocrine cells: 64.1;Paneth cells: 46.4;Tuft cells: 46.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 25.1;Kidney Renal Clear Cell Carcinoma (TCGA): 29.7;Rectum Adenocarcinoma (TCGA): 26.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 3.2;ovarian cancer: 1.0" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" "Not detected" "Not detected" "HPA034547, HPA035558" Enhanced NA NA "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 4 "HPA034547: , HPA035558: " "unprognostic (1.78e-1)" "unprognostic (2.59e-1)" "unprognostic (2.59e-1)" "unprognostic (1.83e-1)" "unprognostic (2.15e-3)" "potential prognostic favorable (1.45e-6)" "unprognostic (1.41e-3)" "unprognostic (7.37e-2)" "unprognostic (1.29e-1)" "unprognostic (2.42e-1)" "unprognostic (1.02e-1)" "unprognostic (2.39e-1)" "unprognostic (1.14e-1)" "unprognostic (1.92e-1)" RNF187 "RACO-1, RACO1" ENSG00000168159 "Ring finger protein 187" Q5TA31 1 228487382-228499899 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bergmann glia: 16.2;Brain excitatory neurons: 33.1;Brain inhibitory neurons: 29.7;Ependymal cells: 22.9;Loop of henle epithelial cells: 10.3;Oligodendrocyte progenitor cells: 15.7;Oligodendrocytes: 21.5;Other brain neurons: 44.5;Papillary tip epithelial cells: 12.8;Podocytes: 17.3;Renal collecting duct principal cells: 10.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 3.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" HPA030098 Approved Supported Nucleoplasm,Cytosol Yes No "Cluster 45: Eosinophils - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 13: Non-specific - Mixed function" "Cluster 98: Neurons - Neurotransmission & signaling" 12 "Nucleoplasm, Cytosol" "HPA030098: " "unprognostic (1.32e-1)" "unprognostic (1.97e-3)" "unprognostic (5.40e-2)" "unprognostic (4.26e-3)" "unprognostic (1.44e-1)" "unprognostic (5.28e-3)" "unprognostic (1.56e-1)" "unprognostic (4.72e-1)" "unprognostic (6.79e-2)" "unprognostic (2.90e-2)" "potential prognostic favorable (2.15e-4)" "unprognostic (1.40e-1)" "unprognostic (5.89e-2)" "unprognostic (6.77e-2)" "unprognostic (5.91e-3)" "unprognostic (1.56e-1)" "unprognostic (1.84e-3)" "unprognostic (1.79e-1)" "unprognostic (1.16e-1)" "unprognostic (2.04e-2)" "unprognostic (4.96e-2)" "unprognostic (4.71e-2)" "unprognostic (1.68e-1)" "unprognostic (1.63e-2)" "unprognostic (6.19e-2)" "unprognostic (3.02e-1)" "unprognostic (3.20e-1)" "unprognostic (2.43e-1)" "unprognostic (4.15e-1)" "unprognostic (7.43e-3)" "unprognostic (3.20e-2)" RNF19A "DKFZp566B1346, dorfin, RNF19" ENSG00000034677 "Ring finger protein 19A, RBR E3 ubiquitin protein ligase" Q9NV58 8 100257060-100336218 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 1004.5;T-cells: 702.4;Urothelial cells: 897.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011455, HPA023652" Approved NA NA "Cluster 24: Non-specific - Transcription" "Cluster 39: Testis - Nuclear processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 51: Secretory epithelial cells - Mixed function" 6 "CAB011455: , HPA023652: " "unprognostic (1.54e-3)" "unprognostic (7.47e-2)" "unprognostic (8.66e-2)" "unprognostic (9.64e-2)" "unprognostic (1.76e-1)" "unprognostic (8.09e-2)" "unprognostic (3.72e-1)" "unprognostic (6.10e-2)" "unprognostic (1.27e-2)" "unprognostic (3.97e-3)" "unprognostic (2.78e-2)" "potential prognostic favorable (6.25e-4)" "unprognostic (4.16e-2)" "unprognostic (7.41e-2)" "unprognostic (5.20e-2)" "unprognostic (2.28e-1)" "potential prognostic unfavorable (5.64e-4)" "unprognostic (1.64e-3)" "unprognostic (2.99e-1)" "unprognostic (2.68e-3)" "unprognostic (7.19e-3)" "unprognostic (8.24e-2)" "potential prognostic unfavorable (2.84e-4)" "unprognostic (9.72e-2)" "unprognostic (2.33e-2)" "potential prognostic favorable (3.97e-4)" "unprognostic (1.14e-1)" "unprognostic (3.34e-1)" "unprognostic (1.54e-1)" "unprognostic (7.76e-2)" "unprognostic (5.79e-2)" RNF19B "FLJ90005, IBRDC3, NKLAM" ENSG00000116514 "Ring finger protein 19B" Q6ZMZ0 1 32936445-32964809 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 73.9" "Cell type enriched" "Detected in many" 4 "Neutrophils: 1022.8" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 67.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 16.9" "Lineage enriched" "Detected in all" 8 "granulocytes: 16.9" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049587, HPA063640" Approved Approved Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 25: Non-specific - Transcription" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 33 Cytosol "HPA049587: , HPA063640: " "unprognostic (9.31e-2)" "unprognostic (3.84e-2)" "unprognostic (1.36e-1)" "unprognostic (2.08e-1)" "unprognostic (4.72e-3)" "unprognostic (9.65e-2)" "unprognostic (8.01e-2)" "unprognostic (5.98e-2)" "unprognostic (6.19e-3)" "unprognostic (1.15e-1)" "potential prognostic favorable (5.49e-9)" "unprognostic (2.65e-3)" "unprognostic (1.56e-2)" "potential prognostic unfavorable (6.11e-6)" "unprognostic (1.12e-1)" "unprognostic (7.35e-2)" "unprognostic (5.45e-2)" "unprognostic (8.23e-2)" "unprognostic (1.97e-1)" "unprognostic (2.91e-1)" "unprognostic (2.81e-2)" "unprognostic (1.44e-1)" "unprognostic (7.62e-2)" "unprognostic (2.35e-1)" "unprognostic (3.40e-1)" "unprognostic (2.02e-2)" "unprognostic (1.98e-1)" "unprognostic (5.48e-2)" "unprognostic (1.19e-1)" "unprognostic (3.34e-1)" "unprognostic (3.98e-1)" RNF2 "BAP-1, BAP1, DING, HIPI3, RING1B, RING2" ENSG00000121481 "Ring finger protein 2" Q99496 1 185045526-185102603 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Repressor, Transferase" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 116.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026803 Uncertain Enhanced "Nucleoplasm,Nuclear bodies" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" 181 Nucleoplasm "Nuclear bodies" "HPA026803: " "unprognostic (9.87e-2)" "unprognostic (1.52e-1)" "unprognostic (1.01e-1)" "potential prognostic unfavorable (2.75e-4)" "unprognostic (1.82e-1)" "unprognostic (2.86e-2)" "unprognostic (2.96e-2)" "unprognostic (2.78e-1)" "unprognostic (2.72e-1)" "potential prognostic unfavorable (3.41e-5)" "potential prognostic favorable (7.70e-4)" "unprognostic (2.78e-2)" "potential prognostic unfavorable (9.10e-4)" "potential prognostic unfavorable (3.67e-4)" "unprognostic (2.52e-3)" "unprognostic (3.71e-3)" "unprognostic (1.77e-2)" "unprognostic (2.98e-2)" "unprognostic (3.09e-1)" "unprognostic (5.78e-2)" "unprognostic (2.44e-3)" "unprognostic (9.42e-3)" "unprognostic (2.29e-3)" "unprognostic (1.42e-1)" "unprognostic (2.63e-1)" "unprognostic (1.15e-1)" "unprognostic (1.73e-2)" "unprognostic (2.39e-2)" "unprognostic (8.07e-2)" "unprognostic (1.11e-2)" "unprognostic (7.68e-2)" RNF20 "BRE1, BRE1A, FLJ11189, FLJ20382, hBRE1, KAIA2779" ENSG00000155827 "Ring finger protein 20" Q5VTR2 9 101533853-101563344 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 154.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Kidney - Fibroblasts, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012478, HPA029442, HPA051773" Supported Enhanced Nucleoplasm,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 58 Nucleoplasm Cytosol "CAB012478: , HPA029442: , HPA051773: " "unprognostic (8.53e-2)" "unprognostic (2.40e-2)" "unprognostic (1.05e-1)" "unprognostic (1.26e-1)" "unprognostic (1.69e-1)" "unprognostic (1.32e-2)" "unprognostic (1.36e-2)" "unprognostic (2.78e-1)" "unprognostic (2.67e-1)" "unprognostic (1.16e-2)" "validated prognostic favorable (3.07e-10)" "validated prognostic favorable (3.41e-5)" "unprognostic (1.07e-1)" "unprognostic (3.08e-3)" "unprognostic (8.12e-2)" "unprognostic (1.83e-1)" "unprognostic (4.07e-1)" "unprognostic (1.21e-1)" "unprognostic (2.03e-2)" "unprognostic (7.49e-2)" "unprognostic (6.33e-3)" "unprognostic (3.31e-2)" "unprognostic (9.49e-2)" "unprognostic (1.55e-1)" "unprognostic (2.77e-2)" "unprognostic (7.93e-2)" "unprognostic (2.07e-1)" "unprognostic (8.64e-2)" "unprognostic (2.75e-1)" "unprognostic (1.28e-1)" "unprognostic (3.88e-2)" RNF207 "C1orf188, FLJ32096, FLJ46380" ENSG00000158286 "Ring finger protein 207" Q6ZRF8 1 6205475-6221299 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 33.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 178.5;Salivary duct cells: 57.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA028378, HPA042535" Uncertain Approved Cytosol NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 1 Cytosol "HPA028378: , HPA042535: " "unprognostic (1.11e-1)" "unprognostic (3.43e-2)" "unprognostic (4.61e-2)" "unprognostic (2.52e-2)" "unprognostic (2.83e-3)" "unprognostic (2.54e-2)" "unprognostic (5.02e-2)" "unprognostic (5.23e-3)" "unprognostic (3.27e-2)" "potential prognostic unfavorable (1.13e-6)" "unprognostic (2.53e-1)" "unprognostic (3.41e-2)" "unprognostic (9.32e-2)" "unprognostic (1.36e-1)" "unprognostic (8.35e-2)" "unprognostic (1.87e-1)" "unprognostic (2.96e-2)" "unprognostic (9.87e-2)" "unprognostic (9.69e-2)" "unprognostic (4.23e-2)" "unprognostic (7.69e-2)" "unprognostic (1.59e-2)" "unprognostic (8.70e-2)" "unprognostic (2.25e-1)" "unprognostic (9.36e-3)" "unprognostic (1.86e-1)" "unprognostic (3.30e-2)" RNF208 DKFZP761H1710 ENSG00000212864 "Ring finger protein 208" Q9H0X6 9 137220247-137222240 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 133.5" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 86.3;Parietal cells: 23.0;Platelets: 67.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021256, HPA021429" Uncertain Enhanced Nucleoplasm NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 21 Nucleoplasm "HPA021256: , HPA021429: " "unprognostic (1.35e-1)" "unprognostic (7.92e-2)" "unprognostic (2.46e-1)" "unprognostic (1.63e-1)" "unprognostic (1.74e-2)" "unprognostic (1.82e-1)" "unprognostic (6.85e-3)" "unprognostic (2.45e-1)" "unprognostic (5.34e-3)" "unprognostic (3.33e-3)" "potential prognostic favorable (2.73e-5)" "unprognostic (3.01e-3)" "unprognostic (5.42e-3)" "potential prognostic unfavorable (5.14e-4)" "unprognostic (2.83e-1)" "unprognostic (1.40e-1)" "unprognostic (7.44e-2)" "unprognostic (7.22e-2)" "unprognostic (4.58e-3)" "unprognostic (1.13e-1)" "unprognostic (6.26e-2)" "unprognostic (8.32e-3)" "unprognostic (7.94e-3)" "unprognostic (1.19e-1)" "unprognostic (1.91e-1)" "unprognostic (1.94e-1)" "unprognostic (8.89e-2)" "unprognostic (2.38e-1)" "unprognostic (3.36e-1)" "unprognostic (2.00e-2)" "unprognostic (9.39e-2)" RNF212 "FLJ38841, LOC285498" ENSG00000178222 "Ring finger protein 212" Q495C1 4 1056250-1113564 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Meiosis, Ubl conjugation pathway" Transferase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "pancreas: 8.5" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 42.3;Early primary spermatocytes: 71.3;Gonadotrophs: 42.3;Lactotrophs: 68.1;Loop of henle epithelial cells: 41.6;Oocytes: 73.7;Somatotrophs: 49.3;Undifferentiated spermatogonia: 46.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 11.2;Ovary Serous Cystadenocarcinoma (TCGA): 10.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 24.9;Gallbladder cancer: 27.8" "Skeletal muscle - Fibroblasts" "Not detected" "Not detected" "Not detected" "Not detected" HPA057527 Uncertain NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 8: Pancreas - Proteolysis" "Cluster 15: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" "HPA057527: " "unprognostic (2.38e-2)" "unprognostic (6.43e-2)" "unprognostic (2.18e-2)" "unprognostic (3.09e-1)" "unprognostic (7.78e-3)" "unprognostic (1.30e-2)" "unprognostic (8.90e-2)" "unprognostic (2.76e-1)" "unprognostic (2.66e-1)" "unprognostic (1.03e-1)" "unprognostic (1.25e-2)" "unprognostic (5.18e-2)" "unprognostic (2.06e-1)" "unprognostic (1.46e-1)" "unprognostic (2.66e-2)" "unprognostic (4.77e-3)" "unprognostic (1.74e-2)" "unprognostic (7.63e-2)" "unprognostic (4.03e-2)" "unprognostic (1.89e-2)" "unprognostic (2.99e-1)" "unprognostic (4.61e-2)" "unprognostic (1.83e-1)" RNF212B C14orf164 ENSG00000215277 "Ring finger protein 212B" A8MTL3 14 23185316-23273477 "Essential proteins, Predicted intracellular proteins" Meiosis Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "kidney: 24.2" "Group enriched" "Detected in many" 6 "Early primary spermatocytes: 155.1;Proximal tubule cells: 490.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Testis - Spermatocytes" "Not detected" "Not detected" "HPA053574, HPA064430" Uncertain Approved "Nucleoplasm,Nucleoli,Nucleoli fibrillar center,Golgi apparatus" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 51: Neurons - Mixed function" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 88: Proximal tubular cells - Transmembrane transport" "Golgi apparatus" "Nucleoplasm, Nucleoli, Nucleoli fibrillar center" "HPA053574: , HPA064430: " "unprognostic (1.51e-1)" RNF213 "ALO17, C17orf27, KIAA1554, KIAA1618, MYMY2, NET57" ENSG00000173821 "Ring finger protein 213" Q63HN8 17 80260852-80398794 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Immunity, Lipid metabolism, Ubl conjugation pathway" "Hydrolase, Multifunctional enzyme, Transferase" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 684.1;Neutrophils: 659.8" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 373.0;leukocyte: 508.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003347, HPA026790" Approved Supported Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 13 Cytosol "HPA003347: , HPA026790: " "unprognostic (1.63e-2)" "unprognostic (3.64e-2)" "unprognostic (1.25e-2)" "unprognostic (5.25e-3)" "unprognostic (2.05e-1)" "unprognostic (3.87e-2)" "unprognostic (2.83e-1)" "unprognostic (2.46e-1)" "unprognostic (4.76e-2)" "unprognostic (1.47e-3)" "potential prognostic favorable (1.13e-4)" "unprognostic (2.79e-3)" "unprognostic (1.73e-2)" "unprognostic (1.38e-1)" "unprognostic (3.26e-2)" "unprognostic (1.30e-1)" "unprognostic (1.82e-2)" "unprognostic (2.16e-1)" "unprognostic (1.41e-1)" "unprognostic (1.85e-1)" "unprognostic (6.77e-3)" "unprognostic (1.14e-3)" "unprognostic (5.01e-2)" "unprognostic (1.60e-1)" "unprognostic (7.65e-3)" "potential prognostic favorable (4.91e-5)" "unprognostic (1.05e-1)" "unprognostic (7.85e-2)" "unprognostic (7.25e-2)" "unprognostic (2.91e-2)" "unprognostic (4.19e-2)" RNF214 DKFZp547C195 ENSG00000167257 "Ring finger protein 214" Q8ND24 11 117232625-117286454 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "T-reg: 20.6" "Group enriched" "Detected in all" 5 "granulocytes: 6.4;T-cells: 20.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039332 Approved Approved "Golgi apparatus,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 21: Testis - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 24: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 13 "Golgi apparatus, Cytosol" "HPA039332: " "unprognostic (1.33e-1)" "unprognostic (3.62e-2)" "unprognostic (1.76e-2)" "unprognostic (1.48e-2)" "unprognostic (2.86e-1)" "unprognostic (1.47e-1)" "unprognostic (3.85e-2)" "unprognostic (2.49e-1)" "unprognostic (1.11e-1)" "unprognostic (2.68e-3)" "potential prognostic favorable (1.96e-4)" "unprognostic (1.21e-3)" "unprognostic (5.81e-3)" "potential prognostic unfavorable (3.63e-4)" "unprognostic (1.80e-1)" "unprognostic (5.58e-2)" "unprognostic (5.02e-3)" "unprognostic (2.41e-1)" "unprognostic (5.01e-2)" "unprognostic (1.32e-1)" "unprognostic (2.47e-1)" "unprognostic (9.07e-3)" "unprognostic (1.84e-3)" "unprognostic (1.54e-1)" "unprognostic (7.14e-3)" "unprognostic (2.83e-2)" "unprognostic (3.85e-3)" "unprognostic (1.77e-1)" "unprognostic (2.94e-1)" "unprognostic (3.31e-1)" "unprognostic (6.14e-2)" RNF215 ENSG00000099999 "Ring finger protein 215" Q9Y6U7 22 30368811-30421771 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epicardial cells: 66.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029427, HPA056498" Approved Approved Nucleoli,Microtubules NA NA "Cluster 24: Non-specific - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 11: Muller glia cells - Retinal homeostasis" 1 Microtubules Nucleoli "HPA029427: , HPA056498: " "unprognostic (1.50e-1)" "unprognostic (1.27e-1)" "unprognostic (2.40e-1)" "unprognostic (3.18e-2)" "unprognostic (5.08e-2)" "unprognostic (3.26e-1)" "unprognostic (2.25e-1)" "unprognostic (1.36e-1)" "unprognostic (1.24e-1)" "unprognostic (6.32e-2)" "potential prognostic unfavorable (1.52e-4)" "unprognostic (2.24e-1)" "unprognostic (1.30e-1)" "unprognostic (4.70e-2)" "unprognostic (1.81e-2)" "unprognostic (8.02e-2)" "unprognostic (3.24e-1)" "unprognostic (2.95e-1)" "unprognostic (8.69e-2)" "unprognostic (1.26e-1)" "unprognostic (7.57e-2)" "unprognostic (2.54e-1)" "unprognostic (3.26e-2)" "unprognostic (2.78e-3)" "unprognostic (5.70e-2)" "unprognostic (1.29e-2)" "unprognostic (2.88e-1)" "unprognostic (2.79e-1)" "unprognostic (2.77e-1)" "unprognostic (1.66e-1)" "unprognostic (2.76e-1)" RNF216 "TRIAD3, UBCE7IP1, ZIN" ENSG00000011275 "Ring finger protein 216" Q9NWF9 7 5620047-5781696 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Ubl conjugation pathway" Transferase "Disease variant, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 421.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018955, HPA021123" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 19: Astrocytes - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 28 Cytosol Nucleoplasm "HPA018955: , HPA021123: " "unprognostic (1.39e-1)" "unprognostic (1.49e-1)" "unprognostic (1.41e-2)" "unprognostic (3.07e-2)" "unprognostic (4.10e-2)" "unprognostic (1.42e-1)" "unprognostic (7.29e-2)" "unprognostic (9.51e-3)" "unprognostic (1.82e-1)" "unprognostic (4.01e-2)" "unprognostic (6.97e-3)" "unprognostic (1.64e-1)" "unprognostic (2.41e-1)" "validated prognostic unfavorable (2.43e-4)" "validated prognostic unfavorable (8.95e-4)" "unprognostic (1.24e-2)" "unprognostic (5.66e-3)" "unprognostic (1.55e-1)" "unprognostic (1.04e-2)" "unprognostic (5.47e-3)" "unprognostic (1.20e-2)" "potential prognostic favorable (2.58e-5)" "unprognostic (8.39e-3)" "unprognostic (1.42e-1)" "unprognostic (3.00e-2)" "unprognostic (1.77e-2)" "unprognostic (9.85e-2)" "unprognostic (2.96e-1)" "unprognostic (4.07e-2)" "unprognostic (2.15e-2)" "unprognostic (8.51e-2)" RNF217 "C6orf172, dJ84N20.1, IBRDC1, MGC26996" ENSG00000146373 "Ring finger protein 217" Q8TC41 6 124962437-125092633 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 39.0" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029598 Uncertain NA NA "Cluster 69: Parathyroid gland - Mixed function" "Cluster 55: Non-specific - Transcription" "Cluster 32: Non-specific - Cell proliferation" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 2 "HPA029598: " "potential prognostic unfavorable (1.14e-5)" "unprognostic (1.45e-2)" "unprognostic (8.84e-2)" "unprognostic (4.39e-2)" "unprognostic (1.25e-1)" "unprognostic (1.56e-1)" "unprognostic (2.36e-1)" "unprognostic (1.75e-2)" "unprognostic (4.44e-2)" "unprognostic (2.00e-1)" "unprognostic (1.53e-3)" "unprognostic (7.86e-3)" "unprognostic (1.47e-1)" "unprognostic (1.62e-2)" "unprognostic (6.42e-3)" "unprognostic (8.22e-3)" "unprognostic (6.09e-3)" "unprognostic (1.41e-1)" "unprognostic (1.10e-1)" "unprognostic (2.15e-2)" "unprognostic (2.63e-1)" "unprognostic (4.19e-2)" "unprognostic (5.93e-2)" "unprognostic (1.20e-1)" "unprognostic (1.19e-1)" "unprognostic (1.01e-2)" "unprognostic (4.20e-2)" "unprognostic (3.87e-3)" "unprognostic (1.86e-1)" "unprognostic (2.31e-2)" "unprognostic (1.57e-1)" RNF220 "C1orf164, FLJ10597" ENSG00000187147 "Ring finger protein 220" Q5VTB9 1 44405194-44651724 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Cardiomyopathy, Deafness, Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "brain: 85.5;skeletal muscle: 22.8" "Cell type enhanced" "Detected in all" "Hematopoietic stem cells: 2462.5;Megakaryocyte progenitors: 485.1;Megakaryocyte-Erythroid progenitors: 1149.7;Oligodendrocytes: 2815.0;Thymocytes: 929.9" "Cell type enhanced" "Detected in all" "fibroblast: 3004.9;oligodendrocyte: 4026.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027577, HPA027578" Approved Supported Nucleoplasm NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 80: Oligodendrocytes - Myelination" 4 Nucleoplasm "HPA027577: , HPA027578: " "unprognostic (5.07e-2)" "unprognostic (6.68e-2)" "unprognostic (3.09e-1)" "unprognostic (4.98e-3)" "unprognostic (2.27e-1)" "unprognostic (2.16e-3)" "unprognostic (3.49e-1)" "unprognostic (8.79e-3)" "potential prognostic unfavorable (9.85e-4)" "unprognostic (2.09e-1)" "unprognostic (3.29e-3)" "unprognostic (9.88e-2)" "unprognostic (1.11e-1)" "validated prognostic unfavorable (7.69e-5)" "validated prognostic unfavorable (4.60e-6)" "unprognostic (8.85e-2)" "unprognostic (1.85e-1)" "unprognostic (3.10e-2)" "unprognostic (4.56e-2)" "unprognostic (2.75e-1)" "unprognostic (3.27e-1)" "unprognostic (3.21e-2)" "unprognostic (5.81e-2)" "unprognostic (1.89e-1)" "unprognostic (1.36e-1)" "unprognostic (1.84e-1)" "unprognostic (4.17e-1)" "unprognostic (1.37e-2)" "unprognostic (1.42e-1)" "unprognostic (1.84e-1)" "unprognostic (2.87e-1)" RNF222 ENSG00000189051 "Ring finger protein 222" A6NCQ9 17 8390702-8397827 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 4.6;esophagus: 16.6;skin 1: 6.7;vagina: 5.7" "Cell type enriched" "Detected in some" 26 "Esophageal apical cells: 203.6" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Head and Neck Squamous Cell Carcinoma (TCGA): 2.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Gallbladder cancer: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA048916 Uncertain NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 25: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" "HPA048916: " "unprognostic (1.74e-2)" RNF223 ENSG00000237330 "Ring finger protein 223" E7ERA6 1 1070967-1074306 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "cervix: 11.1;esophagus: 25.8;vagina: 12.4" "Cell type enriched" "Detected in many" 6 "Esophageal apical cells: 440.6" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 9.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (granular), Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 84: Apical squamous epithelium - Cornification" "unprognostic (2.11e-3)" "unprognostic (2.02e-1)" "unprognostic (9.28e-2)" "unprognostic (1.65e-1)" "unprognostic (3.07e-3)" "unprognostic (2.84e-2)" "unprognostic (3.53e-2)" "unprognostic (1.16e-3)" "unprognostic (1.47e-3)" "unprognostic (8.15e-2)" "unprognostic (2.29e-1)" "unprognostic (3.08e-1)" "unprognostic (1.55e-1)" "unprognostic (2.76e-1)" "unprognostic (2.07e-2)" RNF224 ENSG00000233198 "Ring finger protein 224" P0DH78 9 137227502-137229640 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "esophagus: 3.5;pituitary gland: 5.0" "Cell type enriched" "Detected in some" 6 "Esophageal apical cells: 23.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Pituitary gland - Gonadotropes" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA079078 Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 39: Astrocytes - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" "Nucleoplasm, Golgi apparatus" "HPA079078: " "unprognostic (1.68e-1)" "unprognostic (3.26e-1)" "unprognostic (5.75e-2)" "unprognostic (4.92e-3)" "unprognostic (3.23e-1)" RNF225 ENSG00000269855 "Ring finger protein 225" M0QZC1 19 58395656-58397079 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 2.6;esophagus: 5.6;skin 1: 4.2;vagina: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Head and Neck Squamous Cell Carcinoma (TCGA): 1.4" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "prostate cancer: 1.1" "Minor Salivary Gland - Minor salivary gland basal cells, Skin - Keratinocyte (granular), Testis - Early spermatids" "Low region specificity" "Detected in many" NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" "unprognostic (3.59e-3)" RNF227 LINC02581 ENSG00000179859 "Ring finger protein 227" A6NIN4 17 7913339-7916289 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in all" 6 "skin 1: 61.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 31.7;Suprabasal keratinocytes: 19.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 17.6" "Lineage enriched" "Detected in all" 5 "granulocytes: 17.6" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 37: Skin - Keratinization" "Cluster 2: Neurons - Nucleosome" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 26: Keratinocytes - Keratinization" "unprognostic (2.56e-1)" "unprognostic (8.19e-2)" "unprognostic (2.70e-2)" "unprognostic (1.39e-2)" "unprognostic (2.83e-1)" "unprognostic (1.89e-2)" "unprognostic (9.33e-3)" "unprognostic (1.19e-2)" "unprognostic (6.06e-2)" "unprognostic (2.02e-1)" "potential prognostic favorable (1.87e-4)" "unprognostic (7.83e-2)" "unprognostic (1.24e-1)" "unprognostic (7.23e-2)" "unprognostic (4.80e-2)" "unprognostic (7.46e-2)" "unprognostic (6.71e-2)" "unprognostic (2.87e-1)" "unprognostic (8.48e-2)" "unprognostic (6.24e-2)" "unprognostic (1.67e-1)" "unprognostic (7.60e-2)" "unprognostic (1.67e-1)" "unprognostic (3.85e-2)" "unprognostic (1.72e-1)" "unprognostic (1.75e-1)" "unprognostic (3.09e-2)" "unprognostic (1.64e-1)" RNF24 G1L ENSG00000101236 "Ring finger protein 24" Q9Y225 20 3927309-4015558 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 48.9" "Group enriched" "Detected in many" 4 "Neutrophil progenitors: 1078.4;Neutrophils: 2568.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 239.1" "Lineage enriched" "Detected in all" 10 "granulocytes: 239.1" "Low cancer specificity" "Detected in all" "Liver - Neutrophils, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011900 Approved Supported "Golgi apparatus" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 51: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 2 "Golgi apparatus" "HPA011900: " "unprognostic (7.53e-3)" "unprognostic (1.06e-1)" "unprognostic (3.31e-2)" "unprognostic (1.27e-2)" "unprognostic (1.74e-1)" "unprognostic (1.00e-1)" "unprognostic (6.41e-2)" "unprognostic (3.98e-1)" "unprognostic (1.75e-2)" "unprognostic (2.33e-2)" "unprognostic (2.77e-2)" "unprognostic (8.21e-2)" "unprognostic (2.51e-2)" "potential prognostic unfavorable (1.06e-5)" "unprognostic (1.47e-2)" "unprognostic (3.43e-1)" "unprognostic (2.33e-2)" "unprognostic (6.59e-2)" "unprognostic (2.11e-1)" "unprognostic (1.61e-2)" "unprognostic (2.68e-2)" "unprognostic (1.05e-2)" "unprognostic (2.97e-1)" "unprognostic (2.14e-1)" "unprognostic (3.31e-1)" "unprognostic (1.27e-1)" "unprognostic (1.03e-1)" "unprognostic (1.78e-1)" "unprognostic (1.54e-1)" "unprognostic (1.49e-1)" "unprognostic (1.22e-1)" RNF25 "AO7, FLJ13906" ENSG00000163481 "Ring finger protein 25" Q96BH1 2 218663892-218672002 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036420, HPA036421" Uncertain Approved "Nucleoplasm,Actin filaments,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 24: Non-specific - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 97: Non-specific - Cellular respiration" 32 Cytosol "Nucleoplasm, Actin filaments" "HPA036420: , HPA036421: " "unprognostic (6.72e-3)" "unprognostic (2.06e-1)" "unprognostic (4.10e-2)" "potential prognostic favorable (4.59e-4)" "unprognostic (1.67e-1)" "unprognostic (7.37e-2)" "unprognostic (1.98e-1)" "unprognostic (2.21e-2)" "unprognostic (7.57e-2)" "unprognostic (2.89e-1)" "unprognostic (2.70e-2)" "unprognostic (3.45e-2)" "unprognostic (2.22e-1)" "potential prognostic unfavorable (1.23e-5)" "unprognostic (2.31e-2)" "unprognostic (1.36e-2)" "unprognostic (7.68e-2)" "unprognostic (2.69e-1)" "unprognostic (1.70e-1)" "unprognostic (1.36e-1)" "unprognostic (1.66e-2)" "unprognostic (1.39e-2)" "unprognostic (1.09e-1)" "unprognostic (5.77e-2)" "unprognostic (4.54e-1)" "unprognostic (1.67e-1)" "unprognostic (2.17e-1)" "unprognostic (1.01e-1)" "unprognostic (5.93e-3)" "unprognostic (3.09e-1)" "unprognostic (8.41e-2)" RNF26 MGC2642 ENSG00000173456 "Ring finger protein 26" Q9BY78 11 119334527-119337309 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 49.1;Extravillous trophoblasts: 78.7;Migrating cytotrophoblasts: 60.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Stomach - Mitotic cells (Stomach), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027620 Uncertain Approved Nucleoplasm,Vesicles,Cytosol NA Yes "Cluster 13: Non-specific - Mitochondria" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 45: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 28 Nucleoplasm "Vesicles, Cytosol" "HPA027620: " "unprognostic (2.50e-2)" "unprognostic (1.32e-2)" "unprognostic (3.29e-3)" "unprognostic (2.29e-2)" "unprognostic (4.40e-1)" "unprognostic (9.86e-2)" "unprognostic (2.34e-1)" "unprognostic (2.61e-1)" "unprognostic (7.27e-3)" "unprognostic (3.78e-2)" "potential prognostic favorable (1.18e-4)" "unprognostic (1.09e-1)" "unprognostic (2.92e-3)" "validated prognostic unfavorable (7.10e-5)" "validated prognostic unfavorable (2.99e-5)" "unprognostic (5.99e-3)" "potential prognostic unfavorable (2.20e-4)" "unprognostic (1.16e-1)" "unprognostic (1.15e-2)" "unprognostic (1.76e-1)" "unprognostic (5.68e-2)" "unprognostic (2.26e-2)" "unprognostic (1.82e-1)" "unprognostic (4.53e-2)" "unprognostic (1.11e-2)" "unprognostic (2.93e-1)" "unprognostic (2.69e-2)" "unprognostic (1.98e-1)" "unprognostic (2.20e-1)" "unprognostic (2.04e-1)" "unprognostic (3.11e-2)" RNF31 "FLJ10111, FLJ23501, HOIP, Paul, ZIBRA" ENSG00000092098 "Ring finger protein 31" Q96EP0 14 24146683-24160660 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 7 "Astrocytes: 22.7;Bergmann glia: 15.0;Brain excitatory neurons: 13.8;Brain inhibitory neurons: 12.5;Choroid plexus epithelial cells: 17.5;Ependymal cells: 10.1;Microglia: 21.3;Oligodendrocyte progenitor cells: 15.3;Oligodendrocytes: 15.4;Other brain neurons: 10.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009063, HPA048745" Approved Approved Cytosol NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 24: Non-specific - Transcription" "Cluster 7: Non-specific - Ribosome" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 22: Non-specific - Basic cellular functions" 67 Cytosol "CAB009063: , HPA048745: " "unprognostic (3.64e-1)" "unprognostic (6.37e-3)" "unprognostic (2.51e-1)" "unprognostic (7.61e-2)" "unprognostic (1.18e-1)" "unprognostic (5.35e-2)" "unprognostic (1.94e-1)" "potential prognostic favorable (4.42e-4)" "unprognostic (1.66e-1)" "unprognostic (1.07e-1)" "potential prognostic favorable (1.48e-5)" "unprognostic (4.92e-3)" "unprognostic (2.46e-1)" "unprognostic (8.24e-3)" "unprognostic (2.10e-1)" "unprognostic (3.25e-1)" "potential prognostic unfavorable (2.94e-4)" "unprognostic (1.51e-1)" "unprognostic (3.32e-2)" "unprognostic (6.50e-2)" "unprognostic (7.38e-3)" "unprognostic (7.86e-2)" "unprognostic (5.52e-2)" "unprognostic (1.22e-2)" "unprognostic (2.11e-1)" "unprognostic (8.27e-2)" "unprognostic (8.80e-3)" "unprognostic (1.77e-1)" "unprognostic (4.49e-2)" "unprognostic (4.86e-2)" "unprognostic (3.40e-1)" RNF32 "FKSG33, HSD15, LMBR2" ENSG00000105982 "Ring finger protein 32" Q9H0A6 7 156640281-156677130 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 56.8" "Group enriched" "Detected in many" 4 "Early spermatids: 282.3;Late primary spermatocytes: 550.2;Late spermatids: 780.3" "Cell type enhanced" "Detected in all" "ependymal cell: 31.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 12.5" "Lineage enriched" "Detected in many" 5 "granulocytes: 12.5" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019516, HPA073560" Enhanced Approved "Nuclear bodies,Cytosol" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 57: Testis - Spermatogenesis" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 10 "Nuclear bodies, Cytosol" "HPA019516: , HPA073560: " "unprognostic (1.03e-1)" "unprognostic (3.02e-2)" "unprognostic (1.99e-1)" "unprognostic (3.55e-2)" "potential prognostic unfavorable (9.44e-4)" "unprognostic (1.99e-1)" "unprognostic (4.65e-2)" "unprognostic (1.75e-3)" "unprognostic (4.29e-2)" "unprognostic (1.81e-2)" "unprognostic (2.43e-1)" "unprognostic (7.04e-2)" "unprognostic (2.88e-3)" "unprognostic (1.44e-2)" "unprognostic (2.97e-1)" "unprognostic (1.52e-1)" "unprognostic (6.97e-2)" "unprognostic (4.81e-2)" "unprognostic (3.04e-2)" "unprognostic (3.68e-1)" "unprognostic (2.82e-2)" "unprognostic (1.50e-2)" "unprognostic (1.04e-1)" "unprognostic (2.13e-1)" "unprognostic (2.03e-1)" "unprognostic (1.74e-2)" "unprognostic (3.36e-2)" "unprognostic (5.87e-2)" "potential prognostic unfavorable (2.15e-4)" "unprognostic (5.44e-2)" RNF34 "FLJ21786, RIF, RIFF" ENSG00000170633 "Ring finger protein 34" Q969K3 12 121400083-121430623 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early primary spermatocytes: 257.8;Myonuclei: 197.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074151 Supported "Nucleoplasm,Nuclear speckles,Nuclear bodies" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 55: Myocytes - Oxidative muscle function" 26 Nucleoplasm "Nuclear speckles, Nuclear bodies" "HPA074151: " "unprognostic (1.07e-1)" "unprognostic (8.22e-2)" "unprognostic (2.80e-1)" "unprognostic (3.27e-2)" "unprognostic (6.11e-2)" "unprognostic (1.26e-1)" "unprognostic (1.03e-2)" "unprognostic (2.88e-2)" "unprognostic (1.14e-1)" "unprognostic (1.67e-2)" "unprognostic (1.50e-1)" "unprognostic (9.87e-2)" "unprognostic (6.18e-2)" "potential prognostic unfavorable (5.58e-10)" "unprognostic (1.44e-3)" "unprognostic (7.27e-2)" "unprognostic (8.72e-3)" "unprognostic (5.24e-2)" "unprognostic (8.33e-3)" "unprognostic (1.85e-1)" "unprognostic (1.85e-1)" "unprognostic (2.00e-2)" "unprognostic (1.26e-1)" "unprognostic (8.87e-2)" "unprognostic (3.55e-1)" "unprognostic (8.27e-3)" "unprognostic (9.88e-2)" "unprognostic (2.71e-1)" "unprognostic (1.72e-1)" "unprognostic (1.45e-2)" "unprognostic (1.20e-1)" RNF38 ENSG00000137075 "Ring finger protein 38" Q9H0F5 9 36336396-36487548 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 664.0;Late spermatids: 2377.2;Sertoli cells: 585.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015853 Approved Supported Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 39: Testis - Nuclear processes" "Cluster 16: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 18 Nucleoplasm "HPA015853: " "unprognostic (6.79e-2)" "unprognostic (3.20e-1)" "unprognostic (5.46e-2)" "unprognostic (4.21e-2)" "unprognostic (1.69e-1)" "unprognostic (1.58e-1)" "unprognostic (7.49e-2)" "unprognostic (3.02e-1)" "unprognostic (1.13e-2)" "unprognostic (6.06e-2)" "validated prognostic favorable (2.63e-8)" "validated prognostic favorable (9.56e-5)" "unprognostic (1.74e-1)" "unprognostic (4.13e-3)" "unprognostic (2.26e-1)" "unprognostic (5.92e-2)" "unprognostic (5.90e-2)" "unprognostic (1.90e-1)" "unprognostic (4.56e-2)" "unprognostic (2.98e-1)" "unprognostic (3.30e-1)" "unprognostic (3.88e-1)" "unprognostic (4.43e-2)" "unprognostic (1.41e-1)" "unprognostic (3.00e-2)" "unprognostic (9.22e-2)" "unprognostic (1.99e-1)" "unprognostic (8.99e-3)" "unprognostic (1.30e-1)" "unprognostic (2.17e-1)" "unprognostic (4.97e-2)" RNF39 "FAP216, HZFw1, LIRF" ENSG00000204618 "Ring finger protein 39" Q9H2S5 6 30070266-30075849 "Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 22.1;esophagus: 24.4;skin 1: 63.7;vagina: 22.7" "Cell type enhanced" "Detected in some" "Endometrial secretory cells: 1.9;Ocular epithelial cells: 2.9;Papillary tip epithelial cells: 2.7;Prostatic club cells: 2.2;Prostatic hillock cells: 1.2;Respiratory basal cells: 1.1;Urothelial cells: 3.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose visceral - Mesothelial cells" "Region enhanced" "Detected in many" "cerebral cortex: 8.1" "Group enriched" "Detected in many" 4 "cerebellum: 10.8;cerebral cortex: 9.0;hippocampal formation: 5.1" "CAB019278, HPA047115" Uncertain Approved "Vesicles,Plasma membrane,Centrosome" NA NA "Cluster 58: Skin - Keratinization" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 6 "Vesicles, Plasma membrane, Centrosome" "CAB019278: , HPA047115: " "unprognostic (1.11e-1)" "unprognostic (4.25e-2)" "unprognostic (8.93e-3)" "unprognostic (2.16e-1)" "unprognostic (1.66e-2)" "unprognostic (1.95e-1)" "unprognostic (2.23e-1)" "unprognostic (4.18e-1)" "unprognostic (8.74e-2)" "unprognostic (2.25e-1)" "unprognostic (9.14e-2)" "unprognostic (2.69e-2)" "unprognostic (2.83e-1)" "unprognostic (2.00e-1)" RNF4 "RES4-26, SLX5, SNURF" ENSG00000063978 "Ring finger protein 4" P78317 4 2462220-2515857 "Enzymes, Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - B-cells (Spleen), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022047, HPA049356" Approved Supported "Nucleoplasm,Nuclear bodies,Microtubule ends" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 38: Sub-cortical - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 7: Non-specific - Transcription" 165 "Nucleoplasm, Nuclear bodies" "Microtubule ends" "HPA022047: , HPA049356: " "unprognostic (1.36e-2)" "unprognostic (1.25e-2)" "unprognostic (1.04e-1)" "unprognostic (3.36e-2)" "unprognostic (8.09e-3)" "unprognostic (6.68e-2)" "unprognostic (1.90e-1)" "unprognostic (1.89e-2)" "unprognostic (4.86e-2)" "unprognostic (1.23e-3)" "potential prognostic favorable (8.23e-5)" "unprognostic (3.79e-3)" "unprognostic (6.26e-2)" "unprognostic (2.94e-3)" "unprognostic (7.43e-3)" "unprognostic (2.09e-3)" "potential prognostic unfavorable (7.00e-4)" "unprognostic (7.29e-2)" "unprognostic (1.63e-1)" "unprognostic (2.32e-1)" "unprognostic (7.13e-3)" "unprognostic (2.43e-1)" "unprognostic (1.58e-1)" "unprognostic (6.50e-2)" "unprognostic (4.75e-2)" "unprognostic (3.57e-1)" "unprognostic (1.48e-1)" "unprognostic (2.30e-1)" "unprognostic (1.94e-1)" "unprognostic (2.05e-2)" "unprognostic (2.08e-1)" RNF40 "BRE1B, KIAA0661, RBP95, STARING" ENSG00000103549 "Ring finger protein 40" O75150 16 30761745-30776307 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041330, HPA054227" Approved Supported Nucleoplasm NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 54: Non-specific - Transcription" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 85 Nucleoplasm "HPA041330: , HPA054227: " "unprognostic (2.61e-1)" "unprognostic (5.18e-2)" "unprognostic (2.07e-1)" "unprognostic (4.71e-3)" "unprognostic (4.02e-1)" "unprognostic (2.37e-1)" "unprognostic (3.86e-1)" "unprognostic (1.76e-2)" "unprognostic (2.15e-1)" "unprognostic (9.30e-2)" "potential prognostic favorable (5.90e-6)" "unprognostic (8.96e-3)" "unprognostic (3.95e-2)" "potential prognostic unfavorable (1.72e-4)" "unprognostic (5.11e-3)" "unprognostic (1.08e-1)" "unprognostic (4.70e-3)" "unprognostic (3.69e-1)" "unprognostic (1.27e-1)" "unprognostic (2.61e-1)" "unprognostic (3.22e-1)" "unprognostic (1.80e-1)" "potential prognostic unfavorable (6.72e-4)" "unprognostic (5.49e-2)" "unprognostic (3.54e-2)" "unprognostic (6.40e-2)" "unprognostic (2.38e-1)" "unprognostic (1.91e-1)" "unprognostic (4.13e-1)" "unprognostic (9.78e-3)" "unprognostic (2.48e-1)" RNF41 "NRDP1, SBBI03" ENSG00000181852 "Ring finger protein 41" Q9H4P4 12 56202179-56221933 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Autophagy, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 103.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Prostate - Prostate glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016812 Approved Approved "Nucleoplasm,Nuclear bodies,Midbody ring" Yes NA "Cluster 22: Eosinophils - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 1: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 67 "Nucleoplasm, Nuclear bodies" "Midbody ring" "HPA016812: " "unprognostic (1.59e-1)" "unprognostic (1.43e-2)" "unprognostic (7.78e-3)" "unprognostic (5.18e-2)" "unprognostic (2.62e-2)" "unprognostic (1.77e-1)" "unprognostic (3.43e-1)" "unprognostic (1.22e-3)" "unprognostic (2.74e-2)" "unprognostic (1.24e-1)" "potential prognostic favorable (1.36e-8)" "unprognostic (1.36e-3)" "unprognostic (3.87e-1)" "unprognostic (9.36e-3)" "potential prognostic unfavorable (2.83e-4)" "unprognostic (2.22e-1)" "unprognostic (9.67e-2)" "unprognostic (1.33e-1)" "unprognostic (5.95e-2)" "unprognostic (9.89e-2)" "unprognostic (1.68e-2)" "unprognostic (2.26e-1)" "unprognostic (2.38e-1)" "unprognostic (1.14e-1)" "unprognostic (3.03e-2)" "unprognostic (2.30e-1)" "unprognostic (7.20e-3)" "unprognostic (1.76e-1)" "unprognostic (1.51e-1)" "unprognostic (1.05e-1)" "unprognostic (8.30e-2)" RNF43 "DKFZp781H0392, FLJ20315, URCC" ENSG00000108375 "Ring finger protein 43" Q68DV7 17 58353676-58417595 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Ubl conjugation pathway, Wnt signaling pathway" "Developmental protein, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 21.4" "Cell type enhanced" "Detected in some" "Astrocytes: 38.8;Bergmann glia: 89.7;Brain excitatory neurons: 20.4;Distal convoluted tubule cells: 86.4;Ependymal cells: 165.7;Loop of henle epithelial cells: 70.2;Papillary tip epithelial cells: 54.9;Proximal tubule cells: 27.7;Renal collecting duct intercalated cells: 33.7;Renal collecting duct principal cells: 54.0;Renal connecting tubule cells: 62.3" "Cell type enhanced" "Detected in many" "Bergmann glia: 97.4;ependymal cell: 241.8" "Group enriched" "Detected in many" 4 "Colon Adenocarcinoma (TCGA): 99.8;Rectum Adenocarcinoma (TCGA): 97.8" "Region enhanced" "Detected in all" "cerebellum: 19.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 45.8;colorectal cancer: 71.5" "Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Lung - Alveolar cells type 2, Skin - Keratinocyte (other), Spleen - B-cells (Spleen), Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA008079 Uncertain NA NA "Cluster 77: Intestine - Digestion" "Cluster 2: Neurons - Nucleosome" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 34: Ciliated cells - Cilia assembly & function" 46 "HPA008079: " "unprognostic (6.58e-2)" "unprognostic (1.15e-1)" "unprognostic (1.10e-1)" "unprognostic (1.84e-1)" "unprognostic (1.01e-1)" "unprognostic (1.19e-3)" "unprognostic (1.07e-1)" "unprognostic (8.00e-2)" "validated prognostic favorable (6.02e-5)" "validated prognostic favorable (2.25e-4)" "unprognostic (1.90e-2)" "unprognostic (1.08e-1)" "unprognostic (1.86e-3)" "unprognostic (3.44e-2)" "unprognostic (4.25e-2)" "unprognostic (3.15e-2)" "unprognostic (5.43e-3)" "unprognostic (1.58e-1)" "unprognostic (7.21e-2)" "unprognostic (6.48e-2)" "unprognostic (3.62e-2)" "unprognostic (3.70e-1)" "unprognostic (1.11e-2)" "unprognostic (8.85e-2)" "unprognostic (3.60e-1)" "unprognostic (2.54e-3)" "unprognostic (2.37e-2)" "unprognostic (3.52e-1)" "unprognostic (3.16e-3)" RNF44 KIAA1100 ENSG00000146083 "Ring finger protein 44" Q7L0R7 5 176526712-176538025 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "Late spermatids: 764.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038981 Uncertain Approved Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 9 Nucleoplasm "HPA038981: " "unprognostic (2.08e-1)" "unprognostic (8.92e-2)" "unprognostic (1.01e-1)" "unprognostic (4.73e-2)" "unprognostic (9.83e-2)" "unprognostic (4.21e-1)" "unprognostic (1.62e-1)" "unprognostic (1.25e-1)" "unprognostic (3.56e-2)" "unprognostic (1.74e-1)" "unprognostic (3.50e-2)" "unprognostic (6.91e-2)" "unprognostic (2.31e-1)" "potential prognostic unfavorable (9.92e-5)" "unprognostic (5.93e-2)" "unprognostic (1.11e-1)" "unprognostic (4.37e-1)" "unprognostic (4.49e-2)" "unprognostic (3.26e-2)" "unprognostic (1.64e-2)" "unprognostic (2.84e-1)" "unprognostic (9.84e-2)" "unprognostic (1.80e-3)" "unprognostic (9.19e-2)" "unprognostic (2.24e-2)" "unprognostic (1.89e-1)" "unprognostic (8.55e-2)" "unprognostic (3.68e-2)" "unprognostic (1.35e-1)" "unprognostic (1.50e-3)" "unprognostic (2.05e-1)" RNF5 "G16, NG2, RING5, RMA1" ENSG00000204308 "Ring finger protein 5" Q99942 6 32178405-32180793 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 5.1;Bergmann glia: 8.4;Brain excitatory neurons: 6.8;Brain inhibitory neurons: 5.5;Cholangiocytes: 5.9;Ependymal cells: 8.0;Loop of henle epithelial cells: 8.9;Oligodendrocyte progenitor cells: 6.4;Oligodendrocytes: 13.9;Other brain neurons: 4.9;Papillary tip epithelial cells: 8.8;Podocytes: 5.7;Renal collecting duct intercalated cells: 5.0;Renal collecting duct principal cells: 12.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034107, HPA065032" Uncertain Supported "Endoplasmic reticulum" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 102 "Endoplasmic reticulum" "CAB034107: , HPA065032: " "unprognostic (5.12e-2)" "unprognostic (1.88e-3)" "potential prognostic unfavorable (2.10e-4)" "unprognostic (2.98e-1)" "unprognostic (3.06e-1)" "unprognostic (9.85e-2)" "unprognostic (1.38e-2)" "unprognostic (1.35e-2)" "unprognostic (1.34e-1)" "unprognostic (9.25e-2)" "potential prognostic favorable (1.91e-7)" "unprognostic (4.19e-3)" "unprognostic (6.60e-2)" "unprognostic (1.71e-1)" "unprognostic (1.83e-2)" "unprognostic (1.13e-1)" "unprognostic (1.90e-1)" "unprognostic (8.76e-2)" "unprognostic (4.02e-2)" "unprognostic (1.61e-2)" "unprognostic (9.58e-2)" "unprognostic (1.21e-1)" "unprognostic (2.20e-2)" "unprognostic (6.51e-3)" "unprognostic (8.62e-3)" "unprognostic (3.60e-3)" "unprognostic (3.03e-1)" "unprognostic (1.45e-1)" "unprognostic (1.37e-1)" "unprognostic (2.24e-2)" "unprognostic (2.23e-2)" RNF6 DKFZp686P0776 ENSG00000127870 "Ring finger protein 6" Q9Y252 13 26132115-26222314 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 97.1;Late primary spermatocytes: 163.9;Late spermatids: 238.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039343, HPA040048" Approved Supported "Nuclear membrane" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 12 "Nuclear membrane" "HPA039343: , HPA040048: " "unprognostic (2.71e-1)" "unprognostic (1.83e-1)" "unprognostic (5.18e-1)" "unprognostic (3.63e-3)" "unprognostic (1.29e-1)" "unprognostic (9.19e-2)" "unprognostic (1.20e-1)" "unprognostic (4.25e-3)" "unprognostic (1.49e-1)" "unprognostic (2.41e-2)" "potential prognostic favorable (5.48e-6)" "unprognostic (1.34e-2)" "unprognostic (2.94e-1)" "unprognostic (1.56e-1)" "unprognostic (1.73e-1)" "unprognostic (2.43e-1)" "unprognostic (2.04e-2)" "unprognostic (1.58e-1)" "unprognostic (4.58e-2)" "unprognostic (1.22e-2)" "unprognostic (1.60e-3)" "unprognostic (7.01e-2)" "unprognostic (2.35e-1)" "unprognostic (9.38e-2)" "unprognostic (4.38e-2)" "unprognostic (1.65e-1)" "unprognostic (1.15e-1)" "unprognostic (8.98e-3)" "unprognostic (4.53e-1)" "unprognostic (1.92e-2)" "unprognostic (1.52e-1)" RNF7 "CKBBP1, RBX2, ROC2, SAG" ENSG00000114125 "Ring finger protein 7" Q9UBF6 3 141738249-141747560 "Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 42.5;Late spermatids: 72.5;Papillary tip epithelial cells: 21.0;Tuft cells: 23.1" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036995 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 71 Nucleoplasm Cytosol "HPA036995: " "unprognostic (4.37e-2)" "unprognostic (1.96e-1)" "unprognostic (1.68e-2)" "unprognostic (8.42e-3)" "unprognostic (4.42e-3)" "unprognostic (1.59e-1)" "potential prognostic unfavorable (1.40e-6)" "unprognostic (2.31e-1)" "unprognostic (6.67e-2)" "potential prognostic unfavorable (6.08e-6)" "potential prognostic unfavorable (8.23e-4)" "unprognostic (1.90e-1)" "unprognostic (1.70e-2)" "validated prognostic unfavorable (1.49e-5)" "validated prognostic unfavorable (4.71e-6)" "unprognostic (1.06e-2)" "unprognostic (1.48e-3)" "unprognostic (1.70e-3)" "unprognostic (1.54e-2)" "unprognostic (6.21e-2)" "unprognostic (4.04e-1)" "potential prognostic unfavorable (4.83e-5)" "unprognostic (1.54e-1)" "unprognostic (1.43e-2)" "unprognostic (2.36e-1)" "unprognostic (1.98e-1)" "unprognostic (4.44e-3)" "unprognostic (5.33e-2)" "unprognostic (6.94e-2)" "unprognostic (8.45e-2)" "unprognostic (1.18e-1)" RNF8 KIAA0646 ENSG00000112130 "Ring finger protein 8" O76064 6 37353979-37394734 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Host-virus interaction, Mitosis, Ubl conjugation pathway" "Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA050731, HPA064925" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 1: Neurons - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 91 Nucleoplasm Cytosol "HPA050731: , HPA064925: " "unprognostic (1.75e-1)" "unprognostic (4.55e-2)" "unprognostic (4.01e-2)" "unprognostic (1.21e-1)" "unprognostic (2.42e-1)" "unprognostic (2.90e-1)" "unprognostic (2.11e-2)" "potential prognostic favorable (4.03e-4)" "unprognostic (1.74e-1)" "unprognostic (5.12e-2)" "potential prognostic favorable (5.76e-4)" "unprognostic (2.77e-3)" "unprognostic (6.04e-2)" "validated prognostic unfavorable (1.14e-4)" "validated prognostic unfavorable (1.97e-4)" "unprognostic (8.61e-2)" "unprognostic (2.80e-2)" "unprognostic (8.23e-3)" "unprognostic (2.12e-1)" "unprognostic (2.68e-2)" "unprognostic (1.63e-1)" "unprognostic (1.45e-1)" "unprognostic (1.54e-3)" "unprognostic (1.78e-2)" "unprognostic (1.81e-1)" "unprognostic (1.22e-1)" "unprognostic (5.77e-3)" "unprognostic (2.31e-1)" "unprognostic (5.44e-2)" "unprognostic (1.10e-2)" "unprognostic (3.10e-1)" RNFT1 PTD016 ENSG00000189050 "Ring finger protein, transmembrane 1" Q5M7Z0 17 59952240-59964761 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 60.7" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 180.4;Early spermatids: 242.7;Late primary spermatocytes: 440.2;Late spermatids: 105.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013739 Approved Nucleoli NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 57: Testis - Spermatogenesis" "Cluster 44: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" Nucleoli "HPA013739: " "unprognostic (3.10e-2)" "unprognostic (8.00e-2)" "unprognostic (1.38e-1)" "unprognostic (8.71e-3)" "unprognostic (2.25e-2)" "unprognostic (4.32e-1)" "unprognostic (9.94e-2)" "unprognostic (3.47e-1)" "unprognostic (1.39e-1)" "unprognostic (1.38e-3)" "potential prognostic favorable (2.14e-5)" "unprognostic (2.88e-1)" "unprognostic (1.01e-1)" "unprognostic (1.70e-3)" "unprognostic (5.33e-2)" "unprognostic (1.21e-1)" "unprognostic (1.65e-1)" "unprognostic (1.60e-2)" "unprognostic (1.28e-2)" "unprognostic (7.65e-2)" "unprognostic (7.47e-2)" "unprognostic (1.91e-1)" "unprognostic (4.81e-3)" "unprognostic (4.47e-1)" "unprognostic (3.22e-2)" "unprognostic (1.97e-1)" "unprognostic (5.27e-2)" "unprognostic (1.19e-1)" "unprognostic (4.16e-1)" "unprognostic (1.66e-3)" "unprognostic (2.33e-1)" RNFT2 "FLJ14627, TMEM118" ENSG00000135119 "Ring finger protein, transmembrane 2" Q96EX2 12 116738178-116853631 "Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 10.3;choroid plexus: 4.7;pituitary gland: 4.9;retina: 4.6;testis: 6.5" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 42.5;Corticotrophs: 41.9;Early spermatids: 56.7;Gonadotrophs: 46.2;Lactotrophs: 48.1;Late spermatids: 98.4;Retinal amacrine cells: 50.6;Retinal bipolar cells: 50.4;Retinal ganglion cells: 46.4;Rod photoreceptor cells: 56.2;Somatotrophs: 44.6;Thyrotrophs: 66.6" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 10.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064161 Enhanced Approved Nucleoplasm,Cytosol No No "Cluster 34: B-cells - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 24: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" Nucleoplasm Cytosol "HPA064161: " "unprognostic (2.01e-2)" "unprognostic (2.79e-3)" "unprognostic (3.98e-1)" "unprognostic (1.29e-1)" "unprognostic (1.53e-2)" "unprognostic (2.72e-3)" "unprognostic (1.86e-1)" "unprognostic (3.55e-3)" "unprognostic (1.17e-2)" "unprognostic (6.66e-3)" "unprognostic (1.38e-1)" "unprognostic (7.95e-2)" "unprognostic (2.50e-1)" "unprognostic (1.60e-2)" "unprognostic (2.49e-1)" "unprognostic (1.45e-1)" "unprognostic (1.66e-1)" "unprognostic (7.27e-3)" "unprognostic (1.06e-1)" "unprognostic (2.34e-2)" "unprognostic (9.24e-3)" "unprognostic (2.51e-1)" "unprognostic (2.93e-1)" "unprognostic (1.54e-1)" "potential prognostic favorable (7.35e-4)" RNGTT "hCAP, HCE, HCE1" ENSG00000111880 "RNA guanylyltransferase and 5'-phosphatase" O60942 6 88609897-88963618 "Enzymes, Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, mRNA capping, mRNA processing" "Hydrolase, Multifunctional enzyme, Nucleotidyltransferase, Protein phosphatase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 425.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003750 Approved Approved Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 16: Non-specific - Transcription" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 24 Nucleoplasm "HPA003750: " "unprognostic (6.48e-2)" "unprognostic (1.61e-2)" "unprognostic (1.08e-3)" "unprognostic (1.09e-2)" "unprognostic (8.34e-2)" "unprognostic (4.95e-2)" "unprognostic (9.46e-2)" "unprognostic (2.21e-3)" "unprognostic (4.12e-1)" "unprognostic (1.36e-2)" "potential prognostic favorable (6.33e-5)" "unprognostic (4.29e-3)" "unprognostic (9.87e-2)" "potential prognostic unfavorable (3.33e-4)" "unprognostic (2.09e-3)" "unprognostic (9.60e-3)" "unprognostic (3.33e-2)" "unprognostic (1.23e-2)" "unprognostic (2.89e-1)" "unprognostic (1.56e-1)" "potential prognostic unfavorable (3.77e-4)" "unprognostic (1.63e-1)" "potential prognostic unfavorable (8.96e-5)" "unprognostic (8.89e-2)" "unprognostic (2.89e-2)" "unprognostic (1.56e-2)" "unprognostic (3.23e-1)" "unprognostic (1.61e-1)" "unprognostic (2.64e-1)" "unprognostic (1.04e-1)" "unprognostic (2.10e-1)" RNH1 "RAI, RNH" ENSG00000023191 "Ribonuclease/angiogenin inhibitor 1" P13489 11 494512-507300 "Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 290.8;Esophageal apical cells: 303.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 262.4;monocytes: 300.5" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039223, HPA040781" Enhanced Enhanced Nucleoplasm,Cytosol NA NA 19000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 74: Non-specific - Signal transduction" "Cluster 30: White matter - Myelination" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 33 Cytosol Nucleoplasm "HPA039223: , HPA040781: " "unprognostic (1.99e-2)" "unprognostic (2.51e-1)" "unprognostic (1.46e-1)" "unprognostic (9.72e-2)" "unprognostic (9.88e-2)" "unprognostic (2.10e-1)" "potential prognostic unfavorable (9.74e-4)" "unprognostic (1.97e-2)" "unprognostic (1.19e-1)" "unprognostic (7.70e-2)" "potential prognostic favorable (3.16e-5)" "unprognostic (3.35e-1)" "unprognostic (3.39e-3)" "unprognostic (4.48e-3)" "unprognostic (1.57e-1)" "unprognostic (8.78e-2)" "unprognostic (2.77e-1)" "unprognostic (1.96e-2)" "unprognostic (2.13e-1)" "unprognostic (2.51e-1)" "unprognostic (1.66e-1)" "unprognostic (7.09e-2)" "unprognostic (3.40e-1)" "unprognostic (2.56e-1)" "unprognostic (2.05e-1)" "unprognostic (1.37e-1)" "unprognostic (4.47e-1)" "unprognostic (2.14e-1)" "unprognostic (2.42e-2)" "unprognostic (5.68e-2)" "unprognostic (2.42e-1)" RNLS "C10orf59, FLJ11218, renalase" ENSG00000184719 "Renalase, FAD dependent amine oxidase" Q5VYX0 10 88273864-88584530 "Enzymes, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 258.7;Ependymal cells: 254.4;Myonuclei: 351.9;Thymic myoid cells: 1052.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Stomach - Chief cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" Enzyme NA NA 10500000000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 76: Non-specific - Metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 1 "unprognostic (1.53e-1)" "unprognostic (4.71e-2)" "unprognostic (1.45e-1)" "unprognostic (2.03e-1)" "unprognostic (1.42e-2)" "unprognostic (2.52e-3)" "unprognostic (5.49e-3)" "unprognostic (3.30e-3)" "unprognostic (9.52e-2)" "unprognostic (5.44e-3)" "potential prognostic favorable (1.54e-10)" "unprognostic (3.33e-2)" "unprognostic (1.70e-3)" "unprognostic (1.53e-1)" "unprognostic (2.99e-2)" "unprognostic (5.36e-2)" "unprognostic (1.99e-2)" "unprognostic (1.61e-1)" "unprognostic (7.04e-3)" "unprognostic (8.84e-2)" "unprognostic (4.98e-3)" "unprognostic (7.89e-2)" "unprognostic (5.93e-2)" "unprognostic (5.11e-3)" "unprognostic (3.77e-2)" "unprognostic (2.12e-1)" "unprognostic (3.34e-2)" "unprognostic (2.69e-2)" "unprognostic (1.91e-1)" "unprognostic (1.60e-1)" "unprognostic (6.38e-2)" RNMT "N7-MTase, RG7MT1" ENSG00000101654 "RNA guanine-7 methyltransferase" O43148 18 13726660-13764556 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" "mRNA capping, mRNA processing" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039409 Approved Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 40: Non-specific - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 98: Neurons - Neurotransmission & signaling" 20 Nucleoplasm "Nucleoli fibrillar center" "HPA039409: " "unprognostic (3.54e-1)" "unprognostic (1.22e-1)" "unprognostic (1.06e-1)" "unprognostic (2.97e-2)" "unprognostic (1.24e-1)" "unprognostic (2.07e-1)" "unprognostic (1.54e-1)" "unprognostic (1.57e-2)" "unprognostic (1.38e-1)" "unprognostic (1.43e-2)" "potential prognostic favorable (1.60e-4)" "unprognostic (7.38e-3)" "unprognostic (3.85e-1)" "unprognostic (9.60e-3)" "unprognostic (1.69e-3)" "unprognostic (1.21e-1)" "unprognostic (3.29e-1)" "unprognostic (5.15e-3)" "unprognostic (4.13e-2)" "unprognostic (9.33e-2)" "unprognostic (3.29e-2)" "unprognostic (1.42e-1)" "potential prognostic unfavorable (1.88e-4)" "unprognostic (1.09e-1)" "unprognostic (2.18e-1)" "unprognostic (5.98e-2)" "unprognostic (1.10e-1)" "unprognostic (9.02e-2)" "unprognostic (1.83e-1)" "unprognostic (6.36e-2)" "unprognostic (1.57e-1)" RNPC3 "FLJ20008, KIAA1839, RBM40, SNRNP65" ENSG00000185946 "RNA binding region (RNP1, RRM) containing 3" Q96LT9 1 103525691-103555239 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal convoluted tubule cells: 624.0;Myonuclei: 354.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052434 Supported Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 49: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 56: Non-specific - Sensory perception" "Cluster 7: Non-specific - Transcription" 19 Nucleoplasm "HPA052434: " "unprognostic (2.74e-2)" "unprognostic (1.37e-1)" "unprognostic (1.33e-1)" "unprognostic (3.08e-2)" "unprognostic (2.37e-1)" "unprognostic (7.70e-2)" "unprognostic (7.45e-2)" "unprognostic (6.09e-2)" "unprognostic (7.96e-3)" "unprognostic (1.40e-3)" "unprognostic (4.70e-1)" "unprognostic (2.23e-3)" "unprognostic (1.48e-1)" "unprognostic (5.07e-2)" "unprognostic (9.28e-3)" "unprognostic (1.94e-3)" "unprognostic (7.03e-2)" "unprognostic (2.87e-1)" "unprognostic (9.65e-2)" "unprognostic (3.05e-1)" "unprognostic (3.16e-1)" "unprognostic (7.98e-3)" "unprognostic (1.53e-2)" "unprognostic (3.66e-3)" "potential prognostic favorable (3.18e-4)" "unprognostic (4.38e-2)" "unprognostic (2.68e-1)" "unprognostic (8.25e-3)" "unprognostic (5.12e-2)" "unprognostic (1.13e-1)" "potential prognostic unfavorable (6.70e-4)" RNPEP APB ENSG00000176393 "Arginyl aminopeptidase" Q9H4A4 1 201982372-202006147 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Enterocytes: 207.7;Esophageal apical cells: 200.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 19.8;granulocytes: 23.2;monocytes: 30.0" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Prostate - Prostate basal glandular cells, Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036074, HPA036075, HPA061487" Approved Approved "Golgi apparatus,Principal piece,End piece" "Secreted - unknown location" Enzyme NA NA 6400000 "Cluster 25: Non-specific - Unknown function" "Cluster 17: Intestine - Digestion" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 45: Non-specific - Nuclear processes" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 5 "Golgi apparatus" "Principal piece, End piece" "HPA036074: , HPA036075: , HPA061487: " "unprognostic (7.10e-2)" "unprognostic (1.11e-2)" "unprognostic (3.09e-1)" "unprognostic (1.08e-3)" "unprognostic (2.17e-2)" "unprognostic (4.32e-2)" "unprognostic (3.58e-1)" "unprognostic (2.27e-2)" "unprognostic (3.21e-2)" "unprognostic (1.48e-1)" "potential prognostic favorable (2.26e-6)" "unprognostic (7.34e-2)" "unprognostic (6.20e-2)" "unprognostic (2.18e-1)" "unprognostic (1.27e-2)" "unprognostic (7.07e-3)" "unprognostic (1.62e-1)" "unprognostic (5.91e-3)" "unprognostic (5.90e-2)" "unprognostic (1.02e-2)" "unprognostic (2.92e-1)" "unprognostic (3.00e-2)" "unprognostic (8.67e-2)" "unprognostic (1.66e-1)" "unprognostic (1.90e-2)" "unprognostic (2.78e-2)" "unprognostic (2.34e-3)" "unprognostic (1.27e-1)" "unprognostic (8.69e-2)" "unprognostic (1.34e-2)" "unprognostic (2.37e-1)" RNPEPL1 ENSG00000142327 "Arginyl aminopeptidase like 1" Q9HAU8 2 240565804-240581372 "Enzymes, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Colonocytes: 107.9;Esophageal apical cells: 168.8;Foveolar cells: 121.7;Megakaryocytes: 160.7" "Cell type enhanced" "Detected in all" "leukocyte: 56.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036772, HPA036773" Uncertain Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 35: RS4;11 - Unknown function" "Cluster 47: Platelets - Hemostasis" 1 Nucleoplasm "Nuclear bodies" "HPA036772: , HPA036773: " "potential prognostic favorable (5.46e-4)" "unprognostic (8.12e-3)" "unprognostic (8.39e-3)" "unprognostic (3.42e-1)" "unprognostic (6.10e-2)" "unprognostic (2.36e-1)" "unprognostic (1.83e-2)" "unprognostic (1.12e-1)" "unprognostic (1.26e-2)" "unprognostic (3.26e-2)" "potential prognostic unfavorable (8.13e-5)" "unprognostic (6.99e-3)" "potential prognostic favorable (6.09e-4)" "potential prognostic unfavorable (3.14e-4)" "unprognostic (2.82e-2)" "unprognostic (4.91e-2)" "unprognostic (1.34e-1)" "unprognostic (4.12e-2)" "unprognostic (2.78e-1)" "unprognostic (1.76e-1)" "unprognostic (4.28e-3)" "unprognostic (3.70e-1)" "unprognostic (1.29e-1)" "unprognostic (9.84e-2)" "unprognostic (1.61e-3)" "unprognostic (3.96e-1)" "unprognostic (2.06e-1)" "unprognostic (1.62e-1)" "unprognostic (1.60e-1)" "unprognostic (6.86e-2)" "unprognostic (1.46e-1)" RNPS1 ENSG00000205937 "RNA binding protein with serine rich domain 1" Q15287 16 2253116-2268397 "Essential proteins, Predicted intracellular proteins, Transporters" "mRNA processing, mRNA splicing, Nonsense-mediated mRNA decay" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044014 Approved Supported Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 24: Non-specific - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 54: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 221 Nucleoplasm "HPA044014: " "unprognostic (6.32e-2)" "unprognostic (6.90e-3)" "unprognostic (4.78e-2)" "unprognostic (5.22e-2)" "unprognostic (3.21e-1)" "unprognostic (1.88e-1)" "unprognostic (2.78e-1)" "unprognostic (3.65e-3)" "unprognostic (2.90e-1)" "unprognostic (2.45e-1)" "unprognostic (1.87e-1)" "unprognostic (2.33e-1)" "unprognostic (1.96e-1)" "validated prognostic unfavorable (9.14e-4)" "validated prognostic unfavorable (2.53e-4)" "unprognostic (4.36e-3)" "unprognostic (2.78e-2)" "unprognostic (3.56e-1)" "unprognostic (1.78e-2)" "unprognostic (1.95e-1)" "unprognostic (3.61e-1)" "unprognostic (1.58e-1)" "unprognostic (2.23e-2)" "unprognostic (5.75e-3)" "unprognostic (6.69e-2)" "unprognostic (1.79e-1)" "unprognostic (1.18e-1)" "unprognostic (1.03e-1)" "unprognostic (8.41e-2)" "unprognostic (6.78e-3)" "unprognostic (4.53e-1)" RO60 "SSA2, TROVE2" ENSG00000116747 "Ro60, Y RNA binding protein" P10155 1 193059454-193091777 "Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 462.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002835 Uncertain Approved "Nucleoplasm,Nuclear bodies,Primary cilium,Cytosol" NA NA 65000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 40: Non-specific - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 16 "Primary cilium, Cytosol" "Nucleoplasm, Nuclear bodies" "HPA002835: " "unprognostic (3.65e-2)" "unprognostic (2.07e-2)" "potential prognostic unfavorable (4.25e-4)" "unprognostic (1.62e-1)" "unprognostic (1.18e-1)" "unprognostic (4.06e-2)" "unprognostic (4.45e-1)" "unprognostic (2.31e-1)" "unprognostic (7.24e-3)" "potential prognostic favorable (4.27e-5)" "unprognostic (2.68e-2)" "unprognostic (7.72e-2)" "unprognostic (1.00e-2)" "unprognostic (1.36e-1)" "unprognostic (9.40e-2)" "unprognostic (1.63e-1)" "unprognostic (3.17e-1)" "unprognostic (2.61e-1)" "potential prognostic unfavorable (3.81e-5)" "unprognostic (1.50e-2)" "unprognostic (1.94e-1)" "unprognostic (3.70e-2)" "unprognostic (1.19e-1)" "unprognostic (1.36e-1)" "unprognostic (1.39e-1)" "unprognostic (5.70e-2)" "unprognostic (1.59e-1)" "potential prognostic unfavorable (1.20e-4)" "unprognostic (1.11e-1)" ROBO1 "DUTT1, FLJ21882, SAX3" ENSG00000169855 "Roundabout guidance receptor 1" Q9Y6N7 3 78597239-79767998 "Predicted intracellular proteins, Predicted membrane proteins" "Chemotaxis, Differentiation, Neurogenesis" "Developmental protein, Receptor" "Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 1648.7;Brain excitatory neurons: 1017.0;Brain inhibitory neurons: 2256.4;Lactotrophs: 5760.6;Other brain neurons: 1644.2;Prostatic club cells: 945.3;Thyrotrophs: 1197.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Fibroblasts, Prostate - Urothelial cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013524, HPA052968, HPA074461" Uncertain Supported "Plasma membrane,Primary cilium" NA NA 7300000 "Cluster 61: Non-specific - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 6 "Plasma membrane" "Primary cilium" "CAB013524: , HPA052968: , HPA074461: " "unprognostic (2.83e-1)" "unprognostic (4.14e-1)" "unprognostic (4.24e-2)" "unprognostic (1.22e-2)" "unprognostic (1.41e-1)" "unprognostic (2.65e-2)" "unprognostic (4.46e-1)" "unprognostic (2.89e-1)" "potential prognostic favorable (1.50e-4)" "unprognostic (5.29e-2)" "potential prognostic favorable (5.71e-5)" "unprognostic (2.26e-1)" "unprognostic (1.57e-1)" "potential prognostic unfavorable (5.19e-4)" "unprognostic (9.62e-2)" "unprognostic (3.60e-1)" "unprognostic (1.59e-1)" "unprognostic (9.87e-2)" "unprognostic (2.94e-1)" "unprognostic (1.36e-1)" "unprognostic (1.79e-1)" "unprognostic (8.14e-2)" "unprognostic (1.60e-1)" "unprognostic (1.12e-1)" "unprognostic (1.12e-2)" "potential prognostic favorable (7.36e-4)" "unprognostic (8.65e-2)" "unprognostic (1.48e-2)" "unprognostic (1.89e-1)" "unprognostic (1.95e-2)" "unprognostic (2.36e-1)" ROBO2 KIAA1568 ENSG00000185008 "Roundabout guidance receptor 2" Q9HCK4 3 75906695-77649964 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Chemotaxis, Differentiation, Neurogenesis" "Developmental protein, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.4;ovary: 13.1" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 1735.5;Brain inhibitory neurons: 3594.0;Ependymal cells: 1137.8;Fibro-adipogenic progenitors: 997.8;Lactotrophs: 1602.3;Other brain neurons: 1567.7;Podocytes: 917.5;Retinal bipolar cells: 2300.0;Retinal ganglion cells: 3970.9;Sertoli cells: 758.3;Somatotrophs: 1964.4" "Cell type enhanced" "Detected in all" "lower rhombic lip: 8990.0" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 20.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Adrenal medulla cells, Kidney - Podocytes, Lung - Fibroblasts_1, Pancreas - Beta cells, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013371, HPA014209" Approved Approved "Vesicles,Plasma membrane" NA NA 810000 "Cluster 65: Brain - Transcription" "Cluster 24: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 109: Neurons - Neuronal signaling" 1 "Vesicles, Plasma membrane" "HPA013371: , HPA014209: " "unprognostic (3.59e-2)" "unprognostic (3.01e-3)" "unprognostic (3.52e-1)" "unprognostic (2.95e-2)" "unprognostic (9.60e-3)" "unprognostic (1.30e-1)" "unprognostic (7.55e-3)" "unprognostic (4.31e-2)" "unprognostic (2.35e-2)" "unprognostic (3.19e-1)" "potential prognostic favorable (1.86e-5)" "unprognostic (1.49e-2)" "unprognostic (1.06e-2)" "unprognostic (6.81e-2)" "unprognostic (7.56e-2)" "unprognostic (3.27e-2)" "unprognostic (2.80e-1)" "unprognostic (3.75e-1)" "unprognostic (2.31e-1)" "unprognostic (8.81e-2)" "unprognostic (2.89e-2)" "unprognostic (1.99e-1)" "unprognostic (2.19e-2)" "unprognostic (1.52e-1)" "unprognostic (9.47e-2)" "unprognostic (4.46e-1)" ROBO3 "FLJ21044, HGPPS, HGPS, RBIG1" ENSG00000154134 "Roundabout guidance receptor 3" Q96MS0 11 124865432-124881471 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Chemotaxis, Differentiation, Neurogenesis" "Developmental protein, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 8.7" "Cell type enhanced" "Detected in many" "Astrocytes: 59.9;Bergmann glia: 117.8;Epididymal efferent duct absorptive cells: 40.1;Fibro-adipogenic progenitors: 28.0;Granulosa cells: 35.7;Lymphatic endothelial cells: 33.6;Mesothelial cells: 47.4;Müller glia: 42.9;Oocytes: 32.2;Ovarian stromal cells: 28.6" "Cell type enhanced" "Detected in many" "astrocyte: 65.4;Bergmann glia: 108.8;deep-layer near-projecting: 61.6" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 3.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Mesothelial cells, Colon - Enteric glia cells, Thyroid gland - Fibroblasts" "Region enhanced" "Detected in single" "cerebral cortex: 2.1" "Low region specificity" "Detected in many" HPA071053 Approved "Vesicles,Plasma membrane" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 1: Neuronal - Visual perception" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "Plasma membrane" Vesicles "HPA071053: " "unprognostic (3.21e-1)" "unprognostic (1.41e-1)" "unprognostic (1.97e-1)" "unprognostic (1.76e-1)" "unprognostic (3.36e-1)" "unprognostic (4.45e-3)" "unprognostic (2.14e-2)" "unprognostic (3.39e-3)" "unprognostic (2.23e-2)" "unprognostic (2.74e-1)" "unprognostic (1.32e-1)" ROBO4 "ECSM4, FLJ20798, MRB" ENSG00000154133 "Roundabout guidance receptor 4" Q8WZ75 11 124883691-124898500 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Differentiation" "Developmental protein, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 6 "Hematopoietic stem cells: 36.4;Lymphatic endothelial cells: 131.5;Vascular endothelial cells: 131.4" "Cell type enriched" "Detected in some" 6 "endothelial cell: 175.1" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 33.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Sarcoma: 3.7" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Lung - Endothelial cells, Minor Salivary Gland - Endothelial cells, Pancreas - Endothelial cells, Pituitary gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Spleen - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065212 Approved "Plasma membrane" NA NA 33000000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 1 "Plasma membrane" "HPA065212: " "unprognostic (1.69e-1)" "unprognostic (1.25e-1)" "unprognostic (2.68e-2)" "unprognostic (1.79e-2)" "unprognostic (1.27e-1)" "unprognostic (9.74e-2)" "unprognostic (3.88e-2)" "unprognostic (1.18e-1)" "unprognostic (6.47e-2)" "unprognostic (2.26e-2)" "validated prognostic favorable (3.30e-8)" "validated prognostic favorable (1.28e-4)" "unprognostic (1.74e-2)" "unprognostic (1.19e-3)" "potential prognostic favorable (8.43e-5)" "unprognostic (3.85e-1)" "unprognostic (2.13e-1)" "unprognostic (3.63e-3)" "unprognostic (1.66e-1)" "unprognostic (8.63e-2)" "unprognostic (1.30e-1)" "unprognostic (5.14e-3)" "unprognostic (5.72e-2)" "unprognostic (1.26e-1)" "unprognostic (3.21e-2)" "unprognostic (2.92e-2)" "unprognostic (1.47e-1)" "unprognostic (6.86e-3)" "unprognostic (1.87e-1)" "unprognostic (3.72e-1)" "unprognostic (8.21e-3)" ROCK1 p160ROCK ENSG00000067900 "Rho associated coiled-coil containing protein kinase 1" Q13464 18 20946906-21111813 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 966.9;Neutrophils: 1713.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004562, HPA007567, HPA045639" Approved NA NA 41000 "Cluster 35: Neutrophils - Protein binding" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 25: Non-specific - Transcription" "Cluster 13: Non-specific - Mixed function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 33 "CAB004562: , HPA007567: , HPA045639: " "unprognostic (4.11e-2)" "unprognostic (2.17e-1)" "unprognostic (9.76e-2)" "unprognostic (2.55e-2)" "unprognostic (4.10e-1)" "unprognostic (2.55e-1)" "unprognostic (4.06e-1)" "unprognostic (1.10e-1)" "unprognostic (6.51e-3)" "unprognostic (1.47e-2)" "unprognostic (3.14e-3)" "unprognostic (7.39e-3)" "unprognostic (1.81e-1)" "unprognostic (9.38e-2)" "unprognostic (3.76e-2)" "unprognostic (2.64e-1)" "unprognostic (2.43e-1)" "unprognostic (1.27e-1)" "unprognostic (1.48e-1)" "unprognostic (1.68e-1)" "unprognostic (3.97e-2)" "unprognostic (7.53e-2)" "unprognostic (2.50e-2)" "unprognostic (5.24e-2)" "unprognostic (5.24e-2)" "unprognostic (1.30e-1)" "unprognostic (3.98e-1)" "unprognostic (8.79e-3)" "unprognostic (3.71e-1)" "unprognostic (1.09e-1)" "unprognostic (1.64e-1)" ROCK2 ENSG00000134318 "Rho associated coiled-coil containing protein kinase 2" O75116 2 11179759-11348330 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast), Prostate - Smooth muscle cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007459, CAB008666, HPA044109" Approved Supported Cytosol NA NA 400000 "Cluster 75: Ovary - Mixed function" "Cluster 34: Non-specific - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 110: Mural cells - ECM organization" 36 Cytosol "CAB008666: , HPA007459: , HPA044109: " "unprognostic (1.70e-2)" "unprognostic (4.46e-2)" "unprognostic (2.36e-1)" "unprognostic (7.07e-2)" "unprognostic (7.87e-2)" "unprognostic (7.06e-3)" "unprognostic (3.92e-1)" "unprognostic (5.23e-2)" "unprognostic (3.66e-1)" "unprognostic (1.90e-2)" "potential prognostic favorable (6.61e-5)" "unprognostic (3.13e-3)" "unprognostic (4.86e-3)" "unprognostic (1.11e-2)" "unprognostic (3.05e-1)" "unprognostic (1.85e-1)" "unprognostic (7.57e-2)" "unprognostic (5.22e-2)" "unprognostic (1.22e-1)" "unprognostic (8.46e-2)" "unprognostic (2.14e-2)" "unprognostic (5.15e-2)" "unprognostic (3.01e-2)" "unprognostic (2.10e-1)" "unprognostic (4.43e-2)" "unprognostic (9.59e-2)" "unprognostic (4.51e-2)" "unprognostic (1.11e-1)" "unprognostic (3.44e-1)" "unprognostic (1.90e-2)" "unprognostic (3.08e-2)" ROGDI "FLJ22386, RAV2, ROGD1" ENSG00000067836 "Rogdi atypical leucine zipper" Q9GZN7 16 4796968-4802880 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Amelogenesis imperfecta, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 20.7;Bergmann glia: 13.9;Brain excitatory neurons: 44.3;Brain inhibitory neurons: 32.9;Choroid plexus epithelial cells: 16.2;Ependymal cells: 18.1;Microglia: 12.6;Oligodendrocyte progenitor cells: 13.2;Oligodendrocytes: 94.9;Other brain neurons: 30.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "classical monocyte: 74.8;intermediate monocyte: 62.8;myeloid DC: 61.6;non-classical monocyte: 62.1;plasmacytoid DC: 34.6" "Group enriched" "Detected in all" 6 "dendritic cells: 61.6;monocytes: 74.8" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041000 Uncertain NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 52: Non-specific - Cellular respiration" "Cluster 51: Neurons - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" 9 "HPA041000: " "unprognostic (9.52e-3)" "unprognostic (7.40e-2)" "unprognostic (1.19e-1)" "unprognostic (5.59e-3)" "unprognostic (1.58e-1)" "unprognostic (1.25e-1)" "unprognostic (1.30e-2)" "unprognostic (1.48e-2)" "unprognostic (2.08e-1)" "potential prognostic favorable (1.95e-4)" "unprognostic (2.62e-3)" "unprognostic (3.53e-2)" "unprognostic (5.45e-3)" "unprognostic (1.64e-1)" "unprognostic (1.23e-1)" "unprognostic (1.41e-2)" "unprognostic (5.94e-1)" "unprognostic (1.18e-1)" "unprognostic (1.56e-1)" "unprognostic (2.67e-1)" "unprognostic (7.34e-2)" "unprognostic (2.15e-3)" "unprognostic (2.51e-1)" "unprognostic (4.95e-2)" "unprognostic (2.38e-1)" "unprognostic (1.99e-1)" "unprognostic (2.14e-2)" "unprognostic (1.22e-2)" "unprognostic (8.40e-2)" "unprognostic (6.17e-1)" "unprognostic (1.79e-1)" ROM1 "ROM, TSPAN23" ENSG00000149489 "Retinal outer segment membrane protein 1" Q03395 11 62611722-62615116 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Sensory transduction, Vision" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 16 "retina: 1101.4" "Cell type enriched" "Detected in many" 8 "Rod photoreceptor cells: 1647.4" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in all" 5 "Glioblastoma Multiforme (TCGA): 51.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 2.7" "Group enriched" "Detected in many" 4 "NK-cells: 2.7;T-cells: 1.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028910, HPA073279" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" No No "Cluster 24: Non-specific - Transcription" "Cluster 42: Retina - Visual perception" "Cluster 19: Astrocytes - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 79: Photoreceptor cells - Phototransduction" 4 "Plasma membrane, Cytosol" Nucleoplasm "HPA028910: , HPA073279: " "unprognostic (1.34e-1)" "unprognostic (3.25e-2)" "potential prognostic favorable (4.15e-4)" "unprognostic (8.66e-2)" "unprognostic (2.49e-2)" "unprognostic (1.37e-1)" "unprognostic (3.68e-2)" "unprognostic (3.73e-2)" "unprognostic (3.64e-1)" "unprognostic (2.51e-2)" "potential prognostic unfavorable (1.54e-4)" "unprognostic (1.03e-1)" "unprognostic (6.58e-3)" "unprognostic (2.84e-1)" "unprognostic (1.99e-2)" "potential prognostic favorable (8.75e-4)" "unprognostic (4.18e-2)" "unprognostic (3.42e-2)" "unprognostic (2.36e-1)" "unprognostic (3.12e-1)" "unprognostic (3.17e-1)" "unprognostic (3.19e-2)" "unprognostic (3.20e-2)" "unprognostic (5.46e-2)" "unprognostic (5.50e-2)" "unprognostic (4.31e-2)" "unprognostic (6.46e-2)" "unprognostic (2.12e-1)" "unprognostic (2.74e-1)" "unprognostic (2.54e-1)" "unprognostic (9.48e-2)" ROMO1 "bA353C18.2, C20orf52, MTGMP" ENSG00000125995 "Reactive oxygen species modulator 1" P60602 20 35699272-35700984 "Essential proteins, Predicted intracellular proteins, Transporters" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 621.2;Esophageal apical cells: 944.4;Hepatocytes: 707.7;Parietal cells: 760.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012782 Uncertain NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 62: Non-specific - Plasma proteins" "Cluster 97: Non-specific - Cellular respiration" 1 "HPA012782: " "unprognostic (6.37e-2)" "unprognostic (2.90e-1)" "unprognostic (3.35e-1)" "potential prognostic favorable (1.29e-4)" "unprognostic (1.76e-1)" "unprognostic (2.79e-1)" "unprognostic (6.07e-2)" "unprognostic (3.61e-1)" "unprognostic (1.31e-3)" "unprognostic (7.78e-3)" "unprognostic (1.51e-3)" "unprognostic (1.48e-3)" "unprognostic (4.91e-2)" "unprognostic (1.18e-2)" "potential prognostic unfavorable (2.83e-8)" "unprognostic (3.18e-2)" "unprognostic (9.12e-2)" "unprognostic (2.67e-1)" "unprognostic (4.30e-1)" "unprognostic (3.02e-1)" "unprognostic (2.64e-1)" "unprognostic (6.89e-2)" "unprognostic (7.28e-2)" "unprognostic (1.84e-1)" "unprognostic (3.14e-2)" "unprognostic (2.76e-2)" "unprognostic (9.93e-2)" "unprognostic (3.74e-2)" "unprognostic (2.03e-1)" "unprognostic (1.74e-1)" "unprognostic (8.00e-2)" ROPN1 "CT91, ODF6, ROPN1A, ropporin" ENSG00000065371 "Rhophilin associated tail protein 1" Q9HAT0 3 123968521-123992178 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 151.3" "Group enriched" "Detected in some" 16 "Early spermatids: 1412.0;Late primary spermatocytes: 1383.0;Late spermatids: 705.7" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Skin Cutaneous Melanoma (TCGA): 26.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 9 "skin cancer: 20.2" "Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Corticotropes, Testis - Early spermatids, Testis - Late spermatids" HPA052530 Supported Approved "Principal piece" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 9: Non-specific - Receptor signaling" "Cluster 69: Skin cancer - ECM organization" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 38 "Principal piece" "HPA052530: " "potential prognostic favorable (3.19e-4)" "unprognostic (1.74e-1)" "unprognostic (1.00e-1)" ROPN1B ENSG00000114547 "Rhophilin associated tail protein 1B" Q9BZX4 3 125969160-125983454 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 204.8" "Group enriched" "Detected in many" 13 "Early spermatids: 2018.9;Late primary spermatocytes: 1856.8;Late spermatids: 2378.1" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in some" 4 "Skin Cutaneous Melanoma (TCGA): 41.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "skin cancer: 29.4" "Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Skin - Eccrine sweat gland cells, Testis - Early spermatids, Testis - Late spermatids" HPA052530 Supported Approved "Principal piece" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 9: Non-specific - Receptor signaling" "Cluster 69: Skin cancer - ECM organization" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 1 "Principal piece" "HPA052530: " "potential prognostic favorable (4.98e-4)" "unprognostic (2.18e-1)" "potential prognostic favorable (8.33e-4)" "unprognostic (2.05e-1)" "unprognostic (6.87e-2)" "unprognostic (2.60e-1)" "unprognostic (3.62e-1)" "unprognostic (8.70e-2)" ROPN1L "ASP, FLJ25776, RSPH11" ENSG00000145491 "Rhophilin associated tail protein 1 like" Q96C74 5 10441524-10472029 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "testis: 304.2" "Group enriched" "Detected in many" 5 "Early spermatids: 2979.4;Late primary spermatocytes: 3415.0;Late spermatids: 4288.1" "Cell type enriched" "Detected in many" 13 "ependymal cell: 359.6" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 13.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 12 "basophil: 45.2;eosinophil: 55.2;neutrophil: 105.7" "Lineage enriched" "Detected in many" 18 "granulocytes: 105.7" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells, Spleen - Neutrophils_2, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039193, HPA041830" Enhanced Supported "Nucleoplasm,Vesicles,Primary cilium transition zone,Mid piece,Principal piece,End piece" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 79: Testis - Spermatogenesis" "Cluster 17: Choroid plexus - Cilium" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 6 "Primary cilium transition zone, Mid piece, Principal piece, End piece" "Nucleoplasm, Vesicles" "HPA039193: , HPA041830: " "potential prognostic favorable (2.74e-4)" "unprognostic (3.32e-1)" "unprognostic (7.34e-3)" "unprognostic (1.13e-1)" "unprognostic (7.73e-2)" "unprognostic (1.18e-1)" "unprognostic (5.54e-2)" "unprognostic (5.81e-2)" "unprognostic (9.42e-2)" "unprognostic (1.86e-2)" "unprognostic (1.19e-1)" "unprognostic (2.10e-2)" "unprognostic (4.87e-2)" "unprognostic (2.56e-1)" "unprognostic (4.42e-2)" ROR1 NTRKR1 ENSG00000185483 "Receptor tyrosine kinase like orphan receptor 1" Q01973 1 63774017-64181498 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Wnt signaling pathway" "Kinase, Receptor, Transferase" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 23.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 1246.5;Cardiomyocytes: 921.4;Choroid plexus epithelial cells: 777.9;Epicardial cells: 591.3;Mesothelial cells: 563.7;Mucous neck cells: 630.5;Pituitary stem cells: 512.4;Respiratory ionocytes: 350.5" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 587.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatic stellate cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Intracellular and membrane" Receptor NA NA 1000000 "Cluster 69: Parathyroid gland - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 11 "unprognostic (1.68e-2)" "unprognostic (2.17e-1)" "unprognostic (2.15e-1)" "unprognostic (1.55e-1)" "unprognostic (2.05e-1)" "unprognostic (1.85e-3)" "unprognostic (1.23e-3)" "potential prognostic favorable (8.09e-7)" "unprognostic (7.77e-2)" "unprognostic (9.46e-2)" "unprognostic (1.81e-1)" "unprognostic (2.03e-1)" "unprognostic (1.21e-2)" "unprognostic (1.67e-1)" "unprognostic (1.70e-1)" "unprognostic (2.44e-2)" "unprognostic (8.36e-2)" "unprognostic (2.60e-2)" "unprognostic (3.55e-2)" "unprognostic (1.24e-1)" "unprognostic (2.03e-1)" "unprognostic (1.79e-2)" "unprognostic (5.39e-2)" "unprognostic (8.92e-2)" "unprognostic (4.78e-2)" ROR2 "BDB, BDB1, NTRKR2" ENSG00000169071 "Receptor tyrosine kinase like orphan receptor 2" Q01974 9 91563091-91950228 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 188.5;Choroid plexus epithelial cells: 1200.7;Decidual stromal cells: 300.6;Endometrial stromal cells: 291.7;Ependymal cells: 229.3;Epicardial cells: 400.2;Mesothelial cells: 472.4;Prostatic glandular cells: 216.1;Retinal pigment epithelial cells: 225.9;Smooth muscle cells: 252.6" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 1012.0;ependymal cell: 257.2" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 13 "choroid plexus: 58.3" "Immune cell enriched" "Detected in single" 6 "MAIT T-cell: 1.0" "Lineage enriched" "Detected in single" 6 "T-cells: 1.0" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 7 "cerebellum: 9.5;spinal cord: 4.8" NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 20: Myeloma - Immune response" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 65 "unprognostic (8.17e-2)" "unprognostic (3.24e-3)" "unprognostic (5.81e-2)" "unprognostic (3.56e-1)" "unprognostic (5.46e-2)" "unprognostic (1.72e-2)" "unprognostic (4.45e-2)" "unprognostic (1.50e-2)" "unprognostic (2.35e-1)" "unprognostic (1.40e-1)" "unprognostic (1.28e-3)" "unprognostic (7.28e-3)" "unprognostic (2.90e-2)" "unprognostic (1.40e-2)" "unprognostic (7.15e-3)" "unprognostic (2.26e-2)" "unprognostic (1.94e-1)" "unprognostic (2.32e-1)" "unprognostic (5.64e-2)" "unprognostic (2.96e-2)" "unprognostic (9.74e-2)" "unprognostic (3.57e-2)" "unprognostic (3.02e-1)" "unprognostic (5.37e-2)" "unprognostic (2.44e-1)" "unprognostic (1.29e-1)" "unprognostic (2.76e-3)" "unprognostic (6.24e-2)" "potential prognostic unfavorable (1.16e-6)" "unprognostic (1.83e-2)" RORA "NR1F1, ROR1, ROR2, ROR3, RZRA" ENSG00000069667 "RAR related orphan receptor A" P35398 15 60488284-61229302 "Disease related genes, Human disease related genes, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Receptor" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 77.7" "Cell type enhanced" "Detected in many" "Astrocytes: 3789.4;Fibro-adipogenic progenitors: 3857.9;Lactotrophs: 3076.8;Myonuclei: 3994.2;Pituitary stem cells: 3508.1;Retinal bipolar cells: 5473.1;Thyrotrophs: 3332.1" "Cell type enhanced" "Detected in all" "cerebellar inhibitory: 11925.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Lineage enriched" "Detected in many" 4 "T-cells: 26.7" "Cancer enhanced" "Detected in many" "Myeloma: 25.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009861, HPA074448" Approved Supported Nucleoli NA NA "Cluster 1: T-cells - Unknown function" "Cluster 37: Skin - Keratinization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 20: Myeloma - Immune response" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 13 Nucleoli "CAB009861: , HPA074448: " "unprognostic (7.67e-2)" "unprognostic (2.16e-2)" "unprognostic (9.23e-3)" "unprognostic (2.45e-1)" "unprognostic (1.00e-1)" "unprognostic (1.11e-1)" "unprognostic (5.18e-2)" "unprognostic (3.89e-2)" "unprognostic (2.82e-1)" "unprognostic (1.12e-1)" "validated prognostic favorable (2.45e-9)" "validated prognostic favorable (1.69e-5)" "unprognostic (8.25e-3)" "unprognostic (7.33e-3)" "potential prognostic favorable (7.60e-4)" "unprognostic (1.67e-2)" "unprognostic (9.11e-3)" "unprognostic (1.73e-1)" "unprognostic (1.92e-1)" "unprognostic (2.24e-2)" "unprognostic (2.14e-1)" "unprognostic (5.26e-2)" "unprognostic (2.23e-2)" "unprognostic (2.38e-2)" "unprognostic (3.89e-1)" "unprognostic (1.08e-3)" "unprognostic (3.15e-2)" "unprognostic (1.07e-1)" "unprognostic (2.97e-1)" "unprognostic (4.13e-2)" "unprognostic (1.35e-1)" RORB "NR1F2, ROR-BETA, RZRB" ENSG00000198963 "RAR related orphan receptor B" Q92753 9 74497335-74693177 "Disease related genes, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Sensory transduction, Transcription, Transcription regulation, Vision" "Activator, Developmental protein, DNA-binding, Receptor" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "retina: 51.5" "Cell type enhanced" "Detected in many" "Astrocytes: 481.7;Cone photoreceptor cells: 275.3;Corticotrophs: 680.7;Decidual stromal cells: 507.6;Endometrial stromal cells: 1493.9;Müller glia: 736.2;Retinal amacrine cells: 335.1;Retinal horizontal cells: 1869.2;Retinal pigment epithelial cells: 686.3;Rod photoreceptor cells: 297.6" "Group enriched" "Detected in many" 6 "astrocyte: 417.3;Bergmann glia: 204.4;deep-layer intratelencephalic: 317.9;midbrain-derived inhibitory: 722.3;thalamic excitatory: 191.1;upper-layer intratelencephalic: 226.0" "Group enriched" "Detected in some" 4 "Glioblastoma Multiforme (TCGA): 3.3;Prostate Adenocarcinoma (TCGA): 3.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 6.9" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008393 Uncertain Approved Nucleoplasm NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 108: Fibroblasts - ECM organization" 4 Nucleoplasm "HPA008393: " "unprognostic (4.88e-1)" "unprognostic (2.89e-1)" "unprognostic (1.03e-1)" "unprognostic (1.02e-1)" RORC "NR1F3, RORG, RZRG, TOR" ENSG00000143365 "RAR related orphan receptor C" P51449 1 151806071-151831845 "Disease related genes, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 100.2" "Cell type enhanced" "Detected in many" "Breast lactating cells: 110.5;Enterocytes: 44.5;Hepatocytes: 65.9;Innate lymphoid cells: 52.6;Myonuclei: 75.7;Tuft cells: 57.6" "Group enriched" "Detected in some" 4 "choroid plexus epithelial cell: 14.8;ependymal cell: 21.7" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "cerebellum: 4.3;choroid plexus: 8.4;midbrain: 2.5" "Immune cell enriched" "Detected in many" 6 "MAIT T-cell: 50.2" "Lineage enriched" "Detected in many" 44 "T-cells: 50.2" "Cancer enhanced" "Detected in many" "breast cancer: 4.8;prostate cancer: 4.8" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA065620 Supported "Nuclear bodies" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 6 "Nuclear bodies" "HPA065620: " "unprognostic (1.77e-1)" "unprognostic (2.11e-1)" "unprognostic (1.35e-2)" "unprognostic (2.89e-2)" "unprognostic (1.28e-3)" "unprognostic (1.61e-1)" "potential prognostic favorable (5.45e-5)" "unprognostic (1.12e-1)" "validated prognostic favorable (5.87e-10)" "validated prognostic favorable (1.11e-4)" "unprognostic (4.43e-1)" "validated prognostic favorable (5.87e-4)" "validated prognostic favorable (4.16e-4)" "unprognostic (2.56e-2)" "unprognostic (2.01e-1)" "unprognostic (5.30e-3)" "unprognostic (1.06e-1)" "unprognostic (2.43e-1)" "unprognostic (8.20e-2)" "unprognostic (1.97e-1)" "unprognostic (8.51e-3)" "unprognostic (1.13e-1)" "unprognostic (1.15e-1)" "unprognostic (7.25e-3)" "unprognostic (2.77e-1)" "unprognostic (1.37e-1)" "unprognostic (2.86e-1)" "unprognostic (1.94e-1)" "unprognostic (4.60e-2)" ROS1 "c-ros-1, MCF3, ROS" ENSG00000047936 "ROS proto-oncogene 1, receptor tyrosine kinase" P08922 6 117287353-117425942 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 20 "epididymis: 55.3;lung: 29.9" "Group enriched" "Detected in some" 4 "Alveolar cells type 2: 154.0;Transitional alveolar cells: 77.9" "Group enriched" "Detected in some" 4 "deep-layer corticothalamic and 6b: 2.9;upper-layer intratelencephalic: 2.3" "Cancer enriched" "Detected in some" 4 "Lung Adenocarcinoma (TCGA): 24.7" "Region enhanced" "Detected in some" "cerebral cortex: 7.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 5.6;Bone cancer: 8.7;Brain cancer: 5.6" "Lung - Alveolar cells type 2, Skin - Sebaceous gland cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049098, HPA072424" Uncertain Approved Vesicles NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 81: Alveolar cells - Lung function" 12 Vesicles "HPA049098: , HPA072424: " "unprognostic (4.47e-2)" "unprognostic (2.50e-2)" "unprognostic (8.43e-3)" "unprognostic (1.14e-1)" "unprognostic (6.10e-2)" "unprognostic (3.11e-1)" "unprognostic (5.94e-3)" "unprognostic (1.48e-1)" "unprognostic (1.12e-1)" "unprognostic (5.21e-2)" RP1 "DCDC4A, ORP1" ENSG00000104237 "RP1 axonemal microtubule associated" P56715 8 54509422-54871720 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Sensory transduction, Vision" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "retina: 218.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 211.2;Endometrial ciliated cells: 658.9;Fallopian tube ciliated cells: 586.5;Loop of henle epithelial cells: 330.2;Respiratory ciliated cells: 2984.6;Rod photoreceptor cells: 946.4;Transitional alveolar cells: 340.5" "Group enriched" "Detected in some" 9 "endothelial cell: 88.0;ependymal cell: 31.6" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 1.6" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Adipocytes (Visceral), Lung - Respiratory ciliated cells, Stomach - Parietal cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Region enhanced" "Detected in single" "midbrain: 2.9" "HPA027253, HPA042257" Enhanced Approved "Mid piece" NA NA "Cluster 42: Retina - Visual perception" "Cluster 46: Brainstem - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 107: Ciliated cells - Cilia assembly & function" "Mid piece" "HPA027253: , HPA042257: " "unprognostic (1.28e-1)" "unprognostic (3.23e-1)" "unprognostic (1.38e-1)" "unprognostic (5.44e-2)" RP1L1 DCDC4B ENSG00000183638 "RP1 like 1" Q8IWN7 8 10606349-10712187 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Sensory transduction, Vision" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 111 "retina: 41.0" "Group enriched" "Detected in some" 7 "Cone photoreceptor cells: 12.4;Rod photoreceptor cells: 17.1" "Low cell type specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA024686, HPA024744" Enhanced NA NA "Cluster 42: Retina - Visual perception" "Cluster 1: Neuronal - Visual perception" "Cluster 79: Photoreceptor cells - Phototransduction" "HPA024686: , HPA024744: " "unprognostic (9.00e-2)" RP2 "NM23-H10, NME10, TBCCD2" ENSG00000102218 "RP2 activator of ARL3 GTPase" O75695 X 46837043-46882358 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "GTPase activation" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 46.7" "Cell type enhanced" "Detected in all" "Kupffer cells: 109.7;Monocyte progenitors: 164.7;monocytes: 175.1;Neutrophil progenitors: 261.9;Neutrophils: 524.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000234, HPA000909" Uncertain Approved "Nucleoplasm,Nuclear bodies,Vesicles,Plasma membrane,Cytosol,Acrosome,Mid piece,Principal piece,End piece" NA NA 6700 "Cluster 40: Monocytes - Innate immune response" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 22: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 39 "Plasma membrane, Mid piece, Principal piece, End piece" "Nucleoplasm, Nuclear bodies, Vesicles, Cytosol, Acrosome" "HPA000234: , HPA000909: " "unprognostic (1.64e-1)" "unprognostic (6.29e-2)" "unprognostic (1.36e-1)" "unprognostic (1.77e-2)" "unprognostic (1.37e-2)" "unprognostic (7.54e-2)" "unprognostic (2.58e-1)" "unprognostic (8.19e-2)" "unprognostic (3.56e-1)" "unprognostic (4.88e-2)" "potential prognostic favorable (1.87e-7)" "unprognostic (2.20e-2)" "unprognostic (2.68e-1)" "potential prognostic unfavorable (6.72e-4)" "unprognostic (2.80e-1)" "unprognostic (3.31e-2)" "unprognostic (9.49e-2)" "unprognostic (8.98e-2)" "unprognostic (4.42e-1)" "unprognostic (1.53e-1)" "unprognostic (1.21e-2)" "unprognostic (3.15e-2)" "unprognostic (3.76e-1)" "unprognostic (1.19e-1)" "unprognostic (4.88e-2)" "unprognostic (2.52e-1)" "unprognostic (3.18e-2)" "unprognostic (4.25e-2)" "unprognostic (2.80e-1)" "unprognostic (4.36e-2)" "unprognostic (2.37e-1)" RP9 PAP-1 ENSG00000164610 "RP9 pre-mRNA splicing factor" Q8TA86 7 33094797-33109405 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 67.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031523, HPA050778" Uncertain Enhanced Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 52: Non-specific - Cellular respiration" "Cluster 25: Non-specific - Transcription" "Cluster 67: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 13 Nucleoplasm "Vesicles, Cytosol" "HPA031523: , HPA050778: " "unprognostic (1.71e-2)" "unprognostic (2.13e-1)" "unprognostic (1.28e-1)" "unprognostic (1.99e-2)" "unprognostic (1.33e-3)" "unprognostic (5.68e-2)" "unprognostic (6.42e-2)" "unprognostic (5.93e-2)" "unprognostic (3.03e-3)" "unprognostic (8.43e-3)" "unprognostic (4.60e-3)" "unprognostic (8.31e-2)" "unprognostic (6.43e-2)" "validated prognostic unfavorable (1.34e-4)" "validated prognostic unfavorable (3.32e-4)" "unprognostic (1.11e-3)" "unprognostic (4.64e-2)" "unprognostic (1.69e-2)" "unprognostic (2.83e-3)" "unprognostic (2.89e-1)" "unprognostic (1.43e-1)" "unprognostic (3.92e-3)" "unprognostic (9.74e-3)" "unprognostic (9.50e-2)" "unprognostic (2.29e-1)" "unprognostic (2.13e-1)" "unprognostic (2.94e-2)" "unprognostic (2.80e-1)" "unprognostic (1.89e-1)" "unprognostic (1.79e-1)" "unprognostic (4.52e-1)" RPA1 "HSSB, REPA1, RF-A, RP-A, RPA70" ENSG00000132383 "Replication protein A1" P27694 17 1829702-1900082 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, DNA replication" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 184.2;Platelets: 166.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004563, HPA006914, HPA046497" Supported Enhanced Nucleoplasm NA NA 17000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 42: Non-specific - Unknown function" "Cluster 47: Platelets - Hemostasis" 439 Nucleoplasm "CAB004563: , HPA006914: , HPA046497: " "unprognostic (2.23e-1)" "unprognostic (9.45e-2)" "unprognostic (7.63e-3)" "unprognostic (1.49e-1)" "unprognostic (1.16e-1)" "unprognostic (2.20e-1)" "unprognostic (3.07e-1)" "unprognostic (1.32e-1)" "unprognostic (4.64e-2)" "potential prognostic unfavorable (2.24e-5)" "potential prognostic favorable (1.16e-6)" "unprognostic (1.34e-2)" "unprognostic (2.24e-1)" "validated prognostic unfavorable (1.08e-5)" "validated prognostic unfavorable (9.50e-4)" "unprognostic (2.08e-2)" "unprognostic (4.21e-2)" "unprognostic (1.04e-1)" "unprognostic (5.18e-2)" "unprognostic (1.53e-1)" "unprognostic (5.93e-2)" "unprognostic (4.17e-2)" "unprognostic (2.90e-2)" "unprognostic (1.25e-1)" "unprognostic (5.02e-2)" "unprognostic (1.25e-1)" "unprognostic (1.07e-1)" "unprognostic (2.91e-1)" "unprognostic (2.16e-1)" "unprognostic (1.89e-1)" "unprognostic (4.10e-2)" RPA2 ENSG00000117748 "Replication protein A2" P15927 1 27891524-27914746 "Cancer-related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, DNA replication" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 183.3;Early primary spermatocytes: 224.9;Oocytes: 267.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016538, HPA026306, HPA026309" Supported Enhanced "Nucleoplasm,Nuclear bodies" NA NA 33000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 61: Non-specific - Transcription" "Cluster 39: Astrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 24: Neutrophils - Innate immunity signal integration" 404 "Nucleoplasm, Nuclear bodies" "CAB016538: , HPA026306: , HPA026309: " "unprognostic (1.27e-1)" "unprognostic (1.48e-1)" "unprognostic (2.04e-1)" "unprognostic (3.45e-3)" "unprognostic (2.25e-1)" "unprognostic (1.04e-1)" "unprognostic (1.47e-1)" "unprognostic (1.20e-2)" "unprognostic (2.40e-3)" "unprognostic (1.94e-1)" "validated prognostic favorable (1.17e-5)" "validated prognostic favorable (6.54e-4)" "unprognostic (2.96e-1)" "potential prognostic unfavorable (4.49e-4)" "unprognostic (5.81e-3)" "unprognostic (2.36e-2)" "unprognostic (2.60e-1)" "unprognostic (4.48e-1)" "unprognostic (2.61e-2)" "unprognostic (6.44e-2)" "unprognostic (3.71e-2)" "unprognostic (1.10e-1)" "unprognostic (1.10e-2)" "unprognostic (2.19e-1)" "unprognostic (1.16e-1)" "unprognostic (1.08e-1)" "unprognostic (1.42e-2)" "unprognostic (2.28e-1)" "unprognostic (3.12e-2)" "unprognostic (2.69e-2)" "unprognostic (1.29e-1)" RPA3 REPA3 ENSG00000106399 "Replication protein A3" P35244 7 7636518-7718607 "Essential proteins, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, DNA replication" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 644.8;Extravillous trophoblasts: 307.9;Gastric progenitor cells: 580.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Stomach - Mitotic cells (Stomach), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005708 Approved NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 21: Non-specific - Metabolism" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 327 "HPA005708: " "unprognostic (2.39e-2)" "unprognostic (2.27e-3)" "unprognostic (2.04e-1)" "potential prognostic favorable (1.83e-4)" "unprognostic (5.96e-2)" "unprognostic (2.81e-1)" "potential prognostic unfavorable (3.05e-5)" "unprognostic (3.91e-3)" "unprognostic (1.61e-2)" "unprognostic (6.88e-2)" "potential prognostic favorable (3.50e-4)" "unprognostic (2.63e-2)" "unprognostic (2.27e-2)" "validated prognostic unfavorable (9.62e-5)" "validated prognostic unfavorable (2.59e-4)" "potential prognostic unfavorable (9.99e-4)" "unprognostic (4.26e-2)" "unprognostic (5.82e-2)" "unprognostic (1.43e-1)" "unprognostic (3.54e-1)" "potential prognostic unfavorable (5.87e-4)" "unprognostic (4.14e-2)" "unprognostic (1.58e-3)" "unprognostic (8.24e-2)" "unprognostic (4.40e-2)" "unprognostic (1.80e-1)" "unprognostic (1.14e-2)" "unprognostic (2.01e-2)" "unprognostic (1.79e-1)" "unprognostic (1.99e-1)" "unprognostic (1.48e-1)" RPA4 HSU24186 ENSG00000204086 "Replication protein A4" Q13156 X 96883908-96885467 "Predicted intracellular proteins" "DNA damage, DNA repair" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "testis: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA066010 Approved Supported Nucleoplasm NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 67: Testis - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 50: Lymphoma - Unknown function" 23 Nucleoplasm "HPA066010: " "unprognostic (2.21e-2)" "unprognostic (8.06e-3)" "unprognostic (4.32e-3)" "unprognostic (5.69e-3)" RPAIN "hRIP, MGC4189, RIP" ENSG00000129197 "RPA interacting protein" Q86UA6 17 5419641-5432877 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023924, HPA031526" Approved Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 100: Stratified epithelial cells - Barrier functions" 1 "Nucleoli fibrillar center" Nucleoplasm "HPA023924: , HPA031526: " "unprognostic (3.86e-2)" "unprognostic (1.91e-2)" "unprognostic (3.10e-2)" "unprognostic (4.01e-2)" "unprognostic (2.48e-1)" "unprognostic (9.46e-2)" "unprognostic (2.36e-1)" "potential prognostic favorable (8.17e-4)" "unprognostic (1.39e-1)" "unprognostic (2.93e-2)" "potential prognostic favorable (7.18e-5)" "unprognostic (1.96e-2)" "unprognostic (7.11e-3)" "unprognostic (2.27e-1)" "unprognostic (3.00e-2)" "unprognostic (1.32e-1)" "unprognostic (5.37e-2)" "unprognostic (5.42e-2)" "unprognostic (8.64e-2)" "unprognostic (6.10e-3)" "unprognostic (2.95e-1)" "unprognostic (8.60e-3)" "unprognostic (2.05e-2)" "unprognostic (5.68e-3)" "unprognostic (4.35e-2)" "unprognostic (6.77e-2)" "unprognostic (1.34e-2)" "unprognostic (2.96e-1)" "unprognostic (1.49e-1)" "unprognostic (3.41e-1)" "potential prognostic favorable (1.52e-5)" RPAP1 "DKFZP727M111, FLJ12732, KIAA1403, MGC858" ENSG00000103932 "RNA polymerase II associated protein 1" Q9BWH6 15 41517176-41544269 "Essential proteins, Predicted intracellular proteins, Predicted membrane proteins" Transcription "DNA-binding, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041739 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" 23 Nucleoplasm Cytosol "HPA041739: " "unprognostic (3.30e-1)" "unprognostic (2.79e-3)" "unprognostic (3.37e-1)" "unprognostic (1.10e-3)" "unprognostic (2.90e-1)" "unprognostic (2.20e-1)" "unprognostic (3.40e-1)" "unprognostic (8.10e-2)" "unprognostic (7.79e-2)" "unprognostic (4.68e-3)" "potential prognostic favorable (3.22e-7)" "unprognostic (9.23e-2)" "unprognostic (1.52e-1)" "unprognostic (5.27e-3)" "unprognostic (3.03e-3)" "unprognostic (3.11e-2)" "unprognostic (1.35e-2)" "unprognostic (1.71e-1)" "unprognostic (5.90e-2)" "unprognostic (4.39e-2)" "unprognostic (9.64e-2)" "unprognostic (3.82e-1)" "unprognostic (7.54e-3)" "unprognostic (2.31e-1)" "unprognostic (3.23e-2)" "unprognostic (3.57e-1)" "unprognostic (8.45e-2)" "unprognostic (1.82e-1)" "unprognostic (1.64e-1)" "unprognostic (6.09e-3)" "unprognostic (4.11e-2)" RPAP2 "C1orf82, FLJ13150, Rtr1" ENSG00000122484 "RNA polymerase II associated protein 2" Q8IXW5 1 92299059-92402056 "Enzymes, Essential proteins, Predicted membrane proteins" "Transcription, Transcription regulation" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046443 Approved Supported "Nucleoli,Primary cilium,Cytosol" No No "Cluster 24: Non-specific - Transcription" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 9: Non-specific - Receptor signaling" "Cluster 56: Non-specific - Sensory perception" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 100 "Nucleoli, Cytosol" "Primary cilium" "HPA046443: " "unprognostic (1.69e-1)" "unprognostic (1.27e-1)" "unprognostic (1.89e-1)" "unprognostic (1.11e-2)" "unprognostic (1.20e-1)" "unprognostic (1.26e-1)" "unprognostic (2.67e-2)" "unprognostic (2.16e-2)" "unprognostic (1.56e-2)" "unprognostic (1.06e-3)" "unprognostic (1.37e-1)" "unprognostic (4.05e-3)" "unprognostic (1.70e-1)" "unprognostic (2.46e-2)" "unprognostic (4.94e-3)" "unprognostic (1.63e-1)" "unprognostic (1.75e-1)" "unprognostic (1.00e-1)" "unprognostic (1.34e-1)" "unprognostic (7.65e-2)" "unprognostic (5.99e-2)" "unprognostic (3.02e-1)" "unprognostic (7.62e-2)" "unprognostic (2.37e-1)" "unprognostic (1.06e-2)" "unprognostic (3.47e-2)" "unprognostic (6.69e-2)" "unprognostic (4.23e-2)" "unprognostic (2.72e-1)" "unprognostic (1.97e-3)" "unprognostic (1.41e-1)" RPAP3 "FLJ21908, hSpagh, spag, Tah1" ENSG00000005175 "RNA polymerase II associated protein 3" Q9H6T3 12 47661249-47706030 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038311, HPA038312" Enhanced Enhanced "Primary cilium,Primary cilium tip,Basal body,Cytosol,Acrosome" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 102 Cytosol "Primary cilium, Primary cilium tip, Basal body, Acrosome" "HPA038311: , HPA038312: " "unprognostic (2.85e-2)" "unprognostic (2.77e-2)" "unprognostic (2.74e-2)" "unprognostic (1.61e-1)" "unprognostic (3.05e-3)" "unprognostic (8.14e-2)" "unprognostic (2.83e-1)" "unprognostic (3.65e-1)" "unprognostic (7.57e-2)" "unprognostic (5.77e-2)" "potential prognostic favorable (2.33e-5)" "unprognostic (2.63e-1)" "unprognostic (4.47e-2)" "potential prognostic unfavorable (8.42e-6)" "unprognostic (9.13e-2)" "unprognostic (4.18e-3)" "unprognostic (8.25e-3)" "unprognostic (2.07e-2)" "unprognostic (5.69e-2)" "unprognostic (2.87e-1)" "unprognostic (5.47e-3)" "unprognostic (4.66e-3)" "potential prognostic unfavorable (5.73e-4)" "unprognostic (1.83e-2)" "unprognostic (4.79e-2)" "unprognostic (1.65e-1)" "unprognostic (8.06e-3)" "unprognostic (1.49e-1)" "unprognostic (4.11e-1)" "unprognostic (2.29e-2)" "unprognostic (2.01e-1)" RPE ENSG00000197713 Ribulose-5-phosphate-3-epimerase Q96AT9 2 210002565-210022260 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA036498, HPA036499" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 59000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 61: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 1 Cytosol "Nucleoplasm, Plasma membrane" "HPA036498: , HPA036499: " "unprognostic (2.32e-1)" "unprognostic (1.41e-2)" "unprognostic (1.20e-1)" "unprognostic (9.07e-3)" "unprognostic (1.96e-1)" "unprognostic (3.44e-2)" "unprognostic (1.79e-1)" "unprognostic (4.13e-1)" "unprognostic (1.53e-1)" "unprognostic (3.46e-2)" "potential prognostic favorable (2.58e-6)" "unprognostic (2.26e-1)" "unprognostic (4.38e-2)" "validated prognostic unfavorable (8.73e-5)" "validated prognostic unfavorable (7.43e-4)" "potential prognostic unfavorable (1.17e-4)" "unprognostic (4.91e-2)" "unprognostic (1.25e-1)" "unprognostic (6.96e-2)" "unprognostic (3.49e-2)" "unprognostic (2.41e-2)" "potential prognostic unfavorable (5.33e-4)" "unprognostic (2.74e-2)" "unprognostic (2.01e-2)" "unprognostic (1.52e-1)" "unprognostic (3.17e-1)" "unprognostic (3.34e-2)" "unprognostic (1.02e-1)" "unprognostic (1.15e-1)" "unprognostic (1.62e-1)" "unprognostic (2.86e-2)" RPE65 "BCO3, LCA2, rd12, RP20" ENSG00000116745 "Retinoid isomerohydrolase RPE65" Q16518 1 68428822-68449954 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Sensory transduction, Vision" "Hydrolase, Isomerase" "Disease variant, FDA approved drug targets, Leber congenital amaurosis, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.2;choroid plexus: 3.5;retina: 7.8;seminal vesicle: 4.2" "Cell type enriched" "Detected in some" 149 "Retinal pigment epithelial cells: 7170.3" "Group enriched" "Detected in some" 13 "astrocyte: 24.9;choroid plexus epithelial cell: 17.4;ependymal cell: 37.0" "Cancer enriched" "Detected in some" 8 "Glioblastoma Multiforme (TCGA): 9.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "pancreatic cancer: 3.2;Rhabdoid: 4.8" "Adipose subcutaneous - Smooth muscle cells" "Group enriched" "Detected in many" 4 "amygdala: 3.2;basal ganglia: 2.5;cerebral cortex: 3.9;hippocampal formation: 2.5" "Low region specificity" "Detected in many" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 19: Astrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" 3 "unprognostic (7.29e-3)" "unprognostic (1.25e-1)" "unprognostic (7.42e-2)" RPEL1 ENSG00000235376 "Ribulose-5-phosphate-3-epimerase like 1" Q2QD12 10 103245887-103248016 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Gastric progenitor cells: 1.3;Retinal amacrine cells: 1.4;Retinal bipolar cells: 2.1;Retinal ganglion cells: 7.7;Rod photoreceptor cells: 2.4" "Cell type enhanced" "Detected in some" "lower rhombic lip: 2.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA036498, HPA036499" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 37: Neurons - Mixed function" "Cluster 61: BICR 18 - Protein kinases" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" Cytosol "Nucleoplasm, Plasma membrane" "HPA036498: , HPA036499: " RPF1 BXDC5 ENSG00000117133 "Ribosome production factor 1 homolog" Q9H9Y2 1 84479259-84498352 "Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 197.3;Oocytes: 211.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024642 Supported Supported Nucleoli No No "Cluster 3: Non-specific - Nuclear processes" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 47 Nucleoli "HPA024642: " "unprognostic (1.16e-1)" "unprognostic (8.41e-2)" "unprognostic (5.90e-3)" "unprognostic (7.04e-2)" "unprognostic (3.13e-3)" "unprognostic (2.20e-1)" "unprognostic (2.31e-2)" "unprognostic (8.09e-2)" "unprognostic (2.54e-1)" "potential prognostic unfavorable (5.30e-5)" "validated prognostic favorable (2.78e-5)" "validated prognostic favorable (5.63e-5)" "unprognostic (4.27e-2)" "potential prognostic unfavorable (1.10e-7)" "unprognostic (2.29e-3)" "unprognostic (3.00e-2)" "unprognostic (2.87e-2)" "unprognostic (4.31e-2)" "unprognostic (5.92e-2)" "unprognostic (6.09e-2)" "unprognostic (1.41e-1)" "unprognostic (1.75e-2)" "unprognostic (4.33e-1)" "unprognostic (1.10e-1)" "unprognostic (1.96e-2)" "unprognostic (1.64e-1)" "unprognostic (7.01e-2)" "unprognostic (3.70e-1)" "unprognostic (3.58e-2)" "unprognostic (2.03e-1)" "unprognostic (1.90e-1)" RPF2 "bA397G5.4, BXDC1, FLJ21087" ENSG00000197498 "Ribosome production factor 2 homolog" Q9H7B2 6 110982015-111028263 "Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 192.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035475 Supported Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 3: Non-specific - Nuclear processes" "Cluster 70: Non-specific - Protein processing" "Cluster 55: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 66 "Nucleoli, Nucleoli rim" "Nucleoplasm, Mitotic chromosome" "HPA035475: " "potential prognostic unfavorable (4.91e-4)" "unprognostic (1.47e-3)" "unprognostic (4.21e-2)" "unprognostic (1.61e-2)" "unprognostic (3.00e-1)" "unprognostic (3.34e-2)" "unprognostic (1.20e-1)" "unprognostic (1.72e-1)" "potential prognostic unfavorable (4.13e-4)" "unprognostic (8.76e-3)" "unprognostic (3.63e-2)" "unprognostic (2.22e-1)" "unprognostic (4.00e-3)" "validated prognostic unfavorable (3.69e-6)" "validated prognostic unfavorable (9.97e-5)" "unprognostic (8.54e-3)" "potential prognostic unfavorable (1.52e-4)" "unprognostic (2.11e-3)" "unprognostic (2.33e-2)" "unprognostic (4.02e-2)" "unprognostic (5.25e-3)" "unprognostic (3.90e-2)" "unprognostic (1.47e-3)" "unprognostic (3.04e-1)" "unprognostic (5.89e-2)" "unprognostic (1.70e-1)" "unprognostic (6.25e-2)" "unprognostic (1.99e-1)" "unprognostic (1.33e-1)" "unprognostic (5.86e-2)" "unprognostic (1.20e-1)" RPGR "COD1, CORDX1, CRD, RP15, RP3" ENSG00000156313 "Retinitis pigmentosa GTPase regulator" Q92834 X 38269163-38327544 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation, Sensory transduction, Vision" "Guanine-nucleotide releasing factor" "Cancer-related genes, Ciliopathy, Cone-rod dystrophy, Deafness, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 293.5;Corticotrophs: 199.2;Endometrial ciliated cells: 393.2;Ependymal cells: 346.1;Epididymal efferent duct ciliated cells: 295.1;Fallopian tube ciliated cells: 250.1;Lymphatic endothelial cells: 242.9;Neutrophils: 273.4;Respiratory ciliated cells: 254.2;Somatotrophs: 360.5" "Group enriched" "Detected in all" 4 "choroid plexus epithelial cell: 254.9;endothelial cell: 189.0;ependymal cell: 378.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 14.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 14.8" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001593, HPA073455" Approved Supported "Golgi apparatus,Primary cilium,Mitochondria,Cytosol,Mid piece,Principal piece,End piece" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 36: Non-specific - mRNA processing" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 15 "Golgi apparatus, Primary cilium" "Mitochondria, Cytosol, Mid piece, Principal piece, End piece" "HPA001593: , HPA073455: " "unprognostic (1.50e-1)" "unprognostic (7.22e-2)" "unprognostic (2.35e-1)" "unprognostic (3.90e-2)" "unprognostic (2.45e-1)" "unprognostic (4.84e-2)" "unprognostic (1.65e-1)" "unprognostic (3.24e-2)" "unprognostic (5.89e-3)" "unprognostic (2.03e-1)" "unprognostic (2.78e-2)" "unprognostic (1.10e-2)" "unprognostic (6.98e-2)" "unprognostic (5.17e-2)" "unprognostic (5.69e-2)" "unprognostic (1.74e-1)" "unprognostic (3.20e-1)" "unprognostic (1.81e-1)" "unprognostic (3.71e-2)" "unprognostic (1.89e-1)" "unprognostic (7.31e-2)" "potential prognostic favorable (1.53e-4)" "unprognostic (2.66e-3)" "unprognostic (1.01e-1)" "unprognostic (1.44e-1)" "unprognostic (1.63e-2)" "unprognostic (6.02e-2)" "unprognostic (1.73e-1)" "unprognostic (4.42e-2)" "unprognostic (2.21e-2)" "unprognostic (1.48e-1)" RPGRIP1 "CORD13, LCA6, RGI1, RPGRIP" ENSG00000092200 "RPGR interacting protein 1" Q96KN7 14 21280083-21351301 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Ciliopathy, Cone-rod dystrophy, Disease variant, Glaucoma, Leber congenital amaurosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 82 "retina: 171.2;testis: 55.4" "Group enriched" "Detected in many" 4 "Cone photoreceptor cells: 979.2;Rod photoreceptor cells: 602.9" "Group enriched" "Detected in many" 4 "central nervous system macrophage: 11.9;hippocampal CA4: 3.3" "Cancer enriched" "Detected in single" 4 "Testicular Germ Cell Tumor (TCGA): 3.3" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "neutrophil: 8.8" "Group enriched" "Detected in many" 28 "dendritic cells: 3.2;granulocytes: 8.8;monocytes: 3.6" "Low cancer specificity" "Detected in single" "Breast - Breast glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA042955, HPA060190" Supported Supported Approved "Vesicles,Microtubules,Cytokinetic bridge,Primary cilium,Primary cilium tip,Cytosol" Yes NA "Cluster 21: Neutrophils - Unknown function" "Cluster 42: Retina - Visual perception" "Cluster 6: Non-specific - Immune response" "Cluster 1: Neuronal - Visual perception" "Cluster 79: Photoreceptor cells - Phototransduction" 28 "Vesicles, Microtubules, Primary cilium" "Cytokinetic bridge, Primary cilium tip, Cytosol" "HPA042955: , HPA060190: " "unprognostic (1.04e-1)" "unprognostic (1.31e-1)" "unprognostic (1.40e-2)" "unprognostic (1.20e-2)" "unprognostic (1.96e-1)" RPGRIP1L "CORS3, FTM, JBTS7, KIAA1005, MKS5, NPHP8, PPP1R134" ENSG00000103494 "RPGRIP1 like" Q68CZ1 16 53598153-53703938 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant, Joubert syndrome, Meckel syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 12.6" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 98.0;Ependymal cells: 270.7;Fallopian tube ciliated cells: 85.7;Lactotrophs: 94.8;Respiratory ciliated cells: 177.4;Somatotrophs: 98.7;Thyrotrophs: 102.7" "Cell type enhanced" "Detected in all" "ependymal cell: 306.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039405, HPA040530" Uncertain Approved "Plasma membrane,Primary cilium,Basal body,Cytosol" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 61: Non-specific - Transcription" "Cluster 17: Choroid plexus - Cilium" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 34: Ciliated cells - Cilia assembly & function" 48 "Plasma membrane, Cytosol" "Primary cilium, Basal body" "HPA039405: , HPA040530: " "unprognostic (8.42e-2)" "potential prognostic unfavorable (6.22e-4)" "unprognostic (2.13e-1)" "unprognostic (3.49e-2)" "unprognostic (9.20e-2)" "unprognostic (4.16e-2)" "unprognostic (1.17e-1)" "unprognostic (2.09e-1)" "unprognostic (1.51e-2)" "unprognostic (2.00e-1)" "unprognostic (3.53e-3)" "unprognostic (1.33e-1)" "unprognostic (2.04e-1)" "potential prognostic unfavorable (8.49e-4)" "unprognostic (1.19e-1)" "unprognostic (3.29e-2)" "unprognostic (1.00e-1)" "unprognostic (1.45e-1)" "unprognostic (2.58e-1)" "unprognostic (1.38e-3)" "unprognostic (1.88e-3)" "unprognostic (3.00e-3)" "unprognostic (2.46e-2)" "potential prognostic favorable (4.08e-4)" "unprognostic (3.37e-1)" "unprognostic (1.35e-3)" "unprognostic (3.27e-2)" "unprognostic (3.58e-1)" "potential prognostic unfavorable (8.90e-4)" "unprognostic (1.24e-2)" RPH3A "exophilin-1, KIAA0985, rabphilin" ENSG00000089169 "Rabphilin 3A" Q9Y2J0 12 112570380-112898881 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 115.4" "Cell type enhanced" "Detected in many" "Bergmann glia: 88.0;Brain excitatory neurons: 100.5;Brain inhibitory neurons: 145.8;Ependymal cells: 151.6;Neutrophils: 244.9;Oligodendrocyte progenitor cells: 41.5;Other brain neurons: 220.1;Retinal amacrine cells: 125.9" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in some" 7 "Glioblastoma Multiforme (TCGA): 16.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 6.3;intermediate monocyte: 3.0;neutrophil: 2.2;non-classical monocyte: 4.6" "Group enriched" "Detected in many" 5 "granulocytes: 2.2;monocytes: 6.3" "Group enriched" "Detected in many" 5 "Myeloma: 7.4;Neuroblastoma: 17.0" "Adipose visceral - Neutrophils, Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002475 Enhanced NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 7 "HPA002475: " "unprognostic (2.15e-1)" "unprognostic (6.45e-3)" "unprognostic (6.49e-2)" "unprognostic (1.63e-1)" "unprognostic (5.99e-2)" "unprognostic (1.01e-3)" "unprognostic (2.39e-3)" "unprognostic (1.73e-1)" RPH3AL Noc2 ENSG00000181031 "Rabphilin 3A like (without C2 domains)" Q9UNE2 17 212389-386254 "Predicted intracellular proteins" Exocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 49.6;pituitary gland: 42.4" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 46.0;Loop of henle epithelial cells: 62.7;Papillary tip epithelial cells: 90.5;Podocytes: 74.1;Proximal tubule cells: 58.2;Renal collecting duct intercalated cells: 82.1;Renal collecting duct principal cells: 150.6;Renal connecting tubule cells: 138.2" "Cell type enhanced" "Detected in all" "endothelial cell: 49.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Pituitary gland - Somatotropes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA024311 Approved NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 70: Non-specific - Protein processing" "Cluster 49: Hindbrain - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 105: Non-specific - Mixed function" 10 "HPA024311: " "unprognostic (6.09e-2)" "unprognostic (2.63e-3)" "unprognostic (3.52e-3)" "potential prognostic favorable (5.88e-5)" "unprognostic (3.96e-1)" "unprognostic (1.95e-1)" "unprognostic (3.10e-2)" "unprognostic (2.18e-2)" "unprognostic (1.87e-1)" "unprognostic (4.86e-2)" "potential prognostic favorable (1.22e-4)" "unprognostic (1.35e-1)" "unprognostic (8.15e-2)" "unprognostic (8.04e-2)" "unprognostic (9.45e-3)" "unprognostic (2.41e-1)" "unprognostic (2.49e-1)" "unprognostic (1.09e-2)" "unprognostic (1.21e-1)" "unprognostic (2.28e-1)" "unprognostic (1.30e-1)" "unprognostic (2.52e-2)" "unprognostic (1.98e-2)" "unprognostic (2.77e-1)" "unprognostic (1.69e-1)" "unprognostic (4.57e-3)" "unprognostic (1.88e-1)" "unprognostic (1.54e-1)" "unprognostic (3.15e-1)" "unprognostic (1.21e-1)" RPIA ENSG00000153574 "Ribose 5-phosphate isomerase A" P49247 2 88691673-88750929 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Isomerase "Disease variant, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 84.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 289.4;Esophageal apical cells: 284.9;Migrating cytotrophoblasts: 251.1;Syncytiotrophoblasts: 244.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042620, HPA057954" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA 810000 "Cluster 45: Eosinophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 25 "Nucleoplasm, Vesicles, Plasma membrane" "HPA042620: , HPA057954: " "unprognostic (4.00e-2)" "unprognostic (3.75e-1)" "unprognostic (2.73e-1)" "unprognostic (5.92e-2)" "unprognostic (3.37e-2)" "potential prognostic favorable (6.92e-4)" "unprognostic (6.62e-2)" "unprognostic (1.41e-2)" "unprognostic (2.07e-2)" "unprognostic (7.29e-2)" "unprognostic (1.76e-2)" "unprognostic (4.97e-2)" "potential prognostic unfavorable (1.12e-4)" "validated prognostic unfavorable (2.30e-5)" "validated prognostic unfavorable (1.12e-5)" "unprognostic (1.73e-2)" "unprognostic (1.35e-1)" "unprognostic (9.64e-3)" "unprognostic (3.67e-2)" "unprognostic (3.06e-1)" "unprognostic (1.36e-1)" "unprognostic (4.17e-2)" "unprognostic (1.02e-1)" "unprognostic (9.15e-2)" "unprognostic (1.93e-1)" "unprognostic (1.76e-1)" "unprognostic (2.65e-2)" "unprognostic (8.12e-2)" "unprognostic (1.46e-1)" "unprognostic (6.48e-3)" "unprognostic (3.65e-1)" RPL10 "DXS648, DXS648E, FLJ23544, L10, NOV, QM" ENSG00000147403 "Ribosomal protein L10" P27635 X 154389955-154409168 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Developmental protein, Ribonucleoprotein, Ribosomal protein" "Autism, Autism spectrum disorder, Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Decidual stromal cells: 20460.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "CAB010339, HPA011311" Enhanced Enhanced "Endoplasmic reticulum,Cytosol" NA NA 330000 "Cluster 18: Non-specific - Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 348 "Endoplasmic reticulum, Cytosol" "CAB010339: , HPA011311: " "unprognostic (9.90e-3)" "potential prognostic favorable (6.64e-4)" "unprognostic (5.62e-2)" "unprognostic (9.72e-3)" "unprognostic (1.63e-1)" "unprognostic (2.49e-2)" "unprognostic (1.72e-2)" "potential prognostic favorable (1.46e-4)" "unprognostic (4.51e-2)" "unprognostic (2.55e-1)" "unprognostic (1.05e-3)" "unprognostic (1.29e-2)" "potential prognostic unfavorable (4.32e-4)" "unprognostic (7.07e-2)" "potential prognostic unfavorable (1.43e-4)" "unprognostic (4.54e-1)" "unprognostic (1.23e-2)" "unprognostic (1.48e-2)" "unprognostic (7.32e-2)" "unprognostic (1.26e-1)" "unprognostic (4.01e-1)" "unprognostic (1.57e-2)" "unprognostic (8.26e-3)" "unprognostic (3.46e-1)" "unprognostic (7.47e-2)" "unprognostic (3.02e-1)" "unprognostic (1.53e-1)" "unprognostic (2.02e-1)" "unprognostic (7.49e-2)" "unprognostic (1.08e-1)" "unprognostic (5.87e-2)" RPL10A "Csa-19, L10A, NEDD6" ENSG00000198755 "Ribosomal protein L10a" P62906 6 35468401-35470785 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Decidual stromal cells: 8699.6;Esophageal basal cells: 7877.3;Esophageal suprabasal cells: 8236.0;Extravillous trophoblasts: 6872.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053803, HPA077110" Approved Supported "Nucleoli,Endoplasmic reticulum,Cytosol" NA NA 450000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 220 "Nucleoli, Endoplasmic reticulum, Cytosol" "HPA053803: , HPA077110: " "unprognostic (6.21e-3)" "unprognostic (5.07e-2)" "unprognostic (1.39e-1)" "potential prognostic favorable (2.27e-4)" "unprognostic (2.22e-1)" "unprognostic (3.24e-1)" "unprognostic (2.12e-1)" "unprognostic (8.48e-2)" "unprognostic (9.91e-3)" "unprognostic (1.69e-1)" "unprognostic (1.06e-3)" "potential prognostic favorable (5.89e-4)" "unprognostic (2.83e-2)" "unprognostic (5.53e-3)" "unprognostic (6.90e-3)" "unprognostic (2.15e-1)" "unprognostic (1.01e-2)" "unprognostic (2.59e-2)" "unprognostic (3.68e-1)" "unprognostic (3.56e-2)" "unprognostic (3.82e-2)" "unprognostic (1.60e-2)" "unprognostic (2.38e-2)" "unprognostic (2.10e-1)" "unprognostic (3.70e-3)" "unprognostic (3.38e-1)" "unprognostic (8.16e-2)" "unprognostic (2.91e-2)" "unprognostic (4.40e-1)" "unprognostic (8.00e-2)" "unprognostic (8.90e-3)" RPL10L ENSG00000165496 "Ribosomal protein L10 like" Q96L21 14 46651010-46651781 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Differentiation, Meiosis, Spermatogenesis" "Ribonucleoprotein, Ribosomal protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 35 "testis: 91.6" "Group enriched" "Detected in some" 16 "Early spermatids: 527.2;Late primary spermatocytes: 892.1;Late spermatids: 279.5" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 16 "Testicular Germ Cell Tumor (TCGA): 10.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "head and neck cancer: 11.2" "Colon - Colon enterocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA011311 Uncertain Approved "Endoplasmic reticulum,Cytosol" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 61: BICR 18 - Protein kinases" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 25 "Endoplasmic reticulum, Cytosol" "HPA011311: " "unprognostic (3.58e-2)" "unprognostic (5.96e-2)" "unprognostic (9.26e-2)" "unprognostic (2.41e-1)" RPL11 "L11, uL5" ENSG00000142676 "Ribosomal protein L11" P62913 1 23691742-23696835 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding" "Diamond-Blackfan anemia, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 10127.3;Esophageal suprabasal cells: 11803.3;Extravillous trophoblasts: 9937.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002734 Approved NA NA 240000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 354 "HPA002734: " "potential prognostic unfavorable (9.40e-4)" "unprognostic (7.39e-3)" "unprognostic (1.11e-1)" "unprognostic (2.76e-3)" "unprognostic (5.83e-2)" "unprognostic (1.16e-1)" "unprognostic (2.23e-1)" "unprognostic (2.83e-2)" "unprognostic (9.60e-2)" "unprognostic (8.81e-2)" "unprognostic (2.84e-1)" "unprognostic (7.93e-2)" "unprognostic (3.71e-2)" "unprognostic (2.15e-3)" "potential prognostic unfavorable (2.14e-6)" "unprognostic (8.11e-2)" "unprognostic (5.39e-2)" "unprognostic (1.28e-2)" "unprognostic (2.62e-2)" "unprognostic (9.83e-3)" "unprognostic (6.57e-2)" "unprognostic (1.35e-2)" "unprognostic (2.76e-1)" "unprognostic (4.17e-2)" "unprognostic (5.70e-3)" "unprognostic (2.72e-1)" "unprognostic (1.63e-1)" "unprognostic (1.74e-1)" "unprognostic (7.20e-2)" "unprognostic (7.82e-2)" "unprognostic (4.41e-2)" RPL12 L12 ENSG00000197958 "Ribosomal protein L12" P30050 9 127447674-127451406 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Breast secretory cells: 8579.3;Decidual stromal cells: 13221.4;Esophageal apical cells: 8327.6;Esophageal basal cells: 8725.9;Esophageal suprabasal cells: 9243.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" HPA003403 Approved Approved "Golgi apparatus,Vesicles" NA NA 260000 "Cluster 18: Non-specific - Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 110 "Golgi apparatus" Vesicles "HPA003403: " "unprognostic (5.41e-3)" "unprognostic (2.77e-2)" "unprognostic (1.99e-1)" "unprognostic (3.68e-3)" "unprognostic (2.38e-1)" "unprognostic (8.09e-2)" "unprognostic (2.73e-2)" "unprognostic (9.90e-3)" "potential prognostic unfavorable (2.68e-4)" "unprognostic (1.37e-1)" "unprognostic (2.23e-1)" "unprognostic (1.81e-1)" "unprognostic (2.80e-3)" "potential prognostic unfavorable (3.53e-4)" "unprognostic (1.69e-3)" "unprognostic (2.03e-1)" "unprognostic (6.76e-3)" "unprognostic (1.42e-1)" "unprognostic (3.07e-1)" "potential prognostic unfavorable (1.57e-4)" "unprognostic (1.39e-1)" "unprognostic (5.08e-2)" "unprognostic (3.09e-1)" "unprognostic (2.12e-1)" "unprognostic (1.28e-1)" "unprognostic (3.72e-1)" "unprognostic (1.43e-1)" "unprognostic (4.91e-1)" "unprognostic (5.58e-1)" "unprognostic (4.03e-2)" "unprognostic (1.36e-1)" RPL13 "BBC1, D16S444E, L13" ENSG00000167526 "Ribosomal protein L13" P26373 16 89560677-89564542 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Decidual stromal cells: 15809.6;Esophageal suprabasal cells: 15062.6;Late spermatids: 18274.6" "Cell type enhanced" "Detected in all" "leukocyte: 812.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051702 Approved Enhanced "Nucleoli,Endoplasmic reticulum,Cytosol" NA NA 72000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 409 "Nucleoli, Endoplasmic reticulum, Cytosol" "HPA051702: " "potential prognostic unfavorable (9.28e-4)" "unprognostic (2.80e-2)" "unprognostic (5.26e-1)" "unprognostic (1.44e-2)" "unprognostic (3.25e-2)" "unprognostic (2.12e-2)" "unprognostic (4.65e-3)" "unprognostic (5.55e-3)" "unprognostic (4.64e-3)" "unprognostic (7.96e-2)" "unprognostic (2.52e-3)" "unprognostic (2.69e-3)" "unprognostic (3.31e-2)" "unprognostic (8.96e-3)" "unprognostic (1.52e-3)" "unprognostic (4.95e-2)" "unprognostic (5.50e-2)" "unprognostic (3.71e-1)" "unprognostic (3.67e-1)" "unprognostic (2.24e-3)" "unprognostic (2.06e-1)" "unprognostic (1.39e-1)" "unprognostic (2.87e-2)" "unprognostic (1.83e-1)" "unprognostic (1.12e-1)" "unprognostic (3.26e-1)" "unprognostic (3.61e-2)" "unprognostic (3.99e-3)" "unprognostic (1.40e-1)" "unprognostic (2.78e-1)" "unprognostic (5.90e-2)" RPL13A "L13A, TSTA1" ENSG00000142541 "Ribosomal protein L13a" P40429 19 49487510-49493057 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Translation regulation" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Decidual stromal cells: 15621.3;Esophageal apical cells: 11776.0;Esophageal basal cells: 14660.5;Esophageal suprabasal cells: 15607.6;Extravillous trophoblasts: 12038.8;Ovarian stromal cells: 12102.5" "Cell type enhanced" "Detected in all" "leukocyte: 321.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038751 Approved Approved Nucleoli,Cytosol NA NA 32000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 258 "Nucleoli, Cytosol" "HPA038751: " "unprognostic (1.29e-2)" "unprognostic (3.81e-3)" "unprognostic (1.49e-1)" "unprognostic (2.37e-3)" "unprognostic (1.85e-1)" "unprognostic (3.76e-1)" "unprognostic (1.91e-2)" "unprognostic (1.12e-1)" "unprognostic (1.73e-1)" "unprognostic (2.19e-1)" "unprognostic (2.64e-2)" "unprognostic (2.21e-1)" "unprognostic (6.17e-3)" "unprognostic (1.22e-2)" "potential prognostic unfavorable (1.43e-4)" "unprognostic (2.46e-2)" "unprognostic (3.35e-1)" "potential prognostic favorable (9.49e-4)" "unprognostic (1.60e-2)" "unprognostic (8.59e-3)" "unprognostic (6.94e-2)" "unprognostic (1.58e-1)" "unprognostic (6.34e-2)" "unprognostic (7.57e-2)" "unprognostic (6.33e-2)" "unprognostic (3.61e-1)" "unprognostic (5.22e-2)" "unprognostic (1.43e-1)" "unprognostic (4.77e-1)" "unprognostic (2.97e-1)" "unprognostic (1.35e-1)" RPL14 "CTG-B33, hRL14, L14, RL14" ENSG00000188846 "Ribosomal protein L14" P50914 3 40457292-40468587 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal basal cells: 5342.7;Esophageal suprabasal cells: 5342.7;Extravillous trophoblasts: 5255.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" HPA004136 Approved Supported "Endoplasmic reticulum,Cytosol" NA NA 94000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 294 "Endoplasmic reticulum, Cytosol" "HPA004136: " "unprognostic (1.59e-1)" "unprognostic (1.56e-1)" "unprognostic (1.29e-1)" "unprognostic (3.98e-3)" "unprognostic (3.19e-1)" "unprognostic (3.82e-2)" "unprognostic (5.07e-2)" "unprognostic (4.74e-2)" "unprognostic (7.27e-2)" "unprognostic (6.90e-2)" "unprognostic (5.36e-3)" "unprognostic (9.26e-2)" "unprognostic (1.11e-1)" "unprognostic (2.20e-2)" "potential prognostic unfavorable (1.36e-5)" "unprognostic (1.09e-1)" "unprognostic (8.76e-2)" "unprognostic (1.51e-1)" "unprognostic (3.86e-1)" "unprognostic (2.39e-1)" "unprognostic (4.21e-1)" "unprognostic (2.65e-1)" "unprognostic (2.50e-1)" "unprognostic (3.24e-2)" "potential prognostic favorable (1.20e-4)" "unprognostic (3.68e-1)" "unprognostic (7.61e-2)" "unprognostic (4.89e-3)" "unprognostic (2.22e-1)" "unprognostic (6.80e-2)" "unprognostic (1.12e-2)" RPL15 "EC45, L15, RPL10, RPLY10, RPYL10" ENSG00000174748 "Ribosomal protein L15" P61313 3 23916591-23924374 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Diamond-Blackfan anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Decidual stromal cells: 6904.6;Extravillous trophoblasts: 7079.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 200000 "Cluster 18: Non-specific - Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 174 "unprognostic (2.48e-2)" "unprognostic (1.90e-2)" "unprognostic (2.51e-2)" "unprognostic (2.48e-2)" "unprognostic (1.91e-1)" "unprognostic (4.33e-2)" "unprognostic (9.25e-2)" "unprognostic (5.52e-3)" "unprognostic (1.66e-1)" "unprognostic (1.46e-1)" "unprognostic (1.29e-2)" "unprognostic (4.88e-2)" "unprognostic (1.52e-1)" "validated prognostic unfavorable (1.03e-5)" "validated prognostic unfavorable (1.81e-6)" "unprognostic (2.92e-2)" "potential prognostic unfavorable (1.93e-5)" "unprognostic (1.28e-1)" "unprognostic (2.91e-1)" "unprognostic (2.69e-1)" "unprognostic (5.90e-2)" "unprognostic (8.07e-2)" "unprognostic (1.96e-1)" "unprognostic (6.92e-2)" "unprognostic (1.18e-2)" "unprognostic (3.06e-1)" "unprognostic (8.67e-2)" "unprognostic (1.48e-1)" "unprognostic (2.89e-1)" "unprognostic (3.16e-2)" "unprognostic (8.45e-2)" RPL17 "L17, rpL23" ENSG00000265681 "Ribosomal protein L17" P18621 18 49488453-49492508 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enteric stem cells: 725.7;Enteric transient amplifying cells: 611.7;Epididymal basal cells: 624.1;Epididymal efferent duct absorptive cells: 660.0;Epididymal principal cells: 447.8;Gastric chief cells: 873.6;Goblet cells: 416.5;Mucous neck cells: 572.0;Paneth cells: 510.5;Parietal cells: 489.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "HPA043724, HPA046385" Supported Supported "Endoplasmic reticulum,Cytosol" NA NA 170000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 198 "Endoplasmic reticulum, Cytosol" "HPA043724: , HPA046385: " "unprognostic (6.25e-3)" "unprognostic (1.28e-1)" "unprognostic (2.67e-1)" "unprognostic (2.68e-3)" "unprognostic (9.41e-2)" "unprognostic (3.26e-1)" "unprognostic (3.32e-1)" "unprognostic (1.52e-2)" "unprognostic (1.76e-2)" "unprognostic (3.41e-1)" "unprognostic (7.83e-3)" "unprognostic (6.11e-3)" "unprognostic (5.29e-2)" "validated prognostic unfavorable (3.71e-4)" "validated prognostic unfavorable (3.38e-7)" "unprognostic (1.29e-1)" "unprognostic (3.98e-2)" "unprognostic (5.64e-2)" "unprognostic (1.66e-1)" "unprognostic (4.83e-2)" "unprognostic (2.17e-1)" "unprognostic (1.75e-2)" "potential prognostic unfavorable (2.24e-4)" "unprognostic (1.08e-2)" "unprognostic (1.38e-2)" "unprognostic (1.58e-1)" "unprognostic (8.85e-2)" "unprognostic (1.05e-1)" "unprognostic (3.33e-1)" "unprognostic (9.78e-2)" "unprognostic (2.53e-1)" RPL17-C18orf32 ENSG00000215472 "RPL17-C18orf32 readthrough" 18 49481681-49492479 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 226.7" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 11.3;Early spermatids: 19.2;Hepatic stellate cells: 6.5;Late spermatids: 6.8;Tuft cells: 11.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA043724, HPA046385" Approved Supported "Endoplasmic reticulum,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 55: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 35 "Endoplasmic reticulum, Cytosol" "HPA043724: , HPA046385: " "unprognostic (1.19e-2)" "unprognostic (1.56e-2)" "unprognostic (6.34e-2)" "unprognostic (2.64e-2)" "potential prognostic unfavorable (6.95e-4)" "unprognostic (3.58e-1)" "unprognostic (5.55e-2)" "unprognostic (9.53e-2)" "unprognostic (5.59e-2)" "potential prognostic favorable (7.53e-8)" "unprognostic (6.49e-3)" "unprognostic (1.11e-3)" "unprognostic (2.58e-1)" "unprognostic (1.41e-1)" "unprognostic (4.35e-2)" "unprognostic (1.60e-1)" "unprognostic (4.25e-1)" "unprognostic (4.36e-2)" "unprognostic (2.20e-1)" "unprognostic (6.97e-2)" "unprognostic (3.79e-2)" "unprognostic (1.63e-2)" "unprognostic (1.85e-1)" "unprognostic (1.34e-2)" "unprognostic (7.79e-2)" "unprognostic (1.43e-1)" "unprognostic (2.80e-1)" "unprognostic (3.64e-1)" "unprognostic (1.35e-1)" RPL18 L18 ENSG00000063177 "Ribosomal protein L18" Q07020 19 48615328-48619184 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Diamond-Blackfan anemia, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 10031.4;Esophageal basal cells: 6988.2;Esophageal suprabasal cells: 8045.8;Extravillous trophoblasts: 6683.3" "Cell type enhanced" "Detected in all" "leukocyte: 560.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" HPA046572 Approved Supported "Nucleoli,Endoplasmic reticulum,Cytosol" NA NA 230000 "Cluster 18: Non-specific - Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 180 "Endoplasmic reticulum, Cytosol" Nucleoli "HPA046572: " "unprognostic (2.14e-2)" "unprognostic (6.20e-2)" "unprognostic (1.94e-1)" "unprognostic (1.57e-2)" "unprognostic (5.79e-2)" "unprognostic (2.58e-3)" "unprognostic (2.10e-2)" "unprognostic (1.05e-1)" "unprognostic (7.02e-2)" "unprognostic (1.19e-1)" "unprognostic (3.55e-2)" "unprognostic (2.10e-1)" "unprognostic (9.58e-3)" "validated prognostic unfavorable (3.61e-5)" "validated prognostic unfavorable (1.41e-5)" "unprognostic (3.36e-2)" "unprognostic (3.87e-2)" "unprognostic (7.73e-2)" "unprognostic (1.66e-1)" "unprognostic (7.23e-2)" "unprognostic (2.87e-1)" "unprognostic (9.68e-2)" "unprognostic (4.59e-2)" "unprognostic (1.67e-1)" "unprognostic (3.92e-1)" "unprognostic (2.36e-1)" "unprognostic (1.88e-1)" "unprognostic (2.11e-1)" "unprognostic (1.20e-1)" "unprognostic (5.19e-2)" "unprognostic (1.12e-1)" RPL18A L18A ENSG00000105640 "Ribosomal protein L18a" Q02543 19 17859910-17864153 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Decidual stromal cells: 9050.3;Esophageal basal cells: 8943.5;Esophageal suprabasal cells: 9700.7;Extravillous trophoblasts: 9623.0;Suprabasal keratinocytes: 7006.5" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 293.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055259 Approved Approved Nucleoplasm,Nucleoli,Cytosol No No 8200 "Cluster 18: Non-specific - Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 165 Nucleoli "Nucleoplasm, Cytosol" "HPA055259: " "unprognostic (5.49e-3)" "unprognostic (4.15e-2)" "unprognostic (1.06e-3)" "unprognostic (7.87e-3)" "unprognostic (2.00e-1)" "unprognostic (4.88e-3)" "unprognostic (2.43e-2)" "potential prognostic favorable (8.13e-5)" "unprognostic (2.19e-1)" "unprognostic (3.24e-1)" "unprognostic (1.22e-2)" "unprognostic (1.84e-2)" "unprognostic (4.88e-3)" "validated prognostic unfavorable (1.22e-4)" "validated prognostic unfavorable (1.73e-5)" "unprognostic (3.02e-3)" "unprognostic (8.36e-2)" "unprognostic (4.09e-2)" "unprognostic (3.29e-1)" "unprognostic (1.81e-2)" "unprognostic (2.03e-1)" "unprognostic (1.03e-1)" "unprognostic (4.34e-1)" "unprognostic (2.25e-1)" "unprognostic (3.54e-2)" "unprognostic (1.25e-1)" "unprognostic (6.57e-2)" "unprognostic (4.03e-1)" "unprognostic (9.55e-2)" "unprognostic (5.11e-2)" "unprognostic (1.57e-1)" RPL19 "DKFZp779D216, FLJ27452, L19, MGC71997" ENSG00000108298 "Ribosomal protein L19" P84098 17 39200283-39204840 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal basal cells: 9460.9;Esophageal suprabasal cells: 9959.7;Gastric progenitor cells: 14562.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043014, HPA051987" Approved Enhanced Nucleoli,Cytosol NA NA 47000 "Cluster 18: Non-specific - Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 27: Breast cancer - Unknown function" "Cluster 15: Non-specific - Protein processing" 421 "Nucleoli, Cytosol" "HPA043014: , HPA051987: " "unprognostic (3.39e-2)" "unprognostic (8.64e-2)" "unprognostic (2.08e-1)" "unprognostic (5.65e-2)" "unprognostic (1.39e-1)" "unprognostic (1.96e-1)" "unprognostic (4.23e-2)" "unprognostic (1.80e-2)" "unprognostic (5.86e-3)" "unprognostic (2.17e-3)" "unprognostic (1.24e-2)" "unprognostic (1.26e-1)" "unprognostic (3.75e-3)" "validated prognostic unfavorable (1.05e-4)" "validated prognostic unfavorable (1.24e-4)" "unprognostic (4.50e-2)" "unprognostic (4.87e-2)" "unprognostic (1.04e-1)" "unprognostic (1.89e-1)" "unprognostic (3.31e-3)" "unprognostic (1.04e-1)" "unprognostic (4.05e-2)" "unprognostic (2.31e-1)" "unprognostic (1.01e-1)" "potential prognostic favorable (8.11e-5)" "unprognostic (1.80e-2)" "unprognostic (3.32e-2)" "unprognostic (1.15e-1)" "unprognostic (1.79e-1)" "unprognostic (2.14e-2)" "unprognostic (4.49e-2)" RPL21 "DKFZp686C06101, FLJ27458, L21, MGC104274, MGC104275, MGC71252" ENSG00000122026 "Ribosomal protein L21" P46778 13 27251362-27256691 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal basal cells: 7381.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" HPA047252 Approved Supported "Nucleoli fibrillar center,Endoplasmic reticulum,Cytosol" NA NA 28000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 122 "Nucleoli fibrillar center, Endoplasmic reticulum, Cytosol" "HPA047252: " "unprognostic (5.10e-3)" "unprognostic (3.80e-2)" "unprognostic (1.31e-1)" "unprognostic (1.20e-2)" "unprognostic (4.25e-2)" "unprognostic (9.65e-2)" "unprognostic (6.14e-2)" "potential prognostic favorable (4.18e-4)" "unprognostic (7.74e-3)" "unprognostic (2.42e-2)" "unprognostic (1.89e-2)" "potential prognostic favorable (9.17e-6)" "unprognostic (1.21e-1)" "validated prognostic unfavorable (1.67e-4)" "validated prognostic unfavorable (1.16e-4)" "unprognostic (5.79e-2)" "unprognostic (3.45e-2)" "unprognostic (2.49e-1)" "unprognostic (5.75e-2)" "unprognostic (1.63e-3)" "unprognostic (2.13e-1)" "unprognostic (1.06e-1)" "unprognostic (1.34e-1)" "unprognostic (1.71e-1)" "unprognostic (3.18e-1)" "unprognostic (1.83e-1)" "unprognostic (8.59e-3)" "unprognostic (1.70e-1)" "unprognostic (3.60e-1)" "unprognostic (4.21e-2)" "unprognostic (8.04e-2)" RPL22 "EAP, L22" ENSG00000116251 "Ribosomal protein L22" P35268 1 6185020-6209389 "Cancer-related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Heparin-binding, Ribonucleoprotein, Ribosomal protein, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1138.9;Gastric chief cells: 988.3;Parietal cells: 746.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068294 Uncertain Nucleoplasm,Nucleoli NA NA 810000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 148 Nucleoli Nucleoplasm "HPA068294: " "unprognostic (5.65e-3)" "unprognostic (1.41e-2)" "unprognostic (9.61e-2)" "unprognostic (1.36e-2)" "unprognostic (2.26e-1)" "unprognostic (4.50e-2)" "unprognostic (1.41e-1)" "unprognostic (2.83e-2)" "unprognostic (3.89e-2)" "unprognostic (2.77e-3)" "potential prognostic favorable (2.14e-7)" "unprognostic (5.84e-2)" "unprognostic (1.13e-2)" "unprognostic (1.22e-2)" "potential prognostic unfavorable (1.47e-7)" "unprognostic (2.45e-2)" "unprognostic (3.39e-2)" "unprognostic (6.36e-2)" "unprognostic (4.73e-1)" "unprognostic (2.40e-1)" "unprognostic (5.15e-2)" "unprognostic (9.11e-2)" "unprognostic (1.04e-1)" "unprognostic (2.58e-1)" "unprognostic (3.78e-2)" "unprognostic (2.36e-2)" "unprognostic (1.83e-1)" "unprognostic (7.50e-2)" "unprognostic (2.27e-1)" "unprognostic (1.26e-1)" "unprognostic (4.45e-2)" RPL22L1 ENSG00000163584 "Ribosomal protein L22 like 1" Q6P5R6 3 170864875-170870208 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 457.7;Erythrocyte progenitors: 478.7;Esophageal basal cells: 806.6;Esophageal suprabasal cells: 693.9;Gastric progenitor cells: 542.1;Plasma cells: 452.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048060, HPA056207, HPA068294" Uncertain Approved "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 42: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 16 Nucleoli "Nucleoplasm, Nucleoli rim" "HPA048060: , HPA056207: , HPA068294: " "potential prognostic unfavorable (1.02e-4)" "unprognostic (2.97e-1)" "unprognostic (2.25e-2)" "unprognostic (1.81e-1)" "unprognostic (1.46e-2)" "unprognostic (1.53e-1)" "unprognostic (6.71e-2)" "unprognostic (9.59e-2)" "unprognostic (3.10e-2)" "unprognostic (1.03e-1)" "validated prognostic unfavorable (4.11e-9)" "validated prognostic unfavorable (1.76e-6)" "potential prognostic unfavorable (3.65e-4)" "unprognostic (6.07e-2)" "unprognostic (2.05e-1)" "unprognostic (3.00e-2)" "unprognostic (6.01e-3)" "unprognostic (8.77e-2)" "unprognostic (1.87e-1)" "unprognostic (4.60e-2)" "unprognostic (6.66e-3)" "unprognostic (2.45e-2)" "unprognostic (1.67e-2)" "unprognostic (1.09e-2)" "unprognostic (2.94e-1)" "unprognostic (2.41e-2)" "unprognostic (1.97e-1)" "unprognostic (2.49e-2)" "unprognostic (1.90e-1)" "unprognostic (1.22e-2)" "unprognostic (3.43e-2)" RPL23 "L23, rpL17" ENSG00000125691 "Ribosomal protein L23" P62829 17 38847860-38853764 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal suprabasal cells: 4035.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003373 Approved Supported Cytosol NA NA 120000 "Cluster 18: Non-specific - Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 127 Cytosol "HPA003373: " "unprognostic (2.23e-3)" "unprognostic (1.50e-1)" "unprognostic (2.59e-1)" "unprognostic (5.84e-2)" "unprognostic (7.15e-2)" "unprognostic (7.46e-2)" "unprognostic (1.56e-2)" "unprognostic (2.68e-2)" "potential prognostic unfavorable (7.40e-5)" "unprognostic (4.43e-2)" "unprognostic (7.84e-3)" "unprognostic (1.50e-1)" "unprognostic (1.57e-2)" "validated prognostic unfavorable (6.01e-5)" "validated prognostic unfavorable (2.64e-4)" "unprognostic (3.19e-1)" "unprognostic (1.43e-2)" "unprognostic (3.71e-2)" "unprognostic (9.58e-2)" "unprognostic (8.14e-3)" "unprognostic (4.40e-3)" "unprognostic (5.05e-2)" "unprognostic (1.43e-2)" "unprognostic (1.72e-1)" "unprognostic (5.49e-3)" "unprognostic (9.79e-3)" "unprognostic (1.97e-2)" "unprognostic (1.05e-2)" "unprognostic (1.78e-1)" "unprognostic (1.32e-2)" "unprognostic (1.18e-1)" RPL23A L23A ENSG00000198242 "Ribosomal protein L23a" P62750 17 28719985-28724359 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 6538.5;Esophageal basal cells: 6271.3;Esophageal suprabasal cells: 6872.5;Extravillous trophoblasts: 7437.5;Migrating cytotrophoblasts: 6254.0;Ovarian stromal cells: 5999.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051754, HPA077474" Approved Approved "Nucleoli fibrillar center,Endoplasmic reticulum,Cytosol" NA NA 270000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 300 "Nucleoli fibrillar center, Endoplasmic reticulum, Cytosol" "HPA051754: , HPA077474: " "unprognostic (2.49e-3)" "unprognostic (2.55e-1)" "unprognostic (6.86e-2)" "unprognostic (3.98e-2)" "unprognostic (1.22e-1)" "unprognostic (1.70e-1)" "unprognostic (1.18e-1)" "potential prognostic favorable (5.92e-5)" "unprognostic (1.54e-2)" "unprognostic (8.14e-3)" "unprognostic (9.07e-3)" "unprognostic (1.40e-1)" "potential prognostic unfavorable (2.17e-4)" "validated prognostic unfavorable (1.03e-5)" "validated prognostic unfavorable (3.60e-6)" "unprognostic (7.56e-2)" "unprognostic (4.15e-3)" "unprognostic (2.30e-3)" "unprognostic (1.76e-1)" "unprognostic (1.63e-2)" "unprognostic (2.86e-3)" "unprognostic (4.37e-1)" "unprognostic (4.36e-1)" "unprognostic (9.49e-2)" "unprognostic (2.93e-1)" "unprognostic (3.49e-3)" "unprognostic (3.73e-1)" "unprognostic (5.18e-3)" "unprognostic (2.64e-1)" "unprognostic (1.98e-1)" "unprognostic (1.08e-1)" RPL24 L24 ENSG00000114391 "Ribosomal protein L24" P83731 3 101681091-101686733 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 5244.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051653 Approved Enhanced "Endoplasmic reticulum,Cytosol" NA NA 30000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 133 "Endoplasmic reticulum, Cytosol" "HPA051653: " "unprognostic (4.96e-3)" "unprognostic (1.49e-1)" "unprognostic (4.03e-2)" "potential prognostic favorable (2.33e-4)" "unprognostic (6.68e-2)" "unprognostic (6.72e-2)" "unprognostic (9.14e-2)" "unprognostic (4.94e-2)" "unprognostic (1.33e-2)" "unprognostic (3.39e-1)" "unprognostic (9.65e-2)" "unprognostic (1.68e-2)" "unprognostic (2.67e-2)" "validated prognostic unfavorable (1.91e-4)" "validated prognostic unfavorable (1.51e-4)" "unprognostic (1.56e-1)" "unprognostic (4.98e-3)" "unprognostic (1.13e-1)" "unprognostic (2.36e-2)" "unprognostic (9.54e-3)" "unprognostic (7.66e-3)" "unprognostic (8.98e-3)" "unprognostic (3.32e-2)" "unprognostic (8.30e-2)" "unprognostic (1.70e-2)" "unprognostic (2.82e-1)" "unprognostic (1.53e-1)" "unprognostic (8.00e-3)" "unprognostic (3.35e-1)" "unprognostic (3.26e-2)" "unprognostic (8.68e-2)" RPL26 L26 ENSG00000161970 "Ribosomal protein L26" P61254 17 8377516-8383213 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Diamond-Blackfan anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 5733.7;Enteric stem cells: 6397.2;Epididymal efferent duct absorptive cells: 6124.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030449, CAB037301" Supported Approved "Nucleoli,Endoplasmic reticulum,Cytosol" NA NA "Cluster 18: Non-specific - Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 65 "Endoplasmic reticulum, Cytosol" Nucleoli "CAB037301: , HPA030449: " "unprognostic (1.83e-1)" "unprognostic (4.14e-2)" "unprognostic (9.78e-3)" "unprognostic (2.65e-1)" "unprognostic (3.59e-2)" "unprognostic (4.91e-2)" "unprognostic (2.20e-2)" "unprognostic (7.93e-2)" "unprognostic (7.45e-2)" "unprognostic (5.83e-2)" "potential prognostic favorable (1.87e-5)" "unprognostic (3.35e-1)" "unprognostic (1.03e-1)" "unprognostic (7.12e-2)" "unprognostic (9.08e-2)" "unprognostic (9.85e-3)" "unprognostic (7.10e-2)" "unprognostic (2.10e-2)" "unprognostic (6.60e-2)" "unprognostic (7.35e-2)" "unprognostic (4.70e-2)" "unprognostic (1.13e-1)" "unprognostic (4.78e-2)" "unprognostic (7.31e-2)" "unprognostic (3.91e-2)" "unprognostic (9.30e-3)" "unprognostic (4.66e-3)" "unprognostic (1.08e-1)" "unprognostic (1.71e-1)" "unprognostic (7.99e-2)" "unprognostic (8.10e-2)" RPL26L1 RPL26P1 ENSG00000037241 "Ribosomal protein L26 like 1" Q9UNX3 5 172958729-172969771 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 187.9;Early spermatids: 333.6;Late primary spermatocytes: 611.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" HPA030449 Approved Approved "Nucleoli,Endoplasmic reticulum,Cytosol" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 14: Neurons - Synaptic function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 155 "Endoplasmic reticulum, Cytosol" Nucleoli "HPA030449: " "potential prognostic unfavorable (3.03e-4)" "unprognostic (4.65e-2)" "unprognostic (6.06e-2)" "unprognostic (3.89e-2)" "unprognostic (4.42e-2)" "unprognostic (3.63e-3)" "unprognostic (1.46e-1)" "unprognostic (7.21e-2)" "potential prognostic unfavorable (5.09e-4)" "unprognostic (1.68e-2)" "unprognostic (1.28e-3)" "potential prognostic unfavorable (8.83e-5)" "unprognostic (2.90e-1)" "validated prognostic unfavorable (4.19e-4)" "validated prognostic unfavorable (6.11e-4)" "unprognostic (4.79e-2)" "unprognostic (2.31e-1)" "unprognostic (2.18e-2)" "unprognostic (1.77e-1)" "unprognostic (1.28e-2)" "unprognostic (9.72e-3)" "unprognostic (1.85e-1)" "unprognostic (2.16e-2)" "unprognostic (9.95e-2)" "unprognostic (1.65e-1)" "unprognostic (2.33e-1)" "unprognostic (3.98e-1)" "unprognostic (1.55e-1)" "unprognostic (4.22e-1)" "unprognostic (3.46e-1)" "unprognostic (8.54e-2)" RPL27 L27 ENSG00000131469 "Ribosomal protein L27" P61353 17 42998273-43002959 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Cancer-related genes, Diamond-Blackfan anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 3819.3;Esophageal basal cells: 4678.8;Esophageal suprabasal cells: 5693.3;Extravillous trophoblasts: 4444.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002649 Approved Enhanced Nucleoplasm,Nucleoli NA NA 96000 "Cluster 34: B-cells - Unknown function" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 129 Nucleoli Nucleoplasm "HPA002649: " "unprognostic (7.43e-3)" "unprognostic (4.83e-2)" "unprognostic (1.49e-1)" "unprognostic (8.76e-3)" "unprognostic (1.95e-1)" "unprognostic (3.29e-1)" "unprognostic (1.42e-1)" "unprognostic (2.30e-2)" "unprognostic (1.94e-2)" "unprognostic (5.25e-2)" "unprognostic (1.43e-3)" "unprognostic (1.24e-1)" "unprognostic (4.26e-2)" "validated prognostic unfavorable (3.65e-5)" "validated prognostic unfavorable (1.23e-6)" "unprognostic (9.43e-2)" "unprognostic (1.02e-2)" "unprognostic (5.36e-3)" "unprognostic (1.41e-1)" "unprognostic (3.23e-1)" "unprognostic (1.37e-2)" "unprognostic (2.21e-3)" "unprognostic (1.63e-1)" "unprognostic (1.38e-1)" "unprognostic (2.28e-2)" "unprognostic (1.42e-1)" "unprognostic (2.80e-2)" "unprognostic (2.74e-2)" "unprognostic (1.84e-1)" "unprognostic (2.68e-2)" "unprognostic (2.50e-1)" RPL27A L27A ENSG00000166441 "Ribosomal protein L27a" P46776 11 8682788-8714759 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Decidual stromal cells: 7386.3;Esophageal apical cells: 6999.6;Esophageal basal cells: 7317.0;Esophageal suprabasal cells: 9451.3;Extravillous trophoblasts: 8618.1;Migrating cytotrophoblasts: 7075.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "HPA060776, HPA063379" Supported Enhanced "Endoplasmic reticulum,Cytosol" NA NA 33000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 123 "Endoplasmic reticulum, Cytosol" "HPA060776: , HPA063379: " "unprognostic (2.10e-3)" "potential prognostic favorable (1.96e-4)" "unprognostic (3.24e-1)" "unprognostic (1.11e-1)" "unprognostic (1.95e-1)" "unprognostic (1.26e-2)" "unprognostic (1.13e-1)" "unprognostic (1.15e-1)" "unprognostic (4.32e-2)" "unprognostic (2.99e-1)" "potential prognostic unfavorable (2.80e-5)" "unprognostic (1.37e-1)" "unprognostic (1.21e-2)" "validated prognostic unfavorable (9.54e-5)" "validated prognostic unfavorable (3.21e-4)" "unprognostic (9.65e-2)" "unprognostic (3.43e-3)" "unprognostic (1.23e-1)" "unprognostic (4.69e-2)" "unprognostic (5.13e-2)" "unprognostic (1.37e-1)" "unprognostic (1.39e-1)" "unprognostic (2.42e-1)" "unprognostic (4.56e-1)" "unprognostic (1.29e-1)" "unprognostic (5.10e-2)" "unprognostic (1.44e-1)" "unprognostic (4.47e-2)" "unprognostic (1.67e-1)" "unprognostic (5.71e-2)" "unprognostic (2.19e-2)" RPL28 "FLJ43307, L28" ENSG00000108107 "Ribosomal protein L28" P46779 19 55385932-55403250 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 15120.7;Esophageal suprabasal cells: 11054.1" "Cell type enhanced" "Detected in all" "leukocyte: 980.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050459 Approved Supported "Endoplasmic reticulum,Cytosol" NA NA 22000 "Cluster 18: Non-specific - Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 135 "Endoplasmic reticulum, Cytosol" "HPA050459: " "unprognostic (2.15e-1)" "unprognostic (1.01e-2)" "unprognostic (4.52e-1)" "unprognostic (1.75e-1)" "unprognostic (7.59e-2)" "potential prognostic unfavorable (8.94e-5)" "unprognostic (1.18e-1)" "unprognostic (4.29e-2)" "unprognostic (4.96e-3)" "unprognostic (6.54e-2)" "potential prognostic unfavorable (2.67e-4)" "unprognostic (8.41e-2)" "potential prognostic unfavorable (7.26e-4)" "unprognostic (1.13e-3)" "unprognostic (1.94e-3)" "unprognostic (4.78e-2)" "unprognostic (2.82e-3)" "unprognostic (1.72e-1)" "unprognostic (5.74e-3)" "unprognostic (1.43e-1)" "unprognostic (1.19e-1)" "unprognostic (3.15e-1)" "unprognostic (6.72e-2)" "unprognostic (2.00e-1)" "unprognostic (8.85e-2)" "unprognostic (1.63e-1)" "unprognostic (3.90e-1)" "unprognostic (2.61e-1)" "unprognostic (1.14e-1)" "unprognostic (1.69e-1)" "unprognostic (1.20e-1)" RPL29 "HIP, HUMRPL29, L29, RPL29P10" ENSG00000162244 "Ribosomal protein L29" P47914 3 51993522-51995895 "Predicted intracellular proteins, Ribosomal proteins" "Heparin-binding, Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 7729.3;Esophageal apical cells: 6930.6;Esophageal basal cells: 8164.2;Esophageal suprabasal cells: 9426.7;Late spermatids: 6589.3;Pancreatic acinar cells: 7438.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" HPA069064 Approved Supported "Nucleoli,Endoplasmic reticulum,Cytosol" NA NA "Cluster 18: Non-specific - Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 59 "Nucleoli, Endoplasmic reticulum, Cytosol" "HPA069064: " "unprognostic (6.09e-3)" "potential prognostic favorable (6.22e-4)" "unprognostic (1.34e-1)" "unprognostic (2.26e-3)" "unprognostic (2.99e-1)" "unprognostic (1.13e-1)" "unprognostic (3.26e-2)" "potential prognostic favorable (5.38e-5)" "unprognostic (6.29e-3)" "unprognostic (2.55e-1)" "unprognostic (8.60e-3)" "unprognostic (9.31e-2)" "unprognostic (1.86e-2)" "validated prognostic unfavorable (9.91e-5)" "validated prognostic unfavorable (6.77e-6)" "unprognostic (2.22e-1)" "unprognostic (2.65e-3)" "unprognostic (2.20e-2)" "unprognostic (8.51e-2)" "unprognostic (5.06e-2)" "unprognostic (4.60e-1)" "unprognostic (9.45e-3)" "unprognostic (1.61e-1)" "unprognostic (5.41e-2)" "unprognostic (3.04e-2)" "unprognostic (4.39e-2)" "unprognostic (5.38e-2)" "unprognostic (7.16e-2)" "unprognostic (2.17e-1)" "unprognostic (2.88e-1)" "unprognostic (8.91e-2)" RPL3 L3 ENSG00000100316 "Ribosomal protein L3" P39023 22 39312882-39320389 "Essential proteins, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Breast secretory cells: 10257.5;Decidual stromal cells: 13457.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003365, HPA055361" Uncertain Supported Nucleoli,Cytosol NA NA 1400000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 348 "Nucleoli, Cytosol" "HPA003365: , HPA055361: " "unprognostic (1.16e-2)" "unprognostic (1.10e-3)" "unprognostic (1.28e-1)" "unprognostic (5.06e-2)" "unprognostic (2.68e-1)" "unprognostic (6.50e-2)" "unprognostic (2.96e-3)" "unprognostic (2.54e-3)" "unprognostic (5.02e-2)" "unprognostic (2.05e-1)" "unprognostic (1.25e-2)" "unprognostic (5.58e-3)" "unprognostic (4.60e-2)" "unprognostic (1.99e-2)" "unprognostic (1.33e-3)" "unprognostic (1.36e-1)" "unprognostic (1.01e-1)" "unprognostic (1.83e-1)" "unprognostic (4.64e-1)" "unprognostic (2.52e-3)" "unprognostic (2.17e-2)" "unprognostic (2.54e-2)" "unprognostic (8.33e-3)" "unprognostic (7.53e-2)" "unprognostic (5.36e-3)" "unprognostic (2.99e-1)" "unprognostic (1.31e-1)" "unprognostic (1.22e-1)" "unprognostic (4.02e-1)" "unprognostic (8.87e-2)" "unprognostic (5.20e-2)" RPL30 L30 ENSG00000156482 "Ribosomal protein L30" P62888 8 98024851-98046469 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002651 Approved Approved "Endoplasmic reticulum,Cytosol" NA NA 140000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 208 "Endoplasmic reticulum, Cytosol" "HPA002651: " "unprognostic (1.38e-2)" "unprognostic (1.70e-1)" "unprognostic (2.80e-1)" "unprognostic (8.41e-3)" "unprognostic (2.30e-1)" "unprognostic (4.38e-2)" "unprognostic (4.69e-3)" "unprognostic (1.82e-2)" "unprognostic (5.38e-3)" "potential prognostic unfavorable (3.34e-4)" "unprognostic (6.58e-3)" "unprognostic (3.13e-1)" "potential prognostic unfavorable (2.24e-7)" "unprognostic (2.00e-2)" "potential prognostic unfavorable (4.26e-4)" "unprognostic (2.41e-2)" "unprognostic (5.15e-2)" "unprognostic (3.49e-1)" "unprognostic (1.40e-1)" "unprognostic (1.90e-1)" "unprognostic (4.83e-2)" "unprognostic (8.48e-3)" "unprognostic (7.05e-2)" "unprognostic (1.16e-1)" "unprognostic (2.64e-1)" "unprognostic (8.20e-2)" "unprognostic (2.87e-1)" "unprognostic (1.76e-1)" "unprognostic (3.08e-1)" "unprognostic (1.39e-3)" "unprognostic (7.24e-2)" RPL31 L31 ENSG00000071082 "Ribosomal protein L31" P62899 2 101002229-101024032 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 7456.0;Enteric stem cells: 5016.4;Epididymal efferent duct absorptive cells: 5581.3;Esophageal apical cells: 5695.6;Esophageal basal cells: 5392.4;Esophageal suprabasal cells: 6392.6;Extravillous trophoblasts: 5671.1;Migrating cytotrophoblasts: 5411.3;Ovarian stromal cells: 6950.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" HPA072263 Approved NA NA 110000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 367 "HPA072263: " "unprognostic (1.59e-2)" "unprognostic (9.46e-3)" "unprognostic (8.31e-2)" "unprognostic (5.39e-3)" "unprognostic (1.96e-2)" "unprognostic (3.38e-1)" "unprognostic (9.84e-2)" "unprognostic (4.04e-2)" "unprognostic (1.00e-2)" "unprognostic (3.14e-1)" "potential prognostic favorable (3.97e-4)" "unprognostic (1.11e-1)" "potential prognostic unfavorable (3.54e-4)" "unprognostic (2.12e-3)" "potential prognostic unfavorable (5.88e-5)" "unprognostic (4.90e-2)" "unprognostic (1.70e-2)" "unprognostic (1.19e-2)" "unprognostic (9.41e-2)" "unprognostic (5.91e-2)" "unprognostic (8.01e-3)" "unprognostic (1.02e-1)" "unprognostic (1.21e-1)" "unprognostic (8.67e-2)" "unprognostic (7.73e-2)" "unprognostic (2.11e-1)" "unprognostic (6.41e-3)" "unprognostic (5.31e-3)" "unprognostic (1.82e-1)" "unprognostic (1.19e-1)" "unprognostic (1.24e-1)" RPL32 L32 ENSG00000144713 "Ribosomal protein L32" P62910 3 12834485-12841582 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Decidual stromal cells: 11509.6;Esophageal basal cells: 11301.9;Esophageal suprabasal cells: 12675.3;Gastric progenitor cells: 10898.1;Late spermatids: 11651.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047501, HPA051994" Enhanced Approved "Endoplasmic reticulum,Cytosol" NA NA 16000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 113 "Endoplasmic reticulum, Cytosol" "HPA047501: , HPA051994: " "unprognostic (1.57e-3)" "unprognostic (1.28e-1)" "unprognostic (1.87e-1)" "unprognostic (1.14e-2)" "unprognostic (5.05e-1)" "unprognostic (2.16e-2)" "unprognostic (1.33e-2)" "unprognostic (7.64e-2)" "unprognostic (1.42e-1)" "unprognostic (2.71e-2)" "unprognostic (5.72e-2)" "unprognostic (1.35e-1)" "unprognostic (2.91e-2)" "validated prognostic unfavorable (6.49e-5)" "validated prognostic unfavorable (1.62e-4)" "unprognostic (6.74e-2)" "unprognostic (5.09e-3)" "unprognostic (2.41e-3)" "unprognostic (5.06e-2)" "unprognostic (6.29e-3)" "unprognostic (2.95e-2)" "unprognostic (1.41e-1)" "unprognostic (4.49e-1)" "unprognostic (7.12e-2)" "unprognostic (4.17e-2)" "unprognostic (2.20e-1)" "unprognostic (9.10e-2)" "unprognostic (2.79e-1)" "unprognostic (2.07e-1)" "unprognostic (1.28e-1)" "unprognostic (9.67e-2)" RPL34 L34 ENSG00000109475 "Ribosomal protein L34" P49207 4 108620569-108630412 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 12410.3;Ovarian stromal cells: 11718.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035139, HPA076722" Uncertain Supported "Nucleoli,Endoplasmic reticulum,Cytosol" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 81 "Endoplasmic reticulum, Cytosol" Nucleoli "HPA035139: , HPA076722: " "unprognostic (1.04e-2)" "unprognostic (2.56e-2)" "unprognostic (5.84e-2)" "unprognostic (1.96e-3)" "unprognostic (7.67e-2)" "unprognostic (1.17e-1)" "unprognostic (1.37e-1)" "unprognostic (3.90e-2)" "unprognostic (3.71e-2)" "unprognostic (5.46e-2)" "unprognostic (9.14e-3)" "unprognostic (3.54e-3)" "unprognostic (7.97e-2)" "unprognostic (2.92e-1)" "unprognostic (1.13e-2)" "unprognostic (3.13e-1)" "unprognostic (1.78e-2)" "unprognostic (2.77e-1)" "unprognostic (2.17e-2)" "unprognostic (1.73e-1)" "unprognostic (1.63e-2)" "unprognostic (1.84e-1)" "unprognostic (8.59e-2)" "unprognostic (1.90e-1)" "unprognostic (5.53e-3)" "unprognostic (2.24e-1)" "unprognostic (1.34e-1)" "unprognostic (1.30e-1)" "unprognostic (1.95e-1)" "unprognostic (1.86e-1)" "unprognostic (3.13e-2)" RPL35 L35 ENSG00000136942 "Ribosomal protein L35" P42766 9 124857880-124861981 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Diamond-Blackfan anemia, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 6504.0;Esophageal suprabasal cells: 7610.5;Late spermatids: 9439.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006047 Approved Approved "Endoplasmic reticulum,Cytosol" NA NA 25000 "Cluster 18: Non-specific - Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 343 "Endoplasmic reticulum, Cytosol" "HPA006047: " "potential prognostic unfavorable (2.66e-4)" "unprognostic (5.78e-2)" "unprognostic (4.11e-1)" "unprognostic (2.49e-3)" "unprognostic (2.32e-2)" "potential prognostic unfavorable (1.07e-4)" "unprognostic (3.54e-2)" "unprognostic (7.78e-2)" "unprognostic (2.17e-2)" "unprognostic (3.80e-1)" "unprognostic (5.42e-3)" "unprognostic (1.32e-2)" "unprognostic (2.32e-2)" "validated prognostic unfavorable (9.57e-5)" "validated prognostic unfavorable (1.06e-5)" "unprognostic (9.99e-3)" "potential prognostic unfavorable (9.32e-4)" "unprognostic (6.85e-2)" "unprognostic (1.10e-1)" "unprognostic (4.75e-2)" "unprognostic (2.06e-1)" "unprognostic (2.44e-1)" "unprognostic (2.68e-1)" "unprognostic (1.11e-1)" "unprognostic (1.72e-1)" "unprognostic (1.63e-1)" "unprognostic (5.21e-2)" "unprognostic (3.68e-1)" "unprognostic (1.45e-1)" "unprognostic (1.41e-1)" "unprognostic (8.19e-2)" RPL35A "eL33, GIG33, L35A" ENSG00000182899 "Ribosomal protein L35a" P18077 3 197950190-197956610 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein, RNA-binding, tRNA-binding" "Diamond-Blackfan anemia, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Decidual stromal cells: 7059.6;Ovarian stromal cells: 6974.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" NA NA 17000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 56 "potential prognostic unfavorable (9.69e-4)" "unprognostic (2.49e-1)" "unprognostic (2.90e-1)" "potential prognostic favorable (1.84e-4)" "unprognostic (3.64e-2)" "unprognostic (1.01e-1)" "unprognostic (9.79e-2)" "unprognostic (1.42e-1)" "unprognostic (8.24e-3)" "unprognostic (6.32e-2)" "unprognostic (1.09e-1)" "unprognostic (1.03e-2)" "potential prognostic unfavorable (2.33e-4)" "validated prognostic unfavorable (1.82e-5)" "validated prognostic unfavorable (1.09e-7)" "unprognostic (4.79e-2)" "potential prognostic unfavorable (4.53e-4)" "unprognostic (2.57e-2)" "unprognostic (2.47e-1)" "unprognostic (1.26e-1)" "unprognostic (6.88e-3)" "unprognostic (3.90e-3)" "unprognostic (6.33e-2)" "unprognostic (1.69e-2)" "unprognostic (3.14e-2)" "unprognostic (2.78e-1)" "unprognostic (1.19e-1)" "unprognostic (2.38e-2)" "unprognostic (1.64e-1)" "unprognostic (1.16e-1)" "unprognostic (1.95e-1)" RPL36 "DKFZp566B023, L36" ENSG00000130255 "Ribosomal protein L36" Q9Y3U8 19 5674947-5691875 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047153 Supported Supported Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 138 Cytosol "HPA047153: " "unprognostic (2.03e-2)" "unprognostic (4.55e-2)" "unprognostic (1.08e-1)" "unprognostic (4.51e-3)" "unprognostic (6.68e-2)" "unprognostic (1.18e-1)" "unprognostic (9.03e-2)" "unprognostic (3.08e-1)" "unprognostic (2.19e-1)" "unprognostic (7.70e-2)" "unprognostic (3.21e-2)" "unprognostic (6.77e-2)" "unprognostic (6.18e-3)" "unprognostic (2.02e-3)" "potential prognostic unfavorable (4.98e-6)" "unprognostic (2.46e-1)" "unprognostic (1.79e-3)" "unprognostic (3.07e-2)" "unprognostic (4.65e-1)" "unprognostic (2.77e-1)" "unprognostic (3.07e-2)" "unprognostic (9.35e-2)" "unprognostic (2.29e-1)" "unprognostic (1.05e-1)" "unprognostic (1.58e-1)" "unprognostic (2.21e-1)" "unprognostic (2.59e-1)" "unprognostic (1.00e-1)" "unprognostic (2.69e-1)" "unprognostic (2.77e-1)" "unprognostic (1.80e-2)" RPL36A "L36A, RPL44" ENSG00000241343 "Ribosomal protein L36a" P83881 X 101390824-101396155 "Essential proteins, Metabolic proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enteric stem cells: 2482.5;Enteric transient amplifying cells: 2165.0;Epididymal basal cells: 1286.6;Epididymal efferent duct absorptive cells: 1777.4;Gastric chief cells: 1408.7;Goblet cells: 1513.4;Paneth cells: 1972.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063979, HPA077586" Uncertain Supported "Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 13 "Endoplasmic reticulum, Cytosol" "Plasma membrane" "HPA063979: , HPA077586: " "unprognostic (6.81e-3)" "unprognostic (8.06e-3)" "unprognostic (5.59e-2)" "unprognostic (1.72e-3)" "unprognostic (4.77e-2)" "unprognostic (1.11e-1)" "unprognostic (1.17e-1)" "potential prognostic favorable (1.46e-4)" "unprognostic (3.54e-3)" "unprognostic (3.73e-1)" "potential prognostic unfavorable (7.32e-5)" "unprognostic (1.30e-2)" "unprognostic (2.84e-3)" "unprognostic (1.31e-3)" "potential prognostic unfavorable (1.42e-5)" "unprognostic (6.55e-2)" "potential prognostic unfavorable (8.84e-4)" "unprognostic (7.39e-3)" "unprognostic (3.21e-2)" "unprognostic (6.52e-2)" "unprognostic (1.32e-1)" "unprognostic (9.55e-3)" "unprognostic (1.06e-1)" "unprognostic (3.45e-2)" "unprognostic (8.72e-2)" "unprognostic (4.69e-2)" "unprognostic (1.03e-1)" "unprognostic (1.94e-2)" "unprognostic (4.99e-1)" "unprognostic (4.38e-2)" "unprognostic (2.12e-1)" RPL36A-HNRNPH2 ENSG00000257529 "RPL36A-HNRNPH2 readthrough" X 101391011-101412297 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Epicardial cells: 213.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA077586 Approved "Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA "Cluster 18: Non-specific - Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 27: Non-specific - Mixed function" "Cluster 25: Non-specific - Ribosome" "Cluster 67: Plasma cells - Plasma cell differentiation" 1 "Endoplasmic reticulum, Cytosol" "Plasma membrane" "HPA077586: " "unprognostic (3.42e-2)" "unprognostic (1.75e-1)" "unprognostic (1.49e-2)" "unprognostic (3.17e-2)" "unprognostic (6.54e-2)" "potential prognostic favorable (5.85e-4)" "potential prognostic unfavorable (2.51e-4)" "unprognostic (2.33e-1)" "unprognostic (1.81e-2)" "unprognostic (8.04e-2)" "potential prognostic unfavorable (1.48e-7)" "unprognostic (3.01e-2)" "unprognostic (2.14e-2)" "potential prognostic unfavorable (1.78e-4)" "potential prognostic favorable (4.36e-4)" "unprognostic (1.96e-1)" "unprognostic (3.23e-1)" "unprognostic (3.92e-2)" "unprognostic (1.45e-2)" "unprognostic (1.53e-2)" "unprognostic (1.36e-2)" "unprognostic (2.35e-1)" "unprognostic (1.83e-1)" "unprognostic (2.67e-1)" "unprognostic (1.82e-1)" "unprognostic (4.85e-2)" "unprognostic (6.01e-2)" RPL36AL "RPL36A, RPL36AP42" ENSG00000165502 "Ribosomal protein L36a like" Q969Q0 14 49618530-49620626 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 2928.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Not detected" "Not detected" HPA077586 Approved "Endoplasmic reticulum,Plasma membrane,Cytosol" NA Yes "Cluster 3: Non-specific - Nuclear processes" "Cluster 54: Non-specific - Ribosome" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 15: Non-specific - Protein processing" 126 "Endoplasmic reticulum, Cytosol" "Plasma membrane" "HPA077586: " "unprognostic (2.24e-2)" "unprognostic (1.11e-2)" "unprognostic (4.45e-1)" "potential prognostic favorable (6.22e-4)" "unprognostic (3.79e-2)" "unprognostic (8.06e-2)" "unprognostic (1.97e-1)" "unprognostic (7.59e-2)" "unprognostic (3.88e-3)" "unprognostic (1.61e-1)" "potential prognostic favorable (4.78e-6)" "unprognostic (9.71e-3)" "unprognostic (7.83e-2)" "unprognostic (1.05e-2)" "unprognostic (3.08e-2)" "unprognostic (7.04e-3)" "unprognostic (1.45e-2)" "unprognostic (1.89e-2)" "unprognostic (1.84e-1)" "unprognostic (1.54e-1)" "unprognostic (1.34e-1)" "unprognostic (1.84e-1)" "unprognostic (5.15e-2)" "unprognostic (1.73e-1)" "unprognostic (2.10e-2)" "potential prognostic unfavorable (3.48e-4)" "unprognostic (1.21e-1)" "unprognostic (1.56e-1)" "unprognostic (1.60e-1)" "unprognostic (1.81e-3)" "unprognostic (1.20e-2)" RPL37 L37 ENSG00000145592 "Ribosomal protein L37" P61927 5 40825262-40835222 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" NA NA "Cluster 18: Non-specific - Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 6 "unprognostic (1.64e-2)" "unprognostic (8.79e-2)" "unprognostic (1.50e-1)" "unprognostic (1.85e-3)" "unprognostic (4.96e-3)" "unprognostic (1.87e-2)" "unprognostic (1.97e-1)" "potential prognostic favorable (8.01e-4)" "unprognostic (5.03e-2)" "unprognostic (1.12e-1)" "unprognostic (2.83e-1)" "unprognostic (2.47e-1)" "potential prognostic unfavorable (1.03e-5)" "unprognostic (2.26e-2)" "unprognostic (2.25e-3)" "unprognostic (1.40e-1)" "unprognostic (4.27e-3)" "unprognostic (1.18e-1)" "unprognostic (2.13e-1)" "unprognostic (3.17e-1)" "unprognostic (3.26e-2)" "unprognostic (1.03e-2)" "unprognostic (5.48e-2)" "unprognostic (1.03e-1)" "unprognostic (3.05e-2)" "unprognostic (1.58e-1)" "unprognostic (1.01e-1)" "unprognostic (1.07e-1)" "unprognostic (2.32e-1)" "unprognostic (6.89e-2)" "unprognostic (3.95e-1)" RPL37A L37A ENSG00000197756 "Ribosomal protein L37a" P61513 2 216498825-216579180 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 10328.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA065327 Approved Approved "Endoplasmic reticulum,Cytosol" NA NA 26000 "Cluster 18: Non-specific - Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 145 "Endoplasmic reticulum, Cytosol" "HPA065327: " "unprognostic (3.62e-1)" "unprognostic (4.49e-2)" "unprognostic (1.07e-2)" "unprognostic (8.77e-3)" "unprognostic (2.13e-1)" "potential prognostic unfavorable (4.61e-4)" "unprognostic (1.92e-2)" "unprognostic (1.33e-3)" "unprognostic (1.44e-1)" "unprognostic (2.47e-1)" "unprognostic (5.01e-3)" "unprognostic (3.74e-2)" "unprognostic (1.79e-3)" "unprognostic (1.28e-2)" "potential prognostic unfavorable (1.60e-6)" "unprognostic (4.08e-2)" "unprognostic (1.07e-2)" "unprognostic (5.31e-2)" "unprognostic (5.39e-2)" "unprognostic (5.92e-2)" "unprognostic (1.21e-1)" "unprognostic (5.66e-2)" "unprognostic (1.61e-1)" "unprognostic (2.17e-1)" "unprognostic (4.35e-3)" "unprognostic (3.78e-2)" "unprognostic (1.28e-1)" "unprognostic (1.51e-1)" "unprognostic (1.14e-1)" "unprognostic (1.09e-1)" "unprognostic (7.79e-2)" RPL38 L38 ENSG00000172809 "Ribosomal protein L38" P63173 17 74203582-74210655 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 4975.3;Ovarian stromal cells: 4639.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052543 Approved Supported "Endoplasmic reticulum,Cytosol" NA NA 75000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 100 "Endoplasmic reticulum, Cytosol" "HPA052543: " "unprognostic (1.95e-2)" "unprognostic (4.29e-3)" "unprognostic (2.24e-1)" "unprognostic (5.47e-2)" "unprognostic (2.43e-1)" "unprognostic (1.37e-1)" "unprognostic (5.59e-2)" "unprognostic (6.73e-2)" "potential prognostic unfavorable (2.88e-4)" "unprognostic (6.90e-2)" "unprognostic (4.28e-2)" "unprognostic (9.19e-2)" "potential prognostic unfavorable (7.95e-4)" "validated prognostic unfavorable (2.71e-4)" "validated prognostic unfavorable (3.27e-4)" "unprognostic (1.21e-3)" "unprognostic (5.79e-3)" "unprognostic (6.69e-2)" "unprognostic (2.20e-1)" "unprognostic (5.09e-2)" "unprognostic (1.01e-1)" "unprognostic (6.45e-2)" "unprognostic (3.28e-1)" "unprognostic (1.04e-1)" "unprognostic (2.62e-3)" "unprognostic (1.26e-1)" "unprognostic (2.37e-2)" "unprognostic (2.71e-1)" "unprognostic (1.69e-1)" "unprognostic (1.69e-1)" "unprognostic (2.27e-1)" RPL39 "L39, RPL39P42" ENSG00000198918 "Ribosomal protein L39" P62891 X 119786504-119791630 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast secretory cells: 2032.9;Enteric stem cells: 1878.5;Gastric chief cells: 4017.7;Mucous neck cells: 2689.5;Parietal cells: 3732.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA047105 Uncertain NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 28 "HPA047105: " "unprognostic (6.85e-3)" "unprognostic (2.51e-1)" "unprognostic (4.39e-1)" "potential prognostic favorable (1.63e-4)" "unprognostic (1.32e-1)" "unprognostic (1.05e-1)" "unprognostic (1.05e-1)" "unprognostic (4.23e-3)" "potential prognostic unfavorable (3.29e-4)" "unprognostic (5.41e-2)" "unprognostic (2.58e-3)" "unprognostic (3.67e-2)" "potential prognostic unfavorable (4.56e-6)" "unprognostic (2.94e-3)" "potential prognostic unfavorable (2.44e-4)" "unprognostic (2.33e-1)" "unprognostic (4.62e-3)" "unprognostic (7.55e-3)" "unprognostic (1.69e-1)" "unprognostic (2.60e-1)" "unprognostic (2.25e-1)" "unprognostic (5.79e-3)" "unprognostic (2.15e-1)" "unprognostic (1.56e-1)" "unprognostic (1.86e-1)" "unprognostic (2.49e-1)" "unprognostic (6.60e-2)" "unprognostic (1.30e-1)" "unprognostic (1.19e-1)" "unprognostic (2.20e-1)" "unprognostic (9.83e-2)" RPL39L RPL39L1 ENSG00000163923 "Ribosomal protein L39 like" Q96EH5 3 187120948-187180908 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "testis: 210.4" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 134.3;Early primary spermatocytes: 411.7;Early spermatids: 414.1;Late primary spermatocytes: 1481.7;Late spermatids: 268.6;Oocytes: 354.6" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 189.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" HPA047105 Approved NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 67: Testis - Mixed function" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 63: Non-specific - Protein processing" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 1 "HPA047105: " "unprognostic (6.32e-2)" "unprognostic (6.53e-2)" "unprognostic (2.91e-2)" "unprognostic (5.53e-2)" "unprognostic (4.43e-2)" "potential prognostic favorable (5.70e-4)" "potential prognostic unfavorable (4.11e-6)" "unprognostic (2.09e-3)" "unprognostic (1.56e-2)" "unprognostic (1.87e-2)" "unprognostic (8.53e-2)" "unprognostic (1.53e-1)" "potential prognostic favorable (8.62e-4)" "unprognostic (2.35e-3)" "unprognostic (3.26e-3)" "validated prognostic unfavorable (4.47e-4)" "validated prognostic unfavorable (5.15e-4)" "unprognostic (2.51e-2)" "unprognostic (3.21e-2)" "unprognostic (8.29e-3)" "unprognostic (1.09e-1)" "unprognostic (2.87e-3)" "unprognostic (1.74e-2)" "unprognostic (1.14e-1)" "unprognostic (7.11e-2)" "potential prognostic favorable (6.87e-4)" "unprognostic (1.07e-1)" "unprognostic (9.17e-2)" "unprognostic (2.09e-1)" "unprognostic (2.65e-2)" "unprognostic (3.74e-3)" RPL3L ENSG00000140986 "Ribosomal protein L3 like" Q92901 16 1943974-1957606 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 165.9;skeletal muscle: 884.0;tongue: 394.7" "Cell type enriched" "Detected in some" 5 "Myonuclei: 352.0" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA049136 Enhanced Approved "Nuclear speckles" NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 9: Non-specific - Receptor signaling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 4 "Nuclear speckles" "HPA049136: " "unprognostic (2.27e-1)" "unprognostic (5.38e-3)" "unprognostic (1.93e-2)" "unprognostic (4.53e-2)" "unprognostic (3.64e-1)" "unprognostic (3.69e-2)" "unprognostic (3.06e-1)" "unprognostic (3.45e-1)" RPL4 L4 ENSG00000174444 "Ribosomal protein L4" P36578 15 66498015-66524532 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Decidual stromal cells: 3939.5;Esophageal basal cells: 3105.4;Esophageal suprabasal cells: 3042.4;Extravillous trophoblasts: 4187.2;Migrating cytotrophoblasts: 3127.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034600 Uncertain Supported "Nucleoli,Nuclear bodies,Endoplasmic reticulum,Cytosol" Yes No 380000 "Cluster 33: Non-specific - ATP binding" "Cluster 54: Non-specific - Ribosome" "Cluster 55: Non-specific - Transcription" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 505 "Endoplasmic reticulum, Cytosol" "Nucleoli, Nuclear bodies" "HPA034600: " "unprognostic (8.19e-3)" "unprognostic (2.22e-1)" "unprognostic (6.60e-3)" "unprognostic (2.02e-1)" "unprognostic (2.62e-1)" "unprognostic (1.33e-1)" "unprognostic (1.31e-2)" "unprognostic (1.40e-3)" "unprognostic (3.15e-2)" "unprognostic (1.62e-1)" "potential prognostic favorable (4.24e-7)" "unprognostic (4.96e-3)" "unprognostic (4.94e-2)" "unprognostic (3.36e-3)" "potential prognostic unfavorable (3.69e-7)" "potential prognostic unfavorable (6.65e-4)" "unprognostic (3.06e-3)" "unprognostic (1.33e-1)" "unprognostic (2.70e-1)" "unprognostic (2.20e-2)" "unprognostic (8.93e-2)" "unprognostic (1.41e-1)" "unprognostic (7.87e-2)" "unprognostic (1.50e-2)" "unprognostic (8.49e-2)" "unprognostic (2.08e-1)" "unprognostic (1.58e-1)" "unprognostic (2.06e-1)" "unprognostic (3.78e-1)" "unprognostic (2.01e-1)" "unprognostic (6.87e-2)" RPL41 L41 ENSG00000229117 "Ribosomal protein L41" P62945 12 56116590-56117967 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 3166.5;Breast secretory cells: 3279.3;Gastric chief cells: 10053.4;Mucous neck cells: 6117.4;Parietal cells: 7729.3;Suprabasal keratinocytes: 4120.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" HPA053169 Approved Supported "Endoplasmic reticulum" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 97: Non-specific - Cellular respiration" 2 "Endoplasmic reticulum" "HPA053169: " "unprognostic (7.10e-3)" "unprognostic (2.32e-2)" "unprognostic (1.18e-2)" "unprognostic (6.11e-3)" "unprognostic (3.08e-1)" "unprognostic (9.87e-2)" "unprognostic (7.22e-2)" "unprognostic (2.33e-1)" "unprognostic (3.90e-2)" "unprognostic (2.59e-1)" "validated prognostic favorable (5.05e-6)" "validated prognostic favorable (5.85e-4)" "unprognostic (1.90e-2)" "unprognostic (2.36e-3)" "unprognostic (1.15e-3)" "unprognostic (7.52e-2)" "unprognostic (4.95e-2)" "unprognostic (3.02e-2)" "unprognostic (4.00e-1)" "unprognostic (1.30e-1)" "unprognostic (1.16e-1)" "unprognostic (1.53e-1)" "unprognostic (4.29e-1)" "unprognostic (1.81e-1)" "unprognostic (4.88e-2)" "unprognostic (2.37e-1)" "unprognostic (1.53e-1)" "unprognostic (1.56e-1)" "unprognostic (5.62e-1)" "unprognostic (1.31e-1)" "unprognostic (9.72e-2)" RPL5 "L5, PPP1R135, uL18" ENSG00000122406 "Ribosomal protein L5" P46777 1 92832013-92841924 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding" "Cancer-related genes, Diamond-Blackfan anemia, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Decidual stromal cells: 5596.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Not detected" "Not detected" "HPA043717, HPA054444" Approved Supported "Nucleoli,Nucleoli rim,Endoplasmic reticulum,Cytosol" NA NA 260000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 480 "Endoplasmic reticulum, Cytosol" "Nucleoli, Nucleoli rim" "HPA043717: , HPA054444: " "unprognostic (8.83e-3)" "unprognostic (2.41e-3)" "unprognostic (7.57e-2)" "unprognostic (3.06e-2)" "unprognostic (1.31e-2)" "unprognostic (3.14e-1)" "unprognostic (1.20e-2)" "unprognostic (5.93e-2)" "unprognostic (3.22e-2)" "unprognostic (6.85e-2)" "unprognostic (2.01e-3)" "unprognostic (1.07e-3)" "unprognostic (3.50e-2)" "validated prognostic unfavorable (6.36e-6)" "validated prognostic unfavorable (2.79e-5)" "unprognostic (9.54e-2)" "unprognostic (3.20e-2)" "unprognostic (1.02e-1)" "unprognostic (1.58e-2)" "unprognostic (1.77e-2)" "unprognostic (1.36e-1)" "unprognostic (2.15e-1)" "unprognostic (3.26e-1)" "unprognostic (2.73e-1)" "unprognostic (8.47e-2)" "unprognostic (1.16e-1)" "unprognostic (2.02e-1)" "unprognostic (5.44e-2)" "unprognostic (2.21e-1)" "unprognostic (2.87e-1)" "unprognostic (3.19e-2)" RPL6 "L6, TAXREB107, TXREB1" ENSG00000089009 "Ribosomal protein L6" Q02878 12 112405189-112418838 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Decidual stromal cells: 6336.0;Esophageal suprabasal cells: 5447.9;Extravillous trophoblasts: 5036.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068418 Approved NA No 530000 "Cluster 30: Non-specific - DNA binding" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 203 "HPA068418: " "unprognostic (1.69e-2)" "unprognostic (2.00e-1)" "unprognostic (9.48e-2)" "unprognostic (1.12e-2)" "unprognostic (3.35e-2)" "unprognostic (2.24e-2)" "unprognostic (1.47e-1)" "potential prognostic favorable (5.92e-5)" "unprognostic (1.84e-1)" "unprognostic (1.62e-1)" "unprognostic (5.51e-2)" "unprognostic (1.71e-2)" "unprognostic (1.26e-2)" "validated prognostic unfavorable (4.29e-5)" "validated prognostic unfavorable (4.66e-7)" "unprognostic (3.33e-2)" "unprognostic (2.48e-2)" "unprognostic (2.75e-1)" "unprognostic (5.70e-2)" "unprognostic (1.63e-2)" "unprognostic (3.95e-2)" "unprognostic (2.27e-2)" "unprognostic (1.92e-2)" "unprognostic (5.02e-2)" "unprognostic (3.55e-3)" "unprognostic (3.71e-1)" "unprognostic (7.65e-2)" "unprognostic (4.87e-2)" "unprognostic (1.53e-1)" "unprognostic (2.14e-1)" "unprognostic (5.32e-3)" RPL7 "humL7-1, L7" ENSG00000147604 "Ribosomal protein L7" P18124 8 73290242-73295789 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Decidual stromal cells: 8936.9;Epididymal basal cells: 5576.8;Esophageal basal cells: 5173.2;Esophageal suprabasal cells: 5419.2;Extravillous trophoblasts: 5955.2;Ovarian stromal cells: 5905.7;Suprabasal keratinocytes: 5146.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058373 Approved Supported "Nucleoli,Endoplasmic reticulum,Cytosol" NA NA 530000 "Cluster 31: T-cells - T-cell receptor" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 167 "Endoplasmic reticulum, Cytosol" Nucleoli "HPA058373: " "unprognostic (1.02e-2)" "unprognostic (2.42e-1)" "unprognostic (2.17e-1)" "unprognostic (9.11e-3)" "unprognostic (4.91e-2)" "unprognostic (3.72e-3)" "unprognostic (3.02e-2)" "potential prognostic favorable (5.28e-5)" "unprognostic (1.04e-1)" "unprognostic (1.81e-1)" "unprognostic (3.96e-3)" "unprognostic (9.67e-2)" "potential prognostic unfavorable (8.54e-4)" "unprognostic (2.44e-2)" "unprognostic (6.27e-3)" "unprognostic (1.49e-1)" "unprognostic (6.61e-3)" "unprognostic (4.59e-2)" "unprognostic (2.41e-1)" "unprognostic (9.11e-3)" "unprognostic (7.76e-3)" "unprognostic (1.61e-1)" "unprognostic (3.23e-2)" "unprognostic (4.64e-1)" "unprognostic (2.46e-1)" "unprognostic (5.95e-2)" "unprognostic (1.53e-1)" "unprognostic (1.14e-1)" "unprognostic (2.82e-1)" "unprognostic (1.80e-1)" "unprognostic (1.45e-1)" RPL7A "L7A, SURF3, TRUP" ENSG00000148303 "Ribosomal protein L7a" P62424 9 133348218-133351426 "Disease related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal basal cells: 7552.9;Esophageal suprabasal cells: 8730.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046794 Approved Nucleoli,Vesicles NA NA 850000 "Cluster 18: Non-specific - Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 342 Nucleoli Vesicles "HPA046794: " "potential prognostic unfavorable (4.17e-4)" "unprognostic (5.66e-2)" "unprognostic (2.97e-2)" "unprognostic (7.54e-3)" "unprognostic (1.24e-1)" "potential prognostic unfavorable (4.16e-4)" "unprognostic (2.60e-2)" "potential prognostic favorable (9.34e-5)" "unprognostic (3.61e-2)" "unprognostic (1.56e-1)" "unprognostic (4.00e-3)" "unprognostic (8.21e-2)" "unprognostic (8.20e-2)" "validated prognostic unfavorable (8.69e-4)" "validated prognostic unfavorable (3.77e-5)" "unprognostic (7.77e-2)" "unprognostic (3.90e-2)" "unprognostic (4.04e-2)" "unprognostic (2.32e-1)" "potential prognostic unfavorable (1.98e-5)" "unprognostic (2.47e-1)" "unprognostic (2.50e-2)" "unprognostic (2.43e-1)" "unprognostic (1.14e-1)" "unprognostic (1.00e-1)" "unprognostic (3.23e-1)" "unprognostic (1.25e-1)" "unprognostic (7.68e-2)" "unprognostic (3.06e-1)" "unprognostic (5.28e-2)" "unprognostic (2.56e-2)" RPL7L1 dJ475N16.4 ENSG00000146223 "Ribosomal protein L7 like 1" Q6DKI1 6 42879616-42889925 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046049, HPA050478" Approved Nucleoli,Mitochondria NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 76: Non-specific - Metabolism" "Cluster 34: Non-specific - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 79 "Nucleoli, Mitochondria" "HPA046049: , HPA050478: " "unprognostic (3.84e-1)" "unprognostic (3.96e-3)" "unprognostic (2.78e-2)" "unprognostic (8.35e-3)" "unprognostic (7.31e-3)" "unprognostic (1.50e-1)" "unprognostic (2.07e-2)" "unprognostic (1.83e-3)" "unprognostic (9.81e-2)" "unprognostic (3.95e-3)" "potential prognostic favorable (7.79e-4)" "unprognostic (1.73e-3)" "unprognostic (1.60e-1)" "potential prognostic unfavorable (1.37e-4)" "unprognostic (1.34e-2)" "unprognostic (1.12e-1)" "unprognostic (4.48e-2)" "unprognostic (2.79e-1)" "unprognostic (1.03e-1)" "unprognostic (3.05e-1)" "unprognostic (3.04e-1)" "unprognostic (4.26e-1)" "unprognostic (5.41e-2)" "unprognostic (1.99e-1)" "unprognostic (1.35e-2)" "unprognostic (7.74e-2)" "potential prognostic unfavorable (8.78e-4)" "unprognostic (3.37e-1)" "unprognostic (1.25e-1)" "unprognostic (1.41e-2)" "unprognostic (1.32e-1)" RPL8 L8 ENSG00000161016 "Ribosomal protein L8" P62917 8 144789765-144792587 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Decidual stromal cells: 7961.6;Esophageal apical cells: 8675.6;Esophageal basal cells: 9307.1;Esophageal suprabasal cells: 10648.2;Extravillous trophoblasts: 8302.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA045095, HPA050165" Enhanced Supported "Nucleoli,Endoplasmic reticulum,Cytosol" NA NA 420000 "Cluster 18: Non-specific - Translation" "Cluster 24: Non-specific - Transcription" "Cluster 7: Non-specific - Ribosome" "Cluster 40: Non-specific - Unknown function" "Cluster 15: Non-specific - Protein processing" 229 "Nucleoli, Endoplasmic reticulum, Cytosol" "HPA045095: , HPA050165: " "unprognostic (6.86e-2)" "unprognostic (1.91e-1)" "unprognostic (2.84e-2)" "potential prognostic unfavorable (1.51e-4)" "unprognostic (2.13e-1)" "unprognostic (5.95e-3)" "unprognostic (1.19e-1)" "unprognostic (4.54e-2)" "unprognostic (1.27e-3)" "unprognostic (5.16e-2)" "unprognostic (7.80e-2)" "unprognostic (1.35e-1)" "unprognostic (3.97e-3)" "validated prognostic unfavorable (5.00e-4)" "validated prognostic unfavorable (2.31e-4)" "unprognostic (4.71e-3)" "unprognostic (2.45e-2)" "unprognostic (3.91e-2)" "unprognostic (3.23e-1)" "unprognostic (2.62e-1)" "unprognostic (2.28e-1)" "unprognostic (6.09e-2)" "unprognostic (2.86e-2)" "unprognostic (5.56e-2)" "unprognostic (7.83e-2)" "unprognostic (3.49e-1)" "unprognostic (3.34e-1)" "unprognostic (4.00e-2)" "unprognostic (2.22e-1)" "unprognostic (2.25e-2)" "unprognostic (1.53e-2)" RPL9 L9 ENSG00000163682 "Ribosomal protein L9" P32969 4 39452587-39458931 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal suprabasal cells: 6849.6;Extravillous trophoblasts: 6510.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003372 Approved Approved Supported "Nucleoli,Endoplasmic reticulum,Cytosol" NA NA 960000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 170 "Endoplasmic reticulum, Cytosol" Nucleoli "HPA003372: " "unprognostic (2.28e-1)" "unprognostic (5.30e-3)" "unprognostic (9.30e-2)" "potential prognostic favorable (2.64e-5)" "unprognostic (8.77e-2)" "unprognostic (1.74e-2)" "unprognostic (2.39e-1)" "unprognostic (4.95e-2)" "unprognostic (3.43e-3)" "unprognostic (3.77e-1)" "unprognostic (6.36e-2)" "unprognostic (1.66e-1)" "unprognostic (1.37e-2)" "unprognostic (1.02e-1)" "unprognostic (4.54e-2)" "unprognostic (3.48e-2)" "unprognostic (1.34e-1)" "unprognostic (1.13e-2)" "unprognostic (4.95e-2)" "unprognostic (8.04e-2)" "unprognostic (2.53e-1)" "unprognostic (2.71e-2)" "unprognostic (6.51e-2)" "unprognostic (3.64e-2)" "potential prognostic favorable (4.70e-5)" "unprognostic (1.03e-1)" "unprognostic (2.35e-1)" "unprognostic (1.03e-2)" "unprognostic (1.48e-1)" "unprognostic (1.04e-1)" "unprognostic (2.46e-1)" RPLP0 "L10E, LP0, P0, PRLP0, RPP0" ENSG00000089157 "Ribosomal protein lateral stalk subunit P0" P05388 12 120196699-120201235 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 6017.7;Esophageal apical cells: 5803.6;Esophageal suprabasal cells: 5437.8;Extravillous trophoblasts: 7011.7;Migrating cytotrophoblasts: 5561.6" "Cell type enhanced" "Detected in all" "leukocyte: 178.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA003512, HPA073501" Enhanced Supported "Endoplasmic reticulum,Cytosol" NA NA 1200000 "Cluster 30: Non-specific - DNA binding" "Cluster 54: Non-specific - Ribosome" "Cluster 44: Non-specific - Mixed function" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 375 "Endoplasmic reticulum, Cytosol" "HPA003512: , HPA073501: " "unprognostic (9.38e-3)" "unprognostic (7.91e-3)" "unprognostic (4.43e-1)" "unprognostic (1.32e-2)" "unprognostic (1.27e-1)" "unprognostic (1.03e-2)" "unprognostic (3.55e-2)" "unprognostic (3.83e-3)" "unprognostic (3.31e-2)" "unprognostic (6.55e-2)" "potential prognostic unfavorable (1.88e-4)" "unprognostic (1.99e-2)" "unprognostic (5.35e-3)" "validated prognostic unfavorable (6.53e-5)" "validated prognostic unfavorable (6.02e-6)" "unprognostic (1.97e-3)" "unprognostic (3.12e-2)" "unprognostic (1.25e-1)" "unprognostic (1.22e-1)" "unprognostic (5.73e-3)" "unprognostic (8.86e-2)" "unprognostic (1.19e-1)" "unprognostic (7.28e-2)" "unprognostic (1.38e-1)" "unprognostic (1.04e-2)" "unprognostic (1.68e-1)" "unprognostic (3.77e-1)" "unprognostic (9.73e-2)" "unprognostic (4.87e-1)" "unprognostic (2.39e-1)" "unprognostic (9.21e-2)" RPLP1 LP1 ENSG00000137818 "Ribosomal protein lateral stalk subunit P1" P05386 15 69452814-69456205 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 18714.5;Esophageal apical cells: 19806.6;Esophageal basal cells: 20047.4;Esophageal suprabasal cells: 23845.0;Suprabasal keratinocytes: 20461.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003368 Supported "Endoplasmic reticulum,Cytosol" NA NA 4300000 "Cluster 18: Non-specific - Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 80 "Endoplasmic reticulum, Cytosol" "HPA003368: " "unprognostic (1.29e-1)" "unprognostic (1.35e-2)" "unprognostic (2.59e-2)" "unprognostic (4.16e-2)" "unprognostic (9.98e-2)" "potential prognostic unfavorable (2.62e-4)" "unprognostic (2.17e-1)" "unprognostic (1.13e-2)" "unprognostic (4.08e-2)" "unprognostic (3.04e-2)" "potential prognostic unfavorable (6.90e-4)" "unprognostic (1.22e-2)" "unprognostic (3.34e-3)" "unprognostic (2.24e-2)" "potential prognostic unfavorable (1.63e-8)" "unprognostic (1.11e-1)" "unprognostic (1.05e-1)" "unprognostic (8.47e-3)" "unprognostic (3.75e-1)" "unprognostic (1.68e-1)" "unprognostic (9.12e-2)" "unprognostic (2.47e-1)" "unprognostic (1.57e-1)" "unprognostic (6.51e-2)" "unprognostic (3.98e-2)" "unprognostic (1.76e-1)" "unprognostic (2.73e-1)" "unprognostic (1.37e-1)" "unprognostic (3.10e-1)" "unprognostic (3.03e-1)" "unprognostic (1.76e-1)" RPLP2 "D11S2243E, LP2, MGC71408, P2, RPP2" ENSG00000177600 "Ribosomal protein lateral stalk subunit P2" P05387 11 809965-812880 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal suprabasal cells: 10090.5;Extravillous trophoblasts: 10105.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Liver - Vascular endothelial cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053635, HPA075365" Approved Approved "Nuclear speckles,Mitotic spindle,Cytosol" Yes NA 3200000 "Cluster 24: Non-specific - Transcription" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 152 "Nuclear speckles, Cytosol" "Mitotic spindle" "HPA053635: , HPA075365: " "unprognostic (1.68e-1)" "unprognostic (1.04e-2)" "unprognostic (6.25e-2)" "unprognostic (2.14e-1)" "unprognostic (3.73e-2)" "unprognostic (6.60e-3)" "unprognostic (1.97e-1)" "unprognostic (9.38e-2)" "unprognostic (1.32e-1)" "unprognostic (6.54e-2)" "potential prognostic unfavorable (6.16e-5)" "unprognostic (2.81e-2)" "potential prognostic unfavorable (2.05e-5)" "validated prognostic unfavorable (4.00e-5)" "validated prognostic unfavorable (7.34e-5)" "unprognostic (1.20e-1)" "unprognostic (2.48e-3)" "unprognostic (1.71e-1)" "unprognostic (1.07e-1)" "unprognostic (1.39e-1)" "unprognostic (8.16e-2)" "unprognostic (2.32e-1)" "unprognostic (5.52e-1)" "unprognostic (1.82e-1)" "unprognostic (1.04e-2)" "unprognostic (2.99e-1)" "unprognostic (1.39e-1)" "unprognostic (1.22e-1)" "unprognostic (8.33e-2)" "unprognostic (2.56e-1)" "unprognostic (1.76e-1)" RPN1 OST1 ENSG00000163902 "Ribophorin I" P04843 3 128619969-128681075 "Cancer-related genes, Essential proteins, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Macrophages, Heart muscle - Macrophages, Liver - Hepatocytes, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009748, HPA026828, HPA051520" Enhanced Enhanced "Endoplasmic reticulum,Cytosol" NA NA 460000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 22: Epididymis - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 8: Non-specific - Secretory pathway" 246 "Endoplasmic reticulum" Cytosol "CAB009748: , HPA026828: , HPA051520: " "unprognostic (1.09e-1)" "unprognostic (6.71e-2)" "unprognostic (2.56e-2)" "unprognostic (2.06e-1)" "unprognostic (1.88e-1)" "unprognostic (1.34e-1)" "unprognostic (6.99e-2)" "unprognostic (2.10e-1)" "unprognostic (3.14e-2)" "unprognostic (2.71e-3)" "unprognostic (6.29e-3)" "unprognostic (3.62e-2)" "unprognostic (7.09e-2)" "validated prognostic unfavorable (1.61e-5)" "validated prognostic unfavorable (1.89e-6)" "unprognostic (9.03e-2)" "unprognostic (7.44e-3)" "unprognostic (2.93e-1)" "unprognostic (2.56e-2)" "unprognostic (2.45e-1)" "unprognostic (3.08e-1)" "unprognostic (1.60e-3)" "unprognostic (5.72e-1)" "unprognostic (1.26e-1)" "unprognostic (2.84e-1)" "unprognostic (2.60e-1)" "unprognostic (1.82e-1)" "unprognostic (1.35e-1)" "unprognostic (4.75e-2)" "unprognostic (1.83e-1)" "unprognostic (5.23e-2)" RPN2 "RIBIIR, RPN-II, RPNII, SWP1" ENSG00000118705 "Ribophorin II" P04844 20 37178410-37241619 "Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 858.8;Oocytes: 1128.2;Plasma cells: 576.8;Syncytiotrophoblasts: 802.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Macrophages, Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008297, CAB019277, HPA025922" Enhanced Supported "Endoplasmic reticulum" NA NA 1300000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 22: Epididymis - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 8: Non-specific - Secretory pathway" 197 "Endoplasmic reticulum" "CAB019277: , HPA008297: , HPA025922: " "unprognostic (3.35e-1)" "unprognostic (1.22e-3)" "unprognostic (7.30e-2)" "unprognostic (4.50e-2)" "unprognostic (5.85e-2)" "unprognostic (2.05e-1)" "unprognostic (1.77e-1)" "unprognostic (9.27e-2)" "unprognostic (1.78e-2)" "potential prognostic unfavorable (7.02e-6)" "unprognostic (2.60e-3)" "potential prognostic unfavorable (2.48e-4)" "unprognostic (1.75e-1)" "validated prognostic unfavorable (1.94e-4)" "validated prognostic unfavorable (6.08e-4)" "unprognostic (7.76e-2)" "unprognostic (3.11e-2)" "unprognostic (5.93e-2)" "unprognostic (6.79e-2)" "unprognostic (1.91e-1)" "unprognostic (1.48e-1)" "unprognostic (9.73e-2)" "unprognostic (2.36e-1)" "unprognostic (3.29e-1)" "unprognostic (7.46e-2)" "unprognostic (4.11e-2)" "unprognostic (3.42e-1)" "unprognostic (1.45e-1)" "unprognostic (3.68e-2)" "unprognostic (1.04e-1)" "unprognostic (8.22e-2)" RPP14 P14 ENSG00000163684 "Ribonuclease P/MRP subunit p14" O95059 3 58306245-58324695 "Essential proteins, Metabolic proteins, Predicted intracellular proteins" "tRNA processing" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 38.1;tongue: 36.4" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 10.8;Myonuclei: 11.1;Thymic myoid cells: 10.9" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" HPA036194 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 37: Neurons - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 105: Non-specific - Mixed function" 32 "Nucleoplasm, Cytosol" "HPA036194: " "unprognostic (1.84e-2)" "unprognostic (1.72e-1)" "unprognostic (7.76e-2)" "unprognostic (4.18e-2)" "unprognostic (3.30e-3)" "unprognostic (7.74e-2)" "unprognostic (3.03e-1)" "unprognostic (1.17e-1)" "unprognostic (8.88e-2)" "unprognostic (5.51e-3)" "potential prognostic favorable (8.50e-8)" "unprognostic (1.91e-3)" "unprognostic (2.48e-1)" "unprognostic (3.55e-2)" "unprognostic (3.46e-2)" "unprognostic (2.88e-2)" "unprognostic (1.29e-2)" "unprognostic (1.94e-1)" "unprognostic (1.71e-1)" "unprognostic (1.75e-1)" "unprognostic (1.64e-2)" "unprognostic (5.84e-2)" "unprognostic (4.90e-2)" "unprognostic (4.05e-2)" "unprognostic (5.91e-2)" "unprognostic (2.42e-2)" "unprognostic (1.54e-1)" "unprognostic (4.29e-2)" "unprognostic (3.01e-1)" "potential prognostic unfavorable (3.69e-4)" "unprognostic (7.72e-2)" RPP21 "C6orf135, Em:AB014085.3, FLJ22638" ENSG00000241370 "Ribonuclease P/MRP subunit p21" Q9H633 6 30345131-30346884 "Essential proteins, Predicted intracellular proteins" "tRNA processing" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Gastric chief cells: 39.3;Oligodendrocytes: 22.9;Oocytes: 36.8;Other brain neurons: 24.2;Paneth cells: 27.1;Parietal cells: 30.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in all" 5 "Adrenocortical cancer: 108.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 64: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 98: Neurons - Neurotransmission & signaling" 19 "unprognostic (1.04e-1)" "unprognostic (3.87e-1)" "unprognostic (3.53e-1)" "unprognostic (1.01e-1)" "unprognostic (1.34e-1)" "unprognostic (1.37e-1)" "unprognostic (9.33e-2)" "unprognostic (5.57e-3)" "unprognostic (1.46e-3)" "unprognostic (1.14e-1)" "unprognostic (6.80e-2)" "unprognostic (2.00e-1)" "unprognostic (9.35e-2)" "unprognostic (1.45e-1)" "potential prognostic unfavorable (7.29e-4)" "unprognostic (1.01e-1)" "unprognostic (8.27e-2)" "unprognostic (1.86e-1)" "unprognostic (4.60e-2)" "unprognostic (3.11e-1)" "unprognostic (7.79e-2)" "unprognostic (2.19e-1)" "unprognostic (1.50e-2)" "unprognostic (1.48e-1)" "unprognostic (2.59e-2)" "unprognostic (1.53e-1)" "unprognostic (1.46e-3)" "unprognostic (2.61e-1)" "unprognostic (8.63e-2)" "unprognostic (1.88e-1)" "unprognostic (1.83e-2)" RPP25 FLJ20374 ENSG00000178718 "Ribonuclease P and MRP subunit p25" Q9BUL9 15 74954418-74956772 "Predicted intracellular proteins" "rRNA processing, tRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 38.4;Hofbauer cells: 154.4;Ovarian stromal cells: 43.8;Retinal bipolar cells: 54.9" "Cell type enhanced" "Detected in many" "midbrain-derived inhibitory: 32.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 25.9" "Group enriched" "Detected in many" 5 "dendritic cells: 25.9;monocytes: 10.1" "Low cancer specificity" "Detected in all" "Skeletal muscle - Macrophages" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "olfactory bulb: 30.7" HPA046900 Approved Supported "Nucleoplasm,Centriolar satellite" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 51 Nucleoplasm "Centriolar satellite" "HPA046900: " "unprognostic (1.30e-3)" "unprognostic (1.70e-1)" "unprognostic (1.35e-1)" "unprognostic (1.76e-1)" "unprognostic (1.08e-1)" "unprognostic (9.52e-3)" "potential prognostic unfavorable (1.56e-5)" "unprognostic (6.31e-2)" "unprognostic (5.36e-2)" "unprognostic (2.95e-2)" "unprognostic (2.18e-2)" "unprognostic (2.28e-2)" "potential prognostic favorable (7.59e-5)" "unprognostic (2.21e-3)" "unprognostic (9.10e-2)" "potential prognostic unfavorable (3.37e-6)" "unprognostic (9.01e-2)" "unprognostic (3.16e-1)" "unprognostic (3.77e-1)" "unprognostic (3.82e-2)" "unprognostic (1.65e-1)" "unprognostic (8.78e-3)" "unprognostic (3.23e-2)" "unprognostic (2.42e-1)" "unprognostic (2.77e-1)" "unprognostic (1.52e-1)" "unprognostic (2.58e-1)" "unprognostic (2.80e-2)" "unprognostic (1.11e-1)" "unprognostic (7.56e-2)" "unprognostic (3.90e-1)" RPP25L "bA296L22.5, C9orf23, MGC29635" ENSG00000164967 "Ribonuclease P/MRP subunit p25 like" Q8N5L8 9 34610486-34612104 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 115.5" "Cell type enhanced" "Detected in many" "Enterocytes: 120.6;Hepatocytes: 87.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052187, HPA059698" Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 33 Nucleoplasm "Nucleoli, Cytosol" "HPA052187: , HPA059698: " "unprognostic (1.31e-1)" "unprognostic (3.58e-1)" "unprognostic (3.93e-1)" "unprognostic (4.99e-2)" "unprognostic (4.94e-2)" "unprognostic (1.24e-1)" "unprognostic (2.58e-2)" "unprognostic (1.12e-1)" "unprognostic (5.11e-2)" "potential prognostic favorable (9.71e-8)" "unprognostic (2.33e-3)" "unprognostic (3.97e-3)" "unprognostic (2.46e-2)" "unprognostic (4.01e-2)" "potential prognostic unfavorable (9.67e-4)" "unprognostic (5.57e-2)" "unprognostic (2.95e-2)" "unprognostic (2.17e-1)" "unprognostic (2.93e-3)" "unprognostic (3.28e-2)" "unprognostic (4.12e-3)" "unprognostic (1.47e-1)" "unprognostic (2.82e-1)" "unprognostic (1.20e-1)" "unprognostic (3.55e-2)" "unprognostic (2.44e-2)" "unprognostic (4.71e-1)" "unprognostic (2.12e-1)" "unprognostic (1.95e-3)" RPP30 TSG15 ENSG00000148688 "Ribonuclease P/MRP subunit p30" P78346 10 90871952-90908553 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "rRNA processing, tRNA processing" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 160.0;Oocytes: 299.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037578 Approved Approved "Nucleoplasm,Nucleoli,Microtubule ends,Cytosol" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 39: Testis - Nuclear processes" "Cluster 34: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 7: Non-specific - Transcription" 57 "Nucleoplasm, Nucleoli" "Microtubule ends, Cytosol" "HPA037578: " "unprognostic (5.02e-2)" "unprognostic (1.94e-2)" "unprognostic (2.56e-1)" "unprognostic (2.72e-1)" "unprognostic (2.10e-2)" "unprognostic (1.37e-1)" "unprognostic (1.07e-1)" "potential prognostic favorable (1.51e-4)" "unprognostic (4.15e-3)" "unprognostic (7.16e-3)" "unprognostic (3.94e-3)" "unprognostic (1.02e-1)" "potential prognostic unfavorable (9.32e-4)" "potential prognostic unfavorable (1.15e-4)" "unprognostic (1.51e-2)" "validated prognostic unfavorable (7.04e-4)" "validated prognostic unfavorable (1.79e-4)" "unprognostic (2.58e-3)" "unprognostic (2.83e-1)" "unprognostic (4.89e-1)" "unprognostic (1.35e-2)" "unprognostic (4.19e-3)" "potential prognostic unfavorable (1.02e-4)" "unprognostic (6.30e-2)" "unprognostic (1.03e-1)" "unprognostic (1.23e-1)" "unprognostic (2.15e-1)" "unprognostic (1.08e-2)" "unprognostic (1.80e-1)" "unprognostic (1.35e-1)" "unprognostic (5.42e-2)" RPP38 ENSG00000152464 "Ribonuclease P/MRP subunit p38" P78345 10 15097180-15139818 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "rRNA processing, tRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 188.2;Early spermatids: 551.0;Late primary spermatocytes: 416.3;Late spermatids: 306.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045128, HPA050398" Approved Supported Nucleoli NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 39: Testis - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 28 Nucleoli "HPA045128: , HPA050398: " "unprognostic (1.79e-1)" "unprognostic (6.86e-2)" "unprognostic (3.75e-1)" "unprognostic (5.17e-3)" "unprognostic (2.08e-1)" "unprognostic (8.88e-2)" "unprognostic (1.46e-1)" "potential prognostic favorable (1.50e-6)" "unprognostic (5.20e-2)" "unprognostic (1.40e-1)" "unprognostic (7.10e-2)" "unprognostic (9.32e-2)" "unprognostic (1.05e-1)" "potential prognostic unfavorable (3.01e-4)" "unprognostic (1.32e-2)" "unprognostic (3.18e-2)" "unprognostic (2.79e-2)" "unprognostic (2.40e-2)" "unprognostic (1.81e-1)" "unprognostic (4.32e-2)" "unprognostic (3.20e-2)" "unprognostic (1.34e-1)" "unprognostic (2.34e-1)" "unprognostic (4.41e-2)" "unprognostic (4.36e-2)" "unprognostic (7.13e-2)" "unprognostic (1.51e-1)" "unprognostic (1.49e-1)" "unprognostic (2.77e-1)" "unprognostic (5.62e-2)" "unprognostic (3.20e-1)" RPP40 "bA428J1.3, RNASEP1" ENSG00000124787 "Ribonuclease P/MRP subunit p40" O75818 6 4994717-5004063 "Essential proteins, Predicted intracellular proteins" "rRNA processing, tRNA processing" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 29.7;Differentiating spermatogonia: 31.5;Esophageal basal cells: 42.2;Esophageal suprabasal cells: 35.3;Gastric progenitor cells: 33.3;Oocytes: 119.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 72.7" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035685, HPA035686" Uncertain Approved Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 14 Nucleoplasm "HPA035685: , HPA035686: " "unprognostic (8.78e-2)" "unprognostic (2.65e-3)" "unprognostic (4.58e-1)" "unprognostic (2.56e-1)" "unprognostic (5.79e-2)" "unprognostic (2.52e-1)" "unprognostic (1.79e-1)" "unprognostic (1.21e-2)" "unprognostic (1.24e-1)" "unprognostic (1.85e-1)" "potential prognostic unfavorable (2.92e-4)" "unprognostic (4.09e-2)" "unprognostic (3.78e-3)" "potential prognostic unfavorable (1.40e-4)" "unprognostic (8.86e-3)" "unprognostic (3.40e-3)" "unprognostic (8.55e-3)" "unprognostic (1.34e-2)" "unprognostic (8.55e-2)" "unprognostic (2.43e-2)" "unprognostic (4.54e-3)" "unprognostic (4.18e-2)" "unprognostic (2.17e-1)" "unprognostic (9.04e-2)" "unprognostic (1.18e-2)" "unprognostic (6.84e-2)" "potential prognostic unfavorable (1.34e-4)" "unprognostic (1.24e-1)" "unprognostic (3.61e-1)" "unprognostic (6.48e-3)" "unprognostic (4.96e-3)" RPRD1A "FLJ10656, HsT3101, P15RS" ENSG00000141425 "Regulation of nuclear pre-mRNA domain containing 1A" Q96P16 18 35984387-36067576 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epididymal principal cells: 434.4;Late spermatids: 555.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040602 Supported Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 22: Epididymis - Mixed function" "Cluster 34: Non-specific - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 24: Neutrophils - Innate immunity signal integration" 20 "Nucleoplasm, Golgi apparatus" "HPA040602: " "unprognostic (5.95e-2)" "unprognostic (6.16e-2)" "unprognostic (1.66e-1)" "unprognostic (3.30e-2)" "unprognostic (8.52e-2)" "unprognostic (2.64e-2)" "unprognostic (1.20e-3)" "potential prognostic favorable (5.04e-5)" "unprognostic (1.48e-1)" "unprognostic (3.67e-3)" "potential prognostic favorable (1.84e-5)" "unprognostic (8.54e-3)" "potential prognostic favorable (3.57e-4)" "validated prognostic unfavorable (1.33e-4)" "validated prognostic unfavorable (2.27e-4)" "unprognostic (1.81e-1)" "unprognostic (1.30e-1)" "unprognostic (1.74e-2)" "unprognostic (2.45e-2)" "unprognostic (5.58e-2)" "unprognostic (8.82e-2)" "unprognostic (2.19e-1)" "unprognostic (2.96e-1)" "unprognostic (1.61e-1)" "unprognostic (1.05e-2)" "unprognostic (2.28e-2)" "unprognostic (3.97e-2)" "unprognostic (1.85e-1)" "unprognostic (8.04e-3)" "unprognostic (1.15e-1)" "unprognostic (2.83e-2)" RPRD1B "C20orf77, CREPT, dJ1057B20.2, DKFZp434P0735, FLJ44520, K-H, Kub5-Hera, NET60" ENSG00000101413 "Regulation of nuclear pre-mRNA domain containing 1B" Q9NQG5 20 38033725-38127780 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 74.0" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066290, HPA070590, HPA072645" Enhanced Supported Nucleoplasm NA NA 13000 "Cluster 7: Non-specific - Innate immune response" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 55: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 7: Non-specific - Transcription" 70 Nucleoplasm "HPA066290: , HPA070590: , HPA072645: " "unprognostic (3.31e-1)" "unprognostic (1.80e-2)" "unprognostic (8.41e-2)" "unprognostic (4.23e-2)" "unprognostic (7.83e-2)" "unprognostic (2.56e-1)" "unprognostic (3.92e-1)" "unprognostic (1.26e-1)" "unprognostic (4.68e-2)" "unprognostic (1.16e-3)" "unprognostic (1.13e-3)" "unprognostic (4.72e-2)" "unprognostic (1.38e-1)" "unprognostic (1.09e-2)" "unprognostic (2.48e-2)" "unprognostic (9.55e-2)" "unprognostic (6.51e-3)" "unprognostic (8.58e-3)" "unprognostic (2.77e-1)" "unprognostic (2.88e-2)" "unprognostic (1.45e-1)" "unprognostic (8.97e-2)" "potential prognostic unfavorable (7.77e-4)" "unprognostic (6.96e-2)" "unprognostic (3.96e-3)" "unprognostic (1.73e-2)" "unprognostic (1.52e-1)" "unprognostic (7.22e-2)" "unprognostic (2.08e-1)" "unprognostic (4.06e-3)" "unprognostic (2.35e-2)" RPRD2 "FLJ32145, HSPC099, KIAA0460" ENSG00000163125 "Regulation of nuclear pre-mRNA domain containing 2" Q5VT52 1 150363091-150476566 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061693 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" 26 "Nucleoplasm, Vesicles" "HPA061693: " "unprognostic (3.76e-3)" "unprognostic (1.39e-1)" "unprognostic (2.92e-1)" "unprognostic (2.11e-2)" "unprognostic (1.97e-1)" "unprognostic (5.15e-3)" "unprognostic (1.54e-2)" "unprognostic (1.08e-1)" "unprognostic (1.02e-1)" "unprognostic (1.18e-2)" "validated prognostic favorable (4.33e-9)" "validated prognostic favorable (4.81e-4)" "unprognostic (1.61e-1)" "unprognostic (7.32e-3)" "unprognostic (1.07e-1)" "unprognostic (1.04e-1)" "unprognostic (9.30e-2)" "unprognostic (1.61e-1)" "unprognostic (1.93e-1)" "unprognostic (5.87e-2)" "unprognostic (8.01e-2)" "unprognostic (3.22e-2)" "unprognostic (1.61e-1)" "unprognostic (1.65e-1)" "unprognostic (4.88e-2)" "unprognostic (1.16e-1)" "unprognostic (2.36e-1)" "unprognostic (7.99e-2)" "unprognostic (3.06e-1)" "unprognostic (1.13e-1)" "unprognostic (1.08e-1)" RPRM "FLJ90327, REPRIMO" ENSG00000177519 "Reprimo, TP53 dependent G2 arrest mediator homolog" Q9NS64 2 153477338-153478762 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Papillary tip epithelial cells: 2.2;Respiratory deuterosomal cells: 1.0" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "Glioblastoma Multiforme (TCGA): 12.3;Testicular Germ Cell Tumor (TCGA): 45.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 8.7" "Adipose visceral - Mesothelial cells, Pituitary gland - Corticotropes, Stomach - Parietal cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 68 "potential prognostic favorable (6.78e-4)" "unprognostic (2.37e-1)" "unprognostic (8.16e-2)" "unprognostic (3.94e-2)" "potential prognostic favorable (8.75e-5)" "unprognostic (1.98e-1)" "unprognostic (6.44e-2)" "unprognostic (2.31e-1)" "unprognostic (2.57e-1)" "unprognostic (2.59e-3)" "unprognostic (1.76e-1)" "unprognostic (1.77e-1)" "unprognostic (3.98e-1)" "unprognostic (5.98e-2)" "unprognostic (6.74e-3)" "unprognostic (2.99e-1)" RPRML MGC43894 ENSG00000179673 "Reprimo like" Q8N4K4 17 46978156-46979253 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 25 "brain: 47.2" "Group enriched" "Detected in some" 6 "Brain excitatory neurons: 16.0;Brain inhibitory neurons: 15.3;Epididymal efferent duct ciliated cells: 36.1;Epididymal principal cells: 60.1;Neuroendocrine cells: 48.1" "Cell type enhanced" "Detected in many" "deep-layer corticothalamic and 6b: 41.7;medium spiny neuron: 45.3" "Group enriched" "Detected in some" 4 "Glioblastoma Multiforme (TCGA): 1.9;Testicular Germ Cell Tumor (TCGA): 4.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 8.0" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "basal ganglia: 118.6" HPA062668 Uncertain NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" "HPA062668: " "unprognostic (7.00e-2)" "unprognostic (2.88e-1)" "unprognostic (2.78e-1)" RPS10 "MGC88819, S10" ENSG00000124614 "Ribosomal protein S10" P46783 6 34417454-34426069 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Diamond-Blackfan anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enteric stem cells: 2419.2;Enteric transient amplifying cells: 2348.2;Epididymal basal cells: 2711.3;Epididymal efferent duct absorptive cells: 2625.2;Gastric progenitor cells: 3355.4;Paneth cells: 2223.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047268, HPA048084" Approved Approved Cytosol NA NA 45000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 256 Cytosol "HPA047268: , HPA048084: " "unprognostic (7.90e-3)" "unprognostic (2.64e-1)" "unprognostic (2.54e-1)" "unprognostic (5.55e-3)" "unprognostic (1.44e-1)" "unprognostic (1.69e-1)" "unprognostic (3.57e-2)" "unprognostic (1.31e-2)" "unprognostic (1.26e-2)" "unprognostic (2.05e-1)" "unprognostic (1.33e-1)" "unprognostic (1.19e-1)" "unprognostic (3.11e-2)" "unprognostic (2.66e-3)" "potential prognostic unfavorable (1.92e-5)" "unprognostic (7.57e-2)" "unprognostic (4.78e-2)" "unprognostic (2.29e-3)" "unprognostic (2.74e-1)" "unprognostic (7.76e-2)" "unprognostic (1.14e-1)" "unprognostic (3.15e-1)" "unprognostic (2.80e-1)" "unprognostic (2.30e-1)" "potential prognostic favorable (3.91e-4)" "unprognostic (6.81e-2)" "unprognostic (8.01e-2)" "unprognostic (1.76e-2)" "unprognostic (2.52e-1)" "unprognostic (2.35e-1)" "unprognostic (1.75e-1)" RPS10-NUDT3 ENSG00000270800 "RPS10-NUDT3 readthrough" 6 34284887-34426071 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 25.3;Cardiomyocytes: 30.6;Retinal ganglion cells: 23.2;Suprabasal keratinocytes: 33.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 27.3" "Lineage enriched" "Detected in all" 4 "granulocytes: 27.3" "Low cancer specificity" "Detected in all" "HPA047027, HPA047268, HPA048084, HPA055953" Uncertain Approved Cytosol NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 61: BICR 18 - Protein kinases" "Cluster 26: Keratinocytes - Keratinization" 1 Cytosol "HPA047027: , HPA047268: , HPA048084: , HPA055953: " "unprognostic (5.59e-2)" "unprognostic (2.53e-1)" "unprognostic (3.23e-1)" "unprognostic (2.90e-2)" "unprognostic (2.55e-2)" "unprognostic (2.52e-1)" "potential prognostic favorable (2.05e-4)" "potential prognostic unfavorable (4.26e-4)" "potential prognostic unfavorable (3.21e-4)" "unprognostic (1.24e-3)" "unprognostic (1.12e-1)" "unprognostic (4.66e-3)" "unprognostic (7.01e-3)" "potential prognostic unfavorable (8.86e-4)" "unprognostic (3.13e-3)" "unprognostic (5.06e-2)" "unprognostic (1.14e-1)" "unprognostic (1.71e-1)" "unprognostic (1.56e-3)" "unprognostic (5.80e-3)" "unprognostic (2.34e-3)" "unprognostic (9.52e-3)" "unprognostic (1.50e-2)" "unprognostic (2.34e-2)" "unprognostic (1.61e-1)" "unprognostic (7.38e-2)" "unprognostic (1.15e-1)" RPS11 S11 ENSG00000142534 "Ribosomal protein S11" P62280 19 49496365-49499708 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal suprabasal cells: 5054.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032020, HPA049719" Uncertain Approved "Nucleoli,Endoplasmic reticulum,Cytosol" NA NA 22000 "Cluster 18: Non-specific - Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 271 Cytosol "Nucleoli, Endoplasmic reticulum" "HPA032020: , HPA049719: " "unprognostic (2.97e-2)" "unprognostic (1.57e-2)" "unprognostic (5.49e-2)" "unprognostic (3.16e-2)" "unprognostic (1.79e-1)" "unprognostic (5.14e-2)" "unprognostic (1.28e-2)" "unprognostic (2.02e-1)" "unprognostic (1.71e-1)" "unprognostic (8.94e-2)" "unprognostic (4.90e-2)" "unprognostic (9.31e-2)" "potential prognostic unfavorable (7.30e-4)" "potential prognostic unfavorable (8.11e-4)" "unprognostic (3.24e-3)" "unprognostic (6.03e-3)" "unprognostic (4.00e-2)" "unprognostic (1.85e-2)" "unprognostic (2.73e-1)" "unprognostic (2.54e-2)" "unprognostic (4.31e-2)" "unprognostic (2.25e-1)" "unprognostic (2.43e-2)" "unprognostic (1.11e-1)" "unprognostic (2.80e-1)" "unprognostic (1.45e-1)" "unprognostic (2.13e-1)" "unprognostic (1.09e-1)" "unprognostic (1.29e-1)" "unprognostic (1.20e-1)" "unprognostic (4.73e-2)" RPS12 S12 ENSG00000112306 "Ribosomal protein S12" P25398 6 132814569-132817564 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal suprabasal cells: 15972.8;Gastric progenitor cells: 19991.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006124, HPA006365" Approved Supported "Golgi apparatus,Vesicles,Cytosol" NA NA 830000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 118 Cytosol "Golgi apparatus, Vesicles" "HPA006124: , HPA006365: " "unprognostic (9.20e-2)" "unprognostic (1.55e-1)" "unprognostic (2.58e-1)" "unprognostic (1.28e-2)" "unprognostic (1.56e-1)" "unprognostic (3.42e-1)" "unprognostic (4.36e-3)" "unprognostic (1.10e-2)" "unprognostic (4.34e-3)" "unprognostic (2.32e-2)" "unprognostic (1.65e-3)" "unprognostic (1.19e-2)" "unprognostic (3.11e-3)" "validated prognostic unfavorable (1.71e-4)" "validated prognostic unfavorable (2.95e-4)" "unprognostic (1.07e-1)" "unprognostic (2.67e-1)" "unprognostic (8.69e-2)" "unprognostic (1.38e-2)" "unprognostic (4.56e-3)" "unprognostic (1.54e-2)" "unprognostic (2.86e-1)" "unprognostic (6.59e-2)" "unprognostic (1.97e-2)" "unprognostic (1.45e-2)" "unprognostic (1.62e-1)" "unprognostic (6.11e-2)" "unprognostic (5.20e-1)" "unprognostic (7.87e-2)" "unprognostic (1.57e-1)" "unprognostic (2.50e-2)" RPS13 S13 ENSG00000110700 "Ribosomal protein S13" P62277 11 17074388-17077715 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 6621.6;Esophageal basal cells: 6266.6;Esophageal suprabasal cells: 7770.0;Extravillous trophoblasts: 6522.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005985 Uncertain Approved "Endoplasmic reticulum" NA NA 120000 "Cluster 18: Non-specific - Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 198 "Endoplasmic reticulum" "HPA005985: " "unprognostic (1.99e-2)" "unprognostic (2.11e-2)" "unprognostic (1.08e-2)" "unprognostic (2.51e-2)" "unprognostic (1.52e-1)" "unprognostic (5.56e-2)" "unprognostic (3.06e-1)" "unprognostic (3.45e-1)" "unprognostic (1.64e-2)" "unprognostic (6.91e-3)" "unprognostic (1.66e-3)" "unprognostic (7.20e-2)" "unprognostic (1.77e-2)" "validated prognostic unfavorable (1.32e-5)" "validated prognostic unfavorable (7.44e-4)" "unprognostic (2.98e-1)" "unprognostic (9.03e-2)" "unprognostic (8.01e-2)" "unprognostic (1.16e-1)" "unprognostic (2.51e-2)" "unprognostic (9.27e-3)" "unprognostic (4.73e-2)" "unprognostic (1.74e-1)" "unprognostic (2.88e-1)" "potential prognostic favorable (9.09e-4)" "unprognostic (3.37e-2)" "unprognostic (1.51e-1)" "unprognostic (2.20e-2)" "unprognostic (1.39e-1)" "unprognostic (2.07e-1)" "unprognostic (7.58e-2)" RPS14 "EMTB, S14" ENSG00000164587 "Ribosomal protein S14" P62263 5 150442635-150449739 "Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal basal cells: 11350.9;Esophageal suprabasal cells: 13114.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018504 Approved Supported "Endoplasmic reticulum,Cytosol" NA NA 1200000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 181 "Endoplasmic reticulum, Cytosol" "HPA018504: " "unprognostic (2.45e-1)" "unprognostic (3.85e-3)" "unprognostic (7.16e-2)" "unprognostic (1.05e-1)" "unprognostic (1.89e-2)" "unprognostic (1.43e-1)" "unprognostic (7.73e-2)" "unprognostic (9.64e-2)" "unprognostic (3.67e-2)" "unprognostic (3.50e-2)" "unprognostic (2.44e-2)" "unprognostic (2.12e-1)" "unprognostic (3.19e-2)" "validated prognostic unfavorable (1.53e-6)" "validated prognostic unfavorable (4.35e-4)" "unprognostic (3.53e-1)" "unprognostic (7.14e-2)" "unprognostic (9.47e-2)" "unprognostic (3.00e-2)" "unprognostic (1.71e-1)" "unprognostic (1.80e-1)" "unprognostic (1.02e-1)" "unprognostic (8.19e-2)" "unprognostic (1.84e-1)" "unprognostic (1.83e-2)" "unprognostic (1.56e-1)" "unprognostic (6.51e-2)" "unprognostic (8.99e-2)" "unprognostic (8.69e-2)" "unprognostic (2.89e-1)" "unprognostic (1.02e-2)" RPS15 "MGC111130, RIG, S15" ENSG00000115268 "Ribosomal protein S15" P62841 19 1438358-1440495 "Cancer-related genes, Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal suprabasal cells: 8565.1;Suprabasal keratinocytes: 8284.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054510, HPA057793" Enhanced Approved "Endoplasmic reticulum,Cytosol" NA NA 480000 "Cluster 18: Non-specific - Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 129 "Endoplasmic reticulum, Cytosol" "HPA054510: , HPA057793: " "unprognostic (1.01e-1)" "unprognostic (6.88e-3)" "unprognostic (1.13e-1)" "unprognostic (3.17e-2)" "unprognostic (1.08e-2)" "unprognostic (1.30e-2)" "unprognostic (2.33e-2)" "unprognostic (1.06e-2)" "unprognostic (3.17e-1)" "unprognostic (1.86e-1)" "unprognostic (3.71e-2)" "unprognostic (5.19e-2)" "unprognostic (8.42e-3)" "validated prognostic unfavorable (8.21e-4)" "validated prognostic unfavorable (9.67e-5)" "unprognostic (6.63e-3)" "unprognostic (9.48e-3)" "unprognostic (3.53e-2)" "unprognostic (2.42e-1)" "unprognostic (5.21e-2)" "unprognostic (7.72e-2)" "unprognostic (1.93e-2)" "unprognostic (2.40e-1)" "unprognostic (3.00e-2)" "unprognostic (1.98e-1)" "unprognostic (5.85e-1)" "unprognostic (1.19e-1)" "unprognostic (6.43e-2)" "unprognostic (7.15e-2)" "unprognostic (2.77e-1)" "unprognostic (2.44e-1)" RPS15A S15A ENSG00000134419 "Ribosomal protein S15a" P62244 16 18781295-18790383 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Diamond-Blackfan anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Decidual stromal cells: 8260.8;Esophageal suprabasal cells: 7667.6;Extravillous trophoblasts: 7690.1;Gastric progenitor cells: 8414.2;Ovarian stromal cells: 7561.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047103 Supported NA NA 110000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 164 "HPA047103: " "unprognostic (1.65e-2)" "unprognostic (7.65e-3)" "unprognostic (3.81e-1)" "unprognostic (2.80e-3)" "unprognostic (2.73e-1)" "unprognostic (8.67e-2)" "unprognostic (3.30e-2)" "unprognostic (1.08e-1)" "unprognostic (2.93e-3)" "unprognostic (7.83e-2)" "unprognostic (1.39e-1)" "unprognostic (8.54e-2)" "potential prognostic unfavorable (5.21e-4)" "unprognostic (6.97e-3)" "potential prognostic unfavorable (5.80e-5)" "unprognostic (7.93e-2)" "unprognostic (1.25e-2)" "unprognostic (1.57e-1)" "unprognostic (1.09e-1)" "unprognostic (2.07e-1)" "unprognostic (1.62e-2)" "potential prognostic unfavorable (7.12e-4)" "unprognostic (6.99e-3)" "unprognostic (2.31e-1)" "unprognostic (1.68e-3)" "unprognostic (3.25e-1)" "unprognostic (8.38e-3)" "unprognostic (3.31e-3)" "unprognostic (2.84e-1)" "unprognostic (2.13e-1)" "unprognostic (5.50e-3)" RPS16 S16 ENSG00000105193 "Ribosomal protein S16" P62249 19 39433137-39435949 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 6125.9;Esophageal basal cells: 7378.6;Esophageal suprabasal cells: 7900.6;Extravillous trophoblasts: 7252.0;Migrating cytotrophoblasts: 6609.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA064222 Approved Enhanced "Endoplasmic reticulum,Cytosol" No No 37000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 588 "Endoplasmic reticulum, Cytosol" "HPA064222: " "unprognostic (1.52e-1)" "unprognostic (1.23e-3)" "unprognostic (8.24e-2)" "unprognostic (1.04e-1)" "unprognostic (4.46e-1)" "unprognostic (1.04e-3)" "unprognostic (4.59e-2)" "unprognostic (8.09e-3)" "unprognostic (3.86e-2)" "unprognostic (3.57e-1)" "unprognostic (7.21e-3)" "unprognostic (4.07e-2)" "unprognostic (4.66e-3)" "unprognostic (5.74e-3)" "potential prognostic unfavorable (1.70e-5)" "unprognostic (1.06e-3)" "unprognostic (2.39e-2)" "unprognostic (1.44e-1)" "unprognostic (1.19e-2)" "unprognostic (6.54e-3)" "unprognostic (4.38e-2)" "unprognostic (2.19e-2)" "unprognostic (2.50e-2)" "unprognostic (3.64e-2)" "unprognostic (1.01e-1)" "unprognostic (6.99e-2)" "unprognostic (8.30e-2)" "unprognostic (8.75e-2)" "unprognostic (1.84e-1)" "unprognostic (2.29e-1)" "unprognostic (1.83e-1)" RPS17 "MGC72007, RPS17L, RPS17L1, RPS17L2, S17" ENSG00000182774 "Ribosomal protein S17" P08708 15 82536750-82540459 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Diamond-Blackfan anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 1596.6;Enteric stem cells: 3299.6;Enteric transient amplifying cells: 3075.6;Epididymal basal cells: 1934.5;Epididymal clear cells: 1602.4;Epididymal efferent duct absorptive cells: 2148.7;Epididymal principal cells: 2127.1;Gastric chief cells: 3360.2;Goblet cells: 1738.9;Mucous neck cells: 2326.4;Paneth cells: 2258.6;Parietal cells: 2591.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055060 Approved Approved "Nucleoli,Endoplasmic reticulum,Cytosol" NA NA 250000 "Cluster 18: Non-specific - Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 99 "Endoplasmic reticulum, Cytosol" Nucleoli "HPA055060: " "unprognostic (1.43e-2)" "unprognostic (2.24e-2)" "unprognostic (2.43e-1)" "unprognostic (2.21e-2)" "unprognostic (8.17e-3)" "unprognostic (1.22e-1)" "unprognostic (6.22e-2)" "unprognostic (5.31e-3)" "unprognostic (3.14e-1)" "potential prognostic unfavorable (7.42e-4)" "unprognostic (1.76e-1)" "unprognostic (8.26e-3)" "unprognostic (2.94e-2)" "unprognostic (1.16e-3)" "unprognostic (5.23e-3)" "unprognostic (1.50e-2)" "unprognostic (4.42e-1)" "unprognostic (9.71e-2)" "unprognostic (3.31e-1)" "unprognostic (7.45e-3)" "unprognostic (4.42e-2)" "unprognostic (1.47e-1)" "unprognostic (4.04e-2)" "unprognostic (1.26e-1)" "unprognostic (9.97e-2)" "unprognostic (4.71e-1)" "unprognostic (2.91e-1)" "unprognostic (1.52e-1)" "unprognostic (1.53e-1)" RPS18 "D6S218E, HKE3, KE-3, KE3, S18" ENSG00000231500 "Ribosomal protein S18" P62269 6 33272075-33276511 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast secretory cells: 17196.4;Decidual stromal cells: 23140.3;Esophageal apical cells: 17074.5;Esophageal basal cells: 19152.2;Esophageal suprabasal cells: 23955.6;Extravillous trophoblasts: 18013.9;Suprabasal keratinocytes: 21293.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Not detected" "Not detected" "HPA050159, HPA055007" Approved Supported Cytosol NA NA 59000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 71 Cytosol "HPA050159: , HPA055007: " "unprognostic (5.23e-3)" "unprognostic (4.22e-3)" "unprognostic (2.98e-1)" "unprognostic (2.48e-2)" "unprognostic (2.30e-1)" "unprognostic (2.36e-1)" "unprognostic (7.00e-3)" "unprognostic (2.37e-1)" "unprognostic (8.99e-2)" "unprognostic (2.82e-1)" "unprognostic (2.35e-1)" "unprognostic (2.60e-1)" "potential prognostic unfavorable (3.61e-4)" "unprognostic (1.73e-2)" "potential prognostic unfavorable (3.09e-4)" "unprognostic (1.40e-1)" "unprognostic (8.98e-3)" "potential prognostic favorable (9.97e-4)" "unprognostic (2.14e-1)" "unprognostic (3.89e-2)" "unprognostic (7.53e-3)" "unprognostic (5.14e-3)" "unprognostic (3.32e-1)" "unprognostic (1.08e-1)" "potential prognostic favorable (4.64e-4)" "unprognostic (1.04e-1)" "unprognostic (1.83e-1)" "unprognostic (1.28e-2)" "unprognostic (5.02e-1)" "unprognostic (1.10e-1)" "unprognostic (1.30e-1)" RPS19 "DBA, eS19, LOH19CR1, S19" ENSG00000105372 "Ribosomal protein S19" P39019 19 41860255-41872925 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Host-virus interaction" "Ribonucleoprotein, Ribosomal protein" "Diamond-Blackfan anemia, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 10268.9;Esophageal basal cells: 11343.2;Esophageal suprabasal cells: 13540.1;Extravillous trophoblasts: 11782.2;Migrating cytotrophoblasts: 10321.5;Suprabasal keratinocytes: 11649.1" "Cell type enhanced" "Detected in all" "leukocyte: 623.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063217 Supported Nucleoplasm NA NA 37000 "Cluster 18: Non-specific - Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 344 Nucleoplasm "HPA063217: " "unprognostic (2.02e-2)" "unprognostic (9.00e-3)" "unprognostic (1.72e-1)" "unprognostic (2.47e-2)" "unprognostic (1.34e-1)" "unprognostic (2.62e-2)" "unprognostic (2.76e-3)" "unprognostic (2.34e-1)" "unprognostic (5.69e-2)" "unprognostic (8.20e-2)" "unprognostic (2.15e-3)" "unprognostic (3.12e-3)" "potential prognostic unfavorable (6.05e-4)" "unprognostic (4.74e-2)" "unprognostic (1.19e-3)" "unprognostic (2.67e-3)" "unprognostic (4.18e-2)" "unprognostic (2.72e-2)" "unprognostic (9.48e-2)" "unprognostic (5.40e-2)" "unprognostic (1.09e-2)" "unprognostic (2.48e-2)" "unprognostic (2.69e-1)" "unprognostic (1.17e-1)" "unprognostic (1.27e-1)" "unprognostic (7.60e-2)" "unprognostic (1.31e-1)" "unprognostic (2.44e-1)" "unprognostic (2.54e-1)" "unprognostic (2.44e-1)" "unprognostic (1.30e-1)" RPS19BP1 "FLJ21770, MGC52010" ENSG00000187051 "Ribosomal protein S19 binding protein 1" Q86WX3 22 39529093-39532761 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042874 Uncertain Supported Nucleoplasm,Nucleoli,Cytosol NA Yes "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 97: Non-specific - Cellular respiration" 31 Nucleoli "Nucleoplasm, Cytosol" "HPA042874: " "unprognostic (3.95e-1)" "unprognostic (1.48e-1)" "unprognostic (2.86e-1)" "unprognostic (3.49e-1)" "unprognostic (4.45e-2)" "unprognostic (2.35e-1)" "unprognostic (4.45e-2)" "unprognostic (2.70e-1)" "unprognostic (2.14e-1)" "unprognostic (9.28e-3)" "unprognostic (7.60e-2)" "unprognostic (3.88e-2)" "unprognostic (2.41e-2)" "potential prognostic unfavorable (1.12e-4)" "unprognostic (2.75e-3)" "unprognostic (3.31e-2)" "unprognostic (2.31e-1)" "unprognostic (1.52e-2)" "unprognostic (1.35e-1)" "unprognostic (2.40e-1)" "unprognostic (3.14e-1)" "unprognostic (2.58e-1)" "unprognostic (1.96e-1)" "unprognostic (1.23e-1)" "unprognostic (8.52e-2)" "unprognostic (5.63e-2)" "unprognostic (3.17e-1)" "unprognostic (2.07e-1)" "unprognostic (1.36e-1)" "unprognostic (2.32e-1)" "unprognostic (1.57e-1)" RPS2 "LLREP3, S2" ENSG00000140988 "Ribosomal protein S2" P15880 16 1962058-1964841 "Cancer-related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Decidual stromal cells: 15996.7;Esophageal basal cells: 15789.8;Esophageal suprabasal cells: 15705.1;Extravillous trophoblasts: 16997.5;Migrating cytotrophoblasts: 13210.2;Suprabasal keratinocytes: 10680.1" "Cell type enhanced" "Detected in all" "leukocyte: 451.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" HPA055133 Approved Approved "Endoplasmic reticulum,Cytosol" NA NA 580000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 348 "Endoplasmic reticulum, Cytosol" "HPA055133: " "potential prognostic unfavorable (9.52e-4)" "unprognostic (8.19e-2)" "unprognostic (1.62e-1)" "unprognostic (1.22e-3)" "unprognostic (1.12e-1)" "unprognostic (2.09e-2)" "unprognostic (9.92e-2)" "unprognostic (4.86e-2)" "unprognostic (5.25e-3)" "unprognostic (3.99e-2)" "validated prognostic unfavorable (4.55e-6)" "validated prognostic unfavorable (3.68e-4)" "unprognostic (1.04e-3)" "validated prognostic unfavorable (6.20e-6)" "validated prognostic unfavorable (2.96e-5)" "unprognostic (1.76e-3)" "potential prognostic unfavorable (7.31e-4)" "unprognostic (7.87e-2)" "unprognostic (4.46e-1)" "unprognostic (8.03e-3)" "unprognostic (1.55e-1)" "unprognostic (7.88e-3)" "unprognostic (1.24e-1)" "unprognostic (1.05e-1)" "unprognostic (1.60e-1)" "unprognostic (2.46e-1)" "unprognostic (5.95e-2)" "unprognostic (3.23e-1)" "unprognostic (3.44e-1)" "unprognostic (1.98e-1)" "unprognostic (1.11e-1)" RPS20 "S20, uS10" ENSG00000008988 "Ribosomal protein S20" P60866 8 56067254-56074510 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 5020.0;Esophageal suprabasal cells: 5362.1;Extravillous trophoblasts: 5125.0;Ovarian stromal cells: 4958.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003570 Approved Supported "Endoplasmic reticulum,Cytosol" NA NA 75000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 197 "Endoplasmic reticulum, Cytosol" "HPA003570: " "unprognostic (4.91e-3)" "unprognostic (1.78e-1)" "unprognostic (2.70e-1)" "unprognostic (2.96e-2)" "unprognostic (1.22e-1)" "potential prognostic unfavorable (1.87e-4)" "unprognostic (8.68e-2)" "unprognostic (5.75e-2)" "unprognostic (1.01e-1)" "unprognostic (2.55e-1)" "potential prognostic unfavorable (5.55e-4)" "unprognostic (7.48e-3)" "unprognostic (3.00e-2)" "unprognostic (4.92e-2)" "unprognostic (1.59e-3)" "unprognostic (6.12e-2)" "unprognostic (6.72e-2)" "unprognostic (9.74e-2)" "unprognostic (2.90e-2)" "unprognostic (2.56e-1)" "unprognostic (3.32e-2)" "unprognostic (8.77e-3)" "unprognostic (2.39e-2)" "unprognostic (2.86e-1)" "unprognostic (2.28e-1)" "unprognostic (3.23e-2)" "unprognostic (9.47e-2)" "unprognostic (1.41e-2)" "unprognostic (1.82e-1)" "unprognostic (4.28e-2)" "unprognostic (1.64e-1)" RPS21 S21 ENSG00000171858 "Ribosomal protein S21" P63220 20 62387103-62388520 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric progenitor cells: 5380.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003371 Approved Supported "Endoplasmic reticulum,Cytosol" NA NA 59000 "Cluster 24: Non-specific - Transcription" "Cluster 54: Non-specific - Ribosome" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 95 "Endoplasmic reticulum, Cytosol" "HPA003371: " "unprognostic (1.27e-2)" "unprognostic (2.77e-2)" "unprognostic (3.81e-2)" "unprognostic (1.32e-3)" "unprognostic (4.83e-2)" "unprognostic (2.62e-1)" "unprognostic (2.09e-1)" "unprognostic (3.09e-1)" "unprognostic (1.12e-1)" "unprognostic (2.04e-1)" "unprognostic (1.95e-1)" "unprognostic (2.34e-3)" "unprognostic (1.28e-3)" "validated prognostic unfavorable (2.97e-6)" "validated prognostic unfavorable (1.28e-6)" "unprognostic (1.92e-1)" "unprognostic (3.13e-1)" "unprognostic (2.15e-2)" "unprognostic (2.01e-1)" "unprognostic (2.31e-1)" "unprognostic (2.82e-1)" "unprognostic (2.62e-1)" "unprognostic (3.68e-2)" "unprognostic (2.61e-1)" "unprognostic (3.79e-3)" "unprognostic (2.46e-3)" "unprognostic (6.59e-2)" "unprognostic (1.52e-1)" "unprognostic (2.11e-1)" "unprognostic (1.01e-1)" "unprognostic (4.28e-2)" RPS23 "S23, uS12" ENSG00000186468 "Ribosomal protein S23" P62266 5 82273320-82278396 "Disease related genes, Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Deafness, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal suprabasal cells: 8104.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Not detected" "Not detected" "HPA054853, HPA071639" Approved Supported "Endoplasmic reticulum,Cytosol" NA NA 530000 "Cluster 18: Non-specific - Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 151 Cytosol "Endoplasmic reticulum" "HPA054853: , HPA071639: " "unprognostic (6.22e-3)" "unprognostic (4.07e-2)" "unprognostic (2.17e-1)" "unprognostic (6.06e-3)" "unprognostic (2.64e-1)" "unprognostic (3.06e-2)" "unprognostic (2.57e-1)" "unprognostic (4.39e-2)" "unprognostic (4.82e-3)" "unprognostic (2.15e-2)" "potential prognostic favorable (2.94e-5)" "unprognostic (3.29e-3)" "potential prognostic unfavorable (8.73e-4)" "validated prognostic unfavorable (9.16e-5)" "validated prognostic unfavorable (8.33e-4)" "unprognostic (5.37e-2)" "unprognostic (1.98e-1)" "unprognostic (7.92e-2)" "unprognostic (1.71e-1)" "unprognostic (3.15e-2)" "unprognostic (1.02e-3)" "unprognostic (6.16e-2)" "unprognostic (9.27e-2)" "unprognostic (1.15e-1)" "potential prognostic favorable (6.24e-4)" "unprognostic (1.47e-1)" "unprognostic (4.60e-2)" "unprognostic (2.60e-3)" "unprognostic (4.42e-1)" "unprognostic (1.52e-1)" "unprognostic (4.68e-2)" RPS24 "eS24, S24" ENSG00000138326 "Ribosomal protein S24" P62847 10 78033760-78056813 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Diamond-Blackfan anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal suprabasal cells: 8920.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA003364, HPA073508" Approved Enhanced "Endoplasmic reticulum,Cytosol" NA NA 29000 "Cluster 30: Non-specific - DNA binding" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 142 "Endoplasmic reticulum, Cytosol" "HPA003364: , HPA073508: " "unprognostic (1.75e-2)" "unprognostic (1.58e-3)" "unprognostic (1.08e-1)" "unprognostic (3.51e-2)" "unprognostic (5.46e-2)" "unprognostic (3.84e-2)" "unprognostic (8.45e-2)" "unprognostic (1.26e-3)" "unprognostic (1.00e-2)" "unprognostic (1.80e-1)" "unprognostic (4.36e-3)" "unprognostic (1.85e-1)" "potential prognostic unfavorable (3.80e-4)" "unprognostic (2.60e-2)" "unprognostic (2.61e-3)" "unprognostic (1.64e-2)" "unprognostic (1.79e-2)" "unprognostic (6.96e-3)" "unprognostic (5.12e-2)" "unprognostic (1.30e-1)" "unprognostic (5.36e-3)" "unprognostic (1.31e-2)" "unprognostic (8.79e-2)" "unprognostic (1.28e-1)" "unprognostic (1.14e-1)" "unprognostic (1.16e-1)" "unprognostic (9.00e-2)" "unprognostic (2.32e-1)" "unprognostic (2.44e-1)" "unprognostic (2.95e-2)" "unprognostic (1.30e-1)" RPS25 S25 ENSG00000118181 "Ribosomal protein S25" P62851 11 119015712-119018691 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Enteric stem cells: 3021.1;Epididymal efferent duct absorptive cells: 3610.7;Gastric chief cells: 3153.8;Ovarian stromal cells: 3254.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031801, HPA078683" Approved Supported "Nucleoli,Endoplasmic reticulum,Cytosol" NA NA 47000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 156 "Endoplasmic reticulum, Cytosol" Nucleoli "HPA031801: , HPA078683: " "unprognostic (1.24e-2)" "unprognostic (4.62e-2)" "unprognostic (3.35e-2)" "unprognostic (6.84e-3)" "unprognostic (1.74e-1)" "unprognostic (2.00e-2)" "unprognostic (1.55e-1)" "unprognostic (4.76e-2)" "unprognostic (2.39e-3)" "unprognostic (1.26e-1)" "unprognostic (9.02e-2)" "unprognostic (4.89e-2)" "unprognostic (1.46e-2)" "unprognostic (2.43e-3)" "potential prognostic unfavorable (8.08e-4)" "unprognostic (3.62e-2)" "unprognostic (5.44e-3)" "unprognostic (5.80e-3)" "unprognostic (1.33e-1)" "unprognostic (1.01e-2)" "unprognostic (1.04e-1)" "unprognostic (1.00e-2)" "unprognostic (6.40e-2)" "unprognostic (6.50e-2)" "unprognostic (7.75e-3)" "unprognostic (2.98e-1)" "unprognostic (1.87e-2)" "unprognostic (1.02e-1)" "unprognostic (4.95e-1)" "unprognostic (5.17e-2)" "unprognostic (1.87e-1)" RPS26 "eS26, S26" ENSG00000197728 "Ribosomal protein S26" P62854 12 56041351-56044697 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Diamond-Blackfan anemia, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epididymal efferent duct absorptive cells: 2794.7;Esophageal apical cells: 2535.0;Esophageal suprabasal cells: 2576.5;Extravillous trophoblasts: 2739.5;Gastric progenitor cells: 3108.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043961, HPA055803" Uncertain Enhanced "Nucleoli,Endoplasmic reticulum,Cytosol" NA NA 31000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 70: Non-specific - Protein processing" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 137 "Endoplasmic reticulum, Cytosol" Nucleoli "HPA043961: , HPA055803: " "unprognostic (4.40e-3)" "unprognostic (1.66e-2)" "unprognostic (1.54e-1)" "unprognostic (1.66e-2)" "unprognostic (1.91e-1)" "unprognostic (3.46e-1)" "unprognostic (2.37e-1)" "unprognostic (2.71e-1)" "unprognostic (2.68e-1)" "unprognostic (1.72e-1)" "unprognostic (4.08e-2)" "unprognostic (1.08e-2)" "unprognostic (1.92e-2)" "unprognostic (3.55e-2)" "potential prognostic unfavorable (4.96e-4)" "unprognostic (5.48e-3)" "unprognostic (1.50e-3)" "unprognostic (1.77e-2)" "unprognostic (2.81e-3)" "unprognostic (1.33e-1)" "unprognostic (1.67e-1)" "unprognostic (4.11e-2)" "unprognostic (6.42e-2)" "unprognostic (1.33e-1)" "unprognostic (6.53e-2)" "unprognostic (3.46e-1)" "unprognostic (1.45e-1)" "unprognostic (2.85e-1)" "unprognostic (1.73e-1)" "unprognostic (2.67e-1)" "unprognostic (1.17e-1)" RPS27 "MPS-1, MPS1, S27" ENSG00000177954 "Ribosomal protein S27" P42677 1 153990762-153992155 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Diamond-Blackfan anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 13568.9;Ovarian stromal cells: 12431.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Group enriched" "Detected in many" 4 "amygdala: 24.1;basal ganglia: 11.7;cerebral cortex: 27.0;hippocampal formation: 25.2" HPA066851 Approved "Nucleoli,Endoplasmic reticulum,Cytosol" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 75 "Endoplasmic reticulum, Cytosol" Nucleoli "HPA066851: " "unprognostic (4.15e-2)" "unprognostic (6.17e-3)" "unprognostic (1.23e-1)" "unprognostic (8.13e-3)" "unprognostic (2.79e-1)" "unprognostic (2.58e-1)" "unprognostic (3.15e-2)" "unprognostic (4.23e-3)" "unprognostic (8.95e-2)" "unprognostic (1.70e-1)" "unprognostic (1.67e-2)" "unprognostic (1.72e-1)" "potential prognostic unfavorable (3.81e-5)" "unprognostic (1.01e-2)" "unprognostic (3.12e-2)" "unprognostic (7.65e-2)" "unprognostic (2.13e-1)" "potential prognostic favorable (2.07e-4)" "unprognostic (2.96e-1)" "unprognostic (5.35e-2)" "potential prognostic unfavorable (3.76e-5)" "unprognostic (3.54e-2)" "unprognostic (3.77e-1)" "unprognostic (7.19e-3)" "unprognostic (2.36e-1)" "unprognostic (1.76e-2)" "unprognostic (1.38e-1)" "unprognostic (4.78e-2)" "unprognostic (1.53e-1)" "unprognostic (1.49e-1)" "unprognostic (1.82e-1)" RPS27A "S27A, Uba80, UBCEP80" ENSG00000143947 "Ribosomal protein S27a" P62979 2 55231903-55235853 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal basal cells: 10094.9;Esophageal suprabasal cells: 10806.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "CAB033319, HPA041344, HPA049132, HPA054087" Supported Supported "Nucleoli,Endoplasmic reticulum,Cytosol,Acrosome,Equatorial segment" NA Yes 170000000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 85 "Nucleoli, Endoplasmic reticulum, Cytosol" "Acrosome, Equatorial segment" "CAB033319: , HPA041344: , HPA049132: , HPA054087: " "unprognostic (5.75e-2)" "unprognostic (2.57e-2)" "unprognostic (1.29e-2)" "unprognostic (6.31e-2)" "unprognostic (6.42e-2)" "unprognostic (1.47e-1)" "unprognostic (6.79e-2)" "unprognostic (7.12e-2)" "unprognostic (1.73e-2)" "unprognostic (2.09e-1)" "potential prognostic favorable (3.24e-4)" "unprognostic (1.92e-1)" "unprognostic (2.50e-2)" "validated prognostic unfavorable (3.91e-4)" "validated prognostic unfavorable (3.59e-6)" "unprognostic (1.94e-2)" "unprognostic (6.67e-2)" "unprognostic (4.94e-3)" "unprognostic (2.69e-2)" "unprognostic (2.12e-1)" "unprognostic (1.06e-2)" "unprognostic (1.03e-1)" "unprognostic (5.17e-2)" "unprognostic (2.93e-1)" "unprognostic (4.80e-3)" "unprognostic (1.13e-1)" "unprognostic (7.44e-2)" "unprognostic (2.70e-1)" "unprognostic (2.22e-1)" "unprognostic (2.05e-1)" "unprognostic (2.52e-2)" RPS27L ENSG00000185088 "Ribosomal protein S27 like" Q71UM5 15 63125872-63158021 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Enterocytes: 1291.9;Extravillous trophoblasts: 1858.6;Gastric chief cells: 997.0;Gastric progenitor cells: 938.2;Hepatocytes: 1069.0;Parietal cells: 1447.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" HPA066851 Supported "Nucleoli,Endoplasmic reticulum,Cytosol" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 70: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 40: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 22 "Endoplasmic reticulum, Cytosol" Nucleoli "HPA066851: " "unprognostic (2.17e-3)" "unprognostic (9.36e-2)" "unprognostic (6.81e-2)" "unprognostic (8.70e-2)" "unprognostic (2.83e-2)" "unprognostic (3.20e-2)" "unprognostic (1.54e-1)" "unprognostic (5.03e-2)" "unprognostic (1.41e-1)" "unprognostic (1.12e-1)" "unprognostic (2.97e-2)" "unprognostic (8.80e-2)" "unprognostic (1.79e-3)" "unprognostic (5.80e-3)" "unprognostic (2.05e-2)" "unprognostic (3.04e-1)" "unprognostic (5.89e-2)" "unprognostic (6.54e-2)" "unprognostic (3.74e-2)" "unprognostic (3.00e-1)" "unprognostic (2.32e-2)" "potential prognostic unfavorable (4.81e-4)" "unprognostic (2.10e-1)" "unprognostic (4.23e-2)" "unprognostic (5.96e-2)" "unprognostic (2.76e-1)" "unprognostic (7.12e-2)" "unprognostic (1.51e-1)" "unprognostic (1.54e-1)" "potential prognostic favorable (2.11e-4)" "unprognostic (1.69e-2)" RPS28 "eS28, S28" ENSG00000233927 "Ribosomal protein S28" P62857 19 8321158-8323340 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Diamond-Blackfan anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Breast secretory cells: 7410.0;Gastric chief cells: 9108.8;Parietal cells: 7046.8" "Cell type enhanced" "Detected in all" "leukocyte: 831.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047132 Approved Approved Cytosol NA NA 1000000 "Cluster 13: Non-specific - Mitochondria" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 113 Cytosol "HPA047132: " "unprognostic (6.63e-2)" "unprognostic (1.58e-2)" "unprognostic (2.23e-1)" "unprognostic (4.56e-3)" "unprognostic (1.06e-1)" "unprognostic (1.83e-2)" "unprognostic (5.63e-2)" "potential prognostic favorable (1.46e-4)" "unprognostic (6.26e-2)" "unprognostic (1.18e-1)" "potential prognostic favorable (1.47e-5)" "unprognostic (7.57e-2)" "unprognostic (2.10e-2)" "unprognostic (2.18e-1)" "potential prognostic unfavorable (2.64e-6)" "unprognostic (7.16e-2)" "unprognostic (4.75e-2)" "unprognostic (3.26e-1)" "unprognostic (2.11e-1)" "unprognostic (5.88e-2)" "unprognostic (1.75e-1)" "unprognostic (8.82e-3)" "unprognostic (5.48e-3)" "unprognostic (2.42e-2)" "unprognostic (9.84e-2)" "unprognostic (8.50e-2)" "unprognostic (1.20e-2)" "unprognostic (9.51e-2)" "unprognostic (1.75e-1)" "unprognostic (4.51e-2)" "unprognostic (3.04e-1)" RPS29 "S29, uS14" ENSG00000213741 "Ribosomal protein S29" P62273 14 49570984-49599164 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Diamond-Blackfan anemia, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Enteric stem cells: 7439.5;Enteric transient amplifying cells: 7357.0;Gastric chief cells: 6581.8;Goblet cells: 6552.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004107 Enhanced Supported "Endoplasmic reticulum,Cytosol" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 34 "Endoplasmic reticulum, Cytosol" "HPA004107: " "unprognostic (2.38e-3)" "potential prognostic favorable (5.18e-4)" "unprognostic (1.15e-1)" "potential prognostic favorable (4.15e-4)" "unprognostic (1.68e-1)" "unprognostic (3.01e-2)" "unprognostic (2.68e-2)" "unprognostic (5.16e-2)" "unprognostic (3.24e-2)" "unprognostic (1.81e-1)" "potential prognostic favorable (5.97e-6)" "unprognostic (4.13e-1)" "unprognostic (6.01e-3)" "unprognostic (1.26e-2)" "potential prognostic unfavorable (8.67e-4)" "unprognostic (2.75e-1)" "unprognostic (1.45e-1)" "unprognostic (3.49e-3)" "unprognostic (6.79e-2)" "unprognostic (2.30e-1)" "unprognostic (2.16e-1)" "unprognostic (5.53e-3)" "unprognostic (1.53e-1)" "unprognostic (8.59e-2)" "unprognostic (5.23e-2)" "unprognostic (2.09e-1)" "unprognostic (8.73e-2)" "unprognostic (4.88e-2)" "unprognostic (4.28e-1)" "unprognostic (3.12e-2)" "unprognostic (4.01e-1)" RPS3 "FLJ26283, FLJ27450, MGC87870, S3" ENSG00000149273 "Ribosomal protein S3" P23396 11 75399515-75422280 "Cancer-related genes, Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Apoptosis, Cell cycle, Cell division, DNA damage, DNA repair, Mitosis, Transcription, Transcription regulation, Translation regulation" "DNA-binding, Lyase, Ribonucleoprotein, Ribosomal protein, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 10162.1;Esophageal basal cells: 11756.5;Esophageal suprabasal cells: 11421.4;Extravillous trophoblasts: 10717.4;Migrating cytotrophoblasts: 9811.6" "Cell type enhanced" "Detected in all" "leukocyte: 412.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" HPA063339 Uncertain Supported "Endoplasmic reticulum,Cytosol" NA NA 660000 "Cluster 33: Non-specific - ATP binding" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 261 "Endoplasmic reticulum, Cytosol" "HPA063339: " "unprognostic (5.68e-2)" "unprognostic (9.90e-3)" "unprognostic (3.54e-1)" "unprognostic (1.33e-2)" "unprognostic (1.35e-1)" "unprognostic (1.95e-1)" "unprognostic (2.62e-2)" "unprognostic (8.73e-2)" "unprognostic (3.53e-3)" "unprognostic (5.29e-2)" "potential prognostic favorable (5.49e-5)" "unprognostic (1.29e-3)" "unprognostic (2.15e-3)" "unprognostic (5.91e-3)" "potential prognostic unfavorable (2.17e-6)" "unprognostic (7.33e-2)" "unprognostic (1.08e-1)" "unprognostic (2.51e-2)" "unprognostic (4.59e-2)" "unprognostic (2.40e-2)" "unprognostic (1.24e-1)" "unprognostic (2.60e-2)" "unprognostic (2.86e-1)" "unprognostic (6.92e-3)" "potential prognostic favorable (1.03e-5)" "unprognostic (1.47e-1)" "unprognostic (3.30e-1)" "unprognostic (2.99e-1)" "unprognostic (2.67e-1)" "unprognostic (3.18e-1)" "unprognostic (1.50e-2)" RPS3A "MFTL, S3A" ENSG00000145425 "Ribosomal protein S3A" P61247 4 151099624-151104642 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" Differentiation "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Decidual stromal cells: 8451.6;Esophageal suprabasal cells: 8044.3;Extravillous trophoblasts: 7545.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047100, HPA053454" Approved Enhanced "Nucleoli,Endoplasmic reticulum,Cytosol" No No 270000 "Cluster 24: Non-specific - Transcription" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 224 "Nucleoli, Endoplasmic reticulum, Cytosol" "HPA047100: , HPA053454: " "unprognostic (9.99e-3)" "unprognostic (1.73e-2)" "unprognostic (1.88e-2)" "unprognostic (1.27e-2)" "unprognostic (3.32e-1)" "unprognostic (6.33e-2)" "unprognostic (6.99e-2)" "unprognostic (3.43e-1)" "unprognostic (3.93e-2)" "unprognostic (1.05e-1)" "validated prognostic favorable (7.18e-6)" "validated prognostic favorable (5.96e-4)" "unprognostic (4.85e-2)" "potential prognostic unfavorable (4.66e-4)" "unprognostic (1.43e-2)" "unprognostic (2.44e-1)" "unprognostic (9.72e-3)" "unprognostic (6.65e-2)" "unprognostic (8.15e-3)" "unprognostic (2.10e-2)" "unprognostic (2.17e-3)" "unprognostic (1.43e-2)" "unprognostic (2.00e-2)" "unprognostic (2.50e-1)" "unprognostic (4.00e-3)" "unprognostic (2.45e-1)" "unprognostic (1.29e-1)" "unprognostic (2.07e-1)" "unprognostic (4.40e-1)" "unprognostic (1.76e-1)" "unprognostic (4.29e-2)" RPS4X "CCG2, DXS306, FLJ40595, RPS4, S4, SCAR, SCR10" ENSG00000198034 "Ribosomal protein S4 X-linked" P62701 X 72255679-72277248 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Breast secretory cells: 10089.1;Decidual stromal cells: 13757.0;Esophageal basal cells: 10837.1;Esophageal suprabasal cells: 12383.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000857 Supported NA NA 230000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 209 "HPA000857: " "unprognostic (1.21e-2)" "unprognostic (3.25e-2)" "unprognostic (3.06e-1)" "unprognostic (3.45e-3)" "unprognostic (1.57e-1)" "unprognostic (3.34e-1)" "unprognostic (1.60e-2)" "unprognostic (2.57e-1)" "unprognostic (1.03e-3)" "unprognostic (6.96e-2)" "unprognostic (3.14e-1)" "unprognostic (2.96e-1)" "potential prognostic unfavorable (4.65e-4)" "unprognostic (1.49e-2)" "potential prognostic unfavorable (6.05e-6)" "unprognostic (1.03e-1)" "unprognostic (4.68e-2)" "unprognostic (2.22e-2)" "unprognostic (1.17e-1)" "unprognostic (7.44e-3)" "unprognostic (3.42e-1)" "unprognostic (2.82e-1)" "unprognostic (8.66e-3)" "unprognostic (4.56e-2)" "unprognostic (6.90e-2)" "unprognostic (1.05e-1)" "unprognostic (4.42e-2)" "unprognostic (1.28e-2)" "unprognostic (5.70e-2)" "unprognostic (3.54e-2)" "unprognostic (1.71e-2)" RPS4Y1 "MGC119100, MGC5070, RPS4Y, S4" ENSG00000129824 "Ribosomal protein S4 Y-linked 1" P22090 Y 2841602-2932000 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 627.1;Epididymal basal cells: 1214.7;Epididymal efferent duct absorptive cells: 1345.2;Epididymal principal cells: 1040.3;Gastric chief cells: 821.2;Migrating cytotrophoblasts: 663.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 616.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" HPA000857 Approved NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 31 "HPA000857: " "unprognostic (4.58e-1)" "unprognostic (1.63e-3)" "unprognostic (3.01e-2)" "unprognostic (6.65e-2)" "unprognostic (3.01e-1)" "unprognostic (1.71e-2)" "unprognostic (1.84e-3)" "unprognostic (3.42e-1)" "unprognostic (2.55e-2)" "unprognostic (1.65e-1)" "unprognostic (4.13e-2)" "unprognostic (2.52e-2)" "unprognostic (1.30e-2)" "unprognostic (4.63e-2)" "unprognostic (4.53e-2)" "unprognostic (4.21e-2)" "unprognostic (1.16e-1)" "unprognostic (3.80e-2)" "unprognostic (2.78e-2)" "unprognostic (2.69e-1)" "unprognostic (4.45e-2)" "unprognostic (4.90e-3)" "unprognostic (5.05e-2)" "unprognostic (1.43e-2)" "unprognostic (4.14e-1)" "unprognostic (1.30e-2)" RPS4Y2 RPS4Y2P ENSG00000280969 "Ribosomal protein S4 Y-linked 2" Q8TD47 Y 20756108-20781032 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "prostate: 1.8;testis: 1.0" "Group enriched" "Detected in some" 6 "B-cells: 2.6;Differentiating spermatogonia: 2.5;Early primary spermatocytes: 1.7;Prostatic glandular cells: 1.2;Undifferentiated spermatogonia: 2.2" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "Prostate Adenocarcinoma (TCGA): 2.7" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 6 "neutrophil: 7.4" "Lineage enriched" "Detected in many" 6 "granulocytes: 7.4" "Not detected" "Not detected" "Prostate - Prostate glandular cells" HPA000857 Uncertain NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 21: Testis - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 44 "HPA000857: " "unprognostic (4.16e-1)" RPS5 S5 ENSG00000083845 "Ribosomal protein S5" P46782 19 58386400-58394806 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Decidual stromal cells: 5984.2;Esophageal apical cells: 6054.7;Esophageal basal cells: 6655.4;Esophageal suprabasal cells: 7373.8;Pancreatic acinar cells: 5868.6" "Cell type enhanced" "Detected in all" "leukocyte: 253.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055878, HPA061979" Enhanced Supported "Endoplasmic reticulum,Cytosol" NA NA 540000 "Cluster 18: Non-specific - Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 168 "Endoplasmic reticulum, Cytosol" "HPA055878: , HPA061979: " "unprognostic (1.45e-1)" "unprognostic (5.24e-2)" "unprognostic (1.66e-2)" "unprognostic (3.33e-1)" "unprognostic (1.71e-1)" "unprognostic (5.22e-3)" "unprognostic (7.24e-2)" "unprognostic (5.08e-2)" "unprognostic (5.98e-2)" "unprognostic (2.30e-1)" "unprognostic (1.20e-3)" "unprognostic (2.24e-1)" "unprognostic (1.05e-3)" "validated prognostic unfavorable (1.28e-5)" "validated prognostic unfavorable (5.82e-10)" "unprognostic (3.19e-2)" "unprognostic (1.21e-2)" "unprognostic (1.27e-1)" "unprognostic (5.78e-2)" "unprognostic (1.99e-1)" "unprognostic (8.66e-2)" "unprognostic (2.29e-1)" "unprognostic (2.35e-2)" "unprognostic (2.60e-1)" "unprognostic (1.24e-2)" "unprognostic (8.40e-2)" "unprognostic (2.90e-1)" "unprognostic (6.10e-3)" "unprognostic (7.46e-2)" "unprognostic (8.12e-2)" "unprognostic (1.12e-1)" RPS6 S6 ENSG00000137154 "Ribosomal protein S6" P62753 9 19375715-19380236 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Decidual stromal cells: 13221.0;Esophageal basal cells: 14205.9;Esophageal suprabasal cells: 15354.0;Extravillous trophoblasts: 11768.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004027, HPA031153" Approved Enhanced "Endoplasmic reticulum,Cytosol" NA NA 640000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 514 "Endoplasmic reticulum, Cytosol" "CAB004027: , HPA031153: " "unprognostic (2.57e-2)" "unprognostic (7.01e-3)" "unprognostic (1.73e-1)" "unprognostic (1.71e-1)" "unprognostic (3.43e-1)" "unprognostic (6.23e-2)" "unprognostic (1.24e-1)" "unprognostic (2.86e-2)" "unprognostic (3.27e-2)" "unprognostic (2.92e-1)" "unprognostic (2.25e-2)" "unprognostic (1.58e-1)" "unprognostic (1.71e-2)" "potential prognostic unfavorable (8.93e-4)" "unprognostic (1.58e-3)" "unprognostic (1.03e-1)" "unprognostic (1.57e-2)" "unprognostic (2.92e-2)" "unprognostic (3.87e-2)" "unprognostic (2.92e-1)" "unprognostic (3.07e-1)" "unprognostic (2.84e-1)" "unprognostic (1.65e-1)" "unprognostic (2.64e-1)" "unprognostic (8.87e-2)" "unprognostic (2.19e-1)" "unprognostic (1.31e-1)" "unprognostic (2.94e-1)" "unprognostic (1.75e-1)" "unprognostic (2.68e-2)" "unprognostic (1.01e-2)" RPS6KA1 "HU-1, MAPKAPK1, p90Rsk, RSK1" ENSG00000117676 "Ribosomal protein S6 kinase A1" Q15418 1 26529761-26575030 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Host-virus interaction, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 14.6;Distal convoluted tubule cells: 18.4;Loop of henle epithelial cells: 19.3;Microglia: 80.3;Oligodendrocytes: 15.1;Papillary tip epithelial cells: 17.9;Proximal tubule cells: 33.8;Renal collecting duct intercalated cells: 23.8;Renal collecting duct principal cells: 19.4;Renal connecting tubule cells: 29.9" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 100.2;leukocyte: 62.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Breast glandular cells, Pituitary gland - Corticotropes, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003852, HPA007981" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 37: Non-specific - mRNA processing" "Cluster 102: Non-specific - Mixed function" 41 Cytosol Nucleoplasm "CAB003852: , HPA007981: " "unprognostic (3.63e-1)" "unprognostic (3.43e-2)" "unprognostic (2.32e-1)" "unprognostic (1.19e-2)" "unprognostic (2.40e-3)" "unprognostic (8.88e-3)" "unprognostic (3.57e-1)" "unprognostic (4.83e-2)" "unprognostic (1.96e-1)" "unprognostic (1.41e-2)" "unprognostic (2.56e-3)" "unprognostic (1.80e-1)" "potential prognostic favorable (4.65e-6)" "unprognostic (2.67e-2)" "unprognostic (7.12e-2)" "unprognostic (1.60e-3)" "unprognostic (5.94e-2)" "unprognostic (5.30e-3)" "unprognostic (4.27e-1)" "unprognostic (5.84e-3)" "unprognostic (3.08e-1)" "unprognostic (6.90e-3)" "unprognostic (5.00e-2)" "unprognostic (1.41e-1)" "unprognostic (4.22e-1)" "unprognostic (4.13e-2)" "unprognostic (5.42e-2)" "unprognostic (4.89e-3)" "unprognostic (3.42e-1)" "unprognostic (1.53e-1)" "unprognostic (1.61e-2)" RPS6KA2 "HU-2, RSK3" ENSG00000071242 "Ribosomal protein S6 kinase A2" Q15349 6 166409364-166906451 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 504.9;Astrocytes: 833.4;Bergmann glia: 1046.9;Brain inhibitory neurons: 493.0;Lactotrophs: 1054.7;Retinal horizontal cells: 705.2;Somatotrophs: 986.1;Thyrotrophs: 1044.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "eosinophil: 22.4" "Lineage enriched" "Detected in many" 5 "granulocytes: 22.4" "Low cancer specificity" "Detected in many" "Breast - Adipocytes (Breast), Skin - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026243, HPA045061, HPA054237, CAB069428" Approved Supported Nucleoplasm NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 27: Non-specific - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 16 Nucleoplasm "CAB026243: , CAB069428: , HPA045061: , HPA054237: " "unprognostic (5.39e-3)" "unprognostic (9.86e-2)" "unprognostic (2.53e-1)" "unprognostic (5.47e-2)" "unprognostic (1.03e-1)" "unprognostic (1.35e-1)" "unprognostic (2.34e-1)" "unprognostic (2.48e-2)" "unprognostic (2.04e-1)" "unprognostic (3.97e-3)" "potential prognostic favorable (3.24e-9)" "unprognostic (1.26e-3)" "potential prognostic favorable (4.40e-4)" "unprognostic (1.03e-2)" "potential prognostic favorable (9.26e-4)" "unprognostic (1.19e-1)" "unprognostic (6.83e-3)" "unprognostic (1.62e-1)" "unprognostic (7.83e-2)" "potential prognostic unfavorable (1.75e-4)" "unprognostic (1.48e-2)" "unprognostic (1.33e-1)" "unprognostic (1.82e-3)" "unprognostic (3.19e-2)" "unprognostic (1.74e-1)" "unprognostic (9.94e-2)" "unprognostic (2.59e-1)" "unprognostic (2.41e-3)" "unprognostic (2.40e-1)" "unprognostic (2.15e-2)" "unprognostic (1.17e-2)" RPS6KA3 "CLS, HU-3, MRX19, RSK2" ENSG00000177189 "Ribosomal protein S6 kinase A3" P51812 X 20149911-20267519 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Innate lymphoid cells: 586.0;Neutrophils: 1334.8;Ocular epithelial cells: 574.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003221, CAB003853, CAB013520" Approved Supported Nucleoplasm,Nucleoli,Vesicles,Cytosol No No 6700 "Cluster 41: Basophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 2: Neurons - Nucleosome" "Cluster 18: Liver cancer - Metabolism" "Cluster 24: Neutrophils - Innate immunity signal integration" 48 Nucleoplasm "Nucleoli, Vesicles, Cytosol" "CAB003853: , CAB013520: , HPA003221: " "unprognostic (7.49e-2)" "unprognostic (1.19e-2)" "unprognostic (8.02e-3)" "unprognostic (1.15e-2)" "unprognostic (1.13e-2)" "unprognostic (7.44e-2)" "unprognostic (1.25e-1)" "unprognostic (5.60e-3)" "unprognostic (1.91e-1)" "unprognostic (1.25e-2)" "potential prognostic favorable (5.86e-6)" "unprognostic (3.35e-2)" "unprognostic (1.76e-1)" "unprognostic (2.36e-3)" "unprognostic (2.09e-3)" "unprognostic (6.10e-2)" "unprognostic (4.58e-2)" "unprognostic (2.70e-1)" "unprognostic (3.79e-2)" "unprognostic (6.51e-3)" "unprognostic (3.76e-2)" "unprognostic (7.42e-2)" "unprognostic (3.38e-2)" "unprognostic (1.59e-1)" "unprognostic (1.28e-2)" "unprognostic (2.41e-1)" "unprognostic (1.78e-1)" "unprognostic (6.95e-3)" "unprognostic (2.16e-1)" "unprognostic (4.21e-1)" "unprognostic (2.49e-1)" RPS6KA4 "MSK2, RSK-B" ENSG00000162302 "Ribosomal protein S6 kinase A4" O75676 11 64359148-64372215 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Inflammatory response, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 54.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 48.5;Cytotrophoblasts: 85.6;Migrating cytotrophoblasts: 87.7;pDCs: 133.1;Syncytiotrophoblasts: 48.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 10.5" "Group enriched" "Detected in many" 5 "dendritic cells: 10.5;monocytes: 2.7" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008649, HPA023225" Approved Supported Nucleoplasm,Cytosol No No "Cluster 10: Non-specific - Membrane trafficking" "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 37 Nucleoplasm Cytosol "CAB008649: , HPA023225: " "unprognostic (2.31e-2)" "unprognostic (2.84e-1)" "potential prognostic favorable (2.41e-5)" "unprognostic (3.07e-2)" "unprognostic (1.88e-1)" "unprognostic (9.29e-3)" "unprognostic (2.61e-1)" "unprognostic (6.32e-2)" "unprognostic (3.62e-2)" "unprognostic (7.78e-2)" "unprognostic (3.47e-2)" "unprognostic (5.15e-3)" "unprognostic (8.26e-2)" "potential prognostic unfavorable (7.75e-5)" "unprognostic (4.87e-1)" "unprognostic (1.65e-3)" "unprognostic (5.68e-3)" "unprognostic (4.18e-2)" "unprognostic (4.73e-2)" "unprognostic (2.52e-2)" "unprognostic (3.41e-1)" "unprognostic (2.60e-2)" "unprognostic (2.01e-1)" "unprognostic (5.77e-3)" "unprognostic (2.23e-1)" "unprognostic (7.31e-2)" "unprognostic (2.83e-1)" "unprognostic (1.87e-2)" "unprognostic (1.80e-1)" "unprognostic (9.72e-2)" "unprognostic (2.33e-1)" RPS6KA5 "MSK1, RLPK" ENSG00000100784 "Ribosomal protein S6 kinase A5" O75582 14 90847861-91060641 "Enzymes, Predicted intracellular proteins" "Inflammatory response, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 589.5;Endometrial glandular cells: 1406.0;Mast cells: 638.0;Syncytiotrophoblasts: 632.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001274, HPA001780, CAB025458" Approved Supported Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 15: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 51: Secretory epithelial cells - Mixed function" 25 Nucleoplasm "CAB025458: , HPA001274: , HPA001780: " "unprognostic (1.23e-1)" "unprognostic (2.32e-1)" "unprognostic (8.33e-2)" "unprognostic (1.82e-1)" "unprognostic (2.66e-2)" "unprognostic (2.02e-2)" "unprognostic (9.46e-2)" "unprognostic (2.23e-2)" "potential prognostic favorable (4.38e-4)" "validated prognostic favorable (1.06e-4)" "validated prognostic favorable (2.93e-5)" "unprognostic (1.86e-1)" "unprognostic (1.51e-2)" "unprognostic (1.67e-1)" "unprognostic (7.06e-2)" "unprognostic (1.47e-1)" "unprognostic (2.34e-2)" "unprognostic (1.64e-1)" "unprognostic (1.26e-1)" "unprognostic (6.91e-2)" "unprognostic (2.69e-3)" "unprognostic (4.02e-2)" "unprognostic (4.15e-2)" "unprognostic (4.84e-3)" "unprognostic (3.24e-1)" "unprognostic (1.36e-1)" RPS6KA6 RSK4 ENSG00000072133 "Ribosomal protein S6 kinase A6" Q9UK32 X 84058346-84206356 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 117.1;Corticotrophs: 139.6;Distal convoluted tubule cells: 116.8;Gonadotrophs: 248.8;Lactotrophs: 135.7;Pituitary stem cells: 109.1;Renal connecting tubule cells: 123.5;Somatotrophs: 117.8;Thyrotrophs: 179.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 7.7;prostate cancer: 7.2" "Adipose subcutaneous - Smooth muscle cells, Prostate - Prostate glandular cells, Skeletal muscle - Fibroblasts, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002852, HPA003904" Uncertain Supported Nucleoplasm,Nucleoli,Mitochondria NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 1: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 8 "Nucleoplasm, Mitochondria" Nucleoli "HPA002852: , HPA003904: " "unprognostic (3.31e-2)" "unprognostic (1.47e-1)" "unprognostic (2.30e-3)" "unprognostic (3.27e-2)" "unprognostic (3.35e-2)" "unprognostic (1.01e-3)" "unprognostic (1.72e-2)" "unprognostic (1.71e-1)" "unprognostic (9.31e-2)" "unprognostic (2.72e-1)" "unprognostic (6.73e-2)" "unprognostic (6.26e-2)" "unprognostic (5.25e-2)" "unprognostic (3.02e-3)" "unprognostic (9.66e-2)" "unprognostic (3.52e-1)" "unprognostic (1.78e-2)" "unprognostic (5.39e-2)" "unprognostic (2.39e-1)" "unprognostic (1.97e-2)" "unprognostic (2.16e-2)" "unprognostic (4.08e-3)" RPS6KB1 "p70(S6K)-alpha, PS6K, S6K, S6K1, STK14A" ENSG00000108443 "Ribosomal protein S6 kinase B1" P23443 17 59893046-59950574 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, Translation regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 149.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003838, CAB018346, HPA039442" Approved Supported Nucleoplasm NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Breast cancer - Unknown function" "Cluster 51: Secretory epithelial cells - Mixed function" 29 Nucleoplasm "CAB003838: , CAB018346: , HPA039442: " "unprognostic (3.02e-1)" "unprognostic (7.26e-2)" "unprognostic (1.30e-1)" "unprognostic (4.15e-2)" "unprognostic (2.43e-2)" "unprognostic (1.16e-1)" "unprognostic (2.57e-1)" "unprognostic (1.20e-2)" "unprognostic (3.90e-2)" "potential prognostic unfavorable (1.17e-4)" "unprognostic (3.21e-2)" "unprognostic (9.62e-3)" "unprognostic (5.93e-2)" "unprognostic (9.73e-3)" "unprognostic (2.13e-3)" "unprognostic (2.29e-2)" "potential prognostic unfavorable (3.95e-4)" "unprognostic (2.42e-1)" "unprognostic (3.93e-2)" "unprognostic (1.31e-1)" "unprognostic (1.92e-1)" "unprognostic (2.11e-2)" "unprognostic (1.29e-2)" "unprognostic (1.42e-2)" "unprognostic (1.62e-2)" "unprognostic (2.98e-3)" "unprognostic (4.34e-2)" "unprognostic (2.84e-1)" "unprognostic (1.62e-1)" "unprognostic (1.24e-1)" "unprognostic (6.34e-2)" RPS6KB2 "KLS, P70-BETA, p70S6Kb, S6KB, S6Kbeta, STK14B" ENSG00000175634 "Ribosomal protein S6 kinase B2" Q9UBS0 11 67428460-67435401 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 358.4;Esophageal basal cells: 161.3;Esophageal suprabasal cells: 322.5;Suprabasal keratinocytes: 153.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010010, CAB019404" Approved Supported Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 24: Non-specific - Unknown function" "Cluster 85: Squamous epithelial cells - Keratinization" 30 Cytosol "CAB019404: , HPA010010: " "unprognostic (9.17e-2)" "unprognostic (3.89e-2)" "unprognostic (1.60e-1)" "unprognostic (3.59e-2)" "unprognostic (5.44e-2)" "unprognostic (7.84e-2)" "unprognostic (5.75e-2)" "unprognostic (9.16e-3)" "unprognostic (1.94e-1)" "potential prognostic unfavorable (2.87e-4)" "unprognostic (1.40e-2)" "unprognostic (2.16e-2)" "unprognostic (2.82e-2)" "unprognostic (5.87e-3)" "unprognostic (2.75e-2)" "unprognostic (2.13e-1)" "unprognostic (3.42e-3)" "unprognostic (2.01e-1)" "unprognostic (1.50e-1)" "unprognostic (6.02e-2)" "unprognostic (3.41e-2)" "unprognostic (2.19e-1)" "unprognostic (3.76e-3)" "unprognostic (2.24e-2)" "unprognostic (2.00e-1)" "unprognostic (2.88e-2)" "unprognostic (1.66e-1)" "unprognostic (1.03e-2)" "unprognostic (3.65e-1)" "unprognostic (1.72e-1)" "unprognostic (3.88e-1)" RPS6KC1 "humS6PKh1, RSKL1" ENSG00000136643 "Ribosomal protein S6 kinase C1" Q96S38 1 213051233-213274774 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Prostatic glandular cells: 477.2;Sertoli cells: 628.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 16.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026531, HPA031565" Approved Supported Endosomes,Lysosomes NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 53: Neurons - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 3 "Endosomes, Lysosomes" "HPA026531: , HPA031565: " "unprognostic (2.08e-2)" "unprognostic (8.18e-3)" "unprognostic (2.15e-1)" "unprognostic (8.08e-2)" "unprognostic (6.98e-3)" "unprognostic (1.22e-2)" "unprognostic (1.21e-1)" "unprognostic (2.64e-3)" "unprognostic (5.19e-2)" "unprognostic (1.00e-2)" "potential prognostic favorable (2.53e-4)" "unprognostic (5.07e-2)" "unprognostic (4.75e-2)" "unprognostic (3.16e-2)" "unprognostic (1.99e-1)" "unprognostic (9.35e-2)" "unprognostic (1.37e-1)" "unprognostic (9.71e-2)" "unprognostic (8.00e-2)" "unprognostic (1.38e-2)" "potential prognostic unfavorable (4.99e-4)" "unprognostic (7.78e-2)" "unprognostic (4.12e-3)" "unprognostic (2.02e-1)" "unprognostic (1.59e-2)" "unprognostic (1.24e-1)" "unprognostic (5.26e-2)" "unprognostic (1.14e-1)" "unprognostic (9.63e-2)" "unprognostic (1.24e-3)" "unprognostic (1.55e-1)" RPS6KL1 "MGC11287, RSKL2" ENSG00000198208 "Ribosomal protein S6 kinase like 1" Q9Y6S9 14 74903951-74923302 "Enzymes, Predicted intracellular proteins" "Kinase, Ribonucleoprotein, Ribosomal protein, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 31.0" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 32.9;Cone photoreceptor cells: 58.0;Early primary spermatocytes: 34.6;Myonuclei: 31.5;Retinal amacrine cells: 55.9;Retinal bipolar cells: 84.0;Retinal ganglion cells: 54.1;Retinal horizontal cells: 42.1;Rod photoreceptor cells: 66.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 2.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027451, HPA027794, HPA074903" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 27: Cerebellum - Synaptic function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 2 Nucleoplasm Cytosol "HPA027451: , HPA027794: , HPA074903: " "unprognostic (3.03e-2)" "unprognostic (9.27e-3)" "unprognostic (3.66e-1)" "unprognostic (5.66e-2)" "unprognostic (7.68e-2)" "unprognostic (3.80e-2)" "unprognostic (1.65e-2)" "unprognostic (1.70e-3)" "unprognostic (1.24e-1)" "unprognostic (1.50e-1)" "unprognostic (1.40e-3)" "unprognostic (1.31e-1)" "unprognostic (7.19e-3)" "unprognostic (4.90e-2)" "unprognostic (1.09e-1)" "potential prognostic favorable (1.73e-4)" "unprognostic (6.18e-2)" "unprognostic (1.64e-1)" "unprognostic (9.85e-2)" "unprognostic (2.14e-1)" "unprognostic (1.12e-2)" "unprognostic (4.11e-2)" "unprognostic (2.08e-2)" "unprognostic (1.98e-1)" "unprognostic (2.24e-1)" "unprognostic (1.84e-1)" "unprognostic (1.18e-1)" "unprognostic (1.57e-1)" "unprognostic (4.35e-2)" "unprognostic (7.68e-2)" "unprognostic (1.72e-1)" RPS7 "eS7, S7" ENSG00000171863 "Ribosomal protein S7" P62081 2 3575260-3580920 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Diamond-Blackfan anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 5679.8;Esophageal basal cells: 5851.9;Esophageal suprabasal cells: 6347.7;Extravillous trophoblasts: 6732.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056586 Approved Supported "Endoplasmic reticulum,Cytosol" NA Yes 610000 "Cluster 18: Non-specific - Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 157 "Endoplasmic reticulum, Cytosol" "HPA056586: " "unprognostic (1.23e-2)" "unprognostic (5.00e-3)" "unprognostic (2.55e-1)" "unprognostic (1.38e-2)" "unprognostic (2.81e-1)" "unprognostic (1.76e-1)" "unprognostic (1.94e-1)" "unprognostic (1.30e-1)" "unprognostic (3.53e-3)" "unprognostic (2.67e-1)" "unprognostic (9.45e-3)" "unprognostic (3.42e-2)" "unprognostic (7.03e-3)" "validated prognostic unfavorable (1.28e-4)" "validated prognostic unfavorable (1.46e-8)" "unprognostic (8.53e-2)" "potential prognostic unfavorable (9.24e-4)" "unprognostic (1.31e-3)" "unprognostic (1.75e-1)" "unprognostic (2.96e-1)" "unprognostic (2.66e-3)" "unprognostic (1.18e-1)" "unprognostic (1.23e-3)" "unprognostic (4.23e-2)" "potential prognostic favorable (5.78e-4)" "unprognostic (1.77e-1)" "unprognostic (5.30e-3)" "unprognostic (7.95e-2)" "unprognostic (2.38e-1)" "unprognostic (9.23e-2)" "unprognostic (1.88e-1)" RPS8 S8 ENSG00000142937 "Ribosomal protein S8" P62241 1 44775251-44778779 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Decidual stromal cells: 11326.6;Esophageal apical cells: 11169.5;Esophageal suprabasal cells: 11650.3;Ovarian stromal cells: 11343.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029266 Enhanced "Endoplasmic reticulum,Cytosol" NA NA 180000 "Cluster 18: Non-specific - Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 357 "Endoplasmic reticulum, Cytosol" "HPA029266: " "unprognostic (2.06e-2)" "unprognostic (7.42e-3)" "unprognostic (2.26e-2)" "unprognostic (2.45e-2)" "unprognostic (7.08e-2)" "unprognostic (1.89e-1)" "unprognostic (2.01e-2)" "unprognostic (1.04e-1)" "unprognostic (5.63e-2)" "unprognostic (7.94e-2)" "unprognostic (1.66e-2)" "unprognostic (1.39e-1)" "unprognostic (4.00e-3)" "validated prognostic unfavorable (6.46e-7)" "validated prognostic unfavorable (1.42e-6)" "unprognostic (9.34e-2)" "unprognostic (1.46e-2)" "unprognostic (6.68e-2)" "unprognostic (6.36e-2)" "unprognostic (2.36e-2)" "unprognostic (2.60e-1)" "unprognostic (5.78e-3)" "unprognostic (5.27e-1)" "unprognostic (1.41e-1)" "unprognostic (2.04e-1)" "unprognostic (3.56e-1)" "unprognostic (4.60e-2)" "unprognostic (1.29e-2)" "unprognostic (1.39e-1)" "unprognostic (2.50e-1)" "unprognostic (1.68e-1)" RPS9 S9 ENSG00000170889 "Ribosomal protein S9" P46781 19 54200809-54249003 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast secretory cells: 4912.5;Decidual stromal cells: 4707.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048746 Approved NA Yes 36000 "Cluster 18: Non-specific - Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 132 "HPA048746: " "unprognostic (7.27e-2)" "unprognostic (2.20e-2)" "unprognostic (6.44e-2)" "unprognostic (2.52e-2)" "unprognostic (2.32e-1)" "unprognostic (7.05e-2)" "unprognostic (1.47e-1)" "unprognostic (2.82e-1)" "unprognostic (2.39e-1)" "unprognostic (8.41e-2)" "unprognostic (3.65e-2)" "unprognostic (1.02e-1)" "unprognostic (4.80e-2)" "unprognostic (2.03e-3)" "potential prognostic unfavorable (1.22e-7)" "unprognostic (2.61e-1)" "unprognostic (1.26e-1)" "unprognostic (1.12e-1)" "unprognostic (9.01e-2)" "unprognostic (1.22e-1)" "unprognostic (1.53e-1)" "unprognostic (3.27e-2)" "unprognostic (1.52e-1)" "unprognostic (3.03e-2)" "unprognostic (3.08e-1)" "unprognostic (1.76e-2)" "unprognostic (2.48e-1)" "unprognostic (1.13e-1)" "unprognostic (2.26e-1)" "unprognostic (1.06e-3)" "unprognostic (1.16e-1)" RPSA "37LRP, LAMR1, LRP, p40, SA" ENSG00000168028 "Ribosomal protein SA" P08865 3 39406716-39426255 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Host-virus interaction" "Host cell receptor for virus entry, Receptor, Ribonucleoprotein, Ribosomal protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal basal cells: 4756.0;Esophageal suprabasal cells: 4637.5;Extravillous trophoblasts: 4805.1;Migrating cytotrophoblasts: 4135.2" "Cell type enhanced" "Detected in all" "leukocyte: 437.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" CAB009561 Approved Supported "Plasma membrane,Cytosol" NA NA 750000 "Cluster 24: Non-specific - Transcription" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 257 "Plasma membrane, Cytosol" "CAB009561: " "unprognostic (6.18e-3)" "unprognostic (1.47e-2)" "unprognostic (1.56e-1)" "potential prognostic favorable (3.57e-4)" "unprognostic (1.38e-1)" "unprognostic (2.03e-1)" "unprognostic (1.89e-1)" "potential prognostic favorable (1.46e-4)" "unprognostic (8.15e-2)" "unprognostic (6.55e-2)" "unprognostic (5.16e-3)" "unprognostic (2.38e-3)" "unprognostic (2.41e-1)" "unprognostic (1.12e-3)" "potential prognostic unfavorable (2.27e-10)" "unprognostic (4.93e-2)" "unprognostic (2.93e-2)" "unprognostic (4.94e-2)" "unprognostic (6.36e-2)" "unprognostic (4.97e-2)" "unprognostic (1.02e-1)" "unprognostic (2.09e-3)" "unprognostic (2.43e-1)" "unprognostic (4.30e-2)" "unprognostic (1.70e-2)" "unprognostic (4.20e-2)" "unprognostic (2.91e-2)" "unprognostic (1.74e-1)" "unprognostic (3.78e-1)" "unprognostic (1.41e-1)" "unprognostic (1.45e-1)" RPSAP58 ENSG00000288920 "Ribosomal protein SA pseudogene 58" 19 23762944-23871162 "Cancer-related genes, Predicted intracellular proteins, Ribosomal proteins" "Cancer-related genes" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 189.8;Esophageal suprabasal cells: 107.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 55: Non-specific - Transcription" "Cluster 25: Non-specific - Ribosome" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" RPTN FLJ39117 ENSG00000215853 Repetin Q6XPR3 1 152153595-152159228 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 48.9;skin 1: 28.1" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Head and Neck Squamous Cell Carcinoma (TCGA): 8.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 2.8;colorectal cancer: 1.3;head and neck cancer: 1.3" "Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA030483, HPA030485" Enhanced "Secreted to extracellular matrix" "No annotated function" NA NA "Cluster 58: Skin - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" "HPA030483: , HPA030485: " "unprognostic (1.10e-2)" "unprognostic (7.23e-2)" "unprognostic (1.15e-2)" "unprognostic (3.74e-2)" "unprognostic (2.81e-2)" "unprognostic (8.47e-1)" RPTOR "KIAA1303, KOG1, Mip1, raptor" ENSG00000141564 "Regulatory associated protein of MTOR complex 1" Q8N122 17 80544819-80966371 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Thymic myoid cells: 345.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Smooth muscle cells, Skin - Keratinocyte (granular), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013514, HPA064306" Approved Supported Vesicles,Lysosomes,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 7: Non-specific - Transcription" 102 "Vesicles, Lysosomes" Cytosol "CAB013514: , HPA064306: " "unprognostic (1.70e-1)" "unprognostic (1.88e-1)" "unprognostic (1.44e-2)" "unprognostic (5.93e-2)" "unprognostic (4.48e-1)" "unprognostic (4.78e-2)" "unprognostic (1.80e-1)" "unprognostic (3.19e-1)" "unprognostic (5.76e-2)" "unprognostic (8.11e-2)" "potential prognostic favorable (1.68e-4)" "unprognostic (3.08e-2)" "unprognostic (3.03e-1)" "unprognostic (1.29e-1)" "potential prognostic unfavorable (5.60e-4)" "unprognostic (2.81e-2)" "unprognostic (6.27e-3)" "unprognostic (4.07e-3)" "unprognostic (2.72e-2)" "unprognostic (2.57e-2)" "unprognostic (3.64e-2)" "unprognostic (1.44e-1)" "unprognostic (4.46e-2)" "unprognostic (9.13e-2)" "unprognostic (1.81e-2)" "unprognostic (3.46e-3)" "unprognostic (2.26e-1)" "unprognostic (1.31e-1)" "unprognostic (3.53e-1)" "unprognostic (2.03e-3)" "unprognostic (1.72e-1)" RPUSD1 "C16orf40, MGC19600, RLUCL" ENSG00000007376 "RNA pseudouridine synthase domain containing 1" Q9UJJ7 16 784974-788397 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 35.8;Migrating cytotrophoblasts: 30.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041144, HPA041938" Approved Approved "Nucleoplasm,Golgi apparatus,Cell Junctions,Cytosol" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 1 "Golgi apparatus" "Nucleoplasm, Cell Junctions, Cytosol" "HPA041144: , HPA041938: " "unprognostic (2.43e-1)" "unprognostic (2.86e-1)" "unprognostic (1.15e-1)" "unprognostic (5.65e-3)" "unprognostic (2.98e-2)" "unprognostic (1.24e-1)" "unprognostic (9.87e-2)" "unprognostic (1.01e-1)" "unprognostic (3.02e-2)" "unprognostic (4.95e-2)" "unprognostic (8.33e-2)" "unprognostic (1.21e-3)" "unprognostic (8.40e-2)" "validated prognostic unfavorable (9.41e-6)" "validated prognostic unfavorable (6.45e-4)" "unprognostic (9.99e-3)" "unprognostic (4.68e-2)" "unprognostic (1.21e-1)" "unprognostic (5.49e-2)" "unprognostic (2.11e-1)" "unprognostic (2.04e-1)" "unprognostic (1.89e-1)" "unprognostic (3.46e-1)" "unprognostic (1.06e-1)" "unprognostic (1.09e-2)" "unprognostic (1.54e-2)" "unprognostic (3.69e-2)" "unprognostic (1.93e-2)" "unprognostic (2.11e-1)" "unprognostic (1.42e-2)" "unprognostic (2.51e-1)" RPUSD2 "C15orf19, C18B11, FLJ31409, PUS9" ENSG00000166133 "RNA pseudouridine synthase domain containing 2" Q8IZ73 15 40569299-40574949 "Predicted intracellular proteins" "mRNA processing" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042079, HPA042194" Approved Approved Nucleoplasm,Microtubules NA NA "Cluster 24: Non-specific - Transcription" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" "Nucleoplasm, Microtubules" "HPA042079: , HPA042194: " "unprognostic (9.75e-2)" "unprognostic (7.54e-2)" "unprognostic (6.92e-2)" "unprognostic (1.10e-1)" "unprognostic (4.83e-3)" "unprognostic (2.25e-1)" "unprognostic (1.73e-2)" "unprognostic (9.61e-2)" "unprognostic (3.93e-2)" "unprognostic (6.34e-2)" "potential prognostic favorable (1.81e-4)" "unprognostic (1.75e-2)" "potential prognostic favorable (6.49e-4)" "unprognostic (3.67e-1)" "unprognostic (3.29e-3)" "unprognostic (1.65e-1)" "unprognostic (5.36e-2)" "unprognostic (9.16e-2)" "unprognostic (9.17e-3)" "unprognostic (1.92e-1)" "unprognostic (1.09e-1)" "unprognostic (4.61e-3)" "unprognostic (2.17e-1)" "unprognostic (3.18e-2)" "unprognostic (1.04e-2)" "unprognostic (2.13e-1)" "unprognostic (4.86e-2)" "unprognostic (2.82e-1)" "unprognostic (1.14e-1)" "unprognostic (1.50e-1)" "unprognostic (4.24e-2)" RPUSD3 MGC29784 ENSG00000156990 "RNA pseudouridine synthase D3" Q6P087 3 9837849-9844602 "Predicted intracellular proteins" "mRNA processing" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 80.2;Late primary spermatocytes: 177.1;Megakaryocytes: 80.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037551, HPA037552" Uncertain Approved Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 10 Nucleoplasm "HPA037551: , HPA037552: " "unprognostic (5.07e-2)" "unprognostic (2.86e-2)" "unprognostic (6.71e-2)" "unprognostic (1.14e-1)" "unprognostic (2.76e-1)" "unprognostic (4.05e-2)" "unprognostic (3.00e-2)" "unprognostic (3.78e-3)" "unprognostic (3.32e-2)" "potential prognostic unfavorable (5.09e-6)" "unprognostic (2.86e-1)" "unprognostic (1.07e-1)" "unprognostic (1.89e-3)" "validated prognostic unfavorable (2.28e-5)" "validated prognostic unfavorable (7.15e-5)" "unprognostic (7.65e-3)" "unprognostic (3.06e-2)" "unprognostic (6.18e-2)" "unprognostic (1.91e-1)" "unprognostic (8.99e-2)" "unprognostic (7.45e-3)" "unprognostic (1.34e-1)" "unprognostic (9.22e-2)" "unprognostic (1.81e-1)" "unprognostic (3.04e-1)" "unprognostic (1.54e-1)" "unprognostic (3.92e-2)" "unprognostic (1.61e-1)" "unprognostic (1.44e-1)" "unprognostic (4.49e-2)" "unprognostic (2.75e-1)" RPUSD4 FLJ14494 ENSG00000165526 "RNA pseudouridine synthase D4" Q96CM3 11 126202096-126211692 "Metabolic proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, rRNA processing, tRNA processing" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 126.8;tongue: 70.1" "Cell type enhanced" "Detected in many" "Myonuclei: 55.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039689 Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 21: Non-specific - Metabolism" "Cluster 24: Non-specific - Unknown function" "Cluster 15: Non-specific - Protein processing" 53 Mitochondria Nucleoplasm "HPA039689: " "unprognostic (1.30e-1)" "unprognostic (1.91e-2)" "unprognostic (2.63e-2)" "unprognostic (1.70e-1)" "unprognostic (1.19e-1)" "unprognostic (1.07e-2)" "unprognostic (4.07e-2)" "potential prognostic favorable (2.13e-4)" "unprognostic (2.88e-2)" "unprognostic (2.20e-1)" "potential prognostic favorable (1.66e-6)" "unprognostic (1.06e-3)" "unprognostic (1.03e-1)" "validated prognostic unfavorable (7.75e-6)" "validated prognostic unfavorable (3.31e-5)" "unprognostic (2.56e-2)" "potential prognostic unfavorable (4.64e-6)" "unprognostic (6.81e-2)" "unprognostic (2.10e-1)" "unprognostic (2.63e-2)" "unprognostic (3.30e-1)" "unprognostic (5.04e-3)" "unprognostic (3.88e-2)" "unprognostic (1.23e-2)" "unprognostic (1.89e-2)" "unprognostic (3.33e-2)" "unprognostic (2.37e-3)" "unprognostic (1.71e-1)" "unprognostic (3.17e-1)" "unprognostic (2.40e-1)" "unprognostic (3.36e-2)" RRAD "RAD, REM3" ENSG00000166592 "RRAD, Ras related glycolysis inhibitor and calcium channel regulator" P55042 16 66921679-66925536 "Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "heart muscle: 316.2;skeletal muscle: 776.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 225.4;Endometrial ciliated cells: 512.0;Endometrial luminal cells: 480.4;Endometrial secretory cells: 327.0;Epididymal efferent duct ciliated cells: 391.2;Esophageal apical cells: 351.9;Esophageal suprabasal cells: 404.2;Fallopian tube ciliated cells: 549.4;Pericytes: 228.9;Plasma cells: 258.9;Respiratory ciliated cells: 557.3;Thymic myoid cells: 584.6;Vascular smooth muscle cells: 437.5" "Group enriched" "Detected in many" 6 "astrocyte: 21.6;choroid plexus epithelial cell: 24.7;pericyte: 66.8;vascular associated smooth muscle cell: 83.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Kidney cancer: 137.9" "Adipose subcutaneous - Smooth muscle cells, Stomach - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA041755 Uncertain Approved "Nucleoplasm,Golgi apparatus,Plasma membrane,Flagellar centriole" NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 78: Plasma cells - Antibody production & ER-stress response" 8 "Plasma membrane" "Nucleoplasm, Golgi apparatus, Flagellar centriole" "HPA041755: " "unprognostic (5.92e-2)" "unprognostic (4.17e-2)" "unprognostic (4.38e-2)" "unprognostic (1.24e-1)" "unprognostic (3.91e-1)" "unprognostic (1.47e-1)" "unprognostic (7.24e-3)" "unprognostic (1.34e-1)" "unprognostic (1.08e-1)" "unprognostic (1.24e-1)" "unprognostic (1.04e-2)" "unprognostic (8.58e-2)" "unprognostic (1.68e-1)" "unprognostic (3.74e-2)" "unprognostic (4.90e-3)" "unprognostic (2.63e-2)" "unprognostic (9.79e-2)" "unprognostic (4.52e-3)" "unprognostic (1.52e-1)" "unprognostic (5.82e-3)" "unprognostic (1.70e-2)" "unprognostic (1.81e-2)" "unprognostic (3.00e-2)" "unprognostic (7.71e-2)" "unprognostic (1.94e-2)" "unprognostic (2.13e-2)" "unprognostic (1.07e-1)" "unprognostic (6.82e-3)" "unprognostic (9.99e-2)" "unprognostic (5.73e-2)" "unprognostic (7.49e-2)" RRAGA "FIP-1, RAGA" ENSG00000155876 "Ras related GTP binding A" Q7L523 9 19049427-19051025 "Essential proteins, Predicted intracellular proteins" "Apoptosis, Host-virus interaction" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Decidual stromal cells: 221.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003734 Supported Approved "Golgi apparatus,Vesicles" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 97: Non-specific - Cellular respiration" 35 "Golgi apparatus, Vesicles" "HPA003734: " "unprognostic (1.55e-1)" "unprognostic (2.07e-1)" "unprognostic (2.07e-1)" "unprognostic (4.36e-2)" "unprognostic (2.41e-2)" "unprognostic (2.42e-1)" "unprognostic (9.30e-2)" "unprognostic (5.29e-2)" "potential prognostic unfavorable (9.61e-4)" "unprognostic (2.80e-1)" "potential prognostic favorable (4.63e-5)" "unprognostic (6.77e-2)" "unprognostic (2.96e-2)" "unprognostic (1.15e-2)" "unprognostic (8.11e-2)" "unprognostic (7.14e-2)" "unprognostic (2.11e-3)" "unprognostic (1.55e-1)" "unprognostic (3.71e-1)" "unprognostic (4.43e-1)" "unprognostic (1.30e-1)" "unprognostic (1.54e-2)" "unprognostic (1.27e-1)" "unprognostic (2.68e-1)" "unprognostic (9.37e-2)" "unprognostic (1.09e-1)" "unprognostic (1.44e-1)" "unprognostic (3.46e-2)" "unprognostic (1.72e-1)" "unprognostic (3.49e-2)" "unprognostic (1.38e-1)" RRAGB ENSG00000083750 "Ras related GTP binding B" Q5VZM2 X 55717749-55758774 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003734 Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 22: Epididymis - Mixed function" "Cluster 14: Neurons - Synaptic function" "Cluster 36: Non-specific - mRNA processing" "Cluster 7: Non-specific - Transcription" 17 "Golgi apparatus, Vesicles" "HPA003734: " "unprognostic (1.69e-3)" "unprognostic (7.87e-3)" "unprognostic (1.35e-1)" "unprognostic (4.10e-2)" "unprognostic (1.58e-3)" "unprognostic (1.81e-2)" "unprognostic (1.16e-3)" "unprognostic (1.50e-3)" "unprognostic (1.28e-1)" "unprognostic (1.03e-2)" "potential prognostic favorable (1.67e-4)" "unprognostic (2.06e-2)" "unprognostic (1.17e-1)" "unprognostic (2.52e-1)" "unprognostic (5.69e-2)" "unprognostic (9.79e-2)" "unprognostic (1.32e-1)" "unprognostic (6.85e-3)" "unprognostic (3.32e-2)" "unprognostic (2.69e-1)" "unprognostic (2.59e-1)" "unprognostic (1.17e-1)" "unprognostic (8.60e-3)" "unprognostic (3.49e-2)" "unprognostic (4.10e-2)" "unprognostic (1.01e-2)" "unprognostic (2.43e-2)" "unprognostic (5.47e-2)" "unprognostic (1.21e-1)" "unprognostic (1.90e-1)" "unprognostic (9.16e-2)" RRAGC "FLJ13311, GTR2" ENSG00000116954 "Ras related GTP binding C" Q9HB90 1 38838198-38859772 "Disease related genes, Predicted intracellular proteins" Hydrolase "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 65.3;Syncytiotrophoblasts: 107.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018247, HPA055489" Supported Supported Nucleoplasm,Vesicles NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 27: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 34 "Nucleoplasm, Vesicles" "HPA018247: , HPA055489: " "unprognostic (2.76e-2)" "unprognostic (3.14e-1)" "unprognostic (1.14e-1)" "unprognostic (4.49e-2)" "unprognostic (3.13e-1)" "unprognostic (7.67e-3)" "unprognostic (1.96e-1)" "unprognostic (5.98e-2)" "unprognostic (3.78e-2)" "unprognostic (2.01e-2)" "potential prognostic favorable (1.14e-8)" "unprognostic (1.03e-2)" "unprognostic (1.92e-2)" "potential prognostic unfavorable (3.08e-9)" "unprognostic (2.37e-3)" "unprognostic (3.29e-1)" "unprognostic (6.85e-2)" "unprognostic (4.94e-2)" "unprognostic (7.67e-2)" "unprognostic (6.09e-2)" "unprognostic (1.33e-3)" "unprognostic (2.01e-2)" "unprognostic (6.07e-2)" "unprognostic (1.66e-1)" "unprognostic (1.34e-1)" "unprognostic (3.65e-1)" "unprognostic (6.85e-2)" "unprognostic (8.86e-2)" "unprognostic (8.98e-2)" "unprognostic (1.26e-1)" "unprognostic (1.87e-1)" RRAGD "bA11D8.2.1, DKFZP761H171" ENSG00000025039 "Ras related GTP binding D" Q9NQL2 6 89364616-89412273 "Human disease related genes, Predicted intracellular proteins" Hydrolase "Cardiomyopathy, Disease variant, Primary hypomagnesemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 79.1;tongue: 56.3" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 140.8;Esophageal apical cells: 208.6;Esophageal suprabasal cells: 178.4;Myonuclei: 144.0;Neutrophil progenitors: 165.2;Neutrophils: 164.7;Salivary acinar cells: 250.4;Salivary duct cells: 253.7" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 53.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 3.3" "Group enriched" "Detected in many" 7 "granulocytes: 3.3;monocytes: 2.4" "Cancer enhanced" "Detected in many" "Myeloma: 28.0" "Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068664 Approved Approved Nucleoplasm,Vesicles,Centrosome NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 31: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 23 Nucleoplasm "Vesicles, Centrosome" "HPA068664: " "unprognostic (5.37e-2)" "unprognostic (3.43e-2)" "unprognostic (1.61e-1)" "unprognostic (8.11e-2)" "unprognostic (8.62e-3)" "unprognostic (5.65e-2)" "unprognostic (1.68e-1)" "unprognostic (1.45e-1)" "unprognostic (1.90e-1)" "unprognostic (5.16e-3)" "validated prognostic favorable (2.57e-8)" "validated prognostic favorable (5.98e-4)" "unprognostic (6.05e-2)" "unprognostic (1.64e-3)" "potential prognostic unfavorable (2.06e-4)" "unprognostic (8.30e-3)" "unprognostic (6.42e-2)" "unprognostic (5.79e-1)" "unprognostic (2.01e-1)" "unprognostic (4.48e-2)" "unprognostic (1.93e-1)" "unprognostic (3.47e-3)" "unprognostic (1.52e-3)" "unprognostic (1.07e-1)" "unprognostic (1.75e-2)" "unprognostic (1.88e-1)" "unprognostic (2.12e-2)" "potential prognostic unfavorable (5.84e-4)" "unprognostic (2.33e-1)" "unprognostic (3.45e-2)" "unprognostic (1.39e-1)" RRAS R-Ras ENSG00000126458 "RAS related" P10301 19 49635292-49640143 "Predicted intracellular proteins, RAS pathway related proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 476.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 164.3;Breast lactating cells: 138.6;Breast myoepithelial cells: 123.1;Decidual stromal cells: 243.1;Hepatic stellate cells: 129.1;Megakaryocytes: 136.0;Pericytes: 144.9;Smooth muscle cells: 218.0;Vascular smooth muscle cells: 275.9" "Group enriched" "Detected in many" 8 "endothelial cell: 74.1;fibroblast: 36.2;pericyte: 120.1;vascular associated smooth muscle cell: 131.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "intermediate monocyte: 20.9;non-classical monocyte: 25.1" "Lineage enriched" "Detected in many" 7 "monocytes: 25.1" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Prostate - Smooth muscle cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010160, HPA060364, CAB069439" Uncertain Approved Vesicles NA NA 150000 "Cluster 40: Monocytes - Innate immune response" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 47: Endothelial cells - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 7 Vesicles "CAB010160: , CAB069439: , HPA060364: " "unprognostic (2.36e-2)" "unprognostic (2.82e-2)" "unprognostic (1.60e-1)" "unprognostic (1.59e-2)" "unprognostic (2.93e-1)" "unprognostic (2.15e-1)" "potential prognostic unfavorable (4.85e-4)" "unprognostic (1.61e-3)" "unprognostic (6.56e-2)" "unprognostic (1.15e-1)" "potential prognostic unfavorable (1.11e-6)" "unprognostic (1.86e-2)" "unprognostic (2.14e-3)" "unprognostic (5.26e-3)" "unprognostic (2.18e-2)" "potential prognostic unfavorable (8.67e-4)" "unprognostic (3.45e-1)" "unprognostic (1.34e-2)" "unprognostic (9.56e-3)" "unprognostic (1.38e-1)" "unprognostic (5.28e-3)" "potential prognostic unfavorable (3.60e-4)" "unprognostic (3.03e-2)" "unprognostic (1.02e-2)" "unprognostic (2.16e-1)" "unprognostic (1.23e-2)" "unprognostic (7.17e-2)" "unprognostic (5.63e-2)" "unprognostic (3.03e-3)" "unprognostic (1.74e-2)" "unprognostic (6.63e-2)" RRAS2 TC21 ENSG00000133818 "RAS related 2" P62070 11 14277922-14364506 "Disease related genes, Human disease related genes, Predicted intracellular proteins, RAS pathway related proteins" Hydrolase "Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epicardial cells: 332.0;Oocytes: 280.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 11.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Spleen - B-cells (Spleen), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010420, HPA050942" Approved NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 29: Forebrain - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 51: Secretory epithelial cells - Mixed function" 14 "CAB010420: , HPA050942: " "unprognostic (2.61e-2)" "unprognostic (9.47e-2)" "potential prognostic favorable (4.32e-4)" "unprognostic (8.63e-3)" "unprognostic (1.72e-1)" "unprognostic (6.36e-3)" "unprognostic (7.25e-2)" "unprognostic (9.20e-2)" "unprognostic (2.83e-3)" "unprognostic (1.94e-1)" "potential prognostic favorable (1.00e-4)" "unprognostic (2.50e-1)" "unprognostic (8.55e-2)" "potential prognostic unfavorable (4.94e-4)" "unprognostic (1.19e-1)" "unprognostic (4.86e-3)" "potential prognostic unfavorable (3.76e-4)" "unprognostic (1.17e-1)" "unprognostic (2.16e-3)" "unprognostic (1.64e-1)" "unprognostic (7.94e-3)" "validated prognostic unfavorable (1.57e-4)" "validated prognostic unfavorable (4.65e-4)" "unprognostic (1.77e-2)" "unprognostic (2.26e-2)" "unprognostic (3.10e-1)" "unprognostic (9.61e-2)" "unprognostic (3.88e-2)" "unprognostic (1.66e-1)" "unprognostic (3.65e-2)" "unprognostic (2.48e-1)" RRBP1 "ES/130, hES, p180" ENSG00000125844 "Ribosome binding protein 1" Q9P2E9 20 17613678-17682295 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 469.5" "Cell type enhanced" "Detected in all" "Pancreatic acinar cells: 695.0;Salivary acinar cells: 700.2;Syncytiotrophoblasts: 721.5" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 133.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 38.6;plasmacytoid DC: 44.4" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Minor Salivary Gland - Minor salivary glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009026, HPA011924" Enhanced Enhanced "Endoplasmic reticulum" NA NA 2200000 "Cluster 29: Non-specific - Unknown function" "Cluster 8: Pancreas - Proteolysis" "Cluster 30: White matter - Myelination" "Cluster 63: Non-specific - Protein processing" "Cluster 65: Non-specific - Cell growth & division" 30 "Endoplasmic reticulum" "HPA009026: , HPA011924: " "unprognostic (1.96e-1)" "potential prognostic unfavorable (6.70e-4)" "unprognostic (4.04e-3)" "potential prognostic unfavorable (6.34e-5)" "unprognostic (7.20e-2)" "unprognostic (5.66e-2)" "unprognostic (6.15e-2)" "potential prognostic unfavorable (3.08e-4)" "unprognostic (1.13e-1)" "unprognostic (9.02e-2)" "unprognostic (5.54e-2)" "potential prognostic unfavorable (5.39e-4)" "unprognostic (2.13e-2)" "unprognostic (5.35e-2)" "unprognostic (3.84e-1)" "unprognostic (2.35e-1)" "unprognostic (2.47e-1)" "unprognostic (4.35e-3)" "unprognostic (4.17e-2)" "unprognostic (3.24e-2)" "unprognostic (1.61e-1)" "unprognostic (2.55e-1)" "unprognostic (1.29e-2)" "unprognostic (2.51e-1)" "unprognostic (3.56e-1)" "unprognostic (1.70e-1)" "unprognostic (3.97e-2)" "unprognostic (4.19e-2)" "unprognostic (3.68e-1)" "unprognostic (1.81e-1)" "unprognostic (3.08e-2)" RREB1 HNT ENSG00000124782 "Ras responsive element binding protein 1" Q92766 6 7107597-7251980 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubule cells: 548.2" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 389.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001756, HPA034843" Approved Supported "Nucleoli fibrillar center,Nuclear speckles" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 28: Non-specific - Nuclear processes" "Cluster 51: Secretory epithelial cells - Mixed function" 16 "Nuclear speckles" "Nucleoli fibrillar center" "HPA001756: , HPA034843: " "unprognostic (1.00e-1)" "unprognostic (4.30e-2)" "unprognostic (1.41e-1)" "unprognostic (4.11e-3)" "unprognostic (1.84e-1)" "unprognostic (3.81e-1)" "unprognostic (1.27e-1)" "unprognostic (8.42e-2)" "unprognostic (2.16e-3)" "unprognostic (5.22e-2)" "potential prognostic favorable (3.79e-6)" "unprognostic (1.41e-2)" "unprognostic (9.43e-3)" "unprognostic (1.21e-1)" "unprognostic (4.21e-2)" "unprognostic (1.87e-1)" "unprognostic (4.34e-2)" "unprognostic (1.89e-2)" "unprognostic (8.05e-3)" "unprognostic (3.43e-2)" "unprognostic (2.66e-1)" "unprognostic (1.13e-2)" "unprognostic (2.41e-2)" "unprognostic (1.67e-1)" "unprognostic (1.95e-2)" "unprognostic (1.38e-1)" "unprognostic (1.34e-2)" "unprognostic (1.63e-1)" "unprognostic (2.93e-1)" "unprognostic (2.10e-2)" "unprognostic (2.77e-1)" RRH peropsin ENSG00000180245 "Retinal pigment epithelium-derived rhodopsin homolog" O14718 4 109827972-109849123 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 87 "retina: 70.0" "Group enriched" "Detected in many" 22 "Müller glia: 233.2;Retinal pigment epithelial cells: 349.6" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" NA NA "Cluster 42: Retina - Visual perception" "Cluster 53: Neurons - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" 1 "unprognostic (4.05e-1)" "unprognostic (1.41e-2)" RRM1 ENSG00000167325 "Ribonucleotide reductase catalytic subunit M1" P23921 11 4094707-4138932 "Enzymes, Essential proteins, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Deoxyribonucleotide synthesis" "Allosteric enzyme, Oxidoreductase" "FDA approved drug targets, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 167.9;Erythrocyte progenitors: 209.6;Monocyte progenitors: 148.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022093, HPA057265, HPA064297" Enhanced Supported "Plasma membrane,Centriolar satellite,Basal body,Cytosol" NA Yes 150000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 15 Cytosol "Plasma membrane, Centriolar satellite, Basal body" "CAB022093: , HPA057265: , HPA064297: " "unprognostic (6.58e-3)" "unprognostic (6.05e-2)" "unprognostic (2.46e-2)" "unprognostic (9.03e-2)" "unprognostic (3.74e-3)" "unprognostic (1.93e-1)" "unprognostic (4.89e-1)" "unprognostic (3.01e-2)" "unprognostic (1.33e-1)" "unprognostic (1.42e-1)" "potential prognostic favorable (1.26e-7)" "unprognostic (3.41e-1)" "unprognostic (1.83e-1)" "unprognostic (1.33e-2)" "potential prognostic unfavorable (2.18e-4)" "unprognostic (8.65e-3)" "potential prognostic unfavorable (4.80e-6)" "unprognostic (1.68e-1)" "unprognostic (1.34e-1)" "unprognostic (3.67e-1)" "unprognostic (1.60e-1)" "potential prognostic unfavorable (4.50e-5)" "unprognostic (1.95e-1)" "unprognostic (5.11e-2)" "unprognostic (4.07e-3)" "unprognostic (1.16e-1)" "unprognostic (4.26e-2)" "unprognostic (7.69e-2)" "unprognostic (2.12e-1)" "unprognostic (4.94e-2)" "unprognostic (1.76e-2)" RRM2 "C2orf48, FLJ25102" ENSG00000171848 "Ribonucleotide reductase regulatory subunit M2" P31350 2 10120698-10211725 "Enzymes, Essential proteins, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Deoxyribonucleotide synthesis" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 41.5;lymphoid tissue: 54.1" "Cell type enhanced" "Detected in many" "Enteric transient amplifying cells: 146.4;Erythrocyte progenitors: 193.2;Esophageal basal cells: 170.2;Extravillous trophoblasts: 335.6;Gastric progenitor cells: 139.7;Megakaryocyte progenitors: 121.7;Migrating cytotrophoblasts: 131.4;Monocyte progenitors: 409.0;Neutrophil progenitors: 279.3;Paneth cells: 92.8;Plasma cells: 117.5" "Cell type enhanced" "Detected in many" "leukocyte: 13.3;upper-layer intratelencephalic: 6.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA056994 Enhanced Supported Nucleoplasm,Cytosol Yes Yes 14000 "Cluster 15: NK-cells - Unknown function" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 48: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Non-specific - Cell proliferation" 23 Cytosol Nucleoplasm "HPA056994: " "unprognostic (3.20e-1)" "unprognostic (5.87e-2)" "unprognostic (3.48e-1)" "unprognostic (2.04e-1)" "unprognostic (3.29e-1)" "unprognostic (8.64e-2)" "unprognostic (1.91e-1)" "unprognostic (7.09e-2)" "unprognostic (2.28e-1)" "potential prognostic unfavorable (1.93e-4)" "validated prognostic unfavorable (2.93e-7)" "validated prognostic unfavorable (1.59e-7)" "potential prognostic unfavorable (1.54e-11)" "validated prognostic unfavorable (4.94e-7)" "validated prognostic unfavorable (1.47e-8)" "potential prognostic unfavorable (8.75e-8)" "unprognostic (7.78e-3)" "unprognostic (5.95e-3)" "unprognostic (1.03e-1)" "unprognostic (3.07e-2)" "unprognostic (8.91e-2)" "potential prognostic unfavorable (3.66e-5)" "unprognostic (9.28e-3)" "unprognostic (8.90e-2)" "unprognostic (1.39e-2)" "unprognostic (1.73e-2)" "unprognostic (3.35e-3)" "unprognostic (1.30e-2)" "unprognostic (4.74e-1)" "unprognostic (6.25e-2)" "unprognostic (2.07e-1)" RRM2B p53R2 ENSG00000048392 "Ribonucleotide reductase regulatory TP53 inducible subunit M2B" Q7LG56 8 102204502-102238961 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Deoxyribonucleotide synthesis, DNA damage, DNA repair" Oxidoreductase "Deafness, Disease variant, FDA approved drug targets, Neuropathy, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 141.7;Thymic myoid cells: 186.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006854, HPA028812" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 8 Nucleoplasm Cytosol "CAB006854: , HPA028812: " "potential prognostic favorable (7.15e-4)" "unprognostic (1.08e-3)" "unprognostic (8.69e-3)" "unprognostic (1.46e-3)" "unprognostic (3.92e-2)" "unprognostic (6.02e-2)" "unprognostic (3.33e-2)" "potential prognostic unfavorable (1.71e-4)" "unprognostic (7.61e-2)" "unprognostic (1.36e-3)" "validated prognostic favorable (2.67e-7)" "validated prognostic favorable (6.06e-4)" "unprognostic (1.47e-1)" "unprognostic (8.63e-2)" "unprognostic (3.30e-2)" "unprognostic (2.94e-3)" "unprognostic (1.93e-1)" "unprognostic (2.03e-2)" "unprognostic (8.19e-2)" "unprognostic (1.02e-2)" "potential prognostic unfavorable (3.33e-6)" "unprognostic (3.50e-2)" "unprognostic (2.84e-3)" "unprognostic (8.56e-2)" "unprognostic (2.75e-1)" "unprognostic (6.21e-2)" "unprognostic (1.93e-1)" "unprognostic (3.06e-1)" "unprognostic (1.63e-1)" "unprognostic (3.02e-1)" "unprognostic (2.83e-1)" RRN3 "DKFZp566E104, TIF-IA" ENSG00000085721 "RRN3 homolog, RNA polymerase I transcription factor" Q9NYV6 16 15060033-15094311 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bergmann glia: 21.0;Brain excitatory neurons: 18.7;Brain inhibitory neurons: 19.8;Distal convoluted tubule cells: 27.4;Loop of henle epithelial cells: 26.2;Oligodendrocyte progenitor cells: 20.0;Papillary tip epithelial cells: 19.1;Podocytes: 26.8;Proximal tubule cells: 29.9;Renal collecting duct intercalated cells: 28.9;Renal collecting duct principal cells: 22.9;Renal connecting tubule cells: 23.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049837 Supported Supported "Nucleoli rim" NA No "Cluster 15: NK-cells - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 49: HMC-1 - Innate immune response" "Cluster 102: Non-specific - Mixed function" 11 "Nucleoli rim" "HPA049837: " "unprognostic (2.57e-1)" "unprognostic (2.08e-3)" "unprognostic (1.00e-1)" "unprognostic (3.43e-1)" "unprognostic (1.06e-1)" "unprognostic (2.62e-2)" "unprognostic (3.09e-1)" "unprognostic (1.29e-2)" "potential prognostic unfavorable (8.69e-4)" "unprognostic (1.03e-1)" "potential prognostic favorable (6.00e-4)" "unprognostic (2.12e-1)" "unprognostic (7.96e-3)" "unprognostic (1.36e-1)" "unprognostic (4.59e-2)" "unprognostic (1.88e-2)" "unprognostic (1.24e-1)" "unprognostic (3.15e-1)" "unprognostic (7.67e-2)" "unprognostic (3.73e-2)" "potential prognostic unfavorable (8.05e-4)" "unprognostic (1.26e-3)" "unprognostic (2.59e-2)" "unprognostic (2.69e-2)" "unprognostic (4.12e-2)" "unprognostic (3.63e-1)" "unprognostic (2.28e-1)" "unprognostic (1.89e-1)" "unprognostic (1.50e-2)" "unprognostic (1.59e-2)" "unprognostic (1.88e-1)" RRP1 "D21S2056E, NNP-1, Nop52, RRP1A" ENSG00000160214 "Ribosomal RNA processing 1" P56182 21 43789513-43805293 "Essential proteins, Predicted intracellular proteins" "rRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 87.0;Esophageal suprabasal cells: 80.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016818, HPA018166" Approved Enhanced "Nucleoli,Mitotic chromosome" Yes No 46000 "Cluster 30: Non-specific - DNA binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 17: Non-specific - RNA processing" 32 "Nucleoli, Mitotic chromosome" "HPA016818: , HPA018166: " "unprognostic (3.13e-2)" "unprognostic (1.28e-1)" "unprognostic (5.37e-2)" "unprognostic (3.34e-1)" "unprognostic (4.79e-2)" "unprognostic (2.48e-1)" "unprognostic (1.95e-1)" "unprognostic (1.29e-3)" "unprognostic (7.86e-2)" "unprognostic (6.90e-2)" "unprognostic (9.28e-2)" "unprognostic (7.60e-2)" "unprognostic (7.11e-2)" "potential prognostic unfavorable (9.45e-5)" "unprognostic (2.98e-3)" "unprognostic (6.80e-2)" "unprognostic (1.42e-3)" "unprognostic (3.41e-2)" "unprognostic (2.12e-1)" "unprognostic (6.32e-2)" "unprognostic (2.64e-1)" "unprognostic (1.42e-1)" "unprognostic (2.18e-1)" "unprognostic (6.41e-3)" "unprognostic (4.53e-2)" "unprognostic (1.01e-2)" "unprognostic (1.14e-1)" "unprognostic (2.93e-1)" "unprognostic (8.23e-2)" "unprognostic (1.21e-1)" "unprognostic (8.09e-2)" RRP12 KIAA0690 ENSG00000052749 "Ribosomal RNA processing 12 homolog" Q5JTH9 10 97356358-97426076 "Essential proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 85.9;skeletal muscle: 36.0" "Cell type enhanced" "Detected in many" "Kupffer cells: 222.4;Monocyte progenitors: 319.4;monocytes: 176.4;Neutrophil progenitors: 288.4;Neutrophils: 284.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 26.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049945, HPA074403" Supported "Nucleoli,Vesicles,Plasma membrane,Cytosol" No No 4300 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 52: Non-specific - Mitochondria" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 43 Nucleoli "Vesicles, Plasma membrane, Cytosol" "HPA049945: , HPA074403: " "unprognostic (2.85e-1)" "unprognostic (4.86e-2)" "unprognostic (5.33e-2)" "unprognostic (2.65e-3)" "unprognostic (1.80e-2)" "unprognostic (8.62e-2)" "unprognostic (2.60e-1)" "unprognostic (1.45e-3)" "unprognostic (6.96e-2)" "unprognostic (1.24e-1)" "unprognostic (5.74e-2)" "unprognostic (6.68e-3)" "unprognostic (2.37e-1)" "potential prognostic unfavorable (8.08e-9)" "unprognostic (1.28e-3)" "unprognostic (7.72e-2)" "unprognostic (1.71e-2)" "unprognostic (3.35e-1)" "unprognostic (1.83e-1)" "unprognostic (5.74e-2)" "unprognostic (2.76e-1)" "unprognostic (1.51e-1)" "unprognostic (1.26e-1)" "unprognostic (7.69e-3)" "unprognostic (3.30e-2)" "unprognostic (1.98e-2)" "unprognostic (8.18e-2)" "unprognostic (2.43e-2)" "unprognostic (4.21e-1)" "unprognostic (1.45e-2)" "unprognostic (8.65e-2)" RRP15 "CGI-115, KIAA0507" ENSG00000067533 "Ribosomal RNA processing 15 homolog" Q9Y3B9 1 218285293-218337983 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024639 Approved Approved "Nucleoplasm,Nucleoli rim,Mitotic chromosome,Mitochondria" Yes No "Cluster 24: Non-specific - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 2: Neurons - Nucleosome" "Cluster 45: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 44 "Nucleoli rim, Mitotic chromosome" "Nucleoplasm, Mitochondria" "HPA024639: " "unprognostic (7.24e-2)" "unprognostic (1.91e-2)" "unprognostic (2.01e-1)" "unprognostic (2.64e-2)" "unprognostic (1.80e-1)" "unprognostic (4.90e-1)" "unprognostic (4.74e-2)" "unprognostic (1.35e-1)" "unprognostic (1.40e-2)" "unprognostic (4.02e-3)" "unprognostic (3.03e-2)" "unprognostic (2.32e-1)" "unprognostic (3.44e-2)" "potential prognostic unfavorable (2.15e-4)" "unprognostic (2.68e-2)" "unprognostic (6.74e-2)" "unprognostic (5.70e-2)" "unprognostic (2.17e-1)" "unprognostic (4.71e-2)" "unprognostic (8.58e-2)" "unprognostic (9.20e-3)" "unprognostic (2.28e-2)" "unprognostic (7.50e-3)" "unprognostic (6.48e-2)" "unprognostic (4.20e-1)" "unprognostic (1.24e-1)" "unprognostic (3.12e-2)" "unprognostic (5.84e-2)" "unprognostic (3.31e-1)" "unprognostic (5.37e-2)" "unprognostic (6.51e-2)" RRP1B "KIAA0179, Nnp1, PPP1R136, RRP1" ENSG00000160208 "Ribosomal RNA processing 1B" Q14684 21 43659560-43696079 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, mRNA processing, mRNA splicing, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 186.3;Early spermatids: 370.8;Late spermatids: 583.7;Rod photoreceptor cells: 306.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA017893, HPA020324" Supported Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No 9100 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 79: Photoreceptor cells - Phototransduction" 59 "Nucleoli, Nucleoli rim, Mitotic chromosome" Nucleoplasm "HPA017893: , HPA020324: " "unprognostic (3.87e-2)" "unprognostic (1.64e-2)" "unprognostic (6.19e-2)" "unprognostic (4.86e-3)" "unprognostic (1.40e-1)" "unprognostic (6.16e-2)" "unprognostic (3.80e-2)" "unprognostic (5.67e-3)" "unprognostic (1.36e-1)" "unprognostic (1.77e-2)" "potential prognostic favorable (1.71e-4)" "unprognostic (1.71e-1)" "unprognostic (1.08e-2)" "unprognostic (8.21e-3)" "unprognostic (1.88e-3)" "unprognostic (2.63e-3)" "potential prognostic unfavorable (1.09e-5)" "unprognostic (6.42e-2)" "unprognostic (1.08e-1)" "unprognostic (1.86e-2)" "unprognostic (5.28e-2)" "unprognostic (7.18e-2)" "unprognostic (1.40e-1)" "unprognostic (2.56e-2)" "unprognostic (1.76e-2)" "unprognostic (3.82e-2)" "unprognostic (1.67e-1)" "unprognostic (2.47e-1)" "unprognostic (2.92e-1)" "unprognostic (1.17e-3)" "unprognostic (1.67e-1)" RRP36 "C6orf153, dJ20C7.4" ENSG00000124541 "Ribosomal RNA processing 36" Q96EU6 6 43021623-43034156 "Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Megakaryocytes: 117.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029904, HPA029905" Uncertain Enhanced Nucleoplasm,Nucleoli Yes No "Cluster 10: Non-specific - Membrane trafficking" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 28: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 4 "Nucleoplasm, Nucleoli" "HPA029904: , HPA029905: " "unprognostic (1.38e-2)" "unprognostic (1.36e-2)" "unprognostic (8.37e-2)" "unprognostic (1.36e-1)" "unprognostic (3.55e-1)" "unprognostic (3.51e-1)" "unprognostic (8.34e-2)" "unprognostic (3.63e-2)" "potential prognostic unfavorable (6.22e-5)" "unprognostic (9.76e-3)" "unprognostic (7.82e-2)" "unprognostic (1.23e-1)" "potential prognostic unfavorable (4.98e-5)" "unprognostic (1.10e-3)" "unprognostic (4.48e-3)" "unprognostic (9.35e-3)" "unprognostic (8.41e-2)" "unprognostic (4.93e-2)" "unprognostic (8.41e-3)" "unprognostic (2.05e-1)" "unprognostic (4.65e-2)" "unprognostic (8.45e-2)" "unprognostic (3.33e-1)" "unprognostic (6.68e-2)" "unprognostic (3.22e-1)" "unprognostic (5.77e-2)" "unprognostic (1.03e-1)" "unprognostic (3.00e-1)" "unprognostic (1.27e-3)" "unprognostic (8.26e-2)" RRP7A "CGI-96, Rrp7" ENSG00000189306 "Ribosomal RNA processing 7 homolog A" Q9Y3A4 22 42508344-42519796 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" RNA-binding "Disease variant, Intellectual disability, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 147.3;Esophageal basal cells: 142.1;Extravillous trophoblasts: 148.1;Migrating cytotrophoblasts: 149.3;Syncytiotrophoblasts: 135.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001586, HPA046768" Approved Supported "Nucleoplasm,Nucleoli,Cell Junctions" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 64: Non-specific - Transcription" "Cluster 33: Neurons - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 17: Non-specific - RNA processing" 10 Nucleoli "Nucleoplasm, Cell Junctions" "HPA001586: , HPA046768: " "unprognostic (8.80e-2)" "unprognostic (6.58e-2)" "unprognostic (3.57e-1)" "unprognostic (2.76e-2)" "unprognostic (1.70e-1)" "unprognostic (2.97e-1)" "unprognostic (2.00e-1)" "unprognostic (1.61e-2)" "unprognostic (2.90e-1)" "unprognostic (4.81e-2)" "unprognostic (2.03e-2)" "unprognostic (4.39e-2)" "unprognostic (1.26e-3)" "validated prognostic unfavorable (2.16e-5)" "validated prognostic unfavorable (2.36e-4)" "unprognostic (5.93e-2)" "unprognostic (1.69e-2)" "unprognostic (6.19e-2)" "unprognostic (2.15e-2)" "unprognostic (1.31e-1)" "unprognostic (2.18e-1)" "unprognostic (1.59e-1)" "unprognostic (1.25e-2)" "unprognostic (1.55e-1)" "unprognostic (1.48e-1)" "unprognostic (3.75e-3)" "unprognostic (4.43e-1)" "unprognostic (9.11e-2)" "unprognostic (2.05e-1)" "unprognostic (1.58e-1)" "unprognostic (1.84e-2)" RRP8 "KIAA0409, NML" ENSG00000132275 "Ribosomal RNA processing 8" O43159 11 6595072-6603616 "Predicted intracellular proteins" "rRNA processing, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038487, HPA057562" Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 17: Non-specific - RNA processing" 83 "Nucleoplasm, Nucleoli, Cytosol" "HPA038487: , HPA057562: " "unprognostic (8.27e-3)" "unprognostic (7.46e-2)" "unprognostic (2.90e-1)" "unprognostic (1.08e-2)" "unprognostic (8.21e-2)" "unprognostic (1.92e-1)" "unprognostic (1.23e-1)" "unprognostic (7.04e-2)" "unprognostic (4.17e-2)" "unprognostic (7.64e-2)" "potential prognostic unfavorable (4.29e-5)" "unprognostic (1.83e-2)" "unprognostic (1.45e-2)" "unprognostic (1.98e-3)" "unprognostic (1.09e-1)" "unprognostic (1.31e-1)" "potential prognostic unfavorable (4.79e-4)" "unprognostic (1.97e-1)" "unprognostic (6.26e-2)" "unprognostic (6.45e-2)" "unprognostic (2.63e-2)" "unprognostic (2.72e-1)" "unprognostic (1.18e-1)" "unprognostic (2.84e-2)" "unprognostic (1.38e-1)" "unprognostic (1.93e-1)" "unprognostic (2.14e-1)" "unprognostic (9.34e-2)" "unprognostic (1.78e-1)" "unprognostic (2.90e-1)" "unprognostic (4.41e-2)" RRP9 "RNU3IP2, U3-55K" ENSG00000114767 "Ribosomal RNA processing 9, U3 small nucleolar RNA binding protein" O43818 3 51933429-51941904 "Essential proteins, Predicted intracellular proteins" "rRNA processing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 57.9;Esophageal basal cells: 55.7;Extravillous trophoblasts: 48.4;Suprabasal keratinocytes: 44.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038798 Uncertain Uncertain Nucleoplasm NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 24: Non-specific - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 17: Non-specific - RNA processing" 42 Nucleoplasm "HPA038798: " "unprognostic (9.57e-2)" "unprognostic (9.97e-2)" "unprognostic (1.67e-1)" "unprognostic (9.04e-3)" "unprognostic (1.37e-1)" "unprognostic (2.17e-1)" "unprognostic (3.10e-2)" "unprognostic (2.56e-1)" "unprognostic (2.04e-1)" "unprognostic (5.28e-3)" "unprognostic (3.17e-2)" "unprognostic (2.62e-2)" "unprognostic (1.25e-2)" "validated prognostic unfavorable (2.17e-4)" "validated prognostic unfavorable (2.80e-7)" "unprognostic (3.84e-2)" "potential prognostic unfavorable (5.31e-4)" "unprognostic (8.62e-2)" "unprognostic (1.68e-1)" "unprognostic (3.20e-1)" "unprognostic (1.48e-1)" "unprognostic (6.11e-2)" "unprognostic (6.74e-2)" "potential prognostic unfavorable (2.15e-4)" "unprognostic (8.12e-2)" "unprognostic (1.12e-1)" "unprognostic (1.45e-1)" "unprognostic (1.43e-1)" "unprognostic (1.85e-1)" "unprognostic (6.42e-2)" "unprognostic (1.01e-1)" RRS1 KIAA0112 ENSG00000179041 "Ribosome biogenesis regulator 1 homolog" Q15050 8 66429014-66430733 "Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 11.4;Fallopian secretory cells: 8.6;Megakaryocyte-Erythroid progenitors: 9.1;Suprabasal keratinocytes: 9.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055549, HPA060937" Approved Supported Nucleoli NA No "Cluster 30: Non-specific - DNA binding" "Cluster 24: Non-specific - Transcription" "Cluster 18: Non-specific - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 88 Nucleoli "HPA055549: , HPA060937: " "unprognostic (3.63e-2)" "unprognostic (7.07e-2)" "unprognostic (7.34e-2)" "potential prognostic unfavorable (5.61e-5)" "unprognostic (2.03e-2)" "unprognostic (9.79e-2)" "unprognostic (9.31e-2)" "unprognostic (1.46e-1)" "potential prognostic unfavorable (3.84e-4)" "unprognostic (5.43e-3)" "unprognostic (1.98e-1)" "unprognostic (2.76e-1)" "unprognostic (2.92e-3)" "unprognostic (2.60e-3)" "unprognostic (1.46e-2)" "unprognostic (2.17e-3)" "unprognostic (2.67e-2)" "unprognostic (2.79e-1)" "unprognostic (1.37e-2)" "unprognostic (3.63e-2)" "unprognostic (1.32e-1)" "unprognostic (3.22e-3)" "unprognostic (1.27e-1)" "unprognostic (2.04e-2)" "unprognostic (3.30e-1)" "unprognostic (2.19e-1)" "unprognostic (1.81e-1)" "unprognostic (2.12e-1)" "unprognostic (2.41e-1)" "unprognostic (7.55e-2)" "unprognostic (9.31e-3)" RS1 "RS, XLRS1" ENSG00000102104 "Retinoschisin 1" O15537 X 18639688-18672108 "Disease related genes, Human disease related genes, Potential drug targets, Predicted secreted proteins, Transporters" "Cell adhesion, Sensory transduction, Vision" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 203 "retina: 198.0" "Group enriched" "Detected in some" 12 "Cone photoreceptor cells: 339.5;Rod photoreceptor cells: 247.6" "Cell type enhanced" "Detected in single" "deep-layer corticothalamic and 6b: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Uterine cancer: 2.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA059546 Enhanced "Secreted in other tissues" "Cell adhesion" NA NA "Cluster 42: Retina - Visual perception" "Cluster 1: Neuronal - Visual perception" "Cluster 79: Photoreceptor cells - Phototransduction" "HPA059546: " RSAD1 "FLJ11164, HemW" ENSG00000136444 "Radical S-adenosyl methionine domain containing 1" Q9HA92 17 50478860-50485974 "Essential proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Tuft cells: 69.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA022436, HPA022967, HPA024459" Approved Approved Mitochondria NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 24: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 88: Proximal tubular cells - Transmembrane transport" 24 Mitochondria "HPA022436: , HPA022967: , HPA024459: " "unprognostic (2.15e-1)" "unprognostic (5.34e-2)" "unprognostic (1.71e-1)" "unprognostic (3.59e-2)" "unprognostic (1.65e-1)" "unprognostic (8.57e-2)" "unprognostic (1.90e-1)" "unprognostic (3.29e-3)" "unprognostic (9.78e-2)" "unprognostic (2.15e-1)" "unprognostic (4.79e-3)" "unprognostic (8.05e-3)" "unprognostic (4.77e-2)" "unprognostic (8.15e-2)" "unprognostic (1.69e-1)" "unprognostic (6.22e-2)" "unprognostic (6.68e-2)" "unprognostic (8.34e-2)" "unprognostic (4.16e-3)" "unprognostic (5.02e-3)" "unprognostic (3.32e-1)" "potential prognostic favorable (5.59e-5)" "unprognostic (2.41e-2)" "unprognostic (5.16e-2)" "unprognostic (3.68e-3)" "unprognostic (1.49e-1)" "unprognostic (1.55e-1)" "unprognostic (3.07e-1)" "unprognostic (4.07e-2)" "unprognostic (9.84e-2)" "unprognostic (1.62e-2)" RSAD2 "cig5, vig1, Viperin" ENSG00000134321 "Radical S-adenosyl methionine domain containing 2" Q8WXG1 2 6865557-6898239 "Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" Lyase Atherosclerosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 19.7" "Cell type enhanced" "Detected in many" "Colonocytes: 138.2;Endometrial ciliated cells: 47.7;Epididymal basal cells: 108.6;Epididymal efferent duct ciliated cells: 51.6;Foveolar cells: 93.8;Pancreatic islet cells: 64.1;Retinal pigment epithelial cells: 51.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 30.6;eosinophil: 43.3;neutrophil: 25.2" "Lineage enriched" "Detected in many" 6 "granulocytes: 43.3" "Low cancer specificity" "Detected in many" "Prostate - Fibroblasts" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA041160, HPA049409" Approved Approved "Nucleoli fibrillar center,Endoplasmic reticulum" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 9 "Nucleoli fibrillar center, Endoplasmic reticulum" "HPA041160: , HPA049409: " "unprognostic (1.59e-1)" "unprognostic (1.07e-1)" "unprognostic (6.08e-2)" "unprognostic (2.67e-2)" "unprognostic (6.08e-2)" "unprognostic (7.66e-2)" "unprognostic (3.05e-1)" "unprognostic (1.73e-1)" "unprognostic (2.97e-1)" "unprognostic (9.96e-2)" "unprognostic (2.92e-2)" "unprognostic (2.01e-1)" "unprognostic (1.38e-1)" "unprognostic (1.34e-1)" "unprognostic (1.37e-2)" "unprognostic (1.95e-1)" "unprognostic (9.97e-3)" "unprognostic (2.28e-1)" "unprognostic (4.47e-2)" "unprognostic (1.08e-1)" "unprognostic (2.74e-1)" "unprognostic (1.16e-2)" "unprognostic (2.72e-2)" "unprognostic (3.08e-1)" "unprognostic (1.27e-1)" "potential prognostic favorable (5.04e-4)" "unprognostic (5.84e-2)" "unprognostic (5.61e-2)" "unprognostic (9.68e-3)" "unprognostic (9.92e-2)" "unprognostic (9.40e-3)" RSBN1 "FLJ11220, ROSBIN" ENSG00000081019 "Round spermatid basic protein 1" Q5VWQ0 1 113761832-113812476 "Predicted intracellular proteins" "Chromatin regulator, Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 209.7;Neutrophils: 285.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042124, HPA049484" Approved Approved Nucleoplasm NA NA "Cluster 41: Basophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 2: Neurons - Nucleosome" "Cluster 37: Non-specific - mRNA processing" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 56 Nucleoplasm "HPA042124: , HPA049484: " "unprognostic (2.06e-2)" "unprognostic (2.53e-1)" "unprognostic (2.41e-1)" "unprognostic (2.99e-2)" "unprognostic (3.91e-3)" "unprognostic (2.83e-2)" "unprognostic (1.36e-1)" "unprognostic (1.40e-1)" "unprognostic (5.40e-2)" "unprognostic (1.29e-2)" "validated prognostic favorable (4.73e-7)" "validated prognostic favorable (1.25e-5)" "unprognostic (2.61e-1)" "unprognostic (6.86e-2)" "unprognostic (3.75e-1)" "unprognostic (1.43e-1)" "unprognostic (3.34e-2)" "unprognostic (1.91e-1)" "unprognostic (5.48e-2)" "unprognostic (1.63e-1)" "unprognostic (3.75e-2)" "unprognostic (7.17e-2)" "unprognostic (2.12e-1)" "unprognostic (9.97e-2)" "unprognostic (2.31e-3)" "unprognostic (1.13e-1)" "unprognostic (1.40e-1)" "unprognostic (1.21e-1)" "unprognostic (1.67e-1)" "unprognostic (8.90e-2)" "unprognostic (9.15e-2)" RSBN1L "FLJ42526, FLJ45813, MGC71764" ENSG00000187257 "Round spermatid basic protein 1 like" Q6PCB5 7 77696459-77783022 "Cancer-related genes, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 54.6" "Lineage enriched" "Detected in all" 4 "granulocytes: 54.6" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020406, HPA020413" Approved Supported "Nuclear speckles,Plasma membrane" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 16: Non-specific - Transcription" "Cluster 39: Non-specific - Transcription" "Cluster 24: Neutrophils - Innate immunity signal integration" 33 "Nuclear speckles" "Plasma membrane" "HPA020406: , HPA020413: " "potential prognostic favorable (1.77e-4)" "unprognostic (1.98e-2)" "unprognostic (6.34e-2)" "unprognostic (5.88e-2)" "unprognostic (1.49e-1)" "unprognostic (1.10e-1)" "unprognostic (1.17e-1)" "unprognostic (1.84e-1)" "unprognostic (2.20e-2)" "unprognostic (8.29e-3)" "potential prognostic favorable (1.09e-5)" "unprognostic (1.74e-2)" "unprognostic (2.68e-1)" "unprognostic (6.16e-2)" "unprognostic (1.56e-1)" "unprognostic (3.80e-2)" "unprognostic (1.35e-1)" "unprognostic (4.45e-2)" "unprognostic (9.63e-2)" "unprognostic (2.89e-1)" "unprognostic (7.65e-3)" "unprognostic (1.31e-2)" "unprognostic (3.87e-2)" "unprognostic (1.14e-1)" "unprognostic (1.39e-1)" "unprognostic (6.04e-2)" "unprognostic (3.18e-2)" "unprognostic (1.88e-1)" "unprognostic (1.44e-1)" "unprognostic (4.37e-1)" "unprognostic (9.87e-2)" RSC1A1 RS1 ENSG00000215695 "Regulator of solute carriers 1" Q92681 1 15659713-15662033 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 1.5;Microglia: 1.3" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in some" "Stomach Adenocarcinoma (TCGA): 3.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027813, HPA028676" Approved Supported "Nucleoplasm,Nuclear bodies,Golgi apparatus,Vesicles,Plasma membrane,Primary cilium,Primary cilium tip,Basal body" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 34: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 22: Non-specific - Basic cellular functions" 3 "Golgi apparatus, Vesicles, Plasma membrane" "Nucleoplasm, Nuclear bodies, Primary cilium, Primary cilium tip, Basal body" "HPA027813: , HPA028676: " "unprognostic (4.48e-1)" "unprognostic (4.54e-2)" "unprognostic (6.22e-2)" "unprognostic (3.24e-1)" "unprognostic (1.08e-2)" "unprognostic (1.63e-1)" "unprognostic (1.88e-2)" "unprognostic (9.25e-2)" "unprognostic (3.46e-2)" "unprognostic (1.89e-2)" "unprognostic (1.75e-1)" "potential prognostic favorable (7.50e-4)" "unprognostic (9.29e-2)" "unprognostic (7.62e-1)" RSF1 "HBXAP, p325, RSF-1, XAP8" ENSG00000048649 "Remodeling and spacing factor 1" Q96T23 11 77660009-77820869 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Endothelial cells, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022626, HPA046129, HPA057547, HPA064567" Supported Enhanced Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 38 Nucleoplasm "CAB022626: , HPA046129: , HPA057547: , HPA064567: " "unprognostic (2.76e-1)" "unprognostic (2.54e-1)" "unprognostic (7.64e-2)" "unprognostic (5.23e-3)" "unprognostic (3.12e-1)" "unprognostic (4.88e-3)" "unprognostic (6.01e-3)" "unprognostic (1.81e-2)" "unprognostic (1.10e-1)" "potential prognostic unfavorable (8.24e-5)" "potential prognostic favorable (6.41e-6)" "unprognostic (2.47e-2)" "unprognostic (1.09e-1)" "unprognostic (3.40e-2)" "unprognostic (9.05e-2)" "unprognostic (6.30e-2)" "unprognostic (2.46e-3)" "unprognostic (1.63e-1)" "unprognostic (4.85e-2)" "unprognostic (2.08e-1)" "unprognostic (2.11e-1)" "validated prognostic unfavorable (1.18e-4)" "validated prognostic unfavorable (2.57e-4)" "unprognostic (2.20e-1)" "unprognostic (2.34e-2)" "unprognostic (8.36e-2)" "unprognostic (1.07e-1)" "unprognostic (4.29e-1)" "unprognostic (2.23e-1)" "unprognostic (1.00e-1)" "unprognostic (2.58e-1)" RSKR "FLJ25006, SgK494" ENSG00000167524 "Ribosomal protein S6 kinase related" 17 28455752-28614197 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "retina: 5.3" "Cell type enhanced" "Detected in many" "Adipocytes: 8.7;Cardiomyocytes: 16.5;Cone photoreceptor cells: 14.5;Early spermatids: 20.0;Enterocytes: 15.3;Epicardial cells: 13.6;Late spermatids: 29.2;Retinal ganglion cells: 7.7;Retinal horizontal cells: 10.0;Rod photoreceptor cells: 20.6;Tuft cells: 11.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Testicular Germ Cell Tumor (TCGA): 1.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 4.4" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA046590 Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "Vesicles, Plasma membrane" Nucleoplasm "HPA046590: " "unprognostic (2.03e-2)" "unprognostic (1.32e-2)" "unprognostic (1.83e-2)" "unprognostic (1.67e-1)" RSL1D1 "CSIG, DKFZP564M182, L12, PBK1, UTP30" ENSG00000171490 "Ribosomal L1 domain containing 1" O76021 16 11833850-11851580 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043483 Supported Approved "Nucleoli rim,Mitotic chromosome,Vesicles,Primary cilium" Yes No 400000 "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 54: Non-specific - Transcription" "Cluster 15: Non-specific - Protein processing" 106 "Nucleoli rim, Mitotic chromosome" "Vesicles, Primary cilium" "HPA043483: " "unprognostic (4.69e-3)" "unprognostic (7.03e-3)" "unprognostic (1.67e-1)" "unprognostic (7.52e-2)" "unprognostic (2.11e-2)" "unprognostic (3.52e-2)" "unprognostic (2.56e-1)" "unprognostic (1.88e-1)" "unprognostic (2.01e-2)" "unprognostic (6.78e-2)" "potential prognostic favorable (3.68e-7)" "unprognostic (2.61e-2)" "unprognostic (1.43e-3)" "unprognostic (1.32e-2)" "unprognostic (5.49e-3)" "unprognostic (7.94e-2)" "unprognostic (1.29e-3)" "unprognostic (2.25e-1)" "unprognostic (8.60e-2)" "unprognostic (6.52e-2)" "unprognostic (2.96e-2)" "unprognostic (4.72e-3)" "unprognostic (2.27e-2)" "unprognostic (1.04e-1)" "potential prognostic favorable (5.20e-4)" "unprognostic (3.44e-1)" "unprognostic (1.94e-1)" "unprognostic (2.56e-2)" "unprognostic (1.55e-1)" "unprognostic (5.41e-3)" "potential prognostic favorable (6.18e-4)" RSL24D1 "C15orf15, HRP-L30-iso, L30, RPL24, RPL24L" ENSG00000137876 "Ribosomal L24 domain containing 1" Q9UHA3 15 55180806-55197049 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062724, HPA063392" Enhanced Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 46 "Nucleoplasm, Nucleoli, Nucleoli rim" "HPA062724: , HPA063392: " "unprognostic (2.36e-3)" "unprognostic (3.98e-2)" "unprognostic (1.20e-2)" "unprognostic (1.96e-1)" "unprognostic (8.94e-2)" "unprognostic (7.27e-2)" "unprognostic (2.35e-2)" "unprognostic (8.04e-2)" "potential prognostic unfavorable (1.51e-4)" "unprognostic (4.83e-2)" "validated prognostic favorable (4.95e-7)" "validated prognostic favorable (3.20e-4)" "unprognostic (2.00e-2)" "unprognostic (2.58e-3)" "potential prognostic unfavorable (5.58e-5)" "potential prognostic unfavorable (4.45e-4)" "unprognostic (5.66e-3)" "unprognostic (2.04e-2)" "unprognostic (4.70e-2)" "unprognostic (4.09e-2)" "unprognostic (2.23e-3)" "potential prognostic unfavorable (7.00e-4)" "unprognostic (4.89e-3)" "unprognostic (2.00e-2)" "unprognostic (8.74e-2)" "unprognostic (2.67e-1)" "unprognostic (2.23e-2)" "unprognostic (1.99e-2)" "unprognostic (1.22e-1)" "unprognostic (1.77e-2)" "unprognostic (5.14e-2)" RSPH1 "CILD24, FLJ32753, RSP44, RSPH10A, TSGA2" ENSG00000160188 "Radial spoke head component 1" Q8WYR4 21 42472486-42496246 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Meiosis "Ciliopathy, Disease variant, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 108.8;fallopian tube: 151.8" "Group enriched" "Detected in many" 5 "Endometrial ciliated cells: 1007.0;Ependymal cells: 586.4;Epididymal efferent duct ciliated cells: 813.4;Fallopian tube ciliated cells: 1410.0;Respiratory ciliated cells: 1689.5" "Cell type enriched" "Detected in all" 10 "ependymal cell: 653.9" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 58.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 10 "plasmacytoid DC: 3.0" "Lineage enriched" "Detected in single" 10 "dendritic cells: 3.0" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016816, HPA017382" Enhanced Uncertain "Centrosome,Basal body,Acrosome,Mid piece" NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 107: Ciliated cells - Cilia assembly & function" 1 "Centrosome, Basal body, Mid piece" Acrosome "HPA016816: , HPA017382: " "unprognostic (3.99e-2)" "unprognostic (2.91e-3)" "unprognostic (3.42e-2)" "unprognostic (3.04e-1)" "unprognostic (2.86e-3)" "unprognostic (2.91e-1)" "unprognostic (6.40e-2)" "unprognostic (9.50e-3)" "unprognostic (5.82e-2)" "unprognostic (1.22e-1)" "unprognostic (1.23e-2)" "unprognostic (9.84e-2)" "unprognostic (3.14e-1)" "unprognostic (2.60e-1)" "unprognostic (1.94e-1)" "unprognostic (1.62e-1)" "unprognostic (2.25e-1)" "unprognostic (3.00e-1)" "unprognostic (1.37e-2)" "unprognostic (2.43e-2)" "unprognostic (1.03e-1)" "unprognostic (6.08e-2)" "unprognostic (4.51e-2)" "unprognostic (3.40e-2)" "unprognostic (1.94e-2)" "unprognostic (8.70e-2)" "unprognostic (5.69e-2)" RSPH10B ENSG00000155026 "Radial spoke head 10 homolog B" P0C881 7 5925550-5970689 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "fallopian tube: 7.9;testis: 18.2" "Cell type enriched" "Detected in some" 4 "Late spermatids: 236.3" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 3.4;ependymal cell: 7.8" "Group enriched" "Detected in some" 8 "Prostate Adenocarcinoma (TCGA): 4.1;Testicular Germ Cell Tumor (TCGA): 2.6;Uterine Corpus Endometrial Carcinoma (TCGA): 5.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" HPA049182 Supported Approved "Plasma membrane,Microtubules,Primary cilium,Cytosol" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 67: Non-specific - Unknown function" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 1 "Primary cilium" "Plasma membrane, Microtubules, Cytosol" "HPA049182: " "unprognostic (1.15e-2)" "unprognostic (1.86e-2)" "unprognostic (2.15e-1)" "unprognostic (1.35e-1)" RSPH10B2 ENSG00000169402 "Radial spoke head 10 homolog B2" B2RC85 7 6754103-6799365 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 9.5;testis: 18.2" "Cell type enhanced" "Detected in some" "Early spermatids: 29.3;Endometrial ciliated cells: 11.0;Ependymal cells: 29.3;Epicardial cells: 9.1;Epididymal efferent duct ciliated cells: 9.2;Fallopian tube ciliated cells: 21.9;Late primary spermatocytes: 23.2;Late spermatids: 113.0;Respiratory ciliated cells: 24.6" "Cell type enriched" "Detected in many" 9 "ependymal cell: 27.6" "Cancer enhanced" "Detected in single" "Testicular Germ Cell Tumor (TCGA): 1.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" HPA049182 Supported Approved "Plasma membrane,Microtubules,Primary cilium,Cytosol" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" "Primary cilium" "Plasma membrane, Microtubules, Cytosol" "HPA049182: " "unprognostic (1.65e-1)" "unprognostic (7.09e-3)" "unprognostic (1.42e-1)" RSPH14 RTDR1 ENSG00000100218 "Radial spoke head 14 homolog" Q9UHP6 22 23059415-23145021 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 11.6;testis: 24.9" "Cell type enhanced" "Detected in many" "Early spermatids: 190.6;Ependymal cells: 46.0;Epididymal efferent duct ciliated cells: 48.7;Fallopian tube ciliated cells: 62.8;Late primary spermatocytes: 85.1;Late spermatids: 415.5;Megakaryocytes: 68.0;Platelets: 63.4;Respiratory ciliated cells: 138.1" "Cell type enriched" "Detected in many" 5 "ependymal cell: 53.9" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 20.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "neutrophil: 7.8" "Lineage enriched" "Detected in many" 4 "granulocytes: 7.8" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA018420, HPA050425" Approved Uncertain Nucleoli NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 15: Kidney cancer - Membrane components" "Cluster 107: Ciliated cells - Cilia assembly & function" 42 Nucleoli "HPA018420: , HPA050425: " "unprognostic (4.43e-2)" "unprognostic (3.60e-1)" "unprognostic (4.60e-3)" "unprognostic (1.87e-1)" "unprognostic (2.07e-1)" "unprognostic (3.74e-1)" "potential prognostic unfavorable (7.72e-4)" "unprognostic (1.92e-1)" "unprognostic (3.36e-2)" "unprognostic (1.26e-2)" "potential prognostic favorable (1.68e-7)" "potential prognostic unfavorable (5.22e-5)" "unprognostic (1.84e-1)" "unprognostic (2.16e-1)" "unprognostic (1.95e-1)" "unprognostic (5.38e-2)" "unprognostic (3.69e-2)" "unprognostic (1.48e-2)" "unprognostic (6.73e-2)" "unprognostic (1.33e-2)" "unprognostic (1.38e-1)" "unprognostic (2.61e-2)" "unprognostic (1.05e-1)" "unprognostic (2.47e-1)" "unprognostic (1.71e-1)" "unprognostic (1.42e-1)" RSPH3 "dJ111C20.1, RSHL2, RSP3" ENSG00000130363 "Radial spoke head 3" 6 158972871-159000202 "Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 160.5;Endometrial ciliated cells: 206.2;Ependymal cells: 176.0;Esophageal apical cells: 187.5;Respiratory ciliated cells: 313.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 10.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039109 Approved Approved "Plasma membrane,Cytosol,Flagellar centriole,Mid piece,Annulus" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" "Plasma membrane, Flagellar centriole, Mid piece, Annulus" Cytosol "HPA039109: " "unprognostic (2.29e-1)" "unprognostic (2.48e-3)" "unprognostic (1.14e-1)" "potential prognostic unfavorable (7.34e-5)" "unprognostic (1.32e-1)" "unprognostic (5.88e-2)" "unprognostic (1.88e-1)" "unprognostic (3.29e-2)" "unprognostic (3.48e-2)" "unprognostic (1.51e-3)" "potential prognostic favorable (3.26e-6)" "unprognostic (8.15e-3)" "unprognostic (4.15e-2)" "unprognostic (1.40e-3)" "unprognostic (1.72e-1)" "unprognostic (6.30e-2)" "unprognostic (6.84e-2)" "unprognostic (2.12e-1)" "unprognostic (9.56e-2)" "unprognostic (1.76e-2)" "unprognostic (2.60e-2)" "unprognostic (5.24e-2)" "unprognostic (8.72e-3)" "unprognostic (2.63e-1)" "unprognostic (3.48e-2)" "unprognostic (4.87e-2)" "unprognostic (1.01e-1)" "unprognostic (2.31e-1)" "unprognostic (2.29e-1)" "unprognostic (8.38e-2)" "unprognostic (2.00e-1)" RSPH4A "CILD11, dJ412I7.1, FLJ37974, RSHL3, RSPH6B" ENSG00000111834 "Radial spoke head component 4A" Q5TD94 6 116616479-116632985 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "choroid plexus: 22.0;fallopian tube: 35.0" "Group enriched" "Detected in many" 4 "Endometrial ciliated cells: 109.3;Ependymal cells: 90.6;Epididymal efferent duct ciliated cells: 93.2;Fallopian tube ciliated cells: 263.2;Respiratory ciliated cells: 317.0" "Group enriched" "Detected in many" 16 "choroid plexus epithelial cell: 26.2;ependymal cell: 102.9" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 6.7" "Region enhanced" "Detected in all" "choroid plexus: 46.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "midbrain: 19.3" "HPA031196, HPA031197, HPA031198" Enhanced Approved "Connecting piece,Flagellar centriole,Annulus" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" "Connecting piece, Flagellar centriole" Annulus "HPA031196: , HPA031197: , HPA031198: " "unprognostic (1.10e-1)" "unprognostic (1.58e-1)" "unprognostic (1.71e-1)" "unprognostic (3.08e-3)" "unprognostic (4.40e-2)" "unprognostic (3.11e-1)" "unprognostic (2.12e-1)" "unprognostic (3.27e-1)" "unprognostic (2.12e-2)" "unprognostic (2.78e-1)" "unprognostic (1.97e-1)" RSPH6A "RSHL1, RSP4, RSP6, RSPH4B" ENSG00000104941 "Radial spoke head 6 homolog A" Q9H0K4 19 45795713-45815308 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "testis: 28.3" "Group enriched" "Detected in some" 6 "Early spermatids: 79.0;Late primary spermatocytes: 157.3" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "Thyroid Carcinoma (TCGA): 3.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA045382 Enhanced NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 2 "HPA045382: " "unprognostic (4.80e-2)" RSPH9 "C6orf206, CILD12, FLJ30845, MRPS18AL1" ENSG00000172426 "Radial spoke head component 9" Q9H1X1 6 43645036-43672600 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 8.1;fallopian tube: 7.8;testis: 14.5" "Cell type enhanced" "Detected in many" "Early spermatids: 205.0;Endometrial ciliated cells: 111.0;Ependymal cells: 70.7;Epididymal efferent duct ciliated cells: 105.3;Fallopian tube ciliated cells: 253.2;Late primary spermatocytes: 256.8;Platelets: 122.5;Respiratory ciliated cells: 456.9" "Cell type enhanced" "Detected in many" "ependymal cell: 76.9" "Group enriched" "Detected in many" 7 "Prostate Adenocarcinoma (TCGA): 12.5;Uterine Corpus Endometrial Carcinoma (TCGA): 17.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells, Prostate - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031703 Enhanced Approved "Acrosome,Equatorial segment,Mid piece,Principal piece,End piece" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 5: Rhabdoid - Unknown function" "Cluster 107: Ciliated cells - Cilia assembly & function" 7 "Mid piece, Principal piece, End piece" "Acrosome, Equatorial segment" "HPA031703: " "unprognostic (6.14e-2)" "unprognostic (4.51e-2)" "unprognostic (6.50e-2)" "potential prognostic unfavorable (5.74e-4)" "unprognostic (6.84e-2)" "unprognostic (1.71e-1)" "unprognostic (2.37e-3)" "unprognostic (1.14e-2)" "unprognostic (1.11e-1)" "unprognostic (2.63e-1)" "unprognostic (4.48e-3)" "unprognostic (1.61e-1)" "unprognostic (3.96e-2)" "unprognostic (1.96e-1)" "unprognostic (2.42e-1)" "unprognostic (1.70e-1)" "unprognostic (1.19e-1)" RSPO1 "FLJ40906, RSPONDIN" ENSG00000169218 "R-spondin 1" Q2MKA7 1 37611350-37634892 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Sensory transduction, Wnt signaling pathway" Heparin-binding "Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 23.4;endometrium 1: 34.1;fallopian tube: 20.8" "Cell type enhanced" "Detected in some" "Breast secretory cells: 8.7;Epicardial cells: 20.5;Fallopian secretory cells: 23.2;Fibroblasts: 9.1;Medullary thymic epithelial cells: 4.8;Mesothelial cells: 43.7;Smooth muscle cells: 19.0" "Cell type enhanced" "Detected in single" "cerebellar inhibitory: 1.9" "Cancer enriched" "Detected in some" 8 "Ovary Serous Cystadenocarcinoma (TCGA): 17.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells, Prostate - Fibroblasts, Spleen - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA046154, HPA062923" Uncertain Approved Vesicles "Secreted in female reproductive system" Other NA NA 21000 "Cluster 75: Ovary - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 108: Fibroblasts - ECM organization" 6 Vesicles "HPA046154: , HPA062923: " "unprognostic (6.40e-2)" "unprognostic (8.77e-2)" "unprognostic (2.16e-1)" "unprognostic (9.97e-2)" "unprognostic (4.01e-2)" "unprognostic (1.91e-1)" RSPO2 MGC35555 ENSG00000147655 "R-spondin 2" Q6UXX9 8 107899316-108083642 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Sensory transduction, Wnt signaling pathway" "Developmental protein, Heparin-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 14.5;intestine: 12.7;placenta: 16.5" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 34.5;Brain inhibitory neurons: 23.0;Ependymal cells: 59.1;Epicardial cells: 36.4;Fibroblasts: 22.1;Oocytes: 188.8;Other brain neurons: 89.9" "Cell type enhanced" "Detected in many" "MGE interneuron: 154.3;miscellaneous: 141.7" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 2.1" "Region enhanced" "Detected in all" "midbrain: 51.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Rhabdoid: 6.4" "Liver - Hepatic stellate cells, Lung - Fibroblasts_1, Pituitary gland - Corticotropes, Skin - Inner root sheath cells, Testis - Spermatogonia" "Group enriched" "Detected in many" 7 "amygdala: 7.9;cerebral cortex: 17.9;hippocampal formation: 21.3;white matter: 13.2" "Group enriched" "Detected in many" 4 "amygdala: 15.8;cerebral cortex: 14.5;hippocampal formation: 15.9;midbrain: 23.9;spinal cord: 14.5" "HPA024764, CAB025900, HPA053068" Uncertain "Secreted in other tissues" "Developmental protein" NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 53: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 108: Fibroblasts - ECM organization" 8 "CAB025900: , HPA024764: , HPA053068: " "unprognostic (2.20e-2)" "unprognostic (8.29e-2)" "unprognostic (2.20e-1)" "unprognostic (1.23e-1)" "unprognostic (1.32e-1)" "unprognostic (2.84e-1)" RSPO3 "FLJ14440, THSD2" ENSG00000146374 "R-spondin 3" Q9BXY4 6 127118671-127199481 "Cancer-related genes, Predicted secreted proteins" "Sensory transduction, Wnt signaling pathway" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 44.9" "Cell type enhanced" "Detected in many" "Adipocytes: 100.2;Brain excitatory neurons: 26.8;Corticotrophs: 36.4;Decidual stromal cells: 23.4;Endometrial secretory cells: 23.3;Fibro-adipogenic progenitors: 88.0;Fibroblasts: 93.7;Hepatic stellate cells: 25.8;Myonuclei: 90.2;Salivary myoepithelial cells: 31.3;Vascular endothelial cells: 35.4" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 90.0;hippocampal CA4: 115.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 7.4;Rhabdoid: 20.2" "Adipose subcutaneous - Smooth muscle cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblasts_2, Pancreas - Fibroblasts, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Spleen - Smooth muscle cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "hippocampal formation: 26.0" HPA029957 Uncertain "Secreted to blood" Other NA NA "Cluster 75: Ovary - Mixed function" "Cluster 29: Forebrain - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 108: Fibroblasts - ECM organization" 3 "HPA029957: " "unprognostic (7.63e-2)" "unprognostic (6.94e-2)" "unprognostic (2.22e-2)" "unprognostic (4.91e-3)" "unprognostic (8.12e-2)" "unprognostic (4.63e-2)" "potential prognostic favorable (6.74e-4)" "unprognostic (8.82e-2)" "potential prognostic favorable (4.04e-4)" "unprognostic (1.22e-2)" "unprognostic (1.27e-2)" "unprognostic (1.50e-3)" "unprognostic (1.97e-1)" "unprognostic (5.06e-2)" "unprognostic (9.04e-3)" "unprognostic (3.55e-2)" "unprognostic (3.16e-2)" "unprognostic (2.72e-1)" "unprognostic (1.52e-1)" "unprognostic (3.53e-1)" "unprognostic (3.85e-2)" "unprognostic (1.09e-2)" "unprognostic (1.21e-1)" "unprognostic (2.17e-1)" "unprognostic (3.41e-1)" RSPO4 "C20orf182, dJ824F16.3" ENSG00000101282 "R-spondin 4" Q2I0M5 20 958452-1002311 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Sensory transduction, Wnt signaling pathway" Heparin-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.2;lung: 11.6" "Cell type enhanced" "Detected in many" "Astrocytes: 20.0;Bergmann glia: 14.9;Choroid plexus epithelial cells: 12.2;Early spermatids: 20.5;Ependymal cells: 51.8;Epididymal efferent duct ciliated cells: 11.3;Gonadotrophs: 15.0;Late spermatids: 25.4;Other brain neurons: 21.7" "Cell type enhanced" "Detected in all" "ependymal cell: 70.0" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 9.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "thyroid cancer: 8.8" "Testis - Early spermatids, Testis - Late spermatids" "Region enhanced" "Detected in single" "basal ganglia: 1.2" "Not detected" "Not detected" HPA048887 Uncertain "Secreted in other tissues" Other NA NA "Cluster 2: Non-specific - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 109: Neurons - Neuronal signaling" 13 "HPA048887: " "unprognostic (7.36e-2)" "unprognostic (3.07e-1)" "unprognostic (1.02e-1)" "unprognostic (3.83e-2)" "unprognostic (1.53e-2)" "unprognostic (2.23e-1)" "potential prognostic unfavorable (2.70e-4)" "unprognostic (4.07e-2)" "unprognostic (5.81e-2)" "unprognostic (1.40e-2)" "unprognostic (1.80e-1)" "unprognostic (1.25e-2)" "unprognostic (2.20e-2)" RSPRY1 KIAA1972 ENSG00000159579 "Ring finger and SPRY domain containing 1" Q96DX4 16 57186137-57240469 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003729 Approved "Secreted to blood" "No annotated function" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 61: Non-specific - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 8 "HPA003729: " "unprognostic (2.11e-2)" "unprognostic (6.35e-3)" "unprognostic (2.11e-2)" "unprognostic (1.48e-2)" "unprognostic (9.66e-2)" "unprognostic (1.20e-1)" "unprognostic (8.27e-2)" "unprognostic (8.72e-3)" "unprognostic (1.13e-2)" "unprognostic (1.96e-2)" "potential prognostic favorable (1.77e-6)" "unprognostic (2.23e-1)" "unprognostic (1.90e-1)" "unprognostic (2.18e-2)" "unprognostic (2.82e-1)" "unprognostic (1.97e-2)" "unprognostic (2.28e-3)" "unprognostic (5.26e-2)" "unprognostic (6.91e-2)" "unprognostic (1.56e-1)" "unprognostic (1.40e-3)" "unprognostic (6.39e-2)" "potential prognostic unfavorable (4.24e-5)" "unprognostic (4.14e-2)" "unprognostic (9.50e-2)" "unprognostic (2.93e-2)" "unprognostic (1.57e-2)" "unprognostic (4.89e-2)" "unprognostic (3.29e-1)" "unprognostic (3.83e-2)" "unprognostic (6.91e-2)" RSRC1 "BM-011, MGC12197, SFRS21, SRrp53" ENSG00000174891 "Arginine and serine rich coiled-coil 1" Q96IZ7 3 158105855-158545730 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044792 Supported Approved "Nuclear speckles" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 19: Astrocytes - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 42 "Nuclear speckles" "HPA044792: " "unprognostic (1.91e-1)" "unprognostic (1.42e-3)" "unprognostic (6.08e-3)" "unprognostic (6.32e-2)" "unprognostic (7.44e-2)" "unprognostic (4.64e-1)" "unprognostic (2.89e-1)" "unprognostic (1.72e-2)" "unprognostic (1.55e-1)" "unprognostic (1.11e-2)" "unprognostic (1.35e-3)" "unprognostic (1.96e-1)" "unprognostic (1.74e-1)" "unprognostic (4.39e-3)" "unprognostic (1.26e-2)" "unprognostic (2.04e-3)" "potential prognostic unfavorable (9.01e-4)" "unprognostic (1.09e-2)" "unprognostic (5.10e-2)" "unprognostic (1.54e-1)" "potential prognostic unfavorable (2.05e-4)" "unprognostic (2.18e-2)" "unprognostic (5.03e-3)" "unprognostic (6.56e-2)" "unprognostic (1.54e-1)" "unprognostic (1.57e-2)" "unprognostic (3.26e-2)" "unprognostic (6.80e-2)" "unprognostic (5.74e-2)" "unprognostic (8.10e-2)" "unprognostic (8.73e-2)" RSRC2 FLJ11021 ENSG00000111011 "Arginine and serine rich coiled-coil 2" Q7L4I2 12 122503454-122527000 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 61.7" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040070, HPA048183" Enhanced Approved "Nucleoli fibrillar center,Nuclear speckles,Cytosol" No No "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 15: Bone marrow - Innate immune response" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 38: Non-specific - Transcription" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 9 "Nuclear speckles" "Nucleoli fibrillar center, Cytosol" "HPA040070: , HPA048183: " "unprognostic (3.13e-1)" "unprognostic (7.68e-2)" "unprognostic (1.95e-1)" "unprognostic (8.37e-2)" "unprognostic (4.29e-2)" "unprognostic (1.56e-1)" "unprognostic (1.71e-1)" "unprognostic (1.66e-2)" "unprognostic (1.08e-1)" "unprognostic (1.05e-2)" "potential prognostic favorable (1.20e-4)" "unprognostic (2.92e-3)" "unprognostic (9.02e-2)" "unprognostic (7.02e-3)" "unprognostic (1.02e-1)" "unprognostic (8.14e-2)" "unprognostic (5.90e-2)" "unprognostic (1.24e-1)" "unprognostic (5.28e-2)" "unprognostic (7.03e-2)" "unprognostic (3.46e-2)" "unprognostic (1.26e-2)" "unprognostic (2.16e-2)" "unprognostic (6.76e-2)" "unprognostic (1.82e-1)" "unprognostic (2.62e-1)" "unprognostic (1.18e-1)" "unprognostic (3.93e-2)" "unprognostic (2.66e-1)" "unprognostic (6.79e-2)" "unprognostic (2.78e-2)" RSRP1 "C1orf63, DJ465N24.2.1" ENSG00000117616 "Arginine and serine rich protein 1" Q9BUV0 1 25242249-25338213 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058992, HPA067651" Uncertain Approved Nucleoplasm NA NA "Cluster 41: Basophils - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 30: White matter - Myelination" "Cluster 47: Leukemia - Hemostasis" "Cluster 20: Non-specific - Transcription regulation" 8 Nucleoplasm "HPA058992: , HPA067651: " "unprognostic (1.03e-1)" "unprognostic (1.98e-2)" "unprognostic (1.91e-1)" "unprognostic (2.99e-1)" "unprognostic (7.35e-3)" "unprognostic (2.48e-2)" "unprognostic (1.11e-1)" "unprognostic (3.54e-2)" "unprognostic (2.99e-2)" "unprognostic (9.61e-2)" "unprognostic (2.67e-1)" "unprognostic (3.23e-1)" "unprognostic (1.52e-2)" "unprognostic (2.99e-1)" "unprognostic (1.55e-1)" "unprognostic (3.44e-2)" "unprognostic (1.57e-1)" "unprognostic (5.71e-1)" "unprognostic (1.67e-1)" "unprognostic (1.45e-1)" "unprognostic (1.00e-1)" "unprognostic (1.33e-3)" "unprognostic (7.43e-2)" "unprognostic (5.37e-2)" "potential prognostic unfavorable (6.36e-4)" "unprognostic (4.15e-1)" "unprognostic (2.33e-1)" "unprognostic (2.72e-1)" "unprognostic (4.40e-1)" RSU1 "FLJ31034, RSP-1" ENSG00000148484 "Ras suppressor protein 1" Q15404 10 16590611-16817463 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Megakaryocyte progenitors: 402.7;Megakaryocytes: 995.2;Oocytes: 419.1;Platelets: 736.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Smooth muscle cells, Prostate - Smooth muscle cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025927 Uncertain Approved Vesicles NA NA 27000000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 21: Non-specific - Metabolism" "Cluster 5: Rhabdoid - Unknown function" "Cluster 47: Platelets - Hemostasis" 16 Vesicles "HPA025927: " "unprognostic (7.59e-2)" "unprognostic (4.56e-2)" "unprognostic (1.64e-1)" "unprognostic (6.21e-3)" "unprognostic (2.72e-1)" "unprognostic (7.48e-2)" "unprognostic (3.15e-2)" "unprognostic (6.86e-3)" "unprognostic (1.87e-2)" "unprognostic (1.76e-2)" "potential prognostic favorable (7.06e-5)" "unprognostic (8.92e-2)" "unprognostic (2.26e-2)" "potential prognostic unfavorable (4.30e-5)" "unprognostic (1.06e-3)" "unprognostic (1.08e-1)" "unprognostic (6.12e-2)" "unprognostic (1.07e-1)" "unprognostic (3.78e-3)" "unprognostic (1.03e-1)" "unprognostic (5.62e-3)" "unprognostic (2.88e-2)" "unprognostic (1.86e-2)" "unprognostic (2.36e-1)" "unprognostic (4.43e-1)" "unprognostic (1.26e-2)" "unprognostic (8.77e-2)" "unprognostic (1.56e-2)" "unprognostic (1.64e-1)" "unprognostic (1.11e-2)" "unprognostic (1.02e-1)" RTBDN FLJ36353 ENSG00000132026 Retbindin Q9BSG5 19 12825478-12835428 "Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "retina: 267.5" "Group enriched" "Detected in some" 8 "Cone photoreceptor cells: 10.4;Rod photoreceptor cells: 18.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Pituitary gland - Gonadotropes, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA052511 Approved "Endoplasmic reticulum" "Secreted in other tissues" "No annotated function" NA NA "Cluster 42: Retina - Visual perception" "Cluster 14: Neurons - Synaptic function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 79: Photoreceptor cells - Phototransduction" "Endoplasmic reticulum" "HPA052511: " "unprognostic (1.62e-2)" "unprognostic (2.38e-2)" "unprognostic (5.84e-3)" "unprognostic (2.36e-3)" "unprognostic (1.06e-2)" "unprognostic (2.35e-1)" "unprognostic (1.48e-2)" "unprognostic (7.41e-2)" "unprognostic (1.02e-1)" "unprognostic (1.88e-1)" "unprognostic (2.15e-2)" "unprognostic (5.36e-2)" "unprognostic (8.40e-2)" "unprognostic (5.51e-2)" "unprognostic (9.65e-3)" RTCA "RPC, RTC1, RTCD1" ENSG00000137996 "RNA 3'-terminal phosphate cyclase" O00442 1 100266216-100292769 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 179.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027982, HPA027990, HPA028151, HPA028331" Uncertain Enhanced Nucleoplasm NA NA 18000 "Cluster 33: Non-specific - ATP binding" "Cluster 52: Non-specific - Cellular respiration" "Cluster 34: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 8: Non-specific - Secretory pathway" 1 Nucleoplasm "HPA027982: , HPA027990: , HPA028151: , HPA028331: " "unprognostic (1.21e-1)" "unprognostic (1.57e-2)" "unprognostic (2.55e-2)" "unprognostic (7.21e-3)" "unprognostic (1.01e-2)" "unprognostic (6.00e-2)" "unprognostic (1.89e-1)" "unprognostic (3.11e-3)" "potential prognostic unfavorable (9.06e-6)" "potential prognostic favorable (3.90e-5)" "unprognostic (6.40e-2)" "unprognostic (5.57e-2)" "potential prognostic unfavorable (4.07e-6)" "potential prognostic unfavorable (1.82e-4)" "unprognostic (1.28e-1)" "unprognostic (1.22e-1)" "unprognostic (3.22e-2)" "unprognostic (2.04e-1)" "unprognostic (5.38e-2)" "unprognostic (1.97e-1)" "unprognostic (1.00e-2)" "unprognostic (2.28e-1)" "unprognostic (2.28e-2)" "unprognostic (7.47e-2)" "unprognostic (1.82e-1)" "unprognostic (5.06e-2)" "unprognostic (5.09e-2)" "unprognostic (4.03e-2)" "unprognostic (4.06e-1)" RTCB "C22orf28, FAAP, HSPC117" ENSG00000100220 "RNA 2',3'-cyclic phosphate and 5'-OH ligase" Q9Y3I0 22 32387582-32412248 "Enzymes, Essential proteins, Predicted intracellular proteins" "tRNA processing" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Spleen - Macrophages, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000535, HPA001103" Supported Supported Nucleoplasm,Vesicles,Cytosol NA NA 94000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 76: Non-specific - Metabolism" "Cluster 27: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 51: Secretory epithelial cells - Mixed function" 75 Nucleoplasm "Vesicles, Cytosol" "HPA000535: , HPA001103: " "unprognostic (5.02e-1)" "unprognostic (7.76e-3)" "unprognostic (1.17e-1)" "unprognostic (5.99e-3)" "unprognostic (3.85e-2)" "unprognostic (5.73e-3)" "unprognostic (2.36e-2)" "unprognostic (6.89e-3)" "unprognostic (4.19e-3)" "potential prognostic favorable (1.26e-6)" "unprognostic (3.88e-3)" "unprognostic (2.74e-3)" "potential prognostic unfavorable (4.32e-4)" "unprognostic (5.39e-3)" "unprognostic (1.60e-1)" "unprognostic (6.03e-3)" "unprognostic (2.06e-3)" "unprognostic (1.93e-1)" "unprognostic (1.23e-2)" "unprognostic (1.74e-2)" "unprognostic (3.25e-1)" "unprognostic (7.46e-2)" "unprognostic (1.99e-2)" "unprognostic (2.51e-1)" "unprognostic (2.72e-1)" "unprognostic (9.92e-2)" "unprognostic (5.15e-2)" "unprognostic (1.02e-1)" "unprognostic (1.03e-2)" RTEL1 "bK3184A7.3, C20orf41, DKFZP434C013, KIAA1088, NHL, RTEL" ENSG00000258366 "Regulator of telomere elongation helicase 1" Q9NZ71 20 63657810-63696253 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Helicase, Hydrolase, Isomerase" "Disease variant, Dyskeratosis congenita" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 11.3;Bergmann glia: 7.8;Brain excitatory neurons: 13.8;Brain inhibitory neurons: 15.3;Choroid plexus epithelial cells: 7.8;Ependymal cells: 6.0;Epicardial cells: 6.8;Erythrocyte progenitors: 3.8;Microglia: 5.3;Oligodendrocyte progenitor cells: 6.6;Oligodendrocytes: 8.7;Other brain neurons: 10.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020622, HPA078328" Supported "Nucleoplasm,Nuclear membrane,Nuclear speckles" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 64: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 22: Non-specific - Basic cellular functions" 5 "Nuclear speckles" "Nucleoplasm, Nuclear membrane" "HPA020622: , HPA078328: " "unprognostic (4.18e-2)" "unprognostic (1.34e-2)" "unprognostic (1.98e-1)" "unprognostic (1.71e-2)" "unprognostic (1.03e-1)" "unprognostic (1.83e-2)" "unprognostic (2.78e-1)" "unprognostic (1.39e-2)" "unprognostic (4.84e-2)" "unprognostic (6.86e-2)" "unprognostic (2.07e-1)" "unprognostic (1.07e-1)" "unprognostic (1.63e-1)" "unprognostic (1.99e-2)" "unprognostic (2.20e-2)" "unprognostic (1.14e-2)" "unprognostic (1.11e-1)" "unprognostic (8.01e-2)" "unprognostic (1.85e-1)" "unprognostic (9.44e-2)" "unprognostic (1.30e-1)" "unprognostic (1.22e-1)" "potential prognostic unfavorable (1.66e-5)" "unprognostic (9.03e-2)" "unprognostic (1.66e-3)" "potential prognostic favorable (4.47e-4)" "unprognostic (9.08e-2)" "unprognostic (1.05e-1)" "unprognostic (2.02e-1)" "unprognostic (6.60e-2)" "unprognostic (4.12e-2)" RTF1 KIAA0252 ENSG00000137815 "RTF1 homolog, Paf1/RNA polymerase II complex component" Q92541 15 41408408-41483563 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 484.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006714, CAB079946, CAB079947" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 21 Nucleoplasm Cytosol "CAB079946: , CAB079947: , HPA006714: " "unprognostic (2.38e-2)" "unprognostic (7.75e-2)" "unprognostic (3.44e-1)" "unprognostic (2.21e-1)" "unprognostic (2.82e-1)" "unprognostic (7.41e-2)" "unprognostic (8.41e-2)" "unprognostic (8.38e-2)" "unprognostic (2.33e-1)" "potential prognostic unfavorable (6.76e-4)" "unprognostic (3.80e-3)" "unprognostic (3.04e-3)" "unprognostic (1.75e-1)" "unprognostic (3.97e-2)" "unprognostic (4.17e-3)" "unprognostic (6.90e-2)" "unprognostic (4.60e-2)" "unprognostic (2.19e-1)" "potential prognostic favorable (3.01e-4)" "unprognostic (7.50e-2)" "unprognostic (7.82e-2)" "potential prognostic unfavorable (4.46e-4)" "unprognostic (4.55e-2)" "unprognostic (2.11e-1)" "unprognostic (3.37e-2)" "unprognostic (8.39e-2)" "unprognostic (2.18e-1)" "unprognostic (1.98e-1)" "unprognostic (2.32e-1)" "unprognostic (1.24e-1)" "unprognostic (2.07e-1)" RTF2 "C20orf43, CDAO5, HSPC164, RTFDC1" ENSG00000022277 "Replication termination factor 2" Q9BY42 20 56468585-56519449 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 272.2;Neutrophils: 563.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Smooth muscle cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053986 Approved Supported Nucleoplasm,Nucleoli NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 14 "Nucleoplasm, Nucleoli" "HPA053986: " "unprognostic (8.75e-2)" "unprognostic (4.19e-2)" "unprognostic (1.06e-1)" "unprognostic (3.07e-1)" "unprognostic (1.98e-1)" "unprognostic (4.90e-1)" "unprognostic (2.94e-1)" "unprognostic (2.88e-3)" "unprognostic (1.04e-2)" "potential prognostic favorable (1.80e-5)" "unprognostic (5.27e-2)" "unprognostic (9.34e-2)" "potential prognostic unfavorable (5.29e-7)" "unprognostic (3.96e-1)" "unprognostic (1.37e-2)" "unprognostic (1.06e-1)" "unprognostic (5.19e-2)" "unprognostic (1.47e-1)" "unprognostic (1.61e-2)" "unprognostic (8.67e-2)" "unprognostic (2.49e-2)" "unprognostic (8.85e-2)" "unprognostic (1.91e-2)" "unprognostic (6.08e-3)" "unprognostic (3.20e-2)" "unprognostic (7.45e-2)" "unprognostic (1.81e-1)" "unprognostic (1.94e-1)" "unprognostic (1.92e-1)" RTKN B5 ENSG00000114993 Rhotekin Q9BST9 2 74425835-74442422 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 114.0;liver: 120.9" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 85.2;Proximal tubule cells: 76.5" "Group enriched" "Detected in many" 4 "committed oligodendrocyte precursor: 93.9;oligodendrocyte: 85.9;oligodendrocyte precursor cell: 82.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "NK-cell: 2.3;plasmacytoid DC: 6.5" "Group enriched" "Detected in many" 4 "dendritic cells: 6.5;NK-cells: 2.3" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030259 Approved Approved Nucleoplasm,Mitochondria No No "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 65: Non-specific - Cell growth & division" 14 Mitochondria Nucleoplasm "HPA030259: " "unprognostic (1.70e-1)" "unprognostic (8.36e-2)" "unprognostic (5.12e-2)" "unprognostic (4.88e-3)" "unprognostic (8.11e-2)" "unprognostic (4.54e-1)" "unprognostic (3.84e-2)" "unprognostic (4.97e-3)" "potential prognostic unfavorable (7.55e-4)" "unprognostic (2.21e-2)" "unprognostic (4.75e-3)" "unprognostic (2.13e-1)" "unprognostic (1.93e-2)" "unprognostic (1.34e-2)" "unprognostic (3.84e-3)" "unprognostic (6.50e-3)" "unprognostic (1.07e-2)" "unprognostic (2.55e-1)" "unprognostic (1.21e-2)" "unprognostic (1.59e-1)" "unprognostic (1.04e-1)" "unprognostic (9.44e-2)" "unprognostic (2.47e-2)" "unprognostic (4.13e-2)" "unprognostic (2.75e-1)" "unprognostic (1.72e-1)" "unprognostic (6.09e-2)" "unprognostic (1.23e-1)" "unprognostic (4.78e-1)" "unprognostic (1.63e-1)" "unprognostic (1.53e-1)" RTKN2 "bA531F24.1, Em:AC024597.2, FLJ39352, PLEKHK1" ENSG00000182010 "Rhotekin 2" Q8IZC4 10 62183035-62268844 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "lung: 73.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 287.9;Early spermatids: 496.3;Esophageal apical cells: 392.6;Esophageal suprabasal cells: 90.0;Late primary spermatocytes: 310.3;Late spermatids: 136.1;Oocytes: 138.2" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 33.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 8 "T-reg: 16.7" "Lineage enriched" "Detected in single" 73 "T-cells: 16.7" "Low cancer specificity" "Detected in all" "Adipose visceral - T-cells, Adrenal gland - Mitotic cells (Adrenal gland), Lung - Alveolar cells type 1, Pituitary gland - Somatotropes, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA037946, HPA038446" Enhanced Approved Nucleoplasm,Mitochondria NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 13: Lung - Secretion" "Cluster 53: Neurons - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 9: T-cells - Adaptive immunity: Regulation" 2 Nucleoplasm Mitochondria "HPA037946: , HPA038446: " "unprognostic (1.77e-1)" "unprognostic (2.04e-1)" "unprognostic (1.28e-1)" "unprognostic (1.65e-2)" "unprognostic (2.07e-1)" "unprognostic (1.20e-1)" "unprognostic (2.49e-1)" "unprognostic (9.36e-3)" "unprognostic (9.83e-2)" "unprognostic (1.97e-2)" "unprognostic (9.72e-2)" "unprognostic (1.21e-1)" "unprognostic (2.03e-1)" "unprognostic (1.15e-1)" "unprognostic (1.09e-1)" "unprognostic (1.09e-2)" "unprognostic (2.22e-3)" "unprognostic (3.68e-3)" "unprognostic (1.61e-1)" "unprognostic (2.99e-1)" "unprognostic (1.01e-1)" "unprognostic (3.36e-2)" "unprognostic (6.91e-3)" "unprognostic (1.77e-1)" RTL1 "HUR1, Mar1, MART1, PEG11, SIRH2" ENSG00000254656 "Retrotransposon Gag like 1" A6NKG5 14 100879753-100903722 "Predicted membrane proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 1.5;brain: 4.2;placenta: 2.7" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 42.5;Fibro-adipogenic progenitors: 27.8;Fibroblasts: 22.2;Lactotrophs: 10.7;Medullary thymic epithelial cells: 21.6;Myosatellite cells: 79.6;Other brain neurons: 17.8;Retinal ganglion cells: 27.0;Salivary myoepithelial cells: 12.6;Somatotrophs: 21.9" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Skin Cutaneous Melanoma (TCGA): 2.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "Neuroblastoma: 51.0" "Adrenal gland - Adrenal medulla cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "HPA066979, HPA077601" Enhanced Approved Cytosol No NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" Cytosol "HPA066979: , HPA077601: " "unprognostic (4.52e-3)" "unprognostic (6.93e-3)" "unprognostic (5.65e-2)" RTL10 "BOP, C22orf29, FLJ21125" ENSG00000215012 "Retrotransposon Gag like 10" Q7L3V2 22 19846138-19854896 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "HPA000721, HPA001419" Uncertain NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 58: Skin - Keratinization" "Cluster 51: Neurons - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 80: Oligodendrocytes - Myelination" 10 "HPA000721: , HPA001419: " "unprognostic (1.19e-2)" "unprognostic (1.64e-1)" "unprognostic (4.43e-2)" "unprognostic (1.03e-1)" "unprognostic (2.14e-1)" "unprognostic (6.91e-2)" "unprognostic (3.62e-2)" "unprognostic (1.36e-2)" "unprognostic (1.52e-1)" "unprognostic (5.29e-3)" "unprognostic (1.73e-2)" "unprognostic (1.26e-1)" "unprognostic (4.99e-3)" "unprognostic (1.98e-1)" "unprognostic (1.51e-1)" "unprognostic (3.32e-1)" "unprognostic (2.44e-2)" "unprognostic (4.25e-2)" "unprognostic (4.94e-2)" "unprognostic (3.76e-2)" "unprognostic (5.23e-3)" "unprognostic (1.18e-1)" "unprognostic (1.31e-3)" "unprognostic (4.36e-2)" "unprognostic (3.31e-2)" "unprognostic (2.80e-2)" "unprognostic (2.98e-1)" "unprognostic (2.05e-2)" "unprognostic (1.09e-1)" RTL3 "FLJ38865, Mar3, Mart3, SIRH9, ZCCHC5, ZHC5" ENSG00000179300 "Retrotransposon Gag like 3" Q8N8U3 X 78656068-78659328 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "blood vessel: 1.5" "Cell type enhanced" "Detected in single" "Leydig cells: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 1.2;liver cancer: 1.5" "Region enriched" "Detected in single" 9 "hippocampal formation: 2.8" "HPA051991, HPA053174, HPA075136" Uncertain Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 72: Neuronal - Signal transduction" "Cluster 108: Fibroblasts - ECM organization" Nucleoplasm "Golgi apparatus, Plasma membrane" "HPA051991: , HPA053174: , HPA075136: " RTL4 "FLJ46608, Mar4, Mart4, SIRH11, ZCCHC16" ENSG00000187823 "Retrotransposon Gag like 4" Q6ZR62 X 112083016-112457514 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 10.6;Cholangiocytes: 15.7;Epicardial cells: 9.1;Hepatocytes: 28.4;Pancreatic duct cells: 30.1;Pituitary stem cells: 50.2;Sertoli cells: 7.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "Testicular Germ Cell Tumor (TCGA): 2.2;Thyroid Carcinoma (TCGA): 5.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA003272 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 1 Nucleoplasm "Plasma membrane, Cytosol" "HPA003272: " "unprognostic (1.81e-1)" "unprognostic (1.27e-2)" RTL5 "KIAA2001, Mar5, Mart5, RGAG4, SIRH8" ENSG00000242732 "Retrotransposon Gag like 5" Q5HYW3 X 72127110-72131915 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 9.4" "Cell type enhanced" "Detected in many" "Corticotrophs: 25.1;Gonadotrophs: 12.2;Lactotrophs: 15.0;Neuroendocrine cells: 11.6;Pancreatic islet cells: 18.2;Somatotrophs: 14.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 5.6" "Kidney - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003652 Approved Approved Nucleoplasm NA NA "Cluster 64: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" Nucleoplasm "HPA003652: " "unprognostic (2.69e-1)" "unprognostic (3.97e-2)" "unprognostic (6.91e-2)" "unprognostic (4.00e-2)" "unprognostic (3.52e-1)" "unprognostic (1.05e-1)" "unprognostic (2.37e-1)" RTL6 "dJ1033E15.2, DKFZp761O17121, LDOC1L, Mar6, Mart6, SIRH3" ENSG00000188636 "Retrotransposon Gag like 6" Q6ICC9 22 44492583-44498233 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 41.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005697 Approved Approved "Nuclear speckles,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 65: Brain - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 2 "Nuclear speckles" Cytosol "HPA005697: " "unprognostic (5.10e-2)" "unprognostic (2.62e-1)" "unprognostic (2.34e-1)" "unprognostic (3.48e-2)" "unprognostic (2.48e-2)" "unprognostic (1.09e-2)" "unprognostic (3.18e-2)" "unprognostic (2.77e-1)" "unprognostic (2.65e-2)" "potential prognostic favorable (1.97e-7)" "unprognostic (3.64e-3)" "unprognostic (9.82e-2)" "unprognostic (5.35e-3)" "unprognostic (1.25e-1)" "unprognostic (2.94e-1)" "unprognostic (2.98e-2)" "potential prognostic favorable (8.12e-4)" "unprognostic (6.42e-2)" "unprognostic (1.37e-1)" "unprognostic (2.94e-1)" "unprognostic (5.59e-2)" "unprognostic (4.89e-2)" "unprognostic (7.10e-3)" "unprognostic (3.07e-3)" "unprognostic (5.25e-2)" "unprognostic (1.85e-1)" "unprognostic (7.45e-2)" "unprognostic (1.29e-1)" "unprognostic (1.01e-2)" RTL8A "CXX1b, DKFZP564B147, FAM127B, MAR8A, SIRH6" ENSG00000203950 "Retrotransposon Gag like 8A" Q9BWD3 X 135050932-135052196 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 158.7;Esophageal basal cells: 148.2;Esophageal suprabasal cells: 187.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 74: Non-specific - Signal transduction" "Cluster 6: Non-specific - Immune response" "Cluster 36: Non-specific - mRNA processing" "Cluster 85: Squamous epithelial cells - Keratinization" 6 "unprognostic (2.43e-1)" "unprognostic (3.88e-3)" "unprognostic (1.18e-3)" "unprognostic (3.82e-3)" "unprognostic (2.05e-2)" "unprognostic (8.41e-2)" "unprognostic (6.43e-3)" "unprognostic (1.47e-2)" "unprognostic (1.40e-1)" "unprognostic (4.30e-3)" "unprognostic (1.80e-1)" "unprognostic (1.25e-1)" "potential prognostic unfavorable (6.74e-6)" "unprognostic (5.95e-2)" "unprognostic (3.39e-3)" "unprognostic (3.79e-1)" "unprognostic (9.54e-3)" "unprognostic (2.19e-3)" "unprognostic (1.77e-3)" "unprognostic (4.63e-2)" "unprognostic (3.86e-2)" "unprognostic (1.70e-1)" "unprognostic (2.65e-1)" "potential prognostic favorable (4.34e-4)" "unprognostic (2.03e-2)" "unprognostic (2.00e-1)" "unprognostic (1.64e-1)" "unprognostic (4.84e-2)" "unprognostic (3.33e-2)" RTL8B "CXX1c, FAM127C, MAR8B, SIRH4" ENSG00000212747 "Retrotransposon Gag like 8B" Q17RB0 X 135020513-135022542 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 128.0;Decidual stromal cells: 38.1;Esophageal apical cells: 37.4;Esophageal basal cells: 41.1;Esophageal suprabasal cells: 57.9;Migrating cytotrophoblasts: 76.2" "Cell type enhanced" "Detected in many" "vascular associated smooth muscle cell: 13.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Liver - Vascular endothelial cells, Prostate - Smooth muscle cells" NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 6: Non-specific - Immune response" "Cluster 36: Non-specific - mRNA processing" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 11 "unprognostic (1.15e-1)" "potential prognostic unfavorable (9.46e-5)" "unprognostic (7.62e-3)" "unprognostic (1.08e-2)" "unprognostic (2.38e-1)" "unprognostic (2.65e-1)" "unprognostic (1.21e-1)" "unprognostic (3.59e-2)" "unprognostic (9.25e-2)" "unprognostic (2.09e-3)" "unprognostic (1.75e-1)" "unprognostic (7.83e-2)" "unprognostic (4.03e-3)" "unprognostic (2.92e-2)" "unprognostic (3.70e-2)" "unprognostic (4.48e-2)" "unprognostic (2.41e-1)" "unprognostic (4.34e-3)" "unprognostic (6.61e-2)" "unprognostic (9.51e-2)" "unprognostic (3.32e-2)" "unprognostic (4.04e-2)" "unprognostic (4.22e-2)" "unprognostic (2.20e-2)" "unprognostic (1.56e-2)" "potential prognostic unfavorable (9.60e-4)" "unprognostic (1.29e-1)" "unprognostic (2.33e-2)" "unprognostic (2.55e-1)" RTL8C "CXX1, FAM127A, Mar8, MAR8C, Mart8, SIRH5" ENSG00000134590 "Retrotransposon Gag like 8C" A6ZKI3 X 135032355-135033546 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 225.2;Esophageal apical cells: 250.4;Esophageal suprabasal cells: 271.8;Hepatic stellate cells: 225.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Lung - Smooth muscle cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 35: Non-specific - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 97: Non-specific - Cellular respiration" 13 "unprognostic (2.84e-2)" "potential prognostic unfavorable (9.45e-6)" "unprognostic (2.15e-2)" "unprognostic (8.32e-3)" "unprognostic (1.00e-1)" "unprognostic (8.49e-2)" "unprognostic (1.94e-1)" "unprognostic (1.58e-2)" "unprognostic (3.19e-1)" "unprognostic (1.73e-1)" "unprognostic (2.25e-3)" "unprognostic (1.20e-1)" "potential prognostic unfavorable (9.97e-5)" "unprognostic (8.41e-2)" "unprognostic (5.14e-3)" "unprognostic (2.81e-1)" "unprognostic (1.07e-1)" "unprognostic (1.23e-2)" "unprognostic (1.56e-2)" "unprognostic (5.17e-3)" "unprognostic (2.19e-1)" "unprognostic (1.04e-1)" "unprognostic (3.04e-2)" "unprognostic (2.55e-3)" "unprognostic (1.69e-1)" "unprognostic (9.61e-3)" "unprognostic (7.77e-2)" "unprognostic (9.92e-3)" "unprognostic (1.75e-2)" RTL9 "KIAA1318, Mar9, Mart9, RGAG1, SIRH10" ENSG00000243978 "Retrotransposon Gag like 9" Q8NET4 X 110358848-110456334 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 7.5" "Cell type enriched" "Detected in some" 4 "Sertoli cells: 225.7" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 47.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 12 "Rhabdoid: 18.5" "Adipose subcutaneous - Adipocytes (Subcutaneous), Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA001242 Enhanced NA NA "Cluster 67: Testis - Mixed function" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 3: Rhabdoid - Membrane components" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 3 "HPA001242: " "potential prognostic favorable (2.13e-4)" RTN1 NSP ENSG00000139970 "Reticulon 1" Q16799 14 59595976-59870776 "Plasma proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 444.9" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 691.7;Brain inhibitory neurons: 562.5;cDC: 747.5;Cone photoreceptor cells: 511.3;Corticotrophs: 435.9;Ependymal cells: 340.8;Gonadotrophs: 334.7;Lactotrophs: 578.3;Megakaryocyte progenitors: 355.7;Other brain neurons: 722.2;Pancreatic islet cells: 324.7;Pituitary stem cells: 306.9;Retinal horizontal cells: 364.6;Somatotrophs: 344.5;Thyrotrophs: 378.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 49.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 2.2;intermediate monocyte: 2.4;myeloid DC: 3.9" "Group enriched" "Detected in many" 15 "dendritic cells: 3.9;monocytes: 2.4" "Cancer enriched" "Detected in many" 7 "Neuroblastoma: 89.0" "Adipose visceral - Adipocytes (Visceral), Colon - Colon enteroendocrine cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002745, HPA040945, HPA044249" Enhanced Supported "Nuclear bodies,Endoplasmic reticulum" NA NA 58000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 27: Cerebellum - Synaptic function" "Cluster 14: Neurons - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 98: Neurons - Neurotransmission & signaling" 10 "Endoplasmic reticulum" "Nuclear bodies" "CAB002745: , HPA040945: , HPA044249: " "unprognostic (2.40e-2)" "unprognostic (9.43e-2)" "unprognostic (6.76e-2)" "unprognostic (1.32e-1)" "unprognostic (2.89e-2)" "unprognostic (2.21e-2)" "unprognostic (1.19e-2)" "unprognostic (4.32e-2)" "potential prognostic favorable (5.63e-6)" "unprognostic (6.72e-2)" "unprognostic (2.57e-1)" "unprognostic (6.04e-2)" "unprognostic (3.11e-3)" "unprognostic (2.29e-2)" "unprognostic (9.79e-2)" "unprognostic (1.19e-1)" "unprognostic (7.35e-2)" "unprognostic (1.06e-1)" "potential prognostic favorable (5.51e-4)" "unprognostic (7.92e-2)" "unprognostic (8.14e-2)" "unprognostic (2.98e-2)" "unprognostic (1.38e-1)" "unprognostic (5.40e-2)" "unprognostic (5.77e-1)" "unprognostic (6.06e-3)" "unprognostic (1.67e-1)" RTN2 "NSP2, NSPL1, SPG12" ENSG00000125744 "Reticulon 2" O75298 19 45485294-45497055 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "skeletal muscle: 477.7;tongue: 194.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 166.8;Extravillous trophoblasts: 217.6;Migrating cytotrophoblasts: 125.8;Myonuclei: 107.4;Platelets: 139.3;Syncytiotrophoblasts: 138.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 6.2;eosinophil: 2.6;plasmacytoid DC: 1.6" "Group enriched" "Detected in many" 10 "dendritic cells: 1.6;granulocytes: 6.2" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Pituitary gland - Lactotropes, Skeletal muscle - Skeletal myocytes, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034948, HPA078531" Approved Uncertain Vesicles NA NA "Cluster 41: Basophils - Unknown function" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 7 Vesicles "HPA034948: , HPA078531: " "unprognostic (2.94e-1)" "unprognostic (2.82e-1)" "unprognostic (1.71e-1)" "unprognostic (2.51e-1)" "unprognostic (1.17e-2)" "unprognostic (8.63e-2)" "potential prognostic unfavorable (9.40e-4)" "unprognostic (5.23e-3)" "unprognostic (2.69e-2)" "unprognostic (1.76e-1)" "unprognostic (5.70e-3)" "unprognostic (2.44e-1)" "unprognostic (1.27e-1)" "unprognostic (1.34e-2)" "unprognostic (2.41e-1)" "unprognostic (5.03e-2)" "unprognostic (1.32e-2)" "unprognostic (1.21e-1)" "unprognostic (2.13e-2)" "unprognostic (8.82e-3)" "unprognostic (5.90e-3)" "unprognostic (8.24e-3)" "unprognostic (3.94e-2)" "unprognostic (1.17e-1)" "unprognostic (4.67e-1)" "unprognostic (2.94e-1)" "unprognostic (3.10e-1)" "unprognostic (1.40e-1)" "unprognostic (2.99e-1)" "unprognostic (1.48e-1)" "unprognostic (1.05e-2)" RTN3 "ASYIP, HAP, NSPL2, NSPLII, RTN3-A1" ENSG00000133318 "Reticulon 3" O95197 11 63681446-63759891 "Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, ER-Golgi transport, Host-virus interaction, Stress response, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 620.3" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 1342.1;Neutrophils: 1878.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1079.4" "Group enriched" "Detected in all" 6 "granulocytes: 1079.4;monocytes: 400.6" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Spleen - Neutrophils_2, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015649, HPA015650" Enhanced Supported "Endoplasmic reticulum" NA NA 41000 "Cluster 21: Neutrophils - Unknown function" "Cluster 73: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 24: Non-specific - Unknown function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 51 "Endoplasmic reticulum" "HPA015649: , HPA015650: " "unprognostic (2.03e-1)" "potential prognostic unfavorable (6.44e-5)" "unprognostic (4.25e-2)" "unprognostic (9.40e-2)" "unprognostic (1.37e-1)" "unprognostic (7.55e-3)" "unprognostic (1.24e-1)" "unprognostic (3.24e-2)" "unprognostic (1.46e-2)" "unprognostic (6.16e-3)" "potential prognostic favorable (3.10e-5)" "unprognostic (1.12e-1)" "unprognostic (3.77e-2)" "validated prognostic unfavorable (6.96e-9)" "validated prognostic unfavorable (1.52e-4)" "unprognostic (2.47e-3)" "unprognostic (1.22e-1)" "unprognostic (8.51e-2)" "unprognostic (8.24e-2)" "unprognostic (1.37e-2)" "unprognostic (1.92e-1)" "unprognostic (2.00e-3)" "unprognostic (8.57e-2)" "unprognostic (7.04e-2)" "unprognostic (1.27e-1)" "unprognostic (1.10e-1)" "unprognostic (4.13e-1)" "unprognostic (1.11e-1)" "unprognostic (1.14e-2)" "unprognostic (3.48e-2)" "unprognostic (4.00e-2)" RTN4 "ASY, KIAA0886, NOGO, NSP-CL" ENSG00000115310 "Reticulon 4" Q9NQC3 2 54972187-55112621 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Neurogenesis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Müller glia: 3824.3;Neutrophils: 2066.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 97.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Liver - Hepatocytes, Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005388, HPA023977" Supported Enhanced "Endoplasmic reticulum" NA NA 2600000 "Cluster 45: Eosinophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 11: Muller glia cells - Retinal homeostasis" 147 "Endoplasmic reticulum" "CAB005388: , HPA023977: " "unprognostic (1.90e-1)" "unprognostic (1.65e-3)" "unprognostic (2.22e-1)" "unprognostic (6.23e-3)" "unprognostic (2.55e-1)" "unprognostic (2.13e-1)" "potential prognostic unfavorable (5.02e-4)" "unprognostic (1.43e-2)" "potential prognostic unfavorable (7.30e-5)" "unprognostic (8.81e-2)" "potential prognostic favorable (1.22e-5)" "unprognostic (2.09e-1)" "unprognostic (5.12e-2)" "unprognostic (6.92e-2)" "unprognostic (3.67e-1)" "unprognostic (3.60e-3)" "unprognostic (1.80e-1)" "unprognostic (4.41e-2)" "unprognostic (6.46e-2)" "unprognostic (1.91e-1)" "unprognostic (1.55e-2)" "unprognostic (9.66e-3)" "unprognostic (3.76e-2)" "unprognostic (3.07e-1)" "unprognostic (3.35e-1)" "unprognostic (1.37e-1)" "unprognostic (1.30e-1)" "unprognostic (2.76e-2)" "unprognostic (1.67e-1)" "unprognostic (2.63e-1)" "unprognostic (1.50e-1)" RTN4IP1 NIMP ENSG00000130347 "Reticulon 4 interacting protein 1" Q8WWV3 6 106570771-106629498 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Neurogenesis, Ubiquinone biosynthesis" Oxidoreductase "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 73.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "breast cancer: 45.5" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036357 Approved NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cellular respiration" "Cluster 31: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 55: Myocytes - Oxidative muscle function" 20 "HPA036357: " "unprognostic (1.24e-2)" "potential prognostic unfavorable (8.33e-5)" "unprognostic (2.24e-1)" "unprognostic (4.67e-2)" "unprognostic (1.18e-1)" "unprognostic (1.87e-3)" "unprognostic (2.50e-1)" "unprognostic (7.54e-2)" "unprognostic (4.04e-2)" "unprognostic (2.89e-1)" "unprognostic (2.64e-3)" "unprognostic (2.56e-2)" "potential prognostic favorable (3.39e-5)" "unprognostic (1.14e-3)" "unprognostic (1.34e-3)" "unprognostic (6.11e-2)" "unprognostic (1.52e-1)" "unprognostic (4.39e-2)" "unprognostic (2.41e-1)" "unprognostic (2.11e-1)" "unprognostic (5.47e-2)" "unprognostic (1.07e-1)" "unprognostic (2.74e-1)" "unprognostic (6.77e-2)" "unprognostic (4.64e-3)" "unprognostic (2.97e-2)" "unprognostic (8.96e-2)" "unprognostic (2.04e-1)" "unprognostic (2.90e-1)" "unprognostic (1.01e-1)" "unprognostic (5.56e-2)" RTN4R NOGOR ENSG00000040608 "Reticulon 4 receptor" Q9BZR6 22 20241415-20283246 "Disease related genes, Human disease related genes, Predicted membrane proteins" Receptor "Disease variant, Schizophrenia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 82.6" "Cell type enhanced" "Detected in many" "Bergmann glia: 9.9;Brain excitatory neurons: 26.2;Extravillous trophoblasts: 13.0;Müller glia: 11.3;Respiratory deuterosomal cells: 11.4;Retinal bipolar cells: 10.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 10.8" "Lineage enriched" "Detected in many" 9 "T-cells: 10.8" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Skeletal muscle - Fibroblasts, Skin - Keratinocyte (other), Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB012443 Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA 780000 "Cluster 11: T-cells - Unknown function" "Cluster 27: Cerebellum - Synaptic function" "Cluster 34: Non-specific - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 18 "Plasma membrane, Focal adhesion sites" "Actin filaments" "CAB012443: " "unprognostic (1.40e-1)" "unprognostic (2.35e-1)" "unprognostic (3.69e-1)" "unprognostic (2.58e-3)" "unprognostic (2.59e-1)" "unprognostic (1.94e-2)" "unprognostic (7.66e-2)" "unprognostic (1.01e-2)" "unprognostic (1.14e-1)" "unprognostic (1.24e-3)" "unprognostic (6.72e-2)" "unprognostic (1.05e-1)" "unprognostic (2.61e-1)" "unprognostic (7.10e-2)" "unprognostic (1.03e-1)" "unprognostic (2.37e-1)" "unprognostic (1.45e-2)" "unprognostic (1.73e-1)" "unprognostic (9.35e-3)" "unprognostic (9.43e-2)" "unprognostic (7.04e-2)" "unprognostic (3.01e-1)" "unprognostic (4.18e-2)" "unprognostic (1.57e-1)" "unprognostic (1.68e-3)" "unprognostic (1.23e-1)" "unprognostic (1.25e-1)" "unprognostic (1.34e-1)" RTN4RL1 "DKFZp547J144, NgR3, NGRH2" ENSG00000185924 "Reticulon 4 receptor like 1" Q86UN2 17 1934677-2025334 "Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.8" "Group enriched" "Detected in many" 5 "Early spermatids: 432.8;Late spermatids: 1254.8" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 12.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 8.7" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044428 Uncertain Approved "Nucleoplasm,Plasma membrane,Actin filaments,Midbody" "Intracellular and membrane" Receptor Yes NA 19000 "Cluster 2: Non-specific - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 5 "Actin filaments" "Nucleoplasm, Plasma membrane, Midbody" "HPA044428: " "unprognostic (8.26e-2)" "unprognostic (1.24e-1)" "unprognostic (3.56e-1)" "unprognostic (6.15e-3)" "unprognostic (3.66e-2)" "unprognostic (2.37e-2)" "unprognostic (7.65e-2)" "unprognostic (1.82e-1)" "unprognostic (2.30e-3)" "unprognostic (6.08e-3)" "unprognostic (1.89e-2)" "unprognostic (4.11e-2)" "unprognostic (3.49e-2)" "unprognostic (1.80e-3)" "unprognostic (7.04e-3)" "unprognostic (5.20e-2)" "unprognostic (3.01e-2)" "unprognostic (4.20e-2)" "unprognostic (2.11e-2)" RTN4RL2 "NgR2, NGRH1" ENSG00000186907 "Reticulon 4 receptor like 2" Q86UN3 11 57460528-57477534 "Plasma proteins, Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "brain: 34.0;liver: 37.8;thyroid gland: 28.5" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 14.8;Extravillous trophoblasts: 11.6;Hepatocytes: 19.3;Late primary spermatocytes: 19.3;Melanocytes: 8.0;Oligodendrocyte progenitor cells: 11.8;Pancreatic islet cells: 8.9;Pericytes: 8.1;Retinal bipolar cells: 24.9" "Cell type enhanced" "Detected in many" "deep-layer intratelencephalic: 52.0" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in all" 10 "amygdala: 72.3;basal ganglia: 61.2;cerebral cortex: 116.1;hippocampal formation: 86.0;white matter: 49.6" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Pituitary gland - Corticotropes, Spleen - Fibroblasts_1" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 9 "amygdala: 25.0;cerebral cortex: 45.0;hippocampal formation: 38.9" "Intracellular and membrane" Receptor NA NA 12000000 "Cluster 36: Brain & Liver - Signaling" "Cluster 51: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 35: Neurons - Synaptic function & neurogenesis" 1 "unprognostic (1.00e-1)" "unprognostic (2.06e-3)" "unprognostic (1.00e-1)" "unprognostic (8.87e-2)" "unprognostic (5.69e-2)" "unprognostic (3.42e-3)" "unprognostic (1.18e-1)" "unprognostic (1.53e-2)" "unprognostic (1.45e-1)" "unprognostic (1.20e-2)" "unprognostic (4.84e-2)" "unprognostic (7.55e-2)" "unprognostic (1.61e-2)" "unprognostic (4.36e-2)" "unprognostic (1.16e-1)" "unprognostic (5.71e-2)" "unprognostic (1.17e-1)" "unprognostic (2.44e-1)" "unprognostic (1.61e-1)" "unprognostic (5.78e-2)" "unprognostic (2.77e-1)" "unprognostic (2.80e-2)" "unprognostic (2.38e-1)" "unprognostic (1.18e-1)" "unprognostic (9.22e-2)" "unprognostic (9.97e-2)" "unprognostic (1.39e-2)" "unprognostic (1.41e-2)" "unprognostic (6.52e-3)" "unprognostic (2.23e-1)" RTP1 "MGC35450, Z3CXXC1" ENSG00000175077 "Receptor transporter protein 1" P59025 3 187197486-187201462 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 2.1" "Cell type enhanced" "Detected in some" "Early spermatids: 2.6;Late primary spermatocytes: 7.8;Late spermatids: 2.7;Oocytes: 27.6;Other brain neurons: 4.5" "Cell type enhanced" "Detected in some" "hippocampal CA4: 5.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 26 "Rhabdoid: 1.3;testis cancer: 3.7" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 3: Rhabdoid - Membrane components" "Cluster 41: Oocytes - Oogenesis" "unprognostic (4.10e-2)" RTP2 "MGC78665, Z3CXXC2" ENSG00000198471 "Receptor transporter protein 2" Q5QGT7 3 187698259-187702557 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 16 "skeletal muscle: 1.9;testis: 1.1" "Cell type enhanced" "Detected in some" "Early spermatids: 9.8;Epididymal clear cells: 2.0;Late primary spermatocytes: 15.8;Late spermatids: 3.6" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 11 "Kidney Chromophobe (TCGA): 3.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Breast cancer - Unknown function" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" 65 "unprognostic (1.16e-1)" RTP3 "LTM1, TMEM7, Z3CXXC3" ENSG00000163825 "Receptor transporter protein 3" Q9BQQ7 3 46494611-46500950 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 44 "liver: 111.0" "Cell type enriched" "Detected in some" 26 "Hepatocytes: 104.0" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Liver Hepatocellular Carcinoma (TCGA): 52.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "head and neck cancer: 3.7" "Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA075932 Uncertain Mitochondria NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 93: Hepatocytes - Bile production & excretion" Mitochondria "HPA075932: " "unprognostic (1.35e-1)" "unprognostic (9.34e-2)" "validated prognostic favorable (8.70e-6)" "validated prognostic favorable (2.10e-4)" "unprognostic (2.03e-1)" "unprognostic (1.92e-1)" RTP4 "IFRG28, Z3CXXC4" ENSG00000136514 "Receptor transporter protein 4" Q96DX8 3 187368385-187372076 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Epididymal basal cells: 46.1;Epididymal clear cells: 36.7;Epididymal efferent duct absorptive cells: 31.2;Epididymal efferent duct ciliated cells: 64.2" "Cell type enhanced" "Detected in some" "endothelial cell: 11.5;fibroblast: 6.9;leukocyte: 5.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "head and neck cancer: 11.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064887, HPA071189" Uncertain Supported Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 5 Nucleoplasm "HPA064887: , HPA071189: " "unprognostic (2.09e-3)" "unprognostic (2.33e-2)" "unprognostic (1.17e-1)" "unprognostic (1.62e-1)" "unprognostic (2.05e-1)" "unprognostic (1.43e-1)" "unprognostic (1.57e-1)" "unprognostic (4.96e-1)" "unprognostic (4.29e-1)" "unprognostic (2.29e-1)" "unprognostic (1.04e-2)" "unprognostic (2.84e-3)" "unprognostic (5.55e-2)" "unprognostic (5.60e-2)" "potential prognostic favorable (3.88e-4)" "unprognostic (1.78e-1)" "unprognostic (2.46e-1)" "unprognostic (3.76e-2)" "unprognostic (9.03e-2)" "unprognostic (2.99e-1)" "unprognostic (5.87e-2)" "unprognostic (3.61e-3)" "unprognostic (2.33e-1)" "unprognostic (9.63e-2)" "unprognostic (1.25e-1)" "unprognostic (8.75e-2)" "unprognostic (1.25e-1)" "unprognostic (7.00e-2)" "unprognostic (7.66e-3)" "potential prognostic favorable (3.63e-4)" "unprognostic (1.54e-1)" RTP5 "C2orf85, CXXC11, FLJ33590, Z3CXXC5" ENSG00000188011 "Receptor transporter protein 5 (putative)" Q14D33 2 241869600-241873823 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 35 "brain: 49.6" "Group enriched" "Detected in some" 13 "Brain excitatory neurons: 7.0;Brain inhibitory neurons: 8.6;Oligodendrocyte progenitor cells: 27.1;Other brain neurons: 19.2" "Cell type enhanced" "Detected in many" "thalamic excitatory: 26.0" "Cancer enriched" "Detected in single" 12 "Glioblastoma Multiforme (TCGA): 1.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - T-cells, Prostate - T-cells" "Low region specificity" "Detected in all" HPA050902 Enhanced NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 29: Forebrain - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 98: Neurons - Neurotransmission & signaling" 49 "HPA050902: " "unprognostic (4.09e-1)" "potential prognostic favorable (3.21e-4)" RTRAF "C14orf166, CGI-99, CLE, CLE7, hCLE1, LCRP369, RLLM1" ENSG00000087302 "RNA transcription, translation and transport factor" Q9Y224 14 51989514-52010694 "Essential proteins, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 598.2;Late primary spermatocytes: 1026.9;Late spermatids: 825.2;Oocytes: 842.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039824 Supported Supported Nucleoplasm NA NA 15000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 15: Non-specific - Protein processing" 43 Nucleoplasm "HPA039824: " "unprognostic (1.09e-2)" "unprognostic (1.42e-1)" "unprognostic (2.67e-1)" "unprognostic (1.25e-2)" "unprognostic (1.92e-2)" "unprognostic (2.54e-1)" "unprognostic (2.86e-2)" "unprognostic (2.74e-3)" "unprognostic (2.59e-3)" "unprognostic (1.15e-3)" "unprognostic (1.92e-2)" "unprognostic (9.69e-2)" "potential prognostic unfavorable (1.22e-4)" "potential prognostic unfavorable (5.76e-4)" "unprognostic (2.28e-2)" "unprognostic (1.36e-2)" "unprognostic (4.44e-2)" "unprognostic (7.97e-2)" "unprognostic (1.44e-1)" "unprognostic (7.54e-2)" "unprognostic (1.28e-1)" "unprognostic (1.35e-1)" "unprognostic (1.27e-1)" "unprognostic (2.48e-2)" "unprognostic (1.13e-1)" "unprognostic (5.94e-2)" "unprognostic (9.66e-2)" "unprognostic (3.63e-1)" "unprognostic (2.84e-2)" RTTN DKFZP434G145 ENSG00000176225 Rotatin Q86VV8 18 70003031-70205726 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Microglia: 746.1" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 849.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA041343, HPA041967, HPA075089" Uncertain Uncertain "Centrosome,Basal body,Cytosol" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 1 Cytosol "Centrosome, Basal body" "HPA041343: , HPA041967: , HPA075089: " "unprognostic (1.36e-3)" "unprognostic (3.22e-2)" "unprognostic (1.18e-1)" "unprognostic (3.10e-2)" "unprognostic (6.67e-2)" "unprognostic (5.60e-2)" "unprognostic (1.57e-1)" "unprognostic (1.48e-3)" "unprognostic (1.47e-3)" "unprognostic (1.96e-1)" "potential prognostic favorable (5.78e-4)" "unprognostic (1.49e-1)" "unprognostic (9.81e-2)" "unprognostic (5.08e-2)" "unprognostic (4.90e-2)" "unprognostic (6.65e-3)" "unprognostic (2.23e-1)" "unprognostic (5.60e-2)" "unprognostic (1.22e-1)" "unprognostic (2.58e-1)" "unprognostic (9.41e-3)" "unprognostic (1.36e-1)" "unprognostic (1.52e-1)" "unprognostic (9.77e-2)" "unprognostic (3.56e-1)" "unprognostic (4.72e-2)" "unprognostic (1.57e-1)" "unprognostic (3.13e-1)" RUBCN "KIAA0226, rubicon, rundataxin" ENSG00000145016 "Rubicon autophagy regulator" Q92622 3 197668867-197749727 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Autophagy, Endocytosis, Immunity, Phagocytosis" Neurodegeneration "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "pDCs: 421.3;Plasma cells: 171.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050908, HPA054497" Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 19: Astrocytes - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 29 "Vesicles, Cytosol" Nucleoplasm "HPA050908: , HPA054497: " "unprognostic (1.55e-2)" "unprognostic (1.85e-2)" "unprognostic (1.15e-1)" "unprognostic (1.81e-1)" "unprognostic (9.06e-3)" "unprognostic (1.28e-1)" "unprognostic (5.47e-3)" "unprognostic (2.63e-2)" "unprognostic (1.99e-2)" "potential prognostic favorable (6.20e-4)" "unprognostic (1.58e-2)" "unprognostic (2.75e-2)" "potential prognostic unfavorable (8.24e-4)" "unprognostic (3.12e-1)" "unprognostic (2.57e-2)" "unprognostic (9.20e-2)" "unprognostic (8.19e-3)" "unprognostic (1.48e-2)" "unprognostic (1.66e-1)" "unprognostic (6.26e-2)" "unprognostic (1.67e-2)" "unprognostic (1.51e-2)" "unprognostic (1.53e-1)" "unprognostic (5.11e-3)" "unprognostic (2.06e-1)" "unprognostic (1.54e-2)" "unprognostic (3.09e-1)" "unprognostic (4.01e-1)" "unprognostic (3.97e-2)" RUBCNL "C13orf18, FLJ21562, KIAA0226L, PACER" ENSG00000102445 "Rubicon like autophagy enhancer" Q9H714 13 46334681-46438190 "Predicted intracellular proteins" "Autophagy, Lipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 38.5" "Cell type enhanced" "Detected in many" "B-cells: 295.4;Bergmann glia: 146.0;cDC: 123.8;Early spermatids: 181.7;Late spermatids: 182.0;Microglia: 239.5;Neutrophils: 847.2;pDCs: 281.7" "Group enriched" "Detected in many" 7 "Bergmann glia: 147.7;central nervous system macrophage: 318.5" "Group enriched" "Detected in many" 5 "Colon Adenocarcinoma (TCGA): 43.7;Rectum Adenocarcinoma (TCGA): 54.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 15 "memory B-cell: 161.8;naive B-cell: 156.3;neutrophil: 124.6;plasmacytoid DC: 106.4" "Group enriched" "Detected in many" 15 "B-cells: 161.8;dendritic cells: 106.4;granulocytes: 124.6" "Cancer enriched" "Detected in many" 5 "lymphoma: 144.9" "Adrenal gland - Macrophages, Breast - T-cells, Spleen - B-cells (Spleen), Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - T-cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA026614 Approved Approved Cytosol NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 4 Cytosol "HPA026614: " "potential prognostic favorable (7.11e-4)" "unprognostic (8.34e-2)" "unprognostic (4.60e-2)" "unprognostic (7.67e-2)" "potential prognostic favorable (2.30e-5)" "unprognostic (4.59e-2)" "unprognostic (1.25e-2)" "unprognostic (2.71e-3)" "unprognostic (1.73e-1)" "unprognostic (1.63e-1)" "unprognostic (2.78e-3)" "unprognostic (1.06e-3)" "unprognostic (2.83e-2)" "unprognostic (1.01e-1)" "unprognostic (6.04e-3)" "unprognostic (2.48e-2)" "unprognostic (4.32e-3)" "unprognostic (1.78e-1)" "unprognostic (3.90e-3)" "unprognostic (3.61e-1)" "unprognostic (2.51e-3)" "unprognostic (4.04e-2)" "unprognostic (1.28e-1)" "unprognostic (1.26e-1)" "unprognostic (5.38e-2)" "unprognostic (1.10e-1)" "unprognostic (1.07e-1)" RUFY1 "FLJ22251, RABIP4, ZFYVE12" ENSG00000176783 "RUN and FYVE domain containing 1" Q96T51 5 179550554-179610012 "Plasma proteins, Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Platelets: 1848.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038804 Approved Supported "Nuclear speckles,Vesicles,Cytosol" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 47: Platelets - Hemostasis" 39 "Vesicles, Cytosol" "Nuclear speckles" "HPA038804: " "unprognostic (7.21e-2)" "unprognostic (5.52e-2)" "unprognostic (5.62e-2)" "unprognostic (1.01e-1)" "unprognostic (4.14e-2)" "unprognostic (1.53e-2)" "unprognostic (7.93e-2)" "unprognostic (2.09e-2)" "unprognostic (1.54e-1)" "unprognostic (2.22e-3)" "potential prognostic favorable (7.90e-6)" "unprognostic (2.42e-2)" "unprognostic (5.61e-3)" "unprognostic (6.44e-2)" "unprognostic (8.52e-3)" "unprognostic (2.15e-1)" "unprognostic (2.78e-1)" "unprognostic (6.27e-2)" "unprognostic (5.60e-2)" "unprognostic (3.97e-1)" "unprognostic (9.96e-3)" "unprognostic (2.35e-1)" "unprognostic (2.40e-3)" "unprognostic (1.27e-1)" "unprognostic (3.34e-1)" "unprognostic (7.77e-2)" "unprognostic (6.91e-2)" "unprognostic (8.36e-2)" "unprognostic (2.77e-1)" "unprognostic (2.26e-1)" "unprognostic (2.00e-1)" RUFY2 "FLJ10063, KIAA1537, RABIP4R, ZFYVE13" ENSG00000204130 "RUN and FYVE domain containing 2" Q8WXA3 10 68341107-68407294 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 31.3" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039792 Approved Approved Nucleoplasm NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 27: Cerebellum - Synaptic function" "Cluster 30: White matter - Myelination" "Cluster 52: Non-specific - Mitochondria" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 1 Nucleoplasm "HPA039792: " "unprognostic (8.00e-2)" "unprognostic (2.97e-2)" "unprognostic (1.88e-1)" "unprognostic (3.56e-1)" "unprognostic (2.08e-1)" "unprognostic (1.98e-2)" "unprognostic (3.04e-2)" "potential prognostic favorable (9.15e-4)" "unprognostic (2.71e-1)" "unprognostic (1.19e-2)" "potential prognostic favorable (2.72e-5)" "unprognostic (1.56e-2)" "unprognostic (4.16e-1)" "unprognostic (2.96e-2)" "unprognostic (1.41e-1)" "unprognostic (1.98e-1)" "unprognostic (4.70e-2)" "unprognostic (5.92e-2)" "unprognostic (9.07e-2)" "unprognostic (2.63e-1)" "unprognostic (1.18e-1)" "unprognostic (1.70e-1)" "unprognostic (2.57e-3)" "unprognostic (7.99e-2)" "unprognostic (5.10e-2)" "unprognostic (6.45e-2)" "unprognostic (1.12e-1)" "unprognostic (2.60e-1)" "unprognostic (2.96e-1)" "unprognostic (9.76e-3)" "unprognostic (1.01e-1)" RUFY3 "KIAA0871, RIPx, Singar1, ZFYVE30" ENSG00000018189 "RUN and FYVE domain containing 3" Q7L099 4 70704204-70808619 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" Oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 111.4" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 842.9;Sertoli cells: 922.5;Somatotrophs: 673.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022952, HPA022970" Enhanced Supported Cytosol NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 18: Adrenal cortex cells - Steroidogensis" 5 Cytosol "HPA022952: , HPA022970: " "unprognostic (1.13e-1)" "unprognostic (1.29e-2)" "unprognostic (1.94e-1)" "unprognostic (5.52e-3)" "unprognostic (9.33e-2)" "unprognostic (2.25e-1)" "unprognostic (2.34e-1)" "unprognostic (1.03e-3)" "potential prognostic favorable (9.63e-5)" "unprognostic (2.69e-3)" "unprognostic (1.04e-1)" "unprognostic (9.20e-2)" "unprognostic (1.47e-1)" "potential prognostic unfavorable (3.87e-4)" "unprognostic (2.69e-2)" "unprognostic (1.23e-2)" "unprognostic (1.64e-1)" "unprognostic (7.37e-2)" "unprognostic (2.49e-2)" "unprognostic (1.13e-1)" "unprognostic (2.97e-2)" "unprognostic (2.48e-3)" "unprognostic (8.69e-3)" "unprognostic (2.19e-1)" "unprognostic (1.03e-1)" "unprognostic (2.82e-2)" "unprognostic (1.07e-1)" "unprognostic (1.27e-1)" "unprognostic (4.55e-2)" "unprognostic (1.41e-1)" "unprognostic (4.27e-2)" RUFY4 "FLJ46536, ZFYVE31" ENSG00000188282 "RUN and FYVE domain containing 4" Q6ZNE9 2 218034960-218090584 "Predicted intracellular proteins" Autophagy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 2.1" "Cell type enhanced" "Detected in some" "cDC: 6.4;Kupffer cells: 32.8;Macrophages: 7.0;Megakaryocytes: 12.4;Monocyte progenitors: 7.3;monocytes: 6.3;Oligodendrocyte progenitor cells: 15.5;pDCs: 9.2;Platelets: 9.8;Prostatic hillock cells: 7.9" "Group enriched" "Detected in some" 5 "hippocampal CA1-3: 8.0;oligodendrocyte precursor cell: 18.7" "Low cancer specificity" "Detected in some" "Group enriched" "Detected in some" 5 "cerebral cortex: 2.9;hippocampal formation: 1.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA037980 Uncertain NA NA "Cluster 66: Lymphoid tissue - Immune response" "Cluster 29: Forebrain - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 21 "HPA037980: " "unprognostic (9.92e-3)" "unprognostic (1.52e-3)" "unprognostic (1.29e-1)" "unprognostic (1.29e-1)" "unprognostic (2.65e-1)" "unprognostic (5.03e-3)" "unprognostic (8.77e-2)" RUNDC1 DKFZp761H0421 ENSG00000198863 "RUN domain containing 1" Q96C34 17 42980565-42995142 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 99.9;Fallopian tube ciliated cells: 70.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023726 Uncertain Approved "Nuclear speckles,Cytosol" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 22: Epididymis - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" "Nuclear speckles" Cytosol "HPA023726: " "unprognostic (3.79e-2)" "unprognostic (3.37e-1)" "unprognostic (2.08e-1)" "unprognostic (2.51e-2)" "unprognostic (4.14e-2)" "unprognostic (1.60e-1)" "unprognostic (1.19e-1)" "unprognostic (3.49e-1)" "unprognostic (2.25e-1)" "unprognostic (1.08e-3)" "potential prognostic favorable (1.01e-4)" "unprognostic (2.35e-3)" "unprognostic (5.52e-2)" "unprognostic (4.89e-2)" "unprognostic (5.44e-3)" "unprognostic (2.01e-1)" "unprognostic (1.54e-1)" "unprognostic (2.25e-1)" "unprognostic (9.68e-3)" "unprognostic (7.57e-2)" "unprognostic (6.57e-3)" "unprognostic (3.13e-3)" "unprognostic (1.88e-1)" "unprognostic (1.87e-1)" "unprognostic (1.07e-2)" "unprognostic (2.51e-1)" "unprognostic (9.48e-2)" "unprognostic (7.00e-2)" "unprognostic (2.06e-1)" "unprognostic (1.46e-1)" "unprognostic (7.33e-2)" RUNDC3A "RAP2IP, RPIP8" ENSG00000108309 "RUN domain containing 3A" Q59EK9 17 44308413-44318670 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 297.6;pituitary gland: 94.7" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 31.9;Brain excitatory neurons: 62.5;Brain inhibitory neurons: 42.7;Corticotrophs: 33.6;Early spermatids: 27.4;Erythrocytes: 49.1;Gonadotrophs: 26.8;Lactotrophs: 26.1;Late spermatids: 150.0;Neuroendocrine cells: 29.8;Other brain neurons: 47.9;Pancreatic islet cells: 33.1;Retinal amacrine cells: 24.9;Retinal bipolar cells: 29.5;Somatotrophs: 33.0;Thyrotrophs: 23.0" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Glioblastoma Multiforme (TCGA): 28.8;Pancreatic Adenocarcinoma (TCGA): 10.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "lung cancer: 12.2;Neuroblastoma: 48.1" "Adrenal gland - Adrenal medulla cells, Pancreas - Alpha cells, Skin - Keratinocyte (granular), Spleen - Erythrocytes, Stomach - Gastric enteroendocrine cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023548, HPA070733" Enhanced Supported Enhanced Vesicles NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" 24 Vesicles "HPA023548: , HPA070733: " "unprognostic (1.86e-1)" "unprognostic (6.14e-2)" "unprognostic (3.99e-2)" "unprognostic (7.61e-2)" "unprognostic (2.24e-1)" "unprognostic (2.84e-1)" "potential prognostic favorable (6.97e-4)" "unprognostic (6.98e-2)" "unprognostic (1.53e-2)" "unprognostic (3.53e-3)" "unprognostic (4.85e-2)" "unprognostic (9.11e-2)" "unprognostic (1.91e-1)" "unprognostic (3.58e-2)" "unprognostic (1.01e-1)" "unprognostic (5.73e-3)" "unprognostic (6.47e-2)" "potential prognostic favorable (5.27e-4)" "unprognostic (2.06e-3)" "unprognostic (1.70e-1)" "unprognostic (9.64e-3)" "unprognostic (1.23e-1)" "unprognostic (2.16e-1)" "unprognostic (2.13e-2)" RUNDC3B "RPIB9, RPIP9" ENSG00000105784 "RUN domain containing 3B" Q96NL0 7 87627548-87832296 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 7.8;brain: 5.0;liver: 5.6" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 376.3;Brain excitatory neurons: 205.9;Brain inhibitory neurons: 228.1;Enterocytes: 88.5;Gonadotrophs: 110.9;Hematopoietic stem cells: 165.9;Other brain neurons: 188.1;Retinal amacrine cells: 97.6;Retinal ganglion cells: 220.2;Vascular endothelial cells: 145.9" "Cell type enhanced" "Detected in all" "endothelial cell: 991.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Neuroblastoma: 1.8" "Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Endothelial cells, Stomach - Endothelial cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056968, HPA057155" Uncertain Approved "Intermediate filaments,Cytokinetic bridge,Primary cilium,Centrosome,Basal body,Cytosol" Yes NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 1: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 104: Brain endothelial cells - Blood brain barrier" 4 "Intermediate filaments" "Cytokinetic bridge, Primary cilium, Centrosome, Basal body, Cytosol" "HPA056968: , HPA057155: " "unprognostic (1.38e-1)" "unprognostic (9.04e-2)" "potential prognostic favorable (9.71e-4)" "potential prognostic favorable (9.17e-6)" RUNX1 "AML1, AMLCR1, CBFA2, PEBP2A2" ENSG00000159216 "RUNX family transcription factor 1" Q01196 21 34787801-36004667 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 42.9" "Cell type enhanced" "Detected in many" "Hematopoietic stem cells: 1602.7;Megakaryocyte progenitors: 1572.8;Megakaryocyte-Erythroid progenitors: 1466.1;Neutrophil progenitors: 1514.5;Salivary basal cells: 1411.7;Salivary duct cells: 1811.7" "Group enriched" "Detected in all" 14 "central nervous system macrophage: 1198.3;leukocyte: 976.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 24.0" "Lineage enriched" "Detected in all" 5 "granulocytes: 24.0" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Minor salivary glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA004176, HPA037912" Enhanced Enhanced Nucleoplasm,Vesicles No No "Cluster 22: Eosinophils - Transcription" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 6: Leukemia - Signal transduction" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 58 Nucleoplasm Vesicles "HPA004176: , HPA037912: " "unprognostic (1.32e-3)" "unprognostic (1.35e-2)" "unprognostic (2.33e-1)" "unprognostic (5.10e-3)" "unprognostic (2.52e-2)" "unprognostic (1.19e-2)" "unprognostic (1.39e-2)" "unprognostic (1.30e-2)" "unprognostic (2.70e-2)" "unprognostic (2.53e-2)" "potential prognostic unfavorable (7.51e-8)" "unprognostic (8.32e-3)" "unprognostic (3.61e-2)" "unprognostic (1.32e-1)" "unprognostic (1.52e-1)" "unprognostic (9.48e-2)" "potential prognostic unfavorable (1.69e-4)" "unprognostic (3.58e-1)" "unprognostic (1.57e-1)" "unprognostic (4.75e-3)" "unprognostic (1.70e-2)" "unprognostic (1.18e-2)" "unprognostic (2.32e-2)" "unprognostic (7.78e-2)" "unprognostic (2.64e-1)" "unprognostic (2.39e-2)" "unprognostic (9.91e-2)" "unprognostic (8.50e-2)" "unprognostic (3.67e-1)" "unprognostic (6.66e-2)" "unprognostic (1.54e-1)" RUNX1T1 "AML1T1, CBFA2T1, CDR, ETO, MTG8, ZMYND2" ENSG00000079102 "RUNX1 partner transcriptional co-repressor 1" Q06455 8 91954972-92103286 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.6" "Cell type enhanced" "Detected in many" "Bergmann glia: 370.7;Brain excitatory neurons: 516.2;Brain inhibitory neurons: 304.0;Corticotrophs: 448.9;Fibro-adipogenic progenitors: 910.6;Lactotrophs: 419.6;Leydig cells: 387.0;Oligodendrocyte progenitor cells: 350.8;Peritubular myoid cells: 328.3;Retinal amacrine cells: 325.9;Retinal bipolar cells: 374.8;Sertoli cells: 311.4;Thyrotrophs: 346.2;Vascular endothelial cells: 306.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 11.6;testis cancer: 7.7" "Breast - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049852, HPA070951" Approved Supported Nucleoplasm NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 35: Non-specific - DNA binding" "Cluster 37: Non-specific - mRNA processing" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 27 Nucleoplasm "HPA049852: , HPA070951: " "unprognostic (1.02e-1)" "unprognostic (3.06e-1)" "unprognostic (6.07e-2)" "unprognostic (1.22e-1)" "unprognostic (9.40e-2)" "validated prognostic favorable (3.28e-5)" "validated prognostic favorable (4.43e-5)" "unprognostic (2.61e-3)" "unprognostic (3.56e-2)" "unprognostic (1.58e-1)" "unprognostic (5.33e-3)" "unprognostic (7.06e-2)" "unprognostic (2.95e-1)" "unprognostic (1.62e-2)" "unprognostic (1.04e-2)" "unprognostic (1.88e-1)" RUNX2 "AML3, CBFA1, CCD, CCD1, PEBP2A1, PEBP2aA1" ENSG00000124813 "RUNX family transcription factor 2" Q13950 6 45328157-45664349 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" DNA-binding "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 374.3;Innate lymphoid cells: 924.4;Late spermatids: 390.5;Microglia: 449.9;pDCs: 868.3;Salivary duct cells: 518.3;Salivary ionocytes: 723.4;Thymocytes: 695.3" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 573.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 22.2" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Myeloma: 29.5" "Skin - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB008374, HPA022040, CAB062561, CAB068226, HPA070715" Enhanced Enhanced Nucleoplasm No No "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 72: Neuronal - Signal transduction" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 32 Nucleoplasm "CAB008374: , CAB062561: , CAB068226: , HPA022040: , HPA070715: " "unprognostic (2.74e-1)" "unprognostic (9.56e-2)" "unprognostic (1.02e-1)" "unprognostic (1.09e-1)" "unprognostic (1.34e-2)" "unprognostic (4.25e-2)" "unprognostic (3.54e-2)" "unprognostic (2.60e-1)" "unprognostic (4.92e-2)" "potential prognostic unfavorable (3.38e-4)" "validated prognostic unfavorable (6.17e-5)" "validated prognostic unfavorable (1.61e-4)" "unprognostic (2.52e-1)" "unprognostic (4.06e-2)" "unprognostic (1.58e-2)" "unprognostic (4.06e-2)" "unprognostic (1.04e-1)" "unprognostic (2.96e-2)" "unprognostic (1.46e-2)" "unprognostic (4.10e-3)" "unprognostic (1.58e-2)" "unprognostic (1.39e-1)" "unprognostic (1.96e-1)" "unprognostic (3.81e-3)" "unprognostic (2.36e-1)" "unprognostic (2.89e-1)" "unprognostic (3.76e-3)" "unprognostic (3.29e-2)" "unprognostic (9.05e-2)" "unprognostic (3.84e-2)" RUNX3 "AML2, CBFA3, PEBP2A3" ENSG00000020633 "RUNX family transcription factor 3" Q13761 1 24899511-24965121 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 66.3;lymphoid tissue: 33.3" "Cell type enhanced" "Detected in many" "B-cells: 122.9;cDC: 179.1;Innate lymphoid cells: 271.8;Macrophages: 96.9;Mast cells: 81.1;Melanocytes: 109.5;monocytes: 77.0;NK-cells: 582.8;T-cells: 517.6;Thymocytes: 107.6" "Cell type enriched" "Detected in some" 17 "leukocyte: 360.7" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 44.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "lymphoma: 49.5;Myeloma: 38.2" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Heart muscle - T-cells, Prostate - T-cells, Skin - Eccrine sweat gland cells, Testis - Spermatogonia, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA004195, CAB025416, HPA059006" Enhanced Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 24 "Nucleoplasm, Vesicles" Cytosol "CAB025416: , HPA004195: , HPA059006: " "unprognostic (5.93e-2)" "unprognostic (8.48e-3)" "unprognostic (5.93e-3)" "unprognostic (5.56e-1)" "potential prognostic unfavorable (8.07e-4)" "unprognostic (4.87e-2)" "unprognostic (6.74e-2)" "unprognostic (9.55e-2)" "unprognostic (2.51e-1)" "unprognostic (2.67e-2)" "unprognostic (3.52e-1)" "unprognostic (1.10e-1)" "unprognostic (1.82e-1)" "unprognostic (1.01e-1)" "unprognostic (2.65e-2)" "unprognostic (1.23e-1)" "unprognostic (6.34e-3)" "unprognostic (3.36e-2)" "unprognostic (1.73e-1)" "unprognostic (1.47e-2)" "unprognostic (1.38e-1)" "unprognostic (1.50e-1)" "unprognostic (9.61e-2)" "unprognostic (5.65e-1)" "unprognostic (3.75e-2)" "unprognostic (3.48e-1)" "unprognostic (2.74e-1)" "unprognostic (2.60e-1)" "unprognostic (5.29e-2)" "unprognostic (1.33e-1)" "unprognostic (2.39e-1)" RUSC1 NESCA ENSG00000160753 "RUN and SH3 domain containing 1" Q9BVN2 1 155320894-155331114 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 140.9;Esophageal suprabasal cells: 77.2;Extravillous trophoblasts: 97.1;Oocytes: 82.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Fibroblasts_1, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028510, HPA029922, HPA029923" Approved Enhanced Nucleoplasm,Vesicles,Cytosol NA Yes "Cluster 42: Non-specific - Vesicular transport" "Cluster 64: Non-specific - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 97: Non-specific - Cellular respiration" 71 Cytosol "Nucleoplasm, Vesicles" "HPA028510: , HPA029922: , HPA029923: " "unprognostic (2.12e-1)" "unprognostic (6.31e-2)" "unprognostic (1.14e-1)" "unprognostic (3.46e-2)" "unprognostic (8.99e-2)" "unprognostic (9.39e-3)" "unprognostic (4.66e-2)" "unprognostic (1.33e-2)" "unprognostic (1.42e-1)" "unprognostic (6.15e-2)" "unprognostic (1.11e-1)" "unprognostic (2.47e-2)" "potential prognostic unfavorable (1.34e-4)" "potential prognostic unfavorable (7.50e-6)" "unprognostic (5.45e-3)" "potential prognostic unfavorable (1.31e-4)" "unprognostic (5.39e-3)" "unprognostic (8.34e-3)" "unprognostic (1.67e-1)" "unprognostic (1.30e-1)" "unprognostic (9.16e-3)" "unprognostic (4.70e-2)" "unprognostic (1.62e-1)" "potential prognostic unfavorable (6.18e-4)" "unprognostic (2.62e-1)" "unprognostic (2.47e-1)" "unprognostic (5.08e-2)" "unprognostic (4.10e-2)" "unprognostic (4.37e-2)" "unprognostic (2.23e-2)" "unprognostic (3.84e-2)" RUSC2 KIAA0375 ENSG00000198853 "RUN and SH3 domain containing 2" Q8N2Y8 9 35490111-35561898 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 217.0;Myonuclei: 345.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "basophil: 3.1" "Lineage enriched" "Detected in single" 4 "granulocytes: 3.1" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021297 Uncertain NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 53: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 8 "HPA021297: " "unprognostic (1.64e-2)" "unprognostic (2.75e-1)" "unprognostic (6.26e-2)" "unprognostic (1.66e-2)" "unprognostic (8.59e-2)" "potential prognostic unfavorable (6.18e-4)" "unprognostic (3.56e-1)" "unprognostic (1.92e-2)" "unprognostic (1.90e-1)" "unprognostic (1.53e-2)" "potential prognostic favorable (1.07e-6)" "unprognostic (3.72e-2)" "unprognostic (1.05e-2)" "unprognostic (1.98e-2)" "unprognostic (1.35e-2)" "unprognostic (8.44e-2)" "unprognostic (4.08e-2)" "unprognostic (6.38e-2)" "unprognostic (2.63e-1)" "unprognostic (1.38e-2)" "unprognostic (4.19e-2)" "unprognostic (4.61e-2)" "unprognostic (1.59e-1)" "unprognostic (2.16e-2)" "unprognostic (2.01e-1)" "unprognostic (7.74e-3)" "unprognostic (4.07e-1)" "unprognostic (1.85e-2)" "unprognostic (1.18e-1)" "unprognostic (1.80e-2)" "unprognostic (3.17e-2)" RUSF1 "C16orf58, FLJ13868" ENSG00000140688 "RUS family member 1" Q96GQ5 16 31489471-31509309 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024406 Uncertain Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 70: Non-specific - Protein processing" "Cluster 14: Neurons - Synaptic function" "Cluster 54: Non-specific - Transcription" "Cluster 8: Non-specific - Secretory pathway" 77 "Nucleoli, Golgi apparatus, Vesicles" "Nucleoplasm, Cytosol" "HPA024406: " "unprognostic (3.28e-2)" "unprognostic (1.30e-3)" "unprognostic (3.24e-2)" "unprognostic (1.32e-1)" "unprognostic (1.79e-2)" "unprognostic (2.50e-2)" "unprognostic (8.73e-2)" "unprognostic (6.91e-3)" "unprognostic (2.31e-1)" "potential prognostic favorable (1.95e-4)" "unprognostic (2.47e-1)" "unprognostic (3.07e-1)" "unprognostic (1.15e-1)" "unprognostic (8.90e-2)" "unprognostic (2.62e-1)" "unprognostic (6.72e-2)" "unprognostic (2.61e-2)" "unprognostic (1.39e-1)" "unprognostic (8.13e-2)" "unprognostic (2.80e-2)" "unprognostic (6.32e-2)" "unprognostic (1.65e-1)" "unprognostic (3.31e-2)" "unprognostic (5.92e-2)" "unprognostic (8.35e-2)" "unprognostic (2.36e-1)" "unprognostic (1.65e-1)" "unprognostic (2.34e-1)" "unprognostic (3.58e-2)" RUVBL1 "ECP54, INO80H, NMP238, Pontin52, RVB1, TIH1, TIP49, TIP49a" ENSG00000175792 "RuvB like AAA ATPase 1" Q9Y265 3 128064778-128153914 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA recombination, DNA repair, Growth regulation, Mitosis, Transcription, Transcription regulation" "Activator, Chromatin regulator, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epicardial cells: 325.2;Fallopian tube ciliated cells: 274.6;Respiratory ciliated cells: 272.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019947, HPA019948" Enhanced Supported "Nucleoplasm,Nuclear speckles,Basal body,Cytosol" NA NA 210000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 3: Choroid plexus - Cilium" "Cluster 63: Non-specific - Protein processing" "Cluster 107: Ciliated cells - Cilia assembly & function" 265 "Nucleoplasm, Nuclear speckles" "Basal body, Cytosol" "HPA019947: , HPA019948: " "unprognostic (3.23e-2)" "unprognostic (7.66e-2)" "unprognostic (9.62e-2)" "unprognostic (2.10e-1)" "unprognostic (8.89e-3)" "unprognostic (1.52e-1)" "unprognostic (2.28e-1)" "unprognostic (1.51e-2)" "unprognostic (2.06e-2)" "unprognostic (5.45e-3)" "unprognostic (1.45e-2)" "unprognostic (2.21e-1)" "unprognostic (1.23e-2)" "validated prognostic unfavorable (6.86e-10)" "validated prognostic unfavorable (5.43e-4)" "unprognostic (1.17e-2)" "unprognostic (4.33e-3)" "unprognostic (2.54e-1)" "unprognostic (2.24e-1)" "unprognostic (2.32e-2)" "unprognostic (1.61e-1)" "unprognostic (2.24e-3)" "unprognostic (1.04e-1)" "unprognostic (1.79e-2)" "unprognostic (4.77e-2)" "unprognostic (4.38e-2)" "unprognostic (1.46e-2)" "unprognostic (1.79e-1)" "unprognostic (3.72e-1)" "unprognostic (8.20e-2)" "unprognostic (1.40e-1)" RUVBL2 "ECP51, INO80J, Reptin52, RVB2, TIH2, TIP48, TIP49b" ENSG00000183207 "RuvB like AAA ATPase 2" Q9Y230 19 48993562-49015970 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Growth regulation, Transcription, Transcription regulation" "Activator, Chromatin regulator, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 232.1" "Cell type enhanced" "Detected in many" "Early spermatids: 588.2;Fallopian tube ciliated cells: 300.7;Late primary spermatocytes: 918.0;Late spermatids: 1436.5;Respiratory ciliated cells: 275.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012432, HPA042880, HPA067966" Enhanced Supported "Nucleoplasm,Centrosome,Basal body,Cytosol" NA NA 150000 "Cluster 13: Non-specific - Mitochondria" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 21: Non-specific - Metabolism" "Cluster 4: Non-specific - Transcription" "Cluster 107: Ciliated cells - Cilia assembly & function" 356 "Nucleoplasm, Cytosol" "Centrosome, Basal body" "CAB012432: , HPA042880: , HPA067966: " "unprognostic (1.96e-2)" "unprognostic (1.41e-1)" "unprognostic (4.43e-3)" "unprognostic (1.54e-2)" "unprognostic (2.01e-2)" "unprognostic (2.69e-1)" "unprognostic (2.53e-1)" "unprognostic (2.14e-1)" "potential prognostic unfavorable (7.55e-4)" "unprognostic (7.23e-2)" "unprognostic (1.43e-1)" "unprognostic (1.34e-1)" "unprognostic (9.68e-3)" "validated prognostic unfavorable (1.58e-6)" "validated prognostic unfavorable (4.22e-4)" "potential prognostic unfavorable (1.24e-5)" "unprognostic (5.60e-2)" "unprognostic (8.33e-2)" "unprognostic (1.48e-1)" "unprognostic (7.01e-2)" "unprognostic (1.21e-1)" "unprognostic (1.52e-1)" "unprognostic (2.86e-1)" "unprognostic (8.21e-2)" "unprognostic (8.24e-2)" "unprognostic (9.94e-2)" "unprognostic (6.27e-2)" "unprognostic (3.33e-1)" "unprognostic (4.68e-2)" "unprognostic (1.80e-1)" "unprognostic (2.55e-1)" RWDD1 PTD013 ENSG00000111832 "RWD domain containing 1" Q9H446 6 116571409-116597675 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028712, HPA028713" Approved NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 97: Non-specific - Cellular respiration" 9 "HPA028712: , HPA028713: " "unprognostic (7.41e-2)" "unprognostic (2.68e-3)" "unprognostic (1.49e-2)" "unprognostic (5.57e-2)" "unprognostic (1.27e-1)" "unprognostic (9.70e-2)" "unprognostic (8.52e-2)" "unprognostic (1.78e-1)" "unprognostic (6.58e-3)" "unprognostic (2.14e-3)" "potential prognostic favorable (1.51e-4)" "unprognostic (1.83e-1)" "unprognostic (2.79e-1)" "potential prognostic unfavorable (7.48e-4)" "unprognostic (1.19e-3)" "unprognostic (5.06e-2)" "unprognostic (4.33e-2)" "unprognostic (2.15e-1)" "unprognostic (3.57e-1)" "unprognostic (3.27e-2)" "unprognostic (1.33e-2)" "unprognostic (1.48e-1)" "unprognostic (6.87e-2)" "unprognostic (8.22e-3)" "unprognostic (4.79e-1)" "unprognostic (1.66e-1)" "unprognostic (1.61e-2)" "unprognostic (1.47e-1)" "unprognostic (5.11e-2)" "unprognostic (1.81e-2)" "unprognostic (1.52e-1)" RWDD2A "dJ747H23.2, MGC13523, RWDD2" ENSG00000013392 "RWD domain containing 2A" Q9UIY3 6 83193357-83198935 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 33.2;Late primary spermatocytes: 128.8;Prostatic glandular cells: 44.2;Retinal pigment epithelial cells: 25.6" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 16.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Prostate - Prostate glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030105, HPA030106, HPA030107" Uncertain Approved Vesicles NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 22: Epididymis - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 60: Prostate cancer - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 4 Vesicles "HPA030105: , HPA030106: , HPA030107: " "unprognostic (1.51e-1)" "unprognostic (1.93e-3)" "unprognostic (2.30e-1)" "unprognostic (3.60e-2)" "unprognostic (1.27e-1)" "unprognostic (2.43e-1)" "unprognostic (2.75e-2)" "unprognostic (1.67e-2)" "unprognostic (2.39e-2)" "unprognostic (1.25e-2)" "unprognostic (6.88e-3)" "potential prognostic favorable (7.27e-5)" "unprognostic (2.42e-2)" "unprognostic (4.19e-2)" "unprognostic (6.86e-2)" "unprognostic (2.38e-2)" "unprognostic (1.92e-1)" "unprognostic (2.98e-1)" "unprognostic (9.20e-3)" "potential prognostic favorable (8.83e-4)" "unprognostic (6.68e-2)" "potential prognostic favorable (2.27e-5)" "unprognostic (8.29e-2)" "unprognostic (3.00e-2)" "potential prognostic favorable (2.98e-4)" "unprognostic (2.07e-1)" "unprognostic (1.85e-1)" "unprognostic (4.58e-2)" "unprognostic (6.72e-2)" "unprognostic (4.03e-3)" "unprognostic (2.97e-2)" RWDD2B "C21orf6, GL011" ENSG00000156253 "RWD domain containing 2B" P57060 21 29004384-29019360 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 39.8;Late primary spermatocytes: 38.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018316 Uncertain NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 37: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 97: Non-specific - Cellular respiration" 13 "HPA018316: " "unprognostic (3.56e-2)" "potential prognostic unfavorable (2.16e-4)" "unprognostic (1.90e-1)" "unprognostic (2.05e-2)" "unprognostic (1.34e-1)" "unprognostic (2.49e-1)" "unprognostic (4.75e-3)" "unprognostic (1.58e-2)" "unprognostic (1.45e-1)" "unprognostic (2.08e-2)" "unprognostic (2.39e-1)" "unprognostic (8.28e-2)" "unprognostic (1.87e-2)" "unprognostic (3.99e-3)" "unprognostic (9.25e-2)" "unprognostic (3.07e-1)" "unprognostic (2.76e-1)" "unprognostic (3.52e-2)" "unprognostic (1.38e-1)" "unprognostic (1.13e-1)" "unprognostic (3.46e-2)" RWDD3 "DKFZP566K023, RSUME" ENSG00000122481 "RWD domain containing 3" Q9Y3V2 1 95234210-95247225 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 52.4;Bergmann glia: 39.7;Brain excitatory neurons: 20.3;Brain inhibitory neurons: 25.0;Choroid plexus epithelial cells: 29.0;Ependymal cells: 20.0;Megakaryocytes: 12.4;Microglia: 32.4;Oligodendrocyte progenitor cells: 35.8;Oligodendrocytes: 33.4;Other brain neurons: 18.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 75: Ovary - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 22: Non-specific - Basic cellular functions" 5 "unprognostic (1.85e-1)" "unprognostic (1.36e-1)" "unprognostic (4.43e-2)" "unprognostic (2.80e-1)" "unprognostic (2.21e-1)" "unprognostic (5.51e-2)" "unprognostic (1.23e-2)" "unprognostic (5.89e-2)" "unprognostic (1.78e-1)" "unprognostic (4.51e-1)" "unprognostic (7.21e-3)" "unprognostic (2.65e-2)" "unprognostic (6.34e-2)" "unprognostic (2.36e-2)" "unprognostic (9.26e-2)" "unprognostic (2.33e-1)" "unprognostic (2.83e-1)" "unprognostic (3.98e-2)" "unprognostic (1.91e-1)" "unprognostic (6.26e-2)" "unprognostic (2.75e-2)" "unprognostic (3.55e-2)" "unprognostic (1.37e-2)" "unprognostic (5.26e-2)" "unprognostic (1.31e-2)" "unprognostic (3.86e-2)" "unprognostic (5.19e-3)" "unprognostic (3.44e-1)" "unprognostic (6.21e-2)" "unprognostic (3.10e-1)" "unprognostic (3.53e-2)" RWDD4 "FAM28A, MGC10198, RWDD4A" ENSG00000182552 "RWD domain containing 4" Q6NW29 4 183639635-183659203 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036501, HPA036502" Approved Approved "Intermediate filaments" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 94: Gonadal somatic cells - Mixed function" 10 "Intermediate filaments" "HPA036501: , HPA036502: " "unprognostic (3.30e-2)" "unprognostic (8.59e-2)" "unprognostic (6.64e-3)" "unprognostic (3.33e-2)" "unprognostic (6.00e-2)" "unprognostic (1.92e-1)" "unprognostic (1.04e-1)" "unprognostic (2.11e-1)" "unprognostic (1.03e-1)" "potential prognostic favorable (5.88e-6)" "unprognostic (2.59e-2)" "unprognostic (1.30e-2)" "unprognostic (1.51e-1)" "unprognostic (4.00e-1)" "unprognostic (4.00e-3)" "unprognostic (1.62e-1)" "unprognostic (1.18e-1)" "unprognostic (1.01e-1)" "unprognostic (3.77e-1)" "unprognostic (2.48e-1)" "unprognostic (5.12e-1)" "unprognostic (3.60e-2)" "unprognostic (1.46e-1)" "unprognostic (2.64e-1)" "unprognostic (1.46e-1)" "unprognostic (2.36e-1)" "unprognostic (2.28e-1)" "unprognostic (1.08e-1)" "unprognostic (9.16e-3)" "unprognostic (1.32e-1)" RXFP1 "LGR7, RXFPR1" ENSG00000171509 "Relaxin family peptide receptor 1" Q9HBX9 4 158315311-158653372 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 13.3;endometrium 1: 5.9" "Group enriched" "Detected in many" 7 "Endometrial ciliated cells: 134.2;Endometrial glandular cells: 534.9;Endometrial luminal cells: 364.6" "Group enriched" "Detected in many" 4 "deep-layer corticothalamic and 6b: 386.5;deep-layer intratelencephalic: 310.1;eccentric medium spiny neuron: 431.9" "Cancer enriched" "Detected in some" 5 "Uterine Corpus Endometrial Carcinoma (TCGA): 6.4" "Group enriched" "Detected in many" 5 "basal ganglia: 12.0;cerebral cortex: 14.4;hypothalamus: 5.2;white matter: 10.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "liver cancer: 6.6;ovarian cancer: 23.1;Uterine cancer: 13.5" "Adrenal gland - Fibroblasts" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "cerebral cortex: 14.4;hippocampal formation: 9.3" HPA027067 Approved NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" "HPA027067: " "unprognostic (1.36e-1)" "validated prognostic favorable (8.81e-7)" "validated prognostic favorable (4.34e-4)" "potential prognostic favorable (7.58e-4)" "unprognostic (2.63e-1)" "unprognostic (5.68e-2)" RXFP2 "GPR106, GREAT, INSL3R, LGR8, RXFPR2" ENSG00000133105 "Relaxin family peptide receptor 2" Q8WXD0 13 31739526-31803389 "Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 2.1;Brain inhibitory neurons: 4.7;Cardiomyocytes: 4.3;Early spermatids: 6.6;Late primary spermatocytes: 8.0;Mesothelial cells: 1.3;Monocyte progenitors: 1.8;Other brain neurons: 2.7;Platelets: 2.8;Suprabasal keratinocytes: 1.4" "Cell type enhanced" "Detected in some" "deep-layer corticothalamic and 6b: 10.3;deep-layer intratelencephalic: 16.9;hippocampal CA1-3: 10.4;medium spiny neuron: 12.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 10 "classical monocyte: 1.7" "Lineage enriched" "Detected in single" 18 "monocytes: 1.7" "Cancer enhanced" "Detected in single" "Sarcoma: 1.0" "Testis - Early spermatids" "Not detected" "Not detected" "Region enriched" "Detected in single" 10 "basal ganglia: 3.8" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 33: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 35: Neurons - Synaptic function & neurogenesis" RXFP3 "GPCR135, RLN3R1, RXFPR3, SALPR" ENSG00000182631 "Relaxin family peptide receptor 3" Q9NSD7 5 33936386-33938918 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA027833 Uncertain NA NA "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 11: Neuronal - Sensory perception" 1 "HPA027833: " RXFP4 "GPCR142, GPR100, RLN3R2, RXFPR4" ENSG00000173080 "Relaxin family peptide/INSL5 receptor 4" Q8TDU9 1 155941638-155943087 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "intestine: 1.8" "Cell type enriched" "Detected in some" 10 "Neuroendocrine cells: 51.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Colon Adenocarcinoma (TCGA): 2.6;Rectum Adenocarcinoma (TCGA): 3.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 2.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 77: Intestine - Digestion" "Cluster 15: Non-specific - Transcription" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" 1 "unprognostic (1.18e-1)" "unprognostic (2.62e-2)" "unprognostic (3.57e-1)" "unprognostic (1.07e-1)" "unprognostic (2.99e-1)" RXRA "NR2B1, RXR-alpha, RXRalpha" ENSG00000186350 "Retinoid X receptor alpha" P19793 9 134317098-134440585 "Cancer-related genes, FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 162.8;Hepatocytes: 248.8;Kupffer cells: 188.6;monocytes: 150.3;Neutrophils: 313.7;Thymic myoid cells: 156.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 19.6" "Group enriched" "Detected in many" 5 "granulocytes: 19.6;monocytes: 12.9" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004565, CAB005352" Supported Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 24: Non-specific - Transcription" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 73 Nucleoplasm "Golgi apparatus" "CAB004565: , CAB005352: " "unprognostic (3.27e-1)" "unprognostic (2.26e-1)" "unprognostic (2.21e-2)" "unprognostic (2.89e-1)" "unprognostic (3.49e-1)" "unprognostic (6.29e-2)" "unprognostic (5.45e-2)" "unprognostic (1.35e-1)" "unprognostic (6.55e-3)" "unprognostic (2.83e-2)" "potential prognostic favorable (3.29e-6)" "unprognostic (7.10e-3)" "unprognostic (2.25e-2)" "unprognostic (3.73e-1)" "unprognostic (6.75e-2)" "unprognostic (2.03e-2)" "unprognostic (4.91e-3)" "unprognostic (1.51e-2)" "unprognostic (3.32e-1)" "unprognostic (5.58e-3)" "unprognostic (1.66e-2)" "unprognostic (3.94e-3)" "unprognostic (2.37e-1)" "unprognostic (1.05e-1)" "unprognostic (8.33e-2)" "unprognostic (1.02e-2)" "unprognostic (1.86e-2)" "unprognostic (6.63e-2)" "unprognostic (2.59e-1)" "unprognostic (3.88e-2)" "unprognostic (2.09e-1)" RXRB "H-2RIIBP, NR2B2, RCoR-1, RXR-beta, RXRbeta" ENSG00000204231 "Retinoid X receptor beta" P28702 6 33193588-33200665 "Cancer-related genes, FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 16.5;Bergmann glia: 19.2;Brain excitatory neurons: 17.7;Brain inhibitory neurons: 17.1;Choroid plexus epithelial cells: 9.0;Distal convoluted tubule cells: 12.1;Ependymal cells: 11.0;Loop of henle epithelial cells: 10.9;Microglia: 14.3;Oligodendrocyte progenitor cells: 16.7;Oligodendrocytes: 19.8;Other brain neurons: 16.1;Podocytes: 11.6;Proximal tubule cells: 15.9;Renal collecting duct intercalated cells: 11.8;Renal collecting duct principal cells: 9.4;Renal connecting tubule cells: 12.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002003, HPA071592, HPA075035" Supported Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 102: Non-specific - Mixed function" 27 Nucleoplasm "Nucleoli, Cytosol" "CAB002003: , HPA071592: , HPA075035: " "unprognostic (2.84e-2)" "unprognostic (3.51e-1)" "unprognostic (1.91e-1)" "unprognostic (2.30e-1)" "unprognostic (3.82e-1)" "unprognostic (3.31e-1)" "unprognostic (2.01e-2)" "potential prognostic favorable (4.82e-4)" "unprognostic (1.68e-2)" "unprognostic (3.32e-1)" "unprognostic (3.83e-2)" "unprognostic (7.15e-2)" "unprognostic (1.58e-2)" "unprognostic (1.94e-1)" "unprognostic (2.14e-2)" "unprognostic (2.19e-1)" "unprognostic (3.21e-2)" "unprognostic (2.45e-1)" "unprognostic (3.81e-1)" "unprognostic (2.13e-1)" "unprognostic (3.82e-2)" "unprognostic (1.18e-2)" "unprognostic (1.79e-1)" "unprognostic (2.78e-1)" "potential prognostic unfavorable (2.82e-4)" "unprognostic (1.01e-2)" "unprognostic (1.61e-1)" "unprognostic (2.65e-1)" "unprognostic (9.84e-2)" "unprognostic (1.09e-1)" RXRG "NR2B3, RXR-gamma, RXRgamma" ENSG00000143171 "Retinoid X receptor gamma" P48443 1 165400922-165445355 "Cancer-related genes, FDA approved drug targets, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 29.6;retina: 22.5;skeletal muscle: 46.6" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 134.6;Melanocytes: 26.8;Myonuclei: 22.3;Myosatellite cells: 60.2;Retinal ganglion cells: 54.1;Schwann cells: 37.7;Somatotrophs: 143.4;Thyrotrophs: 40.6" "Cell type enhanced" "Detected in many" "eccentric medium spiny neuron: 44.3;medium spiny neuron: 29.6" "Group enriched" "Detected in many" 16 "Skin Cutaneous Melanoma (TCGA): 55.9;Thyroid Carcinoma (TCGA): 68.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "skin cancer: 29.7" "Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Minor Salivary Gland - Fibroblasts, Pancreas - Beta cells, Pituitary gland - Somatotropes, Skeletal muscle - Skeletal myocytes, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Region enriched" "Detected in many" 5 "basal ganglia: 100.2" "Low region specificity" "Detected in many" "CAB002615, HPA012933" Uncertain Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 28 "Nucleoplasm, Nuclear bodies" "CAB002615: , HPA012933: " "unprognostic (2.35e-1)" "unprognostic (7.25e-2)" "unprognostic (5.41e-2)" "unprognostic (1.27e-1)" "potential prognostic favorable (6.76e-4)" "unprognostic (2.75e-3)" "unprognostic (5.39e-2)" "unprognostic (2.94e-2)" "unprognostic (3.55e-1)" "unprognostic (7.94e-2)" "unprognostic (1.00e-3)" "unprognostic (7.83e-2)" RXYLT1 "HP10481, TMEM5" ENSG00000118600 "Ribitol xylosyltransferase 1" Q9Y2B1 12 63779833-63809792 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Transferase "Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 114.1;Late primary spermatocytes: 190.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064014 Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 35: Non-specific - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" 6 "Nucleoplasm, Golgi apparatus" "HPA064014: " "unprognostic (7.38e-3)" "unprognostic (4.35e-2)" "unprognostic (4.11e-2)" "unprognostic (4.75e-1)" "unprognostic (1.09e-1)" "unprognostic (1.30e-1)" "unprognostic (1.81e-2)" "unprognostic (8.72e-2)" "unprognostic (3.50e-3)" "potential prognostic favorable (4.67e-6)" "unprognostic (1.38e-1)" "unprognostic (2.31e-1)" "potential prognostic unfavorable (1.34e-4)" "potential prognostic unfavorable (3.22e-4)" "unprognostic (3.39e-1)" "unprognostic (7.20e-2)" "unprognostic (1.69e-1)" "unprognostic (3.79e-1)" "unprognostic (1.61e-1)" "unprognostic (8.36e-2)" "unprognostic (1.24e-1)" "unprognostic (3.36e-2)" "potential prognostic favorable (4.85e-7)" "unprognostic (1.82e-1)" "potential prognostic unfavorable (3.24e-5)" "unprognostic (1.03e-2)" "unprognostic (1.68e-1)" "unprognostic (3.30e-1)" "unprognostic (1.25e-1)" RYBP "AAP1, DEDAF, YEAF1" ENSG00000163602 "RING1 and YY1 binding protein" Q8N488 3 72371825-72446621 "Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 114.8;Oligodendrocytes: 592.0;Papillary tip epithelial cells: 104.9;Platelets: 157.6;Renal collecting duct principal cells: 109.9;Renal connecting tubule cells: 109.4" "Cell type enhanced" "Detected in all" "oligodendrocyte: 764.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053357 Approved Supported Nucleoplasm NA No "Cluster 65: Brain - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 80: Oligodendrocytes - Myelination" 124 Nucleoplasm "HPA053357: " "unprognostic (3.06e-1)" "unprognostic (3.28e-1)" "unprognostic (4.25e-2)" "unprognostic (3.60e-1)" "unprognostic (1.18e-1)" "potential prognostic favorable (3.57e-4)" "unprognostic (6.09e-2)" "unprognostic (3.65e-3)" "unprognostic (1.80e-1)" "unprognostic (1.08e-2)" "unprognostic (1.48e-1)" "unprognostic (2.07e-1)" "unprognostic (4.58e-2)" RYK "D3S3195, JTK5, JTK5A, RYK1" ENSG00000163785 "Receptor like tyrosine kinase" P34925 3 134065303-134250859 "Enzymes, Predicted membrane proteins" "Wnt signaling pathway" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034117, HPA045503, HPA075430, CAB080389" Approved Approved "Golgi apparatus,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 7: Non-specific - Ribosome" "Cluster 63: Non-specific - Protein processing" "Cluster 7: Non-specific - Transcription" 36 "Golgi apparatus" Cytosol "CAB034117: , CAB080389: , HPA045503: , HPA075430: " "unprognostic (2.16e-1)" "unprognostic (8.96e-2)" "unprognostic (3.96e-2)" "unprognostic (3.59e-2)" "unprognostic (1.18e-1)" "unprognostic (1.60e-1)" "unprognostic (1.10e-1)" "unprognostic (6.92e-2)" "unprognostic (2.97e-1)" "unprognostic (1.41e-2)" "unprognostic (1.27e-2)" "unprognostic (7.74e-3)" "unprognostic (3.47e-2)" "potential prognostic unfavorable (3.76e-4)" "unprognostic (2.77e-2)" "unprognostic (1.52e-1)" "unprognostic (5.12e-2)" "unprognostic (1.27e-1)" "unprognostic (3.91e-2)" "unprognostic (4.62e-1)" "unprognostic (7.91e-3)" "unprognostic (3.07e-3)" "unprognostic (8.04e-3)" "unprognostic (1.90e-1)" "unprognostic (2.99e-3)" "unprognostic (1.87e-1)" "unprognostic (1.04e-1)" "unprognostic (1.73e-1)" "unprognostic (1.84e-1)" "unprognostic (1.38e-1)" "unprognostic (1.48e-1)" RYR1 "CCO, MHS, MHS1, PPP1R137, RYR" ENSG00000196218 "Ryanodine receptor 1" P21817 19 38433691-38595273 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Calmodulin-binding, Developmental protein, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 25 "skeletal muscle: 1065.7;tongue: 322.3" "Cell type enriched" "Detected in many" 8 "Myonuclei: 3145.9" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 353.0;cerebellar inhibitory: 239.5" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 43.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "dendritic cells: 3.3;granulocytes: 3.3;monocytes: 4.3" "Cancer enhanced" "Detected in many" "cervical cancer: 21.0" "Adrenal gland - Macrophages, Colon - Enteric glia cells" "Low region specificity" "Detected in single" "Region enhanced" "Detected in many" "basal ganglia: 12.6" HPA056416 Enhanced Approved "Golgi apparatus,Vesicles,Cytosol" NA NA 15000 "Cluster 40: Monocytes - Innate immune response" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 10 "Golgi apparatus, Vesicles" Cytosol "HPA056416: " "unprognostic (7.05e-2)" "unprognostic (2.20e-3)" "unprognostic (2.11e-1)" "unprognostic (1.87e-1)" "unprognostic (8.70e-2)" "unprognostic (1.70e-3)" "unprognostic (1.46e-1)" "unprognostic (1.12e-1)" "unprognostic (2.81e-1)" "unprognostic (4.03e-1)" "unprognostic (4.70e-2)" "unprognostic (1.73e-1)" "unprognostic (1.87e-2)" "unprognostic (1.23e-1)" "unprognostic (1.39e-1)" "unprognostic (2.76e-3)" "unprognostic (8.37e-2)" "unprognostic (1.60e-1)" "unprognostic (8.68e-3)" "unprognostic (9.32e-2)" "unprognostic (5.12e-2)" "unprognostic (1.53e-2)" "unprognostic (2.65e-1)" "unprognostic (1.16e-2)" "unprognostic (2.73e-3)" RYR2 "ARVC2, ARVD2, VTSIP" ENSG00000198626 "Ryanodine receptor 2" Q92736 1 237042184-237833988 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Calmodulin-binding, Developmental protein, Ion channel, Ligand-gated ion channel, Receptor" "Cardiomyopathy, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "heart muscle: 137.9" "Cell type enriched" "Detected in many" 17 "Cardiomyocytes: 30129.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "thyroid cancer: 4.1" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Heart muscle - Cardiomyocytes, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020028 Approved Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 34: Non-specific - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 13 "Plasma membrane" "Nucleoplasm, Cytosol" "HPA020028: " "unprognostic (9.88e-3)" "unprognostic (6.89e-2)" "unprognostic (1.35e-1)" "unprognostic (7.28e-2)" "unprognostic (3.20e-2)" "unprognostic (9.99e-2)" "unprognostic (1.57e-2)" "unprognostic (6.17e-2)" "unprognostic (2.35e-2)" "unprognostic (1.73e-1)" RYR3 ENSG00000198838 "Ryanodine receptor 3" Q15413 15 33310962-33866121 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Calcium channel, Calmodulin-binding, Ion channel, Ligand-gated ion channel, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.4;choroid plexus: 27.9;skeletal muscle: 22.6;tongue: 41.1" "Cell type enhanced" "Detected in many" "Astrocytes: 1440.6;Bergmann glia: 978.9;Brain inhibitory neurons: 576.7;Choroid plexus epithelial cells: 1134.0;Gonadotrophs: 512.9;Megakaryocyte-Erythroid progenitors: 1227.4;Myonuclei: 1899.2;Myosatellite cells: 682.8;Podocytes: 1227.5;Retinal amacrine cells: 496.4;Retinal horizontal cells: 1107.9" "Cell type enhanced" "Detected in all" "astrocyte: 1827.7" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 5.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 19 "basophil: 1.9" "Lineage enriched" "Detected in single" 19 "granulocytes: 1.9" "Cancer enhanced" "Detected in some" "testis cancer: 2.6" "Adipose subcutaneous - Smooth muscle cells, Pituitary gland - Gonadotropes" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "basal ganglia: 30.4" HPA062004 Approved Vesicles NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 55: Myocytes - Oxidative muscle function" 2 Vesicles "HPA062004: " "unprognostic (2.87e-2)" "unprognostic (8.15e-2)" "unprognostic (5.47e-3)" "potential prognostic unfavorable (4.06e-5)" "unprognostic (4.71e-2)" "unprognostic (1.17e-1)" "unprognostic (2.73e-1)" "unprognostic (1.27e-3)" "unprognostic (1.46e-1)" S100A1 "S100-alpha, S100A" ENSG00000160678 "S100 calcium binding protein A1" P23297 1 153627926-153632039 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "brain: 1266.4;heart muscle: 2882.1;skeletal muscle: 2868.7;tongue: 4577.6" "Cell type enhanced" "Detected in many" "Breast lactating cells: 1751.0;Breast secretory cells: 341.5;Endometrial glandular cells: 202.0;Endometrial luminal cells: 163.6;Hofbauer cells: 449.1;Lacrimal acinar cells: 461.1;Melanocytes: 208.7;Salivary acinar cells: 470.7;Thymic myoid cells: 186.3" "Group enriched" "Detected in many" 5 "astrocyte: 91.3;committed oligodendrocyte precursor: 76.1;oligodendrocyte: 171.7" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 2441.2;Thyroid Carcinoma (TCGA): 1378.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Rhabdoid: 334.3;skin cancer: 729.5" "Heart muscle - Cardiomyocytes, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002599, HPA006462" Enhanced Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 220000 "Cluster 41: Striated muscle - Muscle contraction" "Cluster 19: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 4: Breast lactating luminal cells - Lactation" 28 Cytosol "Nucleoplasm, Golgi apparatus" "CAB002599: , HPA006462: " "unprognostic (1.90e-1)" "unprognostic (3.11e-2)" "unprognostic (5.26e-2)" "unprognostic (1.94e-1)" "potential prognostic unfavorable (7.83e-4)" "unprognostic (1.62e-1)" "unprognostic (1.88e-1)" "unprognostic (2.88e-2)" "unprognostic (4.23e-2)" "unprognostic (5.17e-3)" "unprognostic (2.39e-2)" "unprognostic (3.23e-2)" "unprognostic (7.68e-2)" "unprognostic (9.82e-2)" "unprognostic (7.70e-2)" "unprognostic (2.67e-2)" "unprognostic (1.14e-1)" "unprognostic (1.37e-2)" "unprognostic (2.24e-1)" "unprognostic (3.24e-1)" "unprognostic (1.45e-3)" "validated prognostic favorable (3.48e-4)" "validated prognostic favorable (1.15e-4)" "potential prognostic favorable (2.63e-4)" "unprognostic (4.81e-2)" "unprognostic (1.77e-2)" "unprognostic (4.78e-2)" "unprognostic (4.12e-2)" "unprognostic (1.29e-2)" "unprognostic (3.73e-3)" "unprognostic (8.73e-2)" S100A10 "42C, ANX2LG, CAL1L, CLP11, P11" ENSG00000197747 "S100 calcium binding protein A10" P60903 1 151982915-151993859 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 2017.3" "Cell type enriched" "Detected in many" 4 "Esophageal apical cells: 40253.4" "Cell type enhanced" "Detected in many" "endothelial cell: 193.8;ependymal cell: 115.9;leukocyte: 96.3;lower rhombic lip: 97.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 2009.9;monocytes: 1239.0;T-cells: 1183.5" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Kidney - Endothelial cells, Skeletal muscle - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003340, CAB025484" Enhanced Approved Mitochondria Yes No 640000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 84: Apical squamous epithelium - Cornification" 29 Mitochondria "CAB025484: , HPA003340: " "unprognostic (4.73e-3)" "unprognostic (2.07e-1)" "unprognostic (4.15e-1)" "unprognostic (1.04e-3)" "unprognostic (5.01e-2)" "unprognostic (1.33e-1)" "unprognostic (2.42e-2)" "unprognostic (5.32e-3)" "unprognostic (5.12e-3)" "unprognostic (3.44e-2)" "unprognostic (1.26e-2)" "unprognostic (4.40e-2)" "unprognostic (3.67e-3)" "potential prognostic unfavorable (1.24e-4)" "unprognostic (2.16e-3)" "potential prognostic unfavorable (1.75e-6)" "unprognostic (6.65e-3)" "unprognostic (4.95e-2)" "unprognostic (7.26e-3)" "unprognostic (5.79e-2)" "unprognostic (1.52e-1)" "potential prognostic unfavorable (5.07e-5)" "unprognostic (2.72e-2)" "unprognostic (2.31e-2)" "unprognostic (2.95e-1)" "unprognostic (3.88e-2)" "unprognostic (8.44e-3)" "unprognostic (1.85e-1)" "unprognostic (4.70e-1)" "unprognostic (6.87e-2)" "unprognostic (1.82e-1)" S100A11 S100C ENSG00000163191 "S100 calcium binding protein A11" P31949 1 152032506-152047907 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 4984.0" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 45082.4;Esophageal basal cells: 6382.9;Esophageal suprabasal cells: 19553.4;Extravillous trophoblasts: 8453.0;Neutrophils: 7787.5;Suprabasal keratinocytes: 5206.8" "Group enriched" "Detected in some" 5 "central nervous system macrophage: 104.7;endothelial cell: 87.2;fibroblast: 80.9;leukocyte: 98.4;pericyte: 115.3;vascular associated smooth muscle cell: 138.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 17941.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034320, HPA042745" Enhanced Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA 4800000 "Cluster 21: Neutrophils - Unknown function" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 13 "Nucleoplasm, Cytosol" "Nuclear speckles" "CAB034320: , HPA042745: " "unprognostic (6.92e-3)" "unprognostic (3.26e-3)" "unprognostic (1.28e-1)" "unprognostic (1.08e-1)" "unprognostic (1.92e-1)" "unprognostic (6.08e-2)" "unprognostic (1.41e-2)" "potential prognostic unfavorable (6.04e-4)" "unprognostic (5.27e-3)" "unprognostic (2.18e-2)" "validated prognostic unfavorable (3.29e-9)" "validated prognostic unfavorable (4.28e-5)" "unprognostic (2.42e-2)" "potential prognostic unfavorable (2.47e-5)" "unprognostic (1.32e-1)" "unprognostic (1.47e-3)" "unprognostic (3.15e-3)" "unprognostic (1.24e-1)" "unprognostic (1.96e-2)" "unprognostic (3.19e-2)" "unprognostic (8.82e-2)" "unprognostic (4.29e-3)" "unprognostic (8.20e-2)" "unprognostic (1.92e-1)" "unprognostic (5.85e-3)" "unprognostic (4.86e-3)" "unprognostic (7.18e-2)" "unprognostic (2.96e-1)" "unprognostic (1.59e-1)" "unprognostic (1.87e-3)" "unprognostic (2.12e-2)" S100A12 "CAAF1, CAGC, CGRP, ENRAGE, MRP6, p6" ENSG00000163221 "S100 calcium binding protein A12" P80511 1 153373711-153375621 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Antibiotic, Antimicrobial, Fungicide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "bone marrow: 3294.1" "Cell type enhanced" "Detected in some" "Esophageal apical cells: 1614.6;Monocyte progenitors: 542.6;monocytes: 884.8;Neutrophil progenitors: 4217.6;Neutrophils: 6920.4" "Cell type enriched" "Detected in single" 5 "leukocyte: 1.6" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 109.1" "Region enhanced" "Detected in many" "cerebral cortex: 7.2" "Group enriched" "Detected in many" 13 "classical monocyte: 1326.0;neutrophil: 1795.5" "Group enriched" "Detected in many" 13 "granulocytes: 1795.5;monocytes: 1326.0" "Group enriched" "Detected in some" 5 "cervical cancer: 3.9;head and neck cancer: 5.5;Leukemia: 2.0" "Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophils_2, Pituitary gland - Neutrophils, Skeletal muscle - Neutrophils, Spleen - Neutrophils_2, Stomach - Neutrophils, Thyroid gland - Neutrophils" "Region enhanced" "Detected in some" "cerebral cortex: 5.5" "HPA002881, CAB025872" Enhanced "Secreted to blood" Immunity NA NA 28500000 27000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 15: Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 1 "CAB025872: , HPA002881: " "unprognostic (7.88e-2)" "unprognostic (7.47e-2)" "unprognostic (1.51e-1)" "unprognostic (3.96e-1)" "unprognostic (6.57e-2)" "unprognostic (1.76e-2)" "unprognostic (1.01e-2)" "unprognostic (6.34e-2)" "unprognostic (1.91e-1)" "unprognostic (1.50e-1)" "unprognostic (8.12e-2)" "unprognostic (1.76e-2)" "unprognostic (9.30e-3)" "unprognostic (2.21e-2)" "unprognostic (2.14e-1)" "unprognostic (1.87e-1)" "unprognostic (1.24e-1)" "unprognostic (1.65e-1)" "unprognostic (1.54e-1)" "unprognostic (4.81e-2)" "unprognostic (9.43e-2)" "unprognostic (1.31e-1)" "potential prognostic unfavorable (5.10e-4)" "unprognostic (2.75e-1)" "unprognostic (7.91e-2)" S100A13 ENSG00000189171 "S100 calcium binding protein A13" Q99584 1 153618787-153631360 "Predicted intracellular proteins, Predicted secreted proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 743.3;Endometrial luminal cells: 463.0;Esophageal apical cells: 855.7;Gastric progenitor cells: 565.2;Hepatic stellate cells: 935.9;Leydig cells: 510.7" "Cell type enhanced" "Detected in many" "astrocyte: 60.9;endothelial cell: 75.1;fibroblast: 61.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 33.3" "Group enriched" "Detected in all" 5 "dendritic cells: 13.7;NK-cells: 33.3" "Low cancer specificity" "Detected in all" "Pancreas - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019592, CAB025494" Approved Approved "Nucleoplasm,Nucleoli,Plasma membrane,Cytosol" "Secreted in other tissues" Transport NA NA 7700 "Cluster 5: Non-specific - Cell proliferation" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 108: Fibroblasts - ECM organization" 7 "Plasma membrane, Cytosol" "Nucleoplasm, Nucleoli" "CAB025494: , HPA019592: " "unprognostic (7.22e-2)" "unprognostic (7.75e-2)" "unprognostic (7.57e-2)" "unprognostic (3.00e-1)" "unprognostic (9.57e-2)" "unprognostic (3.82e-2)" "unprognostic (6.11e-2)" "potential prognostic unfavorable (7.41e-5)" "unprognostic (1.99e-3)" "unprognostic (3.78e-1)" "potential prognostic unfavorable (3.98e-5)" "unprognostic (2.84e-1)" "unprognostic (5.10e-2)" "potential prognostic unfavorable (6.36e-4)" "unprognostic (4.08e-2)" "unprognostic (2.52e-1)" "unprognostic (5.62e-2)" "unprognostic (1.45e-1)" "potential prognostic unfavorable (5.10e-4)" "unprognostic (1.83e-1)" "unprognostic (1.21e-1)" "potential prognostic unfavorable (9.18e-4)" "unprognostic (3.08e-2)" "unprognostic (2.40e-3)" "potential prognostic unfavorable (3.30e-5)" "unprognostic (4.03e-1)" "unprognostic (1.27e-1)" "unprognostic (4.94e-3)" "unprognostic (1.48e-1)" "unprognostic (1.01e-2)" "unprognostic (5.10e-2)" S100A14 "BCMP84, S100A15" ENSG00000189334 "S100 calcium binding protein A14" Q9HCY8 1 153614255-153616986 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 3629.8;vagina: 1167.7" "Group enriched" "Detected in many" 7 "Esophageal apical cells: 56118.8;Esophageal suprabasal cells: 16151.8" "Cell type enriched" "Detected in single" 4 "astrocyte: 2.2" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 1115.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 1004.1" "Breast - Breast glandular cells, Colon - Colon enterocytes, Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Urothelial cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA027613 Enhanced Approved "Nuclear bodies,Plasma membrane,Cell Junctions,Cytosol" NA NA 560000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 27: Breast cancer - Unknown function" "Cluster 85: Squamous epithelial cells - Keratinization" 4 "Nuclear bodies, Plasma membrane, Cell Junctions, Cytosol" "HPA027613: " "unprognostic (1.42e-1)" "unprognostic (1.02e-1)" "unprognostic (5.89e-2)" "unprognostic (5.56e-2)" "unprognostic (1.91e-1)" "unprognostic (7.19e-2)" "unprognostic (9.23e-2)" "unprognostic (2.98e-2)" "unprognostic (2.12e-1)" "unprognostic (2.84e-2)" "unprognostic (6.39e-2)" "unprognostic (2.07e-2)" "unprognostic (9.40e-3)" "unprognostic (6.56e-2)" "unprognostic (1.53e-1)" "unprognostic (4.41e-1)" "potential prognostic unfavorable (2.61e-4)" "unprognostic (4.85e-2)" "unprognostic (2.97e-1)" "unprognostic (3.03e-3)" "unprognostic (4.89e-2)" "unprognostic (3.06e-1)" "unprognostic (1.51e-2)" "unprognostic (1.08e-2)" "unprognostic (3.06e-1)" "unprognostic (8.30e-2)" "unprognostic (1.92e-1)" "unprognostic (9.58e-2)" "unprognostic (1.20e-1)" S100A16 "DT1P1A7, MGC17528, S100F" ENSG00000188643 "S100 calcium binding protein A16" Q96FQ6 1 153606886-153613145 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 2382.1" "Group enriched" "Detected in many" 5 "Esophageal apical cells: 21739.8;Esophageal suprabasal cells: 8392.9" "Cell type enhanced" "Detected in many" "Bergmann glia: 38.2;endothelial cell: 52.1;oligodendrocyte precursor cell: 24.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Pituitary gland - Endothelial cells, Prostate - Urothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045841 Enhanced Approved "Plasma membrane,Cytosol" NA NA 270000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 44: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 85: Squamous epithelial cells - Keratinization" 1 Cytosol "Plasma membrane" "HPA045841: " "unprognostic (1.91e-1)" "unprognostic (1.48e-2)" "unprognostic (1.61e-1)" "unprognostic (1.69e-1)" "unprognostic (2.52e-1)" "unprognostic (1.40e-1)" "unprognostic (1.95e-1)" "unprognostic (4.94e-2)" "unprognostic (1.18e-1)" "unprognostic (2.23e-1)" "unprognostic (2.76e-3)" "potential prognostic unfavorable (4.71e-4)" "unprognostic (2.35e-1)" "potential prognostic unfavorable (4.86e-6)" "unprognostic (1.85e-2)" "potential prognostic unfavorable (6.60e-7)" "unprognostic (1.26e-2)" "unprognostic (2.02e-1)" "unprognostic (5.08e-3)" "unprognostic (5.31e-1)" "unprognostic (2.92e-1)" "potential prognostic unfavorable (3.11e-5)" "unprognostic (5.28e-2)" "unprognostic (3.02e-2)" "unprognostic (1.70e-2)" "unprognostic (2.06e-2)" "unprognostic (3.10e-1)" "unprognostic (2.42e-2)" "unprognostic (1.27e-1)" "unprognostic (1.09e-1)" "unprognostic (8.79e-2)" S100A2 "CAN19, S100L" ENSG00000196754 "S100 calcium binding protein A2" P29034 1 153561108-153567890 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 3547.5;urinary bladder: 1021.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 10840.8;Epididymal basal cells: 3107.6;Esophageal apical cells: 19225.2;Esophageal basal cells: 20239.3;Esophageal suprabasal cells: 32841.1;Suprabasal keratinocytes: 5197.5" "Cell type enriched" "Detected in some" 4 "astrocyte: 5.6" "Group enriched" "Detected in all" 8 "Bladder Urothelial Carcinoma (TCGA): 2907.7;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 5064.2;Head and Neck Squamous Cell Carcinoma (TCGA): 6939.4;Lung Squamous Cell Carcinoma (TCGA): 2517.4" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 10.2" "Lineage enriched" "Detected in many" 4 "granulocytes: 10.2" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 7682.4;head and neck cancer: 2632.4" "Breast - Breast myoepithelial cells, Minor Salivary Gland - Minor salivary gland basal cells, Skin - Hair cortex cells, Skin - Outer root sheath cells" "Not detected" "Not detected" "Region enriched" "Detected in single" 4 "spinal cord: 2.5" "CAB002600, CAB047340, HPA062451" Enhanced Approved "Nucleoplasm,Nucleoli,Plasma membrane,Cytosol" NA NA 89000 "Cluster 41: Basophils - Unknown function" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 39: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 39 "Nucleoplasm, Cytosol" "Nucleoli, Plasma membrane" "CAB002600: , CAB047340: , HPA062451: " "unprognostic (2.63e-3)" "unprognostic (5.15e-2)" "unprognostic (4.83e-2)" "unprognostic (7.96e-2)" "unprognostic (2.60e-2)" "unprognostic (2.48e-2)" "unprognostic (2.33e-1)" "unprognostic (3.64e-1)" "unprognostic (3.18e-1)" "unprognostic (7.96e-2)" "unprognostic (5.97e-2)" "potential prognostic unfavorable (6.73e-4)" "unprognostic (5.94e-2)" "unprognostic (1.04e-3)" "unprognostic (1.54e-2)" "unprognostic (3.79e-2)" "unprognostic (1.00e-3)" "unprognostic (2.82e-2)" "potential prognostic unfavorable (5.64e-4)" "unprognostic (2.46e-2)" "unprognostic (3.02e-1)" "potential prognostic unfavorable (3.73e-4)" "unprognostic (2.72e-3)" "unprognostic (3.49e-2)" "unprognostic (6.07e-2)" "unprognostic (7.01e-2)" "unprognostic (1.20e-1)" "unprognostic (2.27e-1)" "unprognostic (1.55e-1)" "unprognostic (1.98e-1)" "unprognostic (7.73e-2)" S100A3 S100E ENSG00000188015 "S100 calcium binding protein A3" P33764 1 153547329-153549258 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 98.8" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in all" 4 "Bladder Urothelial Carcinoma (TCGA): 107.5;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 37.7;Uterine Corpus Endometrial Carcinoma (TCGA): 41.7" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 9 "intermediate monocyte: 3.1;non-classical monocyte: 6.3;plasmacytoid DC: 7.5" "Group enriched" "Detected in many" 11 "dendritic cells: 7.5;monocytes: 6.3" "Low cancer specificity" "Detected in many" "Skin - Hair cortex cells, Skin - Inner root sheath cells" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 20.9" "HPA042674, HPA056140" Enhanced Enhanced "Golgi apparatus,Plasma membrane,Cytosol" NA NA 52000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 9: Skin - Hair follicle development" "Cluster 39: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 108: Fibroblasts - ECM organization" 21 Cytosol "Golgi apparatus, Plasma membrane" "HPA042674: , HPA056140: " "unprognostic (2.33e-1)" "unprognostic (1.15e-1)" "unprognostic (1.33e-1)" "unprognostic (3.19e-2)" "unprognostic (2.72e-2)" "unprognostic (3.55e-2)" "unprognostic (9.71e-2)" "unprognostic (1.35e-1)" "unprognostic (1.37e-2)" "unprognostic (2.32e-1)" "unprognostic (2.62e-1)" "unprognostic (1.26e-2)" "unprognostic (1.45e-2)" "unprognostic (1.74e-1)" "unprognostic (1.40e-1)" "unprognostic (1.84e-2)" "unprognostic (1.12e-1)" "unprognostic (6.99e-2)" "unprognostic (1.58e-2)" "unprognostic (6.17e-2)" "unprognostic (3.47e-2)" "unprognostic (3.73e-3)" "unprognostic (2.36e-2)" "unprognostic (1.46e-3)" "unprognostic (1.57e-1)" "unprognostic (6.74e-2)" "unprognostic (2.38e-1)" "unprognostic (9.15e-2)" "unprognostic (5.00e-1)" "unprognostic (4.38e-2)" "unprognostic (7.75e-2)" S100A4 "18A2, 42A, CAPL, FSP1, MTS1, P9KA, PEL98" ENSG00000196154 "S100 calcium binding protein A4" P26447 1 153543613-153550136 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 2003.6" "Cell type enhanced" "Detected in many" "cDC: 2551.9;Decidual stromal cells: 2841.5;Hofbauer cells: 2097.9;Mast cells: 1783.0;Megakaryocytes: 2874.5;Monocyte progenitors: 2526.5;monocytes: 3838.6;Neutrophils: 4487.0;Ocular epithelial cells: 8609.5" "Group enriched" "Detected in some" 5 "leukocyte: 363.0;vascular associated smooth muscle cell: 245.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Rhabdoid: 2211.4" "Breast - Fibroblasts, Kidney - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Spleen - Neutrophils_2, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 4 "spinal cord: 52.5" "CAB002618, HPA007973, CAB027387, CAB058698, CAB068227, CAB068228" Enhanced Supported Nucleoplasm,Cytosol "Secreted to blood" "No annotated function" NA NA 8100000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 30 Nucleoplasm Cytosol "CAB002618: , CAB027387: , CAB058698: , CAB068227: , CAB068228: , HPA007973: " "unprognostic (1.89e-2)" "unprognostic (5.45e-2)" "unprognostic (3.26e-1)" "unprognostic (2.51e-2)" "unprognostic (8.48e-2)" "unprognostic (2.56e-2)" "unprognostic (1.83e-3)" "unprognostic (2.14e-3)" "unprognostic (2.23e-3)" "unprognostic (1.05e-1)" "unprognostic (4.03e-1)" "unprognostic (3.00e-2)" "unprognostic (5.46e-2)" "unprognostic (1.27e-1)" "unprognostic (3.39e-1)" "unprognostic (8.29e-2)" "unprognostic (5.99e-2)" "unprognostic (1.59e-1)" "unprognostic (1.28e-1)" "unprognostic (3.81e-1)" "unprognostic (5.23e-2)" "unprognostic (1.61e-3)" "unprognostic (2.77e-3)" "unprognostic (4.08e-2)" "unprognostic (1.76e-2)" "potential prognostic favorable (5.66e-6)" "unprognostic (6.14e-2)" "unprognostic (1.47e-1)" "unprognostic (1.35e-1)" "unprognostic (5.50e-2)" "unprognostic (3.60e-1)" S100A5 S100D ENSG00000196420 "S100 calcium binding protein A5" P33763 1 153537147-153541765 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skin 1: 2.6;thyroid gland: 2.9" "Cell type enhanced" "Detected in some" "Epicardial cells: 2.3;Epididymal clear cells: 2.0;Extravillous trophoblasts: 12.1;Mast cells: 3.3;Ocular epithelial cells: 3.7;Paneth cells: 3.9;Urothelial cells: 5.8" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 25.0" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "dendritic cells: 2.5;granulocytes: 1.3;T-cells: 3.7" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 86 "olfactory bulb: 979.9" "Region enriched" "Detected in single" 15 "olfactory bulb: 12.3" HPA064184 Approved Nucleoplasm Yes NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 72: Kidney - Transmembrane transport" "Cluster 35: Non-specific - DNA binding" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 100: Stratified epithelial cells - Barrier functions" 8 Nucleoplasm "HPA064184: " "unprognostic (1.12e-1)" "unprognostic (1.72e-1)" "potential prognostic favorable (2.95e-4)" "unprognostic (1.05e-1)" "unprognostic (1.16e-2)" "unprognostic (4.93e-2)" "unprognostic (4.79e-1)" "unprognostic (1.64e-1)" "unprognostic (7.81e-2)" "unprognostic (1.13e-3)" "unprognostic (1.05e-1)" "unprognostic (1.35e-1)" "unprognostic (1.76e-1)" "unprognostic (1.07e-2)" "unprognostic (1.34e-2)" "unprognostic (1.56e-1)" "unprognostic (1.55e-1)" "unprognostic (4.27e-3)" "unprognostic (1.26e-1)" "unprognostic (3.53e-2)" S100A6 "2A9, CABP, CACY, PRA" ENSG00000197956 "S100 calcium binding protein A6" P06703 1 153534599-153536244 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 9120.5;Colonocytes: 21095.2;Decidual stromal cells: 9939.1;Endometrial secretory cells: 9533.5;Esophageal apical cells: 13496.6;Gastric progenitor cells: 11251.8;Goblet cells: 11783.0;Ocular epithelial cells: 11436.2;Respiratory secretory cells: 9486.3;Urothelial cells: 11837.5" "Cell type enhanced" "Detected in all" "leukocyte: 299.6;vascular associated smooth muscle cell: 612.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002601, HPA007575, CAB040549, CAB047354" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA 38000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 12: Non-specific - Vasculature" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 27 "Plasma membrane, Cytosol" "CAB002601: , CAB040549: , CAB047354: , HPA007575: " "unprognostic (2.02e-1)" "unprognostic (2.54e-2)" "unprognostic (1.00e-1)" "unprognostic (1.97e-1)" "unprognostic (3.00e-1)" "unprognostic (3.71e-1)" "unprognostic (7.02e-2)" "unprognostic (1.98e-2)" "unprognostic (1.08e-1)" "unprognostic (5.44e-2)" "unprognostic (1.66e-3)" "unprognostic (1.44e-3)" "unprognostic (1.93e-1)" "potential prognostic unfavorable (5.14e-4)" "unprognostic (1.40e-1)" "unprognostic (9.10e-3)" "unprognostic (1.53e-2)" "unprognostic (1.34e-1)" "unprognostic (5.98e-2)" "unprognostic (1.35e-1)" "unprognostic (2.72e-1)" "unprognostic (4.93e-3)" "unprognostic (1.82e-1)" "unprognostic (2.02e-1)" "unprognostic (6.67e-2)" "unprognostic (9.45e-2)" "unprognostic (4.79e-2)" "unprognostic (1.80e-1)" "unprognostic (1.21e-1)" "unprognostic (1.97e-2)" "unprognostic (3.66e-2)" S100A7 "PSOR1, S100A7c" ENSG00000143556 "S100 calcium binding protein A7" P31151 1 153457744-153460651 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 1900.9;esophagus: 1264.3;lymphoid tissue: 1158.8;vagina: 1368.9" "Group enriched" "Detected in some" 4 "Esophageal apical cells: 11223.9;Esophageal suprabasal cells: 5422.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 3396.2;Skin Cutaneous Melanoma (TCGA): 1553.0" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 8 "head and neck cancer: 469.5" "CAB001453, HPA006997, CAB033766" Enhanced Supported Cytosol "Secreted in other tissues" "No annotated function" NA NA 42000000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 2: Neurons - Nucleosome" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 37 Cytosol "CAB001453: , CAB033766: , HPA006997: " "unprognostic (1.45e-1)" "unprognostic (2.91e-1)" "unprognostic (4.30e-1)" "unprognostic (1.19e-1)" "unprognostic (1.61e-1)" "unprognostic (5.94e-2)" "unprognostic (1.05e-1)" "unprognostic (7.55e-3)" "unprognostic (6.24e-1)" "unprognostic (2.97e-2)" "unprognostic (2.78e-1)" "unprognostic (8.23e-2)" "unprognostic (4.53e-2)" "unprognostic (8.79e-2)" "unprognostic (1.74e-1)" "unprognostic (1.52e-1)" "unprognostic (1.41e-3)" "unprognostic (1.57e-2)" "unprognostic (2.09e-2)" "unprognostic (2.05e-1)" "unprognostic (2.45e-1)" "unprognostic (1.56e-1)" "unprognostic (1.43e-1)" S100A7A "S100A15, S100A7f, S100A7L1" ENSG00000184330 "S100 calcium binding protein A7A" Q86SG5 1 153416520-153423222 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 34 "cervix: 6.5;esophagus: 5.7;lymphoid tissue: 5.5;skin 1: 2.3;vagina: 2.6" "Group enriched" "Detected in some" 5 "Esophageal apical cells: 27.6;Esophageal suprabasal cells: 21.8" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Head and Neck Squamous Cell Carcinoma (TCGA): 39.5;Skin Cutaneous Melanoma (TCGA): 19.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 9 "head and neck cancer: 6.4" "Testis - Late spermatids" HPA006997 Supported Uncertain Cytosol NA NA 30000000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 27 Cytosol "HPA006997: " "unprognostic (3.73e-1)" "unprognostic (3.28e-1)" "unprognostic (8.14e-2)" "unprognostic (4.57e-2)" "unprognostic (2.14e-1)" "unprognostic (1.88e-2)" "unprognostic (1.41e-1)" S100A8 "60B8AG, CAGA, CFAG, CGLA, MRP-8, MRP8, P8, S100-A8" ENSG00000143546 "S100 calcium binding protein A8" P05109 1 153390032-153391073 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Autophagy, Chemotaxis, Immunity, Inflammatory response, Innate immunity" Antimicrobial "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 33387.3;cervix: 14477.9;esophagus: 36526.2;vagina: 16753.2" "Group enriched" "Detected in many" 5 "Esophageal apical cells: 442326.6;Esophageal suprabasal cells: 118514.7" "Cell type enriched" "Detected in single" 61 "leukocyte: 38.2" "Cancer enhanced" "Detected in all" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 10785.2;Head and Neck Squamous Cell Carcinoma (TCGA): 12921.4" "Region enhanced" "Detected in all" "cerebral cortex: 66.1" "Group enriched" "Detected in all" 9 "classical monocyte: 26966.7;neutrophil: 53446.0" "Group enriched" "Detected in all" 9 "granulocytes: 53446.0;monocytes: 26966.7" "Group enriched" "Detected in many" 6 "breast cancer: 333.1;cervical cancer: 581.7;head and neck cancer: 730.8" "Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophils_2, Pituitary gland - Neutrophils, Skeletal muscle - Neutrophils, Spleen - Neutrophils_2, Stomach - Neutrophils, Thyroid gland - Neutrophils" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB002791, HPA024372" Enhanced Supported "Intermediate filaments,Cytosol" "Secreted to blood" Immunity NA NA 10900000 300000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 28 "Intermediate filaments" Cytosol "CAB002791: , HPA024372: " "unprognostic (2.27e-1)" "unprognostic (2.23e-1)" "unprognostic (1.06e-1)" "unprognostic (6.86e-2)" "unprognostic (3.03e-1)" "unprognostic (1.81e-1)" "potential prognostic unfavorable (9.35e-4)" "unprognostic (5.33e-2)" "unprognostic (1.02e-2)" "unprognostic (4.32e-1)" "unprognostic (1.03e-2)" "unprognostic (5.08e-2)" "unprognostic (5.07e-2)" "unprognostic (7.11e-2)" "unprognostic (9.14e-2)" "unprognostic (2.05e-2)" "unprognostic (5.75e-2)" "unprognostic (3.40e-1)" "unprognostic (1.31e-3)" "unprognostic (2.98e-1)" "unprognostic (3.31e-2)" "unprognostic (1.98e-2)" "unprognostic (5.58e-2)" "unprognostic (3.05e-2)" "unprognostic (8.69e-2)" "unprognostic (1.32e-1)" "unprognostic (2.19e-1)" "unprognostic (1.45e-1)" "unprognostic (1.99e-1)" "unprognostic (2.79e-2)" "unprognostic (1.86e-1)" S100A9 "60B8AG, CAGB, CFAG, CGLB, LIAG, MAC387, MIF, MRP-14, MRP14, NIF, P14, S100-A9" ENSG00000163220 "S100 calcium binding protein A9" P06702 1 153357854-153361023 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Autophagy, Chemotaxis, Immunity, Inflammatory response, Innate immunity" "Antimicrobial, Antioxidant" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 30401.1;cervix: 13503.3;esophagus: 30106.4;vagina: 13777.0" "Cell type enriched" "Detected in many" 4 "Esophageal apical cells: 540718.9" "Cell type enriched" "Detected in single" 57 "leukocyte: 20.6" "Cancer enhanced" "Detected in all" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 9596.7;Head and Neck Squamous Cell Carcinoma (TCGA): 12365.7" "Region enhanced" "Detected in all" "cerebral cortex: 97.1" "Group enriched" "Detected in all" 6 "classical monocyte: 24645.2;neutrophil: 33874.3" "Group enriched" "Detected in all" 6 "granulocytes: 33874.3;monocytes: 24645.2" "Cancer enhanced" "Detected in many" "breast cancer: 536.0;head and neck cancer: 1157.4" "Colon - Neutrophils, Kidney - Macrophages, Liver - Neutrophils, Lung - Neutrophils_2, Pituitary gland - Neutrophils, Prostate - Macrophages, Spleen - Neutrophils_2, Thyroid gland - Neutrophils" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA004193, CAB009441, CAB080262" Enhanced Supported "Plasma membrane,Intermediate filaments,Cytosol" "Secreted to blood" Immunity NA NA 10600000 1100000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 44 "Plasma membrane, Intermediate filaments, Cytosol" "CAB009441: , CAB080262: , HPA004193: " "unprognostic (8.79e-2)" "unprognostic (1.28e-1)" "unprognostic (1.23e-1)" "unprognostic (1.50e-2)" "unprognostic (3.50e-1)" "unprognostic (4.57e-1)" "potential prognostic unfavorable (2.06e-4)" "unprognostic (3.56e-2)" "unprognostic (4.25e-3)" "unprognostic (8.25e-2)" "unprognostic (5.24e-2)" "unprognostic (3.07e-1)" "unprognostic (2.03e-1)" "potential prognostic unfavorable (6.94e-6)" "unprognostic (1.29e-1)" "unprognostic (6.18e-3)" "unprognostic (2.51e-1)" "unprognostic (1.85e-1)" "potential prognostic unfavorable (2.89e-4)" "unprognostic (1.78e-1)" "unprognostic (1.59e-1)" "unprognostic (8.06e-3)" "unprognostic (1.70e-3)" "unprognostic (3.30e-2)" "unprognostic (5.43e-2)" "unprognostic (3.16e-1)" "unprognostic (2.19e-1)" "unprognostic (8.19e-2)" "unprognostic (1.18e-1)" "unprognostic (2.92e-2)" "unprognostic (1.68e-1)" S100B S100beta ENSG00000160307 "S100 calcium binding protein B" P04271 21 46598604-46605208 "Cancer-related genes, Candidate cardiovascular disease genes, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 4757.1" "Cell type enhanced" "Detected in many" "Astrocytes: 256.4;Bergmann glia: 670.9;Breast myoepithelial cells: 169.6;cDC: 159.1;Melanocytes: 211.1;Oligodendrocyte progenitor cells: 203.1;Oligodendrocytes: 513.3;Retinal pigment epithelial cells: 306.9;Schwann cells: 1448.6" "Cell type enhanced" "Detected in all" "Bergmann glia: 839.6;oligodendrocyte: 1025.9" "Group enriched" "Detected in many" 64 "Glioblastoma Multiforme (TCGA): 1024.8;Skin Cutaneous Melanoma (TCGA): 1223.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 361.7" "Lineage enriched" "Detected in all" 6 "T-cells: 361.7" "Cancer enriched" "Detected in many" 8 "skin cancer: 980.5" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal medulla cells, Breast - Adipocytes (Breast), Colon - Enteric glia cells, Minor Salivary Gland - Fibroblasts, Pituitary gland - Undifferentiated cells (Pituitary gland), Spleen - Macrophages, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000073, HPA015768, CAB078196" Enhanced Supported Approved "Nucleoplasm,Vesicles,Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Basal body,Cytosol" "Secreted - unknown location" "Cell adhesion" Yes NA 140000 "Cluster 24: Non-specific - Transcription" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 69: Skin cancer - ECM organization" "Cluster 82: Dendritic cells - Antigen presentation" 56 "Vesicles, Primary cilium, Cytosol" "Nucleoplasm, Microtubules, Cytokinetic bridge, Mitotic spindle, Basal body" "CAB000073: , CAB078196: , HPA015768: " "unprognostic (3.93e-1)" "unprognostic (1.37e-3)" "unprognostic (5.60e-2)" "unprognostic (1.46e-2)" "unprognostic (6.70e-3)" "unprognostic (4.80e-2)" "unprognostic (1.22e-3)" "potential prognostic unfavorable (4.68e-6)" "unprognostic (1.28e-2)" "unprognostic (3.93e-2)" "unprognostic (4.77e-2)" "unprognostic (4.81e-3)" "unprognostic (6.77e-2)" "unprognostic (1.35e-1)" "unprognostic (6.50e-3)" "unprognostic (1.14e-1)" "unprognostic (7.40e-2)" "unprognostic (3.95e-2)" "unprognostic (3.53e-1)" "unprognostic (2.40e-1)" "unprognostic (2.82e-3)" "unprognostic (3.41e-2)" "unprognostic (1.33e-2)" "unprognostic (2.01e-1)" "unprognostic (4.23e-1)" "unprognostic (3.14e-1)" "unprognostic (2.74e-2)" "unprognostic (6.83e-2)" "unprognostic (1.10e-1)" "unprognostic (1.03e-1)" S100G "CABP1, CABP9K, CALB3" ENSG00000169906 "S100 calcium binding protein G" P29377 X 16650158-16654670 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 202 "intestine: 223.9" "Cell type enhanced" "Detected in some" "Adipocytes: 2.1;Cardiomyocytes: 3.4;Epicardial cells: 2.3;Fibro-adipogenic progenitors: 1.5;Mast cells: 1.2;Respiratory deuterosomal cells: 1.0;Retinal ganglion cells: 3.9" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Breast Invasive Carcinoma (TCGA): 11.6;Kidney Renal Clear Cell Carcinoma (TCGA): 3.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "pons and medulla: 1.1" "Low region specificity" "Detected in some" "CAB017688, HPA028920, HPA055873" Enhanced Approved Cytosol NA NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 25: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" Cytosol "CAB017688: , HPA028920: , HPA055873: " "unprognostic (1.73e-2)" "unprognostic (9.31e-1)" "unprognostic (1.83e-1)" "potential prognostic unfavorable (1.55e-5)" "unprognostic (5.98e-1)" "unprognostic (1.84e-1)" "unprognostic (1.31e-1)" S100P ENSG00000163993 "S100 calcium binding protein P" P25815 4 6693878-6697170 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 1330.4;esophagus: 584.2;placenta: 445.8;stomach 1: 1640.9;urinary bladder: 1656.2" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 2056.3;Esophageal apical cells: 9537.5;Foveolar cells: 4417.9;Gastric progenitor cells: 1568.8;Neutrophils: 1944.7;Prostatic club cells: 3278.5;Prostatic hillock cells: 2245.5;Respiratory secretory cells: 1244.7;Syncytiotrophoblasts: 3446.9;Urothelial cells: 6283.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 2315.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 46 "basophil: 1796.7;eosinophil: 839.7;neutrophil: 2984.9" "Lineage enriched" "Detected in many" 73 "granulocytes: 2984.9" "Low cancer specificity" "Detected in all" "Adipose visceral - Neutrophils, Colon - Colon enterocytes, Heart muscle - Neutrophils, Liver - Neutrophils, Pituitary gland - Neutrophils, Prostate - Urothelial cells, Skeletal muscle - Neutrophils, Spleen - Neutrophils_2, Stomach - Gastric mucous cells, Testis - Late spermatids, Thyroid gland - Neutrophils" "HPA019502, HPA075251" Enhanced Supported Nucleoplasm NA NA 3800000 "Cluster 35: Neutrophils - Protein binding" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 12: Non-specific - Vasculature" "Cluster 7: Liver cancer - Metabolism" "Cluster 84: Apical squamous epithelium - Cornification" 32 Nucleoplasm "HPA019502: , HPA075251: " "unprognostic (1.24e-2)" "unprognostic (1.31e-1)" "unprognostic (2.24e-1)" "unprognostic (1.23e-1)" "unprognostic (3.65e-2)" "unprognostic (2.01e-1)" "unprognostic (2.43e-1)" "unprognostic (6.96e-2)" "unprognostic (2.58e-1)" "unprognostic (1.66e-1)" "unprognostic (1.44e-1)" "unprognostic (1.16e-3)" "unprognostic (3.78e-2)" "potential prognostic unfavorable (5.76e-4)" "unprognostic (1.55e-1)" "unprognostic (1.97e-1)" "unprognostic (7.75e-2)" "unprognostic (1.24e-1)" "unprognostic (1.54e-1)" "potential prognostic unfavorable (3.46e-4)" "unprognostic (1.78e-1)" "unprognostic (2.47e-2)" "unprognostic (8.13e-2)" "unprognostic (1.11e-1)" "unprognostic (5.01e-2)" "unprognostic (6.25e-2)" "unprognostic (1.77e-1)" "unprognostic (1.65e-1)" S100PBP "FLJ12903, S100PBPR" ENSG00000116497 "S100P binding protein" Q96BU1 1 32816767-32858875 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 211.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027242, HPA027328" Approved Supported "Nuclear speckles,Cytosol" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 39: Testis - Nuclear processes" "Cluster 25: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 4 "Nuclear speckles" Cytosol "HPA027242: , HPA027328: " "unprognostic (4.12e-3)" "unprognostic (2.58e-1)" "unprognostic (7.65e-3)" "unprognostic (1.93e-1)" "unprognostic (2.83e-1)" "unprognostic (1.08e-1)" "unprognostic (5.11e-2)" "unprognostic (9.26e-3)" "unprognostic (1.84e-3)" "unprognostic (8.45e-2)" "unprognostic (6.00e-2)" "unprognostic (7.66e-2)" "unprognostic (4.03e-2)" "potential prognostic unfavorable (2.69e-6)" "unprognostic (1.10e-1)" "unprognostic (1.21e-1)" "unprognostic (9.57e-2)" "unprognostic (1.77e-1)" "unprognostic (8.46e-2)" "unprognostic (2.88e-1)" "unprognostic (4.04e-3)" "unprognostic (3.34e-1)" "potential prognostic unfavorable (7.36e-4)" "unprognostic (3.83e-3)" "unprognostic (4.79e-2)" "unprognostic (4.83e-3)" "unprognostic (1.21e-2)" "unprognostic (2.46e-1)" "unprognostic (1.49e-1)" "unprognostic (2.74e-2)" "unprognostic (1.48e-1)" S100Z "Gm625, S100-zeta" ENSG00000171643 "S100 calcium binding protein Z" Q8WXG8 5 76850001-76921650 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 2.2;lymphoid tissue: 2.9" "Cell type enhanced" "Detected in many" "cDC: 45.0;Hematopoietic stem cells: 71.8;Hofbauer cells: 32.8;Macrophages: 35.6;Microglia: 224.3;Monocyte progenitors: 62.4;monocytes: 81.6;Neutrophils: 68.0;Oocytes: 59.9;Thymocytes: 197.3" "Cell type enriched" "Detected in many" 4 "central nervous system macrophage: 257.6" "Cancer enhanced" "Detected in single" "Testicular Germ Cell Tumor (TCGA): 3.1" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "classical monocyte: 35.1;eosinophil: 31.9;intermediate monocyte: 34.0;myeloid DC: 19.5;neutrophil: 11.9;non-classical monocyte: 39.7" "Group enriched" "Detected in many" 6 "dendritic cells: 19.5;granulocytes: 31.9;monocytes: 39.7" "Group enriched" "Detected in some" 6 "Leukemia: 5.4;lymphoma: 17.0" "Region enriched" "Detected in single" 5 "olfactory bulb: 1.3" "Low region specificity" "Detected in all" HPA051929 Approved Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 11 "Centrosome, Cytosol" Nucleoplasm "HPA051929: " "unprognostic (2.32e-2)" "unprognostic (4.29e-2)" "unprognostic (2.42e-1)" S1PR1 "CD363, D1S3362, edg-1, EDG1" ENSG00000170989 "Sphingosine-1-phosphate receptor 1" P21453 1 101236865-101243713 "Cancer-related genes, CD markers, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "Angiogenesis, Chemotaxis" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 40.7;B-cells: 19.9;Bergmann glia: 71.3;Granulosa cells: 22.7;Hofbauer cells: 28.1;Innate lymphoid cells: 23.5;Lymphatic endothelial cells: 102.1;Müller glia: 36.6;NK-cells: 20.7;Thymocytes: 20.3;Vascular endothelial cells: 164.5" "Group enriched" "Detected in some" 6 "astrocyte: 43.8;Bergmann glia: 82.6;endothelial cell: 85.0;leukocyte: 21.3" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 58.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 1252.2" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Minor Salivary Gland - Endothelial cells, Pancreas - Endothelial cells, Pituitary gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010104, HPA075568" Supported Supported Vesicles No NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 19: Astrocytes - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 56 Vesicles "CAB010104: , HPA075568: " "unprognostic (1.40e-1)" "unprognostic (2.82e-1)" "unprognostic (7.69e-2)" "unprognostic (1.55e-1)" "unprognostic (3.32e-2)" "unprognostic (2.60e-2)" "unprognostic (3.97e-1)" "unprognostic (4.16e-3)" "unprognostic (1.27e-3)" "unprognostic (1.87e-1)" "validated prognostic favorable (1.94e-9)" "validated prognostic favorable (6.68e-4)" "unprognostic (1.38e-2)" "unprognostic (4.46e-3)" "unprognostic (1.04e-2)" "unprognostic (2.21e-2)" "unprognostic (2.02e-1)" "unprognostic (3.68e-2)" "unprognostic (9.71e-2)" "unprognostic (2.80e-1)" "unprognostic (1.46e-1)" "unprognostic (1.09e-1)" "unprognostic (3.17e-1)" "unprognostic (1.67e-1)" "unprognostic (6.40e-2)" "unprognostic (3.43e-2)" "unprognostic (1.56e-2)" "unprognostic (4.92e-2)" "unprognostic (8.75e-2)" "unprognostic (1.53e-1)" "unprognostic (4.28e-1)" S1PR2 "AGR16, DFNB68, EDG5, Gpcr13, H218" ENSG00000267534 "Sphingosine-1-phosphate receptor 2" O95136 19 10221433-10231331 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 5 "Late spermatids: 111.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 44.9" "Group enriched" "Detected in many" 8 "granulocytes: 44.9;T-cells: 12.4" "Cancer enhanced" "Detected in many" "lymphoma: 30.8" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Prostate - Fibroblasts, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA014255, HPA014307" Approved Uncertain "Nuclear speckles,Golgi apparatus" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 6: Non-specific - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" "Golgi apparatus" "Nuclear speckles" "HPA014255: , HPA014307: " "unprognostic (9.87e-3)" "unprognostic (2.29e-2)" "potential prognostic favorable (3.87e-5)" "unprognostic (4.14e-1)" "unprognostic (1.22e-1)" "unprognostic (1.51e-1)" "unprognostic (4.09e-2)" "unprognostic (8.16e-2)" "potential prognostic favorable (2.29e-4)" "unprognostic (3.50e-2)" "potential prognostic unfavorable (7.84e-5)" "unprognostic (1.50e-1)" "unprognostic (1.24e-3)" "unprognostic (6.46e-2)" "unprognostic (9.04e-2)" "unprognostic (1.20e-1)" "unprognostic (3.53e-3)" "unprognostic (3.34e-2)" "unprognostic (1.66e-1)" "unprognostic (2.68e-1)" "unprognostic (9.06e-2)" "unprognostic (4.45e-2)" "unprognostic (2.88e-1)" "unprognostic (2.99e-2)" "unprognostic (2.61e-1)" "unprognostic (1.32e-1)" "unprognostic (2.63e-1)" "unprognostic (1.41e-2)" "unprognostic (4.03e-2)" "unprognostic (3.76e-1)" "unprognostic (1.75e-1)" S1PR3 "bA791O21.3, C9orf108, C9orf47, EDG-3, EDG3, FLJ37523" ENSG00000213694 "Sphingosine-1-phosphate receptor 3" Q99500 9 88990863-89005155 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 59.3" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 22.1;Cytotrophoblasts: 26.2;Decidual stromal cells: 33.4;Endometrial stromal cells: 59.6;Ependymal cells: 21.0;Epicardial cells: 22.7;Fibroblasts: 37.6;Hepatic stellate cells: 25.8;Myosatellite cells: 28.8;Pericytes: 52.9;Schwann cells: 29.1;Smooth muscle cells: 45.3;Vascular smooth muscle cells: 64.1" "Group enriched" "Detected in many" 4 "ependymal cell: 26.5;fibroblast: 31.0;pericyte: 89.9;vascular associated smooth muscle cell: 62.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 18 "classical monocyte: 7.0" "Lineage enriched" "Detected in single" 18 "monocytes: 7.0" "Low cancer specificity" "Detected in many" "Lung - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 3 "unprognostic (1.95e-1)" "unprognostic (6.73e-2)" "unprognostic (2.18e-3)" "unprognostic (3.46e-1)" "unprognostic (5.54e-3)" "unprognostic (2.07e-2)" "unprognostic (2.05e-1)" "unprognostic (1.24e-2)" "unprognostic (9.79e-2)" "unprognostic (3.84e-2)" "unprognostic (9.13e-2)" "potential prognostic favorable (6.05e-4)" "unprognostic (3.90e-3)" "unprognostic (4.40e-2)" "unprognostic (5.80e-2)" "unprognostic (1.89e-1)" "potential prognostic unfavorable (6.85e-5)" "unprognostic (5.59e-2)" "unprognostic (1.15e-2)" "unprognostic (9.00e-2)" "unprognostic (1.91e-2)" "unprognostic (7.97e-2)" "unprognostic (2.26e-1)" "unprognostic (6.77e-2)" "unprognostic (2.96e-2)" "unprognostic (8.90e-2)" "unprognostic (3.50e-2)" "unprognostic (2.65e-2)" "unprognostic (2.05e-2)" "unprognostic (3.70e-2)" "unprognostic (8.47e-2)" S1PR4 EDG6 ENSG00000125910 "Sphingosine-1-phosphate receptor 4" O95977 19 3172346-3180332 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 18.5;lymphoid tissue: 58.6" "Cell type enhanced" "Detected in some" "B-cells: 38.3;Hematopoietic stem cells: 44.2;Megakaryocyte-Erythroid progenitors: 46.9;Monocyte progenitors: 33.6;monocytes: 34.7;Neutrophil progenitors: 88.5;Neutrophils: 290.9;NK-cells: 57.9;pDCs: 27.7;Plasma cells: 26.0;T-cells: 49.7" "Cell type enriched" "Detected in some" 9 "leukocyte: 35.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 13 "Leukemia: 45.8;lymphoma: 35.0;Myeloma: 24.7" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Minor Salivary Gland - Macrophages, Prostate - T-cells, Spleen - Neutrophils_2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA060601, HPA067232" Supported Mitochondria NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 6: Leukemia - Signal transduction" "Cluster 24: Neutrophils - Innate immunity signal integration" 87 Mitochondria "HPA060601: , HPA067232: " "unprognostic (1.77e-1)" "unprognostic (3.47e-3)" "unprognostic (1.61e-2)" "potential prognostic favorable (1.77e-6)" "unprognostic (5.94e-2)" "unprognostic (1.03e-1)" "unprognostic (1.42e-3)" "potential prognostic favorable (4.92e-7)" "unprognostic (1.98e-2)" "unprognostic (3.57e-1)" "unprognostic (2.30e-2)" "unprognostic (4.27e-3)" "unprognostic (1.43e-1)" "potential prognostic favorable (8.90e-4)" "unprognostic (1.86e-1)" "unprognostic (1.93e-2)" "unprognostic (9.20e-2)" "unprognostic (6.66e-3)" "unprognostic (1.26e-2)" "unprognostic (2.49e-1)" "unprognostic (1.25e-1)" "unprognostic (6.72e-2)" "unprognostic (2.02e-2)" "unprognostic (1.07e-1)" "unprognostic (8.20e-3)" "unprognostic (2.78e-1)" "unprognostic (2.23e-2)" "unprognostic (1.32e-1)" "unprognostic (1.54e-1)" S1PR5 "Edg-8, EDG8" ENSG00000180739 "Sphingosine-1-phosphate receptor 5" Q9H228 19 10512742-10517931 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 48.4" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 12.0;Esophageal basal cells: 23.3;NK-cells: 81.7;Oligodendrocytes: 25.2;Prostatic hillock cells: 11.4;Retinal pigment epithelial cells: 8.5;Submucosal glandular cells: 12.1;T-cells: 10.8" "Group enriched" "Detected in some" 6 "leukocyte: 42.3;oligodendrocyte: 33.9" "Group enriched" "Detected in many" 5 "Bladder Urothelial Carcinoma (TCGA): 14.6;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 29.6;Head and Neck Squamous Cell Carcinoma (TCGA): 16.8;Lung Squamous Cell Carcinoma (TCGA): 15.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 300.0;MAIT T-cell: 185.0;memory CD8 T-cell: 144.8;naive CD8 T-cell: 109.2" "Lineage enriched" "Detected in many" 7 "T-cells: 300.0" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Skin - Keratinocyte (other), Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029683 Enhanced NA NA "Cluster 1: T-cells - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 2 "HPA029683: " "unprognostic (1.06e-1)" "unprognostic (2.96e-2)" "unprognostic (1.59e-1)" "unprognostic (6.18e-2)" "unprognostic (3.11e-1)" "unprognostic (1.05e-1)" "unprognostic (7.93e-3)" "unprognostic (7.22e-3)" "unprognostic (1.95e-3)" "unprognostic (9.52e-2)" "unprognostic (1.45e-1)" "unprognostic (2.96e-1)" "potential prognostic unfavorable (4.06e-4)" "unprognostic (2.14e-1)" "unprognostic (1.20e-1)" "unprognostic (2.14e-2)" "unprognostic (7.67e-2)" "unprognostic (1.29e-3)" SAA1 "PIG4, SAA, TP53I4" ENSG00000173432 "Serum amyloid A1" P0DJI8 11 18266260-18269977 "Disease related genes, Predicted secreted proteins" "Acute phase" Heparin-binding Amyloidosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 19 "liver: 54032.7" "Cell type enriched" "Detected in many" 13 "Hepatocytes: 25740.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 1987.6" "Group enriched" "Detected in many" 5 "choroid plexus: 3.7;pons: 8.3;thalamus: 14.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 445.5" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Macrophages, Minor Salivary Gland - Minor salivary glandular cells" "Secreted to blood" "Acute phase" NA NA 300000000 10000000000 "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 1 "unprognostic (4.98e-2)" "unprognostic (1.91e-3)" "unprognostic (3.15e-2)" "unprognostic (6.97e-2)" "unprognostic (2.45e-1)" "unprognostic (1.76e-1)" "unprognostic (1.90e-3)" "unprognostic (1.52e-3)" "unprognostic (2.53e-2)" "unprognostic (3.80e-2)" "validated prognostic unfavorable (1.81e-10)" "validated prognostic unfavorable (6.77e-5)" "unprognostic (3.70e-2)" "unprognostic (3.25e-2)" "potential prognostic favorable (1.67e-4)" "unprognostic (7.29e-2)" "unprognostic (7.19e-3)" "unprognostic (2.22e-1)" "unprognostic (4.30e-3)" "unprognostic (1.33e-3)" "unprognostic (2.37e-1)" "unprognostic (1.43e-1)" "unprognostic (3.42e-2)" "unprognostic (6.93e-2)" "unprognostic (4.86e-2)" "unprognostic (2.19e-1)" "unprognostic (2.96e-1)" "unprognostic (1.81e-2)" "unprognostic (7.49e-2)" "unprognostic (2.23e-2)" "unprognostic (2.92e-1)" SAA2 ENSG00000134339 "Serum amyloid A2" P0DJI9 11 18239223-18248668 "Disease related genes, Predicted secreted proteins" "Acute phase" Amyloidosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 19 "liver: 31118.2" "Cell type enriched" "Detected in many" 11 "Hepatocytes: 15523.7" "Low cell type specificity" "Detected in some" "Cancer enriched" "Detected in many" 19 "Liver Hepatocellular Carcinoma (TCGA): 1437.3" "Group enriched" "Detected in all" 4 "pons: 17.8;thalamus: 22.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 394.0" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Macrophages, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids" "Secreted to blood" "Acute phase" NA NA 50000000 9900000000 "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 4 "potential prognostic unfavorable (2.89e-4)" "unprognostic (6.58e-3)" "unprognostic (1.28e-3)" "unprognostic (6.61e-2)" "unprognostic (2.48e-1)" "unprognostic (2.31e-1)" "potential prognostic unfavorable (6.28e-4)" "unprognostic (7.71e-3)" "unprognostic (3.11e-2)" "unprognostic (3.27e-1)" "validated prognostic unfavorable (1.77e-10)" "validated prognostic unfavorable (2.44e-4)" "unprognostic (1.91e-1)" "unprognostic (5.85e-2)" "potential prognostic favorable (3.69e-4)" "unprognostic (9.49e-2)" "unprognostic (3.72e-2)" "unprognostic (6.88e-2)" "unprognostic (6.44e-2)" "unprognostic (1.77e-2)" "unprognostic (1.54e-1)" "unprognostic (3.18e-2)" "unprognostic (1.00e-2)" "unprognostic (9.51e-2)" "unprognostic (1.29e-1)" "unprognostic (2.15e-1)" "unprognostic (1.22e-1)" "unprognostic (5.40e-2)" "unprognostic (1.21e-1)" "unprognostic (2.18e-1)" SAA2-SAA4 ENSG00000255071 "SAA2-SAA4 readthrough" 11 18231423-18248635 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 4 "liver: 95.6" "Cell type enhanced" "Detected in some" "Endometrial secretory cells: 32.1;Hepatocytes: 230.7;Salivary acinar cells: 47.7;Salivary basal cells: 38.9;Salivary ionocytes: 49.2;Salivary myoepithelial cells: 47.5;Submucosal glandular cells: 59.7;Thymic myoid cells: 176.8" "Cancer enriched" "Detected in many" 4 "Liver Hepatocellular Carcinoma (TCGA): 16.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 5.4;head and neck cancer: 11.6" HPA060139 Uncertain NA NA "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" "HPA060139: " "unprognostic (1.28e-3)" "unprognostic (3.96e-2)" "potential prognostic unfavorable (3.42e-4)" "unprognostic (4.72e-2)" "validated prognostic unfavorable (2.71e-8)" "validated prognostic unfavorable (4.66e-5)" "unprognostic (5.70e-2)" "unprognostic (6.17e-2)" "unprognostic (1.84e-1)" "unprognostic (2.85e-3)" "unprognostic (1.46e-1)" "unprognostic (7.17e-3)" "unprognostic (1.45e-1)" "unprognostic (3.23e-2)" "unprognostic (3.08e-3)" "unprognostic (1.53e-1)" "unprognostic (6.44e-3)" SAA4 "C-SAA, CSAA" ENSG00000148965 "Serum amyloid A4, constitutive" P35542 11 18231355-18236802 "Plasma proteins, Predicted secreted proteins" "Acute phase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 140 "liver: 2067.9" "Cell type enriched" "Detected in some" 37 "Hepatocytes: 1879.3" "Low cell type specificity" "Detected in single" "Cancer enriched" "Detected in many" 91 "Liver Hepatocellular Carcinoma (TCGA): 505.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 4.4;head and neck cancer: 6.3;liver cancer: 5.5" "Adipose visceral - Adipocytes (Visceral), Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "CAB026061, HPA060139" Supported "Secreted to blood" "Acute phase" NA NA 65000000000 6800000000 "Cluster 53: Liver - Plasma proteins" "Cluster 18: Liver cancer - Metabolism" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 2 "CAB026061: , HPA060139: " "unprognostic (3.97e-3)" "unprognostic (7.67e-3)" "unprognostic (1.04e-1)" "unprognostic (2.10e-1)" "unprognostic (1.39e-1)" "unprognostic (2.53e-1)" "potential prognostic unfavorable (3.77e-8)" "unprognostic (1.23e-3)" "unprognostic (9.56e-2)" "unprognostic (5.73e-3)" "potential prognostic favorable (1.84e-4)" "unprognostic (1.12e-1)" "unprognostic (4.89e-2)" "unprognostic (1.97e-1)" "unprognostic (2.00e-2)" "unprognostic (2.25e-1)" "unprognostic (1.55e-1)" "unprognostic (4.95e-2)" SAAL1 FLJ41463 ENSG00000166788 "Serum amyloid A like 1" Q96ER3 11 18069935-18106087 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 47.6;Late primary spermatocytes: 60.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039003, HPA039004" Approved Supported Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" 35 Nucleoplasm "HPA039003: , HPA039004: " "unprognostic (7.84e-2)" "unprognostic (2.86e-1)" "unprognostic (1.69e-1)" "unprognostic (2.81e-3)" "unprognostic (1.88e-1)" "unprognostic (1.00e-1)" "unprognostic (3.12e-1)" "unprognostic (3.46e-2)" "unprognostic (1.34e-1)" "potential prognostic unfavorable (8.77e-4)" "unprognostic (6.30e-3)" "unprognostic (3.21e-2)" "unprognostic (1.84e-1)" "unprognostic (1.09e-3)" "unprognostic (1.87e-2)" "potential prognostic unfavorable (5.08e-5)" "unprognostic (3.33e-3)" "unprognostic (1.26e-1)" "unprognostic (2.69e-1)" "unprognostic (1.00e-1)" "unprognostic (1.11e-1)" "unprognostic (2.95e-2)" "unprognostic (6.17e-3)" "unprognostic (3.39e-2)" "unprognostic (4.26e-3)" "unprognostic (3.09e-1)" "unprognostic (7.11e-3)" "unprognostic (9.92e-2)" "unprognostic (1.98e-1)" "unprognostic (1.06e-1)" "unprognostic (9.79e-2)" SAC3D1 "HSU79266, SHD1" ENSG00000168061 "SAC3 domain containing 1" 11 65040901-65044828 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "testis: 43.8" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 101.8;Early spermatids: 82.5;Esophageal basal cells: 67.2;Late primary spermatocytes: 233.6;Late spermatids: 180.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042677 Uncertain Approved Cytosol NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 67: Testis - Mixed function" "Cluster 18: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 1 Cytosol "HPA042677: " "unprognostic (9.40e-2)" "unprognostic (3.87e-2)" "unprognostic (4.74e-2)" "unprognostic (1.65e-2)" "unprognostic (1.04e-1)" "unprognostic (4.06e-1)" "unprognostic (1.30e-1)" "unprognostic (8.42e-2)" "unprognostic (1.51e-2)" "unprognostic (4.36e-3)" "potential prognostic unfavorable (6.04e-8)" "unprognostic (1.63e-2)" "unprognostic (1.01e-3)" "validated prognostic unfavorable (1.40e-6)" "validated prognostic unfavorable (3.68e-6)" "unprognostic (1.85e-3)" "unprognostic (5.08e-2)" "unprognostic (1.35e-2)" "unprognostic (9.66e-2)" "unprognostic (1.88e-1)" "unprognostic (1.07e-1)" "unprognostic (3.43e-2)" "unprognostic (4.01e-2)" "unprognostic (1.54e-1)" "unprognostic (1.36e-1)" "unprognostic (4.89e-2)" "unprognostic (4.08e-1)" "unprognostic (1.49e-3)" "unprognostic (2.15e-1)" "unprognostic (2.89e-1)" "unprognostic (2.87e-1)" SACM1L "KIAA0851, SAC1" ENSG00000211456 "SAC1 like phosphatidylinositide phosphatase" Q9NTJ5 3 45689056-45745412 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039573, HPA069869" Approved Approved "Nucleoplasm,Golgi apparatus" NA NA 54000 "Cluster 1: T-cells - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 93 "Nucleoplasm, Golgi apparatus" "HPA039573: , HPA069869: " "unprognostic (2.18e-1)" "unprognostic (2.62e-1)" "unprognostic (1.70e-2)" "unprognostic (1.62e-1)" "unprognostic (9.23e-2)" "unprognostic (1.07e-1)" "unprognostic (1.73e-1)" "unprognostic (2.96e-1)" "unprognostic (1.89e-2)" "unprognostic (1.39e-2)" "potential prognostic favorable (1.45e-8)" "unprognostic (4.91e-3)" "unprognostic (2.08e-2)" "unprognostic (1.84e-1)" "unprognostic (4.85e-1)" "unprognostic (2.95e-2)" "unprognostic (1.19e-1)" "unprognostic (1.49e-1)" "unprognostic (3.87e-1)" "unprognostic (2.25e-1)" "unprognostic (1.47e-2)" "unprognostic (2.35e-1)" "unprognostic (5.24e-2)" "unprognostic (1.78e-2)" "unprognostic (1.65e-1)" "unprognostic (2.74e-2)" "unprognostic (1.85e-2)" "unprognostic (5.68e-2)" "unprognostic (2.32e-1)" "unprognostic (1.31e-1)" "unprognostic (2.63e-1)" SACS "ARSACS, DKFZp686B15167, DNAJC29, KIAA0730, PPP1R138, SPAX6" ENSG00000151835 "Sacsin molecular chaperone" Q9NZJ4 13 23288689-23433763 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Chaperone "Cancer-related genes, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 139.3;Cardiomyocytes: 472.3;Myonuclei: 516.4;Myosatellite cells: 148.2;Thymic myoid cells: 270.6;Thyrotrophs: 134.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB017714 Uncertain NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 72: Neuronal - Signal transduction" "Cluster 55: Myocytes - Oxidative muscle function" 3 "CAB017714: " "unprognostic (5.48e-2)" "unprognostic (2.91e-1)" "unprognostic (1.31e-1)" "unprognostic (4.65e-2)" "unprognostic (2.17e-2)" "unprognostic (8.77e-2)" "unprognostic (3.21e-3)" "unprognostic (2.18e-3)" "unprognostic (9.90e-2)" "unprognostic (8.38e-3)" "unprognostic (2.88e-2)" "unprognostic (5.02e-2)" "unprognostic (5.13e-3)" "validated prognostic unfavorable (3.96e-4)" "validated prognostic unfavorable (7.93e-4)" "unprognostic (8.83e-2)" "unprognostic (2.14e-1)" "unprognostic (1.31e-2)" "unprognostic (7.94e-2)" "unprognostic (3.07e-1)" "unprognostic (1.44e-2)" "unprognostic (2.25e-1)" "unprognostic (1.34e-2)" "unprognostic (2.94e-3)" "unprognostic (4.17e-1)" "unprognostic (4.75e-2)" "unprognostic (5.19e-2)" "unprognostic (1.06e-1)" SAE1 "AOS1, FLJ3091, Sua1" ENSG00000142230 "SUMO1 activating enzyme subunit 1" Q9UBE0 19 47113274-47210636 "Essential proteins, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 246.6;Enterocytes: 295.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Skin - Mitotic cells (Skin), Testis - Early spermatids, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041906, HPA043552" Supported Enhanced Nucleoplasm,Cytosol NA NA 17000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 74: Non-specific - Signal transduction" "Cluster 1: Neurons - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 65: Non-specific - Cell growth & division" 33 "Nucleoplasm, Cytosol" "HPA041906: , HPA043552: " "unprognostic (1.63e-2)" "unprognostic (4.06e-2)" "unprognostic (1.63e-2)" "unprognostic (3.18e-2)" "unprognostic (8.73e-2)" "unprognostic (1.99e-1)" "unprognostic (1.45e-1)" "unprognostic (2.90e-1)" "unprognostic (2.87e-1)" "unprognostic (3.31e-1)" "unprognostic (2.22e-1)" "unprognostic (3.34e-2)" "unprognostic (9.35e-3)" "validated prognostic unfavorable (1.62e-4)" "validated prognostic unfavorable (7.57e-5)" "unprognostic (1.11e-3)" "unprognostic (5.61e-3)" "unprognostic (6.51e-2)" "unprognostic (2.47e-1)" "unprognostic (2.43e-1)" "unprognostic (2.42e-1)" "unprognostic (1.44e-2)" "unprognostic (1.21e-1)" "unprognostic (1.35e-2)" "unprognostic (2.48e-1)" "unprognostic (2.94e-1)" "unprognostic (1.73e-2)" "unprognostic (2.46e-2)" "unprognostic (1.64e-1)" "unprognostic (8.20e-2)" "unprognostic (2.13e-1)" SAFB "HET, SAFB1" ENSG00000160633 "Scaffold attachment factor B" Q15424 19 5623035-5668478 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001969, HPA016832, HPA020076" Supported Enhanced Nucleoplasm,Midbody Yes NA 390000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 24: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 23: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 57 Nucleoplasm Midbody "CAB001969: , HPA016832: , HPA020076: " "unprognostic (1.84e-1)" "unprognostic (2.84e-1)" "unprognostic (1.48e-3)" "unprognostic (5.52e-2)" "unprognostic (1.50e-1)" "unprognostic (1.29e-1)" "unprognostic (6.16e-2)" "unprognostic (1.07e-2)" "unprognostic (1.34e-2)" "unprognostic (2.03e-1)" "unprognostic (1.19e-3)" "unprognostic (1.68e-3)" "unprognostic (7.48e-2)" "potential prognostic unfavorable (3.36e-4)" "unprognostic (3.98e-2)" "unprognostic (1.24e-1)" "unprognostic (9.01e-3)" "unprognostic (1.43e-1)" "unprognostic (1.06e-3)" "unprognostic (1.58e-1)" "unprognostic (2.88e-2)" "unprognostic (1.34e-3)" "unprognostic (6.96e-3)" "unprognostic (7.03e-3)" "unprognostic (3.37e-2)" "unprognostic (4.74e-2)" "unprognostic (3.74e-2)" "unprognostic (6.85e-2)" "unprognostic (7.60e-2)" "unprognostic (3.72e-2)" "unprognostic (4.37e-2)" SAFB2 KIAA0138 ENSG00000130254 "Scaffold attachment factor B2" Q14151 19 5586999-5624046 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050894 Approved Supported "Nucleoplasm,Nuclear bodies,Vesicles" NA NA 260000 "Cluster 21: Neutrophils - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 23: Non-specific - Transcription" "Cluster 20: Non-specific - Transcription regulation" 49 Nucleoplasm "Nuclear bodies, Vesicles" "HPA050894: " "unprognostic (4.97e-2)" "unprognostic (6.83e-2)" "unprognostic (2.04e-2)" "unprognostic (1.27e-1)" "unprognostic (6.98e-3)" "unprognostic (2.83e-1)" "unprognostic (1.59e-1)" "unprognostic (2.64e-2)" "unprognostic (2.18e-3)" "unprognostic (6.18e-2)" "validated prognostic favorable (9.48e-5)" "validated prognostic favorable (7.59e-5)" "unprognostic (1.07e-2)" "potential prognostic unfavorable (3.49e-4)" "unprognostic (2.95e-1)" "unprognostic (1.00e-1)" "unprognostic (4.30e-1)" "unprognostic (4.61e-1)" "unprognostic (5.68e-2)" "unprognostic (2.16e-1)" "unprognostic (6.13e-2)" "potential prognostic favorable (1.90e-4)" "unprognostic (6.32e-3)" "potential prognostic unfavorable (7.31e-4)" "unprognostic (5.15e-2)" "unprognostic (4.56e-2)" "unprognostic (9.60e-2)" "unprognostic (2.00e-2)" "unprognostic (9.90e-2)" "unprognostic (2.73e-1)" "unprognostic (1.96e-2)" SAG "ARRESTIN, RP47" ENSG00000130561 "S-antigen visual arrestin" P10523 2 233307816-233347055 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Congenital stationary night blindness, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 353 "retina: 1359.9" "Cell type enriched" "Detected in some" 11 "Rod photoreceptor cells: 1864.4" "Cell type enhanced" "Detected in single" "medium spiny neuron: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "basal ganglia: 5.2" HPA004946 Enhanced NA NA "Cluster 42: Retina - Visual perception" "Cluster 79: Photoreceptor cells - Phototransduction" 2 "HPA004946: " "unprognostic (1.45e-2)" SAGE1 "CT14, SAGE" ENSG00000181433 "Sarcoma antigen 1" Q9NXZ1 X 135889205-135913062 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 14 "testis: 4.5" "Group enriched" "Detected in some" 11 "Differentiating spermatogonia: 16.5;Early primary spermatocytes: 4.2;Undifferentiated spermatogonia: 8.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 6.5" "Testis - Spermatogonia" "HPA003033, HPA003208" Enhanced Enhanced "Nucleoplasm,Nuclear bodies" NA NA "Cluster 67: Testis - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 106: Spermatogonia - Spermatogonial differentiation" Nucleoplasm "Nuclear bodies" "HPA003033: , HPA003208: " "unprognostic (5.46e-3)" "unprognostic (1.72e-1)" "unprognostic (4.08e-1)" SAGSIN1 ENSG00000286075 "Salivary gland specific protein SAGSIN1" 7 6329411-6348967 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "skeletal muscle: 41.2;testis: 25.7" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 2.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 61: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 67: Non-specific - Unknown function" "unprognostic (2.06e-1)" "unprognostic (3.76e-1)" "unprognostic (4.65e-1)" SALL1 "Hsal1, TBS, ZNF794" ENSG00000103449 "Spalt like transcription factor 1" Q9NSC2 16 51135982-51152334 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" Deafness "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.2;kidney: 31.7;liver: 34.3" "Cell type enhanced" "Detected in some" "Astrocytes: 20.6;Cone photoreceptor cells: 37.3;Distal convoluted tubule cells: 24.1;Endometrial glandular cells: 19.3;Endometrial luminal cells: 21.4;Endometrial stromal cells: 25.6;Ependymal cells: 19.5;Epididymal efferent duct absorptive cells: 31.2;Hepatocytes: 44.7;Loop of henle epithelial cells: 54.4;Microglia: 84.9;Oligodendrocytes: 40.5;Pituitary stem cells: 73.9;Proximal tubule cells: 41.5" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 94.8;oligodendrocyte: 61.7" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 46.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Macrophages, Testis - Spermatogonia" "Region enhanced" "Detected in all" "olfactory bulb: 52.6" "Low region specificity" "Detected in all" "HPA049829, HPA074673" Enhanced Approved "Nucleoplasm,Nucleoli,Nuclear speckles,Cytosol" NA NA "Cluster 76: Non-specific - Metabolism" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 18 Nucleoplasm "Nucleoli, Nuclear speckles, Cytosol" "HPA049829: , HPA074673: " "unprognostic (2.12e-1)" "unprognostic (1.40e-1)" "unprognostic (2.61e-1)" "unprognostic (1.01e-1)" "unprognostic (1.99e-1)" "unprognostic (9.13e-2)" "validated prognostic favorable (3.05e-10)" "validated prognostic favorable (8.08e-4)" "unprognostic (1.88e-2)" "unprognostic (2.94e-2)" "unprognostic (1.99e-3)" "unprognostic (1.98e-1)" "unprognostic (5.01e-2)" "unprognostic (8.29e-2)" "unprognostic (2.17e-3)" "unprognostic (2.98e-1)" "unprognostic (2.89e-2)" "unprognostic (5.54e-2)" SALL2 "Hsal2, KIAA0360, ZNF795" ENSG00000165821 "Spalt like transcription factor 2" Q9Y467 14 21521080-21537216 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 64.1" "Cell type enhanced" "Detected in many" "Astrocytes: 30.1;Bergmann glia: 28.2;Cone photoreceptor cells: 18.6;Corticotrophs: 23.3;Ependymal cells: 38.3;Megakaryocytes: 24.7;Oligodendrocyte progenitor cells: 20.5;Pituicytes/FSCs: 26.1;Pituitary stem cells: 50.1" "Cell type enhanced" "Detected in all" "ependymal cell: 53.5" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 39.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD8 T-cell: 1.1" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "testis cancer: 33.4" "Adipose subcutaneous - Smooth muscle cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004162 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 65: Brain - Transcription" "Cluster 19: Astrocytes - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 10 Vesicles Nucleoplasm "HPA004162: " "unprognostic (3.11e-2)" "unprognostic (3.33e-2)" "unprognostic (8.19e-2)" "unprognostic (1.72e-1)" "unprognostic (1.13e-1)" "unprognostic (4.02e-2)" "unprognostic (9.78e-2)" "unprognostic (1.27e-1)" "unprognostic (4.72e-3)" "unprognostic (2.39e-3)" "unprognostic (6.69e-2)" "unprognostic (1.23e-1)" "unprognostic (5.03e-3)" "unprognostic (4.11e-3)" "unprognostic (1.59e-1)" "unprognostic (7.11e-2)" "unprognostic (1.98e-3)" "unprognostic (2.62e-1)" "unprognostic (2.63e-1)" "potential prognostic favorable (7.53e-4)" "unprognostic (1.36e-2)" "unprognostic (9.07e-2)" "unprognostic (1.34e-1)" "unprognostic (6.47e-2)" "unprognostic (5.05e-3)" "unprognostic (2.46e-1)" "unprognostic (1.55e-1)" "unprognostic (7.59e-2)" SALL3 ZNF796 ENSG00000256463 "Spalt like transcription factor 3" Q9BXA9 18 78979818-79002677 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 8.5;cervix: 2.2;kidney: 2.8;prostate: 5.2;vagina: 6.8" "Cell type enhanced" "Detected in some" "Astrocytes: 62.2;Distal convoluted tubule cells: 128.4;Ependymal cells: 33.5;Oligodendrocyte progenitor cells: 72.8;Renal connecting tubule cells: 29.7" "Cell type enhanced" "Detected in some" "astrocyte: 63.0;ependymal cell: 40.4;mammillary body: 37.5;oligodendrocyte precursor cell: 77.5" "Cancer enriched" "Detected in some" 8 "Glioblastoma Multiforme (TCGA): 8.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Prostate - Prostate basal glandular cells, Testis - Spermatogonia" "Region enriched" "Detected in many" 4 "olfactory bulb: 12.5" "Low region specificity" "Detected in many" HPA016656 Uncertain NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 43: Hindbrain - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" "HPA016656: " "unprognostic (1.26e-1)" "unprognostic (2.02e-2)" "unprognostic (1.13e-1)" "unprognostic (3.41e-1)" "unprognostic (3.41e-1)" SALL4 "dJ1112F19.1, ZNF797" ENSG00000101115 "Spalt like transcription factor 4" Q9UJQ4 20 51782331-51802521 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Deafness, Disease variant, Oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 3.8;thyroid gland: 5.6" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 21.3;Conjunctival goblet cells: 7.8;Gastric progenitor cells: 10.3;Oocytes: 9.2;Pancreatic duct cells: 11.1;Pancreatic islet cells: 7.7;Respiratory secretory cells: 7.2;Retinal horizontal cells: 30.1;Sertoli cells: 22.7;Undifferentiated spermatogonia: 11.1;Urothelial cells: 6.6" "Cell type enhanced" "Detected in some" "fibroblast: 3.2" "Cancer enriched" "Detected in many" 14 "Testicular Germ Cell Tumor (TCGA): 52.8" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 9 "NK-cell: 2.5" "Lineage enriched" "Detected in single" 9 "NK-cells: 2.5" "Cancer enhanced" "Detected in many" "testis cancer: 36.6" "Testis - Sertoli cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015291, HPA015791" Enhanced Supported Nucleoplasm,Vesicles Yes No "Cluster 21: Testis - Mixed function" "Cluster 55: Non-specific - Transcription" "Cluster 34: Testis cancer - Unknown function" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 9 Nucleoplasm Vesicles "HPA015291: , HPA015791: " "unprognostic (2.29e-1)" "unprognostic (7.69e-2)" "unprognostic (2.71e-1)" "unprognostic (1.01e-1)" "unprognostic (1.87e-1)" "unprognostic (1.36e-1)" "unprognostic (3.52e-3)" "unprognostic (7.59e-2)" "unprognostic (2.05e-2)" "unprognostic (8.43e-2)" "unprognostic (7.08e-2)" "unprognostic (2.21e-2)" "unprognostic (8.18e-2)" "unprognostic (2.26e-1)" "unprognostic (1.37e-1)" "unprognostic (3.96e-1)" "unprognostic (2.63e-2)" "unprognostic (4.78e-3)" "unprognostic (3.95e-2)" "unprognostic (6.10e-2)" "unprognostic (2.99e-1)" "unprognostic (5.41e-2)" "unprognostic (2.87e-1)" "unprognostic (2.39e-3)" "unprognostic (7.89e-3)" SAMD1 ENSG00000141858 "Sterile alpha motif domain containing 1" 19 14087851-14091036 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 12.5;Bergmann glia: 12.1;Ependymal cells: 11.9;Loop of henle epithelial cells: 7.8;Microglia: 12.0;Oligodendrocyte progenitor cells: 11.1;Oligodendrocytes: 9.7;Other brain neurons: 7.8;Papillary tip epithelial cells: 10.9;Renal collecting duct intercalated cells: 6.0;Renal collecting duct principal cells: 10.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA049059, HPA075278" Uncertain Approved "Nucleoplasm,Mitotic chromosome" "Intracellular and membrane" Yes NA "Cluster 33: Non-specific - ATP binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" 2 Nucleoplasm "Mitotic chromosome" "HPA049059: , HPA075278: " "unprognostic (5.03e-2)" "unprognostic (1.14e-1)" "unprognostic (1.08e-1)" "unprognostic (2.41e-1)" "unprognostic (1.71e-1)" "unprognostic (5.17e-2)" "unprognostic (2.26e-2)" "unprognostic (1.09e-2)" "unprognostic (1.06e-3)" "unprognostic (2.84e-1)" "unprognostic (4.29e-3)" "potential prognostic unfavorable (6.49e-4)" "unprognostic (1.45e-2)" "potential prognostic unfavorable (1.26e-6)" "unprognostic (1.45e-2)" "unprognostic (1.00e-2)" "unprognostic (2.55e-3)" "unprognostic (1.63e-1)" "unprognostic (3.37e-2)" "unprognostic (1.62e-2)" "unprognostic (8.85e-2)" "unprognostic (1.24e-2)" "unprognostic (1.81e-1)" "unprognostic (4.05e-2)" "unprognostic (2.22e-1)" "unprognostic (8.92e-2)" "unprognostic (1.32e-2)" "unprognostic (2.43e-3)" "unprognostic (3.42e-1)" "unprognostic (7.34e-2)" "unprognostic (4.47e-2)" SAMD10 C20orf136 ENSG00000130590 "Sterile alpha motif domain containing 10" Q9BYL1 20 63974116-63980008 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 29.7" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 12.1;Breast lactating cells: 12.9;Esophageal apical cells: 51.0;Esophageal suprabasal cells: 17.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 1.6;T-cells: 3.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA040973 Approved Approved Nucleoplasm NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 59: Leukemia - T-cell receptor" "Cluster 35: Neurons - Synaptic function & neurogenesis" Nucleoplasm "HPA040973: " "unprognostic (1.15e-3)" "unprognostic (6.48e-2)" "unprognostic (2.29e-1)" "unprognostic (1.41e-1)" "unprognostic (7.31e-2)" "unprognostic (6.31e-2)" "unprognostic (1.77e-1)" "unprognostic (8.70e-2)" "unprognostic (4.56e-3)" "unprognostic (9.47e-2)" "unprognostic (9.90e-3)" "unprognostic (2.86e-2)" "unprognostic (3.57e-2)" "potential prognostic unfavorable (5.33e-4)" "unprognostic (5.35e-2)" "unprognostic (4.44e-2)" "unprognostic (4.20e-2)" "unprognostic (2.56e-1)" "unprognostic (2.40e-1)" "unprognostic (7.93e-2)" "unprognostic (4.09e-1)" "unprognostic (4.32e-2)" "unprognostic (8.78e-2)" "unprognostic (2.17e-1)" "unprognostic (6.95e-2)" "unprognostic (1.51e-2)" "unprognostic (1.94e-2)" "unprognostic (7.02e-3)" "unprognostic (2.38e-1)" "unprognostic (2.53e-1)" "unprognostic (8.05e-2)" SAMD11 MGC45873 ENSG00000187634 "Sterile alpha motif domain containing 11" Q96NU1 1 923923-944575 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 34.8" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 63.8;Corticotrophs: 37.7;Endometrial stromal cells: 36.6;Pancreatic islet cells: 72.1;Podocytes: 38.2;Rod photoreceptor cells: 152.9;Smooth muscle cells: 47.4;Somatotrophs: 62.9;Thymic myoid cells: 51.7;Thyrotrophs: 42.5;Undifferentiated spermatogonia: 32.7" "Cell type enhanced" "Detected in many" "astrocyte: 26.2" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 41.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 12 "NK-cell: 1.3" "Lineage enriched" "Detected in single" 12 "NK-cells: 1.3" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Lung - Fibroblasts_2, Pituitary gland - Thyrotropes, Stomach - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA030110 Approved Nucleoplasm,Vesicles NA NA "Cluster 64: Non-specific - Transcription" "Cluster 39: Astrocytes - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 79: Photoreceptor cells - Phototransduction" 19 "Nucleoplasm, Vesicles" "HPA030110: " "unprognostic (1.55e-1)" "unprognostic (8.76e-2)" "unprognostic (9.42e-2)" "unprognostic (2.50e-1)" "unprognostic (8.10e-3)" "unprognostic (7.65e-2)" "unprognostic (2.33e-2)" "potential prognostic favorable (2.04e-5)" "unprognostic (2.77e-1)" "unprognostic (1.36e-1)" "unprognostic (2.78e-2)" "unprognostic (1.70e-3)" "unprognostic (1.66e-1)" "unprognostic (2.28e-3)" "unprognostic (4.22e-1)" "unprognostic (8.25e-2)" "potential prognostic unfavorable (6.81e-4)" "unprognostic (1.80e-1)" "unprognostic (1.66e-1)" "unprognostic (1.08e-1)" "unprognostic (1.27e-2)" "unprognostic (2.31e-1)" "unprognostic (1.41e-1)" "unprognostic (3.85e-2)" "unprognostic (4.01e-1)" "unprognostic (5.40e-2)" "unprognostic (9.28e-3)" "unprognostic (7.24e-2)" "unprognostic (2.05e-1)" SAMD12 FLJ39458 ENSG00000177570 "Sterile alpha motif domain containing 12" Q8N8I0 8 118189455-118622112 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Epilepsy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Lactotrophs: 978.2;Oligodendrocytes: 1005.0;Renal collecting duct principal cells: 795.3;Somatotrophs: 833.7;Thyrotrophs: 1054.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Pituitary gland - Lactotropes, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024634 Uncertain Approved "Golgi apparatus,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 34: Non-specific - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 2 "Golgi apparatus, Cytosol" "HPA024634: " "unprognostic (4.26e-3)" "unprognostic (9.00e-2)" "unprognostic (6.36e-2)" "unprognostic (2.59e-1)" "unprognostic (1.34e-1)" "unprognostic (1.77e-2)" "unprognostic (1.28e-1)" "unprognostic (2.27e-1)" "unprognostic (3.61e-3)" "unprognostic (1.29e-3)" "potential prognostic favorable (5.12e-4)" "unprognostic (6.09e-2)" "unprognostic (1.15e-2)" "unprognostic (7.07e-2)" "unprognostic (2.56e-1)" "unprognostic (2.38e-1)" "unprognostic (3.00e-2)" "unprognostic (1.73e-2)" "unprognostic (2.76e-2)" "unprognostic (3.47e-3)" "unprognostic (4.27e-2)" "unprognostic (3.43e-1)" "unprognostic (1.57e-1)" "unprognostic (5.35e-2)" "unprognostic (4.71e-2)" "unprognostic (1.58e-1)" "unprognostic (1.36e-1)" SAMD13 ENSG00000203943 "Sterile alpha motif domain containing 13" Q5VXD3 1 84298366-84389957 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 20.6;salivary gland: 16.5" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 53.2;Colonocytes: 58.9;Enteric stem cells: 45.3;Enteric transient amplifying cells: 44.1;Late primary spermatocytes: 54.5;Parietal cells: 51.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 15 "basophil: 12.5" "Lineage enriched" "Detected in single" 15 "granulocytes: 12.5" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA058929 Enhanced Approved Mitochondria NA NA "Cluster 41: Basophils - Unknown function" "Cluster 21: Testis - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 1 Mitochondria "HPA058929: " "unprognostic (1.03e-2)" "unprognostic (8.35e-2)" "unprognostic (1.23e-1)" "unprognostic (1.06e-1)" "unprognostic (1.01e-2)" "unprognostic (9.94e-3)" "potential prognostic favorable (1.15e-5)" "unprognostic (2.40e-2)" "unprognostic (6.66e-2)" "potential prognostic favorable (5.09e-5)" "unprognostic (3.22e-2)" "unprognostic (1.11e-3)" "potential prognostic unfavorable (9.24e-4)" "unprognostic (1.31e-1)" "unprognostic (1.40e-2)" "unprognostic (1.26e-2)" "unprognostic (1.70e-2)" "unprognostic (2.57e-1)" "unprognostic (4.97e-2)" "potential prognostic favorable (3.51e-4)" "unprognostic (5.17e-1)" "unprognostic (2.61e-2)" "unprognostic (2.34e-2)" "unprognostic (1.15e-1)" "unprognostic (1.44e-1)" "unprognostic (1.98e-1)" "unprognostic (1.00e-1)" "unprognostic (1.31e-1)" SAMD14 FLJ36890 ENSG00000167100 "Sterile alpha motif domain containing 14" Q8IZD0 17 50110040-50130160 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "brain: 67.0" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 25.1;Cardiomyocytes: 37.2;Epididymal principal cells: 40.6;Megakaryocytes: 234.9;Platelets: 73.1;Retinal amacrine cells: 32.9;Retinal bipolar cells: 60.9" "Cell type enhanced" "Detected in many" "upper rhombic lip: 46.0" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 9.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 6.0;Neuroblastoma: 9.8" "Adipose subcutaneous - Smooth muscle cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051916 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "Nucleoplasm, Nucleoli fibrillar center" "HPA051916: " "unprognostic (1.47e-1)" "unprognostic (1.50e-1)" "unprognostic (1.45e-1)" "unprognostic (9.12e-2)" "potential prognostic favorable (1.49e-4)" "unprognostic (1.68e-1)" "unprognostic (1.07e-1)" "unprognostic (4.71e-2)" "unprognostic (1.38e-1)" "unprognostic (1.26e-1)" "unprognostic (1.77e-2)" "unprognostic (3.18e-2)" "unprognostic (1.32e-1)" "unprognostic (2.70e-3)" "unprognostic (7.36e-2)" "unprognostic (1.20e-1)" SAMD15 "C14orf174, FAM15A, FLJ35963" ENSG00000100583 "Sterile alpha motif domain containing 15" Q9P1V8 14 77376689-77392163 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "retina: 13.8;testis: 15.0" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 55.9;Early spermatids: 72.6;Endometrial ciliated cells: 47.2;Ependymal cells: 32.5;Epididymal efferent duct ciliated cells: 31.5;Fallopian tube ciliated cells: 55.9;Late primary spermatocytes: 130.1;Late spermatids: 190.3;Respiratory ciliated cells: 85.2;Rod photoreceptor cells: 50.0" "Cell type enhanced" "Detected in many" "ependymal cell: 29.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "HPA030673, HPA030677" Enhanced Approved "Nucleoplasm,Nuclear membrane,Nucleoli,Cytosol" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" "Nucleoplasm, Nuclear membrane" "Nucleoli, Cytosol" "HPA030673: , HPA030677: " "unprognostic (4.40e-2)" "unprognostic (3.10e-1)" "unprognostic (2.81e-2)" "unprognostic (1.07e-2)" "unprognostic (6.17e-3)" "unprognostic (7.24e-3)" "unprognostic (2.87e-2)" "potential prognostic favorable (5.14e-4)" "unprognostic (2.27e-2)" "unprognostic (2.56e-1)" "unprognostic (2.04e-1)" "unprognostic (2.30e-1)" "unprognostic (5.82e-3)" "unprognostic (3.01e-1)" "unprognostic (2.65e-1)" "unprognostic (6.36e-2)" "potential prognostic unfavorable (2.95e-4)" "unprognostic (2.35e-1)" "unprognostic (8.85e-3)" "unprognostic (3.40e-1)" "unprognostic (5.85e-2)" "unprognostic (1.42e-1)" SAMD3 "bA73O6.2, FLJ34032" ENSG00000164483 "Sterile alpha motif domain containing 3" Q8N6K7 6 130144315-130365425 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 9.7" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 167.6;Brain excitatory neurons: 139.7;Gonadotrophs: 190.4;Lactotrophs: 159.0;Neuroendocrine cells: 221.4;NK-cells: 533.6;Other brain neurons: 106.8;Pancreatic islet cells: 227.9;Retinal ganglion cells: 220.2;Somatotrophs: 167.5;T-cells: 233.6;Thyrotrophs: 153.1" "Cell type enhanced" "Detected in many" "hippocampal CA1-3: 421.1;hippocampal dentate gyrus: 483.7;leukocyte: 671.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 47 "NK-cells: 128.7;T-cells: 114.1" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Minor Salivary Gland - T-cells, Prostate - T-cells, Testis - Early spermatids, Thyroid gland - T-cells" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebellum: 2.8" "HPA028992, HPA028993" Uncertain NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 29: Forebrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 6 "HPA028992: , HPA028993: " "unprognostic (1.13e-2)" "potential prognostic favorable (4.34e-4)" "potential prognostic favorable (6.80e-5)" "unprognostic (4.91e-2)" "unprognostic (3.36e-3)" "unprognostic (2.44e-1)" "unprognostic (1.00e-1)" "unprognostic (5.37e-2)" "unprognostic (3.34e-3)" "unprognostic (6.13e-3)" "unprognostic (5.70e-2)" "unprognostic (5.82e-2)" "unprognostic (3.23e-2)" "unprognostic (4.34e-2)" "unprognostic (8.89e-2)" "unprognostic (7.77e-2)" "unprognostic (7.08e-2)" "unprognostic (1.97e-1)" SAMD4A "DKFZP434H0350, hSmaug1, KIAA1053, SAMD4, Smaug, SMG, SMGA" ENSG00000020577 "Sterile alpha motif domain containing 4A" Q9UPU9 14 54566117-54793315 "Predicted intracellular proteins" "Translation regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 78.3;skeletal muscle: 88.3;testis: 99.6" "Cell type enhanced" "Detected in many" "Bergmann glia: 1013.8;Cardiomyocytes: 972.0;Early spermatids: 1632.6;Epididymal clear cells: 920.6;Late spermatids: 3388.9;Myonuclei: 1443.5;Pituicytes/FSCs: 1142.3;Smooth muscle cells: 1341.3" "Cell type enhanced" "Detected in all" "Bergmann glia: 996.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.2;non-classical monocyte: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Spleen - Endothelial cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043061, HPA065309" Approved Approved "Cell Junctions,Cytosol" NA NA "Cluster 67: Testis - Mixed function" "Cluster 43: Hindbrain - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 103: Non-specific - Basic cellular processes" 13 "Cell Junctions" Cytosol "HPA043061: , HPA065309: " "unprognostic (3.37e-2)" "unprognostic (5.10e-2)" "unprognostic (2.29e-2)" "unprognostic (7.21e-3)" "unprognostic (7.06e-3)" "unprognostic (7.43e-3)" "unprognostic (2.04e-1)" "unprognostic (2.53e-2)" "unprognostic (4.85e-2)" "unprognostic (2.70e-1)" "potential prognostic favorable (4.78e-4)" "unprognostic (1.50e-2)" "unprognostic (6.70e-2)" "unprognostic (1.35e-1)" "unprognostic (1.99e-2)" "unprognostic (2.98e-2)" "unprognostic (2.05e-3)" "unprognostic (4.48e-2)" "unprognostic (4.04e-1)" "unprognostic (2.67e-2)" "potential prognostic unfavorable (6.33e-5)" "unprognostic (1.95e-1)" "unprognostic (5.46e-2)" "unprognostic (1.35e-1)" "unprognostic (8.46e-2)" "unprognostic (1.03e-1)" "unprognostic (2.27e-1)" "unprognostic (1.47e-2)" "unprognostic (8.05e-3)" "unprognostic (3.71e-2)" "unprognostic (9.91e-2)" SAMD4B "FLJ10211, hSmaug2, MGC99832, SMGB" ENSG00000179134 "Sterile alpha motif domain containing 4B" Q5PRF9 19 39342421-39385710 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 306.5;Neutrophils: 364.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016800, HPA059385" Approved Enhanced Cytosol No No "Cluster 35: Neutrophils - Protein binding" "Cluster 74: Non-specific - Signal transduction" "Cluster 19: Astrocytes - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 36 Cytosol "HPA016800: , HPA059385: " "unprognostic (7.22e-2)" "unprognostic (7.24e-2)" "unprognostic (1.92e-1)" "unprognostic (1.71e-3)" "unprognostic (8.92e-2)" "unprognostic (1.10e-2)" "unprognostic (2.35e-1)" "unprognostic (3.14e-1)" "unprognostic (2.27e-1)" "unprognostic (1.15e-1)" "unprognostic (1.18e-3)" "unprognostic (4.79e-2)" "unprognostic (1.71e-1)" "unprognostic (2.76e-2)" "unprognostic (4.84e-2)" "unprognostic (2.88e-2)" "unprognostic (1.23e-1)" "unprognostic (2.69e-2)" "unprognostic (1.37e-1)" "unprognostic (5.26e-2)" "unprognostic (2.85e-1)" "unprognostic (3.39e-2)" "unprognostic (7.87e-3)" "unprognostic (7.72e-2)" "unprognostic (9.12e-2)" "unprognostic (2.92e-3)" "unprognostic (2.38e-2)" "unprognostic (1.85e-1)" "unprognostic (4.66e-2)" "unprognostic (3.60e-2)" "unprognostic (1.42e-1)" SAMD5 dJ875H10.1 ENSG00000203727 "Sterile alpha motif domain containing 5" Q5TGI4 6 147508690-147737547 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 265.9;Distal convoluted tubule cells: 556.6;Lactotrophs: 462.1;Pancreatic islet cells: 311.1;Pituicytes/FSCs: 484.5;Proximal tubule cells: 432.3;Renal collecting duct intercalated cells: 373.3;Renal connecting tubule cells: 257.4;Retinal bipolar cells: 911.4;Sertoli cells: 643.8;Thyrotrophs: 329.4" "Cell type enhanced" "Detected in all" "midbrain-derived inhibitory: 609.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal medulla cells, Kidney - Proximal tubular cells, Minor Salivary Gland - Minor salivary gland basal cells, Skeletal muscle - Fibroblasts, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Spleen - Fibroblasts_1, Stomach - Mitotic cells (Stomach), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067811 Uncertain Supported Vesicles No No "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 49: Hindbrain - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" Vesicles "HPA067811: " "unprognostic (1.78e-2)" "unprognostic (6.11e-2)" "unprognostic (9.19e-2)" "unprognostic (6.98e-2)" "unprognostic (1.39e-1)" "unprognostic (2.64e-2)" "unprognostic (1.66e-1)" "unprognostic (7.10e-2)" "unprognostic (1.19e-1)" "validated prognostic favorable (1.59e-7)" "validated prognostic favorable (1.70e-6)" "potential prognostic unfavorable (1.37e-4)" "potential prognostic unfavorable (8.61e-5)" "potential prognostic favorable (5.83e-4)" "unprognostic (2.12e-1)" "unprognostic (6.88e-3)" "unprognostic (1.00e-1)" "unprognostic (9.79e-2)" "unprognostic (6.12e-3)" "unprognostic (2.76e-1)" "unprognostic (8.13e-2)" "unprognostic (7.06e-2)" "unprognostic (1.95e-3)" "unprognostic (1.13e-1)" "unprognostic (8.45e-2)" "unprognostic (2.37e-2)" "unprognostic (1.82e-2)" "unprognostic (1.73e-1)" SAMD7 DKFZp686E1583 ENSG00000187033 "Sterile alpha motif domain containing 7" Q7Z3H4 3 169911572-169939175 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 641 "retina: 124.2" "Group enriched" "Detected in some" 14 "Cone photoreceptor cells: 78.7;Rod photoreceptor cells: 217.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 42: Retina - Visual perception" "Cluster 55: Lymphoma - Immune response" "Cluster 79: Photoreceptor cells - Phototransduction" 6 SAMD8 "FLJ25082, SMSr" ENSG00000156671 "Sterile alpha motif domain containing 8" Q96LT4 10 75099586-75182123 "Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 244.7;Neutrophils: 400.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 19.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044402 Approved "Endoplasmic reticulum,Cytosol" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 1 "Endoplasmic reticulum, Cytosol" "HPA044402: " "unprognostic (2.21e-2)" "unprognostic (8.97e-2)" "unprognostic (5.70e-1)" "unprognostic (5.59e-2)" "unprognostic (2.56e-1)" "unprognostic (6.64e-2)" "unprognostic (4.03e-2)" "potential prognostic favorable (6.66e-4)" "unprognostic (4.41e-2)" "unprognostic (8.33e-2)" "potential prognostic favorable (3.88e-4)" "unprognostic (4.17e-2)" "unprognostic (5.11e-2)" "unprognostic (1.36e-3)" "unprognostic (3.18e-1)" "unprognostic (1.20e-1)" "unprognostic (8.97e-3)" "unprognostic (4.00e-1)" "unprognostic (3.64e-1)" "unprognostic (9.76e-3)" "unprognostic (3.60e-2)" "unprognostic (1.19e-1)" "unprognostic (1.89e-3)" "unprognostic (2.86e-2)" "unprognostic (1.23e-1)" "unprognostic (8.74e-3)" "unprognostic (1.72e-1)" "unprognostic (9.22e-2)" "unprognostic (1.63e-1)" "unprognostic (6.66e-2)" "unprognostic (5.61e-2)" SAMD9 "C7orf5, FLJ20073, KIAA2004" ENSG00000205413 "Sterile alpha motif domain containing 9" Q5K651 7 93099513-93118023 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 36.7" "Cell type enriched" "Detected in many" 9 "Esophageal apical cells: 1776.8" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 47.6;leukocyte: 70.8;pericyte: 33.2" "Cancer enhanced" "Detected in all" "Head and Neck Squamous Cell Carcinoma (TCGA): 39.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Prostate - T-cells" "Low region specificity" "Detected in all" "HPA021318, HPA021319" Approved Supported Vesicles,Cytosol NA NA "Cluster 32: Basophils - Transcription" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 84: Apical squamous epithelium - Cornification" 3 Cytosol Vesicles "HPA021318: , HPA021319: " "unprognostic (1.26e-1)" "unprognostic (2.82e-1)" "unprognostic (8.42e-2)" "unprognostic (1.46e-1)" "unprognostic (2.27e-1)" "unprognostic (1.09e-1)" "unprognostic (1.10e-1)" "unprognostic (9.91e-2)" "unprognostic (7.90e-2)" "potential prognostic unfavorable (2.02e-5)" "unprognostic (5.50e-2)" "unprognostic (3.35e-2)" "unprognostic (3.38e-3)" "unprognostic (8.94e-2)" "unprognostic (1.75e-1)" "unprognostic (2.28e-3)" "unprognostic (7.55e-2)" "unprognostic (1.36e-2)" "unprognostic (2.15e-2)" "unprognostic (3.02e-1)" "unprognostic (5.91e-2)" "potential prognostic unfavorable (2.34e-4)" "unprognostic (1.80e-1)" "unprognostic (1.57e-1)" "unprognostic (1.51e-1)" "unprognostic (5.48e-2)" "unprognostic (7.16e-2)" "unprognostic (1.88e-1)" "unprognostic (4.70e-2)" "unprognostic (1.60e-2)" "unprognostic (6.38e-3)" SAMD9L "C7orf6, FLJ39885, KIAA2005" ENSG00000177409 "Sterile alpha motif domain containing 9 like" Q8IVG5 7 93130056-93148385 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 34.0" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 58.3;Microglia: 93.7;Neutrophil progenitors: 84.8;NK-cells: 55.5" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 128.4;endothelial cell: 109.9;fibroblast: 79.6;leukocyte: 94.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Myeloma: 24.9" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "HPA019461, HPA019465, HPA019488" Enhanced Approved Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 104: Brain endothelial cells - Blood brain barrier" Cytosol "HPA019461: , HPA019465: , HPA019488: " "unprognostic (9.80e-3)" "unprognostic (1.00e-2)" "unprognostic (2.15e-2)" "unprognostic (1.25e-1)" "unprognostic (1.59e-1)" "unprognostic (8.55e-2)" "unprognostic (3.98e-2)" "unprognostic (5.89e-3)" "unprognostic (4.15e-2)" "unprognostic (8.58e-2)" "unprognostic (6.16e-2)" "unprognostic (3.56e-1)" "unprognostic (2.10e-1)" "unprognostic (5.99e-2)" "unprognostic (3.71e-2)" "unprognostic (4.94e-2)" "unprognostic (6.00e-2)" "unprognostic (2.31e-2)" "unprognostic (2.83e-1)" "unprognostic (5.60e-2)" "unprognostic (4.98e-2)" "potential prognostic unfavorable (1.53e-4)" "unprognostic (2.23e-2)" "unprognostic (4.02e-1)" "unprognostic (1.14e-1)" "unprognostic (2.70e-2)" "unprognostic (5.81e-2)" "unprognostic (1.02e-1)" "unprognostic (6.70e-2)" "unprognostic (1.73e-2)" "unprognostic (3.24e-2)" SAMHD1 "AGS5, HDDC1, Mg11, MOP-5, SBBI88" ENSG00000101347 "SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1" Q9Y3Z3 20 36890229-36951893 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, DNA damage, DNA repair, DNA replication, Host-virus interaction, Immunity, Innate immunity" "Allosteric enzyme, Hydrolase" "Aicardi-Goutieres syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "cDC: 445.9;Endometrial ciliated cells: 255.1;Fallopian tube ciliated cells: 331.7;Kupffer cells: 447.9;Macrophages: 329.5;Monocyte progenitors: 510.5;monocytes: 470.0;pDCs: 347.8;Schwann cells: 907.4" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 224.0;leukocyte: 211.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Macrophages, Minor Salivary Gland - Macrophages, Skin - Macrophages, Spleen - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047072 Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 28 Nucleoplasm "Plasma membrane" "HPA047072: " "unprognostic (1.23e-1)" "unprognostic (1.03e-1)" "unprognostic (2.66e-1)" "unprognostic (9.84e-2)" "unprognostic (1.47e-1)" "unprognostic (2.56e-1)" "unprognostic (1.55e-1)" "unprognostic (2.62e-1)" "unprognostic (3.64e-2)" "unprognostic (5.77e-2)" "potential prognostic favorable (3.04e-4)" "unprognostic (2.37e-1)" "unprognostic (1.27e-2)" "unprognostic (1.53e-2)" "unprognostic (2.86e-1)" "unprognostic (2.08e-1)" "unprognostic (3.04e-3)" "unprognostic (4.31e-2)" "unprognostic (2.85e-1)" "unprognostic (2.26e-2)" "unprognostic (1.73e-1)" "unprognostic (2.95e-1)" "unprognostic (2.34e-1)" "unprognostic (1.43e-1)" "unprognostic (1.58e-2)" "unprognostic (5.22e-2)" "unprognostic (2.02e-1)" "unprognostic (8.59e-2)" "unprognostic (2.99e-1)" "unprognostic (1.94e-1)" "unprognostic (1.09e-1)" SAMM50 "CGI-51, OMP85, SAM50, TOB55, TRG-3, YNL026W" ENSG00000100347 "SAMM50 sorting and assembly machinery component" Q9Y512 22 43955442-44010531 "Essential proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 225.2" "Cell type enhanced" "Detected in many" "Parietal cells: 132.6" "Cell type enhanced" "Detected in all" "endothelial cell: 79.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034537 Enhanced Supported Mitochondria NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 97: Non-specific - Cellular respiration" 52 Mitochondria "HPA034537: " "unprognostic (3.65e-1)" "unprognostic (4.19e-2)" "unprognostic (3.55e-1)" "unprognostic (1.39e-1)" "unprognostic (2.44e-3)" "unprognostic (1.98e-2)" "potential prognostic favorable (9.91e-4)" "unprognostic (9.16e-3)" "unprognostic (1.42e-1)" "potential prognostic unfavorable (9.07e-4)" "potential prognostic favorable (1.40e-11)" "unprognostic (2.02e-2)" "unprognostic (3.85e-2)" "unprognostic (7.64e-3)" "unprognostic (2.50e-3)" "potential prognostic unfavorable (1.14e-5)" "unprognostic (5.38e-2)" "unprognostic (2.46e-2)" "potential prognostic favorable (8.94e-4)" "unprognostic (1.96e-1)" "unprognostic (1.04e-2)" "unprognostic (6.65e-2)" "unprognostic (3.75e-1)" "unprognostic (3.37e-1)" "unprognostic (5.30e-3)" "unprognostic (1.15e-1)" "unprognostic (1.72e-2)" "unprognostic (1.24e-1)" "unprognostic (2.64e-1)" "unprognostic (1.95e-1)" "unprognostic (4.40e-3)" SAMSN1 "HACS1, NASH1, SASH2, SH3D6B, SLy2" ENSG00000155307 "SAM domain, SH3 domain and nuclear localization signals 1" Q9NSI8 21 14485228-14658821 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 182.2;lymphoid tissue: 75.6" "Cell type enriched" "Detected in many" 5 "Neutrophils: 14700.2" "Group enriched" "Detected in many" 115 "central nervous system macrophage: 770.3;leukocyte: 405.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 315.4" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Leukemia: 69.1;lymphoma: 33.7" "Adipose subcutaneous - Macrophages, Adrenal gland - Macrophages, Liver - Neutrophils" "Region enriched" "Detected in many" 6 "olfactory bulb: 20.7" "Low region specificity" "Detected in all" "HPA010645, HPA017055, HPA046639" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 3 "Plasma membrane" Nucleoplasm "HPA010645: , HPA017055: , HPA046639: " "unprognostic (2.79e-2)" "unprognostic (7.69e-3)" "unprognostic (4.24e-1)" "unprognostic (3.64e-2)" "unprognostic (1.23e-1)" "unprognostic (1.51e-1)" "unprognostic (9.30e-2)" "unprognostic (7.43e-2)" "unprognostic (5.56e-2)" "unprognostic (1.61e-1)" "unprognostic (3.55e-2)" "unprognostic (3.36e-1)" "unprognostic (8.57e-2)" "unprognostic (7.25e-2)" "unprognostic (2.89e-1)" "unprognostic (1.04e-2)" "unprognostic (2.88e-1)" "unprognostic (1.94e-1)" "unprognostic (2.15e-1)" "unprognostic (1.75e-1)" "unprognostic (3.02e-1)" "unprognostic (1.62e-2)" "unprognostic (2.28e-3)" "unprognostic (1.95e-1)" "unprognostic (1.30e-1)" "unprognostic (1.20e-2)" "unprognostic (7.69e-2)" "unprognostic (7.58e-2)" "unprognostic (4.79e-2)" "unprognostic (1.72e-1)" "unprognostic (1.77e-1)" SANBR KIAA1841 ENSG00000162929 "SANT and BTB domain regulator of CSR" Q6NSI8 2 61065871-61138034 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 10.4" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 108.7;Cone photoreceptor cells: 99.4;Ependymal cells: 135.2;Other brain neurons: 113.1;Respiratory ciliated cells: 156.8;Retinal ganglion cells: 227.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Lung - Respiratory ciliated cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051240 Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 109: Neurons - Neuronal signaling" "Nucleoplasm, Nucleoli" "HPA051240: " "unprognostic (8.67e-3)" "unprognostic (3.79e-2)" "unprognostic (1.31e-1)" "unprognostic (1.05e-1)" "unprognostic (5.14e-2)" "unprognostic (1.29e-2)" "unprognostic (2.09e-1)" "unprognostic (3.45e-2)" "unprognostic (4.52e-3)" "unprognostic (6.72e-2)" "unprognostic (1.49e-1)" "unprognostic (1.26e-1)" "unprognostic (1.80e-3)" "unprognostic (5.41e-2)" "unprognostic (1.25e-1)" "unprognostic (7.55e-2)" "unprognostic (1.64e-1)" "unprognostic (5.44e-2)" "unprognostic (1.74e-1)" "unprognostic (1.21e-1)" "unprognostic (6.73e-3)" "unprognostic (7.14e-3)" "potential prognostic favorable (3.77e-4)" "unprognostic (3.39e-1)" "unprognostic (6.21e-3)" "unprognostic (2.89e-2)" "unprognostic (6.93e-2)" "unprognostic (1.47e-1)" "unprognostic (9.38e-3)" SAP130 FLJ12761 ENSG00000136715 "Sin3A associated protein 130" Q9H0E3 2 127941217-128028120 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 44.2" "Cell type enhanced" "Detected in many" "Somatotrophs: 190.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pituitary gland - Somatotropes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034664 Supported "Nuclear speckles" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 39: Testis - Nuclear processes" "Cluster 16: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 40 "Nuclear speckles" "HPA034664: " "unprognostic (1.66e-1)" "unprognostic (3.48e-1)" "unprognostic (1.88e-1)" "unprognostic (9.95e-2)" "unprognostic (2.52e-1)" "unprognostic (3.84e-1)" "unprognostic (7.68e-2)" "unprognostic (1.84e-1)" "unprognostic (2.96e-1)" "unprognostic (2.62e-3)" "potential prognostic favorable (9.00e-4)" "unprognostic (1.68e-2)" "unprognostic (7.67e-2)" "potential prognostic unfavorable (9.90e-6)" "unprognostic (1.08e-1)" "unprognostic (1.64e-1)" "unprognostic (2.09e-1)" "unprognostic (7.04e-2)" "unprognostic (2.11e-3)" "unprognostic (4.41e-1)" "unprognostic (5.53e-1)" "unprognostic (3.98e-2)" "unprognostic (1.88e-2)" "unprognostic (1.68e-1)" "unprognostic (5.14e-2)" "unprognostic (1.43e-1)" "unprognostic (2.05e-2)" "unprognostic (1.16e-1)" "unprognostic (1.77e-1)" "unprognostic (9.90e-2)" "unprognostic (9.87e-2)" SAP18 "2HOR0202, MGC27131, SAP18p" ENSG00000150459 "Sin3A associated protein 18" O00422 13 21140119-21149097 "Essential proteins, Predicted intracellular proteins, Transporters" "mRNA processing, mRNA splicing, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 1229.3;Esophageal apical cells: 1096.6;Late primary spermatocytes: 1512.9;Oocytes: 1358.5;Syncytiotrophoblasts: 1064.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011352, CAB012273" Supported Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 20: Non-specific - Transcription regulation" 108 "Nucleoplasm, Nuclear bodies" Cytosol "CAB012273: , HPA011352: " "unprognostic (3.65e-2)" "unprognostic (3.22e-1)" "unprognostic (2.51e-1)" "potential prognostic unfavorable (4.15e-4)" "unprognostic (3.80e-2)" "unprognostic (1.66e-1)" "unprognostic (1.67e-1)" "unprognostic (1.68e-1)" "potential prognostic unfavorable (9.75e-4)" "unprognostic (7.38e-3)" "potential prognostic favorable (9.17e-6)" "unprognostic (5.71e-2)" "unprognostic (2.17e-2)" "unprognostic (3.23e-2)" "unprognostic (1.89e-2)" "unprognostic (5.44e-2)" "unprognostic (7.14e-3)" "unprognostic (6.23e-2)" "unprognostic (1.65e-1)" "unprognostic (1.22e-1)" "unprognostic (7.08e-3)" "unprognostic (2.29e-3)" "unprognostic (6.74e-2)" "unprognostic (1.89e-2)" "unprognostic (5.57e-2)" "unprognostic (1.98e-1)" "unprognostic (3.39e-1)" "unprognostic (9.60e-2)" "unprognostic (5.53e-2)" "unprognostic (2.37e-2)" "unprognostic (1.80e-1)" SAP25 FLJ00248 ENSG00000205307 "Sin3A associated protein 25" Q8TEE9 7 100572228-100573900 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 55.4" "Cell type enhanced" "Detected in some" "Astrocytes: 11.2;Bergmann glia: 9.0;Choroid plexus epithelial cells: 5.6;Distal convoluted tubule cells: 8.1;Loop of henle epithelial cells: 6.4;Microglia: 34.1;Oligodendrocytes: 8.3;Podocytes: 9.5;Renal collecting duct intercalated cells: 14.9;Renal connecting tubule cells: 7.2" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 40.7;leukocyte: 24.9" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 71.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.1" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in all" "Leukemia: 23.5" "Breast - T-cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA062610 Approved "Nuclear bodies" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 5: Spleen - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 35: RS4;11 - Unknown function" "Cluster 102: Non-specific - Mixed function" 1 "Nuclear bodies" "HPA062610: " "unprognostic (2.12e-2)" "unprognostic (9.50e-2)" "unprognostic (1.19e-1)" "potential prognostic unfavorable (7.79e-5)" "unprognostic (7.54e-2)" "unprognostic (2.53e-2)" "unprognostic (7.04e-3)" "unprognostic (5.40e-2)" "potential prognostic unfavorable (4.53e-9)" "unprognostic (1.36e-2)" "unprognostic (2.75e-2)" "unprognostic (1.33e-1)" "unprognostic (1.93e-1)" "unprognostic (3.13e-2)" "unprognostic (1.53e-1)" "unprognostic (8.71e-2)" "unprognostic (3.73e-2)" "unprognostic (1.69e-1)" "unprognostic (1.17e-2)" "unprognostic (3.00e-2)" "unprognostic (2.99e-2)" "unprognostic (1.73e-1)" "unprognostic (1.50e-2)" "unprognostic (1.50e-1)" "unprognostic (2.65e-2)" "unprognostic (2.19e-1)" "unprognostic (7.55e-2)" "unprognostic (4.03e-2)" SAP30 ENSG00000164105 "Sin3A associated protein 30" O75446 4 173369969-173377532 "Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric progenitor cells: 94.8;Macrophages: 100.5;Monocyte progenitors: 126.2;monocytes: 174.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Macrophages, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022627, HPA059012" Enhanced Supported Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 74: Non-specific - Signal transduction" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 87 Nucleoplasm "CAB022627: , HPA059012: " "unprognostic (1.96e-1)" "unprognostic (6.79e-2)" "unprognostic (5.32e-2)" "unprognostic (3.72e-1)" "unprognostic (4.34e-2)" "unprognostic (2.39e-3)" "unprognostic (7.07e-3)" "unprognostic (1.60e-3)" "unprognostic (4.62e-2)" "unprognostic (1.77e-3)" "unprognostic (4.43e-2)" "unprognostic (5.27e-3)" "unprognostic (2.59e-2)" "validated prognostic unfavorable (9.63e-9)" "validated prognostic unfavorable (3.03e-4)" "unprognostic (2.14e-3)" "unprognostic (2.48e-2)" "potential prognostic favorable (8.48e-5)" "unprognostic (3.22e-1)" "unprognostic (1.15e-1)" "unprognostic (1.52e-1)" "unprognostic (3.13e-1)" "unprognostic (1.18e-1)" "unprognostic (9.85e-3)" "unprognostic (1.98e-1)" "unprognostic (1.85e-2)" "unprognostic (9.40e-2)" "unprognostic (1.20e-1)" "unprognostic (6.09e-2)" "unprognostic (1.83e-1)" "unprognostic (5.04e-2)" SAP30BP "HCNGP, HTRG, HTRP" ENSG00000161526 "SAP30 binding protein" Q9UHR5 17 75667251-75708062 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 243.5;Neutrophils: 316.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042382, HPA052943" Supported Enhanced Nucleoplasm NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 46: Brainstem - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 23 Nucleoplasm "HPA042382: , HPA052943: " "unprognostic (2.14e-1)" "unprognostic (1.13e-1)" "unprognostic (3.47e-2)" "unprognostic (2.10e-1)" "unprognostic (7.48e-2)" "potential prognostic favorable (4.72e-4)" "unprognostic (1.38e-1)" "potential prognostic favorable (6.66e-4)" "unprognostic (9.68e-2)" "unprognostic (1.50e-1)" "unprognostic (8.31e-3)" "unprognostic (5.55e-2)" "unprognostic (1.38e-1)" "potential prognostic unfavorable (4.99e-6)" "unprognostic (3.10e-3)" "unprognostic (1.41e-3)" "potential prognostic unfavorable (9.73e-5)" "unprognostic (2.24e-1)" "unprognostic (2.68e-1)" "unprognostic (6.93e-2)" "unprognostic (2.29e-2)" "unprognostic (3.41e-2)" "potential prognostic unfavorable (6.13e-4)" "unprognostic (1.64e-2)" "unprognostic (2.38e-1)" "unprognostic (2.16e-2)" "unprognostic (7.07e-3)" "unprognostic (2.58e-1)" "unprognostic (2.07e-1)" "unprognostic (2.52e-1)" "unprognostic (3.94e-1)" SAP30L "FLJ11526, NS4ATP2" ENSG00000164576 "SAP30 like" Q9HAJ7 5 154445997-154461053 "Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048665, HPA078308" Approved Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 24: Neutrophils - Innate immunity signal integration" 24 "Nucleoplasm, Nucleoli fibrillar center" "HPA048665: , HPA078308: " "unprognostic (1.27e-3)" "unprognostic (7.09e-3)" "unprognostic (7.13e-3)" "unprognostic (3.68e-2)" "unprognostic (4.27e-2)" "unprognostic (2.98e-1)" "unprognostic (5.23e-2)" "unprognostic (3.15e-1)" "unprognostic (5.88e-3)" "unprognostic (5.85e-2)" "validated prognostic favorable (4.03e-9)" "validated prognostic favorable (4.85e-5)" "unprognostic (3.06e-1)" "unprognostic (7.74e-2)" "unprognostic (2.21e-2)" "unprognostic (1.66e-1)" "unprognostic (1.77e-1)" "unprognostic (1.61e-1)" "unprognostic (2.48e-1)" "unprognostic (1.62e-2)" "unprognostic (1.97e-1)" "unprognostic (9.03e-3)" "unprognostic (1.41e-1)" "unprognostic (3.48e-1)" "unprognostic (4.38e-2)" "unprognostic (1.56e-2)" "unprognostic (2.32e-1)" "unprognostic (1.09e-1)" "unprognostic (9.62e-2)" "unprognostic (1.25e-2)" "unprognostic (1.34e-1)" SAPCD1 "C6orf26, NG23" ENSG00000228727 "Suppressor APC domain containing 1" Q5SSQ6 6 31762656-31764850 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 27.5" "Cell type enhanced" "Detected in some" "Astrocytes: 7.2;Bergmann glia: 3.1;Brain inhibitory neurons: 1.1;Choroid plexus epithelial cells: 2.4;Ependymal cells: 10.6;Microglia: 4.5;Oligodendrocyte progenitor cells: 1.7;Other brain neurons: 1.1" "Cell type enhanced" "Detected in many" "astrocyte: 9.9;ependymal cell: 11.6" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 2.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA071699 Approved "Vesicles,Cell Junctions" NA NA "Cluster 2: Non-specific - Mixed function" "Cluster 46: Brainstem - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 34: Ciliated cells - Cilia assembly & function" Vesicles "Cell Junctions" "HPA071699: " "unprognostic (1.76e-1)" "unprognostic (3.85e-1)" "unprognostic (3.81e-1)" "unprognostic (3.21e-2)" "potential prognostic favorable (2.44e-4)" "unprognostic (2.10e-1)" "unprognostic (1.10e-1)" SAPCD2 "C9orf140, p42.3" ENSG00000186193 "Suppressor APC domain containing 2" Q86UD0 9 137062127-137070557 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.8;esophagus: 8.2" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 10.6;Enteric transient amplifying cells: 25.2;Esophageal basal cells: 12.6;Gastric progenitor cells: 20.5;Megakaryocyte progenitors: 12.0;Monocyte progenitors: 41.3;Oligodendrocyte progenitor cells: 46.1;Paneth cells: 19.3" "Group enriched" "Detected in some" 8 "committed oligodendrocyte precursor: 18.8;oligodendrocyte precursor cell: 47.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Prostate - Prostate glandular cells, Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA044154 Approved Supported Nucleoplasm,Nucleoli,Cytosol NA Yes "Cluster 3: Oligodendrocytes - Myelination" "Cluster 27: Non-specific - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Cell proliferation" 14 Cytosol "Nucleoplasm, Nucleoli" "HPA044154: " "unprognostic (4.35e-3)" "unprognostic (4.72e-2)" "unprognostic (2.18e-1)" "unprognostic (2.58e-2)" "unprognostic (6.55e-2)" "unprognostic (1.54e-3)" "unprognostic (4.19e-3)" "unprognostic (1.62e-1)" "unprognostic (3.00e-1)" "potential prognostic unfavorable (2.36e-5)" "unprognostic (1.40e-3)" "potential prognostic unfavorable (1.38e-7)" "potential prognostic unfavorable (3.16e-7)" "potential prognostic unfavorable (7.66e-5)" "unprognostic (1.24e-2)" "unprognostic (1.81e-1)" "unprognostic (5.34e-3)" "unprognostic (2.05e-1)" "unprognostic (2.94e-1)" "potential prognostic unfavorable (2.59e-4)" "unprognostic (1.24e-1)" "unprognostic (1.81e-1)" "unprognostic (4.21e-1)" "unprognostic (1.43e-1)" "unprognostic (1.68e-1)" "unprognostic (1.26e-2)" "unprognostic (5.51e-1)" "unprognostic (1.51e-2)" "unprognostic (2.38e-2)" SAR1A "SAR1, Sara, SARA1" ENSG00000079332 "Secretion associated Ras related GTPase 1A" Q9NR31 10 70147289-70170523 "Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 356.4;Syncytiotrophoblasts: 308.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006923, CAB022545, HPA048368" Supported Supported "Endoplasmic reticulum" NA NA 810000 "Cluster 1: T-cells - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 21: Non-specific - Metabolism" "Cluster 52: Non-specific - Mitochondria" "Cluster 108: Fibroblasts - ECM organization" 74 "Endoplasmic reticulum" "CAB022545: , HPA006923: , HPA048368: " "unprognostic (9.16e-3)" "potential prognostic unfavorable (8.09e-4)" "unprognostic (2.88e-1)" "unprognostic (1.10e-1)" "unprognostic (4.30e-1)" "unprognostic (2.39e-2)" "unprognostic (1.47e-1)" "potential prognostic favorable (1.21e-6)" "unprognostic (3.34e-3)" "unprognostic (6.36e-3)" "unprognostic (1.95e-3)" "unprognostic (1.22e-1)" "unprognostic (2.28e-1)" "unprognostic (8.37e-3)" "unprognostic (4.94e-2)" "unprognostic (6.58e-2)" "unprognostic (3.54e-2)" "unprognostic (2.32e-2)" "unprognostic (1.72e-1)" "unprognostic (1.87e-1)" "unprognostic (1.45e-2)" "unprognostic (8.63e-3)" "unprognostic (6.68e-2)" "unprognostic (6.32e-2)" "unprognostic (2.13e-1)" "unprognostic (9.57e-2)" "unprognostic (4.21e-1)" "unprognostic (5.55e-2)" "unprognostic (1.46e-1)" "unprognostic (2.99e-2)" "unprognostic (2.35e-1)" SAR1B SARA2 ENSG00000152700 "Secretion associated Ras related GTPase 1B" Q9Y6B6 5 134601149-134649271 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 438.1;Esophageal apical cells: 336.7;Hepatocytes: 334.1;Late primary spermatocytes: 397.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006923, HPA048368" Supported Approved "Endoplasmic reticulum" NA NA 360000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 76: Non-specific - Metabolism" "Cluster 30: White matter - Myelination" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 146 "Endoplasmic reticulum" "HPA006923: , HPA048368: " "unprognostic (1.04e-1)" "unprognostic (1.86e-2)" "unprognostic (2.23e-2)" "unprognostic (1.80e-1)" "unprognostic (2.37e-2)" "unprognostic (1.45e-2)" "unprognostic (4.14e-1)" "potential prognostic unfavorable (6.15e-5)" "unprognostic (6.64e-3)" "potential prognostic unfavorable (3.03e-4)" "potential prognostic favorable (5.02e-8)" "unprognostic (2.02e-2)" "unprognostic (2.16e-1)" "unprognostic (1.76e-2)" "unprognostic (1.54e-3)" "unprognostic (3.26e-2)" "unprognostic (1.06e-1)" "unprognostic (2.60e-1)" "unprognostic (1.46e-1)" "unprognostic (1.34e-1)" "unprognostic (2.80e-2)" "unprognostic (1.56e-1)" "unprognostic (1.77e-1)" "unprognostic (1.07e-1)" "unprognostic (1.25e-1)" "unprognostic (1.78e-2)" "unprognostic (8.69e-2)" "unprognostic (5.71e-2)" "unprognostic (3.34e-2)" "unprognostic (2.68e-2)" "unprognostic (2.73e-1)" SARAF "MGC8721, TMEM66" ENSG00000133872 "Store-operated calcium entry associated regulatory factor" Q96BY9 8 30063003-30083208 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 1495.7;T-cells: 1184.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040400 Supported "Endoplasmic reticulum,Rods & Rings" NA NA 41000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 36: Brain & Liver - Signaling" "Cluster 21: Non-specific - Metabolism" "Cluster 40: Non-specific - Unknown function" "Cluster 9: T-cells - Adaptive immunity: Regulation" 107 "Endoplasmic reticulum" "Rods & Rings" "HPA040400: " "unprognostic (3.02e-2)" "unprognostic (1.22e-1)" "unprognostic (3.40e-2)" "unprognostic (3.70e-3)" "unprognostic (7.99e-2)" "unprognostic (2.56e-2)" "unprognostic (6.76e-2)" "unprognostic (2.29e-2)" "unprognostic (5.08e-2)" "validated prognostic favorable (4.88e-10)" "validated prognostic favorable (3.82e-5)" "unprognostic (1.28e-1)" "unprognostic (1.19e-1)" "unprognostic (5.20e-3)" "unprognostic (1.12e-1)" "unprognostic (7.60e-2)" "unprognostic (2.86e-1)" "unprognostic (1.31e-1)" "unprognostic (3.64e-2)" "unprognostic (9.85e-2)" "unprognostic (4.48e-2)" "unprognostic (4.08e-2)" "unprognostic (1.73e-1)" "unprognostic (1.69e-1)" "unprognostic (1.77e-1)" "unprognostic (2.57e-2)" "unprognostic (1.20e-1)" "unprognostic (3.36e-2)" "unprognostic (3.14e-2)" SARDH "DMGDHL1, SDH" ENSG00000123453 "Sarcosine dehydrogenase" Q9UL12 9 133663560-133739955 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "epididymis: 39.2;liver: 100.0;pancreas: 39.8" "Group enriched" "Detected in many" 5 "Epididymal principal cells: 116.6;Hepatocytes: 179.5;Oocytes: 96.7" "Cell type enhanced" "Detected in many" "mammillary body: 15.0" "Cancer enriched" "Detected in all" 5 "Liver Hepatocellular Carcinoma (TCGA): 41.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "memory CD4 T-cell: 3.2;naive CD4 T-cell: 6.5;T-reg: 8.5" "Lineage enriched" "Detected in single" 15 "T-cells: 8.5" "Low cancer specificity" "Detected in many" "Breast - T-cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Fibroblasts, Stomach - Chief cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "HPA057267, HPA058086" Approved Approved Mitochondria NA NA 340000 "Cluster 31: T-cells - T-cell receptor" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 59: Leukemia - T-cell receptor" "Cluster 93: Hepatocytes - Bile production & excretion" 20 Mitochondria "HPA057267: , HPA058086: " "unprognostic (6.93e-2)" "unprognostic (1.74e-1)" "unprognostic (1.46e-1)" "unprognostic (7.83e-3)" "unprognostic (4.23e-2)" "unprognostic (4.51e-2)" "unprognostic (2.18e-3)" "potential prognostic unfavorable (1.04e-4)" "unprognostic (1.21e-2)" "unprognostic (1.86e-2)" "unprognostic (1.77e-2)" "unprognostic (1.74e-2)" "unprognostic (4.18e-3)" "unprognostic (1.45e-3)" "unprognostic (1.21e-2)" "unprognostic (7.72e-2)" "unprognostic (4.04e-2)" "unprognostic (1.83e-2)" "unprognostic (4.10e-1)" "unprognostic (2.20e-1)" "unprognostic (1.36e-1)" "unprognostic (2.67e-3)" "unprognostic (2.23e-1)" "unprognostic (1.37e-1)" "unprognostic (1.62e-3)" "unprognostic (2.18e-2)" "unprognostic (5.63e-2)" "unprognostic (1.86e-1)" "unprognostic (1.08e-1)" "unprognostic (9.60e-2)" SARM1 "KIAA0524, SAMD2, SARM" ENSG00000004139 "Sterile alpha and TIR motif containing 1" Q6SZW1 17 28364356-28404049 "Enzymes, Predicted intracellular proteins" "Differentiation, Immunity, Innate immunity, Neurogenesis" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Kupffer cells: 55.3;Oligodendrocyte progenitor cells: 50.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 13.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "HPA024359, HPA024759" Uncertain Supported Mitochondria NA NA "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 72: Neuronal - Signal transduction" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 9 Mitochondria "HPA024359: , HPA024759: " "unprognostic (8.25e-2)" "unprognostic (2.19e-1)" "unprognostic (2.60e-1)" "unprognostic (1.95e-1)" "unprognostic (1.80e-1)" "unprognostic (4.21e-2)" "unprognostic (2.84e-1)" "unprognostic (1.56e-3)" "unprognostic (1.01e-1)" "potential prognostic favorable (4.94e-5)" "unprognostic (2.06e-2)" "unprognostic (5.12e-2)" "unprognostic (4.03e-1)" "unprognostic (1.17e-1)" "unprognostic (6.91e-2)" "unprognostic (1.64e-1)" "unprognostic (1.78e-1)" "unprognostic (1.12e-1)" "unprognostic (3.35e-2)" "unprognostic (1.76e-1)" "potential prognostic favorable (8.40e-5)" "unprognostic (1.52e-1)" "unprognostic (7.53e-2)" "unprognostic (1.89e-1)" "unprognostic (3.82e-2)" "unprognostic (3.20e-2)" "unprognostic (5.43e-2)" "unprognostic (9.88e-2)" "unprognostic (1.25e-1)" "unprognostic (3.77e-1)" SARNP "CIP29, Hcc-1, THO1" ENSG00000205323 "SAP domain containing ribonucleoprotein" P82979 12 55752463-55817724 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "mRNA transport, Transcription, Transcription regulation, Translation regulation, Transport" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 75.1;Microglia: 56.9;Oligodendrocytes: 59.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030902, HPA030903" Supported Supported "Nuclear speckles" NA NA 11000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 22: Non-specific - Basic cellular functions" 23 "Nuclear speckles" "HPA030902: , HPA030903: " "unprognostic (5.08e-3)" "unprognostic (4.71e-2)" "unprognostic (3.91e-1)" "potential prognostic favorable (6.42e-4)" "unprognostic (1.95e-1)" "unprognostic (1.05e-1)" "unprognostic (1.22e-1)" "unprognostic (3.50e-2)" "unprognostic (8.43e-2)" "unprognostic (1.11e-2)" "unprognostic (2.84e-3)" "unprognostic (1.94e-1)" "unprognostic (2.01e-1)" "unprognostic (1.12e-3)" "potential prognostic unfavorable (1.24e-5)" "unprognostic (1.10e-2)" "unprognostic (1.70e-3)" "unprognostic (6.10e-3)" "unprognostic (3.94e-1)" "unprognostic (4.23e-3)" "unprognostic (1.48e-1)" "unprognostic (9.32e-3)" "unprognostic (5.03e-3)" "unprognostic (7.75e-2)" "unprognostic (1.76e-1)" "unprognostic (3.60e-2)" "unprognostic (5.11e-2)" "unprognostic (1.45e-1)" "unprognostic (3.54e-1)" "unprognostic (2.49e-2)" "unprognostic (3.73e-2)" SARS1 "SARS, SERS" ENSG00000031698 "Seryl-tRNA synthetase 1" P49591 1 109213918-109238182 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis, Transcription, Transcription regulation" "Aminoacyl-tRNA synthetase, DNA-binding, Ligase" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016939, HPA064668" Approved Enhanced Cytosol NA NA 900000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 70: Non-specific - Protein processing" "Cluster 14: Neurons - Synaptic function" "Cluster 13: Non-specific - Mixed function" "Cluster 17: Non-specific - RNA processing" 28 Cytosol "HPA016939: , HPA064668: " "unprognostic (3.06e-1)" "unprognostic (2.83e-1)" "unprognostic (3.93e-1)" "unprognostic (6.36e-2)" "unprognostic (6.16e-2)" "unprognostic (1.19e-3)" "unprognostic (2.12e-2)" "unprognostic (1.34e-2)" "unprognostic (1.70e-3)" "validated prognostic favorable (9.53e-6)" "validated prognostic favorable (6.78e-5)" "unprognostic (2.42e-1)" "potential prognostic unfavorable (2.32e-4)" "unprognostic (1.80e-1)" "potential prognostic unfavorable (9.47e-4)" "unprognostic (1.36e-1)" "unprognostic (4.11e-2)" "unprognostic (2.10e-1)" "unprognostic (2.10e-1)" "unprognostic (6.36e-2)" "unprognostic (1.79e-1)" "unprognostic (1.77e-1)" "unprognostic (3.35e-2)" "unprognostic (4.42e-1)" "unprognostic (2.68e-1)" "unprognostic (2.17e-1)" "unprognostic (2.10e-1)" "unprognostic (1.25e-1)" "unprognostic (3.90e-1)" SARS2 "FLJ20450, mtSerRS, SARS, SARSM, SerRSmt, SERS, SYS" ENSG00000104835 "Seryl-tRNA synthetase 2, mitochondrial" Q9NP81 19 38915266-38930763 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 5.2;Late spermatids: 7.7;Proximal tubule cells: 5.0;Renal collecting duct intercalated cells: 5.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052730, HPA056957" Approved Uncertain Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 70: Non-specific - Protein processing" "Cluster 14: Neurons - Synaptic function" "Cluster 4: Non-specific - Transcription" "Cluster 102: Non-specific - Mixed function" 11 "Nucleoplasm, Mitochondria" Vesicles "HPA052730: , HPA056957: " "unprognostic (1.17e-1)" "unprognostic (1.10e-2)" "unprognostic (2.04e-1)" "unprognostic (1.62e-1)" "unprognostic (2.33e-2)" "unprognostic (3.27e-3)" "unprognostic (1.60e-1)" "unprognostic (2.73e-2)" "unprognostic (7.76e-2)" "unprognostic (3.88e-3)" "unprognostic (3.00e-2)" "unprognostic (8.45e-2)" "unprognostic (9.97e-3)" "unprognostic (4.96e-3)" "unprognostic (3.05e-1)" "unprognostic (3.44e-2)" "unprognostic (1.14e-1)" "unprognostic (1.69e-1)" "unprognostic (2.97e-1)" "unprognostic (1.24e-2)" "unprognostic (1.02e-1)" "unprognostic (4.82e-2)" "unprognostic (4.96e-2)" "unprognostic (2.19e-1)" "unprognostic (2.00e-2)" "unprognostic (1.76e-1)" "unprognostic (8.48e-2)" "unprognostic (2.38e-1)" "unprognostic (1.49e-1)" "unprognostic (1.70e-1)" "unprognostic (3.71e-1)" SART1 "Ara1, HAF, SNRNP110, Snu66" ENSG00000175467 "Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP" O43290 11 65961728-65980137 "Cancer-related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Allergen, Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031188, HPA031189, HPA031190" Supported Enhanced "Nuclear speckles,Golgi apparatus" NA NA 140000 "Cluster 45: Eosinophils - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 24: Non-specific - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" 127 "Nuclear speckles" "Golgi apparatus" "HPA031188: , HPA031189: , HPA031190: " "unprognostic (3.58e-3)" "unprognostic (9.41e-2)" "unprognostic (1.26e-1)" "unprognostic (2.15e-2)" "unprognostic (1.46e-1)" "unprognostic (4.63e-2)" "unprognostic (9.20e-2)" "unprognostic (7.81e-2)" "unprognostic (1.98e-2)" "unprognostic (1.08e-2)" "unprognostic (1.56e-2)" "unprognostic (1.03e-1)" "unprognostic (1.41e-1)" "unprognostic (1.01e-3)" "unprognostic (1.63e-2)" "unprognostic (4.71e-2)" "unprognostic (9.84e-3)" "unprognostic (1.95e-1)" "unprognostic (1.57e-1)" "unprognostic (4.65e-2)" "unprognostic (2.71e-3)" "unprognostic (3.94e-2)" "unprognostic (3.22e-2)" "unprognostic (2.18e-2)" "unprognostic (1.86e-1)" "unprognostic (1.53e-1)" "unprognostic (2.26e-1)" "unprognostic (9.11e-2)" "unprognostic (2.07e-1)" "unprognostic (4.85e-2)" "unprognostic (1.11e-1)" SART3 "KIAA0156, p110, RP11-13G14, TIP110" ENSG00000075856 "Spliceosome associated factor 3, U4/U6 recycling protein" Q15020 12 108522214-108561400 "Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028840, HPA044322" Approved Supported Nucleoplasm No No 8100 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 49: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 119 Nucleoplasm "HPA028840: , HPA044322: " "unprognostic (1.90e-2)" "unprognostic (2.22e-2)" "unprognostic (2.16e-1)" "unprognostic (1.38e-1)" "unprognostic (2.15e-1)" "unprognostic (3.80e-3)" "unprognostic (3.30e-1)" "potential prognostic favorable (9.29e-5)" "unprognostic (1.41e-1)" "unprognostic (2.05e-2)" "unprognostic (6.04e-2)" "unprognostic (7.91e-3)" "unprognostic (1.60e-1)" "potential prognostic unfavorable (2.69e-4)" "unprognostic (2.26e-2)" "unprognostic (1.16e-2)" "unprognostic (4.41e-2)" "unprognostic (1.43e-1)" "unprognostic (4.54e-3)" "unprognostic (8.61e-2)" "unprognostic (1.40e-2)" "unprognostic (2.40e-1)" "unprognostic (4.68e-3)" "unprognostic (5.25e-2)" "unprognostic (9.20e-2)" "unprognostic (4.73e-2)" "unprognostic (9.14e-2)" "unprognostic (1.23e-1)" "unprognostic (2.09e-1)" "unprognostic (4.86e-2)" "unprognostic (3.57e-1)" SASH1 "dJ323M4.1, KIAA0790, SH3D6A" ENSG00000111961 "SAM and SH3 domain containing 1" O94885 6 148272304-148552044 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Hypotrichosis, Palmoplantar keratoderma, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 730.4;Esophageal apical cells: 1790.7;Extravillous trophoblasts: 715.2;Lymphatic endothelial cells: 697.6;Vascular endothelial cells: 691.4" "Cell type enhanced" "Detected in all" "astrocyte: 873.5;fibroblast: 1017.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 16 "classical monocyte: 1.1;intermediate monocyte: 2.4;non-classical monocyte: 1.2" "Lineage enriched" "Detected in single" 25 "monocytes: 2.4" "Cancer enhanced" "Detected in many" "skin cancer: 40.7" "Adrenal gland - Endothelial cells, Lung - Endothelial cells, Prostate - Endothelial cells, Spleen - Macrophages, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029947, HPA029949" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 19: Astrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 16 "Nucleoplasm, Cytosol" "HPA029947: , HPA029949: " "unprognostic (6.29e-2)" "unprognostic (5.12e-2)" "unprognostic (1.74e-1)" "unprognostic (2.05e-1)" "unprognostic (1.30e-1)" "unprognostic (6.32e-2)" "unprognostic (1.96e-2)" "unprognostic (2.19e-2)" "unprognostic (7.91e-3)" "unprognostic (3.82e-2)" "validated prognostic favorable (2.09e-9)" "validated prognostic favorable (1.26e-5)" "unprognostic (1.28e-1)" "unprognostic (8.24e-2)" "unprognostic (3.66e-2)" "unprognostic (2.11e-2)" "unprognostic (3.49e-1)" "unprognostic (1.47e-1)" "unprognostic (1.85e-1)" "potential prognostic unfavorable (8.07e-5)" "unprognostic (1.12e-1)" "unprognostic (1.86e-1)" "unprognostic (1.96e-1)" "unprognostic (3.33e-1)" "unprognostic (8.52e-2)" "unprognostic (4.02e-2)" "unprognostic (1.13e-1)" "unprognostic (8.85e-2)" "unprognostic (5.69e-2)" "unprognostic (8.32e-2)" "unprognostic (6.56e-3)" SASH3 "753P9, CXorf9, HACS2, SH3D6C, SLY" ENSG00000122122 "SAM and SH3 domain containing 3" O75995 X 129779949-129795201 "Disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 102.1;intestine: 34.2;lymphoid tissue: 112.8" "Cell type enhanced" "Detected in some" "B-cells: 60.5;cDC: 31.7;Hofbauer cells: 53.5;Innate lymphoid cells: 29.4;Kupffer cells: 32.8;Macrophages: 30.1;Microglia: 44.6;Monocyte progenitors: 45.3;monocytes: 66.2;Neutrophil progenitors: 97.2;Neutrophils: 193.4;NK-cells: 80.2;pDCs: 27.3;Plasma cells: 27.5;T-cells: 43.8;Thymocytes: 88.1" "Group enriched" "Detected in some" 157 "central nervous system macrophage: 51.7;leukocyte: 82.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Leukemia: 109.7;lymphoma: 119.2" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Skeletal muscle - Macrophages, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA001085 Enhanced Approved "Nucleoplasm,Nuclear bodies,Plasma membrane" NA NA 6900 "Cluster 25: Non-specific - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 29: Neutrophils - Innate immune cellular maintenance" "Plasma membrane" "Nucleoplasm, Nuclear bodies" "HPA001085: " "unprognostic (2.99e-2)" "unprognostic (8.80e-3)" "unprognostic (1.54e-3)" "unprognostic (5.28e-2)" "unprognostic (7.17e-2)" "unprognostic (2.59e-1)" "unprognostic (1.08e-1)" "unprognostic (1.46e-1)" "unprognostic (1.89e-3)" "unprognostic (4.24e-1)" "unprognostic (2.02e-1)" "unprognostic (3.88e-1)" "unprognostic (4.92e-2)" "unprognostic (1.74e-1)" "unprognostic (3.44e-2)" "potential prognostic favorable (1.18e-4)" "unprognostic (2.39e-2)" "unprognostic (1.75e-1)" "unprognostic (2.32e-1)" "unprognostic (2.24e-1)" "unprognostic (2.96e-1)" "unprognostic (5.35e-2)" "unprognostic (3.23e-2)" "unprognostic (6.93e-2)" "unprognostic (6.07e-2)" "unprognostic (8.93e-2)" "unprognostic (7.46e-2)" "unprognostic (3.18e-1)" "unprognostic (2.76e-2)" "unprognostic (6.62e-2)" "unprognostic (1.77e-1)" SASS6 "DKFZp761A078, FLJ22097, SAS-6, SAS6" ENSG00000156876 "SAS-6 centriolar assembly protein" Q6UVJ0 1 100083563-100132955 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Cell cycle" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 84.6;Erythrocyte progenitors: 67.1;Oocytes: 188.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.9" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 42.0" "Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028187 Uncertain Approved "Vesicles,Primary cilium,Cytosol" NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 25: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 27: Non-specific - Cell proliferation" 37 "Primary cilium, Cytosol" Vesicles "HPA028187: " "unprognostic (1.31e-2)" "unprognostic (6.00e-2)" "unprognostic (1.03e-1)" "unprognostic (1.29e-1)" "unprognostic (6.08e-2)" "unprognostic (1.68e-1)" "unprognostic (1.77e-1)" "unprognostic (1.16e-1)" "unprognostic (2.60e-2)" "unprognostic (2.49e-1)" "unprognostic (2.33e-1)" "unprognostic (5.55e-2)" "validated prognostic unfavorable (6.95e-5)" "validated prognostic unfavorable (7.41e-5)" "potential prognostic unfavorable (1.08e-4)" "unprognostic (1.59e-2)" "unprognostic (6.25e-3)" "unprognostic (3.97e-2)" "unprognostic (6.66e-2)" "unprognostic (1.13e-1)" "unprognostic (7.09e-2)" "unprognostic (1.26e-3)" "unprognostic (2.28e-2)" "unprognostic (4.00e-2)" "unprognostic (2.85e-2)" "unprognostic (5.16e-2)" "unprognostic (1.05e-2)" "unprognostic (2.75e-1)" "unprognostic (8.01e-2)" "unprognostic (1.35e-1)" SAT1 "SAT, SSAT" ENSG00000130066 "Spermidine/spermine N1-acetyltransferase 1" P21673 X 23783173-23786210 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "cDC: 5324.4;Endometrial glandular cells: 5635.5;Endometrial luminal cells: 5738.0;Epididymal basal cells: 11105.2;Esophageal apical cells: 4458.9;Kupffer cells: 6462.1;monocytes: 4543.8;Neutrophils: 8489.6;Ocular epithelial cells: 4606.9" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 732.5;endothelial cell: 651.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 654.2;intermediate monocyte: 1845.7;neutrophil: 1585.1;non-classical monocyte: 2462.2" "Group enriched" "Detected in all" 6 "granulocytes: 1585.1;monocytes: 2462.2" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB047343, HPA055312, CAB069914" Supported NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 28: Liver & Adrenal gland - Secretion" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 49 "CAB047343: , CAB069914: , HPA055312: " "unprognostic (7.13e-2)" "unprognostic (4.54e-2)" "unprognostic (3.17e-2)" "unprognostic (1.04e-1)" "unprognostic (8.37e-2)" "unprognostic (1.19e-1)" "unprognostic (1.63e-2)" "unprognostic (2.14e-1)" "unprognostic (1.81e-1)" "unprognostic (1.70e-1)" "unprognostic (1.45e-1)" "unprognostic (2.54e-1)" "unprognostic (4.61e-2)" "unprognostic (1.86e-2)" "unprognostic (1.80e-2)" "unprognostic (9.32e-2)" "unprognostic (4.40e-2)" "unprognostic (4.58e-2)" "unprognostic (1.29e-1)" "unprognostic (1.88e-1)" "unprognostic (1.14e-2)" "unprognostic (1.45e-3)" "unprognostic (1.76e-1)" "unprognostic (1.32e-1)" "unprognostic (7.24e-2)" "unprognostic (4.29e-3)" "unprognostic (2.66e-1)" "unprognostic (6.92e-2)" "unprognostic (3.38e-2)" "unprognostic (3.93e-2)" "unprognostic (9.53e-2)" SAT2 SSAT2 ENSG00000141504 "Spermidine/spermine N1-acetyltransferase family member 2" Q96F10 17 7626234-7627876 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 968.3;Hepatocytes: 327.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022136, HPA057096" Enhanced NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 42: Non-specific - Unknown function" "Cluster 1: Enterocytes - Absorption and Digestion" 6 "HPA022136: , HPA057096: " "unprognostic (1.09e-1)" "unprognostic (9.86e-3)" "unprognostic (2.33e-1)" "unprognostic (7.35e-3)" "unprognostic (3.09e-1)" "unprognostic (6.61e-2)" "unprognostic (1.70e-2)" "unprognostic (4.45e-2)" "unprognostic (5.39e-3)" "unprognostic (3.32e-2)" "potential prognostic favorable (1.16e-4)" "unprognostic (2.07e-1)" "unprognostic (9.88e-2)" "unprognostic (1.78e-2)" "unprognostic (2.68e-3)" "unprognostic (2.13e-2)" "unprognostic (2.27e-1)" "unprognostic (2.11e-1)" "unprognostic (2.76e-1)" "unprognostic (4.53e-2)" "unprognostic (1.10e-1)" "unprognostic (1.95e-3)" "unprognostic (3.34e-2)" "unprognostic (1.79e-1)" "unprognostic (1.98e-1)" "unprognostic (1.68e-1)" "potential prognostic unfavorable (9.32e-4)" "unprognostic (2.93e-2)" "unprognostic (1.80e-1)" "unprognostic (5.00e-2)" "unprognostic (2.20e-1)" SATB1 ENSG00000182568 "SATB homeobox 1" Q01826 3 18345377-18445621 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Repressor" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "lymphoid tissue: 346.3;skeletal muscle: 89.7" "Cell type enhanced" "Detected in many" "Innate lymphoid cells: 398.1;NK-cells: 221.6;T-cells: 227.6;Thymocytes: 393.0" "Cell type enhanced" "Detected in all" "deep-layer near-projecting: 538.4;MGE interneuron: 475.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "naive CD4 T-cell: 104.8" "Group enriched" "Detected in all" 4 "NK-cells: 61.0;T-cells: 104.8" "Cancer enhanced" "Detected in many" "Leukemia: 62.3;Neuroblastoma: 56.1" "Adipose visceral - T-cells, Skeletal muscle - Skeletal myocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051769, CAB056144, HPA070534" Enhanced Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 80: Thymus - Adaptive immune response" "Cluster 53: Neurons - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 9: T-cells - Adaptive immunity: Regulation" 37 Nucleoplasm "Nuclear bodies" "CAB056144: , HPA051769: , HPA070534: " "potential prognostic favorable (3.89e-4)" "unprognostic (1.34e-1)" "unprognostic (6.34e-2)" "unprognostic (4.27e-1)" "unprognostic (4.98e-2)" "unprognostic (1.54e-1)" "unprognostic (3.55e-2)" "unprognostic (1.15e-3)" "unprognostic (5.17e-3)" "unprognostic (2.65e-3)" "potential prognostic favorable (2.31e-4)" "unprognostic (4.37e-2)" "unprognostic (5.74e-3)" "unprognostic (1.60e-1)" "unprognostic (1.15e-2)" "unprognostic (1.82e-2)" "unprognostic (3.44e-1)" "unprognostic (7.93e-2)" "unprognostic (4.96e-1)" "unprognostic (3.52e-2)" "unprognostic (9.96e-2)" "unprognostic (3.54e-2)" "unprognostic (2.01e-2)" "unprognostic (5.63e-2)" "unprognostic (2.75e-1)" "unprognostic (2.32e-1)" "unprognostic (1.14e-1)" "unprognostic (1.21e-2)" "unprognostic (1.34e-1)" "unprognostic (2.95e-2)" "unprognostic (5.76e-2)" SATB2 "FLJ21474, KIAA1034" ENSG00000119042 "SATB homeobox 2" Q9UPW6 2 199269505-199471266 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, Developmental protein, DNA-binding, Repressor" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 13.1;intestine: 30.8" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 139.5;Choroid plexus epithelial cells: 401.8;Colonocytes: 500.6;Enteric stem cells: 319.3;Enteric transient amplifying cells: 273.7;Ependymal cells: 185.6;Goblet cells: 280.1;Neuroendocrine cells: 239.7;Tuft cells: 403.5" "Group enriched" "Detected in many" 4 "choroid plexus epithelial cell: 419.4;deep-layer corticothalamic and 6b: 493.3;deep-layer intratelencephalic: 540.6;deep-layer near-projecting: 363.5;ependymal cell: 195.2;hippocampal CA1-3: 296.1;miscellaneous: 439.0;upper-layer intratelencephalic: 516.6" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 30.7;Rectum Adenocarcinoma (TCGA): 32.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Region enhanced" "Detected in many" "cerebral cortex: 29.2" "Group enriched" "Detected in all" 5 "cerebral cortex: 64.0;hippocampal formation: 51.0" "HPA001042, CAB023669, HPA029543, CAB062562, CAB067751, CAB068229, CAB068230, CAB068231" Enhanced Supported "Nucleoplasm,Centrosome,Basal body,Cytosol" NA NA "Cluster 17: Intestine - Digestion" "Cluster 53: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 24 Nucleoplasm "Centrosome, Basal body, Cytosol" "CAB023669: , CAB062562: , CAB067751: , CAB068229: , CAB068230: , CAB068231: , HPA001042: , HPA029543: " "unprognostic (8.56e-3)" "unprognostic (4.78e-2)" "unprognostic (2.08e-2)" "unprognostic (7.84e-2)" "unprognostic (1.76e-1)" "unprognostic (1.41e-3)" "unprognostic (7.22e-2)" "unprognostic (1.49e-1)" "unprognostic (1.25e-2)" "potential prognostic favorable (8.56e-8)" "unprognostic (1.71e-3)" "potential prognostic favorable (7.31e-4)" "unprognostic (8.29e-2)" "unprognostic (1.65e-2)" "potential prognostic unfavorable (7.87e-5)" "unprognostic (5.28e-2)" "unprognostic (1.93e-1)" "unprognostic (1.18e-1)" "unprognostic (6.37e-2)" "unprognostic (3.45e-2)" "unprognostic (1.67e-1)" "unprognostic (8.43e-2)" "unprognostic (1.56e-1)" "unprognostic (3.67e-2)" "unprognostic (8.59e-2)" "unprognostic (2.36e-1)" "unprognostic (2.12e-1)" SATL1 ENSG00000184788 "Spermidine/spermine N1-acetyl transferase like 1" Q86VE3 X 85092284-85243911 "Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "Bergmann glia: 16.3;Brain excitatory neurons: 13.9;Brain inhibitory neurons: 13.9;Cardiomyocytes: 21.0;Early primary spermatocytes: 12.7;Ependymal cells: 12.3;Lactotrophs: 17.4;Late spermatids: 28.5;Other brain neurons: 12.9;Retinal amacrine cells: 14.7;Sertoli cells: 28.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Prostate Adenocarcinoma (TCGA): 1.0;Uterine Corpus Endometrial Carcinoma (TCGA): 1.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adrenal gland - Adrenal cortex cells, Pituitary gland - Lactotropes" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA060369 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 53: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" Nucleoplasm Cytosol "HPA060369: " "unprognostic (4.40e-2)" "potential prognostic favorable (5.27e-5)" "unprognostic (1.06e-1)" "unprognostic (3.02e-2)" "unprognostic (8.00e-2)" SAV1 "salvador, WW45, WWP4" ENSG00000151748 "Salvador family WW domain containing protein 1" Q9H4B6 14 50632058-50668306 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Platelets: 230.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Pituitary gland - Endothelial cells, Skin - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001808 Approved Supported Cytosol NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 55: Breast - Lactation" "Cluster 11: White matter - Signal transduction" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 39 Cytosol "HPA001808: " "unprognostic (2.62e-1)" "potential prognostic favorable (6.99e-4)" "unprognostic (1.87e-1)" "unprognostic (7.81e-3)" "unprognostic (1.25e-1)" "unprognostic (1.00e-3)" "unprognostic (2.69e-1)" "unprognostic (1.96e-1)" "unprognostic (1.96e-1)" "unprognostic (7.90e-2)" "validated prognostic favorable (4.07e-7)" "validated prognostic favorable (1.27e-5)" "unprognostic (6.99e-2)" "unprognostic (3.73e-3)" "unprognostic (3.38e-2)" "unprognostic (4.70e-2)" "unprognostic (1.24e-3)" "unprognostic (3.23e-2)" "unprognostic (2.93e-1)" "unprognostic (1.40e-2)" "unprognostic (7.40e-3)" "potential prognostic unfavorable (6.49e-5)" "unprognostic (2.89e-3)" "unprognostic (1.30e-1)" "unprognostic (2.57e-1)" "unprognostic (2.95e-2)" "unprognostic (1.92e-1)" "unprognostic (1.53e-1)" "unprognostic (2.96e-1)" "unprognostic (2.45e-2)" "unprognostic (1.51e-1)" SAXO1 "C9orf138, FAM154A, MGC35182" ENSG00000155875 "Stabilizer of axonemal microtubules 1" Q8IYX7 9 18858906-19049358 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 93 "testis: 35.8" "Group enriched" "Detected in many" 6 "Early spermatids: 885.9;Late primary spermatocytes: 238.4" "Cell type enhanced" "Detected in all" "Bergmann glia: 82.3;ependymal cell: 87.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA023899, HPA076454" Enhanced Supported "Flagellar centriole,Mid piece,End piece" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 17: Choroid plexus - Cilium" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 39 "Flagellar centriole, End piece" "Mid piece" "HPA023899: , HPA076454: " SAXO2 "DKFZp666G057, FAM154B" ENSG00000188659 "Stabilizer of axonemal microtubules 2" Q658L1 15 82262810-82284930 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "epididymis: 16.7;fallopian tube: 48.1;testis: 18.6" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 117.0;Ependymal cells: 120.8;Fallopian tube ciliated cells: 293.4;Late primary spermatocytes: 120.9;Late spermatids: 258.9;Respiratory ciliated cells: 639.3" "Cell type enhanced" "Detected in all" "ependymal cell: 139.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040487, HPA040833" Enhanced Approved "Centrosome,Cytosol,Connecting piece,Mid piece" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 11: Neuronal - Sensory perception" "Cluster 107: Ciliated cells - Cilia assembly & function" 2 "Centrosome, Cytosol, Connecting piece" "Mid piece" "HPA040487: , HPA040833: " "unprognostic (7.17e-3)" "unprognostic (1.33e-1)" "unprognostic (2.72e-2)" "unprognostic (1.19e-2)" "unprognostic (1.42e-1)" "unprognostic (4.45e-2)" "unprognostic (3.47e-1)" "unprognostic (7.12e-3)" "unprognostic (4.33e-2)" "unprognostic (1.36e-1)" "unprognostic (3.81e-2)" "unprognostic (2.34e-2)" "unprognostic (2.91e-1)" "unprognostic (3.88e-3)" "unprognostic (1.40e-1)" "unprognostic (1.09e-1)" "unprognostic (1.16e-2)" "unprognostic (1.94e-1)" "unprognostic (2.66e-1)" "unprognostic (3.25e-1)" "unprognostic (1.07e-1)" "unprognostic (1.38e-1)" "unprognostic (4.62e-2)" "unprognostic (4.91e-3)" "unprognostic (6.87e-2)" SAYSD1 "C6orf64, FLJ11101" ENSG00000112167 "SAYSVFN motif domain containing 1" Q9NPB0 6 39104063-39115193 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 30.6" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 86.4;Early spermatids: 109.4;Late primary spermatocytes: 427.7;Late spermatids: 80.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007959 Approved Supported Vesicles NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 67: Testis - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 10 Vesicles "HPA007959: " "unprognostic (1.59e-1)" "unprognostic (3.40e-2)" "unprognostic (4.31e-2)" "unprognostic (9.97e-2)" "unprognostic (2.71e-1)" "unprognostic (2.47e-1)" "potential prognostic favorable (4.95e-4)" "unprognostic (2.29e-1)" "unprognostic (1.05e-1)" "unprognostic (7.72e-3)" "unprognostic (2.58e-3)" "unprognostic (1.43e-1)" "potential prognostic unfavorable (6.78e-4)" "unprognostic (2.71e-1)" "unprognostic (1.10e-1)" "unprognostic (1.38e-2)" "unprognostic (3.02e-1)" "potential prognostic favorable (8.05e-4)" "unprognostic (2.86e-1)" "unprognostic (9.38e-3)" "unprognostic (6.82e-2)" "unprognostic (1.14e-1)" "unprognostic (6.38e-3)" "unprognostic (4.35e-1)" "unprognostic (1.04e-2)" "unprognostic (3.45e-2)" "unprognostic (8.39e-3)" "unprognostic (2.13e-1)" "unprognostic (4.28e-1)" SBDS "CGI-97, FLJ10917, SDO1, SDS, SWDS" ENSG00000126524 "SBDS ribosome maturation factor" Q9Y3A5 7 66987680-66995693 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Ribosome biogenesis" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 699.4;Esophageal apical cells: 765.9;Late spermatids: 2814.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028891 Approved Supported Nucleoplasm,Cytosol NA NA 18000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 41 Cytosol Nucleoplasm "HPA028891: " "unprognostic (1.53e-1)" "potential prognostic unfavorable (1.82e-4)" "unprognostic (1.83e-1)" "unprognostic (8.71e-2)" "unprognostic (6.69e-2)" "unprognostic (9.18e-2)" "unprognostic (5.26e-2)" "potential prognostic unfavorable (5.67e-5)" "unprognostic (3.34e-3)" "unprognostic (3.14e-2)" "validated prognostic favorable (7.98e-7)" "validated prognostic favorable (6.53e-4)" "unprognostic (1.61e-1)" "unprognostic (1.66e-1)" "unprognostic (1.53e-2)" "unprognostic (9.68e-3)" "unprognostic (9.82e-2)" "unprognostic (2.35e-1)" "unprognostic (5.33e-3)" "unprognostic (4.36e-3)" "unprognostic (5.95e-2)" "unprognostic (9.73e-2)" "unprognostic (1.60e-1)" "unprognostic (2.46e-1)" "unprognostic (9.09e-2)" "unprognostic (2.14e-1)" "unprognostic (1.18e-1)" "unprognostic (2.42e-3)" "unprognostic (1.41e-1)" "unprognostic (1.14e-1)" "unprognostic (9.21e-2)" SBF1 "DENND7A, MTMR5" ENSG00000100241 "SET binding factor 1" O95248 22 50443219-50483923 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074004 Supported "Nuclear bodies" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 78: Brain - Neuronal signaling" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 21 "Nuclear bodies" "HPA074004: " "unprognostic (2.30e-2)" "unprognostic (1.10e-1)" "unprognostic (1.03e-3)" "unprognostic (1.36e-1)" "unprognostic (9.59e-2)" "unprognostic (2.07e-2)" "unprognostic (1.13e-1)" "unprognostic (4.07e-2)" "unprognostic (6.90e-3)" "unprognostic (2.11e-1)" "unprognostic (1.08e-1)" "unprognostic (1.18e-1)" "potential prognostic favorable (1.83e-4)" "potential prognostic unfavorable (4.57e-4)" "unprognostic (5.59e-2)" "unprognostic (2.01e-1)" "unprognostic (1.22e-1)" "unprognostic (1.06e-1)" "unprognostic (1.42e-1)" "unprognostic (5.51e-2)" "unprognostic (3.69e-2)" "unprognostic (1.42e-1)" "unprognostic (5.93e-2)" "unprognostic (6.88e-2)" "unprognostic (2.22e-1)" "unprognostic (1.06e-1)" "unprognostic (1.14e-1)" "unprognostic (8.57e-2)" "unprognostic (2.07e-2)" "unprognostic (5.23e-3)" "unprognostic (6.27e-2)" SBF2 "CMT4B2, DENND7B, KIAA1766, MTMR13" ENSG00000133812 "SET binding factor 2" Q86WG5 11 9776776-10304877 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Autophagy "Guanine-nucleotide releasing factor" "Charcot-Marie-Tooth disease, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Neutrophils: 1986.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 3.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050933 Uncertain Approved "Nucleoplasm,Intermediate filaments,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" 11 Nucleoplasm "Intermediate filaments, Cytosol" "HPA050933: " "unprognostic (1.36e-1)" "unprognostic (2.09e-1)" "unprognostic (6.90e-3)" "unprognostic (1.76e-3)" "unprognostic (2.19e-1)" "unprognostic (2.25e-1)" "unprognostic (1.95e-1)" "unprognostic (6.67e-2)" "unprognostic (5.16e-2)" "unprognostic (4.27e-2)" "potential prognostic favorable (1.30e-6)" "unprognostic (1.33e-3)" "unprognostic (1.20e-1)" "unprognostic (1.02e-1)" "unprognostic (6.20e-3)" "unprognostic (1.02e-2)" "unprognostic (2.30e-1)" "unprognostic (1.10e-1)" "unprognostic (2.24e-1)" "unprognostic (1.85e-2)" "unprognostic (4.47e-2)" "unprognostic (2.06e-3)" "unprognostic (8.09e-3)" "unprognostic (2.71e-1)" "unprognostic (1.07e-2)" "unprognostic (8.21e-2)" "unprognostic (5.00e-2)" "unprognostic (1.47e-1)" "unprognostic (2.90e-1)" "unprognostic (1.79e-1)" "unprognostic (3.22e-3)" SBK1 Sbk ENSG00000188322 "SH3 domain binding kinase 1" Q52WX2 16 28259246-28323849 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 43.0;skeletal muscle: 41.1" "Cell type enriched" "Detected in many" 4 "Myonuclei: 218.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 1.5" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Neuroblastoma: 32.1" "Breast - Breast glandular cells, Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Skeletal myocytes, Thyroid gland - Thyroid glandular cells" "Region enriched" "Detected in all" 5 "cerebellum: 275.9" "Low region specificity" "Detected in all" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 15: Non-specific - Transcription" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" "unprognostic (2.42e-2)" "unprognostic (9.52e-2)" "unprognostic (2.08e-1)" "unprognostic (1.06e-2)" "unprognostic (2.49e-1)" "unprognostic (1.58e-2)" "unprognostic (6.40e-2)" "potential prognostic favorable (7.78e-5)" "unprognostic (4.44e-2)" "unprognostic (2.62e-1)" "unprognostic (1.67e-3)" "unprognostic (5.81e-3)" "unprognostic (7.77e-2)" "unprognostic (9.91e-2)" "unprognostic (2.01e-3)" "unprognostic (4.34e-2)" "unprognostic (2.03e-1)" "unprognostic (6.92e-3)" "unprognostic (1.46e-1)" "unprognostic (3.49e-1)" "unprognostic (1.29e-2)" "unprognostic (3.40e-1)" "unprognostic (1.04e-1)" "unprognostic (1.70e-1)" "unprognostic (4.93e-2)" "unprognostic (4.04e-2)" SBK2 SGK069 ENSG00000187550 "SH3 domain binding kinase family member 2" P0C263 19 55528611-55537133 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "heart muscle: 122.0" "Group enriched" "Detected in some" 9 "Early spermatids: 8.6;Epicardial cells: 2.3;Late spermatids: 8.6;Pancreatic islet cells: 3.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Sarcoma: 10.6" "Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA030631 Uncertain NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" "HPA030631: " "unprognostic (3.37e-1)" "unprognostic (2.92e-2)" "unprognostic (2.39e-2)" "unprognostic (9.68e-2)" SBK3 SgK110 ENSG00000231274 "SH3 domain binding kinase family member 3" P0C264 19 55540656-55545543 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 30.5;tongue: 14.1" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 2.2;Thymic myoid cells: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Adrenocortical cancer: 3.3" "Breast - Endothelial cells, Heart muscle - Cardiomyocytes" "Not detected" "Not detected" HPA078322 Approved Mitochondria NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 9 Mitochondria "HPA078322: " SBNO1 "FLJ10701, FLJ10833, MOP3, Sno" ENSG00000139697 "Strawberry notch homolog 1" A3KN83 12 123289109-123364847 "Essential proteins, Predicted intracellular proteins" "Inflammatory response, Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 35.2" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 367.6;Neutrophils: 294.5;Undifferentiated spermatogonia: 325.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042388 Approved Approved Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 34: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" Nucleoplasm "HPA042388: " "unprognostic (1.34e-1)" "unprognostic (2.45e-3)" "unprognostic (4.57e-1)" "unprognostic (1.04e-2)" "unprognostic (8.09e-2)" "unprognostic (5.44e-2)" "unprognostic (3.38e-1)" "unprognostic (5.87e-2)" "unprognostic (1.70e-1)" "unprognostic (2.94e-3)" "potential prognostic favorable (2.02e-4)" "unprognostic (1.04e-2)" "unprognostic (3.49e-1)" "unprognostic (4.39e-3)" "unprognostic (5.13e-2)" "unprognostic (1.16e-2)" "potential prognostic unfavorable (1.01e-4)" "unprognostic (1.69e-1)" "unprognostic (1.40e-2)" "unprognostic (7.94e-2)" "unprognostic (1.09e-1)" "unprognostic (3.08e-1)" "unprognostic (3.24e-1)" "unprognostic (6.94e-2)" "unprognostic (1.16e-2)" "unprognostic (9.63e-2)" "unprognostic (2.45e-1)" "unprognostic (7.36e-2)" "unprognostic (4.37e-1)" "unprognostic (1.00e-1)" "unprognostic (1.48e-1)" SBNO2 "FLJ00173, KIAA0963, Sno, Stno" ENSG00000064932 "Strawberry notch homolog 2" Q9Y2G9 19 1107637-1174268 "Predicted intracellular proteins" "Differentiation, Osteogenesis, Transcription, Transcription regulation" "Activator, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Epicardial cells: 127.4;Papillary tip epithelial cells: 52.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "neutrophil: 2.5" "Lineage enriched" "Detected in single" 8 "granulocytes: 2.5" "Low cancer specificity" "Detected in all" "Colon - Neutrophils, Liver - Neutrophils, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041867 Approved NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 23: Non-specific - Transcription" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 1 "HPA041867: " "unprognostic (3.47e-2)" "unprognostic (1.70e-1)" "unprognostic (3.84e-3)" "unprognostic (1.91e-3)" "unprognostic (1.77e-1)" "unprognostic (3.04e-2)" "unprognostic (1.77e-1)" "unprognostic (3.03e-3)" "unprognostic (6.38e-3)" "unprognostic (9.91e-3)" "potential prognostic unfavorable (3.37e-4)" "unprognostic (3.24e-1)" "unprognostic (1.60e-3)" "unprognostic (4.97e-2)" "unprognostic (5.01e-2)" "unprognostic (2.32e-2)" "unprognostic (1.52e-1)" "potential prognostic unfavorable (7.41e-4)" "unprognostic (1.48e-1)" "unprognostic (2.21e-3)" "unprognostic (2.90e-1)" "unprognostic (3.17e-1)" "unprognostic (1.28e-3)" "unprognostic (1.34e-1)" "unprognostic (9.60e-2)" "unprognostic (1.46e-1)" "unprognostic (2.32e-1)" "unprognostic (9.40e-3)" "unprognostic (3.08e-1)" "unprognostic (5.40e-3)" "unprognostic (3.30e-2)" SBSN "HLAR698, UNQ698" ENSG00000189001 Suprabasin Q6UWP8 19 35523367-35528351 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 628.8;esophagus: 1012.5;skin 1: 2318.1;vagina: 717.4" "Cell type enriched" "Detected in some" 4 "Esophageal apical cells: 13875.4" "Cell type enhanced" "Detected in single" "medium spiny neuron: 1.3" "Group enriched" "Detected in many" 6 "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 222.2;Head and Neck Squamous Cell Carcinoma (TCGA): 781.2;Skin Cutaneous Melanoma (TCGA): 392.4" "Region enriched" "Detected in some" 7 "basal ganglia: 7.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Bone cancer: 38.8;head and neck cancer: 19.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062568, HPA067734" Enhanced Approved Vesicles "Secreted - unknown location" "No annotated function" NA NA 120000000 "Cluster 58: Skin - Keratinization" "Cluster 33: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 2 Vesicles "HPA062568: , HPA067734: " "unprognostic (2.50e-1)" "unprognostic (1.55e-1)" "unprognostic (1.01e-2)" "unprognostic (1.18e-1)" "unprognostic (2.90e-2)" "potential prognostic unfavorable (2.62e-4)" "unprognostic (6.40e-2)" "potential prognostic unfavorable (2.72e-4)" "unprognostic (4.25e-2)" "unprognostic (2.90e-1)" "unprognostic (3.43e-1)" "unprognostic (1.65e-3)" "unprognostic (2.71e-1)" "unprognostic (3.72e-2)" "unprognostic (3.21e-2)" "unprognostic (1.93e-1)" "unprognostic (1.78e-1)" SBSPON "C8orf84, RPESP" ENSG00000164764 "Somatomedin B and thrombospondin type 1 domain containing" Q8IVN8 8 73064543-73124088 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 21.4" "Cell type enhanced" "Detected in many" "Epididymal efferent duct absorptive cells: 71.5;Fallopian secretory cells: 45.3;Gastric chief cells: 63.3;Mucous neck cells: 81.8;Müller glia: 51.9;Podocytes: 314.6;Salivary myoepithelial cells: 45.5;Schwann cells: 114.4;Smooth muscle cells: 111.0;Vascular smooth muscle cells: 93.9" "Group enriched" "Detected in many" 6 "astrocyte: 18.7;vascular associated smooth muscle cell: 47.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "white matter: 36.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 8.8" "Adipose subcutaneous - Smooth muscle cells, Minor Salivary Gland - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA029595 Approved Approved Vesicles "Secreted to extracellular matrix" "No annotated function" NA NA 7600 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 22: Non-specific - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 62: Smooth muscle cells - Muscle contraction" Vesicles "HPA029595: " "unprognostic (6.40e-3)" "potential prognostic favorable (7.47e-4)" "unprognostic (1.70e-2)" "unprognostic (1.27e-1)" "unprognostic (4.92e-2)" "unprognostic (3.74e-2)" "unprognostic (1.08e-1)" "unprognostic (9.45e-2)" "unprognostic (2.38e-2)" "unprognostic (6.74e-2)" "unprognostic (9.68e-2)" "unprognostic (1.06e-1)" "unprognostic (5.72e-2)" "unprognostic (3.52e-2)" "unprognostic (3.71e-1)" "unprognostic (2.36e-2)" "unprognostic (5.31e-2)" "unprognostic (1.69e-3)" "unprognostic (8.23e-2)" "unprognostic (1.27e-1)" "unprognostic (9.25e-2)" "unprognostic (1.50e-1)" "unprognostic (3.03e-1)" "unprognostic (1.10e-1)" "unprognostic (1.65e-1)" "unprognostic (5.44e-2)" SC5D SC5DL ENSG00000109929 Sterol-C5-desaturase O75845 11 121292681-121313410 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 367.9" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 177.6;Esophageal apical cells: 167.5;Hepatocytes: 179.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Minor Salivary Gland - Minor salivary gland basal cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066283, HPA070248" Enhanced Approved "Nucleoplasm,Endoplasmic reticulum,Plasma membrane,Cytosol" No No "Cluster 30: Non-specific - DNA binding" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 49: Hindbrain - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 2 "Nucleoplasm, Endoplasmic reticulum" "Plasma membrane, Cytosol" "HPA066283: , HPA070248: " "unprognostic (9.31e-2)" "unprognostic (4.47e-2)" "unprognostic (5.06e-2)" "unprognostic (1.71e-1)" "unprognostic (2.34e-2)" "unprognostic (1.39e-1)" "unprognostic (1.34e-2)" "potential prognostic unfavorable (1.42e-4)" "unprognostic (4.01e-3)" "potential prognostic favorable (3.54e-9)" "unprognostic (5.97e-3)" "unprognostic (1.23e-1)" "unprognostic (1.93e-2)" "unprognostic (7.27e-2)" "unprognostic (2.39e-1)" "unprognostic (1.07e-1)" "unprognostic (3.34e-1)" "unprognostic (1.77e-1)" "unprognostic (2.09e-2)" "unprognostic (4.07e-2)" "unprognostic (6.34e-2)" "unprognostic (1.43e-1)" "unprognostic (1.88e-1)" "unprognostic (1.46e-2)" "potential prognostic unfavorable (4.13e-5)" "unprognostic (7.53e-2)" "unprognostic (2.70e-1)" "unprognostic (2.65e-1)" "unprognostic (2.79e-1)" SCAF1 "FLJ00034, SR-A1" ENSG00000126461 "SR-related CTD associated factor 1" Q9H7N4 19 49642209-49658642 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 174.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046828, HPA054593" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 24: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 15 Nucleoplasm Cytosol "HPA046828: , HPA054593: " "unprognostic (3.95e-2)" "unprognostic (3.82e-2)" "unprognostic (2.32e-1)" "unprognostic (3.24e-3)" "unprognostic (1.76e-1)" "unprognostic (1.87e-2)" "unprognostic (1.11e-1)" "unprognostic (5.48e-2)" "unprognostic (2.70e-1)" "unprognostic (5.11e-2)" "unprognostic (1.70e-3)" "unprognostic (1.47e-1)" "unprognostic (2.10e-1)" "potential prognostic unfavorable (4.83e-5)" "unprognostic (8.09e-2)" "unprognostic (7.33e-3)" "unprognostic (9.86e-2)" "unprognostic (2.77e-1)" "unprognostic (3.69e-1)" "unprognostic (9.21e-3)" "unprognostic (4.25e-2)" "unprognostic (8.61e-2)" "unprognostic (9.36e-2)" "unprognostic (1.27e-2)" "unprognostic (1.87e-1)" "unprognostic (1.59e-1)" "unprognostic (1.70e-1)" "unprognostic (1.30e-1)" "unprognostic (1.65e-1)" "unprognostic (3.26e-2)" "unprognostic (1.39e-1)" SCAF11 "CASP11, SFRS2IP, SIP1, SRRP129, SRSF2IP" ENSG00000139218 "SR-related CTD associated factor 11" Q99590 12 45919131-45992120 "Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038862, HPA045456, HPA046345" Supported Enhanced "Nucleoplasm,Nucleoli,Nuclear bodies" NA NA "Cluster 32: Basophils - Transcription" "Cluster 40: Non-specific - Mixed function" "Cluster 55: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 22 Nucleoplasm "Nucleoli, Nuclear bodies" "HPA038862: , HPA045456: , HPA046345: " "unprognostic (1.58e-1)" "unprognostic (1.67e-2)" "unprognostic (4.57e-2)" "unprognostic (1.95e-1)" "unprognostic (1.18e-1)" "unprognostic (5.68e-2)" "unprognostic (3.31e-1)" "unprognostic (1.09e-1)" "potential prognostic unfavorable (1.40e-4)" "unprognostic (1.54e-3)" "unprognostic (3.98e-3)" "unprognostic (4.00e-2)" "unprognostic (4.14e-3)" "unprognostic (1.12e-1)" "unprognostic (1.57e-1)" "unprognostic (4.30e-2)" "unprognostic (1.16e-1)" "unprognostic (4.04e-1)" "unprognostic (3.05e-1)" "unprognostic (2.52e-2)" "unprognostic (7.60e-3)" "unprognostic (5.75e-3)" "unprognostic (1.87e-2)" "unprognostic (7.21e-3)" "unprognostic (4.62e-1)" "unprognostic (4.97e-2)" "unprognostic (3.22e-1)" "unprognostic (1.72e-1)" "unprognostic (3.54e-2)" "unprognostic (1.42e-1)" SCAF4 "DKFZp434E098, KIAA1172, SFRS15, SRA4" ENSG00000156304 "SR-related CTD associated factor 4" O95104 21 31671000-31732118 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" RNA-binding "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018319, HPA018668, HPA021504, HPA028807" Enhanced Enhanced Nucleoplasm NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 47: Leukemia - Hemostasis" "Cluster 17: Non-specific - RNA processing" 19 Nucleoplasm "HPA018319: , HPA018668: , HPA021504: , HPA028807: " "unprognostic (3.59e-2)" "unprognostic (1.26e-2)" "unprognostic (2.42e-3)" "unprognostic (5.75e-2)" "unprognostic (1.71e-1)" "unprognostic (1.95e-1)" "unprognostic (3.15e-1)" "unprognostic (1.03e-1)" "unprognostic (1.11e-1)" "unprognostic (3.19e-3)" "unprognostic (1.11e-2)" "unprognostic (1.02e-1)" "unprognostic (1.40e-2)" "unprognostic (5.04e-2)" "unprognostic (6.54e-3)" "unprognostic (5.45e-3)" "unprognostic (1.16e-1)" "unprognostic (3.61e-2)" "unprognostic (5.71e-2)" "unprognostic (8.86e-2)" "unprognostic (1.87e-1)" "unprognostic (5.87e-2)" "unprognostic (1.91e-3)" "unprognostic (7.77e-2)" "unprognostic (2.38e-1)" "unprognostic (4.88e-2)" "unprognostic (1.82e-1)" "unprognostic (9.94e-2)" "unprognostic (3.15e-1)" "unprognostic (1.22e-1)" SCAF8 "KIAA1116, RBM16" ENSG00000213079 "SR-related CTD associated factor 8" Q9UPN6 6 154733378-154834244 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035601, HPA035602" Enhanced Enhanced Nucleoplasm NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" 4 Nucleoplasm "HPA035601: , HPA035602: " "unprognostic (1.90e-3)" "potential prognostic unfavorable (2.34e-4)" "unprognostic (1.19e-2)" "unprognostic (2.39e-1)" "unprognostic (1.39e-1)" "unprognostic (1.76e-2)" "unprognostic (7.76e-2)" "unprognostic (7.78e-2)" "unprognostic (5.78e-2)" "potential prognostic favorable (9.69e-5)" "unprognostic (1.23e-2)" "unprognostic (7.76e-2)" "unprognostic (2.28e-3)" "unprognostic (3.87e-1)" "unprognostic (7.46e-2)" "unprognostic (2.76e-1)" "unprognostic (2.11e-1)" "unprognostic (4.43e-2)" "unprognostic (7.10e-3)" "unprognostic (1.78e-1)" "unprognostic (1.91e-1)" "unprognostic (3.48e-2)" "unprognostic (1.90e-1)" "unprognostic (7.09e-2)" "unprognostic (1.28e-2)" "unprognostic (2.00e-1)" "unprognostic (1.56e-1)" "unprognostic (1.70e-1)" "unprognostic (2.44e-1)" "unprognostic (3.82e-1)" SCAI "C9orf126, FLJ36664, NET40" ENSG00000173611 "Suppressor of cancer cell invasion" Q8N9R8 9 124942608-125143528 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Repressor, Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 10.4" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 256.7;Choroid plexus epithelial cells: 431.5;Retinal amacrine cells: 261.6;Retinal pigment epithelial cells: 498.8;Thymocytes: 271.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020632 Approved Supported "Nucleoplasm,Nuclear membrane" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 23: Choroid plexus - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 35: Neurons - Synaptic function & neurogenesis" 11 "Nucleoplasm, Nuclear membrane" "HPA020632: " "unprognostic (1.10e-1)" "unprognostic (2.09e-1)" "unprognostic (2.07e-1)" "unprognostic (8.42e-2)" "unprognostic (5.83e-2)" "unprognostic (9.25e-2)" "unprognostic (1.71e-1)" "unprognostic (2.09e-3)" "unprognostic (1.87e-3)" "unprognostic (6.45e-2)" "unprognostic (2.73e-3)" "potential prognostic favorable (2.99e-4)" "unprognostic (5.64e-2)" "unprognostic (5.83e-2)" "unprognostic (2.96e-3)" "unprognostic (2.61e-1)" "unprognostic (1.78e-1)" "potential prognostic favorable (1.22e-4)" "unprognostic (2.45e-1)" "unprognostic (7.60e-3)" "unprognostic (5.73e-2)" "unprognostic (2.53e-2)" "unprognostic (1.76e-1)" "potential prognostic favorable (3.50e-5)" "unprognostic (8.54e-2)" "unprognostic (4.83e-2)" "unprognostic (1.67e-1)" "unprognostic (1.26e-1)" "unprognostic (4.84e-2)" SCAMP1 SCAMP37 ENSG00000085365 "Secretory carrier membrane protein 1" O15126 5 78360611-78480739 "Essential proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044753, CAB079009" Supported Uncertain "Nucleoplasm,Vesicles,Cell Junctions" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 73: Brain - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 7: Non-specific - Transcription" 66 "Cell Junctions" "Nucleoplasm, Vesicles" "CAB079009: , HPA044753: " "unprognostic (3.19e-3)" "unprognostic (1.75e-1)" "unprognostic (3.66e-2)" "potential prognostic unfavorable (3.98e-4)" "unprognostic (1.31e-2)" "unprognostic (5.30e-2)" "unprognostic (2.59e-1)" "unprognostic (1.96e-2)" "unprognostic (7.68e-2)" "unprognostic (6.17e-2)" "potential prognostic favorable (3.41e-8)" "unprognostic (3.62e-2)" "unprognostic (2.50e-1)" "unprognostic (4.70e-2)" "unprognostic (1.57e-1)" "unprognostic (6.37e-3)" "unprognostic (5.80e-2)" "unprognostic (2.71e-1)" "unprognostic (2.31e-2)" "unprognostic (1.07e-2)" "unprognostic (4.65e-3)" "unprognostic (3.15e-2)" "unprognostic (8.96e-2)" "unprognostic (3.30e-1)" "unprognostic (6.73e-3)" "unprognostic (2.50e-1)" "unprognostic (1.87e-1)" "unprognostic (6.62e-2)" "unprognostic (2.87e-1)" "unprognostic (9.49e-3)" "unprognostic (1.79e-1)" SCAMP2 ENSG00000140497 "Secretory carrier membrane protein 2" O15127 15 74843730-74873365 "Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 394.7;Hofbauer cells: 225.3" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 122.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Adrenal cortex cells, Colon - Macrophages, Heart muscle - Macrophages, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014699, HPA019194" Approved Supported "Golgi apparatus,Vesicles,Mid piece,Principal piece" NA NA 230000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 17: Intestine - Digestion" "Cluster 8: Immune cells - Immune response" "Cluster 58: Non-specific - Nuclear processes" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 69 "Golgi apparatus, Vesicles" "Mid piece, Principal piece" "HPA014699: , HPA019194: " "unprognostic (1.91e-1)" "unprognostic (4.88e-2)" "unprognostic (5.50e-2)" "unprognostic (1.12e-1)" "unprognostic (3.32e-1)" "unprognostic (1.93e-1)" "unprognostic (2.98e-1)" "unprognostic (5.82e-2)" "unprognostic (1.09e-1)" "unprognostic (5.29e-2)" "potential prognostic favorable (4.51e-7)" "unprognostic (1.34e-2)" "unprognostic (2.07e-1)" "unprognostic (3.17e-2)" "potential prognostic unfavorable (4.44e-4)" "unprognostic (2.59e-1)" "unprognostic (5.90e-2)" "unprognostic (2.74e-1)" "unprognostic (9.06e-2)" "unprognostic (2.01e-1)" "unprognostic (2.19e-1)" "unprognostic (2.08e-1)" "unprognostic (5.55e-2)" "unprognostic (3.48e-1)" "unprognostic (9.34e-2)" "unprognostic (1.09e-1)" "unprognostic (6.56e-2)" "unprognostic (3.76e-1)" "unprognostic (1.69e-1)" "unprognostic (9.45e-2)" "unprognostic (7.65e-2)" SCAMP3 C1orf3 ENSG00000116521 "Secretory carrier membrane protein 3" O14828 1 155255979-155262430 "Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 20.3;Bergmann glia: 23.4;Brain excitatory neurons: 16.2;Brain inhibitory neurons: 15.5;Distal convoluted tubule cells: 15.7;Loop of henle epithelial cells: 16.3;Microglia: 20.9;Oligodendrocyte progenitor cells: 21.0;Oligodendrocytes: 27.7;Other brain neurons: 17.2;Podocytes: 18.1;Proximal tubule cells: 15.3;Renal collecting duct principal cells: 18.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071167 Supported Vesicles NA NA 25000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 98: Neurons - Neurotransmission & signaling" 15 Vesicles "HPA071167: " "unprognostic (6.66e-3)" "unprognostic (4.13e-2)" "unprognostic (3.82e-1)" "unprognostic (2.50e-2)" "unprognostic (2.75e-2)" "unprognostic (5.79e-3)" "unprognostic (5.79e-2)" "unprognostic (1.95e-3)" "unprognostic (7.11e-2)" "unprognostic (3.18e-1)" "unprognostic (3.30e-3)" "unprognostic (4.56e-2)" "unprognostic (5.12e-3)" "unprognostic (3.70e-3)" "unprognostic (1.32e-3)" "unprognostic (5.15e-2)" "unprognostic (1.99e-1)" "unprognostic (2.17e-2)" "unprognostic (9.65e-2)" "unprognostic (3.13e-2)" "unprognostic (2.53e-2)" "unprognostic (4.30e-2)" "unprognostic (5.30e-2)" "unprognostic (4.99e-2)" "unprognostic (7.92e-2)" "unprognostic (1.58e-2)" "unprognostic (9.34e-2)" "unprognostic (2.30e-1)" "unprognostic (2.95e-1)" "unprognostic (7.32e-3)" "unprognostic (4.43e-1)" SCAMP4 FLJ33847 ENSG00000227500 "Secretory carrier membrane protein 4" Q969E2 19 1905214-1926013 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fallopian tube ciliated cells: 85.9;Respiratory ciliated cells: 96.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043284 Approved Approved "Golgi apparatus,Vesicles,Lipid droplets,Plasma membrane" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 107: Ciliated cells - Cilia assembly & function" 18 "Golgi apparatus, Vesicles" "Lipid droplets, Plasma membrane" "HPA043284: " "unprognostic (1.23e-1)" "unprognostic (6.99e-2)" "unprognostic (2.72e-1)" "unprognostic (8.56e-2)" "unprognostic (1.51e-1)" "unprognostic (1.78e-1)" "unprognostic (2.21e-1)" "unprognostic (4.99e-2)" "unprognostic (1.48e-1)" "unprognostic (1.09e-1)" "unprognostic (5.19e-2)" "unprognostic (1.82e-2)" "unprognostic (6.45e-2)" "potential prognostic unfavorable (3.47e-7)" "unprognostic (2.89e-2)" "unprognostic (3.37e-2)" "unprognostic (4.69e-2)" "unprognostic (1.02e-1)" "unprognostic (1.20e-1)" "unprognostic (1.26e-1)" "unprognostic (1.50e-1)" "unprognostic (1.03e-3)" "unprognostic (1.67e-1)" "unprognostic (1.84e-1)" "unprognostic (3.43e-2)" "unprognostic (1.12e-2)" "unprognostic (2.00e-1)" "unprognostic (2.41e-2)" "unprognostic (2.37e-2)" "unprognostic (3.19e-2)" "potential prognostic favorable (1.00e-4)" SCAMP5 MGC24969 ENSG00000198794 "Secretory carrier membrane protein 5" Q8TAC9 15 74957219-75021495 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 200.0;retina: 263.3" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 107.4;Brain inhibitory neurons: 134.7;Cone photoreceptor cells: 219.4;Gonadotrophs: 118.1;Neuroendocrine cells: 111.5;pDCs: 160.6;Retinal amacrine cells: 124.2;Retinal bipolar cells: 158.2;Rod photoreceptor cells: 513.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 37 "plasmacytoid DC: 27.7" "Lineage enriched" "Detected in single" 37 "dendritic cells: 27.7" "Cancer enhanced" "Detected in many" "Neuroblastoma: 76.5" "Colon - Colon enteroendocrine cells, Pituitary gland - Lactotropes, Spleen - Plasma cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046645 Enhanced NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 79: Photoreceptor cells - Phototransduction" 15 "HPA046645: " "potential prognostic favorable (6.52e-4)" "unprognostic (1.18e-1)" "unprognostic (5.70e-2)" "unprognostic (5.61e-2)" "unprognostic (3.58e-1)" "unprognostic (3.07e-1)" "unprognostic (2.61e-1)" "potential prognostic favorable (6.82e-4)" "unprognostic (5.65e-2)" "unprognostic (1.93e-1)" "unprognostic (1.35e-3)" "unprognostic (9.39e-3)" "potential prognostic favorable (9.28e-5)" "unprognostic (3.24e-1)" "unprognostic (6.15e-2)" "unprognostic (8.81e-2)" "unprognostic (3.68e-1)" "unprognostic (7.19e-2)" "unprognostic (1.73e-1)" "unprognostic (7.75e-2)" "unprognostic (2.81e-1)" "potential prognostic favorable (2.97e-5)" "unprognostic (3.36e-2)" "unprognostic (1.66e-1)" "unprognostic (2.79e-1)" "unprognostic (4.10e-2)" "unprognostic (4.43e-1)" "unprognostic (1.75e-1)" "unprognostic (2.82e-1)" "unprognostic (7.43e-2)" "unprognostic (6.84e-2)" SCAND1 "RAZ1, SDP1" ENSG00000171222 "SCAN domain containing 1" P57086 20 35953617-35959472 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 449.2;Esophageal apical cells: 517.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA071335 Approved "Nuclear speckles" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 80 "Nuclear speckles" "HPA071335: " "unprognostic (1.01e-1)" "unprognostic (6.82e-2)" "unprognostic (3.08e-1)" "unprognostic (2.00e-1)" "unprognostic (5.00e-2)" "unprognostic (2.71e-1)" "unprognostic (3.93e-1)" "unprognostic (3.06e-1)" "unprognostic (4.40e-2)" "unprognostic (1.28e-3)" "unprognostic (2.35e-2)" "unprognostic (2.71e-1)" "unprognostic (5.55e-2)" "unprognostic (1.12e-1)" "unprognostic (5.90e-2)" "unprognostic (1.62e-1)" "unprognostic (3.05e-1)" "unprognostic (1.98e-1)" "unprognostic (1.95e-1)" "unprognostic (1.01e-1)" "unprognostic (2.16e-2)" "potential prognostic favorable (9.32e-4)" "unprognostic (2.47e-1)" "unprognostic (6.55e-2)" "unprognostic (7.61e-2)" "unprognostic (1.56e-3)" "unprognostic (9.74e-2)" "unprognostic (9.20e-2)" "unprognostic (2.35e-1)" "unprognostic (7.46e-2)" "unprognostic (1.33e-1)" SCAP KIAA0199 ENSG00000114650 "SREBF chaperone" Q12770 3 47413681-47477126 "Predicted membrane proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 189.3;Sertoli cells: 210.9;Syncytiotrophoblasts: 320.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004713 Approved NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 76: Non-specific - Metabolism" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 37 "HPA004713: " "unprognostic (4.20e-2)" "unprognostic (2.78e-1)" "unprognostic (3.95e-2)" "unprognostic (3.72e-1)" "unprognostic (1.39e-1)" "unprognostic (3.36e-1)" "unprognostic (1.28e-1)" "unprognostic (1.03e-2)" "unprognostic (1.47e-1)" "unprognostic (1.00e-2)" "unprognostic (2.68e-1)" "unprognostic (6.25e-2)" "unprognostic (2.79e-2)" "unprognostic (1.12e-1)" "unprognostic (1.42e-1)" "unprognostic (3.85e-2)" "unprognostic (1.14e-1)" "unprognostic (3.08e-1)" "unprognostic (1.08e-1)" "unprognostic (7.96e-2)" "unprognostic (2.23e-1)" "unprognostic (1.75e-3)" "unprognostic (2.12e-1)" "unprognostic (1.31e-1)" "unprognostic (8.85e-2)" "unprognostic (2.84e-1)" "unprognostic (2.89e-2)" "unprognostic (2.43e-1)" "unprognostic (5.27e-1)" "unprognostic (1.72e-2)" "unprognostic (5.55e-3)" SCAPER "Zfp291, ZNF291" ENSG00000140386 "S-phase cyclin A associated protein in the ER" Q9BY12 15 76347904-76905444 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Intellectual disability, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 51.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 859.1;Rod photoreceptor cells: 2165.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046253, HPA048077" Approved Supported "Nucleoplasm,Nuclear speckles,Primary cilium,Primary cilium tip,Basal body,Cytosol" NA No "Cluster 22: Eosinophils - Transcription" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 31: Non-specific - Transcription" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 79: Photoreceptor cells - Phototransduction" 5 "Nucleoplasm, Nuclear speckles" "Primary cilium, Primary cilium tip, Basal body, Cytosol" "HPA046253: , HPA048077: " "unprognostic (6.75e-3)" "unprognostic (8.70e-2)" "unprognostic (1.70e-2)" "unprognostic (1.45e-1)" "unprognostic (2.94e-1)" "unprognostic (1.02e-1)" "unprognostic (3.68e-2)" "unprognostic (4.33e-2)" "unprognostic (3.42e-1)" "unprognostic (1.36e-2)" "validated prognostic favorable (1.08e-9)" "validated prognostic favorable (3.58e-4)" "unprognostic (8.54e-2)" "unprognostic (5.37e-2)" "unprognostic (2.26e-1)" "unprognostic (2.17e-2)" "unprognostic (2.15e-2)" "unprognostic (8.62e-2)" "unprognostic (2.44e-1)" "unprognostic (1.56e-1)" "unprognostic (5.27e-2)" "unprognostic (2.18e-1)" "unprognostic (3.81e-2)" "unprognostic (2.20e-1)" "unprognostic (1.25e-2)" "potential prognostic favorable (3.51e-4)" "unprognostic (1.72e-1)" "unprognostic (2.37e-1)" "unprognostic (4.20e-1)" "unprognostic (3.13e-1)" "unprognostic (2.01e-1)" SCARA3 "APC7, CSR, CSR1, MSLR1, MSRL1" ENSG00000168077 "Scavenger receptor class A member 3" Q6AZY7 8 27633868-27676776 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 114.3;Bergmann glia: 123.1;Cytotrophoblasts: 70.1;Endometrial secretory cells: 73.6;Epididymal basal cells: 65.3;Fallopian secretory cells: 168.0;Hepatic stellate cells: 77.5;Medullary thymic epithelial cells: 136.8;Migrating cytotrophoblasts: 66.1;Müller glia: 65.9;Ocular epithelial cells: 81.5;Smooth muscle cells: 64.0;Submucosal glandular cells: 94.0" "Cell type enhanced" "Detected in many" "astrocyte: 163.0;Bergmann glia: 117.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Lung - Fibroblasts_2, Prostate - Smooth muscle cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029861, HPA047386" Uncertain Supported "Endoplasmic reticulum" NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 44: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 5 "Endoplasmic reticulum" "HPA029861: , HPA047386: " "unprognostic (3.32e-1)" "unprognostic (9.39e-2)" "unprognostic (7.33e-2)" "unprognostic (2.11e-1)" "unprognostic (2.92e-2)" "unprognostic (2.13e-1)" "unprognostic (6.89e-3)" "unprognostic (4.11e-1)" "unprognostic (3.08e-1)" "unprognostic (4.76e-3)" "unprognostic (1.06e-1)" "unprognostic (8.45e-2)" "unprognostic (3.39e-2)" "unprognostic (3.05e-1)" "unprognostic (1.55e-1)" "unprognostic (1.31e-1)" "unprognostic (2.76e-1)" "unprognostic (5.33e-2)" "unprognostic (3.38e-1)" "unprognostic (2.82e-1)" "unprognostic (1.13e-1)" "unprognostic (3.36e-1)" "unprognostic (1.91e-1)" "unprognostic (1.29e-1)" "unprognostic (3.64e-2)" "unprognostic (2.67e-2)" "unprognostic (1.08e-2)" "unprognostic (6.20e-2)" "unprognostic (2.57e-1)" "unprognostic (1.49e-2)" "unprognostic (1.47e-2)" SCARA5 "FLJ23907, MGC45780, NET33" ENSG00000168079 "Scavenger receptor class A member 5" Q6ZMJ2 8 27869883-27992673 "Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Iron transport, Transport" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 87.1;urinary bladder: 82.3" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 53.2;Decidual stromal cells: 145.7;Endometrial stromal cells: 38.4;Fibro-adipogenic progenitors: 263.8;Fibroblasts: 293.3;Leydig cells: 200.5;Myosatellite cells: 91.6" "Group enriched" "Detected in some" 6 "fibroblast: 57.4;MGE interneuron: 24.1" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 6.0" "Region enriched" "Detected in many" 5 "choroid plexus: 10.4" "Immune cell enriched" "Detected in single" 121 "plasmacytoid DC: 21.1" "Lineage enriched" "Detected in single" 212 "dendritic cells: 21.1" "Group enriched" "Detected in some" 4 "Rhabdoid: 12.3;Sarcoma: 17.0" "Breast - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblasts_2, Minor Salivary Gland - Fibroblasts, Pancreas - Fibroblasts, Skin - Fibroblasts_2" "Low region specificity" "Detected in single" "Region enriched" "Detected in many" 5 "spinal cord: 25.7" HPA024661 Approved NA NA 540000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" "HPA024661: " "unprognostic (8.40e-3)" "unprognostic (3.26e-2)" "unprognostic (2.64e-3)" "unprognostic (1.55e-3)" "unprognostic (5.33e-2)" "unprognostic (1.92e-3)" "unprognostic (1.11e-1)" "unprognostic (1.03e-1)" "unprognostic (3.58e-2)" "unprognostic (1.48e-2)" "unprognostic (1.76e-1)" "unprognostic (8.24e-2)" "unprognostic (3.50e-1)" "unprognostic (1.75e-1)" "unprognostic (2.33e-1)" "unprognostic (5.85e-2)" "unprognostic (2.26e-2)" "unprognostic (1.74e-1)" "unprognostic (4.99e-2)" SCARB1 "CD36L1, CLA-1, CLA1, SR-BI, SRB1" ENSG00000073060 "Scavenger receptor class B member 1" Q8WTV0 12 124776856-124882668 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "adrenal gland: 235.6;liver: 66.0;placenta: 104.6" "Cell type enriched" "Detected in many" 10 "Adrenal cortex cells: 2251.3" "Cell type enhanced" "Detected in all" "endothelial cell: 259.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 22.0" "Group enriched" "Detected in many" 6 "dendritic cells: 22.0;monocytes: 6.4" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Endothelial cells, Pituitary gland - Undifferentiated cells (Pituitary gland)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066285, CAB070124, HPA072449" Enhanced Approved "Vesicles,Lysosomes,Rods & Rings" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 12: Non-specific - Vasculature" "Cluster 7: Liver cancer - Metabolism" "Cluster 18: Adrenal cortex cells - Steroidogensis" 13 Vesicles "Lysosomes, Rods & Rings" "CAB070124: , HPA066285: , HPA072449: " "unprognostic (1.15e-1)" "unprognostic (2.68e-1)" "unprognostic (1.47e-1)" "unprognostic (2.30e-2)" "unprognostic (4.48e-2)" "unprognostic (1.67e-1)" "unprognostic (7.16e-2)" "unprognostic (8.68e-2)" "unprognostic (1.31e-2)" "unprognostic (1.25e-2)" "potential prognostic favorable (2.95e-5)" "unprognostic (4.19e-3)" "unprognostic (2.14e-1)" "unprognostic (8.24e-2)" "unprognostic (4.83e-2)" "unprognostic (3.10e-3)" "unprognostic (2.66e-1)" "unprognostic (4.04e-3)" "unprognostic (6.38e-2)" "unprognostic (1.61e-1)" "unprognostic (4.85e-2)" "unprognostic (1.55e-1)" "unprognostic (3.16e-2)" "unprognostic (1.82e-1)" "unprognostic (9.46e-3)" "unprognostic (1.68e-1)" "unprognostic (4.35e-1)" "unprognostic (9.99e-2)" "unprognostic (2.21e-1)" "unprognostic (2.36e-2)" "unprognostic (7.08e-2)" SCARB2 "CD36L2, HLGP85, LIMP-2, LIMPII, SR-BII" ENSG00000138760 "Scavenger receptor class B member 2" Q14108 4 76158737-76234536 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Kupffer cells: 426.4;Prostatic glandular cells: 501.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 11.7;classical monocyte: 14.1;intermediate monocyte: 26.0;myeloid DC: 8.1;non-classical monocyte: 25.0;plasmacytoid DC: 28.8" "Group enriched" "Detected in all" 5 "dendritic cells: 28.8;granulocytes: 11.7;monocytes: 26.0" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015415, HPA018014" Supported Approved Cytosol NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 28: Liver & Adrenal gland - Secretion" "Cluster 30: White matter - Myelination" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 13 Cytosol "CAB015415: , HPA018014: " "unprognostic (8.32e-3)" "unprognostic (3.71e-3)" "unprognostic (2.50e-1)" "potential prognostic unfavorable (8.25e-4)" "unprognostic (1.76e-2)" "unprognostic (3.54e-1)" "unprognostic (3.64e-1)" "unprognostic (3.23e-2)" "unprognostic (4.43e-2)" "unprognostic (1.73e-3)" "potential prognostic favorable (5.86e-7)" "unprognostic (1.69e-2)" "unprognostic (1.59e-1)" "unprognostic (1.17e-1)" "unprognostic (2.10e-2)" "unprognostic (1.28e-2)" "potential prognostic unfavorable (6.24e-4)" "unprognostic (1.85e-2)" "unprognostic (3.72e-1)" "unprognostic (1.39e-3)" "unprognostic (1.68e-1)" "unprognostic (1.72e-2)" "unprognostic (1.81e-1)" "unprognostic (2.44e-1)" "unprognostic (3.07e-2)" "unprognostic (4.37e-2)" "unprognostic (6.18e-2)" "unprognostic (1.89e-1)" "unprognostic (1.31e-1)" "unprognostic (3.90e-2)" "unprognostic (1.56e-1)" SCARF1 "KIAA0149, SREC, SREC1" ENSG00000074660 "Scavenger receptor class F member 1" Q14162 17 1633858-1645744 "Predicted membrane proteins" "Cell adhesion" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 25.8" "Cell type enhanced" "Detected in some" "Astrocytes: 7.0;Choroid plexus epithelial cells: 25.6;Distal convoluted tubule cells: 10.2;Ependymal cells: 4.7;Loop of henle epithelial cells: 9.8;Microglia: 19.5;Papillary tip epithelial cells: 7.7;Proximal tubule cells: 6.4;Renal collecting duct intercalated cells: 20.0;Renal collecting duct principal cells: 5.7;Renal connecting tubule cells: 14.2" "Cell type enhanced" "Detected in many" "endothelial cell: 60.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "neutrophil: 3.1" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Minor Salivary Gland - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA035108, HPA072936" Enhanced Approved "Golgi apparatus" NA NA 790000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 5: Spleen - Immune response" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 104: Brain endothelial cells - Blood brain barrier" 18 "Golgi apparatus" "HPA035108: , HPA072936: " "unprognostic (1.93e-1)" "unprognostic (2.88e-1)" "unprognostic (2.35e-2)" "unprognostic (1.09e-1)" "unprognostic (3.37e-1)" "unprognostic (1.16e-1)" "unprognostic (3.31e-1)" "unprognostic (1.04e-1)" "unprognostic (7.41e-2)" "unprognostic (1.87e-3)" "unprognostic (1.60e-2)" "unprognostic (2.65e-1)" "unprognostic (7.58e-2)" "potential prognostic favorable (8.23e-5)" "unprognostic (2.34e-3)" "unprognostic (1.63e-2)" "unprognostic (2.29e-3)" "unprognostic (3.16e-1)" "unprognostic (6.53e-2)" "unprognostic (8.43e-2)" "unprognostic (3.64e-3)" "unprognostic (1.58e-3)" "unprognostic (1.94e-1)" "unprognostic (2.95e-1)" "unprognostic (2.07e-2)" "unprognostic (3.28e-2)" SCARF2 "HUMZD58C02, SREC-II, SREC2" ENSG00000244486 "Scavenger receptor class F member 2" Q96GP6 22 20424584-20437826 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Cell adhesion" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 47.5" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 19.7;Fallopian tube ciliated cells: 28.6;Fibroblasts: 29.9;Hepatic stellate cells: 19.4;Leydig cells: 30.7;Pericytes: 23.7;Peritubular myoid cells: 30.5;Respiratory ciliated cells: 58.6;Vascular smooth muscle cells: 21.8" "Cell type enhanced" "Detected in many" "fibroblast: 39.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Heart muscle - Fibroblasts, Prostate - Fibroblasts, Skin - Fibroblasts_2, Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA035079 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 2900000 "Cluster 74: Non-specific - Signal transduction" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 108: Fibroblasts - ECM organization" 2 Nucleoplasm "Nuclear bodies, Cytosol" "HPA035079: " "unprognostic (2.58e-2)" "unprognostic (1.68e-1)" "unprognostic (3.98e-2)" "unprognostic (1.84e-2)" "unprognostic (5.03e-3)" "unprognostic (6.40e-2)" "unprognostic (4.03e-1)" "unprognostic (1.82e-1)" "unprognostic (3.16e-1)" "unprognostic (5.38e-3)" "unprognostic (4.92e-2)" "unprognostic (1.52e-1)" "unprognostic (4.10e-2)" "unprognostic (7.71e-2)" "unprognostic (1.22e-2)" "unprognostic (1.05e-1)" "unprognostic (2.14e-1)" "unprognostic (1.04e-2)" "unprognostic (1.53e-1)" "unprognostic (4.83e-2)" "unprognostic (7.69e-2)" "unprognostic (2.44e-1)" "unprognostic (3.44e-1)" "unprognostic (1.55e-1)" "unprognostic (6.32e-2)" "unprognostic (4.11e-3)" "unprognostic (4.29e-2)" "unprognostic (5.01e-3)" "unprognostic (6.29e-2)" "potential prognostic unfavorable (9.11e-4)" "unprognostic (1.55e-1)" SCART1 CD163c-alpha ENSG00000214279 "Scavenger receptor family member expressed on T cells 1" Q4G0T1 10 133453928-133523558 "Predicted membrane proteins" Immunity "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in single" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 34.9;Esophageal apical cells: 36.6;Innate lymphoid cells: 105.5;Rod photoreceptor cells: 37.1" "Cell type enriched" "Detected in all" 4 "hippocampal dentate gyrus: 161.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" HPA043101 Supported NA NA "Cluster 40: Non-specific - Mixed function" "Cluster 29: Forebrain - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 35: Neurons - Synaptic function & neurogenesis" "HPA043101: " "potential prognostic favorable (2.87e-5)" "unprognostic (2.57e-1)" "unprognostic (2.06e-3)" SCCPDH "CGI-49, NET11" ENSG00000143653 "Saccharopine dehydrogenase (putative)" Q8NBX0 1 246724409-246768137 "Metabolic proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 1240.6;Late primary spermatocytes: 2111.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 20 "basophil: 875.3" "Lineage enriched" "Detected in all" 26 "granulocytes: 875.3" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Spleen - Macrophages, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050775, HPA076030" Enhanced Approved Vesicles NA NA 29000 "Cluster 41: Basophils - Unknown function" "Cluster 67: Testis - Mixed function" "Cluster 30: White matter - Myelination" "Cluster 45: Non-specific - Nuclear processes" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 5 Vesicles "HPA050775: , HPA076030: " "unprognostic (1.93e-1)" "unprognostic (2.42e-1)" "unprognostic (2.99e-1)" "unprognostic (1.48e-1)" "unprognostic (2.06e-2)" "unprognostic (3.73e-1)" "unprognostic (9.53e-2)" "unprognostic (9.58e-2)" "unprognostic (4.88e-2)" "unprognostic (8.87e-2)" "potential prognostic favorable (8.82e-4)" "unprognostic (1.39e-2)" "unprognostic (1.32e-1)" "unprognostic (3.56e-1)" "unprognostic (1.89e-1)" "unprognostic (5.80e-2)" "unprognostic (8.04e-2)" "unprognostic (1.68e-1)" "unprognostic (4.61e-2)" "unprognostic (1.27e-1)" "unprognostic (1.98e-1)" "unprognostic (2.26e-1)" "unprognostic (1.75e-1)" "unprognostic (7.42e-2)" "unprognostic (4.29e-2)" "unprognostic (3.78e-2)" "unprognostic (3.03e-1)" "unprognostic (1.75e-2)" "unprognostic (6.90e-2)" "unprognostic (5.31e-2)" "unprognostic (3.13e-1)" SCD "FADS5, SCD1, SCDOS" ENSG00000099194 "Stearoyl-CoA desaturase" O00767 10 100347233-100364826 "Enzymes, Essential proteins, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 1158.4;brain: 979.4;liver: 546.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 631.7;Esophageal apical cells: 705.3;Esophageal suprabasal cells: 429.7;Hepatocytes: 250.3;Kupffer cells: 211.1;Oligodendrocytes: 541.0;Respiratory ionocytes: 188.0;Transitional alveolar cells: 201.4" "Group enriched" "Detected in all" 5 "committed oligodendrocyte precursor: 205.0;oligodendrocyte: 714.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Spleen - Macrophages, Testis - Sertoli cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA012107, HPA063921" Approved Enhanced "Endoplasmic reticulum" No Yes 27000 "Cluster 30: Non-specific - DNA binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 53 "Endoplasmic reticulum" "HPA012107: , HPA063921: " "potential prognostic unfavorable (9.23e-4)" "unprognostic (1.14e-1)" "unprognostic (2.12e-1)" "unprognostic (2.38e-3)" "unprognostic (3.43e-2)" "unprognostic (4.36e-2)" "unprognostic (1.65e-1)" "unprognostic (4.61e-1)" "unprognostic (4.15e-2)" "unprognostic (1.80e-3)" "unprognostic (2.07e-1)" "unprognostic (5.24e-2)" "unprognostic (3.02e-2)" "unprognostic (5.93e-2)" "unprognostic (1.25e-2)" "unprognostic (6.16e-3)" "unprognostic (1.14e-1)" "unprognostic (3.25e-1)" "unprognostic (1.03e-1)" "unprognostic (2.93e-1)" "unprognostic (4.87e-1)" "unprognostic (8.85e-2)" "unprognostic (9.55e-2)" "unprognostic (8.12e-2)" "unprognostic (8.88e-2)" "unprognostic (3.19e-2)" "unprognostic (4.18e-2)" "unprognostic (6.96e-2)" "unprognostic (2.25e-1)" "unprognostic (8.36e-2)" "unprognostic (8.74e-3)" SCD5 "ACOD4, FADS4, FLJ21032, HSCD5, SCD4" ENSG00000145284 "Stearoyl-CoA desaturase 5" Q86SK9 4 82629539-82798796 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 147.8;brain: 293.9" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 511.1;Astrocytes: 403.2;Bergmann glia: 1083.1;Epididymal efferent duct absorptive cells: 428.1;Oligodendrocyte progenitor cells: 1526.6;Oligodendrocytes: 940.1;Pituitary stem cells: 632.3" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 1348.7;oligodendrocyte precursor cell: 1725.2" "Cancer enriched" "Detected in all" 4 "Glioblastoma Multiforme (TCGA): 339.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Colon - Colon enteroendocrine cells, Lung - Alveolar cells type 1, Prostate - Fibroblasts, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" HPA042380 Uncertain NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 36: Brain & Liver - Signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 2 "HPA042380: " "unprognostic (4.38e-2)" "unprognostic (8.66e-2)" "unprognostic (1.09e-1)" "unprognostic (2.67e-2)" "unprognostic (1.96e-1)" "unprognostic (1.56e-1)" "unprognostic (6.34e-2)" "unprognostic (9.55e-2)" "unprognostic (4.81e-1)" "unprognostic (3.57e-2)" "potential prognostic favorable (2.16e-6)" "unprognostic (7.95e-3)" "unprognostic (9.93e-3)" "unprognostic (4.21e-2)" "unprognostic (1.84e-1)" "unprognostic (4.69e-2)" "unprognostic (6.41e-2)" "unprognostic (1.90e-2)" "unprognostic (5.18e-3)" "unprognostic (1.62e-1)" "unprognostic (1.33e-1)" "unprognostic (5.01e-2)" "unprognostic (1.82e-2)" "unprognostic (8.86e-2)" "unprognostic (2.55e-1)" "unprognostic (6.24e-2)" "unprognostic (3.35e-2)" "unprognostic (2.63e-2)" "unprognostic (7.77e-2)" "unprognostic (2.23e-2)" "unprognostic (2.24e-1)" SCEL "FLJ21667, MGC22531" ENSG00000136155 Sciellin O95171 13 77535674-77645263 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 350.3;skin 1: 285.8" "Cell type enriched" "Detected in many" 8 "Esophageal apical cells: 7219.7" "Cell type enhanced" "Detected in some" "Bergmann glia: 3.3;cerebellar inhibitory: 4.4;oligodendrocyte: 4.9" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 34.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 54.0;pancreatic cancer: 51.0" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 1" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA039737, HPA040154" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" No No 6000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 6 "Plasma membrane" "Nucleoplasm, Cytosol" "HPA039737: , HPA040154: " "unprognostic (1.53e-1)" "unprognostic (9.94e-2)" "unprognostic (3.01e-2)" "unprognostic (2.33e-2)" "unprognostic (1.12e-1)" "potential prognostic favorable (6.10e-4)" "unprognostic (8.53e-2)" "unprognostic (5.68e-2)" "unprognostic (3.85e-2)" "unprognostic (1.12e-1)" "unprognostic (4.71e-2)" "unprognostic (2.20e-1)" "validated prognostic unfavorable (1.22e-4)" "validated prognostic unfavorable (5.97e-4)" "unprognostic (9.40e-2)" "unprognostic (1.07e-1)" "unprognostic (1.59e-1)" "unprognostic (3.42e-1)" "unprognostic (1.00e-2)" "unprognostic (1.38e-2)" SCFD1 "C14orf163, KIAA0917, RA410, SLY1, STXBP1L2" ENSG00000092108 "Sec1 family domain containing 1" Q8WVM8 14 30622291-30737694 "Essential proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003579 Approved NA NA 69000 "Cluster 13: Non-specific - Mitochondria" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 109 "HPA003579: " "unprognostic (4.42e-3)" "unprognostic (4.06e-2)" "unprognostic (1.47e-2)" "unprognostic (1.26e-1)" "unprognostic (4.12e-2)" "unprognostic (1.01e-1)" "unprognostic (1.56e-1)" "unprognostic (4.18e-3)" "unprognostic (3.08e-1)" "unprognostic (4.06e-2)" "potential prognostic favorable (2.40e-7)" "unprognostic (1.56e-1)" "unprognostic (7.82e-2)" "unprognostic (4.18e-3)" "unprognostic (8.82e-3)" "unprognostic (2.53e-2)" "unprognostic (1.82e-2)" "unprognostic (1.43e-1)" "unprognostic (2.62e-1)" "unprognostic (1.50e-1)" "unprognostic (5.52e-2)" "unprognostic (9.11e-3)" "potential prognostic unfavorable (2.89e-4)" "unprognostic (1.06e-1)" "unprognostic (2.56e-1)" "potential prognostic unfavorable (2.66e-4)" "unprognostic (2.03e-1)" "unprognostic (1.58e-1)" "unprognostic (2.21e-1)" "unprognostic (5.84e-2)" "unprognostic (8.00e-2)" SCFD2 "FLJ39514, STXBP1L1" ENSG00000184178 "Sec1 family domain containing 2" Q8WU76 4 52872982-53366066 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036526, HPA036527" Enhanced Approved Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 7: Non-specific - Transcription" 7 Nucleoplasm "HPA036526: , HPA036527: " "unprognostic (9.15e-2)" "unprognostic (2.16e-2)" "unprognostic (4.18e-2)" "unprognostic (3.32e-3)" "unprognostic (2.11e-2)" "unprognostic (2.00e-1)" "unprognostic (8.20e-2)" "unprognostic (1.04e-3)" "unprognostic (9.66e-2)" "unprognostic (2.52e-2)" "potential prognostic favorable (1.61e-9)" "unprognostic (5.01e-3)" "unprognostic (5.88e-2)" "unprognostic (1.10e-2)" "unprognostic (2.13e-2)" "unprognostic (9.85e-2)" "potential prognostic unfavorable (3.19e-5)" "unprognostic (2.33e-1)" "unprognostic (4.01e-2)" "unprognostic (1.01e-1)" "unprognostic (1.48e-2)" "unprognostic (7.76e-2)" "unprognostic (1.67e-1)" "unprognostic (8.62e-2)" "unprognostic (7.28e-3)" "unprognostic (5.07e-2)" "unprognostic (4.67e-3)" "unprognostic (1.72e-1)" "unprognostic (1.39e-1)" "unprognostic (5.37e-3)" "unprognostic (5.48e-2)" SCG2 "CHGC, SgII, SN" ENSG00000171951 "Secretogranin II" P13521 2 223596940-223602361 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "adrenal gland: 340.0;brain: 391.8;pituitary gland: 267.0" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 691.4;Brain inhibitory neurons: 181.4;Corticotrophs: 1184.6;Gonadotrophs: 341.0;Neuroendocrine cells: 280.8;Other brain neurons: 346.4;Pancreatic islet cells: 2077.8;Retinal amacrine cells: 166.7" "Cell type enhanced" "Detected in all" "CGE interneuron: 475.9" "Group enriched" "Detected in many" 7 "Glioblastoma Multiforme (TCGA): 110.0;Pancreatic Adenocarcinoma (TCGA): 84.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 319.4;Rhabdoid: 457.9" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Thyroid gland - Parafollicular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011893, HPA075062" Enhanced Supported Approved "Golgi apparatus,Vesicles" "Secreted to blood" "No annotated function" NA NA 300000 "Cluster 36: Brain & Liver - Signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 3 "Golgi apparatus" Vesicles "HPA011893: , HPA075062: " "unprognostic (4.35e-1)" "unprognostic (1.96e-2)" "unprognostic (1.57e-1)" "unprognostic (1.32e-2)" "unprognostic (2.64e-2)" "unprognostic (1.09e-2)" "unprognostic (6.77e-2)" "unprognostic (1.70e-2)" "unprognostic (2.18e-1)" "unprognostic (1.57e-3)" "unprognostic (3.15e-2)" "unprognostic (5.40e-3)" "unprognostic (1.93e-3)" "unprognostic (2.16e-1)" "unprognostic (1.87e-1)" "unprognostic (6.80e-2)" "unprognostic (1.73e-2)" "unprognostic (1.25e-2)" "potential prognostic favorable (3.26e-4)" "unprognostic (2.07e-2)" "unprognostic (6.90e-2)" "unprognostic (6.12e-3)" "unprognostic (1.02e-1)" "unprognostic (9.68e-2)" "unprognostic (6.19e-3)" "unprognostic (2.93e-1)" "unprognostic (6.30e-3)" SCG3 "FLJ90833, SgIII" ENSG00000104112 "Secretogranin III" Q8WXD2 15 51681492-51721026 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 155.7;pituitary gland: 37.2;retina: 52.5" "Cell type enhanced" "Detected in many" "Astrocytes: 114.5;Bergmann glia: 311.5;Brain inhibitory neurons: 80.3;Cone photoreceptor cells: 122.1;Corticotrophs: 143.0;Gonadotrophs: 80.0;Neuroendocrine cells: 150.1;Oligodendrocyte progenitor cells: 135.6;Other brain neurons: 110.1;Pancreatic islet cells: 704.9;Retinal bipolar cells: 79.7;Retinal horizontal cells: 78.1" "Cell type enhanced" "Detected in all" "Bergmann glia: 499.0" "Group enriched" "Detected in many" 10 "Glioblastoma Multiforme (TCGA): 72.3;Kidney Chromophobe (TCGA): 66.8;Pancreatic Adenocarcinoma (TCGA): 23.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Neuroblastoma: 62.1;thyroid cancer: 100.9" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Stomach - Gastric enteroendocrine cells, Testis - Spermatocytes, Thyroid gland - Parafollicular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006880, CAB033274, HPA053715" Enhanced Supported Supported Vesicles "Secreted in brain" "No annotated function" NA NA 2000000 "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 3 Vesicles "CAB033274: , HPA006880: , HPA053715: " "unprognostic (5.18e-2)" "unprognostic (2.81e-2)" "unprognostic (1.32e-1)" "unprognostic (4.39e-2)" "unprognostic (1.31e-2)" "unprognostic (4.68e-2)" "unprognostic (7.04e-3)" "unprognostic (1.78e-2)" "unprognostic (5.50e-2)" "unprognostic (1.74e-1)" "unprognostic (1.64e-2)" "unprognostic (3.21e-2)" "unprognostic (9.52e-3)" "unprognostic (2.61e-2)" "unprognostic (7.30e-2)" "unprognostic (4.53e-1)" "unprognostic (3.00e-1)" "unprognostic (2.35e-1)" "unprognostic (5.42e-3)" SCG5 "7B2, SGNE1, SgV" ENSG00000166922 "Secretogranin V" P05408 15 32641676-32697098 "Predicted secreted proteins" Transport "Chaperone, Neuropeptide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 246.1;choroid plexus: 347.2;pituitary gland: 386.3" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 124.5;Brain inhibitory neurons: 157.3;Choroid plexus epithelial cells: 37.7;Oligodendrocyte progenitor cells: 69.4;Oligodendrocytes: 89.9;Other brain neurons: 178.6" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Glioblastoma Multiforme (TCGA): 82.0;Pancreatic Adenocarcinoma (TCGA): 181.3;Thyroid Carcinoma (TCGA): 53.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 7 "thyroid cancer: 101.8" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Liver - Hepatocytes, Pancreas - Alpha cells, Pancreas - Beta cells, Stomach - Gastric enteroendocrine cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013136, HPA074618" Supported "Secreted to blood" Neuropeptide NA NA 24000 "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 98: Neurons - Neurotransmission & signaling" 16 "HPA013136: , HPA074618: " "unprognostic (1.20e-1)" "unprognostic (2.27e-1)" "unprognostic (1.77e-1)" "unprognostic (2.27e-2)" "unprognostic (6.07e-2)" "unprognostic (1.30e-2)" "unprognostic (9.45e-2)" "unprognostic (1.34e-2)" "unprognostic (1.81e-2)" "unprognostic (3.54e-3)" "unprognostic (5.27e-2)" "unprognostic (9.14e-2)" "unprognostic (1.36e-1)" "unprognostic (3.52e-1)" "unprognostic (4.60e-2)" "unprognostic (8.02e-2)" "unprognostic (8.39e-3)" "unprognostic (1.56e-2)" "unprognostic (7.35e-3)" "unprognostic (1.18e-2)" "unprognostic (3.71e-2)" "unprognostic (4.75e-1)" "unprognostic (1.50e-1)" "unprognostic (7.07e-2)" "unprognostic (8.21e-2)" "unprognostic (1.80e-1)" "unprognostic (5.70e-2)" "unprognostic (7.53e-2)" SCGB1A1 "CC10, CC16, CCSP, UGB" ENSG00000149021 "Secretoglobin family 1A member 1" P11684 11 62405103-62423195 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Phospholipase A2 inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "lung: 2893.8" "Group enriched" "Detected in some" 4 "Respiratory deuterosomal cells: 30129.5;Respiratory secretory cells: 77673.4" "Cell type enhanced" "Detected in some" "deep-layer near-projecting: 3.7;midbrain-derived inhibitory: 4.4" "Group enriched" "Detected in many" 7 "Lung Adenocarcinoma (TCGA): 939.5;Lung Squamous Cell Carcinoma (TCGA): 369.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 11 "Esophageal cancer: 174.9;Gallbladder cancer: 111.1;head and neck cancer: 48.1;pancreatic cancer: 75.7" "Lung - Respiratory ciliated cells, Prostate - Urothelial cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB025686, HPA031828" Enhanced "Secreted in other tissues" "Enzyme inhibitor" NA NA 6700000 "Cluster 13: Lung - Secretion" "Cluster 16: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 8 "CAB025686: , HPA031828: " "unprognostic (5.52e-2)" "unprognostic (3.40e-2)" "unprognostic (4.16e-1)" "unprognostic (1.13e-2)" "unprognostic (6.97e-2)" "unprognostic (2.17e-1)" "unprognostic (6.35e-3)" "unprognostic (2.66e-3)" "unprognostic (1.21e-2)" "unprognostic (3.85e-1)" "unprognostic (6.14e-2)" "unprognostic (4.11e-1)" "unprognostic (3.34e-2)" "unprognostic (7.26e-1)" "unprognostic (2.89e-3)" "unprognostic (2.69e-2)" "unprognostic (1.39e-1)" "unprognostic (1.35e-1)" SCGB1C1 RYD5 ENSG00000188076 "Secretoglobin family 1C member 1" Q8TD33 11 193078-194575 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "pancreas: 1.4;retina: 3.1;salivary gland: 1.0" "Cell type enriched" "Detected in some" 15 "Platelets: 28.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Ovary Serous Cystadenocarcinoma (TCGA): 1.5" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 32 "basophil: 4.9;neutrophil: 1.3" "Lineage enriched" "Detected in single" 50 "granulocytes: 4.9" "Not detected" "Not detected" "Secreted - unknown location" "No annotated function" NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 42: Retina - Visual perception" "Cluster 15: Non-specific - Transcription" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 47: Platelets - Hemostasis" "unprognostic (4.75e-2)" SCGB1C2 ENSG00000268320 "Secretoglobin family 1C member 2" P0DMR2 17 137569-139067 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "pancreas: 1.4" "Cell type enriched" "Detected in some" 32 "Platelets: 56.4" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Ovary Serous Cystadenocarcinoma (TCGA): 1.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" "No annotated function" NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 15: Kidney cancer - Membrane components" "Cluster 47: Platelets - Hemostasis" "unprognostic (1.33e-1)" SCGB1D1 "LIPA, LPHA, MGC71958" ENSG00000168515 "Secretoglobin family 1D member 1" O95968 11 62190216-62193539 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "cervix: 1.1" "Cell type enhanced" "Detected in some" "Epididymal principal cells: 3.2;Lacrimal acinar cells: 41.7;Neutrophils: 13.4;Plasma cells: 7.9;Retinal pigment epithelial cells: 4.3" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "Ovary Serous Cystadenocarcinoma (TCGA): 25.5;Uterine Corpus Endometrial Carcinoma (TCGA): 9.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" "No annotated function" NA NA 41000 "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 44: Plasma cells - Antibody production & secretion" 44 "unprognostic (1.30e-1)" "unprognostic (2.46e-1)" "unprognostic (2.85e-1)" SCGB1D2 "LIPB, LPHB" ENSG00000124935 "Secretoglobin family 1D member 2" O95969 11 62242239-62244812 "Cancer-related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "breast: 1148.9;cervix: 3767.2" "Cell type enhanced" "Detected in some" "Breast hormone-responsive cells: 457.1;Breast secretory cells: 891.7;Endometrial ciliated cells: 2764.0;Endometrial glandular cells: 3156.9;Endometrial luminal cells: 4582.6;Endometrial stromal cells: 541.5;Epididymal principal cells: 392.7;Fallopian tube ciliated cells: 738.7" "Group enriched" "Detected in some" 4 "choroid plexus epithelial cell: 6.7;committed oligodendrocyte precursor: 1.9;ependymal cell: 2.1" "Cancer enriched" "Detected in many" 8 "Breast Invasive Carcinoma (TCGA): 1570.0" "Region enhanced" "Detected in all" "choroid plexus: 21.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 17 "breast cancer: 256.6" "Adrenal gland - Adrenal medulla cells, Heart muscle - Cardiomyocytes, Prostate - Prostate glandular cells, Skeletal muscle - Skeletal myocytes, Skin - Eccrine sweat gland cells" HPA035318 Approved "Secreted in other tissues" "No annotated function" NA NA "Cluster 55: Breast - Lactation" "Cluster 3: Choroid plexus - Cilium" "Cluster 27: Breast cancer - Unknown function" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 6 "HPA035318: " "unprognostic (8.72e-2)" "unprognostic (1.56e-1)" "unprognostic (1.58e-2)" "unprognostic (2.61e-2)" "unprognostic (2.57e-1)" "unprognostic (1.08e-2)" "validated prognostic favorable (1.10e-6)" "validated prognostic favorable (6.41e-6)" "unprognostic (1.27e-1)" "unprognostic (3.87e-3)" "unprognostic (2.95e-1)" "unprognostic (4.50e-1)" "unprognostic (8.74e-2)" "unprognostic (1.07e-1)" "unprognostic (2.69e-1)" "unprognostic (1.53e-2)" "unprognostic (2.11e-2)" "unprognostic (1.57e-1)" "unprognostic (2.81e-2)" SCGB1D4 IIS ENSG00000197745 "Secretoglobin family 1D member 4" Q6XE38 11 62296281-62299075 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "cervix: 49.3;epididymis: 41.2;fallopian tube: 78.6" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 4188.6;Endometrial glandular cells: 847.1;Endometrial luminal cells: 483.6;Epididymal efferent duct absorptive cells: 809.1;Fallopian tube ciliated cells: 1180.3" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 19 "Uterine Corpus Endometrial Carcinoma (TCGA): 59.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Secreted in other tissues" "No annotated function" NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" "unprognostic (3.29e-1)" "unprognostic (6.61e-2)" "unprognostic (1.35e-1)" SCGB2A1 "LPHC, MGB2, MGC71973, UGB3" ENSG00000124939 "Secretoglobin family 2A member 1" O75556 11 62208673-62213943 "Cancer-related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "cervix: 1903.4;epididymis: 1293.8" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 2393.7;Endometrial glandular cells: 4106.3;Endometrial luminal cells: 1609.4;Endometrial stromal cells: 537.8;Epididymal efferent duct ciliated cells: 1198.7;Epididymal principal cells: 2331.5;Fallopian tube ciliated cells: 1206.5;Lacrimal acinar cells: 449.3" "Cell type enriched" "Detected in some" 10 "ependymal cell: 11.2" "Group enriched" "Detected in many" 5 "Ovary Serous Cystadenocarcinoma (TCGA): 328.1;Uterine Corpus Endometrial Carcinoma (TCGA): 897.5" "Region enhanced" "Detected in some" "medulla oblongata: 7.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 15.0" "Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Alpha cells, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" HPA034584 Enhanced Approved Vesicles "Secreted in other tissues" "No annotated function" NA NA 59000 "Cluster 22: Epididymis - Mixed function" "Cluster 46: Brainstem - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 8 Vesicles "HPA034584: " "unprognostic (2.29e-2)" "unprognostic (8.57e-2)" "unprognostic (3.43e-2)" "unprognostic (2.73e-2)" "unprognostic (9.98e-3)" "unprognostic (1.56e-2)" "unprognostic (4.13e-2)" "unprognostic (1.61e-2)" "unprognostic (9.36e-2)" "unprognostic (8.55e-2)" "unprognostic (1.17e-2)" "unprognostic (1.19e-1)" "unprognostic (2.24e-3)" "unprognostic (5.33e-3)" "unprognostic (1.00e-1)" "unprognostic (3.28e-1)" "unprognostic (5.96e-3)" "unprognostic (2.80e-1)" "unprognostic (1.20e-2)" "unprognostic (1.55e-2)" "unprognostic (1.23e-1)" "potential prognostic unfavorable (7.87e-6)" "unprognostic (9.39e-2)" "potential prognostic unfavorable (6.39e-4)" "unprognostic (1.77e-2)" SCGB2A2 "MGB1, MGC71974, PSBP1, UGB2" ENSG00000110484 "Secretoglobin family 2A member 2" Q13296 11 62270158-62273160 "Cancer-related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "breast: 2629.3;skin 1: 689.2" "Group enriched" "Detected in some" 7 "Breast hormone-responsive cells: 1297.6;Breast secretory cells: 3944.9" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 65 "Breast Invasive Carcinoma (TCGA): 5259.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 161 "breast cancer: 2165.1" "Skin - Eccrine sweat gland cells" "Region enhanced" "Detected in single" "cerebellum: 1.9" CAB026270 Enhanced "Secreted in female reproductive system" "No annotated function" NA NA "Cluster 55: Breast - Lactation" "Cluster 27: Breast cancer - Unknown function" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 1 "CAB026270: " "unprognostic (1.12e-1)" "unprognostic (2.28e-1)" "unprognostic (3.13e-1)" "unprognostic (2.66e-1)" "unprognostic (3.58e-2)" "unprognostic (8.31e-3)" "unprognostic (3.88e-1)" "unprognostic (1.96e-1)" "unprognostic (1.01e-2)" SCGB2B2 "SCGB4A2, SCGBL" ENSG00000205209 "Secretoglobin family 2B member 2" Q4G0G5 19 34590644-34677159 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "pancreas: 8.1" "Cell type enhanced" "Detected in many" "Early spermatids: 178.8;Myonuclei: 168.9;Sertoli cells: 156.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Heart muscle - Cardiomyocytes, Skin - Eccrine sweat gland cells, Testis - Early spermatids" HPA046806 Uncertain "Secreted in other tissues" "No annotated function" NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 6: Non-specific - Immune response" "Cluster 4: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 1 "HPA046806: " "unprognostic (6.46e-3)" "unprognostic (9.87e-2)" SCGB3A1 "HIN-1, HIN1, LU105, PnSP-2, UGRP2" ENSG00000161055 "Secretoglobin family 3A member 1" Q96QR1 5 180590105-180591499 "Plasma proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "cervix: 253.4;lung: 613.2;salivary gland: 829.3" "Group enriched" "Detected in many" 4 "Conjunctival goblet cells: 7815.5;Prostatic club cells: 13118.9;Respiratory deuterosomal cells: 11754.3;Respiratory secretory cells: 29303.3;Submucosal glandular cells: 27328.9" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 2.6;splatter: 1.8" "Cancer enriched" "Detected in many" 4 "Lung Adenocarcinoma (TCGA): 1901.6" "Group enriched" "Detected in many" 7 "choroid plexus: 24.2;hypothalamus: 11.7" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 52.0" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in single" "Gallbladder cancer: 1.0" "Breast - Breast glandular cells (progenitors), Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Ductal cells, Pituitary gland - Gonadotropes, Prostate - Urothelial cells, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "Secreted to blood" Cytokine NA NA 4200000 "Cluster 25: Non-specific - Unknown function" "Cluster 82: Salivary gland - Secretion" "Cluster 36: Choroid plexus - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 38: Secretory epithelial cells - Exocrine secretion" "unprognostic (4.67e-2)" "unprognostic (3.01e-3)" "unprognostic (2.24e-1)" "unprognostic (3.06e-3)" "unprognostic (1.15e-2)" "potential prognostic favorable (4.82e-5)" "unprognostic (2.56e-3)" "unprognostic (1.21e-3)" "unprognostic (1.82e-2)" "unprognostic (2.53e-3)" "unprognostic (2.09e-1)" "unprognostic (1.32e-1)" "unprognostic (1.96e-1)" "unprognostic (2.65e-1)" "unprognostic (5.27e-2)" "unprognostic (5.19e-2)" "unprognostic (3.66e-2)" "unprognostic (3.90e-2)" "unprognostic (5.95e-2)" "unprognostic (1.95e-1)" "unprognostic (2.93e-1)" "unprognostic (1.29e-1)" SCGB3A2 "LU103, PNSP1, UGRP1" ENSG00000164265 "Secretoglobin family 3A member 2" Q96PL1 5 147870682-147882191 "Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 122 "lung: 1193.6" "Cell type enriched" "Detected in some" 20 "Transitional alveolar cells: 15918.6" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "Lung Adenocarcinoma (TCGA): 1498.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 50 "basophil: 72.2" "Lineage enriched" "Detected in many" 50 "granulocytes: 72.2" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" "No annotated function" NA NA 780000 "Cluster 46: Basophils - Proteolysis" "Cluster 13: Lung - Secretion" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 3: Rhabdoid - Membrane components" "Cluster 81: Alveolar cells - Lung function" "unprognostic (1.93e-1)" "unprognostic (1.22e-1)" "unprognostic (7.68e-2)" "unprognostic (3.39e-2)" "unprognostic (3.64e-2)" "unprognostic (9.68e-2)" "unprognostic (1.55e-1)" "potential prognostic unfavorable (7.13e-5)" "unprognostic (1.10e-1)" "unprognostic (3.02e-1)" "unprognostic (2.71e-2)" "unprognostic (4.58e-2)" "unprognostic (3.96e-2)" "unprognostic (1.09e-1)" "unprognostic (9.20e-2)" "unprognostic (1.21e-1)" "unprognostic (1.64e-2)" "unprognostic (2.10e-2)" "unprognostic (1.25e-1)" "unprognostic (1.09e-1)" "unprognostic (1.22e-1)" "unprognostic (4.98e-1)" "unprognostic (3.61e-2)" "unprognostic (3.35e-3)" SCGN "CALBL, DJ501N12.8, SECRET, SEGN" ENSG00000079689 "Secretagogin, EF-hand calcium binding protein" O76038 6 25652201-25701783 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 42.4;pancreas: 44.4;pituitary gland: 35.4" "Group enriched" "Detected in some" 5 "Brain inhibitory neurons: 17.4;Other brain neurons: 49.5" "Cell type enriched" "Detected in some" 4 "cerebellar inhibitory: 199.3" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 50.6;Pancreatic Adenocarcinoma (TCGA): 56.6" "Group enriched" "Detected in many" 6 "cerebellum: 35.9;hippocampal formation: 28.2;hypothalamus: 92.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "Gastric cancer: 8.1;lung cancer: 19.8;Neuroblastoma: 6.9;prostate cancer: 9.7;thyroid cancer: 7.0" "Colon - Colon enteroendocrine cells, Pituitary gland - Somatotropes, Stomach - Gastric enteroendocrine cells, Testis - Spermatogonia" "Region enriched" "Detected in many" 16 "olfactory bulb: 82.0" "Region enriched" "Detected in many" 10 "olfactory bulb: 183.0" "CAB004005, HPA006641, CAB044060, CAB062563, CAB068232" Enhanced Supported Supported Cytosol "Intracellular and membrane" "No annotated function" NA NA "Cluster 70: Non-specific - Protein processing" "Cluster 16: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 109: Neurons - Neuronal signaling" 48 Cytosol "CAB004005: , CAB044060: , CAB062563: , CAB068232: , HPA006641: " "unprognostic (6.96e-2)" "unprognostic (3.28e-1)" "unprognostic (2.43e-1)" "unprognostic (5.09e-2)" "unprognostic (6.24e-2)" "validated prognostic favorable (1.29e-6)" "validated prognostic favorable (1.04e-5)" "unprognostic (1.55e-1)" "unprognostic (5.24e-3)" "unprognostic (5.19e-3)" "unprognostic (2.98e-1)" "unprognostic (4.84e-1)" "unprognostic (4.40e-1)" "unprognostic (1.42e-2)" "unprognostic (1.11e-1)" "unprognostic (4.58e-1)" "unprognostic (1.24e-1)" "unprognostic (3.00e-2)" "unprognostic (4.30e-2)" SCHIP1 SCHIP-1 ENSG00000151967 "Schwannomin interacting protein 1" P0DPB3 3 159839861-159897360 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "brain: 76.6;heart muscle: 74.5;skeletal muscle: 92.5;tongue: 86.3" "Cell type enhanced" "Detected in some" "Astrocytes: 73.5;Bergmann glia: 66.6;Brain excitatory neurons: 117.2;Brain inhibitory neurons: 47.9;Ependymal cells: 103.1;Microglia: 37.4;Oligodendrocyte progenitor cells: 97.2;Oligodendrocytes: 317.1;Other brain neurons: 38.8" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 25 "Glioblastoma Multiforme (TCGA): 115.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 6.9" "Group enriched" "Detected in many" 46 "dendritic cells: 6.9;granulocytes: 2.1" "Cancer enriched" "Detected in many" 8 "Neuroblastoma: 53.4" "Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003243, HPA069824" Uncertain Approved "Nucleoplasm,Nuclear bodies,Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 35: Neurons - Synaptic function & neurogenesis" 6 "Plasma membrane, Cell Junctions, Cytosol" "Nucleoplasm, Nuclear bodies" "HPA003243: , HPA069824: " "unprognostic (1.72e-2)" "unprognostic (1.31e-1)" "unprognostic (2.79e-2)" "unprognostic (2.13e-2)" "potential prognostic favorable (2.25e-4)" "unprognostic (2.65e-1)" "potential prognostic favorable (6.16e-6)" "unprognostic (3.51e-3)" "unprognostic (1.41e-2)" "unprognostic (1.27e-1)" "unprognostic (2.52e-1)" "unprognostic (3.56e-2)" "potential prognostic unfavorable (4.85e-4)" "unprognostic (3.98e-1)" "unprognostic (2.94e-2)" "unprognostic (3.37e-3)" "unprognostic (1.86e-2)" "unprognostic (6.92e-2)" "unprognostic (4.47e-1)" "unprognostic (1.02e-2)" "unprognostic (2.08e-1)" "unprognostic (2.03e-2)" SCIMP "C17orf87, DTFT5783, FLJ32580, MGC163426, MGC163428, UNQ5783" ENSG00000161929 "SLP adaptor and CSK interacting membrane protein" Q6UWF3 17 5208920-5234860 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 46.3" "Cell type enhanced" "Detected in many" "B-cells: 129.5;Cardiomyocytes: 64.7;cDC: 56.1;Hofbauer cells: 32.5;Kupffer cells: 223.4;Macrophages: 67.9;monocytes: 90.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "classical monocyte: 110.6;intermediate monocyte: 239.0;memory B-cell: 146.0;myeloid DC: 84.1;naive B-cell: 124.7;non-classical monocyte: 267.0" "Group enriched" "Detected in all" 8 "B-cells: 146.0;dendritic cells: 84.1;monocytes: 267.0" "Cancer enhanced" "Detected in many" "Leukemia: 11.8;lymphoma: 16.5" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Lung - Macrophages, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Spleen - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA006117 Enhanced NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 55: Lymphoma - Immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 3 "HPA006117: " "unprognostic (9.25e-3)" "unprognostic (1.11e-1)" "unprognostic (6.80e-2)" "unprognostic (3.84e-2)" "unprognostic (1.10e-1)" "unprognostic (1.24e-2)" "unprognostic (3.15e-1)" "unprognostic (3.86e-2)" "unprognostic (3.87e-1)" "unprognostic (1.43e-1)" "unprognostic (1.12e-1)" "unprognostic (3.97e-3)" "unprognostic (1.33e-1)" "potential prognostic favorable (2.33e-4)" "unprognostic (7.25e-2)" "unprognostic (6.80e-2)" "unprognostic (2.99e-1)" "unprognostic (1.42e-1)" "unprognostic (8.35e-2)" "unprognostic (1.01e-3)" "unprognostic (3.13e-3)" "unprognostic (2.77e-2)" "unprognostic (7.42e-3)" "potential prognostic favorable (7.32e-4)" "unprognostic (2.13e-2)" "unprognostic (1.30e-1)" "unprognostic (2.15e-1)" "unprognostic (8.44e-3)" "unprognostic (1.34e-1)" SCIN KIAA1905 ENSG00000006747 Scinderin Q9Y6U3 7 12570577-12660182 "Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 43.6;kidney: 44.0;placenta: 73.1" "Cell type enhanced" "Detected in many" "Enterocytes: 553.9;Hofbauer cells: 240.6;Loop of henle epithelial cells: 170.6;Microglia: 170.7;Ocular epithelial cells: 210.7;Renal collecting duct intercalated cells: 731.0;Renal collecting duct principal cells: 321.9;Renal connecting tubule cells: 330.9;Respiratory ionocytes: 172.7" "Group enriched" "Detected in many" 7 "central nervous system macrophage: 213.2;ependymal cell: 163.0" "Group enriched" "Detected in many" 4 "Kidney Chromophobe (TCGA): 190.5;Kidney Renal Papillary Cell Carcinoma (TCGA): 95.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA020518, HPA024264" Enhanced Approved "Plasma membrane,Cytosol" No No 5500000 "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 6 "Plasma membrane" Cytosol "HPA020518: , HPA024264: " "unprognostic (1.85e-2)" "unprognostic (2.40e-2)" "unprognostic (1.77e-1)" "unprognostic (3.29e-1)" "unprognostic (1.36e-1)" "unprognostic (3.09e-2)" "unprognostic (5.45e-2)" "unprognostic (1.38e-1)" "unprognostic (2.49e-1)" "unprognostic (1.87e-2)" "unprognostic (6.47e-2)" "unprognostic (5.36e-3)" "unprognostic (1.16e-2)" "unprognostic (2.83e-1)" "unprognostic (1.91e-1)" "unprognostic (1.87e-1)" "unprognostic (4.26e-2)" "unprognostic (4.68e-2)" "unprognostic (3.41e-1)" "unprognostic (1.38e-1)" "unprognostic (6.88e-2)" "unprognostic (8.90e-2)" "unprognostic (1.17e-1)" "unprognostic (4.07e-2)" "potential prognostic unfavorable (5.86e-4)" "unprognostic (2.40e-1)" "unprognostic (1.60e-1)" "unprognostic (5.04e-2)" "unprognostic (3.42e-2)" "unprognostic (1.95e-1)" SCLT1 "FLJ30655, hCAP-1A" ENSG00000151466 "Sodium channel and clathrin linker 1" Q96NL6 4 128864921-129093600 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 1017.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 66.3" "Group enriched" "Detected in all" 5 "granulocytes: 66.3;monocytes: 31.3" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036560, HPA036561" Approved Approved "Microtubules,Basal body,Cytosol" NA Yes "Cluster 7: Non-specific - Innate immune response" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 25: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 24: Neutrophils - Innate immunity signal integration" 12 "Basal body, Cytosol" Microtubules "HPA036560: , HPA036561: " "unprognostic (1.40e-1)" "unprognostic (2.47e-1)" "unprognostic (1.29e-1)" "unprognostic (8.46e-2)" "unprognostic (1.71e-1)" "unprognostic (6.09e-2)" "unprognostic (3.55e-1)" "unprognostic (3.45e-2)" "unprognostic (1.60e-1)" "unprognostic (5.25e-3)" "unprognostic (5.74e-2)" "unprognostic (2.71e-1)" "unprognostic (3.80e-2)" "potential prognostic unfavorable (4.82e-4)" "unprognostic (1.59e-1)" "unprognostic (2.30e-3)" "unprognostic (9.26e-3)" "unprognostic (1.72e-1)" "unprognostic (2.13e-2)" "unprognostic (6.80e-2)" "unprognostic (2.10e-1)" "unprognostic (8.17e-2)" "potential prognostic unfavorable (2.65e-4)" "unprognostic (2.24e-3)" "unprognostic (1.58e-2)" "unprognostic (5.70e-3)" "unprognostic (1.36e-2)" "unprognostic (1.92e-1)" "unprognostic (1.66e-1)" "unprognostic (7.93e-3)" "unprognostic (8.67e-2)" SCLY SCL ENSG00000132330 "Selenocysteine lyase" Q96I15 2 238060924-238099413 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lyase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 37.5" "Group enriched" "Detected in some" 6 "Astrocytes: 31.6;Bergmann glia: 25.8;Brain excitatory neurons: 35.3;Brain inhibitory neurons: 32.6;Choroid plexus epithelial cells: 40.3;Early spermatids: 45.0;Ependymal cells: 29.1;Late spermatids: 86.6;Microglia: 36.0;Oligodendrocyte progenitor cells: 36.2;Oligodendrocytes: 54.0;Other brain neurons: 22.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020190, HPA055760" Uncertain Enhanced "Golgi apparatus" NA NA 200000 "Cluster 25: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 8 "Golgi apparatus" "HPA020190: , HPA055760: " "unprognostic (1.19e-1)" "unprognostic (2.58e-2)" "unprognostic (4.71e-2)" "unprognostic (9.10e-2)" "unprognostic (1.73e-1)" "unprognostic (3.56e-1)" "unprognostic (2.31e-1)" "unprognostic (9.03e-2)" "unprognostic (1.04e-2)" "unprognostic (3.05e-1)" "potential prognostic favorable (1.92e-6)" "unprognostic (1.54e-3)" "unprognostic (5.43e-2)" "unprognostic (4.94e-2)" "unprognostic (8.53e-2)" "unprognostic (2.39e-2)" "unprognostic (1.66e-1)" "unprognostic (5.27e-2)" "unprognostic (1.50e-2)" "unprognostic (7.97e-2)" "unprognostic (2.19e-1)" "unprognostic (2.80e-2)" "unprognostic (3.34e-1)" "unprognostic (2.17e-1)" "unprognostic (1.74e-1)" "unprognostic (3.59e-1)" "unprognostic (6.25e-2)" "unprognostic (2.10e-2)" "unprognostic (4.58e-2)" "unprognostic (1.03e-2)" "unprognostic (1.48e-1)" SCMH1 Scml3 ENSG00000010803 "Scm polycomb group protein homolog 1" Q96GD3 1 41027202-41242306 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Developmental protein, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048898, HPA053292" Supported "Nucleoplasm,Nuclear bodies,Cytosol" No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 35: Non-specific - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 37: Non-specific - mRNA processing" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 15 Nucleoplasm "Nuclear bodies, Cytosol" "HPA048898: , HPA053292: " "unprognostic (2.16e-3)" "unprognostic (1.89e-1)" "unprognostic (3.38e-1)" "unprognostic (6.37e-2)" "unprognostic (2.33e-2)" "unprognostic (3.62e-1)" "unprognostic (3.97e-2)" "unprognostic (7.77e-2)" "unprognostic (4.01e-1)" "unprognostic (1.06e-2)" "unprognostic (7.65e-3)" "unprognostic (1.67e-2)" "potential prognostic favorable (1.81e-5)" "potential prognostic unfavorable (1.05e-4)" "unprognostic (3.39e-3)" "unprognostic (1.26e-2)" "unprognostic (9.42e-2)" "unprognostic (2.63e-2)" "unprognostic (1.68e-1)" "unprognostic (4.94e-2)" "unprognostic (3.87e-2)" "unprognostic (1.17e-1)" "unprognostic (2.99e-1)" "unprognostic (1.34e-1)" "unprognostic (7.06e-2)" "unprognostic (1.88e-1)" "unprognostic (2.17e-1)" "unprognostic (5.81e-2)" "unprognostic (1.18e-1)" "unprognostic (2.41e-1)" "unprognostic (6.35e-2)" SCML1 ENSG00000047634 "Scm polycomb group protein like 1" Q9UN30 X 17737449-17754988 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 932.6;Sertoli cells: 689.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 19.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "HPA035270, HPA035271, HPA061397" Enhanced Approved Nucleoplasm NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 47: Testis - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 3: Early primary spermatocytes - Early meiosis" 10 Nucleoplasm "HPA035270: , HPA035271: , HPA061397: " "unprognostic (2.50e-1)" "unprognostic (3.12e-2)" "unprognostic (6.51e-2)" "unprognostic (1.55e-2)" "unprognostic (1.52e-1)" "unprognostic (3.91e-2)" "unprognostic (6.72e-2)" "unprognostic (2.43e-1)" "unprognostic (3.06e-1)" "unprognostic (2.05e-1)" "unprognostic (1.02e-1)" "unprognostic (2.01e-1)" "unprognostic (3.38e-3)" "potential prognostic unfavorable (2.86e-4)" "unprognostic (1.39e-1)" "unprognostic (1.88e-1)" "unprognostic (1.89e-1)" "unprognostic (4.26e-2)" "unprognostic (1.16e-1)" "unprognostic (5.12e-1)" "unprognostic (1.40e-1)" "unprognostic (2.06e-2)" "unprognostic (7.40e-2)" "unprognostic (7.27e-2)" "unprognostic (2.13e-2)" "unprognostic (1.34e-2)" "unprognostic (1.89e-1)" "unprognostic (3.35e-1)" "unprognostic (1.03e-1)" "unprognostic (1.26e-2)" "unprognostic (1.35e-1)" SCML2 ENSG00000102098 "Scm polycomb group protein like 2" Q9UQR0 X 18239313-18354688 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 10.8" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 61.9;Differentiating spermatogonia: 72.1;Early primary spermatocytes: 53.6;Hematopoietic stem cells: 77.2;Megakaryocyte progenitors: 44.1;Megakaryocyte-Erythroid progenitors: 42.1;pDCs: 41.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 7.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "plasmacytoid DC: 3.8" "Lineage enriched" "Detected in single" 6 "dendritic cells: 3.8" "Low cancer specificity" "Detected in all" "Stomach - Fibroblasts, Testis - Spermatocytes, Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA001662, HPA064713" Enhanced Approved Nucleoli,Cytosol NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 6: Leukemia - Signal transduction" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 15 "Nucleoli, Cytosol" "HPA001662: , HPA064713: " "unprognostic (1.01e-1)" "unprognostic (2.56e-2)" "unprognostic (8.88e-2)" "unprognostic (2.28e-2)" "unprognostic (3.88e-2)" "unprognostic (2.06e-2)" "unprognostic (1.81e-1)" "unprognostic (4.19e-2)" "validated prognostic unfavorable (1.08e-4)" "validated prognostic unfavorable (3.11e-4)" "unprognostic (2.01e-1)" "unprognostic (1.44e-2)" "unprognostic (1.87e-3)" "unprognostic (2.25e-1)" "unprognostic (1.10e-1)" "unprognostic (2.25e-2)" "unprognostic (5.20e-3)" "unprognostic (7.57e-3)" "unprognostic (2.14e-1)" "unprognostic (1.73e-1)" "unprognostic (5.79e-2)" SCML4 dJ47M23.1 ENSG00000146285 "Scm polycomb group protein like 4" Q8N228 6 107702154-107824317 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 9.5;lymphoid tissue: 11.3" "Cell type enhanced" "Detected in many" "B-cells: 89.0;Early spermatids: 171.5;Innate lymphoid cells: 331.3;Lactotrophs: 150.3;Late spermatids: 280.3;Neutrophils: 75.6;NK-cells: 317.6;T-cells: 385.4;Thymocytes: 256.6;Thyrotrophs: 141.6" "Cell type enriched" "Detected in many" 19 "leukocyte: 300.3" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 6.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "gdT-cell: 48.3;MAIT T-cell: 47.8;memory CD4 T-cell: 75.0;memory CD8 T-cell: 65.7;naive CD4 T-cell: 69.2;naive CD8 T-cell: 59.6;NK-cell: 53.5" "Group enriched" "Detected in many" 6 "NK-cells: 53.5;T-cells: 75.0" "Cancer enhanced" "Detected in some" "skin cancer: 8.6" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Colon - T-cells, Lung - T-cells, Minor Salivary Gland - T-cells, Pituitary gland - Lactotropes, Prostate - T-cells, Skin - T-cells, Stomach - T-cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA063326, HPA065958" Approved Approved Nucleoplasm NA NA "Cluster 11: T-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" Nucleoplasm "HPA063326: , HPA065958: " "potential prognostic favorable (1.67e-4)" "unprognostic (3.01e-1)" "unprognostic (4.56e-2)" "unprognostic (5.90e-2)" "unprognostic (3.92e-3)" "potential prognostic favorable (1.85e-5)" "unprognostic (4.62e-2)" "unprognostic (1.44e-1)" "unprognostic (2.09e-3)" "unprognostic (4.33e-2)" "unprognostic (6.62e-2)" "unprognostic (4.36e-2)" "unprognostic (5.27e-1)" "unprognostic (8.42e-2)" "unprognostic (2.23e-2)" SCN10A "hPN3, Nav1.8, PN3, SNS" ENSG00000185313 "Sodium voltage-gated channel alpha subunit 10" Q9Y5Y9 3 38696802-38816286 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Early spermatids: 3.2;Epicardial cells: 2.3;Foveolar cells: 2.1;Late primary spermatocytes: 2.3;Late spermatids: 4.6;Retinal amacrine cells: 1.4" "Low cell type specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA040337 Approved "Connecting piece,Flagellar centriole" NA NA "Cluster 51: Myeloma - Immunoglobulins" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "Connecting piece, Flagellar centriole" "HPA040337: " SCN11A "NaN, Nav1.9, SCN12A, SNS-2" ENSG00000168356 "Sodium voltage-gated channel alpha subunit 11" Q9UI33 3 38845764-39052157 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Disease variant, FDA approved drug targets, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 2.8;placenta: 1.8;urinary bladder: 2.0" "Cell type enhanced" "Detected in many" "Astrocytes: 42.8;Bergmann glia: 48.9;Differentiating spermatogonia: 38.9;Early primary spermatocytes: 49.7;Ependymal cells: 31.1;Papillary tip epithelial cells: 169.8;Prostatic hillock cells: 35.6;Undifferentiated spermatogonia: 57.1" "Cell type enhanced" "Detected in all" "Bergmann glia: 60.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enteroendocrine cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA036746, HPA036747" Uncertain NA NA "Cluster 5: Spleen - Immune response" "Cluster 39: Astrocytes - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 82: Dendritic cells - Antigen presentation" "HPA036746: , HPA036747: " "unprognostic (2.52e-1)" SCN1A "FEB3, GEFSP2, HBSCI, NAC1, Nav1.1, SCN1, SMEI" ENSG00000144285 "Sodium voltage-gated channel alpha subunit 1" P35498 2 165984641-166149214 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Autism, Autism spectrum disorder, Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 7.9;retina: 3.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 178.2;Brain excitatory neurons: 336.0;Brain inhibitory neurons: 430.0;Ependymal cells: 573.7;Fallopian tube ciliated cells: 190.3;Oligodendrocyte progenitor cells: 835.0;Other brain neurons: 230.2;Pituicytes/FSCs: 233.7;Retinal bipolar cells: 155.3;Retinal ganglion cells: 421.0" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in single" 7 "Glioblastoma Multiforme (TCGA): 2.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078664 Supported "Nucleoplasm,Nuclear bodies,Plasma membrane" NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 109: Neurons - Neuronal signaling" 1 "Nucleoplasm, Plasma membrane" "Nuclear bodies" "HPA078664: " "unprognostic (4.38e-1)" "unprognostic (7.03e-3)" SCN1B ENSG00000105711 "Sodium voltage-gated channel beta subunit 1" Q07699 19 35030470-35040449 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Ion transport, Sodium transport, Transport" "Atrial fibrillation, Brugada syndrome, Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 271.5;skeletal muscle: 550.8;tongue: 212.7" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 80.5;Hofbauer cells: 64.1;Innate lymphoid cells: 108.5;Kupffer cells: 90.2;Myonuclei: 58.4;Neutrophils: 47.4;Platelets: 260.3;Retinal bipolar cells: 48.3;Retinal ganglion cells: 50.2;Thymic myoid cells: 99.3" "Cell type enhanced" "Detected in all" "cerebellar inhibitory: 205.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "thyroid cancer: 23.5" "Minor Salivary Gland - Endothelial cells, Spleen - Macrophages" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 536.8" "Secreted in other tissues" Transport NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 72: Neuronal - Signal transduction" "Cluster 109: Neurons - Neuronal signaling" 1 "unprognostic (2.34e-2)" "unprognostic (1.81e-1)" "unprognostic (8.87e-2)" "unprognostic (4.12e-2)" "unprognostic (1.08e-1)" "unprognostic (7.72e-2)" "unprognostic (3.28e-3)" "unprognostic (1.84e-1)" "unprognostic (4.04e-2)" "unprognostic (6.10e-2)" "unprognostic (3.26e-3)" "unprognostic (4.37e-3)" "potential prognostic favorable (1.85e-4)" "unprognostic (8.76e-3)" "unprognostic (1.06e-1)" "unprognostic (8.55e-2)" "unprognostic (1.23e-1)" "unprognostic (7.77e-2)" "unprognostic (1.11e-1)" "unprognostic (3.24e-3)" "unprognostic (2.22e-2)" "potential prognostic favorable (3.80e-5)" "unprognostic (1.91e-1)" "unprognostic (3.29e-2)" "unprognostic (1.91e-2)" "unprognostic (2.67e-1)" "unprognostic (1.24e-2)" "unprognostic (6.25e-3)" "unprognostic (1.95e-1)" "unprognostic (3.72e-2)" "unprognostic (7.88e-2)" SCN2A "HBSCI, HBSCII, Nav1.2, SCN2A1, SCN2A2" ENSG00000136531 "Sodium voltage-gated channel alpha subunit 2" Q99250 2 165194993-165392310 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "brain: 67.0" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 682.9;Brain inhibitory neurons: 466.7;Cone photoreceptor cells: 250.5;Corticotrophs: 184.4;Distal convoluted tubule cells: 751.3;Lactotrophs: 214.7;Oligodendrocyte progenitor cells: 265.9;Other brain neurons: 368.5;Papillary tip epithelial cells: 237.1;Renal collecting duct intercalated cells: 361.1;Renal collecting duct principal cells: 359.5;Renal connecting tubule cells: 1172.9" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 2.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 5.8" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells, Pituitary gland - Lactotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022567 Enhanced NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 14: Neurons - Synaptic function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 13 "CAB022567: " "unprognostic (5.41e-1)" "unprognostic (3.49e-1)" "unprognostic (1.29e-3)" "unprognostic (1.74e-1)" "unprognostic (1.38e-1)" "unprognostic (1.99e-1)" "unprognostic (1.25e-1)" SCN2B ENSG00000149575 "Sodium voltage-gated channel beta subunit 2" O60939 11 118162806-118176639 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Transport" "Atrial fibrillation, Brugada syndrome, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 48.3" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 27.9;Brain inhibitory neurons: 34.1;Epididymal basal cells: 9.1;Myonuclei: 7.5;Other brain neurons: 28.0;Retinal amacrine cells: 28.0;Retinal ganglion cells: 15.5;Retinal horizontal cells: 10.0" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 2.5;Thyroid Carcinoma (TCGA): 2.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Minor Salivary Gland - Fibroblasts, Skeletal muscle - Skeletal myocytes, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 98: Neurons - Neurotransmission & signaling" "unprognostic (3.26e-1)" "unprognostic (1.03e-1)" "unprognostic (1.97e-1)" "unprognostic (1.21e-1)" "unprognostic (2.25e-1)" SCN3A Nav1.3 ENSG00000153253 "Sodium voltage-gated channel alpha subunit 3" Q9NY46 2 165087526-165204050 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.6;lymphoid tissue: 3.7" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 255.4;Brain inhibitory neurons: 346.4;Cone photoreceptor cells: 304.3;Corticotrophs: 245.0;Lactotrophs: 218.5;Neuroendocrine cells: 158.6;Oligodendrocyte progenitor cells: 384.6;Other brain neurons: 262.9;Renal collecting duct principal cells: 182.9;Renal connecting tubule cells: 146.9;Somatotrophs: 159.7;Thymocytes: 505.6;Thyrotrophs: 171.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in single" "Glioblastoma Multiforme (TCGA): 3.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 30 "memory B-cell: 13.3;naive B-cell: 15.4" "Lineage enriched" "Detected in single" 32 "B-cells: 15.4" "Cancer enhanced" "Detected in many" "lung cancer: 9.7" "Adipose subcutaneous - Smooth muscle cells, Colon - Colon enteroendocrine cells, Pituitary gland - Lactotropes, Spleen - B-cells (Spleen), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA035396 Uncertain NA NA "Cluster 34: B-cells - Unknown function" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 1: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 35: Neurons - Synaptic function & neurogenesis" 2 "HPA035396: " "unprognostic (5.07e-3)" "unprognostic (3.91e-2)" "unprognostic (1.28e-1)" "potential prognostic favorable (3.01e-4)" "unprognostic (1.31e-2)" "unprognostic (4.18e-1)" SCN3B "HSA243396, SCNB3" ENSG00000166257 "Sodium voltage-gated channel beta subunit 3" Q9NY72 11 123629187-123655244 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Atrial fibrillation, Brugada syndrome, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 73.3;pituitary gland: 26.6" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 74.5;Brain excitatory neurons: 100.9;Brain inhibitory neurons: 80.6;Corticotrophs: 40.7;Lactotrophs: 178.4;Late spermatids: 50.9;Lymphatic endothelial cells: 175.2;Other brain neurons: 96.6;Retinal amacrine cells: 146.3;Somatotrophs: 72.1;Thyrotrophs: 139.4" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in some" 4 "Glioblastoma Multiforme (TCGA): 6.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 12 "Neuroblastoma: 18.0" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal medulla cells, Pituitary gland - Lactotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078632 Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 128 "Plasma membrane, Cytosol" Vesicles "HPA078632: " "unprognostic (7.64e-3)" "unprognostic (3.89e-2)" "unprognostic (1.77e-3)" "unprognostic (3.80e-1)" "unprognostic (4.31e-2)" "unprognostic (1.94e-3)" "unprognostic (2.30e-1)" "unprognostic (4.97e-2)" SCN4A "HYKPP, HYPP, Nav1.4, SkM1" ENSG00000007314 "Sodium voltage-gated channel alpha subunit 4" P35499 17 63938554-63972918 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Congenital myasthenic syndrome, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "skeletal muscle: 128.7;tongue: 50.4" "Cell type enriched" "Detected in some" 6 "Myonuclei: 170.5" "Cell type enriched" "Detected in some" 27 "fibroblast: 36.6" "Cancer enhanced" "Detected in some" "Thyroid Carcinoma (TCGA): 3.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 2.1;Sarcoma: 6.5" "Pituitary gland - Somatotropes, Testis - Late spermatids" "Not detected" "Not detected" "Region enhanced" "Detected in single" "spinal cord: 1.3" HPA070997 Uncertain "Golgi apparatus" NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" "Golgi apparatus" "HPA070997: " "unprognostic (2.36e-3)" "unprognostic (1.53e-1)" "potential prognostic favorable (1.24e-7)" "unprognostic (3.10e-1)" "unprognostic (3.59e-1)" SCN4B LQT10 ENSG00000177098 "Sodium voltage-gated channel beta subunit 4" Q8IWT1 11 118133377-118152888 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Transport" "Atrial fibrillation, Disease variant, FDA approved drug targets, Long QT syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.4;skeletal muscle: 28.5;tongue: 53.0" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 17.5;Brain inhibitory neurons: 29.7;Breast myoepithelial cells: 9.5;Ependymal cells: 21.0;Epididymal efferent duct ciliated cells: 10.1;Late spermatids: 14.0;Pericytes: 45.4;Respiratory ciliated cells: 12.8;Retinal ganglion cells: 23.2;Vascular smooth muscle cells: 9.8" "Cell type enhanced" "Detected in many" "medium spiny neuron: 71.0" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 10.7;Kidney Renal Clear Cell Carcinoma (TCGA): 10.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 2.1" "Liver - Hepatic stellate cells, Minor Salivary Gland - Fibroblasts, Pituitary gland - Fibroblasts, Prostate - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Region enriched" "Detected in all" 11 "basal ganglia: 816.5" "Region enriched" "Detected in many" 4 "basal ganglia: 174.4" HPA017293 Approved NA NA "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 65: Non-specific - Unknown function" "Cluster 110: Mural cells - ECM organization" 1 "HPA017293: " "unprognostic (1.06e-1)" "unprognostic (2.44e-1)" "unprognostic (6.02e-2)" "unprognostic (4.30e-1)" "unprognostic (6.49e-2)" "unprognostic (1.20e-1)" "unprognostic (2.64e-1)" "validated prognostic favorable (9.91e-8)" "validated prognostic favorable (6.39e-5)" "unprognostic (1.70e-1)" "potential prognostic favorable (7.76e-4)" "unprognostic (2.14e-2)" "unprognostic (2.28e-2)" "unprognostic (3.42e-1)" "unprognostic (4.42e-3)" "unprognostic (8.81e-2)" "unprognostic (1.52e-1)" "unprognostic (7.65e-2)" "unprognostic (7.59e-2)" "unprognostic (1.31e-1)" "unprognostic (6.86e-2)" SCN5A "CDCD2, CMD1E, CMPD2, HB1, HB2, HBBD, HH1, ICCD, IVF, LQT3, Nav1.5, PFHB1, SSS1" ENSG00000183873 "Sodium voltage-gated channel alpha subunit 5" Q14524 3 38548057-38649687 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sodium transport, Transport" "Calmodulin-binding, Ion channel, Sodium channel, Voltage-gated channel" "Atrial fibrillation, Brugada syndrome, Cardiomyopathy, Disease variant, FDA approved drug targets, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 26 "heart muscle: 49.7" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 229.0;Cone photoreceptor cells: 51.8;Myosatellite cells: 20.0;Neutrophil progenitors: 68.2;Neutrophils: 41.9;Oocytes: 27.6;Pituicytes/FSCs: 21.7;Retinal amacrine cells: 19.9" "Cell type enhanced" "Detected in many" "eccentric medium spiny neuron: 37.8;fibroblast: 22.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 5.5;Sarcoma: 4.2" "Breast - Breast myoepithelial cells, Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Pituitary gland - Undifferentiated cells (Pituitary gland)" "Group enriched" "Detected in many" 5 "amygdala: 3.1;basal ganglia: 10.1;hypothalamus: 6.0" "Region enhanced" "Detected in many" "basal ganglia: 6.6" HPA063346 Supported "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 10 "Plasma membrane" "Nucleoplasm, Nucleoli" "HPA063346: " "unprognostic (9.16e-2)" "unprognostic (1.53e-1)" SCN7A "NaG, Nav2.1, Nav2.2, SCN6A" ENSG00000136546 "Sodium voltage-gated channel alpha subunit 7" Q01118 2 166403573-166611482 "FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 33.1;ovary: 37.4" "Cell type enriched" "Detected in many" 4 "Schwann cells: 1625.0" "Cell type enhanced" "Detected in many" "fibroblast: 109.9;splatter: 129.4;thalamic excitatory: 115.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 7 "Rhabdoid: 19.2" "Adrenal gland - Fibroblasts, Colon - Enteric glia cells, Pituitary gland - Fibroblasts, Prostate - Fibroblasts, Spleen - Fibroblasts_2" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 10.0" HPA072715 Approved Approved "Plasma membrane" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 61: Schwann cells & Melanocytes - Mixed function" 1 "Plasma membrane" "HPA072715: " "unprognostic (1.60e-1)" "unprognostic (3.05e-1)" "unprognostic (4.85e-2)" "unprognostic (3.85e-2)" "unprognostic (1.25e-1)" "unprognostic (2.11e-1)" "unprognostic (2.54e-2)" "unprognostic (1.85e-3)" "unprognostic (2.43e-1)" "unprognostic (2.73e-2)" "unprognostic (1.02e-1)" "unprognostic (6.16e-2)" "unprognostic (2.71e-2)" "unprognostic (3.82e-1)" "unprognostic (1.23e-1)" "unprognostic (9.27e-2)" "unprognostic (3.98e-2)" "unprognostic (4.69e-2)" "unprognostic (8.06e-2)" SCN8A "CerIII, CIAT, MED, NaCh6, Nav1.6, PN4" ENSG00000196876 "Sodium voltage-gated channel alpha subunit 8" Q9UQD0 12 51590266-51812864 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 16.9;pituitary gland: 6.3;retina: 7.3" "Cell type enhanced" "Detected in many" "Bergmann glia: 152.4;Brain excitatory neurons: 367.3;Brain inhibitory neurons: 321.4;Corticotrophs: 194.7;Gonadotrophs: 255.9;Lactotrophs: 245.8;Oligodendrocyte progenitor cells: 137.2;Other brain neurons: 185.7;Retinal amacrine cells: 157.0;Retinal bipolar cells: 120.7;Retinal ganglion cells: 166.1;Retinal horizontal cells: 140.2;Somatotrophs: 250.8;Thyrotrophs: 256.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022169, HPA043937, HPA073590" Approved "Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 35: Neurons - Synaptic function & neurogenesis" 1 "Plasma membrane" "Vesicles, Cell Junctions" "CAB022169: , HPA043937: , HPA073590: " "unprognostic (1.37e-1)" "unprognostic (2.40e-1)" "unprognostic (7.00e-2)" "potential prognostic favorable (2.44e-4)" "unprognostic (7.21e-2)" "unprognostic (8.57e-3)" "unprognostic (3.78e-1)" "potential prognostic favorable (3.92e-4)" "unprognostic (1.68e-2)" "unprognostic (2.49e-1)" "unprognostic (2.75e-1)" "unprognostic (2.10e-1)" "unprognostic (2.70e-1)" SCN9A "ETHA, Nav1.7, NE-NA, NENA, PN1" ENSG00000169432 "Sodium voltage-gated channel alpha subunit 9" Q15858 2 166195185-166376001 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 5.7" "Cell type enhanced" "Detected in many" "Corticotrophs: 202.7;Ependymal cells: 167.2;Hofbauer cells: 347.3;Macrophages: 142.0;Oligodendrocyte progenitor cells: 299.5;Other brain neurons: 285.9;pDCs: 172.6;Respiratory ionocytes: 243.8;Retinal ganglion cells: 146.8;Schwann cells: 176.1;Sertoli cells: 810.0;Somatotrophs: 155.0" "Cell type enhanced" "Detected in all" "oligodendrocyte precursor cell: 408.5" "Cancer enhanced" "Detected in some" "Lung Squamous Cell Carcinoma (TCGA): 4.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 16 "plasmacytoid DC: 23.6" "Lineage enriched" "Detected in single" 26 "dendritic cells: 23.6" "Cancer enhanced" "Detected in many" "Rhabdoid: 44.7" "Adrenal gland - Adrenal medulla cells, Kidney - Proximal tubular cells, Testis - Sertoli cells" "Region enriched" "Detected in many" 5 "hypothalamus: 9.3" "Low region specificity" "Detected in many" "CAB013679, HPA061843" Uncertain Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 1 "Plasma membrane, Actin filaments, Focal adhesion sites" "CAB013679: , HPA061843: " "unprognostic (3.00e-1)" "unprognostic (1.04e-1)" "unprognostic (5.89e-2)" "unprognostic (1.14e-2)" "unprognostic (2.70e-2)" "unprognostic (7.62e-2)" "unprognostic (2.59e-2)" "unprognostic (4.04e-1)" "unprognostic (3.27e-2)" "unprognostic (1.61e-2)" "unprognostic (2.96e-2)" "unprognostic (1.02e-1)" "unprognostic (7.58e-3)" "unprognostic (1.78e-1)" SCNM1 MGC3180 ENSG00000163156 "Sodium channel modifier 1" Q9BWG6 1 151156664-151170296 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 119.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052439, HPA054324" Uncertain Approved Nucleoplasm NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 156 Nucleoplasm "HPA052439: , HPA054324: " "unprognostic (1.41e-1)" "unprognostic (1.35e-1)" "unprognostic (8.41e-2)" "unprognostic (4.23e-2)" "unprognostic (1.85e-1)" "unprognostic (3.04e-1)" "unprognostic (5.05e-2)" "potential prognostic favorable (6.49e-4)" "unprognostic (2.39e-1)" "unprognostic (8.45e-2)" "unprognostic (4.08e-3)" "unprognostic (6.57e-2)" "potential prognostic unfavorable (3.80e-4)" "potential prognostic unfavorable (2.23e-4)" "unprognostic (2.90e-2)" "unprognostic (8.75e-3)" "unprognostic (6.26e-3)" "unprognostic (8.77e-3)" "unprognostic (1.31e-1)" "potential prognostic favorable (3.63e-4)" "unprognostic (1.03e-1)" "unprognostic (1.76e-1)" "unprognostic (5.16e-2)" "unprognostic (3.91e-1)" "unprognostic (3.01e-3)" "unprognostic (1.10e-1)" "unprognostic (1.14e-1)" "unprognostic (3.99e-1)" "unprognostic (1.94e-1)" "unprognostic (1.29e-1)" "unprognostic (1.18e-1)" SCNN1A "ENaCalpha, SCNN1" ENSG00000111319 "Sodium channel epithelial 1 subunit alpha" P37088 12 6346843-6377730 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 184.9;salivary gland: 149.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 393.4;Alveolar cells type 2: 299.0;Conjunctival goblet cells: 371.8;Endometrial luminal cells: 370.9;Esophageal apical cells: 424.6;Goblet cells: 372.4;Renal collecting duct intercalated cells: 288.1;Respiratory secretory cells: 296.1;Salivary duct cells: 508.6;Salivary ionocytes: 441.9;Transitional alveolar cells: 295.7" "Cell type enriched" "Detected in some" 51 "choroid plexus epithelial cell: 140.0" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 391.1" "Region enriched" "Detected in some" 18 "choroid plexus: 243.0" "Immune cell enhanced" "Detected in some" "neutrophil: 1.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate basal glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA012743 Enhanced Uncertain Vesicles,Acrosome,Annulus NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 36: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 10 "Vesicles, Annulus" Acrosome "HPA012743: " "unprognostic (2.62e-1)" "unprognostic (2.33e-1)" "unprognostic (7.00e-2)" "unprognostic (2.80e-1)" "unprognostic (4.49e-2)" "unprognostic (3.20e-1)" "unprognostic (1.75e-2)" "unprognostic (1.61e-1)" "unprognostic (1.19e-2)" "unprognostic (1.21e-2)" "unprognostic (1.92e-2)" "unprognostic (1.19e-2)" "unprognostic (3.10e-3)" "unprognostic (2.15e-1)" "unprognostic (3.39e-2)" "unprognostic (1.40e-1)" "unprognostic (1.08e-1)" "unprognostic (3.93e-3)" "unprognostic (1.62e-1)" "validated prognostic unfavorable (2.14e-4)" "validated prognostic unfavorable (6.66e-4)" "unprognostic (1.51e-1)" "unprognostic (1.33e-1)" "unprognostic (7.18e-3)" "unprognostic (1.13e-1)" "unprognostic (1.38e-1)" "unprognostic (2.11e-1)" "unprognostic (6.85e-2)" "unprognostic (1.42e-1)" SCNN1B ENaCbeta ENSG00000168447 "Sodium channel epithelial 1 subunit beta" P51168 16 23278231-23381294 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 80.6;intestine: 89.1;vagina: 55.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 192.9;Colonocytes: 251.8;Conjunctival goblet cells: 223.3;Esophageal apical cells: 990.3;Esophageal suprabasal cells: 198.5;Foveolar cells: 149.6;Renal connecting tubule cells: 163.1;Respiratory ionocytes: 718.8;Respiratory secretory cells: 204.4;Salivary duct cells: 428.5;Salivary ionocytes: 414.7;Transitional alveolar cells: 168.1" "Cell type enhanced" "Detected in some" "upper rhombic lip: 3.7" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 54.0;Lung Adenocarcinoma (TCGA): 39.2" "Region enriched" "Detected in single" 9 "cerebellum: 2.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "Myeloma: 32.1;Sarcoma: 36.5;thyroid cancer: 9.6" "Kidney - Intercalated cells, Prostate - Prostate basal glandular cells, Stomach - Gastric mucous cells" "Region enriched" "Detected in single" 5 "cerebellum: 1.0" "Low region specificity" "Detected in many" HPA015612 Uncertain NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 35: Non-specific - DNA binding" "Cluster 54: Non-specific - Transcription" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 11 "HPA015612: " "unprognostic (7.74e-3)" "unprognostic (1.12e-2)" "unprognostic (7.36e-2)" "potential prognostic favorable (8.52e-4)" "unprognostic (1.33e-1)" "unprognostic (3.45e-2)" "unprognostic (2.07e-2)" "unprognostic (8.17e-3)" "unprognostic (1.70e-2)" "unprognostic (6.87e-2)" "potential prognostic unfavorable (8.64e-4)" "unprognostic (1.82e-2)" "unprognostic (1.60e-1)" "potential prognostic favorable (3.14e-4)" "unprognostic (3.88e-1)" "unprognostic (4.16e-3)" "unprognostic (9.89e-3)" "unprognostic (2.15e-1)" "unprognostic (2.34e-1)" "unprognostic (3.00e-1)" "unprognostic (3.14e-1)" "unprognostic (1.36e-1)" "unprognostic (8.10e-3)" "unprognostic (1.95e-1)" "unprognostic (2.02e-1)" "unprognostic (5.95e-2)" "unprognostic (1.30e-2)" "unprognostic (3.48e-2)" SCNN1D "dNaCh, ENaCdelta" ENSG00000162572 "Sodium channel epithelial 1 subunit delta" P51172 1 1280436-1292029 "FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.6;testis: 34.7" "Cell type enhanced" "Detected in many" "Astrocytes: 13.1;Early spermatids: 16.9;Ependymal cells: 9.9;Esophageal apical cells: 13.0;Esophageal suprabasal cells: 12.6;Oligodendrocyte progenitor cells: 11.6;Proximal tubule cells: 13.8;Retinal ganglion cells: 11.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" HPA026884 Enhanced Supported "Plasma membrane,Actin filaments" NA NA "Cluster 67: Testis - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 88: Proximal tubular cells - Transmembrane transport" 3 "Plasma membrane, Actin filaments" "HPA026884: " "unprognostic (1.54e-3)" "unprognostic (4.77e-2)" "unprognostic (1.33e-1)" "unprognostic (1.32e-1)" "unprognostic (9.07e-3)" "unprognostic (1.41e-1)" "unprognostic (1.01e-1)" "potential prognostic favorable (1.56e-4)" "unprognostic (2.23e-2)" "potential prognostic unfavorable (2.99e-5)" "unprognostic (1.70e-1)" "unprognostic (2.17e-1)" "unprognostic (2.31e-2)" "unprognostic (2.56e-1)" "unprognostic (1.82e-1)" "unprognostic (1.39e-1)" "unprognostic (6.73e-2)" "unprognostic (6.71e-2)" "potential prognostic favorable (5.55e-4)" "unprognostic (1.18e-3)" "unprognostic (1.01e-1)" "unprognostic (9.91e-2)" "unprognostic (9.99e-2)" "unprognostic (1.55e-1)" "unprognostic (9.71e-3)" "unprognostic (2.04e-1)" "unprognostic (3.17e-1)" SCNN1G "ENaCgamma, SCNEG" ENSG00000166828 "Sodium channel epithelial 1 subunit gamma" P51170 16 23182745-23216883 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 39.6" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 103.4;Conjunctival goblet cells: 78.6;Esophageal apical cells: 184.0;Renal collecting duct principal cells: 252.9;Renal connecting tubule cells: 305.3;Respiratory ionocytes: 142.2;Respiratory secretory cells: 121.9;Salivary basal cells: 70.6;Salivary duct cells: 190.9;Salivary ionocytes: 88.7;Transitional alveolar cells: 86.0" "Cell type enhanced" "Detected in some" "hippocampal dentate gyrus: 9.7;upper rhombic lip: 12.1" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 15.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Bone cancer: 13.8" "Breast - Breast glandular cells, Lung - Alveolar cells type 1, Minor Salivary Gland - Minor salivary gland ductal cells, Pancreas - Ductal cells, Prostate - Prostate basal glandular cells, Stomach - Gastric mucous cells" "Region enriched" "Detected in single" 13 "cerebellum: 2.5" "Not detected" "Not detected" HPA071194 Supported "Nucleoplasm,Plasma membrane,Primary cilium,Primary cilium transition zone" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 35: Non-specific - DNA binding" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 6 "Plasma membrane" "Nucleoplasm, Primary cilium, Primary cilium transition zone" "HPA071194: " "unprognostic (6.04e-3)" "unprognostic (1.00e-1)" "unprognostic (2.17e-3)" "unprognostic (4.60e-3)" "unprognostic (5.29e-2)" "unprognostic (2.15e-2)" "unprognostic (7.73e-3)" "potential prognostic unfavorable (7.37e-6)" "unprognostic (3.87e-2)" "unprognostic (1.44e-1)" "unprognostic (9.68e-2)" "unprognostic (2.06e-1)" "unprognostic (2.32e-2)" "unprognostic (1.99e-1)" "unprognostic (1.85e-2)" "unprognostic (1.65e-1)" "unprognostic (9.55e-2)" "unprognostic (5.08e-2)" "unprognostic (1.61e-1)" "unprognostic (3.22e-1)" SCO1 SCOD1 ENSG00000133028 "Synthesis of cytochrome C oxidase 1" O75880 17 10672474-10698375 "Disease related genes, Human disease related genes, Predicted membrane proteins" Chaperone "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 157.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021565, HPA021579" Enhanced NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 42: Non-specific - Unknown function" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 12 "HPA021565: , HPA021579: " "unprognostic (8.74e-2)" "unprognostic (5.26e-3)" "unprognostic (7.22e-2)" "unprognostic (2.67e-2)" "unprognostic (3.11e-2)" "unprognostic (3.11e-3)" "unprognostic (8.67e-3)" "unprognostic (7.38e-2)" "unprognostic (6.44e-2)" "unprognostic (9.98e-3)" "potential prognostic favorable (8.56e-6)" "unprognostic (3.56e-2)" "unprognostic (4.52e-3)" "unprognostic (3.80e-2)" "unprognostic (4.36e-2)" "unprognostic (1.91e-3)" "unprognostic (3.88e-1)" "unprognostic (1.88e-1)" "unprognostic (1.08e-1)" "unprognostic (2.28e-1)" "unprognostic (1.23e-1)" "unprognostic (4.57e-2)" "unprognostic (2.08e-1)" "unprognostic (2.04e-2)" "unprognostic (1.16e-1)" "unprognostic (1.97e-1)" "unprognostic (2.43e-2)" "unprognostic (4.88e-2)" "unprognostic (1.02e-1)" "unprognostic (1.72e-3)" "unprognostic (1.31e-1)" SCO2 "MYP6, SCO1L" ENSG00000284194 "Synthesis of cytochrome C oxidase 2" O43819 22 50523568-50526461 "Disease related genes, Human disease related genes, Predicted membrane proteins" Chaperone "Cardiomyopathy, Disease variant, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Colonocytes: 114.1;Esophageal suprabasal cells: 134.4" "Cell type enhanced" "Detected in all" "ependymal cell: 60.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046943, HPA056254" Uncertain Supported Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 28: Liver & Adrenal gland - Secretion" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 66: Non-specific - Mitochondria" "Cluster 97: Non-specific - Cellular respiration" 12 Mitochondria "HPA046943: , HPA056254: " "unprognostic (1.03e-1)" "unprognostic (8.74e-3)" "unprognostic (3.84e-2)" "unprognostic (2.75e-1)" "unprognostic (1.72e-2)" "unprognostic (9.39e-2)" "unprognostic (3.74e-1)" "unprognostic (6.02e-3)" "unprognostic (7.83e-2)" "potential prognostic unfavorable (9.11e-4)" "unprognostic (1.09e-1)" "unprognostic (1.09e-1)" "unprognostic (1.52e-3)" "unprognostic (2.45e-1)" "unprognostic (1.45e-1)" "unprognostic (6.72e-2)" "unprognostic (2.28e-1)" "unprognostic (2.51e-1)" "unprognostic (2.96e-1)" "unprognostic (1.06e-1)" "unprognostic (1.84e-1)" "unprognostic (1.44e-1)" "unprognostic (2.31e-1)" "unprognostic (2.77e-2)" "unprognostic (3.55e-2)" "unprognostic (1.05e-1)" "unprognostic (1.06e-1)" "unprognostic (1.58e-2)" SCOC "HRIHFB2072, SCOCO, UNC-69" ENSG00000153130 "Short coiled-coil protein" Q9UIL1 4 140257286-140385728 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 662.2;Esophageal apical cells: 484.9;Parietal cells: 302.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA061198, HPA070321" Approved Approved "Nucleoplasm,Golgi apparatus" NA NA 7700 "Cluster 3: Non-specific - Nuclear processes" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 27: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 18 "Nucleoplasm, Golgi apparatus" "HPA061198: , HPA070321: " "unprognostic (6.92e-3)" "unprognostic (3.64e-2)" "potential prognostic unfavorable (2.49e-4)" "unprognostic (2.12e-2)" "unprognostic (5.60e-2)" "unprognostic (6.45e-3)" "potential prognostic unfavorable (3.58e-4)" "unprognostic (3.12e-2)" "unprognostic (5.27e-3)" "unprognostic (2.65e-2)" "validated prognostic favorable (6.05e-7)" "validated prognostic favorable (2.09e-4)" "unprognostic (6.55e-3)" "unprognostic (3.80e-3)" "unprognostic (1.27e-1)" "unprognostic (3.33e-3)" "unprognostic (1.30e-1)" "unprognostic (1.52e-1)" "unprognostic (3.00e-2)" "unprognostic (2.28e-1)" "unprognostic (1.48e-3)" "unprognostic (2.03e-1)" "unprognostic (7.33e-2)" "unprognostic (2.28e-1)" "unprognostic (1.02e-1)" "unprognostic (2.12e-1)" "unprognostic (7.86e-2)" "unprognostic (1.19e-1)" "unprognostic (1.55e-1)" "unprognostic (1.01e-1)" "unprognostic (7.21e-2)" SCP2 ENSG00000116171 "Sterol carrier protein 2" P22307 1 52927276-53051698 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Lipid transport, Transport" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1042.5" "Cell type enhanced" "Detected in all" "Breast lactating cells: 764.6;Enterocytes: 748.6;Esophageal apical cells: 1043.5;Hepatocytes: 1656.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "HPA027101, HPA027135, HPA027317" Supported Supported Nucleoplasm,Peroxisomes NA NA 280000 "Cluster 25: Non-specific - Unknown function" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 37: Non-specific - mRNA processing" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 6 Peroxisomes Nucleoplasm "HPA027101: , HPA027135: , HPA027317: " "potential prognostic favorable (1.14e-5)" "unprognostic (5.35e-2)" "unprognostic (2.89e-1)" "unprognostic (1.92e-1)" "potential prognostic favorable (3.31e-4)" "unprognostic (9.33e-2)" "unprognostic (5.39e-2)" "unprognostic (3.43e-1)" "unprognostic (8.15e-2)" "unprognostic (1.03e-1)" "potential prognostic favorable (2.14e-10)" "unprognostic (6.43e-2)" "unprognostic (2.61e-2)" "unprognostic (6.46e-3)" "unprognostic (3.72e-3)" "unprognostic (1.37e-1)" "unprognostic (3.38e-2)" "unprognostic (2.10e-1)" "unprognostic (1.24e-1)" "unprognostic (1.71e-1)" "unprognostic (4.60e-2)" "unprognostic (9.65e-3)" "unprognostic (1.28e-2)" "unprognostic (2.40e-1)" "unprognostic (3.27e-1)" "unprognostic (4.51e-2)" "unprognostic (9.18e-3)" "unprognostic (2.04e-2)" "unprognostic (2.49e-1)" "unprognostic (1.87e-1)" "unprognostic (1.49e-1)" SCP2D1 "C20orf79, dJ1068E13.2, HSD22" ENSG00000132631 "SCP2 sterol binding domain containing 1" Q9UJQ7 20 18813783-18814378 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 620 "testis: 62.0" "Group enriched" "Detected in some" 29 "Early spermatids: 1214.1;Late spermatids: 1250.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" SCPEP1 RISC ENSG00000121064 "Serine carboxypeptidase 1" Q9HB40 17 56978129-57006768 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 283.0" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 387.7;Breast myoepithelial cells: 320.3;Conjunctival goblet cells: 251.5;Endometrial secretory cells: 426.2;Parietal cells: 261.6;Salivary basal cells: 264.2;Submucosal glandular cells: 340.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 319.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Lung - Macrophages, Stomach - Parietal cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039102, HPA057200" Enhanced Approved "Golgi apparatus" "Secreted to blood" Enzyme NA NA 17000 "Cluster 29: Non-specific - Unknown function" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 4 "Golgi apparatus" "HPA039102: , HPA057200: " "unprognostic (3.17e-1)" "unprognostic (8.26e-2)" "unprognostic (2.14e-1)" "unprognostic (2.00e-3)" "unprognostic (4.53e-2)" "unprognostic (7.24e-2)" "unprognostic (9.41e-3)" "unprognostic (2.38e-1)" "unprognostic (7.67e-2)" "unprognostic (2.51e-1)" "unprognostic (2.04e-2)" "unprognostic (3.18e-1)" "unprognostic (2.69e-2)" "potential prognostic unfavorable (5.18e-5)" "unprognostic (7.24e-2)" "potential prognostic favorable (7.24e-4)" "unprognostic (2.73e-2)" "unprognostic (2.05e-1)" "unprognostic (1.52e-1)" "unprognostic (2.40e-1)" "unprognostic (9.22e-2)" "unprognostic (3.66e-2)" "unprognostic (8.44e-2)" "unprognostic (3.33e-1)" "unprognostic (2.15e-1)" "unprognostic (9.72e-2)" "unprognostic (1.54e-1)" "unprognostic (1.26e-2)" "unprognostic (2.54e-1)" "unprognostic (2.06e-1)" "potential prognostic unfavorable (3.08e-4)" SCRG1 SCRG-1 ENSG00000164106 "Stimulator of chondrogenesis 1" O75711 4 173384701-173406380 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 15.6;brain: 37.5" "Cell type enhanced" "Detected in many" "Astrocytes: 84.2;Bergmann glia: 50.2;Hepatic stellate cells: 45.2;Melanocytes: 40.5;Müller glia: 132.3;Oligodendrocyte progenitor cells: 174.2;Oligodendrocytes: 109.0;Schwann cells: 45.3;Sertoli cells: 109.2;Smooth muscle cells: 52.9" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 538.1;oligodendrocyte precursor cell: 238.8" "Cancer enriched" "Detected in some" 8 "Glioblastoma Multiforme (TCGA): 50.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in some" "Brain cancer: 2.0;skin cancer: 2.2" "Adipose subcutaneous - Smooth muscle cells, Lung - Fibroblasts_2, Prostate - Smooth muscle cells, Spleen - Smooth muscle cells, Stomach - Fibroblasts, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012882 Approved "Secreted in brain" "No annotated function" NA NA 190000 "Cluster 20: Non-specific - DNA binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 4 "HPA012882: " "unprognostic (3.92e-2)" "unprognostic (1.48e-1)" "unprognostic (1.02e-1)" "unprognostic (2.33e-2)" "unprognostic (1.78e-2)" "unprognostic (2.05e-3)" "unprognostic (9.32e-3)" "unprognostic (2.86e-2)" "unprognostic (2.07e-1)" "unprognostic (1.17e-2)" "unprognostic (1.07e-1)" SCRIB "KIAA0147, SCRB1, Vartul" ENSG00000180900 "Scribble planar cell polarity protein" Q14160 8 143790920-143815773 "Disease related genes, Predicted intracellular proteins" Differentiation "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 38.8;Bergmann glia: 16.6;Distal convoluted tubule cells: 16.5;Ependymal cells: 21.4;Loop of henle epithelial cells: 13.7;Oligodendrocyte progenitor cells: 16.9;Oligodendrocytes: 20.7;Papillary tip epithelial cells: 18.6;Renal collecting duct intercalated cells: 18.7;Renal collecting duct principal cells: 16.2;Renal connecting tubule cells: 14.2;Tuft cells: 34.6" "Cell type enhanced" "Detected in all" "astrocyte: 52.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015463, CAB022081, HPA023557, HPA064312" Supported Enhanced "Nucleoplasm,Plasma membrane,Cell Junctions,Rods & Rings" NA NA "Cluster 68: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 28: Astrocytes - Homeostasis & neuron support" 72 "Plasma membrane, Cell Junctions" "Nucleoplasm, Rods & Rings" "CAB015463: , CAB022081: , HPA023557: , HPA064312: " "unprognostic (8.67e-2)" "unprognostic (1.08e-1)" "unprognostic (2.13e-1)" "potential prognostic unfavorable (2.73e-5)" "unprognostic (1.34e-1)" "unprognostic (2.25e-1)" "unprognostic (1.40e-1)" "unprognostic (1.73e-3)" "unprognostic (2.32e-2)" "unprognostic (1.16e-1)" "unprognostic (1.55e-1)" "unprognostic (3.85e-2)" "unprognostic (4.93e-2)" "unprognostic (7.79e-3)" "unprognostic (1.28e-2)" "unprognostic (1.28e-1)" "unprognostic (1.08e-1)" "unprognostic (3.26e-2)" "unprognostic (6.80e-2)" "unprognostic (2.92e-1)" "unprognostic (9.97e-2)" "unprognostic (7.49e-2)" "unprognostic (9.48e-3)" "unprognostic (3.06e-2)" "unprognostic (2.75e-1)" "unprognostic (2.50e-1)" "unprognostic (2.31e-2)" "unprognostic (1.10e-2)" "unprognostic (2.15e-1)" "unprognostic (1.64e-1)" "unprognostic (6.66e-2)" SCRN1 KIAA0193 ENSG00000136193 "Secernin 1" Q12765 7 29920104-29990289 "Enzymes, Predicted intracellular proteins" Exocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 157.9" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Spleen - B-cells (Spleen), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024517 Enhanced Approved Cytosol No No 330000 "Cluster 29: Non-specific - Unknown function" "Cluster 27: Cerebellum - Synaptic function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 7 Cytosol "HPA024517: " "unprognostic (4.83e-1)" "unprognostic (1.06e-3)" "unprognostic (1.55e-1)" "unprognostic (1.33e-2)" "unprognostic (1.91e-1)" "unprognostic (2.63e-1)" "unprognostic (1.03e-1)" "potential prognostic unfavorable (6.17e-5)" "unprognostic (4.01e-1)" "unprognostic (5.07e-3)" "unprognostic (3.75e-2)" "unprognostic (2.37e-1)" "unprognostic (5.26e-2)" "potential prognostic unfavorable (3.65e-4)" "unprognostic (1.77e-1)" "unprognostic (7.46e-2)" "unprognostic (3.09e-2)" "unprognostic (1.18e-1)" "unprognostic (5.97e-1)" "potential prognostic unfavorable (4.37e-4)" "unprognostic (2.13e-2)" "unprognostic (1.25e-2)" "unprognostic (1.60e-1)" "unprognostic (3.37e-1)" "unprognostic (3.75e-1)" "unprognostic (4.36e-3)" "unprognostic (9.56e-2)" "unprognostic (4.26e-2)" "unprognostic (3.08e-1)" "unprognostic (4.12e-1)" "unprognostic (1.42e-2)" SCRN2 ENSG00000141295 "Secernin 2" Q96FV2 17 47837692-47841289 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 131.3;Epididymal efferent duct absorptive cells: 80.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022934, HPA023434" Enhanced Supported "Nucleoplasm,Golgi apparatus" NA NA 330000 "Cluster 45: Eosinophils - Unknown function" "Cluster 72: Kidney - Transmembrane transport" "Cluster 21: Non-specific - Metabolism" "Cluster 27: Breast cancer - Unknown function" "Cluster 1: Enterocytes - Absorption and Digestion" 4 Nucleoplasm "Golgi apparatus" "HPA022934: , HPA023434: " "unprognostic (2.10e-1)" "unprognostic (4.59e-2)" "unprognostic (1.75e-3)" "unprognostic (1.97e-2)" "unprognostic (1.45e-1)" "unprognostic (1.13e-2)" "unprognostic (1.09e-2)" "unprognostic (1.70e-2)" "unprognostic (3.88e-2)" "unprognostic (1.23e-1)" "potential prognostic favorable (1.26e-4)" "unprognostic (1.68e-1)" "potential prognostic favorable (3.92e-4)" "unprognostic (2.24e-3)" "unprognostic (1.54e-1)" "unprognostic (1.63e-1)" "unprognostic (2.28e-2)" "unprognostic (3.90e-1)" "unprognostic (6.82e-2)" "unprognostic (3.65e-2)" "unprognostic (2.76e-2)" "unprognostic (1.89e-2)" "unprognostic (4.68e-1)" "unprognostic (1.14e-1)" "unprognostic (5.02e-3)" "unprognostic (2.87e-2)" "unprognostic (3.20e-1)" "unprognostic (4.89e-3)" "unprognostic (1.33e-1)" "unprognostic (3.89e-2)" "unprognostic (1.58e-3)" SCRN3 FLJ23142 ENSG00000144306 "Secernin 3" Q0VDG4 2 174395730-174429575 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 112.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skeletal muscle - Skeletal myocytes, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034689, HPA034690" Approved Approved Vesicles,Cytosol NA NA 27000 "Cluster 24: Non-specific - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 2 "Vesicles, Cytosol" "HPA034689: , HPA034690: " "unprognostic (3.49e-3)" "unprognostic (1.19e-2)" "unprognostic (1.29e-1)" "unprognostic (4.01e-3)" "unprognostic (3.01e-2)" "unprognostic (8.25e-3)" "unprognostic (2.44e-1)" "unprognostic (6.18e-2)" "unprognostic (2.64e-1)" "unprognostic (1.36e-2)" "potential prognostic favorable (1.95e-7)" "unprognostic (1.86e-2)" "unprognostic (2.49e-1)" "unprognostic (5.03e-2)" "unprognostic (4.32e-2)" "unprognostic (1.85e-1)" "unprognostic (1.89e-1)" "unprognostic (2.08e-1)" "unprognostic (2.20e-1)" "unprognostic (5.67e-2)" "unprognostic (2.80e-2)" "unprognostic (1.25e-1)" "unprognostic (2.58e-2)" "unprognostic (1.34e-1)" "unprognostic (3.00e-2)" "unprognostic (1.98e-1)" "unprognostic (6.50e-3)" "unprognostic (1.73e-1)" "unprognostic (9.60e-2)" "potential prognostic unfavorable (1.07e-4)" "unprognostic (1.86e-1)" SCRT1 "DKFZp547F072, ZNF898" ENSG00000261678 "Scratch family transcriptional repressor 1" Q9BWW7 8 144330565-144336482 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 25 "brain: 76.8" "Group enriched" "Detected in some" 9 "Brain excitatory neurons: 19.9;Brain inhibitory neurons: 19.6;Other brain neurons: 15.3" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in single" "Glioblastoma Multiforme (TCGA): 1.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Neuroblastoma: 6.5" "Adrenal gland - Adrenal medulla cells, Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045265 Uncertain Supported "Nuclear bodies" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" "Nuclear bodies" "HPA045265: " "unprognostic (1.61e-2)" SCRT2 ZNF898B ENSG00000215397 "Scratch family transcriptional repressor 2" Q9NQ03 20 661596-675802 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 30 "brain: 3.9;retina: 3.6" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "cerebellar inhibitory: 6.4" "Cancer enriched" "Detected in single" 5 "Glioblastoma Multiforme (TCGA): 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 9 "Neuroblastoma: 7.0" "Pancreas - Alpha cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA067697 Approved Nucleoplasm NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 37: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" Nucleoplasm "HPA067697: " "unprognostic (4.94e-2)" SCT ENSG00000070031 Secretin P09683 11 626309-627181 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "intestine: 41.5" "Group enriched" "Detected in some" 11 "Neuroendocrine cells: 764.0;pDCs: 280.1" "Cell type enhanced" "Detected in some" "endothelial cell: 2.7;fibroblast: 1.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 137 "plasmacytoid DC: 126.8" "Lineage enriched" "Detected in single" 137 "dendritic cells: 126.8" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA050961 Enhanced "Secreted to blood" Hormone NA NA 571000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 6: Non-specific - Immune response" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" 2 "HPA050961: " "unprognostic (2.49e-1)" "unprognostic (8.72e-2)" "unprognostic (9.61e-2)" "potential prognostic unfavorable (3.03e-4)" "unprognostic (3.48e-1)" "unprognostic (4.52e-2)" "unprognostic (8.55e-2)" "unprognostic (2.65e-2)" "unprognostic (8.21e-3)" "unprognostic (1.36e-2)" "unprognostic (1.53e-1)" "unprognostic (1.98e-1)" "unprognostic (1.08e-1)" "unprognostic (8.73e-3)" "unprognostic (2.87e-2)" SCTR ENSG00000080293 "Secretin receptor" P47872 2 119439843-119525301 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 25.0;pancreas: 64.3" "Cell type enhanced" "Detected in many" "Adipocytes: 84.2;Alveolar cells type 2: 75.8;Cholangiocytes: 45.9;Epicardial cells: 56.9;Gastric progenitor cells: 60.2;Loop of henle epithelial cells: 137.8;Pancreatic duct cells: 520.1;Renal collecting duct intercalated cells: 49.3" "Cell type enhanced" "Detected in some" "CGE interneuron: 5.9;mammillary body: 8.3" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 14.5;Pancreatic Adenocarcinoma (TCGA): 31.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "liver cancer: 1.1" "Heart muscle - Cardiomyocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA007269 Uncertain NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 37: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" "HPA007269: " "unprognostic (4.62e-1)" "unprognostic (3.18e-2)" "unprognostic (3.55e-2)" "unprognostic (2.70e-2)" "unprognostic (3.04e-1)" "unprognostic (1.55e-2)" "unprognostic (1.29e-2)" "unprognostic (8.25e-2)" "unprognostic (5.59e-2)" "unprognostic (1.28e-1)" "unprognostic (1.18e-1)" "unprognostic (2.19e-1)" "unprognostic (3.40e-1)" "unprognostic (7.57e-3)" "unprognostic (3.76e-2)" SCUBE1 ENSG00000159307 "Signal peptide, CUB domain and EGF like domain containing 1" Q8IWY4 22 43197280-43343372 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 24.6" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 13.4;Alveolar cells type 1: 26.3;Epididymal clear cells: 14.3;Extravillous trophoblasts: 54.1;Leydig cells: 21.0;Ovarian stromal cells: 34.7;Peritubular myoid cells: 68.1;Pituitary stem cells: 34.3" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 28.1;deep-layer corticothalamic and 6b: 16.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 5.5" "Prostate - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA003190 Approved "Secreted to blood" "No annotated function" NA NA 2170000 17000000 "Cluster 75: Ovary - Mixed function" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 66: Non-specific - Mitochondria" "Cluster 94: Gonadal somatic cells - Mixed function" "HPA003190: " "unprognostic (1.97e-2)" "unprognostic (5.57e-2)" "unprognostic (6.23e-3)" "unprognostic (1.73e-1)" "unprognostic (1.26e-3)" "potential prognostic favorable (9.43e-4)" "unprognostic (2.53e-1)" "unprognostic (1.48e-3)" "unprognostic (2.61e-2)" "unprognostic (9.34e-3)" "unprognostic (1.91e-1)" "unprognostic (1.36e-2)" SCUBE2 "Cegb1, Cegf1, FLJ16792" ENSG00000175356 "Signal peptide, CUB domain and EGF like domain containing 2" Q9NQ36 11 9019476-9138114 "Predicted intracellular proteins, Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 46.0" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 101.6;Breast hormone-responsive cells: 139.7;Epididymal basal cells: 104.0;Epididymal clear cells: 75.5;Prostatic club cells: 207.2;Prostatic hillock cells: 93.9;Retinal horizontal cells: 100.2;Somatotrophs: 114.2;Urothelial cells: 174.6" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Breast Invasive Carcinoma (TCGA): 189.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "non-classical monocyte: 1.0" "Lineage enriched" "Detected in single" 6 "monocytes: 1.0" "Group enriched" "Detected in some" 5 "breast cancer: 27.2;skin cancer: 7.3" "Adrenal gland - Fibroblasts, Colon - Enteric glia cells, Spleen - Fibroblasts_2, Stomach - Chief cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Fibroblasts" "Group enriched" "Detected in some" 4 "olfactory bulb: 4.6;thalamus: 2.7" "Low region specificity" "Detected in all" "HPA006353, HPA029871" Uncertain "Secreted to blood" "Developmental protein" NA NA 4400000 "Cluster 22: Epididymis - Mixed function" "Cluster 35: Non-specific - DNA binding" "Cluster 27: Breast cancer - Unknown function" "Cluster 69: Urothelial cells - Basic cellular functions" "HPA006353: , HPA029871: " "unprognostic (4.49e-2)" "unprognostic (1.21e-3)" "unprognostic (4.21e-1)" "potential prognostic favorable (9.46e-5)" "unprognostic (1.92e-1)" "unprognostic (3.27e-1)" "unprognostic (3.58e-1)" "unprognostic (2.92e-1)" "unprognostic (2.95e-2)" "unprognostic (1.10e-1)" "unprognostic (2.11e-1)" "unprognostic (5.15e-2)" "unprognostic (8.91e-3)" "unprognostic (2.41e-2)" "unprognostic (8.72e-3)" "unprognostic (1.78e-2)" "unprognostic (1.91e-2)" "unprognostic (3.36e-1)" "unprognostic (3.38e-2)" "unprognostic (7.03e-2)" "potential prognostic unfavorable (4.90e-4)" "unprognostic (4.80e-2)" "unprognostic (7.23e-3)" "unprognostic (1.96e-1)" "unprognostic (5.91e-2)" "unprognostic (6.23e-2)" "unprognostic (1.71e-1)" "potential prognostic unfavorable (6.11e-4)" "unprognostic (1.94e-1)" "unprognostic (4.29e-2)" "unprognostic (1.54e-1)" SCUBE3 "CEGF3, FLJ34743" ENSG00000146197 "Signal peptide, CUB domain and EGF like domain containing 3" Q8IX30 6 35213956-35253079 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "blood vessel: 42.6;thyroid gland: 25.9" "Cell type enriched" "Detected in many" 6 "Epicardial cells: 577.6" "Cell type enhanced" "Detected in all" "LAMP5-LHX6 and Chandelier: 30.8" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 12.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 11.1;testis cancer: 9.4" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Lung - Smooth muscle cells, Minor Salivary Gland - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA040606 Uncertain Supported "Plasma membrane" "Secreted to blood" "No annotated function" NA NA 1890000 600000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 48: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 1 "Plasma membrane" "HPA040606: " "unprognostic (4.59e-2)" "unprognostic (6.40e-2)" "unprognostic (2.09e-1)" "unprognostic (1.27e-1)" "unprognostic (2.40e-1)" "unprognostic (2.79e-1)" "unprognostic (1.11e-2)" "unprognostic (1.71e-1)" "unprognostic (2.09e-2)" "unprognostic (2.64e-1)" "unprognostic (2.12e-2)" "unprognostic (2.38e-1)" "unprognostic (4.06e-2)" "unprognostic (1.52e-1)" "unprognostic (2.17e-1)" "unprognostic (1.00e-1)" "unprognostic (3.08e-1)" "unprognostic (1.91e-1)" "unprognostic (5.48e-2)" "unprognostic (6.50e-2)" "unprognostic (2.06e-1)" "potential prognostic unfavorable (7.73e-5)" "unprognostic (9.60e-2)" SCX "bHLHa41, bHLHa48, SCXA, SCXB" ENSG00000260428 "Scleraxis bHLH transcription factor" Q7RTU7 8 144266453-144268481 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.7;thyroid gland: 32.2" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 217.8;Gonadotrophs: 33.4;Innate lymphoid cells: 45.0;Smooth muscle cells: 69.3" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Ovary Serous Cystadenocarcinoma (TCGA): 44.5;Thyroid Carcinoma (TCGA): 52.4;Uterine Corpus Endometrial Carcinoma (TCGA): 16.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 10.7" "Low region specificity" "Detected in some" HPA043183 Uncertain NA NA "Cluster 24: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 2 "HPA043183: " "unprognostic (5.68e-2)" "unprognostic (1.05e-1)" "unprognostic (1.47e-2)" "unprognostic (9.30e-2)" "unprognostic (1.94e-1)" "potential prognostic unfavorable (3.33e-4)" "unprognostic (1.06e-1)" "unprognostic (9.53e-2)" "unprognostic (4.60e-1)" "unprognostic (3.60e-1)" "unprognostic (6.58e-2)" "unprognostic (9.77e-2)" "unprognostic (1.47e-1)" "unprognostic (1.08e-2)" "unprognostic (1.03e-2)" "unprognostic (1.10e-1)" "unprognostic (1.85e-1)" "unprognostic (3.62e-2)" "unprognostic (9.92e-2)" "unprognostic (6.96e-2)" "unprognostic (2.49e-1)" "unprognostic (6.49e-2)" "unprognostic (4.21e-1)" SCYGR1 KRTAP28-1 ENSG00000284629 "Small cysteine and glycine repeat containing 1" A0A286YEY9 2 227387683-227387949 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 11: White matter - Signal transduction" "Cluster 71: Lymphoma - Inflammatory response" SCYGR10 "KRTAP28-10, KRTAP28p2" ENSG00000284622 "Small cysteine and glycine repeat containing 10 (gene/pseudogene)" A0A286YEX9 2 227608784-227609101 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Skin - Inner root sheath cells, Testis - Late spermatids" NA NA "Cluster 32: Cerebral cortex - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" SCYGR2 KRTAP28-2 ENSG00000284643 "Small cysteine and glycine repeat containing 2" A0A286YFB4 2 227598893-227599255 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 16 "skin 1: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Skin - Inner root sheath cells" NA NA "Cluster 9: Skin - Hair follicle development" SCYGR3 KRTAP28-3 ENSG00000284704 "Small cysteine and glycine repeat containing 3" A0A286YF60 2 227614538-227614840 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 23 "skin 1: 2.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Skin - Inner root sheath cells" "Not detected" "Not detected" NA NA "Cluster 9: Skin - Hair follicle development" SCYGR4 KRTAP28-4 ENSG00000284631 "Small cysteine and glycine repeat containing 4" A0A286YEV6 2 227617498-227617815 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "placenta: 8.0" "Cell type enriched" "Detected in single" 9 "Platelets: 7.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Kidney Chromophobe (TCGA): 2.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 13 "Sarcoma: 1.2" "Skin - Hair cortex cells, Skin - Inner root sheath cells, Testis - Late spermatids" "Not detected" "Not detected" NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 47: Endothelial cells - Vasculature" "Cluster 66: Non-specific - Mitochondria" "Cluster 109: Neurons - Neuronal signaling" "unprognostic (5.85e-2)" "unprognostic (2.92e-2)" SCYGR5 KRTAP28-5 ENSG00000284667 "Small cysteine and glycine repeat containing 5" A0A286YF46 2 227666804-227667061 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebral cortex: 2.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 32: Cerebral cortex - Mixed function" "Cluster 109: Neurons - Neuronal signaling" SCYGR6 KRTAP28-6 ENSG00000284725 "Small cysteine and glycine repeat containing 6" A0A286YF77 2 227724440-227724757 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 39 "skin 1: 3.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Skin - Inner root sheath cells" "Not detected" "Not detected" NA NA "Cluster 9: Skin - Hair follicle development" SCYGR7 KRTAP28-7 ENSG00000284718 "Small cysteine and glycine repeat containing 7" A0A286YF01 2 227728335-227728625 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 38 "skin 1: 3.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Skin - Inner root sheath cells" NA NA "Cluster 9: Skin - Hair follicle development" SCYGR8 KRTAP28-8 ENSG00000284635 "Small cysteine and glycine repeat containing 8" A0A286YFG1 2 227745894-227746220 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 31 "skin 1: 3.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Skin - Inner root sheath cells" "Not detected" "Not detected" NA NA "Cluster 9: Skin - Hair follicle development" SCYL1 "GKLP, HT019, MGC78454, NKTL, NTKL, P105, TAPK, TEIF, TRAP" ENSG00000142186 "SCY1 like pseudokinase 1" Q96KG9 11 65525077-65538704 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "ER-Golgi transport, Transcription, Transcription regulation, Transport" "Activator, DNA-binding" "Intellectual disability, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 196.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015015 Supported Cytosol NA NA 4100 "Cluster 7: Non-specific - Innate immune response" "Cluster 70: Non-specific - Protein processing" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 40 Cytosol "HPA015015: " "unprognostic (3.62e-2)" "unprognostic (1.46e-2)" "unprognostic (1.27e-1)" "unprognostic (4.74e-2)" "unprognostic (2.34e-1)" "potential prognostic unfavorable (7.26e-5)" "unprognostic (3.56e-2)" "unprognostic (9.13e-2)" "unprognostic (5.58e-2)" "unprognostic (6.31e-3)" "unprognostic (2.28e-2)" "unprognostic (3.26e-1)" "unprognostic (2.58e-2)" "unprognostic (1.30e-2)" "unprognostic (5.17e-2)" "unprognostic (1.10e-1)" "potential prognostic unfavorable (2.96e-5)" "unprognostic (9.21e-2)" "unprognostic (2.67e-1)" "unprognostic (1.69e-1)" "unprognostic (1.04e-1)" "unprognostic (2.48e-1)" "unprognostic (2.01e-1)" "unprognostic (3.09e-1)" "unprognostic (1.16e-1)" "unprognostic (1.07e-1)" "unprognostic (7.48e-2)" "unprognostic (3.02e-1)" "unprognostic (1.47e-1)" "unprognostic (7.30e-2)" "unprognostic (5.04e-2)" SCYL2 "CVAK104, KIAA1360" ENSG00000136021 "SCY1 like pseudokinase 2" Q6P3W7 12 100267140-100341715 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021050 Approved NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 31: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 16 "HPA021050: " "unprognostic (1.69e-1)" "unprognostic (9.31e-3)" "unprognostic (5.02e-1)" "unprognostic (7.98e-2)" "unprognostic (8.43e-2)" "unprognostic (1.08e-1)" "unprognostic (1.66e-1)" "unprognostic (7.18e-2)" "unprognostic (1.76e-1)" "unprognostic (3.46e-2)" "unprognostic (3.05e-3)" "unprognostic (1.46e-1)" "unprognostic (1.20e-1)" "unprognostic (1.12e-1)" "unprognostic (2.40e-1)" "unprognostic (1.49e-1)" "unprognostic (1.16e-1)" "unprognostic (4.33e-2)" "unprognostic (1.63e-2)" "unprognostic (1.37e-1)" "potential prognostic unfavorable (7.27e-5)" "potential prognostic unfavorable (4.65e-4)" "unprognostic (5.61e-2)" "unprognostic (3.70e-2)" "unprognostic (2.68e-1)" "unprognostic (2.20e-1)" "unprognostic (1.06e-1)" "unprognostic (9.64e-2)" "unprognostic (5.02e-1)" "unprognostic (1.28e-1)" "unprognostic (1.14e-1)" SCYL3 "PACE-1, PACE1" ENSG00000000457 "SCY1 like pseudokinase 3" Q8IZE3 1 169849631-169894267 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005624, HPA072383" Approved Supported "Golgi apparatus,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 45: Non-specific - Nuclear processes" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 23 "Golgi apparatus, Cytosol" "HPA005624: , HPA072383: " "unprognostic (2.62e-1)" "unprognostic (2.93e-1)" "unprognostic (2.67e-1)" "unprognostic (2.54e-2)" "unprognostic (2.55e-1)" "unprognostic (1.48e-1)" "unprognostic (4.08e-2)" "unprognostic (2.65e-2)" "unprognostic (1.08e-2)" "unprognostic (1.11e-2)" "unprognostic (2.86e-2)" "unprognostic (3.00e-2)" "unprognostic (2.76e-1)" "unprognostic (1.49e-1)" "unprognostic (6.18e-2)" "unprognostic (2.46e-1)" "unprognostic (7.13e-2)" "unprognostic (2.32e-1)" "unprognostic (1.08e-1)" "unprognostic (4.51e-1)" "unprognostic (3.58e-2)" "unprognostic (8.60e-2)" "unprognostic (2.15e-1)" "unprognostic (3.23e-1)" "unprognostic (2.05e-1)" "unprognostic (1.30e-1)" "unprognostic (1.40e-1)" "unprognostic (9.98e-2)" "unprognostic (1.70e-1)" "unprognostic (1.50e-1)" "unprognostic (7.05e-2)" SDAD1 FLJ10498 ENSG00000198301 "SDA1 domain containing 1" Q9NVU7 4 75940950-75990962 "Essential proteins, Human disease related genes, Predicted intracellular proteins" "Protein transport, Ribosome biogenesis, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035949 Uncertain Approved Nucleoplasm,Nucleoli NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 17: Non-specific - RNA processing" 40 "Nucleoplasm, Nucleoli" "HPA035949: " "unprognostic (1.99e-1)" "unprognostic (5.21e-3)" "unprognostic (2.64e-1)" "unprognostic (5.34e-2)" "unprognostic (2.16e-2)" "unprognostic (5.27e-3)" "unprognostic (1.43e-1)" "potential prognostic unfavorable (3.46e-4)" "unprognostic (1.80e-1)" "potential prognostic unfavorable (1.10e-4)" "potential prognostic favorable (3.87e-4)" "unprognostic (7.69e-2)" "unprognostic (8.91e-2)" "potential prognostic unfavorable (2.50e-5)" "unprognostic (4.12e-2)" "unprognostic (6.24e-2)" "unprognostic (2.96e-3)" "unprognostic (1.30e-1)" "unprognostic (9.47e-3)" "unprognostic (1.69e-2)" "unprognostic (2.39e-1)" "unprognostic (2.78e-2)" "unprognostic (8.20e-2)" "unprognostic (4.74e-2)" "unprognostic (6.25e-2)" "unprognostic (3.07e-1)" "unprognostic (3.50e-1)" "unprognostic (1.25e-1)" "unprognostic (3.25e-1)" "unprognostic (1.70e-2)" "unprognostic (8.57e-2)" SDC1 "CD138, SDC, SYND1, syndecan" ENSG00000115884 "Syndecan 1" P18827 2 20200797-20225433 "Cancer-related genes, CD markers, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 467.3;liver: 471.7;skin 1: 422.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 303.8;Esophageal apical cells: 1998.8;Esophageal basal cells: 407.2;Esophageal suprabasal cells: 1146.5;Hepatocytes: 682.2;Ocular epithelial cells: 869.6;Prostatic hillock cells: 483.8;Suprabasal keratinocytes: 424.4;Syncytiotrophoblasts: 467.4;Urothelial cells: 638.0" "Cell type enhanced" "Detected in some" "ependymal cell: 3.8;thalamic excitatory: 2.1" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "midbrain: 36.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 564.7" "Breast - Breast myoepithelial cells, Colon - Colon enterocytes, Skin - Keratinocyte (other), Spleen - Plasma cells, Stomach - Gastric mucous cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB002424, HPA006185, HPA067477" Enhanced Approved "Focal adhesion sites" "Secreted to blood" "No annotated function" NA NA 63100000 4300000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 100: Stratified epithelial cells - Barrier functions" 18 "Focal adhesion sites" "CAB002424: , HPA006185: , HPA067477: " "unprognostic (3.16e-1)" "potential prognostic unfavorable (7.54e-5)" "unprognostic (5.32e-2)" "unprognostic (2.43e-3)" "unprognostic (1.56e-1)" "unprognostic (1.50e-2)" "unprognostic (3.01e-3)" "unprognostic (1.03e-1)" "unprognostic (3.24e-2)" "unprognostic (4.12e-2)" "unprognostic (1.70e-2)" "potential prognostic unfavorable (9.01e-4)" "unprognostic (1.07e-1)" "unprognostic (8.20e-2)" "unprognostic (5.48e-2)" "unprognostic (6.85e-2)" "unprognostic (4.83e-2)" "unprognostic (1.26e-2)" "unprognostic (1.39e-1)" "unprognostic (2.18e-2)" "unprognostic (5.42e-2)" "potential prognostic unfavorable (4.54e-4)" "unprognostic (4.34e-1)" "unprognostic (3.20e-1)" "unprognostic (9.15e-2)" "unprognostic (8.17e-2)" "unprognostic (3.00e-2)" "unprognostic (1.28e-2)" "unprognostic (2.82e-1)" "unprognostic (2.81e-1)" "unprognostic (1.01e-1)" SDC2 "CD362, fibroglycan, HSPG, HSPG1, SYND2" ENSG00000169439 "Syndecan 2" P34741 8 96493813-96611790 "CD markers, Predicted membrane proteins" "Differentiation, Neurogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 430.0;thyroid gland: 397.8" "Cell type enhanced" "Detected in many" "Breast lactating cells: 359.1;Decidual stromal cells: 309.6;Fibro-adipogenic progenitors: 306.5;Gonadotrophs: 295.3;Hepatocytes: 327.5;Pituicytes/FSCs: 282.3;Pituitary stem cells: 272.7" "Cell type enhanced" "Detected in all" "Bergmann glia: 209.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "neutrophil: 13.7" "Lineage enriched" "Detected in many" 7 "granulocytes: 13.7" "Low cancer specificity" "Detected in many" "Colon - Fibroblasts, Liver - Hepatocytes, Prostate - Smooth muscle cells, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025123, HPA068532, HPA074427" Uncertain Enhanced "Plasma membrane" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 21: Non-specific - Metabolism" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 55 "Plasma membrane" "CAB025123: , HPA068532: , HPA074427: " "unprognostic (6.47e-3)" "unprognostic (2.22e-1)" "unprognostic (2.37e-3)" "unprognostic (1.43e-2)" "unprognostic (3.00e-2)" "unprognostic (2.01e-1)" "unprognostic (5.02e-3)" "potential prognostic unfavorable (8.09e-4)" "unprognostic (3.09e-2)" "unprognostic (5.69e-3)" "potential prognostic favorable (1.36e-6)" "unprognostic (2.12e-2)" "unprognostic (2.54e-1)" "unprognostic (1.36e-1)" "unprognostic (2.25e-3)" "unprognostic (1.52e-1)" "unprognostic (7.45e-2)" "unprognostic (1.43e-2)" "unprognostic (6.05e-3)" "unprognostic (8.86e-2)" "unprognostic (2.07e-2)" "unprognostic (9.98e-2)" "unprognostic (5.76e-2)" "unprognostic (7.68e-2)" "unprognostic (1.01e-1)" "unprognostic (7.51e-2)" "unprognostic (1.81e-2)" "unprognostic (1.14e-3)" "unprognostic (2.09e-1)" "unprognostic (1.42e-2)" "unprognostic (7.57e-2)" SDC3 "N-syndecan, SYND3" ENSG00000162512 "Syndecan 3" O75056 1 30869466-30908758 "Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 129.1" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 102.3;Decidual stromal cells: 95.0;Kupffer cells: 597.5;Late spermatids: 153.5;Oligodendrocyte progenitor cells: 195.0" "Cell type enhanced" "Detected in all" "oligodendrocyte precursor cell: 176.6" "Group enriched" "Detected in all" 5 "Glioblastoma Multiforme (TCGA): 240.4;Skin Cutaneous Melanoma (TCGA): 236.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in all" "skin cancer: 203.7" "Colon - Smooth muscle cells, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017087, CAB025786, HPA048085" Approved Approved Nucleoplasm,Mitochondria Yes No "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 73: Brain - Neuronal signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 5 Mitochondria Nucleoplasm "CAB025786: , HPA017087: , HPA048085: " "unprognostic (2.01e-2)" "unprognostic (5.73e-3)" "unprognostic (1.86e-2)" "unprognostic (8.99e-2)" "unprognostic (1.12e-1)" "unprognostic (2.30e-1)" "unprognostic (1.10e-1)" "unprognostic (1.77e-2)" "unprognostic (1.95e-1)" "unprognostic (3.41e-2)" "unprognostic (1.96e-2)" "unprognostic (3.24e-1)" "unprognostic (3.65e-2)" "unprognostic (1.45e-2)" "unprognostic (1.57e-1)" "unprognostic (4.89e-2)" "unprognostic (4.01e-2)" "unprognostic (1.15e-1)" "unprognostic (5.64e-1)" "unprognostic (5.06e-3)" "unprognostic (4.73e-2)" "unprognostic (1.76e-1)" "unprognostic (3.41e-2)" "unprognostic (1.50e-2)" "unprognostic (5.04e-2)" "unprognostic (8.75e-3)" "unprognostic (1.86e-2)" "unprognostic (8.98e-3)" "unprognostic (1.69e-1)" "unprognostic (3.54e-2)" "unprognostic (1.26e-1)" SDC4 "amphiglycan, ryudocan, SYND4" ENSG00000124145 "Syndecan 4" P31431 20 45325288-45348424 "Cancer-related genes, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 383.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 877.5;Epididymal efferent duct ciliated cells: 541.4;Transitional alveolar cells: 573.0" "Cell type enriched" "Detected in many" 4 "astrocyte: 253.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Spleen - Fibroblasts_2, Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005716, CAB013240" Enhanced Approved "Golgi apparatus,Plasma membrane" "Secreted to blood" "No annotated function" NA NA 6300000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 81: Alveolar cells - Lung function" 17 "Golgi apparatus" "Plasma membrane" "CAB013240: , HPA005716: " "unprognostic (7.07e-2)" "unprognostic (1.61e-1)" "unprognostic (3.16e-2)" "unprognostic (7.62e-2)" "unprognostic (9.65e-2)" "unprognostic (3.34e-3)" "unprognostic (5.44e-2)" "potential prognostic unfavorable (6.81e-4)" "unprognostic (2.88e-2)" "unprognostic (1.09e-1)" "unprognostic (2.39e-2)" "unprognostic (3.98e-2)" "unprognostic (1.04e-2)" "unprognostic (2.08e-1)" "unprognostic (1.07e-1)" "unprognostic (2.19e-1)" "unprognostic (4.84e-3)" "unprognostic (4.95e-3)" "unprognostic (1.67e-2)" "unprognostic (5.18e-3)" "unprognostic (1.28e-1)" "potential prognostic unfavorable (3.08e-4)" "unprognostic (4.05e-1)" "unprognostic (3.59e-1)" "unprognostic (6.40e-2)" "unprognostic (7.67e-3)" "unprognostic (8.67e-2)" "unprognostic (1.94e-1)" "unprognostic (5.28e-2)" "unprognostic (3.34e-3)" "unprognostic (1.22e-2)" SDCBP "MDA-9, SYCL" ENSG00000137575 "Syndecan binding protein" O00560 8 58552924-58582859 "Plasma proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 1136.8;Hofbauer cells: 1104.7;Melanocytes: 1317.4;monocytes: 926.0;Neutrophils: 3303.2" "Cell type enhanced" "Detected in all" "endothelial cell: 290.6" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 775.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1915.9" "Group enriched" "Detected in all" 5 "granulocytes: 1915.9;monocytes: 563.2" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012245, HPA023840" Approved Supported "Nucleoplasm,Nuclear membrane,Cytosol" "Intracellular and membrane" "No annotated function" NA NA 720000 "Cluster 21: Neutrophils - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 21: Non-specific - Metabolism" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 274 "Nucleoplasm, Cytosol" "Nuclear membrane" "CAB012245: , HPA023840: " "unprognostic (1.25e-1)" "unprognostic (8.79e-2)" "unprognostic (7.01e-3)" "unprognostic (7.04e-2)" "unprognostic (9.93e-2)" "unprognostic (1.11e-1)" "unprognostic (5.86e-2)" "potential prognostic unfavorable (1.62e-4)" "unprognostic (1.09e-2)" "unprognostic (8.08e-2)" "potential prognostic favorable (7.17e-5)" "unprognostic (2.77e-2)" "unprognostic (5.37e-2)" "unprognostic (2.71e-1)" "unprognostic (1.98e-1)" "unprognostic (9.48e-3)" "unprognostic (6.82e-2)" "unprognostic (1.33e-3)" "unprognostic (4.12e-2)" "unprognostic (1.36e-1)" "unprognostic (8.50e-3)" "unprognostic (2.88e-2)" "unprognostic (1.72e-1)" "unprognostic (3.23e-1)" "unprognostic (7.11e-2)" "unprognostic (7.43e-2)" "unprognostic (7.96e-2)" "unprognostic (4.95e-2)" "unprognostic (1.10e-1)" "unprognostic (2.45e-2)" "unprognostic (2.97e-2)" SDCBP2 "SITAC18, ST-2" ENSG00000125775 "Syndecan binding protein 2" Q9H190 20 1309909-1329139 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 140.3;intestine: 128.8;stomach 1: 96.0" "Cell type enhanced" "Detected in many" "Colonocytes: 835.1;Enterocytes: 536.3;Esophageal apical cells: 1781.9;Esophageal suprabasal cells: 365.7;Foveolar cells: 340.7;Pancreatic acinar cells: 210.0;Urothelial cells: 214.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Gastric cancer: 28.9" "Colon - Colon enterocytes, Prostate - Urothelial cells, Skin - Keratinocyte (granular), Stomach - Gastric mucous cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA005804, HPA064490" Enhanced Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 17: Intestine - Digestion" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 51 Nucleoplasm "Golgi apparatus, Cytosol" "HPA005804: , HPA064490: " "unprognostic (7.32e-2)" "unprognostic (1.13e-2)" "unprognostic (5.08e-2)" "unprognostic (2.42e-1)" "unprognostic (2.07e-1)" "unprognostic (4.03e-2)" "unprognostic (1.14e-1)" "unprognostic (3.11e-1)" "unprognostic (4.21e-2)" "unprognostic (2.88e-2)" "validated prognostic favorable (9.36e-5)" "validated prognostic favorable (1.98e-4)" "unprognostic (3.26e-1)" "unprognostic (3.78e-2)" "unprognostic (2.28e-1)" "unprognostic (1.23e-3)" "unprognostic (3.85e-1)" "unprognostic (4.85e-2)" "unprognostic (8.61e-2)" "unprognostic (2.83e-2)" "unprognostic (1.17e-1)" "potential prognostic unfavorable (5.00e-4)" "unprognostic (7.31e-2)" "unprognostic (1.32e-1)" "unprognostic (6.35e-2)" "unprognostic (6.72e-3)" "unprognostic (7.22e-2)" "unprognostic (1.85e-1)" "unprognostic (2.01e-1)" "unprognostic (1.74e-2)" "unprognostic (2.79e-2)" SDCCAG8 "BBS16, CCCAP, NPHP10, NY-CO-8, SLSN7" ENSG00000054282 "SHH signaling and ciliogenesis regulator SDCCAG8" Q86SQ7 1 243256034-243500091 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Bardet-Biedl syndrome, Ciliopathy, Leber congenital amaurosis, Nephronophthisis, Obesity, Senior-Loken syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 262.4;Bergmann glia: 244.4;Brain excitatory neurons: 190.5;Brain inhibitory neurons: 189.7;Choroid plexus epithelial cells: 363.4;Distal convoluted tubule cells: 260.4;Ependymal cells: 299.5;Loop of henle epithelial cells: 204.3;Microglia: 729.4;Oligodendrocyte progenitor cells: 252.7;Oligodendrocytes: 399.9;Podocytes: 192.0;Proximal tubule cells: 189.3;Renal collecting duct intercalated cells: 219.5;Renal collecting duct principal cells: 232.7;Renal connecting tubule cells: 231.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025737, HPA044477, HPA072495" Approved Supported "Primary cilium,Centrosome,Basal body" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 64: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 6 "Centrosome, Basal body" "Primary cilium" "HPA025737: , HPA044477: , HPA072495: " "unprognostic (3.50e-3)" "unprognostic (2.48e-1)" "unprognostic (8.36e-2)" "unprognostic (4.50e-2)" "unprognostic (7.77e-2)" "unprognostic (6.15e-2)" "unprognostic (2.42e-1)" "unprognostic (4.68e-2)" "unprognostic (1.69e-2)" "unprognostic (2.75e-2)" "unprognostic (2.23e-2)" "unprognostic (1.49e-1)" "unprognostic (1.17e-1)" "unprognostic (1.11e-1)" "unprognostic (4.73e-1)" "unprognostic (3.61e-1)" "unprognostic (6.86e-2)" "unprognostic (2.75e-2)" "unprognostic (3.02e-2)" "unprognostic (1.24e-1)" "unprognostic (1.11e-1)" "unprognostic (8.03e-2)" "unprognostic (9.41e-3)" "unprognostic (1.11e-1)" "unprognostic (1.37e-1)" "unprognostic (7.65e-2)" "unprognostic (1.68e-1)" "unprognostic (3.13e-1)" "unprognostic (1.83e-1)" "unprognostic (6.97e-3)" "unprognostic (4.87e-2)" SDE2 "C1orf55, FLJ35382" ENSG00000143751 "SDE2 telomere maintenance homolog" Q6IQ49 1 225982702-225999343 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA replication, Mitosis, mRNA processing, mRNA splicing, Ribosome biogenesis" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 82.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028467, HPA031255, HPA031256" Approved Supported "Nuclear speckles,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 17: Non-specific - RNA processing" 1 "Nuclear speckles" "Golgi apparatus, Plasma membrane, Cytosol" "HPA028467: , HPA031255: , HPA031256: " "unprognostic (4.85e-1)" "unprognostic (7.20e-3)" "unprognostic (1.26e-1)" "unprognostic (9.84e-2)" "unprognostic (7.92e-2)" "unprognostic (1.87e-1)" "unprognostic (1.31e-1)" "unprognostic (6.21e-2)" "unprognostic (8.90e-2)" "potential prognostic favorable (1.57e-5)" "unprognostic (6.24e-2)" "unprognostic (1.55e-1)" "unprognostic (8.26e-2)" "unprognostic (1.01e-1)" "unprognostic (1.47e-2)" "unprognostic (9.23e-2)" "unprognostic (7.38e-2)" "unprognostic (1.73e-1)" "unprognostic (3.91e-3)" "unprognostic (1.47e-2)" "unprognostic (1.06e-1)" "unprognostic (1.39e-1)" "unprognostic (1.99e-1)" "unprognostic (1.06e-1)" "unprognostic (9.29e-2)" "unprognostic (2.67e-1)" "unprognostic (1.47e-1)" "unprognostic (9.99e-3)" "unprognostic (3.52e-1)" SDF2 ENSG00000132581 "Stromal cell derived factor 2" Q99470 17 28648346-28662189 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 227.4;Syncytiotrophoblasts: 272.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042799 Approved Vesicles "Intracellular and membrane" "No annotated function" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 27: Breast cancer - Unknown function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 10 Vesicles "HPA042799: " "unprognostic (7.78e-2)" "unprognostic (2.02e-2)" "unprognostic (2.48e-2)" "unprognostic (5.24e-2)" "unprognostic (1.88e-1)" "unprognostic (1.75e-1)" "unprognostic (2.09e-1)" "unprognostic (9.82e-2)" "unprognostic (2.12e-3)" "unprognostic (3.00e-1)" "potential prognostic favorable (1.91e-4)" "unprognostic (1.94e-1)" "unprognostic (2.21e-1)" "validated prognostic unfavorable (5.36e-4)" "validated prognostic unfavorable (5.88e-4)" "unprognostic (2.29e-1)" "unprognostic (2.36e-2)" "unprognostic (4.13e-3)" "unprognostic (8.47e-2)" "unprognostic (4.02e-3)" "unprognostic (6.55e-2)" "unprognostic (2.49e-1)" "unprognostic (3.79e-1)" "unprognostic (4.90e-2)" "unprognostic (6.22e-1)" "unprognostic (3.80e-2)" "unprognostic (6.80e-2)" "unprognostic (2.15e-3)" "unprognostic (3.18e-1)" "unprognostic (1.18e-1)" "unprognostic (1.16e-1)" SDF2L1 "AP000553.C22.4, OTTHUMT00000075032" ENSG00000128228 "Stromal cell derived factor 2 like 1" Q9HCN8 22 21642302-21644299 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 167.9" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 359.2;Epididymal principal cells: 1250.2;Extravillous trophoblasts: 454.8;Hepatocytes: 324.6;Plasma cells: 761.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005638 Approved "Intracellular and membrane" "No annotated function" NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 70: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 8: Non-specific - Secretory pathway" 148 "HPA005638: " "unprognostic (1.30e-1)" "unprognostic (1.48e-1)" "unprognostic (8.14e-2)" "unprognostic (6.26e-2)" "unprognostic (4.63e-2)" "unprognostic (2.20e-2)" "potential prognostic unfavorable (8.26e-4)" "unprognostic (1.99e-1)" "unprognostic (5.10e-2)" "unprognostic (8.90e-2)" "unprognostic (2.87e-2)" "unprognostic (5.02e-2)" "unprognostic (1.16e-2)" "unprognostic (7.83e-2)" "unprognostic (9.55e-3)" "unprognostic (2.57e-1)" "unprognostic (1.22e-1)" "unprognostic (2.04e-1)" "unprognostic (1.71e-1)" "unprognostic (2.16e-3)" "unprognostic (2.39e-1)" "unprognostic (1.59e-2)" "unprognostic (4.14e-2)" "unprognostic (2.12e-1)" "unprognostic (1.18e-1)" "unprognostic (1.58e-1)" "unprognostic (7.66e-2)" "unprognostic (1.67e-1)" "unprognostic (3.95e-2)" "unprognostic (2.42e-1)" "unprognostic (9.67e-2)" SDF4 Cab45 ENSG00000078808 "Stromal cell derived factor 4" 1 1216931-1232031 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Enterocytes: 302.8;Extravillous trophoblasts: 382.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011249, HPA011895, CAB015227" Supported Supported Supported "Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 37: Non-specific - mRNA processing" "Cluster 8: Non-specific - Secretory pathway" 6 "Golgi apparatus" "CAB015227: , HPA011249: , HPA011895: " "unprognostic (1.37e-1)" "unprognostic (6.01e-2)" "unprognostic (4.77e-2)" "potential prognostic unfavorable (4.18e-4)" "unprognostic (3.87e-3)" "unprognostic (2.94e-1)" "unprognostic (3.86e-2)" "unprognostic (4.56e-2)" "unprognostic (1.50e-1)" "unprognostic (3.57e-3)" "potential prognostic favorable (7.16e-4)" "unprognostic (1.24e-1)" "unprognostic (1.47e-1)" "unprognostic (1.98e-3)" "potential prognostic unfavorable (3.81e-5)" "unprognostic (1.74e-1)" "unprognostic (2.75e-2)" "unprognostic (1.63e-1)" "unprognostic (1.84e-1)" "unprognostic (8.58e-2)" "unprognostic (1.29e-1)" "unprognostic (2.34e-1)" "unprognostic (2.91e-1)" "unprognostic (1.76e-1)" "unprognostic (2.41e-2)" "unprognostic (1.10e-1)" "unprognostic (8.96e-2)" "unprognostic (1.18e-1)" "unprognostic (1.34e-1)" "unprognostic (9.55e-2)" "unprognostic (1.26e-1)" SDHA "FP, SDH2, SDHF" ENSG00000073578 "Succinate dehydrogenase complex flavoprotein subunit A" P31040 5 218303-257082 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Electron transport, Transport, Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, Cardiomyopathy, Disease variant, FDA approved drug targets, Leigh syndrome, Neurodegeneration, Primary mitochondrial disease, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 522.4;skeletal muscle: 446.5" "Cell type enhanced" "Detected in many" "Astrocytes: 32.2;Bergmann glia: 35.4;Brain excitatory neurons: 46.0;Brain inhibitory neurons: 39.5;Choroid plexus epithelial cells: 61.8;Distal convoluted tubule cells: 76.1;Ependymal cells: 35.9;Loop of henle epithelial cells: 63.2;Oligodendrocyte progenitor cells: 37.7;Oligodendrocytes: 52.3;Other brain neurons: 36.1;Papillary tip epithelial cells: 34.5;Podocytes: 41.8;Proximal tubule cells: 55.6;Renal collecting duct intercalated cells: 91.3;Renal collecting duct principal cells: 54.1;Renal connecting tubule cells: 75.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034929, HPA041981" Enhanced Supported "Plasma membrane,Mitochondria" No No 230000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 45: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 102: Non-specific - Mixed function" 52 Mitochondria "Plasma membrane" "CAB034929: , HPA041981: " "unprognostic (1.54e-2)" "potential prognostic unfavorable (8.39e-4)" "unprognostic (1.05e-1)" "unprognostic (1.24e-3)" "unprognostic (2.59e-2)" "unprognostic (2.63e-1)" "unprognostic (1.10e-1)" "unprognostic (3.26e-2)" "unprognostic (4.44e-1)" "unprognostic (1.11e-2)" "potential prognostic favorable (5.99e-4)" "unprognostic (1.82e-1)" "potential prognostic favorable (1.56e-4)" "unprognostic (3.64e-2)" "unprognostic (1.24e-1)" "unprognostic (2.35e-2)" "unprognostic (2.44e-2)" "unprognostic (1.76e-1)" "unprognostic (1.12e-1)" "unprognostic (1.23e-1)" "unprognostic (3.13e-2)" "unprognostic (1.64e-1)" "unprognostic (1.68e-1)" "unprognostic (8.02e-2)" "unprognostic (3.00e-1)" "unprognostic (1.87e-2)" "unprognostic (1.93e-1)" "unprognostic (8.31e-2)" "unprognostic (2.58e-1)" "unprognostic (2.89e-1)" "unprognostic (1.91e-1)" SDHAF1 LYRM8 ENSG00000205138 "Succinate dehydrogenase complex assembly factor 1" A6NFY7 19 35995188-35996312 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Chaperone "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064277, HPA074563" Supported Mitochondria NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 64: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 4 Mitochondria "HPA064277: , HPA074563: " "unprognostic (2.85e-3)" "unprognostic (2.33e-1)" "potential prognostic unfavorable (8.89e-5)" "unprognostic (1.86e-1)" "unprognostic (4.81e-2)" "unprognostic (7.68e-2)" "unprognostic (1.80e-1)" "unprognostic (1.74e-1)" "unprognostic (6.76e-2)" "unprognostic (5.41e-2)" "unprognostic (2.30e-3)" "unprognostic (1.39e-1)" "potential prognostic favorable (2.61e-4)" "unprognostic (2.05e-2)" "unprognostic (3.63e-2)" "unprognostic (6.65e-2)" "unprognostic (1.70e-1)" "unprognostic (3.48e-3)" "unprognostic (4.94e-2)" "unprognostic (3.81e-2)" "unprognostic (1.51e-1)" "unprognostic (1.77e-3)" "unprognostic (2.72e-1)" "unprognostic (1.99e-2)" "unprognostic (1.52e-2)" "unprognostic (7.97e-3)" "unprognostic (2.32e-2)" "unprognostic (1.09e-1)" "unprognostic (4.15e-1)" "unprognostic (1.43e-1)" "unprognostic (1.22e-1)" SDHAF2 "C11orf79, FLJ20487, PGL2, SDH5" ENSG00000167985 "Succinate dehydrogenase complex assembly factor 2" Q9NX18 11 61430042-61446733 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" Chaperone "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in some" 4 "Megakaryocytes: 12.4" "Cell type enhanced" "Detected in single" "Bergmann glia: 1.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039464, HPA039732" Supported Approved Nucleoli,Mitochondria,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 24: Non-specific - Unknown function" "Cluster 47: Platelets - Hemostasis" 6 "Mitochondria, Cytosol" Nucleoli "HPA039464: , HPA039732: " "unprognostic (2.10e-3)" "unprognostic (8.05e-2)" "unprognostic (4.33e-2)" "unprognostic (4.31e-1)" "unprognostic (4.07e-2)" "unprognostic (3.06e-2)" "unprognostic (4.74e-2)" "unprognostic (2.62e-3)" "unprognostic (1.14e-1)" "unprognostic (5.95e-3)" "unprognostic (8.78e-2)" "unprognostic (3.77e-2)" "unprognostic (2.43e-2)" "validated prognostic unfavorable (1.15e-4)" "validated prognostic unfavorable (7.62e-4)" "unprognostic (2.76e-3)" "potential prognostic unfavorable (5.25e-4)" "unprognostic (1.82e-1)" "unprognostic (2.99e-1)" "unprognostic (1.05e-2)" "unprognostic (1.78e-1)" "unprognostic (6.05e-2)" "unprognostic (1.53e-2)" "unprognostic (2.24e-1)" "unprognostic (2.05e-1)" "unprognostic (1.96e-1)" "unprognostic (1.22e-1)" "unprognostic (2.57e-1)" "unprognostic (1.79e-1)" "unprognostic (2.78e-1)" "unprognostic (2.97e-1)" SDHAF3 "ACN9, DC11, LYRM10, Sdh7" ENSG00000196636 "Succinate dehydrogenase complex assembly factor 3" Q9NRP4 7 97117698-97181763 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 151.7;Megakaryocytes: 160.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "HPA020515, HPA020523" Approved Approved Mitochondria NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 76: Non-specific - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 5 Mitochondria "HPA020515: , HPA020523: " "unprognostic (1.23e-1)" "unprognostic (2.58e-2)" "unprognostic (2.80e-1)" "unprognostic (6.49e-2)" "unprognostic (4.46e-2)" "unprognostic (4.11e-1)" "unprognostic (3.51e-2)" "unprognostic (2.70e-2)" "unprognostic (1.65e-1)" "unprognostic (1.30e-2)" "unprognostic (3.86e-1)" "unprognostic (3.08e-2)" "unprognostic (4.47e-3)" "unprognostic (2.56e-1)" "unprognostic (3.27e-1)" "unprognostic (1.18e-2)" "unprognostic (1.96e-3)" "unprognostic (1.45e-2)" "unprognostic (2.81e-1)" "unprognostic (6.54e-2)" "unprognostic (6.61e-2)" "unprognostic (1.73e-1)" "potential prognostic favorable (2.71e-4)" "unprognostic (1.19e-1)" "unprognostic (1.88e-2)" "unprognostic (1.75e-1)" "unprognostic (5.35e-2)" "unprognostic (1.02e-1)" "unprognostic (1.51e-1)" SDHAF4 "C6orf57, Sdh8" ENSG00000154079 "Succinate dehydrogenase complex assembly factor 4" Q5VUM1 6 70566917-70589569 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031824 Supported Approved Nucleoplasm,Mitochondria No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 28: Non-specific - Nuclear processes" "Cluster 89: Adipocytes - Lipid metabolism" 4 Mitochondria Nucleoplasm "HPA031824: " "unprognostic (5.34e-2)" "unprognostic (3.36e-3)" "unprognostic (1.04e-1)" "unprognostic (9.94e-2)" "unprognostic (2.31e-2)" "unprognostic (2.94e-1)" "unprognostic (1.33e-1)" "unprognostic (2.60e-1)" "unprognostic (7.63e-3)" "potential prognostic favorable (5.17e-4)" "unprognostic (2.38e-3)" "potential prognostic favorable (1.59e-4)" "unprognostic (8.56e-2)" "unprognostic (1.20e-1)" "unprognostic (1.12e-2)" "unprognostic (3.15e-2)" "unprognostic (2.23e-1)" "unprognostic (2.04e-3)" "unprognostic (2.21e-1)" "unprognostic (4.94e-2)" "unprognostic (5.25e-2)" "unprognostic (1.21e-1)" "unprognostic (1.31e-2)" "unprognostic (4.47e-3)" "unprognostic (7.71e-2)" "unprognostic (5.88e-2)" "unprognostic (8.58e-2)" "unprognostic (1.68e-1)" "unprognostic (3.24e-1)" SDHB "SDH, SDH1" ENSG00000117118 "Succinate dehydrogenase complex iron sulfur subunit B" P21912 1 17018722-17054032 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Electron transport, Host-virus interaction, Transport, Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 460.5;tongue: 542.0" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 348.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Spleen - Macrophages, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002868, CAB009822, CAB068233, CAB068234, CAB068235" Enhanced Supported "Nucleoplasm,Plasma membrane,Mitochondria" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 37: Non-specific - mRNA processing" "Cluster 97: Non-specific - Cellular respiration" 28 Mitochondria "Nucleoplasm, Plasma membrane" "CAB009822: , CAB068233: , CAB068234: , CAB068235: , HPA002868: " "unprognostic (5.47e-2)" "unprognostic (2.03e-1)" "potential prognostic unfavorable (2.39e-4)" "unprognostic (7.63e-2)" "unprognostic (4.57e-3)" "unprognostic (4.21e-1)" "unprognostic (1.70e-1)" "unprognostic (5.12e-2)" "unprognostic (2.36e-3)" "unprognostic (1.20e-3)" "potential prognostic favorable (4.70e-11)" "unprognostic (1.11e-3)" "potential prognostic favorable (2.00e-4)" "unprognostic (1.47e-1)" "unprognostic (1.46e-1)" "unprognostic (1.85e-1)" "unprognostic (1.07e-1)" "unprognostic (2.65e-1)" "unprognostic (2.06e-1)" "unprognostic (5.52e-2)" "unprognostic (4.71e-2)" "unprognostic (2.73e-2)" "unprognostic (1.57e-1)" "unprognostic (1.47e-1)" "unprognostic (1.20e-1)" "unprognostic (2.15e-1)" "unprognostic (3.81e-1)" "unprognostic (5.25e-2)" "unprognostic (2.34e-1)" "unprognostic (3.86e-1)" "unprognostic (3.77e-1)" SDHC "CYB560, cybL, PGL3" ENSG00000143252 "Succinate dehydrogenase complex subunit C" Q99643 1 161314381-161363206 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Electron transport, Transport, Tricarboxylic acid cycle" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 406.5;Parietal cells: 403.1;Syncytiotrophoblasts: 299.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 45: Non-specific - Nuclear processes" "Cluster 97: Non-specific - Cellular respiration" 5 "potential prognostic unfavorable (3.71e-4)" "unprognostic (7.06e-3)" "unprognostic (9.02e-2)" "unprognostic (8.49e-2)" "unprognostic (1.19e-3)" "unprognostic (1.03e-1)" "unprognostic (3.18e-1)" "unprognostic (2.15e-1)" "unprognostic (1.07e-2)" "unprognostic (1.05e-1)" "potential prognostic favorable (1.20e-5)" "unprognostic (5.59e-2)" "unprognostic (6.25e-2)" "unprognostic (2.32e-2)" "unprognostic (1.38e-1)" "unprognostic (2.37e-2)" "unprognostic (1.13e-1)" "unprognostic (2.34e-2)" "unprognostic (7.29e-2)" "unprognostic (2.83e-1)" "unprognostic (2.53e-2)" "unprognostic (1.61e-2)" "unprognostic (5.71e-2)" "unprognostic (4.93e-2)" "unprognostic (3.32e-1)" "unprognostic (1.48e-1)" "unprognostic (3.99e-1)" "unprognostic (1.96e-1)" "unprognostic (2.39e-1)" "unprognostic (2.85e-2)" "unprognostic (2.59e-1)" SDHD "cybS, PGL, PGL1" ENSG00000204370 "Succinate dehydrogenase complex subunit D" O14521 11 112086824-112120016 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Essential proteins, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Electron transport, Transport, Tricarboxylic acid cycle" "Cancer-related genes, Disease variant, FDA approved drug targets, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 17.6" "Cell type enhanced" "Detected in some" "pericyte: 2.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA045727 Approved NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 24: Non-specific - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 4 "HPA045727: " "unprognostic (2.24e-1)" "unprognostic (4.41e-2)" "unprognostic (3.69e-1)" "unprognostic (3.50e-3)" "unprognostic (1.14e-1)" "unprognostic (8.03e-2)" "unprognostic (5.58e-2)" "unprognostic (1.54e-1)" "unprognostic (2.86e-2)" "unprognostic (6.14e-3)" "potential prognostic favorable (3.67e-10)" "unprognostic (9.48e-3)" "unprognostic (5.23e-2)" "unprognostic (2.47e-1)" "unprognostic (8.49e-2)" "unprognostic (8.25e-2)" "unprognostic (1.04e-1)" "unprognostic (9.58e-3)" "unprognostic (1.95e-1)" "unprognostic (1.59e-1)" "unprognostic (1.08e-1)" "potential prognostic unfavorable (6.51e-5)" "unprognostic (3.75e-1)" "unprognostic (9.94e-2)" "unprognostic (1.79e-2)" "unprognostic (2.69e-3)" "unprognostic (2.37e-2)" "unprognostic (2.63e-1)" "unprognostic (1.58e-1)" "unprognostic (2.04e-2)" "unprognostic (2.80e-1)" SDK1 FLJ31425 ENSG00000146555 "Sidekick cell adhesion molecule 1" Q7Z5N4 7 3301252-4269000 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 11.8" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 2278.2;Ependymal cells: 1133.6;Pancreatic islet cells: 1076.1;Pituicytes/FSCs: 2575.6;Respiratory basal cells: 1787.8;Respiratory ciliated cells: 1091.4;Respiratory deuterosomal cells: 1462.7;Respiratory secretory cells: 2023.2" "Cell type enhanced" "Detected in all" "hippocampal CA4: 1871.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Smooth muscle cells, Skin - Fibroblasts_2, Spleen - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA011392 Approved Approved Cytosol NA NA 3500000 "Cluster 70: Non-specific - Protein processing" "Cluster 29: Forebrain - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" Cytosol "HPA011392: " "unprognostic (2.60e-2)" "unprognostic (6.46e-2)" "unprognostic (1.35e-2)" "unprognostic (1.26e-3)" "unprognostic (2.55e-1)" "unprognostic (1.56e-1)" "unprognostic (6.36e-3)" "unprognostic (7.99e-2)" "unprognostic (5.68e-2)" "unprognostic (5.99e-3)" "potential prognostic favorable (5.80e-4)" "unprognostic (7.08e-2)" "unprognostic (1.02e-2)" "unprognostic (5.21e-3)" "potential prognostic favorable (5.28e-4)" "unprognostic (1.33e-1)" "unprognostic (7.02e-3)" "unprognostic (1.86e-1)" "unprognostic (5.00e-1)" "unprognostic (3.21e-3)" "unprognostic (1.31e-2)" "unprognostic (2.81e-1)" "unprognostic (1.58e-3)" "unprognostic (1.02e-1)" "unprognostic (2.72e-2)" "unprognostic (1.61e-1)" "unprognostic (2.33e-1)" "unprognostic (1.53e-1)" SDK2 "FLJ10832, KIAA1514" ENSG00000069188 "Sidekick cell adhesion molecule 2" Q58EX2 17 73334384-73644445 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 5.2;testis: 9.1" "Cell type enhanced" "Detected in many" "Ependymal cells: 156.1;Extravillous trophoblasts: 149.2;Neuroendocrine cells: 102.6;Retinal bipolar cells: 93.1;Retinal horizontal cells: 146.2;Sertoli cells: 221.2;Syncytiotrophoblasts: 86.9;Thymocytes: 103.3" "Cell type enhanced" "Detected in all" "deep-layer corticothalamic and 6b: 217.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 5.7;testis cancer: 6.6" "Adrenal gland - Adrenal medulla cells, Breast - Breast myoepithelial cells, Colon - Enteric glia cells, Liver - Hepatic stellate cells, Minor Salivary Gland - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA 1700000 "Cluster 30: Non-specific - DNA binding" "Cluster 75: Ovary - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" 1 "unprognostic (6.40e-3)" "unprognostic (9.19e-2)" "unprognostic (8.00e-3)" "unprognostic (2.57e-1)" "unprognostic (1.51e-2)" "unprognostic (1.25e-2)" "unprognostic (2.49e-1)" "unprognostic (1.92e-3)" "unprognostic (2.19e-1)" "unprognostic (7.74e-2)" "unprognostic (1.16e-1)" "unprognostic (2.18e-1)" "unprognostic (2.02e-1)" "unprognostic (4.35e-2)" "unprognostic (1.60e-1)" "unprognostic (1.21e-1)" "unprognostic (1.07e-1)" "unprognostic (6.52e-3)" "unprognostic (4.96e-2)" "unprognostic (2.00e-1)" SDR16C5 "EPHD-2, RDH-E2, RDHE2" ENSG00000170786 "Short chain dehydrogenase/reductase family 16C member 5" Q8N3Y7 8 56300005-56320776 "Enzymes, Metabolic proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 38.2;lung: 26.9;skin 1: 47.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 230.7;Alveolar cells type 2: 654.2;Esophageal apical cells: 823.5;Esophageal suprabasal cells: 263.3;Suprabasal keratinocytes: 221.2;Transitional alveolar cells: 168.6" "Cell type enhanced" "Detected in many" "lower rhombic lip: 21.3" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 36.1" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 36 "memory B-cell: 4.7;naive B-cell: 2.3" "Lineage enriched" "Detected in single" 48 "B-cells: 4.7" "Cancer enhanced" "Detected in many" "Bile duct cancer: 15.5" "Breast - Breast glandular cells, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Urothelial cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA025224 Enhanced NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 18 "HPA025224: " "unprognostic (9.79e-2)" "unprognostic (2.32e-1)" "unprognostic (1.37e-1)" "unprognostic (2.64e-1)" "unprognostic (9.32e-2)" "potential prognostic unfavorable (7.13e-4)" "unprognostic (1.28e-3)" "unprognostic (1.08e-1)" "unprognostic (7.14e-2)" "unprognostic (5.50e-2)" "unprognostic (2.04e-1)" "unprognostic (1.19e-3)" "unprognostic (4.43e-1)" "unprognostic (3.96e-1)" "unprognostic (6.64e-3)" "unprognostic (2.45e-1)" "unprognostic (2.19e-1)" SDR39U1 "C14orf124, HCDI" ENSG00000100445 "Short chain dehydrogenase/reductase family 39U member 1" Q9NRG7 14 24439766-24442905 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044294, HPA075356" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 97: Non-specific - Cellular respiration" "Nucleoplasm, Cytosol" "HPA044294: , HPA075356: " "unprognostic (4.05e-2)" "unprognostic (1.33e-2)" "unprognostic (4.38e-2)" "unprognostic (1.09e-1)" "unprognostic (1.11e-1)" "unprognostic (1.94e-1)" "unprognostic (2.34e-1)" "potential prognostic favorable (8.00e-4)" "unprognostic (3.18e-1)" "unprognostic (2.05e-2)" "unprognostic (3.58e-3)" "unprognostic (2.17e-3)" "potential prognostic favorable (4.67e-5)" "unprognostic (1.24e-2)" "unprognostic (3.65e-1)" "unprognostic (3.14e-2)" "unprognostic (1.00e-1)" "unprognostic (1.60e-2)" "unprognostic (1.54e-2)" "potential prognostic favorable (9.65e-4)" "unprognostic (1.30e-3)" "potential prognostic favorable (2.97e-4)" "unprognostic (3.26e-2)" "unprognostic (3.73e-1)" "unprognostic (3.61e-2)" "unprognostic (1.71e-1)" "unprognostic (1.66e-1)" "unprognostic (7.59e-2)" "unprognostic (2.78e-2)" "unprognostic (1.51e-2)" "unprognostic (1.89e-1)" SDR42E1 HSPC105 ENSG00000184860 "Short chain dehydrogenase/reductase family 42E, member 1" Q8WUS8 16 81988855-82011481 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "skin 1: 8.7" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 14.1;Esophageal suprabasal cells: 16.1;Podocytes: 17.3;Suprabasal keratinocytes: 14.9" "Cell type enhanced" "Detected in some" "eccentric medium spiny neuron: 1.8;leukocyte: 2.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 2.3;NK-cells: 2.0;T-cells: 2.2" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014388 Uncertain NA NA "Cluster 24: Non-specific - Transcription" "Cluster 58: Skin - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 26: Keratinocytes - Keratinization" "HPA014388: " "potential prognostic favorable (6.96e-4)" "unprognostic (3.63e-1)" "unprognostic (2.54e-2)" "unprognostic (1.62e-1)" "unprognostic (1.65e-1)" "unprognostic (4.84e-2)" "unprognostic (7.99e-2)" "unprognostic (3.95e-2)" "potential prognostic favorable (6.89e-5)" "unprognostic (8.13e-2)" "unprognostic (7.79e-3)" "potential prognostic favorable (5.59e-4)" "unprognostic (1.86e-2)" "unprognostic (2.18e-1)" "unprognostic (8.66e-2)" "unprognostic (2.52e-1)" "unprognostic (1.79e-1)" "unprognostic (7.25e-2)" "unprognostic (6.75e-2)" "unprognostic (1.94e-1)" "unprognostic (2.57e-2)" "potential prognostic favorable (1.31e-4)" "unprognostic (1.14e-1)" "unprognostic (1.01e-1)" "unprognostic (2.34e-1)" "unprognostic (2.64e-1)" "unprognostic (2.68e-2)" SDR42E2 ENSG00000183921 "Short chain dehydrogenase/reductase family 42E, member 2" A6NKP2 16 22162492-22192208 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "testis: 1.7" "Cell type enriched" "Detected in some" 5 "Ependymal cells: 56.8" "Cell type enriched" "Detected in many" 7 "ependymal cell: 58.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "neutrophil: 5.3" "Lineage enriched" "Detected in single" 6 "granulocytes: 5.3" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 48: Non-specific - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 34: Ciliated cells - Cilia assembly & function" SDR9C7 "RDHS, SDR-O" ENSG00000170426 "Short chain dehydrogenase/reductase family 9C member 7" Q8NEX9 12 56923133-56934408 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 20.7;skin 1: 56.4;vagina: 20.1" "Cell type enhanced" "Detected in some" "Esophageal apical cells: 74.8;Esophageal suprabasal cells: 16.1;Retinal horizontal cells: 4.0;Suprabasal keratinocytes: 20.4" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in some" "Head and Neck Squamous Cell Carcinoma (TCGA): 15.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 58: Skin - Keratinization" "Cluster 53: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 22 "unprognostic (3.97e-2)" "unprognostic (1.65e-1)" "unprognostic (5.30e-2)" "unprognostic (2.16e-2)" "unprognostic (3.43e-1)" "unprognostic (1.53e-1)" SDS SDH ENSG00000135094 "Serine dehydratase" P20132 12 113392445-113426301 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Gluconeogenesis, Lipid metabolism" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 20 "liver: 971.8" "Group enriched" "Detected in some" 4 "Hepatocytes: 480.7;Macrophages: 155.8" "Group enriched" "Detected in some" 15 "astrocyte: 42.6;Bergmann glia: 28.5" "Cancer enriched" "Detected in all" 27 "Liver Hepatocellular Carcinoma (TCGA): 377.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 10 "myeloid DC: 11.6" "Lineage enriched" "Detected in single" 15 "dendritic cells: 11.6" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA039230 Uncertain Approved Mitochondria,Cytosol NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 19: Astrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 3 Cytosol Mitochondria "HPA039230: " "unprognostic (5.94e-2)" "unprognostic (1.45e-2)" "unprognostic (8.22e-2)" "unprognostic (7.36e-3)" "unprognostic (1.67e-2)" "unprognostic (1.75e-1)" "unprognostic (1.85e-3)" "unprognostic (7.53e-2)" "unprognostic (2.53e-2)" "unprognostic (4.36e-1)" "unprognostic (1.00e-1)" "unprognostic (3.59e-1)" "unprognostic (1.45e-2)" "unprognostic (2.59e-2)" "potential prognostic favorable (4.07e-4)" "unprognostic (4.05e-1)" "unprognostic (1.60e-2)" "unprognostic (6.83e-2)" "unprognostic (2.91e-1)" "unprognostic (2.61e-1)" "unprognostic (2.59e-1)" "unprognostic (9.17e-2)" "unprognostic (9.01e-2)" "unprognostic (3.98e-1)" "unprognostic (1.62e-1)" "unprognostic (1.05e-2)" "unprognostic (2.60e-1)" "unprognostic (5.74e-2)" "unprognostic (4.91e-3)" "unprognostic (7.88e-2)" "unprognostic (1.88e-2)" SDSL "cSDH, SDS-RS1" ENSG00000139410 "Serine dehydratase like" Q96GA7 12 113422380-113438276 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Isomerase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 102.4" "Cell type enhanced" "Detected in many" "Colonocytes: 51.0;Enterocytes: 57.7;Epididymal efferent duct absorptive cells: 43.5;Epididymal principal cells: 49.8;Hepatocytes: 122.2;Hofbauer cells: 60.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 8.7;intermediate monocyte: 10.0;myeloid DC: 18.5;plasmacytoid DC: 17.9" "Group enriched" "Detected in many" 6 "dendritic cells: 18.5;monocytes: 10.0" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 77.6" "Adrenal gland - Adrenal cortex cells, Lung - Macrophages, Prostate - Prostate glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA005740 Approved Approved Cytosol NA NA 25000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 27: Breast cancer - Unknown function" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 1 Cytosol "HPA005740: " "unprognostic (6.19e-2)" "unprognostic (2.12e-1)" "unprognostic (2.92e-1)" "unprognostic (1.11e-1)" "unprognostic (2.39e-1)" "unprognostic (1.23e-1)" "unprognostic (2.49e-2)" "unprognostic (2.44e-1)" "unprognostic (5.25e-2)" "potential prognostic unfavorable (8.13e-7)" "unprognostic (1.15e-2)" "unprognostic (1.26e-1)" "unprognostic (2.99e-3)" "unprognostic (8.71e-2)" "unprognostic (4.59e-2)" "unprognostic (7.38e-3)" "unprognostic (1.73e-2)" "unprognostic (5.42e-2)" "unprognostic (6.38e-3)" "unprognostic (6.85e-3)" "unprognostic (9.59e-2)" "unprognostic (1.32e-2)" "unprognostic (9.98e-2)" "unprognostic (2.65e-1)" "unprognostic (5.06e-2)" "unprognostic (7.75e-2)" "unprognostic (3.24e-2)" "unprognostic (1.33e-2)" "unprognostic (1.30e-2)" "unprognostic (1.01e-1)" "unprognostic (1.33e-3)" SEBOX "OG9, OG9X" ENSG00000274529 "SEBOX homeobox" Q9HB31 17 28363506-28365199 "Predicted intracellular proteins" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "liver: 1.1" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 2.1;Early spermatids: 6.2;Late spermatids: 8.1;Retinal horizontal cells: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebellum: 36.1" "Not detected" "Not detected" HPA045689 Uncertain NA NA "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 15: Non-specific - Transcription" "Cluster 56: Non-specific - Sensory perception" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" "HPA045689: " "unprognostic (4.82e-2)" "unprognostic (1.45e-1)" SEC11A "SEC11L1, sid2895, SPC18, SPCS4A" ENSG00000140612 "SEC11 homolog A, signal peptidase complex subunit" P67812 15 84669538-84716460 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 864.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047533 Approved "Nuclear membrane,Golgi apparatus" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 75: Ovary - Mixed function" "Cluster 12: Non-specific - Vasculature" "Cluster 58: Non-specific - Nuclear processes" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 34 "Nuclear membrane" "Golgi apparatus" "HPA047533: " "unprognostic (2.82e-1)" "unprognostic (1.83e-1)" "unprognostic (9.62e-2)" "unprognostic (1.36e-2)" "unprognostic (5.35e-2)" "unprognostic (3.64e-2)" "unprognostic (3.09e-1)" "unprognostic (1.49e-1)" "potential prognostic unfavorable (2.14e-5)" "unprognostic (1.25e-1)" "potential prognostic favorable (4.01e-7)" "unprognostic (1.77e-2)" "unprognostic (1.86e-1)" "unprognostic (3.51e-2)" "potential prognostic unfavorable (4.68e-7)" "unprognostic (5.63e-2)" "unprognostic (3.56e-2)" "unprognostic (8.45e-2)" "unprognostic (1.69e-1)" "unprognostic (3.25e-2)" "unprognostic (1.15e-1)" "unprognostic (3.61e-3)" "unprognostic (1.39e-2)" "unprognostic (1.98e-2)" "unprognostic (2.61e-1)" "unprognostic (1.94e-2)" "unprognostic (5.22e-2)" "unprognostic (6.17e-2)" "unprognostic (2.57e-1)" "unprognostic (1.55e-1)" "unprognostic (8.51e-3)" SEC11C "SEC11L3, SPC21, SPCS4C" ENSG00000166562 "SEC11 homolog C, signal peptidase complex subunit" Q9BY50 18 59139866-59158832 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epididymal principal cells: 989.1;Pancreatic islet cells: 472.0;Plasma cells: 1835.8;Prostatic glandular cells: 792.4;Respiratory ionocytes: 807.7;Salivary acinar cells: 569.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 521.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Myeloma: 868.3" "Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026816, HPA047533" Approved Approved "Nuclear membrane,Golgi apparatus" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 70: Non-specific - Protein processing" "Cluster 27: Non-specific - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 44: Plasma cells - Antibody production & secretion" 25 "Nuclear membrane" "Golgi apparatus" "HPA026816: , HPA047533: " "unprognostic (1.17e-1)" "unprognostic (1.92e-1)" "unprognostic (2.82e-1)" "unprognostic (3.55e-1)" "unprognostic (6.12e-2)" "unprognostic (2.04e-1)" "unprognostic (2.01e-3)" "unprognostic (3.32e-1)" "unprognostic (3.26e-3)" "unprognostic (4.28e-2)" "potential prognostic favorable (3.34e-6)" "unprognostic (9.65e-2)" "unprognostic (1.29e-1)" "unprognostic (9.14e-2)" "unprognostic (3.90e-2)" "potential prognostic favorable (8.92e-4)" "unprognostic (9.61e-3)" "unprognostic (5.43e-2)" "unprognostic (1.27e-1)" "unprognostic (3.46e-2)" "unprognostic (8.36e-3)" "unprognostic (5.72e-3)" "unprognostic (1.53e-1)" "unprognostic (1.11e-1)" "unprognostic (1.34e-1)" "unprognostic (9.87e-3)" "unprognostic (1.99e-1)" "unprognostic (1.40e-1)" "unprognostic (7.65e-2)" "unprognostic (1.47e-1)" "unprognostic (4.38e-2)" SEC13 "D3S1231E, npp-20, SEC13L1, SEC13R" ENSG00000157020 "SEC13 homolog, nuclear pore and COPII coat complex component" P55735 3 10293131-10321112 "Essential proteins, Metabolic proteins, Predicted intracellular proteins, Transporters" "ER-Golgi transport, mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 247.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035292, HPA057943" Approved Supported Nucleoplasm,Vesicles NA NA 37000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 60: Stomach - Digestion" "Cluster 21: Non-specific - Metabolism" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Secretory pathway" 93 "Nucleoplasm, Vesicles" "HPA035292: , HPA057943: " "unprognostic (1.17e-1)" "potential prognostic unfavorable (9.84e-4)" "unprognostic (1.00e-1)" "unprognostic (9.73e-2)" "unprognostic (6.97e-2)" "unprognostic (7.93e-2)" "unprognostic (1.09e-1)" "unprognostic (5.50e-2)" "unprognostic (1.94e-1)" "unprognostic (1.98e-3)" "unprognostic (5.44e-2)" "unprognostic (1.64e-2)" "unprognostic (1.61e-1)" "validated prognostic unfavorable (6.70e-5)" "validated prognostic unfavorable (3.19e-5)" "unprognostic (1.99e-3)" "potential prognostic unfavorable (4.23e-4)" "unprognostic (1.73e-1)" "unprognostic (2.41e-1)" "unprognostic (1.72e-1)" "unprognostic (8.84e-2)" "unprognostic (6.72e-2)" "unprognostic (3.20e-1)" "unprognostic (6.97e-2)" "unprognostic (7.90e-3)" "unprognostic (1.32e-1)" "unprognostic (2.39e-1)" "unprognostic (3.39e-1)" "unprognostic (7.68e-2)" "unprognostic (1.08e-3)" "unprognostic (2.26e-1)" SEC14L1 "PRELID4A, SEC14L" ENSG00000129657 "SEC14 like lipid binding 1" Q92503 17 77088749-77217101 "Plasma proteins, Predicted intracellular proteins, Transporters" "Immunity, Innate immunity" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 799.4;Endometrial glandular cells: 529.1;Late spermatids: 1361.1;Neutrophils: 1193.8;Platelets: 851.3;Vascular endothelial cells: 450.0" "Cell type enhanced" "Detected in all" "endothelial cell: 552.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 7 "neutrophil: 356.6" "Lineage enriched" "Detected in all" 11 "granulocytes: 356.6" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Adrenal gland - Adrenal cortex cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Liver - Vascular endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021463, HPA028703" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 4 "Nucleoplasm, Cytosol" "HPA021463: , HPA028703: " "unprognostic (8.28e-2)" "unprognostic (2.15e-1)" "unprognostic (6.99e-2)" "unprognostic (2.83e-1)" "unprognostic (3.24e-1)" "unprognostic (1.72e-1)" "unprognostic (1.58e-1)" "unprognostic (9.78e-3)" "unprognostic (6.88e-2)" "unprognostic (1.91e-2)" "validated prognostic favorable (4.58e-7)" "validated prognostic favorable (2.61e-4)" "unprognostic (5.85e-2)" "unprognostic (3.53e-2)" "unprognostic (1.51e-1)" "unprognostic (6.87e-2)" "unprognostic (7.97e-3)" "unprognostic (3.19e-2)" "potential prognostic favorable (5.16e-4)" "unprognostic (5.43e-2)" "unprognostic (3.88e-2)" "unprognostic (2.97e-2)" "unprognostic (6.42e-3)" "potential prognostic unfavorable (4.26e-4)" "unprognostic (3.83e-2)" "unprognostic (5.94e-2)" "unprognostic (3.15e-1)" "unprognostic (6.91e-2)" "unprognostic (2.50e-1)" "unprognostic (2.01e-1)" "unprognostic (7.17e-2)" SEC14L2 "C22orf6, KIAA1186, KIAA1658, SPF, TAP, TAP1" ENSG00000100003 "SEC14 like lipid binding 2" O76054 22 30396941-30425303 "Predicted intracellular proteins" "Transcription, Transcription regulation, Transport" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 81.2;liver: 227.8" "Cell type enhanced" "Detected in many" "Astrocytes: 67.6;Bergmann glia: 47.1;Esophageal apical cells: 53.3;Hepatocytes: 55.4;Müller glia: 88.8;Retinal pigment epithelial cells: 55.4;Rod photoreceptor cells: 57.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 3.8;naive CD8 T-cell: 2.7" "Lineage enriched" "Detected in single" 7 "T-cells: 3.8" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Breast - Breast glandular cells, Breast - Breast glandular cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064466 Approved Supported Nucleoplasm,Cytosol NA NA 670000 "Cluster 24: Non-specific - Transcription" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 19: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 11: Muller glia cells - Retinal homeostasis" Nucleoplasm Cytosol "HPA064466: " "unprognostic (4.52e-2)" "unprognostic (6.53e-3)" "unprognostic (4.27e-1)" "unprognostic (1.23e-1)" "unprognostic (8.29e-3)" "unprognostic (1.22e-1)" "unprognostic (6.07e-2)" "unprognostic (8.59e-2)" "potential prognostic unfavorable (1.73e-7)" "unprognostic (1.89e-1)" "unprognostic (7.72e-2)" "unprognostic (1.51e-1)" "unprognostic (1.17e-2)" "validated prognostic favorable (2.40e-4)" "validated prognostic favorable (1.34e-4)" "unprognostic (8.65e-3)" "unprognostic (8.59e-3)" "unprognostic (1.20e-1)" "potential prognostic unfavorable (4.12e-5)" "unprognostic (3.49e-1)" "unprognostic (3.81e-2)" "unprognostic (2.32e-3)" "unprognostic (3.49e-2)" "unprognostic (1.81e-1)" "unprognostic (8.99e-2)" "unprognostic (1.52e-2)" "unprognostic (3.63e-2)" "unprognostic (8.01e-2)" "unprognostic (9.94e-2)" "unprognostic (2.46e-3)" "unprognostic (5.10e-3)" SEC14L3 TAP2 ENSG00000100012 "SEC14 like lipid binding 3" Q9UDX4 22 30447959-30472017 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 3.6;liver: 2.7;retina: 8.4" "Cell type enhanced" "Detected in some" "Epicardial cells: 6.8;Erythrocyte progenitors: 17.0;Müller glia: 104.6;Respiratory ciliated cells: 30.8" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes, Lung - Respiratory ciliated cells, Skin - Sebaceous gland cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" HPA059450 Uncertain NA NA "Cluster 40: Non-specific - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 11: Muller glia cells - Retinal homeostasis" "HPA059450: " SEC14L4 "dJ130H16.5, TAP3" ENSG00000133488 "SEC14 like lipid binding 4" Q9UDX3 22 30488902-30505711 "Predicted intracellular proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 7.7;liver: 18.0" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 8.6;Cholangiocytes: 15.7;Erythrocyte progenitors: 25.5;Hepatocytes: 39.0;Müller glia: 9.2;Respiratory ciliated cells: 38.5;Sertoli cells: 51.3;Transitional alveolar cells: 7.4" "Cell type enhanced" "Detected in some" "cerebellar inhibitory: 2.2;lower rhombic lip: 2.6;thalamic excitatory: 2.3" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 4.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Adrenocortical cancer: 4.0" "Adipose visceral - Mesothelial cells, Skin - Sebaceous gland cells, Testis - Sertoli cells" "Region enhanced" "Detected in single" "thalamus: 1.2" "Low region specificity" "Detected in single" HPA066270 Approved Vesicles,Cytosol NA NA 96000 "Cluster 53: Liver - Plasma proteins" "Cluster 6: Non-specific - Immune response" "Cluster 70: DU4475 - Unknown function" "Cluster 93: Hepatocytes - Bile production & excretion" 19 Vesicles Cytosol "HPA066270: " "unprognostic (2.06e-1)" "unprognostic (5.52e-3)" "unprognostic (2.46e-2)" "unprognostic (9.04e-2)" "unprognostic (1.35e-3)" "unprognostic (1.78e-3)" "unprognostic (6.96e-2)" "unprognostic (6.00e-2)" "unprognostic (7.05e-2)" "unprognostic (1.33e-2)" "unprognostic (6.96e-2)" "unprognostic (1.39e-1)" "unprognostic (9.38e-2)" "unprognostic (1.65e-1)" SEC14L5 "KIAA0420, PRELID4B" ENSG00000103184 "SEC14 like lipid binding 5" O43304 16 4958330-5019157 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 35.1;tongue: 10.2" "Group enriched" "Detected in many" 4 "Cone photoreceptor cells: 186.3;Oligodendrocytes: 148.8" "Cell type enhanced" "Detected in many" "oligodendrocyte: 202.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Pituitary gland - Gonadotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041492, HPA041825" Uncertain "Golgi apparatus,Cytosol" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 32: Non-specific - Cell proliferation" "Cluster 79: Photoreceptor cells - Phototransduction" 1 "Golgi apparatus, Cytosol" "HPA041492: , HPA041825: " "unprognostic (3.01e-1)" "unprognostic (6.80e-2)" "unprognostic (6.07e-2)" "unprognostic (1.48e-2)" SEC14L6 ENSG00000214491 "SEC14 like lipid binding 6" B5MCN3 22 30522799-30546741 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "epididymis: 13.8;parathyroid gland: 19.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 11.2;Alveolar cells type 2: 11.8;Distal convoluted tubule cells: 16.8;Epididymal principal cells: 16.9;Loop of henle epithelial cells: 21.2;Müller glia: 31.1;Pancreatic duct cells: 12.5;Renal collecting duct principal cells: 15.2;Sertoli cells: 42.9;Transitional alveolar cells: 15.8" "Cell type enhanced" "Detected in many" "lower rhombic lip: 17.6" "Group enriched" "Detected in many" 6 "Kidney Renal Clear Cell Carcinoma (TCGA): 26.1;Kidney Renal Papillary Cell Carcinoma (TCGA): 21.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 10 "Kidney cancer: 19.8" "Adipose visceral - Mesothelial cells, Colon - Enteric glia cells, Liver - Cholangiocytes, Lung - Alveolar cells type 1, Prostate - Fibroblasts, Skin - Sebaceous gland cells, Testis - Sertoli cells" HPA067695 Approved Nucleoplasm NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" Nucleoplasm "HPA067695: " "unprognostic (1.36e-2)" "unprognostic (2.12e-1)" "unprognostic (1.04e-3)" "unprognostic (2.27e-1)" "validated prognostic favorable (3.82e-4)" "validated prognostic favorable (2.63e-5)" "unprognostic (3.41e-2)" "unprognostic (4.42e-3)" "unprognostic (1.80e-1)" "unprognostic (6.39e-2)" "unprognostic (5.35e-2)" "unprognostic (1.80e-1)" "unprognostic (4.17e-2)" "unprognostic (3.53e-3)" "unprognostic (5.74e-2)" "unprognostic (2.47e-1)" "unprognostic (1.79e-1)" SEC16A "KIAA0310, p250, Sec16L" ENSG00000148396 "SEC16 homolog A, endoplasmic reticulum export factor" O15027 9 136440096-136483759 "Essential proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005684 Supported Supported "Endoplasmic reticulum,Golgi apparatus" NA NA 17000 "Cluster 13: Non-specific - Mitochondria" "Cluster 70: Non-specific - Protein processing" "Cluster 23: Choroid plexus - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 80 "Golgi apparatus" "Endoplasmic reticulum" "HPA005684: " "unprognostic (1.18e-1)" "unprognostic (1.09e-2)" "unprognostic (3.52e-3)" "unprognostic (1.19e-2)" "unprognostic (1.17e-1)" "unprognostic (5.31e-2)" "unprognostic (2.14e-1)" "unprognostic (2.09e-1)" "unprognostic (1.83e-1)" "unprognostic (2.58e-1)" "potential prognostic favorable (2.43e-5)" "unprognostic (7.77e-2)" "unprognostic (2.32e-1)" "unprognostic (1.73e-1)" "unprognostic (3.90e-1)" "unprognostic (2.54e-2)" "unprognostic (9.37e-2)" "unprognostic (1.10e-2)" "unprognostic (1.66e-2)" "unprognostic (1.47e-1)" "unprognostic (1.21e-3)" "unprognostic (1.88e-2)" "unprognostic (1.03e-1)" "unprognostic (3.33e-1)" "unprognostic (1.20e-1)" "unprognostic (1.38e-1)" "unprognostic (1.37e-1)" "unprognostic (9.61e-2)" "unprognostic (1.78e-1)" "unprognostic (4.86e-2)" "unprognostic (4.46e-2)" SEC16B "LZTR2, PGPR-p117, RGPR, Sec16S" ENSG00000120341 "SEC16 homolog B, endoplasmic reticulum export factor" Q96JE7 1 177923956-177984303 "Predicted intracellular proteins" "ER-Golgi transport, Peroxisome biogenesis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 27.7;liver: 38.6" "Cell type enriched" "Detected in some" 4 "Proximal tubule cells: 76.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 16.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA054292, HPA072913" Enhanced Approved "Endoplasmic reticulum,Plasma membrane,Actin filaments" NA NA "Cluster 77: Intestine - Digestion" "Cluster 53: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 88: Proximal tubular cells - Transmembrane transport" 3 "Endoplasmic reticulum, Plasma membrane" "Actin filaments" "HPA054292: , HPA072913: " "unprognostic (7.02e-2)" "unprognostic (9.80e-2)" "unprognostic (1.66e-2)" "unprognostic (1.35e-1)" "unprognostic (2.36e-1)" "unprognostic (2.72e-2)" "unprognostic (1.97e-1)" "unprognostic (9.21e-2)" "unprognostic (2.51e-1)" "unprognostic (3.51e-3)" "unprognostic (9.17e-3)" "unprognostic (3.76e-3)" "unprognostic (6.93e-2)" "potential prognostic favorable (9.15e-4)" "unprognostic (2.04e-2)" "unprognostic (1.85e-1)" "unprognostic (2.10e-2)" "unprognostic (6.03e-2)" "unprognostic (1.64e-1)" "unprognostic (1.21e-1)" "unprognostic (8.35e-2)" "unprognostic (2.45e-1)" "unprognostic (8.93e-2)" "potential prognostic unfavorable (8.43e-4)" "unprognostic (5.55e-2)" "unprognostic (6.69e-3)" "unprognostic (3.15e-1)" "unprognostic (1.77e-1)" "potential prognostic unfavorable (6.75e-4)" SEC22A SEC22L2 ENSG00000121542 "SEC22 homolog A, vesicle trafficking protein" Q96IW7 3 123201927-123274136 "Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039127 Approved "Golgi apparatus,Vesicles" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 57: Testis - Spermatogenesis" "Cluster 31: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 7: Non-specific - Transcription" 94 "Golgi apparatus" Vesicles "HPA039127: " "unprognostic (4.71e-2)" "potential prognostic unfavorable (1.41e-4)" "unprognostic (3.46e-2)" "unprognostic (1.24e-3)" "unprognostic (1.34e-1)" "unprognostic (1.65e-1)" "unprognostic (1.99e-1)" "unprognostic (2.62e-3)" "unprognostic (1.92e-1)" "unprognostic (7.33e-2)" "unprognostic (1.76e-3)" "unprognostic (2.67e-1)" "unprognostic (3.71e-1)" "potential prognostic unfavorable (1.01e-5)" "unprognostic (1.22e-1)" "unprognostic (2.06e-1)" "unprognostic (7.99e-3)" "unprognostic (1.88e-1)" "unprognostic (8.46e-2)" "unprognostic (7.98e-2)" "unprognostic (6.42e-3)" "unprognostic (7.88e-2)" "potential prognostic unfavorable (8.83e-5)" "unprognostic (1.64e-2)" "unprognostic (2.00e-2)" "unprognostic (5.41e-2)" "unprognostic (7.13e-2)" "unprognostic (1.00e-1)" "unprognostic (1.05e-1)" "unprognostic (1.78e-1)" "unprognostic (8.91e-2)" SEC22B "ERS-24, SEC22L1" ENSG00000265808 "SEC22 homolog B, vesicle trafficking protein" O75396 1 120150898-120176520 "Essential proteins, Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 165.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB079017 Approved NA NA 120000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 42: Retina - Visual perception" "Cluster 55: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 128 "CAB079017: " "unprognostic (1.14e-2)" "unprognostic (1.46e-1)" "unprognostic (1.77e-1)" "potential prognostic favorable (7.76e-4)" "unprognostic (7.87e-3)" "unprognostic (7.61e-2)" "unprognostic (2.04e-1)" "unprognostic (2.38e-1)" "unprognostic (3.00e-1)" "unprognostic (1.73e-2)" "unprognostic (1.72e-1)" "unprognostic (5.89e-2)" "unprognostic (6.67e-2)" "unprognostic (1.49e-1)" "unprognostic (9.45e-2)" "unprognostic (2.38e-1)" "unprognostic (3.04e-1)" "unprognostic (8.19e-2)" "unprognostic (3.57e-2)" "unprognostic (1.40e-1)" "unprognostic (6.16e-2)" "unprognostic (4.12e-2)" "unprognostic (1.88e-2)" "unprognostic (6.29e-2)" "unprognostic (3.69e-2)" "unprognostic (1.09e-1)" "potential prognostic unfavorable (8.24e-4)" "unprognostic (9.75e-2)" SEC22C "MGC13261, MGC5373, SEC22L3" ENSG00000093183 "SEC22 homolog C, vesicle trafficking protein" Q9BRL7 3 42547969-42601080 "Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 196.2;Epicardial cells: 134.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031242 Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 58: Mast cells - Allergic inflammatory responses" 3 "Golgi apparatus" Nucleoplasm "HPA031242: " "unprognostic (1.01e-1)" "unprognostic (2.30e-1)" "unprognostic (1.57e-1)" "unprognostic (1.68e-1)" "unprognostic (2.59e-1)" "unprognostic (2.60e-2)" "unprognostic (5.25e-2)" "unprognostic (1.14e-1)" "unprognostic (3.06e-1)" "unprognostic (4.01e-2)" "potential prognostic favorable (1.24e-5)" "unprognostic (3.34e-3)" "unprognostic (3.02e-2)" "unprognostic (2.23e-3)" "unprognostic (5.77e-2)" "unprognostic (1.03e-1)" "unprognostic (3.56e-2)" "unprognostic (4.01e-2)" "unprognostic (6.92e-2)" "unprognostic (2.39e-1)" "unprognostic (1.83e-2)" "unprognostic (6.67e-2)" "unprognostic (1.04e-1)" "unprognostic (3.06e-1)" "unprognostic (5.96e-2)" "unprognostic (8.04e-2)" "unprognostic (2.60e-1)" "unprognostic (2.70e-2)" "unprognostic (3.07e-1)" "unprognostic (6.16e-2)" "unprognostic (7.25e-3)" SEC23A ENSG00000100934 "SEC23 homolog A, COPII coat complex component" Q15436 14 39031919-39109646 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Minor Salivary Gland - Endothelial cells, Prostate - Smooth muscle cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069974 Uncertain Supported "Endoplasmic reticulum,Cytosol" NA NA 35000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 75: Ovary - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 8: Non-specific - Secretory pathway" 66 "Endoplasmic reticulum, Cytosol" "HPA069974: " "unprognostic (1.74e-1)" "unprognostic (1.53e-1)" "unprognostic (3.29e-1)" "potential prognostic unfavorable (7.65e-4)" "unprognostic (1.40e-2)" "unprognostic (2.61e-3)" "unprognostic (2.46e-1)" "unprognostic (1.46e-2)" "unprognostic (2.87e-2)" "unprognostic (3.41e-2)" "potential prognostic favorable (6.89e-4)" "unprognostic (1.24e-1)" "unprognostic (7.76e-2)" "unprognostic (1.13e-2)" "unprognostic (1.04e-1)" "unprognostic (2.30e-3)" "potential prognostic unfavorable (4.70e-5)" "unprognostic (2.62e-1)" "unprognostic (1.60e-1)" "unprognostic (1.98e-3)" "potential prognostic unfavorable (1.84e-4)" "unprognostic (2.25e-2)" "unprognostic (1.13e-1)" "unprognostic (1.23e-1)" "unprognostic (6.09e-2)" "unprognostic (1.27e-1)" "potential prognostic unfavorable (5.40e-4)" "unprognostic (3.12e-3)" "unprognostic (2.99e-1)" "unprognostic (1.48e-1)" "unprognostic (5.73e-2)" SEC23B "CDA-II, CDAII, CDAN2, HEMPAS" ENSG00000101310 "SEC23 homolog B, COPII coat complex component" Q15437 20 18507520-18561415 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Congenital dyserythropoietic anemia, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 186.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Macrophages, Breast - Breast glandular cells, Colon - Macrophages, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008216, HPA069974" Uncertain Supported "Endoplasmic reticulum,Vesicles,Cytosol" NA Yes 5400 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 8: Pancreas - Proteolysis" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 43 "Endoplasmic reticulum, Vesicles, Cytosol" "HPA008216: , HPA069974: " "unprognostic (7.07e-3)" "unprognostic (1.62e-2)" "unprognostic (2.09e-1)" "unprognostic (3.93e-2)" "unprognostic (6.19e-2)" "unprognostic (1.02e-1)" "unprognostic (2.08e-1)" "unprognostic (1.62e-1)" "unprognostic (2.06e-1)" "unprognostic (2.48e-3)" "unprognostic (1.37e-3)" "unprognostic (1.73e-1)" "unprognostic (2.03e-1)" "unprognostic (1.46e-3)" "unprognostic (3.92e-2)" "unprognostic (2.42e-1)" "unprognostic (3.45e-1)" "potential prognostic unfavorable (4.93e-4)" "unprognostic (2.68e-1)" "unprognostic (2.65e-1)" "unprognostic (1.72e-1)" "unprognostic (1.13e-1)" "unprognostic (1.92e-1)" "unprognostic (2.45e-1)" "unprognostic (1.25e-1)" "unprognostic (8.77e-2)" "unprognostic (3.72e-2)" "unprognostic (5.18e-2)" "unprognostic (1.94e-1)" "unprognostic (1.85e-2)" "unprognostic (2.29e-2)" SEC23IP "iPLA1Ã, iPLA1beta, p125, p125A" ENSG00000107651 "SEC23 interacting protein" Q9Y6Y8 10 119892707-119944657 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038403, HPA043305" Approved Enhanced Vesicles NA NA 37000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 22: Epididymis - Mixed function" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 52: Non-specific - Mitochondria" "Cluster 8: Non-specific - Secretory pathway" 24 Vesicles "HPA038403: , HPA043305: " "unprognostic (1.01e-1)" "unprognostic (4.84e-2)" "unprognostic (1.81e-1)" "unprognostic (4.61e-3)" "unprognostic (2.64e-1)" "unprognostic (3.54e-2)" "unprognostic (1.04e-1)" "unprognostic (4.95e-2)" "unprognostic (7.57e-3)" "unprognostic (1.01e-1)" "potential prognostic favorable (4.23e-7)" "unprognostic (1.98e-1)" "unprognostic (3.37e-1)" "unprognostic (1.23e-3)" "unprognostic (3.59e-2)" "unprognostic (4.75e-2)" "unprognostic (2.14e-2)" "unprognostic (4.75e-1)" "unprognostic (1.75e-1)" "unprognostic (9.16e-2)" "potential prognostic unfavorable (4.81e-5)" "potential prognostic unfavorable (2.85e-5)" "unprognostic (2.49e-1)" "unprognostic (1.13e-1)" "unprognostic (9.79e-2)" "unprognostic (2.49e-1)" "unprognostic (1.16e-1)" "unprognostic (2.16e-1)" "unprognostic (1.67e-1)" "unprognostic (1.40e-3)" "unprognostic (2.01e-1)" SEC24A ENSG00000113615 "SEC24 homolog A, COPII coat complex component" O95486 5 134648785-134727909 "Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 250.5;Plasma cells: 251.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038901, HPA056825" Approved Approved "Nucleoli fibrillar center,Vesicles" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 17 "Nucleoli fibrillar center, Vesicles" "HPA038901: , HPA056825: " "unprognostic (2.62e-2)" "unprognostic (2.01e-2)" "unprognostic (4.74e-2)" "potential prognostic unfavorable (9.20e-4)" "unprognostic (3.10e-2)" "unprognostic (7.40e-2)" "unprognostic (3.49e-1)" "potential prognostic unfavorable (1.42e-4)" "unprognostic (6.36e-2)" "potential prognostic unfavorable (4.39e-4)" "unprognostic (2.11e-3)" "unprognostic (3.63e-1)" "unprognostic (3.28e-2)" "unprognostic (1.29e-1)" "unprognostic (5.50e-2)" "unprognostic (1.53e-1)" "unprognostic (2.66e-2)" "unprognostic (4.31e-2)" "unprognostic (2.61e-2)" "unprognostic (1.61e-1)" "potential prognostic unfavorable (8.93e-4)" "unprognostic (1.64e-3)" "unprognostic (1.49e-2)" "unprognostic (1.68e-1)" "unprognostic (5.34e-2)" "unprognostic (2.95e-1)" "unprognostic (2.20e-1)" "unprognostic (8.37e-2)" "unprognostic (1.32e-1)" "unprognostic (2.96e-3)" "unprognostic (3.41e-1)" SEC24B ENSG00000138802 "SEC24 homolog B, COPII coat complex component" O95487 4 109433772-109540896 "Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 418.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038181 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 16: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 22 "Nucleoplasm, Vesicles" "HPA038181: " "unprognostic (1.04e-1)" "unprognostic (1.18e-3)" "unprognostic (2.88e-1)" "potential prognostic unfavorable (4.82e-4)" "unprognostic (1.17e-2)" "unprognostic (3.05e-1)" "unprognostic (1.28e-1)" "unprognostic (9.46e-3)" "unprognostic (3.83e-1)" "potential prognostic unfavorable (3.10e-4)" "validated prognostic favorable (2.87e-8)" "validated prognostic favorable (6.08e-6)" "unprognostic (2.71e-1)" "unprognostic (2.04e-1)" "unprognostic (2.16e-3)" "unprognostic (9.12e-2)" "potential prognostic unfavorable (5.36e-4)" "unprognostic (4.93e-2)" "unprognostic (8.61e-2)" "unprognostic (3.73e-3)" "unprognostic (3.74e-3)" "unprognostic (1.41e-2)" "unprognostic (3.78e-2)" "unprognostic (9.52e-2)" "unprognostic (1.22e-2)" "unprognostic (5.05e-2)" "unprognostic (2.21e-1)" "unprognostic (2.04e-1)" "unprognostic (1.64e-1)" "unprognostic (2.48e-2)" "unprognostic (3.30e-2)" SEC24C KIAA0079 ENSG00000176986 "SEC24 homolog C, COPII coat complex component" P53992 10 73744372-73772161 "Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 194.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040196, HPA040213" Supported Supported Vesicles NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 52: Non-specific - Mitochondria" "Cluster 84: Apical squamous epithelium - Cornification" 23 Vesicles "HPA040196: , HPA040213: " "unprognostic (3.17e-2)" "unprognostic (1.33e-2)" "unprognostic (3.67e-1)" "unprognostic (1.03e-3)" "unprognostic (8.28e-2)" "unprognostic (8.82e-2)" "unprognostic (1.83e-1)" "potential prognostic favorable (1.21e-7)" "unprognostic (1.55e-1)" "unprognostic (1.99e-2)" "potential prognostic favorable (1.01e-4)" "unprognostic (1.33e-1)" "unprognostic (5.07e-1)" "unprognostic (2.31e-3)" "unprognostic (1.60e-2)" "unprognostic (2.78e-1)" "unprognostic (2.94e-2)" "unprognostic (1.19e-2)" "unprognostic (2.88e-2)" "unprognostic (3.78e-2)" "unprognostic (1.04e-1)" "unprognostic (1.16e-1)" "unprognostic (9.25e-3)" "unprognostic (7.36e-2)" "unprognostic (1.54e-1)" "unprognostic (1.80e-1)" "unprognostic (6.38e-2)" "unprognostic (2.92e-2)" "unprognostic (1.67e-1)" "unprognostic (1.45e-1)" "unprognostic (1.11e-1)" SEC24D KIAA0755 ENSG00000150961 "SEC24 homolog D, COPII coat complex component" O94855 4 118722823-118838683 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Craniosynostosis, Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gonadotrophs: 359.6;Lactotrophs: 336.1;Plasma cells: 394.5;Somatotrophs: 413.6" "Cell type enhanced" "Detected in all" "deep-layer corticothalamic and 6b: 262.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041626, HPA053486" Approved Approved Vesicles NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 8: Non-specific - Secretory pathway" 15 Vesicles "HPA041626: , HPA053486: " "unprognostic (1.75e-2)" "unprognostic (1.00e-1)" "unprognostic (1.97e-1)" "unprognostic (1.30e-1)" "unprognostic (3.00e-2)" "unprognostic (1.47e-2)" "unprognostic (7.79e-2)" "unprognostic (1.57e-3)" "unprognostic (3.76e-1)" "unprognostic (2.06e-1)" "unprognostic (6.18e-3)" "unprognostic (3.86e-1)" "unprognostic (7.14e-3)" "unprognostic (7.37e-2)" "unprognostic (4.46e-1)" "unprognostic (8.96e-2)" "unprognostic (9.83e-3)" "unprognostic (9.28e-2)" "unprognostic (2.15e-1)" "unprognostic (4.00e-2)" "unprognostic (9.69e-3)" "unprognostic (1.25e-1)" "unprognostic (6.03e-2)" "unprognostic (1.65e-1)" "unprognostic (8.19e-2)" "unprognostic (3.70e-2)" "unprognostic (1.86e-1)" "unprognostic (9.56e-3)" "unprognostic (4.52e-2)" "unprognostic (1.82e-2)" "unprognostic (1.73e-1)" SEC31A "ABP125, ABP130, KIAA0905, SEC31L1" ENSG00000138674 "SEC31 homolog A, COPII coat complex component" O94979 4 82818509-82901166 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "ER-Golgi transport, Protein transport, Transport" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005457 Approved Supported Vesicles,Cytosol NA NA 40000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 70: Non-specific - Protein processing" "Cluster 31: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 8: Non-specific - Secretory pathway" 35 "Vesicles, Cytosol" "HPA005457: " "unprognostic (8.09e-3)" "unprognostic (3.93e-2)" "unprognostic (1.40e-1)" "unprognostic (1.85e-3)" "unprognostic (2.14e-1)" "potential prognostic unfavorable (2.83e-4)" "unprognostic (4.18e-1)" "unprognostic (1.63e-1)" "unprognostic (3.49e-2)" "unprognostic (2.28e-2)" "potential prognostic favorable (1.77e-5)" "unprognostic (6.74e-3)" "unprognostic (3.37e-2)" "potential prognostic unfavorable (5.11e-4)" "unprognostic (1.68e-1)" "unprognostic (5.87e-3)" "unprognostic (5.15e-3)" "unprognostic (1.34e-2)" "unprognostic (1.60e-1)" "unprognostic (2.67e-1)" "unprognostic (2.05e-1)" "unprognostic (3.17e-2)" "unprognostic (4.32e-2)" "unprognostic (6.70e-2)" "unprognostic (8.09e-2)" "unprognostic (1.23e-1)" "unprognostic (2.63e-1)" "unprognostic (7.66e-3)" "unprognostic (1.34e-1)" "unprognostic (4.78e-2)" "unprognostic (1.19e-2)" SEC31B "DKFZP434M183, SEC31B-1, SEC31L2" ENSG00000075826 "SEC31 homolog B, COPII coat complex component" Q9NQW1 10 100486646-100519864 "Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Myonuclei: 34.6;Retinal amacrine cells: 33.4;Thyrotrophs: 36.7" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 3.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA035882, HPA040819, HPA060052" Uncertain Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 9: Non-specific - Receptor signaling" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "Nucleoplasm, Vesicles, Cytosol" "HPA035882: , HPA040819: , HPA060052: " "unprognostic (2.46e-1)" "unprognostic (1.03e-3)" "potential prognostic favorable (1.70e-5)" "unprognostic (2.49e-2)" "unprognostic (1.04e-2)" SEC61A1 ENSG00000058262 "SEC61 translocon subunit alpha 1" P61619 3 128051641-128071705 "Disease related genes, Essential proteins, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Protein transport, Translocation, Transport" Chaperone "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 249.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022076 Supported "Endoplasmic reticulum" NA NA 140000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 70: Non-specific - Protein processing" "Cluster 44: Non-specific - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 8: Non-specific - Secretory pathway" 63 "Endoplasmic reticulum" "CAB022076: " "unprognostic (2.19e-1)" "unprognostic (1.19e-1)" "unprognostic (6.41e-2)" "unprognostic (2.82e-3)" "unprognostic (1.43e-1)" "unprognostic (1.17e-1)" "unprognostic (7.47e-2)" "unprognostic (1.70e-1)" "unprognostic (8.44e-2)" "unprognostic (1.22e-2)" "unprognostic (1.74e-3)" "unprognostic (7.25e-3)" "unprognostic (6.99e-2)" "potential prognostic unfavorable (6.29e-5)" "unprognostic (1.82e-2)" "unprognostic (2.63e-2)" "unprognostic (7.26e-3)" "unprognostic (8.20e-2)" "unprognostic (3.66e-2)" "unprognostic (1.35e-1)" "unprognostic (1.26e-1)" "unprognostic (1.06e-2)" "unprognostic (1.27e-1)" "unprognostic (2.22e-1)" "unprognostic (5.27e-2)" "unprognostic (3.50e-1)" "unprognostic (2.20e-1)" "unprognostic (1.61e-1)" "unprognostic (1.80e-1)" "unprognostic (3.81e-3)" "unprognostic (5.10e-1)" SEC61A2 FLJ10578 ENSG00000065665 "SEC61 translocon subunit alpha 2" Q9H9S3 10 12129637-12169961 "Predicted membrane proteins, Transporters" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 31.5" "Cell type enhanced" "Detected in many" "Neutrophils: 88.9;Retinal horizontal cells: 80.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 34: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 24: Neutrophils - Innate immunity signal integration" 5 "unprognostic (1.32e-2)" "unprognostic (4.64e-2)" "unprognostic (1.55e-1)" "unprognostic (1.50e-1)" "unprognostic (1.05e-1)" "unprognostic (1.93e-1)" "unprognostic (2.24e-1)" "potential prognostic favorable (5.06e-5)" "unprognostic (1.92e-2)" "unprognostic (2.83e-2)" "potential prognostic unfavorable (1.47e-5)" "unprognostic (8.13e-3)" "potential prognostic unfavorable (6.31e-4)" "potential prognostic unfavorable (4.95e-4)" "unprognostic (2.54e-1)" "unprognostic (2.88e-2)" "unprognostic (6.70e-3)" "unprognostic (3.30e-1)" "unprognostic (3.49e-3)" "unprognostic (1.23e-1)" "unprognostic (1.47e-1)" "potential prognostic favorable (3.88e-4)" "potential prognostic unfavorable (8.37e-4)" "unprognostic (7.03e-2)" "unprognostic (1.44e-1)" "unprognostic (7.41e-3)" "unprognostic (2.16e-1)" "unprognostic (1.29e-1)" "unprognostic (1.64e-1)" "unprognostic (3.37e-2)" "unprognostic (2.52e-1)" SEC61B ENSG00000106803 "SEC61 translocon subunit beta" P60468 9 99222064-99230615 "Disease related genes, Essential proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epididymal principal cells: 1472.3;pDCs: 1285.2;Plasma cells: 1331.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049407 Approved Supported "Endoplasmic reticulum" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 70: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 55: Lymphoma - Immune response" "Cluster 8: Non-specific - Secretory pathway" 386 "Endoplasmic reticulum" "HPA049407: " "unprognostic (1.28e-1)" "unprognostic (4.87e-2)" "unprognostic (8.65e-2)" "potential prognostic favorable (3.35e-4)" "unprognostic (1.21e-1)" "unprognostic (1.62e-1)" "potential prognostic unfavorable (3.07e-4)" "unprognostic (1.66e-1)" "unprognostic (1.40e-3)" "unprognostic (2.25e-1)" "unprognostic (1.66e-3)" "unprognostic (3.03e-2)" "unprognostic (1.76e-2)" "unprognostic (2.86e-3)" "unprognostic (4.89e-2)" "unprognostic (1.14e-2)" "unprognostic (8.34e-2)" "unprognostic (5.97e-2)" "unprognostic (1.07e-1)" "unprognostic (2.44e-1)" "unprognostic (1.76e-1)" "unprognostic (1.78e-1)" "unprognostic (2.66e-1)" "unprognostic (7.35e-2)" "unprognostic (2.82e-1)" "unprognostic (1.03e-1)" "unprognostic (1.29e-1)" "unprognostic (1.55e-1)" "unprognostic (2.52e-1)" "unprognostic (4.22e-1)" "unprognostic (8.07e-3)" SEC61G SSS1 ENSG00000132432 "SEC61 translocon subunit gamma" P60059 7 54752250-54759974 "Essential proteins, Predicted membrane proteins, Transporters" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 1047.3;Esophageal apical cells: 1338.5;Extravillous trophoblasts: 1051.0;Gastric chief cells: 1047.3;Gastric progenitor cells: 1930.2;Parietal cells: 1124.4" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 6 "Glioblastoma Multiforme (TCGA): 3303.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053196 Uncertain NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 70: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 67: Non-specific - Unknown function" "Cluster 67: Plasma cells - Plasma cell differentiation" 26 "HPA053196: " "unprognostic (1.06e-2)" "potential prognostic unfavorable (2.43e-5)" "unprognostic (1.29e-1)" "unprognostic (1.02e-1)" "unprognostic (2.33e-2)" "unprognostic (1.24e-1)" "unprognostic (6.62e-3)" "unprognostic (2.83e-2)" "potential prognostic unfavorable (4.81e-7)" "potential prognostic unfavorable (1.89e-4)" "unprognostic (1.45e-3)" "unprognostic (4.96e-3)" "unprognostic (1.00e-2)" "validated prognostic unfavorable (4.80e-8)" "validated prognostic unfavorable (1.20e-7)" "validated prognostic unfavorable (4.45e-7)" "validated prognostic unfavorable (4.65e-4)" "unprognostic (2.16e-1)" "unprognostic (2.63e-1)" "unprognostic (3.24e-2)" "unprognostic (1.57e-1)" "unprognostic (8.44e-3)" "potential prognostic unfavorable (1.18e-4)" "unprognostic (2.42e-2)" "unprognostic (7.08e-2)" "unprognostic (3.20e-2)" "unprognostic (2.32e-1)" "unprognostic (1.39e-1)" "unprognostic (1.43e-1)" "unprognostic (6.14e-3)" "unprognostic (1.63e-1)" SEC62 "Dtrp1, HTP1, TLOC1" ENSG00000008952 "SEC62 homolog, preprotein translocation factor" Q99442 3 169966635-169998373 "Predicted membrane proteins, Transporters" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Gastric chief cells: 991.6;Hepatocytes: 1165.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Stomach - Chief cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014059, HPA061450" Approved Approved "Endoplasmic reticulum,Intermediate filaments" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 22: Epididymis - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 8: Non-specific - Secretory pathway" 60 "Endoplasmic reticulum" "Intermediate filaments" "HPA014059: , HPA061450: " "unprognostic (2.00e-1)" "unprognostic (2.44e-1)" "unprognostic (2.93e-2)" "unprognostic (1.80e-2)" "unprognostic (3.53e-1)" "unprognostic (5.04e-2)" "unprognostic (3.37e-1)" "unprognostic (1.66e-3)" "potential prognostic unfavorable (9.90e-4)" "unprognostic (3.45e-3)" "validated prognostic favorable (3.93e-8)" "validated prognostic favorable (2.01e-4)" "unprognostic (1.31e-1)" "unprognostic (2.30e-1)" "unprognostic (3.47e-1)" "unprognostic (1.99e-1)" "unprognostic (1.22e-1)" "unprognostic (4.30e-1)" "unprognostic (2.67e-2)" "unprognostic (2.25e-1)" "potential prognostic unfavorable (2.48e-6)" "potential prognostic unfavorable (7.15e-4)" "unprognostic (8.22e-2)" "unprognostic (1.99e-1)" "unprognostic (1.94e-1)" "unprognostic (2.82e-1)" "unprognostic (2.38e-2)" "unprognostic (7.67e-2)" "unprognostic (2.85e-1)" "unprognostic (2.41e-1)" "unprognostic (1.99e-1)" SEC63 "DNAJC23, ERdj2, PRO2507, SEC63L" ENSG00000025796 "SEC63 homolog, protein translocation regulator" Q9UGP8 6 107867756-107958208 "Disease related genes, Essential proteins, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Protein transport, Transport" Chaperone "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053295, HPA060535" Supported Supported "Endoplasmic reticulum" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 28: Non-specific - Nuclear processes" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 69 "Endoplasmic reticulum" "HPA053295: , HPA060535: " "unprognostic (9.30e-2)" "unprognostic (1.37e-3)" "unprognostic (6.71e-2)" "potential prognostic unfavorable (1.23e-4)" "unprognostic (2.70e-1)" "unprognostic (2.93e-2)" "unprognostic (2.04e-2)" "unprognostic (4.58e-2)" "unprognostic (1.44e-1)" "potential prognostic unfavorable (1.15e-4)" "potential prognostic favorable (9.12e-5)" "unprognostic (2.29e-2)" "unprognostic (3.57e-2)" "unprognostic (1.28e-2)" "unprognostic (1.98e-2)" "unprognostic (4.71e-1)" "unprognostic (8.00e-2)" "unprognostic (1.50e-2)" "unprognostic (1.64e-1)" "unprognostic (5.79e-3)" "unprognostic (3.01e-2)" "unprognostic (5.51e-2)" "unprognostic (2.54e-3)" "unprognostic (1.91e-1)" "unprognostic (8.69e-2)" "unprognostic (1.02e-1)" "unprognostic (6.02e-1)" "unprognostic (5.41e-2)" "unprognostic (1.72e-1)" "unprognostic (4.40e-1)" "unprognostic (8.34e-2)" SECISBP2 SBP2 ENSG00000187742 "SECIS binding protein 2" Q96T21 9 89318500-89359663 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein biosynthesis" RNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 459.8;Late spermatids: 697.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044314, HPA054905" Approved Supported Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 47: Testis - Mixed function" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Transcription" 3 Nucleoplasm "HPA044314: , HPA054905: " "unprognostic (7.38e-2)" "unprognostic (2.53e-2)" "unprognostic (4.57e-2)" "unprognostic (2.35e-1)" "unprognostic (3.87e-2)" "unprognostic (2.36e-2)" "unprognostic (6.49e-2)" "unprognostic (1.20e-2)" "unprognostic (3.24e-1)" "unprognostic (1.38e-1)" "validated prognostic favorable (1.56e-5)" "validated prognostic favorable (2.05e-4)" "unprognostic (2.10e-3)" "unprognostic (5.98e-2)" "unprognostic (2.71e-1)" "unprognostic (6.19e-2)" "unprognostic (1.35e-1)" "unprognostic (1.74e-1)" "unprognostic (7.55e-3)" "unprognostic (1.08e-1)" "unprognostic (2.72e-1)" "unprognostic (1.14e-2)" "unprognostic (7.88e-2)" "unprognostic (1.18e-1)" "unprognostic (5.71e-3)" "unprognostic (3.43e-1)" "unprognostic (1.18e-1)" "unprognostic (1.19e-1)" "unprognostic (1.59e-1)" "unprognostic (2.80e-2)" "unprognostic (4.33e-1)" SECISBP2L KIAA0256 ENSG00000138593 "SECIS binding protein 2 like" Q93073 15 48988476-49046447 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Syncytiotrophoblasts: 1821.1" "Cell type enhanced" "Detected in all" "oligodendrocyte: 598.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039875 Approved Approved Nucleoplasm NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 60: Prostate cancer - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 7 Nucleoplasm "HPA039875: " "unprognostic (2.08e-2)" "unprognostic (5.37e-3)" "unprognostic (1.53e-1)" "unprognostic (4.02e-3)" "unprognostic (6.65e-2)" "unprognostic (1.38e-1)" "unprognostic (9.10e-2)" "unprognostic (1.38e-1)" "unprognostic (2.88e-2)" "unprognostic (4.25e-2)" "validated prognostic favorable (1.07e-8)" "validated prognostic favorable (6.25e-5)" "unprognostic (1.85e-2)" "unprognostic (3.13e-1)" "unprognostic (1.13e-1)" "unprognostic (9.33e-2)" "unprognostic (5.53e-2)" "unprognostic (1.87e-2)" "unprognostic (8.67e-2)" "unprognostic (2.07e-2)" "unprognostic (3.50e-2)" "unprognostic (1.96e-1)" "unprognostic (5.71e-3)" "unprognostic (9.34e-2)" "unprognostic (8.00e-2)" "unprognostic (1.36e-1)" "unprognostic (1.56e-1)" "unprognostic (2.01e-2)" "unprognostic (5.08e-1)" "unprognostic (4.01e-2)" "unprognostic (3.03e-1)" SECTM1 K12 ENSG00000141574 "Secreted and transmembrane 1" Q8WVN6 17 82321024-82334074 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 85.0" "Cell type enhanced" "Detected in many" "cDC: 23.4;Colonocytes: 35.5;Enterocytes: 74.3;Foveolar cells: 51.7;Kupffer cells: 37.9;Macrophages: 28.2;monocytes: 80.6;Neutrophils: 134.1;Oocytes: 27.6;Salivary acinar cells: 24.5" "Cell type enriched" "Detected in single" 14 "leukocyte: 8.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 155.2" "Group enriched" "Detected in many" 13 "granulocytes: 155.2;monocytes: 58.3" "Low cancer specificity" "Detected in many" "Adrenal gland - Macrophages, Minor Salivary Gland - Minor salivary glandular cells, Spleen - Macrophages" "Low region specificity" "Detected in many" HPA051214 Approved "Secreted to blood" "No annotated function" NA NA 14000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 5: Spleen - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 27: Breast cancer - Unknown function" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 5 "HPA051214: " "unprognostic (1.04e-1)" "unprognostic (8.32e-2)" "unprognostic (2.29e-2)" "unprognostic (4.55e-2)" "unprognostic (4.02e-1)" "unprognostic (7.35e-2)" "unprognostic (2.88e-2)" "unprognostic (4.14e-3)" "unprognostic (2.20e-2)" "unprognostic (1.96e-1)" "unprognostic (8.83e-2)" "unprognostic (1.02e-1)" "potential prognostic favorable (2.01e-4)" "unprognostic (2.37e-2)" "unprognostic (8.25e-3)" "unprognostic (3.94e-2)" "unprognostic (1.51e-2)" "unprognostic (1.68e-1)" "unprognostic (2.40e-1)" "unprognostic (5.24e-2)" "unprognostic (3.83e-1)" "unprognostic (2.82e-2)" "unprognostic (4.75e-2)" "unprognostic (1.20e-1)" "unprognostic (1.92e-1)" "unprognostic (2.33e-1)" "unprognostic (3.72e-2)" "unprognostic (1.53e-1)" "unprognostic (9.40e-3)" "unprognostic (2.22e-1)" "unprognostic (6.65e-2)" SEH1L "SEC13L, Seh1, SEH1A, SEH1B" ENSG00000085415 "SEH1 like nucleoporin" Q96EE3 18 12947133-12987536 "Essential proteins, Metabolic proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Chromosome partition, Mitosis, mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039964 Uncertain NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 17: Non-specific - RNA processing" 29 "HPA039964: " "unprognostic (9.26e-2)" "unprognostic (2.35e-1)" "unprognostic (1.83e-1)" "unprognostic (1.55e-1)" "unprognostic (1.15e-1)" "unprognostic (1.38e-1)" "unprognostic (3.29e-1)" "unprognostic (2.09e-1)" "unprognostic (2.52e-2)" "potential prognostic unfavorable (1.45e-4)" "potential prognostic favorable (1.81e-4)" "unprognostic (1.52e-2)" "unprognostic (9.04e-2)" "unprognostic (1.15e-3)" "potential prognostic unfavorable (3.22e-5)" "unprognostic (2.58e-2)" "unprognostic (5.19e-2)" "unprognostic (1.49e-1)" "unprognostic (3.88e-2)" "unprognostic (5.19e-2)" "unprognostic (9.36e-2)" "unprognostic (9.46e-3)" "unprognostic (8.21e-3)" "unprognostic (3.63e-2)" "unprognostic (1.93e-1)" "unprognostic (1.65e-1)" "unprognostic (3.67e-2)" "unprognostic (7.19e-2)" "unprognostic (3.42e-1)" "unprognostic (4.20e-2)" "unprognostic (2.20e-1)" SEL1L "Hrd3, IBD2, SEL1L1" ENSG00000071537 "SEL1L adaptor subunit of ERAD E3 ubiquitin ligase" Q9UBV2 14 81471547-81533853 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction, Notch signaling pathway" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "pancreas: 380.4" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 399.9;Pancreatic acinar cells: 496.4;Plasma cells: 355.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024267 Enhanced "Intracellular and membrane" Other NA NA 41000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 8: Pancreas - Proteolysis" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 67: Plasma cells - Plasma cell differentiation" 50 "HPA024267: " "unprognostic (1.34e-1)" "unprognostic (3.88e-1)" "unprognostic (2.59e-1)" "unprognostic (6.04e-2)" "unprognostic (1.54e-1)" "unprognostic (4.60e-2)" "unprognostic (3.57e-1)" "unprognostic (3.74e-2)" "unprognostic (8.15e-2)" "unprognostic (3.18e-2)" "potential prognostic favorable (1.12e-4)" "unprognostic (3.43e-1)" "unprognostic (2.62e-1)" "unprognostic (2.48e-1)" "unprognostic (4.33e-2)" "unprognostic (1.36e-1)" "unprognostic (7.97e-2)" "unprognostic (1.16e-1)" "unprognostic (1.30e-1)" "unprognostic (3.46e-1)" "potential prognostic unfavorable (5.79e-4)" "unprognostic (2.05e-3)" "unprognostic (2.06e-3)" "unprognostic (5.27e-1)" "unprognostic (6.88e-2)" "unprognostic (2.07e-1)" "unprognostic (6.45e-2)" "unprognostic (1.47e-1)" "unprognostic (1.47e-1)" "unprognostic (1.85e-2)" "unprognostic (1.70e-1)" SEL1L2 "C20orf50, DKFZp434C1826" ENSG00000101251 "SEL1L2 adaptor subunit of ERAD E3 ligase" Q5TEA6 20 13849247-13996443 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 40 "testis: 6.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 118.2;Early primary spermatocytes: 28.3;Early spermatids: 190.5;Epicardial cells: 50.0;Late primary spermatocytes: 196.1;Late spermatids: 240.7" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA059121 Approved NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" "HPA059121: " SEL1L3 KIAA0746 ENSG00000091490 "SEL1L family member 3" Q68CR1 4 25747433-25863760 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 120.2" "Cell type enhanced" "Detected in many" "B-cells: 603.6;Foveolar cells: 251.5;pDCs: 687.6;Plasma cells: 640.3;Transitional alveolar cells: 245.5" "Cell type enhanced" "Detected in all" "deep-layer near-projecting: 305.2;upper rhombic lip: 382.3" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebellum: 175.6" "Group enriched" "Detected in many" 4 "memory B-cell: 42.1;naive B-cell: 42.0;plasmacytoid DC: 38.3" "Group enriched" "Detected in many" 4 "B-cells: 42.1;dendritic cells: 38.3" "Low cancer specificity" "Detected in many" "Breast - Plasma cells" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 7 "cerebellum: 129.1" "HPA039355, HPA040045, HPA058792" Approved Uncertain Mitochondria NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 35: Non-specific - DNA binding" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" Mitochondria "HPA039355: , HPA040045: , HPA058792: " "unprognostic (4.05e-3)" "unprognostic (3.87e-2)" "unprognostic (3.64e-1)" "unprognostic (1.05e-1)" "unprognostic (5.53e-3)" "unprognostic (5.86e-1)" "unprognostic (1.17e-3)" "unprognostic (1.65e-3)" "unprognostic (2.35e-1)" "unprognostic (5.67e-2)" "potential prognostic favorable (2.11e-6)" "unprognostic (9.76e-2)" "unprognostic (8.22e-2)" "unprognostic (4.48e-2)" "unprognostic (3.58e-2)" "unprognostic (1.20e-1)" "unprognostic (1.41e-1)" "unprognostic (5.24e-2)" "unprognostic (9.01e-2)" "unprognostic (6.59e-2)" "unprognostic (3.26e-1)" "unprognostic (3.25e-2)" "unprognostic (4.27e-1)" "unprognostic (7.75e-2)" "unprognostic (2.70e-2)" "unprognostic (1.83e-1)" "unprognostic (3.35e-2)" "unprognostic (2.40e-2)" "unprognostic (2.80e-1)" "unprognostic (1.48e-2)" "unprognostic (1.46e-1)" SELE "CD62E, ELAM, ELAM1, ESEL" ENSG00000007908 "Selectin E" P16581 1 169722640-169764705 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 52.2" "Cell type enriched" "Detected in some" 26 "Vascular endothelial cells: 802.1" "Cell type enriched" "Detected in some" 27 "endothelial cell: 45.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" CAB002143 Enhanced NA NA 68000000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 12: Non-specific - Vasculature" "Cluster 27: Breast cancer - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 3 "CAB002143: " "unprognostic (1.21e-2)" "unprognostic (1.71e-1)" "unprognostic (3.74e-1)" "unprognostic (1.49e-2)" "unprognostic (2.46e-1)" "unprognostic (3.20e-2)" "unprognostic (1.07e-2)" "unprognostic (5.84e-2)" "unprognostic (4.77e-2)" "potential prognostic favorable (2.54e-4)" "unprognostic (2.41e-3)" "potential prognostic favorable (1.02e-4)" "unprognostic (2.23e-1)" "unprognostic (1.14e-1)" "unprognostic (2.31e-1)" "unprognostic (2.64e-1)" "unprognostic (1.35e-1)" "unprognostic (4.40e-1)" "unprognostic (2.00e-2)" "unprognostic (8.03e-2)" "unprognostic (9.39e-3)" "unprognostic (4.51e-1)" "unprognostic (1.02e-2)" "unprognostic (1.67e-2)" SELENBP1 "hSBP, hSP56, LPSB" ENSG00000143416 "Selenium binding protein 1" Q13228 1 151364304-151372707 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein transport, Transport" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 509.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 317.8;Breast lactating cells: 233.5;Colonocytes: 1398.6;Enteric stem cells: 375.8;Enteric transient amplifying cells: 446.1;Hepatocytes: 591.4;Paneth cells: 278.5" "Cell type enhanced" "Detected in some" "astrocyte: 46.7;fibroblast: 41.2;pericyte: 67.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "myeloid DC: 2.4" "Lineage enhanced" "Detected in single" "dendritic cells: 2.4" "Group enriched" "Detected in many" 4 "breast cancer: 93.5;colorectal cancer: 126.9;prostate cancer: 110.8" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005741, CAB008366, HPA011731" Enhanced Supported Nucleoli NA NA 50000000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 77: Intestine - Digestion" "Cluster 39: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 33 Nucleoli "CAB008366: , HPA005741: , HPA011731: " "unprognostic (4.99e-2)" "unprognostic (2.04e-2)" "unprognostic (1.08e-1)" "unprognostic (7.67e-2)" "unprognostic (1.09e-2)" "unprognostic (4.27e-3)" "unprognostic (1.12e-1)" "unprognostic (7.67e-3)" "unprognostic (1.90e-3)" "unprognostic (4.60e-2)" "unprognostic (3.95e-2)" "unprognostic (1.00e-2)" "unprognostic (2.73e-3)" "unprognostic (8.36e-3)" "unprognostic (1.19e-3)" "potential prognostic favorable (4.52e-4)" "unprognostic (1.12e-1)" "unprognostic (1.22e-1)" "unprognostic (1.34e-1)" "unprognostic (1.62e-2)" "unprognostic (9.99e-2)" "unprognostic (2.84e-1)" "unprognostic (6.91e-3)" "unprognostic (3.00e-1)" "unprognostic (1.35e-2)" "unprognostic (2.60e-3)" "potential prognostic unfavorable (8.46e-4)" "unprognostic (1.08e-1)" "unprognostic (1.49e-1)" "unprognostic (2.33e-2)" "unprognostic (2.70e-2)" SELENOF SEP15 ENSG00000183291 "Selenoprotein F" O60613 1 86862445-86914424 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" "No annotated function" NA No 520000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 22: Epididymis - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 37: Non-specific - mRNA processing" "Cluster 108: Fibroblasts - ECM organization" 8 "unprognostic (1.74e-1)" "unprognostic (1.01e-1)" "unprognostic (1.56e-2)" "unprognostic (2.03e-2)" "unprognostic (7.50e-3)" "unprognostic (1.96e-1)" "unprognostic (1.05e-2)" "unprognostic (6.24e-3)" "unprognostic (6.40e-2)" "potential prognostic favorable (3.10e-5)" "unprognostic (1.68e-1)" "unprognostic (9.73e-2)" "potential prognostic unfavorable (1.15e-5)" "unprognostic (4.06e-2)" "unprognostic (3.37e-1)" "unprognostic (1.46e-1)" "unprognostic (1.50e-1)" "unprognostic (2.34e-1)" "unprognostic (3.03e-1)" "unprognostic (4.67e-2)" "unprognostic (8.51e-2)" "unprognostic (1.52e-1)" "unprognostic (4.01e-2)" "unprognostic (2.13e-1)" "unprognostic (1.31e-1)" "unprognostic (3.93e-2)" "unprognostic (2.67e-1)" "unprognostic (1.30e-1)" "unprognostic (1.53e-1)" SELENOH "C11orf31, SELH" ENSG00000211450 "Selenoprotein H" Q8IZQ5 11 57741491-57743554 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 111.4;Enteric stem cells: 114.3;Enteric transient amplifying cells: 125.3;Enterocytes: 111.1;Epididymal efferent duct absorptive cells: 131.4;Epididymal efferent duct ciliated cells: 124.7;Epididymal principal cells: 189.9;Gastric chief cells: 131.0;Goblet cells: 111.5;Neuroendocrine cells: 102.2;Paneth cells: 96.7;Parietal cells: 102.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" HPA048362 Uncertain Approved Nucleoplasm,Nucleoli No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 24: Non-specific - Unknown function" "Cluster 15: Non-specific - Protein processing" 3 "Nucleoplasm, Nucleoli" "HPA048362: " "unprognostic (2.35e-1)" "unprognostic (3.01e-2)" "unprognostic (1.46e-1)" "unprognostic (2.51e-1)" "unprognostic (5.21e-2)" "unprognostic (1.25e-1)" "unprognostic (8.46e-2)" "unprognostic (4.07e-2)" "unprognostic (5.34e-3)" "unprognostic (3.86e-2)" "unprognostic (1.69e-1)" "unprognostic (2.87e-1)" "potential prognostic unfavorable (5.44e-6)" "unprognostic (1.13e-1)" "unprognostic (1.81e-2)" "unprognostic (1.21e-1)" "unprognostic (3.24e-1)" "potential prognostic favorable (2.79e-5)" "unprognostic (4.19e-2)" "unprognostic (1.43e-1)" "unprognostic (4.02e-1)" "unprognostic (1.64e-2)" "unprognostic (7.02e-2)" "unprognostic (6.99e-3)" "potential prognostic unfavorable (9.98e-4)" "unprognostic (1.63e-1)" "unprognostic (3.47e-2)" "unprognostic (3.51e-1)" "unprognostic (7.37e-2)" SELENOI "EPT1, KIAA1724, SELI, SEPI" ENSG00000138018 "Selenoprotein I" Q9C0D9 2 26308547-26395885 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Transferase "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064125 Approved NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 34: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 65: Non-specific - Cell growth & division" 6 "HPA064125: " "unprognostic (2.42e-2)" "unprognostic (4.44e-2)" "unprognostic (7.65e-3)" "unprognostic (4.19e-2)" "unprognostic (3.46e-1)" "unprognostic (9.36e-2)" "unprognostic (2.07e-1)" "unprognostic (1.19e-2)" "potential prognostic unfavorable (7.64e-4)" "potential prognostic favorable (7.45e-5)" "unprognostic (1.39e-1)" "unprognostic (8.63e-3)" "unprognostic (5.05e-3)" "unprognostic (1.12e-2)" "unprognostic (1.20e-1)" "unprognostic (4.85e-2)" "unprognostic (2.68e-2)" "unprognostic (8.23e-2)" "unprognostic (3.18e-1)" "unprognostic (1.48e-2)" "unprognostic (3.06e-2)" "unprognostic (5.72e-2)" "unprognostic (6.25e-2)" "unprognostic (2.84e-1)" "unprognostic (1.74e-1)" "unprognostic (4.24e-1)" "unprognostic (4.89e-1)" "unprognostic (9.72e-3)" "unprognostic (2.15e-1)" SELENOK SELK ENSG00000113811 "Selenoprotein K" Q9Y6D0 3 53884417-53891885 "Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal efferent duct absorptive cells: 756.7;Epididymal principal cells: 1379.1;Goblet cells: 799.0;Late spermatids: 1531.1;Plasma cells: 736.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "basophil: 326.8" "Lineage enriched" "Detected in all" 8 "granulocytes: 326.8" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008196 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 41: Basophils - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 50: Lymphoma - Unknown function" "Cluster 103: Non-specific - Basic cellular processes" 28 "Nucleoplasm, Cytosol" "HPA008196: " "unprognostic (1.91e-1)" "unprognostic (1.09e-1)" "unprognostic (7.65e-3)" "unprognostic (1.38e-1)" "unprognostic (8.18e-2)" "unprognostic (3.06e-1)" "unprognostic (9.33e-2)" "unprognostic (1.07e-1)" "unprognostic (2.06e-2)" "unprognostic (2.46e-1)" "unprognostic (7.54e-2)" "unprognostic (1.15e-1)" "potential prognostic unfavorable (2.13e-4)" "unprognostic (1.69e-3)" "unprognostic (4.50e-1)" "unprognostic (2.35e-1)" "unprognostic (2.72e-1)" "unprognostic (3.14e-2)" "unprognostic (4.27e-2)" "unprognostic (1.49e-1)" "unprognostic (1.09e-2)" "unprognostic (1.77e-1)" "unprognostic (9.68e-2)" "unprognostic (6.85e-2)" "unprognostic (2.51e-1)" "unprognostic (8.62e-3)" "unprognostic (1.53e-2)" "unprognostic (1.35e-1)" "unprognostic (1.12e-1)" SELENOM "SELM, SEPM" ENSG00000198832 "Selenoprotein M" Q8WWX9 22 31104772-31120069 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 874.6" "Cell type enhanced" "Detected in many" "Breast lactating cells: 997.7;Breast myoepithelial cells: 760.3;Decidual stromal cells: 1338.1;Fibroblasts: 487.3;Late spermatids: 745.7;Smooth muscle cells: 1485.5;Vascular smooth muscle cells: 952.7" "Cell type enhanced" "Detected in all" "vascular associated smooth muscle cell: 267.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "B-cells: 155.5;T-cells: 233.8" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008667, HPA019601" Approved Approved Nucleoplasm,Cytosol "Intracellular and membrane" "No annotated function" NA NA 240000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 74: Non-specific - Signal transduction" "Cluster 21: Non-specific - Metabolism" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 10 "Nucleoplasm, Cytosol" "CAB008667: , HPA019601: " "unprognostic (3.72e-1)" "unprognostic (6.11e-3)" "unprognostic (8.18e-2)" "unprognostic (2.23e-1)" "unprognostic (1.23e-1)" "unprognostic (2.10e-3)" "potential prognostic unfavorable (2.20e-4)" "unprognostic (9.49e-2)" "unprognostic (4.06e-2)" "unprognostic (1.37e-3)" "unprognostic (8.64e-2)" "potential prognostic unfavorable (4.90e-4)" "unprognostic (2.22e-3)" "unprognostic (7.11e-2)" "unprognostic (1.90e-1)" "unprognostic (3.31e-1)" "unprognostic (2.38e-1)" "unprognostic (1.19e-1)" "unprognostic (5.37e-2)" "unprognostic (2.39e-3)" "unprognostic (1.51e-1)" "unprognostic (1.44e-1)" "unprognostic (1.63e-2)" "unprognostic (4.55e-2)" "unprognostic (1.23e-2)" "unprognostic (1.36e-2)" "unprognostic (1.96e-1)" "unprognostic (4.28e-2)" "unprognostic (2.44e-1)" SELENON "MDRS1, RSMD1, RSS, SELN, SEPN1" ENSG00000162430 "Selenoprotein N" Q9NZV5 1 25800193-25818221 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Desmin-related myopathy, Disease variant, Myofibrillar myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Lymphatic endothelial cells: 14.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058076 Approved Uncertain Cytosol "Intracellular and membrane" Enzyme NA NA "Cluster 41: Basophils - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 44: Non-specific - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 1 Cytosol "HPA058076: " "unprognostic (4.06e-2)" "unprognostic (6.05e-2)" "unprognostic (2.63e-2)" "unprognostic (6.62e-2)" "unprognostic (2.13e-1)" "unprognostic (5.24e-2)" "unprognostic (2.83e-2)" "unprognostic (1.16e-1)" "unprognostic (4.63e-2)" "unprognostic (7.21e-2)" "unprognostic (8.58e-2)" "unprognostic (2.06e-1)" "potential prognostic unfavorable (1.00e-5)" "unprognostic (3.10e-1)" "unprognostic (3.39e-1)" "unprognostic (1.54e-1)" "unprognostic (4.05e-1)" "unprognostic (1.41e-2)" "unprognostic (2.42e-3)" "unprognostic (4.23e-1)" "unprognostic (1.07e-2)" "unprognostic (2.08e-1)" "unprognostic (8.22e-2)" "unprognostic (8.34e-2)" "unprognostic (1.33e-1)" "unprognostic (2.04e-1)" "unprognostic (3.58e-2)" "unprognostic (4.85e-2)" "potential prognostic favorable (7.44e-4)" SELENOO SELO ENSG00000073169 "Selenoprotein O" Q9BVL4 22 50201011-50217616 "Enzymes, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 26.5" "Cell type enhanced" "Detected in all" "Hepatocytes: 151.9;Late spermatids: 267.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA071795, HPA079100" Approved Supported "Mitotic chromosome,Mitochondria" Yes NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 70: Non-specific - Protein processing" "Cluster 2: Neurons - Nucleosome" "Cluster 66: Non-specific - Mitochondria" "Cluster 88: Proximal tubular cells - Transmembrane transport" 8 Mitochondria "Mitotic chromosome" "HPA071795: , HPA079100: " "unprognostic (1.38e-1)" "unprognostic (5.07e-2)" "unprognostic (5.00e-2)" "unprognostic (2.17e-1)" "unprognostic (7.41e-3)" "unprognostic (2.77e-1)" "unprognostic (5.35e-3)" "unprognostic (6.66e-2)" "unprognostic (2.35e-2)" "unprognostic (2.14e-3)" "unprognostic (1.34e-3)" "unprognostic (1.70e-2)" "unprognostic (1.23e-1)" "unprognostic (1.15e-1)" "unprognostic (3.38e-1)" "unprognostic (3.63e-1)" "unprognostic (3.21e-2)" "unprognostic (2.07e-2)" "unprognostic (1.33e-2)" "unprognostic (3.71e-2)" "unprognostic (4.58e-2)" "unprognostic (7.22e-2)" "unprognostic (3.52e-3)" "unprognostic (3.79e-2)" "unprognostic (2.40e-1)" "unprognostic (1.18e-1)" "unprognostic (4.48e-1)" "unprognostic (9.64e-2)" "unprognostic (2.74e-1)" SELENOP "SELP, SeP, SEPP, SEPP1" ENSG00000250722 "Selenoprotein P" P49908 5 42799880-42887392 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "intestine: 1966.1;liver: 5860.1" "Cell type enhanced" "Detected in many" "Colonocytes: 1222.9;Enterocytes: 6545.4;Hepatocytes: 3668.6;Hofbauer cells: 1839.8;Kupffer cells: 3992.0;Macrophages: 1395.9" "Cell type enhanced" "Detected in many" "oligodendrocyte: 764.7" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 1387.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 182.2" "Liver - Hepatocytes, Spleen - Macrophages, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" HPA036287 Approved Uncertain "Nucleoplasm,Golgi apparatus,Connecting piece" "Secreted to blood" "No annotated function" NA NA 2220000000 1600000000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 30: White matter - Myelination" "Cluster 18: Liver cancer - Metabolism" "Cluster 1: Enterocytes - Absorption and Digestion" 1 "Nucleoplasm, Golgi apparatus" "Connecting piece" "HPA036287: " "unprognostic (5.10e-2)" "unprognostic (5.37e-2)" "unprognostic (3.63e-1)" "unprognostic (5.54e-2)" "unprognostic (2.30e-1)" "unprognostic (7.03e-3)" "unprognostic (1.12e-2)" "unprognostic (1.07e-1)" "unprognostic (1.98e-2)" "validated prognostic favorable (1.06e-10)" "validated prognostic favorable (5.94e-5)" "unprognostic (1.46e-2)" "unprognostic (9.78e-2)" "potential prognostic favorable (2.48e-5)" "unprognostic (9.32e-2)" "unprognostic (9.16e-2)" "unprognostic (1.74e-1)" "unprognostic (1.31e-1)" "unprognostic (3.49e-2)" "unprognostic (6.27e-3)" "unprognostic (8.80e-2)" "unprognostic (8.87e-2)" "unprognostic (5.34e-2)" "unprognostic (4.28e-1)" "unprognostic (3.34e-3)" "unprognostic (4.05e-3)" "unprognostic (6.59e-2)" "unprognostic (2.46e-1)" "unprognostic (1.57e-1)" SELENOS "AD-015, MGC2553, SBBI8, SELS, SEPS1, VIMP" ENSG00000131871 "Selenoprotein S" Q9BQE4 15 101270817-101277500 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 627.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "plasmacytoid DC: 608.2" "Lineage enriched" "Detected in all" 5 "dendritic cells: 608.2" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010025 Approved Enhanced "Endoplasmic reticulum" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 21: Testis - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 67: Plasma cells - Plasma cell differentiation" 16 "Endoplasmic reticulum" "HPA010025: " "unprognostic (3.21e-1)" "unprognostic (1.22e-2)" "unprognostic (1.53e-1)" "unprognostic (3.36e-1)" "unprognostic (7.99e-2)" "unprognostic (7.47e-3)" "unprognostic (2.45e-1)" "potential prognostic unfavorable (4.06e-4)" "unprognostic (3.63e-3)" "potential prognostic favorable (9.45e-6)" "unprognostic (1.85e-1)" "unprognostic (2.76e-1)" "unprognostic (4.44e-2)" "unprognostic (2.40e-1)" "unprognostic (4.69e-2)" "unprognostic (7.76e-2)" "unprognostic (5.41e-1)" "unprognostic (2.16e-2)" "unprognostic (1.61e-1)" "unprognostic (2.37e-3)" "unprognostic (1.12e-1)" "unprognostic (3.28e-1)" "unprognostic (1.81e-1)" "unprognostic (2.54e-2)" "unprognostic (1.30e-1)" "unprognostic (1.16e-1)" "unprognostic (2.80e-1)" "unprognostic (3.00e-2)" "unprognostic (6.80e-2)" SELENOT SELT ENSG00000198843 "Selenoprotein T" P62341 3 150602875-150630436 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 611.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039780 Approved NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 2 "HPA039780: " "unprognostic (3.39e-3)" "unprognostic (1.65e-2)" "unprognostic (2.52e-2)" "unprognostic (1.13e-1)" "unprognostic (4.59e-3)" "unprognostic (3.42e-1)" "unprognostic (3.01e-2)" "unprognostic (3.93e-2)" "unprognostic (5.13e-2)" "potential prognostic favorable (1.93e-8)" "unprognostic (2.04e-1)" "unprognostic (8.53e-2)" "potential prognostic unfavorable (3.87e-4)" "unprognostic (5.21e-2)" "unprognostic (1.56e-1)" "unprognostic (5.30e-2)" "unprognostic (4.66e-2)" "unprognostic (9.58e-2)" "unprognostic (1.05e-3)" "unprognostic (1.24e-2)" "unprognostic (1.69e-1)" "unprognostic (3.21e-1)" "unprognostic (1.10e-1)" "unprognostic (4.49e-1)" "unprognostic (2.10e-1)" "unprognostic (1.12e-1)" "unprognostic (1.00e-1)" "unprognostic (1.90e-1)" "unprognostic (1.66e-2)" SELENOV SELV ENSG00000186838 "Selenoprotein V" P59797 19 39515139-39520675 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "testis: 9.4" "Cell type enriched" "Detected in some" 4 "Late spermatids: 422.5" "Cell type enhanced" "Detected in some" "oligodendrocyte precursor cell: 4.6" "Cancer enhanced" "Detected in single" "Thyroid Carcinoma (TCGA): 1.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Outer root sheath cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA059274 Uncertain NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 6: Non-specific - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 10 "HPA059274: " "unprognostic (1.59e-3)" SELENOW "SELW, SEPW1" ENSG00000178980 "Selenoprotein W" P63302 19 47778677-47784686 "Predicted intracellular proteins" Antioxidant "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 1841.7" "Cell type enhanced" "Detected in all" "Retinal pigment epithelial cells: 1470.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "unprognostic (2.40e-1)" "unprognostic (4.54e-2)" "unprognostic (1.22e-3)" "unprognostic (4.91e-2)" "unprognostic (9.22e-3)" "unprognostic (2.02e-1)" "unprognostic (1.22e-3)" "unprognostic (4.51e-3)" "unprognostic (8.93e-2)" "potential prognostic favorable (4.05e-4)" "unprognostic (6.70e-2)" "unprognostic (1.55e-2)" "unprognostic (2.59e-3)" "potential prognostic favorable (6.03e-4)" "unprognostic (5.57e-2)" "unprognostic (8.90e-2)" "unprognostic (1.38e-2)" "unprognostic (2.08e-1)" "unprognostic (2.26e-1)" "unprognostic (1.60e-1)" "unprognostic (3.92e-1)" "unprognostic (1.95e-1)" "unprognostic (1.81e-1)" "potential prognostic favorable (1.39e-5)" "unprognostic (3.17e-1)" "unprognostic (9.34e-3)" "unprognostic (8.61e-2)" "unprognostic (3.48e-2)" "unprognostic (4.00e-1)" SELL "CD62L, hLHRc, LAM-1, LAM1, Leu-8, LNHR, LSEL, Lyam-1, LYAM1, PLNHR" ENSG00000188404 "Selectin L" P14151 1 169690665-169711702 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 142.1;lymphoid tissue: 216.7" "Cell type enriched" "Detected in many" 4 "Neutrophils: 1390.5" "Cell type enriched" "Detected in some" 5 "leukocyte: 58.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Leukemia: 34.0;lymphoma: 29.2;Myeloma: 15.1" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophils_2, Skeletal muscle - Neutrophils, Spleen - Neutrophils_2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB002144, HPA051972" Enhanced Uncertain Cytosol NA NA 1100000000 "Cluster 35: Neutrophils - Protein binding" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 1 Cytosol "CAB002144: , HPA051972: " "unprognostic (7.76e-2)" "potential prognostic favorable (7.41e-4)" "unprognostic (1.73e-2)" "potential prognostic favorable (9.69e-4)" "unprognostic (3.55e-2)" "unprognostic (1.05e-1)" "unprognostic (4.89e-3)" "unprognostic (1.75e-3)" "unprognostic (1.57e-3)" "unprognostic (4.17e-2)" "unprognostic (4.09e-2)" "unprognostic (2.29e-1)" "potential prognostic unfavorable (5.33e-4)" "potential prognostic favorable (5.49e-4)" "unprognostic (1.47e-2)" "unprognostic (1.62e-1)" "unprognostic (4.86e-2)" "unprognostic (6.18e-2)" "unprognostic (8.00e-2)" "unprognostic (3.70e-3)" "unprognostic (4.41e-2)" "unprognostic (1.36e-1)" "unprognostic (2.50e-1)" "unprognostic (4.78e-2)" "unprognostic (7.24e-2)" "unprognostic (2.68e-1)" "unprognostic (2.97e-2)" "unprognostic (2.05e-2)" "unprognostic (7.77e-3)" "unprognostic (1.43e-1)" "unprognostic (1.85e-1)" SELP "CD62, CD62P, GMP140, GRMP, PADGEM, PSEL" ENSG00000174175 "Selectin P" P16109 1 169588849-169630193 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 5 "Platelets: 579.5" "Cell type enhanced" "Detected in many" "endothelial cell: 5.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "choroid plexus: 8.2" "Immune cell enhanced" "Detected in some" "basophil: 8.2;T-reg: 8.8" "Group enriched" "Detected in many" 7 "granulocytes: 8.2;T-cells: 8.8" "Cancer enriched" "Detected in single" 5 "Leukemia: 2.9" "Breast - Endothelial cells, Colon - Endothelial cells, Minor Salivary Gland - Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB002145, HPA002655, HPA005990" Enhanced NA NA 69000000 "Cluster 35: Neutrophils - Protein binding" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 23: Choroid plexus - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 2 "CAB002145: , HPA002655: , HPA005990: " "unprognostic (1.84e-1)" "unprognostic (4.02e-2)" "unprognostic (2.20e-2)" "unprognostic (2.42e-3)" "unprognostic (3.20e-1)" "unprognostic (1.21e-1)" "potential prognostic favorable (2.91e-4)" "unprognostic (2.72e-1)" "validated prognostic favorable (9.05e-7)" "validated prognostic favorable (7.30e-5)" "unprognostic (3.45e-2)" "potential prognostic favorable (1.11e-4)" "unprognostic (4.47e-3)" "unprognostic (3.29e-2)" "unprognostic (2.89e-2)" "unprognostic (1.30e-1)" "unprognostic (9.44e-3)" "unprognostic (1.79e-1)" "unprognostic (1.27e-1)" "unprognostic (2.96e-1)" "unprognostic (1.42e-1)" "unprognostic (3.93e-2)" "unprognostic (1.58e-2)" "unprognostic (6.80e-2)" "unprognostic (3.87e-2)" SELPLG "CD162, PSGL-1" ENSG00000110876 "Selectin P ligand" Q14242 12 108621895-108633894 "Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 75.0" "Cell type enhanced" "Detected in many" "cDC: 58.9;Hofbauer cells: 58.8;Kupffer cells: 72.8;Macrophages: 49.5;Microglia: 140.9;Monocyte progenitors: 79.3;monocytes: 83.1;Neutrophil progenitors: 59.0;Neutrophils: 449.0;NK-cells: 109.6;pDCs: 193.3;Plasma cells: 66.3;T-cells: 58.8" "Group enriched" "Detected in some" 57 "central nervous system macrophage: 162.9;leukocyte: 71.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 73.4;Myeloma: 231.6" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Minor Salivary Gland - Macrophages, Skeletal muscle - Macrophages, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "CAB002431, HPA011256, HPA069062" Enhanced Approved Vesicles NA NA 14000000 "Cluster 35: Neutrophils - Protein binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 24: Neutrophils - Innate immunity signal integration" 3 Vesicles "CAB002431: , HPA011256: , HPA069062: " "unprognostic (3.56e-2)" "unprognostic (2.51e-2)" "unprognostic (1.81e-1)" "unprognostic (2.09e-1)" "unprognostic (1.18e-1)" "unprognostic (9.64e-2)" "unprognostic (6.03e-2)" "unprognostic (1.06e-1)" "potential prognostic favorable (9.12e-4)" "unprognostic (1.03e-1)" "unprognostic (2.55e-1)" "unprognostic (2.80e-1)" "unprognostic (8.40e-2)" "unprognostic (1.79e-1)" "unprognostic (7.26e-2)" "unprognostic (4.22e-2)" "unprognostic (1.31e-1)" "unprognostic (5.39e-2)" "unprognostic (2.29e-1)" "unprognostic (2.51e-2)" "unprognostic (3.24e-1)" "unprognostic (2.18e-2)" "unprognostic (3.74e-2)" "unprognostic (2.78e-1)" "unprognostic (3.61e-2)" "unprognostic (3.85e-2)" "unprognostic (8.63e-3)" "unprognostic (2.34e-2)" "unprognostic (3.75e-2)" "unprognostic (5.63e-3)" "unprognostic (6.18e-2)" SEM1 "C7orf76, DSS1, ECD, FLJ42280, PSMD15, SHFD1, Shfdg1, SHFM1, SHSF1" ENSG00000127922 "SEM1 26S proteasome subunit" "P60896, Q6ZVN7" 7 96481626-96709880 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 904.3;Syncytiotrophoblasts: 1051.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020429, HPA072648" Uncertain Approved Cytosol NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 70: Non-specific - Protein processing" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 93: Hepatocytes - Bile production & excretion" 109 Cytosol "HPA020429: , HPA072648: " "unprognostic (5.63e-2)" "unprognostic (5.49e-2)" "unprognostic (1.18e-1)" "unprognostic (6.12e-2)" "unprognostic (2.25e-1)" "unprognostic (1.74e-3)" "unprognostic (8.36e-2)" "potential prognostic unfavorable (4.34e-4)" "potential prognostic unfavorable (7.26e-8)" "potential prognostic unfavorable (1.64e-6)" "unprognostic (4.84e-3)" "unprognostic (2.95e-2)" "unprognostic (2.42e-1)" "unprognostic (4.49e-3)" "unprognostic (1.30e-1)" "unprognostic (8.90e-3)" "unprognostic (2.80e-1)" "unprognostic (1.57e-2)" "unprognostic (1.09e-1)" "unprognostic (3.77e-2)" "unprognostic (1.61e-2)" "unprognostic (1.07e-1)" "unprognostic (1.40e-1)" "unprognostic (9.32e-3)" "unprognostic (1.33e-1)" "unprognostic (9.41e-2)" "unprognostic (3.23e-2)" "unprognostic (2.80e-2)" "unprognostic (1.91e-2)" SEMA3A "coll-1, Hsema-I, SEMA1, SEMAD, SemD" ENSG00000075213 "Semaphorin 3A" Q14563 7 83955777-84492724 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 20.9" "Cell type enhanced" "Detected in many" "Adipocytes: 512.7;Conjunctival goblet cells: 341.7;Endometrial secretory cells: 349.1;Gonadotrophs: 383.4;Lymphatic endothelial cells: 768.1;Respiratory basal cells: 192.6;Respiratory secretory cells: 269.6;Retinal ganglion cells: 320.6;Rod photoreceptor cells: 361.9;Smooth muscle cells: 178.6;Somatotrophs: 352.3;Thyrotrophs: 270.9" "Cell type enhanced" "Detected in all" "eccentric medium spiny neuron: 239.1;lower rhombic lip: 307.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "non-classical monocyte: 1.5" "Lineage enriched" "Detected in single" 16 "monocytes: 1.5" "Low cancer specificity" "Detected in many" "Pituitary gland - Thyrotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA029447, HPA052235" Approved Approved Vesicles "Secreted in other tissues" "Developmental protein" NA NA 2200000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 42: Retina - Visual perception" "Cluster 9: Non-specific - Receptor signaling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" Vesicles "HPA029447: , HPA052235: " "unprognostic (1.03e-1)" "unprognostic (2.42e-1)" "potential prognostic unfavorable (1.12e-4)" "unprognostic (3.30e-1)" "unprognostic (3.00e-2)" "unprognostic (8.56e-2)" "unprognostic (1.83e-1)" "unprognostic (1.45e-2)" "unprognostic (4.30e-3)" "unprognostic (3.86e-3)" "unprognostic (3.94e-2)" "unprognostic (1.06e-2)" "unprognostic (3.54e-1)" "unprognostic (2.61e-1)" "unprognostic (1.16e-2)" "unprognostic (4.16e-3)" "unprognostic (4.02e-1)" "unprognostic (1.40e-2)" "unprognostic (2.41e-1)" "unprognostic (1.48e-1)" "unprognostic (1.59e-1)" "unprognostic (4.21e-2)" SEMA3B "LUCA-1, SemA, sema5, SEMAA, semaV" ENSG00000012171 "Semaphorin 3B" Q13214 3 50267558-50277546 "Cancer-related genes, Essential proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 162.8;brain: 159.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 260.6;Endometrial luminal cells: 137.6;Endometrial secretory cells: 216.2;Enterocytes: 378.9;Fallopian secretory cells: 137.4;Foveolar cells: 133.7;Oligodendrocytes: 203.1;Podocytes: 136.0;Retinal pigment epithelial cells: 127.9;Schwann cells: 365.3;Syncytiotrophoblasts: 153.7" "Cell type enhanced" "Detected in many" "astrocyte: 102.4;committed oligodendrocyte precursor: 85.7;oligodendrocyte: 247.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 82.3" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal cortex cells, Colon - Enteric glia cells, Lung - Alveolar cells type 1, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 5 "spinal cord: 36.8" HPA030651 Uncertain "Secreted in other tissues" "Developmental protein" NA NA 500000 "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 51: Secretory epithelial cells - Mixed function" "HPA030651: " "potential prognostic favorable (8.02e-5)" "unprognostic (1.56e-3)" "unprognostic (5.04e-3)" "unprognostic (2.17e-2)" "unprognostic (2.49e-1)" "unprognostic (1.20e-2)" "unprognostic (9.26e-2)" "unprognostic (9.76e-2)" "unprognostic (2.46e-1)" "unprognostic (2.47e-2)" "unprognostic (4.22e-2)" "unprognostic (2.22e-2)" "potential prognostic unfavorable (6.68e-5)" "unprognostic (2.20e-1)" "unprognostic (6.48e-2)" "unprognostic (2.07e-1)" "unprognostic (6.67e-2)" "unprognostic (1.35e-3)" "unprognostic (4.77e-2)" "unprognostic (6.01e-2)" "unprognostic (4.06e-2)" "unprognostic (7.35e-3)" "unprognostic (2.09e-2)" "unprognostic (3.10e-1)" "unprognostic (3.26e-2)" "unprognostic (2.01e-1)" "unprognostic (2.14e-2)" "unprognostic (1.88e-1)" "unprognostic (1.52e-1)" "unprognostic (1.41e-3)" "unprognostic (2.78e-1)" SEMA3C "SEMAE, SemE" ENSG00000075223 "Semaphorin 3C" Q99985 7 80742538-80922359 "Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Epididymal basal cells: 741.8;Epididymal clear cells: 502.2;Fibro-adipogenic progenitors: 557.4;Melanocytes: 719.7;Mesothelial cells: 1101.0;Renal collecting duct intercalated cells: 659.2;Respiratory ionocytes: 1008.4;Schwann cells: 893.4;Sertoli cells: 460.2;Urothelial cells: 931.3" "Cell type enhanced" "Detected in all" "midbrain-derived inhibitory: 782.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 9 "basophil: 49.7" "Lineage enriched" "Detected in many" 9 "granulocytes: 49.7" "Low cancer specificity" "Detected in all" "Pituitary gland - Fibroblasts, Spleen - Fibroblasts_1, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA042418 Approved "Golgi apparatus,Plasma membrane,Cytosol" "Secreted in other tissues" "Developmental protein" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 75: Ovary - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 69: Urothelial cells - Basic cellular functions" 14 "Golgi apparatus, Cytosol" "Plasma membrane" "HPA042418: " "unprognostic (1.81e-2)" "unprognostic (7.38e-2)" "unprognostic (3.12e-1)" "unprognostic (1.13e-3)" "unprognostic (7.66e-2)" "unprognostic (7.09e-2)" "unprognostic (3.12e-2)" "unprognostic (8.15e-3)" "potential prognostic unfavorable (5.43e-4)" "unprognostic (2.03e-3)" "unprognostic (1.95e-3)" "potential prognostic unfavorable (1.12e-4)" "unprognostic (3.84e-2)" "unprognostic (7.18e-2)" "potential prognostic unfavorable (2.83e-4)" "unprognostic (1.92e-2)" "unprognostic (6.21e-2)" "unprognostic (3.27e-3)" "unprognostic (1.42e-1)" "unprognostic (1.67e-3)" "potential prognostic unfavorable (1.11e-4)" "unprognostic (1.11e-2)" "unprognostic (5.40e-2)" "unprognostic (1.91e-1)" "unprognostic (1.38e-2)" "unprognostic (3.06e-2)" "unprognostic (5.72e-3)" "unprognostic (1.65e-1)" "unprognostic (1.15e-2)" "unprognostic (2.02e-1)" SEMA3D "coll-2, Sema-Z2" ENSG00000153993 "Semaphorin 3D" O95025 7 84995553-85187056 "Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "lymphoid tissue: 38.1;thyroid gland: 33.1" "Cell type enhanced" "Detected in many" "Early spermatids: 213.3;Ependymal cells: 106.8;Fibro-adipogenic progenitors: 80.7;Leydig cells: 253.1;Lymphatic endothelial cells: 476.8;Mesothelial cells: 207.6;Peritubular myoid cells: 190.4;Prostatic glandular cells: 244.6" "Cell type enhanced" "Detected in many" "hippocampal CA1-3: 127.1" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 7.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 26.3;Sarcoma: 55.3" "Breast - Breast myoepithelial cells, Heart muscle - Smooth muscle cells, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011183, HPA037522" Uncertain Approved Vesicles "Secreted in other tissues" "Developmental protein" NA NA 70000 "Cluster 66: Lymphoid tissue - Immune response" "Cluster 27: Non-specific - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" Vesicles "HPA011183: , HPA037522: " "unprognostic (2.05e-1)" "unprognostic (4.78e-2)" "unprognostic (1.39e-1)" "unprognostic (3.08e-1)" "unprognostic (2.24e-1)" "unprognostic (1.57e-3)" "unprognostic (2.40e-1)" "potential prognostic favorable (9.04e-8)" "unprognostic (2.14e-1)" "unprognostic (1.87e-1)" "unprognostic (2.25e-2)" "unprognostic (3.96e-3)" "unprognostic (2.89e-1)" "unprognostic (2.23e-2)" "potential prognostic unfavorable (4.45e-6)" "unprognostic (2.13e-1)" "unprognostic (1.29e-1)" "unprognostic (1.85e-1)" "unprognostic (2.33e-1)" "unprognostic (5.09e-3)" "unprognostic (1.88e-1)" "unprognostic (3.53e-3)" "unprognostic (1.32e-1)" SEMA3E "coll-5, KIAA0331, M-SemaK, SEMAH" ENSG00000170381 "Semaphorin 3E" O15041 7 83363238-83649139 "Human disease related genes, Predicted secreted proteins" "Angiogenesis, Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 164.8;Brain inhibitory neurons: 71.1;Cholangiocytes: 111.0;Foveolar cells: 67.1;Medullary thymic epithelial cells: 148.8;Müller glia: 103.5;Oligodendrocyte progenitor cells: 244.5;Oocytes: 78.3;Pancreatic islet cells: 105.4;Respiratory ciliated cells: 76.4;Retinal bipolar cells: 206.9;Smooth muscle cells: 94.7" "Cell type enhanced" "Detected in all" "deep-layer corticothalamic and 6b: 510.1;deep-layer near-projecting: 506.8;oligodendrocyte precursor cell: 469.9" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 7.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "thyroid cancer: 13.9" "Liver - Cholangiocytes, Lung - Alveolar cells type 1, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA029419, HPA063804" Uncertain Approved Nucleoplasm,Vesicles "Secreted in other tissues" "Developmental protein" NA NA "Cluster 42: Retina - Visual perception" "Cluster 38: Sub-cortical - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 1 Vesicles Nucleoplasm "HPA029419: , HPA063804: " "unprognostic (1.32e-1)" "unprognostic (6.71e-2)" "unprognostic (5.60e-2)" "unprognostic (2.71e-1)" "unprognostic (5.09e-3)" "unprognostic (3.17e-2)" "unprognostic (1.34e-1)" "unprognostic (8.30e-2)" "unprognostic (1.22e-2)" "unprognostic (8.92e-2)" "unprognostic (1.47e-2)" "unprognostic (1.71e-1)" "potential prognostic unfavorable (7.41e-4)" "unprognostic (1.59e-1)" "unprognostic (6.16e-3)" "unprognostic (4.95e-2)" SEMA3F "Sema4, SEMAK" ENSG00000001617 "Semaphorin 3F" Q13275 3 50155045-50189075 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 96.2" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 45.1;Esophageal apical cells: 97.3;Esophageal suprabasal cells: 72.8;Papillary tip epithelial cells: 70.6;Prostatic hillock cells: 123.0;Suprabasal keratinocytes: 56.2;Vascular endothelial cells: 49.1" "Cell type enhanced" "Detected in many" "endothelial cell: 28.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 84.1" "Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Pancreas - Endothelial cells, Pituitary gland - Endothelial cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA035008 Approved "Secreted to blood" "Developmental protein" NA NA 1700000 5500000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "HPA035008: " "unprognostic (7.06e-2)" "unprognostic (2.85e-1)" "unprognostic (1.13e-1)" "unprognostic (1.32e-1)" "unprognostic (1.99e-1)" "unprognostic (2.11e-2)" "potential prognostic unfavorable (8.87e-4)" "unprognostic (1.99e-2)" "unprognostic (2.11e-1)" "unprognostic (2.39e-1)" "potential prognostic favorable (7.70e-7)" "unprognostic (3.53e-3)" "unprognostic (2.70e-1)" "potential prognostic unfavorable (5.63e-4)" "unprognostic (2.86e-2)" "unprognostic (3.23e-2)" "unprognostic (7.06e-3)" "unprognostic (2.15e-1)" "unprognostic (2.56e-1)" "unprognostic (8.54e-2)" "unprognostic (2.47e-1)" "unprognostic (6.67e-3)" "unprognostic (4.58e-2)" "unprognostic (8.47e-2)" "unprognostic (5.01e-2)" "unprognostic (3.43e-1)" "unprognostic (4.79e-2)" "unprognostic (1.85e-1)" "unprognostic (1.26e-1)" "unprognostic (1.91e-2)" "unprognostic (1.15e-1)" SEMA3G "FLJ00014, sem2" ENSG00000010319 "Semaphorin 3G" Q9NS98 3 52433035-52445103 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 67.3;breast: 55.7" "Cell type enhanced" "Detected in some" "Adipocytes: 14.5;Endometrial luminal cells: 8.9;Enterocytes: 12.4;Myonuclei: 8.7;Podocytes: 54.5;Retinal amacrine cells: 8.1;Schwann cells: 25.4;Syncytiotrophoblasts: 8.8;Vascular endothelial cells: 45.3" "Cell type enriched" "Detected in some" 4 "endothelial cell: 98.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 15 "T-reg: 1.4" "Lineage enriched" "Detected in single" 15 "T-cells: 1.4" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Adipocytes (Subcutaneous), Colon - Endothelial cells, Heart muscle - Endothelial cells, Prostate - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001761 Uncertain "Secreted to blood" "Developmental protein" NA NA 3500000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 25: Non-specific - Transcription" "Cluster 18: Liver cancer - Metabolism" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 1 "HPA001761: " "unprognostic (5.73e-3)" "unprognostic (3.03e-2)" "unprognostic (4.06e-2)" "unprognostic (6.73e-2)" "unprognostic (1.48e-1)" "unprognostic (5.96e-2)" "unprognostic (9.14e-2)" "unprognostic (1.69e-1)" "unprognostic (1.37e-2)" "unprognostic (2.99e-1)" "validated prognostic favorable (5.69e-12)" "validated prognostic favorable (7.13e-5)" "unprognostic (1.73e-2)" "potential prognostic favorable (5.78e-4)" "unprognostic (9.54e-2)" "unprognostic (8.18e-3)" "unprognostic (5.22e-2)" "unprognostic (7.83e-2)" "unprognostic (1.02e-2)" "unprognostic (3.89e-2)" "unprognostic (2.50e-1)" "potential prognostic favorable (5.92e-4)" "unprognostic (4.42e-2)" "unprognostic (2.74e-1)" "unprognostic (1.33e-1)" "unprognostic (9.02e-2)" "unprognostic (1.96e-1)" "unprognostic (1.27e-1)" "unprognostic (1.22e-1)" "unprognostic (1.33e-1)" "unprognostic (4.44e-2)" SEMA4A "CORD10, FLJ12287, SEMAB, SemB" ENSG00000196189 "Semaphorin 4A" Q9H3S1 1 156147366-156177752 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Angiogenesis, Differentiation, Immunity, Neurogenesis" "Developmental protein" "Cone-rod dystrophy, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 48.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 516.3;Epicardial cells: 247.9;Mast cells: 391.9;Salivary basal cells: 646.3;Salivary myoepithelial cells: 858.6;Transitional alveolar cells: 309.3" "Cell type enhanced" "Detected in many" "deep-layer corticothalamic and 6b: 57.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 124.0;eosinophil: 120.5;intermediate monocyte: 132.8;myeloid DC: 183.2;neutrophil: 211.4;non-classical monocyte: 76.6" "Group enriched" "Detected in all" 13 "dendritic cells: 183.2;granulocytes: 211.4;monocytes: 132.8" "Cancer enhanced" "Detected in many" "lymphoma: 47.3;Myeloma: 105.7" "Adipose visceral - Neutrophils, Spleen - Neutrophils_2, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069136 Supported NA NA 3000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 58: Skin - Keratinization" "Cluster 51: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 103: Non-specific - Basic cellular processes" 1 "HPA069136: " "unprognostic (9.91e-2)" "unprognostic (1.26e-1)" "unprognostic (8.63e-2)" "unprognostic (1.77e-1)" "unprognostic (3.04e-1)" "unprognostic (3.75e-2)" "unprognostic (1.33e-1)" "unprognostic (1.10e-1)" "unprognostic (1.55e-2)" "unprognostic (1.55e-1)" "unprognostic (3.57e-2)" "unprognostic (2.13e-1)" "unprognostic (2.65e-1)" "unprognostic (1.24e-1)" "unprognostic (5.20e-2)" "unprognostic (1.45e-3)" "unprognostic (9.85e-2)" "unprognostic (3.05e-2)" "unprognostic (2.85e-2)" "unprognostic (1.68e-1)" "unprognostic (1.01e-1)" "unprognostic (4.63e-2)" "unprognostic (1.56e-2)" "unprognostic (3.85e-1)" "unprognostic (1.09e-1)" "unprognostic (6.74e-2)" "unprognostic (1.09e-1)" "unprognostic (3.36e-2)" "unprognostic (3.10e-1)" "unprognostic (1.53e-2)" "unprognostic (1.35e-1)" SEMA4B "KIAA1745, MGC131831, SEMAC, SemC" ENSG00000185033 "Semaphorin 4B" Q9NPR2 15 90160604-90229679 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 119.6" "Cell type enhanced" "Detected in many" "Esophageal suprabasal cells: 277.5;Ocular epithelial cells: 245.4;Prostatic hillock cells: 284.8;Urothelial cells: 418.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 17.0;naive B-cell: 15.0;neutrophil: 5.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Prostate - Urothelial cells, Spleen - Fibroblasts_2, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013372 Approved Approved "Nucleoplasm,Vesicles,Cell Junctions" NA NA 67000000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 69: Urothelial cells - Basic cellular functions" "Cell Junctions" "Nucleoplasm, Vesicles" "HPA013372: " "unprognostic (3.36e-1)" "unprognostic (2.34e-1)" "unprognostic (2.66e-2)" "unprognostic (1.83e-3)" "unprognostic (1.98e-2)" "unprognostic (1.59e-2)" "unprognostic (1.26e-1)" "unprognostic (2.23e-1)" "unprognostic (2.05e-2)" "unprognostic (1.16e-1)" "unprognostic (3.40e-3)" "unprognostic (1.49e-2)" "unprognostic (4.22e-3)" "unprognostic (1.09e-3)" "potential prognostic unfavorable (5.35e-4)" "validated prognostic unfavorable (2.10e-4)" "validated prognostic unfavorable (1.30e-7)" "unprognostic (5.03e-2)" "unprognostic (1.13e-1)" "unprognostic (1.61e-1)" "unprognostic (3.23e-2)" "unprognostic (1.66e-3)" "unprognostic (4.19e-3)" "unprognostic (6.40e-2)" "unprognostic (6.72e-2)" "unprognostic (1.99e-2)" "unprognostic (1.76e-1)" "unprognostic (1.21e-1)" "unprognostic (2.79e-1)" "unprognostic (1.80e-2)" "unprognostic (5.19e-2)" SEMA4C "Semacl1, Semaf, SEMAI" ENSG00000168758 "Semaphorin 4C" Q9C0C4 2 96859718-96870757 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 51.2;Extravillous trophoblasts: 201.3;Migrating cytotrophoblasts: 69.7;Syncytiotrophoblasts: 44.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Endothelial cells, Kidney - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011090 Approved NA NA 540000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 75: Ovary - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 34: Testis cancer - Unknown function" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 38 "HPA011090: " "unprognostic (2.46e-2)" "unprognostic (9.91e-3)" "unprognostic (5.79e-2)" "unprognostic (4.44e-3)" "unprognostic (2.17e-3)" "unprognostic (3.72e-1)" "unprognostic (1.12e-1)" "unprognostic (9.08e-2)" "unprognostic (5.81e-2)" "unprognostic (8.49e-2)" "potential prognostic favorable (2.39e-4)" "unprognostic (2.24e-3)" "unprognostic (3.50e-3)" "unprognostic (8.58e-3)" "unprognostic (1.57e-2)" "unprognostic (2.00e-1)" "potential prognostic unfavorable (7.23e-4)" "unprognostic (2.68e-2)" "unprognostic (7.93e-2)" "unprognostic (1.36e-2)" "unprognostic (2.63e-1)" "unprognostic (1.25e-1)" "unprognostic (7.29e-2)" "unprognostic (9.16e-2)" "unprognostic (1.41e-1)" "unprognostic (5.17e-3)" "unprognostic (6.92e-2)" "unprognostic (2.83e-2)" "unprognostic (3.28e-1)" "unprognostic (4.85e-2)" "unprognostic (4.68e-2)" SEMA4D "C9orf164, CD100, coll-4, FLJ39737, SEMAJ" ENSG00000187764 "Semaphorin 4D" Q92854 9 89360787-89498130 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 325.7" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 269.9;Microglia: 235.2;Neutrophils: 756.5;Oligodendrocytes: 483.4;Platelets: 219.5;T-cells: 239.3" "Group enriched" "Detected in all" 4 "central nervous system macrophage: 286.4;committed oligodendrocyte precursor: 512.8;leukocyte: 361.0;oligodendrocyte: 549.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Leukemia: 47.6" "Colon - T-cells, Skin - Keratinocyte (granular), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015662, HPA023277" Approved Supported "Nucleoplasm,Vesicles,Plasma membrane,Primary cilium transition zone,Centrosome,Basal body" NA NA 2800000 "Cluster 21: Neutrophils - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 59: Leukemia - T-cell receptor" "Cluster 24: Neutrophils - Innate immunity signal integration" 7 "Plasma membrane" "Nucleoplasm, Vesicles, Primary cilium transition zone, Centrosome, Basal body" "HPA015662: , HPA023277: " "unprognostic (3.04e-2)" "unprognostic (1.12e-1)" "unprognostic (5.62e-2)" "unprognostic (2.60e-1)" "unprognostic (7.72e-2)" "unprognostic (1.91e-1)" "unprognostic (2.01e-1)" "unprognostic (1.12e-1)" "unprognostic (1.88e-2)" "unprognostic (2.51e-2)" "potential prognostic favorable (7.28e-5)" "unprognostic (1.15e-2)" "unprognostic (6.21e-2)" "unprognostic (1.20e-1)" "unprognostic (3.53e-2)" "unprognostic (2.02e-1)" "unprognostic (3.13e-2)" "unprognostic (2.13e-2)" "unprognostic (1.35e-2)" "unprognostic (2.82e-1)" "unprognostic (5.16e-2)" "unprognostic (4.96e-2)" "unprognostic (2.94e-2)" "unprognostic (6.56e-2)" "unprognostic (6.53e-2)" "unprognostic (4.42e-3)" "unprognostic (2.93e-2)" "unprognostic (6.61e-2)" "unprognostic (1.05e-1)" "unprognostic (4.68e-1)" "unprognostic (4.19e-2)" SEMA4F "SEMAM, SEMAW" ENSG00000135622 "Ssemaphorin 4F" O95754 2 74654228-74683853 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 25.1;Brain inhibitory neurons: 19.1;Gonadotrophs: 18.8;Other brain neurons: 22.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064095 Approved NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 27: Cerebellum - Synaptic function" "Cluster 51: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" 2 "HPA064095: " "unprognostic (1.63e-1)" "unprognostic (5.79e-2)" "unprognostic (1.49e-2)" "unprognostic (5.12e-3)" "unprognostic (2.87e-1)" "unprognostic (1.85e-2)" "unprognostic (9.29e-3)" "unprognostic (4.87e-2)" "unprognostic (1.26e-2)" "potential prognostic unfavorable (7.15e-5)" "potential prognostic unfavorable (3.33e-4)" "unprognostic (5.26e-2)" "unprognostic (1.26e-1)" "unprognostic (1.63e-3)" "unprognostic (7.71e-2)" "unprognostic (3.45e-1)" "unprognostic (2.31e-1)" "unprognostic (2.92e-2)" "unprognostic (1.99e-1)" "unprognostic (8.72e-2)" "unprognostic (4.90e-2)" "unprognostic (4.19e-2)" "potential prognostic unfavorable (6.51e-4)" "unprognostic (4.13e-1)" "unprognostic (2.05e-1)" "unprognostic (1.03e-1)" "unprognostic (2.62e-2)" "unprognostic (3.77e-3)" "unprognostic (2.73e-1)" "unprognostic (6.13e-2)" "unprognostic (1.02e-2)" SEMA4G "FLJ20590, KIAA1619" ENSG00000095539 "Semaphorin 4G" Q9NTN9 10 100969504-100985871 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 26.1" "Cell type enhanced" "Detected in many" "Colonocytes: 73.7;Enteric stem cells: 30.0;Enteric transient amplifying cells: 35.8;Enterocytes: 51.4;Goblet cells: 36.9;Hepatocytes: 72.4;Paneth cells: 34.8;Prostatic glandular cells: 28.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038362, HPA077752" Uncertain Uncertain "Vesicles,Lipid droplets" "Intracellular and membrane" "Developmental protein" NA NA 1000000 "Cluster 77: Intestine - Digestion" "Cluster 38: Sub-cortical - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 4 "Vesicles, Lipid droplets" "HPA038362: , HPA077752: " "unprognostic (2.17e-1)" "potential prognostic unfavorable (2.28e-4)" "unprognostic (4.29e-1)" "unprognostic (3.22e-2)" "unprognostic (3.00e-1)" "unprognostic (1.90e-1)" "unprognostic (3.15e-1)" "unprognostic (1.96e-3)" "unprognostic (8.64e-2)" "unprognostic (2.08e-1)" "potential prognostic favorable (2.91e-4)" "unprognostic (1.99e-2)" "unprognostic (2.49e-2)" "unprognostic (2.99e-1)" "unprognostic (2.11e-1)" "unprognostic (4.00e-3)" "unprognostic (1.26e-1)" "unprognostic (1.24e-1)" "unprognostic (6.05e-2)" "unprognostic (7.06e-2)" "unprognostic (2.80e-1)" "unprognostic (3.12e-3)" "unprognostic (2.49e-2)" "unprognostic (4.58e-1)" "unprognostic (7.00e-2)" "unprognostic (2.69e-2)" "unprognostic (1.53e-1)" "unprognostic (2.73e-2)" "unprognostic (1.25e-1)" "unprognostic (1.31e-1)" "unprognostic (1.34e-1)" SEMA5A "SEMAF, semF" ENSG00000112902 "Semaphorin 5A" Q13591 5 9035033-9546075 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 738.8;Mesothelial cells: 445.8;Oligodendrocyte progenitor cells: 1407.8;Oligodendrocytes: 526.2;Podocytes: 2208.0;Respiratory basal cells: 484.1;Retinal horizontal cells: 1041.8;Urothelial cells: 591.2" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 2167.0;hippocampal dentate gyrus: 1239.8;oligodendrocyte precursor cell: 1597.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 12 "plasmacytoid DC: 2.9" "Lineage enriched" "Detected in single" 12 "dendritic cells: 2.9" "Cancer enhanced" "Detected in many" "skin cancer: 21.8" "Kidney - Podocytes, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004632 Approved NA NA 11000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 72: Kidney - Transmembrane transport" "Cluster 29: Forebrain - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" "HPA004632: " "unprognostic (9.65e-3)" "unprognostic (1.46e-1)" "unprognostic (3.45e-1)" "unprognostic (8.36e-2)" "unprognostic (8.45e-2)" "unprognostic (4.53e-2)" "unprognostic (3.35e-1)" "unprognostic (2.35e-3)" "potential prognostic favorable (1.71e-4)" "unprognostic (3.93e-2)" "validated prognostic favorable (2.30e-8)" "validated prognostic favorable (1.68e-4)" "unprognostic (2.16e-3)" "unprognostic (1.08e-1)" "unprognostic (9.83e-2)" "unprognostic (2.00e-2)" "unprognostic (1.06e-1)" "unprognostic (5.84e-2)" "unprognostic (3.85e-1)" "unprognostic (1.91e-1)" "unprognostic (4.36e-3)" "unprognostic (1.02e-2)" "unprognostic (2.41e-1)" "unprognostic (1.08e-1)" "unprognostic (1.36e-1)" "unprognostic (1.10e-1)" "unprognostic (1.23e-1)" "unprognostic (2.98e-2)" "unprognostic (1.70e-1)" "unprognostic (2.81e-2)" "unprognostic (4.95e-1)" SEMA5B "FLJ10372, KIAA1445, SEMAG, SemG" ENSG00000082684 "Semaphorin 5B" Q9P283 3 122909082-123028605 "Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 14.1" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 34.8;Brain inhibitory neurons: 32.1;Cardiomyocytes: 28.4;Ependymal cells: 37.4;Müller glia: 53.8;Oligodendrocyte progenitor cells: 79.2;Oligodendrocytes: 67.5;Pericytes: 36.0;Retinal bipolar cells: 28.7;Vascular smooth muscle cells: 19.5" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 302.0;eccentric medium spiny neuron: 277.9" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 90.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 13.1;Kidney cancer: 23.3" "Liver - Hepatic stellate cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA066548 Enhanced Supported Cytosol NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" Cytosol "HPA066548: " "unprognostic (2.88e-1)" "unprognostic (1.11e-2)" "unprognostic (7.60e-2)" "unprognostic (2.30e-2)" "unprognostic (6.53e-2)" "unprognostic (8.50e-2)" "unprognostic (1.45e-2)" "unprognostic (2.03e-1)" "unprognostic (2.42e-1)" "potential prognostic favorable (1.80e-5)" "unprognostic (1.11e-1)" "unprognostic (1.54e-1)" "unprognostic (3.95e-2)" "unprognostic (1.29e-1)" "unprognostic (1.07e-3)" "unprognostic (1.34e-2)" "unprognostic (2.36e-1)" "unprognostic (1.02e-1)" "unprognostic (6.24e-2)" "unprognostic (8.18e-2)" "unprognostic (5.69e-2)" "unprognostic (2.54e-2)" "unprognostic (1.19e-3)" "unprognostic (1.30e-1)" "unprognostic (3.62e-2)" "unprognostic (1.35e-2)" SEMA6A "HT018, KIAA1368, SEMA, SEMA6A1, SEMAQ" ENSG00000092421 "Semaphorin 6A" Q9H2E6 5 116443555-116574823 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 60.3;brain: 54.1" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 800.9;Bergmann glia: 250.5;Cardiomyocytes: 525.3;Colonocytes: 257.7;Cytotrophoblasts: 328.2;Epicardial cells: 336.6;Lymphatic endothelial cells: 408.6;Oligodendrocytes: 387.0;Retinal horizontal cells: 280.5;Syncytiotrophoblasts: 835.3" "Cell type enhanced" "Detected in all" "endothelial cell: 403.6;oligodendrocyte: 521.9" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 81.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "testis cancer: 203.7" "Liver - Sinusoid Endothelial cells, Spleen - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031264, HPA031265, HPA031267" Approved Approved "Nucleoplasm,Nuclear bodies,Intermediate filaments" NA NA 670000 "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 1 Nucleoplasm "Nuclear bodies, Intermediate filaments" "HPA031264: , HPA031265: , HPA031267: " "unprognostic (2.18e-1)" "unprognostic (6.53e-2)" "unprognostic (7.82e-3)" "unprognostic (6.55e-2)" "unprognostic (4.26e-3)" "unprognostic (4.30e-2)" "unprognostic (2.18e-2)" "unprognostic (9.72e-2)" "unprognostic (2.81e-1)" "unprognostic (7.81e-2)" "validated prognostic favorable (1.03e-4)" "validated prognostic favorable (2.00e-4)" "unprognostic (1.02e-1)" "potential prognostic unfavorable (1.94e-4)" "unprognostic (4.00e-2)" "unprognostic (3.40e-1)" "unprognostic (2.37e-1)" "unprognostic (5.45e-2)" "unprognostic (1.10e-2)" "unprognostic (8.69e-2)" "unprognostic (4.49e-2)" "unprognostic (1.07e-2)" "unprognostic (9.18e-2)" "unprognostic (6.66e-2)" "unprognostic (6.27e-2)" "unprognostic (2.92e-1)" "unprognostic (2.06e-1)" "unprognostic (3.65e-3)" "unprognostic (2.27e-1)" "unprognostic (5.36e-3)" "unprognostic (1.33e-2)" SEMA6B "SEM-SEMA-Z, SEMA-VIB, SEMAN, semaZ" ENSG00000167680 "Semaphorin 6B" Q9H3T3 19 4542593-4581776 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 71.3" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 27.7;Brain inhibitory neurons: 29.2;cDC: 44.6;Macrophages: 57.9;monocytes: 174.6;Neutrophils: 55.7;Oligodendrocyte progenitor cells: 27.3;Retinal amacrine cells: 57.6;Retinal ganglion cells: 34.8;Retinal horizontal cells: 30.1;Vascular endothelial cells: 84.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 51.5" "Breast - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025157, HPA055778, HPA058523" Enhanced NA NA 8100000 "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 27 "CAB025157: , HPA055778: , HPA058523: " "unprognostic (3.60e-3)" "unprognostic (3.41e-1)" "unprognostic (1.07e-1)" "unprognostic (9.41e-2)" "unprognostic (5.50e-2)" "unprognostic (6.20e-2)" "unprognostic (6.02e-2)" "unprognostic (1.55e-2)" "unprognostic (6.26e-2)" "unprognostic (1.65e-1)" "unprognostic (1.24e-3)" "unprognostic (4.37e-2)" "potential prognostic unfavorable (1.36e-4)" "unprognostic (5.74e-2)" "unprognostic (7.45e-2)" "unprognostic (5.27e-2)" "unprognostic (2.83e-2)" "unprognostic (1.10e-2)" "unprognostic (2.90e-1)" "unprognostic (1.96e-1)" "unprognostic (2.33e-1)" "unprognostic (1.77e-2)" "unprognostic (1.83e-2)" "unprognostic (7.12e-2)" "unprognostic (2.62e-2)" "unprognostic (2.79e-1)" "unprognostic (8.85e-2)" "unprognostic (3.94e-2)" "unprognostic (1.96e-1)" "potential prognostic unfavorable (2.44e-5)" "unprognostic (5.79e-3)" SEMA6C "KIAA1869, Sema-Y" ENSG00000143434 "Semaphorin 6C" Q9H3T2 1 151131685-151146631 "Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 262.9;tongue: 85.2" "Cell type enhanced" "Detected in many" "Granulosa cells: 40.5;Myonuclei: 180.8;Proximal tubule cells: 42.8;Sertoli cells: 74.5;Thymic myoid cells: 51.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Minor Salivary Gland - Endothelial cells, Skeletal muscle - Skeletal myocytes, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 6000000 "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 15: Non-specific - Transcription" "Cluster 6: Leukemia - Signal transduction" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" "unprognostic (3.72e-2)" "unprognostic (1.96e-1)" "unprognostic (7.90e-3)" "unprognostic (8.98e-2)" "unprognostic (1.16e-2)" "unprognostic (1.61e-1)" "unprognostic (1.12e-1)" "potential prognostic favorable (1.61e-4)" "unprognostic (5.81e-2)" "unprognostic (1.01e-1)" "unprognostic (3.18e-3)" "potential prognostic favorable (2.30e-4)" "unprognostic (3.65e-2)" "unprognostic (7.69e-3)" "unprognostic (1.15e-1)" "unprognostic (2.45e-2)" "unprognostic (1.66e-2)" "unprognostic (8.14e-2)" "potential prognostic favorable (9.14e-4)" "unprognostic (2.04e-2)" "unprognostic (1.80e-1)" "potential prognostic favorable (7.46e-5)" "unprognostic (1.92e-1)" "unprognostic (4.92e-3)" "unprognostic (5.27e-1)" "unprognostic (1.95e-3)" "unprognostic (1.19e-2)" "unprognostic (3.29e-2)" "unprognostic (1.91e-1)" "unprognostic (1.84e-2)" "unprognostic (3.00e-3)" SEMA6D "FLJ11598, KIAA1479" ENSG00000137872 "Semaphorin 6D" Q8NFY4 15 47184101-47774228 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 36.3;placenta: 40.4" "Cell type enhanced" "Detected in many" "Bergmann glia: 1265.4;Brain inhibitory neurons: 502.1;Cone photoreceptor cells: 888.1;Cytotrophoblasts: 529.5;Distal convoluted tubule cells: 246.2;Migrating cytotrophoblasts: 242.8;Neuroendocrine cells: 235.0;Other brain neurons: 350.1" "Cell type enhanced" "Detected in all" "Bergmann glia: 1207.6;eccentric medium spiny neuron: 1517.4;LAMP5-LHX6 and Chandelier: 1124.3" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 21.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 13.0" "Adipose visceral - Mesothelial cells, Kidney - Ascending Loop of Henle cells, Liver - Hepatic stellate cells, Minor Salivary Gland - Fibroblasts, Skeletal muscle - Skeletal myocytes, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043109 Approved "Golgi apparatus,Plasma membrane" "Intracellular and membrane" "Developmental protein" NA NA 920000 "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 1: Neuronal - Visual perception" "Cluster 35: Neurons - Synaptic function & neurogenesis" "Plasma membrane" "Golgi apparatus" "HPA043109: " "unprognostic (2.54e-2)" "unprognostic (3.72e-1)" "unprognostic (1.77e-1)" "unprognostic (1.00e-1)" "unprognostic (2.59e-2)" "unprognostic (1.78e-1)" "unprognostic (7.21e-2)" "unprognostic (1.17e-2)" "unprognostic (4.64e-2)" "unprognostic (8.87e-2)" "potential prognostic favorable (1.56e-4)" "unprognostic (2.22e-3)" "unprognostic (5.92e-3)" "potential prognostic favorable (8.48e-4)" "unprognostic (7.66e-3)" "unprognostic (1.81e-2)" "unprognostic (1.22e-1)" "potential prognostic favorable (7.22e-4)" "unprognostic (2.71e-1)" "unprognostic (2.02e-2)" "unprognostic (3.28e-3)" "unprognostic (6.23e-2)" "unprognostic (4.04e-3)" "unprognostic (8.15e-2)" "unprognostic (6.45e-2)" "potential prognostic unfavorable (5.64e-5)" "unprognostic (2.17e-2)" "unprognostic (2.28e-1)" "potential prognostic unfavorable (8.35e-4)" "unprognostic (3.51e-3)" SEMA7A "CD108, H-Sema-L, SEMAL" ENSG00000138623 "Semaphorin 7A (John Milton Hagen blood group)" O75326 15 74409289-74433958 "Blood group antigen proteins, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Differentiation, Inflammatory response, Neurogenesis" "Developmental protein" "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 61.8;lymphoid tissue: 55.3;retina: 32.1" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 11.7;Brain inhibitory neurons: 3.4;Megakaryocytes: 6.2;Microglia: 10.6;Oligodendrocyte progenitor cells: 4.7;Oligodendrocytes: 18.1;Papillary tip epithelial cells: 4.6;Podocytes: 3.4;Tuft cells: 11.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 1.8;eosinophil: 3.1" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.1" "Low cancer specificity" "Detected in all" "Pituitary gland - Gonadotropes, Skin - Keratinocyte (granular), Stomach - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008210, HPA042273" Uncertain Uncertain Vesicles NA NA 9500000 "Cluster 22: Eosinophils - Transcription" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 55: Lymphoma - Immune response" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 3 Vesicles "HPA008210: , HPA042273: " "unprognostic (2.98e-1)" "unprognostic (2.95e-2)" "unprognostic (1.42e-1)" "unprognostic (5.84e-2)" "unprognostic (3.33e-2)" "unprognostic (2.68e-2)" "unprognostic (4.06e-2)" "unprognostic (1.28e-1)" "unprognostic (2.81e-2)" "unprognostic (3.00e-2)" "unprognostic (1.56e-3)" "unprognostic (1.69e-1)" "unprognostic (3.61e-2)" "unprognostic (2.03e-3)" "unprognostic (1.11e-2)" "potential prognostic unfavorable (3.67e-4)" "unprognostic (2.80e-3)" "unprognostic (2.24e-2)" "unprognostic (1.46e-1)" "unprognostic (7.59e-2)" "unprognostic (3.62e-3)" "unprognostic (4.70e-3)" "unprognostic (3.00e-1)" "unprognostic (1.06e-2)" "unprognostic (2.48e-1)" "unprognostic (6.24e-2)" "unprognostic (1.81e-2)" "unprognostic (5.82e-2)" "unprognostic (5.34e-2)" SEMG1 "CT103, SEMG" ENSG00000124233 "Semenogelin 1" P04279 20 45207033-45209768 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 163 "seminal vesicle: 28650.3" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 1.8;Prostatic club cells: 1.8;Prostatic glandular cells: 2.9;Prostatic hillock cells: 3.1" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 18 "Prostate Adenocarcinoma (TCGA): 36.5" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 239 "eosinophil: 26.9" "Lineage enriched" "Detected in single" 269 "granulocytes: 26.9" "Cancer enhanced" "Detected in single" "colorectal cancer: 1.5" "HPA042476, HPA064892" Enhanced "Secreted in male reproductive system" "No annotated function" NA NA 2900000 "Cluster 19: Eosinophils - Unknown function" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 14 "HPA042476: , HPA064892: " "unprognostic (4.50e-1)" "unprognostic (1.51e-1)" "unprognostic (2.07e-1)" "potential prognostic unfavorable (7.78e-4)" "unprognostic (4.01e-1)" SEMG2 SGII ENSG00000124157 "Semenogelin 2" Q02383 20 45221373-45224458 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 163 "seminal vesicle: 9810.7" "Cell type enhanced" "Detected in some" "Early spermatids: 1.4;Late spermatids: 5.2;Papillary tip epithelial cells: 1.1;Prostatic club cells: 1.4;Renal collecting duct principal cells: 2.1" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 28 "Prostate Adenocarcinoma (TCGA): 16.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pituitary gland - Gonadotropes, Testis - Early spermatids, Testis - Late spermatids" "HPA042767, HPA042835" Enhanced "Secreted in male reproductive system" "No annotated function" NA NA 1900000 "Cluster 38: Non-specific - Basic cellular processes" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 13 "HPA042767: , HPA042835: " "unprognostic (1.23e-1)" SENP1 ENSG00000079387 "SUMO specific peptidase 1" Q9P0U3 12 48042897-48106079 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 30.5;testis: 57.7" "Cell type enhanced" "Detected in all" "Early primary spermatocytes: 119.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011765, HPA046491" Supported "Nucleoplasm,Focal adhesion sites" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 57: Testis - Spermatogenesis" "Cluster 16: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 21 Nucleoplasm "Focal adhesion sites" "HPA011765: , HPA046491: " "unprognostic (2.08e-1)" "unprognostic (6.98e-2)" "unprognostic (6.35e-2)" "unprognostic (3.71e-1)" "unprognostic (2.08e-1)" "unprognostic (8.62e-2)" "unprognostic (2.99e-1)" "unprognostic (1.82e-2)" "unprognostic (9.51e-2)" "unprognostic (6.74e-3)" "unprognostic (1.11e-2)" "unprognostic (7.61e-2)" "unprognostic (1.12e-1)" "potential prognostic unfavorable (2.89e-5)" "unprognostic (1.04e-2)" "unprognostic (3.02e-3)" "unprognostic (3.26e-2)" "unprognostic (3.41e-2)" "unprognostic (1.84e-1)" "unprognostic (9.26e-2)" "unprognostic (4.68e-2)" "unprognostic (1.62e-2)" "unprognostic (9.01e-3)" "unprognostic (3.17e-1)" "unprognostic (5.60e-2)" "unprognostic (5.78e-2)" "potential prognostic unfavorable (6.85e-4)" "unprognostic (1.19e-1)" "unprognostic (3.10e-1)" "unprognostic (1.86e-2)" "unprognostic (1.86e-1)" SENP2 "AXAM2, DKFZp762A2316, KIAA1331, SMT3IP2" ENSG00000163904 "SUMO specific peptidase 2" Q9HC62 3 185582496-185633551 "Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport, Ubl conjugation pathway, Wnt signaling pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 274.9;Late primary spermatocytes: 226.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029247, HPA029248" Approved Supported Cytosol NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 33: Neurons - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 41 Cytosol "HPA029247: , HPA029248: " "unprognostic (2.26e-1)" "unprognostic (9.30e-2)" "unprognostic (2.64e-1)" "unprognostic (1.71e-2)" "unprognostic (3.24e-2)" "unprognostic (2.97e-1)" "unprognostic (6.55e-2)" "unprognostic (3.86e-1)" "unprognostic (7.50e-2)" "unprognostic (5.61e-3)" "unprognostic (8.90e-2)" "unprognostic (3.18e-2)" "unprognostic (2.31e-2)" "unprognostic (6.53e-3)" "unprognostic (1.90e-2)" "unprognostic (1.28e-2)" "unprognostic (8.36e-2)" "unprognostic (1.11e-2)" "unprognostic (6.48e-3)" "unprognostic (1.24e-1)" "potential prognostic unfavorable (3.41e-4)" "unprognostic (1.51e-2)" "potential prognostic unfavorable (6.92e-4)" "potential prognostic unfavorable (5.62e-4)" "unprognostic (4.29e-2)" "unprognostic (1.71e-1)" "unprognostic (7.29e-2)" "unprognostic (1.21e-1)" "unprognostic (2.32e-1)" "unprognostic (4.36e-2)" "unprognostic (2.07e-1)" SENP3 "DKFZP586K0919, DKFZp762A152, SMT3IP1, SSP3, Ulp1" ENSG00000161956 "SUMO specific peptidase 3" Q9H4L4 17 7561919-7571969 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Astrocytes: 27.1;Bergmann glia: 20.5;Brain excitatory neurons: 12.8;Brain inhibitory neurons: 12.8;Choroid plexus epithelial cells: 19.4;Ependymal cells: 10.2;Microglia: 15.7;Oligodendrocyte progenitor cells: 14.1;Oligodendrocytes: 18.4;Other brain neurons: 10.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060290 Supported Supported Nucleoplasm,Nucleoli Yes No "Cluster 65: Brain - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 42: Non-specific - Unknown function" "Cluster 22: Non-specific - Basic cellular functions" 108 Nucleoli Nucleoplasm "HPA060290: " "unprognostic (2.34e-2)" "unprognostic (1.18e-1)" "unprognostic (2.25e-2)" "unprognostic (1.18e-1)" "unprognostic (1.69e-1)" "unprognostic (6.15e-2)" "unprognostic (2.31e-1)" "potential prognostic favorable (1.02e-4)" "unprognostic (2.21e-1)" "unprognostic (3.01e-2)" "potential prognostic favorable (4.06e-4)" "unprognostic (3.24e-2)" "unprognostic (9.04e-2)" "unprognostic (1.19e-3)" "unprognostic (4.48e-2)" "potential prognostic unfavorable (4.97e-4)" "unprognostic (3.44e-1)" "unprognostic (1.50e-1)" "unprognostic (2.54e-1)" "unprognostic (9.38e-2)" "unprognostic (9.79e-2)" "potential prognostic favorable (5.75e-4)" "unprognostic (1.73e-2)" "unprognostic (1.35e-2)" "unprognostic (6.12e-2)" "unprognostic (1.76e-1)" "unprognostic (1.86e-2)" "unprognostic (2.23e-1)" "unprognostic (3.03e-1)" "unprognostic (1.30e-2)" "unprognostic (1.61e-2)" SENP5 MGC27076 ENSG00000119231 "SUMO specific peptidase 5" Q96HI0 3 196867856-196934714 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 32: Basophils - Transcription" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 34: Non-specific - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 23 "unprognostic (1.31e-1)" "unprognostic (7.27e-3)" "unprognostic (1.82e-1)" "unprognostic (2.67e-1)" "unprognostic (5.29e-2)" "unprognostic (2.61e-1)" "unprognostic (2.31e-1)" "potential prognostic favorable (5.29e-4)" "unprognostic (1.87e-1)" "potential prognostic unfavorable (2.05e-5)" "unprognostic (1.87e-1)" "unprognostic (1.04e-1)" "unprognostic (6.08e-2)" "unprognostic (3.58e-3)" "unprognostic (2.31e-2)" "unprognostic (3.03e-2)" "unprognostic (2.18e-2)" "unprognostic (1.61e-1)" "unprognostic (6.32e-2)" "unprognostic (5.83e-2)" "unprognostic (3.33e-1)" "unprognostic (1.08e-1)" "unprognostic (6.60e-3)" "potential prognostic unfavorable (6.41e-4)" "unprognostic (3.60e-2)" "unprognostic (4.84e-3)" "unprognostic (9.68e-3)" "unprognostic (3.59e-1)" "unprognostic (4.13e-2)" "unprognostic (8.28e-3)" "unprognostic (6.06e-3)" SENP6 "KIAA0797, SUSP1" ENSG00000112701 "SUMO specific peptidase 6" Q9GZR1 6 75601509-75718281 "Enzymes, Essential proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024376 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 61: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" 10 Nucleoplasm Cytosol "HPA024376: " "unprognostic (1.53e-1)" "unprognostic (2.57e-2)" "unprognostic (1.03e-1)" "unprognostic (3.58e-3)" "unprognostic (1.40e-1)" "unprognostic (1.75e-1)" "unprognostic (8.00e-2)" "unprognostic (5.55e-2)" "unprognostic (8.46e-2)" "unprognostic (3.84e-3)" "potential prognostic favorable (9.78e-4)" "unprognostic (1.30e-2)" "unprognostic (6.48e-2)" "unprognostic (3.02e-2)" "unprognostic (2.43e-1)" "unprognostic (1.22e-1)" "unprognostic (2.22e-1)" "unprognostic (1.14e-1)" "unprognostic (8.49e-2)" "unprognostic (3.13e-1)" "unprognostic (1.03e-1)" "unprognostic (2.22e-1)" "unprognostic (7.19e-3)" "unprognostic (2.08e-1)" "unprognostic (5.04e-3)" "unprognostic (2.15e-2)" "unprognostic (1.55e-1)" "unprognostic (1.43e-1)" "unprognostic (5.87e-1)" "unprognostic (1.66e-2)" "potential prognostic unfavorable (7.75e-4)" SENP7 ENSG00000138468 "SUMO specific peptidase 7" Q9BQF6 3 101324205-101513241 "Enzymes, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 42.0" "Lineage enriched" "Detected in all" 4 "granulocytes: 42.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027259, HPA071998" Approved Supported "Nucleoplasm,Nuclear bodies,Centrosome,Cytosol" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 56: Non-specific - Sensory perception" "Cluster 7: Non-specific - Transcription" 7 Nucleoplasm "Nuclear bodies, Centrosome, Cytosol" "HPA027259: , HPA071998: " "unprognostic (8.32e-3)" "unprognostic (3.82e-1)" "unprognostic (1.15e-1)" "unprognostic (1.16e-1)" "unprognostic (1.85e-2)" "unprognostic (8.42e-2)" "unprognostic (2.98e-2)" "unprognostic (8.83e-3)" "potential prognostic favorable (3.68e-4)" "unprognostic (5.43e-3)" "unprognostic (1.43e-1)" "unprognostic (2.46e-3)" "unprognostic (4.23e-2)" "unprognostic (1.47e-2)" "unprognostic (7.74e-3)" "unprognostic (4.28e-3)" "unprognostic (1.84e-1)" "unprognostic (1.87e-1)" "unprognostic (6.02e-2)" "unprognostic (6.13e-2)" "unprognostic (7.22e-2)" "unprognostic (8.89e-2)" "unprognostic (6.40e-3)" "unprognostic (2.40e-1)" "unprognostic (1.72e-2)" "unprognostic (3.39e-2)" "unprognostic (9.97e-3)" "unprognostic (8.34e-2)" "unprognostic (4.35e-1)" "unprognostic (1.10e-1)" "unprognostic (3.59e-2)" SENP8 "DEN1, HsT17512, NEDP1, PRSC2" ENSG00000166192 "SUMO peptidase family member, NEDD8 specific" Q96LD8 15 72114258-72143692 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 14.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 210.3;Early spermatids: 122.9;Epicardial cells: 106.9;Late spermatids: 450.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036273 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 72: Kidney - Transmembrane transport" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 65: Non-specific - Cell growth & division" 7 "Nucleoplasm, Vesicles" "HPA036273: " "unprognostic (2.49e-2)" "unprognostic (9.34e-3)" "unprognostic (1.92e-1)" "unprognostic (4.11e-2)" "unprognostic (5.56e-3)" "unprognostic (1.52e-1)" "unprognostic (2.84e-1)" "unprognostic (5.20e-2)" "unprognostic (5.18e-2)" "unprognostic (1.64e-1)" "validated prognostic favorable (2.47e-10)" "validated prognostic favorable (2.47e-4)" "potential prognostic favorable (9.40e-4)" "unprognostic (1.56e-1)" "unprognostic (2.01e-2)" "unprognostic (1.48e-1)" "unprognostic (2.12e-2)" "unprognostic (9.55e-2)" "unprognostic (1.14e-1)" "unprognostic (6.09e-2)" "unprognostic (1.34e-1)" "unprognostic (9.69e-2)" "unprognostic (3.60e-2)" "unprognostic (1.47e-2)" "unprognostic (1.41e-1)" "unprognostic (2.22e-1)" "unprognostic (2.73e-1)" "unprognostic (3.32e-1)" "unprognostic (6.44e-3)" "unprognostic (4.26e-2)" SEPHS1 "SPS, SPS1" ENSG00000086475 "Selenophosphate synthetase 1" P49903 10 13317428-13348298 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037645, HPA062118" Enhanced Uncertain Nucleoplasm NA NA 13000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 76: Non-specific - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 19 Nucleoplasm "HPA037645: , HPA062118: " "unprognostic (1.48e-1)" "unprognostic (8.45e-3)" "unprognostic (2.44e-1)" "unprognostic (2.35e-2)" "unprognostic (3.84e-1)" "unprognostic (7.75e-2)" "unprognostic (8.32e-2)" "potential prognostic favorable (1.58e-5)" "unprognostic (1.10e-1)" "unprognostic (3.03e-1)" "potential prognostic favorable (1.05e-6)" "unprognostic (9.25e-2)" "unprognostic (1.28e-1)" "validated prognostic unfavorable (1.78e-4)" "validated prognostic unfavorable (9.40e-8)" "unprognostic (4.23e-2)" "unprognostic (4.72e-2)" "unprognostic (1.30e-1)" "unprognostic (7.58e-3)" "unprognostic (1.24e-1)" "unprognostic (4.07e-1)" "unprognostic (1.15e-2)" "unprognostic (1.44e-1)" "unprognostic (5.20e-2)" "unprognostic (9.64e-2)" "unprognostic (2.56e-1)" "unprognostic (1.14e-1)" "unprognostic (1.50e-1)" "unprognostic (6.77e-2)" "unprognostic (1.87e-1)" "unprognostic (9.29e-2)" SEPHS2 "SPS2, SPS2b" ENSG00000179918 "Selenophosphate synthetase 2" Q99611 16 30443631-30445874 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 377.1" "Cell type enhanced" "Detected in many" "Colonocytes: 213.0;Enterocytes: 373.2;Hepatocytes: 414.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Colon - Macrophages, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" HPA047931 Approved Approved Nucleoplasm No No 17000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 18: Liver cancer - Metabolism" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 5 Nucleoplasm "HPA047931: " "unprognostic (2.90e-1)" "unprognostic (8.36e-3)" "unprognostic (4.98e-2)" "unprognostic (2.51e-1)" "unprognostic (1.38e-1)" "unprognostic (2.76e-1)" "potential prognostic unfavorable (2.81e-4)" "unprognostic (9.07e-2)" "unprognostic (1.42e-1)" "unprognostic (1.48e-1)" "potential prognostic favorable (1.69e-9)" "unprognostic (2.55e-3)" "unprognostic (1.99e-1)" "unprognostic (4.14e-2)" "unprognostic (4.05e-3)" "unprognostic (2.03e-1)" "unprognostic (1.58e-1)" "unprognostic (4.82e-3)" "unprognostic (7.59e-2)" "unprognostic (2.89e-1)" "unprognostic (2.05e-1)" "unprognostic (2.12e-2)" "unprognostic (2.77e-1)" "unprognostic (2.57e-2)" "unprognostic (5.02e-2)" "unprognostic (4.81e-2)" "unprognostic (8.53e-2)" "unprognostic (8.05e-2)" "unprognostic (1.07e-1)" "unprognostic (3.11e-2)" "unprognostic (1.68e-1)" SEPSECS "SecS, SLA, SLA-p35, SLA/LP" ENSG00000109618 "Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase" Q9HD40 4 25120014-25160550 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Protein biosynthesis" "RNA-binding, Transferase, tRNA-binding" "Disease variant, Epilepsy, Intellectual disability, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 24.4" "Cell type enhanced" "Detected in many" "Hepatocytes: 74.0;Tuft cells: 69.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070409 Approved Vesicles NA NA "Cluster 16: Liver & Kidney - Metabolism" "Cluster 53: Neurons - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 7: Non-specific - Transcription" 2 Vesicles "HPA070409: " "unprognostic (3.50e-3)" "unprognostic (6.15e-2)" "unprognostic (3.40e-2)" "unprognostic (1.11e-1)" "unprognostic (6.40e-2)" "unprognostic (2.81e-1)" "unprognostic (1.49e-1)" "unprognostic (1.71e-2)" "unprognostic (8.35e-3)" "unprognostic (4.31e-1)" "validated prognostic favorable (2.06e-9)" "validated prognostic favorable (3.39e-4)" "unprognostic (2.09e-3)" "unprognostic (3.07e-3)" "unprognostic (1.67e-3)" "unprognostic (7.68e-2)" "unprognostic (1.37e-1)" "unprognostic (7.65e-2)" "unprognostic (2.88e-1)" "unprognostic (2.15e-1)" "unprognostic (2.81e-1)" "unprognostic (2.63e-1)" "unprognostic (2.92e-1)" "unprognostic (1.49e-1)" "unprognostic (9.65e-3)" "unprognostic (5.47e-2)" "unprognostic (2.29e-1)" "unprognostic (2.31e-1)" "unprognostic (3.06e-1)" "unprognostic (6.34e-2)" "unprognostic (1.24e-1)" SEPTIN1 "DIFF6, PNUTL3, SEPT1" ENSG00000180096 "Septin 1" Q8WYJ6 16 30378135-30395991 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 23.5;lymphoid tissue: 48.5" "Cell type enhanced" "Detected in many" "Megakaryocytes: 74.2;NK-cells: 71.9;pDCs: 69.5;Platelets: 112.3;T-cells: 96.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 36 "Leukemia: 42.1;lymphoma: 64.2;Myeloma: 30.6" "Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Heart muscle - T-cells, Liver - T-cells, Lung - T-cells, Pancreas - T-cells, Prostate - T-cells, Stomach - T-cells, Thyroid gland - T-cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA041566, HPA060339, HPA073635" Enhanced Approved "Actin filaments" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 16: Non-specific - Transcription" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" 32 "Actin filaments" "HPA041566: , HPA060339: , HPA073635: " "unprognostic (1.52e-1)" "potential prognostic favorable (7.79e-4)" "potential prognostic favorable (2.21e-4)" "unprognostic (2.10e-1)" "unprognostic (1.87e-1)" "potential prognostic favorable (1.80e-5)" "unprognostic (3.94e-2)" "unprognostic (2.02e-2)" "unprognostic (1.20e-1)" "unprognostic (4.91e-3)" "unprognostic (1.41e-3)" "potential prognostic favorable (4.18e-4)" "unprognostic (9.73e-2)" "unprognostic (1.72e-3)" "unprognostic (9.22e-3)" "unprognostic (3.49e-2)" "unprognostic (1.45e-1)" "unprognostic (5.92e-2)" "unprognostic (3.99e-2)" "unprognostic (4.41e-2)" "unprognostic (3.04e-2)" "unprognostic (2.81e-1)" "unprognostic (1.11e-2)" "unprognostic (1.50e-1)" "unprognostic (2.27e-1)" SEPTIN10 "FLJ11619, SEPT10" ENSG00000186522 "Septin 10" Q9P0V9 2 109542799-109614143 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 342.9;Esophageal apical cells: 479.9;Late spermatids: 668.4;Urothelial cells: 288.7" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 242.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 3.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056304 Enhanced Supported "Actin filaments,Microtubules,Annulus" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 57: Testis - Spermatogenesis" "Cluster 30: White matter - Myelination" "Cluster 72: Neuronal - Signal transduction" "Cluster 69: Urothelial cells - Basic cellular functions" 24 "Actin filaments" "Microtubules, Annulus" "HPA056304: " "unprognostic (2.21e-2)" "unprognostic (4.25e-2)" "unprognostic (2.22e-3)" "unprognostic (1.62e-1)" "unprognostic (1.55e-1)" "unprognostic (1.96e-1)" "unprognostic (1.66e-2)" "unprognostic (2.22e-1)" "unprognostic (1.24e-1)" "potential prognostic favorable (1.84e-7)" "unprognostic (3.09e-3)" "unprognostic (1.41e-1)" "unprognostic (4.07e-3)" "unprognostic (3.38e-3)" "unprognostic (1.50e-1)" "unprognostic (2.66e-1)" "unprognostic (2.03e-1)" "unprognostic (1.61e-1)" "unprognostic (1.50e-2)" "unprognostic (5.06e-3)" "potential prognostic unfavorable (7.58e-4)" "unprognostic (1.59e-1)" "unprognostic (5.34e-3)" "unprognostic (1.04e-1)" "unprognostic (9.02e-2)" "unprognostic (4.27e-2)" "unprognostic (2.96e-1)" "unprognostic (1.04e-1)" "unprognostic (3.17e-1)" SEPTIN11 "FLJ10849, SEPT11" ENSG00000138758 "Septin 11" Q9NVA2 4 76949751-77040384 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 462.5;Hepatic stellate cells: 387.3;Platelets: 517.8;Podocytes: 463.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Fibroblasts, Breast - Adipocytes (Breast), Prostate - Fibroblasts, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003459, HPA005665" Approved Approved "Primary cilium,Cytosol,Mid piece,Principal piece,Annulus" NA NA 2100000 "Cluster 41: Basophils - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 53: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 43 Cytosol "Primary cilium, Mid piece, Principal piece, Annulus" "HPA003459: , HPA005665: " "unprognostic (1.12e-2)" "unprognostic (1.43e-1)" "unprognostic (1.26e-1)" "unprognostic (1.48e-2)" "unprognostic (3.04e-2)" "unprognostic (2.02e-1)" "potential prognostic unfavorable (3.31e-4)" "unprognostic (2.52e-1)" "potential prognostic unfavorable (5.52e-4)" "potential prognostic favorable (1.24e-6)" "unprognostic (7.20e-3)" "unprognostic (6.77e-2)" "potential prognostic unfavorable (3.71e-5)" "unprognostic (1.12e-1)" "unprognostic (1.16e-3)" "unprognostic (1.53e-1)" "unprognostic (1.37e-1)" "unprognostic (1.40e-2)" "potential prognostic unfavorable (6.60e-4)" "unprognostic (6.86e-3)" "unprognostic (2.07e-1)" "unprognostic (1.11e-1)" "unprognostic (1.00e-1)" "unprognostic (1.91e-2)" "unprognostic (2.03e-3)" "unprognostic (1.18e-1)" "unprognostic (2.17e-1)" "unprognostic (3.89e-1)" "unprognostic (2.63e-1)" SEPTIN12 "FLJ25410, SEPT12" ENSG00000140623 "Septin 12" Q8IYM1 16 4777606-4788398 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Spermatogenesis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 37 "testis: 103.7" "Group enriched" "Detected in some" 16 "Early spermatids: 315.5;Late primary spermatocytes: 468.3;Late spermatids: 155.3" "Low cell type specificity" "Detected in some" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA041128 Supported Microtubules,Annulus NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 37: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 13 Microtubules Annulus "HPA041128: " SEPTIN14 "FLJ44060, SEPT14" ENSG00000154997 "Septin 14" Q6ZU15 7 55793540-55862755 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "testis: 21.2" "Cell type enriched" "Detected in some" 5 "Sertoli cells: 599.3" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Glioblastoma Multiforme (TCGA): 11.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Pituitary gland - Somatotropes, Testis - Sertoli cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA073255 Enhanced NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 9: Non-specific - Receptor signaling" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 6 "HPA073255: " "unprognostic (3.28e-1)" "unprognostic (3.71e-1)" "unprognostic (1.31e-3)" "unprognostic (2.08e-1)" "unprognostic (4.14e-2)" "unprognostic (4.21e-3)" "unprognostic (2.46e-1)" "unprognostic (1.22e-2)" "unprognostic (2.15e-1)" "unprognostic (9.55e-2)" SEPTIN2 "DIFF6, hNedd5, KIAA0158, NEDD5, Pnutl3, SEPT2" ENSG00000168385 "Septin 2" Q15019 2 241315100-241354027 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Mitosis, Spermatogenesis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017190, HPA018481, HPA063623" Supported Supported "Plasma membrane,Actin filaments,Microtubules,Cytokinetic bridge,Primary cilium,Principal piece,Annulus" Yes No 1500000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 55: Breast - Lactation" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 8: Non-specific - Secretory pathway" 51 "Actin filaments" "Plasma membrane, Microtubules, Cytokinetic bridge, Primary cilium, Principal piece, Annulus" "CAB017190: , HPA018481: , HPA063623: " "potential prognostic favorable (2.96e-6)" "unprognostic (1.35e-2)" "unprognostic (2.83e-2)" "unprognostic (1.11e-1)" "unprognostic (1.84e-1)" "unprognostic (9.28e-3)" "unprognostic (2.85e-3)" "unprognostic (1.45e-1)" "unprognostic (1.28e-2)" "potential prognostic favorable (8.54e-5)" "unprognostic (4.82e-2)" "potential prognostic unfavorable (5.10e-4)" "potential prognostic unfavorable (4.07e-4)" "unprognostic (2.90e-3)" "unprognostic (1.86e-1)" "unprognostic (5.65e-2)" "unprognostic (4.66e-1)" "unprognostic (2.50e-1)" "unprognostic (4.74e-2)" "unprognostic (4.39e-2)" "unprognostic (2.37e-2)" "unprognostic (2.97e-1)" "unprognostic (7.57e-2)" "unprognostic (5.84e-3)" "unprognostic (3.69e-2)" "unprognostic (6.45e-2)" "unprognostic (3.36e-2)" "unprognostic (2.13e-1)" "unprognostic (2.66e-1)" SEPTIN3 "SEP3, SEPT3" ENSG00000100167 "Septin 3" Q9UH03 22 41969443-41998221 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "brain: 253.5" "Cell type enhanced" "Detected in many" "Astrocytes: 21.9;Brain excitatory neurons: 55.5;Brain inhibitory neurons: 43.7;Choroid plexus epithelial cells: 18.8;Early spermatids: 30.3;Extravillous trophoblasts: 45.7;Late spermatids: 46.7;Melanocytes: 20.3;Oligodendrocyte progenitor cells: 22.2;Other brain neurons: 43.2;Pancreatic islet cells: 23.2;Retinal amacrine cells: 22.6;Retinal bipolar cells: 18.0;Retinal horizontal cells: 18.0" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Glioblastoma Multiforme (TCGA): 51.5;Skin Cutaneous Melanoma (TCGA): 23.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 48.8" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003548, CAB017633" Supported Supported Approved "Nucleoplasm,Plasma membrane,Actin filaments,Primary cilium" NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" 35 "Plasma membrane, Actin filaments" "Nucleoplasm, Primary cilium" "CAB017633: , HPA003548: " "unprognostic (4.23e-2)" "unprognostic (2.96e-1)" "unprognostic (1.47e-1)" "unprognostic (1.16e-1)" "unprognostic (2.51e-2)" "potential prognostic favorable (5.41e-4)" "unprognostic (9.51e-2)" "unprognostic (3.94e-3)" "unprognostic (1.96e-2)" "unprognostic (1.81e-3)" "unprognostic (4.48e-2)" "unprognostic (3.74e-2)" "unprognostic (3.79e-1)" "unprognostic (4.40e-2)" "unprognostic (5.09e-3)" "unprognostic (3.54e-1)" "unprognostic (1.32e-2)" "unprognostic (1.12e-1)" "unprognostic (7.04e-2)" "unprognostic (8.89e-2)" "unprognostic (1.54e-1)" "unprognostic (1.88e-2)" "unprognostic (1.73e-1)" "unprognostic (1.41e-2)" "unprognostic (1.26e-1)" "unprognostic (1.15e-2)" SEPTIN4 "ARTS, C17orf47, CE5B3, FLJ40121, H5, hCDCREL-2, hucep-7, MART, PNUTL2, SEPT4" ENSG00000108387 "Septin 4" O43236 17 58520250-58544368 "Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 1097.2;retina: 375.4" "Cell type enhanced" "Detected in many" "Bergmann glia: 936.7;Cone photoreceptor cells: 248.4;Late spermatids: 119.6;Oligodendrocytes: 275.1;Pericytes: 111.6;Retinal horizontal cells: 1097.9;Rod photoreceptor cells: 174.4" "Group enriched" "Detected in all" 5 "Bergmann glia: 991.8;oligodendrocyte: 296.5" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 65.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "skin cancer: 12.2" "Prostate - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "CAB006855, HPA021587, HPA022905, HPA028424" Enhanced Supported Annulus NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 109: Neurons - Neuronal signaling" 12 Annulus "CAB006855: , HPA021587: , HPA022905: , HPA028424: " "unprognostic (1.04e-1)" "unprognostic (2.45e-1)" "unprognostic (5.52e-2)" "unprognostic (2.70e-2)" "unprognostic (7.89e-3)" "unprognostic (4.32e-2)" "unprognostic (9.79e-3)" "unprognostic (3.58e-2)" "unprognostic (2.44e-1)" "unprognostic (1.82e-1)" "unprognostic (1.19e-3)" "potential prognostic unfavorable (1.32e-4)" "unprognostic (2.29e-3)" "unprognostic (1.34e-2)" "unprognostic (1.17e-1)" "unprognostic (1.09e-1)" "unprognostic (3.49e-2)" "unprognostic (7.28e-2)" "unprognostic (4.05e-2)" "unprognostic (7.87e-2)" "unprognostic (2.06e-3)" "unprognostic (4.55e-1)" "unprognostic (9.08e-2)" "unprognostic (8.71e-2)" "unprognostic (2.48e-1)" "potential prognostic unfavorable (9.76e-4)" "unprognostic (1.23e-1)" "unprognostic (1.16e-1)" "unprognostic (1.12e-2)" SEPTIN5 "H5, HCDCREL-1, PNUTL1, SEPT5" ENSG00000184702 "Septin 5" Q99719 22 19714503-19724224 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 531.3" "Cell type enhanced" "Detected in some" "Astrocytes: 9.1;Brain excitatory neurons: 42.0;Brain inhibitory neurons: 36.7;Choroid plexus epithelial cells: 44.7;Early spermatids: 8.4;Ependymal cells: 21.5;Late spermatids: 29.8;Oligodendrocyte progenitor cells: 10.2;Oligodendrocytes: 7.8;Other brain neurons: 25.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 32 "eosinophil: 15.5;neutrophil: 5.8" "Lineage enriched" "Detected in single" 47 "granulocytes: 15.5" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Lung - Smooth muscle cells, Pituitary gland - Corticotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016120, HPA029095, HPA063885" Enhanced Approved "Nucleoplasm,Actin filaments,Cytosol" NA NA 95000 "Cluster 21: Neutrophils - Unknown function" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" 46 "Nucleoplasm, Actin filaments, Cytosol" "CAB016120: , HPA029095: , HPA063885: " "unprognostic (3.78e-2)" "unprognostic (3.73e-1)" "unprognostic (1.16e-2)" "unprognostic (2.79e-3)" "potential prognostic unfavorable (7.23e-4)" "unprognostic (2.88e-1)" "unprognostic (4.20e-1)" "unprognostic (2.84e-1)" "unprognostic (4.34e-2)" "unprognostic (1.11e-1)" "unprognostic (1.57e-2)" "unprognostic (8.50e-3)" "unprognostic (3.62e-2)" "unprognostic (3.72e-2)" "unprognostic (1.74e-1)" "unprognostic (2.63e-1)" "unprognostic (1.77e-3)" "unprognostic (1.44e-1)" "unprognostic (1.00e-1)" "unprognostic (1.46e-2)" "unprognostic (4.41e-2)" "unprognostic (8.48e-2)" "unprognostic (7.54e-2)" "unprognostic (1.59e-1)" "unprognostic (1.00e-1)" "unprognostic (2.59e-2)" "unprognostic (2.96e-1)" "unprognostic (4.13e-2)" "unprognostic (1.19e-1)" SEPTIN6 "KIAA0128, MGC16619, MGC20339, SEP2, SEPT2, SEPT6" ENSG00000125354 "Septin 6" Q14141 X 119615724-119693370 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Host-virus interaction, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 215.5" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 280.0;B-cells: 262.5;cDC: 295.7;Hematopoietic stem cells: 396.4;Innate lymphoid cells: 312.9;Megakaryocyte-Erythroid progenitors: 245.8;NK-cells: 269.7;pDCs: 284.0;Platelets: 304.1;Sertoli cells: 476.5;T-cells: 343.1;Thymocytes: 521.7" "Cell type enhanced" "Detected in all" "leukocyte: 277.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Leukemia: 212.4;lymphoma: 198.6;Myeloma: 126.1;Neuroblastoma: 108.4" "Adrenal gland - Adrenal cortex cells, Breast - T-cells, Kidney - Fibroblasts, Skeletal muscle - Fibroblasts, Spleen - B-cells (Spleen), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003459, HPA005665" Supported Approved "Primary cilium,Cytosol,Mid piece,Principal piece" NA NA 2400000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 1: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" 44 Cytosol "Primary cilium, Mid piece, Principal piece" "HPA003459: , HPA005665: " "unprognostic (5.34e-3)" "unprognostic (1.03e-1)" "unprognostic (1.89e-1)" "unprognostic (1.28e-1)" "unprognostic (6.48e-2)" "unprognostic (1.56e-1)" "unprognostic (2.26e-1)" "unprognostic (1.98e-1)" "unprognostic (5.78e-2)" "unprognostic (2.26e-3)" "unprognostic (4.38e-2)" "unprognostic (1.39e-1)" "unprognostic (1.80e-1)" "unprognostic (4.26e-2)" "unprognostic (3.16e-2)" "unprognostic (5.89e-2)" "unprognostic (2.00e-1)" "unprognostic (8.85e-2)" "unprognostic (3.77e-1)" "unprognostic (1.68e-1)" "unprognostic (1.23e-2)" "unprognostic (3.21e-2)" "unprognostic (8.85e-2)" "unprognostic (2.76e-2)" "unprognostic (1.16e-1)" "unprognostic (1.81e-1)" "unprognostic (5.72e-2)" "unprognostic (1.36e-1)" "unprognostic (1.50e-1)" SEPTIN7 "CDC10, CDC3, SEPT7, SEPT7A" ENSG00000122545 "Septin 7" Q16181 7 35800932-35907110 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Mitosis, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 2033.4;Retinal horizontal cells: 1113.9" "Cell type enhanced" "Detected in all" "oligodendrocyte: 2662.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023309, HPA029524" Enhanced Supported "Actin filaments,Cytokinetic bridge,Midbody,Primary cilium" Yes No 4000000 "Cluster 24: Non-specific - Transcription" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 67: Non-specific - Unknown function" "Cluster 110: Mural cells - ECM organization" 46 "Actin filaments" "Cytokinetic bridge, Midbody, Primary cilium" "HPA023309: , HPA029524: " "unprognostic (2.42e-2)" "unprognostic (4.41e-2)" "unprognostic (1.09e-3)" "unprognostic (1.71e-2)" "unprognostic (3.59e-2)" "unprognostic (8.99e-2)" "unprognostic (1.27e-3)" "unprognostic (6.50e-2)" "unprognostic (5.58e-3)" "unprognostic (1.22e-3)" "unprognostic (4.70e-3)" "unprognostic (1.16e-1)" "unprognostic (1.56e-3)" "potential prognostic unfavorable (1.36e-4)" "unprognostic (1.49e-2)" "unprognostic (1.56e-1)" "unprognostic (1.82e-1)" "unprognostic (1.99e-1)" "potential prognostic unfavorable (3.25e-4)" "unprognostic (1.24e-1)" "unprognostic (6.65e-2)" "unprognostic (4.26e-1)" "unprognostic (2.85e-1)" "unprognostic (2.56e-1)" "unprognostic (2.30e-2)" "unprognostic (1.05e-3)" "unprognostic (4.24e-1)" "unprognostic (4.88e-2)" "unprognostic (1.11e-1)" SEPTIN8 "KIAA0202, SEP2, SEPT8" ENSG00000164402 "Septin 8" Q92599 5 132750819-132807241 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 11 "brain: 749.6" "Cell type enhanced" "Detected in many" "Bergmann glia: 118.6;Müller glia: 123.2;Oligodendrocyte progenitor cells: 107.7;Oligodendrocytes: 184.7;Retinal horizontal cells: 152.3;Retinal pigment epithelial cells: 89.5" "Cell type enhanced" "Detected in all" "oligodendrocyte: 259.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Fibroblasts, Skin - Keratinocyte (other), Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005665, HPA036534" Enhanced Approved "Actin filaments,Primary cilium,Cytosol,Mid piece,Principal piece,Annulus" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 11: Muller glia cells - Retinal homeostasis" 34 Cytosol "Actin filaments, Primary cilium, Mid piece, Principal piece, Annulus" "HPA005665: , HPA036534: " "potential prognostic favorable (3.19e-4)" "unprognostic (3.58e-2)" "unprognostic (2.38e-2)" "unprognostic (2.85e-1)" "unprognostic (1.37e-1)" "unprognostic (1.37e-1)" "unprognostic (3.46e-2)" "unprognostic (2.77e-1)" "unprognostic (6.89e-3)" "potential prognostic favorable (1.28e-5)" "unprognostic (5.19e-2)" "unprognostic (9.14e-2)" "unprognostic (1.85e-2)" "unprognostic (1.81e-2)" "unprognostic (7.81e-2)" "unprognostic (3.06e-2)" "unprognostic (3.65e-2)" "unprognostic (5.20e-3)" "unprognostic (5.65e-3)" "unprognostic (6.54e-2)" "unprognostic (1.29e-1)" "unprognostic (1.08e-1)" "unprognostic (9.42e-2)" "unprognostic (1.02e-1)" "unprognostic (3.58e-2)" "unprognostic (5.90e-2)" "unprognostic (2.04e-1)" "unprognostic (2.10e-2)" "unprognostic (3.26e-1)" SEPTIN9 "AF17q25, KIAA0991, MSF, MSF1, PNUTL4, SEPT9, SeptD1" ENSG00000184640 "Septin 9" Q9UHD8 17 77280569-77500596 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Urothelial cells: 517.5" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 219.7;leukocyte: 231.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042564, HPA050627" Approved Enhanced "Actin filaments,Microtubules,Cytokinetic bridge,Primary cilium" Yes No 160000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 44: Non-specific - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 69: Urothelial cells - Basic cellular functions" 46 "Actin filaments" "Microtubules, Cytokinetic bridge, Primary cilium" "HPA042564: , HPA050627: " "unprognostic (2.63e-2)" "unprognostic (2.15e-1)" "potential prognostic unfavorable (8.78e-4)" "unprognostic (4.39e-2)" "unprognostic (1.14e-1)" "unprognostic (3.04e-2)" "unprognostic (3.86e-2)" "unprognostic (6.43e-2)" "unprognostic (1.60e-2)" "potential prognostic favorable (2.14e-4)" "unprognostic (2.76e-2)" "unprognostic (1.92e-1)" "potential prognostic unfavorable (3.09e-6)" "unprognostic (1.82e-1)" "potential prognostic unfavorable (3.53e-4)" "unprognostic (1.08e-3)" "unprognostic (8.76e-2)" "unprognostic (8.48e-2)" "unprognostic (5.40e-2)" "unprognostic (5.08e-2)" "unprognostic (5.51e-3)" "unprognostic (1.89e-1)" "unprognostic (1.22e-1)" "unprognostic (1.13e-1)" "unprognostic (4.73e-2)" "unprognostic (3.39e-1)" "unprognostic (4.80e-2)" "unprognostic (7.35e-2)" "unprognostic (1.05e-1)" SERAC1 FLJ14917 ENSG00000122335 "Serine active site containing 1" Q96JX3 6 158109519-158168280 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 104.5;Late spermatids: 162.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025715, HPA025716" Enhanced NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 27: Non-specific - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 80: Oligodendrocytes - Myelination" 2 "HPA025715: , HPA025716: " "unprognostic (9.94e-3)" "potential prognostic unfavorable (4.14e-4)" "unprognostic (3.10e-3)" "unprognostic (2.23e-3)" "unprognostic (2.34e-2)" "unprognostic (7.05e-2)" "unprognostic (5.11e-1)" "unprognostic (3.12e-1)" "unprognostic (1.14e-1)" "unprognostic (1.61e-2)" "potential prognostic favorable (3.15e-6)" "unprognostic (2.49e-2)" "unprognostic (4.23e-1)" "unprognostic (6.84e-3)" "unprognostic (2.51e-2)" "unprognostic (5.67e-2)" "unprognostic (2.05e-1)" "unprognostic (1.21e-1)" "unprognostic (3.72e-2)" "unprognostic (8.55e-3)" "unprognostic (3.73e-2)" "unprognostic (1.12e-1)" "unprognostic (6.33e-2)" "unprognostic (2.07e-1)" "unprognostic (2.12e-1)" "unprognostic (6.56e-2)" "unprognostic (3.41e-2)" "unprognostic (1.20e-1)" "unprognostic (1.38e-1)" "unprognostic (4.99e-2)" "unprognostic (2.78e-1)" SERBP1 "CGI-55, CHD3IP, DKFZP564M2423, HABP4L, PAI-RBP1, PAIRBP1" ENSG00000142864 "SERPINE1 mRNA binding protein 1" Q8NC51 1 67407810-67430415 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Translation regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020559, CAB026297" Supported Enhanced Cytosol NA NA 380000 "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 208 Cytosol "CAB026297: , HPA020559: " "unprognostic (1.07e-3)" "unprognostic (4.04e-1)" "unprognostic (2.05e-1)" "unprognostic (1.28e-1)" "unprognostic (7.96e-3)" "unprognostic (3.00e-1)" "unprognostic (6.01e-3)" "unprognostic (2.64e-1)" "unprognostic (2.39e-1)" "unprognostic (1.99e-2)" "potential prognostic favorable (3.64e-7)" "unprognostic (3.60e-2)" "unprognostic (2.34e-2)" "validated prognostic unfavorable (3.83e-6)" "validated prognostic unfavorable (1.80e-5)" "validated prognostic unfavorable (4.89e-5)" "validated prognostic unfavorable (8.61e-4)" "unprognostic (8.62e-2)" "unprognostic (1.03e-1)" "unprognostic (1.43e-1)" "unprognostic (1.97e-2)" "unprognostic (4.28e-3)" "unprognostic (1.98e-2)" "unprognostic (6.74e-2)" "unprognostic (9.52e-2)" "unprognostic (3.67e-1)" "unprognostic (7.94e-2)" "unprognostic (7.47e-2)" "unprognostic (1.04e-1)" "unprognostic (1.53e-2)" "unprognostic (1.75e-1)" SERF1A "4F5, FAM2A, H4F5, SERF1, SMAM1" ENSG00000172058 "Small EDRK-rich factor 1A" O75920 5 70900669-70918530 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 133.8" "Cell type enhanced" "Detected in some" "Astrocytes: 1.7;Bergmann glia: 2.2;Brain excitatory neurons: 2.5;Brain inhibitory neurons: 2.1;Choroid plexus epithelial cells: 1.0;Ependymal cells: 1.3;Microglia: 1.6;Oligodendrocyte progenitor cells: 2.0;Oligodendrocytes: 1.4;Other brain neurons: 2.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075271 Uncertain "Nuclear bodies" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 67: Testis - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 22: Non-specific - Basic cellular functions" 11 "Nuclear bodies" "HPA075271: " "unprognostic (4.83e-3)" "unprognostic (1.04e-1)" "unprognostic (2.98e-1)" "unprognostic (9.55e-3)" "unprognostic (1.87e-1)" "unprognostic (2.54e-2)" "unprognostic (4.58e-1)" "unprognostic (3.04e-1)" "unprognostic (3.38e-1)" "unprognostic (1.75e-2)" "unprognostic (7.10e-3)" "unprognostic (1.50e-1)" "potential prognostic unfavorable (7.48e-4)" "unprognostic (3.05e-2)" "unprognostic (1.85e-1)" "unprognostic (1.05e-1)" "unprognostic (3.04e-1)" "unprognostic (5.00e-2)" "unprognostic (1.74e-2)" "unprognostic (9.61e-2)" "unprognostic (3.10e-3)" "unprognostic (2.22e-1)" "unprognostic (4.02e-1)" "unprognostic (1.08e-1)" "unprognostic (4.21e-2)" "unprognostic (3.66e-1)" "unprognostic (1.67e-1)" "unprognostic (5.74e-2)" "unprognostic (2.16e-2)" SERF1B "FAM2B, H4F5C" ENSG00000205572 "Small EDRK-rich factor 1B" O75920 5 70025247-70043113 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in single" "Podocytes: 1.0" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA075271 Approved "Nuclear bodies" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 105: Non-specific - Mixed function" 11 "Nuclear bodies" "HPA075271: " "unprognostic (2.13e-2)" "unprognostic (3.55e-2)" "unprognostic (1.89e-1)" "unprognostic (1.88e-1)" "unprognostic (2.60e-1)" "unprognostic (3.14e-2)" "unprognostic (1.64e-1)" "unprognostic (1.45e-2)" "unprognostic (7.42e-3)" "unprognostic (1.62e-1)" "unprognostic (2.83e-1)" "unprognostic (2.50e-2)" "unprognostic (2.47e-2)" "unprognostic (1.68e-3)" "unprognostic (3.25e-2)" "unprognostic (2.03e-1)" "unprognostic (8.04e-2)" "unprognostic (3.66e-1)" "unprognostic (1.55e-1)" SERF2 "4F5REL, FAM2C, H4F5rel, HsT17089" ENSG00000140264 "Small EDRK-rich factor 2" P84101 15 43777087-43804427 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 6819.6;Esophageal suprabasal cells: 5192.2;Extravillous trophoblasts: 4408.3;Parietal cells: 5365.6;Platelets: 4269.6" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 510.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA056613 Approved Nucleoplasm,Nucleoli NA Yes "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 8: Immune cells - Immune response" "Cluster 58: Non-specific - Nuclear processes" "Cluster 97: Non-specific - Cellular respiration" 1 Nucleoplasm Nucleoli "HPA056613: " "unprognostic (1.96e-1)" "unprognostic (6.04e-2)" "unprognostic (4.25e-2)" "unprognostic (1.54e-1)" "unprognostic (1.84e-2)" "unprognostic (2.38e-1)" "unprognostic (1.80e-1)" "unprognostic (2.35e-1)" "unprognostic (9.83e-2)" "unprognostic (3.63e-2)" "potential prognostic unfavorable (3.07e-5)" "unprognostic (3.71e-3)" "unprognostic (1.92e-1)" "unprognostic (2.18e-3)" "unprognostic (4.05e-3)" "unprognostic (1.77e-1)" "unprognostic (6.54e-2)" "unprognostic (1.86e-1)" "unprognostic (1.70e-1)" "unprognostic (3.31e-1)" "unprognostic (6.79e-2)" "unprognostic (1.19e-1)" "unprognostic (2.70e-1)" "unprognostic (6.65e-2)" "unprognostic (1.95e-2)" "unprognostic (8.31e-2)" "unprognostic (1.33e-1)" "unprognostic (1.39e-2)" "unprognostic (2.38e-2)" "unprognostic (9.98e-2)" "unprognostic (1.48e-1)" SERGEF "DelGEF, Gnefr" ENSG00000129158 "Secretion regulating guanine nucleotide exchange factor" Q9UGK8 11 17788048-18013047 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gonadotrophs: 249.3;Late spermatids: 397.1;Thyrotrophs: 258.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037811, HPA037812, HPA074086" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 73: Brain - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 13 Nucleoplasm Cytosol "HPA037811: , HPA037812: , HPA074086: " "unprognostic (5.89e-2)" "unprognostic (2.94e-2)" "unprognostic (5.19e-3)" "unprognostic (1.54e-1)" "unprognostic (1.68e-1)" "unprognostic (1.26e-3)" "unprognostic (4.17e-3)" "unprognostic (3.16e-1)" "unprognostic (2.15e-2)" "potential prognostic unfavorable (3.87e-4)" "validated prognostic favorable (5.19e-4)" "validated prognostic favorable (4.70e-4)" "unprognostic (4.24e-1)" "unprognostic (1.16e-3)" "unprognostic (1.87e-1)" "unprognostic (3.03e-2)" "unprognostic (2.07e-1)" "unprognostic (8.86e-2)" "unprognostic (2.89e-1)" "unprognostic (5.89e-3)" "unprognostic (4.59e-1)" "unprognostic (2.75e-2)" "unprognostic (1.38e-1)" "unprognostic (8.96e-2)" "unprognostic (3.67e-1)" "unprognostic (1.24e-1)" "unprognostic (9.45e-2)" "unprognostic (1.41e-1)" "unprognostic (1.88e-1)" "unprognostic (1.90e-2)" "unprognostic (3.31e-2)" SERHL2 ENSG00000183569 "Serine hydrolase like 2" Q9H4I8 22 42553617-42574382 "Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "breast: 399.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 49.9;Epicardial cells: 79.6;Epididymal principal cells: 50.3;Oocytes: 78.3" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" 7 "Breast Invasive Carcinoma (TCGA): 75.6;Prostate Adenocarcinoma (TCGA): 37.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "memory B-cell: 3.7;naive B-cell: 9.0;plasmacytoid DC: 4.3" "Group enriched" "Detected in many" 9 "B-cells: 9.0;dendritic cells: 4.3" "Cancer enriched" "Detected in all" 4 "breast cancer: 30.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 55: Breast - Lactation" "Cluster 34: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "unprognostic (4.16e-2)" "unprognostic (2.23e-1)" "unprognostic (2.90e-1)" "unprognostic (6.78e-3)" "unprognostic (4.64e-2)" "potential prognostic unfavorable (3.00e-4)" "unprognostic (3.89e-1)" "unprognostic (2.55e-2)" "unprognostic (4.44e-2)" "unprognostic (2.07e-1)" "unprognostic (2.45e-2)" "unprognostic (5.05e-2)" "unprognostic (2.00e-1)" "unprognostic (1.34e-1)" "unprognostic (7.65e-3)" "unprognostic (3.57e-2)" "unprognostic (2.53e-1)" "unprognostic (1.75e-1)" "unprognostic (1.08e-2)" "unprognostic (1.52e-2)" "unprognostic (1.08e-1)" "unprognostic (2.93e-1)" "unprognostic (8.26e-3)" "unprognostic (1.74e-1)" "unprognostic (9.76e-2)" "unprognostic (1.75e-1)" "unprognostic (1.07e-1)" SERINC1 "KIAA1253, TDE1L, TDE2, TMS-2" ENSG00000111897 "Serine incorporator 1" Q9NRX5 6 122443351-122471807 "Plasma proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 603.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Colon - Colon enteroendocrine cells, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035738, HPA035739" Uncertain Approved Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 27: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 17: Non-specific - RNA processing" 5 Cytosol "HPA035738: , HPA035739: " "unprognostic (2.01e-1)" "potential prognostic unfavorable (6.18e-4)" "unprognostic (4.27e-2)" "unprognostic (5.29e-3)" "unprognostic (2.17e-1)" "unprognostic (1.16e-3)" "unprognostic (1.19e-1)" "unprognostic (7.47e-2)" "unprognostic (5.93e-2)" "unprognostic (4.79e-2)" "validated prognostic favorable (5.59e-8)" "validated prognostic favorable (1.26e-4)" "unprognostic (8.48e-2)" "unprognostic (4.54e-2)" "unprognostic (2.46e-1)" "unprognostic (1.18e-1)" "unprognostic (1.05e-1)" "unprognostic (9.26e-3)" "unprognostic (1.94e-1)" "unprognostic (5.37e-3)" "potential prognostic unfavorable (6.44e-4)" "unprognostic (2.36e-2)" "unprognostic (3.08e-1)" "unprognostic (2.66e-1)" "unprognostic (1.35e-1)" "unprognostic (2.19e-2)" "unprognostic (8.67e-2)" "unprognostic (1.10e-2)" "unprognostic (1.68e-1)" "unprognostic (4.32e-1)" "unprognostic (2.20e-1)" SERINC2 "FKSG84, PRO0899, TDE2, TDE2L" ENSG00000168528 "Serine incorporator 2" Q96SA4 1 31409565-31434680 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 241.0" "Cell type enhanced" "Detected in many" "Breast lactating cells: 887.9;Colonocytes: 494.0;Cytotrophoblasts: 594.1;Enterocytes: 408.2;Esophageal apical cells: 1119.0;Salivary duct cells: 317.9;Syncytiotrophoblasts: 496.4;Urothelial cells: 339.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "plasmacytoid DC: 10.4" "Lineage enriched" "Detected in many" 4 "dendritic cells: 10.4" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Colon - Colon enterocytes, Minor Salivary Gland - Minor salivary glandular cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA005974 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 24 "Plasma membrane" Nucleoplasm "HPA005974: " "unprognostic (2.06e-1)" "unprognostic (1.82e-1)" "unprognostic (1.33e-2)" "potential prognostic unfavorable (4.50e-4)" "unprognostic (1.34e-3)" "unprognostic (2.37e-1)" "unprognostic (4.08e-2)" "unprognostic (1.60e-1)" "unprognostic (1.86e-2)" "unprognostic (2.29e-1)" "unprognostic (8.05e-3)" "unprognostic (2.68e-1)" "potential prognostic favorable (2.76e-6)" "potential prognostic unfavorable (2.15e-4)" "unprognostic (1.41e-1)" "unprognostic (3.95e-2)" "unprognostic (3.65e-2)" "unprognostic (2.86e-2)" "potential prognostic unfavorable (1.17e-4)" "unprognostic (6.38e-3)" "unprognostic (1.29e-1)" "unprognostic (5.70e-3)" "unprognostic (5.47e-2)" "unprognostic (7.05e-3)" "unprognostic (4.82e-2)" "unprognostic (2.75e-2)" "unprognostic (1.18e-2)" "unprognostic (1.27e-1)" "unprognostic (1.43e-1)" "unprognostic (3.82e-2)" "unprognostic (2.07e-2)" SERINC3 "AIGP1, DIFF33, SBBI99, TDE, TDE1, TMS-1" ENSG00000132824 "Serine incorporator 3" Q13530 20 44496221-44522085 "Predicted membrane proteins, Transporters" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 970.1;Neutrophils: 766.7;Platelets: 373.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048116 Uncertain NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 61: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 4 "HPA048116: " "unprognostic (5.16e-2)" "unprognostic (3.22e-2)" "unprognostic (4.66e-1)" "potential prognostic unfavorable (1.80e-7)" "unprognostic (1.63e-2)" "unprognostic (2.16e-1)" "unprognostic (2.07e-1)" "unprognostic (4.98e-2)" "unprognostic (8.28e-3)" "unprognostic (3.25e-3)" "potential prognostic favorable (6.65e-6)" "unprognostic (7.31e-3)" "unprognostic (5.91e-2)" "unprognostic (2.43e-2)" "unprognostic (1.46e-2)" "unprognostic (8.00e-2)" "unprognostic (7.45e-3)" "unprognostic (4.34e-3)" "potential prognostic unfavorable (3.71e-4)" "unprognostic (3.56e-3)" "potential prognostic unfavorable (1.91e-5)" "unprognostic (2.43e-2)" "unprognostic (6.70e-2)" "unprognostic (2.45e-1)" "unprognostic (1.14e-2)" "unprognostic (5.61e-2)" "unprognostic (1.68e-1)" "unprognostic (3.40e-2)" "unprognostic (1.22e-1)" "unprognostic (3.89e-2)" "unprognostic (7.50e-2)" SERINC4 FLJ40363 ENSG00000184716 "Serine incorporator 4" A6NH21 15 43794162-43800220 "Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "retina: 14.2" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 19.8;Choroid plexus epithelial cells: 12.4;Cone photoreceptor cells: 4.1;Epicardial cells: 6.8;Retinal pigment epithelial cells: 4.3;Rod photoreceptor cells: 12.5" "Cell type enriched" "Detected in some" 7 "choroid plexus epithelial cell: 29.7" "Group enriched" "Detected in some" 18 "Prostate Adenocarcinoma (TCGA): 2.7;Uterine Corpus Endometrial Carcinoma (TCGA): 1.6" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 42: Retina - Visual perception" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 1: Neuronal - Visual perception" "Cluster 101: Choroid plexus epithelial cells - Ion transport" "unprognostic (8.86e-2)" "unprognostic (3.49e-3)" "potential prognostic favorable (9.38e-5)" "unprognostic (1.39e-1)" "unprognostic (3.93e-1)" SERINC5 "C5orf12, TPO1" ENSG00000164300 "Serine incorporator 5" Q86VE9 5 80111651-80256048 "Predicted membrane proteins, Transporters" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity, Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 940.8;Prostatic glandular cells: 937.0;Sertoli cells: 709.6;Urothelial cells: 1070.6" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 623.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037898, HPA037899" Supported Supported "Vesicles,Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 76: Non-specific - Metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 51: Secretory epithelial cells - Mixed function" 3 "Plasma membrane, Cytosol" "Vesicles, Centrosome" "HPA037898: , HPA037899: " "unprognostic (6.38e-2)" "unprognostic (1.76e-1)" "unprognostic (3.75e-1)" "unprognostic (6.52e-2)" "unprognostic (2.39e-1)" "unprognostic (1.36e-1)" "unprognostic (5.46e-2)" "potential prognostic favorable (7.03e-4)" "unprognostic (4.57e-2)" "unprognostic (4.12e-2)" "validated prognostic favorable (1.10e-4)" "validated prognostic favorable (4.77e-4)" "unprognostic (3.59e-3)" "unprognostic (6.15e-2)" "unprognostic (2.02e-1)" "unprognostic (5.32e-2)" "unprognostic (7.21e-2)" "unprognostic (7.28e-2)" "unprognostic (2.80e-2)" "unprognostic (1.40e-1)" "unprognostic (1.32e-2)" "unprognostic (5.44e-2)" "unprognostic (6.05e-2)" "unprognostic (1.04e-1)" "unprognostic (1.98e-1)" "unprognostic (2.27e-1)" "unprognostic (1.35e-1)" "unprognostic (2.04e-1)" "unprognostic (1.50e-1)" "unprognostic (1.10e-1)" "unprognostic (1.51e-2)" SERP1 "FLJ43424, RAMP4" ENSG00000120742 "Stress associated endoplasmic reticulum protein 1" Q9Y6X1 3 150541998-150603228 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Translocation, Transport, Unfolded protein response" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1646.1;Syncytiotrophoblasts: 1232.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Stomach - Chief cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038970 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 70: Non-specific - Protein processing" "Cluster 7: Non-specific - Ribosome" "Cluster 63: Non-specific - Protein processing" "Cluster 8: Non-specific - Secretory pathway" 40 "Endoplasmic reticulum" "HPA038970: " "unprognostic (4.94e-2)" "unprognostic (2.99e-1)" "unprognostic (4.17e-1)" "unprognostic (9.67e-2)" "unprognostic (2.59e-1)" "unprognostic (1.65e-1)" "unprognostic (3.17e-1)" "unprognostic (2.07e-1)" "unprognostic (4.39e-1)" "unprognostic (6.95e-3)" "potential prognostic favorable (7.01e-4)" "unprognostic (3.69e-2)" "unprognostic (2.06e-2)" "unprognostic (2.00e-2)" "unprognostic (1.12e-3)" "unprognostic (3.33e-2)" "unprognostic (9.19e-2)" "potential prognostic favorable (6.52e-4)" "unprognostic (7.69e-2)" "unprognostic (9.18e-3)" "unprognostic (2.61e-2)" "potential prognostic unfavorable (8.33e-5)" "unprognostic (1.62e-1)" "unprognostic (8.82e-2)" "unprognostic (5.59e-2)" "unprognostic (1.63e-2)" "unprognostic (5.37e-2)" "unprognostic (1.51e-1)" "unprognostic (2.45e-1)" "unprognostic (2.39e-2)" "unprognostic (9.10e-3)" SERP2 "bA269C23.1, C13orf21" ENSG00000151778 "Stress associated endoplasmic reticulum protein family member 2" Q8N6R1 13 44373665-44397714 "Predicted intracellular proteins, Predicted membrane proteins" "Unfolded protein response" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 93.8;testis: 25.3" "Cell type enhanced" "Detected in many" "Early spermatids: 800.2;Late primary spermatocytes: 191.0;Late spermatids: 314.9" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 5 "Glioblastoma Multiforme (TCGA): 11.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.6" "Lineage enhanced" "Detected in single" "granulocytes: 2.6" "Cancer enhanced" "Detected in some" "Neuroblastoma: 5.1" "Heart muscle - Cardiomyocytes, Spleen - Fibroblasts_1, Testis - Late spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038970 Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 42 "Endoplasmic reticulum" "HPA038970: " "unprognostic (1.81e-1)" "unprognostic (1.58e-3)" "unprognostic (1.62e-1)" "unprognostic (3.10e-1)" "unprognostic (6.17e-2)" "unprognostic (1.10e-2)" "unprognostic (4.87e-3)" "unprognostic (4.27e-2)" "unprognostic (4.51e-3)" "unprognostic (1.76e-1)" "unprognostic (2.79e-2)" "potential prognostic favorable (2.46e-5)" "unprognostic (2.20e-1)" "unprognostic (1.66e-1)" "unprognostic (9.34e-2)" "unprognostic (5.58e-2)" "unprognostic (4.40e-2)" "unprognostic (9.37e-2)" SERPINA1 "A1A, A1AT, AAT, alpha-1-antitrypsin, alpha1AT, PI, PI1" ENSG00000197249 "Serpin family A member 1" P01009 14 94376747-94390693 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase, Blood coagulation, Hemostasis" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 29 "liver: 31416.7" "Cell type enhanced" "Detected in many" "Cholangiocytes: 2130.3;Enterocytes: 2752.3;Epididymal efferent duct absorptive cells: 2184.0;Hepatocytes: 9263.3" "Group enriched" "Detected in some" 8 "central nervous system macrophage: 14.8;leukocyte: 17.5" "Cancer enriched" "Detected in all" 10 "Liver Hepatocellular Carcinoma (TCGA): 15316.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 2484.3;intermediate monocyte: 3414.0;neutrophil: 2835.2;non-classical monocyte: 4540.7" "Group enriched" "Detected in all" 5 "granulocytes: 2835.2;monocytes: 4540.7" "Cancer enhanced" "Detected in many" "Gastric cancer: 303.1;liver cancer: 783.6;lymphoma: 293.1" "Adipose visceral - Neutrophils, Liver - Hepatocytes, Skeletal muscle - Neutrophils, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Spleen - Neutrophils_2" "Not detected" "Not detected" "HPA000927, HPA001292, CAB013211, CAB016648, CAB073396" Enhanced Enhanced Vesicles "Secreted to blood" "Blood coagulation" NA NA 1920000000000 230000000000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 53: Liver - Plasma proteins" "Cluster 12: Non-specific - Vasculature" "Cluster 18: Liver cancer - Metabolism" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 12 Vesicles "CAB013211: , CAB016648: , CAB073396: , HPA000927: , HPA001292: " "unprognostic (6.17e-2)" "potential prognostic favorable (7.55e-5)" "unprognostic (2.25e-1)" "unprognostic (8.51e-2)" "unprognostic (1.10e-2)" "unprognostic (2.00e-1)" "unprognostic (2.97e-2)" "unprognostic (1.56e-1)" "unprognostic (1.37e-2)" "unprognostic (3.87e-2)" "unprognostic (1.46e-3)" "unprognostic (2.45e-2)" "unprognostic (9.10e-3)" "unprognostic (2.02e-2)" "unprognostic (2.43e-2)" "unprognostic (3.09e-1)" "unprognostic (2.14e-1)" "unprognostic (2.43e-3)" "unprognostic (4.07e-2)" "unprognostic (2.00e-1)" "unprognostic (3.15e-1)" "unprognostic (4.03e-2)" "potential prognostic unfavorable (1.93e-4)" "unprognostic (3.00e-1)" "unprognostic (2.66e-1)" "unprognostic (1.98e-3)" "unprognostic (2.76e-2)" "unprognostic (1.98e-1)" "unprognostic (9.27e-3)" "unprognostic (2.76e-2)" "unprognostic (6.89e-2)" SERPINA10 "PZI, ZPI" ENSG00000140093 "Serpin family A member 10" Q9UK55 14 94280460-94293268 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 112 "liver: 320.0" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "hippocampal dentate gyrus: 1.1" "Cancer enriched" "Detected in some" 40 "Liver Hepatocellular Carcinoma (TCGA): 88.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Pancreas - Alpha cells, Stomach - Gastric enteroendocrine cells" "Not detected" "Not detected" HPA048739 Approved Nucleoplasm,Cytosol "Secreted to blood" "Blood coagulation" NA NA 3960000000 2400000000 "Cluster 53: Liver - Plasma proteins" "Cluster 9: Non-specific - Receptor signaling" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 98: Neurons - Neurotransmission & signaling" 8 Nucleoplasm Cytosol "HPA048739: " "unprognostic (1.14e-1)" "unprognostic (3.30e-1)" "unprognostic (1.12e-3)" "potential prognostic favorable (1.38e-5)" "unprognostic (3.75e-2)" "unprognostic (8.93e-3)" "potential prognostic favorable (8.86e-4)" "unprognostic (1.51e-3)" "unprognostic (3.34e-1)" "potential prognostic unfavorable (5.73e-4)" SERPINA11 ENSG00000186910 "Serpin family A member 11" Q86U17 14 94442464-94452800 "Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 92 "liver: 458.6" "Cell type enriched" "Detected in some" 21 "Hepatocytes: 272.2" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "Liver Hepatocellular Carcinoma (TCGA): 120.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "liver cancer: 4.9;lymphoma: 2.3" "Breast - Breast glandular cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Skin - Outer root sheath cells" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" "Enzyme inhibitor" NA NA 60000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 18: Liver cancer - Metabolism" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" "unprognostic (4.35e-2)" "unprognostic (7.59e-2)" "unprognostic (8.04e-3)" "potential prognostic favorable (1.45e-4)" "unprognostic (2.35e-1)" "unprognostic (2.08e-1)" SERPINA12 OL-64 ENSG00000165953 "Serpin family A member 12" Q8IW75 14 94487274-94517844 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "skin 1: 413.1" "Cell type enriched" "Detected in some" 11 "Suprabasal keratinocytes: 17.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Liver Hepatocellular Carcinoma (TCGA): 3.8;Skin Cutaneous Melanoma (TCGA): 4.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" "Enzyme inhibitor" NA NA 380000 "Cluster 37: Skin - Keratinization" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 26: Keratinocytes - Keratinization" 25 "unprognostic (1.60e-1)" "unprognostic (9.05e-3)" "unprognostic (2.52e-2)" "unprognostic (4.08e-2)" SERPINA2 "ARGS, ATR, PIL, SERPINA2P" ENSG00000258597 "Serpin family A member 2 (gene/pseudogene)" 14 94364316-94366698 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 1011 "epididymis: 101.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.8;non-classical monocyte: 2.2" "Group enriched" "Detected in many" 6 "granulocytes: 1.0;monocytes: 2.2" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in all" 6 "cerebellum: 206.0" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 51: Myeloma - Immunoglobulins" SERPINA3 "AACT, ACT" ENSG00000196136 "Serpin family A member 3" P01011 14 94612384-94624055 "Cancer-related genes, Candidate cardiovascular disease genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "liver: 8462.6;pancreas: 4871.0" "Cell type enriched" "Detected in some" 7 "Astrocytes: 9.4" "Cell type enriched" "Detected in some" 4 "astrocyte: 21.9" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 1460.8;Liver Hepatocellular Carcinoma (TCGA): 2219.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 142.2;skin cancer: 409.0" "Heart muscle - Macrophages, Kidney - Macrophages, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Macrophages, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Thyroid gland - Macrophages" "Not detected" "Not detected" "Not detected" "Not detected" "HPA000893, HPA002560, CAB016647" Enhanced "Secreted to blood" "Acute phase" NA NA 697000000000 130000000000 "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 39: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 28: Astrocytes - Homeostasis & neuron support" 34 "CAB016647: , HPA000893: , HPA002560: " "unprognostic (2.09e-3)" "unprognostic (2.38e-3)" "unprognostic (5.87e-2)" "potential prognostic unfavorable (3.46e-5)" "unprognostic (1.49e-1)" "unprognostic (1.38e-2)" "unprognostic (1.92e-2)" "unprognostic (1.61e-1)" "unprognostic (6.31e-2)" "unprognostic (1.31e-1)" "validated prognostic unfavorable (2.70e-10)" "validated prognostic unfavorable (9.92e-4)" "potential prognostic unfavorable (3.26e-5)" "unprognostic (2.89e-2)" "unprognostic (1.26e-2)" "unprognostic (5.50e-2)" "unprognostic (3.07e-1)" "unprognostic (8.18e-3)" "unprognostic (8.12e-3)" "unprognostic (7.54e-2)" "unprognostic (3.33e-1)" "unprognostic (3.00e-3)" "unprognostic (2.03e-3)" "unprognostic (2.06e-1)" "unprognostic (6.19e-3)" "unprognostic (1.50e-1)" "unprognostic (2.42e-1)" "unprognostic (1.64e-1)" "unprognostic (9.97e-2)" "potential prognostic unfavorable (2.90e-4)" "unprognostic (3.53e-2)" SERPINA4 "KAL, KLST, KST, PI4" ENSG00000100665 "Serpin family A member 4" P29622 14 94561442-94569913 "Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "liver: 514.2" "Cell type enhanced" "Detected in some" "Cholangiocytes: 11.8;Epididymal principal cells: 1.1;Gastric chief cells: 2.2;Hepatocytes: 9.4;Mucous neck cells: 2.4;Pancreatic acinar cells: 1.3;Pancreatic duct cells: 2.2;Parietal cells: 7.1" "Not detected" "Not detected" "Group enriched" "Detected in many" 8 "Liver Hepatocellular Carcinoma (TCGA): 166.5;Pancreatic Adenocarcinoma (TCGA): 42.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Bile duct cancer: 2.3;colorectal cancer: 1.5;Gastric cancer: 2.1;liver cancer: 5.6" "Liver - Hepatocytes, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Stomach - Parietal cells" "Not detected" "Not detected" "HPA003607, HPA068939" Approved Uncertain Vesicles "Secreted to blood" "Enzyme inhibitor" NA NA 14500000000 7700000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 18: Liver cancer - Metabolism" "Cluster 97: Non-specific - Cellular respiration" 3 Vesicles "HPA003607: , HPA068939: " "unprognostic (1.18e-1)" "unprognostic (3.14e-1)" "unprognostic (2.75e-1)" "unprognostic (1.75e-1)" "unprognostic (2.88e-2)" "potential prognostic unfavorable (7.74e-4)" "unprognostic (6.58e-2)" "unprognostic (4.48e-2)" "validated prognostic favorable (9.73e-4)" "validated prognostic favorable (3.41e-4)" "unprognostic (1.32e-2)" "unprognostic (2.50e-3)" "unprognostic (2.26e-2)" "unprognostic (6.20e-2)" "unprognostic (3.21e-1)" "unprognostic (1.64e-1)" "unprognostic (1.00e-1)" "unprognostic (1.84e-1)" "unprognostic (2.64e-1)" SERPINA5 "PAI3, PCI, PLANH3, PROCI" ENSG00000188488 "Serpin family A member 5" P05154 14 94561442-94593118 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Fertilization, Lipid transport, Transport" "Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 460.9;liver: 734.5;testis: 404.5" "Cell type enhanced" "Detected in some" "Adrenal cortex cells: 11.9;Cholangiocytes: 16.4;Distal convoluted tubule cells: 11.5;Early spermatids: 51.7;Endometrial luminal cells: 31.9;Hepatocytes: 15.3;Late spermatids: 84.1;Pancreatic duct cells: 17.7;Parietal cells: 10.6;Sertoli cells: 9.6" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 265.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 27.3;liver cancer: 67.0" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Pancreas - Macrophages, Skin - Fibroblasts_2, Stomach - Parietal cells, Testis - Sertoli cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA078846 Enhanced "Secreted to blood" Transport NA NA 1700000000 "Cluster 76: Non-specific - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 5 "HPA078846: " "unprognostic (4.43e-2)" "unprognostic (9.13e-3)" "unprognostic (4.37e-2)" "unprognostic (4.34e-3)" "unprognostic (2.29e-1)" "validated prognostic unfavorable (5.54e-5)" "validated prognostic unfavorable (9.94e-4)" "unprognostic (1.06e-1)" "potential prognostic unfavorable (2.63e-4)" "unprognostic (1.98e-2)" "unprognostic (1.78e-3)" "unprognostic (8.46e-2)" "unprognostic (8.91e-3)" "unprognostic (5.99e-3)" "unprognostic (3.02e-1)" "potential prognostic unfavorable (6.58e-5)" "unprognostic (1.08e-1)" "unprognostic (2.17e-2)" "unprognostic (1.05e-1)" "unprognostic (2.72e-3)" "unprognostic (3.47e-2)" "unprognostic (1.28e-1)" "unprognostic (4.06e-1)" "unprognostic (2.19e-3)" "unprognostic (6.44e-2)" "unprognostic (4.28e-3)" SERPINA6 CBG ENSG00000170099 "Serpin family A member 6" P08185 14 94304248-94323389 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "liver: 725.8" "Cell type enhanced" "Detected in some" "Cholangiocytes: 47.4;Endometrial ciliated cells: 20.5;Epididymal efferent duct ciliated cells: 12.6;Fallopian tube ciliated cells: 18.6;Hepatocytes: 47.4;Loop of henle epithelial cells: 7.6;Pancreatic duct cells: 5.0;Proximal tubule cells: 10.1" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 10 "Liver Hepatocellular Carcinoma (TCGA): 372.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 10.6;liver cancer: 21.0" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA017864 Approved "Secreted to blood" Transport NA NA 60800000000 10000000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 18: Liver cancer - Metabolism" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 2 "HPA017864: " "unprognostic (5.96e-2)" "unprognostic (1.78e-1)" "unprognostic (5.96e-2)" "unprognostic (1.11e-1)" "potential prognostic favorable (6.60e-4)" "unprognostic (1.66e-1)" "unprognostic (3.43e-1)" "unprognostic (1.12e-2)" "unprognostic (2.22e-3)" "unprognostic (3.87e-1)" "unprognostic (2.69e-3)" "unprognostic (2.15e-1)" "unprognostic (6.59e-2)" "unprognostic (3.60e-2)" "unprognostic (1.85e-2)" "unprognostic (3.36e-1)" SERPINA7 TBG ENSG00000123561 "Serpin family A member 7" P05543 X 106032435-106038727 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 608 "liver: 263.9" "Cell type enriched" "Detected in some" 23 "Hepatocytes: 169.4" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 201 "Liver Hepatocellular Carcinoma (TCGA): 108.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 18 "liver cancer: 5.5" "Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA002803 Approved "Secreted to blood" Transport NA NA 39800000000 8600000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 18: Liver cancer - Metabolism" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" "HPA002803: " "unprognostic (3.26e-3)" "potential prognostic favorable (8.19e-4)" SERPINA9 "GCET1, SERPINA11b" ENSG00000170054 "Serpin family A member 9" Q86WD7 14 94462717-94479689 "Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "lymphoid tissue: 68.0" "Cell type enhanced" "Detected in single" "B-cells: 2.2" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Breast Invasive Carcinoma (TCGA): 1.3;Stomach Adenocarcinoma (TCGA): 4.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 43 "lymphoma: 40.6" "Region enriched" "Detected in many" 16 "basal ganglia: 71.9" "Secreted to blood" "Enzyme inhibitor" NA NA "Cluster 18: Lymphoid tissue - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" "unprognostic (6.00e-2)" "unprognostic (1.93e-1)" "unprognostic (3.34e-1)" SERPINB1 "EI, ELANH2, LEI, MNEI, PI2" ENSG00000021355 "Serpin family B member 1" P30740 6 2832332-2841959 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 440.9;esophagus: 497.6" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 10956.9;Esophageal suprabasal cells: 3640.8;Neutrophil progenitors: 1114.7;Neutrophils: 1391.7;Pancreatic acinar cells: 2078.8" "Group enriched" "Detected in all" 4 "central nervous system macrophage: 50.1;choroid plexus epithelial cell: 19.8;endothelial cell: 66.7;ependymal cell: 22.4;fibroblast: 32.4;leukocyte: 49.3;oligodendrocyte: 23.0;pericyte: 52.0;vascular associated smooth muscle cell: 28.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018871, HPA018882, HPA052642" Enhanced Supported "Cytoplasmic bodies" "Secreted to blood" "Enzyme inhibitor" NA NA 26000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 85: Squamous epithelial cells - Keratinization" 2 "Cytoplasmic bodies" "HPA018871: , HPA018882: , HPA052642: " "unprognostic (8.16e-2)" "unprognostic (1.34e-2)" "unprognostic (1.11e-1)" "unprognostic (5.15e-2)" "unprognostic (4.57e-2)" "unprognostic (8.67e-2)" "potential prognostic unfavorable (1.00e-3)" "unprognostic (1.92e-2)" "unprognostic (5.95e-2)" "unprognostic (7.81e-3)" "potential prognostic favorable (2.04e-4)" "unprognostic (4.27e-2)" "unprognostic (4.48e-2)" "unprognostic (1.61e-3)" "unprognostic (6.81e-3)" "unprognostic (1.33e-1)" "unprognostic (1.38e-2)" "unprognostic (1.74e-2)" "unprognostic (5.42e-3)" "unprognostic (4.70e-3)" "unprognostic (1.51e-1)" "potential prognostic unfavorable (3.95e-4)" "unprognostic (2.20e-1)" "unprognostic (5.20e-2)" "unprognostic (2.10e-2)" "unprognostic (5.45e-2)" "unprognostic (1.45e-1)" "unprognostic (3.03e-1)" "unprognostic (6.24e-2)" "unprognostic (2.21e-1)" "unprognostic (4.21e-2)" SERPINB10 PI10 ENSG00000242550 "Serpin family B member 10" P48595 18 63907958-63936111 "Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 79 "bone marrow: 63.1" "Cell type enriched" "Detected in some" 4 "Neutrophil progenitors: 132.0" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 1.0" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in some" "Leukemia: 11.5;Myeloma: 4.1" "Adipose visceral - Mesothelial cells, Lung - Neutrophils_1, Spleen - Neutrophils_1" "Not detected" "Not detected" "Not detected" "Not detected" HPA059582 Supported Supported Nucleoplasm,Cytosol NA NA 35000 "Cluster 15: Bone marrow - Innate immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 1 Nucleoplasm Cytosol "HPA059582: " "unprognostic (1.53e-1)" "unprognostic (1.09e-1)" SERPINB11 ENSG00000206072 "Serpin family B member 11" Q96P15 18 63647579-63726432 "Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 25.7;prostate: 30.5" "Cell type enhanced" "Detected in some" "Conjunctival goblet cells: 656.3;Esophageal apical cells: 205.5;Esophageal suprabasal cells: 55.8;Prostatic club cells: 150.9;Prostatic glandular cells: 72.4;Prostatic hillock cells: 62.4;Respiratory basal cells: 62.4;Respiratory deuterosomal cells: 64.3;Respiratory secretory cells: 214.1" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Prostate Adenocarcinoma (TCGA): 19.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "colorectal cancer: 1.2" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.5" NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 7: Liver cancer - Metabolism" "Cluster 38: Secretory epithelial cells - Exocrine secretion" "unprognostic (5.70e-3)" "unprognostic (1.97e-1)" "unprognostic (3.18e-3)" "unprognostic (2.09e-1)" "unprognostic (4.50e-1)" "unprognostic (2.72e-1)" "unprognostic (6.06e-2)" "unprognostic (2.76e-1)" SERPINB12 ENSG00000166634 "Serpin family B member 12" Q96P63 18 63542369-63569329 "Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "cervix: 24.1;skin 1: 55.7;vagina: 37.0" "Cell type enhanced" "Detected in some" "Esophageal apical cells: 14.7;Esophageal suprabasal cells: 2.0;Late primary spermatocytes: 1.6;Suprabasal keratinocytes: 5.2;Syncytiotrophoblasts: 3.3" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 11.2;Head and Neck Squamous Cell Carcinoma (TCGA): 3.5;Lung Squamous Cell Carcinoma (TCGA): 5.9;Skin Cutaneous Melanoma (TCGA): 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 14 "head and neck cancer: 6.8;lung cancer: 2.7;Rhabdoid: 9.0" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 27000000 "Cluster 58: Skin - Keratinization" "Cluster 48: Non-specific - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 26: Keratinocytes - Keratinization" 5 "unprognostic (1.67e-2)" "unprognostic (2.76e-3)" "unprognostic (9.03e-3)" "unprognostic (1.73e-2)" "unprognostic (1.48e-1)" SERPINB13 "HUR7, PI13" ENSG00000197641 "Serpin family B member 13" Q9UIV8 18 63586989-63604639 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "cervix: 88.0;esophagus: 170.7;vagina: 128.9" "Group enriched" "Detected in some" 4 "Esophageal apical cells: 2013.5;Esophageal suprabasal cells: 709.4;Suprabasal keratinocytes: 593.7" "Cell type enhanced" "Detected in some" "hippocampal CA1-3: 2.6;hippocampal CA4: 4.3" "Cancer enhanced" "Detected in some" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 85.9;Head and Neck Squamous Cell Carcinoma (TCGA): 50.7;Lung Squamous Cell Carcinoma (TCGA): 41.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Bladder cancer: 9.3;cervical cancer: 32.3;Esophageal cancer: 15.6;Gallbladder cancer: 31.4;head and neck cancer: 27.4" "Prostate - Urothelial cells, Skin - Hair cortex cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA052630, HPA057129" Enhanced Approved "Nuclear speckles,Cytosol" NA NA 110000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 2 "Nuclear speckles, Cytosol" "HPA052630: , HPA057129: " "unprognostic (5.11e-2)" "unprognostic (3.22e-2)" "unprognostic (1.35e-1)" "potential prognostic favorable (5.11e-5)" "unprognostic (1.26e-1)" "potential prognostic unfavorable (5.13e-4)" "unprognostic (1.51e-1)" "unprognostic (2.67e-1)" SERPINB2 "HsT1201, PAI-2, PAI2, PLANH2" ENSG00000197632 "Serpin family B member 2" P05120 18 63871692-63903888 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Plasminogen activation" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 224.8;lymphoid tissue: 76.1;skin 1: 84.1" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 94.8;Conjunctival goblet cells: 37.9;Epicardial cells: 293.4;Esophageal apical cells: 156.3;Esophageal suprabasal cells: 57.3;Monocyte progenitors: 51.3;monocytes: 219.3;Ocular epithelial cells: 207.3;Suprabasal keratinocytes: 75.0" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Bladder Urothelial Carcinoma (TCGA): 30.6;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 43.2;Head and Neck Squamous Cell Carcinoma (TCGA): 69.1;Lung Squamous Cell Carcinoma (TCGA): 29.6" "Region enhanced" "Detected in some" "cerebral cortex: 2.9;thalamus: 2.5" "Immune cell enhanced" "Detected in some" "basophil: 22.1;eosinophil: 10.0" "Lineage enriched" "Detected in many" 4 "granulocytes: 22.1" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 326.1" "Minor Salivary Gland - Minor salivary gland basal cells, Pancreas - Ductal cells, Skin - Keratinocyte (other)" "Region enriched" "Detected in single" 15 "cerebellum: 2.6" "Not detected" "Not detected" "HPA015480, HPA076596, HPA076608" Enhanced "Intracellular and membrane" "Enzyme inhibitor" NA NA 1400000 "Cluster 22: Eosinophils - Transcription" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 12: Non-specific - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 29 "HPA015480: , HPA076596: , HPA076608: " "unprognostic (1.12e-1)" "unprognostic (9.97e-2)" "unprognostic (9.77e-2)" "unprognostic (4.46e-2)" "unprognostic (1.65e-1)" "unprognostic (2.38e-1)" "unprognostic (6.08e-2)" "unprognostic (1.86e-2)" "unprognostic (1.81e-1)" "unprognostic (2.40e-1)" "unprognostic (8.98e-2)" "unprognostic (2.03e-1)" "unprognostic (5.11e-2)" "unprognostic (1.36e-1)" "unprognostic (4.80e-3)" "unprognostic (2.13e-1)" "unprognostic (1.91e-1)" "unprognostic (2.69e-1)" "unprognostic (2.70e-2)" SERPINB3 "HsT1196, SCC, SCCA1, T4-A" ENSG00000057149 "Serpin family B member 3" P29508 18 63655197-63661893 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "cervix: 584.0;esophagus: 760.5;vagina: 669.9" "Group enriched" "Detected in some" 6 "Conjunctival goblet cells: 2009.7;Esophageal apical cells: 5517.0;Esophageal suprabasal cells: 4824.8;Respiratory basal cells: 2209.8;Respiratory deuterosomal cells: 2507.6;Respiratory secretory cells: 6921.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 565.0;Head and Neck Squamous Cell Carcinoma (TCGA): 220.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "head and neck cancer: 24.1;pancreatic cancer: 15.2" "Lung - Respiratory ciliated cells, Prostate - Urothelial cells, Testis - Early spermatids, Testis - Late spermatids" "CAB018772, CAB036006, CAB036007, HPA048341, HPA049988, HPA055992, HPA073892" Enhanced Supported "Plasma membrane,Cytosol" NA NA 28000000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 85: Squamous epithelial cells - Keratinization" 39 Cytosol "Plasma membrane" "CAB018772: , CAB036006: , CAB036007: , HPA048341: , HPA049988: , HPA055992: , HPA073892: " "unprognostic (6.24e-2)" "unprognostic (8.31e-2)" "unprognostic (5.42e-3)" "unprognostic (3.10e-1)" "unprognostic (1.66e-1)" "unprognostic (2.92e-1)" "unprognostic (9.56e-2)" "unprognostic (4.58e-2)" "unprognostic (3.30e-1)" "unprognostic (1.75e-1)" "unprognostic (1.45e-1)" "potential prognostic unfavorable (4.25e-4)" "unprognostic (1.24e-2)" "unprognostic (1.53e-2)" "unprognostic (1.02e-1)" "unprognostic (2.30e-1)" "unprognostic (2.36e-1)" "unprognostic (6.38e-1)" "unprognostic (5.16e-2)" SERPINB4 "LEUPIN, PI11, SCCA-2, SCCA1, SCCA2" ENSG00000206073 "Serpin family B member 4" P48594 18 63637259-63644256 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "cervix: 149.2;esophagus: 92.0;vagina: 150.8" "Group enriched" "Detected in some" 4 "Esophageal apical cells: 1423.9;Esophageal suprabasal cells: 1304.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 226.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "head and neck cancer: 12.2;lymphoma: 42.8" "Testis - Early spermatids, Testis - Late spermatids" "HPA048341, HPA049988, HPA055992, HPA073892, CAB080099" Enhanced Supported "Plasma membrane,Cytosol" NA NA 14000000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 85: Squamous epithelial cells - Keratinization" 45 Cytosol "Plasma membrane" "CAB080099: , HPA048341: , HPA049988: , HPA055992: , HPA073892: " "unprognostic (1.67e-3)" "unprognostic (6.85e-3)" "unprognostic (1.32e-2)" "unprognostic (2.53e-1)" "unprognostic (3.70e-3)" "unprognostic (1.96e-1)" "unprognostic (7.78e-2)" "unprognostic (2.13e-2)" "potential prognostic unfavorable (2.97e-4)" "unprognostic (1.76e-3)" "unprognostic (3.46e-1)" "unprognostic (7.44e-2)" SERPINB5 "maspin, PI5" ENSG00000206075 "Serpin family B member 5" P36952 18 63476958-63505085 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 203.5;skin 1: 242.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 963.4;Esophageal apical cells: 562.3;Esophageal basal cells: 608.3;Esophageal suprabasal cells: 896.8;Ocular epithelial cells: 1129.7;Respiratory basal cells: 274.5;Suprabasal keratinocytes: 1153.2;Urothelial cells: 250.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 169.3;Head and Neck Squamous Cell Carcinoma (TCGA): 272.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 125.2" "Breast - Breast myoepithelial cells, Minor Salivary Gland - Minor salivary gland basal cells, Skin - Keratinocyte (other), Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB009570, HPA019025, HPA019132, HPA020136" Enhanced Supported Vesicles "Intracellular and membrane" "No annotated function" NA NA 310000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 13 Vesicles "CAB009570: , HPA019025: , HPA019132: , HPA020136: " "unprognostic (1.07e-1)" "unprognostic (1.64e-2)" "unprognostic (2.06e-1)" "unprognostic (2.42e-2)" "unprognostic (8.85e-2)" "unprognostic (3.91e-2)" "unprognostic (5.26e-2)" "unprognostic (2.79e-1)" "unprognostic (6.07e-1)" "potential prognostic unfavorable (8.66e-5)" "unprognostic (1.98e-1)" "unprognostic (5.44e-2)" "unprognostic (1.47e-1)" "unprognostic (1.11e-2)" "potential prognostic unfavorable (1.14e-5)" "unprognostic (1.34e-1)" "unprognostic (1.18e-1)" "unprognostic (2.77e-1)" "unprognostic (3.04e-2)" "unprognostic (8.04e-2)" "unprognostic (1.94e-1)" "unprognostic (1.73e-1)" "unprognostic (4.37e-2)" SERPINB6 "CAP, DFNB91, PI6, PTI" ENSG00000124570 "Serpin family B member 6" P35237 6 2948159-2972165 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 595.7;Esophageal apical cells: 981.9;Late primary spermatocytes: 595.8;Late spermatids: 1570.5;Pancreatic acinar cells: 691.4" "Cell type enhanced" "Detected in all" "endothelial cell: 428.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Vascular endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "HPA009668, HPA012736" Enhanced Approved Centrosome NA NA 3100000 "Cluster 29: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 6: Non-specific - Immune response" "Cluster 5: Rhabdoid - Unknown function" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 2 Centrosome "HPA009668: , HPA012736: " "unprognostic (4.14e-1)" "unprognostic (3.16e-2)" "unprognostic (2.20e-1)" "unprognostic (5.51e-3)" "unprognostic (7.16e-2)" "unprognostic (1.96e-2)" "unprognostic (2.16e-3)" "potential prognostic unfavorable (1.77e-5)" "unprognostic (1.03e-2)" "unprognostic (4.53e-2)" "validated prognostic favorable (3.78e-5)" "validated prognostic favorable (2.98e-4)" "unprognostic (4.26e-2)" "potential prognostic unfavorable (2.43e-4)" "unprognostic (3.24e-2)" "unprognostic (7.24e-2)" "unprognostic (1.13e-2)" "unprognostic (5.14e-3)" "potential prognostic unfavorable (3.13e-4)" "unprognostic (5.29e-3)" "unprognostic (1.19e-2)" "unprognostic (1.16e-1)" "unprognostic (1.19e-1)" "unprognostic (9.79e-2)" "unprognostic (3.55e-2)" "unprognostic (4.18e-3)" "unprognostic (4.57e-2)" "unprognostic (1.00e-1)" "unprognostic (3.26e-1)" "unprognostic (2.32e-1)" "unprognostic (2.53e-1)" SERPINB7 ENSG00000166396 "Serpin family B member 7" O75635 18 63752935-63805376 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "lymphoid tissue: 36.0;skin 1: 122.1" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 82.8;Esophageal apical cells: 16.4;Extravillous trophoblasts: 121.6;Foveolar cells: 16.9;Migrating cytotrophoblasts: 28.4;Respiratory secretory cells: 26.5;Suprabasal keratinocytes: 23.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 17.8;Head and Neck Squamous Cell Carcinoma (TCGA): 16.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Stomach - Gastric mucous cells" "Not detected" "Not detected" "Group enriched" "Detected in some" 25 "cerebral cortex: 17.0;hippocampal formation: 15.1" HPA024200 Enhanced Approved "Endoplasmic reticulum,Mitochondria" NA NA 160000 "Cluster 37: Skin - Keratinization" "Cluster 72: Neuronal - Signal transduction" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 23 "Endoplasmic reticulum" Mitochondria "HPA024200: " "unprognostic (7.38e-2)" "unprognostic (1.35e-2)" "unprognostic (2.49e-2)" "unprognostic (4.12e-3)" "unprognostic (1.54e-2)" "unprognostic (1.77e-1)" "unprognostic (1.76e-1)" "unprognostic (3.86e-3)" "unprognostic (2.02e-1)" "unprognostic (1.42e-1)" "unprognostic (2.28e-2)" "potential prognostic unfavorable (1.45e-5)" "unprognostic (1.49e-1)" "unprognostic (2.88e-2)" "unprognostic (2.52e-1)" "unprognostic (8.29e-2)" SERPINB8 "CAP2, PI8" ENSG00000166401 "Serpin family B member 8" P50452 18 63970029-64019779 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 55.1" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 168.2;Esophageal suprabasal cells: 81.2;Monocyte progenitors: 107.2;monocytes: 85.1;Neutrophils: 50.9;Ocular epithelial cells: 49.4;Suprabasal keratinocytes: 56.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB034300, HPA070605" Enhanced Approved "Golgi apparatus,Actin filaments,Cytosol" NA NA 600000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 58: Skin - Keratinization" "Cluster 49: Hindbrain - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 11 "Golgi apparatus, Actin filaments" Cytosol "CAB034300: , HPA070605: " "unprognostic (1.41e-2)" "unprognostic (3.72e-2)" "unprognostic (1.20e-1)" "unprognostic (2.76e-2)" "unprognostic (5.33e-2)" "unprognostic (1.26e-1)" "unprognostic (3.57e-2)" "unprognostic (7.90e-2)" "unprognostic (3.09e-2)" "unprognostic (8.85e-2)" "unprognostic (4.78e-2)" "unprognostic (7.30e-2)" "unprognostic (1.17e-1)" "unprognostic (5.42e-2)" "unprognostic (1.57e-1)" "unprognostic (2.61e-2)" "unprognostic (8.56e-2)" "unprognostic (4.18e-2)" "unprognostic (1.68e-1)" "unprognostic (1.27e-2)" "unprognostic (1.78e-1)" "unprognostic (2.13e-3)" "unprognostic (5.83e-2)" "unprognostic (2.60e-1)" "unprognostic (1.76e-2)" "unprognostic (1.78e-1)" "unprognostic (8.29e-2)" "unprognostic (7.58e-2)" "unprognostic (1.07e-2)" "unprognostic (4.43e-1)" "unprognostic (2.57e-1)" SERPINB9 "CAP3, PI9" ENSG00000170542 "Serpin family B member 9" P50453 6 2887270-2903309 "Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 38.5;placenta: 49.1" "Cell type enhanced" "Detected in many" "cDC: 925.9;Macrophages: 356.9;Microglia: 301.7;Migrating cytotrophoblasts: 281.1;monocytes: 690.8;Plasma cells: 291.6;Retinal ganglion cells: 359.2;Syncytiotrophoblasts: 464.7" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 350.5" "Cancer enriched" "Detected in all" 5 "Testicular Germ Cell Tumor (TCGA): 69.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 8 "lymphoma: 60.9;testis cancer: 209.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA030067 Uncertain Approved Nucleoplasm,Cytosol NA NA 1600000 "Cluster 33: Non-specific - ATP binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 45: Non-specific - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 3 Nucleoplasm Cytosol "HPA030067: " "unprognostic (2.81e-1)" "unprognostic (1.12e-2)" "unprognostic (7.59e-3)" "unprognostic (6.18e-2)" "unprognostic (5.79e-1)" "unprognostic (3.12e-1)" "unprognostic (3.54e-1)" "unprognostic (1.16e-1)" "unprognostic (8.61e-2)" "potential prognostic unfavorable (3.37e-4)" "unprognostic (2.57e-1)" "unprognostic (1.33e-1)" "unprognostic (3.04e-1)" "unprognostic (2.56e-3)" "unprognostic (5.49e-2)" "unprognostic (1.35e-1)" "unprognostic (3.19e-3)" "unprognostic (2.41e-2)" "unprognostic (1.31e-2)" "unprognostic (7.20e-2)" "unprognostic (3.67e-1)" "unprognostic (3.70e-2)" "unprognostic (1.82e-3)" "unprognostic (1.39e-1)" "unprognostic (5.68e-2)" "unprognostic (4.85e-2)" "unprognostic (4.24e-2)" "unprognostic (6.83e-2)" "unprognostic (1.38e-1)" "unprognostic (3.96e-1)" "unprognostic (3.15e-3)" SERPINC1 "AT3, ATIII, MGC22579" ENSG00000117601 "Serpin family C member 1" P01008 1 173903800-173917327 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 1345 "liver: 4726.5" "Cell type enriched" "Detected in some" 82 "Hepatocytes: 3199.3" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 629 "Liver Hepatocellular Carcinoma (TCGA): 2227.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Gastric cancer: 1.6;liver cancer: 5.7" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA001816, CAB016790, HPA024007" Supported "Secreted to blood" "Blood coagulation" NA NA 76000000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 18: Liver cancer - Metabolism" "Cluster 93: Hepatocytes - Bile production & excretion" "CAB016790: , HPA001816: , HPA024007: " "unprognostic (4.53e-2)" "unprognostic (4.40e-2)" "validated prognostic favorable (3.41e-5)" "validated prognostic favorable (4.37e-5)" "unprognostic (6.24e-2)" SERPIND1 "D22S673, HC-II, HC2, HCF2, HLS2" ENSG00000099937 "Serpin family D member 1" P05546 22 20774113-20787720 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Chemotaxis, Hemostasis" "Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 1171.6" "Cell type enriched" "Detected in many" 5 "Hepatocytes: 326.3" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 13.3" "Cancer enriched" "Detected in many" 44 "Liver Hepatocellular Carcinoma (TCGA): 487.1" "Region enriched" "Detected in all" 21 "choroid plexus: 191.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 15 "liver cancer: 30.6;ovarian cancer: 66.9" "Liver - Hepatocytes, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "CAB008639, HPA055767" Supported Approved Vesicles "Secreted to blood" "Blood coagulation" NA NA 24000000000 "Cluster 30: Non-specific - DNA binding" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 36: Choroid plexus - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 4 Vesicles "CAB008639: , HPA055767: " "unprognostic (1.60e-2)" "unprognostic (5.58e-3)" "potential prognostic unfavorable (8.85e-4)" "unprognostic (1.08e-2)" "unprognostic (1.40e-1)" "unprognostic (1.04e-2)" "unprognostic (1.09e-1)" "potential prognostic unfavorable (2.39e-4)" "unprognostic (2.85e-1)" "unprognostic (2.59e-2)" "unprognostic (8.58e-3)" "unprognostic (2.06e-1)" "unprognostic (1.45e-1)" "unprognostic (1.19e-1)" "unprognostic (5.35e-2)" SERPINE1 "PAI, PAI1, PLANH1" ENSG00000106366 "Serpin family E member 1" P05121 7 101127104-101139247 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 620.0;placenta: 392.6" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 801.5;Fibroblasts: 432.0;Hepatic stellate cells: 1065.0;Hepatocytes: 349.1;Leydig cells: 323.6;Migrating cytotrophoblasts: 468.3;Ovarian stromal cells: 1151.2;Syncytiotrophoblasts: 1606.5;Vascular endothelial cells: 374.4" "Group enriched" "Detected in many" 4 "central nervous system macrophage: 99.2;endothelial cell: 130.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 25 "NK-cell: 9.5" "Lineage enriched" "Detected in single" 25 "NK-cells: 9.5" "Cancer enhanced" "Detected in all" "Kidney cancer: 1620.4" "Colon - Neutrophils, Testis - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" CAB068501 Uncertain "Secreted to blood" "Enzyme inhibitor" NA No 142000000 16000000 "Cluster 14: Non-specific - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 12: Non-specific - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 94: Gonadal somatic cells - Mixed function" 16 "CAB068501: " "unprognostic (1.72e-2)" "unprognostic (2.62e-2)" "unprognostic (6.80e-2)" "unprognostic (4.90e-3)" "unprognostic (3.34e-2)" "unprognostic (1.35e-1)" "unprognostic (3.57e-2)" "potential prognostic unfavorable (1.69e-4)" "potential prognostic unfavorable (2.87e-5)" "unprognostic (3.77e-3)" "unprognostic (9.10e-3)" "unprognostic (1.35e-1)" "unprognostic (3.14e-3)" "unprognostic (1.90e-3)" "unprognostic (1.94e-1)" "potential prognostic unfavorable (4.74e-4)" "unprognostic (1.34e-3)" "validated prognostic unfavorable (1.13e-4)" "validated prognostic unfavorable (4.14e-5)" "unprognostic (5.39e-2)" "unprognostic (2.82e-1)" "potential prognostic unfavorable (4.02e-4)" "unprognostic (1.93e-2)" "unprognostic (2.44e-1)" "unprognostic (1.76e-1)" "unprognostic (1.08e-2)" "unprognostic (2.12e-1)" "potential prognostic unfavorable (7.06e-6)" "unprognostic (2.98e-1)" "unprognostic (1.03e-2)" "unprognostic (5.80e-3)" SERPINE2 "GDN, nexin, PI7, PN1, PNI" ENSG00000135919 "Serpin family E member 2" P07093 2 223975045-224039318 "Plasma proteins, Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein, Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "ovary: 276.5;placenta: 1024.8" "Cell type enhanced" "Detected in many" "Astrocytes: 313.1;Bergmann glia: 462.2;Epididymal efferent duct absorptive cells: 252.0;Extravillous trophoblasts: 941.1;Fibroblasts: 472.2;Granulosa cells: 675.6;Leydig cells: 344.9;Melanocytes: 361.7;Oligodendrocyte progenitor cells: 295.7;Ovarian stromal cells: 446.4" "Cell type enhanced" "Detected in many" "astrocyte: 364.2;Bergmann glia: 536.0;oligodendrocyte precursor cell: 322.2" "Cancer enriched" "Detected in all" 4 "Skin Cutaneous Melanoma (TCGA): 1674.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "naive CD4 T-cell: 13.0;naive CD8 T-cell: 6.9;NK-cell: 23.3" "Group enriched" "Detected in many" 15 "NK-cells: 23.3;T-cells: 13.0" "Cancer enriched" "Detected in all" 5 "skin cancer: 2214.3" "Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000277 Approved "Golgi apparatus" "Secreted in female reproductive system" "Developmental protein" NA NA 7900000 "Cluster 24: Non-specific - Transcription" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 2 "Golgi apparatus" "HPA000277: " "unprognostic (4.13e-2)" "unprognostic (1.77e-1)" "unprognostic (8.32e-2)" "unprognostic (6.11e-2)" "unprognostic (1.04e-2)" "unprognostic (4.36e-2)" "unprognostic (2.73e-3)" "unprognostic (2.88e-1)" "unprognostic (6.75e-2)" "potential prognostic unfavorable (1.75e-4)" "unprognostic (2.95e-2)" "potential prognostic unfavorable (6.53e-5)" "unprognostic (7.49e-2)" "unprognostic (8.93e-3)" "unprognostic (1.64e-1)" "unprognostic (2.62e-3)" "unprognostic (8.63e-2)" "unprognostic (1.11e-1)" "unprognostic (3.25e-1)" "unprognostic (1.54e-1)" "unprognostic (1.78e-1)" "unprognostic (2.26e-2)" "potential prognostic unfavorable (1.02e-4)" "unprognostic (3.55e-1)" "unprognostic (1.48e-1)" "potential prognostic favorable (4.77e-4)" "unprognostic (3.75e-1)" "unprognostic (5.01e-3)" "unprognostic (1.39e-1)" "unprognostic (6.64e-2)" "unprognostic (7.77e-2)" SERPINE3 ENSG00000253309 "Serpin family E member 3" A8MV23 13 51335773-51364735 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "pancreas: 1.2;retina: 1.7" "Cell type enhanced" "Detected in many" "Breast secretory cells: 44.7;Epicardial cells: 275.2;Epididymal basal cells: 119.7;pDCs: 102.8" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Adipose visceral - Mesothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA051904, HPA055804" Uncertain "Secreted in other tissues" "Enzyme inhibitor" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 15: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 20: Non-specific - Transcription regulation" "HPA051904: , HPA055804: " SERPINF1 "EPC-1, PEDF, PIG35" ENSG00000132386 "Serpin family F member 1" P36955 17 1762029-1777565 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Dwarfism, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "choroid plexus: 4585.5" "Group enriched" "Detected in many" 4 "Decidual stromal cells: 3858.4;Retinal pigment epithelial cells: 4429.2" "Cell type enriched" "Detected in all" 7 "choroid plexus epithelial cell: 368.9" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 638.2" "Region enriched" "Detected in all" 20 "choroid plexus: 3985.5" "Immune cell enriched" "Detected in many" 18 "plasmacytoid DC: 1458.3" "Lineage enriched" "Detected in all" 121 "dendritic cells: 1458.3" "Cancer enhanced" "Detected in many" "Rhabdoid: 156.0" "Adipose visceral - Macrophages, Adrenal gland - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatocytes, Lung - Fibroblasts_2, Spleen - Fibroblasts_2, Thyroid gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005825 Uncertain "Secreted to blood" "No annotated function" NA NA 9290000000 11000000000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 10 "HPA005825: " "unprognostic (3.03e-2)" "unprognostic (2.63e-1)" "unprognostic (2.34e-1)" "unprognostic (4.95e-2)" "unprognostic (7.34e-2)" "unprognostic (7.85e-2)" "unprognostic (4.63e-2)" "unprognostic (7.01e-2)" "unprognostic (6.23e-2)" "unprognostic (3.64e-3)" "potential prognostic unfavorable (1.10e-4)" "unprognostic (9.13e-2)" "unprognostic (5.20e-2)" "unprognostic (1.46e-2)" "potential prognostic favorable (5.17e-5)" "unprognostic (2.16e-2)" "unprognostic (4.31e-2)" "unprognostic (1.19e-1)" "unprognostic (4.56e-1)" "unprognostic (1.68e-2)" "unprognostic (1.63e-2)" "unprognostic (1.79e-1)" "unprognostic (8.66e-2)" "unprognostic (5.63e-2)" "unprognostic (3.43e-2)" "unprognostic (1.40e-2)" "unprognostic (5.62e-2)" "unprognostic (3.56e-3)" "unprognostic (1.05e-1)" "unprognostic (9.56e-3)" "unprognostic (1.59e-1)" SERPINF2 "A2AP, AAP, ALPHA-2-PI, alpha2AP, API, PLI" ENSG00000167711 "Serpin family F member 2" P08697 17 1742836-1755265 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Acute phase" "Protease inhibitor, Serine protease inhibitor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 16 "liver: 1497.5" "Cell type enriched" "Detected in some" 4 "Proximal tubule cells: 107.8" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 15.3" "Cancer enriched" "Detected in all" 4 "Liver Hepatocellular Carcinoma (TCGA): 478.7" "Region enriched" "Detected in all" 7 "choroid plexus: 21.0" "Immune cell enriched" "Detected in some" 4 "plasmacytoid DC: 44.8" "Lineage enriched" "Detected in many" 23 "dendritic cells: 44.8" "Group enriched" "Detected in many" 14 "Gastric cancer: 46.8;liver cancer: 36.6" "Heart muscle - Macrophages, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA001885, HPA005943, CAB024863" Approved Approved "Golgi apparatus" "Secreted to blood" "Acute phase" NA NA 11900 31000000000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 36: Choroid plexus - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 88: Proximal tubular cells - Transmembrane transport" 4 "Golgi apparatus" "CAB024863: , HPA001885: , HPA005943: " "potential prognostic unfavorable (6.90e-4)" "unprognostic (4.97e-2)" "unprognostic (1.64e-1)" "unprognostic (2.28e-2)" "unprognostic (3.39e-1)" "unprognostic (3.82e-1)" "unprognostic (6.81e-2)" "unprognostic (2.58e-1)" "unprognostic (2.98e-3)" "unprognostic (1.25e-1)" "unprognostic (7.79e-3)" "unprognostic (2.45e-3)" "unprognostic (7.51e-3)" "unprognostic (1.83e-3)" "unprognostic (2.08e-3)" "unprognostic (9.24e-2)" "unprognostic (2.91e-1)" "unprognostic (3.74e-2)" "unprognostic (1.42e-1)" "unprognostic (1.04e-1)" "unprognostic (1.90e-1)" "potential prognostic unfavorable (9.39e-6)" "unprognostic (1.05e-1)" "unprognostic (1.77e-1)" "unprognostic (3.38e-1)" "unprognostic (2.46e-1)" "unprognostic (3.48e-1)" "unprognostic (2.19e-1)" "unprognostic (6.79e-2)" "unprognostic (8.43e-3)" SERPING1 "C1-INH, C1IN, C1INH, C1NH, HAE1, HAE2" ENSG00000149131 "Serpin family G member 1" P05155 11 57597387-57619171 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis" "Protease inhibitor, Serine protease inhibitor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 2454.0" "Cell type enhanced" "Detected in many" "Cholangiocytes: 594.4;Decidual stromal cells: 2144.7;Fibroblasts: 889.5;Hepatocytes: 2775.5;Leydig cells: 712.3;Mesothelial cells: 692.1;Ovarian stromal cells: 466.2;Pancreatic duct cells: 639.3;Pericytes: 450.8" "Group enriched" "Detected in many" 4 "ependymal cell: 68.6;fibroblast: 154.2;pericyte: 114.2;vascular associated smooth muscle cell: 96.8" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 1194.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 65.5;plasmacytoid DC: 60.7" "Group enriched" "Detected in many" 231 "dendritic cells: 60.7;granulocytes: 65.5;monocytes: 25.7" "Cancer enhanced" "Detected in many" "liver cancer: 37.5;testis cancer: 38.7" "Adrenal gland - Fibroblasts, Heart muscle - Fibroblasts, Liver - Hepatocytes, Lung - Fibroblasts_1, Prostate - Fibroblasts, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 255.7" "CAB026161, HPA048738" Supported "Secreted to blood" "Blood coagulation" NA NA 48000000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 8: Immune cells - Immune response" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 9 "CAB026161: , HPA048738: " "unprognostic (1.05e-2)" "unprognostic (2.83e-2)" "unprognostic (4.30e-3)" "unprognostic (8.28e-3)" "unprognostic (7.33e-3)" "unprognostic (1.61e-2)" "unprognostic (4.37e-2)" "potential prognostic unfavorable (1.84e-4)" "unprognostic (2.17e-1)" "unprognostic (4.37e-1)" "unprognostic (7.82e-2)" "unprognostic (1.50e-1)" "unprognostic (1.02e-1)" "validated prognostic favorable (1.17e-4)" "validated prognostic favorable (1.07e-6)" "unprognostic (1.41e-1)" "unprognostic (1.08e-1)" "unprognostic (3.78e-2)" "unprognostic (6.06e-2)" "unprognostic (8.18e-2)" "unprognostic (6.26e-2)" "unprognostic (1.04e-2)" "unprognostic (1.25e-1)" "unprognostic (9.61e-2)" "unprognostic (4.55e-2)" "unprognostic (5.47e-2)" "unprognostic (3.03e-2)" "unprognostic (1.32e-2)" "unprognostic (1.80e-1)" "unprognostic (1.72e-1)" "unprognostic (3.16e-1)" SERPINH1 "CBP1, CBP2, HSP47, SERPINH2" ENSG00000149257 "Serpin family H member 1" P50454 11 75562056-75572783 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Stress response" Chaperone "Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 254.6;Decidual stromal cells: 560.8;Endometrial stromal cells: 208.6;Epididymal efferent duct absorptive cells: 307.1;Extravillous trophoblasts: 477.3;Fibroblasts: 193.9;Hepatic stellate cells: 445.4;Migrating cytotrophoblasts: 247.5;Ovarian stromal cells: 200.0;Pancreatic duct cells: 236.0;Smooth muscle cells: 208.7" "Cell type enhanced" "Detected in many" "endothelial cell: 100.0;fibroblast: 57.2;pericyte: 75.1;vascular associated smooth muscle cell: 62.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004441, HPA029198" Supported Supported "Endoplasmic reticulum" "Intracellular and membrane" Other NA Yes 780000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 12: Non-specific - Vasculature" "Cluster 5: Rhabdoid - Unknown function" "Cluster 108: Fibroblasts - ECM organization" 54 "Endoplasmic reticulum" "CAB004441: , HPA029198: " "unprognostic (1.51e-1)" "unprognostic (1.03e-1)" "unprognostic (1.09e-1)" "potential prognostic unfavorable (1.39e-5)" "unprognostic (1.31e-2)" "unprognostic (1.39e-1)" "unprognostic (2.54e-2)" "unprognostic (7.24e-3)" "unprognostic (1.86e-3)" "unprognostic (6.59e-2)" "unprognostic (1.64e-3)" "unprognostic (5.95e-3)" "potential prognostic unfavorable (1.04e-4)" "unprognostic (1.95e-3)" "unprognostic (4.08e-2)" "validated prognostic unfavorable (1.93e-4)" "validated prognostic unfavorable (9.64e-6)" "unprognostic (1.59e-2)" "unprognostic (6.40e-2)" "unprognostic (1.96e-1)" "unprognostic (1.09e-1)" "unprognostic (2.35e-2)" "unprognostic (7.49e-2)" "unprognostic (7.23e-3)" "unprognostic (2.16e-1)" "unprognostic (2.06e-1)" "unprognostic (1.09e-2)" "unprognostic (1.72e-2)" "unprognostic (2.83e-1)" "unprognostic (4.17e-2)" "unprognostic (1.87e-1)" SERPINI1 PI12 ENSG00000163536 "Serpin family I member 1" Q99574 3 167735243-167825569 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "brain: 303.7;retina: 78.2" "Cell type enhanced" "Detected in many" "Bergmann glia: 78.5;Brain excitatory neurons: 130.5;Brain inhibitory neurons: 134.8;Gonadotrophs: 87.7;Oligodendrocytes: 171.3;Other brain neurons: 112.8;Retinal bipolar cells: 179.2;Vascular smooth muscle cells: 84.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 67.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "breast cancer: 47.8;thyroid cancer: 73.8" "Heart muscle - Smooth muscle cells, Kidney - Proximal tubular cells, Minor Salivary Gland - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Chief cells, Testis - Spermatogonia, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001565, HPA056092" Enhanced Uncertain Cytosol "Secreted in brain" "Enzyme inhibitor" NA NA 210000 "Cluster 24: Non-specific - Transcription" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 53: Neurons - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 2 Cytosol "HPA001565: , HPA056092: " "unprognostic (6.61e-2)" "unprognostic (8.23e-2)" "unprognostic (2.17e-1)" "unprognostic (2.64e-2)" "unprognostic (1.71e-2)" "unprognostic (2.07e-1)" "unprognostic (7.42e-2)" "unprognostic (1.46e-1)" "unprognostic (1.32e-1)" "unprognostic (8.69e-2)" "validated prognostic favorable (8.55e-6)" "validated prognostic favorable (1.76e-4)" "unprognostic (1.68e-1)" "potential prognostic unfavorable (7.05e-4)" "unprognostic (4.68e-2)" "unprognostic (8.66e-2)" "unprognostic (9.57e-2)" "unprognostic (1.79e-2)" "unprognostic (2.77e-3)" "unprognostic (4.23e-2)" "unprognostic (9.50e-3)" "unprognostic (8.87e-2)" "potential prognostic unfavorable (9.86e-4)" "unprognostic (8.08e-2)" "unprognostic (1.36e-1)" "unprognostic (5.25e-2)" "unprognostic (1.46e-1)" "unprognostic (1.52e-2)" "unprognostic (2.02e-1)" "unprognostic (2.50e-1)" "unprognostic (4.63e-1)" SERPINI2 "MEPI, PI14, TSA2004" ENSG00000114204 "Serpin family I member 2" O75830 3 167441914-167478972 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 265 "pancreas: 1338.6" "Cell type enhanced" "Detected in many" "Astrocytes: 153.1;Bergmann glia: 337.4;Choroid plexus epithelial cells: 243.6;Endometrial ciliated cells: 132.3;Ependymal cells: 620.9;Epididymal efferent duct ciliated cells: 94.0;Fallopian tube ciliated cells: 133.2;Pancreatic acinar cells: 623.1;Pituicytes/FSCs: 105.9;Podocytes: 146.9;Respiratory ciliated cells: 460.7;Respiratory deuterosomal cells: 98.5;Respiratory ionocytes: 127.0" "Group enriched" "Detected in many" 23 "astrocyte: 287.9;Bergmann glia: 313.9;choroid plexus epithelial cell: 201.7;ependymal cell: 729.7" "Cancer enriched" "Detected in some" 6 "Pancreatic Adenocarcinoma (TCGA): 18.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Leukemia: 1.2" "Kidney - Podocytes, Lung - Respiratory ciliated cells" "Not detected" "Not detected" "Region enhanced" "Detected in many" "midbrain: 11.3" "Secreted to digestive system" "Enzyme inhibitor" NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 39: Astrocytes - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 34: Ciliated cells - Cilia assembly & function" 7 "unprognostic (6.09e-2)" "unprognostic (2.65e-2)" "unprognostic (1.75e-3)" "unprognostic (1.65e-1)" "unprognostic (1.58e-3)" "unprognostic (8.69e-2)" SERTAD1 "SEI1, TRIP-Br1" ENSG00000197019 "SERTA domain containing 1" Q9UHV2 19 40421589-40425992 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast lactating cells: 298.7;Breast secretory cells: 420.6;Endometrial secretory cells: 310.8;Epididymal basal cells: 447.7;Esophageal apical cells: 708.6" "Cell type enhanced" "Detected in many" "endothelial cell: 36.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063323 Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 44: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 20: Non-specific - Transcription regulation" 33 "Golgi apparatus" Nucleoplasm "HPA063323: " "unprognostic (1.02e-1)" "unprognostic (3.54e-2)" "unprognostic (1.12e-1)" "unprognostic (3.44e-2)" "unprognostic (3.79e-1)" "unprognostic (1.30e-1)" "unprognostic (1.66e-1)" "unprognostic (2.38e-2)" "unprognostic (9.92e-2)" "unprognostic (7.81e-2)" "unprognostic (2.82e-3)" "unprognostic (2.37e-2)" "unprognostic (3.87e-1)" "unprognostic (2.02e-1)" "potential prognostic favorable (3.03e-4)" "unprognostic (7.01e-2)" "unprognostic (6.96e-2)" "potential prognostic unfavorable (8.86e-4)" "unprognostic (3.73e-3)" "unprognostic (3.45e-2)" "unprognostic (3.80e-1)" "unprognostic (6.33e-2)" "unprognostic (1.11e-1)" "unprognostic (1.36e-1)" "unprognostic (5.05e-2)" "unprognostic (1.56e-1)" "unprognostic (9.97e-2)" "unprognostic (1.63e-1)" "unprognostic (1.52e-1)" "unprognostic (1.03e-1)" "unprognostic (3.37e-1)" SERTAD2 "KIAA0127, Sei-2, TRIP-Br2" ENSG00000179833 "SERTA domain containing 2" Q14140 2 64631621-64751005 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 80.9" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 288.7;Urothelial cells: 285.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019021, HPA020904" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 11: White matter - Signal transduction" "Cluster 5: Rhabdoid - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 24 Nucleoplasm Cytosol "HPA019021: , HPA020904: " "unprognostic (1.84e-1)" "unprognostic (3.64e-2)" "unprognostic (1.35e-2)" "unprognostic (1.83e-1)" "unprognostic (1.16e-1)" "unprognostic (3.00e-1)" "unprognostic (5.96e-2)" "unprognostic (4.25e-3)" "unprognostic (6.31e-2)" "unprognostic (2.91e-2)" "potential prognostic favorable (1.16e-6)" "unprognostic (2.45e-2)" "unprognostic (1.19e-1)" "unprognostic (5.57e-3)" "unprognostic (5.92e-2)" "unprognostic (1.62e-2)" "unprognostic (9.52e-3)" "unprognostic (2.40e-1)" "unprognostic (9.31e-3)" "unprognostic (1.64e-2)" "unprognostic (5.41e-2)" "unprognostic (5.27e-3)" "potential prognostic unfavorable (1.16e-4)" "unprognostic (1.83e-1)" "unprognostic (1.36e-2)" "unprognostic (1.53e-2)" "unprognostic (5.27e-1)" "unprognostic (5.33e-3)" "unprognostic (3.28e-1)" "unprognostic (2.15e-1)" "potential prognostic unfavorable (3.37e-4)" SERTAD3 RBT1 ENSG00000167565 "SERTA domain containing 3" Q9UJW9 19 40440844-40444335 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 115.7;Breast secretory cells: 113.9;Esophageal apical cells: 131.3;Extravillous trophoblasts: 140.2;Migrating cytotrophoblasts: 122.5;Syncytiotrophoblasts: 223.3" "Cell type enhanced" "Detected in many" "vascular associated smooth muscle cell: 14.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068262 Approved Nucleoli NA Yes "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 6: Non-specific - Immune response" "Cluster 4: Non-specific - Transcription" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 42 Nucleoli "HPA068262: " "unprognostic (1.64e-2)" "unprognostic (3.96e-1)" "unprognostic (6.44e-3)" "unprognostic (6.37e-2)" "unprognostic (2.33e-1)" "unprognostic (8.82e-2)" "unprognostic (1.75e-1)" "unprognostic (6.61e-2)" "unprognostic (2.01e-2)" "unprognostic (7.04e-2)" "unprognostic (5.63e-2)" "unprognostic (3.37e-1)" "unprognostic (1.20e-1)" "unprognostic (6.10e-3)" "unprognostic (4.61e-2)" "unprognostic (6.01e-2)" "unprognostic (1.19e-1)" "unprognostic (5.66e-3)" "unprognostic (1.16e-2)" "unprognostic (9.95e-2)" "unprognostic (3.07e-1)" "unprognostic (1.71e-3)" "unprognostic (7.21e-2)" "unprognostic (3.37e-2)" "unprognostic (8.83e-2)" "unprognostic (1.73e-1)" "unprognostic (1.24e-1)" "unprognostic (1.49e-1)" "unprognostic (4.14e-2)" "unprognostic (8.46e-2)" "unprognostic (1.24e-1)" SERTAD4 DJ667H12.2 ENSG00000082497 "SERTA domain containing 4" Q9NUC0 1 210232796-210246631 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 3.6;Bergmann glia: 5.3;Brain excitatory neurons: 5.4;Brain inhibitory neurons: 8.5;Distal convoluted tubule cells: 3.5;Ependymal cells: 4.3;Extravillous trophoblasts: 8.1;Loop of henle epithelial cells: 5.3;Oligodendrocyte progenitor cells: 4.0;Oligodendrocytes: 6.7;Other brain neurons: 5.9;Papillary tip epithelial cells: 4.9;Renal collecting duct principal cells: 6.0;Respiratory deuterosomal cells: 3.1" "Cell type enhanced" "Detected in many" "fibroblast: 32.8" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 8.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 13.0" "Skeletal muscle - Fibroblasts, Testis - Spermatogonia, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027344, HPA028514" Uncertain Supported Nucleoplasm NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 35: Neurons - Synaptic function & neurogenesis" 15 Nucleoplasm "HPA027344: , HPA028514: " "unprognostic (3.89e-2)" "unprognostic (3.34e-2)" "unprognostic (5.05e-1)" "unprognostic (3.03e-1)" "unprognostic (4.54e-2)" "unprognostic (9.69e-2)" "unprognostic (1.94e-1)" "unprognostic (3.93e-1)" "potential prognostic favorable (4.11e-4)" "unprognostic (9.00e-3)" "unprognostic (1.98e-2)" "unprognostic (7.10e-2)" "unprognostic (2.84e-2)" "unprognostic (6.66e-2)" "unprognostic (5.71e-2)" "unprognostic (1.92e-1)" "unprognostic (1.26e-3)" "unprognostic (5.44e-2)" "unprognostic (6.42e-2)" "unprognostic (2.28e-1)" "unprognostic (2.11e-1)" "unprognostic (4.24e-2)" SERTM1 C13orf36 ENSG00000180440 "Serine rich and transmembrane domain containing 1" A2A2V5 13 36674020-36697839 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 29.2;endometrium 1: 22.3;fallopian tube: 39.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 25.6;Brain excitatory neurons: 16.9;Brain inhibitory neurons: 14.4;Choroid plexus epithelial cells: 19.1;Corticotrophs: 101.5;Epicardial cells: 18.2;Epididymal efferent duct ciliated cells: 24.8;Fallopian secretory cells: 14.8;Fallopian tube ciliated cells: 21.9;Mesothelial cells: 53.0;Oocytes: 13.8;Retinal bipolar cells: 23.6;Smooth muscle cells: 94.5" "Cell type enhanced" "Detected in many" "LAMP5-LHX6 and Chandelier: 71.9" "Cancer enhanced" "Detected in some" "Ovary Serous Cystadenocarcinoma (TCGA): 4.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Bone cancer: 5.2;lung cancer: 1.6;prostate cancer: 6.6;thyroid cancer: 2.0" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 1, Pancreas - Alpha cells, Pituitary gland - Corticotropes, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA054814, HPA070485" Enhanced Vesicles NA NA "Cluster 65: Brain - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 13 Vesicles "HPA054814: , HPA070485: " "unprognostic (1.50e-1)" "unprognostic (7.26e-2)" "unprognostic (1.70e-1)" "unprognostic (3.95e-2)" "unprognostic (6.41e-3)" SERTM2 LINC00890 ENSG00000260802 "Serine rich and transmembrane domain containing 2" A0A1B0GWG4 X 111511645-111522399 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "endometrium 1: 25.6;epididymis: 39.4;seminal vesicle: 71.2" "Cell type enriched" "Detected in some" 5 "Decidual stromal cells: 25.9" "Cell type enriched" "Detected in single" 5 "midbrain-derived inhibitory: 4.8" "Cancer enriched" "Detected in some" 5 "Kidney Chromophobe (TCGA): 20.6" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 18 "Neuroblastoma: 7.9" "Minor Salivary Gland - Plasma cells" "Region enhanced" "Detected in some" "basal ganglia: 2.8" "Low region specificity" "Detected in all" NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 108: Fibroblasts - ECM organization" "unprognostic (2.24e-1)" "unprognostic (9.64e-3)" "unprognostic (5.55e-2)" "unprognostic (2.74e-1)" SESN1 "PA26, SEST1" ENSG00000080546 "Sestrin 1" Q9Y6P5 6 108984309-109094846 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Myonuclei: 1614.7;Thymic myoid cells: 568.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "B-cells: 48.1;NK-cells: 59.1;T-cells: 74.6" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073659 Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 31: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 1 "Nucleoli fibrillar center" Nucleoplasm "HPA073659: " "unprognostic (3.90e-2)" "unprognostic (4.67e-2)" "unprognostic (1.59e-1)" "unprognostic (3.38e-3)" "unprognostic (8.50e-3)" "unprognostic (2.72e-1)" "unprognostic (1.61e-1)" "unprognostic (2.54e-1)" "potential prognostic favorable (5.49e-4)" "unprognostic (1.37e-1)" "validated prognostic favorable (6.05e-7)" "validated prognostic favorable (6.15e-4)" "unprognostic (3.77e-3)" "unprognostic (2.90e-1)" "unprognostic (2.25e-2)" "unprognostic (1.22e-2)" "unprognostic (1.02e-1)" "unprognostic (1.72e-1)" "unprognostic (1.71e-2)" "unprognostic (8.25e-2)" "unprognostic (5.36e-2)" "potential prognostic favorable (9.97e-4)" "unprognostic (1.18e-1)" "unprognostic (5.95e-3)" "unprognostic (1.14e-1)" "unprognostic (1.48e-1)" "unprognostic (6.28e-2)" "unprognostic (2.34e-1)" "unprognostic (3.50e-1)" "unprognostic (1.26e-2)" "unprognostic (3.64e-1)" SESN2 "DKFZp761M0212, HI95, SES2, SEST2" ENSG00000130766 "Sestrin 2" P58004 1 28259518-28282491 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 6.8;Brain inhibitory neurons: 6.4;Choroid plexus epithelial cells: 11.8;Distal convoluted tubule cells: 7.8;Loop of henle epithelial cells: 9.9;Microglia: 8.5;Oligodendrocyte progenitor cells: 6.9;Other brain neurons: 5.3;Papillary tip epithelial cells: 10.8;Podocytes: 12.1;Proximal tubule cells: 47.1;Renal collecting duct intercalated cells: 6.3;Renal collecting duct principal cells: 8.8;Renal connecting tubule cells: 10.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018191 Uncertain Approved Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 70: Non-specific - Protein processing" "Cluster 38: Sub-cortical - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 88: Proximal tubular cells - Transmembrane transport" 18 Cytosol "HPA018191: " "unprognostic (7.67e-2)" "unprognostic (8.19e-2)" "unprognostic (3.12e-1)" "unprognostic (1.30e-2)" "unprognostic (2.95e-2)" "unprognostic (1.34e-1)" "unprognostic (1.72e-1)" "unprognostic (3.42e-1)" "unprognostic (7.00e-2)" "unprognostic (3.44e-2)" "unprognostic (3.79e-2)" "unprognostic (7.73e-2)" "unprognostic (3.30e-1)" "potential prognostic unfavorable (7.48e-4)" "unprognostic (4.19e-2)" "unprognostic (1.34e-1)" "unprognostic (4.61e-2)" "unprognostic (6.76e-3)" "unprognostic (1.79e-1)" "unprognostic (7.53e-2)" "unprognostic (1.64e-1)" "unprognostic (4.66e-2)" "unprognostic (6.95e-2)" "unprognostic (9.01e-3)" "unprognostic (7.81e-2)" "unprognostic (1.67e-1)" "unprognostic (3.68e-3)" "unprognostic (1.89e-1)" "unprognostic (2.55e-1)" "unprognostic (1.42e-1)" "unprognostic (6.24e-3)" SESN3 "MGC29667, SEST3" ENSG00000149212 "Sestrin 3" P58005 11 95165513-95232541 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 54.0" "Cell type enhanced" "Detected in many" "B-cells: 346.9;Early spermatids: 803.7;Late primary spermatocytes: 363.7;Late spermatids: 825.6;Retinal pigment epithelial cells: 456.1" "Cell type enhanced" "Detected in all" "pericyte: 702.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in many" 5 "testis cancer: 102.2" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037935 Approved Nucleoplasm,Cytosol NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 73: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 1 Nucleoplasm Cytosol "HPA037935: " "unprognostic (1.39e-1)" "unprognostic (3.72e-2)" "unprognostic (9.48e-2)" "unprognostic (5.64e-2)" "unprognostic (7.53e-2)" "unprognostic (2.15e-2)" "unprognostic (9.66e-2)" "unprognostic (2.84e-3)" "unprognostic (1.06e-1)" "unprognostic (8.53e-2)" "unprognostic (1.73e-2)" "unprognostic (6.11e-2)" "unprognostic (1.84e-2)" "unprognostic (2.78e-1)" "unprognostic (1.42e-1)" "unprognostic (1.23e-2)" "unprognostic (2.69e-1)" "unprognostic (1.17e-2)" "unprognostic (1.18e-1)" "unprognostic (2.43e-1)" "unprognostic (1.33e-2)" "unprognostic (4.76e-3)" "unprognostic (3.38e-1)" "unprognostic (4.52e-2)" "unprognostic (3.80e-2)" "unprognostic (1.42e-1)" "unprognostic (8.14e-2)" "unprognostic (1.15e-1)" "unprognostic (1.15e-1)" "unprognostic (1.02e-2)" "unprognostic (1.51e-2)" SESTD1 "DKFZp434O0515, Solo" ENSG00000187231 "SEC14 and spectrin domain containing 1" Q86VW0 2 179101678-179264832 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial glandular cells: 950.1;Endometrial luminal cells: 756.5;monocytes: 581.9;Retinal horizontal cells: 803.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058236, HPA077408" Approved Enhanced "Intermediate filaments" NA Yes "Cluster 40: Monocytes - Innate immune response" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 51: Secretory epithelial cells - Mixed function" 15 "Intermediate filaments" "HPA058236: , HPA077408: " "potential prognostic favorable (8.08e-4)" "unprognostic (7.49e-2)" "unprognostic (1.49e-1)" "unprognostic (6.53e-2)" "unprognostic (2.62e-1)" "unprognostic (1.09e-1)" "unprognostic (6.08e-2)" "unprognostic (5.24e-2)" "unprognostic (1.64e-1)" "unprognostic (1.98e-1)" "potential prognostic favorable (2.40e-8)" "unprognostic (3.91e-3)" "unprognostic (5.00e-2)" "potential prognostic unfavorable (3.09e-4)" "unprognostic (1.57e-2)" "unprognostic (3.76e-2)" "unprognostic (2.97e-1)" "unprognostic (2.74e-2)" "unprognostic (2.15e-1)" "unprognostic (1.18e-1)" "unprognostic (3.87e-2)" "unprognostic (9.11e-3)" "unprognostic (7.33e-2)" "unprognostic (7.87e-2)" "unprognostic (3.57e-1)" "unprognostic (5.13e-2)" "unprognostic (8.46e-2)" "unprognostic (5.60e-2)" "unprognostic (6.64e-2)" "unprognostic (3.63e-2)" "unprognostic (2.47e-1)" SET "2PP2A, IGAAD, IPP2A2, PHAPII, TAF-I, TAF-IBETA" ENSG00000119335 "SET nuclear proto-oncogene" Q01105 9 128683424-128696400 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Chaperone, DNA-binding" "Cancer-related genes, Disease variant, Intellectual disability, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "CAB005232, HPA063683" Supported Enhanced "Nucleoplasm,Lipid droplets" NA NA 1700000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 61: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 17: Non-specific - RNA processing" 65 Nucleoplasm "Lipid droplets" "CAB005232: , HPA063683: " "unprognostic (1.18e-3)" "unprognostic (2.49e-1)" "unprognostic (5.23e-2)" "unprognostic (1.44e-1)" "unprognostic (1.32e-1)" "unprognostic (2.10e-3)" "unprognostic (2.86e-2)" "unprognostic (1.30e-2)" "unprognostic (1.40e-2)" "unprognostic (1.53e-1)" "potential prognostic favorable (2.55e-6)" "unprognostic (4.25e-3)" "unprognostic (1.95e-1)" "validated prognostic unfavorable (1.66e-4)" "validated prognostic unfavorable (3.85e-6)" "unprognostic (1.17e-2)" "unprognostic (3.54e-3)" "unprognostic (2.19e-1)" "unprognostic (6.50e-3)" "unprognostic (4.03e-1)" "unprognostic (5.08e-2)" "unprognostic (1.05e-2)" "unprognostic (2.28e-1)" "unprognostic (4.08e-2)" "unprognostic (1.26e-1)" "unprognostic (2.55e-1)" "unprognostic (1.22e-1)" "unprognostic (1.21e-2)" "unprognostic (2.62e-1)" "unprognostic (1.31e-1)" "unprognostic (5.79e-2)" SETBP1 "KIAA0437, SEB" ENSG00000152217 "SET binding protein 1" Q9Y6X0 18 44680173-45068510 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" DNA-binding "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 589.4;Fibro-adipogenic progenitors: 597.9;Loop of henle epithelial cells: 698.1;Myonuclei: 756.6;Pituitary stem cells: 642.4;Proximal tubule cells: 841.3;Renal collecting duct intercalated cells: 789.3;Renal connecting tubule cells: 1079.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 2.9;plasmacytoid DC: 2.7" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Myeloma: 14.2" "Adrenal gland - Fibroblasts, Lung - Fibroblasts_1, Prostate - Fibroblasts, Spleen - B-cells (Spleen), Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049022, HPA057259" Uncertain Supported "Nucleoplasm,Nuclear membrane,Nuclear bodies,Cytosol" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 31: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 108: Fibroblasts - ECM organization" 9 Nucleoplasm "Nuclear membrane, Nuclear bodies, Cytosol" "HPA049022: , HPA057259: " "unprognostic (7.87e-2)" "unprognostic (9.13e-2)" "unprognostic (1.63e-1)" "unprognostic (1.26e-1)" "unprognostic (6.36e-2)" "unprognostic (4.51e-2)" "unprognostic (2.64e-3)" "unprognostic (1.43e-1)" "unprognostic (4.91e-2)" "validated prognostic favorable (5.78e-7)" "validated prognostic favorable (1.78e-7)" "unprognostic (1.37e-1)" "unprognostic (3.99e-2)" "unprognostic (1.71e-2)" "unprognostic (3.04e-2)" "unprognostic (3.74e-2)" "unprognostic (3.06e-2)" "unprognostic (1.62e-1)" "unprognostic (5.09e-2)" "unprognostic (7.53e-2)" "unprognostic (4.54e-3)" "unprognostic (2.02e-1)" "unprognostic (1.05e-1)" "unprognostic (4.62e-3)" "unprognostic (1.92e-1)" "unprognostic (9.66e-3)" "unprognostic (3.06e-1)" "unprognostic (1.35e-2)" "unprognostic (1.82e-1)" SETD1A "KIAA0339, KMT2F, Set1, SET1A" ENSG00000099381 "SET domain containing 1A, histone lysine methyltransferase" O15047 16 30957754-30984664 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, Transcription, Transcription regulation" "Activator, Chromatin regulator, Methyltransferase, RNA-binding, Transferase" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "HPA020646, HPA058376" Enhanced Supported "Nuclear speckles" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 54: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 36 "Nuclear speckles" "HPA020646: , HPA058376: " "unprognostic (2.92e-1)" "unprognostic (7.00e-2)" "unprognostic (3.83e-1)" "unprognostic (4.38e-2)" "unprognostic (1.54e-1)" "unprognostic (1.76e-1)" "unprognostic (2.56e-1)" "unprognostic (2.55e-1)" "unprognostic (5.99e-2)" "unprognostic (2.05e-1)" "unprognostic (3.73e-2)" "unprognostic (3.62e-2)" "unprognostic (1.11e-1)" "unprognostic (2.14e-3)" "unprognostic (3.21e-2)" "unprognostic (2.85e-1)" "unprognostic (1.07e-1)" "unprognostic (3.40e-1)" "unprognostic (1.15e-2)" "unprognostic (1.13e-1)" "unprognostic (1.07e-1)" "unprognostic (6.14e-2)" "unprognostic (6.77e-3)" "unprognostic (8.20e-2)" "unprognostic (2.75e-2)" "unprognostic (2.19e-1)" "unprognostic (1.66e-1)" "unprognostic (1.29e-1)" "unprognostic (2.13e-1)" "unprognostic (4.99e-2)" "unprognostic (2.85e-2)" SETD1B "KIAA1076, KMT2G, Set1B" ENSG00000139718 "SET domain containing 1B, histone lysine methyltransferase" Q9UPS6 12 121804009-121832656 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Methyltransferase, RNA-binding, Transferase" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 73.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021667, HPA059412" Approved Supported Nucleoplasm NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 15: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 9 Nucleoplasm "HPA021667: , HPA059412: " "unprognostic (7.05e-3)" "unprognostic (3.43e-1)" "unprognostic (6.24e-2)" "unprognostic (2.81e-2)" "unprognostic (5.13e-2)" "unprognostic (6.68e-2)" "unprognostic (4.15e-1)" "unprognostic (3.83e-1)" "unprognostic (2.91e-2)" "unprognostic (5.06e-2)" "unprognostic (9.47e-3)" "unprognostic (1.40e-2)" "unprognostic (3.25e-1)" "unprognostic (1.09e-2)" "unprognostic (1.72e-1)" "unprognostic (2.00e-1)" "unprognostic (1.07e-1)" "unprognostic (4.68e-1)" "unprognostic (2.82e-3)" "unprognostic (9.77e-2)" "unprognostic (1.86e-1)" "unprognostic (7.93e-2)" "unprognostic (2.54e-2)" "unprognostic (2.68e-1)" "unprognostic (6.27e-2)" "unprognostic (8.54e-3)" "unprognostic (7.68e-2)" "unprognostic (3.42e-1)" "unprognostic (4.19e-1)" "unprognostic (5.07e-2)" "unprognostic (2.47e-1)" SETD2 "FLJ23184, HIF-1, HYPB, KIAA1732, KMT3A" ENSG00000181555 "SET domain containing 2, histone lysine methyltransferase" Q9BYW2 3 47016428-47164113 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Antiviral defense, Differentiation, DNA damage, DNA repair, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, Methyltransferase, Transferase" "Autism spectrum disorder, Cancer-related genes, Disease variant, Intellectual disability, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042451 Approved Approved "Nuclear speckles,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 25 "Nuclear speckles" Cytosol "HPA042451: " "unprognostic (1.13e-1)" "unprognostic (6.72e-2)" "unprognostic (1.76e-1)" "unprognostic (2.58e-1)" "unprognostic (4.34e-2)" "unprognostic (4.03e-2)" "unprognostic (4.38e-2)" "unprognostic (4.28e-2)" "unprognostic (7.98e-3)" "unprognostic (6.70e-2)" "potential prognostic favorable (2.19e-7)" "unprognostic (2.12e-3)" "unprognostic (6.55e-2)" "unprognostic (1.38e-1)" "unprognostic (1.42e-1)" "unprognostic (1.21e-1)" "unprognostic (1.54e-1)" "unprognostic (1.73e-1)" "unprognostic (3.69e-1)" "unprognostic (8.06e-2)" "unprognostic (1.36e-2)" "unprognostic (3.47e-2)" "unprognostic (3.99e-2)" "unprognostic (9.85e-2)" "unprognostic (7.07e-3)" "unprognostic (3.31e-2)" "unprognostic (8.74e-2)" "unprognostic (2.20e-1)" "unprognostic (3.54e-1)" "unprognostic (1.48e-3)" "unprognostic (1.18e-1)" SETD3 "C14orf154, FLJ23027" ENSG00000183576 "SET domain containing 3, actin histidine methyltransferase" Q86TU7 14 99397748-99480889 "Enzymes, Predicted intracellular proteins" "Actin-binding, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 311.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Spleen - Endothelial cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003591, HPA003639" Approved Approved Mitochondria NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 2 Mitochondria "HPA003591: , HPA003639: " "unprognostic (3.46e-2)" "unprognostic (5.18e-1)" "unprognostic (2.35e-1)" "unprognostic (4.44e-3)" "unprognostic (8.19e-2)" "unprognostic (2.95e-1)" "unprognostic (3.62e-1)" "unprognostic (8.88e-3)" "unprognostic (4.17e-3)" "unprognostic (9.70e-3)" "potential prognostic favorable (7.68e-10)" "unprognostic (4.57e-3)" "unprognostic (1.00e-2)" "unprognostic (5.15e-3)" "unprognostic (1.34e-1)" "unprognostic (1.94e-1)" "unprognostic (3.07e-2)" "unprognostic (3.36e-1)" "unprognostic (2.96e-1)" "unprognostic (1.70e-1)" "unprognostic (1.07e-3)" "unprognostic (1.15e-1)" "unprognostic (8.67e-2)" "unprognostic (1.32e-2)" "unprognostic (3.29e-1)" "unprognostic (1.97e-3)" "unprognostic (1.17e-1)" "unprognostic (6.83e-2)" "unprognostic (1.34e-1)" "unprognostic (4.58e-1)" "unprognostic (2.32e-1)" SETD4 "C21orf18, C21orf27" ENSG00000185917 "SET domain containing 4" Q9NVD3 21 36034541-36079389 "Enzymes, Predicted intracellular proteins" "Inflammatory response" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 114.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA024073, HPA035405" Approved Approved "Nuclear speckles" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 31: Non-specific - Transcription" "Cluster 47: Leukemia - Hemostasis" "Cluster 7: Non-specific - Transcription" "Nuclear speckles" "HPA024073: , HPA035405: " "unprognostic (4.63e-2)" "unprognostic (6.10e-2)" "unprognostic (6.99e-2)" "unprognostic (1.12e-1)" "unprognostic (3.49e-2)" "unprognostic (3.58e-2)" "unprognostic (1.44e-1)" "unprognostic (3.83e-3)" "unprognostic (3.85e-2)" "unprognostic (3.63e-1)" "unprognostic (2.40e-2)" "unprognostic (1.26e-1)" "unprognostic (1.38e-2)" "unprognostic (7.27e-2)" "unprognostic (3.21e-2)" "unprognostic (1.67e-1)" "unprognostic (1.33e-2)" "unprognostic (8.98e-3)" "unprognostic (1.56e-2)" "potential prognostic favorable (9.62e-4)" "unprognostic (3.41e-1)" "unprognostic (7.97e-3)" "unprognostic (1.61e-2)" "unprognostic (1.33e-2)" "unprognostic (2.04e-2)" "unprognostic (5.78e-2)" "unprognostic (1.59e-3)" "unprognostic (1.65e-1)" "unprognostic (1.71e-1)" "unprognostic (9.29e-2)" "unprognostic (4.84e-2)" SETD5 "FLJ10707, SETD5A" ENSG00000168137 "SET domain containing 5" Q9C0A6 3 9397615-9479240 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Transferase" "Autism, Autism spectrum disorder, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017093, HPA035574" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 18: Adrenal cortex cells - Steroidogensis" 4 Nucleoplasm Cytosol "CAB017093: , HPA035574: " "unprognostic (2.66e-2)" "unprognostic (8.81e-3)" "unprognostic (1.79e-2)" "unprognostic (6.52e-2)" "unprognostic (4.70e-2)" "unprognostic (2.40e-2)" "unprognostic (1.14e-1)" "unprognostic (2.26e-2)" "unprognostic (1.30e-1)" "unprognostic (3.49e-3)" "unprognostic (2.50e-1)" "unprognostic (1.78e-2)" "unprognostic (2.14e-1)" "unprognostic (3.92e-3)" "unprognostic (4.10e-1)" "unprognostic (2.63e-1)" "unprognostic (3.41e-2)" "unprognostic (1.40e-1)" "unprognostic (2.20e-2)" "unprognostic (1.60e-1)" "unprognostic (1.65e-1)" "unprognostic (2.55e-1)" "unprognostic (9.03e-3)" "unprognostic (2.08e-2)" "unprognostic (2.28e-3)" "unprognostic (1.41e-2)" "unprognostic (2.97e-1)" "unprognostic (3.98e-2)" "unprognostic (1.72e-1)" "unprognostic (3.42e-2)" "unprognostic (1.58e-1)" SETD6 FLJ21148 ENSG00000103037 "SET domain containing 6, protein lysine methyltransferase" Q8TBK2 16 58515479-58523842 "Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041481, HPA053546" Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 64: Non-specific - Transcription" "Cluster 35: Non-specific - DNA binding" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 1 Nucleoplasm Cytosol "HPA041481: , HPA053546: " "unprognostic (1.73e-1)" "unprognostic (1.34e-1)" "unprognostic (2.81e-1)" "unprognostic (3.26e-1)" "unprognostic (1.90e-1)" "unprognostic (7.77e-2)" "unprognostic (6.76e-2)" "unprognostic (3.66e-3)" "unprognostic (6.33e-2)" "unprognostic (1.26e-1)" "potential prognostic unfavorable (3.33e-5)" "unprognostic (4.24e-2)" "unprognostic (1.95e-2)" "unprognostic (2.80e-2)" "unprognostic (3.83e-1)" "unprognostic (6.94e-2)" "unprognostic (2.93e-1)" "unprognostic (3.33e-1)" "unprognostic (2.28e-2)" "unprognostic (4.92e-2)" "unprognostic (3.77e-1)" "unprognostic (3.64e-2)" "unprognostic (4.42e-2)" "unprognostic (1.77e-2)" "unprognostic (4.65e-1)" "unprognostic (1.40e-1)" "unprognostic (1.20e-3)" "unprognostic (2.35e-1)" "unprognostic (3.71e-2)" "unprognostic (1.71e-2)" "unprognostic (3.16e-2)" SETD7 "KIAA1717, KMT7, SET7, SET7/9, Set9" ENSG00000145391 "SET domain containing 7, histone lysine methyltransferase" Q8WTS6 4 139495941-139606699 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Prostatic glandular cells: 129.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Spleen - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058111 Enhanced Enhanced "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 45 "Nucleoli, Nucleoli rim" "Mitotic chromosome" "HPA058111: " "unprognostic (3.97e-2)" "unprognostic (6.04e-3)" "unprognostic (3.10e-1)" "unprognostic (3.61e-3)" "unprognostic (1.56e-1)" "unprognostic (8.33e-2)" "unprognostic (2.85e-1)" "unprognostic (2.72e-1)" "unprognostic (4.11e-2)" "unprognostic (2.70e-2)" "potential prognostic favorable (1.41e-4)" "unprognostic (2.47e-3)" "unprognostic (1.67e-1)" "unprognostic (6.89e-2)" "unprognostic (2.45e-3)" "unprognostic (4.42e-2)" "unprognostic (2.03e-2)" "unprognostic (1.98e-1)" "unprognostic (1.90e-1)" "unprognostic (4.33e-2)" "unprognostic (4.79e-2)" "unprognostic (1.05e-1)" "unprognostic (1.04e-1)" "unprognostic (1.25e-1)" "unprognostic (2.53e-1)" "unprognostic (2.21e-1)" "unprognostic (2.06e-2)" "unprognostic (1.06e-3)" "unprognostic (1.36e-1)" "unprognostic (3.07e-2)" "unprognostic (1.15e-1)" SETD9 "C5orf35, MGC33648" ENSG00000155542 "SET domain containing 9" Q8NE22 5 56909260-56925532 "Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 17.6" "Group enriched" "Detected in many" 9 "Early spermatids: 754.2;Late primary spermatocytes: 414.9;Late spermatids: 482.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 5.2" "Group enriched" "Detected in many" 4 "granulocytes: 5.2;monocytes: 3.2" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" HPA049936 Approved Nucleoplasm NA NA "Cluster 32: Basophils - Transcription" "Cluster 57: Testis - Spermatogenesis" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 2 Nucleoplasm "HPA049936: " "unprognostic (1.79e-2)" "unprognostic (9.25e-2)" "unprognostic (4.54e-2)" "unprognostic (4.82e-2)" "unprognostic (8.76e-3)" "unprognostic (2.83e-1)" "potential prognostic unfavorable (5.05e-4)" "unprognostic (1.90e-1)" "unprognostic (2.78e-1)" "unprognostic (1.12e-3)" "unprognostic (6.41e-3)" "unprognostic (1.20e-1)" "unprognostic (1.91e-1)" "unprognostic (1.56e-1)" "unprognostic (7.62e-2)" "unprognostic (2.99e-1)" "unprognostic (5.14e-1)" "unprognostic (5.74e-2)" "unprognostic (1.50e-1)" "unprognostic (2.15e-1)" "unprognostic (6.11e-2)" "unprognostic (2.12e-1)" "unprognostic (1.64e-2)" "unprognostic (3.08e-2)" "unprognostic (1.93e-1)" "unprognostic (1.23e-1)" "unprognostic (3.80e-1)" "unprognostic (5.59e-2)" "unprognostic (9.11e-2)" SETDB1 "ESET, KG1T, KIAA0067, KMT1E, TDRD21" ENSG00000143379 "SET domain bifurcated histone lysine methyltransferase 1" Q15047 1 150926263-150964744 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018142, HPA058484" Uncertain Supported Nucleoplasm,Vesicles Yes No "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 61: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" 48 Nucleoplasm Vesicles "HPA018142: , HPA058484: " "unprognostic (8.89e-2)" "unprognostic (1.40e-1)" "unprognostic (3.85e-2)" "unprognostic (1.39e-2)" "unprognostic (2.25e-1)" "unprognostic (2.40e-1)" "unprognostic (2.20e-1)" "potential prognostic favorable (7.02e-4)" "unprognostic (2.71e-1)" "unprognostic (1.41e-3)" "potential prognostic favorable (9.39e-6)" "unprognostic (6.63e-3)" "unprognostic (9.03e-2)" "unprognostic (2.50e-3)" "unprognostic (5.34e-2)" "unprognostic (1.34e-1)" "unprognostic (1.04e-2)" "unprognostic (1.79e-1)" "unprognostic (9.85e-2)" "unprognostic (1.23e-1)" "unprognostic (1.95e-1)" "unprognostic (4.32e-2)" "unprognostic (1.39e-1)" "unprognostic (4.59e-2)" "unprognostic (1.51e-2)" "unprognostic (1.86e-1)" "unprognostic (2.68e-2)" "unprognostic (3.14e-1)" "unprognostic (1.26e-1)" "unprognostic (5.71e-2)" "unprognostic (5.90e-2)" SETDB2 "C13orf4, CLLD8, CLLL8, KMT1F" ENSG00000136169 "SET domain bifurcated histone lysine methyltransferase 2" Q96T68 13 49444274-49495003 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Chromatin regulator, Developmental protein, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 109.5;Renal collecting duct intercalated cells: 106.3;Sertoli cells: 125.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012190, HPA071677" Approved Supported Nucleoplasm,Cytosol No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 19: Non-specific - Unknown function" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 3 Nucleoplasm Cytosol "CAB012190: , HPA071677: " "unprognostic (5.67e-2)" "unprognostic (3.94e-1)" "unprognostic (1.47e-1)" "unprognostic (9.66e-2)" "unprognostic (2.98e-1)" "unprognostic (3.50e-2)" "unprognostic (1.15e-1)" "unprognostic (4.06e-2)" "unprognostic (3.54e-2)" "unprognostic (1.63e-1)" "potential prognostic favorable (9.24e-6)" "unprognostic (4.05e-3)" "potential prognostic favorable (7.32e-7)" "unprognostic (6.40e-2)" "unprognostic (4.65e-2)" "potential prognostic favorable (7.41e-4)" "unprognostic (1.61e-1)" "unprognostic (1.72e-2)" "unprognostic (1.26e-1)" "unprognostic (3.39e-2)" "unprognostic (7.12e-2)" "unprognostic (2.89e-3)" "unprognostic (4.35e-2)" "unprognostic (3.42e-1)" "unprognostic (6.00e-2)" "unprognostic (5.77e-3)" "unprognostic (2.76e-1)" "unprognostic (2.30e-1)" "unprognostic (1.78e-1)" "unprognostic (3.25e-3)" "unprognostic (3.76e-2)" SETMAR metnase ENSG00000170364 "SET domain and mariner transposase fusion gene" Q53H47 3 4303332-4317265 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Chromatin regulator, DNA-binding, Endonuclease, Hydrolase, Methyltransferase, Multifunctional enzyme, Nuclease, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epicardial cells: 43.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts" HPA057999 Supported Nucleoli NA NA "Cluster 24: Non-specific - Transcription" "Cluster 75: Ovary - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 89: Adipocytes - Lipid metabolism" 6 Nucleoli "HPA057999: " "unprognostic (9.66e-2)" "potential prognostic unfavorable (8.11e-4)" "unprognostic (8.26e-2)" "unprognostic (3.03e-3)" "unprognostic (9.17e-2)" "unprognostic (1.80e-1)" "unprognostic (1.72e-1)" "unprognostic (5.87e-2)" "unprognostic (2.08e-1)" "unprognostic (1.12e-3)" "unprognostic (8.58e-3)" "unprognostic (7.39e-2)" "unprognostic (9.83e-2)" "potential prognostic unfavorable (1.40e-4)" "unprognostic (1.24e-1)" "unprognostic (5.51e-2)" "unprognostic (7.12e-2)" "unprognostic (3.10e-2)" "unprognostic (1.55e-2)" "unprognostic (7.05e-2)" "unprognostic (1.01e-2)" "unprognostic (3.08e-3)" "unprognostic (1.05e-1)" "unprognostic (6.52e-2)" "unprognostic (1.08e-3)" "unprognostic (1.14e-2)" "unprognostic (1.83e-1)" "unprognostic (3.46e-2)" "unprognostic (1.56e-1)" "unprognostic (2.88e-2)" "unprognostic (6.44e-2)" SETSIP SETP18 ENSG00000230667 "SET like protein" P0DME0 1 92074533-92075411 "Predicted intracellular proteins" "Differentiation, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Early spermatids: 1.6;Late primary spermatocytes: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA063683 Approved Supported "Nucleoplasm,Lipid droplets" NA NA "Cluster 9: Non-specific - Receptor signaling" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 3 Nucleoplasm "Lipid droplets" "HPA063683: " "potential prognostic unfavorable (8.43e-4)" SETX "ALS4, AOA2, KIAA0625, SCAR1, Sen1, STEX" ENSG00000107290 Senataxin Q7Z333 9 132261356-132354986 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Differentiation, DNA damage, DNA recombination, DNA repair, Neurogenesis, Spermatogenesis" "Helicase, Hydrolase" "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024105, HPA057269" Approved Supported "Nucleoplasm,Cytokinetic bridge" Yes No "Cluster 35: Neutrophils - Protein binding" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 69: Urothelial cells - Basic cellular functions" 10 Nucleoplasm "Cytokinetic bridge" "HPA024105: , HPA057269: " "unprognostic (3.28e-1)" "unprognostic (6.30e-2)" "unprognostic (3.35e-3)" "unprognostic (1.27e-1)" "unprognostic (1.31e-1)" "unprognostic (8.03e-3)" "unprognostic (1.61e-1)" "unprognostic (7.06e-3)" "unprognostic (3.90e-2)" "unprognostic (9.47e-3)" "potential prognostic favorable (5.60e-6)" "unprognostic (2.85e-3)" "unprognostic (2.82e-1)" "unprognostic (1.69e-1)" "unprognostic (2.06e-1)" "unprognostic (1.95e-1)" "unprognostic (5.08e-2)" "unprognostic (6.06e-2)" "unprognostic (1.47e-2)" "unprognostic (6.92e-3)" "unprognostic (4.25e-2)" "unprognostic (5.52e-2)" "unprognostic (5.18e-2)" "unprognostic (3.15e-1)" "unprognostic (4.55e-3)" "unprognostic (5.96e-2)" "unprognostic (2.69e-1)" "unprognostic (1.40e-1)" "unprognostic (3.14e-1)" "unprognostic (1.76e-2)" "unprognostic (2.02e-1)" SEZ6 ENSG00000063015 "Seizure related 6 homolog" Q53EL9 17 28954901-29006440 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 109.8" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 41.0;Brain inhibitory neurons: 69.9;Cone photoreceptor cells: 37.3;Lactotrophs: 20.1;Other brain neurons: 33.8;Pancreatic islet cells: 20.3;Retinal amacrine cells: 70.7;Retinal bipolar cells: 69.7;Retinal ganglion cells: 50.2;Retinal horizontal cells: 30.1;Thyrotrophs: 25.5" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 11 "Glioblastoma Multiforme (TCGA): 53.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 1.1;neutrophil: 2.0" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.0" "Cancer enhanced" "Detected in many" "lung cancer: 13.1;Neuroblastoma: 14.3;thyroid cancer: 21.0" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011777 Enhanced NA NA 180000 "Cluster 27: Cerebellum - Synaptic function" "Cluster 33: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 1 "HPA011777: " "unprognostic (4.47e-2)" "unprognostic (4.05e-2)" "unprognostic (3.53e-2)" "unprognostic (1.28e-2)" "unprognostic (1.31e-1)" "unprognostic (6.61e-2)" "unprognostic (3.32e-1)" "unprognostic (5.54e-3)" "unprognostic (2.29e-2)" "unprognostic (3.36e-2)" "unprognostic (3.91e-1)" SEZ6L ENSG00000100095 "Seizure related 6 homolog like" Q9BYH1 22 26169462-26383597 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 46.3" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 202.1;Brain excitatory neurons: 324.8;Brain inhibitory neurons: 170.8;Corticotrophs: 92.8;Gonadotrophs: 212.8;Oligodendrocyte progenitor cells: 849.9;Other brain neurons: 238.2;Pancreatic islet cells: 183.2;Retinal amacrine cells: 170.0;Retinal horizontal cells: 122.2" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in some" 4 "Glioblastoma Multiforme (TCGA): 26.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "intermediate monocyte: 5.9;myeloid DC: 5.7;non-classical monocyte: 5.4" "Group enriched" "Detected in many" 58 "dendritic cells: 5.7;monocytes: 5.9" "Group enriched" "Detected in some" 5 "Bone cancer: 23.7;lung cancer: 8.1;Neuroblastoma: 23.5" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Skin - Outer root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045135 Approved Vesicles NA NA 1500000 "Cluster 40: Monocytes - Innate immune response" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 1: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" Vesicles "HPA045135: " "unprognostic (6.00e-2)" "unprognostic (1.76e-1)" "unprognostic (1.55e-2)" "unprognostic (3.39e-2)" "unprognostic (1.30e-1)" "unprognostic (1.94e-1)" "potential prognostic favorable (8.40e-5)" "unprognostic (1.72e-1)" "unprognostic (2.68e-1)" "unprognostic (1.77e-1)" SEZ6L2 "FLJ90517, PSK-1" ENSG00000174938 "Seizure related 6 homolog like 2" Q6UXD5 16 29871159-29899550 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 99.0;pituitary gland: 88.0" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 138.1;Brain inhibitory neurons: 138.7;Corticotrophs: 223.9;Gonadotrophs: 128.3;Lactotrophs: 122.6;Neuroendocrine cells: 115.1;Other brain neurons: 175.8;Pancreatic islet cells: 288.7;Retinal amacrine cells: 141.6;Retinal bipolar cells: 157.5;Retinal ganglion cells: 127.5;Retinal horizontal cells: 128.2;Rod photoreceptor cells: 118.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enteroendocrine cells, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Alpha cells, Pituitary gland - Lactotropes, Prostate - Prostate glandular cells, Spleen - Fibroblasts_1, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064471 Enhanced NA NA 2100000 "Cluster 27: Cerebellum - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" "HPA064471: " "unprognostic (2.94e-2)" "unprognostic (3.17e-3)" "unprognostic (1.10e-1)" "potential prognostic unfavorable (2.21e-4)" "unprognostic (4.08e-2)" "unprognostic (2.54e-1)" "potential prognostic unfavorable (9.63e-4)" "unprognostic (4.79e-2)" "unprognostic (4.61e-2)" "unprognostic (1.38e-1)" "unprognostic (7.35e-3)" "unprognostic (7.36e-2)" "unprognostic (4.89e-2)" "unprognostic (2.24e-2)" "unprognostic (9.85e-3)" "unprognostic (8.53e-2)" "unprognostic (2.53e-1)" "unprognostic (1.96e-2)" "unprognostic (8.39e-3)" "unprognostic (1.10e-1)" "unprognostic (4.03e-1)" "unprognostic (1.39e-2)" "unprognostic (4.56e-2)" "unprognostic (1.04e-1)" "unprognostic (2.71e-1)" "potential prognostic unfavorable (1.59e-4)" "unprognostic (1.63e-1)" "unprognostic (1.16e-1)" "unprognostic (8.39e-2)" "unprognostic (1.20e-1)" "unprognostic (1.40e-1)" SF1 "ZCCHC25, ZFM1, ZNF162" ENSG00000168066 "Splicing factor 1" Q15637 11 64764606-64778786 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018883 Supported Supported Nucleoplasm NA NA 120000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 24: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 63 Nucleoplasm "HPA018883: " "unprognostic (1.83e-1)" "unprognostic (2.26e-1)" "unprognostic (3.23e-2)" "unprognostic (4.92e-3)" "unprognostic (2.38e-1)" "unprognostic (5.38e-1)" "unprognostic (2.10e-1)" "unprognostic (1.25e-1)" "unprognostic (2.40e-1)" "unprognostic (4.95e-2)" "potential prognostic favorable (2.74e-5)" "unprognostic (1.05e-3)" "unprognostic (3.03e-1)" "potential prognostic unfavorable (7.32e-6)" "unprognostic (2.02e-1)" "unprognostic (1.05e-1)" "potential prognostic unfavorable (7.34e-5)" "unprognostic (5.99e-2)" "unprognostic (2.05e-2)" "unprognostic (3.19e-2)" "unprognostic (9.84e-2)" "unprognostic (5.06e-2)" "unprognostic (1.25e-2)" "unprognostic (2.21e-1)" "unprognostic (4.67e-2)" "unprognostic (7.96e-2)" "unprognostic (6.06e-2)" "unprognostic (3.48e-1)" "unprognostic (1.80e-1)" "unprognostic (3.00e-1)" "unprognostic (1.87e-2)" SF3A1 "Prp21, PRPF21, SAP114, SF3a120" ENSG00000099995 "Splicing factor 3a subunit 1" Q15459 22 30331988-30356919 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 179.7;Neutrophils: 132.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000690, HPA030083" Enhanced Enhanced "Nucleoplasm,Nuclear speckles" NA NA 28000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 39: Testis - Nuclear processes" "Cluster 16: Non-specific - Transcription" "Cluster 66: Non-specific - Mitochondria" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 299 "Nucleoplasm, Nuclear speckles" "HPA000690: , HPA030083: " "unprognostic (6.11e-3)" "unprognostic (1.21e-1)" "unprognostic (2.26e-1)" "unprognostic (1.63e-2)" "unprognostic (2.26e-1)" "unprognostic (7.38e-2)" "unprognostic (2.21e-2)" "unprognostic (2.51e-1)" "unprognostic (2.85e-1)" "unprognostic (6.11e-3)" "validated prognostic favorable (4.12e-8)" "validated prognostic favorable (4.01e-6)" "unprognostic (3.80e-2)" "potential prognostic unfavorable (9.79e-4)" "unprognostic (4.55e-3)" "unprognostic (1.40e-1)" "unprognostic (1.65e-1)" "unprognostic (9.21e-2)" "unprognostic (1.30e-2)" "unprognostic (3.53e-2)" "unprognostic (3.30e-2)" "unprognostic (5.58e-2)" "unprognostic (9.72e-2)" "unprognostic (3.19e-1)" "unprognostic (1.53e-1)" "unprognostic (1.19e-1)" "unprognostic (5.99e-2)" "unprognostic (4.62e-1)" "unprognostic (5.13e-1)" "unprognostic (1.61e-2)" "unprognostic (1.72e-2)" SF3A2 "Prp11, PRPF11, SAP62, SF3a66" ENSG00000104897 "Splicing factor 3a subunit 2" Q15428 19 2236824-2248655 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 155.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042843, HPA049439" Enhanced Supported Nucleoplasm NA NA 11000 "Cluster 45: Eosinophils - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 23: Non-specific - Transcription" "Cluster 94: Gonadal somatic cells - Mixed function" 226 Nucleoplasm "HPA042843: , HPA049439: " "unprognostic (1.38e-1)" "unprognostic (8.79e-2)" "unprognostic (7.82e-2)" "unprognostic (2.28e-1)" "unprognostic (1.80e-1)" "unprognostic (2.34e-1)" "unprognostic (6.79e-2)" "unprognostic (1.88e-2)" "unprognostic (6.66e-2)" "unprognostic (2.68e-1)" "unprognostic (3.83e-2)" "unprognostic (2.52e-1)" "unprognostic (7.57e-2)" "validated prognostic unfavorable (2.65e-5)" "validated prognostic unfavorable (4.25e-5)" "unprognostic (1.42e-2)" "unprognostic (3.88e-2)" "unprognostic (5.75e-2)" "unprognostic (9.89e-2)" "unprognostic (2.39e-2)" "unprognostic (1.48e-2)" "unprognostic (4.37e-3)" "unprognostic (2.41e-3)" "unprognostic (1.26e-1)" "unprognostic (2.05e-1)" "unprognostic (2.29e-2)" "unprognostic (2.66e-1)" "unprognostic (3.12e-2)" "unprognostic (5.36e-2)" "unprognostic (4.29e-2)" "unprognostic (1.74e-2)" SF3A3 "PRP9, PRPF9, SAP61, SF3a60" ENSG00000183431 "Splicing factor 3a subunit 3" Q12874 1 37956975-37990075 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 331.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032054, HPA032055" Supported Supported "Nucleoplasm,Nuclear speckles" NA NA 78000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 37: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 110 "Nuclear speckles" Nucleoplasm "HPA032054: , HPA032055: " "unprognostic (9.54e-2)" "unprognostic (2.52e-1)" "unprognostic (3.72e-3)" "unprognostic (9.40e-2)" "unprognostic (8.53e-2)" "unprognostic (1.54e-1)" "unprognostic (1.97e-2)" "unprognostic (2.31e-3)" "unprognostic (2.44e-1)" "unprognostic (4.63e-2)" "potential prognostic favorable (2.82e-4)" "unprognostic (3.14e-2)" "unprognostic (2.67e-1)" "validated prognostic unfavorable (3.95e-10)" "validated prognostic unfavorable (1.20e-4)" "unprognostic (2.47e-1)" "unprognostic (3.07e-2)" "unprognostic (1.26e-2)" "unprognostic (1.18e-1)" "unprognostic (9.05e-2)" "unprognostic (2.77e-2)" "unprognostic (2.77e-1)" "unprognostic (3.73e-1)" "unprognostic (9.48e-2)" "unprognostic (6.06e-3)" "unprognostic (4.23e-2)" "unprognostic (7.20e-2)" "unprognostic (1.63e-1)" "unprognostic (5.97e-2)" "unprognostic (1.22e-1)" "unprognostic (5.12e-2)" SF3B1 "Hsh155, Prp10, PRPF10, SAP155, SF3b155" ENSG00000115524 "Splicing factor 3b subunit 1" O75533 2 197388515-197435079 "Cancer-related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing, mRNA splicing" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050275 Approved Enhanced "Nuclear speckles" NA NA 140000 "Cluster 33: Non-specific - ATP binding" "Cluster 49: Non-specific - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 17: Non-specific - RNA processing" 300 "Nuclear speckles" "HPA050275: " "unprognostic (1.39e-1)" "unprognostic (1.43e-1)" "unprognostic (1.51e-1)" "unprognostic (1.63e-1)" "unprognostic (1.17e-1)" "unprognostic (1.67e-2)" "unprognostic (8.43e-2)" "unprognostic (2.21e-2)" "unprognostic (3.04e-3)" "unprognostic (4.70e-2)" "validated prognostic favorable (5.80e-4)" "validated prognostic favorable (5.48e-4)" "unprognostic (5.38e-3)" "potential prognostic unfavorable (1.44e-5)" "unprognostic (3.52e-1)" "unprognostic (3.06e-1)" "unprognostic (1.15e-1)" "unprognostic (9.81e-2)" "unprognostic (1.21e-1)" "unprognostic (1.42e-1)" "unprognostic (2.03e-1)" "unprognostic (7.06e-2)" "unprognostic (5.77e-2)" "unprognostic (2.23e-2)" "unprognostic (7.84e-2)" "unprognostic (2.18e-2)" "unprognostic (1.35e-2)" "unprognostic (1.69e-1)" "unprognostic (1.21e-1)" "unprognostic (2.61e-1)" "unprognostic (2.42e-3)" SF3B2 "Cus1, SAP145, SF3b1, SF3b145" ENSG00000087365 "Splicing factor 3b subunit 2" Q13435 11 66050729-66069308 "Disease related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 461.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045028 Supported Enhanced "Nuclear speckles" NA NA 25000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 11: White matter - Signal transduction" "Cluster 24: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 200 "Nuclear speckles" "HPA045028: " "unprognostic (2.24e-1)" "unprognostic (1.76e-1)" "unprognostic (4.31e-1)" "unprognostic (1.27e-1)" "unprognostic (6.93e-2)" "unprognostic (2.27e-1)" "unprognostic (8.09e-2)" "unprognostic (2.59e-3)" "unprognostic (1.66e-2)" "potential prognostic unfavorable (7.30e-5)" "unprognostic (2.00e-2)" "unprognostic (9.24e-3)" "unprognostic (4.86e-2)" "potential prognostic unfavorable (3.52e-5)" "unprognostic (4.60e-3)" "unprognostic (3.88e-3)" "potential prognostic unfavorable (4.76e-5)" "unprognostic (4.48e-2)" "unprognostic (3.75e-2)" "unprognostic (2.12e-1)" "unprognostic (1.69e-1)" "unprognostic (2.39e-2)" "potential prognostic unfavorable (1.44e-4)" "unprognostic (3.14e-1)" "unprognostic (3.65e-1)" "unprognostic (3.33e-1)" "unprognostic (1.72e-1)" "unprognostic (5.44e-2)" "unprognostic (6.74e-2)" "unprognostic (2.03e-2)" "unprognostic (9.22e-2)" SF3B3 "KIAA0017, RSE1, SAP130, SF3b130" ENSG00000189091 "Splicing factor 3b subunit 3" Q15393 16 70523791-70577670 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 5 "Esophageal apical cells: 772.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041134, HPA042986" Supported Supported "Nucleoplasm,Nucleoli,Nucleoli rim" No No 77000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 84: Apical squamous epithelium - Cornification" 231 "Nucleoplasm, Nucleoli, Nucleoli rim" "HPA041134: , HPA042986: " "unprognostic (2.06e-1)" "unprognostic (8.95e-2)" "unprognostic (1.49e-1)" "unprognostic (2.73e-3)" "unprognostic (6.23e-2)" "unprognostic (9.90e-2)" "unprognostic (1.88e-1)" "unprognostic (2.83e-2)" "unprognostic (4.44e-1)" "unprognostic (6.08e-2)" "potential prognostic favorable (2.67e-5)" "unprognostic (3.59e-2)" "unprognostic (2.54e-1)" "unprognostic (5.36e-3)" "unprognostic (7.46e-2)" "unprognostic (9.88e-2)" "potential prognostic unfavorable (7.57e-4)" "unprognostic (1.91e-1)" "unprognostic (2.29e-1)" "unprognostic (4.98e-2)" "unprognostic (2.77e-2)" "unprognostic (1.91e-3)" "unprognostic (1.75e-2)" "unprognostic (1.38e-1)" "unprognostic (1.00e-2)" "unprognostic (2.58e-1)" "unprognostic (1.02e-1)" "unprognostic (2.17e-1)" "unprognostic (1.62e-1)" "unprognostic (5.56e-3)" "unprognostic (1.86e-1)" SF3B4 "Hsh49, SAP49, SF3b49" ENSG00000143368 "Splicing factor 3b subunit 4" Q15427 1 149923317-149927803 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 117.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028578, HPA064660" Approved Approved "Nuclear speckles" NA NA 140000 "Cluster 25: Non-specific - Unknown function" "Cluster 54: Non-specific - Ribosome" "Cluster 16: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 153 "Nuclear speckles" "HPA028578: , HPA064660: " "unprognostic (1.64e-1)" "unprognostic (8.71e-2)" "unprognostic (1.40e-1)" "unprognostic (8.23e-2)" "unprognostic (1.02e-1)" "unprognostic (2.05e-1)" "unprognostic (4.23e-1)" "unprognostic (4.90e-2)" "unprognostic (1.93e-1)" "unprognostic (2.72e-2)" "unprognostic (1.87e-2)" "unprognostic (7.01e-3)" "unprognostic (3.58e-3)" "potential prognostic unfavorable (5.20e-5)" "unprognostic (2.33e-3)" "unprognostic (9.21e-3)" "potential prognostic unfavorable (1.87e-4)" "unprognostic (1.98e-2)" "unprognostic (5.93e-2)" "unprognostic (2.02e-1)" "unprognostic (2.07e-1)" "unprognostic (3.79e-2)" "unprognostic (1.22e-1)" "unprognostic (1.54e-1)" "unprognostic (2.16e-2)" "unprognostic (8.44e-2)" "unprognostic (8.87e-2)" "unprognostic (1.39e-1)" "unprognostic (5.39e-2)" "unprognostic (3.79e-2)" "unprognostic (3.92e-2)" SF3B5 "MGC3133, SF3b10, Ysf3" ENSG00000169976 "Splicing factor 3b subunit 5" Q9BWJ5 6 144094884-144095573 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 564.1;Esophageal suprabasal cells: 671.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054408 Approved Enhanced Nucleoplasm NA NA 6400 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 97: Non-specific - Cellular respiration" 104 Nucleoplasm "HPA054408: " "unprognostic (5.12e-3)" "unprognostic (1.23e-2)" "unprognostic (1.58e-1)" "unprognostic (3.10e-1)" "unprognostic (2.38e-1)" "unprognostic (2.33e-2)" "unprognostic (3.11e-2)" "unprognostic (1.65e-1)" "unprognostic (7.61e-3)" "unprognostic (1.85e-3)" "unprognostic (1.92e-2)" "unprognostic (8.82e-2)" "unprognostic (4.06e-3)" "validated prognostic unfavorable (2.29e-4)" "validated prognostic unfavorable (4.50e-6)" "unprognostic (9.17e-2)" "unprognostic (8.99e-2)" "unprognostic (3.03e-2)" "unprognostic (4.05e-2)" "unprognostic (7.89e-2)" "unprognostic (4.00e-1)" "unprognostic (7.85e-3)" "unprognostic (1.29e-1)" "unprognostic (3.76e-2)" "unprognostic (4.89e-3)" "unprognostic (2.60e-1)" "potential prognostic favorable (7.03e-4)" "unprognostic (1.52e-1)" "unprognostic (1.21e-1)" "unprognostic (7.43e-2)" "unprognostic (4.99e-2)" SF3B6 "CGI-110, Ht006, P14, SAP14a, SF3B14a" ENSG00000115128 "Splicing factor 3b subunit 6" Q9Y3B4 2 24067586-24076373 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1245.4;Esophageal suprabasal cells: 817.2;Gastric progenitor cells: 651.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034829, HPA034830" Enhanced Supported Nucleoplasm NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 85: Squamous epithelial cells - Keratinization" 101 Nucleoplasm "HPA034829: , HPA034830: " "unprognostic (1.79e-2)" "unprognostic (3.08e-1)" "unprognostic (9.51e-2)" "unprognostic (4.68e-2)" "unprognostic (2.09e-1)" "unprognostic (8.24e-2)" "unprognostic (6.97e-2)" "unprognostic (2.15e-3)" "unprognostic (4.26e-2)" "unprognostic (1.54e-2)" "unprognostic (8.31e-2)" "potential prognostic unfavorable (2.33e-5)" "potential prognostic unfavorable (4.95e-6)" "unprognostic (4.77e-3)" "unprognostic (1.32e-2)" "unprognostic (1.38e-2)" "unprognostic (5.88e-2)" "unprognostic (1.51e-1)" "unprognostic (9.99e-2)" "unprognostic (1.09e-3)" "potential prognostic unfavorable (6.21e-4)" "unprognostic (1.23e-2)" "unprognostic (7.85e-3)" "unprognostic (1.76e-1)" "unprognostic (2.82e-1)" "unprognostic (1.50e-1)" "unprognostic (4.02e-2)" "unprognostic (1.34e-1)" "unprognostic (3.34e-2)" SFI1 "KIAA0542, PISD, PPP1R139" ENSG00000198089 "SFI1 centrin binding protein" A8K8P3 22 31488688-31618588 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.5" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 164.0;Endometrial luminal cells: 288.9;Epididymal principal cells: 164.7;Retinal horizontal cells: 250.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 71: Cerebellum - Nervous system development" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 66: Non-specific - Mitochondria" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 11 "unprognostic (1.36e-3)" "unprognostic (2.61e-1)" "unprognostic (6.82e-2)" "unprognostic (6.53e-2)" "unprognostic (6.89e-2)" "unprognostic (1.82e-1)" "unprognostic (3.39e-1)" "unprognostic (2.37e-1)" "potential prognostic favorable (9.67e-4)" "unprognostic (2.98e-1)" "unprognostic (8.68e-2)" "unprognostic (1.24e-1)" "unprognostic (6.63e-3)" "unprognostic (3.03e-3)" "unprognostic (2.03e-1)" "unprognostic (8.83e-3)" "unprognostic (9.20e-2)" "unprognostic (2.76e-1)" "unprognostic (7.30e-3)" "unprognostic (3.83e-1)" "unprognostic (3.99e-3)" "unprognostic (1.64e-3)" "unprognostic (8.00e-3)" "unprognostic (2.07e-1)" "potential prognostic favorable (5.72e-6)" "unprognostic (7.80e-3)" "unprognostic (5.04e-2)" "unprognostic (3.00e-2)" "unprognostic (2.05e-1)" "unprognostic (6.05e-2)" "unprognostic (1.27e-1)" SFMBT1 "DKFZp434L243, RU1, SFMBT" ENSG00000163935 "Scm like with four mbt domains 1" Q9UHJ3 3 52903572-53046750 "Predicted intracellular proteins" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 42.6" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 208.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Spleen - B-cells (Spleen), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036152, HPA064564" Enhanced Nucleoplasm NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 21: Testis - Mixed function" "Cluster 25: Non-specific - Transcription" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 18 Nucleoplasm "HPA036152: , HPA064564: " "unprognostic (9.98e-2)" "unprognostic (1.78e-1)" "unprognostic (4.98e-2)" "unprognostic (2.20e-1)" "unprognostic (7.04e-2)" "unprognostic (2.83e-1)" "unprognostic (2.64e-1)" "potential prognostic favorable (9.69e-4)" "unprognostic (2.70e-2)" "unprognostic (6.44e-3)" "potential prognostic favorable (3.28e-4)" "unprognostic (3.23e-2)" "unprognostic (2.05e-1)" "unprognostic (2.42e-3)" "unprognostic (1.63e-1)" "unprognostic (2.90e-1)" "unprognostic (1.55e-1)" "unprognostic (1.65e-1)" "unprognostic (5.38e-2)" "unprognostic (7.54e-2)" "unprognostic (6.94e-2)" "unprognostic (1.11e-1)" "unprognostic (2.06e-1)" "unprognostic (1.50e-2)" "potential prognostic favorable (8.40e-4)" "unprognostic (2.41e-1)" "unprognostic (3.67e-1)" "unprognostic (2.94e-2)" "unprognostic (1.63e-1)" "unprognostic (7.97e-2)" "unprognostic (9.84e-2)" SFMBT2 KIAA1617 ENSG00000198879 "Scm like with four mbt domains 2" Q5VUG0 10 7158624-7411488 "Predicted intracellular proteins" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 997.8;Macrophages: 533.2;Microglia: 2869.7;Pituicytes/FSCs: 1480.0;Podocytes: 1000.7;Prostatic glandular cells: 564.2;Rod photoreceptor cells: 814.2" "Cell type enriched" "Detected in all" 5 "central nervous system macrophage: 3486.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 4.6" "Group enriched" "Detected in many" 4 "dendritic cells: 2.4;monocytes: 4.6" "Cancer enhanced" "Detected in many" "Myeloma: 17.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA035447, HPA035448, HPA070388" Uncertain Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 14 "Nucleoplasm, Nuclear speckles" "HPA035447: , HPA035448: , HPA070388: " "unprognostic (7.97e-2)" "unprognostic (7.95e-2)" "unprognostic (2.94e-2)" "unprognostic (2.07e-2)" "unprognostic (1.26e-1)" "unprognostic (9.06e-2)" "unprognostic (4.86e-2)" "potential prognostic favorable (2.60e-4)" "unprognostic (5.09e-3)" "unprognostic (2.76e-1)" "unprognostic (2.23e-3)" "unprognostic (7.16e-2)" "unprognostic (1.76e-1)" "unprognostic (2.62e-2)" "unprognostic (2.64e-1)" "unprognostic (8.49e-2)" "unprognostic (1.62e-1)" "unprognostic (3.61e-1)" "unprognostic (7.57e-2)" "unprognostic (1.91e-1)" "unprognostic (1.22e-1)" "unprognostic (9.78e-3)" "unprognostic (3.26e-1)" "unprognostic (1.07e-2)" "unprognostic (2.25e-1)" "unprognostic (6.03e-2)" "unprognostic (4.55e-2)" "unprognostic (8.21e-3)" SFN YWHAS ENSG00000175793 Stratifin P31947 1 26863149-26864456 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 2404.7;skin 1: 1183.0;vagina: 678.0" "Group enriched" "Detected in many" 7 "Basal keratinocytes: 6517.9;Esophageal apical cells: 8730.6;Esophageal basal cells: 4503.0;Esophageal suprabasal cells: 10490.6;Ocular epithelial cells: 3989.3;Suprabasal keratinocytes: 10595.6" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 3201.7;Head and Neck Squamous Cell Carcinoma (TCGA): 3646.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 17 "basophil: 5.9" "Lineage enriched" "Detected in single" 17 "granulocytes: 5.9" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 1337.8;head and neck cancer: 928.9" "Breast - Breast myoepithelial cells, Colon - Colon enterocytes, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 6.8" "CAB006268, HPA011105, CAB040552, HPA061603" Enhanced Supported "Nucleoplasm,Nucleoli rim,Cytosol,Mid piece" "Secreted in other tissues" "No annotated function" NA Yes 35000000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 288 Cytosol "Nucleoplasm, Nucleoli rim, Mid piece" "CAB006268: , CAB040552: , HPA011105: , HPA061603: " "unprognostic (7.12e-2)" "unprognostic (4.62e-2)" "unprognostic (2.55e-3)" "unprognostic (6.27e-2)" "unprognostic (1.99e-1)" "unprognostic (3.80e-1)" "unprognostic (5.77e-3)" "unprognostic (1.07e-1)" "unprognostic (2.42e-1)" "unprognostic (1.82e-2)" "potential prognostic unfavorable (8.44e-5)" "unprognostic (5.73e-3)" "unprognostic (3.03e-2)" "validated prognostic unfavorable (1.03e-5)" "validated prognostic unfavorable (1.28e-6)" "potential prognostic unfavorable (2.53e-4)" "unprognostic (1.09e-2)" "unprognostic (2.34e-2)" "unprognostic (7.73e-2)" "unprognostic (1.45e-1)" "unprognostic (9.69e-2)" "unprognostic (2.18e-3)" "unprognostic (3.09e-1)" "unprognostic (2.75e-1)" "unprognostic (6.31e-3)" "unprognostic (1.48e-1)" "unprognostic (1.05e-1)" "unprognostic (2.31e-2)" "unprognostic (4.10e-1)" "unprognostic (8.75e-2)" "unprognostic (3.19e-2)" SFPQ "PPP1R140, PSF" ENSG00000116560 "Splicing factor proline and glutamine rich" P23246 1 35176378-35193446 "Cancer-related genes, Disease related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, DNA damage, DNA recombination, DNA repair, Immunity, Innate immunity, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009886, HPA047513, HPA054689" Enhanced Enhanced Nucleoplasm NA NA 13000000 "Cluster 13: Non-specific - Mitochondria" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 20: Non-specific - Transcription regulation" 114 Nucleoplasm "CAB009886: , HPA047513: , HPA054689: " "unprognostic (3.25e-1)" "unprognostic (4.17e-1)" "potential prognostic unfavorable (4.84e-4)" "unprognostic (8.81e-3)" "potential prognostic favorable (5.32e-5)" "unprognostic (1.67e-1)" "unprognostic (1.76e-1)" "unprognostic (5.08e-3)" "unprognostic (9.56e-2)" "unprognostic (8.54e-3)" "potential prognostic favorable (7.49e-4)" "unprognostic (3.28e-2)" "unprognostic (1.51e-1)" "validated prognostic unfavorable (5.59e-10)" "validated prognostic unfavorable (2.95e-4)" "unprognostic (1.52e-3)" "unprognostic (2.60e-2)" "unprognostic (5.96e-2)" "unprognostic (6.42e-3)" "unprognostic (1.56e-1)" "unprognostic (8.24e-2)" "unprognostic (2.22e-1)" "unprognostic (3.83e-3)" "unprognostic (4.72e-3)" "unprognostic (8.16e-2)" "unprognostic (8.18e-2)" "unprognostic (3.02e-1)" "unprognostic (9.60e-2)" "unprognostic (8.15e-2)" "unprognostic (1.36e-1)" "unprognostic (1.16e-1)" SFR1 "bA373N18.1, C10orf78, FLJ41960, MEI5, MEIR5" ENSG00000156384 "SWI5 dependent homologous recombination repair protein 1" Q86XK3 10 104122058-104126385 "Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Early primary spermatocytes: 252.3" "Cell type enhanced" "Detected in many" "oligodendrocyte: 21.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039617 Uncertain Supported "Nucleoplasm,Nucleoli rim,Centrosome" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 3: Early primary spermatocytes - Early meiosis" 11 "Nucleoli rim" "Nucleoplasm, Centrosome" "HPA039617: " "unprognostic (1.49e-1)" "unprognostic (2.08e-1)" "unprognostic (1.50e-1)" "unprognostic (1.93e-1)" "unprognostic (1.35e-1)" "unprognostic (5.32e-2)" "unprognostic (1.98e-2)" "unprognostic (3.19e-2)" "unprognostic (2.99e-2)" "potential prognostic favorable (3.49e-7)" "unprognostic (2.62e-1)" "unprognostic (1.79e-1)" "potential prognostic unfavorable (3.12e-6)" "unprognostic (2.58e-2)" "unprognostic (1.34e-2)" "unprognostic (5.05e-3)" "unprognostic (2.14e-1)" "unprognostic (2.53e-1)" "unprognostic (2.95e-2)" "unprognostic (1.95e-3)" "potential prognostic unfavorable (5.88e-4)" "unprognostic (1.37e-1)" "validated prognostic favorable (4.69e-5)" "validated prognostic favorable (8.04e-4)" "unprognostic (1.35e-1)" "unprognostic (1.14e-2)" "unprognostic (4.82e-2)" "unprognostic (4.60e-3)" "unprognostic (1.59e-2)" SFRP1 "FRP, FRP-1, SARP2" ENSG00000104332 "Secreted frizzled related protein 1" Q8N474 8 41261962-41309473 "Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Differentiation, Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 649.5" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 654.4;Breast secretory cells: 1532.9;Choroid plexus epithelial cells: 460.1;Fibroblasts: 248.6;Lacrimal acinar cells: 1663.1;Leydig cells: 478.6;Retinal pigment epithelial cells: 225.9;Salivary acinar cells: 541.8;Salivary myoepithelial cells: 520.4" "Group enriched" "Detected in many" 6 "choroid plexus epithelial cell: 530.5;LAMP5-LHX6 and Chandelier: 153.9" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 65.3;Skin Cutaneous Melanoma (TCGA): 68.4" "Region enriched" "Detected in all" 19 "choroid plexus: 1106.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 243.9" "Adrenal gland - Fibroblasts, Heart muscle - Cardiomyocytes, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblasts_2, Pancreas - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Eccrine sweat gland cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB008116 Approved "Secreted in other tissues" "Developmental protein" NA No 43000000 "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 3 "CAB008116: " "unprognostic (2.05e-2)" "unprognostic (4.71e-3)" "unprognostic (2.33e-2)" "unprognostic (8.99e-2)" "unprognostic (8.98e-2)" "unprognostic (3.91e-2)" "unprognostic (7.00e-3)" "unprognostic (4.54e-2)" "potential prognostic favorable (1.79e-4)" "potential prognostic favorable (9.75e-5)" "unprognostic (1.10e-3)" "potential prognostic favorable (2.03e-4)" "potential prognostic unfavorable (3.13e-4)" "unprognostic (1.12e-1)" "potential prognostic favorable (1.69e-4)" "unprognostic (2.55e-2)" "unprognostic (3.07e-3)" "unprognostic (1.03e-2)" "unprognostic (1.31e-2)" "unprognostic (3.41e-3)" "unprognostic (1.23e-1)" "unprognostic (8.99e-2)" "unprognostic (1.92e-1)" "unprognostic (1.14e-1)" "unprognostic (2.56e-2)" "unprognostic (6.31e-3)" "unprognostic (1.48e-1)" "unprognostic (1.91e-1)" "unprognostic (5.20e-2)" SFRP2 "FRP-2, SARP1, SDF-5" ENSG00000145423 "Secreted frizzled related protein 2" Q96HF1 4 153780591-153789083 "Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 342.0;gallbladder: 298.7;urinary bladder: 287.2" "Cell type enriched" "Detected in many" 11 "Fibroblasts: 702.0" "Cell type enriched" "Detected in many" 5 "fibroblast: 67.1" "Cancer enhanced" "Detected in all" "Pancreatic Adenocarcinoma (TCGA): 568.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 25.0" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Colon - Fibroblasts, Lung - Fibroblasts_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA002652 Approved "Intermediate filaments" "Secreted in other tissues" "Developmental protein" NA NA 59000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 29: Forebrain - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 108: Fibroblasts - ECM organization" 4 "Intermediate filaments" "HPA002652: " "unprognostic (9.13e-3)" "unprognostic (3.12e-1)" "unprognostic (2.81e-1)" "unprognostic (2.99e-1)" "potential prognostic unfavorable (7.96e-4)" "unprognostic (6.48e-2)" "unprognostic (4.77e-2)" "unprognostic (1.77e-3)" "unprognostic (7.63e-3)" "unprognostic (1.12e-1)" "unprognostic (1.16e-2)" "unprognostic (9.90e-2)" "unprognostic (1.46e-3)" "unprognostic (2.08e-3)" "unprognostic (3.34e-1)" "unprognostic (1.34e-2)" "unprognostic (1.50e-1)" "unprognostic (2.50e-2)" "unprognostic (6.72e-2)" "unprognostic (1.05e-2)" "potential prognostic unfavorable (2.62e-5)" "unprognostic (2.58e-2)" "unprognostic (2.10e-1)" "unprognostic (6.10e-2)" "unprognostic (5.48e-2)" "unprognostic (1.21e-1)" "unprognostic (1.37e-1)" "unprognostic (6.60e-3)" "unprognostic (8.45e-2)" "unprognostic (1.52e-2)" "unprognostic (7.68e-2)" SFRP4 "FRP-4, frpHE, FRZB-2" ENSG00000106483 "Secreted frizzled related protein 4" Q6FHJ7 7 37905932-38025695 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 582.1;endometrium 1: 436.9" "Cell type enhanced" "Detected in many" "Adipocytes: 143.8;Cardiomyocytes: 193.8;Decidual stromal cells: 259.9;Endometrial stromal cells: 359.7;Fibroblasts: 349.4;Myonuclei: 86.7;Myosatellite cells: 84.3;Ovarian stromal cells: 152.4;Peritubular myoid cells: 185.7;Smooth muscle cells: 93.2" "Cell type enhanced" "Detected in many" "fibroblast: 102.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 8.9;Gastric cancer: 17.3" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Lung - Fibroblasts_2, Minor Salivary Gland - Fibroblasts, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 5 "spinal cord: 70.5" "HPA009712, HPA050585" Enhanced "Secreted in female reproductive system" "Developmental protein" NA NA 1100000 "Cluster 75: Ovary - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 108: Fibroblasts - ECM organization" 5 "HPA009712: , HPA050585: " "potential prognostic favorable (6.92e-4)" "unprognostic (4.74e-2)" "unprognostic (3.73e-1)" "unprognostic (4.73e-2)" "unprognostic (1.86e-3)" "unprognostic (5.74e-2)" "unprognostic (2.06e-1)" "unprognostic (1.66e-2)" "unprognostic (2.79e-2)" "unprognostic (1.70e-2)" "unprognostic (2.14e-2)" "unprognostic (6.33e-2)" "potential prognostic unfavorable (4.62e-4)" "unprognostic (1.21e-2)" "unprognostic (3.67e-2)" "unprognostic (1.43e-1)" "unprognostic (2.81e-1)" "unprognostic (2.00e-1)" "unprognostic (2.90e-1)" "unprognostic (4.99e-3)" "unprognostic (6.36e-3)" "unprognostic (1.91e-1)" "unprognostic (6.05e-3)" "unprognostic (1.06e-1)" "unprognostic (4.72e-2)" "unprognostic (2.99e-3)" "unprognostic (1.59e-1)" "unprognostic (2.27e-2)" "unprognostic (1.88e-1)" "unprognostic (5.30e-3)" "unprognostic (4.51e-2)" SFRP5 SARP3 ENSG00000120057 "Secreted frizzled related protein 5" Q5T4F7 10 97766751-97771999 "Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "choroid plexus: 215.9;heart muscle: 71.7;pancreas: 135.1" "Cell type enhanced" "Detected in some" "Cholangiocytes: 307.0;Epididymal basal cells: 52.4;Pancreatic duct cells: 353.3;Retinal pigment epithelial cells: 528.6;Schwann cells: 121.2" "Group enriched" "Detected in some" 4 "Bergmann glia: 6.4;choroid plexus epithelial cell: 19.1" "Cancer enhanced" "Detected in many" "Pancreatic Adenocarcinoma (TCGA): 41.4" "Region enriched" "Detected in all" 7 "choroid plexus: 203.7" "Immune cell enriched" "Detected in single" 4 "naive CD8 T-cell: 3.6" "Lineage enriched" "Detected in single" 4 "T-cells: 3.6" "Cancer enhanced" "Detected in some" "Gastric cancer: 4.6;prostate cancer: 8.8" "Adrenal gland - Adrenal medulla cells, Liver - Cholangiocytes, Lung - Alveolar cells type 2" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 8 "spinal cord: 159.2" "Secreted in other tissues" "Developmental protein" NA NA 3200000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 8: Pancreas - Proteolysis" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 18: Liver cancer - Metabolism" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" "unprognostic (5.71e-2)" "unprognostic (1.49e-1)" "unprognostic (7.13e-2)" "unprognostic (6.42e-3)" "unprognostic (5.18e-3)" "unprognostic (8.91e-2)" "unprognostic (1.08e-2)" "unprognostic (2.27e-1)" "unprognostic (2.08e-1)" "unprognostic (3.98e-1)" "unprognostic (1.73e-2)" "unprognostic (2.00e-1)" "unprognostic (3.98e-1)" SFSWAP "SFRS8, SWAP" ENSG00000061936 "Splicing factor SWAP" Q12872 12 131711081-131799738 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039362, HPA040063" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 38: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 14 Nucleoplasm "Plasma membrane, Cytosol" "HPA039362: , HPA040063: " "unprognostic (5.91e-2)" "unprognostic (1.35e-1)" "unprognostic (3.06e-1)" "unprognostic (2.32e-3)" "unprognostic (1.38e-2)" "unprognostic (5.54e-2)" "unprognostic (1.09e-3)" "unprognostic (7.37e-2)" "unprognostic (1.23e-1)" "potential prognostic unfavorable (8.76e-4)" "unprognostic (2.26e-1)" "unprognostic (2.79e-2)" "unprognostic (1.06e-2)" "unprognostic (1.45e-1)" "unprognostic (2.58e-2)" "unprognostic (9.19e-2)" "unprognostic (1.15e-1)" "unprognostic (6.75e-2)" "unprognostic (2.35e-1)" "unprognostic (1.64e-1)" "unprognostic (2.75e-2)" "unprognostic (7.91e-3)" "unprognostic (5.75e-3)" "unprognostic (1.85e-1)" "unprognostic (1.25e-2)" "potential prognostic unfavorable (6.46e-4)" "unprognostic (5.19e-2)" "unprognostic (5.43e-2)" "unprognostic (1.11e-1)" "unprognostic (1.13e-1)" SFT2D1 "C6orf83, MGC19825, pRGR1" ENSG00000198818 "SFT2 domain containing 1" Q8WV19 6 166319728-166342576 "Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 356.7;Gastric progenitor cells: 465.2;Neutrophils: 450.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014677 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 27 "Nuclear bodies" "Nucleoplasm, Cytosol" "HPA014677: " "unprognostic (1.73e-3)" "unprognostic (4.11e-3)" "unprognostic (5.51e-3)" "unprognostic (1.59e-2)" "unprognostic (4.99e-1)" "unprognostic (3.40e-2)" "unprognostic (4.12e-1)" "unprognostic (2.40e-1)" "unprognostic (2.57e-3)" "unprognostic (2.99e-2)" "unprognostic (1.73e-2)" "unprognostic (1.72e-1)" "unprognostic (4.69e-3)" "potential prognostic unfavorable (9.50e-7)" "unprognostic (1.14e-1)" "unprognostic (1.99e-2)" "unprognostic (8.46e-2)" "unprognostic (5.25e-3)" "unprognostic (2.69e-1)" "unprognostic (8.60e-2)" "unprognostic (3.05e-1)" "unprognostic (1.90e-3)" "unprognostic (3.43e-2)" "unprognostic (3.21e-1)" "unprognostic (3.25e-1)" "unprognostic (3.58e-1)" "unprognostic (1.06e-1)" "unprognostic (4.87e-2)" "unprognostic (1.19e-1)" "unprognostic (5.02e-2)" "unprognostic (1.20e-1)" SFT2D2 "dJ747L4.C1.2, UNQ512" ENSG00000213064 "SFT2 domain containing 2" O95562 1 168225938-168253021 "Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Corticotrophs: 246.1;Esophageal apical cells: 261.8;Kupffer cells: 192.7;Late spermatids: 260.1" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 104.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 53.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042207 Approved NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 24 "HPA042207: " "unprognostic (3.61e-2)" "unprognostic (2.51e-1)" "unprognostic (4.71e-2)" "unprognostic (6.77e-2)" "unprognostic (3.43e-1)" "unprognostic (1.87e-1)" "unprognostic (8.67e-2)" "unprognostic (2.33e-1)" "potential prognostic favorable (8.40e-4)" "unprognostic (2.22e-2)" "potential prognostic favorable (7.27e-5)" "unprognostic (2.13e-2)" "unprognostic (2.44e-1)" "potential prognostic unfavorable (6.53e-4)" "unprognostic (1.21e-1)" "unprognostic (8.34e-2)" "unprognostic (3.16e-3)" "unprognostic (2.37e-1)" "unprognostic (1.17e-1)" "unprognostic (4.57e-2)" "unprognostic (4.98e-3)" "unprognostic (1.02e-1)" "unprognostic (2.01e-1)" "unprognostic (2.38e-1)" "unprognostic (1.51e-2)" "unprognostic (1.06e-1)" "unprognostic (1.67e-1)" "unprognostic (1.92e-1)" "unprognostic (1.62e-1)" "unprognostic (3.59e-3)" "unprognostic (1.04e-1)" SFT2D3 MGC5391 ENSG00000173349 "SFT2 domain containing 3" Q587I9 2 127701497-127705242 "Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Retinal pigment epithelial cells: 34.1" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Prostate Adenocarcinoma (TCGA): 8.2;Uterine Corpus Endometrial Carcinoma (TCGA): 7.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" 11 "unprognostic (2.06e-2)" "unprognostic (7.52e-2)" "unprognostic (3.62e-2)" "unprognostic (3.48e-1)" "unprognostic (3.79e-2)" "unprognostic (1.06e-1)" "unprognostic (5.39e-2)" SFTA2 "SFTPG, SP-G" ENSG00000196260 "Surfactant associated 2" Q6UW10 6 30931353-30955636 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 48.9;lung: 178.9" "Group enriched" "Detected in some" 12 "Alveolar cells type 1: 413.3;Alveolar cells type 2: 860.8;Esophageal apical cells: 808.8;Transitional alveolar cells: 477.4" "Cell type enhanced" "Detected in single" "ependymal cell: 2.0" "Cancer enriched" "Detected in many" 12 "Lung Adenocarcinoma (TCGA): 213.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 4.1;breast cancer: 3.0;lung cancer: 2.5" "Lung - Alveolar cells type 2" "Not detected" "Not detected" "Secreted in other tissues" "No annotated function" NA NA "Cluster 13: Lung - Secretion" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 81: Alveolar cells - Lung function" "unprognostic (1.86e-1)" "unprognostic (6.37e-1)" "unprognostic (4.82e-2)" "unprognostic (5.32e-2)" "unprognostic (1.77e-1)" "unprognostic (1.92e-3)" "unprognostic (6.34e-2)" "unprognostic (4.86e-1)" "unprognostic (8.90e-2)" "unprognostic (4.73e-2)" "unprognostic (5.73e-2)" "unprognostic (5.04e-2)" "unprognostic (7.82e-2)" "unprognostic (3.60e-3)" "unprognostic (2.51e-2)" "unprognostic (2.03e-1)" "unprognostic (2.38e-1)" "unprognostic (3.64e-2)" "unprognostic (9.61e-2)" SFTPA1 "COLEC4, SFTP1, SP-A, SP-A1" ENSG00000122852 "Surfactant protein A1" Q8IWL2 10 79610939-79615455 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Gaseous exchange" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 1048 "lung: 6679.7" "Cell type enriched" "Detected in some" 7 "Alveolar cells type 2: 15062.8" "Not detected" "Not detected" "Group enriched" "Detected in some" 27 "Lung Adenocarcinoma (TCGA): 1891.3;Lung Squamous Cell Carcinoma (TCGA): 520.0" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 27 "plasmacytoid DC: 2.7" "Lineage enriched" "Detected in single" 27 "dendritic cells: 2.7" "Cancer enriched" "Detected in single" 7 "lung cancer: 6.4" "Lung - Alveolar cells type 2" "CAB016793, HPA042638, HPA045752, HPA049368" Supported "Secreted in other tissues" Other NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 13: Lung - Secretion" "Cluster 37: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 81: Alveolar cells - Lung function" 3 "CAB016793: , HPA042638: , HPA045752: , HPA049368: " "unprognostic (1.48e-2)" "unprognostic (1.45e-1)" "unprognostic (9.35e-3)" "unprognostic (2.55e-1)" "unprognostic (3.32e-1)" "unprognostic (1.32e-1)" SFTPA2 "COLEC5, SP-A2" ENSG00000185303 "Surfactant protein A2" Q8IWL1 10 79555852-79560407 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Gaseous exchange" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 406 "lung: 10182.2" "Cell type enriched" "Detected in some" 5 "Alveolar cells type 2: 19329.6" "Not detected" "Not detected" "Group enriched" "Detected in many" 22 "Lung Adenocarcinoma (TCGA): 2684.8;Lung Squamous Cell Carcinoma (TCGA): 772.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "lung cancer: 6.8;prostate cancer: 6.9" "Lung - Alveolar cells type 2, Prostate - Prostate glandular cells" "CAB002439, HPA042638, HPA045752, HPA049368" Enhanced "Secreted in other tissues" Other NA NA "Cluster 13: Lung - Secretion" "Cluster 37: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 81: Alveolar cells - Lung function" 19 "CAB002439: , HPA042638: , HPA045752: , HPA049368: " "unprognostic (3.40e-2)" "unprognostic (8.46e-2)" "unprognostic (4.41e-1)" "unprognostic (4.82e-3)" "unprognostic (1.14e-2)" "unprognostic (1.60e-2)" "unprognostic (1.45e-1)" "unprognostic (6.37e-3)" "unprognostic (2.09e-1)" "potential prognostic unfavorable (4.38e-4)" "unprognostic (1.82e-1)" "unprognostic (2.24e-1)" "unprognostic (1.34e-1)" "unprognostic (2.13e-1)" "unprognostic (1.89e-1)" "unprognostic (1.25e-1)" SFTPB "SFTP3, SP-B" ENSG00000168878 "Surfactant protein B" P07988 2 85657314-85668741 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Gaseous exchange" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 30 "lung: 3361.2" "Group enriched" "Detected in some" 22 "Alveolar cells type 1: 9996.4;Alveolar cells type 2: 19160.6;Transitional alveolar cells: 14487.9" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "Lung Adenocarcinoma (TCGA): 4657.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in some" "thyroid cancer: 19.2" "Lung - Alveolar cells type 2" "Not detected" "Not detected" "Not detected" "Not detected" "CAB002440, HPA034820, HPA062148" Enhanced "Secreted in other tissues" Other NA NA 12000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 13: Lung - Secretion" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 81: Alveolar cells - Lung function" "CAB002440: , HPA034820: , HPA062148: " "unprognostic (3.93e-3)" "unprognostic (5.92e-2)" "unprognostic (1.06e-3)" "unprognostic (8.42e-2)" "unprognostic (1.81e-1)" "potential prognostic unfavorable (6.27e-5)" "unprognostic (2.12e-1)" "potential prognostic favorable (2.31e-4)" "unprognostic (7.63e-3)" "unprognostic (1.43e-2)" "unprognostic (1.23e-1)" "unprognostic (3.92e-3)" "unprognostic (1.94e-2)" "unprognostic (2.97e-2)" "unprognostic (4.81e-2)" "unprognostic (1.33e-2)" "unprognostic (6.38e-2)" "unprognostic (6.88e-2)" "unprognostic (2.34e-2)" SFTPC "BRICD6, PSP-C, SFTP2, SMDP2, SP-C" ENSG00000168484 "Surfactant protein C" P11686 8 22156913-22164479 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Gaseous exchange" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 794 "lung: 17411.2" "Cell type enriched" "Detected in some" 6 "Alveolar cells type 2: 101266.2" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 12.3;oligodendrocyte: 18.7" "Group enriched" "Detected in many" 279 "Lung Adenocarcinoma (TCGA): 2101.0;Lung Squamous Cell Carcinoma (TCGA): 677.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Sarcoma: 1.5;skin cancer: 1.3" "Lung - Alveolar cells type 2, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA010928 Enhanced "Secreted in other tissues" Other NA NA "Cluster 13: Lung - Secretion" "Cluster 11: White matter - Signal transduction" "Cluster 34: Testis cancer - Unknown function" "Cluster 81: Alveolar cells - Lung function" 138 "HPA010928: " "unprognostic (9.11e-1)" "unprognostic (2.90e-1)" "unprognostic (4.36e-3)" "unprognostic (9.19e-2)" "unprognostic (3.62e-2)" "unprognostic (3.10e-1)" "unprognostic (4.25e-1)" "unprognostic (5.93e-2)" SFTPD "COLEC7, SFTP4, SP-D" ENSG00000133661 "Surfactant protein D" P35247 10 79937467-79982614 "Predicted secreted proteins" "Gaseous exchange, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 26 "lung: 479.1" "Group enriched" "Detected in many" 4 "Alveolar cells type 2: 1441.8;Transitional alveolar cells: 367.3" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 37.7" "Group enriched" "Detected in many" 15 "Lung Adenocarcinoma (TCGA): 258.5;Lung Squamous Cell Carcinoma (TCGA): 70.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "intermediate monocyte: 10.0;non-classical monocyte: 36.5" "Lineage enriched" "Detected in many" 18 "monocytes: 36.5" "Low cancer specificity" "Detected in some" "Adrenal gland - Adrenal medulla cells, Lung - Alveolar cells type 2, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB004578, HPA044582, HPA056768" Enhanced "Secreted in other tissues" Immunity NA NA 1200000 "Cluster 40: Monocytes - Innate immune response" "Cluster 13: Lung - Secretion" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 1: Neuronal - Visual perception" "Cluster 81: Alveolar cells - Lung function" 2 "CAB004578: , HPA044582: , HPA056768: " "unprognostic (3.65e-2)" "unprognostic (8.24e-3)" "unprognostic (1.04e-1)" "unprognostic (1.41e-2)" "unprognostic (8.85e-2)" "unprognostic (5.51e-2)" "potential prognostic favorable (7.92e-5)" "potential prognostic favorable (1.26e-4)" "unprognostic (1.67e-2)" "potential prognostic favorable (9.46e-6)" "unprognostic (1.48e-3)" "unprognostic (4.69e-2)" "unprognostic (3.29e-2)" "unprognostic (2.59e-1)" "unprognostic (1.57e-1)" "unprognostic (3.95e-1)" "unprognostic (1.41e-1)" "unprognostic (2.92e-1)" "unprognostic (1.40e-1)" "unprognostic (4.79e-3)" "unprognostic (2.00e-1)" "unprognostic (1.82e-1)" "unprognostic (2.17e-2)" SFXN1 "FLJ12876, SLC56A1" ENSG00000164466 "Sideroflexin 1" Q9H9B4 5 175477062-175529742 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, One-carbon metabolism, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 93.1" "Cell type enhanced" "Detected in many" "Neutrophil progenitors: 246.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 99.5" "Group enriched" "Detected in all" 5 "granulocytes: 99.5;T-cells: 36.4" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019543, HPA063745" Approved Enhanced Mitochondria NA NA 34000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 121 Mitochondria "HPA019543: , HPA063745: " "unprognostic (6.03e-2)" "unprognostic (1.13e-3)" "unprognostic (9.74e-3)" "unprognostic (4.26e-3)" "unprognostic (8.88e-3)" "unprognostic (3.13e-1)" "unprognostic (8.05e-2)" "unprognostic (3.26e-1)" "potential prognostic unfavorable (5.35e-4)" "potential prognostic unfavorable (6.12e-4)" "potential prognostic favorable (1.27e-7)" "unprognostic (6.61e-3)" "unprognostic (2.87e-2)" "unprognostic (5.55e-2)" "unprognostic (7.49e-2)" "potential prognostic unfavorable (5.60e-4)" "unprognostic (1.55e-2)" "unprognostic (3.44e-1)" "unprognostic (2.88e-3)" "unprognostic (2.86e-1)" "unprognostic (6.90e-3)" "unprognostic (1.40e-1)" "unprognostic (1.55e-2)" "unprognostic (3.60e-2)" "unprognostic (9.19e-2)" "unprognostic (1.57e-1)" "unprognostic (2.53e-2)" "unprognostic (1.94e-1)" "unprognostic (2.77e-1)" "unprognostic (1.99e-3)" "unprognostic (2.79e-1)" SFXN2 SLC56A2 ENSG00000156398 "Sideroflexin 2" Q96NB2 10 102714538-102743492 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 16.7;parathyroid gland: 11.9" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 56.8;Ovarian stromal cells: 49.3;Proximal tubule cells: 86.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA018150, HPA026834" Enhanced Approved Mitochondria NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 72: Kidney - Transmembrane transport" "Cluster 48: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 94: Gonadal somatic cells - Mixed function" 39 Mitochondria "HPA018150: , HPA026834: " "unprognostic (3.69e-2)" "unprognostic (7.33e-2)" "unprognostic (6.06e-2)" "unprognostic (4.45e-1)" "unprognostic (3.14e-2)" "unprognostic (2.76e-1)" "unprognostic (3.51e-1)" "unprognostic (2.13e-3)" "unprognostic (3.22e-3)" "unprognostic (3.69e-1)" "potential prognostic favorable (5.04e-5)" "unprognostic (3.82e-2)" "unprognostic (1.03e-1)" "unprognostic (9.19e-3)" "unprognostic (1.64e-1)" "unprognostic (1.91e-2)" "unprognostic (1.98e-1)" "unprognostic (2.90e-1)" "unprognostic (1.10e-1)" "unprognostic (8.61e-2)" "unprognostic (1.60e-1)" "unprognostic (1.23e-1)" "unprognostic (1.77e-1)" "unprognostic (1.11e-1)" "potential prognostic favorable (1.61e-4)" "unprognostic (6.71e-2)" "unprognostic (1.13e-1)" "unprognostic (2.58e-1)" "unprognostic (1.88e-1)" "unprognostic (6.80e-2)" "unprognostic (1.67e-1)" SFXN3 "SFX3, SLC56A3" ENSG00000107819 "Sideroflexin 3" Q9BWM7 10 101031234-101041241 "Metabolic proteins, Predicted membrane proteins" "Amino-acid transport, One-carbon metabolism, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 60.2;Enterocytes: 119.9;Extravillous trophoblasts: 63.7;Late spermatids: 275.1;Respiratory ciliated cells: 56.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008028, HPA048105" Approved Enhanced Mitochondria NA NA 5300 "Cluster 42: Non-specific - Vesicular transport" "Cluster 77: Intestine - Digestion" "Cluster 34: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 1: Enterocytes - Absorption and Digestion" 49 Mitochondria "HPA008028: , HPA048105: " "unprognostic (1.71e-1)" "unprognostic (9.85e-3)" "unprognostic (3.92e-1)" "unprognostic (1.02e-2)" "unprognostic (3.37e-3)" "unprognostic (4.15e-2)" "unprognostic (5.63e-2)" "unprognostic (2.44e-1)" "potential prognostic unfavorable (5.34e-4)" "unprognostic (2.73e-1)" "potential prognostic favorable (3.67e-5)" "unprognostic (2.44e-1)" "unprognostic (4.81e-1)" "potential prognostic unfavorable (6.24e-4)" "unprognostic (3.62e-1)" "unprognostic (6.97e-2)" "unprognostic (4.97e-3)" "unprognostic (1.46e-2)" "unprognostic (8.06e-2)" "potential prognostic unfavorable (6.22e-4)" "unprognostic (4.27e-3)" "unprognostic (1.70e-3)" "unprognostic (1.57e-2)" "unprognostic (1.09e-1)" "unprognostic (3.31e-1)" "unprognostic (1.68e-2)" "unprognostic (1.58e-1)" "unprognostic (4.11e-1)" "unprognostic (5.34e-2)" "unprognostic (1.57e-1)" "unprognostic (5.37e-2)" SFXN4 SLC56A4 ENSG00000183605 "Sideroflexin 4" Q6P4A7 10 119140767-119165714 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 128.4;Myonuclei: 193.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018028, HPA020872" Approved Approved Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 55: Myocytes - Oxidative muscle function" 33 "Nucleoplasm, Mitochondria" Vesicles "HPA018028: , HPA020872: " "unprognostic (2.97e-2)" "unprognostic (2.48e-2)" "unprognostic (9.87e-2)" "unprognostic (2.41e-1)" "unprognostic (3.62e-1)" "unprognostic (1.58e-1)" "unprognostic (6.40e-2)" "unprognostic (7.00e-3)" "unprognostic (4.88e-2)" "potential prognostic unfavorable (8.90e-4)" "potential prognostic favorable (9.38e-8)" "unprognostic (6.62e-2)" "unprognostic (6.83e-2)" "unprognostic (2.13e-2)" "unprognostic (1.67e-1)" "unprognostic (4.68e-2)" "unprognostic (1.48e-2)" "unprognostic (1.20e-1)" "unprognostic (1.40e-1)" "unprognostic (9.25e-2)" "unprognostic (3.01e-3)" "unprognostic (3.63e-2)" "unprognostic (1.09e-1)" "unprognostic (1.93e-2)" "unprognostic (5.47e-3)" "unprognostic (9.23e-3)" "unprognostic (4.54e-2)" "unprognostic (1.81e-2)" "unprognostic (3.11e-1)" "unprognostic (2.15e-3)" "unprognostic (2.19e-1)" SFXN5 "BBG-TCC, SLC56A5" ENSG00000144040 "Sideroflexin 5" Q8TD22 2 72942036-73075619 "Predicted intracellular proteins, Predicted membrane proteins" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 74.7;liver: 37.1" "Cell type enhanced" "Detected in many" "Astrocytes: 713.1;Bergmann glia: 824.4;Distal convoluted tubule cells: 179.3;Ependymal cells: 194.3;Late spermatids: 245.9" "Group enriched" "Detected in all" 5 "astrocyte: 714.4;Bergmann glia: 887.5;ependymal cell: 225.6" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 48.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015473, HPA056866" Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 78: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 72: Neuronal - Signal transduction" "Cluster 28: Astrocytes - Homeostasis & neuron support" 14 "Nucleoplasm, Mitochondria" "HPA015473: , HPA056866: " "unprognostic (1.15e-2)" "unprognostic (9.98e-2)" "unprognostic (7.87e-2)" "unprognostic (9.74e-3)" "unprognostic (2.85e-1)" "unprognostic (2.53e-2)" "unprognostic (2.20e-1)" "unprognostic (2.02e-1)" "unprognostic (1.38e-2)" "unprognostic (5.17e-1)" "unprognostic (2.43e-1)" "unprognostic (7.43e-2)" "unprognostic (9.50e-2)" "unprognostic (3.19e-1)" "unprognostic (3.10e-2)" "unprognostic (1.60e-3)" "unprognostic (1.05e-1)" "unprognostic (4.61e-2)" "unprognostic (1.45e-1)" "unprognostic (8.46e-2)" "unprognostic (1.14e-1)" "potential prognostic favorable (8.55e-4)" "potential prognostic unfavorable (4.53e-4)" "unprognostic (1.16e-1)" "unprognostic (1.16e-1)" "unprognostic (3.70e-2)" "unprognostic (1.15e-2)" "unprognostic (1.51e-1)" "unprognostic (6.82e-2)" "unprognostic (3.65e-2)" "unprognostic (1.64e-3)" SGCA "A2, adhalin, ADL, DMDA2, LGMD2D, SCARMD1" ENSG00000108823 "Sarcoglycan alpha" Q16586 17 50164214-50175928 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "blood vessel: 168.4;heart muscle: 118.7;skeletal muscle: 435.8;tongue: 202.7" "Cell type enriched" "Detected in some" 6 "Late spermatids: 1094.4" "Group enriched" "Detected in some" 5 "fibroblast: 13.5;pericyte: 7.7;vascular associated smooth muscle cell: 29.5" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 12.1" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "intermediate monocyte: 1.0;memory B-cell: 2.9;myeloid DC: 1.5;naive B-cell: 2.8;non-classical monocyte: 1.4" "Group enriched" "Detected in many" 20 "B-cells: 2.9;dendritic cells: 1.5;monocytes: 1.4" "Cancer enriched" "Detected in single" 35 "Sarcoma: 23.1" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Adrenal gland - Smooth muscle cells, Heart muscle - Cardiomyocytes, Liver - Hepatic stellate cells, Prostate - Smooth muscle cells, Spleen - Smooth muscle cells, Stomach - Fibroblasts, Testis - Late spermatids, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA007537 Uncertain "Intracellular and membrane" "No annotated function" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 70 "HPA007537: " "unprognostic (1.03e-1)" "unprognostic (1.72e-1)" "unprognostic (5.54e-2)" "unprognostic (1.71e-2)" "unprognostic (5.63e-2)" "unprognostic (2.71e-2)" "unprognostic (4.67e-3)" "unprognostic (6.55e-3)" "unprognostic (8.90e-2)" "unprognostic (2.98e-3)" "unprognostic (3.62e-3)" "unprognostic (1.22e-1)" "potential prognostic unfavorable (6.21e-5)" "unprognostic (3.32e-2)" "unprognostic (1.43e-1)" "potential prognostic favorable (1.32e-5)" "unprognostic (1.32e-1)" "unprognostic (6.24e-3)" "unprognostic (3.96e-2)" "unprognostic (6.44e-2)" "unprognostic (2.42e-1)" "unprognostic (2.02e-1)" SGCB "A3b, LGMD2E, SGC" ENSG00000163069 "Sarcoglycan beta" Q16585 4 52020706-52038299 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 98.9" "Cell type enhanced" "Detected in many" "Late spermatids: 300.1;Schwann cells: 122.1;Thymic myoid cells: 159.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 100.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Endothelial cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011422, HPA058656" Enhanced Approved Cytosol NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 32 Cytosol "HPA011422: , HPA058656: " "unprognostic (1.63e-1)" "unprognostic (3.94e-2)" "unprognostic (1.05e-1)" "unprognostic (1.39e-1)" "unprognostic (5.38e-2)" "unprognostic (1.76e-1)" "unprognostic (3.16e-1)" "unprognostic (3.96e-2)" "unprognostic (2.00e-2)" "unprognostic (2.70e-1)" "validated prognostic favorable (2.23e-11)" "validated prognostic favorable (4.38e-4)" "unprognostic (1.76e-3)" "unprognostic (1.48e-3)" "unprognostic (2.28e-2)" "unprognostic (3.50e-2)" "unprognostic (2.20e-2)" "unprognostic (8.81e-3)" "unprognostic (2.83e-1)" "unprognostic (1.98e-1)" "unprognostic (2.77e-3)" "unprognostic (6.67e-2)" "unprognostic (1.76e-1)" "unprognostic (1.51e-1)" "unprognostic (2.37e-1)" "unprognostic (5.63e-2)" "unprognostic (1.06e-1)" "unprognostic (2.58e-2)" "unprognostic (5.69e-2)" "unprognostic (1.20e-1)" "unprognostic (1.77e-1)" SGCD "CMD1L, DAGD, LGMD2F" ENSG00000170624 "Sarcoglycan delta" Q92629 5 155870344-156767788 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cardiomyopathy, Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 36.6;skeletal muscle: 40.2;tongue: 31.1" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 776.5;Astrocytes: 698.8;Cardiomyocytes: 2865.4;Cone photoreceptor cells: 892.2;Melanocytes: 722.7;Myonuclei: 2979.1;Oligodendrocyte progenitor cells: 1010.3;Retinal horizontal cells: 951.6;Somatotrophs: 1052.1;Thymic myoid cells: 776.3" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 4 "Skin Cutaneous Melanoma (TCGA): 20.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 11.2" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Cardiomyocytes, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Minor Salivary Gland - Fibroblasts, Pancreas - Fibroblasts, Pituitary gland - Somatotropes, Prostate - Fibroblasts, Spleen - Fibroblasts_1, Spleen - Fibroblasts_2, Stomach - Fibroblasts, Testis - Peritubular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 41: Striated muscle - Muscle contraction" "Cluster 27: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 55: Myocytes - Oxidative muscle function" 3 "unprognostic (6.41e-3)" "unprognostic (2.24e-1)" "unprognostic (2.89e-1)" "unprognostic (2.78e-2)" "unprognostic (1.61e-1)" "unprognostic (1.34e-1)" "potential prognostic favorable (5.68e-4)" "unprognostic (5.72e-2)" "unprognostic (5.90e-2)" "unprognostic (3.96e-2)" "unprognostic (3.00e-1)" "unprognostic (3.19e-2)" "unprognostic (1.42e-1)" "unprognostic (6.03e-2)" "unprognostic (1.35e-1)" "unprognostic (2.36e-3)" "unprognostic (1.89e-1)" "unprognostic (3.64e-2)" "unprognostic (1.05e-1)" "unprognostic (2.73e-1)" "unprognostic (2.89e-2)" "unprognostic (2.62e-2)" "unprognostic (6.45e-3)" "unprognostic (2.98e-2)" "unprognostic (3.24e-3)" "unprognostic (3.86e-2)" SGCE DYT11 ENSG00000127990 "Sarcoglycan epsilon" O43556 7 94524204-94656572 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Dystonia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 115.3" "Cell type enhanced" "Detected in many" "Corticotrophs: 263.4;Gonadotrophs: 327.0;Lactotrophs: 318.4;Sertoli cells: 283.6;Thyrotrophs: 362.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "gdT-cell: 2.1;memory B-cell: 4.5;naive B-cell: 6.7" "Group enriched" "Detected in many" 4 "B-cells: 6.7;T-cells: 2.1" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells, Liver - Hepatic stellate cells, Prostate - Smooth muscle cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074790 Approved "Nucleoplasm,Golgi apparatus,Vesicles,Plasma membrane" Yes No 120000 "Cluster 34: B-cells - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 30: White matter - Myelination" "Cluster 15: Kidney cancer - Membrane components" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" "Vesicles, Plasma membrane" "Nucleoplasm, Golgi apparatus" "HPA074790: " "unprognostic (3.28e-2)" "unprognostic (2.66e-3)" "unprognostic (1.55e-1)" "unprognostic (4.71e-2)" "unprognostic (9.55e-3)" "unprognostic (2.64e-1)" "unprognostic (7.49e-2)" "unprognostic (1.60e-1)" "potential prognostic unfavorable (4.74e-4)" "unprognostic (4.71e-2)" "potential prognostic favorable (1.56e-4)" "unprognostic (1.33e-1)" "unprognostic (1.45e-1)" "unprognostic (1.27e-2)" "potential prognostic unfavorable (5.49e-4)" "unprognostic (2.06e-1)" "unprognostic (4.04e-3)" "unprognostic (7.89e-3)" "unprognostic (1.07e-1)" "unprognostic (1.49e-2)" "unprognostic (1.60e-1)" "unprognostic (8.77e-3)" "unprognostic (6.87e-3)" "unprognostic (1.54e-1)" "unprognostic (8.73e-2)" "unprognostic (3.65e-2)" "unprognostic (3.95e-1)" "potential prognostic unfavorable (8.74e-4)" "unprognostic (1.62e-1)" "unprognostic (1.01e-1)" "unprognostic (3.08e-1)" SGCG "A4, DAGA4, DMDA, DMDA1, LGMD2C, MAM, MGC130048, SCARMD2, SCG3, TYPE" ENSG00000102683 "Sarcoglycan gamma" Q13326 13 23180979-23325162 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "heart muscle: 111.2;skeletal muscle: 148.0;tongue: 134.5" "Cell type enhanced" "Detected in some" "Adipocytes: 179.4;Cardiomyocytes: 423.7;Myonuclei: 946.8;Thymic myoid cells: 477.2" "Cell type enhanced" "Detected in many" "hippocampal dentate gyrus: 28.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 6.7" "Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Lung - Fibroblasts_1, Prostate - Fibroblasts, Skeletal muscle - Skeletal myocytes, Stomach - Fibroblasts, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA007476 Enhanced NA NA "Cluster 41: Striated muscle - Muscle contraction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 14 "HPA007476: " "unprognostic (4.71e-2)" "unprognostic (1.44e-1)" "unprognostic (2.76e-2)" "unprognostic (6.11e-2)" "unprognostic (1.51e-1)" "unprognostic (2.34e-1)" SGCZ ZSG1 ENSG00000185053 "Sarcoglycan zeta" Q96LD1 8 14084845-15238431 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "ovary: 1.2" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 895.3;Brain inhibitory neurons: 1645.0;Corticotrophs: 1756.1;Medullary thymic epithelial cells: 1324.9;Oligodendrocyte progenitor cells: 1506.7;Other brain neurons: 1172.3;Retinal ganglion cells: 776.4;Somatotrophs: 752.5;Thyrotrophs: 379.0" "Cell type enhanced" "Detected in all" "LAMP5-LHX6 and Chandelier: 3789.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Rhabdoid: 1.3" "Prostate - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA017585 Uncertain NA NA "Cluster 65: Brain - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 109: Neurons - Neuronal signaling" 1 "HPA017585: " "unprognostic (2.91e-2)" SGF29 "CCDC101, FLJ32446, TDRD29" ENSG00000176476 "SAGA complex associated factor 29" Q96ES7 16 28553915-28591790 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Early spermatids: 270.5;Late spermatids: 524.4;Oocytes: 359.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052590, HPA053608" Enhanced Supported Nucleoplasm,Nucleoli Yes No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 24: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 54: Non-specific - Transcription" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 154 Nucleoli Nucleoplasm "HPA052590: , HPA053608: " "unprognostic (2.41e-2)" "unprognostic (9.86e-2)" "potential prognostic favorable (3.62e-4)" "unprognostic (9.87e-2)" "unprognostic (4.05e-2)" "unprognostic (1.90e-2)" "potential prognostic favorable (1.02e-4)" "unprognostic (1.10e-1)" "unprognostic (2.47e-1)" "potential prognostic favorable (2.45e-4)" "unprognostic (2.77e-2)" "unprognostic (6.61e-2)" "unprognostic (2.69e-2)" "unprognostic (3.70e-3)" "unprognostic (9.76e-2)" "unprognostic (5.41e-2)" "unprognostic (4.00e-2)" "unprognostic (4.73e-2)" "unprognostic (8.02e-2)" "potential prognostic favorable (3.49e-4)" "unprognostic (3.73e-1)" "unprognostic (4.38e-1)" "unprognostic (9.61e-2)" "unprognostic (3.74e-2)" "unprognostic (7.23e-2)" "unprognostic (8.07e-2)" "unprognostic (4.63e-1)" "unprognostic (2.11e-1)" "unprognostic (1.15e-1)" SGIP1 DKFZp761D221 ENSG00000118473 "SH3GL interacting endocytic adaptor 1" Q9BQI5 1 66533267-66751139 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "retina: 152.0" "Cell type enhanced" "Detected in many" "Astrocytes: 498.7;Bergmann glia: 581.5;Brain excitatory neurons: 394.3;Brain inhibitory neurons: 595.4;Cone photoreceptor cells: 1188.2;Ependymal cells: 637.2;Gonadotrophs: 454.3;Oligodendrocyte progenitor cells: 618.5;Other brain neurons: 395.7;Pericytes: 497.3;Podocytes: 819.5;Rod photoreceptor cells: 1607.9;Sertoli cells: 646.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 7.0" "Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017963 Approved Approved Mitochondria NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 79: Photoreceptor cells - Phototransduction" 19 Mitochondria "HPA017963: " "unprognostic (1.15e-1)" "unprognostic (1.55e-2)" "unprognostic (4.41e-2)" "unprognostic (2.39e-1)" "unprognostic (2.80e-1)" "potential prognostic favorable (3.02e-5)" "unprognostic (2.05e-1)" "unprognostic (2.54e-1)" "unprognostic (1.26e-1)" "unprognostic (2.48e-3)" "unprognostic (2.00e-2)" "unprognostic (8.59e-3)" "unprognostic (1.34e-2)" "unprognostic (3.49e-1)" "unprognostic (5.66e-2)" "unprognostic (6.87e-2)" "unprognostic (3.37e-1)" "unprognostic (1.20e-1)" "unprognostic (1.46e-1)" "unprognostic (3.06e-1)" "unprognostic (3.35e-2)" "unprognostic (3.38e-3)" "unprognostic (2.22e-2)" "unprognostic (4.24e-3)" SGK1 SGK ENSG00000118515 "Serum/glucocorticoid regulated kinase 1" O00141 6 134169248-134318112 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Apoptosis, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 946.1" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 538.2;cDC: 698.7;Choroid plexus epithelial cells: 1174.3;Endometrial glandular cells: 683.4;Enterocytes: 920.3;Mast cells: 617.1;Oligodendrocyte progenitor cells: 515.9;Oligodendrocytes: 763.2;Syncytiotrophoblasts: 732.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 43.5;eosinophil: 170.2;neutrophil: 91.8" "Group enriched" "Detected in all" 8 "granulocytes: 170.2;monocytes: 43.5" "Cancer enhanced" "Detected in all" "skin cancer: 215.3" "Kidney - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022085, CAB025148, HPA051251" Approved Enhanced "Nuclear speckles" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 82: Dendritic cells - Antigen presentation" 23 "Nuclear speckles" "CAB022085: , CAB025148: , HPA051251: " "unprognostic (3.04e-1)" "unprognostic (1.32e-1)" "unprognostic (9.93e-3)" "unprognostic (1.62e-2)" "unprognostic (2.10e-2)" "unprognostic (6.99e-2)" "unprognostic (7.46e-2)" "unprognostic (5.30e-2)" "unprognostic (9.50e-2)" "unprognostic (1.10e-2)" "potential prognostic favorable (1.38e-11)" "unprognostic (6.82e-3)" "unprognostic (5.73e-2)" "unprognostic (5.86e-2)" "unprognostic (6.69e-2)" "unprognostic (2.08e-1)" "unprognostic (4.63e-2)" "unprognostic (7.96e-3)" "unprognostic (7.45e-2)" "unprognostic (1.76e-2)" "unprognostic (2.80e-2)" "unprognostic (4.12e-2)" "potential prognostic unfavorable (2.52e-4)" "unprognostic (1.66e-1)" "unprognostic (3.50e-1)" "unprognostic (1.58e-2)" "unprognostic (4.41e-1)" "unprognostic (1.93e-2)" "unprognostic (1.04e-1)" "unprognostic (1.82e-1)" "unprognostic (1.25e-1)" SGK2 ENSG00000101049 "Serum/glucocorticoid regulated kinase 2" Q9HBY8 20 43558968-43588237 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 76.6;liver: 63.5" "Cell type enhanced" "Detected in many" "Adipocytes: 40.1;Colonocytes: 100.2;Distal convoluted tubule cells: 84.7;Enterocytes: 36.9;Epididymal clear cells: 30.6;Epididymal principal cells: 31.0;Hepatocytes: 47.1;Loop of henle epithelial cells: 66.0;Oligodendrocytes: 34.2;Proximal tubule cells: 45.3;Renal collecting duct intercalated cells: 77.7;Renal collecting duct principal cells: 37.3;Renal connecting tubule cells: 72.2" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 25.3;oligodendrocyte: 42.3" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 56.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 30.0" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Skin - Sebaceous gland cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008859, HPA011387" Uncertain Supported Nucleoplasm NA NA "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 30: White matter - Myelination" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 6 Nucleoplasm "HPA008859: , HPA011387: " "unprognostic (1.12e-1)" "unprognostic (1.16e-1)" "unprognostic (8.11e-2)" "unprognostic (1.24e-1)" "unprognostic (1.52e-2)" "unprognostic (3.17e-2)" "unprognostic (5.25e-2)" "unprognostic (4.17e-2)" "unprognostic (2.66e-1)" "unprognostic (6.55e-2)" "unprognostic (1.46e-1)" "unprognostic (6.85e-2)" "unprognostic (1.45e-2)" "unprognostic (1.15e-1)" "unprognostic (1.78e-1)" "unprognostic (5.21e-2)" "unprognostic (5.74e-2)" "unprognostic (9.05e-3)" "unprognostic (1.57e-1)" "unprognostic (2.67e-2)" "unprognostic (1.85e-1)" "unprognostic (4.72e-1)" "unprognostic (1.08e-3)" "unprognostic (1.81e-2)" "unprognostic (2.68e-2)" "unprognostic (2.00e-1)" "unprognostic (1.82e-1)" "unprognostic (1.38e-1)" "unprognostic (6.20e-2)" SGK3 "SGK2, SGKL" ENSG00000104205 "Serum/glucocorticoid regulated kinase family member 3" Q96BR1 8 66712734-66862022 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 252.1;Brain inhibitory neurons: 157.4;Choroid plexus epithelial cells: 727.5;Microglia: 234.5;Oligodendrocyte progenitor cells: 138.0;Oligodendrocytes: 458.6;Podocytes: 155.9;Proximal tubule cells: 207.2;Renal collecting duct intercalated cells: 203.5;Retinal pigment epithelial cells: 294.1" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 636.1;oligodendrocyte: 659.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006699, HPA027146" Supported Approved Nucleoplasm,Vesicles NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 9 Vesicles Nucleoplasm "HPA006699: , HPA027146: " "unprognostic (1.64e-1)" "unprognostic (6.94e-3)" "unprognostic (1.52e-1)" "unprognostic (8.79e-2)" "unprognostic (2.12e-1)" "unprognostic (1.64e-1)" "unprognostic (1.29e-1)" "unprognostic (2.83e-1)" "unprognostic (1.82e-2)" "potential prognostic unfavorable (1.46e-4)" "potential prognostic favorable (3.13e-8)" "unprognostic (3.07e-2)" "unprognostic (1.26e-1)" "unprognostic (2.48e-1)" "unprognostic (4.22e-2)" "unprognostic (9.77e-3)" "unprognostic (9.08e-3)" "unprognostic (2.03e-1)" "unprognostic (4.50e-2)" "unprognostic (1.41e-1)" "unprognostic (4.81e-2)" "unprognostic (2.32e-2)" "unprognostic (2.80e-3)" "unprognostic (1.85e-1)" "unprognostic (3.41e-2)" "unprognostic (7.48e-2)" "unprognostic (4.20e-1)" "unprognostic (3.64e-2)" "unprognostic (2.78e-1)" "unprognostic (9.23e-2)" "unprognostic (8.14e-3)" SGMS1 "MGC17342, MOB, SMS1, TMEM23" ENSG00000198964 "Sphingomyelin synthase 1" Q86VZ5 10 50305586-50625163 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Lipid metabolism, Sphingolipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Choroid plexus epithelial cells: 788.5" "Cell type enhanced" "Detected in all" "endothelial cell: 1289.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045191 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus,Cytosol" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 59: Leukemia - T-cell receptor" "Cluster 104: Brain endothelial cells - Blood brain barrier" Nucleoplasm "Nucleoli fibrillar center, Golgi apparatus, Cytosol" "HPA045191: " "unprognostic (1.58e-2)" "unprognostic (3.52e-2)" "unprognostic (9.49e-2)" "unprognostic (1.97e-2)" "unprognostic (2.73e-2)" "unprognostic (1.42e-1)" "unprognostic (1.67e-1)" "potential prognostic favorable (8.97e-4)" "unprognostic (9.16e-2)" "unprognostic (1.52e-1)" "potential prognostic favorable (1.14e-8)" "unprognostic (1.65e-2)" "unprognostic (5.36e-1)" "unprognostic (7.74e-2)" "potential prognostic unfavorable (7.66e-4)" "unprognostic (1.87e-1)" "unprognostic (1.08e-1)" "unprognostic (3.50e-1)" "unprognostic (1.39e-1)" "unprognostic (3.17e-2)" "unprognostic (9.59e-2)" "unprognostic (4.62e-1)" "unprognostic (1.63e-1)" "unprognostic (2.01e-1)" "unprognostic (6.24e-2)" "potential prognostic unfavorable (9.58e-4)" "unprognostic (2.47e-1)" "unprognostic (2.67e-1)" "unprognostic (1.34e-1)" "unprognostic (7.85e-2)" "unprognostic (1.34e-1)" SGMS2 "MGC26963, SMS2" ENSG00000164023 "Sphingomyelin synthase 2" Q8NHU3 4 107824563-107915047 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Kinase, Transferase" "Disease variant, Osteoporosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 511.5;Alveolar cells type 2: 1224.2;Endometrial ciliated cells: 1037.7;Endometrial glandular cells: 1004.0;Endometrial luminal cells: 788.7;Endometrial secretory cells: 539.3;Transitional alveolar cells: 857.4" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 214.4;ependymal cell: 211.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "classical monocyte: 3.7;eosinophil: 2.4;intermediate monocyte: 1.5;myeloid DC: 4.2;non-classical monocyte: 1.4" "Group enriched" "Detected in many" 35 "dendritic cells: 4.2;granulocytes: 2.4;monocytes: 3.7" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Spleen - Neutrophils_2, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015076, HPA015541" Supported Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 13: Lung - Secretion" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 81: Alveolar cells - Lung function" 3 "Golgi apparatus" Nucleoplasm "HPA015076: , HPA015541: " "unprognostic (1.75e-1)" "unprognostic (9.65e-2)" "unprognostic (1.05e-1)" "potential prognostic unfavorable (2.58e-4)" "unprognostic (2.14e-2)" "unprognostic (3.79e-2)" "unprognostic (5.77e-2)" "unprognostic (1.83e-3)" "unprognostic (1.30e-1)" "unprognostic (9.31e-2)" "potential prognostic favorable (3.30e-9)" "unprognostic (3.03e-2)" "unprognostic (7.94e-2)" "unprognostic (8.47e-2)" "unprognostic (5.83e-2)" "unprognostic (7.95e-2)" "unprognostic (1.46e-3)" "unprognostic (1.09e-2)" "unprognostic (7.03e-3)" "unprognostic (6.28e-2)" "unprognostic (1.22e-2)" "potential prognostic unfavorable (1.67e-4)" "unprognostic (1.70e-2)" "unprognostic (2.05e-1)" "unprognostic (8.87e-2)" "unprognostic (2.43e-1)" "unprognostic (2.96e-2)" "unprognostic (1.12e-2)" "unprognostic (8.61e-2)" "unprognostic (6.07e-2)" "unprognostic (1.06e-1)" SGO1 "NY-BR-85, SGOL1" ENSG00000129810 "Shugoshin 1" Q5FBB7 3 20160593-20186206 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 8.2;lymphoid tissue: 12.1;testis: 6.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 41.6;Differentiating spermatogonia: 50.6;Early primary spermatocytes: 65.6;Enteric transient amplifying cells: 40.4;Erythrocyte progenitors: 62.9;Esophageal basal cells: 34.9;Extravillous trophoblasts: 57.3;Gastric progenitor cells: 29.5;Late primary spermatocytes: 44.0;Megakaryocyte progenitors: 44.9;Migrating cytotrophoblasts: 35.0;Monocyte progenitors: 66.8;Oocytes: 124.3;Undifferentiated spermatogonia: 37.0" "Cell type enhanced" "Detected in some" "leukocyte: 2.4;oligodendrocyte: 2.3;oligodendrocyte precursor cell: 3.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 10.2;memory B-cell: 8.9;naive B-cell: 9.0;plasmacytoid DC: 4.2;T-reg: 2.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035501, HPA069302, HPA069857" Enhanced Approved Nucleoplasm,Kinetochore,Cytosol Yes Yes "Cluster 17: B-cells - Immunoglobulins" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 6: Non-specific - Immune response" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Cell proliferation" 26 Nucleoplasm "Kinetochore, Cytosol" "HPA035501: , HPA069302: , HPA069857: " "unprognostic (3.88e-2)" "unprognostic (5.99e-2)" "unprognostic (2.08e-1)" "unprognostic (1.31e-1)" "unprognostic (2.18e-1)" "unprognostic (3.82e-2)" "unprognostic (4.53e-3)" "unprognostic (1.19e-1)" "potential prognostic unfavorable (3.79e-6)" "potential prognostic unfavorable (1.42e-5)" "unprognostic (3.58e-3)" "unprognostic (3.27e-2)" "unprognostic (7.30e-2)" "unprognostic (7.24e-2)" "unprognostic (3.62e-1)" "potential prognostic unfavorable (6.26e-5)" "unprognostic (1.48e-2)" "unprognostic (2.22e-2)" "unprognostic (2.64e-2)" "unprognostic (2.36e-2)" "unprognostic (1.90e-2)" "unprognostic (4.82e-2)" "unprognostic (2.27e-2)" SGO2 "FLJ25211, SGOL2, TRIPIN" ENSG00000163535 "Shugoshin 2" Q562F6 2 200510008-200584096 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Meiosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 13.9;testis: 30.5" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 80.0;Early primary spermatocytes: 267.6;Erythrocyte progenitors: 70.5;Late primary spermatocytes: 327.9;Megakaryocyte progenitors: 72.5;Mesothelial cells: 169.6;Monocyte progenitors: 153.6;Oocytes: 101.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 16.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 16.8" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in many" "HPA035163, HPA040817" Enhanced Enhanced "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 3: Non-specific - Nuclear processes" "Cluster 39: Testis - Nuclear processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 11 Nucleoplasm "Nuclear bodies" "HPA035163: , HPA040817: " "unprognostic (1.04e-3)" "unprognostic (5.38e-2)" "unprognostic (9.65e-2)" "unprognostic (1.43e-2)" "unprognostic (2.89e-1)" "unprognostic (3.65e-1)" "unprognostic (1.53e-1)" "unprognostic (1.44e-1)" "unprognostic (4.54e-2)" "unprognostic (7.54e-3)" "potential prognostic unfavorable (3.68e-4)" "potential prognostic unfavorable (1.28e-5)" "potential prognostic unfavorable (3.02e-5)" "unprognostic (4.96e-3)" "unprognostic (6.78e-3)" "unprognostic (2.83e-1)" "unprognostic (2.76e-1)" "unprognostic (1.67e-1)" "validated prognostic unfavorable (2.88e-4)" "validated prognostic unfavorable (6.97e-4)" "unprognostic (8.10e-2)" "unprognostic (1.10e-1)" "unprognostic (2.62e-1)" "unprognostic (5.60e-2)" "unprognostic (8.64e-2)" "unprognostic (1.05e-1)" "unprognostic (1.20e-1)" SGPL1 SPL ENSG00000166224 "Sphingosine-1-phosphate lyase 1" O95470 10 70815905-70895816 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Lipid metabolism, Sphingolipid metabolism" Lyase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 37.1;Bergmann glia: 38.2;Brain excitatory neurons: 38.2;Brain inhibitory neurons: 34.1;Distal convoluted tubule cells: 62.2;Ependymal cells: 46.8;Loop of henle epithelial cells: 84.9;Microglia: 51.8;Oligodendrocyte progenitor cells: 41.5;Papillary tip epithelial cells: 123.1;Podocytes: 40.0;Proximal tubule cells: 43.2;Renal collecting duct intercalated cells: 67.8;Renal collecting duct principal cells: 89.7;Renal connecting tubule cells: 68.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 138.6" "Pituitary gland - Thyrotropes, Skin - Keratinocyte (granular), Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021125, HPA023086" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 76: Non-specific - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 69 "Endoplasmic reticulum" "HPA021125: , HPA023086: " "unprognostic (6.34e-2)" "unprognostic (5.20e-2)" "unprognostic (2.32e-3)" "unprognostic (4.05e-2)" "unprognostic (2.44e-2)" "unprognostic (1.33e-3)" "unprognostic (1.95e-1)" "potential prognostic favorable (1.34e-4)" "unprognostic (1.85e-1)" "unprognostic (5.82e-2)" "unprognostic (6.75e-3)" "unprognostic (8.36e-2)" "unprognostic (4.17e-1)" "unprognostic (1.36e-2)" "unprognostic (1.68e-1)" "unprognostic (4.34e-2)" "unprognostic (1.91e-2)" "unprognostic (8.90e-2)" "unprognostic (8.98e-2)" "unprognostic (8.02e-2)" "unprognostic (8.37e-2)" "unprognostic (6.20e-3)" "unprognostic (2.17e-1)" "unprognostic (9.82e-2)" "unprognostic (1.70e-1)" "unprognostic (1.37e-1)" "unprognostic (3.40e-1)" "unprognostic (2.21e-1)" "unprognostic (1.35e-1)" "unprognostic (1.74e-1)" "unprognostic (1.27e-1)" SGPP1 ENSG00000126821 "Sphingosine-1-phosphate phosphatase 1" Q9BX95 14 63684216-63728065 "Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bergmann glia: 53.3;Distal convoluted tubule cells: 186.9;Ependymal cells: 45.4;Loop of henle epithelial cells: 46.3;Microglia: 88.9;Oligodendrocyte progenitor cells: 49.1;Oligodendrocytes: 77.4;Papillary tip epithelial cells: 65.5;Proximal tubule cells: 91.3;Renal collecting duct principal cells: 224.7;Renal connecting tubule cells: 381.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 6.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053149, HPA064908" Approved Supported Nucleoplasm NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 36: Brain & Liver - Signaling" "Cluster 30: White matter - Myelination" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 102: Non-specific - Mixed function" 7 Nucleoplasm "HPA053149: , HPA064908: " "unprognostic (2.42e-1)" "unprognostic (8.55e-3)" "unprognostic (1.78e-1)" "potential prognostic unfavorable (5.68e-5)" "unprognostic (6.73e-2)" "unprognostic (5.21e-2)" "unprognostic (1.94e-1)" "unprognostic (7.05e-2)" "unprognostic (3.16e-2)" "unprognostic (2.10e-2)" "potential prognostic favorable (6.33e-6)" "unprognostic (2.40e-2)" "unprognostic (5.74e-3)" "unprognostic (2.66e-3)" "unprognostic (3.41e-1)" "unprognostic (7.52e-3)" "unprognostic (6.27e-3)" "unprognostic (2.72e-2)" "unprognostic (6.27e-2)" "unprognostic (1.58e-1)" "unprognostic (9.78e-3)" "unprognostic (1.50e-1)" "potential prognostic unfavorable (2.67e-4)" "unprognostic (2.82e-1)" "unprognostic (1.52e-1)" "unprognostic (1.21e-1)" "unprognostic (1.52e-1)" "unprognostic (5.45e-2)" "unprognostic (1.25e-1)" "unprognostic (1.25e-1)" "unprognostic (2.16e-1)" SGPP2 "FLJ39004, SPP2" ENSG00000163082 "Sphingosine-1-phosphate phosphatase 2" Q8IWX5 2 222424543-222562621 "Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 1019.4;Endometrial glandular cells: 766.4;Endometrial luminal cells: 423.0;Fallopian secretory cells: 342.8;Transitional alveolar cells: 457.5;Urothelial cells: 600.7" "Cell type enhanced" "Detected in all" "endothelial cell: 370.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 69: Parathyroid gland - Mixed function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 55: Lymphoma - Immune response" "Cluster 51: Secretory epithelial cells - Mixed function" 2 "unprognostic (1.76e-3)" "unprognostic (1.12e-1)" "unprognostic (7.20e-3)" "unprognostic (1.46e-1)" "unprognostic (3.37e-2)" "unprognostic (2.48e-2)" "unprognostic (2.22e-1)" "unprognostic (2.31e-1)" "unprognostic (3.56e-2)" "unprognostic (8.68e-2)" "potential prognostic favorable (2.61e-5)" "unprognostic (2.20e-3)" "unprognostic (1.28e-1)" "potential prognostic unfavorable (6.72e-4)" "unprognostic (6.88e-3)" "unprognostic (1.55e-2)" "unprognostic (3.36e-2)" "unprognostic (2.93e-2)" "unprognostic (2.11e-1)" "unprognostic (1.04e-1)" "unprognostic (1.96e-1)" "unprognostic (5.42e-3)" "unprognostic (5.17e-2)" "unprognostic (8.93e-2)" "unprognostic (8.16e-2)" "unprognostic (6.16e-3)" "unprognostic (3.17e-2)" "unprognostic (9.32e-3)" "unprognostic (1.37e-1)" "unprognostic (7.04e-3)" "unprognostic (2.99e-1)" SGSH "HSS, MPS3A, SFMD" ENSG00000181523 "N-sulfoglucosamine sulfohydrolase" P51688 17 80206716-80220923 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 39.6;Syncytiotrophoblasts: 33.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023436, HPA023451" Enhanced "Intracellular and membrane" Enzyme NA NA 160000 "Cluster 33: Non-specific - ATP binding" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 18: Adrenal cortex cells - Steroidogensis" 18 "HPA023436: , HPA023451: " "unprognostic (1.65e-1)" "unprognostic (1.42e-2)" "unprognostic (1.28e-1)" "unprognostic (6.77e-2)" "unprognostic (5.65e-2)" "unprognostic (3.16e-3)" "unprognostic (2.63e-2)" "unprognostic (2.01e-1)" "unprognostic (1.60e-2)" "unprognostic (3.93e-1)" "unprognostic (4.63e-3)" "unprognostic (8.83e-2)" "unprognostic (3.61e-2)" "unprognostic (2.14e-3)" "unprognostic (2.34e-2)" "unprognostic (4.14e-2)" "unprognostic (7.96e-2)" "unprognostic (2.04e-1)" "unprognostic (1.86e-1)" "unprognostic (1.41e-1)" "unprognostic (3.77e-2)" "unprognostic (5.51e-3)" "unprognostic (3.36e-2)" "unprognostic (2.30e-1)" "unprognostic (1.69e-1)" "unprognostic (6.15e-2)" "unprognostic (1.13e-1)" "unprognostic (4.51e-2)" "unprognostic (6.28e-2)" "unprognostic (7.61e-2)" "unprognostic (1.85e-1)" SGSM1 "KIAA1941, RUTBC2" ENSG00000167037 "Small G protein signaling modulator 1" Q2NKQ1 22 24806169-24927578 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.9;heart muscle: 10.8" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 127.6;Brain excitatory neurons: 142.9;Brain inhibitory neurons: 143.7;Distal convoluted tubule cells: 165.3;Ependymal cells: 162.8;Lactotrophs: 310.0;Other brain neurons: 148.7;Pituitary stem cells: 141.4;Somatotrophs: 128.6;Thyrotrophs: 396.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 6.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 2.9" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Cardiomyocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003986 Approved NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 7 "HPA003986: " "unprognostic (2.63e-1)" "unprognostic (2.45e-1)" "unprognostic (9.30e-2)" "unprognostic (1.68e-1)" "unprognostic (2.36e-2)" "unprognostic (5.81e-2)" "unprognostic (2.19e-1)" "validated prognostic favorable (2.12e-7)" "validated prognostic favorable (6.33e-5)" "unprognostic (1.59e-1)" "unprognostic (3.73e-2)" "unprognostic (6.30e-3)" "unprognostic (1.37e-3)" "unprognostic (7.59e-2)" "unprognostic (1.19e-1)" "unprognostic (1.43e-2)" "unprognostic (1.10e-1)" "unprognostic (3.56e-2)" "unprognostic (1.53e-2)" SGSM2 "KIAA0397, RUTBC1" ENSG00000141258 "Small G protein signaling modulator 2" O43147 17 2337498-2381058 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epicardial cells: 266.1;Epididymal principal cells: 139.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "basophil: 7.1" "Lineage enriched" "Detected in many" 6 "granulocytes: 7.1" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Breast - Breast glandular cells, Colon - Enteric glia cells, Skeletal muscle - Fibroblasts, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021641, HPA024553" Approved Approved Nucleoplasm,Cytosol No No "Cluster 22: Eosinophils - Transcription" "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" 1 "Nucleoplasm, Cytosol" "HPA021641: , HPA024553: " "unprognostic (1.89e-1)" "unprognostic (5.05e-2)" "unprognostic (2.65e-1)" "unprognostic (1.40e-1)" "unprognostic (4.48e-2)" "unprognostic (3.33e-1)" "unprognostic (1.54e-1)" "unprognostic (5.42e-3)" "unprognostic (1.64e-3)" "unprognostic (7.08e-2)" "unprognostic (1.06e-1)" "unprognostic (1.03e-1)" "potential prognostic favorable (9.33e-4)" "unprognostic (4.45e-1)" "unprognostic (1.65e-2)" "unprognostic (6.98e-3)" "unprognostic (4.08e-1)" "unprognostic (9.83e-2)" "unprognostic (9.58e-3)" "unprognostic (1.65e-1)" "unprognostic (1.55e-3)" "potential prognostic favorable (3.01e-6)" "unprognostic (1.30e-2)" "unprognostic (2.29e-2)" "unprognostic (4.55e-1)" "unprognostic (5.80e-2)" "unprognostic (5.61e-2)" "unprognostic (4.79e-2)" "unprognostic (1.82e-1)" "unprognostic (1.16e-1)" "unprognostic (3.71e-1)" SGSM3 "DJ1042K10.2, RabGAP-5, RABGAP5, RUSC3, RUTBC3" ENSG00000100359 "Small G protein signaling modulator 3" Q96HU1 22 40370591-40410289 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell cycle, Growth arrest" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Foveolar cells: 142.9;Goblet cells: 111.7;Mucous neck cells: 44.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048980 Approved Supported "Golgi apparatus" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 70: Intestinal goblet cells - Mucin production" 5 "Golgi apparatus" "HPA048980: " "unprognostic (6.22e-2)" "unprognostic (9.44e-3)" "unprognostic (2.04e-1)" "unprognostic (1.23e-2)" "unprognostic (1.93e-2)" "unprognostic (6.42e-2)" "unprognostic (2.31e-1)" "unprognostic (1.04e-2)" "unprognostic (4.34e-2)" "unprognostic (1.70e-2)" "unprognostic (6.43e-3)" "unprognostic (1.53e-1)" "unprognostic (8.09e-2)" "unprognostic (1.13e-3)" "unprognostic (1.07e-1)" "unprognostic (1.61e-1)" "unprognostic (1.62e-1)" "unprognostic (9.11e-2)" "unprognostic (2.48e-2)" "unprognostic (3.70e-2)" "unprognostic (7.80e-3)" "unprognostic (2.03e-2)" "unprognostic (4.50e-2)" "unprognostic (1.00e-1)" "unprognostic (7.11e-3)" "unprognostic (4.43e-2)" "unprognostic (3.88e-1)" "unprognostic (3.94e-2)" "unprognostic (2.56e-1)" "unprognostic (2.69e-2)" "unprognostic (3.49e-3)" SGTA "alphaSGT, hSGT, SGT, SGT1, UBP, Vpu" ENSG00000104969 "Small glutamine rich tetratricopeptide repeat co-chaperone alpha" O43765 19 2754715-2783362 "Predicted intracellular proteins" "Host-virus interaction" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 130.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056309 Approved Supported Nucleoplasm NA NA 86000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 180 Nucleoplasm "HPA056309: " "unprognostic (3.27e-1)" "unprognostic (2.57e-3)" "unprognostic (8.79e-3)" "unprognostic (5.12e-2)" "unprognostic (3.72e-1)" "unprognostic (1.84e-1)" "unprognostic (9.48e-2)" "unprognostic (2.45e-1)" "unprognostic (6.13e-2)" "unprognostic (1.10e-1)" "unprognostic (1.62e-2)" "unprognostic (1.19e-1)" "unprognostic (9.19e-2)" "unprognostic (3.09e-3)" "unprognostic (4.15e-2)" "potential prognostic unfavorable (7.08e-4)" "unprognostic (5.65e-2)" "unprognostic (6.53e-2)" "unprognostic (2.51e-1)" "unprognostic (1.01e-1)" "unprognostic (3.64e-2)" "unprognostic (1.45e-3)" "unprognostic (1.13e-1)" "unprognostic (2.24e-3)" "unprognostic (2.61e-1)" "unprognostic (4.97e-2)" "unprognostic (2.44e-1)" "unprognostic (1.15e-1)" "unprognostic (1.64e-2)" "unprognostic (1.97e-1)" "unprognostic (3.67e-2)" SGTB "FLJ39002, Sgt2" ENSG00000197860 "Small glutamine rich tetratricopeptide repeat co-chaperone beta" Q96EQ0 5 65665928-65723035 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 30.0" "Cell type enhanced" "Detected in many" "monocytes: 55.9;Müller glia: 77.8;Neutrophil progenitors: 63.1;Neutrophils: 113.8;Retinal horizontal cells: 84.1;T-cells: 49.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 4 "granulocytes: 10.1;monocytes: 6.7;T-cells: 13.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044689, HPA063674" Enhanced Approved "Nucleoplasm,Nuclear speckles,Microtubules,Primary cilium,Basal body" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 73: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 9: T-cells - Adaptive immunity: Regulation" 104 "Nucleoplasm, Primary cilium" "Nuclear speckles, Microtubules, Basal body" "HPA044689: , HPA063674: " "unprognostic (2.38e-1)" "unprognostic (1.70e-1)" "unprognostic (9.88e-2)" "unprognostic (8.01e-3)" "unprognostic (9.85e-2)" "unprognostic (3.49e-2)" "unprognostic (3.81e-1)" "potential prognostic unfavorable (6.94e-4)" "unprognostic (2.73e-1)" "unprognostic (9.66e-3)" "potential prognostic favorable (9.35e-5)" "unprognostic (6.38e-2)" "unprognostic (2.54e-3)" "potential prognostic unfavorable (1.44e-4)" "unprognostic (1.03e-1)" "unprognostic (9.91e-2)" "unprognostic (5.98e-3)" "unprognostic (1.41e-1)" "unprognostic (9.65e-2)" "unprognostic (1.86e-1)" "unprognostic (2.73e-3)" "unprognostic (1.28e-3)" "unprognostic (9.77e-3)" "unprognostic (3.75e-2)" "unprognostic (1.69e-1)" "unprognostic (1.16e-2)" "unprognostic (2.54e-1)" "unprognostic (5.54e-2)" "unprognostic (3.70e-2)" "unprognostic (3.44e-2)" "unprognostic (2.30e-1)" SH2B1 "FLJ30542, SH2B" ENSG00000178188 "SH2B adaptor protein 1" Q9NRF2 16 28846600-28874212 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 118.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060663, HPA076175" Enhanced Approved "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 64: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 54: Non-specific - Transcription" "Cluster 89: Adipocytes - Lipid metabolism" 16 Nucleoplasm "Centriolar satellite, Cytosol" "HPA060663: , HPA076175: " "unprognostic (1.45e-2)" "unprognostic (2.65e-1)" "unprognostic (1.90e-1)" "unprognostic (2.64e-1)" "unprognostic (9.02e-2)" "unprognostic (8.39e-2)" "unprognostic (1.27e-1)" "unprognostic (2.14e-2)" "unprognostic (1.21e-2)" "unprognostic (3.34e-1)" "unprognostic (5.97e-2)" "unprognostic (2.50e-1)" "unprognostic (1.00e-3)" "unprognostic (1.01e-2)" "unprognostic (2.87e-1)" "unprognostic (2.91e-3)" "unprognostic (2.56e-1)" "unprognostic (2.62e-2)" "unprognostic (2.07e-2)" "unprognostic (1.82e-1)" "unprognostic (1.21e-2)" "unprognostic (5.70e-3)" "unprognostic (1.52e-2)" "unprognostic (6.97e-3)" "unprognostic (3.11e-2)" "unprognostic (4.32e-1)" "unprognostic (5.01e-2)" "unprognostic (1.67e-1)" "unprognostic (3.20e-1)" "unprognostic (3.43e-2)" "unprognostic (3.67e-1)" SH2B2 APS ENSG00000160999 "SH2B adaptor protein 2" O14492 7 102285091-102321711 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 33.1" "Cell type enhanced" "Detected in many" "B-cells: 38.5;Extravillous trophoblasts: 105.2;Neutrophils: 205.4;Plasma cells: 37.4;Syncytiotrophoblasts: 82.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 2.9" "Group enriched" "Detected in many" 6 "B-cells: 2.9;granulocytes: 1.6;monocytes: 1.6" "Group enriched" "Detected in all" 5 "lymphoma: 41.7;Myeloma: 52.2" "Spleen - B-cells (Spleen), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051131 Uncertain Approved Cytosol NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 46: Brainstem - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 10 Cytosol "HPA051131: " "unprognostic (1.47e-1)" "unprognostic (1.02e-1)" "unprognostic (1.13e-1)" "unprognostic (2.03e-1)" "unprognostic (1.03e-2)" "unprognostic (2.07e-2)" "unprognostic (2.54e-2)" "unprognostic (9.80e-2)" "unprognostic (2.27e-1)" "potential prognostic unfavorable (2.25e-4)" "unprognostic (5.41e-3)" "unprognostic (2.22e-1)" "unprognostic (5.42e-3)" "potential prognostic unfavorable (9.58e-4)" "unprognostic (1.24e-1)" "unprognostic (2.34e-1)" "unprognostic (2.30e-2)" "unprognostic (1.81e-1)" "unprognostic (2.09e-1)" "unprognostic (3.44e-2)" "unprognostic (2.51e-1)" "unprognostic (3.01e-2)" "unprognostic (4.50e-3)" "unprognostic (6.62e-3)" "unprognostic (1.81e-1)" "unprognostic (8.94e-3)" "unprognostic (2.74e-1)" "unprognostic (1.41e-1)" "unprognostic (2.96e-1)" "unprognostic (1.30e-3)" "unprognostic (2.68e-1)" SH2B3 "IDDM20, LNK" ENSG00000111252 "SH2B adaptor protein 3" Q9UQQ2 12 111405923-111451623 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 57.3" "Cell type enhanced" "Detected in many" "cDC: 297.9;Kupffer cells: 256.2;Macrophages: 272.9;Mast cells: 120.8;Microglia: 153.7;Monocyte progenitors: 123.2;monocytes: 274.7;pDCs: 363.8;Platelets: 145.4" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 193.8;leukocyte: 103.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Spleen - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005483 Approved Approved Nucleoplasm NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 72: Neuronal - Signal transduction" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 6 Nucleoplasm "HPA005483: " "unprognostic (1.35e-1)" "unprognostic (7.36e-2)" "unprognostic (2.78e-1)" "unprognostic (1.47e-1)" "unprognostic (4.39e-1)" "unprognostic (2.82e-1)" "unprognostic (2.09e-1)" "unprognostic (7.26e-2)" "unprognostic (1.04e-1)" "unprognostic (1.59e-1)" "unprognostic (1.53e-3)" "unprognostic (3.09e-3)" "unprognostic (2.02e-1)" "unprognostic (1.18e-1)" "unprognostic (1.48e-3)" "unprognostic (6.09e-2)" "unprognostic (1.30e-3)" "unprognostic (3.18e-3)" "unprognostic (1.02e-1)" "unprognostic (1.38e-2)" "unprognostic (1.80e-2)" "unprognostic (3.00e-2)" "unprognostic (2.16e-3)" "unprognostic (2.47e-1)" "unprognostic (1.45e-1)" "unprognostic (9.25e-3)" "unprognostic (2.87e-1)" "unprognostic (1.75e-1)" "unprognostic (2.83e-2)" "unprognostic (5.75e-2)" "unprognostic (1.24e-1)" SH2D1A "DSHP, EBVS, IMD5, LYP, MTCP1, SAP, XLP, XLPD" ENSG00000183918 "SH2 domain containing 1A" O60880 X 124227868-124373197 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 54 "lymphoid tissue: 200.5" "Cell type enhanced" "Detected in some" "Cholangiocytes: 2.0;NK-cells: 11.7;Platelets: 2.8;T-cells: 12.7;Thymocytes: 3.4" "Cell type enriched" "Detected in single" 47 "leukocyte: 4.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 66 "gdT-cell: 96.7;MAIT T-cell: 126.5;memory CD4 T-cell: 73.1;memory CD8 T-cell: 147.5;naive CD4 T-cell: 76.8;naive CD8 T-cell: 86.7;NK-cell: 128.5;T-reg: 103.3" "Group enriched" "Detected in many" 87 "NK-cells: 128.5;T-cells: 147.5" "Cancer enhanced" "Detected in some" "Leukemia: 26.0;Myeloma: 7.4" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Minor Salivary Gland - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Skeletal muscle - Fibroblasts, Skin - T-cells, Spleen - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA072265 Approved Cytosol NA NA "Cluster 1: T-cells - Unknown function" "Cluster 80: Thymus - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 26 Cytosol "HPA072265: " "unprognostic (1.85e-1)" "unprognostic (1.03e-3)" "unprognostic (1.87e-1)" "potential prognostic favorable (8.22e-4)" "unprognostic (3.25e-1)" "unprognostic (9.85e-2)" "unprognostic (7.62e-2)" "potential prognostic favorable (4.46e-4)" "unprognostic (1.76e-1)" "unprognostic (2.56e-1)" "unprognostic (5.56e-3)" "unprognostic (3.32e-3)" "unprognostic (1.83e-1)" "unprognostic (2.28e-1)" "unprognostic (3.98e-1)" "unprognostic (2.71e-1)" "unprognostic (1.50e-2)" "unprognostic (8.97e-2)" "unprognostic (2.56e-1)" "unprognostic (4.27e-2)" "unprognostic (1.11e-1)" "unprognostic (3.07e-2)" "unprognostic (1.95e-1)" SH2D1B EAT2 ENSG00000198574 "SH2 domain containing 1B" O14796 1 162395268-162412138 "Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 7.1;skeletal muscle: 11.4;tongue: 6.1" "Group enriched" "Detected in some" 4 "Innate lymphoid cells: 42.5;NK-cells: 167.4" "Cell type enriched" "Detected in some" 6 "leukocyte: 45.7" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 8 "NK-cell: 377.4;non-classical monocyte: 149.7" "Group enriched" "Detected in many" 38 "monocytes: 149.7;NK-cells: 377.4" "Cancer enriched" "Detected in single" 6 "lymphoma: 4.7" "Adipose visceral - T-cells, Heart muscle - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Spleen - NK-cells (Spleen)" "Not detected" "Not detected" HPA054791 Uncertain NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 53: Neurons - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 20 "HPA054791: " "unprognostic (1.50e-1)" "unprognostic (3.03e-1)" SH2D2A "F2771, TSAd" ENSG00000027869 "SH2 domain containing 2A" Q9NP31 1 156806243-156816848 "Predicted intracellular proteins" "Angiogenesis, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 13.8" "Cell type enhanced" "Detected in some" "Decidual stromal cells: 26.4;Innate lymphoid cells: 17.1;NK-cells: 125.2;Retinal bipolar cells: 24.1;T-cells: 79.2" "Cell type enriched" "Detected in some" 10 "leukocyte: 48.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 30 "NK-cells: 28.5;T-cells: 66.6" "Group enriched" "Detected in many" 6 "Leukemia: 13.3;lymphoma: 27.3;Myeloma: 13.0" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Lung - NK-cells (Lung), Minor Salivary Gland - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "cerebral cortex: 4.6;hippocampal formation: 2.1" HPA074482 Enhanced NA NA "Cluster 1: T-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 43 "HPA074482: " "unprognostic (3.47e-2)" "potential prognostic favorable (8.33e-4)" "unprognostic (3.19e-2)" "unprognostic (1.64e-1)" "unprognostic (7.36e-2)" "unprognostic (1.26e-1)" "potential prognostic unfavorable (6.02e-6)" "unprognostic (1.37e-3)" "unprognostic (8.32e-2)" "potential prognostic unfavorable (3.52e-4)" "unprognostic (1.02e-1)" "unprognostic (7.53e-3)" "unprognostic (2.19e-1)" "unprognostic (1.77e-2)" "unprognostic (2.44e-1)" "unprognostic (2.05e-2)" "unprognostic (1.79e-1)" "unprognostic (8.42e-2)" "unprognostic (1.95e-1)" "unprognostic (2.29e-1)" "unprognostic (9.30e-3)" "unprognostic (2.27e-2)" "unprognostic (1.46e-1)" "unprognostic (2.12e-1)" "unprognostic (1.23e-3)" "unprognostic (2.45e-1)" "unprognostic (1.88e-1)" "unprognostic (7.98e-2)" "unprognostic (1.20e-1)" "unprognostic (1.49e-2)" SH2D3A NSP1 ENSG00000125731 "SH2 domain containing 3A" Q9BRG2 19 6752160-6767463 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 31.2" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 155.7;Extravillous trophoblasts: 85.6;Urothelial cells: 114.0" "Cell type enriched" "Detected in some" 6 "leukocyte: 12.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose visceral - T-cells, Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "HPA035722, HPA064382" Uncertain Approved "Nucleoplasm,Microtubules,Cytokinetic bridge" Yes NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 60: Stomach - Digestion" "Cluster 6: Non-specific - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 54 Microtubules "Nucleoplasm, Cytokinetic bridge" "HPA035722: , HPA064382: " "unprognostic (1.52e-1)" "unprognostic (2.45e-2)" "unprognostic (1.10e-1)" "unprognostic (1.30e-2)" "unprognostic (3.37e-2)" "unprognostic (1.62e-1)" "unprognostic (5.02e-2)" "unprognostic (8.77e-3)" "potential prognostic favorable (3.76e-5)" "unprognostic (1.87e-2)" "unprognostic (1.26e-1)" "unprognostic (1.70e-1)" "unprognostic (4.19e-2)" "potential prognostic unfavorable (3.22e-4)" "unprognostic (1.87e-1)" "unprognostic (1.67e-1)" "unprognostic (7.41e-2)" "unprognostic (2.44e-2)" "unprognostic (3.42e-1)" "unprognostic (4.01e-3)" "unprognostic (6.20e-2)" "unprognostic (2.02e-3)" "unprognostic (5.25e-2)" "unprognostic (1.56e-2)" "unprognostic (2.69e-1)" "unprognostic (2.96e-2)" "unprognostic (2.59e-1)" "unprognostic (5.15e-3)" "unprognostic (3.76e-2)" SH2D3C NSP3 ENSG00000095370 "SH2 domain containing 3C" Q8N5H7 9 127738317-127778710 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 85.1;B-cells: 50.0;Lymphatic endothelial cells: 135.8;Monocyte progenitors: 61.1;monocytes: 59.5;Neutrophil progenitors: 51.4;Neutrophils: 320.1;pDCs: 172.8;Thymocytes: 90.6;Vascular endothelial cells: 126.3" "Cell type enhanced" "Detected in many" "endothelial cell: 132.3;leukocyte: 118.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 13 "Leukemia: 34.2;lymphoma: 24.0;Myeloma: 27.0;Neuroblastoma: 15.7" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Pancreas - Endothelial cells, Pituitary gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047586 Enhanced Supported Cytosol NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 5: Spleen - Immune response" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 24: Neutrophils - Innate immunity signal integration" 7 Cytosol "HPA047586: " "unprognostic (5.07e-3)" "unprognostic (7.83e-2)" "unprognostic (5.30e-2)" "unprognostic (6.71e-2)" "unprognostic (1.61e-2)" "unprognostic (1.83e-1)" "unprognostic (3.37e-2)" "unprognostic (1.54e-1)" "potential prognostic favorable (8.67e-4)" "unprognostic (1.87e-1)" "potential prognostic favorable (4.98e-4)" "unprognostic (2.54e-3)" "unprognostic (5.73e-3)" "unprognostic (8.11e-2)" "unprognostic (5.08e-3)" "unprognostic (9.57e-2)" "unprognostic (2.95e-1)" "unprognostic (8.48e-3)" "unprognostic (3.10e-1)" "unprognostic (6.97e-2)" "unprognostic (1.11e-1)" "unprognostic (1.94e-3)" "unprognostic (5.62e-2)" "unprognostic (1.26e-1)" "unprognostic (1.42e-1)" "unprognostic (9.36e-2)" "unprognostic (1.59e-1)" "unprognostic (1.01e-1)" "unprognostic (5.09e-2)" "unprognostic (1.87e-1)" "unprognostic (1.50e-2)" SH2D4A "FLJ20967, PPP1R38, SH2A" ENSG00000104611 "SH2 domain containing 4A" Q9H788 8 19313693-19396218 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 153.0;Oocytes: 211.8;Renal collecting duct intercalated cells: 169.0;Salivary duct cells: 181.5;Salivary ionocytes: 141.9" "Cell type enhanced" "Detected in many" "oligodendrocyte precursor cell: 25.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.8" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Pituitary gland - Undifferentiated cells (Pituitary gland), Skeletal muscle - Fibroblasts" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001871, HPA001919" Enhanced Enhanced Cytosol NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 86 Cytosol "HPA001871: , HPA001919: " "potential prognostic favorable (2.56e-4)" "unprognostic (2.24e-1)" "unprognostic (9.64e-2)" "unprognostic (5.07e-2)" "potential prognostic favorable (4.37e-4)" "unprognostic (1.28e-1)" "validated prognostic unfavorable (7.16e-4)" "validated prognostic unfavorable (5.52e-6)" "unprognostic (6.87e-3)" "potential prognostic unfavorable (3.45e-5)" "potential prognostic favorable (3.90e-6)" "unprognostic (6.11e-3)" "unprognostic (5.17e-3)" "unprognostic (5.43e-1)" "unprognostic (2.97e-1)" "unprognostic (1.19e-1)" "unprognostic (8.97e-3)" "unprognostic (3.03e-1)" "unprognostic (2.25e-1)" "unprognostic (5.07e-3)" "unprognostic (7.40e-3)" "potential prognostic unfavorable (2.31e-4)" "unprognostic (6.72e-2)" "unprognostic (1.45e-1)" "unprognostic (2.41e-2)" "unprognostic (1.54e-1)" "unprognostic (7.14e-2)" "unprognostic (1.60e-2)" "unprognostic (2.96e-1)" "unprognostic (1.89e-2)" "unprognostic (3.17e-2)" SH2D4B ENSG00000178217 "SH2 domain containing 4B" Q5SQS7 10 80537902-80646560 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "Early spermatids: 8.7;Endometrial glandular cells: 9.2;Endometrial luminal cells: 13.5;Endometrial secretory cells: 25.9;Epididymal basal cells: 9.9;Epididymal clear cells: 34.7;Late primary spermatocytes: 12.0;Neutrophils: 10.4;Undifferentiated spermatogonia: 10.8" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 18 "Leukemia: 2.4;lymphoma: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA040022 Uncertain NA NA "Cluster 6: Leukemia - Signal transduction" "Cluster 51: Secretory epithelial cells - Mixed function" "HPA040022: " SH2D5 ENSG00000189410 "SH2 domain containing 5" Q6ZV89 1 20719731-20732837 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 16.8;testis: 6.9" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 3.9;Brain excitatory neurons: 7.3;Brain inhibitory neurons: 13.8;Epicardial cells: 4.5;Other brain neurons: 6.3;Retinal amacrine cells: 3.4;Syncytiotrophoblasts: 7.3" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Head and Neck Squamous Cell Carcinoma (TCGA): 6.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA030182 Approved Cytosol NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 35: Neurons - Synaptic function & neurogenesis" Cytosol "HPA030182: " "unprognostic (1.29e-1)" "unprognostic (7.85e-3)" "unprognostic (8.94e-2)" "unprognostic (5.47e-2)" "unprognostic (1.06e-1)" "unprognostic (2.90e-2)" "unprognostic (3.80e-1)" "unprognostic (3.59e-1)" "unprognostic (6.86e-2)" SH2D6 "FLJ35993, SLNK" ENSG00000152292 "SH2 domain containing 6" 2 85418714-85437029 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "intestine: 2.8;testis: 1.7" "Cell type enriched" "Detected in some" 230 "Tuft cells: 2709.1" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA053873 Uncertain NA NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 6: Non-specific - Immune response" "Cluster 24: Non-specific - Unknown function" "Cluster 95: Tuft cells - Chemosensory signaling" "HPA053873: " "unprognostic (9.11e-3)" "unprognostic (1.15e-1)" SH2D7 LOC646892 ENSG00000183476 "SH2 domain containing 7" A6NKC9 15 78077808-78104370 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 9 "intestine: 2.2;testis: 2.9" "Cell type enhanced" "Detected in some" "Early spermatids: 242.8;Late primary spermatocytes: 393.2;Late spermatids: 224.9;Tuft cells: 1003.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Uterine Corpus Endometrial Carcinoma (TCGA): 1.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "skin cancer: 1.9" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA051320, HPA058382, HPA076728" Enhanced Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 21: Testis - Mixed function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 95: Tuft cells - Chemosensory signaling" Nucleoli "Nucleoplasm, Cytosol" "HPA051320: , HPA058382: , HPA076728: " "unprognostic (3.27e-1)" SH3BGR 21-GARP ENSG00000185437 "SH3 domain binding glutamate rich protein" P55822 21 39445855-39515506 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "skeletal muscle: 1188.4;tongue: 573.1" "Cell type enhanced" "Detected in some" "Astrocytes: 28.7;Bergmann glia: 15.3;Brain excitatory neurons: 9.1;Brain inhibitory neurons: 11.9;Choroid plexus epithelial cells: 24.1;Distal convoluted tubule cells: 15.1;Ependymal cells: 38.1;Loop of henle epithelial cells: 11.3;Oligodendrocyte progenitor cells: 11.0;Oligodendrocytes: 24.7;Other brain neurons: 9.0;Podocytes: 9.0;Proximal tubule cells: 8.4;Renal collecting duct principal cells: 7.4;Renal connecting tubule cells: 11.5" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 56.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 3.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Breast myoepithelial cells, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Group enriched" "Detected in all" 5 "cerebellum: 30.5;midbrain: 12.2;olfactory bulb: 9.9;pons and medulla: 31.9" "Low region specificity" "Detected in all" CAB003685 Enhanced Approved "Plasma membrane,Cytosol" NA NA 7700 "Cluster 30: Non-specific - DNA binding" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 28: Astrocytes - Homeostasis & neuron support" 1 "Plasma membrane, Cytosol" "CAB003685: " "unprognostic (9.32e-3)" "unprognostic (6.06e-3)" "unprognostic (8.49e-2)" "unprognostic (2.74e-1)" "unprognostic (1.43e-1)" "unprognostic (1.23e-1)" "unprognostic (3.87e-2)" "potential prognostic unfavorable (4.41e-4)" "unprognostic (2.40e-3)" "unprognostic (1.64e-2)" "unprognostic (4.69e-2)" "unprognostic (2.83e-1)" "unprognostic (3.35e-2)" "unprognostic (7.55e-2)" "unprognostic (1.71e-1)" "unprognostic (1.60e-1)" "unprognostic (2.11e-1)" "unprognostic (1.90e-1)" "unprognostic (8.52e-2)" "unprognostic (5.56e-2)" "unprognostic (1.44e-1)" "unprognostic (8.68e-2)" "unprognostic (1.97e-1)" "unprognostic (3.24e-1)" "unprognostic (7.62e-2)" "unprognostic (1.39e-2)" "unprognostic (6.13e-2)" "unprognostic (3.63e-3)" "unprognostic (1.79e-1)" "unprognostic (1.99e-2)" "unprognostic (5.79e-2)" SH3BGRL MGC117402 ENSG00000131171 "SH3 domain binding glutamate rich protein like" O75368 X 81202102-81298547 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 615.2;Platelets: 793.2;Smooth muscle cells: 620.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030507, HPA051248" Approved Supported Cytosol NA NA 12000000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 27: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 62: Smooth muscle cells - Muscle contraction" 5 Cytosol "HPA030507: , HPA051248: " "potential prognostic favorable (3.50e-5)" "unprognostic (2.55e-2)" "unprognostic (2.86e-1)" "unprognostic (1.37e-1)" "unprognostic (1.86e-1)" "unprognostic (1.48e-2)" "unprognostic (2.96e-1)" "unprognostic (2.08e-1)" "unprognostic (1.13e-1)" "unprognostic (2.13e-1)" "potential prognostic favorable (7.91e-8)" "unprognostic (2.86e-1)" "unprognostic (9.60e-2)" "unprognostic (3.26e-2)" "unprognostic (7.15e-2)" "unprognostic (1.81e-2)" "unprognostic (2.15e-1)" "unprognostic (3.77e-2)" "unprognostic (7.81e-3)" "unprognostic (1.36e-1)" "unprognostic (2.79e-3)" "unprognostic (2.44e-1)" "unprognostic (2.03e-1)" "unprognostic (7.94e-2)" "unprognostic (2.82e-1)" "unprognostic (1.24e-1)" "unprognostic (4.40e-2)" "unprognostic (1.70e-3)" "unprognostic (6.93e-2)" "unprognostic (2.75e-1)" "unprognostic (6.94e-2)" SH3BGRL2 ENSG00000198478 "SH3 domain binding glutamate rich protein like 2" Q9UJC5 6 79631329-79703655 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 152.3" "Group enriched" "Detected in many" 4 "Esophageal apical cells: 1068.6;Platelets: 950.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Thyroid Carcinoma (TCGA): 74.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "basophil: 11.0" "Lineage enriched" "Detected in many" 10 "granulocytes: 11.0" "Cancer enhanced" "Detected in many" "colorectal cancer: 34.5" "Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Liver - Hepatocytes, Skeletal muscle - Endothelial cells, Stomach - Gastric mucous cells, Testis - Endothelial cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047486 Approved Supported Nucleoplasm NA NA 2300000 "Cluster 21: Neutrophils - Unknown function" "Cluster 60: Stomach - Digestion" "Cluster 24: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 84: Apical squamous epithelium - Cornification" 2 Nucleoplasm "HPA047486: " "unprognostic (9.69e-2)" "unprognostic (5.16e-2)" "unprognostic (2.69e-1)" "unprognostic (4.59e-1)" "unprognostic (8.63e-3)" "unprognostic (1.61e-1)" "unprognostic (2.54e-1)" "unprognostic (2.37e-2)" "unprognostic (1.46e-1)" "unprognostic (3.07e-2)" "validated prognostic favorable (9.13e-11)" "validated prognostic favorable (2.38e-4)" "unprognostic (2.98e-1)" "unprognostic (2.96e-1)" "unprognostic (3.07e-2)" "unprognostic (1.60e-2)" "unprognostic (1.13e-1)" "unprognostic (1.77e-1)" "unprognostic (8.63e-2)" "unprognostic (5.94e-2)" "unprognostic (2.31e-2)" "unprognostic (6.61e-2)" "unprognostic (2.77e-1)" "unprognostic (2.54e-2)" "unprognostic (8.59e-2)" "potential prognostic unfavorable (4.63e-5)" "unprognostic (7.31e-2)" "unprognostic (2.23e-1)" "unprognostic (1.59e-1)" "unprognostic (5.81e-2)" "unprognostic (6.97e-3)" SH3BGRL3 ENSG00000142669 "SH3 domain binding glutamate rich protein like 3" Q9H299 1 26280086-26281522 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 1845.5;Epididymal principal cells: 2052.6;Esophageal apical cells: 5483.2;Esophageal suprabasal cells: 3161.7;Hofbauer cells: 2083.5;Megakaryocytes: 6058.0;monocytes: 2333.5;Platelets: 11941.1" "Cell type enhanced" "Detected in all" "leukocyte: 215.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030848, HPA076219" Enhanced Approved "Nuclear bodies" NA NA 65000000 "Cluster 29: Non-specific - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 47: Platelets - Hemostasis" 4 "Nuclear bodies" "HPA030848: , HPA076219: " "unprognostic (7.95e-2)" "unprognostic (3.82e-2)" "unprognostic (3.16e-2)" "unprognostic (9.77e-2)" "unprognostic (6.98e-2)" "unprognostic (3.40e-3)" "unprognostic (1.68e-2)" "unprognostic (1.45e-2)" "unprognostic (1.49e-1)" "unprognostic (6.30e-2)" "potential prognostic unfavorable (1.57e-7)" "unprognostic (3.95e-3)" "unprognostic (1.97e-1)" "unprognostic (7.89e-3)" "unprognostic (4.21e-2)" "unprognostic (1.15e-2)" "unprognostic (2.41e-3)" "unprognostic (4.00e-1)" "unprognostic (5.47e-2)" "unprognostic (2.53e-1)" "unprognostic (2.33e-1)" "unprognostic (1.31e-2)" "unprognostic (6.91e-2)" "unprognostic (3.05e-1)" "potential prognostic unfavorable (4.10e-4)" "unprognostic (4.60e-2)" "unprognostic (1.57e-1)" "unprognostic (1.72e-1)" "unprognostic (3.20e-2)" "unprognostic (1.95e-1)" "unprognostic (1.76e-1)" SH3BP1 ARHGAP43 ENSG00000100092 "SH3 domain binding protein 1" Q9Y3L3 22 37634654-37656117 "Metabolic proteins, Predicted intracellular proteins" Phagocytosis "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 38.9" "Cell type enriched" "Detected in some" 5 "Microglia: 35.2" "Group enriched" "Detected in many" 4 "central nervous system macrophage: 45.0;leukocyte: 46.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Macrophages, Skin - Keratinocyte (other), Spleen - T-cells, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA000757 Supported Supported Cytosol NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 102: Non-specific - Mixed function" 14 Cytosol "HPA000757: " "unprognostic (9.10e-2)" "unprognostic (4.08e-3)" "unprognostic (7.68e-2)" "unprognostic (9.70e-2)" "unprognostic (1.99e-1)" "unprognostic (8.43e-2)" "unprognostic (1.53e-1)" "unprognostic (1.10e-1)" "unprognostic (1.86e-1)" "unprognostic (1.98e-1)" "unprognostic (5.98e-3)" "unprognostic (1.16e-1)" "unprognostic (8.90e-3)" "unprognostic (2.65e-3)" "unprognostic (7.56e-2)" "unprognostic (3.05e-1)" "unprognostic (8.83e-2)" "unprognostic (2.90e-2)" "unprognostic (1.26e-2)" "unprognostic (2.15e-1)" "unprognostic (1.16e-1)" "unprognostic (6.64e-2)" "unprognostic (8.06e-3)" "unprognostic (1.20e-1)" "unprognostic (1.68e-1)" "unprognostic (1.57e-1)" "unprognostic (4.07e-1)" "potential prognostic favorable (9.71e-5)" "unprognostic (2.71e-1)" "unprognostic (2.25e-1)" "unprognostic (1.67e-1)" SH3BP2 "CRBM, RES4-23" ENSG00000087266 "SH3 domain binding protein 2" P78314 4 2793071-2841098 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Kupffer cells: 86.1;monocytes: 133.2;Neutrophils: 180.0;Proximal tubule cells: 169.8" "Group enriched" "Detected in many" 4 "astrocyte: 94.9;Bergmann glia: 60.0;central nervous system macrophage: 71.0;endothelial cell: 26.8;leukocyte: 63.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Macrophages, Pituitary gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036789, HPA036790" Approved Approved "Golgi apparatus" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 58: Skin - Keratinization" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 20 "Golgi apparatus" "HPA036789: , HPA036790: " "unprognostic (7.10e-3)" "unprognostic (2.93e-2)" "potential prognostic favorable (5.96e-4)" "unprognostic (1.26e-1)" "unprognostic (1.27e-2)" "unprognostic (1.68e-1)" "unprognostic (1.29e-3)" "unprognostic (8.49e-2)" "unprognostic (8.03e-3)" "unprognostic (3.82e-2)" "validated prognostic favorable (4.16e-6)" "validated prognostic favorable (4.37e-4)" "unprognostic (1.62e-1)" "unprognostic (7.23e-2)" "unprognostic (1.37e-3)" "unprognostic (1.78e-3)" "unprognostic (1.86e-2)" "unprognostic (2.50e-2)" "unprognostic (1.04e-1)" "unprognostic (1.71e-2)" "unprognostic (3.93e-2)" "unprognostic (1.68e-2)" "potential prognostic unfavorable (6.60e-4)" "unprognostic (6.45e-3)" "unprognostic (8.98e-2)" "unprognostic (1.01e-1)" "unprognostic (1.16e-1)" "unprognostic (1.40e-1)" "unprognostic (5.04e-2)" "unprognostic (3.24e-1)" "unprognostic (1.63e-1)" SH3BP4 ENSG00000130147 "SH3 domain binding protein 4" Q9P0V3 2 234952017-235055714 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 78.6" "Cell type enhanced" "Detected in many" "Breast lactating cells: 295.4;Epididymal clear cells: 200.0;Lacrimal acinar cells: 248.2;Pancreatic acinar cells: 201.7;Renal collecting duct intercalated cells: 231.6;Salivary acinar cells: 375.2" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 159.4;endothelial cell: 180.5;oligodendrocyte: 103.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 14 "basophil: 1.0;myeloid DC: 2.0;plasmacytoid DC: 3.1" "Group enriched" "Detected in many" 14 "dendritic cells: 3.1;granulocytes: 1.0" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037533, HPA037534" Uncertain NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 60: Stomach - Digestion" "Cluster 6: Non-specific - Immune response" "Cluster 72: Neuronal - Signal transduction" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 46 "HPA037533: , HPA037534: " "unprognostic (2.40e-2)" "unprognostic (2.85e-3)" "unprognostic (1.57e-1)" "unprognostic (2.82e-1)" "unprognostic (3.58e-1)" "unprognostic (1.67e-1)" "unprognostic (1.15e-1)" "unprognostic (7.44e-2)" "unprognostic (2.36e-1)" "unprognostic (8.51e-3)" "validated prognostic favorable (3.18e-7)" "validated prognostic favorable (2.05e-4)" "unprognostic (1.54e-2)" "unprognostic (1.12e-1)" "unprognostic (3.41e-1)" "unprognostic (7.11e-2)" "unprognostic (2.69e-1)" "unprognostic (1.96e-1)" "unprognostic (2.44e-2)" "unprognostic (9.98e-3)" "unprognostic (7.03e-2)" "unprognostic (1.23e-1)" "unprognostic (1.40e-1)" "unprognostic (2.61e-1)" "unprognostic (1.62e-1)" "unprognostic (1.50e-1)" "unprognostic (2.68e-2)" "unprognostic (3.49e-2)" "unprognostic (7.37e-2)" "unprognostic (1.45e-2)" "unprognostic (4.90e-1)" SH3BP5 Sab ENSG00000131370 "SH3 domain binding protein 5" O60239 3 15254353-15341368 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 806.2;Early spermatids: 302.6;Extravillous trophoblasts: 618.5;monocytes: 351.7;Neutrophils: 795.1;Syncytiotrophoblasts: 298.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036445, HPA057988" Uncertain Enhanced "Nucleoplasm,Nuclear bodies" No No "Cluster 24: Non-specific - Transcription" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 34: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 12 "Nucleoplasm, Nuclear bodies" "HPA036445: , HPA057988: " "unprognostic (1.98e-2)" "potential prognostic favorable (2.74e-4)" "unprognostic (1.70e-2)" "unprognostic (1.66e-1)" "unprognostic (9.93e-2)" "unprognostic (2.49e-2)" "unprognostic (1.86e-1)" "unprognostic (1.52e-1)" "unprognostic (5.36e-3)" "unprognostic (1.61e-1)" "potential prognostic favorable (4.40e-7)" "unprognostic (1.20e-3)" "unprognostic (1.55e-2)" "unprognostic (9.65e-3)" "unprognostic (5.51e-3)" "potential prognostic favorable (4.19e-4)" "unprognostic (3.01e-1)" "unprognostic (4.77e-1)" "unprognostic (1.88e-1)" "unprognostic (4.29e-2)" "unprognostic (1.21e-3)" "unprognostic (3.18e-1)" "unprognostic (2.20e-1)" "unprognostic (2.80e-1)" "unprognostic (1.86e-1)" "unprognostic (2.43e-3)" "unprognostic (1.25e-1)" "unprognostic (1.26e-1)" "unprognostic (1.10e-1)" "unprognostic (6.61e-2)" "unprognostic (2.90e-2)" SH3BP5L KIAA1720 ENSG00000175137 "SH3 binding domain protein 5 like" Q7L8J4 1 248810446-248825915 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 52.9;Neutrophils: 34.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 7.7;eosinophil: 4.1;neutrophil: 4.7" "Lineage enriched" "Detected in many" 6 "granulocytes: 7.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038067, HPA038068" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 21 "Nucleoplasm, Golgi apparatus, Vesicles" "HPA038067: , HPA038068: " "unprognostic (2.42e-1)" "unprognostic (1.15e-1)" "unprognostic (8.13e-2)" "unprognostic (3.29e-3)" "unprognostic (3.23e-1)" "unprognostic (2.55e-3)" "unprognostic (2.37e-1)" "unprognostic (1.94e-3)" "unprognostic (2.40e-3)" "unprognostic (2.38e-1)" "potential prognostic favorable (5.69e-4)" "unprognostic (2.29e-1)" "unprognostic (1.55e-3)" "potential prognostic unfavorable (8.93e-4)" "unprognostic (3.50e-1)" "unprognostic (8.35e-2)" "potential prognostic unfavorable (6.38e-4)" "unprognostic (8.58e-2)" "unprognostic (2.63e-1)" "unprognostic (3.36e-1)" "unprognostic (1.72e-1)" "unprognostic (3.98e-2)" "unprognostic (1.86e-1)" "unprognostic (2.79e-3)" "unprognostic (1.53e-1)" "unprognostic (8.98e-2)" "unprognostic (3.32e-1)" "unprognostic (7.13e-2)" "unprognostic (4.34e-2)" "unprognostic (7.74e-2)" "unprognostic (2.59e-1)" SH3D19 "DKFZp434D0215, EBP, Eve-1, EVE1, Kryn, SH3P19" ENSG00000109686 "SH3 domain containing 19" Q5HYK7 4 151102751-151325605 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 2919.5;Fibro-adipogenic progenitors: 885.7" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 2515.4" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "choroid plexus: 238.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Liver - Hepatocytes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016424, HPA058562" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 17 "Nucleoplasm, Cytosol" "HPA016424: , HPA058562: " "unprognostic (1.39e-1)" "unprognostic (2.44e-2)" "unprognostic (1.30e-1)" "potential prognostic unfavorable (5.84e-4)" "unprognostic (3.76e-2)" "unprognostic (1.26e-1)" "unprognostic (1.05e-1)" "unprognostic (1.14e-1)" "unprognostic (5.87e-2)" "unprognostic (2.12e-3)" "validated prognostic favorable (1.35e-10)" "validated prognostic favorable (2.31e-4)" "unprognostic (8.67e-2)" "unprognostic (1.20e-1)" "unprognostic (4.73e-3)" "unprognostic (2.63e-1)" "unprognostic (6.41e-2)" "unprognostic (2.54e-2)" "unprognostic (3.73e-2)" "unprognostic (4.68e-2)" "unprognostic (3.70e-3)" "unprognostic (3.98e-3)" "unprognostic (9.35e-2)" "unprognostic (2.37e-1)" "unprognostic (2.24e-2)" "unprognostic (1.77e-1)" "unprognostic (3.97e-2)" "unprognostic (1.52e-1)" "unprognostic (2.34e-1)" "unprognostic (6.62e-2)" "unprognostic (1.51e-1)" SH3D21 "C1orf113, FLJ22938" ENSG00000214193 "SH3 domain containing 21" A4FU49 1 36306368-36329340 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 32.8" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 39.0;Enterocytes: 36.2;Esophageal apical cells: 33.4;Late spermatids: 90.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Stomach - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA042212, HPA042456, HPA066168" Approved Approved "Nucleoplasm,Plasma membrane,Basal body" NA NA "Cluster 58: Skin - Keratinization" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 1 "Plasma membrane" "Nucleoplasm, Basal body" "HPA042212: , HPA042456: , HPA066168: " "unprognostic (1.23e-1)" "unprognostic (1.43e-3)" "unprognostic (2.69e-2)" "unprognostic (1.20e-1)" "unprognostic (2.51e-1)" "unprognostic (2.28e-3)" "unprognostic (2.88e-1)" "unprognostic (2.91e-2)" "unprognostic (1.27e-3)" "unprognostic (1.25e-2)" "unprognostic (5.12e-2)" "unprognostic (6.30e-2)" "unprognostic (2.25e-2)" "unprognostic (1.15e-1)" "unprognostic (1.59e-2)" "unprognostic (2.88e-1)" "unprognostic (1.46e-1)" "unprognostic (3.95e-2)" "unprognostic (3.12e-2)" "unprognostic (1.41e-2)" "unprognostic (2.52e-2)" "unprognostic (1.67e-1)" "unprognostic (1.02e-2)" "unprognostic (8.03e-2)" "unprognostic (3.62e-2)" "unprognostic (8.19e-2)" "unprognostic (2.68e-1)" "unprognostic (1.21e-1)" "unprognostic (2.88e-1)" SH3GL1 "CNSA1, EEN, MGC111371, SH3D2B, SH3P8" ENSG00000141985 "SH3 domain containing GRB2 like 1, endophilin A2" Q99961 19 4360370-4400547 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" Endocytosis "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Esophageal apical cells: 1037.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021485 Approved Supported Cytosol NA NA 16000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 34: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 84: Apical squamous epithelium - Cornification" 49 Cytosol "HPA021485: " "unprognostic (5.28e-2)" "unprognostic (8.15e-2)" "unprognostic (2.92e-1)" "unprognostic (1.60e-1)" "unprognostic (3.94e-2)" "unprognostic (4.06e-2)" "unprognostic (1.16e-1)" "unprognostic (3.54e-1)" "unprognostic (8.54e-2)" "unprognostic (3.72e-2)" "unprognostic (3.82e-2)" "unprognostic (1.41e-1)" "unprognostic (2.89e-2)" "potential prognostic unfavorable (4.37e-5)" "unprognostic (2.27e-3)" "potential prognostic unfavorable (1.85e-5)" "unprognostic (3.64e-2)" "unprognostic (1.31e-1)" "unprognostic (3.37e-1)" "unprognostic (2.02e-1)" "unprognostic (2.00e-1)" "unprognostic (1.21e-1)" "unprognostic (2.92e-2)" "unprognostic (1.10e-2)" "unprognostic (1.91e-1)" "potential prognostic favorable (9.13e-4)" "unprognostic (2.63e-1)" "unprognostic (3.14e-2)" "unprognostic (2.33e-1)" "unprognostic (1.09e-1)" "unprognostic (6.34e-3)" SH3GL2 "CNSA2, EEN-B1, SH3D2A, SH3P4" ENSG00000107295 "SH3 domain containing GRB2 like 2, endophilin A1" Q99962 9 17579066-17797124 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 227.8;retina: 69.5" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 549.9;Brain inhibitory neurons: 235.6;Cone photoreceptor cells: 443.0;Corticotrophs: 316.8;Gonadotrophs: 157.7;Lactotrophs: 254.6;Pancreatic islet cells: 199.8;Proximal tubule cells: 160.3;Retinal amacrine cells: 243.1;Retinal bipolar cells: 470.0;Retinal ganglion cells: 170.0;Rod photoreceptor cells: 171.5;Somatotrophs: 241.1;Thyrotrophs: 263.9" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Glioblastoma Multiforme (TCGA): 13.4;Kidney Chromophobe (TCGA): 8.8;Kidney Renal Papillary Cell Carcinoma (TCGA): 6.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 10.1" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Alveolar cells type 1, Pancreas - Alpha cells, Pancreas - Beta cells, Prostate - Prostate glandular cells, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010056, HPA026685, HPA063573" Enhanced Supported Approved "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes No "Cluster 27: Cerebellum - Synaptic function" "Cluster 2: Neurons - Nucleosome" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 48 Microtubules "Cytokinetic bridge, Mitotic spindle" "CAB010056: , HPA026685: , HPA063573: " "unprognostic (8.86e-2)" "unprognostic (4.62e-2)" "unprognostic (2.35e-2)" "potential prognostic favorable (5.52e-5)" "unprognostic (2.67e-1)" "unprognostic (1.67e-2)" "unprognostic (3.23e-1)" "potential prognostic favorable (6.55e-6)" "unprognostic (9.44e-3)" "unprognostic (5.79e-2)" "unprognostic (7.03e-2)" "unprognostic (6.79e-2)" "unprognostic (8.39e-2)" "unprognostic (1.99e-2)" SH3GL3 "CNSA3, EEN-B2, HsT19371, SH3D2C, SH3P13" ENSG00000140600 "SH3 domain containing GRB2 like 3, endophilin A3" Q99963 15 83447228-83618743 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 56.9;testis: 24.8" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 268.4;Brain inhibitory neurons: 285.3;Early spermatids: 803.5;Ependymal cells: 205.6;Late primary spermatocytes: 249.4;Late spermatids: 2395.6;Loop of henle epithelial cells: 328.4;Oligodendrocytes: 1310.9;Retinal horizontal cells: 538.9" "Cell type enhanced" "Detected in all" "oligodendrocyte: 1662.2" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 3.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 14.0" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Lung - Alveolar cells type 1, Minor Salivary Gland - Minor salivary gland basal cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039381, HPA077877" Enhanced Approved Mitochondria NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 80: Oligodendrocytes - Myelination" 25 Mitochondria "HPA039381: , HPA077877: " "unprognostic (1.42e-2)" "unprognostic (5.94e-2)" "unprognostic (7.24e-3)" "unprognostic (2.47e-1)" "unprognostic (1.56e-1)" "unprognostic (1.48e-1)" "unprognostic (2.69e-1)" "unprognostic (1.24e-1)" "unprognostic (1.72e-1)" "unprognostic (4.14e-1)" SH3GLB1 "Bif-1, CGI-61, KIAA0491, PPP1R70" ENSG00000097033 "SH3 domain containing GRB2 like, endophilin B1" Q9Y371 1 86704570-86748184 "Metabolic proteins, Predicted intracellular proteins, Transporters" "Apoptosis, Autophagy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 578.0;Esophageal apical cells: 1111.7;Late primary spermatocytes: 954.3;Neutrophils: 1166.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 302.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004650, HPA015608, HPA019900" Enhanced Supported Cytosol NA NA 12000 "Cluster 35: Neutrophils - Protein binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 24: Neutrophils - Innate immunity signal integration" 129 Cytosol "CAB004650: , HPA015608: , HPA019900: " "unprognostic (4.31e-2)" "unprognostic (3.04e-1)" "unprognostic (2.99e-1)" "unprognostic (1.70e-2)" "unprognostic (2.90e-2)" "unprognostic (1.87e-1)" "unprognostic (2.45e-1)" "unprognostic (1.05e-2)" "unprognostic (1.88e-2)" "potential prognostic unfavorable (3.47e-4)" "validated prognostic favorable (1.54e-7)" "validated prognostic favorable (3.70e-5)" "unprognostic (6.18e-2)" "potential prognostic unfavorable (1.34e-6)" "unprognostic (5.10e-2)" "unprognostic (2.80e-2)" "unprognostic (5.92e-3)" "unprognostic (9.65e-2)" "unprognostic (1.71e-2)" "unprognostic (6.26e-2)" "unprognostic (9.85e-2)" "unprognostic (4.78e-3)" "unprognostic (1.40e-1)" "unprognostic (3.12e-1)" "unprognostic (2.57e-2)" "unprognostic (1.16e-1)" "unprognostic (2.46e-1)" "unprognostic (8.39e-2)" "unprognostic (2.47e-1)" "unprognostic (8.82e-2)" "unprognostic (1.08e-1)" SH3GLB2 KIAA1848 ENSG00000148341 "SH3 domain containing GRB2 like, endophilin B2" Q9NR46 9 129007036-129028331 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 156.1;Esophageal apical cells: 239.5;Syncytiotrophoblasts: 192.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Pituitary gland - Corticotropes, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021438, HPA024734" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 53: Neurons - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 30 Cytosol Nucleoplasm "HPA021438: , HPA024734: " "unprognostic (9.37e-2)" "unprognostic (3.86e-1)" "unprognostic (3.57e-1)" "unprognostic (1.49e-2)" "unprognostic (1.84e-1)" "unprognostic (5.51e-3)" "unprognostic (2.29e-1)" "unprognostic (7.31e-2)" "unprognostic (3.55e-1)" "unprognostic (2.33e-1)" "potential prognostic favorable (2.67e-5)" "unprognostic (2.77e-1)" "unprognostic (3.04e-3)" "unprognostic (3.01e-2)" "unprognostic (6.18e-2)" "unprognostic (4.39e-2)" "unprognostic (1.10e-1)" "unprognostic (4.73e-2)" "unprognostic (1.95e-1)" "unprognostic (8.59e-2)" "unprognostic (1.66e-1)" "unprognostic (2.58e-1)" "unprognostic (9.46e-2)" "unprognostic (1.03e-1)" "unprognostic (2.28e-1)" "unprognostic (8.06e-2)" "unprognostic (5.46e-1)" "unprognostic (1.27e-2)" "unprognostic (1.78e-2)" "unprognostic (2.63e-2)" "potential prognostic favorable (3.00e-4)" SH3KBP1 CIN85 ENSG00000147010 "SH3 domain containing kinase binding protein 1" Q96B97 X 19533977-19887600 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Endocytosis, Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Choroid plexus epithelial cells: 587.0;Microglia: 651.4;Monocyte progenitors: 490.2;Neutrophil progenitors: 864.8;Neutrophils: 1676.0;NK-cells: 448.6;pDCs: 455.7;T-cells: 465.8" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 832.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003351, HPA003355, CAB021892" Enhanced Supported Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 55: Lymphoma - Immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 127 Cytosol "CAB021892: , HPA003351: , HPA003355: " "unprognostic (3.08e-1)" "unprognostic (3.78e-2)" "unprognostic (8.59e-3)" "unprognostic (6.44e-3)" "unprognostic (4.85e-2)" "unprognostic (1.20e-1)" "unprognostic (1.17e-1)" "unprognostic (2.69e-2)" "unprognostic (8.76e-2)" "unprognostic (6.38e-2)" "unprognostic (3.99e-2)" "unprognostic (1.81e-2)" "unprognostic (5.94e-3)" "unprognostic (2.53e-2)" "unprognostic (4.27e-2)" "unprognostic (1.44e-2)" "unprognostic (1.91e-2)" "unprognostic (1.48e-1)" "unprognostic (1.03e-1)" "unprognostic (3.95e-3)" "unprognostic (3.40e-1)" "potential prognostic unfavorable (5.62e-4)" "unprognostic (7.20e-3)" "unprognostic (1.28e-1)" "unprognostic (2.19e-1)" "unprognostic (2.34e-1)" "unprognostic (7.28e-2)" "unprognostic (2.97e-1)" "unprognostic (1.49e-1)" "unprognostic (3.14e-3)" "unprognostic (2.57e-1)" SH3PXD2A "FISH, KIAA0418, SH3MD1" ENSG00000107957 "SH3 and PX domains 2A" Q5TCZ1 10 103594027-103855584 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 408.1;Esophageal apical cells: 751.7;Retinal horizontal cells: 354.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Liver - Hepatocytes, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037922, HPA037923" Approved Approved "Primary cilium transition zone,Cytosol" NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 6: Non-specific - Immune response" "Cluster 69: Skin cancer - ECM organization" "Cluster 103: Non-specific - Basic cellular processes" 25 "Primary cilium transition zone, Cytosol" "HPA037922: , HPA037923: " "unprognostic (1.47e-1)" "unprognostic (2.29e-1)" "unprognostic (2.10e-1)" "unprognostic (1.68e-2)" "unprognostic (7.48e-2)" "unprognostic (1.16e-1)" "unprognostic (3.35e-1)" "unprognostic (1.31e-1)" "unprognostic (1.61e-1)" "unprognostic (7.78e-2)" "unprognostic (2.99e-2)" "unprognostic (2.52e-2)" "unprognostic (6.33e-2)" "unprognostic (2.62e-2)" "unprognostic (1.10e-1)" "unprognostic (1.35e-1)" "unprognostic (1.57e-2)" "unprognostic (1.70e-1)" "unprognostic (9.72e-2)" "potential prognostic unfavorable (2.13e-4)" "unprognostic (1.23e-2)" "unprognostic (7.13e-2)" "unprognostic (3.84e-2)" "unprognostic (2.23e-1)" "unprognostic (1.72e-1)" "unprognostic (5.39e-2)" "unprognostic (2.10e-1)" "unprognostic (3.70e-1)" "unprognostic (3.11e-1)" "unprognostic (2.42e-2)" "unprognostic (2.81e-1)" SH3PXD2B "FLJ20831, KIAA1295" ENSG00000174705 "SH3 and PX domains 2B" A1X283 5 172325000-172454525 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Differentiation "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 309.2;Decidual stromal cells: 228.0;Fibro-adipogenic progenitors: 286.5;Fibroblasts: 261.4;Leydig cells: 320.4;Pituicytes/FSCs: 404.4" "Cell type enhanced" "Detected in all" "astrocyte: 243.2;ependymal cell: 170.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Pituitary gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036471, HPA058141" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 6: Non-specific - Immune response" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 103: Non-specific - Basic cellular processes" 12 "Plasma membrane" "Nucleoplasm, Cytosol" "HPA036471: , HPA058141: " "unprognostic (5.15e-1)" "unprognostic (1.82e-1)" "unprognostic (3.00e-1)" "unprognostic (1.82e-3)" "unprognostic (2.21e-1)" "unprognostic (8.87e-3)" "unprognostic (3.29e-1)" "unprognostic (1.51e-2)" "unprognostic (1.54e-1)" "unprognostic (2.05e-2)" "unprognostic (8.39e-2)" "unprognostic (5.23e-2)" "unprognostic (5.19e-2)" "potential prognostic unfavorable (2.31e-6)" "unprognostic (8.36e-2)" "unprognostic (3.98e-2)" "potential prognostic unfavorable (2.72e-4)" "unprognostic (9.47e-3)" "unprognostic (2.57e-1)" "unprognostic (7.87e-3)" "unprognostic (3.25e-3)" "unprognostic (3.04e-2)" "unprognostic (5.47e-3)" "unprognostic (5.55e-2)" "unprognostic (5.64e-2)" "unprognostic (5.04e-3)" "unprognostic (1.89e-1)" "unprognostic (2.32e-2)" "unprognostic (1.57e-1)" "unprognostic (1.65e-2)" "unprognostic (5.61e-2)" SH3RF1 "KIAA1494, POSH, RNF142, SH3MD2" ENSG00000154447 "SH3 domain containing ring finger 1" Q7Z6J0 4 169094259-169270956 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 607.0;Ocular epithelial cells: 684.8;Podocytes: 847.1;Renal connecting tubule cells: 654.9;Salivary acinar cells: 859.0;Urothelial cells: 623.1" "Cell type enhanced" "Detected in all" "pericyte: 748.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 4.2;myeloid DC: 2.5;non-classical monocyte: 6.8" "Group enriched" "Detected in many" 15 "dendritic cells: 2.5;monocytes: 6.8" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 1, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074783 Approved Supported "Vesicles,Intermediate filaments" No No "Cluster 40: Monocytes - Innate immune response" "Cluster 60: Stomach - Digestion" "Cluster 29: Forebrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 20 Vesicles "Intermediate filaments" "HPA074783: " "unprognostic (1.38e-1)" "unprognostic (6.51e-2)" "unprognostic (4.81e-3)" "unprognostic (9.59e-2)" "unprognostic (2.62e-2)" "unprognostic (2.62e-1)" "unprognostic (1.16e-1)" "unprognostic (1.37e-1)" "unprognostic (8.77e-3)" "unprognostic (3.30e-1)" "validated prognostic favorable (8.55e-8)" "validated prognostic favorable (2.03e-5)" "unprognostic (4.70e-2)" "unprognostic (8.69e-2)" "unprognostic (2.75e-3)" "unprognostic (4.07e-1)" "unprognostic (2.35e-2)" "unprognostic (8.39e-3)" "unprognostic (1.07e-1)" "unprognostic (4.77e-2)" "unprognostic (7.64e-2)" "unprognostic (1.25e-2)" "unprognostic (9.88e-2)" "unprognostic (1.11e-1)" "unprognostic (1.54e-1)" "unprognostic (2.61e-1)" "unprognostic (1.78e-1)" "unprognostic (4.69e-2)" "unprognostic (1.59e-1)" "unprognostic (1.91e-2)" "unprognostic (2.28e-1)" SH3RF2 "FLJ23654, Hepp1, POSHER, PPP1R39, RNF158" ENSG00000156463 "SH3 domain containing ring finger 2" Q8TEC5 5 145936578-146081791 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Protein phosphatase inhibitor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 54.7;skeletal muscle: 40.2;skin 1: 53.6" "Cell type enriched" "Detected in many" 6 "Late spermatids: 13187.8" "Cell type enriched" "Detected in many" 4 "medium spiny neuron: 183.1" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "basal ganglia: 14.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast myoepithelial cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary gland basal cells, Skin - Keratinocyte (other), Testis - Late spermatids" "Region enriched" "Detected in many" 14 "basal ganglia: 26.7" "Region enhanced" "Detected in many" "basal ganglia: 12.7" "HPA035903, HPA058119" Uncertain Enhanced Nucleoplasm NA Yes "Cluster 58: Skin - Keratinization" "Cluster 53: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 14 Nucleoplasm "HPA035903: , HPA058119: " "unprognostic (9.06e-2)" "unprognostic (1.15e-2)" "unprognostic (8.42e-2)" "unprognostic (7.67e-2)" "unprognostic (1.39e-1)" "unprognostic (4.04e-2)" "unprognostic (9.72e-3)" "unprognostic (2.20e-1)" "unprognostic (2.46e-2)" "unprognostic (2.12e-1)" "unprognostic (1.81e-1)" "unprognostic (1.28e-2)" "unprognostic (3.25e-2)" "unprognostic (1.33e-2)" "unprognostic (2.09e-2)" "unprognostic (1.46e-1)" "unprognostic (2.34e-1)" "unprognostic (2.29e-2)" "unprognostic (1.49e-1)" "unprognostic (1.17e-3)" "unprognostic (1.49e-1)" "unprognostic (9.77e-2)" "unprognostic (1.69e-3)" "unprognostic (3.99e-2)" "unprognostic (2.35e-1)" "unprognostic (9.16e-2)" "unprognostic (2.57e-1)" "unprognostic (6.75e-3)" "unprognostic (2.95e-2)" SH3RF3 "FLJ00204, POSH2, SH3MD4" ENSG00000172985 "SH3 domain containing ring finger 3" Q8TEJ3 2 109129205-109504634 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 200.0;Fibro-adipogenic progenitors: 198.7;Microglia: 627.5;Retinal horizontal cells: 166.3;Vascular endothelial cells: 221.4;Vascular smooth muscle cells: 287.4" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 834.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Prostate - Smooth muscle cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA044822, HPA048444" Approved Supported Nucleoplasm Yes No "Cluster 74: Non-specific - Signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 8 Nucleoplasm "HPA044822: , HPA048444: " "unprognostic (7.30e-2)" "unprognostic (3.30e-1)" "unprognostic (6.16e-2)" "unprognostic (2.43e-3)" "unprognostic (1.38e-1)" "unprognostic (1.50e-2)" "unprognostic (2.86e-1)" "unprognostic (6.27e-2)" "unprognostic (3.48e-1)" "potential prognostic favorable (9.85e-4)" "unprognostic (5.17e-2)" "unprognostic (6.52e-3)" "unprognostic (1.62e-1)" "unprognostic (2.66e-3)" "unprognostic (1.62e-1)" "unprognostic (6.54e-2)" "unprognostic (1.18e-1)" "unprognostic (1.18e-1)" "validated prognostic unfavorable (2.41e-4)" "validated prognostic unfavorable (5.33e-4)" "unprognostic (5.94e-2)" "unprognostic (8.78e-2)" "unprognostic (3.39e-1)" "unprognostic (2.25e-1)" "unprognostic (2.16e-3)" "unprognostic (2.25e-2)" "unprognostic (6.55e-2)" "unprognostic (1.20e-1)" "unprognostic (1.59e-2)" "unprognostic (1.16e-1)" SH3TC1 FLJ20356 ENSG00000125089 "SH3 domain and tetratricopeptide repeats 1" Q8TE82 4 8182072-8241803 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "lymphoid tissue: 90.3" "Cell type enhanced" "Detected in many" "cDC: 83.0;Esophageal apical cells: 150.4;Hofbauer cells: 75.7;Kupffer cells: 115.8;Macrophages: 109.0;Microglia: 112.2;monocytes: 95.2;Ocular epithelial cells: 75.5;pDCs: 98.2;Renal collecting duct intercalated cells: 120.3" "Cell type enriched" "Detected in some" 6 "central nervous system macrophage: 142.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 28.8" "Group enriched" "Detected in all" 5 "B-cells: 8.8;dendritic cells: 28.8;monocytes: 25.2" "Cancer enhanced" "Detected in many" "lymphoma: 52.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA038132, HPA056807" Uncertain Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 80: Thymus - Adaptive immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" "Nucleoli, Nucleoli rim" "Nucleoplasm, Cytosol" "HPA038132: , HPA056807: " "unprognostic (1.73e-1)" "unprognostic (1.81e-1)" "unprognostic (3.05e-2)" "unprognostic (2.43e-2)" "unprognostic (1.15e-1)" "unprognostic (1.42e-1)" "unprognostic (4.28e-3)" "unprognostic (7.85e-2)" "unprognostic (9.13e-2)" "unprognostic (2.86e-1)" "validated prognostic favorable (3.44e-5)" "validated prognostic favorable (8.72e-4)" "unprognostic (3.10e-2)" "unprognostic (1.44e-2)" "unprognostic (1.12e-1)" "unprognostic (2.15e-1)" "unprognostic (1.08e-1)" "unprognostic (6.16e-3)" "unprognostic (5.78e-2)" "unprognostic (2.21e-1)" "unprognostic (1.20e-1)" "unprognostic (1.86e-2)" "potential prognostic unfavorable (1.64e-5)" "unprognostic (1.17e-1)" "unprognostic (1.22e-2)" "unprognostic (2.31e-2)" "unprognostic (9.90e-2)" "unprognostic (2.79e-1)" "unprognostic (2.68e-2)" "unprognostic (2.17e-2)" "unprognostic (2.39e-1)" SH3TC2 "CMT4C, KIAA1985" ENSG00000169247 "SH3 domain and tetratricopeptide repeats 2" Q8TF17 5 148923639-149063163 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 4.5;retina: 3.6;testis: 1.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 53.4;Esophageal apical cells: 70.4;Oligodendrocytes: 286.3;Platelets: 91.7;Rod photoreceptor cells: 192.9;Sertoli cells: 156.6;Syncytiotrophoblasts: 75.9;Tuft cells: 46.1" "Group enriched" "Detected in many" 8 "committed oligodendrocyte precursor: 104.4;oligodendrocyte: 386.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 4.4;skin cancer: 4.9" "Breast - Breast myoepithelial cells, Skin - Sebaceous gland cells, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA037683, HPA037684" Uncertain Approved Nucleoplasm,Cytosol No No "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 79: Photoreceptor cells - Phototransduction" "Nucleoplasm, Cytosol" "HPA037683: , HPA037684: " "unprognostic (2.33e-1)" "unprognostic (5.99e-2)" "unprognostic (6.00e-2)" "unprognostic (5.83e-2)" "unprognostic (5.49e-2)" SH3YL1 "DKFZP586F1318, Ray" ENSG00000035115 "SH3 and SYLF domain containing 1" Q96HL8 2 217730-266398 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cholangiocytes: 437.9;Esophageal apical cells: 542.4;Parietal cells: 512.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Skeletal muscle - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030926, HPA030927" Enhanced Approved Nucleoplasm NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 8: Pancreas - Proteolysis" "Cluster 30: White matter - Myelination" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 11 Nucleoplasm "HPA030926: , HPA030927: " "unprognostic (8.91e-3)" "unprognostic (9.30e-2)" "unprognostic (1.57e-2)" "unprognostic (5.60e-2)" "unprognostic (5.08e-2)" "unprognostic (2.67e-2)" "unprognostic (4.30e-2)" "unprognostic (9.40e-3)" "unprognostic (2.00e-1)" "unprognostic (8.87e-2)" "validated prognostic favorable (1.03e-9)" "validated prognostic favorable (7.11e-4)" "unprognostic (3.08e-2)" "unprognostic (2.32e-1)" "unprognostic (2.40e-3)" "unprognostic (5.26e-2)" "unprognostic (8.30e-2)" "unprognostic (1.96e-2)" "unprognostic (2.04e-3)" "unprognostic (1.56e-1)" "unprognostic (2.30e-1)" "unprognostic (5.64e-2)" "unprognostic (9.40e-2)" "unprognostic (1.27e-1)" "unprognostic (3.69e-3)" "unprognostic (1.20e-1)" "unprognostic (3.09e-3)" "unprognostic (2.28e-3)" "unprognostic (1.72e-1)" "unprognostic (1.31e-1)" "unprognostic (1.41e-3)" SHANK1 "SPANK-1, SSTRIP, synamon" ENSG00000161681 "SH3 and multiple ankyrin repeat domains 1" Q9Y566 19 50659255-50719802 "Plasma proteins, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "brain: 60.6" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 42.5;Brain excitatory neurons: 40.3;Brain inhibitory neurons: 32.8;Epididymal efferent duct absorptive cells: 53.4;Innate lymphoid cells: 34.1;Lactotrophs: 44.4;Other brain neurons: 31.7;Retinal amacrine cells: 108.1;Retinal bipolar cells: 74.9;Retinal ganglion cells: 38.6;Retinal horizontal cells: 122.2;Somatotrophs: 28.9" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 2.7;Ovary Serous Cystadenocarcinoma (TCGA): 3.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 6.4;Neuroblastoma: 8.3" "Adipose visceral - Adipose progenitor cells, Colon - Enteric glia cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032129, HPA032130" Uncertain Supported "Plasma membrane" NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" 11 "Plasma membrane" "HPA032129: , HPA032130: " "unprognostic (2.19e-1)" "unprognostic (3.74e-2)" "unprognostic (6.16e-2)" "unprognostic (8.57e-2)" "unprognostic (2.22e-2)" SHANK2 "CORTBP1, CTTNBP1, ProSAP1, SHANK, SPANK-3" ENSG00000162105 "SH3 and multiple ankyrin repeat domains 2" Q9UPX8 11 70467854-71252577 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 9.8" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 1257.3;Ependymal cells: 597.4;Proximal tubule cells: 563.9;Renal collecting duct intercalated cells: 600.1;Renal connecting tubule cells: 517.9;Respiratory ciliated cells: 647.7;Retinal horizontal cells: 1059.8;Retinal pigment epithelial cells: 541.4;Salivary acinar cells: 523.7" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 1205.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008174, HPA017220" Approved Approved "Nucleoplasm,Nuclear speckles,Vesicles,Plasma membrane" NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" 7 "Nuclear speckles, Vesicles" "Nucleoplasm, Plasma membrane" "HPA008174: , HPA017220: " "unprognostic (1.11e-1)" "unprognostic (2.54e-1)" "unprognostic (4.04e-1)" "potential prognostic unfavorable (4.85e-5)" "unprognostic (1.09e-1)" "unprognostic (8.24e-2)" "unprognostic (2.92e-1)" "unprognostic (5.01e-2)" "unprognostic (1.29e-3)" "unprognostic (1.91e-1)" "potential prognostic favorable (1.10e-7)" "unprognostic (7.48e-2)" "unprognostic (9.46e-2)" "unprognostic (2.46e-1)" "potential prognostic favorable (2.44e-4)" "unprognostic (3.12e-1)" "unprognostic (2.47e-1)" "unprognostic (2.79e-3)" "unprognostic (5.98e-1)" "unprognostic (2.00e-1)" "unprognostic (1.30e-2)" "unprognostic (8.94e-3)" "unprognostic (4.51e-2)" "unprognostic (3.14e-1)" "unprognostic (2.89e-2)" "unprognostic (5.55e-2)" "unprognostic (6.22e-2)" "unprognostic (1.97e-3)" "unprognostic (3.69e-2)" "unprognostic (1.58e-1)" SHANK3 "KIAA1650, prosap2, PSAP2, SPANK-2" ENSG00000251322 "SH3 and multiple ankyrin repeat domains 3" 22 50674415-50733212 "Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 155.9;lymphoid tissue: 119.5" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 69.9;Brain inhibitory neurons: 40.6;Ependymal cells: 40.9;Lymphatic endothelial cells: 25.1;Oligodendrocyte progenitor cells: 39.9;Oligodendrocytes: 60.0;Other brain neurons: 21.1;Proximal tubule cells: 36.2;Vascular endothelial cells: 45.5" "Cell type enhanced" "Detected in all" "endothelial cell: 303.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Spleen - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" HPA003446 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 5: Spleen - Immune response" "Cluster 51: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 28 "Nucleoplasm, Plasma membrane" "HPA003446: " "unprognostic (1.55e-2)" "unprognostic (2.38e-1)" "unprognostic (1.02e-2)" "unprognostic (2.13e-2)" "potential prognostic unfavorable (2.52e-4)" "unprognostic (2.61e-1)" "unprognostic (4.32e-1)" "unprognostic (2.46e-2)" "unprognostic (1.56e-2)" "unprognostic (4.14e-3)" "unprognostic (1.79e-3)" "potential prognostic favorable (9.66e-4)" "unprognostic (9.72e-2)" "unprognostic (2.69e-2)" "unprognostic (1.35e-2)" "unprognostic (1.35e-1)" "unprognostic (1.80e-1)" "unprognostic (9.68e-2)" "unprognostic (8.70e-2)" "unprognostic (1.49e-1)" "unprognostic (3.25e-3)" "unprognostic (3.25e-3)" "unprognostic (1.29e-2)" "unprognostic (1.36e-1)" "unprognostic (2.55e-1)" "unprognostic (2.07e-2)" "unprognostic (1.32e-1)" "unprognostic (1.14e-1)" "unprognostic (2.29e-1)" "unprognostic (5.23e-2)" "unprognostic (1.30e-1)" SHARPIN "DKFZP434N1923, SIPL1" ENSG00000179526 "SHANK associated RH domain interactor" Q9H0F6 8 144098633-144108124 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Late spermatids: 2267.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024825, HPA044453" Approved Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 19: Astrocytes - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 55 "Plasma membrane" "Golgi apparatus, Cytosol" "HPA024825: , HPA044453: " "unprognostic (1.07e-1)" "potential prognostic unfavorable (9.31e-4)" "unprognostic (2.45e-1)" "unprognostic (4.83e-2)" "unprognostic (3.38e-2)" "unprognostic (4.45e-2)" "unprognostic (6.90e-2)" "unprognostic (4.77e-2)" "unprognostic (1.91e-2)" "unprognostic (6.84e-2)" "potential prognostic unfavorable (4.91e-5)" "unprognostic (4.87e-3)" "unprognostic (1.47e-1)" "unprognostic (3.52e-3)" "unprognostic (1.85e-2)" "unprognostic (7.83e-2)" "unprognostic (5.36e-2)" "unprognostic (4.73e-2)" "unprognostic (2.31e-1)" "unprognostic (3.41e-2)" "unprognostic (2.18e-2)" "unprognostic (2.19e-2)" "unprognostic (2.33e-2)" "unprognostic (8.00e-2)" "unprognostic (4.77e-2)" "unprognostic (6.66e-2)" "unprognostic (3.45e-1)" "unprognostic (7.07e-2)" "unprognostic (6.28e-2)" "unprognostic (6.52e-2)" "unprognostic (2.25e-1)" SHB ENSG00000107338 "SH2 domain containing adaptor protein B" Q15464 9 37915898-38069227 "Predicted intracellular proteins" "Angiogenesis, Apoptosis, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 22.3;Brain inhibitory neurons: 19.4;Choroid plexus epithelial cells: 62.4;Oligodendrocyte progenitor cells: 19.0;Oligodendrocytes: 78.9;Other brain neurons: 14.0;Tuft cells: 23.1" "Cell type enhanced" "Detected in many" "endothelial cell: 118.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 22 "basophil: 2.2" "Lineage enriched" "Detected in single" 22 "granulocytes: 2.2" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010161, HPA049911, HPA052108" Uncertain Supported "Nucleoplasm,Cytosol,Cytoplasmic bodies" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 70: Non-specific - Protein processing" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 104: Brain endothelial cells - Blood brain barrier" 13 Cytosol "Nucleoplasm, Cytoplasmic bodies" "CAB010161: , HPA049911: , HPA052108: " "unprognostic (9.76e-2)" "unprognostic (1.31e-1)" "unprognostic (4.52e-1)" "unprognostic (7.63e-2)" "unprognostic (1.93e-1)" "unprognostic (1.96e-3)" "unprognostic (2.82e-1)" "potential prognostic favorable (7.84e-4)" "unprognostic (3.55e-2)" "unprognostic (3.94e-2)" "unprognostic (9.62e-3)" "unprognostic (1.39e-1)" "potential prognostic favorable (5.20e-4)" "unprognostic (8.51e-2)" "potential prognostic favorable (5.08e-5)" "unprognostic (2.37e-1)" "unprognostic (1.81e-3)" "unprognostic (1.66e-1)" "unprognostic (7.27e-2)" "unprognostic (1.48e-1)" "unprognostic (4.01e-2)" "unprognostic (1.01e-2)" "unprognostic (1.62e-1)" "unprognostic (7.72e-2)" "unprognostic (1.48e-1)" "unprognostic (1.85e-1)" "unprognostic (1.72e-1)" "unprognostic (1.05e-1)" "unprognostic (2.28e-1)" "unprognostic (9.80e-2)" "unprognostic (4.84e-2)" SHBG "ABP, MGC126834, MGC138391, TEBG" ENSG00000129214 "Sex hormone binding globulin" P04278 17 7613946-7633382 "Cancer-related genes, Candidate cardiovascular disease genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 59.3" "Group enriched" "Detected in many" 5 "Cardiomyocytes: 782.6;Epicardial cells: 234.2;Late spermatids: 201.6" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in some" 16 "Liver Hepatocellular Carcinoma (TCGA): 29.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Testis - Late spermatids" "Not detected" "Not detected" "Secreted to blood" Transport NA NA 2700000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 39: Astrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" "unprognostic (7.32e-2)" "unprognostic (2.94e-2)" "unprognostic (5.73e-2)" "unprognostic (4.41e-2)" "unprognostic (2.36e-1)" "unprognostic (2.20e-2)" "unprognostic (3.24e-2)" "unprognostic (2.77e-1)" SHC1 "p66, SHC, ShcA" ENSG00000160691 "SHC adaptor protein 1" P29353 1 154962298-154974395 "Predicted intracellular proteins, RAS pathway related proteins" "Angiogenesis, Growth regulation, Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 18.3;Enterocytes: 18.6;Epicardial cells: 20.5;Lymphatic endothelial cells: 20.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001844, CAB005374, CAB016305" Supported Enhanced Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 19: Astrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 118 Cytosol "CAB005374: , CAB016305: , HPA001844: " "unprognostic (6.26e-2)" "unprognostic (2.06e-1)" "unprognostic (3.84e-1)" "potential prognostic unfavorable (2.78e-4)" "unprognostic (5.64e-2)" "unprognostic (9.76e-2)" "unprognostic (5.96e-2)" "unprognostic (5.73e-2)" "unprognostic (2.34e-2)" "unprognostic (7.96e-3)" "unprognostic (1.38e-1)" "potential prognostic unfavorable (3.15e-4)" "potential prognostic unfavorable (4.07e-5)" "unprognostic (2.91e-3)" "unprognostic (1.53e-3)" "potential prognostic unfavorable (6.14e-5)" "unprognostic (2.37e-2)" "unprognostic (2.22e-2)" "unprognostic (1.05e-1)" "unprognostic (1.25e-1)" "unprognostic (1.21e-1)" "unprognostic (2.40e-2)" "unprognostic (5.07e-3)" "unprognostic (5.41e-2)" "potential prognostic unfavorable (4.00e-4)" "unprognostic (1.67e-2)" "unprognostic (3.23e-1)" "unprognostic (2.40e-1)" "unprognostic (2.33e-1)" "unprognostic (7.44e-2)" "unprognostic (4.70e-1)" SHC2 "SCK, SHCB, SLI" ENSG00000129946 "SHC adaptor protein 2" P98077 19 416589-461033 "Predicted intracellular proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 100.4" "Cell type enhanced" "Detected in many" "Astrocytes: 49.0;Hepatocytes: 66.5;Lymphatic endothelial cells: 55.2;Oligodendrocyte progenitor cells: 77.0;Pancreatic acinar cells: 118.7;Salivary acinar cells: 49.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 12.1" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells" HPA006136 Approved Approved Cytosol NA NA "Cluster 70: Non-specific - Protein processing" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 21 Cytosol "HPA006136: " "unprognostic (3.63e-2)" "unprognostic (2.33e-3)" "unprognostic (5.88e-2)" "unprognostic (7.32e-2)" "unprognostic (2.87e-2)" "unprognostic (4.81e-2)" "unprognostic (3.17e-1)" "unprognostic (2.05e-1)" "unprognostic (1.33e-1)" "unprognostic (4.37e-3)" "unprognostic (1.41e-2)" "unprognostic (1.01e-1)" "unprognostic (1.11e-2)" "unprognostic (1.28e-1)" "unprognostic (1.06e-2)" "unprognostic (2.07e-1)" "unprognostic (1.94e-1)" "unprognostic (3.77e-2)" "unprognostic (1.33e-1)" "unprognostic (1.42e-1)" "unprognostic (2.62e-1)" "unprognostic (1.43e-3)" "unprognostic (1.01e-1)" "unprognostic (1.16e-1)" "unprognostic (1.94e-2)" "unprognostic (9.11e-2)" "unprognostic (6.52e-2)" "unprognostic (1.08e-2)" "unprognostic (2.93e-1)" "unprognostic (1.57e-2)" "unprognostic (2.09e-1)" SHC3 "N-Shc, NSHC, SHCC" ENSG00000148082 "SHC adaptor protein 3" Q92529 9 89005771-89178818 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 39.5" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 433.3;Alveolar cells type 2: 92.5;Brain excitatory neurons: 112.7;Brain inhibitory neurons: 134.0;Distal convoluted tubule cells: 113.9;Oligodendrocyte progenitor cells: 474.2;Pituicytes/FSCs: 66.2" "Cell type enhanced" "Detected in all" "oligodendrocyte precursor cell: 530.8" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 8.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 10.6" "Breast - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031427, HPA046656, HPA072448" Uncertain Supported Nucleoplasm NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 35: Neurons - Synaptic function & neurogenesis" 38 Nucleoplasm "HPA031427: , HPA046656: , HPA072448: " "unprognostic (3.02e-2)" "unprognostic (2.79e-1)" "unprognostic (5.85e-2)" "unprognostic (1.48e-1)" "unprognostic (2.06e-1)" "unprognostic (1.15e-1)" "unprognostic (2.31e-1)" "unprognostic (8.10e-2)" "unprognostic (1.04e-2)" "unprognostic (1.25e-2)" "unprognostic (3.15e-1)" "unprognostic (1.78e-3)" "unprognostic (7.41e-3)" "unprognostic (4.01e-2)" "unprognostic (3.72e-2)" SHC4 "RaLP, SHCD" ENSG00000185634 "SHC adaptor protein 4" Q6S5L8 15 48823741-48963919 "Predicted intracellular proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 8.0;brain: 14.7;testis: 9.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 254.6;Epicardial cells: 84.1;Oligodendrocyte progenitor cells: 54.5;Oligodendrocytes: 80.0;Schwann cells: 373.2;Sertoli cells: 243.0" "Cell type enhanced" "Detected in many" "oligodendrocyte: 99.7;oligodendrocyte precursor cell: 65.6" "Cancer enhanced" "Detected in some" "Skin Cutaneous Melanoma (TCGA): 18.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Brain cancer: 5.9;Sarcoma: 11.0;skin cancer: 17.2" "Adipose subcutaneous - Smooth muscle cells, Colon - Enteric glia cells, Minor Salivary Gland - Smooth muscle cells, Skin - Eccrine sweat gland cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074146 Approved Cytosol NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 54: Non-specific - Transcription" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 6 Cytosol "HPA074146: " "unprognostic (2.70e-2)" "unprognostic (3.69e-2)" "unprognostic (1.07e-2)" "unprognostic (2.44e-1)" "unprognostic (2.97e-1)" "unprognostic (3.77e-3)" "unprognostic (5.61e-2)" "unprognostic (6.02e-3)" "unprognostic (1.56e-1)" SHCBP1 "FLJ22009, PAL" ENSG00000171241 "SHC binding and spindle associated 1" Q8NEM2 16 46578591-46621379 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 16.4;lymphoid tissue: 9.9" "Cell type enhanced" "Detected in many" "Bergmann glia: 51.2;Differentiating spermatogonia: 30.4;Early primary spermatocytes: 42.9;Erythrocyte progenitors: 93.3;Extravillous trophoblasts: 43.3;Megakaryocyte progenitors: 54.1;Monocyte progenitors: 127.1;Neutrophil progenitors: 95.1;Plasma cells: 49.2;Renal connecting tubule cells: 32.9" "Cell type enhanced" "Detected in many" "Bergmann glia: 55.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Kidney - Ascending Loop of Henle cells, Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA048876 Uncertain Approved "Nuclear bodies,Microtubules,Midbody,Mitotic spindle" Yes Yes "Cluster 23: B-cells - Immunoglobulins" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 48: Non-specific - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 27: Non-specific - Cell proliferation" 27 "Nuclear bodies" "Microtubules, Midbody, Mitotic spindle" "HPA048876: " "unprognostic (1.16e-2)" "potential prognostic unfavorable (3.59e-4)" "unprognostic (3.38e-1)" "unprognostic (1.18e-1)" "unprognostic (1.36e-1)" "unprognostic (1.04e-1)" "unprognostic (2.16e-1)" "unprognostic (1.93e-1)" "unprognostic (6.29e-2)" "unprognostic (6.22e-3)" "validated prognostic unfavorable (1.94e-6)" "validated prognostic unfavorable (2.85e-6)" "potential prognostic unfavorable (2.94e-11)" "validated prognostic unfavorable (1.84e-4)" "validated prognostic unfavorable (5.01e-8)" "potential prognostic unfavorable (9.92e-7)" "unprognostic (1.34e-3)" "unprognostic (2.39e-1)" "unprognostic (1.25e-2)" "unprognostic (3.95e-1)" "unprognostic (3.90e-2)" "validated prognostic unfavorable (1.43e-7)" "validated prognostic unfavorable (5.21e-5)" "unprognostic (2.52e-3)" "unprognostic (8.34e-2)" "unprognostic (3.64e-2)" "unprognostic (3.24e-1)" "unprognostic (2.60e-1)" "unprognostic (3.26e-2)" SHCBP1L C1orf14 ENSG00000157060 "SHC binding and spindle associated 1 like" Q9BZQ2 1 182899865-182953525 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1072 "testis: 107.2" "Group enriched" "Detected in some" 13 "Early primary spermatocytes: 510.7;Early spermatids: 653.8;Late primary spermatocytes: 1240.4" "Low cell type specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA036124, HPA036125, HPA064821" Enhanced NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 4: Non-specific - Transcription" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 4 "HPA036124: , HPA036125: , HPA064821: " SHD ENSG00000105251 "Src homology 2 domain containing transforming protein D" Q96IW2 19 4279266-4290722 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 12.7;heart muscle: 21.3" "Cell type enriched" "Detected in some" 7 "Oocytes: 925.6" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 16.1;committed oligodendrocyte precursor: 27.8;oligodendrocyte precursor cell: 19.3" "Cancer enriched" "Detected in some" 7 "Glioblastoma Multiforme (TCGA): 27.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 179 "plasmacytoid DC: 17.8" "Lineage enriched" "Detected in single" 179 "dendritic cells: 17.8" "Cancer enriched" "Detected in some" 7 "Neuroblastoma: 113.3" "Colon - Colon enterocytes, Liver - Hepatocytes, Pituitary gland - Thyrotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017955 Uncertain Uncertain "Centriolar satellite,Cytosol" NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 35: Non-specific - Mixed function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 41: Oocytes - Oogenesis" 4 "Centriolar satellite, Cytosol" "HPA017955: " "unprognostic (1.14e-1)" "potential prognostic favorable (8.58e-4)" "unprognostic (3.65e-3)" "unprognostic (4.97e-2)" "unprognostic (2.34e-1)" "unprognostic (1.41e-2)" SHE ENSG00000169291 "Src homology 2 domain containing E" Q5VZ18 1 154469772-154502412 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 24.3;Alveolar cells type 2: 24.3;Differentiating spermatogonia: 24.2;Early primary spermatocytes: 28.4;Epicardial cells: 40.9;Kupffer cells: 74.8;Late primary spermatocytes: 33.3;Late spermatids: 34.9;Lymphatic endothelial cells: 94.6;Sertoli cells: 52.7;Thymic myoid cells: 36.7;Undifferentiated spermatogonia: 26.8;Vascular endothelial cells: 115.5" "Cell type enriched" "Detected in some" 9 "endothelial cell: 159.1" "Cancer enhanced" "Detected in all" "Thyroid Carcinoma (TCGA): 26.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Minor Salivary Gland - Endothelial cells, Pancreas - Endothelial cells, Pituitary gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Spleen - Endothelial cells, Stomach - Endothelial cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037417 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 11: Neuronal - Sensory perception" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 1 Nucleoplasm Cytosol "HPA037417: " "unprognostic (1.31e-1)" "unprognostic (1.25e-1)" "unprognostic (2.86e-2)" "potential prognostic favorable (1.44e-4)" "unprognostic (3.95e-1)" "unprognostic (8.58e-2)" "unprognostic (3.30e-1)" "unprognostic (2.69e-2)" "unprognostic (7.61e-3)" "unprognostic (3.69e-2)" "potential prognostic favorable (2.87e-8)" "unprognostic (1.49e-3)" "unprognostic (2.50e-1)" "unprognostic (1.26e-1)" "potential prognostic favorable (3.20e-5)" "unprognostic (4.55e-3)" "unprognostic (2.75e-1)" "unprognostic (3.05e-2)" "unprognostic (7.52e-2)" "unprognostic (6.28e-2)" "unprognostic (5.82e-2)" "unprognostic (1.59e-1)" "unprognostic (2.91e-2)" "unprognostic (1.48e-2)" "unprognostic (8.40e-2)" "unprognostic (4.94e-2)" "unprognostic (3.26e-2)" "unprognostic (1.41e-1)" "unprognostic (2.77e-3)" "unprognostic (8.63e-2)" SHF ENSG00000138606 "Src homology 2 domain containing F" Q7M4L6 15 45167214-45201175 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 61.4" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 42.5;Brain excitatory neurons: 40.5;Retinal bipolar cells: 43.4" "Cell type enhanced" "Detected in all" "upper rhombic lip: 79.5" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "cerebellum: 282.3" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Neuroblastoma: 43.8" "Adrenal gland - Adrenal cortex cells, Kidney - Fibroblasts, Prostate - Fibroblasts, Skin - Outer root sheath cells" "Region enriched" "Detected in all" 5 "cerebellum: 240.6" "Region enriched" "Detected in all" 4 "cerebellum: 165.5" HPA057381 Approved Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 64: Non-specific - Transcription" "Cluster 35: Non-specific - DNA binding" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 2: Cerebellar granular cells - Neuronal signaling" Nucleoplasm "HPA057381: " "unprognostic (4.06e-2)" "unprognostic (1.44e-1)" "unprognostic (1.29e-2)" "potential prognostic unfavorable (1.53e-6)" "unprognostic (3.87e-2)" "unprognostic (1.07e-1)" "unprognostic (2.17e-2)" "unprognostic (1.06e-3)" "unprognostic (8.74e-2)" "unprognostic (3.18e-1)" "unprognostic (1.32e-2)" "unprognostic (1.17e-1)" "unprognostic (4.68e-2)" "unprognostic (1.07e-1)" "unprognostic (6.03e-2)" "unprognostic (3.21e-2)" "unprognostic (2.75e-2)" "unprognostic (1.77e-1)" "unprognostic (1.83e-1)" "unprognostic (9.13e-3)" "unprognostic (3.52e-3)" "unprognostic (3.12e-1)" "unprognostic (2.57e-1)" "unprognostic (2.15e-1)" "unprognostic (1.60e-2)" "unprognostic (5.54e-2)" "unprognostic (8.67e-2)" "unprognostic (2.52e-2)" "unprognostic (8.49e-2)" "unprognostic (2.01e-2)" "unprognostic (5.71e-2)" SHFL "C19orf66, FLJ11286, IRAV, RyDEN, SFL" ENSG00000130813 "Shiftless antiviral inhibitor of ribosomal frameshifting" Q9NUL5 19 10086122-10093252 "Predicted intracellular proteins" "Antiviral defense" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 100.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 101.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042001 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 28 Nucleoplasm Cytosol "HPA042001: " "potential prognostic favorable (1.98e-4)" "unprognostic (1.82e-3)" "unprognostic (1.59e-1)" "unprognostic (2.34e-1)" "unprognostic (1.47e-1)" "unprognostic (3.04e-2)" "potential prognostic unfavorable (9.69e-5)" "unprognostic (2.68e-1)" "unprognostic (3.43e-2)" "unprognostic (8.02e-2)" "unprognostic (2.85e-1)" "unprognostic (8.13e-3)" "unprognostic (1.50e-1)" "unprognostic (1.71e-1)" "unprognostic (4.18e-1)" "unprognostic (3.11e-1)" "unprognostic (3.05e-1)" "unprognostic (1.26e-1)" "unprognostic (2.23e-1)" "unprognostic (5.55e-3)" "unprognostic (1.75e-2)" "unprognostic (1.25e-1)" "unprognostic (1.78e-1)" "unprognostic (2.36e-2)" "unprognostic (8.05e-2)" "unprognostic (1.27e-1)" "unprognostic (1.69e-1)" "unprognostic (1.85e-2)" "unprognostic (3.66e-2)" SHH "HHG1, HLP3, HPE3, MCOPCB5, SMMCI, TPT, TPTPS" ENSG00000164690 "Sonic hedgehog signaling molecule" Q15465 7 155799980-155812463 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein, Hydrolase, Protease, Transferase" "Disease variant, Holoprosencephaly, Microphthalmia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 8.2;liver: 12.5;stomach 1: 9.9;urinary bladder: 15.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 16.2;Basal prostatic cells: 18.0;Cholangiocytes: 14.6;Endometrial secretory cells: 16.2;Epididymal efferent duct absorptive cells: 21.4;Foveolar cells: 41.6;Hepatocytes: 25.0;Papillary tip epithelial cells: 25.7;Prostatic hillock cells: 46.6;Urothelial cells: 59.1" "Cell type enriched" "Detected in many" 4 "mammillary body: 31.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 13.5" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Pituitary gland - Gonadotropes, Skin - Inner root sheath cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Intracellular and membrane" "Developmental protein" NA NA 760000 "Cluster 76: Non-specific - Metabolism" "Cluster 45: Non-specific - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 69: Urothelial cells - Basic cellular functions" 2 "unprognostic (2.46e-2)" "unprognostic (1.05e-3)" "unprognostic (1.11e-1)" "unprognostic (9.09e-2)" "unprognostic (8.18e-2)" "unprognostic (1.99e-1)" "unprognostic (1.24e-1)" "unprognostic (4.61e-2)" "unprognostic (3.62e-2)" "unprognostic (1.69e-2)" "potential prognostic favorable (4.89e-4)" "unprognostic (9.52e-2)" "unprognostic (1.73e-1)" "unprognostic (1.86e-1)" "unprognostic (1.96e-1)" "unprognostic (2.70e-1)" "unprognostic (1.40e-2)" "unprognostic (7.36e-2)" "unprognostic (5.04e-3)" "unprognostic (2.68e-2)" "unprognostic (1.28e-1)" "unprognostic (5.04e-1)" "unprognostic (6.31e-3)" SHISA2 "bA398O19.2, C13orf13, hShisa, PRO28631, TMEM46, WGAR9166" ENSG00000180730 "Shisa family member 2" Q6UWI4 13 26044597-26052016 "Predicted membrane proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 11.7;skeletal muscle: 13.3;thyroid gland: 19.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 23.7;Breast hormone-responsive cells: 42.2;Breast secretory cells: 16.7;Conjunctival goblet cells: 31.1;Endometrial secretory cells: 22.7;Epididymal clear cells: 34.7;Epididymal principal cells: 19.4;Medullary thymic epithelial cells: 43.2;Respiratory ionocytes: 58.4;Respiratory secretory cells: 25.8;Retinal pigment epithelial cells: 25.6" "Cell type enhanced" "Detected in some" "committed oligodendrocyte precursor: 9.1;hippocampal CA1-3: 4.9" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 29.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Kidney cancer: 20.8" "Kidney - Podocytes, Lung - Alveolar cells type 2, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA049752, HPA050172" Uncertain Approved "Nucleoplasm,Nuclear bodies,Vesicles" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 33: Thyroid gland - Tissue development" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 6 Nucleoplasm "Nuclear bodies, Vesicles" "HPA049752: , HPA050172: " "unprognostic (5.17e-2)" "unprognostic (3.45e-2)" "unprognostic (3.74e-1)" "unprognostic (2.61e-2)" "unprognostic (2.43e-1)" "unprognostic (2.58e-1)" "unprognostic (6.54e-3)" "unprognostic (1.68e-1)" "unprognostic (1.12e-1)" "unprognostic (8.26e-3)" "potential prognostic favorable (1.74e-4)" "unprognostic (4.59e-2)" "unprognostic (1.02e-2)" "unprognostic (6.85e-2)" "unprognostic (2.22e-1)" "potential prognostic unfavorable (6.84e-5)" "unprognostic (3.61e-2)" "unprognostic (2.84e-2)" "unprognostic (3.31e-2)" "unprognostic (2.13e-1)" "unprognostic (1.99e-1)" "unprognostic (2.61e-1)" "unprognostic (8.20e-3)" "unprognostic (9.78e-2)" "unprognostic (2.61e-1)" "unprognostic (5.50e-3)" SHISA3 hShisa3 ENSG00000178343 "Shisa family member 3" A0PJX4 4 42397488-42402487 "Predicted membrane proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 13.5;kidney: 19.3" "Cell type enhanced" "Detected in some" "Decidual stromal cells: 23.2;Distal convoluted tubule cells: 14.7;Epididymal efferent duct absorptive cells: 88.1;Fibroblasts: 15.1;Loop of henle epithelial cells: 12.8;Podocytes: 17.6" "Group enriched" "Detected in some" 5 "choroid plexus epithelial cell: 3.0;endothelial cell: 7.8" "Group enriched" "Detected in many" 5 "Kidney Chromophobe (TCGA): 16.3;Kidney Renal Clear Cell Carcinoma (TCGA): 8.5;Kidney Renal Papillary Cell Carcinoma (TCGA): 14.3;Lung Adenocarcinoma (TCGA): 17.2" "Group enriched" "Detected in all" 5 "midbrain: 29.0;thalamus: 19.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder cancer: 18.1;Neuroblastoma: 17.8;Sarcoma: 19.7" "Breast - Endothelial cells, Liver - Hepatic stellate cells, Stomach - Fibroblasts" "Region enriched" "Detected in many" 23 "olfactory bulb: 51.7" "Region enriched" "Detected in all" 5 "spinal cord: 30.5" HPA054754 Approved "Lipid droplets,Cytosol" NA Yes "Cluster 72: Kidney - Transmembrane transport" "Cluster 19: Astrocytes - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 108: Fibroblasts - ECM organization" 17 Cytosol "Lipid droplets" "HPA054754: " "unprognostic (6.66e-3)" "unprognostic (3.06e-3)" "unprognostic (4.77e-2)" "unprognostic (1.67e-1)" "unprognostic (3.17e-2)" "unprognostic (2.52e-1)" "unprognostic (7.53e-3)" "unprognostic (4.18e-2)" "unprognostic (1.41e-1)" "potential prognostic favorable (2.08e-5)" "unprognostic (2.08e-1)" "unprognostic (1.93e-2)" "unprognostic (2.66e-2)" "unprognostic (1.52e-1)" "unprognostic (4.51e-3)" "unprognostic (5.96e-1)" "unprognostic (1.66e-1)" "unprognostic (4.81e-2)" "unprognostic (2.76e-2)" "unprognostic (7.42e-2)" "unprognostic (1.78e-1)" SHISA4 "C1orf40, hShisa4, TMEM58" ENSG00000198892 "Shisa family member 4" Q96DD7 1 201888680-201892587 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 205.9" "Cell type enhanced" "Detected in many" "Bergmann glia: 36.3;Breast myoepithelial cells: 35.3;Decidual stromal cells: 53.4;Epididymal principal cells: 29.5;Extravillous trophoblasts: 38.1;Oligodendrocyte progenitor cells: 37.7;Oligodendrocytes: 46.5;Retinal pigment epithelial cells: 29.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 40.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "eosinophil: 24.6;intermediate monocyte: 8.1;neutrophil: 9.1;non-classical monocyte: 10.2" "Group enriched" "Detected in many" 10 "granulocytes: 24.6;monocytes: 10.2" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Skin - Fibroblasts_2, Spleen - Fibroblasts_1, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA061273, HPA067885" Uncertain NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 19: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 9 "HPA061273: , HPA067885: " "unprognostic (1.08e-1)" "unprognostic (3.42e-2)" "unprognostic (8.78e-2)" "unprognostic (3.10e-2)" "unprognostic (3.10e-3)" "unprognostic (9.63e-2)" "unprognostic (1.38e-1)" "unprognostic (2.57e-1)" "unprognostic (6.83e-3)" "unprognostic (4.38e-1)" "potential prognostic unfavorable (1.07e-4)" "unprognostic (2.14e-2)" "unprognostic (2.14e-2)" "unprognostic (1.13e-2)" "unprognostic (1.22e-1)" "unprognostic (2.01e-2)" "unprognostic (5.93e-2)" "unprognostic (3.49e-3)" "unprognostic (5.97e-1)" "unprognostic (6.82e-2)" "potential prognostic unfavorable (1.67e-4)" "unprognostic (2.70e-1)" "unprognostic (1.23e-1)" "unprognostic (9.65e-3)" "unprognostic (2.95e-2)" "unprognostic (1.06e-2)" "unprognostic (2.69e-1)" "unprognostic (4.94e-2)" "unprognostic (8.08e-2)" "unprognostic (6.59e-2)" "unprognostic (1.23e-1)" SHISA5 "hShisa5, SCOTIN" ENSG00000164054 "Shisa family member 5" Q8N114 3 48467798-48504826 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 336.0;Extravillous trophoblasts: 266.3;Migrating cytotrophoblasts: 345.8;Neutrophils: 365.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042295 Approved NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 24: Neutrophils - Innate immunity signal integration" 2 "HPA042295: " "unprognostic (2.95e-1)" "unprognostic (9.46e-2)" "unprognostic (2.41e-1)" "unprognostic (1.54e-1)" "unprognostic (3.06e-1)" "unprognostic (1.37e-1)" "unprognostic (1.50e-1)" "unprognostic (2.62e-2)" "unprognostic (2.04e-1)" "unprognostic (2.53e-3)" "unprognostic (1.44e-2)" "unprognostic (7.11e-2)" "unprognostic (3.21e-1)" "potential prognostic unfavorable (8.94e-4)" "unprognostic (5.42e-3)" "unprognostic (2.95e-2)" "potential prognostic unfavorable (2.29e-4)" "unprognostic (6.19e-3)" "unprognostic (1.00e-1)" "unprognostic (7.62e-2)" "unprognostic (7.35e-2)" "unprognostic (7.69e-2)" "unprognostic (4.88e-2)" "unprognostic (1.75e-2)" "unprognostic (3.66e-1)" "unprognostic (4.28e-2)" "unprognostic (8.35e-3)" "unprognostic (9.93e-2)" "unprognostic (5.96e-2)" "unprognostic (1.82e-1)" "unprognostic (1.82e-1)" SHISA6 FLJ45455 ENSG00000188803 "Shisa family member 6" Q6ZSJ9 17 11241213-11564063 "Predicted membrane proteins, Transporters" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.6;cervix: 15.8" "Cell type enhanced" "Detected in many" "Adipocytes: 377.9;Astrocytes: 136.5;Bergmann glia: 268.3;Brain excitatory neurons: 182.0;Brain inhibitory neurons: 164.6;Endometrial stromal cells: 224.8;Epicardial cells: 218.3;Mucous neck cells: 115.3;Oligodendrocyte progenitor cells: 152.9;Peritubular myoid cells: 220.3;Podocytes: 154.1" "Cell type enhanced" "Detected in all" "hippocampal CA4: 1756.1" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 6.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 6.7;thyroid cancer: 1.9" "Colon - Fibroblasts, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" HPA023440 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" 20 "Nucleoplasm, Plasma membrane" "HPA023440: " "unprognostic (1.24e-2)" "unprognostic (7.95e-2)" "unprognostic (2.21e-3)" "validated prognostic unfavorable (9.49e-5)" "validated prognostic unfavorable (3.08e-4)" "unprognostic (2.04e-3)" "unprognostic (1.78e-1)" "unprognostic (1.34e-1)" "unprognostic (2.15e-1)" "unprognostic (2.16e-1)" "unprognostic (2.14e-2)" "unprognostic (1.03e-1)" SHISA7 ENSG00000187902 "Shisa family member 7" A6NL88 19 55428740-55443300 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 24.6" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 24.6;Brain inhibitory neurons: 37.6;Oligodendrocyte progenitor cells: 57.5;Oligodendrocytes: 24.7;Other brain neurons: 20.6;Retinal amacrine cells: 12.0;Somatotrophs: 9.8;Thyrotrophs: 6.4" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in single" 12 "Glioblastoma Multiforme (TCGA): 3.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 1.7;Neuroblastoma: 2.0" "Adrenal gland - Adrenal medulla cells, Pancreas - Alpha cells, Pituitary gland - Somatotropes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058935 Uncertain Approved Cytosol NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" Cytosol "HPA058935: " "unprognostic (9.32e-2)" "potential prognostic favorable (1.41e-5)" SHISA8 "C22orf17, Orf26" ENSG00000234965 "Shisa family member 8" B8ZZ34 22 41909543-41915074 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 57.1" "Group enriched" "Detected in some" 5 "Breast lactating cells: 276.8;Oocytes: 271.7;Retinal horizontal cells: 272.5" "Cell type enhanced" "Detected in many" "CGE interneuron: 88.0;midbrain-derived inhibitory: 181.7;upper rhombic lip: 99.7" "Low cancer specificity" "Detected in single" "Region enriched" "Detected in many" 8 "cerebellum: 103.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Lung - B-cells (Lung), Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Gonadotropes" "Group enriched" "Detected in many" 4 "cerebellum: 7.8;olfactory bulb: 15.7;white matter: 4.0" "Low region specificity" "Detected in all" HPA059173 Uncertain NA NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 4: Breast lactating luminal cells - Lactation" "HPA059173: " "unprognostic (1.34e-1)" SHISA9 ENSG00000237515 "Shisa family member 9" B4DS77 16 12901598-13240416 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 12.2" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 234.0;Brain excitatory neurons: 423.6;Brain inhibitory neurons: 570.2;Corticotrophs: 572.4;Loop of henle epithelial cells: 166.1;Oligodendrocyte progenitor cells: 655.0;Other brain neurons: 333.8;Prostatic glandular cells: 153.1;Schwann cells: 236.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 23.0" "Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Pituitary gland - Corticotropes, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072399 Approved Vesicles,Cytosol NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 24: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 35: Neurons - Synaptic function & neurogenesis" "Vesicles, Cytosol" "HPA072399: " "unprognostic (8.26e-2)" "unprognostic (2.36e-3)" "unprognostic (2.68e-1)" "unprognostic (3.80e-2)" "unprognostic (1.54e-2)" "unprognostic (1.04e-2)" "unprognostic (1.41e-1)" "unprognostic (2.52e-3)" "unprognostic (6.06e-2)" "validated prognostic favorable (1.33e-6)" "validated prognostic favorable (1.18e-5)" "unprognostic (2.21e-1)" "unprognostic (5.08e-2)" "unprognostic (2.65e-1)" "unprognostic (6.40e-2)" "unprognostic (6.12e-3)" "unprognostic (1.14e-2)" "unprognostic (4.36e-2)" "unprognostic (1.33e-1)" "unprognostic (1.48e-1)" "unprognostic (1.34e-2)" "unprognostic (1.79e-1)" "unprognostic (2.89e-1)" "unprognostic (6.48e-3)" "unprognostic (3.04e-1)" "unprognostic (8.94e-2)" "unprognostic (8.18e-3)" SHISAL1 KIAA1644 ENSG00000138944 "Shisa like 1" Q3SXP7 22 44243665-44312951 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.1;endometrium 1: 29.1;smooth muscle: 27.4" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 11.0;Brain inhibitory neurons: 11.6;Decidual stromal cells: 18.1;Endometrial stromal cells: 6.6;Lactotrophs: 21.4;Oocytes: 9.2;Other brain neurons: 19.1;Pancreatic islet cells: 5.2;Retinal bipolar cells: 10.9;Smooth muscle cells: 19.5" "Cell type enhanced" "Detected in many" "mammillary body: 71.5;thalamic excitatory: 60.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 17.4" "Adipose subcutaneous - Smooth muscle cells, Pituitary gland - Lactotropes, Stomach - Fibroblasts, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051178 Uncertain Approved Vesicles,Cytosol No No "Cluster 65: Brain - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 109: Neurons - Neuronal signaling" 43 "Vesicles, Cytosol" "HPA051178: " "unprognostic (1.93e-2)" "unprognostic (5.46e-3)" "unprognostic (5.73e-3)" "unprognostic (1.69e-1)" "unprognostic (1.35e-1)" "unprognostic (1.45e-3)" "unprognostic (1.16e-1)" "unprognostic (4.24e-2)" "unprognostic (8.02e-2)" "unprognostic (1.90e-1)" "unprognostic (1.39e-2)" "unprognostic (1.69e-1)" "unprognostic (4.92e-2)" "unprognostic (9.49e-2)" "unprognostic (3.42e-2)" "unprognostic (2.80e-2)" "unprognostic (1.45e-2)" "unprognostic (4.62e-2)" SHISAL2A "FAM159A, MGC52498" ENSG00000182183 "Shisa like 2A" Q6UWV7 1 52633168-52669683 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.9;intestine: 2.9;lymphoid tissue: 5.3" "Cell type enhanced" "Detected in many" "B-cells: 103.3;Bergmann glia: 24.9;Innate lymphoid cells: 31.5;Microglia: 20.9;Neutrophil progenitors: 22.0;Neutrophils: 34.2;NK-cells: 33.3;Plasma cells: 16.4;T-cells: 36.9" "Group enriched" "Detected in many" 7 "Bergmann glia: 29.5;central nervous system macrophage: 30.9;leukocyte: 56.7" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 6 "hypothalamus: 18.1" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 10.1;NK-cells: 5.9;T-cells: 7.0" "Group enriched" "Detected in some" 9 "Leukemia: 1.3;lymphoma: 3.3;Myeloma: 4.8" "Adipose visceral - T-cells, Liver - T-cells, Pituitary gland - Somatotropes, Prostate - T-cells, Spleen - B-cells (Spleen)" "Region enhanced" "Detected in some" "hypothalamus: 4.0" "Low region specificity" "Detected in many" HPA030744 Uncertain NA NA "Cluster 24: Non-specific - Transcription" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 2 "HPA030744: " "unprognostic (2.38e-3)" "unprognostic (7.06e-2)" "unprognostic (2.03e-1)" "unprognostic (3.69e-2)" "unprognostic (1.26e-1)" "unprognostic (4.16e-1)" "unprognostic (1.33e-1)" "unprognostic (6.73e-3)" "unprognostic (1.69e-2)" "unprognostic (1.10e-1)" "unprognostic (5.98e-2)" "unprognostic (1.44e-1)" "unprognostic (7.81e-2)" "unprognostic (1.06e-1)" SHISAL2B FAM159B ENSG00000145642 "Shisa like 2B" A6NKW6 5 64690442-64718190 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 9 "brain: 3.3;pancreas: 4.6;stomach 1: 2.7" "Cell type enriched" "Detected in some" 4 "Pancreatic islet cells: 98.6" "Cell type enhanced" "Detected in some" "CGE interneuron: 5.7;splatter: 3.9" "Cancer enriched" "Detected in single" 12 "Pancreatic Adenocarcinoma (TCGA): 3.7" "Region enhanced" "Detected in many" "hypothalamus: 6.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 19 "Rhabdoid: 6.8" "Pancreas - Beta cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA011778 Enhanced NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" "HPA011778: " "unprognostic (1.66e-2)" "unprognostic (1.29e-1)" "unprognostic (1.37e-1)" SHKBP1 "PP203, Sb1" ENSG00000160410 "SH3KBP1 binding protein 1" Q8TBC3 19 40576853-40591399 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 124.1" "Cell type enriched" "Detected in many" 4 "Neutrophils: 511.4" "Cell type enhanced" "Detected in many" "leukocyte: 27.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Neutrophils_2, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041887 Uncertain Approved "Cell Junctions" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 11: White matter - Signal transduction" "Cluster 35: RS4;11 - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" 40 "Cell Junctions" "HPA041887: " "unprognostic (5.61e-2)" "unprognostic (1.35e-1)" "unprognostic (8.62e-2)" "unprognostic (8.72e-3)" "unprognostic (2.54e-1)" "unprognostic (2.20e-1)" "unprognostic (2.27e-1)" "unprognostic (3.11e-1)" "unprognostic (2.03e-1)" "unprognostic (1.26e-1)" "unprognostic (1.53e-3)" "unprognostic (1.84e-2)" "unprognostic (5.13e-2)" "potential prognostic unfavorable (6.32e-4)" "unprognostic (1.15e-2)" "unprognostic (1.47e-2)" "unprognostic (1.22e-1)" "unprognostic (2.17e-1)" "unprognostic (5.53e-2)" "unprognostic (2.79e-1)" "unprognostic (5.28e-2)" "unprognostic (1.88e-1)" "potential prognostic unfavorable (4.18e-4)" "unprognostic (1.63e-1)" "unprognostic (5.02e-1)" "unprognostic (4.52e-2)" "unprognostic (2.44e-2)" "unprognostic (1.70e-2)" "unprognostic (1.28e-1)" "unprognostic (2.57e-1)" "unprognostic (6.47e-2)" SHLD1 "C20orf196, FLJ25067, RINN3" ENSG00000171984 "Shieldin complex subunit 1" Q8IYI0 20 5750393-5864395 "Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cell type enhanced" "Detected in all" "endothelial cell: 169.1" "Cancer enhanced" "Detected in all" "Uterine Corpus Endometrial Carcinoma (TCGA): 50.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "lymphoma: 35.7" "Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040749 Approved Approved "Endoplasmic reticulum,Golgi apparatus,Vesicles" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 25: Non-specific - Transcription" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 10 "Endoplasmic reticulum, Golgi apparatus, Vesicles" "HPA040749: " "unprognostic (1.37e-1)" "unprognostic (1.08e-1)" "unprognostic (3.49e-3)" "unprognostic (3.85e-2)" "unprognostic (6.47e-2)" "unprognostic (1.32e-1)" "unprognostic (1.71e-3)" "unprognostic (2.10e-1)" "unprognostic (8.45e-3)" "potential prognostic favorable (3.30e-4)" "unprognostic (3.27e-1)" "unprognostic (3.09e-2)" "potential prognostic unfavorable (4.75e-4)" "unprognostic (3.02e-2)" "unprognostic (1.04e-1)" "unprognostic (1.35e-2)" "unprognostic (1.05e-1)" "unprognostic (2.61e-2)" "unprognostic (1.73e-1)" "unprognostic (7.31e-2)" "unprognostic (2.25e-2)" "unprognostic (1.29e-2)" "unprognostic (2.60e-1)" "unprognostic (8.43e-2)" "unprognostic (9.37e-2)" "unprognostic (9.66e-2)" "unprognostic (3.89e-1)" "unprognostic (2.81e-2)" "unprognostic (1.04e-2)" SHLD2 "bA163M19.1, FAM35A, FAM35A1, MGC5560, RINN2" ENSG00000122376 "Shieldin complex subunit 2" Q86V20 10 87094161-87191465 "Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036582, HPA057506" Approved Supported "Nucleoplasm,Actin filaments" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 76: Non-specific - Metabolism" "Cluster 18: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 5 Nucleoplasm "Actin filaments" "HPA036582: , HPA057506: " "unprognostic (5.89e-2)" "unprognostic (3.35e-2)" "potential prognostic favorable (4.75e-4)" "unprognostic (8.80e-2)" "unprognostic (1.19e-2)" "unprognostic (1.18e-2)" "potential prognostic favorable (9.58e-4)" "unprognostic (6.81e-2)" "unprognostic (6.78e-2)" "potential prognostic favorable (2.50e-7)" "unprognostic (1.31e-2)" "unprognostic (6.77e-2)" "unprognostic (1.61e-1)" "unprognostic (1.10e-1)" "unprognostic (9.42e-3)" "unprognostic (2.31e-1)" "unprognostic (8.27e-2)" "unprognostic (1.67e-1)" "unprognostic (9.34e-2)" "unprognostic (5.24e-2)" "unprognostic (1.45e-2)" "unprognostic (1.46e-1)" "validated prognostic favorable (4.21e-4)" "validated prognostic favorable (7.62e-6)" "unprognostic (2.72e-1)" "unprognostic (7.76e-2)" "unprognostic (2.62e-1)" "potential prognostic unfavorable (8.67e-4)" "unprognostic (4.02e-2)" SHLD3 "AC008560.1, CTC-534A2.2, FLJ26957, RINN1" ENSG00000253251 "Shieldin complex subunit 3" Q6ZNX1 5 65625027-65630928 "Essential proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 16.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068764 Approved Approved Nucleoplasm,Nucleoli No No "Cluster 19: Eosinophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 34: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 1 "Nucleoplasm, Nucleoli" "HPA068764: " "unprognostic (3.99e-2)" "unprognostic (1.54e-1)" "unprognostic (1.37e-1)" "unprognostic (3.32e-1)" "unprognostic (2.46e-2)" "unprognostic (2.80e-1)" "unprognostic (2.03e-2)" "unprognostic (7.64e-2)" "unprognostic (1.40e-1)" "unprognostic (2.43e-1)" "unprognostic (3.89e-1)" "unprognostic (8.53e-2)" "unprognostic (2.24e-3)" "unprognostic (2.33e-1)" "unprognostic (9.38e-2)" "unprognostic (3.66e-2)" "unprognostic (1.14e-1)" "unprognostic (1.50e-1)" "unprognostic (1.55e-1)" "potential prognostic favorable (2.73e-4)" "potential prognostic unfavorable (3.08e-4)" "potential prognostic unfavorable (1.45e-4)" "unprognostic (1.59e-2)" "unprognostic (1.53e-1)" "unprognostic (2.83e-1)" "unprognostic (2.54e-1)" "unprognostic (1.19e-1)" "unprognostic (3.92e-2)" "unprognostic (1.88e-1)" SHMT1 "cSHMT, MGC15229, MGC24556, SHMT" ENSG00000176974 "Serine hydroxymethyltransferase 1" P34896 17 18327860-18363563 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "One-carbon metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 156.8;liver: 375.9" "Cell type enriched" "Detected in many" 4 "Proximal tubule cells: 220.2" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 47.8" "Cancer enhanced" "Detected in all" "Kidney Renal Papillary Cell Carcinoma (TCGA): 88.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Macrophages, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Pituitary gland - Undifferentiated cells (Pituitary gland), Spleen - Macrophages, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA023314, HPA078682" Enhanced Supported Nucleoplasm,Cytosol NA NA 1900000 "Cluster 16: Non-specific - Cell proliferation" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 42: Non-specific - Unknown function" "Cluster 88: Proximal tubular cells - Transmembrane transport" 10 Cytosol Nucleoplasm "HPA023314: , HPA078682: " "unprognostic (1.86e-3)" "unprognostic (3.34e-1)" "unprognostic (4.69e-3)" "unprognostic (1.31e-1)" "unprognostic (1.18e-1)" "unprognostic (5.51e-2)" "unprognostic (7.19e-3)" "unprognostic (4.00e-2)" "potential prognostic favorable (7.26e-4)" "unprognostic (5.20e-1)" "potential prognostic favorable (8.74e-8)" "unprognostic (4.27e-2)" "potential prognostic favorable (7.19e-4)" "unprognostic (4.90e-3)" "potential prognostic favorable (5.07e-4)" "unprognostic (4.97e-2)" "unprognostic (1.01e-1)" "unprognostic (2.20e-2)" "unprognostic (3.06e-1)" "unprognostic (8.82e-2)" "unprognostic (3.52e-1)" "unprognostic (3.73e-2)" "unprognostic (2.16e-1)" "unprognostic (2.49e-2)" "unprognostic (1.52e-1)" "unprognostic (1.27e-2)" "unprognostic (6.96e-2)" "unprognostic (9.15e-2)" "unprognostic (1.06e-1)" "unprognostic (3.26e-3)" "unprognostic (2.06e-1)" SHMT2 "mSHMT, SHMT" ENSG00000182199 "Serine hydroxymethyltransferase 2" P34897 12 57229573-57234935 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "One-carbon metabolism" Transferase "Cardiomyopathy, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 222.9" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 122.5;Esophageal suprabasal cells: 78.4;Hepatocytes: 205.2;Migrating cytotrophoblasts: 72.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020543, HPA020549" Enhanced Supported Microtubules,Mitochondria NA NA 230000 "Cluster 14: Non-specific - Unknown function" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 27: Non-specific - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 27: Non-specific - Cell proliferation" 45 Mitochondria Microtubules "HPA020543: , HPA020549: " "unprognostic (1.71e-2)" "potential prognostic unfavorable (1.86e-4)" "unprognostic (1.75e-1)" "unprognostic (1.11e-2)" "unprognostic (5.19e-2)" "unprognostic (5.97e-2)" "unprognostic (2.53e-2)" "unprognostic (6.32e-2)" "unprognostic (7.16e-2)" "potential prognostic unfavorable (7.20e-6)" "unprognostic (1.72e-2)" "unprognostic (1.46e-1)" "unprognostic (2.92e-2)" "unprognostic (3.67e-2)" "potential prognostic unfavorable (1.45e-4)" "unprognostic (1.13e-2)" "unprognostic (1.11e-3)" "unprognostic (2.22e-1)" "unprognostic (3.25e-1)" "unprognostic (1.06e-1)" "unprognostic (3.28e-1)" "unprognostic (5.07e-2)" "unprognostic (3.07e-2)" "unprognostic (7.11e-2)" "unprognostic (5.21e-2)" "unprognostic (3.30e-1)" "unprognostic (3.85e-2)" "unprognostic (1.41e-1)" "unprognostic (1.28e-1)" "unprognostic (2.53e-1)" "unprognostic (3.17e-2)" SHOC1 "C9orf84, FLJ32779, MZIP2, Zip2" ENSG00000165181 "Shortage in chiasmata 1" Q5VXU9 9 111686171-111795008 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Meiosis "DNA-binding, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 20.5" "Cell type enhanced" "Detected in many" "Adipocytes: 376.5;Cardiomyocytes: 363.2;Early primary spermatocytes: 178.5;Epicardial cells: 413.9;Fibro-adipogenic progenitors: 228.4;Late primary spermatocytes: 167.5;Neutrophils: 203.3;Renal collecting duct intercalated cells: 392.3;Sertoli cells: 373.1" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in some" 6 "Kidney Chromophobe (TCGA): 12.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 13 "neutrophil: 1.3" "Lineage enriched" "Detected in single" 13 "granulocytes: 1.3" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 2.8" "Adrenal gland - Adrenal cortex cells, Kidney - Intercalated cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA052214 Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 57: Testis - Spermatogenesis" "Cluster 55: Non-specific - Transcription" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" Nucleoplasm "Nuclear bodies" "HPA052214: " "unprognostic (1.27e-2)" "unprognostic (1.30e-3)" "unprognostic (3.91e-2)" "unprognostic (2.37e-2)" "unprognostic (1.03e-3)" "unprognostic (7.36e-2)" SHOC2 "KIAA0862, SOC-2, SOC2, SUR-8, SUR8" ENSG00000108061 "SHOC2 leucine rich repeat scaffold protein" Q9UQ13 10 110919367-111017307 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 550.1;Neutrophils: 1192.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009164, HPA048134" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 61: Non-specific - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 16 "Nucleoplasm, Cytosol" "HPA009164: , HPA048134: " "unprognostic (2.15e-1)" "unprognostic (6.48e-2)" "unprognostic (1.21e-1)" "unprognostic (1.27e-1)" "unprognostic (9.59e-2)" "unprognostic (7.98e-2)" "unprognostic (2.39e-1)" "unprognostic (5.01e-2)" "unprognostic (1.71e-1)" "unprognostic (1.98e-1)" "potential prognostic favorable (5.21e-6)" "unprognostic (4.04e-2)" "unprognostic (3.66e-1)" "unprognostic (7.03e-3)" "unprognostic (4.98e-2)" "unprognostic (6.73e-2)" "unprognostic (2.51e-1)" "unprognostic (1.91e-1)" "unprognostic (1.56e-1)" "unprognostic (4.06e-3)" "potential prognostic unfavorable (5.03e-6)" "unprognostic (1.41e-1)" "unprognostic (3.82e-2)" "unprognostic (1.22e-1)" "unprognostic (1.25e-1)" "unprognostic (4.60e-1)" "unprognostic (1.05e-1)" "unprognostic (2.08e-1)" "unprognostic (5.44e-2)" "unprognostic (4.77e-2)" "unprognostic (2.10e-1)" SHOX "GCFX, PHOG, SHOXY, SS" ENSG00000185960 "Short stature homeobox" O15266 X 624344-659411 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in single" "Cell type enhanced" "Detected in some" "Cholangiocytes: 2.0;Cone photoreceptor cells: 2.1;Epicardial cells: 2.3;Fibro-adipogenic progenitors: 5.7;Fibroblasts: 2.9;Foveolar cells: 2.3;Migrating cytotrophoblasts: 2.6;Myonuclei: 11.0;Myosatellite cells: 5.0;Parietal cells: 1.8;Pericytes: 3.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 5.1" "Lineage enriched" "Detected in single" 6 "granulocytes: 5.1" "Cancer enriched" "Detected in some" 5 "Rhabdoid: 6.2" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "midbrain: 2.3;thalamus: 3.0" "HPA035141, HPA060931" Enhanced Nucleoplasm,Vesicles NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 2 Nucleoplasm Vesicles "HPA035141: , HPA060931: " "unprognostic (1.14e-1)" "unprognostic (2.05e-1)" "unprognostic (1.85e-1)" "unprognostic (1.83e-1)" "unprognostic (1.77e-2)" "unprognostic (2.44e-1)" "unprognostic (2.96e-1)" "unprognostic (1.79e-1)" "unprognostic (1.94e-2)" SHOX2 "OG12, OG12X, SHOT" ENSG00000168779 "Short stature homeobox 2" O60902 3 158095905-158106420 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 5.4;blood vessel: 10.5" "Cell type enriched" "Detected in some" 5 "Early spermatids: 128.6" "Cell type enriched" "Detected in some" 9 "thalamic excitatory: 59.3" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 6.9" "Region enhanced" "Detected in many" "thalamus: 44.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Group enriched" "Detected in many" 5 "midbrain: 36.0;thalamus: 54.8" "Group enriched" "Detected in some" 6 "midbrain: 11.9;pons: 18.2;thalamus: 35.7" NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" "unprognostic (8.10e-2)" "unprognostic (2.33e-1)" "unprognostic (1.88e-1)" "unprognostic (1.38e-2)" "unprognostic (8.41e-2)" "unprognostic (4.19e-3)" "unprognostic (4.37e-2)" "unprognostic (2.29e-2)" "unprognostic (3.60e-1)" "unprognostic (5.27e-1)" "unprognostic (5.64e-2)" "unprognostic (1.44e-1)" SHPK "CARKL, SHK" ENSG00000197417 Sedoheptulokinase Q9UHJ6 17 3608240-3636250 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 35.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024361, HPA064939" Enhanced Approved "Nucleoplasm,Nuclear speckles" NA NA 320000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 77: Intestine - Digestion" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 70: Intestinal goblet cells - Mucin production" 6 "Nucleoplasm, Nuclear speckles" "HPA024361: , HPA064939: " "unprognostic (3.96e-2)" "unprognostic (1.22e-1)" "unprognostic (2.83e-2)" "unprognostic (5.48e-2)" "unprognostic (1.24e-2)" "unprognostic (2.08e-2)" "unprognostic (1.68e-2)" "unprognostic (1.20e-2)" "unprognostic (8.48e-2)" "unprognostic (1.00e-2)" "validated prognostic favorable (1.97e-4)" "validated prognostic favorable (8.51e-4)" "potential prognostic favorable (3.41e-5)" "unprognostic (3.29e-2)" "potential prognostic favorable (3.63e-4)" "unprognostic (1.61e-1)" "unprognostic (2.79e-1)" "potential prognostic unfavorable (2.45e-4)" "unprognostic (3.35e-1)" "unprognostic (1.59e-1)" "unprognostic (2.45e-1)" "unprognostic (2.24e-1)" "unprognostic (2.85e-2)" "unprognostic (1.83e-1)" "unprognostic (1.29e-1)" "unprognostic (3.61e-2)" "unprognostic (2.08e-1)" "unprognostic (1.63e-1)" "unprognostic (1.44e-1)" "unprognostic (2.32e-2)" "unprognostic (8.30e-2)" SHPRH "bA545I5.2, FLJ90837, KIAA2023" ENSG00000146414 "SNF2 histone linker PHD RING helicase" Q149N8 6 145864245-145964423 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Helicase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034854, HPA044852" Approved Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 42: Retina - Visual perception" "Cluster 2: Neurons - Nucleosome" "Cluster 28: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" 17 "Nucleoplasm, Nuclear membrane" Cytosol "HPA034854: , HPA044852: " "unprognostic (1.39e-1)" "unprognostic (4.95e-3)" "unprognostic (4.41e-3)" "unprognostic (5.13e-2)" "unprognostic (5.67e-2)" "unprognostic (6.87e-3)" "unprognostic (7.02e-3)" "unprognostic (9.36e-3)" "unprognostic (1.52e-2)" "unprognostic (1.28e-2)" "potential prognostic favorable (2.73e-4)" "unprognostic (2.35e-3)" "unprognostic (1.13e-1)" "unprognostic (2.35e-2)" "unprognostic (1.08e-1)" "unprognostic (1.39e-1)" "unprognostic (3.44e-1)" "unprognostic (4.86e-1)" "unprognostic (2.12e-3)" "potential prognostic unfavorable (6.19e-4)" "unprognostic (5.60e-2)" "unprognostic (4.96e-2)" "unprognostic (2.28e-2)" "unprognostic (8.22e-2)" "validated prognostic favorable (1.55e-5)" "validated prognostic favorable (4.41e-4)" "unprognostic (8.14e-2)" "unprognostic (7.36e-2)" "unprognostic (3.36e-1)" "unprognostic (3.54e-2)" "unprognostic (5.76e-2)" SHQ1 "FLJ10539, Shq1p" ENSG00000144736 "SHQ1, H/ACA ribonucleoprotein assembly factor" Q6PI26 3 72749277-72861914 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Disease variant, Dystonia, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042792 Uncertain Supported Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 15 Nucleoplasm "HPA042792: " "unprognostic (1.84e-1)" "unprognostic (5.56e-2)" "unprognostic (2.42e-1)" "unprognostic (2.78e-1)" "potential prognostic favorable (5.70e-4)" "unprognostic (1.14e-1)" "unprognostic (1.13e-2)" "unprognostic (1.74e-1)" "unprognostic (7.44e-2)" "unprognostic (2.85e-2)" "potential prognostic favorable (7.20e-5)" "unprognostic (2.35e-2)" "unprognostic (3.96e-2)" "validated prognostic unfavorable (4.13e-4)" "validated prognostic unfavorable (9.45e-4)" "unprognostic (1.26e-1)" "potential prognostic unfavorable (7.52e-4)" "unprognostic (1.09e-1)" "unprognostic (8.98e-2)" "unprognostic (8.45e-2)" "unprognostic (1.44e-1)" "unprognostic (2.07e-1)" "unprognostic (3.43e-2)" "unprognostic (2.10e-2)" "unprognostic (1.33e-3)" "unprognostic (1.73e-1)" "unprognostic (1.60e-1)" "unprognostic (3.83e-3)" "unprognostic (2.52e-2)" "unprognostic (5.72e-2)" "unprognostic (2.56e-1)" SHROOM1 "APXL2, KIAA1960" ENSG00000164403 "Shroom family member 1" Q2M3G4 5 132822141-132830659 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 112.0;prostate: 67.3;urinary bladder: 62.7" "Cell type enhanced" "Detected in many" "Colonocytes: 106.4;Enterocytes: 61.4;Foveolar cells: 49.4;Hepatocytes: 86.7;Papillary tip epithelial cells: 74.4;Prostatic club cells: 134.4;Prostatic glandular cells: 57.1;Prostatic hillock cells: 85.4;Urothelial cells: 144.2" "Cell type enhanced" "Detected in all" "endothelial cell: 112.2;oligodendrocyte: 58.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037690, HPA037691" Uncertain Approved Vesicles NA NA "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 6: Non-specific - Immune response" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 69: Urothelial cells - Basic cellular functions" 2 Vesicles "HPA037690: , HPA037691: " "potential prognostic favorable (8.57e-4)" "unprognostic (1.97e-1)" "unprognostic (5.79e-2)" "unprognostic (4.07e-3)" "unprognostic (1.99e-1)" "unprognostic (1.17e-2)" "unprognostic (1.74e-2)" "potential prognostic unfavorable (1.88e-5)" "unprognostic (2.10e-1)" "potential prognostic unfavorable (2.87e-4)" "unprognostic (1.22e-1)" "unprognostic (2.56e-1)" "unprognostic (7.51e-2)" "unprognostic (3.96e-2)" "unprognostic (1.31e-3)" "unprognostic (4.34e-2)" "unprognostic (3.65e-2)" "unprognostic (7.07e-3)" "potential prognostic unfavorable (4.82e-4)" "unprognostic (8.86e-2)" "unprognostic (4.24e-2)" "unprognostic (3.89e-2)" "unprognostic (5.15e-2)" "unprognostic (4.26e-3)" "unprognostic (1.67e-2)" "potential prognostic unfavorable (1.59e-4)" "unprognostic (3.69e-1)" "unprognostic (1.42e-1)" "unprognostic (4.48e-2)" "unprognostic (2.39e-1)" "unprognostic (2.40e-1)" SHROOM2 APXL ENSG00000146950 "Shroom family member 2" Q13796 X 9786429-9949443 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 19.3" "Cell type enhanced" "Detected in many" "Peritubular myoid cells: 149.0;Renal collecting duct intercalated cells: 160.1;Rod photoreceptor cells: 107.2;Tuft cells: 138.3" "Cell type enhanced" "Detected in all" "endothelial cell: 183.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 17.1" "Prostate - Prostate glandular cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA051646, HPA061435" Approved Approved "Plasma membrane,Cell Junctions,Cytosol" No No "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 104: Brain endothelial cells - Blood brain barrier" "Plasma membrane, Cell Junctions" Cytosol "HPA051646: , HPA061435: " "unprognostic (8.83e-2)" "unprognostic (1.35e-2)" "unprognostic (8.62e-2)" "unprognostic (2.46e-2)" "unprognostic (6.10e-2)" "unprognostic (1.11e-1)" "unprognostic (2.42e-2)" "unprognostic (5.17e-2)" "unprognostic (2.60e-2)" "unprognostic (1.28e-1)" "potential prognostic favorable (4.71e-7)" "unprognostic (3.83e-3)" "unprognostic (1.97e-1)" "unprognostic (3.19e-2)" "unprognostic (2.91e-3)" "unprognostic (3.06e-1)" "unprognostic (2.26e-1)" "unprognostic (7.88e-2)" "unprognostic (1.27e-3)" "unprognostic (3.35e-1)" "unprognostic (8.77e-2)" "unprognostic (2.39e-2)" "unprognostic (1.30e-2)" "unprognostic (1.92e-1)" "unprognostic (4.12e-3)" "unprognostic (6.76e-3)" "unprognostic (3.39e-1)" "unprognostic (1.12e-1)" "unprognostic (3.43e-1)" "unprognostic (1.76e-1)" "unprognostic (1.75e-2)" SHROOM3 "APXL3, KIAA1481, SHRM, ShrmL" ENSG00000138771 "Shroom family member 3" Q8TF72 4 76435229-76783253 "Plasma proteins, Predicted intracellular proteins" "Cell shape" "Actin-binding, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 1116.1;Endometrial ciliated cells: 1119.2;Endometrial glandular cells: 3503.2;Endometrial luminal cells: 1143.7;Pituitary stem cells: 1439.0;Renal collecting duct intercalated cells: 1182.9" "Cell type enhanced" "Detected in all" "astrocyte: 589.8;Bergmann glia: 498.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Breast - Breast glandular cells, Skin - Eccrine sweat gland cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA047784 Enhanced NA NA "Cluster 17: Intestine - Digestion" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 51: Secretory epithelial cells - Mixed function" 19 "HPA047784: " "unprognostic (1.04e-1)" "unprognostic (4.04e-2)" "unprognostic (1.56e-1)" "unprognostic (5.55e-2)" "unprognostic (7.63e-3)" "unprognostic (1.97e-2)" "unprognostic (5.81e-2)" "potential prognostic unfavorable (3.37e-5)" "unprognostic (1.48e-1)" "unprognostic (2.54e-1)" "potential prognostic favorable (6.20e-7)" "unprognostic (6.61e-3)" "unprognostic (3.59e-2)" "unprognostic (2.10e-2)" "unprognostic (3.53e-3)" "unprognostic (2.42e-3)" "unprognostic (1.39e-1)" "unprognostic (2.31e-2)" "unprognostic (2.15e-1)" "unprognostic (8.23e-2)" "unprognostic (1.83e-1)" "unprognostic (1.12e-3)" "unprognostic (2.25e-2)" "unprognostic (5.11e-2)" "unprognostic (1.26e-2)" "unprognostic (1.10e-1)" "unprognostic (2.09e-1)" "unprognostic (1.22e-1)" "unprognostic (2.23e-1)" "unprognostic (1.34e-1)" "unprognostic (2.83e-1)" SHROOM4 KIAA1202 ENSG00000158352 "Shroom family member 4" Q9ULL8 X 50586796-50814302 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin-binding, Developmental protein" "Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 208.8;Oligodendrocyte progenitor cells: 134.5;Oligodendrocytes: 583.8;Pituicytes/FSCs: 554.2;Proximal tubule cells: 226.7;Renal connecting tubule cells: 137.0;Vascular endothelial cells: 214.2" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 434.4;endothelial cell: 291.3;oligodendrocyte: 807.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 4.6" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Lung - Endothelial cells, Minor Salivary Gland - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA010089, HPA010565" Uncertain Approved "Nucleoplasm,Vesicles,Focal adhesion sites" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 30: White matter - Myelination" "Cluster 69: Skin cancer - ECM organization" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" "Focal adhesion sites" "Nucleoplasm, Vesicles" "HPA010089: , HPA010565: " "unprognostic (3.68e-1)" "unprognostic (4.51e-2)" "unprognostic (7.86e-3)" "unprognostic (1.61e-2)" "unprognostic (1.54e-1)" "unprognostic (2.10e-1)" "unprognostic (9.97e-2)" "unprognostic (1.76e-1)" "unprognostic (1.35e-2)" "unprognostic (2.41e-1)" "validated prognostic favorable (2.01e-7)" "validated prognostic favorable (4.22e-4)" "unprognostic (1.67e-1)" "unprognostic (2.21e-2)" "unprognostic (2.56e-2)" "unprognostic (3.36e-1)" "unprognostic (4.76e-3)" "unprognostic (2.50e-1)" "unprognostic (1.07e-1)" "unprognostic (7.68e-3)" "unprognostic (2.76e-1)" "unprognostic (8.99e-2)" "unprognostic (1.77e-3)" "unprognostic (1.20e-1)" "unprognostic (1.53e-1)" "unprognostic (2.29e-1)" "unprognostic (2.64e-1)" "unprognostic (2.56e-2)" "unprognostic (1.48e-1)" SHTN1 "KIAA1598, shootin-1, shootin1" ENSG00000187164 "Shootin 1" A0MZ66 10 116881477-117126586 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 53.0" "Cell type enhanced" "Detected in all" "Choroid plexus epithelial cells: 523.9;Corticotrophs: 439.8;Gonadotrophs: 591.2;Lactotrophs: 499.3;Microglia: 708.4;Oligodendrocytes: 1442.2;Somatotrophs: 476.9" "Cell type enhanced" "Detected in all" "oligodendrocyte: 1894.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 30 "classical monocyte: 19.8;intermediate monocyte: 12.9;myeloid DC: 19.3;non-classical monocyte: 6.6;plasmacytoid DC: 12.9" "Group enriched" "Detected in many" 42 "dendritic cells: 19.3;monocytes: 19.8" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Spleen - Macrophages, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037942, HPA037943, HPA075224" Enhanced Approved Approved "Nucleoplasm,Plasma membrane,Centrosome,Basal body,Cytosol" NA NA 5600 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 7: Liver cancer - Metabolism" "Cluster 80: Oligodendrocytes - Myelination" 20 "Plasma membrane, Cytosol" "Nucleoplasm, Centrosome, Basal body" "HPA037942: , HPA037943: , HPA075224: " "unprognostic (4.15e-2)" "unprognostic (3.57e-2)" "unprognostic (1.32e-1)" "unprognostic (2.87e-1)" "unprognostic (9.45e-2)" "unprognostic (5.51e-2)" "unprognostic (1.94e-1)" "unprognostic (4.31e-1)" "unprognostic (1.62e-2)" "potential prognostic favorable (4.07e-4)" "unprognostic (3.17e-1)" "unprognostic (6.97e-2)" "unprognostic (1.81e-1)" "unprognostic (5.84e-2)" "unprognostic (1.76e-1)" "unprognostic (2.82e-2)" "unprognostic (1.78e-2)" "unprognostic (1.42e-2)" "unprognostic (6.00e-3)" "unprognostic (1.54e-2)" "unprognostic (9.76e-2)" "unprognostic (2.34e-2)" "unprognostic (5.54e-3)" "unprognostic (3.81e-1)" "unprognostic (2.60e-2)" "unprognostic (1.74e-1)" "unprognostic (1.20e-1)" "unprognostic (1.04e-1)" "unprognostic (1.45e-1)" SI ENSG00000090402 Sucrase-isomaltase P14410 3 164978898-165078496 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Glycosidase, Hydrolase, Multifunctional enzyme" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 150 "intestine: 513.4" "Cell type enriched" "Detected in some" 6 "Enterocytes: 1438.8" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in some" "Stomach Adenocarcinoma (TCGA): 9.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 1.2;prostate cancer: 1.7" "Colon - Colon enterocytes, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA011897 Enhanced NA NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 1: Enterocytes - Absorption and Digestion" "HPA011897: " "unprognostic (1.05e-1)" "unprognostic (1.09e-1)" "unprognostic (1.56e-2)" "unprognostic (4.22e-2)" "unprognostic (3.71e-1)" "unprognostic (5.71e-3)" "unprognostic (4.83e-2)" "unprognostic (1.04e-1)" SIAE "CSE-C, LSE, MGC87009, YSG2" ENSG00000110013 "Sialic acid acetylesterase" Q9HAT2 11 124633113-124695707 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 98.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 92.2;Colonocytes: 107.7;Epicardial cells: 97.8;Platelets: 108.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 7.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Spleen - Fibroblasts_1, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038052, HPA038053" Approved "Intracellular and membrane" Enzyme NA NA 1400000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 76: Non-specific - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 2 "HPA038052: , HPA038053: " "unprognostic (1.50e-1)" "unprognostic (2.27e-2)" "unprognostic (1.87e-1)" "unprognostic (2.88e-3)" "unprognostic (1.17e-2)" "unprognostic (5.51e-2)" "unprognostic (1.77e-2)" "unprognostic (7.69e-3)" "unprognostic (7.07e-2)" "unprognostic (2.89e-2)" "potential prognostic favorable (7.35e-9)" "unprognostic (7.48e-2)" "potential prognostic favorable (1.03e-5)" "unprognostic (4.13e-1)" "unprognostic (1.05e-2)" "unprognostic (5.00e-2)" "unprognostic (2.42e-1)" "unprognostic (2.33e-2)" "unprognostic (8.78e-2)" "unprognostic (9.64e-2)" "unprognostic (4.98e-2)" "unprognostic (3.41e-2)" "unprognostic (1.61e-1)" "unprognostic (1.35e-1)" "unprognostic (3.14e-2)" "unprognostic (5.65e-3)" "unprognostic (8.18e-2)" "unprognostic (2.06e-1)" "unprognostic (2.25e-1)" "unprognostic (2.65e-1)" "unprognostic (4.56e-3)" SIAH1 hSIAH1 ENSG00000196470 "Siah E3 ubiquitin protein ligase 1" Q8IUQ4 16 48356364-48448402 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Apoptosis, Cell cycle, Differentiation, Spermatogenesis, Ubl conjugation pathway" "Developmental protein, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 301.7;Early spermatids: 286.6;Syncytiotrophoblasts: 1086.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB018724 Enhanced Uncertain Nucleoplasm,Mitochondria NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 55: Non-specific - Transcription" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 161 Mitochondria Nucleoplasm "CAB018724: " "unprognostic (4.55e-2)" "unprognostic (5.72e-3)" "unprognostic (1.30e-1)" "unprognostic (3.98e-3)" "unprognostic (2.61e-1)" "unprognostic (6.39e-2)" "unprognostic (8.78e-2)" "unprognostic (2.01e-3)" "unprognostic (3.88e-2)" "unprognostic (2.61e-1)" "potential prognostic favorable (2.41e-4)" "unprognostic (2.55e-2)" "unprognostic (3.04e-1)" "potential prognostic unfavorable (1.30e-4)" "unprognostic (5.36e-2)" "unprognostic (8.83e-2)" "unprognostic (4.91e-2)" "unprognostic (6.15e-2)" "unprognostic (4.19e-1)" "unprognostic (5.36e-2)" "unprognostic (1.87e-2)" "unprognostic (2.20e-1)" "unprognostic (4.79e-2)" "unprognostic (1.96e-2)" "unprognostic (9.99e-3)" "unprognostic (4.74e-2)" "unprognostic (5.31e-3)" "unprognostic (1.18e-3)" "unprognostic (4.12e-1)" "unprognostic (4.72e-2)" "unprognostic (6.52e-2)" SIAH2 ENSG00000181788 "Siah E3 ubiquitin protein ligase 2" O43255 3 150741125-150763477 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Apoptosis, Biological rhythms, Cell cycle, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 355.9;Cytotrophoblasts: 274.3;Esophageal apical cells: 350.8;Kupffer cells: 335.1;Megakaryocyte-Erythroid progenitors: 266.3;Platelets: 286.7;Syncytiotrophoblasts: 471.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA061293, CAB069930" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 76: Non-specific - Metabolism" "Cluster 34: Non-specific - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 47 Nucleoplasm Vesicles "CAB069930: , HPA061293: " "unprognostic (1.19e-2)" "unprognostic (1.86e-2)" "unprognostic (2.07e-1)" "unprognostic (1.78e-2)" "unprognostic (9.02e-2)" "unprognostic (5.29e-2)" "unprognostic (2.92e-1)" "unprognostic (9.37e-2)" "unprognostic (8.26e-2)" "unprognostic (2.04e-2)" "potential prognostic favorable (7.37e-4)" "unprognostic (5.18e-2)" "unprognostic (1.47e-1)" "unprognostic (2.83e-2)" "unprognostic (1.39e-1)" "unprognostic (4.33e-3)" "potential prognostic unfavorable (1.81e-4)" "potential prognostic favorable (2.56e-4)" "unprognostic (2.41e-2)" "unprognostic (2.81e-1)" "unprognostic (5.90e-2)" "potential prognostic unfavorable (3.31e-4)" "unprognostic (5.39e-2)" "unprognostic (6.94e-2)" "unprognostic (1.66e-1)" "unprognostic (2.99e-1)" "unprognostic (5.30e-2)" "unprognostic (1.16e-1)" "unprognostic (1.73e-1)" "unprognostic (1.04e-1)" "unprognostic (9.68e-2)" SIAH3 FLJ39203 ENSG00000215475 "Siah E3 ubiquitin protein ligase family member 3" Q8IW03 13 45777242-45851753 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.8;fallopian tube: 2.9;retina: 1.1" "Cell type enhanced" "Detected in some" "Brain inhibitory neurons: 39.5;Endometrial ciliated cells: 71.8;Ependymal cells: 16.4;Epididymal efferent duct ciliated cells: 21.8;Fallopian tube ciliated cells: 49.7;Loop of henle epithelial cells: 40.2;Other brain neurons: 31.6;Respiratory ciliated cells: 25.9;Retinal amacrine cells: 31.3;Retinal bipolar cells: 14.4;Retinal ganglion cells: 23.2" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 190.9;MGE interneuron: 103.5" "Cancer enhanced" "Detected in single" "Ovary Serous Cystadenocarcinoma (TCGA): 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Bone cancer: 2.8" "Adipose visceral - Mesothelial cells, Lung - Respiratory ciliated cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA060576 Uncertain Supported Nucleoplasm,Mitochondria NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 2 Mitochondria Nucleoplasm "HPA060576: " "unprognostic (4.33e-2)" "unprognostic (1.83e-1)" SIDT1 "FLJ20174, SID-1" ENSG00000072858 "SID1 transmembrane family member 1" Q9NXL6 3 113532555-113629575 "Predicted membrane proteins, Transporters" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.6;salivary gland: 10.2" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 138.3;B-cells: 179.0;Brain excitatory neurons: 132.5;Goblet cells: 217.4;Neuroendocrine cells: 147.5;NK-cells: 189.6;Somatotrophs: 131.3;T-cells: 134.0;Thymocytes: 138.9;Thyrotrophs: 209.6" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 12.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 33.7" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "breast cancer: 6.2;Myeloma: 7.2" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - Adrenal medulla cells, Breast - Breast glandular cells, Spleen - B-cells (Spleen), Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA035862 Approved NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 14: Neurons - Synaptic function" "Cluster 55: Lymphoma - Immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" "HPA035862: " "unprognostic (4.68e-3)" "unprognostic (3.12e-1)" "unprognostic (1.95e-1)" "unprognostic (4.31e-3)" "unprognostic (7.44e-2)" "unprognostic (1.90e-2)" "unprognostic (2.95e-1)" "unprognostic (9.70e-2)" "unprognostic (5.31e-3)" "unprognostic (1.44e-2)" "unprognostic (4.23e-2)" "unprognostic (2.40e-1)" "unprognostic (5.35e-3)" "unprognostic (2.20e-2)" "unprognostic (1.06e-1)" "unprognostic (1.97e-1)" "unprognostic (3.32e-1)" "unprognostic (1.16e-1)" "unprognostic (2.19e-3)" "unprognostic (1.23e-2)" "unprognostic (2.59e-1)" "unprognostic (1.26e-1)" SIDT2 CGI-40 ENSG00000149577 "SID1 transmembrane family member 2" Q8NBJ9 11 117178736-117197445 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Goblet cells: 84.8;Kupffer cells: 94.3;Pancreatic acinar cells: 96.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "intermediate monocyte: 83.6;non-classical monocyte: 152.0" "Lineage enriched" "Detected in all" 7 "monocytes: 152.0" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Minor Salivary Gland - Smooth muscle cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052352 Approved NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 8: Pancreas - Proteolysis" "Cluster 30: White matter - Myelination" "Cluster 5: Rhabdoid - Unknown function" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" "HPA052352: " "unprognostic (6.57e-2)" "unprognostic (1.32e-1)" "unprognostic (2.14e-1)" "unprognostic (4.36e-2)" "unprognostic (3.44e-1)" "unprognostic (7.56e-2)" "unprognostic (5.97e-2)" "unprognostic (8.55e-2)" "unprognostic (2.68e-1)" "unprognostic (4.10e-3)" "unprognostic (6.39e-2)" "unprognostic (5.67e-2)" "unprognostic (5.12e-2)" "unprognostic (1.03e-1)" "unprognostic (5.25e-2)" "unprognostic (4.13e-2)" "unprognostic (2.12e-1)" "unprognostic (1.65e-1)" "unprognostic (1.78e-1)" "unprognostic (4.29e-2)" "unprognostic (1.70e-1)" "unprognostic (1.55e-3)" "unprognostic (1.18e-1)" "unprognostic (9.04e-2)" "unprognostic (7.23e-2)" "unprognostic (2.41e-3)" "unprognostic (9.84e-2)" "unprognostic (1.63e-1)" "unprognostic (8.99e-2)" "unprognostic (1.18e-1)" "unprognostic (9.92e-2)" SIGIRR "IL-1R8, TIR8" ENSG00000185187 "Single Ig and TIR domain containing" Q6IA17 11 405716-417455 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 450.6;Melanocytes: 150.9" "Cell type enhanced" "Detected in many" "leukocyte: 79.6;lower rhombic lip: 90.8;pericyte: 77.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023188 Approved Approved "Nucleoli fibrillar center,Cytosol" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 70: Non-specific - Protein processing" "Cluster 49: Hindbrain - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 93: Hepatocytes - Bile production & excretion" 2 "Nucleoli fibrillar center, Cytosol" "HPA023188: " "unprognostic (5.84e-2)" "unprognostic (3.50e-2)" "unprognostic (2.36e-3)" "unprognostic (2.55e-2)" "unprognostic (1.90e-1)" "unprognostic (1.26e-2)" "potential prognostic unfavorable (3.42e-4)" "unprognostic (8.19e-2)" "unprognostic (3.74e-2)" "unprognostic (1.30e-1)" "unprognostic (3.35e-3)" "unprognostic (3.95e-2)" "potential prognostic favorable (6.80e-4)" "unprognostic (1.29e-1)" "unprognostic (3.24e-1)" "unprognostic (1.41e-2)" "unprognostic (4.18e-1)" "unprognostic (8.75e-2)" "unprognostic (1.10e-1)" "unprognostic (2.76e-1)" "unprognostic (2.32e-2)" "unprognostic (1.40e-2)" "unprognostic (5.17e-2)" "unprognostic (9.23e-3)" "unprognostic (2.62e-1)" "unprognostic (8.13e-2)" "unprognostic (3.62e-2)" "unprognostic (2.10e-3)" "unprognostic (2.17e-1)" "unprognostic (3.48e-2)" "unprognostic (1.63e-1)" SIGLEC1 "CD169, dJ1009E24.1, FLJ00051, FLJ00055, FLJ00073, FLJ32150, sialoadhesin, SIGLEC-1, SN" ENSG00000088827 "Sialic acid binding Ig like lectin 1" Q9BZZ2 20 3686970-3712600 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Endocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 10 "Hofbauer cells: 226.6;Kupffer cells: 296.2;Macrophages: 119.9" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 22.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "classical monocyte: 1.5" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid gland - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA053457 Supported "Intracellular and membrane" "Cell adhesion" NA NA 110000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" "HPA053457: " "unprognostic (2.60e-2)" "unprognostic (8.60e-2)" "unprognostic (5.67e-2)" "unprognostic (3.13e-2)" "unprognostic (6.83e-3)" "unprognostic (9.62e-2)" "unprognostic (2.80e-2)" "unprognostic (2.83e-1)" "unprognostic (2.28e-1)" "unprognostic (1.66e-1)" "unprognostic (9.36e-3)" "unprognostic (2.09e-1)" "unprognostic (1.40e-1)" "unprognostic (8.82e-2)" "unprognostic (7.82e-2)" "unprognostic (3.62e-2)" "unprognostic (9.58e-3)" "unprognostic (1.12e-1)" "unprognostic (1.64e-1)" "unprognostic (1.38e-1)" "unprognostic (2.66e-2)" "unprognostic (1.02e-1)" "unprognostic (6.14e-3)" "unprognostic (1.11e-1)" "unprognostic (9.14e-2)" "unprognostic (8.84e-2)" "unprognostic (1.22e-1)" "potential prognostic unfavorable (1.24e-4)" "unprognostic (1.27e-1)" "unprognostic (4.74e-3)" SIGLEC10 "MGC126774, PRO940, SIGLEC-10, SLG2" ENSG00000142512 "Sialic acid binding Ig like lectin 10" Q96LC7 19 51410020-51417803 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Cell adhesion, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 45.5" "Cell type enhanced" "Detected in some" "B-cells: 21.8;cDC: 27.4;Kupffer cells: 139.4;Macrophages: 67.4;Mast cells: 15.7;Microglia: 54.9;Monocyte progenitors: 18.6;monocytes: 76.1;Neutrophils: 63.8" "Cell type enriched" "Detected in some" 6 "central nervous system macrophage: 69.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "eosinophil: 767.4;intermediate monocyte: 252.2;non-classical monocyte: 542.7" "Group enriched" "Detected in many" 16 "granulocytes: 767.4;monocytes: 542.7" "Group enriched" "Detected in many" 6 "Leukemia: 10.6;lymphoma: 31.2" "Adrenal gland - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Pancreas - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Skin - Inner root sheath cells, Stomach - Macrophages, Thyroid gland - Macrophages" "CAB025807, HPA027093" Enhanced Supported "Plasma membrane,Actin filaments,Cytosol" "Intracellular and membrane" Immunity NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 30: White matter - Myelination" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" Cytosol "Plasma membrane, Actin filaments" "CAB025807: , HPA027093: " "unprognostic (2.88e-2)" "unprognostic (6.70e-2)" "unprognostic (1.70e-1)" "unprognostic (1.12e-2)" "unprognostic (2.44e-1)" "unprognostic (4.89e-2)" "unprognostic (1.14e-2)" "unprognostic (2.87e-2)" "unprognostic (4.45e-2)" "unprognostic (1.27e-1)" "unprognostic (5.38e-2)" "unprognostic (1.64e-1)" "unprognostic (6.60e-2)" "unprognostic (4.26e-2)" "unprognostic (5.13e-2)" "unprognostic (1.08e-1)" "unprognostic (1.39e-1)" "unprognostic (8.96e-2)" "unprognostic (2.28e-1)" "unprognostic (2.51e-1)" "unprognostic (5.03e-1)" "unprognostic (1.66e-1)" "unprognostic (1.61e-3)" "unprognostic (2.69e-1)" "unprognostic (1.34e-1)" "unprognostic (1.55e-1)" "unprognostic (3.62e-1)" "unprognostic (2.08e-1)" "unprognostic (1.13e-2)" "unprognostic (3.51e-1)" "unprognostic (1.82e-1)" SIGLEC11 ENSG00000161640 "Sialic acid binding Ig like lectin 11" Q96RL6 19 49948985-49961172 "Essential proteins, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "lymphoid tissue: 21.7;ovary: 52.6" "Cell type enriched" "Detected in some" 5 "Microglia: 29.8" "Cell type enriched" "Detected in single" 50 "central nervous system macrophage: 34.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 1.4;non-classical monocyte: 1.3" "Group enriched" "Detected in many" 7 "granulocytes: 1.4;monocytes: 1.3" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Parietal cells" "HPA052132, HPA060278" Approved Uncertain "Nucleoplasm,Golgi apparatus" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" "Golgi apparatus" Nucleoplasm "HPA052132: , HPA060278: " "unprognostic (1.38e-1)" "unprognostic (5.78e-2)" "unprognostic (1.40e-1)" "unprognostic (2.01e-1)" "unprognostic (2.36e-1)" "potential prognostic favorable (9.98e-4)" "potential prognostic favorable (3.13e-4)" "unprognostic (4.06e-2)" SIGLEC12 "S2V, Siglec-12, Siglec-L1, Siglec-XII, SIGLECL1, SLG" ENSG00000254521 "Sialic acid binding Ig like lectin 12" Q96PQ1 19 51491227-51501800 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 4.3;lymphoid tissue: 16.1" "Cell type enhanced" "Detected in some" "cDC: 2.0;Hofbauer cells: 4.8;Kupffer cells: 6.1;Macrophages: 10.5;Mast cells: 3.6;Monocyte progenitors: 3.2;monocytes: 9.3;Neutrophils: 1.8;Platelets: 1.4" "Cell type enhanced" "Detected in single" "central nervous system macrophage: 1.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 48 "Leukemia: 17.5" "Kidney - Macrophages, Prostate - Macrophages" NA NA "Cluster 66: Lymphoid tissue - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 11 "unprognostic (1.66e-1)" "unprognostic (1.46e-1)" "unprognostic (1.67e-1)" "unprognostic (1.15e-1)" "unprognostic (2.55e-1)" "unprognostic (1.35e-1)" "unprognostic (7.14e-2)" "unprognostic (1.06e-1)" "unprognostic (6.62e-2)" "unprognostic (1.61e-2)" "unprognostic (7.63e-2)" "unprognostic (1.09e-2)" "unprognostic (1.79e-2)" "unprognostic (9.43e-2)" "unprognostic (6.87e-2)" "unprognostic (1.38e-1)" "unprognostic (4.50e-2)" SIGLEC14 ENSG00000254415 "Sialic acid binding Ig like lectin 14" Q08ET2 19 51639478-51646825 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 22.0;lymphoid tissue: 21.0" "Cell type enhanced" "Detected in some" "cDC: 1.1;Kupffer cells: 4.1;Macrophages: 1.2;Monocyte progenitors: 1.0;monocytes: 1.8;Neutrophil progenitors: 1.0;Neutrophils: 8.9" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 57.8;intermediate monocyte: 71.1;myeloid DC: 34.7;neutrophil: 80.0;non-classical monocyte: 58.8" "Group enriched" "Detected in many" 5 "dendritic cells: 34.7;granulocytes: 80.0;monocytes: 71.1" "Cancer enhanced" "Detected in single" "Leukemia: 3.2" "Adipose subcutaneous - Macrophages, Adrenal gland - Macrophages, Colon - Macrophages, Kidney - Macrophages, Pancreas - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid gland - Macrophages" "HPA014377, HPA014428" Uncertain Uncertain "Vesicles,Plasma membrane" NA NA 9700000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" Vesicles "Plasma membrane" "HPA014377: , HPA014428: " "unprognostic (1.77e-3)" "unprognostic (9.34e-2)" "unprognostic (1.13e-1)" "unprognostic (2.51e-1)" "unprognostic (4.69e-3)" "unprognostic (1.70e-1)" "unprognostic (5.12e-3)" "unprognostic (1.90e-1)" "unprognostic (7.86e-3)" "unprognostic (3.25e-1)" "unprognostic (2.51e-2)" "unprognostic (2.11e-3)" "unprognostic (9.99e-2)" "unprognostic (5.02e-1)" "unprognostic (5.31e-2)" "unprognostic (9.59e-3)" "unprognostic (6.81e-2)" "unprognostic (2.32e-1)" "unprognostic (3.46e-1)" "unprognostic (1.74e-1)" "unprognostic (2.44e-2)" "unprognostic (1.16e-1)" "unprognostic (1.88e-3)" "unprognostic (8.73e-2)" "unprognostic (2.28e-2)" "unprognostic (2.99e-1)" "unprognostic (3.95e-2)" "unprognostic (9.73e-2)" "unprognostic (1.93e-1)" SIGLEC15 "CD33L3, HsT1361" ENSG00000197046 "Sialic acid binding Ig like lectin 15" Q6ZMC9 18 45825675-45844094 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 1.6;intestine: 2.8;urinary bladder: 1.2" "Cell type enhanced" "Detected in some" "Breast hormone-responsive cells: 6.6;Cardiomyocytes: 3.3;Endometrial secretory cells: 3.2;Epicardial cells: 4.5;Fallopian tube ciliated cells: 3.3;Hofbauer cells: 18.2;Parietal cells: 12.4;Urothelial cells: 5.0" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 6 "classical monocyte: 3.0;myeloid DC: 1.0" "Group enriched" "Detected in many" 21 "dendritic cells: 1.0;monocytes: 3.0" "Cancer enhanced" "Detected in many" "Brain cancer: 11.3;thyroid cancer: 12.9" "Liver - Hepatocytes, Skin - Eccrine sweat gland cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA053509 Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 15: Non-specific - Transcription" "Cluster 72: Neuronal - Signal transduction" "Cluster 97: Non-specific - Cellular respiration" "Nucleoplasm, Golgi apparatus" "HPA053509: " "unprognostic (9.75e-2)" "unprognostic (4.17e-2)" "unprognostic (5.98e-2)" "unprognostic (8.34e-3)" "unprognostic (5.77e-3)" "unprognostic (1.79e-1)" "unprognostic (1.35e-2)" "unprognostic (1.44e-1)" "unprognostic (1.62e-2)" "unprognostic (5.27e-2)" "unprognostic (6.17e-1)" SIGLEC16 "Siglec-P16, SIGLECP16" ENSG00000161643 "Sialic acid binding Ig like lectin 16" 19 49969600-49975819 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 10 "lymphoid tissue: 6.1;ovary: 21.7" "Cell type enhanced" "Detected in some" "Hofbauer cells: 3.9;Kupffer cells: 24.6;Late spermatids: 18.5;Macrophages: 7.7;Microglia: 4.7;monocytes: 10.5;Oocytes: 4.6;Ovarian stromal cells: 15.3" "Group enriched" "Detected in some" 12 "central nervous system macrophage: 5.3;leukocyte: 1.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.9" "Group enriched" "Detected in many" 11 "granulocytes: 1.3;monocytes: 2.9" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Prostate - Macrophages, Skeletal muscle - Macrophages, Spleen - Macrophages" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" SIGLEC5 "CD170, CD33L2, OB-BP2, SIGLEC-5" ENSG00000268500 "Sialic acid binding Ig like lectin 5" O15389 19 51610960-51630401 "CD markers, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "bone marrow: 27.6;lymphoid tissue: 12.1" "Group enriched" "Detected in some" 10 "Neutrophil progenitors: 133.1;Neutrophils: 424.2" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 12 "Bladder Urothelial Carcinoma (TCGA): 26.7" "Region enhanced" "Detected in many" "cerebral cortex: 9.5" "Group enriched" "Detected in many" 4 "neutrophil: 284.6;non-classical monocyte: 96.2" "Group enriched" "Detected in many" 6 "granulocytes: 284.6;monocytes: 96.2" "Group enriched" "Detected in some" 7 "Leukemia: 6.0;lymphoma: 1.6" "Adipose visceral - Neutrophils, Kidney - Macrophages, Liver - Neutrophils, Lung - Neutrophils_2, Spleen - Neutrophils_2" HPA009085 Approved NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 15: Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 49: HMC-1 - Innate immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 7 "HPA009085: " "unprognostic (1.65e-1)" "unprognostic (1.70e-1)" "unprognostic (1.13e-1)" "unprognostic (2.39e-1)" "unprognostic (5.98e-2)" "unprognostic (1.73e-1)" "unprognostic (1.94e-2)" SIGLEC6 "CD327, CD33L, CD33L1, OB-BP1, SIGLEC-6" ENSG00000105492 "Sialic acid binding Ig like lectin 6" O43699 19 51517819-51531856 "CD markers, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 24 "placenta: 100.4" "Group enriched" "Detected in some" 16 "Cytotrophoblasts: 204.1;Mast cells: 197.5;Migrating cytotrophoblasts: 227.7;Syncytiotrophoblasts: 427.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bladder Urothelial Carcinoma (TCGA): 2.8;Thyroid Carcinoma (TCGA): 7.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 7.2;plasmacytoid DC: 11.0" "Group enriched" "Detected in many" 9 "B-cells: 7.2;dendritic cells: 11.0;granulocytes: 4.9" "Group enriched" "Detected in some" 5 "Bladder cancer: 7.8;colorectal cancer: 11.8;Leukemia: 25.0" "Adipose subcutaneous - Mast cells, Adipose visceral - Mast cells, Colon - Mast cells, Lung - Mast cells, Minor Salivary Gland - Mast cells, Prostate - Fibroblasts, Skin - Mast cells" "Low region specificity" "Detected in some" "HPA008945, HPA009084, HPA018198" Enhanced Approved "Plasma membrane,Cytosol" "Secreted to blood" "Cell adhesion" NA NA 8000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 48: Non-specific - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 2 "Plasma membrane, Cytosol" "HPA008945: , HPA009084: , HPA018198: " "unprognostic (6.51e-2)" "unprognostic (5.75e-2)" "unprognostic (1.42e-1)" "potential prognostic favorable (1.21e-4)" "unprognostic (4.50e-2)" "unprognostic (1.16e-1)" "unprognostic (1.54e-1)" "unprognostic (1.51e-1)" "unprognostic (1.69e-2)" "unprognostic (1.32e-2)" "unprognostic (4.26e-2)" SIGLEC7 "CD328, p75/AIRM1, QA79, SIGLEC-7, SIGLEC19P, SIGLECP2" ENSG00000168995 "Sialic acid binding Ig like lectin 7" Q9Y286 19 51142299-51153526 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 18.2" "Cell type enhanced" "Detected in some" "cDC: 10.0;Hofbauer cells: 27.4;Innate lymphoid cells: 13.6;Kupffer cells: 91.2;Macrophages: 24.1;monocytes: 30.2;Neutrophils: 11.9;NK-cells: 17.4;Platelets: 8.4" "Group enriched" "Detected in some" 18 "central nervous system macrophage: 5.2;leukocyte: 7.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 242.7" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 16 "Leukemia: 3.5;Myeloma: 4.5" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Lung - Macrophages, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Spleen - Macrophages, Stomach - Macrophages, Thyroid gland - Macrophages" "HPA075513, CAB080396" Enhanced Approved "Vesicles,Plasma membrane" "Intracellular and membrane" "Cell adhesion" NA NA 80000 "Cluster 25: Non-specific - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 1 "Plasma membrane" Vesicles "CAB080396: , HPA075513: " "unprognostic (2.87e-2)" "unprognostic (6.43e-2)" "unprognostic (1.34e-1)" "unprognostic (1.93e-3)" "unprognostic (1.70e-1)" "unprognostic (8.10e-2)" "unprognostic (1.21e-2)" "unprognostic (3.39e-1)" "unprognostic (2.19e-1)" "unprognostic (5.24e-2)" "unprognostic (1.28e-1)" "unprognostic (4.53e-1)" "unprognostic (9.60e-2)" "unprognostic (2.08e-1)" "unprognostic (3.33e-2)" "unprognostic (4.38e-2)" "potential prognostic unfavorable (8.95e-4)" "unprognostic (4.36e-2)" "unprognostic (8.85e-2)" "unprognostic (3.48e-2)" "unprognostic (4.22e-1)" "unprognostic (1.13e-1)" "unprognostic (5.22e-2)" "unprognostic (9.99e-2)" "unprognostic (9.29e-2)" "unprognostic (3.53e-2)" "unprognostic (4.19e-2)" "unprognostic (1.14e-3)" "unprognostic (2.92e-1)" "unprognostic (2.18e-1)" SIGLEC8 "MGC59785, SAF2, SIGLEC-8, SIGLEC8L" ENSG00000105366 "Sialic acid binding Ig like lectin 8" Q9NYZ4 19 51450847-51458456 "CD markers, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.8;lymphoid tissue: 6.4" "Cell type enhanced" "Detected in some" "Kupffer cells: 38.9;Macrophages: 12.3;Mast cells: 32.0;Microglia: 57.4" "Cell type enriched" "Detected in some" 55 "central nervous system macrophage: 66.2" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 12.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 38 "eosinophil: 290.9" "Lineage enriched" "Detected in single" 706 "granulocytes: 290.9" "Cancer enriched" "Detected in single" 7 "Leukemia: 2.4" "Adipose subcutaneous - Mast cells, Adrenal gland - Macrophages, Colon - Mast cells, Pituitary gland - Macrophages, Skin - Mast cells, Spleen - Macrophages, Stomach - T-cells" HPA012556 Uncertain Uncertain Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 1 Cytosol "HPA012556: " "unprognostic (7.62e-2)" "unprognostic (9.23e-2)" "unprognostic (2.35e-2)" "unprognostic (2.60e-1)" "unprognostic (3.50e-3)" "unprognostic (3.35e-1)" "potential prognostic favorable (9.39e-4)" "unprognostic (4.97e-3)" "unprognostic (2.25e-3)" "unprognostic (2.31e-3)" "unprognostic (4.63e-2)" "unprognostic (3.04e-1)" "unprognostic (2.72e-1)" "unprognostic (2.92e-1)" "unprognostic (2.52e-1)" "unprognostic (1.90e-3)" "unprognostic (1.97e-2)" "unprognostic (2.11e-1)" SIGLEC9 CD329 ENSG00000129450 "Sialic acid binding Ig like lectin 9" Q9Y336 19 51124906-51136651 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 19.9" "Cell type enhanced" "Detected in some" "cDC: 31.6;Hofbauer cells: 60.0;Kupffer cells: 86.1;Macrophages: 46.4;Microglia: 21.8;Monocyte progenitors: 39.1;monocytes: 92.6;Neutrophil progenitors: 18.5;Neutrophils: 226.9" "Group enriched" "Detected in some" 30 "central nervous system macrophage: 27.6;leukocyte: 10.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "classical monocyte: 199.2;intermediate monocyte: 182.7;myeloid DC: 169.3;neutrophil: 212.9;non-classical monocyte: 122.4" "Group enriched" "Detected in many" 13 "dendritic cells: 169.3;granulocytes: 212.9;monocytes: 199.2" "Group enriched" "Detected in some" 7 "Leukemia: 1.9;Myeloma: 3.1" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Thyroid gland - Macrophages" "HPA010682, CAB080397" Approved NA NA 260000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 24: Neutrophils - Innate immunity signal integration" 4 "CAB080397: , HPA010682: " "unprognostic (2.51e-1)" "unprognostic (3.67e-1)" "unprognostic (3.09e-1)" "unprognostic (6.12e-2)" "unprognostic (9.25e-2)" "unprognostic (6.35e-2)" "unprognostic (7.61e-3)" "unprognostic (2.29e-1)" "unprognostic (1.20e-1)" "unprognostic (1.81e-1)" "unprognostic (1.83e-1)" "unprognostic (3.09e-1)" "unprognostic (1.42e-2)" "unprognostic (3.41e-2)" "unprognostic (3.70e-3)" "unprognostic (3.78e-2)" "unprognostic (2.82e-3)" "unprognostic (3.50e-2)" "unprognostic (1.40e-1)" "unprognostic (3.78e-3)" "unprognostic (4.02e-1)" "unprognostic (7.90e-2)" "unprognostic (3.05e-2)" "unprognostic (1.20e-2)" "unprognostic (1.75e-1)" "unprognostic (2.24e-2)" "unprognostic (1.03e-1)" "unprognostic (1.68e-2)" "unprognostic (4.73e-1)" "unprognostic (1.99e-1)" SIGLECL1 "C19orf75, FLJ40235, SIGLEC23P, SIGLECP7" ENSG00000179213 "SIGLEC family like 1" Q8N7X8 19 51246348-51269330 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 66 "testis: 19.0" "Cell type enhanced" "Detected in some" "Early primary spermatocytes: 40.0;Early spermatids: 34.1;Late primary spermatocytes: 140.6;Late spermatids: 121.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lymphoma: 1.1" "Testis - Early spermatids" HPA079471 Enhanced NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 50: Lymphoma - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 22 "HPA079471: " SIGMAR1 "OPRS1, SR-BP1" ENSG00000147955 "Sigma non-opioid intracellular receptor 1" Q99720 9 34634722-34637844 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Receptor "Amyotrophic lateral sclerosis, Disease variant, FDA approved drug targets, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 167.8" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 96.4;Extravillous trophoblasts: 111.9;Hepatocytes: 108.2;Migrating cytotrophoblasts: 84.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013470, HPA018002, HPA024071" Enhanced NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Cell proliferation" 8 "CAB013470: , HPA018002: , HPA024071: " "unprognostic (1.39e-2)" "unprognostic (6.53e-2)" "unprognostic (1.20e-1)" "unprognostic (1.33e-1)" "unprognostic (1.74e-1)" "unprognostic (6.70e-3)" "unprognostic (1.37e-1)" "unprognostic (2.42e-1)" "unprognostic (1.35e-2)" "unprognostic (5.11e-2)" "potential prognostic favorable (9.46e-4)" "unprognostic (5.05e-2)" "unprognostic (3.97e-2)" "unprognostic (1.36e-2)" "unprognostic (1.61e-2)" "unprognostic (1.46e-3)" "potential prognostic unfavorable (1.92e-5)" "unprognostic (1.98e-1)" "unprognostic (1.03e-1)" "unprognostic (4.29e-3)" "unprognostic (9.02e-2)" "unprognostic (1.13e-2)" "unprognostic (1.32e-1)" "unprognostic (8.75e-2)" "unprognostic (4.41e-2)" "unprognostic (1.38e-1)" "unprognostic (4.55e-2)" "unprognostic (2.52e-2)" "unprognostic (3.11e-1)" "unprognostic (4.96e-2)" "unprognostic (3.36e-1)" SIK1 "msk, SNF1LK" ENSG00000142178 "Salt inducible kinase 1" P57059 21 43414483-43427131 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms, Cell cycle, Differentiation" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Epilepsy, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 14.5;Endometrial glandular cells: 10.1;Endometrial luminal cells: 5.9;Medullary thymic epithelial cells: 7.2;Papillary tip epithelial cells: 8.2;Suprabasal keratinocytes: 29.4" "Cell type enhanced" "Detected in some" "endothelial cell: 1.3;vascular associated smooth muscle cell: 1.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 2.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB023801, HPA038211, HPA078064" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 58: Skin - Keratinization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 7: Liver cancer - Metabolism" "Cluster 26: Keratinocytes - Keratinization" 41 Nucleoplasm Vesicles "CAB023801: , HPA038211: , HPA078064: " "unprognostic (3.29e-1)" "unprognostic (8.13e-2)" "unprognostic (3.19e-1)" "unprognostic (1.22e-1)" "unprognostic (2.24e-2)" "unprognostic (1.62e-1)" "unprognostic (1.27e-1)" "unprognostic (7.58e-2)" "unprognostic (3.60e-2)" "unprognostic (1.94e-1)" "unprognostic (7.30e-2)" "unprognostic (2.84e-1)" "unprognostic (2.89e-1)" "unprognostic (3.39e-1)" "unprognostic (1.09e-1)" "unprognostic (1.28e-1)" "unprognostic (3.26e-2)" "potential prognostic unfavorable (2.25e-4)" "unprognostic (7.29e-3)" "unprognostic (1.22e-1)" "unprognostic (1.32e-1)" "unprognostic (1.06e-2)" "unprognostic (2.76e-2)" "unprognostic (2.42e-1)" "unprognostic (1.13e-2)" "unprognostic (2.57e-2)" "unprognostic (9.66e-2)" "unprognostic (1.27e-1)" "unprognostic (5.32e-2)" "unprognostic (4.98e-1)" "unprognostic (2.92e-1)" SIK2 "DKFZp434K1115, KIAA0781, LOH11CR1I, QIK, SNF1LK2" ENSG00000170145 "Salt inducible kinase 2" Q9H0K1 11 111602449-111730855 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 1896.4;Lactotrophs: 942.5;Salivary acinar cells: 802.5;Somatotrophs: 1639.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016026, HPA071049" Approved Approved "Nucleoplasm,Nuclear speckles,Vesicles,Intermediate filaments,Cytosol" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 53: Neurons - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 89: Adipocytes - Lipid metabolism" 25 "Nucleoplasm, Vesicles" "Nuclear speckles, Intermediate filaments, Cytosol" "HPA016026: , HPA071049: " "unprognostic (7.61e-3)" "unprognostic (1.02e-1)" "unprognostic (7.05e-2)" "unprognostic (1.46e-1)" "unprognostic (3.06e-1)" "unprognostic (2.74e-2)" "unprognostic (4.82e-2)" "unprognostic (1.94e-1)" "unprognostic (4.48e-2)" "unprognostic (8.94e-3)" "validated prognostic favorable (3.25e-10)" "validated prognostic favorable (1.19e-4)" "unprognostic (9.36e-3)" "unprognostic (1.65e-3)" "unprognostic (1.33e-2)" "unprognostic (1.47e-1)" "unprognostic (1.55e-1)" "unprognostic (9.51e-2)" "unprognostic (1.45e-1)" "unprognostic (2.49e-3)" "unprognostic (1.31e-2)" "unprognostic (2.48e-2)" "unprognostic (2.23e-1)" "unprognostic (9.66e-2)" "unprognostic (1.00e-2)" "unprognostic (1.39e-1)" "unprognostic (4.13e-2)" "unprognostic (1.17e-1)" "unprognostic (5.19e-1)" "unprognostic (5.62e-2)" "unprognostic (9.30e-2)" SIK3 "FLJ12240, KIAA0999, L19, QSK" ENSG00000160584 "SIK family kinase 3" Q9Y2K2 11 116843402-117098437 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial luminal cells: 2137.8;Neutrophils: 3412.0;Oligodendrocytes: 2587.8" "Cell type enhanced" "Detected in all" "oligodendrocyte: 2857.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Pituitary gland - Undifferentiated cells (Pituitary gland), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045245, HPA048161" Enhanced NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 24: Non-specific - Unknown function" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 19 "HPA045245: , HPA048161: " "unprognostic (5.30e-2)" "unprognostic (1.36e-1)" "unprognostic (1.52e-2)" "unprognostic (1.92e-2)" "unprognostic (3.49e-2)" "unprognostic (1.72e-1)" "unprognostic (1.22e-1)" "unprognostic (3.83e-2)" "unprognostic (1.14e-1)" "unprognostic (2.60e-1)" "validated prognostic favorable (7.27e-7)" "validated prognostic favorable (3.98e-4)" "unprognostic (4.35e-2)" "unprognostic (9.28e-2)" "unprognostic (1.75e-2)" "unprognostic (6.91e-2)" "unprognostic (5.19e-3)" "unprognostic (3.43e-1)" "unprognostic (2.35e-1)" "unprognostic (1.28e-2)" "unprognostic (5.71e-2)" "unprognostic (2.41e-1)" "unprognostic (1.47e-3)" "unprognostic (4.15e-1)" "unprognostic (2.00e-2)" "unprognostic (2.41e-2)" "unprognostic (2.48e-1)" "unprognostic (1.12e-1)" "unprognostic (1.79e-1)" "unprognostic (1.01e-1)" "unprognostic (9.53e-2)" SIKE1 "FLJ21168, SIKE" ENSG00000052723 "Suppressor of IKBKE 1" Q9BRV8 1 114769479-114780685 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 116.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024177, HPA025726" Supported Approved "Vesicles,Focal adhesion sites" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 33 "Focal adhesion sites" Vesicles "HPA024177: , HPA025726: " "unprognostic (2.70e-2)" "unprognostic (5.09e-2)" "unprognostic (1.80e-1)" "unprognostic (8.06e-2)" "unprognostic (1.45e-1)" "unprognostic (2.18e-1)" "unprognostic (1.69e-1)" "unprognostic (8.87e-2)" "unprognostic (3.71e-2)" "unprognostic (5.46e-3)" "unprognostic (1.48e-3)" "unprognostic (6.82e-3)" "unprognostic (3.76e-1)" "unprognostic (5.55e-3)" "unprognostic (3.77e-2)" "unprognostic (1.94e-2)" "unprognostic (3.06e-2)" "unprognostic (4.94e-2)" "unprognostic (1.40e-1)" "unprognostic (1.31e-1)" "unprognostic (2.06e-1)" "unprognostic (2.01e-2)" "unprognostic (1.99e-2)" "unprognostic (7.71e-2)" "unprognostic (6.24e-3)" "unprognostic (3.45e-1)" "unprognostic (1.09e-2)" "unprognostic (1.09e-1)" "unprognostic (2.98e-1)" "potential prognostic unfavorable (8.35e-4)" "unprognostic (7.63e-2)" SIL1 "BAP, MSS, ULG5" ENSG00000120725 "SIL1 nucleotide exchange factor" Q9H173 5 138946724-139293557 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Translocation, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011949 Enhanced "Intracellular and membrane" Transport NA NA 770000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 70: Non-specific - Protein processing" "Cluster 36: Choroid plexus - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 8: Non-specific - Secretory pathway" 25 "HPA011949: " "unprognostic (8.63e-2)" "unprognostic (1.50e-2)" "unprognostic (4.43e-3)" "unprognostic (1.09e-1)" "unprognostic (1.98e-3)" "unprognostic (1.82e-1)" "unprognostic (6.73e-3)" "unprognostic (1.86e-2)" "potential prognostic unfavorable (5.99e-5)" "unprognostic (1.07e-2)" "unprognostic (1.06e-2)" "unprognostic (5.96e-2)" "unprognostic (3.98e-2)" "unprognostic (9.97e-2)" "unprognostic (6.18e-3)" "unprognostic (3.05e-2)" "unprognostic (2.42e-1)" "unprognostic (8.02e-2)" "unprognostic (5.15e-2)" "unprognostic (2.87e-1)" "unprognostic (8.68e-2)" "unprognostic (2.80e-1)" "unprognostic (1.79e-1)" "unprognostic (6.48e-2)" "unprognostic (2.83e-1)" "unprognostic (1.47e-1)" "unprognostic (8.64e-2)" "unprognostic (2.61e-1)" "unprognostic (4.68e-2)" "unprognostic (5.52e-2)" "unprognostic (5.70e-2)" SIM1 bHLHe14 ENSG00000112246 "SIM bHLH transcription factor 1" P81133 6 100385009-100464921 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 2.7;kidney: 9.2;skeletal muscle: 3.3" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 372.1;Epididymal basal cells: 51.8;Epididymal efferent duct absorptive cells: 63.9;Loop of henle epithelial cells: 285.8;Pancreatic islet cells: 92.9;Papillary tip epithelial cells: 68.4;Renal collecting duct intercalated cells: 265.8;Renal collecting duct principal cells: 160.3;Renal connecting tubule cells: 245.0" "Cell type enriched" "Detected in some" 6 "mammillary body: 89.4" "Group enriched" "Detected in some" 4 "Kidney Chromophobe (TCGA): 10.7;Kidney Renal Papillary Cell Carcinoma (TCGA): 3.3" "Group enriched" "Detected in some" 4 "hypothalamus: 9.2;midbrain: 2.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney cancer: 2.3;ovarian cancer: 1.9" "Testis - Early spermatids" "Region enriched" "Detected in single" 8 "hypothalamus: 5.2" "Low region specificity" "Detected in some" HPA024385 Approved "Nuclear speckles" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 5 "Nuclear speckles" "HPA024385: " "unprognostic (2.05e-1)" "unprognostic (2.08e-2)" "unprognostic (2.58e-3)" "unprognostic (1.19e-3)" "unprognostic (1.85e-2)" SIM2 "bHLHe15, MGC119447, SIM" ENSG00000159263 "SIM bHLH transcription factor 2" Q14190 21 36699115-36749917 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 29.1;kidney: 64.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 99.7;Basal prostatic cells: 47.2;Esophageal apical cells: 76.6;Esophageal basal cells: 88.5;Esophageal suprabasal cells: 59.9;Foveolar cells: 38.8;Gastric chief cells: 40.4;Loop of henle epithelial cells: 357.3;Mucous neck cells: 79.8;Myonuclei: 50.5;Prostatic glandular cells: 85.0;Submucosal glandular cells: 41.9;Suprabasal keratinocytes: 46.8" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Prostate Adenocarcinoma (TCGA): 36.1;Stomach Adenocarcinoma (TCGA): 13.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 38.6" "Kidney - Ascending Loop of Henle cells, Prostate - Prostate glandular cells, Testis - Late spermatids" "Not detected" "Not detected" "Region enhanced" "Detected in single" "hypothalamus: 1.8" HPA029295 Approved Supported "Nucleoplasm,Nuclear bodies" No No "Cluster 72: Kidney - Transmembrane transport" "Cluster 29: Forebrain - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 5 "Nucleoplasm, Nuclear bodies" "HPA029295: " "unprognostic (3.13e-2)" "potential prognostic unfavorable (1.44e-4)" "unprognostic (4.17e-1)" "potential prognostic favorable (5.67e-4)" "unprognostic (2.75e-2)" "unprognostic (1.28e-3)" "unprognostic (2.57e-1)" "unprognostic (1.72e-1)" "unprognostic (3.32e-2)" "unprognostic (6.08e-3)" "unprognostic (5.38e-2)" "unprognostic (1.30e-1)" "unprognostic (2.86e-2)" "unprognostic (2.32e-2)" "unprognostic (3.82e-2)" "unprognostic (1.20e-3)" "unprognostic (3.03e-1)" "unprognostic (8.79e-2)" "unprognostic (2.27e-2)" "unprognostic (8.53e-2)" "unprognostic (1.35e-2)" "unprognostic (9.76e-2)" "unprognostic (3.05e-1)" "unprognostic (9.92e-2)" SIMC1 "C5orf25, FLJ44216, OOMA1, PLEIAD" ENSG00000170085 "SUMO interacting motifs containing 1" Q8NDZ2 5 176238367-176345991 "Predicted intracellular proteins" "Protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 38.7" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 291.0;Sertoli cells: 185.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037889, HPA037890" Uncertain Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 75: Ovary - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 94: Gonadal somatic cells - Mixed function" 13 Nucleoplasm "Nucleoli fibrillar center" "HPA037889: , HPA037890: " "unprognostic (2.50e-3)" "unprognostic (1.64e-1)" "unprognostic (4.05e-2)" "unprognostic (6.61e-3)" "unprognostic (2.02e-1)" "potential prognostic unfavorable (2.99e-5)" "unprognostic (7.33e-2)" "unprognostic (3.82e-2)" "potential prognostic unfavorable (7.08e-5)" "unprognostic (3.08e-2)" "unprognostic (6.61e-2)" "unprognostic (1.19e-1)" "unprognostic (4.72e-2)" "unprognostic (3.80e-2)" "unprognostic (2.84e-1)" "unprognostic (1.11e-1)" "unprognostic (3.05e-1)" "unprognostic (2.76e-1)" "unprognostic (3.95e-1)" "unprognostic (4.38e-2)" "unprognostic (6.95e-2)" "unprognostic (2.20e-1)" "unprognostic (1.68e-2)" "unprognostic (4.09e-2)" "potential prognostic unfavorable (2.14e-4)" "unprognostic (9.12e-2)" "unprognostic (1.41e-1)" "unprognostic (5.11e-2)" "unprognostic (6.45e-2)" SIN3A "DKFZP434K2235, KIAA0700" ENSG00000169375 "SIN3 transcription regulator family member A" Q96ST3 15 75369379-75455842 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" Repressor "Cancer-related genes, Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 244.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004506, HPA047213, HPA062123" Enhanced Enhanced Nucleoplasm NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 39: Testis - Nuclear processes" "Cluster 15: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 149 Nucleoplasm "CAB004506: , HPA047213: , HPA062123: " "unprognostic (4.88e-2)" "unprognostic (1.73e-1)" "unprognostic (6.40e-2)" "unprognostic (4.31e-1)" "unprognostic (1.51e-1)" "unprognostic (1.36e-1)" "unprognostic (4.17e-1)" "unprognostic (3.95e-1)" "unprognostic (1.04e-1)" "unprognostic (1.81e-2)" "validated prognostic favorable (3.21e-5)" "validated prognostic favorable (8.33e-5)" "unprognostic (6.48e-2)" "potential prognostic unfavorable (4.33e-4)" "unprognostic (5.38e-3)" "unprognostic (6.69e-2)" "unprognostic (9.89e-2)" "unprognostic (1.83e-1)" "unprognostic (1.48e-2)" "unprognostic (1.12e-1)" "unprognostic (2.74e-1)" "unprognostic (6.92e-2)" "unprognostic (1.75e-2)" "unprognostic (2.80e-1)" "unprognostic (3.39e-2)" "unprognostic (1.65e-1)" "unprognostic (3.39e-1)" "unprognostic (3.00e-2)" "unprognostic (1.34e-1)" "unprognostic (4.67e-2)" "unprognostic (1.08e-1)" SIN3B KIAA0700 ENSG00000127511 "SIN3 transcription regulator family member B" O75182 19 16829398-16880353 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 226.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050329 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 23: Non-specific - Transcription" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 31 Nucleoplasm "Plasma membrane" "HPA050329: " "unprognostic (1.69e-1)" "unprognostic (6.13e-2)" "unprognostic (1.81e-2)" "unprognostic (4.70e-2)" "unprognostic (7.69e-3)" "unprognostic (5.77e-2)" "unprognostic (2.51e-1)" "unprognostic (2.16e-1)" "unprognostic (2.12e-2)" "unprognostic (3.52e-2)" "unprognostic (1.61e-1)" "unprognostic (1.60e-2)" "unprognostic (1.63e-1)" "unprognostic (7.18e-2)" "unprognostic (4.11e-1)" "unprognostic (2.19e-1)" "unprognostic (2.20e-1)" "unprognostic (3.87e-2)" "unprognostic (1.24e-2)" "unprognostic (6.23e-2)" "unprognostic (6.41e-2)" "unprognostic (5.17e-3)" "unprognostic (2.59e-3)" "unprognostic (5.84e-3)" "unprognostic (4.62e-2)" "potential prognostic favorable (1.41e-5)" "potential prognostic unfavorable (8.51e-4)" "unprognostic (5.84e-2)" "unprognostic (2.70e-1)" "unprognostic (6.12e-2)" "unprognostic (4.03e-2)" SINHCAF "C12orf14, FAM60A, TERA" ENSG00000139146 "SIN3-HDAC complex associated factor" Q9NP50 12 31280584-31327058 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 170.1;Early spermatids: 158.7;Epididymal basal cells: 107.5;Fallopian secretory cells: 115.3;Fallopian tube ciliated cells: 113.8;Renal collecting duct intercalated cells: 128.5" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 75.9;choroid plexus epithelial cell: 117.3;leukocyte: 53.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast myoepithelial cells, Skeletal muscle - Endothelial cells, Spleen - B-cells (Spleen), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038167, HPA057585" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 38: Non-specific - Transcription" "Cluster 102: Non-specific - Mixed function" 53 Nucleoplasm Cytosol "HPA038167: , HPA057585: " "unprognostic (1.61e-1)" "unprognostic (7.41e-2)" "unprognostic (1.52e-1)" "unprognostic (1.56e-1)" "unprognostic (1.58e-1)" "unprognostic (1.90e-3)" "unprognostic (2.14e-3)" "unprognostic (3.49e-2)" "unprognostic (9.93e-2)" "potential prognostic favorable (1.24e-4)" "unprognostic (3.66e-1)" "unprognostic (1.82e-2)" "unprognostic (1.22e-3)" "unprognostic (2.37e-1)" "unprognostic (5.33e-3)" "unprognostic (1.07e-1)" "unprognostic (5.91e-2)" "unprognostic (1.97e-2)" "unprognostic (6.14e-2)" "potential prognostic unfavorable (6.93e-4)" "unprognostic (5.95e-3)" "unprognostic (4.75e-2)" "unprognostic (2.70e-3)" "unprognostic (2.24e-2)" "unprognostic (2.64e-1)" "unprognostic (3.10e-1)" "unprognostic (1.45e-1)" "unprognostic (1.12e-1)" "unprognostic (8.73e-2)" SIPA1 SPA1 ENSG00000213445 "Signal-induced proliferation-associated 1" Q96FS4 11 65638101-65650918 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 90.4" "Cell type enhanced" "Detected in many" "Breast lactating cells: 81.0;Esophageal apical cells: 94.4;Neutrophil progenitors: 87.9;Neutrophils: 161.3;NK-cells: 84.4" "Group enriched" "Detected in many" 4 "central nervous system macrophage: 52.8;endothelial cell: 23.7;fibroblast: 13.7;leukocyte: 49.5;pericyte: 35.0;vascular associated smooth muscle cell: 14.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Liver - Vascular endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020833, HPA039867" Enhanced Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Plasma membrane" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 5 Nucleoli "Nucleoplasm, Golgi apparatus, Plasma membrane" "CAB020833: , HPA039867: " "unprognostic (4.20e-2)" "unprognostic (1.34e-1)" "unprognostic (2.50e-2)" "unprognostic (1.98e-2)" "unprognostic (3.21e-2)" "unprognostic (3.48e-1)" "unprognostic (1.13e-1)" "unprognostic (1.74e-1)" "unprognostic (3.32e-2)" "unprognostic (5.31e-2)" "unprognostic (2.47e-1)" "unprognostic (9.18e-2)" "unprognostic (3.84e-1)" "unprognostic (3.09e-2)" "unprognostic (1.32e-1)" "unprognostic (2.89e-1)" "unprognostic (6.57e-3)" "unprognostic (1.83e-3)" "unprognostic (1.84e-1)" "unprognostic (4.66e-3)" "unprognostic (2.50e-1)" "unprognostic (1.32e-1)" "unprognostic (7.22e-2)" "unprognostic (4.12e-1)" "unprognostic (8.05e-2)" "unprognostic (6.69e-2)" "unprognostic (1.05e-1)" "unprognostic (6.51e-2)" "unprognostic (3.72e-2)" "unprognostic (1.99e-1)" "unprognostic (2.25e-2)" SIPA1L1 "E6TP1, KIAA0440, SPAR1" ENSG00000197555 "Signal induced proliferation associated 1 like 1" O43166 14 71320449-71741229 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 2647.2;Neutrophils: 3404.9;Pituicytes/FSCs: 1745.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 21.6" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Smooth muscle cells, Spleen - Endothelial cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002875, HPA077689" Approved Enhanced "Plasma membrane,Actin filaments" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 23: Choroid plexus - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 26 "Plasma membrane" "Actin filaments" "HPA002875: , HPA077689: " "unprognostic (7.77e-2)" "unprognostic (1.00e-1)" "unprognostic (1.37e-1)" "unprognostic (2.85e-2)" "unprognostic (5.26e-2)" "unprognostic (4.72e-1)" "unprognostic (2.92e-1)" "unprognostic (2.12e-2)" "unprognostic (1.99e-1)" "unprognostic (3.95e-2)" "potential prognostic favorable (5.04e-8)" "unprognostic (2.22e-2)" "unprognostic (6.02e-2)" "unprognostic (2.33e-2)" "unprognostic (2.56e-1)" "unprognostic (1.13e-1)" "unprognostic (1.04e-1)" "unprognostic (3.71e-2)" "unprognostic (9.49e-2)" "unprognostic (8.39e-2)" "unprognostic (2.54e-1)" "unprognostic (6.16e-2)" "unprognostic (5.67e-2)" "unprognostic (3.29e-1)" "unprognostic (7.14e-2)" "unprognostic (6.45e-2)" "unprognostic (2.12e-1)" "unprognostic (1.03e-1)" "unprognostic (1.18e-1)" "unprognostic (5.10e-2)" "unprognostic (1.48e-1)" SIPA1L2 "KIAA1389, SPAR2" ENSG00000116991 "Signal induced proliferation associated 1 like 2" Q9P2F8 1 232397965-232630571 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglia: 522.7;Neutrophils: 1155.9;Pituicytes/FSCs: 647.2;Pituitary stem cells: 504.1;Schwann cells: 522.9" "Cell type enhanced" "Detected in all" "midbrain-derived inhibitory: 664.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Skeletal muscle - Endothelial cells, Spleen - Fibroblasts_1, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024181, HPA027224" Approved Approved "Nucleoplasm,Nuclear membrane,Nuclear bodies,Golgi apparatus" No NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 35: Non-specific - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 24: Neutrophils - Innate immunity signal integration" 35 "Nucleoplasm, Nuclear membrane, Nuclear bodies" "Golgi apparatus" "HPA024181: , HPA027224: " "unprognostic (5.34e-2)" "unprognostic (6.66e-2)" "unprognostic (2.29e-2)" "unprognostic (9.70e-2)" "unprognostic (1.52e-2)" "unprognostic (9.97e-3)" "unprognostic (2.00e-1)" "unprognostic (9.37e-2)" "unprognostic (5.66e-2)" "unprognostic (6.13e-3)" "potential prognostic favorable (4.03e-5)" "unprognostic (4.68e-3)" "unprognostic (1.90e-3)" "unprognostic (7.75e-3)" "unprognostic (1.22e-1)" "unprognostic (1.36e-1)" "unprognostic (1.24e-1)" "unprognostic (1.49e-1)" "unprognostic (6.38e-3)" "unprognostic (1.83e-2)" "unprognostic (4.97e-2)" "unprognostic (3.39e-2)" "unprognostic (9.80e-2)" "unprognostic (3.12e-1)" "unprognostic (1.26e-2)" "unprognostic (2.00e-1)" "unprognostic (1.24e-1)" "unprognostic (1.48e-1)" "unprognostic (4.22e-1)" "unprognostic (8.90e-3)" "unprognostic (8.96e-3)" SIPA1L3 "KIAA0545, SPAR3" ENSG00000105738 "Signal induced proliferation associated 1 like 3" O60292 19 37907208-38208369 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "GTPase activation" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Retinal amacrine cells: 1038.7" "Cell type enhanced" "Detected in all" "cerebellar inhibitory: 750.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Spleen - B-cells (Spleen), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042072, HPA045480, HPA074988" Uncertain Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 29: Forebrain - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 26 "Plasma membrane" "Nucleoplasm, Golgi apparatus" "HPA042072: , HPA045480: , HPA074988: " "unprognostic (1.50e-2)" "unprognostic (8.56e-2)" "unprognostic (3.13e-1)" "unprognostic (3.05e-2)" "unprognostic (1.02e-1)" "unprognostic (2.09e-2)" "unprognostic (3.85e-2)" "unprognostic (1.25e-1)" "unprognostic (1.99e-2)" "unprognostic (5.30e-2)" "unprognostic (1.25e-1)" "unprognostic (3.69e-2)" "unprognostic (2.47e-1)" "unprognostic (1.30e-2)" "unprognostic (3.41e-2)" "unprognostic (2.89e-1)" "unprognostic (6.65e-2)" "unprognostic (1.78e-1)" "unprognostic (1.15e-1)" "unprognostic (6.30e-2)" "unprognostic (1.91e-1)" "unprognostic (1.63e-1)" "unprognostic (3.36e-2)" "unprognostic (4.08e-2)" "unprognostic (6.50e-3)" "unprognostic (1.23e-1)" "unprognostic (1.46e-1)" "unprognostic (2.08e-1)" "unprognostic (3.06e-1)" "unprognostic (2.94e-2)" "unprognostic (6.14e-2)" SIRPA "BIT, CD172a, MFR, MYD-1, P84, PTPNS1, SHPS-1, SHPS1, SIRP, SIRP-ALPHA-1, SIRPalpha, SIRPalpha2" ENSG00000198053 "Signal regulatory protein alpha" P78324 20 1894167-1940592 "CD markers, Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 159.6" "Cell type enhanced" "Detected in many" "Astrocytes: 160.1;Bergmann glia: 113.4;Hofbauer cells: 143.4;Macrophages: 128.0;monocytes: 215.2;Neutrophil progenitors: 183.4;Neutrophils: 800.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 24.1;eosinophil: 48.7;myeloid DC: 13.9;neutrophil: 50.9" "Group enriched" "Detected in many" 150 "dendritic cells: 13.9;granulocytes: 50.9;monocytes: 24.1" "Cancer enhanced" "Detected in many" "Kidney cancer: 121.9" "Adipose subcutaneous - Macrophages, Spleen - Neutrophils_2, Testis - Spermatogonia" "CAB002776, CAB015122, HPA054437, HPA058511" Enhanced NA NA 14000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 27 "CAB002776: , CAB015122: , HPA054437: , HPA058511: " "unprognostic (3.03e-1)" "unprognostic (2.49e-1)" "unprognostic (5.66e-2)" "unprognostic (3.50e-2)" "unprognostic (3.74e-1)" "unprognostic (1.45e-1)" "unprognostic (4.20e-2)" "unprognostic (7.66e-2)" "unprognostic (9.21e-2)" "unprognostic (1.87e-1)" "unprognostic (3.78e-2)" "unprognostic (3.22e-1)" "unprognostic (4.90e-2)" "potential prognostic unfavorable (9.92e-5)" "unprognostic (1.51e-1)" "unprognostic (1.18e-1)" "unprognostic (2.34e-2)" "potential prognostic unfavorable (8.92e-4)" "unprognostic (6.37e-2)" "unprognostic (1.03e-2)" "unprognostic (1.55e-1)" "unprognostic (4.44e-1)" "unprognostic (1.97e-1)" "unprognostic (1.54e-1)" "unprognostic (1.89e-1)" "unprognostic (1.60e-1)" "unprognostic (4.09e-2)" "unprognostic (1.57e-1)" "unprognostic (9.68e-3)" "unprognostic (1.65e-1)" "unprognostic (8.18e-2)" SIRPB1 "CD172b, SIRP-BETA-1" ENSG00000101307 "Signal regulatory protein beta 1" "O00241, Q5TFQ8" 20 1561385-1620061 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 49.3;lung: 18.3;lymphoid tissue: 27.0" "Cell type enhanced" "Detected in some" "Kupffer cells: 1.0;monocytes: 2.3;Neutrophil progenitors: 3.9;Neutrophils: 11.2;pDCs: 1.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1606.1" "Group enriched" "Detected in all" 6 "granulocytes: 1606.1;monocytes: 503.9" "Cancer enhanced" "Detected in many" "Leukemia: 18.6;thyroid cancer: 23.3" "Adipose subcutaneous - Macrophages, Adipose visceral - Neutrophils, Liver - Neutrophils, Lung - Neutrophils_2, Spleen - Neutrophils_2, Testis - Early spermatids, Testis - Late spermatids" HPA047463 Uncertain Uncertain Vesicles,Centrosome NA NA 4700000 "Cluster 7: Non-specific - Innate immune response" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 34: Non-specific - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 4 Vesicles Centrosome "HPA047463: " "unprognostic (3.94e-1)" "unprognostic (3.17e-2)" "unprognostic (1.34e-1)" "unprognostic (6.16e-3)" "unprognostic (1.43e-1)" "unprognostic (4.91e-3)" "unprognostic (4.11e-2)" "unprognostic (2.25e-1)" "unprognostic (1.18e-1)" "unprognostic (2.69e-1)" "unprognostic (3.07e-2)" "unprognostic (4.84e-2)" "unprognostic (3.27e-1)" "unprognostic (9.23e-2)" "unprognostic (1.56e-1)" "unprognostic (4.18e-2)" "unprognostic (1.50e-1)" "unprognostic (7.83e-2)" "unprognostic (1.76e-3)" "unprognostic (1.45e-1)" "unprognostic (1.84e-1)" "unprognostic (2.30e-1)" "unprognostic (8.36e-2)" "unprognostic (1.43e-1)" "unprognostic (2.14e-2)" "unprognostic (3.26e-3)" "unprognostic (9.74e-3)" "unprognostic (8.80e-2)" SIRPB2 "dJ776F14.2, PTPN1L, PTPNS1L3" ENSG00000196209 "Signal regulatory protein beta 2" Q5JXA9 20 1470741-1491587 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 12.4" "Cell type enhanced" "Detected in some" "cDC: 31.8;Hofbauer cells: 29.5;Kupffer cells: 94.3;Macrophages: 56.5;Microglia: 47.4;Monocyte progenitors: 97.7;monocytes: 95.0;Neutrophil progenitors: 85.7;Neutrophils: 279.6" "Cell type enriched" "Detected in some" 5 "central nervous system macrophage: 62.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 12 "classical monocyte: 51.1;eosinophil: 31.7;intermediate monocyte: 30.4;myeloid DC: 21.1;neutrophil: 69.6;non-classical monocyte: 24.5" "Group enriched" "Detected in many" 331 "dendritic cells: 21.1;granulocytes: 69.6;monocytes: 51.1" "Cancer enhanced" "Detected in some" "Leukemia: 4.7" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Spleen - Neutrophils_2, Stomach - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in many" "HPA011548, HPA048032" Uncertain Approved "Nuclear bodies" NA NA 210000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" "Nuclear bodies" "HPA011548: , HPA048032: " "unprognostic (1.28e-1)" "unprognostic (5.95e-2)" "unprognostic (4.59e-2)" "unprognostic (2.72e-1)" "unprognostic (1.36e-1)" "unprognostic (4.71e-2)" "unprognostic (3.19e-2)" "unprognostic (1.47e-1)" "unprognostic (3.80e-2)" "unprognostic (7.26e-3)" "unprognostic (1.37e-1)" "unprognostic (9.09e-2)" "unprognostic (3.63e-1)" "unprognostic (2.16e-1)" "unprognostic (2.30e-2)" "unprognostic (8.25e-3)" "unprognostic (1.11e-1)" "unprognostic (4.66e-2)" "unprognostic (1.12e-1)" "unprognostic (3.10e-1)" "unprognostic (1.07e-1)" "unprognostic (9.03e-2)" "unprognostic (4.39e-2)" "unprognostic (6.83e-3)" "unprognostic (4.65e-3)" "unprognostic (1.22e-1)" SIRPD "dJ576H24.4, PTPNS1L2" ENSG00000125900 "Signal regulatory protein delta" Q9H106 20 1534251-1557705 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 24 "testis: 65.1" "Group enriched" "Detected in some" 5 "Early spermatids: 428.5;Late spermatids: 520.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "neutrophil: 37.4" "Group enriched" "Detected in many" 4 "granulocytes: 37.4;monocytes: 21.1" "Cancer enhanced" "Detected in single" "thyroid cancer: 1.2" "Testis - Late spermatids" "Not detected" "Not detected" HPA042663 Enhanced "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 47: Testis - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 51 "HPA042663: " "unprognostic (1.70e-1)" SIRPG "bA77C3.1, CD172g, SIRP-B2, SIRPB2, SIRPgamma" ENSG00000089012 "Signal regulatory protein gamma" Q9P1W8 20 1629152-1657779 "CD markers, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 36.4" "Cell type enhanced" "Detected in some" "Early spermatids: 29.9;Late primary spermatocytes: 61.3;Late spermatids: 12.7;NK-cells: 10.0;T-cells: 44.4" "Group enriched" "Detected in some" 19 "leukocyte: 24.2;pericyte: 7.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 370.4" "Lineage enriched" "Detected in many" 6 "T-cells: 370.4" "Cancer enhanced" "Detected in some" "Leukemia: 2.5;thyroid cancer: 4.2" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Minor Salivary Gland - T-cells, Pancreas - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Skin - T-cells, Spleen - T-cells, Stomach - T-cells, Testis - Early spermatids, Testis - Late spermatids" NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" 2 "unprognostic (3.44e-2)" "unprognostic (5.18e-3)" "unprognostic (8.88e-2)" "unprognostic (3.11e-2)" "unprognostic (1.14e-1)" "unprognostic (1.20e-1)" "potential prognostic favorable (2.62e-4)" "unprognostic (1.30e-1)" "unprognostic (3.56e-1)" "unprognostic (1.19e-2)" "unprognostic (6.59e-2)" "unprognostic (3.89e-3)" "unprognostic (3.71e-2)" "unprognostic (4.28e-1)" "unprognostic (3.14e-1)" "unprognostic (1.03e-1)" "unprognostic (2.95e-2)" "unprognostic (5.75e-2)" "unprognostic (1.37e-1)" "unprognostic (8.93e-2)" "unprognostic (1.55e-2)" "unprognostic (9.48e-2)" "unprognostic (2.21e-3)" "unprognostic (1.34e-1)" "unprognostic (3.50e-2)" "unprognostic (8.75e-2)" "unprognostic (2.33e-1)" SIRT1 SIR2L1 ENSG00000096717 "Sirtuin 1" Q96EB6 10 67884656-67918390 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Biological rhythms, Differentiation, Host-virus interaction, Myogenesis, Transcription, Transcription regulation" "Developmental protein, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 379.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003855, HPA006295, HPA052351" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Mitochondria,Cytosol" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 225 Nucleoplasm "Nucleoli fibrillar center, Mitochondria, Cytosol" "CAB003855: , HPA006295: , HPA052351: " "unprognostic (2.69e-3)" "unprognostic (6.66e-2)" "unprognostic (1.67e-1)" "unprognostic (1.44e-2)" "unprognostic (2.25e-1)" "unprognostic (7.94e-2)" "unprognostic (1.42e-1)" "potential prognostic favorable (2.17e-5)" "unprognostic (1.12e-1)" "unprognostic (1.59e-1)" "potential prognostic favorable (2.32e-6)" "unprognostic (2.40e-3)" "unprognostic (1.14e-1)" "unprognostic (2.25e-1)" "unprognostic (3.58e-1)" "unprognostic (2.26e-1)" "unprognostic (2.11e-1)" "unprognostic (1.55e-1)" "unprognostic (3.02e-1)" "unprognostic (1.80e-1)" "unprognostic (5.89e-3)" "unprognostic (1.04e-1)" "unprognostic (6.90e-2)" "unprognostic (4.82e-2)" "unprognostic (2.06e-1)" "unprognostic (1.35e-1)" "unprognostic (1.11e-1)" "unprognostic (1.12e-2)" "unprognostic (1.82e-1)" "unprognostic (5.40e-2)" "unprognostic (1.67e-1)" SIRT2 SIR2L ENSG00000068903 "Sirtuin 2" Q8IXJ6 19 38878555-38899862 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Autophagy, Cell cycle, Cell division, Differentiation, Immunity, Innate immunity, Meiosis, Mitosis, Neurogenesis, Transcription, Transcription regulation" Transferase "Cancer-related genes, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "brain: 492.9;skeletal muscle: 306.9;tongue: 203.7" "Group enriched" "Detected in many" 4 "Oligodendrocyte progenitor cells: 132.5;Oligodendrocytes: 303.3" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 721.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Skeletal myocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004573, HPA011165" Approved Supported "Nucleoplasm,Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 4: Non-specific - Transcription" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 22 "Nucleoli, Cytosol" "Nucleoplasm, Plasma membrane" "CAB004573: , HPA011165: " "unprognostic (7.74e-2)" "unprognostic (4.23e-1)" "unprognostic (3.12e-2)" "unprognostic (6.02e-2)" "unprognostic (2.22e-1)" "unprognostic (4.83e-3)" "unprognostic (2.29e-3)" "unprognostic (7.65e-2)" "unprognostic (2.47e-2)" "unprognostic (1.84e-1)" "potential prognostic favorable (5.94e-6)" "unprognostic (1.62e-1)" "unprognostic (1.27e-1)" "unprognostic (1.80e-1)" "unprognostic (3.02e-2)" "unprognostic (2.82e-3)" "unprognostic (3.10e-1)" "unprognostic (7.14e-2)" "unprognostic (1.70e-1)" "unprognostic (8.56e-2)" "unprognostic (6.28e-2)" "unprognostic (3.32e-2)" "unprognostic (1.24e-1)" "unprognostic (3.98e-1)" "unprognostic (7.98e-2)" "unprognostic (3.57e-2)" "unprognostic (8.27e-2)" "unprognostic (9.71e-2)" "unprognostic (1.11e-1)" "unprognostic (2.50e-1)" "unprognostic (1.05e-2)" SIRT3 SIR2L3 ENSG00000142082 "Sirtuin 3" Q9NTG7 11 215030-236931 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB037142 Supported NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 22: Epididymis - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 7: Non-specific - Transcription" 32 "CAB037142: " "unprognostic (4.19e-2)" "unprognostic (1.86e-1)" "unprognostic (1.12e-1)" "unprognostic (6.48e-2)" "potential prognostic unfavorable (9.26e-4)" "unprognostic (1.54e-1)" "unprognostic (1.12e-2)" "unprognostic (5.20e-3)" "unprognostic (2.68e-1)" "unprognostic (1.99e-1)" "unprognostic (5.94e-2)" "unprognostic (1.79e-3)" "potential prognostic favorable (6.88e-5)" "unprognostic (2.85e-1)" "unprognostic (6.66e-2)" "unprognostic (8.24e-2)" "unprognostic (5.29e-2)" "unprognostic (3.26e-2)" "unprognostic (1.53e-1)" "unprognostic (3.20e-1)" "unprognostic (2.23e-1)" "unprognostic (4.73e-3)" "unprognostic (4.57e-3)" "unprognostic (2.51e-1)" "unprognostic (1.25e-2)" "unprognostic (2.51e-1)" "unprognostic (7.72e-2)" "unprognostic (1.13e-1)" "unprognostic (1.49e-1)" "unprognostic (1.31e-1)" "unprognostic (1.37e-1)" SIRT4 SIR2L4 ENSG00000089163 "Sirtuin 4" Q9Y6E7 12 120302316-120313249 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "DNA damage" "Glycosyltransferase, Nucleotidyltransferase, Transferase" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 39.0;Late primary spermatocytes: 42.1;Myonuclei: 28.0;Rod photoreceptor cells: 17.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029691, HPA029692" Enhanced NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 37: Neurons - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" 9 "HPA029691: , HPA029692: " "unprognostic (2.21e-3)" "unprognostic (2.98e-3)" "unprognostic (2.79e-2)" "unprognostic (4.53e-2)" "unprognostic (8.72e-2)" "potential prognostic favorable (4.93e-4)" "unprognostic (2.40e-2)" "unprognostic (7.55e-2)" "potential prognostic favorable (1.67e-5)" "unprognostic (1.55e-2)" "unprognostic (3.31e-1)" "unprognostic (1.15e-2)" "unprognostic (1.18e-1)" "unprognostic (1.77e-2)" "unprognostic (1.34e-2)" "unprognostic (3.01e-1)" "unprognostic (1.55e-1)" "unprognostic (2.63e-2)" "potential prognostic unfavorable (3.39e-4)" "unprognostic (4.01e-3)" "unprognostic (1.71e-1)" "unprognostic (3.15e-1)" "unprognostic (1.87e-1)" "unprognostic (3.28e-2)" "unprognostic (1.99e-1)" "unprognostic (1.15e-2)" "unprognostic (2.81e-2)" SIRT5 ENSG00000124523 "Sirtuin 5" Q9NXA8 6 13574227-13615158 "Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 118.4;Neutrophil progenitors: 125.8;Neutrophils: 138.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021798, HPA022002, HPA022992" Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 76: Non-specific - Metabolism" "Cluster 53: Neurons - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 8 Mitochondria "HPA021798: , HPA022002: , HPA022992: " "unprognostic (4.94e-2)" "unprognostic (4.77e-3)" "unprognostic (1.70e-1)" "unprognostic (7.94e-2)" "unprognostic (3.39e-2)" "unprognostic (3.47e-1)" "unprognostic (1.75e-2)" "unprognostic (2.06e-1)" "unprognostic (1.20e-1)" "unprognostic (9.07e-2)" "validated prognostic favorable (1.83e-6)" "validated prognostic favorable (2.84e-5)" "unprognostic (2.13e-3)" "unprognostic (2.75e-1)" "unprognostic (1.60e-2)" "unprognostic (1.20e-1)" "unprognostic (3.07e-1)" "unprognostic (1.42e-1)" "potential prognostic favorable (5.81e-4)" "potential prognostic favorable (4.81e-4)" "unprognostic (1.57e-1)" "unprognostic (5.00e-2)" "unprognostic (2.87e-1)" "unprognostic (8.89e-3)" "potential prognostic favorable (6.21e-7)" "unprognostic (8.51e-2)" "unprognostic (1.81e-2)" "unprognostic (2.30e-1)" "unprognostic (1.29e-1)" "unprognostic (4.59e-2)" "unprognostic (2.14e-1)" SIRT6 ENSG00000077463 "Sirtuin 6" Q8N6T7 19 4174109-4182566 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Acyltransferase, Chromatin regulator, Developmental protein, DNA-binding, Glycosyltransferase, Nucleotidyltransferase, RNA-binding, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Colonocytes: 261.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049729, HPA071776" Supported Supported Nucleoplasm,Vesicles No No "Cluster 29: Non-specific - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 18: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 98 Nucleoplasm Vesicles "HPA049729: , HPA071776: " "unprognostic (1.33e-1)" "unprognostic (1.19e-1)" "unprognostic (2.38e-1)" "unprognostic (7.01e-3)" "unprognostic (2.53e-1)" "unprognostic (1.44e-1)" "unprognostic (2.41e-1)" "unprognostic (1.58e-1)" "unprognostic (4.38e-2)" "unprognostic (1.19e-1)" "unprognostic (1.90e-1)" "unprognostic (9.64e-2)" "unprognostic (1.24e-1)" "potential prognostic unfavorable (1.22e-4)" "unprognostic (2.01e-2)" "unprognostic (1.14e-1)" "unprognostic (1.53e-1)" "unprognostic (8.53e-2)" "unprognostic (1.78e-1)" "unprognostic (3.84e-2)" "unprognostic (7.85e-2)" "unprognostic (1.95e-2)" "unprognostic (7.59e-2)" "unprognostic (6.28e-2)" "unprognostic (2.17e-1)" "unprognostic (1.07e-1)" "unprognostic (1.58e-2)" "unprognostic (2.01e-3)" "unprognostic (1.25e-1)" "unprognostic (1.27e-1)" "unprognostic (5.90e-2)" SIRT7 ENSG00000187531 "Sirtuin 7" Q9NRC8 17 81911939-81921323 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 497.3;Esophageal suprabasal cells: 177.4;Foveolar cells: 121.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 22.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027284, HPA028246, CAB037261, HPA053669" Approved Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 27: Breast cancer - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 30 Nucleoplasm "Nuclear speckles" "CAB037261: , HPA027284: , HPA028246: , HPA053669: " "unprognostic (1.74e-2)" "unprognostic (9.58e-2)" "unprognostic (7.14e-2)" "unprognostic (2.57e-1)" "unprognostic (9.70e-2)" "unprognostic (8.07e-2)" "unprognostic (3.13e-1)" "potential prognostic favorable (7.12e-4)" "unprognostic (1.02e-1)" "unprognostic (8.89e-3)" "unprognostic (1.97e-1)" "unprognostic (1.31e-1)" "unprognostic (6.18e-2)" "potential prognostic unfavorable (1.81e-6)" "unprognostic (3.55e-2)" "unprognostic (8.19e-2)" "unprognostic (3.92e-2)" "unprognostic (9.36e-3)" "unprognostic (2.71e-1)" "unprognostic (1.38e-1)" "potential prognostic favorable (3.27e-4)" "unprognostic (4.20e-2)" "unprognostic (1.12e-1)" "unprognostic (6.90e-2)" "unprognostic (5.74e-2)" "unprognostic (1.19e-1)" "unprognostic (2.38e-1)" "unprognostic (1.81e-2)" "unprognostic (2.80e-1)" "unprognostic (6.68e-2)" "unprognostic (3.90e-3)" SIT1 SIT ENSG00000137078 "Signaling threshold regulating transmembrane adaptor 1" Q9Y3P8 9 35649295-35650931 "Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 87.5" "Cell type enhanced" "Detected in some" "B-cells: 42.8;pDCs: 77.8;Plasma cells: 17.8;T-cells: 66.8" "Cell type enriched" "Detected in single" 197 "leukocyte: 30.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 46 "gdT-cell: 119.1;MAIT T-cell: 203.6;memory B-cell: 215.4;memory CD4 T-cell: 250.7;memory CD8 T-cell: 223.7;naive B-cell: 193.3;naive CD4 T-cell: 171.4;naive CD8 T-cell: 170.2;plasmacytoid DC: 202.0;T-reg: 354.3" "Group enriched" "Detected in many" 56 "B-cells: 215.4;dendritic cells: 202.0;T-cells: 354.3" "Group enriched" "Detected in some" 9 "Leukemia: 23.7;lymphoma: 82.2" "Colon - T-cells, Lung - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Skin - T-cells, Spleen - B-cells (Spleen), Stomach - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA018506 Enhanced NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 9: T-cells - Adaptive immunity: Regulation" 10 "HPA018506: " "unprognostic (1.29e-1)" "unprognostic (1.40e-3)" "unprognostic (1.10e-1)" "unprognostic (3.35e-3)" "unprognostic (2.59e-2)" "unprognostic (9.45e-2)" "unprognostic (1.13e-2)" "potential prognostic favorable (3.96e-5)" "unprognostic (1.71e-1)" "unprognostic (1.43e-1)" "potential prognostic unfavorable (8.51e-4)" "unprognostic (6.95e-2)" "unprognostic (1.25e-2)" "unprognostic (8.04e-3)" "unprognostic (3.23e-2)" "unprognostic (6.67e-2)" "unprognostic (2.22e-1)" "unprognostic (5.12e-2)" "unprognostic (6.96e-2)" "unprognostic (2.66e-1)" "unprognostic (2.76e-1)" "unprognostic (1.22e-1)" "unprognostic (1.20e-1)" "unprognostic (1.48e-1)" "unprognostic (1.18e-3)" "unprognostic (2.29e-1)" "unprognostic (1.41e-2)" "unprognostic (9.99e-2)" "unprognostic (2.38e-1)" SIVA1 "CD27BP, SIVA, Siva-1, Siva-2" ENSG00000184990 "SIVA1 apoptosis inducing factor" O15304 14 104753147-104768494 "Predicted intracellular proteins" "Apoptosis, Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early primary spermatocytes: 419.9;Late primary spermatocytes: 451.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065398, HPA066693" Enhanced Nucleoplasm NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 24: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 97: Non-specific - Cellular respiration" 23 Nucleoplasm "HPA065398: , HPA066693: " "unprognostic (1.17e-1)" "unprognostic (1.19e-1)" "unprognostic (1.04e-2)" "potential prognostic favorable (3.34e-4)" "unprognostic (2.81e-1)" "unprognostic (1.23e-1)" "unprognostic (1.22e-1)" "unprognostic (7.73e-3)" "unprognostic (8.77e-2)" "unprognostic (2.93e-1)" "unprognostic (3.93e-1)" "unprognostic (9.84e-2)" "unprognostic (5.39e-2)" "unprognostic (2.11e-3)" "potential prognostic unfavorable (2.25e-4)" "unprognostic (3.25e-2)" "unprognostic (1.13e-1)" "unprognostic (9.08e-2)" "unprognostic (1.34e-1)" "unprognostic (6.62e-2)" "unprognostic (1.70e-1)" "unprognostic (1.36e-2)" "unprognostic (2.69e-1)" "unprognostic (1.25e-1)" "unprognostic (2.69e-1)" "unprognostic (1.82e-1)" "unprognostic (1.46e-1)" "unprognostic (1.10e-3)" "unprognostic (3.82e-1)" "unprognostic (2.49e-1)" "unprognostic (3.27e-1)" SIX1 DFNA23 ENSG00000126778 "SIX homeobox 1" Q15475 14 60643421-60658259 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 45.0;salivary gland: 48.1;skeletal muscle: 111.8;tongue: 43.2" "Cell type enhanced" "Detected in some" "Adipocytes: 75.2;Conjunctival goblet cells: 92.2;Endometrial secretory cells: 81.7;Gonadotrophs: 125.1;Lacrimal acinar cells: 136.8;Medullary thymic epithelial cells: 134.4;Myonuclei: 149.2;Myosatellite cells: 104.2;Pituitary stem cells: 110.1;Respiratory basal cells: 64.5;Respiratory ciliated cells: 88.5;Respiratory deuterosomal cells: 60.1;Respiratory secretory cells: 69.5;Salivary acinar cells: 89.1;Salivary duct cells: 68.1;Thymic myoid cells: 84.3" "Group enriched" "Detected in some" 35 "fibroblast: 17.3;pericyte: 28.3;vascular associated smooth muscle cell: 9.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Adipocytes (Breast), Lung - Respiratory ciliated cells, Testis - Spermatogonia" "Not detected" "Not detected" "Region enhanced" "Detected in some" "spinal cord: 5.5" "HPA001893, CAB058690" Enhanced Supported Nucleoplasm,Nucleoli No No "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 22 Nucleoplasm Nucleoli "CAB058690: , HPA001893: " "unprognostic (7.73e-2)" "unprognostic (6.35e-2)" "unprognostic (2.81e-1)" "potential prognostic favorable (4.67e-4)" "unprognostic (5.46e-2)" "unprognostic (7.24e-2)" "unprognostic (1.16e-2)" "unprognostic (4.18e-2)" "unprognostic (7.55e-3)" "unprognostic (1.11e-3)" "potential prognostic unfavorable (3.04e-4)" "unprognostic (3.28e-3)" "unprognostic (7.30e-2)" "unprognostic (1.15e-1)" "unprognostic (1.65e-1)" "unprognostic (4.14e-2)" "unprognostic (5.56e-3)" "unprognostic (5.67e-1)" "unprognostic (7.36e-3)" "unprognostic (7.21e-2)" "unprognostic (9.34e-2)" "unprognostic (3.82e-1)" "unprognostic (3.35e-3)" SIX2 ENSG00000170577 "SIX homeobox 2" Q9NPC8 2 45005182-45009452 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 19.9;skeletal muscle: 32.0" "Cell type enhanced" "Detected in some" "Conjunctival goblet cells: 9.7;Gonadotrophs: 9.0;Lacrimal acinar cells: 12.7;Medullary thymic epithelial cells: 19.2;Respiratory basal cells: 19.7;Respiratory deuterosomal cells: 14.5;Respiratory ionocytes: 17.8;Respiratory secretory cells: 11.8;Salivary basal cells: 20.1;Salivary duct cells: 30.2;Salivary ionocytes: 13.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 27.2" "Region enhanced" "Detected in some" "pons: 3.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 19.2" "Adipose visceral - Mesothelial cells, Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" HPA056958 Supported "Nucleoplasm,Nuclear membrane" NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 44: Non-specific - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 8 Nucleoplasm "Nuclear membrane" "HPA056958: " "unprognostic (2.21e-2)" "unprognostic (3.22e-3)" "unprognostic (1.86e-2)" "unprognostic (8.96e-2)" "unprognostic (8.57e-3)" "unprognostic (1.34e-1)" "unprognostic (9.45e-2)" "unprognostic (1.19e-2)" "unprognostic (6.38e-2)" "unprognostic (6.01e-2)" "unprognostic (8.88e-2)" "unprognostic (6.05e-3)" "unprognostic (1.26e-1)" "unprognostic (1.95e-1)" "unprognostic (1.71e-2)" "potential prognostic unfavorable (9.18e-4)" "unprognostic (1.56e-2)" "unprognostic (4.91e-2)" "unprognostic (1.57e-1)" "unprognostic (1.10e-1)" "unprognostic (9.22e-2)" SIX3 HPE2 ENSG00000138083 "SIX homeobox 3" O95343 2 44941702-44946071 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Disease variant, Holoprosencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 36.9;pituitary gland: 25.1;retina: 23.5" "Group enriched" "Detected in some" 4 "Müller glia: 329.4;Pituicytes/FSCs: 183.7;Retinal amacrine cells: 115.1;Retinal bipolar cells: 115.8;Retinal horizontal cells: 106.2;Retinal pigment epithelial cells: 221.7" "Group enriched" "Detected in some" 4 "choroid plexus epithelial cell: 15.2;eccentric medium spiny neuron: 48.3;ependymal cell: 20.4;medium spiny neuron: 50.2" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 4.5" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 1.4" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Neuroblastoma: 13.6" "Lung - Respiratory ciliated cells, Pancreas - Beta cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "basal ganglia: 50.9;hypothalamus: 25.7" HPA067988 Approved Nucleoplasm NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 1: Neuronal - Visual perception" "Cluster 11: Muller glia cells - Retinal homeostasis" 5 Nucleoplasm "HPA067988: " "unprognostic (2.42e-2)" "unprognostic (2.63e-3)" "unprognostic (7.07e-2)" "unprognostic (4.50e-3)" "unprognostic (1.91e-1)" "unprognostic (2.71e-3)" "unprognostic (8.64e-2)" "unprognostic (9.03e-2)" "potential prognostic unfavorable (4.61e-5)" SIX4 AREC3 ENSG00000100625 "SIX homeobox 4" Q9UIU6 14 60709539-60724351 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "parathyroid gland: 14.2;salivary gland: 6.5;skeletal muscle: 13.1;tongue: 14.6" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 65.0;Endometrial ciliated cells: 49.3;Endometrial glandular cells: 39.2;Endometrial luminal cells: 61.6;Endometrial secretory cells: 58.7;Epididymal basal cells: 47.8;Epididymal efferent duct ciliated cells: 34.4;Medullary thymic epithelial cells: 43.2;Myonuclei: 49.5;Respiratory ciliated cells: 42.0;Thymic myoid cells: 36.7" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 13.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Lung - Respiratory ciliated cells, Stomach - Chief cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA031793, HPA031794" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 23: Choroid plexus - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 7 Nucleoplasm Cytosol "HPA031793: , HPA031794: " "unprognostic (5.82e-2)" "unprognostic (3.75e-1)" "unprognostic (1.20e-1)" "unprognostic (1.46e-1)" "unprognostic (1.11e-2)" "unprognostic (1.80e-3)" "unprognostic (1.26e-1)" "unprognostic (9.05e-2)" "unprognostic (2.50e-1)" "potential prognostic unfavorable (4.33e-4)" "unprognostic (5.04e-2)" "unprognostic (1.48e-2)" "unprognostic (6.99e-3)" "unprognostic (1.61e-2)" "unprognostic (3.40e-2)" "potential prognostic unfavorable (7.19e-5)" "unprognostic (4.91e-2)" "unprognostic (3.24e-2)" "unprognostic (3.97e-2)" "unprognostic (3.24e-1)" "potential prognostic unfavorable (3.08e-4)" "unprognostic (2.36e-1)" SIX5 DMAHP ENSG00000177045 "SIX homeobox 5" Q8N196 19 45764785-45769252 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in some" 16 "astrocyte: 12.8;Bergmann glia: 5.9;choroid plexus epithelial cell: 9.0;endothelial cell: 5.2;ependymal cell: 15.1;fibroblast: 15.6;pericyte: 14.6;vascular associated smooth muscle cell: 12.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA042068 Approved Supported "Nucleoplasm,Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 44: Non-specific - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 94: Gonadal somatic cells - Mixed function" 4 "Nucleoplasm, Golgi apparatus, Vesicles, Cytosol" "HPA042068: " "unprognostic (3.08e-2)" "unprognostic (4.66e-3)" "unprognostic (8.46e-2)" "unprognostic (2.29e-2)" "unprognostic (2.00e-2)" "unprognostic (1.48e-3)" "unprognostic (1.38e-1)" "unprognostic (2.48e-2)" "unprognostic (1.78e-1)" "unprognostic (9.33e-2)" "potential prognostic unfavorable (2.23e-7)" "unprognostic (5.64e-3)" "unprognostic (2.55e-1)" "potential prognostic unfavorable (7.22e-4)" "unprognostic (5.88e-2)" "potential prognostic unfavorable (7.22e-4)" "unprognostic (8.61e-2)" "unprognostic (2.54e-1)" "unprognostic (7.86e-2)" "unprognostic (1.82e-1)" "unprognostic (1.90e-1)" "unprognostic (1.12e-1)" "unprognostic (1.62e-1)" "unprognostic (7.83e-2)" "unprognostic (3.26e-2)" "unprognostic (2.21e-2)" "unprognostic (3.60e-2)" "unprognostic (1.26e-1)" "unprognostic (1.26e-1)" "unprognostic (4.91e-2)" "unprognostic (1.67e-1)" SIX6 "OPTX2, Six9" ENSG00000184302 "SIX homeobox 6" O95475 14 60509146-60512850 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Cataract, Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "pituitary gland: 29.0" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 47.6;Lactotrophs: 46.1;Müller glia: 152.6;Pituicytes/FSCs: 10.8;Pituitary stem cells: 18.9;Retinal horizontal cells: 24.0;Thyrotrophs: 28.5" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "Glioblastoma Multiforme (TCGA): 1.5;Kidney Chromophobe (TCGA): 2.1" "Region enriched" "Detected in single" 22 "hypothalamus: 8.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 2.0;Uterine cancer: 1.2" "Pituitary gland - Lactotropes" "Region enriched" "Detected in single" 14 "hypothalamus: 3.6" "Region enriched" "Detected in single" 12 "hypothalamus: 2.2" HPA001403 Approved Approved Nucleoplasm NA NA "Cluster 20: Pituitary gland - Hormone signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 59: Leukemia - T-cell receptor" "Cluster 11: Muller glia cells - Retinal homeostasis" 2 Nucleoplasm "HPA001403: " "unprognostic (3.50e-1)" "unprognostic (4.06e-3)" "unprognostic (1.15e-1)" SKA1 "C18orf24, MGC10200" ENSG00000154839 "Spindle and kinetochore associated complex subunit 1" Q96BD8 18 50375040-50394168 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 11.2;lymphoid tissue: 4.5" "Cell type enhanced" "Detected in some" "Early primary spermatocytes: 1.6;Early spermatids: 1.9;Erythrocyte progenitors: 7.0;Late primary spermatocytes: 1.2;Megakaryocyte progenitors: 3.4;Monocyte progenitors: 4.4;Plasma cells: 1.4" "Cell type enhanced" "Detected in some" "medium spiny neuron: 1.6;upper rhombic lip: 1.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Not detected" "Not detected" "Not detected" "Not detected" HPA045495 Approved Supported "Microtubules,Cytokinetic bridge,Primary cilium,Centriolar satellite,Basal body" Yes Yes "Cluster 21: Neutrophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 6: Non-specific - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 27 "Microtubules, Primary cilium" "Cytokinetic bridge, Centriolar satellite, Basal body" "HPA045495: " "unprognostic (1.98e-1)" "unprognostic (2.40e-2)" "unprognostic (1.17e-1)" "unprognostic (2.84e-1)" "unprognostic (3.30e-2)" "unprognostic (3.97e-1)" "unprognostic (4.56e-2)" "unprognostic (3.96e-2)" "unprognostic (1.15e-1)" "unprognostic (3.09e-3)" "potential prognostic unfavorable (1.28e-9)" "validated prognostic unfavorable (1.68e-6)" "validated prognostic unfavorable (1.20e-8)" "potential prognostic unfavorable (7.59e-5)" "unprognostic (1.29e-3)" "unprognostic (5.97e-3)" "unprognostic (2.47e-3)" "unprognostic (2.37e-2)" "unprognostic (1.63e-1)" "potential prognostic unfavorable (8.72e-4)" "unprognostic (5.90e-3)" "unprognostic (1.79e-1)" "unprognostic (1.02e-2)" "unprognostic (6.30e-2)" "unprognostic (2.57e-3)" "unprognostic (4.34e-2)" "unprognostic (3.45e-1)" SKA2 "FAM33A, FLJ12758" ENSG00000182628 "Spindle and kinetochore associated complex subunit 2" Q8WVK7 17 59109857-59155260 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 163.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059235 Uncertain NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 25: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 14 "HPA059235: " "unprognostic (2.45e-1)" "unprognostic (8.05e-2)" "unprognostic (1.56e-2)" "unprognostic (2.32e-1)" "unprognostic (1.17e-2)" "unprognostic (1.52e-1)" "unprognostic (6.48e-2)" "unprognostic (3.97e-2)" "unprognostic (1.96e-3)" "potential prognostic unfavorable (4.65e-4)" "unprognostic (5.36e-2)" "unprognostic (2.38e-1)" "potential prognostic unfavorable (3.36e-6)" "potential prognostic unfavorable (5.15e-5)" "unprognostic (3.64e-3)" "unprognostic (2.39e-3)" "unprognostic (5.27e-3)" "unprognostic (2.08e-1)" "unprognostic (7.47e-2)" "unprognostic (6.58e-3)" "unprognostic (4.94e-2)" "unprognostic (6.01e-2)" "unprognostic (3.23e-2)" "unprognostic (3.46e-2)" "unprognostic (2.67e-1)" "unprognostic (1.07e-1)" "unprognostic (8.66e-3)" "unprognostic (9.96e-2)" "unprognostic (2.50e-1)" "unprognostic (6.37e-2)" "unprognostic (2.85e-1)" SKA3 "C13orf3, MGC4832, RAMA1" ENSG00000165480 "Spindle and kinetochore associated complex subunit 3" Q8IX90 13 21153595-21176552 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.5;lymphoid tissue: 11.3;testis: 5.9" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 29.5;Early primary spermatocytes: 29.7;Enteric transient amplifying cells: 16.6;Erythrocyte progenitors: 47.8;Esophageal basal cells: 22.1;Extravillous trophoblasts: 25.1;Gastric progenitor cells: 20.5;Megakaryocyte progenitors: 36.1;Migrating cytotrophoblasts: 20.6;Monocyte progenitors: 37.8;Oocytes: 27.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA039272, HPA039356, HPA061534" Approved Uncertain "Mitotic spindle,Centrosome,Cytosol" Yes Yes "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 29: Forebrain - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 21 "Mitotic spindle, Centrosome" Cytosol "HPA039272: , HPA039356: , HPA061534: " "unprognostic (1.10e-2)" "unprognostic (6.00e-2)" "unprognostic (1.25e-1)" "unprognostic (1.28e-1)" "unprognostic (9.95e-2)" "unprognostic (1.03e-1)" "unprognostic (2.88e-1)" "unprognostic (6.89e-3)" "unprognostic (1.44e-1)" "validated prognostic unfavorable (2.72e-6)" "validated prognostic unfavorable (9.75e-9)" "validated prognostic unfavorable (1.12e-4)" "validated prognostic unfavorable (2.54e-4)" "unprognostic (3.15e-2)" "unprognostic (5.96e-2)" "unprognostic (1.31e-1)" "unprognostic (1.19e-1)" "validated prognostic unfavorable (2.78e-4)" "validated prognostic unfavorable (2.22e-4)" "unprognostic (3.76e-2)" "unprognostic (7.48e-2)" "unprognostic (3.11e-2)" "unprognostic (7.15e-3)" "unprognostic (7.28e-2)" "unprognostic (8.01e-2)" SKAP1 "SCAP1, SKAP55" ENSG00000141293 "Src kinase associated phosphoprotein 1" Q86WV1 17 48133442-48430275 "Predicted intracellular proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 33.3" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 409.3;Gonadotrophs: 303.8;Hematopoietic stem cells: 306.7;Innate lymphoid cells: 386.0;Loop of henle epithelial cells: 348.0;Mast cells: 495.8;NK-cells: 1237.0;Renal collecting duct intercalated cells: 494.0;Renal collecting duct principal cells: 365.8;Renal connecting tubule cells: 360.2;T-cells: 1058.7" "Cell type enriched" "Detected in all" 29 "leukocyte: 1622.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Myeloma: 20.8;Rhabdoid: 28.6" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Heart muscle - T-cells, Liver - Hepatocytes, Lung - T-cells, Prostate - T-cells, Spleen - T-cells, Stomach - T-cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA002969, CAB025882, CAB055513" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 9: T-cells - Adaptive immunity: Regulation" 10 "Nucleoplasm, Plasma membrane" Cytosol "CAB025882: , CAB055513: , HPA002969: " "unprognostic (1.32e-2)" "unprognostic (3.24e-2)" "unprognostic (6.75e-2)" "unprognostic (4.70e-3)" "unprognostic (2.87e-3)" "unprognostic (1.79e-2)" "unprognostic (5.36e-2)" "unprognostic (3.74e-2)" "unprognostic (1.12e-2)" "unprognostic (2.76e-1)" "unprognostic (2.29e-2)" "unprognostic (2.12e-1)" "unprognostic (1.19e-2)" "unprognostic (1.34e-1)" "unprognostic (1.74e-1)" "unprognostic (2.80e-1)" "unprognostic (1.15e-1)" "unprognostic (2.69e-1)" "unprognostic (2.70e-1)" "unprognostic (1.26e-1)" "unprognostic (5.56e-2)" "unprognostic (1.40e-2)" "unprognostic (5.14e-2)" "unprognostic (3.41e-1)" "unprognostic (2.01e-2)" "unprognostic (1.44e-1)" "unprognostic (8.71e-2)" "unprognostic (4.79e-2)" "unprognostic (2.48e-1)" "unprognostic (2.64e-2)" SKAP2 "RA70, SAPS, SCAP2, SKAP-HOM, SKAP55R" ENSG00000005020 "Src kinase associated phosphoprotein 2" O75563 7 26667068-26995239 "Predicted intracellular proteins" "B-cell activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 601.1;Microglia: 524.9;Neutrophil progenitors: 903.7;Neutrophils: 2041.6;Tuft cells: 541.8" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 705.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005560, HPA024045" Enhanced Supported Nucleoplasm,Cytosol NA NA 980000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 22: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 12 Nucleoplasm Cytosol "HPA005560: , HPA024045: " "unprognostic (6.16e-3)" "unprognostic (1.95e-1)" "unprognostic (1.54e-1)" "unprognostic (6.49e-3)" "unprognostic (3.20e-1)" "unprognostic (5.64e-2)" "unprognostic (2.41e-2)" "unprognostic (1.65e-2)" "unprognostic (2.37e-2)" "potential prognostic unfavorable (3.20e-4)" "potential prognostic favorable (6.32e-4)" "unprognostic (8.37e-2)" "unprognostic (2.72e-1)" "potential prognostic unfavorable (7.01e-4)" "unprognostic (1.01e-2)" "unprognostic (3.01e-3)" "unprognostic (1.91e-3)" "unprognostic (7.98e-2)" "potential prognostic unfavorable (4.22e-4)" "unprognostic (4.73e-3)" "unprognostic (6.92e-2)" "unprognostic (5.61e-2)" "unprognostic (1.76e-1)" "unprognostic (7.75e-2)" "unprognostic (1.37e-1)" "unprognostic (6.28e-3)" "unprognostic (1.15e-1)" "unprognostic (1.73e-1)" "unprognostic (4.81e-1)" "unprognostic (2.77e-1)" "unprognostic (1.27e-1)" SKI ENSG00000157933 "SKI proto-oncogene" P12755 1 2227388-2310213 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Craniosynostosis, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 103.1" "Cell type enhanced" "Detected in many" "Neutrophils: 378.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010449, HPA066567" Approved Supported "Nucleoplasm,Nuclear bodies,Golgi apparatus" NA NA "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 49 Nucleoplasm "Nuclear bodies, Golgi apparatus" "CAB010449: , HPA066567: " "unprognostic (1.63e-3)" "unprognostic (3.97e-1)" "unprognostic (2.45e-3)" "unprognostic (2.98e-3)" "unprognostic (4.54e-1)" "unprognostic (5.09e-2)" "unprognostic (8.96e-2)" "unprognostic (5.71e-3)" "unprognostic (9.63e-2)" "unprognostic (2.82e-2)" "validated prognostic favorable (1.54e-5)" "validated prognostic favorable (6.90e-4)" "unprognostic (1.78e-1)" "unprognostic (9.12e-2)" "unprognostic (3.18e-1)" "unprognostic (2.02e-1)" "unprognostic (2.94e-2)" "unprognostic (6.73e-3)" "unprognostic (6.36e-2)" "unprognostic (4.67e-2)" "unprognostic (1.09e-1)" "unprognostic (2.83e-1)" "unprognostic (2.98e-1)" "unprognostic (1.25e-1)" "unprognostic (2.00e-1)" "potential prognostic favorable (3.76e-4)" "unprognostic (2.26e-1)" "unprognostic (1.59e-1)" "unprognostic (1.53e-1)" "unprognostic (2.33e-2)" "unprognostic (2.03e-1)" SKIC2 "170A, DDX13, HLP, SKI2, SKI2W, SKIV2, SKIV2L, SKIV2L1" ENSG00000204351 "SKI2 subunit of superkiller complex" Q15477 6 31959116-31969818 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 16.0;Epicardial cells: 47.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 30.0" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047122, HPA051959, HPA054419" Uncertain Approved "Nucleoplasm,Nuclear bodies,Mitotic spindle,Cytosol" Yes NA "Cluster 70: Non-specific - Protein processing" "Cluster 19: Astrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 17 "Nucleoplasm, Nuclear bodies" "Mitotic spindle, Cytosol" "HPA047122: , HPA051959: , HPA054419: " "unprognostic (4.96e-1)" "unprognostic (1.11e-1)" "unprognostic (2.10e-1)" "unprognostic (2.19e-2)" "unprognostic (3.76e-1)" "unprognostic (5.10e-2)" "unprognostic (2.11e-2)" "unprognostic (1.42e-1)" "unprognostic (3.96e-2)" "unprognostic (1.68e-3)" "unprognostic (3.01e-2)" "unprognostic (1.84e-1)" "unprognostic (1.90e-1)" "unprognostic (1.61e-1)" "unprognostic (1.10e-1)" "unprognostic (4.25e-2)" "unprognostic (1.94e-1)" "unprognostic (4.59e-1)" "unprognostic (7.12e-2)" "unprognostic (1.35e-1)" "unprognostic (3.07e-2)" "unprognostic (1.82e-1)" "unprognostic (1.10e-2)" "unprognostic (1.16e-2)" "unprognostic (9.55e-2)" "unprognostic (2.39e-1)" "unprognostic (1.83e-1)" "unprognostic (5.67e-2)" "unprognostic (2.21e-2)" "unprognostic (1.28e-1)" "unprognostic (2.12e-1)" SKIC3 "KIAA0372, SKI3, THES, TTC37" ENSG00000198677 "SKI3 subunit of superkiller complex" Q6PGP7 5 95461755-95555050 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037905 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 7: Non-specific - Transcription" 31 Nucleoplasm Cytosol "HPA037905: " "unprognostic (2.65e-1)" "unprognostic (2.40e-2)" "unprognostic (2.14e-1)" "unprognostic (5.11e-2)" "unprognostic (7.25e-3)" "unprognostic (1.06e-1)" "unprognostic (1.03e-1)" "unprognostic (8.04e-2)" "unprognostic (2.31e-1)" "unprognostic (3.77e-2)" "potential prognostic favorable (1.23e-6)" "unprognostic (6.17e-2)" "unprognostic (1.60e-1)" "unprognostic (1.39e-2)" "unprognostic (2.61e-1)" "unprognostic (1.36e-1)" "unprognostic (2.06e-1)" "unprognostic (4.16e-2)" "unprognostic (3.32e-2)" "unprognostic (7.68e-2)" "unprognostic (1.62e-2)" "unprognostic (6.05e-2)" "unprognostic (3.09e-2)" "unprognostic (2.33e-1)" "unprognostic (1.21e-2)" "unprognostic (1.62e-1)" "unprognostic (1.84e-1)" "unprognostic (6.17e-3)" "unprognostic (2.27e-1)" "unprognostic (7.60e-2)" "unprognostic (1.89e-1)" SKIC8 "REC14, SKI8, WDR61" ENSG00000140395 "SKI8 subunit of superkiller complex" Q9GZS3 15 78277835-78299703 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 226.5;Late primary spermatocytes: 224.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039932, HPA040065" Enhanced Enhanced Nucleoplasm,Cytosol NA NA 35000 "Cluster 13: Non-specific - Mitochondria" "Cluster 22: Epididymis - Mixed function" "Cluster 55: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 75: Non-specific - Chaperones and protein folding" 116 "Nucleoplasm, Cytosol" "HPA039932: , HPA040065: " "unprognostic (7.41e-2)" "unprognostic (9.16e-2)" "unprognostic (3.38e-2)" "unprognostic (8.56e-2)" "unprognostic (9.77e-2)" "potential prognostic favorable (5.15e-4)" "unprognostic (2.17e-1)" "unprognostic (2.37e-1)" "unprognostic (1.09e-1)" "unprognostic (6.81e-2)" "potential prognostic favorable (2.79e-9)" "unprognostic (8.37e-3)" "unprognostic (4.69e-3)" "unprognostic (2.43e-1)" "potential prognostic unfavorable (1.11e-5)" "unprognostic (1.13e-1)" "unprognostic (1.51e-1)" "unprognostic (2.45e-3)" "unprognostic (3.24e-2)" "unprognostic (7.54e-3)" "unprognostic (3.07e-1)" "unprognostic (2.00e-1)" "unprognostic (1.50e-1)" "unprognostic (3.73e-1)" "unprognostic (3.55e-2)" "unprognostic (6.45e-2)" "unprognostic (5.05e-2)" "unprognostic (2.28e-2)" "unprognostic (3.13e-1)" "unprognostic (2.85e-1)" "unprognostic (1.21e-2)" SKIDA1 "C10orf140, FLJ45187" ENSG00000180592 "SKI/DACH domain containing 1" Q1XH10 10 21513475-21526368 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 15.7;Early spermatids: 22.0;Hepatocytes: 13.2;Late spermatids: 26.2;Retinal bipolar cells: 17.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 7.2" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039208, HPA040439" Uncertain Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 76: Non-specific - Metabolism" "Cluster 53: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 1 "Nuclear bodies" "Nucleoplasm, Cytosol" "HPA039208: , HPA040439: " "unprognostic (8.20e-2)" "unprognostic (4.02e-3)" "unprognostic (3.37e-1)" "unprognostic (1.81e-1)" "unprognostic (7.05e-2)" SKIL "SNO, SnoA, SnoN" ENSG00000136603 "SKI like proto-oncogene" P12757 3 170357342-170396835 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 970.4;Urothelial cells: 463.8" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 307.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008472, HPA014233" Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 39: Astrocytes - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 31 Nucleoplasm Cytosol "HPA008472: , HPA014233: " "unprognostic (1.06e-1)" "unprognostic (9.88e-2)" "unprognostic (1.68e-1)" "potential prognostic unfavorable (2.42e-4)" "unprognostic (1.39e-1)" "unprognostic (3.06e-1)" "unprognostic (4.48e-1)" "unprognostic (1.99e-1)" "unprognostic (7.76e-2)" "potential prognostic unfavorable (5.80e-5)" "unprognostic (2.23e-2)" "unprognostic (6.81e-2)" "unprognostic (6.45e-2)" "unprognostic (1.38e-2)" "unprognostic (4.22e-2)" "unprognostic (1.58e-2)" "unprognostic (4.15e-1)" "unprognostic (1.61e-1)" "unprognostic (1.92e-1)" "unprognostic (2.51e-1)" "potential prognostic unfavorable (1.01e-4)" "unprognostic (7.57e-3)" "unprognostic (8.56e-3)" "unprognostic (1.38e-2)" "unprognostic (1.05e-1)" "unprognostic (2.59e-1)" "unprognostic (1.45e-1)" "unprognostic (2.32e-2)" "unprognostic (1.14e-1)" "unprognostic (2.91e-2)" "unprognostic (1.86e-2)" SKOR1 "CORL1, FUSSEL15, LBXCOR1" ENSG00000188779 "SKI family transcriptional corepressor 1" P84550 15 67819704-67834582 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 8.3" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 4.1;Gonadotrophs: 2.7;Late spermatids: 3.4;Retinal horizontal cells: 2.0;Thymic myoid cells: 1.4;Thyrotrophs: 1.4" "Cell type enriched" "Detected in some" 6 "cerebellar inhibitory: 10.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "Rhabdoid: 4.1" "Group enriched" "Detected in some" 11 "cerebellum: 3.7;pons and medulla: 1.2" "Region enriched" "Detected in some" 5 "cerebellum: 6.6" "HPA040673, HPA071150" Enhanced Approved Nucleoplasm NA NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 24: Non-specific - Unknown function" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" Nucleoplasm "HPA040673: , HPA071150: " "potential prognostic favorable (5.28e-6)" SKOR2 "CORL2, Fussel-18, FUSSEL18" ENSG00000215474 "SKI family transcriptional corepressor 2" Q2VWA4 18 47206169-47251660 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 6.5;Early primary spermatocytes: 15.4;Late primary spermatocytes: 1.9;Late spermatids: 2.2;Other brain neurons: 1.3;Retinal bipolar cells: 6.4;Undifferentiated spermatogonia: 3.6" "Cell type enriched" "Detected in single" 26 "splatter: 5.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "cerebellum: 2.4" "Not detected" "Not detected" HPA046206 Uncertain NA NA "Cluster 43: Hindbrain - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "HPA046206: " SKP1 "EMC19, MGC34403, OCP-II, OCP2, p19A, SKP1A, TCEB1L" ENSG00000113558 "S-phase kinase associated protein 1" P63208 5 134148935-134176964 "Essential proteins, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB012982, HPA053745" Approved Approved "Nucleoplasm,Cytokinetic bridge,Primary cilium,Centrosome,Basal body,Cytosol" Yes No 1400000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 98: Neurons - Neurotransmission & signaling" 334 "Nucleoplasm, Cytosol" "Cytokinetic bridge, Primary cilium, Centrosome, Basal body" "CAB012982: , HPA053745: " "unprognostic (8.49e-2)" "unprognostic (2.63e-3)" "unprognostic (8.06e-3)" "unprognostic (2.35e-1)" "unprognostic (1.17e-2)" "unprognostic (3.81e-3)" "unprognostic (4.67e-2)" "unprognostic (6.78e-2)" "unprognostic (2.53e-3)" "unprognostic (8.29e-2)" "potential prognostic favorable (1.85e-9)" "unprognostic (5.96e-3)" "unprognostic (2.26e-1)" "unprognostic (1.06e-3)" "unprognostic (3.28e-2)" "unprognostic (3.11e-2)" "unprognostic (1.72e-2)" "unprognostic (7.29e-2)" "unprognostic (1.09e-2)" "unprognostic (1.73e-1)" "unprognostic (1.16e-2)" "unprognostic (1.01e-1)" "unprognostic (9.97e-2)" "unprognostic (1.84e-2)" "unprognostic (2.97e-2)" "unprognostic (9.58e-3)" "unprognostic (1.83e-1)" "unprognostic (6.85e-3)" "unprognostic (1.96e-1)" "unprognostic (1.99e-1)" "unprognostic (5.45e-2)" SKP2 "FBL1, FBXL1, p45" ENSG00000145604 "S-phase kinase associated protein 2" Q13309 5 36151989-36196849 "Cancer-related genes, Essential proteins, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity, Ubl conjugation pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 35.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 176.7;Extravillous trophoblasts: 277.9;Hepatocytes: 192.6;Migrating cytotrophoblasts: 236.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013491, CAB013533, HPA051196, HPA054633" Approved Supported Nucleoplasm,Nucleoli,Cytosol NA Yes "Cluster 46: Basophils - Proteolysis" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 53: Neurons - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 130 "Nucleoplasm, Cytosol" Nucleoli "CAB013491: , CAB013533: , HPA051196: , HPA054633: " "unprognostic (6.97e-2)" "unprognostic (7.77e-2)" "unprognostic (1.81e-1)" "unprognostic (5.65e-2)" "unprognostic (5.21e-2)" "unprognostic (3.14e-1)" "unprognostic (4.06e-1)" "unprognostic (3.91e-2)" "unprognostic (1.42e-2)" "unprognostic (1.04e-3)" "unprognostic (1.43e-1)" "unprognostic (4.91e-2)" "unprognostic (9.51e-2)" "potential prognostic unfavorable (3.04e-4)" "unprognostic (6.81e-2)" "unprognostic (2.59e-2)" "unprognostic (4.02e-3)" "unprognostic (5.58e-2)" "potential prognostic favorable (6.73e-5)" "unprognostic (5.82e-2)" "unprognostic (2.68e-2)" "unprognostic (3.39e-3)" "unprognostic (2.39e-2)" "unprognostic (8.58e-2)" "unprognostic (8.22e-3)" "unprognostic (2.31e-1)" "potential prognostic unfavorable (1.64e-5)" "unprognostic (8.56e-3)" "unprognostic (2.00e-2)" "unprognostic (1.19e-1)" "unprognostic (9.70e-2)" SLA "hSLAP, SLA1, SLAP, SLAP-1" ENSG00000155926 "Src like adaptor" Q13239 8 133036728-133102912 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 92.1;lymphoid tissue: 145.7" "Cell type enriched" "Detected in many" 4 "Neutrophils: 1982.6" "Group enriched" "Detected in many" 5 "central nervous system macrophage: 148.2;hippocampal dentate gyrus: 44.9;leukocyte: 174.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 9 "Leukemia: 36.7;lymphoma: 22.5;Myeloma: 17.4" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Heart muscle - Macrophages, Lung - Neutrophils_2, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012296, HPA074192" Enhanced Approved "Nuclear membrane,Cytosol" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 9 "Nuclear membrane, Cytosol" "HPA012296: , HPA074192: " "unprognostic (1.12e-2)" "unprognostic (1.65e-2)" "unprognostic (7.37e-3)" "unprognostic (2.74e-3)" "unprognostic (9.91e-2)" "unprognostic (2.49e-2)" "unprognostic (4.90e-2)" "unprognostic (1.79e-1)" "unprognostic (1.14e-2)" "unprognostic (2.39e-1)" "unprognostic (3.14e-2)" "unprognostic (3.06e-1)" "unprognostic (2.28e-1)" "unprognostic (1.25e-1)" "unprognostic (2.39e-2)" "unprognostic (1.94e-3)" "unprognostic (9.12e-2)" "unprognostic (1.32e-1)" "unprognostic (1.68e-1)" "unprognostic (2.81e-2)" "unprognostic (3.02e-1)" "unprognostic (3.01e-2)" "unprognostic (1.07e-1)" "unprognostic (4.57e-1)" "unprognostic (1.15e-1)" "unprognostic (3.88e-3)" "unprognostic (3.10e-2)" "unprognostic (3.92e-1)" "unprognostic (4.44e-2)" "unprognostic (1.97e-1)" "unprognostic (7.81e-2)" SLA2 "C20orf156, FLJ21992, SLAP-2" ENSG00000101082 "Src like adaptor 2" Q9H6Q3 20 36612318-36646196 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 11.7;lymphoid tissue: 17.0" "Cell type enhanced" "Detected in many" "Megakaryocyte progenitors: 69.8;Megakaryocytes: 166.9;NK-cells: 257.5;pDCs: 96.7;Platelets: 447.0;T-cells: 124.3;Thymocytes: 45.7" "Cell type enriched" "Detected in many" 11 "leukocyte: 76.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "gdT-cell: 28.8;MAIT T-cell: 24.1;memory CD4 T-cell: 23.8;memory CD8 T-cell: 27.0;naive CD4 T-cell: 21.8;naive CD8 T-cell: 30.5;NK-cell: 39.2;plasmacytoid DC: 48.4;T-reg: 33.4" "Group enriched" "Detected in many" 8 "dendritic cells: 48.4;NK-cells: 39.2;T-cells: 33.4" "Cancer enriched" "Detected in some" 9 "Leukemia: 15.2" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Lung - NK-cells (Lung), Minor Salivary Gland - T-cells, Prostate - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA053746, HPA058217" Approved "Nucleoplasm,Golgi apparatus,Vesicles" No NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 6 "Nucleoplasm, Golgi apparatus, Vesicles" "HPA053746: , HPA058217: " "unprognostic (8.65e-2)" "unprognostic (3.28e-3)" "unprognostic (7.87e-2)" "potential prognostic favorable (1.07e-4)" "unprognostic (1.51e-1)" "unprognostic (5.18e-2)" "unprognostic (1.55e-1)" "unprognostic (3.74e-3)" "unprognostic (3.17e-2)" "unprognostic (2.45e-1)" "unprognostic (1.18e-1)" "unprognostic (3.55e-2)" "unprognostic (2.95e-3)" "unprognostic (6.30e-2)" "unprognostic (1.70e-1)" "unprognostic (7.38e-2)" "unprognostic (1.07e-2)" "unprognostic (8.53e-2)" "unprognostic (4.64e-2)" "unprognostic (1.40e-3)" "unprognostic (2.09e-1)" "unprognostic (9.01e-2)" "unprognostic (9.16e-2)" "unprognostic (5.29e-2)" "unprognostic (2.69e-2)" "unprognostic (3.26e-2)" SLAIN1 "C13orf32, FLJ30046" ENSG00000139737 "SLAIN motif family member 1" Q8ND83 13 77697687-77764242 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "brain: 334.8" "Cell type enhanced" "Detected in many" "Müller glia: 246.3;Oligodendrocyte progenitor cells: 349.4;Oligodendrocytes: 1223.5;Sertoli cells: 219.8" "Cell type enhanced" "Detected in all" "oligodendrocyte: 1777.8" "Cancer enriched" "Detected in all" 4 "Glioblastoma Multiforme (TCGA): 96.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Bone cancer: 55.4;Myeloma: 57.0" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Pituitary gland - Undifferentiated cells (Pituitary gland)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 6: Leukemia - Signal transduction" "Cluster 80: Oligodendrocytes - Myelination" 36 "unprognostic (1.05e-2)" "potential prognostic favorable (3.54e-5)" "unprognostic (1.45e-1)" "unprognostic (2.06e-2)" "unprognostic (5.67e-2)" "unprognostic (8.78e-2)" "unprognostic (3.07e-1)" "unprognostic (3.83e-2)" "unprognostic (1.64e-3)" "unprognostic (7.63e-2)" "unprognostic (1.83e-1)" "unprognostic (5.80e-3)" "unprognostic (2.23e-3)" "unprognostic (1.50e-1)" "unprognostic (7.63e-2)" "unprognostic (3.37e-2)" "unprognostic (2.02e-1)" "unprognostic (9.22e-2)" "unprognostic (2.63e-2)" "unprognostic (8.06e-2)" "unprognostic (4.94e-2)" "unprognostic (1.95e-2)" "unprognostic (2.83e-2)" "potential prognostic unfavorable (7.77e-4)" "unprognostic (2.82e-1)" "unprognostic (1.87e-1)" "unprognostic (9.99e-2)" "unprognostic (1.41e-2)" "unprognostic (1.47e-2)" "unprognostic (1.34e-1)" "unprognostic (1.35e-1)" SLAIN2 "FLJ21611, KIAA1458" ENSG00000109171 "SLAIN motif family member 2" Q9P270 4 48341529-48426201 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 563.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035824, HPA063599" Approved Supported "Primary cilium tip,Centrosome,Basal body,Cytosol" NA NA 96000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 16: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 24 "Centrosome, Cytosol" "Primary cilium tip, Basal body" "HPA035824: , HPA063599: " "unprognostic (2.28e-1)" "unprognostic (3.03e-2)" "unprognostic (1.20e-1)" "unprognostic (2.25e-3)" "unprognostic (1.96e-2)" "unprognostic (1.29e-1)" "unprognostic (2.64e-1)" "unprognostic (9.19e-3)" "unprognostic (9.49e-2)" "potential prognostic unfavorable (4.06e-5)" "validated prognostic favorable (1.63e-6)" "validated prognostic favorable (8.85e-5)" "unprognostic (7.10e-2)" "unprognostic (8.47e-2)" "unprognostic (1.86e-1)" "unprognostic (2.41e-1)" "unprognostic (9.28e-3)" "unprognostic (3.28e-1)" "unprognostic (4.42e-1)" "unprognostic (5.81e-2)" "unprognostic (8.99e-2)" "unprognostic (2.77e-3)" "unprognostic (4.86e-2)" "unprognostic (1.42e-1)" "unprognostic (1.22e-1)" "unprognostic (1.95e-1)" "unprognostic (2.02e-1)" "unprognostic (1.61e-1)" "unprognostic (3.68e-1)" "unprognostic (9.26e-2)" "unprognostic (1.65e-1)" SLAMF1 "CD150, SLAM" ENSG00000117090 "Signaling lymphocytic activation molecule family member 1" Q13291 1 160608106-160647044 "CD markers, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Cell adhesion, Host-virus interaction, Immunity, Innate immunity, Phagocytosis" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "lymphoid tissue: 59.1" "Cell type enhanced" "Detected in some" "B-cells: 43.2;cDC: 15.1;Innate lymphoid cells: 55.0;Late spermatids: 14.8;Macrophages: 17.6;Mast cells: 28.9;monocytes: 43.1;Plasma cells: 133.4;T-cells: 93.9" "Cell type enriched" "Detected in single" 120 "leukocyte: 89.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 51.2;T-reg: 49.0" "Group enriched" "Detected in many" 16 "B-cells: 17.9;T-cells: 51.2" "Cancer enhanced" "Detected in some" "Leukemia: 14.5;lymphoma: 35.8" "Adipose subcutaneous - T-cells, Liver - T-cells, Prostate - T-cells, Skin - T-cells, Spleen - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002438, HPA069319" Enhanced "Secreted to blood" Receptor NA NA 61000 "Cluster 16: Non-specific - Cell proliferation" "Cluster 80: Thymus - Adaptive immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 78: Plasma cells - Antibody production & ER-stress response" 7 "CAB002438: , HPA069319: " "unprognostic (6.04e-2)" "unprognostic (1.08e-2)" "unprognostic (8.02e-2)" "potential prognostic favorable (7.93e-4)" "unprognostic (1.30e-1)" "unprognostic (2.72e-2)" "potential prognostic favorable (3.16e-5)" "unprognostic (7.44e-2)" "unprognostic (1.69e-1)" "unprognostic (6.33e-3)" "potential prognostic favorable (6.60e-6)" "unprognostic (2.40e-2)" "unprognostic (2.26e-1)" "unprognostic (1.94e-1)" "unprognostic (1.07e-1)" "unprognostic (4.14e-1)" "unprognostic (1.16e-2)" "unprognostic (4.50e-2)" "unprognostic (9.16e-2)" "unprognostic (3.13e-1)" "unprognostic (4.50e-2)" SLAMF6 "CD352, KALI, KALIb, Ly108, NTB-A, NTBA, SF2000" ENSG00000162739 "SLAM family member 6" Q96DU3 1 160485030-160523262 "CD markers, Predicted membrane proteins" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 57.7" "Cell type enhanced" "Detected in some" "B-cells: 63.4;Innate lymphoid cells: 37.8;Late spermatids: 29.3;NK-cells: 109.7;Plasma cells: 20.3;T-cells: 136.4" "Cell type enriched" "Detected in some" 98 "leukocyte: 147.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Leukemia: 10.0;lymphoma: 35.7" "Adipose subcutaneous - T-cells, Adrenal gland - T-cells, Colon - T-cells, Liver - T-cells, Lung - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Spleen - B-cells (Spleen), Stomach - T-cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA051363, HPA051903" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 9: T-cells - Adaptive immunity: Regulation" 6 "Plasma membrane, Cytosol" "HPA051363: , HPA051903: " "unprognostic (1.18e-2)" "unprognostic (1.66e-3)" "unprognostic (1.85e-2)" "unprognostic (8.99e-2)" "unprognostic (2.90e-1)" "unprognostic (1.39e-1)" "unprognostic (1.50e-1)" "potential prognostic favorable (1.25e-4)" "unprognostic (2.92e-2)" "unprognostic (2.42e-1)" "unprognostic (3.48e-3)" "unprognostic (4.20e-3)" "unprognostic (5.08e-3)" "unprognostic (6.66e-3)" "unprognostic (5.50e-2)" "unprognostic (3.06e-2)" "unprognostic (1.31e-1)" "unprognostic (2.44e-2)" "unprognostic (1.03e-1)" "unprognostic (9.99e-2)" "unprognostic (1.22e-1)" "unprognostic (6.03e-2)" "unprognostic (5.11e-2)" "unprognostic (2.12e-2)" "unprognostic (4.03e-1)" "unprognostic (2.84e-1)" "unprognostic (1.18e-1)" "unprognostic (4.33e-1)" SLAMF7 "19A, CD319, CRACC, CS1" ENSG00000026751 "SLAM family member 7" Q9NQ25 1 160739057-160754821 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Innate immunity" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 30.5;lymphoid tissue: 58.0;stomach 1: 32.1" "Cell type enhanced" "Detected in some" "cDC: 96.4;Macrophages: 38.5;monocytes: 30.5;Neutrophils: 30.7;NK-cells: 101.0;pDCs: 159.1;Plasma cells: 395.3;T-cells: 51.3" "Cell type enriched" "Detected in single" 239 "leukocyte: 94.0" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 43.5" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in many" 5 "Myeloma: 188.3" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Heart muscle - T-cells, Liver - T-cells, Minor Salivary Gland - Plasma cells, Pituitary gland - T-cells, Prostate - T-cells, Stomach - Plasma cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB015445, HPA055945, HPA061654" Enhanced Approved Vesicles NA NA 94000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 44: Plasma cells - Antibody production & secretion" Vesicles "CAB015445: , HPA055945: , HPA061654: " "unprognostic (9.26e-2)" "unprognostic (1.14e-2)" "unprognostic (2.59e-1)" "unprognostic (1.49e-1)" "unprognostic (4.62e-2)" "unprognostic (2.36e-1)" "unprognostic (1.08e-1)" "unprognostic (1.42e-1)" "unprognostic (2.51e-2)" "unprognostic (2.60e-1)" "unprognostic (9.09e-3)" "unprognostic (3.40e-1)" "unprognostic (1.32e-2)" "unprognostic (1.43e-1)" "unprognostic (1.35e-2)" "unprognostic (7.07e-2)" "unprognostic (2.84e-3)" "unprognostic (2.01e-1)" "unprognostic (2.78e-1)" "potential prognostic favorable (8.21e-4)" "unprognostic (4.02e-2)" "unprognostic (1.77e-1)" "unprognostic (4.27e-2)" "unprognostic (3.85e-1)" "unprognostic (3.75e-3)" "unprognostic (3.29e-1)" "unprognostic (5.58e-3)" "unprognostic (3.98e-1)" "unprognostic (3.98e-2)" "unprognostic (7.90e-2)" "unprognostic (2.00e-1)" SLAMF8 "BLAME, CD353, SBBI42" ENSG00000158714 "SLAM family member 8" Q9P0V8 1 159826811-159837492 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 30.8" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 17.8;cDC: 66.3;Epicardial cells: 6.8;Hofbauer cells: 12.1;Kupffer cells: 13.3;Macrophages: 37.7;monocytes: 13.2" "Cell type enhanced" "Detected in some" "ependymal cell: 2.0;leukocyte: 2.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "myeloid DC: 14.3" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 5 "Leukemia: 1.4;lymphoma: 2.9" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Heart muscle - Macrophages, Lung - Macrophages, Minor Salivary Gland - Macrophages, Skeletal muscle - Fibroblasts, Spleen - Macrophages, Stomach - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA067601 Enhanced NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 82: Dendritic cells - Antigen presentation" 9 "HPA067601: " "unprognostic (1.64e-2)" "unprognostic (1.74e-1)" "unprognostic (2.51e-1)" "unprognostic (1.86e-2)" "unprognostic (1.12e-1)" "unprognostic (1.57e-1)" "unprognostic (9.21e-3)" "unprognostic (2.11e-2)" "unprognostic (2.58e-2)" "unprognostic (1.54e-1)" "unprognostic (2.74e-2)" "unprognostic (1.26e-1)" "unprognostic (1.93e-1)" "unprognostic (1.16e-1)" "unprognostic (3.47e-1)" "unprognostic (1.79e-1)" "unprognostic (1.61e-2)" "unprognostic (2.33e-1)" "unprognostic (1.82e-1)" "unprognostic (2.39e-1)" "unprognostic (2.04e-1)" "unprognostic (1.67e-1)" "unprognostic (5.87e-2)" "unprognostic (1.90e-1)" "unprognostic (3.16e-2)" "unprognostic (7.38e-2)" "potential prognostic favorable (7.44e-4)" "unprognostic (1.90e-1)" "unprognostic (5.36e-2)" "unprognostic (1.63e-1)" "unprognostic (5.26e-1)" SLAMF9 "CD2F-10, CD84-H1, SF2001" ENSG00000162723 "SLAM family member 9" Q96A28 1 159951492-159954237 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "cDC: 21.5;Early spermatids: 12.6;Hepatocytes: 3.5;Late spermatids: 63.7;Macrophages: 4.9" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 8 "myeloid DC: 2.1" "Lineage enriched" "Detected in single" 8 "dendritic cells: 2.1" "Cancer enriched" "Detected in some" 7 "skin cancer: 8.1" "Testis - Late spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA035153 Uncertain NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 69: Skin cancer - ECM organization" "Cluster 82: Dendritic cells - Antigen presentation" "HPA035153: " "unprognostic (2.74e-1)" "unprognostic (3.21e-1)" "unprognostic (2.52e-2)" "unprognostic (3.04e-2)" "unprognostic (4.87e-2)" "unprognostic (3.06e-1)" "unprognostic (8.75e-3)" "potential prognostic unfavorable (2.09e-6)" "unprognostic (7.24e-2)" "unprognostic (4.43e-1)" "unprognostic (9.77e-2)" "unprognostic (2.03e-1)" SLBP HBP ENSG00000163950 "Stem-loop binding protein" Q14493 4 1692731-1712344 "Essential proteins, Predicted intracellular proteins" "mRNA processing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 382.6;Early primary spermatocytes: 367.7;Oocytes: 419.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019254, HPA061670" Supported Supported Nucleoplasm,Nucleoli,Cytosol Yes Yes "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 14: Neurons - Synaptic function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 75: Non-specific - Chaperones and protein folding" 25 "Nucleoplasm, Nucleoli" Cytosol "HPA019254: , HPA061670: " "unprognostic (2.68e-3)" "unprognostic (1.46e-2)" "unprognostic (7.44e-2)" "unprognostic (3.26e-1)" "unprognostic (1.03e-1)" "unprognostic (1.20e-1)" "unprognostic (6.43e-2)" "unprognostic (2.70e-1)" "unprognostic (7.43e-3)" "unprognostic (3.19e-2)" "potential prognostic favorable (3.31e-5)" "unprognostic (2.71e-2)" "unprognostic (1.29e-3)" "validated prognostic unfavorable (8.19e-5)" "validated prognostic unfavorable (3.88e-5)" "unprognostic (3.49e-3)" "potential prognostic unfavorable (1.36e-4)" "unprognostic (1.69e-1)" "unprognostic (2.04e-1)" "unprognostic (2.51e-1)" "unprognostic (8.99e-3)" "unprognostic (1.68e-2)" "unprognostic (1.44e-1)" "potential prognostic unfavorable (5.75e-4)" "unprognostic (1.83e-2)" "unprognostic (8.72e-2)" "unprognostic (3.06e-3)" "unprognostic (1.61e-1)" "unprognostic (1.83e-1)" "unprognostic (3.84e-1)" "unprognostic (3.46e-2)" SLC10A1 "NTCP, NTCP1" ENSG00000100652 "Solute carrier family 10 member 1" Q14973 14 69775416-69797241 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Host-virus interaction, Ion transport, Lipid transport, Sodium transport, Symport, Transport" "Host cell receptor for virus entry, Receptor" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1060 "liver: 399.1" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 67.2;Epicardial cells: 109.2;Hepatocytes: 217.0;Thymocytes: 64.4" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in single" 343 "Liver Hepatocellular Carcinoma (TCGA): 84.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA042727 Approved NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 15: Non-specific - Transcription" "Cluster 34: Testis cancer - Unknown function" "Cluster 20: Non-specific - Transcription regulation" 85 "HPA042727: " "validated prognostic favorable (3.68e-6)" "validated prognostic favorable (1.61e-6)" "potential prognostic unfavorable (3.28e-5)" SLC10A2 "ASBT, IBAT, ISBT, NTCP2" ENSG00000125255 "Solute carrier family 10 member 2" Q12908 13 103043998-103066417 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Lipid transport, Sodium transport, Symport, Transport" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "intestine: 89.4" "Cell type enriched" "Detected in some" 15 "Enterocytes: 431.9" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Kidney Renal Clear Cell Carcinoma (TCGA): 9.4;Kidney Renal Papillary Cell Carcinoma (TCGA): 4.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "ovarian cancer: 2.5" "Kidney - Proximal tubular cells, Pituitary gland - Thyrotropes" "Not detected" "Not detected" "Not detected" "Not detected" HPA004795 Approved NA NA "Cluster 77: Intestine - Digestion" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 1: Enterocytes - Absorption and Digestion" 14 "HPA004795: " "validated prognostic favorable (2.86e-11)" "validated prognostic favorable (3.01e-5)" "unprognostic (4.13e-2)" SLC10A3 "DXS253E, P3" ENSG00000126903 "Solute carrier family 10 member 3" P09131 X 154487306-154490690 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 52.4;Epididymal principal cells: 59.8;Esophageal apical cells: 77.6;Esophageal suprabasal cells: 53.2;Extravillous trophoblasts: 79.8;Migrating cytotrophoblasts: 63.7;Platelets: 146.5;Syncytiotrophoblasts: 118.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 10 "basophil: 218.9" "Lineage enriched" "Detected in all" 17 "granulocytes: 218.9" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021656 Approved Approved "Intermediate filaments" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 54: Non-specific - Ribosome" "Cluster 18: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" "Intermediate filaments" "HPA021656: " "unprognostic (1.91e-1)" "unprognostic (2.63e-2)" "unprognostic (1.26e-2)" "unprognostic (6.78e-2)" "unprognostic (8.21e-3)" "unprognostic (1.98e-1)" "unprognostic (2.23e-3)" "unprognostic (3.12e-2)" "unprognostic (1.35e-1)" "unprognostic (1.53e-1)" "unprognostic (2.69e-2)" "unprognostic (6.81e-2)" "unprognostic (1.94e-2)" "unprognostic (3.23e-3)" "potential prognostic unfavorable (5.41e-4)" "unprognostic (1.03e-2)" "unprognostic (4.15e-2)" "unprognostic (8.25e-2)" "unprognostic (3.57e-1)" "unprognostic (1.30e-1)" "unprognostic (1.31e-2)" "unprognostic (3.40e-3)" "unprognostic (1.22e-1)" "unprognostic (1.70e-1)" "unprognostic (1.61e-1)" "unprognostic (2.05e-1)" "unprognostic (6.13e-2)" "unprognostic (8.36e-2)" "unprognostic (8.90e-2)" "unprognostic (8.39e-3)" "unprognostic (1.05e-1)" SLC10A4 MGC29802 ENSG00000145248 "Solute carrier family 10 member 4" Q96EP9 4 48483343-48489526 "Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.8;pituitary gland: 5.0" "Cell type enhanced" "Detected in some" "Brain inhibitory neurons: 9.3;Erythrocyte progenitors: 19.0;Gonadotrophs: 5.9;Late spermatids: 7.0;Megakaryocyte-Erythroid progenitors: 8.4;Oocytes: 9.2;Other brain neurons: 39.3;Retinal amacrine cells: 6.9;Salivary myoepithelial cells: 9.4;Thyrotrophs: 33.9" "Cell type enriched" "Detected in many" 5 "CGE interneuron: 42.9" "Cancer enriched" "Detected in single" 9 "Glioblastoma Multiforme (TCGA): 7.6" "Region enhanced" "Detected in many" "midbrain: 79.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 11 "Adrenocortical cancer: 23.7;Neuroblastoma: 50.9" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pituitary gland - Thyrotropes, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "basal ganglia: 22.4;midbrain: 88.3;pons: 36.8;spinal cord: 70.0" HPA028835 Uncertain Supported NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 4 "HPA028835: " "unprognostic (3.44e-2)" "unprognostic (1.86e-1)" "potential prognostic unfavorable (1.56e-4)" SLC10A5 ENSG00000253598 "Solute carrier family 10 member 5" Q5PT55 8 81693631-81695058 "Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 3.7;liver: 10.6" "Cell type enhanced" "Detected in some" "Colonocytes: 5.1;Enterocytes: 6.6;Esophageal apical cells: 6.9;Foveolar cells: 10.6;Goblet cells: 2.7;Hematopoietic stem cells: 3.9;Prostatic club cells: 2.7;Proximal tubule cells: 5.7;Respiratory secretory cells: 3.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Liver - Hepatocytes, Stomach - Gastric mucous cells" "Not detected" "Not detected" HPA025966 Uncertain Approved "Nucleoplasm,Nuclear bodies,Plasma membrane" NA NA "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 37: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 68: Foveolar cells - Mucosal defense" "Nucleoplasm, Nuclear bodies, Plasma membrane" "HPA025966: " "unprognostic (5.32e-2)" "unprognostic (4.01e-2)" "unprognostic (8.21e-3)" "potential prognostic favorable (5.83e-5)" "unprognostic (6.04e-2)" "unprognostic (1.50e-2)" "unprognostic (2.04e-2)" "unprognostic (1.64e-1)" "unprognostic (5.68e-3)" "unprognostic (1.76e-1)" SLC10A6 SOAT ENSG00000145283 "Solute carrier family 10 member 6" Q3KNW5 4 86823468-86849384 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Lipid transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 8.5;skin 1: 12.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 51.0;Early spermatids: 94.4;Endometrial luminal cells: 43.8;Esophageal apical cells: 80.0;Esophageal suprabasal cells: 37.8;Late spermatids: 322.4;Suprabasal keratinocytes: 116.7" "Cell type enhanced" "Detected in some" "ependymal cell: 5.5" "Cancer enhanced" "Detected in some" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 4.5;Head and Neck Squamous Cell Carcinoma (TCGA): 8.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "head and neck cancer: 1.0" "Colon - Endothelial cells, Minor Salivary Gland - Minor salivary gland basal cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA016662 Enhanced NA NA "Cluster 58: Skin - Keratinization" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 26: Keratinocytes - Keratinization" 124 "HPA016662: " "unprognostic (4.79e-2)" "unprognostic (2.82e-3)" "unprognostic (2.34e-2)" "unprognostic (4.94e-3)" "unprognostic (4.04e-2)" "validated prognostic favorable (5.11e-8)" "validated prognostic favorable (8.45e-5)" "unprognostic (2.87e-1)" "unprognostic (2.29e-2)" "unprognostic (2.02e-1)" SLC10A7 "C4orf13, DKFZp313H0531, DKFZp566M114, DKFZp779O2438, MGC25043" ENSG00000120519 "Solute carrier family 10 member 7" Q0GE19 4 146253975-146522372 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Amelogenesis imperfecta, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039996 Uncertain NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 22: Epididymis - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 7: Non-specific - Transcription" 3 "HPA039996: " "unprognostic (4.43e-3)" "unprognostic (5.35e-2)" "unprognostic (7.69e-2)" "unprognostic (2.59e-3)" "unprognostic (4.77e-2)" "unprognostic (1.80e-1)" "unprognostic (2.44e-1)" "unprognostic (1.76e-2)" "unprognostic (7.01e-2)" "unprognostic (9.62e-2)" "potential prognostic favorable (8.44e-5)" "unprognostic (2.79e-3)" "unprognostic (2.04e-1)" "unprognostic (4.60e-2)" "unprognostic (9.22e-2)" "unprognostic (1.73e-1)" "potential prognostic unfavorable (2.87e-4)" "unprognostic (3.27e-3)" "unprognostic (2.15e-1)" "unprognostic (2.32e-1)" "unprognostic (2.16e-2)" "unprognostic (3.98e-3)" "unprognostic (1.49e-2)" "unprognostic (2.05e-1)" "unprognostic (3.77e-2)" "unprognostic (3.39e-2)" "unprognostic (2.14e-1)" "unprognostic (1.89e-2)" "unprognostic (1.65e-1)" "unprognostic (5.68e-3)" "unprognostic (2.56e-1)" SLC11A1 "LSH, NRAMP, NRAMP1" ENSG00000018280 "Solute carrier family 11 member 1" P49279 2 218382029-218396894 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Iron transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 34.3;lung: 83.5;lymphoid tissue: 51.8" "Group enriched" "Detected in many" 6 "monocytes: 688.8;Neutrophils: 2203.5" "Group enriched" "Detected in many" 14 "central nervous system macrophage: 62.7;leukocyte: 52.7" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 11.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "classical monocyte: 6.1;intermediate monocyte: 4.5;myeloid DC: 1.9;neutrophil: 4.4;non-classical monocyte: 6.1" "Group enriched" "Detected in many" 11 "dendritic cells: 1.9;granulocytes: 4.4;monocytes: 6.1" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Colon - Neutrophils, Kidney - Macrophages, Liver - Neutrophils, Prostate - Macrophages, Skin - Macrophages, Spleen - Neutrophils_2, Thyroid gland - Neutrophils" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA029590, HPA050378, HPA068540" Uncertain Approved Nucleoli,Mitochondria NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 5: Spleen - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 47: Leukemia - Hemostasis" "Cluster 24: Neutrophils - Innate immunity signal integration" Mitochondria Nucleoli "HPA029590: , HPA050378: , HPA068540: " "unprognostic (4.80e-2)" "unprognostic (3.91e-2)" "unprognostic (5.65e-2)" "unprognostic (5.63e-2)" "unprognostic (1.38e-3)" "unprognostic (1.90e-1)" "unprognostic (9.60e-3)" "unprognostic (8.53e-2)" "unprognostic (3.03e-2)" "unprognostic (5.05e-2)" "potential prognostic unfavorable (7.18e-6)" "unprognostic (1.05e-1)" "unprognostic (2.14e-2)" "unprognostic (1.12e-1)" "unprognostic (6.99e-2)" "unprognostic (4.79e-2)" "unprognostic (1.97e-2)" "unprognostic (1.01e-1)" "unprognostic (3.37e-2)" "unprognostic (3.71e-1)" "unprognostic (2.64e-2)" "unprognostic (3.27e-3)" "unprognostic (1.32e-1)" "unprognostic (3.56e-2)" "unprognostic (5.05e-2)" "unprognostic (2.54e-2)" "unprognostic (2.49e-2)" "unprognostic (2.49e-3)" "unprognostic (2.19e-3)" SLC11A2 "DCT1, DMT-1, DMT1, FLJ37416, NRAMP2" ENSG00000110911 "Solute carrier family 11 member 2" P49281 12 50979401-51028566 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Iron transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032139, HPA032140" Uncertain Supported Mitochondria No No "Cluster 33: Non-specific - ATP binding" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 5 Mitochondria "HPA032139: , HPA032140: " "unprognostic (7.51e-2)" "unprognostic (7.35e-3)" "unprognostic (1.26e-1)" "unprognostic (6.82e-3)" "unprognostic (2.95e-1)" "unprognostic (1.07e-1)" "unprognostic (3.45e-1)" "unprognostic (1.11e-1)" "unprognostic (2.96e-1)" "unprognostic (2.44e-1)" "potential prognostic favorable (8.22e-4)" "unprognostic (6.77e-2)" "unprognostic (1.41e-2)" "unprognostic (5.21e-2)" "unprognostic (7.26e-2)" "unprognostic (6.94e-3)" "unprognostic (1.77e-1)" "unprognostic (5.98e-2)" "unprognostic (6.56e-2)" "unprognostic (4.15e-2)" "unprognostic (2.09e-2)" "unprognostic (1.18e-1)" "potential prognostic unfavorable (7.28e-4)" "unprognostic (1.85e-1)" "unprognostic (4.51e-3)" "unprognostic (6.79e-3)" "unprognostic (7.16e-2)" "unprognostic (1.25e-2)" "unprognostic (1.20e-1)" "unprognostic (1.07e-2)" "unprognostic (7.91e-2)" SLC12A1 "BSC, BSC-1, BSC1, CCC2, NKCC2" ENSG00000074803 "Solute carrier family 12 member 1" Q13621 15 48178438-48304078 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Symport, Transport" "Bartter syndrome, Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 826 "kidney: 664.4" "Cell type enriched" "Detected in many" 29 "Loop of henle epithelial cells: 3067.8" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Kidney Chromophobe (TCGA): 4.8;Kidney Renal Clear Cell Carcinoma (TCGA): 2.9;Kidney Renal Papillary Cell Carcinoma (TCGA): 6.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Ascending Loop of Henle cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA014967, HPA018107" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 1: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" Vesicles Nucleoplasm "HPA014967: , HPA018107: " "unprognostic (2.19e-2)" "unprognostic (3.67e-1)" "unprognostic (2.87e-2)" "unprognostic (1.49e-1)" "unprognostic (5.54e-2)" "unprognostic (4.81e-2)" SLC12A2 "BSC-2, BSC2, CCC1, NKCC1, PPP1R141" ENSG00000064651 "Solute carrier family 12 member 2" P55011 5 128083766-128189677 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Symport, Transport" "Deafness, Disease variant, FDA approved drug targets, Intellectual disability, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 71.2" "Cell type enhanced" "Detected in many" "Breast secretory cells: 601.9;Enteric stem cells: 983.9;Gastric chief cells: 741.5;Goblet cells: 688.5;Lacrimal acinar cells: 722.9;Mucous neck cells: 1033.7;Oligodendrocytes: 669.1;Paneth cells: 1001.7;Parietal cells: 601.1;Prostatic glandular cells: 761.8" "Cell type enhanced" "Detected in all" "oligodendrocyte: 848.9;pericyte: 922.1" "Cancer enhanced" "Detected in all" "Colon Adenocarcinoma (TCGA): 113.8;Rectum Adenocarcinoma (TCGA): 103.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 6.4" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "colorectal cancer: 106.3" "Adipose visceral - Endothelial cells, Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells (progenitors), Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020130, HPA063697" Approved Approved "Vesicles,Plasma membrane,Basal body" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 23 "Vesicles, Plasma membrane" "Basal body" "HPA020130: , HPA063697: " "unprognostic (5.65e-2)" "unprognostic (1.16e-1)" "unprognostic (8.40e-2)" "unprognostic (1.29e-1)" "unprognostic (3.45e-3)" "unprognostic (5.04e-3)" "unprognostic (1.94e-1)" "unprognostic (7.94e-2)" "unprognostic (5.03e-2)" "unprognostic (9.07e-3)" "validated prognostic favorable (2.01e-6)" "validated prognostic favorable (8.73e-4)" "unprognostic (1.69e-1)" "potential prognostic unfavorable (8.52e-4)" "unprognostic (1.96e-1)" "unprognostic (6.35e-2)" "unprognostic (1.74e-1)" "unprognostic (1.07e-1)" "unprognostic (2.96e-2)" "unprognostic (5.57e-2)" "unprognostic (5.83e-2)" "unprognostic (5.24e-2)" "unprognostic (1.45e-3)" "unprognostic (9.92e-2)" "unprognostic (1.12e-2)" "unprognostic (1.09e-1)" "unprognostic (1.19e-1)" "unprognostic (1.20e-1)" "unprognostic (2.95e-1)" "unprognostic (1.70e-1)" "potential prognostic favorable (2.68e-4)" SLC12A3 "NCC, NCCT" ENSG00000070915 "Solute carrier family 12 member 3" P55017 16 56865207-56915850 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 117 "kidney: 94.2" "Cell type enriched" "Detected in some" 19 "Distal convoluted tubule cells: 9100.1" "Low cell type specificity" "Detected in some" "Group enriched" "Detected in some" 5 "Kidney Renal Clear Cell Carcinoma (TCGA): 5.8;Kidney Renal Papillary Cell Carcinoma (TCGA): 9.1" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 20 "plasmacytoid DC: 14.9" "Lineage enriched" "Detected in single" 20 "dendritic cells: 14.9" "Cancer enhanced" "Detected in some" "ovarian cancer: 6.3;Uterine cancer: 6.7" "Kidney - Intercalated cells, Spleen - B-cells (Spleen)" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA028748 Enhanced NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 72: Kidney - Transmembrane transport" "Cluster 51: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 7 "HPA028748: " "unprognostic (3.28e-1)" "unprognostic (1.58e-1)" "unprognostic (4.10e-2)" "unprognostic (1.12e-2)" "unprognostic (1.27e-1)" "unprognostic (9.87e-3)" SLC12A4 KCC1 ENSG00000124067 "Solute carrier family 12 member 4" Q9UP95 16 67943474-67969601 "FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Symport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 52.1;Syncytiotrophoblasts: 81.3" "Cell type enhanced" "Detected in many" "Bergmann glia: 43.6;pericyte: 29.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041138, HPA048239" Approved Approved "Nucleoplasm,Cell Junctions,Cytokinetic bridge,Primary cilium" Yes NA "Cluster 33: Non-specific - ATP binding" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 18 "Nucleoplasm, Cell Junctions" "Cytokinetic bridge, Primary cilium" "HPA041138: , HPA048239: " "unprognostic (2.43e-3)" "unprognostic (5.42e-2)" "unprognostic (9.39e-2)" "unprognostic (1.46e-1)" "unprognostic (1.51e-1)" "unprognostic (1.74e-2)" "unprognostic (1.71e-1)" "unprognostic (1.58e-1)" "unprognostic (1.15e-2)" "unprognostic (5.54e-2)" "potential prognostic favorable (2.11e-8)" "unprognostic (1.23e-3)" "potential prognostic favorable (1.47e-4)" "unprognostic (1.13e-2)" "unprognostic (6.31e-3)" "unprognostic (9.70e-2)" "unprognostic (1.36e-1)" "unprognostic (1.60e-3)" "unprognostic (3.01e-1)" "unprognostic (2.60e-2)" "unprognostic (2.68e-1)" "unprognostic (2.60e-2)" "unprognostic (1.85e-2)" "unprognostic (4.19e-2)" "unprognostic (1.43e-1)" "unprognostic (2.69e-3)" "unprognostic (1.54e-1)" "unprognostic (3.29e-2)" "unprognostic (3.55e-1)" "unprognostic (1.72e-1)" "unprognostic (1.14e-1)" SLC12A5 "KCC2, KIAA1176" ENSG00000124140 "Solute carrier family 12 member 5" Q9H2X9 20 46021690-46060150 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Symport, Transport" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 194.7;retina: 109.4" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 89.5;Brain inhibitory neurons: 130.6;Cone photoreceptor cells: 198.7;Hofbauer cells: 42.8;Other brain neurons: 67.7;Pancreatic islet cells: 34.8;Retinal amacrine cells: 132.9;Retinal bipolar cells: 187.9;Rod photoreceptor cells: 118.2" "Cell type enhanced" "Detected in all" "midbrain-derived inhibitory: 289.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 2.4" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072058 Enhanced NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 27: Cerebellum - Synaptic function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 62: Non-specific - Plasma proteins" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "HPA072058: " "unprognostic (4.21e-2)" "unprognostic (1.55e-1)" "unprognostic (7.10e-2)" "unprognostic (4.87e-3)" "unprognostic (1.76e-1)" "potential prognostic unfavorable (5.70e-5)" "unprognostic (1.33e-1)" "unprognostic (1.38e-1)" "unprognostic (3.50e-1)" "validated prognostic unfavorable (2.79e-10)" "validated prognostic unfavorable (1.48e-4)" "unprognostic (3.00e-1)" "potential prognostic unfavorable (9.67e-4)" "unprognostic (1.54e-2)" "unprognostic (5.03e-2)" "unprognostic (1.84e-1)" "unprognostic (9.05e-2)" "unprognostic (3.11e-1)" "unprognostic (1.40e-3)" "unprognostic (7.13e-3)" "unprognostic (2.50e-1)" "unprognostic (5.81e-2)" "unprognostic (3.05e-1)" "unprognostic (6.65e-2)" "unprognostic (1.74e-1)" "unprognostic (3.46e-1)" "unprognostic (2.44e-1)" SLC12A6 "ACCPN, KCC3, KCC3A, KCC3B" ENSG00000140199 "Solute carrier family 12 member 6" Q9UHW9 15 34229784-34338060 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Symport, Transport" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Neutrophils: 2078.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 15.2;neutrophil: 23.5" "Lineage enriched" "Detected in many" 7 "granulocytes: 23.5" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Neutrophils_2, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034563 Uncertain Approved Vesicles,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 24: Neutrophils - Innate immunity signal integration" 26 "Vesicles, Cytosol" "HPA034563: " "unprognostic (1.14e-1)" "unprognostic (1.73e-1)" "unprognostic (6.78e-2)" "potential prognostic unfavorable (9.32e-4)" "unprognostic (3.26e-2)" "unprognostic (1.29e-2)" "unprognostic (1.52e-1)" "unprognostic (8.72e-3)" "unprognostic (8.58e-2)" "unprognostic (3.32e-3)" "potential prognostic favorable (1.45e-7)" "unprognostic (9.54e-3)" "unprognostic (2.59e-3)" "unprognostic (8.40e-2)" "unprognostic (1.02e-2)" "unprognostic (1.47e-1)" "unprognostic (1.09e-1)" "unprognostic (1.46e-1)" "unprognostic (1.64e-1)" "unprognostic (1.16e-1)" "unprognostic (5.69e-2)" "unprognostic (6.41e-2)" "unprognostic (1.31e-3)" "unprognostic (7.55e-2)" "unprognostic (1.30e-1)" "unprognostic (1.62e-2)" "unprognostic (2.25e-1)" "unprognostic (1.29e-1)" "unprognostic (1.70e-1)" "unprognostic (4.93e-3)" "unprognostic (1.04e-1)" SLC12A7 "DKFZP434F076, KCC4" ENSG00000113504 "Solute carrier family 12 member 7" Q9Y666 5 1050384-1112063 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 71.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 27.0;Choroid plexus epithelial cells: 17.4;Distal convoluted tubule cells: 19.4;Ependymal cells: 43.8;Loop of henle epithelial cells: 19.4;Microglia: 26.9;Papillary tip epithelial cells: 24.3;Pericytes: 26.7;Podocytes: 17.6;Proximal tubule cells: 74.6;Renal collecting duct intercalated cells: 31.7;Renal collecting duct principal cells: 43.8;Renal connecting tubule cells: 21.7" "Cell type enriched" "Detected in many" 11 "pericyte: 581.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Kidney - Macrophages, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041652 Approved Uncertain Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 70: Non-specific - Protein processing" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 22: Non-specific - Basic cellular functions" 24 Cytosol "HPA041652: " "unprognostic (1.69e-1)" "unprognostic (1.68e-2)" "unprognostic (5.43e-2)" "unprognostic (2.66e-2)" "unprognostic (2.03e-1)" "unprognostic (3.16e-1)" "unprognostic (1.04e-2)" "unprognostic (1.07e-3)" "unprognostic (8.11e-2)" "unprognostic (5.32e-2)" "validated prognostic favorable (2.48e-7)" "validated prognostic favorable (6.76e-4)" "unprognostic (4.16e-1)" "potential prognostic unfavorable (8.96e-6)" "unprognostic (1.31e-1)" "unprognostic (2.31e-1)" "unprognostic (2.58e-1)" "unprognostic (1.19e-2)" "unprognostic (1.24e-1)" "unprognostic (1.44e-2)" "unprognostic (2.29e-2)" "unprognostic (4.90e-2)" "unprognostic (4.57e-3)" "unprognostic (1.38e-1)" "unprognostic (2.86e-1)" "unprognostic (5.10e-2)" "unprognostic (1.46e-2)" "unprognostic (7.49e-3)" "unprognostic (6.50e-2)" "unprognostic (2.24e-2)" "unprognostic (6.42e-2)" SLC12A8 CCC9 ENSG00000221955 "Solute carrier family 12 member 8" A0AV02 3 125082636-125212864 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 21.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 74.8;Choroid plexus epithelial cells: 154.6;Goblet cells: 156.6;Lacrimal acinar cells: 76.1;Salivary acinar cells: 83.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Stomach - Mitotic cells (Stomach), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA031123 Uncertain Approved Nucleoplasm NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 60: Stomach - Digestion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 70: Intestinal goblet cells - Mucin production" 1 Nucleoplasm "HPA031123: " "unprognostic (8.76e-2)" "unprognostic (5.88e-2)" "unprognostic (8.50e-2)" "unprognostic (3.64e-2)" "unprognostic (4.08e-2)" "unprognostic (9.67e-2)" "potential prognostic unfavorable (4.43e-4)" "unprognostic (8.62e-2)" "unprognostic (3.70e-1)" "unprognostic (2.48e-2)" "potential prognostic unfavorable (5.75e-8)" "unprognostic (5.97e-3)" "unprognostic (1.70e-2)" "unprognostic (1.49e-1)" "unprognostic (5.17e-2)" "unprognostic (5.87e-3)" "unprognostic (3.74e-3)" "unprognostic (1.37e-1)" "unprognostic (1.48e-1)" "unprognostic (8.93e-2)" "unprognostic (1.50e-2)" "unprognostic (1.39e-1)" "unprognostic (8.98e-2)" "unprognostic (2.38e-2)" "unprognostic (6.69e-2)" "unprognostic (1.42e-2)" "unprognostic (4.58e-2)" "unprognostic (4.32e-1)" "unprognostic (2.54e-2)" "unprognostic (3.04e-2)" SLC12A9 CIP1 ENSG00000146828 "Solute carrier family 12 member 9" Q9BXP2 7 100826820-100867010 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 123.7;Migrating cytotrophoblasts: 75.9;Neutrophils: 94.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067536 Approved NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 39: Non-specific - Transcription" "Cluster 24: Neutrophils - Innate immunity signal integration" 2 "HPA067536: " "unprognostic (1.05e-1)" "unprognostic (3.10e-2)" "unprognostic (2.78e-1)" "unprognostic (6.30e-2)" "unprognostic (3.55e-1)" "unprognostic (1.74e-1)" "unprognostic (8.92e-2)" "unprognostic (1.39e-1)" "unprognostic (3.40e-2)" "unprognostic (3.28e-2)" "potential prognostic favorable (2.67e-4)" "unprognostic (3.30e-2)" "potential prognostic favorable (7.46e-4)" "unprognostic (5.63e-2)" "unprognostic (2.47e-2)" "unprognostic (2.89e-2)" "unprognostic (2.54e-1)" "unprognostic (4.41e-2)" "unprognostic (1.77e-1)" "unprognostic (3.55e-3)" "unprognostic (2.07e-1)" "unprognostic (2.14e-1)" "unprognostic (1.32e-1)" "unprognostic (1.63e-1)" "unprognostic (6.09e-2)" "unprognostic (8.66e-2)" "unprognostic (1.16e-1)" "unprognostic (3.59e-2)" "unprognostic (1.19e-1)" "unprognostic (1.25e-2)" "unprognostic (1.03e-1)" SLC13A1 "NAS1, NaSi-1" ENSG00000081800 "Solute carrier family 13 member 1" Q9BZW2 7 123113531-123199972 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Sulfate transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "kidney: 76.4" "Group enriched" "Detected in some" 13 "Enterocytes: 213.4;Proximal tubule cells: 767.4" "Cell type enhanced" "Detected in single" "upper rhombic lip: 1.2" "Group enriched" "Detected in some" 186 "Kidney Renal Clear Cell Carcinoma (TCGA): 11.6;Kidney Renal Papillary Cell Carcinoma (TCGA): 25.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA053615, HPA062714" Enhanced NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 88: Proximal tubular cells - Transmembrane transport" "HPA053615: , HPA062714: " "potential prognostic favorable (2.67e-7)" "unprognostic (1.80e-3)" "unprognostic (1.83e-2)" SLC13A2 NaDC-1 ENSG00000007216 "Solute carrier family 13 member 2" Q13183 17 28473293-28497781 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "intestine: 121.8;kidney: 40.2;salivary gland: 45.4" "Group enriched" "Detected in some" 4 "Enterocytes: 345.5;Lacrimal acinar cells: 110.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 9 "choroid plexus: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Breast glandular cells (progenitors), Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Ductal cells, Prostate - Urothelial cells, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA014963 Enhanced NA NA "Cluster 77: Intestine - Digestion" "Cluster 36: Choroid plexus - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 1: Enterocytes - Absorption and Digestion" 3 "HPA014963: " "unprognostic (4.19e-1)" "unprognostic (1.57e-1)" "unprognostic (1.34e-1)" "unprognostic (7.33e-2)" "unprognostic (1.94e-1)" "unprognostic (1.94e-3)" "unprognostic (1.02e-2)" "unprognostic (1.93e-1)" "unprognostic (3.21e-1)" "unprognostic (2.00e-1)" "unprognostic (8.16e-3)" "unprognostic (4.19e-1)" "unprognostic (7.64e-2)" "unprognostic (6.83e-2)" "unprognostic (2.61e-2)" "unprognostic (1.13e-1)" "unprognostic (1.07e-1)" "unprognostic (1.02e-1)" SLC13A3 "NADC3, SDCT2" ENSG00000158296 "Solute carrier family 13 member 3" Q8WWT9 20 46557823-46684467 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Lipid transport, Sodium transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "kidney: 379.8" "Cell type enriched" "Detected in many" 4 "Proximal tubule cells: 1346.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Kidney - Proximal tubular cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Stomach - Chief cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014333, HPA014353, HPA014736" Enhanced Supported "Plasma membrane" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 88: Proximal tubular cells - Transmembrane transport" 9 "Plasma membrane" "HPA014333: , HPA014353: , HPA014736: " "unprognostic (3.25e-1)" "unprognostic (2.33e-3)" "unprognostic (2.38e-1)" "unprognostic (6.64e-2)" "unprognostic (1.11e-1)" "unprognostic (8.38e-2)" "unprognostic (3.28e-1)" "unprognostic (3.43e-2)" "unprognostic (4.18e-2)" "unprognostic (8.47e-2)" "unprognostic (2.74e-2)" "unprognostic (3.42e-2)" "unprognostic (7.13e-2)" "unprognostic (1.64e-1)" "unprognostic (6.59e-3)" "unprognostic (1.99e-2)" "unprognostic (2.31e-1)" "unprognostic (8.68e-2)" "unprognostic (1.96e-1)" "unprognostic (9.82e-2)" "unprognostic (3.71e-2)" "unprognostic (1.09e-2)" "unprognostic (2.20e-1)" "unprognostic (3.85e-2)" "unprognostic (9.89e-2)" "unprognostic (3.69e-2)" "potential prognostic unfavorable (5.51e-4)" "unprognostic (5.89e-2)" "unprognostic (2.31e-1)" "unprognostic (1.37e-1)" "unprognostic (3.12e-1)" SLC13A4 "SUT-1, SUT1" ENSG00000164707 "Solute carrier family 13 member 4" Q9UKG4 7 135681231-135729258 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 27 "choroid plexus: 1460.7" "Group enriched" "Detected in many" 4 "Choroid plexus epithelial cells: 1851.2;Syncytiotrophoblasts: 1148.6" "Cell type enriched" "Detected in all" 16 "choroid plexus epithelial cell: 1560.9" "Cancer enriched" "Detected in single" 5 "Testicular Germ Cell Tumor (TCGA): 4.6" "Region enriched" "Detected in all" 20 "choroid plexus: 1925.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 1.9;testis cancer: 3.1" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048582 Enhanced NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 22 "HPA048582: " "unprognostic (2.10e-1)" "unprognostic (1.13e-1)" SLC13A5 "INDY, NACT" ENSG00000141485 "Solute carrier family 13 member 5" Q86YT5 17 6684719-6713377 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Amelogenesis imperfecta, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "liver: 393.9" "Cell type enhanced" "Detected in some" "Astrocytes: 42.5;Bergmann glia: 29.1;Hepatocytes: 440.0;Salivary acinar cells: 242.2;Salivary myoepithelial cells: 97.6" "Group enriched" "Detected in some" 4 "astrocyte: 36.0;Bergmann glia: 28.8" "Cancer enriched" "Detected in many" 13 "Liver Hepatocellular Carcinoma (TCGA): 91.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "Bile duct cancer: 2.9;liver cancer: 6.5" "Pituitary gland - Undifferentiated cells (Pituitary gland)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044343 Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 18: Liver cancer - Metabolism" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 17 "Nucleoplasm, Plasma membrane" "HPA044343: " "unprognostic (6.76e-2)" "unprognostic (2.26e-1)" "unprognostic (1.95e-1)" "unprognostic (1.18e-1)" "unprognostic (1.09e-1)" "unprognostic (1.59e-2)" "potential prognostic favorable (7.33e-4)" "unprognostic (1.99e-1)" "unprognostic (1.21e-2)" "unprognostic (3.78e-1)" "unprognostic (6.33e-2)" "unprognostic (2.71e-3)" "unprognostic (5.15e-2)" "unprognostic (6.06e-2)" "unprognostic (1.43e-1)" SLC14A1 "HsT1341, JK, RACH1, RACH2" ENSG00000141469 "Solute carrier family 14 member 1 (Kidd blood group)" Q13336 18 45687025-45752520 "Blood group antigen proteins, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 46.0;brain: 51.7;kidney: 46.4;prostate: 73.4;urinary bladder: 84.8" "Cell type enhanced" "Detected in many" "Astrocytes: 477.7;Basal prostatic cells: 150.3;Ependymal cells: 100.6;Lacrimal acinar cells: 106.0;Medullary thymic epithelial cells: 285.6;Megakaryocyte-Erythroid progenitors: 128.9;Papillary tip epithelial cells: 168.2;Prostatic hillock cells: 324.8;Salivary ionocytes: 83.6;Urothelial cells: 313.3" "Cell type enriched" "Detected in many" 9 "astrocyte: 756.9" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 36.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 4.1" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Brain cancer: 35.3;thyroid cancer: 34.9" "Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059570, HPA077233" Approved Supported "Plasma membrane" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 44: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 28: Astrocytes - Homeostasis & neuron support" 22 "Plasma membrane" "HPA059570: , HPA077233: " "unprognostic (2.48e-2)" "unprognostic (8.13e-2)" "unprognostic (1.85e-1)" "unprognostic (6.19e-2)" "unprognostic (5.15e-2)" "unprognostic (3.98e-2)" "unprognostic (8.36e-2)" "unprognostic (3.44e-1)" "unprognostic (8.71e-3)" "potential prognostic favorable (2.98e-5)" "unprognostic (3.99e-3)" "unprognostic (7.52e-2)" "potential prognostic favorable (1.08e-5)" "unprognostic (1.96e-2)" "unprognostic (1.50e-2)" "unprognostic (2.56e-2)" "unprognostic (4.85e-2)" "unprognostic (2.80e-1)" "unprognostic (3.45e-1)" "unprognostic (1.85e-1)" "unprognostic (2.30e-1)" "unprognostic (1.13e-1)" "unprognostic (1.47e-1)" "unprognostic (1.69e-1)" "unprognostic (1.77e-1)" SLC14A2 "HUT2, UT2" ENSG00000132874 "Solute carrier family 14 member 2" Q15849 18 45212995-45683688 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 4.3" "Cell type enriched" "Detected in many" 7 "Renal collecting duct principal cells: 4867.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 1.5" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.5" "Cancer enhanced" "Detected in some" "Uterine cancer: 3.6" "Region enhanced" "Detected in many" "basal ganglia: 16.9" "Low region specificity" "Detected in many" HPA050069 Supported NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 9: Non-specific - Receptor signaling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 11 "HPA050069: " "unprognostic (1.35e-2)" "unprognostic (6.82e-2)" "unprognostic (3.12e-2)" "unprognostic (2.93e-3)" "unprognostic (2.70e-2)" "unprognostic (9.97e-2)" "unprognostic (8.81e-2)" "unprognostic (5.83e-2)" "unprognostic (5.55e-3)" SLC15A1 "HPECT1, HPEPT1, PEPT1" ENSG00000088386 "Solute carrier family 15 member 1" P46059 13 98683801-98752672 "Metabolic proteins, Predicted membrane proteins, Transporters" "Peptide transport, Protein transport, Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "intestine: 191.1" "Group enriched" "Detected in many" 5 "Endometrial glandular cells: 248.0;Enterocytes: 816.2" "Group enriched" "Detected in some" 9 "choroid plexus epithelial cell: 8.6;thalamic excitatory: 11.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 7.4;pancreatic cancer: 11.1" "Colon - Colon enterocytes, Liver - Hepatocytes, Prostate - Prostate glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA002827 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 51: Secretory epithelial cells - Mixed function" 1 "Nucleoplasm, Cytosol" "HPA002827: " "unprognostic (1.99e-2)" "unprognostic (4.39e-2)" "unprognostic (6.17e-2)" "unprognostic (4.38e-2)" "unprognostic (2.56e-2)" "unprognostic (1.61e-2)" "unprognostic (7.07e-2)" "unprognostic (7.28e-2)" "unprognostic (8.69e-2)" "unprognostic (5.79e-3)" "unprognostic (2.85e-1)" "unprognostic (1.43e-1)" "unprognostic (5.56e-3)" "unprognostic (9.51e-2)" "unprognostic (3.31e-1)" "unprognostic (1.98e-1)" "unprognostic (2.79e-1)" "unprognostic (1.03e-2)" "potential prognostic unfavorable (5.98e-4)" "unprognostic (1.42e-3)" "unprognostic (3.11e-1)" "unprognostic (7.05e-2)" "unprognostic (1.69e-2)" "unprognostic (3.57e-1)" "unprognostic (1.61e-1)" "unprognostic (2.46e-2)" SLC15A2 PEPT2 ENSG00000163406 "Solute carrier family 15 member 2" Q16348 3 121894401-121944188 "Metabolic proteins, Predicted membrane proteins, Transporters" "Immunity, Innate immunity, Peptide transport, Protein transport, Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 47.8;epididymis: 37.0;prostate: 37.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 132.3;Astrocytes: 206.0;Bergmann glia: 95.4;Conjunctival goblet cells: 100.0;Ependymal cells: 124.3;Microglia: 159.9;Müller glia: 100.0;Neutrophil progenitors: 114.6;Prostatic glandular cells: 132.7;Respiratory secretory cells: 163.0;Salivary duct cells: 157.7" "Cell type enhanced" "Detected in all" "astrocyte: 211.2;central nervous system macrophage: 190.6;ependymal cell: 142.1" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 23.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Minor Salivary Gland - Minor salivary gland ductal cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 32: Basophils - Transcription" "Cluster 22: Epididymis - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 21 "unprognostic (5.13e-2)" "unprognostic (3.67e-2)" "unprognostic (8.72e-2)" "unprognostic (1.50e-2)" "unprognostic (5.58e-2)" "unprognostic (2.11e-3)" "unprognostic (5.83e-1)" "unprognostic (5.80e-2)" "unprognostic (6.59e-2)" "unprognostic (2.24e-1)" "unprognostic (7.69e-2)" "potential prognostic favorable (2.74e-4)" "unprognostic (3.13e-1)" "unprognostic (1.71e-1)" "unprognostic (8.98e-2)" "unprognostic (2.40e-1)" "unprognostic (1.78e-2)" "unprognostic (4.42e-2)" "potential prognostic unfavorable (1.08e-4)" "unprognostic (1.08e-1)" "unprognostic (3.14e-2)" "unprognostic (1.92e-1)" "unprognostic (9.72e-2)" "unprognostic (2.49e-1)" "unprognostic (1.37e-1)" SLC15A3 "hPTR3, PHT2" ENSG00000110446 "Solute carrier family 15 member 3" Q8IY34 11 60937060-60952653 "Metabolic proteins, Predicted membrane proteins, Transporters" "Immunity, Innate immunity, Peptide transport, Protein transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "cDC: 48.5;Hofbauer cells: 116.6;Kupffer cells: 88.1;Macrophages: 87.2;monocytes: 125.4;Müller glia: 204.6;Neutrophils: 238.4;Schwann cells: 141.6" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 47.0;endothelial cell: 19.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 9.0;intermediate monocyte: 12.8;memory B-cell: 4.9;myeloid DC: 6.5;neutrophil: 13.4;non-classical monocyte: 6.4;plasmacytoid DC: 10.7" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "lymphoma: 18.5" "Adrenal gland - Macrophages, Colon - Enteric glia cells, Lung - Macrophages, Minor Salivary Gland - Macrophages, Spleen - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA047880, HPA057642" Approved Supported Vesicles NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 41 Vesicles "HPA047880: , HPA057642: " "unprognostic (7.01e-2)" "unprognostic (1.51e-1)" "unprognostic (3.24e-1)" "unprognostic (1.61e-2)" "unprognostic (1.54e-1)" "unprognostic (1.36e-1)" "unprognostic (2.71e-2)" "unprognostic (9.57e-2)" "unprognostic (4.83e-2)" "unprognostic (2.49e-1)" "unprognostic (2.98e-2)" "unprognostic (3.69e-1)" "unprognostic (4.58e-3)" "unprognostic (2.54e-2)" "unprognostic (8.50e-3)" "unprognostic (4.45e-1)" "unprognostic (2.25e-2)" "unprognostic (2.50e-1)" "unprognostic (1.61e-1)" "unprognostic (1.33e-1)" "unprognostic (8.31e-3)" "unprognostic (1.57e-1)" "unprognostic (7.02e-2)" "unprognostic (8.40e-2)" "unprognostic (2.20e-1)" "unprognostic (6.75e-2)" "unprognostic (2.20e-1)" "unprognostic (2.02e-1)" "unprognostic (1.48e-2)" "unprognostic (1.04e-1)" "unprognostic (1.03e-1)" SLC15A4 "PHT1, PTR4" ENSG00000139370 "Solute carrier family 15 member 4" Q8N697 12 128793194-128823958 "Metabolic proteins, Predicted membrane proteins, Transporters" "Immunity, Innate immunity, Peptide transport, Protein transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 259.8;Late primary spermatocytes: 148.5;Late spermatids: 186.1;Müller glia: 261.5;Neutrophils: 390.8;pDCs: 539.7" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 213.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 31.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016713 Approved NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 15: Kidney cancer - Membrane components" "Cluster 24: Neutrophils - Innate immunity signal integration" 20 "HPA016713: " "unprognostic (1.00e-2)" "unprognostic (9.46e-2)" "unprognostic (3.20e-1)" "unprognostic (8.55e-3)" "unprognostic (1.65e-1)" "unprognostic (1.60e-1)" "unprognostic (3.20e-1)" "unprognostic (2.34e-2)" "unprognostic (1.85e-2)" "unprognostic (1.15e-1)" "potential prognostic favorable (1.86e-6)" "unprognostic (8.67e-2)" "unprognostic (3.64e-3)" "unprognostic (1.14e-3)" "unprognostic (1.40e-1)" "unprognostic (9.36e-3)" "unprognostic (2.19e-2)" "unprognostic (2.71e-3)" "unprognostic (1.16e-2)" "unprognostic (3.40e-2)" "unprognostic (1.10e-1)" "unprognostic (2.50e-2)" "unprognostic (4.31e-3)" "unprognostic (3.75e-1)" "unprognostic (2.66e-1)" "unprognostic (2.15e-2)" "unprognostic (5.22e-1)" "unprognostic (1.51e-1)" "unprognostic (2.57e-1)" "unprognostic (2.07e-1)" "unprognostic (1.38e-1)" SLC15A5 ENSG00000188991 "Solute carrier family 15 member 5" A6NIM6 12 16188485-16277685 "Predicted membrane proteins, Transporters" "Peptide transport, Protein transport, Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Adipocytes: 57.9;Astrocytes: 7.2;Bergmann glia: 10.7;Cardiomyocytes: 16.6;Differentiating spermatogonia: 5.8;Early spermatids: 5.5;Late primary spermatocytes: 6.1;Rod photoreceptor cells: 7.3;Undifferentiated spermatogonia: 13.5" "Group enriched" "Detected in some" 4 "astrocyte: 12.3;Bergmann glia: 16.5;deep-layer corticothalamic and 6b: 45.0;deep-layer near-projecting: 41.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA041638 Uncertain NA NA "Cluster 51: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 89: Adipocytes - Lipid metabolism" 1 "HPA041638: " SLC16A1 "MCT, MCT1" ENSG00000155380 "Solute carrier family 16 member 1" P53985 1 112911847-112957593 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 54.6;Early spermatids: 46.3;Ependymal cells: 50.0;Late spermatids: 57.6;Müller glia: 56.0;Oligodendrocytes: 38.1;Proximal tubule cells: 30.4;Retinal pigment epithelial cells: 38.4;Rod photoreceptor cells: 27.5" "Cell type enhanced" "Detected in all" "endothelial cell: 178.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 6.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003324, CAB017489, HPA071055, CAB079035" Enhanced Supported Enhanced "Plasma membrane,Cell Junctions" NA NA 15000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 47: Endothelial cells - Vasculature" "Cluster 34: Testis cancer - Unknown function" "Cluster 104: Brain endothelial cells - Blood brain barrier" 27 "Plasma membrane, Cell Junctions" "CAB017489: , CAB079035: , HPA003324: , HPA071055: " "unprognostic (1.30e-2)" "unprognostic (1.01e-1)" "unprognostic (7.38e-2)" "unprognostic (5.28e-3)" "unprognostic (1.44e-1)" "unprognostic (3.94e-1)" "unprognostic (4.66e-2)" "unprognostic (3.48e-2)" "unprognostic (1.59e-2)" "potential prognostic unfavorable (5.73e-6)" "unprognostic (8.11e-3)" "unprognostic (1.60e-1)" "unprognostic (4.02e-2)" "unprognostic (6.52e-3)" "unprognostic (2.50e-3)" "potential prognostic unfavorable (2.39e-6)" "unprognostic (1.76e-2)" "unprognostic (7.00e-2)" "unprognostic (1.40e-1)" "unprognostic (2.87e-2)" "unprognostic (2.24e-1)" "potential prognostic unfavorable (4.85e-4)" "unprognostic (2.50e-1)" "unprognostic (1.53e-2)" "unprognostic (2.59e-2)" "unprognostic (2.35e-1)" "unprognostic (8.65e-2)" "unprognostic (1.06e-1)" "unprognostic (3.32e-1)" "unprognostic (1.26e-2)" "unprognostic (5.01e-2)" SLC16A10 "MCT10, TAT1" ENSG00000112394 "Solute carrier family 16 member 10" Q8TF71 6 111087503-111231194 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 24.8;pancreas: 28.0;skeletal muscle: 33.7" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 986.0;Macrophages: 529.7;Melanocytes: 400.0;monocytes: 548.4;Myonuclei: 1010.3;Pancreatic acinar cells: 217.6;Podocytes: 374.8" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 788.2" "Group enriched" "Detected in all" 4 "Kidney Chromophobe (TCGA): 6.0;Testicular Germ Cell Tumor (TCGA): 24.0" "Region enhanced" "Detected in all" "choroid plexus: 86.5" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 1.7;T-reg: 1.6" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Kidney - Proximal tubular cells, Skin - Keratinocyte (other), Spleen - Macrophages, Stomach - Chief cells, Testis - Spermatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA016860 Approved Supported "Vesicles,Cell Junctions" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 4 "Vesicles, Cell Junctions" "HPA016860: " "unprognostic (5.80e-2)" "unprognostic (1.40e-1)" "unprognostic (2.87e-1)" "unprognostic (3.16e-1)" "unprognostic (1.75e-1)" "unprognostic (2.61e-1)" "unprognostic (6.11e-2)" "unprognostic (6.01e-2)" "unprognostic (2.59e-1)" "unprognostic (5.95e-3)" "unprognostic (1.33e-1)" "unprognostic (8.11e-2)" "unprognostic (1.88e-2)" "unprognostic (1.15e-1)" "unprognostic (1.01e-1)" "unprognostic (3.17e-2)" "unprognostic (2.75e-2)" "unprognostic (2.47e-1)" "unprognostic (3.34e-2)" "unprognostic (1.66e-1)" "unprognostic (7.75e-2)" "unprognostic (6.29e-2)" "unprognostic (3.46e-2)" "unprognostic (1.67e-1)" "unprognostic (3.04e-1)" "unprognostic (2.98e-1)" "unprognostic (3.93e-2)" "unprognostic (6.42e-2)" "unprognostic (1.63e-1)" "unprognostic (6.55e-2)" "unprognostic (1.26e-1)" SLC16A11 "FLJ90193, MCT11" ENSG00000174326 "Solute carrier family 16 member 11" 17 7041621-7044092 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "choroid plexus: 11.8" "Cell type enhanced" "Detected in many" "Epididymal clear cells: 53.1;Epididymal efferent duct absorptive cells: 22.1;Epididymal principal cells: 22.1;Fallopian tube ciliated cells: 92.4;Müller glia: 27.7;Respiratory secretory cells: 21.0;Salivary ionocytes: 17.7;Tuft cells: 23.1" "Cell type enhanced" "Detected in many" "ependymal cell: 10.8" "Group enriched" "Detected in many" 10 "Kidney Chromophobe (TCGA): 41.7;Liver Hepatocellular Carcinoma (TCGA): 17.5;Thyroid Carcinoma (TCGA): 10.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 8 "B-cells: 1.0;T-cells: 1.5" "Cancer enhanced" "Detected in single" "Bone cancer: 1.3" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 8: Immune cells - Immune response" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 1 "unprognostic (2.09e-2)" "potential prognostic favorable (1.68e-5)" "unprognostic (8.92e-2)" "potential prognostic unfavorable (3.39e-4)" "unprognostic (1.76e-2)" "potential prognostic favorable (7.38e-6)" "unprognostic (1.96e-1)" "potential prognostic favorable (6.16e-4)" "unprognostic (7.05e-3)" "potential prognostic favorable (7.89e-4)" "unprognostic (1.33e-1)" "unprognostic (2.14e-1)" "unprognostic (2.06e-1)" "potential prognostic favorable (5.86e-6)" "unprognostic (1.05e-1)" "unprognostic (2.24e-2)" "unprognostic (1.94e-1)" "unprognostic (1.40e-1)" SLC16A12 MCT12 ENSG00000152779 "Solute carrier family 16 member 12" Q6ZSM3 10 89430299-89556641 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cataract, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 56.1;epididymis: 48.8;kidney: 79.4" "Group enriched" "Detected in many" 4 "Choroid plexus epithelial cells: 588.7;Loop of henle epithelial cells: 504.3;Proximal tubule cells: 1235.4;Retinal pigment epithelial cells: 417.8" "Group enriched" "Detected in many" 5 "choroid plexus epithelial cell: 500.0;fibroblast: 261.7" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 37.8;Kidney Renal Papillary Cell Carcinoma (TCGA): 25.0" "Region enriched" "Detected in all" 29 "choroid plexus: 194.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney cancer: 9.0;liver cancer: 5.5" "Pituitary gland - Corticotropes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 88: Proximal tubular cells - Transmembrane transport" 3 "unprognostic (1.39e-1)" "unprognostic (1.70e-2)" "unprognostic (3.45e-2)" "potential prognostic favorable (0.00e+0)" "unprognostic (1.25e-2)" "unprognostic (5.03e-2)" "unprognostic (4.77e-1)" "unprognostic (3.15e-1)" "unprognostic (2.37e-2)" "unprognostic (4.44e-1)" "unprognostic (6.23e-2)" "unprognostic (9.01e-3)" "unprognostic (2.41e-1)" "unprognostic (2.51e-3)" SLC16A13 MCT13 ENSG00000174327 "Solute carrier family 16 member 13" Q7RTY0 17 7036015-7040117 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Symport, Transport" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 33.8" "Cell type enhanced" "Detected in many" "Paneth cells: 30.9;Proximal tubule cells: 18.8;Tuft cells: 23.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065245 Supported "Golgi apparatus,Cytosol" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 25: Non-specific - Transcription" "Cluster 42: Non-specific - Unknown function" "Cluster 65: Non-specific - Cell growth & division" 16 "Golgi apparatus" Cytosol "HPA065245: " "unprognostic (7.21e-2)" "unprognostic (2.30e-1)" "unprognostic (1.17e-1)" "unprognostic (2.07e-2)" "unprognostic (4.45e-2)" "unprognostic (2.00e-1)" "unprognostic (4.21e-2)" "unprognostic (1.74e-2)" "unprognostic (1.09e-1)" "unprognostic (5.88e-3)" "potential prognostic favorable (4.13e-5)" "unprognostic (2.23e-2)" "unprognostic (2.00e-1)" "unprognostic (1.27e-1)" "unprognostic (2.45e-2)" "unprognostic (7.85e-3)" "unprognostic (2.15e-1)" "unprognostic (7.10e-2)" "unprognostic (2.01e-2)" "unprognostic (1.04e-1)" "unprognostic (4.91e-1)" "unprognostic (2.92e-3)" "unprognostic (5.12e-3)" "unprognostic (2.61e-1)" "unprognostic (2.14e-1)" "unprognostic (3.88e-3)" "unprognostic (7.13e-2)" "unprognostic (8.49e-2)" "unprognostic (1.70e-1)" "unprognostic (1.57e-2)" "unprognostic (1.47e-1)" SLC16A14 "FLJ30794, MCT14" ENSG00000163053 "Solute carrier family 16 member 14" Q7RTX9 2 230034982-230068993 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 17.5" "Cell type enriched" "Detected in many" 13 "Retinal pigment epithelial cells: 852.6" "Cell type enhanced" "Detected in all" "endothelial cell: 192.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 24 "eosinophil: 11.3" "Lineage enriched" "Detected in single" 24 "granulocytes: 11.3" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 21.7" "Adipose subcutaneous - Endothelial cells, Kidney - Endothelial cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040518 Uncertain Approved "Endoplasmic reticulum" No No "Cluster 22: Eosinophils - Transcription" "Cluster 65: Brain - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 7: Liver cancer - Metabolism" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" "Endoplasmic reticulum" "HPA040518: " "unprognostic (2.46e-2)" "unprognostic (1.46e-1)" "unprognostic (2.65e-1)" "unprognostic (1.71e-1)" "unprognostic (6.41e-2)" "unprognostic (1.39e-1)" "unprognostic (1.96e-3)" "unprognostic (9.13e-3)" "unprognostic (3.75e-1)" "unprognostic (2.76e-3)" "unprognostic (7.07e-3)" "unprognostic (9.94e-3)" "unprognostic (2.30e-2)" "unprognostic (5.82e-2)" "unprognostic (2.99e-2)" "unprognostic (3.83e-2)" "unprognostic (5.10e-2)" "unprognostic (2.74e-3)" "unprognostic (3.65e-2)" "unprognostic (1.29e-1)" "unprognostic (3.30e-2)" "unprognostic (2.45e-2)" "unprognostic (1.12e-1)" "unprognostic (1.14e-1)" "unprognostic (1.72e-1)" "unprognostic (6.83e-2)" "unprognostic (1.26e-1)" "unprognostic (1.16e-2)" "unprognostic (2.50e-2)" SLC16A2 "AHDS, DXS128, DXS128E, MCT7, MCT8, MRX22, XPCT" ENSG00000147100 "Solute carrier family 16 member 2" P36021 X 74421493-74533917 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 38.1" "Cell type enriched" "Detected in many" 4 "Pituitary stem cells: 500.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 66.9" "Adrenal gland - Adrenal cortex cells, Heart muscle - Fibroblasts, Liver - Hepatocytes, Pituitary gland - Undifferentiated cells (Pituitary gland), Prostate - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072719 Approved "Plasma membrane" NA NA "Cluster 76: Non-specific - Metabolism" "Cluster 29: Forebrain - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 5 "Plasma membrane" "HPA072719: " "unprognostic (2.33e-2)" "potential prognostic unfavorable (2.75e-4)" "unprognostic (9.31e-2)" "unprognostic (2.12e-2)" "unprognostic (9.04e-2)" "unprognostic (1.83e-1)" "unprognostic (1.79e-1)" "unprognostic (3.65e-2)" "unprognostic (2.10e-2)" "unprognostic (2.78e-2)" "potential prognostic favorable (4.27e-5)" "unprognostic (1.41e-2)" "unprognostic (5.71e-3)" "unprognostic (5.48e-2)" "unprognostic (3.64e-2)" "unprognostic (1.20e-1)" "unprognostic (6.54e-3)" "unprognostic (1.12e-1)" "unprognostic (2.28e-2)" "unprognostic (5.07e-2)" "unprognostic (5.54e-2)" "unprognostic (6.77e-2)" "unprognostic (5.98e-3)" "unprognostic (2.68e-1)" "unprognostic (6.37e-2)" "unprognostic (1.08e-1)" "unprognostic (1.66e-1)" "unprognostic (8.42e-2)" "unprognostic (1.09e-1)" "unprognostic (5.17e-3)" "unprognostic (1.73e-1)" SLC16A3 "MCT3, MCT4" ENSG00000141526 "Solute carrier family 16 member 3" O15427 17 82217934-82261129 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 134.4" "Cell type enhanced" "Detected in many" "Epicardial cells: 379.8;Esophageal apical cells: 585.4;Extravillous trophoblasts: 2420.5;Migrating cytotrophoblasts: 355.8;Neutrophils: 849.6;Retinal pigment epithelial cells: 660.8;Syncytiotrophoblasts: 884.7" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 45.2;leukocyte: 34.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 110.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Macrophages, Lung - Neutrophils_2, Spleen - Neutrophils_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB017490, HPA021451" Approved Supported "Nuclear membrane,Plasma membrane" NA NA 28000 "Cluster 21: Neutrophils - Unknown function" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 10 "Plasma membrane" "Nuclear membrane" "CAB017490: , HPA021451: " "unprognostic (1.07e-2)" "unprognostic (1.95e-1)" "unprognostic (2.01e-1)" "potential prognostic unfavorable (4.92e-4)" "unprognostic (6.84e-2)" "unprognostic (2.56e-1)" "unprognostic (1.31e-3)" "unprognostic (1.76e-3)" "unprognostic (1.40e-2)" "unprognostic (4.71e-1)" "unprognostic (1.74e-2)" "unprognostic (1.59e-2)" "unprognostic (2.33e-1)" "potential prognostic unfavorable (1.05e-7)" "unprognostic (9.31e-2)" "validated prognostic unfavorable (9.21e-7)" "validated prognostic unfavorable (7.01e-4)" "unprognostic (1.74e-2)" "unprognostic (1.74e-1)" "unprognostic (1.35e-2)" "unprognostic (1.53e-1)" "unprognostic (8.14e-3)" "unprognostic (1.27e-2)" "unprognostic (1.25e-1)" "unprognostic (4.37e-2)" "unprognostic (2.43e-1)" "unprognostic (6.79e-2)" "unprognostic (1.77e-1)" "unprognostic (2.99e-2)" "unprognostic (1.97e-2)" "unprognostic (7.34e-2)" SLC16A4 "MCT4, MCT5" ENSG00000168679 "Solute carrier family 16 member 4" O15374 1 110362851-110391082 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "kidney: 115.8" "Cell type enhanced" "Detected in many" "Adipocytes: 110.6;Cardiomyocytes: 160.5;Myonuclei: 110.1;Proximal tubule cells: 125.7;Renal collecting duct principal cells: 96.8;Renal connecting tubule cells: 79.6" "Cell type enhanced" "Detected in all" "endothelial cell: 76.0" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 62.8;Kidney Renal Papillary Cell Carcinoma (TCGA): 63.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "memory B-cell: 1.5" "Lineage enriched" "Detected in single" 4 "B-cells: 1.5" "Cancer enhanced" "Detected in all" "Kidney cancer: 31.1" "Adrenal gland - Fibroblasts, Colon - Enteric glia cells, Heart muscle - Fibroblasts, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046986, HPA060163" Approved Approved "Microtubules,Cytokinetic bridge,Cytosol" Yes NA "Cluster 18: Non-specific - Translation" "Cluster 72: Kidney - Transmembrane transport" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 88: Proximal tubular cells - Transmembrane transport" 1 "Microtubules, Cytosol" "Cytokinetic bridge" "HPA046986: , HPA060163: " "unprognostic (2.13e-1)" "unprognostic (1.36e-1)" "unprognostic (4.83e-2)" "unprognostic (9.52e-2)" "unprognostic (2.10e-1)" "unprognostic (2.06e-1)" "unprognostic (3.05e-1)" "unprognostic (9.07e-2)" "unprognostic (1.96e-1)" "validated prognostic favorable (4.88e-7)" "validated prognostic favorable (1.89e-5)" "unprognostic (8.94e-2)" "unprognostic (3.43e-2)" "unprognostic (2.88e-3)" "unprognostic (1.55e-2)" "unprognostic (4.46e-2)" "unprognostic (2.19e-2)" "unprognostic (1.94e-2)" "unprognostic (2.58e-1)" "unprognostic (2.76e-3)" "unprognostic (3.40e-2)" "unprognostic (2.19e-2)" "unprognostic (2.27e-1)" "unprognostic (1.05e-1)" "unprognostic (6.44e-2)" "unprognostic (3.59e-1)" "unprognostic (2.52e-2)" "unprognostic (2.15e-1)" "unprognostic (6.69e-2)" "unprognostic (2.11e-2)" SLC16A5 "MCT5, MCT6" ENSG00000170190 "Solute carrier family 16 member 5" O15375 17 75087727-75106162 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 67.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 89.2;Loop of henle epithelial cells: 99.3;Papillary tip epithelial cells: 113.8;Renal collecting duct intercalated cells: 143.2;Renal collecting duct principal cells: 242.1;Respiratory ciliated cells: 70.4;Urothelial cells: 86.7" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 7.9;ependymal cell: 9.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 13.2;neutrophil: 35.1" "Group enriched" "Detected in all" 6 "granulocytes: 35.1;monocytes: 13.2" "Low cancer specificity" "Detected in many" "Liver - Vascular endothelial cells, Lung - Alveolar cells type 2, Spleen - Neutrophils_2, Stomach - Gastric mucous cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 2 "unprognostic (2.23e-1)" "unprognostic (7.23e-2)" "unprognostic (1.52e-1)" "unprognostic (4.24e-2)" "unprognostic (9.90e-2)" "unprognostic (8.39e-2)" "unprognostic (1.03e-1)" "unprognostic (4.43e-2)" "unprognostic (1.77e-1)" "unprognostic (5.60e-2)" "unprognostic (1.59e-1)" "unprognostic (8.10e-2)" "unprognostic (2.81e-2)" "unprognostic (3.97e-2)" "unprognostic (8.96e-2)" "unprognostic (2.49e-1)" "unprognostic (9.51e-2)" "unprognostic (1.10e-2)" "unprognostic (8.62e-3)" "unprognostic (5.94e-2)" "unprognostic (5.70e-2)" "unprognostic (2.45e-3)" "unprognostic (1.74e-2)" "unprognostic (3.94e-2)" "unprognostic (1.71e-2)" "unprognostic (2.07e-2)" "unprognostic (1.07e-1)" "unprognostic (3.95e-2)" "unprognostic (6.71e-2)" "unprognostic (4.11e-3)" "unprognostic (2.06e-1)" SLC16A6 "MCT6, MCT7" ENSG00000108932 "Solute carrier family 16 member 6" O15403 17 68267026-68291267 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 42.8;epididymis: 30.9;retina: 28.4" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 168.3;Endometrial glandular cells: 100.5;Epididymal principal cells: 92.5;Macrophages: 47.9;monocytes: 275.5;Neutrophils: 158.9;Rod photoreceptor cells: 59.6" "Group enriched" "Detected in many" 4 "choroid plexus epithelial cell: 155.4;endothelial cell: 39.9;fibroblast: 64.8" "Group enriched" "Detected in many" 5 "Breast Invasive Carcinoma (TCGA): 21.9;Skin Cutaneous Melanoma (TCGA): 20.3" "Region enriched" "Detected in all" 7 "choroid plexus: 108.0" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in all" 4 "skin cancer: 114.0" "Adrenal gland - Adrenal cortex cells, Lung - Macrophages, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054459, HPA066328" Uncertain Approved Vesicles NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 22: Epididymis - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 1 Vesicles "HPA054459: , HPA066328: " "unprognostic (7.98e-2)" "unprognostic (3.69e-2)" "unprognostic (1.00e-1)" "unprognostic (7.74e-3)" "unprognostic (5.17e-3)" "unprognostic (2.43e-1)" "unprognostic (4.40e-3)" "unprognostic (4.16e-3)" "unprognostic (5.46e-2)" "unprognostic (2.23e-1)" "unprognostic (1.03e-1)" "unprognostic (1.02e-2)" "unprognostic (7.49e-2)" "unprognostic (1.87e-1)" "unprognostic (3.62e-3)" "unprognostic (2.01e-1)" "unprognostic (1.57e-1)" "unprognostic (4.29e-1)" "unprognostic (3.46e-2)" "unprognostic (1.23e-2)" "unprognostic (4.00e-1)" "unprognostic (4.68e-2)" "unprognostic (4.70e-3)" "unprognostic (7.23e-2)" "unprognostic (1.83e-1)" "unprognostic (2.10e-1)" "unprognostic (5.99e-3)" "unprognostic (1.74e-1)" SLC16A7 MCT2 ENSG00000118596 "Solute carrier family 16 member 7" O60669 12 59596029-59789855 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 18.8;heart muscle: 32.2" "Cell type enhanced" "Detected in many" "Adipocytes: 749.1;Cardiomyocytes: 506.0;Distal convoluted tubule cells: 302.0;Parietal cells: 401.3" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 8 "Kidney Chromophobe (TCGA): 37.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Stomach - Parietal cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 30.2" HPA005911 Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 35: Non-specific - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 103: Non-specific - Basic cellular processes" 13 "Plasma membrane" Nucleoplasm "HPA005911: " "unprognostic (3.18e-2)" "unprognostic (5.87e-2)" "unprognostic (1.89e-1)" "unprognostic (2.35e-2)" "unprognostic (9.50e-2)" "unprognostic (2.32e-2)" "potential prognostic favorable (2.31e-4)" "unprognostic (4.37e-2)" "unprognostic (2.95e-2)" "unprognostic (2.39e-1)" "unprognostic (4.35e-2)" "unprognostic (7.55e-2)" "unprognostic (4.17e-2)" "unprognostic (3.95e-1)" "unprognostic (1.09e-1)" "unprognostic (1.60e-1)" "unprognostic (1.24e-1)" "unprognostic (2.82e-3)" "unprognostic (7.65e-2)" "unprognostic (3.84e-1)" "unprognostic (2.84e-1)" "unprognostic (4.45e-3)" "unprognostic (9.00e-3)" SLC16A8 "MCT3, REMP" ENSG00000100156 "Solute carrier family 16 member 8" O95907 22 38078134-38084184 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.4" "Cell type enriched" "Detected in many" 19 "Retinal pigment epithelial cells: 532.9" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 4.7" "Prostate - Prostate glandular cells, Spleen - Fibroblasts_2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA075017 Approved Approved "Intermediate filaments,Focal adhesion sites" No NA "Cluster 2: Non-specific - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" "Focal adhesion sites" "Intermediate filaments" "HPA075017: " "unprognostic (6.73e-2)" "unprognostic (2.90e-1)" "unprognostic (6.84e-2)" "unprognostic (1.70e-1)" "unprognostic (2.57e-2)" SLC16A9 "C10orf36, FLJ43803, MCT9" ENSG00000165449 "Solute carrier family 16 member 9" Q7RTY1 10 59650764-59736002 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 142.9;kidney: 178.4" "Group enriched" "Detected in many" 4 "Adrenal cortex cells: 850.0;Proximal tubule cells: 1103.2" "Group enriched" "Detected in many" 4 "astrocyte: 179.0;Bergmann glia: 66.5;choroid plexus epithelial cell: 162.3;ependymal cell: 102.2;upper rhombic lip: 67.1" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 45.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Stomach - Gastric mucous cells, Testis - Leydig cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049286 Approved Approved "Nucleoplasm,Cell Junctions" NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 88: Proximal tubular cells - Transmembrane transport" 3 Nucleoplasm "Cell Junctions" "HPA049286: " "unprognostic (4.71e-2)" "unprognostic (1.31e-1)" "unprognostic (2.80e-1)" "unprognostic (1.92e-1)" "unprognostic (1.94e-1)" "unprognostic (2.02e-2)" "unprognostic (2.38e-3)" "unprognostic (3.90e-3)" "unprognostic (6.00e-2)" "potential prognostic favorable (3.21e-8)" "unprognostic (1.34e-3)" "unprognostic (3.46e-3)" "unprognostic (7.19e-2)" "unprognostic (3.00e-2)" "unprognostic (1.97e-1)" "unprognostic (2.08e-2)" "potential prognostic favorable (4.66e-5)" "unprognostic (5.28e-2)" "unprognostic (1.46e-2)" "unprognostic (2.19e-1)" "unprognostic (1.01e-1)" "unprognostic (6.10e-2)" "unprognostic (1.98e-1)" "unprognostic (3.29e-3)" "unprognostic (2.45e-1)" "unprognostic (6.72e-2)" "unprognostic (1.18e-2)" "unprognostic (3.26e-1)" "unprognostic (9.50e-2)" SLC17A1 "NAPI-1, NPT1" ENSG00000124568 "Solute carrier family 17 member 1" Q14916 6 25782915-25832052 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 49 "kidney: 157.7;liver: 46.2" "Cell type enriched" "Detected in some" 32 "Proximal tubule cells: 1149.7" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney Renal Clear Cell Carcinoma (TCGA): 28.0;Kidney Renal Papillary Cell Carcinoma (TCGA): 44.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "Kidney cancer: 12.2" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA050513 Uncertain "Golgi apparatus" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 15: Kidney cancer - Membrane components" "Cluster 88: Proximal tubular cells - Transmembrane transport" "Golgi apparatus" "HPA050513: " "validated prognostic favorable (9.78e-6)" "validated prognostic favorable (4.58e-4)" "unprognostic (1.04e-1)" "unprognostic (1.60e-1)" "unprognostic (6.74e-2)" SLC17A2 NPT3 ENSG00000112337 "Solute carrier family 17 member 2" O00624 6 25912754-25930691 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 166 "liver: 74.4" "Cell type enriched" "Detected in some" 14 "Hepatocytes: 41.7" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Liver Hepatocellular Carcinoma (TCGA): 19.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA038270 Uncertain NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 18: Liver cancer - Metabolism" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "HPA038270: " "validated prognostic favorable (2.89e-6)" "validated prognostic favorable (9.00e-4)" "unprognostic (3.78e-1)" "potential prognostic favorable (7.39e-4)" "unprognostic (3.35e-2)" SLC17A3 NPT4 ENSG00000124564 "Solute carrier family 17 member 3" O00476 6 25833066-25882286 "Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "kidney: 153.3" "Cell type enriched" "Detected in some" 6 "Proximal tubule cells: 236.3" "Group enriched" "Detected in some" 4 "endothelial cell: 3.5;leukocyte: 1.2" "Group enriched" "Detected in some" 19 "Kidney Renal Clear Cell Carcinoma (TCGA): 197.1;Kidney Renal Papillary Cell Carcinoma (TCGA): 134.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 18 "Kidney cancer: 44.2" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 15: Kidney cancer - Membrane components" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "validated prognostic favorable (2.94e-6)" "validated prognostic favorable (1.43e-4)" "unprognostic (1.99e-1)" "unprognostic (1.67e-1)" "unprognostic (3.35e-1)" SLC17A4 KIAA2138 ENSG00000146039 "Solute carrier family 17 member 4" Q9Y2C5 6 25754699-25781199 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 8 "gallbladder: 15.3;intestine: 30.0;liver: 47.5;pancreas: 21.4" "Cell type enhanced" "Detected in some" "Cholangiocytes: 169.5;Colonocytes: 156.4;Enteric transient amplifying cells: 20.5;Enterocytes: 82.8;Goblet cells: 34.1;Hepatocytes: 73.2;Pancreatic duct cells: 57.2;Proximal tubule cells: 18.8" "Cell type enriched" "Detected in single" 8 "cerebellar inhibitory: 6.1" "Group enriched" "Detected in many" 7 "Kidney Renal Clear Cell Carcinoma (TCGA): 24.7;Liver Hepatocellular Carcinoma (TCGA): 18.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "prostate cancer: 3.0" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Region enriched" "Detected in single" 7 "cerebellum: 1.8" HPA055564 Approved NA NA "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 35: Non-specific - DNA binding" "Cluster 60: Prostate cancer - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" "HPA055564: " "unprognostic (1.71e-2)" "unprognostic (4.67e-2)" "validated prognostic favorable (8.98e-6)" "validated prognostic favorable (7.38e-5)" "unprognostic (9.44e-2)" "unprognostic (3.90e-2)" "potential prognostic favorable (7.89e-4)" "unprognostic (2.32e-1)" "unprognostic (5.37e-3)" "unprognostic (7.83e-2)" "unprognostic (1.06e-2)" "unprognostic (9.93e-2)" SLC17A5 "AST, ISSD, NSD, SD, SIALIN, SIASD, SLD" ENSG00000119899 "Solute carrier family 17 member 5" Q9NRA2 6 73593379-73653992 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "parathyroid gland: 292.0" "Cell type enhanced" "Detected in many" "Retinal ganglion cells: 181.6;Rod photoreceptor cells: 181.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Thyroid Carcinoma (TCGA): 73.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044479 Supported "Plasma membrane,Cytosol" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 45: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 2 "Plasma membrane, Cytosol" "HPA044479: " "unprognostic (1.55e-3)" "unprognostic (4.27e-3)" "unprognostic (5.80e-2)" "unprognostic (9.50e-3)" "unprognostic (1.83e-1)" "unprognostic (7.14e-2)" "unprognostic (2.00e-1)" "unprognostic (1.12e-1)" "unprognostic (3.59e-2)" "unprognostic (2.65e-1)" "potential prognostic favorable (5.00e-6)" "unprognostic (5.74e-2)" "unprognostic (5.52e-2)" "unprognostic (5.65e-3)" "unprognostic (2.43e-2)" "unprognostic (2.98e-1)" "unprognostic (9.79e-2)" "unprognostic (4.20e-1)" "unprognostic (1.82e-1)" "unprognostic (1.13e-1)" "unprognostic (2.65e-2)" "unprognostic (1.54e-2)" "unprognostic (1.05e-1)" "unprognostic (1.29e-1)" "unprognostic (1.45e-2)" "unprognostic (1.69e-1)" "unprognostic (1.76e-1)" "unprognostic (1.94e-1)" "unprognostic (7.40e-2)" "unprognostic (5.32e-2)" "unprognostic (1.04e-1)" SLC17A6 "DNPI, VGLUT2" ENSG00000091664 "Solute carrier family 17 member 6" Q9P2U8 11 22338381-22379503 "Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Neurotransmitter transport, Phosphate transport, Sodium transport, Symport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 15.6;pituitary gland: 3.5;retina: 7.3" "Group enriched" "Detected in some" 7 "Brain excitatory neurons: 47.7;Lactotrophs: 65.4;Other brain neurons: 30.6;Retinal ganglion cells: 77.3;Somatotrophs: 54.5;Thyrotrophs: 25.7" "Group enriched" "Detected in many" 4 "amygdala excitatory: 76.2;lower rhombic lip: 196.0;mammillary body: 152.0;splatter: 69.6;thalamic excitatory: 260.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 1.6;skin cancer: 1.1" "Pancreas - Beta cells" "Group enriched" "Detected in all" 5 "basal ganglia: 51.9;hypothalamus: 139.9;midbrain: 172.4;pons and medulla: 86.5;thalamus: 165.0" "Low region specificity" "Detected in all" "CAB037130, HPA039226, CAB078204" Supported Supported NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 49: Hindbrain - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 98: Neurons - Neurotransmission & signaling" "CAB037130: , CAB078204: , HPA039226: " "unprognostic (1.04e-1)" SLC17A7 "BNPI, VGLUT1" ENSG00000104888 "Solute carrier family 17 member 7" Q9P2U7 19 49429401-49442360 "Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Neurotransmitter transport, Phosphate transport, Sodium transport, Symport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 32 "brain: 385.5;retina: 292.9" "Group enriched" "Detected in some" 12 "Brain excitatory neurons: 119.7;Cone photoreceptor cells: 279.5;Retinal bipolar cells: 291.5;Rod photoreceptor cells: 229.5" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in some" 7 "Glioblastoma Multiforme (TCGA): 24.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 15.9" "Kidney - Fibroblasts, Lung - Fibroblasts_2, Minor Salivary Gland - Fibroblasts, Prostate - Endothelial cells, Skeletal muscle - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "amygdala: 265.6;cerebellum: 272.5;cerebral cortex: 444.1;hippocampal formation: 614.7" "CAB037183, HPA050458, HPA063679" Enhanced Supported NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 1 "CAB037183: , HPA050458: , HPA063679: " "unprognostic (6.13e-2)" "unprognostic (1.15e-1)" "unprognostic (3.25e-1)" "unprognostic (8.84e-2)" "unprognostic (3.25e-1)" "unprognostic (9.58e-2)" SLC17A8 "DFNA25, VGLUT3" ENSG00000179520 "Solute carrier family 17 member 8" Q8NDX2 12 100357074-100422055 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Hearing, Ion transport, Neurotransmitter transport, Phosphate transport, Sodium transport, Symport, Transport" "Chloride channel, Ion channel" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 4.9;lymphoid tissue: 1.3" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 27.2;Enterocytes: 46.1;Ependymal cells: 11.6;Epididymal efferent duct ciliated cells: 7.1;Extravillous trophoblasts: 12.4;Granulosa cells: 7.3;Kupffer cells: 7.2;Oligodendrocyte progenitor cells: 7.3;Other brain neurons: 18.2;Paneth cells: 11.6;Prostatic club cells: 11.1;Tuft cells: 11.5" "Cell type enhanced" "Detected in some" "CGE interneuron: 16.4;ependymal cell: 18.8" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "cerebral cortex: 24.1;midbrain: 18.5;pons: 14.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatic stellate cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA038870, CAB079058" Supported Approved "Endoplasmic reticulum" NA NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 24: Non-specific - Unknown function" "Cluster 1: Enterocytes - Absorption and Digestion" 1 "Endoplasmic reticulum" "CAB079058: , HPA038870: " "unprognostic (1.12e-2)" SLC17A9 "C20orf59, FLJ23412, VNUT" ENSG00000101194 "Solute carrier family 17 member 9" Q9BYT1 20 62952707-62969585 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 38.5" "Cell type enhanced" "Detected in many" "cDC: 14.0;Foveolar cells: 17.3;Gastric progenitor cells: 16.7;Goblet cells: 18.2;Hematopoietic stem cells: 20.9;Hepatocytes: 61.7;Hofbauer cells: 21.4;Microglia: 14.8;Plasma cells: 49.6" "Group enriched" "Detected in some" 9 "central nervous system macrophage: 22.4;leukocyte: 7.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 4.9" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Myeloma: 29.4" "Minor Salivary Gland - Plasma cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA047470 Approved Nucleoplasm NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 67: Plasma cells - Plasma cell differentiation" 6 Nucleoplasm "HPA047470: " "unprognostic (1.30e-1)" "unprognostic (2.37e-2)" "unprognostic (2.46e-1)" "unprognostic (9.11e-3)" "unprognostic (1.65e-1)" "unprognostic (1.42e-2)" "potential prognostic unfavorable (4.03e-4)" "unprognostic (1.75e-1)" "unprognostic (1.04e-2)" "potential prognostic unfavorable (1.68e-4)" "unprognostic (1.01e-2)" "unprognostic (1.92e-3)" "unprognostic (4.99e-2)" "unprognostic (1.25e-1)" "unprognostic (8.77e-3)" "unprognostic (1.17e-1)" "unprognostic (8.04e-2)" "unprognostic (5.02e-2)" "unprognostic (1.15e-2)" "unprognostic (1.15e-2)" "unprognostic (6.65e-2)" "unprognostic (2.48e-2)" "unprognostic (1.22e-1)" "unprognostic (9.36e-2)" "unprognostic (1.77e-1)" "unprognostic (6.88e-3)" "unprognostic (2.68e-2)" "unprognostic (6.71e-2)" "unprognostic (1.00e-2)" SLC18A1 "CGAT, VAT1, VMAT1" ENSG00000036565 "Solute carrier family 18 member A1" P54219 8 20144855-20183206 "FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "adrenal gland: 23.7" "Group enriched" "Detected in some" 19 "Adrenal medulla cells: 106.4;Neuroendocrine cells: 207.1" "Cell type enriched" "Detected in some" 4 "central nervous system macrophage: 6.5" "Cancer enhanced" "Detected in some" "Colon Adenocarcinoma (TCGA): 1.7;Stomach Adenocarcinoma (TCGA): 1.3" "Region enriched" "Detected in single" 20 "midbrain: 8.5" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 2.8" "Lineage enriched" "Detected in single" 19 "monocytes: 2.8" "Cancer enriched" "Detected in some" 10 "Neuroblastoma: 35.1" "Adrenal gland - Adrenal medulla cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA006877, HPA063797" Enhanced NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" 1 "HPA006877: , HPA063797: " "unprognostic (9.21e-3)" "unprognostic (1.21e-2)" "unprognostic (9.79e-3)" "unprognostic (7.48e-2)" "unprognostic (3.41e-1)" "unprognostic (1.34e-1)" "unprognostic (1.55e-1)" SLC18A2 "SVAT, SVMT, VMAT2" ENSG00000165646 "Solute carrier family 18 member A2" Q05940 10 117241093-117279430 "Disease related genes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Transport" "Disease variant, Dystonia, FDA approved drug targets, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.4;cervix: 28.1" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 138.3;Endometrial glandular cells: 307.0;Mast cells: 647.6;Neuroendocrine cells: 79.0;Other brain neurons: 67.3;Pancreatic islet cells: 59.1;Platelets: 87.5" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 32.5" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 8.2" "Group enriched" "Detected in many" 12 "hypothalamus: 47.5;midbrain: 173.0;pons: 150.4" "Immune cell enriched" "Detected in some" 15 "basophil: 59.5" "Lineage enriched" "Detected in many" 15 "granulocytes: 59.5" "Group enriched" "Detected in some" 5 "Leukemia: 9.7;Neuroblastoma: 7.0" "Adipose subcutaneous - Mast cells, Adipose visceral - Mast cells, Adrenal gland - Adrenal medulla cells, Colon - Mast cells, Lung - Mast cells, Testis - Spermatogonia" "Region enhanced" "Detected in many" "midbrain: 62.8" "Region enriched" "Detected in all" 4 "midbrain: 145.2" HPA073224 Enhanced Approved Vesicles,Centrosome NA NA "Cluster 41: Basophils - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 49: HMC-1 - Innate immune response" "Cluster 58: Mast cells - Allergic inflammatory responses" 10 "Vesicles, Centrosome" "HPA073224: " "unprognostic (1.02e-2)" "unprognostic (3.81e-1)" "unprognostic (1.96e-2)" "unprognostic (8.09e-2)" "potential prognostic favorable (8.93e-7)" "unprognostic (1.12e-2)" "unprognostic (2.97e-2)" "unprognostic (1.24e-2)" "potential prognostic favorable (6.60e-5)" "unprognostic (2.19e-1)" "unprognostic (2.10e-1)" "unprognostic (1.69e-1)" "unprognostic (1.27e-2)" "unprognostic (2.07e-1)" "unprognostic (3.41e-1)" "unprognostic (2.57e-3)" "unprognostic (4.07e-2)" "unprognostic (9.69e-2)" SLC18A3 VACHT ENSG00000187714 "Solute carrier family 18 member A3" Q16572 10 49610310-49612720 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Transport" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 5.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 4.4;Neuroblastoma: 14.7" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 5 "spinal cord: 102.5" CAB079011 Supported NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 43: Hindbrain - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" 2 "CAB079011: " "unprognostic (6.80e-2)" "potential prognostic unfavorable (1.15e-5)" "unprognostic (3.91e-2)" "unprognostic (2.23e-1)" SLC18B1 "C6orf192, dJ55C23.6" ENSG00000146409 "Solute carrier family 18 member B1" Q6NT16 6 132769370-132813339 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 143.2;Bergmann glia: 166.9;Choroid plexus epithelial cells: 125.2;Ependymal cells: 100.2;Hofbauer cells: 158.2" "Cell type enhanced" "Detected in all" "Bergmann glia: 181.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029747 Approved Approved "Golgi apparatus,Cytosol" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 39: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 4 "Golgi apparatus" Cytosol "HPA029747: " "unprognostic (4.63e-2)" "unprognostic (5.29e-2)" "unprognostic (1.75e-3)" "unprognostic (1.02e-2)" "unprognostic (3.02e-1)" "unprognostic (2.57e-2)" "unprognostic (6.48e-2)" "unprognostic (7.83e-3)" "unprognostic (1.91e-1)" "potential prognostic favorable (2.43e-5)" "unprognostic (3.01e-2)" "unprognostic (6.35e-2)" "unprognostic (1.42e-3)" "unprognostic (1.58e-2)" "unprognostic (4.30e-2)" "unprognostic (1.37e-1)" "unprognostic (6.64e-2)" "unprognostic (4.35e-1)" "unprognostic (6.23e-2)" "unprognostic (6.91e-2)" "unprognostic (1.67e-1)" "unprognostic (2.73e-1)" "unprognostic (8.17e-3)" "unprognostic (3.78e-1)" "unprognostic (1.96e-1)" "unprognostic (2.63e-2)" "unprognostic (1.65e-1)" "unprognostic (1.67e-2)" "unprognostic (3.18e-1)" SLC19A1 "FOLT, RFC1" ENSG00000173638 "Solute carrier family 19 member 1" P41440 21 45493572-45573365 "Cancer-related genes, Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Transport" "Cancer-related genes, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 44.8" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 341.0;Cytotrophoblasts: 207.5;Epicardial cells: 109.2;Migrating cytotrophoblasts: 81.9;Neutrophils: 139.8;Pericytes: 81.7;Retinal pigment epithelial cells: 85.3;Syncytiotrophoblasts: 444.1" "Cell type enriched" "Detected in all" 5 "pericyte: 1430.9" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "choroid plexus: 188.5" "Immune cell enriched" "Detected in many" 4 "neutrophil: 103.3" "Lineage enriched" "Detected in all" 6 "granulocytes: 103.3" "Low cancer specificity" "Detected in all" "Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024802 Approved Approved "Plasma membrane" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 47: Leukemia - Hemostasis" "Cluster 22: Non-specific - Basic cellular functions" 14 "Plasma membrane" "HPA024802: " "unprognostic (2.66e-1)" "potential prognostic unfavorable (8.84e-4)" "unprognostic (2.85e-1)" "potential prognostic unfavorable (3.07e-5)" "unprognostic (8.35e-2)" "unprognostic (6.98e-2)" "unprognostic (2.11e-1)" "unprognostic (2.69e-2)" "unprognostic (2.85e-2)" "unprognostic (2.22e-1)" "validated prognostic unfavorable (2.71e-6)" "validated prognostic unfavorable (8.88e-4)" "unprognostic (1.46e-2)" "unprognostic (1.98e-2)" "unprognostic (6.55e-3)" "unprognostic (9.16e-2)" "unprognostic (1.50e-1)" "unprognostic (3.08e-2)" "unprognostic (1.47e-1)" "unprognostic (4.67e-2)" "unprognostic (2.36e-1)" "unprognostic (1.68e-1)" "unprognostic (3.03e-1)" "unprognostic (1.31e-1)" "unprognostic (2.19e-2)" "unprognostic (7.25e-3)" "unprognostic (3.23e-1)" "unprognostic (9.17e-2)" "unprognostic (2.32e-1)" "potential prognostic unfavorable (8.17e-5)" "unprognostic (2.42e-2)" SLC19A2 "ThT1, THTR1, TRMA" ENSG00000117479 "Solute carrier family 19 member 2" O60779 1 169463909-169485944 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Deafness, Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 101.6;tongue: 79.4" "Cell type enhanced" "Detected in many" "Myonuclei: 254.1;Syncytiotrophoblasts: 361.1;Urothelial cells: 274.4" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 94.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006119, HPA016599" Uncertain Approved Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 103: Non-specific - Basic cellular processes" 30 Cytosol "HPA006119: , HPA016599: " "unprognostic (8.41e-2)" "unprognostic (3.83e-2)" "unprognostic (2.54e-1)" "unprognostic (2.54e-2)" "unprognostic (3.26e-1)" "unprognostic (1.59e-1)" "unprognostic (4.29e-2)" "unprognostic (3.57e-2)" "unprognostic (6.54e-2)" "unprognostic (1.32e-2)" "unprognostic (1.05e-2)" "unprognostic (1.55e-2)" "unprognostic (8.67e-2)" "unprognostic (1.66e-1)" "unprognostic (3.46e-1)" "unprognostic (1.11e-1)" "unprognostic (1.97e-1)" "unprognostic (7.51e-2)" "unprognostic (3.67e-1)" "unprognostic (2.61e-1)" "unprognostic (3.41e-2)" "unprognostic (2.35e-1)" "unprognostic (2.66e-2)" "unprognostic (5.18e-2)" "unprognostic (2.28e-1)" "potential prognostic favorable (2.26e-4)" "unprognostic (5.21e-3)" "unprognostic (2.84e-1)" "unprognostic (5.54e-2)" "unprognostic (1.66e-2)" "unprognostic (4.45e-1)" SLC19A3 THTR2 ENSG00000135917 "Solute carrier family 19 member 3" Q9BZV2 2 227683763-227718028 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 43.6;breast: 18.5;placenta: 22.6" "Cell type enhanced" "Detected in many" "Adipocytes: 671.8;Cytotrophoblasts: 137.2;Distal convoluted tubule cells: 197.3;Migrating cytotrophoblasts: 72.1;Syncytiotrophoblasts: 310.5" "Cell type enriched" "Detected in many" 16 "endothelial cell: 265.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 6.9" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "liver cancer: 10.0" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Minor Salivary Gland - Adipocytes (Minor salivary gland), Skin - Adipocytes (Skin)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038898 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 18: Liver cancer - Metabolism" "Cluster 89: Adipocytes - Lipid metabolism" 10 "Nucleoplasm, Plasma membrane" Cytosol "HPA038898: " "unprognostic (4.21e-1)" "unprognostic (7.79e-2)" "potential prognostic favorable (2.15e-4)" "unprognostic (3.27e-2)" "unprognostic (2.96e-1)" "unprognostic (8.67e-2)" "unprognostic (9.95e-2)" "unprognostic (6.07e-2)" "potential prognostic unfavorable (6.59e-4)" "unprognostic (2.39e-2)" "unprognostic (1.43e-1)" "unprognostic (2.77e-1)" "unprognostic (9.51e-3)" "unprognostic (3.36e-2)" "unprognostic (2.26e-1)" "unprognostic (1.12e-1)" "unprognostic (2.71e-2)" "unprognostic (8.52e-2)" "unprognostic (1.46e-2)" "unprognostic (5.65e-2)" "unprognostic (9.27e-2)" "unprognostic (1.32e-2)" "unprognostic (2.29e-1)" "unprognostic (6.13e-3)" "potential prognostic favorable (8.38e-5)" "unprognostic (2.34e-1)" "unprognostic (3.01e-1)" "unprognostic (7.96e-2)" "unprognostic (5.00e-3)" SLC1A1 "EAAC1, EAAT3, hEAAC1" ENSG00000106688 "Solute carrier family 1 member 1" P43005 9 4490468-4587469 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Disease variant, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 42.5;intestine: 60.9;kidney: 47.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 231.3;Endometrial glandular cells: 408.5;Enterocytes: 358.1;Epicardial cells: 211.5;Hepatocytes: 225.9;Oligodendrocyte progenitor cells: 276.4;Pituicytes/FSCs: 398.4;Proximal tubule cells: 417.7" "Cell type enhanced" "Detected in all" "endothelial cell: 497.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Alveolar cells type 1, Prostate - Smooth muscle cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062356 Enhanced NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 29: Forebrain - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 51: Secretory epithelial cells - Mixed function" 114 "HPA062356: " "unprognostic (1.13e-2)" "unprognostic (7.58e-3)" "unprognostic (5.60e-2)" "unprognostic (5.76e-2)" "unprognostic (1.67e-2)" "unprognostic (2.54e-1)" "unprognostic (7.41e-2)" "potential prognostic favorable (2.12e-5)" "unprognostic (8.07e-2)" "unprognostic (2.53e-2)" "potential prognostic favorable (2.84e-14)" "unprognostic (6.18e-3)" "unprognostic (2.10e-2)" "unprognostic (8.93e-2)" "potential prognostic favorable (2.63e-4)" "unprognostic (1.84e-2)" "unprognostic (9.45e-2)" "unprognostic (1.50e-1)" "unprognostic (6.47e-2)" "unprognostic (2.05e-1)" "unprognostic (3.89e-1)" "unprognostic (4.48e-2)" "unprognostic (3.99e-1)" "unprognostic (7.86e-3)" "unprognostic (2.67e-2)" "unprognostic (7.04e-2)" "unprognostic (1.01e-1)" "unprognostic (2.70e-1)" "unprognostic (1.61e-1)" "unprognostic (4.04e-2)" "unprognostic (3.03e-1)" SLC1A2 "EAAT2, GLT-1, GLT1, HBGT" ENSG00000110436 "Solute carrier family 1 member 2" P43004 11 35251205-35420063 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 18 "brain: 1024.9" "Cell type enriched" "Detected in many" 6 "Astrocytes: 6365.0" "Cell type enriched" "Detected in all" 4 "astrocyte: 5025.1" "Cancer enriched" "Detected in some" 7 "Glioblastoma Multiforme (TCGA): 93.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.3" "Cancer enhanced" "Detected in some" "Gastric cancer: 6.4;Neuroblastoma: 4.0" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Stomach - Chief cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002574, HPA009172, HPA067499" Enhanced NA NA 18000 "Cluster 78: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 28: Astrocytes - Homeostasis & neuron support" 3 "CAB002574: , HPA009172: , HPA067499: " "unprognostic (6.52e-3)" "unprognostic (1.75e-1)" "unprognostic (2.00e-1)" "unprognostic (1.98e-3)" "unprognostic (8.80e-2)" "unprognostic (1.38e-2)" "unprognostic (1.28e-1)" "unprognostic (1.90e-1)" "unprognostic (2.88e-1)" SLC1A3 "EA6, EAAT1, GLAST, GLAST-1, GLAST1" ENSG00000079215 "Solute carrier family 1 member 3" P43003 5 36596588-36688334 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "brain: 527.4;retina: 204.7" "Cell type enhanced" "Detected in many" "Astrocytes: 2441.8;Bergmann glia: 5598.1;Ependymal cells: 1345.4;Macrophages: 622.7;Microglia: 1556.7;Müller glia: 1039.7;Pituicytes/FSCs: 1168.0" "Cell type enhanced" "Detected in many" "astrocyte: 2138.5;Bergmann glia: 5853.4;central nervous system macrophage: 1971.9;ependymal cell: 1856.5" "Cancer enriched" "Detected in all" 23 "Glioblastoma Multiforme (TCGA): 484.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "classical monocyte: 1.5;intermediate monocyte: 1.2;myeloid DC: 1.6" "Group enriched" "Detected in many" 16 "dendritic cells: 1.6;monocytes: 1.5" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Macrophages, Breast - Adipocytes (Breast), Kidney - Macrophages, Lung - Macrophages, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Spleen - Macrophages, Stomach - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002573, HPA037467, HPA037468" Enhanced Supported Approved Nucleoli,Vesicles NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 73: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 20 "Nucleoli, Vesicles" "CAB002573: , HPA037467: , HPA037468: " "unprognostic (4.29e-1)" "unprognostic (6.41e-2)" "unprognostic (4.48e-1)" "unprognostic (4.01e-2)" "unprognostic (4.33e-2)" "unprognostic (2.26e-3)" "unprognostic (1.16e-1)" "unprognostic (1.78e-3)" "unprognostic (3.64e-2)" "unprognostic (7.08e-2)" "unprognostic (1.25e-2)" "unprognostic (1.77e-1)" "unprognostic (2.72e-3)" "unprognostic (4.13e-3)" "unprognostic (1.35e-1)" "unprognostic (3.11e-2)" "unprognostic (5.21e-3)" "unprognostic (2.48e-1)" "unprognostic (1.87e-1)" "unprognostic (2.14e-1)" "unprognostic (1.82e-1)" "unprognostic (1.10e-2)" "unprognostic (1.11e-1)" "unprognostic (7.00e-2)" "unprognostic (4.51e-2)" "unprognostic (2.67e-2)" "unprognostic (9.07e-2)" "unprognostic (1.84e-1)" "unprognostic (3.75e-1)" "unprognostic (2.52e-2)" "unprognostic (2.11e-1)" SLC1A4 "ASCT-1, ASCT1, SATT" ENSG00000115902 "Solute carrier family 1 member 4" P43007 2 64988477-65023865 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Symport, Transport" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 49.2" "Cell type enhanced" "Detected in many" "Astrocytes: 145.9;Gonadotrophs: 102.3;Melanocytes: 245.3;pDCs: 119.6;Plasma cells: 110.1;Thymocytes: 110.9" "Cell type enhanced" "Detected in all" "astrocyte: 152.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Myeloma: 90.8;skin cancer: 116.0" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Pituitary gland - Gonadotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034963, HPA034964" Enhanced Enhanced Centrosome NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 78: Brain - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 9: T-cells - Adaptive immunity: Regulation" 8 Centrosome "HPA034963: , HPA034964: " "unprognostic (5.06e-3)" "unprognostic (1.83e-1)" "unprognostic (9.85e-2)" "unprognostic (1.29e-2)" "unprognostic (5.43e-2)" "unprognostic (7.29e-2)" "unprognostic (6.56e-2)" "potential prognostic favorable (4.56e-4)" "unprognostic (1.81e-2)" "unprognostic (2.78e-3)" "potential prognostic favorable (3.75e-5)" "unprognostic (8.98e-3)" "unprognostic (2.66e-1)" "validated prognostic unfavorable (8.59e-5)" "validated prognostic unfavorable (3.00e-5)" "unprognostic (2.22e-2)" "unprognostic (1.38e-2)" "unprognostic (5.28e-2)" "unprognostic (2.26e-2)" "unprognostic (1.19e-1)" "unprognostic (4.58e-3)" "unprognostic (1.17e-2)" "unprognostic (1.00e-1)" "unprognostic (7.16e-2)" "unprognostic (7.27e-2)" "unprognostic (1.65e-1)" "unprognostic (2.14e-1)" "unprognostic (1.85e-3)" "unprognostic (5.41e-1)" "unprognostic (2.07e-1)" "potential prognostic favorable (1.90e-4)" SLC1A5 "AAAT, ASCT2, M7V1, RDRC" ENSG00000105281 "Solute carrier family 1 member 5" Q15758 19 46774883-46788594 "FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Antiport, Host-virus interaction, Symport, Transport" "Host cell receptor for virus entry, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 157.5;Extravillous trophoblasts: 177.6;Prostatic hillock cells: 188.0" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 30.1;leukocyte: 12.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 96.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Minor Salivary Gland - Minor salivary gland ductal cells, Prostate - Prostate basal glandular cells, Skin - Eccrine sweat gland cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA035239, HPA035240" Enhanced Supported "Plasma membrane,Centriolar satellite,Basal body" NA NA 27000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 103: Non-specific - Basic cellular processes" 33 "Plasma membrane" "Centriolar satellite, Basal body" "HPA035239: , HPA035240: " "unprognostic (1.16e-1)" "unprognostic (1.19e-3)" "unprognostic (1.32e-1)" "unprognostic (1.23e-1)" "unprognostic (1.79e-2)" "unprognostic (9.91e-3)" "unprognostic (1.30e-1)" "unprognostic (1.88e-2)" "unprognostic (6.83e-2)" "unprognostic (2.76e-1)" "potential prognostic unfavorable (2.20e-7)" "unprognostic (1.12e-2)" "unprognostic (1.24e-1)" "potential prognostic unfavorable (2.14e-10)" "unprognostic (4.21e-3)" "unprognostic (1.46e-3)" "unprognostic (1.06e-2)" "unprognostic (6.65e-2)" "unprognostic (1.39e-1)" "unprognostic (8.07e-3)" "unprognostic (2.91e-2)" "unprognostic (2.71e-2)" "unprognostic (1.27e-1)" "unprognostic (2.53e-2)" "unprognostic (1.03e-1)" "unprognostic (3.04e-1)" "unprognostic (8.69e-3)" "unprognostic (1.52e-2)" "unprognostic (1.34e-1)" "unprognostic (8.91e-2)" "unprognostic (3.88e-1)" SLC1A6 EAAT4 ENSG00000105143 "Solute carrier family 1 member 6" P48664 19 14950033-15022990 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 105.2" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 18.2;Brain inhibitory neurons: 20.3;Early spermatids: 52.6;Extravillous trophoblasts: 17.4;Late primary spermatocytes: 48.4;Late spermatids: 115.6;Other brain neurons: 18.9;Retinal horizontal cells: 24.0;Sertoli cells: 41.7;Syncytiotrophoblasts: 58.1" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in many" 7 "Bladder Urothelial Carcinoma (TCGA): 45.4" "Region enriched" "Detected in all" 5 "cerebellum: 159.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder cancer: 8.1;breast cancer: 8.4" "Pituitary gland - Gonadotropes, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Testis - Sertoli cells" "Region enriched" "Detected in all" 6 "cerebellum: 136.3" "Region enhanced" "Detected in all" "cerebellum: 70.8" "HPA041505, HPA044066" Enhanced Supported Supported "Plasma membrane,Intermediate filaments" NA NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" "Plasma membrane" "Intermediate filaments" "HPA041505: , HPA044066: " "unprognostic (1.05e-3)" "unprognostic (7.21e-2)" "unprognostic (4.29e-1)" "unprognostic (3.63e-1)" "unprognostic (1.53e-1)" "unprognostic (1.83e-1)" "potential prognostic favorable (9.69e-5)" "unprognostic (7.24e-3)" "unprognostic (2.47e-1)" "unprognostic (5.07e-2)" "unprognostic (4.62e-2)" "potential prognostic favorable (4.47e-4)" "unprognostic (1.34e-1)" "unprognostic (1.96e-3)" SLC1A7 EAAT5 ENSG00000162383 "Solute carrier family 1 member 7" O00341 1 53087179-53142638 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "retina: 37.4" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 126.3;Epicardial cells: 45.5;Fibro-adipogenic progenitors: 60.6;Retinal bipolar cells: 378.6;Rod photoreceptor cells: 147.0" "Cell type enriched" "Detected in some" 4 "endothelial cell: 53.8" "Group enriched" "Detected in some" 4 "Liver Hepatocellular Carcinoma (TCGA): 1.6;Lung Adenocarcinoma (TCGA): 5.2" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "gdT-cell: 2.2" "Lineage enriched" "Detected in single" 22 "T-cells: 2.2" "Cancer enhanced" "Detected in some" "Brain cancer: 4.1;breast cancer: 5.6" "Breast - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblasts_2, Prostate - Fibroblasts, Skin - Fibroblasts_2, Stomach - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA049124 Enhanced NA NA "Cluster 24: Non-specific - Transcription" "Cluster 42: Retina - Visual perception" "Cluster 47: Endothelial cells - Vasculature" "Cluster 1: Neuronal - Visual perception" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "HPA049124: " "unprognostic (4.27e-2)" "unprognostic (2.41e-1)" "unprognostic (2.74e-2)" "unprognostic (3.51e-1)" "unprognostic (5.89e-3)" "unprognostic (5.35e-2)" "unprognostic (4.43e-2)" "unprognostic (3.37e-2)" SLC20A1 "Glvr-1, GLVR1, PiT-1, PiT1" ENSG00000144136 "Solute carrier family 20 member 1" Q8WUM9 2 112645939-112663825 "Metabolic proteins, Predicted membrane proteins, Transporters" "Host-virus interaction, Phosphate transport, Symport, Transport" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 373.5;Endometrial glandular cells: 368.9;Epicardial cells: 434.4;Ocular epithelial cells: 948.8;Prostatic hillock cells: 417.1;Urothelial cells: 797.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019279, HPA035834, HPA064386" Approved Supported "Plasma membrane" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 37: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 100: Stratified epithelial cells - Barrier functions" 31 "Plasma membrane" "CAB019279: , HPA035834: , HPA064386: " "unprognostic (8.26e-2)" "unprognostic (2.88e-1)" "unprognostic (3.72e-1)" "unprognostic (2.82e-2)" "unprognostic (6.63e-2)" "unprognostic (1.18e-1)" "unprognostic (2.48e-1)" "unprognostic (1.34e-1)" "unprognostic (2.11e-3)" "unprognostic (3.65e-1)" "unprognostic (1.43e-2)" "unprognostic (2.99e-2)" "unprognostic (5.01e-2)" "potential prognostic unfavorable (7.36e-4)" "unprognostic (3.37e-2)" "unprognostic (1.01e-3)" "unprognostic (1.91e-2)" "unprognostic (1.75e-1)" "unprognostic (1.69e-1)" "unprognostic (5.41e-2)" "unprognostic (1.52e-2)" "unprognostic (2.50e-2)" "potential prognostic unfavorable (2.89e-4)" "unprognostic (5.54e-2)" "unprognostic (8.83e-2)" "potential prognostic favorable (6.73e-4)" "unprognostic (4.76e-2)" "unprognostic (1.73e-1)" "unprognostic (1.30e-1)" "unprognostic (6.30e-2)" "unprognostic (3.61e-2)" SLC20A2 "Glvr-2, GLVR2, MLVAR, PiT-2, Ram-1" ENSG00000168575 "Solute carrier family 20 member 2" Q08357 8 42416475-42541926 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Host-virus interaction, Ion transport, Phosphate transport, Sodium transport, Symport, Transport" "Host cell receptor for virus entry, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 146.2;skeletal muscle: 122.9" "Cell type enhanced" "Detected in all" "Choroid plexus epithelial cells: 1280.4;Endometrial glandular cells: 703.5;Myonuclei: 1452.7;Urothelial cells: 882.6" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 1102.2;pericyte: 2226.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026540 Approved NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 55: Myocytes - Oxidative muscle function" 5 "HPA026540: " "unprognostic (8.31e-2)" "potential prognostic unfavorable (3.13e-4)" "unprognostic (7.88e-2)" "unprognostic (1.50e-1)" "unprognostic (3.99e-2)" "unprognostic (3.38e-2)" "unprognostic (8.20e-2)" "unprognostic (3.69e-2)" "unprognostic (2.12e-1)" "unprognostic (9.11e-2)" "potential prognostic favorable (3.91e-6)" "unprognostic (1.85e-2)" "unprognostic (1.65e-1)" "unprognostic (2.32e-1)" "unprognostic (9.12e-3)" "unprognostic (2.30e-1)" "unprognostic (2.87e-1)" "unprognostic (1.64e-1)" "unprognostic (7.10e-2)" "unprognostic (1.23e-2)" "unprognostic (9.87e-2)" "unprognostic (1.05e-1)" "unprognostic (1.05e-1)" "unprognostic (5.19e-2)" "unprognostic (1.83e-1)" "unprognostic (2.00e-2)" "unprognostic (1.76e-1)" "unprognostic (9.19e-2)" "unprognostic (2.09e-1)" "unprognostic (5.47e-2)" "unprognostic (8.32e-3)" SLC22A1 OCT1 ENSG00000175003 "Solute carrier family 22 member 1" O15245 6 160121815-160158718 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 400 "liver: 595.7" "Cell type enriched" "Detected in many" 10 "Hepatocytes: 1217.8" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in some" 65 "Liver Hepatocellular Carcinoma (TCGA): 112.9" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 12 "neutrophil: 3.5" "Lineage enriched" "Detected in single" 12 "granulocytes: 3.5" "Not detected" "Not detected" "Liver - Hepatocytes, Spleen - Neutrophils_2" "Not detected" "Not detected" "Not detected" "Not detected" HPA029846 Approved NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 53: Liver - Plasma proteins" "Cluster 51: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 93: Hepatocytes - Bile production & excretion" 4 "HPA029846: " "unprognostic (1.11e-2)" "unprognostic (1.93e-2)" "unprognostic (6.09e-3)" "validated prognostic favorable (3.96e-5)" "validated prognostic favorable (9.29e-8)" "unprognostic (8.48e-3)" SLC22A10 "hOAT5, OAT5" ENSG00000184999 "Solute carrier family 22 member 10" Q63ZE4 11 63268022-63311783 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 286 "liver: 94.9" "Group enriched" "Detected in some" 4 "Brain excitatory neurons: 70.1;Brain inhibitory neurons: 20.2;Hepatocytes: 35.3;Proximal tubule cells: 24.0" "Cell type enhanced" "Detected in many" "deep-layer corticothalamic and 6b: 264.6;deep-layer intratelencephalic: 197.5;upper-layer intratelencephalic: 351.6" "Cancer enriched" "Detected in single" 13 "Liver Hepatocellular Carcinoma (TCGA): 6.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells" "Not detected" "Not detected" NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 53: Neurons - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" "unprognostic (1.86e-3)" "unprognostic (4.55e-2)" SLC22A11 OAT4 ENSG00000168065 "Solute carrier family 22 member 11" Q9NSA0 11 64555690-64572875 "FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Anion exchange, Antiport, Ion transport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 69 "epididymis: 10.0;kidney: 36.1;placenta: 31.4" "Group enriched" "Detected in some" 4 "Cytotrophoblasts: 836.1;Syncytiotrophoblasts: 2300.3" "Cell type enriched" "Detected in single" 4 "fibroblast: 1.1" "Group enriched" "Detected in some" 5 "Kidney Renal Clear Cell Carcinoma (TCGA): 49.2;Kidney Renal Papillary Cell Carcinoma (TCGA): 46.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells" "Not detected" "Not detected" HPA026076 Enhanced NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 1 "HPA026076: " "unprognostic (1.52e-1)" "unprognostic (3.03e-1)" "unprognostic (3.70e-2)" "validated prognostic favorable (2.59e-9)" "validated prognostic favorable (6.99e-4)" "potential prognostic favorable (2.66e-4)" "unprognostic (1.82e-1)" "unprognostic (1.43e-1)" "unprognostic (1.37e-1)" "unprognostic (1.47e-1)" SLC22A12 "OAT4L, RST, URAT1" ENSG00000197891 "Solute carrier family 22 member 12" Q96S37 11 64590641-64602353 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 205 "kidney: 103.6" "Cell type enriched" "Detected in some" 10 "Proximal tubule cells: 103.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Kidney Renal Clear Cell Carcinoma (TCGA): 29.2;Kidney Renal Papillary Cell Carcinoma (TCGA): 36.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA024575 Enhanced NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 15: Non-specific - Transcription" "Cluster 7: Liver cancer - Metabolism" "Cluster 88: Proximal tubular cells - Transmembrane transport" 1 "HPA024575: " "validated prognostic favorable (2.02e-6)" "validated prognostic favorable (6.02e-4)" "unprognostic (2.40e-2)" "unprognostic (2.57e-1)" "unprognostic (5.92e-2)" SLC22A13 "OAT10, OCTL1, OCTL3, ORCTL3" ENSG00000172940 "Solute carrier family 22 member 13" Q9Y226 3 38265812-38278757 "Metabolic proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 29 "kidney: 8.4" "Cell type enhanced" "Detected in some" "cDC: 5.5;Endometrial glandular cells: 6.3;Endometrial luminal cells: 6.1;Esophageal apical cells: 3.7;monocytes: 4.6;Neutrophils: 6.9;Respiratory ionocytes: 5.1;Retinal ganglion cells: 3.9;Retinal horizontal cells: 6.0;Urothelial cells: 4.3" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in single" "Kidney Renal Papillary Cell Carcinoma (TCGA): 1.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA035603, HPA035962" Enhanced NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 37: Neurons - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" "HPA035603: , HPA035962: " "unprognostic (6.28e-3)" SLC22A14 "OCTL2, ORCTL4" ENSG00000144671 "Solute carrier family 22 member 14" Q9Y267 3 38282294-38318575 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 10.9" "Group enriched" "Detected in many" 6 "Early spermatids: 92.3;Late primary spermatocytes: 48.2;Late spermatids: 174.0" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA037556 Approved "Perinuclear theca,Connecting piece,Mid piece,Principal piece" NA NA "Cluster 67: Testis - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 2 "Connecting piece, Mid piece, Principal piece" "Perinuclear theca" "HPA037556: " SLC22A15 FLIPT1 ENSG00000163393 "Solute carrier family 22 member 15" Q8IZD6 1 115976513-116070054 "Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 29.0" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 159.3;Ependymal cells: 194.8;Monocyte progenitors: 203.3;Neutrophil progenitors: 653.5;Neutrophils: 630.1;Oligodendrocytes: 355.6" "Cell type enhanced" "Detected in all" "oligodendrocyte: 472.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 1.3;non-classical monocyte: 1.2" "Group enriched" "Detected in many" 8 "granulocytes: 1.3;monocytes: 1.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019785 Uncertain NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 8 "HPA019785: " "unprognostic (1.52e-1)" "unprognostic (2.32e-1)" "unprognostic (7.76e-2)" "unprognostic (1.22e-2)" "unprognostic (1.56e-2)" "unprognostic (8.13e-3)" "unprognostic (1.60e-2)" "unprognostic (6.34e-3)" "unprognostic (1.69e-1)" "unprognostic (1.11e-2)" "potential prognostic unfavorable (5.87e-4)" "unprognostic (9.90e-2)" "unprognostic (2.03e-2)" "potential prognostic unfavorable (2.43e-5)" "unprognostic (1.86e-1)" "unprognostic (1.15e-2)" "unprognostic (3.30e-1)" "unprognostic (1.03e-1)" "unprognostic (2.82e-2)" "unprognostic (4.30e-2)" "unprognostic (4.38e-2)" "unprognostic (1.22e-1)" "unprognostic (1.18e-1)" "unprognostic (9.89e-2)" "unprognostic (3.25e-1)" "unprognostic (9.77e-3)" "unprognostic (4.48e-2)" "unprognostic (5.94e-3)" SLC22A16 "CT2, FLIPT2, OAT6, OKB1" ENSG00000004809 "Solute carrier family 22 member 16" Q86VW1 6 110424687-110476641 "Metabolic proteins, Predicted membrane proteins, Transporters" "Differentiation, Ion transport, Spermatogenesis, Transport" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 19.3;testis: 20.0" "Cell type enhanced" "Detected in some" "Early spermatids: 36.0;Erythrocyte progenitors: 119.9;Hematopoietic stem cells: 49.5;Late primary spermatocytes: 112.5;Late spermatids: 45.8;Megakaryocyte progenitors: 18.1;Monocyte progenitors: 32.2;Neutrophil progenitors: 45.1;Thymocytes: 22.0" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "Uterine Corpus Endometrial Carcinoma (TCGA): 3.6" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "basophil: 5.8;classical monocyte: 7.0" "Group enriched" "Detected in many" 56 "dendritic cells: 4.0;granulocytes: 5.8;monocytes: 7.0" "Cancer enriched" "Detected in single" 11 "Leukemia: 10.5" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA036902 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 2 "Plasma membrane, Cytosol" "HPA036902: " "unprognostic (2.89e-2)" SLC22A17 "BOCT, BOIT, NGALR" ENSG00000092096 "Solute carrier family 22 member 17" Q8WUG5 14 23346314-23352912 "Predicted membrane proteins, Transporters" "Ion transport, Iron transport, Transport" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 276.8;choroid plexus: 234.8;pituitary gland: 178.3" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 121.2;Brain inhibitory neurons: 170.6;Corticotrophs: 160.3;Ependymal cells: 127.1;Oligodendrocyte progenitor cells: 178.3;Other brain neurons: 279.8;Pancreatic islet cells: 210.1;Prostatic glandular cells: 169.4;Retinal horizontal cells: 114.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 145.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 30.2" "Adrenal gland - Adrenal medulla cells, Breast - Breast glandular cells, Colon - Enteric glia cells, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Alpha cells, Prostate - Prostate glandular cells, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002728 Uncertain NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 98: Neurons - Neurotransmission & signaling" 1 "HPA002728: " "unprognostic (4.06e-2)" "unprognostic (2.41e-1)" "unprognostic (1.46e-1)" "unprognostic (8.18e-3)" "unprognostic (2.85e-2)" "unprognostic (7.18e-2)" "unprognostic (8.38e-2)" "unprognostic (1.67e-2)" "unprognostic (2.09e-2)" "unprognostic (3.40e-3)" "unprognostic (1.34e-1)" "unprognostic (3.63e-1)" "unprognostic (1.02e-2)" "unprognostic (1.62e-1)" "unprognostic (1.24e-2)" "unprognostic (8.59e-3)" "unprognostic (1.95e-1)" "unprognostic (8.09e-3)" "unprognostic (2.28e-1)" "unprognostic (1.20e-1)" "unprognostic (3.95e-1)" "potential prognostic favorable (6.86e-4)" "unprognostic (3.44e-1)" "unprognostic (1.10e-1)" "unprognostic (9.00e-3)" "unprognostic (2.14e-2)" "unprognostic (1.39e-1)" "potential prognostic unfavorable (7.25e-4)" "unprognostic (1.06e-1)" "unprognostic (7.13e-2)" "potential prognostic unfavorable (5.60e-4)" SLC22A18 "BWR1A, BWSCR1A, IMPT1, ITM, ORCTL2, SLC22A1L, TSSC5" ENSG00000110628 "Solute carrier family 22 member 18" Q96BI1 11 2899721-2925246 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 48.1;liver: 80.8" "Cell type enhanced" "Detected in many" "Colonocytes: 198.8;Cytotrophoblasts: 90.9;Early spermatids: 141.0;Enterocytes: 540.5;Hepatocytes: 100.1;Late spermatids: 684.6;Syncytiotrophoblasts: 142.0" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 11.9;vascular associated smooth muscle cell: 12.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Stomach - Gastric mucous cells, Testis - Late spermatids" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA067812, HPA071461" Enhanced Approved "Plasma membrane" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 53: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 14 "Plasma membrane" "HPA067812: , HPA071461: " "unprognostic (1.12e-2)" "unprognostic (1.03e-1)" "unprognostic (1.85e-1)" "unprognostic (2.14e-2)" "unprognostic (3.16e-3)" "unprognostic (2.17e-2)" "unprognostic (8.25e-2)" "unprognostic (3.96e-2)" "unprognostic (2.59e-2)" "unprognostic (7.25e-2)" "unprognostic (3.71e-1)" "unprognostic (1.22e-1)" "unprognostic (5.31e-2)" "unprognostic (6.39e-2)" "unprognostic (9.05e-2)" "unprognostic (2.80e-2)" "unprognostic (1.03e-2)" "unprognostic (8.41e-3)" "unprognostic (3.51e-1)" "unprognostic (8.58e-3)" "unprognostic (3.20e-2)" "unprognostic (1.35e-1)" "unprognostic (2.19e-1)" "unprognostic (2.26e-1)" "unprognostic (1.12e-2)" "unprognostic (2.03e-2)" "unprognostic (2.77e-1)" "unprognostic (3.07e-1)" "unprognostic (2.02e-2)" "unprognostic (2.46e-1)" "unprognostic (2.58e-2)" SLC22A2 OCT2 ENSG00000112499 "Solute carrier family 22 member 2" O15244 6 160171061-160277638 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 80 "kidney: 143.6" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 16.0;Early spermatids: 18.4;Loop of henle epithelial cells: 38.6;Podocytes: 10.6;Proximal tubule cells: 111.9;Renal connecting tubule cells: 19.7;Tuft cells: 11.5" "Cell type enriched" "Detected in some" 8 "fibroblast: 27.0" "Group enriched" "Detected in some" 8 "Kidney Renal Clear Cell Carcinoma (TCGA): 124.4;Kidney Renal Papillary Cell Carcinoma (TCGA): 107.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney cancer: 3.4;prostate cancer: 1.3" "Adipose subcutaneous - Smooth muscle cells, Kidney - Proximal tubular cells" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "midbrain: 2.5" "HPA008549, CAB068236, CAB068237" Enhanced NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 88: Proximal tubular cells - Transmembrane transport" 4 "CAB068236: , CAB068237: , HPA008549: " "unprognostic (9.98e-2)" "validated prognostic favorable (5.58e-12)" "validated prognostic favorable (1.56e-4)" "potential prognostic favorable (4.43e-8)" SLC22A23 "C6orf85, FLJ22174" ENSG00000137266 "Solute carrier family 22 member 23" A1A5C7 6 3268962-3457050 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Foveolar cells: 612.4;Goblet cells: 380.9;Late spermatids: 429.1;Prostatic glandular cells: 844.8;Renal collecting duct intercalated cells: 499.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014697 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 17: Intestine - Digestion" "Cluster 6: Non-specific - Immune response" "Cluster 60: Prostate cancer - Unknown function" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 3 "Nucleoplasm, Vesicles" Cytosol "HPA014697: " "unprognostic (4.36e-3)" "unprognostic (1.36e-2)" "unprognostic (6.24e-2)" "unprognostic (6.78e-2)" "unprognostic (1.06e-1)" "unprognostic (2.69e-1)" "unprognostic (1.65e-2)" "unprognostic (2.39e-2)" "unprognostic (2.16e-2)" "unprognostic (2.17e-2)" "validated prognostic favorable (2.09e-5)" "validated prognostic favorable (1.46e-4)" "potential prognostic unfavorable (1.10e-5)" "unprognostic (4.24e-2)" "unprognostic (8.00e-2)" "potential prognostic favorable (4.40e-4)" "unprognostic (2.37e-2)" "unprognostic (1.99e-1)" "unprognostic (2.24e-1)" "unprognostic (5.14e-2)" "unprognostic (4.29e-3)" "unprognostic (4.06e-2)" "unprognostic (1.57e-1)" "unprognostic (4.30e-2)" "unprognostic (4.54e-2)" "unprognostic (8.41e-3)" "unprognostic (4.95e-2)" "unprognostic (2.19e-1)" "unprognostic (2.17e-1)" "unprognostic (1.33e-2)" "unprognostic (3.18e-2)" SLC22A24 "MGC34821, NET46" ENSG00000197658 "Solute carrier family 22 member 24" Q8N4F4 11 63079940-63144221 "Essential proteins, Predicted membrane proteins" "Ion transport, Lipid metabolism, Lipid transport, Steroid metabolism, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 10 "kidney: 4.1" "Cell type enriched" "Detected in some" 8 "Proximal tubule cells: 76.0" "Cell type enhanced" "Detected in many" "deep-layer corticothalamic and 6b: 29.8;deep-layer intratelencephalic: 23.2;upper-layer intratelencephalic: 51.0" "Cancer enhanced" "Detected in single" "Kidney Renal Papillary Cell Carcinoma (TCGA): 1.8" "Region enhanced" "Detected in many" "cerebral cortex: 6.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells" HPA045015 Uncertain NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 53: Neurons - Mixed function" "Cluster 88: Proximal tubular cells - Transmembrane transport" "HPA045015: " "unprognostic (2.20e-3)" "potential prognostic favorable (5.69e-6)" SLC22A25 "HIMTP, MGC120420, UST6" ENSG00000196600 "Solute carrier family 22 member 25" Q6T423 11 63158437-63243599 "Predicted membrane proteins, Transporters" Transport "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 13 "liver: 29.8" "Cell type enriched" "Detected in some" 4 "Hepatocytes: 120.4" "Cell type enhanced" "Detected in many" "deep-layer corticothalamic and 6b: 11.3;upper-layer intratelencephalic: 20.6" "Cancer enriched" "Detected in single" 14 "Liver Hepatocellular Carcinoma (TCGA): 1.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Liver - Hepatocytes" HPA039390 Uncertain NA NA "Cluster 53: Liver - Plasma proteins" "Cluster 9: Non-specific - Receptor signaling" "Cluster 50: Lymphoma - Unknown function" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" "HPA039390: " "unprognostic (4.01e-3)" "potential prognostic favorable (2.54e-6)" SLC22A3 "EMT, OCT3" ENSG00000146477 "Solute carrier family 22 member 3" O75751 6 160348378-160452577 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 77.1" "Cell type enhanced" "Detected in many" "Adipocytes: 106.3;Adrenal cortex cells: 162.2;Alveolar cells type 2: 250.6;Hepatocytes: 115.7;Leydig cells: 208.6;Myonuclei: 192.6;Oligodendrocyte progenitor cells: 135.2;Peritubular myoid cells: 125.5;Prostatic glandular cells: 647.1;Salivary acinar cells: 271.4;Smooth muscle cells: 151.6;Transitional alveolar cells: 244.3;Vascular smooth muscle cells: 185.1" "Cell type enhanced" "Detected in many" "oligodendrocyte precursor cell: 196.0;vascular associated smooth muscle cell: 313.0" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 28.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 27.8;prostate cancer: 30.0" "Adipose visceral - Adipocytes (Visceral), Heart muscle - Smooth muscle cells, Lung - Alveolar cells type 2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA029750 Approved Approved Vesicles,Cytosol NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 43: Hindbrain - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" Vesicles Cytosol "HPA029750: " "unprognostic (2.08e-1)" "potential prognostic favorable (1.41e-4)" "potential prognostic unfavorable (6.44e-5)" "unprognostic (3.46e-1)" "unprognostic (2.07e-2)" "unprognostic (1.27e-1)" "unprognostic (6.94e-2)" "unprognostic (3.27e-1)" "unprognostic (1.49e-1)" "unprognostic (6.51e-3)" "potential prognostic favorable (1.38e-4)" "unprognostic (7.63e-2)" "unprognostic (8.85e-2)" "unprognostic (7.36e-3)" "unprognostic (2.02e-1)" "potential prognostic unfavorable (6.87e-4)" "unprognostic (7.78e-2)" "unprognostic (1.10e-2)" "unprognostic (2.11e-2)" "unprognostic (1.46e-1)" "unprognostic (4.25e-2)" "unprognostic (3.24e-1)" "unprognostic (4.38e-2)" "unprognostic (1.14e-2)" "potential prognostic unfavorable (4.57e-4)" SLC22A31 ENSG00000259803 "Solute carrier family 22 member 31" A6NKX4 16 89195761-89201651 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 132.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 60.8;Alveolar cells type 2: 261.9;Brain excitatory neurons: 29.8;Early spermatids: 25.6;Late spermatids: 62.5;Pancreatic acinar cells: 24.9;Transitional alveolar cells: 143.5" "Cell type enriched" "Detected in some" 20 "upper rhombic lip: 59.8" "Group enriched" "Detected in many" 6 "Lung Adenocarcinoma (TCGA): 74.0;Thyroid Carcinoma (TCGA): 33.5" "Region enriched" "Detected in many" 10 "cerebellum: 63.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 11.7" "Kidney - Fibroblasts, Lung - Alveolar cells type 2, Skin - Sebaceous gland cells" NA NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 81: Alveolar cells - Lung function" "unprognostic (2.75e-3)" "unprognostic (2.00e-2)" "unprognostic (1.45e-3)" "unprognostic (9.07e-2)" "unprognostic (4.19e-3)" "unprognostic (7.48e-2)" "unprognostic (2.03e-1)" "unprognostic (1.56e-1)" "unprognostic (1.35e-1)" "unprognostic (2.61e-1)" "unprognostic (1.98e-1)" "unprognostic (5.29e-3)" "unprognostic (2.40e-2)" SLC22A4 "DFNB60, MGC34546, OCTN1" ENSG00000197208 "Solute carrier family 22 member 4" Q9H015 5 132294394-132344190 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Ion transport, Sodium transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 440.3;Epicardial cells: 279.7;Fallopian tube ciliated cells: 86.7;Myonuclei: 125.6;Neutrophils: 264.8;Respiratory ciliated cells: 200.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "neutrophil: 36.3" "Lineage enriched" "Detected in many" 6 "granulocytes: 36.3" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Spleen - Neutrophils_2" "Region enhanced" "Detected in all" "cerebellum: 64.5" "Low region specificity" "Detected in many" "CAB015468, HPA036974" Approved Supported Mitochondria NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 44: Non-specific - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 8 Mitochondria "CAB015468: , HPA036974: " "unprognostic (2.57e-1)" "unprognostic (3.05e-1)" "unprognostic (3.03e-1)" "unprognostic (1.02e-1)" "unprognostic (7.52e-2)" "unprognostic (1.33e-1)" "unprognostic (1.19e-1)" "unprognostic (2.65e-1)" "unprognostic (1.01e-2)" "validated prognostic favorable (5.56e-8)" "validated prognostic favorable (1.41e-5)" "unprognostic (1.16e-2)" "unprognostic (2.43e-2)" "unprognostic (1.67e-1)" "unprognostic (2.45e-1)" "unprognostic (1.79e-1)" "unprognostic (1.97e-1)" "unprognostic (1.18e-2)" "unprognostic (1.04e-1)" "unprognostic (4.15e-2)" "unprognostic (3.96e-3)" "unprognostic (1.27e-3)" "unprognostic (1.89e-1)" "potential prognostic favorable (6.47e-4)" "unprognostic (1.95e-1)" "unprognostic (9.30e-2)" "potential prognostic unfavorable (7.75e-4)" "unprognostic (2.07e-1)" "unprognostic (4.69e-2)" SLC22A5 "CDSP, OCTN2, SCD" ENSG00000197375 "Solute carrier family 22 member 5" O76082 5 132369710-132395613 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 33.7" "Cell type enriched" "Detected in many" 5 "Proximal tubule cells: 548.0" "Cell type enhanced" "Detected in all" "endothelial cell: 114.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Breast - Breast glandular cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA063062 Approved Mitochondria NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 7: Liver cancer - Metabolism" "Cluster 88: Proximal tubular cells - Transmembrane transport" 8 Mitochondria "HPA063062: " "unprognostic (1.56e-3)" "unprognostic (7.50e-2)" "unprognostic (9.67e-2)" "unprognostic (2.58e-1)" "unprognostic (4.00e-3)" "unprognostic (5.27e-2)" "unprognostic (3.32e-2)" "unprognostic (1.35e-2)" "unprognostic (1.64e-1)" "unprognostic (8.35e-2)" "potential prognostic favorable (3.39e-8)" "unprognostic (2.45e-3)" "potential prognostic favorable (5.27e-5)" "unprognostic (3.11e-3)" "unprognostic (2.57e-1)" "unprognostic (7.29e-2)" "unprognostic (1.01e-1)" "unprognostic (3.57e-1)" "unprognostic (1.92e-1)" "unprognostic (3.21e-1)" "unprognostic (3.62e-1)" "potential prognostic favorable (8.16e-4)" "unprognostic (2.44e-1)" "unprognostic (1.15e-1)" "unprognostic (9.56e-3)" "unprognostic (5.84e-2)" "unprognostic (3.31e-1)" "unprognostic (4.69e-2)" "unprognostic (2.79e-1)" "unprognostic (8.00e-2)" "unprognostic (2.02e-1)" SLC22A6 "OAT1, PAHT, ROAT1" ENSG00000197901 "Solute carrier family 22 member 6" Q4U2R8 11 62936385-62984967 "FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 32 "kidney: 183.7" "Cell type enriched" "Detected in some" 5 "Proximal tubule cells: 365.4" "Cell type enhanced" "Detected in many" "astrocyte: 31.6;fibroblast: 24.8;upper-layer intratelencephalic: 16.4" "Group enriched" "Detected in some" 120 "Kidney Renal Clear Cell Carcinoma (TCGA): 21.1;Kidney Renal Papillary Cell Carcinoma (TCGA): 54.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA074559, CAB075704" Enhanced NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 19: Astrocytes - Mixed function" "Cluster 88: Proximal tubular cells - Transmembrane transport" 2 "CAB075704: , HPA074559: " "validated prognostic favorable (1.68e-8)" "validated prognostic favorable (9.01e-6)" "unprognostic (1.18e-1)" SLC22A7 "NLT, OAT2" ENSG00000137204 "Solute carrier family 22 member 7" Q9Y694 6 43295694-43305538 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "liver: 419.3" "Group enriched" "Detected in some" 18 "Hepatocytes: 352.9;Proximal tubule cells: 117.9" "Low cell type specificity" "Detected in some" "Cancer enriched" "Detected in some" 18 "Liver Hepatocellular Carcinoma (TCGA): 164.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA030220 Approved NA NA "Cluster 53: Liver - Plasma proteins" "Cluster 15: Non-specific - Transcription" "Cluster 18: Liver cancer - Metabolism" "Cluster 88: Proximal tubular cells - Transmembrane transport" "HPA030220: " "potential prognostic favorable (1.98e-7)" "unprognostic (8.74e-2)" "unprognostic (9.64e-3)" "validated prognostic favorable (2.89e-6)" "validated prognostic favorable (5.53e-5)" SLC22A8 OAT3 ENSG00000149452 "Solute carrier family 22 member 8" Q8TCC7 11 62989154-63015841 "FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Detoxification, Ion transport, Lipid transport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 188 "choroid plexus: 266.1;kidney: 312.8" "Group enriched" "Detected in some" 15 "Choroid plexus epithelial cells: 148.1;Proximal tubule cells: 148.4;Retinal pigment epithelial cells: 464.7" "Cell type enriched" "Detected in many" 6 "choroid plexus epithelial cell: 119.6" "Cancer enhanced" "Detected in some" "Kidney Renal Clear Cell Carcinoma (TCGA): 3.0;Kidney Renal Papillary Cell Carcinoma (TCGA): 5.4" "Region enriched" "Detected in some" 31 "choroid plexus: 242.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA044174 Enhanced NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" "HPA044174: " "potential prognostic favorable (3.23e-9)" "unprognostic (1.28e-2)" "unprognostic (3.53e-2)" "unprognostic (1.63e-1)" SLC22A9 "FLJ23666, OAT4, OAT7, UST3" ENSG00000149742 "Solute carrier family 22 member 9" Q8IVM8 11 63369785-63410294 "Metabolic proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 29 "liver: 43.3" "Cell type enriched" "Detected in some" 4 "Hepatocytes: 32.8" "Cell type enhanced" "Detected in many" "amygdala excitatory: 17.4;deep-layer corticothalamic and 6b: 29.1;deep-layer intratelencephalic: 19.2;upper-layer intratelencephalic: 27.9" "Cancer enriched" "Detected in single" 35 "Liver Hepatocellular Carcinoma (TCGA): 23.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 16 "liver cancer: 3.9;Myeloma: 1.7" "Liver - Hepatocytes, Skin - Sebaceous gland cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 53: Neurons - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 35: Neurons - Synaptic function & neurogenesis" 23 "unprognostic (2.02e-1)" "unprognostic (3.98e-2)" SLC23A1 "SLC23A2, SVCT1, YSPL3" ENSG00000170482 "Solute carrier family 23 member 1" Q9UHI7 5 139367196-139384553 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "fallopian tube: 50.9;intestine: 61.5;kidney: 37.5;liver: 21.3" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 8.3;Endometrial ciliated cells: 33.5;Enterocytes: 25.6;Epicardial cells: 13.6;Fallopian tube ciliated cells: 42.8;Prostatic glandular cells: 11.5;Proximal tubule cells: 13.8;Respiratory ciliated cells: 9.6;Thymocytes: 8.5" "Cell type enhanced" "Detected in some" "ependymal cell: 3.5" "Group enriched" "Detected in many" 5 "Kidney Renal Clear Cell Carcinoma (TCGA): 8.1;Kidney Renal Papillary Cell Carcinoma (TCGA): 9.6;Liver Hepatocellular Carcinoma (TCGA): 13.2;Prostate Adenocarcinoma (TCGA): 10.9;Uterine Corpus Endometrial Carcinoma (TCGA): 4.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.3" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 4 "Leukemia: 9.2;lymphoma: 10.5;Myeloma: 20.5" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA047612 Enhanced NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 46: Brainstem - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 107: Ciliated cells - Cilia assembly & function" 12 "HPA047612: " "unprognostic (4.96e-2)" "unprognostic (1.81e-1)" "unprognostic (9.86e-2)" "unprognostic (3.74e-2)" "unprognostic (6.06e-3)" "unprognostic (3.50e-1)" "unprognostic (1.80e-1)" "unprognostic (1.97e-1)" "unprognostic (2.26e-2)" "unprognostic (5.26e-2)" "unprognostic (1.27e-2)" "unprognostic (3.40e-1)" "unprognostic (6.29e-2)" "unprognostic (1.09e-2)" "unprognostic (1.37e-1)" "unprognostic (7.36e-3)" "unprognostic (6.44e-2)" "unprognostic (1.59e-2)" SLC23A2 "KIAA0238, SLC23A1, SVCT2, YSPL2" ENSG00000089057 "Solute carrier family 23 member 2" Q9UGH3 20 4852356-5010293 "Metabolic proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 96.5;retina: 99.4" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 564.1;Choroid plexus epithelial cells: 667.0;Cone photoreceptor cells: 546.5;Retinal bipolar cells: 766.4;Retinal horizontal cells: 328.6;Retinal pigment epithelial cells: 750.3;Rod photoreceptor cells: 486.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052825, HPA059314" Approved Uncertain "Golgi apparatus,Vesicles" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 69: Skin cancer - ECM organization" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 2 Vesicles "Golgi apparatus" "HPA052825: , HPA059314: " "unprognostic (2.07e-1)" "unprognostic (1.93e-1)" "unprognostic (6.28e-2)" "unprognostic (1.13e-2)" "unprognostic (7.15e-3)" "unprognostic (1.05e-1)" "unprognostic (6.66e-2)" "unprognostic (1.51e-2)" "unprognostic (2.70e-1)" "unprognostic (9.89e-3)" "potential prognostic favorable (6.26e-4)" "unprognostic (1.25e-2)" "unprognostic (1.73e-1)" "unprognostic (1.08e-3)" "unprognostic (2.18e-3)" "unprognostic (1.26e-2)" "unprognostic (2.88e-1)" "unprognostic (3.52e-2)" "unprognostic (5.19e-2)" "unprognostic (2.56e-3)" "unprognostic (1.69e-1)" "unprognostic (3.69e-3)" "unprognostic (1.19e-1)" "unprognostic (2.37e-1)" "unprognostic (2.26e-1)" "unprognostic (1.93e-1)" "unprognostic (1.80e-1)" "unprognostic (1.54e-1)" "unprognostic (1.39e-1)" "unprognostic (5.40e-2)" "unprognostic (1.25e-1)" SLC23A3 "FLJ31168, SVCT3, Yspl1" ENSG00000213901 "Solute carrier family 23 member 3" Q6PIS1 2 219161465-219170095 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "intestine: 17.3;kidney: 42.6" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Kidney Renal Clear Cell Carcinoma (TCGA): 26.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Kidney - Proximal tubular cells" "Region enhanced" "Detected in single" "cerebral cortex: 1.3" "Not detected" "Not detected" HPA019059 Approved "Nucleoplasm,Cell Junctions" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 25: Non-specific - Transcription" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" Nucleoplasm "Cell Junctions" "HPA019059: " "unprognostic (6.25e-2)" "unprognostic (1.26e-3)" "unprognostic (3.47e-2)" "validated prognostic favorable (3.57e-6)" "validated prognostic favorable (9.29e-5)" "unprognostic (1.22e-2)" "unprognostic (1.12e-1)" "unprognostic (6.34e-2)" "unprognostic (2.01e-1)" "unprognostic (4.34e-2)" "unprognostic (2.21e-1)" "unprognostic (1.12e-3)" "unprognostic (2.86e-2)" SLC24A1 "CSNB1D, HsT17412, KIAA0702, NCKX, NCKX1, RODX" ENSG00000074621 "Solute carrier family 24 member 1" O60721 15 65611366-65660995 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Sensory transduction, Symport, Transport, Vision" "Congenital stationary night blindness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 34 "retina: 179.2" "Cell type enhanced" "Detected in many" "Epicardial cells: 134.2;Epididymal basal cells: 109.8;Lymphatic endothelial cells: 76.9;Retinal bipolar cells: 89.7;Rod photoreceptor cells: 439.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Endothelial cells, Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA039370 Enhanced NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 42: Retina - Visual perception" "Cluster 15: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 79: Photoreceptor cells - Phototransduction" "HPA039370: " "unprognostic (8.88e-2)" "unprognostic (1.09e-1)" "unprognostic (1.26e-1)" "potential prognostic unfavorable (4.38e-4)" "unprognostic (1.58e-1)" "unprognostic (1.72e-1)" "unprognostic (7.49e-2)" "unprognostic (8.75e-3)" "unprognostic (1.73e-2)" "unprognostic (1.66e-2)" "unprognostic (7.58e-3)" "unprognostic (3.71e-2)" "potential prognostic favorable (4.32e-6)" "unprognostic (8.29e-2)" "unprognostic (1.04e-1)" "unprognostic (2.75e-1)" "unprognostic (8.86e-2)" "unprognostic (1.82e-1)" "unprognostic (1.15e-2)" "unprognostic (1.55e-1)" "unprognostic (1.36e-1)" "unprognostic (1.01e-1)" "unprognostic (3.51e-2)" "unprognostic (1.14e-1)" "unprognostic (3.13e-1)" "unprognostic (1.77e-2)" "unprognostic (1.80e-2)" "unprognostic (2.30e-1)" "unprognostic (1.03e-1)" "unprognostic (1.80e-2)" "unprognostic (1.25e-2)" SLC24A2 NCKX2 ENSG00000155886 "Solute carrier family 24 member 2" Q9UI40 9 19507452-19789037 "Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Potassium transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 25.6;retina: 15.2" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 797.8;Brain excitatory neurons: 343.7;Brain inhibitory neurons: 567.3;Cone photoreceptor cells: 2155.0;Gonadotrophs: 481.2;Oligodendrocytes: 3412.9;Retinal amacrine cells: 396.9;Retinal bipolar cells: 304.2;Retinal horizontal cells: 811.4" "Cell type enhanced" "Detected in all" "oligodendrocyte: 4299.7" "Group enriched" "Detected in some" 5 "Breast Invasive Carcinoma (TCGA): 1.0;Glioblastoma Multiforme (TCGA): 2.6;Kidney Chromophobe (TCGA): 2.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Bone cancer: 1.0" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA079359 Supported "Plasma membrane" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 34: Non-specific - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 80: Oligodendrocytes - Myelination" "Plasma membrane" "HPA079359: " "unprognostic (7.47e-2)" "unprognostic (4.82e-2)" "unprognostic (1.74e-1)" "unprognostic (1.81e-1)" "unprognostic (1.97e-1)" "unprognostic (2.66e-1)" SLC24A3 ENSG00000185052 "Solute carrier family 24 member 3" Q9HC58 20 19212642-19722926 "Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Potassium transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bergmann glia: 424.2;Endometrial stromal cells: 841.5;Mast cells: 2522.0;Megakaryocyte progenitors: 956.1;Oligodendrocyte progenitor cells: 619.3" "Cell type enhanced" "Detected in all" "hippocampal CA4: 1388.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 38 "basophil: 5.7;eosinophil: 1.9" "Lineage enriched" "Detected in single" 58 "granulocytes: 5.7" "Group enriched" "Detected in some" 4 "Bile duct cancer: 6.2;Bone cancer: 13.7;breast cancer: 11.4" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Pituitary gland - Fibroblasts, Prostate - Smooth muscle cells, Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043400, HPA045497" Uncertain Uncertain "Golgi apparatus,Cytosol" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 29: Forebrain - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 58: Mast cells - Allergic inflammatory responses" 1 "Golgi apparatus" Cytosol "HPA043400: , HPA045497: " "potential prognostic favorable (3.74e-4)" "unprognostic (9.44e-2)" "unprognostic (6.29e-2)" "unprognostic (1.85e-2)" "unprognostic (4.01e-2)" "unprognostic (5.57e-2)" "unprognostic (1.24e-1)" "unprognostic (1.95e-3)" "unprognostic (3.39e-1)" "unprognostic (2.56e-1)" "unprognostic (1.63e-2)" "unprognostic (3.49e-2)" "unprognostic (2.70e-2)" "unprognostic (1.95e-1)" "validated prognostic unfavorable (8.78e-4)" "validated prognostic unfavorable (1.97e-4)" "unprognostic (3.82e-2)" "unprognostic (9.27e-2)" "unprognostic (8.56e-2)" "unprognostic (4.48e-3)" "unprognostic (1.08e-1)" "unprognostic (5.72e-2)" "unprognostic (1.04e-2)" "unprognostic (9.56e-2)" "unprognostic (3.39e-2)" "unprognostic (1.57e-1)" "potential prognostic unfavorable (5.08e-4)" "unprognostic (2.92e-1)" SLC24A4 NCKX4 ENSG00000140090 "Solute carrier family 24 member 4" Q8NFF2 14 92322581-92501481 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Olfaction, Potassium transport, Sensory transduction, Sodium transport, Symport, Transport" "Amelogenesis imperfecta, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "choroid plexus: 43.5;retina: 11.4" "Group enriched" "Detected in many" 8 "Choroid plexus epithelial cells: 1344.1;Cone photoreceptor cells: 519.6;Retinal bipolar cells: 631.4" "Cell type enriched" "Detected in many" 4 "choroid plexus epithelial cell: 1029.6" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 1.5;Skin Cutaneous Melanoma (TCGA): 2.3" "Region enhanced" "Detected in all" "choroid plexus: 200.5" "Group enriched" "Detected in some" 4 "classical monocyte: 11.1;intermediate monocyte: 14.7;non-classical monocyte: 11.6" "Lineage enriched" "Detected in many" 5 "monocytes: 14.7" "Group enriched" "Detected in some" 10 "Sarcoma: 4.4;skin cancer: 1.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063206 Approved "Plasma membrane" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 54: Non-specific - Transcription" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "Plasma membrane" "HPA063206: " "unprognostic (1.64e-2)" "unprognostic (1.37e-1)" "unprognostic (2.41e-2)" "unprognostic (7.84e-2)" SLC24A5 "JSX, OCA6" ENSG00000188467 "Solute carrier family 24 member 5" Q71RS6 15 48120990-48142672 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Potassium transport, Sensory transduction, Sodium transport, Symport, Transport" Albinism "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "skin 1: 7.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 41.5;Early spermatids: 62.2;Late spermatids: 66.4;Melanocytes: 199.0;Retinal amacrine cells: 36.1;Retinal bipolar cells: 24.1;Retinal ganglion cells: 30.9;Retinal horizontal cells: 44.1;Retinal pigment epithelial cells: 38.4" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in some" 18 "Skin Cutaneous Melanoma (TCGA): 101.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 63 "skin cancer: 98.8" "Skin - Melanocytes, Testis - Early spermatids, Testis - Late spermatids" "Group enriched" "Detected in some" 5 "hippocampal formation: 3.0;pons and medulla: 4.1;thalamus: 1.5" "Low region specificity" "Detected in all" NA NA "Cluster 37: Skin - Keratinization" "Cluster 19: Astrocytes - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 61: Schwann cells & Melanocytes - Mixed function" 2 "unprognostic (1.21e-1)" "unprognostic (5.63e-2)" "unprognostic (3.90e-2)" "unprognostic (4.84e-1)" "unprognostic (1.34e-1)" SLC25A1 "CTP, SLC20A3" ENSG00000100075 "Solute carrier family 25 member 1" P53007 22 19175581-19178739 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Antiport, Transport" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 206.9" "Cell type enhanced" "Detected in many" "Colonocytes: 142.9;Cytotrophoblasts: 164.0;Enterocytes: 272.5;Extravillous trophoblasts: 158.2;Hepatocytes: 208.3;Late spermatids: 183.5;Syncytiotrophoblasts: 138.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 102.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Liver - Hepatocytes, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 31000 "Cluster 45: Eosinophils - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 66: Non-specific - Mitochondria" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 15 "unprognostic (7.98e-2)" "unprognostic (2.31e-2)" "unprognostic (1.49e-1)" "unprognostic (1.46e-3)" "unprognostic (2.02e-2)" "unprognostic (2.76e-2)" "unprognostic (1.48e-2)" "unprognostic (1.12e-2)" "unprognostic (2.36e-2)" "unprognostic (4.12e-2)" "unprognostic (1.70e-1)" "unprognostic (4.88e-2)" "unprognostic (2.41e-1)" "unprognostic (5.59e-3)" "unprognostic (8.62e-2)" "unprognostic (2.19e-3)" "unprognostic (8.31e-2)" "unprognostic (6.59e-2)" "unprognostic (1.55e-1)" "unprognostic (1.96e-1)" "unprognostic (3.74e-3)" "unprognostic (2.55e-1)" "unprognostic (1.09e-1)" "unprognostic (1.97e-1)" "unprognostic (1.19e-1)" "unprognostic (3.36e-1)" "unprognostic (1.76e-1)" "unprognostic (2.83e-1)" "unprognostic (9.54e-2)" "unprognostic (9.93e-3)" "unprognostic (1.08e-1)" SLC25A10 DIC ENSG00000183048 "Solute carrier family 25 member 10" Q9UBX3 17 81712236-81721016 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Lipid transport, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 179.7" "Cell type enhanced" "Detected in many" "Colonocytes: 48.2;Enteric stem cells: 43.2;Enteric transient amplifying cells: 58.0;Enterocytes: 40.8;Esophageal basal cells: 68.5;Esophageal suprabasal cells: 52.7;Hepatocytes: 47.0;Late primary spermatocytes: 81.3;Late spermatids: 141.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Spleen - Mitotic cells (Spleen), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023048 Supported Supported Nucleoplasm,Mitochondria NA NA "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 19: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 16 Mitochondria Nucleoplasm "HPA023048: " "unprognostic (6.53e-2)" "unprognostic (1.89e-1)" "unprognostic (1.91e-1)" "unprognostic (1.01e-1)" "unprognostic (1.44e-2)" "unprognostic (5.56e-3)" "unprognostic (5.70e-3)" "unprognostic (1.68e-2)" "potential prognostic favorable (7.69e-4)" "potential prognostic unfavorable (9.55e-4)" "unprognostic (4.67e-2)" "unprognostic (5.22e-2)" "unprognostic (8.83e-2)" "unprognostic (7.77e-2)" "unprognostic (2.23e-1)" "unprognostic (1.54e-1)" "unprognostic (6.11e-3)" "unprognostic (2.87e-1)" "unprognostic (3.08e-2)" "unprognostic (9.57e-3)" "unprognostic (1.82e-2)" "unprognostic (2.61e-2)" "unprognostic (6.43e-2)" "unprognostic (1.21e-1)" "unprognostic (8.29e-3)" "unprognostic (2.08e-1)" "unprognostic (7.18e-3)" "unprognostic (1.68e-1)" "unprognostic (2.66e-1)" "unprognostic (7.20e-3)" "unprognostic (1.72e-1)" SLC25A11 "OGC, SLC20A4" ENSG00000108528 "Solute carrier family 25 member 11" Q02978 17 4937130-4940053 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Lipid transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "heart muscle: 218.8;skeletal muscle: 294.7;tongue: 419.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 155.1;Extravillous trophoblasts: 167.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021167 Approved NA NA 5600 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 52: Non-specific - Cellular respiration" "Cluster 45: Non-specific - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 30 "HPA021167: " "unprognostic (2.49e-2)" "unprognostic (3.94e-3)" "potential prognostic unfavorable (7.15e-4)" "unprognostic (1.88e-2)" "unprognostic (1.27e-1)" "unprognostic (2.52e-1)" "unprognostic (1.95e-1)" "unprognostic (2.15e-1)" "unprognostic (1.94e-1)" "unprognostic (1.06e-2)" "potential prognostic favorable (7.26e-9)" "unprognostic (3.23e-2)" "potential prognostic favorable (5.47e-7)" "unprognostic (2.74e-1)" "unprognostic (6.83e-2)" "unprognostic (1.11e-1)" "unprognostic (2.80e-1)" "unprognostic (4.00e-1)" "unprognostic (2.73e-1)" "unprognostic (1.59e-1)" "unprognostic (2.50e-1)" "potential prognostic favorable (1.44e-4)" "unprognostic (8.43e-2)" "unprognostic (5.08e-1)" "unprognostic (1.96e-1)" "unprognostic (5.65e-2)" "unprognostic (4.96e-2)" "unprognostic (1.67e-1)" "unprognostic (2.85e-1)" "unprognostic (1.17e-2)" "unprognostic (1.03e-2)" SLC25A12 Aralar ENSG00000115840 "Solute carrier family 25 member 12" O75746 2 171783405-171999859 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 44.6;tongue: 47.7" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 305.3;Choroid plexus epithelial cells: 331.8;Myonuclei: 702.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035333, HPA035334" Enhanced Uncertain "Nuclear speckles,Cytosol" NA NA 4800 "Cluster 24: Non-specific - Transcription" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 23 "Nuclear speckles" Cytosol "HPA035333: , HPA035334: " "unprognostic (3.29e-2)" "unprognostic (4.86e-2)" "unprognostic (1.47e-2)" "unprognostic (1.60e-2)" "unprognostic (2.22e-1)" "unprognostic (2.05e-2)" "unprognostic (8.50e-2)" "unprognostic (1.01e-2)" "unprognostic (2.94e-1)" "unprognostic (1.14e-1)" "unprognostic (1.47e-3)" "unprognostic (1.55e-3)" "unprognostic (4.65e-3)" "potential prognostic favorable (5.90e-4)" "unprognostic (6.76e-2)" "unprognostic (4.46e-2)" "unprognostic (2.28e-1)" "unprognostic (1.01e-1)" "unprognostic (1.89e-2)" "unprognostic (3.37e-1)" "unprognostic (2.86e-3)" "unprognostic (4.27e-3)" "unprognostic (3.28e-2)" "unprognostic (5.16e-2)" "unprognostic (9.08e-2)" "unprognostic (1.06e-1)" "unprognostic (1.13e-1)" "unprognostic (2.78e-1)" "unprognostic (2.19e-2)" "unprognostic (6.82e-2)" SLC25A13 "ARALAR2, CITRIN, CTLN2" ENSG00000004864 "Solute carrier family 25 member 13" Q9UJS0 7 96120220-96322147 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" Transport "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 140.4" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 434.3;Neutrophils: 469.9;Oligodendrocytes: 485.3" "Cell type enhanced" "Detected in all" "oligodendrocyte: 759.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018997 Enhanced Supported Mitochondria NA NA 10000 "Cluster 25: Non-specific - Unknown function" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 31 Mitochondria "HPA018997: " "unprognostic (2.02e-1)" "unprognostic (6.02e-3)" "unprognostic (8.70e-2)" "unprognostic (1.37e-3)" "unprognostic (1.75e-1)" "unprognostic (1.30e-2)" "unprognostic (3.10e-1)" "unprognostic (1.09e-1)" "unprognostic (1.84e-1)" "unprognostic (2.96e-3)" "potential prognostic favorable (4.28e-8)" "unprognostic (5.59e-2)" "unprognostic (7.03e-2)" "unprognostic (3.20e-3)" "unprognostic (1.33e-1)" "unprognostic (5.23e-2)" "unprognostic (7.13e-3)" "unprognostic (1.14e-1)" "unprognostic (2.46e-1)" "unprognostic (2.83e-2)" "unprognostic (1.51e-1)" "unprognostic (6.41e-2)" "unprognostic (1.31e-1)" "unprognostic (8.47e-2)" "unprognostic (1.14e-1)" "unprognostic (7.64e-2)" "unprognostic (3.21e-2)" "unprognostic (5.86e-2)" "unprognostic (4.72e-1)" "unprognostic (2.36e-1)" "unprognostic (9.82e-2)" SLC25A14 "BMCP1, UCP5" ENSG00000102078 "Solute carrier family 25 member 14" O95258 X 130339888-130373361 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 46.5;Respiratory ciliated cells: 44.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060316 Approved Mitochondria NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 14: Neurons - Synaptic function" "Cluster 36: Non-specific - mRNA processing" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 1 Mitochondria "HPA060316: " "unprognostic (1.28e-1)" "potential prognostic unfavorable (2.06e-4)" "unprognostic (2.21e-1)" "unprognostic (6.68e-3)" "unprognostic (1.12e-1)" "unprognostic (9.49e-2)" "unprognostic (1.92e-1)" "unprognostic (2.34e-2)" "unprognostic (1.16e-1)" "unprognostic (1.79e-1)" "potential prognostic favorable (2.86e-8)" "unprognostic (2.80e-1)" "unprognostic (3.12e-1)" "unprognostic (3.70e-3)" "unprognostic (5.43e-2)" "unprognostic (3.38e-2)" "unprognostic (2.92e-2)" "unprognostic (2.45e-1)" "unprognostic (1.24e-1)" "unprognostic (2.78e-2)" "unprognostic (3.20e-2)" "unprognostic (6.37e-3)" "unprognostic (1.65e-1)" "unprognostic (3.20e-2)" "unprognostic (1.36e-1)" "unprognostic (3.76e-1)" "unprognostic (1.29e-1)" "unprognostic (9.91e-2)" "unprognostic (1.42e-1)" "unprognostic (6.76e-2)" "unprognostic (2.78e-1)" SLC25A15 "D13S327, HHH, ORC1, ORNT1" ENSG00000102743 "Solute carrier family 25 member 15" Q9Y619 13 40789412-40812460 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 35.4;liver: 99.4;pancreas: 48.9" "Cell type enhanced" "Detected in many" "Enterocytes: 72.2;Erythrocyte progenitors: 37.1;Extravillous trophoblasts: 154.2;Hepatocytes: 206.9;Megakaryocytes: 55.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA042146 Approved NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 20 "HPA042146: " "unprognostic (7.49e-2)" "unprognostic (3.84e-1)" "unprognostic (4.02e-1)" "potential prognostic unfavorable (2.36e-5)" "unprognostic (2.09e-1)" "unprognostic (8.52e-3)" "unprognostic (1.30e-1)" "unprognostic (2.47e-1)" "unprognostic (2.76e-1)" "unprognostic (1.17e-2)" "unprognostic (9.26e-3)" "unprognostic (9.95e-2)" "unprognostic (3.20e-3)" "potential prognostic favorable (7.42e-6)" "unprognostic (5.34e-3)" "unprognostic (2.54e-1)" "unprognostic (2.83e-3)" "unprognostic (1.73e-1)" "unprognostic (3.35e-2)" "unprognostic (1.49e-1)" "unprognostic (2.66e-2)" "unprognostic (6.68e-2)" "unprognostic (8.32e-3)" "unprognostic (1.08e-1)" "unprognostic (4.00e-2)" "unprognostic (1.60e-1)" "unprognostic (4.39e-2)" "unprognostic (2.01e-2)" "unprognostic (5.63e-2)" "unprognostic (2.58e-2)" "unprognostic (4.51e-2)" SLC25A16 "D10S105E, GDA, HGT.1, ML7" ENSG00000122912 "Solute carrier family 25 member 16" P16260 10 68477998-68527523 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 212.3;Retinal ganglion cells: 185.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 24.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036243, HPA044580" Uncertain Approved Mitochondria NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 34: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 89: Adipocytes - Lipid metabolism" 2 Mitochondria "HPA036243: , HPA044580: " "unprognostic (1.95e-2)" "unprognostic (4.44e-3)" "unprognostic (2.13e-1)" "unprognostic (2.67e-2)" "unprognostic (1.98e-2)" "unprognostic (2.84e-1)" "unprognostic (1.68e-1)" "potential prognostic favorable (1.36e-4)" "unprognostic (1.13e-1)" "unprognostic (2.65e-2)" "unprognostic (1.51e-1)" "unprognostic (8.26e-3)" "unprognostic (1.16e-3)" "unprognostic (8.86e-2)" "unprognostic (1.25e-1)" "unprognostic (2.50e-2)" "unprognostic (1.83e-1)" "unprognostic (8.29e-2)" "unprognostic (2.46e-1)" "unprognostic (4.04e-2)" "unprognostic (3.22e-1)" "unprognostic (3.93e-2)" "unprognostic (1.30e-2)" "unprognostic (2.42e-1)" "unprognostic (1.15e-1)" "unprognostic (1.82e-1)" "unprognostic (3.90e-2)" "unprognostic (3.43e-2)" "unprognostic (2.19e-1)" "unprognostic (4.38e-2)" "unprognostic (1.76e-2)" SLC25A17 PMP34 ENSG00000100372 "Solute carrier family 25 member 17" O43808 22 40769630-40819399 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Antiport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Corticotropes, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052708, HPA060972" Approved Supported Peroxisomes NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 75: Ovary - Mixed function" "Cluster 55: Non-specific - Transcription" "Cluster 66: Non-specific - Mitochondria" "Cluster 94: Gonadal somatic cells - Mixed function" 7 Peroxisomes "HPA052708: , HPA060972: " "unprognostic (1.83e-1)" "unprognostic (1.23e-1)" "unprognostic (3.10e-2)" "unprognostic (2.46e-2)" "unprognostic (3.77e-2)" "unprognostic (1.87e-1)" "unprognostic (7.19e-2)" "unprognostic (2.96e-1)" "unprognostic (5.50e-3)" "unprognostic (1.86e-1)" "potential prognostic favorable (2.40e-4)" "unprognostic (1.01e-2)" "unprognostic (2.53e-1)" "potential prognostic unfavorable (3.02e-4)" "unprognostic (3.86e-2)" "unprognostic (1.60e-2)" "unprognostic (3.54e-1)" "unprognostic (1.18e-2)" "unprognostic (1.04e-2)" "unprognostic (2.74e-3)" "unprognostic (2.19e-1)" "unprognostic (2.77e-1)" "unprognostic (1.93e-1)" "unprognostic (3.65e-1)" "unprognostic (1.66e-1)" "unprognostic (2.12e-1)" "unprognostic (8.68e-2)" "unprognostic (2.83e-2)" "unprognostic (1.48e-1)" "unprognostic (6.53e-2)" "unprognostic (3.22e-1)" SLC25A18 ENSG00000182902 "Solute carrier family 25 member 18" Q9H1K4 22 17563450-17590995 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 139.0;liver: 106.7" "Group enriched" "Detected in many" 4 "Astrocytes: 345.2;Bergmann glia: 99.3;Hepatocytes: 123.5" "Cell type enriched" "Detected in many" 4 "astrocyte: 421.4" "Group enriched" "Detected in many" 4 "Glioblastoma Multiforme (TCGA): 35.2;Liver Hepatocellular Carcinoma (TCGA): 26.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Prostate - Prostate glandular cells, Spleen - Fibroblasts_2, Testis - Sertoli cells" "Low region specificity" "Detected in all" HPA068110 Approved Nucleoplasm,Mitochondria NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 27: Breast cancer - Unknown function" "Cluster 28: Astrocytes - Homeostasis & neuron support" 7 Mitochondria Nucleoplasm "HPA068110: " "unprognostic (5.20e-2)" "unprognostic (6.95e-2)" "unprognostic (8.60e-2)" "unprognostic (1.87e-1)" "unprognostic (1.51e-1)" "unprognostic (3.72e-2)" "unprognostic (3.92e-3)" "unprognostic (7.68e-3)" "unprognostic (1.54e-1)" "unprognostic (6.95e-2)" "unprognostic (2.33e-3)" "unprognostic (2.38e-1)" "unprognostic (2.51e-1)" SLC25A19 "DNC, MCPHA, MUP1, TPC" ENSG00000125454 "Solute carrier family 25 member 19" Q9HC21 17 75272981-75289510 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Transport" "Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "cDC: 87.9;Extravillous trophoblasts: 115.9;Hofbauer cells: 42.9;Late primary spermatocytes: 171.0;monocytes: 48.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021936 Supported Mitochondria NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 39: Testis - Nuclear processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 28 Mitochondria "HPA021936: " "unprognostic (7.12e-2)" "unprognostic (1.58e-1)" "unprognostic (2.22e-2)" "unprognostic (3.30e-2)" "unprognostic (3.53e-1)" "unprognostic (8.12e-2)" "unprognostic (4.22e-2)" "unprognostic (6.22e-2)" "unprognostic (1.70e-1)" "potential prognostic unfavorable (3.77e-5)" "potential prognostic unfavorable (9.37e-6)" "unprognostic (5.26e-2)" "unprognostic (2.22e-1)" "validated prognostic unfavorable (1.53e-6)" "validated prognostic unfavorable (2.62e-6)" "unprognostic (1.72e-2)" "unprognostic (5.99e-3)" "unprognostic (1.46e-1)" "unprognostic (7.67e-2)" "unprognostic (1.79e-1)" "unprognostic (2.56e-3)" "unprognostic (1.68e-1)" "unprognostic (1.10e-2)" "unprognostic (3.44e-2)" "unprognostic (1.54e-1)" "unprognostic (8.28e-3)" "unprognostic (1.22e-1)" "unprognostic (4.06e-2)" "unprognostic (8.26e-2)" "unprognostic (1.17e-1)" "unprognostic (6.15e-3)" SLC25A2 ORNT2 ENSG00000120329 "Solute carrier family 25 member 2" Q9BXI2 5 141302635-141304049 "Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 24 "testis: 6.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" HPA042146 Uncertain NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 53: Neurons - Mixed function" 2 "HPA042146: " "unprognostic (9.67e-2)" SLC25A20 "CAC, CACT" ENSG00000178537 "Solute carrier family 25 member 20" O43772 3 48856926-48898904 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 138.7" "Cell type enhanced" "Detected in many" "Enterocytes: 73.7;Hepatocytes: 92.2;Myonuclei: 94.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Myeloma: 64.4" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016862, HPA029863" Approved Approved Mitochondria,Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 19: Astrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 55: Myocytes - Oxidative muscle function" "Mitochondria, Cytosol" "HPA016862: , HPA029863: " "unprognostic (2.09e-1)" "unprognostic (4.42e-2)" "unprognostic (4.46e-1)" "unprognostic (1.32e-1)" "unprognostic (1.68e-1)" "unprognostic (2.22e-1)" "unprognostic (3.00e-2)" "potential prognostic unfavorable (3.01e-6)" "unprognostic (9.79e-2)" "unprognostic (2.27e-2)" "potential prognostic favorable (6.12e-5)" "unprognostic (1.55e-2)" "unprognostic (3.69e-3)" "unprognostic (1.61e-1)" "unprognostic (1.16e-1)" "unprognostic (3.69e-2)" "unprognostic (2.68e-1)" "unprognostic (2.15e-1)" "unprognostic (2.55e-1)" "unprognostic (1.12e-1)" "unprognostic (5.16e-2)" "unprognostic (2.37e-2)" "unprognostic (6.35e-3)" "unprognostic (3.08e-1)" "unprognostic (1.83e-1)" "unprognostic (1.28e-1)" "unprognostic (1.31e-1)" "unprognostic (1.48e-1)" "unprognostic (1.52e-1)" "unprognostic (2.30e-2)" "unprognostic (1.11e-1)" SLC25A21 "ODC, ODC1" ENSG00000183032 "Solute carrier family 25 member 21" Q9BQT8 14 36677921-37172606 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Antiport, Lipid transport, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 5.9" "Group enriched" "Detected in many" 7 "Erythrocyte progenitors: 986.8;Sertoli cells: 1023.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 11.7" "Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA000662 Uncertain NA NA "Cluster 44: Bone marrow - Nuclear processes" "Cluster 27: Non-specific - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 1 "HPA000662: " "unprognostic (2.29e-2)" "unprognostic (1.56e-2)" "unprognostic (1.17e-1)" "unprognostic (1.33e-2)" "potential prognostic favorable (7.03e-4)" "unprognostic (2.49e-1)" "potential prognostic favorable (7.94e-6)" "unprognostic (2.49e-3)" "unprognostic (1.14e-1)" "unprognostic (5.14e-2)" "unprognostic (6.33e-2)" "unprognostic (1.76e-2)" "unprognostic (2.33e-1)" "unprognostic (2.27e-2)" "unprognostic (3.96e-1)" "unprognostic (9.65e-2)" "unprognostic (1.45e-1)" "unprognostic (1.09e-1)" SLC25A22 "EIEE3, FLJ13044, GC-1, GC1, NET44" ENSG00000177542 "Solute carrier family 25 member 22" Q9H936 11 790475-798281 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Symport, Transport" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 120.1;pancreas: 82.1" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 37.3;Oocytes: 50.7;Retinal bipolar cells: 101.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014662 Approved Uncertain Nucleoplasm,Mitochondria NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 27: Cerebellum - Synaptic function" "Cluster 51: Neurons - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 17 Mitochondria Nucleoplasm "HPA014662: " "unprognostic (1.96e-1)" "unprognostic (5.75e-2)" "unprognostic (2.52e-2)" "unprognostic (3.56e-2)" "unprognostic (3.88e-2)" "unprognostic (1.95e-1)" "unprognostic (3.43e-3)" "unprognostic (5.37e-2)" "unprognostic (1.02e-1)" "unprognostic (3.02e-2)" "unprognostic (2.31e-3)" "potential prognostic unfavorable (3.83e-4)" "unprognostic (2.76e-1)" "potential prognostic unfavorable (8.36e-4)" "unprognostic (9.59e-2)" "unprognostic (1.78e-3)" "potential prognostic unfavorable (7.53e-5)" "unprognostic (2.37e-2)" "unprognostic (6.99e-3)" "unprognostic (1.44e-1)" "unprognostic (1.12e-1)" "unprognostic (1.42e-1)" "unprognostic (3.54e-3)" "unprognostic (7.83e-2)" "unprognostic (4.70e-1)" "unprognostic (2.11e-1)" "unprognostic (2.54e-1)" "unprognostic (1.47e-2)" "unprognostic (7.51e-2)" "unprognostic (1.41e-3)" "unprognostic (1.09e-1)" SLC25A23 "APC2, FLJ30339, MGC2615" ENSG00000125648 "Solute carrier family 25 member 23" Q9BV35 19 6436079-6465203 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 364.2" "Cell type enhanced" "Detected in many" "Colonocytes: 148.3;Enterocytes: 116.5;Esophageal apical cells: 144.3;Late spermatids: 104.3;Ocular epithelial cells: 94.0;Salivary duct cells: 94.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal cortex cells, Colon - Smooth muscle cells, Prostate - Smooth muscle cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009675, HPA050883" Approved Supported Mitochondria NA NA "Cluster 24: Non-specific - Transcription" "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 5 Mitochondria "HPA009675: , HPA050883: " "potential prognostic favorable (3.78e-5)" "unprognostic (6.97e-2)" "unprognostic (1.82e-1)" "unprognostic (3.47e-2)" "unprognostic (1.05e-1)" "unprognostic (8.62e-2)" "unprognostic (3.88e-2)" "unprognostic (1.02e-1)" "unprognostic (1.66e-3)" "unprognostic (5.49e-2)" "potential prognostic favorable (1.39e-9)" "unprognostic (5.19e-2)" "potential prognostic favorable (6.40e-4)" "unprognostic (2.27e-2)" "unprognostic (9.46e-2)" "unprognostic (5.58e-2)" "unprognostic (4.11e-2)" "unprognostic (1.52e-2)" "unprognostic (2.25e-3)" "unprognostic (2.32e-1)" "unprognostic (5.84e-2)" "unprognostic (1.51e-1)" "unprognostic (2.69e-1)" "unprognostic (2.14e-1)" "unprognostic (5.55e-2)" "unprognostic (1.11e-1)" "unprognostic (5.23e-2)" "unprognostic (8.28e-2)" "unprognostic (1.41e-1)" "unprognostic (1.07e-1)" "unprognostic (8.77e-3)" SLC25A24 "APC1, DKFZp586G0123" ENSG00000085491 "Solute carrier family 25 member 24" Q6NUK1 1 108134043-108200849 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Podocytes: 64.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA028519, HPA063636" Enhanced Enhanced Mitochondria NA NA 5100 "Cluster 77: Intestine - Digestion" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 37: Non-specific - mRNA processing" "Cluster 102: Non-specific - Mixed function" 2 Mitochondria "HPA028519: , HPA063636: " "unprognostic (4.13e-2)" "unprognostic (4.26e-1)" "unprognostic (4.42e-2)" "unprognostic (7.72e-2)" "unprognostic (2.64e-3)" "unprognostic (6.69e-2)" "unprognostic (3.54e-2)" "potential prognostic unfavorable (8.93e-7)" "unprognostic (1.09e-1)" "unprognostic (8.25e-2)" "potential prognostic favorable (6.81e-8)" "unprognostic (5.52e-3)" "unprognostic (6.56e-2)" "unprognostic (4.28e-3)" "unprognostic (3.54e-2)" "unprognostic (2.84e-2)" "unprognostic (1.56e-1)" "unprognostic (3.56e-2)" "unprognostic (2.72e-1)" "unprognostic (2.95e-2)" "potential prognostic unfavorable (2.86e-4)" "unprognostic (2.95e-1)" "unprognostic (6.79e-2)" "unprognostic (4.47e-2)" "unprognostic (9.52e-2)" "unprognostic (6.61e-2)" "unprognostic (8.53e-2)" "unprognostic (1.06e-1)" "unprognostic (9.43e-2)" "unprognostic (1.73e-1)" SLC25A25 "KIAA1896, MCSC, PCSCL" ENSG00000148339 "Solute carrier family 25 member 25" Q6KCM7 9 128068201-128109245 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 108.5" "Cell type enhanced" "Detected in many" "Endometrial luminal cells: 287.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020381 Uncertain Supported Vesicles,Mitochondria NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 70: Non-specific - Protein processing" "Cluster 1: Neurons - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 5 "Vesicles, Mitochondria" "HPA020381: " "unprognostic (5.27e-2)" "unprognostic (3.50e-2)" "unprognostic (4.14e-2)" "unprognostic (1.32e-1)" "unprognostic (6.54e-2)" "unprognostic (1.87e-1)" "unprognostic (2.43e-1)" "unprognostic (3.31e-3)" "unprognostic (2.10e-1)" "unprognostic (1.04e-1)" "potential prognostic favorable (6.06e-4)" "unprognostic (3.82e-2)" "unprognostic (3.22e-2)" "potential prognostic favorable (1.49e-4)" "unprognostic (3.31e-3)" "unprognostic (1.88e-1)" "unprognostic (5.56e-2)" "unprognostic (3.04e-2)" "unprognostic (2.48e-3)" "unprognostic (2.07e-2)" "unprognostic (5.03e-2)" "unprognostic (3.93e-2)" "unprognostic (3.31e-1)" "unprognostic (1.12e-1)" "unprognostic (1.61e-1)" "unprognostic (2.48e-2)" "unprognostic (1.91e-1)" "unprognostic (5.60e-2)" "unprognostic (1.90e-1)" "potential prognostic unfavorable (4.65e-4)" "unprognostic (1.59e-1)" SLC25A26 ENSG00000144741 "Solute carrier family 25 member 26" Q70HW3 3 66133610-66388116 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 50.2;Bergmann glia: 58.1;Brain excitatory neurons: 70.7;Brain inhibitory neurons: 62.2;Choroid plexus epithelial cells: 71.2;Distal convoluted tubule cells: 82.5;Loop of henle epithelial cells: 72.7;Microglia: 87.0;Oligodendrocyte progenitor cells: 60.0;Oligodendrocytes: 87.2;Other brain neurons: 56.1;Papillary tip epithelial cells: 54.9;Podocytes: 68.7;Proximal tubule cells: 77.1;Renal collecting duct intercalated cells: 68.4;Renal collecting duct principal cells: 63.3;Renal connecting tubule cells: 79.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026887 Supported Supported Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 102: Non-specific - Mixed function" Mitochondria "HPA026887: " "unprognostic (4.48e-2)" "unprognostic (4.15e-1)" "unprognostic (4.68e-3)" "unprognostic (1.60e-1)" "unprognostic (1.14e-1)" "unprognostic (2.89e-1)" "unprognostic (3.35e-1)" "unprognostic (9.13e-2)" "unprognostic (5.11e-2)" "unprognostic (4.46e-2)" "potential prognostic favorable (4.02e-7)" "unprognostic (1.86e-2)" "unprognostic (2.61e-2)" "unprognostic (1.46e-2)" "potential prognostic unfavorable (8.12e-4)" "unprognostic (1.49e-1)" "unprognostic (8.35e-3)" "unprognostic (1.79e-1)" "unprognostic (3.72e-1)" "unprognostic (2.16e-1)" "unprognostic (8.83e-2)" "unprognostic (4.42e-2)" "unprognostic (1.36e-1)" "unprognostic (2.47e-1)" "unprognostic (1.43e-2)" "unprognostic (3.25e-2)" "unprognostic (1.68e-2)" "unprognostic (1.12e-1)" "unprognostic (2.00e-1)" "unprognostic (2.58e-1)" "unprognostic (1.95e-1)" SLC25A27 "FLJ33552, UCP4" ENSG00000153291 "Solute carrier family 25 member 27" O95847 6 46652915-46678190 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 162.7;Oligodendrocyte progenitor cells: 167.4;Thyrotrophs: 313.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069732 Supported Mitochondria NA NA "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 11: Neuronal - Sensory perception" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" Mitochondria "HPA069732: " "unprognostic (2.74e-2)" "unprognostic (2.44e-2)" "unprognostic (3.96e-2)" "unprognostic (2.23e-1)" "unprognostic (1.10e-1)" "unprognostic (1.58e-1)" "unprognostic (5.00e-2)" "unprognostic (1.83e-3)" "unprognostic (2.34e-1)" "unprognostic (4.07e-2)" "unprognostic (3.69e-2)" "potential prognostic favorable (3.92e-4)" "unprognostic (9.19e-3)" "unprognostic (1.91e-2)" "unprognostic (2.51e-1)" "unprognostic (1.31e-3)" "unprognostic (3.67e-2)" "unprognostic (3.12e-2)" "unprognostic (4.66e-2)" "unprognostic (4.06e-2)" "unprognostic (3.32e-2)" "unprognostic (1.84e-3)" "unprognostic (1.02e-2)" "unprognostic (2.65e-3)" "unprognostic (2.78e-3)" "unprognostic (4.05e-2)" "unprognostic (3.84e-2)" "unprognostic (1.55e-1)" "unprognostic (1.44e-1)" "unprognostic (2.69e-1)" "unprognostic (1.41e-2)" SLC25A28 "MRS3/4, MRS4L" ENSG00000155287 "Solute carrier family 25 member 28" Q96A46 10 99610519-99622793 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Iron transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 137.9;Late primary spermatocytes: 178.6;Late spermatids: 686.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Neutrophils, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" "unprognostic (5.69e-2)" "unprognostic (1.83e-1)" "unprognostic (9.00e-2)" "unprognostic (4.03e-3)" "unprognostic (2.26e-2)" "unprognostic (2.08e-1)" "unprognostic (1.24e-1)" "potential prognostic favorable (7.37e-4)" "unprognostic (3.79e-2)" "unprognostic (3.38e-1)" "unprognostic (1.84e-2)" "unprognostic (7.87e-2)" "unprognostic (2.11e-2)" "unprognostic (5.69e-2)" "unprognostic (2.64e-3)" "unprognostic (2.61e-1)" "unprognostic (2.44e-1)" "unprognostic (5.93e-2)" "unprognostic (2.33e-2)" "unprognostic (6.75e-2)" "unprognostic (5.92e-3)" "unprognostic (4.83e-2)" "unprognostic (1.19e-2)" "unprognostic (4.28e-2)" "unprognostic (2.74e-1)" "unprognostic (2.68e-2)" "unprognostic (1.88e-1)" "unprognostic (2.30e-1)" "unprognostic (1.68e-1)" "unprognostic (8.43e-2)" "unprognostic (2.58e-1)" SLC25A29 "C14orf69, FLJ38975" ENSG00000197119 "Solute carrier family 25 member 29" Q8N8R3 14 100291116-100306547 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 407.2" "Cell type enhanced" "Detected in many" "Breast lactating cells: 192.4;Endometrial glandular cells: 145.8;Renal collecting duct intercalated cells: 134.5;Renal collecting duct principal cells: 283.1;Renal connecting tubule cells: 235.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Thyroid Carcinoma (TCGA): 180.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030781 Uncertain NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 64: Non-specific - Transcription" "Cluster 30: White matter - Myelination" "Cluster 15: Kidney cancer - Membrane components" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 14 "HPA030781: " "unprognostic (1.17e-2)" "unprognostic (1.16e-2)" "unprognostic (4.26e-2)" "unprognostic (6.02e-3)" "unprognostic (3.41e-1)" "unprognostic (2.46e-1)" "unprognostic (3.09e-1)" "unprognostic (3.35e-2)" "unprognostic (1.83e-2)" "unprognostic (1.75e-2)" "unprognostic (2.95e-3)" "unprognostic (7.87e-2)" "unprognostic (3.60e-2)" "unprognostic (5.81e-3)" "unprognostic (4.48e-2)" "unprognostic (2.93e-3)" "unprognostic (2.79e-1)" "unprognostic (1.65e-2)" "unprognostic (1.24e-1)" "unprognostic (2.37e-1)" "unprognostic (8.12e-2)" "potential prognostic favorable (7.90e-4)" "unprognostic (3.42e-1)" "unprognostic (2.11e-2)" "unprognostic (9.91e-2)" "unprognostic (1.18e-1)" "unprognostic (1.11e-1)" "unprognostic (5.08e-2)" "unprognostic (1.63e-1)" "unprognostic (1.12e-1)" "unprognostic (8.24e-2)" SLC25A3 PHC ENSG00000075415 "Solute carrier family 25 member 3" Q00325 12 98593591-98606379 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 1205.5;Parietal cells: 1451.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045709 Supported Mitochondria NA NA 340000 "Cluster 33: Non-specific - ATP binding" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 38: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 25 Mitochondria "HPA045709: " "unprognostic (1.23e-2)" "unprognostic (1.94e-1)" "unprognostic (9.43e-2)" "unprognostic (3.05e-2)" "potential prognostic favorable (9.58e-4)" "unprognostic (1.89e-1)" "unprognostic (3.18e-2)" "unprognostic (4.12e-1)" "unprognostic (1.02e-2)" "unprognostic (7.95e-2)" "potential prognostic favorable (2.31e-5)" "unprognostic (1.40e-1)" "unprognostic (3.76e-2)" "unprognostic (7.99e-3)" "potential prognostic unfavorable (9.79e-7)" "potential prognostic unfavorable (7.28e-4)" "unprognostic (2.96e-2)" "unprognostic (8.06e-2)" "unprognostic (2.41e-1)" "unprognostic (4.10e-3)" "unprognostic (1.44e-2)" "unprognostic (2.56e-1)" "unprognostic (3.43e-2)" "unprognostic (3.86e-2)" "unprognostic (6.47e-2)" "unprognostic (5.90e-2)" "unprognostic (2.12e-1)" "unprognostic (2.13e-1)" "unprognostic (4.47e-1)" "unprognostic (2.77e-1)" "unprognostic (1.75e-1)" SLC25A30 ENSG00000174032 "Solute carrier family 25 member 30" Q5SVS4 13 45393316-45418455 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 67.0;skeletal muscle: 80.9;tongue: 59.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 43.0;Distal convoluted tubule cells: 71.3;Hepatocytes: 54.6;Myonuclei: 79.6;Renal connecting tubule cells: 58.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045260 Approved Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 21: Non-specific - Metabolism" "Cluster 15: Kidney cancer - Membrane components" "Cluster 55: Myocytes - Oxidative muscle function" 1 Nucleoplasm "HPA045260: " "unprognostic (1.16e-2)" "unprognostic (3.90e-1)" "unprognostic (5.04e-2)" "unprognostic (1.74e-3)" "unprognostic (6.74e-2)" "unprognostic (5.98e-2)" "unprognostic (1.02e-1)" "unprognostic (4.43e-3)" "unprognostic (3.13e-1)" "unprognostic (1.69e-1)" "validated prognostic favorable (1.57e-8)" "validated prognostic favorable (1.01e-4)" "unprognostic (1.08e-1)" "unprognostic (6.75e-3)" "unprognostic (2.93e-3)" "unprognostic (8.20e-2)" "unprognostic (4.54e-2)" "unprognostic (1.75e-1)" "unprognostic (1.80e-1)" "potential prognostic unfavorable (1.24e-4)" "unprognostic (3.09e-2)" "unprognostic (1.29e-1)" "unprognostic (1.41e-1)" "unprognostic (1.90e-1)" "unprognostic (8.98e-2)" "unprognostic (2.34e-3)" "unprognostic (6.63e-2)" "unprognostic (2.48e-1)" "unprognostic (1.95e-1)" "unprognostic (1.47e-1)" "unprognostic (3.07e-1)" SLC25A31 "ANT4, DKFZP434N1235" ENSG00000151475 "Solute carrier family 25 member 31" Q9H0C2 4 127730400-127774292 "Predicted membrane proteins, Transporters" "Antiport, Differentiation, Spermatogenesis, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 275 "testis: 44.2" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 22.2;Early primary spermatocytes: 167.1;Late primary spermatocytes: 248.7;Oocytes: 32.2;Undifferentiated spermatogonia: 60.1" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Spermatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015064, HPA016841, HPA046835, HPA071684" Uncertain Supported Mitochondria NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 24: Non-specific - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 17 Mitochondria "HPA015064: , HPA016841: , HPA046835: , HPA071684: " SLC25A32 MFTC ENSG00000164933 "Solute carrier family 25 member 32" Q9H2D1 8 103398635-103415189 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 21.6;Bergmann glia: 28.4;Brain excitatory neurons: 36.3;Brain inhibitory neurons: 29.5;Choroid plexus epithelial cells: 31.1;Distal convoluted tubule cells: 36.5;Loop of henle epithelial cells: 22.0;Microglia: 52.1;Oligodendrocyte progenitor cells: 39.7;Oligodendrocytes: 52.8;Other brain neurons: 30.5;Podocytes: 42.8;Proximal tubule cells: 25.0;Renal collecting duct intercalated cells: 28.5;Renal connecting tubule cells: 28.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024763, HPA047402" Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 24: Non-specific - Transcription" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 27: Non-specific - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 102: Non-specific - Mixed function" 4 Mitochondria Nucleoplasm "HPA024763: , HPA047402: " "unprognostic (6.06e-2)" "unprognostic (2.68e-3)" "unprognostic (8.87e-3)" "unprognostic (4.39e-2)" "unprognostic (1.18e-1)" "unprognostic (1.41e-1)" "unprognostic (1.04e-1)" "unprognostic (1.23e-1)" "unprognostic (4.86e-3)" "unprognostic (4.59e-1)" "unprognostic (1.24e-3)" "unprognostic (1.02e-1)" "unprognostic (1.99e-2)" "unprognostic (1.89e-2)" "unprognostic (3.08e-2)" "unprognostic (3.91e-2)" "unprognostic (1.50e-2)" "unprognostic (1.79e-2)" "unprognostic (1.35e-1)" "unprognostic (8.50e-3)" "potential prognostic unfavorable (8.84e-4)" "unprognostic (8.76e-2)" "unprognostic (3.48e-3)" "unprognostic (1.38e-1)" "unprognostic (6.54e-2)" "unprognostic (3.94e-2)" "unprognostic (2.20e-1)" "unprognostic (2.31e-1)" "unprognostic (1.06e-1)" "unprognostic (3.02e-3)" "unprognostic (1.17e-1)" SLC25A33 "BMSC-MCP, MGC4399, PNC1" ENSG00000171612 "Solute carrier family 25 member 33" Q9BSK2 1 9539465-9585173 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 25.7" "Cell type enhanced" "Detected in many" "Late spermatids: 332.9;Müller glia: 330.7" "Cell type enhanced" "Detected in all" "astrocyte: 173.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.8" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049982 Approved NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 11: Muller glia cells - Retinal homeostasis" 11 "HPA049982: " "unprognostic (2.86e-2)" "unprognostic (1.84e-2)" "unprognostic (1.85e-1)" "unprognostic (7.46e-3)" "unprognostic (1.46e-1)" "unprognostic (1.64e-1)" "unprognostic (2.27e-2)" "unprognostic (5.71e-2)" "unprognostic (5.21e-2)" "unprognostic (2.29e-2)" "unprognostic (2.12e-3)" "unprognostic (2.85e-3)" "unprognostic (1.37e-2)" "unprognostic (3.13e-2)" "unprognostic (5.77e-3)" "potential prognostic favorable (4.76e-4)" "unprognostic (8.87e-2)" "unprognostic (3.99e-2)" "unprognostic (2.81e-2)" "unprognostic (1.19e-1)" "unprognostic (2.77e-1)" "unprognostic (1.38e-1)" "unprognostic (6.35e-2)" "unprognostic (4.00e-1)" "unprognostic (6.08e-2)" "unprognostic (6.54e-2)" "unprognostic (3.34e-2)" "unprognostic (1.13e-1)" "unprognostic (1.36e-1)" "unprognostic (3.59e-3)" "unprognostic (1.35e-1)" SLC25A34 DKFZp781A10161 ENSG00000162461 "Solute carrier family 25 member 34" Q6PIV7 1 15736258-15741392 "Predicted membrane proteins, Transporters" Transport "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 4 "brain: 15.3;heart muscle: 13.4;intestine: 13.0;skeletal muscle: 36.5;tongue: 43.5" "Cell type enhanced" "Detected in many" "Colonocytes: 13.3;Enterocytes: 53.8;Myonuclei: 63.0;Tuft cells: 23.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in some" "Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069806 Approved Mitochondria NA NA "Cluster 11: T-cells - Unknown function" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 15: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 55: Myocytes - Oxidative muscle function" Mitochondria "HPA069806: " "unprognostic (3.51e-2)" "unprognostic (6.13e-2)" "unprognostic (7.95e-2)" "unprognostic (2.16e-1)" "unprognostic (2.87e-1)" "unprognostic (1.59e-3)" "unprognostic (2.58e-1)" "unprognostic (1.60e-3)" "potential prognostic favorable (6.90e-4)" "unprognostic (1.48e-2)" "unprognostic (8.27e-2)" "unprognostic (1.68e-2)" "unprognostic (4.14e-1)" "potential prognostic favorable (1.74e-4)" "unprognostic (2.21e-2)" "unprognostic (3.86e-1)" "unprognostic (1.16e-1)" "unprognostic (2.48e-1)" "unprognostic (1.20e-2)" "unprognostic (6.70e-2)" SLC25A35 FLJ40217 ENSG00000125434 "Solute carrier family 25 member 35" Q3KQZ1 17 8287763-8295400 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 97.6;Epicardial cells: 25.0;Syncytiotrophoblasts: 27.1" "Cell type enhanced" "Detected in many" "astrocyte: 13.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Skin - Sebaceous gland cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051720 Uncertain Approved Vesicles,Mitochondria NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 67: Testis - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 5: Rhabdoid - Unknown function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "Vesicles, Mitochondria" "HPA051720: " "unprognostic (8.83e-2)" "unprognostic (7.79e-2)" "unprognostic (1.69e-1)" "unprognostic (9.77e-3)" "unprognostic (5.10e-2)" "unprognostic (1.08e-2)" "unprognostic (9.04e-2)" "unprognostic (4.99e-1)" "unprognostic (3.57e-2)" "unprognostic (2.88e-2)" "unprognostic (2.12e-3)" "unprognostic (5.00e-2)" "potential prognostic favorable (7.12e-6)" "validated prognostic unfavorable (8.76e-4)" "validated prognostic unfavorable (8.90e-4)" "unprognostic (2.43e-1)" "unprognostic (9.28e-2)" "unprognostic (1.42e-1)" "unprognostic (1.39e-1)" "unprognostic (1.09e-1)" "unprognostic (4.27e-2)" "unprognostic (9.88e-3)" "unprognostic (1.06e-1)" "unprognostic (1.55e-1)" "unprognostic (1.61e-1)" "unprognostic (1.66e-1)" "unprognostic (2.56e-1)" "unprognostic (3.63e-2)" "unprognostic (2.45e-1)" "unprognostic (1.44e-1)" "unprognostic (1.70e-2)" SLC25A36 "FLJ10618, PNC2" ENSG00000114120 "Solute carrier family 25 member 36" Q96CQ1 3 140941830-140980995 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 409.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027036 Approved Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 55: Myocytes - Oxidative muscle function" "Mitochondria, Cytosol" Nucleoplasm "HPA027036: " "unprognostic (5.17e-3)" "unprognostic (6.66e-3)" "unprognostic (4.18e-1)" "unprognostic (3.90e-2)" "unprognostic (4.26e-3)" "unprognostic (1.56e-1)" "unprognostic (3.69e-1)" "unprognostic (3.39e-3)" "unprognostic (2.98e-1)" "unprognostic (5.41e-2)" "unprognostic (9.74e-3)" "unprognostic (1.56e-1)" "unprognostic (1.01e-1)" "unprognostic (7.04e-2)" "unprognostic (1.30e-1)" "unprognostic (6.34e-3)" "unprognostic (6.57e-2)" "unprognostic (3.21e-2)" "unprognostic (3.17e-2)" "unprognostic (2.06e-1)" "unprognostic (1.19e-2)" "unprognostic (1.62e-1)" "unprognostic (1.71e-3)" "unprognostic (3.56e-2)" "unprognostic (1.26e-2)" "unprognostic (2.51e-2)" "unprognostic (4.15e-2)" "unprognostic (1.45e-1)" "unprognostic (3.41e-1)" "unprognostic (1.82e-2)" "unprognostic (1.54e-1)" SLC25A37 "HT015, MFRN, MFRN1, MSCP" ENSG00000147454 "Solute carrier family 25 member 37" Q9NYZ2 8 23528956-23575463 "Metabolic proteins, Predicted intracellular proteins, Transporters" "Ion transport, Iron transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 130.4" "Cell type enhanced" "Detected in all" "Adrenal cortex cells: 596.6;Breast lactating cells: 801.3;Early spermatids: 798.0;Erythrocyte progenitors: 1111.1;Erythrocytes: 2304.3;Late spermatids: 1652.1;Neutrophils: 4649.5" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 358.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 19 "neutrophil: 58.3" "Lineage enriched" "Detected in all" 19 "granulocytes: 58.3" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Spleen - Neutrophils_2, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045680 Uncertain Approved Mitochondria,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 15: Bone marrow - Innate immune response" "Cluster 53: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 24: Neutrophils - Innate immunity signal integration" 1 Mitochondria Cytosol "HPA045680: " "unprognostic (7.26e-2)" "unprognostic (4.37e-3)" "unprognostic (3.35e-3)" "unprognostic (7.82e-3)" "unprognostic (8.36e-2)" "unprognostic (6.01e-2)" "unprognostic (1.56e-1)" "unprognostic (1.61e-1)" "unprognostic (1.97e-1)" "unprognostic (2.44e-1)" "potential prognostic unfavorable (2.74e-6)" "unprognostic (6.00e-2)" "unprognostic (4.32e-2)" "unprognostic (1.01e-1)" "unprognostic (1.97e-2)" "unprognostic (3.62e-1)" "unprognostic (6.82e-3)" "unprognostic (1.53e-1)" "unprognostic (1.89e-1)" "unprognostic (5.44e-2)" "unprognostic (4.12e-1)" "unprognostic (5.23e-3)" "unprognostic (1.83e-2)" "unprognostic (2.25e-1)" "unprognostic (1.16e-1)" "unprognostic (7.29e-2)" "unprognostic (7.42e-2)" "unprognostic (1.80e-1)" "unprognostic (3.31e-1)" "unprognostic (1.73e-1)" "unprognostic (4.83e-2)" SLC25A38 FLJ20551 ENSG00000144659 "Solute carrier family 25 member 38" Q96DW6 3 39383370-39397351 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 73.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Spleen - B-cells (Spleen), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041027 Approved NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" "HPA041027: " "unprognostic (1.04e-2)" "unprognostic (1.12e-2)" "unprognostic (8.68e-2)" "potential prognostic favorable (3.99e-4)" "unprognostic (6.37e-2)" "unprognostic (5.73e-1)" "unprognostic (8.35e-2)" "unprognostic (1.13e-1)" "unprognostic (8.00e-2)" "potential prognostic unfavorable (2.52e-4)" "validated prognostic favorable (2.90e-4)" "validated prognostic favorable (4.28e-4)" "unprognostic (3.46e-3)" "unprognostic (4.02e-2)" "unprognostic (8.84e-3)" "unprognostic (5.11e-2)" "unprognostic (1.71e-1)" "unprognostic (1.60e-1)" "unprognostic (1.95e-1)" "unprognostic (8.70e-2)" "unprognostic (5.11e-2)" "unprognostic (1.06e-1)" "unprognostic (2.28e-2)" "unprognostic (2.92e-2)" "unprognostic (5.80e-3)" "unprognostic (1.70e-1)" "unprognostic (1.40e-1)" "unprognostic (2.02e-1)" "unprognostic (4.83e-1)" "unprognostic (1.15e-1)" "unprognostic (3.38e-1)" SLC25A39 "CGI-69, FLJ22407" ENSG00000013306 "Solute carrier family 25 member 39" Q9BZJ4 17 44319625-44324870 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Heme biosynthesis, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocytes: 665.6;Esophageal apical cells: 643.8;Esophageal suprabasal cells: 393.3;Late spermatids: 1349.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Erythrocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026785 Approved NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 27: Breast cancer - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" "HPA026785: " "unprognostic (1.48e-1)" "unprognostic (1.56e-3)" "unprognostic (4.93e-1)" "unprognostic (1.38e-1)" "unprognostic (2.45e-1)" "unprognostic (1.01e-1)" "unprognostic (3.66e-3)" "unprognostic (1.00e-1)" "potential prognostic unfavorable (3.38e-5)" "unprognostic (4.39e-1)" "unprognostic (4.89e-2)" "unprognostic (7.33e-3)" "unprognostic (5.62e-2)" "validated prognostic unfavorable (9.50e-6)" "validated prognostic unfavorable (6.79e-7)" "unprognostic (2.54e-3)" "unprognostic (1.17e-2)" "unprognostic (4.86e-2)" "unprognostic (3.98e-2)" "unprognostic (1.74e-1)" "unprognostic (4.26e-1)" "unprognostic (1.74e-1)" "unprognostic (2.95e-1)" "unprognostic (3.43e-2)" "unprognostic (1.43e-1)" "unprognostic (1.78e-1)" "unprognostic (1.83e-1)" "unprognostic (1.51e-1)" "unprognostic (3.26e-1)" "unprognostic (1.75e-1)" "unprognostic (1.69e-1)" SLC25A4 "AAC1, ANT1, PEO2, PEO3, T1" ENSG00000151729 "Solute carrier family 25 member 4" P12235 4 185143266-185150382 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Host-virus interaction, Transport" "Cardiomyopathy, Disease variant, FDA approved drug targets, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "heart muscle: 240.1;skeletal muscle: 191.3;tongue: 323.8" "Cell type enhanced" "Detected in many" "Müller glia: 426.2;Myonuclei: 362.7;Parietal cells: 671.8;Retinal pigment epithelial cells: 383.7;Thymic myoid cells: 1306.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Stomach - Parietal cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046835, HPA071684" Approved Supported Mitochondria NA NA 650000 "Cluster 24: Non-specific - Transcription" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 37: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 57 Mitochondria "HPA046835: , HPA071684: " "unprognostic (1.24e-2)" "unprognostic (6.71e-3)" "unprognostic (1.53e-2)" "unprognostic (7.87e-3)" "unprognostic (1.84e-2)" "unprognostic (1.30e-2)" "unprognostic (1.06e-1)" "unprognostic (1.30e-1)" "unprognostic (1.91e-3)" "unprognostic (1.16e-1)" "validated prognostic favorable (2.03e-7)" "validated prognostic favorable (5.60e-5)" "potential prognostic favorable (1.31e-6)" "unprognostic (1.53e-1)" "unprognostic (3.16e-1)" "unprognostic (2.54e-2)" "unprognostic (4.18e-2)" "unprognostic (1.06e-2)" "unprognostic (1.02e-1)" "unprognostic (1.26e-1)" "unprognostic (1.37e-1)" "unprognostic (1.78e-3)" "unprognostic (2.55e-2)" "unprognostic (3.18e-1)" "unprognostic (1.65e-1)" "unprognostic (5.57e-2)" "unprognostic (3.85e-2)" "unprognostic (1.28e-1)" "unprognostic (8.61e-2)" "unprognostic (1.87e-2)" "unprognostic (5.83e-2)" SLC25A40 MCFP ENSG00000075303 "Solute carrier family 25 member 40" Q8TBP6 7 87833568-87876360 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophil progenitors: 233.2;Neutrophils: 131.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055197 Uncertain NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 25 "HPA055197: " "unprognostic (4.88e-3)" "unprognostic (3.63e-1)" "unprognostic (8.20e-2)" "unprognostic (3.39e-2)" "unprognostic (1.95e-1)" "unprognostic (9.28e-2)" "unprognostic (6.11e-2)" "unprognostic (2.39e-1)" "unprognostic (1.18e-1)" "potential prognostic unfavorable (9.72e-5)" "potential prognostic favorable (3.62e-6)" "unprognostic (1.15e-2)" "unprognostic (2.04e-2)" "potential prognostic unfavorable (9.65e-4)" "unprognostic (1.14e-3)" "unprognostic (2.25e-2)" "unprognostic (1.62e-1)" "unprognostic (9.34e-3)" "unprognostic (1.46e-1)" "unprognostic (1.64e-1)" "unprognostic (1.43e-1)" "unprognostic (3.31e-1)" "unprognostic (1.14e-1)" "unprognostic (7.94e-2)" "unprognostic (1.06e-1)" "unprognostic (2.27e-2)" "unprognostic (5.43e-2)" "unprognostic (1.78e-1)" "unprognostic (2.14e-1)" "unprognostic (9.34e-3)" "unprognostic (1.05e-1)" SLC25A41 "APC4, FLJ40442, MGC34725" ENSG00000181240 "Solute carrier family 25 member 41" Q8N5S1 19 6426037-6433779 "Predicted intracellular proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.1;testis: 2.1" "Cell type enriched" "Detected in some" 8 "Early spermatids: 280.3" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA043591 Uncertain NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 1 "HPA043591: " SLC25A42 MGC26694 ENSG00000181035 "Solute carrier family 25 member 42" Q86VD7 19 19063994-19113030 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 76.0" "Cell type enhanced" "Detected in many" "Hepatocytes: 88.7;Myonuclei: 182.5;Proximal tubule cells: 182.0;Retinal bipolar cells: 111.4;Rod photoreceptor cells: 78.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 2.8;MAIT T-cell: 1.5;memory B-cell: 3.3;memory CD4 T-cell: 1.6;memory CD8 T-cell: 2.4;naive B-cell: 3.2;naive CD4 T-cell: 1.0;naive CD8 T-cell: 1.5;NK-cell: 1.8;T-reg: 1.7" "Group enriched" "Detected in many" 6 "B-cells: 3.3;NK-cells: 1.8;T-cells: 2.8" "Cancer enhanced" "Detected in all" "Myeloma: 22.5" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Minor Salivary Gland - Minor salivary glandular cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049449 Approved Supported Mitochondria Yes No "Cluster 16: Non-specific - Cell proliferation" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 55: Myocytes - Oxidative muscle function" 3 Mitochondria "HPA049449: " "unprognostic (1.23e-1)" "unprognostic (1.74e-1)" "unprognostic (5.14e-3)" "unprognostic (3.12e-3)" "unprognostic (9.57e-2)" "unprognostic (2.94e-2)" "unprognostic (1.75e-1)" "unprognostic (2.50e-2)" "unprognostic (1.27e-3)" "unprognostic (8.74e-3)" "potential prognostic favorable (8.43e-8)" "unprognostic (1.36e-3)" "unprognostic (3.02e-3)" "potential prognostic favorable (9.81e-4)" "unprognostic (2.67e-3)" "potential prognostic favorable (3.35e-4)" "unprognostic (2.94e-1)" "unprognostic (3.17e-1)" "unprognostic (3.37e-3)" "unprognostic (7.87e-2)" "unprognostic (3.02e-2)" "unprognostic (1.01e-2)" "unprognostic (4.21e-2)" "unprognostic (1.33e-2)" "unprognostic (2.41e-1)" "unprognostic (6.88e-2)" "unprognostic (1.77e-1)" "unprognostic (1.95e-2)" "unprognostic (6.35e-2)" "unprognostic (1.83e-3)" "unprognostic (2.21e-1)" SLC25A43 ENSG00000077713 "Solute carrier family 25 member 43" Q8WUT9 X 119399336-119454478 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 239.7;Esophageal suprabasal cells: 178.0;Fibro-adipogenic progenitors: 144.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA035188, HPA078530" Uncertain Approved Cytosol NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 12: Non-specific - Vasculature" "Cluster 36: Non-specific - mRNA processing" "Cluster 85: Squamous epithelial cells - Keratinization" Cytosol "HPA035188: , HPA078530: " "unprognostic (3.25e-1)" "unprognostic (1.70e-3)" "unprognostic (3.89e-1)" "unprognostic (1.06e-1)" "unprognostic (8.79e-2)" "unprognostic (1.49e-1)" "unprognostic (1.08e-2)" "potential prognostic unfavorable (2.40e-4)" "unprognostic (1.55e-2)" "potential prognostic unfavorable (3.25e-4)" "unprognostic (1.22e-3)" "unprognostic (4.90e-3)" "unprognostic (2.51e-2)" "unprognostic (2.21e-3)" "unprognostic (3.53e-2)" "unprognostic (1.41e-2)" "potential prognostic unfavorable (5.96e-4)" "unprognostic (2.89e-1)" "unprognostic (5.12e-2)" "unprognostic (2.58e-2)" "unprognostic (2.32e-1)" "unprognostic (1.08e-2)" "unprognostic (3.21e-2)" "unprognostic (3.57e-1)" "unprognostic (1.57e-1)" "unprognostic (1.47e-1)" "unprognostic (5.41e-2)" "unprognostic (5.54e-2)" "unprognostic (2.10e-1)" "unprognostic (6.87e-3)" "unprognostic (5.50e-2)" SLC25A44 "FLJ90431, KIAA0446" ENSG00000160785 "Solute carrier family 25 member 44" Q96H78 1 156193932-156212796 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 164.3;Endometrial luminal cells: 87.9;Late spermatids: 147.3;Neutrophils: 116.7;Salivary basal cells: 170.6;Salivary myoepithelial cells: 151.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 71.4" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065411 Approved Nucleoplasm,Mitochondria NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 1: Neurons - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 103: Non-specific - Basic cellular processes" Mitochondria Nucleoplasm "HPA065411: " "unprognostic (4.65e-2)" "unprognostic (3.91e-2)" "unprognostic (2.03e-1)" "unprognostic (1.21e-1)" "unprognostic (6.92e-2)" "unprognostic (6.09e-2)" "unprognostic (3.78e-1)" "unprognostic (2.34e-2)" "unprognostic (2.26e-1)" "unprognostic (5.65e-3)" "potential prognostic favorable (2.28e-5)" "unprognostic (5.43e-2)" "unprognostic (1.47e-1)" "unprognostic (5.49e-2)" "unprognostic (2.70e-1)" "unprognostic (4.46e-2)" "unprognostic (1.75e-1)" "unprognostic (8.87e-2)" "unprognostic (3.76e-1)" "unprognostic (1.04e-1)" "unprognostic (1.73e-1)" "potential prognostic favorable (1.55e-4)" "unprognostic (1.22e-1)" "unprognostic (1.13e-1)" "unprognostic (4.15e-2)" "unprognostic (7.15e-3)" "unprognostic (2.27e-1)" "unprognostic (1.89e-1)" "unprognostic (5.27e-1)" "unprognostic (7.12e-2)" "unprognostic (1.23e-1)" SLC25A45 ENSG00000162241 "Solute carrier family 25 member 45" Q8N413 11 65375192-65383701 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 32.3" "Cell type enhanced" "Detected in many" "Enterocytes: 89.3;Granulosa cells: 112.7;Pancreatic acinar cells: 68.2;Sertoli cells: 58.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Myeloma: 13.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA042495, HPA050821" Uncertain Approved Cytosol NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 8: Pancreas - Proteolysis" "Cluster 30: White matter - Myelination" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 46: Skeletal myocytes - Muscle structure & formation" Cytosol "HPA042495: , HPA050821: " "unprognostic (2.52e-2)" "unprognostic (2.58e-1)" "unprognostic (4.17e-2)" "unprognostic (1.04e-3)" "unprognostic (2.56e-3)" "unprognostic (1.17e-2)" "unprognostic (1.09e-1)" "unprognostic (9.08e-3)" "unprognostic (2.18e-3)" "unprognostic (3.97e-2)" "unprognostic (3.94e-2)" "unprognostic (1.43e-1)" "unprognostic (1.89e-3)" "potential prognostic unfavorable (6.10e-4)" "unprognostic (1.60e-2)" "unprognostic (4.09e-2)" "unprognostic (1.47e-1)" "unprognostic (8.38e-2)" "unprognostic (1.53e-1)" "unprognostic (3.79e-2)" "unprognostic (9.35e-2)" "unprognostic (2.25e-3)" "unprognostic (1.54e-2)" "unprognostic (1.08e-1)" "unprognostic (1.71e-1)" "unprognostic (1.53e-1)" "unprognostic (4.64e-2)" "unprognostic (1.49e-1)" "unprognostic (6.47e-2)" "unprognostic (1.84e-2)" "unprognostic (1.13e-2)" SLC25A46 ENSG00000164209 "Solute carrier family 25 member 46" Q96AG3 5 110738136-110765161 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 221.2;Late spermatids: 760.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039601, HPA071582" Approved Supported Mitochondria NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 36 Mitochondria "HPA039601: , HPA071582: " "unprognostic (2.41e-3)" "unprognostic (1.63e-1)" "unprognostic (3.18e-1)" "unprognostic (2.61e-1)" "unprognostic (1.52e-1)" "unprognostic (1.39e-3)" "unprognostic (1.62e-1)" "unprognostic (3.53e-2)" "unprognostic (9.54e-2)" "unprognostic (3.49e-3)" "potential prognostic favorable (1.59e-7)" "unprognostic (5.06e-3)" "unprognostic (1.39e-1)" "unprognostic (9.58e-2)" "unprognostic (1.14e-1)" "unprognostic (2.52e-1)" "unprognostic (1.28e-1)" "unprognostic (1.10e-1)" "unprognostic (3.04e-3)" "unprognostic (5.00e-2)" "potential prognostic unfavorable (4.18e-5)" "unprognostic (6.53e-2)" "unprognostic (1.23e-1)" "unprognostic (2.88e-2)" "unprognostic (1.96e-2)" "unprognostic (7.34e-3)" "unprognostic (1.64e-1)" "unprognostic (7.68e-2)" "unprognostic (1.39e-1)" "unprognostic (2.67e-3)" "unprognostic (1.45e-1)" SLC25A47 "C14orf68, HDCMP" ENSG00000140107 "Solute carrier family 25 member 47" Q6Q0C1 14 100323339-100330421 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 357 "liver: 508.8" "Cell type enriched" "Detected in some" 42 "Hepatocytes: 350.4" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 204 "Liver Hepatocellular Carcinoma (TCGA): 73.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 93: Hepatocytes - Bile production & excretion" "unprognostic (4.18e-2)" "unprognostic (5.85e-3)" SLC25A48 FLJ44862 ENSG00000145832 "Solute carrier family 25 member 48" Q6ZT89 5 135476913-135889770 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 14.8;kidney: 6.9;skeletal muscle: 6.3" "Cell type enhanced" "Detected in many" "Astrocytes: 158.4;Basal keratinocytes: 37.4;Endometrial glandular cells: 40.1;Fibro-adipogenic progenitors: 54.7;Loop of henle epithelial cells: 53.1;Pituicytes/FSCs: 128.3;Proximal tubule cells: 177.2;Retinal bipolar cells: 36.9" "Cell type enhanced" "Detected in many" "astrocyte: 179.5;CGE interneuron: 133.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 3.9;Rhabdoid: 3.6" "Minor Salivary Gland - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA014674 Uncertain Approved "Intermediate filaments,Actin filaments" NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 4 "Intermediate filaments" "Actin filaments" "HPA014674: " "unprognostic (2.28e-1)" "unprognostic (6.49e-2)" "unprognostic (1.47e-3)" "unprognostic (1.61e-2)" "unprognostic (1.80e-1)" "unprognostic (4.67e-2)" "potential prognostic favorable (4.30e-7)" "unprognostic (1.44e-3)" "potential prognostic favorable (1.95e-8)" "unprognostic (2.68e-2)" "unprognostic (4.93e-2)" "unprognostic (1.20e-1)" "unprognostic (2.57e-2)" "unprognostic (1.81e-1)" "unprognostic (1.31e-1)" "unprognostic (1.63e-1)" "unprognostic (5.41e-2)" SLC25A5 "2F1, ANT2, T2, T3" ENSG00000005022 "Solute carrier family 25 member 5" P05141 X 119468422-119471396 "Essential proteins, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Antiport, Chromosome partition, Host-virus interaction, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Colonocytes: 1652.3;Cytotrophoblasts: 1253.6;Enterocytes: 2509.5;Esophageal basal cells: 1847.6;Esophageal suprabasal cells: 1470.6;Parietal cells: 3995.5;Syncytiotrophoblasts: 1854.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary gland basal cells, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046835, HPA071684" Approved Supported Mitochondria NA NA 2000000 "Cluster 33: Non-specific - ATP binding" "Cluster 60: Stomach - Digestion" "Cluster 45: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 42 Mitochondria "HPA046835: , HPA071684: " "unprognostic (1.69e-3)" "potential prognostic unfavorable (4.66e-4)" "unprognostic (6.78e-3)" "potential prognostic favorable (1.22e-4)" "unprognostic (2.57e-2)" "unprognostic (3.63e-3)" "unprognostic (6.37e-2)" "unprognostic (9.09e-2)" "unprognostic (5.25e-3)" "unprognostic (2.96e-1)" "potential prognostic favorable (3.55e-5)" "unprognostic (4.65e-2)" "unprognostic (5.45e-2)" "unprognostic (2.11e-2)" "potential prognostic unfavorable (2.75e-4)" "unprognostic (1.40e-1)" "unprognostic (3.45e-2)" "unprognostic (1.48e-1)" "unprognostic (1.86e-1)" "unprognostic (1.89e-1)" "unprognostic (1.72e-1)" "unprognostic (1.66e-1)" "unprognostic (6.39e-2)" "unprognostic (6.86e-2)" "unprognostic (1.98e-2)" "unprognostic (1.10e-1)" "unprognostic (2.16e-1)" "unprognostic (2.46e-2)" "unprognostic (1.27e-1)" "unprognostic (5.91e-3)" "unprognostic (6.53e-2)" SLC25A51 "CG7943, MCART1, MGC14836" ENSG00000122696 "Solute carrier family 25 member 51" Q9H1U9 9 37879400-37904353 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 8 "Astrocytes: 22.2;Bergmann glia: 25.2;Brain excitatory neurons: 27.5;Brain inhibitory neurons: 29.3;Choroid plexus epithelial cells: 27.6;Ependymal cells: 13.8;Microglia: 20.3;Oligodendrocyte progenitor cells: 23.8;Oligodendrocytes: 27.8;Other brain neurons: 27.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 16.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 16.7" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Testis - Early spermatids, Testis - Late spermatids" "HPA046388, HPA058261" Uncertain Approved Mitochondria NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 14: Neurons - Synaptic function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 22: Non-specific - Basic cellular functions" 3 Mitochondria "HPA046388: , HPA058261: " "unprognostic (2.47e-2)" "unprognostic (1.64e-1)" "unprognostic (1.34e-1)" "unprognostic (7.57e-2)" "unprognostic (3.55e-2)" "unprognostic (2.40e-1)" "potential prognostic favorable (3.15e-4)" "unprognostic (4.78e-2)" "unprognostic (9.07e-2)" "unprognostic (2.68e-3)" "unprognostic (1.73e-3)" "unprognostic (5.54e-2)" "potential prognostic unfavorable (8.20e-6)" "unprognostic (9.33e-2)" "unprognostic (4.67e-3)" "unprognostic (2.20e-1)" "unprognostic (9.04e-2)" "unprognostic (6.98e-2)" "unprognostic (1.58e-1)" "unprognostic (5.76e-2)" "unprognostic (3.73e-3)" "unprognostic (1.26e-1)" "potential prognostic favorable (5.28e-4)" "unprognostic (7.96e-2)" "unprognostic (5.87e-2)" "unprognostic (1.36e-1)" "unprognostic (2.04e-1)" "potential prognostic unfavorable (3.13e-4)" "unprognostic (2.29e-1)" SLC25A52 MCART2 ENSG00000141437 "Solute carrier family 25 member 52" Q3SY17 18 31759584-31760880 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 15 "testis: 9.7" "Group enriched" "Detected in some" 39 "Early spermatids: 49.3;Late primary spermatocytes: 58.2;Late spermatids: 163.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "HPA046388, HPA058261" Uncertain Approved Mitochondria NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 1 Mitochondria "HPA046388: , HPA058261: " SLC25A53 MCART6 ENSG00000269743 "Solute carrier family 25 member 53" Q5H9E4 X 104099214-104157009 "Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.4;lymphoid tissue: 1.7" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 2.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 2.8" "Spleen - B-cells (Spleen), Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA034959 Uncertain NA NA "Cluster 18: Lymphoid tissue - Immune response" "Cluster 9: Non-specific - Receptor signaling" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 7: Non-specific - Transcription" "HPA034959: " "unprognostic (6.53e-2)" "unprognostic (1.98e-2)" "potential prognostic favorable (2.83e-5)" "unprognostic (2.01e-1)" SLC25A6 "ANT3, ANT3Y, MGC17525" ENSG00000169100 "Solute carrier family 25 member 6" P12236 X 1386152-1392113 "FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Antiport, Apoptosis, Host-virus interaction, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1900.0;Decidual stromal cells: 2369.3;Esophageal basal cells: 1951.9;Migrating cytotrophoblasts: 1842.8;Syncytiotrophoblasts: 1867.0" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "HPA046835, HPA071684" Approved Approved Mitochondria NA NA 870000 "Cluster 13: Non-specific - Mitochondria" "Cluster 70: Non-specific - Protein processing" "Cluster 23: Choroid plexus - Mixed function" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 94 Mitochondria "HPA046835: , HPA071684: " "unprognostic (1.22e-1)" "unprognostic (2.81e-1)" "unprognostic (1.64e-1)" "unprognostic (3.12e-2)" "unprognostic (1.06e-2)" "unprognostic (6.50e-3)" "unprognostic (1.64e-1)" "unprognostic (2.95e-1)" "unprognostic (1.42e-1)" "unprognostic (3.55e-3)" "unprognostic (2.45e-1)" "unprognostic (1.38e-1)" "unprognostic (7.11e-3)" "unprognostic (1.49e-1)" "unprognostic (1.65e-1)" "unprognostic (3.53e-2)" "unprognostic (1.58e-1)" "unprognostic (9.71e-2)" "unprognostic (4.17e-2)" "potential prognostic favorable (4.12e-4)" "unprognostic (2.28e-2)" "unprognostic (3.31e-1)" "unprognostic (7.00e-3)" "unprognostic (3.48e-1)" "unprognostic (1.93e-1)" "unprognostic (1.05e-1)" "unprognostic (7.55e-2)" "unprognostic (7.52e-2)" "unprognostic (3.36e-3)" SLC26A1 "EDM4, SAT-1" ENSG00000145217 "Solute carrier family 26 member 1" Q9H2B4 4 979073-993440 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Anion exchange, Antiport, Ion transport, Transport" "Ion channel" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 17.4" "Cell type enhanced" "Detected in some" "Adipocytes: 11.2;Cardiomyocytes: 10.3;Enterocytes: 6.3;Epicardial cells: 18.2;Extravillous trophoblasts: 5.4;Hepatocytes: 13.3;Proximal tubule cells: 6.1" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "basophil: 5.4" "Lineage enriched" "Detected in single" 6 "granulocytes: 5.4" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Liver - Hepatocytes" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA041654 Uncertain Approved Microtubules NA NA "Cluster 70: Non-specific - Protein processing" "Cluster 37: Neurons - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" Microtubules "HPA041654: " "unprognostic (8.98e-2)" "unprognostic (2.69e-2)" "unprognostic (3.25e-1)" "unprognostic (2.60e-2)" "unprognostic (3.08e-1)" "unprognostic (2.96e-2)" "unprognostic (2.15e-1)" "unprognostic (4.12e-2)" "potential prognostic favorable (6.92e-4)" "unprognostic (1.03e-3)" "unprognostic (1.34e-1)" "unprognostic (7.74e-2)" "unprognostic (1.13e-1)" "unprognostic (1.25e-1)" "unprognostic (1.61e-1)" "unprognostic (3.57e-2)" "unprognostic (2.02e-2)" "unprognostic (1.95e-2)" "potential prognostic favorable (8.16e-4)" "unprognostic (4.63e-2)" "unprognostic (1.58e-2)" "unprognostic (1.45e-1)" "unprognostic (3.55e-2)" "unprognostic (2.96e-2)" "unprognostic (1.90e-1)" "unprognostic (7.15e-2)" "unprognostic (3.81e-2)" SLC26A11 ENSG00000181045 "Solute carrier family 26 member 11" Q86WA9 17 80219699-80253500 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Anion exchange, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 65.8;Adrenal medulla cells: 95.7;Other brain neurons: 60.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029893 Approved Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 27: Breast cancer - Unknown function" "Cluster 109: Neurons - Neuronal signaling" 1 "Golgi apparatus, Vesicles" Nucleoplasm "HPA029893: " "unprognostic (2.39e-1)" "unprognostic (3.30e-1)" "unprognostic (4.43e-2)" "unprognostic (3.68e-2)" "unprognostic (2.52e-2)" "unprognostic (2.56e-3)" "unprognostic (1.43e-1)" "unprognostic (8.72e-2)" "unprognostic (5.67e-3)" "unprognostic (4.54e-3)" "unprognostic (3.16e-2)" "unprognostic (2.28e-2)" "unprognostic (4.50e-2)" "potential prognostic unfavorable (1.87e-5)" "unprognostic (3.40e-3)" "unprognostic (1.75e-2)" "unprognostic (2.24e-1)" "unprognostic (1.45e-1)" "unprognostic (6.60e-3)" "unprognostic (1.50e-1)" "unprognostic (3.95e-2)" "potential prognostic favorable (7.65e-6)" "unprognostic (3.86e-3)" "unprognostic (2.82e-1)" "unprognostic (1.92e-1)" "unprognostic (4.25e-2)" "unprognostic (3.06e-2)" "unprognostic (2.18e-2)" "unprognostic (3.72e-1)" "unprognostic (1.31e-1)" "unprognostic (7.76e-2)" SLC26A2 "DTD, DTDST" ENSG00000155850 "Solute carrier family 26 member 2" P50443 5 149960758-149993455 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "intestine: 198.2" "Group enriched" "Detected in many" 4 "Colonocytes: 2057.7;Endometrial glandular cells: 673.4;Endometrial luminal cells: 1205.4;Syncytiotrophoblasts: 1034.7" "Cell type enhanced" "Detected in all" "fibroblast: 186.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 4.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Colon - Colon enterocytes, Minor Salivary Gland - Minor salivary glandular cells, Skin - Eccrine sweat gland cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041957, HPA058090" Enhanced Approved Vesicles NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 17: Intestine - Digestion" "Cluster 25: Non-specific - Transcription" "Cluster 69: Skin cancer - ECM organization" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 7 Vesicles "HPA041957: , HPA058090: " "unprognostic (2.10e-1)" "unprognostic (1.07e-1)" "unprognostic (3.42e-1)" "unprognostic (1.89e-1)" "unprognostic (3.37e-2)" "unprognostic (3.04e-2)" "unprognostic (1.24e-2)" "unprognostic (1.50e-2)" "unprognostic (1.13e-1)" "unprognostic (2.70e-3)" "unprognostic (1.97e-3)" "unprognostic (8.65e-2)" "unprognostic (3.74e-1)" "unprognostic (3.04e-3)" "potential prognostic unfavorable (4.71e-4)" "unprognostic (5.81e-2)" "unprognostic (7.48e-3)" "unprognostic (6.49e-2)" "unprognostic (1.41e-2)" "unprognostic (6.32e-2)" "unprognostic (3.79e-2)" "unprognostic (1.48e-1)" "unprognostic (4.38e-2)" "unprognostic (2.29e-1)" "unprognostic (7.83e-2)" "unprognostic (4.02e-2)" "unprognostic (1.08e-1)" "unprognostic (1.61e-1)" "unprognostic (2.92e-1)" "unprognostic (2.77e-2)" "unprognostic (1.83e-2)" SLC26A3 "CLD, DRA" ENSG00000091138 "Solute carrier family 26 member 3" P40879 7 107765467-107803225 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "intestine: 1050.9" "Group enriched" "Detected in many" 4 "Colonocytes: 4022.8;Enterocytes: 1364.6" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" 13 "Colon Adenocarcinoma (TCGA): 77.5;Rectum Adenocarcinoma (TCGA): 94.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 25 "colorectal cancer: 16.6" "Breast - Breast glandular cells, Colon - Colon enterocytes, Skin - Sebaceous gland cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA036055 Enhanced Approved Acrosome NA NA "Cluster 77: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 1 Acrosome "HPA036055: " "unprognostic (1.49e-2)" "unprognostic (2.15e-1)" "unprognostic (3.43e-2)" "unprognostic (2.87e-2)" "unprognostic (1.30e-3)" "unprognostic (4.94e-2)" "unprognostic (1.55e-1)" "unprognostic (5.30e-2)" "unprognostic (4.19e-2)" "unprognostic (2.10e-2)" "unprognostic (1.20e-1)" "unprognostic (2.66e-2)" SLC26A4 "DFNB4, PDS" ENSG00000091137 "Solute carrier family 26 member 4" O43511 7 107660828-107717809 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 29 "thyroid gland: 247.4" "Cell type enriched" "Detected in many" 4 "Renal collecting duct intercalated cells: 442.7" "Cell type enhanced" "Detected in many" "deep-layer intratelencephalic: 108.4;hippocampal CA1-3: 144.5;MGE interneuron: 108.7;miscellaneous: 103.6" "Cancer enriched" "Detected in some" 10 "Thyroid Carcinoma (TCGA): 119.3" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 8 "naive B-cell: 1.0" "Lineage enriched" "Detected in single" 8 "B-cells: 1.0" "Cancer enriched" "Detected in some" 7 "lymphoma: 16.1" "Kidney - Intercalated cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Region enriched" "Detected in many" 4 "hippocampal formation: 9.7" "Region enhanced" "Detected in many" "hippocampal formation: 6.6" HPA042860 Approved NA NA "Cluster 33: Thyroid gland - Tissue development" "Cluster 51: Neurons - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 3 "HPA042860: " "unprognostic (5.44e-2)" "unprognostic (2.64e-2)" "unprognostic (1.85e-1)" "unprognostic (9.28e-3)" "unprognostic (4.66e-2)" "unprognostic (3.28e-2)" "unprognostic (2.70e-1)" "unprognostic (5.77e-2)" "unprognostic (8.99e-3)" SLC26A5 "DFNB61, PRES" ENSG00000170615 "Solute carrier family 26 member 5" P58743 7 103352730-103446207 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cell shape, Hearing" "Motor protein" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 87.0;Epicardial cells: 97.8;Foveolar cells: 70.8;Gonadotrophs: 89.4;Prostatic glandular cells: 92.3;Prostatic hillock cells: 71.4;Respiratory ciliated cells: 62.0" "Cell type enhanced" "Detected in all" "upper rhombic lip: 69.8" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebellum: 4.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Prostate - Prostate glandular cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Region enhanced" "Detected in all" "basal ganglia: 14.5" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 25: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "unprognostic (3.05e-2)" SLC26A6 DKFZp586E1422 ENSG00000225697 "Solute carrier family 26 member 6" Q9BXS9 3 48625723-48635493 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Anion exchange, Antiport, Ion transport, Transport" "Chloride channel, Ion channel, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 59.1;Enterocytes: 41.5;Goblet cells: 41.4;Mucous neck cells: 34.3;Proximal tubule cells: 51.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048363, HPA072381" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 77: Intestine - Digestion" "Cluster 6: Non-specific - Immune response" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 2 "Plasma membrane" Cytosol "HPA048363: , HPA072381: " "unprognostic (3.94e-2)" "unprognostic (8.05e-2)" "unprognostic (9.99e-2)" "unprognostic (1.31e-2)" "unprognostic (1.19e-1)" "unprognostic (1.21e-1)" "unprognostic (2.29e-2)" "unprognostic (4.87e-1)" "unprognostic (2.94e-2)" "potential prognostic unfavorable (4.14e-5)" "potential prognostic unfavorable (8.94e-7)" "unprognostic (3.96e-1)" "unprognostic (2.66e-2)" "potential prognostic unfavorable (4.27e-4)" "unprognostic (9.74e-3)" "unprognostic (1.24e-3)" "unprognostic (1.06e-2)" "unprognostic (1.22e-1)" "unprognostic (1.17e-1)" "unprognostic (3.16e-1)" "unprognostic (1.04e-1)" "unprognostic (4.36e-1)" "unprognostic (1.60e-2)" "unprognostic (3.86e-2)" "unprognostic (7.37e-2)" "unprognostic (2.19e-1)" "unprognostic (2.49e-2)" "unprognostic (4.54e-3)" "unprognostic (2.37e-2)" "unprognostic (4.97e-3)" "unprognostic (1.49e-1)" SLC26A7 SUT2 ENSG00000147606 "Solute carrier family 26 member 7" Q8TE54 8 91209494-91398155 "Metabolic proteins, Predicted membrane proteins, Transporters" "Anion exchange, Ion transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "thyroid gland: 310.2" "Cell type enriched" "Detected in many" 20 "Renal collecting duct intercalated cells: 3971.2" "Cell type enhanced" "Detected in many" "fibroblast: 41.6" "Group enriched" "Detected in some" 24 "Kidney Chromophobe (TCGA): 117.6;Thyroid Carcinoma (TCGA): 33.2" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 11 "Rhabdoid: 21.4" "Kidney - Intercalated cells, Stomach - Parietal cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA023107, HPA053032" Supported "Golgi apparatus,Vesicles,Perinuclear theca,Mid piece" NA NA "Cluster 33: Thyroid gland - Tissue development" "Cluster 11: White matter - Signal transduction" "Cluster 3: Rhabdoid - Membrane components" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" Vesicles "Golgi apparatus, Perinuclear theca, Mid piece" "HPA023107: , HPA053032: " "unprognostic (1.03e-1)" "unprognostic (8.09e-2)" "unprognostic (5.28e-2)" "unprognostic (2.23e-1)" "unprognostic (3.54e-2)" "unprognostic (2.41e-1)" "unprognostic (4.37e-3)" "unprognostic (1.48e-1)" SLC26A8 TAT1 ENSG00000112053 "Solute carrier family 26 member 8" Q96RN1 6 35943516-36024868 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Anion exchange, Differentiation, Ion transport, Meiosis, Spermatogenesis, Transport" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "testis: 41.2" "Group enriched" "Detected in many" 4 "Late primary spermatocytes: 152.1;Neutrophil progenitors: 104.7;Neutrophils: 268.2" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 11 "neutrophil: 2.5" "Lineage enriched" "Detected in single" 11 "granulocytes: 2.5" "Not detected" "Not detected" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Lung - Neutrophils_2, Minor Salivary Gland - Minor salivary glandular cells, Spleen - Neutrophils_2, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA038080, HPA038081, HPA061393" Enhanced Approved Acrosome,Annulus NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 24: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 3 Annulus Acrosome "HPA038080: , HPA038081: , HPA061393: " "unprognostic (2.49e-1)" "unprognostic (6.16e-2)" SLC26A9 ENSG00000174502 "Solute carrier family 26 member 9" Q7LBE3 1 205913048-205943460 "Metabolic proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "salivary gland: 68.3;stomach 1: 32.0" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 92.8;Conjunctival goblet cells: 15.5;Epicardial cells: 50.0;Esophageal apical cells: 18.8;Foveolar cells: 61.6;Parietal cells: 90.2;Salivary basal cells: 16.3;Salivary duct cells: 25.1;Transitional alveolar cells: 34.8" "Cell type enhanced" "Detected in some" "oligodendrocyte: 4.1" "Group enriched" "Detected in many" 5 "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 3.7;Lung Adenocarcinoma (TCGA): 12.9;Pancreatic Adenocarcinoma (TCGA): 9.5;Stomach Adenocarcinoma (TCGA): 5.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 3.5;pancreatic cancer: 3.6" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary gland ductal cells, Pancreas - Ductal cells, Skeletal muscle - Skeletal myocytes, Stomach - Parietal cells, Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA051485 Enhanced Uncertain "Cell Junctions" NA NA "Cluster 82: Salivary gland - Secretion" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 81: Alveolar cells - Lung function" "Cell Junctions" "HPA051485: " "unprognostic (3.15e-2)" "unprognostic (1.70e-1)" "potential prognostic favorable (3.29e-5)" "unprognostic (5.84e-2)" "unprognostic (8.04e-2)" "unprognostic (1.56e-2)" "unprognostic (7.47e-3)" "unprognostic (3.05e-1)" "unprognostic (1.37e-1)" "potential prognostic favorable (2.52e-4)" "unprognostic (9.86e-2)" "unprognostic (1.14e-1)" "unprognostic (2.32e-1)" "unprognostic (1.87e-1)" SLC27A1 "ACSVL5, FATP, FATP1, FLJ00336, MGC71751" ENSG00000130304 "Solute carrier family 27 member 1" Q6PCB7 19 17468769-17506168 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Lipid transport, Transport" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 130.4;Bergmann glia: 163.1;Cardiomyocytes: 136.7;Choroid plexus epithelial cells: 220.9;Myonuclei: 139.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076520 Approved "Plasma membrane,Mitochondria,Cytosol" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 30: White matter - Myelination" "Cluster 69: Skin cancer - ECM organization" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 17 "Plasma membrane" "Mitochondria, Cytosol" "HPA076520: " "unprognostic (1.27e-1)" "unprognostic (8.36e-2)" "unprognostic (6.93e-3)" "unprognostic (3.02e-2)" "unprognostic (1.01e-1)" "unprognostic (7.39e-2)" "unprognostic (1.87e-2)" "unprognostic (1.13e-3)" "unprognostic (5.85e-2)" "unprognostic (6.27e-2)" "potential prognostic favorable (1.40e-5)" "unprognostic (3.16e-1)" "unprognostic (2.02e-2)" "unprognostic (5.13e-2)" "unprognostic (3.17e-3)" "unprognostic (1.75e-2)" "unprognostic (2.80e-1)" "unprognostic (1.13e-1)" "unprognostic (2.07e-1)" "unprognostic (9.80e-3)" "unprognostic (3.39e-3)" "unprognostic (1.76e-1)" "unprognostic (1.46e-1)" "unprognostic (1.59e-1)" "unprognostic (1.50e-2)" "unprognostic (3.77e-2)" "unprognostic (1.84e-1)" "unprognostic (1.62e-1)" "unprognostic (2.25e-1)" "unprognostic (9.69e-2)" "unprognostic (6.98e-3)" SLC27A2 "ACSVL1, FACVL1, FATP2, hFACVL1, HsT17226, VLACS, VLCS" ENSG00000140284 "Solute carrier family 27 member 2" O14975 15 50182196-50236385 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Lipid transport, Transport" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 147.1;liver: 269.2" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 134.0;Cytotrophoblasts: 406.2;Enterocytes: 86.9;Epididymal efferent duct absorptive cells: 83.6;Epididymal principal cells: 98.3;Hepatocytes: 300.1;Lactotrophs: 101.7;Migrating cytotrophoblasts: 117.3;Proximal tubule cells: 233.3;Respiratory ciliated cells: 172.1;Respiratory secretory cells: 131.2;Retinal pigment epithelial cells: 93.8" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 80.5" "Region enhanced" "Detected in all" "choroid plexus: 20.1" "Immune cell enriched" "Detected in some" 30 "basophil: 63.7" "Lineage enriched" "Detected in many" 30 "granulocytes: 63.7" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Pituitary gland - Lactotropes, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026089 Enhanced NA NA "Cluster 41: Basophils - Unknown function" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 42 "HPA026089: " "unprognostic (1.66e-1)" "unprognostic (3.12e-2)" "unprognostic (1.67e-2)" "unprognostic (1.75e-1)" "unprognostic (3.68e-2)" "unprognostic (3.76e-2)" "unprognostic (2.04e-1)" "unprognostic (4.43e-3)" "validated prognostic favorable (9.05e-12)" "validated prognostic favorable (7.62e-5)" "unprognostic (9.95e-2)" "unprognostic (3.58e-3)" "potential prognostic favorable (2.35e-4)" "unprognostic (1.88e-2)" "unprognostic (4.57e-2)" "unprognostic (1.34e-2)" "unprognostic (1.38e-1)" "unprognostic (1.46e-2)" "unprognostic (2.24e-2)" "unprognostic (4.32e-2)" "unprognostic (2.24e-1)" "unprognostic (1.81e-1)" "unprognostic (1.33e-3)" "unprognostic (1.41e-1)" "unprognostic (1.80e-2)" "unprognostic (2.68e-1)" "unprognostic (1.01e-1)" "unprognostic (4.70e-2)" SLC27A3 "ACSVL3, FATP3, MGC4365" ENSG00000143554 "Solute carrier family 27 member 3" Q5K4L6 1 153774354-153780157 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Lipid transport, Transport" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 5 "Epididymal principal cells: 146.8" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 53.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "dendritic cells: 7.4;granulocytes: 12.6;monocytes: 11.1" "Cancer enriched" "Detected in many" 5 "skin cancer: 20.9" "Minor Salivary Gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067508, CAB080514, CAB080517" Enhanced Approved "Endoplasmic reticulum,Mitochondria" Yes No "Cluster 25: Non-specific - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 20 "Endoplasmic reticulum, Mitochondria" "CAB080514: , CAB080517: , HPA067508: " "unprognostic (1.90e-1)" "unprognostic (1.60e-1)" "unprognostic (1.29e-1)" "unprognostic (5.32e-2)" "unprognostic (1.74e-1)" "unprognostic (2.18e-1)" "unprognostic (3.61e-2)" "potential prognostic unfavorable (1.31e-4)" "unprognostic (2.14e-1)" "unprognostic (1.27e-1)" "unprognostic (1.52e-1)" "unprognostic (4.81e-2)" "unprognostic (8.36e-2)" "unprognostic (2.05e-1)" "unprognostic (1.14e-1)" "unprognostic (3.21e-2)" "unprognostic (3.26e-1)" "unprognostic (1.76e-1)" "unprognostic (5.12e-2)" "unprognostic (2.88e-2)" "potential prognostic favorable (2.64e-4)" "unprognostic (2.29e-2)" "unprognostic (4.43e-3)" "potential prognostic favorable (1.18e-4)" "unprognostic (1.85e-3)" "unprognostic (1.63e-1)" "unprognostic (1.85e-2)" "unprognostic (2.01e-1)" "unprognostic (1.38e-1)" "unprognostic (1.93e-1)" "unprognostic (2.10e-2)" SLC27A4 "ACSVL4, FATP4" ENSG00000167114 "Solute carrier family 27 member 4" Q6P1M0 9 128340527-128361470 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Lipid transport, Transport" Ligase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 571.6;Enteric transient amplifying cells: 198.6;Enterocytes: 313.6;Epididymal clear cells: 234.8;Esophageal apical cells: 207.1;Foveolar cells: 392.4;Gastric chief cells: 310.1;Gastric progenitor cells: 232.0;Goblet cells: 278.0;Megakaryocytes: 234.9;Parietal cells: 272.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Macrophages, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007293, CAB009771" Approved Approved Vesicles NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 15: Non-specific - Protein processing" 30 Vesicles "CAB009771: , HPA007293: " "unprognostic (9.54e-2)" "unprognostic (7.28e-2)" "unprognostic (9.47e-2)" "unprognostic (3.17e-1)" "unprognostic (1.48e-1)" "unprognostic (1.82e-1)" "unprognostic (1.93e-1)" "unprognostic (3.71e-2)" "unprognostic (1.59e-1)" "unprognostic (2.41e-1)" "unprognostic (3.94e-2)" "unprognostic (2.90e-1)" "potential prognostic favorable (1.23e-4)" "unprognostic (2.23e-3)" "unprognostic (5.27e-2)" "unprognostic (8.53e-3)" "unprognostic (2.63e-1)" "unprognostic (4.43e-2)" "unprognostic (1.27e-2)" "unprognostic (2.44e-2)" "unprognostic (3.37e-1)" "unprognostic (9.65e-2)" "unprognostic (5.90e-3)" "unprognostic (1.70e-1)" "unprognostic (1.91e-1)" "unprognostic (5.64e-2)" "unprognostic (1.23e-1)" "unprognostic (5.11e-2)" "unprognostic (3.27e-1)" "unprognostic (8.34e-2)" "unprognostic (3.22e-2)" SLC27A5 "ACSB, ACSVL6, FACVL3, FATP5, FLJ22987, VLACSR, VLCS-H2, VLCSH2" ENSG00000083807 "Solute carrier family 27 member 5" Q9Y2P5 19 58479512-58512413 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Lipid transport, Transport" "Ligase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 24 "liver: 989.3" "Group enriched" "Detected in many" 4 "Hepatocytes: 554.8;Late spermatids: 807.7" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 11 "Liver Hepatocellular Carcinoma (TCGA): 386.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA007292, CAB056160, CAB068239" Enhanced NA NA "Cluster 24: Non-specific - Transcription" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 19: Astrocytes - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" "CAB056160: , CAB068239: , HPA007292: " "unprognostic (6.70e-2)" "unprognostic (1.82e-1)" "unprognostic (2.05e-1)" "unprognostic (1.00e-3)" "unprognostic (9.53e-2)" "unprognostic (2.89e-2)" "unprognostic (2.88e-1)" "unprognostic (3.49e-1)" "unprognostic (2.66e-2)" "unprognostic (9.73e-2)" "unprognostic (3.19e-2)" "unprognostic (1.01e-3)" "unprognostic (5.13e-3)" "validated prognostic favorable (1.95e-4)" "validated prognostic favorable (7.43e-5)" "unprognostic (1.79e-2)" "unprognostic (1.17e-1)" "unprognostic (1.66e-2)" "unprognostic (2.08e-1)" "unprognostic (2.31e-1)" "unprognostic (4.64e-2)" "unprognostic (5.98e-2)" "unprognostic (1.70e-1)" "unprognostic (1.26e-1)" "unprognostic (8.39e-2)" "unprognostic (3.80e-1)" "unprognostic (6.26e-3)" "unprognostic (5.36e-2)" "unprognostic (6.15e-2)" "unprognostic (1.39e-2)" "unprognostic (2.91e-1)" SLC27A6 "ACSVL2, FACVL2, FATP6, VLCS-H1" ENSG00000113396 "Solute carrier family 27 member 6" Q9Y2P4 5 128538013-129033642 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Lipid transport, Transport" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 23.0;fallopian tube: 20.0;heart muscle: 22.0" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 85.6;Cardiomyocytes: 342.4;Cytotrophoblasts: 97.2;Ependymal cells: 99.6;Extravillous trophoblasts: 63.4;Migrating cytotrophoblasts: 139.7;Müller glia: 73.5;Myosatellite cells: 84.3;Pituicytes/FSCs: 228.1;Pituitary stem cells: 70.8;Sertoli cells: 156.6" "Group enriched" "Detected in many" 4 "ependymal cell: 117.2;LAMP5-LHX6 and Chandelier: 124.7;MGE interneuron: 88.9;midbrain-derived inhibitory: 242.9;splatter: 70.0" "Cancer enriched" "Detected in many" 9 "Thyroid Carcinoma (TCGA): 37.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 5.1" "Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA008987 Approved Approved "Nuclear bodies" NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 43: Hindbrain - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 13 "Nuclear bodies" "HPA008987: " "unprognostic (5.46e-3)" "potential prognostic favorable (7.92e-5)" "unprognostic (1.43e-1)" "unprognostic (2.89e-1)" "unprognostic (2.52e-1)" "unprognostic (1.33e-1)" "unprognostic (3.49e-2)" "unprognostic (2.01e-1)" "unprognostic (2.57e-1)" "unprognostic (8.92e-2)" "unprognostic (2.24e-1)" SLC28A1 CNT1 ENSG00000156222 "Solute carrier family 28 member 1" O00337 15 84884654-84945798 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 21 "intestine: 46.2;kidney: 46.6;liver: 106.7" "Group enriched" "Detected in many" 6 "Enterocytes: 248.3;Hepatocytes: 149.8;Hofbauer cells: 123.5;Proximal tubule cells: 406.1" "Cell type enhanced" "Detected in some" "astrocyte: 7.2;ependymal cell: 6.0" "Cancer enhanced" "Detected in some" "Kidney Renal Clear Cell Carcinoma (TCGA): 101.5;Kidney Renal Papillary Cell Carcinoma (TCGA): 48.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "Kidney cancer: 3.9" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA019551, HPA056247" Enhanced Approved "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 16: Liver & Kidney - Metabolism" "Cluster 30: White matter - Myelination" "Cluster 15: Kidney cancer - Membrane components" "Cluster 88: Proximal tubular cells - Transmembrane transport" "Plasma membrane" "Nuclear speckles, Cytosol" "HPA019551: , HPA056247: " "unprognostic (3.46e-2)" "validated prognostic favorable (4.02e-5)" "validated prognostic favorable (4.28e-4)" "potential prognostic favorable (2.14e-4)" "unprognostic (2.84e-2)" "potential prognostic favorable (7.20e-5)" SLC28A2 "CNT2, HCNT2, HsT17153, SPNT1" ENSG00000137860 "Solute carrier family 28 member 2" O43868 15 45252234-45277846 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "intestine: 86.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 56.7;Colonocytes: 46.4;Cytotrophoblasts: 20.1;Enteric stem cells: 31.7;Enteric transient amplifying cells: 39.2;Enterocytes: 63.3;Foveolar cells: 135.9;Mucous neck cells: 38.5;Myonuclei: 21.3" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Stomach Adenocarcinoma (TCGA): 6.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "Gastric cancer: 7.6" "Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046068, HPA055623" Enhanced Uncertain Vesicles NA NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 9: Non-specific - Receptor signaling" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 68: Foveolar cells - Mucosal defense" 1 Vesicles "HPA046068: , HPA055623: " "unprognostic (4.96e-2)" "unprognostic (3.93e-2)" "unprognostic (2.40e-2)" "unprognostic (1.20e-3)" "unprognostic (1.80e-3)" "unprognostic (1.88e-1)" "unprognostic (1.40e-1)" "unprognostic (1.54e-1)" "unprognostic (9.74e-2)" "unprognostic (6.20e-2)" "unprognostic (1.04e-1)" "unprognostic (2.19e-1)" "unprognostic (8.09e-2)" SLC28A3 CNT3 ENSG00000197506 "Solute carrier family 28 member 3" Q9HAS3 9 84275457-84340758 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 31.6" "Cell type enhanced" "Detected in many" "Breast secretory cells: 49.2;Choroid plexus epithelial cells: 138.5;Endometrial glandular cells: 48.6;Esophageal apical cells: 61.0;Esophageal suprabasal cells: 43.1;Fallopian secretory cells: 67.1;Fallopian tube ciliated cells: 37.5;Mesothelial cells: 118.4;Neutrophil progenitors: 39.6;Pancreatic duct cells: 135.0;Salivary acinar cells: 60.0" "Group enriched" "Detected in some" 37 "choroid plexus epithelial cell: 134.8;ependymal cell: 46.7" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 22 "choroid plexus: 47.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 2.5;Leukemia: 2.6" "Adipose visceral - Mesothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Spleen - Neutrophils_1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA023311, HPA024729" Approved NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 51: Secretory epithelial cells - Mixed function" 1 "HPA023311: , HPA024729: " "unprognostic (5.11e-2)" "potential prognostic favorable (8.35e-4)" "unprognostic (2.42e-2)" "unprognostic (1.22e-2)" "unprognostic (1.73e-1)" "unprognostic (1.55e-2)" "unprognostic (7.98e-3)" "unprognostic (1.98e-1)" "unprognostic (6.11e-2)" "unprognostic (3.07e-2)" "unprognostic (7.85e-2)" "unprognostic (8.93e-2)" "unprognostic (8.55e-2)" "unprognostic (3.04e-1)" "unprognostic (4.68e-2)" "unprognostic (1.75e-1)" "unprognostic (2.13e-1)" "unprognostic (9.52e-3)" "unprognostic (6.67e-2)" "unprognostic (1.91e-1)" "unprognostic (9.12e-2)" SLC29A1 ENT1 ENSG00000112759 "Solute carrier family 29 member 1 (Augustine blood group)" Q99808 6 44219553-44234142 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 127.6;Cytotrophoblasts: 266.7;Extravillous trophoblasts: 278.6;Granulosa cells: 117.6;Migrating cytotrophoblasts: 214.7;Oocytes: 253.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 26 "eosinophil: 1049.2" "Lineage enriched" "Detected in all" 26 "granulocytes: 1049.2" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Spleen - Macrophages, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012384 Approved NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 24: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 15 "HPA012384: " "unprognostic (2.66e-1)" "unprognostic (4.92e-3)" "unprognostic (9.28e-2)" "unprognostic (8.97e-3)" "unprognostic (2.27e-1)" "unprognostic (2.43e-1)" "unprognostic (5.97e-2)" "unprognostic (2.23e-1)" "unprognostic (2.23e-2)" "unprognostic (1.00e-1)" "unprognostic (4.94e-2)" "unprognostic (1.53e-1)" "potential prognostic unfavorable (1.37e-4)" "unprognostic (2.10e-1)" "unprognostic (2.43e-1)" "unprognostic (2.00e-2)" "unprognostic (1.35e-1)" "unprognostic (5.45e-2)" "unprognostic (7.00e-2)" "unprognostic (2.78e-1)" "unprognostic (9.95e-2)" "unprognostic (1.29e-2)" "unprognostic (1.36e-1)" "unprognostic (1.49e-1)" "unprognostic (8.01e-2)" "unprognostic (9.26e-2)" "unprognostic (1.99e-1)" "unprognostic (1.25e-2)" "unprognostic (9.23e-2)" "unprognostic (7.44e-2)" "unprognostic (2.85e-2)" SLC29A2 "DER12, ENT2, HNP36" ENSG00000174669 "Solute carrier family 29 member 2" Q14542 11 66362521-66372214 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "skeletal muscle: 85.0;tongue: 44.1" "Cell type enhanced" "Detected in many" "Bergmann glia: 42.8;Cardiomyocytes: 37.8;Cytotrophoblasts: 64.0;Migrating cytotrophoblasts: 41.2;Myonuclei: 172.9;Thymic myoid cells: 129.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018168 Approved NA Yes "Cluster 11: T-cells - Unknown function" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 44: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 1 "HPA018168: " "unprognostic (6.59e-2)" "unprognostic (4.25e-1)" "unprognostic (1.04e-1)" "unprognostic (1.15e-2)" "unprognostic (3.17e-2)" "unprognostic (2.71e-1)" "unprognostic (2.31e-1)" "unprognostic (5.16e-2)" "unprognostic (4.02e-2)" "unprognostic (1.36e-1)" "unprognostic (1.91e-1)" "unprognostic (2.03e-1)" "unprognostic (1.03e-1)" "unprognostic (9.65e-3)" "unprognostic (2.09e-2)" "unprognostic (7.22e-2)" "unprognostic (8.59e-2)" "unprognostic (2.47e-1)" "unprognostic (1.01e-1)" "unprognostic (2.69e-1)" "unprognostic (2.13e-2)" "unprognostic (7.81e-2)" "unprognostic (5.17e-2)" "unprognostic (2.20e-3)" "unprognostic (1.19e-2)" "unprognostic (4.56e-1)" "unprognostic (3.34e-3)" "unprognostic (9.05e-3)" "unprognostic (3.57e-2)" "unprognostic (6.45e-2)" "unprognostic (1.64e-1)" SLC29A3 "ENT3, FLJ11160, hENT3" ENSG00000198246 "Solute carrier family 29 member 3" Q9BZD2 10 71319259-71381423 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 57.1;Extravillous trophoblasts: 62.1;Hofbauer cells: 33.8;Kupffer cells: 36.9;Late spermatids: 34.5;Microglia: 75.3;Migrating cytotrophoblasts: 57.0;Oocytes: 36.8;Syncytiotrophoblasts: 35.8" "Cell type enriched" "Detected in many" 6 "central nervous system macrophage: 95.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Kidney - Fibroblasts, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046085, HPA054976, HPA057905" Approved Enhanced "Golgi apparatus,Vesicles" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 63: Cytotrophoblasts - Basic cellular functions" "Golgi apparatus, Vesicles" "HPA046085: , HPA054976: , HPA057905: " "unprognostic (1.38e-1)" "unprognostic (2.43e-2)" "unprognostic (1.57e-1)" "unprognostic (9.54e-2)" "unprognostic (8.95e-2)" "unprognostic (1.43e-1)" "unprognostic (1.68e-1)" "unprognostic (2.28e-2)" "unprognostic (7.73e-2)" "unprognostic (1.45e-1)" "unprognostic (7.54e-2)" "unprognostic (2.84e-1)" "validated prognostic unfavorable (2.33e-5)" "validated prognostic unfavorable (5.85e-4)" "unprognostic (2.27e-2)" "unprognostic (8.33e-2)" "unprognostic (5.63e-2)" "unprognostic (7.79e-2)" "unprognostic (1.00e-1)" "unprognostic (5.90e-2)" "unprognostic (3.03e-1)" "unprognostic (1.13e-1)" "unprognostic (1.38e-1)" "unprognostic (1.01e-1)" "unprognostic (2.16e-1)" "unprognostic (1.14e-2)" "unprognostic (6.37e-2)" "unprognostic (2.05e-2)" "unprognostic (3.98e-2)" "unprognostic (3.42e-2)" SLC29A4 "ENT4, FLJ34923" ENSG00000164638 "Solute carrier family 29 member 4" Q7RTT9 7 5274369-5306912 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 40.7;brain: 32.2;choroid plexus: 35.3" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 74.5;Bergmann glia: 52.4;Choroid plexus epithelial cells: 75.6;Neuroendocrine cells: 112.1;Oocytes: 59.9;Pancreatic islet cells: 66.3;Retinal amacrine cells: 61.6;Retinal horizontal cells: 210.4;Retinal pigment epithelial cells: 89.5" "Cell type enhanced" "Detected in many" "hippocampal dentate gyrus: 91.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Neuroblastoma: 39.9" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal medulla cells, Breast - Adipocytes (Breast), Pancreas - Alpha cells, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052829 Approved "Microtubules,Cytokinetic bridge" Yes No "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 19: Astrocytes - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" "Microtubules, Cytokinetic bridge" "HPA052829: " "unprognostic (1.41e-1)" "unprognostic (1.92e-1)" "unprognostic (9.72e-2)" "unprognostic (1.95e-1)" "unprognostic (1.31e-2)" "unprognostic (1.26e-2)" "potential prognostic unfavorable (8.36e-4)" "unprognostic (3.77e-1)" "unprognostic (7.78e-2)" "unprognostic (1.96e-1)" "unprognostic (1.30e-2)" "unprognostic (1.66e-2)" "unprognostic (3.96e-3)" "unprognostic (1.10e-2)" "unprognostic (1.45e-2)" "unprognostic (2.77e-1)" "unprognostic (3.14e-1)" "unprognostic (9.22e-2)" "unprognostic (1.20e-3)" "unprognostic (1.73e-2)" "unprognostic (1.09e-1)" "unprognostic (1.32e-3)" "unprognostic (1.63e-2)" "unprognostic (1.95e-1)" "unprognostic (2.22e-1)" "unprognostic (3.69e-3)" "unprognostic (7.57e-2)" "potential prognostic unfavorable (5.62e-4)" "unprognostic (1.79e-1)" "unprognostic (1.91e-3)" "unprognostic (2.54e-2)" SLC2A1 "CSE, DYT18, DYT9, GLUT, GLUT-1, GLUT1, HTLVR" ENSG00000117394 "Solute carrier family 2 member 1" P11166 1 42925353-42958893 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Cancer-related genes, Cataract, Disease variant, Dystonia, Epilepsy, Hereditary hemolytic anemia, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 92.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 987.3;Esophageal apical cells: 672.8;Extravillous trophoblasts: 730.6;Migrating cytotrophoblasts: 755.2;Müller glia: 484.8;Ocular epithelial cells: 855.1;Prostatic hillock cells: 375.5;Retinal pigment epithelial cells: 362.4;Syncytiotrophoblasts: 2979.0;Urothelial cells: 457.0" "Cell type enriched" "Detected in all" 8 "endothelial cell: 678.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary gland basal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002759, HPA031345, HPA058494" Enhanced Supported Enhanced "Plasma membrane,Centriolar satellite" No No 2500000 "Cluster 14: Non-specific - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 47: Endothelial cells - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 90 "Plasma membrane" "Centriolar satellite" "CAB002759: , HPA031345: , HPA058494: " "unprognostic (1.47e-1)" "unprognostic (1.82e-1)" "unprognostic (6.77e-3)" "unprognostic (2.23e-3)" "unprognostic (3.13e-2)" "unprognostic (1.92e-2)" "unprognostic (4.46e-2)" "unprognostic (2.70e-3)" "unprognostic (2.41e-1)" "potential prognostic unfavorable (7.39e-4)" "unprognostic (7.25e-3)" "unprognostic (3.93e-1)" "potential prognostic unfavorable (7.22e-4)" "validated prognostic unfavorable (2.32e-6)" "validated prognostic unfavorable (9.77e-4)" "validated prognostic unfavorable (5.40e-9)" "validated prognostic unfavorable (3.54e-4)" "unprognostic (5.29e-3)" "unprognostic (3.59e-2)" "unprognostic (2.92e-2)" "unprognostic (5.33e-2)" "potential prognostic unfavorable (8.01e-4)" "unprognostic (2.14e-3)" "unprognostic (1.90e-1)" "unprognostic (2.44e-1)" "unprognostic (8.35e-2)" "unprognostic (8.37e-3)" "unprognostic (2.89e-2)" "unprognostic (2.38e-1)" "unprognostic (1.65e-3)" "unprognostic (1.64e-1)" SLC2A10 "GLUT-10, GLUT10" ENSG00000197496 "Solute carrier family 2 member 10" O95528 20 46709649-46736347 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 52.5;Foveolar cells: 58.1;Goblet cells: 84.3;Hepatocytes: 59.7;Prostatic glandular cells: 102.3;Respiratory secretory cells: 51.2" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 31.8;fibroblast: 45.6" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "choroid plexus: 38.6" "Immune cell enriched" "Detected in single" 82 "basophil: 20.8" "Lineage enriched" "Detected in single" 82 "granulocytes: 20.8" "Cancer enhanced" "Detected in many" "breast cancer: 30.6" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Adrenal gland - Fibroblasts, Liver - Hepatocytes, Prostate - Prostate glandular cells, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA041015, HPA055673" Approved Supported Cytosol NA NA "Cluster 70: Non-specific - Protein processing" "Cluster 36: Choroid plexus - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 70: Intestinal goblet cells - Mucin production" Cytosol "HPA041015: , HPA055673: " "unprognostic (1.87e-2)" "unprognostic (1.45e-2)" "unprognostic (1.64e-1)" "unprognostic (6.53e-3)" "unprognostic (5.99e-2)" "unprognostic (2.05e-2)" "unprognostic (3.76e-3)" "potential prognostic unfavorable (5.56e-6)" "unprognostic (6.50e-2)" "unprognostic (2.52e-1)" "unprognostic (4.87e-2)" "unprognostic (2.01e-2)" "unprognostic (5.07e-2)" "unprognostic (3.01e-1)" "unprognostic (4.26e-3)" "unprognostic (1.19e-2)" "unprognostic (2.90e-2)" "unprognostic (6.65e-2)" "unprognostic (6.78e-2)" "unprognostic (2.01e-1)" "unprognostic (2.68e-3)" "unprognostic (9.44e-3)" "unprognostic (2.62e-1)" "unprognostic (4.79e-1)" "unprognostic (5.05e-1)" "unprognostic (7.61e-2)" "unprognostic (2.40e-1)" "unprognostic (5.41e-3)" "unprognostic (8.65e-2)" "unprognostic (3.29e-1)" "unprognostic (2.31e-1)" SLC2A11 GLUT11 ENSG00000133460 "Solute carrier family 2 member 11" Q9BYW1 22 23856703-23886312 "Metabolic proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 14.2;Platelets: 23.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "HPA042960, HPA071184" Uncertain Uncertain "Nucleoplasm,Cell Junctions" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" "Cell Junctions" Nucleoplasm "HPA042960: , HPA071184: " "unprognostic (3.19e-2)" "unprognostic (4.26e-3)" "unprognostic (9.56e-2)" "unprognostic (1.77e-1)" "unprognostic (8.38e-2)" "unprognostic (1.44e-1)" "unprognostic (6.60e-2)" "unprognostic (2.41e-2)" "unprognostic (2.20e-1)" "potential prognostic favorable (3.20e-4)" "unprognostic (4.39e-3)" "potential prognostic favorable (9.07e-10)" "unprognostic (1.17e-1)" "potential prognostic favorable (7.92e-5)" "unprognostic (1.09e-1)" "unprognostic (2.63e-1)" "unprognostic (1.00e-2)" "unprognostic (9.09e-2)" "unprognostic (1.02e-2)" "unprognostic (1.59e-3)" "unprognostic (1.14e-1)" "unprognostic (2.84e-2)" "unprognostic (9.55e-3)" "unprognostic (1.01e-2)" "unprognostic (2.08e-1)" "unprognostic (3.41e-1)" "unprognostic (9.60e-2)" "unprognostic (7.11e-2)" "unprognostic (6.26e-2)" SLC2A12 "GLUT12, GLUT8" ENSG00000146411 "Solute carrier family 2 member 12" Q8TD20 6 133987581-134052624 "Metabolic proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "choroid plexus: 102.3" "Group enriched" "Detected in many" 6 "Choroid plexus epithelial cells: 992.6;Retinal pigment epithelial cells: 601.1" "Cell type enriched" "Detected in many" 10 "choroid plexus epithelial cell: 843.7" "Cancer enriched" "Detected in many" 5 "Prostate Adenocarcinoma (TCGA): 35.0" "Region enriched" "Detected in all" 11 "choroid plexus: 184.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 19.9" "Adipose subcutaneous - Smooth muscle cells, Breast - Breast myoepithelial cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031593, HPA031594" Approved Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 1 "Plasma membrane" "Cell Junctions" "HPA031593: , HPA031594: " "unprognostic (2.81e-3)" "unprognostic (3.97e-1)" "unprognostic (4.97e-2)" "unprognostic (8.07e-3)" "unprognostic (2.19e-1)" "unprognostic (1.28e-1)" "unprognostic (1.13e-1)" "unprognostic (3.18e-1)" "unprognostic (9.21e-2)" "unprognostic (1.94e-1)" "unprognostic (6.52e-3)" "unprognostic (1.01e-2)" "unprognostic (1.30e-1)" "unprognostic (1.35e-2)" "unprognostic (2.70e-2)" "unprognostic (1.84e-1)" "unprognostic (4.04e-2)" "unprognostic (6.22e-2)" "unprognostic (3.34e-2)" "unprognostic (2.20e-2)" "unprognostic (1.65e-1)" "unprognostic (2.07e-1)" "potential prognostic favorable (2.64e-4)" "unprognostic (2.84e-1)" "unprognostic (4.34e-1)" SLC2A13 HMIT ENSG00000151229 "Solute carrier family 2 member 13" Q96QE2 12 39755025-40106089 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.2;parathyroid gland: 21.3" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 506.4;Choroid plexus epithelial cells: 905.4;Foveolar cells: 366.2;Goblet cells: 380.7;Lactotrophs: 442.6;Oligodendrocyte progenitor cells: 411.1;Other brain neurons: 468.6;Retinal horizontal cells: 560.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006584, HPA061679" Enhanced Approved "Nuclear membrane" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 73: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 109: Neurons - Neuronal signaling" 4 "Nuclear membrane" "HPA006584: , HPA061679: " "unprognostic (3.97e-2)" "unprognostic (1.97e-1)" "unprognostic (3.22e-1)" "unprognostic (7.44e-2)" "unprognostic (9.13e-2)" "unprognostic (5.29e-2)" "unprognostic (8.42e-2)" "unprognostic (1.25e-2)" "unprognostic (3.63e-1)" "unprognostic (2.64e-2)" "potential prognostic favorable (2.09e-7)" "unprognostic (9.14e-2)" "unprognostic (3.49e-2)" "unprognostic (3.80e-2)" "unprognostic (1.44e-1)" "unprognostic (1.08e-1)" "unprognostic (2.56e-1)" "unprognostic (1.15e-1)" "unprognostic (6.39e-2)" "unprognostic (2.32e-1)" "unprognostic (2.21e-1)" "unprognostic (1.10e-1)" "unprognostic (2.00e-1)" "unprognostic (9.45e-2)" "unprognostic (6.85e-2)" "unprognostic (3.94e-2)" "unprognostic (2.59e-1)" "unprognostic (1.21e-2)" "unprognostic (1.32e-2)" SLC2A14 "GLUT14, SLC2A3P3" ENSG00000173262 "Solute carrier family 2 member 14" Q8TDB8 12 7812512-7891148 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Spermatogenesis, Sugar transport, Transport" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "testis: 76.4" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 89.3;Early primary spermatocytes: 64.0;Erythrocyte progenitors: 45.7;Granulosa cells: 61.6;Late primary spermatocytes: 103.0;Megakaryocyte-Erythroid progenitors: 23.4;Neutrophils: 38.6;Pancreatic acinar cells: 109.4" "Cell type enhanced" "Detected in many" "hippocampal CA4: 19.3" "Cancer enriched" "Detected in many" 11 "Testicular Germ Cell Tumor (TCGA): 25.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.7;neutrophil: 3.3" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in many" 6 "testis cancer: 32.7" "Skin - Sebaceous gland cells, Testis - Early spermatids" HPA006539 Supported Supported "Plasma membrane" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 57: Testis - Spermatogenesis" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 34: Testis cancer - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" "Plasma membrane" "HPA006539: " "unprognostic (5.04e-3)" "unprognostic (3.35e-2)" "unprognostic (5.84e-2)" "unprognostic (1.90e-1)" "unprognostic (2.00e-2)" "unprognostic (4.07e-2)" "potential prognostic unfavorable (3.62e-7)" "unprognostic (1.52e-1)" "unprognostic (1.15e-1)" "unprognostic (1.61e-1)" "unprognostic (4.18e-2)" "unprognostic (3.42e-1)" "unprognostic (3.52e-2)" "unprognostic (3.92e-2)" "unprognostic (9.44e-2)" "unprognostic (1.46e-1)" "unprognostic (2.70e-1)" "unprognostic (1.19e-1)" "unprognostic (1.16e-1)" "unprognostic (2.55e-1)" "unprognostic (2.78e-2)" SLC2A2 "GLUT-2, GLUT2" ENSG00000163581 "Solute carrier family 2 member 2" P11168 3 170996347-171026743 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "liver: 781.9" "Cell type enhanced" "Detected in some" "Cholangiocytes: 141.1;Enterocytes: 226.3;Hepatocytes: 749.7;Proximal tubule cells: 56.5" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 3.6;fibroblast: 4.6;oligodendrocyte: 6.1" "Cancer enriched" "Detected in some" 9 "Liver Hepatocellular Carcinoma (TCGA): 135.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 4.6;Kidney cancer: 6.4;liver cancer: 4.0" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB010444, HPA028997, HPA069490" Enhanced Supported "Plasma membrane,Mid piece,Principal piece" NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 11: White matter - Signal transduction" "Cluster 15: Kidney cancer - Membrane components" "Cluster 93: Hepatocytes - Bile production & excretion" 3 "Plasma membrane, Mid piece, Principal piece" "CAB010444: , HPA028997: , HPA069490: " "potential prognostic favorable (1.10e-5)" "unprognostic (7.97e-2)" "unprognostic (7.92e-2)" "potential prognostic favorable (1.70e-5)" "unprognostic (1.46e-2)" "unprognostic (3.32e-1)" "unprognostic (2.02e-2)" SLC2A3 GLUT3 ENSG00000059804 "Solute carrier family 2 member 3" P11169 12 7919230-7936187 "Metabolic proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 404.4" "Cell type enhanced" "Detected in many" "cDC: 488.0;Decidual stromal cells: 608.8;Extravillous trophoblasts: 653.6;Mast cells: 611.2;Migrating cytotrophoblasts: 434.8;monocytes: 1083.6;Neutrophil progenitors: 528.2;Neutrophils: 2917.4;Pericytes: 419.9;Platelets: 623.0;T-cells: 549.8;Vascular endothelial cells: 769.0" "Cell type enhanced" "Detected in all" "endothelial cell: 423.8;leukocyte: 381.3" "Cancer enriched" "Detected in all" 5 "Testicular Germ Cell Tumor (TCGA): 269.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "basophil: 166.9;neutrophil: 225.3" "Lineage enriched" "Detected in all" 9 "granulocytes: 225.3" "Cancer enriched" "Detected in many" 7 "testis cancer: 1031.5" "CAB002763, HPA006539" Approved Supported "Plasma membrane" NA NA 6800000 "Cluster 35: Neutrophils - Protein binding" "Cluster 15: Bone marrow - Innate immune response" "Cluster 1: Neurons - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 3 "Plasma membrane" "CAB002763: , HPA006539: " "unprognostic (3.56e-2)" "unprognostic (1.71e-1)" "unprognostic (7.30e-2)" "unprognostic (7.41e-2)" "unprognostic (2.48e-2)" "unprognostic (3.61e-1)" "potential prognostic unfavorable (4.47e-4)" "unprognostic (2.60e-2)" "unprognostic (1.11e-3)" "unprognostic (3.42e-1)" "unprognostic (7.00e-2)" "unprognostic (1.81e-2)" "unprognostic (1.81e-1)" "unprognostic (6.61e-2)" "unprognostic (1.95e-1)" "unprognostic (2.34e-1)" "unprognostic (2.28e-3)" "unprognostic (1.01e-1)" "unprognostic (4.53e-1)" "unprognostic (3.32e-3)" "unprognostic (3.78e-1)" "unprognostic (2.08e-2)" "unprognostic (2.13e-3)" "unprognostic (8.10e-2)" "unprognostic (1.25e-1)" "unprognostic (8.13e-3)" "unprognostic (3.01e-1)" "potential prognostic unfavorable (1.31e-4)" "unprognostic (2.37e-1)" "unprognostic (4.75e-3)" "unprognostic (8.18e-2)" SLC2A4 GLUT4 ENSG00000181856 "Solute carrier family 2 member 4" P14672 17 7281718-7288257 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 95.4;skeletal muscle: 219.2" "Cell type enhanced" "Detected in some" "Astrocytes: 4.8;Bergmann glia: 1.3;Cardiomyocytes: 4.6;Distal convoluted tubule cells: 1.2;Epicardial cells: 2.3;Myonuclei: 1.1;Pericytes: 1.7;Smooth muscle cells: 3.4;Thymic myoid cells: 1.4;Vascular smooth muscle cells: 2.7" "Group enriched" "Detected in some" 6 "pericyte: 27.1;vascular associated smooth muscle cell: 32.0" "Cancer enriched" "Detected in some" 6 "Kidney Chromophobe (TCGA): 8.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" CAB016544 Enhanced NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 47: Leukemia - Hemostasis" "Cluster 22: Non-specific - Basic cellular functions" 17 "CAB016544: " "unprognostic (1.15e-1)" "unprognostic (4.45e-2)" "unprognostic (9.28e-2)" "unprognostic (8.79e-2)" "unprognostic (4.54e-3)" "unprognostic (1.41e-2)" "unprognostic (7.50e-3)" "unprognostic (1.85e-1)" "unprognostic (2.08e-1)" SLC2A4RG "GEF, HDBP1, Si-1-2, Si-1-2-19" ENSG00000125520 "SLC2A4 regulator" Q9NR83 20 63739776-63744050 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 85.5" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 104.2;Hepatocytes: 142.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Stomach - Fibroblasts" "Low region specificity" "Detected in all" HPA063050 Approved "Nuclear speckles" NA NA "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 39: Astrocytes - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 20: Non-specific - Transcription regulation" "Nuclear speckles" "HPA063050: " "unprognostic (1.19e-1)" "unprognostic (1.64e-1)" "unprognostic (6.84e-2)" "unprognostic (2.31e-1)" "unprognostic (4.86e-2)" "unprognostic (1.29e-1)" "unprognostic (5.48e-2)" "unprognostic (1.67e-2)" "unprognostic (6.74e-2)" "unprognostic (6.31e-2)" "unprognostic (1.04e-1)" "unprognostic (4.63e-2)" "unprognostic (2.57e-3)" "unprognostic (1.21e-1)" "unprognostic (8.51e-2)" "unprognostic (1.63e-2)" "unprognostic (8.82e-2)" "unprognostic (2.59e-2)" "unprognostic (2.96e-1)" "unprognostic (1.90e-1)" "unprognostic (3.35e-2)" "unprognostic (5.84e-2)" "potential prognostic unfavorable (3.64e-4)" "unprognostic (1.95e-1)" "unprognostic (4.09e-1)" "unprognostic (1.00e-1)" "unprognostic (1.14e-1)" "unprognostic (8.02e-2)" "unprognostic (3.62e-1)" "unprognostic (3.02e-2)" "unprognostic (1.97e-1)" SLC2A5 GLUT5 ENSG00000142583 "Solute carrier family 2 member 5" P22732 1 9035106-9088478 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 91.5;intestine: 102.6;skeletal muscle: 73.9;testis: 71.3" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 32.5;Early spermatids: 51.2;Enterocytes: 211.9;Hematopoietic stem cells: 48.5;Late primary spermatocytes: 158.2;Microglia: 179.4;Myonuclei: 35.3;Neutrophil progenitors: 80.2;Plasma cells: 38.7" "Cell type enriched" "Detected in many" 33 "central nervous system macrophage: 213.3" "Group enriched" "Detected in many" 5 "Glioblastoma Multiforme (TCGA): 33.2;Kidney Renal Clear Cell Carcinoma (TCGA): 55.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "naive B-cell: 23.3" "Lineage enriched" "Detected in many" 5 "B-cells: 23.3" "Group enriched" "Detected in many" 8 "Leukemia: 40.5;lymphoma: 53.5;Myeloma: 32.2" "Adrenal gland - Macrophages, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Pituitary gland - Macrophages, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA005449, HPA075145" Enhanced Supported "Plasma membrane,Mid piece,Principal piece" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 12 "Plasma membrane" "Mid piece, Principal piece" "HPA005449: , HPA075145: " "unprognostic (1.66e-1)" "unprognostic (2.67e-1)" "unprognostic (2.25e-1)" "unprognostic (1.30e-1)" "unprognostic (2.19e-1)" "unprognostic (2.27e-1)" "unprognostic (2.66e-2)" "unprognostic (6.38e-2)" "unprognostic (7.38e-2)" "potential prognostic favorable (5.25e-4)" "unprognostic (4.50e-1)" "unprognostic (3.61e-1)" "unprognostic (2.66e-3)" "unprognostic (1.30e-1)" "unprognostic (2.01e-1)" "unprognostic (6.03e-2)" "unprognostic (1.08e-2)" "unprognostic (3.49e-1)" "unprognostic (5.42e-2)" "unprognostic (3.82e-1)" "unprognostic (3.62e-2)" "unprognostic (7.44e-2)" "unprognostic (9.17e-2)" "unprognostic (3.29e-3)" "unprognostic (2.65e-3)" "unprognostic (2.52e-1)" "unprognostic (2.78e-2)" "unprognostic (1.21e-1)" "unprognostic (2.18e-2)" SLC2A6 "GLUT6, GLUT9, HSA011372" ENSG00000160326 "Solute carrier family 2 member 6" Q9UGQ3 9 133471094-133479127 "Metabolic proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.6;lymphoid tissue: 13.5" "Cell type enhanced" "Detected in some" "Astrocytes: 9.7;Bergmann glia: 3.9;Brain excitatory neurons: 19.1;Brain inhibitory neurons: 16.1;Loop of henle epithelial cells: 4.0;monocytes: 5.7;Oligodendrocyte progenitor cells: 7.2;Oligodendrocytes: 6.8;Other brain neurons: 24.7;Papillary tip epithelial cells: 6.6;Renal collecting duct principal cells: 5.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 73.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042272, CAB046014" Uncertain NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 5: Spleen - Immune response" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 55: Lymphoma - Immune response" "Cluster 109: Neurons - Neuronal signaling" 1 "CAB046014: , HPA042272: " "unprognostic (2.01e-2)" "unprognostic (3.75e-1)" "unprognostic (5.13e-2)" "unprognostic (6.95e-3)" "unprognostic (2.26e-2)" "unprognostic (1.03e-1)" "unprognostic (1.54e-2)" "unprognostic (5.78e-2)" "unprognostic (5.20e-2)" "potential prognostic unfavorable (9.84e-9)" "unprognostic (2.40e-2)" "unprognostic (2.38e-1)" "unprognostic (1.46e-3)" "unprognostic (1.66e-3)" "unprognostic (7.85e-2)" "unprognostic (2.71e-1)" "unprognostic (4.15e-2)" "unprognostic (2.74e-1)" "unprognostic (9.34e-2)" "unprognostic (3.02e-2)" "unprognostic (3.97e-2)" "unprognostic (3.74e-3)" "unprognostic (5.09e-3)" "unprognostic (4.20e-2)" "unprognostic (3.00e-1)" "unprognostic (7.00e-2)" "unprognostic (5.53e-2)" "unprognostic (5.15e-2)" SLC2A7 GLUT7 ENSG00000197241 "Solute carrier family 2 member 7" Q6PXP3 1 9002973-9026423 "Metabolic proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 8 "intestine: 2.3" "Cell type enhanced" "Detected in some" "Enterocytes: 4.7;Epicardial cells: 2.3;Epididymal principal cells: 2.4;Granulosa cells: 5.7;Plasma cells: 5.9;Retinal horizontal cells: 2.0;Undifferentiated spermatogonia: 3.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA039931 Uncertain NA NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 34: Testis cancer - Unknown function" "Cluster 44: Plasma cells - Antibody production & secretion" "HPA039931: " SLC2A8 "GLUT8, GLUTX1" ENSG00000136856 "Solute carrier family 2 member 8" Q9NY64 9 127397138-127408424 "Metabolic proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 98.5;Decidual stromal cells: 166.5;Early spermatids: 151.7;Endometrial stromal cells: 77.7;Epididymal principal cells: 81.0;Hofbauer cells: 139.2;Late primary spermatocytes: 195.0;Late spermatids: 582.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "plasmacytoid DC: 76.1" "Lineage enriched" "Detected in all" 5 "dendritic cells: 76.1" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Spleen - Macrophages, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011935 Uncertain Approved Vesicles NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 67: Testis - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 32: Non-specific - Cell proliferation" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 25 Vesicles "HPA011935: " "unprognostic (5.58e-2)" "unprognostic (7.35e-2)" "unprognostic (2.03e-1)" "potential prognostic favorable (3.66e-5)" "unprognostic (2.75e-2)" "unprognostic (2.78e-2)" "unprognostic (3.50e-1)" "potential prognostic favorable (1.52e-5)" "unprognostic (1.94e-2)" "unprognostic (3.61e-1)" "potential prognostic favorable (1.50e-5)" "unprognostic (8.89e-2)" "potential prognostic favorable (5.47e-4)" "unprognostic (1.72e-1)" "unprognostic (2.66e-1)" "unprognostic (2.51e-1)" "unprognostic (5.09e-2)" "unprognostic (1.81e-1)" "unprognostic (7.26e-3)" "unprognostic (4.40e-1)" "unprognostic (4.37e-1)" "potential prognostic favorable (4.44e-5)" "unprognostic (2.40e-2)" "unprognostic (1.26e-1)" "unprognostic (4.31e-2)" "unprognostic (1.27e-1)" "unprognostic (1.72e-2)" "unprognostic (9.81e-2)" "unprognostic (7.68e-2)" "potential prognostic unfavorable (4.63e-4)" "unprognostic (2.60e-2)" SLC2A9 "Glut9, GLUTX, URATv1" ENSG00000109667 "Solute carrier family 2 member 9" Q9NRM0 4 9771153-10054936 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 27.3;liver: 20.0" "Cell type enriched" "Detected in many" 9 "Proximal tubule cells: 1694.5" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 129.3" "Cancer enhanced" "Detected in all" "Kidney Renal Papillary Cell Carcinoma (TCGA): 33.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 36.9;myeloid DC: 30.5" "Group enriched" "Detected in many" 30 "dendritic cells: 30.5;monocytes: 36.9" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 14.0;head and neck cancer: 11.5" "Adipose visceral - Macrophages, Breast - Breast myoepithelial cells, Kidney - Proximal tubular cells, Skin - Outer root sheath cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA066229, HPA075669" Enhanced NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 88: Proximal tubular cells - Transmembrane transport" 3 "HPA066229: , HPA075669: " "unprognostic (1.77e-1)" "unprognostic (1.80e-1)" "unprognostic (9.02e-2)" "unprognostic (6.68e-2)" "unprognostic (1.56e-2)" "unprognostic (4.89e-1)" "unprognostic (4.80e-3)" "unprognostic (1.40e-1)" "unprognostic (1.09e-2)" "unprognostic (4.23e-1)" "potential prognostic favorable (2.15e-11)" "unprognostic (1.75e-3)" "unprognostic (2.31e-3)" "unprognostic (1.09e-1)" "unprognostic (1.42e-2)" "unprognostic (3.08e-2)" "unprognostic (1.47e-1)" "unprognostic (1.57e-1)" "unprognostic (3.38e-2)" "potential prognostic unfavorable (4.29e-4)" "unprognostic (1.29e-1)" "unprognostic (2.52e-1)" "unprognostic (1.96e-1)" "unprognostic (3.52e-1)" "unprognostic (1.28e-2)" "unprognostic (1.51e-3)" "unprognostic (1.89e-1)" "unprognostic (6.72e-2)" "unprognostic (1.83e-2)" "potential prognostic unfavorable (2.60e-4)" "unprognostic (1.73e-1)" SLC30A1 "ZNT1, ZRC1" ENSG00000170385 "Solute carrier family 30 member 1" Q9Y6M5 1 211571568-211579161 "Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 80.5" "Cell type enhanced" "Detected in many" "Endometrial luminal cells: 77.1;Epididymal efferent duct absorptive cells: 76.9;Epididymal efferent duct ciliated cells: 98.2;Hepatocytes: 105.6" "Cell type enriched" "Detected in all" 6 "endothelial cell: 224.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 79.1" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015275, HPA049000" Uncertain Supported "Vesicles,Plasma membrane" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 47: Leukemia - Hemostasis" "Cluster 104: Brain endothelial cells - Blood brain barrier" 21 "Plasma membrane" Vesicles "HPA015275: , HPA049000: " "unprognostic (4.74e-2)" "unprognostic (2.27e-1)" "unprognostic (3.86e-2)" "potential prognostic unfavorable (1.48e-4)" "unprognostic (1.90e-1)" "unprognostic (6.39e-2)" "unprognostic (1.84e-1)" "unprognostic (4.15e-3)" "unprognostic (1.90e-1)" "unprognostic (1.85e-1)" "potential prognostic favorable (5.14e-6)" "unprognostic (1.97e-2)" "unprognostic (5.42e-2)" "unprognostic (4.78e-2)" "unprognostic (1.72e-2)" "unprognostic (1.28e-2)" "unprognostic (1.03e-2)" "unprognostic (4.28e-3)" "unprognostic (1.06e-1)" "unprognostic (7.70e-2)" "potential prognostic unfavorable (1.39e-4)" "potential prognostic unfavorable (2.22e-4)" "unprognostic (9.64e-2)" "unprognostic (1.16e-1)" "unprognostic (1.27e-1)" "unprognostic (1.49e-1)" "unprognostic (4.21e-1)" "unprognostic (1.50e-1)" "unprognostic (1.80e-1)" "unprognostic (2.51e-1)" "unprognostic (3.37e-2)" SLC30A10 "DKFZp547M236, ZnT-10, ZNT8, ZRC1" ENSG00000196660 "Solute carrier family 30 member 10" Q6XR72 1 219685427-219959018 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Transport, Zinc transport" "Disease variant, Dystonia, Neurodegeneration, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "intestine: 23.1;liver: 44.2" "Cell type enhanced" "Detected in many" "Astrocytes: 110.9;Bergmann glia: 133.3;Choroid plexus epithelial cells: 134.3;Colonocytes: 159.3;Early spermatids: 75.9;Enterocytes: 129.5;Hepatocytes: 237.2;Plasma cells: 218.5" "Cell type enriched" "Detected in all" 6 "pericyte: 1371.5" "Cancer enriched" "Detected in some" 17 "Liver Hepatocellular Carcinoma (TCGA): 18.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "liver cancer: 1.6" "Colon - Colon enterocytes, Liver - Hepatocytes, Pituitary gland - Gonadotropes, Skin - Sebaceous gland cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA064547 Enhanced NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 23: Choroid plexus - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 5 "HPA064547: " "unprognostic (2.01e-1)" "unprognostic (5.68e-3)" "unprognostic (2.09e-2)" "unprognostic (6.75e-2)" "unprognostic (1.82e-1)" SLC30A2 ZNT2 ENSG00000158014 "Solute carrier family 30 member 2" Q9BRI3 1 26037252-26046118 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Transport, Zinc transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "pancreas: 79.4" "Cell type enhanced" "Detected in some" "Breast lactating cells: 103.5;Cytotrophoblasts: 41.8;Endometrial glandular cells: 91.8;Endometrial luminal cells: 121.6;Epididymal efferent duct absorptive cells: 23.4;Pancreatic acinar cells: 37.8;Proximal tubule cells: 26.3;Syncytiotrophoblasts: 117.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 29.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Thyroid gland - Thyroid glandular cells" "Region enriched" "Detected in single" 5 "olfactory bulb: 1.2" "Not detected" "Not detected" HPA017979 Approved Vesicles NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 48: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 64 Vesicles "HPA017979: " "unprognostic (1.18e-1)" "unprognostic (5.06e-2)" "unprognostic (1.76e-1)" "unprognostic (9.33e-2)" "unprognostic (1.58e-1)" "unprognostic (1.05e-2)" "unprognostic (5.53e-2)" "unprognostic (2.61e-1)" "unprognostic (6.34e-2)" "unprognostic (8.51e-2)" "unprognostic (5.30e-2)" "unprognostic (2.60e-1)" "unprognostic (1.46e-1)" "unprognostic (2.86e-1)" "unprognostic (7.89e-2)" "potential prognostic unfavorable (2.98e-4)" "unprognostic (7.97e-2)" "unprognostic (1.83e-3)" "unprognostic (8.90e-2)" "unprognostic (2.77e-1)" "unprognostic (5.83e-2)" "unprognostic (7.77e-2)" "unprognostic (5.08e-2)" SLC30A3 ZNT3 ENSG00000115194 "Solute carrier family 30 member 3" Q99726 2 27253684-27275817 "Predicted membrane proteins, Transporters" "Antiport, Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 30.3;epididymis: 64.6;testis: 32.0" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 26.4;Cardiomyocytes: 134.0;Epididymal principal cells: 333.7;Late primary spermatocytes: 27.0;Late spermatids: 75.2;Sertoli cells: 63.2" "Cell type enhanced" "Detected in many" "deep-layer intratelencephalic: 49.4;hippocampal dentate gyrus: 96.1;upper-layer intratelencephalic: 61.7" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 4.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 6.9" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Heart muscle - Cardiomyocytes, Pituitary gland - Fibroblasts, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Testis - Sertoli cells" "Group enriched" "Detected in all" 4 "amygdala: 130.8;basal ganglia: 48.2;cerebral cortex: 110.9;hippocampal formation: 69.1;white matter: 34.7" "Group enriched" "Detected in many" 7 "amygdala: 24.3;cerebral cortex: 72.0;hippocampal formation: 56.1" "HPA060505, HPA067637, CAB079044" Enhanced Approved Approved Nucleoplasm,Nucleoli,Vesicles,Cytosol NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 32 Vesicles "Nucleoplasm, Nucleoli, Cytosol" "CAB079044: , HPA060505: , HPA067637: " "unprognostic (3.04e-1)" "unprognostic (1.25e-1)" "unprognostic (3.62e-1)" "unprognostic (1.77e-3)" "unprognostic (1.77e-1)" "unprognostic (6.06e-3)" "unprognostic (1.25e-1)" "unprognostic (2.88e-1)" "unprognostic (3.40e-2)" "unprognostic (2.43e-1)" SLC30A4 ZNT4 ENSG00000104154 "Solute carrier family 30 member 4" O14863 15 45479606-45522755 "Plasma proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "prostate: 37.4" "Cell type enriched" "Detected in many" 5 "Prostatic glandular cells: 746.6" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 16 "Prostate Adenocarcinoma (TCGA): 50.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in many" 9 "prostate cancer: 28.5" "Prostate - Prostate glandular cells, Spleen - Endothelial cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 33 "unprognostic (1.87e-2)" "unprognostic (3.28e-2)" "unprognostic (4.12e-1)" "unprognostic (5.27e-2)" "unprognostic (2.97e-1)" "unprognostic (1.11e-1)" "unprognostic (1.18e-1)" "unprognostic (3.03e-1)" "unprognostic (4.49e-2)" "unprognostic (1.28e-2)" "validated prognostic favorable (1.02e-6)" "validated prognostic favorable (9.25e-4)" "unprognostic (5.43e-2)" "unprognostic (9.54e-3)" "unprognostic (1.69e-1)" "unprognostic (3.09e-2)" "unprognostic (4.07e-2)" "unprognostic (2.13e-1)" "unprognostic (2.59e-2)" "unprognostic (4.62e-3)" "unprognostic (8.43e-2)" "unprognostic (9.32e-2)" "unprognostic (2.45e-2)" "unprognostic (5.47e-2)" "unprognostic (1.70e-1)" "unprognostic (3.90e-2)" "unprognostic (7.89e-2)" "unprognostic (1.46e-3)" "unprognostic (1.16e-2)" SLC30A5 "FLJ12496, FLJ12756, MGC5499, ZnT-5, ZNT5, ZNTL1, ZTL1" ENSG00000145740 "Solute carrier family 30 member 5" Q8TAD4 5 69093991-69131069 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Megakaryocyte progenitors: 188.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035373 Approved Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 8: Non-specific - Secretory pathway" 20 "Golgi apparatus" Nucleoplasm "HPA035373: " "unprognostic (7.86e-3)" "unprognostic (8.84e-2)" "unprognostic (1.03e-1)" "unprognostic (1.84e-1)" "unprognostic (2.33e-1)" "unprognostic (1.25e-1)" "unprognostic (9.17e-2)" "potential prognostic unfavorable (4.26e-5)" "unprognostic (1.11e-1)" "potential prognostic unfavorable (1.48e-5)" "potential prognostic favorable (9.42e-4)" "unprognostic (5.11e-2)" "unprognostic (4.33e-3)" "potential prognostic unfavorable (6.62e-6)" "unprognostic (4.57e-3)" "unprognostic (2.79e-2)" "unprognostic (8.52e-3)" "unprognostic (1.02e-1)" "unprognostic (2.45e-1)" "unprognostic (2.59e-1)" "unprognostic (2.55e-3)" "unprognostic (4.41e-2)" "unprognostic (1.79e-3)" "unprognostic (1.08e-1)" "unprognostic (4.74e-2)" "unprognostic (5.63e-3)" "unprognostic (1.82e-2)" "unprognostic (4.40e-2)" "unprognostic (8.23e-2)" "unprognostic (7.56e-2)" "unprognostic (2.15e-1)" SLC30A6 "FLJ31101, ZNT6" ENSG00000152683 "Solute carrier family 30 member 6" Q6NXT4 2 32165841-32224379 "Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055032, HPA057328" Uncertain Enhanced "Golgi apparatus" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 12 "Golgi apparatus" "HPA055032: , HPA057328: " "unprognostic (2.94e-1)" "unprognostic (3.70e-2)" "unprognostic (2.29e-1)" "unprognostic (2.14e-2)" "unprognostic (4.44e-2)" "unprognostic (1.77e-2)" "unprognostic (2.52e-1)" "unprognostic (2.97e-3)" "unprognostic (4.02e-1)" "unprognostic (4.82e-2)" "potential prognostic favorable (4.78e-4)" "unprognostic (3.43e-1)" "unprognostic (5.19e-3)" "validated prognostic unfavorable (5.98e-5)" "validated prognostic unfavorable (2.77e-4)" "unprognostic (5.97e-2)" "unprognostic (4.38e-2)" "unprognostic (2.98e-2)" "unprognostic (1.47e-1)" "unprognostic (1.02e-1)" "unprognostic (3.39e-2)" "unprognostic (7.69e-3)" "unprognostic (2.45e-2)" "unprognostic (1.57e-1)" "unprognostic (1.11e-2)" "unprognostic (5.26e-2)" "unprognostic (1.56e-1)" "unprognostic (1.13e-1)" "unprognostic (2.69e-1)" "unprognostic (5.57e-2)" "unprognostic (3.41e-1)" SLC30A7 "ZNT7, ZnTL2" ENSG00000162695 "Solute carrier family 30 member 7" Q8NEW0 1 100896076-100981757 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018034 Uncertain Supported "Golgi apparatus" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 70: Non-specific - Protein processing" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 37: Non-specific - mRNA processing" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 40 "Golgi apparatus" "HPA018034: " "unprognostic (3.03e-3)" "unprognostic (6.76e-2)" "unprognostic (3.62e-2)" "unprognostic (7.32e-2)" "unprognostic (5.83e-3)" "unprognostic (6.66e-2)" "unprognostic (2.22e-1)" "unprognostic (1.80e-2)" "unprognostic (2.09e-1)" "unprognostic (1.76e-2)" "potential prognostic favorable (3.63e-4)" "unprognostic (1.57e-2)" "unprognostic (6.46e-2)" "unprognostic (1.01e-3)" "unprognostic (1.93e-1)" "unprognostic (4.75e-3)" "unprognostic (5.49e-2)" "unprognostic (2.55e-1)" "unprognostic (7.05e-2)" "unprognostic (2.50e-2)" "unprognostic (1.95e-2)" "unprognostic (6.91e-3)" "unprognostic (3.94e-1)" "unprognostic (1.52e-1)" "unprognostic (2.40e-2)" "unprognostic (3.27e-1)" "unprognostic (1.06e-1)" "unprognostic (1.22e-1)" "unprognostic (1.95e-1)" "unprognostic (2.87e-2)" "unprognostic (1.81e-1)" SLC30A8 "ZnT-8, ZNT8" ENSG00000164756 "Solute carrier family 30 member 8" Q8IWU4 8 116950273-117176714 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Transport, Zinc transport" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "pancreas: 49.4" "Cell type enriched" "Detected in many" 5 "Pancreatic islet cells: 664.9" "Cell type enhanced" "Detected in many" "lower rhombic lip: 28.0" "Group enriched" "Detected in some" 28 "Breast Invasive Carcinoma (TCGA): 24.5;Pancreatic Adenocarcinoma (TCGA): 39.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "head and neck cancer: 18.5;Sarcoma: 16.7" "Kidney - Proximal tubular cells, Pancreas - Alpha cells, Pancreas - Beta cells" "Not detected" "Not detected" "Region enhanced" "Detected in some" "hippocampal formation: 5.5" "HPA065953, HPA076165" Enhanced Supported "Vesicles,Plasma membrane" NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 37: Neurons - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 66 "Vesicles, Plasma membrane" "HPA065953: , HPA076165: " "unprognostic (2.74e-2)" "unprognostic (1.64e-2)" "unprognostic (2.31e-1)" "unprognostic (5.42e-2)" "unprognostic (2.31e-1)" SLC30A9 "C4orf1, GAC63, HUEL, ZNT9" ENSG00000014824 "Solute carrier family 30 member 9" Q6PML9 4 41990502-42090461 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Transcription, Transcription regulation, Transport, Zinc transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004014 Approved Supported Mitochondria,Cytosol NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 72: Kidney - Transmembrane transport" "Cluster 14: Neurons - Synaptic function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 25 Mitochondria Cytosol "HPA004014: " "unprognostic (1.27e-1)" "unprognostic (2.27e-2)" "unprognostic (1.79e-1)" "unprognostic (1.82e-2)" "unprognostic (4.65e-3)" "unprognostic (1.91e-2)" "unprognostic (9.38e-2)" "unprognostic (1.86e-1)" "unprognostic (2.38e-1)" "unprognostic (3.06e-2)" "potential prognostic favorable (1.93e-7)" "unprognostic (1.35e-3)" "potential prognostic favorable (5.78e-4)" "unprognostic (7.73e-2)" "unprognostic (2.13e-1)" "unprognostic (3.34e-1)" "unprognostic (2.11e-1)" "unprognostic (4.61e-2)" "unprognostic (7.15e-2)" "unprognostic (1.38e-1)" "unprognostic (9.89e-3)" "unprognostic (6.99e-2)" "unprognostic (3.57e-1)" "unprognostic (7.62e-2)" "unprognostic (7.60e-2)" "unprognostic (1.95e-2)" "unprognostic (3.10e-2)" "unprognostic (2.30e-1)" "unprognostic (1.52e-1)" "unprognostic (6.24e-3)" "unprognostic (1.05e-2)" SLC31A1 "COPT1, CTR1, hCTR1" ENSG00000136868 "Solute carrier family 31 member 1" O15431 9 113221544-113264492 "Metabolic proteins, Predicted membrane proteins, Transporters" "Copper transport, Ion transport, Transport" "Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 100.5" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 234.0;Prostatic glandular cells: 138.4" "Cell type enhanced" "Detected in all" "endothelial cell: 111.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 20.9;intermediate monocyte: 26.8;myeloid DC: 16.3;neutrophil: 8.2;non-classical monocyte: 31.1" "Group enriched" "Detected in all" 4 "dendritic cells: 16.3;granulocytes: 8.2;monocytes: 31.1" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013810 Approved NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 44: Non-specific - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 46 "HPA013810: " "unprognostic (1.59e-1)" "unprognostic (1.35e-3)" "unprognostic (4.50e-2)" "unprognostic (2.19e-2)" "unprognostic (9.42e-2)" "unprognostic (1.69e-1)" "unprognostic (7.35e-2)" "unprognostic (2.28e-2)" "unprognostic (1.09e-1)" "unprognostic (1.23e-2)" "potential prognostic favorable (1.37e-7)" "unprognostic (2.73e-2)" "unprognostic (2.69e-2)" "unprognostic (2.45e-2)" "unprognostic (8.11e-2)" "unprognostic (1.94e-1)" "unprognostic (8.43e-2)" "unprognostic (4.33e-2)" "unprognostic (1.27e-1)" "unprognostic (9.42e-2)" "unprognostic (3.91e-1)" "unprognostic (3.25e-2)" "unprognostic (1.48e-1)" "unprognostic (2.73e-1)" "unprognostic (1.47e-1)" "unprognostic (8.27e-2)" "unprognostic (1.41e-1)" "unprognostic (5.30e-2)" "unprognostic (1.61e-2)" "unprognostic (6.65e-3)" "unprognostic (9.23e-3)" SLC31A2 "COPT2, CTR2, hCTR2" ENSG00000136867 "Solute carrier family 31 member 2" O15432 9 113150976-113164140 "Predicted membrane proteins, Transporters" "Copper transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 535.8;salivary gland: 385.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 119.5;Kupffer cells: 204.0;Lacrimal acinar cells: 143.1;Macrophages: 89.9;monocytes: 101.9;Neutrophils: 122.3;Oligodendrocytes: 163.6;Salivary acinar cells: 262.1;Salivary myoepithelial cells: 75.6" "Cell type enriched" "Detected in all" 4 "oligodendrocyte: 222.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 12 "classical monocyte: 225.9;intermediate monocyte: 331.5;myeloid DC: 134.5;neutrophil: 357.2;non-classical monocyte: 424.7" "Group enriched" "Detected in all" 46 "dendritic cells: 134.5;granulocytes: 357.2;monocytes: 424.7" "Cancer enhanced" "Detected in many" "head and neck cancer: 27.7" "Adrenal gland - Adrenal cortex cells, Colon - Macrophages, Lung - Macrophages, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Macrophages, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014861, CAB080265, CAB080267" Supported Approved "Nuclear speckles,Plasma membrane,Intermediate filaments" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 30: White matter - Myelination" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 10 "Plasma membrane" "Nuclear speckles, Intermediate filaments" "CAB080265: , CAB080267: , HPA014861: " "unprognostic (7.38e-2)" "unprognostic (9.57e-2)" "unprognostic (2.67e-2)" "unprognostic (1.48e-1)" "unprognostic (2.58e-1)" "unprognostic (9.71e-2)" "unprognostic (4.58e-2)" "unprognostic (1.82e-1)" "potential prognostic unfavorable (9.72e-4)" "unprognostic (1.94e-2)" "potential prognostic favorable (9.70e-6)" "unprognostic (1.95e-3)" "potential prognostic favorable (6.71e-4)" "unprognostic (3.25e-1)" "unprognostic (2.15e-2)" "unprognostic (1.32e-1)" "unprognostic (2.21e-1)" "unprognostic (1.06e-2)" "unprognostic (3.90e-2)" "unprognostic (2.23e-3)" "unprognostic (2.77e-1)" "unprognostic (1.02e-1)" "unprognostic (1.80e-1)" "unprognostic (1.40e-1)" "unprognostic (2.19e-2)" "unprognostic (2.97e-1)" "unprognostic (7.15e-2)" "unprognostic (1.15e-1)" "unprognostic (6.31e-2)" "unprognostic (5.21e-2)" "unprognostic (1.76e-1)" SLC32A1 "bA122O1.1, VGAT, VIAAT" ENSG00000101438 "Solute carrier family 32 member 1" Q9H598 20 38724486-38729372 "Metabolic proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Transport" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 44.4" "Group enriched" "Detected in some" 8 "Brain inhibitory neurons: 33.4;Other brain neurons: 28.2;pDCs: 28.1;Retinal amacrine cells: 55.4;Retinal horizontal cells: 32.1" "Group enriched" "Detected in many" 16 "cerebellar inhibitory: 47.7;CGE interneuron: 50.6;eccentric medium spiny neuron: 28.7;LAMP5-LHX6 and Chandelier: 54.1;medium spiny neuron: 21.5;MGE interneuron: 33.5;midbrain-derived inhibitory: 41.0;splatter: 19.4" "Cancer enhanced" "Detected in single" "Glioblastoma Multiforme (TCGA): 1.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pituitary gland - Thyrotropes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037156, HPA058859, HPA059985" Enhanced Supported Uncertain Cytosol NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 109: Neurons - Neuronal signaling" 2 Cytosol "CAB037156: , HPA058859: , HPA059985: " "unprognostic (1.55e-2)" "unprognostic (5.56e-2)" SLC33A1 "ACATN, AT-1, AT1, SPG42" ENSG00000169359 "Solute carrier family 33 member 1" O00400 3 155821024-155854456 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Cataract, Deafness, Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 30.2;Bergmann glia: 32.5;Brain excitatory neurons: 29.0;Brain inhibitory neurons: 27.3;Choroid plexus epithelial cells: 41.1;Ependymal cells: 23.4;Late spermatids: 11.3;Microglia: 37.3;Oligodendrocyte progenitor cells: 26.1;Oligodendrocytes: 36.1;Other brain neurons: 28.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042430 Uncertain Approved Vesicles,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 63: Non-specific - Protein processing" "Cluster 22: Non-specific - Basic cellular functions" 16 "Vesicles, Cytosol" "HPA042430: " "unprognostic (1.81e-1)" "unprognostic (1.37e-2)" "unprognostic (1.72e-2)" "unprognostic (1.66e-2)" "unprognostic (6.53e-2)" "unprognostic (1.43e-1)" "unprognostic (2.86e-2)" "potential prognostic unfavorable (6.06e-4)" "unprognostic (1.91e-1)" "unprognostic (5.19e-3)" "potential prognostic favorable (8.08e-7)" "unprognostic (1.16e-2)" "unprognostic (1.47e-1)" "unprognostic (1.43e-1)" "unprognostic (1.53e-1)" "unprognostic (4.83e-2)" "unprognostic (4.88e-2)" "unprognostic (1.22e-1)" "unprognostic (1.77e-2)" "unprognostic (8.36e-3)" "unprognostic (4.22e-3)" "unprognostic (1.38e-3)" "unprognostic (6.83e-2)" "unprognostic (1.27e-1)" "unprognostic (7.33e-2)" "unprognostic (5.83e-2)" "unprognostic (4.35e-2)" "unprognostic (7.23e-2)" "unprognostic (1.97e-1)" "unprognostic (1.52e-1)" "unprognostic (6.85e-2)" SLC34A1 "NAPI-3, NPT2, NPTIIa, SLC11, SLC17A2" ENSG00000131183 "Solute carrier family 34 member 1" Q06495 5 177379235-177398848 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant, Osteoporosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 55 "kidney: 145.2" "Cell type enriched" "Detected in some" 25 "Proximal tubule cells: 181.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "Kidney Renal Clear Cell Carcinoma (TCGA): 3.9;Kidney Renal Papillary Cell Carcinoma (TCGA): 3.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA051255, HPA077175" Approved Approved "Nucleoplasm,Nuclear speckles,Plasma membrane,Mitotic spindle,Cytosol" Yes NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 47: Leukemia - Hemostasis" "Cluster 88: Proximal tubular cells - Transmembrane transport" 1 "Nuclear speckles, Plasma membrane" "Nucleoplasm, Mitotic spindle, Cytosol" "HPA051255: , HPA077175: " "potential prognostic favorable (1.78e-6)" "unprognostic (1.13e-3)" "unprognostic (1.23e-1)" SLC34A2 NAPI-3B ENSG00000157765 "Solute carrier family 34 member 2" O95436 4 25648011-25678748 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "lung: 709.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 867.2;Alveolar cells type 2: 1909.3;Breast lactating cells: 291.0;Endometrial glandular cells: 419.7;Endometrial secretory cells: 444.3;Respiratory ciliated cells: 218.0;Transitional alveolar cells: 1120.7" "Cell type enriched" "Detected in single" 19 "choroid plexus epithelial cell: 8.7" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 764.9;Thyroid Carcinoma (TCGA): 986.8" "Group enriched" "Detected in many" 6 "cerebellum: 5.4;choroid plexus: 15.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 53.2;ovarian cancer: 115.1;pancreatic cancer: 54.6;Uterine cancer: 52.8" "Kidney - Macrophages, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA037989, HPA066474" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 13: Lung - Secretion" "Cluster 5: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 81: Alveolar cells - Lung function" 13 "Plasma membrane" "Nucleoplasm, Cytosol" "HPA037989: , HPA066474: " "unprognostic (1.01e-2)" "unprognostic (5.82e-2)" "unprognostic (1.21e-1)" "unprognostic (1.64e-3)" "unprognostic (2.55e-1)" "unprognostic (5.37e-2)" "unprognostic (1.79e-1)" "unprognostic (3.23e-3)" "unprognostic (2.50e-1)" "potential prognostic favorable (1.65e-6)" "unprognostic (2.50e-2)" "unprognostic (1.22e-2)" "potential prognostic favorable (1.82e-4)" "unprognostic (6.89e-2)" "unprognostic (1.63e-3)" "unprognostic (1.05e-1)" "unprognostic (4.29e-3)" "unprognostic (1.16e-2)" "unprognostic (2.91e-2)" "unprognostic (6.27e-2)" "unprognostic (9.30e-2)" "unprognostic (1.60e-1)" "unprognostic (1.21e-1)" "unprognostic (1.61e-2)" "unprognostic (1.15e-2)" SLC34A3 "FLJ38680, NPTIIc" ENSG00000198569 "Solute carrier family 34 member 3" Q8N130 9 137230757-137236555 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 9.1;kidney: 14.3" "Cell type enhanced" "Detected in some" "Enterocytes: 80.2;Esophageal apical cells: 15.1;Esophageal suprabasal cells: 5.6;Proximal tubule cells: 23.9" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Pituitary gland - Gonadotropes" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA023776 Enhanced NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 39: Astrocytes - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 1: Enterocytes - Absorption and Digestion" 4 "HPA023776: " "unprognostic (4.15e-1)" "unprognostic (5.72e-2)" "unprognostic (1.00e-2)" "unprognostic (8.43e-2)" "unprognostic (5.05e-2)" SLC35A1 "CMPST, hCST" ENSG00000164414 "Solute carrier family 35 member A1" P78382 6 87470623-87512336 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Sugar transport, Transport" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Goblet cells: 79.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 31: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 70: Intestinal goblet cells - Mucin production" 27 "unprognostic (1.62e-3)" "unprognostic (2.04e-2)" "unprognostic (1.01e-1)" "unprognostic (1.66e-3)" "unprognostic (8.80e-2)" "unprognostic (7.57e-2)" "unprognostic (2.47e-1)" "unprognostic (2.91e-1)" "unprognostic (1.26e-2)" "unprognostic (6.55e-3)" "unprognostic (7.78e-3)" "potential prognostic favorable (7.43e-4)" "unprognostic (8.87e-2)" "unprognostic (2.94e-1)" "unprognostic (1.37e-1)" "unprognostic (5.16e-3)" "unprognostic (2.09e-1)" "unprognostic (7.00e-3)" "unprognostic (4.31e-1)" "unprognostic (2.54e-2)" "unprognostic (1.17e-1)" "unprognostic (5.53e-2)" "unprognostic (2.11e-1)" "unprognostic (1.28e-1)" "unprognostic (1.06e-1)" "unprognostic (3.50e-3)" "potential prognostic unfavorable (3.54e-4)" "unprognostic (1.80e-1)" "unprognostic (1.84e-1)" "unprognostic (1.57e-1)" "unprognostic (6.91e-2)" SLC35A2 "UGALT, UGAT, UGT, UGT1, UGT2, UGTL" ENSG00000102100 "Solute carrier family 35 member A2" P78381 X 48903180-48911958 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Sugar transport, Transport" "Congenital disorder of glycosylation, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 123.2;Syncytiotrophoblasts: 59.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036087 Approved Supported "Golgi apparatus" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 60: Stomach - Digestion" "Cluster 21: Non-specific - Metabolism" "Cluster 36: Non-specific - mRNA processing" "Cluster 4: Breast lactating luminal cells - Lactation" 3 "Golgi apparatus" "HPA036087: " "unprognostic (3.73e-2)" "potential prognostic unfavorable (1.15e-6)" "unprognostic (1.05e-1)" "unprognostic (2.27e-2)" "unprognostic (8.89e-2)" "unprognostic (2.10e-2)" "unprognostic (2.89e-2)" "unprognostic (6.53e-3)" "unprognostic (5.07e-2)" "unprognostic (9.33e-2)" "unprognostic (8.36e-3)" "potential prognostic unfavorable (1.01e-5)" "unprognostic (3.59e-2)" "validated prognostic unfavorable (5.22e-4)" "validated prognostic unfavorable (1.74e-4)" "unprognostic (1.78e-3)" "unprognostic (5.04e-2)" "unprognostic (2.81e-1)" "unprognostic (1.15e-2)" "unprognostic (2.04e-1)" "unprognostic (4.01e-2)" "unprognostic (1.07e-2)" "unprognostic (1.54e-1)" "unprognostic (8.14e-2)" "unprognostic (2.95e-2)" "unprognostic (2.42e-1)" "unprognostic (4.55e-1)" "unprognostic (8.60e-3)" "unprognostic (1.36e-1)" "unprognostic (4.15e-2)" "unprognostic (1.64e-2)" SLC35A3 ENSG00000117620 "Solute carrier family 35 member A3" Q9Y2D2 1 99969351-100035634 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Sugar transport, Transport" "Autism spectrum disorder, Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 5.2;Cardiomyocytes: 19.6;Megakaryocytes: 12.4;Respiratory deuterosomal cells: 3.1" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in all" 4 "Gallbladder cancer: 118.3" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015253 Uncertain NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 77: Intestine - Digestion" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 37: Non-specific - mRNA processing" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" "HPA015253: " "unprognostic (2.41e-1)" "unprognostic (1.01e-2)" "unprognostic (2.84e-1)" "unprognostic (1.18e-1)" "unprognostic (1.60e-3)" "unprognostic (1.70e-3)" "unprognostic (2.98e-1)" "unprognostic (2.88e-1)" "unprognostic (1.33e-1)" "unprognostic (1.10e-1)" "validated prognostic favorable (1.07e-6)" "validated prognostic favorable (2.81e-4)" "unprognostic (9.29e-2)" "unprognostic (5.26e-2)" "unprognostic (6.86e-2)" "unprognostic (2.05e-2)" "unprognostic (2.47e-2)" "unprognostic (8.55e-3)" "unprognostic (2.18e-2)" "unprognostic (2.80e-1)" "unprognostic (1.88e-3)" "unprognostic (5.89e-3)" "unprognostic (3.94e-2)" "unprognostic (1.69e-1)" "unprognostic (3.86e-3)" "unprognostic (1.02e-2)" "unprognostic (1.78e-2)" "unprognostic (1.23e-2)" "unprognostic (9.11e-2)" "unprognostic (6.71e-2)" "unprognostic (1.05e-1)" SLC35A4 ENSG00000176087 "Solute carrier family 35 member A4" "L0R6Q1, Q96G79" 5 140564446-140569100 "Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 251.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074521 Uncertain "Endoplasmic reticulum,Centrosome" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 47: Endothelial cells - Vasculature" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 23 "Endoplasmic reticulum, Centrosome" "HPA074521: " "unprognostic (2.56e-3)" "unprognostic (6.44e-3)" "unprognostic (4.62e-3)" "unprognostic (3.98e-1)" "unprognostic (2.01e-1)" "unprognostic (1.33e-1)" "unprognostic (1.23e-1)" "unprognostic (4.31e-3)" "unprognostic (3.12e-2)" "unprognostic (7.75e-3)" "potential prognostic favorable (2.42e-7)" "unprognostic (6.15e-3)" "unprognostic (2.26e-3)" "potential prognostic unfavorable (9.26e-4)" "unprognostic (3.60e-3)" "unprognostic (1.20e-1)" "unprognostic (4.11e-2)" "unprognostic (1.91e-2)" "unprognostic (1.64e-1)" "unprognostic (1.71e-2)" "unprognostic (5.94e-2)" "unprognostic (8.50e-2)" "unprognostic (5.80e-2)" "unprognostic (1.15e-1)" "unprognostic (6.45e-2)" "unprognostic (1.52e-2)" "unprognostic (2.67e-1)" "unprognostic (6.56e-2)" "unprognostic (2.14e-1)" "potential prognostic unfavorable (6.77e-4)" "unprognostic (2.89e-1)" SLC35A5 FLJ20730 ENSG00000138459 "Solute carrier family 35 member A5" Q9BS91 3 112561709-112585579 "Predicted membrane proteins, Transporters" "Antiport, Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Early spermatids: 287.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035519, HPA057964" Uncertain Approved "Golgi apparatus" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 63: Non-specific - Protein processing" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 9 "Golgi apparatus" "HPA035519: , HPA057964: " "unprognostic (8.79e-3)" "unprognostic (6.82e-3)" "unprognostic (7.64e-2)" "unprognostic (1.96e-2)" "unprognostic (3.49e-1)" "unprognostic (4.48e-2)" "unprognostic (3.69e-1)" "unprognostic (2.06e-3)" "unprognostic (2.51e-2)" "potential prognostic unfavorable (9.25e-5)" "potential prognostic favorable (7.81e-9)" "unprognostic (6.66e-3)" "potential prognostic favorable (9.13e-4)" "unprognostic (3.19e-2)" "unprognostic (2.20e-1)" "unprognostic (1.55e-1)" "unprognostic (2.33e-1)" "unprognostic (2.62e-1)" "unprognostic (3.55e-1)" "unprognostic (1.39e-1)" "unprognostic (1.93e-2)" "unprognostic (9.47e-3)" "unprognostic (1.52e-1)" "unprognostic (1.70e-1)" "unprognostic (3.00e-2)" "unprognostic (2.72e-1)" "unprognostic (3.06e-2)" "unprognostic (6.21e-2)" "unprognostic (3.58e-1)" "unprognostic (2.77e-1)" "unprognostic (1.96e-1)" SLC35B1 "AXER, UGTREL1" ENSG00000121073 "Solute carrier family 35 member B1" P78383 17 49700934-49709014 "Essential proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 129.1;Epididymal principal cells: 156.4;Extravillous trophoblasts: 157.8;Plasma cells: 139.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048655, HPA057418" Approved Supported "Endoplasmic reticulum,Vesicles" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 27: Breast cancer - Unknown function" "Cluster 8: Non-specific - Secretory pathway" 21 "Endoplasmic reticulum" Vesicles "HPA048655: , HPA057418: " "unprognostic (1.36e-2)" "unprognostic (1.81e-2)" "unprognostic (8.88e-2)" "unprognostic (3.52e-2)" "potential prognostic favorable (1.92e-5)" "unprognostic (8.84e-2)" "unprognostic (1.28e-1)" "unprognostic (4.62e-2)" "unprognostic (9.30e-2)" "potential prognostic unfavorable (1.52e-4)" "potential prognostic favorable (3.05e-4)" "unprognostic (1.19e-1)" "unprognostic (3.26e-1)" "unprognostic (1.17e-2)" "potential prognostic unfavorable (8.05e-4)" "unprognostic (4.71e-2)" "unprognostic (9.22e-2)" "unprognostic (1.55e-1)" "unprognostic (1.97e-2)" "unprognostic (1.08e-1)" "unprognostic (1.58e-1)" "unprognostic (7.33e-2)" "unprognostic (1.14e-2)" "unprognostic (1.46e-1)" "unprognostic (1.02e-1)" "unprognostic (8.13e-2)" "unprognostic (2.77e-1)" "unprognostic (4.40e-2)" "unprognostic (7.72e-2)" "unprognostic (3.04e-1)" "unprognostic (2.65e-1)" SLC35B2 UGTrel4 ENSG00000157593 "Solute carrier family 35 member B2" Q8TB61 6 44254096-44257890 "Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Transport" Leukodystrophy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 68.7;Differentiating spermatogonia: 70.2;Melanocytes: 84.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029638 Approved Approved Vesicles NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 70: Non-specific - Protein processing" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 61: Schwann cells & Melanocytes - Mixed function" 14 Vesicles "HPA029638: " "unprognostic (1.01e-1)" "unprognostic (1.25e-3)" "unprognostic (1.18e-1)" "potential prognostic unfavorable (2.01e-4)" "unprognostic (3.82e-1)" "unprognostic (4.70e-2)" "unprognostic (4.77e-2)" "unprognostic (2.68e-1)" "unprognostic (3.94e-3)" "unprognostic (1.55e-1)" "unprognostic (5.83e-2)" "unprognostic (6.24e-2)" "unprognostic (8.38e-2)" "validated prognostic unfavorable (2.61e-5)" "validated prognostic unfavorable (9.89e-5)" "unprognostic (3.05e-2)" "unprognostic (1.51e-1)" "unprognostic (1.12e-1)" "unprognostic (2.28e-1)" "unprognostic (1.09e-2)" "unprognostic (1.02e-1)" "unprognostic (2.80e-2)" "unprognostic (1.88e-1)" "unprognostic (3.60e-2)" "unprognostic (3.87e-2)" "unprognostic (2.57e-1)" "unprognostic (2.98e-1)" "unprognostic (5.51e-2)" "unprognostic (5.19e-1)" "unprognostic (7.09e-2)" "unprognostic (1.06e-1)" SLC35B3 "C6orf196, CGI-19, dJ453H5.1, PAPST2" ENSG00000124786 "Solute carrier family 35 member B3" Q9H1N7 6 8411435-8435561 "Predicted membrane proteins, Transporters" "Antiport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 138.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054661, HPA057801" Approved NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 22: Epididymis - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" "HPA054661: , HPA057801: " "unprognostic (1.46e-2)" "unprognostic (1.16e-1)" "unprognostic (2.53e-1)" "unprognostic (5.65e-2)" "unprognostic (4.33e-2)" "unprognostic (8.19e-2)" "unprognostic (1.19e-1)" "unprognostic (3.97e-1)" "unprognostic (1.25e-1)" "unprognostic (8.28e-2)" "potential prognostic favorable (5.28e-4)" "unprognostic (1.38e-1)" "unprognostic (1.94e-1)" "unprognostic (3.75e-2)" "unprognostic (2.87e-2)" "unprognostic (6.77e-2)" "unprognostic (3.42e-1)" "unprognostic (2.23e-3)" "unprognostic (4.00e-2)" "unprognostic (2.31e-1)" "unprognostic (6.39e-3)" "unprognostic (3.26e-2)" "unprognostic (2.34e-1)" "unprognostic (2.14e-1)" "unprognostic (9.68e-3)" "unprognostic (2.85e-2)" "unprognostic (5.75e-2)" "unprognostic (2.08e-1)" "unprognostic (8.07e-2)" "potential prognostic unfavorable (2.36e-4)" "unprognostic (4.49e-2)" SLC35B4 "FLJ14697, YEA4" ENSG00000205060 "Solute carrier family 35 member B4" Q969S0 7 134289332-134316930 "Metabolic proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 140.1;Distal convoluted tubule cells: 150.0;Migrating cytotrophoblasts: 93.1;Renal connecting tubule cells: 92.9;Syncytiotrophoblasts: 122.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049779 Approved NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 36: Brain & Liver - Signaling" "Cluster 1: Neurons - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 25 "HPA049779: " "unprognostic (3.29e-2)" "unprognostic (1.68e-1)" "unprognostic (9.35e-2)" "unprognostic (2.62e-2)" "unprognostic (9.95e-2)" "unprognostic (3.00e-3)" "unprognostic (5.45e-3)" "unprognostic (3.13e-2)" "unprognostic (6.50e-2)" "unprognostic (9.29e-2)" "potential prognostic favorable (1.74e-5)" "unprognostic (1.26e-2)" "unprognostic (1.04e-1)" "unprognostic (1.10e-2)" "unprognostic (2.79e-2)" "unprognostic (4.00e-2)" "unprognostic (4.12e-2)" "unprognostic (1.07e-1)" "unprognostic (1.41e-1)" "unprognostic (1.97e-1)" "unprognostic (3.22e-1)" "unprognostic (7.89e-2)" "unprognostic (1.39e-1)" "unprognostic (1.61e-1)" "unprognostic (2.32e-1)" "unprognostic (2.31e-2)" "unprognostic (2.27e-1)" "unprognostic (1.30e-1)" "unprognostic (2.00e-1)" "unprognostic (8.10e-2)" "unprognostic (1.59e-2)" SLC35C1 "FLJ11320, FUCT1" ENSG00000181830 "Solute carrier family 35 member C1" Q96A29 11 45804072-45813016 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 92.4" "Cell type enriched" "Detected in many" 4 "Esophageal apical cells: 293.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Minor Salivary Gland - Minor salivary glandular cells, Skin - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064001 Enhanced Supported "Golgi apparatus" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 84: Apical squamous epithelium - Cornification" 5 "Golgi apparatus" "HPA064001: " "unprognostic (4.98e-2)" "potential prognostic unfavorable (3.55e-4)" "unprognostic (2.41e-1)" "unprognostic (4.68e-3)" "unprognostic (1.24e-1)" "unprognostic (2.39e-2)" "unprognostic (3.29e-2)" "potential prognostic unfavorable (3.99e-4)" "unprognostic (1.10e-1)" "unprognostic (1.59e-2)" "potential prognostic favorable (1.82e-4)" "unprognostic (1.61e-2)" "unprognostic (8.00e-3)" "unprognostic (2.89e-2)" "unprognostic (3.42e-2)" "unprognostic (1.51e-2)" "unprognostic (1.63e-3)" "unprognostic (7.17e-3)" "unprognostic (9.46e-3)" "unprognostic (1.82e-1)" "unprognostic (2.09e-1)" "unprognostic (1.73e-2)" "unprognostic (1.56e-1)" "unprognostic (1.41e-1)" "unprognostic (1.43e-1)" "unprognostic (3.16e-3)" "unprognostic (4.10e-1)" "unprognostic (2.41e-2)" "unprognostic (8.84e-2)" "unprognostic (3.52e-2)" "unprognostic (2.77e-2)" SLC35C2 "bA394O2.1, C20orf5, CGI-15, OVCOV1" ENSG00000080189 "Solute carrier family 35 member C2" Q9NQQ7 20 46345980-46364458 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 144.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Breast - Breast glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027011 Approved Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 70: Non-specific - Protein processing" "Cluster 19: Astrocytes - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 6 "Golgi apparatus" Nucleoplasm "HPA027011: " "unprognostic (1.97e-2)" "potential prognostic unfavorable (6.26e-4)" "unprognostic (2.26e-1)" "unprognostic (1.91e-2)" "unprognostic (9.55e-2)" "unprognostic (1.34e-1)" "unprognostic (2.86e-3)" "unprognostic (4.39e-1)" "unprognostic (7.12e-2)" "unprognostic (1.64e-1)" "potential prognostic unfavorable (7.39e-5)" "unprognostic (1.34e-2)" "unprognostic (1.04e-2)" "validated prognostic unfavorable (3.75e-5)" "validated prognostic unfavorable (2.66e-4)" "unprognostic (9.66e-2)" "unprognostic (1.07e-1)" "unprognostic (4.01e-2)" "unprognostic (8.60e-2)" "unprognostic (5.28e-2)" "unprognostic (6.60e-2)" "unprognostic (1.36e-1)" "unprognostic (1.06e-1)" "unprognostic (3.39e-1)" "unprognostic (7.31e-3)" "unprognostic (2.54e-2)" "unprognostic (3.94e-1)" "unprognostic (1.60e-1)" "unprognostic (3.46e-1)" "unprognostic (1.66e-1)" "unprognostic (1.56e-1)" SLC35D1 "KIAA0260, UGTREL7" ENSG00000116704 "Solute carrier family 35 member D1" Q9NTN3 1 66999350-67054148 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 69.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 171.1;Pituicytes/FSCs: 166.0;Thymocytes: 169.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 8.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" "unprognostic (4.52e-3)" "unprognostic (8.42e-2)" "unprognostic (2.33e-1)" "unprognostic (1.60e-3)" "unprognostic (6.98e-3)" "unprognostic (3.80e-2)" "unprognostic (3.38e-1)" "unprognostic (2.85e-1)" "unprognostic (3.07e-2)" "unprognostic (1.12e-3)" "potential prognostic favorable (4.99e-4)" "unprognostic (1.82e-2)" "unprognostic (3.73e-2)" "unprognostic (1.06e-1)" "unprognostic (1.96e-1)" "unprognostic (5.00e-3)" "unprognostic (9.58e-2)" "unprognostic (5.44e-2)" "unprognostic (4.04e-1)" "unprognostic (1.31e-1)" "unprognostic (1.75e-2)" "unprognostic (2.04e-2)" "unprognostic (2.64e-2)" "unprognostic (1.36e-1)" "unprognostic (5.97e-2)" "unprognostic (2.15e-2)" "unprognostic (4.29e-3)" "unprognostic (2.87e-1)" "unprognostic (1.38e-1)" "unprognostic (2.89e-3)" "potential prognostic unfavorable (3.33e-4)" SLC35D2 "SQV7L, UGTrel8" ENSG00000130958 "Solute carrier family 35 member D2" Q76EJ3 9 96313444-96383711 "Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 52.4;Microglia: 67.2;Oligodendrocytes: 144.2;Proximal tubule cells: 61.9" "Cell type enhanced" "Detected in many" "oligodendrocyte: 190.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Skin - Endothelial cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA064047 Approved Supported "Golgi apparatus" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 77: Intestine - Digestion" "Cluster 11: White matter - Signal transduction" "Cluster 18: Liver cancer - Metabolism" "Cluster 80: Oligodendrocytes - Myelination" "Golgi apparatus" "HPA064047: " "unprognostic (2.30e-1)" "unprognostic (5.86e-2)" "unprognostic (7.70e-2)" "unprognostic (2.82e-1)" "unprognostic (2.24e-2)" "unprognostic (1.60e-1)" "unprognostic (1.85e-1)" "unprognostic (1.29e-1)" "unprognostic (8.77e-3)" "unprognostic (1.51e-1)" "potential prognostic favorable (3.48e-9)" "unprognostic (1.80e-3)" "unprognostic (7.06e-2)" "validated prognostic unfavorable (6.16e-4)" "validated prognostic unfavorable (4.30e-4)" "unprognostic (1.91e-1)" "unprognostic (3.86e-1)" "unprognostic (1.46e-2)" "unprognostic (4.35e-2)" "unprognostic (2.08e-1)" "unprognostic (4.38e-1)" "unprognostic (1.73e-1)" "unprognostic (4.82e-2)" "unprognostic (1.95e-1)" "unprognostic (4.05e-1)" "unprognostic (7.50e-3)" "unprognostic (1.65e-1)" "unprognostic (5.62e-2)" "unprognostic (3.58e-1)" "unprognostic (2.30e-3)" "unprognostic (9.72e-2)" SLC35D3 FRCL1 ENSG00000182747 "Solute carrier family 35 member D3" Q5M8T2 6 136922301-136925660 "Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "brain: 5.7" "Group enriched" "Detected in some" 7 "Megakaryocytes: 49.5;Platelets: 18.4" "Group enriched" "Detected in some" 4 "eccentric medium spiny neuron: 7.4;medium spiny neuron: 3.9;thalamic excitatory: 4.2" "Group enriched" "Detected in some" 4 "Colon Adenocarcinoma (TCGA): 3.9;Rectum Adenocarcinoma (TCGA): 4.7;Stomach Adenocarcinoma (TCGA): 1.4" "Group enriched" "Detected in many" 7 "basal ganglia: 7.9;hypothalamus: 12.5;midbrain: 4.7;thalamus: 12.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 2.8;Gastric cancer: 3.5;lung cancer: 3.3" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Beta cells, Stomach - Gastric enteroendocrine cells" "Group enriched" "Detected in many" 5 "basal ganglia: 29.6;olfactory bulb: 8.5" "Region enriched" "Detected in many" 6 "basal ganglia: 26.5" "HPA030431, HPA067497" Uncertain Approved "Centriolar satellite" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 47: Platelets - Hemostasis" 3 "Centriolar satellite" "HPA030431: , HPA067497: " "unprognostic (2.16e-1)" "unprognostic (1.75e-2)" "unprognostic (1.54e-2)" "unprognostic (2.06e-2)" "unprognostic (6.90e-2)" SLC35E1 FLJ14251 ENSG00000127526 "Solute carrier family 35 member E1" Q96K37 19 16549831-16572415 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Innate lymphoid cells: 5.4;Platelets: 9.8;Prostatic glandular cells: 5.1" "Low cell type specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016570, HPA062214" Approved Enhanced "Golgi apparatus" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 24: Non-specific - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 18 "Golgi apparatus" "HPA016570: , HPA062214: " "unprognostic (5.09e-3)" "unprognostic (3.99e-2)" "unprognostic (3.21e-3)" "unprognostic (1.57e-1)" "unprognostic (3.64e-1)" "unprognostic (3.88e-2)" "unprognostic (2.91e-1)" "unprognostic (2.09e-2)" "unprognostic (9.11e-2)" "unprognostic (2.63e-2)" "potential prognostic favorable (5.93e-4)" "unprognostic (1.24e-1)" "unprognostic (2.06e-1)" "unprognostic (1.58e-2)" "unprognostic (4.72e-3)" "unprognostic (1.58e-1)" "unprognostic (1.25e-2)" "unprognostic (7.59e-2)" "unprognostic (2.09e-2)" "unprognostic (1.65e-2)" "unprognostic (1.91e-3)" "unprognostic (8.97e-2)" "potential prognostic unfavorable (6.32e-4)" "unprognostic (1.96e-1)" "unprognostic (1.46e-2)" "unprognostic (2.15e-1)" "unprognostic (2.08e-1)" "unprognostic (5.23e-2)" "unprognostic (1.80e-1)" "unprognostic (2.42e-2)" "unprognostic (1.04e-1)" SLC35E2B ENSG00000189339 "Solute carrier family 35 member E2B" P0CK96 1 1659529-1692795 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Corticotrophs: 79.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045641, HPA062711" Uncertain Approved Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 64: Non-specific - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 7: Non-specific - Transcription" 1 Nucleoplasm "HPA045641: , HPA062711: " "unprognostic (2.09e-3)" "unprognostic (1.85e-1)" "unprognostic (3.60e-2)" "unprognostic (1.06e-1)" "unprognostic (1.51e-1)" "unprognostic (3.30e-1)" "unprognostic (3.61e-2)" "potential prognostic favorable (2.72e-4)" "unprognostic (1.57e-3)" "unprognostic (4.14e-2)" "unprognostic (3.32e-2)" "potential prognostic favorable (4.46e-4)" "unprognostic (1.01e-2)" "unprognostic (8.41e-2)" "unprognostic (5.61e-2)" "unprognostic (1.32e-1)" "unprognostic (1.26e-1)" "unprognostic (1.26e-1)" "unprognostic (6.34e-2)" "unprognostic (5.88e-2)" "unprognostic (3.11e-3)" "unprognostic (5.08e-2)" "unprognostic (2.31e-1)" "unprognostic (8.06e-2)" "unprognostic (9.21e-3)" "unprognostic (1.11e-1)" "unprognostic (1.25e-1)" "unprognostic (8.69e-2)" "unprognostic (3.44e-1)" "unprognostic (9.65e-2)" SLC35E3 BLOV1 ENSG00000175782 "Solute carrier family 35 member E3" Q7Z769 12 68746125-68793964 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Neutrophils: 198.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in some" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049403 Uncertain NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 48: Non-specific - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 24: Neutrophils - Innate immunity signal integration" 22 "HPA049403: " "unprognostic (2.52e-2)" "unprognostic (3.60e-1)" "unprognostic (2.15e-1)" "unprognostic (6.45e-2)" "unprognostic (4.58e-2)" "unprognostic (9.27e-2)" "unprognostic (4.19e-2)" "potential prognostic unfavorable (4.24e-5)" "unprognostic (3.36e-2)" "potential prognostic unfavorable (2.16e-5)" "unprognostic (3.71e-1)" "unprognostic (1.08e-1)" "unprognostic (2.92e-3)" "unprognostic (2.79e-2)" "unprognostic (2.52e-3)" "unprognostic (1.10e-3)" "unprognostic (1.40e-1)" "unprognostic (1.34e-1)" "unprognostic (2.42e-1)" SLC35E4 ENSG00000100036 "Solute carrier family 35 member E4" Q6ICL7 22 30635781-30669016 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 21.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 34.0;Myonuclei: 37.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Liver - Vascular endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049558 Approved Approved Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 67: Testis - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 12 Cytosol "HPA049558: " "potential prognostic unfavorable (2.32e-4)" "unprognostic (2.02e-1)" "unprognostic (2.50e-2)" "unprognostic (1.84e-1)" "unprognostic (1.95e-2)" "unprognostic (3.53e-2)" "unprognostic (2.76e-1)" "unprognostic (9.77e-2)" "unprognostic (1.36e-1)" "potential prognostic unfavorable (3.81e-5)" "unprognostic (8.38e-3)" "unprognostic (6.95e-2)" "unprognostic (8.92e-2)" "unprognostic (1.85e-3)" "unprognostic (1.88e-2)" "unprognostic (6.59e-2)" "unprognostic (1.33e-2)" "unprognostic (7.58e-2)" "unprognostic (9.68e-2)" "unprognostic (1.71e-1)" "unprognostic (1.28e-1)" "unprognostic (2.44e-2)" "unprognostic (2.51e-2)" "unprognostic (5.36e-2)" "unprognostic (7.39e-2)" "unprognostic (8.96e-2)" "unprognostic (6.72e-2)" "unprognostic (5.55e-3)" "unprognostic (3.37e-1)" "unprognostic (1.49e-3)" "unprognostic (2.57e-1)" SLC35F1 "C6orf169, dJ230I3.1" ENSG00000196376 "Solute carrier family 35 member F1" Q5T1Q4 6 117907264-118317676 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.3;retina: 12.2" "Cell type enhanced" "Detected in many" "Astrocytes: 446.1;Bergmann glia: 759.8;Brain inhibitory neurons: 463.1;Oligodendrocyte progenitor cells: 2098.8;Retinal bipolar cells: 346.6;Schwann cells: 938.8" "Cell type enhanced" "Detected in all" "eccentric medium spiny neuron: 2028.3;oligodendrocyte precursor cell: 2361.1" "Group enriched" "Detected in some" 12 "Glioblastoma Multiforme (TCGA): 26.1;Skin Cutaneous Melanoma (TCGA): 6.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 6.0" "Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019576 Enhanced Approved "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 9 Nucleoplasm "Centriolar satellite, Cytosol" "HPA019576: " "unprognostic (3.43e-2)" "unprognostic (2.35e-1)" "unprognostic (7.18e-2)" "validated prognostic favorable (7.52e-5)" "validated prognostic favorable (1.42e-5)" "unprognostic (5.11e-2)" "unprognostic (9.26e-2)" "unprognostic (1.96e-2)" SLC35F2 FLJ13018 ENSG00000110660 "Solute carrier family 35 member F2" Q8IXU6 11 107790991-107928293 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 35.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 96.1;Cone photoreceptor cells: 72.5;Plasma cells: 85.8;Prostatic glandular cells: 78.9;Salivary acinar cells: 92.9;Suprabasal keratinocytes: 89.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Skeletal muscle - Endothelial cells, Skin - Keratinocyte (other), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048185, HPA060150" Enhanced Approved "Golgi apparatus" NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 26: Keratinocytes - Keratinization" 20 "Golgi apparatus" "HPA048185: , HPA060150: " "unprognostic (1.29e-1)" "unprognostic (2.50e-1)" "unprognostic (2.34e-1)" "potential prognostic unfavorable (6.77e-4)" "unprognostic (2.52e-2)" "unprognostic (8.32e-2)" "unprognostic (3.89e-2)" "unprognostic (5.25e-2)" "unprognostic (5.43e-3)" "potential prognostic unfavorable (2.82e-4)" "unprognostic (2.58e-2)" "unprognostic (4.38e-1)" "unprognostic (2.09e-2)" "unprognostic (9.12e-2)" "unprognostic (1.39e-1)" "unprognostic (3.85e-3)" "potential prognostic unfavorable (1.02e-4)" "potential prognostic unfavorable (2.89e-4)" "unprognostic (1.71e-2)" "unprognostic (1.72e-1)" "unprognostic (3.54e-1)" "potential prognostic unfavorable (6.72e-5)" "unprognostic (7.64e-2)" "unprognostic (2.44e-1)" "unprognostic (1.55e-2)" "unprognostic (1.99e-2)" "potential prognostic unfavorable (1.67e-4)" "unprognostic (1.09e-1)" "unprognostic (5.54e-2)" "unprognostic (1.08e-1)" "unprognostic (3.05e-1)" SLC35F3 FLJ37712 ENSG00000183780 "Solute carrier family 35 member F3" Q8IY50 1 233904676-234324511 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 15.5" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 297.8;Brain excitatory neurons: 450.7;Brain inhibitory neurons: 1145.0;Oligodendrocyte progenitor cells: 362.3;Other brain neurons: 345.3;Pancreatic islet cells: 552.9;pDCs: 237.5;Renal collecting duct intercalated cells: 225.4;Respiratory ionocytes: 287.0;Retinal amacrine cells: 183.1;Somatotrophs: 187.2" "Cell type enhanced" "Detected in all" "medium spiny neuron: 2781.8" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 5.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 35 "plasmacytoid DC: 3.5" "Lineage enriched" "Detected in single" 35 "dendritic cells: 3.5" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Kidney - Intercalated cells, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA051327, HPA061582" Uncertain Approved "Nucleoli,Golgi apparatus" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 27: Cerebellum - Synaptic function" "Cluster 53: Neurons - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 35: Neurons - Synaptic function & neurogenesis" "Golgi apparatus" Nucleoli "HPA051327: , HPA061582: " "unprognostic (3.68e-2)" "unprognostic (1.06e-1)" "unprognostic (9.67e-2)" "unprognostic (2.05e-1)" "unprognostic (5.12e-2)" "unprognostic (7.80e-3)" "unprognostic (4.85e-3)" "unprognostic (2.85e-2)" "unprognostic (3.71e-1)" "unprognostic (3.50e-2)" "unprognostic (5.98e-2)" "unprognostic (3.13e-1)" "unprognostic (3.52e-2)" "potential prognostic unfavorable (2.82e-4)" "unprognostic (2.67e-1)" "unprognostic (3.64e-1)" SLC35F4 "C14orf36, FLJ37712" ENSG00000151812 "Solute carrier family 35 member F4" A4IF30 14 57563920-57982194 "Essential proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 6 "brain: 13.2;retina: 6.0;seminal vesicle: 3.3" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 207.4;Brain inhibitory neurons: 212.0;Cone photoreceptor cells: 118.0;Oocytes: 138.2;Other brain neurons: 123.5;Pancreatic islet cells: 239.9;Peritubular myoid cells: 144.4;Retinal amacrine cells: 91.2;Retinal bipolar cells: 198.2;Retinal ganglion cells: 115.9;Rod photoreceptor cells: 474.6" "Cell type enhanced" "Detected in all" "eccentric medium spiny neuron: 642.1;mammillary body: 568.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 3.9" "Pancreas - Alpha cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA043853 Uncertain NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 25: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 109: Neurons - Neuronal signaling" "HPA043853: " SLC35F5 FLJ22004 ENSG00000115084 "Solute carrier family 35 member F5" Q8WV83 2 113705011-113756693 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Choroid plexus epithelial cells: 415.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034828, HPA049229" Uncertain Uncertain "Plasma membrane" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 100: Stratified epithelial cells - Barrier functions" "Plasma membrane" "HPA034828: , HPA049229: " "unprognostic (1.17e-2)" "potential prognostic unfavorable (3.24e-5)" "unprognostic (1.54e-1)" "unprognostic (2.07e-3)" "unprognostic (8.52e-2)" "unprognostic (2.40e-1)" "unprognostic (3.51e-2)" "unprognostic (3.98e-2)" "unprognostic (1.16e-2)" "unprognostic (9.24e-2)" "potential prognostic favorable (1.85e-5)" "unprognostic (1.51e-3)" "unprognostic (9.91e-2)" "unprognostic (1.11e-1)" "unprognostic (8.47e-2)" "unprognostic (4.11e-1)" "unprognostic (5.20e-2)" "unprognostic (1.82e-1)" "unprognostic (9.77e-2)" "unprognostic (1.95e-1)" "unprognostic (9.30e-3)" "unprognostic (1.40e-2)" "potential prognostic unfavorable (9.22e-4)" "unprognostic (1.42e-1)" "unprognostic (1.28e-1)" "unprognostic (1.84e-1)" "unprognostic (5.08e-2)" "unprognostic (8.92e-2)" "unprognostic (4.74e-1)" "unprognostic (6.25e-2)" "unprognostic (3.24e-2)" SLC35F6 "ANT2BP, C2orf18, FLJ20555, TANGO9" ENSG00000213699 "Solute carrier family 35 member F6" Q8N357 2 26764284-26781231 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cholangiocytes: 1.3;Foveolar cells: 1.0;Lymphatic endothelial cells: 1.1" "Cell type enhanced" "Detected in single" "Bergmann glia: 1.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Macrophages, Kidney - Macrophages, Lung - Macrophages, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034655 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 58: Skin - Keratinization" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 11 Vesicles "Nucleoplasm, Cytosol" "HPA034655: " "potential prognostic unfavorable (1.84e-4)" "unprognostic (2.87e-2)" "unprognostic (1.43e-2)" "unprognostic (2.47e-1)" "unprognostic (3.34e-2)" "unprognostic (1.11e-1)" "potential prognostic unfavorable (6.74e-4)" "unprognostic (1.55e-1)" "unprognostic (1.38e-1)" "potential prognostic favorable (4.56e-4)" "unprognostic (1.38e-1)" "unprognostic (1.43e-1)" "potential prognostic unfavorable (1.18e-4)" "unprognostic (7.47e-3)" "unprognostic (8.48e-3)" "unprognostic (6.81e-3)" "unprognostic (2.28e-1)" "unprognostic (2.77e-1)" "unprognostic (1.21e-1)" "unprognostic (3.65e-2)" "unprognostic (2.69e-1)" "unprognostic (1.21e-1)" "unprognostic (1.46e-1)" "unprognostic (1.56e-1)" "unprognostic (7.53e-3)" "unprognostic (1.04e-1)" "unprognostic (2.31e-1)" "unprognostic (3.94e-2)" "unprognostic (2.88e-2)" SLC35G1 "C10orf60, FLJ33990, TMEM20" ENSG00000176273 "Solute carrier family 35 member G1" Q2M3R5 10 93893973-93956062 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "intestine: 64.4" "Cell type enhanced" "Detected in many" "Colonocytes: 34.1;Enterocytes: 58.6;Late primary spermatocytes: 40.7;Leydig cells: 34.4;Parietal cells: 40.7;Peritubular myoid cells: 57.5;Pituicytes/FSCs: 62.5;Thyrotrophs: 43.9" "Cell type enhanced" "Detected in all" "fibroblast: 71.7" "Cancer enhanced" "Detected in many" "Lung Squamous Cell Carcinoma (TCGA): 7.7" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 44: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 4 "unprognostic (4.23e-1)" "unprognostic (7.92e-2)" "unprognostic (5.80e-2)" "unprognostic (4.47e-2)" "unprognostic (3.66e-2)" "unprognostic (6.60e-2)" "unprognostic (5.06e-3)" "unprognostic (4.17e-2)" "unprognostic (1.57e-1)" "unprognostic (6.07e-3)" "unprognostic (3.47e-3)" "unprognostic (1.85e-1)" "unprognostic (3.17e-3)" "unprognostic (1.08e-1)" "unprognostic (6.08e-2)" "unprognostic (2.68e-2)" "unprognostic (3.25e-1)" "unprognostic (1.80e-1)" "unprognostic (1.28e-1)" "unprognostic (1.24e-1)" "unprognostic (6.31e-2)" SLC35G2 "DKFZp564K2464, MGC3295, TMEM22" ENSG00000168917 "Solute carrier family 35 member G2" Q8TBE7 3 136818647-136855888 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 99.3;Astrocytes: 87.7;Early primary spermatocytes: 72.0;Gonadotrophs: 81.1;Lactotrophs: 98.1;Late primary spermatocytes: 89.5;Microglia: 70.6;Other brain neurons: 75.0;Pituicytes/FSCs: 71.5;Sertoli cells: 107.4;Somatotrophs: 74.2;Vascular endothelial cells: 69.5" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 24.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory CD8 T-cell: 1.0" "Lineage enriched" "Detected in single" 10 "T-cells: 1.0" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Breast - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052054, HPA064728" Approved Supported "Plasma membrane" NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 8 "Plasma membrane" "HPA052054: , HPA064728: " "unprognostic (1.25e-1)" "unprognostic (6.33e-3)" "unprognostic (1.31e-2)" "unprognostic (1.83e-3)" "unprognostic (1.63e-1)" "unprognostic (3.29e-2)" "potential prognostic unfavorable (6.98e-5)" "unprognostic (8.71e-2)" "unprognostic (1.45e-2)" "unprognostic (3.29e-1)" "unprognostic (1.06e-1)" "unprognostic (1.03e-1)" "potential prognostic unfavorable (3.17e-5)" "potential prognostic unfavorable (9.03e-6)" "unprognostic (3.30e-2)" "unprognostic (7.87e-2)" "unprognostic (2.87e-2)" "unprognostic (3.42e-2)" "unprognostic (3.59e-2)" "unprognostic (4.16e-2)" "potential prognostic unfavorable (3.60e-4)" "unprognostic (2.07e-1)" "unprognostic (1.31e-1)" "potential prognostic favorable (3.28e-4)" "unprognostic (2.53e-1)" "unprognostic (5.81e-3)" "unprognostic (2.39e-1)" "unprognostic (2.55e-2)" "unprognostic (4.38e-2)" SLC35G3 "AMAC1, FLJ40154, TMEM21A" ENSG00000164729 "Solute carrier family 35 member G3" Q8N808 17 35192520-35194393 "Predicted membrane proteins, Transporters" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 18 "testis: 2.4" "Group enriched" "Detected in some" 8 "Early spermatids: 19.9;Late primary spermatocytes: 23.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" SLC35G4 "AMAC1L1, SLC35G4P" ENSG00000236396 "Solute carrier family 35 member G4" P0C7Q5 18 11609596-11610612 "Predicted membrane proteins, Transporters" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" SLC35G5 "AMAC, AMAC1L2" ENSG00000177710 "Solute carrier family 35 member G5" Q96KT7 8 11331012-11332360 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 4 "testis: 2.2" "Not detected" "Not detected" "Low cell type specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 102: Non-specific - Mixed function" 1 SLC35G6 "AMAC1L3, TMEM21B" ENSG00000259224 "Solute carrier family 35 member G6" P0C7Q6 17 7481446-7483496 "Predicted membrane proteins, Transporters" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 12 "testis: 5.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" SLC36A1 "LYAAT-1, PAT1, TRAMD3" ENSG00000123643 "Solute carrier family 36 member 1" Q7Z2H8 5 151437046-151492379 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 97.0" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 74.5;Breast lactating cells: 112.5;Early spermatids: 167.3;Enterocytes: 90.2;Neutrophil progenitors: 70.9;Neutrophils: 109.4" "Cell type enhanced" "Detected in all" "upper rhombic lip: 150.8" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 199.7" "Group enriched" "Detected in many" 4 "basophil: 21.8;classical monocyte: 8.7;neutrophil: 19.7" "Group enriched" "Detected in many" 5 "granulocytes: 21.8;monocytes: 8.7" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035937 Approved NA NA "Cluster 41: Basophils - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 2: Neurons - Nucleosome" "Cluster 47: Leukemia - Hemostasis" "Cluster 24: Neutrophils - Innate immunity signal integration" 1 "HPA035937: " "unprognostic (8.78e-2)" "unprognostic (1.94e-1)" "unprognostic (7.68e-2)" "unprognostic (1.76e-1)" "unprognostic (1.96e-1)" "unprognostic (1.25e-1)" "unprognostic (2.01e-1)" "unprognostic (1.85e-1)" "unprognostic (1.76e-1)" "unprognostic (3.03e-3)" "unprognostic (2.59e-3)" "unprognostic (1.56e-1)" "unprognostic (9.26e-2)" "potential prognostic unfavorable (4.06e-6)" "unprognostic (1.07e-1)" "unprognostic (1.14e-2)" "unprognostic (3.09e-3)" "unprognostic (2.42e-2)" "unprognostic (1.66e-1)" "unprognostic (2.54e-3)" "unprognostic (2.18e-1)" "unprognostic (3.59e-2)" "unprognostic (1.37e-1)" "unprognostic (2.00e-1)" "unprognostic (2.27e-2)" "unprognostic (1.27e-2)" "unprognostic (1.85e-1)" "unprognostic (1.04e-1)" "unprognostic (6.82e-2)" "unprognostic (2.54e-1)" "unprognostic (1.96e-1)" SLC36A2 "PAT2, TRAMD1, tramdorin" ENSG00000186335 "Solute carrier family 36 member 2" Q495M3 5 151314972-151347590 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 59 "kidney: 63.0;skeletal muscle: 75.0;tongue: 27.9" "Group enriched" "Detected in some" 19 "Myonuclei: 737.6;Proximal tubule cells: 429.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney Renal Clear Cell Carcinoma (TCGA): 1.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Skeletal muscle - Skeletal myocytes, Testis - Late spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA044002, HPA062229" Enhanced NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 48: Non-specific - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" "HPA044002: , HPA062229: " "unprognostic (7.76e-3)" "unprognostic (1.91e-1)" "unprognostic (3.33e-2)" SLC36A3 "PAT3, TRAMD2, tramdorin2" ENSG00000186334 "Solute carrier family 36 member 3" Q495N2 5 151276358-151303766 "Metabolic proteins, Predicted membrane proteins, Transporters" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 30 "testis: 7.0" "Group enriched" "Detected in some" 11 "Early spermatids: 88.0;Late spermatids: 225.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" SLC36A4 "FLJ38932, PAT4" ENSG00000180773 "Solute carrier family 36 member 4" Q6YBV0 11 93144174-93197991 "Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Monocyte progenitors: 256.0;Neutrophil progenitors: 490.8;Neutrophils: 537.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017887 Enhanced Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 40: Non-specific - Mixed function" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 48: Neutrophils - Phagocytosis & degranulation" "Golgi apparatus, Plasma membrane, Cytosol" "HPA017887: " "unprognostic (3.33e-2)" "unprognostic (1.07e-2)" "unprognostic (9.95e-2)" "unprognostic (7.43e-2)" "unprognostic (4.70e-3)" "unprognostic (9.74e-2)" "unprognostic (3.15e-2)" "unprognostic (2.08e-2)" "unprognostic (1.86e-1)" "unprognostic (3.04e-3)" "potential prognostic favorable (2.86e-7)" "unprognostic (5.15e-2)" "unprognostic (1.68e-1)" "unprognostic (3.91e-3)" "unprognostic (5.38e-3)" "potential prognostic unfavorable (6.04e-5)" "unprognostic (4.74e-2)" "unprognostic (4.78e-3)" "unprognostic (2.13e-1)" "unprognostic (2.01e-2)" "unprognostic (2.03e-3)" "unprognostic (2.83e-2)" "unprognostic (6.46e-2)" "unprognostic (1.14e-2)" "unprognostic (1.77e-1)" "unprognostic (9.38e-2)" "unprognostic (3.03e-2)" "unprognostic (1.03e-2)" "unprognostic (7.36e-2)" "unprognostic (8.56e-3)" "unprognostic (2.75e-3)" SLC37A1 SPX1 ENSG00000160190 "Solute carrier family 37 member 1" P57057 21 42496008-42581440 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Sugar transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 43.1" "Cell type enhanced" "Detected in many" "Breast lactating cells: 682.2;Early spermatids: 210.5;Megakaryocyte progenitors: 221.7;Megakaryocytes: 210.2;Müller glia: 207.7;Somatotrophs: 246.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Spleen - B-cells (Spleen), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA030418, CAB034154" Approved NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 47: Leukemia - Hemostasis" "Cluster 4: Breast lactating luminal cells - Lactation" "CAB034154: , HPA030418: " "unprognostic (7.74e-2)" "potential prognostic unfavorable (2.37e-4)" "unprognostic (9.00e-2)" "unprognostic (5.51e-2)" "unprognostic (6.99e-3)" "unprognostic (3.19e-1)" "unprognostic (3.18e-2)" "unprognostic (2.27e-1)" "unprognostic (1.44e-1)" "unprognostic (2.85e-1)" "unprognostic (4.02e-2)" "unprognostic (2.77e-1)" "unprognostic (7.53e-2)" "unprognostic (3.45e-2)" "unprognostic (1.59e-2)" "unprognostic (1.18e-2)" "unprognostic (1.12e-2)" "unprognostic (9.04e-2)" "unprognostic (1.21e-1)" "unprognostic (3.55e-2)" "unprognostic (1.09e-1)" "unprognostic (1.59e-1)" "unprognostic (7.35e-3)" "unprognostic (8.46e-3)" "unprognostic (5.76e-2)" "unprognostic (7.77e-3)" "unprognostic (4.06e-1)" "unprognostic (1.15e-1)" "unprognostic (4.87e-2)" "unprognostic (1.88e-2)" "unprognostic (2.02e-1)" SLC37A2 "FLJ00171, SPX2" ENSG00000134955 "Solute carrier family 37 member 2" Q8TED4 11 125063302-125090516 "Predicted membrane proteins, Transporters" "Antiport, Sugar transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 48.9;salivary gland: 74.4;skin 1: 37.1" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 95.2;cDC: 27.6;Esophageal apical cells: 70.7;Hofbauer cells: 91.8;Kupffer cells: 70.7;Macrophages: 61.3;Microglia: 40.6;monocytes: 44.4;Salivary acinar cells: 48.4" "Cell type enriched" "Detected in some" 7 "central nervous system macrophage: 54.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "classical monocyte: 12.3;intermediate monocyte: 14.1;myeloid DC: 5.5;non-classical monocyte: 19.3" "Group enriched" "Detected in many" 9 "dendritic cells: 5.5;monocytes: 19.3" "Cancer enhanced" "Detected in many" "pancreatic cancer: 45.5" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Macrophages, Skeletal muscle - Macrophages, Skin - Keratinocyte (granular), Spleen - Macrophages, Stomach - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014948 Uncertain NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" "HPA014948: " "unprognostic (1.12e-1)" "unprognostic (4.11e-2)" "unprognostic (3.04e-1)" "unprognostic (1.39e-2)" "unprognostic (1.91e-1)" "unprognostic (2.64e-2)" "unprognostic (3.55e-2)" "unprognostic (1.42e-1)" "unprognostic (3.38e-1)" "unprognostic (2.05e-1)" "potential prognostic favorable (8.50e-4)" "unprognostic (1.62e-1)" "unprognostic (1.67e-2)" "unprognostic (1.93e-2)" "unprognostic (7.78e-2)" "unprognostic (1.16e-2)" "unprognostic (3.78e-3)" "unprognostic (3.92e-2)" "unprognostic (1.85e-1)" "unprognostic (1.03e-1)" "unprognostic (4.82e-2)" "unprognostic (1.45e-2)" "unprognostic (1.08e-2)" "unprognostic (4.10e-1)" "unprognostic (2.17e-2)" "unprognostic (1.38e-1)" "unprognostic (6.54e-2)" "unprognostic (2.11e-3)" "unprognostic (7.75e-3)" "unprognostic (2.03e-1)" "unprognostic (7.50e-2)" SLC37A3 "DKFZp761N0624, SPX3" ENSG00000157800 "Solute carrier family 37 member 3" Q8NCC5 7 140293693-140404433 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 158.8;Neutrophils: 300.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 34: Non-specific - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 5 "unprognostic (1.54e-2)" "unprognostic (1.67e-1)" "unprognostic (4.82e-2)" "unprognostic (2.59e-3)" "unprognostic (1.55e-1)" "unprognostic (1.17e-1)" "unprognostic (3.91e-2)" "unprognostic (1.72e-2)" "unprognostic (2.49e-1)" "unprognostic (1.31e-2)" "unprognostic (1.46e-1)" "unprognostic (4.22e-2)" "unprognostic (1.02e-2)" "potential prognostic unfavorable (1.03e-5)" "unprognostic (5.58e-3)" "unprognostic (2.98e-2)" "unprognostic (2.62e-2)" "unprognostic (1.62e-1)" "unprognostic (1.45e-1)" "unprognostic (1.62e-1)" "unprognostic (3.66e-1)" "unprognostic (5.99e-2)" "unprognostic (1.19e-2)" "unprognostic (2.26e-1)" "unprognostic (4.93e-1)" "unprognostic (3.13e-1)" "unprognostic (1.57e-1)" "unprognostic (2.26e-1)" "unprognostic (2.48e-1)" "unprognostic (2.14e-2)" "unprognostic (7.95e-2)" SLC37A4 "G6PT, G6PT1, G6PT2, G6PT3, GSD1b, GSD1c, GSD1d, SPX4" ENSG00000137700 "Solute carrier family 37 member 4" 11 119023751-119030906 "Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 47.5;liver: 134.4" "Cell type enhanced" "Detected in some" "Astrocytes: 7.1;Bergmann glia: 5.1;Brain excitatory neurons: 4.5;Brain inhibitory neurons: 4.2;Distal convoluted tubule cells: 4.8;Ependymal cells: 4.1;Loop of henle epithelial cells: 7.5;Microglia: 12.8;Oligodendrocyte progenitor cells: 4.5;Other brain neurons: 4.3;Papillary tip epithelial cells: 4.4;Podocytes: 15.2;Proximal tubule cells: 30.1;Renal collecting duct intercalated cells: 6.6;Renal collecting duct principal cells: 6.5;Renal connecting tubule cells: 4.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038939, HPA038940" Enhanced Approved Mitochondria NA NA "Cluster 24: Non-specific - Transcription" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 21: Non-specific - Metabolism" "Cluster 24: Non-specific - Unknown function" "Cluster 88: Proximal tubular cells - Transmembrane transport" 3 Mitochondria "HPA038939: , HPA038940: " "potential prognostic unfavorable (1.05e-4)" "unprognostic (1.09e-1)" "unprognostic (1.22e-1)" "unprognostic (2.08e-3)" "unprognostic (2.73e-1)" "unprognostic (2.23e-1)" "unprognostic (2.36e-1)" "potential prognostic unfavorable (2.15e-4)" "unprognostic (3.33e-1)" "unprognostic (2.39e-3)" "unprognostic (1.02e-1)" "potential prognostic favorable (1.16e-4)" "unprognostic (2.69e-1)" "potential prognostic favorable (3.30e-5)" "unprognostic (2.70e-2)" "unprognostic (1.35e-1)" "unprognostic (1.58e-1)" "unprognostic (2.86e-2)" "unprognostic (1.44e-3)" "unprognostic (7.05e-2)" "unprognostic (1.65e-2)" "unprognostic (1.55e-1)" "unprognostic (6.19e-2)" "unprognostic (3.77e-1)" "unprognostic (8.10e-3)" "unprognostic (4.56e-3)" "unprognostic (1.16e-1)" "unprognostic (6.54e-2)" "unprognostic (6.82e-2)" SLC38A1 "ATA1, NAT2, SAT1" ENSG00000111371 "Solute carrier family 38 member 1" Q9H2H9 12 46183063-46270017 "FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Ion transport, Sodium transport, Symport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bergmann glia: 861.4;NK-cells: 605.1;Renal collecting duct principal cells: 550.6;Retinal bipolar cells: 573.0;T-cells: 547.3" "Cell type enhanced" "Detected in all" "Bergmann glia: 889.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Breast - Breast glandular cells, Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Smooth muscle cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039460, HPA052272" Uncertain Supported NA NA "Cluster 24: Non-specific - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 41 "HPA039460: , HPA052272: " "unprognostic (1.14e-1)" "unprognostic (1.42e-2)" "unprognostic (2.18e-1)" "unprognostic (7.39e-2)" "unprognostic (9.73e-2)" "unprognostic (4.74e-3)" "unprognostic (1.46e-1)" "unprognostic (1.18e-1)" "unprognostic (3.20e-1)" "unprognostic (1.36e-3)" "potential prognostic favorable (9.92e-5)" "unprognostic (7.24e-2)" "unprognostic (3.07e-1)" "potential prognostic unfavorable (2.07e-7)" "unprognostic (2.87e-3)" "unprognostic (1.39e-3)" "unprognostic (2.25e-2)" "unprognostic (7.03e-2)" "unprognostic (1.09e-2)" "unprognostic (1.64e-2)" "unprognostic (4.23e-3)" "unprognostic (1.81e-2)" "unprognostic (4.39e-3)" "unprognostic (1.17e-2)" "unprognostic (3.25e-2)" "unprognostic (1.47e-2)" "unprognostic (1.02e-1)" "unprognostic (3.69e-2)" "unprognostic (1.53e-1)" "unprognostic (7.74e-2)" "unprognostic (1.20e-2)" SLC38A10 "MGC15523, PP1744" ENSG00000157637 "Solute carrier family 38 member 10" Q9HBR0 17 81244811-81295547 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021374, HPA023161, HPA024631" Enhanced Enhanced "Golgi apparatus" NA NA 34000000 "Cluster 25: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 18: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 22 "Golgi apparatus" "HPA021374: , HPA023161: , HPA024631: " "unprognostic (6.39e-2)" "unprognostic (2.77e-1)" "unprognostic (9.97e-3)" "unprognostic (1.52e-2)" "unprognostic (1.73e-1)" "unprognostic (2.02e-1)" "unprognostic (7.97e-2)" "unprognostic (1.18e-1)" "unprognostic (2.41e-1)" "unprognostic (2.96e-2)" "unprognostic (5.79e-2)" "unprognostic (2.39e-1)" "unprognostic (4.14e-2)" "unprognostic (3.12e-1)" "unprognostic (5.68e-2)" "unprognostic (2.85e-1)" "unprognostic (1.00e-1)" "unprognostic (2.41e-2)" "unprognostic (1.08e-1)" "unprognostic (1.76e-1)" "unprognostic (4.46e-2)" "potential prognostic favorable (1.75e-4)" "unprognostic (2.13e-1)" "unprognostic (2.36e-1)" "unprognostic (1.34e-1)" "unprognostic (8.65e-3)" "unprognostic (1.52e-1)" "unprognostic (2.00e-1)" "unprognostic (2.04e-1)" "unprognostic (1.59e-1)" "unprognostic (2.61e-1)" SLC38A11 "AVT2, FLJ39822" ENSG00000169507 "Solute carrier family 38 member 11" Q08AI6 2 164894354-164955525 "Predicted membrane proteins, Transporters" "Amino-acid transport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 24.4;epididymis: 30.4" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 244.6;Choroid plexus epithelial cells: 302.0;Epididymal basal cells: 149.9;Epididymal clear cells: 106.1;Loop of henle epithelial cells: 145.9;Mast cells: 223.9;Neuroendocrine cells: 657.4;Pericytes: 177.3;Prostatic glandular cells: 161.4;Renal collecting duct intercalated cells: 148.0;Renal collecting duct principal cells: 152.5;Renal connecting tubule cells: 201.5;Retinal pigment epithelial cells: 132.2;Vascular smooth muscle cells: 261.4" "Group enriched" "Detected in many" 16 "choroid plexus epithelial cell: 1236.5;pericyte: 1722.3;vascular associated smooth muscle cell: 1915.6" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 18.3" "Group enriched" "Detected in all" 5 "cerebral cortex: 16.5;choroid plexus: 50.8" "Group enriched" "Detected in some" 27 "memory B-cell: 1.6;naive B-cell: 3.8" "Lineage enriched" "Detected in single" 38 "B-cells: 3.8" "Cancer enriched" "Detected in some" 6 "Rhabdoid: 10.1" "Adrenal gland - Adrenal medulla cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA043432 Uncertain NA NA "Cluster 34: B-cells - Unknown function" "Cluster 22: Epididymis - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" "HPA043432: " "unprognostic (2.66e-2)" "unprognostic (3.34e-2)" "unprognostic (2.08e-1)" "unprognostic (3.79e-1)" "unprognostic (1.45e-1)" "unprognostic (7.13e-2)" "validated prognostic favorable (2.15e-6)" "validated prognostic favorable (4.51e-4)" "unprognostic (7.33e-3)" "unprognostic (1.87e-3)" "unprognostic (8.39e-2)" "unprognostic (5.97e-2)" "unprognostic (1.19e-1)" "unprognostic (3.92e-2)" "unprognostic (2.77e-3)" "unprognostic (2.70e-1)" "unprognostic (8.93e-2)" "unprognostic (3.33e-2)" "unprognostic (1.99e-1)" "unprognostic (1.70e-1)" "unprognostic (3.96e-1)" "unprognostic (1.46e-1)" SLC38A2 "ATA2, KIAA1382, SAT2, SNAT2" ENSG00000134294 "Solute carrier family 38 member 2" Q96QD8 12 46358188-46372773 "Essential proteins, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Ion transport, Sodium transport, Symport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 1107.2;Suprabasal keratinocytes: 912.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035180, HPA069672" Approved Supported "Plasma membrane" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 76: Non-specific - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 26: Keratinocytes - Keratinization" 10 "Plasma membrane" "HPA035180: , HPA069672: " "unprognostic (3.25e-1)" "unprognostic (2.34e-3)" "unprognostic (1.36e-2)" "unprognostic (2.68e-3)" "unprognostic (2.81e-1)" "unprognostic (2.52e-1)" "unprognostic (1.78e-1)" "unprognostic (4.27e-1)" "unprognostic (8.47e-2)" "unprognostic (2.64e-2)" "unprognostic (1.90e-3)" "unprognostic (1.92e-1)" "unprognostic (2.69e-1)" "unprognostic (9.02e-2)" "unprognostic (8.21e-2)" "potential prognostic unfavorable (1.52e-4)" "unprognostic (2.58e-2)" "unprognostic (2.74e-1)" "unprognostic (7.78e-2)" "unprognostic (2.48e-1)" "unprognostic (1.68e-1)" "unprognostic (2.10e-2)" "potential prognostic unfavorable (2.02e-4)" "unprognostic (7.07e-2)" "unprognostic (1.25e-1)" "unprognostic (2.27e-1)" "unprognostic (4.40e-2)" "unprognostic (1.83e-1)" "unprognostic (1.06e-1)" "unprognostic (1.21e-1)" "unprognostic (1.19e-2)" SLC38A3 "G17, SN1" ENSG00000188338 "Solute carrier family 38 member 3" Q99624 3 50205246-50221486 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Antiport, Ion transport, Sodium transport, Symport, Transport" "Disease variant, Epilepsy, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "liver: 310.0;retina: 160.5" "Cell type enhanced" "Detected in some" "Astrocytes: 23.1;Breast lactating cells: 23.1;Cholangiocytes: 21.6;Cone photoreceptor cells: 120.1;Ependymal cells: 30.1;Hepatocytes: 134.6;Müller glia: 79.0;Myonuclei: 34.0;Retinal bipolar cells: 68.0;Retinal pigment epithelial cells: 42.6;Rod photoreceptor cells: 77.4" "Cell type enhanced" "Detected in many" "endothelial cell: 71.9;ependymal cell: 40.9" "Cancer enriched" "Detected in many" 7 "Liver Hepatocellular Carcinoma (TCGA): 234.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.8" "Lineage enriched" "Detected in single" 7 "granulocytes: 2.8" "Cancer enhanced" "Detected in many" "liver cancer: 7.0" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Skin - Hair cortex cells, Skin - Inner root sheath cells, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031871 Approved Microtubules,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 19: Astrocytes - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" Cytosol Microtubules "HPA031871: " "unprognostic (4.38e-1)" "unprognostic (9.49e-2)" "unprognostic (1.56e-1)" "unprognostic (8.55e-2)" "unprognostic (3.91e-2)" "unprognostic (4.34e-2)" "unprognostic (1.05e-2)" "potential prognostic unfavorable (1.59e-9)" "unprognostic (4.32e-1)" "unprognostic (3.06e-2)" "unprognostic (3.60e-3)" "potential prognostic favorable (8.05e-4)" "unprognostic (2.81e-1)" "unprognostic (1.36e-1)" "potential prognostic unfavorable (5.35e-4)" "unprognostic (9.85e-2)" "unprognostic (7.94e-2)" "unprognostic (3.85e-2)" "unprognostic (1.65e-1)" "unprognostic (2.46e-1)" "unprognostic (1.09e-1)" SLC38A4 "ATA3, NAT3, PAAT" ENSG00000139209 "Solute carrier family 38 member 4" Q969I6 12 46764761-46832408 "FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Ion transport, Sodium transport, Symport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 61 "liver: 570.3" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 536.3" "Cell type enhanced" "Detected in many" "fibroblast: 23.6" "Cancer enriched" "Detected in many" 12 "Liver Hepatocellular Carcinoma (TCGA): 81.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 8.8" "Liver - Hepatocytes, Liver - Hepatocytes, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 1 "unprognostic (2.79e-1)" "unprognostic (1.18e-2)" "unprognostic (1.60e-2)" "unprognostic (3.54e-2)" "unprognostic (4.70e-3)" "unprognostic (3.89e-1)" "unprognostic (6.51e-2)" "unprognostic (7.59e-2)" "unprognostic (8.78e-2)" "unprognostic (1.81e-2)" "unprognostic (4.68e-2)" "unprognostic (1.34e-3)" "unprognostic (1.66e-3)" "unprognostic (1.91e-1)" "unprognostic (3.82e-1)" "unprognostic (1.47e-3)" "unprognostic (5.04e-1)" "unprognostic (8.41e-2)" "unprognostic (1.03e-2)" "unprognostic (9.43e-2)" "unprognostic (2.32e-1)" "unprognostic (2.15e-2)" SLC38A5 "JM24, SN2" ENSG00000017483 "Solute carrier family 38 member 5" Q8WUX1 X 48458537-48470260 "Metabolic proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "pancreas: 223.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 33.7;Enteric stem cells: 27.3;Epididymal basal cells: 32.2;Erythrocyte progenitors: 95.7;Erythrocytes: 38.7;Esophageal basal cells: 32.7;Gastric chief cells: 44.8;Pancreatic acinar cells: 121.0;Plasma cells: 71.3" "Cell type enriched" "Detected in some" 18 "endothelial cell: 334.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Myeloma: 246.7" "Prostate - Fibroblasts, Stomach - Chief cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047411 Enhanced Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 8: Pancreas - Proteolysis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 104: Brain endothelial cells - Blood brain barrier" 9 "Vesicles, Plasma membrane" Cytosol "HPA047411: " "unprognostic (1.27e-1)" "unprognostic (8.01e-2)" "unprognostic (2.25e-1)" "unprognostic (9.54e-3)" "unprognostic (3.64e-2)" "unprognostic (3.50e-3)" "potential prognostic favorable (4.92e-4)" "unprognostic (1.05e-1)" "unprognostic (2.21e-1)" "validated prognostic unfavorable (1.46e-8)" "validated prognostic unfavorable (3.10e-6)" "unprognostic (2.61e-2)" "unprognostic (9.06e-3)" "unprognostic (1.19e-1)" "unprognostic (8.11e-3)" "unprognostic (9.16e-2)" "unprognostic (1.53e-1)" "unprognostic (3.33e-1)" "potential prognostic unfavorable (3.36e-4)" "unprognostic (4.57e-2)" "potential prognostic unfavorable (7.10e-4)" "unprognostic (6.43e-2)" "unprognostic (2.17e-2)" "unprognostic (3.39e-3)" "unprognostic (1.20e-1)" "unprognostic (3.28e-1)" "unprognostic (3.14e-3)" "unprognostic (2.21e-1)" "unprognostic (1.65e-1)" "unprognostic (1.70e-2)" SLC38A6 NAT-1 ENSG00000139974 "Solute carrier family 38 member 6" Q8IZM9 14 60981114-61114316 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 199.9;Hofbauer cells: 185.9;Late primary spermatocytes: 158.6;Late spermatids: 221.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018508 Approved Approved "Plasma membrane,Cell Junctions,Microtubules" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 1 "Cell Junctions" "Plasma membrane, Microtubules" "HPA018508: " "unprognostic (3.87e-1)" "unprognostic (4.41e-2)" "unprognostic (3.59e-1)" "unprognostic (1.02e-1)" "unprognostic (1.35e-1)" "unprognostic (1.48e-1)" "unprognostic (1.53e-2)" "unprognostic (8.56e-2)" "unprognostic (4.14e-3)" "unprognostic (4.72e-2)" "unprognostic (1.83e-2)" "unprognostic (2.94e-2)" "unprognostic (1.63e-2)" "potential prognostic unfavorable (1.00e-7)" "unprognostic (1.07e-1)" "unprognostic (6.75e-2)" "unprognostic (6.81e-2)" "unprognostic (4.80e-2)" "unprognostic (6.12e-2)" "unprognostic (4.21e-2)" "unprognostic (5.30e-2)" "unprognostic (4.81e-2)" "unprognostic (4.92e-3)" "unprognostic (8.70e-2)" "unprognostic (5.08e-2)" "unprognostic (1.46e-1)" "unprognostic (4.52e-2)" "unprognostic (2.48e-2)" "unprognostic (2.97e-2)" "unprognostic (1.60e-1)" "unprognostic (1.74e-1)" SLC38A7 FLJ10815 ENSG00000103042 "Solute carrier family 38 member 7" Q9NVC3 16 58665109-58684770 "Predicted membrane proteins, Transporters" "Amino-acid transport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 32.7" "Group enriched" "Detected in many" 11 "Early spermatids: 393.1;Late spermatids: 1386.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Heart muscle - Cardiomyocytes, Lung - Macrophages, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041777, HPA049428" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 79: Testis - Spermatogenesis" "Cluster 38: Sub-cortical - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 44 "Plasma membrane, Cytosol" Nucleoplasm "HPA041777: , HPA049428: " "unprognostic (3.89e-2)" "potential prognostic unfavorable (2.80e-5)" "unprognostic (4.74e-2)" "unprognostic (1.26e-2)" "unprognostic (4.33e-2)" "unprognostic (5.37e-2)" "unprognostic (2.63e-1)" "unprognostic (1.76e-1)" "unprognostic (2.91e-3)" "unprognostic (2.61e-1)" "unprognostic (1.12e-1)" "unprognostic (5.61e-2)" "unprognostic (2.27e-1)" "unprognostic (6.38e-3)" "unprognostic (1.24e-2)" "unprognostic (3.30e-2)" "unprognostic (2.47e-2)" "unprognostic (8.19e-3)" "unprognostic (5.11e-2)" "unprognostic (1.01e-1)" "unprognostic (7.48e-2)" "unprognostic (1.35e-1)" "unprognostic (2.57e-3)" "unprognostic (1.03e-1)" "unprognostic (2.50e-2)" "unprognostic (4.18e-2)" "unprognostic (8.92e-3)" "unprognostic (1.29e-1)" "unprognostic (1.22e-1)" "unprognostic (3.29e-2)" "unprognostic (1.17e-1)" SLC38A8 ENSG00000166558 "Solute carrier family 38 member 8" A6NNN8 16 84009667-84042795 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 2.3" "Cell type enriched" "Detected in some" 5 "Oocytes: 188.8" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in some" 8 "Kidney Chromophobe (TCGA): 3.8;Skin Cutaneous Melanoma (TCGA): 9.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "skin cancer: 1.0" "Testis - Late spermatids" "Low region specificity" "Detected in single" "Not detected" "Not detected" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 41: Oocytes - Oogenesis" "unprognostic (2.82e-1)" "unprognostic (4.00e-2)" SLC38A9 FLJ90709 ENSG00000177058 "Solute carrier family 38 member 9" Q8NBW4 5 55625845-55773194 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 54.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 382.3;Early spermatids: 337.4;Migrating cytotrophoblasts: 411.1;Syncytiotrophoblasts: 1294.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043785, HPA061702" Uncertain Supported Vesicles NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 27 Vesicles "HPA043785: , HPA061702: " "unprognostic (1.04e-1)" "unprognostic (1.10e-1)" "unprognostic (1.06e-2)" "unprognostic (2.25e-1)" "unprognostic (7.14e-2)" "unprognostic (9.19e-2)" "unprognostic (9.23e-2)" "unprognostic (4.46e-2)" "unprognostic (8.35e-2)" "unprognostic (2.91e-3)" "unprognostic (6.98e-3)" "unprognostic (5.22e-2)" "unprognostic (1.56e-1)" "unprognostic (1.24e-2)" "unprognostic (3.70e-2)" "unprognostic (5.82e-2)" "unprognostic (1.21e-1)" "unprognostic (1.46e-1)" "unprognostic (2.27e-1)" "unprognostic (9.83e-2)" "unprognostic (7.86e-2)" "unprognostic (6.64e-2)" "unprognostic (4.02e-3)" "unprognostic (3.02e-1)" "unprognostic (2.37e-1)" "unprognostic (5.71e-2)" "unprognostic (1.77e-1)" "unprognostic (1.68e-1)" "unprognostic (1.56e-1)" "unprognostic (4.60e-1)" "unprognostic (1.26e-1)" SLC39A1 "ZIP1, ZIRTL" ENSG00000143570 "Solute carrier family 39 member 1" Q9NY26 1 153959099-153968184 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 64.6;Epididymal basal cells: 38.4;Extravillous trophoblasts: 57.2;Migrating cytotrophoblasts: 59.7;Paneth cells: 34.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 44: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 9 "unprognostic (1.56e-1)" "unprognostic (9.05e-2)" "unprognostic (3.45e-1)" "potential prognostic unfavorable (5.99e-4)" "unprognostic (1.43e-1)" "unprognostic (2.93e-2)" "unprognostic (4.08e-2)" "unprognostic (6.64e-2)" "potential prognostic unfavorable (9.96e-4)" "unprognostic (2.17e-1)" "unprognostic (6.02e-3)" "unprognostic (3.53e-2)" "unprognostic (3.22e-2)" "potential prognostic unfavorable (7.26e-9)" "unprognostic (2.01e-3)" "potential prognostic unfavorable (3.76e-4)" "unprognostic (2.02e-2)" "unprognostic (9.56e-2)" "unprognostic (4.12e-2)" "unprognostic (3.53e-1)" "unprognostic (3.31e-1)" "unprognostic (3.09e-3)" "unprognostic (2.82e-1)" "unprognostic (1.12e-1)" "unprognostic (7.36e-3)" "unprognostic (3.51e-1)" "unprognostic (7.78e-3)" "unprognostic (5.16e-2)" "unprognostic (1.42e-1)" "unprognostic (8.79e-2)" "unprognostic (1.48e-1)" SLC39A10 "DKFZp564L2123, FLJ90515, KIAA1265" ENSG00000196950 "Solute carrier family 39 member 10" Q9ULF5 2 195575977-195737702 "Essential proteins, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 44.1;thyroid gland: 45.2" "Cell type enhanced" "Detected in many" "Microglia: 205.7;Prostatic glandular cells: 188.0" "Cell type enriched" "Detected in all" 10 "endothelial cell: 2874.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Inner root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036512, HPA036513, HPA066087" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 330000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 104: Brain endothelial cells - Blood brain barrier" 42 "Nucleoplasm, Cytosol" "Plasma membrane" "HPA036512: , HPA036513: , HPA066087: " "unprognostic (5.77e-2)" "unprognostic (2.43e-1)" "unprognostic (5.96e-2)" "unprognostic (6.02e-3)" "unprognostic (2.08e-1)" "unprognostic (1.73e-2)" "unprognostic (2.82e-2)" "unprognostic (9.20e-2)" "unprognostic (1.64e-1)" "unprognostic (2.22e-1)" "potential prognostic favorable (2.71e-5)" "unprognostic (5.32e-2)" "unprognostic (1.11e-1)" "potential prognostic unfavorable (3.20e-4)" "unprognostic (8.13e-3)" "unprognostic (5.40e-3)" "potential prognostic unfavorable (9.55e-5)" "unprognostic (6.25e-2)" "unprognostic (3.50e-2)" "unprognostic (3.39e-2)" "unprognostic (2.72e-2)" "validated prognostic unfavorable (1.08e-5)" "validated prognostic unfavorable (6.58e-4)" "unprognostic (1.03e-1)" "unprognostic (1.59e-1)" "unprognostic (6.16e-2)" "unprognostic (7.42e-3)" "unprognostic (1.69e-1)" "unprognostic (1.89e-1)" "unprognostic (7.88e-2)" "unprognostic (1.42e-1)" SLC39A11 C17orf26 ENSG00000133195 "Solute carrier family 39 member 11" Q8N1S5 17 72645949-73092712 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 570.7;Bergmann glia: 474.9;Neutrophil progenitors: 637.1;Oligodendrocytes: 455.8" "Cell type enhanced" "Detected in all" "astrocyte: 767.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Macrophages, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021455 Approved Nucleoplasm NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 60: Stomach - Digestion" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 7 Nucleoplasm "HPA021455: " "unprognostic (1.60e-1)" "unprognostic (8.83e-3)" "unprognostic (2.94e-1)" "unprognostic (1.10e-2)" "unprognostic (1.54e-3)" "unprognostic (6.42e-2)" "unprognostic (6.18e-2)" "unprognostic (3.42e-3)" "unprognostic (3.74e-2)" "unprognostic (2.26e-2)" "unprognostic (1.85e-2)" "potential prognostic unfavorable (6.50e-4)" "unprognostic (1.00e-2)" "unprognostic (6.47e-2)" "unprognostic (4.05e-2)" "unprognostic (2.99e-3)" "unprognostic (2.29e-2)" "unprognostic (4.12e-1)" "unprognostic (7.09e-3)" "unprognostic (4.21e-2)" "unprognostic (6.37e-3)" "unprognostic (1.38e-2)" "unprognostic (4.92e-1)" "unprognostic (3.45e-1)" "unprognostic (8.84e-2)" "unprognostic (2.02e-2)" "unprognostic (6.44e-2)" "unprognostic (4.09e-2)" "unprognostic (2.27e-1)" "potential prognostic unfavorable (3.24e-4)" "unprognostic (1.32e-1)" SLC39A12 FLJ30499 ENSG00000148482 "Solute carrier family 39 member 12" Q504Y0 10 17951839-18043292 "Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "choroid plexus: 647.0" "Group enriched" "Detected in some" 7 "Choroid plexus epithelial cells: 1282.7;Retinal pigment epithelial cells: 912.3" "Cell type enriched" "Detected in many" 6 "choroid plexus epithelial cell: 1084.0" "Cancer enriched" "Detected in single" 7 "Glioblastoma Multiforme (TCGA): 4.8" "Region enriched" "Detected in all" 16 "choroid plexus: 717.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 26 "unprognostic (3.03e-1)" "unprognostic (2.50e-2)" SLC39A13 FLJ25785 ENSG00000165915 "Solute carrier family 39 member 13" Q96H72 11 47407132-47416496 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Late spermatids: 1677.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 160.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Liver - Vascular endothelial cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043971 Approved NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 18: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 4 "HPA043971: " "unprognostic (3.28e-1)" "unprognostic (2.53e-1)" "unprognostic (2.62e-1)" "unprognostic (2.24e-3)" "potential prognostic unfavorable (4.92e-4)" "unprognostic (4.65e-1)" "unprognostic (3.18e-3)" "unprognostic (1.94e-1)" "unprognostic (4.47e-2)" "unprognostic (2.75e-1)" "unprognostic (2.36e-2)" "unprognostic (8.02e-3)" "potential prognostic favorable (1.40e-5)" "potential prognostic unfavorable (6.61e-4)" "unprognostic (2.54e-1)" "unprognostic (1.52e-1)" "unprognostic (2.28e-2)" "unprognostic (3.88e-3)" "unprognostic (8.84e-2)" "unprognostic (2.21e-3)" "unprognostic (1.22e-1)" "unprognostic (2.23e-2)" "unprognostic (5.72e-2)" "unprognostic (1.98e-2)" "unprognostic (1.70e-1)" "potential prognostic favorable (3.49e-4)" "unprognostic (2.44e-1)" "unprognostic (4.86e-2)" "unprognostic (1.71e-1)" "unprognostic (1.02e-1)" "unprognostic (1.36e-1)" SLC39A14 "KIAA0062, NET34, ZIP14" ENSG00000104635 "Solute carrier family 39 member 14" Q15043 8 22367278-22434129 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Disease variant, Dystonia, Neurodegeneration, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 515.9;pancreas: 235.9" "Cell type enhanced" "Detected in many" "Endometrial luminal cells: 588.4;Hepatocytes: 677.6;Pancreatic acinar cells: 748.1;Pancreatic duct cells: 242.2;Salivary myoepithelial cells: 220.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016508, HPA056732" Enhanced Approved "Endoplasmic reticulum,Golgi apparatus,Plasma membrane" NA NA 1000000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 70: Non-specific - Protein processing" "Cluster 12: Non-specific - Vasculature" "Cluster 18: Liver cancer - Metabolism" "Cluster 103: Non-specific - Basic cellular processes" 19 "Endoplasmic reticulum, Golgi apparatus, Plasma membrane" "HPA016508: , HPA056732: " "unprognostic (2.59e-1)" "unprognostic (3.22e-1)" "unprognostic (6.10e-2)" "unprognostic (1.48e-2)" "unprognostic (8.06e-3)" "unprognostic (2.52e-1)" "unprognostic (5.15e-3)" "potential prognostic unfavorable (5.11e-4)" "unprognostic (3.80e-2)" "unprognostic (3.24e-2)" "unprognostic (1.90e-2)" "unprognostic (1.06e-1)" "potential prognostic unfavorable (3.28e-4)" "unprognostic (4.12e-1)" "unprognostic (1.35e-2)" "unprognostic (1.67e-2)" "unprognostic (6.70e-2)" "unprognostic (1.22e-1)" "unprognostic (2.01e-1)" "unprognostic (3.67e-3)" "unprognostic (4.64e-2)" "unprognostic (3.59e-2)" "unprognostic (1.45e-1)" "unprognostic (4.03e-1)" "unprognostic (1.33e-2)" "unprognostic (4.15e-2)" "unprognostic (1.29e-1)" "unprognostic (8.68e-2)" "unprognostic (9.64e-2)" "unprognostic (2.85e-2)" "unprognostic (9.35e-2)" SLC39A2 ZIP2 ENSG00000165794 "Solute carrier family 39 member 2" Q9NP94 14 20999255-21001871 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 18.0;seminal vesicle: 31.3;skin 1: 35.8" "Cell type enhanced" "Detected in some" "Enteric stem cells: 6.4;Esophageal apical cells: 33.8;Esophageal basal cells: 14.9;Esophageal suprabasal cells: 59.2;Müller glia: 18.2;Ocular epithelial cells: 13.3;Submucosal glandular cells: 5.8;Suprabasal keratinocytes: 17.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 19.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Esophageal cancer: 2.2;head and neck cancer: 2.5" "Skin - Keratinocyte (other)" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA030489, HPA073231" Uncertain Approved "Plasma membrane,Cytoplasmic bodies" NA NA "Cluster 58: Skin - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 45 "Plasma membrane" "Cytoplasmic bodies" "HPA030489: , HPA073231: " "unprognostic (1.89e-2)" "unprognostic (1.39e-1)" "unprognostic (2.24e-1)" "unprognostic (5.17e-3)" "unprognostic (1.14e-1)" "unprognostic (3.12e-2)" "unprognostic (1.94e-1)" "unprognostic (4.08e-1)" "unprognostic (5.19e-2)" "unprognostic (2.76e-1)" "unprognostic (3.80e-1)" "unprognostic (3.32e-1)" "unprognostic (1.78e-1)" "unprognostic (1.85e-1)" "unprognostic (5.92e-2)" "unprognostic (2.35e-2)" SLC39A3 ZIP3 ENSG00000141873 "Solute carrier family 39 member 3" Q9BRY0 19 2732204-2740028 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 97.1" "Cell type enhanced" "Detected in some" "Early spermatids: 3.2;Hematopoietic stem cells: 2.9;Hepatic stellate cells: 6.5;Late primary spermatocytes: 5.2;Late spermatids: 11.3;Medullary thymic epithelial cells: 2.4;Megakaryocyte progenitors: 2.6;Megakaryocyte-Erythroid progenitors: 4.3;Retinal pigment epithelial cells: 4.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "HPA042139, HPA058526" Uncertain Approved Vesicles NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 67: Testis - Mixed function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 11 Vesicles "HPA042139: , HPA058526: " "unprognostic (1.59e-1)" "unprognostic (9.77e-2)" "unprognostic (6.46e-2)" "unprognostic (1.19e-2)" "unprognostic (6.27e-2)" "unprognostic (4.84e-2)" "unprognostic (3.30e-1)" "unprognostic (1.69e-1)" "unprognostic (1.27e-1)" "unprognostic (1.31e-1)" "unprognostic (2.93e-3)" "unprognostic (2.26e-3)" "unprognostic (6.02e-2)" "unprognostic (3.58e-3)" "unprognostic (1.52e-1)" "unprognostic (1.80e-2)" "unprognostic (1.90e-2)" "unprognostic (1.33e-2)" "unprognostic (9.00e-2)" "unprognostic (3.35e-1)" "unprognostic (1.88e-1)" "unprognostic (6.48e-2)" "unprognostic (2.03e-1)" "unprognostic (5.70e-2)" "unprognostic (1.60e-1)" "unprognostic (3.16e-2)" "unprognostic (1.15e-1)" "unprognostic (7.45e-2)" "unprognostic (2.30e-1)" "unprognostic (2.52e-2)" "unprognostic (4.41e-2)" SLC39A4 "AEZ, AWMS2, ZIP4" ENSG00000147804 "Solute carrier family 39 member 4" Q6P5W5 8 144409742-144416844 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "intestine: 82.8" "Cell type enhanced" "Detected in many" "Enteric transient amplifying cells: 59.5;Enterocytes: 237.9;Gastric chief cells: 56.8;Gastric progenitor cells: 103.8;Oocytes: 179.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 77: Intestine - Digestion" "Cluster 53: Neurons - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 1: Enterocytes - Absorption and Digestion" 57 "unprognostic (2.28e-1)" "unprognostic (2.71e-1)" "unprognostic (2.65e-3)" "unprognostic (5.74e-2)" "unprognostic (1.10e-1)" "unprognostic (6.12e-2)" "unprognostic (1.01e-1)" "unprognostic (1.41e-1)" "unprognostic (1.87e-3)" "unprognostic (2.73e-2)" "unprognostic (2.24e-2)" "unprognostic (4.55e-2)" "unprognostic (4.30e-3)" "unprognostic (4.93e-1)" "unprognostic (2.46e-1)" "unprognostic (1.80e-2)" "unprognostic (2.50e-2)" "unprognostic (7.12e-2)" "unprognostic (9.76e-3)" "unprognostic (2.23e-2)" "unprognostic (1.22e-1)" "unprognostic (2.88e-3)" "unprognostic (2.90e-2)" "unprognostic (2.58e-1)" "unprognostic (2.87e-3)" "unprognostic (2.63e-2)" SLC39A5 ENSG00000139540 "Solute carrier family 39 member 5" Q6ZMH5 12 56230049-56237846 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 32 "intestine: 223.1;kidney: 102.5;liver: 165.6;pancreas: 291.7" "Cell type enriched" "Detected in some" 4 "Enterocytes: 744.8" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 64.0" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "colorectal cancer: 20.4;Gastric cancer: 12.0;liver cancer: 22.1" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Region enhanced" "Detected in single" "basal ganglia: 1.1" "Not detected" "Not detected" HPA018423 Approved Nucleoplasm,Vesicles NA NA "Cluster 60: Stomach - Digestion" "Cluster 15: Non-specific - Transcription" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 1: Enterocytes - Absorption and Digestion" 13 Vesicles Nucleoplasm "HPA018423: " "unprognostic (1.41e-2)" "unprognostic (9.70e-2)" "unprognostic (2.65e-1)" "potential prognostic favorable (3.66e-9)" "unprognostic (3.93e-3)" "unprognostic (1.95e-2)" "unprognostic (1.45e-1)" "unprognostic (2.65e-2)" "unprognostic (1.90e-1)" "unprognostic (7.88e-2)" "unprognostic (3.91e-2)" "unprognostic (2.57e-2)" "unprognostic (6.93e-2)" "unprognostic (4.73e-1)" "unprognostic (2.92e-1)" "unprognostic (2.28e-1)" SLC39A6 LIV-1 ENSG00000141424 "Solute carrier family 39 member 6" Q13433 18 36108531-36129385 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 533.6;Prostatic club cells: 181.0;Prostatic glandular cells: 585.7" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Breast Invasive Carcinoma (TCGA): 645.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Prostate - Prostate glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042377 Approved Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 55: Breast - Lactation" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 27: Breast cancer - Unknown function" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 26 Cytosol "Nucleoplasm, Plasma membrane" "HPA042377: " "unprognostic (1.40e-2)" "unprognostic (4.00e-1)" "unprognostic (7.10e-2)" "unprognostic (4.57e-3)" "unprognostic (1.23e-1)" "unprognostic (4.23e-2)" "unprognostic (1.04e-1)" "unprognostic (3.70e-2)" "unprognostic (2.30e-2)" "unprognostic (1.95e-2)" "unprognostic (1.56e-3)" "unprognostic (2.68e-2)" "unprognostic (1.28e-1)" "unprognostic (2.85e-3)" "unprognostic (2.26e-2)" "unprognostic (7.63e-2)" "unprognostic (1.71e-2)" "unprognostic (5.97e-2)" "unprognostic (1.18e-3)" "unprognostic (1.68e-1)" "unprognostic (6.52e-2)" "unprognostic (1.77e-1)" "unprognostic (3.16e-1)" "unprognostic (1.33e-1)" "unprognostic (3.10e-1)" "unprognostic (2.73e-1)" "unprognostic (2.40e-1)" "unprognostic (3.81e-1)" "unprognostic (5.49e-2)" "unprognostic (6.82e-2)" "unprognostic (1.10e-1)" SLC39A7 "D6S2244E, H2-KE4, HKE4, KE4, RING5, ZIP7" ENSG00000112473 "Solute carrier family 39 member 7" Q92504 6 33200305-33204439 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 33.5;Prostatic glandular cells: 34.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053999 Approved Supported "Nucleoplasm,Endoplasmic reticulum" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 70: Non-specific - Protein processing" "Cluster 44: Non-specific - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 78: Plasma cells - Antibody production & ER-stress response" 39 "Endoplasmic reticulum" Nucleoplasm "HPA053999: " "unprognostic (8.73e-2)" "unprognostic (9.11e-3)" "unprognostic (4.26e-1)" "unprognostic (2.14e-2)" "unprognostic (9.00e-2)" "unprognostic (6.02e-3)" "unprognostic (6.38e-2)" "unprognostic (2.50e-2)" "unprognostic (2.48e-1)" "unprognostic (1.01e-2)" "potential prognostic favorable (3.46e-6)" "unprognostic (1.45e-1)" "unprognostic (2.54e-2)" "unprognostic (1.20e-3)" "potential prognostic unfavorable (1.02e-4)" "unprognostic (1.09e-1)" "unprognostic (1.42e-2)" "unprognostic (6.99e-2)" "unprognostic (9.87e-2)" "unprognostic (1.10e-1)" "unprognostic (2.58e-1)" "unprognostic (1.95e-1)" "unprognostic (9.44e-2)" "unprognostic (3.69e-1)" "unprognostic (5.62e-2)" "unprognostic (6.67e-2)" "unprognostic (2.17e-1)" "unprognostic (1.29e-1)" "unprognostic (1.38e-1)" "potential prognostic unfavorable (1.27e-4)" "unprognostic (7.90e-2)" SLC39A8 BIGM103 ENSG00000138821 "Solute carrier family 39 member 8" Q9C0K1 4 102251080-102431258 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Symport, Transport, Zinc transport" "Congenital disorder of glycosylation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 58.7;salivary gland: 44.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 1203.0;Alveolar cells type 2: 900.0;Breast lactating cells: 340.2;Epicardial cells: 1953.5;Extravillous trophoblasts: 366.0;Mesothelial cells: 510.5;monocytes: 365.1;Salivary acinar cells: 369.4;Transitional alveolar cells: 421.0" "Cell type enriched" "Detected in all" 7 "endothelial cell: 341.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Pituitary gland - Corticotropes, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038832, HPA038833" Approved NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 60: Stomach - Digestion" "Cluster 47: Endothelial cells - Vasculature" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 12 "HPA038832: , HPA038833: " "unprognostic (8.38e-2)" "unprognostic (2.89e-3)" "unprognostic (3.04e-1)" "potential prognostic unfavorable (2.10e-4)" "unprognostic (7.02e-2)" "unprognostic (1.48e-1)" "unprognostic (4.87e-2)" "unprognostic (4.14e-3)" "unprognostic (4.21e-2)" "potential prognostic unfavorable (8.60e-4)" "potential prognostic favorable (1.08e-6)" "unprognostic (8.45e-3)" "potential prognostic favorable (2.78e-4)" "unprognostic (1.45e-1)" "unprognostic (1.65e-1)" "unprognostic (8.47e-3)" "unprognostic (1.62e-2)" "unprognostic (2.08e-3)" "unprognostic (1.36e-1)" "unprognostic (3.83e-1)" "unprognostic (2.98e-2)" "unprognostic (2.98e-3)" "unprognostic (7.94e-2)" "unprognostic (3.28e-2)" "unprognostic (2.33e-1)" "unprognostic (3.77e-2)" "unprognostic (1.27e-3)" "unprognostic (2.84e-1)" "unprognostic (3.99e-2)" "unprognostic (4.71e-2)" "unprognostic (1.93e-1)" SLC39A9 FLJ11274 ENSG00000029364 "Solute carrier family 39 member 9" Q9NUM3 14 69398015-69462390 "Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007921, HPA075390" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 8: Non-specific - Secretory pathway" 38 "Endoplasmic reticulum" "HPA007921: , HPA075390: " "unprognostic (2.78e-1)" "unprognostic (1.34e-1)" "unprognostic (1.18e-1)" "unprognostic (1.45e-1)" "unprognostic (1.72e-1)" "unprognostic (9.73e-2)" "unprognostic (1.88e-1)" "unprognostic (7.63e-2)" "unprognostic (2.98e-2)" "unprognostic (3.61e-1)" "potential prognostic favorable (1.71e-8)" "unprognostic (2.21e-3)" "unprognostic (1.09e-1)" "unprognostic (7.68e-2)" "unprognostic (1.04e-1)" "unprognostic (2.65e-3)" "unprognostic (2.98e-2)" "unprognostic (5.91e-3)" "unprognostic (2.87e-1)" "unprognostic (1.51e-1)" "unprognostic (9.69e-3)" "unprognostic (2.52e-1)" "unprognostic (5.24e-1)" "unprognostic (8.29e-2)" "unprognostic (2.53e-1)" "unprognostic (1.62e-1)" "unprognostic (1.21e-1)" "unprognostic (7.23e-2)" "unprognostic (9.09e-2)" "unprognostic (4.70e-2)" "unprognostic (2.31e-1)" SLC3A1 "ATR1, CSNU1, D2H, NBAT, RBAT" ENSG00000138079 "Solute carrier family 3 member 1" Q07837 2 44275458-44321494 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Cystinuria, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 128.1;kidney: 604.7;pancreas: 205.1" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 201.4;Endometrial glandular cells: 59.3;Endometrial luminal cells: 152.0;Enterocytes: 206.1;Epididymal efferent duct absorptive cells: 95.8;Loop of henle epithelial cells: 122.6;Oocytes: 170.4;Pancreatic duct cells: 200.2;Proximal tubule cells: 272.8;Renal collecting duct intercalated cells: 82.0;Renal connecting tubule cells: 115.3" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" 8 "Kidney Renal Clear Cell Carcinoma (TCGA): 524.6;Kidney Renal Papillary Cell Carcinoma (TCGA): 490.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 15.1;Kidney cancer: 17.1" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA038360, HPA071102" Enhanced Approved "Nuclear bodies,Mitochondria" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 72: Kidney - Transmembrane transport" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 88: Proximal tubular cells - Transmembrane transport" 1 Mitochondria "Nuclear bodies" "HPA038360: , HPA071102: " "unprognostic (1.56e-1)" "unprognostic (2.24e-1)" "unprognostic (9.96e-2)" "unprognostic (4.01e-2)" "unprognostic (3.71e-2)" "unprognostic (2.91e-3)" "validated prognostic favorable (7.46e-10)" "validated prognostic favorable (1.68e-5)" "potential prognostic favorable (1.19e-4)" "unprognostic (2.31e-2)" "unprognostic (1.38e-2)" "unprognostic (3.18e-1)" "unprognostic (4.55e-2)" "unprognostic (1.60e-1)" "unprognostic (8.02e-2)" "unprognostic (1.43e-1)" "unprognostic (7.63e-2)" "unprognostic (8.74e-2)" "unprognostic (2.30e-2)" "unprognostic (9.82e-2)" "unprognostic (1.34e-2)" "unprognostic (3.40e-3)" SLC3A2 "4F2, 4F2HC, 4T2HC, CD98, CD98HC, MDU1, NACAE" ENSG00000168003 "Solute carrier family 3 member 2" P08195 11 62856004-62888880 "Cancer-related genes, CD markers, Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Host cell receptor for virus entry, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 400.9;Retinal pigment epithelial cells: 443.3;Syncytiotrophoblasts: 1124.0" "Cell type enhanced" "Detected in all" "endothelial cell: 215.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Kidney - Proximal tubular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010455, HPA017980" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 61000000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." 58 "Nucleoplasm, Plasma membrane" "CAB010455: , HPA017980: " "unprognostic (2.19e-2)" "unprognostic (5.47e-2)" "unprognostic (1.54e-1)" "unprognostic (1.51e-1)" "unprognostic (8.33e-2)" "unprognostic (3.01e-2)" "unprognostic (5.63e-2)" "unprognostic (1.12e-1)" "unprognostic (1.49e-3)" "unprognostic (2.57e-1)" "unprognostic (1.14e-3)" "unprognostic (5.59e-2)" "unprognostic (1.40e-1)" "unprognostic (1.45e-2)" "unprognostic (4.98e-2)" "potential prognostic unfavorable (7.08e-5)" "unprognostic (1.61e-2)" "unprognostic (4.15e-1)" "unprognostic (2.73e-1)" "unprognostic (7.89e-2)" "unprognostic (6.26e-2)" "unprognostic (5.35e-2)" "unprognostic (1.10e-2)" "unprognostic (1.61e-1)" "unprognostic (2.71e-1)" "unprognostic (2.46e-2)" "unprognostic (2.71e-1)" "unprognostic (6.16e-2)" "unprognostic (5.98e-2)" "unprognostic (1.49e-1)" "unprognostic (1.74e-2)" SLC40A1 "FPN1, HFE4, IREG1, MTP1, SLC11A3" ENSG00000138449 "Solute carrier family 40 member 1" Q9NP59 2 189560590-189583758 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Iron transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Kupffer cells: 3944.9;Platelets: 987.0;Syncytiotrophoblasts: 3638.1" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 73.7;fibroblast: 99.8;pericyte: 129.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 327.7" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Leukemia: 75.6;liver cancer: 50.9" "Adrenal gland - Adrenal cortex cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065634 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 3 "Plasma membrane, Cytosol" Nucleoplasm "HPA065634: " "unprognostic (9.99e-2)" "unprognostic (2.41e-2)" "unprognostic (2.35e-1)" "unprognostic (1.10e-1)" "unprognostic (4.95e-2)" "unprognostic (4.78e-3)" "unprognostic (1.87e-2)" "unprognostic (8.33e-2)" "unprognostic (4.26e-2)" "unprognostic (7.36e-2)" "validated prognostic favorable (1.92e-12)" "validated prognostic favorable (6.11e-4)" "unprognostic (3.51e-1)" "unprognostic (1.66e-1)" "potential prognostic favorable (7.30e-5)" "unprognostic (1.24e-1)" "unprognostic (1.49e-1)" "unprognostic (2.84e-1)" "unprognostic (2.39e-2)" "unprognostic (1.18e-1)" "unprognostic (1.78e-1)" "unprognostic (8.66e-2)" "potential prognostic favorable (2.70e-4)" "unprognostic (1.18e-1)" "unprognostic (2.39e-2)" "unprognostic (3.23e-2)" "unprognostic (4.88e-2)" "unprognostic (3.65e-1)" "unprognostic (4.88e-2)" "unprognostic (6.15e-2)" "unprognostic (2.22e-1)" SLC41A1 MgtE ENSG00000133065 "Solute carrier family 41 member 1" Q8IVJ1 1 205789094-205813748 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Disease variant, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 93.1;pancreas: 58.1;tongue: 71.0" "Cell type enhanced" "Detected in many" "Breast lactating cells: 91.0;Cardiomyocytes: 351.3;Choroid plexus epithelial cells: 114.1" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 97.8;ependymal cell: 81.4;fibroblast: 124.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Minor Salivary Gland - Endothelial cells, Skeletal muscle - Skeletal myocytes, Spleen - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014721, HPA015138" Uncertain Approved Mitochondria NA NA "Cluster 24: Non-specific - Transcription" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 55: Lymphoma - Immune response" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 29 Mitochondria "HPA014721: , HPA015138: " "unprognostic (1.33e-1)" "unprognostic (2.46e-1)" "unprognostic (1.39e-2)" "potential prognostic unfavorable (5.99e-4)" "unprognostic (1.00e-1)" "unprognostic (6.19e-2)" "unprognostic (4.26e-2)" "unprognostic (2.97e-1)" "unprognostic (1.34e-1)" "unprognostic (9.94e-2)" "potential prognostic favorable (7.98e-8)" "unprognostic (2.73e-2)" "unprognostic (1.26e-2)" "unprognostic (2.01e-2)" "unprognostic (3.03e-2)" "unprognostic (1.17e-1)" "unprognostic (2.17e-2)" "unprognostic (5.67e-2)" "unprognostic (9.80e-3)" "unprognostic (3.27e-2)" "unprognostic (3.27e-2)" "unprognostic (1.32e-1)" "unprognostic (9.02e-2)" "unprognostic (6.68e-2)" "unprognostic (9.14e-2)" "unprognostic (5.13e-2)" "unprognostic (8.45e-2)" "unprognostic (1.09e-1)" "unprognostic (1.94e-1)" "unprognostic (1.31e-1)" "unprognostic (1.84e-1)" SLC41A2 DKFZP434K0427 ENSG00000136052 "Solute carrier family 41 member 2" Q96JW4 12 104801801-104958744 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 86.0" "Cell type enhanced" "Detected in many" "Foveolar cells: 252.8;Mucous neck cells: 284.8;Sertoli cells: 250.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "myeloid DC: 3.1;plasmacytoid DC: 9.1" "Lineage enriched" "Detected in single" 12 "dendritic cells: 9.1" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038658 Approved NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 1: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 82: Dendritic cells - Antigen presentation" 29 "HPA038658: " "unprognostic (3.21e-2)" "unprognostic (1.11e-2)" "unprognostic (6.31e-2)" "unprognostic (1.66e-2)" "unprognostic (1.34e-2)" "unprognostic (1.48e-1)" "unprognostic (2.43e-2)" "unprognostic (1.40e-3)" "unprognostic (9.65e-2)" "unprognostic (3.39e-2)" "potential prognostic favorable (3.42e-5)" "unprognostic (1.03e-1)" "unprognostic (2.53e-2)" "potential prognostic favorable (5.28e-4)" "unprognostic (1.83e-3)" "unprognostic (1.52e-2)" "unprognostic (2.46e-3)" "unprognostic (2.83e-3)" "unprognostic (1.04e-1)" "unprognostic (9.14e-3)" "unprognostic (7.05e-2)" "unprognostic (4.15e-2)" "unprognostic (2.76e-2)" "unprognostic (1.25e-1)" "unprognostic (1.05e-1)" "unprognostic (2.87e-2)" "unprognostic (1.69e-1)" "unprognostic (2.74e-1)" "unprognostic (4.84e-2)" "unprognostic (4.51e-3)" "unprognostic (2.37e-1)" SLC41A3 FLJ20473 ENSG00000114544 "Solute carrier family 41 member 3" Q96GZ6 3 126006357-126101561 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045847 Approved Supported "Plasma membrane" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 63: Non-specific - Protein processing" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 9 "Plasma membrane" "HPA045847: " "unprognostic (1.97e-3)" "unprognostic (2.50e-2)" "unprognostic (2.59e-1)" "unprognostic (1.34e-1)" "unprognostic (5.82e-2)" "unprognostic (2.55e-2)" "unprognostic (1.99e-1)" "potential prognostic favorable (5.85e-4)" "unprognostic (1.13e-1)" "unprognostic (7.84e-2)" "potential prognostic favorable (1.15e-4)" "unprognostic (7.32e-2)" "potential prognostic favorable (4.76e-5)" "potential prognostic unfavorable (9.97e-8)" "unprognostic (1.40e-3)" "unprognostic (1.15e-1)" "unprognostic (1.93e-2)" "unprognostic (1.40e-1)" "unprognostic (1.15e-1)" "potential prognostic unfavorable (8.21e-5)" "unprognostic (7.57e-2)" "unprognostic (1.81e-1)" "unprognostic (1.33e-1)" "unprognostic (2.23e-1)" "unprognostic (1.65e-1)" "unprognostic (4.53e-3)" "unprognostic (1.97e-1)" "unprognostic (4.04e-1)" "unprognostic (8.33e-2)" "unprognostic (1.61e-1)" "unprognostic (3.90e-1)" SLC43A1 "PB39, POV1, R00504" ENSG00000149150 "Solute carrier family 43 member 1" O75387 11 57484534-57515780 "Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "liver: 121.8;pancreas: 219.9" "Cell type enhanced" "Detected in many" "Cholangiocytes: 46.0;Distal convoluted tubule cells: 39.9;Early spermatids: 32.7;Erythrocyte progenitors: 79.4;Gastric chief cells: 43.7;Hepatic stellate cells: 32.3;Hepatocytes: 167.6;Pancreatic acinar cells: 97.4" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 82.5;Testicular Germ Cell Tumor (TCGA): 79.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Stomach - Chief cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018813, HPA018826" Enhanced Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 8: Pancreas - Proteolysis" "Cluster 53: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 93: Hepatocytes - Bile production & excretion" 2 "Golgi apparatus, Vesicles, Plasma membrane" "HPA018813: , HPA018826: " "unprognostic (9.41e-3)" "unprognostic (1.57e-1)" "unprognostic (8.20e-2)" "unprognostic (1.59e-3)" "unprognostic (1.25e-1)" "unprognostic (1.98e-1)" "unprognostic (4.80e-2)" "unprognostic (5.23e-3)" "unprognostic (1.96e-1)" "unprognostic (1.19e-1)" "unprognostic (3.57e-2)" "unprognostic (8.05e-2)" "unprognostic (4.35e-3)" "unprognostic (6.01e-2)" "unprognostic (9.92e-2)" "unprognostic (9.85e-3)" "potential prognostic unfavorable (1.04e-4)" "unprognostic (2.80e-1)" "unprognostic (9.84e-2)" "unprognostic (4.85e-2)" "unprognostic (4.46e-2)" "unprognostic (1.51e-1)" "unprognostic (2.35e-2)" "unprognostic (2.20e-1)" "unprognostic (1.13e-1)" "unprognostic (1.48e-1)" "unprognostic (1.72e-2)" "unprognostic (6.02e-3)" "unprognostic (1.06e-1)" "potential prognostic unfavorable (2.26e-4)" "unprognostic (5.10e-2)" SLC43A2 MGC34680 ENSG00000167703 "Solute carrier family 43 member 2" Q8N370 17 1569268-1628886 "Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 55.0" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 107.8;Epididymal clear cells: 49.0;Loop of henle epithelial cells: 143.7;Microglia: 72.4;Proximal tubule cells: 181.1;Renal collecting duct intercalated cells: 394.5;Renal collecting duct principal cells: 56.4;Renal connecting tubule cells: 121.1;Syncytiotrophoblasts: 102.1" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 5 "Kidney Chromophobe (TCGA): 49.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 15.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose visceral - Macrophages, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021564 Enhanced NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 24: Non-specific - Transcription" "Cluster 24: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 6 "HPA021564: " "unprognostic (1.32e-2)" "unprognostic (3.61e-2)" "unprognostic (7.80e-2)" "unprognostic (1.07e-2)" "unprognostic (3.02e-1)" "unprognostic (1.38e-1)" "unprognostic (1.89e-2)" "unprognostic (2.33e-1)" "unprognostic (5.72e-2)" "unprognostic (5.66e-2)" "potential prognostic favorable (1.52e-6)" "unprognostic (1.76e-2)" "unprognostic (5.48e-2)" "unprognostic (3.46e-2)" "unprognostic (9.75e-2)" "unprognostic (3.32e-2)" "unprognostic (1.73e-1)" "unprognostic (2.16e-3)" "unprognostic (3.92e-1)" "unprognostic (5.10e-2)" "unprognostic (1.44e-1)" "unprognostic (1.03e-2)" "unprognostic (2.43e-1)" "unprognostic (3.20e-1)" "unprognostic (1.70e-1)" "unprognostic (2.31e-1)" "unprognostic (1.37e-1)" "unprognostic (2.93e-1)" "unprognostic (1.86e-3)" "unprognostic (1.18e-1)" "unprognostic (6.04e-2)" SLC43A3 "DKFZp762A227, Eeg1, FOAP-13, PRO1659, SEEEG-1" ENSG00000134802 "Solute carrier family 43 member 3" Q8NBI5 11 57406954-57427580 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 134.9" "Cell type enhanced" "Detected in some" "cDC: 4.9;Epicardial cells: 6.8;Erythrocyte progenitors: 11.4;Lymphatic endothelial cells: 4.7;Mast cells: 6.8;Megakaryocyte progenitors: 4.9;Microglia: 5.6;monocytes: 5.8;Myosatellite cells: 6.3;pDCs: 6.4" "Cell type enhanced" "Detected in some" "fibroblast: 9.6;pericyte: 18.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 105.9;intermediate monocyte: 127.2;myeloid DC: 85.9;non-classical monocyte: 147.3;plasmacytoid DC: 86.0" "Group enriched" "Detected in all" 4 "dendritic cells: 86.0;monocytes: 147.3" "Cancer enhanced" "Detected in many" "skin cancer: 220.6" "Colon - Endothelial cells, Pituitary gland - Endothelial cells" "Region enhanced" "Detected in many" "olfactory bulb: 10.3" "Low region specificity" "Detected in all" "HPA030551, HPA077244" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA Yes "Cluster 10: Non-specific - Membrane trafficking" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 12: Non-specific - Vasculature" "Cluster 69: Skin cancer - ECM organization" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 15 Vesicles "Nucleoplasm, Plasma membrane" "HPA030551: , HPA077244: " "unprognostic (9.64e-2)" "unprognostic (1.44e-1)" "unprognostic (1.47e-1)" "unprognostic (1.86e-2)" "unprognostic (2.24e-2)" "unprognostic (8.59e-2)" "unprognostic (2.24e-3)" "potential prognostic unfavorable (1.70e-4)" "unprognostic (1.98e-2)" "unprognostic (8.92e-2)" "unprognostic (1.43e-2)" "unprognostic (6.76e-2)" "unprognostic (1.07e-1)" "unprognostic (2.21e-1)" "unprognostic (1.22e-1)" "unprognostic (1.10e-1)" "unprognostic (6.87e-3)" "unprognostic (1.53e-2)" "unprognostic (1.78e-2)" "unprognostic (1.68e-2)" "unprognostic (1.61e-1)" "unprognostic (1.23e-1)" "unprognostic (2.95e-1)" "unprognostic (8.53e-2)" "unprognostic (1.79e-1)" "unprognostic (6.90e-3)" "unprognostic (2.36e-1)" "unprognostic (1.47e-1)" "unprognostic (2.90e-1)" "unprognostic (2.18e-2)" "unprognostic (2.66e-2)" SLC44A1 "CD92, CDW92, CHTL1, CTL1" ENSG00000070214 "Solute carrier family 44 member 1" Q8WWI5 9 105244622-105439171 "CD markers, Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Transport" Neurodegeneration "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 229.5" "Group enriched" "Detected in all" 4 "Megakaryocyte progenitors: 1004.7;Oligodendrocytes: 3391.3" "Group enriched" "Detected in all" 7 "committed oligodendrocyte precursor: 2570.1;oligodendrocyte: 4379.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 8.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064714, HPA074007" Enhanced Supported Nucleoplasm,Mitochondria NA NA 93000 "Cluster 14: Non-specific - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 80: Oligodendrocytes - Myelination" 2 Mitochondria Nucleoplasm "HPA064714: , HPA074007: " "unprognostic (2.83e-2)" "unprognostic (1.04e-1)" "unprognostic (3.82e-2)" "unprognostic (1.77e-2)" "unprognostic (1.49e-1)" "unprognostic (1.50e-1)" "unprognostic (9.56e-2)" "unprognostic (4.94e-2)" "unprognostic (1.03e-1)" "unprognostic (1.30e-1)" "validated prognostic favorable (3.88e-10)" "validated prognostic favorable (1.84e-4)" "unprognostic (7.81e-3)" "unprognostic (2.88e-2)" "unprognostic (1.59e-3)" "unprognostic (2.75e-3)" "unprognostic (6.35e-3)" "unprognostic (1.01e-1)" "unprognostic (9.57e-2)" "unprognostic (5.63e-3)" "potential prognostic unfavorable (6.05e-4)" "potential prognostic unfavorable (9.71e-4)" "unprognostic (2.46e-2)" "unprognostic (1.60e-1)" "unprognostic (1.22e-1)" "unprognostic (2.89e-2)" "unprognostic (2.63e-1)" "unprognostic (1.21e-1)" "unprognostic (2.38e-1)" "unprognostic (1.59e-1)" "unprognostic (3.48e-1)" SLC44A2 CTL2 ENSG00000129353 "Solute carrier family 44 member 2" Q8IWA5 19 10602457-10644557 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 222.9;Esophageal apical cells: 214.5;Extravillous trophoblasts: 356.1;Migrating cytotrophoblasts: 269.7;Neutrophils: 356.3;Platelets: 377.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003228, HPA070799" Approved Approved "Vesicles,Cell Junctions" NA NA 2600000 "Cluster 35: Neutrophils - Protein binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 24: Neutrophils - Innate immunity signal integration" 5 "Vesicles, Cell Junctions" "HPA003228: , HPA070799: " "unprognostic (1.41e-1)" "unprognostic (6.43e-2)" "unprognostic (8.73e-2)" "unprognostic (4.57e-2)" "unprognostic (2.52e-1)" "unprognostic (5.55e-3)" "unprognostic (4.42e-2)" "unprognostic (9.17e-3)" "unprognostic (2.70e-2)" "unprognostic (1.51e-1)" "validated prognostic favorable (3.19e-7)" "validated prognostic favorable (1.84e-7)" "unprognostic (6.82e-2)" "unprognostic (1.54e-1)" "unprognostic (2.07e-3)" "unprognostic (4.67e-2)" "unprognostic (1.22e-1)" "unprognostic (4.20e-2)" "unprognostic (4.40e-2)" "unprognostic (1.93e-1)" "unprognostic (2.31e-2)" "potential prognostic unfavorable (7.30e-4)" "unprognostic (8.46e-2)" "unprognostic (1.66e-1)" "unprognostic (2.50e-1)" "unprognostic (3.24e-1)" "unprognostic (2.62e-1)" "unprognostic (2.79e-1)" "unprognostic (2.93e-1)" "unprognostic (2.14e-1)" "unprognostic (2.04e-1)" SLC44A3 "CTL3, MGC45474" ENSG00000143036 "Solute carrier family 44 member 3" Q8N4M1 1 94820342-94895246 "Cancer-related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 257.5;Somatotrophs: 282.3;Thyrotrophs: 197.9" "Cell type enhanced" "Detected in many" "astrocyte: 57.9;Bergmann glia: 32.4;fibroblast: 30.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "MAIT T-cell: 1.8" "Lineage enriched" "Detected in single" 18 "T-cells: 1.8" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 50.1" "Lung - Alveolar cells type 1, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Testis - Late spermatids" "Region enhanced" "Detected in single" "pons and medulla: 1.1" "Low region specificity" "Detected in all" HPA047433 Enhanced NA NA "Cluster 1: T-cells - Unknown function" "Cluster 60: Stomach - Digestion" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 1 "HPA047433: " "unprognostic (3.24e-3)" "unprognostic (1.90e-1)" "unprognostic (1.39e-2)" "unprognostic (9.49e-2)" "unprognostic (4.39e-3)" "unprognostic (4.44e-2)" "unprognostic (8.83e-3)" "unprognostic (2.54e-3)" "unprognostic (2.35e-1)" "unprognostic (6.25e-2)" "potential prognostic favorable (1.14e-5)" "unprognostic (2.57e-3)" "unprognostic (6.25e-3)" "unprognostic (1.91e-1)" "unprognostic (3.13e-2)" "unprognostic (3.72e-2)" "unprognostic (5.77e-3)" "unprognostic (8.81e-2)" "unprognostic (3.92e-2)" "unprognostic (7.71e-2)" "unprognostic (1.12e-1)" "unprognostic (1.01e-1)" "unprognostic (2.50e-2)" "unprognostic (1.31e-1)" "unprognostic (4.28e-2)" "unprognostic (1.32e-2)" "unprognostic (1.36e-1)" "unprognostic (9.30e-2)" "unprognostic (1.08e-1)" "unprognostic (1.23e-1)" "unprognostic (5.71e-3)" SLC44A4 "C6orf29, CTL4, DFNA72, FLJ14491, NG22, TPPT" ENSG00000204385 "Solute carrier family 44 member 4" Q53GD3 6 31863192-31879046 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Transport" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 123.7;prostate: 80.5;stomach 1: 79.1" "Cell type enhanced" "Detected in some" "Conjunctival goblet cells: 15.5;Endometrial ciliated cells: 22.5;Endometrial secretory cells: 13.9;Fallopian tube ciliated cells: 38.7;Papillary tip epithelial cells: 53.4;Prostatic club cells: 28.8;Prostatic glandular cells: 35.8;Proximal tubule cells: 28.8;Renal collecting duct principal cells: 52.8;Respiratory ciliated cells: 31.1" "Cell type enriched" "Detected in single" 18 "ependymal cell: 4.9" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 129.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 10.7;Gastric cancer: 10.1;prostate cancer: 27.9" "Breast - Breast glandular cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Pituitary gland - Corticotropes, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046977, HPA054176" Enhanced NA NA "Cluster 77: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" "HPA046977: , HPA054176: " "unprognostic (7.96e-3)" "unprognostic (4.41e-2)" "unprognostic (2.28e-1)" "unprognostic (2.76e-2)" "unprognostic (2.96e-2)" "unprognostic (1.26e-1)" "unprognostic (7.74e-3)" "potential prognostic favorable (1.23e-4)" "unprognostic (2.73e-2)" "unprognostic (3.48e-3)" "potential prognostic unfavorable (1.39e-5)" "unprognostic (3.17e-2)" "unprognostic (1.42e-1)" "unprognostic (1.80e-1)" "unprognostic (1.56e-1)" "unprognostic (1.71e-1)" "unprognostic (3.10e-2)" "unprognostic (2.05e-2)" "unprognostic (1.17e-1)" "unprognostic (2.40e-1)" "unprognostic (1.84e-1)" "unprognostic (2.78e-2)" "unprognostic (1.98e-1)" "unprognostic (2.78e-2)" "unprognostic (1.66e-2)" SLC44A5 "CTL5, MGC34032" ENSG00000137968 "Solute carrier family 44 member 5" Q8NCS7 1 75202129-75611114 "Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 10.1" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 241.9;Brain inhibitory neurons: 276.3;Early spermatids: 278.8;Gonadotrophs: 918.5;Granulosa cells: 271.7;Lactotrophs: 168.0;Late primary spermatocytes: 173.3;Oligodendrocyte progenitor cells: 366.4;Other brain neurons: 367.5;Thymic myoid cells: 284.2;Thyrotrophs: 318.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA047455, HPA051011" Uncertain Approved Cytosol NA NA "Cluster 58: Skin - Keratinization" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 56: Non-specific - Sensory perception" "Cluster 109: Neurons - Neuronal signaling" 11 Cytosol "HPA047455: , HPA051011: " "unprognostic (2.62e-2)" "unprognostic (5.08e-2)" "unprognostic (3.51e-2)" "unprognostic (3.09e-1)" "unprognostic (2.11e-1)" "unprognostic (3.72e-1)" "unprognostic (3.78e-1)" "unprognostic (1.05e-3)" "unprognostic (2.12e-1)" "unprognostic (2.93e-2)" "unprognostic (1.22e-2)" "unprognostic (1.37e-2)" "unprognostic (5.53e-3)" "unprognostic (1.36e-1)" "unprognostic (1.23e-1)" "unprognostic (4.34e-2)" "unprognostic (4.02e-2)" "unprognostic (1.74e-2)" "unprognostic (1.52e-2)" "unprognostic (1.32e-2)" "unprognostic (1.77e-2)" "unprognostic (1.04e-1)" "unprognostic (1.79e-1)" "unprognostic (2.97e-2)" "unprognostic (9.28e-3)" "unprognostic (4.72e-2)" "unprognostic (2.24e-2)" "unprognostic (2.89e-2)" SLC45A1 DNB5 ENSG00000162426 "Solute carrier family 45 member 1" Q9Y2W3 1 8318114-8344167 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Sugar transport, Symport, Transport" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.3" "Cell type enriched" "Detected in many" 5 "Podocytes: 114.9" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 6.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "non-classical monocyte: 4.0" "Lineage enriched" "Detected in single" 5 "monocytes: 4.0" "Cancer enriched" "Detected in some" 5 "Rhabdoid: 9.6" "Kidney - Podocytes, Prostate - Smooth muscle cells, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078818 Enhanced NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 64: Non-specific - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 57: Podocytes - Glomerular filtration" "HPA078818: " "unprognostic (3.41e-2)" "unprognostic (1.97e-1)" "unprognostic (2.18e-3)" "unprognostic (7.87e-2)" "potential prognostic favorable (1.04e-4)" "unprognostic (1.13e-1)" "unprognostic (3.31e-1)" "unprognostic (1.06e-1)" "unprognostic (2.28e-3)" "unprognostic (6.58e-2)" "unprognostic (2.11e-1)" "unprognostic (9.41e-3)" "unprognostic (5.55e-2)" SLC45A2 "AIM-1, MATP, OCA4" ENSG00000164175 "Solute carrier family 45 member 2" Q9UMX9 5 33944623-33984693 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Melanin biosynthesis, Sensory transduction, Symport, Transport, Vision" "Albinism, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "liver: 1.2;testis: 1.0" "Cell type enhanced" "Detected in some" "Ependymal cells: 11.0;Loop of henle epithelial cells: 7.6;Melanocytes: 36.5;Other brain neurons: 7.9;Retinal pigment epithelial cells: 51.2" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in some" 25 "Skin Cutaneous Melanoma (TCGA): 97.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 111 "skin cancer: 163.1" "Skin - Melanocytes, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 47: Testis - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 61: Schwann cells & Melanocytes - Mixed function" 2 "unprognostic (8.97e-3)" "unprognostic (1.61e-2)" "unprognostic (2.60e-2)" "unprognostic (1.95e-1)" SLC45A3 "IPCA-2, IPCA-6, IPCA-8, PCANAP2, PCANAP6, PCANAP8, prostein" ENSG00000158715 "Solute carrier family 45 member 3" Q96JT2 1 205657851-205680509 "Cancer-related genes, Predicted membrane proteins, Transporters" "Symport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "prostate: 288.1" "Cell type enriched" "Detected in many" 7 "Prostatic glandular cells: 561.5" "Group enriched" "Detected in some" 4 "committed oligodendrocyte precursor: 27.0;oligodendrocyte: 66.9" "Cancer enriched" "Detected in many" 57 "Prostate Adenocarcinoma (TCGA): 668.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 382 "basophil: 40.6" "Lineage enriched" "Detected in single" 382 "granulocytes: 40.6" "Cancer enriched" "Detected in all" 7 "prostate cancer: 115.8" "Breast - Breast myoepithelial cells, Prostate - Prostate glandular cells, Spleen - B-cells (Spleen), Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA019073, HPA019075" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 1 Vesicles Nucleoplasm "HPA019073: , HPA019075: " "unprognostic (7.01e-2)" "unprognostic (1.04e-1)" "unprognostic (1.58e-3)" "unprognostic (1.34e-2)" "unprognostic (4.91e-3)" "unprognostic (6.69e-2)" "unprognostic (7.00e-2)" "unprognostic (1.45e-1)" "unprognostic (6.15e-3)" "potential prognostic favorable (1.14e-4)" "unprognostic (1.84e-1)" "unprognostic (7.69e-2)" "unprognostic (3.58e-1)" "unprognostic (4.94e-2)" "unprognostic (1.36e-1)" "unprognostic (4.57e-2)" "unprognostic (2.28e-2)" "unprognostic (6.68e-2)" "unprognostic (6.22e-2)" "unprognostic (2.47e-1)" "unprognostic (2.90e-2)" "unprognostic (3.24e-2)" "unprognostic (5.91e-2)" "unprognostic (1.87e-1)" "unprognostic (5.13e-2)" "unprognostic (5.24e-2)" "unprognostic (2.23e-1)" "unprognostic (3.53e-1)" "unprognostic (9.85e-3)" SLC45A4 KIAA1126 ENSG00000022567 "Solute carrier family 45 member 4" Q5BKX6 8 141207166-141308305 "Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 393.8;Endometrial luminal cells: 368.9;Neutrophils: 831.4;Renal collecting duct principal cells: 371.1;Somatotrophs: 429.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "eosinophil: 8.3;neutrophil: 7.0" "Lineage enriched" "Detected in single" 22 "granulocytes: 8.3" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023154 Uncertain Approved "Plasma membrane" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 21: Testis - Mixed function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 40: Non-specific - Unknown function" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" "Plasma membrane" "HPA023154: " "unprognostic (9.53e-3)" "unprognostic (7.02e-3)" "unprognostic (5.34e-3)" "unprognostic (5.40e-2)" "unprognostic (8.89e-2)" "unprognostic (5.73e-3)" "unprognostic (1.24e-1)" "unprognostic (4.91e-3)" "unprognostic (2.36e-2)" "unprognostic (3.50e-2)" "validated prognostic favorable (2.33e-8)" "validated prognostic favorable (4.78e-4)" "unprognostic (1.65e-3)" "unprognostic (2.67e-1)" "unprognostic (2.08e-1)" "unprognostic (3.16e-2)" "unprognostic (7.61e-2)" "unprognostic (2.00e-2)" "unprognostic (2.62e-2)" "unprognostic (5.96e-2)" "unprognostic (4.65e-2)" "unprognostic (1.12e-1)" "unprognostic (1.65e-3)" "unprognostic (1.76e-1)" "unprognostic (2.70e-1)" "unprognostic (2.60e-1)" "unprognostic (1.35e-1)" "unprognostic (3.52e-2)" "unprognostic (6.85e-2)" "unprognostic (8.28e-3)" "unprognostic (1.49e-1)" SLC46A1 "HCP1, hPCFT, HsPCFT, MGC9564, PCFT" ENSG00000076351 "Solute carrier family 46 member 1" Q96NT5 17 28394642-28407197 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 88.2" "Cell type enhanced" "Detected in many" "Epicardial cells: 81.9;Hepatocytes: 37.2;Hofbauer cells: 45.7;Kupffer cells: 60.5;Late spermatids: 35.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB011614 Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 25: Non-specific - Transcription" "Cluster 34: Testis cancer - Unknown function" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 1 "Plasma membrane, Cytosol" "CAB011614: " "unprognostic (3.47e-1)" "unprognostic (1.64e-1)" "unprognostic (4.41e-2)" "unprognostic (3.51e-2)" "unprognostic (3.01e-1)" "unprognostic (1.51e-2)" "unprognostic (6.06e-2)" "unprognostic (1.42e-1)" "unprognostic (2.67e-1)" "unprognostic (6.88e-3)" "potential prognostic favorable (4.83e-6)" "unprognostic (1.14e-2)" "unprognostic (2.95e-3)" "unprognostic (8.49e-2)" "unprognostic (4.74e-2)" "unprognostic (3.07e-2)" "unprognostic (7.64e-2)" "unprognostic (2.99e-1)" "unprognostic (3.75e-1)" "unprognostic (2.31e-1)" "unprognostic (7.98e-2)" "unprognostic (3.33e-3)" "unprognostic (8.71e-2)" "unprognostic (5.48e-2)" "unprognostic (9.12e-2)" "unprognostic (1.22e-1)" "unprognostic (2.25e-1)" "unprognostic (4.16e-2)" "unprognostic (2.97e-1)" "unprognostic (9.89e-2)" "unprognostic (2.03e-1)" SLC46A2 "Ly110, TSCOT" ENSG00000119457 "Solute carrier family 46 member 2" Q9BY10 9 112878920-112890876 "Predicted membrane proteins, Transporters" "Immunity, Innate immunity, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 15.5;lung: 9.9;lymphoid tissue: 14.9;skin 1: 24.0" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 34.6;cDC: 10.6;Endometrial ciliated cells: 22.1;Epididymal principal cells: 22.7;Esophageal apical cells: 40.8;monocytes: 13.9;Prostatic club cells: 29.8;Prostatic hillock cells: 8.6;Urothelial cells: 15.6" "Cell type enhanced" "Detected in some" "upper rhombic lip: 3.6" "Cancer enriched" "Detected in single" 5 "Lung Adenocarcinoma (TCGA): 4.5" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "classical monocyte: 24.7;intermediate monocyte: 12.1" "Lineage enriched" "Detected in many" 5 "monocytes: 24.7" "Not detected" "Not detected" "Lung - Alveolar cells type 2, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA020098 Approved NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 58: Skin - Keratinization" "Cluster 15: Non-specific - Transcription" "Cluster 56: Non-specific - Sensory perception" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" "HPA020098: " "unprognostic (2.61e-3)" "unprognostic (1.89e-2)" "unprognostic (3.53e-2)" "unprognostic (9.26e-2)" SLC46A3 "DKFZp686A1775, FLJ42613" ENSG00000139508 "Solute carrier family 46 member 3" Q7Z3Q1 13 28700064-28718970 "Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 71.5;liver: 89.8" "Cell type enhanced" "Detected in many" "Breast lactating cells: 89.1;Enterocytes: 147.6;Kupffer cells: 81.0;Retinal bipolar cells: 71.0;Retinal pigment epithelial cells: 68.2;Sertoli cells: 86.3;Somatotrophs: 66.9;Thyrotrophs: 78.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039930 Approved Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 77: Intestine - Digestion" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 1: Enterocytes - Absorption and Digestion" 1 "Plasma membrane, Cytosol" "Actin filaments" "HPA039930: " "unprognostic (1.58e-1)" "unprognostic (7.85e-2)" "unprognostic (2.30e-1)" "unprognostic (3.67e-2)" "unprognostic (6.41e-2)" "unprognostic (1.71e-1)" "unprognostic (1.28e-1)" "unprognostic (9.93e-2)" "unprognostic (7.52e-2)" "unprognostic (4.30e-3)" "unprognostic (2.60e-3)" "unprognostic (1.63e-1)" "unprognostic (1.70e-3)" "unprognostic (1.75e-2)" "potential prognostic favorable (5.60e-6)" "unprognostic (1.95e-3)" "unprognostic (1.60e-1)" "unprognostic (4.16e-3)" "unprognostic (5.98e-2)" "unprognostic (1.27e-1)" "unprognostic (3.62e-3)" "unprognostic (3.41e-2)" "unprognostic (5.02e-3)" "unprognostic (1.52e-1)" "unprognostic (4.29e-2)" "unprognostic (2.90e-1)" "unprognostic (2.20e-1)" "unprognostic (1.18e-1)" "unprognostic (9.53e-2)" "unprognostic (2.64e-2)" "unprognostic (6.47e-2)" SLC47A1 "FLJ10847, MATE1" ENSG00000142494 "Solute carrier family 47 member 1" Q96FL8 17 19495385-19579034 "Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 124.8;kidney: 93.6;liver: 97.0" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 140.3;Early spermatids: 376.9;Epididymal efferent duct absorptive cells: 168.3;Late primary spermatocytes: 175.8;Myonuclei: 123.9;Myosatellite cells: 156.2;Proximal tubule cells: 453.8" "Cell type enhanced" "Detected in many" "fibroblast: 110.9;hippocampal dentate gyrus: 215.7" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 114.2;Kidney Renal Papillary Cell Carcinoma (TCGA): 101.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "eosinophil: 12.2;plasmacytoid DC: 6.6" "Group enriched" "Detected in many" 6 "dendritic cells: 6.6;granulocytes: 12.2" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Keratinocyte (other)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA021987 Enhanced NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 29: Forebrain - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 88: Proximal tubular cells - Transmembrane transport" 2 "HPA021987: " "unprognostic (1.43e-1)" "unprognostic (1.14e-2)" "unprognostic (1.92e-1)" "unprognostic (4.12e-3)" "unprognostic (7.23e-2)" "unprognostic (1.34e-1)" "unprognostic (7.34e-2)" "unprognostic (1.08e-1)" "unprognostic (8.69e-2)" "validated prognostic favorable (1.25e-9)" "validated prognostic favorable (8.12e-6)" "unprognostic (5.50e-3)" "unprognostic (5.83e-2)" "unprognostic (2.24e-1)" "potential prognostic favorable (1.83e-8)" "unprognostic (1.94e-2)" "unprognostic (1.62e-1)" "unprognostic (1.95e-1)" "unprognostic (3.80e-2)" "unprognostic (3.13e-2)" "unprognostic (1.29e-1)" "unprognostic (5.02e-2)" "unprognostic (6.93e-2)" "unprognostic (2.57e-2)" "unprognostic (1.75e-1)" "unprognostic (1.83e-1)" "unprognostic (6.93e-2)" "unprognostic (5.15e-3)" SLC47A2 "FLJ31196, MATE2, MATE2-K" ENSG00000180638 "Solute carrier family 47 member 2" Q86VL8 17 19678288-19718979 "Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "choroid plexus: 123.0;kidney: 61.3" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 157.9;Ependymal cells: 489.2;Epicardial cells: 113.7;Epididymal efferent duct ciliated cells: 142.3;Fallopian tube ciliated cells: 60.9;Proximal tubule cells: 298.8" "Cell type enriched" "Detected in many" 4 "ependymal cell: 536.5" "Group enriched" "Detected in many" 13 "Glioblastoma Multiforme (TCGA): 11.8;Kidney Renal Papillary Cell Carcinoma (TCGA): 42.5" "Region enhanced" "Detected in all" "choroid plexus: 79.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 3.9;Kidney cancer: 3.7" "Adipose visceral - Mesothelial cells, Breast - Breast myoepithelial cells, Kidney - Proximal tubular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in single" NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 3: Choroid plexus - Cilium" "Cluster 72: Neuronal - Signal transduction" "Cluster 34: Ciliated cells - Cilia assembly & function" "unprognostic (4.01e-2)" "unprognostic (8.36e-2)" "unprognostic (2.51e-3)" "unprognostic (4.36e-2)" "unprognostic (2.39e-1)" "unprognostic (5.03e-3)" "unprognostic (1.90e-1)" "unprognostic (2.35e-2)" "unprognostic (2.75e-1)" "unprognostic (4.50e-2)" "unprognostic (2.54e-1)" "unprognostic (9.33e-2)" SLC48A1 "FLJ20489, hHRG-1, HRG1" ENSG00000211584 "Solute carrier family 48 member 1" Q6P1K1 12 47753916-47782751 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 131.3" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 104.8;Oligodendrocytes: 142.3;Podocytes: 81.6" "Cell type enhanced" "Detected in all" "oligodendrocyte: 173.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065396, HPA073994" Approved Supported Vesicles NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 6 Vesicles "HPA065396: , HPA073994: " "unprognostic (8.99e-2)" "unprognostic (7.70e-2)" "unprognostic (9.05e-2)" "unprognostic (3.11e-1)" "unprognostic (3.34e-1)" "unprognostic (2.06e-2)" "unprognostic (8.10e-2)" "unprognostic (3.21e-1)" "unprognostic (4.14e-1)" "unprognostic (2.79e-3)" "potential prognostic favorable (2.31e-5)" "unprognostic (1.65e-3)" "unprognostic (4.11e-1)" "potential prognostic unfavorable (2.58e-6)" "unprognostic (1.72e-2)" "unprognostic (4.65e-1)" "unprognostic (1.66e-1)" "unprognostic (2.10e-1)" "unprognostic (5.42e-2)" "unprognostic (3.30e-2)" "unprognostic (9.62e-3)" "unprognostic (3.17e-2)" "unprognostic (2.85e-2)" "unprognostic (2.30e-2)" "unprognostic (6.16e-2)" "unprognostic (1.44e-1)" "unprognostic (4.03e-2)" "unprognostic (1.06e-1)" "unprognostic (2.42e-1)" "unprognostic (4.69e-1)" "unprognostic (4.15e-2)" SLC49A3 "FLJ22269, LP2561, MFSD7" ENSG00000169026 "Solute carrier family 49 member 3" Q6UXD7 4 681829-689271 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 39.6;Decidual stromal cells: 24.8;Early spermatids: 36.7;Esophageal apical cells: 32.1;Extravillous trophoblasts: 46.4;Kupffer cells: 24.6;Late primary spermatocytes: 52.9;Late spermatids: 55.6" "Cell type enhanced" "Detected in many" "endothelial cell: 7.3" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 30.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (granular), Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA043593 Uncertain NA NA "Cluster 47: Testis - Mixed function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 7: Liver cancer - Metabolism" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" "HPA043593: " "unprognostic (1.89e-1)" "unprognostic (2.31e-2)" "unprognostic (1.66e-1)" "unprognostic (1.16e-1)" "unprognostic (4.21e-2)" "unprognostic (4.78e-2)" "unprognostic (1.09e-2)" "unprognostic (9.05e-3)" "unprognostic (2.72e-1)" "unprognostic (2.09e-3)" "unprognostic (1.23e-1)" "unprognostic (2.64e-2)" "unprognostic (1.78e-1)" "unprognostic (2.63e-2)" "unprognostic (1.29e-1)" "unprognostic (2.00e-2)" "unprognostic (1.05e-1)" "unprognostic (1.17e-1)" "unprognostic (4.36e-2)" "unprognostic (7.85e-2)" "unprognostic (2.70e-1)" "unprognostic (2.30e-1)" "unprognostic (2.07e-2)" "unprognostic (5.69e-2)" "unprognostic (2.50e-1)" "unprognostic (1.50e-2)" "unprognostic (1.07e-2)" "unprognostic (1.05e-1)" "unprognostic (2.32e-1)" SLC49A4 "DIRC2, FLJ14784, RCC4" ENSG00000138463 "Solute carrier family 49 member 4" Q96SL1 3 122795069-122881139 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 255.1;Myonuclei: 327.3;Neutrophil progenitors: 258.0;Neutrophils: 1105.6;Syncytiotrophoblasts: 589.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Macrophages, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072579 Supported Vesicles NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 29: Neutrophils - Innate immune cellular maintenance" Vesicles "HPA072579: " "unprognostic (4.76e-2)" "unprognostic (4.49e-2)" "unprognostic (4.92e-2)" "unprognostic (1.51e-1)" "unprognostic (4.47e-2)" "unprognostic (2.49e-1)" "unprognostic (4.13e-3)" "unprognostic (1.07e-1)" "unprognostic (6.37e-2)" "potential prognostic favorable (8.26e-8)" "unprognostic (2.29e-2)" "unprognostic (5.05e-2)" "unprognostic (5.81e-3)" "unprognostic (2.87e-2)" "unprognostic (4.43e-2)" "unprognostic (1.08e-1)" "unprognostic (2.34e-1)" "unprognostic (1.05e-1)" "unprognostic (2.41e-2)" "potential prognostic unfavorable (1.57e-4)" "unprognostic (1.69e-1)" "unprognostic (3.00e-1)" "unprognostic (2.64e-2)" "unprognostic (3.82e-2)" "unprognostic (2.06e-1)" "unprognostic (1.02e-1)" "unprognostic (1.18e-1)" "unprognostic (2.79e-1)" "unprognostic (5.97e-2)" SLC4A1 "AE1, CD233, DI, EPB3, FR, RTA1A, SW, WD, WR" ENSG00000004939 "Solute carrier family 4 member 1 (Diego blood group)" P02730 17 44248390-44268141 "Blood group antigen proteins, CD markers, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Anion exchange, Ion transport, Transport" "Blood group antigen" "Disease variant, Elliptocytosis, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "bone marrow: 379.7" "Group enriched" "Detected in some" 38 "Erythrocyte progenitors: 364.9;Erythrocytes: 670.0;Renal collecting duct intercalated cells: 309.7" "Cell type enhanced" "Detected in single" "central nervous system macrophage: 1.8" "Cancer enriched" "Detected in many" 56 "Kidney Chromophobe (TCGA): 363.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 62 "Leukemia: 15.2" "Kidney - Intercalated cells, Liver - Erythroid cells, Pituitary gland - Neutrophils, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Spleen - Erythrocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA015584, CAB034438, HPA063911" Enhanced NA NA 41000000 "Cluster 15: Bone marrow - Innate immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 15 "CAB034438: , HPA015584: , HPA063911: " "unprognostic (1.32e-1)" "unprognostic (2.52e-1)" "unprognostic (2.13e-1)" "unprognostic (2.49e-2)" "unprognostic (1.46e-1)" "unprognostic (8.00e-2)" "unprognostic (2.46e-2)" "unprognostic (2.60e-3)" "unprognostic (1.76e-1)" "unprognostic (1.98e-2)" SLC4A10 "NBCn2, NCBE" ENSG00000144290 "Solute carrier family 4 member 10" Q6U841 2 161424332-161985282 "Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Symport, Transport" "Autism spectrum disorder, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 21 "brain: 32.6;choroid plexus: 54.0;retina: 31.8" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 536.6;Brain inhibitory neurons: 522.7;Choroid plexus epithelial cells: 2418.8;Oligodendrocyte progenitor cells: 218.6;Other brain neurons: 361.4;Retinal amacrine cells: 352.5;Retinal bipolar cells: 726.1;Retinal ganglion cells: 231.8" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 2639.3" "Cancer enhanced" "Detected in single" "Glioblastoma Multiforme (TCGA): 2.8" "Region enhanced" "Detected in all" "choroid plexus: 311.0" "Immune cell enriched" "Detected in some" 8 "MAIT T-cell: 63.4" "Lineage enriched" "Detected in single" 65 "T-cells: 63.4" "Cancer enhanced" "Detected in some" "prostate cancer: 1.8" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034755, HPA076725" Enhanced NA NA "Cluster 1: T-cells - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 2 "HPA034755: , HPA076725: " "unprognostic (2.19e-1)" "unprognostic (3.46e-3)" "unprognostic (4.45e-1)" SLC4A11 "BTR1, CDPD1, CHED2, dJ794I6.2, FECD4, NaBC1" ENSG00000088836 "Solute carrier family 4 member 11" Q8NBS3 20 3227417-3239559 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Anion exchange, Ion transport, Symport, Transport" "Corneal dystrophy, Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 19.3;kidney: 75.8;salivary gland: 68.1;thyroid gland: 74.6" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 40.8;Lacrimal acinar cells: 139.5;Loop of henle epithelial cells: 46.6;Papillary tip epithelial cells: 64.2;Renal collecting duct principal cells: 94.7;Respiratory deuterosomal cells: 36.3;Respiratory secretory cells: 34.2;Salivary basal cells: 39.9;Salivary duct cells: 98.2;Salivary ionocytes: 262.4;Submucosal glandular cells: 75.0" "Cell type enhanced" "Detected in some" "cerebellar inhibitory: 19.4;pericyte: 24.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary gland ductal cells, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA018120, HPA058377" Uncertain Uncertain Nucleoplasm,Vesicles NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" Nucleoplasm Vesicles "HPA018120: , HPA058377: " "unprognostic (4.33e-2)" "unprognostic (1.85e-1)" "unprognostic (1.53e-2)" "unprognostic (4.51e-2)" "unprognostic (1.30e-1)" "unprognostic (1.10e-1)" "unprognostic (4.93e-2)" "unprognostic (1.08e-2)" "unprognostic (2.73e-2)" "unprognostic (1.53e-1)" "unprognostic (3.08e-1)" "unprognostic (1.54e-1)" "unprognostic (8.13e-3)" "unprognostic (5.66e-3)" "unprognostic (1.48e-1)" "unprognostic (2.51e-2)" "unprognostic (1.00e-1)" "unprognostic (3.84e-2)" "unprognostic (2.46e-2)" "unprognostic (2.26e-2)" "unprognostic (2.05e-1)" "unprognostic (1.96e-1)" "unprognostic (3.41e-1)" "unprognostic (1.30e-1)" "unprognostic (1.24e-1)" "unprognostic (1.93e-1)" "unprognostic (2.84e-3)" "unprognostic (4.66e-3)" "unprognostic (5.14e-1)" "unprognostic (2.56e-1)" "unprognostic (7.70e-2)" SLC4A1AP "HLC3, kanadaptin" ENSG00000163798 "Solute carrier family 4 member 1 adaptor protein" Q9BWU0 2 27663426-27695366 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 147.9;Late primary spermatocytes: 102.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036679 Approved Supported "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 3: Early primary spermatocytes - Early meiosis" 36 Nucleoplasm "Vesicles, Plasma membrane" "HPA036679: " "unprognostic (2.23e-1)" "unprognostic (1.58e-2)" "unprognostic (8.45e-2)" "unprognostic (3.49e-1)" "unprognostic (2.93e-2)" "unprognostic (1.18e-1)" "unprognostic (5.42e-1)" "unprognostic (1.19e-3)" "unprognostic (2.00e-2)" "unprognostic (2.81e-2)" "potential prognostic favorable (6.84e-5)" "unprognostic (3.86e-2)" "unprognostic (1.86e-1)" "potential prognostic unfavorable (4.53e-9)" "unprognostic (4.90e-3)" "unprognostic (1.16e-2)" "unprognostic (5.79e-3)" "unprognostic (5.10e-3)" "unprognostic (4.24e-2)" "unprognostic (1.87e-1)" "unprognostic (2.47e-2)" "unprognostic (2.01e-1)" "potential prognostic unfavorable (1.72e-4)" "unprognostic (9.33e-2)" "unprognostic (1.74e-1)" "unprognostic (2.18e-1)" "unprognostic (1.39e-1)" "unprognostic (7.81e-2)" "unprognostic (1.60e-1)" "unprognostic (3.09e-1)" "unprognostic (3.05e-2)" SLC4A2 "AE2, BND3L, EPB3L1, HKB3, NBND3" ENSG00000164889 "Solute carrier family 4 member 2" P04920 7 151057210-151076526 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Anion exchange, Antiport, Ion transport, Transport" Osteopetrosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 264.8" "Group enriched" "Detected in many" 4 "Choroid plexus epithelial cells: 329.3;Parietal cells: 169.7;Retinal pigment epithelial cells: 332.5;Syncytiotrophoblasts: 127.0" "Cell type enriched" "Detected in many" 12 "choroid plexus epithelial cell: 368.4" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 13 "choroid plexus: 1044.1" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019339 Enhanced Uncertain "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" 8 "Nuclear speckles, Plasma membrane" Cytosol "HPA019339: " "unprognostic (8.69e-3)" "unprognostic (3.41e-1)" "unprognostic (4.51e-1)" "unprognostic (4.66e-3)" "unprognostic (1.59e-1)" "unprognostic (1.60e-1)" "unprognostic (1.30e-1)" "unprognostic (8.92e-2)" "unprognostic (2.02e-1)" "unprognostic (3.14e-2)" "potential prognostic favorable (1.09e-5)" "unprognostic (5.90e-2)" "unprognostic (6.67e-2)" "validated prognostic unfavorable (4.42e-5)" "validated prognostic unfavorable (8.83e-4)" "unprognostic (1.13e-2)" "unprognostic (1.54e-1)" "unprognostic (7.88e-2)" "unprognostic (1.99e-1)" "unprognostic (2.04e-1)" "unprognostic (6.88e-3)" "unprognostic (1.27e-1)" "unprognostic (3.11e-1)" "unprognostic (1.27e-1)" "unprognostic (1.71e-1)" "unprognostic (2.22e-1)" "unprognostic (2.42e-1)" "unprognostic (1.10e-1)" "unprognostic (2.15e-1)" "unprognostic (2.01e-1)" "unprognostic (2.12e-1)" SLC4A3 "AE3, SLC2C" ENSG00000114923 "Solute carrier family 4 member 3" P48751 2 219627394-219641980 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Anion exchange, Antiport, Ion transport, Transport" "Disease variant, Short QT syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 265.9;ovary: 122.8" "Group enriched" "Detected in many" 5 "Cardiomyocytes: 124.8;Retinal horizontal cells: 350.6" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 25.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 34 "myeloid DC: 1.4;plasmacytoid DC: 5.8" "Lineage enriched" "Detected in single" 53 "dendritic cells: 5.8" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Minor Salivary Gland - Minor salivary glandular cells, Skin - Outer root sheath cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063498 Approved Nucleoplasm NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 35: Non-specific - Mixed function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 69: Skin cancer - ECM organization" "Cluster 109: Neurons - Neuronal signaling" 1 Nucleoplasm "HPA063498: " "unprognostic (1.06e-2)" "unprognostic (9.83e-2)" "unprognostic (1.15e-1)" "unprognostic (1.30e-1)" "unprognostic (1.07e-1)" "unprognostic (2.06e-2)" "potential prognostic unfavorable (2.62e-4)" "unprognostic (4.12e-2)" "unprognostic (3.00e-1)" "potential prognostic unfavorable (1.56e-7)" "unprognostic (2.34e-3)" "unprognostic (1.99e-1)" "unprognostic (1.73e-1)" "unprognostic (1.01e-1)" "unprognostic (2.08e-1)" "unprognostic (1.21e-1)" "unprognostic (2.65e-1)" "unprognostic (5.56e-2)" "unprognostic (1.65e-1)" "unprognostic (1.13e-2)" "unprognostic (1.14e-3)" "unprognostic (7.57e-2)" "unprognostic (4.41e-2)" "unprognostic (3.24e-3)" "unprognostic (2.97e-3)" "unprognostic (1.41e-1)" "unprognostic (2.56e-1)" "unprognostic (6.52e-2)" "unprognostic (3.79e-2)" SLC4A4 "hhNMC, HNBC1, NBC1, NBC2, pNBC, SLC4A5" ENSG00000080493 "Solute carrier family 4 member 4" Q9Y6R1 4 71062667-71572087 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 111.6;pancreas: 245.3" "Cell type enhanced" "Detected in many" "Astrocytes: 1379.0;Bergmann glia: 4233.7;Colonocytes: 579.5;Pancreatic duct cells: 3794.9;Pituicytes/FSCs: 1072.2;Prostatic glandular cells: 666.1;Proximal tubule cells: 967.8;Retinal ganglion cells: 691.4" "Cell type enhanced" "Detected in all" "astrocyte: 1523.4;Bergmann glia: 4574.7" "Group enriched" "Detected in many" 5 "Glioblastoma Multiforme (TCGA): 40.3;Kidney Renal Clear Cell Carcinoma (TCGA): 36.9;Kidney Renal Papillary Cell Carcinoma (TCGA): 26.3;Pancreatic Adenocarcinoma (TCGA): 32.3;Prostate Adenocarcinoma (TCGA): 71.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 21.0;prostate cancer: 13.6" "Adipose visceral - Mesothelial cells, Kidney - Proximal tubular cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022493, HPA035628, HPA035629, HPA079220" Enhanced Approved "Plasma membrane,Cytosol" NA NA 4500 "Cluster 8: Pancreas - Proteolysis" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 28: Astrocytes - Homeostasis & neuron support" 4 "Plasma membrane" Cytosol "CAB022493: , HPA035628: , HPA035629: , HPA079220: " "unprognostic (2.46e-1)" "unprognostic (2.84e-2)" "unprognostic (3.41e-2)" "unprognostic (1.01e-1)" "potential prognostic favorable (9.95e-4)" "unprognostic (2.90e-1)" "unprognostic (1.97e-1)" "potential prognostic unfavorable (7.31e-4)" "unprognostic (3.54e-2)" "validated prognostic favorable (1.95e-8)" "validated prognostic favorable (2.79e-4)" "unprognostic (3.00e-1)" "unprognostic (7.36e-2)" "unprognostic (8.53e-3)" "unprognostic (7.54e-2)" "unprognostic (1.58e-1)" "unprognostic (1.54e-3)" "unprognostic (7.39e-2)" "unprognostic (5.57e-2)" "unprognostic (1.29e-1)" "unprognostic (1.16e-1)" "unprognostic (1.82e-1)" "unprognostic (8.54e-3)" "unprognostic (2.09e-1)" "unprognostic (1.19e-1)" "unprognostic (1.32e-3)" "unprognostic (6.62e-3)" SLC4A5 NBC4 ENSG00000188687 "Solute carrier family 4 member 5" Q9BY07 2 74216242-74343416 "Cancer-related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Anion exchange, Ion transport, Sodium transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "choroid plexus: 41.5;parathyroid gland: 11.5;retina: 38.8;testis: 14.8;thyroid gland: 25.0" "Cell type enriched" "Detected in some" 10 "Choroid plexus epithelial cells: 484.6" "Group enriched" "Detected in all" 4 "cerebellar inhibitory: 115.3;choroid plexus epithelial cell: 372.0" "Group enriched" "Detected in many" 6 "Kidney Chromophobe (TCGA): 21.4;Thyroid Carcinoma (TCGA): 30.2" "Region enriched" "Detected in all" 5 "choroid plexus: 161.3" "Immune cell enhanced" "Detected in some" "basophil: 4.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Group enriched" "Detected in many" 5 "basal ganglia: 1.6;hippocampal formation: 5.2;pons and medulla: 6.5;thalamus: 3.5" "Low region specificity" "Detected in all" HPA036621 Uncertain NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 101: Choroid plexus epithelial cells - Ion transport" "HPA036621: " "unprognostic (7.12e-2)" "unprognostic (4.09e-1)" "unprognostic (1.59e-2)" "unprognostic (1.42e-2)" "unprognostic (3.59e-2)" "unprognostic (1.21e-1)" "unprognostic (2.65e-1)" "unprognostic (1.11e-2)" "unprognostic (1.00e-1)" "unprognostic (1.36e-3)" "unprognostic (2.73e-1)" "unprognostic (2.72e-1)" "unprognostic (1.91e-1)" "potential prognostic favorable (2.71e-5)" "unprognostic (3.41e-2)" "unprognostic (2.43e-1)" "unprognostic (1.02e-2)" "unprognostic (2.85e-1)" "unprognostic (1.93e-2)" "unprognostic (3.81e-2)" "unprognostic (1.74e-1)" "unprognostic (3.17e-2)" "unprognostic (9.06e-2)" "unprognostic (1.78e-1)" "unprognostic (2.41e-2)" "unprognostic (2.12e-2)" "unprognostic (2.66e-1)" "unprognostic (1.57e-1)" SLC4A7 "NBC3, SBC2, SLC4A6" ENSG00000033867 "Solute carrier family 4 member 7" Q9Y6M7 3 27372721-27484420 "Essential proteins, Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 53.6;retina: 67.5" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 892.2;Loop of henle epithelial cells: 613.9;Microglia: 618.3;Rod photoreceptor cells: 995.3" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 787.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022494, HPA035857" Enhanced Supported "Plasma membrane,Focal adhesion sites,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 42: Retina - Visual perception" "Cluster 29: Forebrain - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 79: Photoreceptor cells - Phototransduction" 34 "Plasma membrane" "Focal adhesion sites, Cytosol" "CAB022494: , HPA035857: " "unprognostic (2.76e-2)" "unprognostic (7.34e-2)" "unprognostic (9.22e-2)" "unprognostic (1.21e-1)" "unprognostic (1.28e-1)" "unprognostic (4.18e-1)" "unprognostic (1.06e-1)" "unprognostic (1.00e-1)" "unprognostic (3.52e-1)" "unprognostic (2.13e-3)" "unprognostic (1.42e-1)" "unprognostic (1.18e-1)" "unprognostic (1.77e-1)" "potential prognostic unfavorable (8.41e-4)" "unprognostic (2.69e-1)" "unprognostic (2.38e-1)" "potential prognostic unfavorable (7.49e-5)" "unprognostic (4.00e-2)" "unprognostic (5.71e-2)" "unprognostic (4.45e-1)" "unprognostic (3.13e-2)" "unprognostic (1.28e-1)" "unprognostic (1.63e-1)" "unprognostic (3.91e-2)" "unprognostic (2.17e-2)" "unprognostic (6.67e-3)" "unprognostic (1.54e-1)" "unprognostic (5.10e-2)" "unprognostic (1.77e-1)" "unprognostic (1.18e-1)" "unprognostic (3.13e-1)" SLC4A8 NBC3 ENSG00000050438 "Solute carrier family 4 member 8" Q2Y0W8 12 51391317-51515763 "Metabolic proteins, Predicted membrane proteins, Transporters" "Anion exchange, Antiport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 12.0;pituitary gland: 16.9;retina: 10.3;testis: 11.0" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 219.4;Corticotrophs: 192.4;Gonadotrophs: 178.9;Lactotrophs: 359.5;Oligodendrocytes: 239.9;Retinal amacrine cells: 206.6;Retinal bipolar cells: 173.2;Retinal horizontal cells: 222.4;Somatotrophs: 395.6;Thyrotrophs: 399.7" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Breast Invasive Carcinoma (TCGA): 4.4;Glioblastoma Multiforme (TCGA): 7.6;Testicular Germ Cell Tumor (TCGA): 11.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "Neuroblastoma: 24.4" "Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Beta cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077895 Approved "Plasma membrane" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 1 "Plasma membrane" "HPA077895: " "unprognostic (1.89e-1)" "unprognostic (1.81e-2)" "unprognostic (2.20e-1)" "unprognostic (2.22e-1)" "unprognostic (1.10e-1)" "potential prognostic favorable (5.23e-4)" "unprognostic (3.80e-1)" "unprognostic (5.33e-2)" "unprognostic (4.12e-1)" "potential prognostic favorable (2.28e-4)" "unprognostic (4.50e-2)" "unprognostic (8.16e-2)" "unprognostic (1.67e-1)" "unprognostic (1.33e-1)" SLC4A9 AE4 ENSG00000113073 "Solute carrier family 4 member 9" Q96Q91 5 140360194-140375141 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Anion exchange, Antiport, Ion transport, Transport" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 52 "kidney: 36.8" "Cell type enriched" "Detected in some" 45 "Renal collecting duct intercalated cells: 744.3" "Cell type enhanced" "Detected in many" "mammillary body: 10.5" "Cancer enriched" "Detected in single" 18 "Kidney Chromophobe (TCGA): 10.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells, Kidney - Intercalated cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA051307 Uncertain Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" "Plasma membrane, Cytosol" Vesicles "HPA051307: " "unprognostic (1.11e-2)" SLC50A1 "HsSWEET1, RAG1AP1, RP11-540D14.5, RZPDo834D038D, SCP, slv, SWEET1" ENSG00000169241 "Solute carrier family 50 member 1" Q9BRV3 1 155135344-155138857 "Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 95.6" "Cell type enhanced" "Detected in many" "Breast lactating cells: 557.7;Epididymal principal cells: 157.9;Esophageal apical cells: 115.7;Extravillous trophoblasts: 173.2;Goblet cells: 166.4;Platelets: 136.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018095 Enhanced NA NA "Cluster 32: Basophils - Transcription" "Cluster 22: Epididymis - Mixed function" "Cluster 44: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 4: Breast lactating luminal cells - Lactation" 3 "HPA018095: " "unprognostic (2.50e-1)" "unprognostic (4.31e-2)" "unprognostic (4.52e-2)" "unprognostic (1.32e-1)" "unprognostic (8.08e-2)" "unprognostic (4.31e-2)" "unprognostic (1.61e-1)" "unprognostic (1.92e-2)" "unprognostic (1.14e-3)" "validated prognostic unfavorable (2.12e-5)" "validated prognostic unfavorable (9.68e-4)" "unprognostic (1.07e-2)" "unprognostic (2.58e-3)" "unprognostic (2.57e-2)" "unprognostic (2.74e-2)" "unprognostic (4.44e-1)" "unprognostic (2.51e-1)" "unprognostic (2.89e-2)" "unprognostic (7.03e-2)" "unprognostic (6.44e-2)" "unprognostic (1.30e-2)" "unprognostic (6.01e-2)" "unprognostic (4.94e-2)" "unprognostic (3.58e-2)" "potential prognostic unfavorable (2.48e-4)" "unprognostic (4.69e-2)" "unprognostic (2.35e-2)" "unprognostic (6.69e-2)" "unprognostic (1.45e-1)" "unprognostic (1.52e-1)" SLC51A OSTalpha ENSG00000163959 "Solute carrier family 51 subunit alpha" Q86UW1 3 196211487-196243178 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "intestine: 60.7;liver: 66.7" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 112.4;Colonocytes: 66.1;Enterocytes: 311.9;Epicardial cells: 88.7;Hepatocytes: 59.7;Neutrophil progenitors: 66.5;Neutrophils: 58.6;Peritubular myoid cells: 95.7" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 8 "Liver Hepatocellular Carcinoma (TCGA): 56.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Pituitary gland - Gonadotropes, Spleen - Neutrophils_2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA045488 Enhanced NA NA "Cluster 77: Intestine - Digestion" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 2 "HPA045488: " "unprognostic (1.92e-1)" "unprognostic (1.14e-1)" "unprognostic (5.62e-3)" "unprognostic (1.06e-1)" "unprognostic (4.75e-2)" "unprognostic (1.21e-2)" "validated prognostic favorable (1.60e-6)" "validated prognostic favorable (3.56e-4)" "unprognostic (1.79e-1)" "potential prognostic favorable (5.30e-4)" "unprognostic (5.93e-2)" "unprognostic (1.34e-2)" "unprognostic (2.38e-2)" "unprognostic (2.15e-2)" "unprognostic (1.32e-2)" "unprognostic (4.08e-1)" "unprognostic (4.62e-2)" "unprognostic (1.15e-1)" "unprognostic (5.10e-2)" "unprognostic (2.52e-2)" "unprognostic (8.04e-2)" "unprognostic (4.47e-2)" "unprognostic (2.43e-1)" SLC51B OSTbeta ENSG00000186198 "Solute carrier family 51 subunit beta" Q86UW2 15 65045387-65053397 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 39.4;intestine: 100.8" "Group enriched" "Detected in many" 4 "Colonocytes: 335.8;Enterocytes: 679.6;Epididymal efferent duct absorptive cells: 241.3" "Group enriched" "Detected in some" 4 "astrocyte: 6.1;ependymal cell: 6.3;pericyte: 4.3;vascular associated smooth muscle cell: 7.9" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 18.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 12.7" "Adipose subcutaneous - Smooth muscle cells, Colon - Colon enterocytes, Kidney - Proximal tubular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA008398, HPA008533" Enhanced Approved Vesicles,Mitochondria No NA "Cluster 77: Intestine - Digestion" "Cluster 46: Brainstem - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 4 Mitochondria Vesicles "HPA008398: , HPA008533: " "unprognostic (5.73e-2)" "unprognostic (5.07e-2)" "unprognostic (6.60e-2)" "unprognostic (1.55e-1)" "potential prognostic favorable (8.40e-7)" "unprognostic (1.34e-2)" "unprognostic (1.78e-1)" "unprognostic (2.29e-3)" "potential prognostic favorable (5.87e-4)" "unprognostic (2.11e-1)" "unprognostic (8.17e-3)" "unprognostic (3.66e-2)" "unprognostic (2.69e-1)" "unprognostic (5.06e-3)" "unprognostic (1.08e-1)" "unprognostic (8.15e-2)" "unprognostic (9.33e-2)" "unprognostic (8.15e-3)" SLC52A1 "FLJ10060, GPCR42, GPR172B, hRFT1, PAR2, RFVT1" ENSG00000132517 "Solute carrier family 52 member 1" Q9NWF4 17 5032600-5052009 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" Transport "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 17 "intestine: 33.6;placenta: 17.2;skin 1: 10.4" "Cell type enriched" "Detected in many" 4 "Syncytiotrophoblasts: 1054.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "cervical cancer: 5.3;Esophageal cancer: 5.0;head and neck cancer: 3.5" "Lung - Respiratory ciliated cells" NA NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 8 "unprognostic (6.12e-2)" "unprognostic (2.81e-2)" "unprognostic (8.69e-3)" "unprognostic (6.26e-2)" "unprognostic (1.93e-1)" "unprognostic (2.99e-2)" "potential prognostic favorable (1.33e-4)" "unprognostic (4.06e-2)" "unprognostic (1.78e-1)" "unprognostic (1.19e-2)" "unprognostic (4.52e-2)" "unprognostic (1.04e-1)" "unprognostic (4.09e-1)" "unprognostic (7.75e-2)" SLC52A2 "D15Ertd747e, FLJ11856, GPCR41, GPR172A, hRFT3, PAR1, RFVT2" ENSG00000185803 "Solute carrier family 52 member 2" Q9HAB3 8 144333957-144361286 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Host cell receptor for virus entry, Receptor" "Deafness, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 6.9;Bergmann glia: 6.2;Brain excitatory neurons: 13.2;Brain inhibitory neurons: 9.2;Microglia: 6.8;Oligodendrocyte progenitor cells: 8.0;Oligodendrocytes: 6.6;Other brain neurons: 14.6;Papillary tip epithelial cells: 9.1;Renal collecting duct principal cells: 7.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" HPA063036 Approved NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 40: Non-specific - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" 4 "HPA063036: " "unprognostic (1.20e-1)" "unprognostic (5.02e-3)" "unprognostic (1.81e-2)" "unprognostic (1.10e-1)" "unprognostic (2.58e-1)" "unprognostic (3.27e-3)" "unprognostic (3.74e-1)" "unprognostic (1.04e-2)" "unprognostic (8.66e-2)" "validated prognostic unfavorable (3.27e-6)" "validated prognostic unfavorable (2.06e-4)" "unprognostic (1.02e-2)" "potential prognostic unfavorable (3.01e-7)" "unprognostic (1.97e-2)" "unprognostic (5.70e-2)" "unprognostic (2.12e-1)" "unprognostic (2.02e-1)" "unprognostic (7.43e-3)" "unprognostic (1.76e-2)" "unprognostic (2.65e-3)" "unprognostic (3.96e-2)" "unprognostic (1.12e-1)" "unprognostic (1.27e-2)" "unprognostic (2.13e-1)" "unprognostic (2.21e-1)" "unprognostic (6.02e-2)" "unprognostic (1.85e-1)" "unprognostic (3.66e-1)" "unprognostic (2.16e-1)" SLC52A3 "bA371L19.1, C20orf54, hRFT2, RFVT3" ENSG00000101276 "Solute carrier family 52 member 3" Q9NQ40 20 760080-776015 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 18.1;testis: 46.8" "Cell type enhanced" "Detected in many" "Colonocytes: 30.3;Cytotrophoblasts: 48.5;Endometrial luminal cells: 41.2;Enterocytes: 141.7;Goblet cells: 23.5;Paneth cells: 23.2;Renal connecting tubule cells: 23.7;Sertoli cells: 42.5;Syncytiotrophoblasts: 80.2;Urothelial cells: 35.0" "Cell type enriched" "Detected in some" 35 "endothelial cell: 57.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.0" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "colorectal cancer: 20.8" "Kidney - Macrophages, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Skeletal muscle - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049391, HPA059078" Approved NA NA "Cluster 21: Testis - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 1: Enterocytes - Absorption and Digestion" 1 "HPA049391: , HPA059078: " "unprognostic (1.83e-2)" "unprognostic (2.90e-1)" "unprognostic (9.42e-3)" "unprognostic (1.26e-1)" "unprognostic (9.59e-2)" "unprognostic (7.21e-2)" "unprognostic (5.82e-2)" "unprognostic (7.79e-3)" "unprognostic (1.02e-1)" "unprognostic (1.42e-3)" "unprognostic (2.11e-2)" "potential prognostic unfavorable (4.35e-5)" "unprognostic (5.42e-3)" "unprognostic (2.48e-3)" "unprognostic (3.27e-1)" "unprognostic (8.40e-3)" "unprognostic (2.63e-2)" "unprognostic (2.07e-2)" "unprognostic (1.95e-1)" "potential prognostic unfavorable (5.25e-4)" "unprognostic (3.63e-2)" "unprognostic (6.15e-2)" "unprognostic (2.01e-1)" "unprognostic (5.09e-3)" "unprognostic (1.77e-2)" "potential prognostic favorable (2.59e-6)" "unprognostic (2.09e-1)" "unprognostic (1.85e-1)" "potential prognostic favorable (9.70e-5)" SLC5A1 "D22S675, NAGT, SGLT1" ENSG00000100170 "Solute carrier family 5 member 1" P13866 22 32043261-32113029 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Sugar transport, Symport, Transport" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "intestine: 497.5" "Cell type enriched" "Detected in many" 8 "Enterocytes: 1403.9" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in many" "Rectum Adenocarcinoma (TCGA): 30.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bile duct cancer: 3.3;colorectal cancer: 8.3;Gastric cancer: 2.7" "Colon - Colon enterocytes, Heart muscle - Cardiomyocytes, Kidney - Ascending Loop of Henle cells, Liver - Cholangiocytes, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in single" 26 "cerebellum: 7.6" "Low region specificity" "Detected in many" "CAB015467, HPA051805, HPA055106" Enhanced Approved "Nuclear membrane,Golgi apparatus,Plasma membrane" NA NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 9: Non-specific - Receptor signaling" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 1: Enterocytes - Absorption and Digestion" 1 "Golgi apparatus, Plasma membrane" "Nuclear membrane" "CAB015467: , HPA051805: , HPA055106: " "unprognostic (5.41e-2)" "unprognostic (1.39e-1)" "unprognostic (1.57e-1)" "unprognostic (7.52e-2)" "unprognostic (5.85e-2)" "unprognostic (5.91e-2)" "unprognostic (2.96e-1)" "validated prognostic favorable (4.06e-9)" "validated prognostic favorable (4.70e-4)" "potential prognostic favorable (1.39e-4)" "unprognostic (1.61e-2)" "unprognostic (6.50e-2)" "unprognostic (5.70e-3)" "unprognostic (3.20e-3)" "unprognostic (1.36e-1)" "unprognostic (1.53e-1)" "unprognostic (1.45e-1)" "unprognostic (5.68e-2)" "unprognostic (6.23e-2)" "unprognostic (1.15e-1)" "unprognostic (9.00e-3)" "unprognostic (1.10e-1)" "unprognostic (2.61e-3)" "unprognostic (2.22e-3)" SLC5A10 SGLT5 ENSG00000154025 "Solute carrier family 5 member 10" A0PJK1 17 18950345-19022595 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Sugar transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "kidney: 38.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 40.2;Epicardial cells: 213.8;Esophageal apical cells: 30.8;Esophageal suprabasal cells: 44.1;Late spermatids: 84.7;Melanocytes: 33.4;Proximal tubule cells: 171.9;Suprabasal keratinocytes: 40.4" "Cell type enhanced" "Detected in some" "leukocyte: 2.7" "Group enriched" "Detected in some" 8 "Kidney Renal Clear Cell Carcinoma (TCGA): 44.6;Kidney Renal Papillary Cell Carcinoma (TCGA): 20.5" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "intermediate monocyte: 1.8;non-classical monocyte: 4.9" "Lineage enriched" "Detected in single" 7 "monocytes: 4.9" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Spleen - B-cells (Spleen)" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA052014 Uncertain NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 72: Kidney - Transmembrane transport" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 88: Proximal tubular cells - Transmembrane transport" "HPA052014: " "unprognostic (2.36e-2)" "validated prognostic favorable (3.63e-7)" "validated prognostic favorable (2.93e-6)" "unprognostic (6.17e-2)" "unprognostic (1.56e-1)" "unprognostic (8.79e-2)" "unprognostic (2.07e-3)" SLC5A11 "KST1, SGLT6, SMIT2" ENSG00000158865 "Solute carrier family 5 member 11" Q8WWX8 16 24845841-24911628 "Metabolic proteins, Predicted membrane proteins, Transporters" "Apoptosis, Ion transport, Sodium transport, Sugar transport, Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "brain: 78.1" "Cell type enriched" "Detected in some" 9 "Oligodendrocytes: 715.5" "Cell type enriched" "Detected in all" 5 "oligodendrocyte: 1101.4" "Cancer enhanced" "Detected in single" "Glioblastoma Multiforme (TCGA): 1.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "liver cancer: 1.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA035331 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 50: Lymphoma - Unknown function" "Cluster 80: Oligodendrocytes - Myelination" 1 Nucleoplasm Cytosol "HPA035331: " "unprognostic (2.13e-1)" "unprognostic (1.90e-2)" "unprognostic (3.71e-1)" "unprognostic (1.32e-2)" SLC5A12 "MGC52019, SMCT2" ENSG00000148942 "Solute carrier family 5 member 12" Q1EHB4 11 26667020-26723427 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 45.1;intestine: 28.2;kidney: 160.2" "Cell type enhanced" "Detected in some" "Enterocytes: 377.7;Epididymal principal cells: 223.1;Proximal tubule cells: 1239.1" "Cell type enhanced" "Detected in some" "astrocyte: 6.4;committed oligodendrocyte precursor: 5.8" "Cancer enriched" "Detected in some" 5 "Kidney Renal Clear Cell Carcinoma (TCGA): 19.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "testis cancer: 3.0" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA060904 Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 9: Non-specific - Receptor signaling" "Cluster 56: Non-specific - Sensory perception" "Cluster 88: Proximal tubular cells - Transmembrane transport" "Plasma membrane" Nucleoplasm "HPA060904: " "unprognostic (6.79e-2)" "unprognostic (3.11e-2)" "validated prognostic favorable (1.88e-8)" "validated prognostic favorable (2.35e-4)" "unprognostic (5.04e-2)" "unprognostic (1.07e-2)" "unprognostic (2.39e-1)" SLC5A2 SGLT2 ENSG00000140675 "Solute carrier family 5 member 2" P31639 16 31483002-31490860 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Sugar transport, Symport, Transport" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "kidney: 52.2" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 33.4;Early spermatids: 53.3;Epicardial cells: 31.8;Late primary spermatocytes: 98.3;Late spermatids: 262.5;Proximal tubule cells: 140.3" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in some" "Kidney Renal Papillary Cell Carcinoma (TCGA): 2.6" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA041603 Enhanced NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 35: Non-specific - DNA binding" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 88: Proximal tubular cells - Transmembrane transport" 2 "HPA041603: " "unprognostic (5.46e-2)" "unprognostic (8.18e-3)" "unprognostic (3.07e-1)" "potential prognostic unfavorable (2.25e-4)" "unprognostic (8.87e-2)" "unprognostic (7.17e-2)" "unprognostic (1.40e-2)" "unprognostic (2.96e-1)" SLC5A3 "SMIT, SMIT1" ENSG00000198743 "Solute carrier family 5 member 3" P53794 21 34073578-34106260 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 27.1" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 4.8;Epididymal efferent duct absorptive cells: 4.4;Pituicytes/FSCs: 5.2" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 8.0;endothelial cell: 8.8" "Cancer enhanced" "Detected in all" "Thyroid Carcinoma (TCGA): 32.2" "Region enriched" "Detected in all" 4 "choroid plexus: 208.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029791 Supported "Plasma membrane" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 72: Kidney - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 13 "Plasma membrane" "HPA029791: " "unprognostic (6.74e-2)" "unprognostic (1.22e-1)" "unprognostic (2.00e-2)" "unprognostic (3.21e-2)" "unprognostic (3.68e-1)" "unprognostic (6.12e-2)" "unprognostic (2.07e-1)" "unprognostic (3.34e-1)" "unprognostic (3.87e-1)" "unprognostic (5.56e-2)" "unprognostic (1.92e-1)" "unprognostic (3.29e-2)" "unprognostic (1.04e-2)" "unprognostic (1.34e-2)" "unprognostic (2.40e-1)" "potential prognostic unfavorable (2.36e-4)" "unprognostic (1.55e-1)" "unprognostic (4.06e-2)" "unprognostic (2.20e-1)" "unprognostic (1.87e-1)" "potential prognostic unfavorable (1.26e-4)" "unprognostic (1.56e-2)" "unprognostic (1.49e-1)" "unprognostic (2.49e-3)" "unprognostic (9.88e-2)" "unprognostic (4.31e-2)" "unprognostic (1.58e-1)" "unprognostic (2.24e-1)" "unprognostic (2.07e-1)" "unprognostic (4.62e-1)" SLC5A4 "DJ90G24.4, SAAT1, SGLT3" ENSG00000100191 "Solute carrier family 5 member 4" Q9NY91 22 32218464-32255347 "Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "intestine: 18.6" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 6.4;Brain inhibitory neurons: 4.4;Enterocytes: 7.6;Erythrocyte progenitors: 10.9;Erythrocytes: 6.1;Lymphatic endothelial cells: 12.1;Melanocytes: 6.6;Other brain neurons: 4.1;Prostatic glandular cells: 10.0;Retinal bipolar cells: 5.7;Retinal ganglion cells: 7.7;Vascular endothelial cells: 15.7" "Cell type enhanced" "Detected in many" "endothelial cell: 28.7" "Cancer enriched" "Detected in some" 7 "Skin Cutaneous Melanoma (TCGA): 10.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 21 "skin cancer: 35.4" "Colon - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 24: Neurons - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 5 "unprognostic (5.27e-2)" "unprognostic (2.31e-1)" "unprognostic (4.53e-3)" "unprognostic (7.72e-3)" "unprognostic (6.39e-3)" SLC5A5 NIS ENSG00000105641 "Solute carrier family 5 member 5" Q92911 19 17871945-17895174 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Congenital hypothyroidism, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "choroid plexus: 134.2;salivary gland: 60.7;stomach 1: 55.5" "Group enriched" "Detected in some" 8 "Choroid plexus epithelial cells: 419.4;Conjunctival goblet cells: 551.5;Foveolar cells: 851.9" "Cell type enriched" "Detected in some" 12 "choroid plexus epithelial cell: 291.2" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 5.1;Thyroid Carcinoma (TCGA): 5.3" "Region enriched" "Detected in all" 15 "choroid plexus: 351.6" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in single" "Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB022364, HPA049055" Enhanced NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 68: Foveolar cells - Mucosal defense" 4 "CAB022364: , HPA049055: " "unprognostic (3.43e-1)" "unprognostic (9.56e-3)" "unprognostic (2.14e-2)" "unprognostic (2.00e-2)" "unprognostic (5.27e-2)" "unprognostic (1.59e-3)" "unprognostic (1.94e-1)" "unprognostic (2.46e-2)" "unprognostic (3.81e-2)" SLC5A6 SMVT ENSG00000138074 "Solute carrier family 5 member 6" Q9Y289 2 27199587-27212958 "Disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 96.2" "Cell type enhanced" "Detected in many" "Breast secretory cells: 78.2;Cardiomyocytes: 71.0;Cytotrophoblasts: 133.6;Epididymal principal cells: 104.5;Extravillous trophoblasts: 121.8;Migrating cytotrophoblasts: 172.5;Syncytiotrophoblasts: 302.3" "Group enriched" "Detected in all" 6 "choroid plexus epithelial cell: 40.1;endothelial cell: 102.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036958 Approved Approved "Plasma membrane" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 22: Epididymis - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 34: Testis cancer - Unknown function" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." 10 "Plasma membrane" "HPA036958: " "unprognostic (1.53e-2)" "unprognostic (1.07e-1)" "unprognostic (1.50e-1)" "unprognostic (1.17e-3)" "unprognostic (1.95e-1)" "unprognostic (7.16e-3)" "unprognostic (2.87e-1)" "unprognostic (1.35e-1)" "unprognostic (1.22e-1)" "unprognostic (8.12e-2)" "unprognostic (9.97e-3)" "potential prognostic unfavorable (6.30e-4)" "unprognostic (1.12e-2)" "unprognostic (1.59e-2)" "unprognostic (1.08e-1)" "unprognostic (6.43e-3)" "unprognostic (5.49e-3)" "unprognostic (1.77e-1)" "unprognostic (2.79e-2)" "unprognostic (2.27e-1)" "unprognostic (2.73e-2)" "unprognostic (1.33e-1)" "unprognostic (1.22e-1)" "unprognostic (7.91e-2)" "unprognostic (3.50e-2)" "unprognostic (1.17e-1)" "unprognostic (1.36e-1)" "unprognostic (1.95e-3)" "unprognostic (1.75e-2)" "unprognostic (3.92e-3)" "unprognostic (8.11e-2)" SLC5A7 "CHT1, hCHT" ENSG00000115665 "Solute carrier family 5 member 7" Q9GZV3 2 107986523-108013994 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Neurotransmitter biosynthesis, Sodium transport, Symport, Transport" "Congenital myasthenic syndrome, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.2;intestine: 2.6" "Cell type enhanced" "Detected in some" "Other brain neurons: 125.1;Prostatic hillock cells: 8.6;Respiratory basal cells: 12.3;Retinal amacrine cells: 64.9;Schwann cells: 29.4;Urothelial cells: 20.5" "Cell type enhanced" "Detected in some" "splatter: 14.6" "Cancer enhanced" "Detected in some" "Lung Squamous Cell Carcinoma (TCGA): 1.1;Testicular Germ Cell Tumor (TCGA): 1.5" "Region enhanced" "Detected in many" "pons: 72.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 11 "Neuroblastoma: 4.3" "Adrenal gland - Adrenal cortex cells, Colon - Enteric glia cells" "Group enriched" "Detected in many" 4 "basal ganglia: 23.1;hypothalamus: 9.0;midbrain: 9.4;pons and medulla: 14.4;thalamus: 6.2" "Group enriched" "Detected in many" 6 "basal ganglia: 28.3;pons: 36.6;spinal cord: 64.7" HPA046105 Approved "Nuclear bodies,Cell Junctions,Intermediate filaments" NA NA "Cluster 77: Intestine - Digestion" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 1 "Cell Junctions, Intermediate filaments" "Nuclear bodies" "HPA046105: " "unprognostic (6.56e-2)" "potential prognostic favorable (1.44e-4)" "unprognostic (2.68e-1)" SLC5A8 AIT ENSG00000256870 "Solute carrier family 5 member 8" Q8N695 12 101155493-101210238 "Metabolic proteins, Predicted membrane proteins, Transporters" "Apoptosis, Ion transport, Sodium transport, Symport, Transport" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "cervix: 19.0;kidney: 5.2;thyroid gland: 14.6" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 17.0;Brain inhibitory neurons: 22.8;Early spermatids: 7.2;Lacrimal acinar cells: 10.9;Loop of henle epithelial cells: 10.0;Neuroendocrine cells: 6.9;Other brain neurons: 11.2;Proximal tubule cells: 59.6;Renal connecting tubule cells: 22.5" "Cell type enhanced" "Detected in many" "mammillary body: 128.3;midbrain-derived inhibitory: 89.5" "Cancer enhanced" "Detected in some" "Kidney Renal Clear Cell Carcinoma (TCGA): 12.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "breast cancer: 1.4" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 33: Thyroid gland - Tissue development" "Cluster 1: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 88: Proximal tubular cells - Transmembrane transport" 2 "potential prognostic favorable (4.80e-4)" "unprognostic (2.26e-2)" "validated prognostic favorable (3.63e-8)" "validated prognostic favorable (1.32e-4)" "potential prognostic favorable (2.73e-4)" "unprognostic (4.54e-3)" "unprognostic (3.22e-2)" "unprognostic (2.01e-2)" "unprognostic (4.52e-2)" SLC5A9 SGLT4 ENSG00000117834 "Solute carrier family 5 member 9" Q2M3M2 1 48222685-48248644 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Sugar transport, Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "intestine: 40.9" "Cell type enhanced" "Detected in many" "Enterocytes: 96.1;Epicardial cells: 84.1;Epididymal efferent duct absorptive cells: 18.3;Fibro-adipogenic progenitors: 26.8;Late spermatids: 19.3;Proximal tubule cells: 45.5" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 11.0;oligodendrocyte precursor cell: 13.6" "Cancer enhanced" "Detected in some" "Kidney Renal Clear Cell Carcinoma (TCGA): 6.8;Liver Hepatocellular Carcinoma (TCGA): 5.4" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "liver cancer: 3.1" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Outer root sheath cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA050263 Approved "Actin filaments,Cytosol" NA NA "Cluster 77: Intestine - Digestion" "Cluster 6: Non-specific - Immune response" "Cluster 18: Liver cancer - Metabolism" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 1 "Actin filaments" Cytosol "HPA050263: " "potential prognostic favorable (7.58e-4)" "unprognostic (8.10e-2)" "unprognostic (2.20e-2)" "unprognostic (1.03e-2)" "unprognostic (4.32e-2)" "unprognostic (5.93e-2)" "unprognostic (1.69e-1)" "unprognostic (1.84e-1)" "unprognostic (2.22e-2)" "unprognostic (1.46e-2)" "unprognostic (3.88e-1)" SLC66A1 "FLJ20320, LAAT-1, LAAT1, PQLC2" ENSG00000040487 "Solute carrier family 66 member 1" Q6ZP29 1 19312326-19329300 "Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 31.4;Hofbauer cells: 60.5;Syncytiotrophoblasts: 83.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Hair cortex cells, Skin - Inner root sheath cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057810 Approved Supported Vesicles NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" Vesicles "HPA057810: " "unprognostic (3.23e-2)" "unprognostic (2.66e-1)" "unprognostic (6.53e-2)" "unprognostic (3.36e-2)" "unprognostic (1.70e-1)" "unprognostic (2.97e-2)" "unprognostic (9.20e-2)" "unprognostic (2.29e-1)" "unprognostic (3.15e-2)" "unprognostic (8.30e-3)" "unprognostic (1.81e-1)" "unprognostic (8.42e-2)" "potential prognostic unfavorable (2.43e-8)" "unprognostic (1.93e-1)" "unprognostic (3.16e-1)" "unprognostic (2.25e-1)" "unprognostic (4.23e-2)" "unprognostic (2.49e-1)" "unprognostic (2.01e-1)" "unprognostic (1.27e-2)" "unprognostic (3.26e-1)" "unprognostic (3.67e-1)" "unprognostic (2.81e-3)" "unprognostic (1.05e-3)" "unprognostic (3.42e-2)" "unprognostic (1.48e-1)" "unprognostic (1.55e-1)" "unprognostic (2.34e-1)" "unprognostic (9.45e-2)" SLC66A2 "FLJ22378, PQLC1" ENSG00000122490 "Solute carrier family 66 member 2" Q8N2U9 18 79902420-79951657 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 179.0" "Cell type enhanced" "Detected in many" "Hepatocytes: 247.8;Late spermatids: 302.9;Neutrophils: 293.2;Proximal tubule cells: 224.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Pituitary gland - Endothelial cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051666 Uncertain Approved Nucleoplasm NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 19 Nucleoplasm "HPA051666: " "unprognostic (3.35e-1)" "unprognostic (2.84e-1)" "unprognostic (2.69e-1)" "unprognostic (7.55e-2)" "unprognostic (2.99e-2)" "unprognostic (1.59e-3)" "potential prognostic favorable (7.89e-4)" "unprognostic (6.77e-2)" "unprognostic (9.99e-2)" "potential prognostic favorable (5.99e-5)" "unprognostic (1.10e-2)" "unprognostic (8.81e-3)" "unprognostic (1.82e-1)" "unprognostic (2.49e-1)" "unprognostic (5.76e-2)" "unprognostic (7.30e-2)" "unprognostic (1.67e-1)" "unprognostic (5.57e-3)" "unprognostic (1.15e-1)" "unprognostic (1.46e-1)" "unprognostic (3.70e-2)" "unprognostic (1.13e-1)" "unprognostic (1.07e-1)" "unprognostic (3.13e-1)" "unprognostic (7.66e-2)" "unprognostic (2.44e-1)" "unprognostic (2.26e-1)" "unprognostic (4.72e-2)" "unprognostic (1.71e-1)" SLC66A3 "C2orf22, MGC33602, PQLC3" ENSG00000162976 "Solute carrier family 66 member 3" Q8N755 2 11155198-11178870 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 116.6;Kupffer cells: 129.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 144.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA061607 Approved Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 22: Epididymis - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 27: Breast cancer - Unknown function" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" Cytosol "HPA061607: " "potential prognostic favorable (8.80e-4)" "unprognostic (1.34e-1)" "unprognostic (1.13e-1)" "unprognostic (7.63e-2)" "unprognostic (1.07e-1)" "unprognostic (2.00e-3)" "unprognostic (1.12e-3)" "unprognostic (8.82e-2)" "unprognostic (3.07e-1)" "potential prognostic favorable (5.99e-8)" "unprognostic (2.11e-1)" "potential prognostic unfavorable (9.33e-4)" "potential prognostic unfavorable (4.72e-4)" "unprognostic (4.28e-1)" "unprognostic (1.75e-1)" "unprognostic (5.01e-2)" "unprognostic (1.14e-1)" "unprognostic (8.88e-2)" "unprognostic (1.01e-2)" "unprognostic (2.57e-3)" "unprognostic (2.56e-1)" "unprognostic (4.00e-1)" "unprognostic (1.48e-2)" "unprognostic (2.15e-1)" "unprognostic (1.94e-1)" "unprognostic (1.12e-1)" "unprognostic (2.59e-1)" "unprognostic (1.49e-1)" "unprognostic (1.95e-2)" SLC6A1 "GABATHG, GABATR, GAT-1, GAT1, hGAT-1" ENSG00000157103 "Solute carrier family 6 member 1" P30531 3 10992186-11039247 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 85.6;liver: 82.4;retina: 34.6" "Cell type enhanced" "Detected in some" "Astrocytes: 287.7;Bergmann glia: 212.0;Brain inhibitory neurons: 242.9;Medullary thymic epithelial cells: 372.0;Müller glia: 75.0;Oligodendrocyte progenitor cells: 222.3;Oligodendrocytes: 150.3;Pericytes: 128.9;Retinal amacrine cells: 325.0" "Cell type enhanced" "Detected in all" "pericyte: 2290.5" "Group enriched" "Detected in some" 10 "Glioblastoma Multiforme (TCGA): 24.4;Liver Hepatocellular Carcinoma (TCGA): 25.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes, Pituitary gland - Fibroblasts, Testis - Peritubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013341, CAB022293" Enhanced NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 56: Non-specific - Sensory perception" "Cluster 22: Non-specific - Basic cellular functions" 8 "CAB022293: , HPA013341: " "unprognostic (3.31e-1)" "unprognostic (2.35e-1)" "unprognostic (3.24e-1)" "unprognostic (2.01e-1)" "unprognostic (8.90e-2)" "unprognostic (1.55e-1)" "unprognostic (4.36e-3)" "unprognostic (1.44e-3)" "unprognostic (2.06e-3)" "unprognostic (7.16e-2)" "unprognostic (2.08e-1)" "unprognostic (1.27e-1)" "unprognostic (2.71e-1)" SLC6A11 GAT3 ENSG00000132164 "Solute carrier family 6 member 11" P48066 3 10816201-10940714 "Metabolic proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "brain: 77.7" "Cell type enhanced" "Detected in some" "Astrocytes: 300.3;Brain inhibitory neurons: 53.2;Ependymal cells: 37.7;Esophageal suprabasal cells: 34.8;Extravillous trophoblasts: 43.8;Leydig cells: 33.5;Müller glia: 53.3;Oligodendrocyte progenitor cells: 30.9;Peritubular myoid cells: 43.5;Retinal amacrine cells: 121.1" "Group enriched" "Detected in all" 6 "astrocyte: 449.0;midbrain-derived inhibitory: 299.0" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 18.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 7.2" "Prostate - Prostate glandular cells, Skin - Keratinocyte (other), Testis - Peritubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037981 Supported Supported Uncertain Nucleoplasm,Vesicles NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 28: Astrocytes - Homeostasis & neuron support" Nucleoplasm Vesicles "HPA037981: " "unprognostic (3.04e-1)" "unprognostic (2.55e-1)" "unprognostic (3.55e-1)" "unprognostic (3.93e-2)" "unprognostic (1.19e-1)" "unprognostic (4.38e-2)" "unprognostic (1.00e-1)" "unprognostic (2.16e-2)" "unprognostic (8.58e-2)" "unprognostic (4.57e-2)" "unprognostic (1.13e-1)" "unprognostic (9.24e-2)" "unprognostic (1.60e-1)" "unprognostic (1.48e-2)" "unprognostic (3.63e-2)" "unprognostic (3.83e-2)" SLC6A12 BGT-1 ENSG00000111181 "Solute carrier family 6 member 12" P48065 12 190077-214570 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "kidney: 19.7;liver: 68.3" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 22.2;Endometrial luminal cells: 18.7;Hepatocytes: 38.8;Loop of henle epithelial cells: 63.2;Papillary tip epithelial cells: 19.1;Pericytes: 44.3;Proximal tubule cells: 90.7;Renal collecting duct intercalated cells: 19.7;Renal collecting duct principal cells: 43.7;Retinal pigment epithelial cells: 76.7" "Cell type enriched" "Detected in many" 6 "pericyte: 1055.4" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 25.5;Kidney Renal Papillary Cell Carcinoma (TCGA): 28.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 43 "classical monocyte: 4.9;intermediate monocyte: 4.8;myeloid DC: 2.1;neutrophil: 2.6;non-classical monocyte: 7.0" "Group enriched" "Detected in many" 40 "dendritic cells: 2.1;granulocytes: 2.6;monocytes: 7.0" "Group enriched" "Detected in some" 5 "liver cancer: 1.9;ovarian cancer: 4.2;testis cancer: 2.5;thyroid cancer: 2.3;Uterine cancer: 4.3" "Adipose subcutaneous - Macrophages, Liver - Hepatocytes, Minor Salivary Gland - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA034973 Approved Approved Vesicles NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 47: Endothelial cells - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 22: Non-specific - Basic cellular functions" 3 Vesicles "HPA034973: " "unprognostic (5.20e-2)" "unprognostic (3.83e-2)" "unprognostic (1.70e-1)" "unprognostic (7.24e-2)" "unprognostic (1.15e-1)" "unprognostic (8.87e-3)" "potential prognostic favorable (5.55e-5)" "unprognostic (2.34e-2)" "unprognostic (1.95e-2)" "unprognostic (5.25e-2)" "unprognostic (7.29e-2)" "unprognostic (8.46e-2)" "unprognostic (1.90e-1)" "unprognostic (3.89e-2)" "unprognostic (2.27e-2)" "unprognostic (3.88e-2)" "unprognostic (3.79e-2)" "unprognostic (2.74e-1)" "unprognostic (2.20e-1)" "unprognostic (1.84e-1)" "unprognostic (1.75e-3)" SLC6A13 GAT2 ENSG00000010379 "Solute carrier family 6 member 13" Q9NSD5 12 220621-262873 "Metabolic proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "kidney: 142.8;liver: 36.8" "Group enriched" "Detected in some" 14 "Proximal tubule cells: 421.7;Retinal pigment epithelial cells: 733.2" "Group enriched" "Detected in many" 31 "fibroblast: 408.5;pericyte: 665.0" "Group enriched" "Detected in many" 16 "Kidney Renal Clear Cell Carcinoma (TCGA): 135.1;Kidney Renal Papillary Cell Carcinoma (TCGA): 88.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 2.3" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Pituitary gland - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036449, HPA052726" Supported Nucleoplasm,Nucleoli,Mitochondria,Cytosol NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 38: Sub-cortical - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 88: Proximal tubular cells - Transmembrane transport" Mitochondria "Nucleoplasm, Nucleoli, Cytosol" "HPA036449: , HPA052726: " "unprognostic (3.49e-1)" "unprognostic (2.37e-1)" "unprognostic (1.29e-2)" "validated prognostic favorable (4.65e-8)" "validated prognostic favorable (3.80e-4)" "potential prognostic favorable (6.58e-5)" "unprognostic (3.89e-2)" "unprognostic (2.53e-3)" "unprognostic (1.60e-1)" "unprognostic (1.82e-1)" "unprognostic (2.85e-1)" "unprognostic (2.52e-2)" "unprognostic (3.24e-3)" SLC6A14 ENSG00000268104 "Solute carrier family 6 member 14" Q9UN76 X 116436606-116461458 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" Obesity "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 15.1;salivary gland: 20.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 470.2;Breast secretory cells: 74.6;Conjunctival goblet cells: 91.3;Endometrial secretory cells: 72.0;Lacrimal acinar cells: 74.3;Respiratory basal cells: 114.9;Respiratory deuterosomal cells: 136.8;Respiratory secretory cells: 228.2;Salivary acinar cells: 320.3;Salivary myoepithelial cells: 68.2;Transitional alveolar cells: 159.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 28.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "pancreatic cancer: 10.1" "Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells" HPA003193 Uncertain Approved "Vesicles,Plasma membrane,Primary cilium,Primary cilium tip,Mitochondria" NA NA "Cluster 82: Salivary gland - Secretion" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 81: Alveolar cells - Lung function" "Vesicles, Primary cilium, Primary cilium tip" "Plasma membrane, Mitochondria" "HPA003193: " "unprognostic (1.03e-1)" "unprognostic (6.33e-2)" "unprognostic (1.97e-1)" "unprognostic (1.30e-2)" "unprognostic (1.66e-1)" "unprognostic (1.29e-1)" "unprognostic (1.66e-2)" "unprognostic (3.02e-2)" "unprognostic (1.12e-3)" "unprognostic (2.32e-1)" "unprognostic (3.57e-3)" "unprognostic (2.20e-1)" "potential prognostic unfavorable (8.47e-4)" "unprognostic (5.67e-2)" "unprognostic (4.59e-1)" "unprognostic (1.21e-1)" "unprognostic (2.93e-1)" "unprognostic (1.89e-2)" "unprognostic (2.12e-1)" "unprognostic (4.89e-2)" SLC6A15 "FLJ10316, hv7-3, NTT73, SBAT1, V7-3" ENSG00000072041 "Solute carrier family 6 member 15" Q9H2J7 12 84859491-84913629 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Ion transport, Neurotransmitter transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 13.0;retina: 14.6" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 73.6;Brain inhibitory neurons: 59.5;Lactotrophs: 163.9;Melanocytes: 182.7;Oligodendrocytes: 64.1;Other brain neurons: 84.5;Retinal amacrine cells: 42.2;Retinal bipolar cells: 46.7;Retinal ganglion cells: 65.7;Retinal pigment epithelial cells: 89.5;Rod photoreceptor cells: 32.9;Somatotrophs: 95.4" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Head and Neck Squamous Cell Carcinoma (TCGA): 7.3;Lung Squamous Cell Carcinoma (TCGA): 6.5;Skin Cutaneous Melanoma (TCGA): 23.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 38.9;skin cancer: 33.3" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pituitary gland - Lactotropes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008609 Uncertain Approved Nucleoli,Vesicles NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 45 Nucleoli Vesicles "HPA008609: " "unprognostic (1.48e-2)" "unprognostic (1.21e-2)" "unprognostic (1.80e-2)" "unprognostic (2.33e-2)" "unprognostic (8.88e-2)" "unprognostic (1.72e-1)" "unprognostic (1.80e-2)" "potential prognostic unfavorable (3.10e-4)" "unprognostic (1.06e-1)" "unprognostic (2.88e-1)" "unprognostic (3.85e-2)" "unprognostic (2.18e-2)" "unprognostic (2.01e-1)" "unprognostic (8.71e-3)" SLC6A16 NTT5 ENSG00000063127 "Solute carrier family 6 member 16" Q9GZN6 19 49289638-49325215 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "testis: 88.0" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 126.8;Distal convoluted tubule cells: 63.1;Early primary spermatocytes: 179.7;Early spermatids: 101.8;Ependymal cells: 127.7;Late primary spermatocytes: 252.0;Respiratory ciliated cells: 71.5" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 121.9;ependymal cell: 139.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Rhabdoid: 19.1" "Adipose subcutaneous - Smooth muscle cells, Spleen - B-cells (Spleen), Testis - Early spermatids" "Not detected" "Not detected" HPA076812 Approved "Golgi apparatus" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 47: Testis - Mixed function" "Cluster 44: Non-specific - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 34: Ciliated cells - Cilia assembly & function" "Golgi apparatus" "HPA076812: " "unprognostic (2.18e-1)" "unprognostic (1.50e-1)" "unprognostic (2.13e-1)" "unprognostic (1.05e-3)" "unprognostic (1.40e-1)" "unprognostic (1.90e-1)" "unprognostic (2.01e-1)" "unprognostic (3.01e-2)" "unprognostic (4.47e-1)" "potential prognostic unfavorable (7.78e-6)" "unprognostic (2.54e-2)" "unprognostic (1.52e-3)" "unprognostic (4.71e-2)" "unprognostic (1.06e-2)" "unprognostic (1.53e-1)" "unprognostic (1.07e-1)" "unprognostic (1.59e-1)" "unprognostic (3.35e-2)" "unprognostic (9.08e-2)" "unprognostic (1.00e-2)" "unprognostic (1.11e-1)" "unprognostic (4.58e-1)" "potential prognostic unfavorable (7.05e-4)" "unprognostic (1.40e-1)" "unprognostic (3.11e-1)" "unprognostic (2.74e-1)" SLC6A17 NTT4 ENSG00000197106 "Solute carrier family 6 member 17" Q9H1V8 1 110150494-110202202 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Ion transport, Neurotransmitter transport, Sodium transport, Symport, Transport" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 53.7;pituitary gland: 23.8" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 42.5;Brain excitatory neurons: 55.9;Brain inhibitory neurons: 58.5;Corticotrophs: 75.0;Gonadotrophs: 51.1;Lactotrophs: 209.4;Melanocytes: 71.6;Other brain neurons: 39.1;Pancreatic islet cells: 35.6;Retinal amacrine cells: 36.0;Retinal ganglion cells: 27.0;Somatotrophs: 153.7;Thyrotrophs: 37.8" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in some" 7 "Skin Cutaneous Melanoma (TCGA): 27.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 6.9" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Beta cells, Pituitary gland - Lactotropes, Skin - Melanocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008043, HPA008044" Enhanced Approved Mitochondria NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 1 Mitochondria "HPA008043: , HPA008044: " "unprognostic (4.63e-2)" "unprognostic (2.66e-1)" "unprognostic (4.11e-2)" "potential prognostic favorable (9.08e-6)" "unprognostic (1.27e-2)" "unprognostic (4.28e-2)" "unprognostic (9.84e-3)" "unprognostic (6.10e-2)" "unprognostic (2.64e-1)" SLC6A18 "FLJ31236, Xtrp2" ENSG00000164363 "Solute carrier family 6 member 18" Q96N87 5 1225381-1246189 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Neurotransmitter transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 73 "kidney: 7.7" "Group enriched" "Detected in some" 4 "Enterocytes: 6.3;Paneth cells: 3.9;Proximal tubule cells: 8.9;Retinal bipolar cells: 5.5" "Not detected" "Not detected" "Group enriched" "Detected in some" 38 "Kidney Renal Clear Cell Carcinoma (TCGA): 8.7;Kidney Renal Papillary Cell Carcinoma (TCGA): 3.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA011885 Enhanced NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "HPA011885: " "validated prognostic favorable (7.46e-6)" "validated prognostic favorable (1.21e-4)" "unprognostic (4.04e-2)" SLC6A19 B0AT1 ENSG00000174358 "Solute carrier family 6 member 19" Q695T7 5 1201595-1225111 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 35 "intestine: 134.2;kidney: 82.9" "Cell type enriched" "Detected in some" 8 "Enterocytes: 677.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Kidney Renal Clear Cell Carcinoma (TCGA): 15.9;Kidney Renal Papillary Cell Carcinoma (TCGA): 7.3;Stomach Adenocarcinoma (TCGA): 7.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Leukemia: 6.1;liver cancer: 7.2" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Prostate - Prostate glandular cells, Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" "HPA037415, HPA043207" Enhanced NA NA "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 47: Leukemia - Hemostasis" "Cluster 1: Enterocytes - Absorption and Digestion" 3 "HPA037415: , HPA043207: " "unprognostic (1.70e-1)" "validated prognostic favorable (5.90e-9)" "validated prognostic favorable (2.51e-7)" "unprognostic (8.56e-3)" "unprognostic (5.60e-1)" "unprognostic (5.01e-2)" "unprognostic (4.64e-2)" "unprognostic (1.63e-1)" "unprognostic (5.26e-2)" "unprognostic (7.20e-2)" SLC6A2 "NAT1, NET, NET1, SLC6A5" ENSG00000103546 "Solute carrier family 6 member 2" P23975 16 55655988-55707645 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 9.9;placenta: 6.4;skin 1: 4.4;testis: 4.2" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 31.9;Epididymal efferent duct absorptive cells: 50.6;Epididymal efferent duct ciliated cells: 7.1;Extravillous trophoblasts: 19.9;Late primary spermatocytes: 16.2;Late spermatids: 9.0;Podocytes: 8.5;Syncytiotrophoblasts: 9.8" "Cell type enriched" "Detected in single" 4 "CGE interneuron: 3.5" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 6.2" "Region enriched" "Detected in some" 35 "pons: 192.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 50 "Neuroblastoma: 54.0" "Adrenal gland - Adrenal medulla cells, Minor Salivary Gland - Fibroblasts, Testis - Early spermatids" "Region enriched" "Detected in some" 4 "pons and medulla: 7.8" "Region enriched" "Detected in single" 19 "pons: 17.9" "HPA004057, HPA076311, CAB078195" Enhanced Supported Approved Mitochondria,Cytosol NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 2 Cytosol Mitochondria "CAB078195: , HPA004057: , HPA076311: " "unprognostic (6.90e-2)" "unprognostic (9.28e-2)" "unprognostic (3.02e-1)" "unprognostic (4.14e-2)" "unprognostic (1.29e-1)" "unprognostic (1.21e-1)" "unprognostic (1.57e-1)" "unprognostic (1.36e-2)" "unprognostic (1.63e-2)" SLC6A20 "IMINO, SIT1, XT3, Xtrp3" ENSG00000163817 "Solute carrier family 6 member 20" Q9NP91 3 45755449-45796574 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "choroid plexus: 47.2;intestine: 23.8" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 87.2;Conjunctival goblet cells: 52.4;Endometrial secretory cells: 61.6;Enterocytes: 116.7;Epididymal efferent duct absorptive cells: 41.0;Foveolar cells: 59.7;Pancreatic duct cells: 53.7;Retinal pigment epithelial cells: 392.2" "Group enriched" "Detected in some" 38 "choroid plexus epithelial cell: 65.9;fibroblast: 253.3" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 16.5" "Region enriched" "Detected in all" 12 "choroid plexus: 114.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bile duct cancer: 4.1;colorectal cancer: 12.9;Gastric cancer: 10.7;pancreatic cancer: 6.8" "Kidney - Macrophages, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" 12 "unprognostic (2.21e-2)" "unprognostic (2.54e-2)" "unprognostic (5.49e-3)" "unprognostic (8.82e-2)" "unprognostic (2.90e-2)" "unprognostic (4.81e-2)" "unprognostic (1.33e-1)" "unprognostic (4.45e-2)" "potential prognostic favorable (7.90e-9)" "unprognostic (1.34e-2)" "unprognostic (1.58e-1)" "unprognostic (1.87e-1)" "unprognostic (1.96e-1)" "unprognostic (1.40e-3)" "unprognostic (2.51e-1)" "unprognostic (1.58e-2)" "unprognostic (3.11e-2)" "unprognostic (5.61e-2)" "unprognostic (1.47e-1)" "unprognostic (2.96e-1)" "unprognostic (1.38e-1)" "unprognostic (7.79e-2)" SLC6A3 "DAT, DAT1" ENSG00000142319 "Solute carrier family 6 member 3" Q01959 5 1392794-1445440 "Disease related genes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Disease variant, Dystonia, FDA approved drug targets, Neurodegeneration, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 119 "brain: 92.9" "Cell type enriched" "Detected in some" 7 "Other brain neurons: 8.1" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 16 "Kidney Renal Clear Cell Carcinoma (TCGA): 6.9" "Region enriched" "Detected in some" 28 "midbrain: 133.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "Kidney cancer: 5.0" "Adipose visceral - Mesothelial cells" "Group enriched" "Detected in many" 8 "midbrain: 80.6;thalamus: 29.0" "Region enriched" "Detected in some" 152 "midbrain: 393.2" "HPA012763, HPA013602, CAB016249, CAB078172" Enhanced Supported Approved Vesicles NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 109: Neurons - Neuronal signaling" 14 Vesicles "CAB016249: , CAB078172: , HPA012763: , HPA013602: " "potential prognostic favorable (8.63e-6)" "unprognostic (2.08e-3)" SLC6A4 "5-HTT, HTT, OCD1, SERT1" ENSG00000108576 "Solute carrier family 6 member 4" P31645 17 30194319-30236002 "FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Neurotransmitter transport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "intestine: 38.0;lung: 27.2;placenta: 17.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 250.2;Enterocytes: 155.5;Migrating cytotrophoblasts: 71.7;Platelets: 63.3;Respiratory ionocytes: 35.6;Syncytiotrophoblasts: 146.7;Vascular endothelial cells: 41.9" "Cell type enhanced" "Detected in many" "splatter: 6.2" "Cancer enhanced" "Detected in some" "Breast Invasive Carcinoma (TCGA): 4.6" "Group enriched" "Detected in many" 11 "midbrain: 507.8;pons: 183.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "colorectal cancer: 2.5;liver cancer: 1.4" "Adipose visceral - Mesothelial cells, Pancreas - Alpha cells, Testis - Early spermatids" "Region enriched" "Detected in some" 4 "midbrain: 58.4" "Group enriched" "Detected in some" 8 "midbrain: 51.2;pons: 38.2" "HPA054723, HPA071354, HPA074728" Supported Supported Supported "Golgi apparatus,Vesicles" NA NA "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 8 "Golgi apparatus, Vesicles" "HPA054723: , HPA071354: , HPA074728: " "unprognostic (1.47e-1)" "unprognostic (1.51e-1)" "unprognostic (1.81e-1)" "unprognostic (3.90e-1)" "unprognostic (6.77e-2)" "potential prognostic favorable (6.64e-4)" "unprognostic (3.99e-3)" "unprognostic (8.98e-2)" "unprognostic (2.54e-2)" SLC6A5 "GlyT-2, GLYT2, NET1" ENSG00000165970 "Solute carrier family 6 member 5" Q9Y345 11 20599594-20659285 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Early spermatids: 27.6;Lactotrophs: 39.6;Late spermatids: 114.0;Oocytes: 9.2" "Cell type enriched" "Detected in some" 5 "cerebellar inhibitory: 69.6" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "medulla oblongata: 46.3;pons: 42.5;spinal cord: 15.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Uterine cancer: 1.9" "Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in some" 9 "pons and medulla: 49.3" "Group enriched" "Detected in many" 8 "medulla oblongata: 37.4;spinal cord: 22.5" CAB079052 Supported NA NA "Cluster 43: Hindbrain - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 19 "CAB079052: " SLC6A6 TAUT ENSG00000131389 "Solute carrier family 6 member 6" P31641 3 14402576-14489349 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 133.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 1099.2;Conjunctival goblet cells: 337.9;Endometrial glandular cells: 344.0;Neutrophils: 1043.7;Retinal pigment epithelial cells: 289.9;Rod photoreceptor cells: 1193.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "neutrophil: 56.9" "Lineage enriched" "Detected in all" 5 "granulocytes: 56.9" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015028, HPA016488" Enhanced Approved "Cell Junctions,Cytosol" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 47: Endothelial cells - Vasculature" "Cluster 7: Liver cancer - Metabolism" "Cluster 24: Neutrophils - Innate immunity signal integration" 3 "Cell Junctions, Cytosol" "HPA015028: , HPA016488: " "unprognostic (4.00e-2)" "unprognostic (7.15e-3)" "unprognostic (3.01e-1)" "unprognostic (1.83e-2)" "unprognostic (1.33e-1)" "unprognostic (1.25e-1)" "unprognostic (1.44e-3)" "unprognostic (8.34e-2)" "unprognostic (2.33e-1)" "unprognostic (3.06e-1)" "unprognostic (1.57e-1)" "unprognostic (6.88e-3)" "unprognostic (2.51e-1)" "potential prognostic unfavorable (4.31e-5)" "unprognostic (1.19e-1)" "unprognostic (8.66e-3)" "unprognostic (6.24e-2)" "unprognostic (4.29e-2)" "unprognostic (9.33e-2)" "unprognostic (8.83e-2)" "unprognostic (6.92e-2)" "unprognostic (7.30e-3)" "unprognostic (1.22e-1)" "unprognostic (2.21e-2)" "unprognostic (1.49e-1)" "unprognostic (2.54e-3)" "unprognostic (1.22e-2)" "unprognostic (7.90e-2)" "unprognostic (2.34e-1)" "unprognostic (4.84e-2)" "unprognostic (6.29e-2)" SLC6A7 PROT ENSG00000011083 "Solute carrier family 6 member 7" Q99884 5 150190062-150222788 "Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Neurotransmitter transport, Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "brain: 67.7" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 52.2;Brain inhibitory neurons: 10.1;Cardiomyocytes: 21.1;Colonocytes: 32.4;Enteric stem cells: 21.5;Enteric transient amplifying cells: 15.6;Goblet cells: 26.9;Myonuclei: 11.4;Neuroendocrine cells: 18.2;Other brain neurons: 14.2;Thymic myoid cells: 21.8;Tuft cells: 11.5" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in single" "Colon Adenocarcinoma (TCGA): 1.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "colorectal cancer: 1.8" "Colon - Colon enterocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA028907, HPA063773" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 53: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 2: Cerebellar granular cells - Neuronal signaling" "Plasma membrane, Cytosol" "HPA028907: , HPA063773: " "unprognostic (3.76e-1)" "unprognostic (7.44e-2)" "unprognostic (6.80e-2)" "unprognostic (2.31e-3)" SLC6A8 "CRT, CRT-1, CRT1, CRTR, CT1" ENSG00000130821 "Solute carrier family 6 member 8" P48029 X 153687926-153696588 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 179.3;Enterocytes: 230.3;Esophageal apical cells: 128.5;Pancreatic acinar cells: 417.8;Syncytiotrophoblasts: 124.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Lung - Smooth muscle cells, Testis - Sertoli cells" NA NA "Cluster 52: Non-specific - Cellular respiration" "Cluster 11: White matter - Signal transduction" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 32 "unprognostic (3.61e-3)" "unprognostic (7.33e-2)" "unprognostic (4.09e-2)" "unprognostic (6.66e-2)" "unprognostic (2.28e-1)" "unprognostic (2.38e-2)" "unprognostic (6.40e-2)" "unprognostic (3.65e-1)" "unprognostic (1.80e-1)" "unprognostic (1.63e-1)" "unprognostic (3.51e-2)" "unprognostic (2.18e-1)" "unprognostic (1.44e-1)" "unprognostic (2.21e-2)" "potential prognostic unfavorable (8.16e-4)" "unprognostic (5.07e-3)" "unprognostic (6.80e-2)" "unprognostic (6.24e-2)" "unprognostic (1.82e-3)" "unprognostic (1.44e-1)" "unprognostic (4.61e-1)" "unprognostic (7.13e-2)" "unprognostic (5.95e-2)" "unprognostic (6.30e-2)" "unprognostic (1.44e-1)" "unprognostic (4.81e-2)" "unprognostic (2.83e-1)" "unprognostic (3.70e-1)" "unprognostic (2.49e-1)" "potential prognostic unfavorable (8.27e-5)" "unprognostic (2.92e-1)" SLC6A9 "GlyT-1, GLYT1" ENSG00000196517 "Solute carrier family 6 member 9" P48067 1 43991500-44031467 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Neurotransmitter transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 76.8;skin 1: 43.4" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 53.3;Cone photoreceptor cells: 35.2;Epicardial cells: 95.5;Esophageal basal cells: 34.9;Retinal bipolar cells: 35.2;Retinal pigment epithelial cells: 51.2;Suprabasal keratinocytes: 35.9" "Cell type enhanced" "Detected in all" "astrocyte: 47.8;ependymal cell: 42.6;oligodendrocyte: 39.8" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 51.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skeletal muscle - Fibroblasts, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013977 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 68: Non-specific - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 13: Non-specific - Mixed function" "Cluster 110: Mural cells - ECM organization" 1 "Golgi apparatus" Nucleoplasm "HPA013977: " "unprognostic (1.57e-3)" "unprognostic (9.60e-2)" "unprognostic (3.34e-1)" "unprognostic (3.05e-1)" "unprognostic (1.30e-1)" "unprognostic (1.26e-1)" "unprognostic (2.37e-1)" "unprognostic (1.77e-2)" "unprognostic (1.37e-2)" "unprognostic (2.36e-3)" "unprognostic (1.57e-1)" "unprognostic (2.31e-2)" "unprognostic (6.21e-2)" "unprognostic (2.87e-2)" "unprognostic (8.60e-2)" "unprognostic (1.30e-1)" "unprognostic (3.77e-2)" "unprognostic (5.59e-2)" "unprognostic (1.74e-2)" "unprognostic (2.46e-1)" "unprognostic (9.61e-2)" "unprognostic (9.45e-3)" "unprognostic (3.15e-1)" "unprognostic (2.12e-3)" "unprognostic (1.29e-1)" "unprognostic (4.22e-2)" "potential prognostic unfavorable (7.47e-4)" "unprognostic (1.47e-2)" "unprognostic (1.09e-1)" "unprognostic (2.75e-1)" "unprognostic (1.49e-1)" SLC7A1 "ATRC1, CAT-1, ERR, HCAT1, REC1L" ENSG00000139514 "Solute carrier family 7 member 1" P30825 13 29509414-29595688 "Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 52.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 337.0;Endometrial glandular cells: 257.7;Epididymal basal cells: 263.6;Esophageal basal cells: 308.4;Salivary myoepithelial cells: 270.4" "Cell type enriched" "Detected in all" 16 "endothelial cell: 1091.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039721, HPA077838" Approved NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 104: Brain endothelial cells - Blood brain barrier" 112 "HPA039721: , HPA077838: " "unprognostic (5.86e-2)" "unprognostic (1.78e-1)" "unprognostic (2.10e-1)" "unprognostic (1.21e-3)" "unprognostic (4.11e-1)" "unprognostic (9.77e-3)" "unprognostic (1.18e-2)" "unprognostic (6.89e-2)" "unprognostic (3.53e-2)" "unprognostic (5.12e-2)" "unprognostic (4.24e-1)" "unprognostic (1.15e-1)" "potential prognostic unfavorable (8.76e-4)" "unprognostic (3.05e-3)" "unprognostic (2.93e-2)" "unprognostic (1.12e-2)" "potential prognostic unfavorable (1.10e-4)" "unprognostic (2.97e-2)" "unprognostic (3.51e-1)" "unprognostic (2.48e-2)" "unprognostic (3.16e-1)" "unprognostic (1.09e-1)" "unprognostic (1.45e-2)" "unprognostic (2.43e-2)" "unprognostic (3.07e-2)" "unprognostic (1.12e-1)" "unprognostic (7.14e-2)" "unprognostic (4.06e-2)" "unprognostic (4.25e-1)" "unprognostic (2.55e-1)" "unprognostic (3.37e-2)" SLC7A10 asc-1 ENSG00000130876 "Solute carrier family 7 member 10" Q9NS82 19 33208664-33225850 "Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "adipose tissue: 30.2;brain: 20.1;breast: 13.0" "Group enriched" "Detected in some" 4 "Adipocytes: 47.1;Astrocytes: 58.8;Bergmann glia: 28.6;Oligodendrocyte progenitor cells: 20.2;Retinal pigment epithelial cells: 42.6" "Group enriched" "Detected in some" 23 "astrocyte: 67.4;Bergmann glia: 29.2;oligodendrocyte precursor cell: 24.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 1.5;Gastric cancer: 1.1" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Minor Salivary Gland - Adipocytes (Minor salivary gland), Skin - Adipocytes (Skin)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041884, HPA057036" Uncertain Uncertain Nucleoplasm,Nucleoli NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 18: Liver cancer - Metabolism" "Cluster 89: Adipocytes - Lipid metabolism" 1 "Nucleoplasm, Nucleoli" "HPA041884: , HPA057036: " "potential prognostic favorable (5.74e-4)" "unprognostic (2.15e-1)" "unprognostic (1.34e-2)" "unprognostic (3.97e-1)" "unprognostic (3.14e-2)" "unprognostic (6.72e-3)" "unprognostic (3.23e-1)" SLC7A11 xCT ENSG00000151012 "Solute carrier family 7 member 11" Q9UPY5 4 138164097-138242349 "FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.7" "Cell type enhanced" "Detected in many" "Astrocytes: 423.8;Bergmann glia: 341.2;cDC: 119.4;Ependymal cells: 304.9;Foveolar cells: 335.6;Pancreatic acinar cells: 171.5;pDCs: 148.6" "Group enriched" "Detected in all" 5 "astrocyte: 553.7;Bergmann glia: 403.5;endothelial cell: 396.4;ependymal cell: 367.3;fibroblast: 1249.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in all" 4 "Gallbladder cancer: 158.2" "Liver - Vascular endothelial cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064215 Approved Vesicles NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 78: Brain - Neuronal signaling" "Cluster 39: Astrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 28: Astrocytes - Homeostasis & neuron support" 35 Vesicles "HPA064215: " "unprognostic (9.99e-2)" "unprognostic (9.72e-3)" "unprognostic (2.12e-1)" "unprognostic (1.45e-2)" "unprognostic (1.97e-1)" "unprognostic (1.74e-1)" "unprognostic (3.54e-1)" "potential prognostic unfavorable (4.09e-4)" "unprognostic (1.30e-2)" "unprognostic (1.47e-3)" "potential prognostic unfavorable (2.10e-6)" "validated prognostic unfavorable (1.97e-8)" "validated prognostic unfavorable (5.22e-4)" "unprognostic (3.44e-3)" "unprognostic (2.12e-2)" "unprognostic (2.05e-1)" "unprognostic (1.09e-1)" "unprognostic (6.45e-3)" "unprognostic (2.27e-1)" "unprognostic (1.73e-2)" "unprognostic (3.76e-2)" "unprognostic (1.14e-1)" "unprognostic (2.19e-2)" "unprognostic (7.64e-2)" "unprognostic (1.16e-2)" "unprognostic (1.75e-2)" "unprognostic (1.12e-1)" "unprognostic (7.98e-3)" "unprognostic (7.07e-2)" SLC7A13 "AGT-1, XAT2" ENSG00000164893 "Solute carrier family 7 member 13" Q8TCU3 8 86214063-86321146 "Predicted membrane proteins, Transporters" "Amino-acid transport, Antiport, Transport" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 232 "kidney: 39.2" "Cell type enriched" "Detected in some" 5 "Proximal tubule cells: 23.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Kidney Renal Papillary Cell Carcinoma (TCGA): 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 27: Breast cancer - Unknown function" "Cluster 88: Proximal tubular cells - Transmembrane transport" "unprognostic (3.82e-1)" "unprognostic (2.55e-2)" SLC7A14 "KIAA1613, PPP1R142" ENSG00000013293 "Solute carrier family 7 member 14" Q8TBB6 3 170459548-170586075 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 15.0;pituitary gland: 6.7;retina: 5.7" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 63.8;Brain excitatory neurons: 101.5;Brain inhibitory neurons: 82.2;Corticotrophs: 62.8;Gonadotrophs: 408.3;Lactotrophs: 54.8;Oligodendrocytes: 103.9;Other brain neurons: 102.0;Pancreatic islet cells: 62.0;Retinal amacrine cells: 54.3;Retinal horizontal cells: 76.1;Somatotrophs: 64.3;Thyrotrophs: 135.2" "Cell type enhanced" "Detected in all" "hippocampal dentate gyrus: 291.6" "Cancer enhanced" "Detected in single" "Glioblastoma Multiforme (TCGA): 1.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Neuroblastoma: 10.1" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pituitary gland - Gonadotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045929 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 41 "Vesicles, Cytosol" "Nucleoplasm, Plasma membrane" "HPA045929: " "unprognostic (6.17e-2)" "potential prognostic favorable (7.28e-4)" SLC7A2 "ATRC2, CAT-2, HCAT2" ENSG00000003989 "Solute carrier family 7 member 2" P52569 8 17497088-17570573 "Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 165.3;parathyroid gland: 210.8" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 574.1;Endometrial luminal cells: 257.0;Epicardial cells: 482.1;Fallopian secretory cells: 278.6;Fallopian tube ciliated cells: 329.1;Hepatocytes: 379.7;Myonuclei: 662.0;Pancreatic acinar cells: 609.1;Pancreatic islet cells: 621.3;Pericytes: 288.9;Vascular smooth muscle cells: 304.9" "Cell type enhanced" "Detected in many" "astrocyte: 94.1;fibroblast: 129.3" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 55.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009277 Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 76: Non-specific - Metabolism" "Cluster 8: Immune cells - Immune response" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 51: Secretory epithelial cells - Mixed function" 5 "Plasma membrane" "Cell Junctions" "HPA009277: " "unprognostic (2.64e-2)" "unprognostic (1.34e-1)" "unprognostic (1.10e-2)" "unprognostic (1.59e-1)" "unprognostic (6.90e-3)" "unprognostic (1.99e-1)" "unprognostic (1.21e-1)" "unprognostic (2.14e-2)" "unprognostic (4.34e-3)" "unprognostic (4.32e-2)" "unprognostic (1.08e-2)" "unprognostic (1.29e-2)" "unprognostic (1.27e-2)" "unprognostic (1.17e-1)" "unprognostic (2.72e-1)" "unprognostic (4.98e-2)" "unprognostic (6.61e-2)" "unprognostic (8.49e-2)" "unprognostic (2.96e-1)" "unprognostic (3.73e-1)" "unprognostic (1.26e-2)" "unprognostic (8.72e-2)" "unprognostic (2.27e-2)" "unprognostic (1.19e-2)" "unprognostic (9.94e-2)" "unprognostic (3.59e-2)" "potential prognostic unfavorable (1.16e-4)" "unprognostic (4.95e-2)" "unprognostic (2.59e-1)" "unprognostic (5.91e-2)" SLC7A3 "ATRC3, CAT-3, FLJ14541" ENSG00000165349 "Solute carrier family 7 member 3" Q8WY07 X 70925579-70931125 "FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 18.4" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 2.6;Early spermatids: 8.3;Epididymal basal cells: 4.0;Granulosa cells: 2.4;Late primary spermatocytes: 7.5;Late spermatids: 3.1;Medullary thymic epithelial cells: 19.2;Other brain neurons: 4.9" "Cell type enhanced" "Detected in some" "LAMP5-LHX6 and Chandelier: 10.4" "Cancer enriched" "Detected in some" 9 "Testicular Germ Cell Tumor (TCGA): 60.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 17 "testis cancer: 142.1" "Pituitary gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 80: Thymus - Adaptive immune response" "Cluster 38: Sub-cortical - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 6 "unprognostic (3.35e-1)" "unprognostic (1.07e-1)" "unprognostic (2.49e-2)" "unprognostic (1.75e-1)" "unprognostic (1.77e-1)" "unprognostic (2.41e-2)" SLC7A4 "CAT-4, HCAT3, VH" ENSG00000099960 "Solute carrier family 7 member 4" O43246 22 21028718-21032840 "Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 13.2;testis: 14.6" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 2.7;Brain inhibitory neurons: 1.8;Choroid plexus epithelial cells: 1.1;Endometrial luminal cells: 2.8;Ependymal cells: 1.1;Epicardial cells: 2.3;Other brain neurons: 5.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 3.6" "Adipose visceral - Mesothelial cells, Liver - Hepatic stellate cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA031023 Enhanced Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 1: Neurons - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" "Vesicles, Plasma membrane" Nucleoplasm "HPA031023: " "unprognostic (1.39e-3)" "potential prognostic favorable (2.63e-4)" "unprognostic (1.50e-2)" "unprognostic (9.52e-2)" "unprognostic (2.12e-2)" "unprognostic (1.24e-1)" "unprognostic (1.59e-2)" "unprognostic (4.35e-1)" "unprognostic (3.85e-2)" "unprognostic (5.91e-3)" "unprognostic (3.93e-2)" "unprognostic (1.08e-1)" "unprognostic (5.67e-2)" "unprognostic (2.07e-1)" "unprognostic (7.97e-3)" "unprognostic (6.70e-2)" "unprognostic (9.34e-2)" "unprognostic (4.80e-2)" "unprognostic (2.18e-1)" "unprognostic (2.16e-1)" "unprognostic (1.19e-1)" SLC7A5 "CD98, D16S469E, E16, LAT1, MPE16" ENSG00000103257 "Solute carrier family 7 member 5" Q01650 16 87830023-87869507 "Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 104.4;esophagus: 96.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 201.4;monocytes: 174.9;Neutrophils: 266.6;pDCs: 415.3;Plasma cells: 292.2;Retinal pigment epithelial cells: 400.7;Syncytiotrophoblasts: 203.2" "Cell type enriched" "Detected in all" 24 "endothelial cell: 994.5" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 327.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 10 "plasmacytoid DC: 17.2" "Lineage enriched" "Detected in many" 10 "dendritic cells: 17.2" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 1339.5" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052673, HPA056077" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA 76000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 104: Brain endothelial cells - Blood brain barrier" 21 "Plasma membrane, Cytosol" Vesicles "HPA052673: , HPA056077: " "unprognostic (1.29e-1)" "unprognostic (1.70e-3)" "unprognostic (2.80e-1)" "unprognostic (2.60e-2)" "unprognostic (8.42e-2)" "unprognostic (1.56e-2)" "unprognostic (4.18e-2)" "unprognostic (1.40e-1)" "unprognostic (1.15e-3)" "unprognostic (9.11e-2)" "validated prognostic unfavorable (9.58e-9)" "validated prognostic unfavorable (6.51e-5)" "potential prognostic unfavorable (6.71e-4)" "unprognostic (5.22e-2)" "unprognostic (2.87e-1)" "unprognostic (4.76e-3)" "unprognostic (3.57e-3)" "unprognostic (2.18e-2)" "unprognostic (3.06e-1)" "unprognostic (6.38e-2)" "unprognostic (2.81e-1)" "unprognostic (9.59e-2)" "potential prognostic unfavorable (7.45e-4)" "unprognostic (3.97e-1)" "unprognostic (2.46e-1)" "unprognostic (1.14e-1)" "unprognostic (2.05e-1)" "unprognostic (6.07e-2)" "unprognostic (9.05e-2)" "unprognostic (1.27e-3)" "unprognostic (7.44e-2)" SLC7A6 "KIAA0245, LAT-2, LAT3, y+LAT-2" ENSG00000103064 "Solute carrier family 7 member 6" Q92536 16 68264516-68301823 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Antiport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 67.0" "Cell type enhanced" "Detected in many" "Adipocytes: 306.6;Choroid plexus epithelial cells: 224.3;Myonuclei: 318.2;Syncytiotrophoblasts: 186.6;Thymic myoid cells: 738.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Spleen - B-cells (Spleen), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050713 Uncertain Uncertain "Vesicles,Plasma membrane" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 31 Vesicles "Plasma membrane" "HPA050713: " "unprognostic (7.85e-2)" "unprognostic (5.67e-3)" "unprognostic (5.86e-3)" "unprognostic (1.30e-1)" "unprognostic (3.20e-1)" "potential prognostic favorable (1.44e-4)" "unprognostic (2.12e-1)" "unprognostic (6.74e-3)" "unprognostic (1.05e-1)" "unprognostic (3.31e-1)" "unprognostic (5.27e-2)" "unprognostic (1.23e-1)" "unprognostic (1.28e-1)" "potential prognostic unfavorable (5.33e-4)" "unprognostic (1.62e-2)" "unprognostic (1.58e-1)" "unprognostic (1.21e-1)" "unprognostic (8.77e-2)" "unprognostic (4.79e-2)" "unprognostic (4.93e-2)" "unprognostic (4.21e-3)" "unprognostic (9.81e-2)" "unprognostic (4.66e-3)" "unprognostic (2.25e-2)" "unprognostic (2.20e-2)" "unprognostic (1.60e-1)" "unprognostic (1.74e-1)" "unprognostic (1.59e-1)" "unprognostic (2.87e-1)" "potential prognostic unfavorable (3.43e-4)" "unprognostic (2.45e-1)" SLC7A6OS "FLJ13291, Iwr1" ENSG00000103061 "Solute carrier family 7 member 6 opposite strand" Q96CW6 16 68284503-68310946 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 320.2;Cardiomyocytes: 636.3;Myonuclei: 155.9;Thymic myoid cells: 280.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041533 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 49: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 1 Nucleoplasm Cytosol "HPA041533: " "unprognostic (8.22e-3)" "unprognostic (5.17e-2)" "unprognostic (1.52e-1)" "unprognostic (1.80e-2)" "unprognostic (1.65e-2)" "unprognostic (1.13e-1)" "unprognostic (3.69e-1)" "unprognostic (1.03e-3)" "unprognostic (2.22e-2)" "unprognostic (4.12e-2)" "unprognostic (1.28e-1)" "unprognostic (2.73e-1)" "unprognostic (1.33e-2)" "potential prognostic unfavorable (5.18e-4)" "unprognostic (1.32e-1)" "unprognostic (1.51e-1)" "unprognostic (5.18e-2)" "unprognostic (5.22e-2)" "unprognostic (3.27e-2)" "unprognostic (1.64e-1)" "unprognostic (6.83e-2)" "unprognostic (1.92e-2)" "unprognostic (2.50e-3)" "potential prognostic unfavorable (1.82e-4)" "unprognostic (1.72e-1)" "unprognostic (9.20e-2)" "unprognostic (3.11e-2)" "unprognostic (7.40e-2)" "unprognostic (1.87e-1)" "unprognostic (1.18e-1)" "unprognostic (2.76e-1)" SLC7A7 "LPI, y+LAT-1" ENSG00000155465 "Solute carrier family 7 member 7" Q9UM01 14 22773222-22829820 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Disease variant, FDA approved drug targets, Osteoporosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 113.9;kidney: 253.4" "Cell type enhanced" "Detected in many" "Early spermatids: 133.6;Enterocytes: 428.4;Hofbauer cells: 219.9;Kupffer cells: 637.5;Late primary spermatocytes: 82.4;Macrophages: 128.8;Microglia: 83.1;monocytes: 198.5;Neutrophils: 120.4;Proximal tubule cells: 178.1" "Group enriched" "Detected in many" 12 "central nervous system macrophage: 102.4;leukocyte: 28.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 393.7;non-classical monocyte: 447.3" "Lineage enriched" "Detected in many" 5 "monocytes: 447.3" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Macrophages, Minor Salivary Gland - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA036227 Enhanced NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 72: Kidney - Transmembrane transport" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 4 "HPA036227: " "unprognostic (1.44e-1)" "unprognostic (1.27e-1)" "unprognostic (2.29e-1)" "unprognostic (2.59e-1)" "unprognostic (2.24e-1)" "unprognostic (2.27e-2)" "unprognostic (1.19e-2)" "unprognostic (2.12e-1)" "unprognostic (1.03e-1)" "unprognostic (1.78e-1)" "unprognostic (7.61e-2)" "unprognostic (1.38e-1)" "unprognostic (6.10e-2)" "unprognostic (4.85e-3)" "unprognostic (1.86e-1)" "unprognostic (2.58e-1)" "unprognostic (5.88e-2)" "unprognostic (3.59e-2)" "unprognostic (1.31e-1)" "unprognostic (3.62e-3)" "unprognostic (4.60e-1)" "unprognostic (2.02e-3)" "unprognostic (5.04e-2)" "unprognostic (1.20e-1)" "unprognostic (2.87e-3)" "unprognostic (3.50e-2)" "unprognostic (1.80e-1)" "unprognostic (3.58e-2)" "unprognostic (4.06e-2)" "unprognostic (2.54e-1)" "unprognostic (3.08e-1)" SLC7A8 "LAT2, LPI-PC1" ENSG00000092068 "Solute carrier family 7 member 8" Q9UHI5 14 23125295-23183674 "Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Antiport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 310.6" "Cell type enhanced" "Detected in many" "Epicardial cells: 334.3;Kupffer cells: 187.6;Podocytes: 395.7;Proximal tubule cells: 239.5;Thymic myoid cells: 137.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 8.3;eosinophil: 11.8" "Lineage enriched" "Detected in many" 4 "granulocytes: 11.8" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Pituitary gland - Somatotropes, Prostate - Prostate glandular cells, Skin - Inner root sheath cells, Spleen - Macrophages, Stomach - Gastric mucous cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046015, HPA051950, HPA060672" Enhanced NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 26 "CAB046015: , HPA051950: , HPA060672: " "unprognostic (7.06e-2)" "unprognostic (1.53e-1)" "unprognostic (1.11e-1)" "unprognostic (6.50e-2)" "unprognostic (1.72e-1)" "potential prognostic favorable (6.24e-4)" "unprognostic (2.73e-2)" "unprognostic (3.74e-1)" "unprognostic (5.10e-2)" "unprognostic (1.86e-1)" "unprognostic (3.78e-3)" "unprognostic (8.90e-2)" "unprognostic (3.91e-2)" "unprognostic (8.78e-3)" "unprognostic (2.22e-1)" "unprognostic (1.84e-3)" "unprognostic (8.10e-2)" "unprognostic (2.21e-2)" "unprognostic (1.94e-2)" "unprognostic (2.82e-2)" "unprognostic (3.94e-2)" "potential prognostic favorable (7.04e-4)" "unprognostic (3.00e-1)" "unprognostic (2.57e-1)" "unprognostic (2.58e-1)" "unprognostic (7.84e-3)" "unprognostic (6.01e-2)" "unprognostic (1.25e-2)" "unprognostic (3.08e-2)" "unprognostic (2.95e-1)" "unprognostic (2.61e-1)" SLC7A9 CSNU3 ENSG00000021488 "Solute carrier family 7 member 9" P82251 19 32830509-32869767 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Cystinuria, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "intestine: 122.3;kidney: 63.7" "Cell type enriched" "Detected in many" 9 "Enterocytes: 878.5" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in some" 8 "Kidney Renal Clear Cell Carcinoma (TCGA): 14.3;Kidney Renal Papillary Cell Carcinoma (TCGA): 7.2;Liver Hepatocellular Carcinoma (TCGA): 12.6;Stomach Adenocarcinoma (TCGA): 3.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 1.4;liver cancer: 3.5" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA042591 Enhanced NA NA "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 1: Enterocytes - Absorption and Digestion" 1 "HPA042591: " "unprognostic (1.79e-1)" "unprognostic (1.64e-1)" "potential prognostic favorable (7.00e-7)" "unprognostic (6.63e-3)" "unprognostic (6.61e-2)" "unprognostic (6.90e-2)" "unprognostic (1.29e-1)" "unprognostic (3.09e-2)" "unprognostic (2.02e-1)" "unprognostic (3.80e-1)" "unprognostic (5.11e-2)" "unprognostic (4.07e-1)" SLC8A1 NCX1 ENSG00000183023 "Solute carrier family 8 member A1" P32418 2 40097270-40611053 "FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Sodium transport, Transport" Calmodulin-binding "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "heart muscle: 144.0" "Group enriched" "Detected in many" 4 "Cardiomyocytes: 14581.0;Neutrophils: 8664.3;Renal connecting tubule cells: 12731.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 39.9" "Group enriched" "Detected in many" 6 "granulocytes: 39.9;monocytes: 12.3" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Colon - Smooth muscle cells, Heart muscle - Cardiomyocytes, Kidney - Intercalated cells, Pituitary gland - Thyrotropes, Prostate - Smooth muscle cells, Spleen - Macrophages, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022694, HPA070007" Uncertain Supported "Nucleoplasm,Plasma membrane" "Intracellular and membrane" Transport NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 35: Non-specific - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 24: Neutrophils - Innate immunity signal integration" 3 "Nucleoplasm, Plasma membrane" "CAB022694: , HPA070007: " "unprognostic (2.25e-1)" "unprognostic (3.47e-1)" "unprognostic (1.84e-1)" "unprognostic (7.73e-2)" "unprognostic (1.04e-2)" "unprognostic (1.92e-1)" "unprognostic (1.60e-1)" "unprognostic (1.89e-1)" "potential prognostic favorable (3.46e-8)" "unprognostic (1.15e-2)" "unprognostic (3.74e-1)" "unprognostic (1.25e-1)" "unprognostic (6.08e-2)" "unprognostic (2.97e-2)" "unprognostic (1.10e-2)" "unprognostic (5.82e-2)" "unprognostic (2.80e-2)" "unprognostic (1.49e-3)" "unprognostic (5.72e-2)" "unprognostic (1.08e-1)" "unprognostic (1.12e-1)" "unprognostic (3.00e-1)" "unprognostic (8.96e-3)" "unprognostic (1.65e-2)" "unprognostic (3.68e-1)" "unprognostic (8.56e-3)" SLC8A2 "KIAA1087, NCX2" ENSG00000118160 "Solute carrier family 8 member A2" Q9UPR5 19 47428017-47471893 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Sodium transport, Transport" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "brain: 99.2" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 31.9;Brain excitatory neurons: 95.1;Brain inhibitory neurons: 35.1;Endometrial glandular cells: 22.6;Gonadotrophs: 69.3;Other brain neurons: 33.4;Pancreatic islet cells: 22.2;Retinal amacrine cells: 35.0;Retinal bipolar cells: 30.7" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Pancreatic Adenocarcinoma (TCGA): 3.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 3.6;thyroid cancer: 4.1" "Adrenal gland - Adrenal medulla cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050818, HPA054671" Enhanced NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 51: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 2: Cerebellar granular cells - Neuronal signaling" "HPA050818: , HPA054671: " "unprognostic (6.09e-2)" "unprognostic (6.74e-2)" "unprognostic (3.08e-1)" "unprognostic (4.06e-2)" "unprognostic (1.00e-2)" "unprognostic (7.27e-2)" SLC8A3 NCX3 ENSG00000100678 "Solute carrier family 8 member A3" P57103 14 70044215-70189480 "Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Sodium transport, Transport" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "brain: 8.6;retina: 9.4;skeletal muscle: 19.0;tongue: 8.7" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 83.0;Brain inhibitory neurons: 137.8;Hematopoietic stem cells: 188.3;Mast cells: 263.2;Myonuclei: 433.8;Oligodendrocyte progenitor cells: 175.8;Other brain neurons: 113.4;Platelets: 80.6;Retinal amacrine cells: 213.9;Retinal bipolar cells: 325.4;Retinal horizontal cells: 76.1;Thymic myoid cells: 148.2" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in single" 8 "Glioblastoma Multiforme (TCGA): 5.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 7.9" "Adipose subcutaneous - Mast cells, Adipose visceral - Mast cells, Adrenal gland - Adrenal medulla cells, Colon - Mast cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001669 Supported "Nucleoplasm,Centrosome,Cytosol,Acrosome,End piece" NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 46: Skeletal myocytes - Muscle structure & formation" "Cytosol, Acrosome, End piece" "Nucleoplasm, Centrosome" "HPA001669: " "unprognostic (3.64e-1)" "unprognostic (1.75e-3)" SLC8B1 "FLJ22233, NCKX6, NCLX, SLC24A6" ENSG00000089060 "Solute carrier family 8 member B1" Q6J4K2 12 113298759-113359493 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Sensory transduction, Sodium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 70.6" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 209.0;monocytes: 109.9;Somatotrophs: 337.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Somatotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040668 Approved NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" "HPA040668: " "unprognostic (1.41e-2)" "unprognostic (7.74e-2)" "unprognostic (6.63e-3)" "unprognostic (2.17e-1)" "unprognostic (5.33e-3)" "unprognostic (2.57e-2)" "unprognostic (1.03e-1)" "unprognostic (3.55e-2)" "unprognostic (3.38e-1)" "unprognostic (2.62e-3)" "unprognostic (1.43e-1)" "unprognostic (1.16e-1)" "unprognostic (1.00e-1)" "unprognostic (4.34e-2)" "unprognostic (1.85e-1)" "unprognostic (9.59e-3)" "unprognostic (1.30e-1)" "unprognostic (1.46e-2)" "unprognostic (2.70e-1)" "unprognostic (8.75e-2)" "unprognostic (8.19e-3)" "unprognostic (7.72e-2)" "unprognostic (2.46e-1)" "unprognostic (2.22e-2)" "unprognostic (1.13e-1)" "unprognostic (2.51e-3)" "unprognostic (5.16e-2)" "unprognostic (1.16e-1)" "unprognostic (3.25e-1)" SLC9A1 "APNH, NHE-1, NHE1, PPP1R143" ENSG00000090020 "Solute carrier family 9 member A1" P19634 1 27098809-27166981 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" Calmodulin-binding "Deafness, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 72.1;stomach 1: 62.3" "Cell type enhanced" "Detected in many" "Foveolar cells: 376.8;Neutrophils: 312.5" "Cell type enhanced" "Detected in all" "pericyte: 109.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Fibroblasts, Stomach - Gastric mucous cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022371, HPA048532, HPA052891" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA 8400 "Cluster 35: Neutrophils - Protein binding" "Cluster 60: Stomach - Digestion" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 20 "Plasma membrane" Nucleoplasm "CAB022371: , HPA048532: , HPA052891: " "unprognostic (2.30e-1)" "unprognostic (2.95e-3)" "unprognostic (9.51e-3)" "unprognostic (1.44e-2)" "unprognostic (1.85e-3)" "unprognostic (9.67e-2)" "unprognostic (1.47e-2)" "unprognostic (2.80e-2)" "unprognostic (7.15e-2)" "unprognostic (3.99e-2)" "unprognostic (1.28e-3)" "unprognostic (2.61e-2)" "unprognostic (1.59e-1)" "unprognostic (7.39e-3)" "unprognostic (1.87e-2)" "unprognostic (6.92e-2)" "unprognostic (8.64e-3)" "unprognostic (9.06e-2)" "unprognostic (1.12e-1)" "unprognostic (4.12e-3)" "unprognostic (4.52e-2)" "unprognostic (2.87e-2)" "unprognostic (1.29e-1)" "unprognostic (2.27e-1)" "unprognostic (1.35e-2)" "unprognostic (4.53e-1)" "unprognostic (3.02e-1)" "unprognostic (1.02e-1)" "unprognostic (2.65e-1)" "unprognostic (4.39e-2)" "unprognostic (2.52e-1)" SLC9A2 NHE2 ENSG00000115616 "Solute carrier family 9 member A2" Q9UBY0 2 102619553-102711355 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 19.4;stomach 1: 24.9" "Cell type enhanced" "Detected in many" "Colonocytes: 152.7;Enteric stem cells: 77.6;Enteric transient amplifying cells: 84.3;Foveolar cells: 150.5;Gastric chief cells: 120.1;Goblet cells: 72.8;Mucous neck cells: 191.7;Papillary tip epithelial cells: 67.3;Parietal cells: 76.0;Pituitary stem cells: 105.1;Prostatic glandular cells: 67.2;Renal collecting duct principal cells: 85.6;Renal connecting tubule cells: 81.5;Respiratory ionocytes: 86.4;Salivary duct cells: 73.7;Salivary ionocytes: 112.2;Tuft cells: 80.7;Urothelial cells: 111.2" "Cell type enhanced" "Detected in many" "endothelial cell: 56.7;hippocampal CA4: 53.0" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 12.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Minor Salivary Gland - Minor salivary gland ductal cells, Prostate - Prostate glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA035121, HPA035122" Approved Supported "Cell Junctions" NA NA "Cluster 17: Intestine - Digestion" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 2 "Cell Junctions" "HPA035121: , HPA035122: " "unprognostic (6.17e-2)" "unprognostic (1.45e-2)" "unprognostic (9.22e-2)" "unprognostic (5.34e-3)" "unprognostic (1.80e-1)" "unprognostic (2.88e-3)" "unprognostic (1.05e-1)" "unprognostic (3.62e-2)" "unprognostic (1.16e-1)" "unprognostic (1.46e-1)" "unprognostic (2.50e-1)" "unprognostic (5.65e-2)" "unprognostic (8.90e-3)" "unprognostic (2.52e-2)" "unprognostic (5.64e-3)" "unprognostic (1.19e-1)" "unprognostic (2.41e-3)" "unprognostic (1.64e-3)" "unprognostic (1.41e-1)" "unprognostic (6.76e-2)" SLC9A3 "NHE-3, NHE3" ENSG00000066230 "Solute carrier family 9 member A3" P48764 5 470456-524449 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "gallbladder: 42.6;intestine: 88.4;kidney: 64.4;stomach 1: 47.2" "Group enriched" "Detected in some" 4 "Epicardial cells: 50.0;Loop of henle epithelial cells: 135.2;Proximal tubule cells: 67.4" "Cell type enhanced" "Detected in some" "mammillary body: 4.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Stomach - Parietal cells" "Region enriched" "Detected in single" 14 "cerebellum: 4.1" "Low region specificity" "Detected in many" "HPA036493, HPA036669" Enhanced Supported "Plasma membrane" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 37: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 7 "Plasma membrane" "HPA036493: , HPA036669: " "unprognostic (2.49e-2)" "unprognostic (2.24e-2)" "unprognostic (8.23e-2)" "unprognostic (3.71e-1)" "unprognostic (2.05e-1)" "unprognostic (9.80e-2)" "unprognostic (3.33e-1)" "unprognostic (1.06e-3)" "unprognostic (2.15e-2)" "unprognostic (1.32e-2)" "unprognostic (1.77e-2)" "unprognostic (7.25e-2)" "potential prognostic favorable (7.69e-4)" "unprognostic (2.50e-2)" "unprognostic (4.05e-2)" "unprognostic (1.40e-1)" "unprognostic (4.69e-2)" "unprognostic (1.45e-1)" "unprognostic (1.14e-2)" "unprognostic (2.60e-3)" "unprognostic (2.51e-1)" "unprognostic (2.42e-2)" "unprognostic (1.28e-2)" "unprognostic (6.95e-2)" "unprognostic (1.07e-1)" "unprognostic (4.75e-1)" "unprognostic (5.21e-2)" "unprognostic (7.49e-2)" SLC9A3R1 "EBP50, NHERF, NHERF1" ENSG00000109062 "SLC9A3 regulator 1" O14745 17 74748628-74769353 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Wnt signaling pathway" "Disease variant, Osteoporosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 348.1" "Cell type enhanced" "Detected in many" "Enterocytes: 508.6;Esophageal apical cells: 681.6;Esophageal suprabasal cells: 576.3" "Cell type enhanced" "Detected in many" "astrocyte: 55.5;leukocyte: 75.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "breast cancer: 462.6" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Breast - Breast glandular cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Prostate - Prostate glandular cells, Spleen - T-cells, Stomach - Parietal cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001962, HPA009672, HPA027247" Enhanced Approved "Vesicles,Plasma membrane,Centriolar satellite,Centrosome,Basal body,Cytosol,Calyx" NA Yes 3700000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 12: Non-specific - Vasculature" "Cluster 27: Breast cancer - Unknown function" "Cluster 85: Squamous epithelial cells - Keratinization" 64 "Plasma membrane, Centriolar satellite" "Vesicles, Centrosome, Basal body, Cytosol, Calyx" "CAB001962: , HPA009672: , HPA027247: " "unprognostic (3.28e-2)" "unprognostic (7.70e-2)" "unprognostic (1.89e-1)" "unprognostic (2.86e-1)" "unprognostic (2.99e-2)" "unprognostic (4.92e-2)" "unprognostic (1.96e-2)" "unprognostic (8.46e-2)" "unprognostic (2.00e-1)" "unprognostic (2.27e-1)" "potential prognostic favorable (5.98e-4)" "unprognostic (3.87e-1)" "unprognostic (2.88e-3)" "validated prognostic unfavorable (4.49e-6)" "validated prognostic unfavorable (1.30e-8)" "unprognostic (1.38e-1)" "unprognostic (4.83e-2)" "unprognostic (1.32e-2)" "unprognostic (1.15e-1)" "unprognostic (8.18e-2)" "unprognostic (1.17e-1)" "unprognostic (4.21e-2)" "unprognostic (1.92e-1)" "unprognostic (1.04e-1)" "unprognostic (1.27e-2)" "unprognostic (1.12e-1)" "unprognostic (5.67e-2)" "unprognostic (6.41e-2)" "unprognostic (5.31e-2)" "unprognostic (2.69e-1)" "unprognostic (3.46e-3)" SLC9A3R2 "E3KARP, NHERF-2, SIP-1, TKA-1" ENSG00000065054 "SLC9A3 regulator 2" Q15599 16 2025356-2039026 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 571.9" "Cell type enhanced" "Detected in many" "Breast lactating cells: 199.5;Hepatocytes: 250.6;Lymphatic endothelial cells: 301.0;Respiratory secretory cells: 221.7;Vascular endothelial cells: 486.7" "Cell type enriched" "Detected in all" 4 "endothelial cell: 252.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.2;intermediate monocyte: 1.6;myeloid DC: 3.9;plasmacytoid DC: 2.9" "Group enriched" "Detected in many" 5 "dendritic cells: 3.9;monocytes: 2.2" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001672, HPA066520" Enhanced Supported "Plasma membrane" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 47: Endothelial cells - Vasculature" "Cluster 72: Neuronal - Signal transduction" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 67 "Plasma membrane" "HPA001672: , HPA066520: " "unprognostic (3.40e-2)" "unprognostic (4.46e-2)" "unprognostic (1.83e-1)" "unprognostic (1.08e-1)" "unprognostic (1.57e-2)" "unprognostic (1.51e-1)" "unprognostic (2.29e-3)" "unprognostic (4.48e-2)" "unprognostic (2.29e-1)" "unprognostic (1.34e-1)" "validated prognostic favorable (2.53e-7)" "validated prognostic favorable (2.67e-5)" "unprognostic (8.20e-2)" "unprognostic (5.91e-3)" "potential prognostic favorable (2.67e-4)" "unprognostic (1.72e-1)" "unprognostic (2.32e-1)" "potential prognostic unfavorable (8.15e-4)" "unprognostic (3.90e-1)" "unprognostic (6.08e-3)" "unprognostic (6.10e-2)" "unprognostic (1.46e-1)" "unprognostic (1.02e-3)" "unprognostic (8.02e-2)" "unprognostic (1.78e-1)" "unprognostic (3.41e-1)" "unprognostic (1.10e-2)" "unprognostic (5.69e-3)" "unprognostic (2.04e-1)" "unprognostic (4.41e-1)" "unprognostic (7.42e-2)" SLC9A4 NHE4 ENSG00000180251 "Solute carrier family 9 member A4" Q6AI14 2 102473226-102533972 "Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "stomach 1: 50.8" "Cell type enhanced" "Detected in some" "Breast lactating cells: 31.1;Foveolar cells: 58.0;Gastric chief cells: 134.3;Mucous neck cells: 170.1;Papillary tip epithelial cells: 26.6;Parietal cells: 99.0;Renal collecting duct principal cells: 66.9;Renal connecting tubule cells: 94.2" "Cell type enhanced" "Detected in some" "endothelial cell: 1.3;MGE interneuron: 1.3" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 6.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 2.5" "Skin - Eccrine sweat gland cells, Testis - Late spermatids" "Group enriched" "Detected in some" 18 "hippocampal formation: 10.6;olfactory bulb: 6.8" "Region enriched" "Detected in single" 4 "olfactory bulb: 1.3" HPA036096 Supported Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 60: Stomach - Digestion" "Cluster 9: Non-specific - Receptor signaling" "Cluster 32: Non-specific - Cell proliferation" "Cluster 97: Non-specific - Cellular respiration" 1 "Nucleoplasm, Plasma membrane" "HPA036096: " "unprognostic (2.34e-1)" "unprognostic (2.02e-1)" "unprognostic (9.61e-3)" "unprognostic (1.96e-1)" "unprognostic (1.08e-1)" "unprognostic (2.54e-1)" "unprognostic (3.06e-2)" "unprognostic (5.27e-2)" "unprognostic (2.93e-2)" "unprognostic (8.29e-2)" "unprognostic (3.39e-1)" "unprognostic (1.95e-1)" SLC9A5 NHE5 ENSG00000135740 "Solute carrier family 9 member A5" Q14940 16 67237683-67272191 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 15.1;lymphoid tissue: 17.8" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 17.5;Brain inhibitory neurons: 24.2;Breast lactating cells: 17.3;Cardiomyocytes: 69.8;Early primary spermatocytes: 43.8;Epicardial cells: 34.1;Retinal amacrine cells: 28.1;Retinal horizontal cells: 32.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041004, HPA041329" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 5: Spleen - Immune response" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 35: Neurons - Synaptic function & neurogenesis" 12 Cytosol "Plasma membrane" "HPA041004: , HPA041329: " "unprognostic (1.82e-1)" "unprognostic (5.60e-2)" "unprognostic (3.70e-1)" "unprognostic (1.37e-2)" "unprognostic (6.89e-2)" "unprognostic (2.64e-2)" "unprognostic (3.96e-2)" "unprognostic (1.30e-2)" "unprognostic (1.55e-1)" "unprognostic (4.10e-2)" "unprognostic (9.82e-3)" SLC9A6 "KIAA0267, NHE-6, NHE6" ENSG00000198689 "Solute carrier family 9 member A6" Q92581 X 135973841-136047269 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 36.5" "Cell type enriched" "Detected in many" 5 "Pituicytes/FSCs: 306.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Colon - Colon enteroendocrine cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059445, HPA059590" Enhanced Supported "Vesicles,Plasma membrane" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 14: Neurons - Synaptic function" "Cluster 36: Non-specific - mRNA processing" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 17 Vesicles "Plasma membrane" "HPA059445: , HPA059590: " "unprognostic (5.88e-3)" "unprognostic (1.95e-1)" "unprognostic (3.69e-1)" "unprognostic (1.87e-1)" "unprognostic (1.71e-1)" "unprognostic (1.90e-1)" "unprognostic (6.49e-2)" "potential prognostic favorable (8.20e-4)" "unprognostic (5.93e-2)" "potential prognostic unfavorable (3.25e-4)" "potential prognostic favorable (1.72e-7)" "unprognostic (8.06e-2)" "unprognostic (2.45e-1)" "unprognostic (1.53e-1)" "unprognostic (1.72e-3)" "unprognostic (1.18e-1)" "unprognostic (3.40e-2)" "unprognostic (1.51e-1)" "unprognostic (1.61e-1)" "unprognostic (6.01e-2)" "unprognostic (1.47e-1)" "unprognostic (2.69e-2)" "unprognostic (3.57e-1)" "unprognostic (3.65e-2)" "unprognostic (1.98e-2)" "unprognostic (1.57e-2)" "unprognostic (1.37e-1)" "unprognostic (3.34e-1)" "unprognostic (3.27e-1)" "unprognostic (1.41e-2)" "unprognostic (4.95e-2)" SLC9A7 "NHE-7, NHE7" ENSG00000065923 "Solute carrier family 9 member A7" Q96T83 X 46599251-46759118 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Potassium transport, Sodium transport, Transport" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.7" "Cell type enhanced" "Detected in many" "B-cells: 152.4;Brain inhibitory neurons: 156.2;Cardiomyocytes: 219.2;cDC: 148.3;Gonadotrophs: 259.7;Hematopoietic stem cells: 152.8;pDCs: 150.9;Somatotrophs: 136.3;Thyrotrophs: 138.5" "Cell type enhanced" "Detected in all" "medium spiny neuron: 295.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 2.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Colon enteroendocrine cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048938, HPA075385" Approved Supported Vesicles NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 78: Brain - Neuronal signaling" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 82: Dendritic cells - Antigen presentation" 2 Vesicles "HPA048938: , HPA075385: " "unprognostic (1.37e-1)" "unprognostic (9.13e-2)" "unprognostic (2.08e-2)" "unprognostic (5.98e-2)" "unprognostic (3.24e-2)" "unprognostic (1.32e-1)" "unprognostic (1.58e-2)" "unprognostic (1.75e-1)" "unprognostic (2.37e-2)" "unprognostic (7.79e-3)" "unprognostic (3.05e-1)" "unprognostic (2.09e-2)" "unprognostic (1.02e-1)" "unprognostic (1.31e-2)" "unprognostic (1.30e-1)" "unprognostic (2.45e-3)" "unprognostic (6.58e-3)" "unprognostic (3.49e-2)" "unprognostic (3.30e-2)" "unprognostic (7.42e-2)" "unprognostic (2.17e-1)" "unprognostic (6.81e-2)" "unprognostic (9.39e-2)" "unprognostic (1.18e-1)" "unprognostic (1.28e-1)" "unprognostic (5.84e-2)" "unprognostic (8.52e-2)" "unprognostic (2.39e-1)" "unprognostic (1.35e-1)" "unprognostic (1.90e-1)" "unprognostic (1.66e-1)" SLC9A8 "KIAA0939, NHE8" ENSG00000197818 "Solute carrier family 9 member A8" Q9Y2E8 20 49812713-49892242 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Antiport, Differentiation, Ion transport, Sodium transport, Spermatogenesis, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Neutrophil progenitors: 346.4;Neutrophils: 957.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate basal glandular cells, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB033682 Approved NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 7 "CAB033682: " "unprognostic (1.92e-2)" "unprognostic (7.12e-2)" "unprognostic (8.43e-3)" "unprognostic (2.62e-2)" "unprognostic (6.67e-2)" "unprognostic (9.11e-2)" "unprognostic (2.23e-1)" "unprognostic (3.16e-2)" "unprognostic (5.24e-2)" "unprognostic (3.98e-1)" "validated prognostic favorable (4.60e-5)" "validated prognostic favorable (9.17e-4)" "unprognostic (2.43e-1)" "unprognostic (3.96e-2)" "unprognostic (6.11e-2)" "unprognostic (2.65e-2)" "unprognostic (1.87e-1)" "unprognostic (1.09e-1)" "unprognostic (1.52e-1)" "unprognostic (3.27e-2)" "unprognostic (2.75e-1)" "unprognostic (1.86e-1)" "unprognostic (6.33e-3)" "unprognostic (8.43e-2)" "unprognostic (3.63e-2)" "unprognostic (2.86e-2)" "unprognostic (1.76e-1)" "unprognostic (9.07e-2)" "unprognostic (4.83e-1)" "unprognostic (1.49e-2)" "unprognostic (3.45e-1)" SLC9A9 "FLJ35613, NHE9" ENSG00000181804 "Solute carrier family 9 member A9" Q8IVB4 3 143265222-143848485 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" "Autism, Autism spectrum disorder, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Corticotrophs: 539.8;Fibro-adipogenic progenitors: 468.0;Hofbauer cells: 1255.6;Kupffer cells: 703.1;Macrophages: 830.7;Medullary thymic epithelial cells: 1572.1;Microglia: 1383.3;Oligodendrocytes: 467.9" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 1938.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Myeloma: 9.3" "Heart muscle - Fibroblasts, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058234 Approved NA NA 67000 "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 30: White matter - Myelination" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 3 "HPA058234: " "unprognostic (1.66e-1)" "unprognostic (1.15e-1)" "unprognostic (4.46e-1)" "unprognostic (4.30e-2)" "unprognostic (2.92e-2)" "unprognostic (3.77e-2)" "unprognostic (2.87e-1)" "unprognostic (2.00e-2)" "unprognostic (7.83e-2)" "unprognostic (2.51e-1)" "unprognostic (3.55e-2)" "unprognostic (2.46e-2)" "unprognostic (4.82e-2)" "unprognostic (8.18e-2)" "unprognostic (3.37e-2)" "unprognostic (5.44e-3)" "unprognostic (3.45e-2)" "potential prognostic favorable (9.15e-4)" "unprognostic (1.07e-1)" "potential prognostic unfavorable (8.49e-5)" "unprognostic (2.09e-1)" "unprognostic (1.31e-1)" "unprognostic (5.13e-2)" "unprognostic (1.08e-1)" "unprognostic (1.74e-1)" "unprognostic (2.26e-1)" "unprognostic (1.27e-1)" "unprognostic (1.53e-2)" "unprognostic (2.50e-2)" "unprognostic (9.28e-2)" "unprognostic (1.13e-1)" SLC9B1 "NHA1, NHEDC1" ENSG00000164037 "Solute carrier family 9 member B1" Q4ZJI4 4 102885048-103019719 "Essential proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Fertilization, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "testis: 37.8" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 100.4;Early spermatids: 138.4;Late primary spermatocytes: 507.4;Late spermatids: 154.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in some" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA035435 Supported "Cytosol,Acrosome,Principal piece" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 57: Testis - Spermatogenesis" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" "Cytosol, Acrosome" "Principal piece" "HPA035435: " "unprognostic (3.11e-2)" "unprognostic (6.05e-2)" "unprognostic (6.18e-3)" "unprognostic (1.74e-1)" "unprognostic (1.06e-1)" "unprognostic (5.07e-1)" SLC9B2 "FLJ23984, NHA2, NHEDC2" ENSG00000164038 "Solute carrier family 9 member B2" Q86UD5 4 103019868-103085829 "Predicted membrane proteins, Transporters" "Antiport, Hydrogen ion transport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 36.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 89.0;Hepatocytes: 79.9;Smooth muscle cells: 134.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 11.9" "Group enriched" "Detected in many" 5 "B-cells: 5.1;NK-cells: 11.9;T-cells: 6.4" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Skeletal muscle - Endothelial cells, Spleen - B-cells (Spleen)" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA047008 Uncertain Uncertain "Nucleoplasm,Cell Junctions" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 36: Brain & Liver - Signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 103: Non-specific - Basic cellular processes" 1 Nucleoplasm "Cell Junctions" "HPA047008: " "unprognostic (4.07e-2)" "unprognostic (1.25e-1)" "unprognostic (1.61e-1)" "unprognostic (1.22e-1)" "unprognostic (3.89e-2)" "unprognostic (2.98e-1)" "unprognostic (1.16e-1)" "unprognostic (1.89e-1)" "unprognostic (1.40e-3)" "unprognostic (1.04e-1)" "unprognostic (7.77e-2)" "unprognostic (5.99e-3)" "unprognostic (1.40e-2)" "unprognostic (8.12e-3)" "unprognostic (2.25e-2)" "unprognostic (2.86e-1)" "unprognostic (7.97e-3)" "unprognostic (1.31e-2)" "unprognostic (4.14e-2)" "unprognostic (8.90e-2)" "unprognostic (1.73e-1)" "unprognostic (1.27e-2)" "unprognostic (3.20e-2)" "unprognostic (4.79e-1)" "unprognostic (4.59e-2)" "unprognostic (1.55e-1)" "unprognostic (2.43e-2)" "unprognostic (2.37e-1)" SLC9C1 "NHE, SLC9A10" ENSG00000172139 "Solute carrier family 9 member C1" Q4G0N8 3 112140898-112294227 "Predicted membrane proteins, Transporters" "Antiport, Differentiation, Ion transport, Sodium transport, Spermatogenesis, Transport" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "skin 1: 2.0;testis: 7.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 35.6;Distal convoluted tubule cells: 44.1;Epicardial cells: 36.4;Late primary spermatocytes: 21.0;Papillary tip epithelial cells: 67.1;Proximal tubule cells: 22.4;Renal collecting duct intercalated cells: 41.3;Renal collecting duct principal cells: 128.8;Renal connecting tubule cells: 24.8" "Cell type enhanced" "Detected in many" "deep-layer near-projecting: 30.7;ependymal cell: 15.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 65: Non-specific - Unknown function" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 1 SLC9C2 "MGC43026, SLC9A11" ENSG00000162753 "Solute carrier family 9 member C2 (putative)" Q5TAH2 1 173500460-173603072 "Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "testis: 5.6" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 77.9;Cone photoreceptor cells: 95.2;Endometrial ciliated cells: 35.2;Ependymal cells: 326.4;Fallopian tube ciliated cells: 44.9;Respiratory ciliated cells: 121.6;Sertoli cells: 121.1" "Cell type enriched" "Detected in many" 4 "ependymal cell: 336.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells, Lung - Respiratory ciliated cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Testis - Early spermatids" "Low region specificity" "Detected in all" "HPA059122, HPA079529" Enhanced Supported "Nuclear speckles,Plasma membrane" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 47: Leukemia - Hemostasis" "Cluster 34: Ciliated cells - Cilia assembly & function" "Plasma membrane" "Nuclear speckles" "HPA059122: , HPA079529: " "unprognostic (1.40e-2)" "unprognostic (3.17e-1)" SLCO1A2 "OATP, OATP-A, OATP1A2, SLC21A3" ENSG00000084453 "Solute carrier organic anion transporter family member 1A2" P46721 12 21264600-21419594 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 15.0;choroid plexus: 7.0;liver: 7.5;salivary gland: 14.6" "Group enriched" "Detected in some" 8 "Oligodendrocytes: 530.1;Retinal pigment epithelial cells: 225.9" "Group enriched" "Detected in many" 4 "endothelial cell: 830.6;oligodendrocyte: 712.7" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 25.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Lung - Alveolar cells type 1, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA071152 Supported "Plasma membrane" No No "Cluster 21: Neutrophils - Unknown function" "Cluster 36: Brain & Liver - Signaling" "Cluster 11: White matter - Signal transduction" "Cluster 56: Non-specific - Sensory perception" "Cluster 104: Brain endothelial cells - Blood brain barrier" "Plasma membrane" "HPA071152: " "unprognostic (3.27e-1)" "unprognostic (3.32e-3)" "unprognostic (6.03e-2)" "unprognostic (6.78e-2)" "unprognostic (4.54e-2)" "potential prognostic favorable (5.43e-4)" "unprognostic (5.50e-2)" "unprognostic (3.28e-2)" "unprognostic (5.09e-2)" "unprognostic (9.29e-2)" "unprognostic (1.31e-2)" "unprognostic (2.64e-3)" "unprognostic (1.62e-2)" "unprognostic (6.77e-2)" "unprognostic (3.19e-2)" "unprognostic (3.67e-1)" "unprognostic (8.11e-2)" "unprognostic (1.15e-1)" "unprognostic (1.78e-2)" "unprognostic (2.11e-1)" "unprognostic (8.76e-2)" "unprognostic (2.70e-1)" "unprognostic (1.62e-1)" "unprognostic (4.51e-3)" "unprognostic (2.08e-1)" "unprognostic (3.61e-1)" SLCO1B1 "LST-1, OATP-C, OATP1B1, SLC21A6" ENSG00000134538 "Solute carrier organic anion transporter family member 1B1" Q9Y6L6 12 21131194-21239796 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 610 "liver: 502.3" "Cell type enriched" "Detected in some" 25 "Hepatocytes: 247.1" "Group enriched" "Detected in some" 4 "choroid plexus epithelial cell: 4.8;endothelial cell: 7.9;oligodendrocyte: 18.1" "Cancer enriched" "Detected in single" 84 "Liver Hepatocellular Carcinoma (TCGA): 67.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "testis cancer: 2.0" "Liver - Hepatocytes" "HPA050892, HPA073093" Supported Supported "Plasma membrane" NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 2 "Plasma membrane" "HPA050892: , HPA073093: " "unprognostic (2.85e-3)" "unprognostic (1.43e-3)" SLCO1B3 "OATP1B3, OATP8, SLC21A8" ENSG00000111700 "Solute carrier organic anion transporter family member 1B3" Q9NPD5 12 20810702-20916911 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Lipid transport, Transport" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "liver: 247.7" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 66.3" "Cell type enriched" "Detected in single" 24 "choroid plexus epithelial cell: 12.4" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 19.0" "Region enriched" "Detected in some" 30 "choroid plexus: 34.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 53.7" "Liver - Hepatocytes, Minor Salivary Gland - Minor salivary gland ductal cells" "HPA004943, HPA050892" Enhanced Supported "Plasma membrane" NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 36: Choroid plexus - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 93: Hepatocytes - Bile production & excretion" 3 "Plasma membrane" "HPA004943: , HPA050892: " "unprognostic (7.86e-2)" "unprognostic (9.05e-2)" "unprognostic (1.27e-1)" "unprognostic (5.82e-3)" "unprognostic (2.56e-3)" "unprognostic (2.10e-2)" "potential prognostic favorable (3.79e-4)" "unprognostic (2.25e-3)" "unprognostic (1.58e-1)" "unprognostic (4.28e-2)" "unprognostic (1.81e-1)" "unprognostic (2.68e-1)" "unprognostic (1.87e-2)" "unprognostic (2.57e-2)" "unprognostic (2.18e-2)" "unprognostic (1.70e-2)" "unprognostic (1.38e-2)" "unprognostic (2.43e-1)" SLCO1B3-SLCO1B7 "LST-3TM12, OATP1B3-1B7" ENSG00000257046 "SLCO1B3-SLCO1B7 readthrough" 12 20815674-21090245 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "breast: 20.3" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 170.9" "Cell type enriched" "Detected in single" 35 "choroid plexus epithelial cell: 24.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 3.7;Gallbladder cancer: 3.0" HPA050892 Uncertain NA NA "Cluster 55: Breast - Lactation" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 93: Hepatocytes - Bile production & excretion" "HPA050892: " SLCO1C1 "OATP-F, OATP1, OATP1C1, SLC21A14" ENSG00000139155 "Solute carrier organic anion transporter family member 1C1" Q9NYB5 12 20695332-20753386 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 19.6;choroid plexus: 16.3;pituitary gland: 7.7" "Cell type enhanced" "Detected in some" "Astrocytes: 315.5;Choroid plexus epithelial cells: 526.2;Pituicytes/FSCs: 1367.0;Retinal pigment epithelial cells: 370.9" "Cell type enhanced" "Detected in many" "astrocyte: 274.4;choroid plexus epithelial cell: 545.3" "Cancer enriched" "Detected in single" 19 "Glioblastoma Multiforme (TCGA): 9.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Fibroblasts, Stomach - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" "unprognostic (3.02e-1)" "unprognostic (3.16e-1)" SLCO2A1 "MATR1, OATP2A1, PGT, SLC21A2" ENSG00000174640 "Solute carrier organic anion transporter family member 2A1" Q92959 3 133932701-134052184 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 119.9" "Cell type enriched" "Detected in many" 6 "Vascular endothelial cells: 576.9" "Cell type enriched" "Detected in some" 8 "endothelial cell: 144.5" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "choroid plexus: 18.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "thyroid cancer: 14.2" "Adrenal gland - Endothelial cells, Liver - Vascular endothelial cells, Pituitary gland - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA013742 Enhanced NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" "HPA013742: " "unprognostic (4.83e-2)" "unprognostic (3.49e-3)" "unprognostic (4.74e-2)" "unprognostic (2.43e-1)" "unprognostic (1.02e-1)" "unprognostic (3.60e-1)" "unprognostic (2.77e-1)" "unprognostic (8.19e-2)" "unprognostic (6.38e-3)" "unprognostic (8.86e-3)" "validated prognostic favorable (7.38e-11)" "validated prognostic favorable (1.94e-4)" "unprognostic (2.73e-1)" "validated prognostic favorable (1.58e-4)" "validated prognostic favorable (1.03e-4)" "unprognostic (1.16e-1)" "unprognostic (1.11e-2)" "unprognostic (7.87e-3)" "unprognostic (1.23e-1)" "unprognostic (1.30e-2)" "unprognostic (9.06e-2)" "unprognostic (1.78e-2)" "unprognostic (6.81e-2)" "unprognostic (4.83e-2)" "unprognostic (2.34e-1)" "unprognostic (1.66e-1)" "unprognostic (3.38e-2)" "potential prognostic unfavorable (4.18e-4)" "unprognostic (2.67e-1)" "unprognostic (2.21e-1)" "unprognostic (7.01e-2)" SLCO2B1 "OATP-B, OATP2B1, SLC21A9" ENSG00000137491 "Solute carrier organic anion transporter family member 2B1" O94956 11 75100563-75206549 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 214.5" "Group enriched" "Detected in many" 4 "Hepatocytes: 263.8;Hofbauer cells: 262.9;Kupffer cells: 467.4;Macrophages: 421.7;Mast cells: 527.7;Microglia: 659.0" "Group enriched" "Detected in many" 7 "central nervous system macrophage: 847.1;endothelial cell: 577.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 19.3;liver cancer: 20.8" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Kidney - Macrophages, Liver - Hepatocytes, Lung - Macrophages, Minor Salivary Gland - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Spleen - Macrophages, Stomach - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020659 Uncertain NA NA "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 7: Liver cancer - Metabolism" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" "HPA020659: " "unprognostic (1.43e-1)" "unprognostic (2.81e-2)" "unprognostic (8.57e-2)" "unprognostic (2.16e-1)" "unprognostic (3.10e-1)" "unprognostic (3.14e-2)" "unprognostic (4.11e-1)" "unprognostic (9.73e-2)" "unprognostic (1.48e-1)" "unprognostic (2.32e-1)" "potential prognostic favorable (8.52e-5)" "unprognostic (4.03e-1)" "unprognostic (1.19e-1)" "unprognostic (3.89e-2)" "unprognostic (2.46e-3)" "unprognostic (6.56e-3)" "unprognostic (6.54e-2)" "unprognostic (2.20e-2)" "unprognostic (1.12e-1)" "unprognostic (5.24e-3)" "unprognostic (5.40e-2)" "unprognostic (1.95e-1)" "unprognostic (2.50e-1)" "unprognostic (1.69e-1)" "unprognostic (1.12e-1)" "unprognostic (2.61e-2)" "unprognostic (1.09e-1)" "unprognostic (1.35e-1)" "unprognostic (1.03e-2)" "unprognostic (1.91e-1)" "unprognostic (2.04e-1)" SLCO3A1 "OATP-D, OATP3A1, SLC21A11" ENSG00000176463 "Solute carrier organic anion transporter family member 3A1" Q9UIG8 15 91853708-92172435 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 38.5" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 868.3;Neutrophils: 2014.7;Ocular epithelial cells: 693.6;Oligodendrocytes: 800.4" "Cell type enhanced" "Detected in all" "oligodendrocyte: 1067.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells, Pituitary gland - Corticotropes, Spleen - Fibroblasts_1, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066327 Approved NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 70: DU4475 - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" "HPA066327: " "unprognostic (3.09e-1)" "unprognostic (4.31e-2)" "unprognostic (1.62e-1)" "unprognostic (3.70e-2)" "unprognostic (7.75e-2)" "unprognostic (8.68e-2)" "unprognostic (3.21e-2)" "unprognostic (3.45e-1)" "unprognostic (6.92e-2)" "potential prognostic favorable (2.46e-4)" "validated prognostic favorable (1.72e-4)" "validated prognostic favorable (7.02e-4)" "unprognostic (2.04e-1)" "unprognostic (2.92e-1)" "unprognostic (3.61e-2)" "unprognostic (2.34e-1)" "unprognostic (1.53e-1)" "unprognostic (2.59e-1)" "unprognostic (5.62e-2)" "unprognostic (6.00e-2)" "unprognostic (7.65e-2)" "unprognostic (4.60e-3)" "unprognostic (2.05e-2)" "unprognostic (2.28e-2)" "unprognostic (1.76e-1)" "unprognostic (1.64e-2)" "unprognostic (1.08e-1)" "unprognostic (2.38e-2)" "unprognostic (2.29e-1)" "unprognostic (8.25e-2)" "unprognostic (2.38e-1)" SLCO4A1 "OATP-E, OATP4A1, SLC21A12" ENSG00000101187 "Solute carrier organic anion transporter family member 4A1" Q96BD0 20 62642503-62685785 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 56.0" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 87.3;Esophageal apical cells: 157.7;Extravillous trophoblasts: 362.9;Melanocytes: 102.7;Rod photoreceptor cells: 54.6;Vascular endothelial cells: 83.4" "Cell type enriched" "Detected in many" 6 "endothelial cell: 70.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.6" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in some" 5 "cerebellum: 6.7" "Low region specificity" "Detected in all" "HPA030669, HPA030670" Uncertain Supported "Cell Junctions" NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 2 "Cell Junctions" "HPA030669: , HPA030670: " "unprognostic (1.73e-1)" "unprognostic (1.10e-1)" "unprognostic (6.50e-2)" "unprognostic (2.23e-1)" "unprognostic (1.83e-2)" "unprognostic (2.87e-1)" "potential prognostic unfavorable (8.87e-4)" "unprognostic (8.07e-2)" "unprognostic (1.05e-1)" "unprognostic (5.65e-2)" "unprognostic (6.49e-2)" "unprognostic (1.11e-1)" "unprognostic (1.72e-1)" "unprognostic (2.19e-2)" "unprognostic (2.44e-2)" "potential prognostic unfavorable (6.68e-5)" "unprognostic (1.92e-2)" "unprognostic (2.94e-2)" "unprognostic (1.59e-1)" "unprognostic (5.31e-3)" "unprognostic (2.55e-1)" "unprognostic (4.50e-2)" "unprognostic (1.07e-2)" "unprognostic (2.57e-1)" "unprognostic (3.42e-2)" "unprognostic (1.34e-2)" "unprognostic (1.26e-2)" "potential prognostic favorable (6.79e-4)" "unprognostic (3.38e-2)" "unprognostic (2.49e-1)" "unprognostic (6.64e-2)" SLCO4C1 "OATP-H, OATP4C1, OATPX, SLC21A20" ENSG00000173930 "Solute carrier organic anion transporter family member 4C1" Q6ZQN7 5 102233986-102296284 "Predicted membrane proteins, Transporters" "Differentiation, Ion transport, Spermatogenesis, Transport" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "kidney: 38.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 95.1;Loop of henle epithelial cells: 107.3;Monocyte progenitors: 65.0;Neutrophil progenitors: 285.9;Neutrophils: 197.7;NK-cells: 60.4;Pituitary stem cells: 41.1;Proximal tubule cells: 97.5" "Cell type enhanced" "Detected in many" "deep-layer near-projecting: 46.6;hippocampal CA4: 34.3;leukocyte: 34.9" "Group enriched" "Detected in many" 5 "Kidney Renal Clear Cell Carcinoma (TCGA): 32.0;Kidney Renal Papillary Cell Carcinoma (TCGA): 71.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 9.5;neutrophil: 9.8" "Group enriched" "Detected in many" 5 "granulocytes: 9.8;NK-cells: 2.6;T-cells: 3.8" "Cancer enhanced" "Detected in some" "Kidney cancer: 7.8" "Adrenal gland - Adrenal medulla cells, Liver - Hepatocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary gland ductal cells, Spleen - Neutrophils_2, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA058249 Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 72: Kidney - Transmembrane transport" "Cluster 53: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 5 "Plasma membrane" "Nucleoplasm, Cytosol" "HPA058249: " "unprognostic (2.44e-1)" "unprognostic (2.32e-1)" "unprognostic (3.04e-2)" "unprognostic (1.14e-1)" "potential prognostic favorable (3.80e-8)" "unprognostic (8.69e-2)" "unprognostic (3.99e-2)" "unprognostic (5.59e-3)" "unprognostic (2.19e-1)" "unprognostic (1.83e-3)" "unprognostic (1.35e-1)" "unprognostic (2.74e-1)" "unprognostic (6.71e-2)" "unprognostic (9.44e-2)" "unprognostic (1.33e-1)" "unprognostic (3.57e-2)" SLCO5A1 "OATP-J, OATP5A1, OATPRP4, SLC21A15" ENSG00000137571 "Solute carrier organic anion transporter family member 5A1" Q9H2Y9 8 69667046-69834978 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 6.1;skeletal muscle: 7.1;tongue: 10.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 133.8;cDC: 78.6;Corticotrophs: 271.0;Gonadotrophs: 295.1;Myonuclei: 603.7;Prostatic glandular cells: 166.2;Retinal amacrine cells: 108.8;Thyrotrophs: 94.9" "Cell type enhanced" "Detected in many" "LAMP5-LHX6 and Chandelier: 208.6;midbrain-derived inhibitory: 87.9" "Cancer enhanced" "Detected in some" "Prostate Adenocarcinoma (TCGA): 2.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 19.5" "Pituitary gland - Corticotropes, Prostate - Prostate glandular cells, Skeletal muscle - Skeletal myocytes, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells" "Group enriched" "Detected in some" 7 "basal ganglia: 2.3;olfactory bulb: 6.7" "Region enriched" "Detected in many" 7 "olfactory bulb: 17.5" HPA025062 Uncertain Supported "Vesicles,Plasma membrane" NA NA "Cluster 63: Non-specific - Basic cellular processes" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 55: Myocytes - Oxidative muscle function" 1 "Plasma membrane" Vesicles "HPA025062: " "unprognostic (2.16e-2)" "unprognostic (1.30e-2)" "unprognostic (1.39e-3)" "unprognostic (3.24e-2)" "unprognostic (1.75e-1)" "unprognostic (4.08e-2)" "unprognostic (4.22e-2)" "unprognostic (2.17e-1)" "unprognostic (1.26e-1)" SLCO6A1 "CT48, MGC26949, OATP6A1, OATPY" ENSG00000205359 "Solute carrier organic anion transporter family member 6A1" Q86UG4 5 102371774-102499016 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 109 "testis: 28.3" "Group enriched" "Detected in some" 10 "Early primary spermatocytes: 95.5;Early spermatids: 147.0;Late primary spermatocytes: 379.1" "Cell type enhanced" "Detected in some" "committed oligodendrocyte precursor: 2.1;oligodendrocyte: 4.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Region enhanced" "Detected in some" "hippocampal formation: 1.8" HPA054126 Enhanced NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 56: Non-specific - Sensory perception" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" "HPA054126: " SLF1 "ANKRD32, BRCTD1, BRCTx, DKFZp564C0469, DKFZp761C121" ENSG00000133302 "SMC5-SMC6 complex localization factor 1" Q9BQI6 5 94618669-94739436 "Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 7.2" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 169.7;Early primary spermatocytes: 222.8;Neutrophils: 152.5;Sertoli cells: 147.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040793, HPA054213" Uncertain Approved Nucleoplasm NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" 8 Nucleoplasm "HPA040793: , HPA054213: " "unprognostic (5.44e-2)" "unprognostic (3.21e-2)" "unprognostic (1.35e-1)" "unprognostic (6.54e-2)" "unprognostic (8.72e-2)" "unprognostic (1.32e-2)" "unprognostic (4.69e-1)" "unprognostic (5.11e-2)" "potential prognostic favorable (3.69e-4)" "unprognostic (1.04e-2)" "unprognostic (2.77e-1)" "potential prognostic unfavorable (8.22e-4)" "unprognostic (1.26e-1)" "unprognostic (3.26e-2)" "unprognostic (5.41e-2)" "unprognostic (1.52e-1)" "unprognostic (3.40e-2)" "potential prognostic unfavorable (9.37e-4)" "unprognostic (1.04e-1)" "unprognostic (5.12e-2)" "unprognostic (2.04e-1)" "unprognostic (1.21e-1)" "unprognostic (2.27e-1)" "unprognostic (1.52e-1)" "unprognostic (5.67e-2)" "unprognostic (7.29e-3)" SLF2 "C10orf6, FAM178A, FLJ10512, FLJ25012" ENSG00000119906 "SMC5-SMC6 complex localization factor 2" Q8IX21 10 100912963-100965134 "Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Leydig cells: 263.9;Oligodendrocytes: 250.8;Peritubular myoid cells: 233.3;Pituicytes/FSCs: 233.1;Pituitary stem cells: 278.4;Sertoli cells: 374.4;Somatotrophs: 233.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038499, HPA057568" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 21: Testis - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 94: Gonadal somatic cells - Mixed function" 20 "Nucleoplasm, Vesicles" "HPA038499: , HPA057568: " "unprognostic (1.06e-2)" "unprognostic (2.41e-2)" "unprognostic (1.57e-1)" "potential prognostic unfavorable (3.52e-4)" "unprognostic (5.53e-2)" "unprognostic (1.26e-1)" "unprognostic (8.73e-3)" "unprognostic (2.34e-3)" "unprognostic (1.44e-1)" "unprognostic (7.98e-2)" "unprognostic (5.07e-2)" "unprognostic (1.94e-1)" "unprognostic (2.20e-3)" "unprognostic (2.35e-2)" "unprognostic (1.14e-1)" "unprognostic (6.32e-2)" "unprognostic (1.37e-1)" "unprognostic (1.98e-1)" "unprognostic (7.80e-3)" "unprognostic (2.37e-2)" "potential prognostic unfavorable (2.26e-4)" "unprognostic (1.31e-1)" "unprognostic (3.66e-1)" "unprognostic (1.63e-1)" "unprognostic (1.66e-1)" "unprognostic (9.41e-2)" "unprognostic (1.19e-2)" "unprognostic (3.29e-2)" "unprognostic (3.82e-1)" SLFN11 FLJ34922 ENSG00000172716 "Schlafen family member 11" Q7Z7L1 17 35350305-35373701 "Predicted intracellular proteins" "Antiviral defense, DNA damage, Immunity" "DNA-binding, Endonuclease, Helicase, Hydrolase, Nuclease, RNA-binding, tRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 75.4;Epididymal principal cells: 93.5;Hofbauer cells: 81.5;Kupffer cells: 58.4;Macrophages: 68.0;Megakaryocyte progenitors: 58.9;Megakaryocyte-Erythroid progenitors: 58.1;Monocyte progenitors: 80.2;monocytes: 101.9;pDCs: 94.9;Plasma cells: 59.4;Respiratory deuterosomal cells: 69.5;Schwann cells: 55.8;Vascular smooth muscle cells: 58.7" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 44.3;endothelial cell: 78.6;fibroblast: 37.4;leukocyte: 46.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells, Colon - Endothelial cells, Prostate - Fibroblasts, Skin - Endothelial cells, Testis - Endothelial cells" "HPA023030, HPA062062" Uncertain Supported Nucleoplasm,Cytosol No NA "Cluster 13: Non-specific - Mitochondria" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 103: Non-specific - Basic cellular processes" 18 Nucleoplasm Cytosol "HPA023030: , HPA062062: " "unprognostic (4.07e-2)" "unprognostic (1.54e-1)" "unprognostic (2.73e-1)" "unprognostic (1.81e-1)" "unprognostic (3.65e-2)" "unprognostic (5.09e-2)" "potential prognostic unfavorable (5.72e-4)" "unprognostic (6.55e-3)" "unprognostic (1.20e-1)" "unprognostic (3.39e-2)" "unprognostic (1.04e-1)" "unprognostic (1.64e-1)" "unprognostic (1.25e-2)" "unprognostic (4.47e-2)" "unprognostic (8.90e-2)" "unprognostic (3.94e-2)" "unprognostic (6.53e-2)" "unprognostic (2.51e-2)" "unprognostic (3.79e-2)" "unprognostic (7.18e-2)" "unprognostic (2.44e-1)" "unprognostic (2.14e-1)" "unprognostic (4.80e-2)" "unprognostic (2.26e-1)" "unprognostic (3.54e-1)" "unprognostic (1.18e-1)" "unprognostic (5.94e-2)" "unprognostic (1.23e-1)" "unprognostic (4.10e-3)" "unprognostic (3.16e-2)" "unprognostic (1.07e-1)" SLFN12 FLJ10260 ENSG00000172123 "Schlafen family member 12" Q8IYM2 17 35410922-35433283 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial luminal cells: 24.1;Megakaryocytes: 30.9" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 27.3;endothelial cell: 52.6;leukocyte: 21.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 54.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" HPA022523 Uncertain NA NA "Cluster 41: Basophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 72: Neuronal - Signal transduction" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 9 "HPA022523: " "unprognostic (6.08e-2)" "unprognostic (8.32e-2)" "unprognostic (6.73e-2)" "unprognostic (2.62e-1)" "unprognostic (2.25e-1)" "unprognostic (1.29e-1)" "unprognostic (3.69e-2)" "unprognostic (5.74e-2)" "unprognostic (1.15e-1)" "unprognostic (1.82e-2)" "potential prognostic favorable (7.01e-4)" "unprognostic (9.90e-2)" "unprognostic (1.70e-1)" "unprognostic (7.14e-2)" "unprognostic (1.39e-2)" "unprognostic (3.07e-2)" "unprognostic (4.24e-2)" "unprognostic (7.13e-2)" "unprognostic (4.38e-2)" "unprognostic (8.00e-3)" "unprognostic (4.31e-3)" "unprognostic (1.42e-1)" "unprognostic (2.61e-1)" "unprognostic (6.34e-2)" "unprognostic (1.84e-1)" "unprognostic (9.53e-2)" "unprognostic (1.63e-2)" "unprognostic (1.04e-1)" "unprognostic (1.99e-1)" "unprognostic (3.16e-1)" SLFN12L ENSG00000205045 "Schlafen family member 12 like" 17 35464249-35537678 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 4.4" "Group enriched" "Detected in many" 4 "NK-cells: 325.5;T-cells: 270.1" "Group enriched" "Detected in some" 34 "endothelial cell: 99.4;leukocyte: 317.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Minor Salivary Gland - T-cells, Pancreas - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Stomach - T-cells, Thyroid gland - T-cells" HPA024447 Uncertain NA NA "Cluster 24: Non-specific - Transcription" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 9: Non-specific - Receptor signaling" "Cluster 59: Leukemia - T-cell receptor" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" "HPA024447: " "unprognostic (1.21e-1)" "unprognostic (1.56e-2)" "unprognostic (4.84e-1)" "unprognostic (1.53e-1)" "unprognostic (4.74e-2)" "unprognostic (1.55e-1)" "unprognostic (5.05e-3)" "unprognostic (7.55e-3)" "unprognostic (4.10e-2)" "unprognostic (1.49e-1)" SLFN13 FLJ31952 ENSG00000154760 "Schlafen family member 13" Q68D06 17 35435096-35448837 "Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 24.2;salivary gland: 30.6" "Cell type enhanced" "Detected in many" "Breast lactating cells: 141.6;Choroid plexus epithelial cells: 47.2;Endometrial ciliated cells: 88.2;Epididymal efferent duct ciliated cells: 59.6;Erythrocyte progenitors: 81.7;Fallopian tube ciliated cells: 129.3;Lacrimal acinar cells: 50.7;Neutrophil progenitors: 59.6;NK-cells: 93.6;Respiratory ciliated cells: 121.7;Salivary acinar cells: 70.7" "Group enriched" "Detected in some" 4 "choroid plexus epithelial cell: 32.1;endothelial cell: 31.5;leukocyte: 37.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 5.3" "Group enriched" "Detected in many" 4 "granulocytes: 4.5;NK-cells: 5.3" "Low cancer specificity" "Detected in many" "HPA022532, HPA023064" Uncertain Approved "Cytokinetic bridge" Yes No "Cluster 15: NK-cells - Unknown function" "Cluster 60: Stomach - Digestion" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 55: Lymphoma - Immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" "Cytokinetic bridge" "HPA022532: , HPA023064: " "unprognostic (2.94e-2)" "unprognostic (3.83e-1)" "unprognostic (5.30e-3)" "unprognostic (2.46e-2)" "unprognostic (1.97e-1)" "unprognostic (2.65e-2)" "unprognostic (3.94e-1)" "unprognostic (1.70e-1)" "unprognostic (2.72e-2)" "unprognostic (7.10e-2)" "potential prognostic favorable (1.62e-5)" "unprognostic (8.52e-2)" "unprognostic (4.15e-2)" "unprognostic (5.21e-2)" "potential prognostic unfavorable (6.49e-5)" "unprognostic (1.14e-1)" "unprognostic (1.59e-1)" "potential prognostic unfavorable (5.57e-5)" "unprognostic (4.22e-2)" "unprognostic (1.18e-1)" "unprognostic (7.50e-2)" "unprognostic (3.59e-3)" "unprognostic (1.55e-2)" "unprognostic (1.64e-1)" "unprognostic (9.25e-2)" "unprognostic (2.61e-1)" "unprognostic (6.22e-2)" "unprognostic (1.97e-1)" "unprognostic (2.10e-2)" "unprognostic (1.23e-1)" SLFN14 ENSG00000236320 "Schlafen family member 14" P0C7P3 17 35543985-35560819 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 5 "bone marrow: 3.9" "Cell type enriched" "Detected in some" 5 "Platelets: 156.9" "Cell type enhanced" "Detected in single" "leukocyte: 1.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "Leukemia: 2.3" "Kidney - T-cells, Prostate - T-cells, Stomach - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA022994, HPA023065" Uncertain NA NA "Cluster 15: Bone marrow - Innate immune response" "Cluster 6: Non-specific - Immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 47: Platelets - Hemostasis" "HPA022994: , HPA023065: " SLFN5 MGC19764 ENSG00000166750 "Schlafen family member 5" Q08AF3 17 35243071-35273655 "Predicted intracellular proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fallopian tube ciliated cells: 144.2;NK-cells: 176.0;Salivary ionocytes: 129.6;T-cells: 163.0" "Group enriched" "Detected in all" 5 "endothelial cell: 112.7;leukocyte: 202.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 24.7;MAIT T-cell: 30.7;memory CD4 T-cell: 30.8;memory CD8 T-cell: 28.9;naive CD4 T-cell: 37.6;naive CD8 T-cell: 31.3;NK-cell: 42.4;T-reg: 69.0" "Group enriched" "Detected in all" 7 "NK-cells: 42.4;T-cells: 69.0" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" HPA017760 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 1: T-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 30: White matter - Myelination" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 9: T-cells - Adaptive immunity: Regulation" 16 Nucleoplasm Vesicles "HPA017760: " "unprognostic (4.49e-3)" "unprognostic (2.13e-1)" "unprognostic (1.52e-1)" "unprognostic (1.39e-2)" "unprognostic (6.77e-2)" "unprognostic (2.09e-1)" "unprognostic (7.05e-2)" "unprognostic (1.89e-2)" "unprognostic (3.62e-3)" "unprognostic (1.06e-1)" "potential prognostic favorable (7.34e-4)" "unprognostic (8.54e-3)" "unprognostic (2.70e-2)" "unprognostic (8.46e-3)" "unprognostic (1.25e-1)" "unprognostic (2.68e-1)" "unprognostic (1.27e-2)" "unprognostic (2.98e-1)" "unprognostic (1.74e-1)" "unprognostic (6.19e-3)" "unprognostic (1.38e-3)" "potential prognostic unfavorable (7.48e-4)" "unprognostic (2.10e-2)" "unprognostic (1.97e-1)" "unprognostic (1.28e-2)" "unprognostic (4.07e-2)" "unprognostic (1.73e-1)" "unprognostic (1.26e-1)" "unprognostic (1.56e-1)" "unprognostic (2.01e-1)" "unprognostic (3.34e-1)" SLFNL1 FLJ23878 ENSG00000171790 "Schlafen like 1" Q499Z3 1 41015589-41023237 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "testis: 70.6" "Cell type enriched" "Detected in many" 4 "Late spermatids: 1283.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 9.2" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA054956 Approved Cytosol NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 48: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" Cytosol "HPA054956: " "unprognostic (5.01e-1)" "unprognostic (7.28e-2)" "unprognostic (1.03e-2)" "unprognostic (1.64e-1)" "unprognostic (1.10e-1)" "potential prognostic favorable (9.08e-4)" "unprognostic (1.97e-2)" "unprognostic (2.42e-1)" SLIRP "C14orf156, DC50" ENSG00000119705 "SRA stem-loop interacting RNA binding protein" Q9GZT3 14 77708071-77761104 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric progenitor cells: 698.5;Hepatocytes: 876.5;Late primary spermatocytes: 950.6;Parietal cells: 878.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020291 Approved Supported Mitochondria No Yes "Cluster 2: Dendritic cells - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 97: Non-specific - Cellular respiration" 31 Mitochondria "HPA020291: " "potential prognostic unfavorable (3.34e-5)" "unprognostic (2.03e-1)" "potential prognostic favorable (1.66e-5)" "unprognostic (2.11e-1)" "unprognostic (4.60e-2)" "unprognostic (4.03e-2)" "unprognostic (3.64e-1)" "unprognostic (1.16e-3)" "unprognostic (1.52e-2)" "unprognostic (7.36e-2)" "unprognostic (6.02e-2)" "unprognostic (3.27e-1)" "unprognostic (2.29e-2)" "unprognostic (2.07e-3)" "potential prognostic unfavorable (8.47e-4)" "unprognostic (1.96e-1)" "unprognostic (1.66e-2)" "unprognostic (1.52e-2)" "unprognostic (3.80e-3)" "unprognostic (9.15e-2)" "unprognostic (6.59e-2)" "unprognostic (9.51e-2)" "unprognostic (1.55e-1)" "unprognostic (1.06e-1)" "unprognostic (2.50e-1)" "unprognostic (1.24e-1)" "unprognostic (2.14e-1)" "unprognostic (3.09e-1)" "unprognostic (4.27e-2)" "unprognostic (2.85e-1)" SLIT1 "MEGF4, SLIL1, Slit-1, SLIT3" ENSG00000187122 "Slit guidance ligand 1" O75093 10 96998038-97185959 "Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 32.7;pituitary gland: 12.6" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 133.9;Brain inhibitory neurons: 56.7;Early spermatids: 104.8;Late spermatids: 74.9;Other brain neurons: 66.5;Somatotrophs: 500.5;Thyrotrophs: 317.7" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in some" 5 "Glioblastoma Multiforme (TCGA): 17.1;Thyroid Carcinoma (TCGA): 17.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Leukemia: 11.1;thyroid cancer: 8.6" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA006879 Approved "Plasma membrane" "Secreted in brain" "Developmental protein" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 35: Neurons - Synaptic function & neurogenesis" 9 "Plasma membrane" "HPA006879: " "unprognostic (4.64e-1)" "unprognostic (6.26e-3)" "unprognostic (2.30e-1)" "unprognostic (3.66e-2)" "unprognostic (1.00e-1)" "unprognostic (1.88e-1)" "unprognostic (2.27e-1)" SLIT2 "SLIL3, Slit-2" ENSG00000145147 "Slit guidance ligand 2" O94813 4 20251905-20620561 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Chemotaxis, Differentiation, Neurogenesis" "Developmental protein, Heparin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 1431.1;Choroid plexus epithelial cells: 824.3;Ependymal cells: 521.9;Epididymal basal cells: 499.2;Fibro-adipogenic progenitors: 641.0;Pituicytes/FSCs: 2043.1;Pituitary stem cells: 1119.8;Renal collecting duct intercalated cells: 1450.4;Retinal amacrine cells: 668.9" "Cell type enhanced" "Detected in all" "mammillary body: 1693.5;MGE interneuron: 1400.0" "Cancer enriched" "Detected in many" 5 "Kidney Chromophobe (TCGA): 37.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Lung - Fibroblasts_1, Pancreas - Fibroblasts, Prostate - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB007590, HPA019511, HPA023088" Uncertain "Secreted in other tissues" "Developmental protein" NA NA 170000 "Cluster 13: Lung - Secretion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 4 "CAB007590: , HPA019511: , HPA023088: " "unprognostic (2.27e-2)" "unprognostic (2.65e-1)" "unprognostic (2.51e-2)" "unprognostic (6.15e-2)" "unprognostic (2.16e-2)" "unprognostic (6.02e-2)" "unprognostic (2.89e-2)" "unprognostic (8.69e-2)" "unprognostic (1.54e-1)" "unprognostic (8.17e-2)" "unprognostic (9.66e-3)" "unprognostic (1.89e-2)" "unprognostic (1.48e-2)" "unprognostic (1.00e-1)" "unprognostic (1.74e-1)" "unprognostic (6.24e-2)" "unprognostic (1.12e-2)" "unprognostic (2.04e-1)" "unprognostic (1.16e-2)" "unprognostic (2.38e-1)" "unprognostic (1.13e-1)" "unprognostic (4.94e-2)" "unprognostic (4.79e-2)" "unprognostic (9.58e-3)" "unprognostic (7.45e-2)" "unprognostic (2.56e-1)" "unprognostic (2.47e-3)" "unprognostic (1.57e-2)" "unprognostic (2.07e-1)" "unprognostic (1.22e-1)" SLIT3 "MEGF5, SLIL2, Slit-3, SLIT1, slit2" ENSG00000184347 "Slit guidance ligand 3" O75094 5 168661733-169301139 "Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 586.7;Adrenal medulla cells: 712.7;Brain excitatory neurons: 566.7;Endometrial stromal cells: 339.7;Epicardial cells: 620.8;Fibro-adipogenic progenitors: 701.5;Fibroblasts: 381.8;Medullary thymic epithelial cells: 348.0;Mesothelial cells: 947.0;Pericytes: 598.2;Vascular smooth muscle cells: 1000.4" "Cell type enhanced" "Detected in all" "vascular associated smooth muscle cell: 1918.0" "Cancer enhanced" "Detected in all" "Thyroid Carcinoma (TCGA): 36.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "NK-cell: 1.2" "Lineage enriched" "Detected in single" 8 "NK-cells: 1.2" "Cancer enhanced" "Detected in many" "Neuroblastoma: 66.3" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Fibroblasts, Breast - Fibroblasts, Colon - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblasts_1, Minor Salivary Gland - Fibroblasts, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skin - Fibroblasts_1, Skin - Fibroblasts_2, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051630 Approved Supported "Cell Junctions" "Secreted in other tissues" "Developmental protein" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 24: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" "Cell Junctions" "HPA051630: " "unprognostic (5.43e-2)" "unprognostic (7.01e-2)" "unprognostic (1.53e-1)" "unprognostic (1.18e-1)" "unprognostic (1.08e-1)" "unprognostic (4.55e-2)" "unprognostic (2.73e-2)" "unprognostic (2.14e-1)" "unprognostic (1.22e-1)" "unprognostic (5.76e-2)" "unprognostic (4.29e-3)" "unprognostic (1.85e-3)" "unprognostic (1.04e-3)" "unprognostic (3.52e-2)" "unprognostic (4.27e-3)" "unprognostic (2.89e-3)" "unprognostic (1.52e-1)" "unprognostic (1.31e-2)" "unprognostic (8.81e-2)" "unprognostic (1.42e-2)" "unprognostic (8.89e-2)" "unprognostic (2.23e-1)" "unprognostic (5.55e-2)" "unprognostic (4.96e-1)" "unprognostic (4.24e-2)" "unprognostic (2.91e-2)" "unprognostic (2.93e-1)" "unprognostic (2.59e-3)" "unprognostic (5.80e-2)" "unprognostic (2.58e-1)" "unprognostic (3.75e-1)" SLITRK1 "KIAA1910, LRRC12" ENSG00000178235 "SLIT and NTRK like family member 1" Q96PX8 13 83877205-83882474 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 13.8" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 14.7;Brain inhibitory neurons: 10.5;Oligodendrocyte progenitor cells: 37.3;Oligodendrocytes: 29.7;Other brain neurons: 17.3;Pituicytes/FSCs: 110.6;Retinal bipolar cells: 13.0" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in single" 9 "Glioblastoma Multiforme (TCGA): 3.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 4.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074835 Enhanced "Secreted in brain" "No annotated function" NA NA 130000 "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 2 "HPA074835: " "unprognostic (2.36e-1)" "unprognostic (2.71e-1)" "potential prognostic favorable (1.34e-4)" SLITRK2 "CXorf1, CXorf2, KIAA1854, SLITL1, TMEM257" ENSG00000185985 "SLIT and NTRK like family member 2" Q9H156 X 145817829-145829856 "Predicted membrane proteins" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 11.5;retina: 30.4" "Cell type enhanced" "Detected in some" "Astrocytes: 86.0;Bergmann glia: 88.1;Brain inhibitory neurons: 32.9;Melanocytes: 53.3;Müller glia: 249.8;Oligodendrocyte progenitor cells: 132.3;Oligodendrocytes: 44.1;Schwann cells: 36.2" "Cell type enhanced" "Detected in all" "oligodendrocyte precursor cell: 151.4" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 9.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney cancer: 1.6;skin cancer: 1.6" "Adipose visceral - Mesothelial cells, Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 39000 "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 11: Muller glia cells - Retinal homeostasis" "unprognostic (2.24e-1)" "unprognostic (1.04e-2)" "potential prognostic unfavorable (1.68e-5)" "unprognostic (1.43e-1)" "unprognostic (1.13e-2)" "unprognostic (1.94e-1)" "unprognostic (4.66e-2)" SLITRK3 KIAA0848 ENSG00000121871 "SLIT and NTRK like family member 3" O94933 3 165186720-165197109 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.3;fallopian tube: 13.0" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 16.7;Brain inhibitory neurons: 19.9;Oligodendrocyte progenitor cells: 36.3;Other brain neurons: 15.0;Retinal amacrine cells: 4.8;Retinal bipolar cells: 14.3;Smooth muscle cells: 10.7" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in single" 25 "Glioblastoma Multiforme (TCGA): 12.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 10.6;prostate cancer: 2.8" "Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017636, HPA048042" Enhanced Approved Mitochondria No NA 450000 "Cluster 65: Brain - Transcription" "Cluster 29: Forebrain - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 2 Mitochondria "HPA017636: , HPA048042: " "unprognostic (1.48e-1)" "unprognostic (1.38e-1)" SLITRK4 DKFZp547M2010 ENSG00000179542 "SLIT and NTRK like family member 4" Q8IW52 X 143622790-143636101 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 9.8;brain: 9.6" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 79.4;Brain excitatory neurons: 48.5;Brain inhibitory neurons: 46.8;Leydig cells: 64.4;Oligodendrocyte progenitor cells: 36.0;Other brain neurons: 31.3;Peritubular myoid cells: 19.7;Prostatic glandular cells: 20.4;Thymic myoid cells: 32.6" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Kidney Renal Clear Cell Carcinoma (TCGA): 5.8;Kidney Renal Papillary Cell Carcinoma (TCGA): 7.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 11.7" "Group enriched" "Detected in many" 64 "dendritic cells: 3.2;granulocytes: 11.7;monocytes: 4.1" "Cancer enhanced" "Detected in some" "thyroid cancer: 2.3" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000431 Enhanced NA NA 220000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 31: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 1 "HPA000431: " "unprognostic (2.61e-1)" "unprognostic (3.49e-1)" "unprognostic (1.39e-2)" "potential prognostic favorable (1.64e-5)" "unprognostic (2.92e-2)" "unprognostic (1.02e-2)" "unprognostic (1.91e-1)" "unprognostic (2.71e-1)" "unprognostic (1.40e-1)" "unprognostic (1.38e-2)" "unprognostic (1.78e-1)" "unprognostic (1.39e-1)" "potential prognostic unfavorable (7.25e-5)" SLITRK5 "bA364G4.2, KIAA0918, LRRC11" ENSG00000165300 "SLIT and NTRK like family member 5" O94991 13 87671371-87696272 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.2;fallopian tube: 9.6;salivary gland: 9.2" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 95.9;Brain inhibitory neurons: 80.7;Ependymal cells: 31.0;Fallopian secretory cells: 22.0;Lacrimal acinar cells: 75.2;Oligodendrocyte progenitor cells: 84.0;Other brain neurons: 51.9;Pituitary stem cells: 32.5;Salivary acinar cells: 47.2;Schwann cells: 24.0" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Colon - Enteric glia cells, Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013843, HPA073230" Uncertain Approved Vesicles NA NA "Cluster 65: Brain - Transcription" "Cluster 53: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" Vesicles "HPA013843: , HPA073230: " "unprognostic (3.01e-1)" "potential prognostic favorable (2.07e-5)" "unprognostic (4.54e-1)" SLITRK6 FLJ22774 ENSG00000184564 "SLIT and NTRK like family member 6" Q9H5Y7 13 85792790-85806683 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Hearing, Sensory transduction, Vision" Deafness "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 26.2;urinary bladder: 13.8" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 37.0;Conjunctival goblet cells: 62.1;Lacrimal acinar cells: 39.9;Medullary thymic epithelial cells: 28.8;Prostatic club cells: 38.5;Prostatic hillock cells: 82.9;Respiratory basal cells: 95.2;Respiratory ciliated cells: 80.2;Respiratory deuterosomal cells: 64.3;Respiratory secretory cells: 79.2;Retinal bipolar cells: 32.2;Salivary acinar cells: 36.9;Salivary basal cells: 39.9;Submucosal glandular cells: 33.2;Urothelial cells: 32.7" "Cell type enhanced" "Detected in some" "medium spiny neuron: 19.8;thalamic excitatory: 34.0" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 21.1;Breast Invasive Carcinoma (TCGA): 36.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 40.6" "Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Thyroid gland - Fibroblasts" "Region enhanced" "Detected in many" "thalamus: 22.6" "Low region specificity" "Detected in many" "HPA014491, HPA014513" Uncertain Supported "Plasma membrane" NA NA 16000 "Cluster 60: Stomach - Digestion" "Cluster 33: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 38: Secretory epithelial cells - Exocrine secretion" "Plasma membrane" "HPA014491: , HPA014513: " "potential prognostic favorable (9.27e-4)" "unprognostic (5.92e-2)" "unprognostic (1.91e-1)" "unprognostic (1.09e-2)" "unprognostic (3.99e-1)" "unprognostic (1.08e-1)" "unprognostic (7.75e-2)" "unprognostic (1.25e-3)" "potential prognostic unfavorable (2.46e-5)" "unprognostic (1.84e-2)" "unprognostic (8.54e-2)" "unprognostic (7.53e-3)" "unprognostic (2.32e-3)" "unprognostic (1.12e-1)" "unprognostic (1.09e-1)" "unprognostic (3.45e-2)" "unprognostic (8.75e-2)" "unprognostic (4.83e-2)" "unprognostic (8.34e-3)" "unprognostic (3.74e-1)" "unprognostic (5.56e-2)" "unprognostic (1.39e-1)" "unprognostic (2.88e-2)" SLK "KIAA0204, se20-9, STK2" ENSG00000065613 "STE20 like kinase" Q9H2G2 10 103967140-104029233 "Enzymes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1015.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015757, HPA056556" Approved Approved "Plasma membrane,Cytosol" NA NA 23000 "Cluster 21: Neutrophils - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 16: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 17 Cytosol "Plasma membrane" "HPA015757: , HPA056556: " "unprognostic (1.48e-2)" "unprognostic (2.70e-2)" "unprognostic (2.43e-1)" "unprognostic (1.16e-2)" "unprognostic (2.45e-1)" "unprognostic (2.90e-1)" "unprognostic (1.23e-1)" "unprognostic (1.16e-2)" "unprognostic (2.42e-1)" "unprognostic (1.15e-1)" "validated prognostic favorable (1.83e-7)" "validated prognostic favorable (6.34e-5)" "unprognostic (3.46e-2)" "unprognostic (1.12e-1)" "unprognostic (1.10e-1)" "unprognostic (1.04e-2)" "unprognostic (5.24e-2)" "unprognostic (2.12e-1)" "unprognostic (2.75e-1)" "unprognostic (8.65e-2)" "unprognostic (3.48e-2)" "potential prognostic unfavorable (1.11e-4)" "unprognostic (2.97e-2)" "unprognostic (7.81e-2)" "unprognostic (5.13e-2)" "unprognostic (2.40e-2)" "unprognostic (2.09e-1)" "unprognostic (2.05e-1)" "unprognostic (4.75e-1)" "unprognostic (6.83e-3)" "unprognostic (4.16e-1)" SLMAP "KIAA1601, SLAP" ENSG00000163681 "Sarcolemma associated protein" Q14BN4 3 57755450-57930003 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 772.2;Smooth muscle cells: 909.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal cortex cells, Breast - Breast myoepithelial cells, Colon - Smooth muscle cells, Prostate - Smooth muscle cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002357, HPA002358" Enhanced Approved "Endoplasmic reticulum" NA NA 3800 "Cluster 35: Neutrophils - Protein binding" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 15: Non-specific - Transcription" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 62: Smooth muscle cells - Muscle contraction" 49 "Endoplasmic reticulum" "HPA002357: , HPA002358: " "unprognostic (1.32e-2)" "unprognostic (1.85e-1)" "unprognostic (2.19e-2)" "unprognostic (1.02e-1)" "unprognostic (1.26e-1)" "unprognostic (3.69e-2)" "unprognostic (1.83e-1)" "unprognostic (1.64e-1)" "unprognostic (2.52e-2)" "unprognostic (3.90e-2)" "validated prognostic favorable (5.62e-7)" "validated prognostic favorable (8.92e-5)" "unprognostic (3.59e-2)" "unprognostic (1.27e-1)" "unprognostic (1.34e-2)" "unprognostic (5.87e-2)" "unprognostic (8.92e-3)" "unprognostic (6.16e-2)" "unprognostic (9.35e-2)" "unprognostic (4.01e-2)" "unprognostic (5.20e-2)" "unprognostic (2.03e-3)" "unprognostic (5.00e-2)" "unprognostic (1.08e-1)" "unprognostic (2.93e-2)" "unprognostic (1.69e-2)" "unprognostic (6.14e-2)" "unprognostic (4.41e-2)" "unprognostic (5.66e-1)" "unprognostic (1.19e-2)" "unprognostic (2.09e-1)" SLN "MGC12301, MGC125854, MGC125855" ENSG00000170290 Sarcolipin O00631 11 107707378-107719693 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "skeletal muscle: 7680.1;tongue: 3171.0" "Group enriched" "Detected in some" 17 "Müller glia: 306.2;Myonuclei: 129.3;Thymic myoid cells: 348.1" "Cell type enriched" "Detected in some" 6 "cerebellar inhibitory: 25.4" "Group enriched" "Detected in many" 6 "Glioblastoma Multiforme (TCGA): 54.3;Head and Neck Squamous Cell Carcinoma (TCGA): 50.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 35 "Rhabdoid: 202.2" "Adipose visceral - Smooth muscle cells, Adrenal gland - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Skin - Inner root sheath cells" CAB011628 Approved Microtubules NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 5: Rhabdoid - Unknown function" "Cluster 11: Muller glia cells - Retinal homeostasis" 6 Microtubules "CAB011628: " "unprognostic (2.28e-1)" "unprognostic (3.78e-2)" "unprognostic (9.87e-3)" "unprognostic (1.65e-1)" "unprognostic (6.09e-3)" "unprognostic (3.48e-1)" "unprognostic (4.28e-3)" "potential prognostic unfavorable (8.44e-7)" "unprognostic (1.47e-3)" "unprognostic (2.97e-1)" "unprognostic (2.58e-2)" "unprognostic (2.29e-1)" "unprognostic (2.57e-1)" "unprognostic (3.73e-3)" SLPI "ALK1, ALP, BLPI, HUSI, HUSI-I, WAP4, WFDC4" ENSG00000124107 "Secretory leukocyte peptidase inhibitor" P03973 20 45252239-45254564 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Antibiotic, Antimicrobial, Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "cervix: 26260.0;salivary gland: 14071.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 7287.2;Conjunctival goblet cells: 12808.6;Endometrial secretory cells: 16781.7;Esophageal apical cells: 20421.8;Lacrimal acinar cells: 10826.4;Respiratory deuterosomal cells: 12518.3;Respiratory secretory cells: 25615.0;Salivary acinar cells: 11099.1;Salivary duct cells: 7577.7;Submucosal glandular cells: 31818.4;Transitional alveolar cells: 11204.8" "Group enriched" "Detected in some" 5 "endothelial cell: 10.0;fibroblast: 38.4" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 7 "choroid plexus: 50.1;thalamus: 14.3" "Immune cell enriched" "Detected in some" 80 "neutrophil: 323.6" "Lineage enriched" "Detected in many" 80 "granulocytes: 323.6" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 652.3" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB002303, HPA027774" Enhanced Approved "Golgi apparatus" "Secreted to blood" Immunity NA NA 26400000 20000000 "Cluster 4: Neutrophils - Degranulation" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 15: Kidney cancer - Membrane components" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 13 "Golgi apparatus" "CAB002303: , HPA027774: " "unprognostic (2.48e-1)" "unprognostic (5.30e-2)" "unprognostic (1.13e-1)" "unprognostic (4.37e-1)" "unprognostic (2.05e-1)" "unprognostic (4.64e-2)" "unprognostic (3.30e-2)" "potential prognostic unfavorable (9.64e-4)" "unprognostic (4.20e-2)" "unprognostic (3.67e-1)" "potential prognostic unfavorable (4.04e-9)" "unprognostic (7.35e-2)" "unprognostic (9.86e-2)" "unprognostic (1.32e-1)" "unprognostic (1.09e-2)" "unprognostic (2.65e-1)" "unprognostic (1.35e-1)" "unprognostic (1.21e-1)" "unprognostic (5.16e-3)" "validated prognostic unfavorable (1.99e-4)" "validated prognostic unfavorable (1.46e-4)" "unprognostic (2.17e-2)" "unprognostic (9.43e-2)" "unprognostic (1.29e-2)" "unprognostic (1.06e-1)" "unprognostic (2.74e-2)" "unprognostic (2.42e-1)" "unprognostic (1.81e-1)" "unprognostic (1.87e-1)" "unprognostic (7.72e-2)" "unprognostic (1.16e-1)" SLTM "FLJ13213, Met" ENSG00000137776 "SAFB like transcription modulator" Q9NWH9 15 58879050-58933679 "Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040256, HPA040381" Enhanced Enhanced "Nucleoplasm,Nuclear bodies" NA NA 20000 "Cluster 22: Eosinophils - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 28 "Nucleoplasm, Nuclear bodies" "HPA040256: , HPA040381: " "unprognostic (2.12e-1)" "unprognostic (9.55e-2)" "unprognostic (4.93e-2)" "unprognostic (3.70e-2)" "unprognostic (6.98e-2)" "unprognostic (3.03e-2)" "unprognostic (3.65e-2)" "unprognostic (2.39e-1)" "unprognostic (1.86e-1)" "unprognostic (5.46e-2)" "validated prognostic favorable (2.69e-5)" "validated prognostic favorable (4.09e-5)" "unprognostic (8.89e-2)" "unprognostic (6.52e-2)" "unprognostic (2.48e-1)" "unprognostic (6.92e-2)" "unprognostic (1.75e-1)" "unprognostic (1.03e-1)" "unprognostic (1.79e-2)" "unprognostic (9.84e-2)" "unprognostic (2.68e-1)" "unprognostic (3.57e-1)" "unprognostic (6.57e-3)" "unprognostic (7.75e-2)" "unprognostic (5.62e-2)" "unprognostic (3.23e-2)" "unprognostic (3.23e-1)" "unprognostic (1.07e-1)" "unprognostic (2.41e-1)" "unprognostic (8.91e-2)" "unprognostic (3.56e-2)" SLU7 9G8 ENSG00000164609 "SLU7 homolog, splicing factor" O95391 5 160401641-160421711 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 196.7;Neutrophils: 193.5;Oocytes: 207.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035907, HPA058120" Uncertain Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 34: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 17: Non-specific - RNA processing" 34 Nucleoplasm "Nuclear speckles" "HPA035907: , HPA058120: " "unprognostic (4.38e-2)" "unprognostic (6.81e-2)" "unprognostic (3.05e-2)" "unprognostic (3.70e-1)" "unprognostic (1.20e-1)" "unprognostic (1.24e-1)" "unprognostic (1.34e-1)" "unprognostic (1.38e-1)" "unprognostic (2.35e-1)" "unprognostic (9.43e-2)" "potential prognostic favorable (3.18e-9)" "unprognostic (2.21e-3)" "unprognostic (2.90e-1)" "potential prognostic unfavorable (2.78e-4)" "unprognostic (8.80e-2)" "unprognostic (3.65e-2)" "unprognostic (3.82e-1)" "unprognostic (1.44e-2)" "unprognostic (3.11e-1)" "unprognostic (4.18e-2)" "potential prognostic unfavorable (5.38e-4)" "unprognostic (1.26e-1)" "potential prognostic unfavorable (1.62e-4)" "unprognostic (1.08e-1)" "unprognostic (4.68e-2)" "unprognostic (3.22e-1)" "unprognostic (1.06e-1)" "unprognostic (3.08e-1)" "unprognostic (1.61e-1)" "unprognostic (1.99e-1)" "unprognostic (1.66e-1)" SLURP1 "ANUP, ARS, ArsB, LY6-MT, LY6LS, MDM" ENSG00000126233 "Secreted LY6/PLAUR domain containing 1" P55000 8 142740949-142742406 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" Cytokine "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 1037.0;skin 1: 854.7" "Cell type enriched" "Detected in some" 10 "Esophageal apical cells: 29388.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 128.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "breast cancer: 1.8;Esophageal cancer: 1.7;head and neck cancer: 2.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA050967 Approved "Secreted in other tissues" Cytokine NA NA 2100000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 37: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 60 "HPA050967: " "unprognostic (3.12e-1)" "unprognostic (6.31e-3)" "unprognostic (6.29e-1)" "unprognostic (1.83e-1)" "unprognostic (2.14e-2)" "unprognostic (1.55e-1)" "unprognostic (1.80e-2)" "unprognostic (2.12e-1)" "potential prognostic unfavorable (1.89e-4)" "unprognostic (1.32e-1)" "unprognostic (1.61e-1)" "unprognostic (5.34e-1)" SLURP2 ENSG00000283992 "Secreted LY6/PLAUR domain containing 2" P0DP57 8 142764338-142769828 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 196.5;esophagus: 866.6;skin 1: 332.1;vagina: 216.7" "Cell type enriched" "Detected in some" 6 "Esophageal apical cells: 39.4" "Cell type enhanced" "Detected in some" "vascular associated smooth muscle cell: 5.5" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 271.3;Head and Neck Squamous Cell Carcinoma (TCGA): 357.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Esophageal cancer: 4.2;head and neck cancer: 12.8" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Prostate - Smooth muscle cells" "Secreted in other tissues" "No annotated function" NA NA 820000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 37: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" "unprognostic (3.23e-1)" "unprognostic (1.08e-1)" "unprognostic (3.57e-3)" "unprognostic (5.42e-3)" "unprognostic (2.38e-2)" "unprognostic (4.89e-2)" "unprognostic (4.65e-3)" "unprognostic (1.27e-2)" "potential prognostic unfavorable (4.78e-5)" "unprognostic (6.40e-2)" "unprognostic (2.36e-1)" "unprognostic (3.41e-1)" "unprognostic (1.71e-2)" "unprognostic (7.80e-2)" SLX1A GIYD1 ENSG00000132207 "SLX1 homolog A, structure-specific endonuclease subunit" Q9BQ83 16 30193875-30197561 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 5.9;Bergmann glia: 4.7;Brain excitatory neurons: 3.4;Brain inhibitory neurons: 2.7;Choroid plexus epithelial cells: 1.5;Ependymal cells: 2.2;Microglia: 7.1;Oligodendrocyte progenitor cells: 6.0;Oligodendrocytes: 8.1;Other brain neurons: 3.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA047038 Uncertain Supported Nucleoplasm NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 54: Non-specific - Transcription" "Cluster 22: Non-specific - Basic cellular functions" 7 Nucleoplasm "HPA047038: " "unprognostic (1.53e-2)" "unprognostic (4.75e-2)" "unprognostic (3.54e-3)" "unprognostic (1.66e-2)" "unprognostic (4.52e-3)" "unprognostic (2.27e-1)" "unprognostic (2.45e-1)" "unprognostic (2.06e-2)" "unprognostic (5.43e-3)" "unprognostic (1.51e-2)" "unprognostic (8.02e-3)" "unprognostic (2.47e-1)" "unprognostic (1.39e-1)" "unprognostic (7.95e-3)" "unprognostic (1.11e-1)" "unprognostic (7.46e-2)" "unprognostic (2.55e-1)" "unprognostic (9.27e-2)" "unprognostic (2.71e-3)" "unprognostic (2.17e-2)" "unprognostic (3.52e-2)" "unprognostic (1.78e-1)" "unprognostic (1.35e-1)" "unprognostic (3.75e-1)" "unprognostic (6.61e-2)" "unprognostic (8.80e-2)" "unprognostic (1.16e-1)" "unprognostic (4.28e-2)" "unprognostic (1.98e-1)" SLX1B "GIYD2, MGC5178" ENSG00000181625 "SLX1 homolog B, structure-specific endonuclease subunit" Q9BQ83 16 29454533-29458219 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 42.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA047038 Uncertain Supported Nucleoplasm NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 6: Non-specific - Immune response" "Cluster 54: Non-specific - Transcription" "Cluster 102: Non-specific - Mixed function" 5 Nucleoplasm "HPA047038: " "unprognostic (6.45e-3)" "unprognostic (7.36e-3)" "potential prognostic favorable (4.27e-5)" "unprognostic (1.57e-1)" "unprognostic (1.90e-1)" "unprognostic (9.34e-3)" "unprognostic (7.54e-3)" "unprognostic (3.55e-1)" "unprognostic (1.82e-1)" "unprognostic (3.46e-2)" "unprognostic (1.25e-1)" "unprognostic (1.68e-1)" "unprognostic (1.07e-2)" "unprognostic (1.39e-1)" "unprognostic (4.97e-2)" "unprognostic (1.13e-1)" "unprognostic (7.16e-3)" "unprognostic (1.95e-1)" "unprognostic (3.04e-1)" "unprognostic (9.79e-2)" "unprognostic (1.40e-3)" "unprognostic (5.04e-1)" "unprognostic (9.93e-2)" "unprognostic (9.05e-2)" "unprognostic (9.36e-2)" "unprognostic (2.39e-1)" "unprognostic (1.22e-1)" "unprognostic (1.96e-1)" "unprognostic (6.18e-2)" "unprognostic (2.07e-1)" SLX4 "BTBD12, FANCP, KIAA1784, KIAA1987" ENSG00000188827 "SLX4 structure-specific endonuclease subunit" Q8IY92 16 3581181-3611606 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" "Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 13.5;testis: 10.0" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 25.2;Platelets: 74.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066238, HPA073951" Approved Supported Nucleoplasm NA NA "Cluster 67: Testis - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 47: Platelets - Hemostasis" 100 Nucleoplasm "HPA066238: , HPA073951: " "unprognostic (5.55e-2)" "unprognostic (3.00e-2)" "unprognostic (2.84e-3)" "unprognostic (4.12e-2)" "unprognostic (8.29e-2)" "unprognostic (3.04e-1)" "unprognostic (6.36e-2)" "unprognostic (2.65e-3)" "unprognostic (4.99e-2)" "unprognostic (4.58e-3)" "unprognostic (4.97e-2)" "unprognostic (3.40e-1)" "potential prognostic unfavorable (6.21e-6)" "unprognostic (7.68e-2)" "unprognostic (1.24e-1)" "unprognostic (5.34e-2)" "unprognostic (8.38e-2)" "unprognostic (1.01e-3)" "unprognostic (1.02e-1)" "unprognostic (3.74e-1)" "unprognostic (4.59e-2)" "unprognostic (1.75e-3)" "unprognostic (3.20e-1)" "unprognostic (9.68e-3)" "unprognostic (1.50e-2)" "unprognostic (2.46e-1)" "unprognostic (3.97e-3)" "unprognostic (4.89e-1)" "unprognostic (1.80e-3)" "unprognostic (9.85e-2)" SLX4IP "C20orf94, dJ1099D15.3" ENSG00000149346 "SLX4 interacting protein" Q5VYV7 20 10435305-10636829 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Somatotrophs: 268.5;Thyrotrophs: 252.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046372 Approved Approved Cytosol NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 22: Epididymis - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 62: Non-specific - Plasma proteins" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 9 Cytosol "HPA046372: " "unprognostic (1.84e-1)" "unprognostic (2.20e-3)" "unprognostic (5.96e-2)" "unprognostic (7.04e-2)" "unprognostic (2.63e-2)" "unprognostic (3.11e-1)" "unprognostic (1.30e-1)" "unprognostic (3.45e-2)" "unprognostic (5.19e-2)" "unprognostic (4.61e-1)" "unprognostic (1.35e-1)" "unprognostic (2.01e-1)" "potential prognostic unfavorable (1.04e-4)" "unprognostic (2.19e-1)" "unprognostic (1.51e-1)" "unprognostic (2.30e-2)" "unprognostic (2.30e-1)" "unprognostic (1.72e-1)" "unprognostic (1.16e-1)" "unprognostic (1.70e-2)" "unprognostic (3.42e-2)" "unprognostic (2.35e-1)" "unprognostic (4.54e-2)" "unprognostic (1.03e-1)" "unprognostic (2.65e-1)" "unprognostic (4.40e-2)" "unprognostic (2.87e-1)" "potential prognostic unfavorable (4.20e-4)" "unprognostic (3.06e-2)" SLX9 "C21orf70, FAM207A, PRED56" ENSG00000160256 "SLX9 ribosome biogenesis factor" Q9NSI2 21 44940012-44976989 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 175.0;Thymic myoid cells: 144.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034178, HPA036354, HPA036559" Approved Supported Nucleoplasm,Nucleoli NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 97: Non-specific - Cellular respiration" 40 Nucleoli Nucleoplasm "CAB034178: , HPA036354: , HPA036559: " "potential prognostic unfavorable (4.32e-4)" "unprognostic (1.94e-1)" "unprognostic (2.96e-1)" "unprognostic (1.37e-1)" "unprognostic (3.45e-2)" "unprognostic (5.38e-2)" "unprognostic (1.17e-2)" "unprognostic (7.45e-3)" "unprognostic (2.91e-1)" "unprognostic (1.50e-2)" "unprognostic (3.39e-3)" "unprognostic (6.46e-2)" "potential prognostic unfavorable (1.46e-4)" "potential prognostic unfavorable (3.09e-5)" "unprognostic (2.00e-2)" "unprognostic (1.59e-1)" "unprognostic (8.60e-2)" "unprognostic (1.53e-3)" "unprognostic (3.69e-2)" "unprognostic (1.94e-2)" "unprognostic (8.56e-2)" "unprognostic (8.03e-2)" "unprognostic (3.20e-1)" "unprognostic (9.58e-2)" "unprognostic (3.16e-2)" "unprognostic (1.99e-1)" "unprognostic (1.43e-1)" "unprognostic (1.37e-1)" "unprognostic (3.54e-3)" SMAD1 "JV4-1, MADH1, MADR1" ENSG00000170365 "SMAD family member 1" Q15797 4 145481194-145559176 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 304.3;Lymphatic endothelial cells: 528.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 46.5;non-classical monocyte: 22.3" "Group enriched" "Detected in many" 5 "granulocytes: 46.5;monocytes: 22.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005389 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 61 "Nucleoplasm, Cytosol" "CAB005389: " "unprognostic (2.40e-2)" "unprognostic (1.29e-1)" "unprognostic (5.56e-2)" "unprognostic (1.25e-1)" "unprognostic (1.04e-1)" "unprognostic (3.20e-1)" "unprognostic (3.87e-1)" "unprognostic (1.98e-1)" "unprognostic (8.38e-2)" "unprognostic (6.95e-3)" "unprognostic (3.27e-3)" "unprognostic (3.40e-2)" "unprognostic (5.75e-2)" "unprognostic (8.67e-2)" "unprognostic (3.00e-3)" "unprognostic (1.94e-2)" "unprognostic (6.47e-3)" "unprognostic (1.74e-1)" "unprognostic (3.10e-1)" "potential prognostic unfavorable (7.25e-5)" "unprognostic (7.26e-2)" "unprognostic (2.01e-1)" "unprognostic (3.77e-2)" "unprognostic (1.44e-1)" "unprognostic (2.95e-2)" "unprognostic (1.17e-1)" "unprognostic (5.19e-2)" "unprognostic (3.60e-1)" "unprognostic (8.84e-2)" "unprognostic (1.08e-3)" "unprognostic (3.11e-1)" SMAD2 "JV18-1, MADH2, MADR2" ENSG00000175387 "SMAD family member 2" Q15796 18 47808957-47931146 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant, Heterotaxy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Endothelial cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025507, HPA067203, CAB073546" Approved Supported "Nucleoplasm,Nucleoli,Vesicles,Primary cilium transition zone,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 7: Non-specific - Transcription" 109 "Nucleoplasm, Nucleoli" "Vesicles, Primary cilium transition zone, Cytosol" "CAB025507: , CAB073546: , HPA067203: " "unprognostic (9.69e-3)" "unprognostic (5.71e-2)" "unprognostic (7.85e-2)" "unprognostic (2.17e-2)" "unprognostic (5.87e-2)" "unprognostic (2.31e-2)" "unprognostic (1.49e-1)" "unprognostic (2.72e-2)" "unprognostic (2.01e-1)" "potential prognostic unfavorable (9.99e-4)" "potential prognostic favorable (6.97e-8)" "unprognostic (1.13e-3)" "unprognostic (2.14e-1)" "validated prognostic unfavorable (1.28e-4)" "validated prognostic unfavorable (2.25e-4)" "unprognostic (6.03e-3)" "unprognostic (1.76e-2)" "unprognostic (9.65e-2)" "unprognostic (1.84e-2)" "unprognostic (3.71e-2)" "unprognostic (2.24e-2)" "unprognostic (1.71e-3)" "unprognostic (1.00e-1)" "unprognostic (1.24e-1)" "unprognostic (1.17e-1)" "unprognostic (1.05e-1)" "unprognostic (1.43e-2)" "unprognostic (1.01e-1)" "unprognostic (3.38e-1)" "unprognostic (2.33e-2)" "unprognostic (4.99e-2)" SMAD3 "HsT17436, JV15-2, MADH3" ENSG00000166949 "SMAD family member 3" P84022 15 67063763-67195173 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" DNA-binding "Aortic aneurysm, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 778.2;Myonuclei: 586.8;Ocular epithelial cells: 585.8;Urothelial cells: 1009.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008094, HPA046386, HPA067203, CAB069409" Approved Supported "Nucleoplasm,Vesicles,Primary cilium transition zone,Basal body" NA Yes "Cluster 3: Non-specific - Nuclear processes" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 51: Secretory epithelial cells - Mixed function" 210 Nucleoplasm "Vesicles, Primary cilium transition zone, Basal body" "CAB008094: , CAB069409: , HPA046386: , HPA067203: " "unprognostic (6.56e-2)" "unprognostic (1.48e-1)" "unprognostic (8.19e-2)" "unprognostic (1.27e-2)" "unprognostic (2.97e-2)" "unprognostic (5.19e-2)" "unprognostic (2.34e-1)" "unprognostic (9.28e-2)" "unprognostic (1.65e-2)" "unprognostic (6.35e-3)" "potential prognostic favorable (1.36e-4)" "unprognostic (9.12e-3)" "unprognostic (9.36e-3)" "unprognostic (7.16e-3)" "unprognostic (2.41e-2)" "validated prognostic unfavorable (2.27e-4)" "validated prognostic unfavorable (4.50e-4)" "unprognostic (1.88e-1)" "unprognostic (1.14e-1)" "unprognostic (3.78e-2)" "unprognostic (1.95e-1)" "potential prognostic unfavorable (2.38e-4)" "unprognostic (1.27e-1)" "unprognostic (1.31e-1)" "unprognostic (4.90e-2)" "potential prognostic favorable (1.23e-4)" "unprognostic (4.12e-2)" "unprognostic (3.17e-1)" "unprognostic (3.42e-1)" "unprognostic (4.24e-1)" "unprognostic (2.81e-2)" SMAD4 "DPC4, MADH4" ENSG00000141646 "SMAD family member 4" Q13485 18 51028394-51085045 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019154, CAB080136" Approved Supported "Nucleoplasm,Vesicles,Primary cilium tip,Centrosome,Basal body,Cytosol" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 15: Non-specific - Transcription" "Cluster 13: Non-specific - Mixed function" "Cluster 22: Non-specific - Basic cellular functions" 183 "Nucleoplasm, Centrosome, Basal body" "Vesicles, Primary cilium tip, Cytosol" "CAB080136: , HPA019154: " "unprognostic (2.13e-3)" "unprognostic (2.64e-1)" "unprognostic (3.40e-2)" "unprognostic (3.26e-2)" "unprognostic (2.14e-1)" "unprognostic (2.05e-1)" "unprognostic (5.94e-2)" "unprognostic (5.31e-3)" "unprognostic (1.29e-1)" "unprognostic (1.16e-2)" "validated prognostic favorable (6.82e-5)" "validated prognostic favorable (9.35e-5)" "unprognostic (2.62e-3)" "unprognostic (1.15e-2)" "unprognostic (1.94e-1)" "unprognostic (1.21e-1)" "unprognostic (9.51e-2)" "unprognostic (3.96e-1)" "unprognostic (1.56e-2)" "unprognostic (4.76e-1)" "unprognostic (2.29e-1)" "unprognostic (6.76e-3)" "unprognostic (2.16e-1)" "unprognostic (1.70e-1)" "unprognostic (2.41e-1)" "unprognostic (2.42e-1)" "unprognostic (5.54e-2)" "unprognostic (1.51e-1)" "unprognostic (1.74e-1)" "unprognostic (3.79e-2)" "unprognostic (4.05e-1)" SMAD5 "Dwfc, JV5-1, MADH5" ENSG00000113658 "SMAD family member 5" Q99717 5 136132845-136188747 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 92.2" "Lineage enriched" "Detected in all" 4 "granulocytes: 92.2" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058931 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 32: Basophils - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 17: Non-specific - RNA processing" 16 Nucleoplasm Cytosol "HPA058931: " "unprognostic (2.26e-2)" "unprognostic (2.58e-2)" "unprognostic (9.27e-2)" "unprognostic (7.42e-2)" "unprognostic (2.97e-1)" "unprognostic (2.17e-2)" "unprognostic (2.39e-1)" "unprognostic (1.13e-1)" "unprognostic (1.23e-1)" "potential prognostic unfavorable (3.55e-6)" "validated prognostic favorable (2.76e-5)" "validated prognostic favorable (2.34e-4)" "unprognostic (1.06e-1)" "unprognostic (7.56e-2)" "unprognostic (2.51e-1)" "unprognostic (4.37e-1)" "unprognostic (3.22e-2)" "unprognostic (8.79e-2)" "unprognostic (7.58e-2)" "unprognostic (3.18e-2)" "unprognostic (5.36e-3)" "unprognostic (1.47e-1)" "unprognostic (8.97e-2)" "unprognostic (7.54e-2)" "unprognostic (3.39e-2)" "unprognostic (1.70e-1)" "unprognostic (7.84e-2)" "unprognostic (1.59e-2)" "unprognostic (4.01e-1)" "unprognostic (3.93e-2)" "unprognostic (9.14e-2)" SMAD6 "HsT17432, MADH6, MADH7" ENSG00000137834 "SMAD family member 6" O43541 15 66702236-66782849 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 28.9;lung: 26.3" "Cell type enhanced" "Detected in many" "Adipocytes: 126.6;Choroid plexus epithelial cells: 51.5;Pituitary stem cells: 58.5;Podocytes: 219.1;Vascular endothelial cells: 147.5" "Cell type enriched" "Detected in some" 4 "endothelial cell: 273.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA061917 Supported "Nucleoplasm,Nuclear bodies,Golgi apparatus,Primary cilium,Basal body,Cytosol" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 15: Kidney cancer - Membrane components" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 19 "Nucleoplasm, Nuclear bodies" "Golgi apparatus, Primary cilium, Basal body, Cytosol" "HPA061917: " "unprognostic (1.59e-2)" "unprognostic (2.12e-1)" "unprognostic (1.69e-1)" "unprognostic (1.75e-2)" "unprognostic (9.55e-3)" "unprognostic (7.05e-2)" "unprognostic (2.10e-1)" "unprognostic (5.59e-3)" "unprognostic (2.97e-2)" "unprognostic (1.65e-1)" "validated prognostic favorable (4.14e-8)" "validated prognostic favorable (4.41e-4)" "unprognostic (6.30e-2)" "unprognostic (4.91e-2)" "unprognostic (1.52e-1)" "unprognostic (3.77e-2)" "unprognostic (2.87e-2)" "unprognostic (2.19e-2)" "unprognostic (2.22e-2)" "unprognostic (4.40e-1)" "unprognostic (1.31e-1)" "unprognostic (2.41e-3)" "unprognostic (8.42e-3)" "unprognostic (2.19e-1)" "unprognostic (2.17e-1)" "unprognostic (5.28e-2)" "unprognostic (2.49e-1)" "unprognostic (1.54e-2)" "unprognostic (4.50e-2)" "unprognostic (1.15e-1)" "unprognostic (5.70e-2)" SMAD7 "MADH7, MADH8" ENSG00000101665 "SMAD family member 7" O15105 18 48919853-48950965 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 49.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 115.2;Endometrial glandular cells: 64.5;Endometrial luminal cells: 81.7;Vascular endothelial cells: 64.2" "Cell type enhanced" "Detected in all" "endothelial cell: 88.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 4.5;eosinophil: 5.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Prostate - Fibroblasts, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026212, HPA028897" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Centrosome,Basal body,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 25: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 58 "Nucleoplasm, Centrosome, Basal body" "Nucleoli fibrillar center, Cytosol" "CAB026212: , HPA028897: " "unprognostic (1.25e-1)" "unprognostic (1.56e-1)" "unprognostic (1.18e-1)" "potential prognostic unfavorable (1.76e-4)" "unprognostic (1.94e-1)" "unprognostic (2.17e-1)" "unprognostic (2.71e-1)" "unprognostic (9.22e-2)" "unprognostic (3.46e-1)" "unprognostic (9.39e-2)" "potential prognostic favorable (3.24e-5)" "unprognostic (9.98e-3)" "unprognostic (9.85e-3)" "unprognostic (1.18e-1)" "unprognostic (9.74e-2)" "unprognostic (5.66e-3)" "unprognostic (6.20e-2)" "potential prognostic unfavorable (1.58e-4)" "unprognostic (2.79e-1)" "unprognostic (4.40e-2)" "unprognostic (1.33e-1)" "unprognostic (2.00e-1)" "unprognostic (9.55e-2)" "unprognostic (2.97e-1)" "unprognostic (3.11e-2)" "unprognostic (1.53e-1)" "unprognostic (3.85e-1)" "unprognostic (2.05e-1)" "unprognostic (9.09e-2)" "unprognostic (8.85e-3)" "unprognostic (5.63e-2)" SMAD9 "MADH6, MADH9, SMAD8, SMAD8/9" ENSG00000120693 "SMAD family member 9" O15198 13 36844831-36920765 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 36.2" "Cell type enhanced" "Detected in many" "Bergmann glia: 206.5;Endometrial glandular cells: 146.3;Lymphatic endothelial cells: 91.1;Pituitary stem cells: 196.7;Thymic myoid cells: 270.6;Thyrotrophs: 134.6;Undifferentiated spermatogonia: 92.0;Vascular endothelial cells: 93.9" "Group enriched" "Detected in all" 4 "astrocyte: 86.3;Bergmann glia: 246.9;endothelial cell: 250.9;hippocampal dentate gyrus: 82.5;midbrain-derived inhibitory: 190.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 41.1" "Minor Salivary Gland - Minor salivary glandular cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "CAB009119, HPA031162" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 38: Non-specific - Basic cellular processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 15 Nucleoplasm Cytosol "CAB009119: , HPA031162: " "unprognostic (4.80e-3)" "unprognostic (1.36e-1)" "unprognostic (3.83e-1)" "unprognostic (5.53e-3)" "unprognostic (1.01e-2)" "unprognostic (2.54e-1)" "unprognostic (1.07e-2)" "potential prognostic favorable (2.08e-4)" "unprognostic (9.22e-2)" "potential prognostic favorable (7.48e-4)" "unprognostic (2.75e-2)" "unprognostic (1.24e-2)" "unprognostic (8.49e-2)" "potential prognostic favorable (2.36e-4)" "unprognostic (1.25e-2)" "unprognostic (9.85e-2)" "unprognostic (1.18e-1)" "unprognostic (7.51e-3)" "unprognostic (7.65e-3)" "unprognostic (1.58e-2)" "unprognostic (6.37e-2)" "unprognostic (1.84e-1)" "unprognostic (4.23e-2)" "unprognostic (2.58e-2)" "unprognostic (9.72e-2)" "potential prognostic unfavorable (3.57e-5)" "unprognostic (3.72e-2)" SMAGP "hSMAGP, MGC149453, MGC149454" ENSG00000170545 "Small cell adhesion glycoprotein" Q0VAQ4 12 51244558-51270415 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 136.4;placenta: 96.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1624.2;Esophageal apical cells: 1505.9;Esophageal suprabasal cells: 403.7;Migrating cytotrophoblasts: 561.4;Syncytiotrophoblasts: 901.2" "Cell type enhanced" "Detected in many" "endothelial cell: 15.1;fibroblast: 11.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Heart muscle - Endothelial cells, Skeletal muscle - Endothelial cells, Thyroid gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039711 Enhanced Supported "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 35 "Plasma membrane" "Nucleoplasm, Cell Junctions" "HPA039711: " "unprognostic (1.38e-1)" "unprognostic (5.49e-3)" "unprognostic (2.98e-2)" "unprognostic (1.15e-1)" "unprognostic (7.82e-2)" "unprognostic (6.51e-3)" "unprognostic (1.98e-3)" "potential prognostic unfavorable (7.00e-4)" "unprognostic (1.03e-1)" "unprognostic (4.27e-2)" "potential prognostic favorable (8.89e-6)" "unprognostic (3.39e-1)" "potential prognostic favorable (3.15e-4)" "unprognostic (2.66e-3)" "unprognostic (7.31e-3)" "unprognostic (1.44e-2)" "unprognostic (7.54e-3)" "unprognostic (4.39e-2)" "unprognostic (9.60e-2)" "unprognostic (4.82e-2)" "unprognostic (6.07e-2)" "potential prognostic unfavorable (6.27e-5)" "unprognostic (3.33e-2)" "unprognostic (1.61e-1)" "unprognostic (1.88e-2)" "unprognostic (2.17e-2)" "unprognostic (9.72e-2)" "unprognostic (4.40e-3)" "unprognostic (2.17e-1)" "unprognostic (1.76e-2)" "unprognostic (1.79e-1)" SMAP1 "FLJ13159, SMAP-1" ENSG00000112305 "Small ArfGAP 1" Q8IYB5 6 70667776-70862011 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 496.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030574 Approved Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 14: Neurons - Synaptic function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 2 "Plasma membrane, Cytosol" "Golgi apparatus" "HPA030574: " "unprognostic (8.81e-2)" "unprognostic (7.88e-3)" "unprognostic (2.71e-2)" "unprognostic (3.17e-2)" "potential prognostic favorable (6.87e-4)" "unprognostic (2.64e-2)" "unprognostic (5.01e-2)" "unprognostic (2.07e-2)" "unprognostic (1.55e-2)" "unprognostic (1.67e-2)" "potential prognostic favorable (1.87e-5)" "unprognostic (4.23e-2)" "unprognostic (2.22e-1)" "validated prognostic unfavorable (9.45e-6)" "validated prognostic unfavorable (8.40e-5)" "unprognostic (7.00e-2)" "unprognostic (1.91e-2)" "unprognostic (2.92e-1)" "unprognostic (1.31e-1)" "unprognostic (2.15e-1)" "unprognostic (4.27e-2)" "unprognostic (6.95e-2)" "unprognostic (3.04e-1)" "unprognostic (1.74e-1)" "unprognostic (7.07e-2)" "unprognostic (2.06e-1)" "unprognostic (8.39e-2)" "unprognostic (2.43e-1)" "unprognostic (7.06e-2)" "unprognostic (1.00e-1)" "unprognostic (1.71e-1)" SMAP2 SMAP1L ENSG00000084070 "Small ArfGAP2" Q8WU79 1 40344850-40423326 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 208.2" "Cell type enriched" "Detected in many" 4 "Neutrophils: 4946.2" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 751.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adrenal gland - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Lung - Neutrophils_2, Prostate - Macrophages, Skin - Keratinocyte (granular), Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021466, HPA024424" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 14: Neurons - Synaptic function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 15 Cytosol Nucleoplasm "HPA021466: , HPA024424: " "unprognostic (2.39e-3)" "unprognostic (1.31e-1)" "unprognostic (6.22e-2)" "unprognostic (1.10e-2)" "unprognostic (1.15e-1)" "unprognostic (2.07e-1)" "unprognostic (1.68e-1)" "unprognostic (1.26e-3)" "potential prognostic favorable (2.99e-4)" "unprognostic (4.51e-3)" "potential prognostic favorable (5.15e-4)" "unprognostic (3.80e-2)" "unprognostic (1.95e-1)" "potential prognostic unfavorable (4.30e-4)" "unprognostic (1.85e-2)" "unprognostic (2.87e-2)" "unprognostic (2.18e-1)" "unprognostic (1.50e-2)" "unprognostic (4.89e-2)" "unprognostic (1.25e-1)" "unprognostic (5.53e-2)" "unprognostic (9.51e-3)" "unprognostic (4.39e-1)" "unprognostic (2.72e-1)" "unprognostic (2.12e-2)" "unprognostic (9.66e-2)" "unprognostic (1.01e-1)" "unprognostic (1.08e-1)" "unprognostic (4.25e-2)" "unprognostic (1.56e-1)" "unprognostic (1.53e-1)" SMARCA1 "hSNF2L, ISWI, NURF140, SNF2L, SNF2L1, SNF2LB, SWI" ENSG00000102038 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1" P28370 X 129446501-129523500 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Leydig cells: 241.4;Sertoli cells: 487.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD4 T-cell: 1.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Minor Salivary Gland - Smooth muscle cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003335, HPA064712" Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 75: Ovary - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 5: Rhabdoid - Unknown function" "Cluster 94: Gonadal somatic cells - Mixed function" 56 Nucleoplasm Vesicles "HPA003335: , HPA064712: " "unprognostic (1.61e-1)" "unprognostic (2.12e-2)" "unprognostic (1.22e-1)" "unprognostic (1.16e-2)" "unprognostic (1.64e-1)" "unprognostic (3.01e-1)" "unprognostic (1.36e-1)" "unprognostic (5.03e-3)" "unprognostic (3.40e-2)" "unprognostic (1.97e-2)" "potential prognostic favorable (5.16e-6)" "unprognostic (1.35e-1)" "unprognostic (2.12e-2)" "unprognostic (4.80e-2)" "unprognostic (1.46e-3)" "unprognostic (9.20e-3)" "unprognostic (9.39e-2)" "unprognostic (1.82e-1)" "unprognostic (4.19e-1)" "unprognostic (6.92e-2)" "unprognostic (8.32e-2)" "potential prognostic favorable (7.41e-4)" "potential prognostic unfavorable (3.71e-5)" "unprognostic (5.38e-2)" "unprognostic (2.67e-1)" "unprognostic (1.19e-1)" "unprognostic (1.89e-2)" "potential prognostic unfavorable (8.37e-4)" "unprognostic (2.00e-1)" "unprognostic (2.42e-1)" "unprognostic (2.55e-1)" SMARCA2 "BAF190, BRM, hBRM, hSNF2a, SNF2, SNF2L2, SNF2LA, Sth1p, SWI2" ENSG00000080503 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2" P51531 9 1980290-2193624 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" "Activator, DNA-binding, Hydrolase" "Disease variant, Hypotrichosis, Intellectual disability, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Innate lymphoid cells: 690.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "HPA029981, CAB037276" Enhanced Supported "Nucleoplasm,Vesicles,Plasma membrane" NA NA 1400000 "Cluster 45: Eosinophils - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 15: Non-specific - Transcription" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 85 Nucleoplasm "Vesicles, Plasma membrane" "CAB037276: , HPA029981: " "potential prognostic favorable (2.03e-4)" "unprognostic (1.77e-1)" "unprognostic (1.81e-1)" "unprognostic (7.75e-2)" "unprognostic (1.09e-1)" "unprognostic (4.47e-3)" "unprognostic (7.43e-2)" "unprognostic (5.39e-2)" "unprognostic (8.51e-2)" "unprognostic (6.71e-3)" "validated prognostic favorable (2.55e-6)" "validated prognostic favorable (5.48e-4)" "unprognostic (1.53e-1)" "unprognostic (4.81e-2)" "unprognostic (1.13e-2)" "unprognostic (2.55e-2)" "unprognostic (1.36e-1)" "unprognostic (2.08e-1)" "unprognostic (2.19e-2)" "unprognostic (2.02e-1)" "unprognostic (9.70e-2)" "unprognostic (8.97e-3)" "unprognostic (3.75e-1)" "unprognostic (1.65e-1)" "unprognostic (3.19e-3)" "unprognostic (2.44e-1)" "unprognostic (8.96e-2)" "unprognostic (1.86e-1)" "unprognostic (1.35e-1)" "unprognostic (1.73e-1)" "unprognostic (5.01e-2)" SMARCA4 "BAF190, BRG1, FLJ39786, hSNF2b, SNF2, SNF2-BETA, SNF2L4, SNF2LB, SWI2" ENSG00000127616 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4" P51532 19 10960932-11079426 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" "Activator, Chromatin regulator, Hydrolase, Repressor, RNA-binding" "Cancer-related genes, Deafness, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 342.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004208, HPA048340" Supported Supported "Nucleoplasm,Nucleoli fibrillar center,Nucleoli rim" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 39: Testis - Nuclear processes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 232 "Nucleoplasm, Nucleoli fibrillar center, Nucleoli rim" "CAB004208: , HPA048340: " "unprognostic (6.70e-2)" "unprognostic (3.03e-2)" "unprognostic (1.15e-1)" "unprognostic (1.98e-1)" "unprognostic (8.09e-2)" "unprognostic (3.24e-1)" "unprognostic (1.91e-1)" "unprognostic (3.08e-2)" "unprognostic (3.06e-2)" "unprognostic (7.14e-2)" "unprognostic (3.56e-2)" "unprognostic (2.66e-1)" "unprognostic (3.02e-2)" "validated prognostic unfavorable (1.42e-4)" "validated prognostic unfavorable (2.19e-5)" "unprognostic (5.87e-2)" "unprognostic (4.99e-3)" "unprognostic (8.85e-2)" "unprognostic (1.02e-2)" "unprognostic (2.54e-2)" "unprognostic (8.28e-2)" "unprognostic (1.55e-1)" "unprognostic (3.23e-3)" "unprognostic (3.56e-2)" "unprognostic (1.18e-1)" "unprognostic (4.06e-2)" "potential prognostic unfavorable (8.18e-6)" "unprognostic (6.01e-2)" "unprognostic (8.14e-2)" "unprognostic (3.17e-1)" "unprognostic (1.30e-1)" SMARCA5 "hISWI, hSNF2H, ISWI" ENSG00000153147 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5" O60264 4 143513702-143557486 "Essential proteins, Predicted intracellular proteins, Transcription factors" "Host-virus interaction" "Chromatin regulator, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005227, HPA008751" Supported Supported "Nucleoplasm,Nucleoli fibrillar center" No No 4200 "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 17: Non-specific - RNA processing" 143 Nucleoplasm "Nucleoli fibrillar center" "CAB005227: , HPA008751: " "unprognostic (6.74e-2)" "unprognostic (8.31e-3)" "unprognostic (1.35e-2)" "unprognostic (1.62e-2)" "unprognostic (3.43e-2)" "unprognostic (5.00e-2)" "unprognostic (1.92e-1)" "unprognostic (2.09e-1)" "unprognostic (1.97e-1)" "unprognostic (9.65e-3)" "validated prognostic favorable (2.03e-6)" "validated prognostic favorable (2.05e-4)" "unprognostic (8.58e-2)" "potential prognostic unfavorable (1.68e-4)" "unprognostic (2.01e-1)" "unprognostic (1.16e-1)" "unprognostic (1.23e-1)" "unprognostic (9.81e-2)" "unprognostic (4.72e-2)" "unprognostic (2.55e-2)" "unprognostic (3.57e-3)" "unprognostic (1.16e-1)" "unprognostic (4.09e-2)" "unprognostic (6.46e-2)" "unprognostic (7.98e-2)" "unprognostic (2.47e-2)" "unprognostic (1.07e-1)" "unprognostic (2.67e-1)" "unprognostic (4.86e-1)" "unprognostic (5.09e-2)" "unprognostic (2.36e-1)" SMARCAD1 "DKFZP762K2015, ETL1, KIAA1122" ENSG00000163104 "SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1" Q9H4L7 4 94207611-94291292 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Ectodermal dysplasia, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016737 Approved Enhanced Nucleoplasm NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 7: Non-specific - Transcription" 29 Nucleoplasm "HPA016737: " "unprognostic (2.12e-1)" "unprognostic (4.92e-3)" "unprognostic (4.91e-1)" "unprognostic (1.19e-2)" "unprognostic (9.53e-2)" "unprognostic (3.44e-1)" "unprognostic (3.89e-2)" "unprognostic (2.58e-2)" "unprognostic (2.02e-2)" "potential prognostic unfavorable (5.35e-5)" "potential prognostic favorable (6.23e-5)" "unprognostic (2.01e-3)" "unprognostic (4.17e-2)" "potential prognostic unfavorable (2.91e-5)" "unprognostic (2.96e-1)" "unprognostic (1.25e-1)" "unprognostic (5.20e-2)" "unprognostic (3.16e-1)" "unprognostic (1.06e-3)" "unprognostic (1.04e-1)" "unprognostic (9.27e-2)" "unprognostic (1.04e-1)" "unprognostic (2.23e-2)" "unprognostic (1.02e-1)" "unprognostic (1.94e-3)" "unprognostic (1.95e-3)" "unprognostic (9.90e-3)" "unprognostic (1.20e-1)" "unprognostic (3.11e-1)" "unprognostic (7.75e-2)" "unprognostic (8.89e-2)" SMARCAL1 "HARP, HHARP" ENSG00000138375 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1" Q9NZC9 2 216412383-216483053 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020337 Uncertain Supported Nucleoplasm NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 54: Non-specific - Ribosome" "Cluster 11: White matter - Signal transduction" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 7: Non-specific - Transcription" 10 Nucleoplasm "HPA020337: " "unprognostic (1.06e-1)" "unprognostic (4.40e-2)" "unprognostic (9.93e-2)" "unprognostic (4.82e-2)" "unprognostic (3.66e-1)" "unprognostic (1.57e-1)" "unprognostic (1.09e-1)" "unprognostic (5.06e-2)" "unprognostic (3.47e-2)" "unprognostic (9.93e-2)" "potential prognostic favorable (6.24e-4)" "unprognostic (1.62e-1)" "unprognostic (1.40e-3)" "potential prognostic unfavorable (1.03e-4)" "unprognostic (9.08e-3)" "unprognostic (2.81e-3)" "unprognostic (1.40e-2)" "unprognostic (6.28e-2)" "unprognostic (5.47e-1)" "unprognostic (1.57e-1)" "unprognostic (1.70e-1)" "unprognostic (1.65e-1)" "unprognostic (3.51e-3)" "unprognostic (4.59e-1)" "unprognostic (6.25e-2)" "unprognostic (1.84e-1)" "unprognostic (3.23e-2)" "unprognostic (2.72e-1)" "unprognostic (4.34e-2)" "unprognostic (1.26e-1)" "unprognostic (2.20e-1)" SMARCB1 "BAF47, hSNFS, INI-1, Ini1, PPP1R144, RDT, Sfh1p, SNF5, SNF5L1, Snr1" ENSG00000099956 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1" Q12824 22 23786931-23838009 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Host-virus interaction, Neurogenesis, Transcription, Transcription regulation" "Activator, Chromatin regulator, DNA-binding" "Cancer-related genes, Disease variant, Hypotrichosis, Intellectual disability, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oocytes: 82.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Myeloma: 24.4" "Spleen - B-cells (Spleen), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009196, HPA018248, HPA019127" Supported Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 64: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 67: Plasma cells - Plasma cell differentiation" 165 Nucleoplasm "Nucleoli fibrillar center" "CAB009196: , HPA018248: , HPA019127: " "potential prognostic favorable (3.58e-4)" "unprognostic (4.06e-3)" "unprognostic (9.16e-3)" "unprognostic (1.63e-1)" "unprognostic (6.75e-3)" "unprognostic (5.87e-2)" "unprognostic (3.29e-2)" "unprognostic (5.30e-2)" "unprognostic (5.94e-3)" "unprognostic (1.64e-1)" "unprognostic (1.31e-2)" "unprognostic (2.20e-2)" "unprognostic (3.35e-1)" "unprognostic (1.18e-1)" "potential prognostic unfavorable (2.07e-4)" "unprognostic (5.95e-2)" "unprognostic (2.29e-2)" "unprognostic (3.56e-2)" "unprognostic (1.31e-2)" "unprognostic (3.26e-1)" "unprognostic (1.05e-1)" "unprognostic (1.59e-1)" "unprognostic (1.44e-2)" "unprognostic (4.31e-2)" "unprognostic (1.00e-1)" "unprognostic (1.24e-1)" "unprognostic (3.58e-2)" "unprognostic (3.11e-1)" "unprognostic (2.09e-1)" "unprognostic (3.62e-2)" "unprognostic (1.51e-1)" SMARCC1 "BAF155, CRACC1, Rsc8, SRG3" ENSG00000173473 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1" Q92922 3 47585269-47782106 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Neurogenesis, Transcription, Transcription regulation" "Chromatin regulator" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011576, CAB016336, HPA024352, HPA026853" Supported Enhanced Nucleoplasm NA NA 6400 "Cluster 5: Non-specific - Cell proliferation" "Cluster 80: Thymus - Adaptive immune response" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 51: Secretory epithelial cells - Mixed function" 155 Nucleoplasm "CAB011576: , CAB016336: , HPA024352: , HPA026853: " "unprognostic (4.86e-3)" "unprognostic (7.13e-2)" "unprognostic (2.30e-1)" "unprognostic (3.03e-2)" "unprognostic (1.79e-1)" "unprognostic (1.59e-1)" "unprognostic (4.36e-2)" "unprognostic (6.80e-2)" "unprognostic (1.79e-1)" "unprognostic (2.35e-3)" "unprognostic (1.10e-3)" "unprognostic (8.68e-2)" "unprognostic (1.85e-1)" "validated prognostic unfavorable (3.97e-4)" "validated prognostic unfavorable (1.90e-5)" "unprognostic (1.12e-1)" "potential prognostic unfavorable (6.62e-4)" "unprognostic (5.76e-2)" "unprognostic (1.83e-1)" "unprognostic (8.11e-2)" "unprognostic (6.13e-3)" "unprognostic (4.47e-2)" "unprognostic (1.73e-1)" "unprognostic (3.58e-2)" "unprognostic (1.56e-3)" "unprognostic (7.23e-2)" "unprognostic (1.49e-2)" "unprognostic (3.02e-1)" "unprognostic (2.52e-1)" "unprognostic (4.83e-3)" "unprognostic (3.76e-2)" SMARCC2 "BAF170, CRACC2, Rsc8" ENSG00000139613 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2" Q8TAQ2 12 56162359-56189567 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Neurogenesis, Transcription, Transcription regulation" "Chromatin regulator" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 62.1;Loop of henle epithelial cells: 55.8;Papillary tip epithelial cells: 58.9;Podocytes: 64.8;Renal collecting duct intercalated cells: 57.8;Renal collecting duct principal cells: 57.9;Renal connecting tubule cells: 58.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pancreas - Endothelial cells, Spleen - Endothelial cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004321, HPA021213, HPA061788" Supported Enhanced Nucleoplasm NA NA 8900 "Cluster 45: Eosinophils - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 38: Non-specific - Transcription" "Cluster 105: Non-specific - Mixed function" 140 Nucleoplasm "CAB004321: , HPA021213: , HPA061788: " "unprognostic (7.37e-2)" "unprognostic (2.14e-2)" "unprognostic (1.67e-1)" "unprognostic (1.04e-2)" "unprognostic (1.58e-1)" "unprognostic (5.66e-2)" "unprognostic (2.55e-2)" "unprognostic (1.56e-2)" "unprognostic (1.45e-1)" "unprognostic (1.15e-2)" "unprognostic (1.46e-2)" "unprognostic (6.82e-3)" "unprognostic (1.20e-1)" "unprognostic (4.41e-3)" "unprognostic (1.59e-1)" "unprognostic (1.37e-1)" "unprognostic (1.11e-1)" "unprognostic (1.10e-1)" "unprognostic (3.45e-1)" "unprognostic (1.99e-1)" "unprognostic (8.54e-2)" "unprognostic (5.34e-2)" "unprognostic (9.97e-3)" "unprognostic (3.33e-1)" "unprognostic (1.27e-1)" "unprognostic (1.20e-1)" "unprognostic (9.58e-3)" "unprognostic (3.05e-1)" "unprognostic (1.20e-1)" "unprognostic (2.09e-2)" "unprognostic (5.10e-2)" SMARCD1 "BAF60A, CRACD1, Rsc6p" ENSG00000066117 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1" Q96GM5 12 50085200-50100707 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Neurogenesis "Chromatin regulator" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004101 Supported Supported Nucleoplasm,Vesicles NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 80: Thymus - Adaptive immune response" "Cluster 34: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 189 Nucleoplasm Vesicles "HPA004101: " "unprognostic (1.34e-1)" "unprognostic (1.47e-1)" "unprognostic (6.38e-2)" "unprognostic (4.35e-2)" "unprognostic (1.87e-1)" "unprognostic (6.54e-2)" "unprognostic (3.16e-1)" "unprognostic (1.25e-2)" "unprognostic (2.68e-1)" "unprognostic (5.06e-2)" "unprognostic (2.67e-1)" "unprognostic (4.60e-1)" "unprognostic (1.80e-1)" "potential prognostic unfavorable (6.37e-7)" "unprognostic (3.60e-3)" "unprognostic (4.08e-2)" "unprognostic (6.45e-2)" "unprognostic (1.87e-2)" "unprognostic (7.35e-2)" "unprognostic (1.04e-1)" "unprognostic (1.18e-1)" "unprognostic (2.41e-1)" "unprognostic (5.13e-3)" "unprognostic (8.21e-3)" "unprognostic (1.69e-1)" "unprognostic (1.94e-2)" "unprognostic (2.28e-1)" "unprognostic (3.48e-1)" "unprognostic (1.43e-1)" "unprognostic (6.24e-2)" "unprognostic (2.14e-2)" SMARCD2 "BAF60B, CRACD2, PRO2451, Rsc6p" ENSG00000108604 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2" Q92925 17 63832081-63843065 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059934, HPA061348" Enhanced Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 58: Skin - Keratinization" "Cluster 25: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 108: Fibroblasts - ECM organization" 73 Nucleoplasm "HPA059934: , HPA061348: " "unprognostic (1.60e-1)" "unprognostic (1.28e-1)" "unprognostic (1.03e-1)" "unprognostic (1.60e-2)" "unprognostic (1.15e-1)" "unprognostic (3.03e-1)" "unprognostic (2.64e-1)" "unprognostic (2.39e-1)" "unprognostic (1.47e-2)" "unprognostic (1.89e-3)" "unprognostic (7.40e-2)" "unprognostic (4.18e-1)" "unprognostic (2.21e-2)" "unprognostic (8.68e-3)" "potential prognostic unfavorable (1.66e-5)" "unprognostic (6.10e-2)" "unprognostic (1.41e-3)" "unprognostic (1.90e-1)" "unprognostic (1.14e-3)" "unprognostic (2.94e-1)" "unprognostic (2.78e-1)" "unprognostic (2.00e-1)" "unprognostic (2.92e-1)" "unprognostic (1.59e-1)" "unprognostic (8.30e-2)" "unprognostic (5.49e-2)" "unprognostic (1.12e-1)" "unprognostic (8.45e-3)" "unprognostic (1.89e-1)" "unprognostic (1.94e-1)" "unprognostic (2.23e-2)" SMARCD3 "BAF60C, CRACD3, Rsc6p" ENSG00000082014 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3" Q6STE5 7 151238764-151277896 "Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 148.9;skeletal muscle: 120.5" "Cell type enhanced" "Detected in many" "Breast lactating cells: 159.6;Myonuclei: 135.5;Neutrophils: 107.1;Pericytes: 88.1;Peritubular myoid cells: 107.0;Vascular smooth muscle cells: 120.9" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 109.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 5.5" "Group enriched" "Detected in many" 5 "dendritic cells: 1.6;granulocytes: 1.9;monocytes: 5.5" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063955, HPA065517" Uncertain Enhanced Nucleoplasm NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 51: Neurons - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 110: Mural cells - ECM organization" 22 Nucleoplasm "HPA063955: , HPA065517: " "unprognostic (2.11e-2)" "unprognostic (2.46e-2)" "unprognostic (1.44e-1)" "unprognostic (2.42e-2)" "unprognostic (1.30e-1)" "unprognostic (3.65e-3)" "unprognostic (2.87e-2)" "unprognostic (4.71e-2)" "unprognostic (2.31e-3)" "unprognostic (5.24e-2)" "unprognostic (5.11e-2)" "unprognostic (1.15e-1)" "unprognostic (1.20e-2)" "unprognostic (2.84e-2)" "unprognostic (7.05e-2)" "potential prognostic favorable (5.62e-6)" "unprognostic (2.00e-1)" "unprognostic (2.91e-2)" "unprognostic (1.05e-1)" "unprognostic (3.86e-2)" "unprognostic (5.37e-3)" "potential prognostic favorable (8.70e-4)" "unprognostic (1.54e-1)" "unprognostic (1.11e-1)" "unprognostic (1.80e-1)" "unprognostic (3.77e-2)" "unprognostic (4.69e-2)" "unprognostic (3.48e-3)" "unprognostic (1.20e-1)" "unprognostic (1.26e-1)" "unprognostic (2.41e-1)" SMARCE1 BAF57 ENSG00000073584 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1" Q969G3 17 40624962-40648654 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" Neurogenesis "Chromatin regulator, DNA-binding" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003916, CAB037318" Supported Supported Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 61: Non-specific - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 27: Breast cancer - Unknown function" "Cluster 17: Non-specific - RNA processing" 166 Nucleoplasm "CAB037318: , HPA003916: " "unprognostic (3.49e-2)" "unprognostic (2.92e-1)" "unprognostic (2.05e-1)" "unprognostic (5.22e-3)" "unprognostic (1.72e-1)" "unprognostic (6.54e-2)" "unprognostic (5.47e-2)" "unprognostic (4.48e-2)" "unprognostic (3.02e-2)" "unprognostic (1.69e-3)" "potential prognostic favorable (6.00e-4)" "unprognostic (6.34e-3)" "unprognostic (1.21e-1)" "unprognostic (1.12e-2)" "unprognostic (1.48e-3)" "unprognostic (2.05e-2)" "unprognostic (5.27e-2)" "unprognostic (4.43e-1)" "unprognostic (9.37e-3)" "unprognostic (5.06e-2)" "unprognostic (1.35e-1)" "unprognostic (3.44e-3)" "unprognostic (1.02e-1)" "unprognostic (2.58e-1)" "unprognostic (8.96e-3)" "unprognostic (2.04e-2)" "unprognostic (3.44e-2)" "unprognostic (4.28e-2)" "unprognostic (1.71e-1)" "unprognostic (7.21e-2)" "unprognostic (4.61e-2)" SMC1A "DXS423E, KIAA0178, SB1.8, SMC1L1, Smcb" ENSG00000072501 "Structural maintenance of chromosomes 1A" Q14683 X 53374149-53422728 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Meiosis, Mitosis" "Cancer-related genes, Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythrocyte progenitors: 240.8;Monocyte progenitors: 275.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005499, HPA005500, CAB025404" Supported Enhanced Nucleoplasm,Cytosol NA NA 15000 "Cluster 33: Non-specific - ATP binding" "Cluster 80: Thymus - Adaptive immune response" "Cluster 25: Non-specific - Transcription" "Cluster 36: Non-specific - mRNA processing" "Cluster 27: Non-specific - Cell proliferation" 135 Nucleoplasm Cytosol "CAB025404: , HPA005499: , HPA005500: " "unprognostic (1.77e-1)" "unprognostic (1.17e-1)" "unprognostic (4.56e-2)" "unprognostic (1.23e-1)" "unprognostic (1.75e-2)" "unprognostic (7.18e-3)" "unprognostic (1.16e-1)" "unprognostic (1.72e-1)" "unprognostic (1.89e-1)" "unprognostic (3.13e-3)" "potential prognostic favorable (6.91e-4)" "unprognostic (2.67e-2)" "unprognostic (2.38e-1)" "unprognostic (2.85e-2)" "potential prognostic unfavorable (2.82e-4)" "unprognostic (6.54e-2)" "unprognostic (1.32e-2)" "unprognostic (1.68e-1)" "unprognostic (8.63e-2)" "unprognostic (2.95e-2)" "unprognostic (6.26e-2)" "unprognostic (2.82e-2)" "unprognostic (1.96e-1)" "unprognostic (1.38e-1)" "unprognostic (2.93e-2)" "unprognostic (1.99e-2)" "potential prognostic unfavorable (6.15e-4)" "unprognostic (4.75e-2)" "unprognostic (1.36e-1)" "unprognostic (6.60e-2)" "unprognostic (8.92e-2)" SMC1B "bK268H5, SMC1L2" ENSG00000077935 "Structural maintenance of chromosomes 1B" Q8NDV3 22 45344063-45413619 "Predicted intracellular proteins" "Cell cycle, Meiosis" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 97 "testis: 29.0" "Group enriched" "Detected in many" 8 "Differentiating spermatogonia: 511.1;Early primary spermatocytes: 1348.9" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in some" 6 "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 7.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Spermatocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA001500 Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 3: Early primary spermatocytes - Early meiosis" 2 "Nucleoplasm, Cytosol" "HPA001500: " "unprognostic (2.06e-1)" "unprognostic (8.48e-3)" "unprognostic (7.11e-2)" "unprognostic (2.04e-1)" "unprognostic (1.46e-2)" SMC2 "CAP-E, hCAP-E, SMC2L1" ENSG00000136824 "Structural maintenance of chromosomes 2" O95347 9 104094260-104141419 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 24.0" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 120.6;Endometrial ciliated cells: 142.7;Epididymal efferent duct ciliated cells: 128.4;Erythrocyte progenitors: 251.2;Megakaryocyte progenitors: 187.1;Monocyte progenitors: 185.1;Oocytes: 124.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071309 Approved Supported Nucleoplasm,Nucleoli Yes No 9100 "Cluster 33: Non-specific - ATP binding" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Cell proliferation" 47 Nucleoplasm Nucleoli "HPA071309: " "unprognostic (3.71e-2)" "unprognostic (1.57e-1)" "unprognostic (1.54e-3)" "unprognostic (7.71e-2)" "unprognostic (1.10e-1)" "unprognostic (5.55e-2)" "unprognostic (2.12e-1)" "unprognostic (8.00e-2)" "unprognostic (1.20e-1)" "unprognostic (3.94e-2)" "potential prognostic favorable (6.85e-7)" "unprognostic (4.45e-2)" "unprognostic (1.14e-1)" "unprognostic (2.35e-3)" "potential prognostic unfavorable (4.22e-4)" "potential prognostic unfavorable (4.44e-5)" "unprognostic (1.70e-3)" "unprognostic (2.02e-1)" "unprognostic (1.33e-1)" "unprognostic (2.03e-1)" "unprognostic (2.43e-2)" "unprognostic (2.01e-2)" "unprognostic (9.00e-2)" "unprognostic (5.88e-2)" "unprognostic (5.28e-3)" "unprognostic (7.42e-2)" "unprognostic (2.39e-2)" "unprognostic (5.48e-2)" "unprognostic (1.62e-1)" "unprognostic (2.69e-1)" "unprognostic (2.83e-1)" SMC3 "BAM, bamacan, CSPG6, HCAP, SMC3L1" ENSG00000108055 "Structural maintenance of chromosomes 3" Q9UQE7 10 110567684-110606048 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Meiosis, Mitosis" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 703.6;Early primary spermatocytes: 1402.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043206 Approved Supported Nucleoplasm NA NA 26000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 3: Early primary spermatocytes - Early meiosis" 101 Nucleoplasm "HPA043206: " "unprognostic (5.34e-2)" "unprognostic (9.22e-2)" "unprognostic (1.73e-2)" "unprognostic (2.55e-2)" "unprognostic (8.34e-2)" "unprognostic (6.80e-3)" "unprognostic (5.22e-2)" "potential prognostic favorable (3.30e-4)" "unprognostic (3.10e-2)" "unprognostic (4.32e-3)" "validated prognostic favorable (1.96e-5)" "validated prognostic favorable (6.27e-4)" "unprognostic (8.06e-3)" "unprognostic (2.25e-3)" "unprognostic (2.21e-3)" "unprognostic (2.63e-2)" "unprognostic (1.08e-2)" "unprognostic (2.00e-1)" "unprognostic (3.94e-2)" "unprognostic (2.82e-2)" "potential prognostic unfavorable (9.23e-4)" "unprognostic (5.71e-2)" "unprognostic (2.76e-3)" "unprognostic (1.03e-2)" "unprognostic (3.59e-3)" "unprognostic (2.58e-3)" "unprognostic (2.30e-1)" "unprognostic (1.11e-1)" "unprognostic (1.69e-1)" "unprognostic (1.54e-1)" "unprognostic (2.19e-1)" SMC4 "CAP-C, hCAP-C, SMC4L1" ENSG00000113810 "Structural maintenance of chromosomes 4" Q9NTJ3 3 160399274-160434954 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 56.4" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 307.3;Early primary spermatocytes: 387.3;Erythrocyte progenitors: 485.0;Esophageal apical cells: 927.7;Megakaryocyte progenitors: 283.4;Monocyte progenitors: 495.2;Neutrophil progenitors: 271.7" "Cell type enhanced" "Detected in all" "leukocyte: 56.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 74.6" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029449, CAB055509" Approved Supported "Nuclear speckles,Cytosol" NA Yes 13000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 11: White matter - Signal transduction" "Cluster 63: Non-specific - Protein processing" "Cluster 27: Non-specific - Cell proliferation" 37 "Nuclear speckles, Cytosol" "CAB055509: , HPA029449: " "unprognostic (6.87e-2)" "unprognostic (1.74e-1)" "unprognostic (2.31e-2)" "unprognostic (1.09e-2)" "unprognostic (1.06e-1)" "unprognostic (1.54e-1)" "unprognostic (2.17e-1)" "unprognostic (2.44e-1)" "unprognostic (1.72e-1)" "unprognostic (4.20e-3)" "potential prognostic favorable (5.54e-5)" "unprognostic (2.06e-1)" "unprognostic (4.45e-2)" "unprognostic (3.10e-2)" "unprognostic (9.99e-3)" "unprognostic (8.27e-3)" "unprognostic (3.87e-2)" "unprognostic (4.82e-2)" "unprognostic (3.64e-3)" "unprognostic (2.77e-1)" "unprognostic (3.83e-2)" "validated prognostic unfavorable (3.84e-6)" "validated prognostic unfavorable (2.14e-4)" "potential prognostic unfavorable (1.52e-4)" "unprognostic (3.25e-2)" "unprognostic (7.09e-2)" "unprognostic (6.02e-2)" "unprognostic (2.63e-2)" "unprognostic (2.76e-1)" "unprognostic (1.26e-2)" "unprognostic (4.82e-2)" SMC5 "KIAA0594, SMC5L1" ENSG00000198887 "Structural maintenance of chromosomes 5" Q8IY18 9 70258978-70354873 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA recombination, DNA repair, Mitosis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" HPA054900 Supported Supported "Nuclear speckles" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 54: Non-specific - Ribosome" "Cluster 55: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 103: Non-specific - Basic cellular processes" 30 "Nuclear speckles" "HPA054900: " "unprognostic (4.30e-1)" "unprognostic (3.20e-1)" "unprognostic (1.73e-2)" "unprognostic (1.67e-1)" "unprognostic (5.37e-2)" "unprognostic (7.67e-2)" "unprognostic (2.79e-1)" "unprognostic (1.09e-1)" "unprognostic (2.86e-2)" "unprognostic (3.38e-3)" "validated prognostic favorable (6.63e-5)" "validated prognostic favorable (1.10e-4)" "unprognostic (2.52e-1)" "unprognostic (4.99e-3)" "unprognostic (2.05e-1)" "unprognostic (2.78e-1)" "unprognostic (1.17e-1)" "unprognostic (3.74e-1)" "unprognostic (8.13e-2)" "unprognostic (1.08e-1)" "unprognostic (2.74e-1)" "unprognostic (9.41e-2)" "unprognostic (2.01e-2)" "unprognostic (2.02e-1)" "unprognostic (6.12e-2)" "unprognostic (3.67e-1)" "unprognostic (1.01e-1)" "unprognostic (6.24e-2)" "unprognostic (2.69e-1)" "unprognostic (2.10e-1)" "unprognostic (1.60e-1)" SMC6 "FLJ22116, SMC6L1" ENSG00000163029 "Structural maintenance of chromosomes 6" Q96SB8 2 17663812-17800242 "Essential proteins, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 308.7;Choroid plexus epithelial cells: 333.1;Gonadotrophs: 563.4;Retinal pigment epithelial cells: 891.0;Sertoli cells: 530.0" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 496.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035057, CAB037186, HPA042733" Uncertain Supported Nucleoplasm NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 39: Testis - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 55: Lymphoma - Immune response" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" 33 Nucleoplasm "CAB037186: , HPA035057: , HPA042733: " "unprognostic (1.52e-1)" "unprognostic (2.35e-1)" "unprognostic (1.39e-1)" "unprognostic (1.74e-1)" "unprognostic (1.28e-1)" "unprognostic (6.07e-3)" "unprognostic (3.77e-2)" "unprognostic (1.57e-3)" "unprognostic (1.43e-2)" "unprognostic (1.52e-2)" "unprognostic (1.21e-3)" "unprognostic (1.94e-2)" "unprognostic (5.64e-2)" "unprognostic (3.08e-3)" "unprognostic (3.80e-1)" "unprognostic (1.05e-2)" "unprognostic (6.18e-2)" "unprognostic (2.83e-2)" "unprognostic (9.87e-2)" "unprognostic (7.11e-2)" "unprognostic (1.89e-1)" "unprognostic (1.51e-2)" "unprognostic (1.34e-3)" "unprognostic (6.33e-2)" "unprognostic (1.07e-2)" "unprognostic (9.87e-2)" "unprognostic (7.62e-2)" "unprognostic (7.47e-2)" "unprognostic (4.16e-1)" "unprognostic (9.89e-2)" "unprognostic (4.48e-3)" SMCHD1 "FSHD2, KIAA0650" ENSG00000101596 "Structural maintenance of chromosomes flexible hinge domain containing 1" A6NHR9 18 2655726-2805017 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "Chromatin regulator, DNA-binding, Hydrolase" "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Neutrophils: 6076.2" "Cell type enhanced" "Detected in all" "leukocyte: 806.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 10 "neutrophil: 44.2" "Lineage enriched" "Detected in all" 11 "granulocytes: 44.2" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039341, HPA039441" Approved Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 13: Non-specific - Mixed function" "Cluster 24: Neutrophils - Innate immunity signal integration" 16 Nucleoplasm "Nuclear bodies" "HPA039341: , HPA039441: " "unprognostic (2.77e-1)" "unprognostic (8.59e-2)" "unprognostic (1.62e-1)" "unprognostic (3.45e-1)" "unprognostic (3.04e-1)" "unprognostic (9.82e-3)" "unprognostic (7.31e-2)" "unprognostic (4.42e-2)" "unprognostic (1.16e-2)" "unprognostic (1.34e-2)" "unprognostic (1.85e-2)" "unprognostic (1.21e-1)" "unprognostic (9.61e-3)" "unprognostic (1.40e-3)" "unprognostic (1.71e-1)" "unprognostic (1.25e-1)" "unprognostic (2.03e-1)" "unprognostic (1.65e-2)" "unprognostic (3.64e-3)" "unprognostic (4.10e-2)" "unprognostic (8.44e-2)" "unprognostic (1.53e-1)" "unprognostic (3.50e-3)" "unprognostic (3.26e-2)" "unprognostic (3.51e-3)" "unprognostic (1.11e-1)" "unprognostic (5.74e-3)" "unprognostic (1.93e-1)" "unprognostic (1.90e-1)" "unprognostic (3.22e-2)" "unprognostic (8.31e-2)" SMCO1 "C3orf43, DKFZp313B0440, FLJ41923" ENSG00000214097 "Single-pass membrane protein with coiled-coil domains 1" Q147U7 3 196506879-196515346 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 41 "heart muscle: 39.4;skeletal muscle: 139.7;tongue: 99.9" "Cell type enriched" "Detected in some" 4 "Myonuclei: 47.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA061937 Approved "Endoplasmic reticulum,Golgi apparatus" NA NA "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 3 "Golgi apparatus" "Endoplasmic reticulum" "HPA061937: " SMCO2 "C12orf70, LOC341346" ENSG00000165935 "Single-pass membrane protein with coiled-coil domains 2" A6NFE2 12 27446736-27502185 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 6.8;Early spermatids: 12.4;Epicardial cells: 6.8;Esophageal apical cells: 21.4;Foveolar cells: 6.8;Hematopoietic stem cells: 19.4;Late primary spermatocytes: 15.2;Megakaryocyte-Erythroid progenitors: 7.5;Retinal ganglion cells: 7.7;Thymic myoid cells: 13.6;Thymocytes: 6.8" "Cell type enhanced" "Detected in many" "thalamic excitatory: 27.8" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Stomach - Gastric mucous cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA014366 Uncertain NA NA "Cluster 38: Sub-cortical - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 46: Skeletal myocytes - Muscle structure & formation" "HPA014366: " "unprognostic (8.19e-3)" "unprognostic (6.44e-2)" "potential prognostic unfavorable (9.65e-5)" SMCO3 "C12orf69, LOC440087" ENSG00000179256 "Single-pass membrane protein with coiled-coil domains 3" A2RU48 12 14804650-14814182 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 3.2;kidney: 2.8" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 27.6;Epicardial cells: 22.7;Podocytes: 11.4;Schwann cells: 7.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Prostate Adenocarcinoma (TCGA): 4.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Rhabdoid: 1.4" "Low region specificity" "Detected in all" "Region enriched" "Detected in single" 7 "spinal cord: 3.3" "HPA040574, HPA047804" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 4 "Plasma membrane" Cytosol "HPA040574: , HPA047804: " "unprognostic (3.24e-1)" "potential prognostic unfavorable (1.58e-4)" "unprognostic (1.72e-2)" "unprognostic (1.97e-1)" "unprognostic (4.45e-2)" SMCO4 "C11orf75, FN5" ENSG00000166002 "Single-pass membrane protein with coiled-coil domains 4" Q9NRQ5 11 93478472-93543391 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 184.0" "Cell type enhanced" "Detected in many" "Early spermatids: 156.3;Enterocytes: 186.1;Late spermatids: 253.4;Parietal cells: 206.8;Salivary acinar cells: 208.1" "Cell type enhanced" "Detected in many" "endothelial cell: 65.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Somatotropes, Prostate - Prostate glandular cells, Skin - Outer root sheath cells, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041120 Uncertain NA Yes "Cluster 10: Non-specific - Membrane trafficking" "Cluster 70: Non-specific - Protein processing" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 51 "HPA041120: " "unprognostic (1.57e-2)" "unprognostic (9.73e-3)" "unprognostic (1.92e-2)" "unprognostic (2.72e-1)" "unprognostic (1.56e-1)" "unprognostic (5.48e-2)" "unprognostic (2.18e-2)" "unprognostic (2.26e-2)" "potential prognostic unfavorable (7.32e-4)" "unprognostic (4.06e-2)" "unprognostic (4.81e-2)" "unprognostic (4.08e-1)" "unprognostic (1.58e-1)" "unprognostic (1.73e-1)" "unprognostic (1.10e-2)" "unprognostic (1.76e-1)" "unprognostic (2.55e-1)" "unprognostic (4.42e-2)" "unprognostic (1.23e-2)" "unprognostic (5.14e-2)" "unprognostic (1.74e-1)" "unprognostic (3.21e-1)" "unprognostic (3.11e-2)" "unprognostic (1.36e-2)" "unprognostic (7.36e-2)" "unprognostic (3.46e-1)" "unprognostic (1.03e-1)" "unprognostic (1.75e-1)" "unprognostic (1.21e-1)" SMCP MCSP ENSG00000163206 "Sperm mitochondria associated cysteine rich protein" P49901 1 152878322-152885047 "Predicted intracellular proteins" Fertilization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 576 "testis: 717.3" "Cell type enriched" "Detected in some" 6 "Late spermatids: 24930.0" "Cell type enriched" "Detected in single" 37 "Bergmann glia: 3.8" "Cancer enhanced" "Detected in single" "Testicular Germ Cell Tumor (TCGA): 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "HPA035105, HPA077113" Enhanced NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 70 "HPA035105: , HPA077113: " "unprognostic (1.39e-1)" SMCR8 "DENND8A, FLJ34716" ENSG00000176994 "SMCR8-C9orf72 complex subunit" Q8TEV9 17 18315293-18328056 "Predicted intracellular proteins" "Autophagy, Transcription, Transcription regulation" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 4.5;Bergmann glia: 3.5;Brain excitatory neurons: 6.0;Brain inhibitory neurons: 6.0;Choroid plexus epithelial cells: 11.3;Distal convoluted tubule cells: 6.7;Ependymal cells: 3.5;Loop of henle epithelial cells: 6.8;Microglia: 12.2;Oligodendrocyte progenitor cells: 3.6;Oligodendrocytes: 5.5;Other brain neurons: 5.7;Papillary tip epithelial cells: 3.8;Podocytes: 7.7;Proximal tubule cells: 9.1;Renal collecting duct intercalated cells: 8.7;Renal collecting duct principal cells: 5.5;Renal connecting tubule cells: 6.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.5" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021557, HPA024646" Uncertain Enhanced Nucleoplasm NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 49: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 102: Non-specific - Mixed function" 9 Nucleoplasm "HPA021557: , HPA024646: " "potential prognostic favorable (7.78e-4)" "unprognostic (7.54e-2)" "unprognostic (6.51e-2)" "unprognostic (1.32e-1)" "unprognostic (1.14e-1)" "unprognostic (2.71e-2)" "unprognostic (1.62e-1)" "unprognostic (3.82e-3)" "potential prognostic favorable (7.07e-4)" "unprognostic (5.23e-2)" "potential prognostic favorable (6.36e-6)" "unprognostic (2.62e-3)" "unprognostic (1.67e-1)" "unprognostic (1.12e-3)" "unprognostic (1.09e-2)" "unprognostic (2.72e-2)" "unprognostic (1.35e-1)" "unprognostic (1.32e-2)" "unprognostic (1.82e-1)" "unprognostic (1.15e-2)" "potential prognostic unfavorable (2.20e-4)" "unprognostic (4.03e-2)" "unprognostic (1.32e-2)" "unprognostic (1.78e-1)" "unprognostic (5.17e-3)" "unprognostic (1.59e-1)" "unprognostic (3.93e-1)" "unprognostic (3.04e-2)" "unprognostic (1.67e-1)" "unprognostic (3.49e-3)" "unprognostic (3.80e-2)" SMDT1 "C22orf32, DDDD, dJ186O1.1, EMRE" ENSG00000183172 "Single-pass membrane protein with aspartate rich tail 1" Q9H4I9 22 42079691-42084284 "Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 426.8;Parietal cells: 503.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032117, HPA060340" Uncertain Supported Nucleoplasm,Mitochondria NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - DNA binding" "Cluster 25: Non-specific - Ribosome" "Cluster 67: Plasma cells - Plasma cell differentiation" 10 Mitochondria Nucleoplasm "HPA032117: , HPA060340: " "unprognostic (3.55e-2)" "unprognostic (8.03e-2)" "potential prognostic favorable (4.68e-5)" "unprognostic (1.03e-1)" "unprognostic (1.91e-1)" "unprognostic (6.15e-2)" "unprognostic (7.57e-3)" "unprognostic (9.66e-2)" "unprognostic (2.22e-1)" "validated prognostic favorable (1.01e-6)" "validated prognostic favorable (1.26e-5)" "unprognostic (8.00e-3)" "unprognostic (7.50e-3)" "unprognostic (8.25e-3)" "unprognostic (6.38e-3)" "unprognostic (3.26e-2)" "potential prognostic favorable (8.86e-4)" "unprognostic (5.25e-3)" "unprognostic (3.42e-2)" "potential prognostic favorable (6.57e-4)" "unprognostic (1.78e-1)" "unprognostic (3.35e-1)" "unprognostic (6.51e-2)" "unprognostic (1.29e-1)" "unprognostic (6.05e-2)" "unprognostic (8.54e-2)" "unprognostic (2.10e-1)" "unprognostic (1.97e-1)" "unprognostic (3.00e-2)" SMG1 "ATX, KIAA0421, LIP" ENSG00000157106 "SMG1 nonsense mediated mRNA decay associated PI3K related kinase" Q96Q15 16 18804860-18926408 "Enzymes, Essential proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Nonsense-mediated mRNA decay" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Myonuclei: 462.9;Thymic myoid cells: 610.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 34.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006870, HPA031623, HPA073972" Approved Supported "Nucleoplasm,Vesicles,Plasma membrane,Cell Junctions,Primary cilium" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 15: Non-specific - Transcription" "Cluster 54: Non-specific - Transcription" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 24 Nucleoplasm "Vesicles, Plasma membrane, Cell Junctions, Primary cilium" "HPA006870: , HPA031623: , HPA073972: " "unprognostic (4.88e-2)" "unprognostic (6.37e-2)" "unprognostic (2.50e-1)" "unprognostic (5.25e-2)" "unprognostic (1.53e-1)" "unprognostic (2.86e-1)" "unprognostic (4.95e-2)" "unprognostic (1.80e-2)" "unprognostic (1.25e-2)" "unprognostic (8.94e-3)" "unprognostic (5.32e-3)" "unprognostic (1.88e-3)" "unprognostic (3.88e-1)" "unprognostic (3.99e-2)" "unprognostic (2.55e-1)" "unprognostic (2.44e-1)" "unprognostic (9.31e-2)" "unprognostic (1.41e-1)" "unprognostic (6.32e-3)" "unprognostic (1.27e-1)" "unprognostic (3.80e-2)" "validated prognostic unfavorable (6.55e-5)" "validated prognostic unfavorable (1.90e-4)" "unprognostic (9.91e-2)" "potential prognostic favorable (1.53e-4)" "unprognostic (4.67e-3)" "unprognostic (2.34e-1)" "unprognostic (1.78e-1)" "unprognostic (1.95e-1)" "unprognostic (3.20e-2)" "unprognostic (1.86e-1)" SMG5 "EST1B, KIAA1089, LPTS-RP1, LPTSRP1, RP11-54H19.7, SMG-5" ENSG00000198952 "SMG5 nonsense mediated mRNA decay factor" Q9UPR3 1 156249224-156282825 "Essential proteins, Predicted membrane proteins" "Nonsense-mediated mRNA decay" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072651 Supported "Plasma membrane,Primary cilium,Cytoplasmic bodies" No No "Cluster 25: Non-specific - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 18: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 9 "Cytoplasmic bodies" "Plasma membrane, Primary cilium" "HPA072651: " "unprognostic (4.56e-2)" "unprognostic (5.33e-2)" "unprognostic (1.01e-1)" "unprognostic (1.95e-2)" "unprognostic (3.49e-1)" "unprognostic (2.99e-1)" "unprognostic (2.16e-1)" "potential prognostic favorable (7.31e-4)" "unprognostic (5.59e-3)" "unprognostic (1.19e-2)" "unprognostic (2.29e-2)" "unprognostic (6.78e-2)" "unprognostic (9.10e-3)" "potential prognostic unfavorable (9.06e-9)" "unprognostic (2.49e-2)" "unprognostic (5.48e-2)" "unprognostic (1.22e-3)" "unprognostic (9.50e-2)" "unprognostic (2.09e-1)" "unprognostic (4.92e-2)" "unprognostic (1.48e-1)" "unprognostic (1.25e-1)" "unprognostic (3.58e-2)" "unprognostic (2.92e-2)" "unprognostic (3.66e-2)" "unprognostic (1.09e-2)" "unprognostic (2.98e-2)" "unprognostic (4.16e-2)" "unprognostic (2.59e-1)" "unprognostic (2.77e-1)" "unprognostic (1.40e-2)" SMG6 "C17orf31, EST1A, KIAA0732, SMG-6" ENSG00000070366 "SMG6 nonsense mediated mRNA decay factor" Q86US8 17 2059839-2303785 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Nonsense-mediated mRNA decay" "DNA-binding, Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042932 Approved Supported "Nucleoli,Golgi apparatus,Plasma membrane,Primary cilium tip,Basal body,Cytosol" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 46: Brainstem - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 13 Nucleoli "Golgi apparatus, Plasma membrane, Primary cilium tip, Basal body, Cytosol" "HPA042932: " "unprognostic (2.34e-2)" "unprognostic (8.00e-2)" "unprognostic (1.23e-1)" "unprognostic (3.65e-2)" "unprognostic (2.50e-1)" "unprognostic (1.63e-1)" "unprognostic (2.67e-1)" "unprognostic (5.30e-3)" "potential prognostic favorable (2.75e-4)" "unprognostic (1.27e-3)" "validated prognostic favorable (2.64e-7)" "validated prognostic favorable (7.78e-4)" "unprognostic (5.99e-3)" "unprognostic (1.67e-1)" "unprognostic (6.85e-2)" "unprognostic (4.96e-2)" "unprognostic (1.02e-2)" "unprognostic (2.16e-1)" "unprognostic (1.87e-1)" "unprognostic (6.33e-2)" "unprognostic (2.16e-1)" "unprognostic (3.94e-2)" "unprognostic (2.71e-2)" "unprognostic (2.29e-1)" "unprognostic (2.12e-1)" "potential prognostic favorable (9.53e-4)" "unprognostic (2.26e-1)" "unprognostic (2.68e-2)" "unprognostic (3.24e-1)" "unprognostic (5.43e-2)" "unprognostic (8.22e-2)" SMG7 "C1orf16, EST1C, KIAA0250, SGA56M, SMG-7" ENSG00000116698 "SMG7 nonsense mediated mRNA decay factor" Q92540 1 183472216-183598246 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Nonsense-mediated mRNA decay" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 428.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029350, HPA076314" Supported Supported "Nucleoli,Nuclear speckles,Vesicles,Basal body,Cytosol" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 16: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 22 "Nucleoli, Cytosol" "Nuclear speckles, Vesicles, Basal body" "HPA029350: , HPA076314: " "unprognostic (8.71e-2)" "unprognostic (2.27e-2)" "unprognostic (3.32e-1)" "unprognostic (9.34e-2)" "unprognostic (6.27e-2)" "unprognostic (7.56e-2)" "unprognostic (2.85e-2)" "unprognostic (3.15e-1)" "unprognostic (1.20e-1)" "potential prognostic unfavorable (5.15e-4)" "potential prognostic favorable (7.41e-6)" "unprognostic (1.13e-2)" "unprognostic (8.73e-2)" "unprognostic (6.92e-2)" "unprognostic (4.32e-1)" "unprognostic (9.53e-3)" "unprognostic (6.48e-3)" "unprognostic (1.84e-3)" "unprognostic (2.86e-2)" "unprognostic (5.61e-1)" "unprognostic (2.43e-1)" "unprognostic (7.05e-2)" "unprognostic (1.32e-3)" "unprognostic (8.75e-2)" "unprognostic (2.65e-1)" "unprognostic (8.20e-2)" "unprognostic (6.54e-2)" "unprognostic (1.03e-1)" "unprognostic (2.92e-1)" "unprognostic (3.88e-2)" "unprognostic (1.68e-1)" SMG8 "C17orf71, FLJ10587, FLJ23205" ENSG00000167447 "SMG8 nonsense mediated mRNA decay factor" Q8ND04 17 59209400-59215239 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Nonsense-mediated mRNA decay" "Cataract, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 5.0;Brain excitatory neurons: 4.2;Brain inhibitory neurons: 4.3;Ependymal cells: 3.9;Foveolar cells: 3.2;Microglia: 3.6;Oligodendrocyte progenitor cells: 3.8;Oligodendrocytes: 4.9;Other brain neurons: 6.9;Smooth muscle cells: 3.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Macrophages, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024841 Approved Approved "Nucleoplasm,Vesicles,Primary cilium,Primary cilium tip,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 61: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 27: Breast cancer - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" 7 Nucleoplasm "Vesicles, Primary cilium, Primary cilium tip, Cytosol" "HPA024841: " "unprognostic (1.96e-1)" "unprognostic (1.05e-2)" "unprognostic (7.66e-2)" "unprognostic (2.89e-2)" "unprognostic (3.01e-2)" "unprognostic (1.70e-1)" "unprognostic (1.19e-2)" "unprognostic (4.12e-1)" "unprognostic (3.54e-3)" "potential prognostic favorable (1.07e-5)" "unprognostic (1.60e-2)" "unprognostic (2.33e-1)" "potential prognostic unfavorable (5.49e-4)" "unprognostic (1.26e-3)" "unprognostic (1.88e-1)" "unprognostic (6.45e-3)" "unprognostic (2.32e-1)" "unprognostic (6.08e-3)" "unprognostic (1.19e-1)" "unprognostic (8.27e-3)" "unprognostic (3.38e-2)" "unprognostic (8.58e-2)" "unprognostic (6.73e-2)" "unprognostic (1.74e-3)" "unprognostic (1.17e-1)" "unprognostic (8.34e-2)" "unprognostic (1.75e-1)" "unprognostic (3.10e-1)" "unprognostic (2.77e-1)" "unprognostic (1.04e-1)" SMG9 "C19orf61, FLJ12886" ENSG00000105771 "SMG9 nonsense mediated mRNA decay factor" Q9H0W8 19 43727983-43754962 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Nonsense-mediated mRNA decay" "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Late spermatids: 584.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041763, HPA042096, HPA066150" Uncertain Approved Vesicles,Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 67: Testis - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 4: Non-specific - Transcription" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 36 Cytosol Vesicles "HPA041763: , HPA042096: , HPA066150: " "unprognostic (1.81e-2)" "unprognostic (1.12e-1)" "unprognostic (1.54e-1)" "unprognostic (2.13e-1)" "unprognostic (2.19e-3)" "unprognostic (3.73e-1)" "unprognostic (1.99e-1)" "unprognostic (1.68e-1)" "unprognostic (1.78e-1)" "unprognostic (4.56e-2)" "unprognostic (1.14e-1)" "unprognostic (6.25e-2)" "potential prognostic unfavorable (1.65e-5)" "unprognostic (1.29e-2)" "potential prognostic unfavorable (8.39e-5)" "unprognostic (6.31e-2)" "unprognostic (1.76e-1)" "unprognostic (8.13e-3)" "unprognostic (6.61e-2)" "unprognostic (3.39e-2)" "unprognostic (2.06e-1)" "unprognostic (7.74e-3)" "unprognostic (2.05e-1)" "unprognostic (1.89e-2)" "unprognostic (1.35e-1)" "unprognostic (9.33e-3)" "unprognostic (4.68e-2)" "unprognostic (2.02e-1)" "unprognostic (1.36e-2)" "unprognostic (9.55e-3)" SMIM1 Vel ENSG00000235169 "Small integral membrane protein 1 (Vel blood group)" B2RUZ4 1 3772749-3775982 "Blood group antigen proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 47.8;testis: 47.4" "Cell type enhanced" "Detected in many" "Breast lactating cells: 74.4;Erythrocyte progenitors: 225.3;Erythrocytes: 135.9;Megakaryocyte-Erythroid progenitors: 73.0;Megakaryocytes: 537.8;Parietal cells: 74.3;Platelets: 201.8" "Cell type enhanced" "Detected in many" "oligodendrocyte: 4.1" "Cancer enhanced" "Detected in all" "Thyroid Carcinoma (TCGA): 49.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 11 "eosinophil: 48.7" "Lineage enriched" "Detected in many" 12 "granulocytes: 48.7" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Somatotropes, Skin - Eccrine sweat gland cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA069088 Enhanced NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 35: Non-specific - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 48 "HPA069088: " "unprognostic (1.82e-3)" "unprognostic (2.17e-2)" "unprognostic (3.00e-3)" "unprognostic (2.95e-2)" "unprognostic (1.46e-2)" "potential prognostic unfavorable (6.86e-4)" "unprognostic (5.55e-2)" "unprognostic (4.71e-2)" "unprognostic (6.85e-3)" "unprognostic (1.30e-1)" "unprognostic (3.95e-2)" "unprognostic (9.74e-3)" "unprognostic (2.44e-3)" "unprognostic (3.40e-1)" "unprognostic (1.64e-3)" "unprognostic (1.63e-1)" "unprognostic (4.18e-2)" "unprognostic (2.43e-1)" "unprognostic (9.27e-3)" "unprognostic (1.39e-1)" "unprognostic (9.87e-2)" "unprognostic (1.80e-1)" "unprognostic (6.65e-2)" "unprognostic (3.63e-2)" "unprognostic (8.86e-2)" "unprognostic (2.79e-2)" "unprognostic (2.67e-1)" SMIM10 CXorf69 ENSG00000184785 "Small integral membrane protein 10" Q96HG1 X 134990991-134992473 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 48.5" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 30.9;Erythrocyte progenitors: 65.4;Fallopian tube ciliated cells: 56.6;Megakaryocyte-Erythroid progenitors: 39.9;Megakaryocytes: 49.5;Melanocytes: 34.6;Pericytes: 33.3;Sertoli cells: 59.2;Smooth muscle cells: 38.1;Vascular smooth muscle cells: 61.7" "Cell type enhanced" "Detected in many" "endothelial cell: 18.0;vascular associated smooth muscle cell: 29.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 2.0;NK-cell: 3.4" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Sertoli cells" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 43: Hindbrain - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 62: Smooth muscle cells - Muscle contraction" "unprognostic (2.69e-1)" "unprognostic (5.18e-2)" "unprognostic (2.56e-3)" "unprognostic (1.36e-3)" "unprognostic (4.03e-2)" "unprognostic (4.47e-2)" "potential prognostic unfavorable (8.61e-8)" "unprognostic (3.51e-3)" "unprognostic (1.03e-3)" "potential prognostic favorable (8.18e-5)" "unprognostic (8.70e-3)" "unprognostic (4.61e-1)" "unprognostic (1.23e-2)" "unprognostic (7.71e-2)" "potential prognostic unfavorable (9.40e-4)" "unprognostic (3.61e-1)" "unprognostic (1.36e-1)" "unprognostic (3.65e-3)" "unprognostic (9.69e-2)" "unprognostic (8.68e-2)" "unprognostic (8.31e-2)" "unprognostic (2.30e-2)" "unprognostic (1.04e-1)" "unprognostic (5.56e-2)" "unprognostic (1.04e-1)" "unprognostic (3.89e-3)" "unprognostic (1.27e-1)" "unprognostic (2.47e-1)" "unprognostic (1.04e-1)" SMIM10L1 ENSG00000256537 "Small integral membrane protein 10 like 1" P0DMW3 12 11171194-11176016 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 8.3;Bergmann glia: 11.6;Brain excitatory neurons: 18.7;Brain inhibitory neurons: 17.9;Choroid plexus epithelial cells: 7.7;Distal convoluted tubule cells: 6.6;Ependymal cells: 10.1;Loop of henle epithelial cells: 6.5;Microglia: 8.7;Oligodendrocyte progenitor cells: 13.2;Oligodendrocytes: 21.3;Other brain neurons: 26.4;Podocytes: 8.5;Proximal tubule cells: 6.8;Renal collecting duct principal cells: 5.9;Renal connecting tubule cells: 6.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 98: Neurons - Neurotransmission & signaling" "unprognostic (6.13e-1)" "unprognostic (7.49e-2)" "unprognostic (3.77e-1)" "unprognostic (8.18e-3)" "unprognostic (2.51e-1)" "unprognostic (3.35e-1)" "unprognostic (2.44e-1)" "unprognostic (2.05e-2)" "unprognostic (2.64e-3)" "unprognostic (5.00e-3)" "unprognostic (5.10e-2)" "unprognostic (1.94e-1)" "unprognostic (2.35e-3)" "unprognostic (3.65e-2)" "unprognostic (2.41e-1)" "unprognostic (9.47e-2)" "unprognostic (2.45e-2)" "unprognostic (3.75e-3)" "unprognostic (2.77e-1)" "unprognostic (9.90e-2)" "unprognostic (3.35e-2)" "unprognostic (3.26e-1)" "unprognostic (2.02e-1)" "unprognostic (2.02e-1)" "unprognostic (2.51e-2)" "unprognostic (2.53e-1)" "unprognostic (2.20e-1)" "unprognostic (1.74e-1)" "unprognostic (4.34e-1)" SMIM10L2A "LED, LINC00086, LINC0086, MGC39606, NCRNA00086" ENSG00000178947 "Small integral membrane protein 10 like 2A" P0DMW4 X 135421944-135428075 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "adrenal gland: 28.8;brain: 38.6;epididymis: 13.6" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 36.9;Adrenal medulla cells: 21.3;Brain excitatory neurons: 9.9;Brain inhibitory neurons: 10.7;Breast myoepithelial cells: 8.6;Other brain neurons: 22.4;Sertoli cells: 8.7" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 22.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Kidney - Proximal tubular cells, Skeletal muscle - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in all" NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 1: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 18: Adrenal cortex cells - Steroidogensis" "unprognostic (1.92e-2)" "unprognostic (3.89e-2)" "unprognostic (6.25e-2)" "unprognostic (2.16e-1)" "unprognostic (6.52e-2)" "potential prognostic favorable (6.97e-6)" "unprognostic (1.45e-1)" "unprognostic (2.63e-3)" "unprognostic (3.23e-1)" "unprognostic (1.29e-1)" "unprognostic (3.35e-2)" "unprognostic (6.82e-3)" "unprognostic (2.29e-1)" "unprognostic (1.38e-1)" "unprognostic (1.43e-2)" "unprognostic (9.29e-2)" "unprognostic (3.22e-1)" "unprognostic (3.15e-2)" "unprognostic (7.24e-2)" SMIM10L2B "LINC00087, NCRNA00087, RP11-85L21.2" ENSG00000196972 "Small integral membrane protein 10 like 2B" P0DMW5 X 135094985-135098712 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 4 "brain: 38.2;heart muscle: 10.2" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 10.6;Brain excitatory neurons: 10.3;Brain inhibitory neurons: 10.7;Other brain neurons: 20.8;Retinal horizontal cells: 8.0;Sertoli cells: 9.3" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in many" 7 "Kidney Chromophobe (TCGA): 15.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Testis - Sertoli cells" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 98: Neurons - Neurotransmission & signaling" "unprognostic (8.51e-3)" "unprognostic (3.82e-1)" "unprognostic (4.22e-1)" "potential prognostic favorable (3.72e-4)" "unprognostic (1.91e-3)" "unprognostic (8.91e-2)" "unprognostic (1.41e-1)" "unprognostic (1.84e-2)" "unprognostic (9.21e-3)" "unprognostic (7.20e-2)" "unprognostic (2.82e-1)" "unprognostic (3.67e-2)" "unprognostic (9.28e-3)" "unprognostic (9.49e-2)" "unprognostic (9.60e-3)" SMIM11 "C21orf51, FAM165B, SMIM11A" ENSG00000205670 "Small integral membrane protein 11" P58511 21 34375480-34416961 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 1.4;Bergmann glia: 1.6;Brain excitatory neurons: 1.3;Brain inhibitory neurons: 1.1;Choroid plexus epithelial cells: 1.2;Epididymal clear cells: 2.0;Oligodendrocyte progenitor cells: 1.4;Oligodendrocytes: 1.5;Parietal cells: 1.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051321 Uncertain Approved "Focal adhesion sites" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 52: Non-specific - Cellular respiration" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 47: Leukemia - Hemostasis" "Cluster 98: Neurons - Neurotransmission & signaling" 5 "Focal adhesion sites" "HPA051321: " "unprognostic (1.76e-2)" "unprognostic (2.95e-1)" "unprognostic (5.91e-3)" "unprognostic (1.34e-2)" "unprognostic (2.66e-1)" "unprognostic (2.58e-1)" "unprognostic (2.70e-1)" "unprognostic (3.98e-2)" "unprognostic (2.62e-1)" "unprognostic (1.79e-2)" "unprognostic (1.12e-1)" "unprognostic (9.44e-2)" "unprognostic (2.35e-2)" "unprognostic (2.77e-1)" "unprognostic (1.35e-1)" "unprognostic (7.38e-3)" "unprognostic (1.56e-2)" "unprognostic (1.01e-2)" "unprognostic (1.89e-1)" "unprognostic (5.22e-2)" "unprognostic (3.26e-1)" "unprognostic (3.72e-2)" "potential prognostic favorable (3.26e-4)" "unprognostic (1.91e-2)" "unprognostic (6.30e-2)" "unprognostic (1.19e-1)" "unprognostic (7.81e-2)" "unprognostic (3.28e-2)" "unprognostic (1.15e-1)" SMIM12 "C1orf212, FLJ90372" ENSG00000163866 "Small integral membrane protein 12" Q96EX1 1 34712737-34859755 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 146.2;Pericytes: 187.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065331 Approved Approved Mitochondria NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 1: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 6 Mitochondria "HPA065331: " "unprognostic (4.05e-1)" "unprognostic (9.22e-2)" "unprognostic (4.86e-3)" "unprognostic (7.25e-3)" "unprognostic (1.62e-1)" "unprognostic (5.74e-2)" "potential prognostic favorable (3.57e-5)" "unprognostic (7.35e-2)" "potential prognostic unfavorable (7.91e-4)" "validated prognostic favorable (8.75e-9)" "validated prognostic favorable (8.03e-4)" "unprognostic (6.98e-3)" "potential prognostic unfavorable (3.16e-5)" "unprognostic (2.58e-1)" "unprognostic (8.94e-3)" "unprognostic (2.36e-1)" "unprognostic (1.70e-1)" "unprognostic (1.17e-1)" "unprognostic (2.34e-1)" "unprognostic (2.70e-2)" "unprognostic (2.22e-1)" "unprognostic (3.27e-1)" "unprognostic (1.42e-1)" "unprognostic (1.59e-2)" "unprognostic (1.40e-1)" "unprognostic (2.09e-1)" "unprognostic (8.89e-2)" "unprognostic (2.83e-1)" "unprognostic (7.22e-2)" SMIM13 C6orf228 ENSG00000224531 "Small integral membrane protein 13" P0DJ93 6 11093834-11138733 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 28.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 79.0;Syncytiotrophoblasts: 94.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065706 Enhanced Approved "Nucleoplasm,Nuclear membrane,Golgi apparatus" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 37: Neurons - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 26: Keratinocytes - Keratinization" Nucleoplasm "Nuclear membrane, Golgi apparatus" "HPA065706: " "unprognostic (5.18e-2)" "unprognostic (1.02e-1)" "unprognostic (1.04e-1)" "unprognostic (6.34e-2)" "unprognostic (8.81e-2)" "unprognostic (1.30e-1)" "unprognostic (1.54e-1)" "unprognostic (9.71e-2)" "unprognostic (8.43e-2)" "unprognostic (1.24e-2)" "unprognostic (8.33e-3)" "potential prognostic unfavorable (5.55e-4)" "unprognostic (6.32e-2)" "unprognostic (1.32e-2)" "unprognostic (1.63e-1)" "unprognostic (1.46e-1)" "unprognostic (1.06e-1)" "unprognostic (6.78e-2)" "unprognostic (1.52e-1)" "unprognostic (2.07e-1)" "unprognostic (1.55e-2)" "unprognostic (1.79e-1)" "unprognostic (8.53e-2)" "unprognostic (1.24e-1)" "unprognostic (1.02e-1)" "unprognostic (1.69e-2)" "unprognostic (1.64e-1)" "unprognostic (2.28e-2)" "unprognostic (4.74e-2)" SMIM14 "C4orf34, FLJ13289" ENSG00000163683 "Small integral membrane protein 14" Q96QK8 4 39546336-39638902 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 110.6" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 532.0;Goblet cells: 527.2;Hepatocytes: 770.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051299 Uncertain NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 27: Non-specific - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 70: Intestinal goblet cells - Mucin production" 5 "HPA051299: " "unprognostic (2.79e-3)" "unprognostic (1.93e-1)" "unprognostic (2.75e-1)" "unprognostic (7.10e-3)" "unprognostic (9.33e-2)" "unprognostic (1.53e-1)" "unprognostic (3.67e-1)" "potential prognostic favorable (3.32e-4)" "unprognostic (3.59e-2)" "potential prognostic favorable (9.97e-7)" "unprognostic (1.07e-3)" "unprognostic (5.44e-2)" "potential prognostic favorable (1.38e-4)" "unprognostic (7.91e-2)" "unprognostic (6.07e-2)" "unprognostic (8.51e-2)" "unprognostic (3.25e-2)" "unprognostic (3.01e-1)" "unprognostic (1.00e-1)" "unprognostic (1.27e-2)" "potential prognostic favorable (6.40e-4)" "unprognostic (1.83e-1)" "unprognostic (7.34e-2)" "unprognostic (1.22e-3)" "unprognostic (1.70e-1)" "unprognostic (1.13e-2)" "unprognostic (7.76e-2)" "unprognostic (8.23e-2)" "unprognostic (5.85e-3)" SMIM15 "C5orf43, DKFZP686E2158" ENSG00000188725 "Small integral membrane protein 15" Q7Z3B0 5 61157704-61162468 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 234.7;Esophageal suprabasal cells: 180.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 17: Intestine - Digestion" "Cluster 55: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 85: Squamous epithelial cells - Keratinization" "unprognostic (3.35e-2)" "unprognostic (9.93e-2)" "potential prognostic unfavorable (9.09e-5)" "unprognostic (1.35e-2)" "unprognostic (1.78e-2)" "unprognostic (1.62e-1)" "unprognostic (2.56e-3)" "unprognostic (9.72e-2)" "potential prognostic unfavorable (9.54e-4)" "potential prognostic favorable (7.98e-7)" "unprognostic (2.45e-3)" "unprognostic (1.73e-1)" "unprognostic (4.52e-2)" "validated prognostic unfavorable (2.12e-4)" "validated prognostic unfavorable (7.69e-5)" "unprognostic (6.26e-2)" "unprognostic (5.94e-2)" "unprognostic (1.23e-1)" "unprognostic (1.11e-2)" "unprognostic (3.19e-2)" "unprognostic (3.74e-1)" "unprognostic (9.93e-2)" "unprognostic (9.33e-2)" "unprognostic (9.35e-3)" "unprognostic (3.57e-2)" "unprognostic (2.24e-1)" "unprognostic (1.48e-1)" "unprognostic (1.22e-1)" "unprognostic (4.50e-1)" SMIM17 ENSG00000268182 "Small integral membrane protein 17" P0DL12 19 56643159-56657247 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "brain: 13.4" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 1.9;Loop of henle epithelial cells: 1.2;Other brain neurons: 1.0;Podocytes: 3.4;Proximal tubule cells: 2.1;Renal collecting duct intercalated cells: 1.5;Renal connecting tubule cells: 1.6" "Cell type enhanced" "Detected in single" "cerebellar inhibitory: 2.2" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA071857, HPA071861" Enhanced Approved Vesicles NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 105: Non-specific - Mixed function" Vesicles "HPA071857: , HPA071861: " "unprognostic (1.80e-1)" "unprognostic (5.76e-3)" "unprognostic (8.97e-2)" SMIM18 ENSG00000253457 "Small integral membrane protein 18" P0DKX4 8 30638580-30646064 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 6 "brain: 8.8;pituitary gland: 5.0;retina: 3.4" "Cell type enhanced" "Detected in many" "Adipocytes: 23.7;Cardiomyocytes: 12.8;Corticotrophs: 25.0;Epicardial cells: 13.6;Other brain neurons: 15.7;Retinal bipolar cells: 12.7;Retinal horizontal cells: 12.0" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in single" 6 "Glioblastoma Multiforme (TCGA): 3.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in some" 5 "Neuroblastoma: 5.6" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066648 Supported Uncertain Nucleoplasm,Centrosome NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 27: Cerebellum - Synaptic function" "Cluster 1: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 98: Neurons - Neurotransmission & signaling" Nucleoplasm Centrosome "HPA066648: " "unprognostic (1.41e-1)" "unprognostic (7.22e-2)" "potential prognostic favorable (2.82e-4)" "unprognostic (2.63e-1)" SMIM19 C8orf40 ENSG00000176209 "Small integral membrane protein 19" Q96E16 8 42541155-42555195 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011145, HPA074830" Uncertain Approved "Nuclear speckles" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 31: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 51: Secretory epithelial cells - Mixed function" 4 "Nuclear speckles" "HPA011145: , HPA074830: " "unprognostic (2.18e-1)" "unprognostic (1.32e-1)" "unprognostic (1.62e-2)" "unprognostic (2.34e-1)" "unprognostic (1.53e-1)" "potential prognostic unfavorable (9.42e-4)" "unprognostic (1.26e-1)" "unprognostic (3.75e-2)" "unprognostic (1.37e-1)" "potential prognostic favorable (2.89e-8)" "unprognostic (1.94e-3)" "unprognostic (8.91e-2)" "unprognostic (6.23e-3)" "unprognostic (9.39e-2)" "unprognostic (1.86e-1)" "unprognostic (4.58e-3)" "unprognostic (3.94e-2)" "unprognostic (1.84e-1)" "unprognostic (3.72e-2)" "unprognostic (1.23e-2)" "unprognostic (1.73e-1)" "unprognostic (2.16e-3)" "unprognostic (1.61e-1)" "unprognostic (1.96e-1)" "potential prognostic unfavorable (3.05e-4)" "unprognostic (2.36e-1)" "unprognostic (3.34e-2)" "unprognostic (4.95e-2)" "unprognostic (2.86e-2)" SMIM2 "C13orf44, MGC5590" ENSG00000139656 "Small integral membrane protein 2" Q9BVW6 13 44143150-44161257 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 22.5" "Group enriched" "Detected in some" 7 "Early spermatids: 52.9;Late primary spermatocytes: 46.9" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" "HPA026891, HPA077071" Enhanced Uncertain "Nucleoplasm,Nuclear bodies" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 53: Neurons - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" 2 "Nucleoplasm, Nuclear bodies" "HPA026891: , HPA077071: " "unprognostic (1.65e-1)" "unprognostic (1.25e-2)" "validated prognostic favorable (3.63e-5)" "validated prognostic favorable (1.11e-4)" "unprognostic (2.53e-3)" "unprognostic (5.38e-2)" "unprognostic (2.27e-1)" "unprognostic (4.61e-2)" SMIM20 "C4orf52, MITRAC7, PNX" ENSG00000250317 "Small integral membrane protein 20" Q8N5G0 4 25861830-25929813 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 221.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016552 Approved Approved Nucleoplasm,Nucleoli,Cytosol "Secreted to blood" "No annotated function" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 44: Plasma cells - Antibody production & secretion" "Nucleoplasm, Cytosol" Nucleoli "HPA016552: " "unprognostic (1.20e-1)" "unprognostic (4.86e-2)" "unprognostic (4.65e-1)" "unprognostic (2.09e-1)" "unprognostic (5.42e-2)" "validated prognostic unfavorable (9.98e-5)" "validated prognostic unfavorable (9.78e-4)" "unprognostic (6.03e-2)" "unprognostic (1.81e-1)" "unprognostic (1.33e-3)" "unprognostic (2.72e-2)" "unprognostic (1.42e-2)" "potential prognostic unfavorable (3.12e-4)" "unprognostic (1.03e-3)" "unprognostic (1.31e-1)" "unprognostic (6.04e-2)" "unprognostic (3.23e-1)" "unprognostic (2.76e-1)" "unprognostic (2.29e-1)" "unprognostic (1.92e-1)" "unprognostic (4.13e-1)" "unprognostic (1.59e-1)" "unprognostic (9.48e-2)" "unprognostic (2.98e-2)" "unprognostic (5.44e-1)" "unprognostic (8.19e-2)" "unprognostic (7.40e-2)" "unprognostic (2.88e-1)" "unprognostic (5.70e-3)" SMIM21 C18orf62 ENSG00000206026 "Small integral membrane protein 21" Q3B7S5 18 75409476-75427703 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 27 "testis: 2.6" "Group enriched" "Detected in some" 88 "Early spermatids: 76.9;Late primary spermatocytes: 43.9;Late spermatids: 70.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" HPA041686 Enhanced NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" 1 "HPA041686: " SMIM22 CASIMO1 ENSG00000267795 "Small integral membrane protein 22" K7EJ46 16 4788397-4796491 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 178.3;salivary gland: 126.4;stomach 1: 156.9" "Cell type enhanced" "Detected in many" "Colonocytes: 2039.1;Enteric transient amplifying cells: 664.4;Enterocytes: 1488.4;Foveolar cells: 1107.7;Gastric chief cells: 976.3;Goblet cells: 1211.2;Mucous neck cells: 574.3;Parietal cells: 940.5;Respiratory ciliated cells: 522.4" "Cell type enhanced" "Detected in some" "oligodendrocyte: 3.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 142.5;colorectal cancer: 173.2" "Breast - Breast glandular cells, Colon - Colon enterocytes, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Somatotropes, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA077331 Approved Nucleoplasm,Cytosol NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 60: Stomach - Digestion" "Cluster 30: White matter - Myelination" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" Nucleoplasm Cytosol "HPA077331: " "unprognostic (9.75e-2)" "unprognostic (2.78e-1)" "unprognostic (1.69e-2)" "unprognostic (1.32e-2)" "unprognostic (6.12e-3)" "unprognostic (2.66e-2)" "unprognostic (3.48e-2)" "potential prognostic unfavorable (2.69e-4)" "unprognostic (2.62e-1)" "unprognostic (6.38e-2)" "unprognostic (5.30e-3)" "unprognostic (1.44e-1)" "unprognostic (1.07e-1)" "potential prognostic unfavorable (7.70e-4)" "unprognostic (8.47e-3)" "unprognostic (4.25e-2)" "unprognostic (4.67e-1)" "unprognostic (1.08e-2)" "unprognostic (6.55e-2)" "unprognostic (2.65e-1)" "unprognostic (1.37e-1)" "potential prognostic unfavorable (7.20e-4)" "unprognostic (3.54e-1)" "unprognostic (3.14e-1)" "unprognostic (2.28e-1)" "unprognostic (1.31e-1)" SMIM23 "C5orf50, LOC644994" ENSG00000185662 "Small integral membrane protein 23" A6NLE4 5 171782432-171796126 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 197 "testis: 23.6" "Cell type enhanced" "Detected in some" "Early spermatids: 441.4;Late primary spermatocytes: 135.9;Late spermatids: 90.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 72: Neuronal - Signal transduction" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" SMIM24 "C19orf77, HSPC323" ENSG00000095932 "Small integral membrane protein 24" O75264 19 3473986-3480525 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "epididymis: 1491.1;intestine: 708.4;kidney: 785.7" "Group enriched" "Detected in many" 5 "Enterocytes: 3849.8;Epididymal efferent duct absorptive cells: 1015.5;Epididymal principal cells: 2513.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 728.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 5.9" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Gastric cancer: 35.6;Leukemia: 96.4" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Pancreas - Alpha cells, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA045046, HPA056027" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 22: Epididymis - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" Nucleoplasm Cytosol "HPA045046: , HPA056027: " "unprognostic (5.66e-3)" "unprognostic (3.00e-2)" "unprognostic (3.39e-2)" "unprognostic (2.51e-1)" "unprognostic (1.42e-1)" "unprognostic (8.57e-2)" "validated prognostic favorable (3.19e-10)" "validated prognostic favorable (3.74e-6)" "unprognostic (4.98e-2)" "unprognostic (1.38e-1)" "unprognostic (3.26e-1)" "unprognostic (3.38e-2)" "unprognostic (2.03e-2)" "unprognostic (1.28e-1)" "unprognostic (1.06e-1)" "unprognostic (2.67e-1)" "unprognostic (2.27e-1)" "unprognostic (1.93e-2)" "unprognostic (1.38e-1)" "unprognostic (3.46e-1)" "unprognostic (2.33e-1)" "unprognostic (1.84e-2)" "unprognostic (2.12e-1)" "unprognostic (2.15e-1)" "unprognostic (3.00e-1)" SMIM26 "LINC00493, LOC388789" ENSG00000232388 "Small integral membrane protein 26" A0A096LP01 20 18567347-18569563 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric chief cells: 294.9;Parietal cells: 440.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068733 Approved Nucleoplasm,Cytosol NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 62: Non-specific - Plasma proteins" "Cluster 97: Non-specific - Cellular respiration" 2 Nucleoplasm Cytosol "HPA068733: " "unprognostic (2.93e-2)" "unprognostic (2.92e-1)" "unprognostic (1.42e-3)" "unprognostic (3.94e-1)" "unprognostic (1.16e-1)" "unprognostic (1.50e-1)" "unprognostic (9.25e-2)" "unprognostic (4.16e-2)" "unprognostic (6.09e-3)" "unprognostic (2.24e-2)" "unprognostic (1.59e-1)" "unprognostic (1.35e-1)" "unprognostic (1.34e-3)" "unprognostic (1.07e-1)" "unprognostic (5.00e-2)" "unprognostic (1.47e-1)" "unprognostic (2.58e-1)" "unprognostic (4.41e-2)" "unprognostic (2.20e-2)" "unprognostic (2.66e-2)" "unprognostic (2.52e-1)" "unprognostic (1.56e-1)" "unprognostic (5.40e-2)" "unprognostic (5.30e-2)" "unprognostic (5.58e-3)" "unprognostic (7.88e-2)" "unprognostic (3.58e-2)" "unprognostic (3.83e-1)" "unprognostic (1.56e-2)" SMIM27 "C9orf133, TOPORS-AS1" ENSG00000235453 "Small integral membrane protein 27" A0A1B0GUW7 9 32551144-32568621 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 422.4;Late primary spermatocytes: 363.9;Late spermatids: 233.7;Parietal cells: 143.2;Platelets: 152.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 758.0" "Lineage enriched" "Detected in all" 5 "granulocytes: 758.0" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 7: Non-specific - Ribosome" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" "unprognostic (1.53e-3)" "unprognostic (4.66e-3)" "unprognostic (3.41e-3)" "unprognostic (1.39e-2)" "unprognostic (1.69e-1)" "unprognostic (4.80e-2)" "unprognostic (2.76e-1)" "unprognostic (1.92e-1)" "unprognostic (9.74e-2)" "unprognostic (6.03e-2)" "unprognostic (3.09e-1)" "unprognostic (1.34e-2)" "unprognostic (7.18e-2)" "unprognostic (3.06e-2)" "unprognostic (3.93e-2)" "unprognostic (5.81e-3)" "unprognostic (5.97e-2)" "unprognostic (2.86e-3)" "unprognostic (5.97e-3)" "potential prognostic favorable (6.02e-4)" "unprognostic (2.62e-2)" "unprognostic (9.43e-2)" "unprognostic (1.29e-1)" "unprognostic (7.19e-2)" "unprognostic (6.40e-3)" "unprognostic (1.29e-1)" "unprognostic (9.48e-2)" "unprognostic (2.64e-1)" "unprognostic (1.22e-1)" SMIM28 ENSG00000262543 "Small integral membrane protein 28" A0A1B0GU29 6 138377905-138383486 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 5 "intestine: 2.5" "Cell type enhanced" "Detected in some" "Pancreatic islet cells: 1.0;Prostatic glandular cells: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 22 "Neuroblastoma: 5.7;prostate cancer: 2.2" "Colon - Colon enteroendocrine cells, Prostate - Prostate glandular cells" "Not detected" "Not detected" NA NA "Cluster 77: Intestine - Digestion" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" SMIM29 "C6orf1, LBH, MGC57858" ENSG00000186577 "Small integral membrane protein 29" Q86T20 6 34246381-34249108 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 148.5" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 73.4;Esophageal basal cells: 73.7;Esophageal suprabasal cells: 86.9;Hofbauer cells: 153.2;Melanocytes: 101.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 414.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037659, HPA037660" Uncertain NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 28: Non-specific - Nuclear processes" "Cluster 61: Schwann cells & Melanocytes - Mixed function" "HPA037659: , HPA037660: " "unprognostic (3.21e-2)" "unprognostic (4.47e-1)" "unprognostic (7.03e-2)" "unprognostic (2.51e-3)" "unprognostic (9.40e-2)" "unprognostic (1.45e-1)" "unprognostic (3.41e-1)" "unprognostic (2.53e-1)" "unprognostic (2.79e-1)" "potential prognostic unfavorable (1.38e-6)" "unprognostic (4.89e-2)" "unprognostic (1.41e-1)" "potential prognostic unfavorable (1.30e-4)" "unprognostic (9.42e-3)" "unprognostic (8.85e-2)" "unprognostic (1.07e-1)" "unprognostic (2.30e-1)" "unprognostic (8.56e-2)" "unprognostic (4.83e-2)" "unprognostic (5.57e-2)" "unprognostic (3.14e-2)" "unprognostic (8.61e-2)" "unprognostic (1.23e-1)" "unprognostic (2.34e-1)" "unprognostic (2.10e-1)" "unprognostic (2.19e-2)" "unprognostic (2.78e-1)" "unprognostic (8.84e-2)" "unprognostic (5.91e-2)" SMIM3 "C5orf62, MSTP150, NID67" ENSG00000256235 "Small integral membrane protein 3" Q9BZL3 5 150778757-150796734 "Essential proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "Platelets: 914.7" "Group enriched" "Detected in many" 4 "choroid plexus epithelial cell: 40.2;endothelial cell: 78.0;fibroblast: 29.3;pericyte: 115.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA075345 Approved Vesicles NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 47: Platelets - Hemostasis" 44 Vesicles "HPA075345: " "unprognostic (3.54e-2)" "unprognostic (3.32e-1)" "unprognostic (3.03e-2)" "unprognostic (3.98e-1)" "unprognostic (1.35e-1)" "unprognostic (1.69e-2)" "unprognostic (1.16e-2)" "unprognostic (5.88e-2)" "potential prognostic unfavorable (6.47e-4)" "unprognostic (8.45e-3)" "unprognostic (2.96e-1)" "unprognostic (1.95e-3)" "unprognostic (1.49e-1)" "unprognostic (2.94e-3)" "unprognostic (1.13e-2)" "unprognostic (3.23e-3)" "unprognostic (4.30e-2)" "unprognostic (2.61e-2)" "unprognostic (1.71e-2)" "unprognostic (1.17e-1)" "unprognostic (2.92e-2)" "unprognostic (1.23e-1)" "unprognostic (3.63e-3)" "unprognostic (1.88e-2)" "unprognostic (2.17e-1)" "unprognostic (1.17e-1)" SMIM30 LINC00998 ENSG00000214194 "Small integral membrane protein 30" A4D0T7 7 113116718-113118560 "Predicted membrane proteins" "Immunity, Innate immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 246.2;Esophageal suprabasal cells: 194.3;Hofbauer cells: 353.7;Parietal cells: 281.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 21: Non-specific - Metabolism" "Cluster 39: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" "unprognostic (3.61e-2)" "unprognostic (2.89e-1)" "unprognostic (1.51e-2)" "unprognostic (1.17e-1)" "unprognostic (4.94e-3)" "unprognostic (1.32e-2)" "unprognostic (3.96e-2)" "unprognostic (7.07e-3)" "unprognostic (1.41e-1)" "unprognostic (1.10e-2)" "unprognostic (2.65e-2)" "unprognostic (2.16e-1)" "potential prognostic unfavorable (1.56e-4)" "unprognostic (2.21e-1)" "unprognostic (2.56e-1)" "unprognostic (4.73e-2)" "unprognostic (1.44e-2)" "unprognostic (6.60e-3)" "unprognostic (1.94e-2)" "unprognostic (1.50e-1)" "unprognostic (1.78e-1)" "unprognostic (3.99e-1)" "unprognostic (2.10e-1)" "unprognostic (2.12e-2)" "unprognostic (5.88e-3)" "unprognostic (5.31e-3)" "unprognostic (1.62e-1)" "unprognostic (4.35e-1)" "unprognostic (5.13e-2)" SMIM31 "h.EPR, LINC01207" ENSG00000248771 "Small integral membrane protein 31" A0A1B0GVY4 4 164754064-164803795 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "gallbladder: 7.4;intestine: 23.1;prostate: 10.3" "Cell type enhanced" "Detected in many" "Colonocytes: 151.2;Endometrial glandular cells: 48.3;Enteric stem cells: 53.6;Enteric transient amplifying cells: 61.9;Enterocytes: 202.3;Gastric progenitor cells: 107.7;Goblet cells: 178.7;Paneth cells: 77.3;Prostatic club cells: 71.7;Prostatic glandular cells: 65.5;Respiratory basal cells: 46.3;Respiratory deuterosomal cells: 66.3;Respiratory secretory cells: 116.7" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 22.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.0" "Cancer enhanced" "Detected in some" "colorectal cancer: 4.1;Gastric cancer: 6.1" "Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA "Cluster 77: Intestine - Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" "unprognostic (1.99e-1)" "unprognostic (5.99e-2)" "unprognostic (2.17e-2)" "unprognostic (3.12e-2)" "unprognostic (6.51e-2)" "unprognostic (2.51e-2)" "unprognostic (4.09e-1)" "unprognostic (2.46e-1)" "unprognostic (4.23e-2)" "unprognostic (6.15e-2)" "unprognostic (4.11e-2)" "unprognostic (2.66e-2)" "unprognostic (2.13e-1)" "unprognostic (5.08e-2)" "unprognostic (4.93e-2)" "unprognostic (1.09e-1)" "unprognostic (3.19e-2)" SMIM32 ENSG00000271824 "Small integral membrane protein 32" A0A1B0GUA5 5 136191468-136193162 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "intestine: 12.1;kidney: 47.9" "Group enriched" "Detected in some" 4 "Colonocytes: 26.1;Enteric stem cells: 16.5;Enteric transient amplifying cells: 17.5;Enterocytes: 30.6;Neuroendocrine cells: 36.3;Pancreatic islet cells: 17.1" "Cell type enhanced" "Detected in some" "deep-layer intratelencephalic: 6.9;eccentric medium spiny neuron: 5.5" "Cancer enriched" "Detected in many" 4 "Kidney Renal Papillary Cell Carcinoma (TCGA): 37.3" "Region enriched" "Detected in many" 8 "cerebral cortex: 38.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 1.9;liver cancer: 2.2;thyroid cancer: 2.6" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Pancreas - Alpha cells, Prostate - Prostate glandular cells, Skeletal muscle - Skeletal myocytes, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 33: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" "unprognostic (3.03e-1)" "unprognostic (9.03e-3)" "potential prognostic favorable (5.08e-5)" "unprognostic (2.24e-3)" "unprognostic (7.56e-2)" "potential prognostic favorable (5.35e-4)" "potential prognostic favorable (3.50e-4)" "unprognostic (8.73e-2)" "unprognostic (8.56e-3)" "unprognostic (8.76e-3)" "unprognostic (2.37e-1)" SMIM33 ENSG00000283288 "Small integral membrane protein 33" A0A1B0GW64 5 139471004-139473700 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "intestine: 3.4;salivary gland: 2.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "memory CD4 T-cell: 1.2" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 17: Intestine - Digestion" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 70: Intestinal goblet cells - Mucin production" "potential prognostic favorable (8.96e-4)" "unprognostic (3.75e-3)" SMIM34 SMIM34A ENSG00000243627 "Small integral membrane protein 34" A8MWV9 21 34418715-34423951 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 6.5" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "Kidney Chromophobe (TCGA): 2.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "lung cancer: 1.3;prostate cancer: 3.9" "Not detected" "Not detected" HPA029085 Uncertain NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 17: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "HPA029085: " "unprognostic (2.48e-2)" SMIM35 TMPRSS4-AS1 ENSG00000255274 "Small integral membrane protein 35" A0A1B0GVV1 11 118003634-118088299 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "bone marrow: 1.2;kidney: 1.1" "Cell type enhanced" "Detected in many" "Kupffer cells: 38.9;Microglia: 129.7;Papillary tip epithelial cells: 15.3;Proximal tubule cells: 22.4;Respiratory ciliated cells: 13.2" "Cell type enriched" "Detected in some" 29 "central nervous system macrophage: 122.0" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in single" "T-reg: 1.6" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Thyroid gland - T-cells" "Group enriched" "Detected in some" 5 "basal ganglia: 1.2;olfactory bulb: 3.5" "Region enriched" "Detected in some" 6 "basal ganglia: 10.4" NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 23: Choroid plexus - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" "unprognostic (8.16e-2)" "unprognostic (4.38e-2)" SMIM36 ENSG00000261873 "Small integral membrane protein 36" A0A1B0GVT2 17 55449856-55511452 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 37 "retina: 10.0;testis: 2.6" "Group enriched" "Detected in some" 6 "Retinal bipolar cells: 432.9;Rod photoreceptor cells: 507.3" "Cell type enhanced" "Detected in many" "amygdala excitatory: 22.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Group enriched" "Detected in some" 14 "midbrain: 4.0;pons: 1.6;thalamus: 4.8" NA NA "Cluster 42: Retina - Visual perception" "Cluster 51: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" SMIM38 ENSG00000284713 "Small integral membrane protein 38" A0A286YFK9 11 69155478-69162440 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 11 "stomach 1: 33.4" "Cell type enhanced" "Detected in some" "Gastric chief cells: 1.1;Parietal cells: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 4.2;lymphoma: 2.0" "Stomach - Parietal cells" "Not detected" "Not detected" NA NA "Cluster 60: Stomach - Digestion" "Cluster 37: Neurons - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 97: Non-specific - Cellular respiration" SMIM39 ENSG00000284479 "Small integral membrane protein 39" A0A1B0GW54 2 131035092-131035262 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "adipose tissue: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 24: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" SMIM4 C3orf78 ENSG00000168273 "Small integral membrane protein 4" Q8WVI0 3 52534013-52579237 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 116.7;skeletal muscle: 122.3" "Cell type enhanced" "Detected in many" "Parietal cells: 311.2;Prostatic club cells: 242.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Pituitary gland - Undifferentiated cells (Pituitary gland)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047771 Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 18: Non-specific - Translation" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 55: Non-specific - Transcription" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 97: Non-specific - Cellular respiration" "Nucleoplasm, Mitochondria" "HPA047771: " "unprognostic (2.36e-1)" "unprognostic (2.89e-2)" "unprognostic (4.80e-2)" "unprognostic (2.35e-1)" "unprognostic (1.61e-1)" "unprognostic (2.78e-2)" "unprognostic (3.20e-2)" "unprognostic (6.94e-3)" "unprognostic (2.87e-1)" "unprognostic (2.74e-1)" "unprognostic (2.49e-2)" "potential prognostic favorable (5.12e-4)" "unprognostic (3.26e-3)" "unprognostic (5.30e-3)" "unprognostic (2.63e-1)" "unprognostic (3.88e-3)" "unprognostic (7.16e-2)" "unprognostic (2.33e-2)" "unprognostic (9.56e-2)" "potential prognostic favorable (6.39e-5)" "unprognostic (4.15e-3)" "unprognostic (9.06e-2)" "unprognostic (5.72e-2)" "unprognostic (6.58e-2)" "unprognostic (8.65e-2)" "unprognostic (9.40e-2)" "unprognostic (1.17e-1)" "unprognostic (1.20e-1)" "unprognostic (1.09e-2)" SMIM40 ENSG00000286920 "Small integral membrane protein 40" Q5STR5 6 33323628-33329279 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 232 "retina: 43.4" "Cell type enriched" "Detected in some" 13 "Rod photoreceptor cells: 34.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 42: Retina - Visual perception" "Cluster 79: Photoreceptor cells - Phototransduction" SMIM41 ENSG00000284791 "Small integral membrane protein 41" A0A2R8YCJ5 12 52079704-52108255 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lung: 18.9;prostate: 6.7" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 10.3;Endometrial glandular cells: 6.5;Leydig cells: 20.0;Paneth cells: 7.7;Peritubular myoid cells: 41.3;Renal collecting duct intercalated cells: 13.1;Renal collecting duct principal cells: 10.0;Retinal bipolar cells: 6.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Stomach Adenocarcinoma (TCGA): 1.7" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 59 "plasmacytoid DC: 5.8" "Lineage enriched" "Detected in single" 59 "dendritic cells: 5.8" "Not detected" "Not detected" "Prostate - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in single" NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 13: Lung - Secretion" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 94: Gonadal somatic cells - Mixed function" "unprognostic (4.62e-1)" "unprognostic (2.72e-3)" "unprognostic (1.35e-1)" "unprognostic (8.11e-2)" "unprognostic (1.10e-1)" "unprognostic (1.56e-3)" SMIM42 ENSG00000288460 "Small integral membrane protein 42" A0A5F9ZH02 1 158127287-158128301 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 87 "testis: 8.6" "Group enriched" "Detected in some" 9 "Early spermatids: 26.4;Late primary spermatocytes: 57.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 15: Kidney cancer - Membrane components" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" SMIM43 ENSG00000164112 "Small integral membrane protein 43" Q4W5P6 4 121758881-121765427 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 13 "brain: 10.1" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 8.9;Brain inhibitory neurons: 2.1;Cytotrophoblasts: 22.6;Migrating cytotrophoblasts: 4.5;Schwann cells: 2.6;Syncytiotrophoblasts: 5.9" "Cell type enriched" "Detected in many" 5 "deep-layer near-projecting: 177.8" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebral cortex: 26.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Rhabdoid: 1.7" "Colon - Enteric glia cells" "Region enhanced" "Detected in many" "cerebral cortex: 24.8" "Group enriched" "Detected in many" 14 "cerebral cortex: 32.6;hippocampal formation: 26.3" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" "unprognostic (3.18e-1)" SMIM44 ENSG00000284638 "Small integral membrane protein 44" A0A286YF18 19 3482110-3483441 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Group enriched" "Detected in some" 5 "intestine: 12.7;retina: 16.5" "Cell type enhanced" "Detected in some" "Colonocytes: 1.5;Cone photoreceptor cells: 2.1;Enteric transient amplifying cells: 1.6;Enterocytes: 6.0;Epididymal clear cells: 6.1;Epididymal principal cells: 7.3;Foveolar cells: 4.3;Goblet cells: 1.9;Mucous neck cells: 1.6;Parietal cells: 1.8;Retinal pigment epithelial cells: 4.3;Rod photoreceptor cells: 3.8" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Colon Adenocarcinoma (TCGA): 3.4;Kidney Chromophobe (TCGA): 2.8;Pancreatic Adenocarcinoma (TCGA): 1.7;Rectum Adenocarcinoma (TCGA): 3.0;Stomach Adenocarcinoma (TCGA): 2.8" "Region enriched" "Detected in single" 5 "choroid plexus: 4.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "colorectal cancer: 1.4" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Not detected" "Not detected" NA NA "Cluster 42: Retina - Visual perception" "Cluster 36: Choroid plexus - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" "unprognostic (2.59e-2)" "unprognostic (2.18e-1)" "unprognostic (4.44e-1)" "unprognostic (1.96e-1)" "unprognostic (1.44e-3)" "unprognostic (5.51e-2)" "unprognostic (5.65e-2)" SMIM45 LINC00634 ENSG00000205704 "Small integral membrane protein 45" 22 41952150-41958939 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 15 "brain: 39.0" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 10.6;Astrocytes: 8.9;Bergmann glia: 7.9;Brain excitatory neurons: 8.1;Brain inhibitory neurons: 10.2;Early spermatids: 10.7;Late primary spermatocytes: 17.2;Oligodendrocyte progenitor cells: 8.3;Other brain neurons: 10.4;Retinal bipolar cells: 13.1;Retinal horizontal cells: 10.0" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in some" 8 "Glioblastoma Multiforme (TCGA): 10.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 2.8" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "unprognostic (1.04e-3)" "unprognostic (9.89e-2)" "unprognostic (5.35e-3)" "unprognostic (1.81e-1)" SMIM46 ENSG00000289762 "Small integral membrane protein 46" 19 14112324-14112476 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 6 "lymphoid tissue: 10.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "breast cancer: 1.2" "Low region specificity" "Detected in single" NA NA "Cluster 66: Lymphoid tissue - Immune response" "Cluster 37: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" SMIM5 C17orf109 ENSG00000204323 "Small integral membrane protein 5" Q71RC9 17 75633434-75641404 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 32.7" "Group enriched" "Detected in many" 4 "Esophageal apical cells: 1336.4;Platelets: 416.9" "Group enriched" "Detected in some" 4 "choroid plexus epithelial cell: 23.3;ependymal cell: 32.8;oligodendrocyte: 27.4" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 61.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 56 "plasmacytoid DC: 207.9" "Lineage enriched" "Detected in many" 56 "dendritic cells: 207.9" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary gland basal cells, Stomach - Gastric mucous cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA065332, HPA071268" Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 84: Apical squamous epithelium - Cornification" 7 Vesicles "Golgi apparatus" "HPA065332: , HPA071268: " "unprognostic (9.95e-3)" "unprognostic (1.17e-1)" "unprognostic (1.75e-2)" "unprognostic (7.67e-2)" "unprognostic (8.60e-2)" "unprognostic (2.50e-1)" "unprognostic (1.11e-1)" "potential prognostic favorable (3.55e-4)" "unprognostic (4.84e-1)" "unprognostic (2.89e-1)" "unprognostic (1.52e-3)" "unprognostic (3.02e-3)" "potential prognostic favorable (6.24e-4)" "unprognostic (2.37e-1)" "unprognostic (1.38e-1)" "unprognostic (3.07e-2)" "unprognostic (9.03e-2)" "unprognostic (1.36e-2)" "unprognostic (1.54e-1)" "unprognostic (5.86e-2)" "unprognostic (4.00e-2)" "unprognostic (2.36e-1)" "unprognostic (1.67e-1)" "unprognostic (1.53e-1)" "unprognostic (1.62e-1)" "unprognostic (7.36e-3)" SMIM6 "C17orf110, ELN" ENSG00000259120 "Small integral membrane protein 6" P0DI80 17 75646243-75647975 "Predicted membrane proteins, Transporters" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "fallopian tube: 22.7;kidney: 21.7;stomach 1: 31.3;testis: 25.1" "Group enriched" "Detected in many" 6 "Early spermatids: 659.2;Late spermatids: 1695.6" "Cell type enriched" "Detected in some" 6 "oligodendrocyte: 7.9" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 31.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 42 "plasmacytoid DC: 34.2" "Lineage enriched" "Detected in single" 42 "dendritic cells: 34.2" "Cancer enhanced" "Detected in many" "Gastric cancer: 9.2;Kidney cancer: 9.2" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Kidney - Intercalated cells, Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells, Testis - Late spermatids" HPA065721 Uncertain Approved Nucleoplasm Yes NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" Nucleoplasm "HPA065721: " "unprognostic (1.68e-1)" "unprognostic (5.40e-3)" "unprognostic (1.07e-2)" "unprognostic (1.51e-1)" "unprognostic (8.81e-3)" "unprognostic (7.59e-2)" "unprognostic (9.08e-2)" "unprognostic (9.42e-2)" "unprognostic (4.98e-2)" "unprognostic (1.04e-1)" "unprognostic (7.79e-2)" "unprognostic (1.33e-1)" "unprognostic (1.22e-1)" "unprognostic (4.13e-2)" "unprognostic (1.24e-1)" "unprognostic (9.90e-2)" "unprognostic (9.02e-2)" "unprognostic (3.44e-1)" "unprognostic (3.42e-3)" SMIM7 "C19orf42, MGC2747" ENSG00000214046 "Small integral membrane protein 7" Q9BQ49 19 16630751-16660442 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 44.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043127 Uncertain Approved "Golgi apparatus" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 76: Non-specific - Metabolism" "Cluster 27: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 67: Plasma cells - Plasma cell differentiation" "Golgi apparatus" "HPA043127: " "unprognostic (6.50e-2)" "unprognostic (3.20e-1)" "unprognostic (1.40e-3)" "unprognostic (2.44e-1)" "unprognostic (4.31e-2)" "unprognostic (2.91e-1)" "unprognostic (1.58e-2)" "unprognostic (3.00e-2)" "unprognostic (1.88e-1)" "potential prognostic favorable (3.44e-8)" "unprognostic (5.08e-2)" "unprognostic (1.34e-1)" "unprognostic (9.18e-2)" "unprognostic (4.51e-2)" "unprognostic (2.52e-1)" "unprognostic (1.76e-2)" "unprognostic (6.13e-2)" "unprognostic (1.50e-1)" "unprognostic (1.01e-1)" "unprognostic (2.51e-2)" "unprognostic (1.30e-1)" "unprognostic (7.22e-2)" "unprognostic (8.97e-2)" "unprognostic (3.77e-2)" "potential prognostic unfavorable (7.20e-4)" "unprognostic (2.80e-2)" "unprognostic (2.46e-1)" "unprognostic (2.26e-2)" "unprognostic (2.36e-1)" SMIM8 "C6orf162, dJ102H19.2, DKFZP586E1923" ENSG00000111850 "Small integral membrane protein 8" Q96KF7 6 87322583-87399749 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Choroid plexus epithelial cells: 149.5;Myonuclei: 150.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007401, HPA067453" Approved Approved Vesicles NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 11 Vesicles "HPA007401: , HPA067453: " "unprognostic (1.98e-2)" "unprognostic (7.23e-3)" "unprognostic (3.57e-2)" "unprognostic (2.37e-2)" "unprognostic (3.00e-2)" "unprognostic (2.91e-2)" "unprognostic (1.77e-1)" "unprognostic (1.20e-2)" "unprognostic (9.80e-2)" "validated prognostic favorable (7.55e-4)" "validated prognostic favorable (3.88e-4)" "unprognostic (4.77e-3)" "unprognostic (3.32e-2)" "unprognostic (4.11e-1)" "unprognostic (3.03e-2)" "unprognostic (8.71e-2)" "unprognostic (1.43e-2)" "unprognostic (1.56e-2)" "unprognostic (4.68e-2)" "unprognostic (3.53e-3)" "unprognostic (5.88e-3)" "unprognostic (3.59e-1)" "unprognostic (6.07e-2)" "unprognostic (3.43e-1)" "unprognostic (7.63e-2)" "unprognostic (2.76e-1)" "unprognostic (1.64e-1)" "unprognostic (8.87e-2)" "unprognostic (1.51e-1)" SMIM9 CXorf68 ENSG00000203870 "Small integral membrane protein 9" A6NGZ8 X 154823348-154834662 "Predicted membrane proteins" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Early spermatids: 28.4;Late primary spermatocytes: 25.3;Late spermatids: 12.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA060970 Uncertain NA NA "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" "HPA060970: " SMKR1 ENSG00000240204 "Small lysine rich protein 1" H3BMG3 7 129502531-129512918 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 12 "testis: 130.6" "Cell type enriched" "Detected in many" 4 "Late spermatids: 10428.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Lung - Respiratory ciliated cells, Testis - Late spermatids" "Low region specificity" "Detected in all" HPA078358 Approved Nucleoli NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 79: Testis - Spermatogenesis" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" Nucleoli "HPA078358: " "unprognostic (2.08e-1)" "unprognostic (1.55e-1)" "unprognostic (5.36e-2)" "unprognostic (3.33e-1)" "unprognostic (4.61e-2)" "validated prognostic unfavorable (4.60e-4)" "validated prognostic unfavorable (5.40e-4)" "unprognostic (2.17e-1)" "unprognostic (4.54e-3)" "potential prognostic unfavorable (2.38e-5)" "unprognostic (1.22e-1)" "unprognostic (6.31e-2)" "unprognostic (1.05e-1)" "unprognostic (4.00e-3)" "unprognostic (7.30e-2)" "unprognostic (4.90e-2)" "unprognostic (2.36e-1)" "unprognostic (8.53e-2)" "unprognostic (5.44e-2)" "unprognostic (9.37e-2)" "unprognostic (7.89e-2)" "unprognostic (1.67e-1)" "unprognostic (1.63e-2)" "unprognostic (9.33e-2)" "unprognostic (8.33e-2)" "unprognostic (1.07e-1)" SMLR1 ENSG00000256162 "Small leucine rich protein 1" H3BR10 6 130827406-130837135 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 52.9" "Group enriched" "Detected in some" 22 "Enterocytes: 154.7;Hepatocytes: 289.1" "Cell type enhanced" "Detected in single" "central nervous system macrophage: 1.1" "Cancer enriched" "Detected in some" 13 "Liver Hepatocellular Carcinoma (TCGA): 19.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 19 "liver cancer: 6.0" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA066060 Uncertain NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 53: Neurons - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 93: Hepatocytes - Bile production & excretion" "HPA066060: " "unprognostic (8.67e-3)" "unprognostic (1.56e-1)" SMN1 "BCD541, GEMIN1, SMA, SMA@, SMA1, SMA2, SMA3, SMNT, TDRD16A" ENSG00000172062 "Survival of motor neuron 1, telomeric" Q16637 5 70925030-70953942 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing, Neurogenesis" RNA-binding "Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 16.9;Late primary spermatocytes: 15.1;Late spermatids: 17.0;Megakaryocytes: 12.4;Oocytes: 9.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "CAB016324, HPA045271, CAB069888, HPA073601" Supported Supported "Nuclear bodies,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 64: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 184 "Nuclear bodies, Cytosol" "CAB016324: , CAB069888: , HPA045271: , HPA073601: " "unprognostic (5.26e-2)" "unprognostic (4.08e-2)" "unprognostic (3.19e-1)" "unprognostic (3.92e-2)" "unprognostic (2.15e-1)" "unprognostic (1.15e-2)" "unprognostic (3.75e-1)" "potential prognostic unfavorable (1.52e-4)" "unprognostic (8.44e-2)" "unprognostic (7.66e-2)" "unprognostic (4.66e-3)" "unprognostic (1.52e-1)" "unprognostic (5.14e-2)" "unprognostic (2.31e-2)" "unprognostic (5.58e-3)" "unprognostic (1.99e-2)" "unprognostic (9.60e-3)" "unprognostic (4.02e-2)" "unprognostic (1.79e-1)" "unprognostic (6.93e-2)" "unprognostic (9.63e-2)" "unprognostic (1.89e-1)" "potential prognostic unfavorable (7.63e-4)" "unprognostic (1.05e-1)" "unprognostic (3.16e-1)" "unprognostic (6.75e-3)" "unprognostic (9.03e-2)" "unprognostic (2.44e-1)" "unprognostic (3.01e-2)" "unprognostic (6.69e-3)" "unprognostic (4.22e-2)" SMN2 "BCD541, GEMIN1, SMNC, TDRD16B" ENSG00000205571 "Survival of motor neuron 2, centromeric" Q16637 5 70049638-70078522 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing, Neurogenesis" RNA-binding "Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 7.7;Bergmann glia: 12.0;Brain excitatory neurons: 10.5;Brain inhibitory neurons: 8.7;Choroid plexus epithelial cells: 7.5;Early spermatids: 13.7;Ependymal cells: 7.4;Late primary spermatocytes: 8.8;Late spermatids: 9.5;Microglia: 7.5;Oligodendrocyte progenitor cells: 8.2;Oligodendrocytes: 8.2;Other brain neurons: 8.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "CAB009344, HPA045271, HPA073601" Supported Supported "Nuclear bodies,Cytosol" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 74: Non-specific - Signal transduction" "Cluster 27: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 98: Neurons - Neurotransmission & signaling" 86 "Nuclear bodies, Cytosol" "CAB009344: , HPA045271: , HPA073601: " "unprognostic (1.68e-1)" "unprognostic (2.71e-1)" "unprognostic (1.25e-2)" "potential prognostic favorable (7.02e-4)" "unprognostic (3.02e-2)" "unprognostic (2.65e-1)" "unprognostic (1.84e-1)" "unprognostic (9.87e-2)" "unprognostic (3.11e-1)" "unprognostic (8.62e-2)" "unprognostic (2.53e-1)" "unprognostic (2.02e-1)" "unprognostic (1.71e-1)" "unprognostic (1.39e-3)" "unprognostic (5.58e-3)" "unprognostic (1.17e-1)" "unprognostic (8.50e-2)" "unprognostic (1.96e-1)" "unprognostic (3.06e-1)" "unprognostic (2.76e-1)" "unprognostic (5.85e-2)" "unprognostic (1.55e-1)" "potential prognostic unfavorable (2.50e-5)" "unprognostic (7.77e-2)" "unprognostic (2.08e-1)" "unprognostic (6.85e-2)" "unprognostic (3.07e-2)" "unprognostic (2.96e-1)" "unprognostic (1.84e-1)" "unprognostic (1.62e-1)" "unprognostic (9.97e-2)" SMNDC1 "SMNR, SPF30, TDRD16C" ENSG00000119953 "Survival motor neuron domain containing 1" O75940 10 110290730-110304938 "Essential proteins, Predicted intracellular proteins" "Apoptosis, mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA061214, HPA070666" Enhanced "Nucleoplasm,Nuclear bodies" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 17: Non-specific - RNA processing" 48 Nucleoplasm "Nuclear bodies" "HPA061214: , HPA070666: " "unprognostic (3.33e-1)" "unprognostic (3.29e-2)" "unprognostic (2.62e-1)" "unprognostic (3.31e-1)" "unprognostic (9.23e-2)" "unprognostic (1.65e-2)" "unprognostic (3.45e-2)" "unprognostic (5.98e-3)" "unprognostic (1.90e-2)" "potential prognostic unfavorable (7.85e-4)" "potential prognostic favorable (9.80e-6)" "unprognostic (3.08e-2)" "unprognostic (1.19e-2)" "potential prognostic unfavorable (4.28e-4)" "unprognostic (7.08e-3)" "unprognostic (2.71e-3)" "unprognostic (3.00e-3)" "unprognostic (2.65e-1)" "unprognostic (3.17e-1)" "unprognostic (7.18e-2)" "potential prognostic unfavorable (8.51e-4)" "unprognostic (1.64e-3)" "potential prognostic unfavorable (4.32e-4)" "unprognostic (2.42e-3)" "unprognostic (1.48e-1)" "unprognostic (8.23e-2)" "unprognostic (8.53e-3)" "unprognostic (2.92e-1)" "unprognostic (3.56e-1)" "unprognostic (1.05e-1)" "unprognostic (7.52e-2)" SMO "FZD11, SMOH" ENSG00000128602 "Smoothened, frizzled class receptor" Q99835 7 129188633-129213545 "Cancer-related genes, Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Plasma proteins, Predicted membrane proteins, Transporters" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 41.8;Bergmann glia: 41.9;Choroid plexus epithelial cells: 38.9;Ependymal cells: 38.0;Lactotrophs: 33.7;Leydig cells: 39.5;Peritubular myoid cells: 43.8;Pituitary stem cells: 49.1;Podocytes: 37.4;Proximal tubule cells: 37.8;Somatotrophs: 36.1;Thyrotrophs: 41.7" "Group enriched" "Detected in many" 4 "astrocyte: 55.6;Bergmann glia: 40.6;choroid plexus epithelial cell: 29.2;ependymal cell: 44.3;fibroblast: 22.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Liver - Hepatocytes, Lung - Fibroblasts_2, Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011446, CAB080590" Approved Supported "Golgi apparatus,Plasma membrane,Primary cilium" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 5: Rhabdoid - Unknown function" "Cluster 94: Gonadal somatic cells - Mixed function" 3 "Golgi apparatus, Plasma membrane, Primary cilium" "CAB011446: , CAB080590: " "unprognostic (2.73e-1)" "unprognostic (3.93e-2)" "unprognostic (5.42e-2)" "unprognostic (5.91e-2)" "unprognostic (3.34e-2)" "unprognostic (2.98e-1)" "unprognostic (1.28e-1)" "unprognostic (2.09e-3)" "unprognostic (2.43e-1)" "unprognostic (1.15e-1)" "unprognostic (2.32e-2)" "unprognostic (7.30e-2)" "unprognostic (6.60e-2)" "unprognostic (2.58e-1)" "unprognostic (4.01e-2)" "unprognostic (1.13e-2)" "unprognostic (1.69e-2)" "unprognostic (2.20e-1)" "unprognostic (7.14e-3)" "unprognostic (2.25e-1)" "unprognostic (1.59e-1)" "unprognostic (1.86e-2)" "unprognostic (2.44e-1)" "unprognostic (3.36e-2)" "unprognostic (1.59e-1)" "unprognostic (1.09e-1)" "potential prognostic unfavorable (9.61e-5)" "unprognostic (1.48e-3)" "unprognostic (5.21e-2)" "unprognostic (1.06e-1)" "unprognostic (2.76e-1)" SMOC1 ENSG00000198732 "SPARC related modular calcium binding 1" Q9H4F8 14 69854131-70032366 "Disease related genes, Human disease related genes, Predicted secreted proteins" Differentiation "Developmental protein" "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 62.5;liver: 58.0" "Cell type enhanced" "Detected in many" "Ependymal cells: 441.8;Hepatocytes: 205.4;Oligodendrocyte progenitor cells: 747.0;Oligodendrocytes: 310.2;Pancreatic acinar cells: 202.4;Pancreatic islet cells: 206.9;Peritubular myoid cells: 230.3;Sertoli cells: 278.8" "Group enriched" "Detected in many" 5 "committed oligodendrocyte precursor: 1125.6;ependymal cell: 460.0;oligodendrocyte precursor cell: 842.9" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 53.2;Kidney Chromophobe (TCGA): 51.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 11 "plasmacytoid DC: 1.3" "Lineage enriched" "Detected in single" 14 "dendritic cells: 1.3" "Cancer enhanced" "Detected in many" "cervical cancer: 36.1" "Adrenal gland - Adrenal medulla cells, Prostate - Fibroblasts, Skin - Outer root sheath cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004153, CAB034427" Approved Uncertain "Plasma membrane" "Secreted to extracellular matrix" "Developmental protein" NA NA 1800000 "Cluster 36: Brain & Liver - Signaling" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 7: Liver cancer - Metabolism" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 4 "Plasma membrane" "CAB034427: , HPA004153: " "unprognostic (1.92e-3)" "unprognostic (4.56e-1)" "unprognostic (1.77e-1)" "unprognostic (1.26e-2)" "unprognostic (3.13e-1)" "unprognostic (1.58e-2)" "unprognostic (1.73e-2)" "potential prognostic favorable (4.07e-4)" "unprognostic (2.79e-1)" "unprognostic (1.70e-1)" "unprognostic (5.27e-2)" "unprognostic (7.79e-2)" "unprognostic (1.87e-1)" "unprognostic (6.44e-3)" "unprognostic (1.39e-2)" "unprognostic (1.75e-3)" "unprognostic (6.99e-2)" "unprognostic (4.26e-2)" "unprognostic (2.00e-1)" "unprognostic (1.22e-1)" "potential prognostic unfavorable (1.73e-4)" "unprognostic (9.71e-2)" "unprognostic (1.64e-1)" "unprognostic (3.06e-2)" "unprognostic (1.75e-1)" "unprognostic (1.86e-1)" "unprognostic (3.27e-2)" "unprognostic (2.44e-2)" SMOC2 SMAP2 ENSG00000112562 "SPARC related modular calcium binding 2" Q9H3U7 6 168441151-168673445 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 407.9" "Cell type enhanced" "Detected in many" "Enteric stem cells: 429.3;Fibro-adipogenic progenitors: 881.6;Leydig cells: 766.0;Mesothelial cells: 301.8;Paneth cells: 611.0;Peritubular myoid cells: 1219.1;Retinal pigment epithelial cells: 196.1;Smooth muscle cells: 242.7" "Cell type enhanced" "Detected in many" "pericyte: 448.8;vascular associated smooth muscle cell: 210.0" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 7 "choroid plexus: 76.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 19.0" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Fibroblasts, Breast - Fibroblasts, Kidney - Fibroblasts, Pancreas - Fibroblasts, Skeletal muscle - Fibroblasts, Spleen - Smooth muscle cells" "Region enhanced" "Detected in many" "hippocampal formation: 25.7" "Region enhanced" "Detected in some" "spinal cord: 2.3" "Secreted to extracellular matrix" "No annotated function" NA NA 330000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 70: DU4475 - Unknown function" "Cluster 94: Gonadal somatic cells - Mixed function" 1 "potential prognostic favorable (1.27e-4)" "unprognostic (4.93e-2)" "unprognostic (2.22e-1)" "unprognostic (2.52e-2)" "unprognostic (2.19e-2)" "unprognostic (8.61e-2)" "unprognostic (1.97e-2)" "unprognostic (9.68e-2)" "unprognostic (1.19e-1)" "unprognostic (6.79e-2)" "unprognostic (1.01e-1)" "unprognostic (1.57e-3)" "potential prognostic unfavorable (1.25e-4)" "unprognostic (1.86e-1)" "unprognostic (8.80e-3)" "unprognostic (3.70e-2)" "unprognostic (1.06e-2)" "unprognostic (8.52e-2)" "unprognostic (2.31e-1)" "unprognostic (1.85e-2)" "unprognostic (2.02e-3)" "unprognostic (3.43e-1)" "potential prognostic favorable (7.69e-4)" "unprognostic (1.17e-1)" "unprognostic (9.24e-2)" "unprognostic (2.17e-1)" "unprognostic (2.27e-1)" "unprognostic (5.93e-2)" "unprognostic (2.08e-1)" "unprognostic (4.46e-2)" "unprognostic (2.75e-1)" SMOX "C20orf16, dJ779E11.1, FLJ20746, MGC1010, PAO, PAOh1, SMO" ENSG00000088826 "Spermine oxidase" Q9NWM0 20 4120980-4187747 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 62.6" "Cell type enriched" "Detected in many" 5 "Platelets: 917.1" "Cell type enhanced" "Detected in many" "astrocyte: 91.6;Bergmann glia: 44.0" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 83.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 1.0;myeloid DC: 2.4;neutrophil: 3.6;plasmacytoid DC: 1.1" "Group enriched" "Detected in many" 6 "dendritic cells: 2.4;granulocytes: 3.6;monocytes: 1.0" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047117, HPA060198" Approved Supported "Nucleoplasm,Nuclear membrane,Vesicles,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 47: Platelets - Hemostasis" Nucleoplasm "Nuclear membrane, Vesicles, Cytosol" "HPA047117: , HPA060198: " "unprognostic (5.25e-3)" "unprognostic (4.04e-2)" "unprognostic (2.11e-2)" "unprognostic (1.41e-3)" "unprognostic (6.70e-2)" "unprognostic (1.33e-1)" "unprognostic (1.36e-1)" "unprognostic (5.71e-2)" "unprognostic (1.35e-1)" "unprognostic (1.92e-1)" "unprognostic (1.22e-2)" "unprognostic (5.25e-2)" "unprognostic (7.40e-2)" "validated prognostic unfavorable (1.69e-7)" "validated prognostic unfavorable (2.26e-4)" "potential prognostic unfavorable (2.32e-4)" "unprognostic (3.09e-2)" "unprognostic (2.97e-2)" "unprognostic (1.31e-1)" "unprognostic (8.87e-2)" "unprognostic (2.92e-1)" "unprognostic (1.15e-2)" "unprognostic (1.94e-1)" "unprognostic (2.11e-1)" "unprognostic (2.18e-1)" "unprognostic (1.32e-1)" "unprognostic (7.15e-2)" "unprognostic (1.13e-1)" "unprognostic (2.01e-3)" "unprognostic (6.09e-2)" "unprognostic (1.02e-1)" SMPD1 ASM ENSG00000166311 "Sphingomyelin phosphodiesterase 1" P17405 11 6390440-6394998 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction, Lipid metabolism" "Glycosidase, Hydrolase" "Disease variant, Neurodegeneration, Niemann-Pick disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 78.8;Esophageal apical cells: 126.8;Hepatocytes: 83.9;Late spermatids: 365.5;Platelets: 132.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular), Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" Enzyme NA NA 630000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 70: Non-specific - Protein processing" "Cluster 45: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 1 "unprognostic (6.83e-2)" "unprognostic (6.12e-2)" "unprognostic (3.70e-1)" "unprognostic (2.61e-1)" "unprognostic (2.58e-1)" "unprognostic (2.79e-1)" "unprognostic (2.68e-3)" "unprognostic (2.72e-3)" "unprognostic (2.44e-1)" "unprognostic (8.07e-2)" "unprognostic (3.53e-2)" "unprognostic (5.25e-3)" "potential prognostic favorable (1.02e-4)" "unprognostic (3.16e-2)" "unprognostic (1.22e-2)" "unprognostic (3.08e-1)" "unprognostic (1.59e-1)" "unprognostic (3.28e-2)" "unprognostic (5.05e-2)" "unprognostic (2.45e-1)" "unprognostic (4.38e-1)" "unprognostic (1.20e-3)" "unprognostic (1.87e-1)" "unprognostic (5.47e-2)" "unprognostic (9.13e-2)" "unprognostic (1.84e-1)" "unprognostic (2.87e-1)" "unprognostic (1.12e-2)" "unprognostic (1.60e-1)" "unprognostic (8.03e-2)" "unprognostic (2.85e-2)" SMPD2 "ISC1, nSMase" ENSG00000135587 "Sphingomyelin phosphodiesterase 2" O60906 6 109440724-109443919 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 49.6" "Cell type enhanced" "Detected in many" "Early spermatids: 171.5;Esophageal apical cells: 74.0;Esophageal suprabasal cells: 65.8;Fallopian tube ciliated cells: 101.2;Late primary spermatocytes: 208.5;Late spermatids: 566.5;Respiratory ciliated cells: 78.9" "Cell type enhanced" "Detected in many" "ependymal cell: 19.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018110, HPA018125" Uncertain Approved "Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 28: Non-specific - Nuclear processes" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 30 "Vesicles, Plasma membrane" "Cell Junctions" "HPA018110: , HPA018125: " "unprognostic (2.48e-1)" "unprognostic (4.68e-2)" "unprognostic (2.92e-1)" "unprognostic (7.53e-2)" "unprognostic (9.66e-2)" "unprognostic (2.08e-1)" "unprognostic (6.66e-2)" "unprognostic (1.93e-1)" "unprognostic (3.29e-1)" "unprognostic (1.05e-1)" "unprognostic (1.57e-2)" "unprognostic (7.38e-2)" "unprognostic (8.71e-3)" "validated prognostic unfavorable (2.67e-6)" "validated prognostic unfavorable (1.70e-4)" "unprognostic (6.51e-2)" "unprognostic (2.88e-1)" "unprognostic (2.01e-1)" "unprognostic (5.50e-2)" "unprognostic (5.79e-2)" "unprognostic (2.29e-2)" "potential prognostic favorable (1.54e-4)" "unprognostic (2.08e-1)" "unprognostic (1.34e-1)" "unprognostic (3.39e-2)" "unprognostic (1.32e-2)" "unprognostic (2.41e-1)" "unprognostic (3.84e-1)" "unprognostic (4.79e-2)" "unprognostic (6.05e-2)" "unprognostic (1.44e-1)" SMPD3 NSMASE2 ENSG00000103056 "Sphingomyelin phosphodiesterase 3" Q9NY59 16 68358327-68448508 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Lipid metabolism, Sphingolipid metabolism" "Developmental protein, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 57.9;lymphoid tissue: 48.4" "Cell type enhanced" "Detected in many" "Enterocytes: 153.8;Epicardial cells: 152.4;Lactotrophs: 78.6;Mesothelial cells: 90.8;Neuroendocrine cells: 76.9;pDCs: 218.4;Retinal bipolar cells: 144.4;Retinal horizontal cells: 514.9;Thyrotrophs: 83.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "plasmacytoid DC: 139.0" "Lineage enriched" "Detected in many" 7 "dendritic cells: 139.0" "Cancer enhanced" "Detected in many" "Leukemia: 11.1;lymphoma: 12.1;Neuroblastoma: 11.2" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Breast - Breast glandular cells, Skin - Keratinocyte (granular), Stomach - Gastric mucous cells" "Region enhanced" "Detected in all" "basal ganglia: 115.2" "Region enhanced" "Detected in all" "basal ganglia: 83.7" "CAB033885, HPA065535, HPA069383" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 51: Neurons - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 109: Neurons - Neuronal signaling" 2 "Endoplasmic reticulum" "CAB033885: , HPA065535: , HPA069383: " "unprognostic (1.74e-1)" "unprognostic (2.12e-1)" "unprognostic (3.71e-1)" "unprognostic (1.40e-2)" "unprognostic (7.77e-2)" "unprognostic (1.50e-1)" "unprognostic (1.34e-1)" "potential prognostic favorable (7.09e-6)" "unprognostic (2.12e-3)" "unprognostic (3.78e-3)" "unprognostic (8.03e-2)" "unprognostic (2.54e-2)" "unprognostic (3.16e-1)" "unprognostic (3.74e-1)" "unprognostic (6.80e-2)" "unprognostic (5.98e-2)" "unprognostic (6.50e-2)" "unprognostic (1.64e-2)" "potential prognostic unfavorable (4.18e-4)" "unprognostic (4.92e-2)" "unprognostic (1.92e-2)" "unprognostic (1.79e-1)" "unprognostic (6.84e-2)" SMPD4 "FLJ20297, FLJ20756, KIAA1418, NET13, nSMase-3, NSMASE3" ENSG00000136699 "Sphingomyelin phosphodiesterase 4" Q9NXE4 2 130151392-130182750 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Pituitary gland - Somatotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046279, HPA049426" Approved Approved "Nuclear membrane,Cytosol" NA Yes "Cluster 33: Non-specific - ATP binding" "Cluster 39: Testis - Nuclear processes" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 44: Plasma cells - Antibody production & secretion" 6 "Nuclear membrane" Cytosol "HPA046279: , HPA049426: " "unprognostic (2.36e-1)" "unprognostic (2.78e-1)" "unprognostic (4.08e-2)" "unprognostic (1.31e-1)" "unprognostic (1.58e-1)" "unprognostic (9.81e-2)" "unprognostic (2.57e-1)" "unprognostic (9.87e-3)" "unprognostic (5.79e-2)" "unprognostic (1.62e-1)" "potential prognostic favorable (4.28e-5)" "unprognostic (5.11e-1)" "unprognostic (2.32e-2)" "validated prognostic unfavorable (2.37e-4)" "validated prognostic unfavorable (2.58e-4)" "potential prognostic unfavorable (3.11e-4)" "unprognostic (4.41e-3)" "unprognostic (4.41e-1)" "unprognostic (9.92e-2)" "unprognostic (2.69e-1)" "unprognostic (1.19e-2)" "potential prognostic unfavorable (7.96e-5)" "unprognostic (4.04e-3)" "unprognostic (4.02e-2)" "unprognostic (5.04e-2)" "unprognostic (7.14e-3)" "unprognostic (7.08e-2)" "unprognostic (3.03e-1)" "unprognostic (2.35e-1)" "unprognostic (2.46e-3)" "unprognostic (1.04e-1)" SMPDL3A "ASM3A, ASML3a, FLJ20177, yR36GH4.1" ENSG00000172594 "Sphingomyelin phosphodiesterase acid like 3A" Q92484 6 122789049-122809720 "Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 179.4;Cytotrophoblasts: 168.3;Enterocytes: 379.3;Foveolar cells: 150.2;Kupffer cells: 293.1;Migrating cytotrophoblasts: 166.2;Syncytiotrophoblasts: 133.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 93.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 11 "basophil: 81.1" "Lineage enriched" "Detected in many" 11 "granulocytes: 81.1" "Cancer enhanced" "Detected in all" "prostate cancer: 39.9" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Fibroblasts, Spleen - Macrophages, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030148 Uncertain Approved Nucleoplasm,Nucleoli,Mitochondria "Secreted to blood" Enzyme No No 7000000 "Cluster 32: Basophils - Transcription" "Cluster 77: Intestine - Digestion" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" "Nucleoplasm, Nucleoli, Mitochondria" "HPA030148: " "unprognostic (1.46e-1)" "unprognostic (2.84e-2)" "unprognostic (1.23e-1)" "unprognostic (6.10e-2)" "unprognostic (2.30e-2)" "unprognostic (8.60e-2)" "unprognostic (2.35e-1)" "unprognostic (8.96e-3)" "unprognostic (5.41e-2)" "unprognostic (1.99e-2)" "potential prognostic favorable (1.18e-5)" "unprognostic (8.95e-3)" "unprognostic (1.54e-1)" "unprognostic (2.78e-1)" "unprognostic (1.35e-3)" "unprognostic (8.94e-2)" "unprognostic (2.88e-3)" "unprognostic (8.62e-2)" "unprognostic (4.11e-2)" "unprognostic (3.77e-1)" "unprognostic (2.38e-1)" "unprognostic (2.61e-1)" "unprognostic (2.85e-1)" "unprognostic (3.31e-1)" "unprognostic (2.94e-2)" "unprognostic (2.68e-1)" "unprognostic (3.59e-1)" "unprognostic (4.10e-2)" "unprognostic (2.36e-1)" "unprognostic (7.24e-3)" "unprognostic (5.15e-2)" SMPDL3B ASML3B ENSG00000130768 "Sphingomyelin phosphodiesterase acid like 3B" Q92485 1 27935000-27959157 "Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity, Lipid degradation, Lipid metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 22.6;pancreas: 46.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 39.6;Breast lactating cells: 103.3;Colonocytes: 58.1;Enteric stem cells: 40.3;Enteric transient amplifying cells: 43.5;Enterocytes: 45.4;Goblet cells: 31.6;Neutrophils: 87.3;Pancreatic acinar cells: 57.8;Plasma cells: 31.5;Transitional alveolar cells: 38.0" "Cell type enhanced" "Detected in many" "deep-layer corticothalamic and 6b: 7.8;deep-layer near-projecting: 6.3;eccentric medium spiny neuron: 5.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "eosinophil: 3.3;myeloid DC: 1.3;neutrophil: 1.7" "Group enriched" "Detected in many" 7 "dendritic cells: 1.3;granulocytes: 3.3" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Minor Salivary Gland - Minor salivary glandular cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Spleen - Plasma cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA030561 Approved "Golgi apparatus,Cytosol" "Secreted to blood" Immunity NA NA 300000 "Cluster 22: Eosinophils - Transcription" "Cluster 60: Stomach - Digestion" "Cluster 35: Non-specific - DNA binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 9 Cytosol "Golgi apparatus" "HPA030561: " "unprognostic (1.20e-1)" "unprognostic (2.04e-2)" "unprognostic (8.71e-2)" "unprognostic (7.75e-3)" "unprognostic (1.12e-1)" "potential prognostic favorable (1.21e-4)" "unprognostic (4.00e-2)" "unprognostic (2.72e-1)" "unprognostic (2.89e-2)" "unprognostic (1.91e-1)" "unprognostic (1.84e-1)" "unprognostic (1.79e-1)" "unprognostic (6.70e-2)" "unprognostic (2.82e-1)" "unprognostic (6.16e-2)" "unprognostic (1.72e-2)" "unprognostic (6.24e-2)" "unprognostic (6.87e-3)" "unprognostic (3.81e-1)" "unprognostic (1.17e-1)" "unprognostic (4.87e-1)" "unprognostic (4.04e-1)" "unprognostic (6.21e-2)" "unprognostic (3.55e-1)" "unprognostic (1.51e-1)" "unprognostic (2.72e-1)" "unprognostic (1.10e-1)" "unprognostic (3.01e-3)" "unprognostic (7.79e-2)" SMPX "Chisel, Csl, DFN6, DFNX4" ENSG00000091482 "Small muscle protein X-linked" Q9UHP9 X 21705978-21758116 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 38 "heart muscle: 709.4;skeletal muscle: 1108.9;tongue: 1025.1" "Group enriched" "Detected in some" 6 "Cardiomyocytes: 98.9;Myonuclei: 216.0;Thymic myoid cells: 254.2" "Group enriched" "Detected in some" 6 "cerebellar inhibitory: 6.5;mammillary body: 16.3;midbrain-derived inhibitory: 22.4;thalamic excitatory: 8.0" "Group enriched" "Detected in many" 5 "Head and Neck Squamous Cell Carcinoma (TCGA): 14.4;Stomach Adenocarcinoma (TCGA): 3.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "Rhabdoid: 13.8;Sarcoma: 17.9" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in many" "Region enhanced" "Detected in all" "cerebellum: 19.6" HPA077360 Approved "Plasma membrane" NA NA 24000 "Cluster 41: Striated muscle - Muscle contraction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 46: Skeletal myocytes - Muscle structure & formation" "Plasma membrane" "HPA077360: " "unprognostic (1.42e-1)" "unprognostic (5.74e-2)" "potential prognostic unfavorable (2.64e-5)" "unprognostic (1.13e-2)" "unprognostic (1.99e-1)" "potential prognostic unfavorable (8.54e-4)" "unprognostic (5.84e-2)" "unprognostic (6.97e-2)" "unprognostic (1.04e-2)" "unprognostic (3.37e-1)" "unprognostic (1.30e-1)" "unprognostic (1.07e-2)" "unprognostic (6.08e-3)" "unprognostic (5.88e-1)" SMR3A "PBI, PRL5, PROL5" ENSG00000109208 "Submaxillary gland androgen regulated protein 3A" Q99954 4 70360760-70367158 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 58 "salivary gland: 56.2" "Cell type enriched" "Detected in some" 25 "Lacrimal acinar cells: 2831.6" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Breast Invasive Carcinoma (TCGA): 1.7" "Region enhanced" "Detected in single" "midbrain: 1.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA044567 Enhanced "Secreted to digestive system" "No annotated function" NA NA "Cluster 82: Salivary gland - Secretion" "Cluster 46: Brainstem - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 3 "HPA044567: " SMR3B "P-B, PRL3, PROL3" ENSG00000171201 "Submaxillary gland androgen regulated protein 3B" P02814 4 70370093-70390244 "Essential proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 945 "salivary gland: 204297.4" "Cell type enriched" "Detected in some" 6 "Salivary acinar cells: 51728.9" "Cell type enriched" "Detected in single" 9 "thalamic excitatory: 1.0" "Cancer enriched" "Detected in some" 15 "Breast Invasive Carcinoma (TCGA): 152.7" "Region enhanced" "Detected in single" "midbrain: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "thyroid cancer: 44.3" "Testis - Late spermatids" "Secreted to digestive system" "No annotated function" NA NA 2200000 "Cluster 82: Salivary gland - Secretion" "Cluster 46: Brainstem - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 5 "unprognostic (3.08e-1)" "unprognostic (1.22e-1)" "unprognostic (2.76e-1)" "unprognostic (2.78e-1)" "unprognostic (1.90e-1)" SMS "MRSR, SPMSY, SpS, SRS" ENSG00000102172 "Spermine synthase" P52788 X 21940709-21994837 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Polyamine biosynthesis" Transferase "Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 795.7;Endometrial glandular cells: 544.2;Migrating cytotrophoblasts: 721.7;Oocytes: 1639.4;Syncytiotrophoblasts: 1123.6" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 496.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029849, HPA029852" Approved Approved "Nuclear bodies,Cytosol" No No 260000 "Cluster 7: Non-specific - Innate immune response" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 36: Non-specific - mRNA processing" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 5 "Nuclear bodies" Cytosol "HPA029849: , HPA029852: " "potential prognostic unfavorable (4.22e-4)" "potential prognostic unfavorable (5.47e-4)" "unprognostic (4.75e-2)" "unprognostic (5.97e-2)" "unprognostic (9.90e-2)" "unprognostic (5.83e-2)" "unprognostic (6.79e-2)" "unprognostic (4.26e-2)" "potential prognostic unfavorable (3.74e-4)" "unprognostic (5.97e-2)" "potential prognostic favorable (1.86e-5)" "unprognostic (4.18e-3)" "unprognostic (1.98e-2)" "potential prognostic unfavorable (5.06e-9)" "unprognostic (1.76e-3)" "validated prognostic unfavorable (5.49e-5)" "validated prognostic unfavorable (8.14e-4)" "unprognostic (1.33e-1)" "unprognostic (3.44e-2)" "unprognostic (3.06e-2)" "unprognostic (5.21e-2)" "potential prognostic unfavorable (8.47e-4)" "unprognostic (7.98e-3)" "unprognostic (2.91e-1)" "unprognostic (4.12e-2)" "unprognostic (2.12e-2)" "unprognostic (2.20e-1)" "unprognostic (2.83e-1)" "unprognostic (1.09e-1)" "unprognostic (1.63e-1)" "unprognostic (1.28e-1)" SMTN ENSG00000183963 Smoothelin P53814 22 31064105-31104757 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 441.9;intestine: 828.4;urinary bladder: 510.6" "Cell type enriched" "Detected in many" 5 "Smooth muscle cells: 1281.2" "Cell type enhanced" "Detected in many" "Bergmann glia: 246.5;pericyte: 88.0;vascular associated smooth muscle cell: 90.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Colon - Smooth muscle cells, Liver - Vascular endothelial cells, Lung - Smooth muscle cells, Minor Salivary Gland - Endothelial cells, Prostate - Smooth muscle cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001721, HPA051778, HPA058590" Enhanced Supported "Nucleoplasm,Actin filaments" No Yes 43000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 47: Endothelial cells - Vasculature" "Cluster 72: Neuronal - Signal transduction" "Cluster 62: Smooth muscle cells - Muscle contraction" 3 Nucleoplasm "Actin filaments" "CAB001721: , HPA051778: , HPA058590: " "unprognostic (2.10e-2)" "unprognostic (1.11e-1)" "unprognostic (3.43e-1)" "potential prognostic unfavorable (9.59e-4)" "unprognostic (4.00e-1)" "unprognostic (1.99e-1)" "unprognostic (5.46e-2)" "unprognostic (3.53e-1)" "unprognostic (2.42e-2)" "unprognostic (5.36e-2)" "validated prognostic favorable (5.73e-5)" "validated prognostic favorable (2.93e-5)" "unprognostic (2.39e-3)" "potential prognostic unfavorable (6.96e-4)" "unprognostic (5.27e-2)" "unprognostic (4.02e-2)" "unprognostic (1.32e-2)" "unprognostic (2.85e-2)" "unprognostic (8.76e-2)" "unprognostic (2.17e-1)" "unprognostic (1.06e-1)" "unprognostic (1.36e-1)" "unprognostic (3.35e-1)" "unprognostic (5.97e-2)" "unprognostic (1.87e-1)" "unprognostic (7.60e-2)" "unprognostic (6.90e-3)" "unprognostic (4.53e-2)" "unprognostic (2.03e-1)" "unprognostic (1.75e-2)" "unprognostic (6.82e-2)" SMTNL1 CHASM ENSG00000214872 "Smoothelin like 1" A8MU46 11 57537595-57550272 "Predicted intracellular proteins" "Calmodulin-binding, Muscle protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 51 "skeletal muscle: 651.9;tongue: 174.6" "Cell type enriched" "Detected in some" 9 "Myonuclei: 109.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney Chromophobe (TCGA): 3.8" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in some" "Kidney - T-cells, Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 44: Non-specific - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" "unprognostic (2.95e-1)" "unprognostic (1.21e-1)" "unprognostic (2.85e-1)" "unprognostic (4.24e-2)" "unprognostic (1.41e-1)" "unprognostic (7.88e-2)" "unprognostic (1.32e-1)" "unprognostic (1.83e-2)" "unprognostic (1.12e-3)" SMTNL2 FLJ42461 ENSG00000188176 "Smoothelin like 2" Q2TAL5 17 4583999-4608319 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "skeletal muscle: 477.4;tongue: 127.1" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 37.3;Epicardial cells: 40.9;Epididymal efferent duct absorptive cells: 23.3;Loop of henle epithelial cells: 51.6;Mesothelial cells: 31.8;Myonuclei: 163.5;Pericytes: 22.8;Proximal tubule cells: 60.1;Renal connecting tubule cells: 17.9;Thymic myoid cells: 29.9" "Cell type enhanced" "Detected in some" "endothelial cell: 5.0;fibroblast: 3.6" "Group enriched" "Detected in many" 5 "Kidney Renal Clear Cell Carcinoma (TCGA): 14.2;Kidney Renal Papillary Cell Carcinoma (TCGA): 38.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 9.2" "Adipose visceral - Mesothelial cells, Pituitary gland - Corticotropes, Prostate - Fibroblasts, Skin - Hair cortex cells, Skin - Inner root sheath cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA025706 Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 29: Forebrain - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" "Nucleoplasm, Nuclear speckles" "HPA025706: " "unprognostic (1.87e-1)" "unprognostic (2.39e-2)" "potential prognostic favorable (6.42e-4)" "unprognostic (2.66e-1)" "unprognostic (4.81e-1)" "unprognostic (4.75e-2)" "potential prognostic favorable (5.31e-4)" "validated prognostic favorable (1.69e-6)" "validated prognostic favorable (1.41e-6)" "potential prognostic favorable (5.88e-5)" "unprognostic (2.30e-2)" "unprognostic (2.34e-1)" "unprognostic (1.90e-1)" "unprognostic (9.39e-2)" "unprognostic (5.80e-2)" "unprognostic (1.02e-1)" "unprognostic (4.86e-2)" "unprognostic (4.90e-2)" "unprognostic (5.37e-3)" SMU1 "BWD, FLJ10805, fSAP57, SMU-1" ENSG00000122692 "SMU1 DNA replication regulator and spliceosomal factor" Q2TAY7 9 33041765-33076674 "Essential proteins, Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019708 Supported Approved Vesicles NA NA 370000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 41 Vesicles "HPA019708: " "unprognostic (1.28e-1)" "unprognostic (2.11e-1)" "unprognostic (3.54e-2)" "unprognostic (3.11e-2)" "unprognostic (5.76e-2)" "unprognostic (3.91e-2)" "unprognostic (6.46e-2)" "unprognostic (2.30e-3)" "unprognostic (7.17e-2)" "unprognostic (1.94e-1)" "potential prognostic favorable (3.75e-7)" "unprognostic (1.36e-3)" "unprognostic (1.96e-1)" "potential prognostic unfavorable (3.50e-4)" "unprognostic (2.57e-2)" "unprognostic (4.58e-2)" "unprognostic (6.88e-3)" "unprognostic (2.36e-1)" "unprognostic (3.09e-2)" "unprognostic (4.71e-2)" "unprognostic (2.88e-1)" "unprognostic (1.55e-2)" "unprognostic (1.83e-1)" "unprognostic (1.38e-1)" "unprognostic (2.45e-2)" "unprognostic (3.09e-1)" "unprognostic (1.56e-1)" "unprognostic (1.91e-1)" "unprognostic (3.35e-1)" "unprognostic (1.96e-1)" "unprognostic (9.26e-2)" SMUG1 "FDG, HMUDG, UNG3" ENSG00000123415 "Single-strand-selective monofunctional uracil-DNA glycosylase 1" Q53HV7 12 54121277-54189008 "Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 106.7;Esophageal apical cells: 166.9;Esophageal suprabasal cells: 118.2;Extravillous trophoblasts: 123.4;Migrating cytotrophoblasts: 110.3;Syncytiotrophoblasts: 115.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026804, HPA065892" Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 70: Non-specific - Protein processing" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 38: Non-specific - Transcription" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 9 Nucleoplasm "Nucleoli fibrillar center, Cytosol" "HPA026804: , HPA065892: " "unprognostic (4.92e-3)" "unprognostic (2.90e-1)" "unprognostic (6.50e-2)" "unprognostic (7.93e-2)" "unprognostic (1.82e-2)" "unprognostic (2.92e-2)" "unprognostic (1.47e-3)" "unprognostic (5.48e-3)" "unprognostic (7.13e-2)" "unprognostic (7.87e-3)" "potential prognostic unfavorable (8.65e-5)" "unprognostic (3.07e-2)" "unprognostic (8.62e-2)" "validated prognostic unfavorable (7.69e-4)" "validated prognostic unfavorable (3.75e-6)" "unprognostic (1.17e-3)" "unprognostic (3.86e-2)" "unprognostic (7.87e-2)" "unprognostic (1.22e-1)" "unprognostic (4.79e-3)" "unprognostic (8.16e-2)" "potential prognostic unfavorable (9.13e-4)" "unprognostic (8.93e-2)" "unprognostic (3.36e-2)" "unprognostic (1.14e-1)" "unprognostic (5.74e-2)" "unprognostic (5.15e-2)" "unprognostic (3.90e-1)" "unprognostic (3.38e-1)" "unprognostic (3.52e-1)" "unprognostic (2.95e-2)" SMURF1 KIAA1625 ENSG00000198742 "SMAD specific E3 ubiquitin protein ligase 1" Q9HCE7 7 99027440-99144108 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Differentiation, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Renal collecting duct intercalated cells: 471.8" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Ovary Serous Cystadenocarcinoma (TCGA): 4.6;Stomach Adenocarcinoma (TCGA): 9.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019671, HPA055245" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 11: White matter - Signal transduction" "Cluster 39: Non-specific - Transcription" "Cluster 102: Non-specific - Mixed function" 93 Vesicles Nucleoplasm "HPA019671: , HPA055245: " "unprognostic (1.96e-1)" "unprognostic (8.56e-2)" "unprognostic (1.22e-1)" "unprognostic (2.55e-1)" "unprognostic (1.08e-1)" "unprognostic (2.42e-3)" "unprognostic (6.55e-3)" "unprognostic (1.67e-1)" "potential prognostic unfavorable (1.75e-4)" "unprognostic (3.68e-2)" "unprognostic (1.89e-1)" SMURF2 ENSG00000108854 "SMAD specific E3 ubiquitin protein ligase 2" Q9HAU4 17 64542282-64662307 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Enterocytes: 509.3;Thymocytes: 445.5" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 431.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 180.1" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071508 Enhanced Supported "Nuclear speckles" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 7: Non-specific - Ribosome" "Cluster 72: Neuronal - Signal transduction" "Cluster 51: Secretory epithelial cells - Mixed function" 84 "Nuclear speckles" "HPA071508: " "unprognostic (1.80e-2)" "unprognostic (2.23e-1)" "unprognostic (8.06e-2)" "unprognostic (4.11e-2)" "unprognostic (5.58e-2)" "potential prognostic unfavorable (8.57e-5)" "unprognostic (3.62e-1)" "unprognostic (6.93e-2)" "unprognostic (2.55e-1)" "unprognostic (8.14e-3)" "validated prognostic favorable (1.66e-6)" "validated prognostic favorable (2.66e-4)" "unprognostic (1.24e-1)" "unprognostic (2.33e-2)" "unprognostic (1.45e-1)" "unprognostic (3.10e-2)" "unprognostic (1.43e-2)" "unprognostic (3.19e-1)" "unprognostic (4.17e-2)" "unprognostic (1.88e-2)" "unprognostic (3.18e-3)" "potential prognostic unfavorable (4.37e-4)" "unprognostic (1.50e-1)" "unprognostic (9.50e-3)" "unprognostic (2.04e-2)" "unprognostic (4.40e-2)" "unprognostic (2.39e-1)" "unprognostic (1.58e-1)" "unprognostic (3.07e-2)" "unprognostic (8.44e-2)" SMYD1 "BOP, KMT3D, ZMYND22" ENSG00000115593 "SET and MYND domain containing 1" Q8NB12 2 88067825-88113384 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Methyltransferase, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "heart muscle: 152.8;skeletal muscle: 462.4;tongue: 281.3" "Group enriched" "Detected in some" 9 "Cardiomyocytes: 350.5;Myonuclei: 392.8;Thymic myoid cells: 111.5" "Cell type enriched" "Detected in single" 11 "deep-layer intratelencephalic: 10.2" "Cancer enhanced" "Detected in some" "Head and Neck Squamous Cell Carcinoma (TCGA): 1.5;Stomach Adenocarcinoma (TCGA): 2.7" "Region enriched" "Detected in some" 5 "cerebral cortex: 8.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 14 "Sarcoma: 2.2" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA062282 Enhanced NA NA "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 53: Neurons - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 55: Myocytes - Oxidative muscle function" 39 "HPA062282: " "unprognostic (1.26e-1)" "unprognostic (1.17e-2)" "unprognostic (3.77e-3)" SMYD2 "HSKM-B, KMT3C, ZMYND14" ENSG00000143499 "SET and MYND domain containing 2" Q9NRG4 1 214281102-214337131 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "heart muscle: 183.6;skeletal muscle: 86.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 192.8;Cytotrophoblasts: 271.3;Early spermatids: 206.9;Migrating cytotrophoblasts: 207.4;Parietal cells: 226.3;Respiratory ciliated cells: 188.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Stomach - Parietal cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029023 Uncertain Approved Mitochondria,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 70: DU4475 - Unknown function" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 20 Cytosol Mitochondria "HPA029023: " "unprognostic (5.36e-2)" "unprognostic (2.89e-1)" "unprognostic (4.93e-2)" "potential prognostic unfavorable (9.97e-6)" "unprognostic (7.67e-2)" "unprognostic (1.25e-2)" "unprognostic (1.27e-1)" "unprognostic (1.03e-1)" "unprognostic (1.43e-2)" "unprognostic (2.41e-1)" "potential prognostic favorable (5.47e-9)" "unprognostic (1.47e-1)" "unprognostic (3.23e-1)" "unprognostic (9.55e-3)" "unprognostic (3.16e-2)" "unprognostic (2.29e-3)" "unprognostic (3.30e-1)" "unprognostic (2.89e-1)" "unprognostic (1.97e-2)" "unprognostic (3.08e-1)" "unprognostic (7.70e-3)" "unprognostic (1.03e-1)" "unprognostic (1.21e-2)" "unprognostic (1.35e-1)" "unprognostic (1.87e-2)" "unprognostic (1.69e-2)" "unprognostic (5.27e-2)" "unprognostic (4.13e-1)" "unprognostic (5.21e-2)" "unprognostic (4.76e-2)" "unprognostic (1.30e-1)" SMYD3 "KMT3E, ZMYND1, ZNFN3A1" ENSG00000185420 "SET and MYND domain containing 3" Q9H7B4 1 245749342-246507312 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Chromatin regulator, Methyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012229, HPA045821, HPA054352" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 22: Epididymis - Mixed function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 7: Non-specific - Transcription" 14 Nucleoplasm Cytosol "CAB012229: , HPA045821: , HPA054352: " "unprognostic (6.25e-2)" "unprognostic (2.50e-2)" "unprognostic (2.38e-2)" "unprognostic (3.32e-2)" "unprognostic (5.96e-2)" "potential prognostic favorable (5.88e-4)" "unprognostic (1.81e-1)" "unprognostic (1.77e-3)" "unprognostic (5.54e-2)" "unprognostic (4.71e-2)" "potential prognostic favorable (2.28e-5)" "unprognostic (3.56e-1)" "unprognostic (3.28e-2)" "unprognostic (1.35e-3)" "potential prognostic unfavorable (2.18e-5)" "unprognostic (1.10e-1)" "unprognostic (9.69e-2)" "unprognostic (1.92e-1)" "unprognostic (1.77e-2)" "unprognostic (6.98e-3)" "unprognostic (1.28e-3)" "unprognostic (3.59e-2)" "unprognostic (9.22e-2)" "unprognostic (4.05e-1)" "unprognostic (3.26e-3)" "unprognostic (5.21e-2)" "unprognostic (1.64e-1)" "unprognostic (2.01e-2)" "unprognostic (8.47e-3)" "unprognostic (1.12e-2)" "unprognostic (1.73e-2)" SMYD4 "KIAA1936, ZMYND21" ENSG00000186532 "SET and MYND domain containing 4" Q8IYR2 17 1779485-1830634 "Predicted intracellular proteins, Predicted membrane proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 79.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Pituitary gland - Corticotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030059 Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 49: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 94: Gonadal somatic cells - Mixed function" 1 "Golgi apparatus, Vesicles" "Nucleoplasm, Cytosol" "HPA030059: " "unprognostic (1.99e-1)" "unprognostic (1.54e-1)" "unprognostic (9.55e-2)" "unprognostic (3.11e-2)" "unprognostic (7.37e-2)" "unprognostic (1.65e-1)" "unprognostic (4.40e-2)" "unprognostic (2.58e-1)" "unprognostic (2.55e-2)" "unprognostic (2.93e-2)" "unprognostic (1.40e-2)" "unprognostic (4.36e-3)" "unprognostic (2.58e-3)" "unprognostic (2.59e-2)" "unprognostic (2.28e-1)" "unprognostic (1.22e-1)" "unprognostic (6.48e-2)" "unprognostic (2.10e-1)" "unprognostic (1.16e-1)" "unprognostic (1.90e-1)" "unprognostic (1.57e-1)" "unprognostic (3.50e-3)" "unprognostic (8.61e-3)" "unprognostic (8.39e-2)" "unprognostic (1.62e-2)" "unprognostic (1.28e-1)" "unprognostic (1.49e-2)" "unprognostic (1.09e-1)" "unprognostic (3.88e-1)" "unprognostic (9.67e-2)" "unprognostic (3.56e-1)" SMYD5 "NN8-4AG, RAI15, RRG1, ZMYND23" ENSG00000135632 "SMYD family member 5" Q6GMV2 2 73214222-73227221 "Enzymes, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015514, HPA049002" Uncertain Approved Nucleoplasm NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 24: Neurons - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 7: Non-specific - Transcription" 2 Nucleoplasm "HPA015514: , HPA049002: " "unprognostic (9.24e-2)" "unprognostic (9.47e-2)" "unprognostic (1.48e-1)" "unprognostic (7.43e-2)" "unprognostic (7.87e-2)" "unprognostic (2.15e-1)" "unprognostic (2.72e-1)" "unprognostic (3.17e-2)" "unprognostic (7.33e-2)" "unprognostic (7.78e-3)" "unprognostic (2.88e-2)" "unprognostic (4.56e-1)" "unprognostic (6.09e-3)" "validated prognostic unfavorable (8.35e-9)" "validated prognostic unfavorable (9.30e-6)" "unprognostic (1.22e-1)" "unprognostic (2.73e-3)" "unprognostic (2.36e-1)" "unprognostic (1.04e-2)" "unprognostic (1.76e-2)" "unprognostic (1.79e-1)" "unprognostic (1.86e-2)" "unprognostic (9.39e-3)" "unprognostic (1.42e-2)" "unprognostic (4.55e-2)" "unprognostic (1.84e-1)" "unprognostic (1.89e-1)" "unprognostic (1.45e-1)" "unprognostic (5.29e-2)" "unprognostic (2.34e-1)" "unprognostic (1.66e-2)" SNAI1 "SLUGH2, SNA, SNAH, SNAIL, SNAIL1" ENSG00000124216 "Snail family transcriptional repressor 1" O95863 20 49982980-49988886 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 28.6" "Cell type enhanced" "Detected in many" "Breast lactating cells: 61.1;Breast myoepithelial cells: 32.7;Breast secretory cells: 38.4;cDC: 35.8;Extravillous trophoblasts: 115.7;Hepatic stellate cells: 45.2;Migrating cytotrophoblasts: 34.1;monocytes: 30.9;pDCs: 54.7;Tuft cells: 46.1;Vascular endothelial cells: 48.5" "Cell type enhanced" "Detected in some" "fibroblast: 3.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.2" "Lineage enriched" "Detected in single" 6 "dendritic cells: 1.2" "Low cancer specificity" "Detected in many" "Breast - Adipocytes (Breast)" "Not detected" "Not detected" "Region enriched" "Detected in some" 8 "spinal cord: 9.3" "CAB005883, HPA056831, HPA069985, CAB078687, CAB080398" Supported Supported Nucleoplasm NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 55: Non-specific - Transcription" "Cluster 69: Skin cancer - ECM organization" "Cluster 20: Non-specific - Transcription regulation" 95 Nucleoplasm "CAB005883: , CAB078687: , CAB080398: , HPA056831: , HPA069985: " "unprognostic (1.51e-1)" "unprognostic (5.06e-3)" "unprognostic (1.25e-2)" "unprognostic (1.73e-3)" "unprognostic (2.03e-3)" "unprognostic (1.97e-1)" "unprognostic (1.84e-3)" "potential prognostic unfavorable (7.48e-4)" "unprognostic (2.90e-2)" "unprognostic (5.42e-1)" "unprognostic (3.18e-2)" "unprognostic (1.70e-2)" "potential prognostic unfavorable (9.30e-4)" "unprognostic (3.46e-1)" "unprognostic (2.32e-2)" "potential prognostic unfavorable (9.71e-4)" "unprognostic (6.30e-2)" "potential prognostic unfavorable (2.60e-4)" "unprognostic (1.82e-1)" "unprognostic (8.62e-3)" "unprognostic (2.97e-2)" "unprognostic (1.05e-1)" "unprognostic (1.17e-1)" "unprognostic (2.60e-1)" "unprognostic (7.06e-2)" "unprognostic (1.12e-2)" "potential prognostic unfavorable (2.58e-5)" "unprognostic (6.13e-3)" "unprognostic (2.25e-1)" "potential prognostic unfavorable (2.06e-6)" "unprognostic (9.53e-2)" SNAI2 "SLUG, SLUGH, SLUGH1, SNAIL2" ENSG00000019549 "Snail family transcriptional repressor 2" O43623 8 48917598-48921740 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Deafness, Waardenburg syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 121.1;Breast myoepithelial cells: 49.9;Decidual stromal cells: 123.6;Endometrial stromal cells: 100.9;Epididymal basal cells: 47.6;Esophageal basal cells: 40.0;Fibroblasts: 74.2;Leydig cells: 47.8;Melanocytes: 141.8;Myosatellite cells: 43.9;Ovarian stromal cells: 47.9;Pericytes: 64.4;Peritubular myoid cells: 57.1;Suprabasal keratinocytes: 87.0" "Cell type enhanced" "Detected in some" "pericyte: 10.7;vascular associated smooth muscle cell: 5.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Kidney - Fibroblasts, Spleen - Fibroblasts_2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA000971, CAB011671, HPA065884" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 75: Ovary - Mixed function" "Cluster 35: Non-specific - DNA binding" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 17 Nucleoplasm Cytosol "CAB011671: , HPA000971: , HPA065884: " "unprognostic (5.59e-2)" "unprognostic (1.56e-1)" "unprognostic (1.53e-2)" "unprognostic (2.47e-1)" "unprognostic (1.30e-1)" "unprognostic (8.94e-2)" "unprognostic (2.07e-2)" "unprognostic (1.36e-2)" "unprognostic (9.42e-3)" "unprognostic (2.07e-2)" "unprognostic (1.75e-1)" "unprognostic (1.62e-1)" "potential prognostic unfavorable (1.88e-5)" "unprognostic (2.15e-1)" "unprognostic (5.46e-2)" "unprognostic (1.47e-3)" "unprognostic (1.01e-2)" "unprognostic (5.25e-2)" "unprognostic (3.67e-1)" "unprognostic (3.83e-3)" "unprognostic (2.32e-3)" "unprognostic (3.16e-3)" "unprognostic (1.96e-3)" "unprognostic (2.26e-1)" "unprognostic (5.86e-2)" "unprognostic (8.70e-2)" "unprognostic (1.14e-1)" "unprognostic (1.10e-3)" "unprognostic (5.79e-2)" "unprognostic (7.74e-2)" "unprognostic (1.46e-2)" SNAI3 "SMUC, Zfp293, ZNF293" ENSG00000185669 "Snail family transcriptional repressor 3" Q3KNW1 16 88677688-88686507 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 4 "skeletal muscle: 29.3" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 23.4;Early primary spermatocytes: 47.4;Myonuclei: 45.3;Neutrophils: 25.0;Plasma cells: 21.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Adipose visceral - T-cells, Breast - Plasma cells, Heart muscle - Cardiomyocytes, Prostate - T-cells, Testis - Spermatogonia, Thyroid gland - T-cells" "Region enhanced" "Detected in single" "basal ganglia: 1.5" "Not detected" "Not detected" HPA071127 Approved Nucleoplasm NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" Nucleoplasm "HPA071127: " "unprognostic (1.75e-2)" "unprognostic (1.36e-2)" "potential prognostic favorable (9.90e-6)" "unprognostic (4.38e-2)" "unprognostic (1.35e-1)" "unprognostic (2.32e-1)" "unprognostic (6.71e-3)" "unprognostic (2.89e-1)" "unprognostic (1.89e-1)" "unprognostic (3.13e-1)" "unprognostic (1.02e-1)" "potential prognostic favorable (6.68e-5)" "unprognostic (1.55e-1)" "unprognostic (8.93e-2)" "unprognostic (5.22e-3)" "unprognostic (1.24e-1)" "unprognostic (3.77e-2)" "unprognostic (1.69e-1)" "unprognostic (6.20e-2)" "unprognostic (1.47e-2)" "unprognostic (4.53e-2)" "unprognostic (6.07e-2)" SNAP23 "HsT17016, SNAP23A, SNAP23B" ENSG00000092531 "Synaptosome associated protein 23" O00161 15 42491233-42545356 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 400.6;Megakaryocytes: 500.7;Platelets: 1140.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 681.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Colon - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001214, CAB037083, CAB037317" Approved Supported "Plasma membrane,Primary cilium" NA NA 2000000 "Cluster 35: Neutrophils - Protein binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 11: White matter - Signal transduction" "Cluster 58: Non-specific - Nuclear processes" "Cluster 47: Platelets - Hemostasis" 57 "Plasma membrane" "Primary cilium" "CAB037083: , CAB037317: , HPA001214: " "unprognostic (2.23e-2)" "unprognostic (9.35e-2)" "unprognostic (2.00e-1)" "unprognostic (2.91e-2)" "unprognostic (6.42e-2)" "unprognostic (3.03e-1)" "unprognostic (6.93e-2)" "unprognostic (3.12e-1)" "unprognostic (2.12e-1)" "unprognostic (1.48e-3)" "unprognostic (1.06e-3)" "unprognostic (3.85e-2)" "unprognostic (2.58e-1)" "unprognostic (1.58e-3)" "unprognostic (2.42e-2)" "unprognostic (9.14e-2)" "unprognostic (2.28e-2)" "unprognostic (8.19e-2)" "unprognostic (3.43e-3)" "unprognostic (4.06e-2)" "unprognostic (3.11e-3)" "unprognostic (1.82e-2)" "unprognostic (1.36e-2)" "unprognostic (1.37e-1)" "unprognostic (6.17e-2)" "unprognostic (3.55e-2)" "unprognostic (2.86e-2)" "unprognostic (4.95e-2)" "unprognostic (1.37e-1)" "unprognostic (1.04e-1)" "unprognostic (1.46e-1)" SNAP25 "bA416N4.2, dJ1068F16.2, RIC-4, RIC4, SEC9, SNAP, SNAP-25" ENSG00000132639 "Synaptosome associated protein 25" P60880 20 10172395-10308258 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Transporters" "Congenital myasthenic syndrome, Disease variant, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 2270.3" "Cell type enhanced" "Detected in many" "Bergmann glia: 298.6;Brain excitatory neurons: 1191.9;Brain inhibitory neurons: 675.5;Cone photoreceptor cells: 308.4;Corticotrophs: 283.8;Gonadotrophs: 583.8;Lactotrophs: 743.4;Neuroendocrine cells: 264.5;Other brain neurons: 419.7;Pancreatic islet cells: 372.8;Retinal amacrine cells: 482.2;Retinal bipolar cells: 836.8;Retinal ganglion cells: 521.5;Rod photoreceptor cells: 432.4;Somatotrophs: 579.8" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 6 "Glioblastoma Multiforme (TCGA): 76.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 52.2" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Pituitary gland - Lactotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000360, HPA001830, HPA071013" Enhanced Supported Approved "Vesicles,Plasma membrane" NA NA 20000 "Cluster 27: Cerebellum - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 22 "Plasma membrane" Vesicles "CAB000360: , HPA001830: , HPA071013: " "unprognostic (1.42e-1)" "unprognostic (3.91e-2)" "unprognostic (1.69e-1)" "unprognostic (6.81e-3)" "unprognostic (5.79e-2)" "unprognostic (2.24e-2)" "unprognostic (1.60e-2)" "unprognostic (2.53e-1)" "potential prognostic favorable (5.15e-4)" "unprognostic (1.37e-1)" "unprognostic (4.42e-1)" "unprognostic (2.51e-1)" "unprognostic (2.73e-1)" "unprognostic (2.08e-2)" "unprognostic (2.34e-2)" "potential prognostic unfavorable (3.07e-4)" "unprognostic (2.21e-2)" "unprognostic (7.48e-3)" "unprognostic (8.10e-2)" "unprognostic (1.90e-1)" "unprognostic (1.32e-1)" "unprognostic (6.10e-3)" "unprognostic (2.32e-1)" "unprognostic (3.07e-2)" "unprognostic (1.27e-2)" SNAP29 "CEDNIK, SNAP-29" ENSG00000099940 "Synaptosome associated protein 29" O95721 22 20859007-20891214 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Autophagy, Cilium biogenesis/degradation, Protein transport, Transport" "Ichthyosis, Neuropathy, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 488.0;Esophageal apical cells: 321.1;Extravillous trophoblasts: 212.7;Late primary spermatocytes: 489.1;Late spermatids: 193.4;Platelets: 211.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031823, CAB037092, HPA056492" Supported Supported Centrosome,Cytosol NA NA 26000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 39: Testis - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 66: Non-specific - Mitochondria" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 167 Cytosol Centrosome "CAB037092: , HPA031823: , HPA056492: " "unprognostic (1.83e-1)" "unprognostic (1.51e-1)" "unprognostic (3.71e-1)" "unprognostic (2.95e-2)" "unprognostic (2.33e-2)" "unprognostic (2.49e-1)" "unprognostic (2.69e-1)" "unprognostic (9.02e-2)" "potential prognostic unfavorable (6.47e-4)" "potential prognostic unfavorable (1.78e-5)" "potential prognostic favorable (2.58e-6)" "unprognostic (1.53e-2)" "unprognostic (1.62e-1)" "unprognostic (5.11e-3)" "unprognostic (1.70e-3)" "unprognostic (8.80e-2)" "unprognostic (3.85e-2)" "unprognostic (4.14e-2)" "unprognostic (2.94e-2)" "unprognostic (2.52e-2)" "unprognostic (5.25e-3)" "unprognostic (2.60e-3)" "unprognostic (5.02e-2)" "unprognostic (7.75e-3)" "unprognostic (1.27e-3)" "unprognostic (1.92e-1)" "unprognostic (1.60e-1)" "unprognostic (1.32e-1)" "unprognostic (6.74e-2)" "unprognostic (1.22e-1)" "unprognostic (3.67e-1)" SNAP47 "C1orf142, SNAP-47, SVAP1" ENSG00000143740 "Synaptosome associated protein 47" Q5SQN1 1 227728200-227781826 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 81.6;Late spermatids: 141.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Liver - Hepatocytes, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028167 Supported Approved Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 75: Ovary - Mixed function" "Cluster 33: Neurons - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 94: Gonadal somatic cells - Mixed function" 27 Cytosol "HPA028167: " "unprognostic (1.24e-1)" "unprognostic (3.87e-3)" "unprognostic (3.99e-2)" "unprognostic (2.83e-1)" "unprognostic (1.08e-1)" "unprognostic (1.18e-1)" "unprognostic (6.30e-2)" "unprognostic (5.29e-3)" "unprognostic (1.47e-1)" "unprognostic (1.60e-2)" "potential prognostic favorable (3.34e-4)" "unprognostic (3.05e-1)" "unprognostic (4.61e-2)" "unprognostic (2.69e-1)" "unprognostic (8.29e-2)" "unprognostic (1.75e-2)" "unprognostic (2.85e-3)" "unprognostic (1.13e-1)" "unprognostic (1.60e-2)" "unprognostic (3.28e-1)" "unprognostic (4.00e-2)" "unprognostic (3.03e-1)" "unprognostic (4.41e-1)" "unprognostic (1.90e-1)" "unprognostic (7.32e-2)" "unprognostic (5.90e-2)" "unprognostic (5.92e-2)" "unprognostic (3.87e-2)" "unprognostic (1.79e-2)" "unprognostic (6.19e-2)" "unprognostic (2.85e-2)" SNAP91 "AP180, CALM, KIAA0656" ENSG00000065609 "Synaptosome associated protein 91" O60641 6 83552880-83709691 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 105.4;retina: 85.1" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 234.0;Brain excitatory neurons: 432.0;Brain inhibitory neurons: 342.9;Choroid plexus epithelial cells: 300.8;Cone photoreceptor cells: 492.7;Corticotrophs: 359.9;Gonadotrophs: 325.3;Lactotrophs: 378.1;Oligodendrocyte progenitor cells: 290.1;Other brain neurons: 355.7;Retinal amacrine cells: 328.8;Retinal bipolar cells: 336.8;Retinal ganglion cells: 339.9;Rod photoreceptor cells: 475.9;Somatotrophs: 322.9;Thyrotrophs: 547.7" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Glioblastoma Multiforme (TCGA): 7.8;Pancreatic Adenocarcinoma (TCGA): 2.5;Prostate Adenocarcinoma (TCGA): 6.3;Testicular Germ Cell Tumor (TCGA): 2.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 24 "plasmacytoid DC: 2.8" "Lineage enriched" "Detected in single" 24 "dendritic cells: 2.8" "Cancer enriched" "Detected in some" 11 "Neuroblastoma: 38.1" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009745, HPA029632, HPA029633" Enhanced Approved "Centriolar satellite,Cytosol" NA NA 8500 "Cluster 27: Cerebellum - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 3 Cytosol "Centriolar satellite" "CAB009745: , HPA029632: , HPA029633: " "unprognostic (1.23e-1)" "unprognostic (2.85e-1)" "potential prognostic favorable (4.88e-6)" "potential prognostic favorable (9.66e-4)" "unprognostic (1.71e-1)" "unprognostic (2.29e-1)" "unprognostic (4.64e-2)" SNAPC1 "PTFgamma, SNAP43" ENSG00000023608 "Small nuclear RNA activating complex polypeptide 1" Q16533 14 61762420-61796428 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 139.6;Late primary spermatocytes: 150.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067076, HPA072276" Enhanced Nucleoplasm,Nucleoli NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 72: Neuronal - Signal transduction" "Cluster 51: Secretory epithelial cells - Mixed function" 23 Nucleoli Nucleoplasm "HPA067076: , HPA072276: " "unprognostic (2.02e-1)" "unprognostic (1.22e-1)" "unprognostic (6.04e-2)" "unprognostic (1.11e-2)" "unprognostic (2.30e-2)" "unprognostic (1.98e-1)" "unprognostic (3.01e-1)" "unprognostic (1.53e-2)" "unprognostic (2.30e-2)" "unprognostic (2.40e-2)" "unprognostic (2.16e-3)" "unprognostic (1.72e-1)" "unprognostic (1.49e-1)" "unprognostic (3.08e-3)" "unprognostic (9.33e-2)" "unprognostic (1.82e-1)" "potential prognostic unfavorable (2.49e-5)" "unprognostic (6.99e-3)" "unprognostic (3.88e-1)" "unprognostic (2.29e-1)" "unprognostic (1.58e-2)" "unprognostic (1.10e-1)" "unprognostic (2.33e-3)" "unprognostic (1.86e-1)" "unprognostic (2.05e-1)" "unprognostic (1.55e-1)" "unprognostic (7.81e-2)" "unprognostic (6.30e-2)" "unprognostic (1.43e-1)" "unprognostic (2.02e-1)" "unprognostic (1.25e-1)" SNAPC2 "PTFdelta, SNAP45" ENSG00000104976 "Small nuclear RNA activating complex polypeptide 2" Q13487 19 7920338-7923250 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 87.3;Oocytes: 64.5;Smooth muscle cells: 47.1;Undifferentiated spermatogonia: 47.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049843, HPA077597" Supported Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 62: Smooth muscle cells - Muscle contraction" 5 "Nucleoplasm, Nuclear bodies" Cytosol "HPA049843: , HPA077597: " "unprognostic (3.23e-3)" "unprognostic (7.26e-3)" "unprognostic (5.73e-2)" "unprognostic (2.09e-2)" "unprognostic (2.43e-1)" "unprognostic (1.25e-1)" "unprognostic (5.48e-2)" "unprognostic (1.95e-1)" "unprognostic (9.85e-2)" "unprognostic (3.32e-2)" "unprognostic (1.18e-2)" "unprognostic (6.39e-3)" "unprognostic (2.27e-2)" "potential prognostic unfavorable (1.97e-5)" "unprognostic (3.00e-2)" "unprognostic (1.12e-1)" "unprognostic (6.61e-3)" "unprognostic (1.65e-1)" "unprognostic (2.89e-2)" "unprognostic (9.62e-2)" "unprognostic (2.52e-1)" "unprognostic (8.89e-2)" "unprognostic (2.21e-1)" "unprognostic (4.84e-1)" "unprognostic (4.52e-2)" "unprognostic (1.68e-1)" "unprognostic (1.05e-1)" "unprognostic (2.59e-1)" "unprognostic (5.39e-2)" "unprognostic (1.63e-1)" "unprognostic (1.01e-2)" SNAPC3 "MGC132011, MGC33124, PTFbeta, SNAP50" ENSG00000164975 "Small nuclear RNA activating complex polypeptide 3" Q92966 9 15422734-15465953 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 402.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053145, HPA066031" Supported "Nucleoplasm,Nucleoli,Nuclear bodies" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 37: Neurons - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 13 "Nucleoplasm, Nuclear bodies" Nucleoli "HPA053145: , HPA066031: " "unprognostic (5.62e-2)" "unprognostic (1.88e-2)" "unprognostic (2.72e-1)" "unprognostic (4.41e-3)" "unprognostic (1.06e-3)" "unprognostic (6.98e-2)" "unprognostic (1.73e-2)" "unprognostic (2.61e-2)" "unprognostic (1.61e-1)" "unprognostic (5.48e-3)" "unprognostic (8.56e-3)" "unprognostic (1.31e-2)" "unprognostic (1.21e-1)" "unprognostic (5.90e-3)" "unprognostic (2.03e-1)" "unprognostic (2.08e-1)" "unprognostic (1.58e-1)" "unprognostic (1.13e-1)" "unprognostic (1.03e-1)" "unprognostic (6.98e-2)" "unprognostic (1.11e-1)" "unprognostic (3.55e-2)" "unprognostic (5.14e-2)" "potential prognostic unfavorable (7.50e-4)" "unprognostic (1.20e-1)" "unprognostic (6.21e-2)" "unprognostic (4.93e-3)" "unprognostic (8.83e-3)" "unprognostic (2.90e-1)" "unprognostic (1.17e-1)" "unprognostic (2.38e-3)" SNAPC4 "FLJ13451, PTFalpha, SNAP190" ENSG00000165684 "Small nuclear RNA activating complex polypeptide 4" Q5SXM2 9 136375567-136400176 "Essential proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Respiratory ciliated cells: 39.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028939, HPA046627, HPA073243" Uncertain Approved "Nucleoplasm,Nuclear membrane" No No "Cluster 61: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 34: Ciliated cells - Cilia assembly & function" 13 "Nucleoplasm, Nuclear membrane" "HPA028939: , HPA046627: , HPA073243: " "unprognostic (2.15e-1)" "unprognostic (1.32e-2)" "unprognostic (2.63e-3)" "unprognostic (7.85e-2)" "unprognostic (1.23e-1)" "unprognostic (1.52e-1)" "unprognostic (9.34e-2)" "unprognostic (2.51e-3)" "unprognostic (5.50e-2)" "unprognostic (1.15e-1)" "unprognostic (1.40e-1)" "unprognostic (5.83e-2)" "unprognostic (1.38e-1)" "unprognostic (7.89e-3)" "unprognostic (1.42e-1)" "unprognostic (3.89e-1)" "potential prognostic unfavorable (4.19e-4)" "unprognostic (2.09e-1)" "potential prognostic favorable (7.94e-4)" "unprognostic (1.87e-1)" "unprognostic (3.48e-3)" "unprognostic (1.16e-3)" "unprognostic (1.31e-1)" "unprognostic (9.69e-2)" "unprognostic (4.36e-3)" "unprognostic (1.39e-2)" "unprognostic (2.56e-1)" "unprognostic (6.23e-2)" "unprognostic (7.95e-3)" "unprognostic (9.95e-3)" "unprognostic (1.80e-2)" SNAPC5 SNAP19 ENSG00000174446 "Small nuclear RNA activating complex polypeptide 5" O75971 15 66490135-66497780 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 115.6;Late primary spermatocytes: 142.9;Late spermatids: 128.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024379 Uncertain Supported Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 1: Neurons - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 13 Nucleoplasm "HPA024379: " "unprognostic (3.32e-2)" "unprognostic (4.34e-2)" "unprognostic (1.00e-1)" "unprognostic (6.75e-2)" "unprognostic (8.33e-3)" "unprognostic (2.88e-1)" "unprognostic (5.05e-3)" "unprognostic (2.70e-1)" "unprognostic (2.26e-1)" "unprognostic (9.69e-3)" "unprognostic (3.58e-3)" "unprognostic (2.54e-2)" "unprognostic (3.58e-2)" "unprognostic (4.46e-2)" "unprognostic (1.25e-2)" "unprognostic (3.09e-1)" "unprognostic (1.50e-1)" "unprognostic (1.90e-2)" "unprognostic (1.07e-2)" "unprognostic (2.35e-2)" "unprognostic (4.12e-2)" "unprognostic (2.52e-1)" "unprognostic (9.55e-2)" "unprognostic (3.35e-1)" "unprognostic (9.63e-2)" "unprognostic (6.10e-2)" "unprognostic (1.82e-3)" "unprognostic (7.19e-2)" "unprognostic (1.30e-1)" "unprognostic (6.21e-3)" "unprognostic (2.35e-2)" SNAPIN "BLOC1S7, BORCS3, SNAPAP" ENSG00000143553 "SNAP associated protein" O95295 1 153658703-153661852 "Predicted intracellular proteins, Transporters" "Exocytosis, Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 126.4;Esophageal suprabasal cells: 115.6;Hofbauer cells: 119.8;Megakaryocytes: 111.3;Oocytes: 152.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046974 Approved Approved "Nucleoli,Golgi apparatus" NA NA 16000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 52: Non-specific - Cellular respiration" "Cluster 27: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 97: Non-specific - Cellular respiration" 83 "Golgi apparatus" Nucleoli "HPA046974: " "unprognostic (1.03e-2)" "unprognostic (6.30e-2)" "unprognostic (3.84e-2)" "unprognostic (8.98e-2)" "unprognostic (2.45e-2)" "unprognostic (5.72e-2)" "unprognostic (3.25e-2)" "unprognostic (1.12e-1)" "unprognostic (2.82e-1)" "unprognostic (5.92e-3)" "potential prognostic favorable (8.39e-4)" "unprognostic (1.97e-1)" "unprognostic (2.63e-1)" "unprognostic (2.34e-3)" "unprognostic (2.00e-1)" "unprognostic (2.49e-1)" "unprognostic (2.68e-1)" "unprognostic (2.90e-1)" "unprognostic (3.73e-2)" "unprognostic (9.29e-2)" "unprognostic (1.46e-2)" "unprognostic (4.28e-2)" "unprognostic (2.16e-1)" "unprognostic (1.14e-1)" "unprognostic (5.48e-2)" "unprognostic (1.13e-1)" "unprognostic (5.63e-2)" "unprognostic (1.85e-1)" "unprognostic (8.57e-2)" "unprognostic (1.27e-2)" "unprognostic (2.03e-1)" SNCA "NACP, PARK1, PARK4, PD1" ENSG00000145335 "Synuclein alpha" P37840 4 89700345-89838315 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Alzheimer disease, Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "bone marrow: 257.8;brain: 263.1" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 321.9;Erythrocytes: 920.7;Megakaryocytes: 1366.1;Melanocytes: 876.2;Platelets: 1210.8" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 9 "Skin Cutaneous Melanoma (TCGA): 289.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 103.2" "Group enriched" "Detected in all" 4 "dendritic cells: 103.2;granulocytes: 51.5;monocytes: 67.2" "Cancer enhanced" "Detected in many" "skin cancer: 309.1" "Adipose visceral - Mesothelial cells, Colon - Enteric glia cells, Liver - Erythroid cells, Lung - Fibroblasts_1, Skin - Eccrine sweat gland cells, Spleen - Erythrocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005459, CAB010877" Enhanced "Intracellular and membrane" "No annotated function" NA NA 42000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 304 "CAB010877: , HPA005459: " "unprognostic (2.21e-1)" "unprognostic (7.42e-2)" "unprognostic (1.09e-1)" "unprognostic (4.34e-2)" "unprognostic (3.51e-2)" "unprognostic (1.07e-1)" "unprognostic (1.12e-2)" "unprognostic (4.64e-1)" "unprognostic (1.15e-2)" "unprognostic (7.02e-2)" "unprognostic (3.09e-3)" "unprognostic (1.05e-1)" "unprognostic (2.74e-2)" "unprognostic (1.96e-2)" "unprognostic (1.51e-1)" "unprognostic (4.83e-2)" "unprognostic (1.19e-1)" "unprognostic (6.83e-3)" "unprognostic (1.79e-1)" "potential prognostic favorable (5.69e-4)" "unprognostic (1.02e-2)" "unprognostic (3.39e-2)" "unprognostic (2.17e-1)" "unprognostic (1.14e-2)" "unprognostic (1.06e-1)" "potential prognostic unfavorable (9.75e-4)" "unprognostic (1.02e-1)" "unprognostic (1.20e-3)" "unprognostic (1.14e-1)" SNCAIP SYPH1 ENSG00000064692 "Synuclein alpha interacting protein" Q9Y6H5 5 122311354-122464219 "Disease related genes, Predicted intracellular proteins" "Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 16.1;endometrium 1: 18.2;ovary: 24.6" "Cell type enhanced" "Detected in many" "Astrocytes: 129.3;Bergmann glia: 151.9;Choroid plexus epithelial cells: 256.5;Early spermatids: 151.6;Endometrial secretory cells: 117.3;Endometrial stromal cells: 232.3;Ependymal cells: 432.2;Epicardial cells: 232.0;Lymphatic endothelial cells: 217.4;Mesothelial cells: 172.7;Pituitary stem cells: 297.6" "Cell type enhanced" "Detected in all" "ependymal cell: 493.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 44 "basophil: 7.6" "Lineage enriched" "Detected in single" 44 "granulocytes: 7.6" "Low cancer specificity" "Detected in many" "Skeletal muscle - Fibroblasts, Spleen - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" HPA064687 Uncertain Supported "Nucleoplasm,Cytoplasmic bodies" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 75: Ovary - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 15 "Cytoplasmic bodies" Nucleoplasm "HPA064687: " "unprognostic (1.51e-1)" "unprognostic (1.02e-1)" "unprognostic (3.00e-2)" "unprognostic (1.12e-1)" "unprognostic (8.02e-2)" "unprognostic (3.62e-3)" "unprognostic (1.72e-2)" "unprognostic (1.33e-2)" "unprognostic (2.28e-1)" "unprognostic (8.80e-3)" "unprognostic (3.02e-3)" "unprognostic (2.07e-2)" "unprognostic (7.91e-2)" "unprognostic (1.54e-1)" "unprognostic (1.58e-1)" "unprognostic (4.21e-1)" "unprognostic (1.02e-1)" "unprognostic (4.56e-2)" "unprognostic (8.31e-3)" "unprognostic (4.52e-1)" "unprognostic (2.55e-1)" "unprognostic (1.03e-1)" "unprognostic (7.83e-3)" "unprognostic (1.31e-2)" "unprognostic (2.25e-1)" SNCB ENSG00000074317 "Synuclein beta" Q16143 5 176620082-176630556 "Human disease related genes, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 25 "brain: 562.7;retina: 169.1" "Group enriched" "Detected in some" 4 "Brain excitatory neurons: 71.7;Brain inhibitory neurons: 60.0;Cone photoreceptor cells: 43.5;Oocytes: 50.7;Other brain neurons: 40.8;Retinal amacrine cells: 64.5;Retinal bipolar cells: 69.8;Retinal horizontal cells: 24.0;Rod photoreceptor cells: 50.9" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in some" 8 "Glioblastoma Multiforme (TCGA): 29.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002681, HPA035876" Enhanced Supported NA NA 5400000 "Cluster 27: Cerebellum - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 9 "CAB002681: , HPA035876: " "unprognostic (3.19e-3)" "unprognostic (1.40e-1)" "unprognostic (1.63e-3)" "unprognostic (1.03e-3)" "unprognostic (2.23e-1)" "unprognostic (8.47e-2)" SNCG "BCSG1, persyn, SR" ENSG00000173267 "Synuclein gamma" O76070 10 86958599-86963258 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 300.4;blood vessel: 339.7;brain: 638.1" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 334.1;Breast secretory cells: 292.1;Epididymal basal cells: 396.3;Esophageal apical cells: 708.9;Lymphatic endothelial cells: 440.0;Prostatic club cells: 655.8;Prostatic hillock cells: 570.4;Urothelial cells: 2088.7;Vascular smooth muscle cells: 577.1" "Cell type enhanced" "Detected in all" "hippocampal CA4: 290.1;lower rhombic lip: 535.4" "Group enriched" "Detected in all" 6 "Bladder Urothelial Carcinoma (TCGA): 646.8;Ovary Serous Cystadenocarcinoma (TCGA): 181.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 231.5" "Liver - Vascular endothelial cells" "Region enhanced" "Detected in all" "pons and medulla: 280.0" "Low region specificity" "Detected in many" "CAB001452, HPA014404, CAB040581, CAB080022" Enhanced Supported Supported "Golgi apparatus,Centrosome,Cytosol" NA NA 44000 "Cluster 36: Brain & Liver - Signaling" "Cluster 45: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 69: Urothelial cells - Basic cellular functions" 8 "Golgi apparatus, Centrosome, Cytosol" "CAB001452: , CAB040581: , CAB080022: , HPA014404: " "unprognostic (1.31e-3)" "unprognostic (7.71e-2)" "unprognostic (2.45e-3)" "unprognostic (1.36e-1)" "unprognostic (8.77e-3)" "unprognostic (8.37e-2)" "unprognostic (1.38e-1)" "potential prognostic favorable (6.96e-6)" "unprognostic (1.86e-1)" "unprognostic (1.07e-2)" "unprognostic (1.21e-2)" "unprognostic (5.83e-3)" "unprognostic (2.09e-2)" "unprognostic (6.21e-3)" "unprognostic (5.39e-2)" "unprognostic (2.24e-2)" "unprognostic (7.19e-2)" "unprognostic (1.01e-2)" "unprognostic (1.03e-3)" "unprognostic (1.62e-1)" "unprognostic (9.96e-2)" "validated prognostic unfavorable (1.84e-4)" "validated prognostic unfavorable (8.86e-5)" "unprognostic (3.46e-1)" "unprognostic (1.68e-2)" "unprognostic (2.86e-2)" "unprognostic (2.97e-2)" "potential prognostic unfavorable (9.87e-4)" "unprognostic (1.56e-1)" "unprognostic (5.24e-2)" "potential prognostic unfavorable (4.96e-4)" SND1 "p100, TDRD11" ENSG00000197157 "Staphylococcal nuclease and tudor domain containing 1" Q7KZF4 7 127652194-128092609 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Endonuclease, Hydrolase, Nuclease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002529, HPA002632, CAB019323" Enhanced Enhanced Cytosol NA NA 3600000 "Cluster 13: Non-specific - Mitochondria" "Cluster 70: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 39: Non-specific - Transcription" "Cluster 8: Non-specific - Secretory pathway" 53 Cytosol "CAB019323: , HPA002529: , HPA002632: " "unprognostic (5.96e-2)" "unprognostic (1.50e-1)" "unprognostic (1.19e-1)" "potential prognostic unfavorable (4.64e-4)" "unprognostic (3.68e-2)" "unprognostic (7.15e-2)" "unprognostic (9.95e-2)" "unprognostic (4.80e-1)" "unprognostic (1.91e-1)" "potential prognostic unfavorable (6.79e-4)" "potential prognostic favorable (1.68e-6)" "unprognostic (4.46e-2)" "unprognostic (1.23e-1)" "unprognostic (2.84e-2)" "potential prognostic unfavorable (1.75e-5)" "unprognostic (8.76e-2)" "unprognostic (8.46e-3)" "unprognostic (2.08e-1)" "unprognostic (5.69e-2)" "unprognostic (5.38e-2)" "unprognostic (5.75e-2)" "unprognostic (3.24e-2)" "unprognostic (1.69e-1)" "unprognostic (1.76e-1)" "unprognostic (1.56e-1)" "unprognostic (6.54e-2)" "unprognostic (1.72e-1)" "unprognostic (1.49e-1)" "unprognostic (4.18e-1)" "unprognostic (1.40e-2)" "unprognostic (6.81e-2)" SNED1 "FLJ00133, Snep, SST3" ENSG00000162804 "Sushi, nidogen and EGF like domains 1" Q8TER0 2 240998618-241095568 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bergmann glia: 534.2;Choroid plexus epithelial cells: 542.0;Fibro-adipogenic progenitors: 680.0;Fibroblasts: 503.2;Leydig cells: 1952.0;Myonuclei: 500.1;Myosatellite cells: 1061.7;Peritubular myoid cells: 962.5" "Cell type enhanced" "Detected in all" "Bergmann glia: 569.9;endothelial cell: 606.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.9" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Lung - Fibroblasts_2, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036414, HPA036415" Uncertain "Secreted to blood" "No annotated function" NA NA 21000000 "Cluster 16: Non-specific - Cell proliferation" "Cluster 75: Ovary - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" "HPA036414: , HPA036415: " "unprognostic (5.77e-3)" "unprognostic (2.10e-1)" "unprognostic (4.93e-2)" "unprognostic (1.91e-2)" "unprognostic (6.82e-2)" "unprognostic (4.28e-1)" "unprognostic (9.36e-3)" "unprognostic (2.87e-2)" "unprognostic (6.42e-2)" "unprognostic (1.42e-2)" "validated prognostic favorable (2.20e-6)" "validated prognostic favorable (1.19e-4)" "unprognostic (4.11e-2)" "unprognostic (1.58e-3)" "unprognostic (1.66e-3)" "unprognostic (8.99e-2)" "unprognostic (1.55e-1)" "unprognostic (4.61e-2)" "unprognostic (1.43e-1)" "unprognostic (3.04e-2)" "unprognostic (7.88e-2)" "unprognostic (1.88e-2)" "unprognostic (8.73e-2)" "unprognostic (1.75e-1)" "unprognostic (2.90e-1)" "unprognostic (1.48e-2)" "unprognostic (1.97e-1)" "unprognostic (1.15e-1)" "unprognostic (1.62e-1)" "unprognostic (5.69e-3)" "unprognostic (6.22e-2)" SNF8 "Dot3, EAP30, VPS22" ENSG00000159210 "SNF8 subunit of ESCRT-II" Q96H20 17 48929316-48944842 "Essential proteins, Predicted intracellular proteins" "Protein transport, Transcription, Transcription regulation, Transport" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 480.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059320 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 44 Cytosol Nucleoplasm "HPA059320: " "unprognostic (9.71e-3)" "unprognostic (2.29e-1)" "unprognostic (5.21e-2)" "unprognostic (2.69e-1)" "unprognostic (3.93e-3)" "unprognostic (2.33e-2)" "unprognostic (2.89e-2)" "unprognostic (4.55e-3)" "unprognostic (1.92e-2)" "unprognostic (2.21e-2)" "potential prognostic favorable (4.13e-4)" "unprognostic (2.37e-2)" "unprognostic (2.81e-1)" "validated prognostic unfavorable (1.82e-4)" "validated prognostic unfavorable (2.80e-6)" "unprognostic (2.73e-3)" "unprognostic (1.36e-3)" "unprognostic (2.96e-1)" "unprognostic (3.44e-2)" "unprognostic (1.14e-1)" "unprognostic (3.36e-1)" "unprognostic (2.67e-1)" "unprognostic (4.16e-2)" "unprognostic (1.00e-1)" "unprognostic (6.59e-2)" "unprognostic (1.64e-1)" "unprognostic (1.74e-1)" "unprognostic (5.10e-2)" "unprognostic (1.58e-1)" "unprognostic (5.78e-2)" "unprognostic (1.46e-1)" SNIP1 PML1 ENSG00000163877 "Smad nuclear interacting protein 1" Q8TAD8 1 37534449-37554293 "Disease related genes, Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, RNA-mediated gene silencing" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 106.0;Neutrophils: 107.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036896 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 76: Non-specific - Metabolism" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 37: Non-specific - mRNA processing" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 96 Nucleoplasm Cytosol "HPA036896: " "unprognostic (1.81e-2)" "unprognostic (3.43e-2)" "unprognostic (8.56e-3)" "unprognostic (2.06e-2)" "unprognostic (8.77e-2)" "unprognostic (1.62e-1)" "unprognostic (2.11e-1)" "unprognostic (9.61e-2)" "unprognostic (1.73e-1)" "unprognostic (4.48e-2)" "validated prognostic favorable (3.66e-5)" "validated prognostic favorable (2.34e-4)" "unprognostic (8.90e-2)" "unprognostic (2.60e-2)" "unprognostic (4.32e-2)" "unprognostic (2.23e-1)" "unprognostic (3.69e-1)" "unprognostic (1.67e-1)" "unprognostic (1.15e-1)" "unprognostic (4.25e-3)" "unprognostic (2.55e-2)" "unprognostic (5.82e-2)" "unprognostic (5.26e-2)" "potential prognostic unfavorable (5.97e-4)" "unprognostic (3.11e-2)" "unprognostic (3.99e-2)" "unprognostic (7.21e-2)" "unprognostic (7.02e-3)" "unprognostic (1.30e-1)" "unprognostic (7.00e-2)" "unprognostic (7.87e-2)" SNN ENSG00000184602 Stannin O75324 16 11668455-11679152 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 168.3;skeletal muscle: 111.2" "Cell type enriched" "Detected in many" 5 "Platelets: 651.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 100.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in all" 5 "Gallbladder cancer: 123.0" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011055 Approved Uncertain Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 47: Platelets - Hemostasis" 1 Cytosol "HPA011055: " "unprognostic (2.26e-2)" "unprognostic (1.05e-1)" "unprognostic (3.31e-1)" "unprognostic (1.59e-1)" "unprognostic (3.35e-1)" "unprognostic (2.42e-1)" "unprognostic (1.40e-1)" "unprognostic (1.66e-1)" "unprognostic (1.67e-2)" "unprognostic (1.50e-1)" "potential prognostic favorable (3.27e-7)" "unprognostic (6.06e-2)" "unprognostic (1.53e-2)" "potential prognostic unfavorable (1.77e-6)" "unprognostic (1.33e-1)" "unprognostic (7.84e-3)" "unprognostic (2.19e-2)" "unprognostic (1.73e-3)" "unprognostic (8.63e-2)" "unprognostic (1.88e-1)" "unprognostic (1.46e-1)" "unprognostic (2.48e-2)" "unprognostic (7.22e-3)" "unprognostic (2.12e-1)" "unprognostic (1.43e-1)" "unprognostic (1.57e-1)" "unprognostic (1.64e-1)" "unprognostic (3.46e-2)" "unprognostic (4.61e-1)" "unprognostic (1.01e-1)" "unprognostic (6.60e-3)" SNORC "ASCL830, C2orf82, UNQ830" ENSG00000182600 "Secondary ossification center associated regulator of chondrocyte maturation" Q6UX34 2 232857270-232878708 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 88.1;skin 1: 31.3" "Cell type enriched" "Detected in many" 6 "Breast secretory cells: 947.1" "Cell type enhanced" "Detected in all" "astrocyte: 87.0" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 33.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 19 "basophil: 2.5" "Lineage enriched" "Detected in single" 19 "granulocytes: 2.5" "Cancer enhanced" "Detected in many" "breast cancer: 7.9" "Breast - Breast glandular cells (progenitors), Liver - Hepatocytes, Skin - Eccrine sweat gland cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA052824 Approved Approved Nucleoplasm,Nucleoli "Intracellular and membrane" "No annotated function" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 22: Non-specific - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 20 "Nucleoplasm, Nucleoli" "HPA052824: " "unprognostic (5.22e-2)" "unprognostic (1.38e-2)" "unprognostic (6.22e-2)" "unprognostic (7.55e-2)" "unprognostic (2.04e-1)" "unprognostic (1.30e-1)" "unprognostic (1.24e-1)" "unprognostic (1.02e-2)" "validated prognostic unfavorable (4.87e-5)" "validated prognostic unfavorable (5.58e-4)" "unprognostic (2.93e-1)" "unprognostic (7.59e-2)" "unprognostic (2.05e-2)" "unprognostic (3.86e-1)" "unprognostic (1.67e-2)" "unprognostic (1.19e-1)" "unprognostic (4.38e-3)" "unprognostic (1.70e-1)" "unprognostic (2.45e-2)" "unprognostic (1.28e-1)" "unprognostic (9.13e-2)" "potential prognostic unfavorable (4.28e-4)" "unprognostic (1.10e-3)" "unprognostic (7.44e-2)" "unprognostic (9.25e-2)" SNPH bA314N13.5 ENSG00000101298 Syntaphilin O15079 20 1266280-1309328 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 72.8" "Cell type enhanced" "Detected in many" "Astrocytes: 21.2;Brain excitatory neurons: 20.9;Brain inhibitory neurons: 23.6;Breast lactating cells: 11.8;Early spermatids: 13.0;Oligodendrocyte progenitor cells: 20.9;Other brain neurons: 19.7;Retinal amacrine cells: 13.7;Retinal bipolar cells: 14.5;Retinal horizontal cells: 20.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 1.0;naive CD8 T-cell: 1.0" "Lineage enriched" "Detected in single" 9 "T-cells: 1.0" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049393 Approved Uncertain "Cytokinetic bridge,Mitochondria" Yes No "Cluster 43: Non-specific - Transcription & Translation" "Cluster 78: Brain - Neuronal signaling" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 109: Neurons - Neuronal signaling" 5 Mitochondria "Cytokinetic bridge" "HPA049393: " "unprognostic (7.07e-2)" "unprognostic (4.34e-2)" "unprognostic (1.83e-1)" "unprognostic (1.12e-2)" "unprognostic (6.81e-2)" "unprognostic (1.46e-1)" "unprognostic (3.09e-2)" "unprognostic (2.15e-1)" "unprognostic (2.74e-1)" "unprognostic (1.33e-2)" "unprognostic (1.92e-1)" "unprognostic (2.44e-1)" "potential prognostic favorable (7.31e-5)" "unprognostic (9.87e-2)" "unprognostic (3.79e-3)" "unprognostic (9.91e-2)" "potential prognostic favorable (4.28e-4)" "unprognostic (5.74e-2)" "unprognostic (1.31e-1)" "unprognostic (5.33e-2)" "unprognostic (2.71e-1)" "unprognostic (1.86e-1)" "unprognostic (3.76e-2)" "unprognostic (9.82e-2)" "unprognostic (1.67e-1)" "unprognostic (3.17e-2)" SNRK "FLJ20224, HSNFRK, KIAA0096" ENSG00000163788 "SNF related kinase" Q9NRH2 3 43286512-43424764 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Loop of henle epithelial cells: 274.5;Neutrophil progenitors: 301.2;Neutrophils: 827.5" "Cell type enhanced" "Detected in all" "pericyte: 901.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adrenal gland - Endothelial cells, Breast - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Spleen - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042163 Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 35: Non-specific - DNA binding" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 4 "Vesicles, Plasma membrane, Cell Junctions" Nucleoplasm "HPA042163: " "unprognostic (1.60e-3)" "unprognostic (1.03e-1)" "unprognostic (1.65e-1)" "unprognostic (7.34e-2)" "unprognostic (1.76e-1)" "unprognostic (1.41e-2)" "unprognostic (1.11e-1)" "potential prognostic favorable (6.11e-5)" "potential prognostic favorable (3.01e-4)" "unprognostic (4.70e-2)" "validated prognostic favorable (3.29e-10)" "validated prognostic favorable (8.40e-5)" "unprognostic (5.27e-3)" "unprognostic (1.39e-1)" "unprognostic (2.04e-2)" "unprognostic (3.53e-2)" "unprognostic (1.59e-1)" "unprognostic (3.98e-2)" "unprognostic (1.20e-1)" "unprognostic (2.43e-1)" "unprognostic (1.01e-2)" "unprognostic (2.81e-1)" "unprognostic (9.20e-2)" "unprognostic (1.31e-1)" "unprognostic (1.94e-1)" "unprognostic (2.45e-2)" "unprognostic (1.84e-2)" "unprognostic (6.53e-2)" "unprognostic (4.60e-1)" "unprognostic (1.53e-2)" "unprognostic (2.92e-1)" SNRNP200 "ASCC3L1, BRR2, HELIC2, KIAA0788, RP33, U5-200KD" ENSG00000144028 "Small nuclear ribonucleoprotein U5 subunit 200" O75643 2 96274338-96321271 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029321 Approved Supported "Nucleoplasm,Primary cilium,Cytosol" NA NA 290000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 17: Non-specific - RNA processing" 177 Nucleoplasm "Primary cilium, Cytosol" "HPA029321: " "unprognostic (5.74e-2)" "unprognostic (2.56e-2)" "unprognostic (1.67e-1)" "unprognostic (2.17e-2)" "unprognostic (1.58e-1)" "unprognostic (8.68e-2)" "unprognostic (1.87e-2)" "unprognostic (2.95e-1)" "unprognostic (7.87e-2)" "potential prognostic unfavorable (8.40e-7)" "validated prognostic favorable (2.19e-7)" "validated prognostic favorable (1.87e-4)" "unprognostic (4.79e-1)" "unprognostic (5.34e-2)" "unprognostic (4.92e-3)" "unprognostic (8.79e-2)" "unprognostic (1.08e-2)" "unprognostic (2.37e-2)" "unprognostic (6.41e-2)" "unprognostic (2.54e-2)" "unprognostic (9.12e-2)" "unprognostic (5.78e-2)" "unprognostic (3.11e-2)" "unprognostic (1.23e-1)" "unprognostic (2.78e-2)" "unprognostic (7.41e-3)" "unprognostic (1.68e-1)" "unprognostic (7.49e-2)" "unprognostic (2.80e-1)" "unprognostic (1.71e-3)" "unprognostic (1.56e-1)" SNRNP25 "C16orf33, U11/U12-25K" ENSG00000161981 "Small nuclear ribonucleoprotein U11/U12 subunit 25" Q9BV90 16 53828-57669 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 123.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 151.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 220.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Stomach - Mitotic cells (Stomach), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041183, HPA044248" Uncertain Supported "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes No "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 27: Non-specific - Cell proliferation" 21 Nucleoplasm "Cytokinetic bridge, Cytosol" "HPA041183: , HPA044248: " "unprognostic (1.06e-2)" "unprognostic (1.81e-2)" "unprognostic (8.91e-2)" "potential prognostic favorable (7.40e-6)" "unprognostic (1.21e-2)" "unprognostic (2.22e-2)" "unprognostic (4.29e-1)" "unprognostic (5.23e-2)" "unprognostic (8.33e-2)" "unprognostic (2.86e-2)" "unprognostic (7.08e-2)" "unprognostic (1.13e-2)" "unprognostic (6.67e-2)" "unprognostic (2.80e-2)" "potential prognostic unfavorable (1.47e-4)" "unprognostic (3.72e-2)" "unprognostic (6.99e-3)" "unprognostic (2.28e-2)" "unprognostic (1.92e-1)" "unprognostic (2.00e-1)" "unprognostic (8.33e-3)" "unprognostic (1.05e-2)" "unprognostic (6.55e-1)" "unprognostic (2.00e-1)" "unprognostic (1.89e-1)" "unprognostic (9.15e-2)" "unprognostic (7.15e-2)" "unprognostic (2.32e-2)" "unprognostic (1.65e-1)" "unprognostic (1.18e-1)" "unprognostic (9.59e-2)" SNRNP27 "RY1, U4/U6.U5-27K" ENSG00000124380 "Small nuclear ribonucleoprotein U4/U6.U5 subunit 27" Q8WVK2 2 69893956-69905575 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Tuft cells: 161.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034541 Approved Approved Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 17: Non-specific - RNA processing" 13 Nucleoplasm "HPA034541: " "unprognostic (1.30e-1)" "unprognostic (5.00e-2)" "unprognostic (1.13e-1)" "unprognostic (4.33e-2)" "unprognostic (2.48e-2)" "unprognostic (1.53e-1)" "unprognostic (1.80e-1)" "unprognostic (2.34e-1)" "unprognostic (2.89e-3)" "unprognostic (2.43e-3)" "unprognostic (1.61e-3)" "unprognostic (2.09e-1)" "unprognostic (2.34e-1)" "unprognostic (1.01e-3)" "unprognostic (1.29e-3)" "unprognostic (4.95e-3)" "unprognostic (8.54e-2)" "unprognostic (1.02e-1)" "unprognostic (1.35e-1)" "unprognostic (7.15e-2)" "potential prognostic unfavorable (1.10e-4)" "unprognostic (3.16e-1)" "potential prognostic unfavorable (7.02e-4)" "unprognostic (4.45e-1)" "unprognostic (6.86e-2)" "unprognostic (5.90e-3)" "potential prognostic unfavorable (4.74e-4)" "unprognostic (5.71e-2)" "unprognostic (2.27e-1)" "unprognostic (1.72e-2)" "unprognostic (2.92e-2)" SNRNP35 U1SNRNPBP ENSG00000184209 "Small nuclear ribonucleoprotein U11/U12 subunit 35" Q16560 12 123458088-123473154 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 159.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059145, HPA067031" Supported Supported Nucleoli NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 38: Non-specific - Transcription" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 6 Nucleoli "HPA059145: , HPA067031: " "unprognostic (7.85e-2)" "unprognostic (9.49e-2)" "unprognostic (6.57e-3)" "potential prognostic unfavorable (7.28e-4)" "unprognostic (2.52e-1)" "unprognostic (6.25e-2)" "unprognostic (1.71e-1)" "unprognostic (1.78e-1)" "unprognostic (1.71e-1)" "unprognostic (1.11e-1)" "potential prognostic unfavorable (7.25e-4)" "potential prognostic favorable (1.32e-4)" "potential prognostic favorable (8.15e-4)" "unprognostic (5.94e-3)" "unprognostic (1.89e-1)" "unprognostic (2.83e-1)" "unprognostic (1.20e-1)" "unprognostic (6.42e-2)" "unprognostic (9.05e-2)" "unprognostic (1.72e-1)" "unprognostic (1.79e-2)" "unprognostic (3.62e-3)" "unprognostic (2.67e-1)" "unprognostic (3.12e-1)" "unprognostic (4.47e-1)" "unprognostic (3.26e-1)" "unprognostic (2.43e-1)" "unprognostic (5.97e-2)" "unprognostic (6.99e-2)" "unprognostic (1.41e-2)" "potential prognostic favorable (5.59e-4)" SNRNP40 "HPRP8BP, PRP8BP, PRPF8BP, SPF38, WDR57" ENSG00000060688 "Small nuclear ribonucleoprotein U5 subunit 40" Q96DI7 1 31259568-31296788 "Essential proteins, Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early primary spermatocytes: 164.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026527, HPA027345" Supported Supported "Nuclear speckles" NA NA 14000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 39: Testis - Nuclear processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 184 "Nuclear speckles" "HPA026527: , HPA027345: " "unprognostic (1.06e-1)" "unprognostic (1.47e-1)" "unprognostic (3.91e-3)" "unprognostic (2.14e-1)" "potential prognostic favorable (1.79e-4)" "unprognostic (2.20e-1)" "unprognostic (2.84e-2)" "unprognostic (2.05e-3)" "unprognostic (5.57e-2)" "unprognostic (9.38e-2)" "potential prognostic favorable (1.10e-5)" "unprognostic (1.86e-1)" "unprognostic (2.99e-2)" "potential prognostic unfavorable (1.13e-6)" "unprognostic (6.09e-3)" "unprognostic (1.33e-1)" "unprognostic (1.20e-2)" "unprognostic (4.45e-2)" "unprognostic (5.34e-3)" "unprognostic (1.58e-1)" "unprognostic (6.48e-2)" "unprognostic (1.54e-1)" "unprognostic (7.56e-2)" "unprognostic (7.28e-2)" "unprognostic (4.71e-2)" "unprognostic (2.93e-2)" "unprognostic (3.66e-2)" "unprognostic (1.70e-1)" "unprognostic (3.55e-1)" "unprognostic (1.96e-1)" "unprognostic (2.18e-2)" SNRNP48 "C6orf151, dJ336K20B.1, dJ512B11.2, FLJ32234" ENSG00000168566 "Small nuclear ribonucleoprotein U11/U12 subunit 48" Q6IEG0 6 7590198-7611967 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029234 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" 15 Nucleoplasm Cytosol "HPA029234: " "unprognostic (5.59e-1)" "unprognostic (1.68e-3)" "unprognostic (2.31e-1)" "unprognostic (2.01e-2)" "unprognostic (3.23e-2)" "unprognostic (1.02e-1)" "unprognostic (2.93e-2)" "unprognostic (7.90e-2)" "unprognostic (1.79e-1)" "potential prognostic unfavorable (3.72e-4)" "potential prognostic favorable (1.26e-4)" "unprognostic (3.26e-3)" "unprognostic (2.33e-1)" "unprognostic (1.29e-2)" "unprognostic (6.13e-2)" "unprognostic (1.20e-1)" "unprognostic (1.94e-1)" "unprognostic (1.33e-1)" "unprognostic (4.36e-3)" "unprognostic (4.38e-2)" "unprognostic (1.04e-1)" "unprognostic (1.44e-1)" "unprognostic (3.10e-2)" "unprognostic (1.18e-1)" "unprognostic (5.92e-3)" "unprognostic (3.20e-1)" "unprognostic (4.28e-2)" "unprognostic (2.92e-1)" "unprognostic (3.57e-1)" "unprognostic (1.02e-1)" "unprognostic (1.73e-1)" SNRNP70 "RNPU1Z, RPU1, Snp1, SNRP70, U1-70K" ENSG00000104852 "Small nuclear ribonucleoprotein U1 subunit 70" P08621 19 49085419-49108605 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001718, HPA042050, HPA043516" Supported Enhanced Nucleoplasm NA NA 8300 "Cluster 22: Eosinophils - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 35: RS4;11 - Unknown function" "Cluster 17: Non-specific - RNA processing" 206 Nucleoplasm "CAB001718: , HPA042050: , HPA043516: " "unprognostic (3.48e-1)" "unprognostic (1.45e-2)" "unprognostic (2.06e-1)" "unprognostic (1.75e-2)" "unprognostic (2.26e-1)" "unprognostic (1.28e-1)" "unprognostic (8.13e-2)" "unprognostic (1.18e-1)" "unprognostic (3.86e-2)" "unprognostic (1.56e-1)" "unprognostic (1.66e-3)" "unprognostic (4.36e-2)" "unprognostic (9.04e-2)" "potential prognostic unfavorable (9.91e-4)" "unprognostic (4.17e-2)" "validated prognostic unfavorable (3.37e-4)" "validated prognostic unfavorable (4.26e-4)" "unprognostic (2.40e-2)" "unprognostic (3.19e-2)" "unprognostic (1.13e-1)" "unprognostic (3.96e-3)" "unprognostic (1.58e-1)" "unprognostic (2.11e-3)" "unprognostic (3.08e-2)" "unprognostic (1.04e-1)" "unprognostic (6.73e-2)" "unprognostic (1.76e-1)" "unprognostic (1.86e-2)" "unprognostic (1.17e-1)" "unprognostic (1.09e-2)" "unprognostic (6.84e-2)" SNRPA "Mud1, U1-A, U1A" ENSG00000077312 "Small nuclear ribonucleoprotein polypeptide A" P09012 19 40750637-40765389 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004652, HPA046440, HPA054834" Supported Supported Nucleoplasm NA NA 76000 "Cluster 13: Non-specific - Mitochondria" "Cluster 64: Non-specific - Transcription" "Cluster 46: Brainstem - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 456 Nucleoplasm "CAB004652: , HPA046440: , HPA054834: " "unprognostic (1.72e-1)" "unprognostic (1.33e-1)" "unprognostic (5.93e-2)" "unprognostic (1.31e-1)" "unprognostic (5.40e-2)" "unprognostic (1.06e-1)" "unprognostic (1.25e-1)" "unprognostic (2.46e-2)" "unprognostic (2.44e-1)" "unprognostic (2.39e-1)" "potential prognostic unfavorable (3.62e-5)" "unprognostic (2.08e-3)" "unprognostic (2.21e-2)" "potential prognostic unfavorable (2.08e-6)" "unprognostic (6.81e-3)" "validated prognostic unfavorable (1.33e-4)" "validated prognostic unfavorable (2.19e-4)" "potential prognostic favorable (3.90e-4)" "unprognostic (2.88e-2)" "unprognostic (1.61e-1)" "unprognostic (1.91e-2)" "unprognostic (1.36e-1)" "unprognostic (1.19e-1)" "unprognostic (4.79e-2)" "unprognostic (6.78e-2)" "unprognostic (3.07e-2)" "unprognostic (5.92e-2)" "unprognostic (4.64e-2)" "unprognostic (3.51e-1)" "unprognostic (7.17e-2)" "unprognostic (1.43e-2)" SNRPA1 "Lea1, U2A'" ENSG00000131876 "Small nuclear ribonucleoprotein polypeptide A'" P09661 15 101281510-101295282 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 165.4;Late primary spermatocytes: 323.0;Migrating cytotrophoblasts: 174.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045622, HPA048499" Supported Supported "Nucleoplasm,Nuclear speckles,Nuclear bodies" NA NA 96000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 168 Nucleoplasm "Nuclear speckles, Nuclear bodies" "HPA045622: , HPA048499: " "unprognostic (1.06e-2)" "unprognostic (6.33e-2)" "unprognostic (3.24e-1)" "unprognostic (2.57e-2)" "unprognostic (3.02e-1)" "unprognostic (1.28e-1)" "unprognostic (2.45e-2)" "unprognostic (7.04e-2)" "unprognostic (1.67e-3)" "unprognostic (6.05e-2)" "unprognostic (2.10e-3)" "unprognostic (1.58e-3)" "potential prognostic unfavorable (1.28e-6)" "validated prognostic unfavorable (8.19e-6)" "validated prognostic unfavorable (4.83e-5)" "potential prognostic unfavorable (9.18e-5)" "unprognostic (2.91e-3)" "unprognostic (3.79e-2)" "unprognostic (2.86e-2)" "unprognostic (9.12e-3)" "unprognostic (1.59e-2)" "unprognostic (3.40e-3)" "potential prognostic unfavorable (1.19e-5)" "unprognostic (2.55e-2)" "unprognostic (7.46e-2)" "unprognostic (1.53e-1)" "unprognostic (2.74e-2)" "unprognostic (1.02e-1)" "unprognostic (2.83e-1)" "unprognostic (2.24e-1)" "unprognostic (1.88e-1)" SNRPB "COD, Sm-B/B', SmB/SmB', snRNP-B, SNRPB1" ENSG00000125835 "Small nuclear ribonucleoprotein polypeptides B and B1" P14678 20 2461634-2470853 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 669.5;Extravillous trophoblasts: 752.0;Migrating cytotrophoblasts: 608.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003482, CAB009610, HPA067842" Approved Supported Nucleoplasm NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 17: Non-specific - RNA processing" 435 Nucleoplasm "CAB009610: , HPA003482: , HPA067842: " "unprognostic (8.56e-2)" "unprognostic (2.40e-1)" "unprognostic (6.09e-2)" "potential prognostic favorable (3.53e-4)" "unprognostic (2.37e-2)" "unprognostic (1.00e-1)" "unprognostic (2.51e-1)" "unprognostic (6.84e-2)" "unprognostic (1.69e-1)" "unprognostic (1.82e-1)" "unprognostic (1.12e-3)" "potential prognostic unfavorable (6.38e-5)" "unprognostic (1.65e-2)" "validated prognostic unfavorable (5.49e-7)" "validated prognostic unfavorable (1.30e-8)" "unprognostic (4.02e-3)" "unprognostic (7.66e-2)" "unprognostic (2.06e-2)" "unprognostic (1.58e-1)" "unprognostic (2.16e-1)" "unprognostic (3.65e-2)" "unprognostic (2.51e-2)" "unprognostic (9.65e-2)" "unprognostic (3.43e-2)" "unprognostic (9.35e-2)" "unprognostic (3.42e-2)" "unprognostic (1.11e-1)" "unprognostic (2.34e-1)" "unprognostic (1.22e-1)" "unprognostic (1.45e-1)" "unprognostic (2.53e-1)" SNRPB2 "Msl1, U2B''" ENSG00000125870 "Small nuclear ribonucleoprotein polypeptide B2" P08579 20 16729961-16742564 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 386.2;Migrating cytotrophoblasts: 380.9;Oocytes: 548.0;Syncytiotrophoblasts: 487.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050814, HPA076104" Supported Supported "Nuclear speckles,Cytoplasmic bodies" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 21: Non-specific - Metabolism" "Cluster 69: Skin cancer - ECM organization" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 212 "Nuclear speckles" "Cytoplasmic bodies" "HPA050814: , HPA076104: " "unprognostic (4.88e-2)" "unprognostic (1.21e-3)" "unprognostic (1.10e-2)" "unprognostic (3.16e-2)" "unprognostic (9.46e-2)" "unprognostic (6.09e-2)" "unprognostic (8.96e-3)" "unprognostic (2.56e-2)" "unprognostic (2.49e-3)" "unprognostic (4.01e-3)" "unprognostic (7.76e-3)" "unprognostic (1.05e-1)" "unprognostic (3.43e-3)" "validated prognostic unfavorable (3.65e-6)" "validated prognostic unfavorable (5.73e-5)" "unprognostic (5.08e-3)" "unprognostic (3.20e-3)" "unprognostic (9.65e-2)" "unprognostic (7.22e-2)" "unprognostic (7.55e-2)" "unprognostic (3.82e-1)" "potential prognostic unfavorable (3.73e-4)" "unprognostic (3.82e-2)" "unprognostic (1.26e-1)" "unprognostic (6.75e-2)" "unprognostic (1.39e-2)" "unprognostic (1.30e-1)" "unprognostic (9.34e-2)" "unprognostic (1.88e-1)" "unprognostic (7.01e-2)" "unprognostic (6.91e-2)" SNRPC "U1-C, Yhc1" ENSG00000124562 "Small nuclear ribonucleoprotein polypeptide C" P09234 6 34757505-34773857 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 281.3;Hofbauer cells: 330.8;Late primary spermatocytes: 737.0;Migrating cytotrophoblasts: 278.3;Oocytes: 303.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034338, HPA042419, HPA055490" Supported Enhanced Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 28: Non-specific - Nuclear processes" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 402 Nucleoplasm "CAB034338: , HPA042419: , HPA055490: " "unprognostic (3.75e-2)" "unprognostic (1.23e-2)" "unprognostic (3.33e-2)" "unprognostic (1.59e-1)" "unprognostic (1.99e-1)" "unprognostic (2.04e-1)" "unprognostic (3.38e-1)" "unprognostic (2.41e-1)" "unprognostic (1.91e-2)" "unprognostic (1.39e-3)" "unprognostic (3.87e-2)" "unprognostic (1.83e-1)" "unprognostic (1.97e-2)" "validated prognostic unfavorable (3.08e-5)" "validated prognostic unfavorable (7.91e-5)" "unprognostic (8.38e-3)" "unprognostic (2.17e-2)" "unprognostic (4.67e-3)" "unprognostic (3.50e-2)" "unprognostic (5.83e-3)" "unprognostic (1.16e-1)" "unprognostic (1.02e-2)" "unprognostic (2.12e-1)" "unprognostic (1.99e-2)" "unprognostic (4.86e-2)" "unprognostic (1.59e-1)" "unprognostic (4.67e-3)" "unprognostic (3.32e-2)" "unprognostic (1.96e-1)" "unprognostic (2.42e-1)" "unprognostic (1.66e-1)" SNRPD1 "HsT2456, Sm-D1, SNRPD" ENSG00000167088 "Small nuclear ribonucleoprotein D1 polypeptide" P62314 18 21612314-21633524 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" Ribonucleoprotein "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 483.6;Esophageal basal cells: 554.5;Extravillous trophoblasts: 616.8;Gastric progenitor cells: 528.0;Migrating cytotrophoblasts: 638.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040516 Supported NA NA 240000 "Cluster 13: Non-specific - Mitochondria" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 25: Non-specific - Transcription" "Cluster 25: Non-specific - Ribosome" "Cluster 27: Non-specific - Cell proliferation" 139 "HPA040516: " "unprognostic (1.69e-3)" "unprognostic (8.00e-2)" "unprognostic (4.69e-1)" "unprognostic (1.42e-2)" "unprognostic (6.77e-2)" "unprognostic (1.51e-1)" "unprognostic (2.59e-2)" "unprognostic (1.18e-2)" "unprognostic (1.08e-1)" "unprognostic (5.14e-3)" "unprognostic (5.54e-2)" "unprognostic (5.36e-2)" "unprognostic (5.70e-2)" "validated prognostic unfavorable (6.29e-6)" "validated prognostic unfavorable (9.74e-8)" "unprognostic (3.05e-3)" "unprognostic (2.85e-2)" "unprognostic (2.23e-2)" "unprognostic (5.05e-2)" "potential prognostic favorable (2.36e-4)" "unprognostic (1.88e-1)" "potential prognostic unfavorable (6.16e-4)" "unprognostic (2.42e-2)" "unprognostic (3.00e-2)" "unprognostic (3.46e-1)" "unprognostic (1.50e-1)" "unprognostic (9.17e-3)" "unprognostic (6.65e-2)" "unprognostic (4.79e-1)" "unprognostic (2.02e-1)" "unprognostic (3.37e-1)" SNRPD2 "Sm-D2, SNRPD1" ENSG00000125743 "Small nuclear ribonucleoprotein D2 polypeptide" P62316 19 45687460-45692569 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" Ribonucleoprotein "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 919.0;Esophageal basal cells: 1041.9;Extravillous trophoblasts: 931.3;Late spermatids: 1768.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041437 Supported Supported Cytosol NA NA 16000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 54: Non-specific - Ribosome" "Cluster 27: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 15: Non-specific - Protein processing" 251 Cytosol "HPA041437: " "unprognostic (1.28e-1)" "unprognostic (2.36e-1)" "unprognostic (1.67e-1)" "unprognostic (2.77e-1)" "unprognostic (8.25e-2)" "unprognostic (5.55e-2)" "unprognostic (1.50e-1)" "unprognostic (1.04e-1)" "unprognostic (2.02e-2)" "unprognostic (1.13e-2)" "unprognostic (1.87e-3)" "unprognostic (6.61e-3)" "potential prognostic unfavorable (2.65e-6)" "validated prognostic unfavorable (2.83e-5)" "validated prognostic unfavorable (8.95e-8)" "potential prognostic unfavorable (6.80e-4)" "unprognostic (1.81e-2)" "unprognostic (1.08e-2)" "unprognostic (1.17e-1)" "unprognostic (1.84e-1)" "unprognostic (3.28e-2)" "unprognostic (3.95e-1)" "unprognostic (2.96e-1)" "unprognostic (1.02e-1)" "unprognostic (5.23e-2)" "unprognostic (6.22e-2)" "unprognostic (2.14e-2)" "unprognostic (4.06e-2)" "unprognostic (5.01e-2)" "unprognostic (6.36e-2)" "unprognostic (2.70e-1)" SNRPD3 "Sm-D3, SMD3" ENSG00000100028 "Small nuclear ribonucleoprotein D3 polypeptide" P62318 22 24555958-24582052 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 55.2;Enteric stem cells: 67.1;Enteric transient amplifying cells: 85.0;Enterocytes: 106.2;Epididymal efferent duct absorptive cells: 52.4;Fallopian secretory cells: 51.9;Fallopian tube ciliated cells: 58.4;Gastric progenitor cells: 83.3;Goblet cells: 49.3;Paneth cells: 58.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001170 Supported Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 21000 "Cluster 29: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 66: Non-specific - Mitochondria" "Cluster 15: Non-specific - Protein processing" 101 Nucleoplasm "Nuclear bodies, Cytosol" "HPA001170: " "unprognostic (3.71e-1)" "unprognostic (3.75e-2)" "unprognostic (1.64e-2)" "unprognostic (1.22e-2)" "unprognostic (3.69e-2)" "unprognostic (2.36e-2)" "unprognostic (1.74e-2)" "unprognostic (1.51e-1)" "unprognostic (7.45e-2)" "unprognostic (5.81e-3)" "potential prognostic favorable (3.14e-8)" "unprognostic (1.80e-3)" "unprognostic (2.28e-1)" "unprognostic (9.24e-2)" "unprognostic (1.11e-3)" "unprognostic (9.01e-2)" "unprognostic (1.64e-1)" "unprognostic (1.36e-1)" "potential prognostic favorable (1.57e-4)" "unprognostic (9.88e-3)" "unprognostic (1.33e-1)" "unprognostic (9.46e-2)" "unprognostic (1.05e-1)" "unprognostic (3.63e-1)" "unprognostic (1.77e-3)" "unprognostic (1.02e-1)" "unprognostic (7.10e-3)" "unprognostic (9.88e-2)" "unprognostic (2.38e-1)" "unprognostic (1.96e-1)" "unprognostic (1.83e-2)" SNRPE Sm-E ENSG00000182004 "Small nuclear ribonucleoprotein polypeptide E" P62304 1 203861599-203871152 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 571.0;Gastric progenitor cells: 660.1;Migrating cytotrophoblasts: 652.8;Oocytes: 506.6" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 212.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 370000 "Cluster 33: Non-specific - ATP binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 97: Non-specific - Cellular respiration" 218 "unprognostic (1.02e-2)" "unprognostic (2.08e-1)" "unprognostic (1.51e-2)" "unprognostic (5.69e-2)" "unprognostic (1.56e-2)" "unprognostic (1.34e-2)" "unprognostic (1.81e-1)" "unprognostic (2.79e-2)" "unprognostic (4.70e-2)" "unprognostic (9.08e-2)" "unprognostic (3.82e-1)" "potential prognostic unfavorable (4.65e-4)" "unprognostic (4.22e-3)" "potential prognostic unfavorable (3.15e-4)" "unprognostic (1.87e-3)" "unprognostic (1.70e-2)" "unprognostic (5.83e-3)" "unprognostic (4.87e-3)" "unprognostic (2.71e-2)" "unprognostic (7.63e-2)" "unprognostic (1.40e-3)" "unprognostic (5.32e-2)" "unprognostic (4.44e-2)" "unprognostic (1.37e-2)" "unprognostic (7.28e-2)" "unprognostic (8.48e-2)" "unprognostic (1.41e-1)" "unprognostic (1.33e-1)" "unprognostic (1.15e-1)" "unprognostic (1.97e-3)" "unprognostic (2.97e-1)" SNRPF Sm-F ENSG00000139343 "Small nuclear ribonucleoprotein polypeptide F" P62306 12 95858952-95903828 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 643.8;Extravillous trophoblasts: 522.3;Gastric progenitor cells: 610.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 51000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 446 "unprognostic (2.38e-1)" "unprognostic (2.11e-1)" "unprognostic (1.42e-1)" "unprognostic (5.00e-3)" "unprognostic (1.78e-1)" "unprognostic (2.23e-1)" "unprognostic (5.25e-2)" "unprognostic (2.03e-1)" "unprognostic (7.57e-3)" "unprognostic (2.79e-1)" "potential prognostic unfavorable (3.94e-4)" "unprognostic (5.34e-3)" "unprognostic (1.42e-2)" "unprognostic (1.12e-2)" "potential prognostic unfavorable (3.72e-5)" "potential prognostic unfavorable (1.19e-4)" "unprognostic (8.45e-3)" "unprognostic (2.62e-1)" "unprognostic (1.08e-2)" "unprognostic (2.27e-1)" "unprognostic (1.19e-1)" "unprognostic (7.52e-2)" "unprognostic (7.36e-2)" "unprognostic (4.12e-2)" "unprognostic (1.48e-2)" "unprognostic (3.72e-2)" "unprognostic (9.43e-2)" "unprognostic (1.28e-1)" "unprognostic (3.28e-2)" "unprognostic (3.44e-1)" "unprognostic (2.59e-1)" SNRPG Sm-G ENSG00000143977 "Small nuclear ribonucleoprotein polypeptide G" P62308 2 70281362-70293740 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 670.2;Extravillous trophoblasts: 802.3;Migrating cytotrophoblasts: 786.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064152, HPA067814" Supported Approved Nucleoplasm NA NA 52000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 76: Non-specific - Metabolism" "Cluster 55: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 27: Non-specific - Cell proliferation" 52 Nucleoplasm "HPA064152: , HPA067814: " "unprognostic (1.12e-2)" "unprognostic (8.75e-3)" "unprognostic (3.52e-1)" "unprognostic (1.07e-3)" "unprognostic (7.62e-2)" "unprognostic (2.60e-1)" "unprognostic (3.12e-1)" "unprognostic (4.05e-1)" "potential prognostic unfavorable (4.99e-4)" "unprognostic (8.43e-3)" "unprognostic (1.93e-2)" "unprognostic (1.91e-2)" "unprognostic (2.55e-1)" "validated prognostic unfavorable (6.06e-5)" "validated prognostic unfavorable (2.29e-7)" "potential prognostic unfavorable (2.19e-4)" "unprognostic (2.41e-1)" "unprognostic (5.05e-3)" "unprognostic (1.20e-1)" "unprognostic (1.10e-1)" "unprognostic (3.33e-1)" "unprognostic (1.98e-3)" "unprognostic (1.09e-2)" "unprognostic (3.44e-2)" "unprognostic (1.62e-1)" "unprognostic (1.35e-1)" "unprognostic (2.80e-3)" "unprognostic (2.88e-1)" "unprognostic (1.84e-1)" "unprognostic (3.30e-1)" "unprognostic (2.09e-1)" SNRPN "HCERN3, PWCR, RT-LI, SM-D, SMN, SNRNP-N, SNURF-SNRPN" ENSG00000128739 "Small nuclear ribonucleoprotein polypeptide N" P63162 15 24823637-24978723 "Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 344.7;Epididymal principal cells: 605.5;Other brain neurons: 328.5;Platelets: 320.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "testis cancer: 466.6" "Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Prostate - Prostate glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003482, HPA067842" Approved Approved Nucleoplasm NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 35: Non-specific - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 109: Neurons - Neuronal signaling" 78 Nucleoplasm "HPA003482: , HPA067842: " "unprognostic (8.49e-2)" "unprognostic (1.92e-1)" "unprognostic (1.48e-2)" "unprognostic (6.23e-2)" "unprognostic (1.45e-1)" "unprognostic (1.02e-1)" "unprognostic (1.90e-1)" "unprognostic (7.73e-2)" "unprognostic (2.71e-2)" "unprognostic (2.27e-1)" "potential prognostic favorable (3.87e-8)" "unprognostic (2.94e-3)" "potential prognostic favorable (3.41e-4)" "unprognostic (9.83e-2)" "unprognostic (3.04e-2)" "unprognostic (1.61e-2)" "unprognostic (1.73e-1)" "unprognostic (1.16e-1)" "unprognostic (9.09e-2)" "unprognostic (1.69e-1)" "unprognostic (6.72e-2)" "unprognostic (6.54e-3)" "unprognostic (1.45e-2)" "unprognostic (1.68e-1)" "unprognostic (1.49e-1)" "unprognostic (7.32e-2)" "unprognostic (2.12e-1)" "unprognostic (2.13e-2)" "unprognostic (2.43e-1)" "unprognostic (5.17e-2)" "unprognostic (6.80e-3)" SNTA1 "LQT12, SNT1, TACIP1" ENSG00000101400 "Syntrophin alpha 1" Q13424 20 33407957-33443763 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Disease variant, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 193.1;heart muscle: 197.4;skeletal muscle: 288.4;tongue: 306.2" "Cell type enhanced" "Detected in many" "Astrocytes: 165.9;Bergmann glia: 90.5;Cardiomyocytes: 64.8;Choroid plexus epithelial cells: 75.8;Müller glia: 66.1;Myonuclei: 204.2;Rod photoreceptor cells: 74.6;Thymic myoid cells: 59.8;Vascular smooth muscle cells: 72.8" "Cell type enhanced" "Detected in all" "astrocyte: 185.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 10.4" "Group enriched" "Detected in many" 4 "B-cells: 5.7;dendritic cells: 10.4" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037059, HPA067154" Approved NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 52: Non-specific - Cellular respiration" "Cluster 19: Astrocytes - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 20 "CAB037059: , HPA067154: " "unprognostic (9.71e-2)" "unprognostic (1.50e-1)" "unprognostic (6.58e-2)" "unprognostic (8.89e-2)" "unprognostic (4.15e-2)" "unprognostic (1.71e-1)" "unprognostic (1.51e-1)" "unprognostic (8.11e-3)" "unprognostic (6.11e-2)" "unprognostic (1.73e-2)" "unprognostic (2.49e-3)" "unprognostic (1.03e-1)" "unprognostic (7.35e-2)" "unprognostic (1.90e-2)" "potential prognostic unfavorable (1.47e-5)" "unprognostic (1.58e-1)" "unprognostic (1.60e-1)" "unprognostic (1.33e-1)" "unprognostic (3.09e-1)" "unprognostic (1.79e-1)" "unprognostic (2.36e-2)" "unprognostic (4.91e-3)" "unprognostic (2.53e-1)" "unprognostic (2.16e-1)" "unprognostic (1.70e-1)" "unprognostic (5.83e-2)" "unprognostic (6.64e-2)" "unprognostic (4.80e-2)" "unprognostic (1.74e-2)" "unprognostic (4.54e-3)" "potential prognostic unfavorable (6.13e-4)" SNTB1 "59-DAP, A1B, BSYN2, SNT2, SNT2B1, TIP-43" ENSG00000172164 "Syntrophin beta 1" Q13884 8 120535745-120813273 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 83.5" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 1124.2;Choroid plexus epithelial cells: 1499.8;Mucous neck cells: 469.6;Renal collecting duct intercalated cells: 1008.9;Salivary ionocytes: 918.1" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 1039.1;pericyte: 772.3" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 99.6" "Region enhanced" "Detected in all" "choroid plexus: 87.1" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Heart muscle - Fibroblasts, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA024659 Uncertain NA NA 5100 "Cluster 41: Basophils - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 3: Choroid plexus - Cilium" "Cluster 32: Non-specific - Cell proliferation" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 18 "HPA024659: " "unprognostic (1.31e-2)" "unprognostic (1.79e-1)" "unprognostic (2.19e-1)" "unprognostic (6.16e-2)" "unprognostic (1.49e-2)" "unprognostic (3.12e-2)" "unprognostic (8.75e-2)" "unprognostic (1.21e-2)" "unprognostic (1.33e-1)" "unprognostic (7.36e-3)" "unprognostic (4.01e-2)" "potential prognostic favorable (2.43e-4)" "potential prognostic unfavorable (2.38e-4)" "unprognostic (1.75e-1)" "unprognostic (3.93e-2)" "potential prognostic favorable (2.35e-4)" "unprognostic (5.14e-2)" "unprognostic (8.37e-2)" "unprognostic (4.25e-1)" "unprognostic (1.97e-1)" "unprognostic (1.04e-1)" "unprognostic (5.14e-2)" "unprognostic (1.53e-1)" "unprognostic (3.49e-1)" "unprognostic (1.38e-1)" "unprognostic (1.08e-1)" "unprognostic (2.12e-1)" "unprognostic (3.17e-2)" "unprognostic (9.45e-2)" "unprognostic (3.29e-2)" "unprognostic (1.25e-1)" SNTB2 "D16S2531E, EST25263, SNT2B2, SNT3, SNTL" ENSG00000168807 "Syntrophin beta 2" Q13425 16 69187147-69309052 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 208.0;Müller glia: 271.6;Rod photoreceptor cells: 177.2;Smooth muscle cells: 161.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001394 Approved "Nucleoplasm,Golgi apparatus,Plasma membrane,Primary cilium transition zone,Centriolar satellite,Basal body" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 47: Testis - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 28 "Golgi apparatus, Plasma membrane, Centriolar satellite, Basal body" "Nucleoplasm, Primary cilium transition zone" "HPA001394: " "unprognostic (2.87e-2)" "unprognostic (4.05e-1)" "unprognostic (1.22e-1)" "unprognostic (1.48e-1)" "unprognostic (2.81e-1)" "potential prognostic unfavorable (2.33e-5)" "unprognostic (4.12e-1)" "unprognostic (1.08e-1)" "unprognostic (9.29e-2)" "unprognostic (1.14e-1)" "unprognostic (1.26e-3)" "unprognostic (1.76e-2)" "unprognostic (1.25e-1)" "unprognostic (9.13e-3)" "unprognostic (2.39e-1)" "unprognostic (5.38e-2)" "unprognostic (1.04e-1)" "unprognostic (2.79e-1)" "unprognostic (2.22e-2)" "unprognostic (1.49e-2)" "unprognostic (6.49e-3)" "unprognostic (3.10e-2)" "unprognostic (1.74e-2)" "unprognostic (6.28e-2)" "unprognostic (5.52e-2)" "unprognostic (1.38e-1)" "unprognostic (4.72e-2)" "unprognostic (7.70e-2)" "unprognostic (3.09e-1)" "unprognostic (2.10e-1)" "unprognostic (8.50e-2)" SNTG1 "G1SYN, SYN4" ENSG00000147481 "Syntrophin gamma 1" Q9NSN8 8 49909789-50796692 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.7;lymphoid tissue: 2.6" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 553.1;Brain excitatory neurons: 1279.3;Brain inhibitory neurons: 1848.0;Corticotrophs: 452.2;Oligodendrocyte progenitor cells: 2990.8;Other brain neurons: 1305.6;Pancreatic islet cells: 534.2;Retinal amacrine cells: 1410.5;Retinal bipolar cells: 437.2;Retinal ganglion cells: 436.5;Somatotrophs: 864.8;Thyrotrophs: 982.1" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in single" 12 "Glioblastoma Multiforme (TCGA): 9.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "thyroid cancer: 2.1" "Adrenal gland - Adrenal medulla cells, Pancreas - Alpha cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072282 Enhanced NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" 9 "HPA072282: " "unprognostic (5.68e-2)" "unprognostic (8.66e-2)" "unprognostic (5.53e-2)" "unprognostic (1.28e-1)" SNTG2 "G2SYN, SYN5" ENSG00000172554 "Syntrophin gamma 2" Q9NY99 2 950849-1367613 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Adipocytes: 156.8;Choroid plexus epithelial cells: 323.0;Corticotrophs: 614.1;Gonadotrophs: 267.0;Lymphatic endothelial cells: 386.9;Other brain neurons: 180.0;Retinal ganglion cells: 204.7;Retinal horizontal cells: 1238.1;Somatotrophs: 286.5;Vascular endothelial cells: 326.0" "Cell type enhanced" "Detected in all" "hippocampal CA4: 303.9;lower rhombic lip: 283.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "thyroid cancer: 1.2" "Colon - Endothelial cells, Pituitary gland - Corticotropes, Skeletal muscle - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "HPA065258, HPA077904" Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 64: Non-specific - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 10 "Plasma membrane" Nucleoplasm "HPA065258: , HPA077904: " "unprognostic (7.77e-2)" SNTN "FLJ44379, S100AL" ENSG00000188817 "Sentan, cilia apical structure protein" A6NMZ2 3 63652675-63679020 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "fallopian tube: 162.9" "Group enriched" "Detected in some" 67 "Endometrial ciliated cells: 547.2;Epididymal efferent duct ciliated cells: 646.8;Fallopian tube ciliated cells: 1140.3;Respiratory ciliated cells: 991.0" "Cell type enriched" "Detected in many" 8 "ependymal cell: 16.8" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 21.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.0" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA043322, HPA058399" Enhanced NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 48: Non-specific - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 107: Ciliated cells - Cilia assembly & function" "HPA043322: , HPA058399: " "unprognostic (6.69e-2)" "unprognostic (1.12e-3)" "unprognostic (3.03e-1)" "unprognostic (1.83e-3)" "unprognostic (2.59e-2)" "unprognostic (1.67e-3)" "unprognostic (1.07e-1)" "unprognostic (3.56e-3)" "unprognostic (5.42e-2)" "unprognostic (2.03e-1)" "unprognostic (1.31e-1)" "unprognostic (2.02e-1)" "unprognostic (2.15e-1)" "unprognostic (9.85e-2)" "unprognostic (2.82e-1)" "unprognostic (6.03e-2)" "unprognostic (4.29e-1)" "unprognostic (6.56e-2)" "unprognostic (3.83e-2)" SNU13 "15.5K, FA-1, NHP2L1, SNRNP15-5, SPAG12, SSFA1" ENSG00000100138 "Small nuclear ribonucleoprotein 13" P55769 22 41673933-41690504 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 1156.5;Late primary spermatocytes: 1304.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA029199 Uncertain NA NA 61000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 1: Neurons - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 17: Non-specific - RNA processing" 59 "HPA029199: " "unprognostic (2.11e-1)" "unprognostic (2.00e-1)" "unprognostic (6.36e-2)" "unprognostic (4.02e-2)" "unprognostic (1.00e-1)" "unprognostic (9.23e-2)" "unprognostic (9.57e-2)" "unprognostic (2.91e-3)" "unprognostic (1.65e-3)" "unprognostic (9.55e-2)" "unprognostic (4.51e-2)" "unprognostic (7.79e-3)" "potential prognostic unfavorable (2.35e-5)" "unprognostic (2.12e-2)" "unprognostic (5.54e-2)" "unprognostic (2.81e-2)" "unprognostic (5.42e-2)" "unprognostic (1.05e-1)" "unprognostic (2.44e-1)" "unprognostic (2.70e-1)" "unprognostic (1.34e-1)" "unprognostic (1.75e-1)" "unprognostic (6.15e-2)" "unprognostic (9.40e-2)" "unprognostic (3.59e-3)" "unprognostic (1.93e-1)" "unprognostic (1.11e-1)" "unprognostic (2.03e-1)" "unprognostic (1.91e-2)" SNUPN "RNUT1, SNURPORTIN-1, Snurportin1" ENSG00000169371 "Snurportin 1" O95149 15 75598083-75626469 "Essential proteins, Predicted intracellular proteins" Transport RNA-binding "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 57.1;Late primary spermatocytes: 90.1;Late spermatids: 43.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005004, HPA069478" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 14: Neurons - Synaptic function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 18 "Nucleoplasm, Plasma membrane, Cytosol" "CAB005004: , HPA069478: " "unprognostic (2.27e-1)" "unprognostic (1.98e-1)" "unprognostic (6.01e-2)" "unprognostic (2.08e-1)" "unprognostic (2.75e-1)" "unprognostic (1.18e-1)" "unprognostic (6.49e-2)" "unprognostic (1.35e-1)" "unprognostic (3.82e-1)" "unprognostic (2.87e-2)" "unprognostic (1.71e-2)" "unprognostic (1.45e-1)" "unprognostic (1.90e-1)" "unprognostic (2.95e-2)" "potential prognostic unfavorable (6.32e-7)" "unprognostic (2.11e-2)" "unprognostic (1.96e-1)" "unprognostic (5.14e-2)" "unprognostic (1.93e-1)" "unprognostic (1.93e-1)" "unprognostic (1.04e-1)" "unprognostic (6.83e-3)" "unprognostic (1.77e-2)" "unprognostic (1.98e-1)" "unprognostic (7.14e-2)" "unprognostic (6.78e-2)" "unprognostic (7.47e-2)" "unprognostic (1.29e-1)" "unprognostic (7.60e-2)" "unprognostic (9.32e-2)" "unprognostic (1.54e-1)" SNURF ENSG00000273173 "SNRPN upstream open reading frame" Q9Y675 15 24954987-24977850 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 90.4;skeletal muscle: 58.2" "Cell type enriched" "Detected in some" 5 "Epididymal principal cells: 31.4" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Region enriched" "Detected in some" 6 "midbrain: 15.1" "Low region specificity" "Detected in all" HPA065733 Supported "Nuclear speckles" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 27: Cerebellum - Synaptic function" "Cluster 2: Neurons - Nucleosome" "Cluster 34: Testis cancer - Unknown function" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" "Nuclear speckles" "HPA065733: " "unprognostic (4.65e-2)" "unprognostic (6.61e-2)" "unprognostic (2.54e-2)" "unprognostic (4.07e-2)" "unprognostic (1.04e-2)" "unprognostic (7.89e-2)" "unprognostic (8.96e-2)" "unprognostic (3.04e-2)" "unprognostic (9.59e-2)" "unprognostic (9.72e-2)" "potential prognostic favorable (2.17e-5)" "unprognostic (9.59e-2)" "unprognostic (6.81e-2)" "unprognostic (1.35e-1)" "unprognostic (1.93e-2)" "unprognostic (6.89e-2)" "unprognostic (2.85e-2)" "unprognostic (3.81e-1)" "unprognostic (1.98e-1)" "unprognostic (1.88e-1)" "unprognostic (2.54e-1)" "unprognostic (1.71e-1)" "unprognostic (7.36e-2)" "unprognostic (5.61e-2)" "unprognostic (4.88e-1)" "unprognostic (1.09e-1)" "unprognostic (1.43e-1)" "unprognostic (1.54e-1)" "unprognostic (7.74e-2)" SNW1 "Bx42, FUN20, NCoA-62, Prp45, PRPF45, SKIIP, SKIP, SKIP1" ENSG00000100603 "SNW domain containing 1" Q13573 14 77717599-77761207 "Essential proteins, Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 305.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002457, CAB009931, HPA017370" Supported Enhanced Nucleoplasm,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 17: Non-specific - RNA processing" 310 Nucleoplasm Cytosol "CAB009931: , HPA002457: , HPA017370: " "unprognostic (6.32e-2)" "unprognostic (1.12e-1)" "unprognostic (1.35e-2)" "unprognostic (4.15e-2)" "unprognostic (1.99e-1)" "unprognostic (8.36e-3)" "unprognostic (9.43e-2)" "unprognostic (1.40e-1)" "unprognostic (2.67e-2)" "potential prognostic unfavorable (4.49e-4)" "potential prognostic favorable (1.62e-4)" "unprognostic (2.91e-2)" "unprognostic (2.02e-1)" "potential prognostic unfavorable (6.03e-5)" "unprognostic (8.65e-3)" "potential prognostic unfavorable (3.66e-4)" "unprognostic (6.81e-2)" "unprognostic (1.15e-2)" "unprognostic (2.01e-1)" "unprognostic (3.19e-1)" "unprognostic (3.74e-2)" "unprognostic (1.27e-1)" "unprognostic (4.24e-3)" "unprognostic (2.58e-1)" "unprognostic (1.87e-1)" "unprognostic (1.10e-1)" "unprognostic (5.28e-2)" "unprognostic (1.40e-1)" "unprognostic (1.39e-1)" "unprognostic (7.14e-2)" "unprognostic (4.70e-2)" SNX1 "HsT17379, MGC8664, SNX1A, Vps5" ENSG00000028528 "Sorting nexin 1" Q13596 15 64094123-64146090 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Myonuclei: 567.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Lung - Alveolar cells type 1, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047373, HPA052761" Approved Enhanced Endosomes,Lysosomes NA NA 9500 "Cluster 42: Non-specific - Vesicular transport" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 58: Non-specific - Nuclear processes" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 65 "Endosomes, Lysosomes" "HPA047373: , HPA052761: " "unprognostic (4.15e-2)" "unprognostic (5.99e-2)" "unprognostic (1.17e-1)" "unprognostic (1.07e-1)" "unprognostic (5.97e-2)" "unprognostic (1.98e-2)" "unprognostic (8.34e-2)" "unprognostic (2.21e-2)" "unprognostic (7.96e-2)" "unprognostic (6.33e-3)" "validated prognostic favorable (2.21e-7)" "validated prognostic favorable (3.49e-6)" "unprognostic (9.61e-2)" "unprognostic (1.39e-1)" "unprognostic (1.70e-1)" "unprognostic (1.06e-1)" "unprognostic (2.08e-2)" "unprognostic (4.07e-2)" "unprognostic (1.85e-1)" "unprognostic (1.31e-1)" "unprognostic (4.16e-2)" "unprognostic (6.19e-2)" "unprognostic (7.01e-3)" "unprognostic (1.22e-1)" "unprognostic (1.10e-1)" "unprognostic (2.30e-1)" "unprognostic (5.99e-2)" "unprognostic (1.08e-1)" "unprognostic (1.83e-1)" "unprognostic (4.27e-2)" "unprognostic (2.50e-2)" SNX10 ENSG00000086300 "Sorting nexin 10" Q9Y5X0 7 26291862-26374383 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Transport" "Disease variant, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 43.2;liver: 41.1" "Cell type enhanced" "Detected in many" "cDC: 168.5;Distal convoluted tubule cells: 363.1;Extravillous trophoblasts: 176.3;Kupffer cells: 413.0;Macrophages: 180.1;Monocyte progenitors: 186.3;monocytes: 253.0;Müller glia: 266.8;Neutrophil progenitors: 286.0;Neutrophils: 1029.3;Renal connecting tubule cells: 163.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 181.1" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "skin cancer: 81.2" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Macrophages, Breast - Adipocytes (Breast), Minor Salivary Gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015605, HPA064782" Approved Supported "Nucleoplasm,Nucleoli,Microtubules,Primary cilium,Cytosol" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 1: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 24: Neutrophils - Innate immunity signal integration" 6 "Nucleoplasm, Microtubules" "Nucleoli, Primary cilium, Cytosol" "HPA015605: , HPA064782: " "unprognostic (2.15e-1)" "unprognostic (1.84e-1)" "unprognostic (1.92e-1)" "unprognostic (1.30e-2)" "unprognostic (1.24e-1)" "unprognostic (2.46e-1)" "potential prognostic unfavorable (3.69e-4)" "unprognostic (2.49e-3)" "unprognostic (2.50e-2)" "unprognostic (2.24e-1)" "unprognostic (4.70e-2)" "unprognostic (2.18e-3)" "unprognostic (6.68e-2)" "unprognostic (9.83e-2)" "unprognostic (1.69e-1)" "unprognostic (3.87e-3)" "unprognostic (7.20e-2)" "unprognostic (6.01e-2)" "unprognostic (3.07e-1)" "unprognostic (1.02e-1)" "unprognostic (8.60e-3)" "unprognostic (1.97e-1)" "potential prognostic unfavorable (1.76e-4)" "unprognostic (1.62e-1)" "unprognostic (9.79e-3)" "unprognostic (2.91e-3)" "unprognostic (3.38e-1)" "unprognostic (6.47e-3)" "unprognostic (3.05e-1)" "unprognostic (1.06e-1)" "unprognostic (1.40e-1)" SNX11 ENSG00000002919 "Sorting nexin 11" Q9Y5W9 17 48103357-48123601 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 50.9;Kupffer cells: 42.0;Neutrophils: 44.1;Oocytes: 64.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044787, HPA054660" Approved Approved "Endoplasmic reticulum,Vesicles" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 97: Non-specific - Cellular respiration" 10 "Endoplasmic reticulum" Vesicles "HPA044787: , HPA054660: " "unprognostic (5.95e-2)" "unprognostic (1.62e-2)" "unprognostic (2.35e-1)" "unprognostic (9.02e-3)" "unprognostic (3.98e-2)" "unprognostic (1.04e-2)" "unprognostic (6.75e-2)" "unprognostic (8.98e-3)" "unprognostic (1.11e-1)" "unprognostic (7.79e-2)" "potential prognostic favorable (5.68e-5)" "unprognostic (8.22e-2)" "unprognostic (1.18e-3)" "potential prognostic unfavorable (1.53e-4)" "unprognostic (2.20e-2)" "unprognostic (2.43e-1)" "unprognostic (1.93e-1)" "unprognostic (5.98e-2)" "unprognostic (2.13e-1)" "unprognostic (1.23e-1)" "unprognostic (4.53e-2)" "unprognostic (8.39e-2)" "potential prognostic unfavorable (6.52e-4)" "unprognostic (3.21e-1)" "unprognostic (1.46e-2)" "unprognostic (5.90e-2)" "unprognostic (6.75e-2)" "unprognostic (3.07e-1)" "unprognostic (2.10e-1)" "unprognostic (1.24e-1)" "unprognostic (2.07e-1)" SNX12 ENSG00000147164 "Sorting nexin 12" Q9UMY4 X 71056332-71073426 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 69.0;Esophageal suprabasal cells: 65.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB070423 Approved NA NA 170000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 45: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 14 "CAB070423: " "unprognostic (1.56e-1)" "unprognostic (9.27e-3)" "unprognostic (3.09e-1)" "unprognostic (1.64e-1)" "unprognostic (2.13e-1)" "unprognostic (5.84e-2)" "unprognostic (1.16e-1)" "potential prognostic favorable (6.84e-4)" "unprognostic (1.38e-2)" "unprognostic (2.91e-2)" "potential prognostic favorable (4.25e-6)" "unprognostic (4.32e-2)" "unprognostic (2.31e-1)" "unprognostic (5.66e-2)" "unprognostic (1.69e-2)" "unprognostic (1.31e-2)" "potential prognostic unfavorable (6.56e-4)" "unprognostic (2.37e-1)" "unprognostic (1.28e-1)" "unprognostic (5.75e-2)" "unprognostic (8.85e-2)" "unprognostic (1.27e-2)" "unprognostic (4.67e-2)" "unprognostic (4.47e-1)" "unprognostic (1.41e-1)" "unprognostic (5.89e-2)" "unprognostic (1.40e-1)" "unprognostic (1.39e-1)" "unprognostic (6.77e-2)" "unprognostic (3.72e-1)" "unprognostic (1.62e-2)" SNX13 "KIAA0713, RGS-PX1" ENSG00000071189 "Sorting nexin 13" Q9Y5W8 7 17790761-17940501 "Predicted membrane proteins" "Protein transport, Transport" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 475.5;Late spermatids: 407.4;Neutrophils: 355.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 67: Non-specific - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" 1 "unprognostic (1.51e-1)" "unprognostic (1.19e-1)" "unprognostic (5.65e-2)" "unprognostic (2.03e-2)" "unprognostic (6.79e-2)" "unprognostic (1.52e-1)" "unprognostic (3.72e-2)" "unprognostic (5.44e-2)" "unprognostic (1.70e-1)" "unprognostic (1.97e-1)" "potential prognostic favorable (5.43e-7)" "unprognostic (2.09e-3)" "unprognostic (1.09e-2)" "unprognostic (6.01e-3)" "unprognostic (4.42e-2)" "unprognostic (1.41e-1)" "unprognostic (2.09e-1)" "unprognostic (7.38e-2)" "unprognostic (1.55e-1)" "unprognostic (1.05e-1)" "potential prognostic unfavorable (3.12e-4)" "unprognostic (7.43e-2)" "unprognostic (2.76e-3)" "unprognostic (2.57e-1)" "unprognostic (3.48e-2)" "unprognostic (9.41e-2)" "unprognostic (1.37e-1)" "unprognostic (7.73e-2)" "unprognostic (2.96e-1)" "unprognostic (5.91e-2)" "unprognostic (1.93e-1)" SNX14 RGS-PX2 ENSG00000135317 "Sorting nexin 14" Q9Y5W7 6 85504776-85594156 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Disease variant, Intellectual disability, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 135.5;Bergmann glia: 135.5;Brain excitatory neurons: 155.7;Brain inhibitory neurons: 151.9;Choroid plexus epithelial cells: 199.6;Distal convoluted tubule cells: 123.9;Ependymal cells: 157.8;Loop of henle epithelial cells: 95.8;Microglia: 156.7;Oligodendrocyte progenitor cells: 146.9;Oligodendrocytes: 126.1;Other brain neurons: 150.8;Papillary tip epithelial cells: 78.1;Podocytes: 108.7;Proximal tubule cells: 111.9;Renal collecting duct intercalated cells: 111.2;Renal collecting duct principal cells: 87.6;Renal connecting tubule cells: 105.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 19.2" "Group enriched" "Detected in all" 4 "granulocytes: 19.2;monocytes: 12.0" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017639 Approved Supported Vesicles,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 67: Testis - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 102: Non-specific - Mixed function" 1 "Vesicles, Cytosol" "HPA017639: " "unprognostic (1.09e-1)" "unprognostic (2.99e-2)" "unprognostic (1.45e-3)" "unprognostic (5.51e-3)" "unprognostic (3.32e-2)" "unprognostic (1.03e-1)" "unprognostic (2.55e-1)" "unprognostic (6.86e-2)" "unprognostic (1.32e-3)" "unprognostic (5.55e-2)" "unprognostic (1.23e-1)" "unprognostic (2.71e-2)" "unprognostic (2.85e-2)" "unprognostic (4.64e-3)" "unprognostic (5.12e-2)" "unprognostic (4.44e-2)" "unprognostic (1.05e-1)" "unprognostic (1.25e-2)" "unprognostic (5.35e-2)" "unprognostic (1.32e-3)" "unprognostic (6.23e-2)" "unprognostic (5.49e-2)" "unprognostic (5.76e-3)" "unprognostic (1.55e-1)" "unprognostic (1.19e-2)" "unprognostic (7.90e-2)" "unprognostic (1.14e-1)" "unprognostic (2.49e-2)" "unprognostic (1.46e-1)" "unprognostic (2.41e-3)" "unprognostic (1.77e-1)" SNX15 ENSG00000110025 "Sorting nexin 15" Q9NRS6 11 65027439-65040572 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 8.3;Bergmann glia: 17.6;Brain excitatory neurons: 10.7;Brain inhibitory neurons: 9.3;Choroid plexus epithelial cells: 5.3;Colonocytes: 5.9;Enteric stem cells: 6.3;Enteric transient amplifying cells: 6.4;Enterocytes: 5.3;Epididymal clear cells: 6.1;Microglia: 5.8;Oligodendrocyte progenitor cells: 9.0;Oligodendrocytes: 12.9;Other brain neurons: 11.0;Paneth cells: 7.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038955 Approved Approved "Nucleoli,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" 8 "Nucleoli, Cytosol" "Vesicles, Plasma membrane" "HPA038955: " "unprognostic (1.31e-1)" "unprognostic (2.10e-2)" "unprognostic (7.85e-3)" "unprognostic (1.78e-1)" "unprognostic (2.28e-1)" "unprognostic (2.83e-2)" "unprognostic (2.06e-2)" "unprognostic (4.83e-2)" "unprognostic (1.75e-1)" "unprognostic (5.54e-3)" "potential prognostic favorable (7.67e-8)" "unprognostic (2.56e-2)" "unprognostic (2.03e-1)" "potential prognostic unfavorable (7.07e-7)" "unprognostic (8.47e-3)" "potential prognostic unfavorable (2.33e-4)" "unprognostic (2.38e-2)" "unprognostic (1.60e-2)" "unprognostic (1.21e-1)" "unprognostic (1.82e-1)" "unprognostic (8.82e-2)" "unprognostic (1.12e-1)" "unprognostic (3.47e-1)" "unprognostic (9.46e-2)" "unprognostic (2.24e-2)" "unprognostic (1.60e-1)" "unprognostic (2.14e-1)" "unprognostic (9.31e-2)" "unprognostic (1.38e-1)" "unprognostic (3.20e-1)" "unprognostic (3.31e-2)" SNX16 ENSG00000104497 "Sorting nexin 16" P57768 8 81799581-81842866 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 87.0;Esophageal apical cells: 248.0;Late primary spermatocytes: 89.5;Late spermatids: 219.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024730, HPA024731, HPA024817" Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 84: Apical squamous epithelium - Cornification" "Vesicles, Plasma membrane" "HPA024730: , HPA024731: , HPA024817: " "unprognostic (4.19e-2)" "unprognostic (3.91e-2)" "unprognostic (8.53e-2)" "unprognostic (7.35e-3)" "unprognostic (2.27e-1)" "unprognostic (1.57e-2)" "unprognostic (3.23e-2)" "unprognostic (9.62e-2)" "unprognostic (7.45e-2)" "unprognostic (4.06e-2)" "potential prognostic favorable (3.56e-5)" "unprognostic (6.96e-3)" "unprognostic (1.51e-3)" "unprognostic (3.88e-3)" "unprognostic (4.42e-2)" "unprognostic (1.06e-1)" "unprognostic (1.65e-1)" "unprognostic (2.74e-1)" "unprognostic (1.18e-1)" "unprognostic (4.06e-2)" "potential prognostic unfavorable (4.70e-4)" "unprognostic (2.79e-2)" "unprognostic (1.28e-2)" "unprognostic (1.54e-1)" "unprognostic (5.08e-1)" "unprognostic (3.09e-2)" "unprognostic (8.92e-2)" "unprognostic (1.29e-2)" "unprognostic (3.08e-1)" "unprognostic (1.14e-1)" "unprognostic (5.01e-2)" SNX17 KIAA0064 ENSG00000115234 "Sorting nexin 17" Q15036 2 27370496-27377535 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 204.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043867 Supported Enhanced Vesicles,Cytosol No No "Cluster 29: Non-specific - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 27: Non-specific - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 17 Vesicles Cytosol "HPA043867: " "unprognostic (7.87e-2)" "unprognostic (1.14e-2)" "unprognostic (4.19e-2)" "unprognostic (2.38e-2)" "unprognostic (2.37e-2)" "unprognostic (2.01e-1)" "unprognostic (1.39e-1)" "unprognostic (4.09e-1)" "unprognostic (2.60e-1)" "unprognostic (8.33e-3)" "potential prognostic favorable (8.93e-7)" "unprognostic (6.19e-2)" "unprognostic (9.56e-2)" "unprognostic (1.06e-2)" "potential prognostic unfavorable (6.58e-5)" "unprognostic (1.53e-1)" "unprognostic (3.69e-3)" "unprognostic (6.59e-2)" "unprognostic (1.33e-1)" "unprognostic (3.65e-1)" "unprognostic (6.97e-2)" "unprognostic (2.94e-1)" "unprognostic (1.82e-1)" "unprognostic (1.25e-1)" "unprognostic (7.73e-2)" "unprognostic (1.45e-1)" "unprognostic (1.44e-2)" "unprognostic (1.38e-1)" "unprognostic (2.73e-1)" "unprognostic (2.57e-2)" "unprognostic (1.32e-1)" SNX18 "SH3PX2, SH3PXD3B, SNAG1" ENSG00000178996 "Sorting nexin 18" Q96RF0 5 54517759-54546586 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Endocytosis, Mitosis, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 64.2" "Cell type enhanced" "Detected in many" "Kupffer cells: 155.8;Microglia: 124.7;monocytes: 95.1;Neutrophils: 202.5" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 152.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Smooth muscle cells, Spleen - Macrophages, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037800 Approved Approved Cytosol NA NA 6200 "Cluster 2: Dendritic cells - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 19: Astrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 20 Cytosol "HPA037800: " "unprognostic (7.40e-2)" "unprognostic (1.53e-2)" "unprognostic (4.28e-3)" "unprognostic (2.92e-1)" "unprognostic (2.51e-1)" "unprognostic (3.06e-1)" "unprognostic (2.15e-1)" "unprognostic (2.32e-1)" "unprognostic (1.89e-1)" "unprognostic (1.70e-3)" "potential prognostic favorable (8.64e-8)" "unprognostic (2.02e-2)" "unprognostic (2.46e-1)" "unprognostic (4.84e-2)" "unprognostic (8.54e-3)" "unprognostic (1.02e-1)" "unprognostic (8.65e-3)" "unprognostic (1.27e-1)" "unprognostic (1.04e-1)" "unprognostic (7.67e-2)" "potential prognostic unfavorable (2.63e-4)" "unprognostic (3.42e-3)" "unprognostic (1.94e-1)" "unprognostic (9.18e-3)" "unprognostic (2.26e-1)" "unprognostic (1.52e-1)" "unprognostic (7.58e-2)" "unprognostic (1.37e-2)" "unprognostic (1.82e-1)" "unprognostic (1.21e-1)" "unprognostic (1.30e-1)" SNX19 "CHET8, KIAA0254" ENSG00000120451 "Sorting nexin 19" Q92543 11 130866250-130916479 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013447 Uncertain Approved Mitochondria NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 27: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 9 Mitochondria "HPA013447: " "unprognostic (2.11e-2)" "unprognostic (1.40e-2)" "unprognostic (8.02e-2)" "unprognostic (2.99e-2)" "unprognostic (2.78e-1)" "unprognostic (8.63e-3)" "unprognostic (1.79e-1)" "unprognostic (5.84e-2)" "unprognostic (2.33e-1)" "unprognostic (4.23e-2)" "potential prognostic favorable (4.18e-7)" "unprognostic (7.56e-2)" "unprognostic (3.62e-2)" "unprognostic (2.15e-1)" "unprognostic (2.83e-2)" "unprognostic (2.55e-1)" "unprognostic (3.16e-2)" "unprognostic (9.54e-2)" "unprognostic (9.58e-3)" "unprognostic (3.02e-3)" "unprognostic (1.90e-2)" "unprognostic (5.57e-2)" "unprognostic (1.01e-1)" "unprognostic (1.97e-1)" "unprognostic (4.09e-3)" "unprognostic (1.06e-1)" "unprognostic (1.84e-2)" "unprognostic (3.24e-2)" "unprognostic (4.10e-1)" "unprognostic (3.51e-2)" "unprognostic (2.33e-1)" SNX2 ENSG00000205302 "Sorting nexin 2" O60749 5 122775079-122834543 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "B-cells: 391.0;Extravillous trophoblasts: 430.0;Hofbauer cells: 683.0;Migrating cytotrophoblasts: 379.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "memory B-cell: 291.0;naive B-cell: 290.2" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Fibroblasts, Lung - Macrophages, Spleen - Macrophages, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037400, HPA077664" Approved Enhanced Endosomes,Lysosomes NA NA 180000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 55: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 60 Endosomes Lysosomes "HPA037400: , HPA077664: " "unprognostic (1.27e-1)" "unprognostic (9.68e-3)" "unprognostic (4.77e-2)" "unprognostic (9.50e-2)" "unprognostic (1.36e-1)" "unprognostic (1.98e-1)" "unprognostic (2.60e-1)" "unprognostic (2.96e-1)" "unprognostic (2.39e-1)" "unprognostic (1.19e-1)" "potential prognostic favorable (1.50e-12)" "unprognostic (3.88e-3)" "unprognostic (7.01e-2)" "unprognostic (8.47e-3)" "unprognostic (2.87e-1)" "unprognostic (2.42e-1)" "unprognostic (2.72e-1)" "unprognostic (1.18e-1)" "unprognostic (2.50e-3)" "unprognostic (1.32e-1)" "potential prognostic unfavorable (2.07e-4)" "unprognostic (2.35e-1)" "unprognostic (9.18e-2)" "unprognostic (1.62e-1)" "unprognostic (1.29e-2)" "unprognostic (4.84e-3)" "unprognostic (3.23e-2)" "unprognostic (1.83e-1)" "unprognostic (2.02e-1)" "unprognostic (1.01e-1)" "unprognostic (3.23e-1)" SNX20 "SLIC-1, SLIC1" ENSG00000167208 "Sorting nexin 20" Q7Z614 16 50666300-50681353 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.7;lymphoid tissue: 30.9" "Cell type enhanced" "Detected in some" "B-cells: 13.4;cDC: 34.2;Hematopoietic stem cells: 15.5;Hofbauer cells: 18.2;Innate lymphoid cells: 15.5;Kupffer cells: 13.3;Macrophages: 16.1;Megakaryocytes: 18.5;Monocyte progenitors: 27.2;monocytes: 32.1;Neutrophil progenitors: 31.3;Neutrophils: 65.8;NK-cells: 23.7;pDCs: 28.6;T-cells: 22.1" "Group enriched" "Detected in some" 27 "central nervous system macrophage: 9.3;leukocyte: 26.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 35 "Leukemia: 17.0;lymphoma: 14.3;Myeloma: 5.8" "Adipose visceral - Macrophages, Adrenal gland - Macrophages, Liver - Kupffer cells, Lung - T-cells, Skeletal muscle - Macrophages, Spleen - T-cells, Testis - Macrophages" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA043649 Uncertain Uncertain Nucleoplasm NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 6 Nucleoplasm "HPA043649: " "unprognostic (4.84e-2)" "unprognostic (1.65e-2)" "unprognostic (1.71e-2)" "unprognostic (3.73e-3)" "unprognostic (1.60e-1)" "unprognostic (1.09e-1)" "unprognostic (7.75e-2)" "unprognostic (6.57e-2)" "unprognostic (2.80e-3)" "unprognostic (2.94e-1)" "unprognostic (1.83e-1)" "unprognostic (4.70e-1)" "unprognostic (3.47e-2)" "unprognostic (2.96e-1)" "unprognostic (3.88e-2)" "potential prognostic favorable (1.44e-4)" "unprognostic (6.87e-2)" "unprognostic (2.79e-1)" "unprognostic (1.92e-1)" "unprognostic (1.49e-1)" "unprognostic (1.41e-1)" "unprognostic (3.55e-2)" "unprognostic (8.06e-2)" "unprognostic (3.59e-1)" "unprognostic (1.21e-2)" "unprognostic (3.96e-2)" "unprognostic (2.44e-3)" "unprognostic (1.06e-1)" "unprognostic (4.50e-2)" "unprognostic (1.65e-1)" "unprognostic (1.54e-1)" SNX21 "C20orf161, dJ337O18.4, SNX-L" ENSG00000124104 "Sorting nexin family member 21" Q969T3 20 45833799-45843276 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 66.0;Decidual stromal cells: 83.6;Esophageal apical cells: 121.7;Myonuclei: 69.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 2.8;classical monocyte: 1.6;eosinophil: 4.9;intermediate monocyte: 2.6;non-classical monocyte: 2.0" "Group enriched" "Detected in many" 8 "granulocytes: 4.9;monocytes: 2.6" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046359 Approved Approved "Vesicles,Centriolar satellite" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 72: Neuronal - Signal transduction" "Cluster 108: Fibroblasts - ECM organization" Vesicles "Centriolar satellite" "HPA046359: " "unprognostic (3.80e-1)" "unprognostic (6.03e-2)" "unprognostic (1.89e-2)" "unprognostic (1.23e-1)" "unprognostic (1.79e-1)" "unprognostic (2.07e-2)" "unprognostic (5.48e-2)" "potential prognostic unfavorable (9.34e-4)" "unprognostic (4.81e-1)" "unprognostic (1.31e-1)" "potential prognostic favorable (5.07e-4)" "unprognostic (1.13e-1)" "unprognostic (8.15e-2)" "unprognostic (1.74e-2)" "unprognostic (1.27e-2)" "unprognostic (3.01e-2)" "unprognostic (1.72e-2)" "unprognostic (5.42e-2)" "unprognostic (6.64e-2)" "unprognostic (1.33e-2)" "unprognostic (9.00e-3)" "unprognostic (1.91e-1)" "unprognostic (1.93e-1)" "unprognostic (1.48e-1)" "unprognostic (3.03e-2)" "unprognostic (2.18e-2)" "unprognostic (1.10e-1)" "unprognostic (3.99e-1)" "unprognostic (1.54e-1)" "unprognostic (1.61e-2)" "unprognostic (7.31e-2)" SNX22 FLJ13952 ENSG00000157734 "Sorting nexin 22" Q96L94 15 64151715-64157481 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.5;thyroid gland: 36.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 80.8;B-cells: 33.1;Cardiomyocytes: 51.9;Epicardial cells: 97.8;Erythrocyte progenitors: 30.2;Oligodendrocyte progenitor cells: 138.8;Oligodendrocytes: 42.8;Oocytes: 27.6;Plasma cells: 24.0" "Group enriched" "Detected in many" 4 "committed oligodendrocyte precursor: 109.9;oligodendrocyte precursor cell: 175.2" "Cancer enriched" "Detected in many" 7 "Thyroid Carcinoma (TCGA): 78.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "memory B-cell: 3.3;naive B-cell: 6.1" "Lineage enriched" "Detected in many" 6 "B-cells: 6.1" "Cancer enhanced" "Detected in some" "lymphoma: 7.0" "Pituitary gland - Corticotropes, Spleen - B-cells (Spleen), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038470 Approved Nucleoplasm,Vesicles NA NA "Cluster 18: Non-specific - Translation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 43: Hindbrain - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 2 Vesicles Nucleoplasm "HPA038470: " "potential prognostic favorable (1.47e-4)" "unprognostic (1.71e-1)" "unprognostic (7.86e-2)" "unprognostic (8.69e-3)" "unprognostic (2.48e-3)" "unprognostic (3.61e-2)" "unprognostic (2.61e-1)" "unprognostic (5.71e-2)" "unprognostic (1.65e-3)" "potential prognostic favorable (8.29e-5)" "unprognostic (1.83e-1)" "unprognostic (5.67e-2)" "unprognostic (6.77e-3)" "unprognostic (1.39e-1)" "unprognostic (5.90e-2)" "unprognostic (4.35e-2)" "unprognostic (3.56e-3)" "unprognostic (2.19e-2)" SNX24 SBBI31 ENSG00000064652 "Sorting nexin 24" Q9Y343 5 122843439-123029354 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 720.1;Kupffer cells: 268.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 3.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044566, HPA073934" Approved Approved Vesicles NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 45: Non-specific - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 10 Vesicles "HPA044566: , HPA073934: " "unprognostic (5.34e-2)" "unprognostic (3.00e-1)" "unprognostic (6.75e-2)" "unprognostic (2.08e-1)" "unprognostic (1.32e-2)" "unprognostic (1.00e-1)" "unprognostic (6.15e-2)" "unprognostic (7.75e-2)" "unprognostic (2.25e-1)" "unprognostic (4.30e-2)" "potential prognostic favorable (1.99e-4)" "unprognostic (2.55e-2)" "unprognostic (2.10e-2)" "unprognostic (1.07e-3)" "unprognostic (1.33e-2)" "unprognostic (1.18e-1)" "unprognostic (7.94e-2)" "unprognostic (2.80e-1)" "unprognostic (5.88e-2)" "unprognostic (8.14e-2)" "unprognostic (7.12e-2)" "unprognostic (4.10e-2)" "unprognostic (5.75e-2)" "unprognostic (1.59e-1)" "unprognostic (4.98e-2)" "unprognostic (3.50e-1)" "unprognostic (8.47e-2)" "unprognostic (3.26e-2)" "unprognostic (2.48e-1)" "unprognostic (1.56e-1)" "unprognostic (2.66e-3)" SNX25 SBBI31 ENSG00000109762 "Sorting nexin 25" Q9H3E2 4 185204237-185370185 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 402.6;Alveolar cells type 2: 1114.8;Melanocytes: 360.0;Pituicytes/FSCs: 413.8;Podocytes: 793.1;Transitional alveolar cells: 531.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Thyroid Carcinoma (TCGA): 36.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036928 Supported Vesicles NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 81: Alveolar cells - Lung function" 3 Vesicles "HPA036928: " "unprognostic (4.88e-2)" "unprognostic (7.87e-3)" "unprognostic (1.88e-1)" "unprognostic (1.10e-1)" "unprognostic (2.15e-1)" "unprognostic (6.66e-2)" "unprognostic (2.21e-1)" "unprognostic (8.69e-2)" "unprognostic (1.47e-1)" "unprognostic (2.15e-3)" "validated prognostic favorable (2.61e-4)" "validated prognostic favorable (2.45e-5)" "unprognostic (1.43e-1)" "unprognostic (1.41e-3)" "unprognostic (3.54e-1)" "unprognostic (1.36e-2)" "unprognostic (7.16e-3)" "unprognostic (7.34e-2)" "unprognostic (1.37e-1)" "unprognostic (1.77e-2)" "unprognostic (1.69e-1)" "unprognostic (1.94e-2)" "potential prognostic unfavorable (7.53e-4)" "unprognostic (2.11e-1)" "unprognostic (1.31e-1)" "unprognostic (3.67e-1)" "unprognostic (3.54e-2)" "unprognostic (1.53e-1)" "unprognostic (5.44e-2)" "unprognostic (2.59e-2)" "unprognostic (6.90e-2)" SNX27 "KIAA0488, MGC20471, MY014" ENSG00000143376 "Sorting nexin 27" Q96L92 1 151612006-151699091 "Plasma proteins, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 527.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 21.6;classical monocyte: 35.8;intermediate monocyte: 30.8;myeloid DC: 16.2;neutrophil: 40.5;non-classical monocyte: 35.4" "Group enriched" "Detected in all" 5 "dendritic cells: 16.2;granulocytes: 40.5;monocytes: 35.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028551 Supported Vesicles NA NA 10000 "Cluster 40: Monocytes - Innate immune response" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 57 Vesicles "HPA028551: " "unprognostic (3.37e-2)" "unprognostic (5.20e-2)" "unprognostic (4.15e-2)" "unprognostic (8.17e-2)" "unprognostic (2.04e-1)" "unprognostic (1.35e-1)" "unprognostic (7.54e-2)" "unprognostic (3.51e-2)" "unprognostic (1.96e-1)" "unprognostic (4.11e-3)" "potential prognostic favorable (9.90e-5)" "unprognostic (4.07e-2)" "unprognostic (4.27e-1)" "unprognostic (1.16e-2)" "unprognostic (5.34e-3)" "unprognostic (2.89e-1)" "unprognostic (2.02e-2)" "unprognostic (2.28e-2)" "unprognostic (7.58e-2)" "unprognostic (9.76e-2)" "unprognostic (8.30e-2)" "unprognostic (1.62e-1)" "unprognostic (2.95e-2)" "unprognostic (1.60e-2)" "unprognostic (2.75e-1)" "unprognostic (4.14e-1)" "unprognostic (8.52e-2)" "unprognostic (7.18e-2)" "unprognostic (3.01e-1)" "unprognostic (8.65e-2)" "unprognostic (2.61e-2)" SNX29 "FLJ12363, RUNDC2A" ENSG00000048471 "Sorting nexin 29" Q8TEQ0 16 11976734-12574287 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 2109.4;Distal convoluted tubule cells: 1155.2;Proximal tubule cells: 1412.4;Renal connecting tubule cells: 1053.7;Rod photoreceptor cells: 1227.8;Somatotrophs: 845.5" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 908.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "naive B-cell: 22.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Macrophages, Breast - Fibroblasts, Minor Salivary Gland - Macrophages, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008889, HPA062810" Approved Approved "Nucleoli,Golgi apparatus,Cytosol" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 6: Non-specific - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 88: Proximal tubular cells - Transmembrane transport" 5 "Golgi apparatus" "Nucleoli, Cytosol" "HPA008889: , HPA062810: " "unprognostic (2.90e-2)" "unprognostic (1.90e-1)" "unprognostic (1.69e-2)" "unprognostic (8.12e-2)" "unprognostic (1.33e-1)" "unprognostic (5.24e-3)" "unprognostic (2.47e-1)" "unprognostic (1.08e-1)" "unprognostic (3.81e-2)" "unprognostic (1.24e-1)" "validated prognostic favorable (1.29e-8)" "validated prognostic favorable (1.78e-4)" "unprognostic (1.70e-2)" "potential prognostic unfavorable (3.12e-4)" "unprognostic (6.66e-2)" "unprognostic (2.55e-2)" "unprognostic (2.10e-1)" "unprognostic (9.90e-3)" "unprognostic (1.48e-1)" "unprognostic (1.88e-2)" "potential prognostic unfavorable (7.56e-4)" "unprognostic (1.48e-1)" "unprognostic (6.39e-3)" "unprognostic (4.16e-2)" "unprognostic (5.71e-2)" "unprognostic (1.24e-2)" "unprognostic (8.24e-2)" "unprognostic (1.08e-2)" "unprognostic (3.89e-1)" "unprognostic (7.24e-2)" "unprognostic (5.65e-2)" SNX3 Grd19 ENSG00000112335 "Sorting nexin 3" O60493 6 108211222-108261246 "Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" Microphthalmia "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1674.5;Esophageal suprabasal cells: 942.3;Hofbauer cells: 1602.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 560000 "Cluster 29: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 82: Dendritic cells - Antigen presentation" 47 "unprognostic (1.87e-1)" "potential prognostic unfavorable (5.83e-5)" "unprognostic (1.26e-1)" "unprognostic (2.64e-2)" "unprognostic (3.10e-1)" "unprognostic (1.40e-1)" "unprognostic (1.33e-1)" "unprognostic (1.90e-2)" "unprognostic (1.60e-2)" "potential prognostic unfavorable (3.78e-4)" "unprognostic (1.91e-3)" "unprognostic (2.00e-1)" "unprognostic (9.75e-3)" "potential prognostic unfavorable (3.20e-4)" "unprognostic (1.12e-2)" "unprognostic (3.85e-2)" "unprognostic (3.08e-2)" "unprognostic (3.23e-2)" "unprognostic (3.00e-2)" "unprognostic (1.10e-2)" "unprognostic (3.01e-2)" "unprognostic (3.27e-1)" "unprognostic (1.82e-1)" "unprognostic (6.81e-2)" "unprognostic (8.90e-2)" "unprognostic (2.18e-2)" "unprognostic (4.01e-1)" "unprognostic (2.81e-3)" "unprognostic (1.67e-1)" "unprognostic (6.75e-2)" "unprognostic (9.07e-2)" SNX30 ATG24A ENSG00000148158 "Sorting nexin family member 30" Q5VWJ9 9 112750760-112881671 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 320.6;Oligodendrocytes: 155.4;Proximal tubule cells: 266.6;Somatotrophs: 118.3;Transitional alveolar cells: 173.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Lung - Alveolar cells type 2, Spleen - Macrophages, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019346 Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 81: Alveolar cells - Lung function" 8 "Nucleoplasm, Nucleoli, Cytosol" "HPA019346: " "unprognostic (1.00e-1)" "unprognostic (8.78e-3)" "unprognostic (1.36e-1)" "unprognostic (2.27e-2)" "unprognostic (5.97e-2)" "unprognostic (8.01e-2)" "unprognostic (3.68e-1)" "unprognostic (3.94e-3)" "unprognostic (1.65e-1)" "unprognostic (2.14e-2)" "potential prognostic favorable (1.17e-11)" "unprognostic (1.35e-3)" "unprognostic (6.86e-2)" "unprognostic (6.13e-3)" "unprognostic (2.71e-1)" "potential prognostic favorable (1.65e-4)" "unprognostic (9.07e-2)" "unprognostic (3.33e-1)" "unprognostic (1.05e-1)" "potential prognostic unfavorable (7.45e-4)" "unprognostic (3.46e-1)" "unprognostic (1.36e-1)" "unprognostic (2.80e-1)" "unprognostic (1.95e-1)" "unprognostic (1.33e-2)" "unprognostic (4.57e-1)" "unprognostic (1.16e-1)" "unprognostic (1.83e-2)" "unprognostic (1.93e-1)" "unprognostic (2.20e-1)" "unprognostic (5.09e-2)" SNX31 MGC39715 ENSG00000174226 "Sorting nexin 31" Q8N9S9 8 100572889-100663415 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 6.1;urinary bladder: 15.4" "Cell type enhanced" "Detected in many" "Early spermatids: 132.3;Ependymal cells: 54.0;Esophageal apical cells: 120.7;Papillary tip epithelial cells: 195.3;pDCs: 182.2;Prostatic hillock cells: 161.2;Respiratory basal cells: 229.4;Urothelial cells: 164.7" "Cell type enhanced" "Detected in many" "ependymal cell: 57.2" "Cancer enriched" "Detected in many" 10 "Bladder Urothelial Carcinoma (TCGA): 44.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "Bladder cancer: 5.8" "Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in single" 5 "thalamus: 2.6" "Region enhanced" "Detected in single" "olfactory bulb: 1.7" "HPA024284, HPA053466" Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 20: Non-specific - Transcription regulation" 1 "Nucleoplasm, Golgi apparatus" Cytosol "HPA024284: , HPA053466: " "unprognostic (5.86e-2)" "unprognostic (7.21e-3)" "unprognostic (3.46e-3)" "unprognostic (2.53e-2)" "unprognostic (1.17e-2)" "unprognostic (7.74e-3)" "unprognostic (1.70e-1)" "unprognostic (1.13e-1)" "unprognostic (3.85e-2)" "unprognostic (2.15e-2)" "unprognostic (8.59e-2)" SNX32 "FLJ30934, SNX6B" ENSG00000172803 "Sorting nexin 32" Q86XE0 11 65833834-65856896 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "brain: 26.7" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 82.2;Cardiomyocytes: 108.3;Epicardial cells: 211.5;Mesothelial cells: 69.0;Paneth cells: 69.6;Plasma cells: 73.4;Thymocytes: 84.7" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Glioblastoma Multiforme (TCGA): 3.3;Ovary Serous Cystadenocarcinoma (TCGA): 1.5;Skin Cutaneous Melanoma (TCGA): 2.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 1.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041775 Uncertain Approved "Focal adhesion sites,Cytosol" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 14 Cytosol "Focal adhesion sites" "HPA041775: " "unprognostic (1.62e-1)" "unprognostic (3.68e-2)" "unprognostic (3.17e-2)" "unprognostic (1.68e-3)" "unprognostic (2.19e-1)" "unprognostic (5.52e-2)" "unprognostic (1.44e-1)" "unprognostic (3.25e-2)" SNX33 "MGC32065, SH3PX3, SH3PXD3C, SNX30" ENSG00000173548 "Sorting nexin 33" Q8WV41 15 75647912-75662301 "Predicted intracellular proteins" "Cell cycle, Cell division, Endocytosis, Mitosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Esophageal apical cells: 123.1" "Cell type enhanced" "Detected in many" "fibroblast: 16.1;pericyte: 19.5;vascular associated smooth muscle cell: 24.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040988 Approved NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 84: Apical squamous epithelium - Cornification" 33 "HPA040988: " "unprognostic (8.69e-2)" "unprognostic (5.78e-2)" "unprognostic (4.66e-2)" "unprognostic (2.45e-3)" "unprognostic (8.97e-2)" "unprognostic (1.59e-1)" "unprognostic (1.18e-1)" "unprognostic (9.22e-2)" "unprognostic (9.14e-2)" "unprognostic (1.89e-1)" "potential prognostic favorable (3.95e-5)" "unprognostic (4.14e-2)" "unprognostic (1.76e-1)" "unprognostic (1.30e-1)" "unprognostic (1.13e-2)" "unprognostic (3.45e-2)" "unprognostic (5.20e-2)" "unprognostic (5.34e-2)" "unprognostic (2.73e-1)" "unprognostic (3.09e-3)" "unprognostic (4.40e-2)" "unprognostic (4.21e-3)" "unprognostic (1.43e-1)" "unprognostic (2.62e-2)" "unprognostic (2.59e-2)" "unprognostic (6.86e-3)" "unprognostic (7.19e-2)" "unprognostic (5.83e-2)" "unprognostic (1.99e-1)" "unprognostic (1.04e-1)" "unprognostic (1.16e-1)" SNX4 ATG24B ENSG00000114520 "Sorting nexin 4" O95219 3 125446650-125520202 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005709 Uncertain NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 76: Non-specific - Metabolism" "Cluster 55: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 7: Non-specific - Transcription" 26 "HPA005709: " "unprognostic (1.60e-1)" "unprognostic (1.60e-1)" "unprognostic (5.96e-2)" "unprognostic (2.52e-1)" "unprognostic (6.47e-2)" "unprognostic (1.99e-1)" "unprognostic (8.92e-2)" "unprognostic (7.98e-2)" "unprognostic (7.58e-2)" "unprognostic (9.19e-2)" "potential prognostic favorable (1.90e-8)" "unprognostic (2.65e-1)" "unprognostic (1.08e-1)" "unprognostic (2.94e-3)" "unprognostic (2.80e-2)" "unprognostic (2.87e-1)" "unprognostic (1.59e-1)" "unprognostic (1.66e-1)" "unprognostic (2.45e-1)" "unprognostic (2.37e-2)" "potential prognostic unfavorable (1.28e-4)" "unprognostic (1.81e-1)" "unprognostic (2.07e-1)" "unprognostic (1.12e-1)" "unprognostic (8.70e-2)" "potential prognostic unfavorable (8.10e-4)" "unprognostic (8.83e-2)" "unprognostic (2.92e-2)" "unprognostic (1.75e-1)" "unprognostic (1.53e-3)" "unprognostic (3.32e-2)" SNX5 ENSG00000089006 "Sorting nexin 5" Q9Y5X3 20 17941597-17968980 "Predicted intracellular proteins" "Endocytosis, Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 216.0;Kupffer cells: 301.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Not detected" "Not detected" "CAB020679, HPA051187, HPA076450" Approved Supported Vesicles,Cytosol NA NA 33000 "Cluster 25: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 18: Liver cancer - Metabolism" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 29 "Vesicles, Cytosol" "CAB020679: , HPA051187: , HPA076450: " "unprognostic (7.25e-2)" "unprognostic (8.58e-2)" "unprognostic (3.59e-2)" "unprognostic (5.39e-3)" "unprognostic (7.80e-2)" "unprognostic (5.67e-2)" "unprognostic (2.75e-1)" "unprognostic (1.57e-1)" "unprognostic (4.61e-2)" "potential prognostic unfavorable (1.11e-4)" "potential prognostic favorable (3.10e-6)" "unprognostic (2.81e-1)" "unprognostic (1.07e-2)" "potential prognostic unfavorable (6.33e-5)" "unprognostic (2.93e-3)" "unprognostic (1.15e-1)" "unprognostic (1.36e-2)" "unprognostic (9.41e-3)" "unprognostic (2.55e-1)" "unprognostic (1.03e-2)" "unprognostic (2.11e-1)" "unprognostic (8.51e-2)" "unprognostic (2.03e-2)" "unprognostic (3.45e-1)" "unprognostic (9.41e-3)" "unprognostic (4.13e-3)" "unprognostic (8.32e-3)" "unprognostic (2.37e-1)" "unprognostic (8.20e-2)" "unprognostic (1.64e-1)" "unprognostic (2.37e-2)" SNX6 ENSG00000129515 "Sorting nexin 6" Q9UNH7 14 34561093-34630160 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 471.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049374 Approved Supported Endosomes,Lysosomes NA NA 33000 "Cluster 35: Neutrophils - Protein binding" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 43 "Endosomes, Lysosomes" "HPA049374: " "unprognostic (8.96e-3)" "unprognostic (3.99e-1)" "unprognostic (3.35e-1)" "unprognostic (3.08e-2)" "unprognostic (6.90e-2)" "unprognostic (1.29e-1)" "unprognostic (8.99e-2)" "unprognostic (1.12e-1)" "unprognostic (4.03e-3)" "unprognostic (4.52e-2)" "potential prognostic favorable (9.01e-5)" "unprognostic (2.19e-1)" "unprognostic (2.19e-1)" "potential prognostic unfavorable (1.43e-4)" "unprognostic (2.99e-2)" "unprognostic (4.23e-3)" "unprognostic (1.07e-2)" "unprognostic (1.29e-1)" "unprognostic (9.43e-3)" "unprognostic (2.33e-2)" "unprognostic (1.76e-2)" "unprognostic (4.81e-3)" "unprognostic (1.12e-3)" "unprognostic (3.58e-1)" "unprognostic (2.81e-1)" "unprognostic (3.41e-3)" "unprognostic (1.21e-1)" "unprognostic (3.66e-2)" "unprognostic (1.78e-1)" "unprognostic (2.11e-2)" "unprognostic (6.87e-2)" SNX7 ENSG00000162627 "Sorting nexin 7" Q9UNH6 1 98661701-98760500 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Thymic myoid cells: 194.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "Gallbladder cancer: 209.1" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037419 Enhanced Approved "Vesicles,Cell Junctions" NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 19: Astrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 62: Smooth muscle cells - Muscle contraction" 10 Vesicles "Cell Junctions" "HPA037419: " "unprognostic (2.17e-1)" "unprognostic (3.21e-1)" "unprognostic (1.83e-1)" "unprognostic (1.86e-1)" "potential prognostic favorable (3.21e-4)" "unprognostic (1.18e-1)" "unprognostic (1.45e-1)" "unprognostic (7.95e-3)" "unprognostic (2.34e-1)" "unprognostic (1.13e-3)" "potential prognostic favorable (3.56e-7)" "unprognostic (6.05e-3)" "unprognostic (2.80e-1)" "validated prognostic unfavorable (2.81e-6)" "validated prognostic unfavorable (2.56e-6)" "potential prognostic unfavorable (8.50e-4)" "unprognostic (3.64e-2)" "unprognostic (1.02e-1)" "unprognostic (6.92e-3)" "unprognostic (8.99e-2)" "unprognostic (2.03e-1)" "unprognostic (5.13e-3)" "unprognostic (3.40e-1)" "unprognostic (2.79e-1)" "unprognostic (5.13e-3)" "unprognostic (3.99e-2)" "unprognostic (2.51e-1)" "unprognostic (1.81e-1)" "unprognostic (2.37e-1)" "unprognostic (3.34e-1)" "unprognostic (1.60e-1)" SNX8 Mvp1 ENSG00000106266 "Sorting nexin 8" Q9Y5X2 7 2251770-2354318 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "cDC: 176.2;Esophageal apical cells: 130.5;Hofbauer cells: 215.4;Late spermatids: 485.5;Macrophages: 152.8;Retinal horizontal cells: 128.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Lung - Macrophages, Skin - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057296, HPA060194" Approved Supported Vesicles NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 55: Lymphoma - Immune response" "Cluster 82: Dendritic cells - Antigen presentation" 6 Vesicles "HPA057296: , HPA060194: " "unprognostic (9.22e-2)" "unprognostic (6.58e-2)" "unprognostic (2.68e-1)" "unprognostic (3.89e-1)" "unprognostic (1.61e-1)" "unprognostic (1.43e-1)" "unprognostic (3.90e-3)" "unprognostic (3.86e-2)" "unprognostic (3.73e-1)" "unprognostic (1.40e-3)" "unprognostic (1.17e-3)" "unprognostic (8.32e-2)" "unprognostic (2.34e-1)" "validated prognostic unfavorable (1.80e-5)" "validated prognostic unfavorable (2.40e-4)" "unprognostic (1.24e-2)" "unprognostic (9.27e-3)" "unprognostic (7.85e-2)" "unprognostic (1.12e-1)" "unprognostic (3.80e-2)" "unprognostic (6.83e-2)" "unprognostic (7.81e-2)" "unprognostic (3.22e-3)" "unprognostic (1.05e-1)" "unprognostic (2.16e-1)" "unprognostic (1.26e-1)" "unprognostic (9.80e-2)" "unprognostic (5.48e-2)" "unprognostic (2.28e-1)" "unprognostic (2.33e-2)" "unprognostic (2.44e-2)" SNX9 "SDP1, SH3PX1, SH3PXD3A" ENSG00000130340 "Sorting nexin 9" Q9Y5X1 6 157700387-157945077 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Endocytosis, Mitosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 2921.6;Endometrial luminal cells: 2424.3;Esophageal apical cells: 1151.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 10.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031410, HPA057203" Approved Supported "Plasma membrane,Cytosol" No No 120000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 51: Secretory epithelial cells - Mixed function" 53 "Plasma membrane" Cytosol "HPA031410: , HPA057203: " "unprognostic (4.25e-3)" "potential prognostic unfavorable (8.10e-4)" "unprognostic (5.58e-3)" "unprognostic (2.42e-3)" "unprognostic (7.14e-2)" "unprognostic (2.25e-2)" "unprognostic (9.60e-2)" "unprognostic (3.03e-3)" "unprognostic (6.28e-3)" "unprognostic (1.59e-2)" "potential prognostic favorable (3.89e-6)" "unprognostic (2.61e-3)" "unprognostic (3.97e-1)" "unprognostic (6.22e-2)" "unprognostic (2.13e-1)" "unprognostic (1.02e-3)" "unprognostic (1.77e-2)" "unprognostic (2.82e-2)" "unprognostic (1.21e-1)" "unprognostic (3.55e-3)" "unprognostic (1.07e-2)" "unprognostic (7.23e-2)" "unprognostic (9.50e-2)" "unprognostic (7.96e-2)" "unprognostic (2.05e-1)" "potential prognostic favorable (5.97e-4)" "unprognostic (7.71e-2)" "unprognostic (1.98e-1)" "unprognostic (1.98e-1)" "unprognostic (2.40e-2)" "unprognostic (1.52e-1)" SOAT1 "ACAT, ACAT1, SOAT, STAT" ENSG00000057252 "Sterol O-acyltransferase 1" P35610 1 179293714-179358680 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Acyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "adrenal gland: 155.9" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 897.6;monocytes: 223.9;Salivary acinar cells: 243.9" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 178.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adrenal gland - Adrenal cortex cells, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells, Testis - Leydig cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009533, HPA047171" Enhanced Enhanced "Endoplasmic reticulum" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 18: Adrenal cortex cells - Steroidogensis" 36 "Endoplasmic reticulum" "CAB009533: , HPA047171: " "unprognostic (3.57e-1)" "unprognostic (3.25e-1)" "unprognostic (2.34e-1)" "unprognostic (2.63e-2)" "unprognostic (2.28e-1)" "unprognostic (4.04e-2)" "unprognostic (7.63e-2)" "unprognostic (9.93e-3)" "unprognostic (1.39e-1)" "unprognostic (4.09e-2)" "potential prognostic favorable (3.14e-4)" "unprognostic (3.23e-1)" "unprognostic (6.31e-2)" "unprognostic (7.70e-3)" "unprognostic (4.13e-3)" "unprognostic (1.20e-2)" "unprognostic (3.98e-2)" "unprognostic (4.05e-2)" "unprognostic (3.82e-3)" "unprognostic (4.48e-2)" "unprognostic (1.21e-3)" "unprognostic (3.27e-1)" "unprognostic (2.49e-1)" "unprognostic (3.59e-1)" "unprognostic (1.07e-1)" "unprognostic (2.90e-1)" "unprognostic (8.07e-2)" "unprognostic (9.52e-3)" "unprognostic (2.03e-1)" "unprognostic (9.51e-2)" "unprognostic (2.26e-1)" SOAT2 ACAT2 ENSG00000167780 "Sterol O-acyltransferase 2" O75908 12 53103486-53124535 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "intestine: 18.3" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 5.4;Enterocytes: 19.0;Epididymal basal cells: 4.3;Fibro-adipogenic progenitors: 7.6;Medullary thymic epithelial cells: 7.2;Schwann cells: 3.1;T-cells: 2.7;Thymic myoid cells: 2.7;Thymocytes: 4.2" "Group enriched" "Detected in some" 6 "fibroblast: 2.4;leukocyte: 6.4" "Group enriched" "Detected in some" 6 "Liver Hepatocellular Carcinoma (TCGA): 6.4;Testicular Germ Cell Tumor (TCGA): 5.5" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "MAIT T-cell: 1.1" "Lineage enriched" "Detected in single" 6 "T-cells: 1.1" "Cancer enhanced" "Detected in some" "liver cancer: 5.5" "Liver - Hepatocytes, Spleen - Fibroblasts_2" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 27: T-cells - Unknown function" "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 18: Liver cancer - Metabolism" "Cluster 1: Enterocytes - Absorption and Digestion" 2 "unprognostic (1.38e-1)" "unprognostic (6.20e-2)" "unprognostic (1.85e-3)" "unprognostic (2.19e-1)" SOBP FLJ10159 ENSG00000112320 "Sine oculis binding protein homolog" A7XYQ1 6 107490106-107661306 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bergmann glia: 460.5;Brain excitatory neurons: 320.9;Fibro-adipogenic progenitors: 340.6;Lactotrophs: 399.9;Medullary thymic epithelial cells: 316.8;Oligodendrocyte progenitor cells: 356.4;Pituitary stem cells: 345.1;Thyrotrophs: 406.7" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 9.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.3" "Lineage enriched" "Detected in single" 13 "B-cells: 1.3" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029242 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 18: Non-specific - Translation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 51: Neurons - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 3 Nucleoplasm Vesicles "HPA029242: " "unprognostic (2.15e-1)" "unprognostic (1.98e-1)" "unprognostic (1.41e-1)" "unprognostic (1.60e-3)" "unprognostic (3.10e-1)" "unprognostic (3.21e-1)" "unprognostic (1.16e-1)" "validated prognostic favorable (2.68e-4)" "validated prognostic favorable (1.01e-4)" "unprognostic (8.00e-3)" "unprognostic (1.17e-2)" "unprognostic (1.33e-1)" "unprognostic (8.53e-2)" "unprognostic (1.66e-1)" "unprognostic (8.61e-2)" "unprognostic (1.41e-1)" "unprognostic (2.95e-2)" "potential prognostic favorable (2.48e-5)" "unprognostic (4.00e-1)" "unprognostic (1.34e-1)" "unprognostic (6.77e-2)" "unprognostic (2.11e-1)" "unprognostic (5.77e-2)" "unprognostic (1.13e-1)" "unprognostic (4.32e-2)" "unprognostic (1.54e-1)" SOCS1 "Cish1, JAB, SOCS-1, SSI-1, TIP3" ENSG00000185338 "Suppressor of cytokine signaling 1" O15524 16 11254417-11256204 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Growth regulation, Ubl conjugation pathway" "Signal transduction inhibitor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast lactating cells: 91.1;Early spermatids: 85.6;Epididymal basal cells: 139.7;Innate lymphoid cells: 179.2;Mast cells: 265.4;NK-cells: 133.3;Pancreatic islet cells: 182.5;Syncytiotrophoblasts: 85.1;T-cells: 137.2" "Cell type enriched" "Detected in many" 4 "leukocyte: 41.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 13.8" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "lymphoma: 22.6" "Liver - Neutrophils" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB010355, HPA074108" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 25: Non-specific - Transcription" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 20: Non-specific - Transcription regulation" 68 Nucleoplasm Vesicles "CAB010355: , HPA074108: " "unprognostic (2.24e-2)" "unprognostic (9.35e-3)" "unprognostic (4.55e-2)" "unprognostic (2.57e-2)" "unprognostic (1.54e-1)" "unprognostic (3.23e-1)" "unprognostic (6.23e-3)" "unprognostic (1.09e-3)" "unprognostic (1.13e-3)" "unprognostic (1.43e-2)" "potential prognostic unfavorable (2.56e-6)" "unprognostic (2.75e-1)" "unprognostic (7.81e-2)" "unprognostic (1.34e-2)" "unprognostic (1.73e-1)" "unprognostic (8.01e-2)" "unprognostic (2.00e-1)" "unprognostic (2.33e-2)" "unprognostic (2.53e-3)" "unprognostic (3.05e-1)" "unprognostic (5.48e-3)" "unprognostic (1.33e-1)" "unprognostic (2.25e-2)" "unprognostic (1.60e-1)" "unprognostic (1.80e-1)" "unprognostic (2.61e-1)" "potential prognostic favorable (6.20e-6)" "unprognostic (1.57e-1)" "unprognostic (2.00e-3)" "unprognostic (4.50e-2)" "unprognostic (4.09e-1)" SOCS2 "CIS2, Cish2, SOCS-2, SSI-2, SSI2, STATI2" ENSG00000120833 "Suppressor of cytokine signaling 2" O14508 12 93569814-93583487 "Predicted intracellular proteins" "Growth regulation, Ubl conjugation pathway" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 187.5;Hematopoietic stem cells: 164.5;Lymphatic endothelial cells: 99.9;Peritubular myoid cells: 92.5;Pituitary stem cells: 130.1;Platelets: 94.7;Prostatic glandular cells: 136.0;Vascular endothelial cells: 128.1" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 75.1" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 92.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 178.7" "Lineage enriched" "Detected in many" 5 "granulocytes: 178.7" "Cancer enhanced" "Detected in all" "Leukemia: 96.0" "Heart muscle - Endothelial cells, Kidney - Endothelial cells, Minor Salivary Gland - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010356 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 75: Ovary - Mixed function" "Cluster 44: Non-specific - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 69 "Endoplasmic reticulum" "CAB010356: " "unprognostic (1.38e-1)" "unprognostic (9.30e-2)" "unprognostic (2.20e-2)" "unprognostic (2.06e-2)" "unprognostic (2.97e-1)" "unprognostic (5.07e-2)" "unprognostic (1.74e-1)" "unprognostic (2.27e-2)" "unprognostic (7.42e-3)" "unprognostic (2.69e-1)" "validated prognostic favorable (2.85e-9)" "validated prognostic favorable (7.93e-5)" "unprognostic (4.21e-2)" "validated prognostic favorable (9.13e-8)" "validated prognostic favorable (1.74e-4)" "unprognostic (2.68e-1)" "unprognostic (1.39e-1)" "unprognostic (2.35e-2)" "unprognostic (1.94e-1)" "unprognostic (2.09e-2)" "unprognostic (2.61e-1)" "potential prognostic favorable (1.72e-5)" "unprognostic (1.16e-1)" "unprognostic (3.82e-1)" "unprognostic (1.87e-2)" "unprognostic (1.77e-1)" "unprognostic (1.52e-1)" "unprognostic (1.29e-2)" "unprognostic (3.09e-1)" "unprognostic (4.60e-2)" "unprognostic (1.53e-1)" SOCS3 "CIS3, Cish3, SOCS-3, SSI-3" ENSG00000184557 "Suppressor of cytokine signaling 3" O14543 17 78356778-78360077 "Disease related genes, Predicted intracellular proteins" "Growth regulation, Ubl conjugation pathway" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 480.4" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 909.4;Epididymal basal cells: 516.4;Fibroblasts: 407.7;Medullary thymic epithelial cells: 482.4;monocytes: 413.1;Neutrophils: 406.0;Pericytes: 503.7;Schwann cells: 420.8;Smooth muscle cells: 597.8;Vascular endothelial cells: 754.5;Vascular smooth muscle cells: 408.7" "Group enriched" "Detected in some" 5 "endothelial cell: 54.3;vascular associated smooth muscle cell: 14.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 9.6" "Group enriched" "Detected in many" 6 "granulocytes: 9.6;T-cells: 3.1" "Low cancer specificity" "Detected in all" "Colon - Neutrophils, Liver - Neutrophils, Testis - Endothelial cells" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 5 "spinal cord: 12.9" "CAB012220, HPA068569" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 12: Non-specific - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 44 Cytosol "Plasma membrane" "CAB012220: , HPA068569: " "unprognostic (1.82e-2)" "potential prognostic favorable (3.14e-4)" "unprognostic (3.43e-2)" "unprognostic (1.91e-2)" "unprognostic (1.11e-1)" "unprognostic (1.24e-1)" "validated prognostic unfavorable (6.78e-4)" "validated prognostic unfavorable (5.78e-4)" "unprognostic (7.32e-3)" "unprognostic (6.46e-2)" "potential prognostic unfavorable (2.94e-4)" "unprognostic (1.32e-2)" "unprognostic (4.14e-2)" "unprognostic (1.10e-1)" "unprognostic (9.05e-2)" "unprognostic (2.95e-1)" "unprognostic (1.02e-2)" "unprognostic (2.80e-2)" "unprognostic (3.60e-1)" "unprognostic (2.62e-3)" "unprognostic (7.87e-2)" "unprognostic (9.79e-2)" "unprognostic (2.39e-1)" "unprognostic (3.43e-3)" "unprognostic (3.13e-2)" "unprognostic (8.49e-3)" "unprognostic (3.71e-2)" "unprognostic (8.88e-3)" "unprognostic (1.44e-1)" "potential prognostic unfavorable (8.55e-4)" "unprognostic (6.39e-2)" SOCS4 SOCS7 ENSG00000180008 "Suppressor of cytokine signaling 4" Q8WXH5 14 55027230-55049489 "Predicted intracellular proteins" "Growth regulation, Ubl conjugation pathway" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 27.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013478, HPA057961" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 44: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 17: Non-specific - RNA processing" 28 "Nucleoplasm, Cytosol" "CAB013478: , HPA057961: " "unprognostic (6.36e-3)" "potential prognostic unfavorable (3.91e-4)" "unprognostic (3.13e-1)" "unprognostic (3.24e-2)" "unprognostic (6.43e-2)" "unprognostic (4.77e-2)" "unprognostic (6.72e-3)" "unprognostic (1.35e-1)" "unprognostic (4.47e-2)" "potential prognostic unfavorable (7.45e-4)" "potential prognostic favorable (9.35e-4)" "unprognostic (4.08e-3)" "unprognostic (1.43e-1)" "unprognostic (1.78e-3)" "unprognostic (1.09e-1)" "unprognostic (3.90e-2)" "unprognostic (3.27e-1)" "unprognostic (7.87e-2)" "potential prognostic favorable (5.97e-4)" "unprognostic (5.06e-2)" "unprognostic (1.62e-2)" "unprognostic (3.69e-1)" "unprognostic (4.13e-2)" "unprognostic (2.27e-2)" "unprognostic (1.82e-1)" "unprognostic (4.88e-2)" "unprognostic (6.51e-2)" "unprognostic (3.08e-1)" "unprognostic (2.63e-1)" "unprognostic (1.51e-2)" "unprognostic (3.40e-1)" SOCS5 "CIS6, Cish5, CISH6, KIAA0671, SOCS-5" ENSG00000171150 "Suppressor of cytokine signaling 5" O75159 2 46698952-46780245 "Predicted intracellular proteins" "Growth regulation, Ubl conjugation pathway" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Distal convoluted tubule cells: 50.2;Loop of henle epithelial cells: 45.4;Papillary tip epithelial cells: 28.6;Podocytes: 51.4;Proximal tubule cells: 39.6;Renal collecting duct intercalated cells: 40.4;Renal collecting duct principal cells: 31.9;Renal connecting tubule cells: 40.0" "Cell type enhanced" "Detected in single" "upper rhombic lip: 1.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020884, CAB025510" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" No No "Cluster 3: Non-specific - Nuclear processes" "Cluster 61: Non-specific - Transcription" "Cluster 2: Neurons - Nucleosome" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 105: Non-specific - Mixed function" 4 Cytosol "Nucleoplasm, Plasma membrane" "CAB025510: , HPA020884: " "unprognostic (6.74e-3)" "unprognostic (2.85e-1)" "unprognostic (1.48e-1)" "unprognostic (1.56e-3)" "unprognostic (1.04e-1)" "unprognostic (2.11e-2)" "unprognostic (1.39e-1)" "unprognostic (1.23e-1)" "unprognostic (2.88e-1)" "unprognostic (4.48e-2)" "validated prognostic favorable (7.01e-5)" "validated prognostic favorable (2.02e-4)" "unprognostic (2.82e-1)" "potential prognostic unfavorable (7.78e-4)" "unprognostic (1.12e-2)" "unprognostic (8.80e-2)" "unprognostic (2.06e-3)" "unprognostic (1.85e-2)" "unprognostic (2.62e-1)" "unprognostic (7.13e-3)" "unprognostic (1.55e-2)" "potential prognostic unfavorable (9.33e-4)" "unprognostic (1.06e-1)" "unprognostic (1.31e-1)" "unprognostic (1.88e-1)" "unprognostic (4.84e-2)" "unprognostic (8.74e-2)" "unprognostic (5.13e-2)" "unprognostic (4.63e-1)" "unprognostic (5.97e-2)" "unprognostic (1.39e-1)" SOCS6 "CIS4, Cish4, HSPC060, SOCS4, SSI4, STAI4, STATI4" ENSG00000170677 "Suppressor of cytokine signaling 6" O14544 18 70289045-70330199 "Predicted intracellular proteins" "Growth regulation, Ubl conjugation pathway" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Microglia: 554.2" "Cell type enriched" "Detected in all" 11 "central nervous system macrophage: 633.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 3.6;myeloid DC: 3.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010189 Approved Approved "Nuclear speckles,Cytosol" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 7: Liver cancer - Metabolism" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 98 "Nuclear speckles" Cytosol "CAB010189: " "unprognostic (7.17e-2)" "unprognostic (3.26e-3)" "unprognostic (2.75e-1)" "unprognostic (3.78e-3)" "unprognostic (5.82e-3)" "unprognostic (2.06e-1)" "unprognostic (1.61e-1)" "unprognostic (7.38e-2)" "unprognostic (2.93e-1)" "unprognostic (8.24e-2)" "validated prognostic favorable (2.53e-9)" "validated prognostic favorable (1.68e-4)" "unprognostic (3.62e-2)" "unprognostic (4.85e-2)" "unprognostic (8.20e-2)" "unprognostic (1.56e-2)" "unprognostic (1.12e-1)" "unprognostic (7.66e-2)" "unprognostic (2.88e-2)" "unprognostic (2.27e-1)" "unprognostic (5.50e-2)" "unprognostic (2.97e-3)" "unprognostic (1.76e-1)" "unprognostic (1.28e-1)" "unprognostic (5.90e-3)" "unprognostic (1.80e-2)" "unprognostic (9.98e-3)" "unprognostic (2.29e-1)" "unprognostic (4.17e-1)" "unprognostic (5.57e-3)" "unprognostic (1.02e-1)" SOCS7 "NAP4, NCKAP4" ENSG00000274211 "Suppressor of cytokine signaling 7" O14512 17 38351844-38405593 "Predicted intracellular proteins" "Growth regulation, Ubl conjugation pathway" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "brain: 42.7;testis: 69.2" "Group enriched" "Detected in many" 5 "Early spermatids: 237.6;Late spermatids: 569.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004475 Approved Approved Cytosol NA NA "Cluster 67: Testis - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 23 Cytosol "HPA004475: " "unprognostic (5.77e-2)" "unprognostic (1.45e-2)" "unprognostic (1.25e-1)" "unprognostic (2.43e-2)" "unprognostic (1.20e-1)" "unprognostic (4.94e-2)" "unprognostic (3.02e-1)" "unprognostic (7.93e-2)" "unprognostic (3.66e-1)" "potential prognostic favorable (5.90e-4)" "unprognostic (1.21e-2)" "unprognostic (1.83e-1)" "unprognostic (1.05e-2)" "unprognostic (1.27e-2)" "unprognostic (1.01e-1)" "unprognostic (5.56e-2)" "unprognostic (3.57e-2)" "unprognostic (1.94e-3)" "unprognostic (1.72e-2)" "unprognostic (3.60e-2)" "unprognostic (2.48e-1)" "unprognostic (1.10e-2)" "unprognostic (1.63e-2)" "unprognostic (1.66e-2)" "unprognostic (1.77e-3)" "unprognostic (1.37e-1)" "unprognostic (5.93e-2)" "unprognostic (1.48e-1)" SOD1 "ALS, ALS1, IPOA" ENSG00000142168 "Superoxide dismutase 1" P00441 21 31659666-31668931 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Antioxidant, Oxidoreductase" "Amyotrophic lateral sclerosis, Cancer-related genes, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1537.1" "Cell type enhanced" "Detected in all" "Gastric progenitor cells: 1937.9;Hepatocytes: 3764.4;Late spermatids: 1476.3;Oocytes: 1662.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001401, CAB008670" Enhanced Enhanced Nucleoplasm,Cytosol NA NA 52000000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 76: Non-specific - Metabolism" "Cluster 27: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 93: Hepatocytes - Bile production & excretion" 119 Nucleoplasm Cytosol "CAB008670: , HPA001401: " "unprognostic (1.06e-1)" "unprognostic (2.88e-3)" "unprognostic (9.12e-2)" "unprognostic (3.54e-3)" "unprognostic (2.55e-1)" "unprognostic (2.74e-2)" "unprognostic (4.06e-2)" "unprognostic (1.42e-1)" "unprognostic (3.08e-3)" "unprognostic (1.63e-1)" "unprognostic (1.33e-2)" "unprognostic (1.96e-1)" "unprognostic (1.54e-3)" "unprognostic (1.04e-1)" "unprognostic (2.05e-2)" "unprognostic (4.03e-3)" "unprognostic (3.70e-2)" "unprognostic (6.53e-3)" "unprognostic (4.46e-2)" "unprognostic (2.05e-1)" "unprognostic (1.03e-1)" "unprognostic (1.05e-1)" "unprognostic (1.53e-3)" "unprognostic (1.46e-1)" "unprognostic (1.98e-2)" "unprognostic (9.22e-2)" "unprognostic (3.10e-1)" "unprognostic (2.70e-2)" "unprognostic (1.22e-2)" "unprognostic (4.18e-2)" "unprognostic (1.07e-1)" SOD2 "GC1, GClnc1, IPOB, MnSOD" ENSG00000291237 "Superoxide dismutase 2" P04179 6 159669069-159762529 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 1021.8" "Cell type enhanced" "Detected in all" "Endometrial glandular cells: 3029.5;Epicardial cells: 3625.0;monocytes: 4200.9;Neutrophils: 12523.7;Pancreatic acinar cells: 3477.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 10 "neutrophil: 4504.9" "Lineage enriched" "Detected in all" 10 "granulocytes: 4504.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001814 Supported Supported Mitochondria NA NA 25000000 "Cluster 4: Neutrophils - Degranulation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 9 Mitochondria "HPA001814: " SOD3 EC-SOD ENSG00000109610 "Superoxide dismutase 3" P08294 4 24789912-24800842 "Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Antioxidant, Heparin-binding, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "blood vessel: 827.8;choroid plexus: 1058.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 197.9;Cytotrophoblasts: 258.2;Decidual stromal cells: 196.6;Epididymal basal cells: 281.6;Fallopian tube ciliated cells: 928.4;Fibroblasts: 414.5;Leydig cells: 254.4;Pancreatic duct cells: 404.5;Pericytes: 266.7;Peritubular myoid cells: 325.1;Syncytiotrophoblasts: 270.9;Vascular smooth muscle cells: 716.4" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 197.5;vascular associated smooth muscle cell: 287.8" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 10 "choroid plexus: 887.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Fibroblasts, Skin - Fibroblasts_2, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042110 Supported "Secreted to blood" Enzyme NA NA 50400000 180000000 "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 6 "HPA042110: " "unprognostic (1.10e-2)" "unprognostic (7.85e-2)" "unprognostic (4.17e-2)" "unprognostic (4.12e-2)" "unprognostic (4.66e-1)" "unprognostic (1.62e-1)" "unprognostic (4.37e-2)" "potential prognostic unfavorable (4.52e-4)" "unprognostic (1.25e-2)" "unprognostic (6.20e-2)" "unprognostic (1.83e-3)" "unprognostic (2.23e-2)" "unprognostic (1.75e-1)" "unprognostic (1.58e-1)" "unprognostic (7.72e-2)" "unprognostic (3.36e-3)" "unprognostic (7.58e-3)" "unprognostic (1.97e-3)" "unprognostic (5.07e-2)" "unprognostic (1.52e-1)" "unprognostic (5.71e-2)" "unprognostic (4.74e-2)" "unprognostic (4.40e-2)" "unprognostic (1.64e-1)" "unprognostic (6.53e-2)" "unprognostic (2.50e-1)" "unprognostic (3.28e-1)" "unprognostic (7.47e-2)" "unprognostic (1.47e-1)" "unprognostic (1.18e-1)" "unprognostic (2.33e-1)" SOGA1 "C20orf117, dJ132F21.1, FLJ44670, KIAA0889, SOGA" ENSG00000149639 "Suppressor of glucose, autophagy associated 1" O94964 20 36777447-36863538 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 70.6" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 127.8;Oligodendrocytes: 143.9;Sertoli cells: 184.4" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 319.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Prostate - Smooth muscle cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043992 Approved Approved Nucleoli,Cytosol "Secreted to blood" Other NA Yes "Cluster 71: Cerebellum - Nervous system development" "Cluster 15: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 25 "Nucleoli, Cytosol" "HPA043992: " "unprognostic (3.34e-1)" "unprognostic (7.94e-3)" "unprognostic (7.45e-2)" "unprognostic (3.12e-2)" "unprognostic (2.53e-1)" "unprognostic (1.12e-1)" "unprognostic (4.26e-2)" "unprognostic (7.37e-2)" "unprognostic (8.95e-2)" "potential prognostic favorable (5.03e-4)" "unprognostic (1.37e-2)" "unprognostic (2.53e-1)" "unprognostic (2.92e-3)" "unprognostic (2.16e-1)" "unprognostic (7.96e-2)" "unprognostic (6.19e-3)" "unprognostic (5.89e-3)" "potential prognostic unfavorable (1.85e-4)" "unprognostic (3.83e-1)" "unprognostic (2.16e-2)" "unprognostic (6.21e-3)" "unprognostic (2.22e-1)" "unprognostic (5.67e-2)" "unprognostic (3.24e-2)" "unprognostic (3.77e-1)" "unprognostic (7.50e-2)" "unprognostic (2.33e-2)" "unprognostic (9.60e-3)" "unprognostic (1.74e-2)" SOGA3 "C6orf174, dJ403A15.3" ENSG00000214338 "SOGA family member 3" Q5TF21 6 127472806-127519335 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 7.7" "Group enriched" "Detected in some" 6 "Bergmann glia: 36.3;Brain excitatory neurons: 58.4;Brain inhibitory neurons: 53.2;Oligodendrocyte progenitor cells: 35.6;Oligodendrocytes: 21.3;Other brain neurons: 57.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Kidney Renal Papillary Cell Carcinoma (TCGA): 2.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Neuroblastoma: 45.6" "Lung - Alveolar cells type 1, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035388, HPA035389" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 37: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 4 "Nucleoplasm, Cytosol" "HPA035388: , HPA035389: " "unprognostic (2.78e-1)" "unprognostic (4.18e-3)" "unprognostic (3.88e-2)" "unprognostic (1.61e-2)" "unprognostic (2.69e-1)" "unprognostic (2.25e-1)" SOHLH1 "bA100C15.3, bHLHe80, C9orf157, NOHLH, SPATA27, TEB2" ENSG00000165643 "Spermatogenesis and oogenesis specific basic helix-loop-helix 1" Q5JUK2 9 135693407-135704498 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 46.2;testis: 23.9" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 110.8;Early primary spermatocytes: 23.7;Late primary spermatocytes: 12.7;Oocytes: 82.9;Undifferentiated spermatogonia: 57.6" "Cell type enhanced" "Detected in many" "hippocampal CA1-3: 22.2" "Group enriched" "Detected in some" 7 "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 6.4;Head and Neck Squamous Cell Carcinoma (TCGA): 5.8;Lung Squamous Cell Carcinoma (TCGA): 10.6;Uterine Corpus Endometrial Carcinoma (TCGA): 3.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 3.0;Myeloma: 9.3" "Not detected" "Not detected" HPA059439 Approved "Nuclear speckles" NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 24: Neurons - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 23 "Nuclear speckles" "HPA059439: " "unprognostic (2.82e-1)" "unprognostic (1.11e-1)" "unprognostic (9.67e-2)" "unprognostic (4.85e-1)" "unprognostic (1.06e-1)" SOHLH2 "bHLHe81, FLJ20449, SPATA28, TEB1" ENSG00000120669 "Spermatogenesis and oogenesis specific basic helix-loop-helix 2" Q9NX45 13 36168217-36214588 "Predicted intracellular proteins, Transcription factors" "Differentiation, Oogenesis, Spermatogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 25.8" "Group enriched" "Detected in some" 4 "Late spermatids: 125.3;Oocytes: 409.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skin - Inner root sheath cells, Skin - Outer root sheath cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA029182 Uncertain Vesicles NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 34: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 41: Oocytes - Oogenesis" Vesicles "HPA029182: " "unprognostic (4.41e-3)" "unprognostic (4.36e-2)" "unprognostic (9.43e-2)" "unprognostic (4.88e-2)" "unprognostic (2.55e-1)" "unprognostic (7.38e-2)" "unprognostic (4.31e-2)" "unprognostic (1.31e-1)" "unprognostic (1.97e-1)" "unprognostic (2.78e-1)" "unprognostic (1.17e-1)" "unprognostic (6.20e-2)" "unprognostic (4.37e-2)" "unprognostic (1.20e-1)" SON "BASS1, C21orf50, DBP-5, FLJ21099, FLJ33914, KIAA1019, NREBP" ENSG00000159140 "SON DNA and RNA binding protein" P18583 21 33543038-33577481 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Cell cycle, mRNA processing, mRNA splicing" "DNA-binding, RNA-binding" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023535, HPA031755, HPA031756" Supported Enhanced "Nuclear speckles" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 15: Bone marrow - Innate immune response" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 47: Leukemia - Hemostasis" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 39 "Nuclear speckles" "HPA023535: , HPA031755: , HPA031756: " "unprognostic (1.58e-1)" "unprognostic (5.99e-3)" "unprognostic (5.36e-2)" "unprognostic (3.56e-2)" "unprognostic (3.39e-1)" "unprognostic (4.22e-2)" "unprognostic (6.51e-2)" "unprognostic (1.99e-1)" "unprognostic (1.66e-1)" "unprognostic (1.26e-1)" "potential prognostic favorable (8.30e-5)" "unprognostic (5.04e-3)" "unprognostic (3.08e-1)" "unprognostic (1.70e-2)" "unprognostic (2.61e-1)" "unprognostic (6.86e-2)" "unprognostic (6.64e-2)" "unprognostic (4.40e-1)" "unprognostic (4.43e-2)" "unprognostic (1.52e-2)" "unprognostic (5.47e-2)" "unprognostic (1.82e-1)" "unprognostic (1.32e-1)" "unprognostic (1.03e-1)" "unprognostic (2.97e-1)" "unprognostic (1.21e-2)" "unprognostic (1.42e-1)" "unprognostic (7.67e-2)" "unprognostic (6.31e-2)" "unprognostic (4.88e-2)" "unprognostic (1.26e-1)" SORBS1 "CAP, FLJ12406, KIAA1296, ponsin, SH3D5, sh3p12" ENSG00000095637 "Sorbin and SH3 domain containing 1" Q9BX66 10 95311771-95561414 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 482.7" "Cell type enhanced" "Detected in many" "Adipocytes: 1968.4;Astrocytes: 1464.9;Bergmann glia: 1572.2;Cardiomyocytes: 2244.5;Ependymal cells: 1443.6;Hepatic stellate cells: 884.3;Myonuclei: 1611.1;Salivary myoepithelial cells: 1156.8;Smooth muscle cells: 2332.4;Vascular smooth muscle cells: 865.4" "Cell type enhanced" "Detected in all" "astrocyte: 2090.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "basophil: 6.1" "Lineage enriched" "Detected in single" 10 "granulocytes: 6.1" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Smooth muscle cells, Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027559, CAB032850, HPA043084" Enhanced Supported "Plasma membrane,Focal adhesion sites,Centrosome" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 32: Non-specific - Cell proliferation" "Cluster 62: Smooth muscle cells - Muscle contraction" 22 "Focal adhesion sites" "Plasma membrane, Centrosome" "CAB032850: , HPA027559: , HPA043084: " "unprognostic (7.27e-3)" "unprognostic (4.37e-3)" "unprognostic (1.04e-1)" "unprognostic (4.30e-1)" "unprognostic (2.54e-2)" "unprognostic (2.09e-1)" "unprognostic (1.58e-1)" "unprognostic (2.84e-3)" "unprognostic (1.94e-1)" "unprognostic (2.63e-2)" "potential prognostic favorable (4.07e-7)" "unprognostic (4.03e-3)" "unprognostic (3.51e-1)" "unprognostic (3.63e-2)" "unprognostic (2.66e-3)" "unprognostic (5.56e-2)" "unprognostic (2.79e-1)" "unprognostic (6.91e-3)" "unprognostic (4.73e-2)" "unprognostic (4.72e-3)" "potential prognostic unfavorable (4.91e-5)" "unprognostic (1.26e-2)" "unprognostic (2.73e-1)" "unprognostic (1.34e-1)" "unprognostic (8.76e-2)" "unprognostic (2.83e-3)" "unprognostic (5.87e-3)" "unprognostic (2.71e-2)" "unprognostic (1.84e-1)" "unprognostic (1.30e-2)" "unprognostic (1.70e-1)" SORBS2 "ARGBP2, KIAA0777" ENSG00000154556 "Sorbin and SH3 domain containing 2" O94875 4 185585444-185956652 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 601.0" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 3606.0;Adrenal medulla cells: 1872.1;Cardiomyocytes: 3781.8;Müller glia: 1507.0;Rod photoreceptor cells: 2067.5;Vascular smooth muscle cells: 1893.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Rhabdoid: 84.2" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Kidney - Fibroblasts, Liver - Hepatocytes, Prostate - Smooth muscle cells, Spleen - Fibroblasts_1, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 33: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 32 "unprognostic (5.05e-2)" "unprognostic (8.94e-2)" "unprognostic (3.03e-1)" "unprognostic (6.84e-2)" "unprognostic (2.18e-2)" "unprognostic (8.59e-2)" "unprognostic (3.23e-2)" "unprognostic (7.99e-2)" "unprognostic (1.65e-1)" "unprognostic (1.20e-1)" "validated prognostic favorable (1.61e-12)" "validated prognostic favorable (7.20e-4)" "unprognostic (2.35e-2)" "unprognostic (1.47e-3)" "potential prognostic favorable (2.92e-5)" "unprognostic (2.24e-1)" "unprognostic (2.57e-2)" "unprognostic (3.26e-2)" "unprognostic (1.02e-1)" "unprognostic (2.20e-2)" "unprognostic (5.77e-2)" "unprognostic (5.43e-2)" "unprognostic (2.32e-1)" "unprognostic (8.62e-2)" "unprognostic (3.67e-1)" "unprognostic (1.50e-1)" "unprognostic (1.24e-1)" "unprognostic (1.43e-1)" "unprognostic (1.33e-1)" "unprognostic (3.64e-3)" "unprognostic (2.30e-2)" SORBS3 "SCAM-1, SH3D4, vinexin" ENSG00000120896 "Sorbin and SH3 domain containing 3" O60504 8 22544986-22575788 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Late spermatids: 931.3" "Cell type enhanced" "Detected in many" "pericyte: 132.4;vascular associated smooth muscle cell: 117.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Pancreas - Endothelial cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015492, HPA015849" Approved Uncertain "Plasma membrane,Cell Junctions" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 44: Non-specific - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 99 "Cell Junctions" "Plasma membrane" "HPA015492: , HPA015849: " "unprognostic (3.64e-2)" "unprognostic (6.53e-3)" "potential prognostic favorable (1.99e-4)" "unprognostic (8.01e-3)" "unprognostic (3.01e-1)" "unprognostic (1.09e-1)" "unprognostic (2.86e-1)" "unprognostic (1.00e-2)" "unprognostic (2.61e-1)" "unprognostic (2.01e-1)" "unprognostic (5.90e-3)" "unprognostic (2.98e-3)" "unprognostic (1.88e-1)" "unprognostic (8.28e-2)" "unprognostic (3.57e-3)" "unprognostic (1.33e-2)" "unprognostic (3.09e-2)" "unprognostic (2.09e-1)" "unprognostic (8.53e-2)" "unprognostic (5.86e-2)" "unprognostic (9.76e-2)" "unprognostic (1.48e-2)" "unprognostic (1.13e-1)" "unprognostic (1.37e-2)" "unprognostic (6.07e-3)" "potential prognostic favorable (2.52e-5)" "unprognostic (2.39e-1)" "unprognostic (1.34e-1)" "unprognostic (1.87e-1)" "unprognostic (5.29e-2)" "unprognostic (1.61e-1)" SORCS1 ENSG00000108018 "Sortilin related VPS10 domain containing receptor 1" Q8WY21 10 106573663-107164706 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.1;thyroid gland: 10.1" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 180.8;Brain excitatory neurons: 180.2;Brain inhibitory neurons: 508.5;Innate lymphoid cells: 221.0;Melanocytes: 262.8;Müller glia: 586.7;Oligodendrocyte progenitor cells: 494.5;Other brain neurons: 178.0;Proximal tubule cells: 1015.7;Retinal ganglion cells: 320.6;Schwann cells: 1154.2" "Cell type enhanced" "Detected in all" "eccentric medium spiny neuron: 1099.4;medium spiny neuron: 1006.7" "Cancer enhanced" "Detected in some" "Skin Cutaneous Melanoma (TCGA): 8.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 25.9;Sarcoma: 11.8;skin cancer: 10.6" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Skeletal muscle - Fibroblasts, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011948 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 35: Neurons - Synaptic function & neurogenesis" 1 "Plasma membrane, Cytosol" "HPA011948: " "unprognostic (1.24e-2)" "unprognostic (4.06e-1)" "unprognostic (1.05e-1)" "unprognostic (5.13e-2)" "unprognostic (6.55e-2)" "unprognostic (3.09e-2)" "unprognostic (3.76e-1)" SORCS2 KIAA1329 ENSG00000184985 "Sortilin related VPS10 domain containing receptor 2" Q96PQ0 4 7192538-7742836 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.6" "Cell type enhanced" "Detected in many" "Astrocytes: 211.3;Bergmann glia: 184.2;Müller glia: 202.6;Oligodendrocytes: 123.3;Renal collecting duct principal cells: 150.9;Renal connecting tubule cells: 119.8;Retinal amacrine cells: 157.3;Retinal bipolar cells: 517.8;Thyrotrophs: 166.8" "Cell type enhanced" "Detected in all" "deep-layer near-projecting: 430.6;eccentric medium spiny neuron: 372.5" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 19.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Adrenal gland - Fibroblasts, Breast - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071818 Approved Vesicles,Cytosol NA NA "Cluster 65: Brain - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "Vesicles, Cytosol" "HPA071818: " "unprognostic (3.46e-2)" "unprognostic (6.83e-2)" "unprognostic (2.88e-1)" "unprognostic (6.96e-3)" "unprognostic (5.19e-2)" "unprognostic (7.59e-2)" "unprognostic (6.92e-2)" "unprognostic (3.58e-1)" "unprognostic (5.68e-2)" "unprognostic (9.31e-2)" "unprognostic (3.67e-2)" "unprognostic (2.81e-2)" "unprognostic (7.05e-3)" "unprognostic (3.30e-2)" "unprognostic (2.66e-2)" "unprognostic (3.48e-2)" "unprognostic (3.28e-2)" "unprognostic (2.86e-1)" "unprognostic (4.24e-2)" "potential prognostic unfavorable (3.57e-4)" "unprognostic (1.21e-1)" "unprognostic (9.58e-2)" "unprognostic (5.61e-2)" "unprognostic (1.67e-2)" "unprognostic (1.19e-1)" "unprognostic (2.04e-2)" "unprognostic (9.31e-3)" "unprognostic (2.42e-3)" "unprognostic (3.57e-1)" "unprognostic (1.31e-1)" "unprognostic (1.95e-1)" SORCS3 "KIAA1059, SORCS" ENSG00000156395 "Sortilin related VPS10 domain containing receptor 3" Q9UPU3 10 104641290-105265242 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 7.5;pituitary gland: 2.3" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 223.4;Brain excitatory neurons: 191.1;Brain inhibitory neurons: 383.5;Lactotrophs: 147.2;Oligodendrocyte progenitor cells: 592.7;Other brain neurons: 180.0;Pituicytes/FSCs: 89.1;Retinal amacrine cells: 85.1;Somatotrophs: 195.5;Thyrotrophs: 181.1" "Cell type enhanced" "Detected in all" "cerebellar inhibitory: 1181.6" "Group enriched" "Detected in some" 15 "Glioblastoma Multiforme (TCGA): 3.1;Kidney Renal Clear Cell Carcinoma (TCGA): 4.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adrenal gland - Adrenal medulla cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061758 Approved "Plasma membrane" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 35: Neurons - Synaptic function & neurogenesis" 2 "Plasma membrane" "HPA061758: " "unprognostic (2.16e-1)" "unprognostic (1.19e-2)" "unprognostic (2.72e-1)" "unprognostic (2.74e-1)" SORD ENSG00000140263 "Sorbitol dehydrogenase" Q00796 15 45023147-45077185 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 161.0;liver: 253.4;thyroid gland: 99.8" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 892.2;Hepatocytes: 434.7;Prostatic glandular cells: 272.5;Proximal tubule cells: 140.0;Salivary duct cells: 168.3" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Liver Hepatocellular Carcinoma (TCGA): 60.8;Prostate Adenocarcinoma (TCGA): 157.6;Thyroid Carcinoma (TCGA): 73.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 11 "basophil: 87.7;eosinophil: 62.8" "Lineage enriched" "Detected in all" 12 "granulocytes: 87.7" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Breast - Breast glandular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Pituitary gland - Thyrotropes, Prostate - Prostate glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040260, HPA040621" Enhanced Approved "Cytosol,Acrosome,Equatorial segment" NA NA 3600000 "Cluster 22: Eosinophils - Transcription" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 15: Non-specific - Transcription" "Cluster 60: Prostate cancer - Unknown function" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 6 Cytosol "Acrosome, Equatorial segment" "HPA040260: , HPA040621: " "unprognostic (4.10e-2)" "unprognostic (1.82e-1)" "unprognostic (4.18e-2)" "unprognostic (1.66e-3)" "unprognostic (1.22e-1)" "unprognostic (5.03e-2)" "unprognostic (3.74e-1)" "unprognostic (1.65e-2)" "unprognostic (8.73e-3)" "unprognostic (3.61e-2)" "unprognostic (9.16e-2)" "unprognostic (4.27e-1)" "unprognostic (7.49e-3)" "unprognostic (2.24e-3)" "unprognostic (2.72e-2)" "unprognostic (4.02e-3)" "unprognostic (1.09e-2)" "potential prognostic favorable (4.76e-5)" "unprognostic (4.22e-2)" "unprognostic (8.92e-2)" "unprognostic (3.12e-1)" "unprognostic (2.51e-2)" "unprognostic (1.20e-2)" "unprognostic (2.90e-1)" "unprognostic (9.87e-2)" "unprognostic (1.57e-1)" "unprognostic (6.07e-2)" "unprognostic (5.35e-2)" "unprognostic (2.46e-2)" "unprognostic (2.83e-2)" "unprognostic (2.50e-1)" SORL1 "C11orf32, gp250, LR11, LRP9, SorLA, SorLA-1" ENSG00000137642 "Sortilin related receptor 1" Q92673 11 121452314-121633763 "Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Endocytosis, Transport" Receptor "Alzheimer disease, Amyloidosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglia: 2068.7;Neutrophil progenitors: 1032.7;Neutrophils: 4912.5;Pituitary stem cells: 551.2" "Cell type enriched" "Detected in all" 5 "central nervous system macrophage: 2426.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 126.1" "Lineage enriched" "Detected in all" 4 "granulocytes: 126.1" "Low cancer specificity" "Detected in all" "Adipose visceral - Neutrophils, Liver - Hepatocytes, Lung - Neutrophils_2, Minor Salivary Gland - Smooth muscle cells, Pituitary gland - Lactotropes, Prostate - Prostate basal glandular cells, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011500, HPA031321" Uncertain "Secreted to blood" Receptor NA NA 8500 "Cluster 21: Neutrophils - Unknown function" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 67 "CAB011500: , HPA031321: " "unprognostic (1.77e-2)" "unprognostic (1.48e-1)" "unprognostic (4.43e-2)" "unprognostic (2.36e-1)" "unprognostic (1.24e-1)" "unprognostic (2.25e-1)" "unprognostic (3.86e-1)" "unprognostic (7.38e-2)" "unprognostic (4.04e-2)" "unprognostic (4.88e-2)" "validated prognostic favorable (1.40e-9)" "validated prognostic favorable (1.72e-4)" "unprognostic (4.30e-2)" "unprognostic (2.20e-2)" "unprognostic (3.15e-3)" "unprognostic (1.78e-2)" "unprognostic (2.30e-1)" "unprognostic (6.53e-3)" "unprognostic (2.22e-3)" "unprognostic (2.61e-2)" "unprognostic (1.02e-2)" "unprognostic (2.06e-1)" "unprognostic (2.24e-1)" "unprognostic (1.44e-1)" "unprognostic (1.34e-2)" "unprognostic (2.36e-1)" "unprognostic (2.12e-1)" "unprognostic (4.61e-1)" "unprognostic (1.70e-1)" "unprognostic (4.96e-2)" "unprognostic (1.22e-2)" SORT1 "Gp95, NT3" ENSG00000134243 "Sortilin 1" Q99523 1 109309568-109397918 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Endocytosis, Osteogenesis, Transport" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 446.5;Neutrophil progenitors: 440.2;Neutrophils: 408.7;Oligodendrocytes: 612.1;Podocytes: 446.5;Thymic myoid cells: 407.9;Vascular smooth muscle cells: 375.1" "Cell type enhanced" "Detected in all" "oligodendrocyte: 865.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 9.2;non-classical monocyte: 10.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006889, CAB011498" Enhanced Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA 120000 "Cluster 25: Non-specific - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 58 "Golgi apparatus, Cytosol" "Plasma membrane" "CAB011498: , HPA006889: " "unprognostic (1.92e-1)" "unprognostic (5.29e-2)" "unprognostic (1.03e-2)" "unprognostic (3.61e-1)" "potential prognostic favorable (2.02e-5)" "unprognostic (5.63e-2)" "unprognostic (2.17e-1)" "unprognostic (2.51e-2)" "unprognostic (1.75e-1)" "unprognostic (1.31e-3)" "validated prognostic favorable (2.94e-4)" "validated prognostic favorable (2.80e-4)" "unprognostic (4.33e-2)" "unprognostic (1.99e-3)" "unprognostic (8.20e-2)" "unprognostic (1.21e-2)" "unprognostic (4.21e-2)" "unprognostic (2.50e-1)" "unprognostic (2.09e-1)" "unprognostic (2.51e-1)" "unprognostic (9.90e-2)" "unprognostic (9.34e-2)" "unprognostic (4.51e-2)" "unprognostic (7.37e-2)" "unprognostic (3.81e-3)" "unprognostic (1.41e-1)" "unprognostic (3.03e-2)" "unprognostic (5.14e-2)" "unprognostic (7.09e-2)" "unprognostic (1.46e-1)" "unprognostic (9.26e-2)" SOS1 "GF1, GINGF, HGF" ENSG00000115904 "SOS Ras/Rac guanine nucleotide exchange factor 1" Q07889 2 38962206-39124345 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Megakaryocyte progenitors: 1356.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005396 Uncertain Approved Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 49: HMC-1 - Innate immune response" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 54 Cytosol "CAB005396: " "unprognostic (1.59e-2)" "unprognostic (1.46e-1)" "unprognostic (1.24e-1)" "unprognostic (1.77e-2)" "unprognostic (1.79e-1)" "unprognostic (2.61e-3)" "unprognostic (1.52e-1)" "unprognostic (1.93e-1)" "unprognostic (9.95e-2)" "unprognostic (1.27e-3)" "potential prognostic favorable (4.63e-6)" "unprognostic (4.81e-3)" "unprognostic (4.29e-2)" "unprognostic (5.62e-3)" "unprognostic (1.16e-1)" "unprognostic (1.69e-1)" "unprognostic (4.40e-2)" "unprognostic (1.01e-1)" "unprognostic (1.88e-1)" "unprognostic (1.88e-1)" "unprognostic (9.92e-2)" "unprognostic (7.01e-3)" "unprognostic (2.29e-2)" "unprognostic (1.44e-2)" "potential prognostic favorable (9.90e-4)" "unprognostic (7.52e-2)" "unprognostic (2.64e-1)" "unprognostic (6.31e-2)" "unprognostic (7.60e-2)" "unprognostic (2.47e-2)" "unprognostic (2.35e-2)" SOS2 ENSG00000100485 "SOS Ras/Rho guanine nucleotide exchange factor 2" Q07890 14 50117130-50231578 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 882.5;Neutrophils: 1844.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 8.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004577, HPA047368, HPA052689" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 18 "Nucleoplasm, Vesicles" "CAB004577: , HPA047368: , HPA052689: " "unprognostic (8.55e-2)" "unprognostic (4.08e-2)" "unprognostic (5.30e-2)" "unprognostic (7.77e-2)" "unprognostic (1.38e-1)" "unprognostic (2.72e-1)" "unprognostic (4.93e-2)" "unprognostic (5.61e-3)" "unprognostic (8.80e-2)" "unprognostic (2.55e-3)" "validated prognostic favorable (4.01e-8)" "validated prognostic favorable (2.05e-4)" "unprognostic (5.47e-2)" "unprognostic (3.51e-2)" "unprognostic (2.29e-1)" "unprognostic (3.37e-1)" "unprognostic (1.42e-1)" "unprognostic (1.60e-1)" "unprognostic (2.41e-3)" "unprognostic (4.25e-1)" "unprognostic (4.28e-2)" "unprognostic (9.41e-2)" "unprognostic (1.99e-2)" "unprognostic (1.20e-1)" "unprognostic (1.96e-2)" "unprognostic (1.35e-2)" "unprognostic (2.07e-1)" "unprognostic (3.61e-2)" "unprognostic (1.48e-1)" "unprognostic (3.26e-2)" "unprognostic (3.54e-2)" SOST "DAND6, VBCH" ENSG00000167941 Sclerostin Q9BQB4 17 43753738-43758791 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted secreted proteins" "Wnt signaling pathway" Heparin-binding "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "blood vessel: 66.6" "Cell type enhanced" "Detected in some" "Cholangiocytes: 2.0;Innate lymphoid cells: 6.1;Podocytes: 11.1;Vascular endothelial cells: 2.2;Vascular smooth muscle cells: 1.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Bladder Urothelial Carcinoma (TCGA): 7.8;Lung Squamous Cell Carcinoma (TCGA): 17.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 12.3;Rhabdoid: 19.6" "Group enriched" "Detected in some" 11 "basal ganglia: 1.7;cerebellum: 1.0" "Not detected" "Not detected" "Secreted to extracellular matrix" Other NA NA 280000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 7: Liver cancer - Metabolism" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 17 "unprognostic (1.65e-1)" "unprognostic (2.39e-1)" "unprognostic (4.78e-2)" "unprognostic (3.97e-1)" SOSTDC1 "DAND7, DKFZp564D206, USAG1" ENSG00000171243 "Sclerostin domain containing 1" Q6X4U4 7 16461481-16530580 "Predicted secreted proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "choroid plexus: 233.3" "Cell type enhanced" "Detected in some" "Breast lactating cells: 1.9;Early spermatids: 21.6;Late primary spermatocytes: 9.1;Loop of henle epithelial cells: 3.7;Proximal tubule cells: 4.1" "Low cell type specificity" "Detected in single" "Cancer enriched" "Detected in many" 7 "Kidney Renal Papillary Cell Carcinoma (TCGA): 169.4" "Region enriched" "Detected in all" 27 "choroid plexus: 247.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast myoepithelial cells, Minor Salivary Gland - Minor salivary glandular cells, Skin - Outer root sheath cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Group enriched" "Detected in many" 5 "basal ganglia: 9.2;hippocampal formation: 18.4;pons and medulla: 15.1;thalamus: 11.9" "Low region specificity" "Detected in many" HPA042856 Uncertain "Nucleoli,Nucleoli rim,Golgi apparatus,Vesicles" "Secreted to extracellular matrix" Other NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 4 "Golgi apparatus" "Nucleoli, Nucleoli rim, Vesicles" "HPA042856: " "unprognostic (1.19e-1)" "unprognostic (3.42e-2)" "unprognostic (1.10e-2)" "unprognostic (7.44e-2)" "unprognostic (1.13e-1)" "unprognostic (1.73e-1)" "unprognostic (3.45e-2)" "unprognostic (3.27e-3)" "unprognostic (5.24e-2)" "unprognostic (1.42e-2)" "potential prognostic favorable (1.13e-5)" "unprognostic (7.31e-3)" "unprognostic (1.91e-2)" "unprognostic (1.53e-2)" "unprognostic (1.07e-2)" "unprognostic (9.98e-2)" "potential prognostic favorable (8.59e-4)" "unprognostic (3.78e-3)" "unprognostic (2.87e-1)" "unprognostic (2.48e-1)" "potential prognostic unfavorable (5.23e-4)" "unprognostic (2.57e-1)" "unprognostic (6.74e-2)" "unprognostic (2.02e-2)" "unprognostic (8.34e-2)" "unprognostic (5.14e-2)" "unprognostic (1.61e-1)" "unprognostic (1.08e-1)" SOWAHA ANKRD43 ENSG00000198944 "Sosondowah ankyrin repeat domain family member A" Q2M3V2 5 132813302-132816786 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 15 "brain: 142.5;intestine: 37.0" "Cell type enhanced" "Detected in many" "Colonocytes: 27.7;Enteric transient amplifying cells: 21.1;Enterocytes: 98.0;Epididymal clear cells: 44.9;Gastric chief cells: 19.7;Mucous neck cells: 21.7;Müller glia: 25.9;Neuroendocrine cells: 22.2;Parietal cells: 42.4;Retinal horizontal cells: 90.2;Tuft cells: 23.1" "Cell type enhanced" "Detected in many" "eccentric medium spiny neuron: 26.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 3.9" "Adrenal gland - Adrenal medulla cells, Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "basal ganglia: 80.2" HPA064621 Approved NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 1: Enterocytes - Absorption and Digestion" 1 "HPA064621: " "unprognostic (1.68e-3)" "unprognostic (1.14e-1)" "unprognostic (1.31e-3)" "unprognostic (1.76e-2)" "unprognostic (1.89e-1)" "unprognostic (1.02e-1)" "unprognostic (4.79e-3)" "unprognostic (2.24e-1)" "unprognostic (2.87e-1)" "unprognostic (1.52e-3)" "unprognostic (7.95e-2)" "unprognostic (3.50e-2)" "potential prognostic favorable (2.22e-4)" "unprognostic (3.60e-2)" "unprognostic (2.97e-1)" "unprognostic (9.09e-3)" "unprognostic (7.10e-3)" "unprognostic (3.79e-1)" "unprognostic (1.08e-2)" SOWAHB ANKRD56 ENSG00000186212 "Sosondowah ankyrin repeat domain family member B" A6NEL2 4 76894152-76898144 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 17.9" "Cell type enhanced" "Detected in many" "Colonocytes: 14.1;Endometrial ciliated cells: 9.7;Enterocytes: 9.9;Esophageal apical cells: 29.2;Esophageal suprabasal cells: 11.4;Hepatocytes: 23.4;Urothelial cells: 49.1" "Cell type enhanced" "Detected in some" "deep-layer near-projecting: 5.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 8.9" "Breast - Breast glandular cells, Colon - Colon enterocytes, Liver - Hepatocytes, Lung - Alveolar cells type 2, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA036809, HPA036810" Approved Approved "Nucleoli fibrillar center" NA NA "Cluster 76: Non-specific - Metabolism" "Cluster 53: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 69: Urothelial cells - Basic cellular functions" 2 "Nucleoli fibrillar center" "HPA036809: , HPA036810: " "unprognostic (1.04e-2)" "unprognostic (2.57e-1)" "unprognostic (1.31e-1)" "unprognostic (3.37e-2)" "unprognostic (1.89e-2)" "unprognostic (8.77e-3)" "unprognostic (2.40e-1)" "validated prognostic favorable (5.88e-15)" "validated prognostic favorable (8.18e-5)" "unprognostic (2.79e-2)" "unprognostic (1.94e-2)" "unprognostic (4.41e-2)" "unprognostic (7.65e-2)" "unprognostic (7.13e-2)" "unprognostic (1.31e-1)" "unprognostic (4.19e-1)" "unprognostic (3.33e-1)" "unprognostic (2.48e-3)" "unprognostic (1.02e-1)" "unprognostic (2.45e-1)" "unprognostic (1.08e-2)" "unprognostic (5.12e-2)" "unprognostic (2.13e-1)" "unprognostic (1.42e-1)" "unprognostic (1.67e-2)" SOWAHC "ANKRD57, C2orf26, FLJ21870" ENSG00000198142 "Sosondowah ankyrin repeat domain family member C" Q53LP3 2 109614364-109618990 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 147.8;Esophageal apical cells: 386.1;Esophageal basal cells: 101.6;Esophageal suprabasal cells: 149.1;Ocular epithelial cells: 94.4;Suprabasal keratinocytes: 182.1;Urothelial cells: 313.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Minor salivary gland basal cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" HPA056131 Enhanced Approved Cytosol No No "Cluster 11: Esophagus - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 69: Urothelial cells - Basic cellular functions" 12 Cytosol "HPA056131: " "unprognostic (1.25e-1)" "unprognostic (3.20e-2)" "unprognostic (9.97e-3)" "unprognostic (2.36e-1)" "unprognostic (5.33e-1)" "unprognostic (1.55e-1)" "unprognostic (1.12e-2)" "unprognostic (1.85e-2)" "unprognostic (1.91e-1)" "potential prognostic favorable (3.08e-9)" "unprognostic (1.41e-3)" "unprognostic (2.35e-1)" "unprognostic (3.42e-3)" "potential prognostic unfavorable (3.86e-6)" "unprognostic (3.12e-2)" "unprognostic (1.86e-1)" "unprognostic (2.42e-1)" "unprognostic (1.05e-1)" "unprognostic (4.14e-2)" "unprognostic (1.92e-3)" "unprognostic (6.22e-3)" "unprognostic (5.68e-2)" "unprognostic (1.65e-2)" "unprognostic (3.75e-2)" "unprognostic (2.28e-2)" "unprognostic (1.27e-1)" "unprognostic (2.08e-1)" "unprognostic (8.53e-2)" "unprognostic (1.41e-2)" SOWAHD ANKRD58 ENSG00000187808 "Sosondowah ankyrin repeat domain family member D" A6NJG2 X 119758588-119760202 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 3.8;lymphoid tissue: 6.7;testis: 4.8" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 7.5;Enterocytes: 8.5;Extravillous trophoblasts: 60.8;Hofbauer cells: 20.6;Kupffer cells: 6.1;Microglia: 5.9;Migrating cytotrophoblasts: 11.8;Monocyte progenitors: 6.8;Neutrophil progenitors: 6.7;Parietal cells: 8.8;Syncytiotrophoblasts: 9.5" "Cell type enriched" "Detected in some" 5 "central nervous system macrophage: 6.5" "Cancer enriched" "Detected in many" 8 "Testicular Germ Cell Tumor (TCGA): 13.1" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "naive B-cell: 11.8" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Leukemia: 5.4" "Adipose subcutaneous - Macrophages, Lung - Macrophages, Stomach - Parietal cells, Testis - Sertoli cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA065955 Uncertain NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" "HPA065955: " "unprognostic (1.22e-1)" "unprognostic (1.80e-2)" "unprognostic (1.66e-1)" "unprognostic (3.91e-3)" "unprognostic (2.13e-1)" "unprognostic (7.25e-2)" "unprognostic (1.27e-2)" "potential prognostic unfavorable (5.71e-4)" "unprognostic (3.03e-2)" "unprognostic (3.10e-1)" "unprognostic (1.73e-2)" "unprognostic (1.46e-1)" "unprognostic (7.62e-2)" "unprognostic (1.83e-1)" "unprognostic (2.47e-1)" "unprognostic (1.29e-1)" "unprognostic (9.18e-2)" SOX1 ENSG00000182968 "SRY-box transcription factor 1" O00570 13 112067149-112071706 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "brain: 3.9" "Cell type enhanced" "Detected in single" "Bergmann glia: 1.1" "Cell type enriched" "Detected in single" 5 "Bergmann glia: 1.8" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 2.6;Skin Cutaneous Melanoma (TCGA): 2.0" "Region enhanced" "Detected in all" "hypothalamus: 32.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "Bone cancer: 5.5;lung cancer: 5.5" "Colon - Enteric glia cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 28: Astrocytes - Homeostasis & neuron support" 1 "unprognostic (8.12e-2)" "unprognostic (1.49e-2)" "unprognostic (3.69e-1)" "unprognostic (1.31e-1)" "unprognostic (8.07e-2)" SOX10 "DOM, SOX-10, WS2E, WS4" ENSG00000100146 "SRY-box transcription factor 10" P56693 22 37970686-37987422 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Deafness, Disease variant, Hirschsprung disease, Kallmann syndrome, Waardenburg syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 151.8;salivary gland: 105.2" "Group enriched" "Detected in many" 6 "Breast lactating cells: 86.8;Breast myoepithelial cells: 56.8;Breast secretory cells: 63.9;Lacrimal acinar cells: 96.0;Melanocytes: 167.7;Oligodendrocyte progenitor cells: 130.3;Oligodendrocytes: 134.7;Salivary acinar cells: 76.1;Salivary myoepithelial cells: 50.1;Schwann cells: 183.6" "Group enriched" "Detected in many" 59 "committed oligodendrocyte precursor: 230.6;oligodendrocyte: 122.4;oligodendrocyte precursor cell: 143.8" "Cancer enriched" "Detected in many" 9 "Skin Cutaneous Melanoma (TCGA): 542.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 16 "skin cancer: 313.1" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Skin - Eccrine sweat gland cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003171, HPA068898" Enhanced Supported Nucleoplasm Yes NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 61: Schwann cells & Melanocytes - Mixed function" 20 Nucleoplasm "CAB003171: , HPA068898: " "unprognostic (3.46e-3)" "unprognostic (2.43e-1)" "unprognostic (1.47e-1)" "unprognostic (9.51e-2)" "unprognostic (1.14e-1)" "unprognostic (8.32e-2)" "unprognostic (2.90e-1)" "unprognostic (1.73e-2)" "unprognostic (7.51e-2)" "unprognostic (1.68e-1)" "unprognostic (2.61e-2)" "unprognostic (2.39e-1)" SOX11 ENSG00000176887 "SRY-box transcription factor 11" P35716 2 5692384-5701385 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 2.7" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 4.6;Brain inhibitory neurons: 15.4;Breast myoepithelial cells: 10.3;Breast secretory cells: 11.7;Ependymal cells: 7.3;Myosatellite cells: 4.7;Oligodendrocyte progenitor cells: 15.6;Other brain neurons: 18.5;Retinal amacrine cells: 4.6;Retinal ganglion cells: 3.9" "Cell type enhanced" "Detected in many" "midbrain-derived inhibitory: 40.2" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 13.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Bone cancer: 12.9;Neuroblastoma: 48.4" "Skeletal muscle - Fibroblasts, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA000448, HPA000536, CAB056152, CAB056153" Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 98: Neurons - Neurotransmission & signaling" 1 Nucleoplasm "Plasma membrane" "CAB056152: , CAB056153: , HPA000448: , HPA000536: " "unprognostic (2.81e-2)" "unprognostic (5.59e-2)" "unprognostic (2.83e-1)" "unprognostic (8.61e-3)" "unprognostic (7.25e-3)" "unprognostic (1.39e-1)" "unprognostic (2.28e-2)" "unprognostic (3.75e-1)" "unprognostic (1.87e-1)" "unprognostic (1.70e-1)" "unprognostic (1.05e-2)" SOX12 SOX22 ENSG00000177732 "SRY-box transcription factor 12" O15370 20 325552-330224 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Retinal bipolar cells: 33.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055052, HPA061627" Enhanced Nucleoplasm No No "Cluster 64: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" Nucleoplasm "HPA055052: , HPA061627: " "unprognostic (6.61e-2)" "unprognostic (1.08e-1)" "unprognostic (4.00e-1)" "unprognostic (1.62e-2)" "unprognostic (2.02e-3)" "unprognostic (1.12e-2)" "unprognostic (1.88e-3)" "unprognostic (5.08e-2)" "unprognostic (1.76e-1)" "unprognostic (1.90e-1)" "potential prognostic unfavorable (8.82e-8)" "unprognostic (1.03e-2)" "unprognostic (7.33e-2)" "validated prognostic unfavorable (2.02e-5)" "validated prognostic unfavorable (3.70e-6)" "unprognostic (6.08e-2)" "unprognostic (2.95e-1)" "unprognostic (9.90e-2)" "unprognostic (4.13e-3)" "unprognostic (1.60e-1)" "unprognostic (1.05e-1)" "unprognostic (5.38e-3)" "unprognostic (4.20e-2)" "unprognostic (2.84e-2)" "unprognostic (1.71e-1)" "unprognostic (5.91e-2)" "unprognostic (7.95e-2)" "unprognostic (1.61e-2)" "unprognostic (2.18e-1)" "unprognostic (2.48e-2)" "unprognostic (6.03e-2)" SOX13 "ICA12, MGC117216, Sox-13" ENSG00000143842 "SRY-box transcription factor 13" Q9UN79 1 204073115-204127743 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial luminal cells: 85.0;Mast cells: 84.6;Oligodendrocyte progenitor cells: 98.4;Vascular smooth muscle cells: 80.7" "Cell type enhanced" "Detected in many" "endothelial cell: 119.9;oligodendrocyte precursor cell: 116.6;vascular associated smooth muscle cell: 97.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 1.6" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051790, HPA054843" Enhanced Nucleoplasm NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 19: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 105: Non-specific - Mixed function" 13 Nucleoplasm "HPA051790: , HPA054843: " "unprognostic (3.36e-2)" "unprognostic (4.15e-3)" "unprognostic (2.27e-1)" "unprognostic (2.03e-1)" "unprognostic (6.09e-2)" "potential prognostic unfavorable (9.21e-4)" "unprognostic (3.03e-1)" "potential prognostic favorable (2.80e-4)" "unprognostic (2.17e-2)" "unprognostic (3.08e-2)" "potential prognostic favorable (5.57e-8)" "unprognostic (1.82e-3)" "unprognostic (1.33e-1)" "unprognostic (3.42e-2)" "unprognostic (2.26e-2)" "unprognostic (7.31e-2)" "unprognostic (8.23e-2)" "unprognostic (5.06e-2)" "unprognostic (8.54e-3)" "unprognostic (2.83e-1)" "unprognostic (3.58e-1)" "unprognostic (1.32e-2)" "unprognostic (4.92e-2)" "unprognostic (2.68e-1)" "unprognostic (6.15e-2)" "unprognostic (3.57e-1)" "unprognostic (3.21e-1)" "unprognostic (7.88e-2)" "unprognostic (5.63e-2)" "unprognostic (1.65e-2)" "unprognostic (2.13e-2)" SOX14 SOX28 ENSG00000168875 "SRY-box transcription factor 14" O95416 3 137764315-137766334 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.7;placenta: 1.6" "Cell type enhanced" "Detected in some" "Brain inhibitory neurons: 9.7;Cytotrophoblasts: 25.2;Gastric progenitor cells: 2.6;Migrating cytotrophoblasts: 6.1;Parietal cells: 1.8;Syncytiotrophoblasts: 3.2" "Cell type enriched" "Detected in some" 28 "midbrain-derived inhibitory: 60.0" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 3.0;Prostate Adenocarcinoma (TCGA): 4.1" "Region enhanced" "Detected in many" "hypothalamus: 25.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 1.1;Rhabdoid: 1.3" "Prostate - Prostate glandular cells" "Group enriched" "Detected in some" 6 "hypothalamus: 1.7;midbrain: 4.9" "Group enriched" "Detected in some" 6 "midbrain: 9.3;pons: 5.8;thalamus: 15.5" NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 14 "unprognostic (1.31e-1)" "unprognostic (2.36e-1)" "unprognostic (1.28e-1)" "unprognostic (4.51e-1)" "unprognostic (1.79e-1)" "unprognostic (8.70e-3)" "unprognostic (1.83e-1)" "potential prognostic unfavorable (6.18e-4)" "unprognostic (1.36e-3)" SOX15 "SOX20, SOX26, SOX27" ENSG00000129194 "SRY-box transcription factor 15" O60248 17 7588178-7590094 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 85.9;skin 1: 48.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 188.2;Epididymal basal cells: 58.3;Esophageal apical cells: 238.9;Esophageal basal cells: 203.3;Esophageal suprabasal cells: 205.6;Ocular epithelial cells: 193.6;Suprabasal keratinocytes: 163.2" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 77.8;Testicular Germ Cell Tumor (TCGA): 129.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 6.7;non-classical monocyte: 10.6" "Lineage enriched" "Detected in many" 5 "monocytes: 10.6" "Cancer enhanced" "Detected in all" "cervical cancer: 73.6;Esophageal cancer: 53.2;head and neck cancer: 82.2" "Minor Salivary Gland - Minor salivary gland basal cells, Skin - Keratinocyte (other), Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Not detected" "Not detected" "HPA067196, HPA074049" Enhanced Approved Nucleoplasm,Nucleoli,Vesicles Yes NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 26: Keratinocytes - Keratinization" 26 Nucleoplasm "Nucleoli, Vesicles" "HPA067196: , HPA074049: " "unprognostic (9.76e-2)" "unprognostic (2.02e-2)" "unprognostic (4.65e-3)" "unprognostic (3.57e-1)" "unprognostic (2.75e-2)" "unprognostic (4.44e-2)" "unprognostic (3.03e-1)" "unprognostic (2.07e-1)" "unprognostic (6.67e-2)" "unprognostic (6.75e-2)" "unprognostic (1.61e-3)" "unprognostic (1.33e-1)" "unprognostic (1.76e-2)" "unprognostic (5.59e-2)" "unprognostic (5.93e-2)" "potential prognostic favorable (8.00e-4)" "unprognostic (9.45e-2)" "unprognostic (2.43e-1)" "unprognostic (1.41e-1)" "unprognostic (1.25e-1)" "unprognostic (3.67e-1)" "unprognostic (1.14e-1)" "unprognostic (1.77e-1)" "unprognostic (3.51e-3)" "unprognostic (6.29e-2)" SOX17 ENSG00000164736 "SRY-box transcription factor 17" Q9H6I2 8 54457935-54460892 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 46.8" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 256.3;Endometrial glandular cells: 470.9;Endometrial luminal cells: 604.9;Endometrial secretory cells: 282.9;Fallopian secretory cells: 113.7;Fallopian tube ciliated cells: 137.0;Vascular endothelial cells: 172.0" "Cell type enriched" "Detected in some" 5 "endothelial cell: 52.6" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 125.8;Uterine Corpus Endometrial Carcinoma (TCGA): 160.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 14 "liver cancer: 9.6;ovarian cancer: 38.3;Rhabdoid: 33.2;Uterine cancer: 37.0" "Breast - Endothelial cells, Colon - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025594, HPA058949, HPA068399" Enhanced Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 3 Nucleoplasm "Nuclear membrane" "CAB025594: , HPA058949: , HPA068399: " "unprognostic (3.50e-1)" "unprognostic (2.17e-1)" "unprognostic (2.06e-1)" "unprognostic (1.05e-2)" "unprognostic (1.02e-1)" "unprognostic (7.52e-2)" "unprognostic (2.09e-2)" "unprognostic (1.38e-2)" "validated prognostic favorable (6.22e-6)" "validated prognostic favorable (5.39e-4)" "unprognostic (8.71e-3)" "unprognostic (4.23e-3)" "unprognostic (2.03e-1)" "unprognostic (6.19e-2)" "unprognostic (1.22e-1)" "unprognostic (1.15e-2)" "unprognostic (1.71e-1)" "unprognostic (1.37e-1)" "unprognostic (1.22e-1)" "unprognostic (7.35e-3)" "unprognostic (1.05e-1)" "unprognostic (3.73e-1)" "unprognostic (2.47e-3)" SOX18 ENSG00000203883 "SRY-box transcription factor 18" P35713 20 64047582-64049639 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 77.1" "Group enriched" "Detected in some" 14 "Late primary spermatocytes: 78.0;Lymphatic endothelial cells: 120.4;Vascular endothelial cells: 268.4" "Cell type enriched" "Detected in some" 10 "endothelial cell: 248.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 10.9" "Breast - Endothelial cells, Colon - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073703 Approved Nucleoplasm NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 38: Non-specific - Transcription" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 1 Nucleoplasm "HPA073703: " "unprognostic (5.80e-2)" "unprognostic (2.27e-1)" "unprognostic (3.10e-2)" "unprognostic (2.68e-1)" "unprognostic (2.34e-2)" "unprognostic (1.94e-1)" "unprognostic (2.36e-2)" "unprognostic (1.05e-1)" "unprognostic (2.30e-2)" "unprognostic (1.26e-2)" "unprognostic (3.22e-3)" "unprognostic (1.90e-3)" "potential prognostic unfavorable (6.23e-4)" "unprognostic (7.27e-2)" "unprognostic (9.97e-3)" "unprognostic (4.48e-2)" "unprognostic (8.78e-3)" "unprognostic (1.02e-1)" "unprognostic (1.44e-1)" "unprognostic (1.73e-3)" "unprognostic (2.10e-1)" "unprognostic (9.36e-2)" "unprognostic (1.45e-3)" "unprognostic (2.48e-1)" "unprognostic (2.06e-1)" "unprognostic (9.69e-3)" "unprognostic (2.07e-1)" "unprognostic (1.41e-1)" "unprognostic (5.24e-2)" SOX2 ENSG00000181449 "SRY-box transcription factor 2" P48431 3 181711925-181714436 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 71.9;esophagus: 22.9" "Cell type enhanced" "Detected in some" "Astrocytes: 2.1;Bergmann glia: 1.6;Gastric chief cells: 1.1;Podocytes: 4.1;Respiratory deuterosomal cells: 1.0;Schwann cells: 2.8" "Cell type enhanced" "Detected in some" "astrocyte: 2.2;Bergmann glia: 2.3" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 224.8;Lung Squamous Cell Carcinoma (TCGA): 120.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 74.9" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Lung - Respiratory ciliated cells, Pituitary gland - Undifferentiated cells (Pituitary gland)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045725, HPA062851, HPA071379, CAB079745" Enhanced Supported Enhanced Nucleoplasm NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 61: Schwann cells & Melanocytes - Mixed function" 214 Nucleoplasm "CAB079745: , HPA045725: , HPA062851: , HPA071379: " "unprognostic (2.57e-1)" "unprognostic (1.41e-2)" "unprognostic (1.42e-1)" "unprognostic (1.57e-2)" "unprognostic (1.86e-1)" "unprognostic (2.64e-2)" "unprognostic (5.80e-2)" "unprognostic (7.93e-3)" "unprognostic (1.04e-1)" "unprognostic (9.82e-3)" "unprognostic (8.30e-2)" "unprognostic (1.74e-3)" "unprognostic (6.83e-3)" "unprognostic (2.55e-3)" "unprognostic (3.03e-3)" "unprognostic (5.42e-2)" "unprognostic (5.49e-2)" "unprognostic (5.95e-2)" "unprognostic (1.56e-2)" "unprognostic (9.14e-2)" "unprognostic (8.52e-2)" "unprognostic (2.72e-1)" "unprognostic (1.77e-2)" SOX21 SOX25 ENSG00000125285 "SRY-box transcription factor 21" Q9Y651 13 94709622-94712545 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 12.1;esophagus: 9.6;skin 1: 15.0;stomach 1: 33.1" "Cell type enhanced" "Detected in some" "Astrocytes: 15.7;Conjunctival goblet cells: 20.4;Ependymal cells: 14.4;Esophageal apical cells: 15.6;Esophageal suprabasal cells: 16.3;Foveolar cells: 102.0;Gastric chief cells: 16.4;Mucous neck cells: 29.4;Oligodendrocyte progenitor cells: 32.0;Respiratory basal cells: 14.9;Respiratory deuterosomal cells: 28.0;Respiratory secretory cells: 31.4" "Group enriched" "Detected in some" 12 "astrocyte: 14.1;Bergmann glia: 14.4;committed oligodendrocyte precursor: 12.2;ependymal cell: 15.9;oligodendrocyte precursor cell: 35.0" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 20.3;Lung Squamous Cell Carcinoma (TCGA): 12.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 13.8" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048337, HPA064084" Approved Approved Nucleoplasm NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 72: Neuronal - Signal transduction" "Cluster 68: Foveolar cells - Mucosal defense" 1 Nucleoplasm "HPA048337: , HPA064084: " "unprognostic (4.14e-1)" "unprognostic (1.79e-3)" "unprognostic (2.44e-3)" "unprognostic (3.29e-1)" "unprognostic (1.21e-2)" "unprognostic (7.00e-2)" "unprognostic (1.43e-1)" "unprognostic (2.54e-2)" "unprognostic (7.18e-3)" "unprognostic (1.34e-2)" "unprognostic (3.05e-2)" "unprognostic (4.39e-2)" "unprognostic (5.84e-1)" "unprognostic (6.30e-2)" SOX3 PHP ENSG00000134595 "SRY-box transcription factor 3" P41225 X 140502985-140505069 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.3;fallopian tube: 8.7;testis: 2.2" "Group enriched" "Detected in some" 4 "Fallopian secretory cells: 38.4;Fallopian tube ciliated cells: 35.2;Oocytes: 18.4" "Cell type enriched" "Detected in some" 9 "oligodendrocyte precursor cell: 10.5" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 3.3" "Region enriched" "Detected in many" 5 "hypothalamus: 9.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Brain cancer: 8.8;testis cancer: 3.1" "Pituitary gland - Gonadotropes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA054720, HPA075003" Enhanced Nucleoplasm NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 72: Neuronal - Signal transduction" "Cluster 11: Muller glia cells - Retinal homeostasis" 3 Nucleoplasm "HPA054720: , HPA075003: " "unprognostic (2.31e-1)" "unprognostic (5.08e-2)" "potential prognostic favorable (3.32e-4)" "unprognostic (1.06e-1)" "unprognostic (2.42e-1)" SOX30 ENSG00000039600 "SRY-box transcription factor 30" O94993 5 157625679-157671480 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 85 "testis: 76.2" "Cell type enhanced" "Detected in some" "Early primary spermatocytes: 25.7;Early spermatids: 431.9;Epididymal efferent duct ciliated cells: 28.5;Late primary spermatocytes: 180.8;Late spermatids: 94.9" "Cell type enhanced" "Detected in many" "ependymal cell: 5.2" "Cancer enhanced" "Detected in single" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 2.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "colorectal cancer: 1.5" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA006159, CAB009382" Enhanced Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 6: Testis - Spermatogenesis" "Cluster 70: DU4475 - Unknown function" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 4 "Nucleoplasm, Vesicles" Cytosol "CAB009382: , HPA006159: " "unprognostic (8.77e-2)" "unprognostic (1.22e-1)" "unprognostic (2.75e-2)" SOX4 ENSG00000124766 "SRY-box transcription factor 4" Q06945 6 21593751-21598619 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 68.4;ovary: 66.7" "Cell type enhanced" "Detected in many" "Megakaryocyte-Erythroid progenitors: 780.2;Thymocytes: 778.3" "Group enriched" "Detected in all" 4 "committed oligodendrocyte precursor: 327.4;midbrain-derived inhibitory: 98.6;oligodendrocyte precursor cell: 108.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 45.8" "Group enriched" "Detected in all" 5 "dendritic cells: 45.8;granulocytes: 33.4;monocytes: 22.1" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Region enhanced" "Detected in all" "olfactory bulb: 54.2" "Low region specificity" "Detected in all" HPA029901 Approved Supported Nucleoplasm,Mitochondria NA Yes "Cluster 10: Non-specific - Membrane trafficking" "Cluster 61: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 59: Leukemia - T-cell receptor" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 8 Nucleoplasm Mitochondria "HPA029901: " "unprognostic (3.79e-2)" "unprognostic (3.27e-2)" "unprognostic (4.63e-2)" "unprognostic (4.75e-2)" "unprognostic (3.96e-2)" "unprognostic (2.33e-1)" "unprognostic (3.01e-2)" "unprognostic (2.89e-3)" "unprognostic (5.08e-2)" "unprognostic (2.66e-1)" "unprognostic (5.86e-3)" "potential prognostic favorable (4.77e-6)" "unprognostic (3.82e-2)" "potential prognostic unfavorable (9.41e-6)" "unprognostic (2.53e-3)" "unprognostic (2.19e-2)" "unprognostic (3.68e-3)" "unprognostic (1.19e-1)" "unprognostic (1.26e-2)" "unprognostic (1.06e-1)" "unprognostic (1.07e-3)" "unprognostic (1.28e-2)" "unprognostic (3.56e-2)" "unprognostic (7.30e-2)" "unprognostic (2.47e-2)" "unprognostic (2.40e-1)" "unprognostic (1.45e-3)" "unprognostic (4.44e-2)" "unprognostic (2.97e-1)" "unprognostic (2.08e-1)" "unprognostic (1.67e-1)" SOX5 "L-SOX5, MGC35153" ENSG00000134532 "SRY-box transcription factor 5" P35711 12 23529504-24562544 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding" "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 29.2" "Cell type enhanced" "Detected in many" "Adipocytes: 4038.1;Astrocytes: 2417.9;Bergmann glia: 2542.8;Endometrial stromal cells: 2054.4;Ependymal cells: 1989.1;Fibro-adipogenic progenitors: 1444.9;Melanocytes: 1416.3;Oligodendrocyte progenitor cells: 2091.0;Pituicytes/FSCs: 1319.5;Renal collecting duct principal cells: 1356.4;Retinal ganglion cells: 1437.0;Vascular smooth muscle cells: 1533.9" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 8.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory B-cell: 1.4;naive B-cell: 1.3" "Lineage enriched" "Detected in single" 4 "B-cells: 1.4" "Cancer enhanced" "Detected in many" "skin cancer: 14.5" "Kidney - Fibroblasts, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060499 Supported Nucleoplasm NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 47: Testis - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 69: Skin cancer - ECM organization" "Cluster 89: Adipocytes - Lipid metabolism" 34 Nucleoplasm "HPA060499: " "unprognostic (1.12e-2)" "unprognostic (1.61e-1)" "unprognostic (3.52e-2)" "unprognostic (4.31e-1)" "unprognostic (2.73e-1)" "unprognostic (1.35e-1)" "unprognostic (3.64e-2)" "unprognostic (1.26e-3)" "unprognostic (3.08e-2)" "unprognostic (2.18e-1)" "unprognostic (2.22e-1)" "unprognostic (1.95e-3)" "unprognostic (2.70e-3)" "unprognostic (1.90e-1)" "unprognostic (4.03e-1)" "unprognostic (4.13e-2)" "unprognostic (1.09e-2)" "unprognostic (6.96e-2)" "unprognostic (3.06e-2)" "unprognostic (1.84e-2)" "unprognostic (1.97e-1)" "unprognostic (3.24e-1)" SOX6 ENSG00000110693 "SRY-box transcription factor 6" P35712 11 15966449-16739591 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Autism spectrum disorder, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.3" "Cell type enhanced" "Detected in many" "Corticotrophs: 1892.0;Ependymal cells: 1639.0;Lactotrophs: 969.7;Mesothelial cells: 1086.7;Myonuclei: 1739.9;Oligodendrocyte progenitor cells: 2702.9;Pituicytes/FSCs: 1003.7;Pituitary stem cells: 1024.4;Thymic myoid cells: 1040.1" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 4041.1;oligodendrocyte precursor cell: 3252.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 20 "neutrophil: 2.0" "Lineage enriched" "Detected in single" 20 "granulocytes: 2.0" "Cancer enhanced" "Detected in some" "Bone cancer: 10.3;skin cancer: 7.6" "Adipose visceral - Mesothelial cells, Colon - Enteric glia cells, Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001923, HPA003908" Enhanced Supported Nucleoplasm NA NA "Cluster 44: Bone marrow - Nuclear processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 20 Nucleoplasm "HPA001923: , HPA003908: " "unprognostic (8.87e-2)" "unprognostic (2.98e-1)" "unprognostic (5.14e-3)" "unprognostic (2.19e-3)" "unprognostic (2.24e-3)" "unprognostic (1.22e-2)" "unprognostic (2.49e-1)" "potential prognostic favorable (2.80e-9)" "unprognostic (1.75e-3)" "unprognostic (1.38e-2)" "unprognostic (6.36e-3)" "unprognostic (2.68e-1)" "unprognostic (1.24e-2)" "unprognostic (7.62e-3)" "unprognostic (1.01e-1)" "potential prognostic favorable (6.51e-5)" "unprognostic (6.92e-2)" "unprognostic (1.97e-1)" "unprognostic (1.72e-1)" "unprognostic (7.31e-2)" "unprognostic (3.23e-1)" "unprognostic (5.07e-2)" "unprognostic (7.08e-2)" "unprognostic (3.25e-2)" SOX7 ENSG00000171056 "SRY-box transcription factor 7" Q9BT81 8 10723768-10730511 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "vagina: 40.8" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 2.8;Brain inhibitory neurons: 3.3;Other brain neurons: 2.3;Papillary tip epithelial cells: 1.5;Renal collecting duct intercalated cells: 1.0;Vascular endothelial cells: 2.8" "Cell type enriched" "Detected in many" 8 "endothelial cell: 52.5" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 12.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "pancreatic cancer: 13.5" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Stomach - Endothelial cells, Thyroid gland - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA009065 Approved Approved "Nuclear speckles,Golgi apparatus" NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 104: Brain endothelial cells - Blood brain barrier" 4 "Nuclear speckles" "Golgi apparatus" "HPA009065: " "unprognostic (4.03e-2)" "unprognostic (3.88e-2)" "unprognostic (2.27e-1)" "unprognostic (2.90e-1)" "unprognostic (1.03e-1)" "unprognostic (1.20e-1)" "unprognostic (9.72e-2)" "unprognostic (1.94e-1)" "validated prognostic favorable (4.41e-4)" "validated prognostic favorable (1.00e-4)" "unprognostic (8.39e-2)" "unprognostic (8.30e-3)" "unprognostic (9.77e-2)" "unprognostic (2.56e-1)" "unprognostic (2.00e-1)" "unprognostic (5.71e-2)" "unprognostic (5.81e-3)" "unprognostic (2.32e-2)" "unprognostic (2.01e-1)" "unprognostic (1.97e-1)" "unprognostic (6.96e-3)" "unprognostic (1.31e-1)" "unprognostic (3.23e-3)" "unprognostic (7.28e-3)" "unprognostic (1.84e-1)" "potential prognostic unfavorable (2.07e-4)" SOX8 ENSG00000005513 "SRY-box transcription factor 8" P57073 16 981770-986979 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 92.6" "Group enriched" "Detected in some" 5 "Müller glia: 156.6;Oligodendrocyte progenitor cells: 161.8;Oligodendrocytes: 111.7" "Group enriched" "Detected in many" 8 "committed oligodendrocyte precursor: 225.9;oligodendrocyte: 85.8;oligodendrocyte precursor cell: 185.8" "Cancer enriched" "Detected in many" 7 "Glioblastoma Multiforme (TCGA): 104.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Rhabdoid: 9.3;Sarcoma: 29.1;skin cancer: 8.1" "Colon - Enteric glia cells, Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Fibroblasts, Skin - Eccrine sweat gland cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041640, HPA058665" Enhanced Nucleoplasm No NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" Nucleoplasm "HPA041640: , HPA058665: " "unprognostic (1.95e-2)" "unprognostic (5.79e-2)" "unprognostic (1.74e-2)" "unprognostic (9.93e-2)" "unprognostic (4.86e-2)" "potential prognostic favorable (4.62e-4)" "potential prognostic favorable (7.47e-4)" "unprognostic (2.07e-1)" "unprognostic (3.95e-1)" "unprognostic (9.55e-3)" "unprognostic (8.06e-2)" "unprognostic (2.24e-1)" "unprognostic (1.58e-2)" "unprognostic (6.21e-2)" "unprognostic (6.61e-2)" "unprognostic (1.18e-1)" "unprognostic (1.26e-1)" "unprognostic (2.37e-1)" SOX9 "CMD1, CMPD1, SRA1" ENSG00000125398 "SRY-box transcription factor 9" P48436 17 72121020-72126416 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 75.5" "Cell type enhanced" "Detected in many" "Breast lactating cells: 225.4;Breast secretory cells: 261.8;Ependymal cells: 223.1;Epididymal efferent duct absorptive cells: 349.0;Gastric progenitor cells: 205.1;Lacrimal acinar cells: 270.8;Mucous neck cells: 336.9;Pancreatic duct cells: 203.3;Parietal cells: 219.2;Prostatic club cells: 229.5;Retinal pigment epithelial cells: 234.5;Salivary ionocytes: 231.6;Tuft cells: 219.0" "Cell type enhanced" "Detected in many" "astrocyte: 193.5;ependymal cell: 258.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Cholangiocytes, Pituitary gland - Undifferentiated cells (Pituitary gland), Prostate - Prostate basal glandular cells, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001758, CAB022456, CAB068240, HPA070776" Enhanced Enhanced Nucleoplasm NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 39: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 16 Nucleoplasm "CAB022456: , CAB068240: , HPA001758: , HPA070776: " "unprognostic (2.34e-1)" "unprognostic (4.16e-2)" "unprognostic (5.80e-2)" "unprognostic (2.29e-3)" "unprognostic (1.17e-2)" "unprognostic (1.29e-1)" "unprognostic (1.34e-1)" "unprognostic (3.97e-3)" "unprognostic (7.66e-3)" "unprognostic (1.50e-1)" "unprognostic (2.39e-3)" "unprognostic (1.22e-2)" "unprognostic (5.23e-2)" "potential prognostic unfavorable (6.57e-4)" "unprognostic (2.63e-2)" "unprognostic (2.88e-3)" "unprognostic (4.21e-2)" "unprognostic (1.83e-2)" "unprognostic (2.77e-1)" "unprognostic (9.92e-2)" "unprognostic (8.70e-2)" "unprognostic (1.57e-2)" "unprognostic (2.43e-1)" "unprognostic (6.19e-2)" "unprognostic (1.13e-1)" "unprognostic (1.53e-1)" "unprognostic (4.58e-2)" "unprognostic (2.63e-2)" "unprognostic (9.80e-2)" "unprognostic (7.50e-2)" "unprognostic (1.12e-1)" SP1 ENSG00000185591 "Sp1 transcription factor" P08047 12 53380176-53416446 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Host-virus interaction, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 204.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000330, HPA001853, HPA012292" Supported Enhanced Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 54: Non-specific - Ribosome" "Cluster 25: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 24: Neutrophils - Innate immunity signal integration" 157 Nucleoplasm "CAB000330: , HPA001853: , HPA012292: " "unprognostic (1.67e-2)" "unprognostic (1.02e-1)" "unprognostic (3.56e-1)" "unprognostic (1.76e-1)" "unprognostic (1.14e-1)" "unprognostic (1.81e-2)" "unprognostic (3.77e-1)" "unprognostic (3.34e-2)" "unprognostic (6.17e-2)" "unprognostic (3.34e-3)" "potential prognostic favorable (3.54e-5)" "unprognostic (5.24e-2)" "unprognostic (1.99e-1)" "unprognostic (4.73e-3)" "unprognostic (9.10e-2)" "unprognostic (5.92e-2)" "unprognostic (7.56e-3)" "unprognostic (3.83e-2)" "unprognostic (1.05e-1)" "unprognostic (1.91e-2)" "unprognostic (2.53e-1)" "unprognostic (1.17e-3)" "unprognostic (1.24e-1)" "unprognostic (5.79e-2)" "unprognostic (1.42e-1)" "unprognostic (9.69e-2)" "unprognostic (1.46e-1)" "unprognostic (1.32e-1)" "unprognostic (1.91e-1)" "unprognostic (1.53e-2)" "unprognostic (6.98e-2)" SP100 ENSG00000067066 "SP100 nuclear antigen" P23497 2 230415942-230545606 "Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 177.8" "Cell type enhanced" "Detected in many" "B-cells: 782.2;Neutrophil progenitors: 538.4;Neutrophils: 1032.3" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 479.8;endothelial cell: 368.0;leukocyte: 380.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "HPA016707, HPA017384" Enhanced Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 8: Immune cells - Immune response" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 27 "Nuclear bodies" Nucleoplasm "HPA016707: , HPA017384: " "unprognostic (1.12e-3)" "unprognostic (1.35e-3)" "unprognostic (1.64e-2)" "unprognostic (2.73e-1)" "unprognostic (1.53e-1)" "unprognostic (1.03e-1)" "unprognostic (4.38e-2)" "unprognostic (7.52e-3)" "unprognostic (1.14e-2)" "unprognostic (7.03e-2)" "unprognostic (2.97e-3)" "unprognostic (3.01e-2)" "unprognostic (2.04e-1)" "unprognostic (2.37e-1)" "unprognostic (7.15e-3)" "unprognostic (5.90e-3)" "unprognostic (5.90e-2)" "unprognostic (8.43e-3)" "unprognostic (7.27e-3)" "unprognostic (1.99e-1)" "unprognostic (3.01e-1)" "unprognostic (1.36e-3)" "unprognostic (6.56e-3)" "unprognostic (2.63e-1)" "unprognostic (8.30e-2)" "unprognostic (1.74e-2)" "unprognostic (2.36e-2)" "unprognostic (6.15e-2)" "unprognostic (5.09e-2)" "unprognostic (2.22e-2)" "unprognostic (1.60e-1)" SP110 "IFI41, IFI75" ENSG00000135899 "SP110 nuclear body protein" Q9HB58 2 230165186-230225729 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 374.8;Breast lactating cells: 238.0;Neutrophils: 538.7;pDCs: 239.6" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 212.3;leukocyte: 164.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Skeletal muscle - Endothelial cells, Spleen - B-cells (Spleen), Thyroid gland - T-cells" "Low region specificity" "Detected in all" HPA058554 Supported Nucleoplasm No No "Cluster 20: Non-specific - DNA binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 7 Nucleoplasm "HPA058554: " "unprognostic (6.79e-3)" "unprognostic (1.66e-1)" "unprognostic (1.07e-1)" "unprognostic (3.73e-2)" "unprognostic (7.33e-2)" "unprognostic (3.17e-2)" "unprognostic (4.17e-2)" "unprognostic (5.15e-2)" "unprognostic (3.16e-2)" "unprognostic (1.52e-1)" "unprognostic (3.22e-2)" "unprognostic (1.05e-1)" "unprognostic (7.09e-3)" "unprognostic (6.45e-3)" "unprognostic (1.91e-2)" "unprognostic (1.27e-2)" "unprognostic (4.50e-2)" "unprognostic (1.57e-1)" "unprognostic (2.05e-1)" "unprognostic (2.98e-2)" "unprognostic (2.19e-1)" "potential prognostic unfavorable (3.79e-4)" "unprognostic (4.45e-3)" "unprognostic (4.31e-1)" "unprognostic (8.23e-2)" "unprognostic (3.34e-3)" "unprognostic (3.43e-1)" "unprognostic (1.94e-1)" "unprognostic (5.95e-2)" "unprognostic (1.77e-2)" "unprognostic (4.97e-2)" SP140 "LYSP100-A, LYSP100-B" ENSG00000079263 "SP140 nuclear body protein" Q13342 2 230203110-230313215 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 14.5;lymphoid tissue: 52.3" "Cell type enhanced" "Detected in many" "B-cells: 428.1;Innate lymphoid cells: 66.0;Microglia: 106.4;NK-cells: 153.9;Plasma cells: 190.3;T-cells: 215.7" "Group enriched" "Detected in all" 7 "central nervous system macrophage: 141.9;leukocyte: 140.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 97.8" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "lymphoma: 43.5;Myeloma: 18.6" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Prostate - T-cells, Spleen - B-cells (Spleen), Testis - Early spermatids, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006162, HPA067493" Enhanced Approved "Nucleoli fibrillar center,Mitochondria" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 4 "Nucleoli fibrillar center" Mitochondria "HPA006162: , HPA067493: " "potential prognostic favorable (9.14e-4)" "unprognostic (5.31e-3)" "unprognostic (4.95e-2)" "potential prognostic favorable (7.66e-6)" "unprognostic (6.93e-2)" "unprognostic (1.32e-1)" "unprognostic (5.17e-3)" "unprognostic (3.27e-1)" "unprognostic (1.92e-3)" "unprognostic (1.89e-3)" "unprognostic (3.59e-1)" "unprognostic (3.18e-3)" "unprognostic (2.51e-1)" "unprognostic (3.22e-2)" "unprognostic (3.03e-3)" "unprognostic (3.25e-1)" "unprognostic (8.62e-2)" "unprognostic (3.26e-1)" "unprognostic (2.66e-2)" "unprognostic (5.62e-2)" "unprognostic (2.78e-2)" "unprognostic (6.96e-3)" "unprognostic (2.14e-1)" "unprognostic (1.03e-2)" "unprognostic (1.37e-1)" "unprognostic (4.42e-2)" "unprognostic (8.00e-2)" "unprognostic (4.25e-2)" "unprognostic (3.98e-1)" "unprognostic (4.28e-1)" SP140L ENSG00000185404 "SP140 nuclear body protein like" Q9H930 2 230327184-230403732 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 157.9" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 97.3;endothelial cell: 54.0;leukocyte: 112.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - T-cells, Spleen - B-cells (Spleen), Thyroid gland - T-cells" HPA055864 Uncertain Approved Nucleoplasm NA NA "Cluster 32: Basophils - Transcription" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" Nucleoplasm "HPA055864: " "unprognostic (1.13e-2)" "unprognostic (7.33e-2)" "unprognostic (4.37e-2)" "unprognostic (3.60e-1)" "unprognostic (4.22e-3)" "unprognostic (6.20e-2)" "unprognostic (1.04e-1)" "unprognostic (1.45e-2)" "unprognostic (2.20e-3)" "potential prognostic unfavorable (7.88e-5)" "unprognostic (1.34e-1)" "unprognostic (1.13e-1)" "unprognostic (8.14e-2)" "potential prognostic unfavorable (4.08e-4)" "unprognostic (1.83e-1)" "unprognostic (5.00e-3)" "unprognostic (1.65e-1)" "unprognostic (2.33e-1)" "unprognostic (4.09e-1)" "unprognostic (7.84e-2)" "unprognostic (1.34e-1)" "unprognostic (2.58e-3)" "unprognostic (1.17e-3)" "unprognostic (1.77e-1)" "unprognostic (2.85e-1)" "unprognostic (1.65e-1)" "unprognostic (7.65e-2)" "unprognostic (1.13e-2)" "unprognostic (2.00e-1)" "unprognostic (3.31e-2)" "unprognostic (1.42e-1)" SP2 KIAA0048 ENSG00000167182 "Sp2 transcription factor" Q02086 17 47896150-47928957 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003357, CAB010245" Supported Supported Nucleoplasm,Vesicles NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 7 Nucleoplasm Vesicles "CAB010245: , HPA003357: " "unprognostic (6.15e-2)" "unprognostic (1.16e-1)" "unprognostic (2.91e-1)" "unprognostic (8.30e-2)" "unprognostic (1.26e-1)" "unprognostic (2.34e-2)" "unprognostic (9.61e-2)" "unprognostic (5.36e-2)" "unprognostic (3.22e-2)" "unprognostic (1.19e-2)" "potential prognostic favorable (1.73e-5)" "unprognostic (1.47e-3)" "unprognostic (1.99e-1)" "unprognostic (2.36e-2)" "unprognostic (4.13e-2)" "unprognostic (1.61e-1)" "unprognostic (4.56e-3)" "unprognostic (7.12e-2)" "unprognostic (2.94e-2)" "unprognostic (1.93e-2)" "unprognostic (2.24e-1)" "unprognostic (2.38e-1)" "unprognostic (3.03e-2)" "unprognostic (2.09e-1)" "unprognostic (4.46e-2)" "unprognostic (5.29e-2)" "unprognostic (1.64e-1)" "unprognostic (8.16e-2)" "unprognostic (2.17e-1)" "unprognostic (5.80e-2)" "unprognostic (7.17e-2)" SP3 SPR-2 ENSG00000172845 "Sp3 transcription factor" Q02447 2 173880850-173965373 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 449.6;Neutrophils: 919.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004580, HPA032145, HPA032146" Supported Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 23 Nucleoplasm Cytosol "CAB004580: , HPA032145: , HPA032146: " "unprognostic (8.08e-2)" "unprognostic (1.83e-1)" "unprognostic (1.68e-1)" "unprognostic (1.90e-1)" "unprognostic (3.04e-1)" "unprognostic (8.68e-2)" "unprognostic (2.74e-1)" "unprognostic (1.71e-1)" "unprognostic (1.65e-2)" "unprognostic (2.76e-2)" "potential prognostic favorable (1.70e-5)" "unprognostic (6.42e-2)" "unprognostic (3.81e-3)" "unprognostic (9.15e-3)" "unprognostic (4.55e-2)" "unprognostic (1.34e-2)" "unprognostic (2.19e-2)" "unprognostic (5.08e-2)" "unprognostic (3.28e-2)" "unprognostic (1.70e-1)" "unprognostic (1.70e-3)" "unprognostic (5.76e-3)" "unprognostic (5.59e-2)" "unprognostic (2.22e-1)" "unprognostic (4.21e-1)" "unprognostic (1.25e-1)" "unprognostic (1.39e-2)" "unprognostic (2.43e-1)" "unprognostic (1.94e-1)" "unprognostic (3.65e-2)" "unprognostic (3.66e-2)" SP4 "HF1B, MGC130008, MGC130009, SPR-1" ENSG00000105866 "Sp4 transcription factor" Q02446 7 21428043-21514822 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010246, HPA040395" Uncertain Enhanced Nucleoplasm,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 61: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 67: Non-specific - Unknown function" "Cluster 9: T-cells - Adaptive immunity: Regulation" 21 Nucleoplasm Cytosol "CAB010246: , HPA040395: " "unprognostic (4.54e-1)" "unprognostic (3.56e-2)" "unprognostic (1.34e-1)" "unprognostic (2.77e-2)" "unprognostic (6.17e-2)" "unprognostic (1.29e-1)" "unprognostic (1.31e-1)" "unprognostic (9.82e-2)" "unprognostic (1.11e-1)" "unprognostic (9.17e-2)" "potential prognostic favorable (7.38e-6)" "unprognostic (2.28e-3)" "unprognostic (8.37e-2)" "unprognostic (8.42e-2)" "unprognostic (6.36e-2)" "unprognostic (3.20e-1)" "unprognostic (2.31e-1)" "unprognostic (5.21e-2)" "unprognostic (9.61e-2)" "unprognostic (1.97e-2)" "unprognostic (2.03e-1)" "potential prognostic unfavorable (4.56e-4)" "unprognostic (1.22e-1)" "unprognostic (9.55e-2)" "unprognostic (1.98e-1)" "unprognostic (1.19e-1)" "unprognostic (2.26e-1)" "unprognostic (1.34e-1)" "unprognostic (2.12e-2)" "unprognostic (1.36e-1)" SP5 ENSG00000204335 "Sp5 transcription factor" Q6BEB4 2 170715337-170718078 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 6.0" "Cell type enhanced" "Detected in some" "Decidual stromal cells: 16.5;Endometrial stromal cells: 5.3;Epididymal basal cells: 11.9;Epididymal clear cells: 16.3;Epididymal efferent duct absorptive cells: 4.7;Fibroblasts: 6.5;Gastric chief cells: 12.0;Goblet cells: 5.6;Mucous neck cells: 4.7;Parietal cells: 10.6;Undifferentiated spermatogonia: 6.8" "Group enriched" "Detected in some" 4 "cerebellar inhibitory: 17.0;fibroblast: 11.6;midbrain-derived inhibitory: 10.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 12.1;colorectal cancer: 14.4;liver cancer: 12.4" "Liver - Hepatocytes, Skin - Fibroblasts_2, Testis - Spermatogonia" "Region enhanced" "Detected in single" "cerebellum: 1.1" "Low region specificity" "Detected in some" HPA074123 Approved Nucleoplasm,Nucleoli NA NA "Cluster 58: Skin - Keratinization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 108: Fibroblasts - ECM organization" Nucleoli Nucleoplasm "HPA074123: " "unprognostic (2.69e-2)" "unprognostic (2.54e-2)" "unprognostic (1.20e-2)" "unprognostic (2.89e-2)" "unprognostic (1.04e-2)" "unprognostic (2.32e-1)" "unprognostic (8.27e-2)" "unprognostic (1.47e-3)" "unprognostic (3.19e-3)" "unprognostic (1.44e-1)" "unprognostic (6.31e-2)" "unprognostic (1.83e-1)" "unprognostic (2.18e-1)" "unprognostic (2.19e-2)" "unprognostic (2.60e-1)" "unprognostic (3.62e-2)" "unprognostic (3.40e-2)" "unprognostic (6.45e-2)" "unprognostic (5.65e-3)" "unprognostic (1.05e-2)" "unprognostic (1.06e-2)" "unprognostic (2.37e-1)" "unprognostic (1.23e-3)" SP6 "Epfn, KLF14" ENSG00000189120 "Sp6 transcription factor" Q3SY56 17 47844908-47855874 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Amelogenesis imperfecta, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 21.4;skin 1: 13.9" "Cell type enhanced" "Detected in some" "Breast lactating cells: 25.3;Cytotrophoblasts: 70.2;Enterocytes: 14.1;Esophageal apical cells: 37.3;Migrating cytotrophoblasts: 34.6;Prostatic hillock cells: 13.7;Syncytiotrophoblasts: 108.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 18.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 33.9;colorectal cancer: 22.5" "Skin - Inner root sheath cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA024516, HPA044469" Supported "Nucleoplasm,Mitotic spindle,Centrosome" Yes No "Cluster 11: Esophagus - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 19 Nucleoplasm "Mitotic spindle, Centrosome" "HPA024516: , HPA044469: " "unprognostic (2.09e-1)" "unprognostic (5.92e-3)" "unprognostic (4.11e-2)" "unprognostic (7.43e-2)" "unprognostic (1.70e-2)" "unprognostic (1.89e-3)" "unprognostic (2.34e-2)" "potential prognostic unfavorable (7.08e-4)" "unprognostic (2.01e-1)" "unprognostic (4.91e-1)" "unprognostic (1.50e-2)" "potential prognostic unfavorable (1.83e-5)" "unprognostic (3.57e-1)" "unprognostic (3.06e-3)" "unprognostic (1.66e-1)" "unprognostic (5.65e-2)" "unprognostic (4.85e-3)" "unprognostic (8.09e-3)" "unprognostic (5.20e-3)" "unprognostic (1.79e-1)" "unprognostic (3.09e-2)" "unprognostic (1.61e-1)" "unprognostic (1.02e-1)" "potential prognostic favorable (3.30e-4)" "unprognostic (2.16e-1)" "unprognostic (6.41e-2)" SP7 "osterix, OSX" ENSG00000170374 "Sp7 transcription factor" Q8TDD2 12 53326575-53345315 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 4.1;Kupffer cells: 1.0;Retinal horizontal cells: 2.0;Thymocytes: 1.7" "Cell type enhanced" "Detected in single" "CGE interneuron: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Uterine cancer: 1.0" "Region enriched" "Detected in many" 5 "olfactory bulb: 28.1" "Region enhanced" "Detected in many" "olfactory bulb: 16.8" HPA063202 Enhanced NA NA "Cluster 11: White matter - Signal transduction" "Cluster 32: Non-specific - Cell proliferation" "Cluster 79: Photoreceptor cells - Phototransduction" 13 "HPA063202: " SP8 ENSG00000164651 "Sp8 transcription factor" Q8IXZ3 7 20782279-20786886 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "prostate: 6.0" "Group enriched" "Detected in some" 6 "Basal prostatic cells: 15.6;Prostatic glandular cells: 14.2" "Cell type enriched" "Detected in some" 7 "CGE interneuron: 13.7" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 8.3;Testicular Germ Cell Tumor (TCGA): 12.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Uterine cancer: 6.2" "Testis - Spermatogonia" "Group enriched" "Detected in many" 11 "basal ganglia: 15.3;olfactory bulb: 54.6" "Region enriched" "Detected in many" 12 "olfactory bulb: 40.7" HPA054006 Uncertain Approved Nucleoplasm NA NA "Cluster 38: Non-specific - Basic cellular processes" "Cluster 53: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" Nucleoplasm "HPA054006: " "unprognostic (2.61e-2)" "unprognostic (1.43e-1)" "unprognostic (1.73e-3)" "unprognostic (1.53e-1)" "unprognostic (1.35e-1)" "unprognostic (1.80e-2)" "unprognostic (3.59e-2)" "unprognostic (1.07e-1)" "unprognostic (7.06e-2)" SP9 ZNF990 ENSG00000217236 "Sp9 transcription factor" P0CG40 2 174334954-174338500 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.9;fallopian tube: 1.7" "Cell type enhanced" "Detected in some" "Brain inhibitory neurons: 6.4;Fibroblasts: 1.4;Gastric progenitor cells: 1.3;Other brain neurons: 2.5;Respiratory ionocytes: 5.1" "Cell type enhanced" "Detected in some" "CGE interneuron: 12.0;eccentric medium spiny neuron: 16.9;LAMP5-LHX6 and Chandelier: 31.6;MGE interneuron: 12.3" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 3.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Adrenocortical cancer: 3.3;Rhabdoid: 2.6" "Group enriched" "Detected in many" 6 "basal ganglia: 5.8;olfactory bulb: 11.7" "Group enriched" "Detected in many" 5 "basal ganglia: 9.1;olfactory bulb: 35.1" HPA062616 Uncertain Approved Mitochondria NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 109: Neurons - Neuronal signaling" Mitochondria "HPA062616: " "unprognostic (2.13e-3)" "unprognostic (3.77e-1)" "unprognostic (2.82e-1)" "unprognostic (1.25e-1)" SPA17 "CT22, SP17" ENSG00000064199 "Sperm autoantigenic protein 17" Q15506 11 124673844-124697518 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 23.1;testis: 36.7" "Group enriched" "Detected in many" 4 "Early spermatids: 1487.2;Late primary spermatocytes: 1868.7;Late spermatids: 3590.4" "Group enriched" "Detected in many" 5 "choroid plexus epithelial cell: 36.6;ependymal cell: 119.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Liver - Vascular endothelial cells, Lung - Respiratory ciliated cells, Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037568 Enhanced Approved "Golgi apparatus,Vesicles,Principal piece" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 13 "Golgi apparatus, Principal piece" Vesicles "HPA037568: " "unprognostic (6.03e-2)" "unprognostic (9.37e-2)" "unprognostic (1.16e-1)" "unprognostic (1.75e-1)" "potential prognostic favorable (5.52e-4)" "unprognostic (1.04e-2)" "unprognostic (2.77e-1)" "unprognostic (5.94e-3)" "unprognostic (6.12e-2)" "potential prognostic favorable (5.53e-5)" "unprognostic (2.84e-2)" "unprognostic (4.98e-3)" "unprognostic (4.96e-2)" "unprognostic (7.32e-2)" "unprognostic (7.58e-2)" "unprognostic (1.88e-1)" "unprognostic (1.23e-1)" "unprognostic (8.29e-2)" "unprognostic (1.46e-1)" "unprognostic (1.74e-1)" "unprognostic (1.04e-1)" "unprognostic (5.23e-2)" "unprognostic (6.08e-2)" "unprognostic (1.78e-1)" "unprognostic (2.42e-1)" "unprognostic (2.04e-1)" "unprognostic (1.56e-2)" "unprognostic (1.31e-1)" "unprognostic (1.91e-2)" SPAAR "LINC00961, SPAR" ENSG00000235387 "Small regulatory polypeptide of amino acid response" A0A1B0GVQ0 9 35909490-35937153 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 11.7;breast: 10.5;heart muscle: 8.7" "Cell type enhanced" "Detected in some" "Adipocytes: 45.3;Fibro-adipogenic progenitors: 40.4;Retinal bipolar cells: 16.8;Sertoli cells: 178.8;Vascular endothelial cells: 56.0" "Cell type enriched" "Detected in many" 6 "endothelial cell: 75.8" "Cancer enhanced" "Detected in some" "Kidney Renal Clear Cell Carcinoma (TCGA): 5.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 11.4;Sarcoma: 4.1" "Adipose visceral - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Liver - Vascular endothelial cells, Testis - Sertoli cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 5: Rhabdoid - Unknown function" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" "unprognostic (3.20e-1)" "unprognostic (7.36e-2)" "unprognostic (1.51e-2)" "potential prognostic favorable (2.10e-7)" "unprognostic (3.87e-2)" "unprognostic (7.04e-3)" "unprognostic (2.37e-1)" "unprognostic (1.12e-1)" "unprognostic (8.06e-2)" SPACA1 SAMP32 ENSG00000118434 "Sperm acrosome associated 1" Q9HBV2 6 88047841-88066838 "Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 395 "testis: 39.5" "Group enriched" "Detected in some" 15 "Early spermatids: 1083.0;Late primary spermatocytes: 660.9" "Cell type enhanced" "Detected in single" "hippocampal CA4: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA026744, HPA043297" Enhanced Supported Acrosome NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 36 Acrosome "HPA026744: , HPA043297: " SPACA3 "ALLP17, CT54, LYC3, LYZL3, SLLP1" ENSG00000141316 "Sperm acrosome associated 3" Q8IXA5 17 32970376-32997877 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 117.7" "Group enriched" "Detected in some" 56 "Early spermatids: 1520.6;Late primary spermatocytes: 614.4;Late spermatids: 1392.8" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rectum Adenocarcinoma (TCGA): 2.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "memory B-cell: 1.2" "Lineage enriched" "Detected in single" 5 "B-cells: 1.2" "Cancer enriched" "Detected in single" 11 "Myeloma: 8.3" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA023633 Enhanced Approved Acrosome "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 21: Testis - Mixed function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 1 Acrosome "HPA023633: " "unprognostic (4.38e-1)" "unprognostic (7.48e-2)" "unprognostic (1.88e-3)" "unprognostic (1.01e-2)" "unprognostic (1.02e-1)" SPACA4 SAMP14 ENSG00000177202 "Sperm acrosome associated 4" Q8TDM5 19 48606742-48607714 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 33 "testis: 111.8" "Group enriched" "Detected in some" 4 "Early spermatids: 1273.7;Late primary spermatocytes: 404.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "colorectal cancer: 1.3" "Colon - Colon enterocytes, Prostate - Urothelial cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041927, HPA061302" Enhanced Enhanced Acrosome NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" Acrosome "HPA041927: , HPA061302: " "unprognostic (2.69e-1)" "potential prognostic favorable (4.57e-4)" "unprognostic (2.35e-1)" "unprognostic (7.85e-2)" "unprognostic (1.04e-1)" "unprognostic (2.62e-1)" "unprognostic (1.01e-1)" "unprognostic (9.87e-3)" "unprognostic (5.04e-1)" SPACA5 "dJ54B20.3, LYC5, LYZL5, PNPK6288, SLLP2, UNQ6288" ENSG00000171489 "Sperm acrosome associated 5" Q96QH8 X 48004336-48009733 "Enzymes, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "testis: 1.0" "Cell type enhanced" "Detected in some" "Loop of henle epithelial cells: 1.1;Renal collecting duct intercalated cells: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "Sarcoma: 1.7" "HPA044747, HPA047149" Supported "Secreted in male reproductive system" Enzyme NA NA "Cluster 21: Testis - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 54: Non-specific - Transcription" "Cluster 105: Non-specific - Mixed function" "HPA044747: , HPA047149: " "unprognostic (8.37e-2)" SPACA5B LYZL5B ENSG00000171478 "Sperm acrosome associated 5B" Q96QH8 X 48130626-48132620 "Enzymes, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 93 "testis: 34.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA044747, HPA047149" Supported "Secreted in male reproductive system" Enzyme NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 54: Non-specific - Transcription" "HPA044747: , HPA047149: " SPACA6 "LET7EH, LINC00085, NCRNA00085, SPACA6P" ENSG00000182310 "Sperm acrosome associated 6" W5XKT8 19 51689128-51712387 "Predicted intracellular proteins, Predicted membrane proteins" Fertilization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 6.2" "Cell type enriched" "Detected in many" 6 "Epicardial cells: 2174.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 67: Testis - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 72: Neuronal - Signal transduction" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 1 "unprognostic (4.45e-2)" "unprognostic (2.21e-1)" "unprognostic (7.42e-2)" "unprognostic (1.75e-1)" "unprognostic (4.21e-3)" "unprognostic (3.05e-1)" SPACA7 C13orf28 ENSG00000153498 "Sperm acrosome associated 7" Q96KW9 13 112376355-112434689 "Predicted intracellular proteins, Predicted secreted proteins" Fertilization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 161 "testis: 83.8" "Group enriched" "Detected in some" 301 "Early spermatids: 1322.6;Late primary spermatocytes: 553.2;Late spermatids: 934.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.0" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.0" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" HPA048349 Enhanced Approved "Microtubules,Mitochondria,Acrosome,Equatorial segment,Principal piece,End piece" "Secreted in male reproductive system" Other NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 79: Testis - Spermatogenesis" "Cluster 48: Non-specific - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" "Microtubules, Acrosome" "Mitochondria, Equatorial segment, Principal piece, End piece" "HPA048349: " SPACA9 "C9orf9, Mast" ENSG00000165698 "Sperm acrosome associated 9" Q96E40 9 132878027-132890201 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "epididymis: 69.8;fallopian tube: 36.8;testis: 124.6" "Group enriched" "Detected in many" 4 "Early spermatids: 2418.5;Late spermatids: 2904.4" "Cell type enhanced" "Detected in all" "ependymal cell: 57.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Prostate - Fibroblasts, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA022243, HPA051600" Enhanced Supported "Vesicles,Cytosol,End piece" NA No "Cluster 24: Non-specific - Transcription" "Cluster 22: Epididymis - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 9 Vesicles "Cytosol, End piece" "HPA022243: , HPA051600: " "unprognostic (3.09e-2)" "unprognostic (1.07e-1)" "unprognostic (2.18e-2)" "unprognostic (3.99e-3)" "unprognostic (6.93e-3)" "unprognostic (2.18e-1)" "unprognostic (1.78e-1)" "unprognostic (9.48e-2)" "unprognostic (1.28e-1)" "unprognostic (2.94e-3)" "unprognostic (4.68e-2)" "unprognostic (1.17e-2)" "unprognostic (1.43e-3)" "unprognostic (6.16e-2)" "unprognostic (3.10e-1)" "unprognostic (3.08e-2)" "unprognostic (9.48e-2)" "unprognostic (3.24e-1)" "unprognostic (5.48e-2)" "unprognostic (1.51e-1)" "unprognostic (9.40e-2)" "unprognostic (5.84e-2)" "unprognostic (4.85e-2)" "unprognostic (1.42e-2)" "unprognostic (7.61e-2)" "unprognostic (1.98e-1)" "unprognostic (2.43e-2)" "unprognostic (8.34e-2)" "unprognostic (1.37e-3)" SPACDR "C7orf61, IMAGE:4839025" ENSG00000185955 "Sperm acrosome developmental regulator" Q8IZ16 7 100456620-100464260 "Disease related genes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "testis: 66.0" "Group enriched" "Detected in many" 14 "Early spermatids: 556.4;Late primary spermatocytes: 436.5;Late spermatids: 448.0" "Cell type enhanced" "Detected in many" "astrocyte: 35.9;oligodendrocyte: 21.5" "Cancer enriched" "Detected in many" 5 "Glioblastoma Multiforme (TCGA): 12.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" HPA060395 Enhanced Approved Vesicles,Acrosome NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 67: Testis - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" "Vesicles, Acrosome" "HPA060395: " "unprognostic (1.46e-2)" "unprognostic (1.91e-1)" "unprognostic (3.31e-1)" "unprognostic (7.87e-2)" "unprognostic (5.39e-3)" "unprognostic (3.41e-2)" "unprognostic (1.48e-2)" "unprognostic (3.17e-1)" "unprognostic (7.00e-2)" "unprognostic (1.85e-2)" "unprognostic (2.40e-3)" SPAG1 "CILD28, CT140, DNAAF13, FLJ32920, HSD-3.8, SP75, TPIS" ENSG00000104450 "Sperm associated antigen 1" Q07617 8 100157906-100259278 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Fertilization Hydrolase "Ciliopathy, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 294.0;Endometrial ciliated cells: 598.4;Ependymal cells: 413.4;Epididymal efferent duct ciliated cells: 452.4;Fallopian tube ciliated cells: 413.7;Respiratory ciliated cells: 455.8;Somatotrophs: 269.3" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 281.0;ependymal cell: 465.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells, Skin - Keratinocyte (granular), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023748, HPA053682" Enhanced Supported "Primary cilium,Cytosol,Principal piece" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 44: Non-specific - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 51: Secretory epithelial cells - Mixed function" 5 "Primary cilium, Cytosol, Principal piece" "HPA023748: , HPA053682: " "unprognostic (4.48e-2)" "unprognostic (7.59e-2)" "unprognostic (3.73e-1)" "unprognostic (6.43e-2)" "unprognostic (9.67e-2)" "unprognostic (1.25e-2)" "unprognostic (1.16e-1)" "unprognostic (8.26e-2)" "unprognostic (3.58e-1)" "unprognostic (1.23e-2)" "unprognostic (3.75e-3)" "unprognostic (2.71e-1)" "unprognostic (1.05e-2)" "unprognostic (1.88e-2)" "unprognostic (6.15e-2)" "unprognostic (5.87e-3)" "unprognostic (6.96e-3)" "unprognostic (1.02e-1)" "unprognostic (1.00e-2)" "unprognostic (3.54e-1)" "unprognostic (2.65e-1)" "unprognostic (1.72e-1)" "unprognostic (1.81e-2)" "unprognostic (1.09e-1)" "unprognostic (9.02e-2)" "unprognostic (1.31e-1)" "unprognostic (2.18e-1)" "unprognostic (1.84e-2)" "unprognostic (1.12e-1)" "unprognostic (3.12e-2)" "unprognostic (8.92e-3)" SPAG11A "EDDM2A, HE2" ENSG00000178287 "Sperm associated antigen 11A" Q6PDA7 8 7847876-7868867 "Predicted intracellular proteins, Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 11416 "epididymis: 4487.2" "Cell type enriched" "Detected in some" 47 "Epididymal principal cells: 4477.7" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Lung Adenocarcinoma (TCGA): 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 64 "Uterine cancer: 6.4" "HPA023842, HPA057479" Supported Approved "Golgi apparatus" "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 15: Kidney cancer - Membrane components" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" "Golgi apparatus" "HPA023842: , HPA057479: " SPAG11B "EDDM2B, EP2, EP2C, EP2D, HE2" ENSG00000164871 "Sperm associated antigen 11B" Q08648 8 7442684-7463674 "Predicted intracellular proteins, Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1939 "epididymis: 1188.1" "Cell type enriched" "Detected in some" 16 "Epididymal principal cells: 7109.2" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "Lung Adenocarcinoma (TCGA): 1.2;Ovary Serous Cystadenocarcinoma (TCGA): 1.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 47 "Uterine cancer: 6.9" "HPA023842, HPA057479" Supported Approved "Golgi apparatus" "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 15: Kidney cancer - Membrane components" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" "Golgi apparatus" "HPA023842: , HPA057479: " "unprognostic (3.14e-1)" "unprognostic (1.19e-1)" SPAG16 "DKFZp666P1710, FLJ22724, PF20, WDR29" ENSG00000144451 "Sperm associated antigen 16" Q8N0X2 2 213284389-214410501 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 799.1;Endometrial ciliated cells: 815.8;Ependymal cells: 1818.4;Fallopian tube ciliated cells: 867.9;Lactotrophs: 1280.6;Respiratory ciliated cells: 1623.0;Somatotrophs: 1585.4;Thyrotrophs: 2509.2" "Cell type enhanced" "Detected in all" "ependymal cell: 1980.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Skeletal muscle - Fibroblasts, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA037542 Approved Approved "Vesicles,Plasma membrane,Cytosol,Acrosome,Equatorial segment" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 39: Astrocytes - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" "Cytosol, Equatorial segment" "Vesicles, Plasma membrane, Acrosome" "HPA037542: " "unprognostic (1.91e-1)" "unprognostic (5.21e-3)" "unprognostic (5.51e-2)" "unprognostic (4.79e-2)" "unprognostic (1.40e-2)" "unprognostic (5.63e-2)" "unprognostic (1.72e-1)" "unprognostic (5.98e-2)" "unprognostic (1.51e-1)" "unprognostic (2.07e-1)" "potential prognostic favorable (1.06e-5)" "unprognostic (3.22e-2)" "unprognostic (2.07e-1)" "unprognostic (2.10e-2)" "unprognostic (1.45e-2)" "unprognostic (3.17e-1)" "unprognostic (5.20e-2)" "unprognostic (2.79e-1)" "unprognostic (5.03e-1)" "unprognostic (2.73e-1)" "unprognostic (2.04e-1)" "unprognostic (1.03e-1)" "unprognostic (1.20e-1)" "potential prognostic unfavorable (3.51e-4)" "unprognostic (3.35e-2)" "unprognostic (1.01e-1)" "unprognostic (1.61e-1)" "unprognostic (7.21e-3)" "unprognostic (8.25e-2)" "unprognostic (1.32e-1)" "unprognostic (6.03e-2)" SPAG17 "CT143, FLJ34497, PF6, RP4-776P7.2" ENSG00000155761 "Sperm associated antigen 17" Q6Q759 1 117953590-118185228 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 25.7;testis: 14.0" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 722.0;Early spermatids: 285.2;Endometrial ciliated cells: 874.0;Ependymal cells: 1673.1;Epididymal efferent duct ciliated cells: 675.3;Fallopian tube ciliated cells: 683.9;Late primary spermatocytes: 257.9;Late spermatids: 648.3;Respiratory ciliated cells: 1267.8" "Group enriched" "Detected in all" 17 "choroid plexus epithelial cell: 606.0;ependymal cell: 1720.2" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "choroid plexus: 56.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 1.3" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Region enhanced" "Detected in many" "midbrain: 14.2" "HPA028597, HPA028666" Enhanced Approved "Equatorial segment,Mid piece,Principal piece" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 15: Kidney cancer - Membrane components" "Cluster 34: Ciliated cells - Cilia assembly & function" 2 "Mid piece, Principal piece" "Equatorial segment" "HPA028597: , HPA028666: " "unprognostic (3.14e-2)" "unprognostic (3.76e-2)" "unprognostic (1.70e-1)" "unprognostic (4.73e-3)" "potential prognostic unfavorable (2.90e-5)" "unprognostic (8.17e-2)" "potential prognostic unfavorable (3.40e-4)" "unprognostic (5.30e-2)" "unprognostic (3.85e-3)" "potential prognostic unfavorable (4.60e-5)" "unprognostic (2.08e-2)" "unprognostic (8.09e-2)" "unprognostic (3.07e-1)" "unprognostic (1.41e-1)" "unprognostic (2.23e-2)" "unprognostic (7.94e-3)" "unprognostic (2.73e-2)" SPAG4 "CT127, SUN4" ENSG00000061656 "Sperm associated antigen 4" Q9NPE6 20 35615829-35621094 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "pancreas: 85.0;testis: 30.4" "Cell type enhanced" "Detected in many" "Early spermatids: 216.4;Epicardial cells: 54.6;Late primary spermatocytes: 67.3;Late spermatids: 189.5;Pancreatic acinar cells: 56.3;Plasma cells: 343.5" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 62.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.2" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Breast - Plasma cells, Minor Salivary Gland - Plasma cells, Spleen - Plasma cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA048393, HPA061789" Approved NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 8: Pancreas - Proteolysis" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 44: Plasma cells - Antibody production & secretion" 25 "HPA048393: , HPA061789: " "unprognostic (3.76e-1)" "unprognostic (1.80e-1)" "unprognostic (6.20e-2)" "unprognostic (9.85e-3)" "unprognostic (1.00e-2)" "potential prognostic favorable (2.34e-4)" "validated prognostic unfavorable (3.40e-4)" "validated prognostic unfavorable (1.33e-4)" "unprognostic (2.82e-1)" "unprognostic (2.01e-2)" "unprognostic (5.46e-2)" "unprognostic (1.77e-1)" "unprognostic (7.49e-2)" "unprognostic (3.14e-3)" "unprognostic (2.77e-2)" "unprognostic (4.97e-2)" "unprognostic (1.19e-1)" "unprognostic (1.70e-2)" "unprognostic (2.11e-2)" "unprognostic (3.07e-2)" "unprognostic (2.00e-1)" "unprognostic (1.05e-3)" "unprognostic (3.71e-2)" "unprognostic (1.74e-1)" "unprognostic (1.86e-2)" "unprognostic (1.34e-2)" "unprognostic (2.74e-2)" "unprognostic (4.75e-2)" "unprognostic (2.72e-1)" "unprognostic (3.44e-1)" "unprognostic (1.76e-1)" SPAG5 "DEEPEST, hMAP126, MAP126" ENSG00000076382 "Sperm associated antigen 5" Q96R06 17 28577565-28599025 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 35.7;kidney: 37.6;testis: 72.1" "Group enriched" "Detected in many" 4 "Early spermatids: 121.1;Late primary spermatocytes: 164.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 11.7;T-reg: 5.0" "Group enriched" "Detected in many" 6 "granulocytes: 11.7;T-cells: 5.0" "Low cancer specificity" "Detected in all" "Heart muscle - Mitotic cells (Heart), Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA022008, HPA022479, HPA024418" Approved Supported "Nuclear bodies,Mitotic spindle,Cytosol" Yes Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 39: Testis - Nuclear processes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 63 "Nuclear bodies, Mitotic spindle" Cytosol "HPA022008: , HPA022479: , HPA024418: " "unprognostic (1.54e-2)" "unprognostic (1.18e-2)" "unprognostic (2.73e-1)" "unprognostic (2.03e-2)" "unprognostic (1.41e-2)" "unprognostic (1.41e-1)" "unprognostic (2.14e-1)" "unprognostic (7.67e-3)" "unprognostic (1.29e-1)" "potential prognostic unfavorable (3.19e-5)" "unprognostic (9.81e-3)" "unprognostic (1.10e-1)" "potential prognostic unfavorable (1.76e-4)" "validated prognostic unfavorable (2.12e-5)" "validated prognostic unfavorable (8.67e-7)" "potential prognostic unfavorable (1.34e-5)" "unprognostic (2.54e-2)" "unprognostic (6.48e-2)" "unprognostic (1.68e-3)" "unprognostic (1.32e-1)" "unprognostic (1.14e-1)" "potential prognostic unfavorable (7.56e-4)" "unprognostic (1.12e-2)" "unprognostic (3.71e-2)" "unprognostic (5.91e-2)" "unprognostic (2.52e-2)" "unprognostic (4.05e-2)" "unprognostic (2.88e-1)" "unprognostic (1.89e-1)" "unprognostic (1.54e-2)" "unprognostic (4.43e-2)" SPAG6 "CFAP194, CT141, FAP194, PF16, Repro-SA-1" ENSG00000077327 "Sperm associated antigen 6" O75602 10 22345445-22454224 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "choroid plexus: 94.1;fallopian tube: 46.1;testis: 90.0" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 181.0;Early primary spermatocytes: 430.2;Early spermatids: 156.1;Endometrial ciliated cells: 119.2;Ependymal cells: 335.3;Epididymal efferent duct ciliated cells: 304.3;Fallopian tube ciliated cells: 307.0;Late primary spermatocytes: 801.2;Respiratory ciliated cells: 361.5" "Group enriched" "Detected in all" 21 "choroid plexus epithelial cell: 187.3;ependymal cell: 429.4" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 5.9" "Region enhanced" "Detected in all" "choroid plexus: 133.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 7.4;Myeloma: 6.8;Rhabdoid: 4.6" "Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Pancreas - Beta cells, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Testis - Early spermatids" "Low region specificity" "Detected in single" "Region enhanced" "Detected in many" "midbrain: 14.7" HPA038440 Enhanced Supported "Calyx,Mid piece,Principal piece,End piece" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 65: Non-specific - Unknown function" "Cluster 3: Early primary spermatocytes - Early meiosis" "Calyx, Mid piece, Principal piece, End piece" "HPA038440: " "unprognostic (1.66e-1)" "unprognostic (2.02e-3)" "unprognostic (1.83e-3)" "unprognostic (4.42e-2)" "unprognostic (1.12e-1)" "unprognostic (1.46e-1)" "unprognostic (2.15e-1)" "unprognostic (2.69e-2)" "unprognostic (2.43e-1)" "unprognostic (3.28e-1)" "unprognostic (3.09e-2)" "unprognostic (2.14e-1)" "unprognostic (1.03e-2)" SPAG7 "ACRP, FSA-1, MGC20134" ENSG00000091640 "Sperm associated antigen 7" O75391 17 4959226-4967817 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 286.1" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 246.8;Syncytiotrophoblasts: 272.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024032, HPA052394" Uncertain Supported Nucleoplasm NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 27: Non-specific - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 2 Nucleoplasm "HPA024032: , HPA052394: " "unprognostic (1.50e-1)" "unprognostic (1.04e-1)" "unprognostic (1.23e-2)" "unprognostic (1.94e-2)" "unprognostic (2.58e-1)" "unprognostic (3.08e-2)" "unprognostic (2.58e-3)" "unprognostic (4.32e-1)" "unprognostic (2.66e-1)" "unprognostic (9.16e-2)" "potential prognostic favorable (1.03e-5)" "unprognostic (1.95e-3)" "potential prognostic favorable (1.01e-4)" "unprognostic (1.06e-1)" "unprognostic (2.76e-2)" "unprognostic (2.02e-2)" "unprognostic (1.18e-1)" "unprognostic (3.42e-2)" "unprognostic (2.84e-1)" "unprognostic (2.34e-1)" "unprognostic (6.28e-2)" "unprognostic (5.00e-2)" "unprognostic (2.29e-2)" "unprognostic (3.73e-1)" "unprognostic (8.65e-3)" "unprognostic (9.63e-2)" "unprognostic (1.53e-1)" "potential prognostic unfavorable (9.90e-4)" "unprognostic (1.99e-1)" "unprognostic (7.05e-2)" "unprognostic (8.57e-2)" SPAG8 "BS-84, CT142, HSD-1, hSMP-1, SPAG3" ENSG00000137098 "Sperm associated antigen 8" Q99932 9 35808045-35812272 "Predicted intracellular proteins" "Cell cycle, Differentiation, Fertilization, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "choroid plexus: 10.7;fallopian tube: 13.4;testis: 8.2" "Group enriched" "Detected in many" 4 "Choroid plexus epithelial cells: 102.9;Endometrial ciliated cells: 101.0;Ependymal cells: 323.4;Epididymal efferent duct ciliated cells: 133.0;Fallopian tube ciliated cells: 180.9;Late primary spermatocytes: 137.8;Respiratory ciliated cells: 172.3" "Group enriched" "Detected in all" 15 "choroid plexus epithelial cell: 166.8;ependymal cell: 346.8" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in all" "choroid plexus: 33.4" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Colon - Enteric glia cells, Lung - Respiratory ciliated cells, Skeletal muscle - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA068012 Enhanced Supported "Nucleoplasm,Primary cilium,Cytosol,Acrosome,Equatorial segment,Principal piece,End piece" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" 4 "Primary cilium, Acrosome, Equatorial segment, End piece" "Nucleoplasm, Cytosol, Principal piece" "HPA068012: " "unprognostic (1.51e-1)" "unprognostic (1.96e-1)" "unprognostic (1.42e-1)" "unprognostic (2.76e-2)" "unprognostic (1.11e-3)" "unprognostic (1.32e-1)" "unprognostic (1.20e-2)" "unprognostic (8.42e-2)" SPAG9 "CT89, FLJ13450, FLJ14006, FLJ26141, FLJ34602, HLC4, HSS, JIP-4, JIP4, JLP, KIAA0516, MGC117291, MGC14967, MGC74461, PHET, PIG6, SYD1" ENSG00000008294 "Sperm associated antigen 9" O60271 17 50962174-51120868 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial glandular cells: 1576.5;Neutrophils: 2267.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 9.2;neutrophil: 12.3" "Lineage enriched" "Detected in many" 7 "granulocytes: 12.3" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040446, HPA061458" Enhanced Enhanced "Centriolar satellite,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 22 "Centriolar satellite, Cytosol" "HPA040446: , HPA061458: " "unprognostic (3.38e-1)" "unprognostic (3.57e-2)" "unprognostic (3.06e-2)" "unprognostic (1.06e-2)" "unprognostic (1.29e-1)" "potential prognostic unfavorable (7.43e-4)" "unprognostic (1.91e-1)" "unprognostic (8.96e-3)" "unprognostic (1.10e-1)" "unprognostic (3.41e-3)" "validated prognostic favorable (2.44e-7)" "validated prognostic favorable (1.46e-4)" "unprognostic (1.22e-2)" "unprognostic (1.10e-1)" "unprognostic (1.28e-2)" "unprognostic (3.00e-1)" "unprognostic (7.03e-2)" "unprognostic (1.86e-2)" "unprognostic (2.30e-1)" "unprognostic (1.23e-1)" "unprognostic (1.08e-2)" "unprognostic (9.22e-3)" "potential prognostic unfavorable (4.25e-5)" "unprognostic (8.38e-2)" "unprognostic (1.13e-1)" "potential prognostic favorable (1.32e-6)" "unprognostic (3.16e-1)" "unprognostic (2.03e-2)" "unprognostic (4.88e-1)" "unprognostic (3.39e-2)" "unprognostic (1.55e-1)" SPAM1 "HYAL5, PH-20, SPAG15" ENSG00000106304 "Sperm adhesion molecule 1" P38567 7 123925237-123971414 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 37 "testis: 16.2" "Group enriched" "Detected in some" 39 "Early spermatids: 352.3;Late primary spermatocytes: 116.7;Late spermatids: 187.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA017984 Enhanced NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" "HPA017984: " SPANXA1 "CT11.1, NAP-X, SPAN-Xa, SPAN-Xb, SPANX" ENSG00000198021 "Sperm protein associated with the nucleus, X-linked, family member A1" Q9NS26 X 141583674-141584738 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 44 "testis: 4.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 6.2;Sarcoma: 17.4" "HPA046423, HPA073647" Supported Approved Nucleoplasm,Vesicles NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" 1 Nucleoplasm Vesicles "HPA046423: , HPA073647: " SPANXA2 SPANX ENSG00000203926 "SPANX family member A2" Q9NS26 X 141589708-141590762 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 613 "testis: 61.3" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder Urothelial Carcinoma (TCGA): 8.3;Breast Invasive Carcinoma (TCGA): 13.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 90.0;Sarcoma: 264.1" "HPA046423, HPA073647" Supported Approved Nucleoplasm,Vesicles NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 72: Neuronal - Signal transduction" 1 Nucleoplasm Vesicles "HPA046423: , HPA073647: " "unprognostic (6.51e-1)" "unprognostic (4.61e-1)" "unprognostic (1.35e-3)" "unprognostic (1.38e-1)" "unprognostic (1.18e-1)" "unprognostic (1.60e-1)" SPANXB1 "CT11.2, SPANXB2, SPANXF1, SPANXF2" ENSG00000227234 "SPANX family member B1" Q9NS25 X 141002594-141003706 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 85 "testis: 86.5" "Cell type enriched" "Detected in some" 4 "Late spermatids: 2940.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder Urothelial Carcinoma (TCGA): 11.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder cancer: 48.2;Sarcoma: 61.8" "Adipose visceral - Mesothelial cells, Testis - Late spermatids" "HPA046423, HPA073647" Supported Uncertain Nucleoplasm,Vesicles NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 11: White matter - Signal transduction" "Cluster 72: Neuronal - Signal transduction" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 4 Nucleoplasm Vesicles "HPA046423: , HPA073647: " "unprognostic (5.65e-1)" "unprognostic (6.34e-3)" "unprognostic (3.55e-3)" "unprognostic (1.41e-1)" SPANXC "CT11.3, CTp11" ENSG00000198573 "SPANX family member C" Q9NY87 X 141241463-141242517 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 305 "testis: 30.4" "Cell type enriched" "Detected in some" 4 "Late spermatids: 2256.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Head and Neck Squamous Cell Carcinoma (TCGA): 1.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 14.0;Sarcoma: 18.0" "HPA046423, HPA073647" Supported Approved Nucleoplasm,Vesicles NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 2 Nucleoplasm Vesicles "HPA046423: , HPA073647: " "unprognostic (1.38e-1)" "unprognostic (1.12e-2)" "unprognostic (2.60e-1)" SPANXD "CT11.4, SPANXE" ENSG00000196406 "SPANX family member D" Q9BXN6 X 141697411-141698739 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 207 "testis: 20.7" "Cell type enriched" "Detected in some" 4 "Late spermatids: 2100.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Bile duct cancer: 65.2;Sarcoma: 26.3" "Testis - Late spermatids" "HPA046423, HPA073647" Supported Approved Nucleoplasm,Vesicles NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 1 Nucleoplasm Vesicles "HPA046423: , HPA073647: " SPANXN1 "CT11.6, SPANX-N1" ENSG00000203923 "SPANX family member N1" Q5VSR9 X 145247503-145256208 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 28 "testis: 2.8" "Cell type enhanced" "Detected in some" "Early spermatids: 9.3;Late primary spermatocytes: 4.7;Late spermatids: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "thyroid cancer: 1.0" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 72: Neuronal - Signal transduction" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" SPANXN2 "CT11.7, SPANX-N2" ENSG00000268988 "SPANX family member N2" Q5MJ10 X 143711955-143720752 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 34 "testis: 3.3" "Group enriched" "Detected in some" 15 "Early spermatids: 63.0;Late spermatids: 160.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045652 Uncertain "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 69: Skin cancer - ECM organization" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 39 Nucleoplasm "Nucleoli fibrillar center" "HPA045652: " SPANXN3 "CT11.8, SPANX-N3" ENSG00000189252 "SPANX family member N3" Q5MJ09 X 143508735-143517475 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 57 "testis: 47.4" "Group enriched" "Detected in some" 120 "Early spermatids: 475.6;Late primary spermatocytes: 332.3;Late spermatids: 316.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "thyroid cancer: 2.7" HPA045652 Uncertain "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 11 Nucleoplasm "Nucleoli fibrillar center" "HPA045652: " SPANXN4 "CT11.9, SPANX-N4" ENSG00000189326 "SPANX family member N4" Q5MJ08 X 143025928-143034702 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 249 "testis: 24.8" "Group enriched" "Detected in some" 8 "Early spermatids: 94.3;Late spermatids: 366.3" "Cell type enhanced" "Detected in single" "hippocampal dentate gyrus: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045730, HPA059094" Uncertain Uncertain "Nuclear membrane,Vesicles,Plasma membrane" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 47: Leukemia - Hemostasis" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" "Vesicles, Plasma membrane" "Nuclear membrane" "HPA045730: , HPA059094: " SPANXN5 "CT11.10, SPANX-N5" ENSG00000204363 "SPANX family member N5" Q5MJ07 X 52796144-52797427 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 279 "testis: 38.2" "Group enriched" "Detected in some" 82 "Early spermatids: 347.1;Late primary spermatocytes: 163.8;Late spermatids: 111.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 72: Neuronal - Signal transduction" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" SPARC "BM-40, ON, ONT" ENSG00000113140 "Secreted protein acidic and cysteine rich" P09486 5 151661096-151686975 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 1465.6;Endometrial stromal cells: 974.4;Extravillous trophoblasts: 545.5;Fibroblasts: 758.8;Hepatic stellate cells: 3982.6;Pericytes: 992.1;Peritubular myoid cells: 1057.7;Platelets: 2263.9;Schwann cells: 949.4;Vascular endothelial cells: 595.8" "Cell type enhanced" "Detected in many" "pericyte: 516.5;vascular associated smooth muscle cell: 321.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 10.4;classical monocyte: 8.7;neutrophil: 24.5" "Group enriched" "Detected in many" 7 "granulocytes: 24.5;monocytes: 8.7" "Cancer enhanced" "Detected in all" "Brain cancer: 2731.8" "Colon - Enteric glia cells, Pituitary gland - Fibroblasts, Prostate - Fibroblasts, Skin - Fibroblasts_1, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002306, HPA002989, HPA003020" Supported Approved Vesicles "Secreted to blood" "No annotated function" NA NA 8300000 260000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 44: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 3 Vesicles "CAB002306: , HPA002989: , HPA003020: " "unprognostic (1.43e-2)" "unprognostic (9.00e-2)" "unprognostic (2.40e-1)" "unprognostic (1.53e-2)" "unprognostic (1.78e-2)" "unprognostic (8.99e-2)" "unprognostic (1.83e-1)" "potential prognostic unfavorable (9.49e-4)" "unprognostic (2.46e-1)" "unprognostic (3.99e-3)" "potential prognostic favorable (7.66e-6)" "unprognostic (1.77e-2)" "unprognostic (2.49e-2)" "unprognostic (4.38e-2)" "unprognostic (4.32e-1)" "unprognostic (8.02e-2)" "unprognostic (1.34e-2)" "unprognostic (1.35e-2)" "unprognostic (2.50e-1)" "unprognostic (2.92e-3)" "potential prognostic unfavorable (9.49e-5)" "unprognostic (5.90e-2)" "unprognostic (1.02e-1)" "unprognostic (2.07e-1)" "unprognostic (7.62e-2)" "unprognostic (2.28e-3)" "unprognostic (7.16e-2)" "potential prognostic unfavorable (7.51e-4)" "unprognostic (1.85e-1)" "unprognostic (8.01e-2)" "unprognostic (2.05e-1)" SPARCL1 MAST9 ENSG00000152583 "SPARC like 1" Q14515 4 87473335-87531061 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 1513.6;Decidual stromal cells: 2653.5;Fibroblasts: 1548.2;Myosatellite cells: 1210.2;Pericytes: 2485.9;Peritubular myoid cells: 2437.5;Pituicytes/FSCs: 1039.1;Smooth muscle cells: 1882.3;Vascular endothelial cells: 3262.3;Vascular smooth muscle cells: 4427.3" "Cell type enhanced" "Detected in all" "astrocyte: 1412.7" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 1092.8;Kidney Chromophobe (TCGA): 761.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "Rhabdoid: 118.1" "Adrenal gland - Fibroblasts, Breast - Endothelial cells, Prostate - Smooth muscle cells, Skeletal muscle - Endothelial cells, Spleen - Fibroblasts_2, Stomach - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB026225 Approved "Secreted in other tissues" "No annotated function" NA NA 220000000 "Cluster 74: Non-specific - Signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 62: Smooth muscle cells - Muscle contraction" 1 "CAB026225: " "unprognostic (4.80e-2)" "unprognostic (6.28e-2)" "unprognostic (3.30e-2)" "unprognostic (8.70e-2)" "unprognostic (1.93e-2)" "unprognostic (1.69e-2)" "unprognostic (1.44e-1)" "unprognostic (1.72e-2)" "unprognostic (5.51e-2)" "unprognostic (7.86e-2)" "potential prognostic favorable (3.48e-6)" "unprognostic (7.22e-3)" "unprognostic (1.34e-3)" "unprognostic (2.11e-3)" "unprognostic (4.05e-3)" "unprognostic (2.71e-3)" "unprognostic (2.62e-1)" "unprognostic (4.67e-2)" "unprognostic (2.60e-1)" "unprognostic (3.64e-2)" "unprognostic (5.14e-3)" "unprognostic (3.10e-1)" "unprognostic (9.40e-2)" "unprognostic (1.47e-1)" "unprognostic (1.01e-2)" "unprognostic (2.10e-1)" "unprognostic (1.74e-2)" "unprognostic (2.41e-3)" "unprognostic (7.36e-2)" "unprognostic (5.52e-3)" "unprognostic (1.45e-1)" SPART "KIAA0610, SPG20, TAHCCP1" ENSG00000133104 Spartin Q8N0X7 13 36301638-36370180 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism, Lipid transport, Transport" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "basophil: 173.2" "Lineage enriched" "Detected in all" 7 "granulocytes: 173.2" "Low cancer specificity" "Detected in many" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039053, HPA039054" Approved Supported Cytosol NA NA "Cluster 41: Basophils - Unknown function" "Cluster 65: Brain - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 7: Non-specific - Transcription" 25 Cytosol "HPA039053: , HPA039054: " "unprognostic (2.80e-1)" "unprognostic (1.89e-1)" "unprognostic (2.69e-1)" "unprognostic (3.89e-2)" "unprognostic (1.27e-2)" "unprognostic (8.94e-3)" "unprognostic (5.00e-1)" "unprognostic (1.35e-1)" "unprognostic (8.11e-2)" "validated prognostic favorable (1.11e-8)" "validated prognostic favorable (9.88e-4)" "unprognostic (1.41e-1)" "unprognostic (9.19e-3)" "unprognostic (3.64e-1)" "unprognostic (2.33e-2)" "unprognostic (3.27e-1)" "unprognostic (1.65e-1)" "unprognostic (1.65e-1)" "unprognostic (6.83e-3)" "unprognostic (1.12e-1)" "potential prognostic unfavorable (5.76e-4)" "unprognostic (5.39e-2)" "unprognostic (1.06e-1)" "unprognostic (9.68e-2)" "unprognostic (4.47e-2)" "unprognostic (1.18e-1)" "unprognostic (1.29e-1)" "unprognostic (4.68e-2)" "unprognostic (1.87e-1)" SPAST "ADPSP, FSP2, KIAA1083, SPG4" ENSG00000021574 Spastin Q9UBP0 2 32063556-32157637 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell cycle, Cell division, Differentiation, Neurogenesis" "Allosteric enzyme, Developmental protein, Isomerase" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 161.5;Neutrophils: 212.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017311 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 24: Neutrophils - Innate immunity signal integration" 17 Nucleoplasm Cytosol "HPA017311: " "unprognostic (1.29e-1)" "unprognostic (8.67e-2)" "unprognostic (2.42e-1)" "unprognostic (3.36e-1)" "unprognostic (1.93e-1)" "unprognostic (7.51e-3)" "unprognostic (3.96e-2)" "unprognostic (1.87e-2)" "unprognostic (1.11e-1)" "unprognostic (4.55e-2)" "unprognostic (1.94e-2)" "unprognostic (4.68e-1)" "unprognostic (3.87e-3)" "validated prognostic unfavorable (3.71e-4)" "validated prognostic unfavorable (3.10e-4)" "unprognostic (1.52e-1)" "unprognostic (4.05e-2)" "unprognostic (3.30e-3)" "unprognostic (2.90e-3)" "unprognostic (2.15e-1)" "unprognostic (2.16e-2)" "unprognostic (2.29e-1)" "unprognostic (1.33e-2)" "unprognostic (4.16e-1)" "unprognostic (4.04e-2)" "unprognostic (7.03e-2)" "unprognostic (1.35e-1)" "unprognostic (3.32e-2)" "unprognostic (2.97e-1)" "unprognostic (1.64e-2)" "unprognostic (1.26e-1)" SPATA1 SP-2 ENSG00000122432 "Spermatogenesis associated 1" 1 84506300-84567379 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "testis: 1.0" "Cell type enhanced" "Detected in many" "Adipocytes: 117.9;Cardiomyocytes: 250.7;Early spermatids: 90.6;Epicardial cells: 81.9;Pituicytes/FSCs: 94.3" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in some" 4 "Prostate Adenocarcinoma (TCGA): 8.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA054300 Approved "Plasma membrane,Cytosol" NA NA "Cluster 39: Testis - Nuclear processes" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "Plasma membrane, Cytosol" "HPA054300: " "unprognostic (2.74e-1)" "unprognostic (3.14e-1)" "potential prognostic favorable (7.63e-4)" "unprognostic (8.21e-2)" "unprognostic (2.11e-1)" "unprognostic (1.98e-1)" SPATA12 ENSG00000186451 "Spermatogenesis associated 12" Q7Z6I5 3 57060664-57075432 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 57 "testis: 21.4" "Group enriched" "Detected in many" 39 "Early spermatids: 677.7;Late spermatids: 1849.0" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 7.2;endothelial cell: 3.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "HPA043323, HPA075578" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" No No "Cluster 23: Testis - Spermatogenesis" "Cluster 8: Immune cells - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 22 "Nucleoplasm, Cytosol" "Plasma membrane" "HPA043323: , HPA075578: " "unprognostic (2.74e-1)" "unprognostic (3.22e-2)" "unprognostic (1.78e-2)" "unprognostic (3.98e-2)" SPATA13 "ARHGEF29, ASEF2, FLJ31208" ENSG00000182957 "Spermatogenesis associated 13" Q96N96 13 23979805-24307074 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 61.5" "Cell type enhanced" "Detected in many" "Astrocytes: 138.8;Bergmann glia: 192.7;Brain inhibitory neurons: 137.3;Choroid plexus epithelial cells: 781.0;Ependymal cells: 410.8;Microglia: 241.5;Oligodendrocytes: 251.3" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 535.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Prostate - Prostate glandular cells, Spleen - Endothelial cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040185, HPA041208" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 11: White matter - Signal transduction" "Cluster 19: Non-specific - Unknown function" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 2 Nucleoplasm Cytosol "HPA040185: , HPA041208: " "unprognostic (7.65e-2)" "unprognostic (1.67e-1)" "unprognostic (2.48e-1)" "unprognostic (2.40e-1)" "unprognostic (8.46e-2)" "unprognostic (1.78e-1)" "unprognostic (1.35e-1)" "unprognostic (2.19e-1)" "unprognostic (5.45e-3)" "unprognostic (2.41e-1)" "potential prognostic favorable (1.43e-4)" "unprognostic (2.09e-2)" "unprognostic (5.30e-2)" "unprognostic (7.94e-2)" "unprognostic (2.49e-1)" "unprognostic (1.10e-2)" "unprognostic (1.42e-1)" "unprognostic (1.35e-1)" "unprognostic (2.20e-1)" "unprognostic (1.09e-1)" "unprognostic (6.95e-2)" "unprognostic (3.10e-1)" "unprognostic (9.08e-2)" "unprognostic (1.22e-1)" "unprognostic (2.03e-1)" "unprognostic (6.00e-3)" "unprognostic (3.40e-1)" "unprognostic (1.26e-2)" "unprognostic (7.16e-2)" "unprognostic (1.10e-1)" "unprognostic (9.02e-2)" SPATA16 NYD-SP12 ENSG00000144962 "Spermatogenesis associated 16" Q9BXB7 3 172889357-173141235 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 556 "testis: 55.6" "Group enriched" "Detected in some" 7 "Early spermatids: 247.3;Late primary spermatocytes: 592.3;Late spermatids: 179.5" "Cell type enhanced" "Detected in some" "deep-layer near-projecting: 5.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA037884 Enhanced NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 50: Lymphoma - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" "HPA037884: " SPATA17 "CFAP305, FAP305, IQCH, MOT17" ENSG00000162814 "Spermatogenesis associated 17" Q96L03 1 217631324-217871696 "Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 9.5" "Group enriched" "Detected in many" 5 "Choroid plexus epithelial cells: 584.8;Early spermatids: 819.9;Endometrial ciliated cells: 413.6;Ependymal cells: 1025.4;Epididymal efferent duct ciliated cells: 316.5;Fallopian tube ciliated cells: 496.0;Late primary spermatocytes: 1029.0;Late spermatids: 745.8;Respiratory ciliated cells: 717.8" "Group enriched" "Detected in all" 17 "choroid plexus epithelial cell: 448.7;ependymal cell: 1122.7" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA030099 Enhanced Uncertain Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" 5 "Nucleoplasm, Nucleoli, Cytosol" "HPA030099: " "unprognostic (8.92e-2)" "unprognostic (1.25e-1)" "unprognostic (1.15e-2)" "unprognostic (2.48e-1)" "unprognostic (7.92e-3)" "unprognostic (4.38e-2)" "unprognostic (1.37e-1)" SPATA18 FLJ32906 ENSG00000163071 "Spermatogenesis associated 18" Q8TC71 4 52051304-52097299 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 64.3;testis: 27.5" "Cell type enriched" "Detected in many" 5 "Late spermatids: 3633.7" "Group enriched" "Detected in many" 5 "choroid plexus epithelial cell: 71.4;ependymal cell: 254.1" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 16.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 7.0;testis cancer: 8.9" "Lung - Respiratory ciliated cells, Skeletal muscle - Fibroblasts, Testis - Late spermatids" "Low region specificity" "Detected in many" "Region enhanced" "Detected in all" "midbrain: 22.2" "HPA036854, HPA036855" Enhanced Supported Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 40: Non-specific - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 17 Mitochondria "Nucleoplasm, Cytosol" "HPA036854: , HPA036855: " "unprognostic (1.23e-1)" "unprognostic (6.78e-2)" "unprognostic (2.93e-1)" "unprognostic (7.60e-2)" "unprognostic (1.29e-3)" "unprognostic (2.95e-2)" "unprognostic (3.21e-3)" "unprognostic (3.12e-2)" "unprognostic (2.01e-2)" "unprognostic (1.19e-3)" "potential prognostic favorable (5.14e-14)" "unprognostic (1.39e-3)" "potential prognostic favorable (7.31e-12)" "unprognostic (1.18e-1)" "potential prognostic favorable (5.39e-6)" "unprognostic (1.67e-2)" "unprognostic (1.66e-1)" "unprognostic (1.52e-1)" "unprognostic (3.58e-1)" "unprognostic (1.36e-1)" "unprognostic (7.57e-2)" "unprognostic (2.07e-1)" "unprognostic (5.12e-2)" "unprognostic (1.35e-1)" "unprognostic (2.71e-2)" "unprognostic (1.14e-1)" "unprognostic (6.03e-2)" "unprognostic (3.54e-1)" "unprognostic (1.28e-1)" "unprognostic (7.32e-3)" "unprognostic (2.21e-2)" SPATA19 "CT132, FLJ25851, SPAS1, spergen1" ENSG00000166118 "Spermatogenesis associated 19" Q7Z5L4 11 133840631-133845538 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 465 "testis: 125.4" "Group enriched" "Detected in some" 12 "Early spermatids: 937.7;Late spermatids: 3139.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA040082 Enhanced NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" "HPA040082: " SPATA2 "KIAA0757, PD1, PPP1R145, tamo" ENSG00000158480 "Spermatogenesis associated 2" Q9UM82 20 49903391-49915529 "Predicted intracellular proteins" Necrosis "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 38.9;Late primary spermatocytes: 84.3;Late spermatids: 94.7;Syncytiotrophoblasts: 40.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pituitary gland - Corticotropes, Spleen - Endothelial cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048581, HPA052224" Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center" No No "Cluster 33: Non-specific - ATP binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 62: Non-specific - Plasma proteins" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 32 "Nucleoli fibrillar center" Nucleoplasm "HPA048581: , HPA052224: " "unprognostic (1.66e-2)" "unprognostic (3.41e-2)" "unprognostic (3.65e-2)" "unprognostic (1.40e-1)" "unprognostic (3.22e-2)" "unprognostic (8.40e-2)" "unprognostic (1.89e-1)" "unprognostic (6.80e-2)" "unprognostic (1.28e-1)" "unprognostic (8.50e-2)" "unprognostic (1.35e-3)" "unprognostic (1.07e-1)" "unprognostic (3.03e-1)" "potential prognostic unfavorable (8.78e-4)" "unprognostic (2.13e-3)" "unprognostic (3.48e-1)" "unprognostic (3.88e-2)" "unprognostic (1.33e-2)" "unprognostic (4.56e-2)" "unprognostic (4.96e-2)" "unprognostic (3.12e-2)" "unprognostic (4.19e-2)" "unprognostic (1.40e-2)" "unprognostic (1.70e-1)" "unprognostic (2.08e-3)" "unprognostic (1.47e-1)" "unprognostic (1.04e-1)" "unprognostic (3.69e-2)" "unprognostic (1.78e-1)" "potential prognostic unfavorable (1.13e-4)" "unprognostic (1.35e-1)" SPATA20 "FLJ21347, SSP411, Tisp78" ENSG00000006282 "Spermatogenesis associated 20" Q8TB22 17 50543058-50555852 "Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 112.8" "Group enriched" "Detected in many" 8 "Early spermatids: 663.1;Late spermatids: 2405.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Stomach - Gastric mucous cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA027144, HPA031442" Enhanced Approved "Principal piece" "Secreted in male reproductive system" "Developmental protein" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 1 "Principal piece" "HPA027144: , HPA031442: " "unprognostic (5.49e-2)" "unprognostic (8.45e-2)" "unprognostic (1.81e-1)" "unprognostic (1.72e-1)" "unprognostic (2.97e-1)" "unprognostic (1.64e-2)" "unprognostic (8.37e-2)" "unprognostic (1.18e-2)" "unprognostic (1.78e-2)" "unprognostic (2.57e-1)" "unprognostic (3.29e-1)" "unprognostic (1.30e-1)" "unprognostic (2.47e-2)" "unprognostic (3.54e-2)" "unprognostic (4.91e-2)" "unprognostic (3.30e-1)" "unprognostic (2.43e-1)" "unprognostic (6.63e-2)" "unprognostic (1.24e-1)" "unprognostic (9.75e-2)" "unprognostic (8.94e-2)" "unprognostic (4.13e-2)" "unprognostic (8.49e-2)" "unprognostic (2.79e-1)" "unprognostic (4.91e-2)" "unprognostic (1.27e-1)" "unprognostic (2.02e-2)" "unprognostic (6.42e-2)" "unprognostic (2.37e-1)" "unprognostic (1.68e-1)" "unprognostic (1.72e-1)" SPATA21 "spergen-2, spergen2" ENSG00000187144 "Spermatogenesis associated 21" Q7Z572 1 16387117-16437424 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 9 "testis: 7.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 57.8;Early spermatids: 109.3;Epicardial cells: 122.8;Late primary spermatocytes: 57.4;Late spermatids: 66.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.7" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.7" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA032080 Approved Vesicles,Cytosol No NA "Cluster 46: Basophils - Proteolysis" "Cluster 57: Testis - Spermatogenesis" "Cluster 48: Non-specific - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" "Vesicles, Cytosol" "HPA032080: " "unprognostic (5.64e-2)" "unprognostic (4.21e-1)" "unprognostic (3.41e-3)" "unprognostic (1.42e-2)" "unprognostic (1.62e-1)" SPATA22 NYD-SP20 ENSG00000141255 "Spermatogenesis associated 22" Q8NHS9 17 3440019-3513852 "Predicted intracellular proteins" Meiosis "Disease variant, Premature ovarian failure" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 64 "testis: 215.0" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 482.7;Early spermatids: 154.1;Fibro-adipogenic progenitors: 79.2;Late primary spermatocytes: 996.0;Late spermatids: 192.3;Myonuclei: 73.3;Oligodendrocytes: 86.6" "Cell type enhanced" "Detected in all" "oligodendrocyte: 121.8" "Cancer enriched" "Detected in some" 9 "Testicular Germ Cell Tumor (TCGA): 12.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 2.2;Neuroblastoma: 2.9" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 16 "unprognostic (1.40e-1)" "unprognostic (1.55e-1)" "unprognostic (3.79e-1)" SPATA24 "CCDC161, T6441" ENSG00000170469 "Spermatogenesis associated 24" Q86W54 5 139396563-139404089 "Predicted intracellular proteins" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "testis: 138.6" "Group enriched" "Detected in many" 8 "Early spermatids: 1278.6;Late spermatids: 3994.5" "Cell type enhanced" "Detected in many" "ependymal cell: 18.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044000 Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 79: Testis - Spermatogenesis" "Cluster 46: Brainstem - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 9 "Nucleoplasm, Cytosol" "HPA044000: " "unprognostic (6.54e-3)" "unprognostic (1.36e-2)" "unprognostic (8.71e-2)" "unprognostic (8.19e-2)" "unprognostic (6.44e-3)" "unprognostic (6.29e-2)" "unprognostic (1.40e-1)" "unprognostic (1.07e-1)" "unprognostic (2.82e-1)" "unprognostic (1.23e-3)" "potential prognostic favorable (4.81e-5)" "unprognostic (7.94e-3)" "potential prognostic favorable (2.16e-4)" "potential prognostic unfavorable (2.59e-6)" "unprognostic (2.47e-2)" "unprognostic (2.52e-1)" "unprognostic (2.30e-1)" "unprognostic (3.19e-1)" "unprognostic (7.64e-2)" "unprognostic (1.89e-2)" "unprognostic (3.38e-3)" "unprognostic (7.94e-3)" "unprognostic (2.36e-1)" "unprognostic (2.17e-1)" "unprognostic (4.20e-2)" "unprognostic (2.16e-3)" "unprognostic (2.93e-3)" "unprognostic (2.52e-2)" "unprognostic (2.52e-1)" "unprognostic (1.45e-1)" "unprognostic (6.13e-2)" SPATA25 "C20orf165, dJ337O18.8, TSG23" ENSG00000149634 "Spermatogenesis associated 25" Q9BR10 20 45886491-45887622 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 22.9" "Cell type enhanced" "Detected in some" "Early spermatids: 369.6;Late primary spermatocytes: 131.9;Late spermatids: 69.4" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA041386 Approved "Golgi apparatus" NA NA "Cluster 47: Testis - Mixed function" "Cluster 25: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" "Golgi apparatus" "HPA041386: " "unprognostic (1.04e-1)" "unprognostic (1.84e-1)" "unprognostic (5.95e-2)" "unprognostic (1.06e-1)" "unprognostic (7.56e-2)" "unprognostic (5.74e-3)" "unprognostic (2.19e-1)" "unprognostic (1.13e-2)" "unprognostic (1.43e-2)" "unprognostic (1.02e-2)" "unprognostic (1.04e-3)" "unprognostic (9.50e-2)" "unprognostic (1.09e-1)" "unprognostic (2.78e-1)" "unprognostic (3.57e-2)" "unprognostic (3.28e-1)" "unprognostic (1.52e-3)" "unprognostic (5.10e-3)" "unprognostic (1.72e-2)" "potential prognostic favorable (1.69e-5)" "unprognostic (8.24e-3)" "unprognostic (1.27e-1)" "unprognostic (4.61e-2)" "potential prognostic unfavorable (3.60e-5)" SPATA2L "C16orf76, MGC26885, tamo" ENSG00000158792 "Spermatogenesis associated 2 like" Q8IUW3 16 89696357-89701705 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Enterocytes: 49.6;Neutrophils: 57.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Minor salivary glandular cells, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041182, HPA042453" Uncertain Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 70: Non-specific - Protein processing" "Cluster 51: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 19 "Nucleoplasm, Mitochondria" Cytosol "HPA041182: , HPA042453: " "unprognostic (1.01e-1)" "unprognostic (1.93e-1)" "unprognostic (6.77e-2)" "unprognostic (1.00e-1)" "unprognostic (7.79e-2)" "unprognostic (5.75e-2)" "unprognostic (3.06e-1)" "unprognostic (2.86e-1)" "unprognostic (1.82e-2)" "unprognostic (1.14e-2)" "unprognostic (5.49e-3)" "unprognostic (2.50e-2)" "unprognostic (2.89e-2)" "unprognostic (7.03e-3)" "unprognostic (3.23e-2)" "unprognostic (1.67e-1)" "unprognostic (1.05e-1)" "unprognostic (1.73e-1)" "unprognostic (6.79e-2)" "unprognostic (1.01e-1)" "unprognostic (6.45e-2)" "unprognostic (1.49e-3)" "unprognostic (2.10e-1)" "unprognostic (1.03e-1)" "unprognostic (4.36e-2)" "unprognostic (1.58e-1)" "unprognostic (4.62e-1)" "unprognostic (6.19e-2)" "unprognostic (1.62e-1)" "unprognostic (1.26e-1)" "unprognostic (6.82e-2)" SPATA3 TSARG1 ENSG00000173699 "Spermatogenesis associated 3" Q8NHX4 2 230990324-231025055 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 490 "testis: 169.4" "Cell type enriched" "Detected in some" 9 "Late spermatids: 10406.2" "Cell type enhanced" "Detected in some" "astrocyte: 3.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Low region specificity" "Detected in many" "Region enriched" "Detected in single" 14 "cerebellum: 4.9" HPA018254 Enhanced NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 6: Non-specific - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" "HPA018254: " SPATA31A1 "C9orf36, C9orf36A, DKFZP434B204, FAM75A1, FAM75A2, SPATA31A2" ENSG00000204849 "SPATA31 subfamily A member 1" Q5TZJ5 9 39355669-39361962 "Predicted membrane proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 85 "testis: 8.4" "Group enriched" "Detected in some" 7 "Early spermatids: 15.7;Late primary spermatocytes: 10.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" HPA051472 Approved "Acrosome,Equatorial segment" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 66: Non-specific - Mitochondria" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" "Acrosome, Equatorial segment" "HPA051472: " SPATA31A3 "DKFZp434B204, FAM75A3" ENSG00000275969 "SPATA31 subfamily A member 3" Q5VYP0 9 66986304-66992550 "Predicted membrane proteins" "Differentiation, Spermatogenesis" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 44 "testis: 4.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" HPA051472 Approved "Acrosome,Equatorial segment" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 66: Non-specific - Mitochondria" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" "Acrosome, Equatorial segment" "HPA051472: " SPATA31A5 FAM75A5 ENSG00000276581 "SPATA31 subfamily A member 5" Q5VU36 9 60914407-60920653 "Predicted membrane proteins" "Differentiation, Spermatogenesis" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 14 "testis: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA051472 Approved "Acrosome,Equatorial segment" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 66: Non-specific - Mitochondria" "Acrosome, Equatorial segment" "HPA051472: " SPATA31A6 FAM75A6 ENSG00000185775 "SPATA31 subfamily A member 6" Q5VVP1 9 42183659-42189887 "Essential proteins, Predicted membrane proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 19 "testis: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA051472 Approved "Acrosome,Equatorial segment" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 66: Non-specific - Mitochondria" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" "Acrosome, Equatorial segment" "HPA051472: " SPATA31A7 "FAM75A4, FAM75A7, SPATA31A4" ENSG00000276040 "SPATA31 subfamily A member 7" Q8IWB4 9 61190036-61196280 "Predicted membrane proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 25 "testis: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA051472 Approved "Acrosome,Equatorial segment" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 66: Non-specific - Mitochondria" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 3 "Acrosome, Equatorial segment" "HPA051472: " SPATA31C1 "FAM75C1, FLJ36055" ENSG00000230246 "SPATA31 subfamily C member 1" P0DKV0 9 87914488-87923657 "Predicted membrane proteins" "Differentiation, Spermatogenesis" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "testis: 6.9" "Cell type enhanced" "Detected in some" "Early spermatids: 46.5;Late primary spermatocytes: 18.4;Late spermatids: 11.2" "Not detected" "Not detected" "Region enriched" "Detected in some" 7 "hippocampal formation: 14.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 29: Forebrain - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" SPATA31C2 "DKFZP434M131, FAM75C2" ENSG00000177910 "SPATA31 subfamily C member 2" B4DYI2 9 88129305-88138475 "Predicted membrane proteins" "Differentiation, Spermatogenesis" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 71 "epididymis: 21.7;testis: 7.3" "Cell type enhanced" "Detected in some" "Early spermatids: 34.8;Epididymal principal cells: 5.9;Late primary spermatocytes: 15.8;Late spermatids: 6.7" "Not detected" "Not detected" "Region enriched" "Detected in some" 12 "hippocampal formation: 13.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Myeloma: 1.1" "Testis - Early spermatids, Testis - Late spermatids" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 22: Epididymis - Mixed function" "Cluster 29: Forebrain - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" SPATA31D1 "FAM75D1, FLJ46321" ENSG00000214929 "SPATA31 subfamily D member 1" Q6ZQQ2 9 81988772-81995253 "Predicted membrane proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 107 "testis: 10.7" "Cell type enhanced" "Detected in single" "Early spermatids: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" HPA047897 Uncertain NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" "HPA047897: " SPATA31D3 "FAM75D3, FLJ44082" ENSG00000186788 "SPATA31 subfamily D member 3" P0C874 9 81943500-81950093 "Predicted membrane proteins" "Differentiation, Spermatogenesis" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 77 "testis: 7.6" "Cell type enriched" "Detected in some" 8 "Early spermatids: 38.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" SPATA31D4 "FAM75D4, FLJ43859" ENSG00000189357 "SPATA31 subfamily D member 4" Q6ZUB0 9 81928428-81934998 "Predicted membrane proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 58 "testis: 5.8" "Cell type enriched" "Detected in some" 8 "Early spermatids: 34.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" SPATA31E1 "C9orf79, FAM75E1, FLJ35866" ENSG00000177992 "SPATA31 subfamily E member 1" Q6ZUB1 9 87882877-87888903 "Predicted membrane proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 72 "testis: 7.1" "Group enriched" "Detected in some" 16 "Early spermatids: 66.5;Late spermatids: 20.7" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in some" 12 "hippocampal formation: 15.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA024253 Enhanced NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 29: Forebrain - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 1 "HPA024253: " SPATA32 "AEP2, C17orf46, FLJ25414, TEX34, VAD1.2" ENSG00000184361 "Spermatogenesis associated 32" Q96LK8 17 45254393-45262094 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 80 "testis: 43.5" "Group enriched" "Detected in many" 21 "Early spermatids: 388.2;Late spermatids: 1395.9" "Cell type enhanced" "Detected in some" "leukocyte: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA024549 Approved NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 4: Non-specific - Transcription" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 2 "HPA024549: " SPATA33 "C16orf55, FLJ31606" ENSG00000167523 "Spermatogenesis associated 33" Q96N06 16 89657740-89671272 "Predicted intracellular proteins" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "testis: 86.5" "Cell type enhanced" "Detected in many" "Early spermatids: 1888.7;Late primary spermatocytes: 1101.7;Late spermatids: 5815.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Late spermatids" "HPA045648, HPA073096" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 3 Nucleoplasm Vesicles "HPA045648: , HPA073096: " "unprognostic (2.80e-1)" "unprognostic (2.40e-1)" "unprognostic (3.18e-3)" "unprognostic (3.03e-3)" "unprognostic (1.02e-1)" "unprognostic (1.90e-1)" "unprognostic (9.29e-2)" "unprognostic (1.64e-1)" "unprognostic (2.67e-2)" "unprognostic (8.90e-2)" "unprognostic (4.47e-1)" "potential prognostic favorable (3.85e-4)" "potential prognostic unfavorable (7.18e-4)" "unprognostic (8.04e-2)" "unprognostic (1.12e-1)" "unprognostic (2.46e-1)" "unprognostic (3.09e-1)" "unprognostic (2.56e-1)" "unprognostic (7.56e-2)" "unprognostic (1.72e-3)" "unprognostic (6.60e-2)" "unprognostic (3.82e-1)" "unprognostic (1.44e-1)" "unprognostic (1.21e-1)" "unprognostic (3.47e-2)" "unprognostic (8.52e-2)" "unprognostic (1.62e-1)" "unprognostic (5.60e-2)" "unprognostic (5.49e-2)" SPATA4 "CFAP178, FAP178, SPEF1B, TSARG2" ENSG00000150628 "Spermatogenesis associated 4" Q8NEY3 4 176184579-176195585 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "testis: 130.4" "Group enriched" "Detected in many" 10 "Early spermatids: 1012.4;Late primary spermatocytes: 1446.1;Late spermatids: 643.9" "Cell type enriched" "Detected in many" 6 "ependymal cell: 36.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "basophil: 1.2" "Lineage enriched" "Detected in single" 9 "granulocytes: 1.2" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA019220, HPA030791" Enhanced Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 32: Basophils - Transcription" "Cluster 57: Testis - Spermatogenesis" "Cluster 17: Choroid plexus - Cilium" "Cluster 72: Neuronal - Signal transduction" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 2 Nucleoplasm "Vesicles, Cytosol" "HPA019220: , HPA030791: " "unprognostic (2.17e-1)" "unprognostic (2.71e-3)" "unprognostic (1.44e-2)" "potential prognostic favorable (2.35e-6)" "unprognostic (3.89e-2)" "potential prognostic favorable (8.14e-4)" SPATA45 "C1orf227, LOC149643" ENSG00000185523 "Spermatogenesis associated 45" Q537H7 1 212830141-212847649 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "testis: 11.5" "Group enriched" "Detected in some" 6 "Early spermatids: 161.8;Late primary spermatocytes: 70.4;Late spermatids: 186.8" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "eosinophil: 1.6" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA049921 Uncertain Uncertain "Nuclear speckles,Cytosol" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" "Nuclear speckles, Cytosol" "HPA049921: " "unprognostic (3.05e-1)" SPATA46 "C1orf111, TEKT2BP2" ENSG00000171722 "Spermatogenesis associated 46" Q5T0L3 1 162373203-162376854 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "testis: 29.7" "Group enriched" "Detected in some" 52 "Early spermatids: 819.2;Late primary spermatocytes: 375.5;Late spermatids: 239.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adrenal gland - Adrenal medulla cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 14: Neurons - Synaptic function" "Cluster 1: Neuronal - Visual perception" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 23 "unprognostic (8.71e-2)" SPATA48 C7orf72 ENSG00000164500 "Spermatogenesis associated 48" A4D263 7 50095883-50159256 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 9 "testis: 4.1" "Group enriched" "Detected in some" 24 "Early spermatids: 61.2;Late primary spermatocytes: 87.1;Late spermatids: 37.0" "Cell type enhanced" "Detected in some" "LAMP5-LHX6 and Chandelier: 7.8;MGE interneuron: 4.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lymphoma: 1.7" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA026094 Uncertain Approved "Connecting piece,Mid piece,Principal piece" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 35: RS4;11 - Unknown function" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" "Connecting piece, Mid piece, Principal piece" "HPA026094: " SPATA5 "AFG2, SPAF" ENSG00000145375 "Spermatogenesis associated 5" Q8NB90 4 122923070-123319433 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Differentiation, Ribosome biogenesis, Spermatogenesis" "Chaperone, Developmental protein, Hydrolase" "Deafness, Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036450, HPA036451" Approved Approved Cytosol NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 39: Testis - Nuclear processes" "Cluster 25: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 7: Non-specific - Transcription" 15 Cytosol "HPA036450: , HPA036451: " "unprognostic (7.69e-2)" "unprognostic (3.80e-2)" "unprognostic (1.00e-1)" "unprognostic (3.52e-2)" "unprognostic (1.27e-1)" "unprognostic (1.55e-3)" "unprognostic (3.05e-1)" "unprognostic (6.62e-2)" "unprognostic (2.70e-1)" "potential prognostic unfavorable (2.01e-4)" "unprognostic (4.15e-3)" "potential prognostic favorable (5.80e-4)" "unprognostic (1.46e-1)" "unprognostic (1.11e-2)" "unprognostic (2.21e-3)" "unprognostic (7.47e-2)" "unprognostic (1.69e-1)" "unprognostic (1.19e-1)" "unprognostic (7.49e-3)" "unprognostic (1.23e-3)" "unprognostic (2.43e-3)" "unprognostic (2.27e-2)" "unprognostic (1.05e-2)" "potential prognostic favorable (6.88e-4)" "unprognostic (2.76e-2)" "unprognostic (8.79e-2)" "unprognostic (2.33e-1)" "unprognostic (1.34e-2)" "unprognostic (1.19e-1)" SPATA5L1 "FLJ12286, MGC5347" ENSG00000171763 "Spermatogenesis associated 5 like 1" Q9BVQ7 15 45402336-45421415 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Ribosome biogenesis" Hydrolase "Deafness, Epilepsy, Intellectual disability, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 86.0;Neutrophils: 64.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043679 Uncertain Approved Nucleoplasm,Nucleoli NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 29 Nucleoplasm Nucleoli "HPA043679: " "unprognostic (2.36e-2)" "unprognostic (2.50e-3)" "unprognostic (2.75e-1)" "unprognostic (2.33e-1)" "unprognostic (5.39e-2)" "unprognostic (3.70e-1)" "unprognostic (9.76e-2)" "unprognostic (3.70e-3)" "potential prognostic unfavorable (8.74e-4)" "unprognostic (1.38e-1)" "unprognostic (2.39e-2)" "unprognostic (4.42e-2)" "unprognostic (1.48e-3)" "validated prognostic unfavorable (2.44e-4)" "validated prognostic unfavorable (2.48e-4)" "potential prognostic unfavorable (3.63e-4)" "unprognostic (7.61e-2)" "unprognostic (1.44e-2)" "unprognostic (2.35e-1)" "unprognostic (2.90e-2)" "unprognostic (2.41e-1)" "unprognostic (1.14e-2)" "unprognostic (2.05e-2)" "unprognostic (1.07e-2)" "unprognostic (5.66e-2)" "unprognostic (2.17e-2)" "unprognostic (2.17e-1)" "unprognostic (9.62e-2)" "unprognostic (1.45e-1)" "unprognostic (1.65e-1)" "unprognostic (1.49e-1)" SPATA6 "FLJ10007, SRF-1, SRF1" ENSG00000132122 "Spermatogenesis associated 6" Q9NWH7 1 48295373-48472208 "Cancer-related genes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 46.8" "Cell type enriched" "Detected in many" 4 "Late spermatids: 6642.1" "Cell type enhanced" "Detected in all" "oligodendrocyte precursor cell: 817.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 5.9" "Group enriched" "Detected in many" 4 "granulocytes: 3.6;monocytes: 5.9" "Low cancer specificity" "Detected in many" "Skin - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028234 Approved "Nucleoplasm,Golgi apparatus,Vesicles" "Intracellular and membrane" "Developmental protein" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 21: Testis - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 1 "Golgi apparatus, Vesicles" Nucleoplasm "HPA028234: " "unprognostic (1.43e-3)" "unprognostic (1.09e-1)" "unprognostic (9.78e-3)" "unprognostic (7.06e-2)" "unprognostic (2.78e-2)" "unprognostic (2.05e-1)" "unprognostic (2.82e-1)" "unprognostic (7.88e-2)" "unprognostic (6.97e-2)" "potential prognostic favorable (3.26e-7)" "unprognostic (4.86e-3)" "unprognostic (3.17e-2)" "unprognostic (8.21e-3)" "potential prognostic favorable (5.65e-5)" "unprognostic (2.53e-1)" "unprognostic (6.79e-3)" "unprognostic (2.15e-1)" "unprognostic (2.24e-1)" "unprognostic (4.06e-1)" "unprognostic (3.53e-1)" "unprognostic (5.61e-2)" "unprognostic (4.79e-2)" "unprognostic (1.96e-1)" "unprognostic (1.04e-1)" "unprognostic (1.86e-2)" "unprognostic (1.22e-1)" "unprognostic (1.09e-1)" "unprognostic (3.01e-1)" "unprognostic (3.09e-1)" SPATA6L "C9orf68, FLJ10058" ENSG00000106686 "Spermatogenesis associated 6 like" Q8N4H0 9 4553386-4666674 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 217.5;Early spermatids: 196.2;Endometrial ciliated cells: 184.8;Ependymal cells: 430.2;Fallopian tube ciliated cells: 242.1;Gonadotrophs: 189.0;Lactotrophs: 269.7;Respiratory ciliated cells: 399.5;Somatotrophs: 289.8;Thyrotrophs: 228.9" "Cell type enhanced" "Detected in all" "ependymal cell: 456.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells, Skeletal muscle - Endothelial cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039585 Enhanced NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" "HPA039585: " "unprognostic (1.84e-3)" "unprognostic (2.66e-2)" "potential prognostic unfavorable (5.76e-4)" "unprognostic (1.93e-3)" "unprognostic (2.53e-3)" "unprognostic (8.17e-2)" "unprognostic (6.21e-3)" "unprognostic (1.06e-1)" "unprognostic (5.62e-2)" "unprognostic (2.96e-1)" "unprognostic (2.13e-1)" SPATA7 "HSD3, LCA3" ENSG00000042317 "Spermatogenesis associated 7" Q9P0W8 14 88384924-88470350 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Leber congenital amaurosis, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "testis: 53.2" "Cell type enhanced" "Detected in many" "Early spermatids: 1093.6;Late primary spermatocytes: 377.5;Late spermatids: 1636.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Pituitary gland - Lactotropes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038082, HPA038083" Enhanced Supported "Vesicles,Primary cilium transition zone,Mid piece" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 21: Testis - Mixed function" "Cluster 16: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" "Vesicles, Primary cilium transition zone, Mid piece" "HPA038082: , HPA038083: " "unprognostic (2.27e-1)" "unprognostic (5.36e-2)" "unprognostic (4.88e-2)" "unprognostic (1.13e-1)" "unprognostic (2.25e-1)" "unprognostic (7.55e-2)" "unprognostic (2.65e-2)" "unprognostic (2.59e-1)" "unprognostic (1.78e-2)" "unprognostic (2.73e-1)" "potential prognostic favorable (5.85e-10)" "unprognostic (1.79e-3)" "potential prognostic favorable (2.07e-4)" "unprognostic (1.53e-2)" "potential prognostic favorable (6.21e-5)" "unprognostic (2.01e-2)" "unprognostic (1.38e-1)" "unprognostic (5.19e-2)" "unprognostic (1.47e-1)" "unprognostic (2.93e-2)" "unprognostic (9.45e-3)" "potential prognostic favorable (1.93e-4)" "unprognostic (1.75e-1)" "unprognostic (1.02e-1)" "unprognostic (3.26e-1)" "unprognostic (3.80e-2)" "unprognostic (1.09e-1)" "unprognostic (3.62e-2)" "unprognostic (3.53e-1)" "unprognostic (1.55e-1)" "unprognostic (7.79e-2)" SPATA9 "FLJ35906, NYD-SP16" ENSG00000145757 "Spermatogenesis associated 9" Q9BWV2 5 95652181-95698711 "Predicted membrane proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 22 "testis: 23.0" "Group enriched" "Detected in many" 4 "Early spermatids: 598.5;Late primary spermatocytes: 325.4;Late spermatids: 730.2" "Cell type enhanced" "Detected in many" "oligodendrocyte precursor cell: 34.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA010848, HPA076967" Approved Approved Mitochondria NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 16: Non-specific - Transcription" "Cluster 47: Leukemia - Hemostasis" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" Mitochondria "HPA010848: , HPA076967: " "unprognostic (2.28e-1)" "unprognostic (1.16e-2)" SPATC1 "MGC61633, SPATA15, SPERIOLIN" ENSG00000186583 "Spermatogenesis and centriole associated 1" Q76KD6 8 144012280-144047114 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "testis: 33.4" "Group enriched" "Detected in many" 4 "Cardiomyocytes: 206.4;Early primary spermatocytes: 311.9;Early spermatids: 180.8;Late spermatids: 674.4" "Cell type enhanced" "Detected in many" "Bergmann glia: 46.4;lower rhombic lip: 42.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Heart muscle - Cardiomyocytes, Kidney - Macrophages, Testis - Late spermatids" "Not detected" "Not detected" "Region enriched" "Detected in many" 5 "cerebellum: 12.6" NA NA "Cluster 39: Testis - Nuclear processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 3: Early primary spermatocytes - Early meiosis" 1 "potential prognostic favorable (9.70e-4)" SPATC1L C21orf56 ENSG00000160284 "Spermatogenesis and centriole associated 1 like" Q9H0A9 21 46161148-46184476 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 47.4" "Cell type enhanced" "Detected in some" "Astrocytes: 5.2;Bergmann glia: 4.0;Brain excitatory neurons: 8.5;Brain inhibitory neurons: 8.1;Choroid plexus epithelial cells: 3.7;Ependymal cells: 3.9;Late spermatids: 5.6;Microglia: 4.1;Oligodendrocyte progenitor cells: 7.6;Oligodendrocytes: 8.1;Other brain neurons: 12.2;Renal connecting tubule cells: 3.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 36.2" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA019165, HPA029394" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 67: Testis - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 98: Neurons - Neurotransmission & signaling" 9 "Plasma membrane, Cytosol" "HPA019165: , HPA029394: " "unprognostic (3.81e-1)" "unprognostic (7.67e-2)" "unprognostic (1.42e-2)" "unprognostic (3.06e-1)" "unprognostic (8.56e-2)" "unprognostic (1.66e-1)" "unprognostic (1.10e-1)" "unprognostic (2.23e-1)" "unprognostic (8.88e-2)" "potential prognostic unfavorable (1.50e-4)" "unprognostic (5.46e-2)" "unprognostic (1.76e-3)" "potential prognostic unfavorable (6.86e-4)" "unprognostic (3.14e-1)" "unprognostic (1.13e-1)" "unprognostic (1.57e-1)" "unprognostic (1.64e-1)" "unprognostic (2.01e-1)" "unprognostic (1.83e-1)" "potential prognostic favorable (1.32e-4)" "unprognostic (2.01e-1)" "unprognostic (1.01e-1)" "unprognostic (1.07e-2)" "unprognostic (4.48e-3)" "unprognostic (4.38e-2)" "unprognostic (8.52e-2)" "unprognostic (1.57e-1)" "unprognostic (6.91e-2)" "unprognostic (1.89e-1)" SPATS1 "FLJ25442, SPATA8, SRSP1" ENSG00000249481 "Spermatogenesis associated serine rich 1" Q496A3 6 44342650-44380179 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "epididymis: 5.5;fallopian tube: 7.2;testis: 20.6" "Group enriched" "Detected in some" 4 "Early spermatids: 24.6;Ependymal cells: 10.6;Late primary spermatocytes: 22.5;Late spermatids: 25.5;Respiratory ciliated cells: 7.2" "Cell type enriched" "Detected in some" 13 "ependymal cell: 14.2" "Group enriched" "Detected in some" 5 "Skin Cutaneous Melanoma (TCGA): 2.9;Testicular Germ Cell Tumor (TCGA): 1.2;Uterine Corpus Endometrial Carcinoma (TCGA): 2.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Neuroblastoma: 1.8;skin cancer: 6.8" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030897, HPA049722" Approved Approved Nucleoplasm NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 46: Brainstem - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 34: Ciliated cells - Cilia assembly & function" 17 Nucleoplasm "HPA030897: , HPA049722: " "unprognostic (1.48e-1)" "unprognostic (6.03e-2)" "unprognostic (5.67e-2)" SPATS2 "FLJ13117, SCR59, SPATA10" ENSG00000123352 "Spermatogenesis associated serine rich 2" Q86XZ4 12 49366584-49527425 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Myonuclei: 394.3;Plasma cells: 440.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 4 "B-cells: 5.9;dendritic cells: 7.8" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038642, HPA038643, HPA076823" Uncertain Enhanced Cytosol NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 44: Plasma cells - Antibody production & secretion" 27 Cytosol "HPA038642: , HPA038643: , HPA076823: " "unprognostic (2.14e-1)" "unprognostic (7.99e-3)" "unprognostic (2.32e-3)" "unprognostic (6.05e-2)" "unprognostic (1.08e-1)" "unprognostic (1.72e-2)" "unprognostic (1.96e-1)" "unprognostic (2.62e-3)" "unprognostic (6.77e-2)" "unprognostic (1.42e-2)" "unprognostic (1.66e-1)" "unprognostic (2.96e-1)" "unprognostic (9.08e-2)" "potential prognostic unfavorable (2.17e-7)" "unprognostic (1.41e-3)" "potential prognostic unfavorable (1.37e-4)" "unprognostic (7.85e-2)" "unprognostic (1.91e-1)" "unprognostic (5.34e-2)" "unprognostic (1.12e-2)" "unprognostic (1.46e-1)" "unprognostic (1.65e-1)" "unprognostic (1.96e-3)" "unprognostic (1.82e-1)" "unprognostic (7.67e-2)" "unprognostic (7.13e-2)" "potential prognostic unfavorable (8.17e-4)" "unprognostic (1.27e-1)" "unprognostic (6.93e-2)" "unprognostic (8.92e-3)" "unprognostic (1.24e-2)" SPATS2L "DNAPTP6, SGNP" ENSG00000196141 "Spermatogenesis associated serine rich 2 like" Q9NUQ6 2 200305881-200482264 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 785.7;Foveolar cells: 1143.5;Pituitary stem cells: 844.5;Urothelial cells: 906.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 47.7" "Group enriched" "Detected in all" 5 "dendritic cells: 16.8;granulocytes: 47.7;T-cells: 31.6" "Low cancer specificity" "Detected in all" "Pituitary gland - Undifferentiated cells (Pituitary gland)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055427, HPA066310" Uncertain Enhanced Nucleoli,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 60: Stomach - Digestion" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 9 "Nucleoli, Cytosol" "HPA055427: , HPA066310: " "unprognostic (4.60e-2)" "unprognostic (5.51e-2)" "unprognostic (5.97e-2)" "unprognostic (1.49e-1)" "unprognostic (1.96e-1)" "unprognostic (4.83e-1)" "unprognostic (3.34e-2)" "unprognostic (3.98e-3)" "unprognostic (4.62e-2)" "unprognostic (1.25e-3)" "potential prognostic favorable (7.26e-6)" "unprognostic (2.52e-3)" "unprognostic (8.45e-2)" "unprognostic (1.12e-3)" "unprognostic (1.05e-2)" "unprognostic (2.00e-3)" "potential prognostic unfavorable (4.95e-4)" "unprognostic (1.99e-1)" "unprognostic (1.16e-1)" "unprognostic (3.34e-1)" "unprognostic (2.72e-1)" "potential prognostic unfavorable (7.42e-4)" "unprognostic (4.81e-2)" "unprognostic (2.47e-1)" "unprognostic (2.27e-2)" "unprognostic (4.38e-2)" "unprognostic (9.61e-3)" "unprognostic (1.19e-2)" "unprognostic (2.73e-2)" "unprognostic (2.17e-1)" "potential prognostic unfavorable (2.86e-5)" SPC24 "FLJ90806, SPBC24" ENSG00000161888 "SPC24 component of NDC80 kinetochore complex" Q8NBT2 19 11131520-11155807 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 24.3;lymphoid tissue: 13.7" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 24.2;Epicardial cells: 134.2;Erythrocyte progenitors: 48.6;Hofbauer cells: 28.7;Megakaryocyte progenitors: 31.0;Monocyte progenitors: 39.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA051234 Approved Supported Nucleoplasm,Nucleoli NA Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 48: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 27: Non-specific - Cell proliferation" 38 Nucleoplasm Nucleoli "HPA051234: " "unprognostic (2.88e-2)" "unprognostic (2.51e-1)" "unprognostic (4.19e-2)" "unprognostic (3.07e-3)" "unprognostic (8.17e-2)" "unprognostic (2.52e-1)" "unprognostic (1.07e-1)" "unprognostic (9.27e-2)" "unprognostic (1.46e-2)" "potential prognostic unfavorable (3.86e-4)" "validated prognostic unfavorable (4.56e-12)" "validated prognostic unfavorable (9.67e-5)" "potential prognostic unfavorable (3.32e-7)" "validated prognostic unfavorable (6.53e-4)" "validated prognostic unfavorable (2.57e-5)" "validated prognostic unfavorable (2.76e-5)" "validated prognostic unfavorable (2.32e-4)" "unprognostic (2.67e-2)" "unprognostic (2.68e-3)" "unprognostic (8.70e-2)" "unprognostic (6.63e-2)" "unprognostic (1.99e-3)" "unprognostic (1.65e-2)" "unprognostic (4.09e-3)" "unprognostic (2.53e-1)" "unprognostic (2.15e-1)" "unprognostic (1.07e-2)" "unprognostic (6.20e-2)" "unprognostic (1.12e-1)" "unprognostic (7.30e-2)" "unprognostic (2.43e-1)" SPC25 "AD024, MGC22228, SPBC25" ENSG00000152253 "SPC25 component of NDC80 kinetochore complex" Q9HBM1 2 168834132-168913371 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 8.0" "Group enriched" "Detected in many" 4 "Oligodendrocyte progenitor cells: 65.3;Oocytes: 198.0" "Cell type enhanced" "Detected in many" "endothelial cell: 85.3;oligodendrocyte precursor cell: 68.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Colon - Mitotic cells (Colon), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA047144, HPA050544" Enhanced Enhanced Cytosol NA Yes "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 34: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 33 Cytosol "HPA047144: , HPA050544: " "unprognostic (1.19e-3)" "unprognostic (9.21e-2)" "unprognostic (5.62e-2)" "unprognostic (2.78e-1)" "unprognostic (2.37e-3)" "potential prognostic favorable (9.18e-4)" "unprognostic (1.15e-1)" "unprognostic (4.53e-3)" "unprognostic (2.00e-1)" "unprognostic (2.29e-3)" "unprognostic (1.09e-1)" "unprognostic (4.78e-2)" "validated prognostic unfavorable (2.24e-4)" "validated prognostic unfavorable (8.88e-11)" "potential prognostic unfavorable (8.65e-4)" "unprognostic (1.42e-2)" "unprognostic (1.52e-1)" "unprognostic (1.10e-1)" "unprognostic (3.16e-2)" "unprognostic (4.05e-1)" "unprognostic (3.84e-3)" "potential prognostic unfavorable (6.69e-4)" "unprognostic (4.75e-2)" "unprognostic (3.60e-1)" "unprognostic (1.51e-1)" "unprognostic (1.31e-3)" "unprognostic (1.10e-1)" "unprognostic (7.17e-2)" "unprognostic (4.78e-2)" SPCS1 "HSPC033, SPC1, SPC12, YJR010C-A" ENSG00000114902 "Signal peptidase complex subunit 1" Q9Y6A9 3 52704955-52711148 "Metabolic proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 894.3;Late primary spermatocytes: 860.6;Late spermatids: 2009.5;Plasma cells: 1111.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046091, HPA055273" Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 8: Pancreas - Proteolysis" "Cluster 21: Non-specific - Metabolism" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 67: Plasma cells - Plasma cell differentiation" 13 "Golgi apparatus, Vesicles" "HPA046091: , HPA055273: " "potential prognostic favorable (5.09e-4)" "unprognostic (8.06e-3)" "potential prognostic unfavorable (6.94e-4)" "unprognostic (4.27e-2)" "unprognostic (1.34e-2)" "unprognostic (2.25e-1)" "unprognostic (9.90e-2)" "potential prognostic unfavorable (1.69e-4)" "unprognostic (1.00e-2)" "unprognostic (2.56e-2)" "potential prognostic favorable (3.44e-4)" "unprognostic (5.86e-2)" "unprognostic (1.75e-1)" "unprognostic (2.20e-1)" "unprognostic (2.76e-2)" "unprognostic (2.80e-1)" "unprognostic (1.38e-1)" "unprognostic (1.81e-1)" "unprognostic (3.71e-1)" "unprognostic (4.79e-2)" "unprognostic (1.46e-1)" "unprognostic (1.54e-1)" "unprognostic (3.77e-1)" "unprognostic (1.11e-1)" "unprognostic (1.05e-1)" "unprognostic (1.46e-1)" "unprognostic (2.16e-1)" "unprognostic (2.68e-2)" "unprognostic (1.03e-1)" "unprognostic (4.62e-2)" "unprognostic (1.22e-1)" SPCS2 KIAA0102 ENSG00000118363 "Signal peptidase complex subunit 2" Q15005 11 74949261-74979033 "Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epididymal principal cells: 617.1;Gastric progenitor cells: 587.0;Plasma cells: 1130.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013386, HPA017351" Approved Approved Vesicles NA NA "Cluster 32: Basophils - Transcription" "Cluster 22: Epididymis - Mixed function" "Cluster 27: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 67: Plasma cells - Plasma cell differentiation" 33 Vesicles "HPA013386: , HPA017351: " "unprognostic (5.04e-2)" "unprognostic (2.88e-2)" "unprognostic (1.65e-2)" "unprognostic (2.34e-2)" "unprognostic (1.76e-1)" "unprognostic (2.66e-2)" "unprognostic (1.49e-1)" "unprognostic (1.67e-3)" "unprognostic (4.34e-2)" "unprognostic (1.18e-1)" "potential prognostic favorable (3.00e-6)" "unprognostic (1.98e-1)" "unprognostic (5.62e-2)" "unprognostic (2.49e-2)" "unprognostic (7.98e-2)" "unprognostic (9.63e-2)" "unprognostic (2.25e-2)" "unprognostic (5.34e-2)" "unprognostic (3.06e-1)" "unprognostic (3.54e-2)" "unprognostic (1.03e-1)" "unprognostic (6.39e-3)" "unprognostic (2.98e-3)" "unprognostic (1.08e-1)" "unprognostic (8.86e-2)" "unprognostic (3.35e-1)" "unprognostic (5.97e-2)" "unprognostic (6.22e-2)" "unprognostic (7.22e-2)" "unprognostic (3.94e-1)" "unprognostic (8.81e-3)" SPCS3 "FLJ22649, PRO3567, SPC22/23, SPC3, YLR066W" ENSG00000129128 "Signal peptidase complex subunit 3" P61009 4 176319966-176332245 "Essential proteins, Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 825.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053180 Approved NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 60: Stomach - Digestion" "Cluster 27: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 44: Plasma cells - Antibody production & secretion" 42 "HPA053180: " "unprognostic (1.33e-1)" "unprognostic (1.75e-1)" "unprognostic (7.06e-2)" "unprognostic (2.62e-2)" "unprognostic (1.74e-2)" "unprognostic (5.55e-2)" "unprognostic (5.03e-2)" "unprognostic (8.74e-2)" "unprognostic (9.02e-2)" "unprognostic (1.38e-1)" "potential prognostic favorable (5.75e-4)" "unprognostic (9.15e-2)" "unprognostic (1.04e-1)" "unprognostic (1.04e-2)" "unprognostic (1.34e-1)" "unprognostic (1.19e-2)" "unprognostic (2.93e-1)" "unprognostic (1.16e-2)" "unprognostic (3.00e-1)" "unprognostic (3.28e-1)" "unprognostic (4.46e-2)" "unprognostic (6.25e-3)" "unprognostic (2.52e-2)" "unprognostic (1.02e-1)" "unprognostic (3.66e-1)" "unprognostic (6.10e-2)" "unprognostic (1.56e-3)" "unprognostic (6.58e-2)" "unprognostic (6.88e-2)" "unprognostic (1.01e-2)" "unprognostic (2.52e-2)" SPDEF "bA375E1.3, PDEF" ENSG00000124664 "SAM pointed domain containing ETS transcription factor" O95238 6 34537802-34556333 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 135.2;salivary gland: 110.2" "Cell type enhanced" "Detected in some" "Breast hormone-responsive cells: 167.6;Conjunctival goblet cells: 63.1;Gastric chief cells: 113.6;Goblet cells: 308.0;Lacrimal acinar cells: 48.9;Mucous neck cells: 86.9;Prostatic glandular cells: 225.9;Respiratory secretory cells: 54.6;Salivary acinar cells: 61.7;Submucosal glandular cells: 45.5" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Breast Invasive Carcinoma (TCGA): 161.6;Prostate Adenocarcinoma (TCGA): 555.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 12 "breast cancer: 161.2;prostate cancer: 116.2" "Breast - Breast glandular cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Region enriched" "Detected in single" 7 "midbrain: 4.2" HPA055707 Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 82: Salivary gland - Secretion" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 70: Intestinal goblet cells - Mucin production" 13 Nucleoplasm "Nucleoli, Cytosol" "HPA055707: " "unprognostic (6.25e-2)" "unprognostic (1.90e-1)" "unprognostic (1.52e-1)" "unprognostic (6.08e-2)" "unprognostic (1.29e-1)" "unprognostic (1.40e-1)" "unprognostic (1.19e-2)" "unprognostic (8.99e-3)" "unprognostic (1.14e-2)" "unprognostic (6.86e-2)" "unprognostic (2.17e-2)" "unprognostic (1.02e-1)" "unprognostic (3.90e-2)" "unprognostic (1.99e-1)" "unprognostic (1.11e-2)" "unprognostic (3.82e-1)" "unprognostic (1.76e-1)" "unprognostic (3.21e-3)" "potential prognostic unfavorable (1.73e-4)" "unprognostic (5.86e-2)" "unprognostic (1.94e-1)" "potential prognostic favorable (1.60e-4)" SPDL1 "CCDC99, FLJ20364, hSpindly" ENSG00000040275 "Spindle apparatus coiled-coil protein 1" Q96EA4 5 169583636-169604778 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 33.2" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 91.8;Early primary spermatocytes: 132.9;Erythrocyte progenitors: 52.7;Late primary spermatocytes: 108.3;Megakaryocyte progenitors: 59.3;Monocyte progenitors: 69.0;Oocytes: 87.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA044700, HPA048146" Enhanced Approved Cytosol NA Yes "Cluster 22: Eosinophils - Transcription" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 30: White matter - Myelination" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Non-specific - Cell proliferation" 13 Cytosol "HPA044700: , HPA048146: " "unprognostic (2.80e-2)" "unprognostic (2.00e-2)" "unprognostic (9.67e-2)" "unprognostic (1.18e-1)" "unprognostic (1.08e-1)" "unprognostic (4.54e-1)" "unprognostic (4.04e-2)" "unprognostic (9.72e-3)" "unprognostic (2.76e-3)" "unprognostic (4.01e-2)" "unprognostic (6.32e-2)" "potential prognostic unfavorable (4.28e-4)" "potential prognostic unfavorable (8.10e-6)" "potential prognostic unfavorable (1.31e-6)" "unprognostic (4.39e-3)" "unprognostic (8.57e-2)" "unprognostic (4.15e-2)" "unprognostic (5.72e-2)" "unprognostic (2.37e-1)" "validated prognostic unfavorable (2.81e-6)" "validated prognostic unfavorable (8.16e-7)" "unprognostic (1.41e-2)" "unprognostic (1.29e-2)" "unprognostic (9.32e-2)" "unprognostic (2.96e-2)" "unprognostic (2.42e-1)" "unprognostic (1.87e-1)" "unprognostic (8.73e-2)" "unprognostic (5.88e-2)" SPDYA "Ringo3, SPDY1, SPY1" ENSG00000163806 "Speedy/RINGO cell cycle regulator family member A" Q5MJ70 2 28782517-28850611 "Predicted intracellular proteins" "Cell cycle, DNA damage" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "testis: 30.8" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 497.4;Endometrial ciliated cells: 134.4;Endometrial luminal cells: 209.7;Late primary spermatocytes: 337.1;Neutrophils: 357.1" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Prostate Adenocarcinoma (TCGA): 7.5;Uterine Corpus Endometrial Carcinoma (TCGA): 8.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA035162, HPA066214" Enhanced Supported Nucleoplasm NA NA "Cluster 67: Testis - Mixed function" "Cluster 34: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 6 Nucleoplasm "HPA035162: , HPA066214: " "unprognostic (8.47e-2)" "unprognostic (3.96e-3)" "unprognostic (3.40e-2)" "unprognostic (1.64e-1)" "unprognostic (9.43e-3)" "unprognostic (2.53e-2)" "unprognostic (3.82e-3)" "unprognostic (3.32e-2)" "unprognostic (2.36e-1)" "unprognostic (1.94e-1)" SPDYC Ringo2 ENSG00000204710 "Speedy/RINGO cell cycle regulator family member C" Q5MJ68 11 65170233-65173374 "Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "liver: 2.9" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 5.5;Extravillous trophoblasts: 8.4;Hepatocytes: 4.1;Late spermatids: 17.9;Megakaryocytes: 6.2;Oocytes: 9.2;Platelets: 55.0;Syncytiotrophoblasts: 5.8;Undifferentiated spermatogonia: 4.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 10.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 4.8;head and neck cancer: 3.9" "Liver - Hepatocytes" "Low region specificity" "Detected in all" HPA039891 Uncertain NA NA "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 27: Breast cancer - Unknown function" "Cluster 47: Platelets - Hemostasis" 6 "HPA039891: " "unprognostic (3.50e-1)" "potential prognostic unfavorable (6.77e-5)" "unprognostic (8.04e-3)" "unprognostic (2.53e-2)" "unprognostic (1.03e-2)" "unprognostic (5.14e-2)" "unprognostic (2.21e-1)" "potential prognostic favorable (8.46e-4)" "unprognostic (3.74e-2)" "unprognostic (2.09e-1)" "unprognostic (1.85e-2)" "unprognostic (3.72e-1)" "unprognostic (3.13e-1)" "unprognostic (1.21e-1)" "unprognostic (7.57e-2)" "unprognostic (3.73e-1)" "unprognostic (5.73e-1)" SPDYE1 "Ringo1, SPDYE, WBSCR19" ENSG00000136206 "Speedy/RINGO cell cycle regulator family member E1" Q8NFV5 7 43997897-44010124 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 4 "testis: 6.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 68.5;Early spermatids: 82.4;Epicardial cells: 88.7;Late spermatids: 50.2;Myonuclei: 43.7;Retinal ganglion cells: 57.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Testis - Late spermatids" HPA051750 Supported NA NA "Cluster 32: Basophils - Transcription" "Cluster 47: Testis - Mixed function" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 56: Non-specific - Sensory perception" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "HPA051750: " "unprognostic (2.51e-1)" "unprognostic (2.30e-1)" "unprognostic (4.12e-2)" "unprognostic (2.77e-1)" "unprognostic (4.49e-2)" "unprognostic (2.01e-1)" "unprognostic (2.34e-2)" "unprognostic (2.27e-1)" "unprognostic (2.45e-3)" "unprognostic (8.20e-2)" SPDYE10 SPDYE10P ENSG00000274570 "Speedy/RINGO cell cycle regulator family member E10" P0DUX0 7 73104008-73155431 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 16.5;Early primary spermatocytes: 19.9;Epicardial cells: 34.1;Extravillous trophoblasts: 32.7;Retinal ganglion cells: 23.2;Retinal horizontal cells: 18.0;Tuft cells: 23.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" HPA051750 Uncertain NA NA "Cluster 24: Non-specific - Transcription" "Cluster 40: Non-specific - Mixed function" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "HPA051750: " SPDYE11 ENSG00000275976 "Speedy/RINGO cell cycle regulator family member E11" P0DTA3 7 73047862-73057911 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Retinal ganglion cells: 3.9;Sertoli cells: 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA051750 Uncertain NA NA "Cluster 109: Neurons - Neuronal signaling" "HPA051750: " SPDYE12 SPDYE12P ENSG00000184616 "Speedy/RINGO cell cycle regulator family member E12" P0DUX1 7 74904289-74915078 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "skeletal muscle: 1.1;testis: 1.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 24.1;Epicardial cells: 11.4;Myonuclei: 9.7;Retinal bipolar cells: 9.7;Retinal ganglion cells: 11.6;Retinal horizontal cells: 8.0;Thymocytes: 8.5" "Low cell type specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" HPA051750 Approved NA NA "Cluster 40: Non-specific - Mixed function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "HPA051750: " SPDYE13 SPDYE13P ENSG00000286038 "Speedy/RINGO cell cycle regulator family member E13" A0A494C0Z2 7 75280790-75289501 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA051750 Uncertain NA NA "HPA051750: " SPDYE14 SPDYE14P ENSG00000286137 "Speedy/RINGO cell cycle regulator family member E14" P0DUD3 7 75307376-75317429 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA051750 Uncertain NA NA "HPA051750: " SPDYE15 SPDYE15P ENSG00000286014 "Speedy/RINGO cell cycle regulator family member E15" P0DUD4 7 75335343-75345396 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA051750 Uncertain NA NA "HPA051750: " SPDYE16 ENSG00000185040 "Speedy/RINGO cell cycle regulator family member E16" A6NNV3 7 76531313-76543297 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in single" "Cell type enriched" "Detected in many" 4 "Epicardial cells: 152.4" "Cell type enhanced" "Detected in some" "midbrain-derived inhibitory: 8.7" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Adipose visceral - Mesothelial cells" HPA051750 Supported NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 47: Testis - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" "HPA051750: " "unprognostic (2.03e-2)" "unprognostic (1.16e-1)" "unprognostic (9.42e-2)" SPDYE17 ENSG00000186645 "Speedy/RINGO cell cycle regulator family member E17" P0DUD2 7 77022306-77032361 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "Early spermatids: 13.9;Epicardial cells: 13.6;Microglia: 15.7;Sertoli cells: 22.4" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA051750 Supported NA NA "Cluster 6: Non-specific - Immune response" "Cluster 56: Non-specific - Sensory perception" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "HPA051750: " "unprognostic (1.11e-1)" "unprognostic (1.54e-1)" SPDYE18 ENSG00000205482 "Speedy/RINGO cell cycle regulator family member E18" P0DV79 7 77050391-77062558 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Tissue enhanced" "Detected in some" "retina: 4.5" "Cell type enhanced" "Detected in many" "Early spermatids: 38.9;Epicardial cells: 77.3;Late spermatids: 62.1;Sertoli cells: 110.9;Suprabasal keratinocytes: 39.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" HPA051750 Approved NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 65: Non-specific - Unknown function" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" "HPA051750: " SPDYE2 MGC119295 ENSG00000205238 "Speedy/RINGO cell cycle regulator family member E2" Q495Y8 7 102551226-102563538 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Cholangiocytes: 126.4;Cytotrophoblasts: 108.2;Myonuclei: 168.1;Syncytiotrophoblasts: 140.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Late spermatids" HPA051750 Supported NA NA "Cluster 47: Testis - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 39: Non-specific - Transcription" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 1 "HPA051750: " "unprognostic (3.44e-2)" "unprognostic (6.30e-2)" "unprognostic (3.75e-1)" "unprognostic (4.29e-2)" "unprognostic (2.86e-1)" "unprognostic (4.37e-2)" "unprognostic (2.61e-2)" "unprognostic (4.41e-2)" "unprognostic (2.92e-2)" "unprognostic (4.24e-1)" "unprognostic (3.25e-1)" "unprognostic (1.38e-1)" "unprognostic (1.25e-2)" "unprognostic (1.78e-1)" "unprognostic (2.35e-2)" "unprognostic (2.57e-1)" "unprognostic (2.12e-2)" "unprognostic (4.23e-2)" "unprognostic (3.28e-1)" "unprognostic (5.20e-2)" "unprognostic (1.07e-1)" "unprognostic (2.94e-1)" "unprognostic (2.14e-1)" "unprognostic (3.17e-2)" SPDYE21 SPDYE21P ENSG00000230358 "Speedy/RINGO cell cycle regulator family member E21" A0A494C086 7 67276941-67289005 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "Myonuclei: 49.7" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA051750 Approved NA NA "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 56: Non-specific - Sensory perception" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "HPA051750: " "unprognostic (1.91e-1)" "unprognostic (2.05e-2)" SPDYE2B ENSG00000173678 "Speedy/RINGO cell cycle regulator family member E2B" A6NHP3 7 102650319-102662625 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skeletal muscle: 2.9;testis: 4.5" "Cell type enhanced" "Detected in some" "Adipocytes: 5.5;Cardiomyocytes: 16.5;Cholangiocytes: 5.3;Epicardial cells: 6.8;Myonuclei: 10.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" HPA051750 Supported NA NA "Cluster 24: Non-specific - Transcription" "Cluster 47: Testis - Mixed function" "Cluster 18: Non-specific - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 15: Non-specific - Protein processing" "HPA051750: " "unprognostic (2.61e-1)" "unprognostic (6.09e-2)" "unprognostic (2.06e-2)" "unprognostic (9.37e-2)" "unprognostic (5.34e-2)" "unprognostic (1.08e-1)" "unprognostic (2.45e-2)" "unprognostic (2.64e-1)" "unprognostic (1.03e-1)" "unprognostic (1.71e-1)" "unprognostic (2.07e-1)" SPDYE3 ENSG00000214300 "Speedy/RINGO cell cycle regulator family member E3" A6NKU9 7 100307702-100322196 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 13 "testis: 2.4" "Cell type enhanced" "Detected in many" "Leydig cells: 41.6;Retinal amacrine cells: 49.6;Retinal bipolar cells: 40.4;Retinal horizontal cells: 44.1" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" HPA051750 Supported NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "HPA051750: " "unprognostic (1.00e-1)" "unprognostic (1.18e-1)" "unprognostic (4.42e-2)" "unprognostic (1.67e-1)" SPDYE4 ENSG00000183318 "Speedy/RINGO cell cycle regulator family member E4" A6NLX3 17 8747524-8758559 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "testis: 5.2" "Group enriched" "Detected in some" 7 "Early spermatids: 33.6;Late primary spermatocytes: 61.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "HPA025704, HPA051750" Enhanced NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 56: Non-specific - Sensory perception" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 24 "HPA025704: , HPA051750: " SPDYE5 ENSG00000170092 "Speedy/RINGO cell cycle regulator family member E5" A6NIY4 7 75492320-75504316 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "testis: 1.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 39.2;Epicardial cells: 56.9;Myonuclei: 37.3;Retinal ganglion cells: 30.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" HPA051750 Approved NA NA "Cluster 47: Testis - Mixed function" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 39: Non-specific - Transcription" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "HPA051750: " "unprognostic (5.38e-2)" "unprognostic (2.76e-1)" "unprognostic (1.89e-2)" "unprognostic (3.59e-3)" "unprognostic (1.58e-1)" "unprognostic (2.99e-2)" "unprognostic (2.21e-1)" "unprognostic (1.97e-1)" "unprognostic (1.95e-1)" "unprognostic (7.01e-2)" SPDYE6 ENSG00000260097 "Speedy/RINGO cell cycle regulator family member E6" P0CI01 7 102345746-102356444 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 3.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 22.6;Cholangiocytes: 9.8;Early spermatids: 14.0;Epicardial cells: 13.6;Late spermatids: 30.3;Myonuclei: 12.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Macrophages, Testis - Late spermatids" HPA051750 Approved NA NA "Cluster 47: Testis - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 4 "HPA051750: " "unprognostic (4.40e-1)" "unprognostic (3.99e-3)" "unprognostic (1.95e-1)" "unprognostic (1.04e-1)" "unprognostic (1.43e-2)" "unprognostic (5.35e-2)" SPDYE8 SPDYE8P ENSG00000273520 "Speedy/RINGO cell cycle regulator family member E8" P0DUD1 7 73019719-73029766 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA051750 Uncertain NA NA "Cluster 108: Fibroblasts - ECM organization" "HPA051750: " SPDYE9 SPDYE9P ENSG00000262461 "Speedy/RINGO cell cycle regulator family member E9" A0A494C191 7 73075972-73086038 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Epididymal clear cells: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA051750 Uncertain NA NA "Cluster 70: Intestinal goblet cells - Mucin production" "HPA051750: " SPECC1 "CYTSB, FLJ36955, HCMOGT-1, NSP" ENSG00000128487 "Sperm antigen with calponin homology and coiled-coil domains 1" Q5M775 17 20008865-20319026 "Disease related genes, Predicted intracellular proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 42.9" "Cell type enhanced" "Detected in many" "cDC: 176.6;Choroid plexus epithelial cells: 303.6;Cone photoreceptor cells: 184.2;Erythrocyte progenitors: 365.1;Lactotrophs: 193.6;Microglia: 313.2;Monocyte progenitors: 170.9;Pericytes: 195.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 41.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Skin - Outer root sheath cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021421, HPA021430, HPA061073" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol" NA NA 7600 "Cluster 22: Eosinophils - Transcription" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 34: Non-specific - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 82: Dendritic cells - Antigen presentation" 10 "Nucleoplasm, Vesicles" "Nucleoli fibrillar center, Cytosol" "HPA021421: , HPA021430: , HPA061073: " "unprognostic (1.69e-1)" "unprognostic (5.50e-2)" "unprognostic (1.60e-2)" "unprognostic (1.22e-1)" "unprognostic (6.80e-3)" "unprognostic (2.66e-1)" "unprognostic (1.57e-2)" "unprognostic (5.67e-2)" "unprognostic (1.85e-1)" "unprognostic (7.99e-2)" "unprognostic (3.09e-2)" "unprognostic (4.62e-2)" "unprognostic (3.00e-1)" "unprognostic (1.96e-1)" "potential prognostic unfavorable (7.73e-6)" "unprognostic (2.36e-1)" "unprognostic (1.27e-2)" "unprognostic (4.56e-2)" "unprognostic (3.20e-2)" "unprognostic (2.69e-1)" "unprognostic (1.39e-2)" "unprognostic (1.69e-2)" "unprognostic (1.56e-1)" "unprognostic (7.22e-2)" "unprognostic (5.40e-2)" "unprognostic (1.65e-1)" "unprognostic (3.94e-2)" "unprognostic (1.76e-1)" "unprognostic (6.32e-2)" "unprognostic (2.25e-3)" SPECC1L "CYTSA, KIAA0376" ENSG00000100014 "Sperm antigen with calponin homology and coiled-coil domains 1 like" Q69YQ0 22 24270817-24417739 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 10 "Astrocytes: 122.4;Bergmann glia: 263.8;Brain excitatory neurons: 144.6;Brain inhibitory neurons: 119.8;Choroid plexus epithelial cells: 244.4;Ependymal cells: 115.2;Microglia: 208.5;Oligodendrocyte progenitor cells: 123.8;Oligodendrocytes: 117.5;Other brain neurons: 112.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Endothelial cells, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070614 Uncertain Supported "Actin filaments" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 21: Testis - Mixed function" "Cluster 25: Non-specific - Transcription" "Cluster 60: Prostate cancer - Unknown function" "Cluster 22: Non-specific - Basic cellular functions" 34 "Actin filaments" "HPA070614: " "unprognostic (4.11e-2)" "unprognostic (3.01e-1)" "unprognostic (1.49e-1)" "unprognostic (8.67e-2)" "unprognostic (7.37e-3)" "unprognostic (3.67e-2)" "unprognostic (5.21e-3)" "unprognostic (2.98e-1)" "unprognostic (2.86e-2)" "potential prognostic favorable (8.93e-6)" "unprognostic (3.08e-3)" "unprognostic (1.61e-1)" "unprognostic (1.94e-1)" "unprognostic (8.28e-2)" "unprognostic (2.68e-1)" "unprognostic (1.34e-2)" "unprognostic (1.63e-2)" "unprognostic (1.87e-2)" "unprognostic (7.13e-2)" "unprognostic (2.44e-2)" "unprognostic (5.23e-2)" "unprognostic (7.69e-3)" "unprognostic (7.16e-2)" "unprognostic (2.06e-3)" "unprognostic (1.51e-1)" "unprognostic (1.67e-2)" "unprognostic (1.03e-1)" "unprognostic (2.33e-1)" "unprognostic (4.18e-2)" "unprognostic (5.83e-3)" SPEF1 "C20orf28, CLAMP, DKFZP434I114, SPEF1A" ENSG00000101222 "Sperm flagellar 1" Q9Y4P9 20 3777504-3781448 "Predicted intracellular proteins" "Cilium biogenesis/degradation" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 27.6;choroid plexus: 23.5;fallopian tube: 9.3;testis: 11.9" "Group enriched" "Detected in some" 4 "Endometrial ciliated cells: 117.7;Ependymal cells: 87.0;Epididymal efferent duct ciliated cells: 213.6;Fallopian tube ciliated cells: 165.3;Respiratory ciliated cells: 166.3" "Cell type enhanced" "Detected in many" "ependymal cell: 110.2;medium spiny neuron: 79.9" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 9.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050786 Enhanced NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 17: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" 4 "HPA050786: " "unprognostic (7.46e-2)" "unprognostic (1.48e-1)" "potential prognostic favorable (6.81e-4)" "unprognostic (3.53e-2)" "potential prognostic unfavorable (2.41e-4)" "potential prognostic favorable (2.66e-4)" "unprognostic (1.53e-2)" "potential prognostic favorable (5.93e-6)" "unprognostic (8.11e-2)" "unprognostic (1.60e-1)" "unprognostic (5.42e-3)" "unprognostic (1.35e-2)" "unprognostic (2.23e-2)" "unprognostic (5.25e-2)" SPEF2 "CT122, FLJ23577, KPL2" ENSG00000152582 "Sperm flagellar 2" Q9C093 5 35617844-35814611 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 771.7;Endometrial ciliated cells: 303.3;Ependymal cells: 1033.1;Epididymal efferent duct ciliated cells: 268.6;Fallopian tube ciliated cells: 419.1;Respiratory ciliated cells: 713.1" "Group enriched" "Detected in all" 5 "choroid plexus epithelial cell: 680.5;ependymal cell: 1106.5" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "choroid plexus: 46.8" "Group enriched" "Detected in many" 6 "gdT-cell: 3.2;MAIT T-cell: 4.0;memory CD4 T-cell: 1.9;memory CD8 T-cell: 3.4;naive CD4 T-cell: 2.1;naive CD8 T-cell: 2.6;NK-cell: 3.0" "Group enriched" "Detected in many" 8 "NK-cells: 3.0;T-cells: 4.0" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039606, HPA040343" Enhanced Supported "Nuclear bodies,Primary cilium,Cytosol,Flagellar centriole,Mid piece" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 34: Ciliated cells - Cilia assembly & function" "Primary cilium, Flagellar centriole" "Nuclear bodies, Cytosol, Mid piece" "HPA039606: , HPA040343: " "unprognostic (2.07e-1)" "unprognostic (1.20e-1)" "unprognostic (1.31e-1)" "unprognostic (1.39e-1)" "unprognostic (1.36e-1)" "unprognostic (2.19e-2)" "unprognostic (1.11e-2)" "unprognostic (3.06e-2)" "unprognostic (2.87e-3)" "unprognostic (7.75e-3)" "unprognostic (1.44e-1)" "potential prognostic unfavorable (2.97e-4)" "unprognostic (1.11e-1)" "unprognostic (2.26e-1)" "unprognostic (3.56e-1)" "unprognostic (3.27e-1)" "unprognostic (1.81e-2)" "unprognostic (2.15e-1)" "unprognostic (3.38e-1)" "potential prognostic favorable (1.74e-5)" "unprognostic (5.25e-2)" "unprognostic (4.66e-2)" "unprognostic (6.42e-3)" "unprognostic (3.98e-2)" "unprognostic (2.71e-2)" "unprognostic (9.08e-2)" "unprognostic (5.34e-3)" "unprognostic (4.17e-1)" SPEG "APEG1, BPEG, KIAA1297, MGC12676, MYLK6, SPEGalpha, SPEGbeta" ENSG00000072195 "Striated muscle enriched protein kinase" Q15772 2 219434843-219493629 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Differentiation "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 206.9;intestine: 169.5" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 74.5;Astrocytes: 53.3;Bergmann glia: 45.5;Brain inhibitory neurons: 34.7;Breast myoepithelial cells: 34.4;Cardiomyocytes: 86.3;Myonuclei: 187.4;Smooth muscle cells: 122.3;Thyrotrophs: 39.2;Vascular smooth muscle cells: 103.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Breast - Breast myoepithelial cells, Heart muscle - Cardiomyocytes, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Spleen - Smooth muscle cells, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018904 Enhanced Approved Vesicles NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 62: Smooth muscle cells - Muscle contraction" 2 Vesicles "HPA018904: " "unprognostic (6.54e-2)" "unprognostic (3.57e-1)" "unprognostic (2.60e-2)" "unprognostic (5.27e-2)" "unprognostic (1.69e-2)" "unprognostic (4.64e-2)" "unprognostic (1.75e-3)" "unprognostic (2.29e-1)" "potential prognostic unfavorable (3.03e-4)" "potential prognostic unfavorable (5.74e-6)" "unprognostic (3.20e-2)" "potential prognostic unfavorable (4.44e-4)" "unprognostic (1.05e-1)" "unprognostic (2.06e-2)" "unprognostic (8.17e-2)" "unprognostic (7.22e-3)" "unprognostic (3.18e-1)" "unprognostic (5.79e-3)" "unprognostic (1.25e-2)" "unprognostic (2.02e-1)" "unprognostic (8.91e-3)" "unprognostic (3.44e-2)" "unprognostic (1.01e-1)" "unprognostic (3.41e-2)" "unprognostic (1.01e-1)" "unprognostic (4.78e-2)" "unprognostic (9.57e-2)" "unprognostic (3.08e-2)" "unprognostic (1.04e-3)" SPEGNB ENSG00000286095 "SPEG neighbor" A0A087WV53 2 219496131-219498287 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "blood vessel: 2.6;skeletal muscle: 4.0;tongue: 2.1" "Cell type enhanced" "Detected in some" "Bergmann glia: 9.9;Enterocytes: 3.4;Epididymal principal cells: 5.1;Late primary spermatocytes: 2.6;Late spermatids: 8.6;Smooth muscle cells: 8.1" "Cell type enhanced" "Detected in some" "Bergmann glia: 11.4;lower rhombic lip: 5.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Neuroblastoma: 1.9" "Adipose subcutaneous - Smooth muscle cells, Prostate - Smooth muscle cells, Skin - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 62: Smooth muscle cells - Muscle contraction" SPEM1 "C17orf83, FLJ40081" ENSG00000181323 "Spermatid maturation 1" Q8N4L4 17 7420324-7421632 "Predicted membrane proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 368 "testis: 70.6" "Cell type enriched" "Detected in some" 8 "Late spermatids: 3332.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "HPA017723, HPA077535" Approved "Golgi apparatus,Calyx" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 1 "Golgi apparatus" Calyx "HPA017723: , HPA077535: " SPEM2 C17orf74 ENSG00000184560 "SPEM family member 2" Q0P670 17 7425616-7427568 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 584 "testis: 121.6" "Cell type enriched" "Detected in some" 12 "Late spermatids: 1042.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA023649 Uncertain Approved "Golgi apparatus" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" "Golgi apparatus" "HPA023649: " SPEM3 ENSG00000283439 "SPEM family member 3" A0A1B0GUW6 17 7428857-7432820 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 592 "testis: 59.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" SPEN "KIAA0929, MINT, RBM15C, SHARP" ENSG00000065526 "Spen family transcriptional repressor" Q96T58 1 15836095-15940456 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Notch signaling pathway, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor, RNA-binding" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 8.4" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "HPA015825, HPA050257" Supported Enhanced Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 24: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 51: Secretory epithelial cells - Mixed function" 26 Nucleoplasm "HPA015825: , HPA050257: " "unprognostic (7.92e-2)" "unprognostic (3.39e-1)" "unprognostic (8.25e-2)" "unprognostic (8.55e-3)" "unprognostic (8.38e-2)" "unprognostic (4.22e-2)" "unprognostic (9.21e-2)" "unprognostic (2.31e-2)" "unprognostic (5.90e-2)" "unprognostic (3.42e-3)" "validated prognostic favorable (1.33e-5)" "validated prognostic favorable (6.06e-6)" "unprognostic (3.27e-1)" "unprognostic (4.03e-3)" "unprognostic (2.82e-1)" "unprognostic (1.47e-1)" "unprognostic (3.03e-2)" "unprognostic (1.46e-1)" "unprognostic (1.64e-1)" "unprognostic (3.98e-3)" "unprognostic (8.78e-2)" "unprognostic (5.00e-2)" "unprognostic (1.95e-2)" "unprognostic (1.53e-1)" "unprognostic (8.56e-2)" "potential prognostic favorable (7.19e-6)" "unprognostic (4.12e-1)" "unprognostic (1.80e-1)" "unprognostic (1.74e-1)" "unprognostic (7.61e-2)" "unprognostic (1.47e-1)" SPESP1 SP-ESP ENSG00000258484 "Sperm equatorial segment protein 1" Q6UW49 15 68818221-68946811 "Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "testis: 68.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 43.7;Ependymal cells: 39.1;Late primary spermatocytes: 42.1;Renal collecting duct intercalated cells: 40.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 12.9;skin cancer: 11.0" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA045936, HPA051040" Enhanced Supported "Microtubules,Cytokinetic bridge,Mitotic spindle,Acrosome,Equatorial segment" "Secreted in male reproductive system" "Developmental protein" Yes NA 37000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 57: Testis - Spermatogenesis" "Cluster 30: White matter - Myelination" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "Acrosome, Equatorial segment" "Microtubules, Cytokinetic bridge, Mitotic spindle" "HPA045936: , HPA051040: " "unprognostic (3.14e-1)" "unprognostic (9.60e-2)" "unprognostic (2.37e-1)" "unprognostic (9.49e-2)" "unprognostic (1.61e-1)" "unprognostic (1.14e-2)" "unprognostic (2.35e-2)" "unprognostic (1.10e-1)" "unprognostic (2.49e-1)" "unprognostic (2.38e-3)" "unprognostic (1.25e-2)" "unprognostic (1.84e-2)" "unprognostic (2.21e-1)" "unprognostic (1.00e-1)" "unprognostic (2.39e-1)" "unprognostic (2.01e-2)" "unprognostic (4.88e-2)" "unprognostic (3.39e-1)" "unprognostic (1.11e-1)" "unprognostic (8.21e-2)" "unprognostic (4.65e-2)" "unprognostic (8.91e-3)" "unprognostic (2.67e-2)" "unprognostic (3.13e-1)" "unprognostic (1.54e-3)" "unprognostic (1.11e-1)" "unprognostic (1.07e-1)" "potential prognostic unfavorable (2.98e-4)" SPG11 "ALS5, FLJ21439, KIAA1840" ENSG00000104133 "SPG11 vesicle trafficking associated, spatacsin" Q96JI7 15 44554818-44663688 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Amyotrophic lateral sclerosis, Charcot-Marie-Tooth disease, Hereditary spastic paraplegia, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 516.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040412, HPA040947" Approved Supported "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 11: White matter - Signal transduction" "Cluster 58: Non-specific - Nuclear processes" "Cluster 24: Neutrophils - Innate immunity signal integration" 16 "Plasma membrane, Cytosol" Nucleoli "HPA040412: , HPA040947: " "unprognostic (2.82e-2)" "unprognostic (2.10e-1)" "unprognostic (9.49e-3)" "unprognostic (1.00e-1)" "unprognostic (2.19e-1)" "unprognostic (1.81e-1)" "unprognostic (8.18e-2)" "unprognostic (3.76e-2)" "unprognostic (2.73e-1)" "unprognostic (4.02e-2)" "unprognostic (1.31e-2)" "unprognostic (1.03e-2)" "potential prognostic favorable (7.29e-4)" "unprognostic (2.57e-2)" "unprognostic (1.53e-1)" "unprognostic (4.31e-1)" "unprognostic (4.55e-2)" "unprognostic (3.64e-1)" "unprognostic (2.50e-1)" "unprognostic (3.47e-3)" "unprognostic (3.28e-3)" "unprognostic (1.14e-1)" "unprognostic (9.76e-3)" "unprognostic (1.82e-1)" "unprognostic (8.51e-2)" "unprognostic (4.16e-2)" "unprognostic (2.03e-2)" "unprognostic (1.28e-1)" "unprognostic (5.19e-2)" "unprognostic (4.13e-2)" "unprognostic (8.49e-2)" SPG21 "ABHD21, ACP33, BM-019, GL010, MAST" ENSG00000090487 "SPG21 abhydrolase domain containing, maspardin" Q9NZD8 15 64963022-64990310 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 252.6;Oocytes: 327.0;Parietal cells: 284.6;Syncytiotrophoblasts: 235.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 182.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040407, HPA040436" Approved Supported Vesicles,Cytosol NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 22: Epididymis - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 58: Non-specific - Nuclear processes" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 151 "Vesicles, Cytosol" "HPA040407: , HPA040436: " "unprognostic (7.05e-2)" "unprognostic (1.16e-2)" "unprognostic (5.98e-2)" "unprognostic (1.62e-1)" "unprognostic (3.41e-1)" "unprognostic (5.84e-2)" "unprognostic (3.19e-1)" "unprognostic (1.29e-1)" "unprognostic (5.05e-2)" "unprognostic (1.81e-2)" "potential prognostic favorable (4.50e-4)" "unprognostic (4.95e-2)" "unprognostic (7.51e-2)" "unprognostic (1.76e-2)" "unprognostic (3.44e-3)" "unprognostic (5.05e-2)" "unprognostic (7.63e-2)" "unprognostic (2.06e-2)" "unprognostic (4.37e-1)" "unprognostic (1.11e-1)" "unprognostic (2.64e-1)" "unprognostic (5.21e-3)" "unprognostic (1.00e-1)" "unprognostic (6.09e-2)" "unprognostic (1.63e-2)" "unprognostic (1.37e-1)" "unprognostic (8.58e-3)" "unprognostic (1.69e-1)" "unprognostic (4.88e-2)" "unprognostic (3.08e-1)" "unprognostic (2.79e-1)" SPG7 "CAR, CMAR, SPG5C" ENSG00000197912 "SPG7 matrix AAA peptidase subunit, paraplegin" Q9UQ90 16 89490719-89557766 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 48: Non-specific - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Transcription" 41 "unprognostic (4.25e-2)" "unprognostic (4.35e-1)" "unprognostic (1.56e-1)" "unprognostic (7.49e-3)" "unprognostic (1.26e-1)" "unprognostic (1.74e-2)" "unprognostic (1.37e-1)" "potential prognostic favorable (4.67e-5)" "unprognostic (1.02e-1)" "unprognostic (3.86e-2)" "potential prognostic favorable (6.72e-4)" "unprognostic (2.08e-1)" "potential prognostic favorable (1.01e-6)" "unprognostic (1.45e-2)" "unprognostic (2.39e-1)" "unprognostic (5.95e-3)" "unprognostic (5.04e-2)" "unprognostic (3.96e-3)" "unprognostic (1.58e-1)" "unprognostic (3.65e-1)" "unprognostic (3.79e-2)" "unprognostic (4.10e-1)" "potential prognostic unfavorable (3.27e-4)" "unprognostic (3.10e-1)" "unprognostic (4.94e-1)" "unprognostic (2.69e-1)" "unprognostic (3.85e-2)" "unprognostic (2.62e-2)" "unprognostic (1.90e-1)" "unprognostic (1.54e-1)" "unprognostic (5.53e-3)" SPHK1 SPHK ENSG00000176170 "Sphingosine kinase 1" Q9NYA1 17 76376584-76387860 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Calmodulin-binding, Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 51.7;Breast secretory cells: 104.4;Cholangiocytes: 60.9;Decidual stromal cells: 86.4;Endometrial glandular cells: 77.3;Epididymal basal cells: 61.7;Esophageal apical cells: 194.5;Lymphatic endothelial cells: 63.8;Müller glia: 141.8;Ocular epithelial cells: 54.5;Pancreatic duct cells: 77.8;Platelets: 132.4;Schwann cells: 53.6" "Cell type enhanced" "Detected in many" "lower rhombic lip: 9.2;vascular associated smooth muscle cell: 8.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 4.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "olfactory bulb: 7.6" "HPA022829, HPA028761" Uncertain Supported "Vesicles,Plasma membrane,Primary cilium,Primary cilium transition zone" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 6 "Plasma membrane" "Vesicles, Primary cilium, Primary cilium transition zone" "HPA022829: , HPA028761: " "unprognostic (8.79e-2)" "unprognostic (3.30e-2)" "unprognostic (2.90e-1)" "unprognostic (1.43e-1)" "unprognostic (7.15e-3)" "unprognostic (4.47e-2)" "potential prognostic unfavorable (9.54e-4)" "unprognostic (2.81e-1)" "unprognostic (1.79e-1)" "unprognostic (1.35e-2)" "potential prognostic unfavorable (1.77e-5)" "unprognostic (3.26e-1)" "unprognostic (5.94e-2)" "unprognostic (9.57e-3)" "unprognostic (1.51e-2)" "potential prognostic unfavorable (6.51e-5)" "unprognostic (6.52e-3)" "unprognostic (1.02e-1)" "unprognostic (1.79e-1)" "unprognostic (2.22e-2)" "unprognostic (2.28e-1)" "unprognostic (8.84e-3)" "unprognostic (3.05e-2)" "unprognostic (2.40e-2)" "unprognostic (5.75e-2)" "unprognostic (1.88e-2)" "unprognostic (3.06e-1)" "unprognostic (1.48e-1)" "unprognostic (2.03e-2)" "unprognostic (1.53e-1)" "unprognostic (2.39e-2)" SPHK2 ENSG00000063176 "Sphingosine kinase 2" Q9NRA0 19 48619291-48630717 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Retinal bipolar cells: 59.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049062 Supported Nucleoplasm NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 4 Nucleoplasm "HPA049062: " "unprognostic (8.98e-2)" "unprognostic (2.75e-1)" "unprognostic (2.29e-2)" "unprognostic (1.07e-1)" "unprognostic (9.84e-2)" "unprognostic (4.69e-2)" "unprognostic (1.52e-1)" "unprognostic (2.48e-1)" "unprognostic (4.41e-3)" "unprognostic (2.79e-1)" "unprognostic (7.36e-2)" "unprognostic (1.18e-1)" "unprognostic (2.26e-3)" "unprognostic (1.21e-1)" "unprognostic (2.11e-2)" "unprognostic (1.15e-2)" "unprognostic (2.10e-1)" "unprognostic (1.19e-1)" "unprognostic (5.91e-3)" "unprognostic (3.62e-1)" "unprognostic (1.10e-1)" "unprognostic (1.03e-3)" "unprognostic (8.53e-2)" "unprognostic (1.69e-1)" "unprognostic (1.98e-1)" "unprognostic (1.75e-2)" "unprognostic (5.50e-2)" "unprognostic (7.49e-2)" "unprognostic (1.18e-1)" "unprognostic (4.62e-2)" "unprognostic (1.06e-1)" SPHKAP SKIP ENSG00000153820 "SPHK1 interactor, AKAP domain containing" Q2M3C7 2 227979955-228181687 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 12 "brain: 33.6;heart muscle: 27.3" "Group enriched" "Detected in some" 8 "Brain excitatory neurons: 425.1;Brain inhibitory neurons: 278.9;Cardiomyocytes: 465.7;Granulosa cells: 130.6;Other brain neurons: 278.3;Retinal amacrine cells: 218.8" "Cell type enhanced" "Detected in all" "hippocampal dentate gyrus: 929.0;midbrain-derived inhibitory: 1973.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Bone cancer: 1.4" "Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042499, HPA048168" Enhanced NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 35: Non-specific - DNA binding" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 35: Neurons - Synaptic function & neurogenesis" 1 "HPA042499: , HPA048168: " "potential prognostic favorable (5.76e-5)" SPI1 "OF, PU.1, SFPI1, SPI-1, SPI-A" ENSG00000066336 "Spi-1 proto-oncogene" P17947 11 47354860-47378547 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, RNA-binding" "Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 316.4;lung: 98.6;lymphoid tissue: 167.9" "Cell type enhanced" "Detected in many" "cDC: 416.6;Hofbauer cells: 502.2;Kupffer cells: 449.9;Macrophages: 295.4;Monocyte progenitors: 229.0;monocytes: 448.8;Neutrophil progenitors: 394.2;Neutrophils: 1363.9" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 118.3;leukocyte: 53.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 180.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 180.0" "Group enriched" "Detected in some" 15 "Leukemia: 134.6;lymphoma: 69.7" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Lung - Neutrophils_2, Minor Salivary Gland - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Spleen - Neutrophils_2, Stomach - Macrophages, Testis - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004079, HPA044653" Enhanced Supported Nucleoplasm NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 25 Nucleoplasm "CAB004079: , HPA044653: " "unprognostic (3.27e-2)" "unprognostic (8.89e-3)" "unprognostic (3.79e-2)" "unprognostic (3.28e-2)" "unprognostic (4.35e-2)" "unprognostic (3.73e-1)" "unprognostic (1.08e-2)" "unprognostic (1.22e-1)" "unprognostic (2.90e-2)" "unprognostic (3.30e-1)" "unprognostic (2.50e-2)" "unprognostic (2.74e-1)" "unprognostic (6.94e-2)" "unprognostic (2.90e-2)" "unprognostic (1.54e-1)" "unprognostic (1.79e-2)" "unprognostic (1.69e-1)" "unprognostic (1.39e-1)" "unprognostic (2.57e-1)" "unprognostic (2.15e-1)" "unprognostic (6.71e-2)" "unprognostic (1.22e-1)" "unprognostic (3.11e-3)" "unprognostic (2.49e-1)" "unprognostic (8.10e-2)" "unprognostic (1.18e-1)" "unprognostic (2.91e-2)" "unprognostic (8.75e-2)" "unprognostic (7.46e-3)" "unprognostic (2.17e-1)" "unprognostic (1.69e-1)" SPIB SPI-B ENSG00000269404 "Spi-B transcription factor" Q01892 19 50418938-50431314 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "intestine: 25.2;lymphoid tissue: 93.0" "Group enriched" "Detected in some" 5 "B-cells: 65.7;Colonocytes: 90.1;pDCs: 250.0;Tuft cells: 230.6" "Cell type enriched" "Detected in single" 5 "leukocyte: 4.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 54 "memory B-cell: 309.0;naive B-cell: 261.6;plasmacytoid DC: 574.0" "Group enriched" "Detected in many" 112 "B-cells: 309.0;dendritic cells: 574.0" "Cancer enriched" "Detected in some" 15 "lymphoma: 292.0" "Colon - Colon enterocytes, Liver - T-cells, Spleen - B-cells (Spleen)" "Not detected" "Not detected" "Not detected" "Not detected" HPA018523 Uncertain NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 3 "HPA018523: " "unprognostic (2.57e-1)" "potential prognostic favorable (6.72e-4)" "unprognostic (4.27e-3)" "unprognostic (2.24e-1)" "unprognostic (2.67e-1)" "unprognostic (1.12e-3)" "potential prognostic favorable (4.52e-5)" "potential prognostic unfavorable (3.45e-6)" "unprognostic (7.04e-2)" "unprognostic (5.92e-2)" "unprognostic (3.47e-1)" "potential prognostic favorable (2.45e-4)" "unprognostic (1.79e-1)" "unprognostic (6.42e-2)" "unprognostic (1.72e-1)" "unprognostic (1.27e-1)" "unprognostic (7.84e-2)" "unprognostic (8.42e-2)" "unprognostic (1.91e-1)" "unprognostic (9.99e-3)" "unprognostic (8.59e-2)" "unprognostic (3.21e-1)" "unprognostic (2.13e-1)" "unprognostic (4.54e-2)" "unprognostic (4.60e-2)" "unprognostic (3.87e-3)" SPIC "MGC40611, SPI-C" ENSG00000166211 "Spi-C transcription factor" Q8N5J4 12 101475336-101486997 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "lymphoid tissue: 29.0" "Cell type enriched" "Detected in some" 4 "Kupffer cells: 61.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Testicular Germ Cell Tumor (TCGA): 1.9" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "intermediate monocyte: 1.1" "Lineage enriched" "Detected in single" 8 "monocytes: 1.1" "Cancer enriched" "Detected in single" 9 "lymphoma: 1.9" "Liver - Kupffer cells, Spleen - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 2 "unprognostic (3.35e-1)" "unprognostic (2.00e-1)" SPICE1 "CCDC52, SPICE" ENSG00000163611 "Spindle and centriole associated protein 1" Q8N0Z3 3 113442718-113515187 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 33.4;Bergmann glia: 43.5;Brain excitatory neurons: 28.8;Choroid plexus epithelial cells: 71.9;Distal convoluted tubule cells: 47.3;Ependymal cells: 83.5;Loop of henle epithelial cells: 41.9;Oligodendrocyte progenitor cells: 28.5;Papillary tip epithelial cells: 41.0;Podocytes: 42.6;Proximal tubule cells: 45.5;Renal collecting duct intercalated cells: 40.3;Renal collecting duct principal cells: 44.5;Renal connecting tubule cells: 51.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064843 Approved Supported "Centrosome,Basal body" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 34: Ciliated cells - Cilia assembly & function" 26 "Centrosome, Basal body" "HPA064843: " "unprognostic (7.54e-3)" "unprognostic (1.49e-1)" "unprognostic (5.94e-2)" "unprognostic (2.42e-1)" "unprognostic (1.11e-1)" "unprognostic (1.90e-1)" "unprognostic (1.16e-1)" "unprognostic (1.94e-1)" "unprognostic (5.34e-3)" "potential prognostic favorable (1.52e-4)" "unprognostic (3.91e-2)" "unprognostic (3.88e-1)" "unprognostic (4.63e-2)" "unprognostic (1.64e-1)" "unprognostic (3.88e-2)" "unprognostic (3.16e-3)" "unprognostic (7.14e-2)" "unprognostic (2.61e-1)" "unprognostic (1.36e-1)" "unprognostic (5.42e-2)" "potential prognostic unfavorable (3.38e-4)" "unprognostic (1.79e-2)" "unprognostic (4.22e-2)" "unprognostic (3.73e-2)" "unprognostic (3.59e-2)" "unprognostic (8.65e-3)" "unprognostic (2.26e-2)" "unprognostic (2.69e-1)" "unprognostic (1.05e-2)" "unprognostic (3.13e-1)" SPIDR KIAA0146 ENSG00000164808 "Scaffold protein involved in DNA repair" Q14159 8 47260878-47736306 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027201, HPA041582" Approved Supported Nucleoplasm NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 48: Non-specific - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 14 Nucleoplasm "HPA027201: , HPA041582: " "unprognostic (8.90e-3)" "unprognostic (1.64e-1)" "unprognostic (7.47e-2)" "unprognostic (9.52e-2)" "unprognostic (6.93e-2)" "unprognostic (1.78e-3)" "unprognostic (4.50e-2)" "unprognostic (2.68e-2)" "potential prognostic unfavorable (4.56e-7)" "unprognostic (1.07e-1)" "unprognostic (1.09e-1)" "unprognostic (3.10e-1)" "unprognostic (1.29e-2)" "unprognostic (1.78e-1)" "unprognostic (1.01e-1)" "unprognostic (3.39e-2)" "unprognostic (2.44e-1)" "potential prognostic unfavorable (2.53e-4)" "unprognostic (4.89e-2)" "unprognostic (2.13e-1)" "unprognostic (2.15e-3)" "unprognostic (1.99e-1)" "unprognostic (9.95e-2)" "potential prognostic favorable (2.51e-4)" "unprognostic (4.98e-3)" "unprognostic (2.52e-1)" "unprognostic (3.69e-1)" "unprognostic (1.83e-1)" "unprognostic (9.66e-2)" SPIN1 "SPIN, TDRD24" ENSG00000106723 "Spindlin 1" Q9Y657 9 88388430-88478694 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Meiosis, Wnt signaling pathway" "Chromatin regulator, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Spleen - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000162, HPA068784" Uncertain Supported Nucleoplasm NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 65: Brain - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 51: Secretory epithelial cells - Mixed function" 24 Nucleoplasm "HPA000162: , HPA068784: " "unprognostic (4.44e-2)" "unprognostic (4.79e-1)" "unprognostic (3.94e-2)" "unprognostic (9.69e-2)" "unprognostic (7.91e-2)" "unprognostic (1.68e-3)" "unprognostic (1.31e-1)" "unprognostic (1.84e-1)" "unprognostic (3.91e-1)" "unprognostic (2.68e-1)" "validated prognostic favorable (5.85e-8)" "validated prognostic favorable (2.78e-5)" "unprognostic (3.89e-2)" "unprognostic (1.30e-2)" "unprognostic (8.20e-2)" "unprognostic (3.53e-2)" "unprognostic (2.57e-1)" "unprognostic (6.54e-3)" "unprognostic (3.74e-1)" "unprognostic (1.40e-1)" "unprognostic (1.65e-1)" "unprognostic (1.42e-1)" "unprognostic (6.91e-2)" "unprognostic (1.06e-1)" "unprognostic (6.49e-2)" "unprognostic (6.59e-2)" "unprognostic (5.57e-2)" "unprognostic (3.03e-2)" "unprognostic (5.31e-1)" "unprognostic (3.33e-2)" "unprognostic (2.48e-1)" SPIN2A "DXF34, SPIN2, TDRD25" ENSG00000147059 "Spindlin family member 2A" Q99865 X 57134530-57137523 "Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 6.3;Cardiomyocytes: 3.0;Epicardial cells: 2.3;Fibro-adipogenic progenitors: 2.8;Medullary thymic epithelial cells: 2.4;Megakaryocytes: 12.4;Myonuclei: 4.2;Myosatellite cells: 2.4;Retinal bipolar cells: 2.5" "Low cell type specificity" "Detected in some" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "HPA000162, HPA069835" Uncertain Approved Nucleoplasm NA NA "Cluster 64: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 56: Non-specific - Sensory perception" "Cluster 89: Adipocytes - Lipid metabolism" 1 Nucleoplasm "HPA000162: , HPA069835: " "unprognostic (5.16e-2)" "unprognostic (1.20e-2)" "unprognostic (3.07e-1)" "unprognostic (1.06e-3)" "unprognostic (2.04e-2)" SPIN2B "SPIN-2, TDRD26" ENSG00000186787 "Spindlin family member 2B" Q9BPZ2 X 57118551-57121548 "Predicted intracellular proteins" "Apoptosis, Cell cycle" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Platelets: 29.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA000162, HPA069835" Uncertain Approved Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 64: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 36: Non-specific - mRNA processing" "Cluster 98: Neurons - Neurotransmission & signaling" 5 Nucleoplasm "HPA000162: , HPA069835: " "unprognostic (1.01e-1)" "potential prognostic unfavorable (4.62e-4)" "unprognostic (3.46e-2)" "unprognostic (1.34e-2)" "unprognostic (9.06e-2)" "unprognostic (3.83e-2)" "unprognostic (1.02e-1)" "unprognostic (1.03e-3)" "unprognostic (9.24e-2)" "unprognostic (4.02e-2)" "potential prognostic favorable (7.35e-5)" "unprognostic (1.11e-1)" "unprognostic (7.39e-2)" "unprognostic (2.13e-3)" "unprognostic (6.62e-2)" "unprognostic (3.70e-2)" "unprognostic (1.21e-2)" "unprognostic (1.67e-2)" "unprognostic (9.27e-3)" "unprognostic (4.52e-2)" "unprognostic (1.28e-1)" "unprognostic (2.63e-3)" "unprognostic (3.02e-1)" "unprognostic (3.46e-2)" "unprognostic (1.90e-3)" "unprognostic (7.97e-2)" "unprognostic (2.09e-2)" "unprognostic (6.12e-2)" "unprognostic (1.27e-1)" "unprognostic (1.32e-1)" "unprognostic (1.18e-1)" SPIN3 TDRD27 ENSG00000204271 "Spindlin family member 3" Q5JUX0 X 56818298-56995827 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 53.3;Brain excitatory neurons: 59.4;Brain inhibitory neurons: 50.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000727 Uncertain Approved Nucleoplasm NA NA "Cluster 32: Basophils - Transcription" "Cluster 65: Brain - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 4 Nucleoplasm "HPA000727: " "potential prognostic favorable (4.63e-4)" "unprognostic (9.18e-3)" "unprognostic (2.95e-2)" "unprognostic (1.80e-1)" "unprognostic (1.44e-2)" "unprognostic (3.30e-2)" "unprognostic (4.33e-2)" "unprognostic (1.86e-3)" "unprognostic (3.57e-2)" "unprognostic (1.26e-3)" "unprognostic (2.46e-1)" "unprognostic (1.64e-2)" "unprognostic (2.08e-3)" "unprognostic (1.92e-2)" "unprognostic (1.97e-1)" "unprognostic (1.99e-2)" "unprognostic (3.20e-1)" "unprognostic (4.09e-2)" "unprognostic (4.61e-2)" "unprognostic (9.55e-2)" "unprognostic (1.49e-1)" "unprognostic (7.55e-2)" "unprognostic (1.03e-1)" "unprognostic (2.25e-2)" "unprognostic (7.85e-2)" "unprognostic (1.51e-1)" "unprognostic (2.26e-1)" "unprognostic (2.98e-2)" "unprognostic (1.44e-2)" "unprognostic (9.18e-3)" "unprognostic (2.32e-1)" SPIN4 "FLJ44984, TDRD28" ENSG00000186767 "Spindlin family member 4" Q56A73 X 63347228-63351332 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 2.2;Loop of henle epithelial cells: 2.3;Podocytes: 5.9;Proximal tubule cells: 3.0;Renal collecting duct intercalated cells: 1.5;Renal collecting duct principal cells: 1.4;Renal connecting tubule cells: 2.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 2.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA001014, HPA044559" Uncertain Approved Nucleoplasm,Centrosome,Cytosol NA Yes "Cluster 42: Non-specific - Vesicular transport" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 47: Leukemia - Hemostasis" "Cluster 105: Non-specific - Mixed function" 6 "Nucleoplasm, Cytosol" Centrosome "HPA001014: , HPA044559: " "unprognostic (3.37e-2)" "unprognostic (3.00e-1)" "unprognostic (7.19e-3)" "unprognostic (1.92e-1)" "unprognostic (1.31e-1)" "unprognostic (2.88e-2)" "unprognostic (3.21e-1)" "unprognostic (2.10e-1)" "unprognostic (2.62e-1)" "potential prognostic favorable (7.31e-4)" "unprognostic (3.68e-1)" "unprognostic (9.03e-3)" "unprognostic (1.39e-2)" "potential prognostic unfavorable (6.08e-4)" "unprognostic (4.50e-2)" "unprognostic (1.06e-1)" "unprognostic (2.77e-2)" "unprognostic (6.04e-2)" "unprognostic (1.63e-1)" "potential prognostic unfavorable (8.22e-4)" "unprognostic (4.17e-3)" "unprognostic (1.20e-1)" "unprognostic (7.00e-3)" "unprognostic (1.38e-1)" "unprognostic (3.34e-2)" "unprognostic (1.16e-2)" "unprognostic (2.36e-1)" "unprognostic (6.64e-2)" "unprognostic (1.06e-1)" SPINDOC "C11orf84, SPIN-DOC" ENSG00000168005 "Spindlin interactor and repressor of chromatin binding" Q9BUA3 11 63813456-63827716 "Predicted intracellular proteins" "DNA damage, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Tuft cells: 34.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040128, HPA050313" Uncertain Approved "Nuclear speckles" NA NA "Cluster 67: Testis - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 20: Non-specific - Transcription regulation" 7 "Nuclear speckles" "HPA040128: , HPA050313: " "unprognostic (1.29e-2)" "potential prognostic unfavorable (1.70e-4)" "unprognostic (3.95e-2)" "unprognostic (6.87e-3)" "unprognostic (2.99e-3)" "unprognostic (2.04e-1)" "unprognostic (5.49e-2)" "unprognostic (1.72e-2)" "unprognostic (1.82e-1)" "unprognostic (3.14e-2)" "unprognostic (8.53e-2)" "potential prognostic unfavorable (1.88e-5)" "potential prognostic unfavorable (2.26e-6)" "unprognostic (8.11e-3)" "unprognostic (3.87e-3)" "unprognostic (1.57e-1)" "unprognostic (6.16e-2)" "unprognostic (4.92e-2)" "unprognostic (2.85e-1)" "unprognostic (6.13e-2)" "unprognostic (2.48e-2)" "unprognostic (1.49e-3)" "unprognostic (2.85e-1)" "unprognostic (2.41e-1)" "unprognostic (3.42e-1)" "unprognostic (9.03e-2)" "unprognostic (4.54e-1)" "unprognostic (1.21e-1)" "unprognostic (1.56e-1)" SPINK1 "PCTT, PSTI, Spink3, TATI" ENSG00000164266 "Serine peptidase inhibitor Kazal type 1" P00995 5 147824572-147831671 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 31 "pancreas: 49964.7" "Cell type enriched" "Detected in many" 7 "Pancreatic acinar cells: 38910.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Pancreatic Adenocarcinoma (TCGA): 3790.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 210.0;liver cancer: 259.1" "Colon - Colon enterocytes" "Not detected" "Not detected" "Not detected" "Not detected" "CAB026366, HPA027498" Enhanced "Secreted to digestive system" "Enzyme inhibitor" NA NA 23000000 "Cluster 8: Pancreas - Proteolysis" "Cluster 11: White matter - Signal transduction" "Cluster 66: Non-specific - Mitochondria" "Cluster 5: Pancreatic acinar cells - Pancreatic exocrine secretion" "CAB026366: , HPA027498: " "unprognostic (1.86e-2)" "unprognostic (3.44e-1)" "unprognostic (5.77e-1)" "unprognostic (1.04e-1)" "unprognostic (1.92e-2)" "unprognostic (5.01e-2)" "unprognostic (2.10e-3)" "unprognostic (2.23e-1)" "potential prognostic unfavorable (3.69e-4)" "unprognostic (3.32e-1)" "potential prognostic unfavorable (2.93e-4)" "unprognostic (1.10e-2)" "potential prognostic unfavorable (4.83e-4)" "unprognostic (7.22e-3)" "unprognostic (1.40e-1)" "unprognostic (6.01e-2)" "unprognostic (1.28e-1)" "unprognostic (4.42e-2)" "unprognostic (1.63e-1)" "unprognostic (1.88e-1)" "unprognostic (1.29e-1)" "unprognostic (6.79e-2)" "unprognostic (9.73e-3)" "unprognostic (1.47e-1)" "unprognostic (8.46e-2)" "unprognostic (3.19e-2)" "unprognostic (8.94e-3)" "unprognostic (2.28e-2)" "unprognostic (1.84e-1)" "unprognostic (3.49e-1)" SPINK13 "HESPINTOR, LiESP6, MGC149260, SPINK5L3" ENSG00000214510 "Serine peptidase inhibitor Kazal type 13" Q1W4C9 5 148268180-148286255 "Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "epididymis: 310.2" "Group enriched" "Detected in some" 5 "Epididymal efferent duct absorptive cells: 224.4;Epididymal principal cells: 844.9" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 17.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 8 "cervical cancer: 97.7" "Kidney - Macrophages, Pituitary gland - Gonadotropes, Skin - Hair cortex cells, Skin - Outer root sheath cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA036456 Approved Approved "Nucleoplasm,Plasma membrane" "Secreted in male reproductive system" "Enzyme inhibitor" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" 1 "Plasma membrane" Nucleoplasm "HPA036456: " "unprognostic (1.70e-1)" "unprognostic (8.04e-2)" "potential prognostic unfavorable (6.29e-4)" "unprognostic (2.74e-3)" "unprognostic (1.36e-3)" "unprognostic (5.35e-3)" "unprognostic (7.62e-2)" "unprognostic (2.69e-1)" "unprognostic (2.55e-1)" "unprognostic (1.67e-2)" "potential prognostic favorable (2.89e-4)" "unprognostic (8.23e-2)" SPINK14 SPINK5L2 ENSG00000196800 "Serine peptidase inhibitor Kazal type 14 (putative)" Q6IE38 5 148168546-148175619 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 4.3;Epididymal principal cells: 1.8;Gastric progenitor cells: 1.3;Parietal cells: 1.8;Respiratory deuterosomal cells: 1.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Lung Adenocarcinoma (TCGA): 1.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Minor Salivary Gland - Minor salivary glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted - unknown location" "Enzyme inhibitor" NA NA "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" "unprognostic (1.79e-1)" "unprognostic (8.20e-3)" "unprognostic (5.31e-2)" SPINK2 HUSI-II ENSG00000128040 "Serine peptidase inhibitor Kazal type 2" P20155 4 56809860-56821742 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 15 "epididymis: 4955.9" "Cell type enriched" "Detected in many" 6 "Epididymal principal cells: 27209.1" "Cell type enhanced" "Detected in some" "endothelial cell: 5.0;leukocyte: 4.1" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 6.4" "Region enriched" "Detected in single" 5 "choroid plexus: 3.7" "Immune cell enriched" "Detected in many" 7 "NK-cell: 143.9" "Lineage enriched" "Detected in many" 7 "NK-cells: 143.9" "Group enriched" "Detected in some" 12 "Leukemia: 23.4;lymphoma: 17.3;Myeloma: 13.7" "Pituitary gland - Gonadotropes, Stomach - Plasma cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB020824, HPA026813" Enhanced Supported "Acrosome,Equatorial segment" "Secreted to blood" "Enzyme inhibitor" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 22: Epididymis - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" 6 Acrosome "Equatorial segment" "CAB020824: , HPA026813: " "unprognostic (2.47e-1)" "unprognostic (3.17e-2)" "potential prognostic favorable (2.66e-4)" "unprognostic (1.85e-1)" "unprognostic (9.57e-3)" "unprognostic (4.99e-3)" "unprognostic (2.22e-1)" "unprognostic (2.85e-2)" "unprognostic (2.29e-1)" SPINK4 "MGC133107, PEC-60" ENSG00000122711 "Serine peptidase inhibitor Kazal type 4" O60575 9 33218365-33248567 "Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "intestine: 914.5" "Cell type enriched" "Detected in many" 80 "Goblet cells: 9485.8" "Not detected" "Not detected" "Group enriched" "Detected in many" 9 "Colon Adenocarcinoma (TCGA): 836.1;Pancreatic Adenocarcinoma (TCGA): 934.5;Rectum Adenocarcinoma (TCGA): 592.9;Stomach Adenocarcinoma (TCGA): 352.9" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 6 "basophil: 1.8" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.8" "Cancer enriched" "Detected in many" 5 "colorectal cancer: 146.3" "Colon - Colon enterocytes" "Region enhanced" "Detected in single" "pons and medulla: 1.1" "Low region specificity" "Detected in some" HPA007286 Enhanced Approved "Nucleoplasm,Golgi apparatus,Vesicles" "Secreted to digestive system" "Enzyme inhibitor" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 77: Intestine - Digestion" "Cluster 2: Neurons - Nucleosome" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 70: Intestinal goblet cells - Mucin production" 1 "Golgi apparatus, Vesicles" Nucleoplasm "HPA007286: " "unprognostic (3.52e-1)" "unprognostic (2.20e-2)" "unprognostic (8.89e-2)" "unprognostic (1.92e-2)" "unprognostic (1.17e-3)" "unprognostic (5.45e-3)" "unprognostic (1.06e-2)" "unprognostic (1.04e-3)" "unprognostic (1.92e-1)" "unprognostic (4.03e-2)" "unprognostic (1.76e-1)" "unprognostic (2.06e-1)" "unprognostic (1.63e-2)" "potential prognostic unfavorable (3.97e-4)" "unprognostic (1.04e-1)" "unprognostic (2.52e-1)" SPINK5 "DKFZp686K19184, FLJ21544, FLJ97536, FLJ97596, FLJ99794, LEKTI, LETKI, NETS, NS, VAKTI" ENSG00000133710 "Serine peptidase inhibitor Kazal type 5" Q9NQ38 5 148025683-148137382 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Hypotrichosis, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "cervix: 538.7;esophagus: 953.6;lymphoid tissue: 274.6;skin 1: 300.2;vagina: 552.2" "Cell type enriched" "Detected in many" 7 "Esophageal apical cells: 47706.3" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 46.2;Head and Neck Squamous Cell Carcinoma (TCGA): 71.7" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 21.4" "Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary gland basal cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA009067, HPA011351, CAB015347" Enhanced Enhanced Vesicles "Secreted in other tissues" "Enzyme inhibitor" NA NA 43000000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" Vesicles "CAB015347: , HPA009067: , HPA011351: " "unprognostic (1.18e-1)" "unprognostic (2.09e-2)" "unprognostic (1.06e-1)" "unprognostic (1.11e-1)" "unprognostic (2.27e-1)" "unprognostic (1.45e-3)" "unprognostic (1.26e-1)" "potential prognostic favorable (3.90e-5)" "unprognostic (1.78e-1)" "unprognostic (6.02e-2)" "unprognostic (3.98e-1)" "unprognostic (1.11e-2)" "unprognostic (1.96e-2)" "potential prognostic favorable (7.12e-4)" "unprognostic (2.61e-1)" "unprognostic (2.27e-1)" "unprognostic (2.32e-3)" "unprognostic (9.23e-2)" "unprognostic (4.34e-1)" "unprognostic (3.06e-1)" "unprognostic (3.75e-2)" "unprognostic (1.27e-1)" "unprognostic (1.56e-1)" "unprognostic (3.03e-1)" "unprognostic (1.67e-1)" "unprognostic (1.75e-2)" SPINK6 "BUSI2, MGC21394, UNQ844" ENSG00000178172 "Serine peptidase inhibitor Kazal type 6" Q6UWN8 5 148202794-148215137 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 12.5;cervix: 13.1;salivary gland: 8.9;vagina: 10.9" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 8.7;Esophageal apical cells: 28.1" "Cell type enhanced" "Detected in single" "Bergmann glia: 1.6" "Group enriched" "Detected in many" 7 "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 34.4;Head and Neck Squamous Cell Carcinoma (TCGA): 73.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 21 "cervical cancer: 1232.0" "Adipose visceral - Adipocytes (Visceral)" "Not detected" "Not detected" "Not detected" "Not detected" HPA011039 Uncertain "Secreted - unknown location" "Enzyme inhibitor" NA NA "Cluster 64: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" "HPA011039: " "unprognostic (1.80e-1)" "unprognostic (4.01e-2)" "potential prognostic favorable (3.02e-4)" "unprognostic (5.47e-2)" "unprognostic (5.66e-2)" "unprognostic (2.40e-1)" "unprognostic (2.73e-1)" "unprognostic (1.00e-1)" "unprognostic (3.43e-1)" "unprognostic (7.55e-1)" SPINK7 "ECG2, ECRG2" ENSG00000145879 "Serine peptidase inhibitor Kazal type 7" P58062 5 148312419-148315922 "Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "cervix: 517.3;esophagus: 627.5;vagina: 601.8" "Cell type enriched" "Detected in some" 147 "Esophageal apical cells: 24074.9" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 20.1;Head and Neck Squamous Cell Carcinoma (TCGA): 75.9;Kidney Chromophobe (TCGA): 23.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "cervical cancer: 4.4;Esophageal cancer: 3.7;head and neck cancer: 10.1;lung cancer: 4.7" "Skin - Hair cortex cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA036294 Enhanced "Secreted in other tissues" "Enzyme inhibitor" NA NA 94000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 84: Apical squamous epithelium - Cornification" 18 "HPA036294: " "unprognostic (2.00e-1)" "unprognostic (1.74e-1)" "unprognostic (1.82e-2)" "unprognostic (5.78e-3)" "unprognostic (2.10e-2)" "unprognostic (2.29e-1)" "unprognostic (1.38e-1)" "unprognostic (2.41e-2)" "unprognostic (9.67e-2)" SPINK8 ENSG00000229453 "Serine peptidase inhibitor Kazal type 8 (putative)" P0C7L1 3 48306842-48333661 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "bone marrow: 7.9;breast: 14.9;fallopian tube: 6.7;placenta: 5.2" "Cell type enhanced" "Detected in some" "Breast hormone-responsive cells: 22.0;Breast lactating cells: 46.7;Breast secretory cells: 8.6;Esophageal apical cells: 70.3;Neutrophil progenitors: 13.1;Neutrophils: 11.4;Tuft cells: 11.5" "Cell type enhanced" "Detected in many" "endothelial cell: 29.3;hippocampal dentate gyrus: 29.2" "Cancer enhanced" "Detected in some" "Breast Invasive Carcinoma (TCGA): 15.7;Glioblastoma Multiforme (TCGA): 17.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "eosinophil: 1.1;neutrophil: 1.8" "Lineage enriched" "Detected in single" 7 "granulocytes: 1.8" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Prostate - Prostate glandular cells" "Region enriched" "Detected in many" 9 "hippocampal formation: 73.7" "Low region specificity" "Detected in all" HPA053151 Uncertain "Secreted to blood" "Enzyme inhibitor" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 40: Non-specific - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 27: Breast cancer - Unknown function" "Cluster 84: Apical squamous epithelium - Cornification" "HPA053151: " "potential prognostic unfavorable (6.76e-4)" "unprognostic (3.28e-1)" "unprognostic (3.90e-2)" "unprognostic (3.21e-2)" "unprognostic (3.93e-1)" "unprognostic (7.30e-2)" "unprognostic (2.78e-1)" SPINK9 ENSG00000204909 "Serine peptidase inhibitor Kazal type 9" Q5DT21 5 148321203-148339852 "Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 2.3;lymphoid tissue: 2.6;retina: 2.0" "Cell type enriched" "Detected in some" 4 "Cardiomyocytes: 90.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 6.4" "Lineage enriched" "Detected in many" 4 "granulocytes: 6.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" HPA038288 Uncertain Approved Nucleoplasm,Vesicles "Secreted in other tissues" "Enzyme inhibitor" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 9: Non-specific - Receptor signaling" "Cluster 56: Non-specific - Sensory perception" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 1 "Nucleoplasm, Vesicles" "HPA038288: " "unprognostic (1.01e-1)" "unprognostic (4.47e-2)" "unprognostic (5.64e-2)" "unprognostic (2.03e-3)" "unprognostic (1.48e-1)" "unprognostic (2.77e-2)" "unprognostic (9.30e-2)" "potential prognostic unfavorable (1.20e-4)" "unprognostic (1.82e-2)" "unprognostic (1.67e-1)" "unprognostic (2.65e-1)" "unprognostic (3.07e-3)" "unprognostic (2.13e-1)" "unprognostic (1.26e-1)" "unprognostic (1.51e-1)" "unprognostic (1.91e-1)" "unprognostic (3.08e-1)" "unprognostic (6.36e-2)" "unprognostic (5.49e-3)" "unprognostic (5.77e-2)" "unprognostic (2.14e-3)" "unprognostic (3.67e-2)" "unprognostic (1.53e-1)" "unprognostic (2.19e-1)" "unprognostic (1.13e-1)" "unprognostic (2.21e-2)" "unprognostic (1.17e-1)" SPINT1 "HAI, HAI-1, MANSC2" ENSG00000166145 "Serine peptidase inhibitor, Kunitz type 1" O43278 15 40844018-40858207 "Cancer-related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 223.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1470.5;Enterocytes: 488.4;Esophageal apical cells: 2822.0;Migrating cytotrophoblasts: 977.6;Syncytiotrophoblasts: 2062.9" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 6.8;leukocyte: 5.3;upper rhombic lip: 6.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Liver - Cholangiocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Stomach - Gastric mucous cells, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA006903, HPA031178" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" "Enzyme inhibitor" NA NA 10000000 "Cluster 7: Non-specific - Innate immune response" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 84: Apical squamous epithelium - Cornification" 17 "Plasma membrane, Cytosol" Nucleoplasm "HPA006903: , HPA031178: " "unprognostic (6.42e-2)" "unprognostic (2.17e-3)" "unprognostic (1.32e-1)" "potential prognostic unfavorable (6.56e-4)" "unprognostic (4.43e-1)" "unprognostic (5.38e-2)" "unprognostic (4.18e-2)" "unprognostic (3.45e-3)" "unprognostic (1.06e-1)" "unprognostic (1.21e-1)" "potential prognostic favorable (3.32e-7)" "unprognostic (7.89e-2)" "unprognostic (2.84e-2)" "unprognostic (2.36e-2)" "unprognostic (2.03e-1)" "unprognostic (2.24e-2)" "potential prognostic unfavorable (6.63e-5)" "unprognostic (3.79e-1)" "unprognostic (3.09e-2)" "unprognostic (8.23e-2)" "unprognostic (2.53e-2)" "unprognostic (2.72e-3)" "unprognostic (1.86e-2)" "unprognostic (2.43e-1)" "unprognostic (1.82e-1)" "unprognostic (1.14e-2)" "unprognostic (2.55e-3)" "unprognostic (3.09e-2)" "unprognostic (4.79e-1)" "unprognostic (1.60e-2)" "unprognostic (5.32e-2)" SPINT2 "HAI-2, HAI2, Kop" ENSG00000167642 "Serine peptidase inhibitor, Kunitz type 2" O43291 19 38244035-38292615 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Enterocytes: 120.3" "Cell type enhanced" "Detected in many" "oligodendrocyte: 55.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Colon - Colon enterocytes, Heart muscle - Macrophages, Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011031, HPA011101, CAB018969, HPA074637" Approved Enhanced "Golgi apparatus,Vesicles" NA NA 13000 "Cluster 29: Non-specific - Unknown function" "Cluster 60: Stomach - Digestion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 16 "Golgi apparatus" Vesicles "CAB018969: , HPA011031: , HPA011101: , HPA074637: " "unprognostic (2.46e-2)" "unprognostic (1.23e-3)" "unprognostic (7.14e-2)" "potential prognostic unfavorable (3.40e-4)" "unprognostic (6.14e-2)" "unprognostic (3.56e-1)" "unprognostic (3.55e-3)" "unprognostic (2.70e-2)" "unprognostic (2.55e-2)" "unprognostic (3.10e-1)" "potential prognostic favorable (3.27e-4)" "unprognostic (1.44e-1)" "unprognostic (2.52e-1)" "unprognostic (5.94e-2)" "unprognostic (5.75e-2)" "unprognostic (1.92e-2)" "unprognostic (1.71e-1)" "unprognostic (1.49e-1)" "unprognostic (3.44e-3)" "unprognostic (2.21e-2)" "unprognostic (1.16e-1)" "unprognostic (1.61e-2)" "unprognostic (2.40e-1)" "unprognostic (1.85e-1)" "unprognostic (3.81e-1)" "unprognostic (9.07e-2)" "unprognostic (3.64e-1)" "unprognostic (2.62e-1)" "unprognostic (3.42e-2)" "unprognostic (9.68e-2)" "unprognostic (1.99e-2)" SPINT3 HKIB9 ENSG00000101446 "Serine peptidase inhibitor, Kunitz type 3" P49223 20 45512461-45515622 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 6 "epididymis: 4.5;seminal vesicle: 10.1" "Group enriched" "Detected in some" 4 "Endometrial luminal cells: 10.1;Epididymal principal cells: 18.5" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 14 "Bladder Urothelial Carcinoma (TCGA): 1.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA026852 Enhanced "Secreted in male reproductive system" "Enzyme inhibitor" NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" "HPA026852: " SPINT4 "C20orf137, dJ601O1.1" ENSG00000149651 "Serine peptidase inhibitor, Kunitz type 4" Q6UDR6 20 45722347-45725830 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 261 "epididymis: 263.2" "Cell type enriched" "Detected in some" 6 "Epididymal principal cells: 572.8" "Cell type enriched" "Detected in single" 4 "ependymal cell: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA046703 Enhanced "Secreted in male reproductive system" "Enzyme inhibitor" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" "HPA046703: " "unprognostic (2.67e-1)" SPIRE1 "KIAA1135, spir-1" ENSG00000134278 "Spire type actin nucleation factor 1" Q08AE8 18 12446512-12658107 "Predicted intracellular proteins" "Host-virus interaction, Immunity, Innate immunity, Protein transport, Transport" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 395.1;Late spermatids: 491.0;Renal connecting tubule cells: 616.6" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 48.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 83.4" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040737, HPA040942" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 17 "Nucleoplasm, Cytosol" "Plasma membrane" "HPA040737: , HPA040942: " "unprognostic (1.06e-2)" "unprognostic (1.80e-1)" "unprognostic (5.70e-2)" "unprognostic (1.13e-1)" "unprognostic (2.34e-1)" "unprognostic (2.05e-1)" "unprognostic (1.81e-2)" "unprognostic (4.31e-3)" "unprognostic (2.34e-2)" "potential prognostic unfavorable (3.47e-4)" "potential prognostic favorable (1.18e-4)" "unprognostic (1.11e-3)" "unprognostic (2.89e-1)" "unprognostic (2.05e-1)" "unprognostic (2.08e-2)" "unprognostic (2.86e-1)" "unprognostic (8.94e-2)" "unprognostic (1.94e-2)" "unprognostic (7.25e-2)" "unprognostic (1.45e-1)" "unprognostic (1.11e-1)" "unprognostic (4.14e-1)" "potential prognostic unfavorable (1.19e-4)" "unprognostic (4.95e-1)" "unprognostic (3.74e-1)" "unprognostic (4.04e-2)" "unprognostic (6.03e-2)" "potential prognostic unfavorable (4.77e-4)" "unprognostic (2.34e-1)" "unprognostic (2.07e-1)" "potential prognostic unfavorable (7.62e-4)" SPIRE2 "KIAA1832, spir-2" ENSG00000204991 "Spire type actin nucleation factor 2" Q8WWL2 16 89818179-89871319 "Predicted intracellular proteins" "Protein transport, Transport" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.9;pituitary gland: 21.0" "Cell type enhanced" "Detected in many" "Colonocytes: 97.2;Enteric stem cells: 95.2;Foveolar cells: 142.3;Goblet cells: 121.7;Paneth cells: 119.9;Papillary tip epithelial cells: 102.1;Prostatic club cells: 140.8;Prostatic hillock cells: 131.9;Somatotrophs: 214.2;Syncytiotrophoblasts: 147.9;Urothelial cells: 131.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Somatotropes, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041413, HPA049415" Uncertain Approved "Nucleoplasm,Vesicles,Intermediate filaments,Primary cilium" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 64: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 69: Urothelial cells - Basic cellular functions" 6 Nucleoplasm "Vesicles, Intermediate filaments, Primary cilium" "HPA041413: , HPA049415: " "unprognostic (4.60e-3)" "unprognostic (6.28e-2)" "unprognostic (1.39e-1)" "unprognostic (1.23e-1)" "unprognostic (4.71e-2)" "unprognostic (1.81e-1)" "unprognostic (4.18e-3)" "potential prognostic favorable (6.01e-4)" "unprognostic (4.50e-2)" "unprognostic (2.83e-3)" "unprognostic (7.15e-3)" "unprognostic (7.23e-2)" "unprognostic (1.16e-1)" "potential prognostic unfavorable (6.92e-4)" "unprognostic (5.71e-3)" "unprognostic (3.04e-1)" "unprognostic (2.13e-2)" "unprognostic (1.83e-1)" "unprognostic (4.38e-1)" "unprognostic (8.39e-2)" "unprognostic (1.20e-2)" "unprognostic (4.16e-2)" "unprognostic (4.53e-1)" "unprognostic (7.55e-3)" "unprognostic (4.33e-2)" "unprognostic (2.05e-1)" "unprognostic (2.87e-2)" "unprognostic (1.02e-2)" "unprognostic (5.49e-2)" "unprognostic (9.73e-3)" "unprognostic (1.80e-1)" SPN "CD43, GPL115, LEU-22, LSN" ENSG00000197471 Sialophorin P16150 16 29662979-29670876 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "bone marrow: 67.7;lung: 26.6;lymphoid tissue: 47.6" "Cell type enhanced" "Detected in some" "Erythrocyte progenitors: 5.8;Erythrocytes: 1.5;Hematopoietic stem cells: 2.4;Mast cells: 1.3;Megakaryocyte progenitors: 9.8;Megakaryocyte-Erythroid progenitors: 7.3;Monocyte progenitors: 2.1;Neutrophil progenitors: 2.7;NK-cells: 2.7;T-cells: 1.3;Thymocytes: 4.2" "Cell type enhanced" "Detected in single" "leukocyte: 1.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 218.5" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 185.3;Myeloma: 49.9" "Prostate - T-cells, Skin - Langerhans cells, Spleen - T-cells, Stomach - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB002666, HPA055244" Enhanced Approved "Plasma membrane" NA NA 6100 "Cluster 33: Non-specific - ATP binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 6: Non-specific - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 31 "Plasma membrane" "CAB002666: , HPA055244: " "unprognostic (1.56e-2)" "unprognostic (1.28e-2)" "unprognostic (2.02e-2)" "unprognostic (2.08e-1)" "unprognostic (3.64e-1)" "unprognostic (5.85e-2)" "unprognostic (1.35e-1)" "unprognostic (2.40e-1)" "unprognostic (1.50e-2)" "unprognostic (1.08e-1)" "potential prognostic favorable (9.85e-4)" "unprognostic (5.44e-2)" "unprognostic (1.08e-1)" "unprognostic (4.84e-2)" "unprognostic (2.42e-2)" "unprognostic (3.57e-3)" "unprognostic (3.70e-2)" "unprognostic (6.73e-2)" "unprognostic (2.16e-1)" "unprognostic (3.05e-1)" "unprognostic (2.78e-1)" "unprognostic (7.40e-2)" "unprognostic (2.55e-1)" "unprognostic (1.31e-1)" "unprognostic (8.46e-2)" "unprognostic (3.08e-1)" "unprognostic (1.34e-3)" "unprognostic (1.97e-2)" "unprognostic (2.70e-2)" "unprognostic (8.47e-2)" "unprognostic (4.74e-2)" SPNS1 "HSpin1, LAT, nrs, PP2030, SLC63A1, SPIN1, SPINL" ENSG00000169682 "Sphingolipid transporter 1 (putative)" Q9H2V7 16 28974221-28984548 "Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 15.1;Bergmann glia: 15.7;Brain excitatory neurons: 14.8;Brain inhibitory neurons: 12.9;Choroid plexus epithelial cells: 13.3;Distal convoluted tubule cells: 16.5;Ependymal cells: 9.9;Loop of henle epithelial cells: 13.7;Microglia: 17.3;Oligodendrocyte progenitor cells: 17.2;Oligodendrocytes: 16.9;Other brain neurons: 11.8;Papillary tip epithelial cells: 11.7;Podocytes: 13.4;Proximal tubule cells: 21.4;Renal collecting duct intercalated cells: 11.6;Renal collecting duct principal cells: 12.8;Renal connecting tubule cells: 15.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041995, HPA042988" Enhanced Approved "Nucleoli fibrillar center,Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 54: Non-specific - Transcription" "Cluster 102: Non-specific - Mixed function" 2 Vesicles "Nucleoli fibrillar center, Golgi apparatus, Cytosol" "HPA041995: , HPA042988: " "unprognostic (1.97e-2)" "unprognostic (1.40e-1)" "unprognostic (2.49e-1)" "unprognostic (1.23e-1)" "unprognostic (9.71e-3)" "unprognostic (3.96e-2)" "unprognostic (2.10e-1)" "unprognostic (1.80e-3)" "unprognostic (1.76e-2)" "unprognostic (1.34e-1)" "unprognostic (3.01e-2)" "unprognostic (1.98e-2)" "unprognostic (2.16e-2)" "potential prognostic unfavorable (1.92e-4)" "unprognostic (1.65e-3)" "unprognostic (6.17e-2)" "unprognostic (4.43e-3)" "unprognostic (1.90e-1)" "unprognostic (1.08e-1)" "unprognostic (1.13e-1)" "unprognostic (4.92e-2)" "unprognostic (4.09e-2)" "unprognostic (8.74e-3)" "potential prognostic unfavorable (8.70e-4)" "unprognostic (1.37e-1)" "unprognostic (1.36e-1)" "unprognostic (1.07e-1)" "unprognostic (4.24e-1)" "unprognostic (3.10e-1)" "unprognostic (9.24e-2)" "unprognostic (1.41e-2)" SPNS2 SLC63A2 ENSG00000183018 "Sphingolipid transporter 2" Q8IVW8 17 4498881-4539035 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 50.0" "Cell type enriched" "Detected in many" 4 "Esophageal apical cells: 627.4" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 174.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Endothelial cells, Lung - Endothelial cells, Pituitary gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Keratinocyte (granular), Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068717 Uncertain NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" "HPA068717: " "unprognostic (1.67e-1)" "unprognostic (4.71e-3)" "unprognostic (4.74e-3)" "unprognostic (9.79e-3)" "unprognostic (4.89e-2)" "unprognostic (3.07e-2)" "unprognostic (2.66e-1)" "unprognostic (2.25e-1)" "unprognostic (4.15e-2)" "potential prognostic favorable (2.09e-4)" "potential prognostic favorable (1.07e-7)" "unprognostic (1.16e-2)" "unprognostic (1.54e-1)" "unprognostic (2.89e-2)" "unprognostic (1.28e-2)" "unprognostic (1.73e-1)" "unprognostic (1.86e-1)" "unprognostic (7.11e-3)" "unprognostic (7.76e-2)" "potential prognostic unfavorable (4.65e-4)" "unprognostic (1.78e-1)" "unprognostic (4.21e-2)" "unprognostic (2.81e-1)" "unprognostic (9.97e-2)" "unprognostic (1.09e-2)" "unprognostic (2.67e-1)" "unprognostic (6.70e-2)" "unprognostic (3.98e-2)" "unprognostic (1.14e-1)" "unprognostic (9.95e-3)" "unprognostic (2.32e-3)" SPNS3 "MGC29671, SLC63A3" ENSG00000182557 "Sphingolipid transporter 3 (putative)" Q6ZMD2 17 4433940-4488208 "Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "bone marrow: 29.4" "Cell type enhanced" "Detected in many" "cDC: 31.6;Megakaryocytes: 49.5;Microglia: 22.8;Monocyte progenitors: 82.0;Neutrophil progenitors: 57.6;pDCs: 73.4;Platelets: 42.3;T-cells: 20.4;Thymocytes: 133.8" "Group enriched" "Detected in some" 13 "central nervous system macrophage: 29.2;leukocyte: 10.3" "Cancer enhanced" "Detected in some" "Kidney Renal Papillary Cell Carcinoma (TCGA): 1.7" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "eosinophil: 355.4;plasmacytoid DC: 127.9" "Group enriched" "Detected in many" 37 "dendritic cells: 127.9;granulocytes: 355.4" "Cancer enriched" "Detected in some" 5 "Leukemia: 40.9" "Prostate - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA023928 Uncertain NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 3 "HPA023928: " "unprognostic (5.87e-2)" "unprognostic (3.23e-2)" "unprognostic (1.34e-1)" "unprognostic (2.86e-1)" "potential prognostic favorable (1.44e-4)" SPO11 "CT35, SPATA43, TOPOVIA, TOPVIA" ENSG00000054796 "SPO11 initiator of meiotic double stranded breaks" Q9Y5K1 20 57329803-57343994 "Enzymes, Plasma proteins, Predicted intracellular proteins" Meiosis "DNA-binding, Isomerase, Topoisomerase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 79 "testis: 7.9" "Cell type enriched" "Detected in some" 9 "Early primary spermatocytes: 108.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 70: DU4475 - Unknown function" "Cluster 3: Early primary spermatocytes - Early meiosis" SPOCD1 "FLJ25348, PPP1R146" ENSG00000134668 "SPOC domain containing 1" Q6ZMY3 1 31790422-31816022 "Predicted intracellular proteins" "Differentiation, RNA-mediated gene silencing, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 10.6;testis: 9.4;urinary bladder: 8.9" "Group enriched" "Detected in some" 5 "Platelets: 184.9;Urothelial cells: 157.8" "Group enriched" "Detected in some" 4 "midbrain-derived inhibitory: 14.0;oligodendrocyte: 4.4" "Group enriched" "Detected in many" 6 "Bladder Urothelial Carcinoma (TCGA): 11.3;Glioblastoma Multiforme (TCGA): 43.7" "Region enhanced" "Detected in all" "thalamus: 24.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 31.3" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" "HPA031713, HPA031714, HPA031715" Enhanced Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 12: Non-specific - Vasculature" "Cluster 72: Neuronal - Signal transduction" "Cluster 69: Urothelial cells - Basic cellular functions" Cytosol "Nucleoplasm, Nucleoli" "HPA031713: , HPA031714: , HPA031715: " "unprognostic (1.43e-2)" "unprognostic (1.65e-1)" "unprognostic (3.68e-1)" "unprognostic (1.18e-1)" "unprognostic (5.51e-3)" "unprognostic (2.23e-1)" "unprognostic (4.64e-2)" "unprognostic (2.84e-1)" "unprognostic (1.61e-2)" "unprognostic (3.55e-1)" "unprognostic (2.18e-2)" "potential prognostic unfavorable (7.61e-4)" "unprognostic (4.79e-2)" "unprognostic (8.24e-3)" "unprognostic (4.48e-2)" "unprognostic (2.77e-2)" "unprognostic (9.43e-2)" "unprognostic (8.29e-3)" "unprognostic (4.41e-2)" "unprognostic (2.12e-1)" "unprognostic (1.61e-2)" "unprognostic (1.05e-2)" "unprognostic (4.33e-2)" SPOCK1 "SPOCK, testican-1, TIC1" ENSG00000152377 "SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1" Q08629 5 136975298-137598379 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 173.0" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 589.3;Brain inhibitory neurons: 436.6;Müller glia: 693.6;Oligodendrocyte progenitor cells: 466.0;Oligodendrocytes: 1142.6;Podocytes: 2117.2;Prostatic glandular cells: 541.9;Retinal amacrine cells: 441.3;Sertoli cells: 657.8" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 6 "Prostate Adenocarcinoma (TCGA): 176.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 140.3;thyroid cancer: 129.8" "Lung - Fibroblasts_2, Minor Salivary Gland - Macrophages, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007450, HPA026770" Uncertain Approved Vesicles "Secreted to blood" "No annotated function" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 27: Cerebellum - Synaptic function" "Cluster 11: White matter - Signal transduction" "Cluster 15: Kidney cancer - Membrane components" "Cluster 108: Fibroblasts - ECM organization" 2 Vesicles "HPA007450: , HPA026770: " "unprognostic (1.53e-3)" "unprognostic (2.36e-1)" "unprognostic (1.28e-1)" "unprognostic (2.62e-2)" "unprognostic (3.41e-3)" "unprognostic (3.29e-2)" "unprognostic (1.43e-1)" "unprognostic (8.90e-3)" "potential prognostic unfavorable (3.55e-5)" "unprognostic (2.52e-3)" "unprognostic (1.16e-2)" "unprognostic (4.54e-3)" "unprognostic (9.80e-2)" "unprognostic (2.53e-3)" "unprognostic (2.16e-1)" "potential prognostic unfavorable (5.04e-5)" "unprognostic (9.26e-2)" "unprognostic (2.01e-1)" "unprognostic (3.33e-2)" "unprognostic (2.27e-3)" "potential prognostic unfavorable (4.09e-5)" "unprognostic (1.31e-3)" "unprognostic (2.07e-1)" "unprognostic (1.63e-1)" "unprognostic (4.01e-3)" "unprognostic (2.77e-3)" "unprognostic (7.36e-3)" "potential prognostic unfavorable (2.58e-4)" "unprognostic (1.60e-1)" "unprognostic (3.07e-1)" "unprognostic (5.47e-2)" SPOCK2 "KIAA0275, testican-2" ENSG00000107742 "SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2" Q92563 10 72059034-72089032 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 218.8;lymphoid tissue: 106.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 817.1;Bergmann glia: 190.6;Brain inhibitory neurons: 115.8;Innate lymphoid cells: 189.5;Other brain neurons: 106.4;Podocytes: 501.7;Retinal bipolar cells: 103.1;Retinal ganglion cells: 112.0;T-cells: 239.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 45.9;MAIT T-cell: 79.8;memory CD4 T-cell: 46.3;memory CD8 T-cell: 36.1;naive CD4 T-cell: 37.9;naive CD8 T-cell: 39.9;T-reg: 63.3" "Lineage enriched" "Detected in many" 8 "T-cells: 79.8" "Cancer enhanced" "Detected in many" "ovarian cancer: 140.6;Uterine cancer: 69.7" "Colon - Colon enteroendocrine cells, Kidney - Podocytes, Liver - T-cells, Lung - Alveolar cells type 1, Minor Salivary Gland - T-cells, Pituitary gland - Gonadotropes, Prostate - T-cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044605 Enhanced "Secreted to blood" "No annotated function" NA NA 240000 "Cluster 11: T-cells - Unknown function" "Cluster 27: Cerebellum - Synaptic function" "Cluster 49: Hindbrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 9: T-cells - Adaptive immunity: Regulation" 1 "HPA044605: " "unprognostic (1.62e-2)" "potential prognostic favorable (8.92e-4)" "unprognostic (2.07e-2)" "unprognostic (3.41e-3)" "unprognostic (1.16e-2)" "unprognostic (2.77e-1)" "unprognostic (1.02e-1)" "unprognostic (1.48e-1)" "potential prognostic favorable (3.56e-5)" "unprognostic (7.86e-2)" "potential prognostic favorable (3.46e-5)" "unprognostic (1.79e-3)" "unprognostic (1.79e-1)" "unprognostic (5.53e-2)" "unprognostic (1.36e-1)" "unprognostic (9.35e-3)" "unprognostic (3.23e-3)" "unprognostic (1.42e-2)" "unprognostic (2.08e-1)" "potential prognostic unfavorable (3.24e-4)" "unprognostic (1.35e-1)" "unprognostic (9.49e-3)" "unprognostic (2.37e-3)" "unprognostic (1.58e-1)" "unprognostic (2.90e-2)" "unprognostic (2.95e-2)" "unprognostic (3.80e-3)" "unprognostic (1.27e-1)" "unprognostic (7.19e-2)" "unprognostic (5.17e-3)" "unprognostic (9.28e-2)" SPOCK3 testican-3 ENSG00000196104 "SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3" Q9BQ16 4 166733384-167234796 "Predicted intracellular proteins, Predicted secreted proteins" "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 127.4;parathyroid gland: 164.7;prostate: 69.3" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 723.3;Bergmann glia: 1252.1;Brain inhibitory neurons: 938.7;Oligodendrocyte progenitor cells: 495.8;Oligodendrocytes: 1828.7;Other brain neurons: 447.1;Retinal amacrine cells: 763.0;Retinal ganglion cells: 405.6" "Cell type enhanced" "Detected in all" "MGE interneuron: 2247.9;oligodendrocyte: 2418.0" "Group enriched" "Detected in many" 4 "Bladder Urothelial Carcinoma (TCGA): 5.1;Glioblastoma Multiforme (TCGA): 9.6;Lung Squamous Cell Carcinoma (TCGA): 4.3;Prostate Adenocarcinoma (TCGA): 17.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.2;myeloid DC: 1.8" "Group enriched" "Detected in many" 12 "dendritic cells: 1.8;monocytes: 1.2" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 17.9;Rhabdoid: 26.3" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Prostate - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" "Enzyme inhibitor" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 73: Brain - Neuronal signaling" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 80: Oligodendrocytes - Myelination" "unprognostic (3.38e-2)" "unprognostic (2.36e-2)" "unprognostic (1.20e-1)" "unprognostic (1.51e-1)" "unprognostic (4.38e-2)" "unprognostic (2.06e-2)" "unprognostic (1.27e-1)" "unprognostic (2.21e-2)" "unprognostic (3.09e-2)" "unprognostic (1.02e-1)" "unprognostic (3.09e-1)" "unprognostic (1.81e-1)" "unprognostic (2.12e-1)" "unprognostic (3.09e-3)" "unprognostic (4.30e-2)" "unprognostic (9.15e-2)" "unprognostic (2.62e-1)" "unprognostic (2.53e-2)" SPON1 "f-spondin, KIAA0762" ENSG00000262655 "Spondin 1" Q9HCB6 11 13962723-14268133 "Essential proteins, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 291.1;Astrocytes: 546.2;Bergmann glia: 219.4;Corticotrophs: 161.9;Endometrial luminal cells: 161.5;Endometrial stromal cells: 202.7;Epicardial cells: 291.1;Fibroblasts: 198.0;Müller glia: 558.9;Pituicytes/FSCs: 231.3;Thymocytes: 360.8" "Cell type enhanced" "Detected in all" "astrocyte: 662.9;hippocampal dentate gyrus: 545.6" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 269.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "MAIT T-cell: 3.3" "Lineage enriched" "Detected in single" 33 "T-cells: 3.3" "Group enriched" "Detected in many" 8 "ovarian cancer: 127.8;Uterine cancer: 91.3" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Fibroblasts, Breast - Adipocytes (Breast), Kidney - Fibroblasts, Minor Salivary Gland - Macrophages, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038583, HPA077546" Uncertain Approved Vesicles "Secreted to blood" "Cell adhesion" NA No 11500000 49000000 "Cluster 1: T-cells - Unknown function" "Cluster 13: Lung - Secretion" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 108: Fibroblasts - ECM organization" 4 Vesicles "HPA038583: , HPA077546: " "unprognostic (1.57e-2)" "unprognostic (3.17e-1)" "unprognostic (1.07e-1)" "unprognostic (1.85e-3)" "unprognostic (8.95e-2)" "unprognostic (1.42e-1)" "unprognostic (1.16e-1)" "unprognostic (5.41e-2)" "unprognostic (1.07e-3)" "unprognostic (6.60e-3)" "potential prognostic favorable (3.42e-4)" "unprognostic (4.49e-2)" "unprognostic (9.94e-2)" "unprognostic (4.10e-1)" "unprognostic (1.14e-2)" "unprognostic (4.80e-2)" "unprognostic (2.45e-2)" "unprognostic (7.71e-2)" "unprognostic (1.45e-1)" "unprognostic (2.59e-2)" "unprognostic (5.30e-2)" "unprognostic (1.32e-1)" "unprognostic (2.14e-2)" "unprognostic (1.35e-1)" "unprognostic (3.92e-2)" "unprognostic (2.90e-1)" SPON2 DIL1 ENSG00000159674 "Spondin 2" Q9BUD6 4 1166932-1208962 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 186.3" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 928.1;Endometrial stromal cells: 208.7;Extravillous trophoblasts: 565.6;Fibroblasts: 190.2;Hepatic stellate cells: 206.6;NK-cells: 357.1;Thymocytes: 213.4" "Cell type enhanced" "Detected in all" "leukocyte: 161.0" "Cancer enriched" "Detected in all" 5 "Prostate Adenocarcinoma (TCGA): 1231.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 256.9" "Lineage enriched" "Detected in all" 5 "T-cells: 256.9" "Cancer enriched" "Detected in many" 9 "prostate cancer: 639.9" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Adrenal gland - Fibroblasts, Breast - Fibroblasts, Pituitary gland - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA040170, HPA066095" Approved Approved Vesicles "Secreted to blood" Immunity NA NA 1600000 "Cluster 1: T-cells - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 60: Prostate cancer - Unknown function" "Cluster 108: Fibroblasts - ECM organization" 3 Vesicles "HPA040170: , HPA066095: " "unprognostic (5.69e-2)" "unprognostic (9.16e-2)" "unprognostic (7.16e-3)" "unprognostic (1.68e-1)" "unprognostic (1.04e-2)" "unprognostic (9.90e-2)" "unprognostic (4.38e-2)" "unprognostic (8.95e-3)" "unprognostic (1.18e-1)" "unprognostic (3.10e-1)" "potential prognostic unfavorable (9.91e-6)" "unprognostic (2.25e-1)" "potential prognostic favorable (4.93e-4)" "unprognostic (2.89e-3)" "unprognostic (1.74e-2)" "unprognostic (2.34e-3)" "unprognostic (3.83e-3)" "unprognostic (1.27e-2)" "unprognostic (8.49e-3)" "unprognostic (1.07e-1)" "unprognostic (5.77e-2)" "unprognostic (1.12e-1)" "unprognostic (1.36e-1)" "unprognostic (7.43e-2)" "unprognostic (3.12e-1)" "unprognostic (4.30e-3)" "unprognostic (3.33e-1)" "unprognostic (7.44e-3)" "unprognostic (2.32e-1)" "unprognostic (3.11e-2)" "unprognostic (4.14e-1)" SPOP "BTBD32, TEF2" ENSG00000121067 "Speckle type BTB/POZ protein" O43791 17 49598884-49678163 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Cancer-related genes, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Myonuclei: 312.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 31: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 62: Smooth muscle cells - Muscle contraction" 126 "unprognostic (1.25e-1)" "unprognostic (1.79e-1)" "unprognostic (9.44e-2)" "unprognostic (3.28e-1)" "unprognostic (2.46e-1)" "unprognostic (5.93e-2)" "unprognostic (1.81e-1)" "unprognostic (2.57e-1)" "unprognostic (1.04e-1)" "potential prognostic unfavorable (8.51e-4)" "potential prognostic favorable (7.25e-6)" "unprognostic (1.07e-2)" "unprognostic (5.80e-2)" "potential prognostic unfavorable (8.23e-4)" "unprognostic (6.93e-2)" "unprognostic (1.39e-1)" "unprognostic (1.63e-1)" "unprognostic (1.13e-1)" "unprognostic (1.28e-1)" "unprognostic (9.36e-3)" "unprognostic (1.81e-2)" "unprognostic (2.56e-2)" "unprognostic (5.53e-2)" "unprognostic (2.26e-2)" "unprognostic (1.75e-1)" "unprognostic (8.67e-3)" "unprognostic (5.14e-2)" "unprognostic (1.48e-1)" "unprognostic (2.40e-2)" "unprognostic (1.47e-1)" "unprognostic (9.33e-2)" SPOPL BTBD33 ENSG00000144228 "Speckle type BTB/POZ protein like" Q6IQ16 2 138501770-138573547 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophil progenitors: 297.8;Neutrophils: 610.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 5.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034687 Uncertain Approved Vesicles NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" 9 Vesicles "HPA034687: " "unprognostic (2.38e-1)" "unprognostic (5.68e-3)" "unprognostic (6.48e-2)" "unprognostic (2.68e-2)" "unprognostic (5.10e-2)" "unprognostic (7.78e-2)" "unprognostic (1.53e-1)" "unprognostic (1.48e-1)" "unprognostic (7.64e-2)" "unprognostic (6.74e-2)" "potential prognostic favorable (4.76e-8)" "unprognostic (1.27e-3)" "unprognostic (2.41e-1)" "unprognostic (5.20e-2)" "unprognostic (1.81e-1)" "unprognostic (1.13e-1)" "unprognostic (2.79e-2)" "unprognostic (2.14e-1)" "unprognostic (2.44e-1)" "unprognostic (1.08e-1)" "unprognostic (1.09e-2)" "unprognostic (8.19e-3)" "unprognostic (1.41e-1)" "unprognostic (7.99e-2)" "unprognostic (3.23e-1)" "unprognostic (1.08e-1)" "unprognostic (2.65e-1)" "unprognostic (6.24e-2)" "unprognostic (1.32e-1)" "unprognostic (2.64e-2)" "unprognostic (2.73e-2)" SPOUT1 "C9orf114, CENP-32, HSPC109" ENSG00000198917 "SPOUT domain containing methyltransferase 1" Q5T280 9 128819651-128829794 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, rRNA processing" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 20.5;Bergmann glia: 25.9;Brain excitatory neurons: 7.2;Brain inhibitory neurons: 9.4;Choroid plexus epithelial cells: 5.7;Ependymal cells: 9.3;Loop of henle epithelial cells: 5.3;Microglia: 8.3;Oligodendrocyte progenitor cells: 9.2;Oligodendrocytes: 11.2;Other brain neurons: 8.4;Papillary tip epithelial cells: 9.3;Podocytes: 8.8;Proximal tubule cells: 7.6;Renal collecting duct principal cells: 5.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076946 Approved NA NA "Cluster 1: T-cells - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 28: Astrocytes - Homeostasis & neuron support" 7 "HPA076946: " "unprognostic (8.53e-2)" "unprognostic (2.39e-1)" "unprognostic (1.83e-3)" "unprognostic (6.39e-3)" "unprognostic (7.62e-3)" "unprognostic (2.33e-1)" "potential prognostic favorable (2.95e-7)" "unprognostic (1.91e-1)" "unprognostic (8.76e-2)" "unprognostic (3.80e-2)" "unprognostic (2.47e-1)" "unprognostic (1.72e-3)" "unprognostic (3.31e-3)" "unprognostic (6.22e-2)" "unprognostic (2.43e-2)" "unprognostic (1.44e-1)" "unprognostic (2.52e-2)" "unprognostic (5.91e-2)" "unprognostic (9.55e-2)" "unprognostic (1.55e-2)" "unprognostic (1.63e-1)" "unprognostic (4.03e-1)" "unprognostic (1.57e-1)" "unprognostic (1.13e-1)" "unprognostic (5.66e-2)" "unprognostic (1.50e-1)" "unprognostic (3.78e-1)" "unprognostic (2.10e-1)" "potential prognostic favorable (1.74e-4)" SPP1 "BNSP, BSPI, ETA-1, OPN" ENSG00000118785 "Secreted phosphoprotein 1" P10451 4 87975667-87983532 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Biomineralization, Cell adhesion" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 1840.1;gallbladder: 2283.6;kidney: 3270.9;placenta: 2626.4" "Cell type enriched" "Detected in many" 5 "Hofbauer cells: 104895.0" "Group enriched" "Detected in all" 8 "central nervous system macrophage: 1317.0;oligodendrocyte: 901.7" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 4384.1;Kidney Renal Papillary Cell Carcinoma (TCGA): 6722.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 11 "neutrophil: 26.6" "Lineage enriched" "Detected in single" 266 "granulocytes: 26.6" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 4186.2;Kidney cancer: 2365.8" "Adipose subcutaneous - Macrophages, Heart muscle - Macrophages" "Region enhanced" "Detected in all" "pons and medulla: 317.0" "Low region specificity" "Detected in all" "HPA027540, HPA027541" Enhanced Enhanced "Golgi apparatus" "Secreted to blood" Cytokine NA NA 114000000 50000000 "Cluster 4: Neutrophils - Degranulation" "Cluster 72: Kidney - Transmembrane transport" "Cluster 30: White matter - Myelination" "Cluster 15: Kidney cancer - Membrane components" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 12 "Golgi apparatus" "HPA027540: , HPA027541: " "unprognostic (1.88e-1)" "unprognostic (4.23e-1)" "unprognostic (1.32e-2)" "potential prognostic unfavorable (2.71e-4)" "unprognostic (1.56e-2)" "unprognostic (6.37e-2)" "unprognostic (2.20e-2)" "unprognostic (3.25e-2)" "unprognostic (4.93e-3)" "unprognostic (7.62e-2)" "unprognostic (2.31e-2)" "unprognostic (2.84e-1)" "unprognostic (2.50e-1)" "potential prognostic unfavorable (2.20e-6)" "unprognostic (4.18e-3)" "unprognostic (1.20e-2)" "potential prognostic unfavorable (3.58e-5)" "unprognostic (2.72e-2)" "unprognostic (2.73e-3)" "unprognostic (3.37e-3)" "unprognostic (1.47e-2)" "potential prognostic unfavorable (1.55e-4)" "unprognostic (3.51e-3)" "unprognostic (1.69e-2)" "unprognostic (6.47e-3)" "unprognostic (1.09e-1)" "unprognostic (2.30e-1)" "unprognostic (9.42e-2)" "unprognostic (1.93e-1)" "unprognostic (2.13e-1)" "unprognostic (5.06e-2)" SPP2 SPP24 ENSG00000072080 "Secreted phosphoprotein 2" Q13103 2 234050679-234077134 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 4391 "liver: 484.9" "Cell type enriched" "Detected in some" 59 "Hepatocytes: 358.8" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 54 "Liver Hepatocellular Carcinoma (TCGA): 110.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "Secreted to blood" "No annotated function" NA NA 280000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 5: Rhabdoid - Unknown function" "Cluster 93: Hepatocytes - Bile production & excretion" "potential prognostic favorable (9.13e-7)" "unprognostic (9.08e-3)" "unprognostic (2.43e-2)" "unprognostic (3.50e-2)" "unprognostic (9.88e-2)" "unprognostic (2.98e-3)" SPPL2A "IMP3, PSL2" ENSG00000138600 "Signal peptide peptidase like 2A" Q8TCT8 15 50702266-50765948 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Myonuclei: 740.0;Neutrophils: 414.2;Thymic myoid cells: 788.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036062, HPA067304" Enhanced Supported Vesicles NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 8: Immune cells - Immune response" "Cluster 58: Non-specific - Nuclear processes" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 2 Vesicles "HPA036062: , HPA067304: " "unprognostic (1.56e-1)" "unprognostic (1.20e-2)" "unprognostic (6.34e-2)" "unprognostic (1.00e-1)" "unprognostic (8.73e-2)" "unprognostic (5.66e-2)" "unprognostic (4.29e-1)" "potential prognostic unfavorable (4.98e-4)" "unprognostic (1.84e-1)" "unprognostic (1.71e-2)" "potential prognostic favorable (3.19e-5)" "unprognostic (9.27e-2)" "unprognostic (2.06e-1)" "unprognostic (1.59e-1)" "unprognostic (1.08e-1)" "unprognostic (2.44e-1)" "unprognostic (6.54e-2)" "unprognostic (9.89e-2)" "unprognostic (9.62e-2)" "unprognostic (9.49e-2)" "unprognostic (9.30e-2)" "unprognostic (2.65e-2)" "unprognostic (1.11e-1)" "unprognostic (1.69e-1)" "unprognostic (1.71e-2)" "unprognostic (4.17e-2)" "unprognostic (2.82e-2)" "unprognostic (1.27e-1)" "unprognostic (6.80e-2)" "unprognostic (5.89e-2)" "unprognostic (1.34e-1)" SPPL2B "IMP4, KIAA1532, PSL1" ENSG00000005206 "Signal peptide peptidase like 2B" Q8TCT7 19 2328615-2355095 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 168.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen), Stomach - Gastric mucous cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005592, HPA039292" Approved Approved "Nucleoplasm,Plasma membrane,Centrosome" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 67: Testis - Mixed function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 23: Non-specific - Transcription" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 3 "Nucleoplasm, Plasma membrane" Centrosome "CAB005592: , HPA039292: " "unprognostic (9.64e-2)" "unprognostic (3.72e-2)" "unprognostic (8.78e-2)" "unprognostic (4.50e-1)" "unprognostic (5.66e-2)" "unprognostic (2.60e-2)" "unprognostic (2.15e-1)" "unprognostic (4.66e-1)" "unprognostic (1.20e-2)" "unprognostic (3.07e-2)" "unprognostic (4.24e-2)" "unprognostic (6.47e-2)" "unprognostic (1.67e-2)" "unprognostic (3.14e-1)" "unprognostic (2.52e-1)" "unprognostic (1.04e-1)" "unprognostic (3.90e-1)" "unprognostic (3.38e-2)" "unprognostic (4.68e-2)" "unprognostic (2.61e-2)" "unprognostic (1.09e-2)" "unprognostic (3.96e-3)" "unprognostic (1.60e-1)" "unprognostic (4.87e-2)" "unprognostic (9.48e-3)" "unprognostic (1.91e-1)" "unprognostic (5.79e-2)" "unprognostic (5.27e-2)" "unprognostic (8.67e-2)" "unprognostic (7.21e-2)" "unprognostic (1.55e-2)" SPPL2C IMP5 ENSG00000185294 "Signal peptide peptidase like 2C" Q8IUH8 17 45844881-45847067 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "testis: 35.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA077339 Supported NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 2 "HPA077339: " SPPL3 "DKFZP586C1324, IMP2, MGC126674, MGC126676, MGC90402, PSL4" ENSG00000157837 "Signal peptide peptidase like 3" Q8TCT6 12 120762510-120904358 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Spleen - Endothelial cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004194, HPA059958" Uncertain Supported "Vesicles,Plasma membrane" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 61: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 85: Squamous epithelial cells - Keratinization" 2 "Vesicles, Plasma membrane" "HPA004194: , HPA059958: " "unprognostic (1.19e-1)" "unprognostic (5.99e-3)" "unprognostic (1.18e-1)" "unprognostic (2.77e-1)" "unprognostic (1.96e-1)" "unprognostic (1.71e-1)" "unprognostic (1.92e-1)" "unprognostic (2.25e-1)" "unprognostic (1.61e-2)" "unprognostic (2.09e-1)" "potential prognostic favorable (6.02e-6)" "unprognostic (1.10e-2)" "unprognostic (8.93e-2)" "validated prognostic unfavorable (4.69e-5)" "validated prognostic unfavorable (1.86e-4)" "unprognostic (1.10e-2)" "unprognostic (1.56e-1)" "unprognostic (7.77e-2)" "unprognostic (7.90e-2)" "unprognostic (2.66e-2)" "unprognostic (2.30e-3)" "unprognostic (1.92e-1)" "unprognostic (6.24e-3)" "unprognostic (1.42e-1)" "unprognostic (2.44e-1)" "unprognostic (1.44e-1)" "unprognostic (1.51e-1)" "unprognostic (2.88e-1)" "unprognostic (2.74e-1)" "unprognostic (1.71e-1)" "unprognostic (1.24e-1)" SPR SDR38C1 ENSG00000116096 "Sepiapterin reductase" P35270 2 72887382-72892158 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant, Dystonia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Colonocytes: 83.7;Enteric transient amplifying cells: 60.5;Enterocytes: 60.5;Epididymal principal cells: 56.8;Esophageal basal cells: 55.3;Fallopian tube ciliated cells: 59.8;Hepatocytes: 69.1;Hofbauer cells: 66.9;Oocytes: 73.7;Parietal cells: 67.2" "Cell type enhanced" "Detected in many" "ependymal cell: 6.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "classical monocyte: 8.3;intermediate monocyte: 2.4;myeloid DC: 8.9" "Group enriched" "Detected in many" 11 "dendritic cells: 8.9;monocytes: 8.3" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039505 Uncertain Supported Nucleoplasm,Cytosol NA NA 55000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 70: Non-specific - Protein processing" "Cluster 44: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 1 "Nucleoplasm, Cytosol" "HPA039505: " "unprognostic (2.06e-1)" "unprognostic (9.06e-2)" "unprognostic (3.74e-2)" "unprognostic (4.23e-3)" "unprognostic (2.35e-2)" "unprognostic (2.60e-1)" "unprognostic (1.29e-3)" "unprognostic (8.96e-2)" "unprognostic (6.23e-3)" "unprognostic (5.79e-2)" "unprognostic (3.66e-2)" "unprognostic (1.66e-1)" "unprognostic (4.94e-2)" "unprognostic (6.87e-2)" "unprognostic (2.00e-2)" "unprognostic (1.24e-2)" "unprognostic (3.11e-1)" "unprognostic (6.19e-2)" "unprognostic (1.52e-1)" "unprognostic (1.06e-1)" "unprognostic (6.11e-2)" "unprognostic (4.66e-2)" "unprognostic (1.10e-2)" "unprognostic (9.84e-2)" "unprognostic (2.61e-1)" "unprognostic (6.86e-3)" "unprognostic (3.91e-2)" "unprognostic (2.12e-2)" "unprognostic (1.54e-1)" "unprognostic (3.07e-3)" "unprognostic (5.01e-2)" SPRED1 "FLJ33903, PPP1R147" ENSG00000166068 "Sprouty related EVH1 domain containing 1" Q7Z699 15 38252836-38357249 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bergmann glia: 335.7;Hofbauer cells: 384.6;Macrophages: 404.7;Microglia: 698.3;Oligodendrocyte progenitor cells: 395.3" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 907.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.4" "Lineage enriched" "Detected in single" 4 "monocytes: 1.4" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042193, HPA061805" Approved Supported Nucleoplasm NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 73: Brain - Neuronal signaling" "Cluster 7: Non-specific - Ribosome" "Cluster 3: Rhabdoid - Membrane components" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 315 Nucleoplasm "HPA042193: , HPA061805: " "unprognostic (2.94e-2)" "unprognostic (1.60e-1)" "unprognostic (2.47e-1)" "unprognostic (1.63e-2)" "unprognostic (1.47e-1)" "unprognostic (1.14e-1)" "unprognostic (1.68e-1)" "unprognostic (3.74e-3)" "unprognostic (1.62e-1)" "unprognostic (1.54e-1)" "potential prognostic favorable (5.70e-5)" "unprognostic (5.20e-3)" "unprognostic (4.81e-2)" "potential prognostic unfavorable (3.78e-4)" "unprognostic (1.18e-1)" "unprognostic (1.32e-1)" "unprognostic (1.45e-2)" "unprognostic (3.06e-2)" "unprognostic (3.15e-1)" "unprognostic (4.77e-3)" "unprognostic (1.54e-3)" "unprognostic (1.42e-2)" "unprognostic (3.07e-2)" "unprognostic (9.06e-2)" "unprognostic (3.69e-1)" "unprognostic (1.06e-2)" "unprognostic (7.43e-2)" "potential prognostic unfavorable (2.63e-4)" "unprognostic (1.71e-1)" "unprognostic (6.58e-2)" "unprognostic (3.07e-1)" SPRED2 "FLJ21897, FLJ31917, Spred-2" ENSG00000198369 "Sprouty related EVH1 domain containing 2" Q7Z698 2 65310851-65432637 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "NK-cell: 1.9;plasmacytoid DC: 4.3" "Group enriched" "Detected in many" 4 "dendritic cells: 4.3;NK-cells: 1.9" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038256, HPA064394" Approved Uncertain Nucleoplasm,Cytosol NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 53: Neurons - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 54 Nucleoplasm Cytosol "HPA038256: , HPA064394: " "unprognostic (6.20e-2)" "unprognostic (1.46e-1)" "unprognostic (1.32e-1)" "unprognostic (1.14e-2)" "unprognostic (5.46e-2)" "unprognostic (8.84e-3)" "unprognostic (1.10e-1)" "unprognostic (2.23e-3)" "unprognostic (1.10e-1)" "unprognostic (3.92e-2)" "potential prognostic favorable (1.92e-5)" "unprognostic (1.72e-3)" "unprognostic (6.23e-3)" "unprognostic (3.18e-2)" "unprognostic (2.50e-1)" "unprognostic (1.03e-1)" "unprognostic (1.96e-2)" "unprognostic (5.12e-2)" "unprognostic (1.65e-2)" "unprognostic (1.10e-1)" "unprognostic (1.71e-2)" "unprognostic (3.08e-2)" "unprognostic (2.32e-2)" "unprognostic (3.78e-2)" "unprognostic (1.19e-1)" "unprognostic (5.94e-2)" "unprognostic (2.60e-1)" "unprognostic (7.32e-2)" "unprognostic (6.64e-2)" "unprognostic (3.02e-2)" "unprognostic (2.93e-1)" SPRED3 ENSG00000188766 "Sprouty related EVH1 domain containing 3" Q2MJR0 19 38388421-38399587 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.5" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 10.6;Brain excitatory neurons: 10.4;Brain inhibitory neurons: 11.2;Lactotrophs: 12.0;Neuroendocrine cells: 27.0;Oligodendrocyte progenitor cells: 12.1;Other brain neurons: 16.1;Pancreatic islet cells: 31.1;Pituicytes/FSCs: 12.9;Retinal amacrine cells: 10.4" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 7.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071521 Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" "Nucleoplasm, Plasma membrane" "HPA071521: " "unprognostic (9.27e-2)" "unprognostic (2.24e-1)" "unprognostic (1.65e-1)" "unprognostic (5.67e-3)" "unprognostic (4.62e-2)" "unprognostic (3.55e-2)" "unprognostic (5.69e-2)" "unprognostic (3.86e-2)" "unprognostic (3.55e-2)" "unprognostic (1.05e-3)" "unprognostic (3.46e-3)" "unprognostic (7.79e-2)" "unprognostic (1.11e-2)" "unprognostic (2.75e-2)" "unprognostic (2.03e-3)" "unprognostic (2.96e-2)" "unprognostic (7.40e-2)" "unprognostic (6.04e-3)" "unprognostic (1.99e-1)" "unprognostic (4.16e-3)" "unprognostic (2.72e-2)" SPRING1 "C12orf49, FLJ21415, LUR1, POST1, SPRING" ENSG00000111412 "SREBF pathway regulator in golgi 1" Q9H741 12 116710171-116738070 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 35.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 213.5;Endometrial glandular cells: 132.4;Parietal cells: 130.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026905 Uncertain NA NA 130000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 33: Thyroid gland - Tissue development" "Cluster 45: Non-specific - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 51: Secretory epithelial cells - Mixed function" 27 "HPA026905: " "unprognostic (7.64e-2)" "unprognostic (2.94e-3)" "unprognostic (1.65e-2)" "unprognostic (2.95e-2)" "unprognostic (1.09e-1)" "unprognostic (6.47e-2)" "unprognostic (8.80e-2)" "unprognostic (1.44e-1)" "potential prognostic unfavorable (1.93e-4)" "potential prognostic favorable (1.18e-6)" "unprognostic (1.63e-3)" "unprognostic (1.18e-3)" "potential prognostic unfavorable (1.39e-4)" "unprognostic (9.10e-2)" "unprognostic (4.47e-1)" "unprognostic (1.43e-2)" "unprognostic (4.33e-2)" "unprognostic (8.49e-3)" "unprognostic (1.71e-3)" "unprognostic (2.15e-1)" "unprognostic (2.97e-2)" "unprognostic (2.44e-1)" "unprognostic (6.59e-2)" "unprognostic (5.99e-3)" "unprognostic (6.01e-2)" "unprognostic (3.04e-1)" "unprognostic (2.75e-1)" "unprognostic (2.78e-1)" "unprognostic (1.15e-1)" SPRN "bA108K14.1, FLJ41197, Shadoo" ENSG00000203772 "Shadow of prion protein" Q5BIV9 10 133420666-133424625 "Predicted intracellular proteins, Transporters" Prion "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 12.6;liver: 7.3" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 8.5;Brain inhibitory neurons: 7.3;Cardiomyocytes: 4.0;Epicardial cells: 2.3;Neuroendocrine cells: 1.9;Oligodendrocyte progenitor cells: 7.6;Other brain neurons: 5.8;Retinal amacrine cells: 9.5" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Glioblastoma Multiforme (TCGA): 1.5;Prostate Adenocarcinoma (TCGA): 3.6;Uterine Corpus Endometrial Carcinoma (TCGA): 5.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" Other NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" "unprognostic (3.50e-2)" "unprognostic (1.08e-1)" "unprognostic (1.74e-1)" "unprognostic (2.60e-2)" "unprognostic (1.56e-1)" "unprognostic (2.76e-2)" "unprognostic (4.41e-3)" "unprognostic (2.51e-2)" "unprognostic (9.77e-2)" SPRR1A ENSG00000169474 "Small proline rich protein 1A" P35321 1 152984081-152985814 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 1194.2;esophagus: 3332.0;vagina: 1903.3" "Cell type enriched" "Detected in some" 9 "Esophageal apical cells: 97189.8" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "Head and Neck Squamous Cell Carcinoma (TCGA): 6660.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Esophageal cancer: 48.8;head and neck cancer: 100.2" CAB011237 Enhanced NA NA 610000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 4 "CAB011237: " "unprognostic (4.97e-2)" "unprognostic (5.81e-2)" "unprognostic (8.81e-2)" "unprognostic (2.49e-1)" "unprognostic (1.95e-1)" "unprognostic (2.72e-2)" "unprognostic (4.39e-2)" "unprognostic (1.75e-2)" "unprognostic (1.25e-1)" "unprognostic (2.64e-2)" "unprognostic (3.02e-1)" "unprognostic (5.48e-2)" "potential prognostic unfavorable (1.50e-4)" "unprognostic (2.87e-1)" "unprognostic (1.24e-1)" "unprognostic (3.53e-1)" "unprognostic (7.93e-2)" "unprognostic (2.81e-1)" "unprognostic (4.51e-1)" SPRR1B "GADD33, SPRR1" ENSG00000169469 "Small proline rich protein 1B" P22528 1 153031203-153032900 "Cancer-related genes, Essential proteins, Predicted intracellular proteins" Keratinization "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 1541.1;esophagus: 2176.6;vagina: 1767.0" "Cell type enriched" "Detected in some" 4 "Esophageal apical cells: 37246.9" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "Head and Neck Squamous Cell Carcinoma (TCGA): 3783.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 73.0;Esophageal cancer: 87.2;head and neck cancer: 225.0" NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 84: Apical squamous epithelium - Cornification" 4 "unprognostic (1.08e-1)" "unprognostic (3.25e-1)" "unprognostic (2.64e-1)" "unprognostic (3.22e-1)" "unprognostic (1.75e-1)" "unprognostic (3.27e-2)" "unprognostic (1.29e-2)" "potential prognostic unfavorable (1.52e-4)" "unprognostic (9.50e-3)" "unprognostic (3.09e-2)" "unprognostic (1.95e-1)" "unprognostic (2.01e-1)" "validated prognostic unfavorable (5.94e-5)" "validated prognostic unfavorable (2.11e-4)" "unprognostic (3.04e-1)" "unprognostic (3.85e-2)" "unprognostic (2.16e-1)" "unprognostic (1.20e-1)" "unprognostic (5.95e-2)" "unprognostic (2.31e-1)" "unprognostic (3.70e-1)" SPRR2A ENSG00000241794 "Small proline rich protein 2A" P35326 1 153056120-153057512 "Predicted intracellular proteins, Predicted secreted proteins" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 1417.8;esophagus: 5424.3;vagina: 1296.9" "Cell type enriched" "Detected in some" 6 "Esophageal apical cells: 42736.4" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "Head and Neck Squamous Cell Carcinoma (TCGA): 2187.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "head and neck cancer: 43.1" "Secreted to digestive system" Defense NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 6 "unprognostic (4.66e-2)" "unprognostic (4.25e-1)" "unprognostic (5.08e-2)" "unprognostic (3.90e-1)" "unprognostic (1.54e-2)" "unprognostic (2.75e-2)" "unprognostic (5.94e-3)" "unprognostic (1.48e-1)" "unprognostic (3.47e-2)" "unprognostic (1.72e-1)" "unprognostic (1.63e-3)" "unprognostic (4.87e-2)" "unprognostic (1.62e-2)" "unprognostic (2.83e-1)" "unprognostic (2.59e-2)" "unprognostic (4.77e-2)" SPRR2B ENSG00000196805 "Small proline rich protein 2B" P35325 1 153070226-153071611 "Predicted intracellular proteins" Keratinization "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "cervix: 44.1;esophagus: 51.2;skin 1: 41.3" "Cell type enriched" "Detected in some" 5 "Esophageal apical cells: 741.2" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Head and Neck Squamous Cell Carcinoma (TCGA): 186.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" "unprognostic (5.65e-2)" "unprognostic (1.73e-1)" "unprognostic (5.82e-3)" "unprognostic (1.15e-1)" "unprognostic (2.39e-1)" "unprognostic (3.59e-1)" SPRR2D ENSG00000163216 "Small proline rich protein 2D" P22532 1 153039732-153041931 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 746.0;esophagus: 1960.9;vagina: 486.9" "Cell type enriched" "Detected in some" 14 "Esophageal apical cells: 24737.1" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Head and Neck Squamous Cell Carcinoma (TCGA): 1248.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 68.1;skin cancer: 31.6" NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 2 "unprognostic (2.16e-2)" "unprognostic (1.02e-1)" "unprognostic (2.37e-1)" "unprognostic (1.21e-1)" "unprognostic (5.34e-2)" "unprognostic (3.42e-3)" "unprognostic (4.18e-3)" "unprognostic (2.38e-2)" "unprognostic (3.56e-1)" "validated prognostic unfavorable (7.74e-4)" "validated prognostic unfavorable (1.02e-4)" "unprognostic (4.63e-1)" "unprognostic (1.58e-1)" "unprognostic (1.15e-1)" "unprognostic (4.66e-2)" "unprognostic (5.45e-1)" SPRR2E ENSG00000203785 "Small proline rich protein 2E" P22531 1 153093135-153106184 "Predicted intracellular proteins" Keratinization "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "esophagus: 1664.7;skin 1: 1202.2" "Cell type enriched" "Detected in some" 7 "Esophageal apical cells: 26216.4" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "Head and Neck Squamous Cell Carcinoma (TCGA): 1481.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Esophageal cancer: 9.7;head and neck cancer: 23.7" NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 1 "unprognostic (4.44e-2)" "unprognostic (1.63e-1)" "unprognostic (1.39e-1)" "unprognostic (2.81e-2)" "unprognostic (1.46e-2)" "unprognostic (1.14e-1)" "unprognostic (3.36e-1)" "unprognostic (2.84e-1)" "unprognostic (1.30e-1)" "unprognostic (9.68e-2)" SPRR2F ENSG00000244094 "Small proline rich protein 2F" Q96RM1 1 153112121-153113516 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 4 "cervix: 92.6;esophagus: 253.6;lymphoid tissue: 65.8;ovary: 110.5" "Group enriched" "Detected in some" 4 "Esophageal apical cells: 2322.5;Granulosa cells: 1441.1" "Not detected" "Not detected" "Group enriched" "Detected in many" 9 "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 37.3;Head and Neck Squamous Cell Carcinoma (TCGA): 126.5;Lung Squamous Cell Carcinoma (TCGA): 31.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "head and neck cancer: 2.1;pancreatic cancer: 2.7" "Adipose visceral - Mesothelial cells" NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 72: Neuronal - Signal transduction" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" "unprognostic (2.94e-2)" "unprognostic (9.09e-2)" "unprognostic (3.80e-1)" "unprognostic (1.02e-2)" "unprognostic (3.77e-2)" "unprognostic (1.07e-2)" "unprognostic (3.10e-1)" "unprognostic (2.48e-1)" "unprognostic (1.41e-1)" "unprognostic (1.75e-3)" "unprognostic (2.60e-1)" "unprognostic (3.85e-1)" "unprognostic (2.99e-1)" "unprognostic (2.43e-1)" SPRR2G ENSG00000159516 "Small proline rich protein 2G" Q9BYE4 1 153149582-153150890 "Essential proteins, Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 35 "skin 1: 928.8" "Cell type enriched" "Detected in some" 4 "Suprabasal keratinocytes: 121.1" "Not detected" "Not detected" "Group enriched" "Detected in many" 13 "Head and Neck Squamous Cell Carcinoma (TCGA): 445.5;Skin Cutaneous Melanoma (TCGA): 255.4" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 8 "head and neck cancer: 10.9" NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" "unprognostic (4.15e-2)" "unprognostic (3.07e-1)" "unprognostic (1.91e-1)" "unprognostic (1.01e-1)" "unprognostic (3.08e-1)" "unprognostic (1.56e-1)" "unprognostic (3.05e-1)" SPRR3 ENSG00000163209 "Small proline rich protein 3" Q9UBC9 1 153001747-153003856 "Cancer-related genes, Predicted intracellular proteins" Keratinization "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 5402.3;esophagus: 18307.4;vagina: 6111.3" "Cell type enriched" "Detected in some" 11 "Esophageal apical cells: 490164.6" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 612.6;Head and Neck Squamous Cell Carcinoma (TCGA): 1439.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder cancer: 54.4;cervical cancer: 48.5" "Not detected" "Not detected" HPA044467 Enhanced NA NA 300000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 84: Apical squamous epithelium - Cornification" 6 "HPA044467: " "unprognostic (2.86e-1)" "unprognostic (2.46e-2)" "unprognostic (1.85e-1)" "unprognostic (5.07e-3)" "unprognostic (5.07e-1)" "unprognostic (9.52e-3)" "unprognostic (1.44e-2)" "unprognostic (3.28e-3)" "unprognostic (6.92e-2)" "unprognostic (5.38e-3)" "unprognostic (1.73e-1)" "potential prognostic unfavorable (2.32e-5)" "unprognostic (1.67e-2)" "unprognostic (2.03e-1)" "unprognostic (1.02e-1)" "unprognostic (1.97e-1)" "unprognostic (5.95e-2)" "unprognostic (1.64e-1)" SPRR4 ENSG00000184148 "Small proline rich protein 4" Q96PI1 1 152970648-152972574 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "skin 1: 135.5" "Cell type enriched" "Detected in some" 8 "Late spermatids: 119.6" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Head and Neck Squamous Cell Carcinoma (TCGA): 28.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "Esophageal cancer: 2.0;head and neck cancer: 1.7" "Skin - Sebaceous gland cells, Testis - Late spermatids" "Not detected" "Not detected" HPA055963 Enhanced Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 37: Skin - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" "Nucleoplasm, Cytosol" "Nuclear membrane" "HPA055963: " "unprognostic (2.25e-1)" "unprognostic (1.21e-2)" "unprognostic (1.11e-2)" "unprognostic (7.77e-3)" "unprognostic (1.97e-1)" "unprognostic (7.01e-2)" SPRR5 ENSG00000283227 "Small proline rich protein 5" A0A1B0GTR4 1 152947206-152949255 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 22 "skin 1: 111.4" "Cell type enriched" "Detected in some" 13 "Esophageal apical cells: 128.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Head and Neck Squamous Cell Carcinoma (TCGA): 16.0;Skin Cutaneous Melanoma (TCGA): 9.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "head and neck cancer: 2.2" "Skin - Keratinocyte (granular)" NA NA "Cluster 37: Skin - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 84: Apical squamous epithelium - Cornification" "unprognostic (1.36e-1)" "unprognostic (3.03e-2)" "unprognostic (2.99e-1)" "unprognostic (6.68e-2)" "unprognostic (4.31e-2)" SPRTN "C1orf124, DKFZP547N043, DVC1, Spartan" ENSG00000010072 "SprT-like N-terminal domain" Q9H040 1 231337104-231355023 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "Hydrolase, Metalloprotease, Protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epicardial cells: 104.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025073 Uncertain Supported Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 39: Testis - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 46 Nucleoplasm "HPA025073: " "unprognostic (1.53e-1)" "unprognostic (1.59e-1)" "unprognostic (4.88e-2)" "unprognostic (5.40e-2)" "unprognostic (1.60e-1)" "unprognostic (2.39e-2)" "unprognostic (3.59e-2)" "unprognostic (1.80e-1)" "unprognostic (4.78e-2)" "potential prognostic favorable (4.87e-4)" "unprognostic (2.59e-1)" "unprognostic (2.41e-1)" "unprognostic (2.48e-2)" "unprognostic (8.91e-2)" "unprognostic (3.14e-1)" "unprognostic (5.32e-2)" "unprognostic (3.72e-2)" "unprognostic (3.88e-2)" "potential prognostic unfavorable (2.85e-4)" "unprognostic (1.89e-1)" "unprognostic (4.44e-2)" "unprognostic (4.98e-1)" "unprognostic (1.22e-1)" "unprognostic (1.26e-1)" "unprognostic (2.02e-1)" "unprognostic (3.93e-1)" "unprognostic (9.94e-2)" "unprognostic (1.39e-2)" "unprognostic (3.57e-1)" SPRY1 hSPRY1 ENSG00000164056 "Sprouty RTK signaling antagonist 1" O43609 4 123396795-123403760 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 225.1" "Cell type enhanced" "Detected in many" "Fibroblasts: 174.4;Innate lymphoid cells: 234.5;Leydig cells: 474.8;Mesothelial cells: 240.2;Myosatellite cells: 327.9;Pituicytes/FSCs: 216.5;Vascular endothelial cells: 500.8" "Cell type enhanced" "Detected in many" "Bergmann glia: 111.0;pericyte: 65.7;vascular associated smooth muscle cell: 63.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 61.4" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Liver - Hepatic stellate cells, Lung - Fibroblasts_1, Pituitary gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013538, HPA051369, HPA070554" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 66 "Golgi apparatus, Cytosol" Nucleoplasm "CAB013538: , HPA051369: , HPA070554: " "unprognostic (2.60e-2)" "unprognostic (1.12e-1)" "unprognostic (2.40e-3)" "unprognostic (7.61e-2)" "unprognostic (3.11e-1)" "unprognostic (8.13e-3)" "unprognostic (7.09e-2)" "unprognostic (1.14e-2)" "unprognostic (5.72e-2)" "unprognostic (1.01e-2)" "validated prognostic favorable (6.25e-6)" "validated prognostic favorable (3.24e-5)" "unprognostic (1.17e-3)" "unprognostic (1.23e-1)" "unprognostic (1.53e-2)" "unprognostic (1.99e-2)" "unprognostic (1.77e-1)" "unprognostic (2.18e-2)" "unprognostic (1.68e-1)" "unprognostic (1.49e-1)" "unprognostic (1.48e-2)" "unprognostic (5.32e-1)" "unprognostic (1.70e-1)" "unprognostic (2.44e-2)" "unprognostic (2.73e-1)" "unprognostic (2.80e-3)" "unprognostic (3.80e-2)" "unprognostic (1.18e-2)" "unprognostic (1.09e-1)" "unprognostic (1.36e-2)" "unprognostic (3.59e-2)" SPRY2 hSPRY2 ENSG00000136158 "Sprouty RTK signaling antagonist 2" O43597 13 80335976-80341126 "Disease related genes, Plasma proteins, Predicted membrane proteins" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bergmann glia: 133.5;Epididymal basal cells: 103.0;Müller glia: 99.2;Schwann cells: 86.7" "Cell type enhanced" "Detected in all" "Bergmann glia: 157.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 4.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037205, HPA042198" Approved Supported "Actin filaments,Microtubules" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 25: Non-specific - Transcription" "Cluster 69: Skin cancer - ECM organization" "Cluster 110: Mural cells - ECM organization" 80 "Actin filaments, Microtubules" "CAB037205: , HPA042198: " "unprognostic (1.30e-1)" "unprognostic (2.27e-2)" "unprognostic (2.05e-1)" "unprognostic (6.16e-3)" "unprognostic (1.42e-1)" "unprognostic (6.04e-2)" "unprognostic (5.60e-2)" "unprognostic (9.44e-3)" "unprognostic (4.54e-2)" "unprognostic (1.75e-2)" "validated prognostic favorable (4.41e-5)" "validated prognostic favorable (3.37e-4)" "unprognostic (1.08e-2)" "unprognostic (8.86e-3)" "unprognostic (9.05e-3)" "unprognostic (6.39e-3)" "unprognostic (2.52e-3)" "unprognostic (1.12e-1)" "unprognostic (4.29e-2)" "unprognostic (1.47e-1)" "unprognostic (1.10e-1)" "unprognostic (1.42e-1)" "unprognostic (3.92e-1)" "unprognostic (9.84e-2)" "unprognostic (1.76e-1)" "unprognostic (2.26e-2)" "unprognostic (3.86e-2)" "unprognostic (2.29e-1)" "unprognostic (3.82e-1)" "unprognostic (1.05e-1)" "unprognostic (6.28e-3)" SPRY3 HSPRY3 ENSG00000168939 "Sprouty RTK signaling antagonist 3" O43610 X 155612572-155782459 "Predicted membrane proteins" Neurogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 743.2;Endometrial ciliated cells: 162.9;Endometrial luminal cells: 125.8;Myonuclei: 301.4;Neutrophil progenitors: 202.8;Neutrophils: 153.9" "Cell type enhanced" "Detected in all" "endothelial cell: 154.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" CAB013505 Uncertain Approved Nucleoli,Cytosol NA NA "Cluster 64: Non-specific - Transcription" "Cluster 35: Non-specific - DNA binding" "Cluster 7: Liver cancer - Metabolism" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 22 Cytosol Nucleoli "CAB013505: " "unprognostic (1.13e-2)" "unprognostic (2.09e-3)" "unprognostic (2.01e-1)" "unprognostic (9.37e-2)" "unprognostic (2.43e-1)" "unprognostic (4.07e-1)" "unprognostic (2.58e-2)" "unprognostic (1.59e-2)" "unprognostic (1.09e-1)" "unprognostic (1.66e-1)" SPRY4 ENSG00000187678 "Sprouty RTK signaling antagonist 4" Q9C004 5 142310427-142326455 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 37.8;Adrenal medulla cells: 74.5;Alveolar cells type 2: 98.0;Bergmann glia: 35.4;Oligodendrocyte progenitor cells: 99.5;Pericytes: 42.1;Pituicytes/FSCs: 65.4;Vascular endothelial cells: 36.5" "Cell type enhanced" "Detected in many" "fibroblast: 101.7;oligodendrocyte precursor cell: 97.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "skin cancer: 70.1" "Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008086, HPA055471, HPA072661" Enhanced Approved "Golgi apparatus,Cytosol" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 23: Choroid plexus - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 47 "Golgi apparatus" Cytosol "CAB008086: , HPA055471: , HPA072661: " "unprognostic (1.71e-2)" "unprognostic (6.90e-3)" "unprognostic (8.84e-2)" "unprognostic (3.46e-3)" "unprognostic (2.27e-1)" "unprognostic (2.82e-3)" "unprognostic (1.49e-1)" "potential prognostic unfavorable (5.80e-4)" "unprognostic (4.62e-2)" "unprognostic (2.43e-1)" "validated prognostic favorable (2.13e-5)" "validated prognostic favorable (1.31e-4)" "unprognostic (6.77e-3)" "unprognostic (2.77e-3)" "unprognostic (8.61e-3)" "unprognostic (2.14e-1)" "unprognostic (1.30e-2)" "unprognostic (4.12e-2)" "unprognostic (3.91e-1)" "unprognostic (6.89e-3)" "unprognostic (1.28e-1)" "unprognostic (1.10e-1)" "unprognostic (4.77e-2)" "unprognostic (6.85e-2)" "unprognostic (3.45e-1)" "unprognostic (1.07e-1)" "unprognostic (1.12e-1)" "unprognostic (2.73e-2)" "unprognostic (7.80e-2)" "unprognostic (9.70e-2)" "unprognostic (1.08e-1)" SPRYD3 FLJ14800 ENSG00000167778 "SPRY domain containing 3" Q8NCJ5 12 53064316-53079404 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039426, HPA039685" Enhanced Approved "Nucleoplasm,Vesicles,Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 73: Brain - Neuronal signaling" "Cluster 24: Neurons - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 62: Smooth muscle cells - Muscle contraction" 12 "Nucleoplasm, Cytosol" "Vesicles, Plasma membrane, Actin filaments" "HPA039426: , HPA039685: " "unprognostic (9.26e-2)" "unprognostic (1.72e-2)" "unprognostic (2.81e-2)" "unprognostic (1.63e-2)" "unprognostic (1.64e-1)" "unprognostic (1.54e-2)" "unprognostic (8.53e-2)" "unprognostic (3.03e-1)" "unprognostic (7.88e-3)" "unprognostic (1.85e-1)" "potential prognostic favorable (7.71e-9)" "unprognostic (1.72e-3)" "potential prognostic favorable (5.40e-4)" "potential prognostic unfavorable (2.45e-4)" "unprognostic (1.02e-3)" "unprognostic (1.66e-1)" "unprognostic (1.21e-1)" "unprognostic (1.11e-1)" "unprognostic (4.45e-2)" "unprognostic (4.53e-2)" "unprognostic (1.36e-2)" "unprognostic (1.11e-2)" "unprognostic (3.18e-1)" "unprognostic (1.05e-1)" "unprognostic (2.19e-2)" "unprognostic (1.10e-1)" "unprognostic (1.47e-1)" "unprognostic (1.93e-1)" "unprognostic (7.08e-2)" "unprognostic (9.69e-2)" "unprognostic (2.23e-1)" SPRYD4 DKFZp686N0877 ENSG00000176422 "SPRY domain containing 4" Q8WW59 12 56468578-56479708 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 19.3" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 63.5;Esophageal suprabasal cells: 68.7;Hepatocytes: 149.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053469 Uncertain Approved Nucleoplasm NA NA 75000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 53: Liver - Plasma proteins" "Cluster 15: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 10 Nucleoplasm "HPA053469: " "unprognostic (6.82e-2)" "unprognostic (1.21e-1)" "unprognostic (1.48e-2)" "unprognostic (4.76e-2)" "unprognostic (5.80e-2)" "unprognostic (2.90e-2)" "unprognostic (5.49e-3)" "potential prognostic favorable (1.34e-4)" "unprognostic (1.08e-1)" "unprognostic (6.34e-2)" "unprognostic (5.41e-3)" "unprognostic (3.80e-2)" "potential prognostic favorable (1.86e-4)" "unprognostic (3.27e-3)" "unprognostic (7.75e-2)" "unprognostic (2.29e-2)" "unprognostic (1.83e-1)" "potential prognostic favorable (3.96e-4)" "unprognostic (6.46e-3)" "unprognostic (5.90e-2)" "unprognostic (9.54e-2)" "unprognostic (1.21e-2)" "unprognostic (2.92e-1)" "unprognostic (1.39e-1)" "unprognostic (7.51e-2)" "unprognostic (8.43e-2)" "unprognostic (5.08e-3)" "unprognostic (1.90e-2)" "unprognostic (2.26e-1)" "unprognostic (2.37e-1)" "unprognostic (1.92e-1)" SPRYD7 "C13orf1, CLLD6" ENSG00000123178 "SPRY domain containing 7" Q5W111 13 49912702-49936490 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 177.5;Early primary spermatocytes: 105.1;Early spermatids: 106.1;Late primary spermatocytes: 283.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043934 Approved Approved Vesicles NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 19: Non-specific - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 15 Vesicles "HPA043934: " "unprognostic (1.06e-1)" "unprognostic (2.06e-2)" "unprognostic (1.33e-3)" "unprognostic (1.71e-1)" "unprognostic (2.58e-1)" "unprognostic (1.88e-1)" "unprognostic (8.14e-2)" "unprognostic (1.23e-3)" "unprognostic (6.42e-2)" "potential prognostic favorable (3.54e-7)" "unprognostic (9.98e-3)" "unprognostic (2.60e-3)" "unprognostic (1.30e-1)" "unprognostic (7.76e-2)" "unprognostic (8.81e-2)" "unprognostic (2.74e-1)" "unprognostic (5.28e-2)" "unprognostic (6.16e-2)" "unprognostic (9.48e-3)" "unprognostic (4.23e-3)" "unprognostic (4.36e-2)" "unprognostic (4.51e-2)" "unprognostic (6.10e-2)" "unprognostic (9.03e-2)" "unprognostic (2.16e-1)" "unprognostic (1.30e-1)" "unprognostic (3.60e-2)" "unprognostic (1.41e-1)" "unprognostic (2.43e-2)" "unprognostic (1.33e-1)" SPSB1 SSB-1 ENSG00000171621 "SplA/ryanodine receptor domain and SOCS box containing 1" Q96BD6 1 9292894-9369532 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 422.8;Endometrial luminal cells: 234.3;Endometrial secretory cells: 219.4;Epididymal basal cells: 427.1;Podocytes: 220.4;Salivary myoepithelial cells: 252.0" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 84.8;fibroblast: 42.4;oligodendrocyte: 48.2;oligodendrocyte precursor cell: 43.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.2" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 11: White matter - Signal transduction" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 103: Non-specific - Basic cellular processes" 32 "unprognostic (1.61e-1)" "unprognostic (6.12e-2)" "unprognostic (4.36e-1)" "unprognostic (1.05e-1)" "unprognostic (1.10e-1)" "unprognostic (2.85e-2)" "unprognostic (2.80e-2)" "unprognostic (2.44e-1)" "unprognostic (1.32e-1)" "unprognostic (3.03e-2)" "unprognostic (1.11e-1)" "unprognostic (1.92e-1)" "unprognostic (1.95e-1)" "unprognostic (9.24e-2)" "unprognostic (5.25e-2)" "unprognostic (1.23e-1)" "potential prognostic unfavorable (1.98e-4)" "unprognostic (5.85e-2)" "unprognostic (2.82e-2)" "potential prognostic unfavorable (4.68e-4)" "unprognostic (1.71e-2)" "unprognostic (3.35e-2)" "unprognostic (2.33e-1)" "unprognostic (2.64e-1)" "unprognostic (1.68e-1)" "unprognostic (4.32e-3)" "unprognostic (3.89e-2)" "unprognostic (1.71e-2)" "unprognostic (3.78e-2)" "unprognostic (2.56e-3)" "unprognostic (8.28e-2)" SPSB2 "GRCC9, SSB-2" ENSG00000111671 "SplA/ryanodine receptor domain and SOCS box containing 2" Q99619 12 6870935-6889358 "Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 42.2;Epicardial cells: 109.2;Late primary spermatocytes: 47.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 114.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055225 Approved NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 72: Kidney - Transmembrane transport" "Cluster 25: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 65: Non-specific - Cell growth & division" 51 "HPA055225: " "potential prognostic unfavorable (8.40e-4)" "unprognostic (1.26e-1)" "unprognostic (1.24e-1)" "unprognostic (2.02e-1)" "unprognostic (4.02e-2)" "unprognostic (8.92e-2)" "unprognostic (2.77e-2)" "unprognostic (2.79e-2)" "unprognostic (7.70e-2)" "unprognostic (3.74e-1)" "unprognostic (1.91e-3)" "unprognostic (2.32e-3)" "unprognostic (5.62e-2)" "potential prognostic unfavorable (1.44e-5)" "unprognostic (1.89e-2)" "unprognostic (3.75e-1)" "unprognostic (2.03e-1)" "unprognostic (1.84e-1)" "unprognostic (3.04e-1)" "unprognostic (3.20e-2)" "unprognostic (4.64e-2)" "unprognostic (1.74e-1)" "unprognostic (1.18e-1)" "unprognostic (1.07e-1)" "unprognostic (1.23e-2)" "unprognostic (4.61e-2)" "unprognostic (2.00e-1)" "unprognostic (1.97e-2)" "unprognostic (2.98e-1)" "unprognostic (3.10e-1)" "unprognostic (2.53e-1)" SPSB3 "C16orf31, SSB-3" ENSG00000162032 "SplA/ryanodine receptor domain and SOCS box containing 3" Q6PJ21 16 1776712-1793700 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 618.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046602 Uncertain Approved Mitochondria NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 24: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 54: Non-specific - Transcription" "Cluster 84: Apical squamous epithelium - Cornification" 9 Mitochondria "HPA046602: " "unprognostic (1.83e-1)" "unprognostic (1.98e-1)" "unprognostic (1.53e-1)" "unprognostic (1.17e-2)" "unprognostic (1.51e-1)" "unprognostic (3.79e-1)" "unprognostic (6.26e-2)" "unprognostic (1.63e-3)" "unprognostic (2.38e-2)" "unprognostic (3.46e-2)" "potential prognostic favorable (5.92e-10)" "unprognostic (8.29e-3)" "potential prognostic favorable (1.54e-4)" "unprognostic (5.47e-2)" "unprognostic (2.02e-2)" "unprognostic (9.26e-2)" "unprognostic (1.47e-1)" "unprognostic (7.38e-2)" "unprognostic (3.10e-1)" "unprognostic (9.87e-3)" "unprognostic (9.32e-2)" "unprognostic (2.80e-1)" "unprognostic (1.50e-1)" "unprognostic (2.87e-1)" "potential prognostic favorable (7.31e-4)" "unprognostic (3.15e-1)" "unprognostic (9.98e-2)" "unprognostic (1.55e-1)" "unprognostic (9.68e-2)" "unprognostic (2.86e-2)" "unprognostic (1.91e-1)" SPSB4 SSB-4 ENSG00000175093 "SplA/ryanodine receptor domain and SOCS box containing 4" Q96A44 3 141051347-141148611 "Predicted intracellular proteins" "Biological rhythms, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "pancreas: 11.9;testis: 6.9" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 82.7;Early spermatids: 47.7;Fibro-adipogenic progenitors: 47.6;Gonadotrophs: 50.5;Kupffer cells: 59.4;Lactotrophs: 74.8;Late primary spermatocytes: 49.0;Late spermatids: 23.7;Megakaryocytes: 55.6;Oligodendrocyte progenitor cells: 76.0;Pancreatic acinar cells: 38.9;Renal collecting duct intercalated cells: 33.8;Somatotrophs: 29.9;Thyrotrophs: 40.6" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 66.7;oligodendrocyte precursor cell: 96.5" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 4.8;Kidney Chromophobe (TCGA): 3.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 13.4;testis cancer: 45.8" "Adrenal gland - Adrenal medulla cells, Heart muscle - Cardiomyocytes, Liver - Kupffer cells, Minor Salivary Gland - Fibroblasts, Prostate - Fibroblasts, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Spleen - Macrophages, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA062793 Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 43: Hindbrain - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 43 "Nucleoplasm, Golgi apparatus" "HPA062793: " "unprognostic (9.59e-2)" "unprognostic (1.20e-2)" "unprognostic (2.00e-3)" "unprognostic (1.23e-1)" "unprognostic (1.54e-1)" SPTA1 EL2 ENSG00000163554 "Spectrin alpha, erythrocytic 1" P02549 1 158610704-158686715 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell shape" "Actin capping, Actin-binding" "Disease variant, Elliptocytosis, Hereditary hemolytic anemia, Pyropoikilocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 45 "bone marrow: 71.4" "Cell type enriched" "Detected in some" 4 "Erythrocyte progenitors: 538.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 18 "Leukemia: 10.3" "Liver - Erythroid cells, Lung - Neutrophils_1, Spleen - Erythrocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "CAB016193, HPA028048, HPA028253, CAB037246" Enhanced NA NA 42000000 "Cluster 15: Bone marrow - Innate immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 21 "CAB016193: , CAB037246: , HPA028048: , HPA028253: " SPTAN1 ENSG00000197694 "Spectrin alpha, non-erythrocytic 1" Q13813 9 128552558-128633662 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin capping, Actin-binding, Calmodulin-binding" "Disease variant, Epilepsy, Hereditary spastic paraplegia, Intellectual disability, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Retinal ganglion cells: 567.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004581, HPA007927" Enhanced Approved Vesicles,Microtubules NA NA 1600000 "Cluster 16: Non-specific - Cell proliferation" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 24: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 20: Non-specific - Transcription regulation" 89 "Vesicles, Microtubules" "CAB004581: , HPA007927: " "unprognostic (7.13e-2)" "unprognostic (1.48e-1)" "unprognostic (7.67e-2)" "unprognostic (2.82e-3)" "unprognostic (1.33e-1)" "unprognostic (6.69e-2)" "unprognostic (4.29e-2)" "unprognostic (1.03e-1)" "unprognostic (9.86e-2)" "unprognostic (7.99e-2)" "validated prognostic favorable (4.05e-9)" "validated prognostic favorable (1.32e-4)" "unprognostic (1.15e-1)" "unprognostic (3.53e-2)" "unprognostic (7.17e-2)" "unprognostic (1.05e-1)" "unprognostic (1.73e-2)" "unprognostic (4.21e-3)" "unprognostic (4.04e-2)" "unprognostic (7.91e-3)" "unprognostic (4.41e-1)" "unprognostic (2.07e-1)" "unprognostic (1.19e-1)" "unprognostic (2.35e-1)" "unprognostic (5.18e-2)" "potential prognostic favorable (2.68e-4)" "unprognostic (1.44e-1)" "unprognostic (5.75e-2)" "unprognostic (1.89e-1)" "unprognostic (3.46e-2)" "unprognostic (3.07e-1)" SPTB ENSG00000070182 "Spectrin beta, erythrocytic" P11277 14 64746283-64879907 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Disease variant, Elliptocytosis, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 59.0;skeletal muscle: 153.7;tongue: 65.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 127.8;Choroid plexus epithelial cells: 185.4;Epicardial cells: 79.6;Erythrocyte progenitors: 296.7;Myonuclei: 310.1;Platelets: 79.1;Podocytes: 113.6;Thymic myoid cells: 310.0;Thyrotrophs: 108.6" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 7.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Leukemia: 7.7;lung cancer: 7.9" "Adrenal gland - Adrenal medulla cells, Kidney - Podocytes, Liver - Erythroid cells, Spleen - Erythrocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003394, HPA003398, CAB015169, CAB016232" Enhanced Approved Cytosol NA NA 35000000 "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 37: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 9 Cytosol "CAB015169: , CAB016232: , HPA003394: , HPA003398: " "unprognostic (7.67e-2)" "unprognostic (1.48e-1)" "unprognostic (2.35e-1)" "unprognostic (5.05e-3)" "unprognostic (4.97e-2)" "unprognostic (4.56e-3)" "unprognostic (1.91e-1)" "unprognostic (6.56e-2)" "potential prognostic favorable (7.35e-4)" "unprognostic (1.06e-3)" "unprognostic (1.64e-1)" "unprognostic (2.13e-1)" "unprognostic (7.34e-3)" SPTBN1 ENSG00000115306 "Spectrin beta, non-erythrocytic 1" Q01082 2 54456317-54671446 "Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Actin capping, Actin-binding, Calmodulin-binding" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 1149.7;Fibro-adipogenic progenitors: 913.3;Leydig cells: 934.1;Lymphatic endothelial cells: 919.1;Vascular endothelial cells: 928.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012685, HPA013149" Supported Uncertain Cytosol NA Yes 1800000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 52 Cytosol "HPA012685: , HPA013149: " "unprognostic (1.01e-1)" "unprognostic (4.50e-1)" "unprognostic (8.13e-3)" "potential prognostic unfavorable (8.20e-4)" "unprognostic (3.40e-2)" "unprognostic (1.55e-1)" "unprognostic (3.19e-2)" "unprognostic (1.34e-2)" "unprognostic (5.17e-2)" "unprognostic (1.66e-2)" "validated prognostic favorable (7.27e-10)" "validated prognostic favorable (1.39e-5)" "unprognostic (6.95e-2)" "unprognostic (2.65e-1)" "unprognostic (2.43e-1)" "unprognostic (2.83e-2)" "unprognostic (1.98e-1)" "unprognostic (3.06e-2)" "unprognostic (4.63e-1)" "unprognostic (5.58e-2)" "unprognostic (1.84e-1)" "unprognostic (6.68e-3)" "unprognostic (2.81e-1)" "unprognostic (9.58e-2)" "unprognostic (1.99e-2)" "unprognostic (2.06e-2)" "unprognostic (5.35e-2)" "unprognostic (3.12e-1)" "unprognostic (3.77e-1)" "unprognostic (6.28e-3)" "unprognostic (3.15e-1)" SPTBN2 SCA5 ENSG00000173898 "Spectrin beta, non-erythrocytic 2" O15020 11 66682497-66744670 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 58.7;skin 1: 59.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 209.1;Esophageal apical cells: 110.5;Late spermatids: 136.4;Ocular epithelial cells: 152.9;Renal collecting duct intercalated cells: 139.3;Renal collecting duct principal cells: 105.8;Retinal pigment epithelial cells: 149.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Prostate glandular cells, Stomach - Chief cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009844, HPA039293, HPA043529" Enhanced Supported "Vesicles,Plasma membrane,Cytosol" NA NA 410000 "Cluster 2: Non-specific - Mixed function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" 20 "Plasma membrane, Cytosol" Vesicles "CAB009844: , HPA039293: , HPA043529: " "unprognostic (1.95e-1)" "unprognostic (7.06e-2)" "unprognostic (3.95e-3)" "unprognostic (2.65e-1)" "unprognostic (1.55e-1)" "unprognostic (1.15e-2)" "unprognostic (3.65e-1)" "potential prognostic favorable (3.77e-5)" "unprognostic (1.16e-2)" "unprognostic (5.50e-2)" "validated prognostic unfavorable (4.53e-6)" "validated prognostic unfavorable (9.00e-4)" "unprognostic (1.92e-1)" "unprognostic (3.53e-2)" "potential prognostic favorable (1.34e-4)" "unprognostic (1.97e-3)" "potential prognostic unfavorable (7.79e-4)" "unprognostic (2.74e-1)" "unprognostic (6.04e-3)" "unprognostic (5.86e-2)" "unprognostic (3.20e-1)" "potential prognostic unfavorable (3.58e-5)" "unprognostic (3.77e-3)" "unprognostic (2.95e-1)" "unprognostic (2.48e-2)" "unprognostic (3.37e-1)" "unprognostic (4.22e-2)" "unprognostic (1.14e-1)" "unprognostic (5.37e-2)" "unprognostic (1.07e-1)" "unprognostic (1.12e-1)" SPTBN4 "KIAA1642, SPTBN3" ENSG00000160460 "Spectrin beta, non-erythrocytic 4" Q9H254 19 40466241-40576464 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Deafness, Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 24.8;pituitary gland: 7.4" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 148.9;Brain excitatory neurons: 308.1;Brain inhibitory neurons: 284.7;Gonadotrophs: 142.1;Other brain neurons: 181.6;Retinal amacrine cells: 402.1;Retinal bipolar cells: 231.4;Retinal ganglion cells: 536.9;Retinal horizontal cells: 316.5;Rod photoreceptor cells: 173.1;Somatotrophs: 127.0;Thyrotrophs: 154.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Kidney Chromophobe (TCGA): 7.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 4.8" "Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Pancreas - Alpha cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054481 Enhanced Approved Nucleoplasm,Nucleoli NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 7 Nucleoli Nucleoplasm "HPA054481: " "unprognostic (2.88e-3)" "unprognostic (9.52e-2)" "unprognostic (6.81e-2)" "unprognostic (2.74e-1)" "unprognostic (3.29e-1)" "unprognostic (1.91e-2)" "unprognostic (1.20e-3)" "unprognostic (5.34e-2)" "unprognostic (1.60e-1)" "unprognostic (9.60e-2)" SPTBN5 "BSPECV, HUBSPECV, HUSPECV" ENSG00000137877 "Spectrin beta, non-erythrocytic 5" Q9NRC6 15 41848146-41894053 "Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 7.1;retina: 25.0" "Cell type enriched" "Detected in many" 5 "Cardiomyocytes: 773.4" "Cell type enhanced" "Detected in many" "upper rhombic lip: 11.5" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in all" 5 "cerebellum: 19.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "spinal cord: 4.6" HPA055283 Enhanced NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 35: Non-specific - DNA binding" "Cluster 32: Non-specific - Cell proliferation" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 1 "HPA055283: " "unprognostic (9.31e-2)" "unprognostic (9.43e-2)" "unprognostic (2.23e-2)" "unprognostic (1.97e-1)" "unprognostic (6.30e-2)" "unprognostic (2.37e-1)" "unprognostic (7.57e-2)" "unprognostic (1.28e-3)" "unprognostic (1.28e-1)" "unprognostic (3.17e-2)" "unprognostic (1.51e-2)" "unprognostic (1.53e-2)" SPTLC1 "hLCB1, HSAN1, HSN1, LCB1, SPTI" ENSG00000090054 "Serine palmitoyltransferase long chain base subunit 1" O15269 9 92000087-92115413 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Acyltransferase, Transferase" "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 738.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010860, CAB018747, HPA063907" Supported Supported "Endoplasmic reticulum" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 84: Apical squamous epithelium - Cornification" 38 "Endoplasmic reticulum" "CAB018747: , HPA010860: , HPA063907: " "unprognostic (1.78e-1)" "unprognostic (8.01e-2)" "unprognostic (1.46e-2)" "unprognostic (1.31e-2)" "unprognostic (1.72e-1)" "unprognostic (3.11e-1)" "unprognostic (7.35e-2)" "unprognostic (5.59e-2)" "unprognostic (2.74e-3)" "unprognostic (4.16e-1)" "potential prognostic favorable (9.74e-7)" "unprognostic (8.06e-3)" "unprognostic (4.70e-3)" "unprognostic (9.01e-3)" "unprognostic (5.06e-2)" "unprognostic (2.11e-3)" "unprognostic (5.37e-2)" "unprognostic (7.09e-2)" "unprognostic (3.16e-1)" "unprognostic (9.35e-2)" "unprognostic (6.61e-3)" "unprognostic (2.29e-3)" "unprognostic (7.63e-2)" "unprognostic (5.46e-2)" "unprognostic (1.14e-2)" "unprognostic (2.36e-1)" "unprognostic (1.15e-1)" "unprognostic (5.99e-2)" "unprognostic (5.21e-2)" "unprognostic (3.37e-1)" "unprognostic (2.29e-1)" SPTLC2 "hLCB2a, KIAA0526, LCB2, LCB2A" ENSG00000100596 "Serine palmitoyltransferase long chain base subunit 2" O15270 14 77505997-77616637 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Acyltransferase, Transferase" "Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 493.8;Monocyte progenitors: 566.0;Neutrophil progenitors: 656.0;Neutrophils: 1178.6;Tuft cells: 830.0" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 324.7;oligodendrocyte: 302.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075143 Approved "Plasma membrane,Cell Junctions" NA No "Cluster 10: Non-specific - Membrane trafficking" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 20 "Plasma membrane" "Cell Junctions" "HPA075143: " "unprognostic (9.59e-2)" "unprognostic (1.83e-1)" "unprognostic (9.13e-2)" "unprognostic (1.02e-1)" "unprognostic (5.12e-2)" "unprognostic (3.38e-1)" "unprognostic (2.95e-1)" "unprognostic (1.50e-1)" "unprognostic (3.76e-1)" "unprognostic (6.80e-3)" "validated prognostic favorable (4.42e-6)" "validated prognostic favorable (3.75e-4)" "unprognostic (8.45e-2)" "unprognostic (2.25e-3)" "unprognostic (1.02e-2)" "unprognostic (1.18e-1)" "unprognostic (1.85e-1)" "unprognostic (2.46e-2)" "unprognostic (6.24e-2)" "unprognostic (8.25e-2)" "unprognostic (1.49e-3)" "unprognostic (9.11e-3)" "unprognostic (3.84e-3)" "unprognostic (2.87e-1)" "unprognostic (4.32e-2)" "unprognostic (1.86e-1)" "unprognostic (2.96e-1)" "unprognostic (4.10e-2)" "unprognostic (2.50e-1)" "unprognostic (3.55e-1)" "unprognostic (4.66e-1)" SPTLC3 "C20orf38, FLJ11112, hLCB2b, LCB2B, SPTLC2L" ENSG00000172296 "Serine palmitoyltransferase long chain base subunit 3" Q9NUV7 20 13008972-13169103 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 284.3;Endometrial luminal cells: 127.2;Pituicytes/FSCs: 183.0;Proximal tubule cells: 128.3;Renal collecting duct intercalated cells: 180.2;Salivary ionocytes: 133.9;Sertoli cells: 154.2;Syncytiotrophoblasts: 126.5;Thymocytes: 127.0" "Group enriched" "Detected in many" 4 "central nervous system macrophage: 139.0;choroid plexus epithelial cell: 45.9;endothelial cell: 40.7;fibroblast: 136.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 1.5" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA044247, HPA048079" Enhanced Approved Microtubules NA NA "Cluster 24: Non-specific - Transcription" "Cluster 58: Skin - Keratinization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 72: Neuronal - Signal transduction" "Cluster 51: Secretory epithelial cells - Mixed function" 3 Microtubules "HPA044247: , HPA048079: " "unprognostic (5.96e-2)" "unprognostic (1.65e-1)" "unprognostic (2.06e-1)" "unprognostic (3.57e-2)" "unprognostic (1.22e-1)" "unprognostic (5.59e-3)" "unprognostic (5.33e-2)" "unprognostic (4.44e-2)" "unprognostic (2.01e-1)" "unprognostic (1.23e-1)" "validated prognostic favorable (3.51e-7)" "validated prognostic favorable (1.86e-4)" "unprognostic (1.10e-2)" "unprognostic (4.09e-3)" "unprognostic (2.48e-2)" "unprognostic (2.57e-1)" "unprognostic (1.86e-1)" "unprognostic (1.23e-2)" "unprognostic (5.00e-2)" "unprognostic (6.03e-2)" "unprognostic (2.36e-1)" "potential prognostic unfavorable (1.28e-4)" "unprognostic (2.44e-1)" "unprognostic (5.85e-2)" "unprognostic (8.13e-2)" "unprognostic (1.14e-1)" "unprognostic (2.70e-1)" "unprognostic (5.44e-2)" "unprognostic (1.92e-1)" "unprognostic (4.11e-1)" "unprognostic (1.65e-1)" SPTSSA "C14orf147, ssSPTa" ENSG00000165389 "Serine palmitoyltransferase small subunit A" Q969W0 14 34432788-34462240 "Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Breast lactating cells: 7.5;Tuft cells: 11.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 76: Non-specific - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 4: Breast lactating luminal cells - Lactation" 6 "unprognostic (9.98e-2)" "unprognostic (1.04e-1)" "unprognostic (8.69e-2)" "unprognostic (1.30e-1)" "unprognostic (1.93e-2)" "unprognostic (6.14e-2)" "unprognostic (1.20e-1)" "unprognostic (4.71e-3)" "unprognostic (4.90e-3)" "unprognostic (3.76e-3)" "unprognostic (1.36e-1)" "unprognostic (1.70e-1)" "unprognostic (1.38e-1)" "unprognostic (7.87e-2)" "unprognostic (5.06e-2)" "unprognostic (1.04e-1)" "unprognostic (7.25e-2)" "unprognostic (3.04e-1)" "unprognostic (7.98e-2)" "unprognostic (6.84e-3)" "unprognostic (3.60e-3)" "unprognostic (3.56e-2)" "unprognostic (3.74e-1)" "unprognostic (1.47e-1)" "unprognostic (9.06e-2)" "unprognostic (4.53e-2)" "unprognostic (2.10e-1)" "unprognostic (9.25e-2)" "unprognostic (1.78e-1)" SPTSSB "ADMP, C3orf57, ssSPTb" ENSG00000196542 "Serine palmitoyltransferase small subunit B" Q8NFR3 3 161344798-161372880 "Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 58.9;stomach 1: 67.0;urinary bladder: 62.6" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 176.2;Foveolar cells: 215.3;Papillary tip epithelial cells: 48.0;Prostatic club cells: 129.8;Prostatic glandular cells: 213.1;Prostatic hillock cells: 64.4;Salivary duct cells: 76.4;Urothelial cells: 305.0" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 50.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 13 "NK-cell: 329.8" "Lineage enriched" "Detected in many" 13 "NK-cells: 329.8" "Group enriched" "Detected in many" 4 "breast cancer: 142.2;Gallbladder cancer: 77.8" "Minor Salivary Gland - Minor salivary gland ductal cells, Pancreas - Alpha cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 58: Skin - Keratinization" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 69: Urothelial cells - Basic cellular functions" 1 "unprognostic (2.83e-3)" "unprognostic (1.04e-1)" "unprognostic (1.51e-1)" "unprognostic (2.45e-1)" "unprognostic (1.70e-1)" "unprognostic (4.82e-2)" "unprognostic (6.79e-2)" "unprognostic (5.15e-2)" "unprognostic (6.17e-1)" "unprognostic (2.96e-2)" "unprognostic (4.61e-2)" "unprognostic (1.25e-1)" "unprognostic (1.16e-2)" "unprognostic (1.55e-1)" "unprognostic (2.29e-2)" "unprognostic (3.03e-1)" "unprognostic (3.87e-1)" "unprognostic (7.89e-2)" "unprognostic (4.83e-3)" "unprognostic (2.80e-1)" "unprognostic (1.31e-3)" "unprognostic (2.26e-1)" "unprognostic (5.86e-2)" "unprognostic (5.16e-2)" "unprognostic (4.57e-2)" SPTY2D1 "DKFZp686I068, FLJ39441, Spt2" ENSG00000179119 "SPT2 chromatin protein domain containing 1" Q68D10 11 18606403-18634791 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 32.3" "Cell type enhanced" "Detected in many" "Neutrophils: 207.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039372, HPA040177, HPA047957" Approved Enhanced Nucleoplasm,Nucleoli NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 15: Bone marrow - Innate immune response" "Cluster 31: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 4 "Nucleoplasm, Nucleoli" "HPA039372: , HPA040177: , HPA047957: " "unprognostic (4.90e-1)" "unprognostic (1.65e-1)" "unprognostic (1.28e-1)" "unprognostic (9.29e-3)" "unprognostic (3.95e-1)" "unprognostic (7.96e-2)" "unprognostic (1.15e-1)" "unprognostic (2.82e-1)" "unprognostic (1.08e-1)" "unprognostic (6.97e-3)" "validated prognostic favorable (1.18e-6)" "validated prognostic favorable (3.09e-4)" "unprognostic (2.45e-1)" "unprognostic (1.07e-2)" "unprognostic (9.51e-2)" "unprognostic (4.55e-2)" "unprognostic (1.27e-3)" "unprognostic (1.40e-2)" "unprognostic (2.26e-1)" "unprognostic (3.38e-1)" "potential prognostic unfavorable (3.04e-5)" "potential prognostic unfavorable (7.23e-4)" "unprognostic (2.12e-3)" "unprognostic (1.00e-1)" "potential prognostic favorable (3.08e-4)" "unprognostic (3.60e-1)" "unprognostic (1.91e-1)" "unprognostic (2.74e-1)" "unprognostic (2.95e-1)" "unprognostic (6.03e-2)" "unprognostic (1.64e-1)" SPTY2D1OS "Kastor, Polluks, SPTY2D1-AS1" ENSG00000247595 "SPTY2D1 opposite strand" A0A0U1RRN3 11 18588781-18610255 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in many" 35 "testis: 476.4" "Cell type enriched" "Detected in many" 5 "Late spermatids: 24676.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Testis - Late spermatids" "Intracellular and membrane" "No annotated function" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 6: Non-specific - Immune response" "Cluster 56: Non-specific - Sensory perception" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" "unprognostic (7.50e-2)" "unprognostic (3.03e-2)" "unprognostic (2.69e-1)" "unprognostic (2.08e-1)" "unprognostic (3.22e-2)" "unprognostic (1.06e-1)" "potential prognostic unfavorable (1.50e-4)" "unprognostic (2.52e-1)" "unprognostic (1.04e-1)" "unprognostic (1.56e-1)" "unprognostic (4.46e-2)" "unprognostic (3.17e-2)" "unprognostic (2.55e-1)" "unprognostic (2.57e-2)" "unprognostic (4.09e-2)" "unprognostic (3.87e-2)" "unprognostic (3.92e-2)" "unprognostic (7.52e-3)" "unprognostic (5.12e-2)" "unprognostic (1.12e-1)" "unprognostic (6.66e-2)" "unprognostic (5.62e-1)" "unprognostic (1.23e-1)" "unprognostic (9.15e-3)" SPX "C12orf39, MGC10946, NPQ, spexin" ENSG00000134548 "Spexin hormone" Q9BT56 12 21526296-21541249 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 104.7;pancreas: 38.8" "Cell type enhanced" "Detected in some" "Epididymal clear cells: 147.0;Epididymal efferent duct absorptive cells: 93.1;Epididymal efferent duct ciliated cells: 33.6;Megakaryocytes: 531.6;Platelets: 111.1" "Cell type enhanced" "Detected in many" "astrocyte: 30.1;Bergmann glia: 26.4" "Group enriched" "Detected in many" 7 "Kidney Chromophobe (TCGA): 58.8;Kidney Renal Clear Cell Carcinoma (TCGA): 22.3;Kidney Renal Papillary Cell Carcinoma (TCGA): 37.6" "Region enhanced" "Detected in all" "pons: 42.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 13.1;testis cancer: 13.4" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Lung - Fibroblasts_1, Skin - Adipocytes (Skin), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "cerebral cortex: 22.1;hippocampal formation: 22.7;olfactory bulb: 10.3;pons: 10.7" "Secreted to blood" Hormone NA NA 2650000 9400 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 7: Liver cancer - Metabolism" "Cluster 47: Platelets - Hemostasis" 1 "unprognostic (6.45e-2)" "unprognostic (1.11e-1)" "unprognostic (6.96e-2)" "validated prognostic favorable (5.81e-5)" "validated prognostic favorable (4.03e-5)" "potential prognostic unfavorable (5.98e-5)" "unprognostic (4.26e-1)" "unprognostic (1.43e-3)" "unprognostic (4.86e-2)" "unprognostic (4.67e-1)" "potential prognostic unfavorable (8.98e-4)" "unprognostic (7.75e-2)" "unprognostic (1.55e-2)" "unprognostic (8.41e-2)" SPZ1 "FLJ25709, NYD-TSP1, PPP1R148" ENSG00000164299 "Spermatogenic leucine zipper 1" Q9BXG8 5 80319625-80321842 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 267 "testis: 26.6" "Group enriched" "Detected in some" 8 "Early spermatids: 347.3;Late spermatids: 1348.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 14 "Prostate Adenocarcinoma (TCGA): 1.1;Testicular Germ Cell Tumor (TCGA): 1.6" "Region enriched" "Detected in single" 16 "choroid plexus: 8.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA037798 Approved "Mid piece" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 36: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 5 "Mid piece" "HPA037798: " "unprognostic (6.64e-2)" "unprognostic (3.23e-1)" SQLE ENSG00000104549 "Squalene epoxidase" Q14534 8 124998497-125022283 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 378.9;Esophageal suprabasal cells: 353.3;Suprabasal keratinocytes: 216.4;Syncytiotrophoblasts: 354.0;Urothelial cells: 295.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary gland basal cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018038, HPA020762" Enhanced Uncertain Vesicles,Cytosol NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 43: Hindbrain - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 69: Urothelial cells - Basic cellular functions" 8 "Vesicles, Cytosol" "HPA018038: , HPA020762: " "unprognostic (1.31e-1)" "unprognostic (2.35e-2)" "unprognostic (3.74e-1)" "unprognostic (9.62e-3)" "unprognostic (2.91e-2)" "unprognostic (9.88e-3)" "unprognostic (3.65e-1)" "unprognostic (1.51e-2)" "potential prognostic unfavorable (2.66e-4)" "unprognostic (1.42e-2)" "unprognostic (5.31e-2)" "unprognostic (3.13e-3)" "potential prognostic unfavorable (1.18e-5)" "potential prognostic unfavorable (8.02e-4)" "unprognostic (1.06e-2)" "potential prognostic unfavorable (1.73e-4)" "unprognostic (6.98e-2)" "unprognostic (2.03e-1)" "unprognostic (1.50e-1)" "unprognostic (3.86e-2)" "unprognostic (1.34e-1)" "potential prognostic unfavorable (7.95e-4)" "unprognostic (8.31e-3)" "unprognostic (3.74e-2)" "unprognostic (2.86e-1)" "unprognostic (9.17e-2)" "unprognostic (4.90e-3)" "unprognostic (7.58e-2)" "unprognostic (3.46e-2)" "potential prognostic unfavorable (1.81e-4)" "unprognostic (4.23e-2)" SQOR "CGI-44, SQR, SQRDL" ENSG00000137767 "Sulfide quinone oxidoreductase" Q9Y6N5 15 45631148-45691281 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 196.7" "Cell type enhanced" "Detected in many" "Colonocytes: 339.0;Enteric stem cells: 178.7;Enteric transient amplifying cells: 197.8;Esophageal apical cells: 685.3;Esophageal suprabasal cells: 203.0;Neutrophil progenitors: 148.6;Neutrophils: 185.9" "Group enriched" "Detected in many" 6 "central nervous system macrophage: 53.3;endothelial cell: 38.0;fibroblast: 18.8;leukocyte: 42.3;pericyte: 18.3;vascular associated smooth muscle cell: 23.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017079, HPA041589" Enhanced Supported Mitochondria NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 17: Intestine - Digestion" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 7 Mitochondria "HPA017079: , HPA041589: " "unprognostic (3.14e-1)" "potential prognostic unfavorable (4.58e-5)" "unprognostic (8.28e-3)" "unprognostic (9.88e-2)" "unprognostic (5.20e-3)" "unprognostic (1.22e-2)" "unprognostic (7.87e-2)" "unprognostic (1.82e-2)" "unprognostic (2.31e-1)" "potential prognostic favorable (4.65e-5)" "unprognostic (9.33e-2)" "unprognostic (3.22e-1)" "unprognostic (1.54e-2)" "potential prognostic unfavorable (6.89e-7)" "unprognostic (3.62e-2)" "unprognostic (4.26e-2)" "unprognostic (1.49e-2)" "unprognostic (9.40e-2)" "unprognostic (1.37e-2)" "potential prognostic unfavorable (4.91e-5)" "unprognostic (7.73e-2)" "unprognostic (2.03e-1)" "unprognostic (1.04e-1)" "unprognostic (5.39e-2)" "unprognostic (1.29e-1)" "unprognostic (2.45e-2)" "unprognostic (5.95e-2)" "unprognostic (5.20e-2)" "unprognostic (6.39e-2)" SQSTM1 "A170, OSIL, p60, p62, p62B, PDB3" ENSG00000161011 "Sequestosome 1" Q13501 5 179806398-179838078 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Autophagy, Differentiation, Immunity" "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 992.1" "Cell type enhanced" "Detected in all" "Colonocytes: 455.7;Goblet cells: 340.9;Ocular epithelial cells: 289.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004587, HPA064165, HPA068843" Supported Supported Vesicles,Cytosol No No 81000 "Cluster 21: Neutrophils - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 7: Liver cancer - Metabolism" "Cluster 65: Non-specific - Cell growth & division" 386 "Vesicles, Cytosol" "CAB004587: , HPA064165: , HPA068843: " "unprognostic (6.20e-2)" "unprognostic (2.11e-2)" "unprognostic (8.40e-2)" "unprognostic (2.59e-1)" "unprognostic (1.27e-1)" "unprognostic (3.07e-2)" "unprognostic (2.44e-2)" "unprognostic (8.04e-3)" "unprognostic (6.67e-2)" "unprognostic (4.49e-2)" "potential prognostic favorable (8.99e-4)" "unprognostic (1.63e-1)" "unprognostic (2.66e-3)" "potential prognostic unfavorable (5.76e-6)" "unprognostic (1.56e-1)" "unprognostic (6.20e-2)" "unprognostic (1.59e-1)" "unprognostic (2.95e-2)" "unprognostic (1.06e-1)" "unprognostic (4.41e-3)" "unprognostic (2.99e-3)" "unprognostic (1.57e-1)" "unprognostic (4.14e-1)" "unprognostic (4.89e-1)" "unprognostic (1.82e-2)" "unprognostic (2.92e-2)" "unprognostic (1.54e-1)" "unprognostic (7.49e-2)" "unprognostic (3.79e-2)" "unprognostic (1.45e-1)" "unprognostic (2.74e-1)" SRA1 "SRA, STRAA1" ENSG00000213523 "Steroid receptor RNA activator 1" Q9HD15 5 140537340-140557677 "Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" "Activator, Receptor, Ribonucleoprotein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 277.2;Syncytiotrophoblasts: 240.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044598, HPA050153" Approved Supported "Nucleoplasm,Microtubules,Cytokinetic bridge,Primary cilium,Cytosol" Yes NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - DNA binding" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 3 Nucleoplasm "Microtubules, Cytokinetic bridge, Primary cilium, Cytosol" "HPA044598: , HPA050153: " "unprognostic (9.11e-2)" "unprognostic (4.57e-2)" "potential prognostic unfavorable (8.48e-4)" "unprognostic (6.14e-3)" "unprognostic (1.61e-1)" "unprognostic (1.73e-1)" "unprognostic (4.06e-2)" "unprognostic (1.24e-1)" "unprognostic (8.54e-2)" "unprognostic (4.32e-2)" "potential prognostic unfavorable (9.86e-5)" "unprognostic (3.34e-2)" "unprognostic (5.12e-3)" "unprognostic (4.44e-2)" "unprognostic (9.70e-3)" "unprognostic (9.16e-3)" "unprognostic (3.12e-1)" "unprognostic (2.35e-1)" "unprognostic (2.18e-2)" "unprognostic (9.39e-2)" "unprognostic (1.63e-1)" "unprognostic (2.88e-3)" "unprognostic (1.02e-1)" "unprognostic (2.39e-3)" "unprognostic (2.71e-1)" "unprognostic (3.73e-1)" "unprognostic (1.17e-1)" "unprognostic (1.96e-1)" "unprognostic (2.33e-1)" "unprognostic (1.22e-1)" "unprognostic (1.14e-1)" SRARP "C1orf64, ERRF, MGC24047" ENSG00000183888 "Steroid receptor associated and regulated protein" Q8NEQ6 1 16004236-16008807 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.9;breast: 4.8;salivary gland: 2.8" "Group enriched" "Detected in some" 5 "Breast hormone-responsive cells: 47.3;Conjunctival goblet cells: 73.8;Epididymal clear cells: 91.9;Respiratory ionocytes: 63.5;Salivary duct cells: 24.7" "Cell type enriched" "Detected in some" 8 "endothelial cell: 81.0" "Group enriched" "Detected in some" 4 "Breast Invasive Carcinoma (TCGA): 15.3;Prostate Adenocarcinoma (TCGA): 11.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.6" "Lineage enriched" "Detected in single" 7 "granulocytes: 1.6" "Cancer enriched" "Detected in some" 5 "breast cancer: 7.9" "Breast - Breast glandular cells, Kidney - Intercalated cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026676 Uncertain Approved Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 47: Endothelial cells - Vasculature" "Cluster 27: Breast cancer - Unknown function" "Cluster 104: Brain endothelial cells - Blood brain barrier" 4 Nucleoplasm "HPA026676: " "unprognostic (7.92e-2)" "unprognostic (6.97e-2)" "unprognostic (1.79e-3)" "unprognostic (3.36e-1)" "unprognostic (9.51e-2)" "unprognostic (1.51e-1)" "unprognostic (2.27e-2)" "unprognostic (9.71e-3)" SRBD1 FLJ10379 ENSG00000068784 "S1 RNA binding domain 1" Q8N5C6 2 45388680-45612165 "Essential proteins, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 267.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030567, HPA030568" Approved Approved Mitochondria,Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 22: Epididymis - Mixed function" "Cluster 36: Choroid plexus - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 8 "Mitochondria, Cytosol" "HPA030567: , HPA030568: " "unprognostic (1.13e-1)" "unprognostic (1.94e-2)" "unprognostic (2.17e-1)" "unprognostic (1.64e-2)" "unprognostic (3.05e-3)" "unprognostic (1.99e-1)" "unprognostic (2.98e-2)" "unprognostic (1.24e-2)" "unprognostic (1.08e-1)" "unprognostic (5.00e-2)" "potential prognostic favorable (1.01e-7)" "unprognostic (2.95e-3)" "unprognostic (1.25e-1)" "unprognostic (4.43e-3)" "unprognostic (6.86e-2)" "unprognostic (2.65e-2)" "unprognostic (1.10e-1)" "unprognostic (3.08e-2)" "unprognostic (3.56e-1)" "unprognostic (1.04e-1)" "unprognostic (3.28e-2)" "unprognostic (1.08e-1)" "unprognostic (4.89e-2)" "unprognostic (2.29e-1)" "unprognostic (9.13e-2)" "unprognostic (3.68e-1)" "unprognostic (1.94e-1)" "unprognostic (3.32e-1)" "unprognostic (3.78e-1)" "unprognostic (1.48e-2)" "unprognostic (3.66e-1)" SRC "ASV, c-src, SRC1" ENSG00000197122 "SRC proto-oncogene, non-receptor tyrosine kinase" P12931 20 37344685-37406050 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell adhesion, Cell cycle, Host-virus interaction, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 82.5;Foveolar cells: 96.8;Megakaryocytes: 173.1;Platelets: 119.8;Urothelial cells: 121.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.9" "Group enriched" "Detected in many" 4 "dendritic cells: 1.0;monocytes: 1.9" "Low cancer specificity" "Detected in all" "Spleen - Macrophages, Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004023, HPA030875" Approved Supported "Vesicles,Plasma membrane,Cell Junctions" NA NA 1700000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 17: Intestine - Digestion" "Cluster 29: Forebrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 69: Urothelial cells - Basic cellular functions" 220 "Vesicles, Plasma membrane, Cell Junctions" "CAB004023: , HPA030875: " "unprognostic (1.20e-1)" "unprognostic (3.66e-2)" "unprognostic (6.36e-2)" "unprognostic (1.40e-3)" "unprognostic (2.16e-1)" "unprognostic (2.57e-1)" "unprognostic (4.56e-1)" "unprognostic (1.45e-2)" "unprognostic (2.42e-1)" "unprognostic (3.26e-1)" "unprognostic (1.08e-2)" "unprognostic (6.32e-3)" "unprognostic (1.48e-1)" "validated prognostic unfavorable (2.14e-4)" "validated prognostic unfavorable (3.05e-5)" "unprognostic (3.55e-2)" "unprognostic (1.19e-2)" "unprognostic (3.20e-2)" "unprognostic (6.00e-2)" "unprognostic (8.52e-3)" "unprognostic (3.78e-1)" "unprognostic (1.82e-2)" "unprognostic (1.52e-2)" "unprognostic (2.98e-2)" "unprognostic (1.28e-2)" "unprognostic (2.58e-1)" "unprognostic (3.70e-2)" "unprognostic (2.12e-2)" "unprognostic (7.89e-2)" "unprognostic (1.48e-1)" "unprognostic (5.15e-3)" SRCAP "DOMO1, KIAA0309, SWR1" ENSG00000080603 "Snf2 related CREBBP activator protein" Q6ZRS2 16 30698209-30741409 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Activator, Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 17.5;Bergmann glia: 14.9;Choroid plexus epithelial cells: 26.0;Ependymal cells: 16.9;Epicardial cells: 15.9;Microglia: 27.7;Oligodendrocytes: 16.3;Tuft cells: 23.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028929 Approved Supported "Nucleoplasm,Nuclear bodies,Golgi apparatus" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 54: Non-specific - Transcription" "Cluster 22: Non-specific - Basic cellular functions" 29 Nucleoplasm "Nuclear bodies, Golgi apparatus" "HPA028929: " "unprognostic (2.91e-1)" "unprognostic (5.80e-2)" "unprognostic (3.14e-1)" "unprognostic (4.99e-2)" "unprognostic (2.73e-1)" "unprognostic (1.41e-1)" "unprognostic (5.28e-2)" "unprognostic (1.66e-1)" "unprognostic (1.20e-2)" "unprognostic (4.58e-3)" "potential prognostic favorable (1.47e-5)" "unprognostic (6.35e-3)" "unprognostic (2.15e-1)" "unprognostic (1.06e-1)" "unprognostic (1.31e-1)" "unprognostic (3.51e-1)" "unprognostic (1.39e-1)" "unprognostic (4.30e-2)" "unprognostic (4.60e-2)" "unprognostic (7.90e-2)" "unprognostic (4.16e-1)" "unprognostic (1.24e-1)" "unprognostic (6.27e-3)" "unprognostic (1.15e-1)" "unprognostic (2.23e-2)" "unprognostic (3.82e-1)" "unprognostic (2.15e-1)" "unprognostic (3.05e-1)" "unprognostic (1.46e-1)" "unprognostic (1.71e-2)" "unprognostic (3.92e-2)" SRCIN1 "KIAA1684, p140Cap, SNIP" ENSG00000277363 "SRC kinase signaling inhibitor 1" Q9C0H9 17 38530031-38605952 "Predicted intracellular proteins" Exocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 76.5" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 99.8;Brain inhibitory neurons: 61.1;Ependymal cells: 65.0;Oligodendrocytes: 353.1;Other brain neurons: 59.4" "Cell type enhanced" "Detected in all" "oligodendrocyte: 442.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 6.9" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Lung - Respiratory ciliated cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009701, HPA063795" Enhanced Approved "Cell Junctions" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 6: Non-specific - Immune response" "Cluster 27: Breast cancer - Unknown function" "Cluster 80: Oligodendrocytes - Myelination" 9 "Cell Junctions" "HPA009701: , HPA063795: " "unprognostic (4.58e-2)" "unprognostic (1.95e-1)" "unprognostic (3.21e-1)" "unprognostic (8.15e-2)" "unprognostic (5.70e-2)" "unprognostic (8.17e-2)" "unprognostic (1.32e-1)" "unprognostic (1.95e-2)" "unprognostic (3.78e-1)" "unprognostic (7.55e-2)" "unprognostic (8.57e-2)" "unprognostic (1.83e-3)" "unprognostic (1.39e-2)" "unprognostic (2.98e-2)" "unprognostic (4.75e-2)" "unprognostic (1.37e-2)" "unprognostic (7.27e-2)" "unprognostic (3.42e-2)" "unprognostic (8.39e-2)" "unprognostic (1.62e-1)" "unprognostic (7.14e-2)" "unprognostic (3.23e-2)" "unprognostic (2.14e-2)" "unprognostic (2.42e-2)" SRD5A1 ENSG00000145545 "Steroid 5 alpha-reductase 1" P18405 5 6633427-6674386 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins" "Differentiation, Lipid metabolism, Sexual differentiation" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 27.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 81.8;Esophageal basal cells: 186.0;Esophageal suprabasal cells: 163.0;Hepatocytes: 169.5;Suprabasal keratinocytes: 116.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.4" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Skeletal muscle - Fibroblasts, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051402 Approved NA NA "Cluster 41: Basophils - Unknown function" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 37: Neurons - Mixed function" "Cluster 29: Non-specific - Unknown function" "Cluster 85: Squamous epithelial cells - Keratinization" 1 "HPA051402: " "unprognostic (1.50e-1)" "unprognostic (2.98e-3)" "unprognostic (1.79e-1)" "unprognostic (1.19e-1)" "unprognostic (1.25e-2)" "unprognostic (2.23e-1)" "unprognostic (9.67e-2)" "unprognostic (9.82e-3)" "unprognostic (3.14e-2)" "unprognostic (2.37e-1)" "potential prognostic favorable (7.35e-6)" "unprognostic (4.90e-3)" "unprognostic (1.99e-1)" "unprognostic (5.41e-2)" "unprognostic (2.09e-2)" "unprognostic (3.23e-2)" "unprognostic (8.32e-2)" "unprognostic (1.58e-1)" "unprognostic (9.71e-2)" "unprognostic (3.56e-2)" "unprognostic (2.71e-1)" "unprognostic (1.19e-2)" "potential prognostic unfavorable (1.06e-4)" "unprognostic (1.01e-1)" "unprognostic (5.51e-2)" "unprognostic (1.47e-2)" "unprognostic (1.37e-1)" "unprognostic (4.25e-1)" "unprognostic (1.27e-1)" "unprognostic (7.99e-2)" "unprognostic (9.38e-3)" SRD5A2 ENSG00000277893 "Steroid 5 alpha-reductase 2" P31213 2 31522480-31580938 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Differentiation, Lipid metabolism, Sexual differentiation" Oxidoreductase "Cancer-related genes, Disease variant, FDA approved drug targets, Pseudohermaphroditism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "epididymis: 22.2;fallopian tube: 19.2;liver: 56.8;prostate: 15.7;seminal vesicle: 17.0" "Cell type enhanced" "Detected in some" "Early spermatids: 96.6;Endometrial ciliated cells: 35.2;Epididymal efferent duct ciliated cells: 30.6;Epididymal principal cells: 47.3;Fallopian tube ciliated cells: 89.8;Hepatocytes: 43.2;Late spermatids: 84.7;Prostatic club cells: 144.0;Prostatic hillock cells: 38.0;Respiratory ciliated cells: 38.8" "Group enriched" "Detected in some" 4 "central nervous system macrophage: 1.2;cerebellar inhibitory: 4.6" "Group enriched" "Detected in some" 4 "Liver Hepatocellular Carcinoma (TCGA): 5.2;Prostate Adenocarcinoma (TCGA): 4.6" "Region enriched" "Detected in single" 13 "midbrain: 2.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 46: Brainstem - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 107: Ciliated cells - Cilia assembly & function" 5 "unprognostic (1.93e-1)" "unprognostic (1.72e-3)" "unprognostic (2.02e-2)" "unprognostic (1.87e-3)" "unprognostic (3.35e-2)" SRD5A3 "FLJ13352, SRD5A2L, SRD5A2L1" ENSG00000128039 "Steroid 5 alpha-reductase 3" Q9H8P0 4 55346213-55373100 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism" Oxidoreductase "Cataract, Congenital disorder of glycosylation, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 5.7;Bergmann glia: 5.2;Brain excitatory neurons: 17.9;Brain inhibitory neurons: 22.5;Loop of henle epithelial cells: 5.7;Microglia: 9.2;Oligodendrocyte progenitor cells: 12.8;Oligodendrocytes: 37.8;Other brain neurons: 15.8;Papillary tip epithelial cells: 14.4;Podocytes: 9.5;Renal collecting duct principal cells: 5.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027006 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 27: Breast cancer - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" "Plasma membrane, Cytosol" "HPA027006: " "unprognostic (1.44e-1)" "unprognostic (1.79e-3)" "unprognostic (2.85e-2)" "unprognostic (2.94e-1)" "unprognostic (3.71e-3)" "unprognostic (1.17e-1)" "potential prognostic unfavorable (1.44e-5)" "unprognostic (2.30e-2)" "unprognostic (2.52e-2)" "unprognostic (7.51e-2)" "potential prognostic unfavorable (9.45e-9)" "unprognostic (8.29e-3)" "unprognostic (4.87e-2)" "potential prognostic unfavorable (7.94e-6)" "unprognostic (3.67e-3)" "unprognostic (2.99e-3)" "potential prognostic unfavorable (8.68e-4)" "unprognostic (3.35e-2)" "unprognostic (2.37e-1)" "unprognostic (7.15e-2)" "unprognostic (1.03e-1)" "unprognostic (5.88e-3)" "unprognostic (1.00e-1)" "unprognostic (7.41e-2)" "unprognostic (1.60e-1)" "unprognostic (2.41e-1)" "unprognostic (1.12e-1)" "unprognostic (1.68e-1)" "unprognostic (1.37e-1)" "unprognostic (2.98e-2)" "unprognostic (3.06e-1)" SREBF1 "bHLHd1, SREBP-1c, SREBP1, SREBP1a" ENSG00000072310 "Sterol regulatory element binding transcription factor 1" P36956 17 17810399-17837002 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism, Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 150.1;liver: 113.9" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 274.0;Breast lactating cells: 220.9" "Cell type enhanced" "Detected in all" "astrocyte: 162.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043343, HPA069227" Uncertain Enhanced Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 70: Non-specific - Protein processing" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 69: Urothelial cells - Basic cellular functions" 34 Nucleoplasm "HPA043343: , HPA069227: " "unprognostic (1.03e-1)" "unprognostic (2.83e-1)" "unprognostic (2.54e-1)" "unprognostic (9.12e-3)" "unprognostic (2.18e-1)" "unprognostic (3.05e-1)" "unprognostic (2.39e-1)" "unprognostic (4.14e-2)" "unprognostic (1.92e-2)" "unprognostic (1.42e-2)" "potential prognostic favorable (4.86e-5)" "unprognostic (1.51e-2)" "unprognostic (1.42e-1)" "unprognostic (1.58e-2)" "unprognostic (1.70e-1)" "unprognostic (5.97e-2)" "unprognostic (3.25e-1)" "unprognostic (8.75e-2)" "unprognostic (1.57e-1)" "unprognostic (2.15e-2)" "unprognostic (2.59e-2)" "unprognostic (1.03e-2)" "unprognostic (2.92e-2)" "unprognostic (1.69e-1)" "unprognostic (2.16e-1)" "unprognostic (1.24e-1)" "unprognostic (4.35e-1)" "unprognostic (1.46e-1)" "unprognostic (9.25e-2)" "unprognostic (1.37e-1)" "unprognostic (2.26e-1)" SREBF2 "bHLHd2, SREBP2" ENSG00000198911 "Sterol regulatory element binding transcription factor 2" Q12772 22 41833079-41907307 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031962, HPA031963" Approved Supported "Nucleoplasm,Endoplasmic reticulum,Vesicles" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 36 "Nucleoplasm, Vesicles" "Endoplasmic reticulum" "HPA031962: , HPA031963: " "unprognostic (1.68e-1)" "unprognostic (7.41e-2)" "unprognostic (1.44e-1)" "unprognostic (3.44e-2)" "unprognostic (2.75e-1)" "unprognostic (2.56e-2)" "unprognostic (9.00e-3)" "unprognostic (4.81e-2)" "unprognostic (6.20e-2)" "unprognostic (5.81e-2)" "potential prognostic favorable (8.85e-4)" "unprognostic (1.75e-1)" "unprognostic (1.04e-1)" "unprognostic (9.97e-2)" "unprognostic (5.41e-2)" "unprognostic (5.53e-2)" "unprognostic (3.33e-1)" "unprognostic (1.83e-1)" "potential prognostic favorable (6.46e-4)" "unprognostic (5.59e-2)" "unprognostic (1.68e-1)" "unprognostic (3.58e-1)" "unprognostic (3.44e-1)" "unprognostic (1.45e-1)" "unprognostic (2.36e-2)" "unprognostic (6.61e-2)" "unprognostic (5.17e-2)" "unprognostic (1.14e-1)" "unprognostic (8.22e-2)" "unprognostic (8.73e-2)" "unprognostic (9.92e-2)" SREK1 "DKFZp564B176, SFRS12, SRrp508, SRrp86" ENSG00000153914 "Splicing regulatory glutamic acid and lysine rich protein 1" Q8WXA9 5 66139971-66183615 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "HPA037673, HPA037674, HPA059332" Enhanced Enhanced "Nucleoplasm,Nuclear speckles" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 56: Non-specific - Sensory perception" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 40 "Nucleoplasm, Nuclear speckles" "HPA037673: , HPA037674: , HPA059332: " "unprognostic (3.86e-2)" "unprognostic (2.74e-1)" "unprognostic (1.28e-1)" "unprognostic (4.13e-2)" "unprognostic (2.09e-2)" "unprognostic (8.16e-2)" "unprognostic (8.47e-2)" "unprognostic (6.68e-3)" "potential prognostic unfavorable (4.61e-4)" "unprognostic (1.98e-1)" "unprognostic (1.77e-2)" "unprognostic (3.76e-3)" "unprognostic (3.01e-1)" "unprognostic (2.46e-2)" "unprognostic (1.91e-1)" "unprognostic (5.48e-2)" "unprognostic (1.82e-1)" "unprognostic (6.62e-2)" "unprognostic (2.53e-1)" "unprognostic (2.81e-1)" "unprognostic (8.03e-3)" "unprognostic (3.23e-2)" "unprognostic (6.98e-2)" "unprognostic (1.71e-1)" "unprognostic (1.23e-3)" "unprognostic (3.76e-2)" "unprognostic (1.46e-1)" "unprognostic (2.60e-1)" "unprognostic (3.43e-2)" "unprognostic (2.09e-1)" SREK1IP1 "FLJ36754, P18SRP, SFRS12IP1" ENSG00000153006 "SREK1 interacting protein 1" Q8N9Q2 5 64718148-64768691 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 421.6;Esophageal apical cells: 966.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045677, HPA062853" Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 84: Apical squamous epithelium - Cornification" 30 "Nucleoplasm, Nucleoli" "HPA045677: , HPA062853: " "unprognostic (1.36e-1)" "unprognostic (5.69e-2)" "unprognostic (1.89e-1)" "unprognostic (5.21e-2)" "unprognostic (1.86e-1)" "unprognostic (4.51e-2)" "unprognostic (3.93e-1)" "unprognostic (1.16e-1)" "unprognostic (4.00e-2)" "potential prognostic favorable (2.81e-5)" "unprognostic (4.79e-3)" "unprognostic (3.47e-1)" "potential prognostic unfavorable (2.42e-4)" "unprognostic (7.47e-2)" "unprognostic (1.13e-3)" "unprognostic (8.38e-2)" "unprognostic (9.11e-2)" "unprognostic (6.26e-2)" "unprognostic (7.33e-2)" "unprognostic (1.35e-2)" "unprognostic (2.91e-1)" "potential prognostic unfavorable (5.06e-5)" "unprognostic (1.26e-1)" "unprognostic (2.53e-1)" "unprognostic (9.94e-2)" "unprognostic (8.15e-2)" "unprognostic (5.12e-2)" "unprognostic (3.81e-2)" "unprognostic (1.76e-3)" "unprognostic (7.47e-2)" SRF MCM1 ENSG00000112658 "Serum response factor" P11831 6 43171269-43181506 "Essential proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 80.0;Breast secretory cells: 68.8;Epididymal basal cells: 117.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Colon - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001819, CAB005416" Supported Supported Nucleoplasm NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 51: Neurons - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 62: Smooth muscle cells - Muscle contraction" 33 Nucleoplasm "CAB005416: , HPA001819: " "unprognostic (2.14e-2)" "unprognostic (2.75e-2)" "unprognostic (6.00e-2)" "unprognostic (1.04e-1)" "unprognostic (7.61e-2)" "unprognostic (6.08e-2)" "unprognostic (2.02e-1)" "unprognostic (1.54e-3)" "unprognostic (1.28e-1)" "unprognostic (9.56e-2)" "unprognostic (2.71e-3)" "unprognostic (2.56e-2)" "unprognostic (5.00e-2)" "unprognostic (1.26e-2)" "unprognostic (5.97e-3)" "unprognostic (5.85e-2)" "unprognostic (2.46e-2)" "unprognostic (1.03e-1)" "unprognostic (1.63e-2)" "unprognostic (7.69e-2)" "unprognostic (9.08e-2)" "unprognostic (2.45e-1)" "unprognostic (8.49e-2)" "unprognostic (4.06e-1)" "unprognostic (9.19e-2)" "unprognostic (5.64e-3)" "unprognostic (7.82e-2)" "unprognostic (2.39e-1)" "unprognostic (3.55e-1)" "unprognostic (7.50e-3)" "unprognostic (1.34e-1)" SRFBP1 "BUD22, FLJ25286, p49, Rlb1, STRAP" ENSG00000151304 "Serum response factor binding protein 1" Q8NEF9 5 121961975-122075570 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042737 Approved Approved "Nucleoli rim" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 17: Non-specific - RNA processing" 16 "Nucleoli rim" "HPA042737: " "unprognostic (1.09e-1)" "unprognostic (5.56e-2)" "unprognostic (1.97e-1)" "unprognostic (5.14e-2)" "unprognostic (4.63e-1)" "unprognostic (4.10e-2)" "unprognostic (3.29e-1)" "unprognostic (3.19e-2)" "unprognostic (1.67e-1)" "potential prognostic unfavorable (5.26e-4)" "potential prognostic favorable (1.56e-6)" "unprognostic (2.61e-2)" "unprognostic (7.56e-2)" "unprognostic (5.64e-3)" "unprognostic (1.95e-1)" "unprognostic (7.32e-2)" "unprognostic (1.33e-2)" "unprognostic (1.89e-1)" "unprognostic (2.15e-1)" "unprognostic (4.22e-3)" "potential prognostic unfavorable (1.10e-4)" "unprognostic (1.37e-3)" "unprognostic (1.69e-2)" "unprognostic (1.76e-1)" "unprognostic (2.07e-3)" "unprognostic (9.89e-2)" "unprognostic (8.07e-3)" "unprognostic (9.30e-2)" "unprognostic (2.49e-1)" "unprognostic (2.62e-2)" "unprognostic (1.90e-1)" SRGAP1 "ARHGAP13, KIAA1304" ENSG00000196935 "SLIT-ROBO Rho GTPase activating protein 1" Q7Z6B7 12 63843761-64162217 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "GTPase activation" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bergmann glia: 633.1;Podocytes: 1387.8" "Cell type enhanced" "Detected in all" "Bergmann glia: 654.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052416, HPA078079" Uncertain Approved "Centrosome,Basal body,Cytosol" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 13 Cytosol "Centrosome, Basal body" "HPA052416: , HPA078079: " "unprognostic (1.64e-1)" "potential prognostic unfavorable (9.56e-4)" "unprognostic (4.29e-2)" "unprognostic (7.22e-2)" "unprognostic (2.93e-1)" "unprognostic (5.13e-2)" "unprognostic (2.36e-1)" "unprognostic (7.83e-2)" "unprognostic (9.12e-2)" "unprognostic (1.03e-1)" "unprognostic (3.20e-1)" "unprognostic (2.16e-2)" "potential prognostic unfavorable (2.81e-6)" "unprognostic (1.83e-1)" "potential prognostic unfavorable (3.96e-6)" "unprognostic (2.02e-2)" "unprognostic (4.10e-2)" "unprognostic (1.66e-1)" "potential prognostic unfavorable (3.98e-5)" "unprognostic (5.51e-2)" "unprognostic (4.68e-3)" "potential prognostic unfavorable (9.01e-4)" "unprognostic (1.75e-1)" "unprognostic (1.28e-1)" "unprognostic (4.39e-2)" "unprognostic (1.65e-2)" "unprognostic (2.97e-2)" "unprognostic (2.98e-1)" "unprognostic (2.71e-1)" "potential prognostic unfavorable (9.13e-5)" SRGAP2 "ARHGAP34, FNBP2, KIAA0456, SRGAP2A" ENSG00000266028 "SLIT-ROBO Rho GTPase activating protein 2" O75044 1 206203346-206464436 "Disease related genes, Predicted intracellular proteins" Neurogenesis "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 122.7" "Group enriched" "Detected in many" 5 "Microglia: 2480.3;Podocytes: 1255.4" "Cell type enriched" "Detected in all" 4 "central nervous system macrophage: 2914.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028191, HPA028196, HPA078079" Approved Uncertain "Centrosome,Basal body,Cytosol" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 2: Non-specific - Mixed function" "Cluster 25: Non-specific - Transcription" "Cluster 69: Skin cancer - ECM organization" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 19 Cytosol "Centrosome, Basal body" "HPA028191: , HPA028196: , HPA078079: " "unprognostic (4.17e-2)" "unprognostic (2.36e-2)" "unprognostic (6.23e-2)" "potential prognostic unfavorable (9.29e-4)" "unprognostic (4.32e-2)" "unprognostic (2.84e-3)" "unprognostic (4.75e-2)" "unprognostic (2.73e-1)" "unprognostic (5.81e-3)" "unprognostic (2.11e-3)" "unprognostic (5.52e-2)" "potential prognostic unfavorable (2.26e-4)" "potential prognostic unfavorable (2.21e-4)" "unprognostic (1.44e-2)" "unprognostic (2.09e-1)" "unprognostic (2.74e-3)" "unprognostic (8.29e-2)" "unprognostic (2.84e-1)" "unprognostic (2.33e-3)" "unprognostic (1.56e-2)" "unprognostic (6.87e-2)" "unprognostic (1.66e-3)" "unprognostic (4.26e-3)" "unprognostic (3.71e-1)" "unprognostic (1.18e-1)" "unprognostic (1.03e-1)" "unprognostic (3.05e-1)" "unprognostic (3.33e-2)" SRGAP2B SRGAP2P2 ENSG00000196369 "SLIT-ROBO Rho GTPase activating protein 2B" P0DMP2 1 144887265-145095528 "Predicted intracellular proteins" Neurogenesis "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in all" 4 "brain: 55.9;skin 1: 15.1" "Group enriched" "Detected in many" 4 "Microglia: 457.6;Podocytes: 733.0" "Cell type enriched" "Detected in all" 4 "central nervous system macrophage: 513.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" HPA078079 Approved "Centrosome,Basal body,Cytosol" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 71: Cerebellum - Nervous system development" "Cluster 25: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" "Centrosome, Basal body, Cytosol" "HPA078079: " "unprognostic (1.37e-1)" "unprognostic (2.85e-3)" "unprognostic (9.65e-3)" "unprognostic (4.21e-3)" "unprognostic (1.25e-2)" "unprognostic (1.58e-1)" "unprognostic (3.43e-1)" "unprognostic (1.21e-1)" "unprognostic (3.93e-2)" "potential prognostic favorable (4.77e-5)" "unprognostic (1.68e-3)" "potential prognostic unfavorable (1.32e-5)" "unprognostic (1.18e-2)" "unprognostic (7.00e-2)" "unprognostic (1.60e-2)" "unprognostic (7.04e-2)" "unprognostic (3.07e-1)" "unprognostic (1.47e-2)" "unprognostic (1.65e-3)" "unprognostic (6.34e-2)" "potential prognostic unfavorable (4.98e-4)" "unprognostic (8.20e-2)" "unprognostic (2.04e-1)" "unprognostic (9.39e-3)" "unprognostic (2.92e-1)" "unprognostic (3.13e-2)" "unprognostic (1.89e-1)" "unprognostic (3.51e-2)" "unprognostic (4.46e-3)" SRGAP2C SRGAP2P1 ENSG00000171943 "SLIT-ROBO Rho GTPase activating protein 2C" P0DJJ0 1 121184811-121392874 "Predicted intracellular proteins" Neurogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 33.8" "Cell type enriched" "Detected in many" 7 "Podocytes: 745.9" "Cell type enriched" "Detected in single" 4 "central nervous system macrophage: 2.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells, Spleen - Endothelial cells" HPA078079 Approved "Centrosome,Basal body,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 2: Non-specific - Mixed function" "Cluster 25: Non-specific - Transcription" "Cluster 69: Skin cancer - ECM organization" "Cluster 57: Podocytes - Glomerular filtration" 9 Cytosol "Centrosome, Basal body" "HPA078079: " "unprognostic (6.33e-3)" "unprognostic (2.34e-2)" "unprognostic (1.43e-1)" "unprognostic (3.38e-2)" "unprognostic (1.45e-1)" "unprognostic (1.45e-2)" "unprognostic (2.78e-1)" "unprognostic (3.44e-2)" "unprognostic (7.16e-3)" "unprognostic (3.55e-2)" "unprognostic (3.67e-2)" "unprognostic (4.17e-3)" "potential prognostic unfavorable (4.81e-4)" "unprognostic (1.40e-1)" "unprognostic (7.13e-2)" "unprognostic (2.01e-1)" "unprognostic (2.73e-1)" "unprognostic (1.07e-1)" "unprognostic (2.84e-3)" "unprognostic (2.79e-2)" "unprognostic (5.25e-2)" "unprognostic (1.29e-1)" "unprognostic (7.08e-2)" "unprognostic (1.12e-2)" "unprognostic (2.25e-1)" "unprognostic (6.77e-2)" "unprognostic (1.32e-1)" "unprognostic (2.00e-1)" "unprognostic (8.26e-2)" SRGAP3 "ARHGAP14, KIAA0411, MEGAP, SRGAP2, WRP" ENSG00000196220 "SLIT-ROBO Rho GTPase activating protein 3" O43295 3 8980591-9363053 "Disease related genes, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.0" "Cell type enhanced" "Detected in many" "Ependymal cells: 490.3;Prostatic hillock cells: 690.7;Renal collecting duct principal cells: 462.3;Retinal amacrine cells: 897.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 8.0" "Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary gland ductal cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036959, HPA044074, HPA078079" Enhanced Approved "Centrosome,Basal body,Cytosol" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 2: Neurons - Nucleosome" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 4 Cytosol "Centrosome, Basal body" "HPA036959: , HPA044074: , HPA078079: " "unprognostic (5.24e-3)" "unprognostic (3.39e-2)" "unprognostic (2.66e-1)" "unprognostic (7.71e-2)" "unprognostic (1.49e-1)" "unprognostic (1.93e-1)" "unprognostic (3.98e-2)" "unprognostic (2.93e-1)" "unprognostic (2.40e-2)" "unprognostic (2.19e-2)" "unprognostic (3.82e-3)" "unprognostic (2.31e-2)" "unprognostic (1.03e-1)" "unprognostic (5.08e-2)" "unprognostic (2.59e-2)" "unprognostic (2.83e-3)" "unprognostic (3.66e-1)" "unprognostic (3.66e-2)" "unprognostic (1.25e-2)" "unprognostic (4.56e-2)" "unprognostic (2.27e-2)" "unprognostic (2.52e-1)" "unprognostic (6.37e-2)" "unprognostic (8.35e-2)" SRGN "PPG, PRG, PRG1" ENSG00000122862 Serglycin P10124 10 69088103-69104805 "Plasma proteins, Predicted secreted proteins" "Apoptosis, Biomineralization" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 10 "bone marrow: 7641.5" "Cell type enhanced" "Detected in many" "cDC: 3895.2;Innate lymphoid cells: 2540.3;Kupffer cells: 2514.1;Macrophages: 2654.5;Mast cells: 7093.3;Monocyte progenitors: 5947.1;monocytes: 5940.6;Neutrophil progenitors: 8529.6;Neutrophils: 24234.5;NK-cells: 2105.2;Platelets: 3182.9" "Group enriched" "Detected in many" 5 "central nervous system macrophage: 501.2;endothelial cell: 465.6;leukocyte: 433.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 5737.5" "Lineage enriched" "Detected in all" 5 "granulocytes: 5737.5" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 1066.9;Leukemia: 1148.5" "Breast - Endothelial cells, Heart muscle - Endothelial cells, Liver - Neutrophils, Minor Salivary Gland - Macrophages, Skeletal muscle - Endothelial cells, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000759 Enhanced Supported "Golgi apparatus" "Secreted to blood" Other NA NA 280000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 8 "Golgi apparatus" "HPA000759: " "unprognostic (1.28e-2)" "unprognostic (2.41e-2)" "unprognostic (1.12e-2)" "unprognostic (1.33e-1)" "unprognostic (2.24e-1)" "unprognostic (1.87e-1)" "unprognostic (8.01e-2)" "unprognostic (5.51e-2)" "unprognostic (5.18e-2)" "unprognostic (2.46e-1)" "unprognostic (3.77e-2)" "unprognostic (8.87e-2)" "unprognostic (4.25e-2)" "unprognostic (1.70e-1)" "unprognostic (1.47e-1)" "unprognostic (5.02e-2)" "unprognostic (2.19e-1)" "unprognostic (5.82e-2)" "unprognostic (2.06e-1)" "unprognostic (1.38e-1)" "unprognostic (8.68e-2)" "unprognostic (1.41e-1)" "unprognostic (8.96e-3)" "unprognostic (1.81e-1)" "unprognostic (8.64e-2)" "unprognostic (4.52e-2)" "unprognostic (2.26e-1)" "unprognostic (3.41e-2)" "unprognostic (2.79e-2)" "unprognostic (2.98e-2)" "unprognostic (3.16e-1)" SRI ENSG00000075142 Sorcin P30626 7 88205115-88226993 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 529.7" "Cell type enhanced" "Detected in all" "Colonocytes: 1442.1;Enteric transient amplifying cells: 605.0;Enterocytes: 1216.4;Extravillous trophoblasts: 2163.8;Fallopian tube ciliated cells: 593.9;Respiratory ciliated cells: 618.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019004, HPA073666" Enhanced Approved Nucleoplasm,Cytosol No No 1300000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 17: Intestine - Digestion" "Cluster 21: Non-specific - Metabolism" "Cluster 39: Non-specific - Transcription" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 15 "Nucleoplasm, Cytosol" "HPA019004: , HPA073666: " "unprognostic (4.91e-2)" "unprognostic (2.02e-1)" "unprognostic (1.40e-1)" "unprognostic (2.09e-3)" "unprognostic (3.05e-2)" "unprognostic (9.81e-2)" "unprognostic (1.00e-1)" "unprognostic (2.33e-1)" "potential prognostic unfavorable (9.65e-4)" "unprognostic (3.45e-2)" "potential prognostic favorable (3.24e-5)" "unprognostic (2.43e-1)" "unprognostic (2.09e-2)" "validated prognostic unfavorable (2.63e-4)" "validated prognostic unfavorable (1.85e-4)" "unprognostic (1.36e-1)" "unprognostic (9.07e-3)" "unprognostic (3.65e-2)" "potential prognostic unfavorable (6.67e-4)" "unprognostic (9.79e-2)" "unprognostic (3.85e-2)" "unprognostic (1.44e-3)" "unprognostic (3.30e-1)" "unprognostic (8.28e-2)" "unprognostic (8.69e-2)" "unprognostic (1.76e-1)" "unprognostic (2.26e-1)" "unprognostic (3.20e-3)" "unprognostic (8.39e-3)" "unprognostic (3.96e-2)" "unprognostic (2.69e-1)" SRL SAR ENSG00000185739 Sarcalumenin Q86TD4 16 4189374-4242080 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 24 "heart muscle: 263.9;skeletal muscle: 478.1;tongue: 357.1" "Cell type enriched" "Detected in many" 4 "Myonuclei: 626.6" "Cell type enriched" "Detected in some" 8 "vascular associated smooth muscle cell: 51.9" "Cancer enhanced" "Detected in some" "Thyroid Carcinoma (TCGA): 11.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "lung cancer: 1.4;lymphoma: 3.6;Sarcoma: 2.6" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Breast - Endothelial cells, Heart muscle - Cardiomyocytes, Liver - Vascular endothelial cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 7.0" "HPA041535, HPA045520" Enhanced "Intracellular and membrane" "No annotated function" NA NA 37000 "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 44: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" "HPA041535: , HPA045520: " "unprognostic (1.22e-1)" "unprognostic (8.22e-2)" "unprognostic (1.07e-1)" "unprognostic (3.26e-2)" "unprognostic (1.74e-1)" "unprognostic (5.52e-3)" SRM "SPS1, SRML1" ENSG00000116649 "Spermidine synthase" P19623 1 11054584-11060020 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Polyamine biosynthesis, Spermidine biosynthesis" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 285.0;Esophageal basal cells: 222.2;Extravillous trophoblasts: 207.1;Pancreatic acinar cells: 190.2;Plasma cells: 336.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015746 Approved Approved Nucleoplasm,Cytosol NA NA 48000 "Cluster 14: Non-specific - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 44: Plasma cells - Antibody production & secretion" 3 Nucleoplasm Cytosol "HPA015746: " "unprognostic (8.52e-3)" "unprognostic (5.00e-2)" "unprognostic (1.12e-2)" "unprognostic (4.37e-1)" "unprognostic (1.64e-1)" "unprognostic (3.07e-1)" "unprognostic (1.14e-1)" "unprognostic (7.69e-2)" "unprognostic (9.82e-2)" "unprognostic (3.27e-2)" "validated prognostic unfavorable (9.53e-7)" "validated prognostic unfavorable (1.27e-4)" "unprognostic (1.39e-3)" "validated prognostic unfavorable (1.36e-5)" "validated prognostic unfavorable (4.25e-7)" "potential prognostic unfavorable (1.61e-4)" "unprognostic (1.01e-2)" "unprognostic (1.97e-1)" "unprognostic (2.14e-1)" "unprognostic (6.70e-2)" "potential prognostic favorable (8.40e-4)" "unprognostic (1.25e-1)" "unprognostic (2.79e-1)" "unprognostic (5.85e-2)" "unprognostic (3.63e-2)" "unprognostic (1.82e-2)" "unprognostic (3.38e-1)" "unprognostic (5.58e-2)" "unprognostic (6.95e-2)" "unprognostic (7.18e-3)" "unprognostic (8.47e-2)" SRMS "C20orf148, dJ697K14.1, PTK70, SRM" ENSG00000125508 "Src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites" Q9H3Y6 20 63538489-63547749 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 2.0;lymphoid tissue: 2.1;stomach 1: 2.1" "Cell type enhanced" "Detected in some" "Breast hormone-responsive cells: 4.1;Breast lactating cells: 12.2;Epididymal principal cells: 10.3;Foveolar cells: 9.0;Gastric chief cells: 19.7;Goblet cells: 15.7;Mucous neck cells: 9.0" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 11.7;Gastric cancer: 8.7" "Breast - Breast glandular cells, Skin - Hair cortex cells, Skin - Inner root sheath cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB044668, CAB044669, HPA073987" Uncertain Approved "Intermediate filaments,Actin filaments,Cytosol" No NA "Cluster 60: Stomach - Digestion" "Cluster 6: Non-specific - Immune response" "Cluster 7: Liver cancer - Metabolism" "Cluster 70: Intestinal goblet cells - Mucin production" 21 "Intermediate filaments" "Actin filaments, Cytosol" "CAB044668: , CAB044669: , HPA073987: " "unprognostic (6.29e-3)" "unprognostic (1.58e-2)" "unprognostic (1.96e-1)" "unprognostic (1.47e-2)" "unprognostic (2.92e-2)" "unprognostic (6.13e-2)" "unprognostic (1.73e-1)" "unprognostic (1.21e-2)" "unprognostic (5.69e-3)" "unprognostic (5.72e-2)" "unprognostic (7.49e-2)" "unprognostic (7.43e-3)" "unprognostic (1.69e-1)" "unprognostic (1.80e-3)" "unprognostic (1.94e-1)" "unprognostic (1.33e-1)" SRP14 "ALURBP, MGC14326" ENSG00000140319 "Signal recognition particle 14" P37108 15 40035690-40039181 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial luminal cells: 2197.7;Esophageal apical cells: 2561.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053738, HPA065118" Approved Nucleoplasm,Nucleoli NA NA 59000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 58: Non-specific - Nuclear processes" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 165 Nucleoli Nucleoplasm "HPA053738: , HPA065118: " "unprognostic (3.02e-3)" "unprognostic (7.14e-2)" "unprognostic (6.49e-2)" "unprognostic (7.55e-3)" "unprognostic (3.20e-2)" "unprognostic (2.75e-1)" "unprognostic (6.45e-2)" "unprognostic (2.65e-1)" "unprognostic (3.04e-2)" "unprognostic (1.78e-2)" "potential prognostic favorable (9.05e-6)" "unprognostic (5.41e-3)" "unprognostic (1.11e-1)" "unprognostic (1.78e-2)" "unprognostic (6.01e-3)" "unprognostic (7.99e-3)" "unprognostic (2.62e-1)" "unprognostic (3.15e-3)" "unprognostic (1.48e-1)" "unprognostic (1.48e-1)" "unprognostic (8.98e-2)" "unprognostic (1.89e-1)" "unprognostic (9.52e-2)" "unprognostic (4.77e-2)" "unprognostic (1.81e-1)" "unprognostic (1.92e-1)" "unprognostic (1.66e-1)" "unprognostic (9.42e-2)" "unprognostic (9.56e-3)" "unprognostic (1.96e-3)" "unprognostic (1.98e-3)" SRP19 ENSG00000153037 "Signal recognition particle 19" P09132 5 112861188-112898371 "Essential proteins, Predicted intracellular proteins, Transporters" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 231.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029272, HPA057315" Approved Supported "Nuclear bodies,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 34: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 8: Non-specific - Secretory pathway" 185 Cytosol "Nuclear bodies" "HPA029272: , HPA057315: " "unprognostic (4.87e-2)" "unprognostic (9.10e-3)" "unprognostic (6.77e-2)" "unprognostic (1.65e-1)" "unprognostic (9.54e-2)" "unprognostic (2.58e-1)" "unprognostic (8.27e-3)" "unprognostic (1.66e-1)" "unprognostic (1.48e-2)" "potential prognostic unfavorable (5.26e-4)" "unprognostic (1.55e-2)" "unprognostic (1.48e-1)" "unprognostic (2.74e-3)" "potential prognostic unfavorable (4.77e-6)" "unprognostic (5.11e-2)" "unprognostic (4.23e-3)" "unprognostic (9.81e-2)" "unprognostic (5.13e-2)" "unprognostic (9.68e-2)" "unprognostic (2.20e-1)" "unprognostic (1.10e-1)" "unprognostic (8.99e-2)" "potential prognostic unfavorable (2.76e-4)" "unprognostic (1.08e-1)" "unprognostic (1.38e-1)" "unprognostic (2.93e-3)" "unprognostic (2.88e-2)" "unprognostic (1.02e-1)" "unprognostic (2.79e-1)" "unprognostic (2.40e-3)" "unprognostic (1.33e-1)" SRP54 ENSG00000100883 "Signal recognition particle 54" P61011 14 34981957-35029686 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Hydrolase, Ribonucleoprotein, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Late spermatids: 1633.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Mitotic cells (Spleen), Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048977, HPA062044" Approved Approved Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 54 Cytosol "HPA048977: , HPA062044: " "unprognostic (2.04e-3)" "unprognostic (1.07e-3)" "unprognostic (8.20e-2)" "unprognostic (1.88e-1)" "unprognostic (1.25e-2)" "unprognostic (5.74e-3)" "unprognostic (3.15e-1)" "unprognostic (1.78e-1)" "unprognostic (1.39e-2)" "unprognostic (1.41e-1)" "potential prognostic favorable (1.59e-7)" "unprognostic (6.39e-2)" "unprognostic (8.07e-2)" "potential prognostic unfavorable (5.50e-4)" "unprognostic (7.04e-2)" "unprognostic (2.24e-1)" "unprognostic (3.07e-3)" "unprognostic (1.78e-1)" "unprognostic (1.34e-1)" "unprognostic (1.31e-1)" "unprognostic (5.69e-2)" "unprognostic (1.07e-1)" "unprognostic (1.25e-2)" "unprognostic (1.33e-1)" "unprognostic (1.28e-1)" "unprognostic (4.74e-2)" "unprognostic (9.98e-2)" "unprognostic (2.60e-1)" "unprognostic (2.22e-1)" "unprognostic (7.35e-2)" "unprognostic (3.15e-2)" SRP68 ENSG00000167881 "Signal recognition particle 68" Q9UHB9 17 76038775-76072517 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 301.1;Syncytiotrophoblasts: 208.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in all" 7 "cerebral cortex: 438.2;medulla oblongata: 644.9" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023303, HPA055617" Approved Supported Cytosol NA NA 37000 "Cluster 45: Eosinophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Breast cancer - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 283 Cytosol "HPA023303: , HPA055617: " "unprognostic (3.05e-1)" "unprognostic (1.25e-1)" "unprognostic (9.37e-2)" "unprognostic (3.25e-2)" "unprognostic (2.92e-2)" "unprognostic (1.16e-2)" "unprognostic (3.97e-1)" "unprognostic (3.14e-1)" "unprognostic (1.12e-2)" "potential prognostic unfavorable (1.34e-4)" "potential prognostic favorable (2.45e-5)" "unprognostic (5.97e-3)" "potential prognostic unfavorable (2.84e-5)" "unprognostic (2.72e-3)" "potential prognostic unfavorable (1.89e-4)" "unprognostic (5.90e-2)" "unprognostic (1.24e-3)" "unprognostic (2.38e-1)" "unprognostic (7.86e-3)" "unprognostic (7.68e-2)" "unprognostic (8.82e-2)" "unprognostic (3.06e-2)" "unprognostic (1.09e-2)" "unprognostic (1.65e-2)" "unprognostic (2.29e-2)" "unprognostic (1.20e-2)" "unprognostic (2.48e-1)" "unprognostic (9.69e-2)" "unprognostic (1.75e-1)" "unprognostic (2.26e-1)" "unprognostic (7.11e-2)" SRP72 ENSG00000174780 "Signal recognition particle 72" O76094 4 56467617-56503681 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" Ribonucleoprotein "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034621 Approved NA NA 26000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 61: Non-specific - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 8: Non-specific - Secretory pathway" 221 "HPA034621: " "unprognostic (4.57e-1)" "unprognostic (2.94e-2)" "unprognostic (9.95e-2)" "unprognostic (7.05e-2)" "unprognostic (3.30e-2)" "unprognostic (7.13e-2)" "unprognostic (7.26e-2)" "unprognostic (3.51e-2)" "unprognostic (7.86e-2)" "unprognostic (1.80e-2)" "potential prognostic favorable (1.34e-6)" "unprognostic (9.45e-3)" "unprognostic (2.11e-1)" "potential prognostic unfavorable (5.45e-4)" "unprognostic (4.18e-3)" "unprognostic (1.35e-2)" "unprognostic (3.90e-3)" "unprognostic (1.05e-2)" "unprognostic (6.39e-2)" "unprognostic (1.25e-1)" "unprognostic (2.46e-3)" "unprognostic (1.56e-3)" "unprognostic (3.31e-3)" "unprognostic (1.23e-1)" "unprognostic (2.37e-3)" "unprognostic (1.66e-1)" "unprognostic (3.72e-2)" "unprognostic (1.03e-1)" "unprognostic (5.47e-1)" "unprognostic (2.00e-2)" "unprognostic (7.40e-2)" SRP9 ENSG00000143742 "Signal recognition particle 9" P49458 1 225777813-225790468 "Essential proteins, Predicted intracellular proteins, Transporters" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 682.9;Parietal cells: 606.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 5500 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 45: Non-specific - Nuclear processes" "Cluster 97: Non-specific - Cellular respiration" 267 "unprognostic (1.99e-1)" "potential prognostic unfavorable (4.99e-4)" "unprognostic (2.04e-2)" "unprognostic (3.36e-1)" "unprognostic (7.44e-3)" "unprognostic (6.62e-2)" "unprognostic (1.35e-2)" "unprognostic (1.30e-1)" "unprognostic (2.41e-2)" "unprognostic (3.36e-1)" "potential prognostic favorable (8.08e-6)" "unprognostic (1.41e-1)" "unprognostic (7.97e-2)" "unprognostic (4.41e-2)" "unprognostic (1.19e-1)" "unprognostic (1.11e-2)" "unprognostic (1.22e-2)" "unprognostic (2.81e-2)" "unprognostic (1.21e-1)" "unprognostic (1.43e-2)" "unprognostic (1.84e-2)" "unprognostic (3.72e-2)" "unprognostic (1.80e-1)" "unprognostic (1.22e-1)" "unprognostic (2.30e-1)" "unprognostic (7.59e-2)" "unprognostic (4.29e-2)" "unprognostic (1.63e-1)" "unprognostic (6.49e-2)" "unprognostic (9.43e-2)" "unprognostic (1.44e-1)" SRPK1 SFRSK1 ENSG00000096063 "SRSF protein kinase 1" Q96SB4 6 35832966-35921342 "Enzymes, Predicted intracellular proteins" "Chromosome partition, Differentiation, Host-virus interaction, mRNA processing, mRNA splicing" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 437.4;Late spermatids: 890.5;Neutrophil progenitors: 707.8;Neutrophils: 2212.5;Urothelial cells: 497.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 61.1" "Lineage enriched" "Detected in all" 4 "granulocytes: 61.1" "Low cancer specificity" "Detected in all" "Spleen - Neutrophils_2, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016431, HPA056486" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 53: Neurons - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 24: Neutrophils - Innate immunity signal integration" 155 "Nucleoplasm, Cytosol" "Plasma membrane" "HPA016431: , HPA056486: " "unprognostic (2.30e-1)" "unprognostic (2.00e-3)" "unprognostic (2.73e-1)" "unprognostic (2.67e-3)" "unprognostic (4.37e-2)" "unprognostic (1.96e-2)" "unprognostic (5.19e-2)" "unprognostic (4.92e-2)" "unprognostic (7.91e-2)" "potential prognostic unfavorable (1.58e-4)" "potential prognostic favorable (1.74e-4)" "unprognostic (1.95e-1)" "unprognostic (2.08e-3)" "validated prognostic unfavorable (1.39e-4)" "validated prognostic unfavorable (1.01e-4)" "unprognostic (6.93e-3)" "potential prognostic unfavorable (7.17e-5)" "unprognostic (9.16e-3)" "unprognostic (7.13e-2)" "unprognostic (5.41e-2)" "unprognostic (1.91e-1)" "potential prognostic unfavorable (5.69e-4)" "unprognostic (1.34e-1)" "unprognostic (3.01e-2)" "potential prognostic favorable (2.85e-4)" "unprognostic (2.96e-1)" "unprognostic (3.86e-2)" "unprognostic (5.18e-2)" "unprognostic (5.95e-1)" "unprognostic (6.55e-2)" "unprognostic (1.05e-1)" SRPK2 SFRSK2 ENSG00000135250 "SRSF protein kinase 2" P78362 7 105110704-105399308 "Enzymes, Predicted intracellular proteins" "Differentiation, mRNA processing, mRNA splicing" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 87.6" "Cell type enhanced" "Detected in all" "Early spermatids: 1649.0;Late spermatids: 3787.4;Neutrophils: 2230.6;Sertoli cells: 1647.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015522, HPA020876" Enhanced Supported "Nucleoplasm,Nucleoli,Cytosol,Acrosome,End piece" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 34: Non-specific - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 24: Neutrophils - Innate immunity signal integration" 245 "Nucleoplasm, Cytosol" "Nucleoli, Acrosome, End piece" "HPA015522: , HPA020876: " "unprognostic (1.76e-2)" "unprognostic (1.29e-2)" "unprognostic (6.75e-3)" "unprognostic (1.51e-2)" "unprognostic (3.39e-2)" "unprognostic (3.61e-2)" "unprognostic (3.21e-1)" "unprognostic (3.47e-2)" "unprognostic (2.31e-1)" "potential prognostic unfavorable (3.02e-5)" "potential prognostic favorable (8.81e-5)" "unprognostic (1.12e-1)" "unprognostic (2.31e-1)" "unprognostic (4.81e-2)" "unprognostic (1.50e-2)" "unprognostic (2.22e-2)" "unprognostic (1.68e-1)" "unprognostic (2.33e-1)" "unprognostic (1.05e-1)" "unprognostic (2.50e-2)" "unprognostic (5.34e-2)" "unprognostic (5.02e-2)" "potential prognostic unfavorable (9.25e-4)" "unprognostic (1.77e-1)" "unprognostic (4.08e-2)" "unprognostic (2.20e-1)" "unprognostic (6.96e-2)" "unprognostic (4.53e-1)" "unprognostic (4.88e-2)" "unprognostic (4.84e-2)" "unprognostic (1.67e-1)" SRPK3 "MSSK1, STK23" ENSG00000184343 "SRSF protein kinase 3" Q9UPE1 X 153776412-153785732 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Differentiation, Myogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 198.2;tongue: 71.6" "Cell type enhanced" "Detected in some" "Breast lactating cells: 16.9;Cardiomyocytes: 16.6;Corticotrophs: 24.3;Myonuclei: 53.3;Salivary ionocytes: 11.9;Thymic myoid cells: 95.2" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 14.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Pituitary gland - Corticotropes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 6: Non-specific - Immune response" "Cluster 35: RS4;11 - Unknown function" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 35 "unprognostic (6.39e-2)" "unprognostic (1.83e-3)" "unprognostic (1.46e-1)" "unprognostic (1.42e-1)" "unprognostic (1.22e-1)" "unprognostic (2.00e-1)" "unprognostic (2.41e-1)" "unprognostic (1.93e-1)" "unprognostic (1.09e-1)" "unprognostic (1.69e-1)" "unprognostic (6.42e-2)" "potential prognostic favorable (3.13e-4)" "unprognostic (1.51e-1)" "unprognostic (1.74e-1)" "unprognostic (1.78e-1)" "unprognostic (2.25e-1)" "unprognostic (6.70e-2)" "potential prognostic favorable (9.60e-4)" "unprognostic (1.55e-1)" "unprognostic (4.35e-2)" "unprognostic (1.50e-2)" "unprognostic (3.79e-2)" "unprognostic (2.44e-2)" "unprognostic (6.33e-2)" "unprognostic (2.15e-1)" SRPRA "SR-alpha, Sralpha, SRP-alpha, SRPR" ENSG00000182934 "SRP receptor subunit alpha" P08240 11 126262938-126269144 "Essential proteins, Plasma proteins, Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 202.1;Salivary acinar cells: 170.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Stomach - Chief cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 26000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 70: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 78: Plasma cells - Antibody production & ER-stress response" 58 "unprognostic (1.08e-2)" "potential prognostic unfavorable (4.42e-4)" "unprognostic (7.07e-3)" "unprognostic (1.70e-1)" "unprognostic (3.00e-1)" "unprognostic (2.15e-2)" "unprognostic (4.06e-1)" "unprognostic (3.99e-2)" "unprognostic (6.52e-2)" "potential prognostic favorable (7.38e-4)" "unprognostic (1.21e-1)" "unprognostic (2.96e-1)" "unprognostic (1.14e-1)" "unprognostic (4.84e-2)" "unprognostic (1.68e-2)" "unprognostic (1.26e-1)" "unprognostic (1.88e-1)" "unprognostic (1.59e-2)" "unprognostic (4.04e-1)" "unprognostic (6.15e-3)" "unprognostic (1.46e-1)" "unprognostic (2.99e-1)" "unprognostic (7.51e-2)" "unprognostic (1.58e-1)" "unprognostic (1.70e-1)" "unprognostic (1.06e-1)" "unprognostic (8.00e-2)" "unprognostic (3.22e-2)" "unprognostic (1.31e-1)" SRPRB "APMCF1, SR-beta" ENSG00000144867 "SRP receptor subunit beta" Q9Y5M8 3 133784023-133825772 "Essential proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal suprabasal cells: 149.6;Oocytes: 142.8;Plasma cells: 206.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Stomach - Chief cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011173 Approved Approved "Plasma membrane" NA NA 6000 "Cluster 30: Non-specific - DNA binding" "Cluster 8: Pancreas - Proteolysis" "Cluster 27: Non-specific - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 8: Non-specific - Secretory pathway" 71 "Plasma membrane" "HPA011173: " "unprognostic (2.84e-2)" "potential prognostic unfavorable (3.02e-4)" "unprognostic (1.35e-1)" "unprognostic (1.17e-1)" "unprognostic (5.21e-2)" "unprognostic (2.46e-2)" "unprognostic (1.18e-1)" "unprognostic (3.05e-1)" "unprognostic (1.17e-2)" "unprognostic (5.57e-3)" "unprognostic (4.01e-2)" "unprognostic (2.50e-3)" "unprognostic (7.13e-2)" "validated prognostic unfavorable (4.38e-6)" "validated prognostic unfavorable (5.98e-6)" "unprognostic (5.44e-3)" "unprognostic (1.98e-2)" "unprognostic (3.11e-2)" "unprognostic (7.84e-2)" "unprognostic (1.42e-2)" "unprognostic (1.31e-2)" "unprognostic (1.04e-1)" "unprognostic (1.77e-1)" "unprognostic (8.14e-2)" "unprognostic (6.09e-2)" "unprognostic (8.83e-2)" "unprognostic (2.18e-2)" "unprognostic (2.94e-2)" "unprognostic (2.21e-1)" "unprognostic (1.00e-2)" "unprognostic (1.29e-3)" SRPX "ETX1, SRPX1" ENSG00000101955 "Sushi repeat containing protein X-linked" P78539 X 38149336-38220924 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 206.2" "Cell type enhanced" "Detected in many" "Bergmann glia: 182.5;Decidual stromal cells: 393.5;Epididymal basal cells: 99.8;Fibro-adipogenic progenitors: 94.0;Fibroblasts: 272.9;Granulosa cells: 94.1;Hepatic stellate cells: 193.6;Leydig cells: 80.4;Lymphatic endothelial cells: 89.6;Melanocytes: 80.5;Peritubular myoid cells: 115.8;Schwann cells: 87.4;Vascular endothelial cells: 75.7" "Cell type enhanced" "Detected in many" "astrocyte: 118.8;Bergmann glia: 204.6" "Group enriched" "Detected in all" 5 "Glioblastoma Multiforme (TCGA): 105.0;Skin Cutaneous Melanoma (TCGA): 120.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 49 "plasmacytoid DC: 7.8" "Lineage enriched" "Detected in single" 49 "dendritic cells: 7.8" "Cancer enhanced" "Detected in many" "skin cancer: 188.4" "Heart muscle - Macrophages, Minor Salivary Gland - Macrophages, Prostate - Fibroblasts" "Low region specificity" "Detected in single" "Region enhanced" "Detected in many" "spinal cord: 17.6" "Secreted - unknown location" "Cell adhesion" NA NA 2700000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 44: Non-specific - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 3 "unprognostic (5.84e-2)" "unprognostic (3.05e-1)" "unprognostic (5.48e-2)" "unprognostic (7.82e-2)" "unprognostic (1.21e-2)" "unprognostic (1.11e-1)" "unprognostic (5.42e-2)" "potential prognostic unfavorable (7.51e-4)" "unprognostic (1.41e-3)" "unprognostic (7.76e-3)" "unprognostic (4.66e-3)" "unprognostic (1.89e-1)" "potential prognostic unfavorable (8.06e-8)" "unprognostic (5.06e-2)" "unprognostic (1.67e-3)" "unprognostic (4.26e-1)" "unprognostic (3.00e-1)" "unprognostic (3.49e-1)" "unprognostic (1.71e-1)" "unprognostic (4.09e-2)" "unprognostic (1.53e-2)" "unprognostic (9.10e-2)" "unprognostic (4.65e-1)" "unprognostic (2.07e-2)" "potential prognostic unfavorable (1.08e-4)" "unprognostic (1.19e-1)" "unprognostic (2.32e-1)" "unprognostic (7.53e-3)" "unprognostic (1.41e-1)" "unprognostic (2.76e-2)" "unprognostic (1.46e-2)" SRPX2 SRPUL ENSG00000102359 "Sushi repeat containing protein X-linked 2" O60687 X 100644195-100675788 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 29.6" "Cell type enhanced" "Detected in many" "Adipocytes: 273.3;Esophageal apical cells: 478.6;Fibro-adipogenic progenitors: 190.1;Fibroblasts: 157.8;Hepatic stellate cells: 116.2;Myosatellite cells: 110.0;Prostatic club cells: 94.7;Prostatic hillock cells: 165.2;Somatotrophs: 91.2;Urothelial cells: 252.3" "Group enriched" "Detected in many" 5 "astrocyte: 80.4;fibroblast: 315.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Testis - Endothelial cells" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "midbrain: 1.0;spinal cord: 3.4" HPA038786 Approved "Secreted to blood" "Cell adhesion" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 46: Brainstem - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" "HPA038786: " "unprognostic (3.10e-2)" "unprognostic (7.90e-2)" "unprognostic (1.21e-1)" "unprognostic (1.35e-3)" "unprognostic (2.61e-1)" "unprognostic (1.36e-1)" "unprognostic (3.31e-2)" "unprognostic (9.33e-3)" "unprognostic (4.35e-3)" "unprognostic (8.07e-2)" "potential prognostic unfavorable (5.71e-8)" "unprognostic (5.02e-3)" "potential prognostic unfavorable (1.84e-6)" "unprognostic (1.07e-3)" "unprognostic (1.41e-1)" "unprognostic (7.33e-3)" "unprognostic (1.04e-3)" "unprognostic (1.75e-1)" "unprognostic (6.44e-3)" "unprognostic (7.84e-2)" "unprognostic (7.29e-3)" "unprognostic (1.89e-2)" "unprognostic (1.36e-3)" "unprognostic (7.64e-2)" "unprognostic (1.74e-1)" "potential prognostic favorable (1.59e-4)" "unprognostic (1.22e-3)" "potential prognostic unfavorable (1.24e-4)" "unprognostic (1.21e-1)" "unprognostic (9.27e-2)" "unprognostic (3.45e-1)" SRR "ILV1, ISO1" ENSG00000167720 "Serine racemase" Q9GZT4 17 2303383-2325260 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Allosteric enzyme, Isomerase, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Cardiomyocytes: 103.2;Early primary spermatocytes: 44.4;Epicardial cells: 161.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007529, CAB015343" Approved Approved Vesicles NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 40: Non-specific - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 6 Vesicles "CAB015343: , HPA007529: " "unprognostic (5.61e-2)" "unprognostic (3.71e-2)" "unprognostic (3.43e-2)" "unprognostic (3.92e-2)" "unprognostic (9.38e-2)" "unprognostic (1.51e-2)" "unprognostic (3.01e-1)" "unprognostic (3.41e-1)" "unprognostic (9.57e-3)" "unprognostic (6.54e-2)" "potential prognostic favorable (4.44e-5)" "unprognostic (1.01e-3)" "unprognostic (5.54e-3)" "unprognostic (5.01e-2)" "unprognostic (3.50e-1)" "unprognostic (1.08e-2)" "unprognostic (6.97e-2)" "unprognostic (6.50e-3)" "unprognostic (6.22e-2)" "unprognostic (2.15e-2)" "unprognostic (2.85e-1)" "unprognostic (1.94e-2)" "unprognostic (1.34e-2)" "unprognostic (2.98e-2)" "unprognostic (2.84e-1)" "unprognostic (4.12e-3)" "unprognostic (3.17e-2)" "unprognostic (3.12e-2)" "unprognostic (9.25e-2)" "unprognostic (6.44e-2)" "unprognostic (3.21e-2)" SRRD "HC/HCC, SRR1L" ENSG00000100104 "SRR1 domain containing" Q9UH36 22 26483877-26494658 "Predicted intracellular proteins" "Biological rhythms, Heme biosynthesis" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 83.9;Pancreatic acinar cells: 43.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002945 Uncertain Approved Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 15: Non-specific - Transcription" "Cluster 6: Leukemia - Signal transduction" "Cluster 17: Non-specific - RNA processing" Cytosol "HPA002945: " "unprognostic (2.78e-1)" "unprognostic (1.28e-1)" "unprognostic (1.54e-1)" "unprognostic (2.63e-1)" "unprognostic (5.38e-2)" "unprognostic (1.42e-1)" "unprognostic (1.47e-1)" "unprognostic (4.94e-2)" "unprognostic (8.70e-2)" "unprognostic (1.24e-1)" "unprognostic (3.08e-3)" "potential prognostic favorable (3.39e-4)" "unprognostic (7.74e-2)" "potential prognostic unfavorable (1.07e-6)" "unprognostic (5.60e-3)" "unprognostic (4.12e-2)" "potential prognostic unfavorable (6.61e-4)" "unprognostic (1.71e-1)" "unprognostic (1.35e-2)" "unprognostic (2.48e-1)" "unprognostic (9.97e-3)" "validated prognostic unfavorable (3.72e-4)" "validated prognostic unfavorable (6.39e-4)" "unprognostic (4.64e-2)" "unprognostic (2.60e-2)" "unprognostic (1.87e-2)" "unprognostic (4.13e-2)" "unprognostic (6.74e-2)" "unprognostic (2.18e-1)" "unprognostic (1.48e-3)" "unprognostic (1.12e-2)" SRRM1 "MGC39488, POP101, SRM160" ENSG00000133226 "Serine and arginine repetitive matrix 1" Q8IYB3 1 24631716-24673281 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "mRNA processing, mRNA splicing" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epididymal principal cells: 895.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049941, HPA058612" Supported Enhanced "Nuclear speckles" NA NA 190000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 64: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 20: Non-specific - Transcription regulation" 88 "Nuclear speckles" "HPA049941: , HPA058612: " "unprognostic (2.13e-1)" "unprognostic (2.11e-2)" "unprognostic (5.80e-2)" "unprognostic (1.15e-1)" "unprognostic (1.07e-1)" "unprognostic (9.80e-2)" "unprognostic (6.79e-2)" "unprognostic (3.39e-1)" "unprognostic (8.98e-2)" "unprognostic (1.33e-3)" "unprognostic (6.21e-2)" "unprognostic (1.19e-2)" "unprognostic (1.38e-1)" "potential prognostic unfavorable (1.07e-4)" "unprognostic (7.82e-2)" "unprognostic (2.39e-1)" "unprognostic (5.24e-2)" "unprognostic (1.63e-1)" "unprognostic (1.44e-2)" "unprognostic (1.72e-1)" "unprognostic (6.56e-2)" "unprognostic (1.26e-2)" "unprognostic (1.56e-2)" "unprognostic (1.74e-2)" "unprognostic (3.97e-1)" "unprognostic (9.02e-3)" "unprognostic (5.43e-2)" "unprognostic (7.32e-2)" "unprognostic (1.29e-1)" "unprognostic (1.57e-1)" "unprognostic (5.57e-2)" SRRM2 "Cwc21, KIAA0324, SRL300, SRm300" ENSG00000167978 "Serine/arginine repetitive matrix 2" Q9UQ35 16 2752626-2772538 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Autism spectrum disorder, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 85.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041411, HPA066181" Supported Enhanced "Nuclear speckles" NA NA 20000 "Cluster 21: Neutrophils - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 54: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 114 "Nuclear speckles" "HPA041411: , HPA066181: " "unprognostic (1.88e-1)" "unprognostic (4.44e-2)" "unprognostic (2.83e-1)" "unprognostic (4.11e-2)" "unprognostic (2.30e-1)" "unprognostic (5.94e-2)" "unprognostic (1.57e-1)" "unprognostic (2.29e-1)" "unprognostic (5.86e-2)" "unprognostic (6.35e-2)" "unprognostic (2.40e-1)" "unprognostic (7.48e-3)" "unprognostic (1.73e-1)" "unprognostic (7.00e-3)" "unprognostic (1.23e-1)" "unprognostic (3.55e-2)" "unprognostic (2.28e-1)" "unprognostic (8.49e-2)" "unprognostic (1.39e-3)" "unprognostic (5.93e-2)" "unprognostic (1.24e-1)" "unprognostic (6.25e-3)" "potential prognostic unfavorable (5.27e-4)" "unprognostic (1.76e-1)" "unprognostic (4.45e-1)" "unprognostic (3.00e-2)" "unprognostic (3.27e-2)" "unprognostic (5.95e-2)" "unprognostic (1.07e-1)" "unprognostic (2.22e-1)" "unprognostic (2.78e-2)" SRRM3 FLJ37078 ENSG00000177679 "Serine/arginine repetitive matrix 3" 7 76201896-76287288 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 6 "brain: 77.8;retina: 25.2" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 191.5;Brain excitatory neurons: 230.2;Brain inhibitory neurons: 295.4;Cone photoreceptor cells: 513.4;Gonadotrophs: 143.1;Lactotrophs: 213.2;Other brain neurons: 158.4;Retinal amacrine cells: 403.4;Retinal bipolar cells: 234.3;Retinal ganglion cells: 421.0;Retinal horizontal cells: 356.6;Rod photoreceptor cells: 481.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 1.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Neuroblastoma: 16.6" "Colon - Enteric glia cells, Lung - Fibroblasts_2, Pituitary gland - Lactotropes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019337 Approved "Plasma membrane,Intermediate filaments,Microtubules" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 37: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" "Plasma membrane" "Intermediate filaments, Microtubules" "HPA019337: " "unprognostic (1.18e-1)" "unprognostic (5.49e-2)" "potential prognostic favorable (4.26e-4)" "unprognostic (2.59e-1)" "unprognostic (2.74e-1)" "unprognostic (2.46e-1)" "unprognostic (2.45e-3)" SRRM4 "KIAA1853, nSR100" ENSG00000139767 "Serine/arginine repetitive matrix 4" A7MD48 12 118981541-119163051 "Predicted intracellular proteins" "Differentiation, mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 26 "brain: 44.3;retina: 27.0" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 170.2;Brain excitatory neurons: 330.0;Brain inhibitory neurons: 191.6;Cone photoreceptor cells: 1051.6;Distal convoluted tubule cells: 156.4;Other brain neurons: 158.2;Retinal amacrine cells: 956.6;Retinal bipolar cells: 700.4;Retinal ganglion cells: 231.8;Rod photoreceptor cells: 775.4" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in single" 6 "Glioblastoma Multiforme (TCGA): 2.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 7.1;prostate cancer: 5.1" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Stomach - Gastric enteroendocrine cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052783 Uncertain NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 37: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 31 "HPA052783: " "unprognostic (9.11e-2)" "unprognostic (7.65e-2)" SRRM5 ENSG00000226763 "Serine/arginine repetitive matrix 5" B3KS81 19 43596617-43614498 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "testis: 45.0" "Cell type enhanced" "Detected in many" "Adipocytes: 22.3;Cardiomyocytes: 111.3;Early spermatids: 244.5;Epicardial cells: 38.7;Late spermatids: 84.2" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in some" 6 "Prostate Adenocarcinoma (TCGA): 4.5;Uterine Corpus Endometrial Carcinoma (TCGA): 12.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047399, HPA052924" Uncertain Approved Vesicles,Centrosome NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 15: Non-specific - Transcription" "Cluster 56: Non-specific - Sensory perception" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" Vesicles Centrosome "HPA047399: , HPA052924: " "unprognostic (4.60e-3)" "unprognostic (8.72e-2)" "unprognostic (4.10e-1)" "unprognostic (1.00e-1)" "unprognostic (1.58e-2)" "unprognostic (1.50e-2)" "potential prognostic favorable (1.68e-4)" "unprognostic (3.70e-2)" "unprognostic (2.41e-1)" "unprognostic (1.53e-1)" "unprognostic (1.84e-1)" SRRT "ARS2, Asr2, serrate" ENSG00000087087 "Serrate, RNA effector molecule" Q9BXP5 7 100875103-100888664 "Essential proteins, Predicted intracellular proteins" "RNA-mediated gene silencing, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 243.7;Late primary spermatocytes: 312.6;Late spermatids: 449.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042858, HPA058379" Supported Enhanced Nucleoplasm NA NA 9400 "Cluster 3: Non-specific - Nuclear processes" "Cluster 67: Testis - Mixed function" "Cluster 25: Non-specific - Transcription" "Cluster 39: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 56 Nucleoplasm "HPA042858: , HPA058379: " "unprognostic (4.76e-2)" "unprognostic (1.33e-1)" "unprognostic (1.40e-1)" "unprognostic (3.66e-1)" "unprognostic (3.71e-1)" "unprognostic (3.13e-1)" "unprognostic (1.83e-1)" "unprognostic (8.72e-2)" "unprognostic (5.75e-2)" "potential prognostic unfavorable (6.43e-5)" "unprognostic (9.59e-2)" "unprognostic (3.63e-1)" "unprognostic (3.15e-1)" "potential prognostic unfavorable (7.64e-7)" "unprognostic (3.11e-2)" "unprognostic (1.23e-1)" "unprognostic (4.45e-3)" "unprognostic (1.74e-2)" "unprognostic (6.14e-3)" "unprognostic (8.12e-2)" "unprognostic (2.72e-3)" "unprognostic (6.46e-3)" "unprognostic (2.88e-3)" "unprognostic (1.57e-2)" "unprognostic (3.67e-2)" "unprognostic (5.67e-2)" "unprognostic (4.72e-3)" "unprognostic (3.30e-2)" "unprognostic (2.52e-1)" "unprognostic (1.46e-1)" "unprognostic (5.83e-3)" SRSF1 "ASF, MGC5228, SF2, SF2p33, SFRS1, SRp30a" ENSG00000136450 "Serine and arginine rich splicing factor 1" Q07955 17 58000919-58007346 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, mRNA transport, Transport" RNA-binding "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 8.3;Epididymal principal cells: 7.5;Loop of henle epithelial cells: 8.6;Papillary tip epithelial cells: 5.1;Podocytes: 7.2;Proximal tubule cells: 7.5;Renal collecting duct intercalated cells: 12.0;Renal collecting duct principal cells: 6.1;Renal connecting tubule cells: 10.7" "Low cell type specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013073, HPA061301, HPA069970" Supported Approved Nucleoplasm,Cytosol NA NA 82000 "Cluster 13: Non-specific - Mitochondria" "Cluster 49: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 105: Non-specific - Mixed function" 222 Nucleoplasm Cytosol "CAB013073: , HPA061301: , HPA069970: " "unprognostic (2.87e-1)" "unprognostic (9.09e-3)" "unprognostic (4.68e-2)" "unprognostic (2.20e-2)" "unprognostic (1.83e-2)" "unprognostic (1.67e-1)" "unprognostic (1.80e-1)" "unprognostic (1.04e-1)" "potential prognostic unfavorable (7.36e-4)" "potential prognostic favorable (6.37e-4)" "unprognostic (4.41e-3)" "unprognostic (9.99e-2)" "validated prognostic unfavorable (2.10e-4)" "validated prognostic unfavorable (1.33e-4)" "unprognostic (2.53e-3)" "unprognostic (1.43e-2)" "unprognostic (1.08e-1)" "unprognostic (1.52e-2)" "unprognostic (2.06e-1)" "unprognostic (2.25e-1)" "unprognostic (3.75e-2)" "unprognostic (5.61e-3)" "unprognostic (9.20e-2)" "unprognostic (8.62e-3)" "unprognostic (4.74e-2)" "unprognostic (9.35e-2)" "unprognostic (3.26e-2)" "unprognostic (1.66e-1)" "unprognostic (3.62e-1)" "unprognostic (4.81e-2)" SRSF10 "FUSIP1, FUSIP2, PPP1R149, SFRS13, SFRS13A, SRp38, SRrp40, TASR1, TASR2" ENSG00000188529 "Serine and arginine rich splicing factor 10" O75494 1 23964347-23980927 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053805, HPA053831" Uncertain Supported Nucleoplasm NA Yes "Cluster 42: Non-specific - Vesicular transport" "Cluster 15: Bone marrow - Innate immune response" "Cluster 55: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 47 Nucleoplasm "HPA053805: , HPA053831: " "unprognostic (8.07e-2)" "unprognostic (3.01e-2)" "unprognostic (1.68e-2)" "unprognostic (1.09e-1)" "unprognostic (3.65e-2)" "unprognostic (3.44e-1)" "unprognostic (3.89e-2)" "unprognostic (4.48e-2)" "unprognostic (2.36e-2)" "potential prognostic favorable (2.49e-4)" "unprognostic (9.89e-3)" "unprognostic (5.19e-2)" "potential prognostic unfavorable (5.37e-5)" "unprognostic (1.52e-3)" "unprognostic (1.68e-3)" "unprognostic (5.33e-2)" "unprognostic (2.40e-2)" "unprognostic (1.83e-2)" "unprognostic (4.67e-1)" "unprognostic (3.11e-1)" "unprognostic (2.35e-2)" "unprognostic (7.95e-3)" "unprognostic (1.45e-3)" "unprognostic (1.79e-2)" "unprognostic (3.03e-1)" "unprognostic (5.80e-2)" "unprognostic (5.55e-2)" "unprognostic (2.73e-1)" "unprognostic (8.98e-2)" "unprognostic (6.48e-2)" SRSF11 "NET2, p54, SFRS11" ENSG00000116754 "Serine and arginine rich splicing factor 11" Q05519 1 70205682-70253052 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008762 Supported Supported "Nuclear speckles" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 64: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 37: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 41 "Nuclear speckles" "HPA008762: " "unprognostic (1.09e-2)" "unprognostic (2.27e-1)" "unprognostic (6.45e-2)" "unprognostic (6.68e-2)" "unprognostic (1.82e-2)" "unprognostic (1.01e-2)" "unprognostic (2.29e-2)" "unprognostic (1.91e-2)" "unprognostic (3.03e-2)" "unprognostic (6.63e-2)" "unprognostic (1.40e-1)" "unprognostic (2.94e-1)" "potential prognostic unfavorable (3.98e-5)" "unprognostic (1.10e-1)" "unprognostic (2.08e-1)" "unprognostic (1.29e-1)" "unprognostic (6.46e-2)" "unprognostic (1.25e-2)" "unprognostic (2.40e-1)" "unprognostic (1.70e-1)" "unprognostic (2.84e-1)" "unprognostic (9.79e-3)" "unprognostic (3.98e-2)" "unprognostic (3.39e-3)" "unprognostic (1.88e-1)" "unprognostic (8.18e-3)" "unprognostic (9.86e-2)" "unprognostic (9.29e-2)" "unprognostic (1.56e-1)" "unprognostic (3.12e-2)" SRSF12 "SFRS13B, SFRS19, SRrp35" ENSG00000154548 "Serine and arginine rich splicing factor 12" Q8WXF0 6 89095959-89118071 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 10.7" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 65.4;Early spermatids: 154.9;Epicardial cells: 307.0;Late primary spermatocytes: 188.4;Late spermatids: 332.3;Undifferentiated spermatogonia: 68.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 6.9" "Stomach - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049782 Approved NA NA "Cluster 67: Testis - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 7 "HPA049782: " "unprognostic (3.29e-1)" "unprognostic (2.08e-3)" "unprognostic (6.85e-2)" "unprognostic (8.16e-3)" "unprognostic (1.72e-1)" "unprognostic (1.47e-1)" "unprognostic (3.07e-2)" "unprognostic (1.40e-2)" "unprognostic (3.56e-1)" "unprognostic (3.43e-2)" "unprognostic (1.96e-1)" "unprognostic (4.63e-2)" "unprognostic (1.19e-1)" "unprognostic (1.57e-2)" SRSF2 "PR264, SC-35, SC35, SFRS2, SFRS2A" ENSG00000161547 "Serine and arginine rich splicing factor 2" Q01130 17 76734115-76737333 "Cancer-related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 680.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049905 Supported Approved Nucleoplasm,Cytosol NA NA 53000 "Cluster 13: Non-specific - Mitochondria" "Cluster 49: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 20: Non-specific - Transcription regulation" 34 Nucleoplasm Cytosol "HPA049905: " "unprognostic (1.19e-1)" "unprognostic (2.94e-1)" "unprognostic (7.54e-2)" "unprognostic (2.78e-2)" "unprognostic (7.99e-3)" "unprognostic (1.94e-1)" "unprognostic (6.03e-2)" "unprognostic (6.55e-2)" "unprognostic (1.03e-2)" "unprognostic (1.54e-1)" "unprognostic (1.13e-2)" "unprognostic (2.04e-2)" "validated prognostic unfavorable (1.96e-4)" "validated prognostic unfavorable (2.35e-4)" "unprognostic (1.36e-2)" "unprognostic (4.86e-2)" "unprognostic (2.07e-1)" "potential prognostic favorable (1.71e-4)" "unprognostic (8.81e-2)" "unprognostic (1.41e-2)" "unprognostic (1.97e-1)" "unprognostic (1.48e-2)" "unprognostic (1.05e-2)" "unprognostic (3.68e-3)" "unprognostic (4.67e-2)" "unprognostic (1.84e-1)" "unprognostic (3.92e-2)" "unprognostic (2.07e-1)" "unprognostic (7.07e-3)" "unprognostic (2.88e-1)" SRSF3 "SFRS3, SRp20" ENSG00000112081 "Serine and arginine rich splicing factor 3" P84103 6 36594353-36605600 "Cancer-related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, mRNA transport, Transport" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012986, HPA056981" Supported Supported Nucleoplasm NA NA 120000 "Cluster 13: Non-specific - Mitochondria" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 21: Non-specific - Metabolism" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 20: Non-specific - Transcription regulation" 82 Nucleoplasm "CAB012986: , HPA056981: " "unprognostic (1.51e-3)" "unprognostic (8.43e-2)" "unprognostic (3.87e-2)" "unprognostic (1.62e-3)" "unprognostic (9.52e-2)" "unprognostic (1.85e-1)" "unprognostic (1.71e-2)" "unprognostic (1.34e-1)" "unprognostic (4.61e-2)" "potential prognostic favorable (9.47e-8)" "unprognostic (1.42e-1)" "unprognostic (4.80e-2)" "potential prognostic unfavorable (1.35e-6)" "unprognostic (1.10e-3)" "unprognostic (1.73e-2)" "unprognostic (1.29e-2)" "unprognostic (6.27e-3)" "unprognostic (3.30e-3)" "unprognostic (7.83e-2)" "unprognostic (1.86e-1)" "unprognostic (1.12e-2)" "unprognostic (1.52e-2)" "unprognostic (2.51e-2)" "unprognostic (7.54e-2)" "unprognostic (2.07e-1)" "unprognostic (3.22e-2)" "unprognostic (1.19e-1)" "unprognostic (2.06e-1)" "unprognostic (1.18e-1)" "unprognostic (1.35e-1)" SRSF4 "SFRS4, SRP75" ENSG00000116350 "Serine and arginine rich splicing factor 4" Q08170 1 29147743-29181900 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050975 Supported Supported "Nuclear speckles" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 24: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 30 "Nuclear speckles" "HPA050975: " "potential prognostic favorable (1.79e-4)" "unprognostic (6.28e-2)" "unprognostic (2.76e-2)" "unprognostic (1.68e-1)" "unprognostic (1.08e-1)" "unprognostic (3.08e-1)" "unprognostic (5.93e-2)" "unprognostic (1.21e-1)" "unprognostic (7.61e-3)" "unprognostic (1.13e-1)" "unprognostic (7.83e-3)" "unprognostic (1.28e-2)" "potential prognostic unfavorable (1.76e-4)" "unprognostic (1.66e-1)" "unprognostic (1.40e-1)" "unprognostic (4.03e-2)" "unprognostic (2.12e-1)" "unprognostic (2.05e-1)" "unprognostic (6.00e-2)" "unprognostic (1.09e-2)" "unprognostic (1.01e-1)" "unprognostic (1.97e-1)" "potential prognostic unfavorable (2.75e-4)" "unprognostic (2.13e-1)" "unprognostic (1.06e-2)" "unprognostic (2.72e-2)" "unprognostic (2.00e-2)" "unprognostic (1.22e-1)" "unprognostic (5.90e-2)" "unprognostic (7.25e-3)" SRSF5 "HRS, SFRS5, SRP40" ENSG00000100650 "Serine and arginine rich splicing factor 5" Q13243 14 69726900-69772005 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 3025.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Peritubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043484, HPA056523" Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA 15000 "Cluster 33: Non-specific - ATP binding" "Cluster 15: Bone marrow - Innate immune response" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 84: Apical squamous epithelium - Cornification" 122 Nucleoplasm "Nucleoli, Cytosol" "HPA043484: , HPA056523: " "unprognostic (1.15e-2)" "unprognostic (4.95e-2)" "unprognostic (4.50e-3)" "unprognostic (1.31e-1)" "unprognostic (3.97e-2)" "unprognostic (2.20e-1)" "unprognostic (2.34e-2)" "unprognostic (1.52e-1)" "unprognostic (1.19e-1)" "validated prognostic favorable (2.20e-5)" "validated prognostic favorable (8.01e-4)" "unprognostic (3.09e-2)" "unprognostic (1.95e-1)" "unprognostic (5.37e-3)" "unprognostic (2.35e-1)" "unprognostic (9.03e-2)" "unprognostic (3.21e-1)" "unprognostic (2.25e-3)" "unprognostic (3.42e-2)" "unprognostic (4.05e-1)" "unprognostic (1.70e-1)" "unprognostic (7.95e-3)" "unprognostic (5.03e-2)" "unprognostic (5.48e-2)" "unprognostic (2.10e-1)" "unprognostic (5.01e-1)" "unprognostic (5.99e-2)" "unprognostic (1.77e-1)" "unprognostic (1.29e-1)" "unprognostic (2.75e-2)" SRSF6 "B52, SFRS6, SRP55" ENSG00000124193 "Serine and arginine rich splicing factor 6" Q13247 20 43457893-43466046 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 81.2;Bergmann glia: 89.6;Brain excitatory neurons: 51.2;Brain inhibitory neurons: 52.9;Choroid plexus epithelial cells: 81.2;Distal convoluted tubule cells: 49.8;Ependymal cells: 49.9;Loop of henle epithelial cells: 43.4;Microglia: 61.7;Oligodendrocyte progenitor cells: 130.2;Oligodendrocytes: 103.2;Other brain neurons: 51.0;Platelets: 42.2;Podocytes: 46.5;Proximal tubule cells: 57.6;Renal collecting duct intercalated cells: 52.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029005, CAB034889" Supported Supported "Nuclear speckles" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 15: Bone marrow - Innate immune response" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 62: Non-specific - Plasma proteins" "Cluster 98: Neurons - Neurotransmission & signaling" 77 "Nuclear speckles" "CAB034889: , HPA029005: " "unprognostic (1.52e-1)" "unprognostic (6.10e-2)" "unprognostic (2.63e-1)" "unprognostic (8.96e-2)" "unprognostic (3.96e-2)" "unprognostic (1.12e-1)" "unprognostic (1.57e-2)" "unprognostic (2.60e-1)" "unprognostic (1.33e-2)" "unprognostic (1.98e-1)" "unprognostic (1.11e-1)" "unprognostic (8.67e-2)" "unprognostic (2.37e-2)" "unprognostic (1.75e-1)" "unprognostic (1.90e-1)" "unprognostic (3.02e-1)" "unprognostic (1.53e-1)" "potential prognostic favorable (1.96e-4)" "unprognostic (5.71e-2)" "unprognostic (3.81e-2)" "unprognostic (1.09e-2)" "unprognostic (1.10e-3)" "unprognostic (1.38e-2)" "unprognostic (2.51e-2)" "unprognostic (8.10e-2)" "unprognostic (1.07e-2)" "unprognostic (1.32e-1)" "unprognostic (2.72e-2)" "unprognostic (6.58e-2)" "unprognostic (4.24e-1)" SRSF7 "9G8, AAG3, HSSG1, RBM37, SFRS7, ZCCHC20, ZCRB2" ENSG00000115875 "Serine and arginine rich splicing factor 7" Q16629 2 38743599-38751494 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, mRNA transport, Transport" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Breast lactating cells: 935.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043850, HPA056926" Supported Enhanced Nucleoplasm NA NA 58000 "Cluster 13: Non-specific - Mitochondria" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 21: Non-specific - Metabolism" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 20: Non-specific - Transcription regulation" 59 Nucleoplasm "HPA043850: , HPA056926: " "unprognostic (7.46e-2)" "unprognostic (5.80e-2)" "unprognostic (2.19e-1)" "unprognostic (2.14e-2)" "unprognostic (2.90e-2)" "unprognostic (3.60e-1)" "unprognostic (3.39e-2)" "unprognostic (5.70e-2)" "unprognostic (3.71e-3)" "potential prognostic favorable (3.43e-5)" "unprognostic (9.31e-2)" "unprognostic (5.81e-2)" "validated prognostic unfavorable (3.56e-5)" "validated prognostic unfavorable (4.85e-4)" "unprognostic (1.86e-3)" "unprognostic (4.49e-3)" "unprognostic (3.95e-1)" "unprognostic (1.15e-2)" "unprognostic (9.65e-2)" "unprognostic (1.24e-1)" "unprognostic (6.60e-3)" "potential prognostic unfavorable (4.17e-5)" "unprognostic (3.84e-2)" "unprognostic (9.18e-2)" "unprognostic (4.08e-2)" "unprognostic (6.76e-2)" "unprognostic (4.10e-2)" "unprognostic (1.68e-1)" "unprognostic (1.15e-1)" "unprognostic (3.63e-2)" SRSF8 "SFRS2B, SRP46" ENSG00000263465 "Serine and arginine rich splicing factor 8" Q9BRL6 11 95066919-95071225 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Platelets: 242.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" HPA049905 Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 33: Thyroid gland - Tissue development" "Cluster 31: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 15: Non-specific - Protein processing" 15 Nucleoplasm Cytosol "HPA049905: " "unprognostic (1.89e-3)" "unprognostic (4.13e-3)" "unprognostic (7.16e-2)" "unprognostic (4.11e-1)" "unprognostic (1.50e-2)" "unprognostic (1.21e-1)" "unprognostic (2.56e-1)" "unprognostic (3.33e-2)" "potential prognostic favorable (1.05e-9)" "unprognostic (4.29e-3)" "unprognostic (2.44e-3)" "unprognostic (2.63e-1)" "unprognostic (2.04e-2)" "unprognostic (2.26e-1)" "unprognostic (1.84e-1)" "unprognostic (2.45e-1)" "unprognostic (3.75e-1)" "unprognostic (1.78e-1)" "unprognostic (2.80e-1)" "unprognostic (1.35e-1)" "unprognostic (1.48e-2)" "unprognostic (5.79e-2)" "unprognostic (5.78e-2)" "unprognostic (1.88e-1)" "unprognostic (1.62e-1)" "unprognostic (5.94e-2)" "unprognostic (3.15e-2)" SRSF9 "SFRS9, SRp30c" ENSG00000111786 "Serine and arginine rich splicing factor 9" Q13242 12 120461672-120495946 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 485.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049849 Supported Supported Nucleoplasm,Nucleoli No No "Cluster 45: Eosinophils - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 8: Non-specific - Secretory pathway" 58 Nucleoplasm Nucleoli "HPA049849: " "unprognostic (1.42e-2)" "unprognostic (5.69e-2)" "unprognostic (2.03e-1)" "unprognostic (2.22e-1)" "unprognostic (1.32e-1)" "unprognostic (1.31e-1)" "potential prognostic favorable (7.21e-4)" "unprognostic (3.21e-3)" "unprognostic (2.32e-2)" "unprognostic (4.82e-3)" "unprognostic (8.71e-3)" "unprognostic (1.46e-1)" "validated prognostic unfavorable (4.00e-7)" "validated prognostic unfavorable (1.25e-5)" "unprognostic (1.14e-3)" "unprognostic (6.46e-3)" "unprognostic (1.07e-1)" "unprognostic (1.76e-2)" "unprognostic (1.86e-2)" "unprognostic (1.65e-2)" "unprognostic (1.35e-1)" "unprognostic (5.58e-2)" "unprognostic (5.14e-2)" "unprognostic (6.01e-2)" "unprognostic (1.43e-1)" "unprognostic (5.68e-2)" "unprognostic (5.13e-2)" "unprognostic (2.84e-1)" "unprognostic (1.74e-1)" "unprognostic (1.03e-3)" SRXN1 "C20orf139, dJ850E9.2, Npn3, SRX1, YKL086W" ENSG00000271303 "Sulfiredoxin 1" Q9BYN0 20 646615-653200 "Enzymes, Predicted intracellular proteins" "Antioxidant, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 5.0;Brain inhibitory neurons: 6.0;Foveolar cells: 7.5;Megakaryocytes: 6.2;Mucous neck cells: 3.1;Neutrophils: 3.5;Other brain neurons: 7.2;Parietal cells: 3.5" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Lung Squamous Cell Carcinoma (TCGA): 180.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 12.3" "Lineage enriched" "Detected in many" 5 "granulocytes: 12.3" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 19: Astrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 109: Neurons - Neuronal signaling" 1 "unprognostic (1.96e-1)" "potential prognostic unfavorable (2.75e-4)" "unprognostic (4.03e-1)" "unprognostic (6.54e-2)" "unprognostic (3.10e-1)" "unprognostic (3.84e-2)" "unprognostic (1.44e-3)" "unprognostic (6.15e-2)" "potential prognostic unfavorable (1.78e-4)" "unprognostic (5.34e-3)" "potential prognostic unfavorable (4.47e-4)" "unprognostic (2.40e-3)" "potential prognostic unfavorable (1.24e-5)" "potential prognostic unfavorable (6.06e-5)" "unprognostic (8.86e-3)" "unprognostic (2.81e-3)" "unprognostic (4.25e-2)" "unprognostic (1.24e-1)" "unprognostic (4.78e-2)" "unprognostic (1.01e-2)" "unprognostic (5.52e-2)" "unprognostic (8.07e-2)" "unprognostic (7.96e-2)" "unprognostic (1.90e-2)" "unprognostic (2.83e-1)" "unprognostic (3.00e-2)" "unprognostic (2.63e-1)" "unprognostic (2.23e-2)" "unprognostic (1.38e-1)" SRY TDF ENSG00000184895 "Sex determining region Y" Q05066 Y 2786855-2787682 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Sexual differentiation, Transcription, Transcription regulation" "Activator, Calmodulin-binding, DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skin 1: 1.6;testis: 2.3" "Group enriched" "Detected in some" 5 "Ependymal cells: 6.0;Sertoli cells: 10.9" "Group enriched" "Detected in some" 9 "choroid plexus epithelial cell: 3.9;ependymal cell: 7.6" "Cancer enhanced" "Detected in single" "Testicular Germ Cell Tumor (TCGA): 1.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 47: Testis - Mixed function" "Cluster 3: Choroid plexus - Cilium" "Cluster 18: Liver cancer - Metabolism" "Cluster 34: Ciliated cells - Cilia assembly & function" 4 "unprognostic (4.25e-1)" SS18 "SMARCL1, SSXT, SYT" ENSG00000141380 "SS18 subunit of BAF chromatin remodeling complex" Q15532 18 26016253-26091217 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Sertoli cells: 369.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055741, HPA059539" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 75: Ovary - Mixed function" "Cluster 55: Non-specific - Transcription" "Cluster 13: Non-specific - Mixed function" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 44 Nucleoplasm Cytosol "HPA055741: , HPA059539: " "unprognostic (1.30e-1)" "unprognostic (1.43e-1)" "unprognostic (9.72e-3)" "unprognostic (1.28e-1)" "unprognostic (2.08e-1)" "unprognostic (1.11e-2)" "unprognostic (1.40e-1)" "unprognostic (3.32e-2)" "unprognostic (1.06e-1)" "unprognostic (1.43e-1)" "unprognostic (1.85e-3)" "potential prognostic favorable (8.81e-4)" "unprognostic (6.87e-3)" "unprognostic (1.06e-1)" "unprognostic (4.82e-2)" "unprognostic (1.99e-1)" "unprognostic (1.87e-1)" "unprognostic (4.07e-2)" "unprognostic (8.79e-2)" "unprognostic (1.37e-1)" "unprognostic (1.78e-1)" "unprognostic (8.41e-2)" "unprognostic (3.37e-2)" "unprognostic (6.01e-2)" "unprognostic (2.95e-1)" "unprognostic (1.95e-1)" "unprognostic (2.21e-1)" "unprognostic (3.64e-2)" "unprognostic (1.70e-1)" "unprognostic (2.58e-1)" "unprognostic (3.35e-1)" SS18L1 "CREST, KIAA0693, SMARCL2" ENSG00000184402 "SS18L1 subunit of BAF chromatin remodeling complex" O75177 20 62143769-62182514 "Cancer-related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011827, HPA059046" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 64: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 23 "Nucleoplasm, Cytosol" "CAB011827: , HPA059046: " "unprognostic (3.44e-3)" "unprognostic (2.45e-2)" "unprognostic (3.73e-1)" "unprognostic (3.62e-2)" "unprognostic (8.16e-2)" "unprognostic (9.37e-2)" "unprognostic (1.72e-1)" "unprognostic (8.98e-3)" "unprognostic (3.12e-3)" "unprognostic (2.67e-3)" "unprognostic (6.01e-2)" "unprognostic (1.45e-1)" "unprognostic (1.68e-1)" "unprognostic (2.43e-1)" "unprognostic (2.29e-3)" "unprognostic (5.78e-3)" "unprognostic (8.54e-2)" "unprognostic (1.15e-1)" "unprognostic (4.45e-3)" "unprognostic (2.66e-2)" "unprognostic (3.72e-1)" "unprognostic (2.60e-3)" "potential prognostic unfavorable (5.28e-5)" "unprognostic (4.42e-2)" "potential prognostic favorable (9.47e-4)" "unprognostic (2.38e-3)" "unprognostic (2.90e-1)" "unprognostic (2.55e-1)" "unprognostic (1.97e-1)" "unprognostic (1.74e-1)" "unprognostic (2.72e-2)" SS18L2 KIAA-iso ENSG00000008324 "SS18 like 2" Q9UHA2 3 42581840-42596934 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047377 Approved Approved Nucleoplasm,Nucleoli,Mitochondria Yes No "Cluster 39: T-cells - T-cell receptor" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 100: Stratified epithelial cells - Barrier functions" 22 "Nucleoli, Mitochondria" Nucleoplasm "HPA047377: " "unprognostic (7.92e-2)" "unprognostic (6.98e-3)" "unprognostic (1.23e-2)" "unprognostic (2.36e-2)" "unprognostic (2.56e-1)" "unprognostic (5.78e-2)" "unprognostic (1.32e-1)" "unprognostic (2.07e-1)" "unprognostic (1.32e-1)" "potential prognostic unfavorable (1.12e-5)" "unprognostic (5.42e-3)" "unprognostic (3.29e-3)" "unprognostic (2.53e-2)" "validated prognostic unfavorable (4.76e-4)" "validated prognostic unfavorable (2.50e-6)" "unprognostic (4.91e-3)" "unprognostic (3.46e-2)" "unprognostic (5.15e-3)" "unprognostic (2.29e-1)" "unprognostic (1.75e-1)" "unprognostic (1.19e-1)" "unprognostic (9.37e-2)" "unprognostic (1.25e-1)" "unprognostic (7.54e-2)" "unprognostic (2.99e-2)" "unprognostic (4.90e-3)" "unprognostic (8.63e-2)" "unprognostic (7.36e-2)" "unprognostic (1.99e-1)" "unprognostic (1.28e-1)" "unprognostic (2.05e-1)" SSB "La, La/SSB, LARP3" ENSG00000138385 "Small RNA binding exonuclease protection factor La" P05455 2 169791933-169812064 "Essential proteins, Predicted intracellular proteins" RNA-binding "Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 483.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004643, HPA017287" Supported Approved Nucleoplasm NA NA 90000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 17: Non-specific - RNA processing" 229 Nucleoplasm "CAB004643: , HPA017287: " "unprognostic (1.97e-2)" "unprognostic (2.21e-2)" "unprognostic (6.62e-2)" "unprognostic (2.71e-1)" "unprognostic (1.88e-1)" "unprognostic (2.00e-2)" "unprognostic (1.37e-1)" "unprognostic (8.09e-2)" "unprognostic (1.43e-3)" "unprognostic (1.63e-2)" "unprognostic (1.15e-3)" "unprognostic (2.34e-1)" "potential prognostic unfavorable (9.44e-5)" "validated prognostic unfavorable (2.13e-7)" "validated prognostic unfavorable (1.19e-4)" "potential prognostic unfavorable (2.44e-4)" "unprognostic (3.02e-2)" "unprognostic (1.21e-1)" "unprognostic (4.22e-3)" "unprognostic (2.33e-1)" "unprognostic (1.42e-1)" "unprognostic (3.57e-2)" "unprognostic (3.14e-3)" "unprognostic (9.12e-2)" "unprognostic (2.54e-1)" "unprognostic (1.01e-1)" "unprognostic (9.65e-2)" "unprognostic (3.26e-1)" "unprognostic (3.45e-1)" "unprognostic (7.75e-2)" "unprognostic (1.61e-1)" SSBP1 "mtSSB, SSBP" ENSG00000106028 "Single stranded DNA binding protein 1" Q04837 7 141738334-141787922 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA replication" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal suprabasal cells: 526.0;Gastric progenitor cells: 492.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002866 Supported Supported "Mitochondria,Calyx,Principal piece" NA NA 36000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 73 Mitochondria "Calyx, Principal piece" "HPA002866: " "unprognostic (9.42e-3)" "unprognostic (2.70e-1)" "unprognostic (1.81e-2)" "unprognostic (2.22e-2)" "unprognostic (2.46e-1)" "unprognostic (6.50e-2)" "unprognostic (2.40e-3)" "unprognostic (2.40e-1)" "unprognostic (7.28e-3)" "potential prognostic unfavorable (2.47e-4)" "unprognostic (3.28e-3)" "unprognostic (2.45e-3)" "unprognostic (3.98e-1)" "validated prognostic unfavorable (3.70e-6)" "validated prognostic unfavorable (3.78e-5)" "potential prognostic unfavorable (5.04e-5)" "unprognostic (3.08e-3)" "unprognostic (1.03e-1)" "unprognostic (4.02e-1)" "unprognostic (1.21e-3)" "unprognostic (8.06e-2)" "potential prognostic unfavorable (6.73e-5)" "unprognostic (1.08e-1)" "unprognostic (2.71e-1)" "unprognostic (2.49e-1)" "unprognostic (2.53e-2)" "unprognostic (8.73e-2)" "unprognostic (2.13e-1)" "unprognostic (1.60e-1)" "unprognostic (2.26e-1)" "unprognostic (4.76e-2)" SSBP2 HSPC116 ENSG00000145687 "Single stranded DNA binding protein 2" P81877 5 81412804-81751797 "Predicted intracellular proteins, Predicted membrane proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hematopoietic stem cells: 1661.4;Pituicytes/FSCs: 1401.6;Thymocytes: 2186.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020834, HPA068605, HPA071780" Approved Enhanced Nucleoplasm NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 80: Thymus - Adaptive immune response" "Cluster 55: Non-specific - Transcription" "Cluster 6: Leukemia - Signal transduction" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 63 Nucleoplasm "CAB020834: , HPA068605: , HPA071780: " "unprognostic (1.26e-1)" "unprognostic (6.57e-3)" "potential prognostic unfavorable (6.92e-4)" "unprognostic (3.89e-3)" "unprognostic (1.21e-1)" "unprognostic (6.24e-2)" "unprognostic (6.11e-2)" "unprognostic (3.53e-3)" "unprognostic (5.73e-2)" "unprognostic (1.14e-1)" "unprognostic (8.84e-3)" "unprognostic (1.29e-1)" "unprognostic (2.08e-1)" "unprognostic (7.49e-3)" "unprognostic (1.20e-1)" "unprognostic (4.14e-2)" "unprognostic (1.66e-1)" "unprognostic (1.59e-1)" "unprognostic (3.11e-2)" "unprognostic (1.52e-2)" "unprognostic (6.80e-2)" "unprognostic (2.91e-3)" "unprognostic (7.90e-3)" "unprognostic (3.09e-1)" "potential prognostic unfavorable (3.41e-5)" "unprognostic (7.75e-2)" "unprognostic (1.95e-1)" "unprognostic (8.09e-3)" "unprognostic (1.72e-1)" "unprognostic (7.26e-2)" "unprognostic (6.23e-2)" SSBP3 "CSDP, FLJ10355, SSDP, SSDP1" ENSG00000157216 "Single stranded DNA binding protein 3" Q9BWW4 1 54225432-54413479 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071780 Approved Nucleoplasm NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 75: Ovary - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 29 Nucleoplasm "HPA071780: " "unprognostic (1.54e-2)" "unprognostic (2.06e-1)" "unprognostic (1.34e-1)" "unprognostic (6.01e-3)" "unprognostic (4.00e-3)" "unprognostic (1.02e-1)" "unprognostic (9.83e-2)" "unprognostic (1.15e-3)" "unprognostic (1.17e-1)" "unprognostic (2.53e-2)" "potential prognostic favorable (5.90e-4)" "unprognostic (1.86e-2)" "unprognostic (2.28e-1)" "unprognostic (2.32e-3)" "unprognostic (3.66e-2)" "unprognostic (6.50e-3)" "unprognostic (1.16e-1)" "unprognostic (2.32e-1)" "unprognostic (3.77e-1)" "unprognostic (9.02e-2)" "unprognostic (3.92e-2)" "unprognostic (1.99e-1)" "unprognostic (6.85e-3)" "unprognostic (5.19e-1)" "unprognostic (4.09e-1)" "unprognostic (2.32e-1)" "unprognostic (3.59e-2)" "unprognostic (2.74e-1)" "unprognostic (1.90e-1)" "unprognostic (5.45e-2)" "unprognostic (7.32e-2)" SSBP4 ENSG00000130511 "Single stranded DNA binding protein 4" Q9BWG4 19 18418864-18434562 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ependymal cells: 192.0;Epididymal efferent duct ciliated cells: 178.4;Fallopian tube ciliated cells: 280.4;Respiratory ciliated cells: 264.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071780 Approved Nucleoplasm NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 33: Neurons - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 34 Nucleoplasm "HPA071780: " "unprognostic (1.20e-2)" "unprognostic (4.43e-2)" "unprognostic (3.17e-1)" "unprognostic (1.75e-1)" "unprognostic (3.87e-1)" "unprognostic (2.52e-1)" "unprognostic (3.42e-1)" "unprognostic (4.08e-1)" "unprognostic (2.10e-2)" "unprognostic (2.06e-1)" "potential prognostic unfavorable (2.19e-6)" "unprognostic (4.90e-2)" "unprognostic (3.96e-2)" "unprognostic (1.32e-2)" "unprognostic (3.71e-1)" "unprognostic (4.77e-3)" "unprognostic (9.13e-2)" "unprognostic (2.19e-1)" "unprognostic (1.37e-2)" "unprognostic (2.03e-1)" "unprognostic (1.05e-2)" "potential prognostic favorable (3.04e-5)" "unprognostic (2.00e-1)" "unprognostic (4.95e-2)" "unprognostic (1.56e-1)" "potential prognostic favorable (2.37e-5)" "unprognostic (5.16e-2)" "unprognostic (2.16e-2)" "unprognostic (2.66e-1)" "unprognostic (2.46e-1)" "unprognostic (1.53e-1)" SSC4D "S4D-SRCRB, SRCRB-S4D, SRCRB4D" ENSG00000146700 "Scavenger receptor cysteine rich family member with 4 domains" Q8WTU2 7 76389334-76409697 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 2.5;parathyroid gland: 6.6;pituitary gland: 2.4" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 38.9;Gonadotrophs: 34.8;Loop of henle epithelial cells: 21.0;Renal collecting duct principal cells: 24.3;Renal connecting tubule cells: 40.4;Retinal ganglion cells: 19.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 9.9" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Pituitary gland - Gonadotropes" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA062611 Uncertain "Secreted - unknown location" "No annotated function" NA NA 620000 "Cluster 69: Parathyroid gland - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 8 "HPA062611: " "unprognostic (3.70e-2)" "unprognostic (1.49e-1)" "potential prognostic unfavorable (4.59e-4)" "unprognostic (1.66e-1)" "potential prognostic unfavorable (3.04e-5)" "unprognostic (6.01e-2)" "unprognostic (1.48e-2)" "unprognostic (1.83e-1)" "unprognostic (1.11e-1)" "unprognostic (1.87e-1)" "unprognostic (1.57e-2)" "unprognostic (1.80e-2)" SSC5D "FLJ35258, S5D-SRCRB" ENSG00000179954 "Scavenger receptor cysteine rich family member with 5 domains" A1L4H1 19 55488404-55519099 "Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Corticotrophs: 77.3;Decidual stromal cells: 34.1;Endometrial stromal cells: 24.5;Fibro-adipogenic progenitors: 43.6;Fibroblasts: 30.0;Hepatic stellate cells: 51.6;Lactotrophs: 31.3;Leydig cells: 25.8;Myosatellite cells: 20.8;Peritubular myoid cells: 22.4;Schwann cells: 23.4;Smooth muscle cells: 28.4" "Cell type enhanced" "Detected in many" "fibroblast: 40.1;pericyte: 23.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 13.1" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Adrenal gland - Fibroblasts, Breast - Fibroblasts, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Minor Salivary Gland - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblasts_1, Spleen - Fibroblasts_2, Stomach - Fibroblasts, Testis - Peritubular cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA042008, HPA053316" Approved Approved Nucleoplasm,Cytosol "Secreted in other tissues" Receptor Yes NA 48000000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 6: Non-specific - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 15 "Nucleoplasm, Cytosol" "HPA042008: , HPA053316: " "unprognostic (6.76e-3)" "unprognostic (1.22e-1)" "unprognostic (3.51e-2)" "unprognostic (9.69e-2)" "unprognostic (1.29e-2)" "unprognostic (3.42e-1)" "unprognostic (7.94e-2)" "unprognostic (5.31e-2)" "unprognostic (3.59e-3)" "potential prognostic unfavorable (8.93e-4)" "unprognostic (1.92e-3)" "unprognostic (1.51e-1)" "unprognostic (2.42e-3)" "unprognostic (2.19e-1)" "unprognostic (7.29e-2)" "unprognostic (4.54e-2)" "unprognostic (6.05e-2)" "potential prognostic unfavorable (8.08e-4)" "unprognostic (2.28e-2)" "unprognostic (6.43e-2)" "unprognostic (8.10e-2)" "unprognostic (1.89e-2)" "unprognostic (3.34e-2)" "unprognostic (7.12e-2)" "unprognostic (6.64e-2)" "unprognostic (2.42e-2)" "unprognostic (1.44e-1)" "unprognostic (1.44e-3)" "unprognostic (4.44e-3)" SSH1 "KIAA1298, SSH1L" ENSG00000084112 "Slingshot protein phosphatase 1" Q8WYL5 12 108778191-108857590 "Enzymes, Predicted intracellular proteins" "Actin-binding, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Lymphatic endothelial cells: 291.5;Microglia: 234.5;Neutrophils: 352.9;Vascular endothelial cells: 276.9" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 291.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019845 Uncertain Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 69: Skin cancer - ECM organization" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 22 "Plasma membrane" "Nucleoplasm, Cytosol" "HPA019845: " "unprognostic (2.60e-3)" "unprognostic (7.30e-3)" "unprognostic (4.71e-2)" "unprognostic (2.69e-2)" "unprognostic (8.49e-2)" "unprognostic (5.10e-2)" "unprognostic (2.56e-2)" "unprognostic (2.68e-1)" "unprognostic (1.27e-1)" "unprognostic (4.07e-2)" "unprognostic (2.86e-2)" "unprognostic (1.56e-2)" "unprognostic (5.37e-1)" "potential prognostic unfavorable (2.34e-5)" "unprognostic (2.72e-1)" "unprognostic (8.60e-2)" "unprognostic (3.34e-3)" "unprognostic (4.61e-3)" "unprognostic (2.68e-1)" "unprognostic (1.75e-3)" "unprognostic (3.93e-3)" "unprognostic (4.17e-2)" "unprognostic (1.59e-3)" "unprognostic (4.92e-2)" "unprognostic (2.55e-1)" "unprognostic (1.17e-2)" "unprognostic (2.47e-1)" "unprognostic (2.50e-1)" "unprognostic (5.58e-1)" "unprognostic (9.86e-2)" "unprognostic (3.62e-1)" SSH2 KIAA1725 ENSG00000141298 "Slingshot protein phosphatase 2" Q76I76 17 29625938-29930276 "Enzymes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Actin-binding, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 92.5" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 1867.7;Neutrophils: 5621.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 135.2" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Macrophages, Spleen - Neutrophils_2, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017189, HPA057099" Uncertain NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 24: Neutrophils - Innate immunity signal integration" 7 "CAB017189: , HPA057099: " "unprognostic (2.30e-1)" "unprognostic (3.43e-1)" "unprognostic (2.88e-1)" "unprognostic (1.34e-2)" "unprognostic (2.76e-1)" "unprognostic (3.09e-1)" "unprognostic (9.29e-2)" "unprognostic (1.42e-2)" "unprognostic (2.75e-2)" "potential prognostic unfavorable (6.68e-5)" "potential prognostic favorable (1.53e-4)" "unprognostic (9.46e-2)" "unprognostic (2.54e-2)" "unprognostic (1.05e-2)" "unprognostic (6.71e-2)" "unprognostic (1.23e-2)" "unprognostic (1.48e-2)" "unprognostic (1.02e-1)" "unprognostic (6.21e-3)" "unprognostic (4.57e-2)" "unprognostic (2.67e-1)" "unprognostic (5.80e-2)" "unprognostic (4.23e-2)" "unprognostic (3.23e-1)" "unprognostic (8.26e-2)" "potential prognostic favorable (1.79e-4)" "unprognostic (1.21e-1)" "unprognostic (9.40e-2)" "unprognostic (8.19e-2)" "unprognostic (2.91e-2)" "unprognostic (7.19e-2)" SSH3 "FLJ10928, FLJ20515" ENSG00000172830 "Slingshot protein phosphatase 3" Q8TE77 11 67303478-67312607 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 97.3;Esophageal apical cells: 84.3;Esophageal suprabasal cells: 59.0;Prostatic club cells: 58.0;Prostatic hillock cells: 76.4;Urothelial cells: 74.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 11.6;eosinophil: 11.2" "Lineage enriched" "Detected in many" 5 "granulocytes: 11.6" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019949, HPA019957" Approved Approved "Nuclear speckles,Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 74: Non-specific - Signal transduction" "Cluster 30: White matter - Myelination" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 69: Urothelial cells - Basic cellular functions" 3 "Nuclear speckles, Cytosol" "Plasma membrane, Actin filaments" "HPA019949: , HPA019957: " "unprognostic (8.14e-2)" "unprognostic (8.01e-2)" "unprognostic (3.33e-1)" "unprognostic (1.93e-2)" "unprognostic (2.23e-2)" "unprognostic (1.86e-1)" "unprognostic (2.41e-2)" "potential prognostic unfavorable (8.73e-7)" "unprognostic (5.04e-2)" "unprognostic (4.87e-2)" "unprognostic (6.71e-2)" "unprognostic (5.87e-3)" "unprognostic (6.86e-2)" "unprognostic (3.85e-1)" "unprognostic (3.77e-1)" "unprognostic (7.47e-2)" "unprognostic (2.85e-3)" "unprognostic (1.55e-2)" "unprognostic (1.69e-2)" "unprognostic (1.66e-2)" "unprognostic (6.29e-2)" "potential prognostic unfavorable (2.27e-4)" "unprognostic (6.32e-3)" "unprognostic (2.69e-1)" "unprognostic (2.70e-2)" "unprognostic (1.20e-1)" "unprognostic (2.27e-2)" "unprognostic (3.76e-1)" "unprognostic (8.20e-2)" "unprognostic (1.09e-1)" "unprognostic (1.20e-1)" SSMEM1 "C7orf45, FLJ40316" ENSG00000165120 "Serine rich single-pass membrane protein 1" Q8WWF3 7 130206344-130216844 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 158 "testis: 30.2" "Group enriched" "Detected in some" 10 "Early spermatids: 471.7;Late primary spermatocytes: 453.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 92 SSNA1 "N14, NA14" ENSG00000176101 "SS nuclear autoantigen 1" O43805 9 137188660-137190370 "Predicted intracellular proteins" "Cell cycle, Cell division, Neurogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 471.7;Esophageal basal cells: 293.1;Esophageal suprabasal cells: 357.9;Late primary spermatocytes: 426.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074006 Approved "Nucleoplasm,Vesicles,Basal body,Cytosol" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 97: Non-specific - Cellular respiration" 19 "Nucleoplasm, Basal body" "Vesicles, Cytosol" "HPA074006: " "unprognostic (2.77e-2)" "unprognostic (2.49e-2)" "unprognostic (9.31e-3)" "unprognostic (6.95e-2)" "unprognostic (1.20e-2)" "unprognostic (3.42e-3)" "unprognostic (6.97e-2)" "unprognostic (1.46e-1)" "unprognostic (1.80e-2)" "unprognostic (1.32e-2)" "unprognostic (2.50e-2)" "unprognostic (8.54e-2)" "unprognostic (2.99e-2)" "potential prognostic unfavorable (8.51e-4)" "unprognostic (4.35e-3)" "unprognostic (9.59e-2)" "unprognostic (1.21e-1)" "unprognostic (3.44e-2)" "unprognostic (1.67e-1)" "unprognostic (1.84e-1)" "unprognostic (1.16e-1)" "unprognostic (2.71e-1)" "unprognostic (2.02e-1)" "unprognostic (3.04e-1)" "unprognostic (2.09e-2)" "unprognostic (2.79e-1)" "unprognostic (1.30e-1)" "unprognostic (1.04e-1)" "unprognostic (2.04e-2)" "unprognostic (6.13e-2)" "unprognostic (6.53e-2)" SSPN "KRAG, SPN1, SPN2" ENSG00000123096 Sarcospan Q14714 12 26121991-26299290 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 73.7" "Cell type enhanced" "Detected in many" "B-cells: 152.0;Breast myoepithelial cells: 196.3;Epicardial cells: 163.7;Leydig cells: 139.7;Peritubular myoid cells: 248.5;Plasma cells: 132.0;Smooth muscle cells: 165.4;Thymic myoid cells: 296.4" "Cell type enhanced" "Detected in all" "astrocyte: 122.1;ependymal cell: 139.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "memory B-cell: 57.7;naive B-cell: 17.1" "Lineage enriched" "Detected in many" 19 "B-cells: 57.7" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Minor Salivary Gland - Fibroblasts, Prostate - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066432 Approved "Nucleoplasm,Nuclear membrane" No No "Cluster 17: B-cells - Immunoglobulins" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 39: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 94: Gonadal somatic cells - Mixed function" "Nuclear membrane" Nucleoplasm "HPA066432: " "potential prognostic favorable (2.81e-5)" "unprognostic (5.25e-3)" "unprognostic (1.79e-1)" "unprognostic (7.97e-2)" "unprognostic (1.32e-1)" "unprognostic (1.15e-1)" "unprognostic (5.49e-1)" "potential prognostic unfavorable (3.61e-5)" "unprognostic (4.97e-2)" "unprognostic (1.43e-1)" "validated prognostic favorable (7.84e-4)" "validated prognostic favorable (4.98e-6)" "unprognostic (5.07e-2)" "unprognostic (9.92e-2)" "unprognostic (5.26e-2)" "unprognostic (4.59e-2)" "unprognostic (6.37e-3)" "unprognostic (3.69e-3)" "unprognostic (6.19e-2)" "unprognostic (1.64e-1)" "unprognostic (7.23e-3)" "unprognostic (1.31e-2)" "unprognostic (1.21e-1)" "unprognostic (8.03e-2)" "unprognostic (2.40e-2)" "unprognostic (2.50e-1)" "unprognostic (1.41e-3)" "unprognostic (3.93e-2)" "unprognostic (1.11e-1)" "unprognostic (6.26e-2)" SSR1 TRAPA ENSG00000124783 "Signal sequence receptor subunit 1" P43307 6 7268306-7347446 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011276, HPA017062" Enhanced Supported "Endoplasmic reticulum" NA NA 4500000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 22: Epididymis - Mixed function" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 63: Non-specific - Protein processing" "Cluster 8: Non-specific - Secretory pathway" 64 "Endoplasmic reticulum" "HPA011276: , HPA017062: " "unprognostic (1.51e-3)" "unprognostic (1.43e-1)" "unprognostic (2.63e-1)" "unprognostic (8.04e-3)" "unprognostic (2.50e-3)" "unprognostic (3.01e-2)" "unprognostic (1.15e-1)" "unprognostic (6.55e-3)" "unprognostic (1.70e-1)" "potential prognostic unfavorable (5.12e-4)" "potential prognostic favorable (1.09e-4)" "unprognostic (2.21e-2)" "unprognostic (2.87e-2)" "potential prognostic unfavorable (3.74e-4)" "unprognostic (2.03e-2)" "unprognostic (1.93e-1)" "unprognostic (2.38e-1)" "unprognostic (1.65e-2)" "unprognostic (2.65e-1)" "unprognostic (3.06e-2)" "unprognostic (1.29e-2)" "unprognostic (2.58e-2)" "unprognostic (1.54e-1)" "unprognostic (1.39e-1)" "unprognostic (1.43e-1)" "unprognostic (2.49e-1)" "unprognostic (7.40e-2)" "unprognostic (1.78e-1)" "unprognostic (2.88e-1)" "unprognostic (5.39e-3)" "unprognostic (4.70e-1)" SSR2 "TLAP, TRAPB" ENSG00000163479 "Signal sequence receptor subunit 2" P43308 1 156009048-156020951 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Decidual stromal cells: 822.3;Epididymal principal cells: 695.6;Extravillous trophoblasts: 1020.9;Plasma cells: 657.6;Syncytiotrophoblasts: 678.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Breast glandular cells, Pituitary gland - Somatotropes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 70: Non-specific - Protein processing" "Cluster 12: Non-specific - Vasculature" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 8: Non-specific - Secretory pathway" 3 "unprognostic (1.98e-1)" "unprognostic (2.12e-1)" "unprognostic (4.49e-2)" "unprognostic (7.79e-3)" "unprognostic (4.52e-1)" "unprognostic (1.34e-1)" "unprognostic (2.95e-1)" "unprognostic (1.49e-1)" "unprognostic (3.49e-2)" "unprognostic (2.71e-2)" "unprognostic (1.28e-1)" "unprognostic (2.18e-1)" "potential prognostic unfavorable (1.44e-4)" "potential prognostic unfavorable (1.01e-4)" "unprognostic (4.75e-3)" "unprognostic (2.35e-1)" "unprognostic (2.54e-2)" "unprognostic (3.26e-1)" "unprognostic (8.97e-2)" "unprognostic (1.89e-1)" "unprognostic (7.20e-2)" "unprognostic (8.24e-2)" "unprognostic (1.11e-1)" "unprognostic (4.52e-3)" "unprognostic (1.80e-1)" "unprognostic (4.97e-2)" "unprognostic (9.96e-2)" "unprognostic (1.76e-1)" "unprognostic (5.97e-2)" "unprognostic (8.74e-2)" "unprognostic (3.65e-1)" SSR3 TRAPG ENSG00000114850 "Signal sequence receptor subunit 3" Q9UNL2 3 156539553-156555149 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 586.5;Epididymal efferent duct absorptive cells: 697.1;Epididymal principal cells: 581.9;Extravillous trophoblasts: 635.8;Gastric progenitor cells: 603.7;Pancreatic acinar cells: 555.9;Plasma cells: 1030.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014906 Approved NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 8: Non-specific - Secretory pathway" 34 "HPA014906: " "unprognostic (3.92e-3)" "unprognostic (3.24e-2)" "unprognostic (4.12e-2)" "potential prognostic unfavorable (3.48e-4)" "unprognostic (2.60e-1)" "unprognostic (6.76e-2)" "unprognostic (8.34e-3)" "potential prognostic unfavorable (9.18e-5)" "potential prognostic unfavorable (4.23e-4)" "potential prognostic unfavorable (4.25e-4)" "unprognostic (2.53e-2)" "unprognostic (1.46e-3)" "unprognostic (6.06e-3)" "validated prognostic unfavorable (5.84e-5)" "validated prognostic unfavorable (1.13e-4)" "potential prognostic unfavorable (3.26e-4)" "unprognostic (5.55e-3)" "unprognostic (2.81e-1)" "unprognostic (9.39e-2)" "unprognostic (3.11e-1)" "unprognostic (4.12e-3)" "potential prognostic unfavorable (3.03e-4)" "unprognostic (4.32e-2)" "unprognostic (2.89e-1)" "unprognostic (2.21e-1)" "unprognostic (2.03e-1)" "unprognostic (1.28e-2)" "unprognostic (4.08e-1)" "unprognostic (5.59e-2)" "unprognostic (6.99e-2)" "unprognostic (6.72e-2)" SSR4 TRAPD ENSG00000180879 "Signal sequence receptor subunit 4" P51571 X 153793516-153798499 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Congenital disorder of glycosylation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 2940.4" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 2738.7;Gastric chief cells: 2476.8;Late spermatids: 2866.6;Pancreatic acinar cells: 1814.2;Plasma cells: 6648.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Spleen - Plasma cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045209 Enhanced Supported "Endoplasmic reticulum" NA NA 130000 "Cluster 13: Non-specific - Mitochondria" "Cluster 8: Pancreas - Proteolysis" "Cluster 21: Non-specific - Metabolism" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 67: Plasma cells - Plasma cell differentiation" 50 "Endoplasmic reticulum" "HPA045209: " "unprognostic (1.56e-3)" "unprognostic (2.58e-1)" "unprognostic (7.86e-3)" "unprognostic (5.33e-3)" "unprognostic (2.38e-2)" "unprognostic (5.81e-2)" "unprognostic (4.67e-2)" "unprognostic (1.11e-1)" "unprognostic (7.39e-2)" "unprognostic (1.19e-2)" "unprognostic (6.52e-3)" "potential prognostic unfavorable (5.84e-6)" "unprognostic (1.27e-3)" "unprognostic (1.25e-1)" "unprognostic (1.98e-2)" "unprognostic (9.65e-3)" "unprognostic (6.55e-2)" "unprognostic (5.50e-2)" "unprognostic (1.75e-1)" "unprognostic (1.45e-2)" "potential prognostic favorable (6.28e-4)" "unprognostic (8.58e-3)" "unprognostic (6.77e-2)" "unprognostic (2.08e-1)" "unprognostic (1.03e-1)" "unprognostic (1.68e-1)" "unprognostic (1.92e-1)" "unprognostic (8.48e-2)" "unprognostic (2.26e-1)" "unprognostic (2.70e-1)" "unprognostic (6.75e-2)" SSRP1 FACT80 ENSG00000149136 "Structure specific recognition protein 1" Q08945 11 57325986-57335892 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Transcription factors" "DNA damage, DNA repair, DNA replication, Host-virus interaction, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 186.8;Late spermatids: 212.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002696, HPA002697" Approved Supported Nucleoplasm,Nucleoli,Centrosome NA NA 25000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 24: Non-specific - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 538 Nucleoplasm "Nucleoli, Centrosome" "HPA002696: , HPA002697: " "unprognostic (3.97e-1)" "unprognostic (2.46e-1)" "unprognostic (3.99e-2)" "unprognostic (6.89e-3)" "unprognostic (3.82e-1)" "unprognostic (2.92e-1)" "unprognostic (1.20e-1)" "unprognostic (4.21e-2)" "unprognostic (4.62e-2)" "unprognostic (2.49e-2)" "potential prognostic favorable (8.80e-5)" "unprognostic (3.72e-2)" "unprognostic (6.23e-2)" "validated prognostic unfavorable (5.04e-7)" "validated prognostic unfavorable (8.30e-5)" "validated prognostic unfavorable (6.16e-4)" "validated prognostic unfavorable (8.42e-5)" "unprognostic (2.25e-1)" "unprognostic (1.77e-1)" "unprognostic (4.92e-2)" "unprognostic (1.11e-1)" "potential prognostic unfavorable (3.82e-4)" "unprognostic (2.08e-1)" "unprognostic (1.06e-1)" "unprognostic (5.79e-2)" "unprognostic (2.53e-1)" "unprognostic (1.12e-1)" "unprognostic (9.80e-2)" "unprognostic (1.95e-1)" "unprognostic (9.53e-2)" "unprognostic (4.36e-2)" SST "SMST, SST1" ENSG00000157005 Somatostatin P61278 3 187668912-187670394 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" Hormone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 12 "brain: 622.0;intestine: 363.7;pancreas: 479.7;stomach 1: 416.6" "Group enriched" "Detected in some" 42 "Neuroendocrine cells: 3600.0;Pancreatic islet cells: 8515.8" "Group enriched" "Detected in all" 8 "MGE interneuron: 666.5;splatter: 546.4" "Cancer enriched" "Detected in many" 4 "Pancreatic Adenocarcinoma (TCGA): 1707.0" "Region enhanced" "Detected in all" "hypothalamus: 999.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 8 "Neuroblastoma: 145.1;thyroid cancer: 489.5" "Adrenal gland - Adrenal medulla cells, Pancreas - Alpha cells, Pancreas - Beta cells, Skin - Inner root sheath cells, Stomach - Gastric enteroendocrine cells, Thyroid gland - Parafollicular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000075, HPA019472, CAB034105" Enhanced Supported "Secreted to blood" Hormone NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 1 "CAB000075: , CAB034105: , HPA019472: " "unprognostic (4.47e-1)" "unprognostic (2.60e-1)" "unprognostic (2.52e-1)" "unprognostic (1.52e-1)" "unprognostic (2.25e-2)" "unprognostic (4.48e-1)" "potential prognostic favorable (2.22e-4)" "potential prognostic favorable (1.56e-4)" "unprognostic (5.58e-3)" "unprognostic (1.22e-1)" "unprognostic (1.50e-1)" "unprognostic (1.09e-1)" "unprognostic (3.93e-1)" "unprognostic (1.86e-2)" "unprognostic (2.73e-2)" "unprognostic (8.12e-3)" "unprognostic (7.54e-2)" "unprognostic (2.21e-1)" "unprognostic (5.11e-1)" "unprognostic (6.31e-2)" "unprognostic (7.32e-2)" "unprognostic (2.65e-1)" "unprognostic (3.44e-1)" "potential prognostic unfavorable (3.31e-4)" SSTR1 ENSG00000139874 "Somatostatin receptor 1" P30872 14 38207904-38213067 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.8;intestine: 13.0;stomach 1: 20.5" "Cell type enhanced" "Detected in some" "Enterocytes: 13.9;Foveolar cells: 73.7;Gastric chief cells: 15.3;Mucous neck cells: 9.7;Neuroendocrine cells: 19.6;Oligodendrocyte progenitor cells: 25.1;Other brain neurons: 10.9;Pancreatic islet cells: 24.5;Parietal cells: 67.2" "Cell type enhanced" "Detected in many" "oligodendrocyte precursor cell: 21.5" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 7.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Fibroblasts, Pituitary gland - Lactotropes, Skin - Inner root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA003207, HPA031506" Approved Uncertain Vesicles NA NA "Cluster 77: Intestine - Digestion" "Cluster 24: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 9 Vesicles "HPA003207: , HPA031506: " "unprognostic (2.81e-1)" "unprognostic (3.20e-1)" "unprognostic (6.45e-3)" "potential prognostic favorable (5.52e-6)" "unprognostic (1.55e-1)" "potential prognostic favorable (2.62e-9)" "unprognostic (5.47e-3)" "unprognostic (5.44e-1)" "unprognostic (1.33e-2)" "unprognostic (3.56e-1)" "unprognostic (1.30e-1)" "unprognostic (1.60e-3)" "unprognostic (4.21e-3)" "unprognostic (1.16e-2)" "unprognostic (1.22e-1)" "unprognostic (3.69e-2)" "unprognostic (1.62e-3)" "unprognostic (2.99e-1)" SSTR2 ENSG00000180616 "Somatostatin receptor 2" P30874 17 73165010-73176633 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.7" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 1.5;Early spermatids: 1.7;Fibroblasts: 2.6;Late spermatids: 2.3;Loop of henle epithelial cells: 2.7;Neuroendocrine cells: 3.5;Papillary tip epithelial cells: 5.3;Pericytes: 3.2;Proximal tubule cells: 12.2;Renal collecting duct principal cells: 4.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.2" "Cancer enhanced" "Detected in some" "Neuroblastoma: 18.2" "Breast - Endothelial cells, Pituitary gland - Thyrotropes, Prostate - Fibroblasts, Stomach - Chief cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA007264 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 14: Neurons - Synaptic function" "Cluster 1: Neuronal - Visual perception" "Cluster 105: Non-specific - Mixed function" 7 Cytosol Nucleoplasm "HPA007264: " "unprognostic (2.27e-2)" "unprognostic (3.17e-2)" "unprognostic (1.36e-1)" "unprognostic (1.54e-2)" "unprognostic (8.31e-2)" "unprognostic (3.66e-2)" "potential prognostic favorable (4.25e-5)" "unprognostic (1.06e-2)" "unprognostic (2.45e-1)" "potential prognostic favorable (4.22e-7)" "unprognostic (8.38e-2)" "unprognostic (8.71e-3)" "unprognostic (1.25e-1)" "unprognostic (8.47e-2)" "unprognostic (1.15e-1)" "unprognostic (6.04e-2)" "unprognostic (4.43e-3)" "unprognostic (3.89e-1)" "potential prognostic favorable (1.02e-4)" "unprognostic (9.48e-2)" "unprognostic (2.46e-1)" "unprognostic (8.81e-2)" SSTR3 ENSG00000278195 "Somatostatin receptor 3" P32745 22 37204237-37212477 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.5;lymphoid tissue: 10.3;testis: 7.5" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 2.9;Gonadotrophs: 8.7;Granulosa cells: 6.5;Late spermatids: 1.7;Other brain neurons: 4.1;Pancreatic islet cells: 16.1;Plasma cells: 1.8;Sertoli cells: 6.0" "Cell type enhanced" "Detected in many" "thalamic excitatory: 9.3" "Cancer enhanced" "Detected in single" "Pancreatic Adenocarcinoma (TCGA): 2.8" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "naive CD4 T-cell: 1.1" "Lineage enriched" "Detected in single" 10 "T-cells: 1.1" "Cancer enriched" "Detected in some" 5 "Myeloma: 23.4" "Adipose visceral - Mesothelial cells, Kidney - Podocytes, Minor Salivary Gland - Plasma cells, Pancreas - Alpha cells, Pancreas - Beta cells, Pituitary gland - Gonadotropes, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022647 Approved Approved "Plasma membrane,Actin filaments,Primary cilium" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 5 "Plasma membrane, Actin filaments, Primary cilium" "CAB022647: " "unprognostic (1.89e-3)" SSTR4 ENSG00000132671 "Somatostatin receptor 4" P31391 20 23035312-23039237 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Early spermatids: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enteroendocrine cells, Skin - Inner root sheath cells" "Low region specificity" "Detected in many" HPA064252 Uncertain NA NA "Cluster 51: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 1 "HPA064252: " SSTR5 ENSG00000162009 "Somatostatin receptor 5" P35346 16 1072747-1081454 "FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 2.1;blood vessel: 2.6;heart muscle: 2.4;kidney: 3.9;pituitary gland: 2.1" "Group enriched" "Detected in some" 4 "Neuroendocrine cells: 15.8;Retinal horizontal cells: 48.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "hypothalamus: 2.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 5.6" "Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Pancreas - Beta cells, Prostate - Prostate basal glandular cells" "Group enriched" "Detected in some" 5 "basal ganglia: 4.1;hypothalamus: 2.3" "Low region specificity" "Detected in many" HPA066503 Supported "Plasma membrane" NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" 4 "Plasma membrane" "HPA066503: " "unprognostic (2.15e-2)" "unprognostic (2.14e-1)" "unprognostic (5.25e-2)" "unprognostic (4.57e-2)" "unprognostic (2.19e-1)" "unprognostic (3.40e-1)" "unprognostic (9.68e-2)" "unprognostic (4.65e-2)" "unprognostic (2.12e-1)" "unprognostic (3.16e-1)" SSU72 HSPC182 ENSG00000160075 "SSU72 homolog, RNA polymerase II CTD phosphatase" Q9NP77 1 1541673-1574863 "Enzymes, Essential proteins, Predicted intracellular proteins" "mRNA processing" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 821.9;Esophageal suprabasal cells: 443.1;Late spermatids: 1130.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous)" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA069290, HPA070604" Supported Approved Nucleoplasm,Cytosol No No "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 1: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 85: Squamous epithelial cells - Keratinization" 11 "Nucleoplasm, Cytosol" "HPA069290: , HPA070604: " "unprognostic (4.36e-1)" "unprognostic (1.61e-1)" "unprognostic (4.65e-2)" "unprognostic (3.58e-1)" "unprognostic (2.07e-1)" "unprognostic (2.21e-1)" "unprognostic (1.08e-1)" "unprognostic (4.01e-1)" "unprognostic (8.31e-2)" "unprognostic (6.09e-3)" "potential prognostic favorable (7.38e-4)" "unprognostic (4.90e-3)" "unprognostic (2.49e-2)" "potential prognostic unfavorable (1.11e-5)" "unprognostic (2.68e-3)" "unprognostic (3.01e-2)" "unprognostic (2.38e-2)" "unprognostic (2.70e-1)" "unprognostic (2.08e-1)" "unprognostic (9.43e-2)" "unprognostic (3.80e-2)" "unprognostic (3.68e-2)" "unprognostic (5.23e-2)" "unprognostic (3.98e-1)" "unprognostic (1.54e-2)" "unprognostic (2.71e-2)" "unprognostic (2.98e-1)" "unprognostic (2.21e-1)" "unprognostic (6.96e-2)" "unprognostic (8.78e-2)" "unprognostic (4.85e-2)" SSU72P2 ENSG00000284306 "SSU72 pseudogene 2" 11 4242056-4242640 "Enzymes, Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 27: Breast cancer - Unknown function" SSU72P3 ENSG00000284546 "SSU72 pseudogene 3" 11 4329865-4330449 "Enzymes, Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 27: Breast cancer - Unknown function" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" SSU72P4 ENSG00000283873 "SSU72 pseudogene 4" 11 4287499-4288083 "Enzymes, Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 27: Breast cancer - Unknown function" SSU72P5 ENSG00000284018 "SSU72 pseudogene 5" 11 4233288-4233872 "Enzymes, Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 27: Breast cancer - Unknown function" SSU72P7 ENSG00000284438 "SSU72 pseudogene 7" 11 4338660-4339244 "Enzymes, Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 27: Breast cancer - Unknown function" SSU72P8 ENSG00000230268 "SSU72 pseudogene 8" 7 124476371-124476955 "Enzymes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Tissue enriched" "Detected in single" 13 "testis: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Spermatocytes" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 47: Leukemia - Hemostasis" SSUH2 "C3orf32, fls485, ssu-2" ENSG00000125046 "Ssu-2 homolog" Q9Y2M2 3 8619386-8745040 "Disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 6.2;testis: 5.2" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 125.6;Early spermatids: 140.5;Enterocytes: 20.5;Late primary spermatocytes: 50.5;Late spermatids: 113.6;Myonuclei: 29.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 2.8" "Minor Salivary Gland - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Fibroblasts" "Not detected" "Not detected" "Not detected" "Not detected" HPA049777 Approved NA NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 18: Liver cancer - Metabolism" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 130 "HPA049777: " "unprognostic (4.60e-2)" "unprognostic (5.32e-2)" "unprognostic (2.25e-3)" "unprognostic (8.45e-2)" "unprognostic (7.88e-2)" "unprognostic (1.43e-2)" SSX1 CT5.1 ENSG00000126752 "SSX family member 1" Q16384 X 48255392-48267444 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 20 "testis: 6.9" "Group enriched" "Detected in some" 5 "Differentiating spermatogonia: 20.6;Early primary spermatocytes: 38.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 11.7" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 50.5" "Testis - Spermatocytes" "HPA045683, HPA071685" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 15: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 3: Early primary spermatocytes - Early meiosis" 4 "Nucleoplasm, Nucleoli" "HPA045683: , HPA071685: " "unprognostic (3.30e-1)" "potential prognostic unfavorable (3.46e-4)" "unprognostic (2.15e-3)" "unprognostic (1.03e-1)" "unprognostic (1.62e-1)" "unprognostic (3.41e-2)" "unprognostic (1.10e-2)" "unprognostic (1.05e-1)" "unprognostic (2.45e-1)" "unprognostic (1.04e-1)" SSX2 "CT5.2a, HD21, HOM-MEL-40, MGC119055, MGC15364, MGC3884, SSX" ENSG00000241476 "SSX family member 2" Q16385 X 52696896-52707178 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 52 "testis: 15.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 41.0" "HPA045683, HPA071685" Enhanced Approved Nucleoplasm,Nucleoli NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" 15 "Nucleoplasm, Nucleoli" "HPA045683: , HPA071685: " SSX2B CT5.2b ENSG00000268447 "SSX family member 2B" Q16385 X 52751132-52790305 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 51 "testis: 15.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 41.9" "HPA045683, HPA071685" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 44: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 80: Oligodendrocytes - Myelination" 9 "Nucleoplasm, Nucleoli" "HPA045683: , HPA071685: " "unprognostic (2.36e-1)" "potential prognostic unfavorable (4.40e-4)" "unprognostic (2.93e-2)" "unprognostic (7.20e-3)" "unprognostic (1.48e-1)" "potential prognostic unfavorable (6.08e-4)" SSX2IP hMsd1 ENSG00000117155 "SSX family member 2 interacting protein" Q9Y2D8 1 84643706-84690803 "Predicted intracellular proteins" "Cell adhesion, Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 109.9;testis: 98.7" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 345.7;Early spermatids: 958.1;Late primary spermatocytes: 306.0;Late spermatids: 1688.0;Megakaryocytes: 216.4;Platelets: 540.4;Rod photoreceptor cells: 273.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Pituitary gland - Corticotropes, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027306, HPA075946" Supported Supported "Centriolar satellite,Centrosome,Basal body,Acrosome,Equatorial segment,Principal piece" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 42: Retina - Visual perception" "Cluster 53: Neurons - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 125 "Centriolar satellite, Centrosome, Basal body" "Acrosome, Equatorial segment, Principal piece" "HPA027306: , HPA075946: " "unprognostic (3.18e-1)" "unprognostic (3.89e-2)" "unprognostic (8.20e-2)" "unprognostic (1.99e-1)" "potential prognostic favorable (1.87e-4)" "unprognostic (5.98e-2)" "unprognostic (1.97e-1)" "unprognostic (4.44e-2)" "unprognostic (7.83e-2)" "unprognostic (1.48e-3)" "unprognostic (8.90e-3)" "unprognostic (1.71e-1)" "unprognostic (5.98e-3)" "unprognostic (5.49e-3)" "unprognostic (3.11e-2)" "unprognostic (2.41e-3)" "unprognostic (1.75e-2)" "unprognostic (3.48e-1)" "unprognostic (1.18e-1)" "unprognostic (5.09e-2)" "unprognostic (1.18e-1)" "unprognostic (2.52e-1)" "unprognostic (5.94e-2)" "unprognostic (3.54e-1)" "unprognostic (1.03e-3)" "unprognostic (6.51e-3)" "unprognostic (2.09e-1)" "unprognostic (6.24e-2)" "unprognostic (8.52e-3)" "unprognostic (6.22e-2)" "unprognostic (8.68e-2)" SSX3 CT5.3 ENSG00000165584 "SSX family member 3" Q99909 X 48346427-48356707 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 60 "testis: 12.0" "Group enriched" "Detected in some" 8 "Differentiating spermatogonia: 178.2;Early primary spermatocytes: 136.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Liver Hepatocellular Carcinoma (TCGA): 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 19.2" "Testis - Spermatocytes" "HPA045683, HPA071685" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 1: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 13 "Nucleoplasm, Nucleoli" "HPA045683: , HPA071685: " "potential prognostic unfavorable (3.65e-4)" SSX4 CT5.4 ENSG00000268009 "SSX family member 4" O60224 X 48383516-48393347 "Cancer-related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 15 "testis: 2.9" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Ovary Serous Cystadenocarcinoma (TCGA): 5.2;Stomach Adenocarcinoma (TCGA): 4.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 11.6;lymphoma: 5.7" "HPA045683, HPA071685" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 53: Squamous epithelial cells - Keratinization" 4 "Nucleoplasm, Nucleoli" "HPA045683: , HPA071685: " "unprognostic (2.65e-2)" "potential prognostic unfavorable (6.84e-6)" "unprognostic (1.09e-1)" "unprognostic (1.71e-1)" "unprognostic (4.98e-3)" SSX4B OTTHUMT00000056510 ENSG00000269791 "SSX family member 4B" O60224 X 48402082-48411960 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 9 "testis: 1.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Ovary Serous Cystadenocarcinoma (TCGA): 1.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Bladder cancer: 4.3;lymphoma: 4.6;Myeloma: 9.5" "HPA045683, HPA071685" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 47: Testis - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" 2 "Nucleoplasm, Nucleoli" "HPA045683: , HPA071685: " "unprognostic (8.84e-2)" SSX5 ENSG00000165583 "SSX family member 5" O60225 X 48186220-48196795 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Differentiating spermatogonia: 4.3;Early primary spermatocytes: 5.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045683, HPA071685" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 32: Cerebral cortex - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 1 "Nucleoplasm, Nucleoli" "HPA045683: , HPA071685: " SSX7 ENSG00000187754 "SSX family member 7" Q7RTT5 X 52644061-52654900 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Bone cancer: 1.1" "HPA045683, HPA071685" Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 6: Non-specific - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 4 "Nucleoplasm, Nucleoli" "HPA045683: , HPA071685: " "unprognostic (1.56e-2)" ST13 "FAM10A1, HIP, HSPABP1, P48, SNC6" ENSG00000100380 "ST13 Hsp70 interacting protein" P50502 22 40824535-40856639 "Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epididymal efferent duct absorptive cells: 932.4;Late spermatids: 1444.5;Ovarian stromal cells: 975.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043233, HPA046412, HPA047114, HPA047116" Enhanced Approved "Primary cilium,Primary cilium tip,Basal body,Cytosol" NA NA 8200000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 66: Non-specific - Mitochondria" "Cluster 94: Gonadal somatic cells - Mixed function" 25 Cytosol "Primary cilium, Primary cilium tip, Basal body" "HPA043233: , HPA046412: , HPA047114: , HPA047116: " "unprognostic (1.51e-2)" "unprognostic (6.67e-2)" "unprognostic (8.63e-2)" "unprognostic (1.17e-1)" "unprognostic (1.28e-1)" "unprognostic (5.16e-2)" "unprognostic (8.03e-2)" "unprognostic (7.61e-2)" "unprognostic (3.85e-3)" "unprognostic (2.64e-1)" "validated prognostic favorable (1.14e-12)" "validated prognostic favorable (2.62e-5)" "unprognostic (3.71e-2)" "unprognostic (3.62e-3)" "unprognostic (3.32e-2)" "unprognostic (5.26e-3)" "unprognostic (5.97e-2)" "unprognostic (1.72e-1)" "unprognostic (1.19e-1)" "unprognostic (1.90e-1)" "unprognostic (2.73e-2)" "unprognostic (1.44e-1)" "unprognostic (2.15e-1)" "unprognostic (7.10e-2)" "unprognostic (4.14e-3)" "unprognostic (3.07e-1)" "unprognostic (6.26e-2)" "unprognostic (8.56e-2)" "unprognostic (1.83e-1)" "unprognostic (7.85e-2)" "unprognostic (4.83e-2)" ST14 "CAP3, HAI, MT-SP1, PRSS14, SNC19, TMPRSS14" ENSG00000149418 "ST14 transmembrane serine protease matriptase" Q9Y5Y6 11 130159782-130210362 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant, Hypotrichosis, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 108.0;intestine: 136.4" "Cell type enhanced" "Detected in many" "Colonocytes: 540.5;Endometrial glandular cells: 340.4;Endometrial luminal cells: 312.6;Enterocytes: 446.9;Esophageal apical cells: 546.6;Esophageal suprabasal cells: 306.1;Ocular epithelial cells: 475.3;Salivary ionocytes: 309.1;Urothelial cells: 451.4" "Cell type enhanced" "Detected in some" "leukocyte: 3.2" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "thalamus: 19.4" "Immune cell enriched" "Detected in many" 4 "plasmacytoid DC: 25.1" "Lineage enriched" "Detected in many" 5 "dendritic cells: 25.1" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Breast glandular cells, Colon - Colon enterocytes, Heart muscle - Macrophages, Skeletal muscle - Macrophages, Testis - Late spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA047014, HPA056258" Enhanced Approved Nucleoplasm,Vesicles NA NA 1600000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 17: Intestine - Digestion" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 19 "Nucleoplasm, Vesicles" "HPA047014: , HPA056258: " "unprognostic (3.14e-2)" "unprognostic (5.20e-2)" "unprognostic (3.42e-2)" "unprognostic (2.98e-2)" "unprognostic (1.34e-1)" "unprognostic (1.58e-2)" "unprognostic (2.62e-2)" "unprognostic (1.23e-1)" "unprognostic (2.61e-1)" "unprognostic (2.83e-1)" "unprognostic (2.62e-2)" "unprognostic (1.03e-1)" "potential prognostic favorable (1.47e-7)" "unprognostic (2.09e-1)" "unprognostic (4.01e-1)" "unprognostic (5.04e-2)" "unprognostic (1.04e-3)" "unprognostic (1.31e-1)" "unprognostic (4.20e-2)" "unprognostic (3.32e-1)" "unprognostic (4.22e-1)" "unprognostic (2.85e-3)" "unprognostic (3.58e-1)" "unprognostic (2.63e-1)" "unprognostic (2.81e-2)" "unprognostic (1.17e-1)" "unprognostic (2.94e-1)" "unprognostic (4.76e-2)" "unprognostic (3.18e-1)" "unprognostic (5.99e-2)" "unprognostic (2.65e-2)" ST18 "KIAA0535, NZF-3, NZF3, ZC2H2C3, ZC2HC10, ZNF387" ENSG00000147488 "ST18 C2H2C-type zinc finger transcription factor" O60284 8 52110838-52460959 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 21.9;retina: 7.5" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 4251.0" "Group enriched" "Detected in all" 8 "committed oligodendrocyte precursor: 1673.2;oligodendrocyte: 6059.6" "Group enriched" "Detected in some" 4 "Glioblastoma Multiforme (TCGA): 1.2;Pancreatic Adenocarcinoma (TCGA): 1.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 5.7" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Kidney - Proximal tubular cells, Minor Salivary Gland - Macrophages, Pancreas - Alpha cells, Pancreas - Beta cells, Pituitary gland - Gonadotropes, Stomach - Gastric enteroendocrine cells" "Region enhanced" "Detected in all" "cerebellum: 40.2" "Low region specificity" "Detected in all" HPA044919 Uncertain NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 11: White matter - Signal transduction" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 80: Oligodendrocytes - Myelination" "HPA044919: " "unprognostic (2.91e-1)" "unprognostic (2.02e-1)" "unprognostic (3.84e-3)" "potential prognostic favorable (9.71e-4)" "unprognostic (3.41e-2)" ST20-MTHFS ENSG00000259332 "ST20-MTHFS readthrough" 15 79845150-79923754 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 90.0" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.3;Endometrial secretory cells: 1.6;Epicardial cells: 6.8;Monocyte progenitors: 1.2;monocytes: 3.2;Neutrophils: 14.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 562.2" "Lineage enriched" "Detected in all" 4 "granulocytes: 562.2" "Low cancer specificity" "Detected in all" HPA008067 Uncertain NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 58: Non-specific - Nuclear processes" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" "HPA008067: " "unprognostic (3.48e-2)" "unprognostic (3.52e-2)" "unprognostic (1.11e-3)" "unprognostic (3.21e-1)" "unprognostic (8.40e-2)" "potential prognostic unfavorable (4.49e-5)" "unprognostic (6.98e-2)" "unprognostic (8.38e-2)" "potential prognostic favorable (2.92e-7)" "unprognostic (2.45e-2)" "unprognostic (8.01e-3)" "potential prognostic favorable (1.25e-8)" "unprognostic (2.04e-2)" "unprognostic (7.73e-2)" "unprognostic (2.33e-1)" "unprognostic (1.11e-1)" "unprognostic (2.17e-1)" "unprognostic (2.70e-2)" "unprognostic (1.11e-1)" "unprognostic (1.66e-1)" "unprognostic (2.60e-1)" "unprognostic (4.30e-2)" "unprognostic (1.50e-1)" "unprognostic (2.20e-2)" "unprognostic (1.04e-1)" "unprognostic (3.32e-1)" "unprognostic (2.57e-1)" "unprognostic (3.37e-1)" ST3GAL1 "SIAT4A, SIATFL, ST3GalA.1, ST3O" ENSG00000008513 "ST3 beta-galactoside alpha-2,3-sialyltransferase 1" Q11201 8 133454848-133571940 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Innate lymphoid cells: 362.9;Myonuclei: 307.1;Neutrophils: 310.9" "Cell type enhanced" "Detected in all" "endothelial cell: 213.5;leukocyte: 214.1" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 88.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040466 Approved "Intracellular and membrane" Enzyme NA NA 390000 "Cluster 22: Eosinophils - Transcription" "Cluster 76: Non-specific - Metabolism" "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 103: Non-specific - Basic cellular processes" 4 "HPA040466: " "unprognostic (8.05e-2)" "unprognostic (3.23e-3)" "unprognostic (2.04e-1)" "potential prognostic unfavorable (6.79e-4)" "unprognostic (4.43e-3)" "unprognostic (1.42e-1)" "unprognostic (8.40e-3)" "unprognostic (3.50e-3)" "unprognostic (9.78e-2)" "unprognostic (1.35e-1)" "potential prognostic favorable (1.47e-4)" "unprognostic (1.29e-3)" "unprognostic (1.76e-1)" "unprognostic (5.59e-2)" "unprognostic (4.53e-2)" "unprognostic (2.49e-1)" "unprognostic (7.69e-2)" "unprognostic (2.81e-1)" "unprognostic (5.17e-2)" "unprognostic (2.59e-2)" "unprognostic (1.40e-1)" "unprognostic (1.84e-3)" "unprognostic (3.61e-3)" "unprognostic (3.98e-1)" "unprognostic (2.05e-1)" "unprognostic (8.67e-2)" "unprognostic (1.34e-1)" "unprognostic (4.07e-2)" "unprognostic (8.14e-2)" "unprognostic (3.65e-2)" "unprognostic (1.97e-2)" ST3GAL2 "SIAT4B, ST3GalA.2, ST3GALII" ENSG00000157350 "ST3 beta-galactoside alpha-2,3-sialyltransferase 2" Q16842 16 70375977-70439237 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 371.6;pDCs: 173.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Endothelial cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017270 Approved Uncertain Vesicles "Intracellular and membrane" Enzyme NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 47: Leukemia - Hemostasis" "Cluster 24: Neutrophils - Innate immunity signal integration" 1 Vesicles "HPA017270: " "unprognostic (4.09e-2)" "unprognostic (1.52e-1)" "unprognostic (4.72e-2)" "unprognostic (1.12e-2)" "unprognostic (1.44e-1)" "unprognostic (1.09e-1)" "unprognostic (1.78e-1)" "unprognostic (1.51e-3)" "unprognostic (7.45e-2)" "unprognostic (2.11e-1)" "unprognostic (1.70e-1)" "unprognostic (8.45e-2)" "unprognostic (2.55e-2)" "potential prognostic unfavorable (4.10e-5)" "unprognostic (2.15e-2)" "unprognostic (2.78e-2)" "unprognostic (2.14e-2)" "unprognostic (1.50e-2)" "unprognostic (4.82e-3)" "unprognostic (6.96e-2)" "unprognostic (5.03e-2)" "unprognostic (1.69e-3)" "unprognostic (5.18e-2)" "unprognostic (7.45e-2)" "unprognostic (2.80e-1)" "unprognostic (8.29e-2)" "unprognostic (9.27e-2)" "unprognostic (9.84e-2)" "unprognostic (1.67e-1)" "unprognostic (5.30e-3)" "unprognostic (8.47e-3)" ST3GAL3 "MRT12, SIAT6" ENSG00000126091 "ST3 beta-galactoside alpha-2,3-sialyltransferase 3" Q11203 1 43705824-43931165 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 82.4;tongue: 77.3" "Group enriched" "Detected in many" 4 "Astrocytes: 115.4;Bergmann glia: 92.7;Brain excitatory neurons: 130.2;Brain inhibitory neurons: 147.1;Choroid plexus epithelial cells: 176.9;Ependymal cells: 134.7;Microglia: 120.4;Oligodendrocyte progenitor cells: 100.1;Oligodendrocytes: 101.5;Other brain neurons: 131.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051102 Uncertain "Intracellular and membrane" Enzyme NA NA "Cluster 24: Non-specific - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 22: Non-specific - Basic cellular functions" 2 "HPA051102: " "unprognostic (3.12e-3)" "unprognostic (2.61e-1)" "unprognostic (5.16e-3)" "unprognostic (1.79e-1)" "unprognostic (2.52e-1)" "unprognostic (2.99e-1)" "unprognostic (1.39e-2)" "unprognostic (1.13e-2)" "unprognostic (6.67e-2)" "unprognostic (3.61e-3)" "unprognostic (1.77e-1)" "unprognostic (9.63e-2)" "unprognostic (2.20e-3)" "unprognostic (1.91e-2)" "unprognostic (6.56e-2)" "unprognostic (4.20e-2)" "unprognostic (3.85e-1)" "unprognostic (1.37e-1)" "potential prognostic favorable (4.74e-5)" "unprognostic (1.99e-1)" "unprognostic (1.35e-1)" "unprognostic (1.74e-3)" "unprognostic (2.85e-1)" "unprognostic (1.54e-1)" "potential prognostic unfavorable (1.69e-4)" "unprognostic (3.71e-3)" "unprognostic (2.12e-1)" "unprognostic (7.57e-2)" "unprognostic (6.44e-2)" "unprognostic (5.30e-2)" "unprognostic (1.56e-1)" ST3GAL4 "CGS23, FLJ11867, NANTA3, SAT3, SIAT4, SIAT4C, STZ" ENSG00000110080 "ST3 beta-galactoside alpha-2,3-sialyltransferase 4" Q11206 11 126355640-126440344 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Esophageal apical cells: 1313.8;Syncytiotrophoblasts: 1341.6" "Cell type enhanced" "Detected in all" "oligodendrocyte: 137.1" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 214.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 112.4;neutrophil: 72.1;plasmacytoid DC: 93.9" "Group enriched" "Detected in many" 12 "dendritic cells: 93.9;granulocytes: 112.4" "Cancer enriched" "Detected in all" 4 "skin cancer: 242.2" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells, Breast - Fibroblasts, Pituitary gland - Gonadotropes, Prostate - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049827 Approved "Intracellular and membrane" Enzyme NA NA 15000 "Cluster 41: Basophils - Unknown function" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 30: White matter - Myelination" "Cluster 69: Skin cancer - ECM organization" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" "HPA049827: " "unprognostic (7.24e-2)" "unprognostic (1.63e-2)" "unprognostic (5.20e-2)" "unprognostic (5.81e-2)" "unprognostic (1.68e-1)" "unprognostic (4.85e-2)" "unprognostic (3.76e-2)" "unprognostic (1.63e-1)" "unprognostic (4.55e-2)" "unprognostic (2.49e-1)" "unprognostic (6.75e-3)" "unprognostic (1.93e-1)" "unprognostic (3.42e-2)" "unprognostic (5.90e-3)" "unprognostic (2.01e-3)" "potential prognostic unfavorable (1.76e-4)" "unprognostic (1.41e-2)" "unprognostic (2.81e-2)" "unprognostic (4.38e-2)" "unprognostic (3.87e-3)" "unprognostic (3.50e-1)" "unprognostic (1.75e-2)" "unprognostic (7.22e-3)" "unprognostic (1.52e-1)" "unprognostic (1.44e-1)" "unprognostic (1.27e-3)" "unprognostic (2.11e-1)" "unprognostic (1.31e-2)" "unprognostic (1.76e-1)" "unprognostic (5.40e-3)" "unprognostic (1.28e-2)" ST3GAL5 "SIAT9, SIATGM3S, ST3GalV" ENSG00000115525 "ST3 beta-galactoside alpha-2,3-sialyltransferase 5" Q9UNP4 2 85837120-85905199 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 45.9" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 522.1;Alveolar cells type 2: 234.0;Oligodendrocytes: 208.2;Pituicytes/FSCs: 618.4;Retinal pigment epithelial cells: 558.4;Urothelial cells: 260.5" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Thyroid Carcinoma (TCGA): 103.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "skin cancer: 28.1" "Breast - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034708, HPA040425, HPA068928" Uncertain Approved Vesicles NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 36: Brain & Liver - Signaling" "Cluster 11: White matter - Signal transduction" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" Vesicles "HPA034708: , HPA040425: , HPA068928: " "unprognostic (1.18e-1)" "unprognostic (1.33e-1)" "unprognostic (3.63e-3)" "unprognostic (2.44e-1)" "unprognostic (9.58e-2)" "unprognostic (2.56e-1)" "unprognostic (1.95e-1)" "unprognostic (3.73e-3)" "unprognostic (3.39e-1)" "unprognostic (4.00e-2)" "potential prognostic unfavorable (6.47e-4)" "unprognostic (4.99e-2)" "unprognostic (1.11e-3)" "unprognostic (2.62e-2)" "unprognostic (9.15e-2)" "potential prognostic favorable (7.98e-4)" "unprognostic (1.73e-1)" "unprognostic (2.78e-2)" "unprognostic (1.12e-1)" "unprognostic (1.32e-1)" "unprognostic (1.02e-1)" "unprognostic (1.11e-1)" "unprognostic (7.47e-2)" "unprognostic (3.47e-2)" "unprognostic (1.54e-2)" "unprognostic (3.55e-2)" "unprognostic (5.71e-2)" "unprognostic (1.71e-2)" "unprognostic (7.05e-3)" "unprognostic (2.28e-3)" "unprognostic (1.05e-1)" ST3GAL6 "SIAT10, ST3GALVI" ENSG00000064225 "ST3 beta-galactoside alpha-2,3-sialyltransferase 6" Q9Y274 3 98732236-98821201 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 21.4;liver: 39.3" "Cell type enhanced" "Detected in many" "Bergmann glia: 721.6;Cardiomyocytes: 555.7;Melanocytes: 428.0;Podocytes: 1444.3;Salivary acinar cells: 390.5" "Cell type enhanced" "Detected in all" "Bergmann glia: 728.9" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 26.8;Skin Cutaneous Melanoma (TCGA): 39.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 41.3;neutrophil: 50.9" "Group enriched" "Detected in many" 123 "dendritic cells: 19.8;granulocytes: 50.9;monocytes: 14.6" "Group enriched" "Detected in many" 5 "Myeloma: 32.4;Neuroblastoma: 15.7;skin cancer: 37.0" "Adipose subcutaneous - Adipocytes (Subcutaneous), Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018792 Approved NA NA 1700000 "Cluster 21: Neutrophils - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 43: Hindbrain - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 57: Podocytes - Glomerular filtration" "HPA018792: " "unprognostic (2.24e-3)" "unprognostic (3.01e-1)" "unprognostic (1.06e-1)" "unprognostic (2.17e-3)" "unprognostic (6.55e-2)" "unprognostic (1.17e-2)" "potential prognostic favorable (4.31e-4)" "unprognostic (3.28e-1)" "unprognostic (9.08e-3)" "potential prognostic favorable (1.14e-4)" "unprognostic (2.43e-1)" "unprognostic (1.00e-1)" "unprognostic (3.79e-2)" "unprognostic (2.30e-3)" "unprognostic (5.94e-3)" "unprognostic (6.48e-2)" "unprognostic (5.06e-2)" "unprognostic (2.54e-1)" "unprognostic (1.61e-1)" "unprognostic (2.46e-1)" "unprognostic (8.13e-2)" "unprognostic (1.02e-2)" "unprognostic (8.62e-2)" "unprognostic (3.85e-1)" "unprognostic (3.72e-2)" "potential prognostic unfavorable (1.68e-4)" "unprognostic (6.09e-2)" "unprognostic (1.14e-1)" "unprognostic (1.48e-2)" ST6GAL1 "CDw75, SIAT1" ENSG00000073849 "ST6 beta-galactoside alpha-2,6-sialyltransferase 1" P15907 3 186930325-187078553 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "liver: 463.6;lymphoid tissue: 138.6" "Cell type enhanced" "Detected in many" "B-cells: 990.0;Hepatocytes: 694.6;Microglia: 2267.8;Plasma cells: 1276.2;Renal collecting duct principal cells: 794.8;Salivary duct cells: 573.3" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 2589.3;endothelial cell: 1292.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "lymphoma: 138.9;Myeloma: 151.6" "Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Spleen - B-cells (Spleen), Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB080031 Enhanced "Secreted to blood" Enzyme NA NA 15000000 3200000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 20: Myeloma - Immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" "CAB080031: " "unprognostic (1.25e-2)" "unprognostic (8.21e-3)" "unprognostic (5.19e-2)" "unprognostic (3.10e-1)" "unprognostic (1.44e-1)" "potential prognostic favorable (9.56e-4)" "unprognostic (1.21e-1)" "unprognostic (2.25e-2)" "unprognostic (2.01e-2)" "unprognostic (1.78e-1)" "unprognostic (5.94e-2)" "unprognostic (3.89e-2)" "unprognostic (2.04e-1)" "unprognostic (3.01e-3)" "unprognostic (3.23e-2)" "unprognostic (7.21e-3)" "unprognostic (7.83e-3)" "unprognostic (1.46e-1)" "unprognostic (5.30e-2)" "unprognostic (1.93e-2)" "unprognostic (1.10e-1)" "unprognostic (3.78e-1)" "unprognostic (3.19e-1)" "unprognostic (5.84e-2)" "unprognostic (1.92e-2)" "unprognostic (1.82e-2)" "unprognostic (1.53e-1)" "unprognostic (6.44e-3)" "unprognostic (1.04e-1)" "unprognostic (1.08e-1)" "unprognostic (1.39e-1)" ST6GAL2 "KIAA1877, SIAT2, St6GalII" ENSG00000144057 "ST6 beta-galactoside alpha-2,6-sialyltransferase 2" Q96JF0 2 106801600-106887108 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "blood vessel: 33.5;brain: 12.5;thyroid gland: 27.2" "Cell type enhanced" "Detected in many" "Astrocytes: 79.0;Bergmann glia: 76.5;Brain excitatory neurons: 57.1;Brain inhibitory neurons: 67.2;Hepatic stellate cells: 58.1;Megakaryocyte progenitors: 149.0;Megakaryocyte-Erythroid progenitors: 71.3;Oligodendrocyte progenitor cells: 182.5;Other brain neurons: 72.1;Retinal amacrine cells: 74.1;Sertoli cells: 151.4" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 7 "Thyroid Carcinoma (TCGA): 31.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Neuroblastoma: 15.8" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Smooth muscle cells, Heart muscle - Smooth muscle cells, Liver - Hepatic stellate cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014459 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA 6300 "Cluster 74: Non-specific - Signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 109: Neurons - Neuronal signaling" "Nucleoli fibrillar center" Nucleoplasm "HPA014459: " "unprognostic (9.74e-2)" "unprognostic (3.25e-1)" "unprognostic (2.55e-2)" "unprognostic (1.88e-2)" "unprognostic (4.14e-3)" "unprognostic (3.94e-3)" "unprognostic (7.48e-2)" "unprognostic (2.48e-3)" "unprognostic (1.87e-1)" "unprognostic (2.93e-2)" "unprognostic (8.20e-2)" "unprognostic (1.54e-1)" "unprognostic (7.10e-3)" "unprognostic (8.71e-3)" "unprognostic (5.09e-2)" "unprognostic (1.27e-3)" "unprognostic (1.05e-1)" "unprognostic (2.98e-1)" "unprognostic (3.27e-1)" "unprognostic (7.95e-2)" "unprognostic (3.71e-2)" "unprognostic (2.36e-1)" "unprognostic (1.41e-1)" ST6GALNAC1 "SIAT7A, ST6GalNAcI" ENSG00000070526 "ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1" Q9NSC7 17 76624761-76643786 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 57.5;intestine: 183.8;stomach 1: 61.3" "Cell type enhanced" "Detected in many" "Colonocytes: 132.7;Conjunctival goblet cells: 133.0;Endometrial ciliated cells: 102.1;Endometrial glandular cells: 103.7;Endometrial secretory cells: 116.7;Enteric transient amplifying cells: 108.4;Esophageal apical cells: 309.6;Goblet cells: 811.2;Parietal cells: 224.5;Respiratory basal cells: 143.0;Respiratory ciliated cells: 125.2;Respiratory deuterosomal cells: 133.7;Respiratory secretory cells: 231.6" "Cell type enriched" "Detected in some" 16 "endothelial cell: 107.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "memory CD4 T-cell: 8.9;naive CD4 T-cell: 3.4" "Lineage enriched" "Detected in single" 33 "T-cells: 8.9" "Cancer enhanced" "Detected in many" "prostate cancer: 16.8" "Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Urothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA014767, HPA014975" Enhanced Approved "Nucleoplasm,Golgi apparatus" NA NA 1300000 "Cluster 31: T-cells - T-cell receptor" "Cluster 17: Intestine - Digestion" "Cluster 47: Endothelial cells - Vasculature" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 70: Intestinal goblet cells - Mucin production" 2 "Golgi apparatus" Nucleoplasm "HPA014767: , HPA014975: " "unprognostic (1.04e-1)" "unprognostic (1.15e-1)" "unprognostic (4.62e-2)" "unprognostic (1.20e-3)" "unprognostic (8.00e-2)" "unprognostic (7.34e-3)" "unprognostic (3.84e-2)" "unprognostic (6.05e-2)" "potential prognostic favorable (1.11e-4)" "unprognostic (2.67e-2)" "unprognostic (5.68e-2)" "unprognostic (2.86e-1)" "unprognostic (5.87e-2)" "unprognostic (1.37e-1)" "unprognostic (2.94e-2)" "unprognostic (2.09e-1)" "unprognostic (6.14e-3)" "potential prognostic favorable (3.50e-4)" "unprognostic (1.66e-1)" "unprognostic (1.63e-2)" "unprognostic (1.76e-3)" "unprognostic (6.26e-2)" "unprognostic (1.71e-1)" "unprognostic (6.12e-2)" "unprognostic (2.31e-1)" ST6GALNAC2 "SIAT7, SIAT7B, SIATL1, ST6GalNAII, STHM" ENSG00000070731 "ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2" Q9UJ37 17 76565377-76586956 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 123.4" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 66.0;Ependymal cells: 61.8;Melanocytes: 75.2;Müller glia: 76.4;Neutrophils: 114.6;Prostatic hillock cells: 59.8;Respiratory basal cells: 58.7;Respiratory ciliated cells: 84.5;Retinal pigment epithelial cells: 89.5;Rod photoreceptor cells: 206.7;Schwann cells: 100.8" "Group enriched" "Detected in many" 7 "choroid plexus epithelial cell: 69.3;ependymal cell: 84.1" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 93.8" "Region enriched" "Detected in many" 5 "choroid plexus: 69.7" "Immune cell enriched" "Detected in some" 9 "neutrophil: 47.2" "Lineage enriched" "Detected in many" 16 "granulocytes: 47.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 30.5;skin cancer: 29.4" "Adrenal gland - Adrenal cortex cells, Breast - Breast myoepithelial cells, Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 27: Breast cancer - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" "unprognostic (1.05e-2)" "unprognostic (3.48e-2)" "unprognostic (4.65e-2)" "unprognostic (9.52e-2)" "unprognostic (3.98e-1)" "unprognostic (6.47e-2)" "unprognostic (2.73e-1)" "unprognostic (4.36e-2)" "unprognostic (1.71e-2)" "unprognostic (5.64e-2)" "unprognostic (7.50e-3)" "unprognostic (2.70e-2)" "unprognostic (4.23e-3)" "unprognostic (7.01e-2)" "unprognostic (1.15e-2)" "unprognostic (1.64e-2)" "unprognostic (6.13e-2)" "unprognostic (2.98e-2)" "unprognostic (3.26e-1)" "unprognostic (1.64e-1)" "unprognostic (1.13e-1)" "unprognostic (7.78e-3)" "unprognostic (2.64e-3)" "unprognostic (1.81e-1)" "potential prognostic unfavorable (3.52e-4)" "unprognostic (1.04e-1)" "unprognostic (2.34e-2)" "unprognostic (7.03e-2)" "unprognostic (1.03e-1)" "unprognostic (8.57e-2)" ST6GALNAC3 SIAT7C ENSG00000184005 "ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3" Q8NDV1 1 76074746-76634603 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 1708.3;Lymphatic endothelial cells: 1236.0;Microglia: 2471.3;Neutrophil progenitors: 1412.7;Neutrophils: 3519.9;Podocytes: 8623.1;Somatotrophs: 1225.8;Thyrotrophs: 886.1;Tuft cells: 1026.0;Vascular endothelial cells: 1120.8" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 2902.8;endothelial cell: 3210.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Neuroblastoma: 13.8;skin cancer: 12.1;testis cancer: 7.6;thyroid cancer: 3.6" "Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Breast - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Podocytes, Liver - Vascular endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054566, HPA055399" Uncertain Approved Nucleoplasm NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 57: Podocytes - Glomerular filtration" 1 Nucleoplasm "HPA054566: , HPA055399: " "unprognostic (9.01e-2)" "unprognostic (3.55e-1)" "unprognostic (3.36e-1)" "unprognostic (1.03e-1)" "unprognostic (2.68e-2)" "unprognostic (1.04e-1)" "validated prognostic favorable (5.82e-9)" "validated prognostic favorable (3.31e-4)" "potential prognostic favorable (5.44e-5)" "unprognostic (2.63e-1)" "unprognostic (5.94e-2)" "unprognostic (9.99e-2)" "unprognostic (2.35e-1)" "unprognostic (3.43e-1)" "unprognostic (4.04e-2)" "unprognostic (1.79e-2)" "unprognostic (1.74e-1)" "unprognostic (4.32e-3)" "unprognostic (6.72e-2)" "unprognostic (1.25e-1)" "unprognostic (5.52e-2)" ST6GALNAC4 "SIAT3C, SIAT7D, ST6GALNACIV" ENSG00000136840 "ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4" Q9H4F1 9 127907886-127917041 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 69.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 70.5;Decidual stromal cells: 49.0;Erythrocyte progenitors: 59.6;Megakaryocytes: 74.2;pDCs: 98.7;Plasma cells: 87.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 9 "plasmacytoid DC: 234.3" "Lineage enriched" "Detected in all" 9 "dendritic cells: 234.3" "Low cancer specificity" "Detected in all" "Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009042 Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 24: Non-specific - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 55: Lymphoma - Immune response" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 1 "Golgi apparatus" Nucleoplasm "HPA009042: " "unprognostic (1.25e-1)" "potential prognostic unfavorable (1.26e-4)" "unprognostic (2.99e-1)" "unprognostic (2.91e-1)" "unprognostic (1.14e-2)" "unprognostic (8.88e-3)" "unprognostic (1.55e-1)" "unprognostic (2.33e-1)" "unprognostic (2.08e-1)" "unprognostic (1.43e-1)" "unprognostic (8.68e-3)" "unprognostic (1.02e-1)" "unprognostic (1.40e-1)" "potential prognostic unfavorable (7.79e-8)" "unprognostic (2.63e-2)" "unprognostic (6.85e-3)" "unprognostic (1.33e-1)" "potential prognostic unfavorable (1.82e-4)" "unprognostic (2.43e-1)" "unprognostic (3.58e-3)" "unprognostic (2.99e-1)" "unprognostic (8.53e-2)" "unprognostic (2.53e-1)" "unprognostic (3.78e-1)" "unprognostic (1.44e-1)" "unprognostic (9.51e-2)" "unprognostic (7.97e-2)" "unprognostic (1.51e-2)" "unprognostic (1.13e-1)" "unprognostic (5.83e-2)" "unprognostic (2.29e-1)" ST6GALNAC5 "MGC3184, SIAT7E, ST6GalNAcV" ENSG00000117069 "ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5" Q9BVH7 1 76867480-77067546 "Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 338.6;Alveolar cells type 1: 409.2;Brain excitatory neurons: 701.8;Brain inhibitory neurons: 429.3;Corticotrophs: 540.6;Lactotrophs: 525.2;Other brain neurons: 210.9;Pituitary stem cells: 531.7;Retinal amacrine cells: 206.3;Retinal bipolar cells: 464.8;Schwann cells: 251.1;Somatotrophs: 421.4;Thyrotrophs: 845.5" "Cell type enhanced" "Detected in many" "hippocampal CA1-3: 1854.7;hippocampal dentate gyrus: 2450.7" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 4.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 4.1;Neuroblastoma: 3.0" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal cortex cells, Breast - Breast myoepithelial cells, Colon - Enteric glia cells, Pituitary gland - Thyrotropes" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "hippocampal formation: 68.3" "HPA065593, HPA070354" Uncertain Approved Vesicles "Intracellular and membrane" Enzyme NA Yes 15000 "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 35: Neurons - Synaptic function & neurogenesis" Vesicles "HPA065593: , HPA070354: " "unprognostic (1.04e-1)" "unprognostic (1.15e-1)" "unprognostic (3.71e-1)" "unprognostic (1.98e-1)" "unprognostic (7.45e-3)" "unprognostic (3.35e-1)" "unprognostic (9.89e-3)" "unprognostic (7.26e-3)" "unprognostic (2.62e-1)" "unprognostic (2.34e-2)" "unprognostic (2.86e-2)" "unprognostic (3.92e-2)" "unprognostic (6.94e-2)" "unprognostic (2.68e-2)" "unprognostic (1.08e-1)" ST6GALNAC6 "SIAT7F, ST6GALNACVI" ENSG00000160408 "ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6" Q969X2 9 127885321-127905408 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 11.6;Bergmann glia: 15.2;Brain excitatory neurons: 14.3;Brain inhibitory neurons: 11.4;Choroid plexus epithelial cells: 4.4;Ependymal cells: 15.8;Microglia: 10.7;Oligodendrocyte progenitor cells: 6.1;Oligodendrocytes: 3.8;Other brain neurons: 11.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 5 "NK-cells: 23.7;T-cells: 25.6" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Lung - Fibroblasts_1, Minor Salivary Gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018890, HPA072757" Approved Approved Cytosol "Intracellular and membrane" Enzyme NA NA "Cluster 1: T-cells - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 98: Neurons - Neurotransmission & signaling" 3 Cytosol "HPA018890: , HPA072757: " "unprognostic (2.30e-2)" "unprognostic (8.75e-2)" "unprognostic (2.42e-1)" "unprognostic (2.19e-1)" "unprognostic (1.83e-1)" "unprognostic (2.21e-2)" "unprognostic (8.78e-2)" "unprognostic (2.14e-1)" "unprognostic (5.84e-2)" "unprognostic (8.62e-2)" "validated prognostic favorable (8.54e-5)" "validated prognostic favorable (4.36e-4)" "unprognostic (2.68e-2)" "unprognostic (2.60e-1)" "unprognostic (6.51e-2)" "unprognostic (1.34e-2)" "unprognostic (1.86e-1)" "unprognostic (3.42e-3)" "unprognostic (1.16e-1)" "unprognostic (1.73e-3)" "unprognostic (4.93e-2)" "unprognostic (6.09e-3)" "unprognostic (5.37e-2)" "unprognostic (9.48e-2)" "unprognostic (1.51e-1)" "potential prognostic unfavorable (3.04e-4)" "unprognostic (1.78e-1)" "potential prognostic unfavorable (8.87e-4)" "unprognostic (1.18e-1)" "unprognostic (6.96e-2)" "unprognostic (9.44e-2)" ST7 "ETS7q, FAM4A, FAM4A1, HELG, RAY1, SEN4, TSG7" ENSG00000004866 "Suppression of tumorigenicity 7" Q9NRC1 7 116953238-117230176 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 182.4;Proximal tubule cells: 355.5;Renal collecting duct intercalated cells: 300.8;Renal connecting tubule cells: 208.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Stomach - Chief cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038325, HPA038326" Approved Supported Nucleoplasm,Cytosol No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 22: Epididymis - Mixed function" "Cluster 35: Non-specific - DNA binding" "Cluster 39: Non-specific - Transcription" "Cluster 88: Proximal tubular cells - Transmembrane transport" 26 Nucleoplasm Cytosol "HPA038325: , HPA038326: " "unprognostic (1.57e-1)" "unprognostic (1.37e-1)" "unprognostic (9.76e-3)" "unprognostic (3.00e-1)" "unprognostic (2.12e-1)" "unprognostic (4.59e-3)" "unprognostic (8.58e-2)" "potential prognostic favorable (1.11e-4)" "unprognostic (1.87e-1)" "unprognostic (9.79e-3)" "potential prognostic favorable (2.23e-6)" "unprognostic (3.06e-3)" "unprognostic (1.57e-2)" "unprognostic (1.55e-2)" "unprognostic (4.81e-2)" "unprognostic (9.92e-3)" "unprognostic (2.53e-1)" "unprognostic (8.79e-2)" "unprognostic (1.19e-1)" "unprognostic (2.01e-2)" "unprognostic (3.49e-2)" "unprognostic (6.48e-2)" "unprognostic (1.78e-1)" "unprognostic (6.48e-2)" "unprognostic (3.48e-2)" "unprognostic (2.47e-1)" "unprognostic (1.19e-1)" "unprognostic (2.71e-1)" "unprognostic (1.64e-1)" "unprognostic (3.23e-2)" "unprognostic (2.66e-1)" ST7L "FAM4B, FLJ20284, ST7R, STLR" ENSG00000007341 "Suppression of tumorigenicity 7 like" Q8TDW4 1 112523514-112620825 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "testis: 33.7" "Cell type enhanced" "Detected in all" "Early spermatids: 222.7;Late primary spermatocytes: 218.8;Late spermatids: 529.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042324, HPA075418" Uncertain Approved Centrosome NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 57: Testis - Spermatogenesis" "Cluster 31: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" Centrosome "HPA042324: , HPA075418: " "unprognostic (2.21e-1)" "unprognostic (3.56e-1)" "unprognostic (1.81e-1)" "unprognostic (2.74e-3)" "unprognostic (2.06e-2)" "unprognostic (1.78e-1)" "unprognostic (2.00e-2)" "unprognostic (9.18e-2)" "unprognostic (3.14e-2)" "unprognostic (2.03e-1)" "unprognostic (8.65e-3)" "unprognostic (4.90e-2)" "unprognostic (2.44e-1)" "unprognostic (2.93e-3)" "unprognostic (5.59e-2)" "unprognostic (1.39e-1)" "unprognostic (7.48e-2)" "unprognostic (4.59e-2)" "unprognostic (1.76e-1)" "unprognostic (9.05e-2)" "unprognostic (2.87e-1)" "unprognostic (1.88e-1)" "unprognostic (1.11e-1)" "unprognostic (3.58e-1)" "unprognostic (9.09e-2)" "unprognostic (1.09e-1)" "potential prognostic unfavorable (6.91e-4)" "unprognostic (3.31e-2)" "unprognostic (2.98e-1)" "unprognostic (1.18e-2)" "unprognostic (4.24e-2)" ST8SIA1 "SIAT8, SIAT8A" ENSG00000111728 "ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1" Q92185 12 22063773-22437041 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 142.6;Astrocytes: 161.7;Bergmann glia: 486.0;Brain excitatory neurons: 138.5;Ependymal cells: 397.8;Mast cells: 217.5;Müller glia: 121.8;Myosatellite cells: 267.0;Oligodendrocyte progenitor cells: 336.0;Prostatic glandular cells: 140.9;Retinal ganglion cells: 146.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 7.0;Skin Cutaneous Melanoma (TCGA): 6.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Neuroblastoma: 4.3;skin cancer: 10.6" "Prostate - Smooth muscle cells, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026775 Approved NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 44: Non-specific - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 58: Mast cells - Allergic inflammatory responses" 7 "HPA026775: " "unprognostic (1.08e-1)" "unprognostic (6.36e-3)" "unprognostic (2.42e-2)" "unprognostic (2.30e-1)" "unprognostic (4.78e-2)" "unprognostic (1.38e-1)" "unprognostic (1.73e-1)" "unprognostic (5.51e-2)" "unprognostic (3.40e-1)" "unprognostic (2.86e-1)" "unprognostic (3.39e-1)" "unprognostic (4.19e-2)" "unprognostic (1.71e-2)" "unprognostic (5.99e-3)" "unprognostic (3.07e-1)" "unprognostic (2.72e-1)" ST8SIA2 "HsT19690, SIAT8B, ST8SIA-II, STX" ENSG00000140557 "ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2" Q92186 15 92393881-92468728 "Predicted secreted proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 3.6;lymphoid tissue: 1.7" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 9.1;Brain inhibitory neurons: 6.5;Breast myoepithelial cells: 4.3;Cardiomyocytes: 4.7;Epididymal basal cells: 4.8;Epididymal principal cells: 4.3;Müller glia: 5.1;Oocytes: 4.6;Other brain neurons: 9.3;Pituitary stem cells: 6.4;Retinal amacrine cells: 9.9;Retinal ganglion cells: 3.9;Thymic myoid cells: 4.1" "Cell type enhanced" "Detected in many" "lower rhombic lip: 106.6" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "pons: 18.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Myeloma: 7.8;Neuroblastoma: 18.3" "Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Skeletal muscle - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA054518, HPA057819" Approved Supported "Nucleoplasm,Golgi apparatus,Cytosol" "Secreted - unknown location" Enzyme NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 7 "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA054518: , HPA057819: " "unprognostic (2.28e-1)" "unprognostic (2.80e-2)" "unprognostic (1.17e-1)" "unprognostic (3.60e-3)" "unprognostic (1.91e-1)" "unprognostic (6.28e-2)" ST8SIA3 SIAT8C ENSG00000177511 "ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3" O43173 18 57352557-57371731 "Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 23.5;pituitary gland: 9.0;retina: 7.0" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 71.3;Brain inhibitory neurons: 110.9;Corticotrophs: 99.7;Gonadotrophs: 34.5;Lactotrophs: 46.9;Oligodendrocyte progenitor cells: 26.2;Other brain neurons: 59.9;Pancreatic islet cells: 60.4;Retinal amacrine cells: 25.9;Retinal bipolar cells: 25.2;Retinal horizontal cells: 68.1;Somatotrophs: 59.6;Thyrotrophs: 63.8" "Cell type enhanced" "Detected in many" "medium spiny neuron: 228.0" "Group enriched" "Detected in some" 10 "Glioblastoma Multiforme (TCGA): 1.7;Pancreatic Adenocarcinoma (TCGA): 3.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 9.4;thyroid cancer: 4.1" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Stomach - Gastric enteroendocrine cells, Thyroid gland - Parafollicular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063398, HPA066783" Enhanced Supported "Golgi apparatus" No NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" 8 "Golgi apparatus" "HPA063398: , HPA066783: " "unprognostic (1.94e-1)" "potential prognostic favorable (7.23e-4)" "unprognostic (1.49e-2)" "unprognostic (8.43e-2)" ST8SIA4 "PST, PST1, SIAT8D" ENSG00000113532 "ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4" Q92187 5 100806933-100903282 "Metabolic proteins, Predicted secreted proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 13.2;placenta: 10.5" "Cell type enhanced" "Detected in many" "B-cells: 171.1;cDC: 356.7;Kupffer cells: 239.8;Macrophages: 195.4;Microglia: 304.1;monocytes: 262.8;Neutrophil progenitors: 204.3;Neutrophils: 717.5;NK-cells: 131.0;Plasma cells: 192.0;Thymocytes: 171.1" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 415.1;leukocyte: 253.2;MGE interneuron: 224.1" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 15.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 91.9" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 10.5;lymphoma: 14.1;Myeloma: 17.3" "Adrenal gland - Macrophages, Breast - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA036437, HPA051126, HPA053995" Approved Supported "Golgi apparatus" "Secreted - unknown location" Enzyme NA NA 580000 "Cluster 35: Neutrophils - Protein binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 3 "Golgi apparatus" "HPA036437: , HPA051126: , HPA053995: " "unprognostic (1.77e-1)" "unprognostic (2.88e-1)" "unprognostic (5.68e-2)" "unprognostic (9.05e-2)" "unprognostic (1.27e-1)" "unprognostic (3.23e-1)" "unprognostic (2.30e-3)" "unprognostic (8.92e-2)" "unprognostic (1.34e-2)" "unprognostic (1.42e-1)" "potential prognostic favorable (3.79e-5)" "unprognostic (2.49e-2)" "unprognostic (4.16e-3)" "unprognostic (4.86e-2)" "unprognostic (2.56e-1)" "unprognostic (6.54e-2)" "unprognostic (4.27e-2)" "unprognostic (4.60e-2)" "unprognostic (9.41e-2)" "unprognostic (1.45e-2)" "unprognostic (1.98e-1)" "unprognostic (4.41e-1)" "unprognostic (1.05e-2)" "unprognostic (3.44e-1)" "unprognostic (6.03e-2)" "unprognostic (1.64e-1)" "unprognostic (1.91e-1)" "unprognostic (4.73e-2)" "unprognostic (7.26e-3)" "unprognostic (9.41e-2)" "unprognostic (2.34e-1)" ST8SIA5 SIAT8E ENSG00000101638 "ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5" O15466 18 46667821-46759257 "Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "adrenal gland: 5.9;brain: 23.2;parathyroid gland: 5.8" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 84.4;Brain excitatory neurons: 132.8;Brain inhibitory neurons: 76.6;Cardiomyocytes: 107.9;Gonadotrophs: 32.0;Myonuclei: 32.7;Oligodendrocyte progenitor cells: 52.4;Other brain neurons: 29.7;Renal collecting duct intercalated cells: 36.7;Retinal amacrine cells: 47.5" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in some" 7 "Glioblastoma Multiforme (TCGA): 5.4;Kidney Chromophobe (TCGA): 6.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 7.7" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043813, HPA046771" Approved Approved "Plasma membrane,Midbody" Yes NA 30000 "Cluster 27: Cerebellum - Synaptic function" "Cluster 37: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 35: Neurons - Synaptic function & neurogenesis" 29 "Plasma membrane, Midbody" "HPA043813: , HPA046771: " "unprognostic (1.16e-1)" "unprognostic (7.40e-2)" "unprognostic (7.97e-2)" "potential prognostic favorable (6.59e-4)" ST8SIA6 SIAT8F ENSG00000148488 "ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6" P61647 10 17315421-17454595 "Predicted intracellular proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.7;breast: 4.9;lung: 5.6" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 149.5;Erythrocyte progenitors: 133.0;Hematopoietic stem cells: 616.2;Mast cells: 206.2;Megakaryocyte progenitors: 315.1;Megakaryocyte-Erythroid progenitors: 601.1;Melanocytes: 268.7;NK-cells: 107.3;Respiratory ionocytes: 182.9;Vascular endothelial cells: 157.5" "Cell type enriched" "Detected in many" 5 "endothelial cell: 891.3" "Cancer enhanced" "Detected in some" "Breast Invasive Carcinoma (TCGA): 7.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 5 "breast cancer: 1.9;Leukemia: 7.1;Rhabdoid: 2.7" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Breast - Breast glandular cells, Liver - Vascular endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA011635, HPA072708" Uncertain Approved "Endoplasmic reticulum" "Intracellular and membrane" Enzyme NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 104: Brain endothelial cells - Blood brain barrier" "Endoplasmic reticulum" "HPA011635: , HPA072708: " "unprognostic (1.13e-2)" "unprognostic (1.65e-1)" "unprognostic (6.78e-3)" "unprognostic (5.43e-2)" "unprognostic (6.68e-2)" "unprognostic (2.61e-1)" "potential prognostic favorable (7.11e-4)" "unprognostic (1.25e-3)" "unprognostic (3.48e-1)" "unprognostic (8.08e-2)" "potential prognostic favorable (6.26e-4)" "unprognostic (1.32e-1)" "unprognostic (3.32e-1)" STAB1 "CLEVER-1, FEEL-1, FELE-1, FEX1, KIAA0246, SCARH2, STAB-1" ENSG00000010327 "Stabilin 1" Q9NY15 3 52495338-52524495 "Predicted membrane proteins, Transporters" "Inflammatory response" Receptor "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 428.0" "Cell type enhanced" "Detected in many" "Hofbauer cells: 295.1;Kupffer cells: 59.4;Lymphatic endothelial cells: 73.7;Macrophages: 341.7;Microglia: 53.2;monocytes: 173.1;Vascular endothelial cells: 69.9" "Cell type enriched" "Detected in some" 4 "central nervous system macrophage: 88.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 59 "classical monocyte: 9.5;intermediate monocyte: 5.7;myeloid DC: 2.5" "Group enriched" "Detected in many" 60 "dendritic cells: 2.5;monocytes: 9.5" "Cancer enriched" "Detected in single" 65 "Leukemia: 14.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005434 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 14000000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 5: Spleen - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 2 Cytosol "Nucleoplasm, Plasma membrane" "HPA005434: " "unprognostic (8.43e-3)" "unprognostic (1.38e-1)" "unprognostic (1.32e-1)" "unprognostic (1.38e-1)" "unprognostic (8.95e-2)" "unprognostic (3.71e-2)" "unprognostic (2.52e-2)" "unprognostic (2.28e-2)" "unprognostic (2.41e-1)" "unprognostic (5.83e-2)" "potential prognostic unfavorable (1.15e-5)" "unprognostic (1.80e-2)" "unprognostic (1.49e-1)" "potential prognostic unfavorable (7.13e-4)" "potential prognostic favorable (8.93e-4)" "unprognostic (5.75e-2)" "unprognostic (2.24e-3)" "unprognostic (1.26e-1)" "unprognostic (5.00e-1)" "unprognostic (3.75e-2)" "unprognostic (1.24e-1)" "unprognostic (1.68e-2)" "unprognostic (1.01e-1)" "unprognostic (9.81e-2)" "unprognostic (5.20e-1)" "unprognostic (2.11e-3)" "unprognostic (3.83e-1)" "unprognostic (2.50e-2)" "unprognostic (3.42e-2)" "unprognostic (1.20e-1)" "unprognostic (3.69e-1)" STAB2 "DKFZP434E0321, FEEL-2, FELL, HARE, SCARH1, STAB-2" ENSG00000136011 "Stabilin 2" Q8WWQ8 12 103587273-103766719 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 63.4" "Cell type enriched" "Detected in many" 7 "Lymphatic endothelial cells: 229.0" "Cell type enhanced" "Detected in many" "hippocampal CA4: 16.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Smooth muscle cells, Liver - Sinusoid Endothelial cells, Pituitary gland - Gonadotropes, Stomach - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Fibroblasts" "Not detected" "Not detected" "Not detected" "Not detected" "HPA026871, HPA072699" Enhanced Supported Cytosol NA NA 760000 "Cluster 5: Spleen - Immune response" "Cluster 51: Neurons - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 1 Cytosol "HPA026871: , HPA072699: " "unprognostic (1.06e-1)" "unprognostic (7.67e-2)" "potential prognostic unfavorable (2.98e-4)" "unprognostic (2.89e-2)" "unprognostic (9.48e-3)" "unprognostic (2.44e-1)" STAC STAC1 ENSG00000144681 "SH3 and cysteine rich domain" Q99469 3 36380503-36548007 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 14.0" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 202.1;Breast lactating cells: 101.3;Choroid plexus epithelial cells: 181.0;Corticotrophs: 502.6;Distal convoluted tubule cells: 110.2;Innate lymphoid cells: 146.4;Megakaryocyte progenitors: 87.1;Müller glia: 170.0;Other brain neurons: 74.7;Platelets: 99.1;Renal connecting tubule cells: 84.7" "Cell type enhanced" "Detected in many" "mammillary body: 274.6;pericyte: 188.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "eosinophil: 1.5;NK-cell: 1.3;T-reg: 1.5" "Group enriched" "Detected in many" 5 "granulocytes: 1.5;NK-cells: 1.3;T-cells: 1.5" "Cancer enhanced" "Detected in many" "Neuroblastoma: 35.6" "Liver - Hepatic stellate cells, Minor Salivary Gland - Endothelial cells, Prostate - Smooth muscle cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA035143 Uncertain Uncertain "Nucleoplasm,Plasma membrane" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 44: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 109: Neurons - Neuronal signaling" 19 "Nucleoplasm, Plasma membrane" "HPA035143: " "unprognostic (2.45e-3)" "unprognostic (4.13e-2)" "unprognostic (1.57e-1)" "unprognostic (4.61e-2)" "unprognostic (7.24e-2)" "unprognostic (1.28e-3)" "unprognostic (1.69e-2)" "potential prognostic unfavorable (6.54e-4)" "unprognostic (1.33e-3)" "unprognostic (4.05e-2)" "potential prognostic unfavorable (3.44e-4)" "unprognostic (2.14e-2)" "unprognostic (1.75e-1)" "unprognostic (1.33e-1)" "unprognostic (4.59e-3)" "potential prognostic unfavorable (1.10e-4)" "unprognostic (4.81e-2)" "unprognostic (1.32e-3)" "unprognostic (2.95e-2)" "unprognostic (2.53e-2)" "potential prognostic unfavorable (4.85e-4)" "unprognostic (9.23e-2)" "unprognostic (2.10e-1)" STAC2 24b2 ENSG00000141750 "SH3 and cysteine rich domain 2" Q6ZMT1 17 39210541-39225945 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 78.5;breast: 51.6;retina: 112.3;skin 1: 49.0" "Cell type enriched" "Detected in many" 4 "Müller glia: 960.2" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in many" 4 "Kidney Chromophobe (TCGA): 76.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 8.0;cervical cancer: 5.5" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076925 Approved Cytosol NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 11: Muller glia cells - Retinal homeostasis" 3 Cytosol "HPA076925: " "unprognostic (1.38e-3)" "unprognostic (2.03e-1)" "unprognostic (1.47e-3)" "unprognostic (2.71e-2)" "unprognostic (3.57e-1)" "unprognostic (5.34e-2)" "unprognostic (3.30e-1)" "unprognostic (1.85e-2)" "unprognostic (2.31e-2)" "unprognostic (2.99e-3)" "unprognostic (4.11e-2)" "potential prognostic unfavorable (3.93e-4)" "unprognostic (3.21e-1)" "unprognostic (2.55e-2)" "unprognostic (2.25e-1)" "unprognostic (1.41e-1)" "unprognostic (9.36e-2)" STAC3 MGC2793 ENSG00000185482 "SH3 and cysteine rich domain 3" Q96MF2 12 57243453-57251188 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 38 "skeletal muscle: 2168.8;tongue: 1091.4" "Group enriched" "Detected in many" 5 "Myonuclei: 358.7;Thymic myoid cells: 303.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Head and Neck Squamous Cell Carcinoma (TCGA): 24.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 5.8" "Group enriched" "Detected in many" 6 "dendritic cells: 3.6;monocytes: 5.8" "Cancer enriched" "Detected in many" 7 "Sarcoma: 168.2" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Lung - Macrophages, Spleen - Macrophages, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" "HPA039285, HPA039527" Enhanced Nucleoplasm,Cytosol NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 48: Non-specific - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 34 Nucleoplasm Cytosol "HPA039285: , HPA039527: " "unprognostic (2.18e-2)" "unprognostic (2.23e-1)" "unprognostic (2.87e-2)" "unprognostic (6.41e-2)" "unprognostic (1.80e-2)" "unprognostic (7.85e-2)" "unprognostic (1.46e-2)" "unprognostic (1.26e-2)" "unprognostic (2.64e-2)" "unprognostic (5.70e-2)" "potential prognostic unfavorable (1.15e-5)" "unprognostic (4.87e-2)" "potential prognostic favorable (4.63e-5)" "unprognostic (2.68e-2)" "unprognostic (3.11e-2)" "unprognostic (3.37e-2)" "unprognostic (4.79e-2)" "unprognostic (1.32e-1)" "unprognostic (1.76e-1)" "unprognostic (2.30e-1)" "unprognostic (2.34e-2)" "unprognostic (3.39e-1)" "unprognostic (1.15e-1)" "unprognostic (1.17e-1)" "unprognostic (3.38e-2)" "unprognostic (1.20e-1)" "unprognostic (2.83e-1)" "unprognostic (6.97e-2)" "unprognostic (3.39e-1)" "unprognostic (4.22e-2)" "unprognostic (2.19e-1)" STAG1 "SA-1, SA1, SCC3A" ENSG00000118007 "Stromal antigen 1" Q8WVM7 3 136336236-136752403 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 1432.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035015, HPA058653" Supported Supported "Nucleoplasm,Nuclear bodies,Primary cilium" No No "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 24: Neutrophils - Innate immunity signal integration" 32 Nucleoplasm "Nuclear bodies, Primary cilium" "HPA035015: , HPA058653: " "unprognostic (1.06e-3)" "unprognostic (1.04e-1)" "unprognostic (4.99e-2)" "unprognostic (5.22e-2)" "unprognostic (1.48e-1)" "unprognostic (3.50e-2)" "unprognostic (6.39e-2)" "unprognostic (5.44e-2)" "unprognostic (1.57e-1)" "unprognostic (6.20e-3)" "validated prognostic favorable (9.84e-6)" "validated prognostic favorable (7.03e-4)" "unprognostic (2.03e-1)" "unprognostic (1.51e-2)" "unprognostic (3.19e-2)" "unprognostic (1.13e-2)" "unprognostic (1.64e-1)" "unprognostic (2.57e-1)" "unprognostic (1.17e-1)" "unprognostic (7.60e-3)" "unprognostic (2.28e-3)" "unprognostic (1.01e-2)" "unprognostic (1.14e-3)" "unprognostic (1.33e-1)" "unprognostic (4.90e-2)" "unprognostic (9.72e-3)" "unprognostic (2.04e-1)" "unprognostic (2.07e-1)" "unprognostic (1.52e-1)" "unprognostic (6.57e-2)" "unprognostic (1.83e-1)" STAG2 "SA-2, SA2, SCC3B" ENSG00000101972 "Stromal antigen 2" Q8N3U4 X 123960212-124422664 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Meiosis, Mitosis" "Cancer-related genes, Disease variant, Holoprosencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 617.6;Neutrophils: 932.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002857 Supported Supported "Nucleoplasm,Nucleoli,Nucleoli fibrillar center" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 80: Thymus - Adaptive immune response" "Cluster 55: Non-specific - Transcription" "Cluster 36: Non-specific - mRNA processing" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 55 "Nucleoplasm, Nucleoli, Nucleoli fibrillar center" "HPA002857: " "unprognostic (1.39e-1)" "unprognostic (3.30e-2)" "unprognostic (1.04e-1)" "unprognostic (1.89e-1)" "unprognostic (6.21e-2)" "unprognostic (2.18e-2)" "unprognostic (4.56e-2)" "unprognostic (1.13e-2)" "unprognostic (1.94e-1)" "unprognostic (1.10e-2)" "potential prognostic favorable (1.30e-6)" "unprognostic (1.27e-2)" "unprognostic (1.04e-1)" "unprognostic (2.42e-2)" "unprognostic (9.77e-3)" "unprognostic (2.29e-1)" "unprognostic (1.47e-2)" "unprognostic (4.06e-2)" "unprognostic (1.55e-1)" "unprognostic (1.83e-1)" "unprognostic (1.15e-2)" "unprognostic (1.61e-1)" "unprognostic (8.14e-3)" "unprognostic (1.80e-1)" "unprognostic (7.60e-3)" "unprognostic (1.01e-1)" "unprognostic (7.29e-2)" "unprognostic (8.63e-2)" "unprognostic (8.67e-2)" "unprognostic (6.64e-2)" "unprognostic (2.97e-1)" STAG3 ENSG00000066923 "Stromal antigen 3" Q9UJ98 7 100177563-100221488 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Chromosome partition, Meiosis" "Disease variant, Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 46 "testis: 49.8" "Cell type enriched" "Detected in many" 5 "Oocytes: 1340.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 3.5" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA049106, HPA058330" Enhanced Supported Nucleoplasm,Nucleoli NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 57: Testis - Spermatogenesis" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 41: Oocytes - Oogenesis" 1 Nucleoli Nucleoplasm "HPA049106: , HPA058330: " "unprognostic (1.93e-2)" "unprognostic (1.82e-2)" "unprognostic (3.69e-3)" "potential prognostic favorable (2.55e-4)" "unprognostic (1.35e-1)" "unprognostic (2.52e-1)" "unprognostic (2.24e-2)" "potential prognostic unfavorable (7.82e-4)" "unprognostic (1.63e-1)" "unprognostic (2.55e-2)" STAM STAM1 ENSG00000136738 "Signal transducing adaptor molecule" Q92783 10 17644151-17716824 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 50.1" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 210.9;Innate lymphoid cells: 238.2;Neutrophil progenitors: 214.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "T-reg: 76.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034399, HPA043882, HPA060658" Supported Supported Vesicles NA NA 370000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 15: Bone marrow - Innate immune response" "Cluster 34: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 9: T-cells - Adaptive immunity: Regulation" 38 Vesicles "CAB034399: , HPA043882: , HPA060658: " "unprognostic (5.91e-2)" "unprognostic (3.19e-2)" "unprognostic (3.35e-2)" "unprognostic (1.43e-1)" "unprognostic (4.03e-1)" "unprognostic (2.10e-2)" "unprognostic (9.14e-2)" "potential prognostic favorable (6.32e-5)" "unprognostic (4.72e-2)" "unprognostic (2.14e-2)" "potential prognostic favorable (6.30e-7)" "unprognostic (3.31e-2)" "unprognostic (5.48e-3)" "potential prognostic unfavorable (2.86e-6)" "unprognostic (4.07e-2)" "unprognostic (1.41e-2)" "unprognostic (2.46e-1)" "unprognostic (2.53e-1)" "unprognostic (2.57e-1)" "unprognostic (2.22e-1)" "unprognostic (2.65e-2)" "unprognostic (1.20e-2)" "potential prognostic unfavorable (6.22e-4)" "unprognostic (4.53e-2)" "unprognostic (8.65e-2)" "unprognostic (6.00e-2)" "unprognostic (5.65e-2)" "unprognostic (2.89e-1)" "unprognostic (2.95e-1)" "unprognostic (1.54e-1)" "unprognostic (6.25e-2)" STAM2 Hbp ENSG00000115145 "Signal transducing adaptor molecule 2" O75886 2 152116801-152175763 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 16.9" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035528, HPA035529" Enhanced Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 32: Basophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 7: Non-specific - Transcription" 72 Vesicles "Nucleoplasm, Cytosol" "HPA035528: , HPA035529: " "unprognostic (2.97e-3)" "unprognostic (2.89e-2)" "unprognostic (1.81e-2)" "unprognostic (3.14e-2)" "unprognostic (1.39e-1)" "unprognostic (1.90e-1)" "unprognostic (2.45e-1)" "unprognostic (4.22e-1)" "unprognostic (5.04e-2)" "unprognostic (2.95e-2)" "validated prognostic favorable (6.46e-7)" "validated prognostic favorable (2.98e-4)" "unprognostic (1.07e-1)" "unprognostic (2.87e-2)" "unprognostic (2.30e-1)" "unprognostic (6.76e-2)" "unprognostic (1.48e-1)" "unprognostic (7.26e-2)" "unprognostic (2.33e-1)" "unprognostic (1.11e-1)" "unprognostic (2.39e-3)" "unprognostic (4.76e-2)" "unprognostic (3.05e-1)" "unprognostic (1.89e-1)" "unprognostic (1.35e-1)" "unprognostic (1.82e-1)" "unprognostic (3.03e-2)" "unprognostic (7.39e-2)" "unprognostic (5.24e-1)" "unprognostic (6.88e-2)" "unprognostic (1.67e-1)" STAMBP AMSH ENSG00000124356 "STAM binding protein" O95630 2 73828916-73873659 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Metalloprotease, Protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 228.8;Late spermatids: 211.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035800, HPA035801" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 59 Nucleoplasm "Plasma membrane, Cytosol" "HPA035800: , HPA035801: " "unprognostic (1.01e-2)" "unprognostic (3.54e-2)" "unprognostic (5.43e-2)" "unprognostic (1.77e-2)" "unprognostic (4.14e-2)" "unprognostic (4.00e-1)" "unprognostic (3.62e-2)" "unprognostic (1.14e-2)" "unprognostic (2.44e-2)" "unprognostic (4.65e-2)" "potential prognostic favorable (7.87e-6)" "unprognostic (4.22e-1)" "unprognostic (1.38e-1)" "unprognostic (2.21e-2)" "potential prognostic unfavorable (3.43e-4)" "unprognostic (7.74e-3)" "unprognostic (1.41e-2)" "unprognostic (9.15e-2)" "unprognostic (1.59e-1)" "unprognostic (5.39e-2)" "unprognostic (2.76e-2)" "potential prognostic unfavorable (8.03e-4)" "unprognostic (2.47e-3)" "unprognostic (2.26e-1)" "unprognostic (3.54e-2)" "unprognostic (1.23e-1)" "unprognostic (6.75e-2)" "unprognostic (2.32e-1)" "unprognostic (2.92e-1)" "unprognostic (1.83e-1)" "unprognostic (9.13e-2)" STAMBPL1 "ALMalpha, AMSH-FP, AMSH-LP, bA399O19.2, FLJ31524, KIAA1373" ENSG00000138134 "STAM binding protein like 1" Q96FJ0 10 88879734-88975153 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 22.5" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 135.0;Late primary spermatocytes: 88.7;Microglia: 148.9;Pericytes: 95.2;Vascular smooth muscle cells: 338.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Breast - T-cells, Pituitary gland - Lactotropes, Skeletal muscle - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040202 Uncertain Approved "Plasma membrane" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 53: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 37 "Plasma membrane" "HPA040202: " "unprognostic (1.00e-1)" "unprognostic (1.76e-1)" "potential prognostic favorable (6.44e-6)" "unprognostic (2.02e-2)" "unprognostic (9.51e-2)" "unprognostic (1.36e-1)" "unprognostic (2.98e-1)" "unprognostic (1.46e-2)" "unprognostic (7.37e-2)" "unprognostic (2.17e-1)" "unprognostic (3.72e-3)" "unprognostic (4.09e-3)" "unprognostic (5.28e-3)" "unprognostic (3.00e-3)" "unprognostic (8.88e-2)" "unprognostic (1.68e-3)" "unprognostic (1.81e-2)" "unprognostic (3.03e-2)" "unprognostic (1.37e-3)" "unprognostic (3.13e-1)" "unprognostic (8.43e-2)" "unprognostic (1.49e-1)" "unprognostic (1.92e-2)" "unprognostic (6.49e-2)" "unprognostic (3.44e-3)" "unprognostic (8.03e-2)" "unprognostic (7.74e-2)" "unprognostic (4.94e-2)" "unprognostic (5.77e-3)" "unprognostic (1.32e-1)" "unprognostic (5.92e-2)" STAP1 "BRDG1, STAP-1" ENSG00000035720 "Signal transducing adaptor family member 1" Q9ULZ2 4 67558727-67607337 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "lymphoid tissue: 47.7" "Cell type enhanced" "Detected in some" "B-cells: 193.1;Epididymal clear cells: 616.5;Mast cells: 118.1;pDCs: 88.1;Plasma cells: 186.0;Renal collecting duct intercalated cells: 265.0;Respiratory ionocytes: 1206.5" "Cell type enriched" "Detected in some" 5 "leukocyte: 11.3" "Cancer enriched" "Detected in many" 30 "Kidney Chromophobe (TCGA): 188.8" "Region enhanced" "Detected in single" "hippocampal formation: 1.2" "Immune cell enhanced" "Detected in many" "memory B-cell: 88.5;naive B-cell: 108.3" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in some" 5 "lymphoma: 71.2" "Colon - Mast cells, Kidney - Intercalated cells, Minor Salivary Gland - Plasma cells, Spleen - B-cells (Spleen), Testis - Early spermatids" "Region enriched" "Detected in single" 5 "cerebellum: 2.3" "Low region specificity" "Detected in all" "HPA038094, HPA038529" Enhanced Supported "Nuclear bodies,Cytosol" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 29: Forebrain - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 8 "Nuclear bodies, Cytosol" "HPA038094: , HPA038529: " "unprognostic (6.93e-3)" "unprognostic (1.70e-1)" "unprognostic (1.00e-1)" "unprognostic (2.94e-1)" "unprognostic (2.40e-1)" "unprognostic (5.72e-2)" "unprognostic (3.27e-3)" "potential prognostic favorable (8.76e-5)" "unprognostic (3.17e-2)" "unprognostic (4.63e-3)" "unprognostic (1.53e-1)" "unprognostic (4.28e-1)" "unprognostic (1.15e-2)" "unprognostic (1.95e-2)" "unprognostic (5.22e-3)" "unprognostic (1.14e-2)" STAP2 "BKS, STAP-2" ENSG00000178078 "Signal transducing adaptor family member 2" Q9UGK3 19 4324043-4342786 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 89.7" "Cell type enhanced" "Detected in many" "Colonocytes: 356.0;Enteric stem cells: 127.4;Enteric transient amplifying cells: 177.8;Enterocytes: 425.4;Esophageal apical cells: 378.7;Esophageal basal cells: 160.2;Esophageal suprabasal cells: 290.4;Goblet cells: 151.1;Suprabasal keratinocytes: 129.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 8.0" "Group enriched" "Detected in many" 6 "dendritic cells: 2.2;NK-cells: 8.0;T-cells: 2.5" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Skin - Keratinocyte (other)" "Region enriched" "Detected in many" 13 "cerebellum: 20.5" "Low region specificity" "Detected in some" "HPA002375, HPA027761" Approved NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 17: Intestine - Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 19 "HPA002375: , HPA027761: " "unprognostic (1.88e-3)" "unprognostic (5.62e-2)" "unprognostic (7.01e-2)" "unprognostic (8.64e-3)" "unprognostic (5.27e-2)" "unprognostic (1.14e-1)" "unprognostic (4.09e-2)" "unprognostic (7.88e-2)" "unprognostic (3.53e-3)" "unprognostic (8.50e-2)" "potential prognostic favorable (6.59e-5)" "unprognostic (1.05e-1)" "potential prognostic favorable (2.27e-4)" "unprognostic (1.76e-1)" "unprognostic (2.85e-1)" "unprognostic (4.75e-2)" "unprognostic (3.77e-2)" "unprognostic (4.84e-2)" "unprognostic (2.03e-1)" "unprognostic (4.42e-2)" "unprognostic (1.08e-1)" "unprognostic (1.94e-2)" "unprognostic (2.42e-1)" "unprognostic (2.66e-1)" "unprognostic (7.75e-2)" "unprognostic (4.90e-1)" "unprognostic (8.04e-2)" "unprognostic (2.73e-2)" "unprognostic (6.46e-2)" "unprognostic (6.45e-2)" "unprognostic (1.32e-2)" STAR STARD1 ENSG00000147465 "Steroidogenic acute regulatory protein" P49675 8 38142700-38150992 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Steroidogenesis, Transport" "Congenital adrenal hyperplasia, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "adrenal gland: 3979.9" "Group enriched" "Detected in many" 12 "Adrenal cortex cells: 1876.3;Ovarian stromal cells: 606.9" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Lung Squamous Cell Carcinoma (TCGA): 5.6;Testicular Germ Cell Tumor (TCGA): 7.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "basophil: 2.4" "Lineage enriched" "Detected in single" 10 "granulocytes: 2.4" "Cancer enriched" "Detected in some" 13 "Leukemia: 21.6" "Adrenal gland - Adrenal cortex cells, Skin - Keratinocyte (other), Testis - Leydig cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA023644, HPA027318, CAB032598" Enhanced NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 1: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 18: Adrenal cortex cells - Steroidogensis" 8 "CAB032598: , HPA023644: , HPA027318: " "unprognostic (2.44e-3)" "unprognostic (2.15e-1)" "unprognostic (3.56e-2)" "potential prognostic favorable (2.56e-4)" "unprognostic (2.68e-2)" "unprognostic (1.15e-1)" "unprognostic (8.06e-2)" "unprognostic (1.99e-2)" "unprognostic (9.13e-2)" "unprognostic (1.49e-1)" STARD10 "CGI-52, NY-CO-28, PCTP2, SDCCAG28" ENSG00000214530 "StAR related lipid transfer domain containing 10" Q9Y365 11 72754729-72794047 "Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 710.4" "Group enriched" "Detected in many" 4 "Late spermatids: 703.9;Parietal cells: 226.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 21.3" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "breast cancer: 373.2" "Breast - Breast glandular cells, Breast - Breast glandular cells, Liver - Hepatocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026661 Uncertain Supported Cytosol NA NA 35000 "Cluster 21: Neutrophils - Unknown function" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 37: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 3 Cytosol "HPA026661: " "unprognostic (1.60e-1)" "unprognostic (4.79e-2)" "unprognostic (1.21e-2)" "unprognostic (2.84e-1)" "unprognostic (1.26e-1)" "unprognostic (2.49e-1)" "unprognostic (6.17e-2)" "potential prognostic favorable (8.82e-5)" "unprognostic (1.37e-1)" "unprognostic (1.96e-1)" "validated prognostic favorable (2.62e-5)" "validated prognostic favorable (6.39e-4)" "unprognostic (9.65e-2)" "unprognostic (3.04e-2)" "unprognostic (9.97e-2)" "unprognostic (5.52e-2)" "unprognostic (8.78e-2)" "unprognostic (1.58e-1)" "unprognostic (5.09e-1)" "unprognostic (1.58e-1)" "unprognostic (7.29e-2)" "unprognostic (3.69e-1)" "unprognostic (9.80e-2)" "unprognostic (8.11e-2)" "unprognostic (1.07e-1)" "unprognostic (1.79e-3)" "unprognostic (8.41e-2)" "unprognostic (1.65e-1)" "unprognostic (2.80e-1)" "potential prognostic favorable (9.84e-4)" "unprognostic (1.86e-1)" STARD13 "ARHGAP37, DLC2, GT650, LINC00464" ENSG00000133121 "StAR related lipid transfer domain containing 13" Q9Y3M8 13 33103137-33350630 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 585.0;Bergmann glia: 826.7;Choroid plexus epithelial cells: 724.4;Macrophages: 562.0;Schwann cells: 1264.8" "Cell type enhanced" "Detected in all" "Bergmann glia: 866.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 30.8" "Prostate - Smooth muscle cells, Skin - Endothelial cells, Spleen - Endothelial cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039535, HPA058867" Supported Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 11: White matter - Signal transduction" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 5 "Golgi apparatus, Vesicles" Nucleoplasm "HPA039535: , HPA058867: " "unprognostic (2.34e-1)" "unprognostic (2.99e-1)" "unprognostic (1.06e-1)" "unprognostic (4.00e-2)" "unprognostic (5.02e-2)" "unprognostic (2.47e-1)" "unprognostic (3.75e-2)" "unprognostic (1.06e-1)" "unprognostic (1.37e-1)" "unprognostic (2.34e-1)" "validated prognostic favorable (9.47e-6)" "validated prognostic favorable (2.70e-5)" "unprognostic (1.80e-1)" "unprognostic (1.76e-1)" "unprognostic (1.69e-1)" "unprognostic (2.44e-1)" "unprognostic (1.23e-1)" "unprognostic (3.04e-2)" "unprognostic (1.92e-2)" "unprognostic (2.78e-3)" "unprognostic (3.35e-2)" "unprognostic (2.82e-2)" "unprognostic (1.14e-1)" "unprognostic (6.18e-2)" "unprognostic (4.88e-1)" "unprognostic (4.68e-2)" "unprognostic (6.17e-2)" "unprognostic (1.65e-1)" "unprognostic (1.12e-1)" "unprognostic (4.61e-2)" "unprognostic (9.99e-3)" STARD3 "es64, MLN64" ENSG00000131748 "StAR related lipid transfer domain containing 3" Q14849 17 39637090-39664201 "Cancer-related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Sertoli cells: 100.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017021, HPA024307, HPA073948" Uncertain Approved "Nucleoplasm,Endoplasmic reticulum,Vesicles" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 24: Non-specific - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 31 "Nucleoplasm, Vesicles" "Endoplasmic reticulum" "CAB017021: , HPA024307: , HPA073948: " "unprognostic (9.94e-2)" "unprognostic (3.94e-2)" "unprognostic (3.75e-2)" "unprognostic (1.07e-1)" "unprognostic (5.83e-2)" "unprognostic (2.01e-2)" "unprognostic (4.27e-2)" "unprognostic (1.63e-2)" "unprognostic (1.03e-2)" "unprognostic (9.37e-3)" "potential prognostic favorable (2.63e-6)" "unprognostic (2.09e-2)" "unprognostic (1.45e-1)" "unprognostic (2.31e-3)" "potential prognostic unfavorable (3.13e-4)" "unprognostic (6.49e-2)" "unprognostic (4.77e-2)" "unprognostic (9.56e-2)" "unprognostic (3.15e-1)" "unprognostic (3.50e-2)" "unprognostic (1.91e-1)" "unprognostic (2.44e-1)" "potential prognostic unfavorable (1.32e-4)" "unprognostic (1.46e-1)" "unprognostic (6.97e-2)" "unprognostic (2.32e-3)" "unprognostic (1.56e-1)" "unprognostic (1.16e-1)" "unprognostic (6.93e-2)" "unprognostic (1.79e-1)" "unprognostic (2.71e-1)" STARD3NL "MENTHO, MGC3251" ENSG00000010270 "STARD3 N-terminal like" O95772 7 38178245-38230670 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Skin - Endothelial cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019204 Enhanced Supported Vesicles NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 67: Non-specific - Unknown function" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 3 Vesicles "HPA019204: " "unprognostic (8.78e-3)" "unprognostic (7.10e-3)" "unprognostic (1.39e-2)" "unprognostic (2.75e-3)" "unprognostic (2.69e-1)" "unprognostic (8.31e-3)" "unprognostic (1.55e-2)" "potential prognostic unfavorable (9.54e-4)" "unprognostic (3.75e-3)" "unprognostic (1.84e-2)" "potential prognostic favorable (1.38e-7)" "unprognostic (6.40e-2)" "unprognostic (9.50e-2)" "potential prognostic unfavorable (7.29e-5)" "unprognostic (1.50e-2)" "unprognostic (2.25e-1)" "unprognostic (6.47e-2)" "unprognostic (3.93e-3)" "unprognostic (2.20e-2)" "unprognostic (3.47e-1)" "unprognostic (1.11e-1)" "unprognostic (2.28e-2)" "unprognostic (6.97e-3)" "unprognostic (6.66e-2)" "unprognostic (5.34e-2)" "unprognostic (2.43e-1)" "unprognostic (1.10e-1)" "unprognostic (6.01e-3)" "unprognostic (1.82e-1)" "unprognostic (6.41e-2)" "unprognostic (1.06e-1)" STARD4 ENSG00000164211 "StAR related lipid transfer domain containing 4" Q96DR4 5 111496033-111512590 "Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 65.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Pituitary gland - Thyrotropes, Skin - Outer root sheath cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046177, HPA048081" Approved Approved "Plasma membrane" NA Yes "Cluster 32: Basophils - Transcription" "Cluster 77: Intestine - Digestion" "Cluster 25: Non-specific - Transcription" "Cluster 55: Lymphoma - Immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 4 "Plasma membrane" "HPA046177: , HPA048081: " "unprognostic (4.14e-2)" "unprognostic (1.43e-1)" "unprognostic (1.35e-1)" "unprognostic (4.27e-2)" "unprognostic (1.21e-1)" "unprognostic (1.10e-1)" "unprognostic (2.47e-1)" "unprognostic (2.37e-2)" "unprognostic (1.49e-2)" "unprognostic (2.41e-3)" "unprognostic (1.17e-3)" "unprognostic (1.18e-1)" "potential prognostic unfavorable (9.10e-4)" "potential prognostic unfavorable (1.04e-4)" "unprognostic (1.06e-1)" "unprognostic (2.10e-2)" "unprognostic (6.92e-2)" "unprognostic (5.92e-2)" "unprognostic (1.53e-1)" "unprognostic (2.27e-1)" "unprognostic (2.58e-1)" "unprognostic (8.31e-2)" "potential prognostic unfavorable (2.26e-4)" "unprognostic (6.78e-2)" "unprognostic (4.93e-2)" "unprognostic (3.59e-3)" "unprognostic (8.81e-2)" "unprognostic (2.77e-2)" "unprognostic (3.72e-2)" "potential prognostic unfavorable (1.45e-4)" "unprognostic (1.74e-1)" STARD5 MGC10327 ENSG00000172345 "StAR related lipid transfer domain containing 5" Q9NSY2 15 81309053-81324183 "Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 49.7;Epicardial cells: 63.7;Esophageal apical cells: 44.3;Esophageal basal cells: 27.4;Esophageal suprabasal cells: 32.4;Goblet cells: 24.4;Hepatocytes: 25.1;Plasma cells: 39.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Myeloma: 4.5" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA040662 Approved Approved Vesicles,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 58: Skin - Keratinization" "Cluster 5: Non-specific - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 44: Plasma cells - Antibody production & secretion" Vesicles Cytosol "HPA040662: " "unprognostic (3.03e-2)" "unprognostic (8.15e-3)" "unprognostic (7.48e-3)" "unprognostic (4.10e-2)" "unprognostic (2.88e-1)" "unprognostic (1.40e-1)" "unprognostic (9.18e-2)" "unprognostic (1.93e-3)" "unprognostic (4.89e-3)" "unprognostic (8.19e-2)" "potential prognostic favorable (4.38e-6)" "unprognostic (2.91e-3)" "unprognostic (1.13e-1)" "unprognostic (2.56e-1)" "unprognostic (3.70e-1)" "potential prognostic favorable (5.90e-4)" "unprognostic (1.73e-1)" "unprognostic (2.50e-1)" "unprognostic (7.63e-2)" "unprognostic (3.39e-2)" "unprognostic (1.73e-1)" "unprognostic (2.80e-2)" "unprognostic (3.55e-2)" "unprognostic (1.97e-1)" STARD6 ENSG00000174448 "StAR related lipid transfer domain containing 6" P59095 18 54324358-54357964 "Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 16 "testis: 1.7" "Group enriched" "Detected in some" 8 "Early spermatids: 176.7;Late primary spermatocytes: 283.2;Late spermatids: 445.1" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 67: Testis - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" "unprognostic (3.90e-2)" STARD7 GTT1 ENSG00000084090 "StAR related lipid transfer domain containing 7" Q9NQZ5 2 96184859-96208827 "Essential proteins, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Thymic myoid cells: 221.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033965, HPA064958, HPA064978" Supported Approved Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 82: Dendritic cells - Antigen presentation" 2 Mitochondria "CAB033965: , HPA064958: , HPA064978: " "unprognostic (1.39e-1)" "unprognostic (1.29e-2)" "unprognostic (1.29e-1)" "unprognostic (1.80e-1)" "unprognostic (1.09e-1)" "unprognostic (1.10e-1)" "unprognostic (1.85e-1)" "unprognostic (6.24e-2)" "unprognostic (3.17e-1)" "unprognostic (2.50e-3)" "potential prognostic favorable (1.88e-8)" "unprognostic (5.31e-3)" "unprognostic (2.83e-2)" "unprognostic (2.47e-3)" "potential prognostic unfavorable (2.80e-6)" "unprognostic (4.61e-1)" "unprognostic (2.58e-1)" "unprognostic (1.25e-1)" "unprognostic (7.85e-3)" "unprognostic (1.55e-1)" "unprognostic (3.13e-2)" "unprognostic (3.01e-1)" "unprognostic (1.53e-2)" "unprognostic (4.31e-2)" "unprognostic (3.36e-1)" "unprognostic (1.23e-1)" "unprognostic (3.24e-1)" "unprognostic (1.13e-1)" "unprognostic (1.61e-1)" "unprognostic (3.30e-3)" "unprognostic (1.12e-1)" STARD8 "ARHGAP38, KIAA0189" ENSG00000130052 "StAR related lipid transfer domain containing 8" Q92502 X 68647666-68725842 "Metabolic proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "cDC: 19.8;Distal convoluted tubule cells: 26.9;Kupffer cells: 45.1;Loop of henle epithelial cells: 28.0;Lymphatic endothelial cells: 34.0;Macrophages: 24.6;monocytes: 29.5;Pericytes: 21.2;Platelets: 25.5;Proximal tubule cells: 22.3;Vascular endothelial cells: 35.6" "Cell type enhanced" "Detected in many" "endothelial cell: 78.0;fibroblast: 34.2;pericyte: 110.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 15 "classical monocyte: 1.6;intermediate monocyte: 3.2;myeloid DC: 3.4;non-classical monocyte: 4.8" "Group enriched" "Detected in many" 18 "dendritic cells: 3.4;monocytes: 4.8" "Cancer enhanced" "Detected in many" "Leukemia: 10.2" "Breast - Endothelial cells, Colon - Endothelial cells, Prostate - Fibroblasts, Stomach - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060788 Uncertain NA Yes "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 47: Leukemia - Hemostasis" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 1 "HPA060788: " "unprognostic (8.85e-2)" "unprognostic (1.69e-1)" "unprognostic (1.96e-3)" "unprognostic (1.41e-1)" "unprognostic (9.94e-2)" "unprognostic (5.71e-2)" "unprognostic (1.48e-1)" "unprognostic (1.91e-1)" "unprognostic (5.20e-2)" "unprognostic (3.29e-1)" "validated prognostic favorable (9.81e-8)" "validated prognostic favorable (1.56e-4)" "unprognostic (3.49e-1)" "unprognostic (3.44e-2)" "unprognostic (2.71e-1)" "unprognostic (1.65e-1)" "unprognostic (6.78e-2)" "unprognostic (2.27e-2)" "unprognostic (3.53e-1)" "unprognostic (4.99e-3)" "unprognostic (2.21e-1)" "unprognostic (2.67e-1)" "unprognostic (3.33e-3)" "unprognostic (6.39e-2)" "unprognostic (1.53e-1)" "unprognostic (3.71e-2)" "unprognostic (1.70e-1)" "potential prognostic unfavorable (2.98e-4)" "unprognostic (1.23e-1)" "unprognostic (1.89e-2)" "unprognostic (6.41e-3)" STARD9 "KIAA1300, KIF16A" ENSG00000159433 "StAR related lipid transfer domain containing 9" Q9P2P6 15 42575606-42720998 "Metabolic proteins, Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 143.2;Fibro-adipogenic progenitors: 305.3;Hematopoietic stem cells: 127.6;Lymphatic endothelial cells: 135.8;Oligodendrocytes: 126.3;Rod photoreceptor cells: 196.8;Sertoli cells: 262.4;Thymocytes: 127.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Spleen - Endothelial cells, Thyroid gland - Fibroblasts" HPA014562 Uncertain NA NA "Cluster 47: Testis - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 3 "HPA014562: " "unprognostic (2.56e-3)" "unprognostic (1.12e-1)" "unprognostic (3.34e-2)" "potential prognostic favorable (4.96e-5)" "unprognostic (9.17e-2)" "unprognostic (5.70e-2)" "unprognostic (2.35e-1)" "unprognostic (8.78e-2)" "unprognostic (2.94e-2)" "unprognostic (1.97e-1)" STAT1 "ISGF-3, STAT91" ENSG00000115415 "Signal transducer and activator of transcription 1" P42224 2 190908460-191020960 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Antiviral defense, Host-virus interaction, Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epicardial cells: 2064.9;Mesothelial cells: 516.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000931, HPA000982, CAB004049" Approved Enhanced Nucleoplasm,Cytosol NA NA 110000 "Cluster 33: Non-specific - ATP binding" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 22: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 93 "Nucleoplasm, Cytosol" "CAB004049: , HPA000931: , HPA000982: " "unprognostic (3.12e-1)" "unprognostic (1.93e-1)" "unprognostic (3.22e-2)" "unprognostic (2.18e-1)" "unprognostic (1.58e-1)" "unprognostic (3.91e-2)" "unprognostic (1.78e-1)" "unprognostic (1.06e-1)" "unprognostic (5.06e-2)" "unprognostic (9.96e-3)" "unprognostic (7.11e-3)" "unprognostic (2.50e-1)" "unprognostic (3.34e-3)" "unprognostic (2.34e-1)" "unprognostic (1.93e-2)" "potential prognostic unfavorable (8.47e-4)" "unprognostic (6.14e-2)" "unprognostic (1.35e-1)" "unprognostic (1.87e-1)" "unprognostic (4.54e-2)" "unprognostic (2.38e-1)" "potential prognostic unfavorable (3.82e-4)" "unprognostic (8.94e-3)" "unprognostic (1.57e-1)" "unprognostic (1.86e-1)" "unprognostic (1.74e-2)" "unprognostic (8.24e-2)" "unprognostic (1.18e-1)" "unprognostic (3.22e-2)" "unprognostic (2.16e-2)" "unprognostic (1.73e-3)" STAT2 STAT113 ENSG00000170581 "Signal transducer and activator of transcription 2" P52630 12 56341597-56360203 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Antiviral defense, Host-virus interaction, Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003858, HPA018888" Approved Supported "Plasma membrane,Cytosol,Mid piece,Principal piece" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 27: Non-specific - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 26 "Cytosol, Mid piece" "Plasma membrane, Principal piece" "CAB003858: , HPA018888: " "unprognostic (8.41e-2)" "unprognostic (4.07e-2)" "unprognostic (2.14e-2)" "unprognostic (1.80e-1)" "unprognostic (1.68e-1)" "unprognostic (1.37e-2)" "unprognostic (3.49e-1)" "unprognostic (1.36e-1)" "unprognostic (1.78e-1)" "unprognostic (3.53e-2)" "potential prognostic favorable (1.60e-6)" "unprognostic (1.40e-1)" "unprognostic (4.09e-2)" "unprognostic (2.22e-1)" "unprognostic (1.64e-3)" "unprognostic (1.82e-1)" "unprognostic (4.18e-2)" "unprognostic (3.43e-2)" "unprognostic (2.00e-1)" "unprognostic (1.06e-1)" "unprognostic (1.53e-1)" "unprognostic (2.52e-2)" "unprognostic (7.20e-2)" "unprognostic (1.78e-1)" "unprognostic (8.91e-2)" "unprognostic (7.05e-2)" "unprognostic (4.74e-2)" "unprognostic (1.81e-1)" "unprognostic (2.72e-1)" "unprognostic (2.74e-2)" "unprognostic (4.26e-2)" STAT3 APRF ENSG00000168610 "Signal transducer and activator of transcription 3" P40763 17 42313324-42388540 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Diabetes mellitus, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 2979.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001671, CAB003859, HPA058603, CAB068241, CAB068242, CAB080518" Supported Enhanced Nucleoplasm,Cytosol NA NA 40000 "Cluster 35: Neutrophils - Protein binding" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 44: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 191 "Nucleoplasm, Cytosol" "CAB003859: , CAB068241: , CAB068242: , CAB080518: , HPA001671: , HPA058603: " "unprognostic (2.20e-2)" "unprognostic (1.39e-1)" "unprognostic (3.00e-1)" "unprognostic (1.50e-1)" "unprognostic (3.62e-2)" "unprognostic (3.87e-3)" "unprognostic (6.03e-2)" "unprognostic (1.08e-2)" "unprognostic (3.90e-2)" "unprognostic (8.99e-3)" "potential prognostic favorable (1.54e-4)" "unprognostic (2.11e-2)" "unprognostic (1.91e-1)" "unprognostic (1.46e-1)" "unprognostic (6.16e-2)" "unprognostic (1.66e-1)" "unprognostic (1.57e-1)" "unprognostic (5.14e-2)" "unprognostic (1.86e-2)" "unprognostic (3.69e-2)" "unprognostic (2.57e-2)" "unprognostic (2.12e-1)" "unprognostic (4.13e-1)" "unprognostic (2.25e-1)" "unprognostic (1.36e-1)" "unprognostic (1.44e-1)" "unprognostic (1.73e-1)" "unprognostic (9.39e-3)" "unprognostic (4.97e-2)" "unprognostic (1.13e-1)" "unprognostic (1.03e-1)" STAT4 ENSG00000138378 "Signal transducer and activator of transcription 4" Q14765 2 191029576-191151596 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 24.1;testis: 27.2" "Cell type enhanced" "Detected in many" "Early spermatids: 353.2;Innate lymphoid cells: 843.2;Late primary spermatocytes: 245.7;monocytes: 333.8;Neutrophils: 265.8;NK-cells: 1245.0;Plasma cells: 260.3;Somatotrophs: 354.6;T-cells: 1066.4;Thymocytes: 493.8" "Cell type enriched" "Detected in many" 5 "leukocyte: 922.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "NK-cells: 76.7;T-cells: 121.5" "Cancer enhanced" "Detected in many" "Myeloma: 7.8" "Adipose visceral - T-cells, Breast - T-cells, Minor Salivary Gland - T-cells, Prostate - T-cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - T-cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA001860, CAB013108" Enhanced Supported "Nucleoplasm,Nuclear bodies,Flagellar centriole" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 35: Non-specific - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 8 "Nucleoplasm, Nuclear bodies" "Flagellar centriole" "CAB013108: , HPA001860: " "unprognostic (2.20e-2)" "potential prognostic favorable (3.11e-5)" "unprognostic (9.19e-2)" "unprognostic (1.55e-2)" "unprognostic (2.10e-1)" "unprognostic (1.16e-1)" "unprognostic (1.44e-1)" "unprognostic (2.56e-1)" "unprognostic (5.32e-3)" "unprognostic (1.65e-1)" "unprognostic (4.48e-3)" "unprognostic (2.72e-2)" "unprognostic (1.33e-3)" "unprognostic (1.66e-1)" "unprognostic (1.44e-1)" "unprognostic (4.65e-2)" "unprognostic (5.71e-2)" "unprognostic (1.01e-3)" "potential prognostic unfavorable (8.36e-4)" "unprognostic (2.54e-1)" "unprognostic (7.93e-2)" "unprognostic (1.97e-2)" "unprognostic (3.59e-2)" "unprognostic (2.32e-1)" "unprognostic (1.89e-1)" "unprognostic (1.99e-1)" "unprognostic (7.90e-2)" STAT5A "MGF, STAT5" ENSG00000126561 "Signal transducer and activator of transcription 5A" P42229 17 42287547-42311943 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Lactation, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 74.1" "Cell type enhanced" "Detected in many" "Adipocytes: 93.0;Breast lactating cells: 212.5;Epicardial cells: 125.1;Megakaryocyte progenitors: 102.1;Megakaryocyte-Erythroid progenitors: 121.7;monocytes: 80.1;Neutrophils: 145.3" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 35.7;leukocyte: 37.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 91.6" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB003860, HPA027873, HPA042128, HPA049883, HPA051156" Enhanced Enhanced Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 47: Leukemia - Hemostasis" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 48 Cytosol Nucleoplasm "CAB003860: , HPA027873: , HPA042128: , HPA049883: , HPA051156: " "unprognostic (3.35e-2)" "unprognostic (5.67e-3)" "unprognostic (1.08e-2)" "unprognostic (5.84e-2)" "unprognostic (1.88e-1)" "unprognostic (1.73e-1)" "unprognostic (1.09e-1)" "unprognostic (3.08e-2)" "unprognostic (5.24e-3)" "unprognostic (2.14e-2)" "unprognostic (5.86e-2)" "unprognostic (1.46e-1)" "unprognostic (2.54e-3)" "unprognostic (3.72e-1)" "unprognostic (1.58e-1)" "unprognostic (4.80e-2)" "unprognostic (1.09e-1)" "unprognostic (1.03e-1)" "unprognostic (2.00e-1)" "potential prognostic unfavorable (1.69e-4)" "unprognostic (2.08e-1)" "unprognostic (2.90e-1)" "unprognostic (5.90e-2)" "unprognostic (5.15e-1)" "unprognostic (1.19e-1)" "unprognostic (4.58e-3)" "unprognostic (2.70e-1)" "unprognostic (2.93e-2)" "unprognostic (3.25e-2)" "unprognostic (1.50e-1)" "unprognostic (7.41e-2)" STAT5B ENSG00000173757 "Signal transducer and activator of transcription 5B" P51692 17 42199176-42288633 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Neutrophils: 1497.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Pancreas - Endothelial cells, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004298, CAB005418, HPA042128, HPA049883, HPA051156" Approved Supported Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 24: Non-specific - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 59: Leukemia - T-cell receptor" "Cluster 24: Neutrophils - Innate immunity signal integration" 28 Cytosol "CAB004298: , CAB005418: , HPA042128: , HPA049883: , HPA051156: " "unprognostic (3.74e-3)" "unprognostic (1.93e-1)" "unprognostic (6.36e-2)" "unprognostic (5.10e-2)" "unprognostic (1.18e-1)" "unprognostic (6.45e-2)" "unprognostic (3.43e-1)" "unprognostic (2.49e-3)" "unprognostic (3.01e-1)" "unprognostic (5.33e-2)" "validated prognostic favorable (1.27e-8)" "validated prognostic favorable (1.44e-5)" "unprognostic (1.25e-2)" "unprognostic (2.04e-1)" "unprognostic (1.11e-1)" "unprognostic (1.22e-1)" "unprognostic (1.25e-1)" "unprognostic (9.15e-2)" "unprognostic (1.67e-1)" "unprognostic (1.11e-2)" "unprognostic (2.10e-1)" "potential prognostic favorable (8.97e-4)" "unprognostic (8.23e-2)" "unprognostic (2.63e-1)" "unprognostic (4.71e-3)" "unprognostic (1.43e-3)" "unprognostic (2.06e-1)" "unprognostic (1.97e-1)" "unprognostic (4.20e-1)" "unprognostic (2.90e-1)" "unprognostic (1.68e-1)" STAT6 "D12S1644, IL-4-STAT" ENSG00000166888 "Signal transducer and activator of transcription 6" P42226 12 57095408-57132139 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 238.9;Neutrophils: 342.6" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 85.5;leukocyte: 85.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001861 Approved Supported "Nucleoplasm,Cytosol,Connecting piece" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 61: Non-specific - Transcription" "Cluster 23: Choroid plexus - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 17 "Nucleoplasm, Cytosol" "Connecting piece" "HPA001861: " "unprognostic (1.18e-1)" "unprognostic (2.30e-1)" "unprognostic (9.87e-2)" "unprognostic (3.09e-2)" "unprognostic (8.04e-2)" "unprognostic (1.04e-1)" "unprognostic (1.86e-2)" "unprognostic (1.11e-1)" "unprognostic (1.75e-1)" "unprognostic (9.89e-2)" "potential prognostic favorable (1.15e-4)" "unprognostic (5.32e-2)" "unprognostic (1.14e-3)" "unprognostic (2.94e-1)" "unprognostic (2.01e-3)" "unprognostic (2.12e-1)" "unprognostic (1.61e-1)" "unprognostic (8.76e-2)" "unprognostic (5.25e-2)" "unprognostic (6.34e-2)" "unprognostic (7.54e-2)" "unprognostic (1.99e-2)" "unprognostic (1.53e-1)" "unprognostic (1.35e-1)" "unprognostic (4.61e-2)" "unprognostic (1.34e-1)" "unprognostic (6.18e-2)" "unprognostic (1.77e-1)" "unprognostic (7.43e-2)" "unprognostic (7.96e-3)" "unprognostic (8.74e-2)" STATH STR ENSG00000126549 Statherin P02808 4 69995966-70002570 "Plasma proteins, Predicted secreted proteins, Transporters" Biomineralization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 921 "salivary gland: 8578.0" "Group enriched" "Detected in some" 18 "Salivary acinar cells: 59339.7;Salivary myoepithelial cells: 15709.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Lung Squamous Cell Carcinoma (TCGA): 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "Sarcoma: 2.3" "Minor Salivary Gland - Minor salivary glandular cells" HPA044569 Enhanced "Secreted to digestive system" Other NA NA 8600000 "Cluster 82: Salivary gland - Secretion" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 21 "HPA044569: " "unprognostic (5.95e-2)" "unprognostic (3.93e-1)" STAU1 "PPP1R150, STAU" ENSG00000124214 "Staufen double-stranded RNA binding protein 1" O95793 20 49113339-49188367 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020839, HPA049892, HPA072004" Approved Enhanced Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 455 Cytosol "CAB020839: , HPA049892: , HPA072004: " "unprognostic (1.84e-1)" "unprognostic (1.52e-1)" "unprognostic (2.42e-1)" "unprognostic (5.49e-2)" "unprognostic (1.11e-1)" "unprognostic (6.24e-2)" "unprognostic (2.33e-1)" "unprognostic (7.59e-3)" "unprognostic (1.31e-1)" "potential prognostic unfavorable (1.16e-4)" "potential prognostic favorable (1.27e-7)" "unprognostic (1.27e-1)" "unprognostic (2.67e-1)" "potential prognostic unfavorable (9.36e-4)" "unprognostic (8.08e-2)" "unprognostic (5.69e-2)" "potential prognostic unfavorable (2.15e-5)" "unprognostic (5.86e-3)" "unprognostic (9.62e-2)" "unprognostic (1.25e-2)" "unprognostic (4.12e-2)" "unprognostic (7.42e-3)" "unprognostic (1.11e-1)" "unprognostic (9.76e-3)" "unprognostic (1.73e-2)" "unprognostic (3.81e-2)" "unprognostic (3.54e-1)" "unprognostic (2.55e-1)" "unprognostic (1.03e-1)" "unprognostic (5.19e-2)" "unprognostic (1.53e-1)" STAU2 39K2 ENSG00000040341 "Staufen double-stranded RNA binding protein 2" Q9NUL3 8 73420369-73747708 "Predicted intracellular proteins" Transport RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Choroid plexus epithelial cells: 373.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019155, CAB020836, HPA075293" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 40: Non-specific - Unknown function" "Cluster 109: Neurons - Neuronal signaling" 41 Nucleoplasm Cytosol "CAB020836: , HPA019155: , HPA075293: " "unprognostic (3.25e-2)" "unprognostic (1.89e-2)" "unprognostic (1.84e-1)" "unprognostic (3.73e-3)" "unprognostic (1.86e-2)" "unprognostic (1.99e-1)" "unprognostic (3.30e-1)" "unprognostic (2.77e-3)" "unprognostic (3.70e-2)" "potential prognostic unfavorable (5.50e-6)" "potential prognostic favorable (8.62e-4)" "unprognostic (4.21e-2)" "unprognostic (2.58e-1)" "unprognostic (9.55e-3)" "unprognostic (2.65e-1)" "unprognostic (3.22e-1)" "unprognostic (9.86e-2)" "unprognostic (1.56e-1)" "unprognostic (2.72e-1)" "unprognostic (3.89e-3)" "unprognostic (1.55e-3)" "unprognostic (2.92e-2)" "unprognostic (1.45e-2)" "unprognostic (1.04e-1)" "unprognostic (4.25e-2)" "unprognostic (1.07e-1)" "unprognostic (6.98e-2)" "unprognostic (2.56e-2)" "unprognostic (2.47e-1)" "unprognostic (9.20e-3)" "unprognostic (1.13e-1)" STBD1 "FLJ41801, GENX-3414" ENSG00000118804 "Starch binding domain 1" O95210 4 76306733-76311130 "Plasma proteins, Predicted intracellular proteins, Transporters" "Autophagy, Carbohydrate metabolism, Glycogen metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 121.8;skeletal muscle: 232.9;tongue: 144.4" "Cell type enhanced" "Detected in some" "Colonocytes: 7.1;Endometrial luminal cells: 3.4;Enterocytes: 15.0;Fallopian tube ciliated cells: 4.5;Goblet cells: 3.5;Myonuclei: 3.5;Other brain neurons: 3.8;Urothelial cells: 5.0" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 61.9" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Macrophages, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA011952, HPA012849" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 26 "Endoplasmic reticulum" "HPA011952: , HPA012849: " "unprognostic (3.78e-2)" "unprognostic (1.17e-2)" "unprognostic (9.74e-3)" "unprognostic (1.21e-3)" "unprognostic (3.20e-1)" "unprognostic (1.06e-1)" "unprognostic (1.02e-2)" "potential prognostic unfavorable (9.91e-5)" "unprognostic (6.22e-3)" "unprognostic (7.36e-2)" "potential prognostic favorable (9.72e-5)" "unprognostic (6.42e-3)" "unprognostic (4.67e-1)" "unprognostic (1.58e-1)" "unprognostic (8.68e-3)" "unprognostic (1.41e-2)" "potential prognostic unfavorable (1.62e-4)" "unprognostic (7.09e-3)" "unprognostic (5.66e-3)" "unprognostic (2.11e-2)" "unprognostic (5.51e-2)" "unprognostic (1.83e-1)" "unprognostic (3.49e-1)" "unprognostic (1.27e-1)" "unprognostic (3.58e-2)" "unprognostic (1.11e-1)" "unprognostic (2.80e-1)" "unprognostic (7.31e-2)" "unprognostic (5.86e-2)" "unprognostic (1.72e-1)" "unprognostic (1.26e-1)" STC1 STC ENSG00000159167 "Stanniocalcin 1" P52823 8 23841929-23854806 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 159.0;Endometrial glandular cells: 447.1;Endometrial luminal cells: 286.1;Endometrial secretory cells: 166.9;Gastric chief cells: 80.8;Lymphatic endothelial cells: 103.0;Renal connecting tubule cells: 107.0;Vascular endothelial cells: 264.7" "Group enriched" "Detected in many" 5 "eccentric medium spiny neuron: 14.1;endothelial cell: 28.4;mammillary body: 30.9;midbrain-derived inhibitory: 28.2;splatter: 11.5;thalamic excitatory: 9.1" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 78.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB018625, HPA023918" Approved "Secreted in other tissues" Hormone NA NA 410000 "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 44: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 1 "CAB018625: , HPA023918: " "unprognostic (2.94e-2)" "unprognostic (1.45e-1)" "unprognostic (3.97e-1)" "unprognostic (1.55e-3)" "unprognostic (1.11e-1)" "unprognostic (7.13e-2)" "potential prognostic unfavorable (6.72e-6)" "unprognostic (4.20e-3)" "unprognostic (4.64e-3)" "unprognostic (9.20e-2)" "unprognostic (3.66e-2)" "unprognostic (8.31e-3)" "potential prognostic unfavorable (2.28e-5)" "unprognostic (1.87e-3)" "unprognostic (7.04e-2)" "unprognostic (1.03e-3)" "unprognostic (1.97e-2)" "unprognostic (1.83e-2)" "unprognostic (1.83e-1)" "unprognostic (1.26e-1)" "unprognostic (2.49e-2)" "unprognostic (7.35e-2)" "potential prognostic unfavorable (8.05e-4)" "unprognostic (1.89e-1)" "unprognostic (3.15e-1)" "unprognostic (6.66e-2)" "unprognostic (2.80e-1)" "unprognostic (1.12e-3)" "unprognostic (1.59e-1)" "potential prognostic unfavorable (1.28e-4)" "unprognostic (9.48e-2)" STC2 STC-2 ENSG00000113739 "Stanniocalcin 2" O76061 5 173314723-173328447 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "breast: 135.0" "Cell type enriched" "Detected in some" 4 "Breast hormone-responsive cells: 628.9" "Cell type enhanced" "Detected in some" "hippocampal CA1-3: 2.3;hippocampal CA4: 2.6" "Cancer enriched" "Detected in all" 4 "Breast Invasive Carcinoma (TCGA): 215.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Breast - Breast glandular cells, Skin - Macrophages" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" HPA045372 Approved Approved "Endoplasmic reticulum" "Secreted in other tissues" Hormone NA NA 3000000 "Cluster 55: Breast - Lactation" "Cluster 27: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 2 "Endoplasmic reticulum" "HPA045372: " "unprognostic (2.83e-1)" "potential prognostic favorable (5.97e-4)" "unprognostic (2.96e-2)" "unprognostic (5.02e-2)" "unprognostic (5.80e-2)" "unprognostic (9.38e-2)" "unprognostic (4.01e-3)" "unprognostic (1.94e-1)" "potential prognostic unfavorable (7.11e-5)" "unprognostic (8.55e-2)" "unprognostic (1.78e-2)" "unprognostic (4.75e-2)" "potential prognostic unfavorable (1.21e-6)" "potential prognostic unfavorable (1.26e-5)" "unprognostic (6.22e-2)" "unprognostic (1.70e-3)" "unprognostic (3.15e-3)" "unprognostic (5.14e-2)" "unprognostic (2.50e-1)" "unprognostic (1.72e-1)" "unprognostic (8.71e-2)" "unprognostic (2.77e-1)" "unprognostic (4.82e-2)" "unprognostic (1.96e-1)" "unprognostic (7.68e-3)" "unprognostic (6.92e-2)" "unprognostic (6.11e-2)" "unprognostic (1.91e-3)" "unprognostic (1.92e-1)" "unprognostic (1.04e-2)" "unprognostic (7.17e-2)" STEAP1 "PRSS24, STEAP" ENSG00000164647 "STEAP family member 1" Q9UHE8 7 90154456-90164829 "Cancer-related genes, Predicted membrane proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 78.6" "Cell type enhanced" "Detected in many" "Epicardial cells: 54.6;Gastric progenitor cells: 98.7;Mesothelial cells: 50.8;Prostatic club cells: 78.8;Prostatic glandular cells: 234.6;Prostatic hillock cells: 43.3;Respiratory basal cells: 44.2;Respiratory secretory cells: 87.9" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in all" 5 "Prostate Adenocarcinoma (TCGA): 188.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "prostate cancer: 177.2" "Kidney - Proximal tubular cells, Prostate - Prostate glandular cells, Testis - Spermatocytes, Testis - Spermatogonia" HPA030985 Uncertain NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 14: Neurons - Synaptic function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 2 "HPA030985: " "unprognostic (3.58e-1)" "unprognostic (9.19e-3)" "unprognostic (1.25e-1)" "unprognostic (1.65e-1)" "unprognostic (2.20e-1)" "unprognostic (2.09e-1)" "unprognostic (3.47e-3)" "unprognostic (4.58e-3)" "unprognostic (1.07e-1)" "unprognostic (5.41e-2)" "potential prognostic favorable (3.62e-5)" "unprognostic (2.00e-2)" "unprognostic (7.64e-3)" "unprognostic (5.48e-3)" "potential prognostic unfavorable (9.87e-4)" "validated prognostic unfavorable (7.80e-7)" "validated prognostic unfavorable (2.89e-5)" "unprognostic (9.96e-3)" "unprognostic (9.62e-2)" "unprognostic (2.64e-2)" "unprognostic (2.98e-1)" "unprognostic (6.08e-3)" "unprognostic (2.03e-1)" "unprognostic (1.55e-1)" "unprognostic (9.87e-2)" "unprognostic (3.82e-1)" "unprognostic (3.44e-1)" "unprognostic (1.42e-1)" "unprognostic (4.27e-1)" "unprognostic (9.56e-2)" "unprognostic (1.44e-1)" STEAP1B ENSG00000105889 "STEAP family member 1B" Q6NZ63 7 22419444-22727613 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 5.4" "Cell type enhanced" "Detected in many" "Enteric stem cells: 775.6;Enteric transient amplifying cells: 591.7;Enterocytes: 370.3;Epididymal basal cells: 517.5;Epididymal clear cells: 504.2;Epididymal efferent duct absorptive cells: 545.7;Epididymal principal cells: 475.1;Goblet cells: 423.4;Paneth cells: 626.5" "Group enriched" "Detected in all" 5 "central nervous system macrophage: 169.6;choroid plexus epithelial cell: 285.6;oligodendrocyte: 84.4" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 17.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 67 "memory B-cell: 8.4;naive B-cell: 4.9" "Lineage enriched" "Detected in single" 85 "B-cells: 8.4" "Cancer enhanced" "Detected in many" "skin cancer: 30.8" "Breast - Endothelial cells" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 15: Non-specific - Protein processing" 3 "potential prognostic unfavorable (5.39e-4)" "unprognostic (1.07e-2)" "unprognostic (2.58e-2)" "unprognostic (4.56e-2)" "unprognostic (1.25e-1)" "unprognostic (1.09e-1)" "unprognostic (4.68e-3)" "unprognostic (6.36e-3)" "unprognostic (2.99e-1)" "unprognostic (7.53e-2)" "unprognostic (6.61e-3)" "unprognostic (5.44e-2)" "unprognostic (8.62e-2)" "unprognostic (4.37e-2)" "unprognostic (1.68e-2)" "potential prognostic unfavorable (3.55e-6)" STEAP2 "IPCA-1, PCANAP1, STAMP1, STMP" ENSG00000157214 "STEAP2 metalloreductase" Q8NFT2 7 90167590-90238137 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Electron transport, Ion transport, Iron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "prostate: 119.9" "Group enriched" "Detected in many" 5 "Epicardial cells: 307.0;Prostatic glandular cells: 1089.6" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 13 "Prostate Adenocarcinoma (TCGA): 195.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 90.6" "Prostate - Prostate glandular cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029115, HPA055603" Uncertain Supported Vesicles NA NA "Cluster 38: Non-specific - Basic cellular processes" "Cluster 53: Neurons - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" Vesicles "HPA029115: , HPA055603: " "unprognostic (6.85e-3)" "unprognostic (1.59e-2)" "unprognostic (2.53e-2)" "unprognostic (6.31e-2)" "unprognostic (5.37e-2)" "unprognostic (1.71e-2)" "potential prognostic unfavorable (5.07e-4)" "unprognostic (2.30e-3)" "unprognostic (1.89e-1)" "unprognostic (3.54e-2)" "validated prognostic favorable (1.81e-5)" "validated prognostic favorable (1.89e-4)" "unprognostic (2.87e-1)" "unprognostic (1.06e-1)" "potential prognostic unfavorable (2.20e-5)" "potential prognostic unfavorable (1.34e-5)" "unprognostic (5.40e-3)" "unprognostic (4.69e-2)" "unprognostic (1.92e-1)" "unprognostic (4.01e-1)" "unprognostic (1.06e-1)" "unprognostic (1.45e-1)" "unprognostic (2.76e-1)" "unprognostic (8.56e-2)" "unprognostic (2.73e-1)" "unprognostic (3.33e-1)" "unprognostic (2.19e-2)" "unprognostic (8.12e-2)" "potential prognostic unfavorable (4.22e-5)" "unprognostic (1.73e-1)" STEAP3 "dudlin-2, STMP3, TSAP6" ENSG00000115107 "STEAP3 metalloreductase" Q658P3 2 119223831-119265652 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Apoptosis, Cell cycle, Ion transport, Iron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 180.3;parathyroid gland: 74.2" "Cell type enhanced" "Detected in many" "Breast lactating cells: 48.0;Conjunctival goblet cells: 61.2;Cytotrophoblasts: 46.4;Hepatocytes: 100.5;Respiratory ciliated cells: 69.5;Thymic myoid cells: 44.9" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 30.6;choroid plexus epithelial cell: 22.2;lower rhombic lip: 26.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.4;intermediate monocyte: 2.7;myeloid DC: 4.1;NK-cell: 1.3" "Group enriched" "Detected in many" 6 "dendritic cells: 4.1;monocytes: 2.7;NK-cells: 1.3" "Low cancer specificity" "Detected in all" "Colon - Macrophages, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA050510 Approved Approved Nucleoli,Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 53: Liver - Plasma proteins" "Cluster 49: Hindbrain - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 16 Cytosol Nucleoli "HPA050510: " "unprognostic (1.04e-1)" "unprognostic (8.64e-2)" "unprognostic (1.55e-1)" "unprognostic (1.01e-1)" "unprognostic (4.12e-2)" "unprognostic (1.09e-1)" "validated prognostic unfavorable (1.87e-4)" "validated prognostic unfavorable (5.14e-4)" "unprognostic (9.79e-2)" "unprognostic (8.98e-2)" "validated prognostic unfavorable (4.71e-10)" "validated prognostic unfavorable (3.10e-4)" "unprognostic (1.30e-2)" "unprognostic (2.06e-2)" "unprognostic (1.73e-2)" "unprognostic (5.48e-2)" "unprognostic (1.44e-1)" "unprognostic (6.82e-3)" "unprognostic (3.59e-3)" "potential prognostic unfavorable (5.51e-4)" "unprognostic (2.39e-1)" "potential prognostic unfavorable (4.59e-4)" "unprognostic (1.58e-1)" "unprognostic (1.63e-1)" "unprognostic (1.42e-1)" "unprognostic (4.38e-3)" "unprognostic (1.91e-1)" "unprognostic (2.74e-1)" "unprognostic (2.68e-1)" "unprognostic (1.14e-1)" "unprognostic (2.08e-2)" STEAP4 "FLJ23153, SchLAH, STAMP2, TIARP, TNFAIP9" ENSG00000127954 "STEAP4 metalloreductase" Q687X5 7 88270892-88306894 "Enzymes, Predicted membrane proteins, Transporters" "Electron transport, Ion transport, Iron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 106.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 288.2;Conjunctival goblet cells: 310.7;Neutrophils: 826.0;Pancreatic acinar cells: 270.3;Pericytes: 1115.7;Respiratory secretory cells: 272.4;Transitional alveolar cells: 282.5" "Cell type enriched" "Detected in many" 4 "fibroblast: 39.7" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 109.9" "Region enriched" "Detected in all" 4 "choroid plexus: 39.4" "Immune cell enriched" "Detected in some" 12 "neutrophil: 161.9" "Lineage enriched" "Detected in many" 12 "granulocytes: 161.9" "Cancer enriched" "Detected in many" 6 "cervical cancer: 90.3" "Breast - Endothelial cells, Colon - Endothelial cells, Skeletal muscle - Endothelial cells, Spleen - Neutrophils_2, Stomach - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA065201 Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 23: Choroid plexus - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 110: Mural cells - ECM organization" "Nucleoplasm, Plasma membrane" "HPA065201: " "unprognostic (1.02e-1)" "unprognostic (9.18e-2)" "unprognostic (1.94e-1)" "unprognostic (2.28e-3)" "unprognostic (2.70e-1)" "unprognostic (1.75e-1)" "unprognostic (5.61e-2)" "unprognostic (1.79e-1)" "unprognostic (6.02e-2)" "unprognostic (2.42e-3)" "unprognostic (9.47e-3)" "unprognostic (1.48e-2)" "unprognostic (1.24e-3)" "potential prognostic favorable (1.91e-4)" "unprognostic (4.99e-2)" "unprognostic (2.75e-1)" "unprognostic (1.86e-1)" "unprognostic (1.75e-1)" "unprognostic (1.00e-2)" "unprognostic (2.28e-1)" "unprognostic (2.60e-1)" "unprognostic (3.98e-2)" "unprognostic (1.73e-1)" "potential prognostic unfavorable (1.51e-4)" "unprognostic (1.84e-1)" "unprognostic (4.28e-2)" "unprognostic (1.04e-3)" "unprognostic (4.22e-2)" "unprognostic (2.85e-1)" "unprognostic (1.17e-1)" STEEP1 "CXorf56, FLJ22965" ENSG00000018610 "STING1 ER exit protein 1" Q9H5V9 X 119538149-119565409 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 55.3;Syncytiotrophoblasts: 56.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038245, HPA038617, HPA064831" Uncertain Supported Nucleoplasm,Centrosome NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 36: Non-specific - mRNA processing" "Cluster 7: Non-specific - Transcription" 7 Nucleoplasm Centrosome "HPA038245: , HPA038617: , HPA064831: " "unprognostic (1.73e-1)" "potential prognostic unfavorable (3.67e-4)" "unprognostic (2.57e-1)" "unprognostic (3.89e-1)" "unprognostic (2.38e-2)" "unprognostic (2.23e-1)" "unprognostic (3.03e-1)" "unprognostic (1.67e-2)" "unprognostic (3.72e-2)" "unprognostic (2.64e-2)" "potential prognostic favorable (4.27e-5)" "unprognostic (1.86e-3)" "unprognostic (9.10e-2)" "unprognostic (1.73e-3)" "unprognostic (1.30e-2)" "unprognostic (1.70e-1)" "unprognostic (3.98e-3)" "unprognostic (2.58e-1)" "unprognostic (1.95e-1)" "unprognostic (1.38e-1)" "unprognostic (2.76e-1)" "unprognostic (5.73e-2)" "unprognostic (5.54e-2)" "unprognostic (3.18e-3)" "unprognostic (6.31e-3)" "unprognostic (2.93e-1)" "unprognostic (4.17e-2)" "unprognostic (9.90e-3)" "unprognostic (2.54e-2)" "unprognostic (3.42e-1)" "unprognostic (2.77e-1)" STH MAPTIT ENSG00000256762 Saitohin Q8IWL8 17 45999250-45999694 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA069024 Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 12: Bone cancer - Neuronal signaling" 17 "Nucleoplasm, Golgi apparatus" Cytosol "HPA069024: " "unprognostic (2.13e-1)" "potential prognostic favorable (2.51e-4)" STIL "MCPH7, SIL" ENSG00000123473 "STIL centriolar assembly protein" Q15468 1 47250139-47314892 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Cancer-related genes, Disease variant, Intellectual disability, Primary microcephaly, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 8.4;lymphoid tissue: 8.2" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 43.8;Endometrial glandular cells: 55.3;Erythrocyte progenitors: 87.9;Megakaryocyte progenitors: 62.9;Monocyte progenitors: 96.9;Neutrophil progenitors: 59.9;Respiratory deuterosomal cells: 91.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA028388 Supported "Nucleoplasm,Centrosome,Basal body,Cytosol" NA Yes "Cluster 13: Non-specific - Mitochondria" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 34: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 27: Non-specific - Cell proliferation" 30 "Nucleoplasm, Centrosome, Basal body" Cytosol "HPA028388: " "unprognostic (1.90e-1)" "unprognostic (5.59e-2)" "unprognostic (2.82e-1)" "unprognostic (2.03e-1)" "unprognostic (1.18e-1)" "unprognostic (2.56e-2)" "unprognostic (3.35e-1)" "unprognostic (3.26e-2)" "unprognostic (3.94e-2)" "unprognostic (6.31e-3)" "potential prognostic unfavorable (5.05e-4)" "potential prognostic unfavorable (9.24e-4)" "potential prognostic unfavorable (1.04e-5)" "unprognostic (1.85e-3)" "unprognostic (1.39e-3)" "potential prognostic unfavorable (4.05e-4)" "unprognostic (6.53e-2)" "unprognostic (1.59e-2)" "unprognostic (1.41e-1)" "unprognostic (2.23e-1)" "unprognostic (1.15e-3)" "unprognostic (1.20e-1)" "unprognostic (3.86e-2)" "unprognostic (1.86e-3)" "unprognostic (3.03e-1)" "unprognostic (8.01e-3)" "unprognostic (1.19e-2)" "unprognostic (1.43e-1)" "unprognostic (2.89e-2)" STIM1 "D11S4896E, GOK" ENSG00000167323 "Stromal interaction molecule 1" Q13586 11 3854527-4093210 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Myonuclei: 525.6;Neutrophil progenitors: 769.5;Neutrophils: 723.8;Thymic myoid cells: 621.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011088, HPA012123, CAB037128, CAB037288" Enhanced Enhanced "Endoplasmic reticulum" NA NA 1100000 "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 59: Leukemia - T-cell receptor" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 73 "Endoplasmic reticulum" "CAB037128: , CAB037288: , HPA011088: , HPA012123: " "unprognostic (9.49e-2)" "unprognostic (3.30e-2)" "unprognostic (3.62e-1)" "unprognostic (1.61e-1)" "unprognostic (1.69e-1)" "unprognostic (1.44e-1)" "unprognostic (1.47e-1)" "unprognostic (2.98e-3)" "unprognostic (3.79e-1)" "unprognostic (7.31e-2)" "potential prognostic favorable (7.17e-4)" "unprognostic (1.91e-1)" "unprognostic (6.52e-2)" "unprognostic (1.07e-1)" "unprognostic (7.34e-2)" "unprognostic (1.60e-1)" "unprognostic (7.37e-2)" "unprognostic (4.00e-2)" "unprognostic (2.87e-1)" "unprognostic (3.68e-2)" "unprognostic (7.55e-2)" "unprognostic (6.98e-2)" "unprognostic (4.75e-1)" "unprognostic (1.28e-1)" "unprognostic (7.54e-2)" "unprognostic (7.64e-2)" "unprognostic (3.82e-1)" "unprognostic (3.35e-1)" "unprognostic (2.01e-1)" "unprognostic (1.09e-1)" "unprognostic (1.24e-1)" STIM2 ENSG00000109689 "Stromal interaction molecule 2" Q9P246 4 26857601-27025381 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 59.3" "Cell type enhanced" "Detected in all" "Choroid plexus epithelial cells: 853.4;Conjunctival goblet cells: 355.3;Renal connecting tubule cells: 361.7" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 1010.9" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "choroid plexus: 181.3" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036933, CAB037196, HPA057511" Supported NA NA "Cluster 24: Non-specific - Transcription" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 16 "CAB037196: , HPA036933: , HPA057511: " "unprognostic (3.72e-2)" "unprognostic (2.82e-1)" "unprognostic (1.00e-1)" "unprognostic (1.78e-1)" "unprognostic (3.55e-2)" "unprognostic (3.39e-2)" "unprognostic (1.23e-1)" "unprognostic (4.03e-1)" "unprognostic (1.81e-2)" "unprognostic (9.07e-3)" "unprognostic (5.10e-3)" "potential prognostic favorable (7.25e-5)" "unprognostic (3.17e-1)" "potential prognostic unfavorable (5.93e-7)" "unprognostic (9.15e-3)" "unprognostic (1.20e-1)" "unprognostic (1.96e-2)" "unprognostic (1.27e-2)" "unprognostic (6.94e-2)" "unprognostic (1.21e-1)" "unprognostic (8.56e-2)" "unprognostic (7.46e-3)" "unprognostic (2.38e-1)" "unprognostic (7.16e-2)" "unprognostic (7.37e-3)" "unprognostic (8.68e-2)" "unprognostic (1.06e-1)" "unprognostic (7.25e-2)" "unprognostic (6.63e-2)" "unprognostic (4.37e-2)" "unprognostic (2.12e-1)" STIMATE "MGC52022, TMEM110" ENSG00000213533 "STIM activating enhancer" Q86TL2 3 52836219-52897548 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 27.3;Bergmann glia: 30.4;Brain excitatory neurons: 23.3;Brain inhibitory neurons: 21.9;Choroid plexus epithelial cells: 19.9;Ependymal cells: 19.9;Late spermatids: 11.6;Microglia: 38.1;Oligodendrocyte progenitor cells: 25.0;Oligodendrocytes: 28.4;Oocytes: 9.2;Other brain neurons: 20.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051855 Uncertain Approved Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 22: Non-specific - Basic cellular functions" Cytosol "HPA051855: " "unprognostic (3.60e-1)" "unprognostic (7.51e-2)" "unprognostic (1.22e-1)" "unprognostic (3.56e-1)" "unprognostic (9.02e-2)" "unprognostic (7.99e-2)" "unprognostic (1.07e-1)" "unprognostic (9.70e-2)" "unprognostic (1.37e-3)" "potential prognostic favorable (1.32e-4)" "unprognostic (2.83e-2)" "unprognostic (5.10e-2)" "unprognostic (1.31e-1)" "unprognostic (1.09e-2)" "unprognostic (1.90e-1)" "unprognostic (1.88e-2)" "unprognostic (3.19e-1)" "unprognostic (1.54e-1)" "unprognostic (4.47e-2)" "unprognostic (2.44e-1)" "unprognostic (8.73e-2)" "unprognostic (2.06e-2)" "unprognostic (1.70e-2)" "unprognostic (7.89e-2)" "unprognostic (2.28e-2)" "unprognostic (1.54e-1)" "unprognostic (1.57e-1)" "unprognostic (4.43e-1)" "unprognostic (4.20e-1)" STIMATE-MUSTN1 TMEM110-MUSTN1 ENSG00000248592 "STIMATE-MUSTN1 readthrough" 3 52833121-52897562 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "liver: 11.4" "Cell type enhanced" "Detected in some" "Neutrophil progenitors: 1.0;Vascular smooth muscle cells: 2.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" HPA051855 Uncertain Approved Cytosol NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 30: White matter - Myelination" "Cluster 40: Non-specific - Unknown function" "Cluster 62: Smooth muscle cells - Muscle contraction" Cytosol "HPA051855: " "unprognostic (1.59e-1)" "unprognostic (6.81e-2)" "unprognostic (3.88e-2)" "unprognostic (1.30e-1)" "unprognostic (4.96e-2)" "unprognostic (4.99e-2)" "unprognostic (2.72e-1)" "unprognostic (1.12e-1)" "unprognostic (1.27e-1)" "unprognostic (2.68e-1)" "unprognostic (1.13e-1)" "unprognostic (4.21e-1)" STING1 "ERIS, FLJ38577, MITA, MPYS, NET23, STING, TMEM173" ENSG00000184584 "Stimulator of interferon response cGAMP interactor 1" Q86WV6 5 139475533-139482935 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Autophagy, Host-virus interaction, Immunity, Innate immunity, Ion transport, Transport" "Ion channel" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 26.2;Endometrial secretory cells: 9.1;Hepatic stellate cells: 6.5;Medullary thymic epithelial cells: 7.2;Microglia: 30.7;Papillary tip epithelial cells: 10.6;Renal collecting duct principal cells: 6.2" "Group enriched" "Detected in many" 5 "central nervous system macrophage: 37.4;choroid plexus epithelial cell: 39.6;endothelial cell: 31.2;fibroblast: 31.5;leukocyte: 32.0;pericyte: 60.4;vascular associated smooth muscle cell: 31.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "choroid plexus: 21.0" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Colon - Endothelial cells, Liver - Vascular endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA038116, HPA038534, CAB080401" Enhanced Supported "Nucleoplasm,Vesicles,Primary cilium,Basal body,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 102: Non-specific - Mixed function" 67 Cytosol "Nucleoplasm, Vesicles, Primary cilium, Basal body" "CAB080401: , HPA038116: , HPA038534: " "unprognostic (1.07e-1)" "unprognostic (1.61e-1)" "unprognostic (3.24e-1)" "unprognostic (9.74e-2)" "unprognostic (2.37e-1)" "unprognostic (1.56e-1)" "unprognostic (2.86e-1)" "unprognostic (2.70e-2)" "unprognostic (2.30e-3)" "unprognostic (5.87e-2)" "unprognostic (7.03e-2)" "potential prognostic unfavorable (6.29e-4)" "unprognostic (1.70e-2)" "unprognostic (8.72e-2)" "unprognostic (2.23e-2)" "unprognostic (3.05e-1)" "unprognostic (2.33e-1)" "unprognostic (1.13e-1)" "unprognostic (2.95e-1)" "unprognostic (6.56e-2)" "unprognostic (3.62e-2)" "unprognostic (6.90e-2)" "unprognostic (2.05e-3)" "unprognostic (6.03e-2)" "unprognostic (1.58e-1)" "unprognostic (4.73e-2)" "unprognostic (4.48e-2)" "unprognostic (8.63e-2)" "unprognostic (3.91e-2)" STIP1 "HOP, STI1" ENSG00000168439 "Stress induced phosphoprotein 1" P31948 11 64185272-64204543 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 262.5;Syncytiotrophoblasts: 263.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017448, HPA039291, HPA044062" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 6300000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 67: Testis - Mixed function" "Cluster 55: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 75: Non-specific - Chaperones and protein folding" 148 "Plasma membrane, Cytosol" Nucleoplasm "CAB017448: , HPA039291: , HPA044062: " "unprognostic (6.73e-3)" "potential prognostic unfavorable (1.98e-4)" "unprognostic (2.89e-1)" "unprognostic (1.31e-2)" "unprognostic (1.47e-1)" "unprognostic (3.65e-2)" "unprognostic (8.15e-2)" "unprognostic (8.90e-2)" "potential prognostic unfavorable (5.43e-4)" "potential prognostic unfavorable (2.43e-4)" "unprognostic (7.10e-3)" "unprognostic (2.94e-1)" "potential prognostic unfavorable (6.56e-4)" "validated prognostic unfavorable (6.89e-11)" "validated prognostic unfavorable (2.35e-4)" "potential prognostic unfavorable (7.80e-5)" "unprognostic (3.00e-3)" "unprognostic (1.72e-2)" "unprognostic (2.60e-1)" "unprognostic (8.05e-2)" "unprognostic (3.70e-1)" "unprognostic (4.31e-2)" "potential prognostic unfavorable (2.25e-6)" "unprognostic (1.09e-2)" "unprognostic (7.47e-2)" "unprognostic (2.51e-1)" "unprognostic (3.57e-2)" "unprognostic (5.07e-2)" "unprognostic (1.70e-1)" "unprognostic (1.34e-1)" "unprognostic (9.41e-2)" STK10 "LOK, PRO2729" ENSG00000072786 "Serine/threonine kinase 10" O94804 5 172042079-172188224 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 72.3" "Cell type enhanced" "Detected in many" "cDC: 237.9;Kupffer cells: 494.0;Macrophages: 264.6;monocytes: 649.2;Neutrophil progenitors: 459.1;Neutrophils: 1534.1;NK-cells: 398.4;Sertoli cells: 269.6;T-cells: 277.0" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 173.1;leukocyte: 481.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Skin - Keratinocyte (granular), Spleen - T-cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015083, HPA015500, CAB020840" Enhanced Supported "Nucleoplasm,Nuclear bodies,Plasma membrane" NA NA 35000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 25: Non-specific - Transcription" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 8 "Plasma membrane" "Nucleoplasm, Nuclear bodies" "CAB020840: , HPA015083: , HPA015500: " "unprognostic (1.55e-1)" "unprognostic (7.85e-2)" "unprognostic (3.21e-2)" "unprognostic (2.70e-2)" "unprognostic (3.68e-1)" "unprognostic (2.95e-1)" "unprognostic (5.34e-2)" "unprognostic (3.29e-1)" "unprognostic (1.30e-1)" "unprognostic (1.09e-1)" "potential prognostic favorable (3.04e-4)" "unprognostic (3.24e-2)" "unprognostic (1.12e-1)" "unprognostic (1.18e-3)" "unprognostic (1.20e-2)" "unprognostic (2.11e-1)" "unprognostic (5.99e-2)" "potential prognostic unfavorable (5.57e-4)" "unprognostic (4.14e-1)" "unprognostic (1.04e-2)" "unprognostic (4.77e-2)" "unprognostic (4.00e-1)" "unprognostic (7.66e-3)" "unprognostic (2.66e-1)" "unprognostic (4.24e-2)" "unprognostic (2.08e-1)" "unprognostic (1.35e-1)" "unprognostic (8.61e-2)" "unprognostic (3.33e-2)" "unprognostic (1.19e-1)" "unprognostic (1.37e-2)" STK11 "LKB1, PJS" ENSG00000118046 "Serine/threonine kinase 11" Q15831 19 1177558-1228431 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Autophagy, Cell cycle, Differentiation, DNA damage, Spermatogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 142.1;Epicardial cells: 350.2;Late primary spermatocytes: 229.5;Late spermatids: 621.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 9.9" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016231, HPA017254, CAB022105, HPA067481" Approved Supported "Nucleoplasm,Primary cilium,Centrosome,Cytosol" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 67: Testis - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 23: Non-specific - Transcription" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 75 Nucleoplasm "Primary cilium, Centrosome, Cytosol" "CAB016231: , CAB022105: , HPA017254: , HPA067481: " "unprognostic (7.99e-2)" "unprognostic (2.13e-1)" "unprognostic (4.78e-2)" "unprognostic (1.91e-1)" "unprognostic (1.11e-1)" "unprognostic (2.11e-1)" "unprognostic (1.31e-1)" "unprognostic (1.27e-1)" "unprognostic (1.03e-3)" "unprognostic (2.56e-1)" "unprognostic (1.45e-3)" "unprognostic (1.35e-1)" "unprognostic (6.62e-2)" "unprognostic (2.48e-3)" "unprognostic (5.75e-3)" "unprognostic (1.26e-1)" "unprognostic (1.59e-1)" "unprognostic (1.27e-1)" "unprognostic (6.29e-2)" "unprognostic (2.62e-2)" "unprognostic (1.19e-1)" "unprognostic (2.01e-2)" "unprognostic (3.81e-2)" "unprognostic (1.41e-2)" "unprognostic (1.02e-2)" "unprognostic (2.53e-3)" "unprognostic (9.25e-2)" "unprognostic (9.37e-3)" "unprognostic (1.65e-1)" "unprognostic (2.81e-1)" "unprognostic (1.30e-3)" STK11IP "KIAA1898, LIP1, LKB1IP, STK11IP1" ENSG00000144589 "Serine/threonine kinase 11 interacting protein" Q8N1F8 2 219597857-219616451 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 38.8;Sertoli cells: 70.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 15.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036837, HPA036838, HPA053192" Approved Enhanced Vesicles NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 34: Non-specific - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 6 Vesicles "HPA036837: , HPA036838: , HPA053192: " "unprognostic (2.12e-1)" "unprognostic (8.69e-2)" "unprognostic (1.05e-2)" "unprognostic (2.69e-1)" "unprognostic (1.15e-1)" "unprognostic (1.35e-1)" "unprognostic (6.47e-2)" "unprognostic (2.87e-1)" "unprognostic (1.77e-2)" "unprognostic (6.37e-3)" "unprognostic (4.76e-1)" "unprognostic (1.09e-1)" "unprognostic (5.44e-2)" "potential prognostic unfavorable (1.85e-4)" "unprognostic (1.81e-1)" "unprognostic (1.20e-1)" "unprognostic (2.74e-2)" "unprognostic (7.39e-2)" "unprognostic (4.38e-2)" "unprognostic (1.95e-2)" "unprognostic (1.35e-2)" "unprognostic (1.16e-2)" "potential prognostic unfavorable (5.32e-5)" "unprognostic (6.03e-2)" "unprognostic (2.29e-1)" "unprognostic (9.95e-2)" "unprognostic (1.12e-1)" "potential prognostic favorable (3.03e-4)" "unprognostic (8.47e-3)" "unprognostic (2.43e-2)" "unprognostic (3.06e-1)" STK16 "MPSK, PKL12" ENSG00000115661 "Serine/threonine kinase 16" O75716 2 219245455-219250337 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 82.0;Late primary spermatocytes: 85.3;Late spermatids: 94.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029450 Approved Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Primary cilium,Primary cilium tip,Basal body,Cytosol" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 70: Non-specific - Protein processing" "Cluster 39: Astrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 102 Cytosol "Nucleoplasm, Nuclear bodies, Plasma membrane, Primary cilium, Primary cilium tip, Basal body" "HPA029450: " "unprognostic (1.67e-1)" "unprognostic (1.02e-1)" "unprognostic (3.15e-1)" "unprognostic (2.81e-1)" "unprognostic (2.54e-2)" "unprognostic (2.02e-2)" "unprognostic (5.07e-2)" "unprognostic (1.39e-1)" "unprognostic (7.31e-2)" "unprognostic (6.99e-2)" "potential prognostic favorable (1.48e-4)" "unprognostic (3.04e-3)" "unprognostic (5.82e-2)" "unprognostic (3.70e-3)" "unprognostic (8.15e-3)" "unprognostic (9.75e-2)" "unprognostic (6.74e-2)" "unprognostic (3.08e-1)" "unprognostic (4.74e-2)" "unprognostic (5.55e-2)" "unprognostic (1.50e-1)" "unprognostic (2.90e-1)" "unprognostic (4.01e-1)" "unprognostic (3.62e-1)" "unprognostic (3.72e-1)" "unprognostic (5.38e-2)" "unprognostic (3.23e-1)" "unprognostic (1.74e-1)" "unprognostic (1.19e-1)" "unprognostic (3.51e-1)" "unprognostic (1.15e-1)" STK17A DRAK1 ENSG00000164543 "Serine/threonine kinase 17a" Q9UEE5 7 43582758-43650713 "Enzymes, Plasma proteins, Predicted membrane proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 389.8;B-cells: 458.1;Neutrophils: 530.7;NK-cells: 459.5;Pancreatic duct cells: 385.0;T-cells: 479.3" "Group enriched" "Detected in all" 4 "Bergmann glia: 365.7;central nervous system macrophage: 179.4;leukocyte: 423.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "HPA018138, HPA037979" Uncertain Supported "Nuclear speckles,Plasma membrane" Yes No "Cluster 24: Non-specific - Transcription" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 2: Neurons - Nucleosome" "Cluster 67: Non-specific - Unknown function" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 1 "Nuclear speckles" "Plasma membrane" "HPA018138: , HPA037979: " "unprognostic (1.30e-1)" "unprognostic (5.74e-2)" "unprognostic (3.62e-1)" "unprognostic (2.34e-3)" "unprognostic (9.70e-3)" "unprognostic (1.23e-1)" "unprognostic (1.35e-1)" "unprognostic (1.47e-2)" "unprognostic (4.54e-2)" "unprognostic (7.11e-3)" "unprognostic (6.55e-2)" "unprognostic (2.72e-2)" "unprognostic (3.43e-1)" "unprognostic (3.30e-3)" "unprognostic (4.14e-1)" "unprognostic (5.62e-3)" "unprognostic (1.56e-3)" "unprognostic (2.10e-1)" "unprognostic (1.43e-1)" "unprognostic (2.09e-1)" "unprognostic (7.83e-2)" "unprognostic (4.22e-2)" "unprognostic (3.31e-2)" "unprognostic (8.48e-2)" "unprognostic (1.64e-1)" "unprognostic (1.85e-3)" "unprognostic (1.37e-1)" "unprognostic (2.88e-2)" "unprognostic (8.47e-3)" "unprognostic (9.46e-3)" "unprognostic (1.83e-1)" STK17B DRAK2 ENSG00000081320 "Serine/threonine kinase 17b" O94768 2 196133583-196176503 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 355.5;lymphoid tissue: 105.8" "Cell type enhanced" "Detected in many" "B-cells: 616.6;cDC: 761.5;Hematopoietic stem cells: 525.0;Innate lymphoid cells: 639.1;Mast cells: 789.8;Monocyte progenitors: 581.2;monocytes: 783.8;Neutrophil progenitors: 1111.7;Neutrophils: 3217.0;NK-cells: 616.6;T-cells: 869.4;Thymocytes: 653.8" "Cell type enriched" "Detected in many" 6 "leukocyte: 552.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "lymphoma: 74.3" "Testis - Early spermatids, Testis - Spermatocytes" "Region enriched" "Detected in all" 5 "cerebellum: 63.4" "Low region specificity" "Detected in all" "HPA034858, HPA073120" Enhanced Supported Nucleoplasm NA Yes "Cluster 35: Neutrophils - Protein binding" "Cluster 15: Bone marrow - Innate immune response" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 2 Nucleoplasm "HPA034858: , HPA073120: " "unprognostic (4.00e-2)" "unprognostic (2.13e-1)" "unprognostic (1.95e-1)" "unprognostic (4.30e-1)" "unprognostic (2.76e-1)" "unprognostic (1.71e-1)" "unprognostic (2.91e-1)" "unprognostic (2.16e-1)" "unprognostic (2.51e-3)" "unprognostic (2.07e-1)" "unprognostic (2.73e-2)" "unprognostic (1.42e-1)" "potential prognostic unfavorable (8.88e-5)" "unprognostic (2.44e-1)" "unprognostic (3.00e-1)" "unprognostic (2.23e-3)" "unprognostic (1.04e-2)" "unprognostic (6.65e-2)" "unprognostic (7.30e-2)" "unprognostic (2.04e-2)" "unprognostic (1.81e-1)" "unprognostic (7.49e-2)" "unprognostic (6.89e-3)" "unprognostic (4.06e-1)" "unprognostic (4.18e-2)" "unprognostic (6.79e-3)" "unprognostic (1.41e-2)" "unprognostic (2.98e-1)" "unprognostic (4.56e-2)" "unprognostic (5.11e-2)" "unprognostic (6.04e-2)" STK19 "D6S60, G11, RP1" ENSG00000204344 "Serine/threonine kinase 19" P49842 6 31971091-31982821 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 9.1;Bergmann glia: 11.6;Choroid plexus epithelial cells: 8.5;Distal convoluted tubule cells: 10.4;Early spermatids: 19.5;Ependymal cells: 9.4;Late spermatids: 22.0;Loop of henle epithelial cells: 11.1;Papillary tip epithelial cells: 11.5;Podocytes: 13.7;Proximal tubule cells: 19.2;Renal collecting duct intercalated cells: 9.2;Renal collecting duct principal cells: 12.1;Renal connecting tubule cells: 10.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 2.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Breast - Breast glandular cells, Breast - Breast glandular cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031511, HPA068559" Uncertain Supported "Nuclear speckles" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 55: Breast - Lactation" "Cluster 14: Neurons - Synaptic function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 105: Non-specific - Mixed function" 2 "Nuclear speckles" "HPA031511: , HPA068559: " "unprognostic (2.55e-2)" "unprognostic (4.89e-2)" "unprognostic (3.45e-1)" "unprognostic (1.16e-1)" "unprognostic (4.76e-3)" "unprognostic (5.91e-3)" "unprognostic (2.76e-2)" STK24 "MST-3, MST3, MST3B, STE20, STK3" ENSG00000102572 "Serine/threonine kinase 24" Q9Y6E0 13 98445185-98577940 "Enzymes, Predicted intracellular proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1281.0;Urothelial cells: 643.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026435, HPA026502" Enhanced Supported Nucleoli,Cytosol No No 610000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 103: Non-specific - Basic cellular processes" 57 "Nucleoli, Cytosol" "HPA026435: , HPA026502: " "unprognostic (1.00e-2)" "unprognostic (1.16e-1)" "unprognostic (3.45e-2)" "unprognostic (1.85e-2)" "unprognostic (1.40e-2)" "unprognostic (3.65e-2)" "unprognostic (4.64e-2)" "unprognostic (3.51e-1)" "unprognostic (6.86e-3)" "unprognostic (4.62e-3)" "validated prognostic favorable (2.66e-5)" "validated prognostic favorable (8.99e-8)" "unprognostic (6.96e-2)" "unprognostic (2.62e-3)" "potential prognostic unfavorable (7.75e-4)" "validated prognostic unfavorable (1.48e-5)" "validated prognostic unfavorable (3.20e-5)" "unprognostic (1.14e-2)" "unprognostic (2.52e-1)" "unprognostic (2.80e-1)" "unprognostic (4.75e-2)" "potential prognostic unfavorable (1.14e-4)" "unprognostic (6.05e-2)" "unprognostic (9.30e-2)" "unprognostic (4.36e-2)" "unprognostic (4.93e-2)" "unprognostic (1.44e-1)" "unprognostic (7.45e-2)" "unprognostic (2.89e-1)" "unprognostic (5.53e-2)" "unprognostic (1.16e-1)" STK25 "SOK1, YSK1" ENSG00000115694 "Serine/threonine kinase 25" O00506 2 241492670-241509730 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 459.7" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047147 Uncertain NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 51: Neurons - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 70 "HPA047147: " "unprognostic (4.44e-1)" "unprognostic (7.80e-2)" "potential prognostic favorable (4.79e-4)" "unprognostic (3.82e-3)" "unprognostic (7.09e-2)" "unprognostic (6.96e-2)" "unprognostic (4.19e-1)" "unprognostic (2.54e-1)" "unprognostic (7.60e-2)" "unprognostic (1.73e-1)" "potential prognostic favorable (6.66e-7)" "unprognostic (4.29e-2)" "unprognostic (5.44e-2)" "validated prognostic unfavorable (1.32e-9)" "validated prognostic unfavorable (8.33e-4)" "unprognostic (1.83e-3)" "unprognostic (1.38e-2)" "unprognostic (2.61e-1)" "unprognostic (2.33e-2)" "unprognostic (5.09e-2)" "unprognostic (5.13e-2)" "unprognostic (3.83e-2)" "unprognostic (1.81e-2)" "unprognostic (5.16e-1)" "unprognostic (2.62e-1)" "unprognostic (4.43e-3)" "unprognostic (1.03e-1)" "unprognostic (1.35e-1)" "unprognostic (2.34e-1)" "unprognostic (2.13e-2)" "unprognostic (3.83e-1)" STK26 "MASK, MST4" ENSG00000134602 "Serine/threonine kinase 26" Q9P289 X 132023302-132075943 "Enzymes, Predicted intracellular proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 66.1;epididymis: 53.1" "Cell type enhanced" "Detected in many" "Innate lymphoid cells: 85.4;Monocyte progenitors: 101.8;Neutrophil progenitors: 191.6;Neutrophils: 185.9;Ocular epithelial cells: 83.1;Thymocytes: 101.6" "Cell type enhanced" "Detected in many" "leukocyte: 72.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Breast - Breast myoepithelial cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA059921 Approved Uncertain "Nucleoplasm,Golgi apparatus,Centrosome,Cytosol" Yes No 270000 "Cluster 32: Basophils - Transcription" "Cluster 22: Epididymis - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 36: Non-specific - mRNA processing" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 81 Nucleoplasm "Golgi apparatus, Centrosome, Cytosol" "HPA059921: " "unprognostic (2.45e-1)" "unprognostic (4.29e-2)" "unprognostic (4.73e-2)" "unprognostic (9.41e-2)" "unprognostic (1.55e-1)" "unprognostic (9.40e-2)" "unprognostic (1.31e-1)" "unprognostic (3.46e-2)" "unprognostic (8.20e-3)" "unprognostic (1.52e-2)" "unprognostic (2.73e-2)" "potential prognostic unfavorable (8.03e-5)" "unprognostic (2.21e-3)" "unprognostic (7.80e-3)" "unprognostic (3.30e-1)" "unprognostic (8.23e-2)" "unprognostic (2.50e-1)" "unprognostic (4.34e-1)" "unprognostic (1.47e-1)" "unprognostic (1.46e-3)" "unprognostic (2.45e-1)" "unprognostic (4.51e-1)" "unprognostic (1.42e-1)" "unprognostic (6.43e-2)" "unprognostic (5.88e-2)" "unprognostic (1.02e-1)" "unprognostic (1.93e-1)" "unprognostic (2.89e-1)" "unprognostic (9.39e-2)" STK3 "KRS1, MST2" ENSG00000104375 "Serine/threonine kinase 3" Q13188 8 98371228-98942827 "Enzymes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 4 "dendritic cells: 7.8;granulocytes: 8.8;monocytes: 8.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007120, CAB025316, HPA073281" Approved Approved "Intermediate filaments,Rods & Rings" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 75: Ovary - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 40: Non-specific - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" 87 "Intermediate filaments, Rods & Rings" "CAB025316: , HPA007120: , HPA073281: " "unprognostic (6.12e-2)" "potential prognostic unfavorable (6.91e-4)" "unprognostic (2.78e-1)" "unprognostic (4.50e-2)" "unprognostic (2.74e-1)" "potential prognostic unfavorable (7.13e-4)" "unprognostic (1.86e-1)" "unprognostic (1.70e-1)" "unprognostic (5.79e-3)" "unprognostic (3.73e-2)" "unprognostic (7.91e-3)" "unprognostic (1.54e-2)" "unprognostic (5.39e-2)" "unprognostic (1.24e-2)" "unprognostic (6.31e-2)" "unprognostic (2.89e-3)" "unprognostic (1.28e-1)" "unprognostic (5.86e-2)" "unprognostic (1.03e-1)" "unprognostic (6.06e-3)" "potential prognostic unfavorable (9.19e-4)" "potential prognostic unfavorable (2.19e-4)" "unprognostic (4.43e-3)" "unprognostic (3.82e-1)" "unprognostic (6.20e-2)" "unprognostic (1.07e-1)" "unprognostic (4.75e-2)" "unprognostic (8.04e-2)" "unprognostic (2.22e-1)" "unprognostic (8.93e-2)" "unprognostic (5.00e-2)" STK31 "SgK396, TDRD8" ENSG00000196335 "Serine/threonine kinase 31" Q9BXU1 7 23710203-23832513 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 43 "testis: 59.9" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 36.4;Early primary spermatocytes: 130.3;Late primary spermatocytes: 306.5;Oocytes: 105.9;Retinal pigment epithelial cells: 55.4;Undifferentiated spermatogonia: 182.9" "Cell type enhanced" "Detected in many" "oligodendrocyte: 37.5" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 4.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 1.7;Gastric cancer: 2.2" "Testis - Early spermatids, Testis - Spermatocytes" "Not detected" "Not detected" "HPA023194, HPA072896" Enhanced NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 25: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" "HPA023194: , HPA072896: " "unprognostic (2.70e-1)" "unprognostic (4.89e-2)" "unprognostic (4.82e-2)" "unprognostic (2.06e-3)" "unprognostic (2.96e-1)" "unprognostic (1.88e-1)" "unprognostic (2.62e-1)" "unprognostic (2.52e-1)" "unprognostic (4.70e-3)" "unprognostic (1.51e-1)" "unprognostic (1.31e-1)" STK32A "MGC22688, YANK1" ENSG00000169302 "Serine/threonine kinase 32A" Q8WU08 5 147234963-147387855 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 10.6;brain: 11.3;thyroid gland: 8.1" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 102.9;Adrenal medulla cells: 117.0;Astrocytes: 118.7;Bergmann glia: 844.6;Distal convoluted tubule cells: 100.9;Ependymal cells: 161.1;Melanocytes: 107.1;Oligodendrocyte progenitor cells: 467.5;Pituicytes/FSCs: 473.9;Schwann cells: 118.9" "Cell type enhanced" "Detected in many" "Bergmann glia: 917.1;oligodendrocyte precursor cell: 533.6" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 25.6;Thyroid Carcinoma (TCGA): 14.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 9.6" "Breast - Fibroblasts, Colon - Enteric glia cells, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040236 Approved Centrosome NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 1 Centrosome "HPA040236: " "unprognostic (6.09e-2)" "unprognostic (2.67e-1)" "unprognostic (9.72e-3)" "potential prognostic unfavorable (6.39e-4)" "unprognostic (1.89e-1)" "unprognostic (2.41e-2)" "potential prognostic favorable (7.66e-4)" "unprognostic (3.74e-1)" "unprognostic (1.28e-2)" "unprognostic (6.32e-2)" "unprognostic (4.34e-1)" "unprognostic (1.01e-1)" "unprognostic (5.05e-2)" STK32B "HSA250839, STK32, STKG6, YANK2" ENSG00000152953 "Serine/threonine kinase 32B" Q9NY57 4 5051480-5500994 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 14.0;lymphoid tissue: 18.1" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 271.6;Early spermatids: 244.2;Epicardial cells: 129.6;Fibro-adipogenic progenitors: 203.7;Hematopoietic stem cells: 105.8;Loop of henle epithelial cells: 298.7;Lymphatic endothelial cells: 271.8;Microglia: 131.3;Mucous neck cells: 120.5;Oligodendrocyte progenitor cells: 293.8;Oocytes: 142.8;Pancreatic islet cells: 127.7;Proximal tubule cells: 177.1;Thymocytes: 192.3" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 199.2;committed oligodendrocyte precursor: 170.8;oligodendrocyte precursor cell: 421.9" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 18.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 31.6;skin cancer: 22.2" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Lung - Fibroblasts_2, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA015820 Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 69: Skin cancer - ECM organization" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" "Nucleoplasm, Nuclear bodies" Cytosol "HPA015820: " "unprognostic (5.39e-2)" "unprognostic (1.71e-1)" "unprognostic (2.07e-2)" "unprognostic (1.89e-3)" "unprognostic (4.43e-3)" "unprognostic (1.66e-2)" "unprognostic (3.76e-3)" "validated prognostic favorable (2.37e-12)" "validated prognostic favorable (1.53e-4)" "potential prognostic favorable (7.59e-6)" "unprognostic (2.42e-2)" "unprognostic (5.27e-3)" "unprognostic (5.46e-2)" "unprognostic (1.44e-1)" "unprognostic (9.37e-2)" "unprognostic (1.54e-1)" "unprognostic (3.37e-1)" "unprognostic (2.44e-2)" "unprognostic (1.28e-1)" "unprognostic (8.10e-2)" "unprognostic (3.74e-3)" "unprognostic (2.61e-1)" "unprognostic (5.63e-2)" STK32C "MGC23665, PKE, YANK3" ENSG00000165752 "Serine/threonine kinase 32C" Q86UX6 10 132207492-132331847 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 46.3;testis: 51.6" "Cell type enhanced" "Detected in many" "Early spermatids: 304.9;Epididymal principal cells: 98.0;Late primary spermatocytes: 253.2;Late spermatids: 88.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 55.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017894 Uncertain NA NA "Cluster 41: Basophils - Unknown function" "Cluster 78: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 6 "HPA017894: " "unprognostic (3.58e-2)" "unprognostic (1.13e-1)" "unprognostic (5.78e-2)" "unprognostic (3.72e-2)" "unprognostic (1.59e-3)" "unprognostic (9.15e-2)" "unprognostic (2.08e-3)" "unprognostic (8.91e-3)" "unprognostic (1.24e-1)" "unprognostic (1.67e-2)" "unprognostic (1.83e-3)" "potential prognostic unfavorable (7.10e-7)" "unprognostic (1.43e-1)" "potential prognostic unfavorable (2.66e-5)" "unprognostic (2.45e-2)" "unprognostic (6.36e-2)" "unprognostic (2.49e-1)" "unprognostic (1.85e-1)" "unprognostic (6.36e-2)" "unprognostic (9.68e-2)" "unprognostic (1.01e-1)" "unprognostic (3.13e-2)" "unprognostic (1.83e-1)" "unprognostic (2.23e-1)" "unprognostic (9.28e-3)" "unprognostic (1.33e-3)" "unprognostic (1.74e-2)" "unprognostic (5.40e-2)" "unprognostic (1.43e-1)" "unprognostic (2.31e-1)" "unprognostic (1.45e-2)" STK33 ENSG00000130413 "Serine/threonine kinase 33" Q9BYT3 11 8391868-8594289 "Enzymes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 38.3;testis: 45.2" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 1463.7;Corticotrophs: 1775.2;Endometrial ciliated cells: 1020.0;Ependymal cells: 1207.5;Fallopian tube ciliated cells: 1056.1;Pituicytes/FSCs: 608.2;Respiratory ciliated cells: 2154.5;Somatotrophs: 668.6;Thyrotrophs: 743.1" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 1194.0;ependymal cell: 1309.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory B-cell: 3.4;naive B-cell: 2.0" "Lineage enriched" "Detected in single" 5 "B-cells: 3.4" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Spleen - B-cells (Spleen), Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA015742, HPA056855" Uncertain Approved "Nucleoplasm,Nucleoli,Cytosol,Flagellar centriole,Mid piece" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 65: Non-specific - Unknown function" "Cluster 107: Ciliated cells - Cilia assembly & function" 8 "Nucleoplasm, Flagellar centriole" "Nucleoli, Cytosol, Mid piece" "HPA015742: , HPA056855: " "unprognostic (2.35e-1)" "unprognostic (3.34e-2)" "unprognostic (4.96e-1)" "unprognostic (8.89e-3)" "unprognostic (4.71e-2)" "unprognostic (2.17e-1)" "unprognostic (2.18e-1)" "unprognostic (5.01e-2)" "unprognostic (7.01e-2)" "unprognostic (1.18e-1)" "unprognostic (3.81e-2)" "potential prognostic favorable (5.51e-5)" "unprognostic (6.66e-2)" "unprognostic (1.69e-2)" "unprognostic (1.28e-1)" "unprognostic (7.30e-2)" "unprognostic (1.75e-1)" "unprognostic (5.47e-2)" "unprognostic (2.51e-3)" "unprognostic (7.07e-2)" "unprognostic (1.29e-1)" "unprognostic (4.62e-2)" "unprognostic (3.87e-1)" "unprognostic (1.80e-1)" "unprognostic (2.09e-2)" STK35 "bA550O8.2, CLIK1" ENSG00000125834 "Serine/threonine kinase 35" Q8TDR2 20 2101827-2177038 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "retina: 110.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 358.1;Early spermatids: 269.2;Late spermatids: 1510.5;Müller glia: 692.7;Retinal amacrine cells: 245.4;Retinal bipolar cells: 210.9;Retinal horizontal cells: 370.6;Rod photoreceptor cells: 248.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026452, HPA051673" Approved Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 42: Retina - Visual perception" "Cluster 38: Sub-cortical - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 11: Muller glia cells - Retinal homeostasis" 19 "Nucleoplasm, Nuclear bodies" "HPA026452: , HPA051673: " "unprognostic (6.74e-2)" "unprognostic (1.82e-2)" "unprognostic (5.61e-2)" "unprognostic (2.53e-2)" "unprognostic (1.57e-1)" "unprognostic (2.09e-3)" "unprognostic (2.48e-1)" "unprognostic (2.42e-2)" "unprognostic (1.42e-1)" "unprognostic (2.25e-1)" "unprognostic (1.55e-1)" "unprognostic (3.92e-1)" "unprognostic (5.32e-2)" "potential prognostic unfavorable (4.97e-5)" "unprognostic (4.49e-2)" "unprognostic (2.38e-2)" "unprognostic (1.01e-2)" "unprognostic (3.98e-3)" "unprognostic (1.28e-1)" "unprognostic (2.76e-2)" "unprognostic (2.15e-1)" "unprognostic (2.00e-1)" "unprognostic (7.98e-2)" "unprognostic (1.51e-1)" "unprognostic (5.67e-2)" "unprognostic (3.43e-2)" "unprognostic (1.11e-1)" "unprognostic (1.74e-1)" "unprognostic (2.39e-1)" "unprognostic (2.41e-2)" "unprognostic (1.23e-1)" STK36 "FU, KIAA1278" ENSG00000163482 "Serine/threonine kinase 36" Q9NRP7 2 218672069-218702716 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Ciliopathy, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 36.2;Ependymal cells: 43.9;Respiratory ciliated cells: 49.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027409, HPA027453, HPA030058" Approved Supported Cytosol NA NA "Cluster 21: Testis - Mixed function" "Cluster 17: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" 15 Cytosol "HPA027409: , HPA027453: , HPA030058: " "unprognostic (8.78e-2)" "unprognostic (7.10e-2)" "unprognostic (6.66e-3)" "unprognostic (1.36e-1)" "unprognostic (1.83e-1)" "unprognostic (4.05e-2)" "unprognostic (2.29e-1)" "unprognostic (2.27e-1)" "unprognostic (1.19e-2)" "unprognostic (1.81e-1)" "unprognostic (1.19e-2)" "unprognostic (1.23e-1)" "unprognostic (3.33e-2)" "unprognostic (4.68e-3)" "unprognostic (2.62e-1)" "unprognostic (8.71e-2)" "unprognostic (1.38e-1)" "unprognostic (1.55e-1)" "unprognostic (2.63e-1)" "unprognostic (1.09e-1)" "unprognostic (5.30e-3)" "unprognostic (1.55e-1)" "unprognostic (7.69e-3)" "unprognostic (1.70e-1)" "unprognostic (1.54e-2)" "unprognostic (1.22e-2)" "unprognostic (2.67e-1)" "unprognostic (5.00e-2)" "unprognostic (1.52e-1)" "unprognostic (7.82e-3)" "unprognostic (1.75e-1)" STK38 "NDR, NDR1" ENSG00000112079 "Serine/threonine kinase 38" Q15208 6 36493892-36547479 "Enzymes, Predicted intracellular proteins" "DNA damage" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophil progenitors: 496.7;Neutrophils: 601.2" "Cell type enhanced" "Detected in all" "leukocyte: 384.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004673, HPA038623, HPA051324" Uncertain Supported Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 5: Spleen - Immune response" "Cluster 25: Non-specific - Transcription" "Cluster 6: Leukemia - Signal transduction" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 43 Cytosol "CAB004673: , HPA038623: , HPA051324: " "unprognostic (1.67e-1)" "unprognostic (5.30e-3)" "unprognostic (3.65e-1)" "unprognostic (1.16e-1)" "unprognostic (1.10e-1)" "unprognostic (1.08e-1)" "unprognostic (3.60e-1)" "unprognostic (3.62e-2)" "unprognostic (4.00e-2)" "potential prognostic unfavorable (1.68e-4)" "unprognostic (5.76e-3)" "unprognostic (5.24e-2)" "unprognostic (8.54e-2)" "unprognostic (2.11e-3)" "unprognostic (1.88e-1)" "unprognostic (2.70e-2)" "unprognostic (6.39e-2)" "unprognostic (1.50e-2)" "unprognostic (2.19e-1)" "unprognostic (1.95e-1)" "unprognostic (5.94e-2)" "unprognostic (3.79e-2)" "unprognostic (1.17e-1)" "unprognostic (8.09e-3)" "potential prognostic favorable (3.60e-5)" "unprognostic (1.82e-1)" "potential prognostic unfavorable (7.81e-4)" "unprognostic (2.40e-1)" "unprognostic (2.32e-1)" "unprognostic (1.21e-1)" "unprognostic (2.29e-2)" STK38L "KIAA0965, NDR2" ENSG00000211455 "Serine/threonine kinase 38 like" Q9Y2H1 12 27243968-27325959 "Enzymes, Predicted intracellular proteins" "Actin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 80.0" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 396.5;Neutrophil progenitors: 308.5;Neutrophils: 655.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "dendritic cells: 49.9;granulocytes: 81.2;monocytes: 33.1" "Low cancer specificity" "Detected in all" "Lung - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038623, HPA051324" Approved Supported Cytosol NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 55: Lymphoma - Immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 22 Cytosol "HPA038623: , HPA051324: " "unprognostic (1.93e-1)" "unprognostic (7.73e-2)" "unprognostic (3.33e-1)" "unprognostic (2.38e-2)" "unprognostic (4.27e-1)" "unprognostic (9.02e-2)" "unprognostic (6.21e-2)" "unprognostic (7.94e-3)" "unprognostic (1.27e-1)" "unprognostic (1.61e-1)" "potential prognostic favorable (4.85e-4)" "unprognostic (6.30e-3)" "unprognostic (3.02e-1)" "unprognostic (8.67e-3)" "unprognostic (3.90e-2)" "unprognostic (1.16e-2)" "unprognostic (3.96e-3)" "unprognostic (1.34e-1)" "unprognostic (1.56e-1)" "unprognostic (4.18e-2)" "unprognostic (2.56e-1)" "unprognostic (2.26e-3)" "unprognostic (1.69e-1)" "unprognostic (6.68e-2)" "unprognostic (1.67e-2)" "unprognostic (3.01e-1)" "unprognostic (2.53e-2)" "unprognostic (8.49e-2)" "unprognostic (2.73e-1)" "unprognostic (2.87e-2)" "unprognostic (2.14e-1)" STK39 "DCHT, SPAK" ENSG00000198648 "Serine/threonine kinase 39" Q9UEW8 2 167954020-168247595 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 2338.2;Conjunctival goblet cells: 860.2;Lacrimal acinar cells: 2352.4;Pituicytes/FSCs: 932.7;Pituitary stem cells: 861.1;Salivary ionocytes: 1567.3" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 1901.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046022, HPA061803, HPA062802" Enhanced Supported Nucleoplasm,Vesicles,Cytosol NA NA 43000 "Cluster 15: NK-cells - Unknown function" "Cluster 60: Stomach - Digestion" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 11 Nucleoplasm "Vesicles, Cytosol" "CAB046022: , HPA061803: , HPA062802: " "unprognostic (1.09e-1)" "unprognostic (9.82e-2)" "unprognostic (1.79e-1)" "unprognostic (3.96e-1)" "unprognostic (7.02e-2)" "unprognostic (1.98e-1)" "unprognostic (3.91e-1)" "unprognostic (1.31e-2)" "unprognostic (2.25e-1)" "unprognostic (3.99e-2)" "unprognostic (7.04e-2)" "unprognostic (1.19e-2)" "unprognostic (8.87e-2)" "potential prognostic unfavorable (4.21e-4)" "unprognostic (1.83e-2)" "unprognostic (1.95e-1)" "unprognostic (1.47e-1)" "unprognostic (1.87e-1)" "unprognostic (1.05e-1)" "unprognostic (2.85e-2)" "unprognostic (1.65e-1)" "unprognostic (8.89e-3)" "unprognostic (2.37e-1)" "unprognostic (5.56e-2)" "unprognostic (6.67e-2)" "unprognostic (1.76e-1)" "unprognostic (7.46e-2)" "unprognostic (7.51e-2)" "unprognostic (2.06e-2)" "unprognostic (3.21e-1)" "unprognostic (1.27e-1)" STK4 "KRS2, MST1, YSK3" ENSG00000101109 "Serine/threonine kinase 4" Q13043 20 44966494-45080021 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 46.4;lymphoid tissue: 36.6" "Cell type enhanced" "Detected in all" "B-cells: 579.1;cDC: 653.6;Mast cells: 467.2;Neutrophil progenitors: 625.0;Neutrophils: 1741.0;NK-cells: 610.9;Plasma cells: 411.8;Platelets: 437.0;T-cells: 762.3" "Group enriched" "Detected in all" 4 "central nervous system macrophage: 321.7;leukocyte: 640.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004038, HPA015270" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 25000 "Cluster 35: Neutrophils - Protein binding" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 7: Non-specific - Ribosome" "Cluster 55: Lymphoma - Immune response" "Cluster 82: Dendritic cells - Antigen presentation" 1018 "Nuclear bodies" "Nucleoplasm, Cytosol" "CAB004038: , HPA015270: " "unprognostic (2.08e-3)" "unprognostic (1.25e-1)" "unprognostic (7.24e-2)" "unprognostic (6.45e-2)" "unprognostic (5.37e-2)" "unprognostic (3.16e-2)" "unprognostic (2.77e-2)" "unprognostic (2.25e-2)" "unprognostic (1.23e-1)" "potential prognostic unfavorable (3.27e-4)" "unprognostic (4.02e-2)" "unprognostic (6.35e-2)" "unprognostic (1.73e-2)" "potential prognostic unfavorable (1.51e-5)" "unprognostic (7.54e-2)" "unprognostic (9.17e-2)" "unprognostic (2.47e-1)" "unprognostic (5.90e-3)" "unprognostic (2.38e-1)" "unprognostic (6.33e-2)" "potential prognostic unfavorable (4.65e-4)" "unprognostic (2.49e-1)" "potential prognostic unfavorable (8.24e-5)" "unprognostic (1.58e-2)" "unprognostic (2.37e-2)" "unprognostic (2.18e-3)" "unprognostic (2.67e-1)" "unprognostic (9.02e-2)" "unprognostic (1.83e-1)" "unprognostic (3.04e-2)" "unprognostic (1.20e-1)" STK40 "MGC4796, SgK495" ENSG00000196182 "Serine/threonine kinase 40" Q8N2I9 1 36339624-36385924 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 337.6;Late spermatids: 382.6;Neutrophils: 691.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 25.3" "Group enriched" "Detected in all" 5 "granulocytes: 25.3;monocytes: 12.0" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008026 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 24: Non-specific - Transcription" "Cluster 44: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 12 Cytosol Nucleoplasm "HPA008026: " "unprognostic (3.76e-2)" "unprognostic (2.77e-1)" "unprognostic (1.71e-1)" "unprognostic (8.46e-2)" "unprognostic (1.20e-1)" "unprognostic (7.75e-2)" "unprognostic (1.67e-1)" "unprognostic (1.84e-2)" "unprognostic (9.12e-2)" "unprognostic (2.07e-1)" "potential prognostic favorable (8.76e-4)" "unprognostic (7.36e-3)" "unprognostic (7.28e-2)" "potential prognostic unfavorable (2.19e-4)" "unprognostic (1.59e-1)" "unprognostic (5.48e-2)" "unprognostic (3.13e-1)" "unprognostic (3.22e-2)" "unprognostic (3.52e-2)" "unprognostic (1.16e-2)" "unprognostic (4.03e-1)" "potential prognostic favorable (1.36e-4)" "unprognostic (7.90e-2)" "unprognostic (1.53e-1)" "unprognostic (4.15e-1)" "unprognostic (1.21e-1)" "unprognostic (3.92e-1)" "unprognostic (1.32e-1)" "unprognostic (2.72e-1)" "unprognostic (5.56e-2)" "unprognostic (3.16e-1)" STKLD1 "C9orf96, MGC43306, SGK071" ENSG00000198870 "Serine/threonine kinase like domain containing 1" Q8NE28 9 133376366-133406096 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 16 "testis: 9.4" "Cell type enriched" "Detected in some" 4 "Late spermatids: 65.9" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA029902 Uncertain NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 37: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" "HPA029902: " "unprognostic (1.38e-2)" "unprognostic (3.43e-2)" "unprognostic (4.26e-1)" STMN1 "C1orf215, FLJ32206, Lag, LAP18, OP18, PP17, PP19, PR22, SMN" ENSG00000117632 "Stathmin 1" P16949 1 25884181-25906991 "Cancer-related genes, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1366.8;lymphoid tissue: 1250.2" "Cell type enhanced" "Detected in all" "Early primary spermatocytes: 676.5;Early spermatids: 1053.3;Extravillous trophoblasts: 691.8;Granulosa cells: 978.1;Hofbauer cells: 864.3;Late primary spermatocytes: 943.7;Late spermatids: 3456.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 425.4" "Group enriched" "Detected in all" 5 "dendritic cells: 425.4;T-cells: 143.7" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Kidney - Fibroblasts, Minor Salivary Gland - Mitotic cells (Minor salivary gland), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010107, HPA068438" Enhanced Approved Cytosol NA NA 990000 "Cluster 13: Non-specific - Mitochondria" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 53: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 27: Non-specific - Cell proliferation" 20 Cytosol "CAB010107: , HPA068438: " "unprognostic (1.21e-1)" "unprognostic (1.26e-1)" "unprognostic (1.92e-2)" "unprognostic (2.79e-2)" "unprognostic (8.81e-2)" "unprognostic (1.83e-1)" "unprognostic (7.86e-2)" "potential prognostic favorable (1.58e-4)" "unprognostic (3.13e-2)" "potential prognostic unfavorable (3.53e-5)" "unprognostic (7.93e-3)" "unprognostic (6.47e-2)" "unprognostic (2.22e-1)" "validated prognostic unfavorable (7.94e-7)" "validated prognostic unfavorable (5.14e-6)" "unprognostic (6.81e-2)" "unprognostic (2.99e-2)" "unprognostic (2.09e-3)" "unprognostic (2.53e-2)" "unprognostic (7.94e-2)" "unprognostic (4.68e-1)" "unprognostic (9.91e-2)" "unprognostic (6.85e-3)" "unprognostic (1.26e-2)" "unprognostic (4.55e-2)" "unprognostic (1.77e-2)" "unprognostic (2.11e-2)" "unprognostic (2.80e-1)" "unprognostic (8.70e-2)" "unprognostic (2.31e-1)" "unprognostic (2.50e-2)" STMN2 "SCG10, SCGN10" ENSG00000104435 "Stathmin 2" Q93045 8 79611117-79666158 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 576.2" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 95.7;Brain excitatory neurons: 367.1;Brain inhibitory neurons: 191.3;Corticotrophs: 72.9;Other brain neurons: 559.9;Pancreatic islet cells: 165.2;Retinal amacrine cells: 74.3;Retinal ganglion cells: 104.3;Retinal horizontal cells: 132.2" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Glioblastoma Multiforme (TCGA): 55.7;Pancreatic Adenocarcinoma (TCGA): 20.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 13 "plasmacytoid DC: 2.2" "Lineage enriched" "Detected in single" 13 "dendritic cells: 2.2" "Cancer enriched" "Detected in many" 33 "Neuroblastoma: 399.3" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026922 Approved "Endoplasmic reticulum,Vesicles" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 27: Cerebellum - Synaptic function" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 98: Neurons - Neurotransmission & signaling" 31 Vesicles "Endoplasmic reticulum" "HPA026922: " "unprognostic (1.14e-1)" "unprognostic (2.47e-1)" "unprognostic (2.08e-2)" "unprognostic (9.32e-2)" "unprognostic (2.27e-2)" "unprognostic (1.44e-1)" "unprognostic (1.02e-1)" "unprognostic (1.14e-2)" "unprognostic (4.00e-2)" "potential prognostic unfavorable (5.74e-4)" "unprognostic (6.34e-2)" "unprognostic (3.91e-2)" "unprognostic (3.99e-1)" "unprognostic (2.00e-3)" "unprognostic (2.80e-2)" "unprognostic (2.91e-1)" "unprognostic (7.28e-2)" "unprognostic (8.39e-2)" "unprognostic (3.99e-1)" "unprognostic (1.09e-1)" "unprognostic (1.01e-1)" "unprognostic (1.09e-1)" "unprognostic (6.16e-2)" "unprognostic (2.56e-1)" "unprognostic (9.67e-3)" "unprognostic (2.82e-2)" STMN3 SCLIP ENSG00000197457 "Stathmin 3" Q9NZ72 20 63639705-63657682 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 337.2" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 63.8;Brain excitatory neurons: 91.4;Brain inhibitory neurons: 90.1;Granulosa cells: 76.2;Other brain neurons: 120.0;Retinal amacrine cells: 96.3;Retinal bipolar cells: 72.3;Retinal ganglion cells: 69.5;Retinal horizontal cells: 68.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Lineage enriched" "Detected in many" 5 "T-cells: 6.2" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Skeletal muscle - Fibroblasts, Skin - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012947 Enhanced Supported "Golgi apparatus,Cytosol" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 24: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 98: Neurons - Neurotransmission & signaling" 25 "Golgi apparatus" Cytosol "HPA012947: " "potential prognostic favorable (1.37e-4)" "unprognostic (1.66e-1)" "unprognostic (4.00e-1)" "unprognostic (1.04e-2)" "unprognostic (3.79e-2)" "unprognostic (1.02e-1)" "unprognostic (3.99e-3)" "unprognostic (1.28e-1)" "unprognostic (1.09e-1)" "unprognostic (3.98e-1)" "unprognostic (1.67e-1)" "unprognostic (5.41e-1)" "unprognostic (5.05e-2)" "unprognostic (2.48e-1)" "unprognostic (4.22e-2)" "unprognostic (3.01e-1)" "unprognostic (1.25e-1)" "unprognostic (1.50e-1)" "unprognostic (1.52e-1)" "unprognostic (1.82e-2)" "unprognostic (1.57e-1)" "unprognostic (1.57e-3)" "potential prognostic unfavorable (2.31e-8)" "unprognostic (5.73e-2)" "unprognostic (9.84e-2)" "unprognostic (2.08e-2)" "unprognostic (7.32e-2)" "unprognostic (1.60e-1)" "unprognostic (2.60e-1)" "unprognostic (1.85e-2)" "unprognostic (1.86e-1)" STMN4 RB3 ENSG00000015592 "Stathmin 4" Q9H169 8 27235308-27258420 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "brain: 426.0" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 41.1;Brain inhibitory neurons: 34.5;Oligodendrocyte progenitor cells: 52.9;Oligodendrocytes: 234.7;Other brain neurons: 41.9;Retinal amacrine cells: 47.9;Retinal bipolar cells: 26.8;Retinal ganglion cells: 34.8;Retinal horizontal cells: 66.1" "Cell type enriched" "Detected in all" 4 "oligodendrocyte: 365.0" "Cancer enriched" "Detected in some" 27 "Glioblastoma Multiforme (TCGA): 63.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Neuroblastoma: 60.8" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027765 Uncertain "Golgi apparatus,Vesicles" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 80: Oligodendrocytes - Myelination" 1 "Golgi apparatus" Vesicles "HPA027765: " "unprognostic (4.92e-3)" "unprognostic (7.20e-2)" "potential prognostic favorable (3.73e-4)" "unprognostic (3.12e-1)" "potential prognostic favorable (7.19e-4)" "unprognostic (1.47e-1)" STMND1 FLJ23152 ENSG00000230873 "Stathmin domain containing 1" H3BQB6 6 17102050-17131378 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 7.7;fallopian tube: 16.7" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 31.1;Early primary spermatocytes: 29.6;Endometrial ciliated cells: 143.6;Epididymal efferent duct ciliated cells: 98.6;Fallopian tube ciliated cells: 161.0;Respiratory ciliated cells: 315.8;Respiratory deuterosomal cells: 57.0;Sertoli cells: 50.6" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 18.0;ependymal cell: 25.9" "Group enriched" "Detected in some" 4 "Breast Invasive Carcinoma (TCGA): 12.6;Uterine Corpus Endometrial Carcinoma (TCGA): 5.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "breast cancer: 3.2" "Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Testis - Sertoli cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA067970 Enhanced Approved "Actin filaments" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 27: Breast cancer - Unknown function" "Cluster 107: Ciliated cells - Cilia assembly & function" "Actin filaments" "HPA067970: " "unprognostic (1.31e-1)" "unprognostic (3.95e-2)" "unprognostic (2.79e-2)" "unprognostic (6.38e-2)" "unprognostic (2.00e-3)" "unprognostic (1.20e-2)" "unprognostic (6.66e-2)" "unprognostic (1.53e-1)" "unprognostic (2.64e-1)" STMP1 "C7orf73, Mm47, PL-5283" ENSG00000243317 "Short transmembrane mitochondrial protein 1" E0CX11 7 135662496-135693418 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 2119.3;Esophageal suprabasal cells: 739.7;Late spermatids: 1997.6;Platelets: 569.1" "Cell type enriched" "Detected in all" 4 "choroid plexus epithelial cell: 393.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 433.1;eosinophil: 127.9" "Lineage enriched" "Detected in all" 6 "granulocytes: 433.1" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065565 Approved Mitochondria "Intracellular and membrane" Immunity NA NA "Cluster 41: Basophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 39: Non-specific - Transcription" "Cluster 85: Squamous epithelial cells - Keratinization" 1 Mitochondria "HPA065565: " "unprognostic (3.84e-1)" "unprognostic (4.30e-2)" "unprognostic (5.38e-2)" "unprognostic (1.47e-2)" "unprognostic (1.62e-1)" "unprognostic (6.80e-2)" "unprognostic (7.74e-3)" "unprognostic (2.20e-1)" "unprognostic (1.46e-2)" "unprognostic (3.03e-2)" "unprognostic (8.39e-3)" "unprognostic (9.70e-2)" "potential prognostic unfavorable (1.18e-4)" "unprognostic (1.29e-3)" "unprognostic (1.41e-1)" "unprognostic (3.35e-2)" "unprognostic (1.77e-1)" "unprognostic (1.11e-2)" "unprognostic (3.34e-2)" "unprognostic (1.19e-1)" "unprognostic (2.38e-2)" "unprognostic (2.13e-1)" "unprognostic (1.66e-1)" "unprognostic (3.66e-1)" "unprognostic (2.34e-1)" "unprognostic (1.95e-2)" "unprognostic (1.75e-1)" "unprognostic (1.03e-2)" "unprognostic (5.68e-2)" STN1 "bA541N10.2, FLJ22559, OBFC1" ENSG00000107960 "STN1 subunit of CST complex" Q9H668 10 103856806-103918332 "Disease related genes, Human disease related genes, Predicted intracellular proteins" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 13.7;Bergmann glia: 14.6;Brain inhibitory neurons: 11.9;Choroid plexus epithelial cells: 30.3;Distal convoluted tubule cells: 39.0;Ependymal cells: 16.4;Loop of henle epithelial cells: 18.3;Microglia: 20.1;Oligodendrocytes: 18.7;Other brain neurons: 14.9;Papillary tip epithelial cells: 53.3;Podocytes: 63.2;Renal collecting duct intercalated cells: 13.7;Renal collecting duct principal cells: 22.4;Renal connecting tubule cells: 24.8" "Cell type enhanced" "Detected in all" "leukocyte: 78.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037924, HPA037925" Supported Nucleoplasm NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 102: Non-specific - Mixed function" 31 Nucleoplasm "HPA037924: , HPA037925: " "unprognostic (2.29e-2)" "unprognostic (6.77e-2)" "unprognostic (3.13e-3)" "unprognostic (7.88e-3)" "potential prognostic unfavorable (5.00e-4)" "unprognostic (1.85e-1)" "unprognostic (6.76e-3)" "unprognostic (8.64e-2)" "unprognostic (4.44e-1)" "potential prognostic favorable (7.10e-11)" "unprognostic (1.00e-1)" "potential prognostic favorable (8.28e-4)" "unprognostic (3.61e-1)" "unprognostic (1.36e-1)" "unprognostic (1.03e-1)" "unprognostic (4.00e-1)" "unprognostic (3.24e-2)" "unprognostic (2.18e-1)" "unprognostic (1.13e-2)" "potential prognostic unfavorable (5.91e-4)" "unprognostic (5.39e-2)" "unprognostic (1.27e-1)" "unprognostic (4.82e-2)" "unprognostic (1.06e-2)" "unprognostic (6.78e-3)" "unprognostic (3.79e-2)" "unprognostic (2.45e-1)" "unprognostic (1.26e-1)" "unprognostic (1.62e-1)" STOM "BND7, EPB7, EPB72" ENSG00000148175 Stomatin P27105 9 121338987-121370304 "Plasma proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 458.5;Kupffer cells: 540.1;Neutrophil progenitors: 1252.5;Neutrophils: 456.6;Platelets: 1321.0;Smooth muscle cells: 481.7;Vascular endothelial cells: 572.5" "Cell type enhanced" "Detected in many" "endothelial cell: 560.8;pericyte: 212.8;vascular associated smooth muscle cell: 269.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Colon - Neutrophils, Heart muscle - Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Pituitary gland - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010961, HPA011419" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA 23000000 "Cluster 33: Non-specific - ATP binding" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 162 "Vesicles, Plasma membrane" Cytosol "HPA010961: , HPA011419: " "unprognostic (9.61e-2)" "unprognostic (1.44e-1)" "unprognostic (8.98e-2)" "unprognostic (4.29e-2)" "unprognostic (9.72e-2)" "unprognostic (6.01e-2)" "unprognostic (1.93e-3)" "unprognostic (4.80e-3)" "unprognostic (4.08e-2)" "potential prognostic unfavorable (3.59e-4)" "validated prognostic favorable (5.47e-7)" "validated prognostic favorable (8.29e-5)" "potential prognostic favorable (1.84e-4)" "unprognostic (1.11e-2)" "unprognostic (2.94e-3)" "unprognostic (3.80e-1)" "unprognostic (1.90e-1)" "unprognostic (7.79e-3)" "unprognostic (5.31e-2)" "unprognostic (2.89e-3)" "unprognostic (6.19e-2)" "unprognostic (2.00e-1)" "unprognostic (8.75e-2)" "unprognostic (5.99e-2)" "unprognostic (1.57e-1)" "unprognostic (5.02e-2)" "unprognostic (2.01e-1)" "unprognostic (5.09e-3)" "unprognostic (1.08e-1)" "unprognostic (2.52e-1)" "unprognostic (5.16e-2)" STOML1 "FLJ36370, hUNC-24, SLP-1, STORP" ENSG00000067221 "Stomatin like 1" Q9UBI4 15 73978926-73994622 "Predicted intracellular proteins, Predicted membrane proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 48.7" "Cell type enhanced" "Detected in many" "Breast lactating cells: 23.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014724, HPA042353" Approved Approved Vesicles NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 78: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 98: Neurons - Neurotransmission & signaling" 2 Vesicles "HPA014724: , HPA042353: " "unprognostic (4.58e-2)" "unprognostic (1.60e-2)" "unprognostic (9.14e-2)" "unprognostic (1.67e-2)" "unprognostic (2.32e-1)" "unprognostic (3.78e-1)" "potential prognostic unfavorable (9.70e-5)" "unprognostic (6.64e-2)" "unprognostic (1.27e-1)" "unprognostic (3.05e-1)" "unprognostic (1.73e-2)" "unprognostic (2.47e-1)" "potential prognostic favorable (4.79e-5)" "unprognostic (2.03e-2)" "unprognostic (9.96e-3)" "unprognostic (1.80e-1)" "unprognostic (3.53e-2)" "unprognostic (1.06e-1)" "unprognostic (1.91e-1)" "unprognostic (3.59e-1)" "unprognostic (5.30e-1)" "unprognostic (3.20e-1)" "unprognostic (3.18e-1)" "unprognostic (5.26e-3)" "unprognostic (1.15e-1)" "unprognostic (1.46e-2)" "unprognostic (1.22e-1)" "unprognostic (1.43e-1)" "unprognostic (2.38e-2)" "unprognostic (1.92e-1)" "unprognostic (1.28e-1)" STOML2 "HSPC108, SLP-2" ENSG00000165283 "Stomatin like 2" Q9UJZ1 9 35099776-35103195 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 276.0;Esophageal basal cells: 374.6;Esophageal suprabasal cells: 308.1;Extravillous trophoblasts: 276.6;Gastric progenitor cells: 297.3;Migrating cytotrophoblasts: 301.4;Oocytes: 331.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015944, HPA062016" Supported Supported "Plasma membrane,Cytosol" NA NA 33000 "Cluster 13: Non-specific - Mitochondria" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 97: Non-specific - Cellular respiration" 18 "Plasma membrane, Cytosol" "CAB015944: , HPA062016: " "unprognostic (2.28e-2)" "unprognostic (1.78e-1)" "potential prognostic unfavorable (4.46e-4)" "unprognostic (1.82e-1)" "unprognostic (1.24e-3)" "unprognostic (2.34e-1)" "unprognostic (1.20e-1)" "unprognostic (2.32e-3)" "unprognostic (8.49e-2)" "unprognostic (3.40e-2)" "potential prognostic favorable (2.68e-9)" "unprognostic (5.63e-3)" "unprognostic (1.80e-1)" "validated prognostic unfavorable (2.78e-4)" "validated prognostic unfavorable (5.12e-5)" "unprognostic (2.69e-2)" "unprognostic (1.77e-3)" "unprognostic (9.57e-2)" "unprognostic (2.11e-1)" "unprognostic (3.47e-2)" "unprognostic (9.52e-3)" "unprognostic (2.74e-2)" "unprognostic (4.77e-2)" "unprognostic (8.06e-2)" "unprognostic (8.14e-2)" "unprognostic (2.13e-1)" "unprognostic (6.59e-2)" "unprognostic (1.03e-1)" "unprognostic (1.29e-1)" "unprognostic (8.41e-2)" "unprognostic (3.17e-2)" STOML3 "Epb7.2l, SRO" ENSG00000133115 "Stomatin like 3" Q8TAV4 13 38965925-38990859 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "fallopian tube: 32.8" "Group enriched" "Detected in some" 7 "Endometrial ciliated cells: 100.0;Ependymal cells: 79.8;Epididymal efferent duct ciliated cells: 110.0;Fallopian tube ciliated cells: 196.7;Respiratory ciliated cells: 153.8" "Cell type enriched" "Detected in some" 54 "ependymal cell: 90.3" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 2.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells" "Region enriched" "Detected in many" 6 "olfactory bulb: 23.6" "Low region specificity" "Detected in all" "HPA012892, HPA071011" Enhanced Supported "Plasma membrane" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 107: Ciliated cells - Cilia assembly & function" 4 "Plasma membrane" "HPA012892: , HPA071011: " "unprognostic (9.81e-3)" "unprognostic (1.54e-1)" "unprognostic (2.75e-1)" "unprognostic (1.49e-1)" STON1 "SBLF, stoned-b1" ENSG00000243244 "Stonin 1" Q9Y6Q2 2 48529383-48598513 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 17.1;Bergmann glia: 313.6;Choroid plexus epithelial cells: 91.7;Ependymal cells: 64.0;Oligodendrocyte progenitor cells: 24.9" "Cell type enriched" "Detected in all" 4 "Bergmann glia: 386.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 15 "basophil: 1.9;neutrophil: 1.0" "Lineage enriched" "Detected in single" 19 "granulocytes: 1.9" "Cancer enhanced" "Detected in many" "testis cancer: 18.0" "Adrenal gland - Fibroblasts, Liver - Hepatic stellate cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005715 Uncertain NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 44: Non-specific - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 28: Astrocytes - Homeostasis & neuron support" 1 "HPA005715: " "unprognostic (6.42e-2)" "unprognostic (7.96e-2)" "unprognostic (7.54e-2)" "unprognostic (3.61e-1)" "unprognostic (7.12e-2)" "unprognostic (8.65e-2)" "unprognostic (3.53e-2)" "unprognostic (8.04e-2)" "unprognostic (1.30e-1)" "unprognostic (1.75e-2)" "validated prognostic favorable (4.13e-10)" "validated prognostic favorable (2.79e-4)" "unprognostic (8.63e-2)" "unprognostic (2.36e-1)" "unprognostic (1.63e-1)" "unprognostic (2.19e-1)" "unprognostic (5.88e-2)" "unprognostic (9.39e-2)" "unprognostic (8.05e-2)" "unprognostic (1.85e-1)" "unprognostic (2.18e-1)" "unprognostic (1.83e-1)" "unprognostic (1.02e-1)" "unprognostic (3.15e-2)" "unprognostic (4.49e-2)" "unprognostic (3.72e-2)" "unprognostic (7.79e-3)" "unprognostic (1.43e-1)" "unprognostic (7.38e-3)" "unprognostic (1.27e-2)" STON1-GTF2A1L SALF ENSG00000068781 "STON1-GTF2A1L readthrough" 2 48529925-48776517 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Adipocytes: 24.9;Basal prostatic cells: 13.8;Endometrial stromal cells: 14.6;Late primary spermatocytes: 20.1;Müller glia: 19.7;Pericytes: 14.0;Podocytes: 65.3;Schwann cells: 17.0;Smooth muscle cells: 32.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 18 "testis cancer: 6.7" "HPA005715, HPA074358" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 43: Hindbrain - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 57: Podocytes - Glomerular filtration" Nucleoplasm Cytosol "HPA005715: , HPA074358: " "unprognostic (1.25e-1)" "unprognostic (1.18e-2)" "unprognostic (6.06e-2)" "unprognostic (1.22e-1)" "unprognostic (4.98e-2)" STON2 "STN2, STNB2" ENSG00000140022 "Stonin 2" Q8WXE9 14 81260652-81436465 "Plasma proteins, Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.4" "Cell type enhanced" "Detected in many" "Astrocytes: 415.5;Endometrial ciliated cells: 291.7;Ependymal cells: 378.4;Lymphatic endothelial cells: 306.1;Platelets: 1148.6" "Cell type enhanced" "Detected in many" "astrocyte: 429.3;ependymal cell: 390.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Urothelial cells, Spleen - Endothelial cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003086 Enhanced Approved Nucleoli,Cytosol NA NA 4500 "Cluster 40: Monocytes - Innate immune response" "Cluster 78: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 47: Leukemia - Hemostasis" "Cluster 47: Platelets - Hemostasis" 15 "Nucleoli, Cytosol" "HPA003086: " "unprognostic (1.88e-1)" "unprognostic (2.16e-1)" "unprognostic (2.62e-1)" "unprognostic (3.86e-2)" "unprognostic (1.15e-1)" "unprognostic (1.27e-1)" "unprognostic (9.09e-2)" "unprognostic (8.99e-2)" "unprognostic (7.05e-2)" "unprognostic (3.95e-1)" "unprognostic (1.23e-3)" "unprognostic (2.58e-2)" "unprognostic (1.06e-3)" "unprognostic (1.43e-2)" "unprognostic (4.14e-2)" "unprognostic (1.67e-2)" "unprognostic (2.08e-3)" "unprognostic (3.05e-3)" "unprognostic (7.00e-3)" "unprognostic (3.04e-1)" "unprognostic (1.51e-1)" "unprognostic (6.83e-2)" "unprognostic (1.02e-1)" "unprognostic (9.57e-2)" "unprognostic (3.65e-2)" "unprognostic (6.24e-2)" "unprognostic (5.29e-3)" "unprognostic (2.24e-2)" "unprognostic (5.16e-2)" "unprognostic (2.82e-2)" STOX1 "C10orf24, FLJ25162" ENSG00000165730 "Storkhead box 1" Q6ZVD7 10 68827531-68895432 "Disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.7;choroid plexus: 26.1" "Cell type enhanced" "Detected in many" "Astrocytes: 155.1;Choroid plexus epithelial cells: 307.6;Endometrial ciliated cells: 115.3;Ependymal cells: 93.1;Epididymal efferent duct ciliated cells: 114.2;Fallopian tube ciliated cells: 137.6;Medullary thymic epithelial cells: 81.6;Pituitary stem cells: 155.0;Respiratory ciliated cells: 186.7;Retinal pigment epithelial cells: 68.2" "Group enriched" "Detected in all" 5 "astrocyte: 132.4;choroid plexus epithelial cell: 300.5;ependymal cell: 102.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Lung - Respiratory ciliated cells, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA037844, HPA037845" Uncertain Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" No NA "Cluster 24: Non-specific - Transcription" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 52: Non-specific - Mitochondria" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 3 Nucleoplasm "Nucleoli fibrillar center, Cytosol" "HPA037844: , HPA037845: " "unprognostic (1.94e-2)" "potential prognostic favorable (4.37e-4)" "unprognostic (2.53e-1)" "unprognostic (6.72e-2)" "unprognostic (2.29e-1)" "unprognostic (5.39e-3)" "unprognostic (4.82e-3)" "unprognostic (1.04e-2)" "unprognostic (4.80e-2)" "unprognostic (1.61e-1)" "unprognostic (5.68e-2)" "potential prognostic unfavorable (1.08e-5)" "unprognostic (1.15e-2)" "unprognostic (2.69e-1)" "unprognostic (1.20e-3)" "potential prognostic favorable (6.43e-6)" "unprognostic (2.00e-2)" "unprognostic (1.12e-1)" "unprognostic (4.20e-2)" "unprognostic (6.58e-3)" "unprognostic (1.69e-1)" "unprognostic (7.25e-2)" "unprognostic (2.00e-1)" "unprognostic (5.77e-2)" "unprognostic (1.72e-1)" STOX2 DKFZp762K222 ENSG00000173320 "Storkhead box 2" Q9P2F5 4 183797692-184023526 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 759.3;Corticotrophs: 882.6;Gonadotrophs: 579.8;Lacrimal acinar cells: 721.9;Lactotrophs: 724.7;Lymphatic endothelial cells: 839.2;Salivary acinar cells: 613.1;Somatotrophs: 873.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 13.1" "Adipose subcutaneous - Smooth muscle cells, Colon - Enteric glia cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049776, HPA065002" Uncertain Approved "Nucleoplasm,Actin filaments,Cytosol" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 34: Non-specific - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 5 "Nucleoplasm, Cytosol" "Actin filaments" "HPA049776: , HPA065002: " "unprognostic (1.32e-1)" "unprognostic (8.68e-2)" "unprognostic (6.40e-2)" "unprognostic (2.20e-1)" "unprognostic (5.62e-2)" "unprognostic (2.67e-1)" "unprognostic (4.17e-2)" "unprognostic (1.09e-1)" "validated prognostic favorable (5.64e-4)" "validated prognostic favorable (1.54e-4)" "unprognostic (8.87e-2)" "unprognostic (1.07e-1)" "unprognostic (3.40e-3)" "unprognostic (4.72e-2)" "unprognostic (1.94e-2)" "unprognostic (2.00e-1)" "unprognostic (5.10e-1)" "unprognostic (9.52e-2)" "unprognostic (3.43e-2)" "unprognostic (2.92e-1)" "unprognostic (1.87e-2)" "unprognostic (3.10e-2)" "unprognostic (8.85e-2)" "potential prognostic unfavorable (3.09e-4)" "unprognostic (2.83e-2)" STPG1 "C1orf201, FLJ33340, MAPO2" ENSG00000001460 "Sperm tail PG-rich repeat containing 1" Q5TH74 1 24356999-24416934 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 26.1" "Group enriched" "Detected in many" 4 "Early spermatids: 294.6;Late spermatids: 1128.3" "Cell type enhanced" "Detected in all" "ependymal cell: 101.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA024301 Approved Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 37: Non-specific - mRNA processing" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" Nucleoplasm "HPA024301: " "unprognostic (3.67e-2)" "unprognostic (3.04e-1)" "unprognostic (8.61e-2)" "unprognostic (2.52e-2)" "unprognostic (2.41e-1)" "potential prognostic unfavorable (6.56e-5)" "unprognostic (2.50e-3)" "unprognostic (1.38e-2)" "unprognostic (4.82e-2)" "potential prognostic favorable (2.67e-8)" "unprognostic (4.64e-2)" "unprognostic (8.32e-3)" "unprognostic (6.21e-3)" "unprognostic (4.27e-3)" "unprognostic (1.31e-1)" "unprognostic (1.24e-2)" "unprognostic (1.88e-1)" "unprognostic (2.19e-1)" "unprognostic (1.99e-1)" "unprognostic (3.13e-1)" "unprognostic (1.92e-1)" "unprognostic (4.98e-2)" "unprognostic (2.71e-2)" "unprognostic (1.36e-1)" "unprognostic (2.00e-1)" "unprognostic (6.97e-2)" "unprognostic (1.44e-1)" "unprognostic (4.97e-1)" "unprognostic (5.33e-2)" STPG2 "C4orf37, MGC46496" ENSG00000163116 "Sperm tail PG-rich repeat containing 2" Q8N412 4 97184093-98143476 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "testis: 1.8" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 269.1;Distal convoluted tubule cells: 383.6;Loop of henle epithelial cells: 422.3;Podocytes: 240.5;Proximal tubule cells: 570.6;Renal collecting duct intercalated cells: 545.7;Renal connecting tubule cells: 278.4;Thyrotrophs: 270.7" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA059473 Approved "Principal piece" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" "Principal piece" "HPA059473: " "unprognostic (5.84e-2)" STPG3 "C9orf173, FLJ40246" ENSG00000197768 "Sperm-tail PG-rich repeat containing 3" Q8N7X2 9 137251261-137253483 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "testis: 41.0" "Cell type enriched" "Detected in some" 6 "Late spermatids: 2287.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Liver - Hepatocytes, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA044352 Uncertain Vesicles NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 6: Non-specific - Immune response" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" Vesicles "HPA044352: " "unprognostic (3.90e-1)" "potential prognostic favorable (7.26e-4)" "unprognostic (1.11e-1)" STPG4 "C2orf61, FLJ40172" ENSG00000239605 "Sperm-tail PG-rich repeat containing 4" Q8N801 2 47045538-47155308 "Predicted intracellular proteins" "Chromatin regulator, Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 65 "testis: 13.7" "Cell type enhanced" "Detected in many" "Adipocytes: 17.8;Early spermatids: 64.1;Epicardial cells: 40.9;Fibro-adipogenic progenitors: 23.2;Late primary spermatocytes: 49.5;Late spermatids: 47.1;Oocytes: 27.6" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 17.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 1.8" "Skin - Eccrine sweat gland cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA047366, HPA052691" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 38: Sub-cortical - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" Nucleoplasm Cytosol "HPA047366: , HPA052691: " "unprognostic (8.05e-2)" "unprognostic (2.58e-1)" STRA6 FLJ12541 ENSG00000137868 "Signaling receptor and transporter of retinol STRA6" Q9BX79 15 74179466-74212267 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport Receptor "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 22.3" "Group enriched" "Detected in some" 5 "Papillary tip epithelial cells: 29.2;Proximal tubule cells: 21.1" "Group enriched" "Detected in some" 7 "endothelial cell: 8.7;fibroblast: 15.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 30.0" "Adrenal gland - Adrenal medulla cells, Kidney - Proximal tubular cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040839 Approved NA NA "Cluster 75: Ovary - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 88: Proximal tubular cells - Transmembrane transport" "HPA040839: " "unprognostic (3.16e-1)" "unprognostic (2.67e-2)" "potential prognostic favorable (4.31e-4)" "unprognostic (5.76e-3)" "unprognostic (1.12e-1)" "unprognostic (9.98e-2)" "unprognostic (9.05e-2)" "unprognostic (2.86e-2)" "unprognostic (7.25e-2)" "unprognostic (2.29e-1)" "unprognostic (2.33e-1)" "unprognostic (8.78e-3)" "unprognostic (9.89e-3)" "unprognostic (1.92e-1)" "unprognostic (1.31e-1)" "unprognostic (4.60e-1)" "unprognostic (5.45e-2)" "unprognostic (1.17e-1)" "unprognostic (1.66e-1)" "unprognostic (3.67e-2)" "unprognostic (7.16e-3)" "unprognostic (1.67e-1)" "unprognostic (3.57e-2)" "unprognostic (3.49e-1)" "unprognostic (1.96e-2)" "unprognostic (7.50e-3)" STRA8 ENSG00000146857 "Stimulated by retinoic acid 8" Q7Z7C7 7 135231979-135258663 "Predicted intracellular proteins" "Differentiation, DNA replication, Meiosis, Oogenesis, Spermatogenesis, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "testis: 1.3" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 4.5;Cytotrophoblasts: 5.9;Differentiating spermatogonia: 20.9;Early primary spermatocytes: 11.0;Epicardial cells: 13.6;Oocytes: 13.8;Proximal tubule cells: 3.2;Syncytiotrophoblasts: 3.8" "Cell type enriched" "Detected in single" 27 "choroid plexus epithelial cell: 20.2" "Cancer enhanced" "Detected in single" "Kidney Renal Clear Cell Carcinoma (TCGA): 2.6" "Region enriched" "Detected in many" 8 "choroid plexus: 20.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Macrophages, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Not detected" "Not detected" HPA078044 Approved Cytosol NA NA "Cluster 47: Testis - Mixed function" "Cluster 36: Choroid plexus - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 7 Cytosol "HPA078044: " "unprognostic (3.21e-1)" "unprognostic (4.12e-2)" "unprognostic (1.23e-1)" STRADA "LYK5, NY-BR-96, Stlk, STRAD" ENSG00000266173 "STE20 related adaptor alpha" Q7RTN6 17 63682336-63741986 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 76.0;Bergmann glia: 82.0;Brain excitatory neurons: 59.6;Brain inhibitory neurons: 55.8;Cardiomyocytes: 74.7;Choroid plexus epithelial cells: 73.1;Ependymal cells: 79.2;Epicardial cells: 84.1;Microglia: 86.7;Oligodendrocyte progenitor cells: 51.8;Oligodendrocytes: 97.2;Other brain neurons: 50.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031637 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 64: Non-specific - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 11 "Nucleoplasm, Cytosol" "HPA031637: " "unprognostic (4.08e-2)" "unprognostic (7.43e-2)" "unprognostic (7.77e-2)" "unprognostic (1.57e-1)" "unprognostic (7.30e-3)" "unprognostic (2.09e-2)" "unprognostic (2.26e-1)" "unprognostic (3.38e-2)" "unprognostic (1.06e-1)" "unprognostic (7.72e-3)" "potential prognostic unfavorable (3.03e-5)" "unprognostic (1.51e-2)" "unprognostic (1.62e-2)" "potential prognostic unfavorable (4.26e-4)" "unprognostic (8.61e-2)" "unprognostic (3.03e-1)" "unprognostic (3.06e-2)" "unprognostic (3.33e-1)" "unprognostic (1.86e-2)" "unprognostic (3.10e-1)" "unprognostic (3.04e-3)" "unprognostic (1.20e-3)" "unprognostic (1.18e-3)" "unprognostic (1.47e-2)" "unprognostic (4.23e-3)" "unprognostic (7.11e-2)" "unprognostic (1.75e-2)" "unprognostic (2.06e-1)" "unprognostic (3.83e-2)" "unprognostic (1.50e-1)" "unprognostic (4.14e-1)" STRADB "ALS2CR2, CALS-21, ILPIP, ILPIPA, PAPK" ENSG00000082146 "STE20 related adaptor beta" Q9C0K7 2 201387858-201480846 "Enzymes, Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 8 "Cardiomyocytes: 1662.8" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 204.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026549, HPA028520" Approved Supported "Nucleoplasm,Primary cilium,Primary cilium tip,Cytosol" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 13 "Nucleoplasm, Cytosol" "Primary cilium, Primary cilium tip" "HPA026549: , HPA028520: " "unprognostic (9.75e-2)" "unprognostic (1.12e-1)" "unprognostic (1.04e-1)" "unprognostic (1.10e-2)" "unprognostic (1.02e-1)" "unprognostic (2.45e-2)" "unprognostic (9.70e-2)" "unprognostic (3.18e-1)" "unprognostic (1.45e-1)" "unprognostic (4.01e-2)" "unprognostic (3.02e-2)" "unprognostic (4.31e-1)" "unprognostic (1.23e-1)" "unprognostic (1.49e-2)" "unprognostic (4.55e-2)" "unprognostic (3.97e-2)" "unprognostic (1.78e-1)" "unprognostic (2.15e-1)" "unprognostic (8.55e-2)" "unprognostic (6.28e-3)" "unprognostic (1.39e-1)" "unprognostic (1.41e-1)" "unprognostic (6.99e-3)" "unprognostic (1.42e-1)" "unprognostic (7.86e-2)" "potential prognostic unfavorable (4.31e-4)" "potential prognostic unfavorable (8.07e-4)" "unprognostic (2.29e-1)" "unprognostic (2.23e-1)" "potential prognostic favorable (4.37e-4)" "unprognostic (2.08e-1)" STRAP "MAWD, pt-wd, UNRIP" ENSG00000023734 "Serine/threonine kinase receptor associated protein" Q9Y3F4 12 15882387-15903478 "Cancer-related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 396.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027320, HPA055557, HPA073876" Approved Supported "Cell Junctions,Cytosol" NA NA 330000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 38: Non-specific - Transcription" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 73 Cytosol "Cell Junctions" "HPA027320: , HPA055557: , HPA073876: " "potential prognostic unfavorable (8.32e-4)" "unprognostic (1.26e-3)" "unprognostic (2.11e-2)" "unprognostic (7.29e-3)" "unprognostic (5.31e-2)" "unprognostic (8.38e-2)" "unprognostic (1.31e-1)" "unprognostic (2.64e-1)" "unprognostic (4.65e-3)" "unprognostic (2.05e-2)" "potential prognostic favorable (5.89e-6)" "unprognostic (3.38e-1)" "unprognostic (3.48e-1)" "validated prognostic unfavorable (3.55e-5)" "validated prognostic unfavorable (1.41e-5)" "potential prognostic unfavorable (5.72e-6)" "unprognostic (9.67e-3)" "unprognostic (7.08e-2)" "unprognostic (2.51e-1)" "potential prognostic unfavorable (1.07e-4)" "unprognostic (2.42e-1)" "unprognostic (1.89e-1)" "potential prognostic unfavorable (1.59e-4)" "unprognostic (9.16e-2)" "unprognostic (3.06e-3)" "unprognostic (6.22e-2)" "unprognostic (2.82e-1)" "unprognostic (2.79e-1)" "unprognostic (3.24e-1)" "unprognostic (2.72e-3)" "unprognostic (4.10e-1)" STRBP "FLJ11307, ILF3L, SPNR" ENSG00000165209 "Spermatid perinuclear RNA binding protein" Q96SI9 9 123109500-123268586 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein, DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ependymal cells: 648.3;Pituitary stem cells: 706.4;Respiratory ciliated cells: 516.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Spleen - B-cells (Spleen), Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020651 Approved NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 40 "HPA020651: " "unprognostic (3.01e-2)" "potential prognostic unfavorable (2.10e-4)" "unprognostic (1.53e-1)" "unprognostic (1.44e-1)" "unprognostic (7.37e-2)" "unprognostic (2.62e-1)" "unprognostic (2.80e-1)" "unprognostic (3.57e-3)" "unprognostic (1.93e-1)" "unprognostic (1.91e-2)" "potential prognostic favorable (5.10e-6)" "unprognostic (2.99e-3)" "unprognostic (1.00e-1)" "unprognostic (3.48e-3)" "unprognostic (1.34e-3)" "unprognostic (2.02e-1)" "unprognostic (1.41e-1)" "unprognostic (2.01e-1)" "unprognostic (1.12e-2)" "unprognostic (8.76e-2)" "unprognostic (5.32e-3)" "unprognostic (1.95e-1)" "unprognostic (1.64e-2)" "unprognostic (3.45e-1)" "unprognostic (5.59e-3)" "unprognostic (2.08e-1)" "unprognostic (1.50e-2)" "unprognostic (1.96e-2)" "unprognostic (4.36e-1)" "unprognostic (2.55e-1)" "unprognostic (4.71e-2)" STRC DFNB16 ENSG00000242866 Stereocilin Q7RTU9 15 43599563-43618800 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" Hearing "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 9 "brain: 40.6" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 7.2;Brain inhibitory neurons: 3.1;Cone photoreceptor cells: 4.1;Corticotrophs: 4.8;Early primary spermatocytes: 2.9;Epicardial cells: 4.5;Mesothelial cells: 3.3;Retinal ganglion cells: 11.6;Rod photoreceptor cells: 3.7" "Cell type enhanced" "Detected in many" "upper rhombic lip: 15.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pituitary gland - Corticotropes" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA048083 Enhanced NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 37: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 2: Cerebellar granular cells - Neuronal signaling" "HPA048083: " "unprognostic (2.65e-3)" STRIP1 "FAM40A, FAR11A, FLJ14743, KIAA1761" ENSG00000143093 "Striatin interacting protein 1" Q5VSL9 1 110031577-110074641 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 66.9;Late spermatids: 83.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060302, HPA060498" Approved Supported Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 64: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 37: Non-specific - mRNA processing" "Cluster 7: Non-specific - Transcription" 56 Cytosol "HPA060302: , HPA060498: " "unprognostic (9.53e-3)" "unprognostic (1.86e-1)" "unprognostic (1.15e-1)" "unprognostic (5.08e-3)" "unprognostic (1.42e-2)" "unprognostic (4.64e-1)" "potential prognostic favorable (2.46e-6)" "unprognostic (6.32e-2)" "unprognostic (1.58e-3)" "unprognostic (4.52e-3)" "potential prognostic favorable (4.07e-4)" "unprognostic (1.59e-1)" "potential prognostic unfavorable (6.95e-4)" "unprognostic (1.46e-1)" "unprognostic (2.11e-3)" "unprognostic (2.16e-1)" "unprognostic (4.17e-2)" "unprognostic (1.97e-1)" "unprognostic (3.38e-1)" "unprognostic (5.28e-2)" "unprognostic (1.63e-1)" "unprognostic (2.73e-1)" "unprognostic (9.43e-3)" "unprognostic (2.45e-3)" "unprognostic (3.44e-1)" "unprognostic (4.62e-2)" "unprognostic (2.78e-1)" "unprognostic (3.13e-1)" "unprognostic (2.45e-1)" STRIP2 "FAM40B, FAR11B, KIAA1170" ENSG00000128578 "Striatin interacting protein 2" Q9ULQ0 7 129434432-129488399 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.6;choroid plexus: 43.8;skeletal muscle: 26.7" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 207.8;Choroid plexus epithelial cells: 596.9;Early primary spermatocytes: 213.7;Müller glia: 164.8;Myonuclei: 112.8;Retinal pigment epithelial cells: 989.0" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 644.9;medium spiny neuron: 495.2" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in all" 5 "basal ganglia: 91.7;choroid plexus: 178.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Kidney - Proximal tubular cells, Pituitary gland - Lactotropes" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "basal ganglia: 129.5" HPA019657 Approved Approved Cytosol NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" 22 Cytosol "HPA019657: " "unprognostic (2.83e-1)" "unprognostic (5.97e-2)" "unprognostic (1.38e-2)" "unprognostic (4.37e-1)" "unprognostic (1.30e-1)" "unprognostic (2.87e-1)" "unprognostic (4.71e-2)" "unprognostic (3.04e-2)" "unprognostic (3.87e-3)" "potential prognostic unfavorable (7.02e-4)" "unprognostic (1.60e-1)" "unprognostic (1.57e-1)" "potential prognostic unfavorable (2.74e-6)" "unprognostic (6.54e-2)" "unprognostic (2.79e-1)" "unprognostic (1.63e-1)" "unprognostic (9.50e-2)" "unprognostic (1.71e-3)" "unprognostic (1.56e-1)" "unprognostic (2.20e-1)" "unprognostic (1.60e-1)" "potential prognostic favorable (6.04e-4)" "unprognostic (2.49e-2)" "unprognostic (1.69e-2)" STRIT1 DWORF ENSG00000240045 "Small transmembrane regulator of ion transport 1" P0DN84 3 155290227-155293683 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 35 "skeletal muscle: 1862.6;tongue: 652.3" "Group enriched" "Detected in some" 9 "Myonuclei: 104.1;Thymic myoid cells: 318.2" "Group enriched" "Detected in some" 5 "medium spiny neuron: 3.2;thalamic excitatory: 2.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Kidney cancer: 1.0" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in single" NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 32 "unprognostic (4.39e-2)" "unprognostic (4.13e-2)" "unprognostic (6.34e-2)" "unprognostic (6.32e-2)" "unprognostic (1.26e-1)" "unprognostic (1.26e-1)" "unprognostic (3.16e-1)" STRN "PPP2R6A, STRN1" ENSG00000115808 Striatin O43815 2 36837698-36966536 "Cancer-related genes, Predicted intracellular proteins" Calmodulin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 434.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017286 Approved Approved Nucleoplasm,Cytosol No No "Cluster 11: Esophagus - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 85 Cytosol Nucleoplasm "HPA017286: " "unprognostic (4.67e-1)" "unprognostic (6.72e-2)" "unprognostic (2.37e-1)" "unprognostic (1.20e-2)" "unprognostic (5.81e-2)" "unprognostic (1.57e-1)" "unprognostic (4.71e-2)" "unprognostic (2.61e-1)" "unprognostic (1.25e-1)" "unprognostic (4.11e-2)" "potential prognostic favorable (7.55e-7)" "unprognostic (1.59e-2)" "unprognostic (1.43e-2)" "unprognostic (9.18e-3)" "unprognostic (7.03e-3)" "unprognostic (2.68e-2)" "unprognostic (5.52e-3)" "unprognostic (2.19e-1)" "unprognostic (2.56e-1)" "unprognostic (1.44e-2)" "unprognostic (5.66e-2)" "potential prognostic unfavorable (2.50e-4)" "unprognostic (7.75e-3)" "unprognostic (2.12e-1)" "unprognostic (2.96e-3)" "unprognostic (1.82e-1)" "unprognostic (1.45e-1)" "unprognostic (2.27e-1)" "unprognostic (1.31e-1)" "unprognostic (4.78e-2)" "unprognostic (3.04e-2)" STRN3 "PPP2R6B, S/G2NA, SG2NA" ENSG00000196792 "Striatin 3" Q13033 14 30893799-31026401 "Plasma proteins, Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003392, HPA004636, CAB069925" Approved Approved "Plasma membrane,Actin filaments,Primary cilium,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 103: Non-specific - Basic cellular processes" 83 "Plasma membrane, Cytosol" "Actin filaments, Primary cilium" "CAB069925: , HPA003392: , HPA004636: " "unprognostic (1.55e-1)" "unprognostic (9.38e-2)" "unprognostic (1.24e-1)" "unprognostic (9.62e-2)" "unprognostic (2.18e-2)" "unprognostic (4.60e-2)" "unprognostic (3.94e-2)" "unprognostic (3.76e-3)" "unprognostic (3.84e-2)" "unprognostic (1.30e-2)" "potential prognostic favorable (8.06e-6)" "unprognostic (4.03e-3)" "unprognostic (8.28e-2)" "unprognostic (6.37e-2)" "unprognostic (7.86e-2)" "unprognostic (1.04e-2)" "unprognostic (6.28e-3)" "unprognostic (1.17e-1)" "unprognostic (3.75e-1)" "unprognostic (2.85e-2)" "unprognostic (1.42e-3)" "unprognostic (3.02e-2)" "unprognostic (3.44e-2)" "unprognostic (1.32e-1)" "unprognostic (3.47e-1)" "unprognostic (2.20e-1)" "unprognostic (2.67e-1)" "unprognostic (1.39e-2)" "unprognostic (8.07e-2)" "unprognostic (4.49e-2)" "unprognostic (4.42e-2)" STRN4 "PPP2R6C, ZIN" ENSG00000090372 "Striatin 4" Q9NRL3 19 46719511-46746994 "Predicted intracellular proteins, Predicted membrane proteins" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Megakaryocytes: 154.5;Platelets: 176.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043051, HPA043527, HPA056706" Supported Approved Cytosol NA NA 14000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 67: Testis - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 47: Platelets - Hemostasis" 59 Cytosol "HPA043051: , HPA043527: , HPA056706: " "unprognostic (2.29e-1)" "unprognostic (2.06e-1)" "unprognostic (2.09e-1)" "unprognostic (1.15e-3)" "unprognostic (1.12e-1)" "unprognostic (3.87e-2)" "unprognostic (2.63e-1)" "unprognostic (2.06e-1)" "unprognostic (6.84e-2)" "unprognostic (6.37e-2)" "unprognostic (5.50e-3)" "unprognostic (1.05e-1)" "unprognostic (3.63e-2)" "potential prognostic unfavorable (8.30e-5)" "unprognostic (3.18e-2)" "unprognostic (1.01e-2)" "unprognostic (2.35e-2)" "unprognostic (3.37e-2)" "unprognostic (1.16e-1)" "unprognostic (1.36e-3)" "unprognostic (4.99e-1)" "unprognostic (9.35e-2)" "unprognostic (2.72e-1)" "unprognostic (1.51e-2)" "unprognostic (2.41e-1)" "unprognostic (3.61e-3)" "unprognostic (3.04e-2)" "unprognostic (4.36e-1)" "unprognostic (4.34e-2)" "unprognostic (2.12e-1)" "unprognostic (2.67e-1)" STS "ARSC, ARSC1" ENSG00000101846 "Steroid sulfatase" X 7147237-7804358 "Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 24.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 139.8;Foveolar cells: 244.3;Syncytiotrophoblasts: 207.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Myeloma: 35.2" "Low region specificity" "Detected in all" HPA002904 Enhanced NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 68: Foveolar cells - Mucosal defense" "HPA002904: " "unprognostic (1.20e-1)" "unprognostic (2.46e-1)" "unprognostic (3.15e-1)" "unprognostic (2.96e-1)" "unprognostic (4.10e-2)" "unprognostic (1.27e-2)" "unprognostic (3.15e-1)" "unprognostic (2.51e-3)" "unprognostic (1.25e-1)" "unprognostic (1.05e-1)" "potential prognostic favorable (3.18e-6)" "unprognostic (6.37e-3)" "unprognostic (5.63e-2)" "unprognostic (1.59e-2)" "unprognostic (3.86e-2)" "unprognostic (2.58e-1)" "unprognostic (5.32e-2)" "unprognostic (1.77e-2)" "unprognostic (3.23e-2)" "unprognostic (3.10e-1)" "unprognostic (1.86e-1)" "unprognostic (1.06e-3)" "unprognostic (6.83e-2)" "unprognostic (5.45e-2)" "unprognostic (9.15e-3)" "unprognostic (6.32e-2)" "unprognostic (2.61e-1)" "unprognostic (3.94e-1)" "unprognostic (2.63e-1)" "unprognostic (3.65e-1)" "unprognostic (4.20e-1)" STT3A "ITM1, MGC9042, STT3-A, TMC" ENSG00000134910 "STT3 oligosaccharyltransferase complex catalytic subunit A" P46977 11 125591712-125625215 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Glycosyltransferase, Transferase" "Cancer-related genes, Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 368.8" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030735 Approved NA NA 19000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 8: Non-specific - Secretory pathway" 40 "HPA030735: " "unprognostic (1.09e-1)" "unprognostic (3.39e-3)" "unprognostic (1.32e-1)" "unprognostic (3.41e-2)" "unprognostic (6.70e-3)" "unprognostic (1.44e-1)" "unprognostic (2.25e-1)" "unprognostic (4.34e-2)" "unprognostic (8.54e-2)" "unprognostic (3.20e-3)" "potential prognostic favorable (6.45e-5)" "unprognostic (4.97e-2)" "unprognostic (3.17e-2)" "unprognostic (1.44e-3)" "unprognostic (2.35e-2)" "unprognostic (1.15e-2)" "potential prognostic unfavorable (9.60e-4)" "unprognostic (7.04e-2)" "unprognostic (1.40e-1)" "unprognostic (2.32e-1)" "unprognostic (2.61e-2)" "unprognostic (3.41e-3)" "unprognostic (1.07e-1)" "unprognostic (2.72e-1)" "unprognostic (9.65e-2)" "unprognostic (3.90e-2)" "unprognostic (8.46e-2)" "unprognostic (5.94e-2)" "unprognostic (7.07e-2)" "unprognostic (1.36e-1)" "unprognostic (1.29e-1)" STT3B "FLJ90106, SIMP, STT3-B" ENSG00000163527 "STT3 oligosaccharyltransferase complex catalytic subunit B" Q8TCJ2 3 31532638-31637616 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 429.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036448, HPA036646" Approved Supported "Endoplasmic reticulum" NA NA 7100 "Cluster 30: Non-specific - DNA binding" "Cluster 61: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 105 "Endoplasmic reticulum" "HPA036448: , HPA036646: " "unprognostic (2.69e-1)" "unprognostic (5.15e-2)" "unprognostic (1.79e-2)" "unprognostic (4.48e-3)" "unprognostic (5.02e-2)" "unprognostic (1.24e-1)" "unprognostic (2.50e-1)" "unprognostic (1.08e-2)" "unprognostic (9.25e-3)" "unprognostic (1.27e-2)" "potential prognostic favorable (5.45e-5)" "unprognostic (1.22e-1)" "unprognostic (7.06e-2)" "unprognostic (3.08e-2)" "unprognostic (1.10e-1)" "unprognostic (2.86e-2)" "unprognostic (1.36e-1)" "unprognostic (5.52e-2)" "unprognostic (2.23e-1)" "unprognostic (1.35e-1)" "unprognostic (4.31e-3)" "unprognostic (3.46e-3)" "unprognostic (3.33e-1)" "unprognostic (1.32e-1)" "unprognostic (1.79e-3)" "unprognostic (5.98e-2)" "unprognostic (2.96e-3)" "unprognostic (1.64e-1)" "unprognostic (1.85e-1)" "unprognostic (5.00e-2)" "unprognostic (1.17e-1)" STUB1 "CHIP, HSPABP2, NY-CO-7, SDCCAG7, UBOX1" ENSG00000103266 "STIP1 homology and U-box containing protein 1" Q9UNE7 16 680224-682870 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 478.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037202, CAB037209, HPA041222, HPA043531" Enhanced Supported Nucleoplasm,Cytosol NA NA 8700 "Cluster 45: Eosinophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 1: Neurons - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 295 "Nucleoplasm, Cytosol" "CAB037202: , CAB037209: , HPA041222: , HPA043531: " "unprognostic (5.87e-2)" "unprognostic (1.36e-1)" "unprognostic (2.28e-3)" "unprognostic (1.64e-2)" "unprognostic (3.89e-1)" "unprognostic (1.54e-1)" "unprognostic (6.71e-3)" "unprognostic (1.77e-1)" "unprognostic (8.85e-2)" "unprognostic (3.59e-2)" "potential prognostic favorable (8.59e-8)" "unprognostic (1.05e-1)" "potential prognostic favorable (5.41e-4)" "unprognostic (5.06e-3)" "unprognostic (3.00e-3)" "unprognostic (7.06e-2)" "unprognostic (1.27e-2)" "unprognostic (1.20e-1)" "unprognostic (1.69e-1)" "unprognostic (2.98e-1)" "unprognostic (8.66e-2)" "unprognostic (3.60e-1)" "unprognostic (1.42e-1)" "unprognostic (1.10e-1)" "unprognostic (2.72e-1)" "unprognostic (3.46e-1)" "unprognostic (4.20e-1)" "unprognostic (3.01e-1)" "unprognostic (1.33e-1)" "unprognostic (8.47e-2)" "unprognostic (2.45e-1)" STUM "C1orf95, DKFZp761P211" ENSG00000203685 "Stum, mechanosensory transduction mediator homolog" Q69YW2 1 226548764-226609230 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 47.5;intestine: 15.2" "Cell type enhanced" "Detected in many" "Astrocytes: 66.5;Brain excitatory neurons: 34.7;Distal convoluted tubule cells: 45.0;Lactotrophs: 93.4;Loop of henle epithelial cells: 30.9;Megakaryocytes: 37.1;Myosatellite cells: 91.8;Renal collecting duct intercalated cells: 88.1;Thyrotrophs: 103.8;Vascular smooth muscle cells: 33.1" "Cell type enhanced" "Detected in many" "hippocampal CA4: 151.8" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 13.0" "Region enhanced" "Detected in all" "medulla oblongata: 551.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 2.4;lung cancer: 1.8" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Smooth muscle cells, Liver - Hepatic stellate cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074381 Approved Cytosol NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 35: Neurons - Synaptic function & neurogenesis" 1 Cytosol "HPA074381: " "unprognostic (9.13e-3)" "unprognostic (1.97e-2)" "unprognostic (7.15e-2)" "potential prognostic favorable (7.74e-4)" "unprognostic (2.26e-2)" "potential prognostic favorable (2.93e-4)" "unprognostic (1.68e-1)" "unprognostic (5.75e-2)" "unprognostic (1.58e-3)" "unprognostic (5.32e-3)" "unprognostic (2.63e-1)" "unprognostic (1.15e-2)" "unprognostic (1.87e-2)" "unprognostic (4.39e-1)" "unprognostic (1.64e-2)" "unprognostic (1.22e-2)" STX10 "hsyn10, SYN10" ENSG00000104915 "Syntaxin 10" O60499 19 13144058-13150383 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 171.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "HPA035303, HPA056439" Approved Supported "Golgi apparatus,Vesicles" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 64: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 23: Non-specific - Transcription" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 53 "Golgi apparatus, Vesicles" "HPA035303: , HPA056439: " "unprognostic (6.89e-2)" "unprognostic (7.53e-2)" "unprognostic (9.07e-2)" "unprognostic (1.24e-1)" "unprognostic (1.69e-1)" "unprognostic (2.40e-1)" "unprognostic (2.97e-1)" "unprognostic (3.95e-1)" "unprognostic (8.32e-2)" "unprognostic (6.38e-2)" "potential prognostic unfavorable (7.68e-5)" "unprognostic (2.85e-2)" "unprognostic (1.52e-2)" "potential prognostic unfavorable (2.89e-5)" "unprognostic (2.18e-2)" "unprognostic (1.64e-1)" "unprognostic (2.93e-2)" "unprognostic (4.34e-3)" "unprognostic (6.34e-2)" "unprognostic (5.19e-2)" "unprognostic (3.17e-1)" "unprognostic (1.27e-1)" "unprognostic (1.77e-1)" "unprognostic (4.82e-2)" "unprognostic (6.16e-2)" "potential prognostic favorable (3.76e-4)" "unprognostic (5.17e-3)" "unprognostic (3.10e-2)" "unprognostic (2.22e-1)" "unprognostic (1.45e-1)" "unprognostic (1.20e-1)" STX11 ENSG00000135604 "Syntaxin 11" O75558 6 144150487-144191939 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Familial hemophagocytic lymphohistiocytosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "bone marrow: 141.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 147.8;cDC: 270.9;Kupffer cells: 222.4;Macrophages: 171.5;Mast cells: 152.6;Megakaryocytes: 265.8;Monocyte progenitors: 357.1;monocytes: 490.1;Neutrophil progenitors: 391.4;Neutrophils: 919.0;Platelets: 228.9;Suprabasal keratinocytes: 146.9" "Group enriched" "Detected in some" 4 "central nervous system macrophage: 16.9;leukocyte: 40.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "basophil: 55.8;classical monocyte: 161.7;eosinophil: 102.7;intermediate monocyte: 181.5;myeloid DC: 60.8;neutrophil: 205.0;non-classical monocyte: 200.0" "Group enriched" "Detected in all" 8 "dendritic cells: 60.8;granulocytes: 205.0;monocytes: 200.0" "Cancer enhanced" "Detected in many" "lymphoma: 15.2" "Adipose subcutaneous - Adipocytes (Subcutaneous), Prostate - Endothelial cells, Skeletal muscle - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA007992 Approved NA NA 480000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 15: Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 107 "HPA007992: " "unprognostic (2.52e-1)" "unprognostic (5.80e-3)" "unprognostic (4.30e-1)" "unprognostic (1.64e-1)" "unprognostic (3.38e-1)" "unprognostic (1.19e-1)" "unprognostic (2.37e-2)" "unprognostic (1.18e-1)" "unprognostic (3.98e-3)" "unprognostic (9.57e-2)" "unprognostic (3.23e-1)" "unprognostic (1.52e-1)" "unprognostic (2.13e-2)" "unprognostic (9.14e-2)" "unprognostic (7.91e-2)" "unprognostic (8.76e-2)" "unprognostic (1.20e-1)" "unprognostic (6.83e-2)" "unprognostic (5.74e-2)" "unprognostic (4.80e-2)" "unprognostic (3.28e-1)" "unprognostic (1.20e-1)" "unprognostic (6.73e-3)" "unprognostic (5.72e-3)" STX12 "STX13, STX14" ENSG00000117758 "Syntaxin 12" Q86Y82 1 27773219-27824443 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Parietal cells: 438.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Parietal cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041038, HPA055300" Approved Enhanced "Nucleoplasm,Golgi apparatus,Vesicles" No No 27000 "Cluster 40: Monocytes - Innate immune response" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 27: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 147 "Nucleoplasm, Golgi apparatus, Vesicles" "HPA041038: , HPA055300: " "unprognostic (7.08e-3)" "unprognostic (1.21e-1)" "unprognostic (7.68e-2)" "unprognostic (4.70e-2)" "unprognostic (3.62e-1)" "unprognostic (1.25e-1)" "unprognostic (1.75e-1)" "unprognostic (7.27e-2)" "unprognostic (2.57e-2)" "potential prognostic unfavorable (4.26e-4)" "potential prognostic favorable (1.34e-8)" "unprognostic (3.83e-3)" "unprognostic (1.37e-1)" "unprognostic (1.18e-3)" "unprognostic (2.27e-2)" "unprognostic (2.95e-1)" "unprognostic (1.35e-1)" "unprognostic (2.89e-2)" "unprognostic (1.31e-2)" "unprognostic (3.47e-2)" "unprognostic (2.76e-2)" "unprognostic (2.46e-1)" "unprognostic (2.44e-2)" "unprognostic (1.02e-1)" "unprognostic (2.04e-1)" "unprognostic (7.39e-2)" "unprognostic (9.38e-2)" "unprognostic (2.62e-2)" "unprognostic (1.09e-1)" "unprognostic (1.01e-1)" "unprognostic (1.79e-1)" STX16 "hsyn16, SYN-16, SYN16" ENSG00000124222 "Syntaxin 16" O14662 20 58651253-58679526 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 7 "Astrocytes: 39.6;Bergmann glia: 47.4;Brain excitatory neurons: 39.5;Brain inhibitory neurons: 35.4;Choroid plexus epithelial cells: 50.6;Ependymal cells: 43.7;Microglia: 50.1;Oligodendrocyte progenitor cells: 48.7;Oligodendrocytes: 53.4;Other brain neurons: 30.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041019, HPA042033" Uncertain Enhanced Vesicles NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 64: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 62: Non-specific - Plasma proteins" "Cluster 22: Non-specific - Basic cellular functions" 29 Vesicles "HPA041019: , HPA042033: " "unprognostic (3.38e-1)" "unprognostic (3.71e-2)" "unprognostic (4.80e-2)" "unprognostic (4.63e-2)" "unprognostic (3.49e-2)" "unprognostic (6.20e-2)" "unprognostic (2.39e-1)" "unprognostic (3.98e-1)" "unprognostic (1.98e-1)" "unprognostic (2.90e-1)" "potential prognostic unfavorable (4.06e-5)" "unprognostic (1.42e-1)" "unprognostic (2.66e-1)" "unprognostic (3.67e-3)" "unprognostic (3.45e-2)" "unprognostic (2.40e-1)" "unprognostic (1.01e-2)" "unprognostic (1.17e-1)" "unprognostic (1.55e-1)" "unprognostic (1.91e-1)" "unprognostic (1.14e-1)" "unprognostic (9.53e-3)" "potential prognostic unfavorable (4.05e-4)" "unprognostic (4.00e-2)" "unprognostic (1.95e-2)" "unprognostic (1.12e-3)" "unprognostic (1.24e-1)" "unprognostic (8.05e-2)" "unprognostic (5.80e-2)" "unprognostic (9.52e-2)" "unprognostic (7.53e-2)" STX17 FLJ20651 ENSG00000136874 "Syntaxin 17" P56962 9 99906654-99974534 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Autophagy, ER-Golgi transport, Host-virus interaction, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001204 Approved Uncertain Nucleoli,Cytosol NA NA "Cluster 1: T-cells - Unknown function" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 16: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Transcription" 46 "Nucleoli, Cytosol" "HPA001204: " "unprognostic (1.27e-1)" "unprognostic (4.85e-2)" "unprognostic (1.90e-1)" "unprognostic (9.56e-2)" "unprognostic (2.71e-1)" "unprognostic (4.60e-2)" "unprognostic (1.73e-2)" "unprognostic (1.33e-1)" "unprognostic (1.60e-1)" "unprognostic (4.15e-2)" "validated prognostic favorable (9.08e-6)" "validated prognostic favorable (5.41e-5)" "unprognostic (2.60e-1)" "unprognostic (1.34e-1)" "unprognostic (7.10e-3)" "unprognostic (7.34e-2)" "unprognostic (3.51e-2)" "unprognostic (1.80e-2)" "unprognostic (1.99e-1)" "unprognostic (1.50e-1)" "unprognostic (5.92e-3)" "unprognostic (4.89e-2)" "unprognostic (6.52e-2)" "unprognostic (5.29e-2)" "potential prognostic favorable (4.11e-4)" "unprognostic (8.73e-3)" "unprognostic (1.11e-1)" "unprognostic (9.72e-2)" "unprognostic (1.40e-1)" "unprognostic (1.07e-1)" "unprognostic (1.24e-1)" STX18 Ufe1 ENSG00000168818 "Syntaxin 18" Q9P2W9 4 4415742-4542346 "Essential proteins, Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 112.8" "Cell type enhanced" "Detected in all" "Endometrial ciliated cells: 392.8;Endometrial glandular cells: 452.9;Endometrial luminal cells: 463.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003019 Approved Supported "Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 72 "Endoplasmic reticulum, Plasma membrane" "HPA003019: " "unprognostic (2.27e-2)" "unprognostic (1.80e-1)" "unprognostic (7.64e-2)" "unprognostic (9.54e-2)" "unprognostic (1.45e-2)" "unprognostic (8.82e-2)" "unprognostic (3.13e-1)" "unprognostic (5.55e-3)" "unprognostic (4.86e-2)" "unprognostic (2.13e-1)" "potential prognostic favorable (6.21e-6)" "unprognostic (2.60e-3)" "unprognostic (5.54e-2)" "potential prognostic unfavorable (1.48e-6)" "unprognostic (1.88e-1)" "potential prognostic unfavorable (1.79e-4)" "unprognostic (2.51e-3)" "unprognostic (5.95e-2)" "unprognostic (1.40e-1)" "unprognostic (6.58e-2)" "unprognostic (4.42e-3)" "unprognostic (5.32e-2)" "unprognostic (2.96e-1)" "unprognostic (3.99e-2)" "unprognostic (3.59e-2)" "unprognostic (8.98e-2)" "unprognostic (4.04e-1)" "unprognostic (5.20e-2)" "unprognostic (3.38e-1)" "unprognostic (1.86e-3)" "unprognostic (1.18e-2)" STX19 MGC21382 ENSG00000178750 "Syntaxin 19" Q8N4C7 3 94014365-94028597 "Predicted intracellular proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 15.4;intestine: 12.6" "Cell type enhanced" "Detected in many" "Breast lactating cells: 57.8;Colonocytes: 73.0;Epicardial cells: 86.4;Epididymal principal cells: 47.1;Esophageal apical cells: 90.3;Esophageal suprabasal cells: 41.9;Goblet cells: 61.6;Paneth cells: 42.5;Rod photoreceptor cells: 82.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 16.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 5.9;prostate cancer: 5.4" "Colon - Colon enterocytes, Prostate - Prostate glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA030604 Uncertain Approved "Intermediate filaments,Cytosol" NA NA "Cluster 17: Intestine - Digestion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 70: Intestinal goblet cells - Mucin production" 24 "Intermediate filaments" Cytosol "HPA030604: " "unprognostic (2.31e-2)" "unprognostic (7.75e-2)" "unprognostic (4.55e-2)" "unprognostic (1.34e-1)" "unprognostic (3.90e-1)" "unprognostic (1.12e-1)" "unprognostic (1.03e-2)" "unprognostic (1.80e-1)" "unprognostic (1.69e-1)" "unprognostic (9.00e-2)" "unprognostic (1.79e-1)" "unprognostic (1.82e-1)" "unprognostic (1.23e-1)" "unprognostic (8.03e-3)" "unprognostic (7.65e-2)" "unprognostic (1.85e-1)" "unprognostic (4.62e-2)" "unprognostic (4.46e-3)" "unprognostic (5.90e-2)" "unprognostic (1.40e-2)" STX1A "HPC-1, p35-1, STX1" ENSG00000106089 "Syntaxin 1A" Q16623 7 73699206-73719672 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Exocytosis, Neurotransmitter transport, Transport" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 12 "brain: 169.5;pituitary gland: 94.1" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 47.5;Endometrial glandular cells: 27.2;Foveolar cells: 27.5;Lactotrophs: 38.1;Neuroendocrine cells: 44.0;Pancreatic islet cells: 93.5;Platelets: 93.3;Somatotrophs: 33.8" "Cell type enhanced" "Detected in all" "deep-layer intratelencephalic: 114.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Alpha cells, Pancreas - Beta cells" "Group enriched" "Detected in all" 5 "amygdala: 246.4;basal ganglia: 93.9;cerebral cortex: 354.5;hippocampal formation: 229.2;white matter: 116.1" "Group enriched" "Detected in all" 8 "amygdala: 48.7;cerebral cortex: 134.1;hippocampal formation: 113.2" "CAB008372, HPA069176" Enhanced Approved "Nuclear membrane,Vesicles" "Intracellular and membrane" Transport NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 130 Vesicles "Nuclear membrane" "CAB008372: , HPA069176: " "unprognostic (5.27e-2)" "unprognostic (1.67e-2)" "unprognostic (1.51e-1)" "unprognostic (1.98e-3)" "unprognostic (6.70e-3)" "unprognostic (1.80e-1)" "unprognostic (5.17e-3)" "unprognostic (1.31e-2)" "unprognostic (8.68e-2)" "unprognostic (9.57e-3)" "potential prognostic unfavorable (4.98e-5)" "unprognostic (4.06e-3)" "unprognostic (6.70e-2)" "validated prognostic unfavorable (5.93e-9)" "validated prognostic unfavorable (4.54e-4)" "unprognostic (8.60e-3)" "unprognostic (5.10e-3)" "potential prognostic unfavorable (8.59e-4)" "unprognostic (2.76e-2)" "unprognostic (4.83e-2)" "unprognostic (1.80e-1)" "unprognostic (8.76e-2)" "unprognostic (2.05e-2)" "unprognostic (1.80e-3)" "unprognostic (3.31e-1)" "unprognostic (1.75e-1)" "unprognostic (2.34e-3)" "unprognostic (3.79e-2)" "unprognostic (1.19e-1)" "potential prognostic unfavorable (1.32e-4)" "potential prognostic unfavorable (5.05e-7)" STX1B "STX1B1, STX1B2" ENSG00000099365 "Syntaxin 1B" P61266 16 30989256-31010638 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Neurotransmitter transport, Transport" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 15 "brain: 141.4" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 60.5;Brain inhibitory neurons: 47.8;Epicardial cells: 27.3;Gonadotrophs: 19.2;Late spermatids: 23.9;Oligodendrocyte progenitor cells: 15.7;Other brain neurons: 37.6;Retinal amacrine cells: 71.0;Retinal ganglion cells: 23.2;Retinal horizontal cells: 34.1" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in some" 6 "Glioblastoma Multiforme (TCGA): 9.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 10.9" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069176, CAB079008" Supported Approved Uncertain "Nuclear membrane,Vesicles" NA NA 24000 "Cluster 27: Cerebellum - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 26 "Nuclear membrane, Vesicles" "CAB079008: , HPA069176: " "unprognostic (4.53e-1)" "unprognostic (5.70e-2)" "unprognostic (1.62e-1)" "unprognostic (1.37e-2)" "unprognostic (6.24e-3)" "unprognostic (3.91e-2)" "unprognostic (1.58e-2)" "unprognostic (1.35e-2)" "potential prognostic favorable (3.50e-4)" "unprognostic (2.38e-1)" "unprognostic (7.67e-3)" "unprognostic (1.30e-2)" "unprognostic (2.16e-1)" STX2 "EPIM, EPM, STX2A, STX2B, STX2C" ENSG00000111450 "Syntaxin 2" P32856 12 130789600-130839254 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 111.1;Choroid plexus epithelial cells: 148.2;Early spermatids: 145.9;Endometrial ciliated cells: 149.1;Fallopian tube ciliated cells: 139.8;Late primary spermatocytes: 109.8;Late spermatids: 145.4;Respiratory ciliated cells: 153.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Endothelial cells, Skin - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069176, CAB079007" Uncertain Supported Approved "Nuclear membrane,Vesicles" NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 21: Non-specific - Metabolism" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 9 Vesicles "Nuclear membrane" "CAB079007: , HPA069176: " "unprognostic (3.48e-2)" "unprognostic (9.56e-3)" "unprognostic (5.57e-2)" "unprognostic (2.08e-1)" "unprognostic (1.15e-1)" "unprognostic (5.16e-2)" "unprognostic (6.02e-2)" "unprognostic (2.19e-1)" "unprognostic (5.41e-2)" "unprognostic (8.28e-2)" "unprognostic (1.00e-1)" "unprognostic (2.27e-1)" "unprognostic (1.48e-1)" "unprognostic (8.73e-3)" "unprognostic (3.06e-1)" "unprognostic (1.59e-1)" "potential prognostic unfavorable (8.27e-4)" "unprognostic (1.85e-3)" "unprognostic (1.84e-1)" "unprognostic (2.65e-2)" "unprognostic (2.18e-1)" "unprognostic (2.54e-2)" "unprognostic (3.03e-3)" "unprognostic (7.97e-2)" "unprognostic (1.25e-1)" "unprognostic (7.47e-3)" "unprognostic (1.20e-1)" "unprognostic (2.00e-2)" "unprognostic (1.64e-1)" "unprognostic (7.92e-3)" "unprognostic (6.25e-2)" STX3 STX3A ENSG00000166900 "Syntaxin 3" Q13277 11 59713456-59805882 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "retina: 290.0" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 250.5;Mast cells: 291.9;Neutrophil progenitors: 281.6;Neutrophils: 754.5;Retinal bipolar cells: 300.6;Rod photoreceptor cells: 321.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "basophil: 42.5;eosinophil: 74.2;neutrophil: 60.9" "Lineage enriched" "Detected in many" 10 "granulocytes: 74.2" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Spleen - Neutrophils_2, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002191, HPA069176" Approved Uncertain "Nuclear membrane,Vesicles" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 42: Retina - Visual perception" "Cluster 37: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 76 Vesicles "Nuclear membrane" "HPA002191: , HPA069176: " "potential prognostic favorable (5.24e-5)" "unprognostic (3.95e-2)" "unprognostic (2.73e-2)" "unprognostic (2.01e-3)" "unprognostic (2.74e-2)" "unprognostic (1.79e-2)" "unprognostic (4.43e-2)" "unprognostic (2.01e-1)" "unprognostic (5.19e-2)" "unprognostic (1.42e-3)" "potential prognostic favorable (3.67e-7)" "unprognostic (2.25e-2)" "unprognostic (3.54e-2)" "potential prognostic unfavorable (2.14e-6)" "unprognostic (2.56e-3)" "unprognostic (3.08e-2)" "unprognostic (2.48e-2)" "unprognostic (9.56e-3)" "unprognostic (2.14e-1)" "unprognostic (2.57e-1)" "unprognostic (1.77e-2)" "unprognostic (4.12e-3)" "unprognostic (1.39e-1)" "unprognostic (3.86e-2)" "unprognostic (1.10e-1)" "unprognostic (6.16e-2)" "unprognostic (3.09e-1)" "unprognostic (2.56e-1)" "unprognostic (1.46e-1)" "unprognostic (2.81e-2)" "unprognostic (7.44e-2)" STX4 "p35-2, STX4A" ENSG00000103496 "Syntaxin 4" Q12846 16 31032889-31042975 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hearing, Neurotransmitter transport, Transport" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 65.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001330 Approved Approved "Plasma membrane" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 100 "Plasma membrane" "HPA001330: " "unprognostic (3.67e-1)" "unprognostic (2.06e-2)" "unprognostic (9.91e-3)" "unprognostic (2.81e-2)" "unprognostic (1.72e-1)" "unprognostic (2.17e-1)" "unprognostic (1.24e-1)" "unprognostic (2.80e-1)" "unprognostic (2.84e-1)" "unprognostic (1.50e-1)" "unprognostic (2.81e-1)" "unprognostic (2.34e-1)" "unprognostic (3.35e-2)" "unprognostic (2.24e-3)" "unprognostic (5.80e-2)" "unprognostic (1.31e-1)" "unprognostic (5.69e-3)" "unprognostic (3.29e-1)" "unprognostic (9.89e-2)" "unprognostic (6.76e-2)" "unprognostic (1.27e-1)" "unprognostic (2.02e-3)" "unprognostic (4.59e-3)" "unprognostic (1.48e-1)" "unprognostic (1.00e-1)" "unprognostic (3.32e-1)" "unprognostic (2.03e-2)" "unprognostic (2.43e-1)" "unprognostic (3.08e-2)" "unprognostic (2.29e-1)" "unprognostic (1.70e-1)" STX5 "SED5, STX5A" ENSG00000162236 "Syntaxin 5" Q13190 11 62806860-62832051 "Essential proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 323.5;Syncytiotrophoblasts: 318.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001358 Uncertain Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 55: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 90 "Golgi apparatus" Nucleoplasm "HPA001358: " "unprognostic (1.09e-1)" "unprognostic (4.09e-1)" "unprognostic (2.46e-2)" "unprognostic (9.37e-2)" "unprognostic (4.08e-2)" "unprognostic (7.79e-2)" "unprognostic (1.19e-1)" "unprognostic (6.92e-2)" "unprognostic (2.38e-1)" "unprognostic (1.89e-1)" "potential prognostic favorable (7.85e-5)" "unprognostic (1.81e-1)" "unprognostic (6.11e-3)" "unprognostic (4.18e-3)" "unprognostic (3.94e-2)" "unprognostic (7.56e-2)" "potential prognostic unfavorable (3.88e-4)" "unprognostic (2.46e-1)" "unprognostic (2.93e-2)" "unprognostic (1.06e-1)" "unprognostic (3.95e-2)" "unprognostic (1.41e-2)" "unprognostic (8.00e-2)" "unprognostic (3.68e-1)" "unprognostic (3.19e-1)" "unprognostic (7.56e-2)" "unprognostic (1.13e-1)" "unprognostic (6.38e-2)" "unprognostic (3.88e-1)" "unprognostic (7.19e-2)" "unprognostic (2.07e-1)" STX6 ENSG00000135823 "Syntaxin 6" O43752 1 180972712-181023121 "Plasma proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 124.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038557, HPA038558" Approved Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 34: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 125 "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA038557: , HPA038558: " "unprognostic (6.52e-2)" "unprognostic (3.24e-3)" "unprognostic (3.92e-2)" "unprognostic (1.37e-2)" "unprognostic (3.55e-3)" "unprognostic (1.39e-1)" "unprognostic (1.92e-1)" "unprognostic (1.57e-3)" "unprognostic (3.07e-2)" "unprognostic (1.76e-3)" "potential prognostic favorable (9.02e-4)" "unprognostic (1.92e-1)" "unprognostic (1.03e-3)" "potential prognostic unfavorable (2.21e-5)" "unprognostic (2.13e-2)" "unprognostic (5.44e-2)" "unprognostic (4.79e-2)" "unprognostic (1.25e-1)" "unprognostic (5.03e-3)" "unprognostic (1.81e-1)" "potential prognostic unfavorable (7.22e-4)" "unprognostic (3.19e-2)" "unprognostic (1.88e-1)" "unprognostic (1.14e-1)" "unprognostic (1.93e-2)" "unprognostic (1.46e-1)" "unprognostic (1.30e-1)" "unprognostic (2.30e-1)" "unprognostic (6.31e-2)" "unprognostic (5.83e-2)" "unprognostic (1.70e-2)" STX7 ENSG00000079950 "Syntaxin 7" O15400 6 132445867-132513198 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "B-cells: 318.2;Hofbauer cells: 364.5;Melanocytes: 364.4;Microglia: 442.5;Neutrophils: 387.1" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 569.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 53.6;classical monocyte: 51.6;eosinophil: 49.2;intermediate monocyte: 58.1;memory B-cell: 86.2;myeloid DC: 61.6;naive B-cell: 107.2;neutrophil: 83.5;non-classical monocyte: 61.9;plasmacytoid DC: 74.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001467, CAB062564" Enhanced Supported Lysosomes NA NA 540000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 24: Neutrophils - Innate immunity signal integration" 152 Lysosomes "CAB062564: , HPA001467: " "unprognostic (4.36e-2)" "unprognostic (1.94e-2)" "unprognostic (5.61e-2)" "potential prognostic unfavorable (6.87e-6)" "unprognostic (2.00e-1)" "unprognostic (2.48e-1)" "unprognostic (2.70e-1)" "unprognostic (2.24e-1)" "unprognostic (4.09e-1)" "unprognostic (4.07e-3)" "potential prognostic favorable (1.82e-10)" "unprognostic (2.99e-3)" "unprognostic (3.30e-2)" "potential prognostic unfavorable (6.53e-5)" "unprognostic (3.51e-2)" "unprognostic (2.01e-1)" "unprognostic (3.75e-1)" "potential prognostic unfavorable (1.12e-4)" "unprognostic (7.30e-3)" "unprognostic (5.58e-3)" "unprognostic (1.47e-3)" "unprognostic (2.46e-2)" "unprognostic (5.33e-2)" "unprognostic (3.90e-1)" "unprognostic (1.53e-2)" "unprognostic (1.21e-1)" "unprognostic (9.52e-2)" "unprognostic (1.61e-1)" "unprognostic (3.52e-1)" "unprognostic (2.75e-1)" "unprognostic (1.02e-1)" STX8 CARB ENSG00000170310 "Syntaxin 8" Q9UNK0 17 9250471-9576591 "Predicted intracellular proteins, Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Late spermatids: 1546.7;Oocytes: 1174.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001540 Approved Approved Vesicles,Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 67: Testis - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 144 Vesicles Cytosol "HPA001540: " "unprognostic (3.41e-3)" "unprognostic (6.78e-3)" "unprognostic (1.73e-2)" "potential prognostic favorable (7.34e-4)" "unprognostic (2.36e-1)" "unprognostic (1.32e-1)" "unprognostic (3.18e-1)" "unprognostic (7.17e-2)" "unprognostic (2.47e-3)" "unprognostic (1.78e-2)" "unprognostic (1.00e-1)" "unprognostic (2.14e-2)" "unprognostic (2.52e-2)" "unprognostic (3.52e-2)" "unprognostic (2.05e-1)" "unprognostic (2.67e-2)" "unprognostic (1.43e-1)" "unprognostic (9.74e-2)" "unprognostic (3.11e-2)" "unprognostic (3.17e-1)" "unprognostic (5.50e-3)" "unprognostic (2.66e-2)" "unprognostic (2.43e-3)" "unprognostic (3.73e-1)" "unprognostic (8.02e-2)" "unprognostic (2.33e-1)" "unprognostic (3.75e-1)" "unprognostic (2.81e-1)" "unprognostic (5.59e-2)" "unprognostic (1.15e-1)" "unprognostic (1.28e-1)" STXBP1 "hUNC18, MUNC18-1, nSec1, rbSec1, UNC18" ENSG00000136854 "Syntaxin binding protein 1" P61764 9 127579370-127696027 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 252.0;retina: 188.2" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 304.0;Cone photoreceptor cells: 285.7;Corticotrophs: 227.6;Gonadotrophs: 315.4;Lactotrophs: 382.5;Retinal amacrine cells: 250.4;Rod photoreceptor cells: 457.6;Somatotrophs: 464.6;Thyrotrophs: 295.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 105.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "skin cancer: 120.7" "Minor Salivary Gland - Endothelial cells, Pituitary gland - Lactotropes, Prostate - Fibroblasts, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008209, HPA023483, CAB034434" Enhanced Uncertain "Nucleoplasm,Nucleoli,Basal body,Cytosol" NA NA 63000 "Cluster 31: T-cells - T-cell receptor" "Cluster 27: Cerebellum - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 36 Nucleoplasm "Nucleoli, Basal body, Cytosol" "CAB034434: , HPA008209: , HPA023483: " "unprognostic (4.17e-3)" "unprognostic (1.23e-2)" "unprognostic (2.92e-1)" "unprognostic (1.18e-1)" "unprognostic (4.42e-2)" "potential prognostic unfavorable (6.52e-7)" "unprognostic (1.41e-1)" "unprognostic (5.81e-3)" "potential prognostic unfavorable (2.14e-4)" "unprognostic (1.08e-1)" "validated prognostic favorable (5.80e-6)" "validated prognostic favorable (1.72e-4)" "unprognostic (7.06e-2)" "potential prognostic unfavorable (3.49e-4)" "unprognostic (5.08e-2)" "unprognostic (8.08e-3)" "unprognostic (2.35e-1)" "potential prognostic unfavorable (6.37e-4)" "unprognostic (1.21e-1)" "unprognostic (2.26e-2)" "unprognostic (3.77e-1)" "unprognostic (1.93e-3)" "unprognostic (3.24e-1)" "unprognostic (3.51e-2)" "unprognostic (3.21e-3)" "unprognostic (4.43e-2)" "unprognostic (2.59e-1)" "unprognostic (1.31e-1)" "unprognostic (3.83e-2)" "unprognostic (4.83e-1)" "unprognostic (2.30e-3)" STXBP2 "Hunc18b, MUNC18-2, Unc18-2, UNC18B" ENSG00000076944 "Syntaxin binding protein 2" Q15833 19 7636772-7647873 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Exocytosis, Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 153.1" "Cell type enhanced" "Detected in many" "Late spermatids: 320.5;Megakaryocytes: 253.4;monocytes: 273.8;Neutrophil progenitors: 300.6;Neutrophils: 901.0;Platelets: 480.7" "Group enriched" "Detected in some" 5 "central nervous system macrophage: 20.7;choroid plexus epithelial cell: 8.2;leukocyte: 31.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 837.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Breast glandular cells, Heart muscle - Macrophages, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Somatotropes, Skin - Keratinocyte (other), Spleen - Neutrophils_2, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA015564, HPA063868" Approved Enhanced Cytosol No No 900000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 5: Spleen - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 7 Cytosol "HPA015564: , HPA063868: " "unprognostic (9.74e-2)" "unprognostic (2.67e-1)" "unprognostic (2.93e-1)" "unprognostic (1.93e-2)" "unprognostic (1.03e-1)" "unprognostic (4.85e-2)" "unprognostic (5.97e-2)" "unprognostic (3.60e-2)" "unprognostic (4.87e-2)" "unprognostic (1.58e-1)" "unprognostic (7.00e-2)" "unprognostic (6.99e-3)" "unprognostic (7.01e-2)" "unprognostic (3.90e-3)" "unprognostic (2.99e-2)" "unprognostic (3.38e-2)" "unprognostic (6.08e-2)" "unprognostic (2.95e-1)" "unprognostic (1.77e-1)" "unprognostic (6.98e-2)" "unprognostic (1.84e-1)" "unprognostic (2.35e-2)" "unprognostic (1.44e-1)" "unprognostic (8.45e-2)" "unprognostic (1.54e-1)" "unprognostic (1.56e-1)" "unprognostic (2.12e-1)" "unprognostic (5.65e-2)" "unprognostic (9.54e-2)" "unprognostic (5.16e-2)" "unprognostic (5.88e-2)" STXBP3 UNC-18C ENSG00000116266 "Syntaxin binding protein 3" O00186 1 108746674-108809523 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 392.4" "Cell type enhanced" "Detected in all" "oligodendrocyte: 335.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027225 Approved Approved Nucleoplasm,Cytosol NA NA 10000 "Cluster 35: Neutrophils - Protein binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 24: Neutrophils - Innate immunity signal integration" 10 Nucleoplasm Cytosol "HPA027225: " "unprognostic (9.62e-2)" "unprognostic (1.91e-1)" "unprognostic (1.30e-2)" "unprognostic (1.99e-1)" "potential prognostic favorable (5.23e-5)" "unprognostic (2.86e-2)" "unprognostic (2.31e-1)" "unprognostic (2.69e-1)" "unprognostic (8.66e-2)" "unprognostic (1.82e-2)" "potential prognostic favorable (1.08e-5)" "unprognostic (4.06e-3)" "unprognostic (3.52e-1)" "potential prognostic unfavorable (8.74e-4)" "unprognostic (1.05e-1)" "unprognostic (2.35e-2)" "unprognostic (2.63e-2)" "unprognostic (6.27e-2)" "unprognostic (1.46e-1)" "unprognostic (2.36e-1)" "unprognostic (1.91e-1)" "unprognostic (5.05e-2)" "unprognostic (1.61e-1)" "unprognostic (1.60e-1)" "unprognostic (2.90e-2)" "unprognostic (3.11e-1)" "unprognostic (6.45e-2)" "unprognostic (1.77e-1)" "unprognostic (1.71e-1)" "unprognostic (2.95e-1)" "unprognostic (4.51e-2)" STXBP4 "MGC50337, Synip" ENSG00000166263 "Syntaxin binding protein 4" Q6ZWJ1 17 54968727-55173632 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 197.5;Cone photoreceptor cells: 204.9;Distal convoluted tubule cells: 229.5;Ependymal cells: 313.9;Loop of henle epithelial cells: 201.0;Renal connecting tubule cells: 212.3" "Cell type enhanced" "Detected in all" "ependymal cell: 343.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007760, HPA022138, HPA022888, HPA024227" Approved Approved "Plasma membrane,Cytosol" No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 110: Mural cells - ECM organization" 10 "Plasma membrane" Cytosol "CAB007760: , HPA022138: , HPA022888: , HPA024227: " "unprognostic (2.51e-2)" "unprognostic (3.23e-2)" "unprognostic (5.98e-2)" "unprognostic (1.02e-1)" "unprognostic (1.27e-2)" "unprognostic (1.02e-1)" "unprognostic (3.70e-2)" "unprognostic (2.21e-1)" "unprognostic (3.22e-1)" "unprognostic (3.01e-2)" "potential prognostic favorable (1.33e-4)" "unprognostic (4.78e-3)" "unprognostic (2.56e-2)" "unprognostic (3.95e-2)" "unprognostic (1.07e-1)" "unprognostic (6.54e-2)" "unprognostic (1.80e-1)" "unprognostic (1.22e-2)" "unprognostic (1.28e-1)" "unprognostic (1.36e-1)" "unprognostic (1.87e-1)" "unprognostic (5.18e-2)" "unprognostic (5.06e-2)" "unprognostic (1.71e-1)" "potential prognostic favorable (3.95e-4)" "unprognostic (2.86e-1)" "unprognostic (1.17e-1)" "unprognostic (1.65e-1)" "unprognostic (3.11e-1)" "unprognostic (1.06e-1)" STXBP5 "LLGL3, tomosyn, tomosyn-1" ENSG00000164506 "Syntaxin binding protein 5" Q5T5C0 6 147204180-147391010 "Predicted intracellular proteins" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 35.8" "Cell type enhanced" "Detected in all" "Megakaryocyte progenitors: 799.7;Megakaryocyte-Erythroid progenitors: 830.1;Neutrophil progenitors: 1587.5;Neutrophils: 1611.8;Prostatic glandular cells: 759.6;Retinal amacrine cells: 692.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 1.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039991, HPA049727, CAB079016" Enhanced Supported Enhanced Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 47: Leukemia - Hemostasis" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 3 Cytosol "CAB079016: , HPA039991: , HPA049727: " "unprognostic (5.34e-2)" "unprognostic (8.73e-3)" "unprognostic (3.72e-2)" "potential prognostic unfavorable (1.62e-4)" "unprognostic (4.47e-2)" "unprognostic (1.61e-2)" "unprognostic (2.37e-1)" "unprognostic (1.47e-2)" "unprognostic (1.41e-1)" "unprognostic (7.79e-2)" "unprognostic (3.03e-2)" "unprognostic (1.87e-1)" "unprognostic (1.03e-2)" "unprognostic (2.64e-3)" "unprognostic (9.26e-2)" "potential prognostic unfavorable (9.00e-4)" "unprognostic (5.38e-2)" "unprognostic (3.55e-1)" "unprognostic (2.71e-1)" "unprognostic (4.69e-2)" "unprognostic (1.89e-1)" "unprognostic (1.96e-1)" "unprognostic (2.12e-2)" "unprognostic (2.54e-1)" "unprognostic (5.97e-3)" "unprognostic (2.32e-1)" "unprognostic (4.79e-2)" "unprognostic (2.11e-1)" "unprognostic (1.12e-1)" "unprognostic (9.52e-2)" "unprognostic (8.60e-2)" STXBP5L "KIAA1006, LLGL4, tomosyn-2" ENSG00000145087 "Syntaxin binding protein 5L" Q9Y2K9 3 120908072-121424761 "Predicted intracellular proteins" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 24.4;thyroid gland: 7.1" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 425.5;Brain excitatory neurons: 2144.9;Brain inhibitory neurons: 966.1;Cone photoreceptor cells: 494.8;Corticotrophs: 578.9;Early primary spermatocytes: 380.3;Lactotrophs: 716.7;Neuroendocrine cells: 322.7;Oligodendrocyte progenitor cells: 477.2;Other brain neurons: 463.1;Retinal amacrine cells: 576.4;Retinal bipolar cells: 429.0;Somatotrophs: 594.5;Thyrotrophs: 740.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Kidney Chromophobe (TCGA): 3.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 6.8;Rhabdoid: 6.1" "Adrenal gland - Adrenal cortex cells, Pancreas - Alpha cells, Pancreas - Beta cells, Pituitary gland - Lactotropes, Prostate - Smooth muscle cells, Stomach - Gastric enteroendocrine cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 37: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 35: Neurons - Synaptic function & neurogenesis" 2 "unprognostic (1.50e-1)" "unprognostic (3.83e-2)" "potential prognostic unfavorable (5.03e-5)" "unprognostic (4.05e-1)" "unprognostic (3.55e-3)" STXBP6 "amisyn, HSPC156" ENSG00000168952 "Syntaxin binding protein 6" Q8NFX7 14 24809454-25050147 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Enterocytes: 253.0;Epididymal clear cells: 298.0;Goblet cells: 298.7;Mast cells: 462.2;Melanocytes: 357.4;Oligodendrocytes: 259.5;Pancreatic acinar cells: 370.7" "Cell type enhanced" "Detected in many" "endothelial cell: 852.5;hippocampal dentate gyrus: 674.7" "Cancer enhanced" "Detected in all" "Uterine Corpus Endometrial Carcinoma (TCGA): 77.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003552, HPA074869" Approved NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 104: Brain endothelial cells - Blood brain barrier" 3 "HPA003552: , HPA074869: " "unprognostic (9.06e-2)" "unprognostic (1.57e-1)" "unprognostic (5.15e-2)" "unprognostic (2.61e-1)" "unprognostic (1.23e-1)" "unprognostic (2.06e-2)" "unprognostic (1.28e-1)" "unprognostic (4.06e-2)" "unprognostic (1.32e-1)" "unprognostic (3.85e-1)" "unprognostic (1.82e-1)" "unprognostic (3.45e-1)" "unprognostic (2.16e-1)" "unprognostic (4.57e-2)" "unprognostic (7.86e-2)" "unprognostic (3.76e-1)" "unprognostic (1.39e-1)" "unprognostic (3.24e-3)" "unprognostic (1.46e-3)" "unprognostic (5.19e-2)" "unprognostic (3.04e-1)" "unprognostic (6.88e-2)" "unprognostic (2.03e-2)" "unprognostic (4.18e-2)" "unprognostic (5.87e-2)" "potential prognostic unfavorable (8.67e-4)" "unprognostic (9.49e-3)" "unprognostic (8.70e-2)" "unprognostic (1.73e-1)" "unprognostic (2.16e-1)" "potential prognostic favorable (5.68e-4)" STYK1 "DKFZp761P1010, NOK, SuRTK106" ENSG00000060140 "Serine/threonine/tyrosine kinase 1" Q6J9G0 12 10618923-10674318 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 16.0;stomach 1: 16.5" "Cell type enhanced" "Detected in many" "Colonocytes: 53.8;Esophageal apical cells: 76.6;Foveolar cells: 113.8;Goblet cells: 46.5;Lactotrophs: 49.0;Papillary tip epithelial cells: 45.4;Prostatic club cells: 64.9;Prostatic glandular cells: 90.6;Prostatic hillock cells: 68.1;Urothelial cells: 101.7" "Cell type enhanced" "Detected in many" "upper-layer intratelencephalic: 58.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "NK-cell: 12.5" "Lineage enriched" "Detected in many" 7 "NK-cells: 12.5" "Low cancer specificity" "Detected in many" "Adrenal gland - T-cells, Breast - Breast glandular cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Lactotropes, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells" "Region enhanced" "Detected in single" "basal ganglia: 2.3" "Not detected" "Not detected" "HPA040468, HPA048569" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 17: Intestine - Digestion" "Cluster 53: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 69: Urothelial cells - Basic cellular functions" 20 "Plasma membrane" Nucleoplasm "HPA040468: , HPA048569: " "unprognostic (1.30e-1)" "unprognostic (6.54e-2)" "unprognostic (1.86e-2)" "unprognostic (2.79e-1)" "unprognostic (3.84e-2)" "unprognostic (1.49e-1)" "unprognostic (3.13e-1)" "unprognostic (5.76e-2)" "potential prognostic unfavorable (5.26e-4)" "unprognostic (1.30e-2)" "unprognostic (1.94e-2)" "unprognostic (3.63e-2)" "unprognostic (2.20e-1)" "potential prognostic favorable (3.50e-4)" "unprognostic (3.04e-3)" "unprognostic (8.73e-2)" "unprognostic (3.80e-2)" "unprognostic (2.51e-2)" "unprognostic (1.17e-2)" "unprognostic (7.99e-2)" "unprognostic (1.32e-1)" "unprognostic (2.13e-2)" STYX ENSG00000198252 "Serine/threonine/tyrosine interacting protein" Q8WUJ0 14 52730166-52774989 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 97.6;Late primary spermatocytes: 147.6;Late spermatids: 133.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA040290 Uncertain Approved Nucleoplasm NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 9: T-cells - Adaptive immunity: Regulation" 11 Nucleoplasm "HPA040290: " "unprognostic (8.48e-2)" "unprognostic (6.27e-2)" "unprognostic (1.31e-2)" "unprognostic (9.82e-2)" "unprognostic (1.49e-1)" "unprognostic (7.59e-2)" "unprognostic (4.03e-1)" "unprognostic (2.39e-3)" "unprognostic (2.92e-1)" "unprognostic (1.41e-3)" "unprognostic (1.63e-3)" "unprognostic (4.04e-2)" "unprognostic (3.70e-1)" "unprognostic (1.02e-1)" "unprognostic (1.40e-1)" "potential prognostic unfavorable (8.73e-5)" "unprognostic (7.22e-3)" "unprognostic (2.57e-2)" "unprognostic (3.60e-2)" "unprognostic (2.35e-1)" "unprognostic (4.19e-2)" "unprognostic (1.63e-2)" "unprognostic (4.56e-3)" "unprognostic (1.41e-1)" "unprognostic (1.50e-1)" "unprognostic (3.15e-2)" "unprognostic (6.20e-2)" "unprognostic (5.41e-3)" "unprognostic (1.11e-1)" "unprognostic (4.51e-3)" "unprognostic (1.66e-1)" STYXL1 "DUSP24, MK-STYX" ENSG00000127952 "Serine/threonine/tyrosine interacting like 1" Q9Y6J8 7 75996338-76048004 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 170.8;Late primary spermatocytes: 116.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA050261 Uncertain NA No "Cluster 42: Non-specific - Vesicular transport" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 34: Non-specific - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 8: Non-specific - Secretory pathway" "HPA050261: " "unprognostic (2.16e-1)" "unprognostic (1.04e-1)" "unprognostic (1.27e-1)" "unprognostic (2.14e-3)" "unprognostic (2.90e-1)" "unprognostic (1.80e-1)" "unprognostic (2.14e-3)" "unprognostic (8.95e-2)" "unprognostic (1.96e-3)" "unprognostic (1.11e-2)" "unprognostic (9.97e-2)" "unprognostic (1.13e-1)" "unprognostic (1.17e-1)" "potential prognostic unfavorable (6.81e-6)" "unprognostic (2.87e-3)" "unprognostic (1.35e-2)" "potential prognostic unfavorable (3.97e-4)" "unprognostic (1.13e-1)" "unprognostic (7.56e-3)" "unprognostic (8.23e-2)" "unprognostic (2.45e-1)" "unprognostic (2.18e-2)" "unprognostic (4.22e-3)" "unprognostic (5.85e-2)" "unprognostic (1.91e-1)" "unprognostic (1.20e-1)" "unprognostic (1.82e-1)" "unprognostic (3.44e-2)" "unprognostic (3.88e-2)" "unprognostic (1.87e-1)" "unprognostic (1.51e-1)" STYXL2 DUSP27 ENSG00000198842 "Serine/threonine/tyrosine interacting like 2" Q5VZP5 1 167094075-167129165 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "heart muscle: 59.5;skeletal muscle: 107.3;tongue: 50.5" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 59.1;Hofbauer cells: 47.3;Myonuclei: 261.7;Thymic myoid cells: 175.4" "Cell type enriched" "Detected in some" 8 "central nervous system macrophage: 19.4" "Group enriched" "Detected in some" 6 "Colon Adenocarcinoma (TCGA): 15.6;Rectum Adenocarcinoma (TCGA): 20.4;Stomach Adenocarcinoma (TCGA): 5.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "Bile duct cancer: 26.1;colorectal cancer: 26.8" "Adrenal gland - Macrophages, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA012912 Approved Nucleoplasm NA NA "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 53: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 1 Nucleoplasm "HPA012912: " "unprognostic (3.20e-1)" "unprognostic (2.20e-1)" "unprognostic (1.50e-2)" "unprognostic (8.73e-3)" "unprognostic (3.02e-3)" "unprognostic (5.97e-2)" "unprognostic (4.09e-2)" "unprognostic (2.59e-2)" "unprognostic (4.71e-2)" "unprognostic (5.93e-2)" SUB1 "p14, p15, PC4" ENSG00000113387 "SUB1 regulator of transcription" P53999 5 32531633-32604079 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1080.8;Plasma cells: 1720.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Mitotic cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001311, CAB015351" Supported Supported Nucleoplasm,Nucleoli NA NA 140000 "Cluster 32: Basophils - Transcription" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 14: Neurons - Synaptic function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 44: Plasma cells - Antibody production & secretion" 58 "Nucleoplasm, Nucleoli" "CAB015351: , HPA001311: " "unprognostic (3.95e-2)" "unprognostic (8.94e-2)" "unprognostic (8.41e-2)" "unprognostic (1.53e-1)" "unprognostic (1.00e-1)" "unprognostic (2.32e-3)" "unprognostic (1.66e-1)" "unprognostic (2.97e-1)" "unprognostic (5.29e-3)" "unprognostic (3.83e-3)" "unprognostic (1.57e-3)" "unprognostic (3.68e-1)" "unprognostic (9.46e-2)" "potential prognostic unfavorable (4.85e-5)" "unprognostic (4.22e-2)" "unprognostic (1.50e-1)" "unprognostic (1.31e-1)" "unprognostic (1.13e-2)" "unprognostic (1.60e-1)" "unprognostic (4.58e-3)" "unprognostic (3.27e-2)" "unprognostic (3.72e-2)" "potential prognostic unfavorable (8.53e-5)" "unprognostic (3.49e-1)" "unprognostic (4.34e-2)" "unprognostic (1.55e-1)" "unprognostic (1.04e-2)" "unprognostic (1.65e-2)" "unprognostic (2.26e-2)" "unprognostic (3.12e-2)" "unprognostic (1.23e-1)" SUCLA2 LINC00444 ENSG00000136143 "Succinate-CoA ligase ADP-forming subunit beta" Q9P2R7 13 47745736-48037968 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" Ligase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 217.4;tongue: 253.9" "Cell type enhanced" "Detected in all" "Early spermatids: 423.7;Late spermatids: 485.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Minor Salivary Gland - Endothelial cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039435, HPA039536, HPA061528" Enhanced Supported Enhanced Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 34: Non-specific - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 23 Mitochondria "HPA039435: , HPA039536: , HPA061528: " "unprognostic (1.55e-1)" "unprognostic (3.11e-2)" "unprognostic (7.58e-3)" "unprognostic (3.01e-3)" "unprognostic (1.42e-1)" "unprognostic (1.68e-1)" "unprognostic (6.25e-2)" "unprognostic (3.42e-1)" "unprognostic (1.10e-2)" "unprognostic (2.01e-2)" "validated prognostic favorable (7.55e-13)" "validated prognostic favorable (6.23e-4)" "potential prognostic favorable (3.05e-4)" "unprognostic (1.33e-1)" "unprognostic (7.60e-3)" "potential prognostic unfavorable (6.29e-4)" "unprognostic (1.20e-2)" "unprognostic (1.33e-1)" "unprognostic (7.21e-2)" "unprognostic (3.21e-2)" "unprognostic (3.49e-3)" "unprognostic (5.00e-2)" "unprognostic (2.29e-1)" "unprognostic (3.34e-1)" "unprognostic (2.22e-2)" "unprognostic (7.94e-2)" "unprognostic (1.18e-2)" "unprognostic (2.62e-1)" "unprognostic (2.88e-1)" "unprognostic (3.64e-1)" "unprognostic (6.88e-2)" SUCLG1 ENSG00000163541 "Succinate-CoA ligase GDP/ADP-forming subunit alpha" P53597 2 84423528-84460045 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" Ligase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 516.6" "Cell type enhanced" "Detected in all" "Enteric stem cells: 398.2;Enteric transient amplifying cells: 434.9;Enterocytes: 620.3;Esophageal apical cells: 644.6;Esophageal suprabasal cells: 410.4;Parietal cells: 424.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036683, HPA036684" Enhanced Approved "Plasma membrane,Mitochondria,Cytosol" NA NA 170000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 97: Non-specific - Cellular respiration" 8 Mitochondria "Plasma membrane, Cytosol" "HPA036683: , HPA036684: " "unprognostic (1.91e-2)" "unprognostic (5.94e-3)" "unprognostic (6.16e-2)" "unprognostic (1.06e-2)" "unprognostic (1.16e-1)" "unprognostic (1.64e-2)" "unprognostic (3.44e-2)" "unprognostic (2.50e-2)" "unprognostic (2.36e-1)" "unprognostic (6.68e-2)" "potential prognostic favorable (1.23e-7)" "unprognostic (3.39e-2)" "unprognostic (4.83e-3)" "unprognostic (1.31e-2)" "unprognostic (2.17e-2)" "unprognostic (4.40e-2)" "unprognostic (4.97e-1)" "unprognostic (3.66e-2)" "unprognostic (1.29e-1)" "unprognostic (1.52e-1)" "unprognostic (1.53e-1)" "unprognostic (2.38e-1)" "unprognostic (1.64e-1)" "unprognostic (1.21e-1)" "unprognostic (8.58e-2)" "unprognostic (1.21e-2)" "unprognostic (1.65e-1)" "unprognostic (2.16e-1)" "unprognostic (1.69e-1)" "unprognostic (1.53e-1)" "unprognostic (3.96e-2)" SUCLG2 ENSG00000172340 "Succinate-CoA ligase GDP-forming subunit beta" Q96I99 3 67360460-67654612 "Citric acid cycle related proteins, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 259.9" "Cell type enhanced" "Detected in all" "Hepatocytes: 623.4;Parietal cells: 1196.9" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 358.3;leukocyte: 376.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Stomach - Parietal cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046705, HPA051998" Enhanced Approved "Plasma membrane,Mitochondria" NA NA 270000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 76: Non-specific - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 97: Non-specific - Cellular respiration" 10 Mitochondria "Plasma membrane" "HPA046705: , HPA051998: " "unprognostic (1.46e-3)" "unprognostic (1.67e-1)" "unprognostic (1.04e-2)" "unprognostic (6.11e-3)" "potential prognostic favorable (2.22e-5)" "unprognostic (2.43e-2)" "unprognostic (9.36e-2)" "potential prognostic unfavorable (8.31e-5)" "unprognostic (8.47e-2)" "unprognostic (6.18e-2)" "potential prognostic favorable (1.22e-7)" "unprognostic (9.03e-3)" "potential prognostic favorable (7.56e-4)" "unprognostic (4.43e-2)" "unprognostic (7.52e-3)" "unprognostic (2.15e-2)" "unprognostic (3.43e-2)" "unprognostic (1.01e-1)" "unprognostic (2.89e-2)" "unprognostic (2.09e-1)" "unprognostic (3.17e-2)" "unprognostic (5.21e-3)" "unprognostic (1.27e-2)" "unprognostic (8.82e-3)" "unprognostic (3.45e-2)" "unprognostic (3.79e-2)" "unprognostic (7.50e-2)" "unprognostic (2.98e-1)" "unprognostic (1.54e-1)" "unprognostic (2.38e-2)" "unprognostic (5.47e-3)" SUCNR1 GPR91 ENSG00000198829 "Succinate receptor 1" Q9BXA5 3 151873643-151884619 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "kidney: 37.3" "Cell type enhanced" "Detected in some" "Hofbauer cells: 32.8;Kupffer cells: 120.9;Macrophages: 28.9;Microglia: 34.1;Neutrophil progenitors: 74.9;Platelets: 94.7;Renal connecting tubule cells: 15.9;Respiratory ionocytes: 25.4;Tuft cells: 23.1" "Cell type enriched" "Detected in single" 116 "central nervous system macrophage: 40.2" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 10.2" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 11.9;Rhabdoid: 14.1" "Breast - Endothelial cells, Spleen - Macrophages, Thyroid gland - Fibroblasts" "Not detected" "Not detected" "Not detected" "Not detected" CAB022745 Uncertain NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 72: Kidney - Transmembrane transport" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 5: Rhabdoid - Unknown function" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 2 "CAB022745: " "unprognostic (2.32e-1)" "unprognostic (2.63e-1)" "unprognostic (1.12e-2)" "unprognostic (1.18e-1)" "unprognostic (1.64e-1)" "unprognostic (1.24e-1)" "potential prognostic favorable (8.07e-5)" "unprognostic (2.08e-2)" "potential prognostic unfavorable (5.61e-4)" "unprognostic (2.51e-1)" "unprognostic (6.90e-2)" "unprognostic (1.03e-1)" "unprognostic (6.24e-2)" "unprognostic (2.06e-1)" "unprognostic (3.60e-1)" "unprognostic (1.11e-1)" "unprognostic (4.33e-2)" "unprognostic (7.11e-2)" "potential prognostic favorable (8.06e-4)" "unprognostic (2.31e-1)" "unprognostic (5.05e-2)" "unprognostic (1.01e-1)" SUCO "C1orf9, CH1, OPT, SLP1" ENSG00000094975 "SUN domain containing ossification factor" Q9UBS9 1 172532349-172611833 "Predicted membrane proteins" Osteogenesis "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 78.7" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 728.7;Neutrophils: 358.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047251 Approved Approved "Nucleoli fibrillar center,Cytosol" NA NA 57000 "Cluster 32: Basophils - Transcription" "Cluster 40: Non-specific - Mixed function" "Cluster 55: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 3 "Nucleoli fibrillar center, Cytosol" "HPA047251: " "unprognostic (4.06e-1)" "unprognostic (1.35e-2)" "unprognostic (4.20e-3)" "unprognostic (1.05e-1)" "unprognostic (2.53e-1)" "unprognostic (2.40e-1)" "unprognostic (8.64e-2)" "unprognostic (2.96e-2)" "unprognostic (2.95e-3)" "unprognostic (1.41e-2)" "unprognostic (9.98e-2)" "potential prognostic unfavorable (6.46e-5)" "unprognostic (1.12e-3)" "unprognostic (3.48e-2)" "unprognostic (1.36e-2)" "unprognostic (5.40e-2)" "unprognostic (3.69e-1)" "unprognostic (1.94e-1)" "unprognostic (3.66e-1)" "unprognostic (1.30e-2)" "unprognostic (2.97e-2)" "unprognostic (5.02e-2)" "unprognostic (1.11e-1)" "unprognostic (6.78e-3)" "unprognostic (2.74e-2)" "unprognostic (1.03e-1)" "unprognostic (1.29e-1)" "unprognostic (2.40e-3)" "unprognostic (1.28e-1)" SUDS3 "FLJ00052, SAP45, SDS3" ENSG00000111707 "SDS3 homolog, SIN3A corepressor complex component" Q9H7L9 12 118376555-118418033 "Essential proteins, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 269.0;Oocytes: 327.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040402, HPA041972" Approved Supported "Nuclear bodies,Cytosol" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 38: Non-specific - Transcription" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 52 "Nuclear bodies, Cytosol" "HPA040402: , HPA041972: " "unprognostic (1.92e-1)" "unprognostic (5.15e-2)" "unprognostic (5.81e-2)" "unprognostic (1.84e-2)" "unprognostic (1.26e-1)" "unprognostic (1.19e-1)" "unprognostic (1.00e-1)" "unprognostic (4.42e-3)" "unprognostic (3.21e-1)" "potential prognostic unfavorable (2.34e-4)" "unprognostic (1.88e-2)" "unprognostic (1.30e-1)" "unprognostic (1.33e-1)" "unprognostic (5.60e-3)" "unprognostic (1.60e-3)" "unprognostic (4.83e-2)" "unprognostic (6.85e-2)" "unprognostic (7.38e-2)" "unprognostic (4.81e-2)" "unprognostic (4.92e-2)" "potential prognostic unfavorable (3.25e-4)" "unprognostic (1.67e-2)" "unprognostic (2.56e-2)" "unprognostic (1.54e-1)" "unprognostic (1.55e-1)" "unprognostic (4.28e-1)" "unprognostic (5.52e-2)" "unprognostic (1.45e-2)" "unprognostic (2.19e-1)" "unprognostic (5.73e-2)" "unprognostic (2.80e-1)" SUFU "PRO1280, SUFUH, SUFUXL" ENSG00000107882 "SUFU negative regulator of hedgehog signaling" Q9UMX1 10 102503972-102633535 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein" "Cancer-related genes, Ciliopathy, Disease variant, Joubert syndrome, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 259.2;Late spermatids: 178.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008700 Supported Supported "Nucleoplasm,Primary cilium" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 24: Non-specific - Transcription" "Cluster 54: Immune cells - T cell receptor" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 72 Nucleoplasm "Primary cilium" "HPA008700: " "unprognostic (2.19e-2)" "unprognostic (4.00e-2)" "unprognostic (4.00e-2)" "unprognostic (4.36e-2)" "unprognostic (3.33e-1)" "unprognostic (1.90e-1)" "unprognostic (3.94e-1)" "unprognostic (1.37e-2)" "unprognostic (1.94e-2)" "unprognostic (1.52e-1)" "potential prognostic favorable (2.78e-5)" "unprognostic (3.07e-2)" "unprognostic (8.83e-2)" "unprognostic (2.78e-2)" "unprognostic (1.49e-1)" "unprognostic (1.69e-1)" "unprognostic (5.19e-2)" "unprognostic (6.94e-2)" "unprognostic (9.36e-2)" "unprognostic (1.15e-2)" "potential prognostic unfavorable (1.49e-4)" "unprognostic (9.48e-2)" "potential prognostic unfavorable (7.42e-4)" "unprognostic (3.63e-1)" "unprognostic (1.34e-1)" "unprognostic (1.18e-1)" "unprognostic (2.93e-1)" "unprognostic (2.49e-1)" "unprognostic (6.16e-2)" "unprognostic (9.71e-2)" "unprognostic (2.93e-1)" SUGCT "C7orf10, DERP13, FLJ11808, ORF19" ENSG00000175600 "Succinyl-CoA:glutarate-CoA transferase" Q9HAC7 7 40135005-40860763 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant, Glutaricaciduria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 41.4;liver: 26.6" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 269.7;Choroid plexus epithelial cells: 249.3;Ependymal cells: 246.3;Myonuclei: 260.7;Proximal tubule cells: 910.5" "Cell type enhanced" "Detected in all" "ependymal cell: 260.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD4 T-cell: 1.4" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026698, HPA026704, HPA026705" Enhanced Approved "Microtubules,Mitotic spindle,Primary cilium,Basal body" Yes NA "Cluster 76: Non-specific - Metabolism" "Cluster 3: Choroid plexus - Cilium" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 88: Proximal tubular cells - Transmembrane transport" "Microtubules, Primary cilium" "Mitotic spindle, Basal body" "HPA026698: , HPA026704: , HPA026705: " "unprognostic (7.79e-2)" "unprognostic (1.12e-1)" "unprognostic (2.97e-2)" "unprognostic (2.96e-1)" "unprognostic (2.71e-1)" "unprognostic (1.30e-1)" "unprognostic (2.93e-3)" "unprognostic (6.49e-2)" "validated prognostic favorable (5.65e-13)" "validated prognostic favorable (4.29e-4)" "unprognostic (1.74e-2)" "potential prognostic favorable (3.25e-4)" "unprognostic (2.86e-3)" "potential prognostic unfavorable (5.78e-4)" "unprognostic (9.58e-2)" "unprognostic (1.68e-2)" "unprognostic (7.68e-2)" "unprognostic (1.22e-3)" "unprognostic (4.58e-3)" "unprognostic (9.97e-2)" "unprognostic (2.57e-1)" "unprognostic (3.34e-1)" "unprognostic (4.06e-2)" "unprognostic (5.32e-1)" "unprognostic (2.34e-3)" "unprognostic (1.81e-1)" "potential prognostic unfavorable (2.66e-5)" "unprognostic (1.26e-2)" SUGP1 "DKFZp434E2216, F23858, RBP, SF4" ENSG00000105705 "SURP and G-patch domain containing 1" Q8IWZ8 19 19276018-19320509 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 174.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004890 Approved Approved Nucleoplasm NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 67: Testis - Mixed function" "Cluster 14: Neurons - Synaptic function" "Cluster 23: Non-specific - Transcription" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 37 Nucleoplasm "HPA004890: " "unprognostic (4.54e-3)" "unprognostic (5.32e-2)" "unprognostic (1.21e-1)" "unprognostic (1.44e-1)" "unprognostic (2.05e-1)" "unprognostic (3.72e-1)" "unprognostic (7.07e-2)" "unprognostic (2.92e-2)" "unprognostic (2.48e-1)" "potential prognostic favorable (4.23e-7)" "unprognostic (7.25e-2)" "unprognostic (7.62e-2)" "unprognostic (1.48e-1)" "unprognostic (3.44e-2)" "unprognostic (3.25e-1)" "unprognostic (4.07e-2)" "unprognostic (4.13e-1)" "unprognostic (3.82e-1)" "unprognostic (1.99e-1)" "unprognostic (4.39e-3)" "unprognostic (2.56e-1)" "unprognostic (4.45e-2)" "unprognostic (4.57e-1)" "unprognostic (1.30e-1)" "unprognostic (5.78e-2)" "unprognostic (1.48e-1)" "unprognostic (5.76e-2)" "unprognostic (1.91e-1)" "unprognostic (1.31e-1)" "unprognostic (3.05e-1)" SUGP2 "KIAA0365, SFRS14" ENSG00000064607 "SURP and G-patch domain containing 2" Q8IX01 19 18990888-19034023 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041557, HPA061111" Enhanced Enhanced "Nucleoplasm,Nuclear bodies" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 67: Testis - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 3: Early primary spermatocytes - Early meiosis" 12 Nucleoplasm "Nuclear bodies" "HPA041557: , HPA061111: " "unprognostic (1.21e-1)" "unprognostic (9.33e-2)" "unprognostic (4.54e-2)" "unprognostic (4.13e-1)" "unprognostic (1.80e-1)" "unprognostic (6.75e-2)" "unprognostic (1.03e-3)" "unprognostic (5.62e-2)" "unprognostic (2.26e-3)" "unprognostic (6.32e-2)" "unprognostic (2.59e-1)" "unprognostic (5.54e-2)" "unprognostic (1.54e-3)" "unprognostic (8.90e-2)" "unprognostic (1.00e-1)" "unprognostic (1.05e-1)" "unprognostic (1.42e-1)" "unprognostic (3.09e-2)" "unprognostic (3.16e-1)" "unprognostic (2.70e-1)" "unprognostic (2.85e-3)" "unprognostic (1.30e-3)" "unprognostic (5.70e-2)" "unprognostic (2.60e-3)" "potential prognostic favorable (3.99e-7)" "unprognostic (3.34e-2)" "unprognostic (1.20e-2)" "unprognostic (2.48e-1)" "unprognostic (6.48e-2)" "unprognostic (2.83e-2)" SUGT1 SGT1 ENSG00000165416 "SGT1 homolog, MIS12 kinetochore complex assembly cochaperone" Q9Y2Z0 13 52652709-52700909 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 350.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015942, HPA043949, HPA069215" Uncertain Supported "Nuclear bodies,Cytosol,Acrosome,Flagellar centriole,Mid piece,Principal piece,End piece" NA NA 13000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 19: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 59 "Nuclear bodies, Cytosol" "Acrosome, Flagellar centriole, Mid piece, Principal piece, End piece" "CAB015942: , HPA043949: , HPA069215: " "unprognostic (3.77e-3)" "unprognostic (2.40e-2)" "unprognostic (2.21e-1)" "unprognostic (2.49e-2)" "unprognostic (3.11e-1)" "unprognostic (2.82e-1)" "unprognostic (2.58e-1)" "unprognostic (9.96e-2)" "potential prognostic unfavorable (1.89e-4)" "unprognostic (2.15e-2)" "potential prognostic favorable (6.91e-7)" "unprognostic (3.11e-2)" "unprognostic (1.42e-1)" "unprognostic (3.31e-2)" "unprognostic (1.91e-3)" "unprognostic (1.77e-3)" "potential prognostic unfavorable (2.85e-8)" "unprognostic (8.13e-2)" "unprognostic (3.38e-2)" "unprognostic (5.87e-3)" "potential prognostic unfavorable (2.98e-4)" "unprognostic (1.27e-1)" "potential prognostic unfavorable (2.13e-4)" "unprognostic (1.77e-1)" "unprognostic (4.36e-1)" "unprognostic (3.80e-1)" "unprognostic (3.30e-1)" "unprognostic (6.23e-2)" "unprognostic (1.64e-1)" "unprognostic (2.84e-1)" "unprognostic (1.24e-1)" SULF1 "hSulf-1, KIAA1077, SULF-1" ENSG00000137573 "Sulfatase 1" Q8IWU6 8 69466624-69660915 "Predicted intracellular proteins, Predicted secreted proteins" Apoptosis Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 112.2" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 1184.5;Early spermatids: 323.6;Epicardial cells: 338.8;Fibro-adipogenic progenitors: 202.4;Mesothelial cells: 697.0;Müller glia: 562.1;Podocytes: 574.0;Retinal pigment epithelial cells: 669.3" "Group enriched" "Detected in many" 5 "choroid plexus epithelial cell: 1156.8;deep-layer corticothalamic and 6b: 317.5" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 9 "choroid plexus: 387.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 43.8;thyroid cancer: 65.3" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Heart muscle - Fibroblasts, Spleen - Smooth muscle cells, Stomach - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054728 Supported "Secreted in other tissues" Enzyme NA NA 14000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 1 "HPA054728: " "unprognostic (1.23e-2)" "unprognostic (5.43e-2)" "unprognostic (4.79e-2)" "unprognostic (6.52e-3)" "unprognostic (3.64e-2)" "unprognostic (3.35e-1)" "unprognostic (4.98e-3)" "unprognostic (2.45e-3)" "unprognostic (7.39e-2)" "unprognostic (1.70e-1)" "unprognostic (1.24e-2)" "unprognostic (2.18e-2)" "potential prognostic unfavorable (3.87e-5)" "unprognostic (1.42e-2)" "unprognostic (2.57e-1)" "unprognostic (1.31e-2)" "unprognostic (1.50e-3)" "unprognostic (1.44e-1)" "unprognostic (2.94e-1)" "unprognostic (2.13e-2)" "unprognostic (2.30e-3)" "unprognostic (5.34e-2)" "unprognostic (2.16e-1)" "unprognostic (2.90e-1)" "unprognostic (1.07e-1)" "unprognostic (9.95e-3)" "unprognostic (1.48e-1)" "unprognostic (1.13e-2)" "unprognostic (5.79e-2)" "unprognostic (5.47e-2)" "unprognostic (1.81e-1)" SULF2 "HSULF-2, KIAA1247, SULF-2" ENSG00000196562 "Sulfatase 2" Q8IWU5 20 47656197-47786616 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 147.8" "Cell type enhanced" "Detected in many" "cDC: 316.4;Decidual stromal cells: 285.7;Endometrial stromal cells: 355.1;Granulosa cells: 250.6;monocytes: 255.2;Neutrophils: 320.6;Oligodendrocyte progenitor cells: 362.3;pDCs: 511.1;Podocytes: 423.3" "Cell type enhanced" "Detected in all" "oligodendrocyte precursor cell: 399.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "basophil: 22.2;classical monocyte: 17.3;intermediate monocyte: 15.7;myeloid DC: 19.5;neutrophil: 26.4;non-classical monocyte: 8.7;plasmacytoid DC: 25.6" "Group enriched" "Detected in many" 78 "dendritic cells: 25.6;granulocytes: 26.4;monocytes: 17.3" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Heart muscle - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002325 Approved "Secreted in other tissues" Enzyme NA NA 1700000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 75: Ovary - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 2 "HPA002325: " "unprognostic (2.74e-1)" "unprognostic (7.45e-2)" "unprognostic (3.61e-2)" "potential prognostic unfavorable (4.86e-4)" "unprognostic (2.12e-1)" "unprognostic (5.71e-2)" "unprognostic (4.69e-1)" "unprognostic (1.24e-2)" "unprognostic (1.56e-1)" "unprognostic (1.52e-1)" "potential prognostic unfavorable (8.44e-5)" "unprognostic (6.54e-3)" "unprognostic (1.68e-1)" "unprognostic (2.69e-1)" "unprognostic (1.24e-2)" "unprognostic (6.02e-2)" "unprognostic (1.50e-2)" "unprognostic (5.71e-2)" "unprognostic (1.37e-1)" "unprognostic (3.57e-2)" "unprognostic (4.12e-2)" "unprognostic (1.52e-3)" "unprognostic (1.19e-2)" "unprognostic (8.22e-2)" "unprognostic (1.32e-2)" "potential prognostic favorable (3.70e-4)" "unprognostic (1.45e-2)" "unprognostic (3.63e-2)" "unprognostic (4.82e-2)" "unprognostic (9.00e-2)" "unprognostic (7.32e-2)" SULT1A1 "P-PST, STP, STP1" ENSG00000196502 "Sulfotransferase family 1A member 1" P50225 16 28605196-28614279 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Catecholamine metabolism, Lipid metabolism, Steroid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 105.1;liver: 191.2" "Cell type enhanced" "Detected in some" "Astrocytes: 42.5;Bergmann glia: 24.1;Brain excitatory neurons: 64.5;Brain inhibitory neurons: 59.3;Choroid plexus epithelial cells: 46.6;Distal convoluted tubule cells: 40.3;Enterocytes: 17.4;Ependymal cells: 25.4;Loop of henle epithelial cells: 30.5;Oligodendrocyte progenitor cells: 46.5;Other brain neurons: 50.0;Podocytes: 51.6;Renal connecting tubule cells: 23.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 118.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 245.3;intermediate monocyte: 201.2;myeloid DC: 112.3;neutrophil: 227.1;non-classical monocyte: 114.4" "Group enriched" "Detected in all" 24 "dendritic cells: 112.3;granulocytes: 227.1;monocytes: 245.3" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "HPA049500, HPA051051" Supported NA NA 360000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 77: Intestine - Digestion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 35: Neurons - Synaptic function & neurogenesis" 6 "HPA049500: , HPA051051: " "unprognostic (1.41e-2)" "unprognostic (2.46e-2)" "unprognostic (8.40e-2)" "unprognostic (1.38e-3)" "unprognostic (1.39e-2)" "unprognostic (2.11e-3)" "unprognostic (1.13e-2)" "unprognostic (1.62e-2)" "unprognostic (2.41e-2)" "unprognostic (1.40e-1)" "unprognostic (4.98e-2)" "unprognostic (2.15e-1)" "unprognostic (6.21e-3)" "unprognostic (4.16e-3)" "unprognostic (3.66e-3)" "potential prognostic favorable (2.96e-4)" "unprognostic (1.60e-2)" "unprognostic (3.29e-1)" "unprognostic (2.42e-1)" "unprognostic (5.70e-2)" "unprognostic (2.54e-2)" "unprognostic (4.29e-2)" "unprognostic (3.25e-2)" "unprognostic (7.94e-2)" "unprognostic (3.31e-1)" "unprognostic (1.64e-3)" "unprognostic (1.74e-1)" "unprognostic (6.56e-2)" "unprognostic (9.81e-3)" "unprognostic (1.21e-1)" "unprognostic (2.59e-1)" SULT1A2 "HAST4, STP2" ENSG00000197165 "Sulfotransferase family 1A member 2" P50226 16 28591943-28597050 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Catecholamine metabolism, Lipid metabolism, Steroid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "intestine: 49.1;liver: 47.6" "Cell type enriched" "Detected in some" 4 "Enterocytes: 240.2" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 22.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 11.2;intermediate monocyte: 8.7;myeloid DC: 4.1;neutrophil: 15.4;non-classical monocyte: 4.7" "Group enriched" "Detected in many" 15 "dendritic cells: 4.1;granulocytes: 15.4;monocytes: 11.2" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes" "HPA049500, HPA051051" Supported NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 77: Intestine - Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 3 "HPA049500: , HPA051051: " "unprognostic (1.21e-2)" "unprognostic (6.69e-3)" "unprognostic (8.60e-2)" "unprognostic (2.51e-1)" "unprognostic (8.32e-3)" "unprognostic (8.66e-3)" "unprognostic (1.56e-1)" "unprognostic (1.08e-3)" "unprognostic (4.26e-2)" "unprognostic (1.58e-1)" "unprognostic (6.25e-2)" "unprognostic (5.35e-2)" "unprognostic (1.31e-2)" "unprognostic (1.45e-2)" "unprognostic (7.95e-2)" "unprognostic (1.79e-1)" "unprognostic (4.90e-3)" "unprognostic (1.70e-1)" "unprognostic (1.31e-1)" "unprognostic (2.11e-2)" "unprognostic (2.18e-1)" "unprognostic (1.19e-2)" "unprognostic (1.07e-1)" "unprognostic (3.64e-2)" "unprognostic (1.31e-1)" "unprognostic (3.14e-2)" SULT1A3 "STM, TL-PST" ENSG00000261052 "Sulfotransferase family 1A member 3" P0DMM9 16 30199228-30204310 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Catecholamine metabolism, Lipid metabolism, Steroid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "intestine: 225.7" "Cell type enhanced" "Detected in some" "Astrocytes: 6.5;Bergmann glia: 3.3;Brain excitatory neurons: 3.7;Brain inhibitory neurons: 3.3;Choroid plexus epithelial cells: 3.8;Distal convoluted tubule cells: 1.2;Ependymal cells: 1.6;Microglia: 3.3;Oligodendrocyte progenitor cells: 2.5;Oligodendrocytes: 4.0;Other brain neurons: 2.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "classical monocyte: 64.6;intermediate monocyte: 55.7;myeloid DC: 35.2;non-classical monocyte: 26.8" "Group enriched" "Detected in all" 11 "dendritic cells: 35.2;monocytes: 64.6" "Low cancer specificity" "Detected in all" "HPA049500, HPA051051" Supported NA NA 270000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 22: Non-specific - Basic cellular functions" "HPA049500: , HPA051051: " "unprognostic (9.45e-3)" "unprognostic (1.29e-2)" "unprognostic (1.11e-2)" "potential prognostic favorable (1.13e-4)" "unprognostic (1.36e-1)" "unprognostic (5.08e-2)" "unprognostic (1.92e-1)" "unprognostic (4.50e-2)" "unprognostic (1.77e-2)" "potential prognostic unfavorable (2.73e-4)" "unprognostic (1.44e-1)" "unprognostic (4.31e-2)" "unprognostic (3.19e-3)" "unprognostic (1.33e-1)" "unprognostic (6.43e-2)" "unprognostic (6.66e-2)" "unprognostic (1.34e-2)" "unprognostic (2.61e-1)" "unprognostic (1.58e-2)" "potential prognostic unfavorable (6.21e-4)" "unprognostic (1.91e-2)" "unprognostic (4.22e-2)" "unprognostic (1.70e-1)" "unprognostic (1.19e-1)" "unprognostic (1.11e-1)" "unprognostic (3.64e-1)" "unprognostic (3.75e-1)" "unprognostic (2.86e-1)" "unprognostic (5.15e-2)" SULT1A4 ENSG00000213648 "Sulfotransferase family 1A member 4" P0DMN0 16 29459913-29464966 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Catecholamine metabolism, Lipid metabolism, Steroid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 27.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 24.5;myeloid DC: 17.8" "Group enriched" "Detected in many" 11 "dendritic cells: 17.8;monocytes: 24.5" "Low cancer specificity" "Detected in many" "HPA049500, HPA051051" Supported NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 77: Intestine - Digestion" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 7: Liver cancer - Metabolism" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 3 "HPA049500: , HPA051051: " "unprognostic (4.15e-2)" "unprognostic (1.30e-1)" "unprognostic (2.13e-3)" "unprognostic (1.83e-1)" "unprognostic (6.08e-3)" "unprognostic (2.38e-2)" "unprognostic (2.49e-1)" "unprognostic (2.49e-1)" "unprognostic (2.46e-2)" "unprognostic (6.48e-2)" "unprognostic (2.02e-1)" "unprognostic (9.84e-2)" "unprognostic (3.70e-1)" "unprognostic (3.54e-2)" "unprognostic (9.77e-3)" "unprognostic (6.65e-2)" "unprognostic (8.03e-3)" "unprognostic (2.34e-2)" "unprognostic (1.72e-1)" "unprognostic (1.12e-1)" "unprognostic (6.61e-2)" "unprognostic (1.40e-2)" "unprognostic (1.26e-1)" "unprognostic (1.32e-2)" "unprognostic (1.69e-1)" "unprognostic (4.21e-1)" "unprognostic (1.82e-1)" SULT1B1 ST1B2 ENSG00000173597 "Sulfotransferase family 1B member 1" O43704 4 69721167-69787961 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 93.3;stomach 1: 42.1" "Cell type enhanced" "Detected in some" "Colonocytes: 285.1;Enteric transient amplifying cells: 93.8;Enterocytes: 257.5;Foveolar cells: 162.6;Hepatocytes: 61.9;Monocyte progenitors: 65.6;Neutrophil progenitors: 90.1;Neutrophils: 508.8;Parietal cells: 113.1" "Cell type enriched" "Detected in some" 5 "endothelial cell: 48.7" "Group enriched" "Detected in many" 5 "Colon Adenocarcinoma (TCGA): 16.4;Liver Hepatocellular Carcinoma (TCGA): 5.0;Pancreatic Adenocarcinoma (TCGA): 11.7;Rectum Adenocarcinoma (TCGA): 14.7;Stomach Adenocarcinoma (TCGA): 12.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 10.6;neutrophil: 32.2" "Lineage enriched" "Detected in many" 6 "granulocytes: 32.2" "Low cancer specificity" "Detected in many" "Adipose visceral - Neutrophils, Colon - Colon enterocytes, Liver - Hepatocytes, Prostate - Macrophages, Skin - Macrophages, Spleen - Neutrophils_2, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA002107 Enhanced Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 9: Non-specific - Receptor signaling" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 7 "Golgi apparatus" Nucleoplasm "HPA002107: " "unprognostic (1.17e-3)" "unprognostic (8.75e-3)" "unprognostic (1.82e-1)" "potential prognostic favorable (3.72e-4)" "unprognostic (3.27e-2)" "unprognostic (2.50e-1)" "unprognostic (3.72e-2)" "unprognostic (9.94e-3)" "unprognostic (4.31e-2)" "unprognostic (2.67e-3)" "unprognostic (3.44e-1)" "unprognostic (5.10e-2)" "potential prognostic favorable (9.70e-4)" "unprognostic (1.22e-2)" "unprognostic (1.31e-1)" "unprognostic (1.44e-1)" "unprognostic (6.30e-3)" "unprognostic (9.92e-2)" "unprognostic (2.76e-2)" "potential prognostic favorable (7.91e-4)" "unprognostic (8.25e-2)" "unprognostic (1.24e-1)" "potential prognostic unfavorable (1.38e-4)" "unprognostic (4.02e-1)" "unprognostic (1.28e-1)" "unprognostic (9.22e-3)" "unprognostic (2.39e-2)" SULT1C2 "ST1C1, SULT1C1" ENSG00000198203 "Sulfotransferase family 1C member 2" O00338 2 108288639-108309915 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "kidney: 69.6;stomach 1: 154.3" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 334.9;Foveolar cells: 934.3;Loop of henle epithelial cells: 193.1;Mucous neck cells: 125.9;Proximal tubule cells: 241.1;Renal collecting duct intercalated cells: 260.9;Renal connecting tubule cells: 287.9" "Group enriched" "Detected in some" 5 "choroid plexus epithelial cell: 56.4;endothelial cell: 14.9;fibroblast: 14.8" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 117.3" "Region enriched" "Detected in many" 6 "choroid plexus: 16.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 49.6;liver cancer: 20.1" "Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA007190 Approved NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 68: Foveolar cells - Mucosal defense" 3 "HPA007190: " "unprognostic (4.16e-2)" "unprognostic (1.08e-2)" "unprognostic (1.13e-1)" "unprognostic (8.32e-2)" "unprognostic (3.05e-1)" "unprognostic (2.29e-2)" "unprognostic (8.72e-2)" "unprognostic (2.17e-1)" "potential prognostic unfavorable (2.23e-4)" "unprognostic (1.35e-2)" "potential prognostic favorable (4.03e-4)" "unprognostic (2.22e-2)" "unprognostic (3.54e-2)" "unprognostic (6.48e-2)" "unprognostic (8.91e-2)" "unprognostic (4.02e-1)" "unprognostic (7.77e-2)" "unprognostic (9.64e-3)" "unprognostic (7.49e-2)" "unprognostic (1.40e-1)" "unprognostic (1.31e-1)" "unprognostic (1.89e-1)" "unprognostic (9.78e-2)" "unprognostic (8.83e-3)" "unprognostic (3.48e-1)" SULT1C3 ENSG00000196228 "Sulfotransferase family 1C member 3" Q6IMI6 2 108239968-108265351 "Enzymes, Predicted intracellular proteins" "Lipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 33 "breast: 266.7" "Cell type enhanced" "Detected in some" "Adipocytes: 13.0;Enterocytes: 17.6;Esophageal apical cells: 2.7;Foveolar cells: 3.7;Gastric chief cells: 2.2;Goblet cells: 6.1;Loop of henle epithelial cells: 5.2;Respiratory ionocytes: 2.5" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Breast Invasive Carcinoma (TCGA): 6.2" "Region enhanced" "Detected in single" "choroid plexus: 3.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 1.6;Gastric cancer: 3.3" "Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA060368 Approved Cytosol NA NA "Cluster 55: Breast - Lactation" "Cluster 3: Choroid plexus - Cilium" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 1: Enterocytes - Absorption and Digestion" 1 Cytosol "HPA060368: " "unprognostic (3.60e-2)" "unprognostic (7.44e-2)" "unprognostic (3.39e-2)" "unprognostic (5.34e-3)" SULT1C4 "SULT1C, SULT1C2" ENSG00000198075 "Sulfotransferase family 1C member 4" O75897 2 108377911-108388989 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bergmann glia: 27.6;Cholangiocytes: 69.1;Ependymal cells: 56.2;Epididymal efferent duct ciliated cells: 81.4;Fallopian tube ciliated cells: 39.5;Granulosa cells: 34.1;Hematopoietic stem cells: 40.8;Lymphatic endothelial cells: 31.5;Medullary thymic epithelial cells: 31.2;Müller glia: 34.6;Ovarian stromal cells: 48.1;Pituitary stem cells: 27.5;Proximal tubule cells: 63.0;Vascular endothelial cells: 29.4" "Cell type enhanced" "Detected in many" "endothelial cell: 58.3;ependymal cell: 69.7" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 144.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Kidney cancer: 7.6;liver cancer: 21.8;Neuroblastoma: 14.0;testis cancer: 10.7" "Colon - Enteric glia cells, Prostate - Fibroblasts, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "Region enhanced" "Detected in all" "spinal cord: 51.1" HPA034530 Approved Cytosol NA NA "Cluster 65: Brain - Transcription" "Cluster 46: Brainstem - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 94: Gonadal somatic cells - Mixed function" 60 Cytosol "HPA034530: " "unprognostic (1.69e-1)" "unprognostic (1.96e-1)" "unprognostic (2.26e-1)" "unprognostic (3.34e-2)" "unprognostic (3.12e-2)" "unprognostic (2.32e-1)" "unprognostic (7.52e-2)" "unprognostic (9.94e-2)" "unprognostic (9.69e-2)" "potential prognostic favorable (1.37e-7)" "unprognostic (3.14e-3)" "potential prognostic favorable (4.76e-4)" "unprognostic (2.70e-2)" "unprognostic (2.18e-1)" "unprognostic (6.45e-2)" "unprognostic (7.16e-2)" "unprognostic (1.27e-2)" "unprognostic (1.86e-1)" "unprognostic (1.16e-1)" "unprognostic (1.18e-2)" "unprognostic (1.25e-1)" "unprognostic (1.74e-1)" "unprognostic (1.65e-2)" "unprognostic (7.78e-2)" "unprognostic (4.35e-2)" "unprognostic (1.31e-2)" "unprognostic (4.65e-2)" "unprognostic (1.72e-2)" "unprognostic (6.37e-2)" SULT1E1 "EST, STE" ENSG00000109193 "Sulfotransferase family 1E member 1" P49888 4 69841212-69860145 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 25.8;liver: 34.7;skin 1: 18.4;vagina: 29.0" "Cell type enhanced" "Detected in some" "Conjunctival goblet cells: 139.8;Endometrial ciliated cells: 100.8;Endometrial luminal cells: 44.6;Enteric transient amplifying cells: 21.8;Enterocytes: 48.6;Foveolar cells: 15.5;Hepatocytes: 16.0;Respiratory basal cells: 51.3;Salivary basal cells: 25.4" "Cell type enriched" "Detected in some" 7 "fibroblast: 11.3" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 9 "choroid plexus: 9.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 4.4" "Liver - Hepatocytes, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA028213, HPA028728, CAB047344" Enhanced Uncertain "Nuclear membrane,Cytosol" NA NA "Cluster 77: Intestine - Digestion" "Cluster 36: Choroid plexus - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 1 "Nuclear membrane, Cytosol" "CAB047344: , HPA028213: , HPA028728: " "unprognostic (1.34e-2)" "unprognostic (5.24e-1)" "unprognostic (6.54e-3)" "unprognostic (1.30e-1)" "unprognostic (4.36e-2)" "unprognostic (1.17e-1)" "unprognostic (9.09e-2)" "unprognostic (3.94e-2)" "unprognostic (1.73e-1)" "unprognostic (5.30e-2)" "unprognostic (2.11e-3)" "unprognostic (1.78e-1)" "unprognostic (1.20e-1)" "unprognostic (6.32e-2)" "unprognostic (4.12e-1)" "unprognostic (1.49e-1)" SULT2A1 "DHEA-ST, STD" ENSG00000105398 "Sulfotransferase family 2A member 1" Q06520 19 47870467-47886315 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Bile acid catabolism, Lipid degradation, Lipid metabolism, Steroid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "liver: 1005.4" "Cell type enriched" "Detected in some" 8 "Hepatocytes: 2000.0" "Low cell type specificity" "Detected in some" "Cancer enriched" "Detected in some" 36 "Liver Hepatocellular Carcinoma (TCGA): 316.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.4" "Lineage enriched" "Detected in single" 5 "granulocytes: 2.4" "Cancer enriched" "Detected in single" 8 "liver cancer: 7.7" "Adrenal gland - Adrenal cortex cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB018755, HPA041487, HPA063633" Enhanced Supported Cytosol NA NA 760000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 48: Non-specific - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 93: Hepatocytes - Bile production & excretion" 5 Cytosol "CAB018755: , HPA041487: , HPA063633: " "unprognostic (1.88e-2)" "unprognostic (7.27e-2)" "unprognostic (5.62e-2)" "unprognostic (6.47e-3)" "unprognostic (1.69e-3)" "unprognostic (2.91e-1)" "unprognostic (8.92e-2)" "unprognostic (1.68e-1)" "unprognostic (3.45e-2)" "unprognostic (1.65e-2)" SULT2B1 HSST2 ENSG00000088002 "Sulfotransferase family 2B member 1" O00204 19 48552172-48599425 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" Transferase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 105.9;esophagus: 305.3;skin 1: 195.8;vagina: 152.9" "Group enriched" "Detected in many" 4 "Esophageal apical cells: 3869.3;Esophageal suprabasal cells: 1084.6" "Cell type enhanced" "Detected in many" "leukocyte: 6.7" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 90.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Breast - Breast glandular cells, Lung - Alveolar cells type 1, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA041724, HPA043539, HPA076510" Enhanced Enhanced Vesicles,Cytosol NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 85: Squamous epithelial cells - Keratinization" 11 Vesicles Cytosol "HPA041724: , HPA043539: , HPA076510: " "unprognostic (3.19e-1)" "unprognostic (1.56e-2)" "unprognostic (2.13e-1)" "unprognostic (9.55e-2)" "unprognostic (9.46e-3)" "unprognostic (3.99e-2)" "unprognostic (1.03e-1)" "unprognostic (9.06e-2)" "unprognostic (1.91e-1)" "unprognostic (1.48e-2)" "unprognostic (5.64e-2)" "unprognostic (2.28e-2)" "unprognostic (6.49e-3)" "potential prognostic unfavorable (1.69e-4)" "unprognostic (6.87e-2)" "unprognostic (9.68e-2)" "unprognostic (1.44e-1)" "unprognostic (4.68e-3)" "unprognostic (4.38e-2)" "unprognostic (1.13e-2)" "potential prognostic unfavorable (6.87e-4)" "unprognostic (6.28e-2)" "unprognostic (2.45e-1)" "unprognostic (1.32e-1)" "unprognostic (3.06e-1)" "unprognostic (1.79e-3)" "unprognostic (1.08e-1)" "unprognostic (1.03e-1)" "unprognostic (1.99e-2)" SULT4A1 "hBR-STL-1, SULTX3" ENSG00000130540 "Sulfotransferase family 4A member 1" Q9BR01 22 43824509-43862513 "Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 37 "brain: 96.3" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 21.3;Brain excitatory neurons: 62.7;Brain inhibitory neurons: 61.5;Early spermatids: 32.8;Lactotrophs: 22.1;Late spermatids: 47.9;Other brain neurons: 65.1;Retinal amacrine cells: 60.4;Retinal pigment epithelial cells: 63.9" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in single" 10 "Glioblastoma Multiforme (TCGA): 3.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 17 "Neuroblastoma: 6.4" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Skin - Sebaceous gland cells, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003129 Enhanced NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 98: Neurons - Neurotransmission & signaling" 8 "HPA003129: " "unprognostic (1.31e-1)" "unprognostic (6.10e-3)" "unprognostic (1.08e-1)" "unprognostic (8.69e-2)" "unprognostic (7.02e-2)" SULT6B1 ENSG00000138068 "Sulfotransferase family 6B member 1" Q6IMI4 2 37167820-37196598 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 5 "testis: 1.8" "Cell type enriched" "Detected in some" 4 "Late primary spermatocytes: 41.0" "Low cell type specificity" "Detected in single" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 12 "basophil: 1.6" "Lineage enriched" "Detected in single" 17 "granulocytes: 1.6" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 53: Neurons - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" SUMF1 "FGE, UNQ3037" ENSG00000144455 "Sulfatase modifying factor 1" Q8NBK3 3 3700814-4467273 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant, Ichthyosis, Leukodystrophy, Metachromatic leukodystrophy, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gonadotrophs: 656.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038025 Uncertain "Intracellular and membrane" Enzyme NA NA 180000 "Cluster 29: Non-specific - Unknown function" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Transcription" 3 "HPA038025: " "unprognostic (5.66e-2)" "unprognostic (2.78e-2)" "unprognostic (1.86e-1)" "unprognostic (4.88e-2)" "unprognostic (9.20e-2)" "unprognostic (2.71e-2)" "unprognostic (1.63e-2)" "unprognostic (2.49e-1)" "unprognostic (1.58e-1)" "unprognostic (6.07e-2)" "potential prognostic favorable (1.58e-5)" "unprognostic (6.74e-2)" "unprognostic (2.33e-2)" "unprognostic (1.46e-3)" "unprognostic (1.40e-2)" "unprognostic (2.06e-1)" "unprognostic (9.41e-2)" "unprognostic (1.41e-2)" "unprognostic (1.09e-1)" "unprognostic (2.65e-1)" "potential prognostic unfavorable (4.97e-4)" "unprognostic (2.23e-2)" "unprognostic (2.52e-1)" "unprognostic (4.72e-2)" "unprognostic (5.05e-2)" "unprognostic (9.95e-2)" "unprognostic (4.94e-2)" "unprognostic (6.06e-2)" "unprognostic (2.97e-1)" "unprognostic (1.31e-1)" "unprognostic (1.18e-2)" SUMF2 DKFZp566I1024 ENSG00000129103 "Sulfatase modifying factor 2" Q8NBJ7 7 56064002-56080670 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024040, CAB025743, HPA074892" Enhanced Uncertain "Vesicles,Plasma membrane" "Intracellular and membrane" "No annotated function" Yes No 370000 "Cluster 13: Non-specific - Mitochondria" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 21: Non-specific - Metabolism" "Cluster 67: Non-specific - Unknown function" "Cluster 51: Secretory epithelial cells - Mixed function" 13 "Vesicles, Plasma membrane" "CAB025743: , HPA024040: , HPA074892: " "unprognostic (2.40e-3)" "unprognostic (1.38e-1)" "unprognostic (9.82e-2)" "unprognostic (1.13e-3)" "unprognostic (3.25e-2)" "unprognostic (3.89e-2)" "unprognostic (9.68e-3)" "unprognostic (7.51e-3)" "unprognostic (9.08e-2)" "unprognostic (1.08e-1)" "potential prognostic favorable (5.63e-6)" "unprognostic (3.65e-1)" "unprognostic (1.71e-1)" "unprognostic (9.37e-3)" "unprognostic (7.48e-3)" "unprognostic (3.35e-2)" "unprognostic (1.77e-1)" "unprognostic (2.16e-1)" "unprognostic (7.57e-2)" "unprognostic (4.89e-1)" "unprognostic (3.34e-1)" "unprognostic (2.75e-1)" "unprognostic (1.38e-1)" "unprognostic (6.30e-2)" "unprognostic (2.61e-1)" "unprognostic (4.87e-2)" "unprognostic (7.59e-2)" "unprognostic (6.18e-3)" "unprognostic (2.64e-1)" "unprognostic (1.06e-2)" "unprognostic (2.43e-2)" SUMO1 "GMP1, OFC10, PIC1, SMT3C, SMT3H3, SUMO-1, UBL1" ENSG00000116030 "Small ubiquitin like modifier 1" P63165 2 202206182-202238599 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 4 "cerebellum: 6.6" "CAB004269, HPA056956" Supported Supported "Nucleoplasm,Nuclear membrane,Nucleoli,Nuclear bodies" NA NA 10000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 31: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 97: Non-specific - Cellular respiration" 155 "Nuclear membrane, Nuclear bodies" "Nucleoplasm, Nucleoli" "CAB004269: , HPA056956: " "unprognostic (3.87e-2)" "unprognostic (1.62e-1)" "unprognostic (7.18e-2)" "unprognostic (9.08e-2)" "unprognostic (7.38e-2)" "unprognostic (3.43e-1)" "unprognostic (1.39e-1)" "unprognostic (3.25e-1)" "unprognostic (1.83e-2)" "unprognostic (1.02e-1)" "potential prognostic favorable (3.57e-6)" "unprognostic (1.09e-2)" "unprognostic (1.80e-2)" "unprognostic (4.24e-2)" "unprognostic (2.67e-3)" "unprognostic (9.87e-3)" "unprognostic (8.75e-2)" "unprognostic (3.01e-1)" "unprognostic (1.62e-1)" "unprognostic (2.31e-2)" "unprognostic (2.77e-1)" "potential prognostic unfavorable (5.65e-5)" "unprognostic (4.03e-2)" "unprognostic (8.19e-2)" "unprognostic (1.35e-1)" "unprognostic (4.45e-2)" "unprognostic (1.71e-2)" "unprognostic (1.17e-2)" "unprognostic (2.72e-1)" "unprognostic (1.82e-1)" "unprognostic (3.97e-1)" SUMO2 "SMT3B, SMT3H2" ENSG00000188612 "Small ubiquitin like modifier 2" P61956 17 75165586-75182959 "Essential proteins, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 202.2;Late primary spermatocytes: 279.4;Late spermatids: 394.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037314, HPA042123, HPA048064" Supported Supported "Nucleoplasm,Nuclear bodies,Calyx,Connecting piece,Flagellar centriole" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 65: Brain - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 15: Non-specific - Protein processing" 139 "Nucleoplasm, Nuclear bodies" "Calyx, Connecting piece, Flagellar centriole" "CAB037314: , HPA042123: , HPA048064: " "unprognostic (2.87e-2)" "unprognostic (2.12e-1)" "unprognostic (4.84e-2)" "unprognostic (5.78e-3)" "unprognostic (9.77e-3)" "unprognostic (1.52e-2)" "unprognostic (2.00e-1)" "unprognostic (5.15e-2)" "potential prognostic unfavorable (6.50e-4)" "unprognostic (1.76e-2)" "potential prognostic favorable (7.18e-6)" "unprognostic (5.46e-2)" "unprognostic (1.50e-2)" "unprognostic (3.99e-3)" "potential prognostic unfavorable (4.91e-4)" "validated prognostic unfavorable (8.63e-4)" "validated prognostic unfavorable (7.56e-5)" "unprognostic (8.05e-2)" "unprognostic (3.41e-2)" "unprognostic (4.45e-3)" "unprognostic (6.56e-2)" "unprognostic (3.13e-2)" "unprognostic (1.32e-1)" "unprognostic (1.86e-3)" "unprognostic (3.77e-2)" "unprognostic (4.43e-2)" "unprognostic (1.54e-1)" "unprognostic (5.02e-2)" "unprognostic (3.15e-1)" "unprognostic (1.61e-1)" "unprognostic (2.09e-2)" SUMO3 "SMT3A, SMT3H1" ENSG00000184900 "Small ubiquitin like modifier 3" P55854 21 44805617-44818779 "Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Megakaryocytes: 426.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012180, HPA042123, HPA048064" Supported Supported "Nucleoplasm,Nuclear bodies,Calyx,Connecting piece,Flagellar centriole" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 4: Non-specific - Transcription" "Cluster 47: Platelets - Hemostasis" 35 "Nucleoplasm, Nuclear bodies" "Calyx, Connecting piece, Flagellar centriole" "CAB012180: , HPA042123: , HPA048064: " "unprognostic (5.52e-2)" "unprognostic (8.25e-3)" "unprognostic (2.13e-1)" "unprognostic (1.58e-1)" "unprognostic (7.67e-3)" "unprognostic (2.32e-1)" "unprognostic (2.69e-1)" "unprognostic (4.09e-2)" "unprognostic (1.72e-1)" "unprognostic (5.49e-2)" "unprognostic (1.07e-3)" "unprognostic (6.40e-2)" "unprognostic (7.18e-2)" "unprognostic (5.20e-2)" "unprognostic (2.80e-2)" "unprognostic (9.03e-3)" "unprognostic (4.37e-2)" "unprognostic (6.09e-2)" "unprognostic (4.76e-1)" "unprognostic (2.01e-2)" "unprognostic (2.87e-2)" "unprognostic (1.46e-2)" "unprognostic (2.11e-1)" "unprognostic (1.14e-1)" "unprognostic (8.27e-2)" "unprognostic (4.96e-2)" "unprognostic (4.46e-2)" "unprognostic (2.92e-3)" "unprognostic (8.19e-2)" "unprognostic (3.84e-2)" "unprognostic (2.19e-1)" SUMO4 "dJ281H8.4, IDDM5, SMT3H4" ENSG00000177688 "Small ubiquitin like modifier 4" Q6EEV6 6 149400262-149401278 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Colon - Enteric glia cells" "HPA042123, HPA048064" Uncertain Supported "Nucleoplasm,Nuclear bodies,Calyx,Connecting piece,Flagellar centriole" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 6: Non-specific - Immune response" "Cluster 61: BICR 18 - Protein kinases" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 6 "Nucleoplasm, Nuclear bodies" "Calyx, Connecting piece, Flagellar centriole" "HPA042123: , HPA048064: " "unprognostic (7.38e-2)" "unprognostic (1.78e-2)" "unprognostic (4.20e-2)" "potential prognostic unfavorable (3.03e-4)" "unprognostic (1.52e-2)" SUN1 "FLJ12407, KIAA0810, UNC84A" ENSG00000164828 "Sad1 and UNC84 domain containing 1" O94901 7 816615-896435 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Meiosis, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 469.5;Late spermatids: 847.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008346, HPA008461" Enhanced Enhanced "Nuclear membrane" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 24: Non-specific - Transcription" "Cluster 2: Neurons - Nucleosome" "Cluster 67: Non-specific - Unknown function" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 8 "Nuclear membrane" "HPA008346: , HPA008461: " "unprognostic (3.89e-2)" "unprognostic (1.05e-2)" "unprognostic (2.41e-2)" "unprognostic (2.95e-3)" "unprognostic (3.22e-2)" "unprognostic (2.22e-1)" "unprognostic (1.10e-2)" "unprognostic (1.52e-1)" "unprognostic (4.06e-3)" "unprognostic (1.23e-1)" "unprognostic (1.75e-2)" "unprognostic (4.45e-2)" "unprognostic (4.79e-2)" "unprognostic (2.28e-2)" "unprognostic (1.13e-1)" "unprognostic (8.74e-2)" "unprognostic (4.14e-2)" "unprognostic (4.09e-2)" "unprognostic (1.12e-2)" "unprognostic (1.52e-1)" "unprognostic (1.95e-1)" "unprognostic (1.17e-1)" "unprognostic (2.86e-3)" "unprognostic (6.89e-2)" "unprognostic (2.15e-1)" "unprognostic (4.91e-2)" "unprognostic (6.86e-2)" "unprognostic (1.09e-1)" "unprognostic (1.72e-1)" "unprognostic (2.74e-2)" "unprognostic (6.43e-2)" SUN2 UNC84B ENSG00000100242 "Sad1 and UNC84 domain containing 2" Q9UH99 22 38733290-38794143 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Meiosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epicardial cells: 425.3;Esophageal apical cells: 182.7;Oligodendrocytes: 236.2" "Cell type enhanced" "Detected in all" "leukocyte: 212.9;oligodendrocyte: 247.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001209 Supported Supported "Nuclear membrane" NA Yes "Cluster 3: Non-specific - Nuclear processes" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 11: White matter - Signal transduction" "Cluster 6: Leukemia - Signal transduction" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 74 "Nuclear membrane" "HPA001209: " "unprognostic (9.86e-2)" "unprognostic (1.74e-1)" "unprognostic (2.01e-1)" "unprognostic (1.19e-1)" "unprognostic (2.14e-1)" "unprognostic (6.21e-2)" "unprognostic (2.41e-1)" "unprognostic (1.62e-1)" "unprognostic (9.98e-3)" "unprognostic (1.06e-2)" "potential prognostic favorable (8.60e-5)" "unprognostic (2.74e-3)" "unprognostic (2.84e-1)" "unprognostic (1.23e-1)" "unprognostic (4.58e-2)" "unprognostic (1.38e-1)" "unprognostic (1.96e-1)" "unprognostic (1.49e-1)" "unprognostic (3.30e-1)" "unprognostic (5.23e-2)" "unprognostic (3.22e-1)" "unprognostic (2.72e-2)" "unprognostic (1.45e-1)" "unprognostic (3.71e-3)" "unprognostic (6.75e-2)" "unprognostic (2.41e-2)" "unprognostic (4.08e-2)" "unprognostic (1.36e-1)" "unprognostic (4.29e-2)" "unprognostic (1.02e-2)" "unprognostic (4.39e-2)" SUN3 "MGC33329, SUNC1" ENSG00000164744 "Sad1 and UNC84 domain containing 3" Q8TAQ9 7 47987148-48029119 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 298 "testis: 38.8" "Group enriched" "Detected in some" 5 "Early spermatids: 735.3;Late primary spermatocytes: 321.6" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in single" "Testicular Germ Cell Tumor (TCGA): 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Bile duct cancer: 2.0" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA076890 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 4: Non-specific - Transcription" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" "Nucleoplasm, Plasma membrane" "HPA076890: " "unprognostic (1.04e-1)" SUN5 "dJ726C3.1, SPAG4L, TSARG4" ENSG00000167098 "Sad1 and UNC84 domain containing 5" Q8TC36 20 32983773-33004433 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Spermatogenesis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 428 "testis: 42.8" "Cell type enriched" "Detected in some" 4 "Early spermatids: 780.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA048529 Enhanced NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 1 "HPA048529: " SUOX ENSG00000139531 "Sulfite oxidase" P51687 12 55997180-56006641 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 44.9;Hepatocytes: 55.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038208, HPA038209" Approved NA NA 76000 "Cluster 45: Eosinophils - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 69 "HPA038208: , HPA038209: " "unprognostic (1.92e-1)" "unprognostic (1.21e-1)" "unprognostic (4.66e-1)" "unprognostic (2.44e-1)" "unprognostic (1.01e-1)" "potential prognostic favorable (4.95e-4)" "unprognostic (8.17e-2)" "potential prognostic favorable (4.99e-5)" "unprognostic (7.95e-2)" "unprognostic (5.55e-2)" "potential prognostic favorable (1.05e-4)" "unprognostic (2.05e-1)" "potential prognostic favorable (4.45e-5)" "unprognostic (2.31e-2)" "unprognostic (4.05e-2)" "unprognostic (1.49e-2)" "unprognostic (2.56e-1)" "unprognostic (2.76e-1)" "unprognostic (4.66e-2)" "unprognostic (1.86e-1)" "unprognostic (2.52e-1)" "unprognostic (1.78e-3)" "unprognostic (3.17e-1)" "unprognostic (3.43e-1)" "unprognostic (1.23e-1)" "unprognostic (2.41e-1)" "unprognostic (9.55e-2)" "unprognostic (4.48e-3)" "unprognostic (1.76e-1)" "unprognostic (3.37e-2)" "unprognostic (3.03e-1)" SUPT16H "CDC68, FACT, FACTP140, FLJ10857, FLJ14010, SPT16/CDC68" ENSG00000092201 "SPT16 homolog, facilitates chromatin remodeling subunit" Q9Y5B9 14 21351476-21384019 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, Host-virus interaction, Transcription, Transcription regulation" "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythrocyte progenitors: 327.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022551, HPA049787" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA 42000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 17: Non-specific - RNA processing" 150 Nucleoplasm "Nucleoli fibrillar center" "CAB022551: , HPA049787: " "unprognostic (9.43e-2)" "unprognostic (1.18e-1)" "unprognostic (1.85e-2)" "unprognostic (1.21e-1)" "unprognostic (1.51e-2)" "unprognostic (1.60e-1)" "unprognostic (3.73e-2)" "unprognostic (1.48e-2)" "unprognostic (2.60e-1)" "unprognostic (3.10e-3)" "potential prognostic favorable (1.75e-6)" "unprognostic (3.39e-2)" "unprognostic (2.95e-2)" "unprognostic (5.29e-3)" "potential prognostic unfavorable (6.10e-4)" "unprognostic (4.14e-2)" "unprognostic (2.84e-3)" "unprognostic (1.12e-1)" "unprognostic (1.04e-2)" "unprognostic (1.01e-1)" "unprognostic (1.42e-1)" "unprognostic (1.41e-2)" "unprognostic (1.87e-1)" "unprognostic (2.82e-1)" "unprognostic (1.42e-1)" "unprognostic (4.92e-1)" "unprognostic (6.29e-2)" "unprognostic (3.01e-1)" "unprognostic (1.80e-1)" "unprognostic (9.04e-3)" "unprognostic (3.02e-1)" SUPT20H "bA421P11.4, C13orf19, FAM48A, P38IP, SPT20" ENSG00000102710 "SPT20 homolog, SAGA complex component" Q8NEM7 13 37009312-37059713 "Predicted intracellular proteins" "Autophagy, Gastrulation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 53.0" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 528.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038906, HPA038907" Uncertain Approved "Nucleoli fibrillar center" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 39: Testis - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 19: Non-specific - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" 59 "Nucleoli fibrillar center" "HPA038906: , HPA038907: " "unprognostic (4.40e-1)" "unprognostic (3.25e-1)" "unprognostic (1.19e-2)" "unprognostic (3.09e-1)" "unprognostic (1.98e-1)" "unprognostic (1.84e-1)" "unprognostic (4.14e-2)" "unprognostic (1.66e-2)" "unprognostic (5.90e-2)" "unprognostic (3.19e-1)" "unprognostic (3.24e-2)" "unprognostic (1.21e-2)" "unprognostic (1.11e-3)" "unprognostic (2.70e-1)" "unprognostic (1.90e-1)" "unprognostic (6.39e-2)" "unprognostic (2.83e-1)" "unprognostic (3.00e-2)" "unprognostic (3.91e-2)" "unprognostic (2.26e-1)" "unprognostic (4.94e-3)" "unprognostic (5.13e-2)" "unprognostic (3.03e-1)" "unprognostic (2.95e-2)" "unprognostic (1.32e-2)" "unprognostic (2.18e-1)" "unprognostic (6.49e-2)" "unprognostic (1.69e-2)" "unprognostic (1.76e-1)" SUPT20HL1 "FAM48B1, SPT20L" ENSG00000223731 "SUPT20H like 1" X 24360639-24367839 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 4 "Early primary spermatocytes: 6.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" NA NA "Cluster 71: Lymphoma - Inflammatory response" "Cluster 3: Early primary spermatocytes - Early meiosis" SUPT20HL2 FAM48B2 ENSG00000223611 "SUPT20H like 2" P0C7V6 X 24308210-24314069 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "skeletal muscle: 1.8;testis: 1.5" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 7.9;Early primary spermatocytes: 22.5;Epicardial cells: 2.3;Oocytes: 4.6;Sertoli cells: 2.8;Undifferentiated spermatogonia: 4.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Testis - Sertoli cells" NA NA "Cluster 40: Non-specific - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 3: Early primary spermatocytes - Early meiosis" SUPT3H "SPT3, SPT3L" ENSG00000196284 "SPT3 homolog, SAGA and STAGA complex component" O75486 6 44809317-45377953 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024371 Enhanced Supported Nucleoplasm NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 75: Ovary - Mixed function" "Cluster 34: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 109: Neurons - Neuronal signaling" 34 Nucleoplasm "HPA024371: " "unprognostic (1.20e-1)" "unprognostic (2.78e-1)" "unprognostic (6.98e-2)" "unprognostic (4.43e-3)" "unprognostic (6.90e-3)" "unprognostic (2.72e-1)" "unprognostic (2.14e-2)" "unprognostic (5.66e-2)" "unprognostic (3.30e-3)" "unprognostic (6.54e-2)" "unprognostic (3.18e-3)" "unprognostic (1.13e-2)" "unprognostic (9.71e-2)" "validated prognostic unfavorable (4.01e-4)" "validated prognostic unfavorable (1.20e-4)" "unprognostic (2.80e-1)" "unprognostic (2.60e-1)" "unprognostic (9.75e-2)" "unprognostic (1.75e-2)" "unprognostic (4.30e-2)" "unprognostic (2.73e-1)" "unprognostic (2.12e-2)" "unprognostic (1.58e-2)" "unprognostic (1.94e-2)" "unprognostic (5.56e-2)" "unprognostic (1.04e-2)" "unprognostic (4.02e-1)" "unprognostic (2.16e-2)" "unprognostic (7.89e-2)" "unprognostic (4.78e-2)" "unprognostic (1.00e-1)" SUPT4H1 "Spt4, SPT4H, Supt4a, SUPT4H" ENSG00000213246 "SPT4 homolog, DSIF elongation factor subunit" P63272 17 58345175-58353093 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bergmann glia: 12.4;Paneth cells: 15.5;Parietal cells: 12.4;Platelets: 22.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059748 Approved Nucleoplasm NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" 14 Nucleoplasm "HPA059748: " "unprognostic (2.65e-1)" "unprognostic (8.49e-2)" "unprognostic (1.33e-2)" "unprognostic (1.70e-2)" "unprognostic (5.20e-1)" "unprognostic (1.74e-1)" "unprognostic (1.09e-1)" "unprognostic (1.96e-1)" "unprognostic (6.27e-3)" "potential prognostic unfavorable (5.79e-5)" "potential prognostic favorable (3.66e-6)" "unprognostic (1.08e-2)" "unprognostic (6.98e-2)" "unprognostic (1.23e-2)" "potential prognostic unfavorable (6.44e-5)" "unprognostic (2.22e-1)" "unprognostic (7.24e-2)" "unprognostic (1.92e-1)" "unprognostic (2.72e-1)" "unprognostic (2.35e-2)" "unprognostic (8.15e-2)" "unprognostic (1.07e-2)" "unprognostic (3.52e-1)" "unprognostic (2.19e-1)" "unprognostic (1.09e-2)" "unprognostic (6.35e-3)" "unprognostic (2.09e-2)" "unprognostic (8.93e-2)" "unprognostic (4.91e-1)" "unprognostic (5.30e-2)" "unprognostic (9.72e-2)" SUPT5H "FLJ34157, SPT5, SPT5H" ENSG00000196235 "SPT5 homolog, DSIF elongation factor subunit" O00267 19 39436156-39476670 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029273, CAB034370" Supported Supported Nucleoplasm NA NA 3800 "Cluster 29: Non-specific - Unknown function" "Cluster 67: Testis - Mixed function" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 4: Non-specific - Transcription" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 204 Nucleoplasm "CAB034370: , HPA029273: " "potential prognostic favorable (1.21e-4)" "unprognostic (2.40e-2)" "unprognostic (3.84e-1)" "unprognostic (1.70e-3)" "unprognostic (2.08e-1)" "unprognostic (1.91e-2)" "unprognostic (1.86e-2)" "unprognostic (1.31e-1)" "unprognostic (4.17e-1)" "unprognostic (1.30e-1)" "potential prognostic favorable (1.64e-5)" "unprognostic (3.81e-3)" "unprognostic (2.61e-1)" "potential prognostic unfavorable (5.28e-4)" "unprognostic (1.53e-1)" "unprognostic (1.09e-1)" "unprognostic (5.08e-2)" "unprognostic (4.79e-2)" "unprognostic (2.18e-1)" "unprognostic (2.48e-2)" "unprognostic (3.49e-1)" "unprognostic (1.82e-1)" "unprognostic (1.91e-2)" "unprognostic (3.42e-3)" "unprognostic (9.76e-2)" "unprognostic (7.49e-2)" "unprognostic (7.17e-2)" "unprognostic (1.22e-1)" "unprognostic (4.88e-2)" "unprognostic (8.09e-2)" "unprognostic (9.43e-2)" SUPT6H "KIAA0162, SPT6H" ENSG00000109111 "SPT6 homolog, histone chaperone and transcription elongation factor" Q7KZ85 17 28662198-28702679 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing, mRNA transport, Transcription, Transport" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 344.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012416, HPA036382" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 4600 "Cluster 29: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Breast cancer - Unknown function" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 46 "Nucleoplasm, Cytosol" "Plasma membrane" "CAB012416: , HPA036382: " "unprognostic (2.56e-3)" "unprognostic (2.96e-1)" "unprognostic (6.46e-2)" "unprognostic (2.67e-2)" "unprognostic (3.63e-1)" "unprognostic (1.17e-1)" "unprognostic (6.65e-2)" "unprognostic (2.05e-1)" "unprognostic (1.05e-1)" "unprognostic (8.08e-3)" "validated prognostic favorable (1.48e-5)" "validated prognostic favorable (5.23e-4)" "unprognostic (9.81e-2)" "potential prognostic unfavorable (5.16e-4)" "unprognostic (1.67e-1)" "unprognostic (8.98e-2)" "unprognostic (1.18e-1)" "unprognostic (1.65e-1)" "unprognostic (1.22e-2)" "unprognostic (1.47e-2)" "unprognostic (7.15e-2)" "unprognostic (4.54e-2)" "unprognostic (5.26e-3)" "unprognostic (3.33e-2)" "unprognostic (6.63e-3)" "unprognostic (1.15e-3)" "unprognostic (8.15e-2)" "unprognostic (3.19e-1)" "unprognostic (2.20e-1)" "unprognostic (2.20e-3)" "unprognostic (4.00e-1)" SUPT7L "KIAA0764, SPT7L, STAF65, STAF65gamma" ENSG00000119760 "SPT7 like, STAGA complex subunit gamma" O94864 2 27650809-27663840 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039565, HPA063643" Uncertain Supported Nucleoplasm NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 64: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 7: Non-specific - Transcription" 33 Nucleoplasm "HPA039565: , HPA063643: " "unprognostic (1.77e-1)" "unprognostic (5.16e-2)" "potential prognostic favorable (5.70e-4)" "unprognostic (2.72e-2)" "unprognostic (1.12e-1)" "unprognostic (3.84e-1)" "unprognostic (9.56e-2)" "potential prognostic favorable (2.33e-4)" "unprognostic (2.56e-1)" "unprognostic (2.02e-3)" "unprognostic (2.13e-1)" "unprognostic (4.43e-1)" "unprognostic (6.46e-2)" "potential prognostic unfavorable (1.65e-8)" "unprognostic (1.80e-2)" "unprognostic (1.80e-1)" "unprognostic (5.60e-2)" "unprognostic (3.92e-2)" "unprognostic (1.74e-2)" "unprognostic (1.65e-1)" "unprognostic (1.99e-2)" "unprognostic (5.55e-2)" "unprognostic (3.60e-3)" "unprognostic (7.78e-2)" "unprognostic (2.38e-2)" "unprognostic (3.26e-2)" "unprognostic (7.95e-3)" "unprognostic (2.53e-1)" "unprognostic (1.72e-1)" "unprognostic (3.84e-2)" "unprognostic (5.33e-2)" SUPV3L1 SUV3 ENSG00000156502 "Suv3 like RNA helicase" Q8IYB8 10 69180234-69209099 "Enzymes, Essential proteins, Predicted intracellular proteins" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038380, HPA038405" Supported Supported Mitochondria NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 26 Mitochondria "HPA038380: , HPA038405: " "unprognostic (1.62e-1)" "unprognostic (3.73e-2)" "unprognostic (6.41e-2)" "unprognostic (9.64e-2)" "unprognostic (1.35e-2)" "unprognostic (1.98e-1)" "unprognostic (4.15e-2)" "potential prognostic favorable (2.78e-6)" "unprognostic (1.72e-1)" "unprognostic (3.06e-2)" "potential prognostic favorable (1.15e-5)" "unprognostic (7.46e-3)" "unprognostic (2.65e-1)" "unprognostic (4.53e-2)" "unprognostic (5.26e-2)" "unprognostic (4.62e-2)" "unprognostic (3.46e-2)" "unprognostic (9.91e-2)" "unprognostic (5.66e-2)" "unprognostic (1.71e-2)" "unprognostic (8.52e-2)" "unprognostic (1.06e-1)" "unprognostic (1.91e-2)" "unprognostic (4.64e-2)" "unprognostic (1.09e-3)" "unprognostic (1.90e-1)" "unprognostic (2.01e-1)" "unprognostic (9.48e-2)" "unprognostic (2.82e-1)" "unprognostic (2.44e-3)" "unprognostic (1.78e-1)" SURF1 SHY1 ENSG00000148290 "SURF1 cytochrome c oxidase assembly factor" Q15526 9 133351758-133356676 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Charcot-Marie-Tooth disease, Disease variant, Leigh syndrome, Neurodegeneration, Neuropathy, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 173.5;Epididymal principal cells: 186.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB033946 Uncertain NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 70: Non-specific - Protein processing" "Cluster 27: Non-specific - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 97: Non-specific - Cellular respiration" 10 "CAB033946: " "unprognostic (5.40e-3)" "unprognostic (5.23e-2)" "unprognostic (3.35e-1)" "potential prognostic favorable (2.80e-4)" "unprognostic (1.56e-1)" "unprognostic (4.08e-3)" "unprognostic (2.42e-1)" "unprognostic (2.32e-1)" "unprognostic (1.30e-1)" "unprognostic (8.88e-2)" "potential prognostic favorable (2.12e-4)" "unprognostic (5.65e-2)" "potential prognostic favorable (1.16e-4)" "unprognostic (1.43e-1)" "unprognostic (2.07e-1)" "unprognostic (4.33e-2)" "unprognostic (3.59e-1)" "unprognostic (4.34e-2)" "unprognostic (7.12e-2)" "unprognostic (4.12e-1)" "unprognostic (1.21e-1)" "unprognostic (1.24e-1)" "unprognostic (2.38e-1)" "unprognostic (3.26e-1)" "unprognostic (2.06e-1)" "unprognostic (2.96e-1)" "unprognostic (4.27e-1)" "unprognostic (1.46e-1)" "unprognostic (5.18e-2)" "unprognostic (1.86e-1)" "unprognostic (1.08e-1)" SURF2 ENSG00000148291 "Surfeit 2" Q15527 9 133356550-133361158 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 102.1" "Cell type enhanced" "Detected in many" "Early spermatids: 418.6;Late primary spermatocytes: 470.6;Late spermatids: 1267.7;Oocytes: 294.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044340, HPA052213, HPA059710" Approved Approved "Nucleoplasm,Nucleoli,Nucleoli rim" No No "Cluster 3: Non-specific - Nuclear processes" "Cluster 67: Testis - Mixed function" "Cluster 16: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 12 "Nucleoli, Nucleoli rim" Nucleoplasm "HPA044340: , HPA052213: , HPA059710: " "unprognostic (2.27e-3)" "unprognostic (1.62e-1)" "unprognostic (2.55e-1)" "unprognostic (2.61e-2)" "unprognostic (5.91e-3)" "potential prognostic unfavorable (1.06e-4)" "unprognostic (1.49e-1)" "unprognostic (6.75e-3)" "unprognostic (1.32e-2)" "unprognostic (1.73e-1)" "potential prognostic favorable (8.65e-4)" "unprognostic (1.57e-2)" "unprognostic (1.03e-1)" "unprognostic (5.84e-3)" "unprognostic (4.98e-3)" "unprognostic (2.88e-1)" "unprognostic (4.08e-2)" "unprognostic (2.06e-2)" "unprognostic (2.90e-2)" "unprognostic (3.75e-1)" "unprognostic (8.57e-2)" "unprognostic (9.73e-3)" "unprognostic (2.77e-1)" "unprognostic (2.40e-2)" "unprognostic (2.16e-1)" "unprognostic (1.17e-2)" "unprognostic (3.27e-1)" "unprognostic (3.63e-1)" "unprognostic (2.41e-1)" "unprognostic (2.27e-2)" "unprognostic (8.65e-2)" SURF4 "ERV29, FLJ22993, MGC102753" ENSG00000148248 "Surfeit 4" O15260 9 133361450-133376166 "Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 24.6;Bergmann glia: 28.6;Brain excitatory neurons: 27.4;Brain inhibitory neurons: 24.8;Choroid plexus epithelial cells: 27.4;Distal convoluted tubule cells: 27.0;Loop of henle epithelial cells: 28.2;Microglia: 29.9;Oligodendrocyte progenitor cells: 35.0;Oligodendrocytes: 41.0;Other brain neurons: 28.5;Papillary tip epithelial cells: 30.1;Podocytes: 25.8;Proximal tubule cells: 25.6;Renal collecting duct intercalated cells: 25.1;Renal collecting duct principal cells: 27.6;Renal connecting tubule cells: 24.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064613 Approved Supported "Nuclear membrane,Endoplasmic reticulum,Golgi apparatus,Cytosol" NA Yes 110000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 70: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 98: Neurons - Neurotransmission & signaling" 18 "Nuclear membrane, Endoplasmic reticulum, Golgi apparatus" Cytosol "HPA064613: " "unprognostic (1.27e-1)" "potential prognostic unfavorable (9.06e-4)" "unprognostic (3.67e-1)" "unprognostic (6.57e-3)" "unprognostic (5.76e-2)" "unprognostic (1.18e-3)" "unprognostic (2.67e-2)" "unprognostic (1.31e-1)" "potential prognostic unfavorable (2.50e-4)" "unprognostic (2.54e-1)" "unprognostic (1.36e-3)" "unprognostic (3.03e-1)" "unprognostic (2.46e-2)" "potential prognostic unfavorable (3.36e-4)" "unprognostic (1.30e-3)" "unprognostic (2.53e-2)" "unprognostic (4.52e-3)" "unprognostic (1.59e-2)" "unprognostic (3.14e-1)" "unprognostic (9.70e-2)" "unprognostic (3.11e-1)" "unprognostic (2.16e-2)" "unprognostic (1.77e-1)" "unprognostic (2.09e-1)" "unprognostic (2.52e-1)" "unprognostic (8.48e-2)" "unprognostic (1.86e-1)" "unprognostic (3.45e-2)" "unprognostic (4.35e-1)" "unprognostic (2.83e-2)" "unprognostic (5.47e-2)" SURF6 "FLJ30322, RRP14" ENSG00000148296 "Surfeit 6" O75683 9 133328776-133336188 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 10.1;Brain inhibitory neurons: 8.8;Distal convoluted tubule cells: 9.1;Loop of henle epithelial cells: 10.0;Microglia: 13.4;Other brain neurons: 12.7;Paneth cells: 11.6;Papillary tip epithelial cells: 13.3;Proximal tubule cells: 13.7;Renal collecting duct intercalated cells: 9.1;Renal collecting duct principal cells: 9.0;Renal connecting tubule cells: 10.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023608, HPA074622" Approved Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 30: Non-specific - DNA binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 98: Neurons - Neurotransmission & signaling" 204 "Nucleoli, Nucleoli rim" "Nucleoplasm, Mitotic chromosome" "HPA023608: , HPA074622: " "unprognostic (1.16e-1)" "unprognostic (1.51e-2)" "unprognostic (1.81e-3)" "unprognostic (7.43e-2)" "unprognostic (1.06e-2)" "unprognostic (8.17e-2)" "unprognostic (1.07e-1)" "potential prognostic favorable (2.61e-4)" "unprognostic (2.08e-1)" "unprognostic (1.76e-1)" "potential prognostic favorable (6.85e-4)" "unprognostic (1.86e-3)" "unprognostic (1.09e-2)" "potential prognostic unfavorable (1.89e-4)" "unprognostic (9.44e-3)" "unprognostic (2.67e-1)" "unprognostic (6.73e-2)" "unprognostic (6.63e-2)" "unprognostic (2.38e-3)" "unprognostic (7.18e-2)" "unprognostic (1.08e-1)" "unprognostic (4.43e-2)" "unprognostic (4.21e-1)" "unprognostic (1.95e-3)" "unprognostic (1.19e-2)" "unprognostic (1.24e-2)" "unprognostic (4.08e-2)" "unprognostic (3.63e-2)" "unprognostic (4.72e-1)" "unprognostic (1.80e-1)" "potential prognostic favorable (2.47e-5)" SUSD1 DKFZP761E1824 ENSG00000106868 "Sushi domain containing 1" Q6UWL2 9 112040783-112175297 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "pDCs: 233.7;Platelets: 220.0;Renal collecting duct intercalated cells: 254.3;Renal collecting duct principal cells: 245.7;Renal connecting tubule cells: 224.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "eosinophil: 11.1;plasmacytoid DC: 44.3" "Group enriched" "Detected in many" 5 "dendritic cells: 44.3;granulocytes: 11.1" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Kidney - Fibroblasts, Lung - Macrophages, Spleen - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA048554 Approved Approved Nucleoplasm "Intracellular and membrane" "No annotated function" NA NA 230000 "Cluster 29: Non-specific - Unknown function" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 1: Neurons - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" Nucleoplasm "HPA048554: " "unprognostic (2.86e-1)" "unprognostic (6.12e-2)" "unprognostic (2.77e-1)" "unprognostic (1.19e-2)" "unprognostic (4.60e-2)" "unprognostic (2.34e-1)" "unprognostic (1.78e-2)" "unprognostic (1.76e-1)" "unprognostic (1.57e-2)" "unprognostic (1.11e-1)" "potential prognostic favorable (9.04e-5)" "unprognostic (1.56e-1)" "unprognostic (8.92e-2)" "unprognostic (4.18e-3)" "unprognostic (2.89e-1)" "unprognostic (4.61e-2)" "unprognostic (2.79e-2)" "unprognostic (2.60e-3)" "unprognostic (3.35e-1)" "unprognostic (1.12e-3)" "unprognostic (3.01e-1)" "unprognostic (1.64e-1)" "unprognostic (1.15e-1)" "unprognostic (1.48e-1)" "unprognostic (2.90e-2)" "unprognostic (1.23e-2)" "unprognostic (1.18e-2)" "unprognostic (3.21e-3)" "unprognostic (2.30e-1)" "unprognostic (1.52e-1)" "unprognostic (5.99e-2)" SUSD2 "BK65A6.2, FLJ22778, W5C5" ENSG00000099994 "Sushi domain containing 2" Q9UGT4 22 24181487-24189106 "Predicted membrane proteins" Receptor "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 59.3;lung: 94.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 248.9;Alveolar cells type 2: 144.2;Enterocytes: 149.1;Hepatic stellate cells: 51.6;Pericytes: 36.3;Pituicytes/FSCs: 35.6;Syncytiotrophoblasts: 32.3;Transitional alveolar cells: 145.7;Vascular smooth muscle cells: 73.1" "Cell type enhanced" "Detected in some" "pericyte: 15.0;vascular associated smooth muscle cell: 34.2" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 160.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 65.6;Rhabdoid: 35.5" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Fibroblasts, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatic stellate cells, Lung - Alveolar cells type 1, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 7 "spinal cord: 14.4" HPA004117 Enhanced Approved "Plasma membrane" NA NA 2600000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 19: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 81: Alveolar cells - Lung function" 14 "Plasma membrane" "HPA004117: " "unprognostic (1.47e-1)" "unprognostic (6.60e-3)" "potential prognostic favorable (9.37e-4)" "unprognostic (2.76e-1)" "unprognostic (2.05e-1)" "unprognostic (1.47e-2)" "unprognostic (4.06e-2)" "unprognostic (2.99e-2)" "unprognostic (3.23e-2)" "unprognostic (7.46e-2)" "potential prognostic favorable (3.57e-5)" "unprognostic (1.19e-2)" "unprognostic (3.57e-2)" "unprognostic (3.27e-2)" "unprognostic (1.54e-1)" "unprognostic (1.18e-3)" "unprognostic (2.40e-2)" "potential prognostic unfavorable (3.81e-4)" "unprognostic (4.24e-1)" "unprognostic (3.13e-3)" "unprognostic (6.18e-2)" "unprognostic (4.10e-3)" "unprognostic (1.21e-1)" "unprognostic (1.48e-1)" "unprognostic (1.29e-1)" "unprognostic (1.73e-2)" "unprognostic (2.64e-1)" "unprognostic (3.09e-2)" "unprognostic (6.01e-2)" "unprognostic (1.62e-2)" "unprognostic (3.39e-1)" SUSD3 MGC26847 ENSG00000157303 "Sushi domain containing 3" Q96L08 9 93058688-93085133 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 53.5;testis: 76.3" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 51.8;Conjunctival goblet cells: 52.4;Granulosa cells: 240.1;Hepatocytes: 89.3;Hofbauer cells: 107.3;Megakaryocytes: 117.5;Microglia: 101.4;Neutrophil progenitors: 77.6;Platelets: 122.5;Sertoli cells: 100.9" "Cell type enriched" "Detected in some" 4 "central nervous system macrophage: 126.7" "Group enriched" "Detected in all" 4 "Breast Invasive Carcinoma (TCGA): 100.3;Kidney Chromophobe (TCGA): 45.7;Ovary Serous Cystadenocarcinoma (TCGA): 55.5;Testicular Germ Cell Tumor (TCGA): 41.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 6 "breast cancer: 23.6;Leukemia: 31.6;lymphoma: 46.4;Myeloma: 22.9" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Kidney - Proximal tubular cells, Lung - T-cells, Spleen - B-cells (Spleen), Testis - Sertoli cells, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042310 Uncertain NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 39: Testis - Nuclear processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 22 "HPA042310: " "unprognostic (1.24e-1)" "unprognostic (1.75e-3)" "unprognostic (2.01e-2)" "unprognostic (1.88e-2)" "unprognostic (5.97e-2)" "unprognostic (1.91e-1)" "unprognostic (1.03e-1)" "unprognostic (2.59e-3)" "unprognostic (3.96e-2)" "unprognostic (5.58e-2)" "unprognostic (7.70e-3)" "unprognostic (6.77e-2)" "unprognostic (2.46e-1)" "unprognostic (1.48e-3)" "unprognostic (1.57e-1)" "unprognostic (6.98e-3)" "unprognostic (5.50e-2)" "unprognostic (1.75e-1)" "unprognostic (6.29e-2)" "unprognostic (4.07e-3)" "unprognostic (9.40e-2)" "unprognostic (6.60e-2)" "unprognostic (3.27e-1)" "unprognostic (3.37e-1)" "unprognostic (5.86e-2)" "unprognostic (2.91e-2)" "unprognostic (2.58e-1)" "unprognostic (3.55e-1)" "unprognostic (9.19e-2)" "unprognostic (8.51e-3)" "unprognostic (7.92e-2)" SUSD4 FLJ10052 ENSG00000143502 "Sushi domain containing 4" Q5VX71 1 223220819-223364233 "Predicted intracellular proteins, Predicted membrane proteins" "Complement pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 47.5;esophagus: 46.6" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 179.1;Brain inhibitory neurons: 177.9;Distal convoluted tubule cells: 144.1;Esophageal apical cells: 230.1;Esophageal suprabasal cells: 272.1;Loop of henle epithelial cells: 145.9;Oligodendrocyte progenitor cells: 155.1;Retinal amacrine cells: 240.9;Somatotrophs: 282.4" "Cell type enhanced" "Detected in many" "hippocampal CA4: 722.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory CD4 T-cell: 6.8;naive CD4 T-cell: 10.2" "Lineage enriched" "Detected in single" 40 "T-cells: 10.2" "Cancer enhanced" "Detected in many" "breast cancer: 16.1" "Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary gland basal cells, Pituitary gland - Somatotropes, Prostate - Urothelial cells, Skin - Outer root sheath cells, Spleen - T-cells, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058296 Uncertain Approved Vesicles "Intracellular and membrane" "Complement pathway" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 29: Forebrain - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" Vesicles "HPA058296: " "unprognostic (7.43e-3)" "unprognostic (9.79e-2)" "unprognostic (1.12e-2)" "unprognostic (7.38e-3)" "unprognostic (4.76e-2)" "unprognostic (3.51e-1)" "unprognostic (3.66e-3)" "unprognostic (1.36e-1)" "unprognostic (3.77e-1)" "potential prognostic unfavorable (3.69e-8)" "unprognostic (2.99e-3)" "unprognostic (1.11e-3)" "unprognostic (2.36e-2)" "unprognostic (1.35e-1)" "unprognostic (2.73e-3)" "unprognostic (1.02e-1)" "unprognostic (3.22e-3)" "unprognostic (2.11e-2)" "unprognostic (7.63e-2)" "unprognostic (1.47e-1)" "unprognostic (2.87e-3)" "unprognostic (1.10e-1)" "unprognostic (1.21e-1)" "unprognostic (3.02e-1)" "unprognostic (1.31e-1)" "unprognostic (3.02e-2)" "unprognostic (1.43e-1)" "unprognostic (2.72e-1)" "unprognostic (1.34e-2)" SUSD5 KIAA0527 ENSG00000173705 "Sushi domain containing 5" O60279 3 33150043-33218810 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 26 "blood vessel: 170.2" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 30.9;Melanocytes: 25.4;Mesothelial cells: 17.8;Oligodendrocyte progenitor cells: 114.0;Retinal pigment epithelial cells: 34.1;Undifferentiated spermatogonia: 44.0;Vascular smooth muscle cells: 142.8" "Cell type enhanced" "Detected in many" "oligodendrocyte precursor cell: 132.9;vascular associated smooth muscle cell: 149.3" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 10.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Testis - Spermatogonia, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052788 Uncertain Uncertain "Golgi apparatus,Vesicles" NA NA 3600000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 53: Neurons - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 62: Smooth muscle cells - Muscle contraction" "Golgi apparatus, Vesicles" "HPA052788: " "unprognostic (8.49e-2)" "unprognostic (4.72e-1)" "unprognostic (3.89e-2)" "unprognostic (1.15e-1)" "validated prognostic favorable (7.58e-4)" "validated prognostic favorable (1.38e-4)" "unprognostic (1.62e-1)" "unprognostic (9.70e-2)" "unprognostic (5.22e-2)" "unprognostic (1.36e-1)" "unprognostic (6.16e-2)" "unprognostic (1.35e-1)" "unprognostic (1.53e-1)" "unprognostic (2.12e-1)" "unprognostic (1.59e-1)" "unprognostic (3.70e-2)" "unprognostic (8.17e-3)" SUSD6 KIAA0247 ENSG00000100647 "Sushi domain containing 6" Q92537 14 69611596-69715144 "Predicted membrane proteins" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Neutrophils: 1672.3" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 549.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003419, HPA030464" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 49: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 70: DU4475 - Unknown function" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 7 "Plasma membrane" Cytosol "HPA003419: , HPA030464: " "unprognostic (3.46e-2)" "unprognostic (1.88e-1)" "unprognostic (2.34e-1)" "unprognostic (2.45e-1)" "unprognostic (3.99e-2)" "unprognostic (2.00e-1)" "unprognostic (3.33e-1)" "unprognostic (1.25e-1)" "unprognostic (2.82e-1)" "potential prognostic favorable (1.10e-5)" "unprognostic (2.92e-3)" "unprognostic (2.89e-2)" "unprognostic (1.93e-1)" "unprognostic (5.09e-2)" "unprognostic (2.93e-1)" "unprognostic (1.67e-2)" "unprognostic (1.08e-1)" "unprognostic (1.78e-2)" "unprognostic (4.01e-2)" "unprognostic (1.08e-1)" "unprognostic (1.52e-1)" "unprognostic (7.47e-2)" "unprognostic (1.59e-1)" "unprognostic (9.68e-2)" "unprognostic (1.08e-1)" "unprognostic (2.48e-2)" "unprognostic (1.01e-1)" "unprognostic (3.35e-2)" "unprognostic (2.61e-1)" SUV39H1 "KMT1A, SUV39H" ENSG00000101945 "SUV39H1 histone lysine methyltransferase" O43463 X 48695554-48709016 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Differentiation, Host-virus interaction, rRNA processing, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 21.3;Epididymal principal cells: 16.7;Extravillous trophoblasts: 40.0;Megakaryocyte progenitors: 14.3;Migrating cytotrophoblasts: 13.9;Monocyte progenitors: 13.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Stomach - Mitotic cells (Stomach), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA Yes "Cluster 3: Non-specific - Nuclear processes" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 1: Neurons - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 27: Non-specific - Cell proliferation" 147 "unprognostic (6.18e-2)" "unprognostic (3.13e-2)" "unprognostic (5.50e-2)" "unprognostic (6.45e-2)" "unprognostic (4.96e-2)" "unprognostic (4.26e-2)" "unprognostic (1.41e-1)" "unprognostic (2.01e-1)" "unprognostic (2.80e-2)" "unprognostic (2.30e-2)" "unprognostic (3.50e-2)" "unprognostic (3.91e-2)" "unprognostic (1.11e-1)" "unprognostic (1.85e-3)" "potential prognostic unfavorable (9.10e-6)" "unprognostic (5.02e-3)" "potential prognostic unfavorable (2.16e-5)" "unprognostic (8.38e-2)" "unprognostic (1.30e-2)" "unprognostic (1.48e-1)" "unprognostic (5.39e-2)" "unprognostic (2.86e-1)" "unprognostic (2.58e-1)" "unprognostic (1.12e-1)" "unprognostic (9.24e-2)" "unprognostic (8.90e-2)" "unprognostic (9.61e-2)" "unprognostic (1.02e-1)" "unprognostic (1.72e-1)" "unprognostic (1.56e-1)" "unprognostic (2.09e-1)" SUV39H2 "FLJ23414, KMT1B" ENSG00000152455 "SUV39H2 histone lysine methyltransferase" Q9H5I1 10 14878820-14904315 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Differentiation, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "testis: 36.6" "Group enriched" "Detected in many" 4 "Early spermatids: 477.2;Late primary spermatocytes: 284.2;Late spermatids: 132.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - Mitotic cells (Spleen), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045901, HPA057554" Enhanced Uncertain Mitochondria NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 57: Testis - Spermatogenesis" "Cluster 2: Neurons - Nucleosome" "Cluster 52: Non-specific - Mitochondria" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 36 Mitochondria "HPA045901: , HPA057554: " "unprognostic (2.77e-1)" "unprognostic (1.73e-3)" "unprognostic (1.64e-1)" "potential prognostic unfavorable (1.03e-4)" "unprognostic (3.22e-2)" "unprognostic (2.70e-1)" "unprognostic (2.93e-2)" "potential prognostic favorable (9.26e-5)" "unprognostic (2.24e-2)" "potential prognostic unfavorable (4.67e-4)" "unprognostic (4.58e-3)" "unprognostic (1.23e-1)" "unprognostic (5.63e-2)" "validated prognostic unfavorable (1.03e-4)" "validated prognostic unfavorable (1.25e-4)" "unprognostic (2.07e-2)" "potential prognostic unfavorable (5.58e-4)" "unprognostic (2.04e-3)" "unprognostic (2.31e-1)" "unprognostic (1.17e-1)" "unprognostic (3.22e-1)" "unprognostic (1.40e-1)" "unprognostic (1.30e-3)" "unprognostic (2.05e-2)" "unprognostic (1.51e-3)" "unprognostic (4.01e-1)" "unprognostic (3.24e-1)" "unprognostic (5.53e-2)" "unprognostic (1.69e-1)" "unprognostic (2.25e-1)" "unprognostic (1.22e-1)" SUZ12 "CHET9, JJAZ1, KIAA0160" ENSG00000178691 "SUZ12 polycomb repressive complex 2 subunit" Q15022 17 31937007-32001038 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Cancer-related genes, Disease variant, Intellectual disability, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057436 Approved Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Nuclear bodies" Yes No "Cluster 34: B-cells - Unknown function" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 16: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 107 "Nucleoplasm, Nucleoli, Nuclear bodies" "Nucleoli rim" "HPA057436: " "unprognostic (3.39e-1)" "unprognostic (1.51e-1)" "unprognostic (3.29e-1)" "unprognostic (1.64e-1)" "unprognostic (3.26e-3)" "unprognostic (2.57e-2)" "unprognostic (2.86e-1)" "unprognostic (7.82e-2)" "unprognostic (1.85e-1)" "potential prognostic unfavorable (1.28e-4)" "potential prognostic favorable (2.25e-5)" "unprognostic (1.63e-2)" "unprognostic (5.03e-2)" "unprognostic (2.16e-3)" "potential prognostic unfavorable (3.04e-5)" "unprognostic (1.71e-2)" "unprognostic (5.71e-2)" "unprognostic (5.86e-2)" "unprognostic (7.05e-2)" "unprognostic (3.37e-2)" "unprognostic (6.60e-3)" "unprognostic (2.15e-2)" "unprognostic (6.22e-3)" "unprognostic (4.58e-2)" "unprognostic (4.65e-3)" "unprognostic (1.00e-1)" "unprognostic (1.24e-1)" "unprognostic (1.63e-1)" "unprognostic (2.21e-1)" "unprognostic (4.83e-2)" "unprognostic (3.27e-2)" SV2A "KIAA0736, SV2" ENSG00000159164 "Synaptic vesicle glycoprotein 2A" Q7L0J3 1 149903318-149917844 "FDA approved drug targets, Predicted membrane proteins" "Neurotransmitter transport, Transport" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 114.9;parathyroid gland: 45.5" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 84.1;Brain inhibitory neurons: 130.5;Corticotrophs: 34.9;Oligodendrocyte progenitor cells: 49.8;Other brain neurons: 92.5;Retinal amacrine cells: 134.1;Retinal bipolar cells: 60.6;Retinal ganglion cells: 42.5;Retinal horizontal cells: 40.1" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 6 "Glioblastoma Multiforme (TCGA): 49.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 54.3" "Adipose subcutaneous - Smooth muscle cells, Colon - Colon enteroendocrine cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002226, HPA007863" Enhanced Approved Cytosol NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 7 Cytosol "CAB002226: , HPA007863: " "unprognostic (9.08e-2)" "unprognostic (2.09e-2)" "unprognostic (1.82e-1)" "unprognostic (3.16e-3)" "unprognostic (1.07e-1)" "unprognostic (2.68e-1)" "unprognostic (3.55e-1)" "unprognostic (3.26e-3)" "unprognostic (1.82e-1)" "unprognostic (2.65e-2)" "unprognostic (1.74e-1)" "unprognostic (1.71e-1)" "unprognostic (5.58e-3)" "unprognostic (9.70e-2)" "unprognostic (2.81e-1)" "unprognostic (1.31e-1)" "unprognostic (2.35e-3)" "unprognostic (3.20e-1)" "unprognostic (1.45e-1)" "unprognostic (8.72e-3)" "unprognostic (3.08e-1)" "unprognostic (1.37e-1)" "unprognostic (1.23e-1)" "unprognostic (2.24e-2)" "unprognostic (2.63e-1)" "unprognostic (8.60e-3)" "unprognostic (1.05e-1)" "unprognostic (1.24e-2)" "unprognostic (4.06e-1)" SV2B "HsT19680, KIAA0735" ENSG00000185518 "Synaptic vesicle glycoprotein 2B" Q7L1I2 15 91099950-91302565 "Predicted membrane proteins, Transporters" "Neurotransmitter transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 23 "brain: 27.3;retina: 52.2" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 375.6;Cone photoreceptor cells: 614.8;Corticotrophs: 402.0;Müller glia: 124.5;Other brain neurons: 101.8;Retinal bipolar cells: 457.7;Retinal ganglion cells: 173.8;Rod photoreceptor cells: 586.9" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 1.6;lung cancer: 1.0" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells, Pituitary gland - Corticotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046247 Approved NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 35: Neurons - Synaptic function & neurogenesis" 3 "HPA046247: " "unprognostic (4.34e-1)" "unprognostic (2.01e-1)" "unprognostic (2.62e-3)" SV2C ENSG00000122012 "Synaptic vesicle glycoprotein 2C" Q496J9 5 76083383-76353939 "Predicted membrane proteins, Transporters" "Neurotransmitter transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 16.6" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 287.0;Granulosa cells: 233.6;Lactotrophs: 129.0;Neuroendocrine cells: 193.1;Other brain neurons: 338.3;Retinal ganglion cells: 231.8;Somatotrophs: 419.7" "Cell type enhanced" "Detected in many" "eccentric medium spiny neuron: 542.8;medium spiny neuron: 578.8;midbrain-derived inhibitory: 351.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 15 "basophil: 1.5" "Lineage enriched" "Detected in single" 15 "granulocytes: 1.5" "Cancer enriched" "Detected in single" 10 "Neuroblastoma: 9.0" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Prostate - Prostate basal glandular cells, Skin - Inner root sheath cells, Stomach - Gastric enteroendocrine cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040722, HPA040770" Supported Supported Nucleoplasm,Vesicles NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 78: Brain - Neuronal signaling" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 1 "Nucleoplasm, Vesicles" "HPA040722: , HPA040770: " "unprognostic (2.29e-1)" SVBP "CCDC23, MGC45441" ENSG00000177868 "Small vasohibin binding protein" Q8N300 1 42807052-42817397 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 159.4;Early primary spermatocytes: 140.0;Early spermatids: 147.3;Late primary spermatocytes: 207.3;Oocytes: 147.4;Undifferentiated spermatogonia: 142.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008507 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" "Secreted to blood" "No annotated function" Yes No "Cluster 25: Non-specific - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 106: Spermatogonia - Spermatogonial differentiation" "Nucleoplasm, Nuclear bodies, Cytosol" "HPA008507: " "unprognostic (3.86e-1)" "unprognostic (2.22e-1)" "unprognostic (3.55e-2)" "unprognostic (2.36e-1)" "unprognostic (1.47e-1)" "unprognostic (2.45e-1)" "unprognostic (5.48e-3)" "unprognostic (1.75e-1)" "unprognostic (1.68e-1)" "potential prognostic favorable (1.70e-4)" "unprognostic (3.08e-2)" "unprognostic (1.53e-2)" "potential prognostic unfavorable (8.45e-7)" "unprognostic (7.07e-2)" "unprognostic (2.97e-2)" "unprognostic (2.53e-2)" "unprognostic (7.43e-2)" "unprognostic (5.97e-2)" "unprognostic (1.53e-1)" "unprognostic (2.08e-1)" "unprognostic (1.70e-1)" "unprognostic (4.21e-1)" "unprognostic (7.92e-2)" "unprognostic (6.65e-2)" "unprognostic (6.22e-3)" "potential prognostic unfavorable (8.22e-4)" "unprognostic (1.01e-1)" "unprognostic (1.11e-2)" "unprognostic (1.37e-1)" SVEP1 "bA427L11.3, C9orf13, FLJ13529, POLYDOM" ENSG00000165124 "Sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1" Q4LDE5 9 110365248-110579880 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 36.6;placenta: 58.3" "Cell type enhanced" "Detected in many" "Adipocytes: 723.3;Ependymal cells: 122.0;Epicardial cells: 213.8;Fibro-adipogenic progenitors: 856.6;Fibroblasts: 349.5;Mesothelial cells: 470.3;Oligodendrocytes: 156.6;Syncytiotrophoblasts: 609.6" "Cell type enhanced" "Detected in all" "upper rhombic lip: 269.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 10.8;testis cancer: 10.0" "Adrenal gland - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblasts_1, Spleen - Fibroblasts_1" "Region enhanced" "Detected in some" "cerebellum: 2.8" "Region enriched" "Detected in all" 4 "cerebellum: 29.1" "HPA020610, HPA021520" Enhanced "Intracellular and membrane" "Cell adhesion" NA NA 100000000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 6: Non-specific - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" "HPA020610: , HPA021520: " "unprognostic (5.23e-2)" "unprognostic (1.84e-1)" "unprognostic (1.61e-2)" "unprognostic (1.47e-2)" "unprognostic (1.87e-1)" "unprognostic (2.73e-1)" "unprognostic (4.53e-1)" "unprognostic (6.91e-2)" "unprognostic (2.12e-1)" "unprognostic (6.21e-2)" "unprognostic (2.71e-3)" "potential prognostic favorable (3.99e-5)" "unprognostic (2.05e-2)" "unprognostic (1.85e-2)" "unprognostic (2.88e-1)" "unprognostic (1.83e-1)" "unprognostic (6.36e-3)" "unprognostic (2.48e-3)" "unprognostic (2.45e-1)" "unprognostic (1.04e-1)" "unprognostic (1.75e-1)" "unprognostic (1.74e-2)" "potential prognostic unfavorable (5.00e-4)" "unprognostic (2.02e-1)" "unprognostic (2.58e-1)" SVIL ENSG00000197321 Supervillin O95425 10 29457338-29736959 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Desmin-related myopathy, Disease variant, Myofibrillar myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 750.5;tongue: 518.7" "Cell type enhanced" "Detected in many" "Myonuclei: 4264.9;Neutrophil progenitors: 1240.2;Neutrophils: 2215.9;Salivary myoepithelial cells: 1298.6;Smooth muscle cells: 2168.5;Thymic myoid cells: 1389.5" "Cell type enhanced" "Detected in all" "fibroblast: 948.5;vascular associated smooth muscle cell: 533.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 260.9" "Lineage enriched" "Detected in all" 9 "granulocytes: 260.9" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010878, HPA020095, HPA020138, CAB080402" Supported Supported "Plasma membrane,Actin filaments,Cytosol" NA NA 120000 "Cluster 21: Neutrophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 62: Smooth muscle cells - Muscle contraction" 26 "Plasma membrane" "Actin filaments, Cytosol" "CAB010878: , CAB080402: , HPA020095: , HPA020138: " "unprognostic (2.26e-1)" "unprognostic (1.68e-1)" "unprognostic (1.22e-1)" "unprognostic (2.17e-1)" "unprognostic (1.69e-1)" "unprognostic (6.00e-2)" "unprognostic (1.19e-1)" "unprognostic (1.40e-1)" "unprognostic (2.82e-2)" "unprognostic (1.64e-2)" "validated prognostic favorable (1.58e-5)" "validated prognostic favorable (5.65e-5)" "unprognostic (1.27e-1)" "unprognostic (1.09e-1)" "unprognostic (1.65e-1)" "unprognostic (6.08e-2)" "unprognostic (4.54e-3)" "unprognostic (1.15e-1)" "unprognostic (2.87e-1)" "unprognostic (6.60e-3)" "unprognostic (5.81e-2)" "unprognostic (7.52e-2)" "unprognostic (3.47e-2)" "unprognostic (1.35e-1)" "unprognostic (7.80e-3)" "unprognostic (5.64e-2)" "unprognostic (3.48e-1)" "unprognostic (2.86e-2)" "unprognostic (7.40e-2)" "unprognostic (6.07e-2)" "unprognostic (4.13e-1)" SVIP DKFZp313A2432 ENSG00000198168 "Small VCP interacting protein" Q8NHG7 11 22813799-22830299 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 1013.9;Epididymal principal cells: 384.6;Late primary spermatocytes: 751.6;Late spermatids: 386.4;Oocytes: 386.8;Parietal cells: 452.6;Platelets: 911.3" "Cell type enhanced" "Detected in all" "oligodendrocyte: 227.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039807 Approved NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 10 "HPA039807: " "unprognostic (8.78e-2)" "unprognostic (1.02e-1)" "unprognostic (1.07e-2)" "unprognostic (1.72e-1)" "unprognostic (2.30e-1)" "unprognostic (5.68e-2)" "unprognostic (2.97e-2)" "unprognostic (3.63e-2)" "unprognostic (6.00e-3)" "unprognostic (2.14e-3)" "potential prognostic favorable (6.47e-9)" "unprognostic (4.80e-2)" "unprognostic (3.81e-2)" "unprognostic (9.60e-2)" "unprognostic (4.60e-3)" "unprognostic (2.86e-1)" "unprognostic (8.32e-2)" "unprognostic (2.34e-2)" "unprognostic (1.62e-1)" "unprognostic (4.81e-3)" "unprognostic (1.34e-1)" "unprognostic (2.81e-1)" "unprognostic (1.38e-1)" "unprognostic (2.78e-1)" "unprognostic (1.97e-2)" "unprognostic (3.76e-2)" "unprognostic (2.81e-2)" "unprognostic (4.56e-2)" "unprognostic (1.31e-1)" "unprognostic (3.16e-1)" "unprognostic (2.60e-2)" SVOP DKFZp761H039 ENSG00000166111 "SV2 related protein" Q8N4V2 12 108907741-109021068 "Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "brain: 25.2;pituitary gland: 7.2;retina: 12.1" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 106.6;Brain inhibitory neurons: 92.7;Cone photoreceptor cells: 142.8;Early spermatids: 96.0;Gonadotrophs: 112.2;Lactotrophs: 75.2;Late spermatids: 184.8;Other brain neurons: 70.5;Retinal amacrine cells: 56.1;Retinal bipolar cells: 73.6;Retinal ganglion cells: 42.5;Retinal horizontal cells: 46.1;Rod photoreceptor cells: 107.7;Somatotrophs: 47.7;Thyrotrophs: 84.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Pancreatic Adenocarcinoma (TCGA): 1.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 4.6" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Pancreas - Alpha cells, Pancreas - Beta cells, Stomach - Gastric enteroendocrine cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016573 Uncertain NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 14: Neurons - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" 2 "HPA016573: " "unprognostic (1.51e-2)" "unprognostic (4.03e-2)" "unprognostic (4.37e-3)" SVOPL MGC46715 ENSG00000157703 "SVOP like" Q8N434 7 138594285-138701362 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 8.6;salivary gland: 5.0" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 36.9;Distal convoluted tubule cells: 90.9;Ependymal cells: 64.3;Epididymal clear cells: 47.0;Loop of henle epithelial cells: 63.3;Mast cells: 36.9;Oocytes: 165.8;Renal collecting duct intercalated cells: 183.5;Renal collecting duct principal cells: 64.1;Renal connecting tubule cells: 71.3" "Cell type enriched" "Detected in many" 6 "ependymal cell: 62.4" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 9.7" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 14 "eosinophil: 2.1" "Lineage enriched" "Detected in single" 14 "granulocytes: 2.1" "Low cancer specificity" "Detected in some" "Breast - Breast glandular cells (progenitors), Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA018035 Uncertain NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" "HPA018035: " "unprognostic (3.67e-2)" "potential prognostic favorable (1.87e-4)" "unprognostic (4.55e-2)" "unprognostic (3.00e-2)" "unprognostic (6.82e-2)" "unprognostic (4.13e-2)" "potential prognostic favorable (1.11e-4)" "unprognostic (1.11e-1)" "unprognostic (1.31e-1)" "unprognostic (6.91e-2)" "unprognostic (2.67e-1)" "unprognostic (2.83e-1)" "unprognostic (3.62e-2)" "unprognostic (9.44e-2)" SWAP70 "KIAA0640, SWAP-70" ENSG00000133789 "Switching B cell complex subunit SWAP70" Q9UH65 11 9664077-9752993 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 423.7;Extravillous trophoblasts: 274.8;Vascular endothelial cells: 322.2" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 299.4;endothelial cell: 253.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 80.5;naive B-cell: 84.7" "Group enriched" "Detected in all" 7 "B-cells: 84.7;granulocytes: 48.5;monocytes: 29.6" "Cancer enhanced" "Detected in all" "lymphoma: 134.6" "Adipose visceral - Endothelial cells, Colon - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells, Thyroid gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006810, HPA006929" Supported Supported "Plasma membrane,Actin filaments" NA NA 32000 "Cluster 29: Non-specific - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 6 "Plasma membrane" "Actin filaments" "HPA006810: , HPA006929: " "unprognostic (9.08e-2)" "unprognostic (1.12e-1)" "unprognostic (1.28e-1)" "unprognostic (3.09e-3)" "unprognostic (1.21e-1)" "unprognostic (2.92e-2)" "unprognostic (2.27e-1)" "potential prognostic unfavorable (1.73e-5)" "unprognostic (3.21e-2)" "unprognostic (1.16e-2)" "validated prognostic favorable (4.51e-8)" "validated prognostic favorable (8.08e-5)" "unprognostic (1.36e-1)" "unprognostic (7.46e-3)" "unprognostic (1.34e-1)" "unprognostic (8.14e-2)" "unprognostic (3.28e-1)" "unprognostic (1.94e-2)" "unprognostic (1.37e-1)" "unprognostic (1.90e-1)" "potential prognostic unfavorable (1.09e-4)" "unprognostic (2.34e-1)" "unprognostic (2.36e-1)" "unprognostic (7.62e-2)" "unprognostic (1.53e-2)" "unprognostic (5.11e-2)" "unprognostic (2.17e-1)" "unprognostic (3.62e-2)" "unprognostic (3.42e-1)" "unprognostic (5.84e-2)" "unprognostic (2.48e-1)" SWI5 "bA395P17.9, C9orf119, SAE3" ENSG00000175854 "SWI5 homologous recombination repair protein" 9 128275379-128316123 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 149.3" "Group enriched" "Detected in all" 4 "Early spermatids: 1340.2;Late primary spermatocytes: 678.4;Late spermatids: 1650.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pituitary gland - Somatotropes, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052032 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 41: Basophils - Unknown function" "Cluster 21: Testis - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 2 "Nucleoplasm, Cytosol" "HPA052032: " "unprognostic (6.13e-2)" "unprognostic (1.04e-2)" "unprognostic (1.05e-1)" "unprognostic (2.15e-3)" "unprognostic (5.80e-3)" "unprognostic (4.62e-3)" "unprognostic (4.63e-1)" "unprognostic (1.41e-2)" "unprognostic (6.54e-2)" "potential prognostic favorable (2.22e-4)" "unprognostic (1.23e-2)" "unprognostic (1.68e-1)" "potential prognostic unfavorable (2.43e-4)" "unprognostic (1.26e-2)" "unprognostic (1.97e-2)" "unprognostic (1.85e-1)" "unprognostic (2.43e-2)" "unprognostic (2.36e-1)" "unprognostic (1.03e-1)" "unprognostic (4.40e-2)" "unprognostic (1.85e-1)" "unprognostic (1.70e-1)" "unprognostic (1.14e-1)" "unprognostic (5.11e-2)" "unprognostic (3.25e-3)" "unprognostic (3.09e-1)" "unprognostic (2.41e-1)" "unprognostic (1.77e-1)" "unprognostic (1.17e-2)" SWSAP1 "C19orf39, FLJ35119, SWS1AP1, ZSWIM7AP1" ENSG00000173928 "SWIM-type zinc finger 7 associated protein 1" Q6NVH7 19 11374666-11376951 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 32.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052712 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 18: Adrenal cortex cells - Steroidogensis" 32 Nucleoplasm Cytosol "HPA052712: " "unprognostic (1.17e-1)" "unprognostic (2.28e-2)" "unprognostic (1.10e-1)" "unprognostic (1.26e-1)" "unprognostic (9.36e-2)" "unprognostic (1.17e-1)" "unprognostic (9.52e-2)" "unprognostic (2.83e-2)" "unprognostic (3.28e-1)" "unprognostic (7.82e-2)" "unprognostic (9.31e-2)" "potential prognostic favorable (2.20e-4)" "unprognostic (3.47e-1)" "unprognostic (1.25e-1)" "unprognostic (2.65e-1)" "unprognostic (9.27e-2)" "unprognostic (1.62e-1)" "unprognostic (6.92e-3)" "unprognostic (1.46e-2)" "unprognostic (2.78e-3)" "unprognostic (8.76e-2)" "unprognostic (1.32e-1)" "unprognostic (4.86e-1)" "unprognostic (2.03e-1)" "unprognostic (1.21e-1)" "potential prognostic favorable (1.16e-4)" "unprognostic (2.18e-1)" "unprognostic (2.19e-1)" "unprognostic (8.72e-2)" SWT1 "C1orf26, FLJ20121, HsSwt1" ENSG00000116668 "SWT1 RNA endoribonuclease homolog" Q5T5J6 1 185157080-185291781 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "testis: 35.8" "Cell type enhanced" "Detected in many" "Early spermatids: 162.6;Late primary spermatocytes: 239.8;Neutrophils: 152.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 14.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024214, HPA027334" Enhanced Approved Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 57: Testis - Spermatogenesis" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" Cytosol "HPA024214: , HPA027334: " "unprognostic (2.21e-1)" "potential prognostic unfavorable (6.22e-4)" "unprognostic (4.68e-3)" "unprognostic (2.43e-1)" "unprognostic (1.27e-1)" "unprognostic (7.79e-2)" "unprognostic (1.11e-2)" "unprognostic (3.02e-2)" "unprognostic (1.50e-2)" "validated prognostic favorable (8.00e-8)" "validated prognostic favorable (5.18e-4)" "unprognostic (2.15e-2)" "unprognostic (4.52e-2)" "unprognostic (2.35e-1)" "unprognostic (3.83e-2)" "unprognostic (1.04e-1)" "unprognostic (2.48e-1)" "unprognostic (2.81e-1)" "unprognostic (2.70e-1)" "potential prognostic unfavorable (3.53e-4)" "unprognostic (1.33e-2)" "unprognostic (1.22e-1)" "unprognostic (6.62e-2)" "unprognostic (2.11e-1)" "unprognostic (1.56e-1)" "unprognostic (4.46e-2)" "unprognostic (2.85e-1)" "unprognostic (3.83e-2)" "unprognostic (4.16e-2)" "unprognostic (3.01e-2)" SYAP1 "FLJ14495, PRO3113" ENSG00000169895 "Synapse associated protein 1" Q96A49 X 16719612-16765340 "Predicted intracellular proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Mast cells: 832.0;Neutrophils: 2222.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000175, HPA000882, HPA048047" Approved Enhanced "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 11000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 36: Non-specific - mRNA processing" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 21 "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA000175: , HPA000882: , HPA048047: " "unprognostic (2.47e-1)" "unprognostic (5.26e-3)" "unprognostic (2.60e-2)" "unprognostic (8.32e-3)" "unprognostic (1.60e-3)" "unprognostic (1.58e-1)" "unprognostic (5.46e-1)" "potential prognostic unfavorable (2.13e-5)" "potential prognostic unfavorable (7.89e-4)" "unprognostic (2.39e-3)" "unprognostic (4.56e-3)" "unprognostic (5.93e-3)" "unprognostic (5.01e-2)" "unprognostic (7.90e-2)" "unprognostic (4.39e-2)" "unprognostic (1.53e-2)" "unprognostic (6.43e-2)" "unprognostic (1.58e-1)" "unprognostic (1.03e-1)" "unprognostic (2.83e-2)" "unprognostic (2.59e-1)" "unprognostic (1.11e-1)" "unprognostic (1.40e-1)" "unprognostic (8.78e-2)" "unprognostic (2.17e-1)" "unprognostic (2.26e-1)" "unprognostic (1.98e-1)" "unprognostic (1.62e-2)" "unprognostic (1.57e-2)" "unprognostic (5.38e-2)" "unprognostic (5.88e-3)" SYBU "FLJ20366, GOLSYN, KIAA1472, OCSYN, SNPHL" ENSG00000147642 Syntabulin Q9NX95 8 109573978-109691791 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 92.9;pancreas: 132.5" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 254.7;Brain inhibitory neurons: 237.8;Lactotrophs: 414.9;Other brain neurons: 229.7;Retinal horizontal cells: 222.4;Thyrotrophs: 235.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 21 "memory B-cell: 6.5;naive B-cell: 3.2" "Lineage enriched" "Detected in single" 27 "B-cells: 6.5" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053057 Uncertain Supported Vesicles NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 70: Non-specific - Protein processing" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 6 Vesicles "HPA053057: " "unprognostic (1.19e-1)" "unprognostic (2.03e-1)" "unprognostic (1.23e-1)" "unprognostic (1.24e-1)" "unprognostic (2.66e-1)" "unprognostic (1.16e-1)" "unprognostic (9.39e-2)" "unprognostic (2.00e-2)" "unprognostic (8.55e-2)" "unprognostic (1.86e-1)" "unprognostic (1.05e-2)" "unprognostic (3.52e-3)" "unprognostic (3.42e-3)" "unprognostic (1.25e-3)" "unprognostic (3.63e-1)" "unprognostic (2.52e-1)" "unprognostic (1.65e-1)" "unprognostic (5.62e-2)" "unprognostic (7.60e-2)" "unprognostic (2.27e-2)" "unprognostic (1.36e-1)" "unprognostic (2.05e-1)" "unprognostic (1.59e-2)" "unprognostic (8.71e-2)" "unprognostic (6.17e-2)" "unprognostic (2.74e-1)" "unprognostic (1.58e-1)" "unprognostic (2.47e-1)" "unprognostic (1.11e-1)" "unprognostic (6.65e-2)" "unprognostic (9.65e-2)" SYCE1 "bA108K14.6, C10orf94, CT76" ENSG00000171772 "Synaptonemal complex central element protein 1" Q8N0S2 10 133553901-133569835 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Meiosis" "Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 17.7;testis: 69.5" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 136.9;Early primary spermatocytes: 511.1;Early spermatids: 121.4;Late primary spermatocytes: 262.2;Late spermatids: 131.3;Oocytes: 50.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 23.4" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA040208 Enhanced Approved Nucleoplasm,Vesicles,Cytosol No No "Cluster 30: Non-specific - DNA binding" "Cluster 67: Testis - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 3: Early primary spermatocytes - Early meiosis" 48 Nucleoplasm "Vesicles, Cytosol" "HPA040208: " "unprognostic (1.38e-2)" "unprognostic (8.47e-2)" "unprognostic (6.39e-3)" "unprognostic (2.83e-1)" "unprognostic (1.56e-1)" "unprognostic (1.02e-2)" "unprognostic (2.30e-1)" "unprognostic (1.80e-2)" "unprognostic (2.63e-1)" "unprognostic (2.55e-2)" "unprognostic (1.68e-1)" "unprognostic (5.23e-1)" "unprognostic (7.09e-2)" "unprognostic (1.34e-1)" "unprognostic (2.53e-1)" "unprognostic (1.22e-2)" SYCE1L MRP2 ENSG00000205078 "Synaptonemal complex central element protein 1 like" A8MT33 16 77199408-77213215 "Predicted intracellular proteins" Meiosis "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 17.8" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 60.3;Breast secretory cells: 167.9;Enteric transient amplifying cells: 70.4;Epididymal efferent duct absorptive cells: 71.0;Late spermatids: 86.3;Paneth cells: 112.2" "Cell type enhanced" "Detected in many" "CGE interneuron: 22.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA062464, HPA066691" Approved "Intermediate filaments" No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 21: Testis - Mixed function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 15: Non-specific - Protein processing" "Intermediate filaments" "HPA062464: , HPA066691: " "unprognostic (5.83e-2)" "unprognostic (2.98e-2)" "unprognostic (1.48e-1)" "unprognostic (1.03e-1)" "unprognostic (2.65e-2)" "unprognostic (2.92e-2)" "unprognostic (1.40e-1)" "unprognostic (3.48e-2)" "unprognostic (1.09e-1)" "unprognostic (3.89e-2)" "validated prognostic unfavorable (3.40e-8)" "validated prognostic unfavorable (3.48e-4)" "unprognostic (3.69e-2)" "unprognostic (4.98e-2)" "unprognostic (5.54e-3)" "unprognostic (4.19e-3)" "unprognostic (1.60e-1)" "unprognostic (2.29e-1)" "unprognostic (2.25e-2)" "unprognostic (5.25e-3)" "unprognostic (7.14e-2)" "unprognostic (1.89e-1)" "unprognostic (3.64e-2)" "unprognostic (1.58e-1)" "unprognostic (1.18e-2)" "unprognostic (4.40e-1)" "unprognostic (8.97e-2)" "unprognostic (9.08e-2)" SYCE2 CESC1 ENSG00000161860 "Synaptonemal complex central element protein 2" Q6PIF2 19 12898786-12919293 "Predicted intracellular proteins" "Cell cycle, Cell division, Meiosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 25.3" "Group enriched" "Detected in many" 4 "Early primary spermatocytes: 417.4;Late primary spermatocytes: 118.1" "Cell type enhanced" "Detected in all" "Bergmann glia: 30.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 2.7" "Lineage enhanced" "Detected in single" "NK-cells: 2.7" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA042080, HPA062919" Enhanced Supported Nucleoplasm NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 67: Testis - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 3: Early primary spermatocytes - Early meiosis" 13 Nucleoplasm "HPA042080: , HPA062919: " "unprognostic (1.97e-2)" "unprognostic (1.27e-1)" "unprognostic (1.67e-1)" "potential prognostic favorable (2.21e-5)" "unprognostic (5.70e-2)" "unprognostic (3.38e-1)" "unprognostic (1.59e-1)" "unprognostic (7.09e-2)" "unprognostic (2.73e-2)" "unprognostic (4.89e-2)" "unprognostic (1.57e-2)" "unprognostic (1.32e-3)" "unprognostic (4.60e-2)" "unprognostic (3.99e-2)" "unprognostic (3.15e-1)" "unprognostic (1.14e-1)" "unprognostic (1.52e-1)" "unprognostic (9.39e-3)" "unprognostic (1.42e-3)" "unprognostic (2.01e-1)" "unprognostic (1.68e-1)" SYCE3 C22orf41 ENSG00000217442 "Synaptonemal complex central element protein 3" A1L190 22 50551112-50562919 "Predicted intracellular proteins" "Cell cycle, Cell division, Meiosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 53 "testis: 133.4" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 145.2;Early primary spermatocytes: 397.8;Early spermatids: 440.6;Late primary spermatocytes: 877.3;Late spermatids: 66.1" "Cell type enhanced" "Detected in some" "Bergmann glia: 1.9;lower rhombic lip: 1.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "neutrophil: 4.4" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in many" 5 "prostate cancer: 12.9" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA047813 Approved "Nucleoplasm,Nucleoli,Golgi apparatus" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 19: Astrocytes - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 13 "Nucleoplasm, Nucleoli, Golgi apparatus" "HPA047813: " "unprognostic (1.22e-2)" "unprognostic (2.68e-2)" "unprognostic (4.21e-2)" "unprognostic (1.09e-1)" "unprognostic (1.67e-2)" "unprognostic (4.38e-2)" "unprognostic (3.11e-2)" "unprognostic (1.07e-1)" "unprognostic (3.38e-1)" "unprognostic (2.02e-2)" "unprognostic (1.32e-1)" "unprognostic (9.23e-2)" "unprognostic (3.29e-1)" "unprognostic (1.64e-1)" "unprognostic (5.15e-2)" "unprognostic (8.14e-2)" "unprognostic (1.95e-1)" "unprognostic (3.60e-2)" "unprognostic (3.41e-2)" "unprognostic (2.81e-3)" "unprognostic (2.65e-1)" "unprognostic (2.88e-2)" "unprognostic (1.23e-1)" "unprognostic (3.85e-1)" SYCN "FLJ27441, INSSA1, SYL" ENSG00000179751 Syncollin Q0VAF6 19 39202825-39204263 "Predicted intracellular proteins" Exocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 964 "pancreas: 26730.7" "Cell type enriched" "Detected in some" 238 "Pancreatic acinar cells: 15151.8" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 845 "Pancreatic Adenocarcinoma (TCGA): 544.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Exocrine glandular cells, Testis - Sertoli cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA047654 Enhanced "Intracellular and membrane" Other NA NA 500000 "Cluster 8: Pancreas - Proteolysis" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 5: Pancreatic acinar cells - Pancreatic exocrine secretion" 2 "HPA047654: " "unprognostic (8.03e-2)" "unprognostic (4.90e-2)" SYCP1 "CT8, HOM-TES-14, SCP1" ENSG00000198765 "Synaptonemal complex protein 1" Q15431 1 114854863-114995370 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Meiosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 70 "testis: 37.6" "Cell type enriched" "Detected in some" 5 "Early primary spermatocytes: 1365.5" "Cell type enriched" "Detected in single" 5 "thalamic excitatory: 4.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 155 "Bone cancer: 21.5" "Minor Salivary Gland - Minor salivary glandular cells, Skin - Eccrine sweat gland cells, Testis - Spermatocytes" "Region enriched" "Detected in single" 51 "cerebellum: 14.7" "Not detected" "Not detected" HPA021083 Enhanced Approved "Nuclear bodies,Cytosol" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 3: Early primary spermatocytes - Early meiosis" 1 "Nuclear bodies, Cytosol" "HPA021083: " "unprognostic (7.23e-3)" SYCP2 SCP2 ENSG00000196074 "Synaptonemal complex protein 2" Q9BX26 20 59863564-59933655 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Meiosis" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "breast: 13.0;testis: 40.2" "Cell type enhanced" "Detected in many" "Bergmann glia: 73.4;Early primary spermatocytes: 515.3;Late primary spermatocytes: 320.4;Neutrophils: 88.6;Oocytes: 142.8" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Breast Invasive Carcinoma (TCGA): 20.1;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 32.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 38.4" "Colon - Enteric glia cells, Minor Salivary Gland - Smooth muscle cells, Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA065613 Approved Nucleoplasm NA NA "Cluster 41: Basophils - Unknown function" "Cluster 57: Testis - Spermatogenesis" "Cluster 2: Neurons - Nucleosome" "Cluster 27: Breast cancer - Unknown function" "Cluster 3: Early primary spermatocytes - Early meiosis" 1 Nucleoplasm "HPA065613: " "unprognostic (5.29e-2)" "unprognostic (9.47e-3)" "unprognostic (3.05e-2)" "unprognostic (5.00e-3)" "unprognostic (3.56e-2)" "unprognostic (1.70e-2)" "unprognostic (1.66e-1)" "unprognostic (1.22e-1)" "unprognostic (6.30e-3)" "unprognostic (9.65e-2)" "unprognostic (9.72e-3)" "unprognostic (2.26e-1)" "unprognostic (1.76e-1)" "unprognostic (1.48e-1)" "unprognostic (2.91e-1)" "unprognostic (1.10e-1)" "unprognostic (1.90e-1)" "unprognostic (3.82e-1)" "unprognostic (3.36e-1)" "unprognostic (1.36e-3)" "unprognostic (1.79e-2)" "unprognostic (1.87e-2)" "unprognostic (1.26e-1)" "unprognostic (1.63e-1)" "unprognostic (1.69e-1)" "unprognostic (2.76e-3)" SYCP2L "C6orf177, dJ62D2.1, NO145" ENSG00000153157 "Synaptonemal complex protein 2 like" Q5T4T6 6 10886831-10979320 "Predicted intracellular proteins" "Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "parathyroid gland: 64.6" "Cell type enhanced" "Detected in many" "Epicardial cells: 129.6;Late primary spermatocytes: 29.3;Mast cells: 60.4;Oocytes: 92.1;pDCs: 53.9;Undifferentiated spermatogonia: 29.5" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 2.8" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 7 "basophil: 1.7;eosinophil: 3.4;plasmacytoid DC: 4.2" "Group enriched" "Detected in many" 17 "dendritic cells: 4.2;granulocytes: 3.4" "Cancer enhanced" "Detected in some" "Leukemia: 6.6;testis cancer: 7.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA034679 Supported Nucleoplasm NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 49: HMC-1 - Innate immune response" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" Nucleoplasm "HPA034679: " "unprognostic (1.22e-1)" "unprognostic (2.85e-3)" "unprognostic (4.46e-2)" "unprognostic (3.41e-1)" "unprognostic (3.92e-1)" "unprognostic (2.55e-1)" SYCP3 ENSG00000139351 "Synaptonemal complex protein 3" Q8IZU3 12 101728648-101739472 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Meiosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 110 "testis: 77.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 666.7;Differentiating spermatogonia: 192.8;Early primary spermatocytes: 995.5;Late primary spermatocytes: 283.0;Oocytes: 377.6" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in single" 142 "Testicular Germ Cell Tumor (TCGA): 29.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 22 "Myeloma: 7.4" "Testis - Spermatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB032978, HPA039635, HPA043938" Enhanced NA NA "Cluster 32: Basophils - Transcription" "Cluster 57: Testis - Spermatogenesis" "Cluster 15: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 3: Early primary spermatocytes - Early meiosis" 5 "CAB032978: , HPA039635: , HPA043938: " "unprognostic (2.68e-1)" "unprognostic (3.84e-2)" "unprognostic (2.29e-1)" SYDE1 "7h3, FLJ13511, SYD1" ENSG00000105137 "Synapse defective Rho GTPase homolog 1" Q6ZW31 19 15107401-15114985 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Extravillous trophoblasts: 216.3;Syncytiotrophoblasts: 194.8" "Cell type enhanced" "Detected in some" "fibroblast: 23.3;pericyte: 66.2;vascular associated smooth muscle cell: 25.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013328 Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 72: Neuronal - Signal transduction" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." 6 Nucleoplasm "Golgi apparatus, Cytosol" "HPA013328: " "unprognostic (5.43e-1)" "unprognostic (4.39e-2)" "unprognostic (1.51e-1)" "potential prognostic unfavorable (1.52e-4)" "unprognostic (6.66e-3)" "unprognostic (5.18e-2)" "unprognostic (8.56e-2)" "unprognostic (3.45e-3)" "unprognostic (1.63e-1)" "unprognostic (2.57e-2)" "unprognostic (1.82e-2)" "unprognostic (1.63e-1)" "unprognostic (1.68e-1)" "unprognostic (1.36e-1)" "unprognostic (8.42e-2)" "unprognostic (1.03e-1)" "potential prognostic unfavorable (4.48e-4)" "unprognostic (6.44e-2)" "unprognostic (2.95e-1)" "unprognostic (8.43e-3)" "unprognostic (1.00e-1)" "unprognostic (1.25e-1)" "unprognostic (1.44e-1)" "unprognostic (1.23e-1)" "unprognostic (3.35e-1)" "unprognostic (1.45e-1)" "unprognostic (1.44e-2)" "unprognostic (9.20e-3)" "unprognostic (8.89e-2)" "unprognostic (4.87e-2)" "unprognostic (1.25e-1)" SYDE2 FLJ13815 ENSG00000097096 "Synapse defective Rho GTPase homolog 2" Q5VT97 1 85156889-85201724 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 7.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 76.7;Cardiomyocytes: 136.7;Corticotrophs: 86.2;Pituicytes/FSCs: 66.9;Retinal pigment epithelial cells: 72.5;Rod photoreceptor cells: 194.6" "Cell type enhanced" "Detected in many" "hippocampal dentate gyrus: 53.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027138, HPA058378" Uncertain Approved "Nucleoli,Nucleoli rim,Golgi apparatus" No No "Cluster 42: Retina - Visual perception" "Cluster 29: Forebrain - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" 13 "Nucleoli, Nucleoli rim, Golgi apparatus" "HPA027138: , HPA058378: " "potential prognostic favorable (2.04e-4)" "unprognostic (1.02e-1)" "unprognostic (2.69e-1)" "unprognostic (6.45e-2)" "unprognostic (1.38e-2)" "unprognostic (2.59e-1)" "validated prognostic favorable (9.67e-8)" "validated prognostic favorable (8.90e-4)" "unprognostic (2.67e-1)" "unprognostic (8.09e-3)" "unprognostic (4.65e-2)" "unprognostic (1.97e-2)" "unprognostic (1.35e-2)" "unprognostic (1.05e-1)" "unprognostic (5.10e-1)" "unprognostic (1.52e-1)" "unprognostic (1.69e-2)" "unprognostic (4.68e-2)" "unprognostic (1.42e-1)" "unprognostic (1.88e-1)" "unprognostic (6.86e-2)" SYF2 "CBPIN, DKFZp564O2082, fSAP29, NTC31, p29" ENSG00000117614 "SYF2 pre-mRNA splicing factor" O95926 1 25222276-25232502 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018265, HPA070710" Approved Supported "Nuclear speckles" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 54: Non-specific - Ribosome" "Cluster 55: Non-specific - Transcription" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 36 "Nuclear speckles" "HPA018265: , HPA070710: " "unprognostic (5.55e-3)" "unprognostic (1.33e-1)" "unprognostic (3.78e-2)" "unprognostic (2.96e-1)" "unprognostic (2.54e-1)" "unprognostic (2.21e-2)" "unprognostic (2.26e-2)" "unprognostic (3.51e-2)" "unprognostic (8.42e-2)" "potential prognostic unfavorable (6.11e-4)" "validated prognostic favorable (1.09e-7)" "validated prognostic favorable (8.20e-4)" "unprognostic (8.43e-2)" "potential prognostic unfavorable (4.95e-4)" "unprognostic (1.11e-3)" "unprognostic (2.87e-2)" "unprognostic (2.32e-1)" "unprognostic (2.22e-2)" "unprognostic (2.27e-1)" "unprognostic (8.36e-3)" "unprognostic (4.71e-3)" "potential prognostic unfavorable (9.70e-4)" "unprognostic (1.17e-1)" "unprognostic (4.24e-1)" "unprognostic (2.05e-1)" "unprognostic (2.33e-2)" "unprognostic (1.88e-2)" "unprognostic (1.47e-1)" "unprognostic (1.35e-1)" "unprognostic (8.44e-2)" "potential prognostic favorable (7.94e-4)" SYK ENSG00000165025 "Spleen associated tyrosine kinase" P43405 9 90801787-90898549 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "Adaptive immunity, Angiogenesis, Host-virus interaction, Immunity, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 69.1;parathyroid gland: 82.3" "Cell type enhanced" "Detected in many" "B-cells: 321.9;cDC: 311.6;Macrophages: 326.0;Microglia: 686.5;Monocyte progenitors: 604.3;monocytes: 415.3;Neutrophil progenitors: 1148.4;Neutrophils: 861.4;pDCs: 312.8" "Cell type enriched" "Detected in many" 9 "central nervous system macrophage: 863.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 13 "classical monocyte: 77.3;eosinophil: 83.6;intermediate monocyte: 64.0;memory B-cell: 74.7;myeloid DC: 85.1;naive B-cell: 58.6;neutrophil: 112.4;NK-cell: 30.2;non-classical monocyte: 60.5;plasmacytoid DC: 63.3" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "lymphoma: 87.6" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Heart muscle - Macrophages, Lung - Macrophages, Skeletal muscle - Macrophages, Spleen - B-cells (Spleen), Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA001384, CAB007773" Enhanced Approved "Vesicles,Plasma membrane,Cytosol" No NA 130000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 64 "Plasma membrane, Cytosol" Vesicles "CAB007773: , HPA001384: " "unprognostic (6.27e-2)" "unprognostic (2.37e-2)" "unprognostic (4.53e-1)" "unprognostic (5.02e-2)" "unprognostic (2.18e-1)" "unprognostic (2.01e-1)" "unprognostic (1.65e-1)" "unprognostic (2.28e-1)" "unprognostic (6.54e-2)" "unprognostic (2.96e-1)" "unprognostic (5.34e-3)" "unprognostic (1.63e-1)" "unprognostic (6.25e-2)" "unprognostic (1.47e-1)" "unprognostic (2.07e-1)" "unprognostic (2.39e-2)" "unprognostic (7.45e-2)" "unprognostic (6.36e-2)" "unprognostic (2.53e-1)" "unprognostic (6.92e-2)" "unprognostic (5.50e-2)" "unprognostic (4.90e-2)" "unprognostic (1.88e-3)" "unprognostic (2.17e-1)" "unprognostic (5.82e-2)" "unprognostic (3.26e-1)" "unprognostic (2.47e-3)" "unprognostic (1.77e-1)" "unprognostic (2.77e-2)" "unprognostic (1.50e-2)" "unprognostic (1.13e-2)" SYMPK "Pta1, SPK, SYM" ENSG00000125755 "Symplekin scaffold protein" Q92797 19 45815410-45863194 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, mRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 227.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041756, HPA042449" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 67: Testis - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 82: Dendritic cells - Antigen presentation" 54 Nucleoplasm "Plasma membrane, Cytosol" "HPA041756: , HPA042449: " "unprognostic (1.19e-2)" "unprognostic (1.16e-1)" "unprognostic (1.58e-1)" "unprognostic (1.83e-2)" "unprognostic (2.05e-1)" "unprognostic (5.39e-2)" "unprognostic (2.46e-2)" "unprognostic (1.57e-2)" "unprognostic (1.11e-1)" "unprognostic (2.09e-1)" "potential prognostic favorable (3.90e-4)" "unprognostic (1.17e-2)" "unprognostic (1.17e-1)" "potential prognostic unfavorable (8.09e-4)" "unprognostic (1.43e-1)" "potential prognostic unfavorable (8.35e-5)" "unprognostic (3.21e-1)" "unprognostic (2.23e-1)" "unprognostic (5.56e-2)" "unprognostic (1.18e-2)" "unprognostic (1.40e-1)" "unprognostic (7.79e-2)" "unprognostic (1.05e-1)" "unprognostic (3.21e-1)" "unprognostic (6.16e-3)" "unprognostic (3.04e-1)" "unprognostic (3.96e-2)" "unprognostic (1.35e-1)" "unprognostic (1.94e-1)" "unprognostic (4.25e-2)" "unprognostic (1.61e-1)" SYN1 MRX50 ENSG00000008056 "Synapsin I" P17600 X 47571901-47619857 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 311.6" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 57.5;Brain inhibitory neurons: 52.4;Oligodendrocyte progenitor cells: 13.2;Other brain neurons: 51.6;Pancreatic islet cells: 14.7;Retinal amacrine cells: 16.5;Retinal bipolar cells: 15.1;Retinal horizontal cells: 12.0" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 5 "Glioblastoma Multiforme (TCGA): 30.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 8.4;Neuroblastoma: 10.1" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Pituitary gland - Lactotropes, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000397, CAB021929" Enhanced NA NA 560000 "Cluster 10: Brain - Synaptic signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 8 "CAB021929: , HPA000397: " "unprognostic (1.00e-1)" "unprognostic (2.30e-1)" "unprognostic (3.19e-2)" "unprognostic (1.50e-2)" "unprognostic (8.42e-3)" "unprognostic (6.67e-2)" "unprognostic (1.03e-2)" "unprognostic (3.69e-2)" "unprognostic (3.06e-2)" "unprognostic (4.39e-2)" "unprognostic (2.07e-2)" "unprognostic (3.12e-1)" "unprognostic (6.74e-2)" "unprognostic (6.58e-2)" "unprognostic (3.10e-1)" "unprognostic (2.86e-1)" "unprognostic (1.50e-2)" "unprognostic (1.75e-1)" "unprognostic (3.74e-2)" "unprognostic (1.47e-1)" "unprognostic (9.66e-3)" "unprognostic (1.17e-1)" "unprognostic (4.05e-2)" "unprognostic (2.29e-3)" "unprognostic (1.83e-1)" "potential prognostic unfavorable (7.64e-4)" "unprognostic (2.37e-1)" "unprognostic (2.48e-2)" "unprognostic (8.84e-3)" SYN2 "SYNII, SYNIIa, SYNIIb" ENSG00000157152 "Synapsin II" Q92777 3 12004388-12192032 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Schizophrenia "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "brain: 119.7" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 477.9;Brain inhibitory neurons: 564.7;Cone photoreceptor cells: 144.9;Early primary spermatocytes: 153.0;Lactotrophs: 185.5;Oligodendrocyte progenitor cells: 181.6;Other brain neurons: 253.7;Pituitary stem cells: 145.3;Retinal amacrine cells: 163.4;Retinal bipolar cells: 196.7;Retinal ganglion cells: 726.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 7.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "cervical cancer: 5.9;Neuroblastoma: 20.5" "Colon - Colon enteroendocrine cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Pituitary gland - Lactotropes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037012, CAB079005" Supported Approved Nucleoplasm NA NA 22000 "Cluster 73: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" 8 Nucleoplasm "CAB079005: , HPA037012: " "unprognostic (1.48e-1)" "unprognostic (1.82e-1)" "unprognostic (6.06e-2)" "unprognostic (3.16e-2)" "unprognostic (1.02e-1)" "potential prognostic unfavorable (3.27e-4)" "unprognostic (3.98e-1)" SYN3 ENSG00000185666 "Synapsin III" O14994 22 32507820-33058381 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.0" "Cell type enhanced" "Detected in many" "Adipocytes: 430.5;Brain excitatory neurons: 369.4;Brain inhibitory neurons: 557.8;Cardiomyocytes: 977.1;Corticotrophs: 362.6;Epicardial cells: 657.2;Fibroblasts: 376.7;Late spermatids: 510.6;Other brain neurons: 365.5;Pericytes: 523.1;Retinal ganglion cells: 1286.3;Thyrotrophs: 769.4" "Cell type enhanced" "Detected in all" "cerebellar inhibitory: 1835.7" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 22.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 3.2" "Group enriched" "Detected in many" 11 "B-cells: 3.2;granulocytes: 1.6" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034566 Uncertain NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 3 "HPA034566: " "unprognostic (2.62e-1)" "unprognostic (1.94e-2)" "unprognostic (7.36e-2)" "unprognostic (8.38e-3)" "unprognostic (6.48e-2)" "unprognostic (2.86e-2)" "potential prognostic favorable (1.35e-4)" "unprognostic (6.13e-2)" "unprognostic (1.01e-2)" "unprognostic (5.84e-2)" "unprognostic (2.09e-1)" "unprognostic (9.40e-3)" "unprognostic (5.11e-3)" "unprognostic (1.48e-1)" "unprognostic (1.53e-2)" "unprognostic (1.75e-2)" "unprognostic (1.30e-3)" "unprognostic (5.64e-2)" "unprognostic (3.25e-1)" "unprognostic (2.65e-1)" "unprognostic (5.23e-2)" SYNC "SYNC1, SYNCOILIN" ENSG00000162520 "Syncoilin, intermediate filament protein" Q9H7C4 1 32679906-32703596 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 100.1;tongue: 68.5" "Cell type enhanced" "Detected in many" "Myonuclei: 145.7;Thymic myoid cells: 157.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Kidney - Fibroblasts, Prostate - Smooth muscle cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA028311, HPA063549" Enhanced Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 13 "Plasma membrane" "Golgi apparatus, Vesicles" "HPA028311: , HPA063549: " "unprognostic (5.49e-2)" "unprognostic (1.10e-1)" "unprognostic (3.30e-1)" "unprognostic (1.21e-2)" "unprognostic (2.47e-1)" "unprognostic (2.23e-1)" "unprognostic (7.14e-2)" "potential prognostic unfavorable (2.10e-4)" "unprognostic (7.26e-2)" "unprognostic (4.01e-2)" "potential prognostic unfavorable (8.01e-4)" "unprognostic (2.28e-2)" "unprognostic (9.00e-2)" "potential prognostic unfavorable (3.77e-5)" "unprognostic (5.30e-3)" "unprognostic (9.13e-3)" "unprognostic (3.88e-1)" "unprognostic (1.76e-2)" "unprognostic (2.41e-1)" "unprognostic (1.83e-1)" "unprognostic (4.17e-2)" "unprognostic (5.37e-3)" "unprognostic (1.16e-1)" "unprognostic (2.90e-1)" "unprognostic (9.07e-3)" "unprognostic (2.93e-2)" "unprognostic (1.45e-2)" "unprognostic (8.85e-2)" "unprognostic (7.08e-2)" "potential prognostic favorable (3.15e-5)" "unprognostic (2.24e-1)" SYNCRIP "dJ3J17.2, GRY-RBP, hnRNP-Q, HNRNPQ, HNRPQ1, NSAP1" ENSG00000135316 "Synaptotagmin binding cytoplasmic RNA interacting protein" O60506 6 85607779-85644063 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing, Translation regulation" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 32.8;Bergmann glia: 42.8;Brain excitatory neurons: 36.8;Brain inhibitory neurons: 35.4;Choroid plexus epithelial cells: 50.0;Distal convoluted tubule cells: 51.4;Ependymal cells: 32.7;Loop of henle epithelial cells: 44.4;Microglia: 74.4;Oligodendrocyte progenitor cells: 44.7;Oligodendrocytes: 50.2;Other brain neurons: 32.5;Papillary tip epithelial cells: 41.8;Podocytes: 34.3;Proximal tubule cells: 54.1;Renal collecting duct intercalated cells: 49.1;Renal collecting duct principal cells: 40.1;Renal connecting tubule cells: 50.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010895, HPA041275, HPA069241" Supported Uncertain Nucleoplasm,Vesicles,Cytosol NA NA 840000 "Cluster 33: Non-specific - ATP binding" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 102: Non-specific - Mixed function" 148 Nucleoplasm "Vesicles, Cytosol" "CAB010895: , HPA041275: , HPA069241: " "unprognostic (1.38e-1)" "unprognostic (2.07e-2)" "unprognostic (2.02e-3)" "unprognostic (2.57e-3)" "unprognostic (2.96e-2)" "unprognostic (2.43e-1)" "unprognostic (1.48e-2)" "unprognostic (3.39e-2)" "unprognostic (8.75e-2)" "unprognostic (1.25e-2)" "potential prognostic favorable (8.43e-7)" "unprognostic (4.92e-3)" "unprognostic (3.72e-1)" "potential prognostic unfavorable (3.53e-5)" "unprognostic (3.18e-2)" "unprognostic (5.14e-3)" "unprognostic (6.81e-3)" "unprognostic (3.67e-1)" "unprognostic (2.76e-2)" "unprognostic (3.83e-2)" "potential prognostic unfavorable (1.99e-4)" "unprognostic (4.33e-3)" "unprognostic (1.21e-3)" "unprognostic (9.11e-2)" "unprognostic (3.78e-2)" "unprognostic (1.27e-1)" "unprognostic (9.26e-2)" "unprognostic (9.16e-2)" "unprognostic (9.52e-2)" "unprognostic (2.01e-1)" "unprognostic (7.65e-2)" SYNDIG1 "C20orf39, DSPC2, FLJ14220, IFITMD5, TMEM90B" ENSG00000101463 "Synapse differentiation inducing 1" Q9H7V2 20 24469629-24666616 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 44.8;heart muscle: 26.1" "Cell type enriched" "Detected in many" 8 "Microglia: 2387.0" "Cell type enriched" "Detected in all" 7 "central nervous system macrophage: 2747.7" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 23.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 6.3;Sarcoma: 6.6" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044271, HPA059267" Enhanced Vesicles NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 30: White matter - Myelination" "Cluster 1: Neuronal - Visual perception" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 14 Vesicles "HPA044271: , HPA059267: " "unprognostic (1.16e-1)" "unprognostic (3.70e-1)" "unprognostic (2.76e-2)" "unprognostic (1.79e-1)" "unprognostic (1.93e-2)" "unprognostic (6.99e-3)" "unprognostic (1.13e-1)" "unprognostic (6.73e-2)" "unprognostic (3.58e-2)" "unprognostic (1.31e-1)" "unprognostic (1.07e-1)" "unprognostic (7.88e-2)" "unprognostic (1.67e-2)" "unprognostic (1.55e-1)" "unprognostic (2.84e-1)" "unprognostic (3.19e-1)" "unprognostic (1.97e-1)" "unprognostic (4.58e-1)" "unprognostic (2.60e-1)" "unprognostic (9.50e-2)" "unprognostic (4.01e-2)" "unprognostic (1.23e-2)" "unprognostic (3.52e-2)" "unprognostic (1.97e-1)" "potential prognostic unfavorable (2.24e-7)" "unprognostic (7.50e-2)" SYNDIG1L "capucin, DSPC1, IFITMD4, TMEM90A" ENSG00000183379 "Synapse differentiation inducing 1 like" A6NDD5 14 74405894-74426210 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 47 "brain: 488.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 21.1;Brain inhibitory neurons: 50.3;Epididymal principal cells: 4.9;Retinal amacrine cells: 16.0;Retinal bipolar cells: 12.5" "Group enriched" "Detected in many" 4 "eccentric medium spiny neuron: 34.2;medium spiny neuron: 105.5;midbrain-derived inhibitory: 121.5" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in all" 5 "basal ganglia: 991.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Alveolar cells type 2" "Region enriched" "Detected in all" 8 "basal ganglia: 280.8" "Region enriched" "Detected in many" 7 "basal ganglia: 164.1" "HPA042594, HPA048487" Uncertain Uncertain Cytosol NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 35: Neurons - Synaptic function & neurogenesis" Cytosol "HPA042594: , HPA048487: " "unprognostic (6.45e-2)" "unprognostic (3.64e-1)" "unprognostic (3.00e-2)" SYNE1 "8B, ARCA1, C6orf98, CPG2, dJ45H2.2, enaptin, KIAA0796, MYNE1, Nesp1, Nesprin-1, SCAR8, SYNE-1B" ENSG00000131018 "Spectrin repeat containing nuclear envelope protein 1" Q8NF91 6 152121687-152637801 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Spermatogenesis" Actin-binding "Cancer-related genes, Disease variant, Emery-Dreifuss muscular dystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 2727.9;Ependymal cells: 2334.2;Epicardial cells: 1614.6;Neutrophil progenitors: 2087.1;Neutrophils: 2250.0;Sertoli cells: 1317.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 56.6" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Prostate - Fibroblasts, Spleen - Endothelial cells" "Low region specificity" "Detected in all" HPA019113 Approved Supported "Nucleoplasm,Nuclear membrane" NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 11 "Nucleoplasm, Nuclear membrane" "HPA019113: " "unprognostic (1.41e-2)" "unprognostic (9.46e-3)" "unprognostic (5.63e-2)" "unprognostic (4.11e-1)" "unprognostic (2.41e-2)" "unprognostic (1.26e-1)" "unprognostic (1.39e-1)" "unprognostic (9.90e-2)" "unprognostic (1.17e-1)" "unprognostic (1.06e-1)" "unprognostic (3.87e-2)" "unprognostic (3.59e-2)" "unprognostic (3.88e-3)" "unprognostic (1.10e-1)" "potential prognostic favorable (8.34e-4)" "unprognostic (5.07e-3)" "unprognostic (1.32e-1)" "unprognostic (3.20e-1)" "unprognostic (8.94e-2)" "unprognostic (9.35e-2)" "unprognostic (9.70e-3)" "unprognostic (3.00e-3)" "unprognostic (3.10e-2)" "unprognostic (1.79e-1)" "unprognostic (4.72e-2)" "unprognostic (5.71e-3)" "unprognostic (8.18e-2)" "unprognostic (1.31e-2)" "unprognostic (1.43e-1)" "unprognostic (1.25e-1)" "unprognostic (9.14e-2)" SYNE2 "DKFZP434H2235, KIAA1011, Nesp2, Nesprin-2, NUA, NUANCE, SYNE-2" ENSG00000054654 "Spectrin repeat containing nuclear envelope protein 2" Q8WXH0 14 63761899-64226433 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Actin-binding "Disease variant, Emery-Dreifuss muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 185.6" "Cell type enhanced" "Detected in many" "Neutrophils: 1744.6;Proximal tubule cells: 2203.1;Sertoli cells: 2034.3" "Group enriched" "Detected in all" 4 "choroid plexus epithelial cell: 681.4;endothelial cell: 707.3;ependymal cell: 182.9;fibroblast: 260.4;leukocyte: 689.5;pericyte: 517.6;vascular associated smooth muscle cell: 665.2" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "choroid plexus: 187.6" "Immune cell enhanced" "Detected in many" "eosinophil: 73.9" "Group enriched" "Detected in many" 11 "granulocytes: 73.9;T-cells: 38.6" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003435, HPA050204" Enhanced Approved "Nuclear membrane,Intermediate filaments,Primary cilium" No Yes "Cluster 45: Eosinophils - Unknown function" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 23 "Nuclear membrane, Intermediate filaments" "Primary cilium" "HPA003435: , HPA050204: " "unprognostic (1.48e-1)" "unprognostic (4.28e-2)" "unprognostic (3.47e-1)" "unprognostic (3.04e-2)" "unprognostic (1.80e-1)" "unprognostic (1.07e-1)" "unprognostic (2.10e-1)" "unprognostic (4.82e-3)" "unprognostic (3.44e-1)" "unprognostic (1.84e-2)" "unprognostic (2.46e-2)" "potential prognostic favorable (1.11e-4)" "potential prognostic favorable (3.48e-4)" "unprognostic (2.37e-2)" "unprognostic (8.78e-2)" "unprognostic (2.54e-1)" "unprognostic (1.01e-1)" "unprognostic (2.19e-3)" "unprognostic (5.79e-2)" "unprognostic (1.20e-2)" "unprognostic (4.96e-3)" "unprognostic (3.03e-2)" "unprognostic (6.57e-2)" "unprognostic (1.08e-1)" "unprognostic (1.02e-1)" "unprognostic (1.51e-1)" "unprognostic (9.74e-2)" "unprognostic (2.69e-1)" "unprognostic (5.11e-2)" "unprognostic (1.19e-1)" "unprognostic (6.28e-2)" SYNE3 "C14orf139, C14orf49, FLJ25605, LINC00341, NCRNA00341, Nesp3, Nesprin-3, NET53" ENSG00000176438 "Spectrin repeat containing nuclear envelope family member 3" Q6ZMZ3 14 95407266-95516650 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 12.3" "Cell type enhanced" "Detected in many" "Adipocytes: 290.9;Adrenal medulla cells: 106.4;Fibro-adipogenic progenitors: 176.9;Monocyte progenitors: 84.4;Plasma cells: 93.0;Rod photoreceptor cells: 118.8;Sertoli cells: 121.2;Tuft cells: 115.3" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 66.3;oligodendrocyte: 45.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Myeloma: 14.8" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Testis - Sertoli cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA055227, HPA077140" Approved Supported "Nuclear membrane" NA NA "Cluster 32: Basophils - Transcription" "Cluster 40: Non-specific - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 6: Leukemia - Signal transduction" "Cluster 89: Adipocytes - Lipid metabolism" 3 "Nuclear membrane" "HPA055227: , HPA077140: " "unprognostic (2.79e-1)" "unprognostic (2.20e-2)" "unprognostic (3.17e-1)" "unprognostic (1.62e-1)" "unprognostic (8.71e-2)" "unprognostic (1.81e-2)" "potential prognostic favorable (2.91e-4)" "unprognostic (3.41e-3)" "unprognostic (2.31e-2)" "unprognostic (5.20e-2)" "unprognostic (2.48e-2)" "unprognostic (1.27e-1)" "unprognostic (2.68e-1)" "unprognostic (4.93e-3)" "unprognostic (1.87e-2)" "unprognostic (1.69e-1)" "unprognostic (1.99e-1)" "unprognostic (1.22e-1)" "unprognostic (3.06e-2)" SYNE4 "C19orf46, DFNB76, FLJ36445, Nesp4, Nesprin-4" ENSG00000181392 "Spectrin repeat containing nuclear envelope family member 4" Q8N205 19 36003307-36008813 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast lactating cells: 48.9;Breast myoepithelial cells: 35.3;Cytotrophoblasts: 43.5;Epididymal efferent duct absorptive cells: 45.4;Migrating cytotrophoblasts: 40.1;Syncytiotrophoblasts: 43.6" "Group enriched" "Detected in many" 4 "cerebellar inhibitory: 12.3;choroid plexus epithelial cell: 7.7;lower rhombic lip: 18.1;mammillary body: 14.6;splatter: 10.2;thalamic excitatory: 7.5;upper rhombic lip: 19.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 22.6;prostate cancer: 30.1" "Breast - Breast glandular cells, Liver - Hepatocytes, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells" "Region enriched" "Detected in single" 15 "cerebellum: 6.8" "Not detected" "Not detected" HPA060253 Uncertain NA NA "Cluster 20: Pituitary gland - Hormone signaling" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 60: Prostate cancer - Unknown function" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 50 "HPA060253: " "unprognostic (4.37e-2)" "unprognostic (2.09e-1)" "unprognostic (1.68e-2)" "unprognostic (7.44e-2)" "unprognostic (1.23e-1)" "unprognostic (9.39e-3)" "unprognostic (4.51e-1)" "potential prognostic favorable (7.72e-4)" "unprognostic (2.66e-2)" "unprognostic (7.61e-3)" "unprognostic (2.16e-2)" "unprognostic (1.19e-1)" "unprognostic (1.77e-2)" "unprognostic (2.65e-1)" "unprognostic (7.76e-2)" "unprognostic (3.21e-3)" "unprognostic (1.30e-1)" "unprognostic (1.15e-2)" "unprognostic (9.08e-3)" "unprognostic (9.52e-2)" "unprognostic (1.73e-1)" "unprognostic (1.40e-1)" "unprognostic (5.82e-2)" "unprognostic (7.09e-2)" SYNGAP1 "KIAA1938, RASA5, SYNGAP" ENSG00000197283 "Synaptic Ras GTPase activating protein 1" Q96PV0 6 33419661-33453689 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "GTPase activation" "Autism, Autism spectrum disorder, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 56.7;Bergmann glia: 36.1;Brain excitatory neurons: 57.2;Brain inhibitory neurons: 48.2;Choroid plexus epithelial cells: 119.1;Ependymal cells: 90.7;Oligodendrocyte progenitor cells: 23.7;Other brain neurons: 32.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Liver - Vascular endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038373, HPA038374" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Nuclear bodies,Intermediate filaments,Primary cilium,Primary cilium tip,Basal body,Cytosol" NA NA "Cluster 65: Brain - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 35: Neurons - Synaptic function & neurogenesis" 48 "Nucleoplasm, Cytosol" "Nucleoli fibrillar center, Nuclear bodies, Intermediate filaments, Primary cilium, Primary cilium tip, Basal body" "HPA038373: , HPA038374: " "unprognostic (4.87e-2)" "unprognostic (1.12e-1)" "unprognostic (3.96e-1)" "unprognostic (3.33e-3)" "unprognostic (3.62e-3)" "unprognostic (1.07e-1)" "unprognostic (2.59e-1)" "unprognostic (2.57e-1)" "unprognostic (2.52e-2)" "unprognostic (5.41e-2)" "unprognostic (1.98e-2)" "unprognostic (3.20e-2)" "unprognostic (2.97e-2)" "unprognostic (1.54e-1)" "unprognostic (9.37e-3)" "unprognostic (1.59e-1)" "unprognostic (8.49e-2)" "unprognostic (3.85e-2)" "unprognostic (4.73e-3)" "unprognostic (4.04e-1)" "unprognostic (5.18e-2)" "unprognostic (1.25e-3)" "unprognostic (5.90e-2)" "unprognostic (4.88e-3)" "unprognostic (3.54e-1)" "unprognostic (8.23e-2)" "unprognostic (1.21e-2)" "unprognostic (1.25e-1)" "potential prognostic unfavorable (1.74e-4)" "unprognostic (2.15e-1)" SYNGR1 ENSG00000100321 "Synaptogyrin 1" O43759 22 39349925-39385575 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 224.7" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 388.2;Esophageal apical cells: 430.5;Esophageal suprabasal cells: 202.5;Melanocytes: 192.9;Retinal bipolar cells: 179.5" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 103.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 7 "dendritic cells: 44.8;monocytes: 39.0;T-cells: 30.9" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Cardiomyocytes, Liver - Hepatic stellate cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029673, CAB034277" Enhanced Supported Cytosol NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 27: Cerebellum - Synaptic function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 3 Cytosol "CAB034277: , HPA029673: " "unprognostic (1.06e-2)" "unprognostic (4.89e-3)" "unprognostic (4.45e-2)" "unprognostic (4.86e-2)" "unprognostic (2.65e-1)" "unprognostic (1.00e-1)" "unprognostic (1.04e-1)" "unprognostic (1.16e-2)" "unprognostic (3.77e-2)" "unprognostic (5.84e-2)" "unprognostic (9.01e-2)" "potential prognostic favorable (2.55e-5)" "potential prognostic favorable (4.80e-5)" "unprognostic (6.16e-2)" "unprognostic (3.32e-1)" "unprognostic (8.23e-3)" "unprognostic (1.65e-2)" "unprognostic (8.26e-2)" "potential prognostic favorable (3.90e-4)" "unprognostic (1.56e-2)" "unprognostic (2.61e-1)" "potential prognostic favorable (1.98e-4)" "unprognostic (4.12e-1)" "unprognostic (1.93e-2)" "unprognostic (1.10e-2)" "unprognostic (1.35e-1)" "unprognostic (3.01e-2)" "potential prognostic unfavorable (1.07e-4)" "unprognostic (6.79e-2)" "unprognostic (3.82e-3)" "unprognostic (1.14e-3)" SYNGR2 ENSG00000108639 "Synaptogyrin 2" O43760 17 78168581-78173527 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 246.2;Esophageal suprabasal cells: 250.7;Goblet cells: 261.1" "Group enriched" "Detected in many" 5 "central nervous system macrophage: 43.3;committed oligodendrocyte precursor: 27.4;endothelial cell: 57.5;fibroblast: 17.5;leukocyte: 33.9;oligodendrocyte: 58.6;pericyte: 43.8;vascular associated smooth muscle cell: 43.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014742 Approved Approved "Golgi apparatus" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 24: Non-specific - Transcription" "Cluster 30: White matter - Myelination" "Cluster 55: Lymphoma - Immune response" "Cluster 82: Dendritic cells - Antigen presentation" 20 "Golgi apparatus" "HPA014742: " "unprognostic (1.39e-1)" "unprognostic (2.38e-1)" "unprognostic (4.47e-2)" "unprognostic (6.05e-3)" "unprognostic (2.24e-1)" "unprognostic (1.48e-1)" "unprognostic (6.12e-2)" "unprognostic (4.42e-2)" "unprognostic (7.20e-2)" "unprognostic (8.07e-2)" "unprognostic (6.73e-2)" "unprognostic (8.53e-2)" "unprognostic (6.05e-2)" "unprognostic (1.12e-3)" "potential prognostic unfavorable (6.58e-6)" "potential prognostic unfavorable (3.38e-4)" "unprognostic (6.60e-2)" "unprognostic (1.57e-1)" "unprognostic (4.04e-1)" "unprognostic (2.20e-1)" "unprognostic (1.96e-2)" "unprognostic (8.72e-2)" "unprognostic (4.55e-3)" "unprognostic (4.00e-2)" "unprognostic (2.59e-1)" "unprognostic (5.21e-2)" "unprognostic (5.56e-2)" "unprognostic (2.58e-2)" "unprognostic (5.36e-3)" "unprognostic (1.77e-1)" "unprognostic (5.75e-2)" SYNGR3 ENSG00000127561 "Synaptogyrin 3" O43761 16 1989660-1994275 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "brain: 125.4" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 10.6;Brain excitatory neurons: 29.1;Brain inhibitory neurons: 40.7;Oocytes: 36.8;Other brain neurons: 63.9;Retinal amacrine cells: 9.0;Retinal ganglion cells: 11.6;Undifferentiated spermatogonia: 12.5" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 58.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Spleen - B-cells (Spleen), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034278, HPA042842, HPA049459" Enhanced Approved "Golgi apparatus,Vesicles" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 1: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 98: Neurons - Neurotransmission & signaling" 17 "Golgi apparatus" Vesicles "CAB034278: , HPA042842: , HPA049459: " "unprognostic (1.13e-1)" "unprognostic (1.88e-2)" "unprognostic (2.83e-1)" "unprognostic (3.38e-3)" "unprognostic (4.32e-2)" "unprognostic (1.40e-1)" "unprognostic (2.81e-2)" "unprognostic (3.72e-2)" "unprognostic (7.29e-3)" "unprognostic (1.69e-2)" "unprognostic (1.91e-3)" "potential prognostic favorable (2.66e-4)" "unprognostic (8.15e-2)" "unprognostic (8.69e-2)" "unprognostic (1.73e-1)" "unprognostic (1.23e-1)" "unprognostic (1.02e-1)" "unprognostic (4.78e-2)" "unprognostic (1.10e-1)" "unprognostic (8.61e-3)" "unprognostic (4.71e-2)" "unprognostic (3.02e-2)" "unprognostic (1.52e-1)" "unprognostic (2.40e-2)" "unprognostic (2.01e-1)" "unprognostic (2.24e-1)" "unprognostic (1.90e-2)" SYNGR4 ENSG00000105467 "Synaptogyrin 4" O95473 19 48364367-48376377 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 49.5" "Cell type enhanced" "Detected in some" "Early primary spermatocytes: 197.9;Early spermatids: 34.8;Late primary spermatocytes: 125.8;Late spermatids: 26.9;Pancreatic islet cells: 48.7" "Cell type enhanced" "Detected in some" "upper rhombic lip: 3.0" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 5.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 18.8" "Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA030075, HPA059286" Enhanced Approved "Golgi apparatus" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 35: Non-specific - DNA binding" "Cluster 40: Non-specific - Unknown function" "Cluster 3: Early primary spermatocytes - Early meiosis" 1 "Golgi apparatus" "HPA030075: , HPA059286: " "unprognostic (2.96e-1)" "unprognostic (2.76e-1)" "unprognostic (4.45e-3)" "unprognostic (1.82e-1)" "unprognostic (3.25e-2)" "unprognostic (2.92e-2)" "unprognostic (4.17e-3)" "unprognostic (1.33e-2)" "unprognostic (1.99e-2)" "unprognostic (7.47e-3)" "unprognostic (1.19e-2)" SYNJ1 "INPP5G, PARK20" ENSG00000159082 "Synaptojanin 1" O43426 21 32628759-32728040 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Endocytosis, Lipid metabolism" "Hydrolase, RNA-binding" "Disease variant, Epilepsy, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 38.6;retina: 44.8" "Cell type enhanced" "Detected in all" "Choroid plexus epithelial cells: 250.0;Neutrophil progenitors: 404.2;Neutrophils: 455.9;Rod photoreceptor cells: 178.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011916 Enhanced Approved Nucleoplasm,Centrosome,Cytosol NA NA 2900 "Cluster 35: Neutrophils - Protein binding" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 47: Leukemia - Hemostasis" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 20 "Nucleoplasm, Cytosol" Centrosome "HPA011916: " "unprognostic (7.86e-3)" "unprognostic (1.27e-2)" "unprognostic (1.98e-1)" "unprognostic (1.56e-1)" "unprognostic (1.87e-1)" "unprognostic (4.98e-2)" "unprognostic (6.91e-2)" "unprognostic (1.15e-1)" "potential prognostic favorable (6.41e-4)" "unprognostic (4.22e-2)" "potential prognostic favorable (4.81e-4)" "unprognostic (1.45e-3)" "unprognostic (5.78e-2)" "unprognostic (1.32e-1)" "unprognostic (9.81e-2)" "unprognostic (1.04e-2)" "unprognostic (2.73e-2)" "unprognostic (1.48e-1)" "unprognostic (2.24e-1)" "unprognostic (5.48e-2)" "unprognostic (4.00e-2)" "unprognostic (9.63e-3)" "unprognostic (7.54e-2)" "potential prognostic unfavorable (2.45e-4)" "unprognostic (3.00e-2)" "unprognostic (3.49e-2)" "unprognostic (6.19e-2)" "unprognostic (3.71e-2)" "unprognostic (5.60e-2)" "unprognostic (1.74e-1)" "unprognostic (2.50e-1)" SYNJ2 INPP5H ENSG00000078269 "Synaptojanin 2" O15056 6 157981863-158099176 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "brain: 115.1" "Cell type enhanced" "Detected in many" "Endometrial luminal cells: 439.0;Endometrial secretory cells: 360.4;Oligodendrocytes: 615.9" "Cell type enriched" "Detected in all" 4 "oligodendrocyte: 978.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031575 Approved Approved Microtubules,Cytosol NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 72: Neuronal - Signal transduction" "Cluster 51: Secretory epithelial cells - Mixed function" 19 Microtubules Cytosol "HPA031575: " "unprognostic (1.29e-1)" "potential prognostic unfavorable (5.33e-6)" "unprognostic (2.56e-1)" "unprognostic (1.80e-2)" "unprognostic (4.85e-2)" "unprognostic (6.99e-2)" "unprognostic (2.12e-2)" "unprognostic (1.26e-2)" "unprognostic (1.40e-1)" "unprognostic (1.56e-2)" "unprognostic (1.82e-1)" "unprognostic (1.33e-2)" "unprognostic (6.03e-2)" "unprognostic (2.81e-2)" "unprognostic (5.09e-3)" "unprognostic (5.04e-3)" "unprognostic (4.47e-3)" "unprognostic (5.33e-2)" "unprognostic (1.74e-3)" "potential prognostic unfavorable (9.00e-4)" "unprognostic (1.23e-1)" "unprognostic (2.06e-1)" "unprognostic (6.22e-2)" "unprognostic (3.73e-1)" "unprognostic (3.98e-2)" "unprognostic (9.75e-3)" "unprognostic (1.47e-2)" "unprognostic (8.60e-2)" "unprognostic (1.77e-1)" "unprognostic (2.51e-1)" "unprognostic (3.58e-2)" SYNJ2BP Arip2 ENSG00000213463 "Synaptojanin 2 binding protein" P57105 14 70366499-70417090 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 1.6;Brain inhibitory neurons: 1.3;Enterocytes: 1.4;Epididymal clear cells: 2.0;Gastric chief cells: 2.2;Goblet cells: 1.1;Late primary spermatocytes: 1.8;Microglia: 1.5;Mucous neck cells: 1.2;Other brain neurons: 1.5;Parietal cells: 3.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Spleen - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000866 Approved Supported Approved Mitochondria NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 76: Non-specific - Metabolism" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 98: Neurons - Neurotransmission & signaling" 55 Mitochondria "HPA000866: " "unprognostic (8.31e-2)" "unprognostic (2.02e-1)" "unprognostic (1.13e-1)" "unprognostic (7.89e-2)" "unprognostic (2.22e-1)" "unprognostic (1.05e-1)" "unprognostic (1.09e-1)" "unprognostic (1.97e-1)" "unprognostic (2.41e-1)" "potential prognostic unfavorable (9.51e-4)" "validated prognostic favorable (3.76e-9)" "validated prognostic favorable (3.04e-5)" "potential prognostic favorable (9.76e-4)" "unprognostic (4.05e-1)" "unprognostic (3.06e-1)" "unprognostic (2.45e-1)" "unprognostic (1.36e-1)" "unprognostic (2.43e-2)" "unprognostic (7.09e-2)" "unprognostic (1.21e-1)" "unprognostic (3.40e-3)" "unprognostic (1.51e-2)" "unprognostic (6.63e-2)" "unprognostic (1.82e-2)" "unprognostic (5.63e-2)" "unprognostic (1.57e-2)" "unprognostic (2.41e-2)" "unprognostic (3.95e-1)" "unprognostic (1.11e-1)" "unprognostic (3.12e-3)" "unprognostic (2.76e-2)" SYNJ2BP-COX16 ENSG00000258644 "SYNJ2BP-COX16 readthrough" 14 70326064-70417074 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "testis: 9.7" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 4.4;Hepatocytes: 1.7;Late primary spermatocytes: 2.6;Loop of henle epithelial cells: 3.1;Papillary tip epithelial cells: 1.6;Parietal cells: 1.8;Podocytes: 5.4;Proximal tubule cells: 2.3;Renal collecting duct intercalated cells: 4.0;Renal collecting duct principal cells: 4.8;Renal connecting tubule cells: 4.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA000866, HPA062659" Approved Supported Approved Mitochondria NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 21: Non-specific - Metabolism" "Cluster 61: BICR 18 - Protein kinases" "Cluster 105: Non-specific - Mixed function" Mitochondria "HPA000866: , HPA062659: " "unprognostic (2.04e-2)" "unprognostic (3.85e-2)" "unprognostic (2.63e-2)" "unprognostic (9.45e-3)" "unprognostic (2.27e-1)" "potential prognostic unfavorable (6.65e-4)" "unprognostic (4.81e-1)" "unprognostic (1.73e-2)" "unprognostic (9.30e-2)" "unprognostic (1.65e-1)" "unprognostic (1.65e-1)" "unprognostic (1.38e-3)" "unprognostic (2.31e-2)" "unprognostic (1.43e-1)" "unprognostic (5.52e-2)" "unprognostic (1.95e-2)" "unprognostic (5.67e-3)" "unprognostic (2.39e-1)" "unprognostic (2.06e-1)" "unprognostic (3.98e-2)" "unprognostic (6.52e-2)" "unprognostic (1.91e-1)" "unprognostic (2.92e-3)" "unprognostic (3.33e-1)" SYNM "DMN, KIAA0353, SYN" ENSG00000182253 Synemin O15061 15 99098217-99135593 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 563.8;skeletal muscle: 585.1;urinary bladder: 445.8" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 485.7;Breast secretory cells: 126.6;Cardiomyocytes: 129.4;Müller glia: 139.8;Myonuclei: 204.7;Pituicytes/FSCs: 240.3;Retinal pigment epithelial cells: 127.9;Salivary myoepithelial cells: 165.7;Smooth muscle cells: 1015.0;Thymic myoid cells: 213.5;Vascular smooth muscle cells: 229.8" "Cell type enhanced" "Detected in all" "pericyte: 115.9;vascular associated smooth muscle cell: 117.7" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 61.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "skin cancer: 75.0" "Adipose subcutaneous - Smooth muscle cells, Breast - Breast myoepithelial cells, Colon - Smooth muscle cells, Minor Salivary Gland - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017192, HPA040066, HPA044200, HPA077856" Enhanced Supported "Intermediate filaments" NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 7 "Intermediate filaments" "CAB017192: , HPA040066: , HPA044200: , HPA077856: " "unprognostic (1.08e-2)" "unprognostic (3.40e-2)" "unprognostic (1.45e-1)" "unprognostic (1.62e-1)" "unprognostic (9.77e-3)" "unprognostic (1.50e-1)" "unprognostic (2.39e-1)" "unprognostic (6.65e-2)" "unprognostic (1.10e-1)" "unprognostic (7.37e-2)" "validated prognostic favorable (2.70e-4)" "validated prognostic favorable (1.40e-5)" "unprognostic (1.20e-1)" "unprognostic (2.50e-2)" "unprognostic (7.74e-2)" "unprognostic (1.04e-1)" "unprognostic (7.31e-2)" "unprognostic (1.21e-2)" "unprognostic (5.45e-2)" "unprognostic (4.02e-2)" "unprognostic (2.42e-1)" "unprognostic (1.03e-2)" "unprognostic (1.25e-1)" "unprognostic (1.81e-2)" "unprognostic (7.60e-2)" "unprognostic (2.52e-2)" "unprognostic (1.29e-1)" "unprognostic (2.27e-2)" "unprognostic (1.02e-2)" "unprognostic (1.61e-3)" "unprognostic (7.65e-2)" SYNPO KIAA1029 ENSG00000171992 Synaptopodin Q8N3V7 5 150601080-150659207 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "blood vessel: 357.2;heart muscle: 344.8;skeletal muscle: 1214.5;tongue: 468.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 72.7;Cardiomyocytes: 70.9;Colonocytes: 64.1;Enterocytes: 78.7;Myonuclei: 196.5;Pancreatic duct cells: 81.2;Pancreatic islet cells: 92.1;Podocytes: 144.0;Vascular endothelial cells: 93.4;Vascular smooth muscle cells: 79.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.0" "Lineage enriched" "Detected in single" 10 "B-cells: 1.0" "Cancer enriched" "Detected in all" 5 "Kidney cancer: 181.1" "Adrenal gland - Adrenal cortex cells, Breast - Endothelial cells, Heart muscle - Cardiomyocytes, Minor Salivary Gland - Endothelial cells, Pituitary gland - Endothelial cells, Spleen - Fibroblasts_1, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033265, HPA034631, CAB037325, HPA071347" Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 51: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 12 "Plasma membrane, Cytosol" "Actin filaments" "CAB033265: , CAB037325: , HPA034631: , HPA071347: " "unprognostic (1.20e-1)" "unprognostic (7.59e-2)" "unprognostic (9.67e-2)" "potential prognostic unfavorable (4.50e-4)" "unprognostic (1.46e-1)" "unprognostic (4.50e-2)" "unprognostic (4.76e-2)" "potential prognostic unfavorable (3.59e-5)" "unprognostic (3.30e-2)" "unprognostic (2.82e-2)" "unprognostic (5.94e-2)" "unprognostic (3.69e-2)" "unprognostic (6.78e-3)" "unprognostic (1.78e-1)" "potential prognostic favorable (1.44e-5)" "unprognostic (1.17e-3)" "unprognostic (2.96e-1)" "unprognostic (1.49e-2)" "unprognostic (7.17e-3)" "unprognostic (3.95e-2)" "unprognostic (1.39e-2)" "unprognostic (5.16e-2)" "unprognostic (9.33e-2)" "unprognostic (6.40e-2)" "unprognostic (9.66e-3)" "unprognostic (1.24e-1)" "unprognostic (7.36e-3)" "unprognostic (2.84e-2)" "unprognostic (1.05e-1)" "unprognostic (2.26e-1)" "unprognostic (6.60e-2)" SYNPO2 "MYOPODIN, SYISL" ENSG00000172403 "Synaptopodin 2" Q9UMS6 4 118850688-119061247 "Predicted intracellular proteins" "Actin-binding, Muscle protein" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 952.4;tongue: 460.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 1047.2;Endometrial stromal cells: 356.6;Medullary thymic epithelial cells: 463.2;Myonuclei: 974.7;Pericytes: 552.8;Sertoli cells: 588.3;Smooth muscle cells: 2284.8;Thymic myoid cells: 1514.6;Vascular smooth muscle cells: 813.9" "Cell type enhanced" "Detected in all" "vascular associated smooth muscle cell: 736.4" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 47.9;Stomach Adenocarcinoma (TCGA): 68.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Neuroblastoma: 46.7;Rhabdoid: 17.0" "Adipose subcutaneous - Smooth muscle cells, Breast - Endothelial cells, Colon - Smooth muscle cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Smooth muscle cells, Minor Salivary Gland - Endothelial cells, Prostate - Smooth muscle cells, Spleen - Fibroblasts_1, Thyroid gland - Smooth muscle cells" "Region enriched" "Detected in all" 4 "thalamus: 27.1" "Low region specificity" "Detected in all" "HPA030665, CAB037231, HPA049707, HPA068563" Enhanced Enhanced "Vesicles,Actin filaments" NA NA 7300 "Cluster 25: Non-specific - Basic cellular processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 4 "Vesicles, Actin filaments" "CAB037231: , HPA030665: , HPA049707: , HPA068563: " "potential prognostic favorable (6.17e-4)" "unprognostic (2.59e-2)" "unprognostic (1.92e-2)" "unprognostic (1.92e-1)" "unprognostic (1.62e-1)" "unprognostic (4.38e-2)" "unprognostic (1.63e-1)" "unprognostic (1.19e-2)" "unprognostic (2.69e-1)" "unprognostic (1.76e-1)" "potential prognostic favorable (1.57e-4)" "unprognostic (1.68e-3)" "potential prognostic unfavorable (4.93e-4)" "unprognostic (1.06e-3)" "unprognostic (3.14e-2)" "unprognostic (1.53e-2)" "unprognostic (1.17e-1)" "unprognostic (6.74e-2)" "unprognostic (7.45e-2)" "unprognostic (2.35e-1)" "unprognostic (1.11e-2)" "unprognostic (9.32e-2)" "unprognostic (1.84e-2)" "unprognostic (7.43e-2)" "unprognostic (1.25e-1)" "unprognostic (3.66e-2)" "unprognostic (1.51e-1)" "unprognostic (1.49e-3)" "unprognostic (3.07e-1)" "unprognostic (1.43e-1)" "unprognostic (2.20e-1)" SYNPO2L FLJ12921 ENSG00000166317 "Synaptopodin 2 like" Q9H987 10 73644881-73663803 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 17 "heart muscle: 245.3;skeletal muscle: 261.4;tongue: 81.5" "Group enriched" "Detected in some" 5 "Cardiomyocytes: 194.9;Myonuclei: 90.5;Thymic myoid cells: 183.5" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Breast Invasive Carcinoma (TCGA): 4.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Sarcoma: 2.8" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Spleen - Smooth muscle cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA055192, HPA057142" Enhanced NA NA "Cluster 41: Striated muscle - Muscle contraction" "Cluster 6: Non-specific - Immune response" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" "HPA055192: , HPA057142: " "unprognostic (2.12e-1)" "unprognostic (4.35e-2)" "unprognostic (3.79e-1)" "unprognostic (4.43e-2)" SYNPR "MGC26651, SPO" ENSG00000163630 Synaptoporin Q8TBG9 3 63228315-63616924 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 262.1" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 433.6;Brain inhibitory neurons: 723.6;Other brain neurons: 125.8;Pituitary stem cells: 190.7;Retinal amacrine cells: 872.1;Retinal horizontal cells: 831.4" "Cell type enhanced" "Detected in all" "hippocampal dentate gyrus: 1174.4;midbrain-derived inhibitory: 2199.1" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 3.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bone cancer: 9.0;lymphoma: 2.4" "Region enhanced" "Detected in all" "olfactory bulb: 743.7" "Low region specificity" "Detected in all" "HPA051368, HPA061671" Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 33: Neurons - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 35: Neurons - Synaptic function & neurogenesis" 10 Vesicles "Nucleoplasm, Cytosol" "HPA051368: , HPA061671: " "unprognostic (1.39e-2)" "unprognostic (2.00e-1)" "unprognostic (6.12e-3)" "unprognostic (9.63e-2)" "unprognostic (5.89e-2)" "unprognostic (1.92e-1)" SYNRG "AP1GBP1, MGC104959, SYNG" ENSG00000275066 "Synergin gamma" Q9UMZ2 17 37514807-37609472 "Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 117.7;Distal convoluted tubule cells: 115.2;Microglia: 139.2;Proximal tubule cells: 119.8;Renal collecting duct intercalated cells: 140.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023554, HPA023555" Approved Approved Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 27: Breast cancer - Unknown function" "Cluster 102: Non-specific - Mixed function" 12 Cytosol "HPA023554: , HPA023555: " "potential prognostic favorable (8.95e-4)" "unprognostic (1.31e-1)" "unprognostic (3.43e-1)" "unprognostic (1.83e-2)" "unprognostic (1.84e-1)" "unprognostic (1.88e-3)" "unprognostic (1.21e-1)" "unprognostic (9.75e-2)" "unprognostic (9.35e-3)" "potential prognostic favorable (4.06e-5)" "unprognostic (2.03e-3)" "unprognostic (2.65e-1)" "unprognostic (5.39e-2)" "unprognostic (3.48e-1)" "unprognostic (5.04e-2)" "unprognostic (2.77e-1)" "unprognostic (1.29e-1)" "unprognostic (1.52e-2)" "unprognostic (3.30e-2)" "unprognostic (1.42e-1)" "unprognostic (1.55e-1)" "unprognostic (7.66e-3)" "unprognostic (1.78e-2)" "unprognostic (6.03e-2)" "unprognostic (3.83e-1)" "unprognostic (2.51e-1)" "unprognostic (1.08e-1)" "unprognostic (7.66e-2)" SYP MRX96 ENSG00000102003 Synaptophysin P08247 X 49187815-49200218 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 419.3;retina: 288.2" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 157.8;Brain inhibitory neurons: 142.2;Cone photoreceptor cells: 285.7;Corticotrophs: 97.7;Lactotrophs: 103.5;Neuroendocrine cells: 95.0;Other brain neurons: 149.1;Pancreatic islet cells: 108.6;Retinal amacrine cells: 182.7;Retinal bipolar cells: 391.6;Retinal ganglion cells: 119.7;Retinal horizontal cells: 118.2;Rod photoreceptor cells: 366.3;Somatotrophs: 117.9" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Glioblastoma Multiforme (TCGA): 45.8;Pancreatic Adenocarcinoma (TCGA): 16.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.7" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Neuroblastoma: 55.7" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000076, HPA002858, CAB055505, CAB078999, HPA079659" Enhanced Supported NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 67 "CAB000076: , CAB055505: , CAB078999: , HPA002858: , HPA079659: " "unprognostic (5.96e-2)" "unprognostic (1.58e-1)" "unprognostic (2.48e-1)" "unprognostic (1.86e-1)" "unprognostic (1.86e-1)" "unprognostic (1.04e-1)" "unprognostic (4.21e-2)" "unprognostic (1.58e-3)" "unprognostic (8.85e-3)" "unprognostic (1.11e-2)" "unprognostic (2.12e-1)" "unprognostic (1.63e-1)" "unprognostic (2.81e-1)" "unprognostic (6.64e-2)" "potential prognostic favorable (4.19e-4)" "unprognostic (4.01e-2)" "unprognostic (3.32e-1)" "unprognostic (5.18e-3)" "unprognostic (2.49e-1)" "unprognostic (7.03e-3)" "unprognostic (1.11e-3)" "unprognostic (2.32e-1)" "unprognostic (8.51e-2)" "potential prognostic unfavorable (7.27e-4)" "unprognostic (9.63e-3)" "unprognostic (1.77e-2)" "unprognostic (9.78e-2)" "unprognostic (1.72e-1)" "unprognostic (3.17e-2)" "unprognostic (1.58e-1)" SYPL1 SYPL ENSG00000008282 "Synaptophysin like 1" Q16563 7 106090505-106112589 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 592.0;Esophageal apical cells: 636.0;Esophageal suprabasal cells: 464.4;Late primary spermatocytes: 939.0" "Cell type enhanced" "Detected in all" "endothelial cell: 135.7;oligodendrocyte: 144.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014141 Approved NA NA "Cluster 32: Basophils - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 16 "HPA014141: " "unprognostic (6.72e-3)" "unprognostic (2.15e-1)" "unprognostic (7.97e-2)" "unprognostic (1.80e-1)" "unprognostic (1.42e-1)" "unprognostic (2.43e-2)" "unprognostic (3.97e-2)" "potential prognostic unfavorable (9.77e-6)" "unprognostic (6.94e-2)" "unprognostic (4.62e-2)" "potential prognostic favorable (3.10e-9)" "unprognostic (1.67e-2)" "unprognostic (1.10e-1)" "unprognostic (2.06e-2)" "unprognostic (1.86e-2)" "unprognostic (2.48e-2)" "unprognostic (1.84e-2)" "unprognostic (2.98e-3)" "unprognostic (3.12e-1)" "unprognostic (8.92e-2)" "unprognostic (1.21e-1)" "unprognostic (1.06e-3)" "unprognostic (9.57e-2)" "unprognostic (1.71e-1)" "unprognostic (3.35e-1)" "unprognostic (6.66e-2)" "unprognostic (3.29e-2)" "unprognostic (1.73e-1)" "unprognostic (2.17e-1)" "unprognostic (7.11e-2)" "unprognostic (2.67e-1)" SYPL2 Mg29 ENSG00000143028 "Synaptophysin like 2" Q5VXT5 1 109466546-109482134 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 14 "skeletal muscle: 340.5;tongue: 163.6" "Cell type enriched" "Detected in many" 6 "Myonuclei: 427.8" "Cell type enhanced" "Detected in some" "Bergmann glia: 21.5;choroid plexus epithelial cell: 11.3" "Group enriched" "Detected in many" 4 "Kidney Chromophobe (TCGA): 3.4;Kidney Renal Clear Cell Carcinoma (TCGA): 3.4;Kidney Renal Papillary Cell Carcinoma (TCGA): 10.2;Liver Hepatocellular Carcinoma (TCGA): 2.9;Thyroid Carcinoma (TCGA): 4.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 2.8;Sarcoma: 3.1" "Heart muscle - Cardiomyocytes, Pituitary gland - Undifferentiated cells (Pituitary gland), Prostate - Smooth muscle cells, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA076657 Approved "Plasma membrane,Cytosol" NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 23: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" Cytosol "Plasma membrane" "HPA076657: " "unprognostic (8.49e-2)" "unprognostic (2.21e-1)" "unprognostic (4.76e-3)" "unprognostic (1.83e-1)" "unprognostic (5.39e-2)" "potential prognostic favorable (8.07e-5)" "potential prognostic favorable (4.87e-7)" "unprognostic (7.67e-2)" "unprognostic (4.26e-2)" "unprognostic (1.45e-1)" "unprognostic (1.55e-1)" "unprognostic (3.38e-3)" SYS1 "C20orf169, dJ453C12.4" ENSG00000204070 "SYS1 golgi trafficking protein" Q8N2H4 20 45361937-45376798 "Essential proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 6.2;Bergmann glia: 10.3;Brain excitatory neurons: 9.6;Brain inhibitory neurons: 10.2;Cardiomyocytes: 7.7;Choroid plexus epithelial cells: 15.8;Ependymal cells: 16.1;Epicardial cells: 31.8;Microglia: 9.7;Oligodendrocyte progenitor cells: 6.6;Oligodendrocytes: 13.5;Other brain neurons: 11.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046716 Approved NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 21: Non-specific - Metabolism" "Cluster 62: Non-specific - Plasma proteins" "Cluster 22: Non-specific - Basic cellular functions" 14 "HPA046716: " "unprognostic (8.64e-3)" "unprognostic (1.51e-2)" "unprognostic (2.24e-1)" "unprognostic (1.35e-1)" "unprognostic (4.09e-2)" "unprognostic (7.49e-2)" "unprognostic (1.00e-1)" "unprognostic (3.13e-1)" "unprognostic (4.57e-2)" "unprognostic (3.23e-1)" "potential prognostic favorable (1.22e-5)" "unprognostic (4.75e-2)" "unprognostic (8.50e-2)" "potential prognostic unfavorable (3.70e-5)" "unprognostic (4.88e-3)" "unprognostic (4.66e-3)" "unprognostic (3.36e-2)" "unprognostic (3.80e-2)" "unprognostic (1.02e-1)" "unprognostic (1.76e-1)" "unprognostic (1.77e-2)" "unprognostic (4.52e-2)" "unprognostic (9.41e-2)" "unprognostic (3.45e-1)" "unprognostic (1.01e-1)" "unprognostic (1.17e-1)" "unprognostic (1.76e-1)" "unprognostic (6.54e-2)" "unprognostic (2.62e-1)" "unprognostic (1.75e-2)" "unprognostic (2.96e-1)" SYT1 "P65, SVP65, SYT" ENSG00000067715 "Synaptotagmin 1" P21579 12 78863993-79452008 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Differentiation "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "brain: 280.3;retina: 187.2" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 1372.2;Brain excitatory neurons: 3470.7;Brain inhibitory neurons: 3227.4;Cone photoreceptor cells: 3036.9;Epicardial cells: 1344.0;Other brain neurons: 2628.5;Prostatic glandular cells: 848.2;Retinal amacrine cells: 2721.0;Retinal bipolar cells: 2422.7;Retinal ganglion cells: 1344.2;Rod photoreceptor cells: 2549.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 14.0;Glioblastoma Multiforme (TCGA): 14.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.9;naive B-cell: 2.8" "Lineage enriched" "Detected in single" 4 "B-cells: 2.8" "Cancer enhanced" "Detected in many" "Neuroblastoma: 53.5" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008394, HPA064788" Enhanced Supported NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" 35 "HPA008394: , HPA064788: " "unprognostic (2.83e-1)" "unprognostic (2.76e-3)" "unprognostic (7.41e-2)" "unprognostic (3.01e-1)" "unprognostic (1.57e-2)" "unprognostic (1.22e-1)" "unprognostic (3.38e-2)" "unprognostic (1.43e-1)" "potential prognostic unfavorable (1.16e-4)" "unprognostic (1.14e-2)" "potential prognostic unfavorable (7.64e-4)" "unprognostic (5.97e-3)" "unprognostic (1.38e-1)" "unprognostic (1.63e-1)" "unprognostic (3.63e-1)" "unprognostic (1.75e-1)" "unprognostic (1.09e-1)" "unprognostic (1.58e-2)" "unprognostic (3.05e-3)" "unprognostic (4.26e-2)" "unprognostic (5.24e-2)" "unprognostic (2.17e-2)" "unprognostic (1.19e-1)" "unprognostic (1.06e-1)" "unprognostic (3.43e-3)" SYT10 ENSG00000110975 "Synaptotagmin 10" Q6XYQ8 12 33374238-33439819 "Predicted membrane proteins" Exocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "fallopian tube: 2.1" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 53.2;Brain inhibitory neurons: 37.0;Choroid plexus epithelial cells: 43.1;Ependymal cells: 120.5;Epididymal clear cells: 34.7;Fallopian tube ciliated cells: 65.6;Lactotrophs: 151.3;Other brain neurons: 53.8;Renal collecting duct intercalated cells: 91.9;Schwann cells: 49.1;Somatotrophs: 78.4;Thyrotrophs: 164.9" "Cell type enhanced" "Detected in many" "eccentric medium spiny neuron: 123.0;ependymal cell: 134.7;lower rhombic lip: 253.4" "Cancer enriched" "Detected in single" 4 "Kidney Chromophobe (TCGA): 3.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Enteric glia cells" "Region enhanced" "Detected in all" "olfactory bulb: 49.5" "Low region specificity" "Detected in all" HPA055426 Approved Nucleoplasm,Vesicles NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 24: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 1 "Nucleoplasm, Vesicles" "HPA055426: " "unprognostic (8.57e-2)" SYT11 "DKFZp781D015, KIAA0080, MGC10881, MGC17226" ENSG00000132718 "Synaptotagmin 11" Q9BT88 1 155859567-155885199 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 227.7" "Cell type enhanced" "Detected in many" "Astrocytes: 148.6;Bergmann glia: 132.3;Brain excitatory neurons: 112.3;Brain inhibitory neurons: 134.2;Corticotrophs: 103.2;Ependymal cells: 85.8;Lactotrophs: 80.3;Müller glia: 193.1;Oligodendrocyte progenitor cells: 196.0;Oligodendrocytes: 214.6;Other brain neurons: 122.8;Pituicytes/FSCs: 175.5;Retinal horizontal cells: 86.1;Schwann cells: 82.3" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 14 "Glioblastoma Multiforme (TCGA): 187.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Neuroblastoma: 87.9" "Adipose subcutaneous - Smooth muscle cells, Breast - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064091 Enhanced NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 73: Brain - Neuronal signaling" "Cluster 27: Non-specific - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 11 "HPA064091: " "unprognostic (2.63e-3)" "unprognostic (2.92e-1)" "unprognostic (2.38e-1)" "unprognostic (1.24e-1)" "unprognostic (1.87e-2)" "unprognostic (4.01e-2)" "unprognostic (3.14e-1)" "unprognostic (1.52e-1)" "unprognostic (1.05e-2)" "unprognostic (2.11e-1)" "potential prognostic favorable (1.45e-4)" "unprognostic (1.00e-1)" "unprognostic (9.37e-2)" "unprognostic (9.40e-2)" "unprognostic (9.63e-2)" "potential prognostic favorable (7.09e-4)" "unprognostic (6.19e-2)" "unprognostic (3.68e-1)" "unprognostic (1.33e-2)" "unprognostic (1.49e-2)" "unprognostic (2.55e-2)" "unprognostic (3.33e-2)" "unprognostic (2.49e-1)" "unprognostic (2.32e-1)" "unprognostic (2.50e-1)" "unprognostic (1.07e-3)" "unprognostic (2.70e-1)" "unprognostic (1.53e-1)" "unprognostic (1.61e-1)" "unprognostic (6.78e-2)" "unprognostic (3.44e-1)" SYT12 SRG1 ENSG00000173227 "Synaptotagmin 12" Q8IV01 11 67006778-67050863 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 49.4;liver: 21.4;parathyroid gland: 60.1" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 49.3;Brain inhibitory neurons: 34.5;Breast myoepithelial cells: 18.1;Breast secretory cells: 19.4;Ependymal cells: 15.7;Epididymal principal cells: 51.5;Other brain neurons: 19.7;Papillary tip epithelial cells: 13.9;Pituicytes/FSCs: 17.1;Pituitary stem cells: 53.1;Retinal amacrine cells: 15.7" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 33.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 35.7;cervical cancer: 26.5" "Adrenal gland - Adrenal cortex cells, Pancreas - Ductal cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011006, HPA074255" Enhanced NA NA "Cluster 69: Parathyroid gland - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 3 "HPA011006: , HPA074255: " "unprognostic (6.99e-3)" "unprognostic (1.54e-1)" "unprognostic (8.70e-2)" "unprognostic (6.54e-2)" "unprognostic (7.98e-2)" "unprognostic (1.28e-1)" "unprognostic (3.43e-2)" "unprognostic (5.16e-2)" "unprognostic (5.83e-2)" "unprognostic (2.84e-3)" "unprognostic (1.75e-1)" "unprognostic (2.43e-2)" "unprognostic (1.10e-1)" "potential prognostic unfavorable (6.69e-4)" "unprognostic (1.42e-2)" "unprognostic (8.79e-2)" "unprognostic (4.24e-3)" "unprognostic (1.04e-1)" "potential prognostic unfavorable (9.09e-4)" "unprognostic (1.09e-2)" "unprognostic (4.84e-1)" "unprognostic (3.01e-2)" "unprognostic (1.46e-1)" "unprognostic (2.51e-2)" "unprognostic (8.51e-3)" SYT13 KIAA1427 ENSG00000019505 "Synaptotagmin 13" Q7L8C5 11 45240302-45286341 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 43.7;gallbladder: 19.5" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 42.3;Brain inhibitory neurons: 38.4;Enteric stem cells: 38.8;Enteric transient amplifying cells: 36.5;Gastric progenitor cells: 32.0;Goblet cells: 37.6;Lactotrophs: 39.0;Neuroendocrine cells: 258.0;Other brain neurons: 48.5;Pancreatic islet cells: 52.8;Parietal cells: 81.3;Somatotrophs: 70.2;Thyrotrophs: 37.5" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 74.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Kidney cancer: 70.7" "Adrenal gland - Adrenal medulla cells, Heart muscle - Cardiomyocytes, Liver - Cholangiocytes, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Alpha cells, Pancreas - Beta cells, Pituitary gland - Somatotropes, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Stomach - Parietal cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046224, HPA056602" Uncertain Supported Vesicles NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" Vesicles "HPA046224: , HPA056602: " "unprognostic (2.40e-1)" "unprognostic (2.09e-2)" "unprognostic (1.41e-2)" "unprognostic (2.29e-3)" "unprognostic (8.14e-2)" "unprognostic (3.65e-2)" "unprognostic (1.46e-2)" "unprognostic (1.04e-1)" "unprognostic (5.84e-2)" "unprognostic (5.26e-2)" "unprognostic (3.82e-1)" "unprognostic (4.02e-2)" "unprognostic (7.34e-2)" "unprognostic (1.19e-1)" "unprognostic (1.11e-3)" "unprognostic (1.70e-1)" "unprognostic (1.51e-1)" "unprognostic (3.07e-1)" "unprognostic (1.40e-1)" "unprognostic (1.23e-1)" "unprognostic (2.61e-1)" "unprognostic (1.22e-1)" "unprognostic (3.11e-1)" "unprognostic (4.58e-2)" "unprognostic (9.80e-2)" "unprognostic (2.83e-2)" "unprognostic (2.76e-1)" "unprognostic (5.08e-2)" "unprognostic (1.15e-1)" SYT14 "FLJ34198, sytXIV" ENSG00000143469 "Synaptotagmin 14" Q8NB59 1 209900923-210171389 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "retina: 3.6;testis: 3.1;thyroid gland: 5.8" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 202.1;Brain excitatory neurons: 266.0;Brain inhibitory neurons: 317.6;Cone photoreceptor cells: 167.7;Corticotrophs: 267.2;Gonadotrophs: 418.0;Lactotrophs: 316.0;Oligodendrocyte progenitor cells: 234.2;Other brain neurons: 253.4;Pancreatic islet cells: 179.3;Pituicytes/FSCs: 160.6;Retinal amacrine cells: 209.8;Retinal bipolar cells: 171.4;Retinal ganglion cells: 239.5;Retinal horizontal cells: 272.5;Rod photoreceptor cells: 172.7;Somatotrophs: 402.5;Thyrotrophs: 425.7" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in single" "Thyroid Carcinoma (TCGA): 1.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 5.6" "Pancreas - Alpha cells, Pancreas - Beta cells, Prostate - Prostate glandular cells, Stomach - Gastric enteroendocrine cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036963 Supported Vesicles NA NA "Cluster 42: Retina - Visual perception" "Cluster 2: Neurons - Nucleosome" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" Vesicles "HPA036963: " "unprognostic (5.89e-2)" "unprognostic (3.42e-2)" "unprognostic (1.96e-1)" SYT15 CHR10SYT ENSG00000204176 "Synaptotagmin 15" "Q9BQS2, X6R8R1" 10 46578217-46594173 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 9.8;Alveolar cells type 2: 3.4;Esophageal suprabasal cells: 1.5;Kupffer cells: 2.0;Lymphatic endothelial cells: 2.9;Transitional alveolar cells: 2.0;Vascular endothelial cells: 9.1" "Cell type enriched" "Detected in some" 4 "endothelial cell: 17.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "HPA036971, HPA036972, HPA064559" Uncertain Approved "Golgi apparatus" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 13: Lung - Secretion" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "Golgi apparatus" "HPA036971: , HPA036972: , HPA064559: " "unprognostic (1.22e-2)" "unprognostic (1.63e-1)" "unprognostic (9.38e-2)" "unprognostic (6.68e-3)" "unprognostic (1.71e-1)" "unprognostic (2.38e-1)" "unprognostic (1.32e-1)" "unprognostic (4.69e-1)" "unprognostic (2.51e-1)" "unprognostic (4.40e-3)" "unprognostic (3.58e-2)" "unprognostic (1.21e-1)" "unprognostic (1.61e-1)" "unprognostic (1.36e-3)" "unprognostic (1.15e-1)" "unprognostic (5.97e-2)" "unprognostic (1.58e-1)" "unprognostic (2.11e-1)" "unprognostic (1.60e-1)" "unprognostic (8.69e-2)" "unprognostic (3.04e-2)" "unprognostic (7.52e-2)" "unprognostic (1.04e-1)" "unprognostic (3.53e-1)" "unprognostic (4.31e-2)" "unprognostic (9.29e-2)" "unprognostic (1.08e-1)" "unprognostic (1.52e-1)" "unprognostic (5.98e-2)" SYT15B ENSG00000277758 "Synaptotagmin 15B" X6R8R1 10 47744717-47763592 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Tissue enhanced" "Detected in many" "lung: 10.3" "Cell type enhanced" "Detected in single" "Thymic myoid cells: 1.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "HPA036971, HPA036972, HPA064559" Approved Approved "Golgi apparatus" NA NA "Cluster 13: Lung - Secretion" "Cluster 51: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 105: Non-specific - Mixed function" "Golgi apparatus" "HPA036971: , HPA036972: , HPA064559: " "unprognostic (1.64e-1)" "unprognostic (2.24e-1)" "unprognostic (6.74e-2)" "potential prognostic favorable (3.47e-4)" "unprognostic (3.91e-2)" "unprognostic (4.68e-2)" "unprognostic (1.43e-1)" "unprognostic (1.49e-2)" SYT16 "CHR14SYT, Strep14, SYT14L, yt14r" ENSG00000139973 "Synaptotagmin 16" Q17RD7 14 61811974-62112550 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.3;testis: 2.8" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 224.8;Brain inhibitory neurons: 293.0;Corticotrophs: 69.4;Early spermatids: 237.9;Ependymal cells: 113.8;Foveolar cells: 89.3;Oligodendrocyte progenitor cells: 203.8;Other brain neurons: 181.1;Pancreatic islet cells: 79.1;Pituitary stem cells: 78.8;Retinal amacrine cells: 75.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Pancreas - Beta cells, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004199, HPA076871" Enhanced Approved Cytosol NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Neurons - Synaptic function & neurogenesis" 26 Cytosol "HPA004199: , HPA076871: " "unprognostic (1.63e-1)" "unprognostic (1.77e-2)" "unprognostic (1.12e-1)" SYT17 Syt-17 ENSG00000103528 "Synaptotagmin 17" Q9BSW7 16 19167971-19268332 "Predicted intracellular proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.1;parathyroid gland: 23.8" "Cell type enhanced" "Detected in many" "Astrocytes: 179.5;Corticotrophs: 116.5;Ependymal cells: 223.6;Lactotrophs: 129.4;Microglia: 137.0;Oligodendrocyte progenitor cells: 157.7;Pituitary stem cells: 166.9;Renal collecting duct intercalated cells: 217.9;Respiratory ionocytes: 137.2;Thyrotrophs: 129.6" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 57.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "intermediate monocyte: 6.2;memory B-cell: 7.8;naive B-cell: 19.0;non-classical monocyte: 20.2" "Group enriched" "Detected in many" 9 "B-cells: 19.0;monocytes: 20.2" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042059 Approved Nucleoplasm,Cytosol NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 51: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 37 "Nucleoplasm, Cytosol" "HPA042059: " "unprognostic (4.18e-2)" "unprognostic (1.15e-1)" "unprognostic (2.26e-1)" "unprognostic (1.11e-1)" "unprognostic (5.18e-2)" "unprognostic (5.41e-2)" "unprognostic (2.43e-1)" "unprognostic (8.91e-3)" "unprognostic (4.43e-2)" "unprognostic (1.11e-3)" "unprognostic (1.39e-2)" "unprognostic (1.62e-2)" "unprognostic (2.20e-1)" "unprognostic (5.89e-2)" "potential prognostic favorable (2.80e-4)" "unprognostic (1.96e-1)" "unprognostic (5.21e-2)" "unprognostic (1.49e-1)" "unprognostic (1.35e-1)" "unprognostic (5.52e-2)" "unprognostic (2.11e-1)" "unprognostic (3.80e-1)" "potential prognostic unfavorable (6.91e-6)" "unprognostic (6.45e-2)" "unprognostic (1.54e-1)" "unprognostic (8.66e-3)" "unprognostic (2.20e-1)" "unprognostic (5.25e-2)" "unprognostic (2.44e-1)" "unprognostic (1.23e-3)" "unprognostic (1.87e-1)" SYT2 ENSG00000143858 "Synaptotagmin 2" Q8N9I0 1 202590596-202710454 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" Differentiation "Congenital myasthenic syndrome, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "brain: 39.3" "Cell type enhanced" "Detected in many" "Adipocytes: 73.7;Brain excitatory neurons: 46.5;Brain inhibitory neurons: 43.4;Cardiomyocytes: 192.8;Epicardial cells: 52.3;Granulosa cells: 40.5;Myonuclei: 67.8;Oocytes: 55.3;Retinal ganglion cells: 100.4;Salivary myoepithelial cells: 60.4" "Cell type enhanced" "Detected in all" "cerebellar inhibitory: 284.7;lower rhombic lip: 132.9" "Cancer enriched" "Detected in some" 7 "Testicular Germ Cell Tumor (TCGA): 9.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "thyroid cancer: 8.4" "Adrenal gland - Adrenal medulla cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA063655 Enhanced Supported NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 29 "HPA063655: " "unprognostic (2.13e-1)" "unprognostic (8.77e-3)" "unprognostic (7.94e-3)" "unprognostic (1.93e-2)" "unprognostic (2.47e-2)" "unprognostic (1.59e-1)" "unprognostic (1.71e-1)" SYT3 ENSG00000213023 "Synaptotagmin 3" Q9BQG1 19 50621307-50639881 "Predicted membrane proteins" Differentiation "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 24.5" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 12.9;Brain inhibitory neurons: 13.2;Cone photoreceptor cells: 8.3;Oligodendrocyte progenitor cells: 6.1;Other brain neurons: 14.1;Retinal amacrine cells: 11.8;Retinal bipolar cells: 6.0;Retinal ganglion cells: 7.7;Retinal pigment epithelial cells: 4.3;Undifferentiated spermatogonia: 4.3" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 4.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 6.4" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Lung - Alveolar cells type 2, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 98: Neurons - Neurotransmission & signaling" 10 "unprognostic (8.10e-3)" "unprognostic (5.85e-2)" "unprognostic (8.72e-2)" "unprognostic (8.23e-2)" "unprognostic (7.96e-2)" "unprognostic (2.59e-2)" "unprognostic (2.78e-1)" "unprognostic (3.33e-1)" "unprognostic (1.90e-1)" SYT4 "HsT1192, KIAA1342" ENSG00000132872 "Synaptotagmin 4" Q9H2B2 18 43267892-43277535 "Predicted intracellular proteins" Differentiation "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 140.6" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 63.8;Brain excitatory neurons: 121.9;Brain inhibitory neurons: 55.0;Corticotrophs: 117.1;Epicardial cells: 36.4;Gonadotrophs: 53.8;Lactotrophs: 81.2;Mesothelial cells: 30.1;Other brain neurons: 98.9;Pancreatic islet cells: 132.7;Retinal bipolar cells: 40.2;Somatotrophs: 108.5" "Cell type enhanced" "Detected in all" "upper rhombic lip: 236.5" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 3.7;Pancreatic Adenocarcinoma (TCGA): 6.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 53.9;prostate cancer: 46.4" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Stomach - Gastric enteroendocrine cells, Thyroid gland - Parafollicular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010574 Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 4 "Vesicles, Plasma membrane" "HPA010574: " "unprognostic (4.99e-1)" "unprognostic (1.51e-1)" "unprognostic (3.16e-2)" "unprognostic (3.34e-1)" "unprognostic (9.09e-2)" "unprognostic (1.39e-1)" "unprognostic (5.50e-3)" "unprognostic (1.26e-2)" "unprognostic (8.94e-3)" SYT5 ENSG00000129990 "Synaptotagmin 5" O00445 19 55171196-55180289 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 106.0;pituitary gland: 55.4" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 31.9;Brain excitatory neurons: 33.2;Brain inhibitory neurons: 33.7;Gonadotrophs: 38.9;Lactotrophs: 49.4;Late spermatids: 76.9;Neuroendocrine cells: 36.0;Other brain neurons: 47.4;Pancreatic islet cells: 91.0;Somatotrophs: 24.5;Thyrotrophs: 23.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 28.7;Rhabdoid: 34.2" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Pituitary gland - Lactotropes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078390 Enhanced NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 1 "HPA078390: " "unprognostic (1.04e-1)" "unprognostic (8.16e-2)" "unprognostic (3.73e-1)" "unprognostic (2.07e-1)" "unprognostic (9.99e-3)" "unprognostic (1.84e-2)" "unprognostic (2.92e-1)" "unprognostic (1.42e-1)" "unprognostic (1.39e-1)" "unprognostic (3.93e-2)" "unprognostic (1.18e-1)" "unprognostic (2.34e-1)" "unprognostic (1.48e-1)" "unprognostic (2.83e-1)" "unprognostic (1.37e-1)" "unprognostic (5.49e-3)" "unprognostic (7.06e-2)" "unprognostic (2.70e-1)" "unprognostic (1.34e-2)" "unprognostic (4.83e-2)" "unprognostic (1.68e-1)" "unprognostic (3.19e-2)" SYT6 ENSG00000134207 "Synaptotagmin 6" Q5T7P8 1 114089291-114153880 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 7.4;pancreas: 2.9" "Cell type enhanced" "Detected in some" "Brain inhibitory neurons: 18.4;Early spermatids: 20.9;Hepatic stellate cells: 12.9;Late spermatids: 26.4;Microglia: 127.0;Other brain neurons: 29.9;Pancreatic duct cells: 29.9;Proximal tubule cells: 20.3;Retinal amacrine cells: 80.5" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 151.0;midbrain-derived inhibitory: 59.1" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 4.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 5.5" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Testis - Late spermatids" "Group enriched" "Detected in all" 7 "basal ganglia: 31.3;olfactory bulb: 71.3" "Low region specificity" "Detected in many" HPA058362 Approved Vesicles NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" Vesicles "HPA058362: " "unprognostic (9.56e-2)" "unprognostic (1.00e-1)" "potential prognostic favorable (3.99e-7)" "unprognostic (1.21e-1)" "unprognostic (1.84e-1)" SYT7 "IPCA-7, MGC150517, PCANAP7, SYT-VII" ENSG00000011347 "Synaptotagmin 7" O43581 11 61513714-61581148 "Predicted intracellular proteins, Predicted membrane proteins" Exocytosis Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 60.4;liver: 79.3;prostate: 47.8;salivary gland: 53.7" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 73.7;Conjunctival goblet cells: 112.6;Cytotrophoblasts: 79.2;Gonadotrophs: 165.1;Hepatocytes: 84.7;Lactotrophs: 105.7;Neuroendocrine cells: 73.2;Pancreatic islet cells: 141.1;Prostatic glandular cells: 200.2;Retinal amacrine cells: 98.1;Salivary duct cells: 121.6;Somatotrophs: 167.9;Syncytiotrophoblasts: 103.9" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 97.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal medulla cells, Heart muscle - Cardiomyocytes, Pancreas - Alpha cells, Pancreas - Beta cells, Pituitary gland - Somatotropes, Prostate - Prostate glandular cells, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012869 Enhanced NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 2 "HPA012869: " "unprognostic (3.13e-1)" "unprognostic (5.77e-2)" "unprognostic (1.77e-3)" "unprognostic (5.47e-3)" "unprognostic (1.54e-1)" "unprognostic (1.10e-1)" "unprognostic (7.37e-2)" "unprognostic (2.71e-1)" "unprognostic (1.52e-3)" "unprognostic (2.43e-1)" "potential prognostic unfavorable (5.24e-7)" "unprognostic (6.76e-2)" "unprognostic (1.14e-1)" "unprognostic (1.63e-1)" "unprognostic (2.13e-1)" "potential prognostic unfavorable (2.25e-4)" "unprognostic (1.07e-2)" "unprognostic (2.27e-3)" "unprognostic (1.38e-1)" "unprognostic (1.60e-2)" "unprognostic (1.45e-3)" "unprognostic (3.13e-2)" "unprognostic (6.84e-2)" "unprognostic (3.24e-2)" "unprognostic (9.29e-3)" "unprognostic (1.73e-1)" "unprognostic (3.16e-1)" "unprognostic (4.95e-3)" "unprognostic (8.21e-3)" SYT8 DKFZp434K0322 ENSG00000149043 "Synaptotagmin 8" Q8NBV8 11 1828307-1837521 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 28.0;skin 1: 64.9;urinary bladder: 35.9" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 80.8;Breast myoepithelial cells: 201.5;Cholangiocytes: 47.8;Conjunctival goblet cells: 28.2;Extravillous trophoblasts: 41.5;Ocular epithelial cells: 131.2;Papillary tip epithelial cells: 71.5;Prostatic hillock cells: 55.8;Respiratory ciliated cells: 28.7;Urothelial cells: 71.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 23.7;Pancreatic Adenocarcinoma (TCGA): 33.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder cancer: 15.3;pancreatic cancer: 8.2" "Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary gland basal cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047239, HPA052700" Uncertain Approved "Nucleoli fibrillar center,Endoplasmic reticulum" NA NA "Cluster 58: Skin - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 1 "Nucleoli fibrillar center, Endoplasmic reticulum" "HPA047239: , HPA052700: " "unprognostic (1.43e-2)" "potential prognostic favorable (1.77e-4)" "unprognostic (2.76e-1)" "unprognostic (1.49e-1)" "unprognostic (1.57e-1)" "unprognostic (3.64e-2)" "unprognostic (8.16e-3)" "unprognostic (4.04e-3)" "unprognostic (2.51e-3)" "unprognostic (3.46e-1)" "unprognostic (1.41e-2)" "unprognostic (4.34e-2)" "unprognostic (3.51e-1)" "unprognostic (3.33e-2)" "unprognostic (1.45e-2)" "unprognostic (3.12e-2)" "unprognostic (1.28e-2)" SYT9 ENSG00000170743 "Synaptotagmin 9" Q86SS6 11 7238778-7469043 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.4;retina: 7.0" "Cell type enhanced" "Detected in many" "Astrocytes: 95.9;Brain excitatory neurons: 87.7;Cardiomyocytes: 177.6;Corticotrophs: 80.4;Gonadotrophs: 96.1;Late spermatids: 63.7;Oligodendrocyte progenitor cells: 92.3;Oligodendrocytes: 190.0;Podocytes: 110.7;Retinal bipolar cells: 151.5" "Cell type enhanced" "Detected in all" "midbrain-derived inhibitory: 283.2;oligodendrocyte: 249.4;upper rhombic lip: 251.1" "Cancer enhanced" "Detected in some" "Breast Invasive Carcinoma (TCGA): 3.1;Kidney Renal Clear Cell Carcinoma (TCGA): 2.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 8 "Neuroblastoma: 7.6" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells, Kidney - Proximal tubular cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 6 "unprognostic (8.92e-2)" "unprognostic (7.55e-2)" "unprognostic (5.87e-2)" "validated prognostic favorable (1.74e-6)" "validated prognostic favorable (8.45e-4)" SYTL1 "exophilin-7, FLJ14996, JFC1, SLP1" ENSG00000142765 "Synaptotagmin like 1" Q8IYJ3 1 27342020-27353937 "Plasma proteins, Predicted intracellular proteins" Exocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 98.8;pancreas: 101.4" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 375.2;Esophageal basal cells: 222.8;Esophageal suprabasal cells: 327.1;Fallopian tube ciliated cells: 124.9;Prostatic hillock cells: 144.0;Respiratory basal cells: 127.1;Suprabasal keratinocytes: 134.8" "Cell type enriched" "Detected in many" 4 "leukocyte: 76.8" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 88.7" "Group enriched" "Detected in all" 5 "amygdala: 8.4;cerebellum: 18.3;choroid plexus: 12.5" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 63.9" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Colon - T-cells, Heart muscle - T-cells, Liver - T-cells, Prostate - Prostate glandular cells, Thyroid gland - T-cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA037825 Enhanced NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 54: Non-specific - Ribosome" "Cluster 35: Non-specific - DNA binding" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 85: Squamous epithelial cells - Keratinization" 8 "HPA037825: " "unprognostic (2.83e-2)" "unprognostic (8.23e-2)" "unprognostic (1.73e-1)" "unprognostic (2.41e-1)" "unprognostic (2.39e-2)" "unprognostic (7.25e-2)" "unprognostic (3.77e-1)" "unprognostic (3.36e-2)" "unprognostic (4.14e-2)" "unprognostic (2.33e-1)" "unprognostic (1.38e-1)" "unprognostic (1.37e-2)" "unprognostic (1.68e-2)" "unprognostic (1.76e-1)" "unprognostic (1.90e-1)" "unprognostic (4.15e-1)" "unprognostic (8.72e-2)" "unprognostic (9.49e-2)" "unprognostic (6.69e-2)" "unprognostic (2.83e-1)" "unprognostic (1.80e-1)" "unprognostic (3.46e-1)" "unprognostic (3.28e-1)" "unprognostic (1.74e-1)" "unprognostic (2.30e-1)" "unprognostic (5.16e-1)" "unprognostic (1.32e-2)" "unprognostic (3.88e-2)" SYTL2 "CHR11SYT, exophilin-4, FLJ20163, FLJ21219, KIAA1597, MGC102768, PPP1R151, SGA72M, SLP2" ENSG00000137501 "Synaptotagmin like 2" Q9HCH5 11 85694224-85811159 "Plasma proteins, Predicted intracellular proteins, Transporters" Exocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 68.5;stomach 1: 118.9" "Cell type enhanced" "Detected in many" "Foveolar cells: 1989.1;Goblet cells: 942.2;Papillary tip epithelial cells: 427.9;Prostatic hillock cells: 353.6;Renal connecting tubule cells: 351.4;Salivary duct cells: 367.9;Urothelial cells: 556.9" "Cell type enhanced" "Detected in all" "vascular associated smooth muscle cell: 362.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 13.9;MAIT T-cell: 23.8" "Lineage enriched" "Detected in many" 6 "T-cells: 23.8" "Cancer enhanced" "Detected in many" "Kidney cancer: 85.8" "Adrenal gland - Adrenal cortex cells, Liver - Hepatic stellate cells, Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Fibroblasts, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039651 Approved Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 17: Intestine - Digestion" "Cluster 53: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 68: Foveolar cells - Mucosal defense" 3 "Nucleoplasm, Golgi apparatus" "Plasma membrane" "HPA039651: " "unprognostic (2.45e-2)" "potential prognostic unfavorable (2.77e-4)" "unprognostic (8.75e-2)" "unprognostic (1.99e-1)" "unprognostic (8.78e-2)" "unprognostic (9.91e-2)" "unprognostic (2.15e-2)" "unprognostic (1.47e-1)" "unprognostic (1.75e-3)" "unprognostic (2.11e-1)" "unprognostic (3.26e-1)" "unprognostic (9.60e-2)" "unprognostic (2.07e-2)" "unprognostic (2.44e-1)" "unprognostic (1.06e-1)" "unprognostic (2.41e-1)" "unprognostic (5.30e-3)" "unprognostic (6.59e-2)" "unprognostic (1.02e-2)" "unprognostic (3.88e-3)" "unprognostic (6.22e-3)" "unprognostic (3.68e-2)" "unprognostic (7.50e-2)" "unprognostic (1.78e-2)" "unprognostic (1.82e-2)" "unprognostic (3.34e-1)" "unprognostic (4.77e-1)" "unprognostic (3.88e-1)" "unprognostic (1.71e-1)" "unprognostic (2.20e-1)" "unprognostic (6.72e-2)" SYTL3 "exophilin-6, SLP3" ENSG00000164674 "Synaptotagmin like 3" Q4VX76 6 158650014-158764876 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 47.0" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 491.9;Endometrial glandular cells: 484.6;Epicardial cells: 923.3;Innate lymphoid cells: 1390.6;Mast cells: 1831.3;Neutrophils: 1072.4;NK-cells: 1924.6;T-cells: 1637.4;Thymocytes: 979.1" "Group enriched" "Detected in all" 5 "central nervous system macrophage: 175.7;choroid plexus epithelial cell: 345.3;leukocyte: 503.2" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 5 "choroid plexus: 49.9" "Immune cell enriched" "Detected in many" 5 "basophil: 232.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 232.8" "Cancer enhanced" "Detected in many" "Kidney cancer: 23.1;lymphoma: 22.9" "Adipose visceral - T-cells, Heart muscle - Cardiomyocytes, Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA030584, HPA030585, HPA030586" Approved Approved "Nucleoli fibrillar center,Vesicles" NA Yes "Cluster 41: Basophils - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 5 "Nucleoli fibrillar center, Vesicles" "HPA030584: , HPA030585: , HPA030586: " "unprognostic (1.13e-1)" "unprognostic (1.76e-3)" "unprognostic (3.15e-1)" "unprognostic (1.02e-3)" "unprognostic (6.82e-2)" "unprognostic (1.61e-1)" "unprognostic (3.53e-2)" "unprognostic (4.36e-1)" "unprognostic (7.41e-2)" "unprognostic (3.97e-2)" "unprognostic (9.28e-2)" "unprognostic (3.18e-1)" "unprognostic (5.11e-2)" "unprognostic (3.19e-2)" "unprognostic (1.99e-2)" "unprognostic (3.15e-1)" "unprognostic (6.15e-2)" "unprognostic (1.32e-1)" "unprognostic (1.96e-1)" "unprognostic (2.64e-2)" "unprognostic (9.54e-2)" "unprognostic (2.03e-2)" "unprognostic (7.96e-2)" "unprognostic (1.08e-2)" "unprognostic (1.75e-1)" "unprognostic (7.73e-2)" "unprognostic (2.38e-1)" "unprognostic (1.63e-1)" "unprognostic (4.22e-2)" "unprognostic (1.42e-1)" SYTL4 ENSG00000102362 "Synaptotagmin like 4" Q96C24 X 100671783-100732123 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 40.0;ovary: 49.2" "Cell type enhanced" "Detected in many" "Corticotrophs: 350.5;Gonadotrophs: 439.2;Leydig cells: 200.7;Ovarian stromal cells: 209.8;Platelets: 233.9;Sertoli cells: 188.5;Somatotrophs: 584.9;Thyrotrophs: 432.1" "Cell type enhanced" "Detected in many" "astrocyte: 145.5;Bergmann glia: 66.2;fibroblast: 100.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.6" "Lineage enriched" "Detected in single" 10 "granulocytes: 1.6" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts" "Region enriched" "Detected in many" 5 "hypothalamus: 30.1" "Low region specificity" "Detected in all" "HPA001475, HPA001589, HPA075138" Approved Approved Vesicles NA Yes 2000000 "Cluster 35: Neutrophils - Protein binding" "Cluster 75: Ovary - Mixed function" "Cluster 46: Brainstem - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 39 Vesicles "HPA001475: , HPA001589: , HPA075138: " "unprognostic (1.89e-2)" "unprognostic (1.56e-2)" "unprognostic (3.95e-2)" "unprognostic (1.99e-1)" "unprognostic (9.06e-2)" "unprognostic (2.34e-2)" "unprognostic (1.70e-1)" "unprognostic (8.88e-2)" "unprognostic (3.02e-1)" "unprognostic (4.11e-1)" "unprognostic (1.45e-3)" "unprognostic (1.07e-1)" "unprognostic (1.67e-1)" "unprognostic (4.23e-2)" "unprognostic (4.28e-3)" "unprognostic (1.38e-1)" "unprognostic (6.42e-2)" "unprognostic (5.91e-2)" "unprognostic (4.78e-2)" "unprognostic (9.23e-2)" "unprognostic (4.74e-2)" "unprognostic (2.59e-3)" "unprognostic (2.28e-1)" "unprognostic (2.37e-1)" "unprognostic (1.10e-2)" "unprognostic (1.24e-1)" "unprognostic (8.30e-2)" "unprognostic (4.03e-2)" "unprognostic (3.10e-1)" "unprognostic (1.11e-1)" SYTL5 ENSG00000147041 "Synaptotagmin like 5" Q8TDW5 X 38006553-38128819 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.9;stomach 1: 11.4" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 54.9;Brain inhibitory neurons: 112.4;Esophageal apical cells: 38.9;Foveolar cells: 227.0;Goblet cells: 102.1;Gonadotrophs: 44.6;Other brain neurons: 42.8;Salivary duct cells: 50.7" "Cell type enhanced" "Detected in many" "eccentric medium spiny neuron: 237.8;LAMP5-LHX6 and Chandelier: 152.0;medium spiny neuron: 201.9;MGE interneuron: 143.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 18.0" "Breast - Breast glandular cells, Stomach - Gastric mucous cells, Testis - Peritubular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA001424, HPA026074" Uncertain Approved "Golgi apparatus,Cytosol" NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 29: Forebrain - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 35: Neurons - Synaptic function & neurogenesis" 8 "Golgi apparatus, Cytosol" "HPA001424: , HPA026074: " "unprognostic (5.92e-2)" "unprognostic (7.52e-2)" "unprognostic (4.39e-1)" "unprognostic (2.22e-2)" "unprognostic (1.08e-1)" "unprognostic (5.04e-2)" "unprognostic (1.53e-2)" "unprognostic (7.23e-2)" "unprognostic (1.76e-1)" "unprognostic (2.20e-1)" "unprognostic (5.40e-2)" "unprognostic (1.19e-1)" "unprognostic (2.96e-1)" "unprognostic (6.99e-2)" "unprognostic (2.19e-1)" "unprognostic (1.10e-1)" "potential prognostic unfavorable (5.59e-4)" "unprognostic (9.08e-2)" "unprognostic (1.71e-2)" "unprognostic (1.55e-1)" "unprognostic (1.17e-2)" SYVN1 "DER3, HRD1" ENSG00000162298 "Synoviolin 1" Q86TM6 11 65121780-65134532 "Disease related genes, Enzymes, Essential proteins, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Stress response, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 90.2;Plasma cells: 97.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005480, HPA024300, CAB037030" Enhanced Supported "Nucleoplasm,Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 6: Non-specific - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 44: Plasma cells - Antibody production & secretion" 74 Nucleoplasm "Endoplasmic reticulum, Plasma membrane" "CAB037030: , HPA005480: , HPA024300: " "unprognostic (1.76e-1)" "unprognostic (2.31e-2)" "unprognostic (2.15e-1)" "unprognostic (3.66e-3)" "unprognostic (9.28e-2)" "unprognostic (3.61e-1)" "unprognostic (1.65e-1)" "unprognostic (5.95e-2)" "unprognostic (7.70e-2)" "unprognostic (3.34e-3)" "potential prognostic favorable (4.70e-4)" "unprognostic (3.89e-1)" "unprognostic (3.48e-1)" "unprognostic (1.37e-1)" "unprognostic (2.23e-2)" "unprognostic (2.58e-1)" "unprognostic (2.96e-1)" "unprognostic (2.16e-2)" "unprognostic (9.80e-2)" "unprognostic (1.28e-1)" "unprognostic (1.55e-2)" "unprognostic (1.86e-1)" "unprognostic (1.01e-2)" "unprognostic (2.57e-2)" "unprognostic (1.84e-1)" "unprognostic (3.22e-1)" "unprognostic (1.93e-1)" "unprognostic (5.20e-2)" "unprognostic (6.88e-2)" "unprognostic (6.29e-2)" "unprognostic (2.41e-1)" SZRD1 "C1orf144, DKFZp566C0424" ENSG00000055070 "SUZ RNA binding domain containing 1" Q7Z422 1 16352575-16398145 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 204.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024221 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 2 "Nucleoplasm, Cytosol" "HPA024221: " "unprognostic (3.93e-2)" "unprognostic (3.70e-1)" "unprognostic (2.25e-1)" "unprognostic (1.13e-2)" "unprognostic (3.32e-2)" "unprognostic (9.90e-2)" "unprognostic (1.31e-1)" "unprognostic (1.71e-1)" "unprognostic (1.24e-1)" "potential prognostic favorable (4.42e-4)" "unprognostic (2.46e-2)" "unprognostic (9.80e-2)" "potential prognostic unfavorable (1.86e-8)" "unprognostic (1.55e-1)" "unprognostic (3.03e-3)" "unprognostic (9.66e-2)" "unprognostic (2.04e-1)" "unprognostic (3.45e-2)" "unprognostic (3.98e-1)" "unprognostic (2.44e-1)" "unprognostic (1.34e-1)" "unprognostic (2.25e-2)" "unprognostic (2.50e-2)" "unprognostic (2.33e-2)" "unprognostic (2.71e-1)" "unprognostic (3.56e-1)" "unprognostic (1.63e-1)" "unprognostic (1.38e-1)" "unprognostic (1.12e-1)" SZT2 "C1orf84, FLJ10387, FLJ34502, KIAA0467, KICS1, RP11-506B15.1, SZT2A, SZT2B" ENSG00000198198 "SZT2 subunit of KICSTOR complex" Q5T011 1 43389882-43454247 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 116.0;Epicardial cells: 168.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029012 Approved Approved "Nucleoplasm,Vesicles,Actin filaments" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 49: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 37: Non-specific - mRNA processing" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 20 "Nucleoplasm, Vesicles, Actin filaments" "HPA029012: " "unprognostic (5.59e-2)" "unprognostic (2.60e-1)" "unprognostic (7.41e-2)" "unprognostic (2.17e-1)" "unprognostic (2.75e-1)" "unprognostic (2.62e-2)" "unprognostic (1.76e-1)" "unprognostic (2.00e-3)" "potential prognostic unfavorable (9.74e-4)" "potential prognostic favorable (7.30e-6)" "unprognostic (1.40e-2)" "unprognostic (4.19e-2)" "unprognostic (2.73e-1)" "unprognostic (7.28e-3)" "unprognostic (4.18e-2)" "unprognostic (1.94e-1)" "unprognostic (3.10e-1)" "unprognostic (8.08e-2)" "unprognostic (1.37e-2)" "unprognostic (9.84e-2)" "unprognostic (5.54e-3)" "unprognostic (1.06e-1)" "unprognostic (5.95e-3)" "unprognostic (2.17e-3)" "unprognostic (3.72e-2)" "unprognostic (5.36e-2)" "unprognostic (1.96e-1)" "unprognostic (1.05e-2)" "unprognostic (4.84e-3)" TAAR1 "TA1, TAR1, TRAR1" ENSG00000146399 "Trace amine associated receptor 1" Q96RJ0 6 132643312-132659182 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 6 "stomach 1: 4.7" "Group enriched" "Detected in some" 4 "Fallopian tube ciliated cells: 11.4;Neuroendocrine cells: 4.2;Neutrophils: 6.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "pancreatic cancer: 2.1" "Not detected" "Not detected" HPA055614 Approved NA NA "Cluster 60: Stomach - Digestion" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 24: Neutrophils - Innate immunity signal integration" "HPA055614: " "unprognostic (2.97e-1)" TAAR2 GPR58 ENSG00000146378 "Trace amine associated receptor 2" Q9P1P5 6 132617022-132624275 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Early spermatids: 6.4;Late spermatids: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" TAAR5 PNR ENSG00000135569 "Trace amine associated receptor 5" O14804 6 132588592-132589741 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA051703 Uncertain NA NA "HPA051703: " TAAR6 "TA4, TRAR4" ENSG00000146383 "Trace amine associated receptor 6" Q96RI8 6 132570322-132571359 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 11: Neuronal - Sensory perception" TAAR8 "GPR102, TA5, TAR5, TRAR5" ENSG00000146385 "Trace amine associated receptor 8" Q969N4 6 132552672-132553756 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 11: Neuronal - Sensory perception" TAAR9 "TA3, TAR3, TRAR3" ENSG00000237110 "Trace amine associated receptor 9" Q96RI9 6 132538277-132539336 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 15: Kidney cancer - Membrane components" 1 TAB1 MAP3K7IP1 ENSG00000100324 "TGF-beta activated kinase 1 (MAP3K7) binding protein 1" Q15750 22 39399778-39437060 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 74.5;Retinal bipolar cells: 125.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032328, HPA039988, HPA057104" Approved NA NA 4500 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 64: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 66: Non-specific - Mitochondria" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 65 "CAB032328: , HPA039988: , HPA057104: " "unprognostic (2.13e-2)" "unprognostic (2.78e-1)" "unprognostic (3.65e-2)" "unprognostic (2.37e-1)" "unprognostic (2.32e-1)" "unprognostic (2.21e-2)" "unprognostic (7.74e-2)" "unprognostic (7.50e-2)" "unprognostic (1.19e-2)" "unprognostic (5.72e-3)" "potential prognostic favorable (1.86e-4)" "unprognostic (2.30e-2)" "potential prognostic favorable (6.67e-6)" "unprognostic (3.02e-2)" "unprognostic (1.64e-1)" "unprognostic (2.32e-2)" "unprognostic (1.61e-1)" "unprognostic (3.94e-2)" "unprognostic (1.50e-2)" "unprognostic (4.80e-2)" "unprognostic (1.93e-1)" "unprognostic (3.57e-1)" "unprognostic (2.55e-1)" "unprognostic (2.99e-1)" "unprognostic (1.30e-2)" "unprognostic (4.29e-2)" "unprognostic (1.50e-1)" "unprognostic (1.45e-1)" "unprognostic (2.25e-1)" "unprognostic (4.95e-2)" "unprognostic (2.18e-2)" TAB2 "KIAA0733, MAP3K7IP2" ENSG00000055208 "TGF-beta activated kinase 1 (MAP3K7) binding protein 2" Q9NYJ8 6 149218641-149411613 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglia: 616.6;Neutrophils: 798.0" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 782.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065436, HPA070137" Approved NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 73 "HPA065436: , HPA070137: " "unprognostic (7.75e-2)" "unprognostic (2.05e-3)" "potential prognostic unfavorable (6.18e-5)" "unprognostic (1.61e-3)" "unprognostic (3.80e-2)" "unprognostic (1.12e-1)" "unprognostic (1.55e-1)" "unprognostic (3.58e-2)" "unprognostic (1.02e-1)" "unprognostic (9.88e-2)" "potential prognostic favorable (1.29e-6)" "unprognostic (3.51e-2)" "unprognostic (8.33e-2)" "unprognostic (5.65e-3)" "unprognostic (2.00e-1)" "unprognostic (9.31e-2)" "unprognostic (3.29e-2)" "unprognostic (9.19e-3)" "unprognostic (2.18e-1)" "unprognostic (8.06e-3)" "unprognostic (7.01e-2)" "unprognostic (3.30e-2)" "unprognostic (6.11e-3)" "unprognostic (1.46e-1)" "unprognostic (2.30e-1)" "unprognostic (2.60e-1)" "unprognostic (1.67e-1)" "unprognostic (1.10e-1)" "unprognostic (8.39e-2)" "unprognostic (3.27e-1)" "unprognostic (1.52e-1)" TAB3 MAP3K7IP3 ENSG00000157625 "TGF-beta activated kinase 1 (MAP3K7) binding protein 3" Q8N5C8 X 30827442-30975084 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Choroid plexus epithelial cells: 208.6;Esophageal apical cells: 138.6;Sertoli cells: 258.5" "Cell type enriched" "Detected in all" 4 "choroid plexus epithelial cell: 187.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034980, HPA034981" Approved Approved "Nuclear speckles,Cytosol" NA NA "Cluster 42: Retina - Visual perception" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 19 "Nuclear speckles, Cytosol" "HPA034980: , HPA034981: " "unprognostic (3.45e-1)" "unprognostic (1.93e-1)" "unprognostic (5.67e-2)" "unprognostic (2.70e-1)" "unprognostic (4.01e-2)" "unprognostic (1.95e-1)" "unprognostic (1.66e-1)" "unprognostic (2.53e-1)" "unprognostic (6.03e-3)" "unprognostic (6.23e-3)" "potential prognostic favorable (2.33e-4)" "unprognostic (1.08e-1)" "unprognostic (2.81e-1)" "unprognostic (5.89e-3)" "unprognostic (2.48e-1)" "unprognostic (1.12e-1)" "unprognostic (4.84e-2)" "unprognostic (1.66e-1)" "unprognostic (1.08e-1)" "unprognostic (1.78e-1)" "unprognostic (1.69e-2)" "unprognostic (2.31e-1)" "unprognostic (1.92e-2)" "unprognostic (2.52e-1)" "unprognostic (3.43e-2)" "unprognostic (2.25e-1)" "unprognostic (1.79e-1)" "unprognostic (7.13e-2)" "unprognostic (5.76e-2)" "unprognostic (8.77e-2)" "unprognostic (1.97e-1)" TAC1 "NKNA, NPK, TAC2" ENSG00000006128 "Tachykinin precursor 1" P20366 7 97732084-97740472 "Predicted secreted proteins" "Neuropeptide, Neurotransmitter" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 223.0" "Cell type enriched" "Detected in some" 4 "Pancreatic acinar cells: 728.8" "Group enriched" "Detected in many" 4 "eccentric medium spiny neuron: 293.8;LAMP5-LHX6 and Chandelier: 198.8;mammillary body: 307.5;medium spiny neuron: 232.6;MGE interneuron: 371.5;splatter: 135.8" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 12.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "skin cancer: 8.5" "Region enhanced" "Detected in all" "basal ganglia: 560.0" "Region enriched" "Detected in all" 10 "basal ganglia: 511.9" HPA014429 Enhanced "Secreted to blood" Neuropeptide NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 69: Skin cancer - ECM organization" "Cluster 98: Neurons - Neurotransmission & signaling" 3 "HPA014429: " "unprognostic (2.45e-1)" "unprognostic (1.04e-3)" "unprognostic (2.81e-1)" "unprognostic (3.63e-2)" "unprognostic (1.32e-1)" "unprognostic (6.49e-3)" "unprognostic (3.04e-1)" "unprognostic (2.37e-1)" "unprognostic (3.49e-1)" "unprognostic (4.07e-1)" "unprognostic (2.70e-1)" "unprognostic (1.86e-1)" "unprognostic (9.84e-3)" "unprognostic (4.00e-1)" "unprognostic (4.94e-2)" "unprognostic (1.40e-1)" "unprognostic (2.76e-2)" "unprognostic (2.25e-1)" TAC3 "LncZBTB39, LncZBTB39-1:2, NK3, NKB, NKNB, ZNEUROK1" ENSG00000166863 "Tachykinin precursor 3" Q9UHF0 12 57010000-57028883 "Disease related genes, Human disease related genes, Predicted secreted proteins" Neuropeptide "Disease variant, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "placenta: 404.6" "Cell type enhanced" "Detected in some" "Brain inhibitory neurons: 28.3;Colonocytes: 19.8;Cytotrophoblasts: 11.8;Enteric stem cells: 13.4;Enteric transient amplifying cells: 22.4;Enterocytes: 106.5;Extravillous trophoblasts: 23.1;Goblet cells: 16.9;Migrating cytotrophoblasts: 12.5;Neuroendocrine cells: 10.2;Other brain neurons: 16.6;Paneth cells: 11.6;Syncytiotrophoblasts: 22.6" "Cell type enhanced" "Detected in some" "CGE interneuron: 111.6;MGE interneuron: 38.6" "Cancer enriched" "Detected in many" 5 "Bladder Urothelial Carcinoma (TCGA): 93.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "testis cancer: 12.4" "Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA045919 Supported Supported Approved Vesicles "Secreted in female reproductive system" Neuropeptide NA NA 55000 "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 34: Testis cancer - Unknown function" "Cluster 1: Enterocytes - Absorption and Digestion" 6 Vesicles "HPA045919: " "unprognostic (2.01e-1)" "unprognostic (1.67e-1)" "unprognostic (3.61e-2)" "unprognostic (8.58e-2)" "unprognostic (5.90e-2)" "unprognostic (7.87e-2)" "unprognostic (1.89e-1)" "unprognostic (7.66e-2)" "unprognostic (1.35e-1)" "unprognostic (3.49e-1)" "unprognostic (6.74e-3)" "unprognostic (3.19e-1)" TAC4 "HK-1, PPT-C, Pptc" ENSG00000176358 "Tachykinin precursor 4" Q86UU9 17 49838300-49848069 "Predicted secreted proteins" "Hypotensive agent" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 2.5;pituitary gland: 5.1" "Cell type enhanced" "Detected in many" "Epicardial cells: 25.0;Myonuclei: 16.8;Retinal bipolar cells: 15.3;Retinal ganglion cells: 19.3;Tuft cells: 23.1" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Glioblastoma Multiforme (TCGA): 1.6;Lung Adenocarcinoma (TCGA): 5.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Rhabdoid: 6.5" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" Other NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 48: Non-specific - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "unprognostic (9.02e-3)" "unprognostic (2.55e-1)" "unprognostic (5.25e-2)" "unprognostic (1.76e-2)" "unprognostic (6.31e-3)" "unprognostic (1.45e-1)" "unprognostic (9.93e-3)" TACC1 ENSG00000147526 "Transforming acidic coiled-coil containing protein 1" O75410 8 38728186-38853028 "Predicted intracellular proteins" "Cell cycle, Cell division" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 749.1;Pericytes: 1025.6;Pituicytes/FSCs: 1099.6;Vascular endothelial cells: 945.1;Vascular smooth muscle cells: 928.5" "Cell type enhanced" "Detected in all" "endothelial cell: 1364.5;vascular associated smooth muscle cell: 944.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 33.3;granulocytes: 31.1;monocytes: 14.0" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Prostate - Smooth muscle cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017041, HPA024702, HPA056841" Approved Approved Cytosol NA NA 21000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 11: White matter - Signal transduction" "Cluster 55: Lymphoma - Immune response" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 36 Cytosol "CAB017041: , HPA024702: , HPA056841: " "unprognostic (2.05e-3)" "unprognostic (1.02e-1)" "unprognostic (3.78e-2)" "unprognostic (3.05e-1)" "unprognostic (1.27e-1)" "unprognostic (7.29e-2)" "unprognostic (2.08e-1)" "unprognostic (2.21e-1)" "unprognostic (6.36e-2)" "unprognostic (1.11e-1)" "validated prognostic favorable (2.70e-9)" "validated prognostic favorable (1.16e-6)" "unprognostic (3.77e-1)" "unprognostic (2.40e-1)" "unprognostic (2.86e-2)" "unprognostic (1.77e-1)" "unprognostic (9.04e-2)" "unprognostic (3.39e-1)" "unprognostic (6.75e-2)" "unprognostic (6.81e-3)" "unprognostic (3.41e-3)" "unprognostic (3.08e-2)" "unprognostic (3.00e-2)" "unprognostic (2.86e-2)" "unprognostic (3.93e-1)" "unprognostic (9.78e-2)" "unprognostic (1.01e-1)" "potential prognostic unfavorable (4.19e-4)" "unprognostic (1.89e-1)" "unprognostic (4.76e-1)" "unprognostic (1.70e-1)" TACC2 "AZU-1, ECTACC" ENSG00000138162 "Transforming acidic coiled-coil containing protein 2" O95359 10 121989163-122254545 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 238.7;skeletal muscle: 371.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 680.5;Alveolar cells type 2: 2199.3;Cardiomyocytes: 929.3;Myonuclei: 1541.2;Syncytiotrophoblasts: 1526.8;Transitional alveolar cells: 1001.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2, Skin - Keratinocyte (other), Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031020, HPA031021, HPA061394" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 13000 "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 23: Choroid plexus - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 12 "Nucleoplasm, Cytosol" "Plasma membrane" "HPA031020: , HPA031021: , HPA061394: " "unprognostic (6.37e-3)" "unprognostic (1.32e-2)" "unprognostic (1.91e-1)" "unprognostic (1.11e-1)" "unprognostic (1.02e-1)" "unprognostic (8.27e-2)" "unprognostic (1.31e-1)" "unprognostic (1.52e-2)" "unprognostic (8.76e-2)" "unprognostic (4.45e-1)" "unprognostic (1.17e-3)" "unprognostic (6.22e-3)" "unprognostic (2.09e-3)" "unprognostic (3.92e-3)" "unprognostic (8.30e-2)" "unprognostic (1.96e-1)" "unprognostic (4.44e-2)" "unprognostic (3.59e-3)" "unprognostic (8.07e-3)" "unprognostic (3.07e-1)" "unprognostic (1.25e-3)" "unprognostic (2.05e-2)" "unprognostic (2.07e-1)" "unprognostic (9.50e-2)" "unprognostic (1.33e-1)" "unprognostic (1.10e-1)" "unprognostic (3.54e-2)" "unprognostic (6.14e-1)" "unprognostic (5.73e-2)" "unprognostic (8.72e-3)" "unprognostic (6.97e-2)" TACC3 "ERIC-1, ERIC1, maskin, Tacc4" ENSG00000013810 "Transforming acidic coiled-coil containing protein 3" Q9Y6A5 4 1712858-1745171 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 53.1;lymphoid tissue: 48.0;testis: 54.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 148.1;Early spermatids: 113.3;Erythrocyte progenitors: 117.7;Late primary spermatocytes: 224.2;Late spermatids: 154.5;Megakaryocytes: 197.8;Monocyte progenitors: 201.6;Neutrophil progenitors: 101.5;Neutrophils: 186.2;Oocytes: 179.6;Platelets: 255.4" "Cell type enhanced" "Detected in all" "leukocyte: 28.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 91.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005781, HPA006050, CAB010111, HPA022039" Enhanced Approved "Golgi apparatus,Mitotic spindle,Centriolar satellite,Basal body,Cytosol" Yes Yes "Cluster 35: Neutrophils - Protein binding" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 23: Choroid plexus - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Non-specific - Cell proliferation" 39 "Centriolar satellite, Cytosol" "Golgi apparatus, Mitotic spindle, Basal body" "CAB010111: , HPA005781: , HPA006050: , HPA022039: " "unprognostic (1.05e-1)" "unprognostic (1.51e-1)" "unprognostic (8.50e-2)" "unprognostic (4.78e-2)" "unprognostic (4.75e-2)" "unprognostic (2.12e-1)" "unprognostic (1.87e-1)" "unprognostic (1.91e-1)" "unprognostic (1.08e-1)" "potential prognostic unfavorable (8.99e-4)" "validated prognostic unfavorable (1.11e-9)" "validated prognostic unfavorable (1.36e-5)" "potential prognostic unfavorable (1.80e-5)" "validated prognostic unfavorable (1.35e-5)" "validated prognostic unfavorable (3.08e-6)" "validated prognostic unfavorable (8.27e-8)" "validated prognostic unfavorable (3.77e-4)" "unprognostic (6.23e-3)" "unprognostic (7.59e-2)" "unprognostic (1.51e-1)" "unprognostic (2.78e-3)" "unprognostic (1.63e-2)" "unprognostic (3.57e-2)" "unprognostic (1.39e-2)" "unprognostic (1.25e-1)" "unprognostic (4.21e-1)" "unprognostic (3.94e-3)" "unprognostic (1.61e-1)" "unprognostic (3.41e-1)" "unprognostic (1.83e-3)" "unprognostic (7.59e-2)" TACO1 CCDC44 ENSG00000136463 "Translational activator of cytochrome c oxidase I" Q9BSH4 17 63600882-63608365 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Translation regulation" Activator "Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 16.5;Enteric stem cells: 14.2;Enteric transient amplifying cells: 20.7;Enterocytes: 35.1;Paneth cells: 15.5;Parietal cells: 14.1;Tuft cells: 11.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021626, HPA021643, HPA024294" Enhanced Enhanced Mitochondria NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 76: Non-specific - Metabolism" "Cluster 45: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 15: Non-specific - Protein processing" 22 Mitochondria "HPA021626: , HPA021643: , HPA024294: " "unprognostic (4.54e-2)" "unprognostic (7.37e-3)" "potential prognostic unfavorable (7.53e-4)" "unprognostic (3.26e-1)" "unprognostic (4.21e-3)" "unprognostic (2.21e-1)" "unprognostic (1.27e-1)" "unprognostic (1.36e-1)" "unprognostic (5.38e-3)" "unprognostic (3.68e-2)" "unprognostic (1.44e-3)" "unprognostic (3.60e-1)" "unprognostic (6.30e-3)" "unprognostic (2.12e-1)" "unprognostic (9.75e-3)" "potential prognostic unfavorable (5.78e-4)" "unprognostic (2.36e-3)" "unprognostic (3.08e-1)" "unprognostic (1.04e-2)" "unprognostic (5.64e-2)" "unprognostic (1.26e-1)" "unprognostic (1.36e-3)" "unprognostic (1.67e-1)" "unprognostic (5.94e-2)" "unprognostic (5.68e-2)" "unprognostic (6.52e-2)" "unprognostic (3.09e-1)" "unprognostic (2.26e-1)" "unprognostic (3.07e-1)" "unprognostic (2.78e-1)" "unprognostic (4.26e-2)" TACR1 "NK1R, NKIR, SPR, TAC1R" ENSG00000115353 "Tachykinin receptor 1" P25103 2 75046463-75199520 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 6.2" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 60.4;Cone photoreceptor cells: 161.5;Epicardial cells: 341.1;Other brain neurons: 176.7;Retinal amacrine cells: 96.6;Rod photoreceptor cells: 271.4;Vascular endothelial cells: 153.6" "Cell type enhanced" "Detected in all" "eccentric medium spiny neuron: 156.4;LAMP5-LHX6 and Chandelier: 305.0;splatter: 155.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 23 "basophil: 2.2" "Lineage enriched" "Detected in single" 23 "granulocytes: 2.2" "Group enriched" "Detected in some" 4 "Brain cancer: 2.9;ovarian cancer: 1.2" "Breast - Endothelial cells, Minor Salivary Gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA055565, HPA074573" Enhanced Approved "Plasma membrane,Centrosome,Basal body" NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 72: Neuronal - Signal transduction" "Cluster 109: Neurons - Neuronal signaling" 14 "Plasma membrane, Centrosome, Basal body" "HPA055565: , HPA074573: " "potential prognostic favorable (7.18e-4)" "unprognostic (4.16e-2)" "unprognostic (7.10e-2)" "potential prognostic favorable (1.96e-4)" "unprognostic (4.07e-1)" "unprognostic (1.18e-1)" "unprognostic (1.84e-3)" TACR2 "NK2R, NKNAR, SKR, TAC2R" ENSG00000075073 "Tachykinin receptor 2" P21452 10 69403903-69416918 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 134.1" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 9.7;Epicardial cells: 6.8;Hepatic stellate cells: 6.5;Retinal horizontal cells: 10.0;Smooth muscle cells: 43.6;Tuft cells: 11.5" "Cell type enhanced" "Detected in single" "hippocampal CA4: 1.9" "Cancer enhanced" "Detected in many" "Stomach Adenocarcinoma (TCGA): 11.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "intermediate monocyte: 1.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in some" "Prostate - Smooth muscle cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA076573 Supported "Plasma membrane" NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 51: Neurons - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 62: Smooth muscle cells - Muscle contraction" 1 "Plasma membrane" "HPA076573: " "unprognostic (1.38e-1)" "unprognostic (5.33e-2)" "unprognostic (1.60e-1)" "potential prognostic favorable (3.82e-4)" "unprognostic (4.01e-1)" "unprognostic (2.36e-2)" "unprognostic (8.34e-3)" "unprognostic (8.39e-3)" "unprognostic (9.09e-2)" "unprognostic (3.03e-2)" "unprognostic (9.78e-2)" "unprognostic (9.89e-3)" "potential prognostic favorable (1.76e-4)" "unprognostic (6.06e-2)" "unprognostic (8.70e-2)" "unprognostic (4.76e-2)" "unprognostic (1.17e-3)" "unprognostic (7.28e-3)" "unprognostic (3.18e-2)" TACR3 "NK3R, NKR, TAC3R" ENSG00000169836 "Tachykinin receptor 3" P29371 4 103586031-103719985 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 1.2;retina: 2.5;urinary bladder: 1.7" "Cell type enhanced" "Detected in some" "Extravillous trophoblasts: 11.6;Myosatellite cells: 80.8;Oligodendrocytes: 12.8;Other brain neurons: 26.0;Podocytes: 90.9;Retinal bipolar cells: 78.4;Thyrotrophs: 18.5" "Cell type enhanced" "Detected in many" "amygdala excitatory: 32.1;hippocampal CA1-3: 66.1;splatter: 28.5" "Not detected" "Not detected" "Region enhanced" "Detected in many" "pons: 18.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 21 "Sarcoma: 2.9" "Kidney - Podocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA009418 Uncertain NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 54: Non-specific - Transcription" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "HPA009418: " TACSTD2 "EGP-1, GA733-1, M1S1, TROP2" ENSG00000184292 "Tumor associated calcium signal transducer 2" P09758 1 58575433-58577252 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" "Sensory transduction, Vision" "Tumor antigen" "Amyloidosis, Corneal dystrophy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 1245.4;salivary gland: 585.3;skin 1: 554.9" "Cell type enhanced" "Detected in many" "Breast secretory cells: 1810.4;Epididymal basal cells: 7482.4;Esophageal apical cells: 17505.8;Esophageal basal cells: 2063.6;Esophageal suprabasal cells: 5347.3;Ocular epithelial cells: 3288.3;Suprabasal keratinocytes: 2163.4" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 4 "choroid plexus: 3.9;white matter: 1.1" "Immune cell enhanced" "Detected in some" "eosinophil: 15.1" "Group enriched" "Detected in many" 79 "dendritic cells: 4.3;granulocytes: 15.1;monocytes: 4.2" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 603.0;head and neck cancer: 792.6" "Liver - Cholangiocytes, Pancreas - Ductal cells, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA043104, HPA055067, CAB072852" Enhanced Supported "Nucleoli,Vesicles,Plasma membrane" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 6 "Plasma membrane" "Nucleoli, Vesicles" "CAB072852: , HPA043104: , HPA055067: " "unprognostic (1.45e-1)" "unprognostic (5.10e-2)" "unprognostic (7.09e-2)" "unprognostic (2.30e-1)" "unprognostic (1.42e-1)" "unprognostic (1.24e-1)" "unprognostic (6.81e-2)" "potential prognostic favorable (7.73e-5)" "unprognostic (8.69e-2)" "unprognostic (1.52e-1)" "unprognostic (4.31e-2)" "unprognostic (1.37e-1)" "unprognostic (1.21e-2)" "unprognostic (5.84e-2)" "unprognostic (2.56e-2)" "unprognostic (6.29e-2)" "unprognostic (1.62e-3)" "unprognostic (1.61e-2)" "unprognostic (9.31e-2)" "unprognostic (1.34e-2)" "unprognostic (3.26e-1)" "unprognostic (3.51e-1)" "unprognostic (4.11e-1)" "unprognostic (1.58e-1)" "unprognostic (2.05e-1)" "unprognostic (1.43e-1)" "unprognostic (3.42e-1)" "unprognostic (1.49e-2)" "unprognostic (8.16e-2)" TADA1 "ADA1, hADA1, HFI1, STAF42, TADA1L" ENSG00000152382 "Transcriptional adaptor 1" Q96BN2 1 166856510-166876264 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 46.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028651 Approved Supported "Nucleoplasm,Focal adhesion sites,Cytosol" No No "Cluster 3: Non-specific - Nuclear processes" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 31: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 51 Nucleoplasm "Focal adhesion sites, Cytosol" "HPA028651: " "unprognostic (1.61e-2)" "unprognostic (5.02e-3)" "unprognostic (4.45e-2)" "unprognostic (5.42e-2)" "unprognostic (3.69e-2)" "unprognostic (2.82e-1)" "unprognostic (2.05e-1)" "unprognostic (3.17e-1)" "unprognostic (5.01e-2)" "potential prognostic unfavorable (4.54e-7)" "potential prognostic favorable (3.73e-6)" "unprognostic (4.34e-2)" "unprognostic (1.86e-2)" "unprognostic (1.42e-2)" "unprognostic (6.33e-3)" "unprognostic (1.09e-1)" "unprognostic (8.04e-3)" "unprognostic (9.45e-2)" "unprognostic (1.45e-1)" "unprognostic (1.32e-1)" "unprognostic (2.37e-2)" "unprognostic (1.23e-1)" "unprognostic (2.85e-1)" "unprognostic (4.55e-2)" "unprognostic (6.04e-2)" "unprognostic (6.60e-2)" "unprognostic (1.15e-1)" "unprognostic (1.02e-1)" "unprognostic (4.81e-2)" "unprognostic (4.50e-2)" "unprognostic (6.72e-2)" TADA2A "ADA2, ADA2A, hADA2, TADA2L" ENSG00000276234 "Transcriptional adaptor 2A" 17 37406886-37479725 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 34.7;Late spermatids: 52.4;Microglia: 42.2;Renal collecting duct intercalated cells: 42.4;Renal collecting duct principal cells: 37.6;Renal connecting tubule cells: 38.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076497 Approved "Nuclear speckles" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 67: Testis - Mixed function" "Cluster 34: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 102: Non-specific - Mixed function" 24 "Nuclear speckles" "HPA076497: " "unprognostic (5.37e-2)" "unprognostic (5.31e-2)" "unprognostic (2.02e-1)" "unprognostic (1.65e-1)" "unprognostic (2.89e-1)" "unprognostic (2.23e-1)" "unprognostic (9.79e-2)" "unprognostic (4.63e-2)" "unprognostic (1.70e-3)" "unprognostic (7.91e-3)" "unprognostic (5.20e-2)" "unprognostic (2.22e-1)" "unprognostic (2.47e-2)" "unprognostic (9.87e-2)" "unprognostic (5.55e-2)" "unprognostic (1.01e-1)" "unprognostic (2.72e-1)" "unprognostic (2.62e-1)" "unprognostic (4.77e-3)" "unprognostic (2.20e-2)" "unprognostic (2.60e-1)" "unprognostic (1.02e-1)" "unprognostic (2.74e-1)" "unprognostic (9.92e-2)" "unprognostic (1.63e-1)" "unprognostic (1.49e-1)" "unprognostic (2.71e-3)" "unprognostic (1.64e-1)" TADA2B MGC21874 ENSG00000173011 "Transcriptional adaptor 2B" Q86TJ2 4 7041899-7057952 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 78.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035770 Approved Approved "Nuclear speckles" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 62 "Nuclear speckles" "HPA035770: " "potential prognostic favorable (5.27e-4)" "unprognostic (2.86e-1)" "unprognostic (7.65e-2)" "unprognostic (1.53e-1)" "unprognostic (5.12e-3)" "unprognostic (4.24e-1)" "unprognostic (9.93e-2)" "unprognostic (2.69e-3)" "unprognostic (8.52e-3)" "unprognostic (3.51e-2)" "validated prognostic favorable (4.18e-8)" "validated prognostic favorable (1.31e-5)" "potential prognostic favorable (2.65e-4)" "unprognostic (1.08e-1)" "unprognostic (7.08e-2)" "unprognostic (1.22e-1)" "unprognostic (7.39e-2)" "unprognostic (7.29e-3)" "unprognostic (2.85e-1)" "unprognostic (2.68e-1)" "unprognostic (2.04e-1)" "unprognostic (6.46e-2)" "unprognostic (2.75e-1)" "unprognostic (1.46e-1)" "unprognostic (3.01e-2)" "unprognostic (1.52e-2)" "unprognostic (3.16e-1)" "unprognostic (1.17e-1)" "unprognostic (2.31e-1)" "unprognostic (2.44e-1)" "unprognostic (9.18e-2)" TADA3 "ADA3, FLJ20221, FLJ21329, hADA3, NGG1, TADA3L" ENSG00000171148 "Transcriptional adaptor 3" O75528 3 9779967-9793011 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 163.1;Megakaryocytes: 222.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042250 Approved Supported Nucleoplasm NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 47: Platelets - Hemostasis" 72 Nucleoplasm "HPA042250: " "unprognostic (5.03e-2)" "unprognostic (1.60e-1)" "unprognostic (3.68e-2)" "unprognostic (6.02e-2)" "unprognostic (6.31e-2)" "unprognostic (1.62e-2)" "unprognostic (1.08e-1)" "unprognostic (1.96e-2)" "unprognostic (8.44e-2)" "potential prognostic unfavorable (3.44e-4)" "potential prognostic favorable (8.67e-4)" "unprognostic (1.25e-1)" "unprognostic (1.65e-2)" "validated prognostic unfavorable (1.39e-4)" "validated prognostic unfavorable (2.47e-5)" "unprognostic (1.73e-1)" "unprognostic (7.53e-3)" "unprognostic (3.28e-2)" "unprognostic (2.36e-1)" "unprognostic (8.02e-2)" "unprognostic (5.69e-2)" "unprognostic (4.35e-1)" "unprognostic (3.00e-1)" "unprognostic (1.30e-1)" "unprognostic (1.31e-2)" "unprognostic (9.30e-2)" "unprognostic (3.70e-1)" "unprognostic (1.97e-1)" "unprognostic (1.43e-1)" "unprognostic (3.00e-1)" "unprognostic (1.65e-2)" TAF1 "BA2R, CCG1, CCGS, DYT3, DYT3/TAF1, KAT4, NSCL2, TAF2A, TAFII250" ENSG00000147133 "TATA-box binding protein associated factor 1" P21675 X 71366222-71532374 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Acyltransferase, DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Dystonia, Intellectual disability, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "HPA001075, CAB016283" Supported Supported Nucleoplasm NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 6: Non-specific - Immune response" "Cluster 36: Non-specific - mRNA processing" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 45 Nucleoplasm "CAB016283: , HPA001075: " "unprognostic (5.31e-2)" "unprognostic (1.96e-2)" "unprognostic (1.09e-1)" "unprognostic (2.50e-1)" "unprognostic (3.32e-2)" "unprognostic (9.56e-2)" "unprognostic (2.85e-2)" "unprognostic (2.40e-2)" "unprognostic (1.66e-2)" "potential prognostic unfavorable (2.58e-4)" "unprognostic (3.13e-2)" "potential prognostic favorable (3.67e-4)" "unprognostic (1.27e-1)" "unprognostic (6.43e-2)" "unprognostic (1.48e-1)" "unprognostic (1.82e-2)" "unprognostic (1.08e-2)" "unprognostic (3.16e-2)" "unprognostic (5.27e-2)" "unprognostic (3.64e-2)" "unprognostic (1.01e-1)" "unprognostic (1.36e-1)" "unprognostic (2.30e-2)" "unprognostic (4.37e-2)" "unprognostic (1.42e-2)" "unprognostic (1.15e-2)" "unprognostic (4.14e-2)" "unprognostic (1.12e-1)" "unprognostic (4.05e-1)" "unprognostic (9.15e-3)" "unprognostic (1.43e-1)" TAF10 "TAF2A, TAF2H, TAFII30" ENSG00000166337 "TATA-box binding protein associated factor 10" Q12962 11 6606294-6612539 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 156.2;Late spermatids: 302.1;Megakaryocytes: 204.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004148, CAB022405" Supported Supported Nucleoplasm NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 52 Nucleoplasm "CAB022405: , HPA004148: " "unprognostic (6.86e-2)" "unprognostic (6.85e-3)" "unprognostic (3.97e-1)" "unprognostic (1.30e-1)" "unprognostic (2.81e-2)" "unprognostic (3.68e-2)" "unprognostic (2.24e-2)" "unprognostic (1.39e-1)" "unprognostic (7.45e-2)" "unprognostic (1.60e-1)" "validated prognostic unfavorable (1.02e-9)" "validated prognostic unfavorable (3.95e-5)" "unprognostic (1.05e-1)" "potential prognostic unfavorable (4.89e-4)" "unprognostic (1.24e-1)" "unprognostic (5.25e-3)" "unprognostic (1.27e-3)" "unprognostic (9.34e-2)" "unprognostic (1.97e-1)" "unprognostic (2.22e-3)" "unprognostic (2.19e-1)" "unprognostic (1.25e-1)" "unprognostic (5.21e-2)" "unprognostic (7.17e-2)" "unprognostic (1.50e-1)" "unprognostic (1.11e-1)" "unprognostic (4.72e-2)" "unprognostic (5.50e-2)" "unprognostic (1.03e-1)" "unprognostic (2.02e-2)" "unprognostic (2.54e-1)" TAF11 "TAF2I, TAFII28" ENSG00000064995 "TATA-box binding protein associated factor 11" Q15544 6 34877462-34889192 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029326, HPA049127" Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 2: Neurons - Nucleosome" "Cluster 28: Non-specific - Nuclear processes" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 16 Nucleoplasm "Golgi apparatus" "HPA029326: , HPA049127: " "unprognostic (2.43e-1)" "unprognostic (4.32e-2)" "unprognostic (5.51e-2)" "unprognostic (2.43e-1)" "unprognostic (1.14e-2)" "unprognostic (3.04e-2)" "unprognostic (7.05e-3)" "unprognostic (1.70e-2)" "unprognostic (1.85e-1)" "unprognostic (4.79e-2)" "potential prognostic favorable (9.27e-4)" "unprognostic (9.97e-3)" "unprognostic (1.49e-2)" "unprognostic (1.16e-3)" "unprognostic (1.31e-2)" "unprognostic (2.54e-1)" "unprognostic (5.10e-2)" "unprognostic (3.00e-2)" "unprognostic (6.69e-3)" "unprognostic (2.64e-2)" "unprognostic (1.57e-1)" "unprognostic (3.99e-1)" "potential prognostic unfavorable (7.88e-4)" "potential prognostic unfavorable (3.76e-4)" "unprognostic (2.84e-2)" "unprognostic (1.60e-1)" "unprognostic (9.65e-3)" "unprognostic (1.08e-1)" "unprognostic (1.54e-1)" "unprognostic (1.06e-1)" "unprognostic (2.81e-1)" TAF11L10 ENSG00000284356 "TATA-box binding protein associated factor 11 like 10" "A0A1W2PP81, P0DW11, P0DW12, P0DW13, P0DW14" 5 17597232-17597828 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "basal ganglia: 1.6;cerebral cortex: 2.7;hippocampal formation: 1.4;white matter: 1.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 53: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" TAF11L11 ENSG00000283740 "TATA-box binding protein associated factor 11 like 11" A0A1W2PQ09 5 17604177-17605377 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 53: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" TAF11L12 ENSG00000249156 "TATA-box binding protein associated factor 11 like 12" A0A1W2PPW3 5 17610496-17611583 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 27: Breast cancer - Unknown function" TAF11L13 ENSG00000283776 "TATA-box binding protein associated factor 11 like 13" A0A1W2PPH5 5 17632088-17632684 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 27: Breast cancer - Unknown function" TAF11L14 ENSG00000250782 "TATA-box binding protein associated factor 11 like 14" A0A1W2PPL8 5 17634460-17635053 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 27: Breast cancer - Unknown function" TAF11L2 ENSG00000284373 "TATA-box binding protein associated factor 11 like 2" A6NLC8 5 17498231-17498827 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" NA NA TAF11L3 ENSG00000284439 "TATA-box binding protein associated factor 11 like 3" A0A1W2PRV1 5 17518367-17518963 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA TAF11L4 ENSG00000284283 "TATA-box binding protein associated factor 11 like 4" A0A1W2PPE2 5 17521801-17522397 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA TAF11L5 ENSG00000284234 "TATA-box binding protein associated factor 11 like 5" "A0A1W2PP81, P0DW11, P0DW12, P0DW13, P0DW14" 5 17525235-17525831 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "basal ganglia: 1.6;cerebral cortex: 2.7;hippocampal formation: 1.4;white matter: 1.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 53: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" TAF11L6 ENSG00000284042 "TATA-box binding protein associated factor 11 like 6" "A0A1W2PP81, P0DW11, P0DW12, P0DW13, P0DW14" 5 17528669-17529265 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA TAF11L7 ENSG00000284465 "TATA-box binding protein associated factor 11 like 7" "A0A1W2PP81, P0DW11, P0DW12, P0DW13, P0DW14" 5 17585162-17585758 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 50: Lymphoma - Unknown function" TAF11L8 ENSG00000283967 "TATA-box binding protein associated factor 11 like 8" "A0A1W2PP81, P0DW11, P0DW12, P0DW13, P0DW14" 5 17590364-17590960 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA TAF11L9 ENSG00000283988 "TATA-box binding protein associated factor 11 like 9" A0A1W2PR64 5 17593798-17594394 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA TAF12 "TAF2J, TAFII20" ENSG00000120656 "TATA-box binding protein associated factor 12" Q16514 1 28587829-28648291 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 199.0;Early primary spermatocytes: 333.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008519 Approved NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 55: Breast - Lactation" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 55: Lymphoma - Immune response" "Cluster 3: Early primary spermatocytes - Early meiosis" 80 "HPA008519: " "unprognostic (1.98e-3)" "unprognostic (2.80e-1)" "unprognostic (1.45e-3)" "unprognostic (1.88e-1)" "unprognostic (3.49e-1)" "unprognostic (2.71e-3)" "unprognostic (3.09e-2)" "unprognostic (3.28e-1)" "unprognostic (4.12e-2)" "unprognostic (3.63e-1)" "unprognostic (2.44e-3)" "unprognostic (1.66e-2)" "unprognostic (9.82e-3)" "validated prognostic unfavorable (1.14e-4)" "validated prognostic unfavorable (1.79e-4)" "unprognostic (4.59e-2)" "unprognostic (3.63e-2)" "unprognostic (1.21e-1)" "unprognostic (7.24e-2)" "unprognostic (5.58e-2)" "unprognostic (1.21e-1)" "unprognostic (2.85e-3)" "unprognostic (2.18e-1)" "unprognostic (3.49e-1)" "unprognostic (9.70e-2)" "unprognostic (1.50e-1)" "unprognostic (6.70e-3)" "unprognostic (5.79e-2)" "unprognostic (2.45e-1)" "unprognostic (2.64e-1)" "unprognostic (2.33e-1)" TAF13 "TAF2K, TAFII18" ENSG00000197780 "TATA-box binding protein associated factor 13" Q15543 1 109062496-109076012 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 203.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044492 Approved Enhanced Nucleoplasm,Nucleoli NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 13 Nucleoplasm Nucleoli "HPA044492: " "unprognostic (6.60e-2)" "unprognostic (1.86e-2)" "unprognostic (2.53e-1)" "unprognostic (9.45e-2)" "potential prognostic favorable (5.32e-5)" "unprognostic (2.19e-1)" "unprognostic (1.13e-1)" "potential prognostic unfavorable (1.10e-5)" "unprognostic (7.92e-2)" "unprognostic (1.18e-1)" "validated prognostic favorable (4.24e-6)" "validated prognostic favorable (2.98e-4)" "unprognostic (2.44e-1)" "unprognostic (6.03e-3)" "unprognostic (4.06e-2)" "unprognostic (1.69e-2)" "unprognostic (1.28e-1)" "unprognostic (6.74e-2)" "unprognostic (1.50e-1)" "unprognostic (9.78e-2)" "unprognostic (1.17e-1)" "unprognostic (9.60e-2)" "unprognostic (9.93e-3)" "unprognostic (9.94e-2)" "unprognostic (1.09e-1)" "unprognostic (1.31e-2)" "unprognostic (7.93e-2)" "unprognostic (5.37e-3)" "unprognostic (5.32e-1)" "unprognostic (2.31e-3)" "unprognostic (1.26e-1)" TAF15 "hTAFII68, Npl3, RBP56, TAF2N" ENSG00000270647 "TATA-box binding protein associated factor 15" Q92804 17 35809482-35864615 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA-binding, RNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 169.5;Choroid plexus epithelial cells: 331.5;Distal convoluted tubule cells: 175.2;Microglia: 187.5;Oligodendrocytes: 179.3;Papillary tip epithelial cells: 166.1;Podocytes: 375.5;Proximal tubule cells: 167.2;Renal collecting duct intercalated cells: 188.3;Renal collecting duct principal cells: 201.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052059, HPA063647" Supported Enhanced Nucleoplasm NA NA 21000 "Cluster 33: Non-specific - ATP binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 27: Breast cancer - Unknown function" "Cluster 102: Non-specific - Mixed function" 82 Nucleoplasm "HPA052059: , HPA063647: " "unprognostic (5.23e-3)" "unprognostic (1.37e-1)" "unprognostic (2.12e-1)" "unprognostic (1.77e-3)" "unprognostic (1.54e-1)" "unprognostic (1.22e-1)" "unprognostic (2.15e-1)" "unprognostic (6.88e-2)" "unprognostic (4.88e-2)" "unprognostic (6.13e-2)" "unprognostic (3.39e-3)" "unprognostic (2.07e-1)" "unprognostic (3.02e-3)" "potential prognostic unfavorable (4.86e-4)" "unprognostic (7.13e-3)" "unprognostic (4.56e-3)" "unprognostic (1.75e-1)" "unprognostic (6.03e-2)" "unprognostic (1.10e-1)" "unprognostic (3.67e-1)" "unprognostic (1.15e-1)" "unprognostic (6.26e-3)" "unprognostic (2.41e-2)" "unprognostic (2.50e-3)" "unprognostic (2.99e-2)" "unprognostic (3.83e-2)" "unprognostic (2.13e-1)" "unprognostic (6.36e-2)" TAF1A "SL1, TAFI48" ENSG00000143498 "TATA-box binding protein associated factor, RNA polymerase I subunit A" Q15573 1 222557902-222589933 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054334 Approved Approved "Nucleoplasm,Microtubules,Primary cilium,Primary cilium tip,Primary cilium transition zone,Basal body" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 7: Non-specific - Transcription" 27 "Nucleoplasm, Microtubules" "Primary cilium, Primary cilium tip, Primary cilium transition zone, Basal body" "HPA054334: " "unprognostic (4.29e-1)" "unprognostic (8.04e-2)" "unprognostic (1.95e-1)" "unprognostic (3.96e-3)" "unprognostic (5.86e-2)" "unprognostic (5.71e-2)" "unprognostic (1.90e-1)" "unprognostic (7.44e-3)" "unprognostic (6.05e-2)" "unprognostic (1.20e-1)" "unprognostic (1.63e-1)" "unprognostic (1.19e-3)" "unprognostic (4.18e-3)" "unprognostic (1.05e-1)" "unprognostic (2.36e-3)" "unprognostic (6.34e-3)" "unprognostic (4.15e-1)" "unprognostic (2.00e-1)" "unprognostic (3.27e-1)" "unprognostic (4.09e-2)" "unprognostic (7.68e-3)" "unprognostic (2.17e-1)" "unprognostic (1.58e-1)" "unprognostic (4.30e-2)" "unprognostic (2.72e-1)" "unprognostic (5.41e-3)" "unprognostic (9.46e-3)" "unprognostic (1.54e-1)" "unprognostic (2.60e-3)" "unprognostic (4.18e-1)" TAF1B "RAF1B, RAFI63, SL1, TAFI63" ENSG00000115750 "TATA-box binding protein associated factor, RNA polymerase I subunit B" Q53T94 2 9843443-9934416 "Essential proteins, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071254 Supported Nucleoplasm,Nucleoli NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 61: Non-specific - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 34: Ciliated cells - Cilia assembly & function" 36 Nucleoli Nucleoplasm "HPA071254: " "unprognostic (1.35e-2)" "unprognostic (3.00e-2)" "unprognostic (8.80e-2)" "unprognostic (2.63e-2)" "unprognostic (3.49e-2)" "unprognostic (8.46e-2)" "unprognostic (2.60e-1)" "unprognostic (3.69e-3)" "unprognostic (1.50e-1)" "unprognostic (2.41e-3)" "potential prognostic favorable (2.70e-6)" "unprognostic (1.35e-2)" "unprognostic (1.69e-1)" "potential prognostic unfavorable (2.23e-7)" "unprognostic (2.25e-2)" "unprognostic (3.44e-2)" "unprognostic (2.11e-2)" "unprognostic (6.04e-3)" "unprognostic (1.87e-2)" "unprognostic (2.84e-1)" "unprognostic (5.60e-2)" "unprognostic (8.55e-2)" "unprognostic (2.08e-3)" "unprognostic (2.68e-1)" "unprognostic (3.80e-2)" "unprognostic (5.71e-2)" "unprognostic (2.99e-2)" "unprognostic (1.87e-1)" "unprognostic (1.44e-1)" "unprognostic (4.27e-2)" "unprognostic (2.39e-2)" TAF1C "MGC:39976, SL1, TAFI110, TAFI95" ENSG00000103168 "TATA-box binding protein associated factor, RNA polymerase I subunit C" Q15572 16 84177847-84187070 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Tuft cells: 46.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072229 Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 64: Non-specific - Transcription" "Cluster 19: Astrocytes - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 13 "Nucleoplasm, Nucleoli fibrillar center" "HPA072229: " "unprognostic (8.85e-3)" "unprognostic (2.15e-1)" "unprognostic (1.91e-1)" "unprognostic (1.50e-1)" "unprognostic (6.96e-3)" "unprognostic (3.90e-1)" "unprognostic (1.23e-1)" "unprognostic (3.15e-3)" "unprognostic (1.47e-1)" "unprognostic (4.16e-1)" "unprognostic (1.53e-1)" "unprognostic (1.17e-2)" "unprognostic (6.95e-3)" "unprognostic (6.74e-3)" "unprognostic (6.60e-2)" "unprognostic (2.27e-2)" "unprognostic (7.90e-2)" "unprognostic (1.58e-1)" "unprognostic (5.61e-2)" "unprognostic (2.57e-1)" "unprognostic (6.60e-3)" "unprognostic (1.14e-2)" "unprognostic (2.12e-2)" "unprognostic (6.77e-2)" "unprognostic (6.31e-2)" "unprognostic (1.20e-1)" "unprognostic (2.26e-2)" "unprognostic (1.36e-1)" "unprognostic (1.45e-1)" "unprognostic (1.57e-2)" "unprognostic (5.31e-2)" TAF1D "JOSD3, MGC5306, TAF(I)41" ENSG00000166012 "TATA-box binding protein associated factor, RNA polymerase I subunit D" Q9H5J8 11 93729948-93784391 "Essential proteins, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 549.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030703, HPA055935, HPA060385" Uncertain Supported "Nucleoplasm,Nucleoli,Mitotic spindle,Centriolar satellite" Yes No "Cluster 24: Non-specific - Transcription" "Cluster 54: Non-specific - Ribosome" "Cluster 9: Non-specific - Receptor signaling" "Cluster 24: Non-specific - Unknown function" "Cluster 15: Non-specific - Protein processing" 35 Nucleoplasm "Nucleoli, Mitotic spindle, Centriolar satellite" "HPA030703: , HPA055935: , HPA060385: " "unprognostic (6.13e-2)" "unprognostic (2.91e-1)" "unprognostic (2.37e-2)" "unprognostic (3.22e-3)" "unprognostic (5.63e-2)" "unprognostic (2.16e-1)" "unprognostic (2.95e-1)" "potential prognostic favorable (7.79e-4)" "unprognostic (6.61e-2)" "unprognostic (5.43e-2)" "unprognostic (2.87e-3)" "unprognostic (7.66e-2)" "unprognostic (1.97e-2)" "unprognostic (1.79e-2)" "unprognostic (7.26e-3)" "unprognostic (6.19e-2)" "unprognostic (2.30e-3)" "unprognostic (1.61e-1)" "unprognostic (4.18e-1)" "unprognostic (1.88e-1)" "unprognostic (7.25e-2)" "validated prognostic unfavorable (2.73e-4)" "validated prognostic unfavorable (3.98e-4)" "unprognostic (4.66e-2)" "potential prognostic favorable (1.44e-4)" "unprognostic (2.28e-2)" "unprognostic (1.42e-2)" "unprognostic (9.81e-2)" "unprognostic (8.67e-2)" "unprognostic (3.51e-1)" "unprognostic (2.15e-1)" TAF1L ENSG00000122728 "TATA-box binding protein associated factor 1 like" Q8IZX4 9 32629454-32635669 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 16 "retina: 1.5;testis: 1.5" "Cell type enhanced" "Detected in some" "Early primary spermatocytes: 2.7;Early spermatids: 8.6;Late spermatids: 1.2;Podocytes: 1.3;Proximal tubule cells: 1.6;Renal collecting duct intercalated cells: 1.1;Renal connecting tubule cells: 1.2;Retinal bipolar cells: 11.0;Undifferentiated spermatogonia: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" HPA056605 Uncertain NA NA "Cluster 47: Testis - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 3 "HPA056605: " TAF2 "CIF150, TAF2B, TAFII150" ENSG00000064313 "TATA-box binding protein associated factor 2" Q6P1X5 8 119730774-119832863 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 140000 "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 18: Adrenal cortex cells - Steroidogensis" 12 "unprognostic (5.57e-2)" "unprognostic (4.76e-3)" "unprognostic (2.09e-1)" "unprognostic (3.84e-2)" "unprognostic (1.68e-1)" "unprognostic (1.78e-2)" "unprognostic (5.81e-2)" "unprognostic (3.98e-3)" "unprognostic (2.91e-1)" "potential prognostic unfavorable (3.94e-5)" "potential prognostic favorable (1.45e-5)" "unprognostic (1.91e-1)" "unprognostic (3.15e-2)" "unprognostic (9.68e-3)" "unprognostic (1.09e-1)" "unprognostic (2.24e-3)" "unprognostic (4.34e-3)" "unprognostic (6.30e-2)" "unprognostic (1.16e-1)" "unprognostic (2.75e-2)" "unprognostic (2.69e-2)" "unprognostic (1.27e-2)" "potential prognostic unfavorable (9.70e-4)" "unprognostic (6.62e-2)" "unprognostic (7.11e-2)" "unprognostic (2.36e-1)" "unprognostic (1.02e-1)" "unprognostic (4.02e-2)" "unprognostic (1.79e-1)" "unprognostic (2.97e-2)" "unprognostic (2.96e-1)" TAF3 "TAF140, TAFII140" ENSG00000165632 "TATA-box binding protein associated factor 3" Q5VWG9 10 7818497-8016631 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Sertoli cells: 430.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066184 Supported "Nucleoplasm,Nuclear membrane" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 23 "Nucleoplasm, Nuclear membrane" "HPA066184: " "unprognostic (9.61e-2)" "unprognostic (3.88e-2)" "unprognostic (3.71e-1)" "unprognostic (4.32e-2)" "unprognostic (1.24e-1)" "unprognostic (1.42e-1)" "unprognostic (2.86e-2)" "potential prognostic favorable (1.71e-4)" "unprognostic (7.60e-2)" "unprognostic (1.60e-2)" "validated prognostic favorable (2.94e-5)" "validated prognostic favorable (9.86e-4)" "unprognostic (1.15e-1)" "potential prognostic unfavorable (5.93e-6)" "unprognostic (1.14e-2)" "unprognostic (8.77e-2)" "unprognostic (3.00e-2)" "unprognostic (7.23e-2)" "unprognostic (3.14e-1)" "unprognostic (1.22e-1)" "potential prognostic unfavorable (1.46e-4)" "unprognostic (8.22e-2)" "unprognostic (2.88e-3)" "unprognostic (7.62e-2)" "unprognostic (9.14e-2)" "unprognostic (1.10e-2)" "unprognostic (3.32e-1)" "unprognostic (4.13e-1)" "unprognostic (3.09e-1)" "unprognostic (8.48e-2)" "unprognostic (9.88e-2)" TAF4 "TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135" ENSG00000130699 "TATA-box binding protein associated factor 4" O00268 20 61953469-62065881 "Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Proximal tubule cells: 54.5;Renal collecting duct intercalated cells: 56.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008599, CAB031484" Supported Supported "Nucleoplasm,Endoplasmic reticulum,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 102: Non-specific - Mixed function" 37 Nucleoplasm "Endoplasmic reticulum, Cytosol" "CAB031484: , HPA008599: " "unprognostic (4.70e-2)" "unprognostic (1.18e-2)" "unprognostic (2.22e-1)" "unprognostic (3.15e-1)" "unprognostic (1.05e-1)" "unprognostic (8.01e-2)" "unprognostic (3.84e-1)" "unprognostic (1.07e-1)" "unprognostic (3.07e-2)" "unprognostic (6.92e-3)" "potential prognostic favorable (1.98e-5)" "unprognostic (4.78e-2)" "unprognostic (1.24e-1)" "unprognostic (5.12e-3)" "unprognostic (2.80e-2)" "unprognostic (5.62e-2)" "unprognostic (1.14e-1)" "unprognostic (6.67e-2)" "unprognostic (3.40e-3)" "unprognostic (7.33e-2)" "unprognostic (1.10e-1)" "unprognostic (2.13e-1)" "potential prognostic unfavorable (9.57e-5)" "unprognostic (6.19e-2)" "unprognostic (1.05e-2)" "unprognostic (9.02e-3)" "unprognostic (3.48e-1)" "unprognostic (1.50e-1)" "unprognostic (2.77e-1)" "unprognostic (1.37e-1)" "unprognostic (1.22e-1)" TAF4B "TAF2C2, TAFII105" ENSG00000141384 "TATA-box binding protein associated factor 4b" Q92750 18 26226445-26391685 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Oogenesis, Spermatogenesis, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 197.6;Choroid plexus epithelial cells: 215.7;Endometrial ciliated cells: 244.4;Endometrial glandular cells: 266.8;Endometrial luminal cells: 439.6;Erythrocyte progenitors: 205.1" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 177.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Spleen - B-cells (Spleen), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028937 Uncertain Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 6 Nucleoplasm "Nucleoli fibrillar center" "HPA028937: " "unprognostic (5.77e-2)" "unprognostic (4.39e-2)" "unprognostic (7.21e-2)" "unprognostic (1.58e-2)" "unprognostic (3.77e-2)" "unprognostic (5.95e-2)" "potential prognostic favorable (3.81e-5)" "unprognostic (1.46e-2)" "unprognostic (2.10e-1)" "unprognostic (3.15e-1)" "unprognostic (1.65e-2)" "unprognostic (7.40e-2)" "unprognostic (4.67e-1)" "unprognostic (2.02e-1)" "potential prognostic favorable (5.06e-4)" "unprognostic (1.90e-2)" "unprognostic (3.61e-1)" "unprognostic (5.95e-2)" "unprognostic (1.52e-1)" TAF5 "TAF2D, TAFII100" ENSG00000148835 "TATA-box binding protein associated factor 5" Q15542 10 103367966-103389065 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 8.9" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 45.4;Early primary spermatocytes: 71.9;Undifferentiated spermatogonia: 42.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006195, HPA006474" Supported Supported Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 39: Testis - Nuclear processes" "Cluster 35: Non-specific - DNA binding" "Cluster 52: Non-specific - Mitochondria" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 30 Nucleoplasm "HPA006195: , HPA006474: " "unprognostic (3.85e-2)" "unprognostic (8.94e-2)" "unprognostic (2.95e-1)" "unprognostic (2.59e-1)" "unprognostic (1.10e-1)" "unprognostic (2.16e-1)" "unprognostic (1.48e-1)" "potential prognostic favorable (3.87e-4)" "unprognostic (2.24e-1)" "unprognostic (1.23e-2)" "unprognostic (5.55e-2)" "unprognostic (1.80e-2)" "unprognostic (1.34e-2)" "unprognostic (2.79e-2)" "unprognostic (1.22e-2)" "unprognostic (6.25e-2)" "unprognostic (5.78e-2)" "unprognostic (1.32e-2)" "unprognostic (1.86e-1)" "unprognostic (3.04e-1)" "unprognostic (1.24e-1)" "unprognostic (4.51e-3)" "unprognostic (8.45e-2)" "unprognostic (4.23e-2)" "unprognostic (4.15e-1)" "unprognostic (7.12e-3)" "unprognostic (3.73e-3)" "unprognostic (1.64e-1)" "unprognostic (3.17e-1)" "unprognostic (3.08e-2)" TAF5L PAF65B ENSG00000135801 "TATA-box binding protein associated factor 5 like" O75529 1 229593134-229626122 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 73.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067941 Supported "Nuclear speckles,Cytoplasmic bodies" NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 6: Non-specific - Immune response" "Cluster 45: Non-specific - Nuclear processes" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 44 "Nuclear speckles" "Cytoplasmic bodies" "HPA067941: " "unprognostic (6.12e-2)" "unprognostic (1.79e-1)" "unprognostic (2.24e-1)" "unprognostic (2.12e-3)" "unprognostic (1.71e-2)" "unprognostic (1.47e-1)" "unprognostic (3.98e-2)" "potential prognostic favorable (5.00e-4)" "unprognostic (6.23e-2)" "unprognostic (2.26e-2)" "unprognostic (6.88e-3)" "unprognostic (4.78e-1)" "unprognostic (4.79e-2)" "unprognostic (1.65e-1)" "unprognostic (2.70e-1)" "unprognostic (5.84e-2)" "potential prognostic unfavorable (3.53e-6)" "unprognostic (1.58e-1)" "unprognostic (7.36e-2)" "unprognostic (1.52e-1)" "unprognostic (2.30e-2)" "unprognostic (2.88e-2)" "unprognostic (1.77e-1)" "unprognostic (2.18e-2)" "unprognostic (6.76e-3)" "unprognostic (1.60e-1)" "unprognostic (3.47e-1)" "unprognostic (3.45e-1)" "unprognostic (3.03e-1)" "unprognostic (2.83e-2)" "unprognostic (2.24e-1)" TAF6 "MGC:8964, TAF2E, TAFII70, TAFII80, TAFII85" ENSG00000106290 "TATA-box binding protein associated factor 6" P49848 7 100106876-100119841 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 84.5;Late spermatids: 73.1;Migrating cytotrophoblasts: 69.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006566 Supported Nucleoplasm,Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 24: Non-specific - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 42 Nucleoplasm Cytosol "HPA006566: " "unprognostic (2.84e-2)" "unprognostic (6.40e-2)" "unprognostic (2.25e-1)" "unprognostic (5.79e-3)" "unprognostic (8.54e-2)" "unprognostic (1.97e-1)" "unprognostic (9.24e-2)" "unprognostic (2.45e-1)" "unprognostic (3.80e-1)" "unprognostic (2.76e-3)" "unprognostic (1.40e-1)" "unprognostic (3.03e-1)" "unprognostic (6.98e-2)" "potential prognostic unfavorable (1.22e-4)" "unprognostic (3.68e-3)" "unprognostic (1.27e-2)" "unprognostic (8.57e-3)" "unprognostic (3.31e-2)" "unprognostic (2.68e-2)" "unprognostic (8.79e-2)" "unprognostic (1.03e-1)" "unprognostic (3.35e-2)" "unprognostic (9.24e-3)" "unprognostic (5.83e-1)" "unprognostic (8.52e-2)" "unprognostic (1.90e-2)" "unprognostic (3.05e-1)" "unprognostic (2.12e-1)" "unprognostic (4.86e-1)" "unprognostic (8.88e-2)" "unprognostic (2.71e-1)" TAF6L PAF65A ENSG00000162227 "TATA-box binding protein associated factor 6 like" Q9Y6J9 11 62771357-62787342 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067239 Approved Supported Nucleoplasm NA NA "Cluster 18: Non-specific - Translation" "Cluster 24: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 65: Non-specific - Cell growth & division" 65 Nucleoplasm "HPA067239: " "unprognostic (1.58e-1)" "unprognostic (1.31e-1)" "unprognostic (1.55e-1)" "unprognostic (7.95e-2)" "unprognostic (3.15e-1)" "unprognostic (5.47e-2)" "unprognostic (2.42e-1)" "unprognostic (1.45e-2)" "unprognostic (1.07e-2)" "unprognostic (7.52e-2)" "unprognostic (1.61e-1)" "unprognostic (1.33e-1)" "potential prognostic favorable (7.07e-4)" "unprognostic (6.01e-2)" "unprognostic (1.70e-1)" "unprognostic (1.99e-1)" "unprognostic (1.91e-1)" "unprognostic (2.22e-2)" "unprognostic (1.62e-3)" "unprognostic (6.68e-3)" "unprognostic (1.41e-1)" "unprognostic (1.73e-3)" "unprognostic (3.19e-2)" "unprognostic (2.30e-1)" "unprognostic (1.04e-2)" "unprognostic (1.00e-1)" "unprognostic (3.33e-2)" "unprognostic (2.27e-2)" "unprognostic (1.17e-1)" "unprognostic (1.16e-1)" "unprognostic (2.62e-2)" TAF7 "TAF2F, TAFII55" ENSG00000178913 "TATA-box binding protein associated factor 7" Q15545 5 141259884-141320784 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 345.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006429 Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 19 Nucleoplasm "Golgi apparatus" "HPA006429: " "unprognostic (1.55e-1)" "unprognostic (2.18e-3)" "potential prognostic unfavorable (2.11e-4)" "unprognostic (1.49e-1)" "unprognostic (7.58e-2)" "unprognostic (1.64e-2)" "unprognostic (9.62e-2)" "unprognostic (1.55e-1)" "unprognostic (4.19e-3)" "unprognostic (5.15e-2)" "unprognostic (2.01e-3)" "unprognostic (3.60e-2)" "unprognostic (1.32e-1)" "unprognostic (1.16e-1)" "unprognostic (3.33e-2)" "unprognostic (2.74e-2)" "unprognostic (3.86e-1)" "unprognostic (1.30e-1)" "unprognostic (2.93e-1)" "unprognostic (3.55e-1)" "unprognostic (1.15e-1)" "unprognostic (1.21e-1)" "potential prognostic unfavorable (7.91e-4)" "unprognostic (3.48e-2)" "unprognostic (1.62e-3)" "unprognostic (2.35e-2)" "unprognostic (1.16e-1)" "unprognostic (2.24e-2)" "unprognostic (1.50e-1)" "unprognostic (1.14e-2)" "unprognostic (2.73e-1)" TAF7L "CT40, TAF2Q" ENSG00000102387 "TATA-box binding protein associated factor 7 like" Q5H9L4 X 101268253-101293057 "Predicted intracellular proteins" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 29.5" "Cell type enriched" "Detected in some" 5 "Sertoli cells: 256.1" "Cell type enhanced" "Detected in many" "hippocampal dentate gyrus: 50.1" "Cancer enhanced" "Detected in some" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 4.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 4.6;thyroid cancer: 5.1" "Kidney - Intercalated cells, Pituitary gland - Gonadotropes, Testis - Sertoli cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA001879, HPA072008" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 4 Nucleoplasm Cytosol "HPA001879: , HPA072008: " "unprognostic (2.58e-1)" "potential prognostic favorable (7.96e-4)" "unprognostic (4.42e-2)" "unprognostic (3.39e-3)" "unprognostic (7.14e-3)" "unprognostic (4.78e-3)" TAF8 "FLJ32821, TAF(II)43, TBN" ENSG00000137413 "TATA-box binding protein associated factor 8" Q7Z7C8 6 42050513-42087461 "Disease related genes, Essential proteins, Predicted intracellular proteins" "Differentiation, Transcription, Transcription regulation" "Developmental protein" "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial luminal cells: 257.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031730, HPA031731, HPA031734" Supported Enhanced "Nucleoplasm,Mid piece" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 28: Non-specific - Nuclear processes" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 18 Nucleoplasm "Mid piece" "HPA031730: , HPA031731: , HPA031734: " "unprognostic (5.34e-3)" "unprognostic (2.21e-3)" "unprognostic (1.40e-1)" "unprognostic (1.93e-1)" "unprognostic (3.84e-1)" "unprognostic (3.64e-2)" "unprognostic (1.22e-1)" "unprognostic (2.74e-1)" "unprognostic (2.04e-2)" "unprognostic (7.48e-2)" "unprognostic (9.29e-3)" "potential prognostic favorable (8.24e-5)" "unprognostic (3.17e-2)" "unprognostic (4.62e-2)" "unprognostic (2.41e-1)" "unprognostic (8.47e-2)" "unprognostic (1.30e-1)" "unprognostic (1.64e-1)" "unprognostic (8.63e-2)" "unprognostic (9.25e-2)" "unprognostic (6.96e-2)" "unprognostic (5.19e-2)" "unprognostic (3.00e-1)" "unprognostic (2.31e-1)" "unprognostic (2.01e-3)" "unprognostic (2.06e-3)" "unprognostic (3.18e-3)" "unprognostic (2.21e-1)" "unprognostic (2.58e-1)" "unprognostic (2.72e-1)" "unprognostic (1.03e-1)" TAF9 "AD-004, CGI-137, MGC1603, MGC3647, MGC5067, TAF2G, TAFII31, TAFII32, TAFIID32" ENSG00000273841 "TATA-box binding protein associated factor 9" Q16594 5 69362026-69370013 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Early spermatids: 2.7;Epicardial cells: 2.3;Epididymal clear cells: 2.0;Erythrocyte progenitors: 2.7;Late primary spermatocytes: 3.1;Late spermatids: 5.6;Pancreatic acinar cells: 2.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028930, HPA053429, HPA058961, HPA072658" Approved Enhanced Nucleoplasm NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 14: Neurons - Synaptic function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 17: Non-specific - RNA processing" 70 Nucleoplasm "HPA028930: , HPA053429: , HPA058961: , HPA072658: " "unprognostic (7.47e-2)" "unprognostic (3.28e-2)" "unprognostic (1.30e-2)" "unprognostic (7.08e-2)" "unprognostic (2.37e-2)" "unprognostic (2.15e-1)" "unprognostic (1.25e-2)" "unprognostic (2.39e-2)" "potential prognostic unfavorable (2.06e-4)" "potential prognostic favorable (9.21e-6)" "unprognostic (2.02e-1)" "unprognostic (6.90e-2)" "potential prognostic unfavorable (4.01e-4)" "unprognostic (1.78e-3)" "unprognostic (6.36e-2)" "unprognostic (1.03e-1)" "unprognostic (1.65e-1)" "unprognostic (2.68e-1)" "unprognostic (2.86e-1)" "unprognostic (2.09e-1)" "unprognostic (1.43e-1)" "unprognostic (1.44e-2)" "unprognostic (3.19e-1)" "unprognostic (2.44e-1)" "unprognostic (4.10e-1)" "unprognostic (1.49e-1)" "unprognostic (9.40e-2)" "unprognostic (1.36e-1)" TAF9B "DN-7, DN7, TAF9L, TAFII31L, TFIID-31" ENSG00000187325 "TATA-box binding protein associated factor 9b" Q9HBM6 X 78129748-78139650 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 82.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045275, HPA058961" Approved Approved Nucleoplasm NA NA "Cluster 11: T-cells - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 55: Non-specific - Transcription" "Cluster 36: Non-specific - mRNA processing" "Cluster 62: Smooth muscle cells - Muscle contraction" 52 Nucleoplasm "HPA045275: , HPA058961: " "unprognostic (1.33e-1)" "unprognostic (1.28e-3)" "unprognostic (2.91e-3)" "unprognostic (2.36e-3)" "unprognostic (1.35e-1)" "unprognostic (3.84e-2)" "unprognostic (1.51e-2)" "unprognostic (8.52e-2)" "unprognostic (2.32e-1)" "unprognostic (1.47e-3)" "potential prognostic favorable (1.86e-4)" "unprognostic (7.97e-2)" "unprognostic (6.10e-2)" "unprognostic (1.15e-1)" "unprognostic (1.92e-3)" "unprognostic (1.20e-1)" "unprognostic (1.54e-1)" "unprognostic (2.63e-1)" "unprognostic (4.46e-1)" "unprognostic (3.11e-2)" "unprognostic (2.12e-1)" "unprognostic (1.29e-1)" "unprognostic (4.27e-2)" "unprognostic (8.17e-2)" "unprognostic (4.25e-2)" "unprognostic (2.90e-2)" "unprognostic (4.07e-2)" "unprognostic (7.20e-2)" "unprognostic (4.59e-2)" "unprognostic (1.45e-1)" "unprognostic (3.20e-2)" TAFA1 "FAM19A1, TAFA-1" ENSG00000183662 "TAFA chemokine like family member 1" Q7Z5A9 3 68004247-68545621 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 18.3;choroid plexus: 6.8" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 329.7;Astrocytes: 137.2;Brain excitatory neurons: 932.5;Brain inhibitory neurons: 109.1;Oligodendrocyte progenitor cells: 561.1;Other brain neurons: 161.6" "Cell type enhanced" "Detected in all" "lower rhombic lip: 2599.0;mammillary body: 3057.2" "Cancer enhanced" "Detected in single" "Glioblastoma Multiforme (TCGA): 1.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 7.6;MAIT T-cell: 4.8;memory CD4 T-cell: 5.6;memory CD8 T-cell: 4.4;naive CD4 T-cell: 4.1;naive CD8 T-cell: 5.4;T-reg: 2.8" "Lineage enriched" "Detected in many" 8 "T-cells: 7.6" "Not detected" "Not detected" "Adrenal gland - Adrenal medulla cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "amygdala: 19.9;cerebral cortex: 55.9;hippocampal formation: 52.2" HPA013407 Approved "Secreted in brain" "No annotated function" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 73: Brain - Neuronal signaling" "Cluster 24: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 35: Neurons - Synaptic function & neurogenesis" 4 "HPA013407: " "unprognostic (1.12e-1)" "unprognostic (1.03e-2)" "potential prognostic favorable (6.51e-5)" TAFA2 "FAM19A2, TAFA-2" ENSG00000198673 "TAFA chemokine like family member 2" Q8N3H0 12 61708273-62279150 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.4" "Cell type enhanced" "Detected in all" "Brain excitatory neurons: 696.4;Brain inhibitory neurons: 467.6;Early spermatids: 396.3;Epicardial cells: 591.3;Hematopoietic stem cells: 2115.6;Megakaryocyte-Erythroid progenitors: 650.6;Neutrophil progenitors: 752.8;Neutrophils: 755.1;Oligodendrocyte progenitor cells: 691.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Thyroid Carcinoma (TCGA): 4.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 31.7;neutrophil: 12.1" "Lineage enriched" "Detected in many" 8 "granulocytes: 31.7" "Cancer enhanced" "Detected in some" "Bone cancer: 3.7;Leukemia: 5.2" "Colon - Colon enteroendocrine cells, Pituitary gland - Somatotropes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Intracellular and membrane" "No annotated function" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 35: Neurons - Synaptic function & neurogenesis" "unprognostic (4.26e-1)" "unprognostic (1.66e-1)" "potential prognostic favorable (1.25e-4)" "unprognostic (5.64e-2)" "unprognostic (5.11e-2)" "unprognostic (7.89e-2)" "unprognostic (7.71e-2)" "unprognostic (3.21e-2)" "unprognostic (2.50e-1)" TAFA3 "FAM19A3, TAFA-3" ENSG00000184599 "TAFA chemokine like family member 3" Q7Z5A8 1 112718905-112727235 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 12.9;retina: 42.5" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 31.9;Cone photoreceptor cells: 105.6;Early spermatids: 13.2;Late primary spermatocytes: 22.8;Late spermatids: 26.2;Müller glia: 10.9;Myonuclei: 17.6;Retinal bipolar cells: 49.1;Retinal pigment epithelial cells: 29.8;Rod photoreceptor cells: 9.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Rhabdoid: 14.0;skin cancer: 4.5" "Adrenal gland - Adrenal medulla cells, Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in single" 21 "olfactory bulb: 3.5" "Low region specificity" "Detected in all" HPA055927 Approved "Secreted in other tissues" "No annotated function" NA NA "Cluster 42: Retina - Visual perception" "Cluster 38: Sub-cortical - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "HPA055927: " "unprognostic (1.49e-1)" "unprognostic (2.33e-3)" "unprognostic (4.00e-3)" "unprognostic (7.67e-2)" "unprognostic (1.75e-1)" TAFA4 "FAM19A4, TAFA-4" ENSG00000163377 "TAFA chemokine like family member 4" Q96LR4 3 68731766-68953297 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "adrenal gland: 14.1;brain: 6.9;retina: 10.3;stomach 1: 4.6" "Group enriched" "Detected in many" 4 "Cone photoreceptor cells: 511.3;Retinal bipolar cells: 389.3" "Cell type enhanced" "Detected in many" "LAMP5-LHX6 and Chandelier: 125.9;mammillary body: 330.2;thalamic excitatory: 159.9" "Cancer enhanced" "Detected in some" "Prostate Adenocarcinoma (TCGA): 1.1;Testicular Germ Cell Tumor (TCGA): 1.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "testis cancer: 2.3" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in many" 5 "thalamus: 13.5" "Low region specificity" "Detected in many" "Secreted in brain" "No annotated function" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 1 "unprognostic (1.31e-1)" "unprognostic (3.06e-1)" TAFA5 "FAM19A5, TAFA-5" ENSG00000219438 "TAFA chemokine like family member 5" Q7Z5A7 22 48489553-48850912 "Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 77.6" "Cell type enhanced" "Detected in many" "Astrocytes: 195.3;Bergmann glia: 127.0;Brain excitatory neurons: 160.8;Brain inhibitory neurons: 100.2;Choroid plexus epithelial cells: 99.4;Endometrial stromal cells: 142.7;Ependymal cells: 98.1;Müller glia: 105.5;Oligodendrocyte progenitor cells: 144.9;Other brain neurons: 116.5;Retinal amacrine cells: 168.2;Retinal ganglion cells: 154.5;Schwann cells: 143.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 25.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "Bone cancer: 33.2;Neuroblastoma: 20.1" "Skin - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025629 Approved "Secreted in brain" Cytokine NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 1: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 2: Cerebellar granular cells - Neuronal signaling" "CAB025629: " "potential prognostic favorable (1.39e-4)" "unprognostic (4.45e-1)" "unprognostic (5.44e-2)" "unprognostic (4.04e-2)" "unprognostic (2.86e-2)" "unprognostic (1.88e-1)" "unprognostic (4.33e-1)" "unprognostic (8.00e-2)" "unprognostic (8.63e-2)" "unprognostic (1.07e-2)" "unprognostic (2.10e-3)" "unprognostic (1.70e-2)" "unprognostic (3.14e-2)" "unprognostic (1.08e-1)" "unprognostic (2.00e-1)" "unprognostic (8.61e-3)" "unprognostic (7.72e-2)" "unprognostic (7.12e-2)" "unprognostic (1.97e-3)" "unprognostic (2.32e-2)" "unprognostic (4.66e-2)" "unprognostic (1.62e-1)" "unprognostic (1.43e-2)" "unprognostic (8.06e-2)" "unprognostic (1.12e-1)" "unprognostic (3.36e-3)" "unprognostic (7.53e-2)" "unprognostic (1.87e-3)" "unprognostic (1.27e-1)" TAFAZZIN "BTHS, CMD3A, EFE, EFE2, G4.5, TAZ, TAZ1" ENSG00000102125 "Tafazzin, phospholipid-lysophospholipid transacylase" Q16635 X 154411524-154421726 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Acyltransferase, Transferase" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039557 Approved NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 6: Non-specific - Immune response" "Cluster 36: Non-specific - mRNA processing" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 10 "HPA039557: " "unprognostic (1.28e-1)" "unprognostic (2.13e-1)" "unprognostic (4.40e-3)" "unprognostic (1.92e-3)" "unprognostic (1.27e-2)" "unprognostic (4.33e-2)" "unprognostic (1.54e-1)" "unprognostic (1.56e-3)" "unprognostic (3.44e-1)" "unprognostic (8.83e-3)" "potential prognostic unfavorable (1.68e-9)" "unprognostic (6.68e-3)" "unprognostic (9.86e-3)" "unprognostic (4.40e-2)" "unprognostic (7.75e-2)" "unprognostic (2.65e-1)" "unprognostic (8.38e-2)" "unprognostic (2.81e-1)" "unprognostic (3.99e-2)" "unprognostic (3.59e-2)" "unprognostic (2.15e-3)" "unprognostic (4.75e-2)" "unprognostic (1.68e-3)" "unprognostic (2.15e-1)" "unprognostic (3.41e-1)" "unprognostic (1.76e-1)" "unprognostic (7.50e-3)" "unprognostic (9.48e-3)" "unprognostic (1.50e-1)" "unprognostic (3.13e-1)" "unprognostic (1.49e-2)" TAGAP "ARHGAP47, FLJ32631, IDDM21" ENSG00000164691 "T cell activation RhoGTPase activating protein" Q8N103 6 159034468-159045152 "Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 138.6;lymphoid tissue: 44.6" "Cell type enriched" "Detected in many" 5 "Neutrophils: 837.4" "Group enriched" "Detected in many" 16 "central nervous system macrophage: 47.8;leukocyte: 53.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Leukemia: 9.9;lymphoma: 21.3;Myeloma: 7.5" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Prostate - T-cells, Skeletal muscle - Fibroblasts, Testis - Peritubular cells, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "HPA031000, HPA039982" Uncertain Approved Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 15: Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 12 Cytosol "HPA031000: , HPA039982: " "unprognostic (9.72e-2)" "unprognostic (1.80e-2)" "unprognostic (9.51e-2)" "unprognostic (9.55e-2)" "unprognostic (2.00e-1)" "unprognostic (4.64e-3)" "unprognostic (6.56e-2)" "unprognostic (2.93e-2)" "unprognostic (2.91e-3)" "unprognostic (2.00e-1)" "unprognostic (2.56e-2)" "unprognostic (5.14e-2)" "unprognostic (1.93e-1)" "unprognostic (1.65e-2)" "unprognostic (4.65e-3)" "unprognostic (2.86e-2)" "unprognostic (6.43e-2)" "unprognostic (4.96e-1)" "unprognostic (2.31e-1)" "unprognostic (3.69e-1)" "unprognostic (2.89e-2)" "unprognostic (1.87e-1)" "unprognostic (2.75e-1)" "unprognostic (1.08e-1)" "unprognostic (1.54e-2)" "unprognostic (1.20e-1)" "unprognostic (2.08e-2)" "unprognostic (3.97e-2)" "unprognostic (1.06e-1)" "unprognostic (1.35e-2)" TAGLN "DKFZp686P11128, SM22, SMCC, TAGLN1, WS3-10" ENSG00000149591 Transgelin Q01995 11 117199370-117207464 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Muscle protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 13587.8;intestine: 8800.4" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 8847.7;Decidual stromal cells: 7513.9;Hepatic stellate cells: 8894.7;Pericytes: 3505.4;Peritubular myoid cells: 1928.7;Salivary myoepithelial cells: 2502.0;Smooth muscle cells: 13251.0;Vascular smooth muscle cells: 11546.2" "Cell type enriched" "Detected in all" 24 "vascular associated smooth muscle cell: 2667.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "intermediate monocyte: 42.0;non-classical monocyte: 63.9" "Lineage enriched" "Detected in many" 11 "monocytes: 63.9" "Cancer enhanced" "Detected in all" "Bile duct cancer: 653.2;testis cancer: 743.9" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Colon - Smooth muscle cells, Heart muscle - Smooth muscle cells, Kidney - Fibroblasts, Lung - Smooth muscle cells, Pituitary gland - Fibroblasts, Prostate - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001447, HPA019467, HPA061657" Enhanced Approved Nucleoplasm,Microtubules,Mitochondria,Cytosol No No 6000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 6 "Mitochondria, Cytosol" "Nucleoplasm, Microtubules" "CAB001447: , HPA019467: , HPA061657: " "unprognostic (1.40e-2)" "unprognostic (2.67e-2)" "unprognostic (2.72e-2)" "unprognostic (3.93e-2)" "unprognostic (1.12e-2)" "unprognostic (2.99e-2)" "unprognostic (4.00e-2)" "unprognostic (4.95e-3)" "unprognostic (1.34e-2)" "unprognostic (2.94e-1)" "unprognostic (1.12e-1)" "unprognostic (5.05e-3)" "potential prognostic unfavorable (1.83e-5)" "unprognostic (9.91e-3)" "unprognostic (9.88e-2)" "unprognostic (1.73e-1)" "unprognostic (1.72e-2)" "unprognostic (6.96e-3)" "unprognostic (1.68e-2)" "unprognostic (1.15e-1)" "unprognostic (1.45e-3)" "unprognostic (2.83e-2)" "unprognostic (2.96e-2)" "unprognostic (5.14e-2)" "unprognostic (1.03e-2)" "unprognostic (1.44e-2)" "unprognostic (2.45e-2)" "unprognostic (1.90e-2)" "unprognostic (2.68e-1)" "unprognostic (9.19e-2)" "unprognostic (9.94e-2)" TAGLN2 "HA1756, KIAA0120" ENSG00000158710 "Transgelin 2" P37802 1 159918107-159925507 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 3047.5;Megakaryocytes: 2330.5;Platelets: 5153.5" "Cell type enhanced" "Detected in many" "endothelial cell: 138.6;pericyte: 102.0;vascular associated smooth muscle cell: 86.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pituitary gland - Endothelial cells, Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA001925 Approved Approved "Vesicles,Actin filaments,Basal body,Cytosol" NA NA 300000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 47: Platelets - Hemostasis" 25 Cytosol "Vesicles, Actin filaments, Basal body" "HPA001925: " "potential prognostic unfavorable (1.24e-4)" "potential prognostic unfavorable (8.62e-6)" "unprognostic (5.88e-2)" "unprognostic (1.23e-1)" "unprognostic (3.66e-3)" "unprognostic (2.95e-1)" "unprognostic (2.88e-2)" "potential prognostic unfavorable (3.12e-6)" "unprognostic (1.79e-1)" "unprognostic (4.64e-2)" "potential prognostic unfavorable (5.80e-5)" "unprognostic (1.17e-2)" "unprognostic (6.13e-2)" "potential prognostic unfavorable (2.22e-5)" "unprognostic (1.26e-1)" "unprognostic (3.31e-2)" "unprognostic (9.42e-3)" "unprognostic (2.02e-1)" "potential prognostic unfavorable (7.92e-5)" "unprognostic (1.56e-1)" "unprognostic (2.14e-1)" "unprognostic (3.31e-3)" "unprognostic (2.52e-1)" "unprognostic (2.53e-1)" "unprognostic (3.79e-2)" "unprognostic (8.06e-2)" "unprognostic (1.54e-1)" "unprognostic (2.53e-1)" "unprognostic (1.43e-1)" "unprognostic (7.61e-2)" "unprognostic (2.63e-1)" TAGLN3 "NP22, NP25" ENSG00000144834 "Transgelin 3" Q9UI15 3 111998739-112013887 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 474.6" "Cell type enhanced" "Detected in some" "Bergmann glia: 94.2;Brain excitatory neurons: 90.3;Brain inhibitory neurons: 79.7;Corticotrophs: 75.0;Lactotrophs: 36.4;Oligodendrocyte progenitor cells: 42.4;Other brain neurons: 95.0;Pancreatic islet cells: 34.2;Retinal amacrine cells: 100.8;Retinal bipolar cells: 55.1;Retinal ganglion cells: 30.9;Retinal horizontal cells: 166.3;Thyrotrophs: 38.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 64.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "lung cancer: 31.2;Neuroblastoma: 58.4" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Pancreas - Beta cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062620 Enhanced NA NA 11000000 "Cluster 10: Brain - Synaptic signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 98: Neurons - Neurotransmission & signaling" 5 "HPA062620: " "unprognostic (3.63e-3)" "unprognostic (5.85e-2)" "unprognostic (4.61e-1)" "unprognostic (1.01e-3)" "unprognostic (2.82e-1)" "unprognostic (4.38e-2)" "unprognostic (1.57e-1)" "unprognostic (1.73e-2)" "unprognostic (2.84e-1)" "unprognostic (6.24e-2)" "unprognostic (6.79e-3)" "unprognostic (1.53e-1)" "unprognostic (1.74e-1)" "potential prognostic unfavorable (5.19e-5)" TAL1 "bHLHa17, SCL, TCL5" ENSG00000162367 "TAL bHLH transcription factor 1, erythroid differentiation factor" P17542 1 47216290-47232225 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 28.0" "Cell type enhanced" "Detected in some" "Erythrocyte progenitors: 87.4;Erythrocytes: 54.2;Hematopoietic stem cells: 41.7;Hofbauer cells: 36.6;Lymphatic endothelial cells: 53.5;Mast cells: 42.9;Megakaryocyte progenitors: 70.5;Megakaryocyte-Erythroid progenitors: 71.1;Megakaryocytes: 142.2;Microglia: 159.2;Platelets: 523.7" "Cell type enriched" "Detected in some" 5 "central nervous system macrophage: 184.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 10 "Leukemia: 30.0" "Colon - Endothelial cells, Liver - Vascular endothelial cells, Lung - Endothelial cells, Minor Salivary Gland - Endothelial cells, Pituitary gland - Endothelial cells, Prostate - Endothelial cells, Stomach - Endothelial cells" "Region enriched" "Detected in many" 5 "midbrain: 14.3" "Low region specificity" "Detected in many" "CAB017805, HPA047866, HPA073983" Approved Enhanced Nucleoplasm Yes NA "Cluster 15: Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 47: Platelets - Hemostasis" 33 Nucleoplasm "CAB017805: , HPA047866: , HPA073983: " "unprognostic (7.58e-2)" "unprognostic (1.08e-1)" "unprognostic (3.00e-1)" "unprognostic (4.80e-2)" "validated prognostic favorable (2.76e-6)" "validated prognostic favorable (5.94e-4)" "potential prognostic favorable (1.80e-4)" "unprognostic (3.20e-2)" "unprognostic (2.82e-1)" "unprognostic (1.68e-2)" "unprognostic (1.54e-1)" TAL2 bHLHa19 ENSG00000186051 "TAL bHLH transcription factor 2" Q16559 9 105662457-105663124 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "skeletal muscle: 12.8" "Cell type enhanced" "Detected in some" "B-cells: 2.0;Differentiating spermatogonia: 1.2;Distal convoluted tubule cells: 1.2;Müller glia: 3.2;Myonuclei: 2.8;Other brain neurons: 1.3;Somatotrophs: 1.0" "Cell type enhanced" "Detected in single" "oligodendrocyte precursor cell: 1.1" "Cancer enriched" "Detected in some" 4 "Kidney Renal Clear Cell Carcinoma (TCGA): 4.8" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "memory B-cell: 6.9;naive B-cell: 7.3" "Lineage enriched" "Detected in many" 4 "B-cells: 7.3" "Cancer enriched" "Detected in some" 27 "Rhabdoid: 37.0" "Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" HPA030886 Uncertain Approved Cytosol NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 36: Choroid plexus - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 6 Cytosol "HPA030886: " "unprognostic (1.95e-1)" "unprognostic (3.40e-2)" "potential prognostic favorable (2.41e-11)" "unprognostic (1.12e-3)" "unprognostic (2.31e-1)" TALDO1 ENSG00000177156 "Transaldolase 1" P37837 11 747415-765012 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Pentose shunt" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 2295.8;Esophageal suprabasal cells: 1012.9;Megakaryocytes: 1013.8;Neutrophils: 1218.3;Platelets: 1605.8" "Cell type enhanced" "Detected in all" "oligodendrocyte: 131.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 2876.7;neutrophil: 3741.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Macrophages, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040373 Approved Cytosol NA NA 34000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 7: Liver cancer - Metabolism" "Cluster 47: Platelets - Hemostasis" 13 Cytosol "HPA040373: " "unprognostic (6.53e-3)" "unprognostic (3.41e-2)" "unprognostic (1.02e-1)" "unprognostic (2.28e-1)" "unprognostic (3.56e-2)" "unprognostic (1.52e-1)" "unprognostic (1.09e-2)" "unprognostic (1.98e-2)" "unprognostic (9.07e-3)" "unprognostic (3.54e-2)" "unprognostic (2.63e-2)" "unprognostic (2.88e-3)" "potential prognostic unfavorable (2.39e-4)" "potential prognostic unfavorable (3.16e-5)" "unprognostic (6.13e-3)" "unprognostic (1.48e-2)" "unprognostic (1.92e-1)" "unprognostic (3.45e-1)" "unprognostic (4.30e-2)" "unprognostic (3.64e-1)" "unprognostic (3.60e-2)" "unprognostic (2.73e-3)" "unprognostic (2.23e-1)" "unprognostic (1.92e-1)" "unprognostic (2.28e-2)" "unprognostic (1.56e-1)" "unprognostic (1.00e-1)" "unprognostic (2.11e-1)" "unprognostic (9.29e-2)" "unprognostic (1.62e-1)" "unprognostic (1.82e-2)" TAMALIN GRASP ENSG00000161835 "Trafficking regulator and scaffold protein tamalin" Q7Z6J2 12 52006946-52015889 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "B-cells: 84.9;cDC: 162.6;Hematopoietic stem cells: 63.6;Innate lymphoid cells: 116.1;Lymphatic endothelial cells: 64.0;Macrophages: 88.6;Mast cells: 96.6;monocytes: 121.5;NK-cells: 71.3;pDCs: 141.2;Thymocytes: 96.6;Tuft cells: 472.7;Vascular endothelial cells: 162.6" "Cell type enhanced" "Detected in many" "endothelial cell: 130.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 18.1" "Breast - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040664, HPA062028" Approved Approved "Nuclear bodies,Vesicles" No NA "Cluster 74: Non-specific - Signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 82: Dendritic cells - Antigen presentation" 2 Vesicles "Nuclear bodies" "HPA040664: , HPA062028: " "unprognostic (3.48e-1)" "unprognostic (2.76e-1)" "unprognostic (1.70e-1)" "unprognostic (5.37e-2)" "unprognostic (1.69e-3)" "unprognostic (1.51e-1)" "unprognostic (2.78e-1)" "unprognostic (3.02e-2)" "unprognostic (9.10e-2)" "potential prognostic favorable (9.93e-6)" "unprognostic (1.69e-3)" "unprognostic (3.30e-3)" "unprognostic (4.31e-2)" "unprognostic (2.08e-1)" "unprognostic (9.75e-2)" "unprognostic (8.62e-3)" "unprognostic (1.69e-1)" "unprognostic (1.71e-1)" "unprognostic (1.31e-1)" "unprognostic (1.64e-3)" "unprognostic (8.10e-2)" "unprognostic (5.54e-2)" "unprognostic (1.54e-1)" "potential prognostic favorable (3.11e-4)" "unprognostic (8.39e-2)" "unprognostic (5.54e-3)" "unprognostic (3.23e-1)" "unprognostic (3.16e-2)" "unprognostic (1.98e-1)" TAMM41 "C3orf31, DKFZp434E0519, MGC16471" ENSG00000144559 "TAM41 mitochondrial translocator assembly and maintenance homolog" Q96BW9 3 11790442-11846919 "Enzymes, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Nucleotidyltransferase, Transferase" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036834, HPA044861" Uncertain Approved Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 54: Non-specific - Ribosome" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 102: Non-specific - Mixed function" Cytosol "HPA036834: , HPA044861: " "unprognostic (6.98e-3)" "unprognostic (1.58e-2)" "unprognostic (1.36e-2)" "unprognostic (5.89e-2)" "unprognostic (8.19e-3)" "unprognostic (1.46e-1)" "unprognostic (4.60e-2)" "unprognostic (6.95e-2)" "unprognostic (4.72e-2)" "unprognostic (1.52e-1)" "unprognostic (1.43e-1)" "unprognostic (1.90e-1)" "potential prognostic unfavorable (4.99e-4)" "potential prognostic unfavorable (2.97e-4)" "unprognostic (2.07e-3)" "unprognostic (5.66e-2)" "unprognostic (2.72e-1)" "unprognostic (3.36e-1)" "unprognostic (8.35e-2)" "unprognostic (1.31e-3)" "unprognostic (4.76e-3)" "unprognostic (3.04e-1)" "unprognostic (1.62e-2)" "unprognostic (3.75e-1)" "unprognostic (2.52e-1)" "unprognostic (4.68e-1)" "unprognostic (2.98e-1)" "unprognostic (3.99e-1)" "unprognostic (2.19e-1)" TANC1 "KIAA1728, ROLSB" ENSG00000115183 "Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1" Q9C0D5 2 158968640-159232659 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 557.4;Podocytes: 807.6;Retinal ganglion cells: 857.5;Retinal horizontal cells: 855.4" "Cell type enhanced" "Detected in all" "endothelial cell: 690.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036750 Approved NA NA "Cluster 58: Skin - Keratinization" "Cluster 6: Non-specific - Immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 15 "HPA036750: " "unprognostic (6.54e-2)" "unprognostic (8.12e-2)" "unprognostic (3.33e-1)" "unprognostic (1.62e-2)" "unprognostic (1.35e-1)" "unprognostic (2.58e-3)" "unprognostic (1.16e-2)" "unprognostic (7.63e-2)" "unprognostic (1.30e-1)" "unprognostic (1.11e-1)" "validated prognostic favorable (5.39e-8)" "validated prognostic favorable (6.92e-4)" "unprognostic (2.08e-1)" "unprognostic (2.42e-1)" "unprognostic (1.51e-1)" "unprognostic (9.46e-3)" "unprognostic (4.46e-2)" "unprognostic (4.07e-2)" "unprognostic (2.14e-3)" "unprognostic (3.45e-3)" "unprognostic (1.10e-1)" "validated prognostic unfavorable (8.80e-4)" "validated prognostic unfavorable (7.48e-4)" "unprognostic (3.75e-1)" "unprognostic (1.28e-1)" "unprognostic (1.12e-3)" "unprognostic (7.36e-2)" "unprognostic (7.74e-2)" "unprognostic (2.62e-1)" "unprognostic (3.34e-2)" "unprognostic (7.73e-2)" TANC2 "DKFZP564D166, FLJ10215, FLJ11824, KIAA1148, KIAA1636, rols, ROLSA" ENSG00000170921 "Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2" Q9HCD6 17 62966235-63427703 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Autism spectrum disorder, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 26.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 1156.2;Oligodendrocyte progenitor cells: 846.5;Sertoli cells: 1433.0;Somatotrophs: 994.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal medulla cells, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023274 Uncertain Uncertain Cytosol NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 73: Brain - Neuronal signaling" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" 9 Cytosol "HPA023274: " "unprognostic (1.43e-2)" "unprognostic (7.74e-2)" "unprognostic (8.87e-2)" "potential prognostic unfavorable (6.14e-4)" "unprognostic (2.30e-2)" "unprognostic (1.66e-1)" "unprognostic (3.24e-1)" "unprognostic (2.73e-1)" "unprognostic (9.26e-2)" "unprognostic (8.21e-3)" "unprognostic (1.16e-1)" "unprognostic (4.46e-2)" "unprognostic (2.79e-1)" "unprognostic (9.55e-2)" "unprognostic (1.81e-1)" "potential prognostic unfavorable (7.89e-5)" "unprognostic (5.32e-2)" "unprognostic (2.18e-1)" "unprognostic (1.74e-2)" "unprognostic (1.61e-2)" "unprognostic (1.33e-1)" "unprognostic (1.07e-3)" "unprognostic (7.44e-2)" "unprognostic (5.70e-2)" "unprognostic (3.66e-2)" "unprognostic (4.01e-1)" "unprognostic (6.60e-2)" "unprognostic (1.39e-1)" "unprognostic (2.17e-1)" "unprognostic (1.35e-2)" TANGO2 "C22orf25, DKFZp761P1121" ENSG00000183597 "Transport and golgi organization 2 homolog" Q6ICL3 22 20017014-20067164 "Disease related genes, Predicted intracellular proteins" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 73.8" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 151.3;Hofbauer cells: 102.6;Platelets: 121.0;Retinal ganglion cells: 123.6" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 115.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003080 Approved NA NA 220000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 35: Non-specific - Mixed function" "Cluster 45: Non-specific - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 1 "HPA003080: " "unprognostic (7.76e-2)" "unprognostic (4.91e-2)" "unprognostic (3.38e-2)" "unprognostic (3.52e-2)" "unprognostic (1.55e-2)" "unprognostic (1.12e-1)" "unprognostic (1.66e-1)" "unprognostic (2.26e-2)" "unprognostic (1.76e-1)" "unprognostic (1.28e-2)" "unprognostic (8.29e-3)" "potential prognostic favorable (3.21e-7)" "unprognostic (2.40e-2)" "unprognostic (1.06e-2)" "unprognostic (7.39e-2)" "unprognostic (3.48e-1)" "unprognostic (1.34e-1)" "unprognostic (5.13e-2)" "unprognostic (2.17e-1)" "unprognostic (1.21e-2)" "unprognostic (3.22e-2)" "unprognostic (2.20e-1)" "unprognostic (1.79e-1)" "unprognostic (2.05e-1)" "unprognostic (1.39e-1)" "unprognostic (1.64e-1)" "unprognostic (4.83e-2)" "unprognostic (1.37e-1)" "unprognostic (1.64e-2)" TANGO6 "FLJ12688, KIAA1746, TMCO7" ENSG00000103047 "Transport and golgi organization 6 homolog" Q9C0B7 16 68843531-69085182 "Essential proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 221.3;Sertoli cells: 218.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041312 Approved Approved "Golgi apparatus,Cytosol" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Transcription" 34 "Golgi apparatus" Cytosol "HPA041312: " "unprognostic (1.66e-1)" "unprognostic (3.95e-2)" "unprognostic (2.20e-1)" "unprognostic (4.14e-2)" "unprognostic (4.63e-2)" "unprognostic (1.66e-1)" "potential prognostic favorable (1.92e-4)" "unprognostic (9.03e-2)" "unprognostic (7.81e-2)" "potential prognostic favorable (3.59e-7)" "unprognostic (1.80e-3)" "unprognostic (2.83e-1)" "unprognostic (4.48e-1)" "unprognostic (2.28e-1)" "unprognostic (4.89e-2)" "unprognostic (7.59e-2)" "unprognostic (3.50e-1)" "unprognostic (4.15e-2)" "unprognostic (5.22e-3)" "unprognostic (2.27e-1)" "potential prognostic unfavorable (5.56e-6)" "unprognostic (1.11e-1)" "unprognostic (9.50e-2)" "unprognostic (4.09e-3)" "unprognostic (1.50e-1)" "unprognostic (2.12e-2)" "unprognostic (2.10e-1)" "unprognostic (2.22e-2)" "unprognostic (6.37e-2)" TANK "I-TRAF, TRAF2" ENSG00000136560 "TRAF family member associated NFKB activator" Q92844 2 161136908-161236230 "Predicted intracellular proteins" "DNA damage, Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 740.5;Neutrophils: 1955.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast myoepithelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010345, HPA037675, HPA037676" Approved Supported Nucleoli,Cytosol NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 45 Cytosol Nucleoli "CAB010345: , HPA037675: , HPA037676: " "unprognostic (1.69e-2)" "unprognostic (7.48e-2)" "unprognostic (2.44e-2)" "unprognostic (1.74e-1)" "unprognostic (4.34e-1)" "unprognostic (1.83e-1)" "unprognostic (6.25e-2)" "unprognostic (3.07e-2)" "unprognostic (2.76e-2)" "unprognostic (6.60e-2)" "unprognostic (5.32e-3)" "unprognostic (4.12e-2)" "potential prognostic unfavorable (5.97e-4)" "unprognostic (5.56e-3)" "unprognostic (4.47e-2)" "unprognostic (4.61e-2)" "unprognostic (2.74e-1)" "unprognostic (5.25e-2)" "unprognostic (2.10e-2)" "unprognostic (5.58e-2)" "unprognostic (2.97e-1)" "unprognostic (2.14e-2)" "unprognostic (6.56e-3)" "unprognostic (4.29e-2)" "unprognostic (5.00e-1)" "unprognostic (6.61e-2)" "unprognostic (8.04e-2)" "unprognostic (5.69e-3)" "unprognostic (2.17e-1)" "unprognostic (1.54e-2)" "unprognostic (1.99e-1)" TAOK1 "FLJ14314, hKFC-B, hTAOK1, KIAA1361, MAP3K16, MARKK, PSK2, TAO1" ENSG00000160551 "TAO kinase 1" Q7L7X3 17 29390363-29551903 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, DNA damage, DNA repair" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007669, HPA008048, HPA073484" Approved Approved "Vesicles,Plasma membrane,Primary cilium,Cytosol" NA NA 750000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 8 "Plasma membrane, Cytosol" "Vesicles, Primary cilium" "HPA007669: , HPA008048: , HPA073484: " "unprognostic (1.00e-1)" "unprognostic (5.79e-2)" "unprognostic (7.19e-2)" "unprognostic (1.72e-2)" "unprognostic (2.24e-1)" "unprognostic (3.54e-2)" "unprognostic (1.80e-2)" "unprognostic (2.40e-1)" "unprognostic (2.74e-1)" "potential prognostic unfavorable (6.23e-4)" "potential prognostic favorable (2.20e-4)" "unprognostic (1.32e-2)" "unprognostic (2.44e-1)" "unprognostic (6.68e-3)" "unprognostic (3.32e-2)" "unprognostic (1.45e-1)" "unprognostic (7.74e-2)" "unprognostic (2.20e-2)" "unprognostic (6.41e-2)" "unprognostic (1.46e-2)" "unprognostic (1.10e-2)" "unprognostic (5.36e-2)" "unprognostic (1.44e-3)" "unprognostic (2.22e-2)" "unprognostic (1.39e-2)" "unprognostic (7.17e-3)" "unprognostic (1.16e-1)" "unprognostic (6.38e-3)" "unprognostic (3.06e-1)" "unprognostic (4.84e-2)" "unprognostic (7.39e-2)" TAOK2 "hKFC-C, KIAA0881, MAP3K17, PSK, PSK-1, PSK1, PSK1-BETA, TAO1, TAO2, Tao2beta" ENSG00000149930 "TAO kinase 2" Q9UL54 16 29973868-29992261 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Prostate - Endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010650 Approved Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 5: Spleen - Immune response" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 14 "Nucleoplasm, Cytosol" Nucleoli "HPA010650: " "unprognostic (1.95e-2)" "unprognostic (3.11e-2)" "unprognostic (3.82e-1)" "unprognostic (7.38e-2)" "unprognostic (2.75e-2)" "unprognostic (1.73e-2)" "unprognostic (2.55e-1)" "potential prognostic favorable (2.29e-6)" "unprognostic (1.23e-2)" "unprognostic (8.84e-2)" "potential prognostic favorable (2.77e-5)" "unprognostic (3.08e-3)" "unprognostic (1.12e-3)" "unprognostic (1.90e-2)" "unprognostic (1.47e-1)" "unprognostic (1.81e-3)" "unprognostic (1.99e-1)" "unprognostic (1.28e-1)" "unprognostic (1.07e-1)" "unprognostic (1.19e-1)" "unprognostic (1.05e-1)" "unprognostic (8.89e-3)" "unprognostic (2.44e-2)" "unprognostic (2.59e-3)" "unprognostic (9.12e-2)" "unprognostic (1.63e-1)" "unprognostic (1.92e-1)" "unprognostic (9.11e-2)" "unprognostic (3.49e-1)" "unprognostic (1.21e-1)" "unprognostic (1.08e-1)" TAOK3 "DPK, JIK, MAP3K18" ENSG00000135090 "TAO kinase 3" Q9H2K8 12 118149801-118372907 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hematopoietic stem cells: 1069.4;monocytes: 1082.2;Neutrophil progenitors: 998.5;Neutrophils: 1447.5;Rod photoreceptor cells: 1060.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017160 Approved Uncertain Mitochondria NA NA 260000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 55: Non-specific - Transcription" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 6 Mitochondria "HPA017160: " "unprognostic (1.24e-1)" "unprognostic (1.18e-1)" "unprognostic (7.90e-2)" "unprognostic (5.72e-3)" "unprognostic (2.13e-1)" "unprognostic (1.26e-2)" "unprognostic (3.71e-2)" "potential prognostic favorable (6.66e-4)" "unprognostic (1.60e-1)" "potential prognostic unfavorable (9.16e-4)" "potential prognostic favorable (1.35e-5)" "unprognostic (1.81e-2)" "unprognostic (1.59e-1)" "unprognostic (2.04e-1)" "unprognostic (2.74e-1)" "unprognostic (1.20e-1)" "unprognostic (2.34e-1)" "unprognostic (2.32e-2)" "unprognostic (3.96e-2)" "unprognostic (1.12e-1)" "unprognostic (5.19e-3)" "unprognostic (2.97e-2)" "unprognostic (1.24e-1)" "unprognostic (3.53e-2)" "unprognostic (5.39e-2)" "unprognostic (3.99e-1)" "unprognostic (1.08e-1)" "unprognostic (2.26e-1)" "unprognostic (4.42e-1)" "unprognostic (6.72e-2)" "unprognostic (1.25e-2)" TAP1 "ABCB2, D6S114E, PSF1, RING4" ENSG00000168394 "Transporter 1, ATP binding cassette subfamily B member" Q03518 6 32845209-32853816 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Adaptive immunity, Host-virus interaction, Immunity, Peptide transport, Protein transport, Transport" Translocase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 10.8;Bergmann glia: 8.3;Ependymal cells: 5.2;Loop of henle epithelial cells: 6.1;Microglia: 7.7;NK-cells: 8.4;Oligodendrocyte progenitor cells: 12.3;Papillary tip epithelial cells: 9.8;Podocytes: 15.7;Renal collecting duct intercalated cells: 6.7;Renal collecting duct principal cells: 7.0;T-cells: 5.5" "Cell type enhanced" "Detected in many" "endothelial cell: 47.8;leukocyte: 57.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells, Skin - Keratinocyte (other), Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009516, HPA072354" Approved Approved "Endoplasmic reticulum,Centriolar satellite" NA NA 6800 "Cluster 42: Non-specific - Vesicular transport" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 102: Non-specific - Mixed function" 55 "Endoplasmic reticulum, Centriolar satellite" "CAB009516: , HPA072354: " "unprognostic (1.00e-1)" "unprognostic (2.73e-2)" "unprognostic (4.23e-1)" "unprognostic (4.28e-2)" "unprognostic (3.99e-2)" "unprognostic (1.15e-1)" "unprognostic (2.69e-1)" "unprognostic (2.00e-1)" "unprognostic (6.79e-3)" "unprognostic (1.73e-2)" "unprognostic (8.57e-2)" "unprognostic (1.91e-1)" "unprognostic (1.44e-1)" "unprognostic (1.09e-2)" "unprognostic (1.76e-1)" "unprognostic (6.00e-3)" "unprognostic (1.00e-1)" "unprognostic (1.56e-1)" "unprognostic (1.94e-1)" "unprognostic (5.37e-3)" "unprognostic (6.50e-3)" "unprognostic (3.42e-2)" "unprognostic (2.10e-2)" "unprognostic (1.90e-1)" "unprognostic (7.85e-2)" "unprognostic (3.87e-3)" "unprognostic (5.53e-2)" "unprognostic (1.07e-2)" "unprognostic (6.28e-2)" "unprognostic (1.46e-2)" "unprognostic (5.60e-1)" TAP2 "ABCB3, D6S217E, PSF2, RING11" ENSG00000204267 "Transporter 2, ATP binding cassette subfamily B member" Q03519 6 32821833-32838739 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Adaptive immunity, Host-virus interaction, Immunity, Peptide transport, Protein transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 12.5;Bergmann glia: 9.6;Brain excitatory neurons: 7.8;Brain inhibitory neurons: 10.3;Ependymal cells: 5.2;Microglia: 18.7;NK-cells: 3.6;Oligodendrocyte progenitor cells: 14.0;Oligodendrocytes: 5.0;Other brain neurons: 8.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Skeletal muscle - Endothelial cells, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001312 Approved Supported "Nuclear speckles,Endoplasmic reticulum" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 22: Non-specific - Basic cellular functions" 13 "Endoplasmic reticulum" "Nuclear speckles" "HPA001312: " "unprognostic (6.66e-3)" "unprognostic (7.07e-2)" "unprognostic (1.34e-1)" "unprognostic (7.53e-2)" "unprognostic (2.41e-2)" "unprognostic (1.53e-1)" "unprognostic (1.35e-1)" "unprognostic (1.85e-1)" "unprognostic (6.43e-2)" "unprognostic (1.88e-1)" "unprognostic (3.78e-2)" "unprognostic (3.39e-1)" "unprognostic (7.63e-2)" "unprognostic (1.14e-1)" "unprognostic (1.49e-1)" "unprognostic (7.25e-2)" "unprognostic (3.57e-1)" "unprognostic (2.10e-1)" "unprognostic (9.38e-2)" "unprognostic (1.53e-1)" "unprognostic (3.32e-3)" "unprognostic (3.60e-2)" "unprognostic (2.32e-2)" "unprognostic (1.47e-1)" "unprognostic (2.62e-3)" "unprognostic (1.72e-1)" "unprognostic (3.12e-1)" "unprognostic (8.26e-2)" "unprognostic (3.39e-1)" "unprognostic (1.09e-1)" "unprognostic (1.45e-1)" TAPBP TAPA ENSG00000231925 "TAP binding protein" O15533 6 33299694-33314284 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 40.1;Choroid plexus epithelial cells: 58.4;Ependymal cells: 50.6;Loop of henle epithelial cells: 42.1;Microglia: 52.4;Oligodendrocyte progenitor cells: 43.6;Papillary tip epithelial cells: 87.0;Podocytes: 95.5;Proximal tubule cells: 39.9;Renal collecting duct intercalated cells: 41.7;Renal collecting duct principal cells: 56.3" "Cell type enhanced" "Detected in all" "leukocyte: 182.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007066, CAB080405" Approved Approved "Nucleoli,Plasma membrane,Mitochondria" NA NA 8100 "Cluster 32: Basophils - Transcription" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 102: Non-specific - Mixed function" 6 "Nucleoli, Plasma membrane" Mitochondria "CAB080405: , HPA007066: " "unprognostic (1.35e-2)" "unprognostic (1.06e-1)" "unprognostic (4.37e-2)" "unprognostic (5.58e-2)" "unprognostic (5.20e-2)" "unprognostic (1.96e-1)" "unprognostic (3.20e-1)" "unprognostic (1.44e-2)" "unprognostic (9.79e-2)" "unprognostic (1.95e-1)" "unprognostic (5.04e-2)" "unprognostic (4.05e-1)" "unprognostic (3.16e-2)" "unprognostic (3.26e-2)" "unprognostic (1.65e-2)" "unprognostic (1.26e-2)" "unprognostic (2.46e-2)" "unprognostic (3.53e-3)" "unprognostic (4.86e-2)" "unprognostic (1.54e-1)" "unprognostic (1.80e-2)" "unprognostic (2.75e-1)" "unprognostic (2.52e-1)" "unprognostic (3.60e-2)" "unprognostic (1.42e-1)" "unprognostic (2.92e-1)" "potential prognostic favorable (2.18e-4)" "unprognostic (1.85e-1)" "unprognostic (7.80e-2)" "unprognostic (1.28e-1)" "unprognostic (1.78e-1)" TAPBPL "FLJ10143, TAPBP-R, TAPBPR" ENSG00000139192 "TAP binding protein like" Q9BX59 12 6451690-6466517 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Immunity "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 69.8;Enterocytes: 82.1;Epididymal principal cells: 64.8;Plasma cells: 64.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039545 Uncertain NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 8: Immune cells - Immune response" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 67: Plasma cells - Plasma cell differentiation" 8 "HPA039545: " "unprognostic (5.29e-2)" "unprognostic (1.31e-3)" "unprognostic (1.86e-2)" "unprognostic (4.86e-2)" "unprognostic (1.19e-1)" "unprognostic (5.71e-2)" "unprognostic (1.67e-1)" "unprognostic (8.12e-2)" "unprognostic (6.58e-2)" "unprognostic (7.96e-2)" "potential prognostic favorable (3.23e-6)" "unprognostic (1.60e-1)" "unprognostic (2.86e-2)" "unprognostic (7.51e-2)" "unprognostic (1.15e-1)" "unprognostic (1.64e-1)" "unprognostic (6.55e-2)" "unprognostic (1.23e-1)" "unprognostic (3.17e-1)" "unprognostic (7.54e-2)" "unprognostic (7.93e-3)" "unprognostic (3.44e-2)" "unprognostic (8.14e-3)" "unprognostic (2.06e-1)" "unprognostic (2.86e-3)" "unprognostic (5.75e-2)" "unprognostic (3.67e-2)" "unprognostic (7.62e-2)" "unprognostic (1.11e-1)" "unprognostic (2.47e-1)" "unprognostic (5.32e-2)" TAPT1 FLJ90013 ENSG00000169762 "Transmembrane anterior posterior transformation 1" Q6NXT6 4 16160505-16227410 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Chondrogenesis, Cilium biogenesis/degradation, Differentiation, Host-virus interaction, Osteogenesis" "Developmental protein, Receptor" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 299.4;Myonuclei: 204.1;Neutrophil progenitors: 230.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Pancreas - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042567 Approved Supported "Nucleoplasm,Centrosome,Basal body,Cytosol" NA NA "Cluster 32: Basophils - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 4 "Centrosome, Basal body" "Nucleoplasm, Cytosol" "HPA042567: " "potential prognostic favorable (4.72e-4)" "unprognostic (1.48e-1)" "unprognostic (1.69e-2)" "unprognostic (2.48e-1)" "unprognostic (1.58e-2)" "unprognostic (8.90e-2)" "unprognostic (2.33e-1)" "unprognostic (5.77e-3)" "unprognostic (5.53e-2)" "unprognostic (2.25e-1)" "validated prognostic favorable (4.38e-6)" "validated prognostic favorable (2.10e-6)" "unprognostic (6.68e-3)" "unprognostic (1.21e-2)" "potential prognostic favorable (1.50e-4)" "potential prognostic favorable (3.20e-4)" "unprognostic (1.88e-1)" "unprognostic (6.55e-2)" "unprognostic (2.48e-1)" "unprognostic (3.22e-2)" "unprognostic (1.33e-1)" "potential prognostic favorable (1.80e-4)" "unprognostic (4.59e-3)" "unprognostic (6.78e-2)" "unprognostic (3.14e-2)" "unprognostic (9.81e-2)" "unprognostic (1.30e-1)" "unprognostic (1.59e-1)" "unprognostic (5.15e-2)" "unprognostic (1.35e-3)" "unprognostic (5.09e-2)" TARBP1 "TRM3, TRMT3, TRP-185" ENSG00000059588 "TAR (HIV-1) RNA binding protein 1" Q13395 1 234391313-234479179 "Predicted intracellular proteins" "tRNA processing" "Methyltransferase, RNA-binding, Transferase, tRNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 248.7;Brain inhibitory neurons: 248.3;Other brain neurons: 205.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020810, HPA024632" Uncertain Approved "Nuclear speckles" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 61: Non-specific - Transcription" "Cluster 9: Non-specific - Receptor signaling" "Cluster 45: Non-specific - Nuclear processes" "Cluster 35: Neurons - Synaptic function & neurogenesis" 2 "Nuclear speckles" "CAB020810: , HPA024632: " "unprognostic (1.84e-1)" "unprognostic (2.45e-1)" "unprognostic (2.69e-1)" "potential prognostic unfavorable (2.08e-4)" "unprognostic (2.12e-1)" "unprognostic (4.19e-1)" "unprognostic (2.13e-1)" "potential prognostic favorable (1.62e-4)" "unprognostic (9.81e-3)" "unprognostic (1.40e-1)" "unprognostic (2.65e-3)" "unprognostic (5.96e-1)" "unprognostic (7.00e-2)" "unprognostic (4.42e-2)" "unprognostic (7.40e-2)" "unprognostic (1.16e-1)" "unprognostic (2.08e-1)" "unprognostic (1.26e-1)" "unprognostic (4.65e-2)" "unprognostic (2.03e-1)" "unprognostic (3.02e-2)" "unprognostic (1.18e-1)" "unprognostic (7.39e-2)" "unprognostic (9.17e-2)" "unprognostic (1.46e-3)" "unprognostic (1.37e-1)" "unprognostic (9.38e-2)" "unprognostic (2.87e-1)" "unprognostic (3.38e-1)" "unprognostic (3.27e-2)" "unprognostic (3.20e-1)" TARBP2 Trbp ENSG00000139546 "TARBP2 subunit of RISC loading complex" Q15633 12 53500921-53506431 "Predicted intracellular proteins" "RNA-mediated gene silencing, Translation regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 54.7;Extravillous trophoblasts: 57.6;Late spermatids: 42.1;Migrating cytotrophoblasts: 55.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells, Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051181, HPA061454, CAB069406" Approved Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 64: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 42 Nucleoplasm "Nuclear bodies" "CAB069406: , HPA051181: , HPA061454: " "unprognostic (3.22e-2)" "unprognostic (1.41e-1)" "unprognostic (3.08e-1)" "unprognostic (9.47e-2)" "unprognostic (1.21e-1)" "unprognostic (1.14e-1)" "unprognostic (7.84e-2)" "unprognostic (1.67e-2)" "unprognostic (9.42e-2)" "unprognostic (1.21e-2)" "validated prognostic unfavorable (1.41e-6)" "validated prognostic unfavorable (5.27e-4)" "unprognostic (1.41e-1)" "validated prognostic unfavorable (9.33e-5)" "validated prognostic unfavorable (7.63e-5)" "unprognostic (1.48e-2)" "unprognostic (1.45e-2)" "unprognostic (3.27e-2)" "unprognostic (1.56e-1)" "unprognostic (5.21e-2)" "unprognostic (2.18e-1)" "unprognostic (3.11e-1)" "unprognostic (2.80e-3)" "unprognostic (4.86e-1)" "unprognostic (1.79e-1)" "unprognostic (2.80e-1)" "unprognostic (2.25e-3)" "unprognostic (5.43e-2)" "unprognostic (1.33e-1)" "unprognostic (2.01e-2)" "unprognostic (1.59e-1)" TARDBP "ALS10, TDP-43" ENSG00000120948 "TAR DNA binding protein" Q13148 1 11012344-11030528 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "DNA-binding, Repressor, RNA-binding" "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003703, HPA017284" Supported Enhanced Nucleoplasm NA NA 220000 "Cluster 30: Non-specific - DNA binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 238 Nucleoplasm "CAB003703: , HPA017284: " "unprognostic (3.05e-3)" "unprognostic (2.45e-1)" "unprognostic (8.17e-2)" "unprognostic (2.91e-1)" "unprognostic (5.85e-3)" "unprognostic (3.67e-1)" "unprognostic (4.97e-2)" "unprognostic (3.09e-1)" "unprognostic (9.10e-2)" "potential prognostic unfavorable (4.57e-5)" "potential prognostic favorable (8.57e-5)" "unprognostic (2.21e-3)" "unprognostic (1.31e-1)" "potential prognostic unfavorable (2.68e-8)" "unprognostic (5.52e-3)" "unprognostic (7.42e-3)" "unprognostic (2.50e-3)" "unprognostic (3.49e-2)" "unprognostic (5.69e-2)" "unprognostic (3.39e-1)" "unprognostic (1.38e-1)" "unprognostic (3.44e-2)" "unprognostic (5.66e-3)" "unprognostic (3.70e-1)" "unprognostic (3.01e-1)" "unprognostic (4.88e-2)" "unprognostic (6.89e-2)" "unprognostic (8.24e-2)" "unprognostic (1.94e-1)" "unprognostic (5.00e-2)" "unprognostic (1.92e-1)" TARM1 ENSG00000248385 "T cell-interacting, activating receptor on myeloid cells 1" B6A8C7 19 54069895-54081365 "Predicted membrane proteins" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 19 "bone marrow: 6.6" "Cell type enriched" "Detected in single" 6 "Neutrophil progenitors: 3.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Lung - Neutrophils_1, Spleen - Neutrophils_1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA051022, HPA054401" Uncertain NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 15: Bone marrow - Innate immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" "HPA051022: , HPA054401: " TARP ENSG00000289746 "TCR gamma alternate reading frame protein" 7 38259643-38273636 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "bone marrow: 40.2;prostate: 153.6" "Cell type enhanced" "Detected in some" "Innate lymphoid cells: 44.8;Monocyte progenitors: 14.6;Neutrophil progenitors: 35.7;NK-cells: 65.3;Prostatic glandular cells: 71.5;T-cells: 26.0;Thymocytes: 23.7" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 5 "gdT-cell: 1208.2" "Lineage enriched" "Detected in many" 5 "T-cells: 1208.2" "Cancer enriched" "Detected in some" 6 "prostate cancer: 139.8" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 47: Endothelial cells - Vasculature" "Cluster 60: Prostate cancer - Unknown function" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" TARS1 TARS ENSG00000113407 "Threonyl-tRNA synthetase 1" P26639 5 33440696-33468091 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase, RNA-binding, tRNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037425 Approved Approved "Actin filaments,Cytosol" NA NA 1300000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 29: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 16 Cytosol "Actin filaments" "HPA037425: " "unprognostic (4.78e-2)" "unprognostic (1.29e-2)" "unprognostic (1.11e-2)" "unprognostic (1.88e-1)" "unprognostic (1.09e-2)" "unprognostic (1.02e-2)" "unprognostic (3.42e-1)" "unprognostic (1.06e-2)" "potential prognostic unfavorable (4.79e-4)" "potential prognostic favorable (1.14e-7)" "unprognostic (1.35e-1)" "unprognostic (6.14e-2)" "unprognostic (3.15e-3)" "unprognostic (1.16e-2)" "potential prognostic unfavorable (2.30e-4)" "unprognostic (2.01e-1)" "unprognostic (3.12e-1)" "unprognostic (1.03e-1)" "unprognostic (2.25e-1)" "unprognostic (1.77e-2)" "potential prognostic unfavorable (7.55e-6)" "unprognostic (2.63e-3)" "unprognostic (1.46e-2)" "unprognostic (1.71e-1)" "unprognostic (2.27e-1)" "unprognostic (9.84e-2)" "unprognostic (1.08e-1)" "unprognostic (2.02e-2)" "unprognostic (3.87e-1)" TARS2 "FLJ12528, TARSL1" ENSG00000143374 "Threonyl-tRNA synthetase 2, mitochondrial" Q9BW92 1 150487414-150507602 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028626 Approved Uncertain Nucleoplasm,Cytosol NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 51: Secretory epithelial cells - Mixed function" 48 "Nucleoplasm, Cytosol" "HPA028626: " "unprognostic (5.83e-2)" "unprognostic (5.64e-2)" "unprognostic (2.96e-2)" "unprognostic (1.50e-1)" "unprognostic (9.12e-2)" "unprognostic (6.48e-3)" "unprognostic (7.26e-2)" "unprognostic (8.79e-2)" "unprognostic (2.24e-1)" "unprognostic (3.51e-3)" "unprognostic (1.05e-2)" "unprognostic (2.06e-1)" "unprognostic (1.86e-1)" "unprognostic (5.76e-3)" "unprognostic (2.14e-1)" "unprognostic (1.33e-2)" "unprognostic (5.19e-3)" "unprognostic (1.65e-1)" "unprognostic (5.08e-2)" "unprognostic (8.32e-2)" "unprognostic (1.89e-1)" "unprognostic (1.49e-2)" "unprognostic (1.03e-1)" "unprognostic (2.98e-1)" "unprognostic (1.20e-1)" "unprognostic (4.01e-2)" "unprognostic (1.28e-2)" "unprognostic (3.54e-2)" "unprognostic (1.73e-1)" "unprognostic (1.43e-1)" "unprognostic (2.50e-2)" TARS3 "FLJ25005, TARSL2, ThrRS-L" ENSG00000185418 "Threonyl-tRNA synthetase 3" A2RTX5 15 101653596-101724473 "Enzymes, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 36.0;tongue: 34.1" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 272.3;Thymocytes: 238.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066697 Enhanced Approved Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 54: Non-specific - Transcription" "Cluster 9: T-cells - Adaptive immunity: Regulation" 8 Cytosol "HPA066697: " "unprognostic (1.59e-1)" "unprognostic (1.87e-2)" "unprognostic (2.27e-2)" "unprognostic (4.96e-2)" "unprognostic (1.45e-2)" "unprognostic (3.46e-1)" "unprognostic (6.89e-2)" "unprognostic (5.16e-2)" "unprognostic (1.90e-2)" "validated prognostic favorable (3.81e-5)" "validated prognostic favorable (5.06e-4)" "unprognostic (5.92e-2)" "unprognostic (1.21e-1)" "unprognostic (2.48e-1)" "unprognostic (2.65e-1)" "unprognostic (1.46e-2)" "unprognostic (2.95e-1)" "unprognostic (2.39e-1)" "unprognostic (3.15e-1)" "unprognostic (1.99e-1)" "unprognostic (1.55e-1)" "unprognostic (1.79e-1)" "unprognostic (9.02e-2)" "unprognostic (2.08e-1)" "unprognostic (2.10e-2)" "unprognostic (1.82e-1)" "unprognostic (8.45e-2)" "unprognostic (6.63e-3)" "unprognostic (4.80e-2)" TAS1R1 "GPR70, T1R1, TR1" ENSG00000173662 "Taste 1 receptor member 1" Q7RTX1 1 6555307-6579755 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 5 "testis: 4.2" "Cell type enhanced" "Detected in many" "Early spermatids: 11.6;Endometrial glandular cells: 12.8;Endometrial luminal cells: 30.6;Endometrial secretory cells: 17.2;Epididymal basal cells: 12.5;Late spermatids: 30.2;Müller glia: 10.9;Myonuclei: 19.2;Thymic myoid cells: 9.5;Tuft cells: 11.5" "Cell type enhanced" "Detected in some" "ependymal cell: 4.1" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Myeloma: 1.7" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA034579, HPA034580" Approved NA NA "Cluster 47: Testis - Mixed function" "Cluster 46: Brainstem - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 51: Secretory epithelial cells - Mixed function" "HPA034579: , HPA034580: " "unprognostic (3.17e-2)" TAS1R2 "GPR71, T1R2, TR2" ENSG00000179002 "Taste 1 receptor member 2" Q8TE23 1 18839599-18859660 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Breast myoepithelial cells: 3.4;Salivary basal cells: 4.0;Salivary myoepithelial cells: 3.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 82: Dendritic cells - Antigen presentation" TAS1R3 T1R3 ENSG00000169962 "Taste 1 receptor member 3" Q7RTX0 1 1331280-1335314 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "epididymis: 11.5;lymphoid tissue: 3.4;salivary gland: 7.4" "Group enriched" "Detected in some" 10 "Epididymal principal cells: 81.4;Tuft cells: 149.9" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 17 "memory B-cell: 1.6" "Lineage enriched" "Detected in single" 17 "B-cells: 1.6" "Cancer enhanced" "Detected in some" "Myeloma: 7.0" "Breast - Plasma cells, Minor Salivary Gland - Plasma cells, Spleen - Plasma cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA053439 Uncertain Supported "Golgi apparatus,Plasma membrane" NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 22: Epididymis - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" "Plasma membrane" "Golgi apparatus" "HPA053439: " "unprognostic (5.59e-3)" "unprognostic (6.29e-2)" "unprognostic (1.29e-1)" "unprognostic (8.35e-2)" "unprognostic (2.21e-2)" "unprognostic (1.45e-1)" "unprognostic (2.08e-2)" "unprognostic (3.43e-1)" "unprognostic (3.16e-1)" "potential prognostic favorable (6.68e-4)" "unprognostic (8.49e-2)" "unprognostic (3.84e-3)" TAS2R1 "T2R1, TRB7" ENSG00000169777 "Taste 2 receptor member 1" Q9NYW7 5 9627347-9712378 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 17 "testis: 7.0" "Group enriched" "Detected in some" 24 "Early spermatids: 27.1;Late spermatids: 56.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA051879 Uncertain NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 33: Neurons - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" "HPA051879: " TAS2R10 "T2R10, TRB2" ENSG00000121318 "Taste 2 receptor member 10" Q9NYW0 12 10825219-10826358 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA070201 Approved "Vesicles,Plasma membrane,Actin filaments" NA NA "Cluster 9: Non-specific - Receptor signaling" "Cluster 24: Non-specific - Unknown function" 4 "Vesicles, Plasma membrane" "Actin filaments" "HPA070201: " "unprognostic (2.74e-1)" "unprognostic (6.89e-2)" TAS2R13 "T2R13, TRB3" ENSG00000212128 "Taste 2 receptor member 13" Q9NYV9 12 10907926-10909562 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 9: Non-specific - Receptor signaling" "unprognostic (8.55e-2)" "unprognostic (3.66e-3)" TAS2R14 "T2R14, TRB1" ENSG00000212127 "Taste 2 receptor member 14" Q9NYV8 12 10937408-11171573 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bergmann glia: 1.5;Innate lymphoid cells: 1.2;Oligodendrocyte progenitor cells: 1.1;Oligodendrocytes: 1.1" "Low cell type specificity" "Detected in some" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" NA NA "Cluster 64: Non-specific - Transcription" "Cluster 46: Brainstem - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 98: Neurons - Neurotransmission & signaling" 3 "unprognostic (1.24e-2)" "unprognostic (7.83e-2)" "unprognostic (6.67e-3)" "unprognostic (1.70e-1)" "unprognostic (3.20e-1)" "potential prognostic unfavorable (3.68e-6)" TAS2R16 T2R16 ENSG00000128519 "Taste 2 receptor member 16" Q9NYV7 7 122994704-122995700 "G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA TAS2R19 "T2R19, T2R23, TAS2R23, TAS2R48" ENSG00000212124 "Taste 2 receptor member 19" P59542 12 11021619-11022620 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 64: Non-specific - Transcription" "Cluster 30: White matter - Myelination" 6 "unprognostic (1.90e-2)" "unprognostic (2.69e-2)" "potential prognostic unfavorable (6.60e-4)" TAS2R20 "T2R20, T2R56, TAS2R49" ENSG00000255837 "Taste 2 receptor member 20" P59543 12 10995961-10998304 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in some" NA NA "Cluster 64: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 56: Non-specific - Sensory perception" 1 "unprognostic (3.01e-1)" "unprognostic (1.25e-1)" "unprognostic (2.21e-2)" "unprognostic (1.91e-3)" TAS2R3 T2R3 ENSG00000127362 "Taste 2 receptor member 3" Q9NYW6 7 141764097-141765197 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 56: Non-specific - Sensory perception" "unprognostic (4.93e-1)" "unprognostic (3.52e-2)" "unprognostic (3.74e-2)" "unprognostic (2.75e-1)" TAS2R30 "T2R30, TAS2R47" ENSG00000256188 "Taste 2 receptor member 30" P59541 12 11132958-11134644 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 56: Non-specific - Sensory perception" "unprognostic (2.47e-1)" "unprognostic (2.29e-2)" "unprognostic (3.87e-3)" "unprognostic (1.18e-2)" TAS2R31 "T2R31, T2R53, TAS2R44" ENSG00000256436 "Taste 2 receptor member 31" P59538 12 11030387-11031407 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 56: Non-specific - Sensory perception" 1 "unprognostic (2.03e-1)" "unprognostic (1.44e-2)" "potential prognostic unfavorable (9.65e-4)" TAS2R38 "PTC, T2R61" ENSG00000257138 "Taste 2 receptor member 38" P59533 7 141972631-141973773 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 2.0;lung cancer: 1.1" "Not detected" "Not detected" "HPA043862, HPA054366" Uncertain NA NA "Cluster 24: Non-specific - Unknown function" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" "HPA043862: , HPA054366: " "unprognostic (5.49e-2)" "unprognostic (6.52e-2)" TAS2R39 ENSG00000236398 "Taste 2 receptor member 39" P59534 7 143183419-143184435 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA060680 Uncertain NA NA "Cluster 30: White matter - Myelination" "Cluster 80: Oligodendrocytes - Myelination" "HPA060680: " TAS2R4 T2R4 ENSG00000127364 "Taste 2 receptor member 4" Q9NYW5 7 141776674-141781691 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 64: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 56: Non-specific - Sensory perception" "unprognostic (9.96e-2)" "unprognostic (2.82e-1)" "unprognostic (1.76e-2)" "unprognostic (2.45e-2)" "unprognostic (5.47e-2)" TAS2R40 GPR60 ENSG00000221937 "Taste 2 receptor member 40" P59535 7 143222037-143223079 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 11 "neutrophil: 2.8" "Lineage enriched" "Detected in single" 11 "granulocytes: 2.8" "Not detected" "Not detected" "Adipose visceral - Neutrophils, Lung - Neutrophils_2, Spleen - Neutrophils_2" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 30: White matter - Myelination" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" TAS2R41 T2R59 ENSG00000221855 "Taste 2 receptor member 41" P59536 7 143477873-143478796 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA057063 Uncertain NA NA 1 "HPA057063: " TAS2R42 "hT2R55, T2R24, T2R55, TAS2R55" ENSG00000186136 "Taste 2 receptor member 42" Q7RTR8 12 11185993-11186937 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA036149 Uncertain NA NA "Cluster 24: Non-specific - Unknown function" "HPA036149: " TAS2R43 T2R52 ENSG00000255374 "Taste 2 receptor member 43" P59537 12 11091287-11092313 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 60: Prostate cancer - Unknown function" "unprognostic (1.50e-1)" "unprognostic (4.27e-3)" TAS2R46 T2R54 ENSG00000226761 "Taste 2 receptor member 46" P59540 12 11061365-11062294 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 30: White matter - Myelination" "unprognostic (4.40e-2)" "potential prognostic unfavorable (7.78e-4)" TAS2R5 T2R5 ENSG00000127366 "Taste 2 receptor member 5" Q9NYW4 7 141790217-141791367 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Epicardial cells: 2.3;Kupffer cells: 1.0" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" HPA053742 Approved "Nucleoplasm,Nucleoli,Cytoplasmic bodies" NA NA "Cluster 64: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 56: Non-specific - Sensory perception" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 6 "Nucleoplasm, Nucleoli" "Cytoplasmic bodies" "HPA053742: " "unprognostic (5.61e-3)" "unprognostic (1.30e-2)" "unprognostic (8.69e-2)" "unprognostic (7.81e-2)" "unprognostic (3.84e-3)" "unprognostic (7.61e-2)" "unprognostic (1.01e-2)" "unprognostic (1.27e-1)" "unprognostic (1.03e-1)" "unprognostic (2.36e-3)" "potential prognostic favorable (7.62e-4)" "unprognostic (2.60e-1)" TAS2R50 T2R51 ENSG00000212126 "Taste 2 receptor member 50" P59544 12 10985913-10986912 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 9: Non-specific - Receptor signaling" "unprognostic (6.89e-2)" "unprognostic (5.53e-3)" TAS2R60 T2R60 ENSG00000185899 "Taste 2 receptor member 60" P59551 7 143443453-143444409 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA030416 Uncertain NA NA "Cluster 24: Non-specific - Unknown function" "HPA030416: " TAS2R7 "T2R7, TRB4" ENSG00000121377 "Taste 2 receptor member 7" Q9NYW3 12 10801532-10802627 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 109: Neurons - Neuronal signaling" 1 TAS2R8 "T2R8, TRB5" ENSG00000121314 "Taste 2 receptor member 8" Q9NYW2 12 10806051-10807286 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 109: Neurons - Neuronal signaling" 2 "unprognostic (1.56e-1)" TAS2R9 "T2R9, TRB6" ENSG00000121381 "Taste 2 receptor member 9" Q9NYW1 12 10809094-10810168 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 53: Neurons - Mixed function" "Cluster 109: Neurons - Neuronal signaling" "unprognostic (9.33e-2)" TASL "CXorf21, FLJ11577" ENSG00000120280 "TLR adaptor interacting with endolysosomal SLC15A4" Q9HAI6 X 30558809-30577766 "Disease related genes, Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 18.4;lymphoid tissue: 10.2" "Cell type enhanced" "Detected in some" "cDC: 66.3;Hofbauer cells: 35.2;Kupffer cells: 29.7;Macrophages: 43.6;Microglia: 35.4;Monocyte progenitors: 149.0;monocytes: 48.2;Neutrophil progenitors: 32.5;Neutrophils: 58.6;pDCs: 71.4;Plasma cells: 61.3;Thymocytes: 36.4" "Cell type enriched" "Detected in some" 5 "central nervous system macrophage: 43.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 86 "Leukemia: 43.1;lymphoma: 17.3;Myeloma: 20.4" "Adrenal gland - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA001185 Uncertain Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 6: Leukemia - Signal transduction" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 8 Nucleoplasm "Vesicles, Cytosol" "HPA001185: " "unprognostic (3.85e-2)" "unprognostic (3.74e-1)" "unprognostic (5.15e-2)" "unprognostic (8.76e-3)" "unprognostic (1.54e-1)" "unprognostic (1.40e-1)" "unprognostic (5.78e-3)" "unprognostic (3.46e-2)" "unprognostic (1.44e-1)" "unprognostic (3.37e-1)" "unprognostic (1.99e-1)" "potential prognostic favorable (1.64e-5)" "unprognostic (4.95e-2)" "unprognostic (1.73e-1)" "unprognostic (1.91e-1)" "unprognostic (1.96e-1)" "unprognostic (6.40e-2)" "unprognostic (2.31e-1)" "unprognostic (2.63e-2)" "unprognostic (1.38e-2)" "unprognostic (1.71e-1)" "unprognostic (1.39e-1)" "unprognostic (8.33e-3)" "unprognostic (2.94e-2)" "unprognostic (3.66e-3)" TASOR "C3orf63, FAM208A, KIAA1105, RAP140, se89-1, TASOR1" ENSG00000163946 "Transcription activation suppressor" Q9UK61 3 56620132-56683265 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006735, HPA017142" Uncertain Enhanced Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Transcription" 12 Nucleoplasm "HPA006735: , HPA017142: " "unprognostic (1.71e-1)" "unprognostic (3.13e-1)" "unprognostic (4.04e-2)" "unprognostic (4.00e-2)" "unprognostic (3.86e-2)" "unprognostic (1.08e-1)" "unprognostic (2.85e-1)" "unprognostic (6.72e-3)" "unprognostic (1.26e-2)" "potential prognostic favorable (1.90e-7)" "unprognostic (1.07e-2)" "unprognostic (2.38e-1)" "unprognostic (6.81e-2)" "unprognostic (1.19e-1)" "unprognostic (2.48e-3)" "unprognostic (7.18e-2)" "unprognostic (2.56e-1)" "unprognostic (1.15e-1)" "unprognostic (2.24e-1)" "unprognostic (3.11e-2)" "unprognostic (3.31e-2)" "unprognostic (7.97e-2)" "unprognostic (4.74e-3)" "unprognostic (1.82e-1)" "unprognostic (3.48e-1)" "unprognostic (1.32e-1)" "unprognostic (2.15e-1)" "unprognostic (3.73e-2)" "unprognostic (5.46e-3)" TASOR2 "bA318E3.2, C10orf18, FAM208B, FLJ20360, KIAA2006" ENSG00000108021 "Transcription activation suppressor family member 2" Q5VWN6 10 5684731-5763779 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038042, HPA038043, HPA061547" Uncertain Enhanced Nucleoplasm,Cytosol NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 61: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 17: Non-specific - RNA processing" 43 Nucleoplasm Cytosol "HPA038042: , HPA038043: , HPA061547: " "unprognostic (3.02e-1)" "unprognostic (3.03e-2)" "potential prognostic unfavorable (9.03e-4)" "unprognostic (1.22e-1)" "unprognostic (2.61e-1)" "unprognostic (7.39e-3)" "potential prognostic favorable (5.61e-6)" "unprognostic (5.44e-2)" "unprognostic (5.66e-3)" "potential prognostic favorable (4.91e-4)" "unprognostic (8.09e-2)" "unprognostic (3.76e-2)" "unprognostic (1.54e-3)" "unprognostic (1.10e-1)" "unprognostic (7.63e-3)" "unprognostic (9.84e-2)" "unprognostic (3.06e-1)" "unprognostic (2.34e-1)" "unprognostic (1.42e-3)" "unprognostic (9.27e-3)" "unprognostic (7.88e-3)" "unprognostic (4.74e-2)" "unprognostic (8.15e-3)" "unprognostic (1.63e-2)" "unprognostic (2.31e-1)" "unprognostic (1.45e-2)" "unprognostic (1.89e-1)" "unprognostic (1.64e-3)" "unprognostic (1.65e-1)" TASP1 "C20orf13, dJ585I14.2, FLJ20212" ENSG00000089123 "Taspase 1" Q9H6P5 20 13389392-13638932 "Disease related genes, Predicted intracellular proteins" "Hydrolase, Protease, Threonine protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 27.3" "Cell type enriched" "Detected in all" 4 "Thymocytes: 1666.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast myoepithelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030824, HPA030825" Uncertain Approved "Plasma membrane" No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" "Plasma membrane" "HPA030824: , HPA030825: " "unprognostic (6.97e-2)" "unprognostic (1.39e-1)" "unprognostic (2.38e-1)" "unprognostic (2.22e-1)" "unprognostic (1.43e-1)" "unprognostic (1.58e-1)" "unprognostic (3.19e-1)" "unprognostic (8.22e-2)" "unprognostic (8.41e-2)" "unprognostic (4.77e-2)" "unprognostic (1.13e-3)" "unprognostic (1.16e-2)" "unprognostic (1.30e-1)" "potential prognostic unfavorable (8.16e-4)" "unprognostic (1.50e-3)" "unprognostic (1.25e-1)" "unprognostic (3.23e-1)" "unprognostic (3.98e-2)" "unprognostic (2.33e-1)" "unprognostic (5.91e-3)" "unprognostic (2.75e-1)" "unprognostic (3.22e-1)" "potential prognostic unfavorable (3.37e-4)" "unprognostic (3.36e-1)" "unprognostic (2.65e-2)" "unprognostic (3.93e-2)" "unprognostic (9.25e-2)" "unprognostic (2.67e-1)" "unprognostic (1.45e-1)" "unprognostic (7.06e-3)" "unprognostic (4.28e-2)" TAT ENSG00000198650 "Tyrosine aminotransferase" P17735 16 71565660-71577092 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Phenylalanine catabolism, Tyrosine catabolism" "Aminotransferase, Transferase" "Disease variant, Intellectual disability, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "liver: 1188.4" "Cell type enriched" "Detected in some" 30 "Hepatocytes: 5253.2" "Cell type enriched" "Detected in single" 4 "Bergmann glia: 1.5" "Cancer enriched" "Detected in some" 8 "Liver Hepatocellular Carcinoma (TCGA): 253.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "breast cancer: 1.4" "Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 9: Non-specific - Receptor signaling" "Cluster 27: Breast cancer - Unknown function" "Cluster 93: Hepatocytes - Bile production & excretion" 7 "unprognostic (5.97e-3)" "unprognostic (1.35e-1)" "validated prognostic favorable (9.11e-4)" "validated prognostic favorable (2.46e-5)" TATDN1 CDA11 ENSG00000147687 "TatD DNase domain containing 1" Q6P1N9 8 124488485-124539458 "Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 284.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023634, HPA053045" Uncertain Supported Nucleoplasm NA NA 1700000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 6 Nucleoplasm "HPA023634: , HPA053045: " "unprognostic (8.22e-3)" "potential prognostic unfavorable (3.69e-4)" "unprognostic (2.96e-1)" "unprognostic (4.69e-2)" "unprognostic (2.83e-1)" "unprognostic (4.32e-2)" "unprognostic (3.51e-1)" "unprognostic (1.09e-2)" "unprognostic (9.85e-3)" "unprognostic (1.62e-2)" "potential prognostic favorable (1.55e-4)" "unprognostic (1.20e-2)" "unprognostic (1.49e-1)" "potential prognostic unfavorable (4.35e-4)" "unprognostic (1.36e-2)" "potential prognostic unfavorable (6.96e-4)" "unprognostic (6.01e-2)" "unprognostic (9.64e-2)" "unprognostic (2.27e-1)" "unprognostic (4.71e-1)" "unprognostic (3.43e-3)" "potential prognostic unfavorable (1.57e-4)" "unprognostic (1.42e-2)" "unprognostic (6.55e-2)" "unprognostic (2.40e-2)" "unprognostic (3.48e-1)" "unprognostic (1.92e-1)" "unprognostic (2.71e-1)" "unprognostic (2.42e-1)" "unprognostic (8.77e-2)" "unprognostic (1.39e-1)" TATDN2 KIAA0218 ENSG00000157014 "TatD DNase domain containing 2" Q93075 3 10248023-10281218 "Predicted intracellular proteins" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Epididymal clear cells: 2.0;Late spermatids: 1.6;Megakaryocyte progenitors: 1.5;Plasma cells: 1.9;Thymic myoid cells: 4.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036822 Approved Approved "Nuclear speckles" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 54: Non-specific - Ribosome" "Cluster 51: Neurons - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 9: T-cells - Adaptive immunity: Regulation" "Nuclear speckles" "HPA036822: " "unprognostic (4.40e-2)" "unprognostic (1.22e-1)" "unprognostic (6.44e-2)" "unprognostic (2.69e-1)" "unprognostic (7.05e-2)" "unprognostic (1.39e-1)" "unprognostic (2.99e-1)" "unprognostic (5.36e-2)" "unprognostic (2.40e-2)" "potential prognostic unfavorable (4.77e-4)" "unprognostic (1.42e-3)" "unprognostic (2.62e-2)" "unprognostic (1.49e-1)" "unprognostic (2.31e-3)" "unprognostic (5.68e-3)" "unprognostic (1.33e-1)" "unprognostic (3.70e-2)" "unprognostic (1.60e-1)" "unprognostic (1.11e-2)" "unprognostic (6.82e-2)" "unprognostic (2.46e-1)" "unprognostic (2.16e-1)" "unprognostic (5.85e-2)" "unprognostic (1.34e-1)" "unprognostic (2.70e-3)" "unprognostic (1.18e-3)" "unprognostic (2.16e-1)" "unprognostic (1.35e-1)" "unprognostic (2.73e-1)" "unprognostic (1.89e-2)" "unprognostic (2.19e-1)" TATDN3 ENSG00000203705 "TatD DNase domain containing 3" Q17R31 1 212791828-212816830 "Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "pDCs: 148.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032092 Approved Approved "Nucleoplasm,Golgi apparatus,Focal adhesion sites" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 52: Non-specific - Cellular respiration" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 4 Nucleoplasm "Golgi apparatus, Focal adhesion sites" "HPA032092: " "unprognostic (4.00e-1)" "unprognostic (7.94e-2)" "unprognostic (9.16e-2)" "unprognostic (2.83e-1)" "unprognostic (2.09e-1)" "unprognostic (2.93e-2)" "unprognostic (8.65e-2)" "unprognostic (1.88e-2)" "unprognostic (9.77e-2)" "unprognostic (2.06e-3)" "potential prognostic favorable (3.38e-4)" "unprognostic (2.25e-1)" "unprognostic (9.56e-2)" "unprognostic (1.53e-1)" "unprognostic (4.62e-2)" "unprognostic (2.99e-1)" "unprognostic (3.41e-1)" "unprognostic (7.52e-2)" "unprognostic (2.20e-1)" "unprognostic (1.06e-1)" "potential prognostic unfavorable (2.00e-4)" "unprognostic (1.15e-1)" "unprognostic (9.58e-3)" "unprognostic (4.36e-2)" "unprognostic (1.22e-1)" "unprognostic (1.19e-2)" "unprognostic (2.16e-1)" "unprognostic (2.43e-1)" "unprognostic (1.73e-1)" "potential prognostic unfavorable (9.60e-4)" "unprognostic (4.36e-1)" TAX1BP1 "CALCOCO3, TXBP151" ENSG00000106052 "Tax1 binding protein 1" Q86VP1 7 27739331-27844564 "Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Autophagy, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 2242.6;Syncytiotrophoblasts: 1082.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Macrophages, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024432 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 67: Non-specific - Unknown function" "Cluster 84: Apical squamous epithelium - Cornification" 103 Cytosol Nucleoplasm "HPA024432: " "unprognostic (2.96e-1)" "unprognostic (1.53e-2)" "unprognostic (1.90e-2)" "potential prognostic unfavorable (5.84e-5)" "unprognostic (4.58e-2)" "unprognostic (2.28e-1)" "unprognostic (3.76e-1)" "potential prognostic unfavorable (4.91e-4)" "unprognostic (3.85e-3)" "potential prognostic unfavorable (7.92e-5)" "potential prognostic favorable (7.50e-6)" "unprognostic (2.32e-2)" "unprognostic (5.26e-2)" "unprognostic (4.14e-3)" "unprognostic (2.23e-2)" "unprognostic (2.38e-2)" "unprognostic (1.31e-1)" "unprognostic (2.77e-1)" "unprognostic (1.22e-1)" "unprognostic (5.59e-2)" "unprognostic (5.27e-2)" "unprognostic (2.31e-3)" "unprognostic (1.15e-1)" "unprognostic (3.74e-1)" "unprognostic (3.00e-1)" "unprognostic (8.59e-2)" "unprognostic (2.89e-2)" "unprognostic (1.33e-1)" "unprognostic (1.74e-2)" "unprognostic (1.94e-1)" "unprognostic (1.19e-1)" TAX1BP3 TIP-1 ENSG00000213977 "Tax1 binding protein 3" O14907 17 3662895-3668679 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 338.0;Decidual stromal cells: 277.1;Enterocytes: 268.4;Esophageal apical cells: 849.8;Esophageal basal cells: 338.3;Esophageal suprabasal cells: 557.4;Platelets: 339.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 164.7;granulocytes: 218.6;monocytes: 78.9" "Low cancer specificity" "Detected in all" "Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046410, HPA063078" Approved Supported "Nucleoli fibrillar center,Vesicles,Actin filaments" NA NA 150000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 18 "Nucleoli fibrillar center, Actin filaments" Vesicles "HPA046410: , HPA063078: " "unprognostic (1.39e-1)" "unprognostic (3.20e-2)" "unprognostic (7.08e-2)" "unprognostic (3.50e-2)" "unprognostic (8.99e-2)" "unprognostic (1.30e-1)" "potential prognostic unfavorable (3.34e-6)" "unprognostic (1.97e-2)" "unprognostic (5.29e-1)" "unprognostic (3.73e-1)" "unprognostic (3.58e-3)" "unprognostic (7.88e-2)" "unprognostic (2.25e-3)" "unprognostic (4.94e-3)" "unprognostic (1.04e-1)" "unprognostic (1.68e-3)" "unprognostic (4.65e-2)" "unprognostic (6.18e-3)" "unprognostic (2.50e-2)" "unprognostic (4.31e-2)" "unprognostic (4.78e-2)" "unprognostic (2.33e-2)" "unprognostic (2.27e-2)" "unprognostic (1.16e-1)" "unprognostic (1.58e-1)" "unprognostic (3.26e-1)" "unprognostic (1.09e-2)" "unprognostic (5.54e-2)" "unprognostic (3.31e-1)" "unprognostic (3.99e-2)" "unprognostic (7.30e-2)" TBATA "C10orf27, FLJ32820, spatial" ENSG00000166220 "Thymus, brain and testes associated" Q96M53 10 70771238-70785401 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "lymphoid tissue: 119.9" "Group enriched" "Detected in some" 4 "Early spermatids: 148.9;Late spermatids: 545.6" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 19 "Kidney Chromophobe (TCGA): 2.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Region enhanced" "Detected in many" "cerebellum: 21.0" "Low region specificity" "Detected in single" NA NA "Cluster 80: Thymus - Adaptive immune response" "Cluster 27: Breast cancer - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 1 "unprognostic (9.67e-2)" TBC1D1 "KIAA1108, TBC, TBC1" ENSG00000065882 "TBC1 domain family member 1" Q86TI0 4 37891084-38139175 "Predicted intracellular proteins, Transporters" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 996.1;Podocytes: 426.1;Renal collecting duct intercalated cells: 835.4;Salivary ionocytes: 464.7;Vascular smooth muscle cells: 621.0" "Cell type enhanced" "Detected in all" "vascular associated smooth muscle cell: 793.3" "Cancer enriched" "Detected in all" 5 "Kidney Chromophobe (TCGA): 243.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Breast - Endothelial cells, Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041816, HPA058158" Approved Supported Nucleoli NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 51 Nucleoli "HPA041816: , HPA058158: " "unprognostic (7.55e-3)" "unprognostic (1.58e-1)" "unprognostic (4.50e-2)" "unprognostic (1.75e-2)" "unprognostic (2.28e-2)" "unprognostic (1.83e-2)" "unprognostic (1.16e-1)" "unprognostic (6.19e-2)" "unprognostic (1.25e-1)" "unprognostic (9.56e-3)" "validated prognostic favorable (4.38e-8)" "validated prognostic favorable (3.74e-5)" "unprognostic (1.81e-1)" "unprognostic (3.14e-2)" "unprognostic (2.70e-3)" "unprognostic (3.54e-2)" "unprognostic (3.67e-2)" "potential prognostic unfavorable (9.30e-4)" "unprognostic (9.12e-2)" "unprognostic (1.77e-1)" "unprognostic (3.92e-2)" "unprognostic (1.51e-1)" "unprognostic (8.72e-2)" "unprognostic (3.24e-1)" "unprognostic (2.33e-1)" "potential prognostic favorable (3.87e-4)" "potential prognostic unfavorable (6.68e-4)" "unprognostic (1.82e-1)" "unprognostic (2.15e-1)" "unprognostic (2.06e-1)" "unprognostic (6.13e-2)" TBC1D10A "AC004997.C22.2, EPI64, TBC1D10" ENSG00000099992 "TBC1 domain family member 10A" Q9BXI6 22 30291990-30326947 "Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 55.9;Pituicytes/FSCs: 82.9;Proximal tubule cells: 54.5;Rod photoreceptor cells: 82.1" "Cell type enhanced" "Detected in all" "leukocyte: 42.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007725, HPA008142, HPA076041" Approved Enhanced "Plasma membrane" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 66: Non-specific - Mitochondria" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 10 "Plasma membrane" "HPA007725: , HPA008142: , HPA076041: " "unprognostic (7.40e-2)" "unprognostic (4.36e-1)" "unprognostic (2.55e-2)" "unprognostic (1.51e-1)" "unprognostic (5.65e-2)" "unprognostic (2.31e-2)" "unprognostic (3.94e-3)" "unprognostic (7.10e-3)" "unprognostic (4.27e-2)" "unprognostic (1.14e-1)" "potential prognostic favorable (2.56e-6)" "unprognostic (6.55e-3)" "unprognostic (3.97e-1)" "unprognostic (1.12e-1)" "unprognostic (3.43e-2)" "unprognostic (1.49e-1)" "unprognostic (3.23e-2)" "unprognostic (7.33e-2)" "unprognostic (1.55e-1)" "unprognostic (6.92e-2)" "unprognostic (3.70e-1)" "unprognostic (1.04e-1)" "unprognostic (4.51e-2)" "unprognostic (1.25e-1)" "unprognostic (1.30e-1)" "unprognostic (1.18e-1)" "unprognostic (8.48e-2)" "unprognostic (6.97e-2)" "unprognostic (1.32e-2)" "unprognostic (7.24e-2)" "unprognostic (2.81e-1)" TBC1D10B "DKFZP434P1750, EPI64B, FLJ13130, Rab27A-GAPbeta" ENSG00000169221 "TBC1 domain family member 10B" Q4KMP7 16 30357102-30370494 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 57.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048894 Uncertain NA NA 110000 "Cluster 13: Non-specific - Mitochondria" "Cluster 67: Testis - Mixed function" "Cluster 27: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 7 "HPA048894: " "unprognostic (1.68e-1)" "unprognostic (1.37e-2)" "unprognostic (1.34e-1)" "unprognostic (8.25e-2)" "unprognostic (1.06e-1)" "unprognostic (7.30e-2)" "unprognostic (1.05e-1)" "potential prognostic favorable (1.81e-5)" "unprognostic (6.68e-2)" "unprognostic (2.42e-1)" "potential prognostic favorable (3.02e-6)" "unprognostic (2.65e-1)" "unprognostic (1.36e-1)" "unprognostic (2.00e-3)" "unprognostic (5.47e-3)" "unprognostic (7.83e-3)" "unprognostic (1.78e-2)" "unprognostic (2.20e-2)" "unprognostic (4.41e-1)" "unprognostic (2.00e-1)" "unprognostic (1.03e-1)" "unprognostic (1.05e-1)" "unprognostic (4.98e-2)" "unprognostic (3.20e-2)" "unprognostic (1.02e-2)" "unprognostic (2.91e-1)" "unprognostic (1.71e-1)" "unprognostic (3.41e-2)" "unprognostic (1.32e-1)" "unprognostic (2.38e-2)" "unprognostic (2.28e-1)" TBC1D10C "Carabin, EPI64C, FLJ00332" ENSG00000175463 "TBC1 domain family member 10C" Q8IV04 11 67403915-67410089 "Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 38.1;intestine: 29.7;lymphoid tissue: 68.0" "Cell type enhanced" "Detected in some" "B-cells: 82.6;Innate lymphoid cells: 50.0;Megakaryocytes: 43.3;Neutrophil progenitors: 64.9;Neutrophils: 72.1;NK-cells: 112.2;pDCs: 24.8;Plasma cells: 29.7;T-cells: 109.1" "Cell type enriched" "Detected in some" 50 "leukocyte: 110.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Leukemia: 34.8;lymphoma: 25.7" "Adipose subcutaneous - T-cells, Adrenal gland - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Minor Salivary Gland - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Skin - T-cells, Stomach - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA069743 Enhanced Approved "Nuclear bodies" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 8: Immune cells - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 3 "Nuclear bodies" "HPA069743: " "unprognostic (5.20e-3)" "potential prognostic favorable (4.14e-4)" "unprognostic (2.85e-2)" "potential prognostic favorable (7.92e-4)" "unprognostic (7.77e-2)" "unprognostic (1.54e-1)" "unprognostic (2.33e-3)" "potential prognostic favorable (1.11e-4)" "unprognostic (8.12e-2)" "unprognostic (1.75e-2)" "unprognostic (1.68e-1)" "unprognostic (5.94e-2)" "unprognostic (1.59e-2)" "unprognostic (1.79e-2)" "unprognostic (2.59e-3)" "unprognostic (8.91e-2)" "unprognostic (1.17e-1)" "unprognostic (2.32e-1)" "unprognostic (5.81e-2)" "unprognostic (4.42e-2)" "unprognostic (2.69e-2)" "unprognostic (8.00e-2)" "unprognostic (1.36e-1)" "unprognostic (1.94e-2)" "unprognostic (2.72e-2)" "potential prognostic favorable (2.83e-5)" "unprognostic (1.07e-1)" "unprognostic (1.56e-1)" "unprognostic (1.02e-2)" "unprognostic (2.61e-2)" TBC1D12 KIAA0608 ENSG00000108239 "TBC1 domain family member 12" O60347 10 94402541-94536332 "Cancer-related genes, Predicted intracellular proteins" "GTPase activation" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 41.1" "Cell type enhanced" "Detected in many" "Microglia: 304.7;Oligodendrocytes: 273.6" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 408.5;oligodendrocyte: 463.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Macrophages, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038277, HPA038645" Uncertain Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 52: Non-specific - Mitochondria" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" "Nucleoplasm, Nuclear speckles" "HPA038277: , HPA038645: " "unprognostic (2.61e-2)" "unprognostic (2.22e-2)" "unprognostic (3.39e-1)" "unprognostic (3.44e-1)" "unprognostic (1.25e-3)" "unprognostic (1.96e-1)" "unprognostic (3.30e-2)" "unprognostic (9.05e-3)" "unprognostic (5.41e-2)" "unprognostic (4.42e-2)" "potential prognostic favorable (2.78e-5)" "unprognostic (1.98e-3)" "unprognostic (1.11e-2)" "unprognostic (2.86e-2)" "unprognostic (3.49e-3)" "unprognostic (2.91e-1)" "unprognostic (1.53e-1)" "unprognostic (1.28e-1)" "unprognostic (2.93e-1)" "potential prognostic unfavorable (9.23e-4)" "unprognostic (2.65e-2)" "unprognostic (1.27e-1)" "unprognostic (2.91e-2)" "unprognostic (2.12e-2)" "unprognostic (2.79e-2)" "unprognostic (1.11e-1)" "unprognostic (7.48e-2)" "unprognostic (2.68e-1)" "unprognostic (1.55e-1)" "unprognostic (1.94e-1)" "unprognostic (2.88e-1)" TBC1D13 FLJ10743 ENSG00000107021 "TBC1 domain family member 13" Q9NVG8 9 128787253-128810430 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 47.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 23.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Skin - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045865, HPA075988" Approved Approved Cytosol NA No 20000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 36: Brain & Liver - Signaling" "Cluster 51: Neurons - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 88: Proximal tubular cells - Transmembrane transport" 5 Cytosol "HPA045865: , HPA075988: " "unprognostic (3.62e-1)" "unprognostic (1.76e-1)" "unprognostic (3.48e-2)" "unprognostic (4.45e-2)" "unprognostic (5.35e-3)" "unprognostic (3.03e-2)" "unprognostic (1.31e-1)" "unprognostic (1.22e-2)" "unprognostic (9.59e-2)" "unprognostic (8.86e-2)" "validated prognostic favorable (1.34e-7)" "validated prognostic favorable (2.71e-4)" "potential prognostic favorable (9.60e-4)" "validated prognostic unfavorable (2.52e-4)" "validated prognostic unfavorable (6.35e-4)" "unprognostic (5.05e-2)" "unprognostic (2.68e-1)" "unprognostic (2.07e-1)" "unprognostic (1.65e-2)" "unprognostic (3.67e-2)" "unprognostic (1.96e-1)" "potential prognostic favorable (8.43e-4)" "unprognostic (2.88e-2)" "unprognostic (1.06e-2)" "unprognostic (6.04e-2)" "unprognostic (3.08e-1)" "unprognostic (3.53e-2)" "unprognostic (7.18e-2)" "unprognostic (9.76e-2)" "unprognostic (6.41e-2)" "unprognostic (3.71e-2)" TBC1D14 KIAA1322 ENSG00000132405 "TBC1 domain family member 14" Q9P2M4 4 6909242-7033118 "Plasma proteins, Predicted intracellular proteins" Autophagy "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Mast cells: 277.5;Neutrophils: 894.7;Renal collecting duct intercalated cells: 872.3" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 6 "Kidney Chromophobe (TCGA): 377.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Macrophages, Adrenal gland - Adrenal cortex cells, Colon - Macrophages, Stomach - Parietal cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036930, HPA067398" Approved Supported "Nucleoplasm,Golgi apparatus,Vesicles" Yes No "Cluster 21: Neutrophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 24: Neutrophils - Innate immunity signal integration" 3 "Golgi apparatus, Vesicles" Nucleoplasm "HPA036930: , HPA067398: " "unprognostic (8.21e-2)" "unprognostic (1.65e-3)" "unprognostic (1.76e-1)" "potential prognostic unfavorable (2.54e-4)" "unprognostic (8.70e-3)" "unprognostic (3.79e-2)" "unprognostic (4.48e-1)" "potential prognostic favorable (1.87e-4)" "unprognostic (1.02e-3)" "unprognostic (3.79e-2)" "potential prognostic favorable (2.27e-6)" "unprognostic (2.22e-3)" "unprognostic (4.19e-3)" "unprognostic (1.58e-2)" "unprognostic (1.65e-1)" "unprognostic (3.66e-2)" "unprognostic (1.48e-3)" "unprognostic (2.84e-2)" "unprognostic (8.38e-2)" "unprognostic (9.59e-2)" "unprognostic (2.65e-1)" "unprognostic (1.92e-3)" "unprognostic (1.57e-1)" "unprognostic (4.20e-2)" "unprognostic (4.96e-3)" "unprognostic (1.29e-1)" "unprognostic (6.60e-2)" "unprognostic (9.83e-2)" "unprognostic (2.99e-1)" "unprognostic (6.22e-2)" "unprognostic (2.35e-2)" TBC1D15 "DKFZp761D0223, FLJ12085" ENSG00000121749 "TBC1 domain family member 15" Q8TC07 12 71839707-71927248 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 485.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Kidney - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013388, HPA015592" Supported Supported Mitochondria,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 22 "Mitochondria, Cytosol" "HPA013388: , HPA015592: " "unprognostic (8.01e-3)" "unprognostic (7.70e-2)" "unprognostic (9.29e-2)" "unprognostic (3.74e-1)" "unprognostic (1.82e-1)" "unprognostic (3.82e-3)" "unprognostic (2.34e-1)" "unprognostic (6.48e-2)" "unprognostic (1.10e-1)" "unprognostic (2.97e-3)" "potential prognostic favorable (1.67e-9)" "unprognostic (2.10e-3)" "unprognostic (2.06e-1)" "unprognostic (1.80e-2)" "unprognostic (3.01e-2)" "unprognostic (2.27e-1)" "unprognostic (2.38e-1)" "unprognostic (3.00e-1)" "unprognostic (4.01e-2)" "unprognostic (2.87e-2)" "unprognostic (8.76e-3)" "unprognostic (2.41e-2)" "unprognostic (1.60e-3)" "unprognostic (4.05e-1)" "unprognostic (1.17e-2)" "unprognostic (2.21e-1)" "unprognostic (2.88e-1)" "unprognostic (3.73e-1)" "unprognostic (2.04e-2)" "unprognostic (1.99e-2)" "unprognostic (2.10e-1)" TBC1D16 "FLJ20748, MGC25062" ENSG00000167291 "TBC1 domain family member 16" Q8TBP0 17 79932343-80035872 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Kupffer cells: 263.4;Melanocytes: 190.2;Retinal horizontal cells: 336.6" "Cell type enhanced" "Detected in all" "fibroblast: 121.6" "Cancer enriched" "Detected in all" 5 "Skin Cutaneous Melanoma (TCGA): 127.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.9;non-classical monocyte: 2.3" "Lineage enhanced" "Detected in single" "monocytes: 2.3" "Cancer enriched" "Detected in all" 4 "skin cancer: 234.2" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024482, HPA065839" Approved Approved "Intermediate filaments" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 72: Kidney - Transmembrane transport" "Cluster 38: Sub-cortical - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 2 "Intermediate filaments" "HPA024482: , HPA065839: " "unprognostic (6.91e-2)" "unprognostic (1.88e-1)" "unprognostic (4.30e-3)" "unprognostic (1.53e-2)" "unprognostic (1.02e-1)" "unprognostic (6.56e-2)" "unprognostic (1.50e-3)" "unprognostic (5.69e-2)" "unprognostic (1.09e-1)" "unprognostic (7.38e-2)" "unprognostic (3.81e-3)" "unprognostic (7.14e-3)" "unprognostic (8.07e-2)" "unprognostic (4.08e-3)" "unprognostic (7.39e-3)" "unprognostic (2.51e-1)" "potential prognostic unfavorable (3.45e-4)" "unprognostic (2.16e-1)" "unprognostic (1.27e-1)" "unprognostic (4.17e-2)" "unprognostic (1.13e-1)" "unprognostic (1.60e-1)" "unprognostic (2.88e-1)" "unprognostic (3.76e-1)" "unprognostic (1.92e-3)" "potential prognostic favorable (3.84e-4)" "unprognostic (7.95e-2)" "unprognostic (8.47e-2)" "unprognostic (3.59e-1)" "unprognostic (1.15e-2)" "unprognostic (1.93e-2)" TBC1D17 FLJ12168 ENSG00000104946 "TBC1 domain family member 17" Q9HA65 19 49877666-49888750 "Predicted intracellular proteins" "Autophagy, Protein transport, Transport" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 132.3" "Cell type enhanced" "Detected in many" "Oocytes: 340.8;Syncytiotrophoblasts: 88.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068119 Uncertain NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 24: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 4: Non-specific - Transcription" "Cluster 41: Oocytes - Oogenesis" 11 "HPA068119: " "unprognostic (1.86e-2)" "unprognostic (3.69e-2)" "unprognostic (1.98e-1)" "unprognostic (5.04e-2)" "unprognostic (2.88e-2)" "potential prognostic unfavorable (1.48e-4)" "unprognostic (1.23e-1)" "unprognostic (1.21e-1)" "unprognostic (2.79e-2)" "unprognostic (3.72e-1)" "potential prognostic favorable (3.14e-4)" "unprognostic (6.09e-3)" "potential prognostic favorable (6.93e-4)" "unprognostic (9.72e-2)" "unprognostic (3.68e-2)" "unprognostic (5.10e-2)" "unprognostic (4.00e-2)" "unprognostic (2.76e-1)" "unprognostic (3.30e-1)" "unprognostic (9.93e-2)" "unprognostic (2.79e-2)" "unprognostic (2.05e-3)" "unprognostic (8.02e-2)" "unprognostic (8.32e-2)" "unprognostic (1.56e-1)" "unprognostic (4.42e-1)" "unprognostic (8.01e-2)" "unprognostic (7.82e-2)" "unprognostic (9.69e-3)" "unprognostic (1.48e-1)" "unprognostic (2.06e-2)" TBC1D19 FLJ11082 ENSG00000109680 "TBC1 domain family member 19" Q8N5T2 4 26576437-26756223 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 274.2;Ependymal cells: 225.6;Proximal tubule cells: 273.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039592 Approved Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 45: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 88: Proximal tubular cells - Transmembrane transport" 3 "Nuclear membrane" Nucleoplasm "HPA039592: " "unprognostic (3.71e-2)" "unprognostic (2.84e-3)" "unprognostic (2.61e-3)" "unprognostic (1.95e-1)" "unprognostic (6.23e-2)" "unprognostic (6.79e-2)" "unprognostic (2.10e-1)" "unprognostic (1.70e-2)" "unprognostic (1.37e-1)" "unprognostic (1.11e-2)" "validated prognostic favorable (3.67e-10)" "validated prognostic favorable (2.04e-6)" "unprognostic (1.25e-2)" "unprognostic (3.56e-2)" "unprognostic (2.90e-2)" "unprognostic (1.31e-1)" "unprognostic (2.09e-1)" "unprognostic (3.31e-3)" "unprognostic (9.95e-2)" "unprognostic (1.89e-1)" "unprognostic (1.45e-3)" "unprognostic (3.50e-2)" "unprognostic (2.11e-2)" "unprognostic (7.94e-2)" "unprognostic (9.79e-2)" "unprognostic (3.10e-1)" "unprognostic (1.78e-2)" "unprognostic (6.69e-3)" "unprognostic (1.19e-1)" "unprognostic (1.61e-2)" "unprognostic (3.12e-1)" TBC1D2 "Armus, PARIS1, TBC1D2A" ENSG00000095383 "TBC1 domain family member 2" Q9BYX2 9 98199011-98255649 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 341.4;monocytes: 136.1;Neutrophils: 116.7;Papillary tip epithelial cells: 112.5;Prostatic hillock cells: 113.4;Respiratory basal cells: 122.7" "Cell type enhanced" "Detected in all" "oligodendrocyte: 71.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 27.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose visceral - Macrophages, Colon - Macrophages, Skin - Keratinocyte (other)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA030871, HPA076521" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA Yes "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 2 "Nucleoplasm, Plasma membrane, Cytosol" "HPA030871: , HPA076521: " "unprognostic (3.28e-1)" "unprognostic (1.81e-1)" "unprognostic (5.01e-2)" "unprognostic (1.16e-1)" "unprognostic (2.43e-1)" "unprognostic (7.14e-2)" "unprognostic (1.10e-3)" "unprognostic (1.61e-1)" "potential prognostic unfavorable (6.09e-4)" "unprognostic (1.06e-1)" "potential prognostic unfavorable (8.60e-4)" "unprognostic (4.03e-2)" "unprognostic (1.04e-1)" "unprognostic (1.21e-1)" "unprognostic (3.71e-1)" "unprognostic (1.74e-1)" "unprognostic (7.93e-2)" "unprognostic (3.10e-1)" "unprognostic (1.84e-1)" "unprognostic (9.16e-3)" "unprognostic (2.40e-3)" "unprognostic (1.96e-2)" "unprognostic (1.82e-2)" "unprognostic (2.79e-1)" "unprognostic (1.34e-1)" "unprognostic (2.13e-1)" "unprognostic (1.16e-1)" "unprognostic (3.44e-1)" "potential prognostic unfavorable (6.19e-4)" "unprognostic (1.23e-2)" "unprognostic (3.30e-2)" TBC1D20 "C20orf140, dJ852M4.2" ENSG00000125875 "TBC1 domain family member 20" Q96BZ9 20 423596-462566 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Host-virus interaction" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 222.8;Late spermatids: 227.7;Platelets: 317.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043613 Approved NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 74: Non-specific - Signal transduction" "Cluster 19: Astrocytes - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 47: Platelets - Hemostasis" 5 "HPA043613: " "unprognostic (6.31e-2)" "potential prognostic unfavorable (6.20e-4)" "unprognostic (7.66e-3)" "unprognostic (3.39e-3)" "unprognostic (1.97e-1)" "unprognostic (1.57e-1)" "unprognostic (2.43e-1)" "unprognostic (4.71e-3)" "unprognostic (1.31e-1)" "unprognostic (1.40e-1)" "unprognostic (2.64e-3)" "unprognostic (6.34e-2)" "unprognostic (1.30e-1)" "unprognostic (2.47e-3)" "unprognostic (2.73e-2)" "unprognostic (1.69e-1)" "unprognostic (1.55e-1)" "unprognostic (5.04e-3)" "unprognostic (4.49e-2)" "unprognostic (5.09e-3)" "unprognostic (2.54e-1)" "unprognostic (8.29e-2)" "unprognostic (9.37e-2)" "unprognostic (1.61e-1)" "unprognostic (7.46e-3)" "unprognostic (1.16e-1)" "unprognostic (7.84e-2)" "unprognostic (5.78e-2)" "unprognostic (4.64e-1)" "unprognostic (9.13e-2)" "unprognostic (1.03e-1)" TBC1D21 "MGC34741, MgcRabGAP" ENSG00000167139 "TBC1 domain family member 21" Q8IYX1 15 73873564-73889214 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 465 "testis: 46.4" "Group enriched" "Detected in some" 5 "Early spermatids: 475.1;Late spermatids: 1706.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA043319 Enhanced Approved "Calyx,Mid piece" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 70: DU4475 - Unknown function" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 16 "Calyx, Mid piece" "HPA043319: " TBC1D22A C22orf4 ENSG00000054611 "TBC1 domain family member 22A" Q8WUA7 22 46762617-47175699 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglia: 865.1" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 1104.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001173, HPA078026" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 66: Non-specific - Mitochondria" "Cluster 82: Dendritic cells - Antigen presentation" 2 "Golgi apparatus" "Nucleoplasm, Vesicles" "HPA001173: , HPA078026: " "unprognostic (2.46e-2)" "unprognostic (8.86e-2)" "unprognostic (3.93e-1)" "unprognostic (5.28e-3)" "unprognostic (2.10e-1)" "unprognostic (1.57e-1)" "unprognostic (1.16e-1)" "unprognostic (6.59e-2)" "unprognostic (2.62e-1)" "unprognostic (2.47e-2)" "unprognostic (1.25e-2)" "unprognostic (1.29e-1)" "potential prognostic favorable (1.39e-4)" "unprognostic (1.45e-3)" "unprognostic (1.61e-3)" "unprognostic (1.24e-1)" "unprognostic (3.47e-2)" "unprognostic (2.16e-1)" "unprognostic (1.69e-1)" "unprognostic (3.16e-3)" "unprognostic (1.33e-1)" "unprognostic (2.01e-1)" "unprognostic (1.35e-2)" "unprognostic (1.30e-1)" "unprognostic (1.34e-2)" "unprognostic (1.03e-1)" "unprognostic (2.38e-2)" "unprognostic (1.31e-1)" "unprognostic (1.30e-1)" "unprognostic (1.51e-2)" "unprognostic (1.42e-1)" TBC1D22B "C6orf197, dJ744I24.2, FLJ20337" ENSG00000065491 "TBC1 domain family member 22B" Q9NU19 6 37257772-37332970 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027908, HPA027909, HPA027910" Uncertain Uncertain Nucleoplasm,Cytosol NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 55 "Nucleoplasm, Cytosol" "HPA027908: , HPA027909: , HPA027910: " "unprognostic (4.08e-1)" "unprognostic (5.71e-2)" "unprognostic (9.79e-2)" "unprognostic (5.20e-2)" "unprognostic (1.46e-1)" "unprognostic (3.96e-3)" "unprognostic (3.24e-1)" "unprognostic (1.35e-1)" "unprognostic (1.87e-1)" "unprognostic (4.01e-2)" "validated prognostic favorable (2.10e-6)" "validated prognostic favorable (9.77e-8)" "unprognostic (1.15e-2)" "unprognostic (2.24e-2)" "unprognostic (2.06e-2)" "unprognostic (4.88e-1)" "unprognostic (7.88e-2)" "unprognostic (2.85e-1)" "unprognostic (1.76e-1)" "unprognostic (5.39e-2)" "unprognostic (2.44e-1)" "unprognostic (3.97e-2)" "unprognostic (4.79e-3)" "unprognostic (8.92e-2)" "unprognostic (1.26e-3)" "unprognostic (2.28e-1)" "unprognostic (1.24e-1)" "unprognostic (5.42e-2)" "unprognostic (2.13e-1)" "unprognostic (8.16e-2)" "unprognostic (3.69e-2)" TBC1D23 FLJ11046 ENSG00000036054 "TBC1 domain family member 23" Q9NUY8 3 100260992-100325251 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 297.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038151, HPA038152" Approved Enhanced "Golgi apparatus" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 76: Non-specific - Metabolism" "Cluster 55: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 10 "Golgi apparatus" "HPA038151: , HPA038152: " "unprognostic (1.71e-1)" "unprognostic (4.05e-3)" "unprognostic (4.06e-2)" "unprognostic (1.69e-2)" "unprognostic (1.35e-1)" "unprognostic (1.00e-1)" "unprognostic (2.88e-1)" "unprognostic (2.78e-1)" "unprognostic (4.62e-2)" "potential prognostic unfavorable (5.12e-4)" "potential prognostic favorable (1.27e-7)" "unprognostic (3.04e-1)" "unprognostic (3.02e-1)" "unprognostic (1.36e-1)" "unprognostic (1.07e-1)" "unprognostic (2.73e-1)" "unprognostic (2.32e-3)" "unprognostic (5.72e-3)" "unprognostic (3.06e-1)" "unprognostic (3.69e-2)" "potential prognostic unfavorable (1.21e-4)" "unprognostic (1.43e-2)" "potential prognostic unfavorable (4.83e-4)" "unprognostic (3.50e-2)" "unprognostic (4.80e-3)" "unprognostic (2.63e-1)" "unprognostic (3.41e-2)" "unprognostic (2.50e-1)" "unprognostic (1.48e-1)" "unprognostic (5.18e-2)" "unprognostic (2.00e-1)" TBC1D24 "DFNA65, DFNB86, KIAA1171, TLDC6" ENSG00000162065 "TBC1 domain family member 24" Q9ULP9 16 2475051-2509560 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Deafness, Disease variant, Epilepsy, Intellectual disability, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 15.5" "Cell type enhanced" "Detected in many" "Astrocytes: 17.2;Brain excitatory neurons: 38.6;Brain inhibitory neurons: 34.4;Distal convoluted tubule cells: 16.4;Oligodendrocyte progenitor cells: 32.6;Oligodendrocytes: 12.0;Other brain neurons: 34.3;Renal collecting duct intercalated cells: 11.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 17.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044712, HPA068080" Uncertain Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 70: Non-specific - Protein processing" "Cluster 14: Neurons - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 1 "Plasma membrane, Cell Junctions" "HPA044712: , HPA068080: " "unprognostic (6.07e-2)" "unprognostic (1.89e-2)" "unprognostic (1.56e-1)" "unprognostic (9.20e-2)" "unprognostic (2.03e-1)" "unprognostic (5.66e-2)" "unprognostic (3.18e-1)" "unprognostic (4.48e-3)" "unprognostic (3.78e-2)" "unprognostic (7.09e-2)" "unprognostic (3.17e-3)" "unprognostic (5.80e-2)" "unprognostic (1.80e-1)" "unprognostic (2.18e-1)" "potential prognostic favorable (2.93e-4)" "unprognostic (5.71e-2)" "unprognostic (2.55e-1)" "potential prognostic unfavorable (2.82e-4)" "unprognostic (6.29e-3)" "unprognostic (5.74e-2)" "unprognostic (8.89e-2)" "unprognostic (1.19e-1)" "unprognostic (2.02e-1)" "unprognostic (8.47e-2)" "unprognostic (1.55e-2)" "unprognostic (1.09e-2)" "unprognostic (2.57e-1)" "unprognostic (1.18e-2)" "unprognostic (2.66e-1)" "unprognostic (2.76e-3)" "unprognostic (1.52e-1)" TBC1D25 OATL1 ENSG00000068354 "TBC1 domain family member 25" Q3MII6 X 48539714-48562609 "Predicted intracellular proteins" Autophagy "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 61.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029197 Approved Approved NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 19 "HPA029197: " "unprognostic (2.87e-1)" "unprognostic (1.52e-2)" "unprognostic (4.45e-1)" "unprognostic (2.50e-1)" "unprognostic (9.97e-2)" "unprognostic (1.10e-1)" "unprognostic (1.01e-1)" "unprognostic (3.22e-1)" "unprognostic (2.53e-2)" "unprognostic (2.97e-3)" "potential prognostic favorable (5.75e-4)" "unprognostic (1.67e-1)" "unprognostic (4.61e-1)" "unprognostic (1.56e-2)" "unprognostic (1.86e-1)" "unprognostic (1.93e-1)" "unprognostic (1.36e-1)" "unprognostic (1.43e-1)" "unprognostic (1.17e-2)" "unprognostic (4.99e-2)" "unprognostic (1.86e-1)" "unprognostic (8.27e-2)" "unprognostic (9.43e-2)" "unprognostic (1.77e-1)" "unprognostic (1.58e-1)" "unprognostic (3.17e-2)" "unprognostic (1.52e-1)" "unprognostic (1.03e-2)" "unprognostic (3.81e-2)" "unprognostic (5.22e-2)" "unprognostic (8.24e-2)" TBC1D26 MGC51025 ENSG00000214946 "TBC1 domain family member 26" 17 15732247-15746162 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "testis: 15.9" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 6.6;Brain inhibitory neurons: 8.1;Early spermatids: 2.3;Late primary spermatocytes: 1.5;Oligodendrocytes: 1.1;Other brain neurons: 1.1" "Cell type enhanced" "Detected in many" "hippocampal dentate gyrus: 17.7;medium spiny neuron: 19.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" NA NA "Cluster 67: Testis - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Neurons - Synaptic function & neurogenesis" TBC1D28 FLJ40244 ENSG00000189375 "TBC1 domain family member 28" Q2M2D7 17 18634247-18644427 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 55 "testis: 18.3" "Cell type enhanced" "Detected in some" "Early spermatids: 97.0;Late primary spermatocytes: 31.5;Late spermatids: 19.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" HPA050044 Approved Nucleoplasm,Vesicles NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 29: Forebrain - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" Vesicles Nucleoplasm "HPA050044: " TBC1D2B KIAA1055 ENSG00000167202 "TBC1 domain family member 2B" Q9UPU7 15 77984036-78077724 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 202.9;Mesothelial cells: 183.9;Neutrophil progenitors: 180.3;Tuft cells: 242.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Fibroblasts_1, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041833, HPA048174, HPA052663" Approved Enhanced Cytosol NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 75: Ovary - Mixed function" "Cluster 44: Non-specific - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 89: Adipocytes - Lipid metabolism" 9 Cytosol "HPA041833: , HPA048174: , HPA052663: " "unprognostic (5.40e-2)" "unprognostic (1.21e-1)" "potential prognostic favorable (5.26e-5)" "unprognostic (7.90e-3)" "unprognostic (2.00e-1)" "unprognostic (1.51e-1)" "unprognostic (2.87e-1)" "unprognostic (3.48e-2)" "unprognostic (4.08e-2)" "unprognostic (6.78e-2)" "potential prognostic favorable (3.89e-5)" "unprognostic (1.67e-2)" "unprognostic (5.73e-2)" "unprognostic (2.14e-1)" "unprognostic (5.09e-3)" "unprognostic (1.59e-1)" "unprognostic (6.97e-2)" "unprognostic (2.83e-2)" "unprognostic (4.37e-2)" "potential prognostic unfavorable (7.83e-4)" "unprognostic (4.79e-1)" "unprognostic (2.25e-1)" "unprognostic (1.68e-2)" "unprognostic (4.27e-1)" "unprognostic (3.15e-2)" "unprognostic (3.61e-2)" "unprognostic (1.58e-1)" "unprognostic (9.34e-2)" "unprognostic (9.98e-2)" "unprognostic (2.04e-2)" "unprognostic (1.91e-2)" TBC1D3 "DKFZp434P2235, PRC17, TBC1D3A" ENSG00000274611 "TBC1 domain family member 3" Q8IZP1 17 38181659-38192555 "Predicted membrane proteins" "GTPase activation" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 11.7" "Cell type enriched" "Detected in some" 4 "Epididymal clear cells: 6.1" "Not detected" "Not detected" "Region enriched" "Detected in single" 6 "cerebral cortex: 5.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "pancreatic cancer: 2.4" "HPA046969, HPA047745, HPA052553" Approved Uncertain Vesicles NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 1: Neuronal - Visual perception" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" 2 Vesicles "HPA046969: , HPA047745: , HPA052553: " "unprognostic (2.14e-1)" "unprognostic (4.77e-1)" "unprognostic (4.61e-1)" "unprognostic (4.76e-1)" TBC1D30 KIAA0984 ENSG00000111490 "TBC1 domain family member 30" Q9Y2I9 12 64759484-64881033 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 10.1" "Cell type enhanced" "Detected in some" "Astrocytes: 20.3;Bergmann glia: 18.3;Brain excitatory neurons: 44.9;Brain inhibitory neurons: 50.6;Choroid plexus epithelial cells: 140.8;Distal convoluted tubule cells: 30.8;Ependymal cells: 18.8;Loop of henle epithelial cells: 29.2;Microglia: 28.3;Other brain neurons: 35.4;Papillary tip epithelial cells: 27.4;Renal collecting duct intercalated cells: 28.3;Renal collecting duct principal cells: 49.5;Renal connecting tubule cells: 44.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Endothelial cells, Spleen - Macrophages, Stomach - Chief cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039772, HPA040043" Approved Supported "Plasma membrane,Mid piece,Principal piece" NA NA "Cluster 70: Non-specific - Protein processing" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 1 "Plasma membrane" "Mid piece, Principal piece" "HPA039772: , HPA040043: " "unprognostic (1.75e-1)" "unprognostic (1.80e-2)" "unprognostic (3.01e-1)" "potential prognostic favorable (3.68e-4)" "unprognostic (2.99e-2)" "unprognostic (3.35e-1)" "potential prognostic favorable (2.10e-5)" "unprognostic (9.05e-2)" "unprognostic (4.97e-2)" "unprognostic (2.19e-2)" "unprognostic (2.65e-3)" "unprognostic (2.42e-2)" "unprognostic (1.58e-3)" "unprognostic (1.85e-1)" "unprognostic (1.59e-1)" "unprognostic (4.02e-2)" "unprognostic (4.41e-1)" "unprognostic (1.42e-1)" "unprognostic (1.34e-1)" "unprognostic (2.45e-1)" "unprognostic (3.01e-2)" "unprognostic (6.15e-2)" "unprognostic (6.56e-2)" "unprognostic (1.17e-2)" "unprognostic (4.92e-2)" TBC1D31 "Gm85, MGC21654, WDR67" ENSG00000156787 "TBC1 domain family member 31" Q96DN5 8 123041968-123152153 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 93.8;Innate lymphoid cells: 65.8;Lactotrophs: 67.9;NK-cells: 93.6;Thyrotrophs: 99.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023710 Approved Supported "Centrosome,Basal body" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 15: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 4 "Centrosome, Basal body" "HPA023710: " "unprognostic (8.93e-3)" "unprognostic (2.56e-2)" "unprognostic (1.31e-1)" "unprognostic (9.42e-2)" "unprognostic (1.29e-1)" "unprognostic (1.00e-1)" "unprognostic (1.22e-2)" "unprognostic (1.80e-1)" "unprognostic (2.47e-3)" "unprognostic (2.81e-2)" "unprognostic (5.28e-2)" "unprognostic (3.33e-2)" "unprognostic (3.82e-2)" "potential prognostic unfavorable (7.41e-5)" "unprognostic (1.84e-2)" "unprognostic (3.21e-1)" "unprognostic (3.61e-3)" "unprognostic (1.87e-1)" "unprognostic (5.95e-2)" "unprognostic (2.05e-1)" "unprognostic (3.51e-3)" "unprognostic (2.23e-3)" "unprognostic (2.51e-2)" "unprognostic (1.63e-2)" "unprognostic (1.54e-1)" "unprognostic (2.22e-2)" "unprognostic (1.64e-1)" "unprognostic (2.04e-2)" "unprognostic (6.13e-2)" TBC1D32 "bA57L9.1, BROMI, C6orf170, C6orf171, dJ310J6.1, FLJ30899, FLJ34235" ENSG00000146350 "TBC1 domain family member 32" Q96NH3 6 121079494-121334745 "Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 6.9" "Cell type enhanced" "Detected in many" "Gonadotrophs: 321.2;Lactotrophs: 355.8;Rod photoreceptor cells: 614.9;Somatotrophs: 389.9;Thyrotrophs: 313.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013413 Uncertain Approved Vesicles,Mitochondria,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 42: Retina - Visual perception" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" 6 "Mitochondria, Cytosol" Vesicles "HPA013413: " "unprognostic (8.10e-3)" "unprognostic (8.83e-2)" "unprognostic (7.17e-2)" "unprognostic (1.31e-1)" "unprognostic (1.48e-1)" "unprognostic (4.84e-2)" "unprognostic (3.02e-2)" "unprognostic (2.86e-2)" "unprognostic (3.59e-2)" "unprognostic (2.31e-3)" "unprognostic (2.55e-2)" "unprognostic (1.52e-1)" "unprognostic (1.52e-1)" "unprognostic (8.29e-2)" TBC1D3B "PRC17, TBC1D3I" ENSG00000274808 "TBC1 domain family member 3B" A6NDS4 17 36165683-36176636 "Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 6 "Early spermatids: 14.9" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "HPA046969, HPA047745, HPA052553" Approved Uncertain Vesicles NA NA "Cluster 67: Testis - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" Vesicles "HPA046969: , HPA047745: , HPA052553: " "unprognostic (4.81e-3)" "unprognostic (3.41e-3)" "unprognostic (3.69e-1)" "unprognostic (3.04e-2)" "unprognostic (1.57e-1)" "potential prognostic unfavorable (2.04e-5)" "unprognostic (4.74e-1)" "unprognostic (1.66e-1)" "unprognostic (1.37e-1)" "unprognostic (1.03e-1)" "unprognostic (3.77e-1)" "unprognostic (9.25e-3)" "unprognostic (2.70e-2)" TBC1D3C MGC44903 ENSG00000278299 "TBC1 domain family member 3C" Q6IPX1 17 38057693-38068634 "Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in single" 13 "Early spermatids: 2.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "HPA046969, HPA047745, HPA052553" Approved Uncertain Vesicles NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 48: Non-specific - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" Vesicles "HPA046969: , HPA047745: , HPA052553: " "unprognostic (4.68e-1)" "unprognostic (5.90e-1)" "unprognostic (2.81e-1)" "unprognostic (2.76e-1)" "unprognostic (1.61e-1)" "unprognostic (8.76e-2)" "unprognostic (1.39e-1)" "unprognostic (5.45e-2)" "unprognostic (2.67e-1)" "unprognostic (4.84e-2)" "unprognostic (5.33e-2)" "unprognostic (5.93e-1)" "unprognostic (3.42e-1)" TBC1D3D ENSG00000274419 "TBC1 domain family member 3D" A0A087WVF3 17 38003976-38014908 "Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 6 "Epididymal basal cells: 1.2;Epididymal clear cells: 2.0;Epididymal efferent duct absorptive cells: 1.0;Epididymal principal cells: 1.2;Foveolar cells: 3.7;Myonuclei: 1.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "HPA046969, HPA047745, HPA052553" Approved Uncertain Vesicles NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 59: Leukemia - T-cell receptor" "Cluster 68: Foveolar cells - Mucosal defense" Vesicles "HPA046969: , HPA047745: , HPA052553: " "unprognostic (1.39e-1)" "unprognostic (3.33e-1)" "unprognostic (7.59e-2)" "unprognostic (8.31e-2)" "unprognostic (2.40e-1)" "potential prognostic unfavorable (1.36e-5)" "unprognostic (7.89e-2)" "unprognostic (1.96e-1)" "unprognostic (9.35e-2)" "unprognostic (3.98e-1)" "unprognostic (3.80e-1)" "unprognostic (8.99e-2)" TBC1D3E ENSG00000278599 "TBC1 domain family member 3E" A0A087X179 17 38127951-38138868 "Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "testis: 3.4" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046969, HPA047745, HPA052553" Approved Uncertain Vesicles NA NA "Cluster 67: Testis - Mixed function" "Cluster 1: Neuronal - Visual perception" Vesicles "HPA046969: , HPA047745: , HPA052553: " TBC1D3F ENSG00000275954 "TBC1 domain family member 3F" 17 36428618-36439566 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 10 "testis: 6.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" HPA046969 Uncertain Vesicles NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 53: Squamous epithelial cells - Keratinization" Vesicles "HPA046969: " "unprognostic (3.32e-1)" TBC1D3G ENSG00000260287 "TBC1 domain family member 3G" Q6DHY5 17 36323884-36334759 "Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "testis: 26.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046969, HPA047745, HPA052553" Supported Approved Vesicles NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 53: Squamous epithelial cells - Keratinization" 8 Vesicles "HPA046969: , HPA047745: , HPA052553: " "unprognostic (1.26e-1)" TBC1D3H ENSG00000274226 "TBC1 domain family member 3H" P0C7X1 17 36377531-36388435 "Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "brain: 1.7;testis: 4.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046969, HPA047745, HPA052553" Approved Approved Vesicles NA NA "Cluster 67: Testis - Mixed function" Vesicles "HPA046969: , HPA047745: , HPA052553: " TBC1D3I ENSG00000274933 "TBC1 domain family member 3I" A0A087WXS9 17 36253456-36264570 "Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 4 "testis: 6.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Testis - Late spermatids" "HPA046969, HPA047745, HPA052553" Approved Uncertain Vesicles NA NA "Cluster 67: Testis - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 56: Non-specific - Sensory perception" Vesicles "HPA046969: , HPA047745: , HPA052553: " TBC1D3K ENSG00000273513 "TBC1 domain family member 3K" A0A087X1G2 17 37924415-37935371 "Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "testis: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046969, HPA047745, HPA052553" Approved Uncertain Vesicles NA NA "Cluster 67: Testis - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" Vesicles "HPA046969: , HPA047745: , HPA052553: " TBC1D3L ENSG00000274512 "TBC1 domain family member 3L" B9A6J9 17 37978155-37989060 "Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in single" "Papillary tip epithelial cells: 1.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "HPA046969, HPA047745, HPA052553" Approved Uncertain Vesicles NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 105: Non-specific - Mixed function" Vesicles "HPA046969: , HPA047745: , HPA052553: " "unprognostic (9.71e-2)" "unprognostic (5.49e-2)" "unprognostic (3.31e-2)" "unprognostic (1.56e-1)" "unprognostic (3.14e-1)" "unprognostic (2.13e-1)" "unprognostic (6.09e-2)" "unprognostic (4.52e-1)" "potential prognostic unfavorable (3.11e-6)" "unprognostic (2.73e-1)" "unprognostic (4.66e-2)" "unprognostic (1.10e-2)" "unprognostic (5.32e-2)" "unprognostic (1.51e-1)" "unprognostic (9.51e-2)" "unprognostic (4.32e-2)" "unprognostic (2.26e-1)" "unprognostic (2.93e-1)" "unprognostic (5.13e-2)" "unprognostic (2.84e-1)" "unprognostic (1.00e-1)" "unprognostic (9.89e-2)" "unprognostic (1.61e-1)" "unprognostic (1.11e-1)" "unprognostic (3.17e-1)" "unprognostic (3.45e-1)" TBC1D4 "AS160, DKFZp779C0666, KIAA0603" ENSG00000136111 "TBC1 domain family member 4" O60343 13 75283503-75482169 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "GTPase activation" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 77.5" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 1167.5;Cardiomyocytes: 601.2;Loop of henle epithelial cells: 544.5;Microglia: 456.5;Myonuclei: 961.0;Pituicytes/FSCs: 540.2;Renal collecting duct intercalated cells: 792.9;Thymic myoid cells: 509.9" "Cell type enhanced" "Detected in all" "endothelial cell: 1520.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 25.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Spleen - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040145, HPA059885" Approved Enhanced Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 47: Endothelial cells - Vasculature" "Cluster 19: Non-specific - Unknown function" "Cluster 104: Brain endothelial cells - Blood brain barrier" 39 Cytosol "HPA040145: , HPA059885: " "potential prognostic favorable (8.58e-5)" "unprognostic (8.81e-3)" "unprognostic (3.26e-2)" "unprognostic (3.02e-1)" "unprognostic (2.94e-1)" "unprognostic (8.42e-3)" "unprognostic (1.10e-1)" "unprognostic (7.15e-2)" "unprognostic (1.90e-3)" "unprognostic (1.21e-2)" "potential prognostic favorable (7.05e-8)" "unprognostic (3.45e-3)" "potential prognostic favorable (5.92e-4)" "unprognostic (4.89e-3)" "unprognostic (1.98e-1)" "unprognostic (1.93e-1)" "unprognostic (1.96e-1)" "unprognostic (8.79e-2)" "unprognostic (8.12e-3)" "unprognostic (5.02e-2)" "unprognostic (3.00e-1)" "unprognostic (1.20e-1)" "unprognostic (3.65e-1)" "unprognostic (2.89e-1)" "unprognostic (2.22e-2)" "unprognostic (3.95e-3)" "unprognostic (2.13e-1)" "unprognostic (3.76e-2)" "unprognostic (4.32e-2)" "unprognostic (3.59e-2)" "unprognostic (1.02e-2)" TBC1D5 KIAA0210 ENSG00000131374 "TBC1 domain family member 5" Q92609 3 17157162-18444817 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Autophagy, Protein transport, Transport" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035125, HPA035126" Uncertain Supported "Golgi apparatus,Vesicles" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 37 Vesicles "Golgi apparatus" "HPA035125: , HPA035126: " "unprognostic (1.43e-1)" "unprognostic (2.10e-1)" "unprognostic (6.91e-2)" "unprognostic (4.26e-2)" "unprognostic (3.88e-1)" "unprognostic (4.14e-2)" "unprognostic (1.63e-1)" "unprognostic (5.60e-2)" "unprognostic (1.89e-2)" "unprognostic (2.87e-2)" "validated prognostic favorable (7.22e-6)" "validated prognostic favorable (6.01e-4)" "unprognostic (1.40e-2)" "unprognostic (2.14e-2)" "unprognostic (5.97e-2)" "unprognostic (4.86e-1)" "unprognostic (2.70e-2)" "unprognostic (6.01e-2)" "unprognostic (1.82e-1)" "unprognostic (5.94e-2)" "potential prognostic unfavorable (9.22e-4)" "unprognostic (2.67e-2)" "unprognostic (2.29e-1)" "unprognostic (2.60e-1)" "potential prognostic favorable (6.21e-4)" "unprognostic (6.38e-2)" "unprognostic (9.63e-2)" "unprognostic (8.95e-2)" "unprognostic (1.51e-1)" "unprognostic (2.24e-2)" "unprognostic (2.06e-1)" TBC1D7 "dJ257A7.3, FLJ32666" ENSG00000145979 "TBC1 domain family member 7" Q9P0N9 6 13266542-13328583 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 163.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 165.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "skin cancer: 204.0" "Heart muscle - Cardiomyocytes, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034748 Approved NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 52: Non-specific - Cellular respiration" "Cluster 12: Non-specific - Vasculature" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 40 "HPA034748: " "unprognostic (6.89e-3)" "unprognostic (5.81e-3)" "unprognostic (3.53e-1)" "unprognostic (2.71e-1)" "unprognostic (4.76e-1)" "unprognostic (3.25e-2)" "unprognostic (7.47e-2)" "potential prognostic favorable (5.04e-5)" "unprognostic (4.03e-2)" "unprognostic (1.14e-2)" "unprognostic (5.54e-3)" "unprognostic (3.19e-2)" "unprognostic (1.39e-1)" "validated prognostic unfavorable (3.76e-4)" "validated prognostic unfavorable (3.13e-4)" "unprognostic (1.98e-1)" "unprognostic (8.70e-2)" "unprognostic (1.89e-2)" "unprognostic (3.50e-1)" "potential prognostic favorable (7.87e-5)" "unprognostic (3.69e-2)" "unprognostic (1.18e-1)" "unprognostic (4.83e-2)" "unprognostic (5.08e-2)" "unprognostic (1.11e-1)" "unprognostic (6.63e-2)" "unprognostic (2.05e-1)" "unprognostic (1.20e-1)" "unprognostic (1.13e-1)" "unprognostic (6.13e-2)" "unprognostic (2.93e-2)" TBC1D8 "AD3, GRAMD8, HBLP1, VRP" ENSG00000204634 "TBC1 domain family member 8" O95759 2 101007228-101252866 "Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Breast lactating cells: 1029.2;Endometrial ciliated cells: 526.6;Endometrial glandular cells: 585.1;Myonuclei: 812.7;Neutrophils: 694.7;Prostatic glandular cells: 612.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 30.1;non-classical monocyte: 38.3" "Lineage enriched" "Detected in many" 5 "monocytes: 38.3" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Kidney - Endothelial cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015211, HPA074921" Uncertain Approved "Nucleoplasm,Plasma membrane,Centrosome" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 49: Non-specific - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 82: Dendritic cells - Antigen presentation" 7 "Nucleoplasm, Plasma membrane" Centrosome "CAB015211: , HPA074921: " "unprognostic (3.45e-1)" "unprognostic (3.17e-1)" "unprognostic (5.38e-2)" "unprognostic (1.04e-1)" "unprognostic (4.58e-2)" "unprognostic (9.05e-3)" "unprognostic (1.22e-1)" "unprognostic (5.15e-3)" "unprognostic (2.88e-2)" "unprognostic (4.77e-3)" "potential prognostic favorable (6.42e-4)" "unprognostic (2.48e-3)" "unprognostic (4.18e-2)" "unprognostic (6.15e-3)" "unprognostic (4.41e-2)" "unprognostic (2.09e-1)" "unprognostic (5.58e-2)" "unprognostic (3.24e-1)" "unprognostic (1.03e-1)" "unprognostic (1.54e-1)" "unprognostic (7.97e-2)" "unprognostic (6.83e-2)" "potential prognostic unfavorable (8.15e-5)" "unprognostic (2.32e-1)" "unprognostic (2.05e-1)" "unprognostic (1.80e-1)" "unprognostic (3.27e-1)" "unprognostic (7.75e-2)" "unprognostic (1.78e-1)" "unprognostic (3.51e-2)" "unprognostic (1.47e-1)" TBC1D8B "FLJ20298, GRAMD8B, RP11-321G1.1" ENSG00000133138 "TBC1 domain family member 8B" Q0IIM8 X 106802673-106876150 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "GTPase activation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 127.5;Choroid plexus epithelial cells: 130.0;Corticotrophs: 148.4;Gonadotrophs: 117.3;Lactotrophs: 81.4;Sertoli cells: 128.3;Somatotrophs: 101.8" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 99.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells, Skin - Endothelial cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023883, HPA027527" Enhanced Approved Cytosol NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 9: Non-specific - Receptor signaling" "Cluster 56: Non-specific - Sensory perception" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" Cytosol "HPA023883: , HPA027527: " "unprognostic (3.51e-1)" "unprognostic (4.69e-2)" "unprognostic (3.46e-1)" "unprognostic (4.24e-3)" "unprognostic (1.02e-2)" "unprognostic (1.75e-1)" "unprognostic (1.06e-1)" "unprognostic (3.27e-2)" "unprognostic (6.46e-2)" "unprognostic (1.67e-3)" "unprognostic (2.52e-3)" "unprognostic (1.62e-1)" "unprognostic (9.70e-2)" "unprognostic (9.42e-2)" "unprognostic (2.50e-1)" "unprognostic (2.01e-1)" "unprognostic (4.35e-3)" "unprognostic (6.01e-2)" "unprognostic (2.16e-1)" "unprognostic (2.71e-1)" "unprognostic (3.16e-1)" "unprognostic (1.69e-1)" "unprognostic (6.80e-3)" "unprognostic (1.12e-1)" "unprognostic (7.38e-2)" "unprognostic (2.89e-1)" "unprognostic (1.00e-1)" "unprognostic (1.68e-1)" "unprognostic (1.35e-1)" "unprognostic (3.97e-3)" "unprognostic (4.68e-2)" TBC1D9 "GRAMD9, KIAA0882, MDR1" ENSG00000109436 "TBC1 domain family member 9" Q6ZT07 4 140620782-140756385 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 489.9;Endometrial luminal cells: 255.9;Microglia: 279.9;Plasma cells: 288.9;Renal connecting tubule cells: 358.8" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 369.8" "Group enriched" "Detected in all" 5 "Breast Invasive Carcinoma (TCGA): 133.4;Kidney Chromophobe (TCGA): 33.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 5.9" "Group enriched" "Detected in many" 37 "B-cells: 5.9;dendritic cells: 3.2;monocytes: 1.7" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Skeletal muscle - Endothelial cells, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000262, HPA006503" Uncertain Approved Cytosol NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 13: Lung - Secretion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 82: Dendritic cells - Antigen presentation" 11 Cytosol "HPA000262: , HPA006503: " "unprognostic (2.67e-3)" "unprognostic (2.80e-1)" "unprognostic (1.33e-1)" "unprognostic (3.50e-2)" "unprognostic (2.02e-1)" "unprognostic (2.61e-1)" "unprognostic (1.49e-1)" "unprognostic (1.94e-3)" "unprognostic (1.36e-3)" "unprognostic (2.22e-1)" "potential prognostic favorable (2.16e-7)" "unprognostic (2.86e-3)" "unprognostic (2.86e-1)" "unprognostic (3.28e-2)" "unprognostic (2.13e-3)" "unprognostic (2.80e-2)" "unprognostic (1.86e-1)" "unprognostic (1.63e-1)" "unprognostic (2.92e-1)" "unprognostic (7.10e-2)" "unprognostic (3.66e-3)" "unprognostic (3.44e-3)" "unprognostic (3.26e-2)" "unprognostic (8.95e-2)" "unprognostic (4.78e-2)" "unprognostic (1.97e-2)" "unprognostic (2.08e-1)" "unprognostic (2.36e-2)" "unprognostic (1.17e-1)" "unprognostic (3.36e-1)" "unprognostic (2.10e-1)" TBC1D9B "GRAMD9B, KIAA0676" ENSG00000197226 "TBC1 domain family member 9B" Q66K14 5 179862066-179907897 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 30.5;Bergmann glia: 25.7;Brain excitatory neurons: 43.5;Brain inhibitory neurons: 30.3;Choroid plexus epithelial cells: 24.9;Distal convoluted tubule cells: 30.5;Loop of henle epithelial cells: 30.5;Microglia: 46.2;Oligodendrocyte progenitor cells: 25.9;Oligodendrocytes: 32.3;Other brain neurons: 31.3;Papillary tip epithelial cells: 28.8;Podocytes: 51.4;Proximal tubule cells: 34.1;Renal collecting duct intercalated cells: 25.6;Renal collecting duct principal cells: 34.0;Renal connecting tubule cells: 31.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038350 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Plasma membrane,Actin filaments" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 102: Non-specific - Mixed function" 3 "Plasma membrane" "Nucleoplasm, Nucleoli fibrillar center, Actin filaments" "HPA038350: " "unprognostic (2.87e-1)" "unprognostic (3.49e-2)" "unprognostic (1.29e-1)" "unprognostic (2.57e-1)" "unprognostic (5.34e-2)" "unprognostic (1.44e-2)" "unprognostic (2.87e-1)" "unprognostic (2.31e-2)" "unprognostic (1.11e-1)" "unprognostic (5.19e-2)" "potential prognostic favorable (4.08e-8)" "unprognostic (9.17e-2)" "unprognostic (3.57e-2)" "unprognostic (1.12e-1)" "unprognostic (9.88e-2)" "unprognostic (9.10e-2)" "unprognostic (1.49e-1)" "unprognostic (6.31e-3)" "unprognostic (1.33e-1)" "unprognostic (4.27e-2)" "unprognostic (1.42e-1)" "unprognostic (1.56e-1)" "unprognostic (2.76e-2)" "unprognostic (1.08e-1)" "unprognostic (1.07e-1)" "unprognostic (1.18e-1)" "unprognostic (9.50e-2)" "unprognostic (1.72e-1)" "unprognostic (1.93e-1)" "unprognostic (9.75e-3)" "unprognostic (2.89e-1)" TBCA ENSG00000171530 "Tubulin folding cofactor A" O75347 5 77691166-77868780 "Essential proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1090.7;Hepatocytes: 1393.6;Parietal cells: 1775.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036487 Approved Supported Nucleoli,Microtubules NA NA 5300000 "Cluster 13: Non-specific - Mitochondria" "Cluster 76: Non-specific - Metabolism" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 97: Non-specific - Cellular respiration" 9 Microtubules Nucleoli "HPA036487: " "unprognostic (6.12e-2)" "unprognostic (1.74e-2)" "unprognostic (2.00e-2)" "unprognostic (1.17e-1)" "unprognostic (2.34e-1)" "unprognostic (8.21e-2)" "unprognostic (2.08e-1)" "potential prognostic unfavorable (4.51e-4)" "potential prognostic unfavorable (5.76e-4)" "potential prognostic unfavorable (2.79e-5)" "potential prognostic favorable (4.54e-5)" "unprognostic (2.90e-1)" "unprognostic (5.60e-2)" "unprognostic (1.82e-2)" "unprognostic (8.89e-3)" "unprognostic (4.85e-3)" "unprognostic (1.90e-2)" "unprognostic (2.14e-1)" "unprognostic (1.35e-1)" "unprognostic (8.60e-2)" "unprognostic (5.23e-2)" "unprognostic (2.05e-1)" "potential prognostic unfavorable (7.35e-4)" "unprognostic (1.93e-1)" "unprognostic (2.27e-1)" "unprognostic (8.88e-2)" "unprognostic (1.45e-1)" "unprognostic (1.85e-3)" "unprognostic (9.22e-2)" "unprognostic (8.38e-2)" "unprognostic (5.93e-3)" TBCB "CG22, CKAP1, CKAPI" ENSG00000105254 "Tubulin folding cofactor B" Q99426 19 36114289-36125947 "Essential proteins, Metabolic proteins, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Chaperone, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 386.0" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 279.5;Late spermatids: 370.5;Oocytes: 589.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041428, HPA041722" Approved Supported Cytosol NA NA 430000 "Cluster 25: Non-specific - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 4: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 14 Cytosol "HPA041428: , HPA041722: " "unprognostic (2.50e-3)" "unprognostic (1.93e-2)" "unprognostic (3.85e-1)" "unprognostic (7.10e-2)" "unprognostic (1.50e-1)" "unprognostic (1.75e-1)" "unprognostic (1.62e-1)" "unprognostic (2.71e-1)" "unprognostic (1.27e-1)" "unprognostic (9.46e-2)" "unprognostic (5.29e-2)" "unprognostic (7.39e-2)" "unprognostic (2.39e-1)" "potential prognostic unfavorable (1.27e-4)" "unprognostic (2.02e-3)" "unprognostic (2.10e-1)" "unprognostic (2.52e-1)" "unprognostic (2.92e-1)" "unprognostic (3.83e-1)" "unprognostic (4.01e-1)" "unprognostic (1.57e-1)" "unprognostic (1.87e-3)" "unprognostic (3.19e-1)" "unprognostic (3.17e-2)" "unprognostic (3.66e-2)" "unprognostic (3.75e-2)" "unprognostic (1.09e-1)" "unprognostic (3.58e-2)" "unprognostic (5.44e-2)" "unprognostic (2.65e-1)" "unprognostic (1.49e-1)" TBCC CFC ENSG00000124659 "Tubulin folding cofactor C" Q15814 6 42744498-42746103 "Essential proteins, Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 74.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035073, HPA035074" Approved Supported Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 20: Non-specific - Transcription regulation" 4 Cytosol "HPA035073: , HPA035074: " "unprognostic (2.79e-1)" "unprognostic (3.32e-1)" "unprognostic (2.61e-1)" "unprognostic (2.51e-2)" "unprognostic (2.20e-1)" "unprognostic (2.07e-2)" "unprognostic (2.22e-1)" "unprognostic (2.01e-2)" "unprognostic (9.62e-2)" "unprognostic (1.22e-1)" "unprognostic (1.54e-3)" "unprognostic (5.41e-2)" "unprognostic (3.49e-2)" "unprognostic (1.02e-2)" "unprognostic (2.83e-2)" "unprognostic (2.55e-2)" "unprognostic (9.00e-2)" "unprognostic (7.50e-2)" "unprognostic (1.57e-1)" "unprognostic (6.12e-2)" "unprognostic (4.39e-1)" "unprognostic (9.00e-3)" "unprognostic (2.78e-1)" "unprognostic (3.21e-1)" "unprognostic (2.37e-2)" "unprognostic (2.41e-1)" "unprognostic (4.83e-1)" "unprognostic (2.95e-1)" "unprognostic (2.75e-1)" "unprognostic (3.09e-2)" "unprognostic (1.77e-1)" TBCCD1 FLJ10560 ENSG00000113838 "TBCC domain containing 1" Q9NVR7 3 186546067-186570543 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 58.9;Epididymal principal cells: 60.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 39: Testis - Nuclear processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 63: Non-specific - Protein processing" "Cluster 65: Non-specific - Cell growth & division" 9 "unprognostic (1.06e-1)" "unprognostic (1.93e-1)" "unprognostic (3.62e-2)" "unprognostic (7.14e-2)" "unprognostic (3.74e-1)" "unprognostic (3.48e-2)" "unprognostic (3.28e-2)" "unprognostic (2.43e-2)" "unprognostic (8.99e-2)" "unprognostic (7.61e-3)" "validated prognostic favorable (4.32e-4)" "validated prognostic favorable (3.50e-4)" "unprognostic (2.46e-1)" "unprognostic (7.88e-3)" "unprognostic (3.11e-2)" "potential prognostic unfavorable (1.31e-4)" "unprognostic (4.46e-2)" "unprognostic (4.20e-2)" "unprognostic (6.28e-3)" "unprognostic (8.11e-2)" "unprognostic (7.93e-2)" "unprognostic (3.16e-3)" "unprognostic (4.30e-3)" "unprognostic (1.51e-1)" "unprognostic (8.19e-2)" "unprognostic (4.41e-1)" "unprognostic (2.11e-2)" "unprognostic (2.61e-1)" "unprognostic (1.05e-1)" "unprognostic (7.09e-2)" "unprognostic (3.85e-1)" TBCD ENSG00000141556 "Tubulin folding cofactor D" Q9BTW9 17 82752042-82945914 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Chaperone, GTPase activation" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial luminal cells: 196.6;Thymocytes: 240.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045200 Approved NA NA 7000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 82: Salivary gland - Secretion" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 9 "HPA045200: " "unprognostic (3.52e-2)" "unprognostic (7.34e-2)" "unprognostic (1.04e-1)" "unprognostic (5.50e-2)" "unprognostic (1.75e-2)" "unprognostic (2.12e-1)" "unprognostic (2.94e-1)" "unprognostic (1.10e-2)" "unprognostic (3.16e-2)" "potential prognostic unfavorable (9.89e-4)" "potential prognostic favorable (2.74e-4)" "unprognostic (4.80e-2)" "unprognostic (2.41e-1)" "potential prognostic unfavorable (9.24e-4)" "unprognostic (5.53e-3)" "unprognostic (1.71e-3)" "unprognostic (1.50e-1)" "unprognostic (1.40e-1)" "unprognostic (4.72e-2)" "unprognostic (1.65e-2)" "potential prognostic favorable (1.31e-4)" "unprognostic (1.71e-1)" "unprognostic (1.20e-3)" "unprognostic (2.66e-1)" "unprognostic (3.06e-1)" "unprognostic (5.80e-3)" "unprognostic (1.26e-1)" "unprognostic (1.59e-1)" "unprognostic (6.67e-2)" "unprognostic (1.45e-1)" "unprognostic (3.22e-1)" TBCE "HRD, KCS, KCS1, pac2" ENSG00000284770 "Tubulin folding cofactor E" Q15813 1 235367360-235452443 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" Chaperone "Disease variant, Dwarfism, Intellectual disability, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 1.5;Bergmann glia: 2.4;Brain excitatory neurons: 2.8;Brain inhibitory neurons: 2.5;Choroid plexus epithelial cells: 1.1;Ependymal cells: 1.0;Microglia: 1.3;Oligodendrocyte progenitor cells: 1.9;Oligodendrocytes: 1.7;Other brain neurons: 2.3;Retinal ganglion cells: 3.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026552, HPA026557" Approved NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 45: Non-specific - Nuclear processes" "Cluster 22: Non-specific - Basic cellular functions" 2 "HPA026552: , HPA026557: " "unprognostic (4.28e-1)" "unprognostic (3.03e-1)" "unprognostic (2.20e-2)" "unprognostic (1.07e-1)" "unprognostic (1.75e-2)" "unprognostic (1.77e-1)" "unprognostic (3.46e-3)" "unprognostic (1.10e-2)" "unprognostic (1.01e-1)" "unprognostic (5.13e-3)" "unprognostic (1.19e-2)" "unprognostic (2.64e-2)" "unprognostic (1.07e-2)" "unprognostic (1.03e-1)" "unprognostic (6.47e-2)" "unprognostic (1.38e-1)" "unprognostic (1.92e-1)" "unprognostic (2.44e-2)" "unprognostic (1.42e-1)" "unprognostic (6.57e-2)" "unprognostic (1.32e-1)" "unprognostic (6.13e-2)" "unprognostic (2.33e-1)" "unprognostic (2.26e-1)" "unprognostic (1.00e-1)" "unprognostic (8.74e-2)" TBCE "HRD, KCS, KCS1, pac2" ENSG00000285053 "Tubulin folding cofactor E" Q15813 1 235328570-235448952 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" Chaperone "Disease variant, Dwarfism, Intellectual disability, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 22.6;Brain inhibitory neurons: 24.3;Myonuclei: 20.5;Other brain neurons: 23.3;Retinal ganglion cells: 54.1;Retinal horizontal cells: 24.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA026552, HPA026557" Approved NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 109: Neurons - Neuronal signaling" 2 "HPA026552: , HPA026557: " "unprognostic (2.66e-1)" "unprognostic (9.34e-2)" "unprognostic (1.53e-1)" "unprognostic (1.60e-2)" "unprognostic (3.11e-1)" "unprognostic (3.47e-2)" "unprognostic (1.97e-1)" "unprognostic (3.39e-1)" "unprognostic (7.99e-3)" "unprognostic (1.34e-2)" "unprognostic (7.05e-2)" "unprognostic (1.33e-1)" "unprognostic (6.55e-2)" "unprognostic (2.00e-2)" "unprognostic (2.33e-2)" "potential prognostic favorable (2.97e-4)" "unprognostic (4.69e-1)" "unprognostic (3.88e-1)" "unprognostic (3.55e-2)" "unprognostic (4.90e-2)" "unprognostic (3.60e-1)" "unprognostic (5.06e-2)" "unprognostic (8.32e-3)" "unprognostic (1.11e-1)" "unprognostic (6.00e-2)" "unprognostic (2.36e-2)" TBCEL "LRRC35, MGC10233" ENSG00000154114 "Tubulin folding cofactor E like" Q5QJ74 11 121024072-121090776 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 30.9;Bergmann glia: 30.7;Brain excitatory neurons: 46.0;Brain inhibitory neurons: 44.5;Choroid plexus epithelial cells: 172.3;Ependymal cells: 51.1;Microglia: 30.3;Oligodendrocyte progenitor cells: 49.8;Oligodendrocytes: 50.0;Other brain neurons: 49.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038593, HPA038594" Approved Approved Cytosol NA NA 26000 "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 55: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 22: Non-specific - Basic cellular functions" 4 Cytosol "HPA038593: , HPA038594: " "unprognostic (1.27e-1)" "unprognostic (1.09e-3)" "unprognostic (1.76e-1)" "unprognostic (2.34e-1)" "unprognostic (1.66e-1)" "unprognostic (5.74e-2)" "unprognostic (1.05e-1)" "unprognostic (2.27e-3)" "unprognostic (2.33e-1)" "unprognostic (1.71e-1)" "unprognostic (3.47e-3)" "potential prognostic favorable (6.53e-4)" "unprognostic (1.08e-1)" "unprognostic (4.12e-2)" "unprognostic (1.58e-1)" "unprognostic (9.25e-2)" "unprognostic (3.95e-1)" "unprognostic (2.36e-1)" "unprognostic (7.04e-2)" "unprognostic (6.86e-3)" "unprognostic (1.82e-3)" "unprognostic (3.50e-2)" "unprognostic (1.35e-1)" "unprognostic (1.72e-1)" "unprognostic (1.12e-1)" "unprognostic (4.83e-2)" "unprognostic (2.03e-2)" "unprognostic (1.35e-3)" "unprognostic (2.20e-1)" "unprognostic (5.53e-2)" "unprognostic (9.78e-2)" TBCEL-TECTA ENSG00000285509 "TBCEL-TECTA readthrough" 11 121024125-121113108 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Corticotrophs: 2.8;Lactotrophs: 2.8;Myosatellite cells: 2.7;Pituitary stem cells: 2.8;Plasma cells: 2.7;Somatotrophs: 4.6;Thyrotrophs: 3.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038593, HPA038594" Uncertain Approved Cytosol NA NA "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" Cytosol "HPA038593: , HPA038594: " TBCK "HSPC302, MGC16169" ENSG00000145348 "TBC1 domain containing kinase" Q8TEA7 4 106041599-106316683 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039951, HPA051611" Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 7: Non-specific - Transcription" 2 "Nucleoplasm, Nucleoli fibrillar center" "HPA039951: , HPA051611: " "unprognostic (1.48e-1)" "unprognostic (1.77e-2)" "unprognostic (4.52e-2)" "unprognostic (6.80e-3)" "unprognostic (5.49e-2)" "unprognostic (6.12e-3)" "unprognostic (1.38e-1)" "unprognostic (2.87e-2)" "unprognostic (8.87e-2)" "unprognostic (1.70e-1)" "validated prognostic favorable (6.24e-7)" "validated prognostic favorable (2.18e-4)" "unprognostic (7.47e-3)" "unprognostic (2.07e-1)" "unprognostic (1.82e-2)" "unprognostic (2.06e-1)" "unprognostic (1.90e-1)" "unprognostic (8.79e-2)" "unprognostic (3.96e-2)" "unprognostic (6.33e-2)" "unprognostic (5.52e-2)" "unprognostic (2.98e-2)" "unprognostic (1.51e-2)" "unprognostic (2.03e-1)" "unprognostic (8.13e-2)" "unprognostic (1.97e-1)" "unprognostic (1.11e-2)" "unprognostic (8.05e-2)" "unprognostic (2.74e-1)" "unprognostic (3.37e-2)" "unprognostic (2.33e-1)" TBK1 NAK ENSG00000183735 "TANK binding kinase 1" Q9UHD2 12 64452090-64502114 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Amyotrophic lateral sclerosis, Disease variant, Glaucoma, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 491.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Kidney - Endothelial cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045797, HPA060211" Uncertain Enhanced Nucleoplasm,Vesicles NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 39: Testis - Nuclear processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 61: BICR 18 - Protein kinases" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 141 Nucleoplasm Vesicles "HPA045797: , HPA060211: " "unprognostic (1.28e-2)" "unprognostic (1.13e-2)" "unprognostic (2.38e-1)" "unprognostic (2.14e-2)" "unprognostic (1.45e-2)" "unprognostic (3.43e-3)" "unprognostic (2.68e-1)" "unprognostic (1.47e-1)" "unprognostic (1.65e-1)" "unprognostic (6.36e-2)" "potential prognostic favorable (4.24e-9)" "unprognostic (3.02e-1)" "unprognostic (7.93e-2)" "unprognostic (2.88e-2)" "unprognostic (5.34e-3)" "potential prognostic unfavorable (1.50e-4)" "unprognostic (3.47e-2)" "unprognostic (1.72e-1)" "unprognostic (9.80e-2)" "unprognostic (6.74e-3)" "unprognostic (2.29e-2)" "unprognostic (1.08e-2)" "unprognostic (9.66e-2)" "unprognostic (1.59e-1)" "unprognostic (1.36e-1)" "unprognostic (4.80e-1)" "unprognostic (2.06e-1)" "unprognostic (9.58e-2)" "unprognostic (2.02e-1)" "unprognostic (2.01e-1)" "unprognostic (6.44e-2)" TBKBP1 "KIAA0775, ProSAPiP2" ENSG00000198933 "TBK1 binding protein 1" A7MCY6 17 47694161-47712052 "Predicted intracellular proteins" "Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 17.9;Esophageal apical cells: 19.3;Neutrophils: 35.1;Retinal pigment epithelial cells: 29.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.4" "Group enriched" "Detected in many" 6 "granulocytes: 2.4;NK-cells: 1.0;T-cells: 1.0" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062347, HPA064856" Approved Approved Nucleoplasm NA Yes "Cluster 21: Neutrophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 22 Nucleoplasm "HPA062347: , HPA064856: " "unprognostic (8.02e-2)" "unprognostic (3.20e-1)" "unprognostic (2.02e-2)" "unprognostic (1.07e-3)" "unprognostic (1.20e-1)" "unprognostic (8.28e-3)" "unprognostic (2.99e-1)" "unprognostic (6.88e-3)" "unprognostic (2.70e-1)" "unprognostic (4.59e-2)" "unprognostic (2.55e-1)" "unprognostic (1.13e-1)" "unprognostic (1.28e-1)" "unprognostic (4.04e-1)" "unprognostic (8.76e-2)" "unprognostic (6.15e-3)" "unprognostic (9.95e-2)" "unprognostic (1.31e-2)" "potential prognostic favorable (3.78e-4)" "unprognostic (1.91e-1)" "unprognostic (3.97e-3)" "potential prognostic favorable (5.52e-4)" "unprognostic (5.74e-3)" "unprognostic (2.39e-2)" "unprognostic (6.78e-2)" "potential prognostic favorable (9.45e-4)" "unprognostic (1.97e-3)" "unprognostic (2.23e-2)" "unprognostic (1.33e-1)" "unprognostic (8.78e-2)" "unprognostic (3.64e-2)" TBL1X "EBI, TBL1" ENSG00000101849 "Transducin beta like 1 X-linked" O60907 X 9463320-9741037 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" Activator "Congenital hypothyroidism, Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 696.7;Gonadotrophs: 800.9;Neutrophils: 1835.5;Somatotrophs: 689.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 19.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Sertoli cells" "CAB005363, HPA067703" Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 22: Epididymis - Mixed function" "Cluster 46: Brainstem - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 24: Neutrophils - Innate immunity signal integration" 26 Nucleoplasm Nucleoli "CAB005363: , HPA067703: " "unprognostic (5.17e-3)" "unprognostic (4.00e-3)" "unprognostic (8.78e-3)" "unprognostic (1.32e-1)" "unprognostic (2.73e-1)" "unprognostic (2.38e-2)" "unprognostic (1.05e-1)" "unprognostic (7.62e-2)" "unprognostic (9.71e-2)" "unprognostic (7.81e-2)" "potential prognostic favorable (2.90e-8)" "unprognostic (7.88e-2)" "unprognostic (4.57e-2)" "unprognostic (1.97e-3)" "unprognostic (2.00e-1)" "unprognostic (1.54e-1)" "unprognostic (4.79e-2)" "unprognostic (1.70e-2)" "unprognostic (2.33e-3)" "unprognostic (4.39e-1)" "unprognostic (3.56e-1)" "unprognostic (1.33e-3)" "unprognostic (3.85e-2)" "unprognostic (2.73e-1)" "unprognostic (2.12e-1)" "unprognostic (2.88e-2)" "unprognostic (1.09e-1)" "unprognostic (1.39e-1)" "unprognostic (9.99e-2)" "unprognostic (2.28e-3)" "unprognostic (5.90e-2)" TBL1XR1 "C21, DC42, FLJ12894, IRA1, TBLR1" ENSG00000177565 "TBL1X/Y related 1" Q9BZK7 3 177019340-177228000 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, Chromatin regulator, Repressor" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019182 Supported Approved Nucleoplasm NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 34: Non-specific - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 51: Secretory epithelial cells - Mixed function" 41 Nucleoplasm "HPA019182: " "unprognostic (2.64e-1)" "unprognostic (1.81e-1)" "unprognostic (2.79e-1)" "unprognostic (2.77e-3)" "unprognostic (9.84e-2)" "unprognostic (3.35e-1)" "unprognostic (1.43e-1)" "unprognostic (1.54e-3)" "unprognostic (1.46e-1)" "unprognostic (2.27e-1)" "potential prognostic favorable (2.97e-5)" "unprognostic (4.42e-2)" "unprognostic (1.19e-2)" "unprognostic (2.45e-2)" "potential prognostic unfavorable (2.34e-4)" "unprognostic (2.15e-2)" "unprognostic (4.35e-3)" "unprognostic (1.02e-1)" "unprognostic (3.38e-3)" "unprognostic (8.41e-3)" "unprognostic (1.02e-1)" "unprognostic (3.76e-3)" "unprognostic (4.16e-1)" "unprognostic (1.14e-1)" "unprognostic (4.73e-2)" "unprognostic (9.93e-3)" "unprognostic (1.86e-1)" "unprognostic (1.12e-1)" "unprognostic (1.70e-1)" "unprognostic (1.97e-2)" "unprognostic (2.67e-1)" TBL1Y TBL1 ENSG00000092377 "Transducin beta like 1 Y-linked" Q9BQ87 Y 6910686-7101970 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" Activator "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "prostate: 2.7;thyroid gland: 1.8" "Cell type enhanced" "Detected in many" "Adipocytes: 69.0;Basal prostatic cells: 46.0;Cholangiocytes: 37.3;Distal convoluted tubule cells: 57.1;Ependymal cells: 42.8;Myosatellite cells: 35.1;Prostatic glandular cells: 111.7;Prostatic hillock cells: 62.0;Renal connecting tubule cells: 30.5;Respiratory basal cells: 32.2" "Cell type enhanced" "Detected in many" "ependymal cell: 46.7;medium spiny neuron: 51.0;pericyte: 88.2" "Cancer enriched" "Detected in single" 6 "Prostate Adenocarcinoma (TCGA): 3.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lymphoma: 1.7;prostate cancer: 1.9" "Prostate - Prostate glandular cells" "HPA050857, HPA060073" Uncertain Supported Nucleoplasm NA NA "Cluster 33: Thyroid gland - Tissue development" "Cluster 33: Neurons - Mixed function" "Cluster 61: BICR 18 - Protein kinases" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 11 Nucleoplasm "HPA050857: , HPA060073: " "unprognostic (1.03e-1)" TBL2 "DKFZP43N024, WBSCR13, WS-betaTRP" ENSG00000106638 "Transducin beta like 2" Q9Y4P3 7 73567537-73578791 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 12.7" "Group enriched" "Detected in many" 4 "Early spermatids: 361.6;Late primary spermatocytes: 748.7;Late spermatids: 764.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007477, HPA051533" Supported Cytosol NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 21: Testis - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 36 Cytosol "HPA007477: , HPA051533: " "unprognostic (9.29e-2)" "unprognostic (4.83e-3)" "unprognostic (3.17e-1)" "potential prognostic unfavorable (1.44e-5)" "unprognostic (3.39e-1)" "unprognostic (1.60e-1)" "unprognostic (2.33e-2)" "unprognostic (5.56e-3)" "unprognostic (8.66e-2)" "unprognostic (7.42e-3)" "unprognostic (3.67e-2)" "unprognostic (2.25e-1)" "unprognostic (3.29e-1)" "unprognostic (2.24e-2)" "potential prognostic unfavorable (1.72e-4)" "potential prognostic unfavorable (6.64e-4)" "unprognostic (3.37e-1)" "unprognostic (1.31e-1)" "unprognostic (1.00e-1)" "unprognostic (4.35e-2)" "unprognostic (1.43e-1)" "unprognostic (8.24e-3)" "unprognostic (2.69e-1)" "unprognostic (3.03e-1)" "unprognostic (1.43e-1)" "unprognostic (2.49e-1)" "unprognostic (9.45e-2)" "unprognostic (6.11e-2)" "unprognostic (2.36e-1)" "unprognostic (3.22e-1)" "unprognostic (3.68e-2)" TBL3 "SAZD, UTP13" ENSG00000183751 "Transducin beta like 3" Q12788 16 1972053-1982929 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 123.5;Esophageal apical cells: 252.1;Late spermatids: 107.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042562, HPA055695" Enhanced Supported Enhanced Nucleoli NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 24: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 44 Nucleoli "HPA042562: , HPA055695: " "unprognostic (3.91e-2)" "unprognostic (2.36e-2)" "unprognostic (1.47e-2)" "unprognostic (1.63e-1)" "unprognostic (1.76e-3)" "unprognostic (5.51e-2)" "unprognostic (9.95e-2)" "unprognostic (2.07e-3)" "unprognostic (2.24e-1)" "unprognostic (4.02e-2)" "potential prognostic favorable (4.41e-6)" "unprognostic (4.34e-1)" "unprognostic (1.35e-1)" "unprognostic (6.57e-3)" "unprognostic (2.35e-2)" "unprognostic (4.93e-2)" "unprognostic (3.01e-2)" "unprognostic (2.60e-2)" "unprognostic (1.49e-2)" "unprognostic (6.54e-2)" "unprognostic (1.85e-1)" "unprognostic (4.78e-2)" "unprognostic (4.42e-2)" "unprognostic (4.83e-2)" "potential prognostic favorable (3.88e-4)" "unprognostic (2.56e-1)" "unprognostic (6.84e-2)" "unprognostic (2.44e-1)" "unprognostic (3.06e-1)" "unprognostic (3.67e-2)" "unprognostic (2.32e-1)" TBP "GTF2D1, SCA17, TBP1, TFIID" ENSG00000112592 "TATA-box binding protein" P20226 6 170554302-170572870 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" DNA-binding "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 152.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009442, HPA049805, HPA070500" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 39: Testis - Nuclear processes" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 28: Non-specific - Nuclear processes" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 179 Nucleoplasm Cytosol "CAB009442: , HPA049805: , HPA070500: " "unprognostic (1.47e-1)" "potential prognostic unfavorable (5.17e-4)" "unprognostic (4.13e-3)" "unprognostic (1.40e-3)" "unprognostic (5.45e-2)" "unprognostic (1.40e-1)" "unprognostic (2.63e-1)" "unprognostic (4.83e-2)" "unprognostic (1.64e-1)" "unprognostic (1.49e-2)" "unprognostic (1.33e-1)" "unprognostic (2.97e-2)" "unprognostic (6.05e-2)" "potential prognostic unfavorable (5.61e-9)" "unprognostic (2.25e-2)" "unprognostic (2.75e-2)" "unprognostic (1.52e-1)" "unprognostic (1.71e-2)" "unprognostic (2.46e-2)" "unprognostic (3.37e-3)" "unprognostic (1.22e-1)" "unprognostic (1.65e-2)" "unprognostic (6.32e-3)" "unprognostic (1.26e-1)" "unprognostic (1.95e-3)" "unprognostic (6.48e-2)" "unprognostic (4.04e-2)" "unprognostic (1.31e-1)" "unprognostic (9.41e-2)" "unprognostic (2.69e-1)" "unprognostic (1.41e-1)" TBPL1 "STUD, TLF, TLP, TRF2" ENSG00000028839 "TATA-box binding protein like 1" P62380 6 133952170-133990432 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 118.4" "Cell type enhanced" "Detected in many" "Early spermatids: 253.0;Late primary spermatocytes: 1117.5;Platelets: 217.5;Syncytiotrophoblasts: 324.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA071810, HPA071813" Enhanced Supported Nucleoplasm,Nucleoli NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 39: Testis - Nuclear processes" "Cluster 14: Neurons - Synaptic function" "Cluster 47: Leukemia - Hemostasis" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 16 Nucleoplasm Nucleoli "HPA071810: , HPA071813: " "unprognostic (1.44e-1)" "potential prognostic unfavorable (4.23e-5)" "unprognostic (4.82e-2)" "unprognostic (1.08e-3)" "unprognostic (1.57e-1)" "unprognostic (1.66e-1)" "unprognostic (1.33e-3)" "unprognostic (1.11e-2)" "unprognostic (1.19e-2)" "unprognostic (8.53e-2)" "validated prognostic favorable (3.02e-4)" "validated prognostic favorable (6.82e-4)" "unprognostic (3.26e-2)" "potential prognostic unfavorable (9.85e-5)" "unprognostic (5.80e-2)" "unprognostic (1.29e-1)" "unprognostic (1.45e-2)" "unprognostic (1.81e-1)" "unprognostic (1.99e-2)" "unprognostic (3.25e-3)" "unprognostic (4.64e-3)" "unprognostic (1.36e-2)" "unprognostic (6.46e-3)" "unprognostic (5.92e-2)" "unprognostic (1.56e-2)" "unprognostic (2.45e-2)" "unprognostic (2.78e-1)" "unprognostic (1.43e-1)" "unprognostic (2.51e-1)" "unprognostic (3.42e-2)" "unprognostic (9.25e-2)" TBPL2 "TBP2, TRF3" ENSG00000182521 "TATA-box binding protein like 2" Q6SJ96 14 55414210-55456726 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skeletal muscle: 1.4;skin 1: 1.2" "Cell type enriched" "Detected in some" 12 "Oocytes: 101.3" "Low cell type specificity" "Detected in some" "Cancer enriched" "Detected in many" 4 "Testicular Germ Cell Tumor (TCGA): 39.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" HPA056241 Uncertain NA NA "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 41: Oocytes - Oogenesis" 3 "HPA056241: " "unprognostic (3.78e-1)" "unprognostic (2.28e-1)" "unprognostic (3.42e-2)" "unprognostic (2.41e-1)" "unprognostic (4.19e-2)" "unprognostic (9.44e-3)" "potential prognostic unfavorable (6.20e-6)" "unprognostic (8.67e-3)" "unprognostic (3.63e-2)" "unprognostic (1.05e-1)" "unprognostic (1.86e-1)" "unprognostic (1.78e-2)" "unprognostic (1.53e-1)" "unprognostic (1.81e-3)" "unprognostic (2.04e-2)" "potential prognostic favorable (3.99e-5)" "unprognostic (5.74e-2)" "unprognostic (2.34e-1)" "unprognostic (2.05e-3)" "unprognostic (1.13e-1)" TBR1 ENSG00000136535 "T-box brain transcription factor 1" Q16650 2 161416297-161425870 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Autism spectrum disorder, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 39 "brain: 33.1" "Cell type enriched" "Detected in some" 5 "Late spermatids: 58.7" "Cell type enhanced" "Detected in some" "deep-layer corticothalamic and 6b: 28.2;deep-layer intratelencephalic: 19.8" "Group enriched" "Detected in some" 5 "Glioblastoma Multiforme (TCGA): 1.1;Testicular Germ Cell Tumor (TCGA): 1.4" "Region enhanced" "Detected in many" "cerebral cortex: 105.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 2.9;Rhabdoid: 2.3" "Testis - Late spermatids" "Group enriched" "Detected in many" 6 "amygdala: 44.6;basal ganglia: 28.3;cerebral cortex: 70.9;hippocampal formation: 45.7;white matter: 43.9" "Region enhanced" "Detected in many" "cerebral cortex: 87.1" "HPA051256, HPA078644, HPA078657" Enhanced Supported NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 35: Neurons - Synaptic function & neurogenesis" 10 "HPA051256: , HPA078644: , HPA078657: " "unprognostic (7.88e-3)" "unprognostic (2.95e-1)" "unprognostic (2.47e-1)" TBRG1 "FLJ14621, NIAM, TB-5" ENSG00000154144 "Transforming growth factor beta regulator 1" Q3YBR2 11 124622836-124635926 "Predicted intracellular proteins" "Cell cycle" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055645, HPA068022" Enhanced Nucleoplasm NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 33: Neurons - Mixed function" "Cluster 61: BICR 18 - Protein kinases" "Cluster 9: T-cells - Adaptive immunity: Regulation" 7 Nucleoplasm "HPA055645: , HPA068022: " "unprognostic (4.81e-2)" "unprognostic (5.09e-1)" "unprognostic (1.64e-2)" "potential prognostic unfavorable (8.53e-4)" "unprognostic (5.92e-2)" "unprognostic (8.51e-2)" "unprognostic (4.54e-2)" "unprognostic (1.59e-2)" "unprognostic (1.06e-1)" "unprognostic (1.20e-1)" "unprognostic (1.47e-1)" "unprognostic (4.53e-2)" "unprognostic (4.90e-3)" "unprognostic (1.83e-1)" "unprognostic (2.77e-2)" "unprognostic (9.45e-2)" "unprognostic (3.20e-1)" "unprognostic (1.76e-1)" "unprognostic (9.51e-3)" "unprognostic (1.22e-1)" "unprognostic (1.45e-1)" "unprognostic (8.91e-2)" "unprognostic (4.38e-2)" "unprognostic (7.30e-2)" "unprognostic (1.28e-1)" "unprognostic (1.33e-1)" "unprognostic (1.67e-3)" "unprognostic (6.05e-2)" "unprognostic (1.56e-2)" "unprognostic (3.31e-1)" "unprognostic (2.71e-1)" TBRG4 "Cpr2, FASTKD4, H_TD2522F11.8, KIAA0948" ENSG00000136270 "Transforming growth factor beta regulator 4" Q969Z0 7 45100100-45112047 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 80.4;Late primary spermatocytes: 103.4;Migrating cytotrophoblasts: 94.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020582, HPA050430" Approved Enhanced Mitochondria NA NA 32000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 45: Non-specific - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 27 Mitochondria "HPA020582: , HPA050430: " "unprognostic (2.24e-2)" "unprognostic (3.75e-2)" "unprognostic (6.65e-2)" "unprognostic (7.44e-2)" "unprognostic (1.92e-1)" "unprognostic (1.79e-2)" "unprognostic (2.88e-2)" "unprognostic (1.05e-1)" "unprognostic (4.88e-3)" "potential prognostic unfavorable (4.54e-6)" "unprognostic (4.14e-1)" "unprognostic (2.24e-1)" "unprognostic (1.28e-2)" "validated prognostic unfavorable (1.03e-4)" "validated prognostic unfavorable (1.22e-6)" "potential prognostic unfavorable (2.07e-4)" "unprognostic (2.52e-2)" "unprognostic (2.44e-2)" "unprognostic (3.56e-2)" "unprognostic (3.37e-1)" "unprognostic (2.91e-2)" "unprognostic (3.14e-1)" "unprognostic (1.96e-2)" "unprognostic (4.56e-2)" "unprognostic (2.19e-2)" "unprognostic (1.50e-1)" "unprognostic (2.23e-1)" "unprognostic (7.67e-2)" "unprognostic (3.76e-1)" "unprognostic (1.17e-1)" "unprognostic (2.90e-1)" TBX1 "CATCH22, VCF" ENSG00000184058 "T-box transcription factor 1" O43435 22 19756703-19783593 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "skeletal muscle: 77.1;tongue: 62.3" "Group enriched" "Detected in many" 7 "Early spermatids: 279.3;Late spermatids: 440.1;Lymphatic endothelial cells: 347.8" "Cell type enhanced" "Detected in some" "endothelial cell: 7.0" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 26.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 42.8" "Adipose subcutaneous - Smooth muscle cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA029330 Approved "Nuclear bodies,Cytoplasmic bodies" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 34: Non-specific - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 1 "Nuclear bodies, Cytoplasmic bodies" "HPA029330: " "unprognostic (2.22e-1)" "unprognostic (2.76e-1)" "unprognostic (1.31e-1)" "unprognostic (3.72e-3)" "unprognostic (1.88e-1)" "unprognostic (1.52e-1)" "unprognostic (1.80e-2)" "unprognostic (1.44e-1)" "unprognostic (2.59e-1)" "unprognostic (7.07e-2)" "unprognostic (2.15e-3)" "unprognostic (2.93e-2)" "unprognostic (4.73e-2)" "unprognostic (2.58e-2)" "unprognostic (1.79e-3)" "unprognostic (3.41e-2)" "unprognostic (2.79e-1)" "unprognostic (3.85e-1)" "unprognostic (1.50e-1)" "unprognostic (2.56e-1)" TBX10 "TBX13, TBX7" ENSG00000167800 "T-box transcription factor 10" O75333 11 67631303-67639763 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 13 "intestine: 7.9" "Group enriched" "Detected in some" 7 "Enterocytes: 41.1;Goblet cells: 138.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rectum Adenocarcinoma (TCGA): 4.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Colon - Colon enterocytes, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in single" "HPA047881, HPA076197" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 77: Intestine - Digestion" "Cluster 70: DU4475 - Unknown function" "Cluster 70: Intestinal goblet cells - Mucin production" Nucleoplasm Cytosol "HPA047881: , HPA076197: " "unprognostic (6.08e-2)" "unprognostic (3.68e-1)" "unprognostic (7.75e-2)" "unprognostic (3.05e-2)" "unprognostic (4.50e-1)" "unprognostic (2.96e-1)" "unprognostic (4.75e-2)" "unprognostic (1.67e-1)" TBX15 TBX14 ENSG00000092607 "T-box transcription factor 15" Q96SF7 1 118883046-118989556 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 43.7;skeletal muscle: 124.6;tongue: 107.3" "Cell type enhanced" "Detected in some" "Adipocytes: 118.4;Epididymal clear cells: 34.7;Fibro-adipogenic progenitors: 100.2;Fibroblasts: 33.3;Myonuclei: 315.5;Myosatellite cells: 67.4;Pericytes: 46.6;Thymic myoid cells: 115.6" "Group enriched" "Detected in some" 61 "fibroblast: 74.2;pericyte: 64.1;vascular associated smooth muscle cell: 41.9" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 19.8" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 13.0;Sarcoma: 11.8" "Testis - Early spermatids" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "spinal cord: 4.4" "HPA052245, HPA053713" Uncertain Approved Nucleoplasm,Centrosome NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 23: Choroid plexus - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 10 Nucleoplasm Centrosome "HPA052245: , HPA053713: " "unprognostic (3.52e-2)" "unprognostic (1.45e-1)" "unprognostic (1.28e-1)" "unprognostic (1.62e-1)" "unprognostic (2.36e-3)" "potential prognostic unfavorable (8.21e-5)" "unprognostic (9.33e-2)" "unprognostic (7.01e-2)" "potential prognostic unfavorable (4.23e-4)" "unprognostic (5.87e-2)" "unprognostic (6.36e-3)" "unprognostic (5.32e-2)" "unprognostic (3.57e-3)" "unprognostic (4.02e-1)" "unprognostic (1.45e-1)" "unprognostic (2.39e-1)" "unprognostic (2.12e-1)" "unprognostic (3.36e-3)" "unprognostic (2.51e-2)" "unprognostic (7.12e-2)" "potential prognostic unfavorable (2.16e-4)" "unprognostic (5.16e-2)" "unprognostic (5.97e-2)" TBX18 ENSG00000112837 "T-box transcription factor 18" O95935 6 84687351-84764598 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 34.2" "Cell type enhanced" "Detected in some" "Adipocytes: 51.3;Epicardial cells: 79.6;Fibro-adipogenic progenitors: 68.5;Fibroblasts: 69.0;Mesothelial cells: 25.2;Pericytes: 49.6;Smooth muscle cells: 30.1;Vascular smooth muscle cells: 127.7" "Cell type enhanced" "Detected in some" "fibroblast: 666.5;pericyte: 166.4;vascular associated smooth muscle cell: 459.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblasts_2, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA006807 Supported Nucleoplasm NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 22: Non-specific - Basic cellular functions" 5 Nucleoplasm "HPA006807: " "unprognostic (5.97e-2)" "unprognostic (6.82e-2)" "unprognostic (9.01e-2)" "unprognostic (8.02e-2)" "unprognostic (4.05e-1)" "unprognostic (2.08e-2)" "unprognostic (2.36e-1)" "unprognostic (1.90e-1)" "unprognostic (2.28e-1)" "unprognostic (2.07e-1)" "unprognostic (1.23e-1)" "unprognostic (2.35e-2)" "unprognostic (2.43e-1)" "unprognostic (1.36e-2)" "unprognostic (5.32e-2)" "unprognostic (3.79e-2)" "unprognostic (1.31e-3)" "unprognostic (1.28e-1)" "unprognostic (4.92e-2)" TBX19 "dj747L4.1, TPIT" ENSG00000143178 "T-box transcription factor 19" O60806 1 168280877-168314426 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "pituitary gland: 48.1" "Cell type enriched" "Detected in many" 12 "Corticotrophs: 634.5" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 27.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Pituitary gland - Corticotropes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA005800, HPA072686" Enhanced Approved "Nuclear speckles" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 20: Pituitary gland - Hormone signaling" "Cluster 46: Brainstem - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 13 "Nuclear speckles" "HPA005800: , HPA072686: " "unprognostic (2.40e-2)" "unprognostic (2.02e-1)" "unprognostic (5.00e-3)" "unprognostic (3.32e-3)" "unprognostic (2.88e-2)" "unprognostic (2.21e-1)" "unprognostic (3.95e-2)" "unprognostic (2.27e-1)" "unprognostic (5.99e-2)" "unprognostic (2.08e-2)" "unprognostic (1.85e-1)" "unprognostic (1.58e-1)" "unprognostic (1.16e-2)" "unprognostic (2.91e-2)" "unprognostic (1.59e-1)" "unprognostic (3.46e-2)" "unprognostic (1.21e-1)" "unprognostic (7.82e-2)" "unprognostic (7.87e-2)" "unprognostic (1.17e-1)" "unprognostic (8.62e-3)" "unprognostic (1.10e-1)" "unprognostic (1.12e-2)" "unprognostic (3.47e-2)" "unprognostic (2.88e-2)" "unprognostic (1.82e-1)" "unprognostic (5.15e-2)" "unprognostic (1.96e-1)" TBX2 ENSG00000121068 "T-box transcription factor 2" Q13207 17 61399843-61409466 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 71.7" "Cell type enhanced" "Detected in many" "Epididymal basal cells: 72.7;Epididymal clear cells: 81.7;Epididymal efferent duct absorptive cells: 166.2;Epididymal principal cells: 102.5;Müller glia: 177.0;Papillary tip epithelial cells: 84.8;Pericytes: 190.9;Peritubular myoid cells: 83.8;Renal collecting duct principal cells: 164.5;Renal connecting tubule cells: 207.6;Retinal bipolar cells: 151.5;Vascular smooth muscle cells: 255.6" "Group enriched" "Detected in some" 70 "pericyte: 228.0;vascular associated smooth muscle cell: 320.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "Neuroblastoma: 80.2;Rhabdoid: 81.4;skin cancer: 47.4" "Breast - Endothelial cells, Liver - Hepatic stellate cells, Minor Salivary Gland - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA008586, CAB013636" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 5: Rhabdoid - Unknown function" "Cluster 110: Mural cells - ECM organization" 9 Nucleoplasm Cytosol "CAB013636: , HPA008586: " "unprognostic (8.21e-2)" "unprognostic (2.63e-2)" "unprognostic (2.82e-1)" "unprognostic (2.92e-2)" "unprognostic (2.67e-2)" "unprognostic (3.60e-2)" "unprognostic (1.50e-1)" "unprognostic (4.49e-1)" "unprognostic (2.94e-1)" "unprognostic (5.42e-2)" "unprognostic (3.38e-3)" "potential prognostic favorable (2.83e-4)" "unprognostic (2.92e-2)" "unprognostic (3.19e-1)" "unprognostic (3.98e-1)" "unprognostic (2.23e-1)" "unprognostic (6.28e-2)" "unprognostic (2.23e-2)" "unprognostic (1.55e-1)" "unprognostic (1.26e-1)" "unprognostic (4.64e-2)" "unprognostic (7.17e-2)" "unprognostic (3.73e-2)" "unprognostic (1.76e-1)" "unprognostic (1.80e-1)" "unprognostic (2.57e-2)" "unprognostic (1.05e-1)" "unprognostic (6.08e-2)" "unprognostic (1.23e-1)" "unprognostic (5.28e-2)" "unprognostic (5.59e-2)" TBX20 ENSG00000164532 "T-box transcription factor 20" Q9UMR3 7 35202430-35254100 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Atrial septal defect, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "heart muscle: 37.4" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 533.3;Pituitary stem cells: 171.0" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "medulla oblongata: 2.8;pons: 9.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 11.0" "Adrenal gland - Adrenal medulla cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA007840 Approved "Nucleoli fibrillar center" NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 43: Hindbrain - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 7 "Nucleoli fibrillar center" "HPA007840: " "unprognostic (5.82e-2)" "unprognostic (9.89e-3)" "unprognostic (2.58e-2)" "unprognostic (4.09e-2)" TBX21 "T-bet, TBLYM" ENSG00000073861 "T-box transcription factor 21" Q9UL17 17 47733236-47746122 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Asthma, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 10.5;lung: 3.1;lymphoid tissue: 11.0" "Group enriched" "Detected in some" 14 "NK-cells: 95.2;T-cells: 41.1" "Cell type enriched" "Detected in single" 88 "leukocyte: 70.5" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 3.1" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "gdT-cell: 15.7;NK-cell: 14.3" "Group enriched" "Detected in many" 7 "NK-cells: 14.3;T-cells: 15.7" "Group enriched" "Detected in some" 15 "Leukemia: 2.8;lymphoma: 6.1" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Minor Salivary Gland - T-cells, Pancreas - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Skin - T-cells, Stomach - T-cells, Testis - Spermatogonia, Thyroid gland - T-cells" "Region enriched" "Detected in single" 27 "olfactory bulb: 22.1" "Region enriched" "Detected in some" 4 "olfactory bulb: 5.6" "CAB009524, CAB030043" Enhanced NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 4 "CAB009524: , CAB030043: " "unprognostic (5.06e-3)" "unprognostic (2.17e-3)" "unprognostic (5.51e-2)" "unprognostic (3.73e-2)" "unprognostic (6.24e-2)" "potential prognostic favorable (4.92e-4)" "unprognostic (6.63e-2)" "unprognostic (1.71e-1)" "unprognostic (4.01e-1)" "unprognostic (1.45e-1)" TBX22 "CLPA, CPX" ENSG00000122145 "T-box transcription factor 22" Q9Y458 X 80014753-80031774 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Deafness, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 20 "testis: 10.4;thyroid gland: 4.5" "Group enriched" "Detected in some" 4 "Ependymal cells: 2.7;Sertoli cells: 8.2" "Cell type enhanced" "Detected in some" "ependymal cell: 3.3;thalamic excitatory: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Sertoli cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 10 TBX3 "TBX3-ISO, UMS, XHL" ENSG00000135111 "T-box transcription factor 3" O15119 12 114670255-114684175 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 171.8" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 654.2;Basal prostatic cells: 211.0;Breast hormone-responsive cells: 236.9;Prostatic club cells: 337.0;Prostatic glandular cells: 411.3;Prostatic hillock cells: 229.0;Syncytiotrophoblasts: 843.3" "Group enriched" "Detected in some" 7 "endothelial cell: 84.1;pericyte: 137.8;vascular associated smooth muscle cell: 48.7" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 87.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 85.1;prostate cancer: 73.8" "Breast - Breast glandular cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA005799, HPA075876" Supported Nucleoplasm,Cytosol NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 6 Nucleoplasm Cytosol "HPA005799: , HPA075876: " "potential prognostic favorable (7.57e-5)" "unprognostic (1.98e-1)" "unprognostic (2.70e-1)" "unprognostic (1.23e-1)" "unprognostic (3.57e-1)" "unprognostic (2.02e-1)" "unprognostic (4.71e-2)" "unprognostic (3.05e-1)" "unprognostic (2.07e-2)" "unprognostic (1.97e-2)" "validated prognostic favorable (6.25e-4)" "validated prognostic favorable (8.84e-4)" "unprognostic (6.27e-3)" "unprognostic (2.31e-1)" "unprognostic (1.25e-1)" "unprognostic (1.64e-1)" "unprognostic (1.12e-1)" "unprognostic (1.38e-1)" "unprognostic (6.90e-2)" "unprognostic (1.25e-1)" "unprognostic (6.99e-2)" "unprognostic (2.82e-1)" "unprognostic (3.65e-2)" "unprognostic (4.11e-2)" "unprognostic (3.47e-1)" "unprognostic (4.31e-3)" "unprognostic (4.99e-2)" "unprognostic (2.86e-3)" "unprognostic (8.94e-2)" "unprognostic (1.99e-1)" "unprognostic (4.94e-2)" TBX4 ENSG00000121075 "T-box transcription factor 4" P57082 17 61452404-61485110 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lung: 30.9;placenta: 19.8;prostate: 8.4" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 3.9;Cone photoreceptor cells: 2.1;Early spermatids: 8.7;Epicardial cells: 2.3;Fibroblasts: 2.5;Late spermatids: 28.5;Pericytes: 8.6;Smooth muscle cells: 4.3;Vascular smooth muscle cells: 3.9" "Cell type enriched" "Detected in single" 8 "choroid plexus epithelial cell: 2.9" "Cancer enhanced" "Detected in some" "Lung Adenocarcinoma (TCGA): 4.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Gastric cancer: 4.6" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB032413, HPA044457" Uncertain Approved Vesicles NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 110: Mural cells - ECM organization" Vesicles "CAB032413: , HPA044457: " "unprognostic (2.45e-2)" "unprognostic (7.47e-2)" "unprognostic (7.40e-2)" "unprognostic (2.29e-3)" "potential prognostic favorable (7.43e-4)" "unprognostic (3.02e-2)" "unprognostic (3.65e-2)" "unprognostic (1.47e-1)" "unprognostic (1.59e-1)" "unprognostic (1.09e-1)" TBX5 HOS ENSG00000089225 "T-box transcription factor 5" Q99593 12 114353911-114408442 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Atrial fibrillation, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 73.6;lung: 17.2;placenta: 27.0" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 174.1;Epicardial cells: 13.6;Fibroblasts: 12.0;Müller glia: 10.9;Pericytes: 56.1;Retinal amacrine cells: 13.1;Retinal bipolar cells: 13.7;Retinal ganglion cells: 38.6;Vascular smooth muscle cells: 12.6" "Cell type enhanced" "Detected in some" "astrocyte: 2.8;lower rhombic lip: 3.0" "Cancer enhanced" "Detected in some" "Lung Adenocarcinoma (TCGA): 3.2" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "Bone cancer: 3.7" "Heart muscle - Cardiomyocytes, Prostate - Fibroblasts, Skin - Fibroblasts_2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA008786, HPA064683" Uncertain Approved Nucleoplasm NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 29: Forebrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 7 Nucleoplasm "HPA008786: , HPA064683: " "unprognostic (8.29e-2)" "unprognostic (1.91e-1)" "unprognostic (5.09e-2)" "unprognostic (1.09e-1)" "unprognostic (2.82e-2)" "unprognostic (2.33e-1)" "unprognostic (1.73e-2)" "unprognostic (1.17e-1)" "unprognostic (7.48e-2)" TBX6 ENSG00000149922 "T-box transcription factor 6" O95947 16 30085793-30091924 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" Dwarfism "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 13.3" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 29.4;Esophageal basal cells: 13.1;Esophageal suprabasal cells: 23.0;Ocular epithelial cells: 8.4;Papillary tip epithelial cells: 9.5;Prostatic club cells: 9.3;Prostatic hillock cells: 16.3;Urothelial cells: 8.4" "Cell type enhanced" "Detected in some" "astrocyte: 6.0;Bergmann glia: 4.7;ependymal cell: 4.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 7.5" "Prostate - Urothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA062498 Approved Nucleoplasm NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 6: Non-specific - Immune response" "Cluster 6: Leukemia - Signal transduction" "Cluster 85: Squamous epithelial cells - Keratinization" 33 Nucleoplasm "HPA062498: " "unprognostic (4.14e-2)" "unprognostic (2.43e-2)" "unprognostic (2.31e-1)" "unprognostic (1.82e-3)" "potential prognostic unfavorable (5.35e-4)" "unprognostic (1.47e-1)" "unprognostic (3.82e-2)" "unprognostic (1.57e-2)" "unprognostic (1.20e-1)" "unprognostic (3.49e-2)" "unprognostic (1.05e-1)" "unprognostic (1.14e-3)" "unprognostic (2.68e-1)" "unprognostic (5.37e-2)" "unprognostic (1.08e-2)" "unprognostic (1.63e-1)" "unprognostic (2.41e-2)" "unprognostic (2.02e-2)" "unprognostic (4.24e-2)" "unprognostic (2.94e-2)" "unprognostic (2.30e-2)" "unprognostic (2.74e-1)" "unprognostic (5.08e-3)" "unprognostic (9.95e-2)" "unprognostic (1.25e-1)" "unprognostic (1.92e-1)" "unprognostic (7.03e-2)" "unprognostic (6.42e-3)" "unprognostic (1.10e-1)" TBXA2R ENSG00000006638 "Thromboxane A2 receptor" P21731 19 3594507-3606875 "Disease related genes, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "blood vessel: 34.6" "Cell type enhanced" "Detected in some" "Hepatic stellate cells: 64.5;Megakaryocytes: 92.7;Platelets: 361.1" "Cell type enriched" "Detected in some" 4 "pericyte: 43.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 11.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA077366 Supported "Nuclear speckles,Plasma membrane" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 6: Non-specific - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 47: Platelets - Hemostasis" 20 "Plasma membrane" "Nuclear speckles" "HPA077366: " "unprognostic (6.48e-2)" "unprognostic (9.85e-2)" "unprognostic (7.09e-2)" "unprognostic (2.63e-1)" "unprognostic (1.49e-2)" "unprognostic (2.38e-1)" "unprognostic (7.24e-2)" "unprognostic (1.91e-1)" "unprognostic (2.67e-1)" "unprognostic (3.28e-2)" "validated prognostic favorable (7.55e-5)" "validated prognostic favorable (9.61e-6)" "unprognostic (1.22e-2)" "unprognostic (3.24e-2)" "potential prognostic favorable (7.80e-6)" "unprognostic (5.37e-2)" "unprognostic (5.59e-2)" "unprognostic (1.98e-2)" "unprognostic (4.04e-3)" "unprognostic (1.71e-2)" "unprognostic (1.06e-1)" "unprognostic (2.77e-2)" "unprognostic (1.36e-3)" "unprognostic (4.85e-2)" "unprognostic (7.26e-3)" "unprognostic (1.39e-1)" "unprognostic (4.51e-1)" "unprognostic (3.95e-2)" TBXAS1 "CYP5, CYP5A1, THAS, TS, TXAS, TXS" ENSG00000059377 "Thromboxane A synthase 1" P24557 7 139777051-140020325 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Isomerase, Lyase, Monooxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 54.1" "Cell type enhanced" "Detected in many" "Hematopoietic stem cells: 339.2;Kupffer cells: 675.4;Lacrimal acinar cells: 321.6;Macrophages: 682.4;Mast cells: 389.1;Megakaryocyte progenitors: 417.6;Megakaryocyte-Erythroid progenitors: 383.3;Microglia: 1054.5;monocytes: 892.9;Neutrophil progenitors: 401.9;Neutrophils: 2238.6;Platelets: 327.3" "Cell type enriched" "Detected in all" 6 "central nervous system macrophage: 1339.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 14 "basophil: 291.7;classical monocyte: 291.1;eosinophil: 315.0;intermediate monocyte: 436.4;myeloid DC: 113.8;neutrophil: 258.5;non-classical monocyte: 404.5" "Group enriched" "Detected in all" 23 "dendritic cells: 113.8;granulocytes: 315.0;monocytes: 436.4" "Cancer enhanced" "Detected in many" "Kidney cancer: 14.7;Leukemia: 15.2" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Lung - Macrophages, Pancreas - Macrophages, Pituitary gland - Macrophages, Skeletal muscle - Macrophages, Spleen - Macrophages, Testis - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA031257, HPA031258, HPA031259" Enhanced Approved "Endoplasmic reticulum,Cytosol" NA NA 940000 "Cluster 25: Non-specific - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 1 "Endoplasmic reticulum, Cytosol" "HPA031257: , HPA031258: , HPA031259: " "unprognostic (1.52e-2)" "unprognostic (1.85e-1)" "unprognostic (3.25e-1)" "unprognostic (1.22e-1)" "unprognostic (1.42e-1)" "unprognostic (2.25e-1)" "unprognostic (7.62e-2)" "unprognostic (8.14e-2)" "unprognostic (1.82e-1)" "unprognostic (8.38e-3)" "unprognostic (5.11e-3)" "unprognostic (3.69e-1)" "unprognostic (7.55e-2)" "unprognostic (8.92e-2)" "unprognostic (4.46e-1)" "unprognostic (3.26e-2)" "unprognostic (2.81e-1)" "unprognostic (5.39e-3)" "unprognostic (5.43e-2)" "unprognostic (9.39e-3)" "unprognostic (2.61e-1)" "unprognostic (2.26e-2)" "unprognostic (1.60e-1)" "unprognostic (1.04e-1)" "unprognostic (1.55e-1)" "unprognostic (2.95e-1)" "unprognostic (1.31e-1)" "unprognostic (2.29e-1)" "potential prognostic unfavorable (8.03e-4)" "unprognostic (2.21e-1)" "unprognostic (6.66e-2)" TBXT T ENSG00000164458 "T-box transcription factor T" O15178 6 166157656-166168700 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "parathyroid gland: 2.4;pituitary gland: 1.2" "Cell type enriched" "Detected in single" 6 "Somatotrophs: 3.8" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 12 "Testicular Germ Cell Tumor (TCGA): 9.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Leukemia: 2.4;lung cancer: 8.2;lymphoma: 6.1" "Pituitary gland - Somatotropes" "Not detected" "Not detected" "Not detected" "Not detected" HPA003322 Uncertain Supported Nucleoplasm NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 7 Nucleoplasm "HPA003322: " "unprognostic (3.47e-2)" TC2N "C14orf47, C2CD1, FLJ36557, MTAC2D1, Tac2-N" ENSG00000165929 "Tandem C2 domains, nuclear" Q8N9U0 14 91779746-91867536 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 97.9" "Cell type enhanced" "Detected in many" "Breast lactating cells: 103.7;Innate lymphoid cells: 60.6;NK-cells: 90.9;Pancreatic acinar cells: 57.3;Papillary tip epithelial cells: 111.4;Renal collecting duct principal cells: 107.3;T-cells: 233.2" "Cell type enriched" "Detected in many" 13 "leukocyte: 734.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 84.7" "Group enriched" "Detected in many" 47 "NK-cells: 39.3;T-cells: 84.7" "Cancer enhanced" "Detected in many" "breast cancer: 24.4" "Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Corticotropes" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA027549 Approved Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 27: T-cells - Unknown function" "Cluster 8: Pancreas - Proteolysis" "Cluster 39: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 9: T-cells - Adaptive immunity: Regulation" "Nucleoplasm, Nuclear bodies" "HPA027549: " "unprognostic (3.49e-2)" "unprognostic (7.63e-2)" "unprognostic (4.27e-2)" "unprognostic (1.35e-3)" "unprognostic (4.45e-2)" "unprognostic (2.35e-2)" "unprognostic (1.44e-3)" "unprognostic (2.01e-1)" "unprognostic (2.31e-2)" "unprognostic (1.28e-1)" "potential prognostic favorable (9.31e-7)" "unprognostic (7.76e-3)" "unprognostic (3.03e-2)" "unprognostic (1.50e-1)" "unprognostic (3.23e-1)" "unprognostic (2.04e-1)" "unprognostic (1.72e-2)" "unprognostic (1.74e-1)" "unprognostic (9.44e-2)" "unprognostic (2.54e-1)" "unprognostic (7.41e-2)" "potential prognostic unfavorable (5.11e-4)" "unprognostic (2.39e-1)" "unprognostic (7.32e-2)" "potential prognostic favorable (7.29e-4)" "unprognostic (1.12e-2)" "unprognostic (3.31e-1)" "unprognostic (2.95e-1)" "unprognostic (5.26e-2)" "unprognostic (8.67e-2)" "unprognostic (7.84e-2)" TCAF1 "FAM115A, GATD9A, KIAA0738" ENSG00000198420 "TRPM8 channel associated factor 1" Q9Y4C2 7 143851375-143902198 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 33.7;Bergmann glia: 44.4;Brain excitatory neurons: 60.7;Brain inhibitory neurons: 77.9;Choroid plexus epithelial cells: 40.1;Distal convoluted tubule cells: 51.5;Loop of henle epithelial cells: 47.0;Oligodendrocyte progenitor cells: 51.6;Oligodendrocytes: 35.8;Other brain neurons: 59.5;Papillary tip epithelial cells: 34.1;Podocytes: 77.7;Proximal tubule cells: 39.3;Renal collecting duct intercalated cells: 42.9;Renal collecting duct principal cells: 41.7;Renal connecting tubule cells: 46.1;Syncytiotrophoblasts: 37.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Lung - Fibroblasts_1, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011732 Approved Approved "Nuclear bodies,Vesicles,Cell Junctions" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 33: Neurons - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 102: Non-specific - Mixed function" 16 "Cell Junctions" "Nuclear bodies, Vesicles" "HPA011732: " "unprognostic (2.08e-1)" "unprognostic (1.07e-1)" "unprognostic (1.61e-1)" "unprognostic (1.58e-1)" "unprognostic (2.62e-2)" "unprognostic (8.22e-2)" "unprognostic (9.18e-2)" "unprognostic (1.41e-1)" "unprognostic (4.43e-2)" "potential prognostic favorable (6.56e-6)" "unprognostic (4.91e-2)" "unprognostic (3.28e-2)" "potential prognostic unfavorable (9.01e-5)" "unprognostic (1.74e-2)" "unprognostic (2.15e-2)" "unprognostic (1.98e-1)" "unprognostic (2.18e-1)" "unprognostic (3.87e-2)" "unprognostic (5.19e-2)" "unprognostic (9.20e-2)" "unprognostic (2.02e-2)" "unprognostic (8.83e-2)" "unprognostic (2.50e-1)" "unprognostic (9.51e-2)" "unprognostic (1.27e-1)" "unprognostic (1.84e-1)" "unprognostic (1.36e-1)" "unprognostic (1.60e-2)" "unprognostic (8.15e-2)" TCAF2 "FAM115C, FAM139A, FLJ40722, GATD9B" ENSG00000170379 "TRPM8 channel associated factor 2" A6NFQ2 7 143620952-143730410 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 5.7;Loop of henle epithelial cells: 6.4;Papillary tip epithelial cells: 25.2;Podocytes: 20.9;Proximal tubule cells: 7.6;Renal collecting duct intercalated cells: 16.2;Renal collecting duct principal cells: 18.6;Renal connecting tubule cells: 29.5" "Cell type enhanced" "Detected in many" "leukocyte: 6.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Kidney - Endothelial cells, Lung - Fibroblasts_1" "HPA038756, HPA038758" Uncertain Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 37: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 105: Non-specific - Mixed function" 1 "Plasma membrane, Cell Junctions" "HPA038756: , HPA038758: " "unprognostic (2.15e-2)" "unprognostic (1.29e-1)" "unprognostic (1.73e-1)" "unprognostic (7.30e-2)" "unprognostic (1.10e-1)" "potential prognostic unfavorable (5.99e-4)" "unprognostic (1.08e-1)" "unprognostic (9.26e-2)" "unprognostic (1.11e-1)" "unprognostic (3.98e-3)" "unprognostic (2.82e-2)" "unprognostic (5.83e-2)" "unprognostic (3.38e-2)" "unprognostic (3.87e-1)" "unprognostic (2.22e-3)" "unprognostic (1.51e-2)" "unprognostic (3.22e-1)" "unprognostic (1.01e-1)" "unprognostic (2.42e-1)" "unprognostic (7.26e-2)" "unprognostic (4.79e-3)" "unprognostic (4.71e-2)" "unprognostic (5.00e-3)" "unprognostic (4.74e-1)" "unprognostic (6.83e-2)" "unprognostic (1.64e-1)" "unprognostic (2.67e-3)" "unprognostic (2.12e-1)" TCAF2C ENSG00000283528 "TRPM8 channel associated factor 2C" 7 143639230-143647646 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "HPA038756, HPA038758" Uncertain Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 55: Lymphoma - Immune response" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" "Plasma membrane, Cell Junctions" "HPA038756: , HPA038758: " TCAIM "C3orf23, DKFZp313N0621, TOAG-1" ENSG00000179152 "T cell activation inhibitor, mitochondrial" Q8N3R3 3 44338119-44409451 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 40.1" "Cell type enhanced" "Detected in all" "Distal convoluted tubule cells: 243.4;Myonuclei: 200.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 25: Non-specific - Transcription" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" "unprognostic (2.90e-1)" "unprognostic (1.60e-1)" "unprognostic (1.13e-1)" "unprognostic (1.92e-2)" "unprognostic (5.67e-2)" "unprognostic (2.59e-1)" "unprognostic (1.81e-1)" "unprognostic (2.97e-2)" "potential prognostic unfavorable (2.56e-4)" "potential prognostic favorable (1.09e-7)" "unprognostic (1.83e-2)" "unprognostic (6.44e-2)" "unprognostic (6.76e-2)" "unprognostic (2.26e-2)" "unprognostic (6.73e-2)" "unprognostic (1.63e-2)" "unprognostic (2.89e-2)" "unprognostic (2.25e-2)" "unprognostic (5.96e-2)" "unprognostic (8.38e-3)" "unprognostic (2.32e-1)" "unprognostic (4.57e-2)" "unprognostic (9.34e-3)" "unprognostic (5.97e-2)" "unprognostic (1.32e-1)" "unprognostic (1.72e-1)" "unprognostic (7.90e-2)" "unprognostic (3.70e-2)" "unprognostic (2.57e-1)" TCAP "CMD1N, LGMD2G, T-cap, TELE, telethonin" ENSG00000173991 Titin-cap O15273 17 39665349-39666554 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cardiomyopathy, Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 50 "heart muscle: 6421.7;skeletal muscle: 14837.4;tongue: 5443.8" "Cell type enriched" "Detected in many" 7 "Thymic myoid cells: 2592.8" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 72.9;Prostate Adenocarcinoma (TCGA): 36.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes" "Region enhanced" "Detected in many" "cerebral cortex: 15.8" "Low region specificity" "Detected in many" "CAB004591, HPA026477" Enhanced NA NA 15000 "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 19: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 59 "CAB004591: , HPA026477: " "unprognostic (1.27e-1)" "unprognostic (2.99e-1)" "unprognostic (9.02e-2)" "unprognostic (3.12e-2)" "potential prognostic unfavorable (2.38e-5)" "unprognostic (9.02e-2)" "potential prognostic favorable (5.70e-5)" "unprognostic (7.88e-3)" "unprognostic (4.52e-2)" "unprognostic (1.58e-1)" "unprognostic (1.98e-1)" "unprognostic (1.01e-2)" "unprognostic (7.04e-2)" "unprognostic (7.02e-2)" "potential prognostic favorable (1.02e-4)" "unprognostic (1.10e-1)" "unprognostic (1.87e-1)" "unprognostic (3.10e-2)" "unprognostic (3.81e-1)" "unprognostic (1.63e-1)" TCEA1 "GTF2S, SII, TCEA, TF2S, TFIIS" ENSG00000187735 "Transcription elongation factor A1" P23193 8 53966552-54022456 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043786 Approved Supported Nucleoplasm,Nucleoli NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 13: Non-specific - Mixed function" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 28 Nucleoplasm Nucleoli "HPA043786: " "unprognostic (6.60e-2)" "unprognostic (9.41e-2)" "unprognostic (1.12e-1)" "unprognostic (2.07e-1)" "unprognostic (3.20e-1)" "unprognostic (1.08e-1)" "unprognostic (1.59e-1)" "unprognostic (1.97e-1)" "unprognostic (9.76e-2)" "unprognostic (2.53e-3)" "potential prognostic favorable (1.99e-4)" "unprognostic (1.20e-1)" "unprognostic (1.03e-2)" "unprognostic (1.09e-2)" "unprognostic (5.66e-3)" "unprognostic (1.40e-2)" "unprognostic (1.35e-1)" "unprognostic (1.58e-1)" "unprognostic (3.63e-1)" "unprognostic (6.59e-2)" "unprognostic (1.40e-3)" "unprognostic (6.86e-3)" "unprognostic (1.12e-2)" "unprognostic (3.43e-1)" "unprognostic (3.08e-1)" "unprognostic (7.01e-2)" "unprognostic (3.27e-1)" "unprognostic (1.79e-2)" "unprognostic (1.59e-1)" "unprognostic (1.68e-1)" "unprognostic (5.74e-2)" TCEA2 TFIIS ENSG00000171703 "Transcription elongation factor A2" Q15560 20 64049836-64072347 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 189.2;Late spermatids: 259.5;Megakaryocytes: 197.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Liver - Hepatocytes, Skeletal muscle - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043836 Approved Supported "Nucleoplasm,Centrosome,Basal body" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 95 Nucleoplasm "Centrosome, Basal body" "HPA043836: " "unprognostic (2.45e-1)" "unprognostic (1.82e-1)" "unprognostic (1.27e-1)" "unprognostic (5.30e-2)" "unprognostic (4.29e-2)" "unprognostic (8.89e-3)" "unprognostic (1.06e-1)" "unprognostic (1.99e-1)" "unprognostic (2.03e-2)" "unprognostic (1.29e-1)" "unprognostic (3.68e-2)" "unprognostic (2.87e-1)" "unprognostic (6.53e-3)" "unprognostic (8.00e-2)" "unprognostic (1.19e-3)" "unprognostic (1.96e-1)" "unprognostic (1.61e-1)" "unprognostic (2.24e-1)" "unprognostic (1.92e-1)" "unprognostic (8.52e-2)" "unprognostic (2.53e-1)" "unprognostic (1.25e-2)" "unprognostic (2.73e-2)" "unprognostic (1.17e-1)" "unprognostic (1.70e-1)" "unprognostic (7.26e-3)" "unprognostic (1.47e-1)" "unprognostic (1.07e-2)" "unprognostic (6.68e-2)" "unprognostic (1.49e-1)" "unprognostic (2.28e-1)" TCEA3 TFIIS.H ENSG00000204219 "Transcription elongation factor A3" O75764 1 23380909-23424748 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 446.3" "Cell type enhanced" "Detected in many" "Colonocytes: 166.7;Enteric stem cells: 151.2;Enteric transient amplifying cells: 168.8;Gastric chief cells: 122.3;Gastric progenitor cells: 179.4;Goblet cells: 274.4;Granulosa cells: 157.3;Hepatocytes: 168.0;Parietal cells: 122.0" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 35.7;fibroblast: 59.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory CD4 T-cell: 8.4;naive CD4 T-cell: 13.7" "Lineage enriched" "Detected in many" 5 "T-cells: 13.7" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Skeletal muscle - Skeletal myocytes, Skin - Keratinocyte (other), Testis - Peritubular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA044960, HPA055811" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 8: Immune cells - Immune response" "Cluster 60: Prostate cancer - Unknown function" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 1 Nucleoplasm Vesicles "HPA044960: , HPA055811: " "unprognostic (1.02e-2)" "unprognostic (3.21e-1)" "unprognostic (1.98e-1)" "unprognostic (1.15e-2)" "unprognostic (2.29e-1)" "unprognostic (1.79e-1)" "validated prognostic unfavorable (5.76e-4)" "validated prognostic unfavorable (4.54e-4)" "potential prognostic favorable (1.37e-4)" "unprognostic (5.92e-2)" "potential prognostic favorable (1.56e-5)" "unprognostic (2.06e-3)" "potential prognostic favorable (4.17e-4)" "unprognostic (3.82e-2)" "unprognostic (6.59e-3)" "unprognostic (3.99e-3)" "unprognostic (1.69e-1)" "unprognostic (1.56e-1)" "unprognostic (7.06e-2)" "unprognostic (2.04e-1)" "unprognostic (1.76e-1)" "unprognostic (4.29e-2)" "potential prognostic favorable (9.04e-4)" "unprognostic (2.35e-1)" "unprognostic (1.43e-1)" "unprognostic (1.52e-2)" "unprognostic (4.51e-2)" "unprognostic (4.76e-1)" "unprognostic (1.17e-1)" "unprognostic (4.64e-2)" "unprognostic (4.05e-2)" TCEAL1 "p21, pp21, SIIR, WEX9" ENSG00000172465 "Transcription elongation factor A like 1" Q15170 X 103628704-103630953 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 270.0;Leydig cells: 243.8;Ovarian stromal cells: 245.9;Peritubular myoid cells: 365.2;Smooth muscle cells: 238.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in all" 4 "Adrenocortical cancer: 128.7" "Adipose subcutaneous - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057345, HPA060384, HPA076762" Approved Enhanced Nucleoplasm No No "Cluster 24: Non-specific - Transcription" "Cluster 75: Ovary - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 36: Non-specific - mRNA processing" "Cluster 94: Gonadal somatic cells - Mixed function" 6 Nucleoplasm "HPA057345: , HPA060384: , HPA076762: " "potential prognostic favorable (3.13e-4)" "unprognostic (1.44e-2)" "unprognostic (1.29e-2)" "unprognostic (1.41e-2)" "unprognostic (1.45e-1)" "unprognostic (2.52e-1)" "unprognostic (1.84e-1)" "unprognostic (1.79e-1)" "unprognostic (1.32e-1)" "unprognostic (2.76e-2)" "potential prognostic favorable (2.35e-9)" "unprognostic (3.23e-3)" "unprognostic (2.15e-1)" "unprognostic (2.84e-1)" "unprognostic (2.02e-1)" "unprognostic (3.53e-2)" "unprognostic (2.29e-1)" "unprognostic (1.84e-1)" "unprognostic (3.62e-1)" "unprognostic (2.18e-1)" "unprognostic (1.02e-1)" "unprognostic (2.73e-2)" "unprognostic (3.69e-2)" "unprognostic (1.89e-1)" "unprognostic (6.50e-2)" "unprognostic (2.36e-1)" "unprognostic (1.27e-2)" "unprognostic (2.57e-1)" "unprognostic (1.58e-1)" "unprognostic (1.59e-1)" "unprognostic (1.02e-1)" TCEAL2 "my048, MY0876G05, WEX1" ENSG00000184905 "Transcription elongation factor A like 2" Q9H3H9 X 102125679-102140426 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 243.0;pituitary gland: 179.4" "Cell type enhanced" "Detected in many" "Corticotrophs: 86.7;Epididymal basal cells: 68.5;Gonadotrophs: 75.7;Granulosa cells: 182.5;Lacrimal acinar cells: 92.4;Müller glia: 128.3;Other brain neurons: 74.3;Ovarian stromal cells: 106.1;Pancreatic islet cells: 91.5;Pituicytes/FSCs: 76.9;Retinal bipolar cells: 80.2;Salivary acinar cells: 66.7;Salivary myoepithelial cells: 74.9;Sertoli cells: 94.5;Smooth muscle cells: 96.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 58.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 8.0" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" HPA076317 Approved "Nuclear speckles,Cytosol" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 65: Brain - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 94: Gonadal somatic cells - Mixed function" 4 "Nuclear speckles" Cytosol "HPA076317: " "unprognostic (7.04e-2)" "unprognostic (3.57e-3)" "unprognostic (6.70e-2)" "potential prognostic favorable (3.86e-4)" "unprognostic (1.50e-1)" "potential prognostic favorable (1.73e-4)" "unprognostic (2.67e-1)" "unprognostic (6.83e-3)" "unprognostic (1.76e-2)" "unprognostic (6.20e-2)" "unprognostic (1.27e-2)" "unprognostic (9.03e-3)" "unprognostic (2.84e-1)" "unprognostic (1.07e-1)" "unprognostic (1.55e-1)" "unprognostic (9.77e-2)" "unprognostic (8.70e-3)" "unprognostic (2.27e-2)" "unprognostic (1.07e-1)" "unprognostic (9.22e-3)" "unprognostic (6.10e-2)" "unprognostic (4.49e-2)" "unprognostic (2.70e-2)" TCEAL3 "MGC15737, WEX8" ENSG00000196507 "Transcription elongation factor A like 3" Q969E4 X 103607451-103629690 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 349.2;Epididymal basal cells: 195.5;Epididymal principal cells: 196.5;Ovarian stromal cells: 260.7;Peritubular myoid cells: 234.3;Smooth muscle cells: 319.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Prostate - Smooth muscle cells, Spleen - Fibroblasts_2" "HPA045564, HPA058982" Uncertain Uncertain Nucleoplasm NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 74: Non-specific - Signal transduction" "Cluster 6: Non-specific - Immune response" "Cluster 36: Non-specific - mRNA processing" "Cluster 62: Smooth muscle cells - Muscle contraction" 1 Nucleoplasm "HPA045564: , HPA058982: " "potential prognostic favorable (1.62e-6)" "unprognostic (5.82e-2)" "unprognostic (1.56e-2)" "unprognostic (2.28e-1)" "unprognostic (6.51e-2)" "unprognostic (2.11e-1)" "unprognostic (1.14e-1)" "unprognostic (2.26e-1)" "unprognostic (7.36e-3)" "unprognostic (6.94e-2)" "unprognostic (3.37e-3)" "unprognostic (1.57e-2)" "unprognostic (1.15e-1)" "unprognostic (2.18e-1)" "unprognostic (6.39e-2)" "unprognostic (8.23e-3)" "unprognostic (5.08e-2)" "unprognostic (1.16e-1)" "unprognostic (5.60e-2)" "unprognostic (6.22e-2)" "unprognostic (8.63e-2)" "potential prognostic favorable (3.03e-4)" "unprognostic (2.18e-1)" "unprognostic (3.28e-1)" "unprognostic (1.89e-2)" "unprognostic (7.66e-2)" "unprognostic (4.88e-1)" "unprognostic (2.45e-2)" "unprognostic (1.30e-1)" "unprognostic (1.84e-1)" "unprognostic (2.14e-1)" TCEAL4 "FLJ21174, WEX7" ENSG00000133142 "Transcription elongation factor A like 4" Q96EI5 X 103576231-103587729 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 1537.7;Epididymal principal cells: 639.3;Hepatic stellate cells: 1052.1;Leydig cells: 1163.7;Ovarian stromal cells: 1413.1;Peritubular myoid cells: 1642.0;Smooth muscle cells: 967.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Fibroblasts, Prostate - Smooth muscle cells, Spleen - Fibroblasts_2" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 75: Ovary - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 36: Non-specific - mRNA processing" "Cluster 94: Gonadal somatic cells - Mixed function" 6 "unprognostic (1.91e-3)" "unprognostic (1.05e-1)" "unprognostic (4.86e-2)" "unprognostic (3.19e-1)" "unprognostic (5.33e-2)" "unprognostic (1.20e-1)" "unprognostic (2.12e-1)" "unprognostic (3.15e-1)" "potential prognostic unfavorable (2.89e-4)" "unprognostic (7.88e-2)" "potential prognostic favorable (2.44e-5)" "unprognostic (4.66e-2)" "unprognostic (3.83e-1)" "unprognostic (1.15e-1)" "unprognostic (5.37e-2)" "unprognostic (1.27e-1)" "unprognostic (1.82e-1)" "unprognostic (2.90e-2)" "unprognostic (2.35e-2)" "unprognostic (1.21e-1)" "unprognostic (1.75e-1)" "unprognostic (1.36e-2)" "unprognostic (3.13e-2)" "unprognostic (2.48e-1)" "unprognostic (1.80e-1)" "unprognostic (5.87e-2)" "unprognostic (1.27e-2)" "unprognostic (1.82e-2)" "unprognostic (3.14e-2)" "unprognostic (9.24e-2)" "unprognostic (3.36e-2)" TCEAL5 WEX4 ENSG00000204065 "Transcription elongation factor A like 5" Q5H9L2 X 103273691-103276750 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 113.7;pituitary gland: 67.3;testis: 65.5" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 18.9;Lactotrophs: 18.3;Late spermatids: 25.2;Müller glia: 53.5;Other brain neurons: 16.5;Pancreatic islet cells: 18.4;Peritubular myoid cells: 26.9;Pituicytes/FSCs: 16.8;Retinal amacrine cells: 28.4;Retinal bipolar cells: 25.8;Sertoli cells: 110.8;Somatotrophs: 16.1" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 27.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "Neuroblastoma: 24.3" "Adrenal gland - Adrenal medulla cells, Lung - Fibroblasts_2, Minor Salivary Gland - Smooth muscle cells, Pancreas - Alpha cells, Prostate - Fibroblasts, Stomach - Fibroblasts, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "HPA045564, HPA058982" Supported Approved Nucleoplasm NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 2 Nucleoplasm "HPA045564: , HPA058982: " "unprognostic (2.35e-1)" "unprognostic (2.73e-2)" "unprognostic (1.94e-2)" "unprognostic (2.31e-1)" "unprognostic (8.86e-2)" "unprognostic (3.38e-3)" "unprognostic (2.12e-1)" "potential prognostic favorable (4.38e-4)" "unprognostic (5.39e-3)" "unprognostic (2.36e-1)" "unprognostic (4.02e-1)" TCEAL6 WEX2 ENSG00000204071 "Transcription elongation factor A like 6" Q6IPX3 X 102140476-102142970 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 95.6;pituitary gland: 67.7;testis: 25.1" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 21.9;Brain inhibitory neurons: 20.0;Corticotrophs: 12.3;Gonadotrophs: 30.5;Granulosa cells: 38.9;Lactotrophs: 26.8;Other brain neurons: 36.9;Pituicytes/FSCs: 25.0;Retinal amacrine cells: 17.6;Retinal bipolar cells: 21.9;Sertoli cells: 43.3;Smooth muscle cells: 18.5;Somatotrophs: 24.9;Thyrotrophs: 22.1" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in single" 12 "Glioblastoma Multiforme (TCGA): 8.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Minor Salivary Gland - Smooth muscle cells, Skin - Eccrine sweat gland cells, Testis - Sertoli cells" "HPA045564, HPA058982" Supported Uncertain Nucleoplasm NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 1: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 98: Neurons - Neurotransmission & signaling" Nucleoplasm "HPA045564: , HPA058982: " "unprognostic (3.17e-3)" "unprognostic (7.36e-2)" TCEAL7 "MGC23947, WEX5" ENSG00000182916 "Transcription elongation factor A like 7" Q9BRU2 X 103330229-103332326 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 120.5" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 35.9;Brain inhibitory neurons: 34.6;Breast myoepithelial cells: 55.1;Decidual stromal cells: 78.6;Endometrial stromal cells: 35.5;Fibroblasts: 34.2;Granulosa cells: 51.1;Müller glia: 88.0;Oligodendrocytes: 45.2;Other brain neurons: 71.6;Ovarian stromal cells: 64.5;Peritubular myoid cells: 36.0;Pituicytes/FSCs: 32.7;Retinal amacrine cells: 38.3;Retinal horizontal cells: 34.1;Schwann cells: 32.4;Smooth muscle cells: 30.7" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 11 "Glioblastoma Multiforme (TCGA): 76.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Brain cancer: 16.8;Neuroblastoma: 58.0;Sarcoma: 16.5" "Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA051507, HPA065080" Enhanced Supported Nucleoplasm NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 98: Neurons - Neurotransmission & signaling" Nucleoplasm "HPA051507: , HPA065080: " "unprognostic (2.03e-2)" "unprognostic (8.01e-2)" "unprognostic (3.63e-2)" "unprognostic (8.82e-2)" "unprognostic (3.49e-2)" "unprognostic (2.35e-1)" "unprognostic (1.41e-1)" "unprognostic (1.55e-1)" "unprognostic (2.26e-2)" "unprognostic (7.30e-2)" "unprognostic (4.61e-3)" "unprognostic (3.24e-3)" "unprognostic (1.33e-2)" "unprognostic (2.16e-2)" "unprognostic (4.95e-3)" "unprognostic (1.82e-1)" "unprognostic (5.28e-2)" "unprognostic (2.46e-1)" "unprognostic (1.33e-1)" "unprognostic (1.38e-3)" "unprognostic (3.90e-1)" "unprognostic (5.64e-2)" "unprognostic (2.68e-2)" "unprognostic (1.66e-1)" "unprognostic (1.32e-1)" "potential prognostic unfavorable (1.06e-4)" "unprognostic (1.72e-1)" "unprognostic (4.06e-2)" "unprognostic (1.28e-1)" TCEAL8 "MGC45400, WEX3" ENSG00000180964 "Transcription elongation factor A like 8" Q8IYN2 X 103252995-103255192 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 359.5;Megakaryocytes: 358.5;Migrating cytotrophoblasts: 274.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Skeletal muscle - Fibroblasts, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059115 Uncertain Approved Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 22: Epididymis - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 97: Non-specific - Cellular respiration" 8 Nucleoplasm "HPA059115: " "unprognostic (1.85e-1)" "unprognostic (3.07e-2)" "unprognostic (3.93e-1)" "unprognostic (2.23e-2)" "unprognostic (1.38e-1)" "unprognostic (2.92e-1)" "unprognostic (5.87e-2)" "unprognostic (2.49e-1)" "potential prognostic unfavorable (4.15e-5)" "unprognostic (2.07e-1)" "potential prognostic favorable (2.26e-7)" "unprognostic (5.62e-2)" "unprognostic (2.15e-1)" "unprognostic (7.30e-3)" "unprognostic (2.46e-2)" "unprognostic (2.55e-2)" "unprognostic (3.39e-2)" "unprognostic (1.83e-1)" "unprognostic (5.59e-2)" "unprognostic (2.42e-2)" "unprognostic (1.20e-2)" "unprognostic (1.16e-1)" "unprognostic (9.03e-2)" "unprognostic (1.44e-1)" "unprognostic (2.41e-1)" "unprognostic (3.95e-2)" "unprognostic (3.73e-2)" "unprognostic (4.14e-2)" "unprognostic (2.70e-1)" "unprognostic (3.90e-1)" "unprognostic (6.72e-2)" TCEAL9 "DKFZp313K1940, WBP5, WEX6" ENSG00000185222 "Transcription elongation factor A like 9" Q9UHQ7 X 103356489-103358462 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1283.0;Epididymal basal cells: 623.1;Epididymal principal cells: 522.8;Extravillous trophoblasts: 468.4;Granulosa cells: 466.3;Megakaryocytes: 562.5;Migrating cytotrophoblasts: 1072.3;Ovarian stromal cells: 554.6;Syncytiotrophoblasts: 911.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "plasmacytoid DC: 23.6" "Lineage enriched" "Detected in all" 6 "dendritic cells: 23.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011790, HPA012106" Uncertain Approved Nucleoplasm,Nucleoli NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 36: Non-specific - mRNA processing" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 8 "Nucleoplasm, Nucleoli" "HPA011790: , HPA012106: " "unprognostic (7.91e-2)" "unprognostic (1.56e-2)" "unprognostic (7.63e-2)" "unprognostic (7.08e-2)" "unprognostic (1.34e-1)" "unprognostic (1.41e-1)" "unprognostic (6.84e-3)" "potential prognostic unfavorable (1.71e-4)" "unprognostic (1.02e-2)" "unprognostic (1.80e-2)" "unprognostic (1.65e-1)" "unprognostic (1.20e-3)" "potential prognostic unfavorable (2.57e-4)" "unprognostic (6.14e-3)" "unprognostic (4.49e-2)" "unprognostic (4.78e-2)" "unprognostic (2.06e-1)" "unprognostic (1.64e-2)" "unprognostic (2.49e-1)" "unprognostic (1.19e-2)" "unprognostic (2.82e-2)" "unprognostic (5.10e-2)" "unprognostic (1.26e-1)" "unprognostic (8.86e-2)" "unprognostic (4.45e-2)" "unprognostic (3.53e-3)" "unprognostic (2.74e-1)" "unprognostic (1.57e-2)" "unprognostic (2.79e-1)" TCEANC MGC17403 ENSG00000176896 "Transcription elongation factor A N-terminal and central domain containing" Q8N8B7 X 13653112-13681964 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Myonuclei: 16.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000337, HPA001013" Uncertain Approved "Nuclear speckles" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 47: Leukemia - Hemostasis" "Cluster 44: Plasma cells - Antibody production & secretion" 27 "Nuclear speckles" "HPA000337: , HPA001013: " "unprognostic (5.26e-2)" "unprognostic (1.24e-2)" "unprognostic (2.91e-2)" "unprognostic (4.92e-2)" "unprognostic (1.47e-1)" "unprognostic (8.21e-3)" "unprognostic (6.36e-2)" "unprognostic (1.10e-2)" "unprognostic (3.38e-2)" "unprognostic (1.07e-1)" "unprognostic (1.06e-1)" "unprognostic (3.20e-3)" "unprognostic (3.02e-2)" "unprognostic (3.57e-3)" "unprognostic (2.96e-1)" "unprognostic (6.83e-2)" "unprognostic (1.19e-2)" "unprognostic (2.86e-2)" "unprognostic (8.78e-3)" "potential prognostic favorable (7.76e-4)" "unprognostic (9.31e-2)" "unprognostic (7.30e-2)" "unprognostic (3.96e-2)" "unprognostic (7.59e-2)" "unprognostic (6.15e-2)" "unprognostic (1.89e-1)" "unprognostic (1.93e-1)" "unprognostic (8.50e-2)" "unprognostic (1.69e-1)" TCEANC2 "C1orf83, FLJ32112" ENSG00000116205 "Transcription elongation factor A N-terminal and central domain containing 2" Q96MN5 1 54053584-54112519 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 58.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046918 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 6: Non-specific - Immune response" "Cluster 37: Non-specific - mRNA processing" "Cluster 3: Early primary spermatocytes - Early meiosis" 4 Nucleoplasm Vesicles "HPA046918: " "unprognostic (3.31e-2)" "unprognostic (1.21e-1)" "unprognostic (9.53e-2)" "unprognostic (6.30e-3)" "unprognostic (3.35e-2)" "unprognostic (1.25e-1)" "unprognostic (2.09e-1)" "unprognostic (3.61e-2)" "potential prognostic unfavorable (9.39e-5)" "unprognostic (2.93e-2)" "unprognostic (4.52e-1)" "unprognostic (3.24e-3)" "potential prognostic unfavorable (7.78e-5)" "unprognostic (8.80e-3)" "unprognostic (1.75e-1)" "unprognostic (3.06e-1)" "unprognostic (1.57e-1)" "unprognostic (1.83e-1)" "unprognostic (1.49e-1)" "unprognostic (2.66e-1)" "unprognostic (6.88e-2)" "unprognostic (3.46e-1)" "unprognostic (7.64e-3)" "potential prognostic favorable (4.60e-4)" "unprognostic (3.00e-1)" "unprognostic (8.10e-3)" "unprognostic (5.44e-2)" "unprognostic (2.89e-1)" "unprognostic (3.55e-2)" "unprognostic (3.04e-1)" TCERG1 "CA150, TAF2S, Urn1" ENSG00000113649 "Transcription elongation regulator 1" O14776 5 146447311-146511961 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064854, HPA069752, HPA069808" Supported Enhanced Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 49: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 17: Non-specific - RNA processing" 54 Nucleoplasm "HPA064854: , HPA069752: , HPA069808: " "unprognostic (1.66e-1)" "unprognostic (1.11e-1)" "unprognostic (2.10e-1)" "unprognostic (3.07e-3)" "unprognostic (6.50e-2)" "unprognostic (1.78e-1)" "unprognostic (1.78e-1)" "unprognostic (9.33e-3)" "unprognostic (1.99e-1)" "unprognostic (8.19e-3)" "unprognostic (4.42e-3)" "unprognostic (2.47e-1)" "unprognostic (1.66e-2)" "potential prognostic unfavorable (1.62e-4)" "unprognostic (7.89e-2)" "unprognostic (1.63e-2)" "potential prognostic unfavorable (1.21e-4)" "unprognostic (1.16e-1)" "unprognostic (3.87e-2)" "unprognostic (1.09e-1)" "unprognostic (4.52e-1)" "potential prognostic unfavorable (4.64e-5)" "unprognostic (1.48e-2)" "unprognostic (8.80e-3)" "unprognostic (8.43e-2)" "unprognostic (1.62e-2)" "unprognostic (1.57e-1)" "unprognostic (1.72e-1)" "unprognostic (1.28e-1)" "unprognostic (8.17e-3)" "unprognostic (4.96e-3)" TCERG1L FLJ38950 ENSG00000176769 "Transcription elongation regulator 1 like" Q5VWI1 10 131092391-131311721 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 7.3;retina: 5.7;thyroid gland: 14.0" "Cell type enriched" "Detected in many" 5 "Retinal horizontal cells: 665.1" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 246.9;hippocampal CA1-3: 178.8;miscellaneous: 182.1" "Cancer enriched" "Detected in some" 16 "Thyroid Carcinoma (TCGA): 59.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 6.3;prostate cancer: 3.3" "Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA030816 Approved Nucleoplasm,Cytosol NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 11: Neuronal - Sensory perception" "Cluster 109: Neurons - Neuronal signaling" Nucleoplasm Cytosol "HPA030816: " "unprognostic (5.52e-3)" "unprognostic (4.94e-1)" "unprognostic (1.92e-1)" "unprognostic (4.93e-2)" TCF12 "bHLHb20, HEB, HsT17266, HTF4, p64" ENSG00000140262 "Transcription factor 12" Q99081 15 56918623-57299281 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Craniosynostosis, Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 2034.9" "Cell type enhanced" "Detected in all" "oligodendrocyte: 2436.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Spleen - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004432, HPA065827" Approved Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 80: Thymus - Adaptive immune response" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 80: Oligodendrocytes - Myelination" 69 "Nucleoplasm, Nuclear speckles" "CAB004432: , HPA065827: " "potential prognostic favorable (7.82e-4)" "unprognostic (7.73e-2)" "unprognostic (1.47e-1)" "unprognostic (3.42e-3)" "unprognostic (2.28e-1)" "unprognostic (2.02e-1)" "unprognostic (2.69e-3)" "unprognostic (2.36e-2)" "unprognostic (6.62e-2)" "unprognostic (1.44e-3)" "unprognostic (1.06e-2)" "unprognostic (5.20e-2)" "unprognostic (8.43e-2)" "unprognostic (6.66e-2)" "unprognostic (2.98e-2)" "unprognostic (1.84e-1)" "unprognostic (8.42e-2)" "unprognostic (5.62e-2)" "unprognostic (3.28e-1)" "unprognostic (4.51e-2)" "unprognostic (5.28e-2)" "unprognostic (5.14e-2)" "unprognostic (8.19e-2)" "unprognostic (1.91e-2)" "unprognostic (6.17e-2)" "unprognostic (3.66e-1)" "unprognostic (3.55e-3)" "unprognostic (3.84e-1)" "unprognostic (2.85e-1)" "unprognostic (3.61e-2)" "unprognostic (1.37e-1)" TCF15 "bHLHa40, EC2, PARAXIS" ENSG00000125878 "Transcription factor 15" Q12870 20 604257-610309 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 44.2;skeletal muscle: 19.6;tongue: 14.1" "Cell type enhanced" "Detected in some" "Late primary spermatocytes: 4.3;Lymphatic endothelial cells: 3.9;Megakaryocytes: 6.2;Pericytes: 19.1;Vascular endothelial cells: 30.5;Vascular smooth muscle cells: 16.6" "Group enriched" "Detected in some" 5 "endothelial cell: 14.0;pericyte: 19.1;vascular associated smooth muscle cell: 26.6" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 4.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "testis cancer: 4.5" "Adipose visceral - Endothelial cells, Liver - Vascular endothelial cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA050998, HPA060221" Approved Supported "Nuclear speckles" NA NA "Cluster 41: Striated muscle - Muscle contraction" "Cluster 47: Endothelial cells - Vasculature" "Cluster 49: HMC-1 - Innate immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "Nuclear speckles" "HPA050998: , HPA060221: " "unprognostic (9.54e-2)" "unprognostic (1.61e-1)" "potential prognostic favorable (1.31e-4)" "unprognostic (6.08e-2)" "unprognostic (1.50e-1)" "unprognostic (3.59e-1)" "potential prognostic unfavorable (2.67e-4)" "unprognostic (1.34e-1)" "unprognostic (4.31e-1)" "unprognostic (2.20e-1)" TCF19 SC1 ENSG00000137310 "Transcription factor 19" Q9Y242 6 31158331-31167159 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 2.0;Distal convoluted tubule cells: 3.1;Endometrial glandular cells: 2.1;Endometrial luminal cells: 2.7;Loop of henle epithelial cells: 6.2;Microglia: 2.5;Monocyte progenitors: 2.1;Paneth cells: 3.9;Papillary tip epithelial cells: 5.3;Renal collecting duct principal cells: 5.0;Renal connecting tubule cells: 3.0" "Cell type enhanced" "Detected in many" "leukocyte: 5.7;upper rhombic lip: 7.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA047093 Approved Nucleoplasm,Nucleoli NA Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 25: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 105: Non-specific - Mixed function" 16 "Nucleoplasm, Nucleoli" "HPA047093: " "unprognostic (1.45e-1)" "unprognostic (3.29e-2)" "unprognostic (2.43e-1)" "unprognostic (8.58e-2)" "unprognostic (3.51e-2)" "unprognostic (1.31e-1)" "unprognostic (1.25e-1)" "unprognostic (2.27e-1)" "unprognostic (3.18e-2)" "unprognostic (1.49e-1)" "unprognostic (1.85e-1)" "unprognostic (9.91e-2)" "unprognostic (4.60e-2)" "potential prognostic unfavorable (9.29e-6)" "unprognostic (1.28e-1)" "unprognostic (2.13e-2)" "unprognostic (2.04e-1)" "unprognostic (2.28e-1)" "unprognostic (5.72e-2)" "unprognostic (4.31e-2)" "unprognostic (1.97e-2)" "unprognostic (5.27e-2)" "unprognostic (1.12e-1)" "unprognostic (3.79e-2)" "unprognostic (1.35e-1)" "unprognostic (1.02e-1)" "unprognostic (3.04e-1)" "unprognostic (1.91e-1)" "unprognostic (1.37e-1)" "unprognostic (2.62e-2)" TCF20 "AR1, SPBP" ENSG00000100207 "Transcription factor 20" Q9UGU0 22 42160013-42343616 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 101.4;Brain inhibitory neurons: 134.1;Cone photoreceptor cells: 101.4;Early spermatids: 97.7;Oligodendrocytes: 100.6;Other brain neurons: 149.1;Proximal tubule cells: 126.6;Renal collecting duct intercalated cells: 107.0;Renal connecting tubule cells: 102.8;Retinal bipolar cells: 109.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017849, HPA036786" Approved Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 68: Non-specific - Basic cellular processes" "Cluster 51: Neurons - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 102: Non-specific - Mixed function" 18 Nucleoplasm "Nuclear bodies" "CAB017849: , HPA036786: " "unprognostic (3.20e-1)" "unprognostic (3.49e-1)" "unprognostic (9.73e-3)" "unprognostic (8.69e-2)" "unprognostic (1.24e-1)" "unprognostic (1.03e-1)" "unprognostic (4.97e-3)" "unprognostic (5.37e-2)" "unprognostic (1.17e-2)" "potential prognostic favorable (1.22e-5)" "unprognostic (3.39e-3)" "unprognostic (2.45e-1)" "unprognostic (3.41e-2)" "unprognostic (1.05e-1)" "unprognostic (5.72e-2)" "unprognostic (2.02e-1)" "unprognostic (5.57e-2)" "unprognostic (8.55e-3)" "unprognostic (2.25e-1)" "unprognostic (7.64e-2)" "unprognostic (1.08e-1)" "unprognostic (3.19e-1)" "unprognostic (2.69e-2)" "potential prognostic favorable (2.51e-4)" "unprognostic (9.83e-2)" "unprognostic (1.22e-3)" "unprognostic (1.95e-1)" "unprognostic (7.76e-2)" "unprognostic (9.40e-2)" TCF21 "bHLHa23, POD1" ENSG00000118526 "Transcription factor 21" O43680 6 133889113-133895553 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 197.6;ovary: 192.4" "Cell type enhanced" "Detected in some" "Fibroblasts: 92.6;Leydig cells: 75.2;Ovarian stromal cells: 241.4;Pericytes: 70.9;Peritubular myoid cells: 108.2;Podocytes: 124.7;Smooth muscle cells: 56.0;Vascular smooth muscle cells: 25.1" "Cell type enhanced" "Detected in some" "fibroblast: 6.0;hippocampal dentate gyrus: 3.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "Bone cancer: 13.1;liver cancer: 10.9;Rhabdoid: 39.4" "Adrenal gland - Fibroblasts, Breast - Endothelial cells, Liver - Hepatic stellate cells, Lung - Fibroblasts_1, Pituitary gland - Fibroblasts, Prostate - Fibroblasts, Spleen - Fibroblasts_1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA013189, HPA025769" Uncertain Supported Nucleoplasm NA NA "Cluster 75: Ovary - Mixed function" "Cluster 29: Forebrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 6 Nucleoplasm "HPA013189: , HPA025769: " "unprognostic (1.93e-2)" "potential prognostic unfavorable (3.84e-4)" "unprognostic (1.54e-2)" "unprognostic (3.06e-1)" "unprognostic (1.42e-1)" "unprognostic (8.75e-2)" "potential prognostic favorable (6.28e-4)" "unprognostic (1.61e-2)" "unprognostic (4.49e-2)" "potential prognostic favorable (1.21e-4)" "unprognostic (1.05e-2)" "unprognostic (2.36e-3)" "unprognostic (3.40e-2)" "potential prognostic unfavorable (8.20e-5)" "unprognostic (6.37e-2)" "unprognostic (7.79e-2)" "unprognostic (2.52e-1)" "unprognostic (1.77e-1)" "unprognostic (3.67e-2)" "unprognostic (4.28e-2)" "unprognostic (1.93e-1)" "unprognostic (6.88e-2)" "unprognostic (1.44e-2)" "unprognostic (8.63e-2)" "unprognostic (4.35e-2)" TCF23 "bHLHa24, OUT" ENSG00000163792 "Transcription factor 23" Q7RTU1 2 27149004-27156974 "Predicted intracellular proteins, Transcription factors" "Differentiation, Myogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "cervix: 14.3;endometrium 1: 45.1;fallopian tube: 30.0;ovary: 18.4;smooth muscle: 19.0" "Cell type enhanced" "Detected in some" "Breast lactating cells: 3.9;Cardiomyocytes: 6.6;Leydig cells: 11.9;Ocular epithelial cells: 4.6;Ovarian stromal cells: 12.2;Pericytes: 3.8;Peritubular myoid cells: 29.3;Smooth muscle cells: 18.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.5" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.5" "Not detected" "Not detected" "Lung - Fibroblasts_2, Spleen - Fibroblasts_1" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA044596 Approved "Nuclear speckles" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 75: Ovary - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 94: Gonadal somatic cells - Mixed function" 4 "Nuclear speckles" "HPA044596: " "unprognostic (2.56e-3)" "unprognostic (9.87e-3)" "unprognostic (2.86e-1)" "unprognostic (3.21e-2)" TCF24 bHLHa25 ENSG00000261787 "Transcription factor 24" Q7RTU0 8 66946501-66962591 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 1.0;testis: 1.4" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 72.1;Distal convoluted tubule cells: 65.3" "Cell type enriched" "Detected in some" 9 "ependymal cell: 14.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Testis - Spermatocytes, Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 46: Brainstem - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 1 "unprognostic (2.18e-1)" TCF25 "KIAA1049, Nulp1" ENSG00000141002 "Transcription factor 25" Q9BQ70 16 89873570-89913627 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041699, HPA041786" Enhanced NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 24: Non-specific - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 22 "HPA041699: , HPA041786: " "unprognostic (2.40e-1)" "unprognostic (3.37e-1)" "unprognostic (8.36e-2)" "unprognostic (6.45e-2)" "unprognostic (6.93e-2)" "unprognostic (2.15e-1)" "unprognostic (6.47e-2)" "potential prognostic favorable (8.02e-4)" "unprognostic (2.39e-1)" "unprognostic (3.70e-2)" "potential prognostic favorable (3.51e-5)" "unprognostic (2.11e-1)" "potential prognostic favorable (9.05e-6)" "unprognostic (1.95e-2)" "unprognostic (6.06e-2)" "unprognostic (2.21e-1)" "unprognostic (3.37e-2)" "unprognostic (2.64e-2)" "unprognostic (3.44e-1)" "unprognostic (7.17e-2)" "unprognostic (6.42e-2)" "unprognostic (8.43e-2)" "unprognostic (1.36e-1)" "unprognostic (1.22e-1)" "unprognostic (1.34e-1)" "unprognostic (3.60e-1)" "unprognostic (2.84e-1)" "unprognostic (1.31e-1)" "unprognostic (1.29e-1)" "unprognostic (2.93e-2)" "potential prognostic favorable (4.79e-4)" TCF3 "bHLHb21, E2A, E47, ITF1, MGC129647, MGC129648, p75, VDIR" ENSG00000071564 "Transcription factor 3" P15923 19 1609291-1652615 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 128.5;Plasma cells: 96.0;Undifferentiated spermatogonia: 119.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Liver - Vascular endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018351, HPA049808, HPA062476" Approved Enhanced Nucleoplasm No No "Cluster 17: B-cells - Immunoglobulins" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 7: Non-specific - Ribosome" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 48 Nucleoplasm "CAB018351: , HPA049808: , HPA062476: " "unprognostic (1.46e-2)" "unprognostic (5.15e-2)" "unprognostic (5.11e-1)" "unprognostic (2.48e-3)" "unprognostic (3.57e-1)" "unprognostic (5.16e-2)" "unprognostic (2.23e-2)" "unprognostic (9.37e-3)" "unprognostic (4.99e-2)" "unprognostic (1.23e-3)" "potential prognostic unfavorable (6.60e-5)" "unprognostic (6.19e-2)" "unprognostic (1.10e-2)" "potential prognostic unfavorable (1.01e-4)" "unprognostic (2.92e-2)" "unprognostic (1.81e-1)" "unprognostic (1.24e-3)" "unprognostic (7.72e-2)" "unprognostic (4.70e-3)" "unprognostic (2.89e-1)" "unprognostic (8.32e-2)" "unprognostic (1.43e-1)" "unprognostic (1.38e-3)" "unprognostic (9.58e-3)" "unprognostic (5.65e-2)" "unprognostic (7.06e-3)" "unprognostic (1.40e-1)" "unprognostic (3.95e-2)" "unprognostic (1.75e-1)" "unprognostic (2.42e-1)" "potential prognostic favorable (3.90e-4)" TCF4 "bHLHb19, E2-2, ITF2, SEF2-1B" ENSG00000196628 "Transcription factor 4" P15884 18 55222185-55664787 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, DNA-binding" "Corneal dystrophy, Disease variant, Epilepsy, Intellectual disability, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibro-adipogenic progenitors: 1090.9;Oligodendrocyte progenitor cells: 1148.0;pDCs: 2703.9;Vascular endothelial cells: 1659.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 14 "memory B-cell: 174.1;naive B-cell: 147.6;plasmacytoid DC: 560.8" "Group enriched" "Detected in many" 33 "B-cells: 174.1;dendritic cells: 560.8" "Cancer enhanced" "Detected in all" "Neuroblastoma: 66.6" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020722, HPA025958" Approved Supported Nucleoplasm,Cytosol "Secreted - unknown location" Transcription NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 61: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 191 "Nucleoplasm, Cytosol" "CAB020722: , HPA025958: " "unprognostic (2.61e-2)" "unprognostic (6.41e-2)" "unprognostic (7.41e-3)" "unprognostic (5.76e-3)" "unprognostic (2.68e-1)" "unprognostic (1.28e-1)" "unprognostic (1.87e-1)" "unprognostic (2.02e-2)" "unprognostic (2.03e-2)" "unprognostic (2.94e-3)" "validated prognostic favorable (3.28e-7)" "validated prognostic favorable (4.79e-6)" "unprognostic (1.46e-1)" "unprognostic (3.86e-2)" "unprognostic (2.36e-2)" "unprognostic (7.40e-2)" "unprognostic (2.35e-1)" "unprognostic (1.09e-2)" "unprognostic (7.80e-2)" "unprognostic (3.48e-3)" "unprognostic (9.78e-2)" "unprognostic (1.08e-1)" "unprognostic (9.92e-2)" "unprognostic (1.15e-1)" "unprognostic (1.48e-2)" "unprognostic (9.04e-3)" "unprognostic (4.39e-2)" "unprognostic (2.78e-1)" "unprognostic (2.85e-3)" "unprognostic (2.10e-1)" TCF7 TCF-1 ENSG00000081059 "Transcription factor 7" P36402 5 134114681-134151865 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "lymphoid tissue: 518.8" "Cell type enhanced" "Detected in many" "Epicardial cells: 186.5;Fallopian tube ciliated cells: 165.4;Innate lymphoid cells: 203.7;T-cells: 125.9;Thymocytes: 146.5" "Group enriched" "Detected in all" 4 "choroid plexus epithelial cell: 54.4;ependymal cell: 49.5;leukocyte: 89.1" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "choroid plexus: 44.7" "Group enriched" "Detected in many" 4 "MAIT T-cell: 28.6;memory CD4 T-cell: 49.9;memory CD8 T-cell: 29.2;naive CD4 T-cell: 97.5;naive CD8 T-cell: 61.9;NK-cell: 43.1" "Group enriched" "Detected in many" 20 "NK-cells: 43.1;T-cells: 97.5" "Cancer enhanced" "Detected in all" "Leukemia: 105.8" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Colon - Enteric glia cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Prostate - T-cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019403, HPA058863, HPA070505" Enhanced Enhanced Nucleoplasm NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 80: Thymus - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" 6 Nucleoplasm "CAB019403: , HPA058863: , HPA070505: " "unprognostic (5.13e-2)" "unprognostic (7.28e-3)" "unprognostic (4.15e-2)" "unprognostic (2.20e-1)" "unprognostic (8.49e-2)" "unprognostic (1.25e-1)" "unprognostic (5.54e-2)" "unprognostic (7.26e-3)" "unprognostic (2.32e-2)" "unprognostic (1.10e-1)" "unprognostic (1.35e-1)" "unprognostic (1.60e-1)" "unprognostic (5.10e-1)" "unprognostic (1.14e-1)" "unprognostic (6.39e-2)" "unprognostic (1.75e-1)" "unprognostic (2.73e-1)" "unprognostic (2.84e-2)" "unprognostic (3.03e-1)" "unprognostic (2.20e-1)" "unprognostic (3.69e-2)" "unprognostic (1.65e-1)" "unprognostic (5.46e-2)" "unprognostic (1.16e-1)" "unprognostic (1.07e-1)" "unprognostic (3.80e-1)" "unprognostic (3.47e-1)" "unprognostic (3.67e-2)" "unprognostic (1.43e-1)" "unprognostic (2.20e-1)" "unprognostic (3.23e-2)" TCF7L1 TCF3 ENSG00000152284 "Transcription factor 7 like 1" Q9HCS4 2 85133392-85310387 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 429.7;Bergmann glia: 251.8;Fibro-adipogenic progenitors: 362.6;Pituitary stem cells: 295.6;Podocytes: 593.9;Renal collecting duct principal cells: 432.9" "Group enriched" "Detected in many" 4 "astrocyte: 241.7;Bergmann glia: 254.9;choroid plexus epithelial cell: 153.1;committed oligodendrocyte precursor: 68.1;endothelial cell: 173.3;ependymal cell: 175.9;fibroblast: 216.8;pericyte: 179.3;vascular associated smooth muscle cell: 192.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 5.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071298 Supported Nucleoplasm,Cytosol NA NA "Cluster 32: Basophils - Transcription" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 19: Astrocytes - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 1 Nucleoplasm Cytosol "HPA071298: " "unprognostic (2.69e-1)" "unprognostic (2.50e-1)" "unprognostic (2.41e-2)" "unprognostic (3.33e-2)" "unprognostic (2.73e-2)" "unprognostic (2.71e-2)" "unprognostic (6.33e-2)" "unprognostic (4.67e-2)" "unprognostic (1.30e-1)" "unprognostic (3.80e-2)" "potential prognostic favorable (4.78e-4)" "unprognostic (9.06e-3)" "unprognostic (5.63e-3)" "potential prognostic unfavorable (7.79e-5)" "unprognostic (1.01e-2)" "unprognostic (6.78e-2)" "unprognostic (1.96e-1)" "unprognostic (1.41e-1)" "unprognostic (5.04e-2)" "unprognostic (1.77e-1)" "unprognostic (2.29e-1)" "unprognostic (1.37e-2)" "unprognostic (2.30e-2)" "unprognostic (1.32e-1)" "unprognostic (1.60e-1)" "unprognostic (1.13e-2)" "unprognostic (1.13e-2)" "unprognostic (1.42e-3)" "unprognostic (1.97e-1)" "unprognostic (3.95e-2)" "unprognostic (1.94e-1)" TCF7L2 "TCF-4, TCF4" ENSG00000148737 "Transcription factor 7 like 2" Q9NQB0 10 112950247-113167678 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, DNA-binding, Repressor" "Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 890.0;Extravillous trophoblasts: 978.6;Foveolar cells: 1101.0;Kupffer cells: 1068.0" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 873.4;thalamic excitatory: 827.1" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "thalamus: 379.6" "Group enriched" "Detected in many" 7 "intermediate monocyte: 24.2;non-classical monocyte: 61.8" "Lineage enriched" "Detected in many" 11 "monocytes: 61.8" "Low cancer specificity" "Detected in all" "Pancreas - Endothelial cells, Spleen - Macrophages" "Group enriched" "Detected in all" 9 "midbrain: 67.2;thalamus: 86.6" "Group enriched" "Detected in all" 4 "midbrain: 194.2;pons: 127.6;thalamus: 215.0" "CAB013535, HPA038800" Supported Supported "Nucleoplasm,Nuclear bodies,Cytosol" Yes No "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 47 Nucleoplasm "Nuclear bodies, Cytosol" "CAB013535: , HPA038800: " "potential prognostic favorable (6.22e-4)" "unprognostic (3.34e-2)" "unprognostic (8.87e-2)" "unprognostic (3.62e-2)" "unprognostic (3.36e-1)" "unprognostic (7.42e-2)" "unprognostic (3.11e-2)" "unprognostic (1.02e-1)" "unprognostic (2.87e-1)" "unprognostic (1.50e-1)" "validated prognostic favorable (9.23e-8)" "validated prognostic favorable (2.72e-5)" "unprognostic (2.81e-1)" "unprognostic (2.05e-1)" "unprognostic (8.66e-3)" "unprognostic (1.08e-1)" "unprognostic (5.46e-3)" "unprognostic (8.78e-2)" "unprognostic (2.26e-1)" "unprognostic (5.86e-2)" "unprognostic (1.39e-1)" "unprognostic (5.43e-3)" "unprognostic (1.77e-2)" "unprognostic (6.38e-3)" "unprognostic (3.33e-1)" "unprognostic (3.85e-1)" "unprognostic (1.19e-1)" "unprognostic (2.99e-1)" "unprognostic (1.72e-1)" "unprognostic (1.42e-1)" "unprognostic (7.01e-2)" TCFL5 "bHLHe82, CHA, E2BP-1, Figlb" ENSG00000101190 "Transcription factor like 5" Q9UL49 20 62841005-62861822 "Predicted intracellular proteins, Transcription factors" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 65.8;testis: 69.2" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 82.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA055223, HPA076419" Enhanced Supported Nucleoplasm NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 1 Nucleoplasm "HPA055223: , HPA076419: " "unprognostic (3.25e-1)" "unprognostic (8.42e-3)" "unprognostic (6.49e-2)" "unprognostic (5.15e-1)" "unprognostic (1.18e-1)" "unprognostic (6.77e-2)" "unprognostic (1.99e-1)" "unprognostic (7.05e-3)" "unprognostic (7.86e-3)" "potential prognostic unfavorable (2.65e-4)" "unprognostic (2.22e-1)" "unprognostic (4.59e-2)" "unprognostic (1.87e-1)" "unprognostic (2.15e-2)" "unprognostic (3.01e-3)" "unprognostic (4.97e-1)" "unprognostic (2.24e-1)" "unprognostic (4.79e-2)" "unprognostic (2.24e-1)" "unprognostic (1.68e-1)" "unprognostic (1.33e-1)" "unprognostic (1.75e-1)" "unprognostic (3.05e-2)" "unprognostic (3.20e-1)" "unprognostic (8.27e-3)" "unprognostic (4.25e-2)" "unprognostic (1.71e-1)" "unprognostic (8.36e-2)" "unprognostic (1.78e-1)" "potential prognostic unfavorable (3.13e-4)" "unprognostic (2.68e-1)" TCHH THH ENSG00000159450 Trichohyalin Q07283 1 152106317-152115444 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "skin 1: 37.1" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 13.2;Early primary spermatocytes: 43.8;Extravillous trophoblasts: 10.8;Kupffer cells: 72.8;Lymphatic endothelial cells: 11.8;Macrophages: 28.4;monocytes: 23.2;Respiratory deuterosomal cells: 28.0;Salivary acinar cells: 19.9;Suprabasal keratinocytes: 48.1" "Cell type enhanced" "Detected in some" "mammillary body: 1.8;splatter: 1.6" "Cancer enhanced" "Detected in some" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 4.6;Head and Neck Squamous Cell Carcinoma (TCGA): 3.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "head and neck cancer: 3.0" "Adipose subcutaneous - Macrophages, Colon - Macrophages, Skin - Inner root sheath cells, Spleen - Macrophages" "Low region specificity" "Detected in many" HPA028375 Approved NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 2 "HPA028375: " "unprognostic (1.63e-2)" "unprognostic (3.16e-1)" "unprognostic (1.44e-2)" "unprognostic (1.76e-1)" "unprognostic (3.68e-1)" TCHHL1 "S100A17, THHL1" ENSG00000182898 "Trichohyalin like 1" Q5QJ38 1 152084141-152089064 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "cervical cancer: 5.3;Gastric cancer: 1.8" "Skin - Hair cortex cells, Skin - Inner root sheath cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA042579, HPA063483" Enhanced Approved "Nuclear membrane,Nucleoli" NA NA "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 82: Dendritic cells - Antigen presentation" 1 "Nuclear membrane, Nucleoli" "HPA042579: , HPA063483: " TCHP "MGC10854, TpMs" ENSG00000139437 "Trichoplein keratin filament binding" Q9BT92 12 109900264-109983841 "Predicted intracellular proteins" "Apoptosis, Cilium biogenesis/degradation" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 253.5;Epicardial cells: 177.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA038638, HPA061543" Supported Approved "Plasma membrane,Primary cilium,Centrosome,Basal body,Cytosol,Mid piece,Principal piece" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 2: Non-specific - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 38: Non-specific - Transcription" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 63 "Plasma membrane, Cytosol" "Primary cilium, Centrosome, Basal body, Mid piece, Principal piece" "HPA038638: , HPA061543: " "unprognostic (1.29e-1)" "unprognostic (8.47e-2)" "unprognostic (2.29e-1)" "unprognostic (1.51e-1)" "unprognostic (2.22e-1)" "unprognostic (8.00e-2)" "unprognostic (1.79e-1)" "unprognostic (9.22e-2)" "unprognostic (6.43e-2)" "unprognostic (9.25e-2)" "unprognostic (1.12e-2)" "unprognostic (6.48e-2)" "unprognostic (1.68e-1)" "unprognostic (1.02e-3)" "unprognostic (3.34e-2)" "unprognostic (1.23e-1)" "unprognostic (3.36e-1)" "unprognostic (2.01e-1)" "unprognostic (3.07e-2)" "unprognostic (1.15e-1)" "unprognostic (3.62e-1)" "unprognostic (9.11e-3)" "unprognostic (2.85e-1)" "unprognostic (1.55e-1)" "unprognostic (8.42e-2)" "unprognostic (2.42e-1)" "unprognostic (3.31e-2)" "unprognostic (2.65e-2)" "unprognostic (1.78e-1)" "unprognostic (1.35e-1)" "unprognostic (1.44e-1)" TCIM "C8orf4, hTC-1, TC-1, TC1" ENSG00000176907 "Transcriptional and immune response regulator" Q9NR00 8 40153482-40155310 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 771.2;Breast hormone-responsive cells: 289.7;Endometrial glandular cells: 662.7;Epididymal basal cells: 387.5;Epididymal clear cells: 326.6;Foveolar cells: 263.0;Pancreatic acinar cells: 331.1;Pericytes: 274.4;Prostatic club cells: 453.1;Salivary acinar cells: 400.6;Schwann cells: 435.6;Transitional alveolar cells: 422.5;Urothelial cells: 350.6" "Cell type enhanced" "Detected in many" "CGE interneuron: 27.8;endothelial cell: 47.8;LAMP5-LHX6 and Chandelier: 36.6;MGE interneuron: 32.8" "Cancer enhanced" "Detected in all" "Lung Adenocarcinoma (TCGA): 250.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 59.5" "Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027188 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 23: Choroid plexus - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 51: Secretory epithelial cells - Mixed function" 1 Nucleoplasm "Plasma membrane, Cytosol" "HPA027188: " "unprognostic (1.60e-2)" "unprognostic (2.69e-1)" "unprognostic (2.73e-1)" "potential prognostic favorable (1.92e-5)" "unprognostic (1.32e-1)" "potential prognostic unfavorable (4.81e-5)" "unprognostic (7.14e-2)" "unprognostic (8.60e-3)" "unprognostic (1.76e-2)" "validated prognostic favorable (1.17e-4)" "validated prognostic favorable (1.55e-4)" "unprognostic (3.02e-1)" "unprognostic (1.49e-1)" "unprognostic (1.79e-2)" "unprognostic (1.13e-1)" "unprognostic (2.03e-2)" "unprognostic (4.50e-1)" "unprognostic (6.22e-2)" "unprognostic (1.93e-2)" "unprognostic (7.97e-2)" "unprognostic (1.79e-1)" "unprognostic (1.68e-1)" "unprognostic (6.73e-2)" "unprognostic (2.88e-3)" "unprognostic (1.42e-2)" "unprognostic (4.73e-3)" "unprognostic (3.81e-1)" "unprognostic (1.11e-2)" "unprognostic (1.23e-1)" TCIRG1 "a3, Atp6i, ATP6N1C, ATP6V0A3, OC-116, OC116, TIRC7" ENSG00000110719 "T cell immune regulator 1, ATPase H+ transporting V0 subunit a3" Q13488 11 68039025-68050895 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrogen ion transport, Ion transport, Transport" "Disease variant, Osteopetrosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 278.3" "Cell type enhanced" "Detected in many" "Foveolar cells: 116.7;Kupffer cells: 113.8;monocytes: 135.2;Neutrophils: 169.0" "Group enriched" "Detected in many" 10 "central nervous system macrophage: 25.6;endothelial cell: 19.0;fibroblast: 15.4;leukocyte: 44.5;pericyte: 20.7;vascular associated smooth muscle cell: 12.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038742 Approved Approved Mitochondria NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 70: Non-specific - Protein processing" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 27 Mitochondria "HPA038742: " "unprognostic (1.66e-1)" "unprognostic (1.33e-2)" "unprognostic (2.73e-2)" "unprognostic (1.81e-1)" "unprognostic (2.42e-1)" "unprognostic (3.29e-2)" "unprognostic (3.18e-3)" "unprognostic (3.36e-2)" "unprognostic (3.99e-2)" "unprognostic (1.70e-1)" "potential prognostic unfavorable (2.40e-6)" "unprognostic (7.81e-2)" "unprognostic (6.12e-3)" "unprognostic (2.85e-1)" "unprognostic (7.89e-2)" "unprognostic (2.78e-1)" "unprognostic (1.89e-3)" "unprognostic (7.00e-2)" "unprognostic (1.30e-1)" "unprognostic (1.72e-2)" "unprognostic (2.15e-3)" "unprognostic (5.20e-2)" "unprognostic (2.21e-2)" "unprognostic (1.39e-1)" "unprognostic (1.72e-2)" "unprognostic (2.80e-1)" "unprognostic (2.28e-1)" "unprognostic (3.25e-3)" "unprognostic (7.51e-3)" "unprognostic (6.34e-2)" "unprognostic (1.23e-3)" TCL1A TCL1 ENSG00000100721 "TCL1 family AKT coactivator A" P56279 14 95709947-95714196 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "lymphoid tissue: 249.5" "Cell type enriched" "Detected in some" 4 "pDCs: 735.5" "Cell type enriched" "Detected in single" 31 "leukocyte: 3.1" "Cancer enriched" "Detected in many" 21 "Testicular Germ Cell Tumor (TCGA): 189.5" "Not detected" "Not detected" "Group enriched" "Detected in many" 295 "memory B-cell: 879.8;naive B-cell: 2165.4;plasmacytoid DC: 1102.9" "Group enriched" "Detected in all" 348 "B-cells: 2165.4;dendritic cells: 1102.9" "Group enriched" "Detected in some" 187 "Leukemia: 214.5;lymphoma: 528.5" "Testis - Spermatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "CAB004045, HPA016604" Enhanced Enhanced "Nucleoplasm,Endoplasmic reticulum,Cytosol" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 50 "Endoplasmic reticulum, Cytosol" Nucleoplasm "CAB004045: , HPA016604: " "unprognostic (1.09e-1)" "unprognostic (1.86e-3)" "unprognostic (5.76e-3)" "unprognostic (3.65e-1)" "unprognostic (6.79e-2)" "potential prognostic favorable (6.88e-4)" "potential prognostic favorable (9.56e-4)" "unprognostic (1.21e-2)" "unprognostic (2.75e-2)" "unprognostic (3.00e-1)" "unprognostic (1.72e-1)" "unprognostic (2.60e-2)" "unprognostic (1.44e-1)" "unprognostic (2.27e-1)" "unprognostic (2.44e-1)" TCL1B TML1 ENSG00000213231 "TCL1 family AKT coactivator B" O95988 14 95686426-95692628 "Predicted intracellular proteins" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 1.1;lymphoid tissue: 2.3;testis: 2.5" "Group enriched" "Detected in some" 5 "Proximal tubule cells: 1.9;Syncytiotrophoblasts: 2.5" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 43 "Testicular Germ Cell Tumor (TCGA): 84.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 24 "naive B-cell: 11.8;plasmacytoid DC: 6.2" "Group enriched" "Detected in many" 24 "B-cells: 11.8;dendritic cells: 6.2" "Cancer enriched" "Detected in some" 6 "lymphoma: 105.6" "Kidney - Proximal tubular cells" "Not detected" "Not detected" HPA053163 Uncertain Approved Cytosol NA NA "Cluster 34: B-cells - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 11: White matter - Signal transduction" "Cluster 55: Lymphoma - Immune response" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." 14 Cytosol "HPA053163: " "unprognostic (8.01e-2)" "unprognostic (5.00e-1)" "unprognostic (2.09e-1)" "unprognostic (1.68e-1)" TCN1 "TC1, TCI" ENSG00000134827 "Transcobalamin 1" P20061 11 59852800-59866489 "Plasma proteins, Predicted secreted proteins" "Cobalt transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "salivary gland: 816.7" "Cell type enhanced" "Detected in some" "Endometrial glandular cells: 144.9;Endometrial secretory cells: 211.6;Esophageal apical cells: 259.2;Lacrimal acinar cells: 1406.7;Neutrophil progenitors: 343.8;Parietal cells: 744.3;Salivary acinar cells: 531.4;Salivary myoepithelial cells: 177.0;Submucosal glandular cells: 564.6" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Pancreatic Adenocarcinoma (TCGA): 193.4" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 149 "basophil: 2379.0" "Lineage enriched" "Detected in many" 1591 "granulocytes: 2379.0" "Cancer enhanced" "Detected in many" "Bile duct cancer: 62.4;breast cancer: 36.3;ovarian cancer: 40.4" "Lung - Neutrophils_1, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Urothelial cells, Spleen - Neutrophils_1" "Not detected" "Not detected" "Secreted to blood" Transport NA NA 3700000 "Cluster 46: Basophils - Proteolysis" "Cluster 82: Salivary gland - Secretion" "Cluster 66: Non-specific - Mitochondria" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 4 "unprognostic (2.39e-2)" "unprognostic (1.37e-3)" "unprognostic (1.21e-1)" "unprognostic (1.69e-1)" "unprognostic (3.44e-2)" "unprognostic (1.33e-1)" "unprognostic (2.31e-1)" "unprognostic (5.00e-3)" "potential prognostic unfavorable (2.23e-7)" "unprognostic (1.43e-2)" "potential prognostic unfavorable (1.21e-5)" "unprognostic (3.04e-2)" "potential prognostic unfavorable (1.17e-4)" "unprognostic (2.47e-3)" "unprognostic (1.55e-1)" "unprognostic (1.41e-1)" "unprognostic (5.16e-3)" "unprognostic (4.36e-1)" "unprognostic (2.47e-1)" "unprognostic (1.55e-1)" "unprognostic (3.93e-3)" "unprognostic (3.59e-2)" "unprognostic (2.47e-1)" "unprognostic (3.07e-1)" "unprognostic (1.23e-2)" TCN2 "D22S676, D22S750, TC2" ENSG00000185339 "Transcobalamin 2" P20062 22 30607003-30627271 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cobalt transport, Ion transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 108.1" "Group enriched" "Detected in many" 4 "Enterocytes: 531.2;Kupffer cells: 221.4" "Group enriched" "Detected in many" 6 "endothelial cell: 122.1;fibroblast: 36.5" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 162.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 43.3;intermediate monocyte: 66.4;non-classical monocyte: 23.9" "Lineage enriched" "Detected in many" 9 "monocytes: 66.4" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Lung - Macrophages, Minor Salivary Gland - Macrophages, Skin - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000837 Approved Cytosol "Secreted to blood" Transport NA NA 4800000 "Cluster 40: Monocytes - Innate immune response" "Cluster 72: Kidney - Transmembrane transport" "Cluster 47: Endothelial cells - Vasculature" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 1: Enterocytes - Absorption and Digestion" 4 Cytosol "HPA000837: " "unprognostic (2.08e-1)" "unprognostic (4.97e-2)" "unprognostic (1.05e-1)" "unprognostic (3.33e-3)" "unprognostic (2.45e-1)" "unprognostic (7.35e-2)" "unprognostic (2.35e-1)" "unprognostic (3.25e-2)" "unprognostic (2.60e-1)" "unprognostic (9.04e-3)" "validated prognostic favorable (8.31e-7)" "validated prognostic favorable (2.66e-5)" "unprognostic (3.24e-2)" "potential prognostic unfavorable (2.54e-5)" "unprognostic (2.57e-1)" "unprognostic (2.96e-2)" "unprognostic (2.50e-1)" "unprognostic (2.34e-1)" "unprognostic (1.60e-1)" "unprognostic (6.56e-2)" "unprognostic (1.29e-1)" "unprognostic (7.68e-2)" "unprognostic (3.03e-2)" "unprognostic (1.17e-1)" "unprognostic (1.69e-2)" "unprognostic (1.55e-1)" "unprognostic (5.38e-2)" "unprognostic (1.45e-3)" "unprognostic (2.42e-2)" "unprognostic (2.04e-1)" "unprognostic (2.16e-1)" TCOF1 "TCS, treacle" ENSG00000070814 "Treacle ribosome biogenesis factor 1" Q13428 5 150357629-150400308 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 111.1;cDC: 138.4;Oocytes: 161.2;pDCs: 109.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033199, HPA038237, HPA038238" Enhanced Enhanced "Nucleoli fibrillar center" NA NA 310000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 82: Dendritic cells - Antigen presentation" 34 "Nucleoli fibrillar center" "CAB033199: , HPA038237: , HPA038238: " "unprognostic (1.03e-1)" "unprognostic (4.49e-2)" "unprognostic (1.56e-1)" "unprognostic (8.98e-2)" "unprognostic (2.54e-1)" "unprognostic (1.81e-1)" "unprognostic (4.78e-2)" "unprognostic (7.13e-2)" "unprognostic (6.55e-2)" "unprognostic (1.52e-3)" "unprognostic (3.81e-2)" "unprognostic (6.39e-2)" "unprognostic (4.05e-2)" "validated prognostic unfavorable (6.41e-13)" "validated prognostic unfavorable (8.26e-4)" "unprognostic (2.01e-3)" "potential prognostic unfavorable (3.93e-5)" "unprognostic (7.03e-2)" "unprognostic (2.35e-1)" "unprognostic (1.94e-1)" "unprognostic (1.29e-1)" "unprognostic (2.43e-1)" "potential prognostic unfavorable (6.29e-4)" "potential prognostic unfavorable (4.85e-4)" "unprognostic (9.85e-2)" "unprognostic (9.89e-3)" "unprognostic (2.85e-1)" "unprognostic (2.22e-2)" "unprognostic (2.21e-1)" "unprognostic (3.11e-1)" "unprognostic (9.00e-2)" TCP1 "CCT1, Ccta, D6S230E" ENSG00000120438 "T-complex 1" P17987 6 159778498-159789703 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Chaperone, Hydrolase" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 525.6;Late spermatids: 1013.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017460, HPA027337, HPA031082" Approved NA NA 3700000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 75: Non-specific - Chaperones and protein folding" 195 "CAB017460: , HPA027337: , HPA031082: " "unprognostic (6.58e-3)" "potential prognostic unfavorable (8.80e-5)" "unprognostic (6.66e-2)" "unprognostic (1.73e-2)" "unprognostic (4.08e-2)" "unprognostic (1.35e-1)" "unprognostic (1.06e-1)" "unprognostic (5.19e-2)" "unprognostic (6.67e-3)" "potential prognostic unfavorable (8.60e-6)" "potential prognostic favorable (4.24e-5)" "unprognostic (1.88e-1)" "unprognostic (9.87e-3)" "validated prognostic unfavorable (7.13e-5)" "validated prognostic unfavorable (1.50e-5)" "unprognostic (1.71e-3)" "unprognostic (1.48e-3)" "unprognostic (4.27e-2)" "unprognostic (1.28e-1)" "unprognostic (3.35e-3)" "unprognostic (1.03e-1)" "unprognostic (8.49e-2)" "potential prognostic unfavorable (5.55e-4)" "unprognostic (6.38e-2)" "unprognostic (2.24e-2)" "unprognostic (3.79e-2)" "unprognostic (1.31e-1)" "unprognostic (3.04e-1)" "unprognostic (3.54e-1)" "unprognostic (2.31e-1)" "unprognostic (3.58e-1)" TCP10L PRED77 ENSG00000242220 "T-complex 10 like" Q8TDR4 21 32497967-32587373 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 142.6" "Cell type enhanced" "Detected in some" "Astrocytes: 50.5;Bergmann glia: 88.1;Brain excitatory neurons: 64.8;Brain inhibitory neurons: 66.0;Choroid plexus epithelial cells: 54.0;Early spermatids: 22.1;Ependymal cells: 141.2;Late spermatids: 30.9;Oligodendrocyte progenitor cells: 23.2;Oligodendrocytes: 42.8;Other brain neurons: 26.5" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in some" 7 "Liver Hepatocellular Carcinoma (TCGA): 7.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in single" 7 "basal ganglia: 1.1" HPA044709 Approved NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 22: Non-specific - Basic cellular functions" 35 "HPA044709: " "unprognostic (5.34e-2)" "unprognostic (2.40e-1)" "potential prognostic favorable (7.01e-4)" "unprognostic (1.30e-3)" "unprognostic (6.06e-3)" "unprognostic (2.68e-1)" "potential prognostic favorable (7.30e-4)" "unprognostic (2.80e-1)" "unprognostic (1.20e-1)" TCP11 "D6S230E, FPPR, KIAA0229" ENSG00000124678 "T-complex 11" Q8WWU5 6 35118071-35148610 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 346 "testis: 327.6" "Cell type enriched" "Detected in some" 5 "Late spermatids: 11780.0" "Low cell type specificity" "Detected in single" "Cancer enriched" "Detected in some" 4 "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 6.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA048311 Supported NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" "HPA048311: " "potential prognostic favorable (2.84e-4)" "potential prognostic favorable (1.73e-6)" "unprognostic (3.59e-1)" "unprognostic (3.15e-1)" TCP11L1 FLJ11336 ENSG00000176148 "T-complex 11 like 1" Q9NUJ3 11 33039417-33105943 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pituitary stem cells: 142.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005769 Approved Approved "Golgi apparatus,Cytosol" NA Yes "Cluster 10: Non-specific - Membrane trafficking" "Cluster 61: Non-specific - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 42 Cytosol "Golgi apparatus" "HPA005769: " "unprognostic (1.75e-1)" "unprognostic (4.00e-3)" "unprognostic (7.03e-2)" "unprognostic (1.70e-1)" "unprognostic (2.25e-1)" "unprognostic (4.47e-3)" "unprognostic (1.64e-1)" "unprognostic (2.68e-2)" "unprognostic (1.15e-1)" "unprognostic (2.11e-2)" "potential prognostic favorable (3.91e-6)" "unprognostic (3.19e-3)" "unprognostic (8.94e-2)" "unprognostic (1.09e-1)" "unprognostic (2.46e-1)" "unprognostic (1.81e-3)" "potential prognostic unfavorable (6.62e-4)" "unprognostic (8.95e-2)" "unprognostic (1.27e-1)" "unprognostic (6.68e-3)" "potential prognostic unfavorable (3.44e-4)" "unprognostic (2.67e-2)" "unprognostic (5.61e-2)" "unprognostic (1.01e-1)" "unprognostic (1.25e-1)" "unprognostic (1.26e-1)" "unprognostic (1.73e-1)" "unprognostic (8.77e-2)" "unprognostic (1.25e-1)" "unprognostic (5.70e-2)" "unprognostic (4.64e-2)" TCP11L2 MGC40368 ENSG00000166046 "T-complex 11 like 2" Q8N4U5 12 106301929-106347003 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 151.5;Choroid plexus epithelial cells: 191.6;Esophageal apical cells: 169.8;Neutrophil progenitors: 133.5;Neutrophils: 226.7;Oligodendrocytes: 121.7" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 160.6;oligodendrocyte: 164.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 67.3" "Lineage enriched" "Detected in all" 5 "granulocytes: 67.3" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Minor Salivary Gland - Mitotic cells (Minor salivary gland), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039483, HPA042188" Uncertain Supported "Nuclear speckles" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 24: Neutrophils - Innate immunity signal integration" 19 "Nuclear speckles" "HPA039483: , HPA042188: " "unprognostic (1.03e-1)" "unprognostic (4.58e-2)" "unprognostic (3.51e-1)" "unprognostic (7.62e-2)" "unprognostic (3.37e-1)" "unprognostic (3.12e-2)" "unprognostic (4.45e-2)" "unprognostic (2.87e-1)" "unprognostic (4.36e-2)" "unprognostic (1.34e-2)" "validated prognostic favorable (2.30e-7)" "validated prognostic favorable (8.39e-4)" "unprognostic (2.95e-1)" "unprognostic (3.84e-2)" "unprognostic (4.01e-1)" "unprognostic (3.88e-2)" "unprognostic (3.62e-2)" "unprognostic (7.28e-2)" "unprognostic (3.31e-1)" "unprognostic (7.19e-2)" "unprognostic (4.67e-2)" "unprognostic (5.36e-2)" "unprognostic (1.75e-1)" "unprognostic (1.04e-1)" "unprognostic (2.33e-2)" "unprognostic (1.22e-1)" "unprognostic (1.91e-1)" "unprognostic (2.66e-1)" "unprognostic (1.79e-1)" "unprognostic (4.20e-2)" "unprognostic (1.96e-1)" TCP11X1 ENSG00000268235 "T-complex 11 family, X-linked 1" X 102215298-102229532 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA048311 Uncertain NA NA "HPA048311: " TCP11X2 ENSG00000215029 "T-complex 11 family, X-linked 2" X 102456862-102471842 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells" HPA048311 Supported NA NA "HPA048311: " TCTA ENSG00000145022 "T cell leukemia translocation altered" P57738 3 49412212-49416476 "Disease related genes, Predicted membrane proteins" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 79.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007342 Approved Approved Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 76: Non-specific - Metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 65: Non-specific - Cell growth & division" 4 Cytosol "HPA007342: " "unprognostic (4.31e-2)" "unprognostic (3.32e-2)" "unprognostic (3.28e-2)" "unprognostic (3.67e-1)" "unprognostic (5.88e-3)" "unprognostic (1.47e-1)" "unprognostic (6.99e-3)" "potential prognostic unfavorable (4.71e-5)" "unprognostic (3.09e-1)" "unprognostic (2.88e-1)" "validated prognostic favorable (4.15e-8)" "validated prognostic favorable (6.85e-4)" "potential prognostic favorable (1.67e-7)" "unprognostic (7.23e-2)" "unprognostic (1.99e-1)" "unprognostic (1.94e-3)" "unprognostic (1.56e-1)" "unprognostic (1.90e-1)" "unprognostic (1.59e-1)" "unprognostic (3.01e-3)" "unprognostic (1.33e-1)" "unprognostic (1.20e-2)" "unprognostic (1.40e-1)" "unprognostic (2.71e-1)" "unprognostic (1.45e-1)" "unprognostic (2.19e-1)" "unprognostic (1.64e-2)" "unprognostic (7.42e-2)" "unprognostic (1.22e-1)" "unprognostic (3.90e-1)" "unprognostic (2.05e-1)" TCTE1 "D6S46, DRC5, FAP155, MGC33600" ENSG00000146221 "T-complex-associated-testis-expressed 1" Q5JU00 6 44278734-44297698 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 7.9;fallopian tube: 13.6;testis: 28.4" "Group enriched" "Detected in some" 4 "Early spermatids: 181.5;Late spermatids: 534.6" "Cell type enriched" "Detected in many" 6 "ependymal cell: 27.4" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Neuroblastoma: 2.6" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA031739 Approved "Vesicles,Cytosol,Mid piece" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 2: Neurons - Nucleosome" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" "Vesicles, Mid piece" Cytosol "HPA031739: " "unprognostic (1.41e-1)" "unprognostic (2.60e-1)" "unprognostic (2.25e-2)" TCTN1 "FLJ21127, JBTS13, TECT1" ENSG00000204852 "Tectonic family member 1" Q2MV58 12 110614027-110663431 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Developmental protein" "Ciliopathy, Joubert syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 31.9" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 149.2;Ependymal cells: 148.7;Epididymal efferent duct ciliated cells: 191.8;Fallopian tube ciliated cells: 304.4;Respiratory ciliated cells: 278.3" "Cell type enhanced" "Detected in all" "ependymal cell: 167.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039687, HPA040036" Approved Approved "Nucleoplasm,Actin filaments,Primary cilium" "Intracellular and membrane" "Developmental protein" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" 10 "Actin filaments, Primary cilium" Nucleoplasm "HPA039687: , HPA040036: " "unprognostic (2.21e-1)" "unprognostic (6.27e-2)" "unprognostic (2.09e-1)" "unprognostic (8.77e-2)" "unprognostic (1.35e-1)" "unprognostic (4.09e-2)" "unprognostic (2.14e-2)" "unprognostic (4.13e-3)" "unprognostic (1.28e-1)" "unprognostic (8.82e-3)" "unprognostic (2.71e-2)" "unprognostic (1.05e-1)" "unprognostic (5.67e-2)" "unprognostic (3.85e-2)" "unprognostic (1.87e-1)" "unprognostic (5.34e-2)" "unprognostic (6.74e-2)" "unprognostic (9.70e-3)" "unprognostic (1.91e-1)" "unprognostic (8.89e-2)" "unprognostic (1.83e-1)" "unprognostic (3.21e-1)" "unprognostic (3.09e-3)" "unprognostic (1.61e-1)" "unprognostic (1.51e-1)" "unprognostic (2.27e-1)" "unprognostic (1.84e-1)" "unprognostic (1.27e-2)" "unprognostic (8.36e-2)" "unprognostic (5.74e-2)" "unprognostic (6.48e-2)" TCTN2 "C12orf38, FLJ12975, JBTS24, MKS8, TECT2" ENSG00000168778 "Tectonic family member 2" Q96GX1 12 123671110-123708399 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Ciliopathy, Joubert syndrome, Meckel syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 37.2" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 49.6;Endometrial ciliated cells: 45.7;Ependymal cells: 72.4;Fallopian tube ciliated cells: 62.5;Respiratory ciliated cells: 82.4" "Cell type enhanced" "Detected in all" "ependymal cell: 87.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039900 Enhanced Approved "Golgi apparatus,Microtubules,Primary cilium transition zone" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" 41 "Golgi apparatus, Microtubules" "Primary cilium transition zone" "HPA039900: " "unprognostic (8.29e-2)" "unprognostic (1.43e-1)" "unprognostic (3.57e-2)" "unprognostic (1.60e-1)" "unprognostic (7.09e-2)" "unprognostic (3.82e-2)" "unprognostic (2.07e-2)" "potential prognostic unfavorable (5.91e-4)" "unprognostic (1.91e-1)" "unprognostic (7.10e-3)" "unprognostic (1.23e-3)" "unprognostic (3.62e-1)" "unprognostic (8.35e-3)" "unprognostic (1.99e-3)" "unprognostic (1.19e-2)" "unprognostic (1.33e-1)" "unprognostic (1.27e-2)" "unprognostic (9.08e-2)" "unprognostic (1.63e-1)" "unprognostic (2.92e-1)" "unprognostic (2.12e-1)" "unprognostic (8.17e-2)" "unprognostic (1.30e-1)" "unprognostic (2.00e-2)" "unprognostic (2.51e-1)" "unprognostic (4.22e-2)" "unprognostic (2.56e-2)" "unprognostic (2.08e-1)" "unprognostic (4.23e-1)" "unprognostic (3.92e-2)" "unprognostic (1.58e-1)" TCTN3 "C10orf61, DKFZP564D116, JBTS18, TECT3" ENSG00000119977 "Tectonic family member 3" Q6NUS6 10 95659823-95694143 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026987 Approved Approved Microtubules "Intracellular and membrane" Other NA NA 200000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 22: Epididymis - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 52: Non-specific - Mitochondria" "Cluster 82: Dendritic cells - Antigen presentation" 11 Microtubules "HPA026987: " "unprognostic (3.88e-2)" "unprognostic (5.77e-2)" "unprognostic (3.51e-1)" "unprognostic (3.73e-3)" "unprognostic (1.35e-1)" "unprognostic (3.74e-2)" "unprognostic (2.36e-1)" "unprognostic (1.87e-1)" "unprognostic (1.44e-2)" "unprognostic (6.58e-2)" "potential prognostic favorable (1.77e-8)" "unprognostic (9.28e-2)" "unprognostic (1.45e-1)" "unprognostic (2.64e-2)" "unprognostic (2.10e-1)" "unprognostic (1.99e-2)" "unprognostic (1.75e-1)" "unprognostic (2.12e-1)" "unprognostic (3.25e-2)" "unprognostic (2.08e-2)" "unprognostic (1.24e-2)" "unprognostic (1.36e-2)" "unprognostic (6.51e-3)" "unprognostic (2.53e-1)" "unprognostic (9.67e-2)" "unprognostic (4.92e-2)" "unprognostic (2.36e-1)" "unprognostic (3.26e-1)" "unprognostic (1.86e-1)" "unprognostic (1.01e-1)" "unprognostic (1.45e-1)" TDG ENSG00000139372 "Thymine DNA glycosylase" Q13569 12 103965822-103988874 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, Chromatin regulator, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052263 Supported Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 53: Neurons - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 31 Nucleoplasm "Plasma membrane" "HPA052263: " "unprognostic (6.50e-2)" "unprognostic (8.22e-2)" "unprognostic (2.81e-1)" "unprognostic (2.99e-1)" "unprognostic (3.19e-2)" "unprognostic (1.83e-2)" "unprognostic (1.43e-1)" "unprognostic (2.20e-1)" "unprognostic (5.89e-2)" "unprognostic (8.81e-3)" "unprognostic (8.47e-2)" "unprognostic (8.31e-2)" "potential prognostic unfavorable (2.49e-4)" "potential prognostic unfavorable (1.60e-4)" "unprognostic (2.35e-3)" "potential prognostic unfavorable (8.13e-4)" "unprognostic (9.85e-3)" "unprognostic (1.05e-1)" "unprognostic (7.19e-3)" "unprognostic (8.64e-2)" "unprognostic (2.52e-3)" "unprognostic (2.01e-1)" "unprognostic (3.98e-3)" "unprognostic (3.07e-2)" "unprognostic (2.52e-1)" "unprognostic (4.01e-2)" "unprognostic (9.44e-2)" "unprognostic (3.64e-1)" "unprognostic (3.64e-1)" "unprognostic (2.54e-2)" "unprognostic (3.07e-1)" TDGF1 "CR, CR-1, CRIPTO, Cripto-1" ENSG00000241186 "Teratocarcinoma-derived growth factor 1" P13385 3 46574534-46582457 "Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 18.8;lymphoid tissue: 19.7;ovary: 9.4" "Cell type enhanced" "Detected in some" "Early spermatids: 5.2;Granulosa cells: 22.7;Loop of henle epithelial cells: 3.5;Medullary thymic epithelial cells: 9.6;Ovarian stromal cells: 5.6;Retinal horizontal cells: 2.0" "Cell type enriched" "Detected in single" 9 "endothelial cell: 5.4" "Group enriched" "Detected in many" 8 "Colon Adenocarcinoma (TCGA): 27.8;Rectum Adenocarcinoma (TCGA): 35.0;Testicular Germ Cell Tumor (TCGA): 107.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "testis cancer: 61.0" "Group enriched" "Detected in many" 5 "cerebellum: 11.2;pons and medulla: 8.7" HPA051928 Approved Vesicles "Secreted in other tissues" "Growth factor" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 72: Kidney - Transmembrane transport" "Cluster 47: Endothelial cells - Vasculature" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 94: Gonadal somatic cells - Mixed function" 24 Vesicles "HPA051928: " "unprognostic (3.08e-1)" "unprognostic (1.52e-1)" "unprognostic (6.08e-2)" "unprognostic (2.65e-2)" "potential prognostic unfavorable (3.77e-4)" "unprognostic (1.49e-1)" "unprognostic (4.41e-2)" "potential prognostic favorable (7.91e-4)" "unprognostic (7.36e-3)" "unprognostic (9.36e-2)" "unprognostic (1.97e-1)" "unprognostic (1.91e-1)" "unprognostic (3.14e-2)" "unprognostic (1.19e-1)" TDGF1P3 "CR-3, CRIPTO-3, CRIPTO3, TDGF2, TDGF3" ENSG00000225366 "Teratocarcinoma-derived growth factor 1 pseudogene 3" P51864 X 110520896-110523021 "Predicted intracellular proteins" "Growth factor" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA051928 Approved Vesicles NA NA "Cluster 10: Cerebellum - Nucleic acid binding" Vesicles "HPA051928: " TDO2 "TDO, TPH2" ENSG00000151790 "Tryptophan 2,3-dioxygenase" P48775 4 155854738-155920406 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Tryptophan catabolism" "Dioxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 47 "liver: 739.5" "Cell type enriched" "Detected in some" 8 "Hepatocytes: 166.6" "Cell type enhanced" "Detected in many" "hippocampal dentate gyrus: 64.3;thalamic excitatory: 63.7" "Cancer enriched" "Detected in many" 15 "Liver Hepatocellular Carcinoma (TCGA): 101.8" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Pituitary gland - Gonadotropes" "Group enriched" "Detected in some" 7 "cerebellum: 6.3;hippocampal formation: 5.3;white matter: 1.9" "Low region specificity" "Detected in all" HPA039611 Uncertain Approved "Plasma membrane,Primary cilium,Basal body,Cytosol" NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 53: Neurons - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 27 "Plasma membrane, Cytosol" "Primary cilium, Basal body" "HPA039611: " "unprognostic (1.69e-2)" "unprognostic (5.86e-2)" "unprognostic (8.75e-2)" "unprognostic (2.70e-2)" "unprognostic (7.83e-2)" "unprognostic (8.73e-2)" "unprognostic (1.70e-3)" "unprognostic (5.02e-2)" "unprognostic (3.61e-1)" "unprognostic (1.17e-1)" "unprognostic (1.38e-3)" "unprognostic (8.11e-3)" "unprognostic (2.21e-1)" "unprognostic (1.89e-3)" "unprognostic (6.76e-2)" "unprognostic (2.10e-3)" "unprognostic (4.66e-2)" "unprognostic (4.13e-1)" "unprognostic (3.67e-2)" "unprognostic (1.46e-2)" "unprognostic (1.50e-1)" "unprognostic (1.06e-2)" "unprognostic (3.92e-1)" "unprognostic (1.34e-1)" "unprognostic (1.08e-2)" "unprognostic (1.40e-1)" "unprognostic (4.90e-2)" "unprognostic (3.40e-2)" TDP1 "FLJ11090, SCAN1" ENSG00000042088 "Tyrosyl-DNA phosphodiesterase 1" Q9NUW8 14 89954939-90044764 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "Exonuclease, Hydrolase, Nuclease" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 165.8;Late primary spermatocytes: 100.2;Oocytes: 78.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin), Spleen - B-cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071317 Approved Supported "Nucleoplasm,Plasma membrane" No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 31: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 27 Nucleoplasm "Plasma membrane" "HPA071317: " "unprognostic (3.20e-2)" "unprognostic (2.92e-1)" "unprognostic (3.48e-1)" "unprognostic (1.83e-3)" "unprognostic (5.21e-3)" "unprognostic (3.27e-2)" "unprognostic (7.24e-2)" "unprognostic (3.78e-3)" "unprognostic (7.09e-2)" "unprognostic (4.80e-3)" "potential prognostic favorable (8.10e-5)" "unprognostic (2.60e-1)" "unprognostic (1.94e-1)" "potential prognostic unfavorable (2.45e-5)" "unprognostic (2.28e-2)" "potential prognostic unfavorable (1.87e-4)" "unprognostic (4.07e-2)" "unprognostic (1.76e-2)" "unprognostic (3.28e-1)" "unprognostic (4.31e-2)" "unprognostic (2.80e-2)" "unprognostic (2.71e-2)" "unprognostic (1.42e-1)" "unprognostic (6.47e-2)" "potential prognostic favorable (3.43e-4)" "unprognostic (8.47e-2)" "unprognostic (3.33e-2)" "unprognostic (2.19e-1)" "unprognostic (1.47e-1)" "unprognostic (2.28e-3)" "unprognostic (1.32e-1)" TDP2 TTRAP ENSG00000111802 "Tyrosyl-DNA phosphodiesterase 2" O95551 6 24649979-24666930 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction" "Hydrolase, Nuclease" "Intellectual disability, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 172.6" "Cell type enhanced" "Detected in many" "Colonocytes: 526.7;Early spermatids: 197.3;Enterocytes: 656.8;Goblet cells: 222.1;Neutrophils: 336.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 75.8;neutrophil: 229.6" "Lineage enriched" "Detected in all" 7 "granulocytes: 229.6" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Prostate - Prostate glandular cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB073398, HPA074011" Enhanced Supported "Nucleoplasm,Nuclear bodies" "Intracellular and membrane" Enzyme No No "Cluster 35: Neutrophils - Protein binding" "Cluster 77: Intestine - Digestion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 13 "Nucleoplasm, Nuclear bodies" "CAB073398: , HPA074011: " "unprognostic (6.71e-2)" "unprognostic (1.59e-2)" "unprognostic (8.05e-2)" "unprognostic (2.89e-2)" "unprognostic (1.88e-1)" "potential prognostic favorable (5.31e-5)" "unprognostic (9.58e-2)" "unprognostic (1.19e-1)" "unprognostic (4.53e-2)" "unprognostic (7.37e-3)" "potential prognostic favorable (6.13e-8)" "unprognostic (1.01e-3)" "unprognostic (3.26e-2)" "unprognostic (2.12e-3)" "unprognostic (1.04e-1)" "unprognostic (7.72e-2)" "unprognostic (1.59e-1)" "unprognostic (1.45e-1)" "unprognostic (1.16e-1)" "potential prognostic favorable (3.00e-4)" "unprognostic (8.30e-3)" "unprognostic (7.87e-2)" "unprognostic (2.99e-2)" "potential prognostic unfavorable (5.04e-4)" "unprognostic (8.56e-2)" "potential prognostic unfavorable (7.97e-5)" "potential prognostic unfavorable (3.28e-4)" "unprognostic (1.21e-1)" "unprognostic (1.09e-1)" "unprognostic (1.97e-1)" "unprognostic (1.21e-1)" TDRD1 CT41.1 ENSG00000095627 "Tudor domain containing 1" Q9BXT4 10 114179270-114232666 "Plasma proteins, Predicted intracellular proteins" "Differentiation, Meiosis, RNA-mediated gene silencing, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "testis: 14.7" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 37.5;Early primary spermatocytes: 28.9;Early spermatids: 12.4;Late primary spermatocytes: 29.5;Oocytes: 96.7;Undifferentiated spermatogonia: 53.7" "Cell type enhanced" "Detected in some" "fibroblast: 8.1;pericyte: 17.2;vascular associated smooth muscle cell: 7.1" "Cancer enriched" "Detected in some" 5 "Prostate Adenocarcinoma (TCGA): 6.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.6" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in some" "cervical cancer: 7.5;prostate cancer: 5.8" "Heart muscle - Cardiomyocytes, Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA037729 Enhanced NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 57: Testis - Spermatogenesis" "Cluster 48: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" "HPA037729: " "unprognostic (5.32e-3)" "unprognostic (1.81e-1)" "unprognostic (8.46e-3)" "unprognostic (1.43e-1)" "unprognostic (2.42e-1)" "unprognostic (2.06e-1)" "unprognostic (2.72e-1)" "unprognostic (1.09e-1)" TDRD10 DKFZp434M202 ENSG00000163239 "Tudor domain containing 10" Q5VZ19 1 154502219-154548147 "Cancer-related genes, Predicted intracellular proteins" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 52.5" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 84.4;Early spermatids: 173.4;Kupffer cells: 41.0;Late primary spermatocytes: 139.6;Late spermatids: 331.7;Mesothelial cells: 38.2;Undifferentiated spermatogonia: 47.5;Vascular endothelial cells: 43.6" "Cell type enriched" "Detected in some" 4 "endothelial cell: 51.7" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 7.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "thyroid cancer: 2.2" "Breast - Endothelial cells, Colon - Endothelial cells, Minor Salivary Gland - Endothelial cells, Skin - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in some" HPA054327 Approved Vesicles NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 4: Non-specific - Transcription" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" Vesicles "HPA054327: " "unprognostic (1.57e-2)" "unprognostic (8.03e-2)" "unprognostic (1.22e-1)" "unprognostic (5.62e-2)" "unprognostic (2.27e-1)" "unprognostic (5.25e-3)" "potential prognostic favorable (2.26e-4)" "unprognostic (2.23e-1)" "unprognostic (3.74e-1)" "unprognostic (5.39e-3)" TDRD12 "ECAT8, FLJ13072" ENSG00000173809 "Tudor domain containing 12" Q587J7 19 32719753-32829580 "Enzymes, Predicted intracellular proteins" "Differentiation, Meiosis, RNA-mediated gene silencing, Spermatogenesis" "Developmental protein, Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "testis: 13.4" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 86.5;Early primary spermatocytes: 107.1;Early spermatids: 22.5;Epididymal principal cells: 26.5;Late primary spermatocytes: 46.8;Late spermatids: 15.7;Oocytes: 46.1;Undifferentiated spermatogonia: 65.5" "Cell type enhanced" "Detected in many" "medium spiny neuron: 11.8" "Cancer enriched" "Detected in some" 6 "Testicular Germ Cell Tumor (TCGA): 20.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 4.5;Myeloma: 2.3" "Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 1: Neurons - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" "unprognostic (1.20e-1)" "unprognostic (7.07e-2)" "unprognostic (1.64e-1)" "unprognostic (3.21e-1)" "unprognostic (7.97e-3)" "unprognostic (3.56e-1)" "unprognostic (6.09e-3)" "unprognostic (3.78e-2)" "unprognostic (2.92e-2)" "unprognostic (9.17e-3)" TDRD15 ENSG00000218819 "Tudor domain containing 15" B5MCY1 2 21123968-21144368 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 5 "testis: 5.1" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 7.6;Early primary spermatocytes: 39.9;Early spermatids: 6.4;Gonadotrophs: 10.8;Late primary spermatocytes: 37.8;Late spermatids: 22.7;Undifferentiated spermatogonia: 5.3" "Cell type enhanced" "Detected in some" "fibroblast: 8.2;leukocyte: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "Myeloma: 1.0" "Testis - Spermatocytes" "HPA051770, HPA054675" Uncertain NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 20: Myeloma - Immune response" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" "HPA051770: , HPA054675: " TDRD3 FLJ21007 ENSG00000083544 "Tudor domain containing 3" Q9H7E2 13 60396457-60573878 "Predicted intracellular proteins" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 475.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034925, HPA067153" Approved Enhanced "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 58: Mast cells - Allergic inflammatory responses" 28 Nucleoplasm "Golgi apparatus, Cytosol" "CAB034925: , HPA067153: " "unprognostic (4.86e-2)" "unprognostic (1.97e-1)" "unprognostic (2.71e-2)" "unprognostic (1.55e-2)" "unprognostic (4.08e-1)" "unprognostic (8.32e-3)" "unprognostic (5.33e-2)" "unprognostic (3.16e-1)" "unprognostic (1.07e-1)" "unprognostic (1.21e-3)" "validated prognostic favorable (2.92e-5)" "validated prognostic favorable (4.95e-5)" "potential prognostic favorable (1.24e-5)" "unprognostic (2.85e-1)" "unprognostic (5.37e-2)" "unprognostic (1.06e-1)" "unprognostic (2.42e-2)" "unprognostic (3.92e-2)" "unprognostic (1.87e-1)" "unprognostic (3.67e-1)" "unprognostic (3.64e-2)" "unprognostic (1.25e-1)" "unprognostic (1.03e-1)" "unprognostic (1.75e-2)" "unprognostic (1.30e-2)" "unprognostic (1.47e-1)" "unprognostic (1.32e-1)" "unprognostic (8.16e-2)" "unprognostic (2.89e-1)" "unprognostic (3.49e-2)" "unprognostic (2.35e-2)" TDRD5 "FLJ34823, TUDOR3" ENSG00000162782 "Tudor domain containing 5" Q8NAT2 1 179591613-179691272 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 6.2;testis: 20.4" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 21.3;Brain inhibitory neurons: 24.1;Early primary spermatocytes: 44.8;Early spermatids: 72.0;Epididymal principal cells: 22.3;Lacrimal acinar cells: 23.6;Late primary spermatocytes: 42.1;Podocytes: 69.7;Retinal pigment epithelial cells: 29.8;Undifferentiated spermatogonia: 26.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Esophageal cancer: 2.5" "Breast - Breast glandular cells, Breast - Breast glandular cells, Prostate - Prostate glandular cells, Testis - Spermatocytes" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA029418 Enhanced NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 24: Neurons - Mixed function" "Cluster 20: Myeloma - Immune response" "Cluster 35: Neurons - Synaptic function & neurogenesis" "HPA029418: " "unprognostic (1.31e-1)" "unprognostic (1.68e-1)" "unprognostic (3.37e-1)" "unprognostic (8.90e-2)" "unprognostic (2.94e-1)" "unprognostic (2.49e-1)" "unprognostic (2.13e-3)" "unprognostic (1.18e-1)" "unprognostic (1.60e-1)" "unprognostic (2.42e-1)" "unprognostic (1.76e-2)" "unprognostic (6.51e-2)" "unprognostic (2.11e-2)" "unprognostic (5.19e-2)" "unprognostic (8.05e-2)" "unprognostic (1.58e-1)" "unprognostic (9.05e-2)" "unprognostic (1.01e-2)" "unprognostic (9.20e-2)" TDRD6 "bA446F17.4, CT41.2, NY-CO-45, SPATA36" ENSG00000180113 "Tudor domain containing 6" O60522 6 46687875-46704319 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 25.9" "Group enriched" "Detected in many" 5 "Early primary spermatocytes: 67.0;Early spermatids: 248.4;Late primary spermatocytes: 206.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 8.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "prostate cancer: 2.9" "Testis - Spermatocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA075923 Enhanced Approved "Endoplasmic reticulum,Vesicles,Cytosol" NA NA "Cluster 67: Testis - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 11: Neuronal - Sensory perception" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" "Endoplasmic reticulum, Vesicles, Cytosol" "HPA075923: " "unprognostic (2.62e-2)" "unprognostic (5.86e-2)" "unprognostic (4.37e-2)" "unprognostic (2.61e-1)" "unprognostic (2.66e-2)" "unprognostic (5.88e-2)" "potential prognostic favorable (8.61e-5)" "unprognostic (4.54e-2)" "unprognostic (1.96e-1)" "unprognostic (3.00e-1)" "potential prognostic favorable (2.05e-6)" "unprognostic (2.21e-1)" "unprognostic (5.43e-2)" "unprognostic (1.54e-1)" "unprognostic (2.91e-3)" TDRD7 PCTAIRE2BP ENSG00000196116 "Tudor domain containing 7" Q8NHU6 9 97412096-97496125 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" RNA-binding "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 58.4" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 214.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020800, HPA022250, HPA024529" Enhanced Supported "Nucleoplasm,Cytoplasmic bodies" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 42: Retina - Visual perception" "Cluster 27: Non-specific - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 79: Photoreceptor cells - Phototransduction" 9 "Cytoplasmic bodies" Nucleoplasm "CAB020800: , HPA022250: , HPA024529: " "unprognostic (9.68e-2)" "unprognostic (2.40e-2)" "unprognostic (9.00e-2)" "unprognostic (2.60e-2)" "unprognostic (4.54e-3)" "unprognostic (1.65e-3)" "unprognostic (2.24e-1)" "unprognostic (7.82e-3)" "unprognostic (2.78e-1)" "unprognostic (2.05e-2)" "potential prognostic favorable (1.18e-9)" "unprognostic (1.81e-3)" "unprognostic (1.82e-1)" "unprognostic (7.43e-3)" "unprognostic (2.78e-1)" "unprognostic (2.97e-2)" "unprognostic (1.01e-1)" "unprognostic (2.85e-2)" "unprognostic (2.64e-1)" "unprognostic (6.47e-2)" "unprognostic (2.09e-2)" "unprognostic (1.62e-1)" "unprognostic (1.56e-1)" "unprognostic (4.79e-2)" "unprognostic (5.88e-3)" "unprognostic (1.21e-1)" "unprognostic (1.93e-1)" "unprognostic (5.28e-2)" "unprognostic (1.31e-1)" "unprognostic (7.97e-2)" "unprognostic (2.37e-1)" TDRD9 "C14orf75, DKFZp434N0820, FLJ36164, NET54" ENSG00000156414 "Tudor domain containing 9" Q8NDG6 14 103928456-104052667 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Differentiation, Meiosis, RNA-mediated gene silencing, Spermatogenesis" "Developmental protein, Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "parathyroid gland: 26.2;testis: 35.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 218.4;Differentiating spermatogonia: 107.9;Early primary spermatocytes: 131.1;Epididymal efferent duct ciliated cells: 97.4;Fallopian tube ciliated cells: 91.4;Neutrophil progenitors: 84.5;Neutrophils: 412.6;Retinal pigment epithelial cells: 157.7;Undifferentiated spermatogonia: 70.3" "Cell type enhanced" "Detected in all" "hippocampal dentate gyrus: 47.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "classical monocyte: 1.5" "Lineage enriched" "Detected in single" 6 "monocytes: 1.5" "Cancer enhanced" "Detected in many" "cervical cancer: 16.9;thyroid cancer: 7.7" "Adipose visceral - Neutrophils, Lung - Neutrophils_2, Pituitary gland - Somatotropes, Spleen - Neutrophils_2, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" "unprognostic (4.60e-1)" "unprognostic (9.39e-2)" "unprognostic (5.65e-2)" "unprognostic (4.65e-2)" "unprognostic (1.41e-2)" "unprognostic (4.56e-1)" "unprognostic (4.23e-3)" "unprognostic (6.10e-2)" "unprognostic (1.72e-3)" "unprognostic (1.26e-1)" "unprognostic (2.40e-1)" "unprognostic (1.52e-1)" "unprognostic (5.98e-2)" "unprognostic (1.16e-1)" "unprognostic (4.70e-3)" TDRKH TDRD2 ENSG00000182134 "Tudor and KH domain containing" Q9Y2W6 1 151770107-151791416 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, RNA-mediated gene silencing, Spermatogenesis" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 28.3;testis: 20.7" "Cell type enhanced" "Detected in many" "Breast lactating cells: 46.9;Early primary spermatocytes: 61.2;Early spermatids: 38.9;Late primary spermatocytes: 46.6;Late spermatids: 112.3;Oocytes: 82.9;Platelets: 46.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016419, HPA019625" Approved Approved Centrosome,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 12 Cytosol Centrosome "HPA016419: , HPA019625: " "unprognostic (1.60e-1)" "potential prognostic unfavorable (9.18e-4)" "unprognostic (6.73e-2)" "unprognostic (1.92e-1)" "unprognostic (2.25e-2)" "unprognostic (2.01e-1)" "unprognostic (1.52e-1)" "potential prognostic favorable (1.73e-4)" "unprognostic (8.86e-2)" "unprognostic (8.37e-2)" "unprognostic (3.19e-3)" "unprognostic (6.58e-2)" "unprognostic (1.11e-2)" "unprognostic (2.28e-2)" "unprognostic (5.75e-3)" "unprognostic (7.45e-3)" "unprognostic (3.76e-1)" "unprognostic (2.51e-2)" "unprognostic (1.52e-1)" "unprognostic (3.06e-1)" "unprognostic (4.66e-3)" "unprognostic (1.34e-1)" "unprognostic (3.59e-1)" "unprognostic (2.38e-1)" "unprognostic (1.84e-1)" "unprognostic (1.42e-1)" "unprognostic (4.44e-1)" "unprognostic (1.51e-1)" "unprognostic (5.03e-2)" "unprognostic (8.75e-3)" "unprognostic (1.08e-1)" TDRP "C8orf42, INM01, TDRP1, TDRP2" ENSG00000180190 "Testis development related protein" Q86YL5 8 489803-545781 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 260.9;Migrating cytotrophoblasts: 229.7;Syncytiotrophoblasts: 506.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 25.2" "Lung - Respiratory ciliated cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008462 Approved Supported Vesicles,Cytosol NA NA 35000 "Cluster 65: Brain - Transcription" "Cluster 23: Choroid plexus - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" "Vesicles, Cytosol" "HPA008462: " "unprognostic (2.67e-2)" "unprognostic (2.60e-1)" "unprognostic (4.96e-2)" "unprognostic (9.57e-2)" "unprognostic (1.10e-1)" "unprognostic (1.12e-2)" "unprognostic (9.94e-2)" "unprognostic (2.61e-2)" "unprognostic (6.70e-2)" "unprognostic (1.95e-3)" "unprognostic (2.35e-1)" "unprognostic (5.71e-2)" "unprognostic (2.45e-2)" "unprognostic (2.51e-1)" "unprognostic (1.80e-1)" "unprognostic (2.76e-1)" "unprognostic (1.30e-1)" "unprognostic (3.32e-1)" "unprognostic (1.48e-3)" "unprognostic (1.08e-2)" "unprognostic (1.58e-1)" "unprognostic (5.67e-3)" "unprognostic (8.82e-2)" "unprognostic (2.58e-3)" "potential prognostic unfavorable (5.73e-4)" "unprognostic (3.57e-2)" "unprognostic (1.42e-1)" "unprognostic (3.80e-2)" TEAD1 "AA, TCF13, TEF-1" ENSG00000187079 "TEA domain transcription factor 1" P28347 11 12674421-12944737 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 1776.2;Endometrial luminal cells: 1037.1;Myonuclei: 1112.5;Podocytes: 959.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Minor Salivary Gland - Endothelial cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057339, HPA062471" Enhanced Nucleoplasm NA NA "Cluster 63: Non-specific - Basic cellular processes" "Cluster 46: Brainstem - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 51: Secretory epithelial cells - Mixed function" 23 Nucleoplasm "HPA057339: , HPA062471: " "unprognostic (4.02e-2)" "unprognostic (7.36e-2)" "unprognostic (2.60e-1)" "unprognostic (3.11e-2)" "unprognostic (3.21e-1)" "unprognostic (1.15e-1)" "unprognostic (2.83e-1)" "unprognostic (1.02e-1)" "unprognostic (2.14e-1)" "unprognostic (5.16e-3)" "potential prognostic favorable (1.03e-5)" "unprognostic (2.58e-2)" "unprognostic (4.63e-1)" "unprognostic (1.56e-1)" "unprognostic (3.10e-1)" "unprognostic (1.81e-1)" "potential prognostic unfavorable (9.20e-5)" "unprognostic (8.50e-2)" "unprognostic (7.27e-2)" "unprognostic (7.42e-3)" "unprognostic (3.69e-2)" "unprognostic (1.26e-1)" "unprognostic (2.72e-2)" "unprognostic (8.03e-2)" "unprognostic (1.35e-2)" "unprognostic (1.04e-2)" "unprognostic (8.84e-2)" "unprognostic (3.44e-2)" "unprognostic (3.57e-1)" "unprognostic (1.30e-1)" "unprognostic (4.65e-1)" TEAD2 "ETF, TEF-4, TEF4" ENSG00000074219 "TEA domain transcription factor 2" Q15562 19 49340595-49362457 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast lactating cells: 42.0;Decidual stromal cells: 40.5;Early spermatids: 85.0;Extravillous trophoblasts: 34.6;Late primary spermatocytes: 35.8;Late spermatids: 38.2;Lymphatic endothelial cells: 48.4;Pericytes: 35.2;Vascular endothelial cells: 44.9" "Cell type enhanced" "Detected in some" "endothelial cell: 19.4;pericyte: 30.2;vascular associated smooth muscle cell: 19.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 22 "memory B-cell: 1.7;naive B-cell: 2.7" "Lineage enriched" "Detected in single" 27 "B-cells: 2.7" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066292, HPA069963" Supported Nucleoplasm NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 35: Non-specific - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 5: Rhabdoid - Unknown function" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 12 Nucleoplasm "HPA066292: , HPA069963: " "unprognostic (1.79e-1)" "unprognostic (2.11e-1)" "unprognostic (7.74e-2)" "unprognostic (2.38e-2)" "unprognostic (1.99e-1)" "unprognostic (1.40e-1)" "unprognostic (2.41e-2)" "unprognostic (2.73e-2)" "unprognostic (3.66e-1)" "unprognostic (1.27e-2)" "unprognostic (3.16e-2)" "unprognostic (4.39e-2)" "unprognostic (2.66e-2)" "potential prognostic unfavorable (2.41e-4)" "unprognostic (2.91e-2)" "unprognostic (1.64e-1)" "unprognostic (2.07e-1)" "unprognostic (1.96e-1)" "unprognostic (1.85e-1)" "unprognostic (3.08e-1)" "unprognostic (3.38e-1)" "unprognostic (4.41e-3)" "unprognostic (5.42e-2)" "unprognostic (1.36e-1)" "unprognostic (4.41e-1)" "unprognostic (2.56e-1)" "unprognostic (1.40e-2)" "unprognostic (2.19e-2)" "unprognostic (7.16e-2)" "unprognostic (1.71e-1)" "unprognostic (1.86e-1)" TEAD3 "ETFR-1, TEAD5, TEF-5" ENSG00000007866 "TEA domain transcription factor 3" Q99594 6 35473597-35497079 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 126.3;Esophageal apical cells: 131.6;Extravillous trophoblasts: 126.9;Smooth muscle cells: 105.1;Syncytiotrophoblasts: 268.4" "Cell type enhanced" "Detected in some" "pericyte: 28.2;vascular associated smooth muscle cell: 58.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Lung - Smooth muscle cells, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Endothelial cells, Prostate - Smooth muscle cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA028906 Uncertain NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 13 "HPA028906: " "unprognostic (3.01e-1)" "unprognostic (6.08e-2)" "unprognostic (7.87e-2)" "unprognostic (2.51e-1)" "unprognostic (1.69e-1)" "unprognostic (2.02e-2)" "unprognostic (1.68e-1)" "potential prognostic unfavorable (3.74e-5)" "unprognostic (1.81e-1)" "unprognostic (1.10e-1)" "unprognostic (8.88e-2)" "unprognostic (1.75e-3)" "unprognostic (1.43e-2)" "unprognostic (3.38e-2)" "unprognostic (2.37e-2)" "unprognostic (4.94e-3)" "unprognostic (1.03e-1)" "unprognostic (1.39e-1)" "unprognostic (1.76e-1)" "unprognostic (2.64e-1)" "unprognostic (1.12e-1)" "unprognostic (1.45e-2)" "unprognostic (1.43e-1)" "unprognostic (2.62e-1)" "unprognostic (1.86e-1)" "unprognostic (1.14e-1)" "unprognostic (7.77e-3)" "unprognostic (1.79e-1)" "unprognostic (1.85e-1)" "unprognostic (1.62e-1)" "unprognostic (1.41e-1)" TEAD4 "EFTR-2, RTEF-1, TCF13L1, TEF-3, TEFR-1" ENSG00000197905 "TEA domain transcription factor 4" Q15561 12 2959330-3040676 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 122.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 63.1;Cytotrophoblasts: 85.0;Migrating cytotrophoblasts: 81.2;Myonuclei: 139.1;Pancreatic acinar cells: 81.9;Salivary myoepithelial cells: 63.6;Thymic myoid cells: 61.2;Vascular endothelial cells: 76.0" "Group enriched" "Detected in some" 4 "endothelial cell: 46.5;vascular associated smooth muscle cell: 15.7" "Cancer enriched" "Detected in all" 5 "Testicular Germ Cell Tumor (TCGA): 179.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Endothelial cells, Pituitary gland - Endothelial cells, Skin - Keratinocyte (granular), Testis - Spermatogonia" "Region enriched" "Detected in single" 5 "cerebellum: 3.1" "Low region specificity" "Detected in all" HPA056896 Uncertain Supported Nucleoplasm NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 12: Non-specific - Vasculature" "Cluster 38: Non-specific - Transcription" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 50 Nucleoplasm "HPA056896: " "unprognostic (2.74e-1)" "unprognostic (2.01e-1)" "unprognostic (4.07e-1)" "unprognostic (2.40e-1)" "unprognostic (3.29e-1)" "unprognostic (3.64e-2)" "unprognostic (9.75e-2)" "unprognostic (2.55e-2)" "unprognostic (1.98e-1)" "unprognostic (7.12e-2)" "unprognostic (5.05e-3)" "unprognostic (3.34e-2)" "unprognostic (1.78e-1)" "unprognostic (5.94e-3)" "unprognostic (1.58e-1)" "unprognostic (1.64e-3)" "potential prognostic unfavorable (1.36e-4)" "unprognostic (3.42e-1)" "unprognostic (2.17e-2)" "unprognostic (9.98e-2)" "unprognostic (1.13e-1)" "unprognostic (3.64e-3)" "unprognostic (2.18e-2)" "unprognostic (4.78e-2)" "unprognostic (1.74e-1)" "unprognostic (1.46e-2)" "unprognostic (4.22e-2)" "unprognostic (1.50e-2)" "unprognostic (2.32e-1)" "unprognostic (9.87e-3)" "unprognostic (7.04e-2)" TEC PSCTK4 ENSG00000135605 "Tec protein tyrosine kinase" P42680 4 48135783-48269838 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 157.2;Esophageal apical cells: 172.5;Hematopoietic stem cells: 248.4;Innate lymphoid cells: 154.8;Mast cells: 164.4;Megakaryocyte progenitors: 353.8;Megakaryocyte-Erythroid progenitors: 163.5;Neutrophil progenitors: 153.3;Thymocytes: 160.1" "Cell type enhanced" "Detected in many" "endothelial cell: 50.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "basophil: 20.8;eosinophil: 13.4" "Lineage enriched" "Detected in many" 6 "granulocytes: 20.8" "Cancer enhanced" "Detected in many" "Myeloma: 12.4" "Adipose subcutaneous - Macrophages, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA005733, HPA024657" Approved Supported "Plasma membrane" NA NA "Cluster 32: Basophils - Transcription" "Cluster 58: Skin - Keratinization" "Cluster 49: Hindbrain - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 7 "Plasma membrane" "HPA005733: , HPA024657: " "unprognostic (2.81e-2)" "unprognostic (6.87e-2)" "unprognostic (1.06e-1)" "unprognostic (7.79e-2)" "unprognostic (9.69e-3)" "potential prognostic favorable (6.15e-5)" "unprognostic (1.88e-1)" "unprognostic (8.38e-2)" "unprognostic (1.06e-1)" "unprognostic (8.04e-2)" "unprognostic (3.29e-1)" "unprognostic (2.54e-3)" "unprognostic (7.59e-3)" "unprognostic (4.69e-2)" "unprognostic (1.15e-3)" "unprognostic (7.22e-3)" "unprognostic (5.01e-2)" "unprognostic (1.40e-1)" "unprognostic (2.33e-1)" "unprognostic (1.40e-1)" "unprognostic (1.61e-1)" TECPR1 "DKFZP434B0335, FLJ23419, FLJ90593, KIAA1358" ENSG00000205356 "Tectonin beta-propeller repeat containing 1" Q7Z6L1 7 98214624-98252232 "Predicted intracellular proteins" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 82.8;Salivary acinar cells: 70.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021061 Approved Supported Vesicles NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 64: Non-specific - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 7 Vesicles "HPA021061: " "unprognostic (1.04e-1)" "unprognostic (1.56e-1)" "unprognostic (5.86e-2)" "unprognostic (4.21e-2)" "unprognostic (1.05e-1)" "unprognostic (7.27e-2)" "unprognostic (3.29e-1)" "unprognostic (3.02e-1)" "unprognostic (5.40e-2)" "potential prognostic unfavorable (1.92e-4)" "unprognostic (4.42e-3)" "unprognostic (2.27e-1)" "unprognostic (1.18e-3)" "unprognostic (1.91e-3)" "unprognostic (2.29e-3)" "unprognostic (1.22e-3)" "unprognostic (2.76e-1)" "unprognostic (2.33e-1)" "unprognostic (1.33e-1)" "unprognostic (1.07e-1)" "unprognostic (1.51e-1)" "potential prognostic favorable (1.97e-4)" "unprognostic (3.02e-1)" "unprognostic (1.70e-2)" "unprognostic (1.92e-1)" "unprognostic (4.55e-2)" "unprognostic (7.62e-2)" "unprognostic (3.35e-1)" "unprognostic (9.79e-2)" "unprognostic (1.77e-1)" "unprognostic (6.98e-2)" TECPR2 KIAA0329 ENSG00000196663 "Tectonin beta-propeller repeat containing 2" O15040 14 102362941-102502477 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Autophagy "Hereditary spastic paraplegia, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Neutrophils: 1480.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "neutrophil: 7.3" "Lineage enriched" "Detected in single" 14 "granulocytes: 7.3" "Low cancer specificity" "Detected in all" "Spleen - Neutrophils_2, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000658 Enhanced Approved Nucleoplasm,Nucleoli,Centrosome NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 24: Neutrophils - Innate immunity signal integration" 5 Nucleoplasm "Nucleoli, Centrosome" "HPA000658: " "unprognostic (4.15e-1)" "unprognostic (1.17e-1)" "unprognostic (1.90e-1)" "unprognostic (2.37e-2)" "unprognostic (7.73e-2)" "unprognostic (1.20e-1)" "unprognostic (1.13e-1)" "unprognostic (1.43e-1)" "unprognostic (9.89e-3)" "unprognostic (3.67e-3)" "potential prognostic favorable (1.35e-6)" "unprognostic (1.32e-3)" "potential prognostic favorable (7.49e-4)" "potential prognostic unfavorable (3.00e-4)" "unprognostic (1.26e-2)" "unprognostic (1.08e-1)" "unprognostic (3.18e-2)" "unprognostic (3.37e-1)" "unprognostic (1.97e-1)" "unprognostic (2.45e-1)" "unprognostic (6.41e-2)" "unprognostic (3.09e-2)" "unprognostic (7.92e-2)" "unprognostic (3.19e-1)" "unprognostic (2.35e-1)" "unprognostic (1.08e-1)" "unprognostic (6.07e-2)" "unprognostic (3.61e-2)" "unprognostic (1.78e-1)" "unprognostic (3.93e-1)" "unprognostic (1.57e-1)" TECR "GPSN2, MRT14, SC2, TER" ENSG00000099797 "Trans-2,3-enoyl-CoA reductase" Q9NZ01 19 14517085-14565980 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Sphingolipid metabolism" Oxidoreductase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 1246.2;Esophageal suprabasal cells: 624.3;Extravillous trophoblasts: 499.1;Late spermatids: 1461.5" "Cell type enhanced" "Detected in all" "pericyte: 182.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029780, HPA056488" Supported Supported "Endoplasmic reticulum" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 52 "Endoplasmic reticulum" "HPA029780: , HPA056488: " "unprognostic (2.60e-2)" "unprognostic (4.69e-1)" "unprognostic (1.97e-1)" "potential prognostic favorable (5.58e-4)" "unprognostic (1.92e-1)" "unprognostic (1.65e-1)" "unprognostic (1.06e-1)" "unprognostic (1.51e-1)" "unprognostic (2.15e-1)" "unprognostic (1.26e-1)" "unprognostic (4.25e-3)" "unprognostic (1.72e-1)" "unprognostic (1.05e-1)" "unprognostic (1.67e-2)" "unprognostic (6.06e-3)" "unprognostic (1.19e-1)" "unprognostic (3.06e-1)" "unprognostic (1.14e-1)" "unprognostic (7.81e-2)" "unprognostic (6.36e-3)" "unprognostic (7.23e-2)" "unprognostic (1.93e-1)" "unprognostic (1.75e-1)" "unprognostic (2.30e-2)" "unprognostic (4.04e-1)" "unprognostic (7.49e-2)" "unprognostic (3.29e-2)" "unprognostic (3.48e-2)" "unprognostic (1.96e-1)" "unprognostic (3.05e-2)" "unprognostic (5.28e-1)" TECRL "DKFZp313B2333, DKFZp313D0829, GPSN2L, SRD5A2L2, TERL" ENSG00000205678 "Trans-2,3-enoyl-CoA reductase like" Q5HYJ1 4 64275257-64409468 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "heart muscle: 517.7" "Group enriched" "Detected in some" 26 "Cardiomyocytes: 1358.6;Myonuclei: 454.3" "Cell type enhanced" "Detected in some" "committed oligodendrocyte precursor: 1.1;hippocampal CA1-3: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 118 "Rhabdoid: 52.0" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" "Low region specificity" "Detected in single" NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 55: Myocytes - Oxidative muscle function" "unprognostic (2.93e-1)" "unprognostic (7.31e-2)" TECTA "DFNA12, DFNA8, DFNB21" ENSG00000109927 "Tectorin alpha" O75443 11 121101243-121191490 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters" Hearing "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 12.8;Brain inhibitory neurons: 15.8;Choroid plexus epithelial cells: 13.3;Other brain neurons: 16.3;Retinal ganglion cells: 11.6;Thymic myoid cells: 25.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in single" "Glioblastoma Multiforme (TCGA): 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "Sarcoma: 3.3" "Heart muscle - Cardiomyocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA018870 Approved "Secreted in other tissues" Other NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 1: Neurons - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "HPA018870: " "unprognostic (7.67e-2)" "unprognostic (1.40e-1)" "unprognostic (1.38e-2)" TECTB ENSG00000119913 "Tectorin beta" Q96PL2 10 112283400-112305038 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 4 "Retinal pigment epithelial cells: 17.1" "Cell type enhanced" "Detected in single" "hippocampal dentate gyrus: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Secreted in other tissues" "No annotated function" NA NA "Cluster 56: Non-specific - Sensory perception" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" 35 "unprognostic (1.25e-1)" TEDC1 C14orf80 ENSG00000185347 "Tubulin epsilon and delta complex 1" Q86SX3 14 105489855-105499575 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Colonocytes: 26.5;Enteric transient amplifying cells: 29.2;Esophageal basal cells: 22.6;Extravillous trophoblasts: 32.4;Monocyte progenitors: 22.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA039049, HPA039050" Uncertain Uncertain "Nucleoplasm,Golgi apparatus,Cytosol" No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 65: Non-specific - Cell growth & division" 8 "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA039049: , HPA039050: " "unprognostic (4.02e-2)" "unprognostic (1.57e-1)" "unprognostic (6.46e-2)" "unprognostic (2.61e-1)" "unprognostic (1.99e-1)" "unprognostic (5.68e-2)" "unprognostic (1.11e-2)" "unprognostic (9.90e-2)" "unprognostic (2.01e-2)" "unprognostic (1.23e-1)" "unprognostic (1.12e-1)" "unprognostic (1.17e-1)" "potential prognostic unfavorable (5.23e-4)" "unprognostic (7.22e-3)" "unprognostic (2.40e-1)" "unprognostic (8.27e-2)" "unprognostic (5.55e-2)" "unprognostic (2.02e-1)" "unprognostic (4.20e-2)" "unprognostic (8.65e-2)" "unprognostic (1.65e-1)" "unprognostic (3.42e-1)" "unprognostic (7.35e-2)" "unprognostic (2.75e-1)" "unprognostic (4.89e-2)" "unprognostic (1.19e-1)" "unprognostic (1.20e-2)" "unprognostic (1.78e-2)" "unprognostic (2.06e-1)" TEDC2 "C16orf59, FLJ13909" ENSG00000162062 "Tubulin epsilon and delta complex 2" Q7L2K0 16 2460086-2464963 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 3.8;testis: 4.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 15.0;Differentiating spermatogonia: 49.5;Early primary spermatocytes: 13.1;Erythrocyte progenitors: 13.3;Esophageal basal cells: 11.4;Extravillous trophoblasts: 15.3;Megakaryocyte progenitors: 10.4;Migrating cytotrophoblasts: 14.2;Oocytes: 32.2;Undifferentiated spermatogonia: 21.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Lung - Mitotic cells (Lung), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051394, HPA055389" Approved Approved "Nucleoplasm,Cell Junctions" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 35: RS4;11 - Unknown function" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 7 "Nucleoplasm, Cell Junctions" "HPA051394: , HPA055389: " "unprognostic (6.15e-2)" "unprognostic (1.36e-1)" "unprognostic (1.78e-2)" "unprognostic (2.82e-1)" "unprognostic (1.83e-1)" "unprognostic (1.03e-1)" "unprognostic (8.70e-3)" "unprognostic (6.72e-2)" "potential prognostic unfavorable (1.90e-5)" "potential prognostic unfavorable (1.45e-5)" "unprognostic (6.57e-2)" "potential prognostic unfavorable (1.06e-5)" "potential prognostic unfavorable (1.76e-6)" "unprognostic (7.45e-2)" "unprognostic (1.98e-1)" "unprognostic (1.23e-2)" "unprognostic (8.23e-2)" "unprognostic (7.39e-2)" "unprognostic (3.37e-2)" "unprognostic (2.99e-3)" "unprognostic (4.31e-2)" "unprognostic (1.34e-1)" "unprognostic (3.81e-2)" "unprognostic (4.67e-3)" "unprognostic (6.97e-3)" "unprognostic (2.77e-1)" "unprognostic (1.01e-2)" "unprognostic (3.47e-1)" TEDDM1 "EDDM9, Epdd1, HE9, TMEM45C" ENSG00000203730 "Transmembrane epididymal protein 1" Q5T9Z0 1 182398117-182400667 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 527 "epididymis: 543.7" "Cell type enriched" "Detected in some" 85 "Epididymal principal cells: 822.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 15: Non-specific - Transcription" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" TEF KIAA1655 ENSG00000167074 "TEF transcription factor, PAR bZIP family member" Q10587 22 41367333-41399326 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 69.5;Myonuclei: 87.8;Retinal bipolar cells: 63.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 37: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 4 "unprognostic (3.09e-3)" "unprognostic (1.68e-1)" "unprognostic (2.57e-1)" "unprognostic (2.03e-1)" "unprognostic (6.88e-2)" "unprognostic (2.94e-1)" "unprognostic (1.06e-1)" "unprognostic (1.99e-2)" "unprognostic (2.34e-2)" "unprognostic (3.06e-1)" "validated prognostic favorable (1.29e-7)" "validated prognostic favorable (8.35e-4)" "potential prognostic favorable (1.77e-5)" "unprognostic (1.02e-1)" "unprognostic (1.85e-1)" "unprognostic (1.85e-2)" "unprognostic (1.44e-1)" "unprognostic (2.54e-1)" "unprognostic (5.94e-2)" "unprognostic (2.47e-2)" "unprognostic (4.02e-2)" "unprognostic (2.16e-2)" "unprognostic (2.23e-1)" "unprognostic (1.36e-2)" "unprognostic (2.80e-1)" "unprognostic (8.88e-3)" "unprognostic (8.06e-2)" "unprognostic (2.21e-2)" "unprognostic (1.30e-1)" "unprognostic (2.06e-1)" "unprognostic (3.72e-1)" TEFM "C17orf42, FLJ22729" ENSG00000172171 "Transcription elongation factor, mitochondrial" Q96QE5 17 30897336-30906238 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023788, HPA053044" Approved Enhanced Mitochondria No No "Cluster 33: Non-specific - ATP binding" "Cluster 76: Non-specific - Metabolism" "Cluster 31: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 7: Non-specific - Transcription" 16 Mitochondria "HPA023788: , HPA053044: " "unprognostic (5.96e-2)" "unprognostic (7.70e-3)" "unprognostic (2.41e-2)" "potential prognostic favorable (4.34e-4)" "unprognostic (6.30e-2)" "unprognostic (1.03e-1)" "unprognostic (6.69e-2)" "unprognostic (2.78e-1)" "unprognostic (2.72e-1)" "unprognostic (1.96e-3)" "unprognostic (1.40e-1)" "unprognostic (1.95e-3)" "potential prognostic unfavorable (9.74e-5)" "unprognostic (1.30e-2)" "unprognostic (3.03e-1)" "unprognostic (1.56e-2)" "unprognostic (5.17e-3)" "unprognostic (1.66e-1)" "unprognostic (5.03e-2)" "unprognostic (1.43e-1)" "unprognostic (1.19e-3)" "unprognostic (1.32e-1)" "unprognostic (2.08e-3)" "potential prognostic favorable (8.31e-5)" "unprognostic (7.93e-3)" "unprognostic (7.90e-2)" "unprognostic (9.82e-2)" "unprognostic (2.64e-1)" "unprognostic (2.90e-1)" TEK "CD202b, TIE-2, TIE2, VMCM, VMCM1" ENSG00000120156 "TEK receptor tyrosine kinase" Q02763 9 27109141-27230174 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Glaucoma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 43.5" "Group enriched" "Detected in many" 6 "Lymphatic endothelial cells: 124.0;Oligodendrocyte progenitor cells: 141.9;Vascular endothelial cells: 321.2" "Group enriched" "Detected in all" 8 "endothelial cell: 417.7;oligodendrocyte precursor cell: 143.8" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 13.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Rhabdoid: 17.5;testis cancer: 16.9" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Minor Salivary Gland - Endothelial cells, Pituitary gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Spleen - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010359, HPA073265" Approved Supported "Plasma membrane,Centrosome,Basal body" "Secreted to blood" Receptor NA NA 7750000 3100000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 14 "Plasma membrane" "Centrosome, Basal body" "CAB010359: , HPA073265: " "unprognostic (2.08e-1)" "unprognostic (3.02e-1)" "unprognostic (7.64e-3)" "unprognostic (4.21e-2)" "unprognostic (3.16e-2)" "unprognostic (5.78e-2)" "unprognostic (2.56e-1)" "unprognostic (8.83e-3)" "unprognostic (4.71e-3)" "unprognostic (3.04e-1)" "validated prognostic favorable (3.45e-13)" "validated prognostic favorable (5.48e-5)" "unprognostic (4.39e-3)" "validated prognostic favorable (1.01e-4)" "validated prognostic favorable (8.49e-4)" "unprognostic (2.27e-2)" "unprognostic (3.43e-2)" "unprognostic (6.68e-2)" "unprognostic (1.65e-1)" "unprognostic (1.82e-1)" "unprognostic (7.71e-2)" "unprognostic (1.10e-2)" "unprognostic (1.11e-1)" "unprognostic (1.48e-1)" "unprognostic (6.37e-2)" "unprognostic (1.74e-2)" "unprognostic (3.60e-3)" "unprognostic (3.71e-2)" "unprognostic (5.25e-2)" "unprognostic (6.63e-2)" TEKT1 ENSG00000167858 "Tektin 1" Q969V4 17 6789133-6831761 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "choroid plexus: 41.7;fallopian tube: 47.4" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 146.3;Early spermatids: 455.1;Endometrial ciliated cells: 323.9;Ependymal cells: 493.7;Epididymal efferent duct ciliated cells: 476.8;Fallopian tube ciliated cells: 593.6;Late primary spermatocytes: 301.7;Late spermatids: 184.2;Respiratory ciliated cells: 674.2" "Cell type enriched" "Detected in many" 4 "ependymal cell: 512.4" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 10.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "midbrain: 10.5" "HPA044444, HPA062285" Approved NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 107: Ciliated cells - Cilia assembly & function" 23 "HPA044444: , HPA062285: " "unprognostic (4.35e-1)" "unprognostic (5.25e-3)" "unprognostic (1.28e-1)" "unprognostic (1.34e-2)" "unprognostic (2.46e-1)" "unprognostic (1.99e-1)" "unprognostic (8.79e-2)" "unprognostic (2.16e-1)" "unprognostic (5.82e-3)" "unprognostic (1.49e-2)" "unprognostic (2.26e-1)" TEKT2 TEKTB1 ENSG00000092850 "Tektin 2" Q9UIF3 1 36084094-36088275 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "choroid plexus: 27.0;fallopian tube: 59.0;testis: 68.7" "Cell type enhanced" "Detected in some" "Early spermatids: 567.2;Endometrial ciliated cells: 85.0;Epididymal efferent duct ciliated cells: 90.2;Fallopian tube ciliated cells: 249.8;Late primary spermatocytes: 278.0;Late spermatids: 457.6;Respiratory ciliated cells: 198.8" "Group enriched" "Detected in some" 14 "choroid plexus epithelial cell: 9.2;ependymal cell: 32.9" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 18.8" "Region enhanced" "Detected in all" "choroid plexus: 23.9" "Immune cell enriched" "Detected in single" 13 "neutrophil: 1.2" "Lineage enriched" "Detected in single" 13 "granulocytes: 1.2" "Cancer enhanced" "Detected in some" "Bone cancer: 3.2" "Adipose visceral - Mesothelial cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA027461 Approved Supported "Connecting piece,Flagellar centriole,Mid piece,Principal piece" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" 9 "Connecting piece" "Flagellar centriole, Mid piece, Principal piece" "HPA027461: " "unprognostic (1.52e-1)" "unprognostic (1.31e-2)" "unprognostic (1.56e-1)" "unprognostic (7.32e-3)" "unprognostic (3.70e-1)" "unprognostic (2.58e-1)" "potential prognostic favorable (1.87e-5)" "unprognostic (6.87e-2)" "potential prognostic favorable (1.66e-4)" "unprognostic (6.56e-3)" "unprognostic (2.28e-1)" "unprognostic (5.74e-2)" "unprognostic (3.65e-2)" "unprognostic (3.22e-3)" "unprognostic (2.37e-3)" "unprognostic (4.03e-3)" "unprognostic (5.53e-2)" "unprognostic (5.27e-3)" "unprognostic (1.12e-1)" TEKT3 FLJ32828 ENSG00000125409 "Tektin 3" Q9BXF9 17 15303811-15341632 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 29.9" "Group enriched" "Detected in many" 5 "Early spermatids: 520.4;Late primary spermatocytes: 227.3;Late spermatids: 574.9" "Cell type enriched" "Detected in many" 7 "ependymal cell: 52.3" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 2.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.7" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.7" "Cancer enriched" "Detected in single" 7 "testis cancer: 2.5" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA044354, HPA073565" Enhanced Supported "Equatorial segment,Calyx,Mid piece,Principal piece,End piece" NA NA "Cluster 47: Testis - Mixed function" "Cluster 17: Choroid plexus - Cilium" "Cluster 55: Lymphoma - Immune response" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 28 "Mid piece, Principal piece, End piece" "Equatorial segment, Calyx" "HPA044354: , HPA073565: " "unprognostic (3.04e-1)" "potential prognostic unfavorable (1.97e-4)" "unprognostic (2.98e-1)" "unprognostic (1.96e-1)" TEKT4 MGC27019 ENSG00000163060 "Tektin 4" Q8WW24 2 94871430-94876823 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 12.8" "Group enriched" "Detected in some" 19 "Early spermatids: 132.0;Endometrial ciliated cells: 49.0;Ependymal cells: 45.4;Epididymal efferent duct ciliated cells: 57.1;Fallopian tube ciliated cells: 71.6;Late primary spermatocytes: 98.5;Late spermatids: 172.3;Respiratory ciliated cells: 87.4" "Cell type enriched" "Detected in some" 25 "ependymal cell: 56.4" "Cancer enhanced" "Detected in single" "Uterine Corpus Endometrial Carcinoma (TCGA): 3.3" "Region enhanced" "Detected in some" "midbrain: 3.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Region enhanced" "Detected in some" "midbrain: 3.9" "HPA048600, HPA069872" Enhanced Supported "Perinuclear theca,Connecting piece,Flagellar centriole,Principal piece,End piece,Annulus" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 107: Ciliated cells - Cilia assembly & function" 85 "Perinuclear theca, Connecting piece, Flagellar centriole, Principal piece, End piece, Annulus" "HPA048600: , HPA069872: " "unprognostic (7.95e-2)" "unprognostic (1.04e-1)" TEKT5 "CT149, FLJ32871" ENSG00000153060 "Tektin 5" Q96M29 16 10627501-10694930 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 32 "testis: 30.4" "Group enriched" "Detected in many" 7 "Early spermatids: 772.3;Late spermatids: 237.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Outer root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA043578 Uncertain "Actin filaments" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 51: Neurons - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 28 "Actin filaments" "HPA043578: " "unprognostic (3.87e-2)" "unprognostic (3.73e-1)" "unprognostic (1.23e-1)" TEKTIP1 "C19orf71, LOC100128569" ENSG00000183397 "Tektin bundle interacting protein 1" A6NCJ1 19 3539171-3544030 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 47.9" "Group enriched" "Detected in many" 7 "Early spermatids: 788.7;Late spermatids: 537.7" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 29.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in all" 6 "skin cancer: 150.5" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA048654 Uncertain Approved "Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA "Cluster 47: Testis - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 69: Skin cancer - ECM organization" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" "Plasma membrane, Cytosol" "Endoplasmic reticulum" "HPA048654: " "unprognostic (3.12e-2)" "unprognostic (4.04e-2)" "unprognostic (2.23e-3)" "unprognostic (2.11e-1)" "unprognostic (5.03e-2)" "unprognostic (5.11e-2)" "unprognostic (1.93e-1)" "unprognostic (8.01e-2)" "potential prognostic favorable (4.05e-4)" "unprognostic (8.11e-3)" "unprognostic (6.13e-3)" "unprognostic (2.58e-2)" "unprognostic (2.46e-3)" "unprognostic (3.78e-1)" "unprognostic (1.21e-2)" "unprognostic (1.21e-1)" "unprognostic (2.27e-1)" "unprognostic (4.05e-2)" "unprognostic (7.99e-3)" "unprognostic (1.24e-1)" "potential prognostic favorable (6.66e-5)" "unprognostic (2.08e-1)" "unprognostic (9.81e-2)" "unprognostic (1.12e-1)" "unprognostic (8.21e-2)" "unprognostic (2.35e-2)" "unprognostic (5.88e-3)" "unprognostic (1.09e-1)" "unprognostic (3.47e-2)" "unprognostic (3.66e-2)" TELO2 "hCLK2, KIAA0683, TEL2" ENSG00000100726 "Telomere maintenance 2" Q9Y4R8 16 1493344-1510457 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041348, HPA041473" Approved Supported "Nuclear bodies,Cytosol" NA NA 9300 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 64: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 54: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 44 "Nuclear bodies, Cytosol" "HPA041348: , HPA041473: " "unprognostic (3.83e-1)" "unprognostic (5.07e-2)" "unprognostic (1.75e-1)" "unprognostic (2.92e-1)" "unprognostic (3.73e-2)" "unprognostic (3.68e-3)" "unprognostic (2.65e-1)" "unprognostic (1.77e-2)" "unprognostic (5.20e-3)" "unprognostic (7.16e-2)" "unprognostic (2.64e-1)" "unprognostic (9.09e-2)" "unprognostic (7.13e-2)" "unprognostic (1.10e-2)" "unprognostic (1.98e-1)" "unprognostic (2.05e-1)" "unprognostic (7.70e-2)" "unprognostic (1.68e-1)" "unprognostic (4.45e-2)" "unprognostic (1.98e-1)" "unprognostic (5.14e-3)" "unprognostic (1.43e-2)" "unprognostic (1.33e-2)" "unprognostic (1.41e-2)" "unprognostic (1.14e-3)" "unprognostic (1.66e-2)" "unprognostic (7.51e-2)" "unprognostic (4.27e-2)" "unprognostic (2.89e-1)" "unprognostic (1.13e-1)" "unprognostic (2.30e-1)" TEN1 "C17orf106, FLJ39785" ENSG00000257949 "TEN1 subunit of CST complex" Q86WV5 17 75979240-76000586 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Bergmann glia: 3.0;Brain excitatory neurons: 2.6;Brain inhibitory neurons: 2.5;Choroid plexus epithelial cells: 5.8;Distal convoluted tubule cells: 5.5;Ependymal cells: 3.0;Loop of henle epithelial cells: 6.7;Microglia: 4.0;Oligodendrocytes: 3.6;Other brain neurons: 4.7;Papillary tip epithelial cells: 7.7;Podocytes: 5.2;Proximal tubule cells: 11.6;Renal collecting duct intercalated cells: 6.9;Renal collecting duct principal cells: 5.6;Renal connecting tubule cells: 6.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065069 Supported Nucleoplasm NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 88: Proximal tubular cells - Transmembrane transport" 18 Nucleoplasm "HPA065069: " "unprognostic (1.37e-1)" "unprognostic (3.52e-2)" "unprognostic (3.46e-1)" "unprognostic (1.27e-1)" "unprognostic (5.60e-2)" "unprognostic (2.47e-2)" "unprognostic (6.93e-2)" "potential prognostic unfavorable (8.73e-4)" "unprognostic (3.26e-2)" "unprognostic (7.74e-3)" "unprognostic (1.46e-1)" "unprognostic (1.48e-3)" "unprognostic (8.80e-2)" "unprognostic (1.57e-1)" "unprognostic (3.46e-2)" "unprognostic (4.22e-2)" "unprognostic (1.22e-1)" "unprognostic (8.90e-2)" "unprognostic (4.72e-2)" "unprognostic (1.56e-2)" "unprognostic (3.36e-1)" "unprognostic (1.08e-1)" "unprognostic (1.57e-3)" "unprognostic (5.37e-2)" "unprognostic (1.44e-2)" "unprognostic (9.06e-2)" "unprognostic (1.12e-2)" "unprognostic (3.12e-1)" "unprognostic (3.05e-1)" TENM1 "ODZ1, ODZ3, TEN-M1, TEN1, TNM" ENSG00000009694 "Teneurin transmembrane protein 1" Q9UKZ4 X 124375903-125204312 "Predicted membrane proteins, Transporters" "Stress response, Transcription, Transcription regulation" "Neuropeptide, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.1" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 329.7;Bergmann glia: 259.8;Brain excitatory neurons: 324.6;Corticotrophs: 433.0;Fibro-adipogenic progenitors: 242.5;Lactotrophs: 599.5;Neutrophils: 1060.0;Oligodendrocyte progenitor cells: 295.1;Pituicytes/FSCs: 250.8;Pituitary stem cells: 327.7;Prostatic glandular cells: 1397.2;Retinal amacrine cells: 437.5;Somatotrophs: 307.3" "Cell type enhanced" "Detected in all" "upper rhombic lip: 821.9" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 9.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Gallbladder cancer: 41.4" "Adrenal gland - Adrenal medulla cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002848, HPA063910" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 35: Non-specific - DNA binding" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 2 "Nucleoplasm, Plasma membrane" "HPA002848: , HPA063910: " "unprognostic (9.62e-2)" "unprognostic (6.57e-2)" "unprognostic (2.09e-3)" "unprognostic (3.83e-2)" "unprognostic (3.99e-3)" "potential prognostic favorable (9.49e-4)" "unprognostic (2.04e-3)" "unprognostic (2.53e-1)" "unprognostic (7.83e-2)" "unprognostic (4.07e-3)" TENM2 "KIAA1127, ODZ2, Ten-M2, TEN2" ENSG00000145934 "Teneurin transmembrane protein 2" Q9NT68 5 166979029-168264157 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "heart muscle: 32.8" "Cell type enhanced" "Detected in many" "Astrocytes: 890.1;Bergmann glia: 873.8;Brain excitatory neurons: 1896.6;Brain inhibitory neurons: 1690.2;Cardiomyocytes: 730.4;Choroid plexus epithelial cells: 1452.1;Medullary thymic epithelial cells: 684.1;Other brain neurons: 1167.8;Peritubular myoid cells: 621.7;Podocytes: 873.2;Retinal amacrine cells: 1215.6;Retinal ganglion cells: 1672.6;Retinal horizontal cells: 2708.6;Thymic myoid cells: 1352.8" "Cell type enhanced" "Detected in all" "mammillary body: 6183.6" "Group enriched" "Detected in many" 5 "Head and Neck Squamous Cell Carcinoma (TCGA): 25.7;Lung Squamous Cell Carcinoma (TCGA): 8.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 25.6;Brain cancer: 25.6" "Heart muscle - Cardiomyocytes, Kidney - Podocytes, Prostate - Smooth muscle cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038018, HPA038420, HPA068691" Uncertain Approved Nucleoli No No 21000 "Cluster 35: Non-specific - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 109: Neurons - Neuronal signaling" Nucleoli "HPA038018: , HPA038420: , HPA068691: " "unprognostic (1.38e-2)" "unprognostic (2.06e-1)" "unprognostic (3.50e-1)" "unprognostic (1.12e-2)" "unprognostic (3.34e-1)" "unprognostic (6.77e-3)" "unprognostic (5.37e-2)" "unprognostic (3.68e-2)" "unprognostic (1.18e-1)" "unprognostic (3.29e-2)" TENM3 "KIAA1455, ODZ3, Ten-M3, TEN3" ENSG00000218336 "Teneurin transmembrane protein 3" Q9P273 4 182143987-182803024 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Differentiation" "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 12.3" "Cell type enhanced" "Detected in many" "Adipocytes: 865.8;Adrenal cortex cells: 1330.7;Brain inhibitory neurons: 577.3;Cytotrophoblasts: 2024.1;Extravillous trophoblasts: 598.8;Migrating cytotrophoblasts: 1233.6;Pituicytes/FSCs: 1089.8;Pituitary stem cells: 1229.5;Podocytes: 821.0;Retinal bipolar cells: 746.0;Schwann cells: 597.3;Syncytiotrophoblasts: 1526.6;Thymic myoid cells: 776.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Lung - Fibroblasts_2, Prostate - Smooth muscle cells, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047043, HPA070233" Approved Approved "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 51: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 1 Nucleoplasm "Cell Junctions, Cytosol" "HPA047043: , HPA070233: " "unprognostic (1.62e-1)" "unprognostic (6.50e-2)" "unprognostic (1.73e-1)" "unprognostic (3.39e-2)" "unprognostic (2.30e-1)" "unprognostic (4.92e-2)" "unprognostic (3.29e-2)" "unprognostic (2.03e-3)" "unprognostic (1.60e-2)" "unprognostic (1.82e-1)" "unprognostic (2.13e-2)" "unprognostic (1.14e-1)" "unprognostic (1.61e-1)" "unprognostic (2.45e-1)" "unprognostic (2.00e-2)" "potential prognostic unfavorable (3.94e-5)" "unprognostic (3.57e-2)" "unprognostic (2.15e-1)" "unprognostic (1.67e-1)" "unprognostic (6.97e-2)" "unprognostic (1.51e-1)" "unprognostic (1.97e-3)" "unprognostic (1.65e-1)" "unprognostic (5.23e-3)" "unprognostic (2.69e-1)" TENM4 "DOC4, KIAA1302, ODZ4, Ten-M4, TEN4" ENSG00000149256 "Teneurin transmembrane protein 4" Q6N022 11 78652829-79441030 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Differentiation "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 14.8;parathyroid gland: 13.1" "Cell type enhanced" "Detected in many" "Adipocytes: 403.0;Brain excitatory neurons: 354.4;Brain inhibitory neurons: 390.6;Gonadotrophs: 360.2;Lactotrophs: 596.4;Microglia: 428.4;Myosatellite cells: 347.3;Pituitary stem cells: 1692.3;Retinal amacrine cells: 652.4;Retinal ganglion cells: 788.0;Thyrotrophs: 650.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 36.0" "Colon - Enteric glia cells, Pituitary gland - Lactotropes, Skeletal muscle - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019521, HPA065961" Approved NA NA "Cluster 75: Ovary - Mixed function" "Cluster 22: Non-specific - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" 7 "HPA019521: , HPA065961: " "unprognostic (3.04e-1)" "unprognostic (1.48e-1)" "unprognostic (3.63e-1)" "unprognostic (2.27e-1)" "unprognostic (1.01e-1)" "unprognostic (1.86e-2)" "unprognostic (3.30e-1)" "unprognostic (1.16e-2)" "unprognostic (1.36e-2)" "unprognostic (2.26e-1)" "unprognostic (1.20e-1)" "unprognostic (7.72e-2)" "unprognostic (1.05e-2)" "potential prognostic favorable (5.25e-4)" "unprognostic (2.41e-2)" "unprognostic (2.06e-2)" "unprognostic (3.39e-2)" "unprognostic (3.76e-2)" "unprognostic (7.13e-2)" "unprognostic (1.85e-2)" "unprognostic (2.75e-1)" "unprognostic (1.01e-2)" "unprognostic (1.26e-1)" "unprognostic (4.42e-2)" "unprognostic (2.72e-2)" TENT2 "FLJ38499, GLD2, PAPD4, TUT2" ENSG00000164329 "Terminal nucleotidyltransferase 2" Q6PIY7 5 79612120-79688246 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "mRNA processing" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054468 Approved Cytosol No No "Cluster 35: Neutrophils - Protein binding" "Cluster 15: Bone marrow - Innate immune response" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 5 Cytosol "HPA054468: " "potential prognostic favorable (3.49e-4)" "unprognostic (1.87e-1)" "unprognostic (2.97e-2)" "unprognostic (4.09e-2)" "unprognostic (9.27e-2)" "unprognostic (2.24e-1)" "unprognostic (3.29e-1)" "unprognostic (1.03e-2)" "unprognostic (1.45e-3)" "unprognostic (1.13e-3)" "unprognostic (1.03e-2)" "unprognostic (3.02e-2)" "unprognostic (1.41e-2)" "unprognostic (1.25e-1)" "unprognostic (8.70e-3)" "unprognostic (3.57e-1)" "unprognostic (1.49e-1)" "unprognostic (6.06e-3)" "unprognostic (1.64e-2)" "unprognostic (1.48e-1)" "unprognostic (1.92e-3)" "unprognostic (1.48e-1)" "unprognostic (8.41e-2)" "unprognostic (1.79e-1)" "unprognostic (2.69e-2)" "unprognostic (9.00e-2)" "unprognostic (1.91e-1)" "unprognostic (6.34e-3)" "unprognostic (1.57e-1)" TENT4A "LAK-1, PAPD7, POLK, POLS, TRF4, TRF4-1" ENSG00000112941 "Terminal nucleotidyltransferase 4A" Q5XG87 5 6713432-6757044 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045487, HPA046742" Enhanced Supported "Nucleoplasm,Nuclear membrane,Golgi apparatus" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 15: Bone marrow - Innate immune response" "Cluster 2: Neurons - Nucleosome" "Cluster 29: Non-specific - Unknown function" "Cluster 82: Dendritic cells - Antigen presentation" 1 Nucleoplasm "Nuclear membrane, Golgi apparatus" "HPA045487: , HPA046742: " "unprognostic (2.12e-1)" "unprognostic (1.47e-2)" "unprognostic (1.36e-1)" "unprognostic (9.47e-2)" "unprognostic (2.14e-1)" "unprognostic (1.38e-1)" "unprognostic (7.14e-2)" "unprognostic (3.95e-3)" "unprognostic (3.77e-2)" "unprognostic (4.51e-1)" "unprognostic (1.76e-1)" "unprognostic (7.98e-2)" "unprognostic (6.59e-2)" "unprognostic (2.09e-1)" "potential prognostic unfavorable (9.51e-4)" "unprognostic (2.16e-1)" "potential prognostic favorable (5.64e-4)" "unprognostic (2.56e-1)" "unprognostic (1.08e-2)" "unprognostic (4.32e-2)" "potential prognostic unfavorable (6.62e-4)" "unprognostic (7.16e-2)" "unprognostic (1.09e-1)" "unprognostic (4.31e-1)" "unprognostic (4.03e-1)" "unprognostic (3.76e-1)" "unprognostic (3.66e-1)" "unprognostic (3.36e-2)" "unprognostic (1.48e-3)" TENT4B "PAPD5, TRF4-2, TUT3" ENSG00000121274 "Terminal nucleotidyltransferase 4B" Q8NDF8 16 50152911-50235310 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, mRNA processing, rRNA processing" "Nucleotidyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "NK-cells: 212.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042968, HPA048225" Uncertain Supported "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 2 Cytosol "Nucleoli, Plasma membrane" "HPA042968: , HPA048225: " "unprognostic (1.63e-2)" "unprognostic (6.55e-2)" "unprognostic (1.69e-2)" "unprognostic (6.58e-2)" "unprognostic (9.02e-2)" "unprognostic (2.14e-2)" "unprognostic (1.32e-1)" "unprognostic (3.90e-2)" "potential prognostic favorable (2.17e-4)" "unprognostic (1.15e-1)" "unprognostic (5.57e-2)" "unprognostic (1.64e-1)" "unprognostic (1.44e-1)" "unprognostic (4.07e-2)" "unprognostic (1.61e-1)" "unprognostic (1.83e-2)" "unprognostic (2.74e-3)" "unprognostic (1.65e-1)" "unprognostic (1.90e-2)" "unprognostic (2.29e-1)" "unprognostic (3.24e-3)" "unprognostic (2.55e-2)" "unprognostic (3.12e-1)" "unprognostic (1.94e-1)" "unprognostic (1.98e-1)" "unprognostic (4.88e-2)" "unprognostic (1.57e-1)" TENT5A "C6orf37, FAM46A, FLJ20037" ENSG00000112773 "Terminal nucleotidyltransferase 5A" Q96IP4 6 81491439-81752774 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 213.3;salivary gland: 98.3" "Cell type enhanced" "Detected in many" "Foveolar cells: 376.5;Lacrimal acinar cells: 630.5;Mast cells: 379.8;Neutrophil progenitors: 508.0" "Cell type enhanced" "Detected in many" "Bergmann glia: 327.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Kidney - Fibroblasts, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA051067, HPA067140" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 14 Nucleoplasm Cytosol "HPA051067: , HPA067140: " "unprognostic (8.85e-2)" "unprognostic (2.40e-1)" "unprognostic (2.17e-2)" "unprognostic (2.78e-3)" "unprognostic (5.93e-2)" "unprognostic (1.28e-1)" "unprognostic (4.59e-2)" "unprognostic (1.66e-2)" "unprognostic (5.78e-3)" "unprognostic (3.89e-3)" "unprognostic (2.26e-1)" "unprognostic (9.67e-2)" "unprognostic (8.40e-2)" "unprognostic (1.96e-2)" "unprognostic (1.28e-1)" "unprognostic (2.45e-3)" "unprognostic (1.21e-2)" "unprognostic (2.79e-1)" "unprognostic (2.25e-1)" "unprognostic (5.79e-3)" "unprognostic (4.61e-2)" "unprognostic (2.88e-1)" "unprognostic (2.07e-1)" "unprognostic (4.46e-2)" "unprognostic (7.29e-2)" "unprognostic (4.65e-2)" "unprognostic (3.90e-2)" "unprognostic (1.09e-1)" "unprognostic (9.94e-3)" TENT5B "FAM46B, MGC16491" ENSG00000158246 "Terminal nucleotidyltransferase 5B" Q96A09 1 27005020-27012850 "Enzymes, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 107.7;skin 1: 115.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 117.2;Basal keratinocytes: 100.2;Esophageal apical cells: 380.1;Esophageal basal cells: 79.3;Esophageal suprabasal cells: 261.8;Lacrimal acinar cells: 71.6;Suprabasal keratinocytes: 192.8" "Cell type enriched" "Detected in some" 8 "vascular associated smooth muscle cell: 9.6" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 128.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Adrenal gland - Smooth muscle cells, Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Smooth muscle cells, Spleen - Smooth muscle cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 37: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 64 "unprognostic (3.70e-2)" "unprognostic (5.06e-3)" "unprognostic (6.34e-3)" "unprognostic (1.61e-1)" "unprognostic (1.66e-1)" "unprognostic (2.01e-2)" "unprognostic (3.25e-3)" "unprognostic (3.20e-2)" "unprognostic (1.44e-1)" "unprognostic (1.68e-1)" "unprognostic (3.31e-2)" "unprognostic (3.45e-1)" "unprognostic (1.31e-2)" "unprognostic (4.29e-3)" "unprognostic (7.20e-2)" "potential prognostic unfavorable (7.51e-4)" "unprognostic (3.54e-2)" "unprognostic (5.91e-2)" "unprognostic (2.89e-1)" "unprognostic (9.27e-2)" "unprognostic (2.52e-3)" "unprognostic (3.83e-1)" "unprognostic (7.02e-2)" "unprognostic (1.13e-1)" "unprognostic (2.30e-2)" "unprognostic (7.98e-2)" TENT5C "FAM46C, FLJ20202" ENSG00000183508 "Terminal nucleotidyltransferase 5C" Q5VWP2 1 117606048-117628389 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Host-virus interaction" "Nucleotidyltransferase, RNA-binding, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 84.0" "Cell type enhanced" "Detected in many" "Early spermatids: 562.7;Erythrocytes: 315.6;Late spermatids: 2755.6;Plasma cells: 737.7;Platelets: 251.4" "Group enriched" "Detected in some" 4 "choroid plexus epithelial cell: 57.5;leukocyte: 94.5" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 14 "choroid plexus: 57.0" "Immune cell enhanced" "Detected in many" "basophil: 29.5" "Group enriched" "Detected in many" 17 "B-cells: 13.4;granulocytes: 29.5;T-cells: 13.7" "Cancer enriched" "Detected in many" 8 "Myeloma: 126.2" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA054049 Uncertain Supported Nucleoplasm NA NA "Cluster 32: Basophils - Transcription" "Cluster 21: Testis - Mixed function" "Cluster 36: Choroid plexus - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 2 Nucleoplasm "HPA054049: " "unprognostic (2.91e-2)" "unprognostic (2.20e-1)" "unprognostic (1.86e-2)" "unprognostic (4.36e-2)" "unprognostic (1.76e-1)" "unprognostic (1.51e-1)" "unprognostic (1.71e-3)" "unprognostic (4.35e-2)" "potential prognostic favorable (6.70e-6)" "unprognostic (1.96e-2)" "unprognostic (2.41e-2)" "unprognostic (1.69e-1)" "potential prognostic favorable (4.84e-5)" "unprognostic (2.07e-2)" "unprognostic (3.05e-2)" "unprognostic (3.75e-1)" "unprognostic (1.32e-2)" "unprognostic (2.16e-1)" "unprognostic (5.24e-3)" "unprognostic (1.08e-3)" "unprognostic (5.68e-2)" "unprognostic (1.01e-2)" "unprognostic (2.78e-1)" "unprognostic (1.12e-1)" "unprognostic (1.08e-1)" "unprognostic (3.46e-2)" "unprognostic (3.63e-2)" "unprognostic (8.65e-2)" TENT5D "CT1.26, CT112, FAM46D, MGC26999" ENSG00000174016 "Terminal nucleotidyltransferase 5D" Q8NEK8 X 80335504-80445311 "Enzymes, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 32 "testis: 3.2" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 10.6;Early primary spermatocytes: 7.9;Early spermatids: 18.3;Late primary spermatocytes: 30.0;Pituitary stem cells: 6.1;Sertoli cells: 7.0;Undifferentiated spermatogonia: 14.7" "Cell type enhanced" "Detected in some" "committed oligodendrocyte precursor: 2.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA059362 Uncertain NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 47: Leukemia - Hemostasis" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" 15 "HPA059362: " TEP1 "p240, TLP1, TP1, TROVE1, VAULT2" ENSG00000129566 "Telomerase associated protein 1" Q99973 14 20365667-20413501 "Plasma proteins, Predicted intracellular proteins" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Foveolar cells: 55.7" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 70.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA029206 Approved Nucleoplasm,Vesicles NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 77: Intestine - Digestion" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 7 Nucleoplasm Vesicles "HPA029206: " "unprognostic (9.04e-2)" "unprognostic (1.23e-1)" "unprognostic (2.58e-1)" "unprognostic (1.03e-3)" "unprognostic (1.78e-1)" "unprognostic (1.82e-1)" "unprognostic (1.32e-1)" "unprognostic (1.36e-1)" "unprognostic (1.77e-2)" "unprognostic (5.97e-2)" "unprognostic (6.45e-3)" "unprognostic (2.55e-2)" "unprognostic (1.21e-1)" "unprognostic (4.35e-3)" "unprognostic (4.98e-2)" "unprognostic (3.90e-2)" "unprognostic (6.88e-2)" "unprognostic (4.85e-2)" "unprognostic (1.49e-2)" "unprognostic (3.36e-2)" "unprognostic (3.88e-2)" "unprognostic (3.30e-2)" "unprognostic (1.47e-1)" "unprognostic (3.12e-1)" "unprognostic (7.61e-2)" "unprognostic (1.22e-1)" "unprognostic (3.03e-1)" "unprognostic (5.61e-2)" "unprognostic (1.62e-1)" "unprognostic (8.88e-2)" "unprognostic (8.34e-2)" TEPP ENSG00000159648 "Testis, prostate and placenta expressed" Q6URK8 16 57976435-57988116 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 9.6" "Group enriched" "Detected in many" 6 "Early spermatids: 469.7;Late spermatids: 594.7" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Bladder Urothelial Carcinoma (TCGA): 2.7;Thyroid Carcinoma (TCGA): 5.3" "Not detected" "Not detected" "Low immune cell specificity" "Detected in single" "Lineage enriched" "Detected in single" 6 "T-cells: 1.3" "Not detected" "Not detected" "Breast - Breast myoepithelial cells, Testis - Late spermatids" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA062092 Enhanced NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 1 "HPA062092: " "unprognostic (1.88e-3)" "unprognostic (1.35e-3)" "unprognostic (9.06e-3)" TEPSIN "C17orf56, ENTHD2, FLJ31528" ENSG00000167302 "TEPSIN adaptor related protein complex 4 accessory protein" Q96N21 17 81228277-81239091 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Tuft cells: 46.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024683 Supported Vesicles NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 27: Breast cancer - Unknown function" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 109 Vesicles "HPA024683: " "unprognostic (4.95e-2)" "unprognostic (6.19e-3)" "unprognostic (3.59e-2)" "unprognostic (2.00e-1)" "unprognostic (8.68e-2)" "unprognostic (1.19e-2)" "unprognostic (6.24e-2)" "unprognostic (4.88e-3)" "unprognostic (6.32e-2)" "potential prognostic unfavorable (5.92e-7)" "unprognostic (1.79e-3)" "unprognostic (2.67e-1)" "potential prognostic unfavorable (1.17e-5)" "unprognostic (1.53e-1)" "unprognostic (7.07e-2)" "unprognostic (1.88e-1)" "unprognostic (6.03e-3)" "unprognostic (1.90e-1)" "potential prognostic favorable (9.01e-4)" "potential prognostic favorable (6.56e-4)" "unprognostic (2.47e-2)" "unprognostic (2.11e-1)" "unprognostic (1.97e-1)" "unprognostic (2.08e-1)" "unprognostic (4.01e-1)" "unprognostic (3.05e-1)" "unprognostic (2.27e-1)" "unprognostic (4.66e-1)" "unprognostic (3.63e-2)" TERB1 "CCDC79, FLJ35894" ENSG00000249961 "Telomere repeat binding bouquet formation protein 1" Q8NA31 16 66754640-66801620 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Meiosis "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 11.7" "Cell type enriched" "Detected in many" 6 "Early primary spermatocytes: 369.8" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 6.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.8" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.8" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA079436 Approved "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 48: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 3: Early primary spermatocytes - Early meiosis" 1 Nucleoplasm "Cell Junctions, Cytosol" "HPA079436: " "unprognostic (3.15e-2)" "unprognostic (7.39e-2)" "unprognostic (2.48e-1)" "potential prognostic unfavorable (3.49e-4)" "unprognostic (1.52e-1)" "unprognostic (2.46e-2)" "unprognostic (4.79e-2)" "unprognostic (1.09e-1)" "unprognostic (2.70e-1)" "unprognostic (6.37e-2)" TERB2 "C15orf43, MGC33951" ENSG00000167014 "Telomere repeat binding bouquet formation protein 2" Q8NHR7 15 44956687-44979229 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "testis: 20.5" "Group enriched" "Detected in some" 8 "Early primary spermatocytes: 118.6;Late primary spermatocytes: 243.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes, Skin - Sebaceous gland cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA041780 Uncertain Nucleoplasm,Nucleoli No NA "Cluster 57: Testis - Spermatogenesis" "Cluster 18: Liver cancer - Metabolism" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" Nucleoli Nucleoplasm "HPA041780: " TERF1 "PIN2, TRBF1, TRF, TRF1" ENSG00000147601 "Telomeric repeat binding factor 1" P54274 8 73008856-73048123 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 180.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048379 Approved "Nucleoli fibrillar center,Nuclear bodies" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 65: Brain - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 94: Gonadal somatic cells - Mixed function" 108 "Nucleoli fibrillar center" "Nuclear bodies" "HPA048379: " "unprognostic (3.47e-1)" "unprognostic (6.65e-3)" "unprognostic (3.49e-1)" "unprognostic (1.73e-1)" "unprognostic (1.13e-1)" "unprognostic (2.40e-2)" "unprognostic (1.75e-1)" "unprognostic (1.14e-1)" "unprognostic (3.05e-1)" "unprognostic (3.20e-2)" "potential prognostic favorable (2.10e-6)" "unprognostic (7.05e-2)" "unprognostic (5.34e-3)" "unprognostic (2.90e-1)" "unprognostic (6.39e-2)" "unprognostic (4.36e-2)" "unprognostic (1.01e-1)" "unprognostic (7.10e-2)" "unprognostic (2.19e-2)" "unprognostic (7.51e-3)" "unprognostic (4.03e-2)" "unprognostic (5.57e-2)" "unprognostic (2.05e-3)" "unprognostic (7.06e-2)" "unprognostic (4.59e-2)" "unprognostic (1.11e-1)" "unprognostic (7.16e-2)" "unprognostic (8.68e-2)" "unprognostic (8.30e-2)" "unprognostic (8.91e-2)" "unprognostic (2.24e-1)" TERF2 "TRBF2, TRF2" ENSG00000132604 "Telomeric repeat binding factor 2" Q15554 16 69355567-69408571 "Essential proteins, Predicted intracellular proteins" "Cell cycle" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001907, HPA002735, CAB010451, CAB080271" Enhanced Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 27: Cerebellum - Synaptic function" "Cluster 34: Non-specific - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Transcription" 90 "Nucleoplasm, Nuclear bodies" "CAB010451: , CAB080271: , HPA001907: , HPA002735: " "unprognostic (3.31e-3)" "unprognostic (3.10e-2)" "unprognostic (1.39e-1)" "unprognostic (7.75e-2)" "unprognostic (1.37e-1)" "unprognostic (2.75e-2)" "unprognostic (1.72e-1)" "unprognostic (4.27e-3)" "unprognostic (9.46e-2)" "unprognostic (4.58e-3)" "validated prognostic favorable (3.08e-4)" "validated prognostic favorable (7.99e-4)" "unprognostic (1.86e-1)" "unprognostic (6.24e-3)" "unprognostic (1.18e-1)" "unprognostic (1.38e-1)" "unprognostic (5.61e-3)" "unprognostic (2.62e-2)" "unprognostic (7.81e-3)" "unprognostic (1.08e-1)" "unprognostic (6.40e-3)" "unprognostic (2.57e-1)" "unprognostic (5.30e-2)" "unprognostic (9.41e-3)" "unprognostic (1.20e-1)" "unprognostic (2.77e-1)" "unprognostic (5.29e-2)" "unprognostic (1.31e-1)" "unprognostic (2.87e-1)" "unprognostic (9.38e-3)" "unprognostic (1.83e-2)" TERF2IP RAP1 ENSG00000166848 "TERF2 interacting protein" Q9NYB0 16 75647773-75761872 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pancreas - Endothelial cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006580, HPA006719, CAB018660, CAB018749" Supported Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 125 "Nucleoplasm, Nuclear bodies" "CAB018660: , CAB018749: , HPA006580: , HPA006719: " "unprognostic (4.51e-2)" "unprognostic (3.92e-2)" "unprognostic (1.92e-1)" "unprognostic (1.20e-1)" "unprognostic (2.08e-2)" "unprognostic (1.48e-3)" "unprognostic (3.63e-1)" "unprognostic (2.04e-2)" "unprognostic (2.76e-3)" "unprognostic (7.73e-2)" "unprognostic (1.14e-3)" "unprognostic (2.56e-2)" "unprognostic (1.38e-2)" "unprognostic (9.38e-2)" "unprognostic (3.69e-2)" "unprognostic (5.78e-2)" "unprognostic (9.09e-2)" "unprognostic (2.24e-1)" "unprognostic (2.32e-1)" "unprognostic (7.02e-2)" "unprognostic (6.27e-2)" "unprognostic (2.73e-3)" "unprognostic (1.04e-1)" "unprognostic (6.90e-2)" "unprognostic (2.79e-3)" "unprognostic (1.95e-1)" "unprognostic (1.95e-2)" "unprognostic (3.67e-3)" "unprognostic (3.55e-1)" "unprognostic (3.31e-1)" "unprognostic (1.34e-2)" TERT "EST2, hEST2, TCS1, TP2, TRT" ENSG00000164362 "Telomerase reverse transcriptase" O14746 5 1253147-1295068 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" "DNA-binding, Nucleotidyltransferase, Ribonucleoprotein, RNA-directed DNA polymerase, Transferase" "Cancer-related genes, Disease variant, Dyskeratosis congenita" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 11.8;Early primary spermatocytes: 11.0;Enteric stem cells: 2.7;Enteric transient amplifying cells: 2.8;Goblet cells: 2.7;Paneth cells: 3.9;Plasma cells: 5.4;Respiratory ionocytes: 2.5;Undifferentiated spermatogonia: 9.6" "Cell type enhanced" "Detected in some" "medium spiny neuron: 3.9;miscellaneous: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 2.7" "Stomach - Mitotic cells (Stomach), Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA054641, HPA065897" Supported Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 35 Nucleoplasm "Nuclear speckles, Cytosol" "HPA054641: , HPA065897: " "unprognostic (4.06e-1)" "potential prognostic unfavorable (1.85e-5)" "unprognostic (2.47e-3)" TES "DKFZP586B2022, TESS-2, TESTIN" ENSG00000135269 "Testin LIM domain protein" Q9UGI8 7 116210506-116258783 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "seminal vesicle: 185.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 444.0;Early spermatids: 485.5;Endometrial glandular cells: 387.2;Endometrial luminal cells: 439.3;Endometrial secretory cells: 337.7" "Cell type enhanced" "Detected in many" "endothelial cell: 57.4;leukocyte: 127.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Smooth muscle cells, Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA015269, HPA018123" Approved Supported "Plasma membrane,Cell Junctions,Focal adhesion sites,Cytosol" NA NA 9600 "Cluster 42: Non-specific - Vesicular transport" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 39: Non-specific - Transcription" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 25 "Focal adhesion sites, Cytosol" "Plasma membrane, Cell Junctions" "HPA015269: , HPA018123: " "unprognostic (1.56e-1)" "unprognostic (6.17e-2)" "unprognostic (4.79e-3)" "unprognostic (7.14e-3)" "unprognostic (2.08e-2)" "unprognostic (4.62e-2)" "unprognostic (1.10e-1)" "unprognostic (2.84e-2)" "unprognostic (8.26e-3)" "unprognostic (1.24e-2)" "potential prognostic favorable (3.26e-5)" "unprognostic (1.12e-2)" "unprognostic (1.58e-2)" "potential prognostic unfavorable (7.61e-4)" "unprognostic (1.72e-2)" "unprognostic (4.14e-2)" "unprognostic (8.50e-3)" "unprognostic (3.62e-2)" "unprognostic (3.99e-2)" "unprognostic (1.30e-1)" "unprognostic (8.95e-2)" "potential prognostic unfavorable (5.99e-5)" "unprognostic (3.38e-2)" "unprognostic (1.02e-1)" "unprognostic (2.30e-2)" "unprognostic (1.08e-2)" "unprognostic (9.15e-3)" "unprognostic (5.28e-2)" "unprognostic (1.30e-1)" "unprognostic (1.89e-2)" "unprognostic (1.49e-1)" TESC "CHP3, FLJ20607, TSC" ENSG00000088992 Tescalcin Q96BS2 12 117038923-117099479 "Predicted intracellular proteins" "Differentiation, Protein transport, Transport" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 310.5" "Cell type enhanced" "Detected in many" "Cholangiocytes: 220.4;Conjunctival goblet cells: 232.0;Epididymal principal cells: 267.2;Foveolar cells: 279.2;Late spermatids: 561.8;Megakaryocytes: 228.7;Mucous neck cells: 200.6;Oocytes: 271.7;Pancreatic duct cells: 304.7;Parietal cells: 213.9;Salivary acinar cells: 449.4;Urothelial cells: 390.2" "Cell type enhanced" "Detected in many" "pericyte: 376.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 262.4" "Lineage enriched" "Detected in all" 5 "monocytes: 262.4" "Cancer enhanced" "Detected in many" "Bile duct cancer: 88.8;Gastric cancer: 89.6;Leukemia: 85.6" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Heart muscle - Cardiomyocytes, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA053200 Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 60: Stomach - Digestion" "Cluster 51: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 8 Nucleoplasm Cytosol "HPA053200: " "unprognostic (8.14e-2)" "unprognostic (3.52e-3)" "unprognostic (2.27e-2)" "unprognostic (2.64e-2)" "unprognostic (4.47e-3)" "unprognostic (1.06e-3)" "unprognostic (9.13e-2)" "unprognostic (3.46e-1)" "potential prognostic favorable (5.15e-4)" "unprognostic (7.22e-2)" "unprognostic (1.28e-2)" "potential prognostic favorable (2.69e-4)" "unprognostic (1.28e-2)" "unprognostic (7.47e-3)" "unprognostic (8.55e-2)" "unprognostic (1.56e-1)" "unprognostic (6.45e-2)" "unprognostic (3.58e-2)" "unprognostic (1.38e-1)" "unprognostic (4.71e-2)" "unprognostic (2.63e-2)" "unprognostic (6.29e-2)" "unprognostic (1.30e-1)" "unprognostic (3.35e-2)" "unprognostic (5.13e-3)" "unprognostic (1.67e-1)" "unprognostic (3.89e-1)" "unprognostic (1.61e-1)" "unprognostic (2.64e-1)" "unprognostic (7.04e-2)" "unprognostic (3.62e-2)" TESK1 ENSG00000107140 "Testis associated actin remodelling kinase 1" Q15569 9 35605262-35610041 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 44.1;Late spermatids: 46.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 7 "unprognostic (3.46e-2)" "unprognostic (2.05e-1)" "unprognostic (8.16e-2)" "unprognostic (2.09e-1)" "unprognostic (3.15e-1)" "unprognostic (3.72e-2)" "unprognostic (6.98e-2)" "unprognostic (7.88e-2)" "unprognostic (2.51e-1)" "unprognostic (9.12e-2)" "potential prognostic favorable (3.47e-5)" "unprognostic (1.02e-1)" "unprognostic (3.23e-1)" "unprognostic (4.56e-3)" "unprognostic (1.38e-1)" "unprognostic (5.90e-2)" "unprognostic (3.98e-3)" "unprognostic (1.93e-2)" "unprognostic (7.22e-2)" "unprognostic (6.74e-2)" "unprognostic (1.30e-3)" "unprognostic (1.16e-1)" "unprognostic (5.34e-2)" "unprognostic (7.66e-2)" "unprognostic (2.69e-3)" "unprognostic (7.78e-2)" "unprognostic (1.78e-1)" "unprognostic (2.81e-2)" "unprognostic (8.06e-2)" "unprognostic (6.84e-2)" "unprognostic (9.92e-2)" TESK2 ENSG00000070759 "Testis associated actin remodelling kinase 2" Q96S53 1 45343883-45491163 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 19.1;Loop of henle epithelial cells: 22.8;Papillary tip epithelial cells: 73.7;Podocytes: 11.6;Proximal tubule cells: 25.8;Renal collecting duct intercalated cells: 13.6;Renal collecting duct principal cells: 27.4;Renal connecting tubule cells: 22.4;Tuft cells: 11.5" "Cell type enhanced" "Detected in some" "astrocyte: 2.4;Bergmann glia: 2.1;oligodendrocyte: 2.9" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 20.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Prostate - Prostate glandular cells, Skin - Keratinocyte (other), Spleen - B-cells (Spleen), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027257, HPA063869" Uncertain Enhanced Nucleoplasm NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 105: Non-specific - Mixed function" 14 Nucleoplasm "HPA027257: , HPA063869: " "unprognostic (2.37e-1)" "unprognostic (1.51e-1)" "unprognostic (2.22e-1)" "unprognostic (3.46e-2)" "unprognostic (8.43e-2)" "unprognostic (1.77e-1)" "unprognostic (2.10e-1)" "unprognostic (1.04e-2)" "potential prognostic favorable (8.84e-4)" "potential prognostic favorable (4.26e-5)" "unprognostic (1.59e-3)" "unprognostic (1.79e-1)" "unprognostic (6.01e-3)" "unprognostic (3.28e-2)" "unprognostic (3.20e-3)" "unprognostic (5.82e-2)" "unprognostic (4.05e-2)" "unprognostic (5.99e-2)" "unprognostic (3.29e-1)" "unprognostic (2.57e-1)" "unprognostic (2.07e-1)" "unprognostic (3.77e-1)" "unprognostic (2.75e-1)" "unprognostic (5.52e-3)" "unprognostic (1.01e-1)" "unprognostic (2.34e-2)" "unprognostic (5.51e-2)" "unprognostic (8.64e-2)" "unprognostic (3.11e-2)" "unprognostic (1.56e-1)" TESMIN "CXCDC2, MTL5" ENSG00000132749 "Testis expressed metallothionein like protein" Q9Y4I5 11 68707440-68751520 "Predicted intracellular proteins" "Differentiation, Meiosis, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "testis: 49.1" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 131.9;Early spermatids: 106.2;Endometrial luminal cells: 48.1;Late primary spermatocytes: 247.0;Late spermatids: 215.1;Oocytes: 78.3" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 19.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Corticotropes, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA018539 Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 49: Hindbrain - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 1 Nucleoplasm "Vesicles, Cytosol" "HPA018539: " "potential prognostic unfavorable (7.91e-4)" "unprognostic (1.00e-1)" "unprognostic (6.04e-3)" "unprognostic (2.80e-1)" "potential prognostic favorable (5.97e-5)" "unprognostic (1.01e-1)" "unprognostic (2.86e-1)" "unprognostic (3.18e-3)" "unprognostic (1.50e-3)" "unprognostic (2.94e-2)" "unprognostic (6.67e-3)" "potential prognostic unfavorable (5.59e-6)" "unprognostic (6.65e-3)" "unprognostic (8.02e-3)" "unprognostic (5.18e-2)" "unprognostic (7.25e-2)" "unprognostic (3.08e-1)" "unprognostic (1.86e-1)" "unprognostic (1.30e-3)" "unprognostic (1.19e-1)" "unprognostic (3.22e-2)" "unprognostic (9.81e-2)" "unprognostic (4.43e-2)" "unprognostic (1.19e-1)" "unprognostic (1.68e-1)" "unprognostic (1.38e-1)" TESPA1 "ITPRID3, KIAA0748" ENSG00000135426 "Thymocyte expressed, positive selection associated 1" A2RU30 12 54948015-54984762 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 79.7;lymphoid tissue: 70.0" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 36.6;Hematopoietic stem cells: 246.0;Innate lymphoid cells: 91.5;Mast cells: 207.4;Megakaryocyte progenitors: 117.8;Megakaryocyte-Erythroid progenitors: 168.6;NK-cells: 41.3;T-cells: 85.0;Thymocytes: 75.4" "Cell type enhanced" "Detected in many" "hippocampal CA1-3: 116.6;upper-layer intratelencephalic: 190.2" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in all" 5 "basal ganglia: 60.2;cerebral cortex: 117.8;white matter: 72.7" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 9 "Leukemia: 43.8;lymphoma: 27.0" "Adipose visceral - T-cells, Adrenal gland - T-cells, Colon - Mast cells, Kidney - T-cells, Skeletal muscle - Fibroblasts, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA058823, HPA079222" Approved Supported Cytosol NA NA "Cluster 11: T-cells - Unknown function" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 53: Neurons - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 9: T-cells - Adaptive immunity: Regulation" Cytosol "HPA058823: , HPA079222: " "unprognostic (1.04e-2)" "potential prognostic favorable (3.07e-5)" "potential prognostic favorable (8.75e-6)" "unprognostic (1.79e-1)" "unprognostic (5.00e-2)" "unprognostic (6.65e-2)" "unprognostic (1.75e-1)" "potential prognostic favorable (2.69e-4)" "unprognostic (1.83e-1)" "unprognostic (8.41e-2)" "unprognostic (1.11e-1)" "unprognostic (3.61e-1)" "potential prognostic favorable (5.95e-5)" "unprognostic (3.77e-1)" "unprognostic (9.31e-2)" "unprognostic (2.02e-1)" "unprognostic (7.02e-3)" "unprognostic (2.03e-2)" "unprognostic (1.91e-2)" "unprognostic (4.92e-2)" "unprognostic (5.14e-3)" "unprognostic (2.30e-2)" "unprognostic (1.28e-1)" "unprognostic (6.33e-2)" "unprognostic (1.90e-1)" "unprognostic (3.45e-2)" TET1 "bA119F7.1, CXXC6, KIAA1676, LCX" ENSG00000138336 "Tet methylcytosine dioxygenase 1" Q8NFU7 10 68560337-68694487 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, Dioxygenase, DNA-binding, Oxidoreductase, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Adipocytes: 109.6;Bergmann glia: 127.6;Extravillous trophoblasts: 160.3;Pituitary stem cells: 107.3" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in single" 16 "Testicular Germ Cell Tumor (TCGA): 14.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 7.3" "Colon - Enteric glia cells, Testis - Peritubular cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019032 Supported "Nucleoplasm,Nuclear membrane" NA NA "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 34: Testis cancer - Unknown function" "Cluster 89: Adipocytes - Lipid metabolism" 5 Nucleoplasm "Nuclear membrane" "HPA019032: " "unprognostic (1.92e-1)" "unprognostic (1.22e-1)" "potential prognostic favorable (1.85e-4)" "potential prognostic favorable (2.00e-4)" "unprognostic (3.95e-2)" "unprognostic (1.42e-1)" "unprognostic (3.35e-2)" TET2 "FLJ20032, KIAA1546" ENSG00000168769 "Tet methylcytosine dioxygenase 2" Q6N021 4 105145875-105279816 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Chromatin regulator, Dioxygenase, DNA-binding, Oxidoreductase" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "cDC: 585.8;monocytes: 956.9;Neutrophil progenitors: 630.4;Neutrophils: 1878.4;Podocytes: 813.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 55.7" "Lineage enriched" "Detected in all" 4 "granulocytes: 55.7" "Low cancer specificity" "Detected in all" "Spleen - Neutrophils_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043135 Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 55: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 44 Nucleoplasm Cytosol "HPA043135: " "unprognostic (1.18e-2)" "unprognostic (9.89e-2)" "unprognostic (1.71e-1)" "unprognostic (7.18e-2)" "unprognostic (9.33e-2)" "unprognostic (2.00e-1)" "unprognostic (1.38e-1)" "unprognostic (4.66e-3)" "unprognostic (2.86e-2)" "unprognostic (1.82e-1)" "potential prognostic favorable (1.04e-4)" "unprognostic (1.45e-3)" "unprognostic (2.99e-2)" "unprognostic (6.15e-2)" "unprognostic (2.97e-2)" "unprognostic (1.35e-1)" "unprognostic (7.49e-2)" "unprognostic (2.62e-3)" "unprognostic (4.72e-2)" "unprognostic (2.55e-2)" "unprognostic (4.14e-1)" "unprognostic (1.10e-2)" "unprognostic (2.54e-2)" "unprognostic (4.71e-3)" "unprognostic (1.92e-2)" "unprognostic (6.77e-2)" "unprognostic (1.93e-1)" "unprognostic (1.18e-1)" "unprognostic (2.17e-2)" "unprognostic (4.04e-2)" TET3 "hCG_40738, MGC22014" ENSG00000187605 "Tet methylcytosine dioxygenase 3" O43151 2 73984910-74108176 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Chromatin regulator, Developmental protein, Dioxygenase, DNA-binding, Oxidoreductase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 18.6;skin 1: 14.7" "Cell type enhanced" "Detected in many" "Neutrophils: 616.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Stomach - Gastric mucous cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050845 Uncertain Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 49: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 3 Nucleoplasm "Vesicles, Cytosol" "HPA050845: " "unprognostic (1.48e-1)" "unprognostic (5.22e-2)" "unprognostic (5.06e-2)" "unprognostic (3.19e-3)" "unprognostic (9.04e-2)" "unprognostic (3.01e-1)" "unprognostic (8.93e-2)" "unprognostic (3.44e-3)" "unprognostic (1.42e-1)" "unprognostic (4.70e-2)" "unprognostic (2.37e-2)" "unprognostic (1.78e-1)" "unprognostic (1.60e-1)" "potential prognostic unfavorable (1.48e-4)" "unprognostic (3.57e-1)" "unprognostic (2.90e-2)" "unprognostic (6.59e-2)" "unprognostic (7.56e-2)" "potential prognostic favorable (7.84e-5)" "unprognostic (6.44e-2)" "unprognostic (3.16e-2)" "unprognostic (1.81e-2)" "unprognostic (2.29e-3)" "unprognostic (6.60e-2)" "unprognostic (5.19e-2)" "unprognostic (2.95e-2)" "unprognostic (1.09e-1)" "unprognostic (8.81e-2)" "unprognostic (3.25e-1)" "unprognostic (9.11e-2)" "unprognostic (2.21e-1)" TEX10 "bA208F1.2, FLJ20287, Ipi1" ENSG00000136891 "Testis expressed 10" Q9NXF1 9 100302077-100352942 "Essential proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 136.6;Epicardial cells: 195.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Pancreas - Endothelial cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045434 Approved Nucleoplasm,Mitochondria NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 39: Testis - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 57 Nucleoplasm Mitochondria "HPA045434: " "unprognostic (1.51e-3)" "unprognostic (7.68e-3)" "unprognostic (6.00e-2)" "unprognostic (1.93e-1)" "unprognostic (6.15e-2)" "unprognostic (2.04e-2)" "unprognostic (3.00e-2)" "potential prognostic favorable (1.88e-4)" "unprognostic (1.85e-2)" "unprognostic (3.73e-2)" "potential prognostic favorable (2.19e-6)" "unprognostic (1.84e-3)" "unprognostic (1.42e-1)" "validated prognostic unfavorable (3.38e-6)" "validated prognostic unfavorable (5.71e-4)" "potential prognostic unfavorable (6.31e-4)" "unprognostic (8.00e-3)" "unprognostic (4.04e-1)" "unprognostic (1.20e-1)" "unprognostic (2.39e-1)" "unprognostic (4.06e-2)" "unprognostic (7.28e-2)" "unprognostic (1.12e-1)" "unprognostic (4.42e-2)" "unprognostic (2.02e-3)" "unprognostic (7.97e-2)" "unprognostic (1.88e-2)" "unprognostic (3.46e-2)" "unprognostic (1.77e-1)" "unprognostic (1.44e-1)" "unprognostic (5.07e-2)" TEX101 "CT131, MGC4766, SGRG, SPATA44, TES101RP" ENSG00000131126 "Testis expressed 101" Q9BY14 19 43401496-43418597 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 73 "testis: 111.4" "Cell type enriched" "Detected in some" 13 "Early primary spermatocytes: 1013.1" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in many" 5 "cerebral cortex: 45.4" "Immune cell enriched" "Detected in single" 557 "basophil: 55.7" "Lineage enriched" "Detected in single" 557 "granulocytes: 55.7" "Not detected" "Not detected" "Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA041915, HPA042513" Enhanced "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 6: Testis - Spermatogenesis" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 3: Early primary spermatocytes - Early meiosis" 1 "HPA041915: , HPA042513: " "unprognostic (1.81e-1)" "unprognostic (1.37e-1)" "unprognostic (6.78e-1)" "unprognostic (1.86e-2)" "unprognostic (2.72e-2)" TEX11 "MZIP4, Spo22, TGC1, TSGA3, ZIP4" ENSG00000120498 "Testis expressed 11" Q8IYF3 X 70528940-70908711 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Meiosis "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "pancreas: 55.5" "Group enriched" "Detected in many" 4 "Choroid plexus epithelial cells: 45.8;Differentiating spermatogonia: 126.2;Early primary spermatocytes: 181.5;Late spermatids: 46.3;Pancreatic acinar cells: 47.0" "Cell type enriched" "Detected in many" 7 "choroid plexus epithelial cell: 33.4" "Cancer enhanced" "Detected in some" "Kidney Renal Clear Cell Carcinoma (TCGA): 4.2;Testicular Germ Cell Tumor (TCGA): 2.7" "Region enriched" "Detected in some" 8 "choroid plexus: 8.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 3.4;Gastric cancer: 1.6" "Pancreas - Exocrine glandular cells, Spleen - Fibroblasts_1, Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA002950 Approved NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 36: Choroid plexus - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 3: Early primary spermatocytes - Early meiosis" 40 "HPA002950: " "potential prognostic favorable (1.60e-5)" "unprognostic (2.48e-2)" "unprognostic (1.28e-1)" "unprognostic (1.05e-1)" "unprognostic (3.60e-3)" "unprognostic (4.91e-2)" "unprognostic (1.85e-1)" TEX12 ENSG00000150783 "Testis expressed 12" Q9BXU0 11 112167372-112172556 "Predicted intracellular proteins" Meiosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "retina: 8.0;testis: 19.3" "Cell type enriched" "Detected in single" 6 "Early primary spermatocytes: 4.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Spermatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038289, HPA038290" Enhanced Supported "Centrosome,Basal body" NA NA "Cluster 47: Testis - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 3: Early primary spermatocytes - Early meiosis" 30 "Centrosome, Basal body" "HPA038289: , HPA038290: " "unprognostic (2.58e-3)" TEX13A ENSG00000268629 "Testis expressed 13A" Q9BXU3 X 105218929-105220694 "Predicted intracellular proteins" "Transcription, Transcription regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 101 "testis: 10.0" "Cell type enhanced" "Detected in some" "Early spermatids: 87.4;Late primary spermatocytes: 50.8;Late spermatids: 226.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" HPA072257 Enhanced NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 12 "HPA072257: " TEX13B "TGC3B, TSGA5" ENSG00000170925 "Testis expressed 13B" Q9BXU2 X 107980864-107982370 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Spermatogonia" NA NA "Cluster 33: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 3 TEX13C ENSG00000282815 "TEX13 family member C" A0A0J9YWL9 X 125319871-125325216 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 16 "testis: 1.6" "Group enriched" "Detected in some" 5 "Differentiating spermatogonia: 4.9;Early primary spermatocytes: 10.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Skin Cutaneous Melanoma (TCGA): 1.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 14 "Gallbladder cancer: 20.5" "Testis - Spermatocytes" HPA050072 Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 3: Early primary spermatocytes - Early meiosis" "Plasma membrane" Nucleoplasm "HPA050072: " "unprognostic (3.16e-1)" TEX13D ENSG00000282419 "TEX13 family member D" A0A0J9YY54 X 124246249-124336863 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 17 "testis: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Spermatocytes" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 55: Lymphoma - Immune response" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" TEX14 CT113 ENSG00000121101 "Testis expressed 14, intercellular bridge forming factor" Q8IWB6 17 58556678-58692055 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "testis: 25.2" "Cell type enhanced" "Detected in many" "Breast lactating cells: 443.5;Breast myoepithelial cells: 502.0;cDC: 602.4;Hematopoietic stem cells: 754.5;Hofbauer cells: 729.8;Innate lymphoid cells: 533.2;Kupffer cells: 423.3;pDCs: 1116.3;Plasma cells: 1046.3" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 32.3;endothelial cell: 35.8" "Cancer enhanced" "Detected in single" "Breast Invasive Carcinoma (TCGA): 1.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 2.1;Uterine cancer: 2.1" "Prostate - Prostate glandular cells, Testis - Spermatocytes" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA030620, HPA077020" Enhanced Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 25: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 20: Non-specific - Transcription regulation" 5 Cytosol "Vesicles, Plasma membrane" "HPA030620: , HPA077020: " "unprognostic (1.91e-2)" "unprognostic (1.21e-1)" "unprognostic (7.67e-3)" TEX15 CT42 ENSG00000133863 "Testis expressed 15, meiosis and synapsis associated" Q9BXT5 8 30831544-30913008 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, DNA damage, DNA repair, Meiosis, RNA-mediated gene silencing, Spermatogenesis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "endometrium 1: 6.3;smooth muscle: 4.9;testis: 11.3" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 179.1;Early primary spermatocytes: 420.2;Early spermatids: 125.5;Ependymal cells: 88.7;Lactotrophs: 44.9;Late primary spermatocytes: 124.6;Late spermatids: 69.4;Undifferentiated spermatogonia: 141.8" "Cell type enhanced" "Detected in many" "ependymal cell: 85.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skin - Hair cortex cells, Skin - Inner root sheath cells, Testis - Spermatocytes" "Region enhanced" "Detected in single" "olfactory bulb: 2.2" "Low region specificity" "Detected in all" HPA036800 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 75: Ovary - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 3: Early primary spermatocytes - Early meiosis" 1 "Nucleoplasm, Cytosol" "HPA036800: " "unprognostic (7.57e-2)" TEX19 FLJ35767 ENSG00000182459 "Testis expressed 19" Q8NA77 17 82359247-82363775 "Predicted intracellular proteins" "Differentiation, Meiosis, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 216 "testis: 30.0" "Cell type enriched" "Detected in some" 16 "Early primary spermatocytes: 404.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "lymphoma: 18.9;Myeloma: 25.0" "Not detected" "Not detected" HPA054577 Enhanced NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 3: Early primary spermatocytes - Early meiosis" 6 "HPA054577: " "unprognostic (4.52e-1)" TEX2 "HT008, KIAA1738, TMEM96" ENSG00000136478 "Testis expressed 2" Q8IWB9 17 64147227-64263260 "Predicted intracellular proteins, Predicted membrane proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 227.0;Neutrophil progenitors: 254.7;pDCs: 194.8;Pituicytes/FSCs: 184.5;Retinal pigment epithelial cells: 456.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "plasmacytoid DC: 20.6" "Lineage enriched" "Detected in many" 6 "dendritic cells: 20.6" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Prostate - Smooth muscle cells, Spleen - Endothelial cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020648, HPA057116" Approved Approved Nucleoplasm NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 27: Breast cancer - Unknown function" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 21 Nucleoplasm "HPA020648: , HPA057116: " "unprognostic (3.59e-1)" "unprognostic (2.50e-2)" "unprognostic (8.72e-2)" "unprognostic (4.51e-2)" "unprognostic (3.51e-3)" "unprognostic (3.10e-3)" "unprognostic (2.61e-1)" "unprognostic (4.66e-2)" "unprognostic (1.18e-1)" "unprognostic (3.48e-3)" "potential prognostic favorable (8.94e-8)" "unprognostic (1.26e-2)" "unprognostic (1.64e-1)" "unprognostic (7.64e-2)" "unprognostic (4.04e-2)" "unprognostic (6.17e-2)" "unprognostic (1.85e-1)" "unprognostic (9.98e-2)" "unprognostic (1.96e-1)" "unprognostic (1.16e-1)" "unprognostic (4.37e-2)" "unprognostic (2.15e-1)" "unprognostic (4.77e-2)" "unprognostic (2.34e-1)" "unprognostic (2.22e-2)" "unprognostic (1.00e-1)" "unprognostic (2.94e-1)" "unprognostic (1.62e-1)" "unprognostic (1.70e-1)" "unprognostic (5.76e-2)" "unprognostic (1.86e-1)" TEX22 ENSG00000226174 "Testis expressed 22" C9J3V5 14 105398538-105450106 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "testis: 5.5" "Group enriched" "Detected in many" 18 "Early spermatids: 305.2;Late primary spermatocytes: 245.2;Late spermatids: 970.7" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA065576 Enhanced NA NA "Cluster 67: Testis - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" "HPA065576: " "unprognostic (2.45e-2)" TEX26 "C13orf26, MGC40178" ENSG00000175664 "Testis expressed 26" Q8N6G2 13 30932656-30975500 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "choroid plexus: 11.2;testis: 20.1" "Group enriched" "Detected in some" 8 "Early spermatids: 1081.0;Late spermatids: 2861.3" "Group enriched" "Detected in many" 4 "choroid plexus epithelial cell: 55.3;ependymal cell: 104.1" "Cancer enriched" "Detected in single" 6 "Glioblastoma Multiforme (TCGA): 3.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA079709 Approved "Golgi apparatus" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 72: Neuronal - Signal transduction" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" "Golgi apparatus" "HPA079709: " "unprognostic (2.01e-2)" "potential prognostic unfavorable (2.13e-4)" TEX261 "MGC32043, TEG-261" ENSG00000144043 "Testis expressed 261" Q6UWH6 2 70968325-70994873 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in some" 4 "Tuft cells: 11.5" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Adrenal cortex cells, Pituitary gland - Corticotropes, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016631 Approved Uncertain Nucleoplasm,Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 95: Tuft cells - Chemosensory signaling" Nucleoplasm Cytosol "HPA016631: " "unprognostic (6.87e-3)" "unprognostic (1.56e-2)" "unprognostic (6.31e-2)" "unprognostic (1.73e-2)" "unprognostic (1.48e-1)" "unprognostic (1.63e-1)" "unprognostic (1.61e-1)" "unprognostic (9.74e-3)" "unprognostic (7.01e-2)" "unprognostic (7.80e-2)" "potential prognostic favorable (7.13e-5)" "unprognostic (2.76e-2)" "unprognostic (9.82e-2)" "potential prognostic unfavorable (5.13e-6)" "unprognostic (2.46e-3)" "unprognostic (3.54e-1)" "unprognostic (1.97e-1)" "unprognostic (1.40e-1)" "unprognostic (1.02e-1)" "unprognostic (2.52e-3)" "unprognostic (3.67e-2)" "unprognostic (5.83e-2)" "unprognostic (3.61e-1)" "unprognostic (6.70e-2)" "unprognostic (2.03e-1)" "unprognostic (1.59e-1)" "unprognostic (1.45e-1)" "unprognostic (4.34e-2)" "unprognostic (2.09e-1)" "unprognostic (2.80e-1)" "unprognostic (2.13e-1)" TEX264 "FLJ13935, ZSIG11" ENSG00000164081 "Testis expressed 264, ER-phagy receptor" Q9Y6I9 3 51662693-51704323 "Plasma proteins, Predicted intracellular proteins" "Autophagy, DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 288.2;Late primary spermatocytes: 358.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Skin - Keratinocyte (granular), Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005002, HPA017739, HPA073223" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 27: Non-specific - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 3: Early primary spermatocytes - Early meiosis" 48 "Endoplasmic reticulum" "CAB005002: , HPA017739: , HPA073223: " "unprognostic (2.54e-2)" "unprognostic (2.98e-2)" "unprognostic (1.70e-1)" "unprognostic (3.08e-1)" "unprognostic (3.67e-2)" "unprognostic (2.85e-2)" "unprognostic (3.85e-2)" "unprognostic (3.60e-2)" "unprognostic (1.40e-1)" "unprognostic (5.73e-2)" "unprognostic (9.63e-3)" "unprognostic (1.02e-1)" "potential prognostic favorable (2.39e-4)" "unprognostic (7.83e-2)" "unprognostic (9.33e-3)" "unprognostic (1.34e-1)" "unprognostic (1.35e-2)" "unprognostic (1.23e-1)" "unprognostic (5.71e-2)" "unprognostic (1.22e-1)" "unprognostic (1.45e-1)" "unprognostic (2.11e-2)" "unprognostic (4.24e-2)" "unprognostic (7.18e-2)" "unprognostic (7.85e-2)" "unprognostic (7.77e-2)" "unprognostic (2.11e-1)" "unprognostic (5.30e-3)" "unprognostic (1.71e-1)" "unprognostic (1.61e-1)" "unprognostic (1.38e-2)" TEX28 "CXorf2, fTEX" ENSG00000278057 "Testis expressed 28" O15482 X 154271265-154295853 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 48 "testis: 8.6" "Cell type enhanced" "Detected in single" "Neutrophils: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 47: Leukemia - Hemostasis" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 13 TEX29 "bA474D23.1, C13orf16, MGC35169" ENSG00000153495 "Testis expressed 29" Q8N6K0 13 111316184-111344249 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "testis: 48.8" "Cell type enriched" "Detected in many" 4 "Early spermatids: 1108.0" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lymphoma: 1.0" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 67: Testis - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 26 "potential prognostic favorable (1.28e-4)" "unprognostic (4.90e-2)" TEX30 C13orf27 ENSG00000151287 "Testis expressed 30" Q5JUR7 13 102765888-102773811 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "epididymis: 67.3;liver: 37.4;testis: 114.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 153.7;Differentiating spermatogonia: 177.4;Early primary spermatocytes: 928.9;Early spermatids: 348.4;Epididymal principal cells: 194.3;Extravillous trophoblasts: 157.9;Late primary spermatocytes: 979.3;Oocytes: 437.5;Syncytiotrophoblasts: 176.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "basophil: 365.7" "Lineage enriched" "Detected in all" 13 "granulocytes: 365.7" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053545 Enhanced NA NA "Cluster 41: Basophils - Unknown function" "Cluster 22: Epididymis - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" "HPA053545: " "unprognostic (1.82e-1)" "unprognostic (1.09e-1)" "unprognostic (1.39e-2)" "unprognostic (1.44e-1)" "unprognostic (9.11e-2)" "unprognostic (9.24e-2)" "potential prognostic favorable (3.36e-4)" "unprognostic (1.20e-2)" "unprognostic (3.61e-3)" "unprognostic (3.90e-2)" "unprognostic (1.06e-1)" "unprognostic (9.54e-3)" "unprognostic (1.77e-1)" "unprognostic (2.48e-3)" "unprognostic (2.68e-3)" "unprognostic (2.36e-2)" "unprognostic (1.84e-1)" "unprognostic (8.01e-2)" "unprognostic (1.10e-1)" "unprognostic (2.18e-1)" "unprognostic (1.14e-3)" "potential prognostic unfavorable (1.09e-4)" "unprognostic (3.49e-2)" "unprognostic (1.81e-1)" "unprognostic (1.19e-2)" "unprognostic (3.08e-1)" "unprognostic (1.08e-2)" "unprognostic (1.64e-1)" "unprognostic (5.74e-2)" TEX33 "C22orf33, EAN57, MGC35206" ENSG00000185264 "Testis expressed 33" O43247 22 36991120-37007851 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 616 "testis: 79.6" "Group enriched" "Detected in some" 149 "Early spermatids: 1058.5;Late primary spermatocytes: 381.0;Late spermatids: 293.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA005998 Enhanced NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" "HPA005998: " TEX35 "C1orf49, DKFZP564J047, TSC24" ENSG00000240021 "Testis expressed 35" Q5T0J7 1 178513109-178548602 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 62 "testis: 112.2" "Group enriched" "Detected in some" 8 "Early spermatids: 1551.2;Late spermatids: 3259.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Stomach Adenocarcinoma (TCGA): 1.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Stomach - Gastric mucous cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA039190 Approved NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 9: Non-specific - Receptor signaling" "Cluster 56: Non-specific - Sensory perception" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" "HPA039190: " "unprognostic (7.41e-2)" "unprognostic (8.44e-2)" "unprognostic (1.15e-2)" "unprognostic (4.60e-3)" "unprognostic (1.32e-1)" TEX36 "bA383C5.1, C10orf122" ENSG00000175018 "Testis expressed 36" Q5VZQ5 10 125576522-125683163 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 54 "testis: 25.0" "Group enriched" "Detected in some" 96 "Early spermatids: 429.0;Late primary spermatocytes: 175.3;Late spermatids: 631.4" "Cell type enhanced" "Detected in single" "endothelial cell: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in single" 15 "cerebellum: 2.3" "Low region specificity" "Detected in some" HPA077263 Approved Vesicles,Cytosol NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" Vesicles Cytosol "HPA077263: " TEX37 "C2orf51, FLJ25369, TSC21" ENSG00000172073 "Testis expressed 37" Q96LM6 2 88524649-88529585 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 763 "testis: 81.4" "Group enriched" "Detected in some" 76 "Early spermatids: 1114.1;Late spermatids: 4156.6" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 16 "Testicular Germ Cell Tumor (TCGA): 3.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "testis cancer: 1.4" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA043987, HPA070239" Enhanced Supported "Cytosol,Connecting piece,Mid piece,Principal piece,End piece" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 34: Testis cancer - Unknown function" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 34 "Cytosol, Connecting piece, Mid piece, Principal piece, End piece" "HPA043987: , HPA070239: " "unprognostic (1.28e-1)" TEX38 "ATPAF1-AS1, C1orf223, LOC374973, THEG4" ENSG00000186118 "Testis expressed 38" Q6PEX7 1 46668855-46673594 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 428 "testis: 377.3" "Group enriched" "Detected in some" 4 "Early spermatids: 2549.3;Late spermatids: 8497.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 1.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA073711 Approved Vesicles NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 15: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" Vesicles "HPA073711: " "unprognostic (1.76e-1)" "unprognostic (3.15e-1)" TEX43 "C5orf48, FLJ27505, MGC163367, MGC163369, Tseg7" ENSG00000196900 "Testis expressed 43" Q6ZNM6 5 126631705-126636284 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 36 "testis: 21.4" "Cell type enhanced" "Detected in some" "Early spermatids: 655.9;Late primary spermatocytes: 104.0;Late spermatids: 169.9" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Rectum Adenocarcinoma (TCGA): 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA043794 Approved "Mid piece" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 5 "Mid piece" "HPA043794: " "unprognostic (1.01e-2)" "unprognostic (4.34e-2)" "unprognostic (9.29e-3)" TEX44 "C2orf57, MGC35154" ENSG00000177673 "Testis expressed 44" Q53QW1 2 231592864-231594276 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1008 "testis: 146.5" "Cell type enriched" "Detected in some" 5 "Late spermatids: 5983.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "HPA049917, HPA056433" Enhanced NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 11 "HPA049917: , HPA056433: " TEX45 "C19orf45, FLJ35784" ENSG00000198723 "Testis expressed 45" Q8NA69 19 7492976-7508450 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "testis: 19.4" "Group enriched" "Detected in some" 6 "Early spermatids: 255.9;Late spermatids: 643.5" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA066278 Approved "Mid piece,Principal piece,End piece" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 11: White matter - Signal transduction" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 4 "Mid piece, Principal piece, End piece" "HPA066278: " "unprognostic (2.28e-1)" "unprognostic (7.46e-2)" "unprognostic (3.21e-1)" "unprognostic (1.58e-1)" "unprognostic (1.60e-1)" TEX46 C1orf234 ENSG00000227868 "Testis expressed 46" H3BTG2 1 23010834-23019100 "Predicted intracellular proteins" Fertilization "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 83 "testis: 58.5" "Cell type enriched" "Detected in some" 4 "Late spermatids: 3550.6" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 11: White matter - Signal transduction" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" TEX47 "C7orf62, DYBLUF, MGC26647" ENSG00000164645 "Testis expressed 47" Q8TBZ9 7 88794106-88795737 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 159 "testis: 27.0" "Group enriched" "Detected in some" 51 "Early spermatids: 163.0;Late primary spermatocytes: 177.0;Late spermatids: 106.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Region enhanced" "Detected in many" "olfactory bulb: 8.5" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 1: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" TEX48 ENSG00000230601 "Testis expressed 48" A0A1B0GUV7 9 114666434-114682192 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 127 "testis: 24.7" "Group enriched" "Detected in some" 4 "Early spermatids: 344.5;Late spermatids: 1354.1" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Adrenocortical cancer: 1.0" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 53: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 2 TEX49 LINC00935 ENSG00000257987 "Testis expressed 49" A0A1B0GTD5 12 48727435-48765790 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "testis: 19.6" "Group enriched" "Detected in some" 4 "Early spermatids: 391.6;Late spermatids: 336.1" "Low cell type specificity" "Detected in single" "Cancer enriched" "Detected in single" 4 "Testicular Germ Cell Tumor (TCGA): 1.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" "unprognostic (1.74e-1)" TEX50 ENSG00000232113 "Testis expressed 50" A0A1B0GTY4 1 173635338-173637130 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 200 "testis: 20.0" "Cell type enhanced" "Detected in some" "Early spermatids: 259.6;Late primary spermatocytes: 169.3;Late spermatids: 59.8" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 17: Choroid plexus - Cilium" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" TEX51 ENSG00000237524 "Testis expressed 51" A0A1B0GUA7 2 126898864-126902097 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 181 "testis: 59.8" "Group enriched" "Detected in some" 162 "Early spermatids: 494.4;Late primary spermatocytes: 319.3;Late spermatids: 294.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" TEX52 ENSG00000283297 "Testis expressed 52" A6NCN8 12 2849046-2857039 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 7.9" "Group enriched" "Detected in some" 18 "Early spermatids: 192.8;Late spermatids: 269.4" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 3.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "NK-cell: 1.1" "Lineage enriched" "Detected in single" 7 "NK-cells: 1.1" "Low cancer specificity" "Detected in many" "Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043581 Approved Nucleoplasm,Cytosol NA NA "Cluster 47: Testis - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 56: Non-specific - Sensory perception" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" Nucleoplasm Cytosol "HPA043581: " "unprognostic (1.72e-1)" "unprognostic (1.29e-1)" "unprognostic (1.24e-1)" TEX53 ENSG00000230054 "Testis expressed 53" A0A1B0GU33 9 114656304-114662374 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 166 "testis: 66.0" "Cell type enriched" "Detected in some" 5 "Late spermatids: 4475.2" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 53: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" TEX54 ENSG00000283268 "Testis expressed 54" A0A1B0GVG6 11 62832321-62832841 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 42 "testis: 73.5" "Cell type enhanced" "Detected in some" "Adipocytes: 15.3;Cardiomyocytes: 6.0;Early spermatids: 54.1;Epicardial cells: 18.2;Late primary spermatocytes: 10.5;Late spermatids: 4.7" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 6 "neutrophil: 139.5" "Lineage enriched" "Detected in all" 17 "granulocytes: 139.5" "Low cancer specificity" "Detected in some" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 79: Testis - Spermatogenesis" "Cluster 25: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 89: Adipocytes - Lipid metabolism" "unprognostic (7.77e-2)" "unprognostic (3.66e-2)" "unprognostic (1.23e-1)" TEX55 "C3orf30, FLJ32859, TSCPA" ENSG00000163424 "Testis expressed 55" Q96M34 3 119146151-119160042 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 290 "testis: 50.2" "Group enriched" "Detected in some" 4 "Early spermatids: 670.2;Late spermatids: 518.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA062468 Enhanced Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 1 Nucleoplasm "Vesicles, Plasma membrane, Cytosol" "HPA062468: " TEX9 ENSG00000151575 "Testis expressed 9" Q8N6V9 15 56243971-56445997 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 256.1;Endometrial ciliated cells: 218.5;Ependymal cells: 465.1;Epididymal efferent duct ciliated cells: 197.7;Fallopian tube ciliated cells: 287.6;Lactotrophs: 193.8;Respiratory ciliated cells: 344.8" "Cell type enhanced" "Detected in all" "ependymal cell: 500.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory B-cell: 10.0;naive B-cell: 8.5" "Lineage enriched" "Detected in many" 5 "B-cells: 10.0" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Skeletal muscle - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039415, HPA042036" Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Primary cilium,Centrosome,Basal body,Cytosol" NA NA "Cluster 32: Basophils - Transcription" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" 14 "Primary cilium, Centrosome, Cytosol" "Nucleoplasm, Nucleoli fibrillar center, Vesicles, Basal body" "HPA039415: , HPA042036: " "unprognostic (2.81e-1)" "unprognostic (1.08e-1)" "unprognostic (1.18e-1)" "unprognostic (1.02e-1)" "unprognostic (3.24e-1)" "unprognostic (5.00e-2)" "unprognostic (2.21e-1)" "unprognostic (2.18e-1)" "unprognostic (9.42e-2)" "unprognostic (1.21e-3)" "potential prognostic favorable (1.05e-6)" "unprognostic (2.61e-3)" "unprognostic (4.91e-2)" "unprognostic (4.28e-1)" "unprognostic (5.79e-2)" "unprognostic (6.87e-2)" "unprognostic (2.14e-1)" "unprognostic (9.62e-2)" "unprognostic (1.11e-1)" "unprognostic (4.40e-2)" "unprognostic (2.41e-2)" "unprognostic (1.69e-1)" "unprognostic (4.30e-2)" "unprognostic (1.22e-2)" "unprognostic (4.02e-1)" "unprognostic (2.58e-2)" "unprognostic (2.28e-1)" "unprognostic (6.78e-2)" "unprognostic (3.38e-2)" "unprognostic (1.66e-1)" TF "PRO1557, PRO2086" ENSG00000091513 Transferrin P02787 3 133746040-133796641 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Ion transport, Iron transport, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "liver: 7020.0;retina: 2256.7" "Group enriched" "Detected in many" 7 "Hepatocytes: 8185.4;Müller glia: 11977.3" "Group enriched" "Detected in all" 11 "committed oligodendrocyte precursor: 554.6;oligodendrocyte: 1970.0" "Cancer enriched" "Detected in many" 26 "Liver Hepatocellular Carcinoma (TCGA): 1360.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "liver cancer: 221.9" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Colon - Enteric glia cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary gland ductal cells, Prostate - Prostate basal glandular cells, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001527, HPA005692, CAB009538" Enhanced "Secreted to blood" Transport NA NA 19800000000000 250000000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 30: White matter - Myelination" "Cluster 18: Liver cancer - Metabolism" "Cluster 11: Muller glia cells - Retinal homeostasis" 47 "CAB009538: , HPA001527: , HPA005692: " "unprognostic (7.07e-2)" "unprognostic (2.66e-2)" "unprognostic (5.06e-2)" "unprognostic (4.11e-2)" "unprognostic (1.22e-1)" "unprognostic (3.68e-2)" "unprognostic (1.89e-2)" "unprognostic (1.95e-2)" "potential prognostic unfavorable (2.44e-4)" "unprognostic (2.42e-3)" "unprognostic (2.43e-1)" "unprognostic (1.03e-1)" "unprognostic (1.78e-1)" "unprognostic (7.60e-2)" "unprognostic (1.44e-1)" "unprognostic (1.21e-1)" "unprognostic (5.67e-2)" "unprognostic (2.62e-1)" "unprognostic (2.82e-1)" "unprognostic (1.37e-3)" "unprognostic (3.62e-1)" "unprognostic (4.59e-3)" "unprognostic (4.23e-2)" "unprognostic (2.46e-3)" "unprognostic (2.63e-2)" "unprognostic (2.84e-1)" TFAM "TCF6, TCF6L2" ENSG00000108064 "Transcription factor A, mitochondrial" Q00059 10 58385345-58399220 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 7 "Early spermatids: 785.5;Late spermatids: 1338.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040648, HPA063684" Supported Enhanced Mitochondria NA NA "Cluster 24: Non-specific - Transcription" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 50 Mitochondria "HPA040648: , HPA063684: " "unprognostic (8.64e-2)" "unprognostic (4.27e-2)" "unprognostic (1.75e-3)" "unprognostic (9.80e-2)" "unprognostic (1.12e-1)" "potential prognostic favorable (7.17e-4)" "unprognostic (3.72e-2)" "potential prognostic favorable (6.12e-6)" "unprognostic (5.28e-2)" "unprognostic (2.59e-3)" "potential prognostic favorable (7.90e-8)" "unprognostic (1.15e-1)" "unprognostic (1.31e-2)" "unprognostic (2.46e-3)" "unprognostic (9.45e-3)" "unprognostic (3.03e-3)" "unprognostic (5.55e-3)" "unprognostic (2.98e-1)" "unprognostic (5.08e-2)" "unprognostic (1.86e-1)" "unprognostic (4.46e-2)" "unprognostic (6.86e-3)" "unprognostic (8.02e-2)" "unprognostic (1.35e-2)" "unprognostic (2.52e-2)" "unprognostic (9.98e-2)" "unprognostic (2.15e-2)" "unprognostic (2.89e-1)" "unprognostic (2.09e-1)" "unprognostic (4.15e-2)" "unprognostic (5.42e-2)" TFAP2A "AP-2, AP-2alpha, AP2TF, TFAP2" ENSG00000137203 "Transcription factor AP-2 alpha" P05549 6 10393186-10419659 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 30.8;skin 1: 63.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 133.4;Breast hormone-responsive cells: 158.2;Cytotrophoblasts: 344.5;Extravillous trophoblasts: 368.5;Melanocytes: 387.8;Migrating cytotrophoblasts: 324.0;Retinal amacrine cells: 175.7;Syncytiotrophoblasts: 884.2" "Cell type enriched" "Detected in some" 6 "cerebellar inhibitory: 69.0" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 159.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Colon - Enteric glia cells, Lung - Respiratory ciliated cells, Skin - Keratinocyte (other), Testis - Spermatogonia" "Group enriched" "Detected in some" 4 "cerebellum: 3.9;pons and medulla: 1.0" "Low region specificity" "Detected in many" "CAB000326, HPA056871" Enhanced Enhanced Nucleoplasm NA NA "Cluster 37: Skin - Keratinization" "Cluster 25: Non-specific - Transcription" "Cluster 69: Skin cancer - ECM organization" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 40 Nucleoplasm "CAB000326: , HPA056871: " "unprognostic (8.18e-3)" "unprognostic (7.69e-2)" "unprognostic (4.31e-2)" "unprognostic (1.16e-2)" "unprognostic (5.60e-2)" "unprognostic (2.05e-1)" "unprognostic (3.86e-2)" "unprognostic (1.96e-1)" "unprognostic (2.22e-1)" "unprognostic (2.03e-2)" "validated prognostic unfavorable (1.37e-7)" "validated prognostic unfavorable (4.49e-5)" "potential prognostic unfavorable (3.51e-5)" "potential prognostic unfavorable (9.37e-7)" "unprognostic (4.03e-2)" "potential prognostic unfavorable (2.33e-6)" "unprognostic (7.41e-3)" "unprognostic (7.42e-2)" "unprognostic (2.34e-1)" "unprognostic (1.82e-2)" "unprognostic (1.14e-1)" "unprognostic (4.14e-3)" "unprognostic (1.25e-2)" "unprognostic (1.43e-1)" "unprognostic (9.73e-2)" "unprognostic (4.87e-2)" "unprognostic (1.26e-1)" "unprognostic (1.68e-2)" "unprognostic (2.07e-1)" "unprognostic (9.86e-2)" TFAP2B "AP-2beta, AP2-B" ENSG00000008196 "Transcription factor AP-2 beta" Q92481 6 50818723-50847619 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 31.4;retina: 13.7" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 117.0;Breast hormone-responsive cells: 96.5;Distal convoluted tubule cells: 78.7;Epididymal principal cells: 147.4;Lacrimal acinar cells: 63.4;Loop of henle epithelial cells: 107.6;Melanocytes: 231.0;Retinal amacrine cells: 594.4;Retinal horizontal cells: 376.6" "Cell type enriched" "Detected in some" 21 "cerebellar inhibitory: 230.9" "Cancer enriched" "Detected in some" 11 "Breast Invasive Carcinoma (TCGA): 22.7" "Group enriched" "Detected in many" 6 "cerebellum: 7.2;medulla oblongata: 8.2;midbrain: 19.8;pons: 21.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "Bone cancer: 22.5;breast cancer: 22.4;Neuroblastoma: 51.4" "Adrenal gland - Adrenal medulla cells, Breast - Breast glandular cells, Breast - Breast glandular cells, Kidney - Ascending Loop of Henle cells, Pituitary gland - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Region enhanced" "Detected in many" "cerebellum: 10.0" "Region enhanced" "Detected in many" "cerebellum: 13.8" "HPA034683, HPA062942" Enhanced Approved Nucleoplasm NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 4 Nucleoplasm "HPA034683: , HPA062942: " "unprognostic (2.79e-1)" "unprognostic (5.34e-2)" "unprognostic (2.53e-2)" "unprognostic (2.41e-1)" "unprognostic (3.04e-2)" "unprognostic (2.76e-1)" "unprognostic (2.62e-1)" TFAP2C "AP2-GAMMA, ERF1, hAP-2g, TFAP2G" ENSG00000087510 "Transcription factor AP-2 gamma" Q92754 20 56629306-56639283 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 27.5;skin 1: 50.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 127.9;Breast myoepithelial cells: 149.0;Breast secretory cells: 106.3;Cytotrophoblasts: 116.2;Esophageal apical cells: 72.7;Extravillous trophoblasts: 105.5;Migrating cytotrophoblasts: 124.6;Salivary myoepithelial cells: 83.3;Suprabasal keratinocytes: 116.8;Syncytiotrophoblasts: 129.3;Tuft cells: 80.7" "Group enriched" "Detected in some" 4 "astrocyte: 3.4;endothelial cell: 6.0;fibroblast: 12.7" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 83.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 77.7" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other), Testis - Spermatogonia" "Region enriched" "Detected in single" 13 "olfactory bulb: 2.4" "Region enhanced" "Detected in single" "olfactory bulb: 2.5" "CAB016061, CAB016079, HPA055179, HPA057076" Enhanced Supported Nucleoplasm Yes NA "Cluster 58: Skin - Keratinization" "Cluster 51: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 9 Nucleoplasm "CAB016061: , CAB016079: , HPA055179: , HPA057076: " "unprognostic (2.68e-1)" "unprognostic (5.45e-2)" "unprognostic (2.23e-1)" "unprognostic (3.94e-2)" "unprognostic (7.30e-2)" "unprognostic (9.58e-2)" "unprognostic (8.69e-3)" "unprognostic (4.61e-2)" "unprognostic (8.74e-2)" "unprognostic (9.65e-2)" "unprognostic (1.54e-1)" "unprognostic (4.23e-2)" "unprognostic (8.32e-3)" "unprognostic (1.98e-2)" "unprognostic (1.17e-1)" "unprognostic (2.24e-1)" "unprognostic (2.12e-3)" "unprognostic (4.91e-2)" "unprognostic (1.39e-1)" "unprognostic (4.33e-1)" "unprognostic (6.62e-2)" "unprognostic (1.08e-1)" "unprognostic (3.96e-1)" "unprognostic (5.24e-1)" "unprognostic (1.25e-1)" "unprognostic (9.18e-2)" TFAP2D "AP-2delta, TFAP2BL1" ENSG00000008197 "Transcription factor AP-2 delta" Q7Z6R9 6 50713526-50773033 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Brain excitatory neurons: 7.6;Oocytes: 4.6;Retinal amacrine cells: 5.6;Retinal ganglion cells: 15.5" "Cell type enhanced" "Detected in some" "amygdala excitatory: 15.1;deep-layer intratelencephalic: 5.8;splatter: 5.0" "Not detected" "Not detected" "Region enriched" "Detected in some" 5 "midbrain: 13.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in many" 4 "midbrain: 11.8" "Region enriched" "Detected in some" 5 "midbrain: 11.6" HPA048962 Uncertain "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 19: Astrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 109: Neurons - Neuronal signaling" 49 Nucleoplasm "Golgi apparatus, Vesicles" "HPA048962: " "unprognostic (7.02e-2)" TFAP2E "AP-2epsilon, AP2E" ENSG00000116819 "Transcription factor AP-2 epsilon" Q6VUC0 1 35573314-35595328 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 9.7;retina: 3.2" "Cell type enhanced" "Detected in many" "Retinal amacrine cells: 70.3;Retinal bipolar cells: 73.2;Retinal ganglion cells: 27.0;Rod photoreceptor cells: 32.8" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Adrenocortical cancer: 2.8" "Skin - Keratinocyte (other), Thyroid gland - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 32: Basophils - Transcription" "Cluster 71: Cerebellum - Nervous system development" "Cluster 15: Non-specific - Transcription" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "unprognostic (2.33e-1)" "potential prognostic favorable (5.98e-5)" TFAP4 "AP-4, bHLHc41" ENSG00000090447 "Transcription factor AP-4" Q01664 16 4257186-4273075 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Enterocytes: 34.9;Gastric chief cells: 28.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001912 Supported Approved Nucleoplasm,Mitochondria NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 36 "Nucleoplasm, Mitochondria" "HPA001912: " "unprognostic (2.32e-1)" "unprognostic (1.22e-1)" "unprognostic (5.49e-2)" "unprognostic (1.27e-2)" "unprognostic (1.17e-1)" "unprognostic (4.98e-2)" "unprognostic (9.17e-2)" "potential prognostic favorable (6.13e-4)" "unprognostic (1.18e-2)" "unprognostic (3.19e-2)" "unprognostic (9.35e-2)" "unprognostic (6.07e-2)" "unprognostic (1.18e-2)" "validated prognostic unfavorable (1.10e-4)" "validated prognostic unfavorable (9.78e-4)" "unprognostic (2.49e-1)" "unprognostic (4.94e-2)" "unprognostic (5.84e-2)" "unprognostic (4.04e-3)" "unprognostic (1.16e-1)" "unprognostic (1.45e-1)" "unprognostic (1.31e-2)" "unprognostic (5.94e-2)" "unprognostic (6.70e-3)" "unprognostic (3.12e-2)" "unprognostic (2.80e-2)" "unprognostic (7.71e-2)" "unprognostic (1.53e-1)" "unprognostic (1.16e-1)" "unprognostic (7.43e-2)" "unprognostic (1.89e-1)" TFB1M "CGI-75, mtTFB" ENSG00000029639 "Transcription factor B1, mitochondrial" Q8WVM0 6 155256134-155314493 "Disease related genes, Predicted intracellular proteins" "rRNA processing, Transcription, Transcription regulation" "DNA-binding, Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 235.5;Late primary spermatocytes: 206.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029428 Approved NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 53: Neurons - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 9 "HPA029428: " "unprognostic (3.22e-1)" "potential prognostic unfavorable (1.97e-4)" "unprognostic (5.15e-3)" "unprognostic (1.78e-1)" "unprognostic (8.56e-2)" "unprognostic (3.27e-1)" "unprognostic (5.61e-2)" "unprognostic (1.31e-2)" "unprognostic (1.42e-1)" "unprognostic (1.39e-1)" "unprognostic (4.05e-3)" "unprognostic (2.72e-1)" "unprognostic (2.17e-1)" "unprognostic (1.88e-2)" "unprognostic (3.70e-2)" "unprognostic (1.61e-2)" "unprognostic (2.19e-1)" "unprognostic (2.02e-1)" "unprognostic (1.38e-2)" "unprognostic (1.28e-2)" "unprognostic (8.65e-2)" "unprognostic (1.49e-1)" "unprognostic (2.45e-2)" "unprognostic (1.26e-1)" "unprognostic (6.52e-3)" "unprognostic (2.33e-1)" "unprognostic (2.21e-1)" "unprognostic (1.21e-1)" "unprognostic (3.55e-1)" "unprognostic (2.42e-1)" "unprognostic (1.90e-1)" TFB2M "FLJ22661, FLJ23182, Hkp1" ENSG00000162851 "Transcription factor B2, mitochondrial" Q9H5Q4 1 246540561-246566261 "Essential proteins, Predicted intracellular proteins" "rRNA processing, Transcription, Transcription regulation" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 82.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028482, HPA028554, HPA030265" Approved Enhanced Mitochondria NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 31: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 17 Mitochondria "HPA028482: , HPA028554: , HPA030265: " "unprognostic (2.83e-1)" "unprognostic (6.64e-3)" "unprognostic (2.02e-1)" "unprognostic (6.44e-2)" "unprognostic (2.24e-2)" "unprognostic (2.41e-2)" "unprognostic (1.25e-1)" "unprognostic (2.68e-1)" "unprognostic (2.55e-1)" "unprognostic (1.78e-2)" "potential prognostic favorable (1.06e-4)" "unprognostic (4.00e-2)" "unprognostic (7.35e-3)" "unprognostic (1.32e-2)" "unprognostic (2.47e-2)" "unprognostic (1.02e-1)" "unprognostic (6.07e-3)" "unprognostic (4.93e-2)" "unprognostic (6.52e-2)" "unprognostic (1.95e-2)" "unprognostic (2.12e-1)" "unprognostic (2.00e-2)" "unprognostic (2.00e-1)" "unprognostic (2.86e-2)" "unprognostic (5.91e-3)" "unprognostic (2.69e-1)" "unprognostic (1.40e-1)" "unprognostic (1.23e-1)" "unprognostic (1.07e-1)" "unprognostic (7.05e-2)" "unprognostic (9.14e-2)" TFCP2 "CP2, LBP-1C, LSF, TFCP2C" ENSG00000135457 "Transcription factor CP2" Q12800 12 51093656-51173135 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070247 Supported Nucleoplasm,Cytosol NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 69 Nucleoplasm Cytosol "HPA070247: " "unprognostic (2.03e-1)" "unprognostic (3.06e-1)" "unprognostic (4.41e-1)" "unprognostic (1.15e-2)" "unprognostic (2.21e-1)" "unprognostic (2.28e-2)" "unprognostic (5.74e-2)" "unprognostic (1.85e-1)" "unprognostic (1.19e-1)" "unprognostic (5.56e-2)" "potential prognostic favorable (4.09e-5)" "unprognostic (2.17e-2)" "unprognostic (5.09e-2)" "potential prognostic unfavorable (4.83e-4)" "unprognostic (2.13e-1)" "unprognostic (2.18e-2)" "unprognostic (1.37e-1)" "unprognostic (6.87e-2)" "unprognostic (2.82e-1)" "unprognostic (2.03e-1)" "unprognostic (2.58e-1)" "unprognostic (1.27e-1)" "unprognostic (9.80e-2)" "unprognostic (9.78e-2)" "unprognostic (3.38e-1)" "unprognostic (1.78e-1)" "unprognostic (6.93e-2)" "unprognostic (4.72e-1)" "unprognostic (3.98e-1)" "unprognostic (5.06e-2)" "unprognostic (8.08e-2)" TFCP2L1 "CRTR1, LBP-9" ENSG00000115112 "Transcription factor CP2 like 1" Q9NZI6 2 121216587-121285202 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 46.2;salivary gland: 92.0" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 568.5;Conjunctival goblet cells: 1196.1;Distal convoluted tubule cells: 669.9;Lacrimal acinar cells: 1463.8;Loop of henle epithelial cells: 585.3;Renal collecting duct intercalated cells: 1735.2;Renal connecting tubule cells: 629.5;Respiratory ionocytes: 1066.8;Salivary basal cells: 1409.5;Salivary duct cells: 2546.6;Salivary ionocytes: 1876.4;Submucosal glandular cells: 720.9" "Cell type enriched" "Detected in some" 6 "choroid plexus epithelial cell: 207.8" "Group enriched" "Detected in many" 5 "Kidney Chromophobe (TCGA): 93.2;Testicular Germ Cell Tumor (TCGA): 33.6" "Region enriched" "Detected in all" 8 "choroid plexus: 39.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Macrophages, Breast - Breast glandular cells, Colon - Colon enterocytes, Minor Salivary Gland - Minor salivary gland ductal cells, Skin - Eccrine sweat gland cells, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA029708 Uncertain Approved "Nucleoli fibrillar center,Mitochondria" Yes NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 1 "Nucleoli fibrillar center" Mitochondria "HPA029708: " "unprognostic (1.08e-1)" "unprognostic (4.27e-2)" "unprognostic (1.31e-1)" "unprognostic (2.15e-1)" "unprognostic (2.75e-1)" "unprognostic (4.98e-2)" "unprognostic (3.25e-1)" "unprognostic (7.35e-3)" "unprognostic (8.53e-2)" "unprognostic (4.18e-2)" "unprognostic (5.55e-2)" "unprognostic (3.22e-1)" "unprognostic (3.05e-1)" "unprognostic (4.68e-2)" "unprognostic (6.00e-2)" "unprognostic (1.22e-1)" "unprognostic (8.24e-3)" "unprognostic (1.60e-1)" "unprognostic (3.83e-3)" "unprognostic (1.24e-1)" "potential prognostic unfavorable (8.41e-4)" "unprognostic (2.19e-1)" "unprognostic (1.91e-1)" "unprognostic (2.73e-1)" "unprognostic (8.34e-2)" "unprognostic (1.02e-1)" "unprognostic (1.14e-1)" "unprognostic (2.70e-1)" "unprognostic (1.00e-2)" "unprognostic (1.14e-2)" TFDP1 "DILC, Dp-1, DP1, DRTF1" ENSG00000198176 "Transcription factor Dp-1" Q14186 13 113584721-113641473 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 154.7" "Cell type enhanced" "Detected in all" "Erythrocyte progenitors: 376.7;Neutrophils: 348.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "basophil: 32.0" "Lineage enriched" "Detected in all" 5 "granulocytes: 32.0" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033605, HPA044754, HPA068909, HPA077304" Enhanced Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 44: Non-specific - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 71 Nucleoplasm "Nuclear membrane, Cytosol" "CAB033605: , HPA044754: , HPA068909: , HPA077304: " "unprognostic (3.83e-1)" "unprognostic (9.66e-2)" "unprognostic (1.29e-1)" "unprognostic (4.62e-2)" "unprognostic (2.41e-1)" "unprognostic (1.41e-1)" "unprognostic (1.53e-2)" "unprognostic (3.04e-3)" "unprognostic (1.54e-1)" "unprognostic (8.50e-3)" "potential prognostic favorable (2.22e-6)" "unprognostic (6.45e-2)" "unprognostic (1.51e-1)" "validated prognostic unfavorable (3.42e-4)" "validated prognostic unfavorable (1.14e-4)" "validated prognostic unfavorable (2.71e-4)" "validated prognostic unfavorable (2.69e-5)" "unprognostic (2.39e-2)" "unprognostic (1.56e-1)" "unprognostic (3.38e-2)" "unprognostic (1.45e-1)" "unprognostic (3.93e-2)" "unprognostic (1.24e-1)" "unprognostic (2.70e-2)" "unprognostic (1.41e-1)" "unprognostic (8.25e-2)" "unprognostic (8.10e-2)" "unprognostic (1.14e-2)" "unprognostic (2.25e-1)" "unprognostic (2.31e-1)" "unprognostic (1.67e-1)" TFDP2 Dp-2 ENSG00000114126 "Transcription factor Dp-2" Q14188 3 141944428-142149544 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 157.9" "Cell type enhanced" "Detected in all" "Early spermatids: 1042.2;Late primary spermatocytes: 801.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018396, HPA070399" Supported Supported "Nucleoplasm,Vesicles,Mitotic spindle" Yes No "Cluster 22: Eosinophils - Transcription" "Cluster 80: Thymus - Adaptive immune response" "Cluster 25: Non-specific - Transcription" "Cluster 59: Leukemia - T-cell receptor" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 17 Nucleoplasm "Vesicles, Mitotic spindle" "CAB018396: , HPA070399: " "unprognostic (3.17e-1)" "unprognostic (1.53e-2)" "unprognostic (3.59e-1)" "unprognostic (4.44e-2)" "unprognostic (1.49e-1)" "unprognostic (2.88e-1)" "unprognostic (1.81e-2)" "potential prognostic favorable (5.07e-4)" "unprognostic (1.65e-1)" "unprognostic (4.28e-3)" "unprognostic (7.58e-3)" "unprognostic (3.53e-3)" "unprognostic (1.77e-1)" "validated prognostic unfavorable (8.44e-6)" "validated prognostic unfavorable (5.85e-4)" "unprognostic (3.62e-1)" "unprognostic (8.15e-2)" "unprognostic (1.67e-1)" "unprognostic (1.53e-1)" "unprognostic (7.64e-2)" "unprognostic (3.21e-3)" "unprognostic (1.63e-3)" "unprognostic (1.95e-2)" "unprognostic (1.48e-1)" "potential prognostic favorable (1.93e-4)" "unprognostic (1.03e-1)" "unprognostic (8.22e-2)" "unprognostic (1.39e-1)" "unprognostic (3.49e-1)" "unprognostic (2.58e-1)" "unprognostic (1.65e-1)" TFDP3 "CT30, E2F-like, HCA661" ENSG00000183434 "Transcription factor Dp family member 3" Q5H9I0 X 133216662-133218354 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 35 "testis: 3.9" "Group enriched" "Detected in some" 23 "Differentiating spermatogonia: 26.7;Early primary spermatocytes: 26.3;Undifferentiated spermatogonia: 31.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Testicular Germ Cell Tumor (TCGA): 1.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "liver cancer: 1.3;Sarcoma: 1.0" "Skin - Eccrine sweat gland cells, Testis - Spermatogonia" HPA077304 Supported "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 5 "Nucleoplasm, Nuclear membrane" Cytosol "HPA077304: " "unprognostic (1.57e-1)" "unprognostic (9.51e-2)" "unprognostic (1.72e-1)" TFE3 "bHLHe33, TFEA" ENSG00000068323 "Transcription factor binding to IGHM enhancer 3" P19532 X 49028726-49043410 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Adaptive immunity, Immunity, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant, Intellectual disability, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 187.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 12.6" "Group enriched" "Detected in many" 4 "granulocytes: 12.6;monocytes: 6.3" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023881 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 12 "Nucleoplasm, Cytosol" "HPA023881: " "unprognostic (7.21e-2)" "unprognostic (4.86e-2)" "unprognostic (1.05e-1)" "unprognostic (7.14e-2)" "unprognostic (1.05e-1)" "unprognostic (1.14e-1)" "unprognostic (1.03e-1)" "unprognostic (9.37e-2)" "unprognostic (8.64e-2)" "unprognostic (2.43e-1)" "unprognostic (4.13e-2)" "unprognostic (1.85e-3)" "potential prognostic unfavorable (9.57e-4)" "potential prognostic unfavorable (1.79e-5)" "unprognostic (1.22e-2)" "unprognostic (7.29e-3)" "unprognostic (1.44e-1)" "unprognostic (2.52e-2)" "unprognostic (1.40e-1)" "unprognostic (2.77e-2)" "unprognostic (2.54e-1)" "unprognostic (8.11e-2)" "unprognostic (1.30e-2)" "unprognostic (2.45e-2)" "unprognostic (1.17e-1)" "unprognostic (6.39e-2)" "unprognostic (1.83e-1)" "unprognostic (8.28e-2)" "unprognostic (2.88e-2)" "unprognostic (3.73e-2)" "unprognostic (1.03e-1)" TFEB "bHLHe35, TCFEB" ENSG00000112561 "Transcription factor EB" P19484 6 41683978-41736259 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Adaptive immunity, Autophagy, Immunity, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 76.5" "Cell type enhanced" "Detected in many" "B-cells: 110.8;Neutrophils: 137.6;Oligodendrocytes: 171.6;Renal collecting duct intercalated cells: 111.6;Syncytiotrophoblasts: 138.8" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 101.2;committed oligodendrocyte precursor: 132.0;oligodendrocyte: 207.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 16.1;eosinophil: 17.0;intermediate monocyte: 16.4;memory B-cell: 34.3;myeloid DC: 14.8;naive B-cell: 22.7;neutrophil: 47.5;non-classical monocyte: 14.2" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "lymphoma: 44.7" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067082 Supported Cytosol NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 55: Lymphoma - Immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 9 Cytosol "HPA067082: " "unprognostic (1.54e-1)" "potential prognostic favorable (9.05e-4)" "unprognostic (1.06e-1)" "unprognostic (4.40e-3)" "unprognostic (3.76e-1)" "unprognostic (2.95e-2)" "unprognostic (9.97e-2)" "unprognostic (3.81e-3)" "unprognostic (1.47e-1)" "unprognostic (1.01e-1)" "potential prognostic favorable (3.93e-8)" "unprognostic (7.49e-3)" "unprognostic (4.60e-3)" "unprognostic (1.16e-1)" "unprognostic (3.03e-1)" "unprognostic (2.64e-3)" "unprognostic (3.02e-2)" "unprognostic (9.96e-2)" "unprognostic (5.82e-2)" "unprognostic (3.71e-2)" "unprognostic (3.87e-1)" "unprognostic (8.04e-3)" "unprognostic (7.10e-3)" "unprognostic (8.49e-2)" "unprognostic (1.67e-1)" "unprognostic (2.81e-2)" "unprognostic (3.14e-3)" "unprognostic (1.59e-1)" "unprognostic (1.32e-3)" "unprognostic (8.07e-2)" "unprognostic (2.48e-2)" TFEC "bHLHe34, TCFEC, TFECL" ENSG00000105967 "Transcription factor EC" O14948 7 115935148-116159896 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 16.2;kidney: 19.1;lymphoid tissue: 20.6" "Cell type enhanced" "Detected in many" "B-cells: 130.0;cDC: 93.8;Hematopoietic stem cells: 165.9;Hofbauer cells: 86.7;Kupffer cells: 152.7;Macrophages: 218.1;Megakaryocyte progenitors: 86.1;Microglia: 237.4;Monocyte progenitors: 204.7;monocytes: 176.8;Neutrophil progenitors: 81.4;pDCs: 115.6;Proximal tubule cells: 84.0" "Cell type enriched" "Detected in some" 13 "central nervous system macrophage: 315.3" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 15.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "classical monocyte: 7.1;intermediate monocyte: 2.8;memory B-cell: 3.8;myeloid DC: 6.3;naive B-cell: 2.5;plasmacytoid DC: 3.3" "Group enriched" "Detected in many" 29 "B-cells: 3.8;dendritic cells: 6.3;monocytes: 7.1" "Group enriched" "Detected in some" 13 "Leukemia: 12.5;lymphoma: 21.4;Rhabdoid: 6.6" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Kupffer cells, Lung - Macrophages, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB032260, HPA050528, HPA063577" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 3 Nucleoplasm Cytosol "CAB032260: , HPA050528: , HPA063577: " "unprognostic (2.57e-1)" "unprognostic (1.01e-1)" "unprognostic (1.90e-2)" "unprognostic (9.86e-3)" "unprognostic (6.54e-2)" "unprognostic (1.62e-1)" "unprognostic (7.37e-2)" "unprognostic (1.82e-1)" "unprognostic (4.71e-2)" "potential prognostic favorable (1.89e-7)" "unprognostic (7.76e-3)" "unprognostic (7.05e-3)" "unprognostic (1.32e-1)" "unprognostic (9.83e-3)" "unprognostic (5.99e-2)" "unprognostic (1.09e-1)" "unprognostic (4.23e-1)" "unprognostic (1.34e-1)" "unprognostic (8.23e-2)" "unprognostic (3.18e-1)" "unprognostic (1.68e-2)" "unprognostic (8.69e-3)" "unprognostic (3.01e-1)" "unprognostic (2.33e-2)" "unprognostic (1.74e-1)" TFF1 "BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2" ENSG00000160182 "Trefoil factor 1" P04155 21 42362282-42366535 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 48 "stomach 1: 7508.8" "Cell type enriched" "Detected in many" 11 "Foveolar cells: 32436.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Pancreatic Adenocarcinoma (TCGA): 1839.0;Stomach Adenocarcinoma (TCGA): 1448.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 10 "breast cancer: 1444.6" "Colon - Colon enterocytes, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Ductal cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB002170, HPA003425" Enhanced "Secreted to digestive system" "Growth factor" NA NA 1700000 "Cluster 60: Stomach - Digestion" "Cluster 27: Breast cancer - Unknown function" "Cluster 68: Foveolar cells - Mucosal defense" 9 "CAB002170: , HPA003425: " "unprognostic (3.30e-2)" "unprognostic (2.05e-3)" "unprognostic (4.07e-2)" "unprognostic (2.17e-1)" "unprognostic (2.88e-2)" "unprognostic (5.78e-2)" "unprognostic (4.40e-1)" "potential prognostic unfavorable (2.96e-9)" "unprognostic (2.78e-3)" "potential prognostic unfavorable (8.84e-4)" "unprognostic (1.50e-3)" "unprognostic (2.65e-1)" "unprognostic (5.66e-2)" "unprognostic (3.57e-1)" "unprognostic (4.55e-1)" "unprognostic (1.36e-1)" "unprognostic (2.07e-2)" "unprognostic (7.80e-2)" "unprognostic (1.56e-1)" "unprognostic (2.68e-3)" "unprognostic (1.86e-1)" "unprognostic (8.82e-2)" "unprognostic (3.73e-1)" TFF2 SML1 ENSG00000160181 "Trefoil factor 2" Q03403 21 42346357-42350997 "Cancer-related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "stomach 1: 6462.6" "Cell type enriched" "Detected in some" 6 "Foveolar cells: 11062.6" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Pancreatic Adenocarcinoma (TCGA): 759.9;Stomach Adenocarcinoma (TCGA): 520.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "Gastric cancer: 75.2;pancreatic cancer: 79.8" "Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Ductal cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB025834, HPA036705" Enhanced "Secreted to digestive system" "No annotated function" NA NA 730000 "Cluster 60: Stomach - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 68: Foveolar cells - Mucosal defense" 8 "CAB025834: , HPA036705: " "unprognostic (5.49e-1)" "unprognostic (1.66e-1)" "unprognostic (3.91e-1)" "unprognostic (1.62e-1)" "unprognostic (1.71e-2)" "validated prognostic unfavorable (1.75e-4)" "validated prognostic unfavorable (6.49e-6)" "unprognostic (6.36e-1)" "unprognostic (6.11e-1)" "unprognostic (1.66e-1)" "unprognostic (2.19e-2)" "unprognostic (8.56e-3)" "unprognostic (4.77e-2)" "unprognostic (1.37e-1)" "unprognostic (2.16e-1)" "unprognostic (1.28e-3)" "unprognostic (1.13e-1)" "unprognostic (4.12e-1)" TFF3 "HITF, ITF" ENSG00000160180 "Trefoil factor 3" Q07654 21 42311667-42315409 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "cervix: 434.3;intestine: 509.9;salivary gland: 533.9;thyroid gland: 558.7" "Cell type enriched" "Detected in many" 19 "Goblet cells: 56753.5" "Group enriched" "Detected in some" 7 "ependymal cell: 1.6;fibroblast: 4.4;pericyte: 1.1" "Cancer enhanced" "Detected in all" "Colon Adenocarcinoma (TCGA): 717.7" "Region enriched" "Detected in single" 6 "midbrain: 4.6" "Immune cell enriched" "Detected in single" 16 "eosinophil: 1.6" "Lineage enriched" "Detected in single" 16 "granulocytes: 1.6" "Cancer enhanced" "Detected in many" "breast cancer: 357.7;colorectal cancer: 184.6" "Adipose subcutaneous - Smooth muscle cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Skeletal muscle - Smooth muscle cells" "Region enriched" "Detected in single" 15 "cerebellum: 1.5" "Not detected" "Not detected" "CAB020681, HPA035464" Enhanced Approved Nucleoplasm,Nucleoli "Secreted to blood" "No annotated function" No NA 151000000 4200000 "Cluster 77: Intestine - Digestion" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 70: Intestinal goblet cells - Mucin production" 5 Nucleoplasm Nucleoli "CAB020681: , HPA035464: " "unprognostic (1.55e-1)" "unprognostic (7.58e-2)" "unprognostic (1.85e-2)" "unprognostic (4.83e-3)" "unprognostic (4.19e-2)" "unprognostic (2.51e-2)" "unprognostic (2.20e-2)" "unprognostic (6.03e-2)" "unprognostic (3.60e-1)" "unprognostic (4.56e-2)" "potential prognostic favorable (2.11e-5)" "unprognostic (1.81e-1)" "unprognostic (1.46e-1)" "potential prognostic favorable (9.38e-4)" "unprognostic (6.18e-2)" "unprognostic (2.98e-1)" "unprognostic (2.10e-1)" "unprognostic (3.35e-1)" "unprognostic (9.04e-2)" "unprognostic (3.66e-2)" "unprognostic (3.68e-1)" "unprognostic (1.42e-3)" "unprognostic (7.28e-2)" "unprognostic (1.77e-1)" "potential prognostic unfavorable (4.36e-5)" "unprognostic (1.61e-1)" "unprognostic (2.77e-1)" "unprognostic (2.45e-1)" "unprognostic (1.61e-2)" "unprognostic (7.17e-3)" TFG "FLJ36137, SPG57, TF6" ENSG00000114354 "Trafficking from ER to golgi regulator" Q92734 3 100709295-100748964 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, Transport" "Cancer-related genes, Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Neuropathy, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 402.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019473, HPA052206" Approved Approved Vesicles,Cytosol No No 170000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 63 Vesicles Cytosol "HPA019473: , HPA052206: " "unprognostic (3.97e-1)" "unprognostic (1.49e-2)" "unprognostic (1.05e-1)" "unprognostic (8.89e-2)" "unprognostic (2.56e-1)" "unprognostic (1.91e-1)" "unprognostic (2.26e-1)" "unprognostic (7.55e-2)" "unprognostic (1.22e-2)" "unprognostic (6.85e-3)" "unprognostic (1.04e-2)" "potential prognostic unfavorable (7.60e-7)" "unprognostic (3.11e-1)" "potential prognostic unfavorable (2.60e-6)" "unprognostic (2.24e-2)" "unprognostic (1.42e-3)" "unprognostic (6.17e-3)" "unprognostic (1.52e-1)" "unprognostic (4.32e-2)" "unprognostic (1.84e-1)" "unprognostic (7.92e-2)" "potential prognostic unfavorable (5.06e-4)" "unprognostic (1.38e-2)" "unprognostic (2.57e-2)" "unprognostic (1.77e-2)" "unprognostic (1.68e-1)" "unprognostic (1.77e-1)" "unprognostic (1.08e-1)" "unprognostic (1.28e-1)" "unprognostic (2.28e-1)" "unprognostic (2.63e-1)" TFIP11 "DKFZP434B194, Spp382, TIP39" ENSG00000100109 "Tuftelin interacting protein 11" Q9UBB9 22 26491225-26512505 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Biomineralization, mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 107.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Prostate basal glandular cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027085 Approved Nucleoplasm,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 66: Non-specific - Mitochondria" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 262 Nucleoplasm Cytosol "HPA027085: " "unprognostic (1.40e-1)" "unprognostic (3.49e-2)" "unprognostic (2.85e-2)" "unprognostic (1.39e-2)" "unprognostic (9.87e-2)" "unprognostic (1.88e-1)" "unprognostic (1.96e-1)" "unprognostic (4.86e-3)" "unprognostic (8.63e-2)" "unprognostic (6.05e-2)" "validated prognostic favorable (3.36e-5)" "validated prognostic favorable (8.41e-4)" "unprognostic (2.41e-1)" "unprognostic (7.76e-2)" "unprognostic (1.53e-1)" "unprognostic (1.39e-1)" "unprognostic (2.06e-2)" "unprognostic (3.37e-2)" "unprognostic (1.75e-3)" "unprognostic (2.11e-1)" "unprognostic (5.87e-2)" "unprognostic (1.46e-1)" "unprognostic (6.32e-2)" "unprognostic (1.03e-1)" "unprognostic (7.21e-3)" "unprognostic (1.60e-1)" "unprognostic (3.60e-1)" "unprognostic (7.28e-2)" "unprognostic (1.58e-1)" "unprognostic (1.14e-1)" "unprognostic (4.44e-2)" TFPI "EPI, LACI, TFI, TFPI1" ENSG00000003436 "Tissue factor pathway inhibitor" P10646 2 187464230-187565760 "Candidate cardiovascular disease genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Protease inhibitor, Serine protease inhibitor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 254.3;placenta: 179.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 669.1;Extravillous trophoblasts: 3874.2;Hematopoietic stem cells: 510.9;Hepatocytes: 593.6;Lymphatic endothelial cells: 2526.5;Myosatellite cells: 516.6;Pericytes: 509.3;Syncytiotrophoblasts: 1286.4" "Group enriched" "Detected in many" 4 "fibroblast: 151.6;pericyte: 575.2;vascular associated smooth muscle cell: 159.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA005575, CAB020842" Supported "Secreted to blood" "Blood coagulation" NA NA 58100000 88000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 23: Choroid plexus - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 1 "CAB020842: , HPA005575: " "unprognostic (1.88e-1)" "unprognostic (1.54e-1)" "unprognostic (1.30e-1)" "unprognostic (1.60e-3)" "unprognostic (4.89e-2)" "unprognostic (1.89e-1)" "unprognostic (3.11e-1)" "unprognostic (2.44e-1)" "unprognostic (6.68e-2)" "unprognostic (8.07e-2)" "unprognostic (3.54e-3)" "unprognostic (2.37e-1)" "unprognostic (2.25e-1)" "unprognostic (8.07e-2)" "unprognostic (2.15e-1)" "unprognostic (3.50e-2)" "unprognostic (1.61e-1)" "unprognostic (9.89e-3)" "unprognostic (2.86e-1)" "unprognostic (1.25e-1)" "unprognostic (2.40e-1)" "unprognostic (5.08e-3)" "unprognostic (6.37e-2)" "unprognostic (6.57e-2)" "unprognostic (2.12e-2)" "unprognostic (3.11e-2)" "unprognostic (7.48e-3)" "unprognostic (1.32e-2)" "unprognostic (1.09e-1)" "unprognostic (1.59e-2)" "unprognostic (1.38e-1)" TFPI2 "PP5, REF1, TFPI-2" ENSG00000105825 "Tissue factor pathway inhibitor 2" P48307 7 93885396-93890753 "Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "placenta: 899.6" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 437.7;Endometrial luminal cells: 755.7;Epididymal basal cells: 2412.4;Extravillous trophoblasts: 340.7;Fallopian secretory cells: 406.3;Pancreatic duct cells: 1122.9;Syncytiotrophoblasts: 2540.6" "Cell type enhanced" "Detected in some" "endothelial cell: 9.8;fibroblast: 24.7;pericyte: 10.2" "Group enriched" "Detected in all" 5 "Kidney Renal Papillary Cell Carcinoma (TCGA): 484.0;Lung Adenocarcinoma (TCGA): 201.1" "Region enhanced" "Detected in many" "medulla oblongata: 10.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "thyroid cancer: 919.6" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Mesothelial cells, Liver - Vascular endothelial cells, Pancreas - Ductal cells" "Not detected" "Not detected" "Region enhanced" "Detected in all" "spinal cord: 40.4" "CAB010142, HPA049158, HPA070525" Enhanced "Secreted to extracellular matrix" "Blood coagulation" NA NA 130000 "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 46: Brainstem - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." "CAB010142: , HPA049158: , HPA070525: " "unprognostic (1.43e-1)" "potential prognostic favorable (5.09e-5)" "unprognostic (1.21e-1)" "unprognostic (1.16e-1)" "unprognostic (9.56e-2)" "unprognostic (2.96e-2)" "unprognostic (9.23e-3)" "unprognostic (2.79e-3)" "unprognostic (3.31e-2)" "unprognostic (2.16e-2)" "validated prognostic unfavorable (3.87e-5)" "validated prognostic unfavorable (5.64e-4)" "unprognostic (1.90e-1)" "unprognostic (1.57e-1)" "unprognostic (4.51e-2)" "unprognostic (5.27e-2)" "unprognostic (5.78e-2)" "unprognostic (1.27e-3)" "unprognostic (6.04e-3)" "unprognostic (2.25e-2)" "unprognostic (1.64e-1)" "unprognostic (5.58e-2)" "potential prognostic unfavorable (1.56e-4)" "unprognostic (5.98e-2)" "unprognostic (1.85e-1)" "unprognostic (1.35e-1)" "unprognostic (1.10e-3)" "unprognostic (3.11e-3)" "unprognostic (1.08e-1)" "unprognostic (2.36e-1)" "unprognostic (8.91e-2)" TFPT "amida, FB1, INO80F" ENSG00000105619 "TCF3 fusion partner" P0C1Z6 19 54107020-54115657 "Disease related genes, Predicted intracellular proteins" "Apoptosis, DNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "brain: 90.2" "Cell type enhanced" "Detected in many" "Gastric chief cells: 65.5;Hofbauer cells: 154.3;Megakaryocytes: 61.8;Mucous neck cells: 46.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034958, HPA058534" Approved Supported Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 78: Brain - Neuronal signaling" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 4: Non-specific - Transcription" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 85 Nucleoplasm "HPA034958: , HPA058534: " "unprognostic (2.56e-1)" "unprognostic (1.65e-1)" "unprognostic (3.26e-2)" "unprognostic (6.18e-3)" "unprognostic (1.79e-1)" "unprognostic (2.41e-1)" "unprognostic (1.63e-1)" "unprognostic (1.12e-1)" "unprognostic (1.81e-1)" "unprognostic (1.38e-2)" "unprognostic (2.66e-1)" "unprognostic (1.17e-2)" "unprognostic (3.86e-2)" "unprognostic (4.65e-3)" "unprognostic (2.00e-2)" "unprognostic (2.78e-1)" "unprognostic (1.83e-1)" "unprognostic (1.49e-1)" "unprognostic (5.23e-1)" "unprognostic (2.38e-1)" "unprognostic (1.91e-1)" "unprognostic (9.38e-3)" "unprognostic (3.03e-2)" "unprognostic (2.13e-2)" "unprognostic (3.96e-1)" "unprognostic (2.60e-1)" "unprognostic (5.99e-2)" "unprognostic (3.18e-2)" "unprognostic (5.37e-2)" "unprognostic (2.50e-1)" "unprognostic (1.56e-1)" TFR2 "HFE3, TFRC2" ENSG00000106327 "Transferrin receptor 2" Q9UP52 7 100620416-100642779 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Transporters" Receptor "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "liver: 313.5" "Cell type enhanced" "Detected in many" "Early spermatids: 68.0;Erythrocyte progenitors: 236.0;Hepatocytes: 531.0;Megakaryocyte progenitors: 40.9;Megakaryocyte-Erythroid progenitors: 125.9;Parietal cells: 47.7" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in some" 164 "Liver Hepatocellular Carcinoma (TCGA): 184.1" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 23 "basophil: 2.5;eosinophil: 1.9" "Lineage enriched" "Detected in single" 26 "granulocytes: 2.5" "Cancer enriched" "Detected in some" 7 "Leukemia: 23.6" "Liver - Hepatocytes, Spleen - Erythrocytes, Stomach - Parietal cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB016255, HPA017171, HPA073125" Enhanced Approved "Golgi apparatus" NA NA 1400000 "Cluster 46: Basophils - Proteolysis" "Cluster 53: Liver - Plasma proteins" "Cluster 15: Non-specific - Transcription" "Cluster 47: Leukemia - Hemostasis" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 4 "Golgi apparatus" "CAB016255: , HPA017171: , HPA073125: " "unprognostic (1.14e-2)" "unprognostic (4.07e-2)" "unprognostic (2.15e-2)" "unprognostic (4.51e-3)" "unprognostic (1.07e-1)" "unprognostic (3.31e-2)" "unprognostic (4.06e-2)" TFRC "CD71, p90, TFR1" ENSG00000072274 "Transferrin receptor" P02786 3 196012511-196082153 "Cancer-related genes, CD markers, Disease related genes, Enzymes, Essential proteins, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Endocytosis, Host-virus interaction" "Host cell receptor for virus entry, Receptor, Transducer" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythrocyte progenitors: 1607.6;Macrophages: 398.1;monocytes: 409.6;Syncytiotrophoblasts: 710.3" "Cell type enriched" "Detected in all" 6 "endothelial cell: 425.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 9.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000153, HPA028598" Enhanced Supported Endosomes,Lysosomes "Secreted to blood" Receptor NA NA 1310000000 140000000 "Cluster 13: Non-specific - Mitochondria" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 139 "Endosomes, Lysosomes" "CAB000153: , HPA028598: " "unprognostic (1.60e-2)" "unprognostic (3.39e-2)" "unprognostic (5.13e-2)" "potential prognostic unfavorable (1.85e-4)" "unprognostic (2.38e-1)" "unprognostic (1.11e-1)" "unprognostic (8.70e-2)" "potential prognostic unfavorable (1.03e-4)" "unprognostic (5.60e-2)" "potential prognostic unfavorable (5.77e-4)" "unprognostic (3.95e-3)" "unprognostic (1.14e-1)" "unprognostic (1.88e-2)" "validated prognostic unfavorable (9.59e-6)" "validated prognostic unfavorable (4.51e-6)" "unprognostic (2.55e-2)" "unprognostic (8.36e-3)" "unprognostic (1.66e-2)" "potential prognostic favorable (9.13e-4)" "unprognostic (1.15e-2)" "unprognostic (9.70e-3)" "unprognostic (9.81e-3)" "unprognostic (6.19e-2)" "unprognostic (1.12e-2)" "unprognostic (2.82e-2)" "unprognostic (1.80e-2)" "unprognostic (9.43e-3)" "unprognostic (3.05e-2)" "unprognostic (5.45e-2)" "unprognostic (2.02e-3)" "unprognostic (7.72e-2)" TG "AITD3, TGN" ENSG00000042832 Thyroglobulin P01266 8 132866958-133134903 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Thyroid hormones biosynthesis" "Hormone, Thyroid hormone" "Cancer-related genes, Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 685 "thyroid gland: 8743.8" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 129.9;Hematopoietic stem cells: 54.3;Innate lymphoid cells: 106.8;Macrophages: 64.0;Mast cells: 56.9;monocytes: 53.7;Neutrophils: 322.5;NK-cells: 117.2;Salivary basal cells: 100.5;T-cells: 93.9" "Cell type enhanced" "Detected in many" "amygdala excitatory: 52.6;ependymal cell: 45.7;hippocampal CA4: 73.9" "Cancer enriched" "Detected in many" 1546 "Thyroid Carcinoma (TCGA): 11774.7" "Group enriched" "Detected in some" 4 "amygdala: 5.8;cerebral cortex: 3.8;choroid plexus: 3.1;hippocampal formation: 3.3" "Immune cell enhanced" "Detected in single" "neutrophil: 1.0" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in some" 9 "thyroid cancer: 16.6" "Prostate - Prostate basal glandular cells, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Region enriched" "Detected in single" 5 "cerebellum: 1.1" "Low region specificity" "Detected in many" "CAB000077, HPA002740, CAB056155" Enhanced "Secreted in other tissues" Hormone NA NA 870000 "Cluster 4: Neutrophils - Degranulation" "Cluster 33: Thyroid gland - Tissue development" "Cluster 29: Forebrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 2 "CAB000077: , CAB056155: , HPA002740: " "unprognostic (4.40e-2)" "unprognostic (7.94e-3)" "unprognostic (1.27e-1)" "unprognostic (1.42e-1)" "unprognostic (6.06e-3)" "unprognostic (3.93e-1)" "unprognostic (1.19e-1)" "unprognostic (2.10e-2)" "unprognostic (6.88e-3)" "unprognostic (1.24e-1)" "unprognostic (2.26e-1)" "unprognostic (1.63e-2)" "potential prognostic favorable (1.31e-5)" "unprognostic (2.02e-1)" "unprognostic (1.71e-1)" "unprognostic (8.50e-2)" TGDS "SDR2E1, TDPGD" ENSG00000088451 "TDP-glucose 4,6-dehydratase" O95455 13 94574054-94596242 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Lyase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039927, HPA040857" Approved Approved Nucleoplasm,Nucleoli,Cytosol NA No "Cluster 3: Non-specific - Nuclear processes" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 19: Non-specific - Unknown function" "Cluster 67: Plasma cells - Plasma cell differentiation" 2 Nucleoplasm "Nucleoli, Cytosol" "HPA039927: , HPA040857: " "unprognostic (1.74e-1)" "unprognostic (6.74e-2)" "unprognostic (3.00e-1)" "unprognostic (1.62e-1)" "unprognostic (3.93e-2)" "unprognostic (2.82e-1)" "unprognostic (2.12e-1)" "unprognostic (2.43e-1)" "unprognostic (4.98e-2)" "unprognostic (1.88e-1)" "potential prognostic favorable (6.58e-5)" "unprognostic (1.85e-2)" "unprognostic (4.23e-2)" "unprognostic (2.44e-1)" "unprognostic (6.99e-2)" "unprognostic (2.19e-1)" "unprognostic (6.22e-3)" "unprognostic (2.30e-1)" "unprognostic (9.32e-2)" "unprognostic (2.57e-1)" "unprognostic (1.80e-1)" "unprognostic (6.44e-2)" "unprognostic (8.28e-3)" "potential prognostic unfavorable (6.32e-5)" "unprognostic (1.36e-2)" "unprognostic (2.66e-1)" "unprognostic (3.75e-2)" "unprognostic (3.28e-2)" "unprognostic (9.41e-2)" "unprognostic (2.53e-1)" "unprognostic (1.42e-1)" TGFA ENSG00000163235 "Transforming growth factor alpha" P01135 2 70447284-70554193 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.5;esophagus: 24.0" "Cell type enhanced" "Detected in many" "Early spermatids: 145.7;Endometrial glandular cells: 116.4;Esophageal apical cells: 305.9;Neutrophils: 146.0;Pancreatic duct cells: 150.7;Urothelial cells: 180.9" "Cell type enhanced" "Detected in many" "oligodendrocyte: 56.1;oligodendrocyte precursor cell: 137.0" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 62.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 11.4;eosinophil: 23.9;neutrophil: 24.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 24.0" "Cancer enhanced" "Detected in many" "Kidney cancer: 179.0" "Spleen - Macrophages, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042297 Approved Approved Vesicles "Secreted to blood" "Growth factor" No No 57900 "Cluster 21: Neutrophils - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 15: Kidney cancer - Membrane components" "Cluster 24: Neutrophils - Innate immunity signal integration" 10 Vesicles "HPA042297: " "unprognostic (7.92e-2)" "unprognostic (1.04e-1)" "unprognostic (1.63e-1)" "unprognostic (1.77e-3)" "unprognostic (5.90e-2)" "unprognostic (3.55e-2)" "unprognostic (1.69e-1)" "unprognostic (1.11e-1)" "unprognostic (1.05e-2)" "unprognostic (9.47e-2)" "validated prognostic favorable (5.79e-10)" "validated prognostic favorable (6.64e-5)" "unprognostic (1.54e-1)" "unprognostic (1.31e-1)" "unprognostic (1.79e-1)" "unprognostic (8.19e-3)" "unprognostic (1.58e-2)" "unprognostic (1.48e-2)" "unprognostic (1.15e-2)" "unprognostic (6.84e-2)" "unprognostic (5.11e-2)" "potential prognostic unfavorable (2.31e-5)" "unprognostic (1.11e-2)" "unprognostic (1.90e-1)" "unprognostic (9.22e-2)" "unprognostic (7.00e-2)" "unprognostic (2.36e-2)" "unprognostic (7.47e-2)" "unprognostic (1.91e-1)" "unprognostic (1.00e-3)" "unprognostic (3.05e-1)" TGFB1 "CED, DPD1, TGFB, TGFbeta" ENSG00000105329 "Transforming growth factor beta 1" 19 41301587-41353922 "Human disease related genes, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 828.5;Innate lymphoid cells: 436.8;Megakaryocyte progenitors: 421.2;Megakaryocytes: 822.2;Neutrophils: 497.6;NK-cells: 520.5;pDCs: 484.2;Platelets: 2842.4;T-cells: 460.1" "Group enriched" "Detected in all" 4 "central nervous system macrophage: 197.4;leukocyte: 225.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 3.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000361, HPA073356" Approved Approved "Golgi apparatus,Plasma membrane,Basal body" "Secreted to blood" NA NA 1290000 "Cluster 45: Eosinophils - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 43: Hindbrain - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 20: Non-specific - Transcription regulation" 16 "Golgi apparatus, Plasma membrane" "Basal body" "CAB000361: , HPA073356: " "unprognostic (3.13e-2)" "unprognostic (4.28e-2)" "unprognostic (2.82e-1)" "unprognostic (1.98e-3)" "unprognostic (6.77e-3)" "unprognostic (1.62e-1)" "unprognostic (3.33e-2)" "unprognostic (4.14e-3)" "unprognostic (1.81e-3)" "unprognostic (2.75e-1)" "unprognostic (3.09e-2)" "unprognostic (1.02e-1)" "unprognostic (1.43e-3)" "unprognostic (1.23e-2)" "unprognostic (6.86e-2)" "unprognostic (4.84e-2)" "unprognostic (5.55e-3)" "unprognostic (3.78e-2)" "unprognostic (2.18e-2)" "unprognostic (1.70e-2)" "unprognostic (3.15e-1)" "unprognostic (1.04e-1)" "unprognostic (2.20e-2)" "unprognostic (3.02e-1)" "unprognostic (8.80e-2)" "unprognostic (4.49e-2)" "unprognostic (1.38e-2)" "unprognostic (9.53e-3)" "unprognostic (1.07e-2)" "unprognostic (9.84e-3)" "unprognostic (2.50e-2)" TGFB1I1 "ARA55, Hic-5, TSC-5" ENSG00000140682 "Transforming growth factor beta 1 induced transcript 1" O43294 16 31471585-31477960 "Predicted intracellular proteins" "Differentiation, Wnt signaling pathway" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 258.0;intestine: 251.1" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 279.9;Decidual stromal cells: 330.7;Hepatic stellate cells: 200.1;Megakaryocytes: 593.4;Ovarian stromal cells: 111.6;Pericytes: 144.9;Peritubular myoid cells: 160.6;Platelets: 211.1;Salivary myoepithelial cells: 95.0;Smooth muscle cells: 438.8;Vascular smooth muscle cells: 202.4" "Group enriched" "Detected in some" 5 "pericyte: 69.6;vascular associated smooth muscle cell: 100.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "basophil: 9.5" "Lineage enriched" "Detected in many" 6 "granulocytes: 9.5" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Colon - Smooth muscle cells, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020844, HPA072360" Enhanced Supported "Vesicles,Focal adhesion sites,Cytosol" NA NA 280000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 47: Endothelial cells - Vasculature" "Cluster 72: Neuronal - Signal transduction" "Cluster 62: Smooth muscle cells - Muscle contraction" 17 "Focal adhesion sites" "Vesicles, Cytosol" "CAB020844: , HPA072360: " "unprognostic (3.90e-1)" "unprognostic (6.92e-2)" "unprognostic (8.06e-2)" "unprognostic (2.15e-2)" "unprognostic (3.52e-2)" "unprognostic (2.20e-2)" "unprognostic (1.30e-1)" "unprognostic (4.98e-2)" "unprognostic (1.51e-1)" "unprognostic (7.73e-2)" "unprognostic (2.09e-2)" "unprognostic (2.25e-2)" "potential prognostic unfavorable (9.32e-4)" "unprognostic (2.23e-1)" "unprognostic (3.46e-2)" "unprognostic (1.67e-2)" "unprognostic (7.28e-3)" "unprognostic (2.82e-2)" "unprognostic (1.14e-1)" "potential prognostic unfavorable (4.86e-4)" "unprognostic (1.66e-1)" "unprognostic (1.34e-1)" "unprognostic (4.55e-2)" "unprognostic (6.69e-2)" "unprognostic (2.96e-2)" "unprognostic (2.51e-2)" "unprognostic (9.97e-2)" "unprognostic (4.27e-3)" "unprognostic (2.52e-1)" "unprognostic (2.04e-1)" "unprognostic (6.42e-2)" TGFB2 ENSG00000092969 "Transforming growth factor beta 2" P61812 1 218345336-218444619 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Growth factor, Mitogen" "Aortic aneurysm, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 129.5;Choroid plexus epithelial cells: 138.7;Ependymal cells: 145.5;Müller glia: 152.1;Myonuclei: 123.5;Pancreatic duct cells: 134.2;Pituicytes/FSCs: 195.8;Salivary acinar cells: 127.7;Salivary basal cells: 173.4;Salivary duct cells: 514.2;Salivary ionocytes: 132.8;Smooth muscle cells: 123.4" "Cell type enhanced" "Detected in many" "ependymal cell: 152.7" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 26.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 89.1" "Adipose subcutaneous - Adipose progenitor cells, Breast - Breast myoepithelial cells, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Ductal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006134 Approved Vesicles "Secreted to blood" "Growth factor" NA Yes 4890000 "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 72: Neuronal - Signal transduction" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 2 Vesicles "HPA006134: " "unprognostic (2.37e-1)" "unprognostic (1.81e-2)" "unprognostic (3.92e-1)" "unprognostic (3.21e-2)" "unprognostic (2.40e-2)" "unprognostic (4.64e-2)" "unprognostic (1.51e-1)" "unprognostic (4.85e-2)" "unprognostic (2.89e-1)" "potential prognostic favorable (9.65e-5)" "unprognostic (5.07e-2)" "unprognostic (6.78e-2)" "unprognostic (7.83e-2)" "unprognostic (8.58e-2)" "unprognostic (3.21e-2)" "unprognostic (1.28e-1)" "unprognostic (7.55e-2)" "unprognostic (1.75e-1)" "unprognostic (3.36e-1)" "unprognostic (1.70e-2)" "unprognostic (1.02e-2)" "unprognostic (1.69e-2)" "unprognostic (7.17e-2)" "unprognostic (2.81e-2)" "unprognostic (1.95e-1)" "unprognostic (1.74e-2)" "unprognostic (2.90e-3)" "unprognostic (1.67e-1)" "unprognostic (1.70e-1)" "unprognostic (9.51e-2)" TGFB3 "ARVD, ARVD1" ENSG00000119699 "Transforming growth factor beta 3" P10600 14 75958097-75983011 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Growth factor, Mitogen" "Cancer-related genes, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 35.1;Fibroblasts: 34.6;Hepatic stellate cells: 64.5;Late spermatids: 72.4;Leydig cells: 29.7;Pericytes: 50.4;Prostatic glandular cells: 73.1;Vascular smooth muscle cells: 40.1" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 35.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 23.8" "Adipose subcutaneous - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027923 Approved "Nucleoplasm,Vesicles,Centriolar satellite,Basal body" "Secreted to blood" "Growth factor" NA NA 44800 "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 11: White matter - Signal transduction" "Cluster 27: Breast cancer - Unknown function" "Cluster 108: Fibroblasts - ECM organization" 4 Vesicles "Nucleoplasm, Centriolar satellite, Basal body" "HPA027923: " "unprognostic (3.05e-2)" "unprognostic (4.03e-2)" "unprognostic (4.08e-1)" "unprognostic (2.10e-1)" "unprognostic (6.71e-2)" "unprognostic (3.02e-2)" "unprognostic (2.19e-1)" "unprognostic (4.21e-2)" "unprognostic (1.73e-1)" "unprognostic (1.60e-2)" "unprognostic (6.98e-2)" "unprognostic (8.70e-3)" "potential prognostic unfavorable (7.03e-4)" "unprognostic (5.10e-2)" "unprognostic (1.32e-1)" "unprognostic (9.40e-2)" "unprognostic (8.76e-2)" "unprognostic (1.53e-1)" "unprognostic (1.42e-1)" "unprognostic (3.25e-2)" "potential prognostic unfavorable (1.42e-4)" "unprognostic (4.95e-2)" "unprognostic (2.22e-1)" "unprognostic (1.30e-1)" "unprognostic (2.21e-3)" "unprognostic (7.83e-2)" "unprognostic (1.35e-1)" "unprognostic (5.82e-3)" "unprognostic (8.71e-2)" "unprognostic (1.91e-2)" "unprognostic (1.57e-1)" TGFBI "BIGH3, CDB1, CDGG1, CSD1, CSD2, CSD3, LCD1" ENSG00000120708 "Transforming growth factor beta induced" Q15582 5 136028988-136063818 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion, Sensory transduction, Vision" "Amyloidosis, Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 469.7;placenta: 429.3" "Cell type enhanced" "Detected in many" "cDC: 156.6;Decidual stromal cells: 128.6;Hepatic stellate cells: 335.6;Kupffer cells: 387.4;Macrophages: 323.1;monocytes: 239.1;Myosatellite cells: 181.6;Ocular epithelial cells: 1309.1;pDCs: 214.7;Pericytes: 130.7" "Group enriched" "Detected in many" 4 "central nervous system macrophage: 16.3;choroid plexus epithelial cell: 21.6;fibroblast: 15.6;leukocyte: 23.6;vascular associated smooth muscle cell: 29.3" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 1198.6" "Group enriched" "Detected in all" 7 "choroid plexus: 87.4;thalamus: 150.1" "Group enriched" "Detected in many" 32 "classical monocyte: 252.5;intermediate monocyte: 149.2;myeloid DC: 157.2;non-classical monocyte: 121.9;plasmacytoid DC: 325.2" "Group enriched" "Detected in all" 46 "dendritic cells: 325.2;monocytes: 252.5" "Cancer enhanced" "Detected in all" "Kidney cancer: 2635.3" "Adrenal gland - Macrophages, Heart muscle - Fibroblasts, Pituitary gland - Fibroblasts, Prostate - Fibroblasts, Spleen - Macrophages, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008612, HPA017019" Enhanced "Secreted to blood" "Cell adhesion" NA NA 1400000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 12: Non-specific - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 100: Stratified epithelial cells - Barrier functions" 6 "HPA008612: , HPA017019: " "unprognostic (2.51e-2)" "unprognostic (4.11e-2)" "unprognostic (1.27e-1)" "potential prognostic unfavorable (2.21e-4)" "unprognostic (3.71e-1)" "unprognostic (8.80e-2)" "unprognostic (4.46e-3)" "unprognostic (7.77e-3)" "unprognostic (4.39e-3)" "unprognostic (6.03e-2)" "potential prognostic unfavorable (3.21e-5)" "unprognostic (4.62e-3)" "unprognostic (1.65e-1)" "unprognostic (1.40e-1)" "unprognostic (1.72e-1)" "unprognostic (4.87e-3)" "potential prognostic unfavorable (1.30e-4)" "unprognostic (4.34e-2)" "unprognostic (1.80e-3)" "potential prognostic unfavorable (4.81e-5)" "unprognostic (1.40e-1)" "unprognostic (3.75e-3)" "unprognostic (1.17e-2)" "unprognostic (3.67e-1)" "unprognostic (9.72e-2)" "unprognostic (1.04e-1)" "unprognostic (5.64e-2)" "unprognostic (4.87e-2)" "unprognostic (3.42e-2)" "unprognostic (1.72e-1)" "unprognostic (2.39e-2)" TGFBR1 "ACVRLK4, ALK-5, ALK5, ESS1, MSSE, TBR-i, TBRI" ENSG00000106799 "Transforming growth factor beta receptor 1" P36897 9 99104038-99154192 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Differentiation, Growth regulation" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglia: 420.0;Neutrophil progenitors: 220.0;Neutrophils: 230.5;Renal collecting duct principal cells: 288.6" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 557.5;leukocyte: 233.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 123.2" "Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002441, CAB031481, HPA056473" Uncertain Approved "Plasma membrane,Primary cilium,Primary cilium tip" "Intracellular and membrane" Receptor NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 49 "Plasma membrane, Primary cilium" "Primary cilium tip" "CAB002441: , CAB031481: , HPA056473: " "unprognostic (4.08e-1)" "unprognostic (1.58e-2)" "unprognostic (1.85e-3)" "unprognostic (2.01e-3)" "unprognostic (2.31e-2)" "unprognostic (2.50e-2)" "unprognostic (6.29e-2)" "unprognostic (1.33e-1)" "unprognostic (4.54e-2)" "unprognostic (1.20e-1)" "potential prognostic favorable (1.07e-6)" "unprognostic (2.16e-3)" "unprognostic (4.45e-2)" "unprognostic (2.98e-2)" "unprognostic (2.70e-2)" "unprognostic (1.49e-2)" "unprognostic (4.97e-2)" "unprognostic (6.75e-3)" "unprognostic (1.61e-1)" "unprognostic (4.40e-2)" "potential prognostic unfavorable (6.87e-4)" "unprognostic (3.21e-3)" "unprognostic (2.08e-1)" "unprognostic (9.10e-2)" "unprognostic (1.67e-1)" "unprognostic (2.87e-1)" "unprognostic (1.35e-1)" "unprognostic (1.02e-2)" "unprognostic (1.66e-1)" "unprognostic (8.25e-2)" "unprognostic (3.82e-1)" TGFBR2 "MFS2, TBR-ii, TBRII" ENSG00000163513 "Transforming growth factor beta receptor 2" P37173 3 30606601-30694142 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Apoptosis, Differentiation, Growth regulation" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Cancer-related genes, Craniosynostosis, Disease variant, FDA approved drug targets, Hereditary nonpolyposis colorectal cancer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 446.4;Choroid plexus epithelial cells: 582.0;Lymphatic endothelial cells: 890.2;Microglia: 559.4;Neutrophils: 767.3;pDCs: 462.8;Vascular endothelial cells: 805.9" "Group enriched" "Detected in many" 9 "central nervous system macrophage: 646.8;choroid plexus epithelial cell: 610.3;endothelial cell: 572.4;fibroblast: 371.1;leukocyte: 407.5;pericyte: 296.7;vascular associated smooth muscle cell: 163.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Macrophages, Kidney - Endothelial cells, Pancreas - Endothelial cells, Pituitary gland - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB073537, HPA074821" Enhanced "Plasma membrane" "Secreted to blood" Receptor NA NA 550000 "Cluster 20: Non-specific - DNA binding" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 94 "Plasma membrane" "CAB073537: , HPA074821: " "unprognostic (1.13e-1)" "unprognostic (4.37e-1)" "unprognostic (4.60e-2)" "unprognostic (4.96e-3)" "unprognostic (6.38e-2)" "unprognostic (1.72e-1)" "unprognostic (1.67e-1)" "unprognostic (2.78e-2)" "unprognostic (2.10e-1)" "unprognostic (2.92e-3)" "validated prognostic favorable (2.35e-7)" "validated prognostic favorable (3.61e-4)" "unprognostic (2.97e-1)" "unprognostic (2.96e-1)" "unprognostic (3.33e-2)" "unprognostic (8.78e-2)" "unprognostic (2.21e-1)" "unprognostic (4.04e-2)" "unprognostic (5.62e-2)" "unprognostic (5.82e-3)" "unprognostic (1.32e-3)" "unprognostic (3.90e-2)" "unprognostic (6.15e-2)" "unprognostic (1.91e-1)" "unprognostic (2.00e-1)" "unprognostic (2.75e-3)" "unprognostic (2.56e-1)" "unprognostic (4.84e-2)" "unprognostic (1.94e-2)" "unprognostic (3.62e-2)" "unprognostic (1.88e-1)" TGFBR3 "betaglycan, BGCAN" ENSG00000069702 "Transforming growth factor beta receptor 3" Q03167 1 91680343-91906335 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 526.0;Adrenal cortex cells: 625.7;Breast lactating cells: 826.4;Fibro-adipogenic progenitors: 553.4;Fibroblasts: 598.2;Leydig cells: 407.7;Myosatellite cells: 575.1;Podocytes: 1800.2;Vascular endothelial cells: 412.3" "Cell type enhanced" "Detected in all" "fibroblast: 801.1;leukocyte: 297.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 35.3;MAIT T-cell: 19.5;memory CD4 T-cell: 8.9;memory CD8 T-cell: 19.2;naive CD8 T-cell: 12.8;NK-cell: 16.7" "Group enriched" "Detected in many" 18 "NK-cells: 16.7;T-cells: 35.3" "Cancer enriched" "Detected in many" 6 "Gallbladder cancer: 73.8" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008257, CAB018971" Supported Approved Cytosol "Secreted to blood" Receptor NA NA 11000000 "Cluster 15: NK-cells - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 1 Cytosol "CAB018971: , HPA008257: " "unprognostic (1.35e-3)" "unprognostic (1.35e-1)" "unprognostic (2.25e-3)" "unprognostic (1.70e-1)" "unprognostic (2.12e-1)" "unprognostic (2.96e-3)" "unprognostic (4.46e-2)" "unprognostic (3.39e-1)" "unprognostic (2.85e-3)" "unprognostic (8.88e-3)" "validated prognostic favorable (2.36e-9)" "validated prognostic favorable (9.43e-6)" "unprognostic (1.22e-2)" "unprognostic (8.07e-2)" "unprognostic (4.37e-2)" "unprognostic (6.86e-2)" "unprognostic (1.56e-2)" "unprognostic (2.26e-1)" "potential prognostic favorable (8.87e-4)" "unprognostic (3.95e-2)" "unprognostic (2.16e-2)" "unprognostic (2.60e-1)" "unprognostic (4.82e-2)" "unprognostic (8.58e-2)" "unprognostic (2.63e-1)" "unprognostic (8.96e-2)" "unprognostic (3.83e-1)" "unprognostic (3.05e-1)" "unprognostic (3.30e-1)" "potential prognostic unfavorable (2.52e-4)" "unprognostic (3.30e-1)" TGFBR3L GEMP ENSG00000260001 "Transforming growth factor beta receptor 3 like" H3BV60 19 7914830-7919097 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "pituitary gland: 33.1" "Cell type enriched" "Detected in many" 40 "Gonadotrophs: 948.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adrenal gland - Adrenal medulla cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Pituitary gland - Gonadotropes" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA074356 Enhanced Approved Vesicles NA NA "Cluster 20: Pituitary gland - Hormone signaling" "Cluster 37: Neurons - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" Vesicles "HPA074356: " "unprognostic (1.04e-2)" "unprognostic (3.08e-3)" TGFBRAP1 "TRAP-1, TRAP1, VPS3" ENSG00000135966 "Transforming growth factor beta receptor associated protein 1" Q8WUH2 2 105264391-105329735 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hematopoietic stem cells: 83.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037672, HPA038397" Approved Approved Vesicles NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 22 Vesicles "HPA037672: , HPA038397: " "unprognostic (1.76e-2)" "unprognostic (3.55e-2)" "unprognostic (1.50e-2)" "unprognostic (9.70e-3)" "unprognostic (1.26e-1)" "unprognostic (1.77e-1)" "unprognostic (3.63e-2)" "unprognostic (2.18e-2)" "unprognostic (2.50e-1)" "unprognostic (8.51e-2)" "potential prognostic favorable (9.96e-5)" "unprognostic (1.68e-2)" "unprognostic (2.70e-1)" "unprognostic (1.55e-2)" "unprognostic (4.64e-1)" "unprognostic (7.40e-2)" "unprognostic (4.26e-2)" "unprognostic (1.52e-1)" "unprognostic (1.20e-1)" "unprognostic (2.76e-2)" "unprognostic (4.97e-3)" "unprognostic (7.56e-2)" "unprognostic (1.04e-1)" "unprognostic (9.75e-2)" "unprognostic (1.66e-2)" "unprognostic (1.80e-2)" "unprognostic (7.90e-2)" "unprognostic (1.91e-1)" "unprognostic (2.19e-1)" "unprognostic (5.80e-2)" "unprognostic (3.05e-1)" TGIF1 "HPE4, TGIF" ENSG00000177426 "TGFB induced factor homeobox 1" Q15583 18 3411608-3459978 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Disease variant, Holoprosencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 342.0;Epididymal basal cells: 679.8;Extravillous trophoblasts: 341.5;Migrating cytotrophoblasts: 294.9" "Cell type enhanced" "Detected in many" "ependymal cell: 73.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062160 Supported Nucleoplasm NA Yes "Cluster 43: Non-specific - Transcription & Translation" "Cluster 22: Epididymis - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 103: Non-specific - Basic cellular processes" 24 Nucleoplasm "HPA062160: " "unprognostic (6.31e-2)" "unprognostic (1.39e-1)" "unprognostic (3.47e-3)" "unprognostic (3.47e-3)" "unprognostic (1.21e-1)" "unprognostic (1.96e-1)" "unprognostic (2.78e-2)" "unprognostic (3.02e-2)" "unprognostic (1.52e-1)" "unprognostic (1.53e-1)" "unprognostic (4.88e-3)" "unprognostic (6.80e-2)" "unprognostic (6.09e-2)" "unprognostic (1.65e-1)" "unprognostic (4.93e-2)" "potential prognostic unfavorable (1.55e-5)" "unprognostic (6.92e-3)" "unprognostic (2.84e-2)" "unprognostic (1.72e-1)" "unprognostic (1.42e-2)" "unprognostic (9.42e-2)" "unprognostic (1.83e-3)" "unprognostic (2.55e-1)" "unprognostic (3.58e-2)" "unprognostic (1.45e-1)" "unprognostic (3.64e-2)" "unprognostic (7.14e-2)" "unprognostic (4.55e-2)" "unprognostic (2.41e-1)" "unprognostic (4.61e-1)" "unprognostic (1.36e-1)" TGIF2 ENSG00000118707 "TGFB induced factor homeobox 2" Q9GZN2 20 36573488-36593950 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Choroid plexus epithelial cells: 41.2;Microglia: 78.3" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 85.8;leukocyte: 37.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA053786, HPA064522" Enhanced Nucleoplasm,Centrosome NA NA "Cluster 41: Basophils - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 8: Immune cells - Immune response" "Cluster 62: Non-specific - Plasma proteins" "Cluster 22: Non-specific - Basic cellular functions" 4 Nucleoplasm Centrosome "HPA053786: , HPA064522: " "potential prognostic favorable (7.97e-4)" "unprognostic (1.96e-1)" "unprognostic (9.52e-2)" "unprognostic (3.89e-1)" "unprognostic (5.17e-2)" "unprognostic (1.85e-1)" "unprognostic (4.14e-2)" "unprognostic (1.65e-2)" "unprognostic (1.22e-1)" "unprognostic (1.98e-1)" "unprognostic (2.15e-2)" "unprognostic (1.05e-2)" "unprognostic (8.92e-2)" "unprognostic (4.06e-2)" "unprognostic (2.14e-3)" "unprognostic (4.31e-1)" "unprognostic (1.41e-3)" "unprognostic (8.44e-2)" "potential prognostic favorable (1.87e-4)" "unprognostic (4.00e-1)" "unprognostic (1.37e-1)" "unprognostic (1.36e-2)" "unprognostic (3.93e-3)" "unprognostic (1.67e-1)" "unprognostic (3.25e-2)" "unprognostic (2.45e-3)" "unprognostic (1.37e-1)" "unprognostic (2.05e-1)" "unprognostic (1.75e-1)" "unprognostic (8.31e-3)" "unprognostic (1.59e-2)" TGIF2-RAB5IF TGIF2-C20orf24 ENSG00000259399 "TGIF2-RAB5IF readthrough" 20 36574553-36612384 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cholangiocytes: 15.7;Granulosa cells: 14.6;pDCs: 20.3;Thymocytes: 29.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" HPA076106 Approved Mitochondria NA NA "Cluster 24: Non-specific - Transcription" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" Mitochondria "HPA076106: " "unprognostic (1.45e-1)" "unprognostic (2.76e-1)" "unprognostic (1.24e-3)" "unprognostic (1.31e-1)" "unprognostic (1.22e-1)" "unprognostic (1.53e-2)" "unprognostic (2.09e-1)" "unprognostic (2.52e-3)" "potential prognostic favorable (1.96e-4)" "unprognostic (1.24e-1)" "unprognostic (1.76e-1)" "unprognostic (3.19e-2)" "unprognostic (3.22e-1)" "potential prognostic unfavorable (2.73e-5)" "unprognostic (2.18e-2)" "potential prognostic favorable (7.96e-4)" "unprognostic (5.57e-2)" "unprognostic (3.97e-1)" "unprognostic (1.41e-2)" "unprognostic (5.55e-2)" "unprognostic (1.85e-3)" "unprognostic (1.05e-2)" "unprognostic (8.66e-2)" "unprognostic (4.03e-1)" "unprognostic (1.67e-1)" "unprognostic (3.96e-2)" "unprognostic (6.29e-2)" TGIF2LX ENSG00000153779 "TGFB induced factor homeobox 2 like X-linked" Q8IUE1 X 89921908-89922883 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 86 "testis: 8.6" "Group enriched" "Detected in some" 51 "Early spermatids: 61.5;Late primary spermatocytes: 49.4;Late spermatids: 62.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 3.1;Neuroblastoma: 3.6" "Testis - Early spermatids, Testis - Late spermatids" HPA034543 Supported Approved Nucleoplasm No No "Cluster 6: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 22 Nucleoplasm "HPA034543: " TGIF2LY ENSG00000176679 "TGFB induced factor homeobox 2 like Y-linked" Q8IUE0 Y 3579067-3580041 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 38 "testis: 3.7" "Group enriched" "Detected in some" 44 "Early spermatids: 9.3;Late primary spermatocytes: 20.6;Late spermatids: 20.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" 2 TGM1 "ICR2, LI, LI1, TGASE, TGK" ENSG00000092295 "Transglutaminase 1" P22735 14 24249114-24264432 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Keratinization "Acyltransferase, Transferase" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "esophagus: 697.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 7.8;Epicardial cells: 34.1;Esophageal apical cells: 98.5;Esophageal suprabasal cells: 29.8;Mesothelial cells: 8.3;Ocular epithelial cells: 15.8;Suprabasal keratinocytes: 18.5" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 42.0;Head and Neck Squamous Cell Carcinoma (TCGA): 79.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 41.9" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary gland basal cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB015159, HPA040171, HPA070372" Enhanced Approved "Vesicles,Plasma membrane" NA NA 980000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 60 "Vesicles, Plasma membrane" "CAB015159: , HPA040171: , HPA070372: " "unprognostic (1.61e-1)" "unprognostic (1.25e-1)" "unprognostic (8.59e-2)" "unprognostic (5.71e-2)" "unprognostic (3.93e-3)" "unprognostic (1.23e-1)" "potential prognostic unfavorable (6.18e-5)" "unprognostic (5.12e-2)" "unprognostic (3.14e-2)" "unprognostic (6.07e-2)" "unprognostic (7.10e-2)" "unprognostic (1.14e-1)" "unprognostic (2.08e-2)" "unprognostic (2.48e-2)" "unprognostic (2.48e-1)" "unprognostic (2.21e-2)" "unprognostic (1.31e-2)" "unprognostic (1.08e-1)" "unprognostic (4.23e-1)" "unprognostic (1.77e-1)" "unprognostic (1.45e-1)" "unprognostic (8.25e-2)" "unprognostic (1.20e-2)" "unprognostic (1.16e-1)" TGM2 TGC ENSG00000198959 "Transglutaminase 2" P21980 20 38127385-38166578 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Acyltransferase, Hydrolase, Protease, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 775.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 399.8;Decidual stromal cells: 1215.0;Endometrial secretory cells: 221.7;Endometrial stromal cells: 343.4;Epididymal efferent duct absorptive cells: 825.2;Lymphatic endothelial cells: 298.5;Migrating cytotrophoblasts: 293.4;Syncytiotrophoblasts: 453.5;Vascular endothelial cells: 243.8;Vascular smooth muscle cells: 285.8" "Cell type enriched" "Detected in some" 4 "endothelial cell: 270.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "pancreatic cancer: 424.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002598, HPA021019, HPA029518" Enhanced Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" Enzyme Yes No 970000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 25 Cytosol "Plasma membrane" "CAB002598: , HPA021019: , HPA029518: " "unprognostic (6.82e-2)" "unprognostic (2.33e-1)" "unprognostic (5.50e-2)" "unprognostic (6.11e-3)" "unprognostic (8.06e-2)" "unprognostic (1.10e-1)" "unprognostic (1.23e-3)" "potential prognostic unfavorable (1.34e-5)" "unprognostic (2.27e-3)" "unprognostic (2.64e-1)" "unprognostic (1.80e-2)" "unprognostic (1.00e-1)" "unprognostic (5.00e-2)" "unprognostic (2.13e-1)" "unprognostic (2.50e-1)" "unprognostic (1.21e-1)" "unprognostic (1.20e-1)" "unprognostic (1.55e-3)" "unprognostic (3.78e-3)" "unprognostic (9.74e-3)" "potential prognostic unfavorable (3.77e-4)" "unprognostic (3.06e-3)" "potential prognostic unfavorable (6.14e-5)" "unprognostic (7.61e-2)" "unprognostic (4.89e-2)" "unprognostic (1.41e-2)" "unprognostic (2.35e-1)" "unprognostic (4.98e-3)" "unprognostic (2.75e-3)" "unprognostic (2.77e-1)" "unprognostic (3.45e-1)" TGM3 TGE ENSG00000125780 "Transglutaminase 3" Q08188 20 2296001-2341079 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Keratinization "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "esophagus: 1777.7" "Cell type enriched" "Detected in some" 18 "Esophageal apical cells: 848.4" "Cell type enriched" "Detected in some" 4 "ependymal cell: 20.2" "Cancer enriched" "Detected in many" 11 "Head and Neck Squamous Cell Carcinoma (TCGA): 106.8" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 295 "neutrophil: 30.4" "Lineage enriched" "Detected in single" 304 "granulocytes: 30.4" "Cancer enriched" "Detected in some" 19 "Rhabdoid: 124.8" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA004728 Approved NA NA 15000000 "Cluster 4: Neutrophils - Degranulation" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 5: Rhabdoid - Unknown function" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 32 "HPA004728: " "unprognostic (2.41e-1)" "unprognostic (1.38e-1)" "unprognostic (5.50e-2)" "unprognostic (8.32e-2)" "unprognostic (1.31e-1)" "unprognostic (3.97e-3)" "unprognostic (3.55e-2)" "unprognostic (1.95e-1)" "unprognostic (1.50e-1)" "unprognostic (2.10e-1)" "unprognostic (2.43e-1)" TGM4 TGP ENSG00000163810 "Transglutaminase 4" P49221 3 44874608-44914990 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 341 "prostate: 767.7" "Group enriched" "Detected in some" 4 "Late spermatids: 11.8;Prostatic glandular cells: 10.3" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 517 "Prostate Adenocarcinoma (TCGA): 91.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "CAB033571, HPA073290" Enhanced NA NA "Cluster 38: Non-specific - Basic cellular processes" "Cluster 34: Testis cancer - Unknown function" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 2 "CAB033571: , HPA073290: " "unprognostic (8.52e-2)" TGM5 "TGMX, TGX" ENSG00000104055 "Transglutaminase 5" O43548 15 43232590-43266928 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 11.4;skin 1: 37.4" "Cell type enriched" "Detected in some" 4 "Esophageal apical cells: 133.8" "Group enriched" "Detected in some" 5 "astrocyte: 4.3;Bergmann glia: 1.5" "Cancer enhanced" "Detected in some" "Head and Neck Squamous Cell Carcinoma (TCGA): 4.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 6.0;Leukemia: 4.1" "Region enriched" "Detected in single" 12 "cerebellum: 2.6" "Low region specificity" "Detected in all" NA NA 58000 "Cluster 58: Skin - Keratinization" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 6 "unprognostic (1.63e-2)" "unprognostic (1.18e-2)" "unprognostic (3.46e-1)" "unprognostic (5.49e-2)" "unprognostic (8.51e-2)" "potential prognostic unfavorable (1.50e-4)" "unprognostic (3.15e-1)" "unprognostic (5.00e-3)" "unprognostic (5.54e-2)" TGM6 "dJ734P14.3, SCA35, TGM3L, TGY" ENSG00000166948 "Transglutaminase 6" O95932 20 2380901-2432753 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Acyltransferase, Transferase" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 5 "Tuft cells: 11.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Skin - Inner root sheath cells" "Not detected" "Not detected" "Region enriched" "Detected in single" 20 "cerebellum: 2.0" HPA059196 Uncertain NA NA "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" "HPA059196: " TGM7 TGMZ ENSG00000159495 "Transglutaminase 7" Q96PF1 15 43276271-43302255 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.5" "Cell type enhanced" "Detected in some" "Early spermatids: 88.8;Esophageal apical cells: 42.9;Late primary spermatocytes: 12.0;Late spermatids: 23.5;Oocytes: 13.8;Suprabasal keratinocytes: 7.1" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 12 "Uterine Corpus Endometrial Carcinoma (TCGA): 2.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Sebaceous gland cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 39: Testis - Nuclear processes" "Cluster 15: Kidney cancer - Membrane components" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 15 "unprognostic (1.46e-1)" TGOLN2 "TGN38, TGN46, TGN48, TGN51, TTGN2" ENSG00000152291 "Trans-golgi network protein 2" O43493 2 85318027-85328251 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011489, HPA012609, HPA012723" Enhanced Supported "Nucleoplasm,Golgi apparatus" NA NA 25000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 105 "Golgi apparatus" Nucleoplasm "CAB011489: , HPA012609: , HPA012723: " "unprognostic (3.35e-2)" "unprognostic (5.28e-3)" "unprognostic (8.30e-3)" "unprognostic (1.43e-2)" "unprognostic (5.35e-2)" "unprognostic (1.30e-1)" "unprognostic (1.51e-1)" "unprognostic (6.17e-2)" "unprognostic (4.40e-1)" "unprognostic (7.46e-2)" "potential prognostic favorable (5.46e-6)" "unprognostic (2.21e-2)" "unprognostic (2.81e-1)" "unprognostic (2.87e-2)" "unprognostic (2.12e-1)" "unprognostic (9.47e-2)" "unprognostic (2.97e-1)" "unprognostic (6.63e-2)" "unprognostic (5.75e-2)" "unprognostic (5.35e-3)" "unprognostic (1.34e-2)" "unprognostic (7.93e-2)" "unprognostic (3.17e-2)" "unprognostic (8.01e-2)" "unprognostic (1.31e-1)" "unprognostic (2.27e-1)" "unprognostic (2.71e-1)" "unprognostic (1.75e-1)" "unprognostic (1.14e-1)" "unprognostic (9.11e-2)" "unprognostic (3.69e-1)" TGS1 "NCOA6IP, PIMT" ENSG00000137574 "Trimethylguanosine synthase 1" Q96RS0 8 55773446-55826445 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025024, HPA029824" Supported Supported Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 2: Neurons - Nucleosome" "Cluster 40: Non-specific - Unknown function" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 33 Cytosol "HPA025024: , HPA029824: " "unprognostic (5.91e-3)" "unprognostic (3.04e-2)" "unprognostic (2.31e-1)" "unprognostic (4.79e-2)" "unprognostic (2.51e-1)" "unprognostic (3.24e-2)" "unprognostic (3.12e-1)" "unprognostic (3.34e-3)" "unprognostic (2.74e-1)" "unprognostic (7.36e-2)" "potential prognostic favorable (1.53e-4)" "unprognostic (6.48e-2)" "unprognostic (2.54e-1)" "unprognostic (2.58e-2)" "unprognostic (3.79e-2)" "unprognostic (1.41e-2)" "unprognostic (6.25e-2)" "unprognostic (2.18e-1)" "unprognostic (9.92e-3)" "unprognostic (1.02e-1)" "unprognostic (9.20e-2)" "unprognostic (5.46e-2)" "unprognostic (8.58e-3)" "unprognostic (1.28e-1)" "unprognostic (4.14e-2)" "unprognostic (2.10e-1)" "unprognostic (5.50e-1)" "unprognostic (7.64e-2)" "unprognostic (9.23e-2)" "unprognostic (2.92e-1)" "unprognostic (1.38e-1)" TH DYT5b ENSG00000180176 "Tyrosine hydroxylase" P07101 11 2163929-2171815 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Catecholamine biosynthesis, Neurotransmitter biosynthesis" "Monooxygenase, Oxidoreductase" "Disease variant, Dystonia, FDA approved drug targets, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 50 "adrenal gland: 185.6;brain: 129.8" "Cell type enriched" "Detected in some" 9 "Adrenal medulla cells: 414.8" "Cell type enhanced" "Detected in some" "eccentric medium spiny neuron: 6.4;medium spiny neuron: 5.5" "Group enriched" "Detected in some" 4 "Bladder Urothelial Carcinoma (TCGA): 8.5;Head and Neck Squamous Cell Carcinoma (TCGA): 2.2" "Group enriched" "Detected in many" 5 "midbrain: 416.9;pons: 573.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "Brain cancer: 28.9;Neuroblastoma: 62.3" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Testis - Spermatogonia" "Region enhanced" "Detected in many" "olfactory bulb: 178.8" "Region enriched" "Detected in many" 20 "midbrain: 999.2" "CAB002522, HPA013768, HPA014010, HPA061003, CAB072340" Enhanced Supported Approved Cytosol NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 1 Cytosol "CAB002522: , CAB072340: , HPA013768: , HPA014010: , HPA061003: " "unprognostic (1.68e-1)" "unprognostic (3.76e-2)" "unprognostic (1.22e-2)" "unprognostic (9.59e-2)" "unprognostic (4.74e-1)" "unprognostic (2.10e-1)" THADA "ARMC13, FLJ21877, GITA, KIAA1767, Trm732" ENSG00000115970 "THADA armadillo repeat containing" Q6YHU6 2 43230851-43596038 "Disease related genes, Predicted intracellular proteins" "tRNA processing" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 17.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035191, HPA035192" Uncertain Approved Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 3: Choroid plexus - Cilium" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 7: Non-specific - Transcription" 24 Cytosol "HPA035191: , HPA035192: " "unprognostic (3.38e-2)" "unprognostic (2.95e-2)" "unprognostic (5.62e-2)" "unprognostic (1.20e-1)" "unprognostic (1.41e-1)" "unprognostic (4.17e-3)" "unprognostic (1.85e-1)" "unprognostic (3.38e-1)" "unprognostic (2.21e-2)" "unprognostic (2.10e-1)" "unprognostic (2.08e-2)" "unprognostic (3.55e-1)" "unprognostic (2.77e-1)" "potential prognostic unfavorable (5.11e-5)" "unprognostic (5.06e-2)" "unprognostic (3.56e-1)" "unprognostic (9.46e-3)" "unprognostic (3.28e-3)" "unprognostic (1.99e-1)" "unprognostic (1.47e-1)" "unprognostic (7.96e-2)" "unprognostic (5.57e-3)" "potential prognostic unfavorable (4.32e-4)" "unprognostic (3.26e-1)" "unprognostic (7.05e-2)" "unprognostic (2.92e-3)" "unprognostic (1.77e-1)" "unprognostic (3.80e-2)" "unprognostic (4.32e-2)" "unprognostic (2.25e-2)" "unprognostic (2.02e-1)" THAP1 "4833431A01Rik, DYT6, FLJ10477" ENSG00000131931 "THAP domain containing 1" Q9NVV9 8 42836674-42843325 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" DNA-binding "Disease variant, Dystonia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 48.2;Oocytes: 50.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071310 Supported Nucleoplasm No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 9: T-cells - Adaptive immunity: Regulation" 93 Nucleoplasm "HPA071310: " "unprognostic (2.69e-1)" "unprognostic (1.31e-3)" "unprognostic (1.28e-1)" "unprognostic (1.05e-3)" "unprognostic (5.58e-2)" "unprognostic (1.30e-1)" "unprognostic (4.04e-2)" "unprognostic (1.09e-1)" "unprognostic (5.43e-2)" "unprognostic (4.78e-3)" "potential prognostic favorable (2.22e-8)" "unprognostic (7.61e-3)" "unprognostic (5.91e-2)" "unprognostic (6.67e-2)" "unprognostic (1.60e-1)" "unprognostic (1.81e-1)" "unprognostic (1.97e-1)" "unprognostic (7.40e-2)" "unprognostic (3.01e-2)" "unprognostic (5.35e-2)" "unprognostic (2.68e-3)" "unprognostic (2.97e-2)" "unprognostic (2.06e-2)" "unprognostic (5.23e-2)" "unprognostic (1.02e-1)" "unprognostic (1.77e-1)" "unprognostic (1.89e-2)" "unprognostic (1.46e-1)" "unprognostic (4.23e-1)" "unprognostic (2.22e-1)" "unprognostic (1.18e-2)" THAP10 ENSG00000129028 "THAP domain containing 10" Q9P2Z0 15 70881342-70892433 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Epicardial cells: 29.6;Late primary spermatocytes: 27.4;Oocytes: 32.2;Parietal cells: 46.0;Retinal bipolar cells: 15.4" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 15.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "non-classical monocyte: 4.2" "Lineage enriched" "Detected in single" 7 "monocytes: 4.2" "Low cancer specificity" "Detected in many" "Stomach - Parietal cells, Testis - Early spermatids" "HPA041416, HPA073220" Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 16: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 21 Nucleoplasm "Golgi apparatus, Cytosol" "HPA041416: , HPA073220: " "unprognostic (1.37e-2)" "unprognostic (4.08e-2)" "unprognostic (6.42e-2)" "unprognostic (1.03e-1)" "unprognostic (3.87e-2)" "unprognostic (5.62e-2)" "unprognostic (1.26e-1)" "unprognostic (1.14e-1)" "unprognostic (3.52e-2)" "unprognostic (2.51e-2)" "potential prognostic favorable (1.03e-8)" "unprognostic (1.69e-2)" "unprognostic (2.71e-3)" "unprognostic (2.27e-1)" "unprognostic (1.89e-1)" "unprognostic (1.51e-3)" "unprognostic (1.43e-1)" "unprognostic (4.19e-2)" "unprognostic (2.43e-1)" "unprognostic (1.93e-2)" "unprognostic (1.74e-1)" "unprognostic (1.10e-1)" "unprognostic (3.58e-1)" "unprognostic (1.76e-3)" "unprognostic (1.50e-2)" "unprognostic (2.94e-2)" "unprognostic (1.73e-2)" "unprognostic (1.38e-1)" "unprognostic (2.58e-1)" "unprognostic (6.31e-2)" "unprognostic (1.01e-2)" THAP11 "CTG-B43a, CTG-B45d, HRIHFB2206, RONIN" ENSG00000168286 "THAP domain containing 11" Q96EK4 16 67842320-67844195 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Disease variant, Epilepsy, Intellectual disability, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Platelets: 53.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041434, HPA042189, HPA072537" Supported Supported Nucleoplasm,Cytosol NA No "Cluster 33: Non-specific - ATP binding" "Cluster 24: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 97: Non-specific - Cellular respiration" 16 Nucleoplasm Cytosol "HPA041434: , HPA042189: , HPA072537: " "unprognostic (2.29e-1)" "unprognostic (2.46e-1)" "unprognostic (1.73e-1)" "unprognostic (2.30e-2)" "unprognostic (1.27e-1)" "unprognostic (7.73e-2)" "unprognostic (2.96e-3)" "unprognostic (3.77e-3)" "unprognostic (1.16e-1)" "unprognostic (6.76e-2)" "potential prognostic favorable (1.10e-4)" "unprognostic (7.50e-2)" "unprognostic (8.37e-2)" "potential prognostic unfavorable (7.60e-4)" "unprognostic (3.61e-3)" "unprognostic (5.42e-2)" "unprognostic (2.36e-2)" "unprognostic (1.17e-1)" "unprognostic (8.35e-3)" "unprognostic (1.90e-1)" "unprognostic (2.49e-1)" "unprognostic (1.13e-1)" "unprognostic (9.45e-2)" "unprognostic (2.43e-1)" "unprognostic (6.53e-2)" "unprognostic (1.67e-1)" "unprognostic (6.77e-2)" "unprognostic (3.25e-1)" "unprognostic (6.80e-2)" "unprognostic (5.09e-3)" "unprognostic (5.93e-2)" THAP12 "DAP4, P52rIPK, PRKRIR, THAP0" ENSG00000137492 "THAP domain containing 12" O43422 11 76349898-76381132 "Plasma proteins, Predicted membrane proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008758, HPA077077" Approved Approved Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 24: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 45 Cytosol "HPA008758: , HPA077077: " "unprognostic (5.98e-2)" "unprognostic (2.77e-1)" "unprognostic (4.42e-2)" "unprognostic (6.91e-2)" "unprognostic (1.86e-2)" "unprognostic (5.45e-3)" "unprognostic (7.16e-3)" "unprognostic (2.05e-1)" "unprognostic (9.59e-2)" "potential prognostic favorable (3.16e-4)" "unprognostic (1.51e-1)" "unprognostic (8.91e-2)" "unprognostic (1.36e-2)" "unprognostic (1.39e-1)" "unprognostic (1.35e-2)" "unprognostic (2.61e-1)" "unprognostic (2.47e-1)" "unprognostic (2.37e-1)" "unprognostic (3.23e-2)" "unprognostic (7.81e-2)" "unprognostic (4.19e-2)" "unprognostic (4.90e-2)" "potential prognostic favorable (7.20e-4)" "unprognostic (2.75e-2)" "unprognostic (5.95e-2)" "unprognostic (3.65e-1)" "unprognostic (1.78e-1)" "unprognostic (2.09e-2)" "unprognostic (3.89e-1)" THAP2 DKFZP564I0422 ENSG00000173451 "THAP domain containing 2" Q9H0W7 12 71664301-71680644 "Plasma proteins, Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 93.6;Late spermatids: 83.5;Mast cells: 50.3;monocytes: 108.0;Vascular smooth muscle cells: 53.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039790 Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 103: Non-specific - Basic cellular processes" "Golgi apparatus" Nucleoplasm "HPA039790: " "unprognostic (4.99e-2)" "unprognostic (1.82e-2)" "unprognostic (2.61e-2)" "unprognostic (8.60e-2)" "unprognostic (1.49e-3)" "unprognostic (4.41e-2)" "unprognostic (1.10e-2)" "unprognostic (6.17e-2)" "unprognostic (3.72e-2)" "unprognostic (9.96e-3)" "unprognostic (7.12e-2)" "unprognostic (1.91e-1)" "unprognostic (4.44e-2)" "potential prognostic unfavorable (1.34e-5)" "unprognostic (6.56e-3)" "unprognostic (1.28e-2)" "unprognostic (1.27e-1)" "unprognostic (2.79e-1)" "unprognostic (2.71e-1)" "unprognostic (1.74e-1)" "unprognostic (9.42e-2)" "unprognostic (3.61e-3)" "unprognostic (3.23e-2)" "unprognostic (8.42e-2)" "unprognostic (1.19e-1)" "unprognostic (1.63e-2)" "unprognostic (1.82e-2)" "unprognostic (1.49e-1)" "unprognostic (8.43e-2)" "unprognostic (6.06e-2)" "unprognostic (3.88e-1)" THAP3 ENSG00000041988 "THAP domain containing 3" Q8WTV1 1 6624868-6635586 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067114 Approved Approved Nucleoplasm,Nucleoli,Mitochondria No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 70: Non-specific - Protein processing" "Cluster 6: Non-specific - Immune response" "Cluster 35: RS4;11 - Unknown function" "Cluster 110: Mural cells - ECM organization" 18 Nucleoplasm "Nucleoli, Mitochondria" "HPA067114: " "unprognostic (3.52e-1)" "unprognostic (2.03e-1)" "unprognostic (4.49e-2)" "unprognostic (7.33e-2)" "unprognostic (3.80e-2)" "unprognostic (6.19e-3)" "unprognostic (2.53e-1)" "unprognostic (1.00e-2)" "unprognostic (5.38e-2)" "unprognostic (1.26e-1)" "unprognostic (1.06e-1)" "unprognostic (2.64e-3)" "unprognostic (6.23e-3)" "potential prognostic unfavorable (7.90e-5)" "unprognostic (1.38e-3)" "unprognostic (1.85e-2)" "unprognostic (1.14e-1)" "unprognostic (1.81e-2)" "unprognostic (1.97e-1)" "unprognostic (1.40e-1)" "unprognostic (6.72e-2)" "unprognostic (5.16e-3)" "unprognostic (6.10e-2)" "unprognostic (1.74e-1)" "unprognostic (4.18e-2)" "unprognostic (4.50e-3)" "unprognostic (3.87e-1)" "unprognostic (1.37e-1)" "unprognostic (3.69e-2)" "unprognostic (2.47e-1)" "unprognostic (1.45e-1)" THAP4 "CGI-36, Nb(III)" ENSG00000176946 "THAP domain containing 4" Q8WY91 2 241584405-241637158 "Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "DNA-binding, Isomerase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044982 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 39 "Nucleoplasm, Cytosol" "HPA044982: " "unprognostic (1.63e-1)" "unprognostic (1.06e-1)" "unprognostic (1.55e-1)" "unprognostic (2.12e-1)" "unprognostic (1.25e-1)" "unprognostic (2.24e-1)" "unprognostic (5.75e-3)" "unprognostic (1.15e-1)" "unprognostic (2.34e-2)" "unprognostic (1.38e-1)" "unprognostic (1.12e-3)" "unprognostic (4.71e-3)" "potential prognostic favorable (2.07e-5)" "unprognostic (5.66e-3)" "potential prognostic unfavorable (5.66e-5)" "unprognostic (2.01e-2)" "unprognostic (6.67e-2)" "unprognostic (1.51e-1)" "unprognostic (4.77e-2)" "unprognostic (2.18e-1)" "unprognostic (7.35e-2)" "unprognostic (1.08e-1)" "unprognostic (1.24e-1)" "unprognostic (4.46e-2)" "unprognostic (3.25e-1)" "unprognostic (2.67e-1)" "unprognostic (1.40e-1)" "unprognostic (1.27e-1)" "unprognostic (5.15e-2)" "unprognostic (2.22e-1)" "unprognostic (1.51e-1)" THAP5 DKFZp313O1132 ENSG00000177683 "THAP domain containing 5" Q7Z6K1 7 108554543-108569750 "Predicted intracellular proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 61.8;Late spermatids: 114.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "HPA043170, HPA051488" Approved Supported Nucleoplasm NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" Nucleoplasm "HPA043170: , HPA051488: " "unprognostic (8.29e-2)" "unprognostic (3.21e-2)" "unprognostic (6.03e-3)" "unprognostic (1.50e-2)" "unprognostic (2.00e-1)" "unprognostic (4.71e-2)" "unprognostic (2.85e-2)" "unprognostic (5.54e-2)" "unprognostic (5.78e-2)" "unprognostic (2.80e-2)" "potential prognostic favorable (6.44e-8)" "unprognostic (6.93e-3)" "unprognostic (8.77e-2)" "unprognostic (2.86e-2)" "unprognostic (1.52e-1)" "unprognostic (2.55e-2)" "unprognostic (1.01e-1)" "unprognostic (1.54e-1)" "unprognostic (4.31e-1)" "unprognostic (1.37e-1)" "unprognostic (2.51e-2)" "unprognostic (8.31e-2)" "unprognostic (2.65e-2)" "unprognostic (1.48e-1)" "unprognostic (8.84e-2)" "unprognostic (2.45e-2)" "unprognostic (1.53e-2)" "unprognostic (2.77e-1)" "unprognostic (3.51e-2)" "unprognostic (6.33e-3)" "unprognostic (2.65e-2)" THAP6 MGC30052 ENSG00000174796 "THAP domain containing 6" Q8TBB0 4 75513946-75550473 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 126.7;Early spermatids: 175.1;Late primary spermatocytes: 105.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" HPA035767 Uncertain Approved Nucleoplasm,Centrosome NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 40: Non-specific - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 15 Centrosome Nucleoplasm "HPA035767: " "unprognostic (5.78e-2)" "unprognostic (1.77e-3)" "unprognostic (1.50e-1)" "unprognostic (7.16e-2)" "unprognostic (1.47e-2)" "unprognostic (1.68e-1)" "unprognostic (1.80e-1)" "unprognostic (6.57e-2)" "unprognostic (2.36e-1)" "potential prognostic unfavorable (2.50e-4)" "unprognostic (3.08e-2)" "potential prognostic favorable (8.65e-4)" "unprognostic (8.55e-3)" "unprognostic (1.50e-3)" "unprognostic (1.34e-3)" "unprognostic (5.43e-2)" "unprognostic (2.28e-1)" "unprognostic (4.37e-1)" "potential prognostic favorable (3.20e-5)" "unprognostic (3.43e-2)" "unprognostic (1.89e-1)" "unprognostic (3.17e-2)" "potential prognostic unfavorable (8.92e-4)" "unprognostic (1.84e-2)" "potential prognostic favorable (1.03e-4)" "unprognostic (4.07e-1)" "unprognostic (1.07e-1)" "unprognostic (3.38e-1)" "unprognostic (1.21e-1)" "unprognostic (5.82e-2)" "unprognostic (1.89e-1)" THAP7 MGC10963 ENSG00000184436 "THAP domain containing 7" Q9BT49 22 20999104-21002196 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 206.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003083 Approved Supported "Nucleoplasm,Nuclear membrane,Vesicles" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 66: Non-specific - Mitochondria" "Cluster 3: Early primary spermatocytes - Early meiosis" 55 Nucleoplasm "Nuclear membrane, Vesicles" "HPA003083: " "unprognostic (7.33e-2)" "unprognostic (2.94e-1)" "unprognostic (1.54e-1)" "unprognostic (2.73e-1)" "unprognostic (7.17e-2)" "unprognostic (3.49e-2)" "unprognostic (4.67e-1)" "unprognostic (5.07e-2)" "unprognostic (3.40e-2)" "unprognostic (9.80e-2)" "potential prognostic unfavorable (9.45e-4)" "unprognostic (2.52e-1)" "unprognostic (2.09e-2)" "unprognostic (8.74e-3)" "unprognostic (1.56e-1)" "unprognostic (1.05e-1)" "unprognostic (3.44e-1)" "unprognostic (2.12e-2)" "unprognostic (1.59e-1)" "unprognostic (8.47e-3)" "unprognostic (1.89e-1)" "potential prognostic favorable (9.95e-4)" "unprognostic (2.24e-1)" "unprognostic (7.61e-3)" "unprognostic (6.47e-2)" "unprognostic (1.74e-3)" "unprognostic (1.88e-1)" "unprognostic (4.95e-2)" "unprognostic (1.45e-1)" "unprognostic (1.41e-2)" "unprognostic (8.77e-2)" THAP8 FLJ32891 ENSG00000161277 "THAP domain containing 8" Q8NA92 19 36034984-36054739 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 24.5;Early primary spermatocytes: 25.6;Hofbauer cells: 23.2;Oocytes: 46.1;Undifferentiated spermatogonia: 20.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "HPA064056, HPA070139" Approved Enhanced Nucleoplasm NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 67: Testis - Mixed function" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 4: Non-specific - Transcription" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 6 Nucleoplasm "HPA064056: , HPA070139: " "unprognostic (1.54e-1)" "unprognostic (9.25e-2)" "unprognostic (1.17e-1)" "unprognostic (1.00e-1)" "unprognostic (5.02e-2)" "unprognostic (2.23e-1)" "unprognostic (2.31e-1)" "unprognostic (1.18e-1)" "unprognostic (7.21e-2)" "unprognostic (4.08e-1)" "unprognostic (1.11e-1)" "unprognostic (2.96e-2)" "unprognostic (1.31e-2)" "potential prognostic unfavorable (4.27e-7)" "unprognostic (4.43e-1)" "unprognostic (1.34e-1)" "unprognostic (9.30e-2)" "potential prognostic favorable (3.13e-4)" "unprognostic (3.19e-1)" "unprognostic (2.25e-1)" "unprognostic (2.16e-1)" "unprognostic (8.07e-3)" "unprognostic (1.24e-1)" "unprognostic (1.39e-1)" "unprognostic (1.23e-1)" "unprognostic (1.03e-1)" "unprognostic (1.17e-1)" "unprognostic (7.49e-2)" "unprognostic (4.92e-2)" "unprognostic (3.28e-2)" "unprognostic (4.58e-3)" THAP9 FLJ34093 ENSG00000168152 "THAP domain containing 9" Q9H5L6 4 82900684-82919969 "Predicted intracellular proteins, Transcription factors" "DNA integration, DNA recombination" "DNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 65.5;Late spermatids: 81.2;Neutrophils: 69.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "HPA037420, HPA037421" Uncertain Approved Mitochondria No No "Cluster 14: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 1 Mitochondria "HPA037420: , HPA037421: " "unprognostic (5.03e-2)" "unprognostic (2.19e-3)" "unprognostic (3.99e-1)" "unprognostic (1.79e-2)" "unprognostic (2.46e-2)" "unprognostic (2.48e-2)" "unprognostic (3.62e-1)" "unprognostic (1.35e-1)" "unprognostic (2.06e-2)" "unprognostic (1.12e-1)" "validated prognostic favorable (3.53e-7)" "validated prognostic favorable (1.43e-4)" "unprognostic (1.90e-2)" "unprognostic (1.87e-1)" "unprognostic (9.78e-3)" "unprognostic (1.28e-1)" "unprognostic (5.62e-2)" "unprognostic (8.77e-2)" "unprognostic (2.10e-2)" "unprognostic (1.18e-1)" "unprognostic (2.62e-1)" "unprognostic (3.47e-2)" "unprognostic (9.62e-2)" "unprognostic (2.32e-2)" "unprognostic (4.05e-3)" "unprognostic (1.04e-1)" "unprognostic (6.60e-2)" "unprognostic (1.14e-1)" "unprognostic (1.32e-1)" "unprognostic (2.03e-2)" "unprognostic (1.53e-1)" THBD "BDCA-3, CD141, THRM" ENSG00000178726 Thrombomodulin P07204 20 23045633-23049672 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" "Blood coagulation, Hemostasis" Receptor "Disease variant, Hemolytic uremic syndrome, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 90.5;Esophageal suprabasal cells: 69.7;Hepatic stellate cells: 64.5;Leydig cells: 129.0;Lymphatic endothelial cells: 246.0;Macrophages: 103.8;monocytes: 278.0;Ocular epithelial cells: 67.8;Peritubular myoid cells: 269.2;Suprabasal keratinocytes: 88.7;Vascular endothelial cells: 246.3" "Group enriched" "Detected in some" 6 "endothelial cell: 27.8;vascular associated smooth muscle cell: 11.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 24.6" "Group enriched" "Detected in many" 7 "dendritic cells: 10.9;granulocytes: 24.6;monocytes: 9.0" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 97.2" "Breast - Endothelial cells, Heart muscle - Endothelial cells, Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002425, HPA002982" Supported Approved Nucleoplasm,Cytosol NA NA 390000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 20 "Nucleoplasm, Cytosol" "CAB002425: , HPA002982: " "unprognostic (1.19e-1)" "unprognostic (1.57e-1)" "unprognostic (2.06e-3)" "unprognostic (1.74e-3)" "unprognostic (1.54e-1)" "unprognostic (1.50e-1)" "unprognostic (4.74e-3)" "unprognostic (2.53e-2)" "unprognostic (1.57e-1)" "unprognostic (2.78e-2)" "potential prognostic favorable (3.82e-4)" "unprognostic (3.66e-2)" "unprognostic (7.57e-2)" "unprognostic (4.68e-3)" "unprognostic (1.30e-3)" "unprognostic (2.30e-1)" "unprognostic (6.41e-3)" "unprognostic (2.96e-2)" "unprognostic (1.70e-2)" "unprognostic (1.38e-2)" "unprognostic (1.82e-1)" "unprognostic (1.42e-1)" "unprognostic (1.19e-2)" "unprognostic (2.27e-2)" "unprognostic (1.64e-2)" "unprognostic (1.56e-2)" "unprognostic (2.20e-1)" "unprognostic (1.17e-2)" "unprognostic (1.48e-1)" "unprognostic (6.12e-3)" "unprognostic (4.25e-1)" THBS1 "THBS, THBS-1, TSP, TSP-1, TSP1" ENSG00000137801 "Thrombospondin 1" P07996 15 39581079-39599466 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Angiogenesis, Apoptosis, Cell adhesion, Inflammatory response, Unfolded protein response" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 339.5;Hepatic stellate cells: 316.3;Macrophages: 365.7;monocytes: 2455.1;Platelets: 634.2;Salivary acinar cells: 320.0;Salivary ionocytes: 560.6;Salivary myoepithelial cells: 594.7;Smooth muscle cells: 472.1;Vascular smooth muscle cells: 386.4" "Group enriched" "Detected in many" 7 "fibroblast: 84.0;vascular associated smooth muscle cell: 68.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 15.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Neutrophils, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 27.1" "CAB033678, HPA042942" Approved Approved "Endoplasmic reticulum,Plasma membrane" "Secreted to extracellular matrix" "Cell adhesion" NA NA 5200000000 "Cluster 7: Non-specific - Innate immune response" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 44: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 28 "Endoplasmic reticulum, Plasma membrane" "CAB033678: , HPA042942: " "unprognostic (2.91e-1)" "unprognostic (4.05e-2)" "unprognostic (7.46e-2)" "unprognostic (2.17e-2)" "unprognostic (4.92e-2)" "unprognostic (1.09e-1)" "unprognostic (2.39e-2)" "unprognostic (2.48e-3)" "unprognostic (1.17e-3)" "unprognostic (2.74e-1)" "validated prognostic favorable (1.67e-4)" "validated prognostic favorable (2.49e-4)" "unprognostic (2.31e-2)" "unprognostic (3.49e-1)" "unprognostic (1.84e-1)" "unprognostic (6.73e-2)" "unprognostic (2.05e-3)" "unprognostic (8.19e-3)" "unprognostic (1.25e-1)" "unprognostic (1.15e-1)" "unprognostic (1.25e-3)" "unprognostic (2.97e-2)" "unprognostic (1.11e-1)" "unprognostic (9.65e-2)" "unprognostic (3.27e-1)" "potential prognostic favorable (5.32e-4)" "unprognostic (1.30e-1)" "potential prognostic unfavorable (1.40e-4)" "unprognostic (1.50e-1)" "unprognostic (8.89e-3)" "unprognostic (7.25e-2)" THBS2 TSP2 ENSG00000186340 "Thrombospondin 2" P35442 6 169215780-169254050 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" Heparin-binding "Cancer-related genes, Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 160.2" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 57.4;Endometrial stromal cells: 115.2;Epicardial cells: 197.9;Fibro-adipogenic progenitors: 67.1;Fibroblasts: 252.7;Hepatic stellate cells: 303.4;Oligodendrocyte progenitor cells: 62.0;Oligodendrocytes: 58.6;Somatotrophs: 443.8" "Group enriched" "Detected in many" 5 "astrocyte: 68.5;committed oligodendrocyte precursor: 73.0;fibroblast: 132.4;oligodendrocyte: 49.7;oligodendrocyte precursor cell: 60.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 156.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017716, HPA066883, HPA069350" Approved Approved "Plasma membrane,Centrosome,Cytosol" "Secreted to extracellular matrix" "Cell adhesion" NA NA 120000000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 1 "Plasma membrane" "Centrosome, Cytosol" "CAB017716: , HPA066883: , HPA069350: " "unprognostic (3.31e-1)" "unprognostic (3.19e-2)" "unprognostic (2.30e-1)" "unprognostic (5.07e-2)" "unprognostic (6.06e-2)" "unprognostic (1.12e-1)" "unprognostic (3.81e-2)" "unprognostic (3.98e-2)" "unprognostic (2.72e-1)" "unprognostic (2.69e-1)" "unprognostic (2.52e-1)" "unprognostic (7.82e-2)" "unprognostic (5.49e-2)" "unprognostic (1.63e-1)" "unprognostic (8.00e-2)" "unprognostic (7.35e-2)" "unprognostic (5.32e-3)" "unprognostic (5.95e-2)" "unprognostic (1.86e-1)" "validated prognostic unfavorable (1.93e-4)" "validated prognostic unfavorable (3.94e-5)" "unprognostic (3.97e-2)" "unprognostic (2.82e-1)" "unprognostic (1.54e-1)" "unprognostic (3.13e-1)" "potential prognostic favorable (7.34e-4)" "unprognostic (1.84e-1)" "unprognostic (3.37e-3)" "unprognostic (1.84e-2)" "unprognostic (1.97e-2)" "unprognostic (3.94e-2)" THBS3 ENSG00000169231 "Thrombospondin 3" P49746 1 155195588-155209051 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Late spermatids: 1592.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Rhabdoid: 98.3" "Adipose subcutaneous - Adipose progenitor cells, Colon - Enteric glia cells, Heart muscle - Fibroblasts, Skeletal muscle - Fibroblasts, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA006293, HPA073242" Approved Approved Vesicles "Secreted to extracellular matrix" "Cell adhesion" NA NA 35000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 5: Rhabdoid - Unknown function" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 3 Vesicles "HPA006293: , HPA073242: " "unprognostic (1.10e-1)" "unprognostic (1.58e-1)" "unprognostic (8.59e-2)" "unprognostic (1.06e-3)" "unprognostic (1.67e-2)" "unprognostic (1.32e-1)" "unprognostic (4.21e-1)" "unprognostic (2.48e-2)" "unprognostic (2.07e-1)" "unprognostic (6.27e-2)" "potential prognostic unfavorable (9.72e-6)" "unprognostic (1.94e-2)" "unprognostic (4.37e-3)" "unprognostic (7.01e-2)" "unprognostic (1.91e-3)" "unprognostic (1.65e-1)" "unprognostic (4.28e-2)" "unprognostic (8.26e-2)" "unprognostic (1.99e-1)" "unprognostic (8.19e-2)" "unprognostic (1.23e-1)" "unprognostic (6.40e-2)" "unprognostic (4.48e-1)" "unprognostic (5.49e-2)" "unprognostic (9.94e-3)" "unprognostic (5.70e-2)" "unprognostic (1.02e-1)" "unprognostic (2.57e-2)" "unprognostic (6.09e-2)" "unprognostic (8.30e-3)" "unprognostic (3.53e-1)" THBS4 ENSG00000113296 "Thrombospondin 4" P35443 5 79991311-80083287 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion, Tissue remodeling, Unfolded protein response" "Growth factor, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 203.6;heart muscle: 157.1;smooth muscle: 234.9;tongue: 200.5" "Cell type enhanced" "Detected in many" "Astrocytes: 67.8;Cone photoreceptor cells: 113.9;Fibro-adipogenic progenitors: 165.3;Gonadotrophs: 256.1;Oligodendrocyte progenitor cells: 131.7;Pericytes: 119.5;Pituitary stem cells: 83.7;Prostatic glandular cells: 84.3" "Cell type enhanced" "Detected in all" "oligodendrocyte precursor cell: 163.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 46 "eosinophil: 4.6" "Lineage enriched" "Detected in single" 46 "granulocytes: 4.6" "Low cancer specificity" "Detected in many" "Pituitary gland - Gonadotropes, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Region enriched" "Detected in many" 8 "white matter: 85.8" "Region enriched" "Detected in many" 29 "spinal cord: 117.4" "CAB004597, HPA042426" Approved Approved Vesicles "Secreted to extracellular matrix" "Growth factor" NA NA 740000000 "Cluster 22: Eosinophils - Transcription" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" Vesicles "CAB004597: , HPA042426: " "unprognostic (1.30e-1)" "unprognostic (2.41e-1)" "unprognostic (4.27e-2)" "potential prognostic favorable (4.40e-4)" "unprognostic (1.07e-2)" "unprognostic (6.73e-2)" "unprognostic (4.09e-2)" "unprognostic (7.38e-2)" "unprognostic (1.12e-1)" "unprognostic (1.58e-1)" "unprognostic (1.60e-1)" "unprognostic (4.80e-3)" "unprognostic (9.17e-2)" "unprognostic (1.80e-1)" "unprognostic (6.85e-2)" "unprognostic (7.69e-2)" "unprognostic (1.63e-1)" "unprognostic (3.98e-2)" "unprognostic (1.20e-1)" "unprognostic (3.23e-1)" "unprognostic (2.45e-1)" "unprognostic (1.93e-1)" "unprognostic (3.19e-1)" "unprognostic (4.90e-2)" "unprognostic (7.94e-3)" "unprognostic (9.87e-2)" "unprognostic (1.26e-2)" "unprognostic (1.30e-2)" "unprognostic (1.35e-3)" "unprognostic (1.39e-1)" THEG "CT56, THEG1" ENSG00000105549 "Theg spermatid protein" Q9P2T0 19 361747-376026 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "testis: 40.2" "Cell type enriched" "Detected in some" 6 "Late spermatids: 994.7" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 11.4;prostate cancer: 9.8" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA078077 Approved "Cytosol,Equatorial segment,Principal piece,Annulus" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 53: Neurons - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 6 "Cytosol, Equatorial segment, Principal piece, Annulus" "HPA078077: " "unprognostic (2.02e-2)" "unprognostic (1.60e-1)" "unprognostic (2.66e-1)" THEGL ENSG00000249693 "Theg spermatid protein like" P0DJG4 4 56530606-56603507 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "testis: 3.3" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 10.6;Choroid plexus epithelial cells: 7.2;Early spermatids: 54.9;Epididymal efferent duct ciliated cells: 10.1;Late primary spermatocytes: 36.4;Late spermatids: 33.0;Retinal pigment epithelial cells: 8.5" "Cell type enhanced" "Detected in many" "ependymal cell: 6.9" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" HPA068093 Uncertain Approved "Principal piece" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 23: Choroid plexus - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" "Principal piece" "HPA068093: " THEM4 CTMP ENSG00000159445 "Thioesterase superfamily member 4" Q5T1C6 1 151870866-151909637 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Fatty acid metabolism, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" HPA028161 Approved NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 42: Retina - Visual perception" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 9: T-cells - Adaptive immunity: Regulation" 10 "HPA028161: " "unprognostic (8.43e-3)" "unprognostic (2.24e-1)" "unprognostic (1.38e-2)" "unprognostic (1.02e-1)" "unprognostic (1.31e-1)" "unprognostic (3.09e-2)" "unprognostic (1.46e-1)" "unprognostic (8.23e-2)" "unprognostic (2.89e-2)" "potential prognostic unfavorable (6.34e-4)" "unprognostic (2.61e-2)" "unprognostic (1.76e-1)" "unprognostic (1.35e-1)" "potential prognostic unfavorable (9.01e-4)" "unprognostic (1.83e-1)" "unprognostic (7.82e-2)" "unprognostic (1.92e-1)" "unprognostic (5.31e-3)" "unprognostic (1.89e-1)" "unprognostic (2.63e-1)" "unprognostic (2.08e-2)" "unprognostic (7.66e-2)" "unprognostic (1.83e-1)" "unprognostic (4.96e-3)" "unprognostic (1.81e-1)" "unprognostic (1.20e-1)" "unprognostic (6.21e-2)" "unprognostic (1.43e-1)" "unprognostic (1.43e-1)" "unprognostic (1.65e-2)" "unprognostic (1.81e-2)" THEM5 FLJ37964 ENSG00000196407 "Thioesterase superfamily member 5" Q8N1Q8 1 151847101-151853712 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 22 "skin 1: 137.8" "Group enriched" "Detected in some" 6 "Platelets: 67.7;Suprabasal keratinocytes: 80.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "MAIT T-cell: 1.7" "Lineage enriched" "Detected in single" 6 "T-cells: 1.7" "Cancer enhanced" "Detected in many" "lymphoma: 10.7" "Adipose visceral - Mesothelial cells, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 37: Skin - Keratinization" "Cluster 53: Neurons - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 12 "unprognostic (4.14e-2)" "unprognostic (2.16e-2)" "unprognostic (1.05e-2)" "unprognostic (1.38e-1)" "unprognostic (2.13e-1)" "unprognostic (4.58e-2)" "unprognostic (7.09e-3)" "unprognostic (1.35e-2)" "unprognostic (2.07e-1)" "unprognostic (2.28e-1)" "unprognostic (1.88e-3)" "unprognostic (1.41e-1)" "unprognostic (5.46e-2)" "unprognostic (3.79e-2)" "unprognostic (2.84e-2)" "unprognostic (7.63e-2)" "unprognostic (1.84e-1)" "unprognostic (5.43e-2)" "unprognostic (1.13e-1)" "unprognostic (2.57e-3)" "unprognostic (7.73e-3)" "unprognostic (7.78e-2)" "unprognostic (2.32e-3)" "unprognostic (3.15e-2)" "unprognostic (1.26e-1)" "unprognostic (2.34e-2)" "unprognostic (3.03e-1)" "unprognostic (3.09e-2)" "potential prognostic unfavorable (8.42e-4)" THEM6 "C8orf55, DSCD75" ENSG00000130193 "Thioesterase superfamily member 6" Q8WUY1 8 142727223-142736927 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 75.9;Urothelial cells: 51.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023255 Uncertain Approved "Nuclear speckles,Cytosol" "Secreted - unknown location" "No annotated function" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 18: Non-specific - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 31 "Nuclear speckles, Cytosol" "HPA023255: " "potential prognostic favorable (9.51e-5)" "unprognostic (6.20e-3)" "unprognostic (1.04e-1)" "unprognostic (3.45e-2)" "unprognostic (5.22e-3)" "unprognostic (1.02e-1)" "unprognostic (8.93e-2)" "unprognostic (1.62e-1)" "unprognostic (8.60e-2)" "potential prognostic favorable (3.55e-7)" "unprognostic (3.38e-2)" "unprognostic (8.58e-3)" "unprognostic (2.41e-2)" "unprognostic (6.48e-2)" "unprognostic (4.32e-1)" "unprognostic (1.09e-1)" "unprognostic (7.51e-2)" "unprognostic (2.78e-1)" "unprognostic (9.68e-2)" "unprognostic (8.38e-2)" "unprognostic (4.83e-2)" "unprognostic (7.00e-2)" "unprognostic (1.86e-1)" "unprognostic (2.63e-1)" "unprognostic (1.93e-1)" "unprognostic (1.67e-2)" "unprognostic (8.83e-2)" "unprognostic (5.58e-2)" "unprognostic (6.36e-2)" THEMIS "bA325O24.3, bA325O24.4, C6orf190, C6orf207, FLJ40584, TSEPA" ENSG00000172673 "Thymocyte selection associated" Q8N1K5 6 127708072-127918631 "Predicted intracellular proteins" "Adaptive immunity, Immunity" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "lymphoid tissue: 29.1" "Cell type enriched" "Detected in some" 8 "T-cells: 130.2" "Cell type enriched" "Detected in many" 14 "leukocyte: 1445.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 21 "gdT-cell: 27.3;MAIT T-cell: 32.4;memory CD4 T-cell: 32.5;memory CD8 T-cell: 48.9;naive CD4 T-cell: 30.6;naive CD8 T-cell: 57.0" "Lineage enriched" "Detected in single" 83 "T-cells: 57.0" "Cancer enhanced" "Detected in some" "Leukemia: 4.0;lymphoma: 2.9;Myeloma: 6.9" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Minor Salivary Gland - T-cells, Pancreas - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Spleen - T-cells, Stomach - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA031422, HPA031425" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 11: T-cells - Unknown function" "Cluster 80: Thymus - Adaptive immune response" "Cluster 53: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 102: Non-specific - Mixed function" 5 Cytosol Nucleoplasm "HPA031422: , HPA031425: " "unprognostic (3.40e-1)" "unprognostic (1.20e-1)" "unprognostic (9.59e-2)" "unprognostic (1.38e-2)" "unprognostic (7.70e-2)" "unprognostic (2.58e-1)" "unprognostic (5.22e-2)" "unprognostic (3.31e-1)" "unprognostic (3.26e-2)" "unprognostic (9.28e-2)" "unprognostic (3.47e-2)" THEMIS2 "C1orf38, ICB-1" ENSG00000130775 "Thymocyte selection associated family member 2" Q5TEJ8 1 27872543-27886685 "Predicted intracellular proteins" "Immunity, Inflammatory response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 203.3;lymphoid tissue: 117.7" "Cell type enhanced" "Detected in many" "cDC: 123.7;Kupffer cells: 159.9;Macrophages: 142.6;Monocyte progenitors: 62.3;monocytes: 193.7;Neutrophil progenitors: 75.7;Neutrophils: 377.7;pDCs: 156.4;Plasma cells: 88.8" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 37.8;leukocyte: 37.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 403.9;eosinophil: 341.9;intermediate monocyte: 442.1;myeloid DC: 310.1;neutrophil: 500.4;non-classical monocyte: 457.0;plasmacytoid DC: 125.4" "Group enriched" "Detected in all" 6 "dendritic cells: 310.1;granulocytes: 500.4;monocytes: 457.0" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Pituitary gland - Macrophages, Testis - Sertoli cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA027513, HPA031096" Uncertain Approved Nucleoplasm NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 30: White matter - Myelination" "Cluster 55: Lymphoma - Immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 1 Nucleoplasm "HPA027513: , HPA031096: " "unprognostic (2.83e-1)" "unprognostic (9.26e-2)" "unprognostic (8.03e-2)" "unprognostic (2.56e-1)" "unprognostic (1.61e-1)" "unprognostic (2.26e-2)" "unprognostic (9.31e-2)" "unprognostic (2.27e-2)" "unprognostic (2.88e-1)" "unprognostic (4.85e-3)" "unprognostic (1.75e-2)" "unprognostic (8.57e-2)" "unprognostic (2.94e-1)" "unprognostic (3.92e-2)" "unprognostic (1.69e-2)" "unprognostic (5.45e-3)" "unprognostic (5.43e-2)" "unprognostic (1.53e-3)" "unprognostic (3.07e-2)" "unprognostic (1.96e-2)" "unprognostic (1.40e-1)" "unprognostic (3.47e-1)" "unprognostic (1.03e-1)" "unprognostic (2.38e-3)" "unprognostic (6.98e-2)" "unprognostic (1.04e-2)" "unprognostic (5.87e-3)" "unprognostic (2.76e-2)" "unprognostic (1.05e-1)" THG1L "FLJ11601, FLJ20546, hTHG1, ICF45, IHG-1" ENSG00000113272 "TRNA-histidine guanylyltransferase 1 like" Q9NWX6 5 157731420-157741449 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "Nucleotidyltransferase, Transferase" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 54.2;Early spermatids: 80.8;Late primary spermatocytes: 91.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035877, HPA035878" Approved NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 25: Non-specific - Ribosome" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 7 "HPA035877: , HPA035878: " "unprognostic (1.11e-1)" "unprognostic (1.65e-1)" "unprognostic (2.74e-1)" "unprognostic (5.21e-2)" "unprognostic (3.31e-2)" "unprognostic (4.39e-2)" "unprognostic (3.56e-1)" "unprognostic (3.60e-1)" "unprognostic (1.79e-2)" "unprognostic (2.93e-2)" "validated prognostic favorable (8.38e-5)" "validated prognostic favorable (3.79e-5)" "unprognostic (2.10e-1)" "unprognostic (4.02e-2)" "unprognostic (1.41e-1)" "unprognostic (1.68e-3)" "unprognostic (1.39e-2)" "unprognostic (4.48e-1)" "unprognostic (1.71e-2)" "unprognostic (1.75e-2)" "unprognostic (1.44e-2)" "unprognostic (1.08e-1)" "unprognostic (2.02e-1)" "unprognostic (2.37e-1)" "unprognostic (1.42e-3)" "unprognostic (7.57e-2)" "unprognostic (1.52e-2)" "unprognostic (3.04e-1)" "unprognostic (1.33e-1)" "unprognostic (1.18e-1)" "unprognostic (1.60e-2)" THNSL1 "FLJ22002, TSH1" ENSG00000185875 "Threonine synthase like 1" Q8IYQ7 10 25016612-25026664 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 20.0" "Cell type enhanced" "Detected in some" "Astrocytes: 6.1;Bergmann glia: 5.4;Brain excitatory neurons: 7.7;Brain inhibitory neurons: 9.0;Choroid plexus epithelial cells: 5.7;Distal convoluted tubule cells: 5.6;Ependymal cells: 6.5;Loop of henle epithelial cells: 5.2;Microglia: 7.6;Oligodendrocyte progenitor cells: 5.9;Oligodendrocytes: 8.2;Other brain neurons: 9.7;Podocytes: 5.2;Proximal tubule cells: 4.9;Renal collecting duct principal cells: 4.6;Renal connecting tubule cells: 3.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037585 Uncertain Approved "Nuclear bodies,Mitochondria,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 52: Non-specific - Mitochondria" "Cluster 98: Neurons - Neurotransmission & signaling" 7 "Nuclear bodies, Cytosol" Mitochondria "HPA037585: " "unprognostic (2.68e-1)" "unprognostic (1.33e-1)" "unprognostic (2.53e-1)" "unprognostic (1.40e-1)" "unprognostic (1.11e-1)" "unprognostic (1.29e-1)" "unprognostic (1.55e-1)" "unprognostic (5.32e-3)" "unprognostic (1.40e-1)" "unprognostic (3.05e-3)" "potential prognostic favorable (1.67e-7)" "unprognostic (6.73e-3)" "unprognostic (4.51e-2)" "unprognostic (5.15e-2)" "unprognostic (3.07e-2)" "unprognostic (1.09e-1)" "unprognostic (9.48e-2)" "unprognostic (5.81e-2)" "unprognostic (1.04e-1)" "unprognostic (4.06e-1)" "unprognostic (1.39e-2)" "unprognostic (1.35e-2)" "unprognostic (8.15e-3)" "unprognostic (6.99e-2)" "unprognostic (8.16e-2)" "unprognostic (1.97e-1)" "unprognostic (3.80e-1)" "unprognostic (2.20e-1)" "unprognostic (1.69e-1)" "unprognostic (4.61e-2)" "unprognostic (1.55e-1)" THNSL2 "FLJ10916, SOFAT, TSH2" ENSG00000144115 "Threonine synthase like 2" Q86YJ6 2 88170295-88186636 "Predicted intracellular proteins, Predicted secreted proteins" "Cytokine, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hepatocytes: 63.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035395 Approved "Secreted - unknown location" Cytokine NA NA "Cluster 76: Non-specific - Metabolism" "Cluster 46: Brainstem - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 63: Cytotrophoblasts - Basic cellular functions" "HPA035395: " "unprognostic (1.08e-1)" "unprognostic (3.92e-3)" "unprognostic (2.69e-1)" "unprognostic (3.05e-1)" "unprognostic (5.99e-2)" "unprognostic (4.10e-2)" "unprognostic (2.11e-2)" "unprognostic (5.06e-2)" "unprognostic (6.53e-2)" "unprognostic (6.74e-2)" "potential prognostic favorable (7.89e-6)" "unprognostic (4.57e-1)" "potential prognostic favorable (2.45e-5)" "unprognostic (9.96e-2)" "unprognostic (1.71e-2)" "unprognostic (7.10e-2)" "unprognostic (1.47e-1)" "unprognostic (1.49e-1)" "unprognostic (4.48e-2)" "unprognostic (2.76e-1)" "unprognostic (2.41e-1)" "unprognostic (1.13e-1)" "unprognostic (1.76e-2)" "unprognostic (6.26e-2)" "unprognostic (2.88e-1)" "unprognostic (1.67e-1)" "unprognostic (2.42e-1)" "unprognostic (7.47e-2)" "unprognostic (2.50e-1)" "unprognostic (5.00e-2)" "unprognostic (2.07e-1)" THOC1 "HPR1, P84" ENSG00000079134 "THO complex subunit 1" Q96FV9 18 214520-268050 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, mRNA processing, mRNA splicing, mRNA transport, Transcription, Transcription regulation, Transport" "DNA-binding, RNA-binding" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019096, HPA019687" Enhanced Enhanced "Nuclear speckles" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 39: Testis - Nuclear processes" "Cluster 11: White matter - Signal transduction" "Cluster 13: Non-specific - Mixed function" "Cluster 7: Non-specific - Transcription" 75 "Nuclear speckles" "HPA019096: , HPA019687: " "unprognostic (1.17e-2)" "unprognostic (1.21e-1)" "unprognostic (8.05e-2)" "unprognostic (6.03e-2)" "unprognostic (1.79e-1)" "unprognostic (1.29e-2)" "unprognostic (7.69e-2)" "unprognostic (1.17e-2)" "unprognostic (3.47e-3)" "unprognostic (4.08e-2)" "potential prognostic favorable (9.50e-6)" "unprognostic (3.43e-2)" "unprognostic (2.41e-1)" "potential prognostic unfavorable (3.81e-7)" "unprognostic (2.03e-2)" "unprognostic (1.73e-3)" "unprognostic (2.14e-1)" "unprognostic (6.10e-3)" "unprognostic (2.84e-1)" "unprognostic (1.09e-2)" "unprognostic (1.60e-2)" "unprognostic (7.98e-2)" "potential prognostic unfavorable (1.11e-4)" "unprognostic (8.27e-3)" "unprognostic (1.21e-1)" "unprognostic (4.58e-2)" "unprognostic (1.11e-1)" "unprognostic (5.23e-1)" "unprognostic (2.32e-1)" "unprognostic (1.31e-1)" "unprognostic (1.82e-1)" THOC2 "CXorf3, dJ506G2.1, MRX12, MRX35, THO2" ENSG00000125676 "THO complex subunit 2" Q8NI27 X 123600561-123733056 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, mRNA transport, Transport" RNA-binding "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047921 Supported Approved Nucleoplasm NA NA 3500 "Cluster 3: Non-specific - Nuclear processes" "Cluster 49: Non-specific - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 36: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 36 Nucleoplasm "HPA047921: " "unprognostic (9.76e-2)" "potential prognostic unfavorable (7.09e-4)" "unprognostic (1.14e-1)" "unprognostic (3.76e-1)" "unprognostic (3.21e-1)" "unprognostic (7.66e-2)" "unprognostic (8.00e-3)" "unprognostic (5.92e-2)" "unprognostic (1.08e-1)" "unprognostic (5.10e-3)" "unprognostic (4.33e-2)" "unprognostic (2.30e-1)" "unprognostic (2.95e-3)" "potential prognostic unfavorable (3.67e-6)" "unprognostic (1.10e-2)" "unprognostic (1.87e-1)" "unprognostic (6.11e-3)" "unprognostic (1.69e-2)" "unprognostic (1.22e-1)" "unprognostic (3.99e-1)" "unprognostic (8.23e-2)" "unprognostic (2.29e-1)" "unprognostic (5.03e-3)" "unprognostic (8.24e-2)" "unprognostic (8.67e-2)" "unprognostic (8.37e-3)" "unprognostic (6.71e-2)" "unprognostic (1.93e-2)" "unprognostic (1.20e-1)" "unprognostic (7.74e-2)" "unprognostic (2.86e-1)" THOC3 "MGC5469, TEX1" ENSG00000051596 "THO complex subunit 3" Q96J01 5 175917873-176034680 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, mRNA transport, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 106.0;Esophageal apical cells: 43.4;Late primary spermatocytes: 61.9;Late spermatids: 59.5;Papillary tip epithelial cells: 111.6;Renal connecting tubule cells: 62.2" "Cell type enriched" "Detected in all" 8 "hippocampal dentate gyrus: 125.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042764, HPA044009, HPA045071" Approved Supported Nucleoplasm,Vesicles No No 15000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 29: Forebrain - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 105: Non-specific - Mixed function" 47 Nucleoplasm Vesicles "HPA042764: , HPA044009: , HPA045071: " "potential prognostic unfavorable (1.51e-4)" "unprognostic (2.54e-1)" "unprognostic (7.00e-2)" "potential prognostic favorable (3.28e-4)" "unprognostic (1.24e-1)" "unprognostic (9.94e-2)" "unprognostic (7.99e-2)" "unprognostic (1.23e-1)" "unprognostic (4.46e-3)" "unprognostic (2.52e-2)" "unprognostic (9.38e-2)" "unprognostic (3.12e-1)" "unprognostic (3.80e-3)" "unprognostic (3.46e-3)" "unprognostic (3.69e-3)" "unprognostic (7.52e-3)" "unprognostic (3.27e-2)" "unprognostic (8.66e-3)" "unprognostic (2.48e-1)" "unprognostic (6.64e-2)" "unprognostic (3.82e-2)" "unprognostic (8.41e-3)" "unprognostic (2.53e-1)" "unprognostic (2.60e-2)" "unprognostic (3.86e-3)" "unprognostic (3.30e-2)" "unprognostic (1.17e-1)" "unprognostic (1.34e-1)" "unprognostic (2.67e-1)" "unprognostic (3.45e-1)" "unprognostic (3.16e-1)" THOC5 "C22orf19, Fmip, fSAP79, KIAA0983, PK1.3" ENSG00000100296 "THO complex subunit 5" Q13769 22 29505879-29555216 "Essential proteins, Predicted intracellular proteins" "Differentiation, mRNA processing, mRNA splicing, mRNA transport, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 215.0;Neutrophils: 76.6;Tuft cells: 69.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048402 Supported Nucleoplasm NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 37: Neurons - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 24: Neutrophils - Innate immunity signal integration" 33 Nucleoplasm "HPA048402: " "unprognostic (1.56e-1)" "unprognostic (9.46e-2)" "unprognostic (1.14e-1)" "unprognostic (3.48e-2)" "unprognostic (2.75e-1)" "unprognostic (1.28e-1)" "unprognostic (7.66e-2)" "unprognostic (6.37e-3)" "unprognostic (4.45e-2)" "unprognostic (7.32e-3)" "unprognostic (5.91e-3)" "unprognostic (5.31e-2)" "unprognostic (2.48e-1)" "validated prognostic unfavorable (1.37e-6)" "validated prognostic unfavorable (7.51e-5)" "unprognostic (2.59e-1)" "unprognostic (8.34e-3)" "unprognostic (1.72e-1)" "unprognostic (9.38e-2)" "unprognostic (6.95e-2)" "unprognostic (2.06e-1)" "unprognostic (7.79e-2)" "potential prognostic unfavorable (9.31e-4)" "unprognostic (7.87e-2)" "unprognostic (1.25e-2)" "unprognostic (3.38e-3)" "unprognostic (1.10e-1)" "unprognostic (2.03e-1)" "unprognostic (1.83e-1)" "unprognostic (2.66e-2)" "unprognostic (1.18e-1)" THOC6 "fSAP35, MGC2655, WDR58" ENSG00000131652 "THO complex subunit 6" Q86W42 16 3024027-3027755 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Apoptosis, mRNA processing, mRNA splicing, mRNA transport, Transport" "Developmental protein, RNA-binding" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 123.4;Esophageal basal cells: 75.7;Extravillous trophoblasts: 143.5;Migrating cytotrophoblasts: 152.4;Syncytiotrophoblasts: 80.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052953 Uncertain Supported "Nucleoplasm,Nuclear speckles" No No "Cluster 13: Non-specific - Mitochondria" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 18 "Nucleoplasm, Nuclear speckles" "HPA052953: " "unprognostic (5.98e-2)" "unprognostic (1.34e-1)" "unprognostic (2.35e-1)" "unprognostic (1.21e-1)" "unprognostic (1.14e-1)" "unprognostic (2.12e-1)" "unprognostic (2.82e-2)" "unprognostic (1.38e-2)" "unprognostic (3.40e-1)" "unprognostic (1.16e-1)" "unprognostic (3.04e-3)" "unprognostic (3.11e-1)" "unprognostic (1.97e-1)" "unprognostic (2.39e-2)" "unprognostic (1.96e-2)" "unprognostic (1.46e-1)" "unprognostic (1.63e-2)" "unprognostic (2.85e-1)" "unprognostic (2.79e-2)" "unprognostic (8.59e-2)" "unprognostic (7.26e-2)" "unprognostic (3.68e-2)" "unprognostic (8.13e-2)" "unprognostic (8.32e-3)" "unprognostic (8.73e-2)" "unprognostic (1.09e-1)" "unprognostic (6.95e-2)" "unprognostic (1.54e-1)" "unprognostic (2.28e-1)" "unprognostic (9.82e-2)" "unprognostic (1.61e-1)" THOC7 "FLJ23445, fSAP24, NIF3L1BP1" ENSG00000163634 "THO complex subunit 7" Q6I9Y2 3 63833870-63863868 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, mRNA transport, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal basal cells: 311.2;Esophageal suprabasal cells: 350.2;Megakaryocytes: 327.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044143 Approved Supported "Nuclear speckles,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 97: Non-specific - Cellular respiration" 48 "Nuclear speckles, Cytosol" "HPA044143: " "unprognostic (1.15e-1)" "unprognostic (1.99e-1)" "unprognostic (3.00e-2)" "unprognostic (6.51e-2)" "unprognostic (4.12e-2)" "unprognostic (1.36e-1)" "unprognostic (1.80e-3)" "unprognostic (2.39e-2)" "unprognostic (2.09e-1)" "unprognostic (9.21e-3)" "unprognostic (2.44e-1)" "unprognostic (3.11e-1)" "unprognostic (3.93e-2)" "validated prognostic unfavorable (7.36e-6)" "validated prognostic unfavorable (5.21e-5)" "unprognostic (4.43e-3)" "potential prognostic unfavorable (4.84e-4)" "unprognostic (1.10e-2)" "unprognostic (6.00e-2)" "unprognostic (1.52e-3)" "unprognostic (1.77e-1)" "unprognostic (5.40e-3)" "unprognostic (4.49e-2)" "unprognostic (8.62e-2)" "unprognostic (8.86e-2)" "unprognostic (3.27e-1)" "unprognostic (4.92e-3)" "unprognostic (1.40e-1)" "unprognostic (3.43e-2)" "unprognostic (2.13e-1)" "unprognostic (1.83e-2)" THOP1 ENSG00000172009 "Thimet oligopeptidase 1" P52888 19 2785503-2815807 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 127.3;Enterocytes: 281.0;Hepatocytes: 99.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025497, HPA035262" Uncertain Supported Cytosol NA NA 1700000 "Cluster 14: Non-specific - Unknown function" "Cluster 67: Testis - Mixed function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 5 Cytosol "CAB025497: , HPA035262: " "unprognostic (2.61e-1)" "unprognostic (2.83e-2)" "unprognostic (5.27e-2)" "unprognostic (2.80e-2)" "unprognostic (3.40e-2)" "unprognostic (4.63e-1)" "unprognostic (1.79e-1)" "unprognostic (1.14e-1)" "unprognostic (3.05e-2)" "unprognostic (4.22e-2)" "unprognostic (7.80e-3)" "unprognostic (1.41e-1)" "unprognostic (1.63e-1)" "unprognostic (1.24e-1)" "unprognostic (5.54e-2)" "unprognostic (1.84e-3)" "unprognostic (1.06e-2)" "unprognostic (5.72e-2)" "unprognostic (6.98e-2)" "unprognostic (3.65e-1)" "potential prognostic favorable (7.76e-4)" "unprognostic (3.58e-3)" "unprognostic (7.49e-2)" "unprognostic (5.45e-2)" "unprognostic (1.54e-1)" "potential prognostic favorable (7.11e-4)" "unprognostic (1.74e-1)" "unprognostic (1.03e-2)" "unprognostic (2.76e-1)" "unprognostic (2.04e-1)" "unprognostic (2.66e-2)" THPO "MGDF, MPLLG, TPO" ENSG00000090534 Thrombopoietin P40225 3 184371935-184381968 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Cytokine, Hormone" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 33.7" "Cell type enhanced" "Detected in some" "Adipocytes: 3.7;Brain excitatory neurons: 2.4;Decidual stromal cells: 2.7;Early spermatids: 2.2;Endometrial stromal cells: 2.5;Epicardial cells: 2.3;Fibroblasts: 3.2;Hepatocytes: 15.1;Kupffer cells: 3.1;Late primary spermatocytes: 2.7;Late spermatids: 8.5;Myosatellite cells: 3.6;Pericytes: 4.5;Vascular smooth muscle cells: 2.8" "Cell type enhanced" "Detected in many" "upper-layer intratelencephalic: 5.6" "Cancer enriched" "Detected in many" 4 "Liver Hepatocellular Carcinoma (TCGA): 12.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 4.1;lymphoma: 3.1" "Kidney - Proximal tubular cells, Prostate - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted to blood" Cytokine NA NA 1070000 "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 34: Non-specific - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "unprognostic (3.77e-2)" "unprognostic (3.69e-2)" "unprognostic (3.72e-2)" "unprognostic (4.03e-1)" "unprognostic (1.01e-1)" "unprognostic (9.92e-2)" "unprognostic (2.08e-2)" "unprognostic (8.11e-3)" "unprognostic (1.87e-3)" "unprognostic (3.19e-1)" "unprognostic (1.41e-1)" "unprognostic (2.81e-3)" "unprognostic (3.91e-1)" "unprognostic (5.92e-2)" THRA "AR7, EAR-7.1/EAR-7.2, ERBA, ERBA1, NR1A1, THRA1, THRA2, THRA3, TRalpha" ENSG00000126351 "Thyroid hormone receptor alpha" P10827 17 40058290-40093867 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, Congenital hypothyroidism, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "brain: 400.8" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 138.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009654, CAB023349" Approved Uncertain Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 62: Smooth muscle cells - Muscle contraction" 34 Cytosol "CAB023349: , HPA009654: " "unprognostic (2.84e-1)" "unprognostic (8.45e-2)" "unprognostic (7.47e-2)" "unprognostic (3.78e-2)" "unprognostic (6.22e-2)" "unprognostic (1.67e-2)" "unprognostic (1.12e-1)" "unprognostic (8.25e-3)" "unprognostic (2.41e-1)" "unprognostic (2.04e-1)" "validated prognostic favorable (1.16e-7)" "validated prognostic favorable (5.38e-4)" "unprognostic (2.08e-3)" "unprognostic (8.49e-3)" "unprognostic (5.85e-2)" "unprognostic (1.01e-3)" "unprognostic (1.64e-1)" "unprognostic (8.24e-2)" "unprognostic (2.44e-2)" "unprognostic (1.13e-1)" "unprognostic (9.93e-2)" "unprognostic (1.30e-1)" "unprognostic (4.40e-2)" "unprognostic (1.52e-2)" "unprognostic (1.77e-3)" "unprognostic (8.83e-2)" "unprognostic (8.32e-2)" "unprognostic (6.68e-2)" "unprognostic (1.77e-1)" "unprognostic (3.38e-1)" "unprognostic (4.01e-2)" THRAP3 "BCLAF2, TRAP150" ENSG00000054118 "Thyroid hormone receptor associated protein 3" Q9Y2W1 1 36224432-36305357 "Plasma proteins, Predicted intracellular proteins" "Biological rhythms, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Activator, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012041, CAB017472, HPA063765" Supported Enhanced "Nuclear speckles" NA NA 31000 "Cluster 41: Basophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 37: Non-specific - mRNA processing" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 95 "Nuclear speckles" "CAB017472: , HPA012041: , HPA063765: " "unprognostic (1.60e-2)" "unprognostic (3.14e-1)" "unprognostic (2.17e-1)" "unprognostic (1.22e-2)" "unprognostic (4.98e-2)" "unprognostic (1.80e-1)" "unprognostic (2.20e-2)" "unprognostic (6.71e-2)" "unprognostic (2.00e-1)" "unprognostic (3.61e-3)" "potential prognostic favorable (7.93e-5)" "unprognostic (8.36e-3)" "unprognostic (1.47e-1)" "potential prognostic unfavorable (5.06e-4)" "unprognostic (2.66e-2)" "unprognostic (1.93e-1)" "unprognostic (3.34e-2)" "unprognostic (1.29e-1)" "unprognostic (5.02e-2)" "unprognostic (1.39e-2)" "unprognostic (2.46e-1)" "unprognostic (7.40e-2)" "unprognostic (1.30e-1)" "unprognostic (1.06e-1)" "unprognostic (1.21e-1)" "unprognostic (9.54e-3)" "unprognostic (2.58e-1)" "unprognostic (5.94e-2)" "unprognostic (2.18e-1)" "unprognostic (1.65e-1)" "unprognostic (3.97e-2)" THRB "ERBA-BETA, ERBA2, GRTH, NR1A2, PRTH, THR1, THRB1, THRB2, TRbeta" ENSG00000151090 "Thyroid hormone receptor beta" P10828 3 24117153-24495756 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, Deafness, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 875.7;Lactotrophs: 770.9;Myonuclei: 1383.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 7.2;naive B-cell: 2.3" "Group enriched" "Detected in many" 15 "B-cells: 2.3;granulocytes: 7.2" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 36.0" "Liver - Hepatocytes, Pituitary gland - Lactotropes, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002008, CAB002009, HPA061035" Approved Supported "Nuclear bodies" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 53: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 55: Myocytes - Oxidative muscle function" 18 "Nuclear bodies" "CAB002008: , CAB002009: , HPA061035: " "unprognostic (4.40e-3)" "unprognostic (1.87e-1)" "unprognostic (1.16e-1)" "unprognostic (9.05e-2)" "unprognostic (4.98e-2)" "unprognostic (1.24e-2)" "unprognostic (2.97e-1)" "unprognostic (6.13e-2)" "unprognostic (3.55e-2)" "unprognostic (8.18e-2)" "validated prognostic favorable (1.53e-10)" "validated prognostic favorable (5.86e-4)" "unprognostic (1.74e-2)" "unprognostic (1.92e-1)" "unprognostic (1.44e-2)" "unprognostic (1.92e-2)" "unprognostic (2.23e-1)" "unprognostic (2.58e-2)" "unprognostic (2.63e-2)" "unprognostic (7.72e-2)" "unprognostic (8.92e-3)" "unprognostic (1.94e-1)" "unprognostic (9.52e-2)" "unprognostic (6.19e-2)" "unprognostic (1.87e-1)" "unprognostic (5.30e-2)" "unprognostic (1.17e-1)" "potential prognostic unfavorable (7.53e-4)" "unprognostic (1.98e-1)" "unprognostic (2.79e-3)" "unprognostic (1.37e-3)" THRSP "Lpgp, LPGP1, S14, SPOT14, THRP" ENSG00000151365 "Thyroid hormone responsive" Q92748 11 78063861-78068351 "Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 197.2;liver: 411.6" "Group enriched" "Detected in some" 6 "Adipocytes: 43.4;Breast lactating cells: 133.7;Epididymal clear cells: 79.6;Hepatocytes: 87.8;Oocytes: 41.4" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 39.0;Liver Hepatocellular Carcinoma (TCGA): 58.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "breast cancer: 12.4;lymphoma: 6.2" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Minor Salivary Gland - Adipocytes (Minor salivary gland), Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040642 Approved Approved Nucleoplasm NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 35: Non-specific - DNA binding" "Cluster 27: Breast cancer - Unknown function" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 6 Nucleoplasm "HPA040642: " "unprognostic (3.61e-2)" "unprognostic (5.34e-2)" "unprognostic (1.17e-1)" "potential prognostic unfavorable (2.27e-5)" "unprognostic (2.12e-2)" "potential prognostic favorable (2.75e-5)" "unprognostic (8.95e-2)" "unprognostic (2.57e-1)" "potential prognostic favorable (5.93e-4)" "unprognostic (9.95e-2)" THSD1 TMTSP ENSG00000136114 "Thrombospondin type 1 domain containing 1" Q9NS62 13 52377167-52416373 "Disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 42.0;Epididymal basal cells: 39.6;Fibro-adipogenic progenitors: 30.7;Lymphatic endothelial cells: 74.7;Myosatellite cells: 21.7;Retinal bipolar cells: 27.5;Retinal ganglion cells: 46.4;Vascular endothelial cells: 43.3" "Group enriched" "Detected in all" 4 "astrocyte: 28.8;endothelial cell: 105.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Endothelial cells, Colon - Endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012611, CAB020796, HPA071106" Supported Supported Cytosol "Intracellular and membrane" "No annotated function" No No 260000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 51: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" Cytosol "CAB020796: , HPA012611: , HPA071106: " "unprognostic (6.78e-2)" "unprognostic (6.95e-2)" "unprognostic (4.48e-1)" "unprognostic (1.39e-2)" "unprognostic (1.10e-1)" "unprognostic (2.03e-2)" "unprognostic (3.62e-1)" "unprognostic (3.88e-2)" "unprognostic (3.03e-2)" "unprognostic (1.31e-1)" "unprognostic (1.75e-3)" "potential prognostic favorable (7.89e-5)" "unprognostic (5.07e-2)" "unprognostic (1.17e-1)" "unprognostic (1.45e-3)" "unprognostic (1.05e-3)" "unprognostic (1.44e-1)" "unprognostic (2.17e-2)" "unprognostic (2.18e-2)" "unprognostic (1.13e-3)" "unprognostic (2.63e-2)" "unprognostic (1.68e-1)" "unprognostic (9.25e-3)" "unprognostic (2.96e-2)" "unprognostic (1.30e-1)" "unprognostic (1.47e-2)" "unprognostic (2.41e-1)" "unprognostic (6.57e-2)" "unprognostic (8.61e-2)" THSD4 "ADAMTSL6, FLJ13710, FVSY9334, PRO34005" ENSG00000187720 "Thrombospondin type 1 domain containing 4" Q6ZMP0 15 71096952-71783383 "Disease related genes, Human disease related genes, Predicted secreted proteins" Hydrolase "Aortic aneurysm" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 67.4" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 1633.6;Breast hormone-responsive cells: 775.5;Cardiomyocytes: 2233.4;Prostatic glandular cells: 1259.3" "Group enriched" "Detected in all" 4 "endothelial cell: 1745.1;fibroblast: 1030.1" "Cancer enhanced" "Detected in all" "Ovary Serous Cystadenocarcinoma (TCGA): 64.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Kidney - Fibroblasts, Prostate - Prostate basal glandular cells, Testis - Peritubular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "spinal cord: 52.3" "Secreted - unknown location" Enzyme NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 20 "unprognostic (2.25e-1)" "unprognostic (1.62e-1)" "unprognostic (5.60e-1)" "unprognostic (6.46e-3)" "unprognostic (8.77e-2)" "unprognostic (1.71e-1)" "unprognostic (1.53e-1)" "unprognostic (7.49e-2)" "unprognostic (2.08e-2)" "unprognostic (1.47e-1)" "unprognostic (3.79e-1)" "unprognostic (3.40e-2)" "unprognostic (6.91e-3)" "unprognostic (2.75e-2)" "unprognostic (1.58e-1)" "unprognostic (2.61e-1)" "unprognostic (5.49e-2)" "unprognostic (1.35e-1)" "unprognostic (2.27e-1)" "unprognostic (1.09e-2)" "unprognostic (4.98e-1)" "unprognostic (1.96e-1)" "unprognostic (2.36e-1)" "unprognostic (1.12e-1)" "unprognostic (2.05e-2)" "unprognostic (2.04e-1)" "unprognostic (3.02e-2)" "unprognostic (2.17e-1)" "unprognostic (1.07e-1)" "unprognostic (9.81e-3)" "unprognostic (2.26e-1)" THSD7A KIAA0960 ENSG00000005108 "Thrombospondin type 1 domain containing 7A" Q9UPZ6 7 11370365-11832198 "Disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Angiogenesis, Differentiation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 7.0" "Cell type enhanced" "Detected in many" "Lactotrophs: 970.3;Loop of henle epithelial cells: 637.5;Podocytes: 2271.3;Renal collecting duct intercalated cells: 1363.5;Renal collecting duct principal cells: 1063.7;Renal connecting tubule cells: 792.9;Retinal bipolar cells: 620.0;Retinal horizontal cells: 500.8;Somatotrophs: 650.4" "Cell type enhanced" "Detected in all" "LAMP5-LHX6 and Chandelier: 1126.7" "Cancer enriched" "Detected in many" 6 "Kidney Chromophobe (TCGA): 22.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 53 "basophil: 5.3" "Lineage enriched" "Detected in single" 53 "granulocytes: 5.3" "Cancer enriched" "Detected in many" 6 "Neuroblastoma: 11.5" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Minor Salivary Gland - Endothelial cells, Pancreas - Endothelial cells, Pituitary gland - Lactotropes, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000923 Supported "Secreted to blood" "Developmental protein" NA NA 3800000 "Cluster 46: Basophils - Proteolysis" "Cluster 72: Kidney - Transmembrane transport" "Cluster 19: Astrocytes - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 57: Podocytes - Glomerular filtration" 13 "HPA000923: " "unprognostic (4.33e-2)" "unprognostic (4.49e-2)" "unprognostic (5.01e-1)" "unprognostic (1.82e-1)" "unprognostic (4.64e-2)" "validated prognostic favorable (9.03e-6)" "validated prognostic favorable (2.30e-4)" "unprognostic (6.43e-2)" "unprognostic (3.13e-2)" "unprognostic (1.04e-1)" "unprognostic (5.05e-2)" "unprognostic (1.67e-1)" "unprognostic (1.75e-1)" "potential prognostic unfavorable (7.07e-4)" "unprognostic (7.76e-2)" "unprognostic (8.25e-2)" "unprognostic (1.78e-2)" "unprognostic (1.16e-1)" THSD7B KIAA1679 ENSG00000144229 "Thrombospondin type 1 domain containing 7B" Q9C0I4 2 136765545-137677718 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "retina: 18.0" "Group enriched" "Detected in many" 7 "Cone photoreceptor cells: 848.7;Retinal horizontal cells: 1923.2;Rod photoreceptor cells: 1774.3" "Cell type enhanced" "Detected in all" "CGE interneuron: 635.3;lower rhombic lip: 1689.0" "Cancer enhanced" "Detected in some" "Kidney Chromophobe (TCGA): 3.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 3.4;Rhabdoid: 2.7" "Pituitary gland - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA051416, HPA056745" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 42: Retina - Visual perception" "Cluster 49: Hindbrain - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 79: Photoreceptor cells - Phototransduction" 23 Nucleoplasm Cytosol "HPA051416: , HPA056745: " "unprognostic (2.74e-1)" "unprognostic (5.55e-2)" "unprognostic (4.60e-2)" "potential prognostic favorable (5.63e-7)" "unprognostic (3.86e-3)" "unprognostic (2.42e-2)" THSD8 ENSG00000284491 "Thrombospondin type 1 domain containing 8" A0A1W2PP97 19 12802031-12813581 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in many" 4 "Breast myoepithelial cells: 93.9" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" NA NA "Cluster 65: Non-specific - Cell growth & division" THTPA THTPASE ENSG00000259431 "Thiamine triphosphatase" Q9BU02 14 23555988-23560271 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 8.3;Bergmann glia: 10.0;Brain excitatory neurons: 8.5;Brain inhibitory neurons: 8.3;Choroid plexus epithelial cells: 4.6;Ependymal cells: 5.0;Loop of henle epithelial cells: 3.0;Microglia: 6.4;Oligodendrocyte progenitor cells: 6.4;Oligodendrocytes: 10.1;Other brain neurons: 10.9;Podocytes: 3.9;Proximal tubule cells: 3.0;Renal collecting duct principal cells: 3.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028876 Approved Uncertain Nucleoplasm,Nucleoli NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 51: Neurons - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 98: Neurons - Neurotransmission & signaling" 31 Nucleoplasm Nucleoli "HPA028876: " "unprognostic (5.26e-2)" "unprognostic (9.60e-3)" "unprognostic (6.57e-3)" "unprognostic (2.00e-1)" "unprognostic (1.66e-1)" "unprognostic (8.26e-2)" "unprognostic (3.52e-2)" "unprognostic (6.00e-2)" "unprognostic (6.38e-2)" "unprognostic (1.38e-1)" "potential prognostic favorable (1.53e-7)" "unprognostic (3.04e-3)" "potential prognostic favorable (1.63e-4)" "unprognostic (7.10e-2)" "unprognostic (4.01e-2)" "unprognostic (7.59e-2)" "unprognostic (5.46e-2)" "unprognostic (7.21e-3)" "unprognostic (6.85e-2)" "unprognostic (8.46e-3)" "unprognostic (3.57e-1)" "unprognostic (3.83e-2)" "unprognostic (4.17e-1)" "unprognostic (1.55e-1)" "unprognostic (8.78e-2)" "unprognostic (1.56e-1)" "unprognostic (1.61e-1)" "unprognostic (1.09e-2)" "unprognostic (8.32e-2)" "unprognostic (2.16e-1)" "unprognostic (5.90e-2)" THUMPD1 "FLJ20274, Tan1" ENSG00000066654 "THUMP domain containing 1" Q9NXG2 16 20702816-20742084 "Disease related genes, Predicted intracellular proteins" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epicardial cells: 691.3;Fibroblasts: 257.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027851 Approved Approved Cytosol NA NA 6600 "Cluster 3: Non-specific - Nuclear processes" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 54: Non-specific - Transcription" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 15 Cytosol "HPA027851: " "unprognostic (3.69e-2)" "unprognostic (1.27e-2)" "unprognostic (6.95e-2)" "unprognostic (8.18e-2)" "unprognostic (3.49e-2)" "unprognostic (8.08e-2)" "unprognostic (5.03e-1)" "unprognostic (1.62e-3)" "unprognostic (3.80e-1)" "unprognostic (2.09e-2)" "potential prognostic favorable (5.91e-8)" "unprognostic (5.31e-3)" "unprognostic (1.18e-1)" "unprognostic (2.44e-2)" "unprognostic (2.06e-1)" "unprognostic (2.77e-1)" "unprognostic (2.72e-1)" "unprognostic (2.17e-1)" "unprognostic (3.09e-2)" "unprognostic (1.20e-1)" "unprognostic (3.06e-3)" "unprognostic (2.52e-2)" "unprognostic (1.28e-1)" "unprognostic (8.90e-2)" "unprognostic (2.59e-2)" "unprognostic (2.49e-1)" "unprognostic (4.11e-2)" "unprognostic (8.41e-2)" "unprognostic (1.55e-1)" "unprognostic (1.33e-1)" "unprognostic (1.47e-1)" THUMPD2 "C2orf8, MGC2454" ENSG00000138050 "THUMP domain containing 2" Q9BTF0 2 39736060-39779267 "Predicted intracellular proteins" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043042, HPA058025" Approved Uncertain Nucleoplasm Yes No "Cluster 30: Non-specific - DNA binding" "Cluster 24: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 7: Non-specific - Transcription" 2 Nucleoplasm "HPA043042: , HPA058025: " "unprognostic (2.25e-1)" "unprognostic (6.00e-2)" "unprognostic (3.62e-3)" "unprognostic (8.15e-2)" "unprognostic (6.25e-3)" "unprognostic (1.52e-1)" "unprognostic (4.42e-2)" "potential prognostic unfavorable (5.98e-5)" "unprognostic (1.38e-1)" "unprognostic (1.27e-2)" "unprognostic (3.91e-2)" "unprognostic (1.72e-1)" "unprognostic (1.49e-1)" "unprognostic (1.92e-2)" "unprognostic (2.36e-1)" "unprognostic (7.69e-2)" "unprognostic (1.78e-2)" THUMPD3 DKFZP434F091 ENSG00000134077 "THUMP domain containing 3" Q9BV44 3 9362971-9386791 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, RNA-binding, Transferase, tRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 261.3;Late primary spermatocytes: 391.8;Late spermatids: 177.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036170, HPA036171" Approved Enhanced Nucleoli,Cytosol No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 11 Cytosol Nucleoli "HPA036170: , HPA036171: " "unprognostic (3.86e-1)" "unprognostic (3.17e-2)" "unprognostic (3.17e-1)" "unprognostic (1.98e-1)" "unprognostic (2.88e-1)" "unprognostic (8.59e-2)" "unprognostic (1.80e-1)" "unprognostic (1.30e-1)" "unprognostic (4.86e-2)" "unprognostic (1.17e-3)" "potential prognostic favorable (2.22e-5)" "unprognostic (4.40e-1)" "unprognostic (2.42e-1)" "potential prognostic unfavorable (6.08e-6)" "unprognostic (4.27e-2)" "unprognostic (2.94e-3)" "unprognostic (7.88e-3)" "unprognostic (1.28e-1)" "unprognostic (2.63e-1)" "unprognostic (7.50e-2)" "unprognostic (3.39e-2)" "unprognostic (5.66e-3)" "unprognostic (8.51e-2)" "unprognostic (1.90e-2)" "unprognostic (8.62e-3)" "unprognostic (1.05e-1)" "unprognostic (2.02e-1)" "unprognostic (9.53e-2)" "unprognostic (1.59e-1)" "unprognostic (6.93e-2)" "unprognostic (2.60e-1)" THY1 CD90 ENSG00000154096 "Thy-1 cell surface antigen" P04216 11 119415476-119424985 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 241.6;smooth muscle: 284.1;urinary bladder: 201.6" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 130.8;Brain inhibitory neurons: 179.2;Breast myoepithelial cells: 210.1;Decidual stromal cells: 487.3;Endometrial stromal cells: 92.9;Epididymal efferent duct ciliated cells: 208.6;Fibroblasts: 153.4;Hepatic stellate cells: 284.0;Müller glia: 101.0;Oligodendrocyte progenitor cells: 105.4;Other brain neurons: 167.9;Pericytes: 146.4;Peritubular myoid cells: 78.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 459.1;thyroid cancer: 259.2" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Liver - Hepatic stellate cells, Lung - Fibroblasts_2, Pituitary gland - Lactotropes, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblasts_1, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003733, CAB068243, CAB068244" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 1200000 "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 5 Nucleoplasm "Plasma membrane" "CAB068243: , CAB068244: , HPA003733: " "unprognostic (3.70e-2)" "unprognostic (4.38e-2)" "unprognostic (1.82e-1)" "unprognostic (6.72e-3)" "unprognostic (2.48e-3)" "unprognostic (1.17e-1)" "potential prognostic unfavorable (4.42e-4)" "unprognostic (3.26e-2)" "unprognostic (1.35e-1)" "unprognostic (1.42e-2)" "unprognostic (1.97e-2)" "unprognostic (3.35e-3)" "unprognostic (3.80e-3)" "unprognostic (1.89e-2)" "unprognostic (2.59e-1)" "unprognostic (6.11e-2)" "unprognostic (1.89e-2)" "unprognostic (2.37e-2)" "unprognostic (1.73e-1)" "unprognostic (1.35e-3)" "unprognostic (3.42e-2)" "unprognostic (5.31e-2)" "unprognostic (4.47e-2)" "unprognostic (3.22e-1)" "unprognostic (2.01e-1)" "unprognostic (6.41e-2)" "unprognostic (2.84e-2)" "unprognostic (1.14e-2)" "unprognostic (2.28e-2)" "unprognostic (4.67e-2)" "unprognostic (3.89e-2)" THYN1 THY28 ENSG00000151500 "Thymocyte nuclear protein 1" Q9P016 11 134248279-134253370 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 7 "Oocytes: 824.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038732, HPA038733" Supported Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 22: Epididymis - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 41: Oocytes - Oogenesis" 1 "Nucleoplasm, Nucleoli fibrillar center" Cytosol "HPA038732: , HPA038733: " "unprognostic (1.44e-1)" "unprognostic (2.67e-1)" "unprognostic (1.54e-1)" "unprognostic (5.38e-2)" "unprognostic (2.02e-1)" "unprognostic (1.31e-2)" "unprognostic (2.26e-2)" "unprognostic (2.75e-3)" "unprognostic (2.70e-1)" "unprognostic (7.76e-3)" "unprognostic (3.77e-3)" "unprognostic (3.45e-2)" "potential prognostic favorable (4.99e-4)" "unprognostic (1.28e-1)" "unprognostic (1.04e-3)" "potential prognostic favorable (3.90e-4)" "unprognostic (2.39e-2)" "unprognostic (1.22e-3)" "unprognostic (1.74e-1)" "unprognostic (7.20e-2)" "unprognostic (1.05e-2)" "unprognostic (4.55e-1)" "unprognostic (5.73e-2)" "unprognostic (1.59e-1)" "potential prognostic favorable (3.22e-5)" "unprognostic (1.87e-1)" "unprognostic (4.90e-3)" "unprognostic (1.34e-1)" "unprognostic (9.73e-2)" "unprognostic (8.90e-3)" "unprognostic (7.82e-2)" TIA1 TIA-1 ENSG00000116001 "TIA1 cytotoxic granule associated RNA binding protein" P31483 2 70209444-70248660 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, mRNA processing, mRNA splicing" RNA-binding "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 27.9;Platelets: 35.2;Tuft cells: 34.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056961 Supported Nucleoplasm,Cytosol NA NA "Cluster 18: Non-specific - Translation" "Cluster 75: Ovary - Mixed function" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 17: Non-specific - RNA processing" 10 Nucleoplasm Cytosol "HPA056961: " "potential prognostic favorable (7.29e-5)" "unprognostic (2.05e-1)" "unprognostic (2.83e-1)" "unprognostic (2.01e-1)" "unprognostic (5.29e-2)" "unprognostic (2.52e-1)" "unprognostic (9.76e-3)" "unprognostic (9.31e-3)" "potential prognostic favorable (2.59e-4)" "unprognostic (7.70e-3)" "unprognostic (2.36e-3)" "unprognostic (3.96e-2)" "unprognostic (9.42e-2)" "unprognostic (3.11e-3)" "unprognostic (4.19e-1)" "unprognostic (1.71e-1)" "unprognostic (3.51e-1)" "unprognostic (6.23e-3)" "unprognostic (3.92e-2)" "unprognostic (1.35e-1)" "unprognostic (3.20e-1)" "unprognostic (3.36e-1)" "unprognostic (6.66e-3)" "unprognostic (5.30e-2)" "unprognostic (2.40e-3)" "unprognostic (3.65e-2)" "unprognostic (1.23e-2)" "unprognostic (5.51e-2)" "unprognostic (1.87e-1)" "unprognostic (3.25e-1)" "unprognostic (2.40e-1)" TIAL1 TIAR ENSG00000151923 "TIA1 cytotoxic granule associated RNA binding protein like 1" Q01085 10 119571802-119597029 "Predicted intracellular proteins" Apoptosis RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA068458, HPA074876" Supported Nucleoplasm,Cytosol NA NA "Cluster 1: T-cells - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 20: Non-specific - Transcription regulation" 10 Nucleoplasm Cytosol "HPA068458: , HPA074876: " "unprognostic (1.29e-3)" "unprognostic (2.37e-2)" "unprognostic (2.11e-1)" "unprognostic (1.07e-2)" "unprognostic (1.10e-2)" "unprognostic (1.42e-1)" "unprognostic (1.72e-2)" "unprognostic (1.31e-2)" "unprognostic (3.72e-2)" "unprognostic (3.29e-2)" "potential prognostic favorable (3.79e-4)" "unprognostic (1.30e-2)" "unprognostic (4.94e-2)" "unprognostic (9.67e-3)" "unprognostic (2.33e-2)" "unprognostic (4.49e-1)" "unprognostic (1.39e-1)" "unprognostic (3.50e-1)" "unprognostic (1.11e-1)" "unprognostic (7.52e-2)" "unprognostic (1.31e-1)" "unprognostic (3.30e-1)" "potential prognostic unfavorable (3.35e-4)" "unprognostic (5.54e-3)" "unprognostic (1.67e-2)" "unprognostic (2.12e-1)" "unprognostic (1.03e-1)" "unprognostic (1.91e-1)" "unprognostic (5.21e-2)" "unprognostic (2.80e-2)" "unprognostic (3.65e-2)" TIAM1 ENSG00000156299 "TIAM Rac1 associated GEF 1" Q13009 21 31118416-31559977 "Disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 264.4" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 848.5;Corticotrophs: 847.3;Epididymal basal cells: 501.8;Esophageal apical cells: 615.2;Esophageal suprabasal cells: 509.4;Microglia: 499.0;Ocular epithelial cells: 708.3;Retinal horizontal cells: 585.0;Suprabasal keratinocytes: 874.0;Urothelial cells: 693.9" "Cell type enhanced" "Detected in all" "upper rhombic lip: 2286.5" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 43.2" "Region enriched" "Detected in all" 4 "cerebellum: 330.3" "Immune cell enhanced" "Detected in many" "T-reg: 33.6" "Group enriched" "Detected in many" 4 "monocytes: 12.4;T-cells: 33.6" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal medulla cells, Pituitary gland - Corticotropes" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 363.0" "CAB010416, HPA034853" Enhanced Supported "Nucleoplasm,Nuclear membrane,Cell Junctions,Cytokinetic bridge,Cytosol" Yes NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 71: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 69: Skin cancer - ECM organization" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 27 "Nucleoplasm, Cell Junctions" "Nuclear membrane, Cytokinetic bridge, Cytosol" "CAB010416: , HPA034853: " "potential prognostic favorable (4.77e-5)" "unprognostic (1.52e-1)" "unprognostic (6.85e-2)" "unprognostic (1.92e-2)" "unprognostic (4.54e-2)" "unprognostic (3.26e-1)" "unprognostic (3.03e-1)" "unprognostic (5.15e-3)" "unprognostic (3.86e-3)" "unprognostic (4.42e-2)" "unprognostic (1.87e-1)" "unprognostic (7.47e-2)" "unprognostic (5.05e-2)" "unprognostic (9.16e-2)" "potential prognostic favorable (1.51e-5)" "unprognostic (3.62e-1)" "unprognostic (3.31e-2)" "unprognostic (3.55e-1)" "unprognostic (2.64e-2)" "unprognostic (1.24e-2)" "unprognostic (3.87e-1)" "unprognostic (4.23e-3)" "potential prognostic unfavorable (1.56e-4)" "unprognostic (1.54e-1)" "unprognostic (3.67e-2)" "unprognostic (7.24e-3)" "unprognostic (1.70e-1)" "unprognostic (5.01e-2)" "unprognostic (1.59e-1)" "potential prognostic favorable (6.81e-4)" "unprognostic (1.51e-1)" TIAM2 STEF ENSG00000146426 "TIAM Rac1 associated GEF 2" Q8IVF5 6 154832697-155257723 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.9;testis: 12.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 552.7;Late spermatids: 479.3;Myonuclei: 418.5;Pituitary stem cells: 361.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 6.4;non-classical monocyte: 9.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "olfactory bulb: 50.7" "HPA011134, HPA013903" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" No No "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 7: Non-specific - Transcription" 9 "Nucleoplasm, Nucleoli fibrillar center" Cytosol "HPA011134: , HPA013903: " "unprognostic (2.02e-1)" "unprognostic (4.39e-2)" "unprognostic (8.52e-2)" "unprognostic (1.40e-1)" "unprognostic (1.22e-3)" "unprognostic (4.67e-2)" "unprognostic (6.12e-2)" "unprognostic (2.89e-1)" "unprognostic (2.37e-1)" "unprognostic (1.39e-2)" "unprognostic (1.36e-1)" "unprognostic (1.43e-2)" "unprognostic (1.15e-1)" "unprognostic (6.77e-3)" "unprognostic (2.25e-1)" "unprognostic (6.40e-3)" "unprognostic (8.32e-2)" "unprognostic (1.47e-1)" "unprognostic (1.50e-2)" "unprognostic (3.31e-2)" TICAM1 "MGC35334, PRVTIRB, TICAM-1, TRIF" ENSG00000127666 "TIR domain containing adaptor molecule 1" Q8IUC6 19 4815932-4831712 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Antiviral defense, Apoptosis, Host-virus interaction, Immunity, Inflammatory response, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 44.2" "Cell type enhanced" "Detected in many" "Colonocytes: 262.2;Endometrial glandular cells: 128.4;Enterocytes: 333.7;Esophageal apical cells: 404.5;Ocular epithelial cells: 183.5;Urothelial cells: 141.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042460, HPA055421" Approved Uncertain "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 23: Non-specific - Transcription" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 20 "Nucleoplasm, Nucleoli" "Plasma membrane" "HPA042460: , HPA055421: " "unprognostic (1.39e-2)" "unprognostic (2.35e-2)" "unprognostic (1.03e-1)" "unprognostic (2.10e-2)" "unprognostic (1.68e-1)" "unprognostic (6.14e-3)" "unprognostic (1.47e-1)" "unprognostic (1.05e-2)" "unprognostic (1.18e-1)" "unprognostic (3.87e-2)" "potential prognostic favorable (3.24e-5)" "unprognostic (6.04e-2)" "unprognostic (2.64e-2)" "unprognostic (6.29e-2)" "unprognostic (1.12e-1)" "potential prognostic unfavorable (2.44e-4)" "unprognostic (6.69e-3)" "unprognostic (5.36e-2)" "unprognostic (1.11e-1)" "unprognostic (5.09e-2)" "unprognostic (1.85e-1)" "unprognostic (7.10e-2)" "unprognostic (2.45e-2)" "unprognostic (7.69e-2)" "unprognostic (6.06e-3)" "unprognostic (1.44e-3)" "unprognostic (7.84e-2)" "unprognostic (2.00e-2)" "unprognostic (5.03e-2)" "unprognostic (2.30e-2)" "unprognostic (2.20e-1)" TICAM2 "TICAM-2, TIRP, TRAM" ENSG00000243414 "TIR domain containing adaptor molecule 2" Q86XR7 5 115578496-115602479 "Predicted intracellular proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 11.6;Bergmann glia: 11.4;Brain excitatory neurons: 8.4;Brain inhibitory neurons: 10.0;Choroid plexus epithelial cells: 13.7;Ependymal cells: 6.5;Microglia: 31.2;Oligodendrocyte progenitor cells: 11.9;Oligodendrocytes: 12.5;Other brain neurons: 10.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Prostate - Fibroblasts, Stomach - Fibroblasts" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 5: Spleen - Immune response" "Cluster 19: Astrocytes - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 22: Non-specific - Basic cellular functions" 13 "unprognostic (9.36e-2)" "unprognostic (1.89e-1)" "unprognostic (4.53e-3)" "unprognostic (6.51e-3)" "unprognostic (1.98e-3)" "unprognostic (1.79e-3)" "unprognostic (4.20e-3)" "unprognostic (9.33e-3)" "validated prognostic unfavorable (1.37e-4)" "validated prognostic unfavorable (3.07e-5)" "unprognostic (3.02e-1)" "unprognostic (7.19e-2)" "unprognostic (5.95e-2)" "unprognostic (2.62e-2)" "unprognostic (4.10e-2)" "unprognostic (2.13e-1)" "unprognostic (4.13e-1)" "unprognostic (2.83e-2)" "unprognostic (3.14e-2)" "unprognostic (2.89e-1)" "unprognostic (2.33e-3)" "unprognostic (6.58e-2)" "unprognostic (3.95e-1)" "unprognostic (1.62e-1)" "unprognostic (6.07e-2)" "unprognostic (2.70e-2)" "unprognostic (1.10e-2)" "unprognostic (6.04e-2)" TICRR "C15orf42, FLJ41618, MGC45866, SLD3, Treslin" ENSG00000140534 "TOPBP1 interacting checkpoint and replication regulator" Q7Z2Z1 15 89575469-89631056 "Essential proteins, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 3.2;esophagus: 4.0;lymphoid tissue: 3.9" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 10.8;Cardiomyocytes: 9.3;Differentiating spermatogonia: 10.5;Early primary spermatocytes: 15.0;Epicardial cells: 15.9;Erythrocyte progenitors: 24.1;Esophageal basal cells: 16.3;Extravillous trophoblasts: 11.4;Megakaryocyte progenitors: 20.2;Monocyte progenitors: 34.5;Neutrophil progenitors: 14.2" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046746, HPA049454" Supported Nucleoplasm NA Yes "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 12: Non-specific - Vasculature" "Cluster 58: Non-specific - Nuclear processes" "Cluster 27: Non-specific - Cell proliferation" 9 Nucleoplasm "HPA046746: , HPA049454: " "unprognostic (2.13e-2)" "unprognostic (2.69e-2)" "unprognostic (1.63e-2)" "unprognostic (2.97e-1)" "unprognostic (2.61e-2)" "unprognostic (2.20e-1)" "unprognostic (2.36e-2)" "unprognostic (3.12e-1)" "validated prognostic unfavorable (1.80e-4)" "validated prognostic unfavorable (8.13e-5)" "unprognostic (1.23e-1)" "unprognostic (1.07e-3)" "unprognostic (2.65e-1)" "unprognostic (7.39e-3)" "unprognostic (1.83e-3)" "unprognostic (9.16e-2)" "unprognostic (1.45e-1)" "unprognostic (1.82e-3)" "unprognostic (3.09e-2)" "unprognostic (7.50e-2)" "unprognostic (4.99e-2)" TIE1 "JTK14, TIE" ENSG00000066056 "Tyrosine kinase with immunoglobulin like and EGF like domains 1" P35590 1 43300982-43323108 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 6 "Lymphatic endothelial cells: 206.8;Vascular endothelial cells: 179.2" "Cell type enriched" "Detected in some" 22 "endothelial cell: 263.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 24 "basophil: 2.2;NK-cell: 2.5" "Group enriched" "Detected in many" 24 "granulocytes: 2.2;NK-cells: 2.5" "Group enriched" "Detected in some" 5 "Leukemia: 14.3;ovarian cancer: 18.9;Sarcoma: 23.2;thyroid cancer: 28.7" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells, Spleen - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" Receptor NA NA 21000000 "Cluster 15: NK-cells - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 7 "unprognostic (2.93e-1)" "unprognostic (1.77e-1)" "unprognostic (4.58e-3)" "unprognostic (1.94e-1)" "unprognostic (1.69e-2)" "unprognostic (4.25e-2)" "unprognostic (8.04e-2)" "unprognostic (1.97e-1)" "unprognostic (2.04e-3)" "unprognostic (9.31e-2)" "validated prognostic favorable (2.32e-5)" "validated prognostic favorable (3.50e-5)" "potential prognostic unfavorable (2.02e-4)" "unprognostic (2.01e-2)" "potential prognostic favorable (1.31e-4)" "unprognostic (2.36e-1)" "unprognostic (7.94e-2)" "unprognostic (1.15e-3)" "unprognostic (6.49e-2)" "unprognostic (3.45e-2)" "unprognostic (2.53e-1)" "unprognostic (4.29e-2)" "unprognostic (3.20e-1)" "unprognostic (2.04e-1)" "unprognostic (1.06e-2)" "unprognostic (3.91e-2)" "unprognostic (1.86e-1)" "unprognostic (5.48e-3)" "unprognostic (2.41e-1)" "unprognostic (4.53e-3)" "unprognostic (1.30e-1)" TIFA "MGC20791, T2BP, T6BP, TIFAA" ENSG00000145365 "TRAF interacting protein with forkhead associated domain" Q96CG3 4 112272968-112285955 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal basal cells: 73.6;Esophageal apical cells: 127.5;Pancreatic acinar cells: 131.3;Plasma cells: 121.2;Syncytiotrophoblasts: 120.6" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 13.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "lymphoma: 112.1;Myeloma: 70.3" "Stomach - Chief cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045889 Approved Approved Nucleoplasm,Nucleoli,Cytosol NA Yes "Cluster 43: Non-specific - Transcription & Translation" "Cluster 8: Pancreas - Proteolysis" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 33 "Nucleoplasm, Nucleoli" Cytosol "HPA045889: " "unprognostic (7.99e-2)" "unprognostic (5.04e-2)" "unprognostic (2.12e-1)" "unprognostic (1.46e-1)" "unprognostic (3.73e-3)" "unprognostic (6.37e-3)" "unprognostic (1.32e-1)" "unprognostic (3.29e-2)" "unprognostic (5.23e-3)" "unprognostic (2.96e-3)" "potential prognostic favorable (7.50e-6)" "unprognostic (1.38e-2)" "unprognostic (2.18e-1)" "unprognostic (1.73e-1)" "unprognostic (4.23e-2)" "unprognostic (2.66e-1)" "unprognostic (4.48e-3)" "unprognostic (1.85e-1)" "unprognostic (3.09e-2)" "unprognostic (2.46e-1)" "unprognostic (4.28e-1)" "potential prognostic unfavorable (8.32e-4)" "unprognostic (4.01e-3)" "unprognostic (1.92e-1)" "unprognostic (4.19e-2)" "unprognostic (1.88e-1)" "unprognostic (5.19e-2)" "unprognostic (7.56e-2)" "unprognostic (1.25e-1)" "unprognostic (7.73e-2)" "unprognostic (1.25e-1)" TIFAB ENSG00000255833 "TIFA inhibitor" Q6ZNK6 5 135444226-135452351 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 5.3" "Group enriched" "Detected in some" 4 "cDC: 26.8;Late spermatids: 16.0;pDCs: 30.2" "Cancer enhanced" "Detected in single" "Testicular Germ Cell Tumor (TCGA): 2.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "myeloid DC: 4.5;plasmacytoid DC: 13.9" "Lineage enriched" "Detected in many" 11 "dendritic cells: 13.9" "Cancer enriched" "Detected in single" 38 "Leukemia: 3.8" "Lung - T-cells, Spleen - T-cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA049372 Uncertain NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 82: Dendritic cells - Antigen presentation" 2 "HPA049372: " "unprognostic (2.92e-2)" "unprognostic (8.87e-2)" "unprognostic (1.22e-1)" "unprognostic (1.01e-2)" TIGAR C12orf5 ENSG00000078237 "TP53 induced glycolysis regulatory phosphatase" Q9NQ88 12 4307763-4360028 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Autophagy" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 7 "Distal convoluted tubule cells: 13.6;Loop of henle epithelial cells: 17.8;Papillary tip epithelial cells: 25.0;Podocytes: 13.7;Proximal tubule cells: 15.7;Renal collecting duct intercalated cells: 25.4;Renal collecting duct principal cells: 31.4;Renal connecting tubule cells: 22.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "testis cancer: 20.2" "Pituitary gland - Corticotropes, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034010, HPA040354, HPA044111" Approved Supported Cytosol NA NA 15000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 34: Testis cancer - Unknown function" "Cluster 105: Non-specific - Mixed function" 11 Cytosol "CAB034010: , HPA040354: , HPA044111: " "unprognostic (7.88e-3)" "unprognostic (3.58e-3)" "unprognostic (1.94e-1)" "unprognostic (1.40e-1)" "unprognostic (2.31e-3)" "unprognostic (3.46e-1)" "unprognostic (5.86e-2)" "unprognostic (2.38e-1)" "unprognostic (3.77e-1)" "unprognostic (1.94e-1)" "unprognostic (1.34e-1)" "unprognostic (3.52e-1)" "unprognostic (1.56e-1)" "unprognostic (8.68e-2)" "unprognostic (5.58e-2)" "unprognostic (2.15e-1)" "unprognostic (2.97e-2)" "unprognostic (6.41e-2)" "unprognostic (1.10e-1)" "unprognostic (1.40e-1)" "unprognostic (1.39e-1)" "unprognostic (2.52e-1)" "unprognostic (2.39e-1)" "unprognostic (2.05e-2)" "unprognostic (1.53e-2)" "unprognostic (1.94e-1)" "unprognostic (6.23e-2)" "unprognostic (1.70e-1)" TIGD1 EEYORE ENSG00000221944 "Tigger transposable element derived 1" Q96MW7 2 232543883-232550557 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Myonuclei: 92.1;Thymic myoid cells: 35.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041717 Approved Approved "Nucleoplasm,Nucleoli rim,Nuclear bodies,Mitotic chromosome" Yes No "Cluster 21: Neutrophils - Unknown function" "Cluster 40: Non-specific - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 56: Non-specific - Sensory perception" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 4 "Nucleoli rim, Mitotic chromosome" "Nucleoplasm, Nuclear bodies" "HPA041717: " "unprognostic (1.64e-3)" "unprognostic (6.27e-2)" "unprognostic (1.23e-1)" "unprognostic (1.24e-1)" "potential prognostic unfavorable (2.54e-5)" "unprognostic (5.70e-2)" "unprognostic (5.17e-3)" "unprognostic (6.36e-2)" "unprognostic (1.91e-1)" "unprognostic (8.67e-3)" "potential prognostic unfavorable (1.72e-5)" "unprognostic (2.82e-1)" "unprognostic (1.96e-1)" "potential prognostic unfavorable (8.83e-4)" "unprognostic (8.21e-2)" "unprognostic (1.30e-1)" "unprognostic (4.22e-2)" "unprognostic (2.28e-2)" "potential prognostic favorable (2.46e-5)" "unprognostic (4.08e-2)" "unprognostic (9.84e-2)" "unprognostic (9.82e-2)" "unprognostic (5.66e-3)" "unprognostic (2.90e-2)" "unprognostic (1.17e-2)" "unprognostic (1.47e-2)" "unprognostic (2.97e-2)" "unprognostic (3.00e-1)" "unprognostic (2.21e-2)" "unprognostic (8.90e-2)" "unprognostic (2.14e-1)" TIGD2 ENSG00000180346 "Tigger transposable element derived 2" Q4W5G0 4 89111533-89114901 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 20.7" "Cell type enhanced" "Detected in many" "Breast lactating cells: 18.9;Cytotrophoblasts: 18.7;Hepatocytes: 23.7;Oocytes: 18.4;Syncytiotrophoblasts: 49.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 11.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 11.7" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054844, HPA071168" Uncertain Approved "Nuclear bodies" NA NA "Cluster 32: Basophils - Transcription" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 25: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" "Nuclear bodies" "HPA054844: , HPA071168: " "unprognostic (8.75e-2)" "unprognostic (1.63e-1)" "unprognostic (2.31e-1)" "unprognostic (2.57e-1)" "unprognostic (5.70e-3)" "unprognostic (5.74e-3)" "unprognostic (2.95e-1)" "unprognostic (2.95e-2)" "unprognostic (6.22e-2)" "unprognostic (3.15e-3)" "potential prognostic favorable (3.13e-5)" "unprognostic (1.44e-2)" "unprognostic (6.49e-3)" "unprognostic (3.04e-1)" "unprognostic (5.03e-3)" "unprognostic (1.28e-1)" "unprognostic (1.05e-1)" "unprognostic (2.28e-2)" "unprognostic (2.20e-3)" "unprognostic (2.17e-2)" "unprognostic (5.26e-2)" "unprognostic (1.17e-2)" "unprognostic (1.92e-1)" "unprognostic (6.25e-2)" "potential prognostic favorable (4.47e-4)" "unprognostic (2.25e-1)" "unprognostic (8.84e-2)" "unprognostic (4.25e-1)" "unprognostic (2.59e-1)" "unprognostic (2.36e-1)" "unprognostic (6.47e-3)" TIGD3 ENSG00000173825 "Tigger transposable element derived 3" Q6B0B8 11 65354751-65357613 "Essential proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.0;testis: 4.8" "Cell type enriched" "Detected in some" 4 "Early primary spermatocytes: 42.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 8 "basophil: 7.8;eosinophil: 10.9;neutrophil: 17.5" "Lineage enriched" "Detected in many" 11 "granulocytes: 17.5" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" HPA040016 Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 67: Testis - Mixed function" "Cluster 2: Neurons - Nucleosome" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 3: Early primary spermatocytes - Early meiosis" 3 "Nucleoplasm, Nuclear membrane" "HPA040016: " "unprognostic (8.91e-3)" "unprognostic (4.78e-2)" "potential prognostic favorable (3.49e-4)" "unprognostic (1.51e-2)" "unprognostic (1.09e-3)" "unprognostic (5.42e-3)" TIGD4 ENSG00000169989 "Tigger transposable element derived 4" Q8IY51 4 152769354-152779730 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "retina: 20.4" "Cell type enhanced" "Detected in many" "Early spermatids: 107.3;Ependymal cells: 53.4;Late primary spermatocytes: 115.5;Microglia: 43.7;Pituitary stem cells: 38.2;Respiratory ciliated cells: 34.2;Rod photoreceptor cells: 65.7" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 49.7;ependymal cell: 58.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA035649, HPA073768" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 42: Retina - Visual perception" "Cluster 17: Choroid plexus - Cilium" "Cluster 20: Myeloma - Immune response" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 2 Cytosol Nucleoplasm "HPA035649: , HPA073768: " "unprognostic (9.51e-2)" "unprognostic (9.31e-2)" "unprognostic (4.07e-2)" "unprognostic (2.44e-1)" "unprognostic (1.69e-2)" "unprognostic (2.45e-1)" TIGD5 FLJ14926 ENSG00000179886 "Tigger transposable element derived 5" Q53EQ6 8 143597831-143603224 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 2.8;Bergmann glia: 3.9;Brain excitatory neurons: 3.2;Brain inhibitory neurons: 2.7;Choroid plexus epithelial cells: 2.3;Distal convoluted tubule cells: 2.3;Ependymal cells: 3.6;Loop of henle epithelial cells: 2.8;Microglia: 2.3;Oligodendrocyte progenitor cells: 4.7;Oligodendrocytes: 3.5;Other brain neurons: 4.0;Papillary tip epithelial cells: 2.9;Podocytes: 2.6;Proximal tubule cells: 2.5;Renal collecting duct intercalated cells: 2.4;Renal collecting duct principal cells: 2.9;Renal connecting tubule cells: 3.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (granular), Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" 7 "unprognostic (1.64e-1)" "unprognostic (2.36e-1)" "unprognostic (9.22e-2)" "unprognostic (6.32e-2)" "unprognostic (3.38e-1)" "unprognostic (6.13e-2)" "unprognostic (1.59e-1)" "unprognostic (5.79e-3)" "unprognostic (5.84e-2)" "unprognostic (6.39e-2)" "unprognostic (1.28e-1)" "unprognostic (2.64e-2)" "unprognostic (1.91e-2)" "unprognostic (7.51e-2)" "unprognostic (8.73e-2)" "unprognostic (7.81e-2)" "unprognostic (5.53e-2)" "unprognostic (2.07e-1)" "unprognostic (1.62e-2)" "unprognostic (2.35e-1)" "unprognostic (2.12e-2)" "unprognostic (1.08e-1)" "unprognostic (4.40e-2)" "unprognostic (2.84e-2)" TIGD6 DKFZp761E2110 ENSG00000164296 "Tigger transposable element derived 6" Q17RP2 5 149993118-150000654 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 21.3;Early primary spermatocytes: 19.2;Epididymal principal cells: 16.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells" "HPA044599, HPA057538" Uncertain Approved "Nucleoplasm,Vesicles,Actin filaments" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 55: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" Nucleoplasm "Vesicles, Actin filaments" "HPA044599: , HPA057538: " "unprognostic (6.13e-2)" "unprognostic (1.46e-1)" "unprognostic (5.21e-2)" "unprognostic (1.64e-3)" "unprognostic (3.17e-2)" "unprognostic (2.86e-1)" "unprognostic (7.25e-2)" "unprognostic (5.11e-2)" "unprognostic (1.47e-2)" "unprognostic (2.56e-3)" "potential prognostic favorable (1.19e-5)" "unprognostic (4.92e-2)" "unprognostic (3.39e-1)" "unprognostic (3.78e-3)" "unprognostic (3.88e-1)" "unprognostic (1.01e-1)" "unprognostic (1.47e-1)" "unprognostic (1.43e-1)" "unprognostic (1.79e-1)" "unprognostic (3.22e-1)" "unprognostic (2.57e-1)" "unprognostic (1.89e-3)" "unprognostic (2.94e-2)" "unprognostic (3.56e-3)" "potential prognostic favorable (3.09e-4)" "unprognostic (1.26e-1)" "unprognostic (5.29e-2)" "unprognostic (1.09e-3)" "unprognostic (3.18e-1)" "unprognostic (2.79e-2)" "unprognostic (1.44e-1)" TIGD7 Sancho ENSG00000140993 "Tigger transposable element derived 7" Q6NT04 16 3298808-3305729 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 66.1;Choroid plexus epithelial cells: 46.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA041357, HPA041474" Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 21: Testis - Mixed function" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 1 "Plasma membrane, Cytosol" "HPA041357: , HPA041474: " "unprognostic (1.52e-1)" "unprognostic (4.12e-3)" "unprognostic (3.88e-1)" "unprognostic (3.04e-2)" "potential prognostic favorable (2.32e-4)" "unprognostic (1.35e-1)" "unprognostic (2.23e-2)" "unprognostic (5.54e-2)" "unprognostic (2.37e-1)" "unprognostic (1.05e-3)" "unprognostic (4.10e-3)" "unprognostic (4.33e-2)" "unprognostic (5.97e-3)" "unprognostic (5.06e-2)" "unprognostic (1.90e-2)" "unprognostic (3.31e-2)" "unprognostic (3.01e-1)" "unprognostic (8.90e-2)" "unprognostic (1.60e-1)" "unprognostic (9.66e-2)" "unprognostic (5.98e-3)" "unprognostic (2.56e-3)" "unprognostic (9.78e-2)" "unprognostic (1.76e-1)" "unprognostic (2.44e-2)" "unprognostic (5.64e-2)" "unprognostic (4.73e-1)" "unprognostic (1.45e-3)" "unprognostic (5.38e-2)" TIGIT "DKFZp667A205, FLJ39873, VSIG9, VSTM3" ENSG00000181847 "T cell immunoreceptor with Ig and ITIM domains" Q495A1 3 114276913-114310288 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 36.1" "Group enriched" "Detected in some" 5 "NK-cells: 59.4;T-cells: 95.9" "Cell type enriched" "Detected in some" 10 "leukocyte: 43.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 196.2" "Lineage enriched" "Detected in many" 11 "T-cells: 196.2" "Group enriched" "Detected in some" 7 "lymphoma: 5.2;Myeloma: 2.0" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Minor Salivary Gland - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Skin - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" 12 "unprognostic (1.13e-2)" "unprognostic (2.29e-2)" "unprognostic (3.68e-2)" "potential prognostic favorable (6.67e-5)" "unprognostic (6.26e-2)" "unprognostic (8.06e-2)" "unprognostic (2.42e-1)" "potential prognostic favorable (8.85e-6)" "unprognostic (5.72e-3)" "unprognostic (2.00e-1)" "potential prognostic unfavorable (2.38e-4)" "unprognostic (2.25e-1)" "unprognostic (2.17e-1)" "unprognostic (2.70e-2)" "unprognostic (3.36e-1)" "unprognostic (6.45e-2)" "unprognostic (2.52e-1)" "unprognostic (5.17e-3)" "unprognostic (1.51e-2)" "unprognostic (8.27e-2)" "potential prognostic unfavorable (6.67e-4)" "unprognostic (8.24e-2)" "unprognostic (6.33e-2)" "unprognostic (4.89e-3)" "unprognostic (8.61e-2)" "unprognostic (1.37e-1)" "unprognostic (2.39e-1)" "unprognostic (1.20e-2)" "unprognostic (2.92e-2)" TIMD4 TIM4 ENSG00000145850 "T cell immunoglobulin and mucin domain containing 4" Q96H15 5 156919292-156963226 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "lymphoid tissue: 51.7;testis: 137.3" "Cell type enhanced" "Detected in some" "Early spermatids: 1393.4;Kupffer cells: 349.5;Late primary spermatocytes: 655.7;Late spermatids: 2823.6" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 5.4" "Cancer enriched" "Detected in many" 5 "Kidney Chromophobe (TCGA): 49.8" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 5 "memory CD4 T-cell: 1.3;memory CD8 T-cell: 2.5;naive CD4 T-cell: 1.6;naive CD8 T-cell: 1.6;T-reg: 4.0" "Lineage enriched" "Detected in single" 18 "T-cells: 4.0" "Group enriched" "Detected in some" 4 "Kidney cancer: 9.0;lymphoma: 4.2;Myeloma: 10.3" "Adipose subcutaneous - Macrophages, Liver - Kupffer cells, Spleen - Macrophages, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015625, CAB026027" Approved Approved "Plasma membrane" "Intracellular and membrane" "No annotated function" NA NA 4000000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 39: Testis - Nuclear processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 2 "Plasma membrane" "CAB026027: , HPA015625: " "unprognostic (4.77e-1)" "unprognostic (1.81e-1)" "unprognostic (5.92e-3)" "unprognostic (1.18e-1)" "unprognostic (2.81e-2)" "unprognostic (5.80e-2)" "unprognostic (1.69e-1)" "unprognostic (1.62e-1)" "unprognostic (5.86e-2)" "unprognostic (3.22e-1)" "unprognostic (5.45e-2)" "unprognostic (3.69e-1)" "unprognostic (8.79e-2)" "potential prognostic unfavorable (5.62e-7)" "unprognostic (6.51e-2)" "unprognostic (2.28e-1)" "unprognostic (5.56e-2)" TIMELESS "hTIM, TIM, TIM1" ENSG00000111602 "Timeless circadian regulator" Q9UNS1 12 56416363-56449426 "Disease related genes, Essential proteins, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Cell division, DNA damage, DNA repair, Mitosis, Transcription, Transcription regulation" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 33.8;Erythrocyte progenitors: 43.9;Gastric progenitor cells: 29.5;Gonadotrophs: 31.9;Megakaryocyte progenitors: 39.9;Monocyte progenitors: 44.0;Retinal bipolar cells: 54.5;Undifferentiated spermatogonia: 28.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA060655 Enhanced Supported Nucleoplasm No No "Cluster 14: Non-specific - Unknown function" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 17 Nucleoplasm "HPA060655: " "unprognostic (1.50e-1)" "unprognostic (1.92e-2)" "unprognostic (3.71e-2)" "unprognostic (1.78e-1)" "unprognostic (2.00e-2)" "unprognostic (1.86e-1)" "unprognostic (3.56e-1)" "unprognostic (2.93e-1)" "unprognostic (8.61e-2)" "potential prognostic unfavorable (5.63e-5)" "unprognostic (5.47e-3)" "unprognostic (6.76e-2)" "unprognostic (1.09e-1)" "validated prognostic unfavorable (7.00e-4)" "validated prognostic unfavorable (2.71e-4)" "potential prognostic unfavorable (6.19e-4)" "unprognostic (4.13e-3)" "unprognostic (1.14e-1)" "unprognostic (1.64e-2)" "unprognostic (5.99e-2)" "unprognostic (3.86e-2)" "unprognostic (7.23e-2)" "unprognostic (9.53e-3)" "unprognostic (8.42e-2)" "unprognostic (7.58e-3)" "unprognostic (5.01e-2)" "potential prognostic unfavorable (4.55e-4)" "unprognostic (5.56e-2)" "unprognostic (3.34e-1)" "unprognostic (7.02e-2)" "unprognostic (2.25e-1)" TIMM10 "TIM10, TIM10A, TIMM10A" ENSG00000134809 "Translocase of inner mitochondrial membrane 10" P62072 11 57528464-57530803 "Essential proteins, Predicted intracellular proteins" "Protein transport, Translocation, Transport" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 231.8;Late spermatids: 389.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039946 Supported Enhanced Mitochondria NA NA 4300 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 46 Mitochondria "HPA039946: " "unprognostic (5.36e-2)" "unprognostic (5.86e-3)" "unprognostic (5.21e-2)" "unprognostic (1.45e-1)" "unprognostic (2.12e-1)" "unprognostic (5.93e-2)" "unprognostic (8.93e-2)" "unprognostic (2.31e-1)" "unprognostic (6.29e-3)" "potential prognostic unfavorable (3.36e-4)" "potential prognostic favorable (1.89e-5)" "unprognostic (1.12e-1)" "unprognostic (5.43e-2)" "unprognostic (1.24e-1)" "unprognostic (5.84e-3)" "unprognostic (1.72e-2)" "unprognostic (4.71e-3)" "unprognostic (1.45e-2)" "unprognostic (2.34e-1)" "unprognostic (2.57e-3)" "unprognostic (8.74e-2)" "unprognostic (1.35e-1)" "unprognostic (1.54e-1)" "unprognostic (1.79e-1)" "unprognostic (3.09e-1)" "unprognostic (1.48e-1)" "unprognostic (1.18e-1)" "unprognostic (8.65e-2)" "unprognostic (2.39e-1)" "unprognostic (1.03e-2)" "unprognostic (1.00e-1)" TIMM10B "FXC1, TIM10B, Tim9b" ENSG00000132286 "Translocase of inner mitochondrial membrane 10B" Q9Y5J6 11 6481501-6484681 "Predicted intracellular proteins" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 2.5;Early primary spermatocytes: 5.2;Early spermatids: 3.5;Epididymal principal cells: 2.4;Gastric progenitor cells: 2.6;Late primary spermatocytes: 3.2;Medullary thymic epithelial cells: 2.4;Syncytiotrophoblasts: 2.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Endothelial cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" HPA052265 Approved NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 24: Non-specific - Unknown function" "Cluster 8: Non-specific - Secretory pathway" 10 "HPA052265: " "unprognostic (2.39e-3)" "unprognostic (3.83e-2)" "potential prognostic unfavorable (2.16e-4)" "unprognostic (8.94e-2)" "unprognostic (4.01e-1)" "unprognostic (5.15e-2)" "potential prognostic unfavorable (5.84e-4)" "unprognostic (2.76e-2)" "unprognostic (1.08e-1)" "potential prognostic favorable (9.84e-7)" "unprognostic (1.52e-3)" "unprognostic (3.66e-3)" "potential prognostic unfavorable (6.46e-4)" "unprognostic (2.48e-3)" "unprognostic (5.23e-3)" "unprognostic (1.11e-2)" "unprognostic (1.65e-1)" "unprognostic (1.01e-1)" "unprognostic (2.12e-2)" "unprognostic (1.24e-1)" "unprognostic (9.25e-2)" "unprognostic (3.29e-1)" "unprognostic (1.74e-2)" "unprognostic (1.68e-1)" "unprognostic (1.14e-1)" "unprognostic (1.40e-1)" "unprognostic (3.69e-1)" "unprognostic (2.46e-1)" "unprognostic (3.83e-2)" TIMM13 "Tim13, TIMM13B" ENSG00000099800 "Translocase of inner mitochondrial membrane 13" Q9Y5L4 19 2425625-2427586 "Essential proteins, Predicted intracellular proteins" "Protein transport, Translocation, Transport" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 716.7;Esophageal suprabasal cells: 676.6;Hepatocytes: 489.6;Migrating cytotrophoblasts: 533.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048985 Uncertain Supported "Nucleoli fibrillar center,Mitochondria" NA NA 62000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 19 Mitochondria "Nucleoli fibrillar center" "HPA048985: " "unprognostic (4.92e-1)" "unprognostic (9.97e-3)" "unprognostic (1.90e-1)" "unprognostic (1.57e-1)" "unprognostic (2.24e-1)" "unprognostic (1.09e-1)" "unprognostic (1.69e-1)" "unprognostic (3.70e-1)" "unprognostic (8.87e-2)" "unprognostic (3.29e-1)" "unprognostic (2.08e-3)" "unprognostic (4.50e-1)" "unprognostic (2.63e-3)" "validated prognostic unfavorable (4.63e-4)" "validated prognostic unfavorable (8.36e-8)" "unprognostic (3.80e-2)" "unprognostic (8.71e-2)" "unprognostic (3.50e-2)" "unprognostic (7.56e-2)" "unprognostic (1.32e-1)" "unprognostic (3.86e-2)" "unprognostic (6.00e-3)" "unprognostic (7.26e-2)" "unprognostic (6.09e-2)" "unprognostic (1.54e-1)" "unprognostic (1.50e-2)" "unprognostic (9.06e-2)" "unprognostic (1.52e-1)" "unprognostic (4.88e-2)" "unprognostic (2.41e-1)" "unprognostic (2.62e-3)" TIMM17A "TIM17, TIM17A" ENSG00000134375 "Translocase of inner mitochondrial membrane 17A" Q99595 1 201955503-201970664 "Cancer-related genes, Predicted membrane proteins" "Protein transport, Translocation, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epididymal principal cells: 214.9;Extravillous trophoblasts: 243.3;Syncytiotrophoblasts: 371.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010083 Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 23: Choroid plexus - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 1 "Nucleoplasm, Mitochondria" "HPA010083: " "unprognostic (1.38e-1)" "unprognostic (3.00e-3)" "unprognostic (3.73e-1)" "unprognostic (2.57e-1)" "unprognostic (5.52e-2)" "unprognostic (8.66e-2)" "unprognostic (4.50e-1)" "unprognostic (2.06e-2)" "unprognostic (6.55e-3)" "unprognostic (1.73e-3)" "unprognostic (3.31e-3)" "unprognostic (1.51e-2)" "unprognostic (1.34e-1)" "unprognostic (1.67e-2)" "unprognostic (2.37e-1)" "potential prognostic unfavorable (3.70e-4)" "unprognostic (1.56e-1)" "unprognostic (1.49e-1)" "unprognostic (1.96e-1)" "unprognostic (9.43e-2)" "unprognostic (9.60e-3)" "unprognostic (1.01e-2)" "unprognostic (4.89e-2)" "potential prognostic unfavorable (6.67e-4)" "unprognostic (2.37e-1)" "unprognostic (2.10e-1)" "unprognostic (6.37e-2)" "unprognostic (8.55e-2)" "unprognostic (2.81e-1)" "unprognostic (3.25e-2)" "unprognostic (9.94e-2)" TIMM17B "DXS9822, JM3" ENSG00000126768 "Translocase of inner mitochondrial membrane 17B" O60830 X 48893447-48898143 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 149.0;Hofbauer cells: 149.4;Oocytes: 276.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029093 Approved Approved Microtubules,Mitochondria NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 27: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 97: Non-specific - Cellular respiration" 22 Microtubules Mitochondria "HPA029093: " "unprognostic (3.93e-1)" "unprognostic (6.04e-3)" "unprognostic (2.23e-1)" "unprognostic (1.33e-2)" "unprognostic (8.88e-2)" "unprognostic (6.25e-2)" "unprognostic (8.22e-2)" "unprognostic (1.42e-2)" "unprognostic (5.88e-2)" "unprognostic (5.18e-3)" "unprognostic (6.91e-2)" "unprognostic (5.39e-2)" "unprognostic (2.62e-3)" "unprognostic (2.48e-3)" "potential prognostic unfavorable (4.39e-5)" "unprognostic (2.51e-2)" "unprognostic (1.25e-1)" "unprognostic (5.93e-2)" "unprognostic (1.61e-1)" "unprognostic (9.47e-2)" "unprognostic (1.61e-1)" "unprognostic (1.15e-1)" "unprognostic (1.67e-1)" "unprognostic (3.48e-1)" "unprognostic (1.37e-1)" "unprognostic (3.99e-1)" "unprognostic (1.60e-1)" "unprognostic (1.47e-1)" "unprognostic (2.26e-2)" "unprognostic (5.45e-2)" "unprognostic (1.40e-1)" TIMM21 "C18orf55, HSPC154, TIM21" ENSG00000075336 "Translocase of inner mitochondrial membrane 21" Q9BVV7 18 74148523-74160531 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Minor Salivary Gland - Endothelial cells, Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010587, HPA051543" Uncertain NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 31: Non-specific - Transcription" "Cluster 13: Non-specific - Mixed function" "Cluster 97: Non-specific - Cellular respiration" 2 "HPA010587: , HPA051543: " "unprognostic (7.47e-2)" "unprognostic (1.81e-1)" "unprognostic (2.37e-1)" "unprognostic (4.14e-2)" "unprognostic (7.06e-2)" "unprognostic (1.56e-1)" "unprognostic (9.22e-2)" "unprognostic (1.71e-1)" "unprognostic (5.37e-2)" "potential prognostic favorable (8.43e-4)" "unprognostic (3.46e-2)" "potential prognostic favorable (5.55e-6)" "potential prognostic unfavorable (1.32e-5)" "unprognostic (6.24e-2)" "unprognostic (3.97e-1)" "potential prognostic favorable (3.09e-4)" "unprognostic (2.47e-2)" "unprognostic (6.52e-2)" "unprognostic (3.22e-1)" "unprognostic (4.13e-3)" "unprognostic (1.26e-1)" "unprognostic (3.20e-2)" "unprognostic (2.83e-1)" "unprognostic (1.63e-2)" "unprognostic (1.63e-2)" "unprognostic (1.44e-1)" "unprognostic (1.51e-1)" "unprognostic (1.26e-1)" "unprognostic (6.70e-2)" TIMM22 "TEX4, TIM22" ENSG00000177370 "Translocase of inner mitochondrial membrane 22" Q9Y584 17 997129-1003671 "Disease related genes, Essential proteins, Human disease related genes, Predicted membrane proteins" "Protein transport, Translocation, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Bergmann glia: 10.7;Brain excitatory neurons: 12.0;Brain inhibitory neurons: 11.0;Choroid plexus epithelial cells: 6.4;Distal convoluted tubule cells: 7.7;Ependymal cells: 7.1;Loop of henle epithelial cells: 8.5;Microglia: 9.2;Oligodendrocyte progenitor cells: 11.3;Other brain neurons: 14.2;Papillary tip epithelial cells: 8.4;Podocytes: 10.1;Proximal tubule cells: 7.1;Renal collecting duct intercalated cells: 7.9;Renal collecting duct principal cells: 10.2;Renal connecting tubule cells: 7.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 40 "basophil: 4.0" "Lineage enriched" "Detected in single" 40 "granulocytes: 4.0" "Cancer enhanced" "Detected in many" "testis cancer: 11.3" "Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045138 Uncertain NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 52: Non-specific - Cellular respiration" "Cluster 5: Non-specific - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 98: Neurons - Neurotransmission & signaling" 4 "HPA045138: " "unprognostic (3.82e-2)" "unprognostic (1.68e-1)" "unprognostic (1.07e-1)" "unprognostic (2.86e-1)" "unprognostic (1.24e-1)" "unprognostic (1.11e-1)" "unprognostic (9.09e-3)" "unprognostic (2.53e-2)" "unprognostic (1.17e-2)" "unprognostic (1.43e-1)" "unprognostic (3.37e-3)" "unprognostic (4.37e-3)" "unprognostic (2.65e-3)" "unprognostic (1.38e-3)" "unprognostic (6.66e-2)" "unprognostic (1.39e-1)" "unprognostic (3.06e-1)" "unprognostic (5.06e-2)" "unprognostic (1.10e-1)" "unprognostic (1.98e-1)" "unprognostic (4.24e-2)" "unprognostic (4.75e-3)" "unprognostic (6.69e-2)" "unprognostic (2.49e-1)" "unprognostic (3.23e-1)" "unprognostic (3.30e-1)" "unprognostic (6.17e-2)" "unprognostic (1.90e-1)" "unprognostic (1.47e-1)" "unprognostic (2.11e-1)" "unprognostic (6.08e-2)" TIMM23 TIM23 ENSG00000265354 "Translocase of inner mitochondrial membrane 23" O14925 10 45972489-46003742 "Essential proteins, Predicted membrane proteins" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 236.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" HPA031408 Approved Supported Mitochondria NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 52: Non-specific - Mitochondria" "Cluster 17: Non-specific - RNA processing" 22 Mitochondria "HPA031408: " "unprognostic (1.73e-2)" "potential prognostic unfavorable (8.68e-4)" "unprognostic (1.43e-1)" "unprognostic (2.73e-3)" "unprognostic (5.35e-2)" "unprognostic (4.59e-2)" "unprognostic (7.68e-3)" "unprognostic (1.11e-2)" "unprognostic (4.27e-2)" "unprognostic (1.03e-1)" "unprognostic (4.18e-1)" "potential prognostic unfavorable (2.17e-7)" "unprognostic (1.11e-1)" "unprognostic (1.12e-3)" "unprognostic (1.34e-2)" "unprognostic (1.44e-1)" "unprognostic (5.27e-2)" "unprognostic (1.47e-2)" "unprognostic (3.78e-3)" "unprognostic (3.75e-2)" "unprognostic (2.06e-1)" "unprognostic (2.04e-1)" "unprognostic (1.03e-1)" "unprognostic (1.94e-1)" "unprognostic (1.61e-1)" "unprognostic (8.68e-2)" "unprognostic (1.73e-1)" TIMM23B bA592B15.7 ENSG00000204152 "Translocase of inner mitochondrial membrane 23 homolog B" Q5SRD1 10 49942049-49974850 "Predicted membrane proteins" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Bergmann glia: 52.0;Brain excitatory neurons: 56.3;Brain inhibitory neurons: 53.0;Choroid plexus epithelial cells: 96.5;Distal convoluted tubule cells: 183.8;Loop of henle epithelial cells: 129.8;Microglia: 63.1;Oligodendrocytes: 51.6;Other brain neurons: 51.2;Papillary tip epithelial cells: 77.5;Podocytes: 123.9;Proximal tubule cells: 315.0;Renal collecting duct intercalated cells: 159.3;Renal collecting duct principal cells: 90.9;Renal connecting tubule cells: 184.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 105: Non-specific - Mixed function" "unprognostic (5.13e-2)" "unprognostic (3.55e-2)" "unprognostic (1.97e-2)" "unprognostic (7.06e-2)" "unprognostic (1.94e-1)" "unprognostic (1.95e-1)" "potential prognostic favorable (9.03e-5)" "unprognostic (1.78e-2)" "unprognostic (1.31e-1)" "unprognostic (1.98e-1)" "unprognostic (8.20e-3)" "unprognostic (3.41e-2)" "unprognostic (1.30e-1)" "unprognostic (2.23e-1)" "unprognostic (1.39e-1)" "unprognostic (2.32e-1)" "unprognostic (8.20e-2)" "unprognostic (2.72e-3)" "unprognostic (1.51e-1)" "unprognostic (2.58e-1)" "unprognostic (4.71e-2)" "unprognostic (1.04e-1)" "unprognostic (2.66e-1)" "unprognostic (1.01e-1)" "unprognostic (2.87e-1)" "unprognostic (1.60e-2)" "unprognostic (3.85e-1)" "unprognostic (1.98e-2)" "unprognostic (1.99e-1)" TIMM29 "C19orf52, TIM29" ENSG00000142444 "Translocase of inner mitochondrial membrane 29" Q9BSF4 19 10928811-10933535 "Essential proteins, Predicted intracellular proteins" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 124.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041858 Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 3: Early primary spermatocytes - Early meiosis" 11 Mitochondria Nucleoplasm "HPA041858: " "unprognostic (5.11e-2)" "unprognostic (9.52e-2)" "unprognostic (1.80e-1)" "unprognostic (3.24e-2)" "unprognostic (1.09e-1)" "unprognostic (3.59e-1)" "unprognostic (1.16e-2)" "unprognostic (9.23e-2)" "unprognostic (2.33e-1)" "unprognostic (1.18e-1)" "unprognostic (3.40e-1)" "unprognostic (5.23e-2)" "unprognostic (1.38e-2)" "unprognostic (3.13e-2)" "unprognostic (4.35e-2)" "unprognostic (8.79e-2)" "unprognostic (8.06e-2)" "unprognostic (9.76e-3)" "unprognostic (6.83e-2)" "unprognostic (1.38e-1)" "unprognostic (3.42e-1)" "unprognostic (1.05e-2)" "unprognostic (3.35e-2)" "unprognostic (8.59e-2)" "unprognostic (4.94e-2)" "potential prognostic favorable (9.24e-5)" "unprognostic (8.82e-2)" "unprognostic (1.26e-1)" "unprognostic (1.42e-1)" TIMM44 TIM44 ENSG00000104980 "Translocase of inner mitochondrial membrane 44" O43615 19 7926718-7943667 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043052, HPA073108" Supported Enhanced Mitochondria NA NA 3500 "Cluster 5: Non-specific - Cell proliferation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 97: Non-specific - Cellular respiration" 20 Mitochondria "HPA043052: , HPA073108: " "unprognostic (2.04e-2)" "unprognostic (3.00e-1)" "unprognostic (6.04e-2)" "unprognostic (4.24e-2)" "unprognostic (6.12e-2)" "unprognostic (6.86e-2)" "unprognostic (1.31e-1)" "unprognostic (7.12e-2)" "unprognostic (7.02e-2)" "potential prognostic unfavorable (1.35e-4)" "unprognostic (4.18e-2)" "unprognostic (1.05e-2)" "unprognostic (9.84e-3)" "validated prognostic unfavorable (3.01e-4)" "validated prognostic unfavorable (9.10e-4)" "unprognostic (8.79e-3)" "unprognostic (2.94e-2)" "unprognostic (3.90e-2)" "unprognostic (8.49e-2)" "unprognostic (6.42e-2)" "unprognostic (7.45e-2)" "unprognostic (5.49e-2)" "unprognostic (1.33e-3)" "unprognostic (1.61e-2)" "unprognostic (1.79e-1)" "unprognostic (1.39e-1)" "unprognostic (8.12e-2)" "unprognostic (1.51e-2)" "unprognostic (1.24e-2)" "unprognostic (9.18e-2)" "unprognostic (4.73e-2)" TIMM50 "TIM50, TIM50L" ENSG00000105197 "Translocase of inner mitochondrial membrane 50" Q3ZCQ8 19 39480412-39493785 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Translocation, Transport" RNA-binding "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Late spermatids: 1046.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048843, HPA056448" Enhanced Supported Nucleoplasm,Mitochondria NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cellular respiration" "Cluster 14: Neurons - Synaptic function" "Cluster 4: Non-specific - Transcription" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 25 "Nucleoplasm, Mitochondria" "HPA048843: , HPA056448: " "unprognostic (1.42e-1)" "unprognostic (3.44e-1)" "unprognostic (5.63e-2)" "unprognostic (3.07e-3)" "unprognostic (1.35e-3)" "unprognostic (1.86e-1)" "unprognostic (2.39e-2)" "unprognostic (1.60e-2)" "unprognostic (5.90e-2)" "unprognostic (4.33e-1)" "unprognostic (7.00e-3)" "unprognostic (5.47e-2)" "unprognostic (3.50e-2)" "unprognostic (1.50e-2)" "potential prognostic unfavorable (9.37e-4)" "unprognostic (5.36e-3)" "unprognostic (1.98e-1)" "unprognostic (2.04e-1)" "unprognostic (1.93e-1)" "unprognostic (1.88e-2)" "unprognostic (1.96e-1)" "unprognostic (1.08e-1)" "unprognostic (5.91e-2)" "unprognostic (6.91e-2)" "unprognostic (1.69e-2)" "unprognostic (6.04e-2)" "unprognostic (1.52e-1)" "unprognostic (1.08e-1)" "unprognostic (1.50e-1)" "unprognostic (2.79e-1)" "unprognostic (2.84e-1)" TIMM8A "DDP, DFN1, MTS" ENSG00000126953 "Translocase of inner mitochondrial membrane 8A" O60220 X 101345661-101348742 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Translocation, Transport" Chaperone "Deafness, Disease variant, Dystonia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 78.0;Cytotrophoblasts: 44.7;Esophageal basal cells: 62.9;Extravillous trophoblasts: 46.4;Gastric progenitor cells: 55.1;Hepatocytes: 80.5;Migrating cytotrophoblasts: 60.2;Oocytes: 41.4;Suprabasal keratinocytes: 62.6;Syncytiotrophoblasts: 48.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003628 Supported Supported Mitochondria NA NA 12000 "Cluster 18: Non-specific - Translation" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 26: Keratinocytes - Keratinization" 19 Mitochondria "HPA003628: " "unprognostic (6.50e-2)" "potential prognostic unfavorable (9.16e-5)" "unprognostic (7.73e-2)" "potential prognostic favorable (6.35e-5)" "unprognostic (1.58e-1)" "unprognostic (1.11e-1)" "unprognostic (5.07e-2)" "unprognostic (3.34e-1)" "potential prognostic unfavorable (5.22e-4)" "unprognostic (1.88e-1)" "potential prognostic favorable (1.20e-4)" "unprognostic (6.21e-2)" "unprognostic (3.69e-2)" "unprognostic (1.01e-2)" "unprognostic (2.64e-2)" "unprognostic (1.03e-2)" "potential prognostic unfavorable (3.61e-4)" "unprognostic (6.81e-2)" "unprognostic (2.32e-2)" "unprognostic (2.28e-3)" "unprognostic (1.53e-2)" "unprognostic (2.18e-3)" "unprognostic (1.14e-3)" "potential prognostic unfavorable (2.37e-4)" "unprognostic (2.70e-3)" "unprognostic (8.93e-2)" "unprognostic (7.94e-2)" "unprognostic (3.81e-2)" "unprognostic (1.69e-1)" "unprognostic (2.74e-1)" "unprognostic (3.46e-2)" TIMM8B "DDP2, FLJ21744, MGC102866, MGC117373, TIM8B" ENSG00000150779 "Translocase of inner mitochondrial membrane 8 homolog B" Q9Y5J9 11 112084800-112086798 "Predicted intracellular proteins" "Protein transport, Translocation, Transport" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 704.2;Esophageal basal cells: 412.2;Esophageal suprabasal cells: 761.3;Hepatocytes: 518.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041173 Approved NA NA 4000 "Cluster 29: Non-specific - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 24: Non-specific - Unknown function" "Cluster 85: Squamous epithelial cells - Keratinization" 6 "HPA041173: " "unprognostic (3.78e-2)" "unprognostic (6.89e-3)" "unprognostic (2.36e-2)" "potential prognostic favorable (1.33e-4)" "unprognostic (2.72e-3)" "unprognostic (5.08e-2)" "unprognostic (6.30e-2)" "unprognostic (2.69e-1)" "unprognostic (1.48e-1)" "unprognostic (2.48e-2)" "unprognostic (2.36e-2)" "unprognostic (1.20e-1)" "unprognostic (3.88e-2)" "unprognostic (9.59e-3)" "unprognostic (3.10e-2)" "unprognostic (8.73e-2)" "unprognostic (1.59e-1)" "unprognostic (1.67e-3)" "unprognostic (4.25e-2)" "potential prognostic favorable (9.55e-4)" "unprognostic (2.13e-1)" "unprognostic (1.19e-2)" "unprognostic (3.86e-2)" "unprognostic (7.17e-2)" "unprognostic (3.40e-1)" "unprognostic (3.35e-1)" "potential prognostic unfavorable (8.77e-4)" "unprognostic (4.66e-1)" "unprognostic (1.14e-1)" "unprognostic (2.68e-1)" "unprognostic (3.13e-1)" TIMM9 TIM9A ENSG00000100575 "Translocase of inner mitochondrial membrane 9" Q9Y5J7 14 58408495-58427531 "Essential proteins, Predicted intracellular proteins" "Protein transport, Translocation, Transport" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" HPA002932 Approved Supported Mitochondria NA NA 19000 "Cluster 24: Non-specific - Transcription" "Cluster 24: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 15: Non-specific - Protein processing" 9 Mitochondria "HPA002932: " "unprognostic (2.15e-2)" "unprognostic (1.08e-1)" "unprognostic (4.90e-2)" "unprognostic (1.12e-1)" "unprognostic (5.56e-2)" "unprognostic (1.37e-1)" "unprognostic (2.74e-1)" "unprognostic (1.14e-2)" "potential prognostic unfavorable (5.83e-4)" "unprognostic (2.21e-3)" "potential prognostic favorable (2.38e-5)" "unprognostic (3.74e-3)" "unprognostic (5.28e-2)" "potential prognostic unfavorable (8.35e-6)" "unprognostic (1.89e-3)" "potential prognostic unfavorable (7.29e-5)" "unprognostic (2.39e-2)" "unprognostic (1.19e-2)" "unprognostic (6.66e-3)" "unprognostic (1.95e-1)" "unprognostic (4.27e-2)" "unprognostic (1.25e-2)" "unprognostic (1.28e-2)" "unprognostic (1.21e-3)" "unprognostic (1.25e-1)" "unprognostic (2.62e-3)" "unprognostic (1.10e-2)" "unprognostic (2.29e-3)" "unprognostic (2.98e-1)" "unprognostic (2.92e-2)" "unprognostic (4.85e-2)" TIMMDC1 "C3orf1, FLJ22597" ENSG00000113845 "Translocase of inner mitochondrial membrane domain containing 1" Q9NPL8 3 119498547-119525090 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Chaperone "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 218.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053214, HPA055846" Uncertain Enhanced Nucleoplasm,Mitochondria NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 27: Non-specific - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 111 Mitochondria Nucleoplasm "HPA053214: , HPA055846: " "unprognostic (4.45e-1)" "unprognostic (1.64e-2)" "unprognostic (5.56e-2)" "unprognostic (2.74e-2)" "unprognostic (2.54e-1)" "unprognostic (2.27e-1)" "unprognostic (3.67e-1)" "unprognostic (8.11e-2)" "unprognostic (1.56e-2)" "unprognostic (1.25e-2)" "unprognostic (4.35e-2)" "unprognostic (1.68e-1)" "potential prognostic unfavorable (2.96e-6)" "unprognostic (1.14e-3)" "unprognostic (8.43e-2)" "unprognostic (4.66e-2)" "unprognostic (4.06e-3)" "unprognostic (2.71e-1)" "unprognostic (8.11e-2)" "unprognostic (1.48e-2)" "unprognostic (3.15e-2)" "unprognostic (7.44e-3)" "unprognostic (3.48e-1)" "unprognostic (7.41e-2)" "unprognostic (3.78e-2)" "unprognostic (1.81e-2)" "unprognostic (3.34e-2)" "unprognostic (1.72e-1)" "unprognostic (1.58e-1)" "unprognostic (1.89e-1)" TIMP1 "CLGI, EPO, TIMP" ENSG00000102265 "TIMP metallopeptidase inhibitor 1" P01033 X 47582408-47586789 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor, Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 2942.8" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 4736.3;Endometrial secretory cells: 1734.3;Fibroblasts: 2389.5;Hepatic stellate cells: 3233.9;Leydig cells: 1234.6;Mesothelial cells: 2073.5;monocytes: 1947.4;Ovarian stromal cells: 1253.0;Peritubular myoid cells: 1506.2;Platelets: 3245.3" "Cell type enhanced" "Detected in many" "fibroblast: 110.8;pericyte: 150.2;vascular associated smooth muscle cell: 88.0" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "thalamus: 427.6" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Liver - Vascular endothelial cells, Stomach - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB022360, HPA053417, CAB080273" Approved Approved "Golgi apparatus,Vesicles" "Secreted to blood" "Growth factor" NA NA 127000000 110000000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 12: Non-specific - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 20 "Golgi apparatus, Vesicles" "CAB022360: , CAB080273: , HPA053417: " "unprognostic (8.81e-3)" "unprognostic (6.05e-3)" "unprognostic (3.70e-2)" "unprognostic (2.37e-2)" "unprognostic (2.22e-3)" "unprognostic (1.26e-1)" "unprognostic (7.17e-3)" "potential prognostic unfavorable (1.27e-5)" "unprognostic (2.09e-3)" "unprognostic (5.13e-2)" "potential prognostic unfavorable (1.14e-8)" "unprognostic (3.30e-3)" "unprognostic (6.55e-3)" "unprognostic (4.16e-2)" "unprognostic (2.85e-2)" "unprognostic (1.73e-3)" "potential prognostic unfavorable (3.10e-4)" "unprognostic (1.58e-2)" "unprognostic (6.77e-3)" "unprognostic (4.09e-2)" "unprognostic (4.87e-2)" "unprognostic (1.59e-1)" "unprognostic (8.34e-2)" "unprognostic (1.72e-1)" "unprognostic (4.42e-3)" "unprognostic (8.47e-3)" "unprognostic (5.54e-2)" "unprognostic (3.08e-2)" "unprognostic (1.14e-1)" "unprognostic (3.22e-2)" "unprognostic (2.60e-1)" TIMP2 CSC-21K ENSG00000035862 "TIMP metallopeptidase inhibitor 2" P16035 17 78852977-78925387 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 500.1;Hofbauer cells: 429.2;Late spermatids: 684.1;Leydig cells: 387.1;Melanocytes: 403.7;Neutrophils: 739.4;Peritubular myoid cells: 828.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 13.9" "Group enriched" "Detected in many" 4 "granulocytes: 13.9;monocytes: 5.1" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Fibroblasts, Breast - Fibroblasts, Colon - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblasts_1, Pituitary gland - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblasts_2, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010203 Approved "Secreted to extracellular matrix" "Enzyme inhibitor" NA NA 72000000 "Cluster 7: Non-specific - Innate immune response" "Cluster 75: Ovary - Mixed function" "Cluster 27: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 20 "CAB010203: " "unprognostic (6.86e-2)" "unprognostic (2.99e-1)" "unprognostic (2.35e-1)" "unprognostic (7.61e-3)" "unprognostic (4.59e-2)" "unprognostic (2.87e-2)" "unprognostic (1.15e-1)" "unprognostic (7.24e-2)" "unprognostic (1.56e-1)" "unprognostic (2.73e-2)" "unprognostic (1.77e-3)" "unprognostic (4.95e-2)" "unprognostic (1.24e-1)" "unprognostic (4.36e-1)" "unprognostic (1.39e-1)" "unprognostic (1.42e-3)" "unprognostic (1.13e-2)" "unprognostic (1.76e-2)" "unprognostic (3.70e-1)" "unprognostic (1.10e-2)" "unprognostic (5.52e-3)" "unprognostic (7.86e-2)" "unprognostic (3.29e-1)" "unprognostic (1.90e-1)" "unprognostic (8.68e-2)" "unprognostic (4.52e-3)" "unprognostic (4.37e-1)" "potential prognostic unfavorable (2.51e-4)" "unprognostic (4.39e-2)" "unprognostic (4.82e-1)" "unprognostic (2.20e-3)" TIMP3 SFD ENSG00000100234 "TIMP metallopeptidase inhibitor 3" P35625 22 32801705-32863041 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Sensory transduction, Vision" "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 2805.9;Decidual stromal cells: 4574.6;Fibroblasts: 1968.9;Leydig cells: 1627.5;Lymphatic endothelial cells: 1941.7;Migrating cytotrophoblasts: 1643.2;Pericytes: 2450.6;Peritubular myoid cells: 2271.6;Pituicytes/FSCs: 2468.7;Retinal pigment epithelial cells: 5848.8;Vascular endothelial cells: 1686.7" "Group enriched" "Detected in all" 4 "astrocyte: 413.9;choroid plexus epithelial cell: 324.5;endothelial cell: 773.2;fibroblast: 1119.7;pericyte: 612.5;vascular associated smooth muscle cell: 1297.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 604.6" "Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068391 Approved "Golgi apparatus,Vesicles" "Secreted to extracellular matrix" "Enzyme inhibitor" NA NA 450000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 110: Mural cells - ECM organization" 20 Vesicles "Golgi apparatus" "HPA068391: " "unprognostic (1.79e-2)" "unprognostic (9.16e-2)" "unprognostic (2.73e-1)" "unprognostic (9.63e-2)" "unprognostic (2.45e-2)" "unprognostic (4.58e-2)" "unprognostic (5.85e-2)" "unprognostic (4.81e-2)" "unprognostic (3.06e-3)" "unprognostic (1.35e-1)" "validated prognostic favorable (1.59e-11)" "validated prognostic favorable (4.75e-5)" "unprognostic (6.17e-2)" "unprognostic (6.91e-3)" "unprognostic (1.68e-2)" "unprognostic (9.56e-2)" "unprognostic (3.17e-2)" "unprognostic (3.64e-3)" "unprognostic (1.96e-1)" "validated prognostic unfavorable (4.50e-5)" "validated prognostic unfavorable (5.12e-8)" "unprognostic (3.78e-2)" "unprognostic (3.92e-1)" "unprognostic (2.60e-2)" "unprognostic (3.51e-1)" "unprognostic (4.22e-3)" "unprognostic (1.15e-1)" "unprognostic (3.57e-3)" "unprognostic (9.62e-2)" "unprognostic (1.79e-2)" "unprognostic (1.31e-1)" TIMP4 ENSG00000157150 "TIMP metallopeptidase inhibitor 4" Q99727 3 12153068-12158912 "Plasma proteins, Predicted secreted proteins" "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 229.4;breast: 171.9" "Cell type enhanced" "Detected in many" "Adipocytes: 20.9;Bergmann glia: 99.6;Breast lactating cells: 101.5;Fibroblasts: 25.8;Hepatic stellate cells: 38.7;Pericytes: 54.1;Schwann cells: 66.8;Vascular endothelial cells: 33.9;Vascular smooth muscle cells: 41.5" "Cell type enriched" "Detected in some" 7 "Bergmann glia: 138.4" "Cancer enriched" "Detected in many" 15 "Glioblastoma Multiforme (TCGA): 152.0" "Region enhanced" "Detected in all" "cerebellum: 102.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Fibroblasts, Breast - Adipocytes (Breast), Pituitary gland - Somatotropes, Spleen - Fibroblasts_2, Thyroid gland - Thyroid glandular cells" "Region enhanced" "Detected in all" "cerebellum: 106.1" "Region enriched" "Detected in all" 9 "cerebellum: 63.5" "Secreted to extracellular matrix" "Enzyme inhibitor" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 35: Non-specific - DNA binding" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 110: Mural cells - ECM organization" 2 "unprognostic (2.61e-1)" "unprognostic (1.13e-1)" "potential prognostic favorable (4.66e-4)" "unprognostic (5.49e-2)" "unprognostic (6.31e-2)" "unprognostic (1.85e-2)" "unprognostic (2.34e-1)" "potential prognostic favorable (9.44e-8)" "unprognostic (1.99e-3)" "unprognostic (5.39e-2)" "unprognostic (2.00e-2)" "unprognostic (1.81e-1)" "unprognostic (1.90e-3)" "unprognostic (8.78e-3)" "unprognostic (2.90e-1)" "unprognostic (2.23e-2)" "unprognostic (3.14e-1)" "unprognostic (8.38e-2)" "unprognostic (1.50e-1)" "unprognostic (2.68e-1)" "unprognostic (8.52e-2)" "unprognostic (5.49e-3)" "potential prognostic unfavorable (3.12e-4)" TINAG ENSG00000137251 "Tubulointerstitial nephritis antigen" Q9UJW2 6 54307859-54390142 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "kidney: 102.8" "Group enriched" "Detected in some" 5 "Colonocytes: 119.0;Enterocytes: 207.3;Proximal tubule cells: 472.7" "Cell type enriched" "Detected in some" 10 "lower rhombic lip: 79.3" "Group enriched" "Detected in many" 5 "Kidney Renal Clear Cell Carcinoma (TCGA): 29.3;Kidney Renal Papillary Cell Carcinoma (TCGA): 36.6" "Region enhanced" "Detected in some" "pons: 4.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney cancer: 12.4" "Colon - Colon enterocytes, Kidney - Proximal tubular cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA035427, HPA073753" Approved "Secreted to extracellular matrix" "Cell adhesion" NA NA 31000 "Cluster 72: Kidney - Transmembrane transport" "Cluster 49: Hindbrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 88: Proximal tubular cells - Transmembrane transport" "HPA035427: , HPA073753: " "unprognostic (3.44e-3)" "unprognostic (1.03e-1)" "unprognostic (3.74e-2)" "validated prognostic favorable (3.44e-7)" "validated prognostic favorable (9.39e-5)" "unprognostic (2.45e-2)" "potential prognostic unfavorable (1.88e-5)" "unprognostic (6.91e-2)" "unprognostic (2.20e-2)" "unprognostic (1.53e-2)" "unprognostic (3.99e-1)" "unprognostic (2.32e-2)" "unprognostic (9.31e-2)" "unprognostic (7.51e-2)" TINAGL1 "ARG1, LCN7, LIECG3, P3ECSL, TINAGRP" ENSG00000142910 "Tubulointerstitial nephritis antigen like 1" Q9GZM7 1 31576485-31587686 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 305.7" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 1416.5;Migrating cytotrophoblasts: 1096.0;Syncytiotrophoblasts: 2158.0" "Group enriched" "Detected in some" 25 "endothelial cell: 72.0;pericyte: 174.1;vascular associated smooth muscle cell: 248.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.0" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 328.7" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Liver - Vascular endothelial cells, Lung - Smooth muscle cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048695 Approved "Secreted to extracellular matrix" "No annotated function" NA NA 180000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 11 "HPA048695: " "unprognostic (3.08e-2)" "unprognostic (3.33e-1)" "unprognostic (3.05e-1)" "unprognostic (5.29e-3)" "potential prognostic favorable (9.19e-4)" "potential prognostic unfavorable (3.97e-4)" "unprognostic (1.68e-1)" "unprognostic (1.15e-1)" "potential prognostic unfavorable (5.08e-4)" "unprognostic (8.01e-2)" "validated prognostic favorable (9.33e-6)" "validated prognostic favorable (7.51e-4)" "potential prognostic favorable (2.29e-5)" "unprognostic (4.40e-3)" "unprognostic (2.72e-1)" "unprognostic (1.12e-1)" "unprognostic (3.43e-2)" "potential prognostic unfavorable (6.72e-4)" "unprognostic (2.41e-3)" "unprognostic (1.13e-1)" "unprognostic (1.61e-2)" "unprognostic (7.11e-3)" "unprognostic (2.20e-1)" "unprognostic (1.44e-1)" "unprognostic (6.32e-2)" "unprognostic (4.30e-2)" "unprognostic (3.31e-2)" "unprognostic (3.70e-2)" "unprognostic (1.11e-1)" "unprognostic (5.52e-3)" "unprognostic (1.42e-1)" TINCR "FLJ90734, LINC00036, NCRNA00036, onco-lncRNA-16, PLAC2" ENSG00000223573 "TINCR ubiquitin domain containing" A0A2R8Y7D0 19 5558167-5578349 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 37.8;skin 1: 134.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 82.1;Cytotrophoblasts: 173.9;Esophageal apical cells: 360.9;Esophageal basal cells: 99.8;Esophageal suprabasal cells: 93.7;Extravillous trophoblasts: 389.1;Migrating cytotrophoblasts: 225.8;Ocular epithelial cells: 87.7;Suprabasal keratinocytes: 120.6;Syncytiotrophoblasts: 698.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.1" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "breast cancer: 26.0;cervical cancer: 23.2" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Lung - Alveolar cells type 1, Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Prostate glandular cells, Skin - Keratinocyte (other), Testis - Spermatogonia" "Low region specificity" "Detected in all" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 37: Skin - Keratinization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." 1 "unprognostic (2.95e-3)" "unprognostic (7.95e-3)" "unprognostic (6.10e-2)" "unprognostic (1.72e-1)" "unprognostic (1.20e-1)" "unprognostic (1.35e-1)" "unprognostic (2.14e-3)" "unprognostic (3.33e-3)" "unprognostic (1.61e-2)" "potential prognostic unfavorable (2.63e-5)" "unprognostic (1.38e-1)" "unprognostic (2.72e-1)" "unprognostic (2.06e-1)" "unprognostic (9.39e-2)" "unprognostic (1.73e-2)" "unprognostic (5.65e-2)" "unprognostic (8.69e-3)" "unprognostic (2.56e-1)" "unprognostic (3.18e-3)" "unprognostic (8.36e-2)" "unprognostic (3.02e-1)" "unprognostic (1.08e-1)" "unprognostic (1.47e-1)" "unprognostic (9.52e-2)" "unprognostic (1.82e-1)" TINF2 TIN2 ENSG00000092330 "TERF1 interacting nuclear factor 2" Q9BSI4 14 24238286-24242663 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Disease variant, Dyskeratosis congenita" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "parathyroid gland: 219.4" "Cell type enhanced" "Detected in many" "Bergmann glia: 8.7;Differentiating spermatogonia: 13.9;Early primary spermatocytes: 14.5;Late spermatids: 8.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059061, HPA069807" Enhanced "Nuclear bodies" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 27: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 98: Neurons - Neurotransmission & signaling" 64 "Nuclear bodies" "HPA059061: , HPA069807: " "unprognostic (1.14e-1)" "unprognostic (1.51e-2)" "unprognostic (3.59e-2)" "unprognostic (1.39e-1)" "unprognostic (2.20e-1)" "unprognostic (5.14e-2)" "unprognostic (3.10e-2)" "unprognostic (3.95e-1)" "unprognostic (1.11e-1)" "unprognostic (1.06e-2)" "potential prognostic favorable (9.27e-4)" "unprognostic (2.21e-2)" "unprognostic (1.07e-1)" "unprognostic (4.54e-2)" "unprognostic (3.16e-1)" "unprognostic (1.66e-1)" "unprognostic (5.34e-2)" "unprognostic (2.43e-1)" "unprognostic (2.96e-1)" "unprognostic (3.75e-1)" "unprognostic (2.65e-1)" "unprognostic (1.61e-1)" "unprognostic (4.67e-1)" "unprognostic (1.50e-2)" "unprognostic (8.08e-2)" "unprognostic (1.32e-1)" "unprognostic (1.33e-1)" "unprognostic (2.83e-2)" "unprognostic (1.41e-1)" "unprognostic (1.75e-1)" "unprognostic (6.37e-2)" TIPARP "ARTD14, DDF1, DKFZP434J214, DKFZp686N0351, PARP-1, PARP-7, PARP7, pART14, RM1" ENSG00000163659 "TCDD inducible poly(ADP-ribose) polymerase" Q7Z3E1 3 156673235-156706770 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial secretory cells: 424.9;Urothelial cells: 532.1" "Cell type enhanced" "Detected in all" "endothelial cell: 101.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 53.6" "Lineage enriched" "Detected in all" 5 "granulocytes: 53.6" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary gland basal cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036796 Approved Microtubules NA NA "Cluster 41: Basophils - Unknown function" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 103: Non-specific - Basic cellular processes" 3 Microtubules "HPA036796: " "unprognostic (8.87e-2)" "potential prognostic favorable (3.63e-4)" "unprognostic (1.99e-1)" "unprognostic (2.12e-1)" "unprognostic (3.82e-2)" "unprognostic (1.64e-2)" "unprognostic (2.67e-1)" "unprognostic (2.18e-2)" "unprognostic (6.67e-2)" "unprognostic (1.60e-2)" "potential prognostic favorable (8.84e-5)" "unprognostic (2.58e-2)" "unprognostic (1.16e-1)" "unprognostic (4.31e-2)" "unprognostic (2.27e-1)" "unprognostic (2.97e-1)" "unprognostic (3.49e-3)" "unprognostic (5.39e-3)" "unprognostic (8.26e-2)" "unprognostic (9.02e-2)" "unprognostic (2.48e-1)" "unprognostic (9.05e-3)" "unprognostic (1.58e-2)" "unprognostic (2.16e-1)" "unprognostic (1.24e-1)" "unprognostic (6.34e-2)" "unprognostic (7.28e-2)" "unprognostic (7.27e-2)" "unprognostic (1.74e-1)" "unprognostic (2.88e-2)" "unprognostic (1.81e-2)" TIPIN FLJ20516 ENSG00000075131 "TIMELESS interacting protein" Q9BVW5 15 66336191-66386746 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 78.0;Early primary spermatocytes: 153.9;Late primary spermatocytes: 96.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039704, HPA058799" Enhanced NA Yes "Cluster 33: Non-specific - ATP binding" "Cluster 39: Testis - Nuclear processes" "Cluster 2: Neurons - Nucleosome" "Cluster 58: Non-specific - Nuclear processes" "Cluster 3: Early primary spermatocytes - Early meiosis" 14 "HPA039704: , HPA058799: " "unprognostic (3.43e-3)" "unprognostic (2.70e-1)" "unprognostic (2.56e-1)" "unprognostic (2.70e-2)" "unprognostic (5.25e-1)" "unprognostic (5.12e-2)" "unprognostic (9.16e-2)" "unprognostic (3.67e-1)" "unprognostic (6.13e-2)" "unprognostic (1.62e-3)" "unprognostic (2.64e-3)" "unprognostic (5.91e-2)" "unprognostic (1.07e-2)" "validated prognostic unfavorable (3.76e-4)" "validated prognostic unfavorable (1.58e-7)" "unprognostic (1.33e-3)" "unprognostic (3.06e-2)" "unprognostic (1.28e-3)" "unprognostic (3.27e-1)" "unprognostic (2.63e-2)" "unprognostic (1.09e-2)" "unprognostic (3.89e-1)" "unprognostic (2.12e-2)" "unprognostic (7.87e-3)" "unprognostic (2.44e-2)" "unprognostic (1.17e-1)" "unprognostic (1.78e-2)" "unprognostic (9.08e-2)" "unprognostic (2.90e-1)" "unprognostic (8.61e-2)" "unprognostic (2.16e-1)" TIPRL "dJ69E11.3, MGC3794, TIP41, TIPRL1" ENSG00000143155 "TOR signaling pathway regulator" O75663 1 168178962-168202109 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027995, HPA054282" Approved Approved Vesicles NA NA 13000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 97: Non-specific - Cellular respiration" 23 Vesicles "HPA027995: , HPA054282: " "unprognostic (1.68e-1)" "unprognostic (9.65e-3)" "unprognostic (3.05e-1)" "unprognostic (1.41e-2)" "unprognostic (1.95e-1)" "unprognostic (1.38e-1)" "unprognostic (4.00e-2)" "unprognostic (5.45e-2)" "unprognostic (1.32e-1)" "unprognostic (2.24e-3)" "unprognostic (6.68e-3)" "unprognostic (2.82e-1)" "unprognostic (1.06e-3)" "potential prognostic unfavorable (7.60e-4)" "unprognostic (2.59e-2)" "unprognostic (1.37e-2)" "unprognostic (6.40e-2)" "unprognostic (4.99e-2)" "unprognostic (2.33e-1)" "unprognostic (1.18e-1)" "potential prognostic unfavorable (2.32e-4)" "unprognostic (2.33e-3)" "unprognostic (1.18e-2)" "unprognostic (1.89e-1)" "unprognostic (2.67e-1)" "unprognostic (1.09e-2)" "unprognostic (4.79e-3)" "unprognostic (3.25e-1)" "unprognostic (1.16e-1)" "unprognostic (1.42e-2)" "unprognostic (1.65e-1)" TIRAP "Mal, wyatt" ENSG00000150455 "TIR domain containing adaptor protein" P58753 11 126282497-126298845 "Predicted intracellular proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054431 Uncertain Approved "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes NA "Cluster 7: Non-specific - Innate immune response" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 2: Neurons - Nucleosome" "Cluster 24: Non-specific - Unknown function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 32 "Nucleoplasm, Cytokinetic bridge, Cytosol" "HPA054431: " "unprognostic (2.20e-1)" "unprognostic (3.40e-3)" "unprognostic (2.06e-1)" "unprognostic (7.53e-2)" "unprognostic (1.96e-1)" "unprognostic (8.47e-3)" "unprognostic (1.51e-1)" "unprognostic (3.09e-1)" "unprognostic (4.90e-2)" "unprognostic (8.13e-2)" "validated prognostic favorable (4.15e-8)" "validated prognostic favorable (4.01e-4)" "unprognostic (3.36e-2)" "unprognostic (5.08e-2)" "unprognostic (1.08e-1)" "unprognostic (1.03e-3)" "unprognostic (2.14e-1)" "unprognostic (1.86e-1)" "unprognostic (1.58e-2)" "unprognostic (2.46e-1)" "unprognostic (3.65e-2)" "unprognostic (7.45e-2)" "unprognostic (3.64e-1)" "unprognostic (1.98e-1)" "unprognostic (4.59e-2)" "unprognostic (1.65e-1)" "unprognostic (6.81e-2)" "unprognostic (1.57e-2)" "unprognostic (3.16e-1)" "unprognostic (5.84e-2)" "unprognostic (1.28e-1)" TJAP1 "PILT, TJP4" ENSG00000137221 "Tight junction associated protein 1" Q5JTD0 6 43477523-43506556 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 121.0" "Cell type enhanced" "Detected in all" "oligodendrocyte: 140.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030164, HPA030165, HPA030166" Supported Enhanced "Golgi apparatus" NA NA "Cluster 32: Basophils - Transcription" "Cluster 24: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 11: Neuronal - Sensory perception" "Cluster 80: Oligodendrocytes - Myelination" 5 "Golgi apparatus" "HPA030164: , HPA030165: , HPA030166: " "unprognostic (5.19e-2)" "unprognostic (2.77e-2)" "unprognostic (1.99e-1)" "unprognostic (2.85e-1)" "unprognostic (2.74e-2)" "unprognostic (8.16e-2)" "unprognostic (1.67e-1)" "unprognostic (6.33e-2)" "unprognostic (3.09e-3)" "potential prognostic unfavorable (7.91e-4)" "unprognostic (2.32e-2)" "unprognostic (2.25e-2)" "unprognostic (2.61e-1)" "potential prognostic unfavorable (6.45e-7)" "unprognostic (2.32e-2)" "unprognostic (2.47e-1)" "unprognostic (1.59e-2)" "unprognostic (1.24e-1)" "unprognostic (2.10e-3)" "unprognostic (1.55e-1)" "unprognostic (4.06e-2)" "unprognostic (4.03e-2)" "unprognostic (5.71e-3)" "potential prognostic unfavorable (5.72e-4)" "unprognostic (2.09e-2)" "unprognostic (8.51e-3)" "unprognostic (1.43e-2)" "unprognostic (3.41e-1)" "unprognostic (5.03e-2)" "unprognostic (1.05e-2)" "unprognostic (6.19e-2)" TJP1 "DKFZp686M05161, MGC133289, ZO-1" ENSG00000104067 "Tight junction protein 1" Q07157 15 29699367-29968915 "Predicted intracellular proteins, Transporters" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 502.5;Brain inhibitory neurons: 339.1;Oligodendrocyte progenitor cells: 519.1;Oligodendrocytes: 1082.2;Podocytes: 1678.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Breast - Endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001636, HPA001637, CAB010822" Enhanced Enhanced "Cell Junctions" NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 104: Brain endothelial cells - Blood brain barrier" 44 "Cell Junctions" "CAB010822: , HPA001636: , HPA001637: " "unprognostic (1.59e-1)" "unprognostic (2.89e-2)" "unprognostic (2.99e-1)" "unprognostic (2.80e-2)" "unprognostic (2.84e-1)" "unprognostic (2.68e-2)" "unprognostic (5.18e-2)" "unprognostic (1.30e-1)" "unprognostic (2.82e-1)" "unprognostic (5.04e-2)" "validated prognostic favorable (5.38e-5)" "validated prognostic favorable (3.00e-4)" "unprognostic (8.66e-2)" "unprognostic (1.53e-1)" "unprognostic (3.60e-3)" "unprognostic (6.42e-3)" "unprognostic (2.90e-3)" "unprognostic (6.07e-2)" "unprognostic (2.17e-1)" "unprognostic (1.09e-1)" "unprognostic (9.01e-2)" "unprognostic (2.38e-3)" "unprognostic (1.95e-2)" "unprognostic (2.95e-1)" "unprognostic (3.49e-1)" "unprognostic (2.67e-2)" "unprognostic (3.10e-1)" "unprognostic (1.50e-2)" "unprognostic (1.83e-1)" "unprognostic (9.71e-2)" "unprognostic (5.86e-2)" TJP2 "DFNA51, X104, ZO-2, ZO2" ENSG00000119139 "Tight junction protein 2" Q9UDY2 9 69121264-69274615 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 113.3;Bergmann glia: 343.0;Foveolar cells: 39.9;Oligodendrocytes: 63.4;Tuft cells: 34.6" "Cell type enhanced" "Detected in all" "astrocyte: 211.9;Bergmann glia: 370.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001813, CAB009228, HPA070714" Supported Enhanced "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA 1100000 "Cluster 40: Monocytes - Innate immune response" "Cluster 42: Retina - Visual perception" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 28: Astrocytes - Homeostasis & neuron support" 53 "Plasma membrane, Cell Junctions" Nucleoplasm "CAB009228: , HPA001813: , HPA070714: " "unprognostic (1.11e-1)" "unprognostic (1.16e-1)" "unprognostic (2.27e-1)" "unprognostic (1.54e-1)" "unprognostic (1.17e-1)" "unprognostic (1.03e-1)" "unprognostic (2.31e-1)" "unprognostic (2.32e-2)" "unprognostic (9.98e-2)" "unprognostic (9.50e-2)" "validated prognostic favorable (1.97e-12)" "validated prognostic favorable (1.52e-5)" "unprognostic (1.45e-2)" "unprognostic (7.33e-3)" "unprognostic (5.82e-2)" "unprognostic (5.35e-2)" "unprognostic (1.07e-1)" "unprognostic (4.13e-2)" "unprognostic (2.79e-2)" "unprognostic (3.52e-2)" "unprognostic (3.41e-1)" "unprognostic (1.51e-3)" "unprognostic (4.05e-1)" "unprognostic (1.46e-1)" "unprognostic (1.48e-2)" "unprognostic (4.44e-2)" "unprognostic (7.58e-3)" "unprognostic (1.89e-2)" "unprognostic (1.70e-1)" "unprognostic (2.07e-2)" "unprognostic (1.60e-1)" TJP3 ZO-3 ENSG00000105289 "Tight junction protein 3" O95049 19 3708362-3750813 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 24.6;intestine: 40.5;stomach 1: 25.5" "Cell type enhanced" "Detected in many" "Breast lactating cells: 146.5;Colonocytes: 257.4;Early spermatids: 404.4;Enterocytes: 197.9;Esophageal apical cells: 313.3;Foveolar cells: 173.4;Late primary spermatocytes: 321.5;Respiratory ciliated cells: 190.9" "Cell type enriched" "Detected in many" 4 "choroid plexus epithelial cell: 24.5" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 9 "choroid plexus: 16.2" "Group enriched" "Detected in many" 5 "gdT-cell: 1.2;MAIT T-cell: 3.9;memory CD4 T-cell: 3.1;memory CD8 T-cell: 2.4;naive CD4 T-cell: 3.3;naive CD8 T-cell: 1.2;T-reg: 3.8" "Lineage enriched" "Detected in single" 7 "T-cells: 3.9" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Prostate - Urothelial cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" "CAB013244, HPA046863, HPA053337" Enhanced Enhanced "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 17: Intestine - Digestion" "Cluster 36: Choroid plexus - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 1 "Nucleoplasm, Cell Junctions" "Plasma membrane" "CAB013244: , HPA046863: , HPA053337: " "unprognostic (5.50e-3)" "unprognostic (6.04e-2)" "unprognostic (6.58e-2)" "unprognostic (8.16e-2)" "unprognostic (1.14e-1)" "unprognostic (3.67e-2)" "unprognostic (1.18e-2)" "unprognostic (7.44e-2)" "unprognostic (3.44e-2)" "unprognostic (6.07e-2)" "unprognostic (4.91e-2)" "unprognostic (7.44e-2)" "unprognostic (8.16e-2)" "unprognostic (1.47e-3)" "unprognostic (1.51e-1)" "unprognostic (5.09e-2)" "unprognostic (2.99e-1)" "unprognostic (3.43e-3)" "unprognostic (3.02e-2)" "unprognostic (6.66e-2)" "unprognostic (9.41e-2)" "unprognostic (1.21e-1)" "potential prognostic favorable (9.81e-4)" "unprognostic (9.73e-2)" "unprognostic (9.59e-2)" "unprognostic (9.70e-2)" TK1 ENSG00000167900 "Thymidine kinase 1" P04183 17 78174091-78187233 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA synthesis" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 73.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 100.0;Enteric stem cells: 69.4;Enteric transient amplifying cells: 143.9;Erythrocyte progenitors: 109.9;Esophageal basal cells: 187.9;Extravillous trophoblasts: 248.6;Gastric progenitor cells: 101.3;Hofbauer cells: 86.0;Megakaryocyte progenitors: 80.5;Megakaryocytes: 61.8;Migrating cytotrophoblasts: 185.6;Monocyte progenitors: 90.3;Paneth cells: 81.2" "Cell type enhanced" "Detected in some" "endothelial cell: 2.4;medium spiny neuron: 2.3;oligodendrocyte: 2.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 34.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach)" "Region enhanced" "Detected in some" "white matter: 3.6" "Low region specificity" "Detected in many" CAB004683 Enhanced NA Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 27: Breast cancer - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 56 "CAB004683: " "unprognostic (2.87e-2)" "unprognostic (2.32e-2)" "unprognostic (2.91e-1)" "unprognostic (1.66e-2)" "unprognostic (7.83e-2)" "unprognostic (1.11e-1)" "unprognostic (6.40e-2)" "unprognostic (1.34e-1)" "unprognostic (1.88e-1)" "potential prognostic unfavorable (1.83e-4)" "validated prognostic unfavorable (4.76e-9)" "validated prognostic unfavorable (5.34e-4)" "potential prognostic unfavorable (1.00e-7)" "validated prognostic unfavorable (4.44e-4)" "validated prognostic unfavorable (1.56e-5)" "validated prognostic unfavorable (3.78e-6)" "validated prognostic unfavorable (8.73e-4)" "unprognostic (1.07e-1)" "unprognostic (5.34e-2)" "unprognostic (1.75e-1)" "unprognostic (4.69e-3)" "unprognostic (2.57e-3)" "unprognostic (7.19e-2)" "unprognostic (3.56e-2)" "unprognostic (1.91e-1)" "unprognostic (1.04e-1)" "unprognostic (2.52e-2)" "unprognostic (6.95e-3)" "unprognostic (2.28e-1)" "unprognostic (1.04e-1)" "unprognostic (6.80e-2)" TK2 SCA31 ENSG00000166548 "Thymidine kinase 2" O00142 16 66508003-66552544 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "DNA synthesis" "Kinase, Transferase" "Disease variant, FDA approved drug targets, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 61.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041162 Uncertain NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 67: Testis - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 1 "HPA041162: " "unprognostic (9.94e-3)" "unprognostic (4.23e-2)" "unprognostic (4.34e-2)" "unprognostic (2.61e-1)" "unprognostic (1.33e-1)" "unprognostic (2.28e-1)" "unprognostic (3.29e-1)" "unprognostic (1.66e-2)" "unprognostic (3.17e-1)" "unprognostic (4.17e-2)" "potential prognostic favorable (4.03e-4)" "unprognostic (1.21e-1)" "potential prognostic favorable (3.64e-7)" "unprognostic (2.82e-1)" "unprognostic (1.16e-2)" "unprognostic (1.10e-1)" "unprognostic (1.69e-2)" "unprognostic (3.82e-2)" "unprognostic (6.92e-2)" "unprognostic (1.18e-1)" "unprognostic (1.06e-2)" "unprognostic (2.87e-2)" "unprognostic (1.02e-1)" "unprognostic (2.40e-1)" "unprognostic (6.32e-2)" "unprognostic (1.52e-1)" "unprognostic (4.71e-1)" "unprognostic (9.71e-2)" "unprognostic (6.12e-2)" "unprognostic (7.92e-2)" "unprognostic (1.50e-3)" TKFC "DAK, DKFZP586B1621, NET45" ENSG00000149476 "Triokinase and FMN cyclase" Q3LXA3 11 61333220-61353295 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Lyase, Multifunctional enzyme, Transferase" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 181.3;liver: 108.3" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 64.8;Enteric transient amplifying cells: 71.9;Enterocytes: 374.6;Hepatocytes: 154.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells, Liver - Hepatocytes, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039486, HPA048186" Enhanced Approved Nucleoplasm,Cytosol NA NA 7600000 "Cluster 13: Non-specific - Mitochondria" "Cluster 77: Intestine - Digestion" "Cluster 27: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 1: Enterocytes - Absorption and Digestion" 22 Nucleoplasm Cytosol "HPA039486: , HPA048186: " "unprognostic (8.96e-2)" "unprognostic (8.60e-2)" "unprognostic (2.94e-1)" "unprognostic (1.30e-1)" "unprognostic (1.73e-2)" "unprognostic (1.11e-1)" "unprognostic (1.22e-1)" "unprognostic (8.55e-2)" "unprognostic (1.20e-1)" "potential prognostic favorable (2.11e-8)" "unprognostic (4.53e-1)" "unprognostic (1.42e-2)" "unprognostic (1.88e-2)" "potential prognostic unfavorable (2.03e-4)" "unprognostic (1.15e-2)" "unprognostic (9.07e-2)" "unprognostic (2.62e-1)" "unprognostic (1.18e-1)" "unprognostic (4.40e-2)" "unprognostic (4.50e-2)" "unprognostic (6.28e-2)" "unprognostic (1.53e-1)" "unprognostic (5.58e-3)" "unprognostic (2.16e-1)" "unprognostic (1.92e-1)" "unprognostic (6.86e-2)" "unprognostic (2.02e-1)" "unprognostic (4.11e-1)" "unprognostic (1.53e-2)" TKT ENSG00000163931 Transketolase P29401 3 53224712-53256052 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 630.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 934.6;Alveolar cells type 2: 608.2;Esophageal basal cells: 1040.5;Esophageal suprabasal cells: 608.3;Kupffer cells: 614.9;Neutrophil progenitors: 804.2;Neutrophils: 790.7;Ocular epithelial cells: 1019.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "classical monocyte: 447.4;eosinophil: 274.7;intermediate monocyte: 198.7;myeloid DC: 204.0;neutrophil: 376.1;non-classical monocyte: 243.2" "Group enriched" "Detected in all" 9 "dendritic cells: 204.0;granulocytes: 376.1;monocytes: 447.4" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029480, HPA029481" Enhanced Enhanced "Nucleoplasm,Nuclear speckles,Nuclear bodies" NA NA 120000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 15: Bone marrow - Innate immune response" "Cluster 19: Astrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 100: Stratified epithelial cells - Barrier functions" 22 Nucleoplasm "Nuclear speckles, Nuclear bodies" "HPA029480: , HPA029481: " "potential prognostic unfavorable (8.65e-4)" "unprognostic (1.02e-2)" "unprognostic (1.49e-1)" "unprognostic (1.07e-2)" "unprognostic (1.28e-3)" "unprognostic (8.66e-2)" "unprognostic (1.34e-1)" "unprognostic (1.08e-1)" "unprognostic (1.00e-2)" "unprognostic (5.83e-2)" "unprognostic (1.37e-2)" "unprognostic (5.15e-3)" "unprognostic (1.97e-3)" "validated prognostic unfavorable (8.71e-6)" "validated prognostic unfavorable (1.38e-5)" "unprognostic (1.93e-1)" "unprognostic (3.64e-2)" "unprognostic (1.68e-1)" "unprognostic (3.02e-1)" "unprognostic (1.11e-1)" "unprognostic (4.44e-2)" "potential prognostic unfavorable (4.35e-4)" "unprognostic (9.83e-2)" "unprognostic (3.12e-2)" "unprognostic (1.16e-2)" "unprognostic (3.09e-2)" "unprognostic (2.46e-1)" "unprognostic (2.29e-1)" "unprognostic (5.31e-2)" "unprognostic (1.21e-1)" "unprognostic (1.91e-1)" TKTL1 "TKR, TKT2" ENSG00000007350 "Transketolase like 1" P51854 X 154295795-154330350 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Developmental protein, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 33 "testis: 118.9" "Group enriched" "Detected in some" 11 "Differentiating spermatogonia: 678.2;Early primary spermatocytes: 371.4;Oocytes: 437.5;Undifferentiated spermatogonia: 202.8" "Cell type enhanced" "Detected in some" "leukocyte: 5.0" "Cancer enriched" "Detected in many" 6 "Testicular Germ Cell Tumor (TCGA): 93.1" "Group enriched" "Detected in some" 7 "cerebral cortex: 8.7;medulla oblongata: 3.1" "Group enriched" "Detected in many" 5 "eosinophil: 61.0;gdT-cell: 24.5" "Group enriched" "Detected in many" 5 "granulocytes: 61.0;T-cells: 24.5" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 11.4;Myeloma: 6.8" "Heart muscle - Cardiomyocytes, Lung - NK-cells (Lung), Testis - Spermatocytes, Testis - Spermatogonia" "Not detected" "Not detected" "Region enhanced" "Detected in single" "white matter: 1.3" "HPA000505, HPA029155, CAB032191" Enhanced Enhanced Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 57: Testis - Spermatogenesis" "Cluster 12: Non-specific - Vasculature" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 1 Cytosol "CAB032191: , HPA000505: , HPA029155: " "unprognostic (3.41e-2)" "unprognostic (4.47e-1)" "unprognostic (3.05e-3)" "unprognostic (1.22e-2)" "unprognostic (5.93e-2)" "unprognostic (8.64e-2)" "unprognostic (4.75e-3)" "unprognostic (1.68e-1)" "unprognostic (7.44e-2)" "unprognostic (1.57e-1)" "unprognostic (1.91e-1)" "unprognostic (5.42e-2)" "unprognostic (6.76e-2)" "unprognostic (1.42e-2)" "unprognostic (5.64e-2)" "unprognostic (1.21e-2)" TKTL2 "DKFZP434L1717, FLJ32975" ENSG00000151005 "Transketolase like 2" Q9H0I9 4 163471095-163473754 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 372 "testis: 54.0" "Cell type enriched" "Detected in some" 7 "Late primary spermatocytes: 400.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 1 TLCD1 ENSG00000160606 "TLC domain containing 1" Q96CP7 17 28724348-28727935 "Essential proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Colonocytes: 55.3;Endometrial glandular cells: 43.2;Enterocytes: 48.2;Epididymal basal cells: 64.8;Urothelial cells: 76.9" "Group enriched" "Detected in some" 6 "astrocyte: 7.4;Bergmann glia: 14.9;ependymal cell: 6.1;oligodendrocyte precursor cell: 3.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 11 "plasmacytoid DC: 21.9" "Lineage enriched" "Detected in many" 11 "dendritic cells: 21.9" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042366 Enhanced NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 2: Non-specific - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 65: Non-specific - Cell growth & division" 8 "HPA042366: " "unprognostic (1.41e-1)" "unprognostic (1.92e-1)" "unprognostic (5.37e-2)" "unprognostic (6.79e-2)" "unprognostic (5.01e-3)" "unprognostic (8.00e-2)" "unprognostic (2.48e-2)" "unprognostic (1.03e-3)" "unprognostic (4.24e-2)" "unprognostic (1.42e-1)" "potential prognostic unfavorable (1.29e-10)" "unprognostic (2.25e-3)" "unprognostic (2.09e-2)" "validated prognostic unfavorable (4.19e-4)" "validated prognostic unfavorable (3.43e-6)" "unprognostic (2.41e-2)" "unprognostic (4.12e-2)" "unprognostic (2.21e-2)" "unprognostic (1.26e-1)" "unprognostic (1.37e-2)" "unprognostic (1.09e-1)" "unprognostic (8.45e-2)" "unprognostic (3.94e-1)" "unprognostic (2.47e-1)" "unprognostic (2.48e-1)" "unprognostic (4.22e-2)" "unprognostic (4.60e-2)" "unprognostic (3.20e-1)" "unprognostic (1.03e-1)" "unprognostic (9.07e-2)" "unprognostic (1.02e-1)" TLCD2 ENSG00000185561 "TLC domain containing 2" A6NGC4 17 1702816-1710377 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 2.4;Distal convoluted tubule cells: 1.7;Ependymal cells: 1.4;Loop of henle epithelial cells: 3.1;Papillary tip epithelial cells: 10.9;Podocytes: 6.2;Proximal tubule cells: 2.7;Renal collecting duct intercalated cells: 3.6;Renal collecting duct principal cells: 5.2;Renal connecting tubule cells: 3.9" "Cell type enhanced" "Detected in many" "endothelial cell: 6.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 3.3;neutrophil: 1.5" "Lineage enriched" "Detected in single" 8 "granulocytes: 3.3" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast)" "Not detected" "Not detected" "Region enhanced" "Detected in all" "spinal cord: 18.7" HPA046063 Uncertain Approved Vesicles NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 28: Liver & Adrenal gland - Secretion" "Cluster 6: Non-specific - Immune response" "Cluster 72: Neuronal - Signal transduction" "Cluster 105: Non-specific - Mixed function" Vesicles "HPA046063: " "unprognostic (3.12e-3)" "unprognostic (1.35e-1)" "unprognostic (8.72e-3)" "unprognostic (9.01e-2)" "unprognostic (4.01e-1)" "unprognostic (4.60e-3)" "unprognostic (1.03e-1)" "unprognostic (1.34e-1)" "unprognostic (1.14e-2)" "potential prognostic unfavorable (3.94e-4)" "unprognostic (5.57e-2)" "unprognostic (1.16e-1)" "unprognostic (2.92e-1)" "unprognostic (3.80e-2)" "unprognostic (4.04e-2)" "unprognostic (6.20e-2)" "unprognostic (1.31e-1)" "unprognostic (1.21e-2)" "unprognostic (8.34e-2)" "unprognostic (9.58e-3)" "unprognostic (1.47e-1)" "unprognostic (2.67e-1)" "unprognostic (5.95e-2)" "unprognostic (8.99e-3)" "unprognostic (1.37e-2)" "unprognostic (3.18e-2)" "unprognostic (9.81e-2)" "unprognostic (1.70e-1)" "unprognostic (2.38e-1)" TLCD3A "CT120, FAM57A, FLJ22282" ENSG00000167695 "TLC domain containing 3A" Q8TBR7 17 732412-742968 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 70.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 57.0;Early spermatids: 38.3;Esophageal apical cells: 35.8;Esophageal basal cells: 48.3;Esophageal suprabasal cells: 48.4;Ocular epithelial cells: 36.2;Suprabasal keratinocytes: 63.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 1.5" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 27: T-cells - Unknown function" "Cluster 58: Skin - Keratinization" "Cluster 35: Non-specific - DNA binding" "Cluster 42: Non-specific - Unknown function" "Cluster 26: Keratinocytes - Keratinization" 1 "unprognostic (8.21e-2)" "unprognostic (1.88e-2)" "unprognostic (1.28e-1)" "unprognostic (8.61e-2)" "unprognostic (1.90e-1)" "unprognostic (6.52e-2)" "unprognostic (1.62e-1)" "unprognostic (1.24e-1)" "unprognostic (3.89e-3)" "unprognostic (2.12e-3)" "unprognostic (2.77e-3)" "unprognostic (1.29e-2)" "potential prognostic unfavorable (3.51e-4)" "unprognostic (3.10e-2)" "unprognostic (1.75e-2)" "unprognostic (1.67e-1)" "unprognostic (6.78e-2)" "unprognostic (2.77e-2)" "unprognostic (3.26e-1)" "unprognostic (1.60e-1)" "unprognostic (6.97e-2)" "unprognostic (1.44e-2)" "unprognostic (2.66e-2)" "unprognostic (1.18e-1)" "unprognostic (6.50e-3)" "unprognostic (1.35e-1)" "unprognostic (4.05e-1)" "unprognostic (9.26e-2)" "unprognostic (2.39e-3)" TLCD3B "DKFZP434I2117, FAM57B" ENSG00000149926 "TLC domain containing 3B" Q71RH2 16 30024427-30052978 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Transferase "Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 83.9;retina: 63.1;testis: 99.1" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 97.3;Early primary spermatocytes: 37.0;Early spermatids: 123.6;Late primary spermatocytes: 190.6;Late spermatids: 83.7;Retinal bipolar cells: 25.0;Rod photoreceptor cells: 127.4" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in some" 5 "Glioblastoma Multiforme (TCGA): 12.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Neuroblastoma: 47.9" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pituitary gland - Lactotropes, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 1: Neuronal - Visual perception" "Cluster 79: Photoreceptor cells - Phototransduction" "unprognostic (3.09e-2)" "unprognostic (1.48e-1)" "unprognostic (4.63e-2)" "potential prognostic favorable (2.32e-4)" "potential prognostic unfavorable (1.03e-5)" "unprognostic (2.15e-1)" TLCD4 "FLJ31842, TMEM56" ENSG00000152078 "TLC domain containing 4" Q96MV1 1 95117355-95197607 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 121.5" "Cell type enhanced" "Detected in some" "Astrocytes: 70.9;Bergmann glia: 70.0;Brain excitatory neurons: 36.4;Brain inhibitory neurons: 40.1;Choroid plexus epithelial cells: 23.3;Ependymal cells: 20.5;Erythrocyte progenitors: 15.4;Late spermatids: 18.3;Oligodendrocyte progenitor cells: 39.6;Oligodendrocytes: 36.8;Other brain neurons: 19.5;Retinal pigment epithelial cells: 25.6" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 19.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Smooth muscle cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046762 Approved "Nuclear speckles" No No "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 31: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 28: Astrocytes - Homeostasis & neuron support" 63 "Nuclear speckles" "HPA046762: " "unprognostic (7.65e-3)" "unprognostic (4.17e-3)" "unprognostic (8.33e-2)" "unprognostic (2.93e-3)" "unprognostic (1.99e-2)" "unprognostic (3.74e-2)" "unprognostic (2.95e-2)" "potential prognostic unfavorable (3.20e-4)" "unprognostic (3.39e-3)" "unprognostic (1.84e-1)" "unprognostic (1.68e-2)" "unprognostic (1.35e-2)" "unprognostic (3.00e-2)" "unprognostic (7.77e-3)" "unprognostic (1.63e-1)" "unprognostic (7.80e-3)" "unprognostic (3.01e-2)" "unprognostic (6.70e-2)" "unprognostic (1.39e-1)" "unprognostic (3.23e-1)" "unprognostic (1.15e-1)" "unprognostic (6.15e-2)" "unprognostic (4.25e-2)" "unprognostic (3.71e-3)" "unprognostic (1.16e-1)" "unprognostic (3.68e-2)" "unprognostic (2.55e-1)" "unprognostic (1.87e-1)" TLCD4-RWDD3 TMEM56-RWDD3 ENSG00000271092 "TLCD4-RWDD3 readthrough" 1 95117923-95247225 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Cardiomyocytes: 150.6;Retinal pigment epithelial cells: 85.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 55: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" "unprognostic (3.47e-1)" "unprognostic (2.56e-1)" "unprognostic (2.63e-2)" "unprognostic (5.75e-2)" "unprognostic (2.90e-2)" "unprognostic (1.70e-2)" "unprognostic (3.74e-1)" "unprognostic (5.26e-2)" "unprognostic (2.04e-2)" "unprognostic (2.10e-1)" "unprognostic (1.95e-2)" "unprognostic (4.98e-3)" "unprognostic (7.84e-2)" "unprognostic (3.90e-1)" "unprognostic (4.95e-3)" "unprognostic (2.38e-2)" "unprognostic (1.08e-1)" "unprognostic (1.13e-1)" TLCD5 "MGC17839, TMEM136" ENSG00000181264 "TLC domain containing 5" Q6ZRR5 11 120325296-120333686 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "retina: 48.1" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 45.1;Cone photoreceptor cells: 53.8;Epididymal principal cells: 43.8;Rod photoreceptor cells: 88.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "plasmacytoid DC: 2.2" "Lineage enriched" "Detected in single" 5 "dendritic cells: 2.2" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Spleen - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074432 Approved Vesicles,Cytosol NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 79: Photoreceptor cells - Phototransduction" Vesicles Cytosol "HPA074432: " "unprognostic (7.57e-3)" "unprognostic (1.15e-1)" "unprognostic (1.41e-2)" "unprognostic (2.32e-2)" "unprognostic (1.57e-2)" "unprognostic (1.79e-2)" "unprognostic (1.76e-3)" "unprognostic (2.72e-3)" "unprognostic (2.85e-1)" "unprognostic (1.52e-1)" "unprognostic (2.70e-1)" "unprognostic (3.53e-3)" "unprognostic (1.81e-2)" "unprognostic (3.49e-2)" "unprognostic (2.59e-2)" "unprognostic (1.76e-2)" "unprognostic (6.49e-2)" "unprognostic (8.42e-2)" "unprognostic (1.05e-1)" "unprognostic (1.57e-1)" "unprognostic (2.84e-3)" "unprognostic (8.62e-2)" "unprognostic (4.43e-1)" "unprognostic (1.13e-1)" "unprognostic (2.15e-2)" "potential prognostic unfavorable (8.80e-4)" "unprognostic (1.78e-1)" "unprognostic (1.17e-1)" "unprognostic (3.21e-1)" TLDC2 "C20orf118, dJ132F21.2" ENSG00000101342 "TBC/LysM-associated domain containing 2" A0PJX2 20 36876121-36894235 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 17.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 21.0;cDC: 25.7;Colonocytes: 42.0;Enterocytes: 134.0;Epicardial cells: 29.6;Mast cells: 34.3;Renal collecting duct intercalated cells: 31.9;Schwann cells: 55.4;Tuft cells: 69.2" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 5.3;leukocyte: 3.6" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 17.9;Rectum Adenocarcinoma (TCGA): 19.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "basophil: 4.7" "Lineage enriched" "Detected in single" 6 "granulocytes: 4.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 9.9" "Kidney - Intercalated cells, Prostate - Fibroblasts" "Region enriched" "Detected in many" 4 "cerebellum: 5.7" "Low region specificity" "Detected in all" HPA047468 Enhanced NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 77: Intestine - Digestion" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 7 "HPA047468: " "potential prognostic favorable (8.64e-5)" "unprognostic (2.01e-1)" "unprognostic (3.05e-1)" "unprognostic (2.78e-1)" "unprognostic (4.24e-2)" "potential prognostic unfavorable (6.21e-4)" "unprognostic (1.83e-3)" "unprognostic (1.19e-2)" "potential prognostic unfavorable (5.88e-4)" "unprognostic (5.25e-2)" "unprognostic (3.76e-1)" "unprognostic (1.06e-1)" "unprognostic (2.12e-2)" "unprognostic (2.21e-3)" "unprognostic (1.51e-1)" "unprognostic (2.96e-1)" "unprognostic (8.96e-2)" "unprognostic (3.98e-1)" "unprognostic (3.69e-2)" "unprognostic (8.74e-2)" "unprognostic (4.16e-2)" "unprognostic (3.58e-2)" "unprognostic (1.48e-1)" "unprognostic (1.63e-1)" TLE1 "ESG, ESG1, GRG1, TLE-1" ENSG00000196781 "TLE family member 1, transcriptional corepressor" Q04724 9 81583683-81689547 "Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial glandular cells: 1133.3;Endometrial luminal cells: 576.3;Innate lymphoid cells: 491.7" "Cell type enhanced" "Detected in all" "fibroblast: 359.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Corticotropes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011482, HPA071396" Supported Supported Nucleoplasm NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 70: Non-specific - Protein processing" "Cluster 51: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 51: Secretory epithelial cells - Mixed function" 77 Nucleoplasm "CAB011482: , HPA071396: " "unprognostic (2.90e-1)" "unprognostic (1.73e-2)" "unprognostic (1.29e-1)" "unprognostic (3.33e-1)" "unprognostic (2.25e-1)" "unprognostic (2.22e-1)" "unprognostic (2.51e-1)" "unprognostic (6.63e-2)" "unprognostic (1.68e-1)" "unprognostic (5.95e-2)" "unprognostic (1.30e-2)" "unprognostic (2.77e-3)" "unprognostic (2.98e-1)" "unprognostic (1.15e-2)" "unprognostic (9.56e-2)" "potential prognostic unfavorable (2.60e-7)" "unprognostic (6.63e-2)" "unprognostic (7.76e-2)" "unprognostic (2.86e-2)" "unprognostic (7.95e-2)" "unprognostic (2.09e-1)" "unprognostic (1.48e-1)" "unprognostic (2.36e-1)" "unprognostic (5.19e-1)" "unprognostic (1.56e-2)" "unprognostic (2.29e-1)" "unprognostic (1.48e-1)" "unprognostic (6.68e-2)" "unprognostic (2.56e-2)" "unprognostic (1.34e-3)" "unprognostic (1.39e-1)" TLE2 "ESG, ESG2, FLJ41188, GRG2" ENSG00000065717 "TLE family member 2, transcriptional corepressor" Q04725 19 2997639-3047635 "Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 285.6" "Cell type enhanced" "Detected in many" "Oocytes: 179.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.7" "Group enriched" "Detected in many" 11 "B-cells: 1.7;T-cells: 1.2" "Cancer enhanced" "Detected in many" "Rhabdoid: 57.6" "Adrenal gland - Fibroblasts, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049103 Enhanced Supported "Nuclear bodies,Focal adhesion sites" NA NA "Cluster 64: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 39 "Nuclear bodies" "Focal adhesion sites" "HPA049103: " "potential prognostic favorable (5.53e-4)" "unprognostic (4.94e-3)" "unprognostic (2.42e-2)" "unprognostic (2.51e-1)" "unprognostic (1.91e-1)" "unprognostic (3.27e-2)" "unprognostic (1.64e-1)" "unprognostic (1.48e-1)" "unprognostic (9.26e-2)" "unprognostic (8.10e-2)" "unprognostic (1.88e-3)" "unprognostic (1.42e-3)" "unprognostic (1.27e-3)" "unprognostic (3.12e-2)" "potential prognostic favorable (2.79e-4)" "unprognostic (1.00e-2)" "unprognostic (3.30e-1)" "unprognostic (1.06e-1)" "unprognostic (4.58e-2)" "unprognostic (1.50e-2)" "unprognostic (4.68e-2)" "potential prognostic favorable (2.21e-6)" "unprognostic (1.81e-1)" "unprognostic (2.57e-1)" "unprognostic (2.20e-2)" "unprognostic (3.13e-3)" "unprognostic (3.61e-1)" "unprognostic (1.11e-1)" "unprognostic (1.12e-1)" "unprognostic (6.61e-2)" "unprognostic (5.57e-3)" TLE3 "ESG, ESG3, GRG3, HsT18976, KIAA1547" ENSG00000140332 "TLE family member 3, transcriptional corepressor" Q04726 15 70047790-70098176 "Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 61.6" "Cell type enriched" "Detected in many" 4 "Neutrophils: 595.7" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 91.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "neutrophil: 49.3" "Lineage enriched" "Detected in all" 5 "granulocytes: 49.3" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054116 Approved Supported Nucleoplasm,Cytosol NA Yes "Cluster 35: Neutrophils - Protein binding" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 41 Nucleoplasm Cytosol "HPA054116: " "unprognostic (3.90e-1)" "unprognostic (1.84e-1)" "unprognostic (1.12e-1)" "unprognostic (4.25e-2)" "unprognostic (2.76e-1)" "unprognostic (3.84e-2)" "unprognostic (1.79e-1)" "potential prognostic favorable (1.63e-4)" "unprognostic (8.91e-2)" "unprognostic (1.55e-1)" "potential prognostic favorable (8.32e-4)" "unprognostic (2.83e-2)" "unprognostic (1.09e-1)" "unprognostic (1.09e-2)" "potential prognostic unfavorable (2.81e-4)" "unprognostic (2.87e-1)" "unprognostic (2.23e-2)" "unprognostic (7.06e-2)" "unprognostic (1.88e-2)" "unprognostic (6.17e-3)" "unprognostic (1.80e-1)" "unprognostic (1.08e-1)" "unprognostic (1.02e-2)" "unprognostic (3.07e-2)" "unprognostic (1.73e-1)" "unprognostic (1.16e-1)" "unprognostic (1.82e-1)" "unprognostic (3.22e-1)" "unprognostic (3.55e-1)" "unprognostic (5.49e-2)" "unprognostic (3.98e-2)" TLE4 "E(spl), ESG, GRG4" ENSG00000106829 "TLE family member 4, transcriptional corepressor" Q04727 9 79571773-79726882 "Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 94.4" "Cell type enhanced" "Detected in all" "Early spermatids: 1051.1;Endometrial ciliated cells: 870.6;Lactotrophs: 1586.6;Late spermatids: 2003.5;Neutrophil progenitors: 901.6;Neutrophils: 1303.7" "Cell type enhanced" "Detected in all" "deep-layer corticothalamic and 6b: 902.4;deep-layer near-projecting: 904.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 22.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast myoepithelial cells, Pituitary gland - Lactotropes, Prostate - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065357 Supported Nucleoplasm,Mitochondria NA NA "Cluster 41: Basophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 14 Nucleoplasm Mitochondria "HPA065357: " "unprognostic (2.71e-2)" "unprognostic (8.74e-2)" "unprognostic (9.43e-2)" "unprognostic (8.24e-2)" "unprognostic (1.05e-3)" "unprognostic (1.82e-3)" "unprognostic (4.59e-1)" "unprognostic (3.74e-1)" "unprognostic (2.06e-1)" "unprognostic (2.46e-3)" "potential prognostic favorable (1.42e-4)" "unprognostic (6.70e-2)" "unprognostic (1.58e-3)" "unprognostic (8.82e-2)" "unprognostic (2.02e-3)" "unprognostic (1.98e-1)" "unprognostic (7.92e-2)" "unprognostic (1.25e-1)" "unprognostic (2.85e-1)" "unprognostic (5.05e-2)" "unprognostic (1.42e-1)" "unprognostic (7.38e-2)" "unprognostic (2.48e-1)" "unprognostic (1.53e-1)" "unprognostic (3.40e-1)" "unprognostic (2.46e-1)" "unprognostic (1.91e-1)" "unprognostic (4.43e-2)" "unprognostic (2.37e-1)" "unprognostic (1.28e-1)" "unprognostic (1.11e-1)" TLE5 "AES, GRG5" ENSG00000104964 "TLE family member 5, transcriptional modulator" Q08117 19 3052910-3063107 "Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 538.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049499 Approved Nucleoplasm NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 23: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 152 Nucleoplasm "HPA049499: " "unprognostic (2.56e-2)" "unprognostic (1.68e-1)" "potential prognostic favorable (7.45e-4)" "unprognostic (3.97e-2)" "unprognostic (2.21e-2)" "unprognostic (7.95e-2)" "unprognostic (2.99e-1)" "unprognostic (1.49e-3)" "unprognostic (1.03e-1)" "unprognostic (3.85e-3)" "unprognostic (1.17e-3)" "unprognostic (1.63e-2)" "unprognostic (6.59e-3)" "unprognostic (3.78e-3)" "unprognostic (3.35e-1)" "unprognostic (9.39e-2)" "unprognostic (3.67e-2)" "unprognostic (1.54e-1)" "unprognostic (3.44e-1)" "unprognostic (6.39e-3)" "unprognostic (3.38e-1)" "unprognostic (5.80e-2)" "unprognostic (3.37e-2)" "unprognostic (3.56e-2)" "unprognostic (2.52e-2)" "unprognostic (4.54e-3)" "unprognostic (1.87e-1)" "unprognostic (2.58e-1)" "unprognostic (4.38e-2)" TLE6 "FLJ14009, GRG6" ENSG00000104953 "TLE family member 6, subcortical maternal complex member" Q9H808 19 2977538-2995179 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 7.5" "Cell type enriched" "Detected in many" 6 "Oocytes: 138.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "NK-cell: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Spleen - Fibroblasts_2" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 33: Thyroid gland - Tissue development" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 41: Oocytes - Oogenesis" 2 "unprognostic (5.97e-2)" "unprognostic (8.39e-2)" "unprognostic (7.22e-2)" "unprognostic (9.87e-2)" "unprognostic (7.34e-3)" "unprognostic (1.82e-2)" "unprognostic (4.82e-2)" "unprognostic (2.49e-1)" "unprognostic (2.23e-1)" "unprognostic (2.13e-3)" "unprognostic (7.82e-2)" "unprognostic (5.32e-2)" "unprognostic (3.72e-3)" "unprognostic (8.19e-2)" "unprognostic (6.02e-2)" "unprognostic (6.15e-2)" "unprognostic (1.28e-1)" "unprognostic (1.14e-1)" "unprognostic (2.26e-1)" "unprognostic (1.50e-1)" "unprognostic (8.36e-2)" "unprognostic (2.46e-1)" "unprognostic (1.38e-1)" "unprognostic (2.35e-1)" "unprognostic (4.49e-2)" "unprognostic (2.08e-1)" "unprognostic (2.68e-1)" "unprognostic (1.40e-1)" "unprognostic (9.93e-2)" TLE7 ENSG00000260734 "TLE family member 7" A0A1W2PR48 16 71429980-71442054 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 10 "Oocytes: 55.3" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 13 "Testicular Germ Cell Tumor (TCGA): 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 72: Neuronal - Signal transduction" "Cluster 41: Oocytes - Oogenesis" "unprognostic (8.23e-2)" TLK1 "KIAA0137, PKU-BETA" ENSG00000198586 "Tousled like kinase 1" Q9UKI8 2 170990823-171231314 "Enzymes, Predicted intracellular proteins" "Cell cycle, DNA damage" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Platelets: 1024.7;Syncytiotrophoblasts: 720.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016043 Approved Supported Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 30 Nucleoplasm "HPA016043: " "unprognostic (1.81e-1)" "unprognostic (1.71e-3)" "unprognostic (2.41e-1)" "unprognostic (1.10e-1)" "unprognostic (2.71e-1)" "unprognostic (1.44e-1)" "unprognostic (1.24e-1)" "unprognostic (1.73e-1)" "unprognostic (1.18e-1)" "unprognostic (1.26e-1)" "potential prognostic favorable (5.53e-5)" "unprognostic (7.40e-2)" "unprognostic (2.45e-1)" "unprognostic (2.18e-2)" "unprognostic (8.94e-2)" "unprognostic (9.89e-2)" "unprognostic (9.25e-2)" "unprognostic (3.73e-3)" "unprognostic (2.05e-1)" "unprognostic (1.41e-1)" "unprognostic (5.16e-2)" "unprognostic (8.31e-2)" "unprognostic (3.44e-3)" "unprognostic (6.16e-2)" "unprognostic (1.45e-1)" "unprognostic (6.47e-2)" "unprognostic (4.82e-2)" "unprognostic (1.64e-1)" "unprognostic (2.47e-1)" "unprognostic (3.08e-2)" "unprognostic (2.83e-2)" TLK2 "MGC44450, PKU-ALPHA" ENSG00000146872 "Tousled like kinase 2" Q86UE8 17 62458658-62615481 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA damage" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 333.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056342 Supported Nucleoplasm,Nucleoli NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 40: Non-specific - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 7: Non-specific - Transcription" 42 Nucleoplasm Nucleoli "HPA056342: " "unprognostic (8.67e-3)" "unprognostic (7.74e-3)" "unprognostic (3.41e-2)" "unprognostic (1.40e-1)" "unprognostic (2.41e-1)" "unprognostic (6.14e-3)" "unprognostic (4.03e-1)" "potential prognostic favorable (4.81e-5)" "unprognostic (2.61e-1)" "unprognostic (1.76e-2)" "potential prognostic favorable (2.47e-4)" "unprognostic (7.20e-3)" "unprognostic (1.84e-1)" "unprognostic (1.24e-3)" "potential prognostic unfavorable (7.30e-5)" "unprognostic (5.91e-2)" "unprognostic (1.12e-2)" "unprognostic (6.03e-2)" "unprognostic (3.19e-2)" "unprognostic (2.59e-1)" "unprognostic (5.42e-2)" "unprognostic (8.28e-3)" "unprognostic (3.47e-2)" "unprognostic (1.03e-1)" "unprognostic (4.08e-2)" "unprognostic (3.94e-2)" "unprognostic (1.48e-1)" "unprognostic (8.16e-2)" "unprognostic (2.30e-1)" "unprognostic (3.99e-2)" "unprognostic (6.93e-2)" TLL1 ENSG00000038295 "Tolloid like 1" O43897 4 165873237-166104457 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Differentiation "Developmental protein, Hydrolase, Metalloprotease, Protease" "Atrial septal defect, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 6.4;placenta: 6.0" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 271.9;Corticotrophs: 364.3;Epicardial cells: 577.6;Leydig cells: 155.2;Lymphatic endothelial cells: 487.5;Oligodendrocyte progenitor cells: 127.9;Retinal bipolar cells: 181.4;Retinal ganglion cells: 301.3;Vascular endothelial cells: 353.8" "Cell type enhanced" "Detected in all" "hippocampal dentate gyrus: 961.0" "Cancer enhanced" "Detected in some" "Kidney Renal Clear Cell Carcinoma (TCGA): 3.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Minor Salivary Gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 9 "cerebellum: 56.6" HPA060767 Approved Vesicles "Secreted to extracellular matrix" "Developmental protein" NA NA 390000 "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 35: Non-specific - DNA binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" Vesicles "HPA060767: " "unprognostic (6.45e-2)" "unprognostic (9.52e-2)" "unprognostic (2.60e-2)" "unprognostic (1.18e-1)" "potential prognostic unfavorable (1.02e-4)" "validated prognostic favorable (1.01e-6)" "validated prognostic favorable (2.37e-7)" "unprognostic (4.13e-1)" "unprognostic (1.69e-1)" "unprognostic (8.63e-2)" "unprognostic (8.60e-3)" "unprognostic (2.50e-1)" TLL2 ENSG00000095587 "Tolloid like 2" Q9Y6L7 10 96364608-96513926 "Predicted secreted proteins" Differentiation "Developmental protein, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.5;heart muscle: 3.7;tongue: 1.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 16.9;Fibro-adipogenic progenitors: 18.1;Goblet cells: 26.7;Oligodendrocytes: 20.9;Pancreatic islet cells: 13.4;Pituitary stem cells: 23.6;Syncytiotrophoblasts: 17.4" "Cell type enhanced" "Detected in many" "oligodendrocyte: 32.7;splatter: 30.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Uterine cancer: 4.0" "Colon - Enteric glia cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted - unknown location" "Developmental protein" NA NA "Cluster 52: Non-specific - Cellular respiration" "Cluster 49: Hindbrain - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 70: Intestinal goblet cells - Mucin production" 8 "unprognostic (4.41e-2)" "unprognostic (1.97e-1)" TLN1 "ILWEQ, TLN" ENSG00000137076 "Talin 1" Q9Y490 9 35696948-35732195 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 345.2" "Group enriched" "Detected in many" 6 "Megakaryocytes: 2812.6;Platelets: 5578.5" "Cell type enhanced" "Detected in all" "vascular associated smooth muscle cell: 215.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002006, HPA004748" Supported Supported "Plasma membrane,Focal adhesion sites,Centriolar satellite,Cytosol" NA NA 1300000000 "Cluster 25: Non-specific - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 47: Platelets - Hemostasis" 42 "Focal adhesion sites, Cytosol" "Plasma membrane, Centriolar satellite" "CAB002006: , HPA004748: " "unprognostic (1.06e-1)" "unprognostic (2.23e-1)" "unprognostic (2.96e-1)" "potential prognostic unfavorable (7.71e-4)" "unprognostic (1.13e-1)" "unprognostic (4.83e-3)" "unprognostic (9.12e-2)" "unprognostic (5.58e-2)" "unprognostic (2.64e-1)" "unprognostic (4.84e-2)" "potential prognostic favorable (9.27e-7)" "unprognostic (1.35e-3)" "unprognostic (2.09e-2)" "unprognostic (2.76e-2)" "unprognostic (1.69e-2)" "unprognostic (1.15e-1)" "unprognostic (1.86e-3)" "unprognostic (1.76e-1)" "unprognostic (4.17e-1)" "unprognostic (3.27e-2)" "unprognostic (5.87e-2)" "unprognostic (4.00e-1)" "unprognostic (3.84e-1)" "unprognostic (8.88e-2)" "unprognostic (1.37e-1)" "unprognostic (2.94e-2)" "unprognostic (3.19e-1)" "unprognostic (2.68e-2)" "unprognostic (2.10e-2)" "unprognostic (2.61e-2)" "unprognostic (1.59e-1)" TLN2 "ILWEQ, KIAA0320" ENSG00000171914 "Talin 2" Q9Y4G6 15 62390526-62844631 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 35.3" "Cell type enhanced" "Detected in many" "Adipocytes: 1149.9;Choroid plexus epithelial cells: 1035.2;Ependymal cells: 714.4;Fibro-adipogenic progenitors: 475.0;Microglia: 570.4;Myosatellite cells: 715.8;Pituicytes/FSCs: 454.7;Proximal tubule cells: 458.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Spleen - Fibroblasts_2, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017194, HPA051828, HPA054787" Enhanced Supported "Focal adhesion sites,Cytosol" NA NA 45000000 "Cluster 72: Kidney - Transmembrane transport" "Cluster 53: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 89: Adipocytes - Lipid metabolism" 6 "Focal adhesion sites, Cytosol" "CAB017194: , HPA051828: , HPA054787: " "unprognostic (1.47e-1)" "potential prognostic favorable (1.77e-4)" "unprognostic (2.18e-2)" "unprognostic (1.73e-2)" "unprognostic (1.94e-1)" "unprognostic (1.62e-1)" "unprognostic (2.45e-1)" "unprognostic (9.67e-2)" "unprognostic (1.93e-1)" "unprognostic (1.57e-1)" "validated prognostic favorable (1.96e-11)" "validated prognostic favorable (1.46e-5)" "unprognostic (3.20e-3)" "unprognostic (5.35e-2)" "unprognostic (4.90e-1)" "unprognostic (6.06e-2)" "unprognostic (3.42e-2)" "unprognostic (2.96e-2)" "potential prognostic favorable (6.88e-4)" "unprognostic (1.59e-1)" "unprognostic (1.83e-2)" "unprognostic (4.66e-2)" "unprognostic (1.60e-1)" "unprognostic (2.33e-1)" "potential prognostic favorable (7.92e-4)" "unprognostic (2.25e-1)" "unprognostic (2.58e-2)" "unprognostic (7.55e-3)" "unprognostic (2.74e-1)" "unprognostic (9.21e-3)" "unprognostic (4.38e-2)" TLNRD1 "MESDC1, MGC99595" ENSG00000140406 "Talin rod domain containing 1" Q9H1K6 15 81000923-81005788 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 107.3;Urothelial cells: 86.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071716 Approved "Nucleoplasm,Cytoplasmic bodies" NA NA "Cluster 5: Spleen - Immune response" "Cluster 15: Non-specific - Transcription" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 4 "Nucleoplasm, Cytoplasmic bodies" "HPA071716: " "unprognostic (3.84e-2)" "unprognostic (2.39e-1)" "unprognostic (1.24e-3)" "unprognostic (4.14e-1)" "unprognostic (1.93e-1)" "potential prognostic unfavorable (8.93e-4)" "unprognostic (6.68e-2)" "unprognostic (1.17e-2)" "unprognostic (1.02e-1)" "unprognostic (5.51e-3)" "unprognostic (1.26e-2)" "unprognostic (5.21e-2)" "unprognostic (1.84e-3)" "potential prognostic unfavorable (6.63e-4)" "unprognostic (8.63e-3)" "unprognostic (1.69e-2)" "unprognostic (2.59e-1)" "unprognostic (8.66e-2)" "unprognostic (3.48e-2)" "unprognostic (2.43e-1)" "unprognostic (2.26e-1)" "unprognostic (1.51e-1)" "unprognostic (1.15e-1)" "unprognostic (4.41e-2)" "unprognostic (1.08e-1)" "unprognostic (2.65e-1)" "unprognostic (1.34e-1)" "unprognostic (5.79e-1)" "unprognostic (3.36e-2)" TLR1 "CD281, KIAA0012, rsc786" ENSG00000174125 "Toll like receptor 1" Q15399 4 38790677-38856817 "CD markers, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 32.4;lymphoid tissue: 25.4" "Cell type enhanced" "Detected in many" "cDC: 71.1;Kupffer cells: 159.9;Macrophages: 97.9;Microglia: 200.8;monocytes: 64.2;Neutrophil progenitors: 58.5;Neutrophils: 547.3;Salivary ionocytes: 58.3" "Cell type enriched" "Detected in many" 9 "central nervous system macrophage: 250.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 128.9" "Group enriched" "Detected in all" 6 "granulocytes: 128.9;monocytes: 43.0" "Cancer enhanced" "Detected in many" "lymphoma: 9.1" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Colon - Macrophages, Lung - Neutrophils_2, Stomach - Macrophages, Thyroid gland - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 3 "unprognostic (5.78e-2)" "unprognostic (1.33e-1)" "unprognostic (3.86e-1)" "potential prognostic favorable (9.37e-4)" "unprognostic (7.09e-2)" "unprognostic (3.68e-1)" "unprognostic (1.17e-1)" "unprognostic (1.93e-2)" "unprognostic (7.51e-2)" "unprognostic (4.90e-2)" "unprognostic (3.59e-3)" "unprognostic (8.62e-2)" "unprognostic (4.82e-1)" "unprognostic (5.12e-2)" "unprognostic (3.47e-1)" "unprognostic (8.39e-2)" "unprognostic (2.17e-2)" "unprognostic (3.19e-1)" "unprognostic (1.14e-1)" "unprognostic (6.95e-2)" "unprognostic (9.27e-2)" "unprognostic (5.17e-2)" "unprognostic (3.36e-1)" "unprognostic (1.98e-1)" "unprognostic (2.52e-2)" "unprognostic (3.24e-1)" "unprognostic (1.41e-1)" "unprognostic (1.63e-2)" "unprognostic (4.17e-3)" "unprognostic (3.69e-1)" "unprognostic (1.04e-1)" TLR10 CD290 ENSG00000174123 "Toll like receptor 10" Q9BXR5 4 38772238-38782990 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 44.9" "Group enriched" "Detected in some" 4 "B-cells: 68.4;Microglia: 92.3;Neutrophils: 74.9" "Cell type enriched" "Detected in some" 7 "central nervous system macrophage: 104.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 39.1;naive B-cell: 24.1" "Lineage enriched" "Detected in many" 5 "B-cells: 39.1" "Cancer enriched" "Detected in some" 4 "lymphoma: 27.2" "Adipose visceral - Neutrophils, Prostate - T-cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in many" HPA001940 Approved "Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 4 "Plasma membrane" "Endoplasmic reticulum" "HPA001940: " "potential prognostic favorable (2.61e-4)" "unprognostic (6.87e-2)" "unprognostic (2.77e-2)" "unprognostic (1.62e-1)" "unprognostic (3.29e-3)" "unprognostic (1.75e-1)" "unprognostic (2.44e-2)" "potential prognostic favorable (1.04e-4)" "unprognostic (1.75e-1)" "unprognostic (2.23e-1)" "unprognostic (1.29e-1)" "unprognostic (1.24e-1)" "unprognostic (1.20e-2)" "unprognostic (3.12e-2)" "unprognostic (2.25e-1)" "unprognostic (4.53e-2)" TLR2 "CD282, TIL4" ENSG00000137462 "Toll like receptor 2" O60603 4 153684070-153706260 "CD markers, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 66.0" "Cell type enriched" "Detected in many" 5 "Neutrophils: 3164.5" "Cell type enriched" "Detected in some" 5 "central nervous system macrophage: 299.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 200.3;intermediate monocyte: 179.4;myeloid DC: 121.5;neutrophil: 460.9;non-classical monocyte: 122.1" "Group enriched" "Detected in all" 48 "dendritic cells: 121.5;granulocytes: 460.9;monocytes: 200.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 11.0;Leukemia: 10.6" "Adipose subcutaneous - Macrophages, Adrenal gland - Macrophages, Kidney - Macrophages, Liver - Neutrophils, Lung - Neutrophils_2, Minor Salivary Gland - Minor salivary glandular cells, Spleen - Neutrophils_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA078321 Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 14 "Plasma membrane" "Nucleoplasm, Vesicles, Cytosol" "HPA078321: " "unprognostic (1.11e-1)" "unprognostic (1.35e-1)" "unprognostic (1.12e-1)" "unprognostic (7.84e-2)" "unprognostic (2.17e-1)" "unprognostic (3.22e-1)" "unprognostic (6.40e-2)" "unprognostic (3.80e-1)" "unprognostic (1.38e-2)" "unprognostic (1.39e-1)" "unprognostic (8.77e-3)" "unprognostic (1.72e-1)" "unprognostic (1.08e-2)" "unprognostic (2.05e-2)" "unprognostic (3.58e-3)" "potential prognostic favorable (5.70e-4)" "unprognostic (6.79e-2)" "unprognostic (2.18e-1)" "unprognostic (3.61e-2)" "unprognostic (5.71e-2)" "unprognostic (2.39e-1)" "unprognostic (4.22e-1)" "unprognostic (4.37e-3)" "unprognostic (3.10e-1)" "unprognostic (1.57e-1)" "unprognostic (1.14e-3)" "unprognostic (2.19e-1)" "unprognostic (1.27e-2)" "unprognostic (7.73e-2)" "unprognostic (9.89e-2)" "unprognostic (4.35e-1)" TLR3 CD283 ENSG00000164342 "Toll like receptor 3" O15455 4 186068911-186088073 "CD markers, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" "Receptor, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 28.2;Early spermatids: 101.7;Endometrial glandular cells: 26.1;Foveolar cells: 30.3;Microglia: 28.6;Syncytiotrophoblasts: 28.5" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 37.6;fibroblast: 9.6" "Cancer enriched" "Detected in all" 5 "Kidney Renal Clear Cell Carcinoma (TCGA): 44.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.9;memory CD8 T-cell: 3.1" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Kidney cancer: 12.1" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025658 Enhanced NA NA "Cluster 1: T-cells - Unknown function" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 12 "CAB025658: " "unprognostic (1.49e-2)" "unprognostic (1.71e-1)" "unprognostic (2.11e-1)" "unprognostic (3.31e-2)" "unprognostic (5.94e-2)" "unprognostic (1.78e-1)" "unprognostic (1.15e-1)" "unprognostic (1.28e-1)" "unprognostic (6.41e-2)" "unprognostic (1.96e-1)" "validated prognostic favorable (1.98e-11)" "validated prognostic favorable (1.77e-4)" "unprognostic (3.90e-2)" "unprognostic (1.28e-2)" "unprognostic (7.67e-3)" "unprognostic (4.42e-2)" "unprognostic (2.64e-2)" "unprognostic (1.12e-2)" "unprognostic (2.24e-1)" "unprognostic (4.04e-2)" "unprognostic (2.02e-1)" "potential prognostic unfavorable (6.16e-4)" "unprognostic (4.29e-1)" "unprognostic (1.22e-1)" "unprognostic (2.11e-2)" "unprognostic (1.88e-1)" "unprognostic (2.41e-1)" "unprognostic (2.44e-1)" "unprognostic (6.02e-2)" "unprognostic (3.54e-2)" "unprognostic (1.91e-2)" TLR4 "ARMD10, CD284, hToll, TLR-4" ENSG00000136869 "Toll like receptor 4" O00206 9 117704175-117724735 "CD markers, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" Receptor "Age-related macular degeneration, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 1.0;Foveolar cells: 1.0;monocytes: 1.3;Neutrophils: 4.4" "Cell type enhanced" "Detected in single" "central nervous system macrophage: 1.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 86.8" "Group enriched" "Detected in many" 33 "dendritic cells: 22.4;granulocytes: 86.8;monocytes: 65.9" "Cancer enhanced" "Detected in many" "Brain cancer: 11.7" "Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Neutrophils_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004025, HPA049174" Approved Approved "Golgi apparatus,Plasma membrane" "Intracellular and membrane" Receptor NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 39: Astrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 25 "Golgi apparatus, Plasma membrane" "CAB004025: , HPA049174: " "unprognostic (1.71e-1)" "unprognostic (6.55e-2)" "unprognostic (1.07e-1)" "unprognostic (7.44e-2)" "unprognostic (2.56e-1)" "unprognostic (2.34e-1)" "unprognostic (2.87e-1)" "unprognostic (2.10e-2)" "unprognostic (9.23e-2)" "unprognostic (1.14e-1)" "potential prognostic favorable (1.51e-6)" "unprognostic (1.28e-2)" "unprognostic (9.68e-2)" "unprognostic (6.78e-2)" "unprognostic (2.14e-3)" "unprognostic (2.99e-3)" "unprognostic (5.26e-2)" "unprognostic (4.44e-3)" "unprognostic (2.25e-1)" "unprognostic (1.26e-2)" "unprognostic (2.79e-2)" "unprognostic (1.18e-1)" "unprognostic (3.08e-1)" "unprognostic (2.94e-1)" "unprognostic (8.41e-2)" "unprognostic (8.50e-2)" "unprognostic (3.01e-2)" "unprognostic (2.94e-2)" "unprognostic (2.27e-3)" "unprognostic (4.00e-3)" "unprognostic (5.86e-2)" TLR5 "FLJ10052, MGC126430, MGC126431, SLEB1, TIL3" ENSG00000187554 "Toll like receptor 5" O60602 1 223109404-223143248 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial luminal cells: 47.7;Macrophages: 46.3;Microglia: 75.6;Neutrophils: 253.1;Prostatic club cells: 47.7" "Cell type enriched" "Detected in many" 6 "central nervous system macrophage: 95.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "classical monocyte: 30.8;intermediate monocyte: 28.1;myeloid DC: 23.4;neutrophil: 25.4;non-classical monocyte: 12.5" "Group enriched" "Detected in many" 11 "dendritic cells: 23.4;granulocytes: 25.4;monocytes: 30.8" "Low cancer specificity" "Detected in some" "Adrenal gland - Macrophages, Prostate - Urothelial cells, Spleen - Neutrophils_2" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB009013 Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 24: Neutrophils - Innate immunity signal integration" "Golgi apparatus" "Nucleoplasm, Cytosol" "CAB009013: " "unprognostic (2.23e-1)" "unprognostic (1.70e-2)" "unprognostic (1.65e-2)" "unprognostic (2.76e-1)" "unprognostic (2.17e-1)" "unprognostic (7.26e-2)" "unprognostic (5.38e-2)" "unprognostic (3.91e-1)" "unprognostic (1.03e-1)" "unprognostic (4.08e-2)" "unprognostic (3.77e-1)" "unprognostic (2.24e-1)" "unprognostic (3.65e-2)" "unprognostic (4.43e-2)" "unprognostic (7.11e-2)" "unprognostic (6.13e-2)" "unprognostic (1.58e-1)" "unprognostic (1.13e-1)" "unprognostic (3.11e-1)" "unprognostic (2.16e-2)" "unprognostic (6.16e-3)" "unprognostic (2.98e-1)" "unprognostic (7.72e-3)" "unprognostic (4.90e-2)" "unprognostic (1.17e-1)" "potential prognostic unfavorable (8.98e-4)" "unprognostic (2.30e-2)" "unprognostic (2.62e-1)" "unprognostic (1.68e-1)" TLR6 CD286 ENSG00000174130 "Toll like receptor 6" Q9Y2C9 4 38822897-38856817 "CD markers, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 11.3" "Cell type enhanced" "Detected in some" "Kupffer cells: 1.0;Neutrophils: 1.9" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "neutrophil: 11.4" "Lineage enriched" "Detected in many" 5 "granulocytes: 11.4" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Skeletal muscle - Macrophages, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA062733 Approved "Endoplasmic reticulum" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 3 "Endoplasmic reticulum" "HPA062733: " "unprognostic (1.79e-1)" "unprognostic (1.85e-1)" "unprognostic (5.52e-3)" "unprognostic (3.04e-1)" "unprognostic (2.81e-1)" "unprognostic (2.48e-1)" "unprognostic (3.92e-2)" "unprognostic (4.19e-2)" "unprognostic (1.28e-2)" "unprognostic (6.26e-2)" "potential prognostic unfavorable (3.87e-4)" "unprognostic (4.01e-1)" "unprognostic (1.55e-2)" "unprognostic (9.01e-2)" "unprognostic (4.02e-2)" "unprognostic (4.49e-2)" "unprognostic (4.21e-2)" "potential prognostic unfavorable (4.13e-6)" "unprognostic (1.89e-1)" "unprognostic (2.80e-1)" "unprognostic (1.74e-2)" "unprognostic (1.68e-2)" TLR7 ENSG00000196664 "Toll like receptor 7" Q9NYK1 X 12867072-12890361 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Disease variant, FDA approved drug targets, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 6.0" "Cell type enhanced" "Detected in some" "B-cells: 7.8;cDC: 11.1;Hofbauer cells: 47.7;Macrophages: 29.3;Microglia: 59.8;monocytes: 16.1;pDCs: 66.5" "Cell type enriched" "Detected in some" 48 "central nervous system macrophage: 75.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 20.7" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 9 "Leukemia: 1.5;lymphoma: 6.1;Myeloma: 5.5" "Adrenal gland - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA059613 Supported NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 1 "HPA059613: " "unprognostic (2.56e-1)" "unprognostic (6.14e-2)" "unprognostic (3.30e-1)" "unprognostic (5.71e-2)" "unprognostic (6.24e-2)" "unprognostic (1.08e-1)" "unprognostic (1.15e-2)" "unprognostic (1.25e-1)" "unprognostic (5.63e-3)" "potential prognostic favorable (2.51e-4)" "unprognostic (8.69e-3)" "unprognostic (5.62e-2)" "unprognostic (1.79e-1)" "unprognostic (2.48e-1)" "unprognostic (1.79e-2)" "unprognostic (3.50e-1)" "unprognostic (2.19e-1)" "unprognostic (3.14e-2)" "unprognostic (9.96e-3)" "unprognostic (8.94e-3)" TLR8 "CD288, hTLR8" ENSG00000101916 "Toll like receptor 8" Q9NR97 X 12906620-12923169 "CD markers, Disease related genes, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lung: 10.0;lymphoid tissue: 15.8" "Cell type enriched" "Detected in some" 4 "Neutrophils: 337.5" "Group enriched" "Detected in some" 17 "central nervous system macrophage: 4.4;leukocyte: 3.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 73 "classical monocyte: 16.7;intermediate monocyte: 14.9;myeloid DC: 8.4;neutrophil: 27.6;non-classical monocyte: 15.7" "Group enriched" "Detected in many" 77 "dendritic cells: 8.4;granulocytes: 27.6;monocytes: 16.7" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Spleen - Neutrophils_2, Stomach - Macrophages, Thyroid gland - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA001608 Enhanced NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 1 "HPA001608: " "unprognostic (1.55e-1)" "unprognostic (1.97e-2)" "unprognostic (1.16e-1)" "unprognostic (1.37e-1)" "unprognostic (2.10e-1)" "unprognostic (3.53e-2)" "unprognostic (7.38e-3)" "unprognostic (3.54e-1)" "unprognostic (2.39e-2)" "unprognostic (1.03e-2)" "unprognostic (1.11e-1)" "unprognostic (1.64e-1)" "unprognostic (3.00e-1)" "unprognostic (1.41e-1)" "unprognostic (2.06e-1)" "unprognostic (1.71e-1)" "unprognostic (1.83e-1)" "unprognostic (3.98e-2)" TLR9 CD289 ENSG00000239732 "Toll like receptor 9" Q9NR96 3 52221080-52225645 "CD markers, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 5.6" "Cell type enriched" "Detected in some" 6 "Tuft cells: 23.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "cerebral cortex: 10.3" "Immune cell enriched" "Detected in some" 7 "plasmacytoid DC: 167.1" "Lineage enriched" "Detected in many" 7 "dendritic cells: 167.1" "Cancer enhanced" "Detected in some" "lymphoma: 16.6;Myeloma: 6.4" "Thyroid gland - T-cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 15: Non-specific - Transcription" "Cluster 55: Lymphoma - Immune response" "Cluster 95: Tuft cells - Chemosensory signaling" 2 "unprognostic (2.51e-2)" "unprognostic (3.30e-1)" "unprognostic (8.91e-3)" "unprognostic (1.04e-2)" "unprognostic (7.34e-2)" "unprognostic (1.46e-2)" TLX1 "HOX11, TCL3" ENSG00000107807 "T cell leukemia homeobox 1" P31314 10 101131300-101137789 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 31 "lymphoid tissue: 56.4;salivary gland: 15.6" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 1.8;Gastric progenitor cells: 1.3;Kupffer cells: 2.0;Salivary acinar cells: 5.1;Salivary basal cells: 8.6;Salivary duct cells: 10.6;Salivary ionocytes: 5.8;Salivary myoepithelial cells: 2.3;Suprabasal keratinocytes: 2.7" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 6.0" "Group enriched" "Detected in some" 19 "medulla oblongata: 2.2;pons: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 7.5;Rhabdoid: 5.2" "Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 5: Spleen - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 9 "unprognostic (1.07e-1)" "unprognostic (4.25e-2)" "unprognostic (5.59e-3)" "unprognostic (2.01e-2)" "potential prognostic unfavorable (2.67e-4)" "unprognostic (3.39e-1)" "unprognostic (2.16e-1)" "unprognostic (4.61e-2)" "unprognostic (5.36e-1)" "unprognostic (9.70e-2)" "unprognostic (3.97e-1)" "unprognostic (3.78e-1)" "unprognostic (2.89e-1)" "unprognostic (1.74e-1)" "unprognostic (2.08e-1)" TLX2 "Enx, HOX11L1, NCX" ENSG00000115297 "T cell leukemia homeobox 2" O43763 2 74513463-74517148 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 1.9;retina: 2.9" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 21.3;Cone photoreceptor cells: 4.1;Differentiating spermatogonia: 4.2;Early primary spermatocytes: 9.8;Rod photoreceptor cells: 7.8" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 43 "Neuroblastoma: 116.2" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA062254 Approved Nucleoplasm NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 79: Photoreceptor cells - Phototransduction" 13 Nucleoplasm "HPA062254: " "unprognostic (5.43e-2)" "unprognostic (2.01e-3)" "potential prognostic unfavorable (6.49e-4)" TLX3 "HOX11L2, RNX" ENSG00000164438 "T cell leukemia homeobox 3" O43711 5 171309248-171312139 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 79 "brain: 24.0" "Group enriched" "Detected in some" 5 "Brain excitatory neurons: 4.5;Extravillous trophoblasts: 10.7;Oocytes: 4.6" "Cell type enriched" "Detected in some" 4 "upper rhombic lip: 11.1" "Cancer enhanced" "Detected in some" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 2.8" "Group enriched" "Detected in some" 5 "cerebellum: 18.6;medulla oblongata: 5.0;spinal cord: 11.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 8.4" "Pituitary gland - Thyrotropes" "Region enriched" "Detected in single" 7 "cerebellum: 2.2" "Region enriched" "Detected in some" 9 "cerebellum: 16.8" "HPA030504, HPA060957, HPA069359" Enhanced Enhanced Nucleoplasm NA NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 59: Leukemia - T-cell receptor" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 76 Nucleoplasm "HPA030504: , HPA060957: , HPA069359: " "unprognostic (2.95e-1)" "unprognostic (2.75e-2)" "unprognostic (4.87e-2)" "unprognostic (3.20e-1)" "unprognostic (4.21e-2)" TM2D1 BBP ENSG00000162604 "TM2 domain containing 1" Q9BX74 1 61681046-61725423 "Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046058, HPA055621" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 61: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 37: Non-specific - mRNA processing" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 3 Nucleoplasm Vesicles "HPA046058: , HPA055621: " "unprognostic (3.96e-1)" "unprognostic (1.21e-1)" "unprognostic (1.27e-1)" "unprognostic (1.11e-2)" "unprognostic (1.63e-1)" "unprognostic (1.52e-2)" "unprognostic (1.85e-1)" "unprognostic (1.67e-1)" "unprognostic (4.73e-2)" "unprognostic (3.15e-3)" "potential prognostic favorable (1.33e-4)" "unprognostic (4.92e-2)" "unprognostic (7.02e-2)" "potential prognostic unfavorable (8.23e-9)" "unprognostic (3.16e-3)" "unprognostic (4.59e-2)" "unprognostic (2.29e-1)" "unprognostic (7.50e-3)" "unprognostic (2.67e-1)" "unprognostic (1.52e-1)" "unprognostic (7.73e-3)" "unprognostic (3.74e-1)" "unprognostic (2.30e-1)" "unprognostic (1.45e-2)" "unprognostic (1.75e-1)" "unprognostic (4.62e-1)" "unprognostic (1.55e-1)" "unprognostic (3.97e-2)" "unprognostic (2.37e-1)" "unprognostic (2.49e-1)" "unprognostic (5.80e-2)" TM2D2 BLP1 ENSG00000169490 "TM2 domain containing 2" Q9BX73 8 38988808-38996824 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 124.1;Hofbauer cells: 424.7;Platelets: 182.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047152, HPA050547" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 21: Non-specific - Metabolism" "Cluster 40: Non-specific - Unknown function" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 1 "Nucleoplasm, Vesicles, Plasma membrane" "HPA047152: , HPA050547: " "unprognostic (1.69e-1)" "potential prognostic unfavorable (3.70e-5)" "unprognostic (2.47e-1)" "unprognostic (3.03e-1)" "unprognostic (6.57e-3)" "unprognostic (1.66e-2)" "unprognostic (1.10e-3)" "unprognostic (2.50e-2)" "unprognostic (3.30e-1)" "unprognostic (1.64e-2)" "potential prognostic favorable (3.02e-6)" "unprognostic (1.15e-1)" "unprognostic (6.95e-2)" "unprognostic (1.97e-2)" "unprognostic (1.12e-1)" "unprognostic (6.45e-2)" "unprognostic (6.48e-2)" "unprognostic (2.14e-1)" "unprognostic (3.59e-3)" "unprognostic (9.87e-2)" "unprognostic (2.74e-2)" "unprognostic (1.46e-2)" "unprognostic (7.13e-2)" "unprognostic (3.65e-2)" "unprognostic (7.92e-2)" "unprognostic (5.77e-2)" "unprognostic (7.12e-2)" "unprognostic (1.06e-1)" "unprognostic (9.12e-2)" "unprognostic (3.19e-2)" "unprognostic (2.84e-1)" TM2D3 "BLP2, FLJ22604" ENSG00000184277 "TM2 domain containing 3" Q9BRN9 15 101621444-101652391 "Predicted intracellular proteins, Predicted membrane proteins" "Alzheimer disease, Amyloidosis, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 285.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054064 Uncertain Approved Nucleoplasm,Cytosol Yes No 27000 "Cluster 21: Neutrophils - Unknown function" "Cluster 36: Brain & Liver - Signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 98: Neurons - Neurotransmission & signaling" 31 Nucleoplasm Cytosol "HPA054064: " "unprognostic (2.74e-1)" "unprognostic (8.55e-2)" "potential prognostic favorable (1.60e-4)" "unprognostic (3.83e-1)" "unprognostic (4.11e-2)" "unprognostic (1.09e-1)" "unprognostic (9.13e-3)" "unprognostic (1.21e-2)" "unprognostic (3.60e-2)" "unprognostic (4.79e-1)" "unprognostic (2.65e-3)" "unprognostic (2.13e-2)" "unprognostic (5.17e-2)" "unprognostic (1.85e-1)" "unprognostic (1.52e-2)" "unprognostic (9.09e-2)" "unprognostic (1.01e-1)" "unprognostic (2.47e-2)" "unprognostic (9.92e-2)" "unprognostic (5.08e-2)" "unprognostic (1.38e-1)" "unprognostic (3.96e-2)" "unprognostic (5.59e-2)" "unprognostic (1.55e-1)" "unprognostic (9.14e-2)" "unprognostic (2.13e-1)" "unprognostic (1.75e-2)" "unprognostic (6.48e-2)" "unprognostic (1.95e-1)" "unprognostic (1.06e-1)" "unprognostic (2.42e-1)" TM4SF1 "L6, M3S1" ENSG00000169908 "Transmembrane 4 L six family member 1" P30408 3 149369022-149377692 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast secretory cells: 2209.3;Endometrial glandular cells: 2222.0;Endometrial luminal cells: 1266.9;Esophageal apical cells: 3676.8;Esophageal suprabasal cells: 1234.9;Ocular epithelial cells: 1577.4;Pancreatic acinar cells: 7870.8;Pancreatic duct cells: 1483.6;Vascular endothelial cells: 1180.3" "Group enriched" "Detected in some" 6 "endothelial cell: 244.0;fibroblast: 68.4;vascular associated smooth muscle cell: 82.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Mesothelial cells, Adrenal gland - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002760, HPA002823" Uncertain NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 1 "CAB002760: , HPA002823: " "unprognostic (1.39e-2)" "unprognostic (5.95e-2)" "unprognostic (3.41e-1)" "unprognostic (7.31e-3)" "unprognostic (3.59e-1)" "unprognostic (6.45e-2)" "unprognostic (4.68e-3)" "unprognostic (5.77e-2)" "unprognostic (2.29e-3)" "unprognostic (1.20e-2)" "unprognostic (1.55e-1)" "potential prognostic favorable (7.80e-4)" "unprognostic (7.95e-2)" "unprognostic (3.04e-3)" "unprognostic (7.75e-3)" "unprognostic (1.96e-3)" "unprognostic (2.98e-2)" "unprognostic (2.91e-1)" "unprognostic (4.90e-1)" "unprognostic (2.17e-1)" "unprognostic (1.35e-1)" "potential prognostic unfavorable (7.66e-4)" "unprognostic (1.95e-3)" "unprognostic (5.30e-1)" "unprognostic (1.27e-1)" "potential prognostic favorable (9.80e-4)" "unprognostic (2.94e-1)" "unprognostic (5.24e-2)" "unprognostic (1.42e-1)" "unprognostic (3.87e-1)" "unprognostic (6.90e-2)" TM4SF18 L6D ENSG00000163762 "Transmembrane 4 L six family member 18" Q96CE8 3 149318498-149334414 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 31.9" "Cell type enhanced" "Detected in some" "Breast hormone-responsive cells: 73.4;Breast secretory cells: 24.3;Epididymal efferent duct absorptive cells: 26.6;Lymphatic endothelial cells: 186.9;Pancreatic duct cells: 36.3;Retinal pigment epithelial cells: 21.3;Vascular endothelial cells: 153.0" "Cell type enriched" "Detected in some" 10 "endothelial cell: 219.3" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 69.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 89.0" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Colon - Endothelial cells" "Low region specificity" "Detected in many" "HPA058640, HPA069378" Approved Approved "Plasma membrane" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 30 "Plasma membrane" "HPA058640: , HPA069378: " "unprognostic (2.69e-1)" "unprognostic (1.48e-1)" "unprognostic (1.38e-1)" "unprognostic (6.31e-2)" "unprognostic (7.91e-2)" "unprognostic (2.05e-1)" "unprognostic (4.88e-2)" "unprognostic (4.55e-2)" "unprognostic (4.62e-2)" "unprognostic (9.59e-2)" "potential prognostic favorable (1.35e-10)" "unprognostic (2.67e-2)" "unprognostic (5.96e-3)" "unprognostic (1.60e-2)" "unprognostic (3.02e-2)" "unprognostic (1.53e-1)" "unprognostic (1.05e-2)" "unprognostic (2.46e-2)" "unprognostic (4.33e-2)" "unprognostic (1.43e-1)" "unprognostic (2.53e-2)" "unprognostic (4.62e-3)" "unprognostic (2.37e-3)" "unprognostic (1.59e-1)" "unprognostic (7.73e-2)" "unprognostic (2.26e-2)" "unprognostic (4.44e-3)" "unprognostic (1.00e-2)" "unprognostic (2.00e-1)" "unprognostic (4.64e-1)" "unprognostic (2.57e-3)" TM4SF19 ENSG00000145107 "Transmembrane 4 L six family member 19" Q96DZ7 3 196319342-196338503 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 5.8;testis: 4.3" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Head and Neck Squamous Cell Carcinoma (TCGA): 28.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "gdT-cell: 14.8;memory CD8 T-cell: 3.9;naive CD8 T-cell: 4.9" "Lineage enriched" "Detected in single" 19 "T-cells: 14.8" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Mitotic cells (Minor salivary gland)" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 39: Testis - Nuclear processes" "Cluster 11: White matter - Signal transduction" "Cluster 72: Neuronal - Signal transduction" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 32 "unprognostic (2.17e-1)" "unprognostic (4.37e-2)" "unprognostic (1.43e-1)" "unprognostic (4.10e-3)" "potential prognostic unfavorable (9.31e-4)" "unprognostic (1.48e-1)" "unprognostic (2.29e-2)" "unprognostic (1.73e-1)" "unprognostic (1.25e-1)" "potential prognostic unfavorable (3.43e-7)" "unprognostic (1.13e-1)" "unprognostic (2.82e-2)" "potential prognostic unfavorable (3.64e-5)" "unprognostic (8.39e-3)" "validated prognostic unfavorable (2.97e-4)" "validated prognostic unfavorable (9.36e-4)" "unprognostic (4.19e-2)" "unprognostic (1.78e-2)" "unprognostic (8.22e-2)" "unprognostic (2.18e-1)" "unprognostic (4.99e-2)" "unprognostic (2.55e-2)" "unprognostic (6.76e-3)" "unprognostic (2.47e-2)" "unprognostic (4.48e-2)" "unprognostic (7.39e-2)" "unprognostic (1.81e-3)" "unprognostic (2.08e-1)" "unprognostic (1.15e-1)" TM4SF20 "FLJ22800, TCCE518" ENSG00000168955 "Transmembrane 4 L six family member 20" Q53R12 2 227362038-227381995 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Autism spectrum disorder" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 76 "intestine: 251.2" "Group enriched" "Detected in some" 4 "Enterocytes: 796.4;Gastric progenitor cells: 271.7" "Low cell type specificity" "Detected in some" "Group enriched" "Detected in many" 5 "Colon Adenocarcinoma (TCGA): 7.6;Liver Hepatocellular Carcinoma (TCGA): 7.3;Pancreatic Adenocarcinoma (TCGA): 9.1;Rectum Adenocarcinoma (TCGA): 8.8;Stomach Adenocarcinoma (TCGA): 18.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 3.0;Gastric cancer: 2.0" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA051838, HPA063184, HPA065531" Uncertain Supported "Plasma membrane,Focal adhesion sites" NA NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 1: Enterocytes - Absorption and Digestion" 6 "Plasma membrane, Focal adhesion sites" "HPA051838: , HPA063184: , HPA065531: " "unprognostic (1.93e-1)" "unprognostic (3.05e-1)" "unprognostic (3.57e-1)" "unprognostic (1.19e-1)" "unprognostic (6.93e-2)" "unprognostic (5.78e-2)" "unprognostic (5.14e-2)" "unprognostic (3.36e-1)" "unprognostic (9.15e-3)" "unprognostic (1.04e-1)" "unprognostic (2.58e-1)" TM4SF4 il-TMP ENSG00000169903 "Transmembrane 4 L six family member 4" P48230 3 149474697-149503394 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "gallbladder: 888.2;intestine: 611.2;liver: 657.6" "Cell type enhanced" "Detected in some" "Cholangiocytes: 2006.8;Enterocytes: 115.5;Hepatocytes: 890.0;Neuroendocrine cells: 234.8;Pancreatic duct cells: 133.0;Pancreatic islet cells: 425.6" "Not detected" "Not detected" "Group enriched" "Detected in many" 9 "Liver Hepatocellular Carcinoma (TCGA): 516.4;Pancreatic Adenocarcinoma (TCGA): 314.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Bile duct cancer: 68.8;colorectal cancer: 35.5;Gastric cancer: 74.3;liver cancer: 79.3;pancreatic cancer: 37.8" "Colon - Colon enteroendocrine cells, Liver - Hepatocytes, Stomach - Gastric enteroendocrine cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA046430 Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 77: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 19 "Plasma membrane" Cytosol "HPA046430: " "unprognostic (1.58e-1)" "unprognostic (3.16e-1)" "unprognostic (3.15e-1)" "unprognostic (1.70e-2)" "unprognostic (2.50e-1)" "unprognostic (2.80e-2)" "unprognostic (2.72e-1)" "unprognostic (1.12e-1)" "unprognostic (4.13e-2)" "unprognostic (1.89e-3)" "unprognostic (2.09e-1)" "unprognostic (1.44e-1)" "unprognostic (4.68e-2)" "unprognostic (1.64e-1)" "unprognostic (2.55e-3)" "unprognostic (1.42e-1)" "unprognostic (5.63e-2)" "unprognostic (2.99e-2)" "unprognostic (1.03e-1)" TM4SF5 ENSG00000142484 "Transmembrane 4 L six family member 5" O14894 17 4771884-4783213 "Predicted membrane proteins, Transporters" "Cell cycle" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "intestine: 164.2;liver: 190.2" "Cell type enhanced" "Detected in some" "Enteric stem cells: 56.9;Enterocytes: 617.6;Foveolar cells: 116.8;Gastric progenitor cells: 203.8;Goblet cells: 177.3;Hepatocytes: 177.7;Neuroendocrine cells: 192.1;Paneth cells: 96.7;Tuft cells: 57.6" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 8 "Liver Hepatocellular Carcinoma (TCGA): 379.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 16.0;Gastric cancer: 17.2;liver cancer: 34.6" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in single" HPA055674 Uncertain "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 77: Intestine - Digestion" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 1: Enterocytes - Absorption and Digestion" 3 "Plasma membrane, Cell Junctions" Nucleoplasm "HPA055674: " "unprognostic (6.14e-2)" "unprognostic (7.17e-2)" "unprognostic (7.40e-2)" "potential prognostic favorable (3.46e-4)" "unprognostic (2.44e-3)" "unprognostic (1.20e-1)" "unprognostic (7.79e-2)" "unprognostic (6.95e-2)" "unprognostic (2.22e-1)" "unprognostic (4.87e-2)" "unprognostic (3.52e-2)" "unprognostic (4.00e-1)" "unprognostic (5.17e-2)" "unprognostic (2.04e-2)" "unprognostic (1.20e-1)" TM6SF1 ENSG00000136404 "Transmembrane 6 superfamily member 1" Q9BZW5 15 83107572-83144854 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 44.3" "Cell type enhanced" "Detected in many" "cDC: 59.9;Epicardial cells: 54.6;Hofbauer cells: 63.6;Kupffer cells: 62.5;Macrophages: 89.7;Megakaryocytes: 105.1;Microglia: 216.0;Myonuclei: 88.5;Neutrophil progenitors: 85.3;Neutrophils: 114.9;Platelets: 77.6;Vascular endothelial cells: 59.6" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 277.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 77.1;eosinophil: 196.3;neutrophil: 118.7" "Lineage enriched" "Detected in many" 6 "granulocytes: 196.3" "Group enriched" "Detected in many" 5 "Leukemia: 10.5;lymphoma: 9.0;Myeloma: 3.5" "Adrenal gland - Macrophages, Breast - Endothelial cells, Colon - Endothelial cells, Pancreas - Macrophages, Skeletal muscle - Skeletal myocytes, Spleen - Macrophages, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016051, HPA056857" Uncertain NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "HPA016051: , HPA056857: " "unprognostic (3.92e-3)" "unprognostic (1.23e-2)" "unprognostic (1.54e-2)" "unprognostic (3.01e-3)" "unprognostic (6.60e-2)" "unprognostic (3.89e-1)" "unprognostic (2.65e-1)" "unprognostic (1.68e-1)" "unprognostic (2.68e-1)" "unprognostic (2.42e-2)" "potential prognostic favorable (2.20e-4)" "unprognostic (1.20e-1)" "unprognostic (1.21e-1)" "unprognostic (1.63e-1)" "potential prognostic favorable (1.22e-4)" "unprognostic (2.28e-2)" "unprognostic (1.53e-1)" "unprognostic (5.15e-1)" "unprognostic (1.22e-2)" "unprognostic (1.76e-2)" "unprognostic (1.01e-1)" "unprognostic (4.02e-2)" "unprognostic (2.98e-1)" "unprognostic (9.40e-3)" "unprognostic (9.28e-3)" "unprognostic (1.52e-1)" "unprognostic (3.27e-3)" "unprognostic (3.53e-3)" "unprognostic (1.85e-2)" "unprognostic (5.08e-2)" TM6SF2 Lpr4 ENSG00000213996 "Transmembrane 6 superfamily member 2" Q9BZW4 19 19264364-19273391 "Human disease related genes, Predicted membrane proteins, Transporters" "Lipid metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 17 "intestine: 71.1;liver: 32.0" "Cell type enhanced" "Detected in some" "Bergmann glia: 1.5;Brain excitatory neurons: 1.2;Brain inhibitory neurons: 1.4;Enterocytes: 3.9;Oligodendrocyte progenitor cells: 3.8;Other brain neurons: 3.9;Proximal tubule cells: 10.3" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Liver Hepatocellular Carcinoma (TCGA): 12.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adrenal gland - Adrenal medulla cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Fibroblasts, Stomach - Gastric mucous cells" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA066026 Uncertain NA NA "Cluster 77: Intestine - Digestion" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 88: Proximal tubular cells - Transmembrane transport" 8 "HPA066026: " "unprognostic (5.30e-2)" "unprognostic (1.88e-2)" "unprognostic (2.48e-1)" "unprognostic (7.25e-2)" "potential prognostic favorable (5.03e-6)" "unprognostic (1.02e-1)" "unprognostic (7.06e-2)" "unprognostic (1.27e-2)" "unprognostic (1.21e-3)" "unprognostic (4.24e-3)" "unprognostic (4.66e-2)" "unprognostic (1.27e-1)" TM7SF2 "ANG1, DHCR14A, NET47" ENSG00000149809 "Transmembrane 7 superfamily member 2" O76062 11 65111845-65116384 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 243.0" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 171.4;Breast lactating cells: 264.6;Epididymal clear cells: 144.9;Esophageal apical cells: 509.0;Esophageal suprabasal cells: 198.2;Müller glia: 166.5;Parietal cells: 192.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 38.2" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "prostate cancer: 109.3" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Prostate - Prostate glandular cells, Skin - Keratinocyte (granular), Stomach - Parietal cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030691, HPA072704" Enhanced Supported "Endoplasmic reticulum,Vesicles" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 60: Prostate cancer - Unknown function" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 3 "Endoplasmic reticulum" Vesicles "HPA030691: , HPA072704: " "unprognostic (3.27e-1)" "unprognostic (7.51e-2)" "unprognostic (1.05e-1)" "unprognostic (3.35e-1)" "unprognostic (2.41e-1)" "unprognostic (1.06e-2)" "unprognostic (3.08e-2)" "unprognostic (2.04e-1)" "unprognostic (2.77e-1)" "unprognostic (2.11e-1)" "potential prognostic favorable (3.34e-5)" "unprognostic (7.12e-2)" "potential prognostic favorable (8.57e-5)" "unprognostic (7.45e-2)" "unprognostic (4.96e-2)" "unprognostic (2.28e-1)" "unprognostic (4.34e-2)" "unprognostic (2.89e-1)" "unprognostic (3.39e-1)" "unprognostic (1.04e-1)" "unprognostic (1.17e-1)" "unprognostic (2.43e-2)" "unprognostic (1.86e-1)" "unprognostic (9.77e-2)" "unprognostic (4.79e-1)" "unprognostic (6.39e-2)" "unprognostic (1.31e-2)" "unprognostic (1.96e-1)" "unprognostic (1.42e-1)" "unprognostic (7.06e-2)" "unprognostic (8.23e-2)" TM7SF3 ENSG00000064115 "Transmembrane 7 superfamily member 3" Q9NS93 12 26971579-27014434 "Predicted intracellular proteins, Predicted membrane proteins" "Stress response" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 239.2" "Cell type enhanced" "Detected in all" "Proximal tubule cells: 349.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Mitotic cells (Skin)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057640 Supported Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 12: Non-specific - Vasculature" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 37: Neutrophil progenitors - Granulopoiesis" Cytosol Nucleoplasm "HPA057640: " "unprognostic (9.77e-2)" "unprognostic (1.11e-1)" "unprognostic (7.36e-2)" "potential prognostic unfavorable (9.69e-4)" "unprognostic (6.53e-3)" "unprognostic (3.29e-2)" "unprognostic (1.80e-1)" "unprognostic (8.59e-2)" "unprognostic (7.65e-2)" "unprognostic (5.91e-3)" "potential prognostic favorable (5.84e-9)" "unprognostic (2.18e-2)" "unprognostic (2.00e-2)" "unprognostic (5.80e-2)" "unprognostic (1.25e-1)" "unprognostic (1.52e-1)" "unprognostic (5.86e-2)" "unprognostic (3.64e-1)" "unprognostic (3.83e-1)" "unprognostic (3.35e-2)" "unprognostic (1.62e-1)" "unprognostic (1.02e-3)" "unprognostic (4.67e-3)" "unprognostic (3.35e-1)" "unprognostic (3.09e-1)" "unprognostic (2.03e-1)" "unprognostic (2.05e-1)" "unprognostic (1.38e-1)" "unprognostic (2.69e-1)" "unprognostic (1.67e-1)" "unprognostic (1.41e-1)" TM9SF1 "HMP70, MP70" ENSG00000100926 "Transmembrane 9 superfamily member 1" O15321 14 24189149-24195687 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Astrocytes: 12.7;Bergmann glia: 16.1;Brain excitatory neurons: 8.5;Brain inhibitory neurons: 8.8;Choroid plexus epithelial cells: 9.7;Ependymal cells: 24.8;Microglia: 7.4;Oligodendrocyte progenitor cells: 12.3;Oligodendrocytes: 11.5;Other brain neurons: 10.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Colon - Macrophages, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059249 Supported Approved "Golgi apparatus" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 70: Non-specific - Protein processing" "Cluster 39: Astrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 98: Neurons - Neurotransmission & signaling" 22 "Golgi apparatus" "HPA059249: " "unprognostic (5.06e-2)" "unprognostic (2.58e-1)" "unprognostic (1.38e-1)" "unprognostic (3.15e-2)" "unprognostic (6.10e-3)" "unprognostic (1.15e-1)" "unprognostic (1.35e-1)" "unprognostic (7.28e-2)" "unprognostic (2.97e-2)" "unprognostic (6.87e-2)" "potential prognostic favorable (6.83e-6)" "unprognostic (1.71e-1)" "unprognostic (4.25e-2)" "unprognostic (1.88e-2)" "unprognostic (1.12e-1)" "unprognostic (1.50e-1)" "unprognostic (1.26e-2)" "unprognostic (4.07e-2)" "unprognostic (3.91e-1)" "unprognostic (4.33e-2)" "unprognostic (3.20e-1)" "unprognostic (6.04e-2)" "unprognostic (4.32e-1)" "unprognostic (2.97e-2)" "unprognostic (5.08e-2)" "unprognostic (1.32e-1)" "unprognostic (1.21e-1)" "unprognostic (1.39e-1)" "unprognostic (1.50e-1)" "unprognostic (8.43e-2)" "unprognostic (2.62e-1)" TM9SF2 P76 ENSG00000125304 "Transmembrane 9 superfamily member 2" Q99805 13 99446311-99564048 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Spleen - Macrophages, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005657 Supported NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 17: Intestine - Digestion" "Cluster 21: Non-specific - Metabolism" "Cluster 19: Non-specific - Unknown function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 19 "HPA005657: " "unprognostic (3.93e-3)" "unprognostic (4.03e-3)" "unprognostic (6.06e-2)" "unprognostic (1.03e-2)" "unprognostic (6.75e-2)" "unprognostic (5.04e-2)" "unprognostic (2.18e-1)" "unprognostic (1.37e-1)" "unprognostic (2.98e-3)" "unprognostic (5.56e-2)" "potential prognostic favorable (2.87e-8)" "unprognostic (8.06e-2)" "unprognostic (3.36e-3)" "unprognostic (6.26e-2)" "unprognostic (1.59e-1)" "unprognostic (2.49e-1)" "unprognostic (4.71e-3)" "unprognostic (8.69e-3)" "unprognostic (2.16e-1)" "unprognostic (6.20e-2)" "unprognostic (3.81e-2)" "unprognostic (1.63e-1)" "unprognostic (1.31e-1)" "unprognostic (1.39e-1)" "unprognostic (2.28e-1)" "unprognostic (1.06e-2)" "unprognostic (9.98e-2)" "unprognostic (6.24e-2)" "unprognostic (2.43e-1)" "unprognostic (6.62e-2)" "unprognostic (1.28e-2)" TM9SF3 SMBP ENSG00000077147 "Transmembrane 9 superfamily member 3" Q9HD45 10 96518110-96587452 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039609 Approved Approved "Golgi apparatus,Vesicles" NA NA 87000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 17: Intestine - Digestion" "Cluster 55: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 70: Intestinal goblet cells - Mucin production" 33 Vesicles "Golgi apparatus" "HPA039609: " "unprognostic (5.66e-2)" "unprognostic (2.68e-2)" "unprognostic (3.15e-2)" "unprognostic (1.14e-2)" "unprognostic (7.36e-3)" "unprognostic (6.73e-2)" "unprognostic (2.13e-1)" "unprognostic (1.11e-1)" "unprognostic (1.27e-1)" "unprognostic (3.10e-2)" "potential prognostic favorable (6.34e-7)" "unprognostic (6.03e-2)" "unprognostic (1.46e-2)" "unprognostic (2.86e-2)" "unprognostic (7.90e-3)" "unprognostic (2.36e-3)" "unprognostic (1.07e-1)" "unprognostic (6.23e-2)" "unprognostic (1.18e-2)" "unprognostic (9.42e-3)" "potential prognostic unfavorable (1.08e-5)" "unprognostic (5.33e-3)" "unprognostic (1.22e-1)" "unprognostic (9.71e-2)" "unprognostic (1.04e-1)" "unprognostic (7.40e-3)" "unprognostic (2.64e-1)" "unprognostic (8.78e-2)" "unprognostic (1.11e-1)" "unprognostic (1.90e-2)" "unprognostic (1.57e-1)" TM9SF4 "dJ836N17.2, KIAA0255" ENSG00000101337 "Transmembrane 9 superfamily member 4" Q92544 20 32109714-32167258 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064099 Approved NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 40 "HPA064099: " "unprognostic (1.05e-1)" "unprognostic (7.33e-3)" "unprognostic (3.27e-1)" "unprognostic (2.53e-2)" "unprognostic (3.07e-1)" "unprognostic (1.74e-1)" "unprognostic (3.63e-1)" "unprognostic (3.31e-2)" "unprognostic (1.50e-1)" "unprognostic (1.76e-2)" "unprognostic (6.50e-3)" "unprognostic (2.91e-2)" "unprognostic (2.47e-2)" "potential prognostic unfavorable (6.82e-4)" "unprognostic (2.26e-3)" "unprognostic (3.08e-2)" "potential prognostic unfavorable (2.89e-4)" "unprognostic (4.29e-2)" "unprognostic (2.00e-1)" "unprognostic (8.65e-2)" "unprognostic (7.50e-3)" "unprognostic (8.31e-2)" "unprognostic (4.12e-2)" "unprognostic (2.67e-2)" "unprognostic (4.43e-3)" "unprognostic (1.59e-1)" "unprognostic (3.04e-1)" "unprognostic (1.16e-2)" "unprognostic (2.47e-1)" "unprognostic (2.29e-1)" "unprognostic (1.36e-1)" TMA16 "C4orf43, FLJ11184" ENSG00000198498 "Translation machinery associated 16 homolog" Q96EY4 4 163494442-163520539 "Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 160.5;Late primary spermatocytes: 227.5;Late spermatids: 252.1;Megakaryocytes: 160.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041571, HPA052688" Uncertain Enhanced Nucleoplasm,Nucleoli NA NA 12000 "Cluster 13: Non-specific - Mitochondria" "Cluster 39: Testis - Nuclear processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 17: Non-specific - RNA processing" 16 Nucleoli Nucleoplasm "HPA041571: , HPA052688: " "unprognostic (4.39e-2)" "unprognostic (7.62e-2)" "unprognostic (1.18e-2)" "unprognostic (3.69e-1)" "unprognostic (3.76e-3)" "unprognostic (3.80e-1)" "unprognostic (2.19e-1)" "unprognostic (1.40e-2)" "potential prognostic unfavorable (5.66e-4)" "unprognostic (1.24e-3)" "unprognostic (5.06e-2)" "unprognostic (1.45e-1)" "potential prognostic unfavorable (8.46e-4)" "validated prognostic unfavorable (1.07e-5)" "validated prognostic unfavorable (2.18e-5)" "unprognostic (2.87e-1)" "unprognostic (8.90e-2)" "unprognostic (2.08e-1)" "unprognostic (7.45e-2)" "potential prognostic unfavorable (1.74e-4)" "unprognostic (7.64e-3)" "unprognostic (5.69e-3)" "unprognostic (2.08e-2)" "unprognostic (2.82e-1)" "unprognostic (2.36e-2)" "unprognostic (2.23e-1)" "unprognostic (1.74e-1)" "unprognostic (4.16e-2)" "unprognostic (2.83e-2)" TMA7 "CCDC72, HSPC016" ENSG00000232112 "Translation machinery associated 7 homolog" Q9Y2S6 3 48440257-48444208 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 1589.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047397 Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Nuclear bodies" Yes No "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 15: Non-specific - Protein processing" 1 "Nucleoli, Nucleoli rim" "Nucleoplasm, Nuclear bodies" "HPA047397: " "unprognostic (3.73e-2)" "unprognostic (3.82e-2)" "unprognostic (4.97e-2)" "unprognostic (1.69e-1)" "unprognostic (1.34e-2)" "unprognostic (2.26e-1)" "unprognostic (7.14e-2)" "unprognostic (2.41e-2)" "potential prognostic unfavorable (4.51e-4)" "unprognostic (6.50e-3)" "unprognostic (5.69e-2)" "unprognostic (3.15e-2)" "unprognostic (6.93e-3)" "unprognostic (1.35e-1)" "unprognostic (1.04e-1)" "potential prognostic favorable (1.62e-4)" "unprognostic (6.30e-2)" "unprognostic (3.18e-3)" "unprognostic (1.95e-1)" "unprognostic (4.70e-2)" "unprognostic (4.31e-1)" "unprognostic (1.60e-2)" "unprognostic (9.84e-2)" "unprognostic (3.97e-2)" "unprognostic (3.29e-2)" "unprognostic (2.13e-2)" "unprognostic (2.17e-2)" "unprognostic (1.84e-1)" "unprognostic (7.63e-2)" TMBIM1 "LFG3, PP1201, RECS1" ENSG00000135926 "Transmembrane BAX inhibitor motif containing 1" Q969X1 2 218274197-218292586 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 291.6;Esophageal apical cells: 1555.8;Esophageal suprabasal cells: 409.0;Pancreatic acinar cells: 351.3;Platelets: 633.8;Syncytiotrophoblasts: 368.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012093, HPA070824" Approved Supported Vesicles NA NA 14000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 84: Apical squamous epithelium - Cornification" 7 Vesicles "HPA012093: , HPA070824: " "unprognostic (5.65e-2)" "unprognostic (1.82e-2)" "unprognostic (2.74e-1)" "unprognostic (1.02e-1)" "unprognostic (1.67e-1)" "unprognostic (2.66e-2)" "unprognostic (7.71e-3)" "potential prognostic unfavorable (4.61e-6)" "unprognostic (2.89e-2)" "unprognostic (1.72e-1)" "validated prognostic favorable (6.97e-11)" "validated prognostic favorable (9.38e-4)" "unprognostic (2.55e-1)" "unprognostic (1.92e-3)" "unprognostic (2.37e-2)" "unprognostic (1.76e-2)" "unprognostic (3.57e-1)" "unprognostic (4.34e-2)" "unprognostic (2.67e-3)" "unprognostic (1.34e-2)" "unprognostic (1.36e-1)" "unprognostic (3.45e-3)" "unprognostic (1.20e-1)" "unprognostic (2.12e-1)" "unprognostic (3.90e-1)" "unprognostic (7.18e-2)" "unprognostic (1.22e-1)" "unprognostic (9.79e-2)" "unprognostic (2.40e-1)" "unprognostic (1.61e-1)" "unprognostic (1.37e-1)" TMBIM4 "CGI-119, GAAP, LFG4, S1R, ZPRO" ENSG00000155957 "Transmembrane BAX inhibitor motif containing 4" Q9HC24 12 66135846-66170027 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 279.5;Gastric chief cells: 364.7;Late primary spermatocytes: 806.4;Parietal cells: 392.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077642 Supported "Golgi apparatus" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 61: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 38: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" "Golgi apparatus" "HPA077642: " "unprognostic (2.98e-2)" "unprognostic (5.37e-2)" "unprognostic (3.67e-2)" "unprognostic (1.64e-3)" "unprognostic (8.13e-3)" "unprognostic (2.27e-3)" "unprognostic (1.23e-2)" "unprognostic (1.05e-3)" "unprognostic (1.04e-1)" "unprognostic (8.05e-3)" "potential prognostic favorable (1.68e-7)" "unprognostic (2.50e-1)" "unprognostic (1.63e-1)" "unprognostic (2.21e-1)" "unprognostic (1.22e-1)" "unprognostic (2.91e-1)" "unprognostic (4.50e-1)" "unprognostic (1.59e-2)" "unprognostic (4.66e-3)" "unprognostic (1.19e-1)" "unprognostic (1.59e-2)" "unprognostic (2.93e-2)" "unprognostic (3.28e-2)" "unprognostic (2.06e-1)" "unprognostic (8.64e-2)" "unprognostic (4.35e-1)" "unprognostic (5.42e-2)" "unprognostic (7.88e-2)" "unprognostic (1.58e-1)" "unprognostic (1.47e-1)" "unprognostic (1.21e-1)" TMBIM6 "BAXI1, BI-1, TEGT" ENSG00000139644 "Transmembrane BAX inhibitor motif containing 6" P55061 12 49707725-49764934 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Autophagy, Unfolded protein response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1685.6" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 2842.8;Hepatocytes: 2811.4;Late spermatids: 3972.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Spleen - Macrophages, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017378 Approved NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 93: Hepatocytes - Bile production & excretion" 74 "HPA017378: " "unprognostic (1.69e-2)" "potential prognostic unfavorable (4.47e-4)" "unprognostic (2.81e-2)" "unprognostic (2.61e-3)" "unprognostic (1.72e-2)" "unprognostic (1.14e-1)" "unprognostic (1.13e-1)" "unprognostic (3.55e-3)" "potential prognostic unfavorable (4.65e-4)" "unprognostic (4.35e-2)" "potential prognostic favorable (1.72e-8)" "unprognostic (4.56e-2)" "unprognostic (2.72e-1)" "unprognostic (2.15e-1)" "unprognostic (1.80e-1)" "unprognostic (2.24e-2)" "unprognostic (2.05e-1)" "unprognostic (5.90e-2)" "unprognostic (5.83e-3)" "unprognostic (1.37e-1)" "unprognostic (9.54e-2)" "unprognostic (9.44e-2)" "unprognostic (1.44e-1)" "unprognostic (1.08e-1)" "unprognostic (2.08e-1)" "unprognostic (1.25e-1)" "unprognostic (6.89e-2)" "unprognostic (3.17e-1)" "unprognostic (6.33e-2)" "unprognostic (1.70e-1)" "unprognostic (3.34e-1)" TMC1 "DFNA36, DFNB11, DFNB7" ENSG00000165091 "Transmembrane channel like 1" Q8TDI8 9 72521608-72838297 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Hearing, Ion transport, Transport" "Ion channel" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.1;cervix: 1.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 145.0;Esophageal apical cells: 316.0;Extravillous trophoblasts: 94.6;Migrating cytotrophoblasts: 100.8;Podocytes: 95.8;Prostatic club cells: 99.6;Prostatic hillock cells: 82.4;Proximal tubule cells: 245.7;Syncytiotrophoblasts: 81.9;Urothelial cells: 318.1" "Cell type enhanced" "Detected in many" "astrocyte: 48.1;Bergmann glia: 61.2;endothelial cell: 33.4;ependymal cell: 34.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 27: Non-specific - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 69: Urothelial cells - Basic cellular functions" "unprognostic (2.81e-1)" TMC2 "C20orf145, dJ686C3.3" ENSG00000149488 "Transmembrane channel like 2" Q8TDI7 20 2536573-2643580 "Predicted membrane proteins" "Ion transport, Transport" "Ion channel" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 2.7" "Cell type enriched" "Detected in some" 6 "Somatotrophs: 320.2" "Cell type enhanced" "Detected in many" "hippocampal dentate gyrus: 45.3;oligodendrocyte precursor cell: 41.5;upper rhombic lip: 52.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 64: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" TMC3 ENSG00000188869 "Transmembrane channel like 3" Q7Z5M5 15 81331088-81374213 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 51 "parathyroid gland: 78.6" "Cell type enriched" "Detected in some" 4 "Epicardial cells: 34.1" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA040265, HPA040510" Enhanced Supported Cytosol NA NA "Cluster 69: Parathyroid gland - Mixed function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" Cytosol "HPA040265: , HPA040510: " "unprognostic (4.90e-2)" "unprognostic (1.06e-1)" "unprognostic (2.62e-1)" "unprognostic (4.55e-2)" TMC4 ENSG00000167608 "Transmembrane channel like 4" 19 54160108-54173250 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "pancreas: 43.1" "Cell type enhanced" "Detected in many" "Colonocytes: 51.9;Distal convoluted tubule cells: 46.0;Enterocytes: 63.0;Fallopian tube ciliated cells: 45.0;Foveolar cells: 43.0;Loop of henle epithelial cells: 51.2;Papillary tip epithelial cells: 66.8;Parietal cells: 60.1;Renal collecting duct intercalated cells: 51.9;Renal collecting duct principal cells: 60.7;Renal connecting tubule cells: 55.6" "Group enriched" "Detected in many" 7 "ependymal cell: 20.2;pericyte: 29.8;vascular associated smooth muscle cell: 18.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Liver - Cholangiocytes, Lung - Alveolar cells type 2, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA048635 Approved Approved Vesicles NA NA "Cluster 60: Stomach - Digestion" "Cluster 46: Brainstem - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" Vesicles "HPA048635: " "unprognostic (8.63e-2)" "unprognostic (1.22e-1)" "unprognostic (3.20e-1)" "unprognostic (7.14e-3)" "unprognostic (2.47e-1)" "unprognostic (2.08e-1)" "unprognostic (3.04e-1)" "unprognostic (3.24e-2)" "unprognostic (1.91e-1)" "unprognostic (5.48e-2)" "unprognostic (1.25e-1)" "unprognostic (2.42e-1)" "unprognostic (1.01e-1)" "unprognostic (1.80e-1)" "unprognostic (5.75e-2)" "unprognostic (5.99e-2)" "unprognostic (2.77e-1)" "unprognostic (8.90e-2)" "unprognostic (1.06e-1)" "unprognostic (6.33e-2)" "unprognostic (7.22e-2)" "unprognostic (3.69e-2)" "unprognostic (1.24e-1)" "unprognostic (3.51e-3)" "unprognostic (1.07e-1)" "unprognostic (1.35e-1)" "unprognostic (2.78e-1)" TMC5 FLJ13593 ENSG00000103534 "Transmembrane channel like 5" Q6UXY8 16 19410496-19499113 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 50.3;stomach 1: 43.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 374.1;Alveolar cells type 2: 316.0;Conjunctival goblet cells: 458.2;Endometrial glandular cells: 348.2;Enterocytes: 862.7;Foveolar cells: 483.3;Mucous neck cells: 424.1;Respiratory ciliated cells: 975.8;Respiratory deuterosomal cells: 507.9;Respiratory secretory cells: 389.5;Submucosal glandular cells: 324.5;Transitional alveolar cells: 419.3" "Cell type enriched" "Detected in many" 4 "choroid plexus epithelial cell: 50.9" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 6 "choroid plexus: 13.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 32.0;Gastric cancer: 35.0" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA040810, HPA042037" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 77: Intestine - Digestion" "Cluster 36: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 38: Secretory epithelial cells - Exocrine secretion" "Plasma membrane" Nucleoplasm "HPA040810: , HPA042037: " "unprognostic (1.85e-1)" "unprognostic (1.18e-1)" "unprognostic (1.49e-1)" "unprognostic (4.02e-1)" "unprognostic (2.17e-2)" "unprognostic (1.62e-1)" "unprognostic (2.84e-2)" "unprognostic (1.56e-2)" "unprognostic (3.83e-1)" "potential prognostic unfavorable (3.21e-4)" "unprognostic (1.11e-1)" "unprognostic (2.04e-3)" "unprognostic (8.26e-2)" "unprognostic (1.21e-2)" "unprognostic (3.06e-2)" "unprognostic (6.63e-2)" "unprognostic (1.85e-1)" "unprognostic (2.79e-2)" "unprognostic (2.72e-1)" "unprognostic (7.75e-2)" "unprognostic (6.36e-2)" "unprognostic (2.02e-1)" "unprognostic (1.94e-1)" "unprognostic (3.78e-1)" "unprognostic (2.72e-2)" TMC6 "EVER1, EVIN1, LAK-4P, TNRC6C-AS1" ENSG00000141524 "Transmembrane channel like 6" Q7Z403 17 78107397-78132407 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 51.3;lymphoid tissue: 72.3" "Cell type enhanced" "Detected in many" "B-cells: 101.7;Breast lactating cells: 97.5;Hofbauer cells: 98.8;Kupffer cells: 156.8;NK-cells: 94.2;Oligodendrocytes: 104.1;T-cells: 95.4" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 83.5;leukocyte: 156.7;oligodendrocyte: 133.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Liver - Kupffer cells, Minor Salivary Gland - Minor salivary glandular cells, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051430 Uncertain NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 5: Spleen - Immune response" "Cluster 30: White matter - Myelination" "Cluster 47: Leukemia - Hemostasis" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 18 "HPA051430: " "unprognostic (1.01e-2)" "unprognostic (1.25e-1)" "unprognostic (1.98e-1)" "unprognostic (1.16e-1)" "unprognostic (7.68e-2)" "unprognostic (1.89e-1)" "unprognostic (2.58e-1)" "unprognostic (4.57e-2)" "unprognostic (2.63e-2)" "unprognostic (3.23e-1)" "unprognostic (3.63e-1)" "unprognostic (9.82e-2)" "unprognostic (3.09e-1)" "unprognostic (8.43e-2)" "unprognostic (1.03e-1)" "unprognostic (1.20e-1)" "unprognostic (2.83e-1)" "unprognostic (4.41e-2)" "unprognostic (2.58e-1)" "unprognostic (6.07e-2)" "unprognostic (1.21e-1)" "unprognostic (1.88e-1)" "unprognostic (3.32e-2)" "unprognostic (2.59e-1)" "unprognostic (1.33e-1)" "unprognostic (3.99e-1)" "unprognostic (1.04e-1)" "unprognostic (1.51e-2)" "unprognostic (6.85e-2)" "unprognostic (2.06e-2)" "unprognostic (1.24e-1)" TMC7 FLJ21240 ENSG00000170537 "Transmembrane channel like 7" Q7Z402 16 18983934-19063942 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.3;testis: 9.0;urinary bladder: 7.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 76.4;Early spermatids: 233.5;Late primary spermatocytes: 128.0;Late spermatids: 65.4;Oligodendrocytes: 135.6;Papillary tip epithelial cells: 92.1;Prostatic hillock cells: 156.6;Urothelial cells: 236.7" "Cell type enhanced" "Detected in all" "oligodendrocyte: 175.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Minor Salivary Gland - Endothelial cells, Skin - Outer root sheath cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029465 Uncertain Approved Vesicles NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 69: Urothelial cells - Basic cellular functions" Vesicles "HPA029465: " "unprognostic (3.76e-2)" "potential prognostic unfavorable (9.52e-6)" "unprognostic (5.03e-2)" "unprognostic (1.21e-1)" "unprognostic (2.97e-1)" "unprognostic (2.43e-1)" "unprognostic (4.13e-2)" "unprognostic (4.13e-2)" "unprognostic (2.97e-2)" "unprognostic (1.29e-3)" "unprognostic (3.79e-3)" "unprognostic (5.94e-3)" "unprognostic (4.72e-2)" "unprognostic (5.19e-2)" "unprognostic (4.62e-2)" "potential prognostic unfavorable (8.44e-6)" "unprognostic (2.03e-1)" "potential prognostic unfavorable (3.90e-4)" "unprognostic (1.09e-2)" "unprognostic (3.29e-1)" "unprognostic (2.04e-1)" "unprognostic (2.68e-1)" "unprognostic (1.94e-1)" "unprognostic (3.99e-1)" "unprognostic (1.77e-1)" "unprognostic (9.08e-2)" TMC8 "EVER2, EVIN2" ENSG00000167895 "Transmembrane channel like 8" Q8IU68 17 78130770-78142968 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 69.9;intestine: 48.4;lymphoid tissue: 108.3" "Cell type enhanced" "Detected in many" "B-cells: 139.9;Hematopoietic stem cells: 81.0;Hofbauer cells: 86.6;Innate lymphoid cells: 86.0;Kupffer cells: 67.6;Mast cells: 72.3;Megakaryocyte progenitors: 58.4;Megakaryocyte-Erythroid progenitors: 67.5;Microglia: 82.2;Neutrophil progenitors: 102.7;NK-cells: 172.9;T-cells: 160.6;Thymocytes: 68.6" "Group enriched" "Detected in some" 32 "central nervous system macrophage: 106.2;leukocyte: 229.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 9 "Leukemia: 53.0;lymphoma: 27.5;Myeloma: 52.8" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Minor Salivary Gland - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Skeletal muscle - Macrophages, Spleen - B-cells (Spleen), Stomach - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA047387, HPA054429" Uncertain Uncertain "Golgi apparatus" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 1 "Golgi apparatus" "HPA047387: , HPA054429: " "unprognostic (5.33e-2)" "unprognostic (7.08e-3)" "unprognostic (5.36e-2)" "potential prognostic favorable (2.06e-6)" "unprognostic (2.51e-2)" "unprognostic (4.20e-2)" "unprognostic (1.23e-1)" "unprognostic (5.34e-2)" "potential prognostic favorable (8.07e-5)" "unprognostic (2.32e-1)" "unprognostic (9.14e-3)" "unprognostic (9.02e-2)" "unprognostic (4.35e-2)" "unprognostic (2.14e-2)" "unprognostic (9.66e-3)" "unprognostic (6.79e-2)" "unprognostic (9.45e-2)" "unprognostic (3.12e-1)" "unprognostic (5.68e-2)" "unprognostic (2.62e-1)" "unprognostic (1.37e-2)" "unprognostic (3.52e-2)" "unprognostic (6.77e-3)" "unprognostic (3.59e-1)" "unprognostic (1.56e-1)" "unprognostic (3.79e-2)" "unprognostic (2.46e-1)" "unprognostic (8.51e-2)" "unprognostic (6.85e-2)" "unprognostic (1.62e-1)" "unprognostic (7.27e-2)" TMCC1 KIAA0779 ENSG00000172765 "Transmembrane and coiled-coil domain family 1" O94876 3 129647792-129893711 "Predicted intracellular proteins, Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Myonuclei: 779.6;Neutrophils: 1257.0" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 4 "Kidney Renal Clear Cell Carcinoma (TCGA): 102.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "neutrophil: 11.2" "Lineage enriched" "Detected in many" 5 "granulocytes: 11.2" "Cancer enhanced" "Detected in all" "Kidney cancer: 65.9" "Adrenal gland - Adrenal cortex cells, Spleen - Endothelial cells, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053894 Uncertain NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 15: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 24: Neutrophils - Innate immunity signal integration" 2 "HPA053894: " "unprognostic (5.47e-2)" "unprognostic (2.45e-2)" "unprognostic (1.07e-3)" "unprognostic (8.34e-3)" "unprognostic (4.43e-2)" "unprognostic (9.44e-3)" "unprognostic (8.02e-2)" "unprognostic (3.47e-3)" "unprognostic (1.65e-1)" "unprognostic (8.08e-3)" "potential prognostic favorable (1.81e-5)" "unprognostic (3.43e-3)" "unprognostic (2.49e-2)" "potential prognostic unfavorable (4.08e-4)" "unprognostic (4.58e-3)" "unprognostic (5.11e-2)" "unprognostic (1.77e-1)" "unprognostic (3.63e-2)" "unprognostic (4.93e-3)" "unprognostic (4.51e-2)" "potential prognostic unfavorable (3.71e-5)" "potential prognostic unfavorable (7.23e-4)" "unprognostic (4.58e-2)" "unprognostic (2.22e-1)" "unprognostic (3.25e-1)" "unprognostic (8.56e-2)" "unprognostic (1.61e-1)" "unprognostic (8.34e-2)" "unprognostic (1.73e-1)" "unprognostic (3.01e-2)" "unprognostic (1.22e-1)" TMCC2 "FLJ38497, HUCEP11" ENSG00000133069 "Transmembrane and coiled-coil domain family 2" O75069 1 205227946-205285632 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 83.1;brain: 29.0" "Cell type enhanced" "Detected in many" "Erythrocytes: 283.7;Oligodendrocytes: 86.1;Platelets: 89.1;Retinal horizontal cells: 66.1;Retinal pigment epithelial cells: 63.9;Rod photoreceptor cells: 36.2" "Cell type enhanced" "Detected in all" "oligodendrocyte: 115.1" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 11.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Liver - Erythroid cells, Minor Salivary Gland - Endothelial cells, Prostate - Fibroblasts, Skeletal muscle - Skeletal myocytes, Skin - Outer root sheath cells, Spleen - Erythrocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014254 Approved NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 45: Non-specific - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 6 "HPA014254: " "unprognostic (1.26e-1)" "unprognostic (1.01e-1)" "unprognostic (5.19e-3)" "unprognostic (1.66e-1)" "unprognostic (4.38e-3)" "unprognostic (2.39e-1)" "unprognostic (2.73e-1)" "unprognostic (3.30e-2)" "unprognostic (1.48e-1)" "unprognostic (2.47e-1)" "unprognostic (1.43e-1)" "unprognostic (2.37e-2)" "unprognostic (2.71e-1)" "unprognostic (1.83e-2)" TMCC3 KIAA1145 ENSG00000057704 "Transmembrane and coiled-coil domain family 3" Q9ULS5 12 94567122-94650557 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Colonocytes: 253.4;Enterocytes: 421.1;Epididymal basal cells: 415.2;Neutrophils: 1848.4;Ocular epithelial cells: 625.4;Podocytes: 237.7" "Group enriched" "Detected in many" 4 "central nervous system macrophage: 246.4;committed oligodendrocyte precursor: 119.7;endothelial cell: 255.3;midbrain-derived inhibitory: 120.0;oligodendrocyte: 151.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 47.0;neutrophil: 70.1" "Lineage enriched" "Detected in all" 9 "granulocytes: 70.1" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014272 Approved Approved "Endoplasmic reticulum,Vesicles" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 55: Lymphoma - Immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 7 "Endoplasmic reticulum" Vesicles "HPA014272: " "unprognostic (3.32e-1)" "unprognostic (6.74e-2)" "unprognostic (2.39e-2)" "unprognostic (1.99e-1)" "unprognostic (7.74e-2)" "unprognostic (1.31e-1)" "unprognostic (7.49e-2)" "unprognostic (1.13e-1)" "unprognostic (1.08e-1)" "unprognostic (1.27e-1)" "potential prognostic favorable (2.90e-10)" "unprognostic (1.15e-3)" "unprognostic (7.46e-2)" "unprognostic (6.13e-2)" "unprognostic (2.93e-2)" "unprognostic (6.24e-2)" "unprognostic (3.89e-2)" "unprognostic (1.06e-1)" "unprognostic (5.85e-2)" "unprognostic (1.28e-2)" "unprognostic (2.51e-2)" "unprognostic (8.86e-2)" "unprognostic (1.89e-2)" "unprognostic (2.15e-1)" "potential prognostic favorable (5.17e-4)" "unprognostic (2.29e-1)" "unprognostic (1.59e-1)" "unprognostic (8.66e-2)" "unprognostic (9.71e-2)" "unprognostic (1.00e-1)" "unprognostic (9.16e-2)" TMCO1 "HP10122, TMCC4" ENSG00000143183 "Transmembrane and coiled-coil domains 1" Q9UM00 1 165724293-165827755 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Disease variant, Glaucoma, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054768, HPA078775" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 21: Non-specific - Metabolism" "Cluster 45: Non-specific - Nuclear processes" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 15 "Endoplasmic reticulum" "HPA054768: , HPA078775: " "unprognostic (2.09e-1)" "unprognostic (9.30e-3)" "unprognostic (8.04e-2)" "unprognostic (1.23e-3)" "unprognostic (3.13e-1)" "unprognostic (3.73e-2)" "unprognostic (1.26e-1)" "unprognostic (8.83e-2)" "potential prognostic unfavorable (7.00e-5)" "unprognostic (2.09e-2)" "potential prognostic favorable (2.84e-5)" "unprognostic (7.88e-2)" "unprognostic (4.46e-3)" "unprognostic (3.80e-3)" "unprognostic (4.46e-2)" "unprognostic (5.08e-2)" "unprognostic (2.58e-2)" "unprognostic (1.02e-2)" "unprognostic (8.05e-2)" "unprognostic (4.12e-2)" "unprognostic (4.10e-1)" "unprognostic (7.53e-2)" "unprognostic (1.24e-1)" "unprognostic (1.54e-1)" "unprognostic (8.73e-2)" "unprognostic (3.06e-2)" "unprognostic (1.17e-1)" "unprognostic (1.84e-1)" "unprognostic (4.66e-2)" "unprognostic (4.06e-2)" "unprognostic (8.30e-2)" TMCO2 dJ39G22.2 ENSG00000188800 "Transmembrane and coiled-coil domains 2" Q7Z6W1 1 40245947-40251684 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 912 "testis: 123.7" "Group enriched" "Detected in some" 215 "Early spermatids: 3034.7;Late primary spermatocytes: 959.8;Late spermatids: 1496.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 3 TMCO3 "C13orf11, FLJ20623" ENSG00000150403 "Transmembrane and coiled-coil domains 3" Q6UWJ1 13 113491021-113554590 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 309.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 20.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039561, HPA048126" Uncertain Approved Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 15: Bone marrow - Innate immune response" "Cluster 25: Non-specific - Transcription" "Cluster 19: Non-specific - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" 1 Cytosol "HPA039561: , HPA048126: " "unprognostic (1.79e-1)" "unprognostic (5.77e-2)" "unprognostic (4.62e-1)" "unprognostic (1.88e-2)" "unprognostic (1.31e-1)" "unprognostic (5.37e-2)" "unprognostic (3.32e-1)" "unprognostic (1.55e-1)" "unprognostic (7.97e-2)" "unprognostic (1.76e-2)" "potential prognostic favorable (1.09e-5)" "unprognostic (5.89e-2)" "unprognostic (5.94e-2)" "validated prognostic unfavorable (1.70e-4)" "validated prognostic unfavorable (9.26e-4)" "unprognostic (5.95e-2)" "unprognostic (1.29e-3)" "unprognostic (5.04e-3)" "unprognostic (2.08e-1)" "unprognostic (1.85e-2)" "unprognostic (2.39e-1)" "unprognostic (2.62e-1)" "unprognostic (1.26e-1)" "unprognostic (7.35e-2)" "unprognostic (1.49e-1)" "unprognostic (3.49e-2)" "unprognostic (3.77e-1)" "unprognostic (6.44e-2)" "unprognostic (1.08e-1)" "unprognostic (8.49e-3)" "unprognostic (3.76e-1)" TMCO4 DKFZp686C23231 ENSG00000162542 "Transmembrane and coiled-coil domains 4" Q5TGY1 1 19682240-19799945 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Renal collecting duct intercalated cells: 234.3" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 94.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA014601, HPA014620" Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 3: Choroid plexus - Cilium" "Cluster 37: Non-specific - mRNA processing" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 2 "Endoplasmic reticulum" "HPA014601: , HPA014620: " "unprognostic (4.68e-1)" "unprognostic (4.50e-1)" "unprognostic (2.47e-1)" "unprognostic (7.32e-2)" "unprognostic (3.45e-1)" "unprognostic (4.52e-2)" "unprognostic (1.55e-2)" "potential prognostic unfavorable (7.50e-5)" "unprognostic (1.09e-1)" "potential prognostic unfavorable (3.15e-4)" "potential prognostic favorable (2.22e-8)" "unprognostic (2.61e-2)" "potential prognostic favorable (5.56e-5)" "unprognostic (1.96e-3)" "unprognostic (1.26e-1)" "unprognostic (4.83e-2)" "unprognostic (5.20e-2)" "unprognostic (3.65e-2)" "unprognostic (1.33e-1)" "unprognostic (1.11e-1)" "unprognostic (1.28e-1)" "unprognostic (1.64e-2)" "unprognostic (8.32e-2)" "unprognostic (2.39e-1)" "unprognostic (1.54e-1)" "unprognostic (2.93e-2)" "unprognostic (1.79e-2)" "unprognostic (9.52e-2)" "unprognostic (8.26e-2)" "unprognostic (5.66e-2)" "unprognostic (7.40e-2)" TMCO5A "MGC35118, TMCO5" ENSG00000166069 "Transmembrane and coiled-coil domains 5A" Q8N6Q1 15 37921939-37967724 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 178 "testis: 113.4" "Cell type enriched" "Detected in some" 4 "Late spermatids: 6178.1" "Cell type enhanced" "Detected in single" "oligodendrocyte: 1.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA056530, HPA064017" Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 18: Non-specific - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 5 "Plasma membrane, Cytosol" "HPA056530: , HPA064017: " TMCO6 "FLJ39769, PRO1580" ENSG00000113119 "Transmembrane and coiled-coil domains 6" Q96DC7 5 140639435-140645408 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 27.3;Differentiating spermatogonia: 21.4;Early primary spermatocytes: 21.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037473, HPA037474" Uncertain Approved Nucleoplasm,Mitochondria No No "Cluster 35: Neutrophils - Protein binding" "Cluster 76: Non-specific - Metabolism" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 18: Adrenal cortex cells - Steroidogensis" 7 Mitochondria Nucleoplasm "HPA037473: , HPA037474: " "unprognostic (6.18e-2)" "unprognostic (7.68e-2)" "unprognostic (2.79e-1)" "unprognostic (1.08e-1)" "unprognostic (1.32e-1)" "unprognostic (4.98e-2)" "potential prognostic unfavorable (5.63e-4)" "unprognostic (2.78e-1)" "unprognostic (1.70e-1)" "unprognostic (2.22e-1)" "unprognostic (3.77e-3)" "unprognostic (3.09e-2)" "unprognostic (2.05e-1)" "unprognostic (5.60e-2)" "unprognostic (1.48e-1)" "unprognostic (1.04e-1)" "unprognostic (9.07e-2)" "unprognostic (1.71e-1)" "unprognostic (2.37e-1)" "unprognostic (2.07e-2)" "unprognostic (9.12e-2)" "unprognostic (1.21e-1)" "unprognostic (4.83e-2)" "unprognostic (6.66e-2)" "unprognostic (8.55e-2)" "unprognostic (3.86e-2)" "unprognostic (7.00e-3)" "unprognostic (4.18e-2)" "unprognostic (1.59e-1)" "unprognostic (8.11e-2)" "unprognostic (7.01e-2)" TMDD1 "C12orf81, hCG1648055" ENSG00000284730 "Transmembrane and death domain 1" P0DPE3 12 51813921-51814925 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 4 "liver: 1.4;testis: 3.9" "Cell type enhanced" "Detected in some" "Breast lactating cells: 6.8;Early spermatids: 32.8;Epididymal principal cells: 13.3;Hepatocytes: 4.5;Late primary spermatocytes: 19.1;Late spermatids: 13.4" "Cell type enhanced" "Detected in single" "fibroblast: 2.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 3: Rhabdoid - Membrane components" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" "unprognostic (4.42e-2)" TMED1 "Il1rl1l, IL1RL1LG, MGC1270, p24g1, p24gamma1, ST2L" ENSG00000099203 "Transmembrane p24 trafficking protein 1" Q13445 19 10832067-10836318 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Immunity, Innate immunity, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 132.9;Extravillous trophoblasts: 125.7;Migrating cytotrophoblasts: 115.5;Syncytiotrophoblasts: 174.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018507 Uncertain NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 23: Non-specific - Transcription" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 33 "HPA018507: " "unprognostic (7.02e-2)" "unprognostic (2.69e-1)" "unprognostic (9.67e-2)" "unprognostic (2.67e-1)" "unprognostic (5.59e-2)" "unprognostic (2.60e-1)" "unprognostic (6.47e-2)" "unprognostic (3.10e-1)" "unprognostic (2.10e-1)" "unprognostic (5.88e-3)" "potential prognostic favorable (3.09e-6)" "unprognostic (1.28e-1)" "potential prognostic favorable (1.57e-4)" "unprognostic (2.61e-3)" "unprognostic (1.53e-3)" "unprognostic (2.59e-3)" "unprognostic (5.30e-2)" "unprognostic (9.74e-2)" "unprognostic (2.39e-1)" "unprognostic (2.30e-1)" "unprognostic (1.52e-1)" "unprognostic (3.77e-1)" "unprognostic (4.69e-2)" "unprognostic (8.71e-2)" "unprognostic (8.32e-3)" "unprognostic (1.10e-1)" "unprognostic (5.27e-2)" "unprognostic (8.77e-2)" "unprognostic (9.87e-2)" "unprognostic (1.87e-1)" "unprognostic (3.57e-1)" TMED10 "p23, P24(DELTA), p24d1, p24delta1, TMP21" ENSG00000170348 "Transmembrane p24 trafficking protein 10" P49755 14 75131469-75176612 "Essential proteins, Predicted membrane proteins, Transporters" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epididymal principal cells: 690.7;Esophageal apical cells: 950.0;Extravillous trophoblasts: 882.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034442, CAB037251, HPA047139, HPA050539" Enhanced Supported "Golgi apparatus" NA NA 130000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 8: Non-specific - Secretory pathway" 171 "Golgi apparatus" "CAB034442: , CAB037251: , HPA047139: , HPA050539: " "unprognostic (1.84e-1)" "unprognostic (4.93e-2)" "unprognostic (5.60e-2)" "unprognostic (5.02e-3)" "unprognostic (9.01e-2)" "unprognostic (1.25e-1)" "unprognostic (1.90e-1)" "unprognostic (8.64e-3)" "unprognostic (8.91e-3)" "unprognostic (6.57e-2)" "potential prognostic favorable (1.82e-6)" "unprognostic (7.45e-2)" "unprognostic (9.80e-2)" "unprognostic (8.86e-3)" "unprognostic (8.86e-2)" "unprognostic (1.39e-2)" "unprognostic (6.33e-2)" "unprognostic (8.47e-2)" "unprognostic (3.31e-2)" "unprognostic (1.12e-1)" "unprognostic (2.14e-2)" "unprognostic (1.87e-2)" "unprognostic (1.17e-1)" "unprognostic (1.22e-1)" "unprognostic (1.38e-1)" "unprognostic (2.44e-2)" "unprognostic (1.42e-1)" "unprognostic (4.78e-2)" "unprognostic (2.98e-1)" "potential prognostic unfavorable (3.96e-4)" "unprognostic (1.26e-1)" TMED2 "P24A, p24b1, p24beta1, RNP24" ENSG00000086598 "Transmembrane p24 trafficking protein 2" Q15363 12 123584533-123598582 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 653.7;Esophageal apical cells: 669.4;Extravillous trophoblasts: 917.5;Gastric chief cells: 670.5;Hepatocytes: 621.2;Parietal cells: 572.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014060 Approved Supported Vesicles NA NA 58000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 38: Non-specific - Transcription" "Cluster 8: Non-specific - Secretory pathway" 95 Vesicles "HPA014060: " "unprognostic (2.56e-1)" "unprognostic (1.28e-2)" "unprognostic (8.14e-2)" "potential prognostic unfavorable (3.36e-5)" "unprognostic (3.00e-3)" "unprognostic (2.87e-2)" "unprognostic (1.55e-2)" "unprognostic (3.87e-2)" "potential prognostic unfavorable (1.20e-4)" "unprognostic (7.38e-3)" "unprognostic (2.18e-3)" "unprognostic (8.68e-2)" "unprognostic (1.90e-2)" "unprognostic (1.03e-3)" "potential prognostic unfavorable (9.36e-4)" "unprognostic (8.83e-3)" "unprognostic (1.50e-2)" "unprognostic (1.09e-1)" "unprognostic (2.05e-1)" "unprognostic (5.87e-2)" "unprognostic (5.61e-2)" "unprognostic (6.51e-3)" "unprognostic (7.65e-2)" "unprognostic (4.16e-2)" "unprognostic (2.56e-2)" "unprognostic (1.10e-1)" "unprognostic (4.26e-2)" "unprognostic (2.58e-1)" "unprognostic (1.62e-1)" "unprognostic (2.24e-2)" "unprognostic (8.78e-2)" TMED3 "C15orf22, p24B, p24g4, p24gamma4" ENSG00000166557 "Transmembrane p24 trafficking protein 3" Q9Y3Q3 15 79311112-79427432 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 386.0" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 381.5;Esophageal apical cells: 1057.7;Esophageal suprabasal cells: 467.7;Extravillous trophoblasts: 413.7;Lacrimal acinar cells: 448.4;Salivary acinar cells: 684.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049314, HPA076949" Enhanced Supported "Golgi apparatus" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 82: Salivary gland - Secretion" "Cluster 44: Non-specific - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 13 "Golgi apparatus" "HPA049314: , HPA076949: " "unprognostic (4.09e-1)" "potential prognostic unfavorable (6.22e-5)" "unprognostic (1.35e-1)" "unprognostic (7.39e-3)" "unprognostic (1.77e-2)" "unprognostic (1.08e-1)" "unprognostic (6.84e-2)" "unprognostic (5.18e-2)" "unprognostic (1.19e-1)" "unprognostic (8.87e-2)" "unprognostic (6.41e-2)" "potential prognostic unfavorable (5.18e-6)" "unprognostic (6.73e-3)" "unprognostic (2.64e-2)" "unprognostic (7.46e-2)" "unprognostic (2.69e-2)" "unprognostic (1.89e-1)" "unprognostic (1.05e-1)" "unprognostic (1.85e-1)" "unprognostic (1.47e-1)" "unprognostic (3.13e-1)" "unprognostic (1.05e-1)" "unprognostic (5.99e-2)" "unprognostic (4.37e-1)" "unprognostic (5.76e-2)" "unprognostic (1.76e-1)" "unprognostic (3.87e-1)" "unprognostic (1.31e-1)" "unprognostic (2.82e-1)" "unprognostic (5.54e-2)" "unprognostic (3.18e-2)" TMED4 "HNLF, p24a3, p24alpha3" ENSG00000158604 "Transmembrane p24 trafficking protein 4" Q7Z7H5 7 44577894-44582287 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014650 Approved "Intracellular and membrane" Transport NA NA 43000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 55: Non-specific - Transcription" "Cluster 67: Non-specific - Unknown function" "Cluster 78: Plasma cells - Antibody production & ER-stress response" 15 "HPA014650: " "unprognostic (1.34e-2)" "unprognostic (1.54e-2)" "unprognostic (3.50e-1)" "unprognostic (2.30e-2)" "unprognostic (7.68e-2)" "unprognostic (4.00e-2)" "unprognostic (2.40e-3)" "unprognostic (1.59e-3)" "unprognostic (9.46e-3)" "unprognostic (2.11e-1)" "potential prognostic favorable (5.58e-7)" "unprognostic (1.40e-1)" "unprognostic (5.10e-2)" "unprognostic (1.21e-3)" "unprognostic (1.55e-2)" "unprognostic (1.39e-3)" "unprognostic (1.97e-1)" "unprognostic (3.89e-1)" "unprognostic (3.52e-2)" "unprognostic (1.81e-1)" "unprognostic (1.55e-1)" "unprognostic (3.84e-3)" "unprognostic (4.65e-2)" "unprognostic (1.49e-1)" "unprognostic (2.13e-1)" "unprognostic (4.10e-1)" "unprognostic (7.44e-2)" "unprognostic (1.10e-1)" "unprognostic (1.59e-1)" "unprognostic (3.27e-1)" "unprognostic (5.76e-2)" TMED5 "CGI-100, p24g2, p24gamma2" ENSG00000117500 "Transmembrane p24 trafficking protein 5" Q9Y3A6 1 93149742-93180516 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 260.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Macrophages, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050289 Approved NA NA 20000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 37: Non-specific - mRNA processing" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 45 "HPA050289: " "unprognostic (4.26e-2)" "unprognostic (1.32e-1)" "unprognostic (2.12e-2)" "unprognostic (2.38e-3)" "unprognostic (2.15e-2)" "unprognostic (3.86e-1)" "unprognostic (4.48e-2)" "unprognostic (1.63e-2)" "unprognostic (2.02e-1)" "unprognostic (1.38e-2)" "potential prognostic favorable (2.85e-7)" "unprognostic (7.47e-3)" "unprognostic (1.16e-1)" "unprognostic (1.15e-1)" "unprognostic (4.43e-2)" "unprognostic (3.62e-2)" "unprognostic (6.14e-2)" "unprognostic (1.25e-2)" "unprognostic (2.14e-2)" "unprognostic (8.60e-2)" "unprognostic (9.42e-3)" "unprognostic (1.60e-2)" "unprognostic (3.20e-3)" "unprognostic (1.50e-1)" "unprognostic (6.16e-3)" "unprognostic (4.70e-2)" "unprognostic (1.70e-1)" "unprognostic (6.32e-2)" "unprognostic (5.51e-2)" "unprognostic (4.17e-1)" "unprognostic (1.55e-1)" TMED6 "MGC23911, p24g5, p24gamma5" ENSG00000157315 "Transmembrane p24 trafficking protein 6" Q8WW62 16 69343250-69351786 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "pancreas: 281.9" "Group enriched" "Detected in some" 16 "Gastric chief cells: 237.0;Parietal cells: 90.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Stomach - Chief cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA012532 Approved NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 34: Non-specific - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 97: Non-specific - Cellular respiration" "HPA012532: " "unprognostic (1.17e-1)" "unprognostic (1.27e-2)" "unprognostic (5.01e-2)" "unprognostic (6.56e-2)" "unprognostic (6.29e-3)" "unprognostic (2.55e-1)" "validated prognostic favorable (8.72e-8)" "validated prognostic favorable (1.05e-6)" "unprognostic (2.68e-1)" "unprognostic (1.62e-1)" "unprognostic (2.63e-2)" "unprognostic (7.76e-2)" "unprognostic (2.05e-1)" "unprognostic (1.60e-1)" "unprognostic (2.17e-2)" "unprognostic (9.89e-2)" "unprognostic (1.24e-1)" "unprognostic (2.60e-1)" "unprognostic (2.44e-2)" "unprognostic (2.78e-1)" "unprognostic (2.34e-2)" TMED7 "CGI-109, FLJ90481, p24g3, p24gamma3" ENSG00000134970 "Transmembrane p24 trafficking protein 7" Q9Y3B3 5 115613210-115632992 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Astrocytes: 24.1;Bergmann glia: 23.4;Brain excitatory neurons: 22.5;Brain inhibitory neurons: 24.5;Choroid plexus epithelial cells: 24.1;Ependymal cells: 38.3;Microglia: 32.9;Oligodendrocyte progenitor cells: 41.9;Oligodendrocytes: 62.3;Other brain neurons: 30.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008960, CAB025883" Supported NA NA 49000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 98: Neurons - Neurotransmission & signaling" 31 "CAB025883: , HPA008960: " "unprognostic (8.81e-2)" "unprognostic (4.34e-2)" "unprognostic (4.63e-1)" "unprognostic (1.13e-2)" "unprognostic (2.31e-2)" "unprognostic (4.92e-3)" "unprognostic (1.02e-1)" "potential prognostic unfavorable (8.30e-5)" "unprognostic (2.99e-2)" "unprognostic (3.97e-2)" "potential prognostic favorable (7.00e-7)" "unprognostic (2.51e-2)" "unprognostic (1.31e-1)" "unprognostic (6.61e-2)" "unprognostic (1.98e-1)" "unprognostic (5.97e-3)" "unprognostic (2.87e-2)" "unprognostic (2.82e-2)" "unprognostic (2.80e-2)" "unprognostic (8.10e-3)" "potential prognostic unfavorable (2.64e-4)" "unprognostic (5.51e-3)" "unprognostic (3.26e-3)" "unprognostic (1.59e-1)" "unprognostic (1.85e-1)" "potential prognostic unfavorable (8.21e-6)" "unprognostic (1.91e-1)" "unprognostic (5.58e-2)" "unprognostic (3.50e-1)" "unprognostic (2.73e-2)" "unprognostic (1.63e-1)" TMED7-TICAM2 ENSG00000251201 "TMED7-TICAM2 readthrough" 5 115578642-115626161 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 31.9;Cardiomyocytes: 53.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" HPA008960 Uncertain NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 30: White matter - Myelination" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" "HPA008960: " "unprognostic (6.15e-3)" "potential prognostic unfavorable (6.58e-4)" "unprognostic (3.72e-3)" "unprognostic (2.71e-1)" "unprognostic (2.79e-2)" "unprognostic (3.08e-2)" "unprognostic (1.87e-3)" "unprognostic (1.04e-1)" "potential prognostic favorable (4.97e-5)" "unprognostic (1.39e-1)" "unprognostic (2.99e-3)" "potential prognostic unfavorable (2.06e-4)" "unprognostic (6.70e-3)" "unprognostic (5.23e-3)" "unprognostic (9.53e-3)" "potential prognostic unfavorable (8.51e-5)" "potential prognostic unfavorable (7.80e-4)" "unprognostic (3.54e-3)" "unprognostic (1.26e-1)" "unprognostic (1.28e-1)" "unprognostic (8.37e-2)" "unprognostic (5.81e-3)" "unprognostic (2.51e-1)" "unprognostic (2.23e-1)" "unprognostic (5.41e-2)" "unprognostic (1.30e-1)" "unprognostic (2.25e-3)" TMED8 FAM15B ENSG00000100580 "Transmembrane p24 trafficking protein family member 8" Q6PL24 14 77335029-77377094 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 169.7;Neutrophils: 230.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001205 Approved Approved "Vesicles,Plasma membrane" NA NA 35000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 32 "Plasma membrane" Vesicles "HPA001205: " "unprognostic (1.64e-1)" "unprognostic (2.38e-1)" "unprognostic (1.68e-1)" "unprognostic (3.60e-1)" "unprognostic (7.74e-2)" "unprognostic (1.27e-1)" "unprognostic (8.81e-2)" "unprognostic (1.80e-3)" "unprognostic (1.93e-1)" "potential prognostic unfavorable (5.74e-4)" "potential prognostic favorable (4.12e-7)" "unprognostic (1.20e-3)" "unprognostic (1.67e-2)" "unprognostic (2.33e-3)" "unprognostic (6.60e-2)" "unprognostic (2.41e-1)" "unprognostic (1.30e-1)" "unprognostic (1.13e-1)" "unprognostic (3.76e-3)" "unprognostic (1.84e-1)" "unprognostic (7.44e-3)" "unprognostic (7.10e-2)" "unprognostic (1.18e-1)" "unprognostic (3.08e-1)" "unprognostic (8.96e-2)" "unprognostic (3.29e-1)" "unprognostic (1.80e-1)" "unprognostic (9.67e-3)" "unprognostic (2.64e-1)" "unprognostic (3.02e-2)" "unprognostic (2.13e-1)" TMED9 "HSGP25L2G, p24a2, p24alpha2" ENSG00000184840 "Transmembrane p24 trafficking protein 9" Q9BVK6 5 177592203-177597242 "Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 608.7;Epididymal principal cells: 502.8;Esophageal apical cells: 624.7;Esophageal suprabasal cells: 469.1;Extravillous trophoblasts: 1277.9;Migrating cytotrophoblasts: 637.3;Syncytiotrophoblasts: 1001.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014650 Approved NA NA 49000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 70: Non-specific - Protein processing" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 63: Non-specific - Protein processing" "Cluster 8: Non-specific - Secretory pathway" 43 "HPA014650: " "unprognostic (4.10e-3)" "unprognostic (1.14e-3)" "unprognostic (4.88e-2)" "unprognostic (1.66e-3)" "unprognostic (2.54e-1)" "unprognostic (2.90e-1)" "unprognostic (1.65e-3)" "unprognostic (1.29e-3)" "potential prognostic unfavorable (7.32e-4)" "unprognostic (1.02e-2)" "unprognostic (5.49e-3)" "potential prognostic unfavorable (3.30e-4)" "unprognostic (6.79e-2)" "unprognostic (3.45e-3)" "potential prognostic unfavorable (9.89e-4)" "unprognostic (4.99e-3)" "unprognostic (4.46e-2)" "unprognostic (1.03e-2)" "unprognostic (1.96e-1)" "unprognostic (9.44e-2)" "unprognostic (1.55e-2)" "unprognostic (1.29e-1)" "unprognostic (1.40e-1)" "unprognostic (2.84e-1)" "unprognostic (2.80e-1)" "unprognostic (3.27e-2)" "unprognostic (1.32e-1)" "unprognostic (1.04e-1)" "unprognostic (5.16e-2)" "unprognostic (6.91e-3)" "unprognostic (3.92e-1)" TMEFF1 "C9orf2, CT120.1, H7365" ENSG00000241697 "Transmembrane protein with EGF like and two follistatin like domains 1" Q8IYR6 9 100473149-100577636 "Predicted membrane proteins, Transporters" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "brain: 12.9;testis: 3.8" "Cell type enhanced" "Detected in some" "Astrocytes: 26.8;Brain excitatory neurons: 71.0;Brain inhibitory neurons: 105.6;Ependymal cells: 25.0;Oligodendrocyte progenitor cells: 51.7;Oligodendrocytes: 308.7;Other brain neurons: 89.1" "Cell type enhanced" "Detected in all" "oligodendrocyte: 441.6" "Group enriched" "Detected in some" 4 "Glioblastoma Multiforme (TCGA): 3.0;Ovary Serous Cystadenocarcinoma (TCGA): 4.6;Testicular Germ Cell Tumor (TCGA): 2.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 28.7" "Colon - Enteric glia cells, Liver - Vascular endothelial cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051501 Uncertain NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 80: Oligodendrocytes - Myelination" 3 "HPA051501: " "unprognostic (4.01e-2)" "unprognostic (9.88e-2)" "potential prognostic favorable (5.27e-5)" "unprognostic (6.44e-2)" "unprognostic (2.00e-1)" "unprognostic (2.40e-1)" "unprognostic (2.94e-3)" "unprognostic (5.58e-1)" TMEFF2 "CT120.2, HPP1, TENB2, TPEF, TR" ENSG00000144339 "Transmembrane protein with EGF like and two follistatin like domains 2" Q9UIK5 2 191949043-192194933 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 23.3;prostate: 34.3;seminal vesicle: 12.5" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 418.7;Brain inhibitory neurons: 420.4;Cardiomyocytes: 1038.7;Epicardial cells: 1669.2;Mesothelial cells: 325.1;Oligodendrocyte progenitor cells: 247.5;Oligodendrocytes: 1438.5;Oocytes: 294.7;Other brain neurons: 335.7;Prostatic glandular cells: 655.7;Retinal horizontal cells: 376.6" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in some" 17 "Prostate Adenocarcinoma (TCGA): 192.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "Bone cancer: 17.2;prostate cancer: 27.6" "Adrenal gland - Adrenal medulla cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015587 Approved "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 65: Brain - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 109: Neurons - Neuronal signaling" 5 "HPA015587: " "unprognostic (8.51e-2)" "potential prognostic favorable (2.12e-4)" "unprognostic (2.23e-2)" "unprognostic (3.11e-1)" TMEM100 "FLJ10970, FLJ37856" ENSG00000166292 "Transmembrane protein 100" Q9NV29 17 55719627-55732121 "Predicted membrane proteins, Transporters" Differentiation "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 179.9" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 31.9;Epididymal basal cells: 20.4;Epididymal efferent duct absorptive cells: 46.6;Epididymal principal cells: 53.1;Fibroblasts: 41.4;Hepatocytes: 20.7;Leydig cells: 30.7;Lymphatic endothelial cells: 60.5;Oligodendrocyte progenitor cells: 32.3;Ovarian stromal cells: 25.5;Peritubular myoid cells: 50.2;Schwann cells: 32.6;Vascular endothelial cells: 54.1" "Cell type enhanced" "Detected in some" "committed oligodendrocyte precursor: 19.4;fibroblast: 20.5;oligodendrocyte precursor cell: 35.4" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 30.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "ovarian cancer: 49.8;Rhabdoid: 19.8" "Minor Salivary Gland - Fibroblasts, Prostate - Fibroblasts, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055936 Approved Uncertain Nucleoplasm NA NA "Cluster 13: Lung - Secretion" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 32 Nucleoplasm "HPA055936: " "unprognostic (3.92e-2)" "unprognostic (5.57e-2)" "unprognostic (1.15e-2)" "unprognostic (1.46e-2)" "unprognostic (1.60e-1)" "unprognostic (3.90e-3)" "potential prognostic favorable (1.68e-4)" "unprognostic (1.12e-1)" "unprognostic (1.23e-1)" "unprognostic (5.39e-2)" "unprognostic (1.56e-2)" "validated prognostic favorable (5.05e-4)" "validated prognostic favorable (6.83e-4)" "unprognostic (5.06e-3)" "unprognostic (1.10e-3)" "unprognostic (3.73e-2)" "unprognostic (3.67e-1)" "unprognostic (1.77e-1)" "unprognostic (4.08e-3)" "unprognostic (2.42e-2)" "unprognostic (7.79e-2)" "unprognostic (4.61e-3)" "unprognostic (1.99e-1)" "unprognostic (6.73e-3)" "unprognostic (8.32e-2)" "unprognostic (3.75e-2)" "unprognostic (2.14e-1)" TMEM101 "FLJ23987, MGC4251" ENSG00000091947 "Transmembrane protein 101" Q96IK0 17 44011188-44023946 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Distal convoluted tubule cells: 254.2;Endometrial glandular cells: 434.3;Endometrial luminal cells: 777.2;Renal collecting duct intercalated cells: 794.7" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 300.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells, Kidney - Intercalated cells, Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039739, HPA075651" Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 72: Kidney - Transmembrane transport" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 15 "Nucleoplasm, Plasma membrane" "HPA039739: , HPA075651: " "unprognostic (2.53e-1)" "unprognostic (5.16e-3)" "unprognostic (4.44e-1)" "unprognostic (2.50e-1)" "unprognostic (1.32e-1)" "unprognostic (2.97e-2)" "unprognostic (3.22e-2)" "unprognostic (6.82e-3)" "unprognostic (3.56e-3)" "unprognostic (2.76e-2)" "potential prognostic favorable (8.44e-5)" "unprognostic (1.17e-1)" "unprognostic (2.47e-1)" "validated prognostic unfavorable (3.40e-4)" "validated prognostic unfavorable (1.73e-5)" "unprognostic (1.30e-1)" "unprognostic (8.54e-3)" "unprognostic (1.17e-1)" "unprognostic (8.86e-2)" "unprognostic (4.98e-2)" "unprognostic (1.07e-2)" "unprognostic (3.30e-1)" "unprognostic (7.53e-2)" "unprognostic (1.74e-1)" "unprognostic (1.58e-2)" "unprognostic (2.93e-1)" "unprognostic (2.47e-1)" "unprognostic (1.27e-1)" "unprognostic (2.77e-1)" "unprognostic (3.28e-1)" "unprognostic (2.20e-1)" TMEM102 "CBAP, FLJ36878" ENSG00000181284 "Transmembrane protein 102" Q8N9M5 17 7435435-7437679 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Late spermatids: 1.5;Loop of henle epithelial cells: 1.7;Paneth cells: 3.9;Papillary tip epithelial cells: 3.3;Podocytes: 1.5;Proximal tubule cells: 1.2;Renal collecting duct principal cells: 2.4" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 1.4;endothelial cell: 1.3;leukocyte: 2.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "eosinophil: 3.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Spleen - Macrophages, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA024433 Uncertain Approved Vesicles NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 47: Endothelial cells - Vasculature" "Cluster 42: Non-specific - Unknown function" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 11 Vesicles "HPA024433: " "unprognostic (1.05e-1)" "unprognostic (1.48e-1)" "unprognostic (9.97e-2)" "potential prognostic unfavorable (6.11e-4)" "unprognostic (3.91e-2)" "unprognostic (3.15e-2)" "unprognostic (1.72e-2)" "unprognostic (8.25e-2)" "unprognostic (3.27e-1)" "unprognostic (2.28e-1)" "potential prognostic favorable (1.99e-4)" "unprognostic (1.28e-1)" "unprognostic (7.37e-3)" "unprognostic (2.33e-1)" "unprognostic (2.10e-2)" "unprognostic (1.02e-1)" "unprognostic (4.76e-2)" "unprognostic (9.62e-2)" "unprognostic (1.10e-1)" "unprognostic (1.20e-1)" "unprognostic (2.83e-1)" "unprognostic (3.56e-1)" "unprognostic (7.76e-2)" "unprognostic (1.13e-1)" "unprognostic (2.50e-2)" "unprognostic (1.49e-1)" "unprognostic (2.18e-2)" "unprognostic (6.09e-3)" "unprognostic (4.04e-2)" "unprognostic (1.76e-1)" "unprognostic (2.84e-2)" TMEM104 "FLJ00021, FLJ20255" ENSG00000109066 "Transmembrane protein 104" Q8NE00 17 74776499-74839753 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 48.9;Platelets: 64.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044330 Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 27: Breast cancer - Unknown function" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" Nucleoplasm "Golgi apparatus" "HPA044330: " "unprognostic (4.12e-1)" "unprognostic (7.51e-3)" "unprognostic (3.00e-2)" "unprognostic (3.03e-2)" "unprognostic (1.71e-1)" "unprognostic (5.69e-2)" "unprognostic (8.94e-2)" "unprognostic (7.53e-2)" "unprognostic (6.42e-2)" "unprognostic (3.64e-1)" "unprognostic (2.46e-2)" "unprognostic (1.13e-3)" "unprognostic (8.25e-2)" "validated prognostic unfavorable (4.89e-5)" "validated prognostic unfavorable (4.81e-4)" "unprognostic (4.33e-2)" "unprognostic (3.31e-1)" "unprognostic (8.01e-2)" "unprognostic (2.83e-2)" "unprognostic (2.01e-1)" "unprognostic (2.18e-2)" "potential prognostic favorable (2.80e-4)" "unprognostic (3.11e-3)" "unprognostic (2.88e-1)" "unprognostic (5.94e-1)" "unprognostic (1.36e-1)" "unprognostic (1.04e-1)" "unprognostic (2.08e-1)" "unprognostic (1.35e-1)" "unprognostic (9.72e-3)" "unprognostic (1.34e-1)" TMEM106A MGC20235 ENSG00000184988 "Transmembrane protein 106A" Q96A25 17 43211835-43220041 "Predicted membrane proteins, Transporters" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 20.4" "Cell type enhanced" "Detected in many" "cDC: 46.8;Hofbauer cells: 107.9;Kupffer cells: 61.5;Macrophages: 65.5;Microglia: 69.4;monocytes: 51.8;Proximal tubule cells: 94.5" "Cell type enriched" "Detected in all" 5 "central nervous system macrophage: 87.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 26.7" "Lineage enriched" "Detected in all" 4 "granulocytes: 26.7" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adrenal gland - Macrophages, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Spleen - Macrophages, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 72: Kidney - Transmembrane transport" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 117 "unprognostic (4.57e-2)" "unprognostic (2.20e-2)" "unprognostic (1.75e-1)" "unprognostic (5.11e-2)" "unprognostic (2.08e-3)" "unprognostic (1.49e-1)" "unprognostic (1.81e-2)" "unprognostic (7.98e-2)" "unprognostic (1.77e-2)" "unprognostic (4.21e-2)" "potential prognostic favorable (3.59e-4)" "unprognostic (1.86e-3)" "unprognostic (1.73e-2)" "unprognostic (4.91e-2)" "unprognostic (2.48e-1)" "unprognostic (8.13e-2)" "unprognostic (1.88e-3)" "unprognostic (2.60e-2)" "unprognostic (1.60e-2)" "unprognostic (1.52e-1)" "unprognostic (9.10e-2)" "unprognostic (3.08e-2)" "potential prognostic unfavorable (2.57e-4)" "unprognostic (1.17e-2)" "unprognostic (1.48e-3)" "unprognostic (2.80e-1)" "unprognostic (5.00e-2)" "unprognostic (1.50e-1)" "unprognostic (6.38e-2)" "unprognostic (3.66e-2)" "unprognostic (2.64e-1)" TMEM106B "FLJ11273, MGC33727" ENSG00000106460 "Transmembrane protein 106B" Q9NUM4 7 12211270-12243367 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Amyotrophic lateral sclerosis, Disease variant, Leukodystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058342 Approved Supported Endosomes,Lysosomes NA NA "Cluster 27: T-cells - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 67: Non-specific - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 29 "Endosomes, Lysosomes" "HPA058342: " "unprognostic (8.62e-2)" "unprognostic (8.24e-2)" "unprognostic (2.50e-2)" "unprognostic (9.59e-3)" "unprognostic (1.09e-2)" "unprognostic (7.99e-2)" "unprognostic (3.25e-1)" "unprognostic (6.69e-3)" "unprognostic (7.51e-2)" "unprognostic (1.11e-1)" "potential prognostic favorable (2.45e-7)" "unprognostic (3.09e-2)" "unprognostic (4.45e-2)" "unprognostic (1.21e-1)" "unprognostic (2.84e-2)" "potential prognostic unfavorable (5.12e-4)" "unprognostic (2.96e-1)" "unprognostic (1.13e-1)" "unprognostic (1.42e-1)" "unprognostic (2.83e-1)" "potential prognostic unfavorable (2.73e-4)" "unprognostic (1.14e-2)" "unprognostic (2.46e-2)" "unprognostic (1.12e-1)" "unprognostic (3.84e-2)" "unprognostic (6.50e-2)" "unprognostic (1.46e-1)" "unprognostic (6.07e-2)" "unprognostic (2.75e-1)" "unprognostic (4.30e-2)" "unprognostic (2.41e-1)" TMEM106C MGC5576 ENSG00000134291 "Transmembrane protein 106C" Q9BVX2 12 47963569-47968878 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 210.1;Enteric stem cells: 171.1;Enteric transient amplifying cells: 254.1;Enterocytes: 332.6;Epididymal clear cells: 347.0;Gastric progenitor cells: 166.6;Paneth cells: 208.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Stomach - Mitotic cells (Stomach), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047204 Enhanced NA Yes "Cluster 3: Non-specific - Nuclear processes" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 41 "HPA047204: " "unprognostic (8.13e-2)" "unprognostic (4.23e-3)" "unprognostic (1.76e-1)" "unprognostic (1.28e-1)" "unprognostic (7.60e-2)" "unprognostic (1.52e-1)" "unprognostic (1.84e-1)" "unprognostic (4.03e-1)" "unprognostic (1.25e-1)" "unprognostic (8.47e-2)" "potential prognostic favorable (1.34e-6)" "unprognostic (1.25e-1)" "unprognostic (1.96e-1)" "validated prognostic unfavorable (2.86e-7)" "validated prognostic unfavorable (5.94e-6)" "unprognostic (1.82e-2)" "unprognostic (3.19e-3)" "unprognostic (7.97e-2)" "unprognostic (3.66e-2)" "unprognostic (2.88e-2)" "unprognostic (1.01e-1)" "unprognostic (8.83e-2)" "unprognostic (1.70e-2)" "unprognostic (2.45e-2)" "unprognostic (7.51e-2)" "unprognostic (1.18e-1)" "unprognostic (1.58e-1)" "unprognostic (5.97e-2)" "unprognostic (2.50e-1)" "unprognostic (2.22e-1)" "unprognostic (1.02e-1)" TMEM107 "JBTS29, MGC10744, MKS13" ENSG00000179029 "Transmembrane protein 107" Q6UX40 17 8172457-8176399 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Developmental protein" "Ciliopathy, Disease variant, Meckel syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 53.5" "Cell type enhanced" "Detected in many" "Epididymal efferent duct ciliated cells: 119.6;Fallopian tube ciliated cells: 212.4;Plasma cells: 179.8;Respiratory ciliated cells: 166.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052555 Approved NA No "Cluster 32: Basophils - Transcription" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 12: Non-specific - Vasculature" "Cluster 42: Non-specific - Unknown function" "Cluster 67: Plasma cells - Plasma cell differentiation" 38 "HPA052555: " "unprognostic (2.24e-1)" "unprognostic (2.07e-1)" "unprognostic (9.32e-2)" "unprognostic (1.37e-1)" "unprognostic (1.30e-2)" "unprognostic (3.40e-2)" "unprognostic (1.25e-2)" "unprognostic (2.07e-1)" "unprognostic (1.60e-3)" "unprognostic (7.30e-2)" "potential prognostic favorable (1.97e-4)" "unprognostic (1.30e-2)" "potential prognostic favorable (1.86e-4)" "unprognostic (7.53e-3)" "potential prognostic unfavorable (7.43e-4)" "unprognostic (2.65e-2)" "unprognostic (2.30e-1)" "unprognostic (3.51e-1)" "unprognostic (3.32e-1)" "unprognostic (3.32e-2)" "unprognostic (7.46e-2)" "unprognostic (6.07e-2)" "potential prognostic unfavorable (1.78e-4)" "unprognostic (2.47e-1)" "unprognostic (1.65e-1)" "unprognostic (1.92e-1)" "unprognostic (7.07e-2)" "unprognostic (7.68e-2)" "unprognostic (2.87e-1)" "unprognostic (2.08e-1)" "unprognostic (1.26e-2)" TMEM108 "CT124, MGC3040" ENSG00000144868 "Transmembrane protein 108" Q6UXF1 3 133038391-133397775 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 32.3;skeletal muscle: 21.7" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 549.5;Astrocytes: 364.5;Bergmann glia: 1263.6;Brain excitatory neurons: 414.7;Cone photoreceptor cells: 2026.6;Ependymal cells: 397.7;Myonuclei: 490.8;Oligodendrocyte progenitor cells: 636.6;Oligodendrocytes: 774.7;Rod photoreceptor cells: 2247.4" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 4143.0" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 21.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 9 "Neuroblastoma: 56.7" "Colon - Colon enteroendocrine cells, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063350 Uncertain Approved "Nucleoli,Vesicles,Plasma membrane,Cytosol" "Intracellular and membrane" "No annotated function" NA NA 23000 "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 79: Photoreceptor cells - Phototransduction" 3 "Plasma membrane, Cytosol" "Nucleoli, Vesicles" "HPA063350: " "unprognostic (3.12e-3)" "unprognostic (1.64e-2)" "unprognostic (1.74e-1)" "unprognostic (1.47e-2)" "unprognostic (2.75e-2)" "unprognostic (2.18e-1)" "unprognostic (2.05e-1)" "unprognostic (2.49e-1)" "potential prognostic favorable (7.23e-4)" "unprognostic (4.65e-2)" "unprognostic (4.11e-3)" "unprognostic (3.34e-1)" "unprognostic (2.94e-1)" "unprognostic (4.55e-1)" "unprognostic (1.50e-1)" "potential prognostic favorable (3.82e-5)" "unprognostic (1.57e-3)" "unprognostic (2.14e-1)" "unprognostic (1.34e-1)" "unprognostic (1.46e-1)" TMEM109 MGC5508 ENSG00000110108 "Transmembrane protein 109" Q9BVC6 11 60914158-60923443 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 146.2;Esophageal apical cells: 182.4;Esophageal basal cells: 132.5;Extravillous trophoblasts: 140.6;Migrating cytotrophoblasts: 126.4" "Cell type enhanced" "Detected in all" "pericyte: 69.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011785, HPA012101" Approved Approved "Nuclear membrane,Endoplasmic reticulum,Vesicles,Actin filaments" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 24: Non-specific - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 18 "Nuclear membrane, Endoplasmic reticulum" "Vesicles, Actin filaments" "HPA011785: , HPA012101: " "unprognostic (3.45e-1)" "unprognostic (1.20e-1)" "unprognostic (5.31e-2)" "unprognostic (2.48e-2)" "unprognostic (6.88e-2)" "unprognostic (7.16e-2)" "unprognostic (3.96e-1)" "unprognostic (1.70e-3)" "unprognostic (5.13e-2)" "unprognostic (1.76e-2)" "potential prognostic favorable (1.78e-6)" "unprognostic (6.62e-3)" "unprognostic (4.03e-1)" "unprognostic (3.36e-2)" "potential prognostic unfavorable (6.20e-4)" "unprognostic (1.70e-1)" "unprognostic (2.18e-3)" "unprognostic (1.96e-1)" "unprognostic (1.16e-1)" "unprognostic (3.97e-1)" "unprognostic (2.76e-1)" "unprognostic (2.14e-1)" "unprognostic (5.70e-2)" "unprognostic (7.00e-3)" "unprognostic (2.31e-1)" "unprognostic (8.99e-2)" "unprognostic (9.90e-2)" "unprognostic (1.30e-1)" "unprognostic (3.98e-2)" "unprognostic (1.56e-1)" "unprognostic (1.59e-1)" TMEM11 "C17orf35, PM1, PMI" ENSG00000178307 "Transmembrane protein 11" P17152 17 21197954-21214176 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 160.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062854 Supported Supported Mitochondria No No "Cluster 7: Non-specific - Innate immune response" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 25: Non-specific - Transcription" "Cluster 42: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 49 Mitochondria "HPA062854: " "unprognostic (3.08e-1)" "unprognostic (1.93e-1)" "unprognostic (1.77e-1)" "unprognostic (1.11e-1)" "unprognostic (3.08e-1)" "unprognostic (2.70e-2)" "unprognostic (4.50e-2)" "unprognostic (2.10e-1)" "unprognostic (2.38e-1)" "unprognostic (3.00e-2)" "unprognostic (5.13e-2)" "unprognostic (4.92e-2)" "unprognostic (4.42e-2)" "unprognostic (2.94e-3)" "unprognostic (3.65e-3)" "potential prognostic unfavorable (8.81e-4)" "unprognostic (4.10e-2)" "unprognostic (3.27e-1)" "unprognostic (1.96e-1)" "unprognostic (7.87e-2)" "unprognostic (2.72e-1)" "unprognostic (3.97e-2)" "unprognostic (5.42e-2)" "unprognostic (3.65e-2)" "unprognostic (1.58e-1)" "unprognostic (1.12e-1)" "unprognostic (1.96e-3)" "unprognostic (1.39e-1)" "unprognostic (4.98e-1)" "unprognostic (3.26e-1)" "unprognostic (1.03e-1)" TMEM114 ENSG00000232258 "Transmembrane protein 114" B3SHH9 16 8537605-8590511 "Disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "seminal vesicle: 15.4" "Cell type enhanced" "Detected in some" "cDC: 1.8;Epicardial cells: 2.3;Epididymal principal cells: 1.9;Gonadotrophs: 2.4;Kupffer cells: 2.0;Lactotrophs: 1.9;Other brain neurons: 4.6;Paneth cells: 3.9;Retinal ganglion cells: 3.9;Retinal horizontal cells: 2.0;Somatotrophs: 1.7;Thyrotrophs: 2.0" "Cell type enhanced" "Detected in some" "fibroblast: 4.7;splatter: 2.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 216 "Bone cancer: 21.6" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "hypothalamus: 6.8" NA NA "Cluster 38: Non-specific - Basic cellular processes" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 1 TMEM115 PL6 ENSG00000126062 "Transmembrane protein 115" Q12893 3 50354750-50359521 "Plasma proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 67.2;Syncytiotrophoblasts: 107.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006319, HPA015497" Supported Supported "Golgi apparatus" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 70: Non-specific - Protein processing" "Cluster 44: Non-specific - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 13 "Golgi apparatus" "CAB006319: , HPA015497: " "unprognostic (1.63e-1)" "unprognostic (1.33e-2)" "unprognostic (1.32e-1)" "unprognostic (1.18e-1)" "unprognostic (2.82e-3)" "unprognostic (7.28e-3)" "unprognostic (1.46e-2)" "unprognostic (1.03e-1)" "unprognostic (2.00e-1)" "unprognostic (2.09e-2)" "potential prognostic favorable (1.97e-4)" "unprognostic (1.86e-3)" "unprognostic (3.83e-3)" "validated prognostic unfavorable (1.63e-8)" "validated prognostic unfavorable (2.05e-6)" "unprognostic (1.39e-1)" "unprognostic (8.14e-2)" "unprognostic (1.68e-1)" "unprognostic (3.46e-1)" "unprognostic (8.03e-2)" "unprognostic (1.10e-1)" "unprognostic (2.37e-2)" "unprognostic (1.57e-2)" "unprognostic (9.51e-2)" "unprognostic (1.93e-1)" "unprognostic (4.94e-2)" "unprognostic (3.43e-1)" "unprognostic (2.99e-2)" "unprognostic (2.06e-1)" "unprognostic (6.37e-3)" "unprognostic (2.43e-2)" TMEM116 FLJ90167 ENSG00000198270 "Transmembrane protein 116" Q8NCL8 12 111931282-112013185 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 56.4;parathyroid gland: 56.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 241.0;Choroid plexus epithelial cells: 263.9;Distal convoluted tubule cells: 131.7;Early primary spermatocytes: 145.9;Late primary spermatocytes: 145.2;Renal collecting duct intercalated cells: 301.8;Renal connecting tubule cells: 130.1" "Cell type enriched" "Detected in all" 4 "choroid plexus epithelial cell: 263.6" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 62.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Lineage enriched" "Detected in all" 4 "T-cells: 19.4" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Minor Salivary Gland - Minor salivary gland ductal cells, Stomach - Parietal cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA040720 Approved Approved Nucleoplasm,Microtubules NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 21: Non-specific - Metabolism" "Cluster 7: Liver cancer - Metabolism" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" Microtubules Nucleoplasm "HPA040720: " "unprognostic (2.34e-1)" "unprognostic (3.18e-1)" "unprognostic (4.85e-2)" "unprognostic (1.45e-3)" "unprognostic (3.05e-2)" "unprognostic (2.28e-2)" "unprognostic (1.65e-2)" "unprognostic (1.44e-1)" "unprognostic (3.18e-1)" "unprognostic (4.14e-2)" "unprognostic (2.27e-2)" "unprognostic (8.64e-2)" "unprognostic (2.20e-3)" "unprognostic (5.00e-2)" "unprognostic (2.15e-2)" "unprognostic (1.13e-1)" "unprognostic (1.12e-2)" "unprognostic (1.41e-1)" "unprognostic (4.66e-2)" "unprognostic (1.30e-1)" "unprognostic (1.91e-1)" "unprognostic (5.37e-2)" "unprognostic (1.92e-1)" "unprognostic (3.59e-2)" "unprognostic (6.68e-2)" "unprognostic (1.94e-1)" "unprognostic (1.07e-2)" "unprognostic (7.74e-2)" "unprognostic (1.64e-1)" "unprognostic (3.45e-2)" "unprognostic (2.92e-1)" TMEM117 DKFZp434K2435 ENSG00000139173 "Transmembrane protein 117" Q9H0C3 12 43835967-44389762 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 1747.6;Corticotrophs: 1118.8;Gonadotrophs: 1027.9;Renal collecting duct intercalated cells: 1893.7;Thyrotrophs: 711.8" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 1449.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046223 Uncertain NA NA "Cluster 24: Non-specific - Transcription" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" "HPA046223: " "unprognostic (1.55e-1)" "unprognostic (1.96e-2)" "unprognostic (2.80e-1)" "unprognostic (1.40e-2)" "unprognostic (5.21e-2)" "unprognostic (1.64e-1)" "unprognostic (2.30e-2)" "unprognostic (2.57e-1)" "unprognostic (8.21e-2)" "unprognostic (2.02e-1)" "potential prognostic favorable (6.29e-4)" "unprognostic (3.38e-2)" "unprognostic (1.56e-1)" "unprognostic (6.73e-3)" "unprognostic (5.09e-2)" "unprognostic (4.51e-2)" "unprognostic (1.50e-2)" "unprognostic (3.83e-3)" "unprognostic (8.85e-3)" "unprognostic (1.17e-1)" "unprognostic (1.38e-1)" "unprognostic (1.42e-1)" "unprognostic (4.49e-1)" "unprognostic (1.91e-1)" "unprognostic (2.04e-1)" "unprognostic (1.02e-2)" "unprognostic (2.10e-1)" "unprognostic (1.86e-1)" "unprognostic (1.16e-1)" "unprognostic (4.90e-2)" TMEM119 OBIF ENSG00000183160 "Transmembrane protein 119" Q4V9L6 12 108589851-108598320 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Biomineralization, Differentiation, Osteogenesis, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 57.2" "Cell type enhanced" "Detected in some" "Decidual stromal cells: 12.1;Early spermatids: 10.9;Fibroblasts: 31.3;Hepatic stellate cells: 12.9;Late spermatids: 12.6;Microglia: 57.8;Neutrophils: 14.5;Pericytes: 29.0;Peritubular myoid cells: 27.8;Smooth muscle cells: 8.1" "Cell type enriched" "Detected in some" 49 "central nervous system macrophage: 64.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Brain cancer: 26.1;Neuroblastoma: 33.5;thyroid cancer: 27.8" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Fibroblasts, Breast - Fibroblasts, Kidney - Fibroblasts, Pituitary gland - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblasts_1, Stomach - Fibroblasts, Testis - Peritubular cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051870, HPA052650" Enhanced "Intracellular and membrane" Other NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" "HPA051870: , HPA052650: " "unprognostic (3.37e-3)" "unprognostic (1.34e-1)" "unprognostic (1.20e-1)" "unprognostic (1.83e-1)" "unprognostic (2.67e-1)" "unprognostic (2.17e-1)" "unprognostic (4.90e-1)" "unprognostic (2.05e-1)" "unprognostic (7.50e-2)" "unprognostic (1.00e-2)" "unprognostic (3.32e-2)" "unprognostic (2.10e-1)" "potential prognostic unfavorable (9.04e-5)" "unprognostic (1.74e-2)" "unprognostic (3.58e-2)" "unprognostic (2.97e-2)" "unprognostic (1.75e-1)" "unprognostic (3.19e-2)" "unprognostic (2.47e-1)" "unprognostic (2.19e-3)" "unprognostic (4.95e-2)" "unprognostic (1.51e-1)" "unprognostic (2.99e-2)" "unprognostic (1.04e-1)" "unprognostic (8.47e-2)" "unprognostic (5.66e-2)" "unprognostic (9.09e-3)" "unprognostic (1.19e-2)" "unprognostic (4.13e-3)" "unprognostic (4.26e-2)" "unprognostic (1.69e-1)" TMEM120A "NET29, TACAN, TMPIT" ENSG00000189077 "Transmembrane protein 120A" Q9BXJ8 7 75986831-75994656 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Late spermatids: 1752.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 223.9" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 70: Non-specific - Protein processing" "Cluster 49: Hindbrain - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 28 "unprognostic (2.32e-1)" "unprognostic (3.34e-2)" "unprognostic (2.43e-2)" "unprognostic (9.98e-3)" "unprognostic (5.92e-3)" "unprognostic (8.24e-2)" "unprognostic (1.69e-1)" "unprognostic (4.37e-3)" "unprognostic (5.94e-2)" "unprognostic (1.47e-2)" "unprognostic (3.88e-2)" "unprognostic (5.28e-2)" "unprognostic (4.10e-3)" "unprognostic (1.45e-2)" "potential prognostic unfavorable (1.17e-5)" "unprognostic (1.43e-2)" "unprognostic (3.54e-3)" "unprognostic (1.68e-1)" "unprognostic (2.09e-1)" "unprognostic (5.45e-2)" "unprognostic (7.40e-2)" "unprognostic (4.84e-2)" "unprognostic (2.52e-1)" "unprognostic (1.02e-1)" "unprognostic (1.25e-2)" "unprognostic (1.01e-3)" "unprognostic (1.73e-2)" "unprognostic (4.81e-3)" "unprognostic (1.02e-1)" "unprognostic (1.25e-1)" "unprognostic (2.74e-2)" TMEM120B ENSG00000188735 "Transmembrane protein 120B" A0PK00 12 121712752-121783001 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 45.9" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 267.1;Myonuclei: 274.9;Platelets: 176.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014066 Uncertain Approved "Nucleoli fibrillar center,Cytosol" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 64: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 1: Neuronal - Visual perception" "Cluster 51: Secretory epithelial cells - Mixed function" 54 "Nucleoli fibrillar center" Cytosol "HPA014066: " "unprognostic (1.73e-1)" "unprognostic (2.60e-3)" "unprognostic (6.11e-2)" "unprognostic (6.23e-3)" "unprognostic (1.73e-1)" "unprognostic (4.71e-1)" "unprognostic (7.78e-2)" "unprognostic (1.98e-1)" "unprognostic (6.45e-2)" "unprognostic (3.56e-1)" "unprognostic (2.34e-2)" "unprognostic (4.46e-2)" "unprognostic (2.95e-3)" "potential prognostic unfavorable (9.01e-6)" "unprognostic (2.46e-1)" "unprognostic (2.09e-1)" "unprognostic (2.88e-2)" "unprognostic (1.58e-1)" "unprognostic (8.67e-3)" "unprognostic (1.42e-2)" "unprognostic (1.34e-1)" "unprognostic (5.43e-2)" "unprognostic (8.44e-2)" "unprognostic (1.39e-1)" "unprognostic (2.10e-2)" "unprognostic (3.92e-3)" "unprognostic (5.15e-2)" "unprognostic (7.77e-3)" "unprognostic (3.12e-1)" "potential prognostic unfavorable (1.28e-6)" "unprognostic (1.80e-1)" TMEM121 "hole, MGC4659, TMEM121A" ENSG00000184986 "Transmembrane protein 121" Q9BTD3 14 105526583-105530202 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.8" "Cell type enhanced" "Detected in many" "Ependymal cells: 17.9;Epididymal efferent duct ciliated cells: 23.1;Epididymal principal cells: 24.0;Fallopian tube ciliated cells: 27.1;Müller glia: 16.6;Oligodendrocyte progenitor cells: 25.4;Respiratory ciliated cells: 35.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 2.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049857 Uncertain Approved Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 78: Brain - Neuronal signaling" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 12 Cytosol "HPA049857: " "unprognostic (2.79e-2)" "unprognostic (5.30e-2)" "unprognostic (2.99e-1)" "unprognostic (1.10e-1)" "unprognostic (1.51e-1)" "unprognostic (8.06e-2)" "unprognostic (1.20e-1)" "unprognostic (1.81e-2)" "unprognostic (6.55e-2)" "unprognostic (4.19e-3)" "unprognostic (4.91e-2)" "unprognostic (1.13e-1)" "unprognostic (9.46e-2)" "unprognostic (2.95e-2)" "potential prognostic favorable (4.34e-4)" "unprognostic (1.14e-1)" "unprognostic (8.10e-2)" "unprognostic (1.24e-1)" "unprognostic (5.21e-2)" "unprognostic (2.49e-1)" "unprognostic (1.57e-3)" "unprognostic (2.65e-1)" TMEM121B CECR6 ENSG00000183307 "Transmembrane protein 121B" Q9BXQ6 22 17116297-17121367 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.4;prostate: 6.2" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 6.0;Brain inhibitory neurons: 5.1;Corticotrophs: 4.8;Early spermatids: 14.9;Hofbauer cells: 5.3;Late spermatids: 11.0;Microglia: 6.3;Monocyte progenitors: 4.8;monocytes: 3.8;Neutrophils: 11.9;Oligodendrocyte progenitor cells: 8.0;Prostatic glandular cells: 5.9;Retinal amacrine cells: 4.1" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Prostate Adenocarcinoma (TCGA): 10.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.1;neutrophil: 1.7" "Group enriched" "Detected in many" 7 "granulocytes: 1.7;monocytes: 1.1" "Cancer enhanced" "Detected in some" "Leukemia: 3.8;Neuroblastoma: 4.4" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Colon - Macrophages, Heart muscle - Cardiomyocytes, Kidney - Macrophages, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Corticotropes, Prostate - Prostate glandular cells, Spleen - Neutrophils_2, Testis - Late spermatids, Thyroid gland - Macrophages" "Low region specificity" "Detected in all" HPA068790 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" Vesicles "Nucleoplasm, Plasma membrane" "HPA068790: " "unprognostic (1.86e-1)" "potential prognostic favorable (9.32e-4)" "unprognostic (3.13e-2)" "unprognostic (1.95e-1)" TMEM123 "KCT3, PORIMIN" ENSG00000152558 "Transmembrane protein 123" Q8N131 11 102396332-102470384 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Cell type enhanced" "Detected in all" "endothelial cell: 271.3;ependymal cell: 304.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026001, HPA062862" Approved "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 11: White matter - Signal transduction" "Cluster 24: Non-specific - Unknown function" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 7 "Golgi apparatus" "Vesicles, Cytosol" "CAB026001: , HPA062862: " "unprognostic (7.41e-3)" "unprognostic (1.82e-1)" "unprognostic (1.03e-1)" "unprognostic (4.75e-3)" "unprognostic (2.37e-1)" "unprognostic (2.42e-1)" "unprognostic (6.39e-2)" "unprognostic (2.02e-3)" "unprognostic (3.29e-2)" "unprognostic (1.35e-2)" "potential prognostic favorable (6.89e-5)" "unprognostic (9.96e-3)" "unprognostic (9.25e-2)" "unprognostic (1.18e-1)" "unprognostic (1.44e-1)" "unprognostic (1.35e-2)" "unprognostic (4.37e-3)" "unprognostic (4.53e-1)" "unprognostic (4.35e-1)" "unprognostic (2.00e-1)" "unprognostic (5.37e-2)" "potential prognostic unfavorable (3.63e-4)" "unprognostic (4.27e-1)" "unprognostic (6.56e-2)" "unprognostic (8.13e-3)" "unprognostic (1.72e-2)" "unprognostic (1.43e-3)" "unprognostic (1.41e-1)" "unprognostic (4.49e-1)" "unprognostic (2.33e-3)" "unprognostic (2.44e-1)" TMEM125 MGC17299 ENSG00000179178 "Transmembrane protein 125" Q96AQ2 1 43269983-43274002 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 64.4;lung: 71.4;pancreas: 85.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 155.2;Alveolar cells type 2: 196.8;Breast lactating cells: 94.1;Enterocytes: 147.1;Esophageal apical cells: 81.8;Oligodendrocytes: 86.3;Respiratory ciliated cells: 77.4;Transitional alveolar cells: 123.3" "Cell type enriched" "Detected in many" 4 "oligodendrocyte: 111.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Liver - Cholangiocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Somatotropes, Prostate - Prostate glandular cells, Skin - Keratinocyte (granular), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015796 Approved Midbody,Cytosol Yes NA "Cluster 60: Stomach - Digestion" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 81: Alveolar cells - Lung function" "Midbody, Cytosol" "HPA015796: " "unprognostic (1.87e-1)" "unprognostic (5.59e-2)" "unprognostic (7.20e-2)" "unprognostic (1.36e-1)" "unprognostic (3.45e-2)" "unprognostic (3.75e-2)" "unprognostic (1.80e-1)" "unprognostic (2.08e-1)" "unprognostic (7.76e-2)" "potential prognostic favorable (3.30e-4)" "validated prognostic favorable (5.72e-11)" "validated prognostic favorable (2.24e-5)" "potential prognostic favorable (8.27e-5)" "unprognostic (3.70e-2)" "unprognostic (1.19e-1)" "potential prognostic favorable (1.23e-6)" "unprognostic (9.52e-2)" "unprognostic (4.20e-3)" "unprognostic (3.59e-2)" "unprognostic (2.12e-1)" "unprognostic (6.71e-2)" "unprognostic (9.38e-2)" "unprognostic (1.13e-2)" "unprognostic (5.15e-2)" "unprognostic (9.55e-2)" "unprognostic (5.03e-2)" "unprognostic (3.78e-1)" "unprognostic (2.22e-2)" "unprognostic (2.05e-1)" "unprognostic (2.05e-1)" "unprognostic (3.40e-1)" TMEM126A "DKFZp586C1924, OPA7" ENSG00000171202 "Transmembrane protein 126A" Q9H061 11 85647967-85656547 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric progenitor cells: 211.5;Late primary spermatocytes: 296.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046648 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cellular respiration" "Cluster 27: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 27 Cytosol Nucleoplasm "HPA046648: " "unprognostic (4.67e-2)" "unprognostic (2.04e-3)" "unprognostic (2.64e-2)" "unprognostic (1.63e-1)" "unprognostic (3.02e-2)" "unprognostic (3.35e-1)" "unprognostic (5.13e-1)" "unprognostic (4.14e-1)" "unprognostic (4.79e-2)" "unprognostic (1.99e-2)" "potential prognostic favorable (2.05e-5)" "unprognostic (8.06e-2)" "potential prognostic favorable (1.11e-4)" "potential prognostic unfavorable (1.84e-5)" "unprognostic (9.63e-3)" "unprognostic (1.46e-2)" "unprognostic (2.40e-2)" "unprognostic (1.37e-1)" "unprognostic (2.89e-1)" "unprognostic (3.23e-2)" "unprognostic (1.22e-2)" "potential prognostic unfavorable (9.23e-4)" "unprognostic (5.20e-2)" "unprognostic (8.60e-2)" "unprognostic (2.34e-2)" "unprognostic (2.16e-1)" "unprognostic (1.41e-2)" "unprognostic (1.67e-1)" "unprognostic (1.98e-1)" "unprognostic (1.15e-1)" "unprognostic (2.31e-1)" TMEM126B HT007 ENSG00000171204 "Transmembrane protein 126B" Q8IUX1 11 85628573-85636539 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Chaperone "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric progenitor cells: 147.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014480, HPA019186" Uncertain Supported Mitochondria NA NA "Cluster 1: T-cells - Unknown function" "Cluster 35: Non-specific - Mixed function" "Cluster 27: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 2 Mitochondria "HPA014480: , HPA019186: " "unprognostic (1.11e-3)" "unprognostic (1.26e-3)" "unprognostic (3.03e-2)" "unprognostic (3.09e-1)" "unprognostic (2.19e-1)" "unprognostic (4.70e-3)" "unprognostic (3.74e-1)" "unprognostic (1.80e-1)" "unprognostic (4.27e-2)" "unprognostic (7.51e-3)" "unprognostic (3.06e-1)" "unprognostic (1.68e-1)" "unprognostic (3.95e-1)" "unprognostic (9.61e-3)" "unprognostic (2.68e-1)" "unprognostic (2.04e-3)" "unprognostic (7.47e-2)" "unprognostic (4.21e-1)" "unprognostic (7.56e-2)" "unprognostic (6.35e-2)" "unprognostic (1.45e-1)" "unprognostic (2.07e-2)" "potential prognostic unfavorable (7.51e-4)" "unprognostic (1.13e-2)" "unprognostic (6.73e-3)" "unprognostic (1.82e-2)" "unprognostic (1.37e-2)" "unprognostic (2.35e-1)" "unprognostic (1.02e-1)" "unprognostic (7.69e-3)" "unprognostic (3.16e-1)" TMEM127 "FLJ20507, FLJ22257" ENSG00000135956 "Transmembrane protein 127" O75204 2 96248514-96265997 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 166.5;Neutrophils: 222.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 35: Non-specific - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 29: Neutrophils - Innate immune cellular maintenance" "unprognostic (1.77e-2)" "unprognostic (2.20e-3)" "unprognostic (1.31e-1)" "potential prognostic unfavorable (8.01e-4)" "unprognostic (2.49e-1)" "unprognostic (4.57e-2)" "unprognostic (2.90e-1)" "unprognostic (1.16e-3)" "unprognostic (2.68e-1)" "unprognostic (2.41e-1)" "potential prognostic favorable (1.09e-6)" "unprognostic (1.78e-3)" "unprognostic (4.67e-2)" "unprognostic (3.71e-3)" "unprognostic (1.45e-2)" "unprognostic (1.31e-1)" "unprognostic (4.10e-3)" "unprognostic (7.29e-2)" "unprognostic (1.85e-1)" "unprognostic (1.71e-2)" "unprognostic (2.16e-3)" "unprognostic (8.89e-2)" "unprognostic (6.64e-2)" "unprognostic (1.79e-1)" "unprognostic (4.42e-2)" "unprognostic (1.49e-1)" "unprognostic (1.67e-1)" "unprognostic (3.10e-1)" "unprognostic (2.30e-1)" "unprognostic (1.48e-1)" "unprognostic (2.76e-1)" TMEM128 MGC13159 ENSG00000132406 "Transmembrane protein 128" Q5BJH2 4 4235542-4248223 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Parietal cells: 91.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044809 Uncertain NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 97: Non-specific - Cellular respiration" 2 "HPA044809: " "unprognostic (2.74e-2)" "unprognostic (8.56e-2)" "unprognostic (1.17e-2)" "unprognostic (1.99e-1)" "unprognostic (6.95e-2)" "unprognostic (1.04e-2)" "unprognostic (3.19e-2)" "unprognostic (1.83e-1)" "unprognostic (2.40e-1)" "unprognostic (2.98e-1)" "potential prognostic favorable (1.14e-5)" "unprognostic (2.57e-2)" "unprognostic (1.47e-1)" "unprognostic (3.37e-2)" "unprognostic (6.95e-2)" "unprognostic (1.85e-1)" "unprognostic (2.09e-1)" "unprognostic (3.08e-2)" "unprognostic (9.68e-2)" "unprognostic (2.03e-1)" "unprognostic (8.96e-2)" "unprognostic (2.66e-1)" "unprognostic (1.36e-1)" "unprognostic (7.62e-2)" "unprognostic (1.27e-1)" "unprognostic (4.09e-2)" "unprognostic (1.76e-1)" "unprognostic (2.15e-1)" "unprognostic (3.35e-1)" "unprognostic (2.32e-1)" "unprognostic (2.54e-1)" TMEM129 D4S2561E ENSG00000168936 "Transmembrane protein 129, E3 ubiquitin ligase" A0AVI4 4 1715952-1721358 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway, Unfolded protein response" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 44: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 2 "unprognostic (2.06e-3)" "unprognostic (1.73e-1)" "unprognostic (8.63e-2)" "unprognostic (8.70e-2)" "unprognostic (2.02e-2)" "unprognostic (2.84e-2)" "unprognostic (3.26e-1)" "unprognostic (3.47e-1)" "unprognostic (2.38e-2)" "unprognostic (8.64e-2)" "potential prognostic favorable (1.65e-4)" "unprognostic (1.53e-3)" "potential prognostic favorable (1.53e-11)" "unprognostic (3.68e-3)" "unprognostic (2.34e-1)" "unprognostic (1.69e-1)" "unprognostic (1.71e-1)" "unprognostic (2.92e-2)" "unprognostic (5.61e-1)" "unprognostic (4.06e-2)" "unprognostic (1.43e-2)" "unprognostic (4.92e-3)" "unprognostic (2.18e-2)" "unprognostic (1.95e-2)" "unprognostic (3.76e-1)" "unprognostic (6.81e-2)" "unprognostic (1.98e-1)" "unprognostic (1.72e-1)" "unprognostic (2.72e-1)" "unprognostic (3.39e-2)" "unprognostic (1.96e-2)" TMEM130 "DKFZp761L1417, FLJ42643" ENSG00000166448 "Transmembrane protein 130" Q8N3G9 7 98846488-98870771 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 167.1;pituitary gland: 94.8" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 159.6;Brain excitatory neurons: 81.8;Brain inhibitory neurons: 92.5;Corticotrophs: 228.3;Gonadotrophs: 119.8;Lactotrophs: 140.7;Other brain neurons: 142.8;Retinal amacrine cells: 49.9;Retinal bipolar cells: 102.4;Sertoli cells: 62.6;Somatotrophs: 124.5;Thyrotrophs: 132.9" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 21.4;Kidney Renal Papillary Cell Carcinoma (TCGA): 27.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.3" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.3" "Cancer enhanced" "Detected in many" "Neuroblastoma: 12.7" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Prostate - Fibroblasts, Stomach - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012928 Uncertain Supported "Golgi apparatus" NA NA 8100 "Cluster 73: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 10 "Golgi apparatus" "HPA012928: " "unprognostic (4.11e-3)" "unprognostic (2.81e-2)" "unprognostic (2.60e-1)" "potential prognostic favorable (6.62e-4)" "unprognostic (9.47e-2)" "unprognostic (6.14e-3)" "unprognostic (2.09e-1)" "unprognostic (6.32e-2)" "unprognostic (1.38e-1)" "unprognostic (6.56e-2)" "unprognostic (1.44e-1)" "potential prognostic favorable (3.43e-4)" "unprognostic (1.65e-1)" "unprognostic (1.48e-1)" "unprognostic (4.33e-1)" "unprognostic (3.05e-2)" "unprognostic (4.74e-3)" "unprognostic (2.11e-2)" "unprognostic (4.47e-2)" "unprognostic (1.84e-1)" "unprognostic (2.35e-3)" "unprognostic (1.81e-2)" "unprognostic (6.01e-2)" "unprognostic (8.06e-3)" "unprognostic (4.06e-3)" TMEM131 "CC28, KIAA0257, PRO1048, RW1, YR-23" ENSG00000075568 "Transmembrane protein 131" Q92545 2 97756333-97995948 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Myonuclei: 606.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017678, HPA017682" Approved Uncertain "Vesicles,Intermediate filaments" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 55: Lymphoma - Immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 32 "Vesicles, Intermediate filaments" "HPA017678: , HPA017682: " "unprognostic (2.96e-2)" "unprognostic (9.01e-3)" "unprognostic (9.58e-3)" "unprognostic (6.04e-2)" "unprognostic (9.87e-2)" "unprognostic (1.18e-1)" "unprognostic (2.15e-1)" "unprognostic (2.63e-2)" "unprognostic (1.58e-1)" "unprognostic (7.07e-2)" "potential prognostic favorable (1.70e-5)" "unprognostic (1.08e-1)" "unprognostic (1.67e-1)" "unprognostic (4.26e-3)" "unprognostic (4.53e-2)" "unprognostic (4.08e-2)" "unprognostic (4.20e-3)" "unprognostic (5.03e-2)" "unprognostic (8.99e-3)" "unprognostic (4.40e-2)" "unprognostic (2.21e-2)" "unprognostic (6.43e-2)" "unprognostic (3.03e-2)" "unprognostic (1.83e-1)" "unprognostic (1.52e-1)" "unprognostic (3.46e-1)" "unprognostic (5.92e-2)" "unprognostic (1.30e-1)" "unprognostic (2.83e-1)" "unprognostic (1.91e-1)" "unprognostic (4.07e-1)" TMEM131L "DKFZp586H1322, KIAA0922" ENSG00000121210 "Transmembrane 131 like" A2VDJ0 4 153466346-153636711 "Predicted membrane proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 46.7;lymphoid tissue: 45.0" "Cell type enhanced" "Detected in many" "Adipocytes: 402.5;B-cells: 542.1;Myonuclei: 811.5;Neutrophil progenitors: 618.1;Neutrophils: 623.6;Thymocytes: 328.6;Vascular smooth muscle cells: 327.7" "Cell type enhanced" "Detected in all" "leukocyte: 405.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Leukemia: 34.5;lymphoma: 59.7" "Adrenal gland - Fibroblasts, Liver - Hepatocytes, Prostate - Smooth muscle cells, Spleen - B-cells (Spleen), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043472, HPA048443" Uncertain Approved "Nucleoli fibrillar center,Vesicles" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 34: Non-specific - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 1 Vesicles "Nucleoli fibrillar center" "HPA043472: , HPA048443: " "unprognostic (4.37e-2)" "unprognostic (6.46e-2)" "potential prognostic favorable (6.94e-4)" "unprognostic (3.38e-1)" "unprognostic (7.13e-2)" "unprognostic (1.37e-1)" "unprognostic (2.41e-2)" "unprognostic (4.07e-3)" "unprognostic (1.33e-1)" "validated prognostic favorable (8.17e-5)" "validated prognostic favorable (9.27e-5)" "unprognostic (1.16e-1)" "unprognostic (4.43e-2)" "unprognostic (9.89e-2)" "unprognostic (7.42e-2)" "unprognostic (1.27e-1)" "unprognostic (3.04e-1)" "unprognostic (3.98e-2)" "unprognostic (4.25e-1)" "unprognostic (4.29e-2)" "unprognostic (2.42e-3)" "unprognostic (7.68e-2)" "unprognostic (2.66e-1)" "unprognostic (1.00e-2)" "unprognostic (5.67e-2)" "unprognostic (1.91e-1)" "unprognostic (1.66e-1)" "unprognostic (5.36e-2)" "unprognostic (1.36e-1)" TMEM132A "FLJ20539, GBP, HSPA5BP1" ENSG00000006118 "Transmembrane protein 132A" Q24JP5 11 60924460-60937159 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 105.8;choroid plexus: 107.2" "Cell type enhanced" "Detected in many" "Astrocytes: 101.1;Müller glia: 185.3;Retinal amacrine cells: 59.3;Retinal horizontal cells: 136.2;Retinal pigment epithelial cells: 132.2;Rod photoreceptor cells: 65.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Uterine Corpus Endometrial Carcinoma (TCGA): 215.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051979, HPA060492" Enhanced Supported Approved Mitochondria No No 1600000 "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 27: Breast cancer - Unknown function" "Cluster 11: Muller glia cells - Retinal homeostasis" Mitochondria "HPA051979: , HPA060492: " "unprognostic (1.25e-1)" "unprognostic (2.95e-2)" "unprognostic (1.47e-1)" "unprognostic (7.09e-2)" "unprognostic (1.87e-1)" "unprognostic (2.22e-2)" "unprognostic (4.63e-2)" "unprognostic (3.33e-2)" "unprognostic (3.41e-1)" "unprognostic (1.07e-3)" "validated prognostic unfavorable (1.72e-6)" "validated prognostic unfavorable (3.25e-4)" "unprognostic (1.80e-2)" "unprognostic (6.03e-3)" "unprognostic (4.22e-2)" "unprognostic (2.25e-2)" "unprognostic (1.02e-2)" "unprognostic (1.10e-1)" "unprognostic (1.83e-1)" "unprognostic (9.59e-2)" "unprognostic (1.86e-1)" "unprognostic (1.54e-1)" "unprognostic (1.01e-3)" "unprognostic (4.61e-2)" "unprognostic (1.10e-1)" "unprognostic (2.53e-2)" "unprognostic (2.56e-1)" "unprognostic (2.72e-1)" "unprognostic (1.09e-2)" "unprognostic (7.80e-2)" "unprognostic (6.87e-2)" TMEM132B "KIAA1786, KIAA1906" ENSG00000139364 "Transmembrane protein 132B" Q14DG7 12 125186386-125662377 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 12.5" "Cell type enhanced" "Detected in many" "Astrocytes: 248.5;Brain excitatory neurons: 367.6;Brain inhibitory neurons: 428.7;Late spermatids: 164.4;Oligodendrocyte progenitor cells: 390.5;Oligodendrocytes: 245.7;Other brain neurons: 265.3;Pituicytes/FSCs: 241.2;Retinal amacrine cells: 172.3;Schwann cells: 185.7" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in single" 9 "Glioblastoma Multiforme (TCGA): 7.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Bone cancer: 7.4" "Kidney - Fibroblasts, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035661, HPA035662" Uncertain NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" "HPA035661: , HPA035662: " "unprognostic (9.60e-2)" "unprognostic (4.13e-2)" "unprognostic (1.63e-2)" TMEM132C "DKFZp761O2018, PPP1R152" ENSG00000181234 "Transmembrane protein 132C" Q8N3T6 12 128267170-128707911 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 28.6" "Cell type enhanced" "Detected in many" "Adipocytes: 997.2;Choroid plexus epithelial cells: 763.0;Cone photoreceptor cells: 196.7;Endometrial stromal cells: 362.1;Oligodendrocyte progenitor cells: 806.3;Retinal bipolar cells: 339.1" "Cell type enhanced" "Detected in all" "fibroblast: 1153.2;oligodendrocyte precursor cell: 992.9" "Group enriched" "Detected in some" 5 "Glioblastoma Multiforme (TCGA): 2.6;Ovary Serous Cystadenocarcinoma (TCGA): 6.1;Testicular Germ Cell Tumor (TCGA): 7.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 19 "gdT-cell: 1.8" "Lineage enriched" "Detected in single" 19 "T-cells: 1.8" "Group enriched" "Detected in some" 5 "Neuroblastoma: 2.7;Rhabdoid: 2.5;Sarcoma: 3.4" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Fibroblasts, Breast - Adipocytes (Breast), Minor Salivary Gland - Adipocytes (Minor salivary gland), Pituitary gland - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015633 Approved "Plasma membrane,Centrosome,Cytosol" NA NA 6800000 "Cluster 24: Non-specific - Transcription" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 54: Non-specific - Transcription" "Cluster 89: Adipocytes - Lipid metabolism" "Centrosome, Cytosol" "Plasma membrane" "HPA015633: " "potential prognostic favorable (3.17e-4)" "unprognostic (3.26e-1)" "unprognostic (9.75e-3)" "unprognostic (9.18e-2)" "unprognostic (2.13e-1)" "unprognostic (2.09e-2)" "unprognostic (2.13e-1)" TMEM132D "KIAA1944, MOLT, PPP1R153" ENSG00000151952 "Transmembrane protein 132D" Q14C87 12 129071725-129904025 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 9 "brain: 6.7" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 268.2;Brain inhibitory neurons: 359.3;Gonadotrophs: 231.8;Lactotrophs: 189.3;Neuroendocrine cells: 155.7;Oligodendrocyte progenitor cells: 834.5;Other brain neurons: 335.2;Pancreatic islet cells: 753.7;Pituitary stem cells: 246.2;Prostatic glandular cells: 164.5;Retinal bipolar cells: 127.6" "Cell type enhanced" "Detected in all" "LAMP5-LHX6 and Chandelier: 1349.3" "Cancer enhanced" "Detected in some" "Thyroid Carcinoma (TCGA): 1.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "thyroid cancer: 1.8" "Adrenal gland - Adrenal medulla cells, Pancreas - Alpha cells, Pancreas - Beta cells, Prostate - Prostate glandular cells, Spleen - Neutrophils_2, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA010739 Approved NA NA 57000 "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 2 "HPA010739: " "unprognostic (1.44e-1)" "unprognostic (1.20e-2)" "unprognostic (9.55e-3)" TMEM132E DFNB99 ENSG00000181291 "Transmembrane protein 132E" Q6IEE7 17 34579487-34639318 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 12.7" "Cell type enhanced" "Detected in some" "Astrocytes: 8.1;Brain excitatory neurons: 8.7;Brain inhibitory neurons: 9.4;cDC: 4.6;Differentiating spermatogonia: 5.4;Early primary spermatocytes: 7.1;Hepatic stellate cells: 6.5;Kupffer cells: 11.3;Late spermatids: 10.7;Oligodendrocyte progenitor cells: 17.6;Other brain neurons: 16.5;Proximal tubule cells: 11.9;Retinal amacrine cells: 21.5" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 9.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Sarcoma: 3.9" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070608 Approved Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus,Cytosol" NA NA 110000 "Cluster 27: Cerebellum - Synaptic function" "Cluster 44: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 109: Neurons - Neuronal signaling" "Nucleoplasm, Golgi apparatus" "Nuclear bodies, Cytosol" "HPA070608: " "unprognostic (3.03e-1)" "unprognostic (2.63e-1)" "unprognostic (2.42e-1)" "unprognostic (2.75e-1)" "unprognostic (5.88e-2)" "unprognostic (1.09e-1)" TMEM134 FLJ21749 ENSG00000172663 "Transmembrane protein 134" Q9H6X4 11 67461710-67469272 "Predicted membrane proteins, Transporters" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 872.8;Esophageal basal cells: 296.1;Esophageal suprabasal cells: 584.2;Suprabasal keratinocytes: 230.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Prostate - Prostate glandular cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043744 Approved Supported Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Ribosome" "Cluster 24: Non-specific - Unknown function" "Cluster 85: Squamous epithelial cells - Keratinization" Cytosol "HPA043744: " "unprognostic (1.35e-2)" "unprognostic (2.61e-2)" "unprognostic (2.50e-1)" "unprognostic (1.17e-1)" "unprognostic (9.76e-2)" "unprognostic (2.69e-1)" "unprognostic (1.11e-1)" "unprognostic (2.10e-1)" "unprognostic (1.18e-1)" "unprognostic (1.27e-2)" "unprognostic (7.01e-2)" "unprognostic (1.12e-2)" "potential prognostic favorable (5.10e-5)" "unprognostic (1.53e-1)" "unprognostic (2.32e-1)" "unprognostic (8.94e-2)" "unprognostic (3.30e-2)" "unprognostic (9.46e-2)" "unprognostic (1.49e-1)" "unprognostic (1.59e-2)" "unprognostic (2.50e-1)" "unprognostic (2.17e-2)" "unprognostic (6.89e-3)" "unprognostic (4.62e-1)" "unprognostic (4.10e-2)" "unprognostic (1.29e-1)" "unprognostic (2.42e-1)" "unprognostic (1.67e-2)" "unprognostic (2.12e-1)" "unprognostic (8.78e-3)" "unprognostic (2.29e-1)" TMEM135 FLJ22104 ENSG00000166575 "Transmembrane protein 135" Q86UB9 11 87037844-87328824 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 782.8;Sertoli cells: 561.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Spleen - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056685, HPA069473" Uncertain Supported Vesicles NA NA "Cluster 24: Non-specific - Transcription" "Cluster 76: Non-specific - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 89: Adipocytes - Lipid metabolism" Vesicles "HPA056685: , HPA069473: " "unprognostic (8.06e-2)" "unprognostic (5.00e-3)" "unprognostic (6.96e-3)" "potential prognostic unfavorable (4.16e-4)" "unprognostic (2.57e-2)" "unprognostic (1.20e-1)" "unprognostic (1.05e-1)" "unprognostic (5.29e-2)" "unprognostic (9.22e-2)" "potential prognostic unfavorable (4.58e-4)" "potential prognostic favorable (1.31e-9)" "unprognostic (1.67e-3)" "unprognostic (4.04e-3)" "unprognostic (3.46e-3)" "unprognostic (1.48e-1)" "unprognostic (9.38e-2)" "unprognostic (6.33e-3)" "unprognostic (4.96e-2)" "unprognostic (1.80e-1)" "unprognostic (9.52e-2)" "unprognostic (5.93e-2)" "unprognostic (4.82e-2)" "unprognostic (3.89e-2)" "unprognostic (1.25e-1)" "unprognostic (2.28e-2)" "unprognostic (1.09e-1)" "unprognostic (1.25e-2)" "unprognostic (1.76e-2)" "unprognostic (2.33e-1)" "unprognostic (3.02e-2)" "unprognostic (6.29e-2)" TMEM138 "HSPC196, JBTS16" ENSG00000149483 "Transmembrane protein 138" Q9NPI0 11 61361964-61377890 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adrenal cortex cells: 81.6;Rod photoreceptor cells: 134.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042373 Approved Approved "Microtubules,Primary cilium" NA Yes "Cluster 29: Non-specific - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 9: Non-specific - Receptor signaling" "Cluster 24: Non-specific - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" "Microtubules, Primary cilium" "HPA042373: " "unprognostic (2.80e-1)" "unprognostic (1.55e-3)" "unprognostic (1.90e-1)" "unprognostic (4.67e-3)" "unprognostic (9.21e-2)" "unprognostic (2.26e-1)" "unprognostic (4.19e-3)" "unprognostic (4.33e-2)" "unprognostic (3.30e-1)" "unprognostic (1.44e-1)" "potential prognostic unfavorable (9.44e-4)" "unprognostic (3.95e-2)" "unprognostic (2.32e-1)" "unprognostic (2.61e-3)" "unprognostic (5.28e-2)" "unprognostic (2.47e-1)" "unprognostic (1.48e-1)" "unprognostic (5.93e-2)" "unprognostic (1.71e-1)" "unprognostic (1.04e-1)" "unprognostic (1.75e-1)" "unprognostic (8.47e-2)" "unprognostic (2.62e-2)" "unprognostic (3.96e-1)" "unprognostic (1.72e-1)" "unprognostic (1.92e-1)" "unprognostic (2.81e-2)" "unprognostic (2.11e-1)" "unprognostic (6.83e-2)" "unprognostic (7.43e-2)" "unprognostic (1.63e-1)" TMEM139 FLJ90586 ENSG00000178826 "Transmembrane protein 139" Q8IV31 7 143279957-143288048 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 31.8;kidney: 30.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 40.9;Breast myoepithelial cells: 30.1;Cholangiocytes: 24.3;Colonocytes: 40.9;Cytotrophoblasts: 37.2;Endometrial luminal cells: 27.7;Endometrial secretory cells: 43.1;Enterocytes: 81.4;Late spermatids: 23.5" "Group enriched" "Detected in some" 5 "choroid plexus epithelial cell: 6.3;oligodendrocyte: 7.9" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 43.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Skin - Eccrine sweat gland cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA036982, HPA036983" Approved Approved "Plasma membrane,Focal adhesion sites" NA NA "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 30: White matter - Myelination" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 35 "Plasma membrane" "Focal adhesion sites" "HPA036982: , HPA036983: " "unprognostic (3.95e-2)" "unprognostic (1.77e-1)" "unprognostic (7.44e-2)" "unprognostic (1.34e-1)" "unprognostic (1.16e-1)" "unprognostic (9.51e-2)" "unprognostic (5.03e-2)" "unprognostic (2.08e-2)" "unprognostic (1.11e-1)" "validated prognostic favorable (1.23e-8)" "validated prognostic favorable (1.58e-4)" "unprognostic (2.40e-3)" "unprognostic (3.53e-2)" "unprognostic (1.61e-1)" "unprognostic (7.30e-2)" "unprognostic (1.48e-1)" "unprognostic (1.42e-1)" "unprognostic (1.59e-1)" "unprognostic (3.51e-1)" "unprognostic (1.38e-2)" "potential prognostic unfavorable (2.27e-5)" "unprognostic (5.23e-2)" "unprognostic (1.34e-2)" "unprognostic (2.08e-2)" "unprognostic (4.19e-2)" "unprognostic (1.11e-1)" "unprognostic (7.55e-2)" "unprognostic (7.83e-2)" "unprognostic (6.29e-2)" TMEM140 FLJ11000 ENSG00000146859 "Transmembrane protein 140" Q9NV12 7 135148072-135166215 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 83.5" "Cell type enriched" "Detected in many" 5 "Platelets: 1010.3" "Cell type enhanced" "Detected in all" "endothelial cell: 81.2;leukocyte: 34.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "basophil: 360.4;eosinophil: 109.4;neutrophil: 430.5" "Lineage enriched" "Detected in all" 8 "granulocytes: 430.5" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 47: Leukemia - Hemostasis" "Cluster 47: Platelets - Hemostasis" 44 "unprognostic (1.03e-3)" "unprognostic (2.37e-1)" "unprognostic (1.24e-1)" "unprognostic (1.03e-1)" "unprognostic (4.42e-1)" "unprognostic (2.82e-2)" "unprognostic (9.75e-2)" "unprognostic (1.30e-3)" "unprognostic (2.18e-2)" "unprognostic (5.77e-3)" "potential prognostic favorable (6.73e-6)" "unprognostic (1.89e-2)" "unprognostic (7.50e-3)" "unprognostic (2.26e-1)" "unprognostic (1.81e-2)" "unprognostic (4.44e-2)" "unprognostic (3.73e-2)" "unprognostic (1.54e-3)" "unprognostic (1.36e-1)" "unprognostic (1.18e-1)" "unprognostic (3.16e-2)" "unprognostic (4.08e-2)" "unprognostic (4.33e-1)" "unprognostic (3.17e-1)" "unprognostic (7.35e-2)" "unprognostic (3.64e-2)" "unprognostic (3.52e-1)" "unprognostic (4.33e-2)" "unprognostic (1.10e-1)" "unprognostic (1.29e-1)" "unprognostic (1.03e-1)" TMEM141 MGC14141 ENSG00000244187 "Transmembrane protein 141" Q96I45 9 136791344-136793317 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 82.4;Enteric stem cells: 37.3;Enteric transient amplifying cells: 44.3;Esophageal apical cells: 42.2;Gastric chief cells: 55.7;Goblet cells: 51.9;Late spermatids: 48.7;Parietal cells: 208.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Prostate - Prostate glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014615, HPA050244" Approved Supported "Cell Junctions,Mitochondria" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 60: Stomach - Digestion" "Cluster 45: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 3 Mitochondria "Cell Junctions" "HPA014615: , HPA050244: " "unprognostic (1.21e-2)" "unprognostic (4.80e-2)" "unprognostic (5.68e-2)" "potential prognostic favorable (3.49e-4)" "unprognostic (1.18e-1)" "unprognostic (1.90e-1)" "unprognostic (2.01e-1)" "unprognostic (9.73e-2)" "potential prognostic unfavorable (3.65e-4)" "unprognostic (1.88e-1)" "unprognostic (2.75e-3)" "unprognostic (3.84e-2)" "unprognostic (5.35e-3)" "unprognostic (3.63e-2)" "potential prognostic unfavorable (9.21e-5)" "unprognostic (5.80e-2)" "unprognostic (2.52e-2)" "unprognostic (1.22e-1)" "unprognostic (4.89e-1)" "unprognostic (4.78e-2)" "unprognostic (3.61e-1)" "unprognostic (6.06e-2)" "unprognostic (3.64e-1)" "unprognostic (5.33e-2)" "unprognostic (1.43e-3)" "unprognostic (7.61e-3)" "unprognostic (6.73e-2)" "unprognostic (1.37e-1)" "unprognostic (3.97e-1)" "unprognostic (3.34e-2)" "unprognostic (2.11e-1)" TMEM143 FLJ10922 ENSG00000161558 "Transmembrane protein 143" Q96AN5 19 48332356-48364059 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 41.6;skeletal muscle: 89.4;tongue: 57.1" "Cell type enhanced" "Detected in many" "Myonuclei: 51.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014476, HPA058645" Approved Approved "Nucleoli fibrillar center" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 37: Neurons - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 14 "Nucleoli fibrillar center" "HPA014476: , HPA058645: " "unprognostic (2.63e-2)" "unprognostic (1.48e-2)" "unprognostic (2.76e-1)" "unprognostic (5.07e-2)" "unprognostic (1.10e-1)" "unprognostic (1.32e-1)" "unprognostic (1.30e-2)" "unprognostic (8.57e-3)" "unprognostic (2.68e-2)" "unprognostic (3.20e-2)" "unprognostic (4.35e-2)" "unprognostic (1.30e-1)" "potential prognostic favorable (2.70e-9)" "unprognostic (9.35e-2)" "unprognostic (9.84e-2)" "unprognostic (4.73e-2)" "unprognostic (5.08e-2)" "unprognostic (2.01e-2)" "unprognostic (5.31e-1)" "unprognostic (1.73e-1)" "unprognostic (2.61e-1)" "unprognostic (1.01e-1)" "unprognostic (2.27e-1)" "unprognostic (4.07e-2)" "unprognostic (7.19e-2)" "unprognostic (3.02e-2)" "unprognostic (3.26e-2)" "unprognostic (1.24e-1)" "unprognostic (8.50e-2)" "unprognostic (2.65e-2)" "unprognostic (3.06e-1)" TMEM144 FLJ11155 ENSG00000164124 "Transmembrane protein 144" Q7Z5S9 4 158201604-158255416 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 218.6" "Cell type enriched" "Detected in many" 5 "Oligodendrocytes: 1569.6" "Cell type enriched" "Detected in all" 4 "oligodendrocyte: 2149.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.1;plasmacytoid DC: 2.2" "Group enriched" "Detected in many" 10 "dendritic cells: 2.2;monocytes: 1.4" "Low cancer specificity" "Detected in many" "Skeletal muscle - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063554 Approved Mitochondria NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 5: Rhabdoid - Unknown function" "Cluster 80: Oligodendrocytes - Myelination" 5 Mitochondria "HPA063554: " "unprognostic (1.99e-1)" "unprognostic (1.67e-1)" "unprognostic (2.75e-1)" "unprognostic (3.25e-3)" "unprognostic (8.61e-2)" "unprognostic (2.11e-1)" "unprognostic (1.83e-1)" "unprognostic (1.18e-2)" "unprognostic (1.28e-3)" "unprognostic (1.76e-2)" "potential prognostic favorable (9.27e-5)" "unprognostic (9.97e-2)" "unprognostic (1.03e-1)" "unprognostic (1.32e-1)" "unprognostic (4.40e-2)" "unprognostic (2.15e-1)" "unprognostic (5.20e-1)" "unprognostic (1.28e-2)" "unprognostic (3.20e-2)" "unprognostic (1.82e-1)" "unprognostic (1.20e-1)" "potential prognostic unfavorable (7.19e-4)" "unprognostic (1.59e-1)" "unprognostic (1.63e-2)" "unprognostic (3.48e-2)" "unprognostic (7.52e-2)" "unprognostic (3.27e-2)" "unprognostic (2.26e-2)" "unprognostic (1.78e-1)" "unprognostic (2.55e-2)" "unprognostic (1.28e-1)" TMEM145 FLJ90805 ENSG00000167619 "Transmembrane protein 145" Q8NBT3 19 42313309-42325064 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 237.2" "Cell type enhanced" "Detected in some" "Astrocytes: 19.4;Bergmann glia: 26.9;Brain excitatory neurons: 47.5;Brain inhibitory neurons: 50.5;Cone photoreceptor cells: 20.7;Differentiating spermatogonia: 24.4;Early primary spermatocytes: 19.6;Oligodendrocyte progenitor cells: 23.9;Other brain neurons: 25.1;Retinal amacrine cells: 81.7;Retinal bipolar cells: 45.1;Retinal ganglion cells: 57.9;Retinal horizontal cells: 52.1;Rod photoreceptor cells: 19.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "basophil: 5.0;neutrophil: 13.6" "Lineage enriched" "Detected in many" 11 "granulocytes: 13.6" "Cancer enhanced" "Detected in many" "Neuroblastoma: 23.6" "Adrenal gland - Adrenal medulla cells, Pancreas - Alpha cells, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060462 Enhanced Approved Approved Vesicles NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 27: Cerebellum - Synaptic function" "Cluster 2: Neurons - Nucleosome" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" Vesicles "HPA060462: " "unprognostic (1.29e-1)" "unprognostic (2.70e-1)" "unprognostic (1.28e-2)" "unprognostic (4.00e-2)" "unprognostic (1.41e-3)" "unprognostic (2.34e-1)" "unprognostic (3.34e-1)" "unprognostic (3.78e-2)" "unprognostic (4.49e-2)" "potential prognostic unfavorable (6.63e-5)" "potential prognostic unfavorable (2.17e-6)" "unprognostic (1.23e-2)" "unprognostic (3.11e-1)" "unprognostic (4.20e-2)" "unprognostic (4.15e-2)" "unprognostic (1.68e-1)" "unprognostic (4.27e-2)" "unprognostic (1.92e-3)" "unprognostic (1.27e-1)" "unprognostic (4.79e-1)" "potential prognostic favorable (9.40e-5)" "unprognostic (1.19e-2)" "unprognostic (3.30e-2)" "unprognostic (3.18e-1)" "unprognostic (7.48e-3)" "unprognostic (3.19e-1)" "unprognostic (4.79e-2)" "unprognostic (6.21e-2)" "unprognostic (1.79e-1)" "unprognostic (8.52e-2)" TMEM147 "MGC1936, NIFIE14" ENSG00000105677 "Transmembrane protein 147" Q9BVK8 19 35545600-35547526 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early primary spermatocytes: 348.0;Esophageal apical cells: 702.6;Esophageal suprabasal cells: 512.8;Late spermatids: 560.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 11000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 4: Non-specific - Transcription" "Cluster 85: Squamous epithelial cells - Keratinization" 65 "unprognostic (5.67e-2)" "unprognostic (2.26e-1)" "unprognostic (2.94e-1)" "unprognostic (3.56e-2)" "unprognostic (8.18e-2)" "unprognostic (1.38e-1)" "unprognostic (2.79e-1)" "unprognostic (1.67e-2)" "unprognostic (7.80e-3)" "unprognostic (4.96e-3)" "unprognostic (5.23e-2)" "unprognostic (3.01e-2)" "unprognostic (1.07e-1)" "potential prognostic unfavorable (3.67e-6)" "unprognostic (3.21e-3)" "unprognostic (2.17e-3)" "unprognostic (4.49e-1)" "unprognostic (1.24e-1)" "unprognostic (2.31e-1)" "unprognostic (1.05e-1)" "unprognostic (1.25e-1)" "unprognostic (1.03e-1)" "unprognostic (1.22e-1)" "unprognostic (8.82e-2)" "unprognostic (1.10e-1)" "unprognostic (2.78e-1)" "unprognostic (1.47e-1)" "unprognostic (2.34e-1)" "unprognostic (2.01e-1)" "unprognostic (4.15e-2)" "unprognostic (2.98e-1)" TMEM14A "C6orf73, PTD011" ENSG00000096092 "Transmembrane protein 14A" Q9Y6G1 6 52671113-52686588 "Predicted membrane proteins, Transporters" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 261.2;Esophageal suprabasal cells: 265.9;Extravillous trophoblasts: 212.0;Gastric progenitor cells: 171.7;Hepatocytes: 166.0;Oocytes: 198.0;Parietal cells: 162.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072536 Approved Approved "Nucleoplasm,Endoplasmic reticulum" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 97: Non-specific - Cellular respiration" 21 "Nucleoplasm, Endoplasmic reticulum" "HPA072536: " "unprognostic (2.61e-1)" "unprognostic (5.97e-3)" "unprognostic (2.44e-1)" "unprognostic (5.90e-2)" "unprognostic (3.58e-1)" "unprognostic (1.35e-1)" "unprognostic (7.16e-2)" "unprognostic (6.08e-1)" "unprognostic (7.66e-2)" "unprognostic (1.38e-2)" "potential prognostic favorable (1.10e-6)" "unprognostic (2.84e-1)" "unprognostic (3.03e-2)" "unprognostic (5.86e-2)" "unprognostic (3.93e-3)" "unprognostic (2.11e-2)" "unprognostic (2.27e-1)" "unprognostic (1.02e-3)" "unprognostic (3.87e-2)" "unprognostic (4.49e-2)" "unprognostic (1.82e-3)" "unprognostic (1.36e-1)" "unprognostic (2.99e-1)" "unprognostic (2.05e-1)" "unprognostic (1.60e-1)" "unprognostic (2.64e-2)" "unprognostic (4.84e-2)" "unprognostic (4.24e-1)" "unprognostic (7.84e-2)" "unprognostic (2.69e-2)" "unprognostic (1.45e-1)" TMEM14B MGC1223 ENSG00000137210 "Transmembrane protein 14B" Q9NUH8 6 10747759-10852753 "Predicted membrane proteins, Transporters" Neurogenesis "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 161.8;Fallopian tube ciliated cells: 105.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Thyroid gland - Thyroid glandular cells" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 195 "unprognostic (2.75e-1)" "unprognostic (2.86e-2)" "unprognostic (1.59e-1)" "unprognostic (8.64e-2)" "unprognostic (3.19e-1)" "unprognostic (2.82e-1)" "unprognostic (1.21e-1)" "unprognostic (1.25e-1)" "unprognostic (8.62e-3)" "unprognostic (1.26e-2)" "potential prognostic favorable (5.56e-4)" "unprognostic (1.74e-2)" "unprognostic (3.26e-3)" "potential prognostic unfavorable (3.91e-4)" "unprognostic (1.08e-2)" "unprognostic (3.18e-2)" "unprognostic (2.52e-2)" "unprognostic (7.24e-2)" "unprognostic (4.37e-2)" "potential prognostic favorable (1.28e-5)" "unprognostic (2.60e-1)" "unprognostic (1.14e-1)" "unprognostic (2.24e-2)" "unprognostic (3.70e-2)" "unprognostic (6.38e-2)" "unprognostic (2.73e-2)" "unprognostic (5.33e-3)" "unprognostic (1.08e-1)" "unprognostic (2.35e-1)" "unprognostic (1.38e-1)" "unprognostic (2.04e-1)" TMEM14C "bA421M1.6, C6orf53, HSPC194, NET26" ENSG00000111843 "Transmembrane protein 14C" Q9P0S9 6 10722915-10731129 "Predicted membrane proteins, Transporters" "Heme biosynthesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 110.1;Megakaryocyte-Erythroid progenitors: 73.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 20000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 74: Non-specific - Signal transduction" "Cluster 21: Non-specific - Metabolism" "Cluster 28: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 35 "unprognostic (2.65e-2)" "unprognostic (7.02e-2)" "unprognostic (4.19e-2)" "unprognostic (3.50e-2)" "unprognostic (1.57e-1)" "unprognostic (1.76e-1)" "unprognostic (5.19e-2)" "unprognostic (6.51e-2)" "unprognostic (5.24e-2)" "unprognostic (2.16e-1)" "validated prognostic favorable (1.39e-6)" "validated prognostic favorable (7.76e-4)" "unprognostic (7.69e-2)" "validated prognostic unfavorable (7.54e-4)" "validated prognostic unfavorable (1.93e-4)" "unprognostic (1.46e-1)" "unprognostic (2.42e-2)" "unprognostic (3.30e-1)" "unprognostic (2.93e-2)" "unprognostic (5.30e-2)" "unprognostic (1.27e-1)" "unprognostic (4.16e-2)" "unprognostic (1.20e-1)" "unprognostic (3.66e-1)" "unprognostic (2.73e-2)" "unprognostic (5.10e-2)" "unprognostic (4.01e-2)" "unprognostic (4.05e-2)" "unprognostic (5.69e-2)" "unprognostic (1.84e-1)" "unprognostic (9.10e-2)" TMEM150A "FLJ90024, TM6P1, TMEM150, TTN1" ENSG00000168890 "Transmembrane protein 150A" Q86TG1 2 85598547-85603196 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 173.2;Early spermatids: 192.1;Late spermatids: 90.2;Migrating cytotrophoblasts: 61.4;Syncytiotrophoblasts: 151.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019015 Uncertain NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 44: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 4 "HPA019015: " "unprognostic (2.24e-1)" "unprognostic (3.21e-2)" "unprognostic (2.82e-2)" "unprognostic (4.94e-2)" "unprognostic (3.98e-2)" "unprognostic (2.32e-1)" "validated prognostic unfavorable (5.67e-4)" "validated prognostic unfavorable (1.38e-4)" "unprognostic (4.63e-3)" "unprognostic (7.78e-2)" "potential prognostic favorable (7.96e-4)" "unprognostic (5.17e-2)" "unprognostic (1.16e-2)" "unprognostic (1.62e-2)" "unprognostic (4.13e-1)" "unprognostic (6.83e-3)" "unprognostic (1.60e-1)" "unprognostic (9.11e-2)" "unprognostic (3.44e-2)" "unprognostic (5.59e-2)" "unprognostic (7.18e-3)" "unprognostic (1.88e-1)" "unprognostic (1.32e-3)" "unprognostic (3.20e-1)" "unprognostic (9.66e-2)" "unprognostic (2.55e-1)" "unprognostic (1.70e-1)" "unprognostic (4.08e-2)" "unprognostic (7.98e-2)" "unprognostic (4.93e-2)" "unprognostic (9.42e-2)" TMEM150B "DRAM3, TMEM224, TTN2" ENSG00000180061 "Transmembrane protein 150B" A6NC51 19 55312801-55334048 "Predicted membrane proteins, Transporters" Autophagy "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 5 "intestine: 60.2" "Cell type enhanced" "Detected in some" "Colonocytes: 17.1;Enterocytes: 106.7;Goblet cells: 13.0;Hofbauer cells: 12.1;Kupffer cells: 19.5;Macrophages: 11.9;monocytes: 16.5;Paneth cells: 11.6;Proximal tubule cells: 28.3" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 2.0" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 24.7;Rectum Adenocarcinoma (TCGA): 23.4" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "classical monocyte: 5.7" "Group enriched" "Detected in many" 7 "granulocytes: 1.9;monocytes: 5.7" "Cancer enhanced" "Detected in some" "colorectal cancer: 9.3;Gastric cancer: 4.3" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Proximal tubular cells, Lung - Macrophages, Minor Salivary Gland - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Spleen - Macrophages, Stomach - Macrophages, Thyroid gland - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 12: Non-specific - Vasculature" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 1: Enterocytes - Absorption and Digestion" "unprognostic (3.03e-2)" "unprognostic (2.56e-1)" "unprognostic (3.05e-1)" "unprognostic (9.89e-2)" "unprognostic (1.50e-1)" "unprognostic (7.51e-2)" "unprognostic (8.28e-2)" "unprognostic (1.52e-2)" "unprognostic (1.28e-1)" "unprognostic (1.56e-2)" "unprognostic (3.01e-1)" "unprognostic (3.40e-1)" "unprognostic (3.85e-2)" "unprognostic (1.76e-1)" "unprognostic (1.53e-1)" "unprognostic (1.88e-1)" "unprognostic (2.99e-1)" "unprognostic (7.19e-2)" "unprognostic (3.40e-1)" "unprognostic (1.12e-2)" "unprognostic (2.41e-1)" "unprognostic (3.52e-2)" "unprognostic (3.60e-1)" "unprognostic (6.93e-2)" "unprognostic (5.98e-2)" "potential prognostic unfavorable (6.55e-4)" TMEM150C "FLJ12993, TTN3" ENSG00000249242 "Transmembrane protein 150C" B9EJG8 4 82483170-82562357 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 127.4" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 135.7;Cytotrophoblasts: 190.1;Epididymal principal cells: 223.3;Podocytes: 288.8;Somatotrophs: 155.2;Syncytiotrophoblasts: 205.2;Thyrotrophs: 121.5" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Breast Invasive Carcinoma (TCGA): 42.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.2" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "prostate cancer: 12.3" "Adrenal gland - Adrenal cortex cells, Colon - Colon enteroendocrine cells, Kidney - Podocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052921 Enhanced NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 14: Neurons - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" "HPA052921: " "unprognostic (6.05e-2)" "unprognostic (1.82e-1)" "unprognostic (3.25e-2)" "unprognostic (2.11e-1)" "unprognostic (8.54e-2)" "unprognostic (2.14e-1)" "unprognostic (1.82e-3)" "unprognostic (1.17e-2)" "unprognostic (4.12e-3)" "unprognostic (1.46e-2)" "validated prognostic favorable (3.94e-12)" "validated prognostic favorable (1.41e-6)" "unprognostic (2.58e-3)" "unprognostic (6.43e-2)" "unprognostic (2.99e-2)" "unprognostic (6.04e-2)" "unprognostic (5.35e-2)" "unprognostic (1.62e-1)" "unprognostic (2.00e-1)" "unprognostic (3.18e-1)" "unprognostic (2.73e-2)" "potential prognostic favorable (4.37e-4)" "unprognostic (1.54e-1)" "unprognostic (2.59e-2)" "unprognostic (7.63e-2)" "unprognostic (7.66e-2)" "unprognostic (2.10e-1)" "unprognostic (2.23e-1)" "unprognostic (4.77e-2)" "unprognostic (2.27e-1)" "unprognostic (8.71e-2)" TMEM151A "MGC33486, TMEM151" ENSG00000179292 "Transmembrane protein 151A" Q8N4L1 11 66291894-66296664 "Predicted membrane proteins" "Disease variant, Dystonia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "brain: 133.9" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 16.3;Brain inhibitory neurons: 19.6;Mesothelial cells: 9.2;Oligodendrocytes: 88.8;Other brain neurons: 23.1;Pancreatic islet cells: 7.5;Retinal amacrine cells: 7.6;Retinal horizontal cells: 8.0;Retinal pigment epithelial cells: 17.1" "Cell type enhanced" "Detected in all" "oligodendrocyte: 116.8" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 7.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041035 Uncertain Approved Nucleoli,Cytosol NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 72: Neuronal - Signal transduction" "Cluster 80: Oligodendrocytes - Myelination" 1 Nucleoli Cytosol "HPA041035: " "unprognostic (2.66e-1)" "unprognostic (2.86e-1)" "unprognostic (1.31e-1)" "unprognostic (1.55e-1)" "unprognostic (8.33e-3)" "unprognostic (1.45e-2)" "unprognostic (2.99e-2)" "unprognostic (6.65e-2)" TMEM151B "bA444E17.5, C6orf137, TMEM193" ENSG00000178233 "Transmembrane protein 151B" Q8IW70 6 44270450-44307506 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 37 "brain: 135.4" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 3.5;Brain inhibitory neurons: 1.5;Other brain neurons: 1.1" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 9 "Neuroblastoma: 26.5" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055167 Uncertain NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 15: Non-specific - Transcription" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 2: Cerebellar granular cells - Neuronal signaling" "HPA055167: " "unprognostic (1.08e-1)" "unprognostic (6.03e-2)" "unprognostic (4.62e-3)" "unprognostic (2.36e-2)" "unprognostic (8.59e-2)" "unprognostic (8.98e-2)" TMEM154 FLJ32028 ENSG00000170006 "Transmembrane protein 154" Q6P9G4 4 152618628-152680012 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 19.1;skin 1: 45.7" "Cell type enhanced" "Detected in many" "B-cells: 223.3;Esophageal apical cells: 1271.4;Esophageal suprabasal cells: 487.8;Mast cells: 206.6;Neutrophil progenitors: 394.9;Neutrophils: 1233.5;Suprabasal keratinocytes: 560.0;Urothelial cells: 264.9" "Group enriched" "Detected in some" 8 "central nervous system macrophage: 72.7;endothelial cell: 34.7;leukocyte: 52.9" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 20.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 36.8;eosinophil: 20.8;neutrophil: 35.9" "Lineage enriched" "Detected in many" 6 "granulocytes: 36.8" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (other)" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA019184, HPA055411" Uncertain Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 58: Skin - Keratinization" "Cluster 6: Non-specific - Immune response" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 17 "Nuclear membrane" Nucleoplasm "HPA019184: , HPA055411: " "unprognostic (1.34e-1)" "unprognostic (8.36e-2)" "unprognostic (7.00e-2)" "unprognostic (3.45e-2)" "unprognostic (3.71e-2)" "unprognostic (7.32e-2)" "unprognostic (1.95e-1)" "unprognostic (3.12e-3)" "unprognostic (2.67e-1)" "unprognostic (9.19e-2)" "unprognostic (1.26e-1)" "unprognostic (3.60e-2)" "potential prognostic favorable (2.06e-4)" "unprognostic (1.88e-1)" "unprognostic (1.07e-1)" "unprognostic (2.46e-1)" "unprognostic (1.53e-1)" "potential prognostic unfavorable (9.70e-4)" "unprognostic (5.03e-2)" "unprognostic (2.87e-1)" "unprognostic (1.24e-1)" "unprognostic (4.56e-2)" "unprognostic (2.21e-1)" "unprognostic (4.16e-2)" "unprognostic (2.03e-2)" "unprognostic (3.99e-2)" TMEM156 FLJ23235 ENSG00000121895 "Transmembrane protein 156" Q8N614 4 38966744-39032922 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 25.1" "Cell type enhanced" "Detected in many" "B-cells: 337.0;cDC: 61.4;Innate lymphoid cells: 140.2;Kupffer cells: 93.3;Megakaryocyte-Erythroid progenitors: 52.6;Microglia: 394.1;NK-cells: 93.5;Plasma cells: 271.0;T-cells: 91.7;Thymocytes: 100.8" "Cell type enriched" "Detected in many" 5 "central nervous system macrophage: 475.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 75.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Heart muscle - T-cells, Minor Salivary Gland - Plasma cells, Prostate - T-cells, Spleen - B-cells (Spleen)" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 25: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 87: B-cells - Adaptive immunity: Humoral response" "unprognostic (4.61e-2)" "unprognostic (1.87e-2)" "unprognostic (1.68e-1)" "unprognostic (7.03e-2)" "unprognostic (2.14e-1)" "unprognostic (2.80e-1)" "unprognostic (3.11e-1)" "unprognostic (1.30e-2)" "potential prognostic favorable (7.31e-4)" "unprognostic (2.68e-1)" "unprognostic (7.82e-2)" "unprognostic (1.29e-1)" "unprognostic (1.67e-1)" "unprognostic (1.45e-1)" "unprognostic (5.07e-2)" "unprognostic (2.53e-3)" "unprognostic (1.05e-1)" "unprognostic (2.14e-1)" "unprognostic (5.75e-2)" "unprognostic (2.07e-2)" "potential prognostic unfavorable (1.10e-4)" "unprognostic (5.38e-2)" "unprognostic (3.17e-1)" "unprognostic (1.67e-1)" "potential prognostic favorable (8.65e-4)" "unprognostic (4.28e-2)" TMEM158 "p40BBp, RIS1" ENSG00000249992 "Transmembrane protein 158" Q8WZ71 3 45224466-45226287 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 82.8;endometrium 1: 60.4" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 45.6;Breast myoepithelial cells: 43.9;Endometrial stromal cells: 47.3;Ependymal cells: 57.8;Fibroblasts: 34.2;Müller glia: 94.0;Other brain neurons: 59.1;Platelets: 227.9" "Cell type enhanced" "Detected in all" "medium spiny neuron: 106.9" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 64.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 58.8" "Pancreas - Ductal cells, Pituitary gland - Lactotropes, Prostate - Smooth muscle cells" "Region enhanced" "Detected in all" "basal ganglia: 95.5" "Low region specificity" "Detected in all" HPA074974 Approved NA NA "Cluster 65: Brain - Transcription" "Cluster 33: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 17: Non-specific - RNA processing" "HPA074974: " "unprognostic (2.66e-1)" "unprognostic (3.85e-1)" "unprognostic (8.77e-2)" "unprognostic (1.05e-1)" "unprognostic (1.95e-1)" "unprognostic (1.10e-1)" "unprognostic (7.99e-2)" "unprognostic (9.90e-3)" "unprognostic (3.48e-2)" "unprognostic (1.13e-2)" "potential prognostic unfavorable (5.69e-7)" "unprognostic (8.94e-2)" "potential prognostic unfavorable (4.13e-4)" "unprognostic (6.47e-2)" "unprognostic (4.20e-3)" "unprognostic (2.86e-3)" "unprognostic (7.18e-2)" "unprognostic (8.54e-2)" "unprognostic (2.55e-2)" "unprognostic (2.03e-3)" "unprognostic (2.07e-3)" "unprognostic (3.57e-2)" "potential prognostic favorable (9.30e-4)" "unprognostic (4.62e-1)" "unprognostic (1.14e-2)" "unprognostic (7.91e-2)" "unprognostic (9.37e-2)" "unprognostic (5.13e-1)" "unprognostic (1.66e-1)" TMEM160 FLJ20512 ENSG00000130748 "Transmembrane protein 160" Q9NX00 19 47045909-47048624 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 99.9" "Cell type enhanced" "Detected in many" "Late spermatids: 433.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055904 Uncertain NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 30 "HPA055904: " "unprognostic (3.07e-1)" "unprognostic (1.24e-2)" "unprognostic (4.32e-1)" "unprognostic (1.83e-1)" "unprognostic (3.15e-1)" "unprognostic (1.61e-1)" "unprognostic (1.99e-1)" "unprognostic (2.76e-1)" "unprognostic (1.33e-1)" "unprognostic (1.88e-1)" "unprognostic (3.38e-2)" "unprognostic (7.50e-2)" "unprognostic (1.94e-1)" "unprognostic (7.63e-2)" "unprognostic (2.41e-2)" "unprognostic (9.68e-2)" "unprognostic (1.41e-1)" "unprognostic (2.14e-2)" "unprognostic (1.69e-1)" "unprognostic (2.28e-1)" "unprognostic (3.20e-2)" "unprognostic (1.00e-2)" "unprognostic (1.38e-2)" "unprognostic (5.14e-2)" "unprognostic (2.03e-1)" "unprognostic (2.42e-1)" "unprognostic (1.32e-1)" "unprognostic (1.68e-1)" "unprognostic (1.40e-1)" "unprognostic (8.15e-2)" "unprognostic (6.83e-2)" TMEM161A "FLJ20422, FLJ39645" ENSG00000064545 "Transmembrane protein 161A" Q9NX61 19 19119169-19138513 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 59.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043365 Approved Approved Cytosol NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 24: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 22 Cytosol "HPA043365: " "unprognostic (2.76e-1)" "unprognostic (2.40e-3)" "unprognostic (3.88e-2)" "unprognostic (8.99e-2)" "unprognostic (1.79e-2)" "unprognostic (5.16e-2)" "unprognostic (1.81e-1)" "unprognostic (9.80e-2)" "unprognostic (3.23e-1)" "potential prognostic unfavorable (2.03e-4)" "potential prognostic favorable (3.67e-5)" "unprognostic (1.90e-1)" "unprognostic (3.59e-2)" "unprognostic (8.59e-3)" "unprognostic (1.11e-1)" "unprognostic (2.59e-2)" "unprognostic (2.44e-1)" "unprognostic (6.52e-2)" "unprognostic (1.75e-2)" "unprognostic (1.62e-1)" "unprognostic (1.34e-1)" "unprognostic (3.56e-1)" "unprognostic (3.96e-1)" "unprognostic (6.33e-2)" "unprognostic (1.31e-2)" "unprognostic (2.16e-3)" "unprognostic (3.10e-1)" "unprognostic (2.61e-3)" "unprognostic (1.50e-1)" "unprognostic (3.35e-1)" "unprognostic (5.63e-2)" TMEM161B MGC33214 ENSG00000164180 "Transmembrane protein 161B" Q8NDZ6 5 88189633-88269476 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Parietal cells: 203.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044562 Uncertain NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 9: Non-specific - Receptor signaling" "Cluster 47: Leukemia - Hemostasis" "Cluster 97: Non-specific - Cellular respiration" 2 "HPA044562: " "unprognostic (5.49e-2)" "unprognostic (1.01e-1)" "unprognostic (2.51e-1)" "unprognostic (6.09e-2)" "unprognostic (1.22e-1)" "unprognostic (7.14e-2)" "unprognostic (1.65e-1)" "unprognostic (4.42e-2)" "unprognostic (3.16e-1)" "potential prognostic unfavorable (4.85e-4)" "potential prognostic favorable (2.54e-5)" "unprognostic (4.09e-2)" "unprognostic (1.27e-1)" "unprognostic (1.45e-3)" "unprognostic (6.26e-2)" "unprognostic (1.51e-1)" "unprognostic (3.19e-1)" "unprognostic (1.04e-1)" "unprognostic (2.82e-1)" "unprognostic (1.79e-2)" "unprognostic (5.79e-2)" "unprognostic (6.58e-2)" "unprognostic (1.68e-2)" "unprognostic (4.92e-2)" "potential prognostic favorable (7.84e-4)" "unprognostic (1.99e-1)" "unprognostic (2.98e-1)" "unprognostic (1.96e-1)" "unprognostic (2.86e-2)" "unprognostic (1.30e-1)" "unprognostic (3.07e-1)" TMEM163 "DKFZP566N034, SV31" ENSG00000152128 "Transmembrane protein 163" Q8TC26 2 134455759-134719000 "Predicted membrane proteins, Transporters" Transport "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 44.4;pancreas: 26.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 950.2;Ependymal cells: 295.8;Foveolar cells: 352.9;Gonadotrophs: 536.0;Hematopoietic stem cells: 269.3;Lactotrophs: 285.0;Oligodendrocyte progenitor cells: 343.7;Oocytes: 363.8;Pancreatic acinar cells: 1089.1;Pancreatic islet cells: 346.2;Pituitary stem cells: 319.3;Retinal ganglion cells: 536.9;Sertoli cells: 305.0;Somatotrophs: 345.1" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 706.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 16.3" "Lung - Alveolar cells type 2, Skin - Outer root sheath cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007224 Uncertain NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 4 "HPA007224: " "unprognostic (9.00e-3)" "unprognostic (4.22e-2)" "unprognostic (1.04e-2)" "unprognostic (9.64e-2)" "unprognostic (1.08e-1)" "unprognostic (1.77e-1)" "unprognostic (3.51e-2)" "unprognostic (1.74e-1)" "unprognostic (4.40e-2)" "unprognostic (1.97e-2)" "unprognostic (3.16e-2)" "potential prognostic favorable (9.64e-4)" "unprognostic (8.36e-3)" "unprognostic (8.90e-2)" "validated prognostic favorable (3.34e-4)" "validated prognostic favorable (3.62e-4)" "unprognostic (3.63e-1)" "unprognostic (4.23e-1)" "unprognostic (2.09e-2)" "unprognostic (1.24e-2)" "unprognostic (1.00e-1)" "unprognostic (3.30e-2)" "unprognostic (1.54e-2)" "unprognostic (3.57e-1)" "unprognostic (2.19e-2)" "unprognostic (3.38e-1)" "unprognostic (7.53e-2)" "unprognostic (5.82e-3)" "unprognostic (3.91e-2)" TMEM164 "FLJ22679, RP13-360B22.2" ENSG00000157600 "Transmembrane protein 164" Q5U3C3 X 110002631-110182734 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 461.3;Alveolar cells type 2: 309.5;Cardiomyocytes: 437.4;Choroid plexus epithelial cells: 310.0;Myonuclei: 338.8;Neutrophils: 288.3;Pituicytes/FSCs: 405.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 59.8" "Lineage enriched" "Detected in many" 18 "granulocytes: 59.8" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038784 Approved Approved "Vesicles,Cell Junctions" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 38: Sub-cortical - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 89: Adipocytes - Lipid metabolism" Vesicles "Cell Junctions" "HPA038784: " "unprognostic (3.01e-1)" "unprognostic (2.26e-2)" "unprognostic (8.14e-2)" "unprognostic (5.65e-2)" "unprognostic (3.44e-2)" "unprognostic (7.24e-2)" "unprognostic (4.00e-2)" "unprognostic (2.01e-2)" "unprognostic (1.28e-2)" "unprognostic (5.65e-2)" "unprognostic (2.72e-2)" "unprognostic (2.04e-1)" "unprognostic (2.09e-2)" "validated prognostic unfavorable (9.08e-5)" "validated prognostic unfavorable (8.10e-4)" "unprognostic (6.20e-3)" "unprognostic (7.36e-2)" "unprognostic (1.15e-1)" "unprognostic (3.16e-2)" "unprognostic (1.61e-1)" "unprognostic (1.31e-1)" "unprognostic (5.14e-2)" "unprognostic (2.06e-1)" "unprognostic (2.29e-1)" "unprognostic (4.19e-2)" "unprognostic (2.42e-1)" "unprognostic (1.44e-1)" "potential prognostic favorable (7.86e-4)" "unprognostic (1.63e-1)" "unprognostic (1.40e-3)" "unprognostic (1.92e-1)" TMEM165 "GDT1, SLC64A1, TMPT27, TPARL" ENSG00000134851 "Transmembrane protein 165" Q9HC07 4 55395957-55453397 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Transport" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 921.2;Oligodendrocytes: 1125.2" "Cell type enriched" "Detected in all" 4 "oligodendrocyte: 1598.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038299, HPA062424" Supported Enhanced "Golgi apparatus" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 9 "Golgi apparatus" "HPA038299: , HPA062424: " "unprognostic (7.95e-3)" "unprognostic (1.56e-3)" "unprognostic (7.01e-2)" "potential prognostic unfavorable (2.96e-5)" "potential prognostic favorable (9.94e-4)" "unprognostic (7.24e-3)" "unprognostic (1.87e-2)" "unprognostic (2.54e-2)" "unprognostic (5.69e-2)" "unprognostic (2.58e-2)" "unprognostic (8.73e-3)" "unprognostic (2.78e-1)" "unprognostic (2.14e-1)" "potential prognostic unfavorable (1.25e-5)" "unprognostic (1.39e-2)" "unprognostic (1.42e-2)" "unprognostic (6.98e-3)" "unprognostic (2.89e-1)" "unprognostic (2.86e-1)" "unprognostic (1.62e-1)" "unprognostic (2.36e-1)" "unprognostic (3.88e-2)" "unprognostic (1.27e-1)" "unprognostic (2.96e-1)" "unprognostic (8.45e-2)" "unprognostic (3.13e-2)" "unprognostic (1.27e-2)" "unprognostic (2.12e-2)" "unprognostic (3.00e-1)" "unprognostic (1.48e-1)" "unprognostic (1.75e-2)" TMEM167A "FLJ30508, MGC23909, TMEM167" ENSG00000174695 "Transmembrane protein 167A" Q8TBQ9 5 83052846-83077863 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 351.6;Extravillous trophoblasts: 429.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077278 Approved Vesicles NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 76: Non-specific - Metabolism" "Cluster 45: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 8: Non-specific - Secretory pathway" 1 Vesicles "HPA077278: " "unprognostic (6.67e-3)" "unprognostic (1.95e-3)" "unprognostic (1.26e-1)" "unprognostic (1.16e-3)" "unprognostic (5.51e-2)" "unprognostic (1.91e-1)" "unprognostic (2.26e-1)" "unprognostic (3.72e-2)" "unprognostic (2.67e-1)" "unprognostic (6.84e-3)" "potential prognostic favorable (5.21e-4)" "unprognostic (3.26e-1)" "unprognostic (3.88e-1)" "unprognostic (2.22e-3)" "unprognostic (2.82e-2)" "unprognostic (1.22e-1)" "unprognostic (1.33e-3)" "unprognostic (3.04e-1)" "unprognostic (1.36e-1)" "unprognostic (1.51e-1)" "potential prognostic unfavorable (2.51e-5)" "unprognostic (2.27e-1)" "potential prognostic unfavorable (1.37e-4)" "unprognostic (2.18e-1)" "unprognostic (1.61e-1)" "unprognostic (2.11e-1)" "unprognostic (1.72e-2)" "unprognostic (1.76e-2)" "unprognostic (4.33e-1)" "unprognostic (6.77e-3)" "unprognostic (1.17e-1)" TMEM167B "AD-020, C1orf119, FLJ90710" ENSG00000215717 "Transmembrane protein 167B" Q9NRX6 1 109090764-109096934 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 130.2;Neutrophils: 133.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 37: Non-specific - mRNA processing" "Cluster 8: Non-specific - Secretory pathway" 28 "potential prognostic favorable (5.04e-4)" "unprognostic (2.31e-1)" "unprognostic (2.30e-1)" "unprognostic (3.23e-1)" "unprognostic (8.64e-2)" "unprognostic (3.92e-2)" "unprognostic (2.99e-1)" "unprognostic (1.85e-1)" "unprognostic (1.45e-1)" "unprognostic (4.92e-2)" "potential prognostic favorable (2.06e-7)" "unprognostic (1.49e-3)" "unprognostic (2.60e-2)" "potential prognostic unfavorable (9.94e-5)" "unprognostic (1.13e-1)" "unprognostic (1.35e-1)" "unprognostic (7.78e-2)" "unprognostic (3.78e-1)" "unprognostic (2.95e-1)" "unprognostic (1.78e-1)" "unprognostic (2.57e-2)" "unprognostic (1.02e-1)" "unprognostic (1.29e-1)" "unprognostic (4.99e-2)" "unprognostic (7.72e-2)" "unprognostic (4.93e-2)" "unprognostic (2.77e-1)" "unprognostic (1.39e-1)" "unprognostic (1.29e-1)" "unprognostic (1.48e-2)" "unprognostic (2.60e-1)" TMEM168 DKFZp564C012,FLJ13576 ENSG00000146802 "Transmembrane protein 168" Q9H0V1 7 112762377-112790423 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020389, HPA077143" Approved Approved "Golgi apparatus,Cytosol" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 30: White matter - Myelination" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 7: Non-specific - Transcription" 2 "Golgi apparatus" Cytosol "HPA020389: , HPA077143: " "unprognostic (7.33e-2)" "unprognostic (1.70e-1)" "unprognostic (1.42e-1)" "unprognostic (1.41e-2)" "unprognostic (4.68e-2)" "unprognostic (2.10e-2)" "unprognostic (1.81e-1)" "unprognostic (5.84e-2)" "unprognostic (3.21e-2)" "unprognostic (2.67e-3)" "potential prognostic favorable (4.88e-7)" "unprognostic (4.73e-2)" "unprognostic (2.98e-1)" "unprognostic (9.33e-3)" "unprognostic (5.81e-2)" "unprognostic (1.50e-2)" "unprognostic (1.74e-1)" "unprognostic (4.34e-2)" "unprognostic (1.97e-2)" "unprognostic (4.15e-2)" "unprognostic (2.69e-1)" "unprognostic (2.61e-2)" "unprognostic (2.51e-1)" "unprognostic (1.37e-1)" "unprognostic (8.52e-2)" "unprognostic (6.03e-2)" "unprognostic (9.54e-3)" "unprognostic (4.93e-2)" "unprognostic (3.01e-1)" "unprognostic (3.99e-2)" "unprognostic (1.82e-1)" TMEM169 FLJ34263 ENSG00000163449 "Transmembrane protein 169" Q96HH4 2 216081866-216102783 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.9;retina: 3.2" "Cell type enhanced" "Detected in many" "Adipocytes: 13.1;Brain excitatory neurons: 17.3;Brain inhibitory neurons: 13.2;Cone photoreceptor cells: 33.1;Loop of henle epithelial cells: 16.2;Microglia: 16.7;Myosatellite cells: 17.4;Neutrophils: 14.1;Oligodendrocyte progenitor cells: 23.7;Oligodendrocytes: 16.2;Other brain neurons: 17.2;Renal collecting duct principal cells: 25.1;Retinal bipolar cells: 22.8;Retinal ganglion cells: 19.3;Rod photoreceptor cells: 13.8;Thyrotrophs: 14.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 6.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in many" 5 "Neuroblastoma: 19.5" "Adipose subcutaneous - Adipocytes (Subcutaneous), Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA070657, HPA074877" Enhanced Approved "Focal adhesion sites" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "Focal adhesion sites" "HPA070657: , HPA074877: " "unprognostic (2.41e-1)" "unprognostic (4.22e-2)" "unprognostic (7.38e-3)" "unprognostic (1.03e-3)" "unprognostic (1.94e-1)" "unprognostic (1.06e-1)" "unprognostic (4.56e-2)" "unprognostic (1.60e-1)" "unprognostic (2.31e-1)" "unprognostic (1.36e-1)" "unprognostic (5.75e-2)" "unprognostic (8.43e-2)" "unprognostic (7.35e-2)" "unprognostic (1.77e-1)" "unprognostic (9.96e-2)" "unprognostic (1.43e-1)" "unprognostic (1.10e-1)" "unprognostic (8.21e-2)" TMEM17 FLJ34583 ENSG00000186889 "Transmembrane protein 17" Q86X19 2 62500218-62511894 "Predicted membrane proteins, Transporters" "Cilium biogenesis/degradation" Ciliopathy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 21.5;Early primary spermatocytes: 39.8;Epididymal efferent duct ciliated cells: 23.9;Fallopian tube ciliated cells: 23.3;Other brain neurons: 22.2;Platelets: 22.6;Respiratory ciliated cells: 22.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.9" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018100 Uncertain Approved "Golgi apparatus,Actin filaments" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 69: Skin cancer - ECM organization" "Cluster 98: Neurons - Neurotransmission & signaling" 6 "Actin filaments" "Golgi apparatus" "HPA018100: " "unprognostic (2.35e-1)" "unprognostic (5.42e-3)" "unprognostic (1.16e-1)" "unprognostic (4.10e-2)" "unprognostic (2.35e-1)" "unprognostic (1.95e-2)" "potential prognostic unfavorable (9.77e-4)" "unprognostic (1.96e-2)" "unprognostic (2.93e-1)" "unprognostic (2.68e-2)" "potential prognostic favorable (7.41e-4)" "unprognostic (2.88e-3)" "unprognostic (2.40e-2)" "potential prognostic unfavorable (2.94e-5)" "unprognostic (5.37e-3)" "unprognostic (9.29e-2)" "unprognostic (9.23e-2)" "unprognostic (1.45e-1)" "unprognostic (4.91e-2)" "unprognostic (2.19e-2)" "unprognostic (4.13e-1)" "unprognostic (2.01e-1)" "unprognostic (4.71e-3)" "unprognostic (5.30e-2)" "unprognostic (9.30e-2)" "unprognostic (3.29e-2)" "unprognostic (1.36e-1)" "unprognostic (2.11e-2)" "unprognostic (3.83e-2)" "unprognostic (2.05e-2)" "unprognostic (6.84e-2)" TMEM170A "FLJ37611, TMEM170" ENSG00000166822 "Transmembrane protein 170A" Q8WVE7 16 75443054-75465497 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 34.1" "Group enriched" "Detected in some" 4 "Early spermatids: 9.4;Late primary spermatocytes: 18.5" "Cell type enhanced" "Detected in single" "Bergmann glia: 1.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Urothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" "unprognostic (3.23e-1)" "unprognostic (1.37e-2)" "unprognostic (2.61e-1)" "potential prognostic unfavorable (4.95e-5)" "unprognostic (1.72e-1)" "unprognostic (9.22e-2)" "unprognostic (7.78e-2)" "unprognostic (1.95e-1)" "unprognostic (1.21e-1)" "unprognostic (7.63e-2)" "potential prognostic favorable (3.70e-6)" "unprognostic (2.20e-2)" "unprognostic (2.08e-2)" "unprognostic (3.53e-2)" "unprognostic (2.11e-2)" "unprognostic (1.97e-1)" "unprognostic (1.19e-1)" "unprognostic (5.37e-3)" "unprognostic (2.60e-1)" "unprognostic (1.37e-1)" "unprognostic (9.94e-2)" "unprognostic (1.12e-2)" "unprognostic (5.18e-2)" "unprognostic (2.58e-1)" "unprognostic (4.94e-3)" "unprognostic (7.86e-3)" "unprognostic (9.98e-2)" "unprognostic (1.09e-1)" "unprognostic (2.26e-1)" "unprognostic (1.88e-2)" "unprognostic (2.01e-2)" TMEM170B ENSG00000205269 "Transmembrane protein 170B" Q5T4T1 6 11537749-11583524 "Predicted membrane proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 23.8" "Cell type enhanced" "Detected in many" "Monocyte progenitors: 176.1;monocytes: 173.4;Neutrophil progenitors: 274.8;Neutrophils: 173.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 11.5" "Breast - Adipocytes (Breast), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055134 Uncertain Approved Centrosome NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" Centrosome "HPA055134: " "unprognostic (2.07e-1)" "unprognostic (6.78e-2)" "unprognostic (2.55e-2)" "unprognostic (3.00e-2)" "unprognostic (5.33e-2)" "potential prognostic favorable (1.17e-4)" "unprognostic (9.29e-2)" "unprognostic (1.29e-1)" "unprognostic (1.78e-1)" "unprognostic (3.54e-1)" "unprognostic (2.73e-3)" "unprognostic (3.45e-2)" "unprognostic (1.18e-1)" "unprognostic (1.02e-3)" "unprognostic (4.67e-2)" "unprognostic (2.19e-2)" "potential prognostic favorable (3.78e-5)" "unprognostic (9.04e-2)" "unprognostic (2.47e-1)" "unprognostic (2.82e-1)" "unprognostic (1.78e-2)" "unprognostic (1.48e-1)" "unprognostic (1.18e-2)" "unprognostic (1.32e-1)" "unprognostic (2.71e-3)" "unprognostic (2.22e-1)" TMEM171 PRP2 ENSG00000157111 "Transmembrane protein 171" Q8WVE6 5 73120569-73131809 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 33.4;kidney: 10.5;lymphoid tissue: 13.5;stomach 1: 26.1;thyroid gland: 29.2" "Cell type enhanced" "Detected in many" "Breast lactating cells: 103.1;Cholangiocytes: 37.5;Colonocytes: 115.5;Enteric stem cells: 52.1;Enteric transient amplifying cells: 63.0;Enterocytes: 47.9;Esophageal apical cells: 74.6;Loop of henle epithelial cells: 39.0;Parietal cells: 190.9;Respiratory ionocytes: 30.5;Tuft cells: 34.6" "Cell type enhanced" "Detected in some" "fibroblast: 8.4;oligodendrocyte: 5.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 10 "MAIT T-cell: 24.1;memory CD8 T-cell: 8.2" "Lineage enriched" "Detected in single" 89 "T-cells: 24.1" "Cancer enhanced" "Detected in many" "skin cancer: 26.1" "Colon - Colon enterocytes, Stomach - Parietal cells, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "Region enhanced" "Detected in some" "spinal cord: 4.9" HPA042308 Approved NA NA "Cluster 1: T-cells - Unknown function" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 12 "HPA042308: " "unprognostic (7.20e-2)" "unprognostic (2.88e-2)" "unprognostic (1.20e-1)" "unprognostic (4.92e-2)" "unprognostic (4.20e-1)" "unprognostic (6.08e-2)" "unprognostic (2.07e-1)" "potential prognostic favorable (2.65e-7)" "unprognostic (1.51e-2)" "potential prognostic favorable (1.05e-4)" "unprognostic (1.93e-1)" "unprognostic (2.74e-3)" "potential prognostic unfavorable (3.09e-5)" "unprognostic (1.77e-1)" "unprognostic (1.74e-1)" "unprognostic (1.94e-1)" "unprognostic (7.44e-2)" "unprognostic (7.32e-2)" "unprognostic (7.28e-2)" "unprognostic (1.04e-1)" "unprognostic (1.43e-2)" "unprognostic (1.15e-1)" "unprognostic (6.31e-3)" "unprognostic (2.58e-1)" "unprognostic (1.20e-2)" "unprognostic (7.23e-3)" TMEM174 "FLJ31268, MGC13034" ENSG00000164325 "Transmembrane protein 174" Q8WUU8 5 73173193-73175143 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 799 "kidney: 143.0" "Cell type enriched" "Detected in single" 14 "Proximal tubule cells: 10.8" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "Kidney Renal Clear Cell Carcinoma (TCGA): 14.7" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA037975 Enhanced NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 22: Non-specific - Mixed function" "Cluster 61: BICR 18 - Protein kinases" "Cluster 88: Proximal tubular cells - Transmembrane transport" 14 "HPA037975: " "unprognostic (1.39e-2)" "validated prognostic favorable (5.78e-8)" "validated prognostic favorable (2.07e-4)" "potential prognostic favorable (3.95e-4)" TMEM175 MGC4618 ENSG00000127419 "Transmembrane protein 175" Q9BSA9 4 932387-958656 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057160 Approved Approved "Nucleoplasm,Nuclear membrane" No No "Cluster 10: Non-specific - Membrane trafficking" "Cluster 70: Non-specific - Protein processing" "Cluster 6: Non-specific - Immune response" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 98: Neurons - Neurotransmission & signaling" "Nucleoplasm, Nuclear membrane" "HPA057160: " "unprognostic (3.00e-1)" "unprognostic (4.86e-1)" "unprognostic (6.11e-2)" "unprognostic (3.73e-1)" "unprognostic (2.31e-1)" "unprognostic (1.78e-1)" "unprognostic (4.46e-2)" "unprognostic (1.33e-1)" "unprognostic (6.65e-2)" "unprognostic (1.41e-1)" "unprognostic (4.44e-2)" "unprognostic (6.07e-2)" "potential prognostic favorable (7.32e-4)" "unprognostic (5.41e-2)" "unprognostic (3.64e-2)" "unprognostic (8.72e-2)" "unprognostic (5.77e-2)" "unprognostic (1.40e-1)" "unprognostic (1.18e-1)" "unprognostic (1.49e-1)" "unprognostic (1.60e-3)" "potential prognostic favorable (3.16e-4)" "unprognostic (8.23e-2)" "unprognostic (1.49e-1)" "unprognostic (7.00e-3)" "unprognostic (5.20e-2)" "unprognostic (6.31e-2)" "unprognostic (6.77e-2)" "unprognostic (1.62e-1)" "unprognostic (1.58e-1)" "unprognostic (1.85e-1)" TMEM176A "HCA112, MS4B1" ENSG00000002933 "Transmembrane protein 176A" Q96HP8 7 150800403-150805118 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "kidney: 351.8;liver: 1277.5" "Cell type enhanced" "Detected in many" "Colonocytes: 344.1;Enteric stem cells: 182.5;Enteric transient amplifying cells: 227.7;Enterocytes: 1155.7;Epididymal efferent duct absorptive cells: 461.6;Goblet cells: 186.2;Hepatocytes: 1030.2;Pancreatic islet cells: 195.7;Paneth cells: 189.5;Schwann cells: 203.6;Tuft cells: 311.3" "Cell type enhanced" "Detected in many" "astrocyte: 13.9;oligodendrocyte precursor cell: 10.8" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 932.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 146.6;intermediate monocyte: 98.5" "Lineage enriched" "Detected in many" 5 "monocytes: 146.6" "Cancer enhanced" "Detected in many" "colorectal cancer: 42.1;Gastric cancer: 31.7" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008770 Approved Approved Mitochondria NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 22: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 1: Enterocytes - Absorption and Digestion" 12 Mitochondria "HPA008770: " "unprognostic (5.90e-2)" "unprognostic (2.89e-2)" "unprognostic (6.32e-3)" "unprognostic (1.43e-1)" "unprognostic (1.63e-1)" "unprognostic (5.08e-2)" "unprognostic (1.48e-3)" "unprognostic (3.25e-2)" "unprognostic (2.05e-2)" "unprognostic (3.38e-1)" "potential prognostic favorable (2.03e-4)" "unprognostic (2.56e-2)" "unprognostic (1.85e-2)" "unprognostic (2.68e-1)" "unprognostic (3.47e-2)" "unprognostic (6.19e-2)" "unprognostic (1.22e-1)" "unprognostic (4.48e-2)" "unprognostic (3.74e-2)" "unprognostic (2.93e-1)" "unprognostic (1.52e-1)" "unprognostic (1.97e-2)" "unprognostic (2.48e-1)" "unprognostic (2.44e-2)" "unprognostic (3.41e-2)" "potential prognostic unfavorable (9.44e-4)" "unprognostic (2.78e-1)" "unprognostic (6.26e-3)" "unprognostic (1.08e-2)" "unprognostic (8.44e-2)" "unprognostic (4.12e-2)" TMEM176B "LR8, MS4B2" ENSG00000106565 "Transmembrane protein 176B" Q3YBM2 7 150791285-150801360 "Predicted membrane proteins, Transporters" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 1555.3" "Cell type enhanced" "Detected in many" "Colonocytes: 399.9;Enterocytes: 899.6;Epididymal efferent duct absorptive cells: 513.5;Granulosa cells: 324.4;Hepatocytes: 1286.0;Pancreatic islet cells: 316.1;Paneth cells: 239.8;Schwann cells: 375.9;Tuft cells: 311.3" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 50.2;oligodendrocyte precursor cell: 35.9" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 1272.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 866.3;intermediate monocyte: 586.7" "Lineage enriched" "Detected in many" 5 "monocytes: 866.3" "Cancer enhanced" "Detected in many" "colorectal cancer: 45.7" "Breast - Fibroblasts, Liver - Hepatocytes, Pituitary gland - Macrophages, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047509 Approved Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 22: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 1: Enterocytes - Absorption and Digestion" 4 "Golgi apparatus" "Nucleoplasm, Plasma membrane" "HPA047509: " "unprognostic (4.49e-3)" "unprognostic (3.63e-2)" "unprognostic (3.52e-2)" "unprognostic (1.86e-1)" "unprognostic (9.28e-2)" "unprognostic (2.00e-1)" "unprognostic (6.68e-3)" "unprognostic (1.25e-1)" "unprognostic (8.69e-2)" "unprognostic (2.76e-1)" "potential prognostic favorable (4.95e-6)" "unprognostic (1.82e-2)" "unprognostic (4.12e-3)" "unprognostic (1.33e-2)" "unprognostic (1.43e-2)" "unprognostic (7.78e-3)" "unprognostic (1.81e-1)" "unprognostic (1.25e-1)" "unprognostic (1.26e-1)" "unprognostic (2.11e-1)" "unprognostic (1.50e-1)" "unprognostic (1.70e-3)" "unprognostic (1.74e-1)" "unprognostic (1.59e-1)" "unprognostic (1.76e-1)" "unprognostic (2.50e-3)" "unprognostic (7.38e-2)" "unprognostic (2.79e-2)" "unprognostic (8.78e-3)" "unprognostic (4.33e-2)" "unprognostic (3.27e-2)" TMEM177 MGC10993 ENSG00000144120 "Transmembrane protein 177" Q53S58 2 119679167-119686507 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hepatocytes: 36.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pituitary gland - Somatotropes, Stomach - Mitotic cells (Stomach), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053816 Uncertain NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 77: Intestine - Digestion" "Cluster 38: Sub-cortical - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 97: Non-specific - Cellular respiration" 2 "HPA053816: " "unprognostic (3.13e-1)" "unprognostic (2.82e-2)" "unprognostic (3.49e-1)" "unprognostic (3.15e-2)" "unprognostic (3.81e-2)" "unprognostic (1.27e-2)" "unprognostic (1.49e-3)" "unprognostic (9.13e-3)" "unprognostic (1.53e-3)" "unprognostic (2.48e-1)" "unprognostic (6.08e-2)" "unprognostic (9.67e-2)" "unprognostic (1.46e-1)" "unprognostic (1.19e-3)" "unprognostic (2.76e-2)" "unprognostic (2.71e-2)" "unprognostic (6.85e-2)" "unprognostic (3.85e-2)" "unprognostic (2.15e-2)" "unprognostic (8.07e-2)" "unprognostic (1.91e-1)" "unprognostic (2.68e-1)" "unprognostic (2.98e-1)" "unprognostic (2.37e-1)" "unprognostic (3.30e-2)" "unprognostic (1.73e-1)" "unprognostic (3.61e-1)" "unprognostic (1.67e-1)" "unprognostic (5.38e-2)" "unprognostic (2.24e-1)" "unprognostic (8.94e-2)" TMEM178A "MGC33926, TMEM178" ENSG00000152154 "Transmembrane protein 178A" Q8NBL3 2 39664982-39717963 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 380.5" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 210.2;Brain inhibitory neurons: 85.6;Breast myoepithelial cells: 94.7;Distal convoluted tubule cells: 48.5;Oligodendrocyte progenitor cells: 51.6;Podocytes: 160.5;Renal connecting tubule cells: 197.8;Retinal amacrine cells: 178.7" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Glioblastoma Multiforme (TCGA): 31.5;Prostate Adenocarcinoma (TCGA): 40.8;Uterine Corpus Endometrial Carcinoma (TCGA): 18.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Rhabdoid: 18.8;testis cancer: 21.8" "Colon - Enteric glia cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052128 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 35: Non-specific - DNA binding" "Cluster 5: Rhabdoid - Unknown function" "Cluster 2: Cerebellar granular cells - Neuronal signaling" Vesicles Nucleoplasm "HPA052128: " "unprognostic (8.83e-2)" "unprognostic (1.60e-1)" "unprognostic (1.35e-1)" "unprognostic (1.38e-1)" "unprognostic (1.27e-1)" "unprognostic (9.46e-2)" "unprognostic (6.18e-3)" "unprognostic (1.91e-3)" "unprognostic (4.80e-2)" "unprognostic (7.48e-2)" "potential prognostic favorable (5.60e-4)" "unprognostic (1.60e-3)" "unprognostic (1.47e-1)" "unprognostic (1.07e-1)" "unprognostic (7.06e-2)" "unprognostic (1.87e-1)" "unprognostic (6.12e-2)" "unprognostic (1.88e-3)" "unprognostic (2.08e-2)" "unprognostic (2.87e-1)" "unprognostic (8.74e-2)" "unprognostic (2.00e-3)" "unprognostic (5.84e-2)" "unprognostic (4.66e-3)" "unprognostic (1.51e-2)" TMEM178B DKFZp547G036 ENSG00000261115 "Transmembrane protein 178B" H3BS89 7 141074064-141480380 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.7;heart muscle: 10.3;parathyroid gland: 11.2;tongue: 11.2" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 530.3;Brain inhibitory neurons: 737.5;Cardiomyocytes: 750.0;Corticotrophs: 1488.8;Lactotrophs: 950.1;Oligodendrocyte progenitor cells: 470.6;Other brain neurons: 556.2;Pancreatic islet cells: 459.5;Pituitary stem cells: 569.0;Retinal amacrine cells: 728.2;Retinal bipolar cells: 471.0;Retinal horizontal cells: 601.0;Somatotrophs: 637.7;Thyrotrophs: 796.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 8.7;Kidney Renal Papillary Cell Carcinoma (TCGA): 9.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Pituitary gland - Corticotropes, Prostate - Prostate glandular cells, Spleen - B-cells (Spleen), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048771 Uncertain Approved Nucleoli,Vesicles NA NA "Cluster 41: Striated muscle - Muscle contraction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" Vesicles Nucleoli "HPA048771: " "unprognostic (1.49e-3)" "unprognostic (7.50e-2)" "unprognostic (1.96e-1)" "unprognostic (4.10e-1)" "unprognostic (3.18e-1)" "unprognostic (2.43e-1)" "unprognostic (1.07e-1)" "unprognostic (8.87e-2)" "unprognostic (8.43e-3)" "unprognostic (1.87e-1)" "unprognostic (8.48e-2)" "potential prognostic favorable (5.58e-4)" "unprognostic (8.23e-2)" "unprognostic (2.38e-1)" "unprognostic (9.28e-2)" "unprognostic (2.36e-1)" "unprognostic (1.69e-2)" TMEM179 "C14orf90, FLJ42486, TMEM179A" ENSG00000258986 "Transmembrane protein 179" Q6ZVK1 14 104474678-104605647 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 60.6;pituitary gland: 71.1" "Group enriched" "Detected in some" 4 "Brain excitatory neurons: 21.0;Brain inhibitory neurons: 36.0;Oligodendrocyte progenitor cells: 18.4;Other brain neurons: 31.2" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 7.2;Pancreatic Adenocarcinoma (TCGA): 7.0;Testicular Germ Cell Tumor (TCGA): 9.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 23.9;prostate cancer: 16.7" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Pituitary gland - Lactotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002942 Uncertain Mitochondria NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" Mitochondria "HPA002942: " "unprognostic (1.18e-2)" "unprognostic (4.53e-2)" "unprognostic (1.64e-2)" "unprognostic (1.48e-1)" "unprognostic (2.46e-1)" "unprognostic (7.70e-3)" "unprognostic (3.61e-1)" "unprognostic (4.58e-2)" TMEM179B ENSG00000185475 "Transmembrane protein 179B" Q7Z7N9 11 62787402-62790400 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016585, HPA062068" Enhanced "Nuclear speckles" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 8: Immune cells - Immune response" "Cluster 24: Non-specific - Unknown function" "Cluster 8: Non-specific - Secretory pathway" 49 "Nuclear speckles" "HPA016585: , HPA062068: " "unprognostic (2.64e-2)" "unprognostic (1.26e-2)" "unprognostic (2.98e-1)" "unprognostic (6.83e-2)" "unprognostic (1.84e-1)" "unprognostic (2.39e-2)" "unprognostic (5.85e-2)" "unprognostic (4.24e-1)" "unprognostic (7.27e-3)" "unprognostic (1.03e-1)" "potential prognostic favorable (8.78e-4)" "unprognostic (1.85e-1)" "unprognostic (9.54e-2)" "unprognostic (7.74e-3)" "unprognostic (5.26e-2)" "unprognostic (6.63e-2)" "unprognostic (3.50e-2)" "unprognostic (2.32e-1)" "unprognostic (8.87e-2)" "unprognostic (2.29e-2)" "unprognostic (2.29e-1)" "potential prognostic unfavorable (4.55e-5)" "unprognostic (8.22e-2)" "unprognostic (2.04e-2)" "unprognostic (2.14e-1)" "unprognostic (1.71e-1)" "unprognostic (2.24e-1)" "unprognostic (4.36e-1)" "unprognostic (1.63e-1)" "unprognostic (7.73e-2)" "unprognostic (4.06e-1)" TMEM18 "DKFZp434C1714, lncND" ENSG00000151353 "Transmembrane protein 18" Q96B42 2 663877-677406 "Predicted membrane proteins, Transporters" Transcription DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040233 Approved Approved "Endoplasmic reticulum,Mitochondria" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 54: Non-specific - Ribosome" "Cluster 27: Non-specific - Mixed function" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" Mitochondria "Endoplasmic reticulum" "HPA040233: " "potential prognostic unfavorable (4.55e-4)" "unprognostic (1.93e-1)" "unprognostic (2.21e-1)" "unprognostic (7.42e-2)" "unprognostic (4.98e-2)" "unprognostic (1.21e-1)" "unprognostic (7.83e-2)" "unprognostic (1.76e-1)" "unprognostic (1.84e-2)" "unprognostic (1.85e-2)" "potential prognostic favorable (2.38e-8)" "unprognostic (1.30e-1)" "unprognostic (2.61e-2)" "unprognostic (3.51e-3)" "potential prognostic unfavorable (8.40e-4)" "unprognostic (2.04e-2)" "unprognostic (2.69e-1)" "unprognostic (2.86e-2)" "unprognostic (2.27e-1)" "unprognostic (8.83e-2)" "unprognostic (2.18e-1)" "unprognostic (8.72e-2)" "potential prognostic unfavorable (2.04e-4)" "unprognostic (6.46e-2)" "unprognostic (8.39e-3)" "potential prognostic unfavorable (9.04e-4)" "potential prognostic unfavorable (1.12e-4)" "unprognostic (6.65e-2)" "unprognostic (1.83e-1)" "unprognostic (5.01e-3)" "unprognostic (3.13e-1)" TMEM181 "GPR178, KIAA1423" ENSG00000146433 "Transmembrane protein 181" Q9P2C4 6 158536436-158635429 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Sertoli cells: 389.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040189 Enhanced Approved "Golgi apparatus,Vesicles" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 60: Stomach - Digestion" "Cluster 14: Neurons - Synaptic function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 7 Vesicles "Golgi apparatus" "HPA040189: " "unprognostic (3.09e-1)" "unprognostic (4.33e-3)" "unprognostic (1.54e-1)" "potential prognostic unfavorable (2.15e-6)" "unprognostic (2.02e-1)" "unprognostic (2.15e-2)" "unprognostic (3.97e-1)" "unprognostic (8.35e-2)" "unprognostic (8.16e-2)" "unprognostic (1.32e-1)" "unprognostic (2.58e-3)" "unprognostic (2.88e-2)" "unprognostic (2.73e-1)" "unprognostic (1.34e-2)" "unprognostic (2.64e-3)" "unprognostic (1.85e-2)" "unprognostic (3.04e-1)" "unprognostic (1.57e-1)" "unprognostic (4.99e-2)" "potential prognostic unfavorable (2.05e-4)" "unprognostic (1.52e-2)" "unprognostic (5.45e-2)" "unprognostic (6.69e-2)" "unprognostic (1.48e-1)" "unprognostic (2.21e-2)" "unprognostic (2.36e-1)" "unprognostic (2.53e-1)" "unprognostic (1.08e-1)" "unprognostic (3.82e-1)" "unprognostic (2.34e-1)" "unprognostic (1.87e-1)" TMEM182 FLJ30294 ENSG00000170417 "Transmembrane protein 182" Q6ZP80 2 102736905-103019900 "Predicted intracellular proteins, Predicted membrane proteins" Myogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 23 "heart muscle: 91.4;skeletal muscle: 141.0;tongue: 119.3" "Cell type enhanced" "Detected in many" "Breast lactating cells: 140.3;Cardiomyocytes: 239.2;Early spermatids: 117.9;Myonuclei: 234.3;Thymic myoid cells: 80.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA045861 Approved Nucleoplasm,Vesicles NA NA "Cluster 24: Non-specific - Transcription" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 43: Hindbrain - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 17 "Nucleoplasm, Vesicles" "HPA045861: " "unprognostic (6.24e-2)" "unprognostic (1.05e-1)" "unprognostic (4.13e-1)" "unprognostic (2.20e-2)" "unprognostic (3.03e-2)" "unprognostic (1.61e-1)" "unprognostic (9.53e-2)" "unprognostic (2.75e-1)" "unprognostic (4.84e-2)" "unprognostic (5.26e-2)" "unprognostic (1.06e-3)" "unprognostic (6.53e-2)" "unprognostic (9.00e-3)" "unprognostic (2.20e-3)" "potential prognostic unfavorable (8.28e-4)" "unprognostic (5.23e-2)" "unprognostic (1.39e-1)" "unprognostic (1.80e-1)" "unprognostic (3.93e-1)" "unprognostic (2.47e-1)" "unprognostic (1.13e-1)" "unprognostic (1.17e-2)" "unprognostic (1.55e-2)" "unprognostic (1.91e-1)" "unprognostic (6.46e-3)" "unprognostic (1.99e-2)" "unprognostic (8.39e-2)" "unprognostic (6.70e-2)" "unprognostic (2.51e-1)" "unprognostic (1.20e-1)" "unprognostic (2.79e-1)" TMEM183A C1orf37 ENSG00000163444 "Transmembrane protein 183A" Q8IXX5 1 203007374-203024848 "Essential proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 117.1;Late spermatids: 97.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072607 Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 1: Neurons - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 11 "Plasma membrane" "Nucleoplasm, Cell Junctions" "HPA072607: " "unprognostic (2.50e-2)" "unprognostic (5.48e-3)" "unprognostic (4.73e-2)" "unprognostic (9.28e-3)" "unprognostic (2.26e-1)" "unprognostic (2.43e-2)" "unprognostic (1.19e-1)" "potential prognostic favorable (1.64e-4)" "unprognostic (3.45e-1)" "unprognostic (4.55e-2)" "unprognostic (5.14e-3)" "unprognostic (1.92e-1)" "unprognostic (4.92e-2)" "unprognostic (1.35e-3)" "unprognostic (2.14e-2)" "unprognostic (2.82e-2)" "unprognostic (3.01e-2)" "unprognostic (1.40e-1)" "unprognostic (5.01e-1)" "unprognostic (3.53e-2)" "unprognostic (3.90e-2)" "unprognostic (5.05e-2)" "unprognostic (3.63e-1)" "unprognostic (4.14e-2)" "unprognostic (1.96e-1)" "unprognostic (8.58e-3)" "unprognostic (3.04e-1)" "unprognostic (8.83e-2)" "unprognostic (2.61e-1)" "unprognostic (2.38e-3)" "unprognostic (1.03e-1)" TMEM184A "MGC9712, SDMG1" ENSG00000164855 "Transmembrane protein 184A" Q6ZMB5 7 1542235-1560821 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 88.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 166.2;Enterocytes: 64.2;Epicardial cells: 134.2;Esophageal apical cells: 413.0;Esophageal suprabasal cells: 132.2" "Cell type enhanced" "Detected in some" "vascular associated smooth muscle cell: 2.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 72.4" "Colon - Colon enterocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA053790, HPA071312" Uncertain Uncertain Nucleoplasm NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 15: Non-specific - Transcription" "Cluster 67: Non-specific - Unknown function" "Cluster 85: Squamous epithelial cells - Keratinization" 48 Nucleoplasm "HPA053790: , HPA071312: " "unprognostic (7.95e-2)" "unprognostic (7.71e-2)" "unprognostic (3.65e-2)" "potential prognostic unfavorable (4.34e-4)" "unprognostic (1.34e-2)" "unprognostic (9.24e-2)" "unprognostic (2.27e-1)" "unprognostic (3.18e-1)" "unprognostic (1.70e-1)" "unprognostic (1.89e-1)" "unprognostic (8.39e-2)" "unprognostic (4.55e-2)" "unprognostic (2.37e-1)" "unprognostic (4.60e-3)" "unprognostic (4.63e-2)" "unprognostic (3.88e-2)" "unprognostic (4.96e-2)" "unprognostic (8.30e-2)" "unprognostic (3.21e-1)" "unprognostic (1.14e-1)" "potential prognostic unfavorable (8.54e-4)" "unprognostic (4.51e-1)" "unprognostic (6.11e-2)" "unprognostic (7.89e-3)" "unprognostic (2.86e-2)" "unprognostic (1.85e-1)" "unprognostic (2.09e-1)" "unprognostic (1.87e-2)" "unprognostic (2.26e-1)" TMEM184B "C22orf5, DKFZP586A1024, FM08, HS5O6A" ENSG00000198792 "Transmembrane protein 184B" Q9Y519 22 38219291-38273010 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Endothelial cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024076 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 6 "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA024076: " "unprognostic (1.58e-1)" "unprognostic (1.38e-1)" "unprognostic (9.74e-2)" "unprognostic (7.48e-3)" "unprognostic (6.37e-2)" "unprognostic (1.93e-1)" "unprognostic (2.75e-1)" "unprognostic (1.77e-1)" "unprognostic (9.69e-2)" "unprognostic (5.97e-3)" "unprognostic (8.27e-3)" "unprognostic (3.96e-3)" "unprognostic (5.27e-1)" "potential prognostic unfavorable (3.48e-7)" "unprognostic (3.93e-2)" "unprognostic (1.90e-3)" "unprognostic (4.90e-2)" "unprognostic (3.93e-1)" "unprognostic (8.87e-2)" "unprognostic (6.02e-3)" "unprognostic (3.70e-2)" "unprognostic (1.44e-1)" "unprognostic (6.08e-2)" "unprognostic (2.26e-1)" "unprognostic (5.63e-2)" "unprognostic (3.03e-1)" "unprognostic (1.61e-1)" "unprognostic (6.13e-2)" "unprognostic (6.43e-2)" "unprognostic (1.43e-1)" "unprognostic (2.38e-1)" TMEM184C "FLJ10846, TMEM34" ENSG00000164168 "Transmembrane protein 184C" Q9NVA4 4 147617386-147672044 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "parathyroid gland: 123.8" "Group enriched" "Detected in many" 4 "Epicardial cells: 893.7;Innate lymphoid cells: 233.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054013 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 55: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 103: Non-specific - Basic cellular processes" 6 Vesicles Nucleoplasm "HPA054013: " "unprognostic (7.29e-2)" "unprognostic (2.43e-3)" "unprognostic (5.76e-2)" "unprognostic (6.02e-3)" "unprognostic (9.85e-2)" "unprognostic (3.17e-1)" "unprognostic (1.76e-1)" "unprognostic (2.18e-2)" "unprognostic (1.16e-1)" "unprognostic (2.85e-3)" "validated prognostic favorable (3.56e-7)" "validated prognostic favorable (7.44e-5)" "unprognostic (3.83e-1)" "unprognostic (9.91e-3)" "unprognostic (4.28e-2)" "unprognostic (7.55e-2)" "unprognostic (1.23e-2)" "unprognostic (5.22e-2)" "unprognostic (4.39e-1)" "unprognostic (1.90e-2)" "potential prognostic unfavorable (2.07e-4)" "potential prognostic unfavorable (7.79e-4)" "unprognostic (6.72e-2)" "unprognostic (1.85e-1)" "unprognostic (6.35e-2)" "unprognostic (2.78e-1)" "unprognostic (8.88e-2)" "unprognostic (1.19e-1)" "unprognostic (2.46e-1)" "unprognostic (1.91e-1)" "unprognostic (3.66e-1)" TMEM185A "CXorf13, FAM11A, FRAXF" ENSG00000269556 "Transmembrane protein 185A" Q8NFB2 X 149596556-149631912 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 63.7;Platelets: 74.6;Sertoli cells: 60.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Liver - Vascular endothelial cells, Spleen - Endothelial cells, Testis - Sertoli cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048295, HPA071744" Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 35: Non-specific - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 28 "Endoplasmic reticulum" "HPA048295: , HPA071744: " "unprognostic (1.31e-1)" "unprognostic (2.14e-2)" "unprognostic (7.98e-2)" "unprognostic (5.88e-2)" "unprognostic (5.07e-2)" "unprognostic (1.05e-1)" "unprognostic (3.11e-1)" "unprognostic (1.22e-1)" "unprognostic (3.57e-2)" "potential prognostic favorable (3.44e-4)" "unprognostic (7.56e-3)" "unprognostic (4.18e-2)" "unprognostic (5.12e-2)" "unprognostic (6.60e-2)" "unprognostic (1.96e-1)" "unprognostic (2.16e-2)" "unprognostic (2.41e-1)" "unprognostic (1.00e-1)" "unprognostic (1.37e-1)" "unprognostic (6.17e-2)" "unprognostic (1.39e-2)" "unprognostic (1.02e-1)" "unprognostic (1.67e-2)" "unprognostic (8.19e-2)" "unprognostic (4.04e-2)" "unprognostic (1.28e-1)" "unprognostic (1.81e-1)" "unprognostic (5.66e-2)" TMEM185B "FAM11B, FLJ20979" ENSG00000226479 "Transmembrane protein 185B" Q9H7F4 2 120217479-120223400 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 46.9;Neutrophils: 40.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048295, HPA071744" Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" "Endoplasmic reticulum" "HPA048295: , HPA071744: " "unprognostic (3.59e-2)" "unprognostic (1.82e-2)" "unprognostic (6.04e-2)" "unprognostic (5.00e-2)" "unprognostic (2.33e-1)" "unprognostic (7.63e-2)" "unprognostic (3.19e-2)" "unprognostic (1.35e-2)" "unprognostic (1.18e-1)" "unprognostic (2.09e-1)" "unprognostic (2.17e-2)" "unprognostic (1.34e-1)" "potential prognostic unfavorable (1.38e-4)" "potential prognostic unfavorable (1.50e-5)" "unprognostic (2.54e-3)" "validated prognostic unfavorable (2.63e-4)" "validated prognostic unfavorable (9.43e-4)" "unprognostic (1.84e-1)" "unprognostic (1.55e-3)" "unprognostic (2.22e-1)" "unprognostic (8.96e-2)" "unprognostic (2.40e-2)" "unprognostic (5.41e-2)" "unprognostic (2.80e-2)" "unprognostic (2.73e-1)" "unprognostic (1.06e-1)" "unprognostic (1.95e-3)" "unprognostic (5.51e-2)" "unprognostic (5.15e-2)" "unprognostic (5.51e-2)" "unprognostic (1.20e-1)" TMEM186 "C16orf51, DKFZP564K2062" ENSG00000184857 "Transmembrane protein 186" Q96B77 16 8780384-8797642 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 45.0;Late primary spermatocytes: 55.6;Late spermatids: 190.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018226, HPA063559" Uncertain Approved "Cell Junctions" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 54: Non-specific - Transcription" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 22 "Cell Junctions" "HPA018226: , HPA063559: " "unprognostic (1.15e-1)" "unprognostic (2.30e-2)" "unprognostic (1.08e-1)" "unprognostic (6.63e-2)" "unprognostic (1.10e-1)" "unprognostic (5.33e-2)" "unprognostic (7.96e-2)" "unprognostic (7.70e-3)" "unprognostic (6.74e-2)" "unprognostic (3.43e-2)" "potential prognostic favorable (2.37e-6)" "unprognostic (4.93e-2)" "unprognostic (7.12e-2)" "unprognostic (1.23e-2)" "unprognostic (1.70e-1)" "unprognostic (8.08e-2)" "unprognostic (9.11e-2)" "unprognostic (2.28e-1)" "unprognostic (2.97e-2)" "unprognostic (3.22e-2)" "unprognostic (8.83e-2)" "unprognostic (1.86e-1)" "unprognostic (2.57e-1)" "unprognostic (5.87e-2)" "potential prognostic favorable (7.09e-4)" "unprognostic (2.55e-1)" "unprognostic (2.19e-1)" "unprognostic (1.07e-1)" "unprognostic (1.83e-1)" "unprognostic (7.12e-2)" "unprognostic (2.07e-1)" TMEM187 "CXorf12, DXS9878E, ITBA1" ENSG00000177854 "Transmembrane protein 187" Q14656 X 153972754-153983194 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" HPA038134 Uncertain Approved Nucleoli,Cytosol NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 70: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 36: Non-specific - mRNA processing" "Cluster 97: Non-specific - Cellular respiration" 13 "Nucleoli, Cytosol" "HPA038134: " "unprognostic (4.73e-3)" "unprognostic (1.37e-2)" "unprognostic (6.93e-2)" "unprognostic (5.79e-3)" "unprognostic (1.39e-1)" "unprognostic (1.30e-2)" "unprognostic (1.48e-1)" "unprognostic (2.40e-1)" "unprognostic (1.71e-1)" "unprognostic (3.12e-1)" "potential prognostic favorable (2.02e-5)" "unprognostic (6.92e-2)" "potential prognostic favorable (1.60e-4)" "unprognostic (4.54e-2)" "unprognostic (2.53e-2)" "unprognostic (2.62e-1)" "unprognostic (3.45e-2)" "unprognostic (1.00e-1)" "unprognostic (1.84e-1)" "unprognostic (5.73e-2)" "unprognostic (2.85e-2)" "unprognostic (2.35e-2)" "unprognostic (4.63e-2)" "unprognostic (1.15e-2)" "unprognostic (3.10e-2)" "unprognostic (3.27e-2)" "unprognostic (1.29e-1)" "unprognostic (3.18e-2)" "unprognostic (1.08e-1)" "unprognostic (2.49e-1)" "unprognostic (1.88e-1)" TMEM19 FLJ10936 ENSG00000139291 "Transmembrane protein 19" Q96HH6 12 71686082-71705047 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal suprabasal cells: 62.3;Late spermatids: 130.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016830 Approved NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 38: Non-specific - Transcription" "Cluster 67: Plasma cells - Plasma cell differentiation" 34 "HPA016830: " "unprognostic (1.61e-1)" "unprognostic (1.36e-1)" "unprognostic (1.38e-1)" "unprognostic (3.76e-1)" "unprognostic (3.24e-1)" "unprognostic (4.07e-2)" "unprognostic (2.06e-1)" "unprognostic (2.95e-1)" "unprognostic (1.24e-1)" "unprognostic (1.14e-3)" "potential prognostic favorable (2.55e-6)" "unprognostic (1.36e-1)" "unprognostic (4.51e-1)" "unprognostic (3.10e-2)" "unprognostic (5.78e-3)" "unprognostic (2.10e-2)" "unprognostic (4.46e-2)" "unprognostic (5.17e-2)" "unprognostic (3.02e-1)" "unprognostic (6.53e-2)" "unprognostic (8.68e-2)" "unprognostic (1.36e-1)" "unprognostic (3.22e-1)" "unprognostic (1.36e-2)" "unprognostic (6.52e-3)" "unprognostic (1.24e-1)" "unprognostic (1.35e-1)" "unprognostic (2.14e-1)" "unprognostic (1.39e-1)" "unprognostic (2.82e-2)" "unprognostic (3.59e-2)" TMEM190 MDAC1 ENSG00000160472 "Transmembrane protein 190" Q8WZ59 19 55376826-55378246 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "fallopian tube: 129.9;testis: 54.8" "Cell type enhanced" "Detected in some" "Early spermatids: 793.5;Endometrial ciliated cells: 391.2;Epididymal efferent duct ciliated cells: 511.2;Fallopian tube ciliated cells: 1011.1;Late primary spermatocytes: 201.9;Late spermatids: 217.9;Respiratory ciliated cells: 1780.7" "Cell type enriched" "Detected in single" 292 "ependymal cell: 33.8" "Cancer enriched" "Detected in many" 4 "Uterine Corpus Endometrial Carcinoma (TCGA): 48.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal medulla cells, Lung - Respiratory ciliated cells, Testis - Late spermatids" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "cerebellum: 1.9" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 2: Neurons - Nucleosome" "Cluster 15: Kidney cancer - Membrane components" "Cluster 107: Ciliated cells - Cilia assembly & function" 10 "unprognostic (2.57e-2)" "unprognostic (6.35e-2)" "unprognostic (2.07e-1)" "unprognostic (2.63e-1)" "unprognostic (1.11e-1)" "unprognostic (2.20e-2)" "unprognostic (1.09e-1)" "unprognostic (1.66e-1)" "unprognostic (2.70e-1)" "unprognostic (2.04e-1)" "unprognostic (1.77e-1)" "unprognostic (2.79e-2)" "unprognostic (1.68e-1)" "unprognostic (2.26e-1)" "unprognostic (1.63e-2)" "unprognostic (2.87e-1)" "unprognostic (2.34e-1)" "unprognostic (2.52e-1)" TMEM191B ENSG00000278558 "Transmembrane protein 191B" P0C7N4 22 18527802-18530573 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 29 "testis: 86.1" "Group enriched" "Detected in some" 4 "Early spermatids: 110.7;Late spermatids: 171.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Testis - Late spermatids" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 79: Testis - Spermatogenesis" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" "unprognostic (5.16e-1)" TMEM191C ENSG00000206140 "Transmembrane protein 191C" A6NGB0 22 21466423-21471269 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 60 "testis: 39.4" "Group enriched" "Detected in many" 7 "Early spermatids: 800.5;Late spermatids: 1294.6" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 66: Non-specific - Mitochondria" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" "unprognostic (6.21e-2)" "potential prognostic unfavorable (7.35e-4)" TMEM192 FLJ38482 ENSG00000170088 "Transmembrane protein 192" Q8IY95 4 165070608-165208549 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Retinal pigment epithelial cells: 456.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014717, HPA024110" Enhanced Supported Nucleoplasm,Endosomes,Lysosomes NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 76: Non-specific - Metabolism" "Cluster 55: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" 27 "Endosomes, Lysosomes" Nucleoplasm "HPA014717: , HPA024110: " "unprognostic (3.86e-3)" "unprognostic (1.29e-2)" "unprognostic (5.13e-2)" "unprognostic (1.08e-3)" "unprognostic (5.66e-2)" "unprognostic (1.41e-1)" "unprognostic (6.12e-2)" "unprognostic (6.62e-3)" "unprognostic (1.68e-2)" "unprognostic (1.31e-2)" "validated prognostic favorable (1.57e-9)" "validated prognostic favorable (8.41e-4)" "unprognostic (2.26e-2)" "unprognostic (1.17e-1)" "unprognostic (3.16e-2)" "unprognostic (2.13e-1)" "unprognostic (4.55e-1)" "unprognostic (1.49e-3)" "unprognostic (2.81e-2)" "unprognostic (5.14e-2)" "unprognostic (1.49e-2)" "unprognostic (4.98e-2)" "unprognostic (2.28e-1)" "unprognostic (9.03e-2)" "potential prognostic favorable (4.69e-4)" "unprognostic (3.77e-1)" "unprognostic (1.80e-2)" "unprognostic (2.44e-1)" "unprognostic (4.23e-2)" "unprognostic (3.07e-2)" "unprognostic (2.58e-1)" TMEM196 MGC42090 ENSG00000173452 "Transmembrane protein 196" Q5HYL7 7 19719315-19773617 "Predicted intracellular proteins, Predicted membrane proteins" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.5;retina: 19.5" "Cell type enhanced" "Detected in some" "Brain inhibitory neurons: 60.9;Endometrial stromal cells: 254.6;Lactotrophs: 166.0;Oligodendrocyte progenitor cells: 104.8;Other brain neurons: 114.3;Pancreatic islet cells: 82.2;Retinal amacrine cells: 80.5;Retinal bipolar cells: 330.3;Somatotrophs: 175.0" "Cell type enhanced" "Detected in many" "eccentric medium spiny neuron: 168.3;mammillary body: 167.5" "Cancer enhanced" "Detected in single" "Glioblastoma Multiforme (TCGA): 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Neuroblastoma: 2.2" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" HPA043163 Uncertain Uncertain "Nucleoplasm,Golgi apparatus" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "Nucleoplasm, Golgi apparatus" "HPA043163: " "unprognostic (3.81e-2)" "unprognostic (7.40e-2)" TMEM198 "MGC99813, TMEM198A" ENSG00000188760 "Transmembrane protein 198" Q66K66 2 219543663-219550595 "Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 42.5;Cardiomyocytes: 26.4;Decidual stromal cells: 15.6;Epicardial cells: 40.9;Neuroendocrine cells: 16.4;Pancreatic islet cells: 14.4;Tuft cells: 46.1" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 19.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 19.7" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042385, HPA062897" Enhanced Approved Vesicles NA NA "Cluster 70: Non-specific - Protein processing" "Cluster 29: Forebrain - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" Vesicles "HPA042385: , HPA062897: " "unprognostic (2.80e-3)" "unprognostic (1.71e-2)" "unprognostic (1.62e-1)" "unprognostic (2.60e-2)" "potential prognostic unfavorable (6.16e-4)" "unprognostic (2.07e-2)" "unprognostic (1.86e-2)" "unprognostic (4.15e-2)" "unprognostic (1.87e-1)" "unprognostic (1.11e-1)" "unprognostic (1.14e-2)" "unprognostic (1.87e-1)" "unprognostic (2.25e-1)" "unprognostic (2.35e-1)" "unprognostic (4.01e-3)" "unprognostic (1.25e-1)" "unprognostic (1.23e-1)" "unprognostic (1.87e-1)" "unprognostic (9.39e-2)" "unprognostic (1.31e-1)" "unprognostic (1.58e-1)" "potential prognostic favorable (7.93e-4)" "unprognostic (1.45e-1)" "unprognostic (2.75e-1)" "unprognostic (1.28e-1)" "unprognostic (1.71e-1)" "unprognostic (2.71e-1)" "unprognostic (9.83e-2)" "unprognostic (1.02e-1)" "unprognostic (3.27e-2)" "unprognostic (1.89e-1)" TMEM199 "C17orf32, MGC45714, VMA12, VPH2" ENSG00000244045 "Transmembrane protein 199" Q8N511 17 28357642-28363683 "Disease related genes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 10.9;Bergmann glia: 16.5;Brain excitatory neurons: 12.9;Brain inhibitory neurons: 12.1;Hofbauer cells: 9.5;Microglia: 13.2;Oligodendrocyte progenitor cells: 11.3;Oligodendrocytes: 14.8;Other brain neurons: 13.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027051 Uncertain NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" 31 "HPA027051: " "unprognostic (5.31e-2)" "unprognostic (3.37e-2)" "unprognostic (2.57e-1)" "unprognostic (3.68e-1)" "unprognostic (2.48e-1)" "unprognostic (1.46e-1)" "unprognostic (4.06e-2)" "unprognostic (1.35e-2)" "unprognostic (1.14e-1)" "unprognostic (7.33e-3)" "potential prognostic favorable (1.77e-4)" "unprognostic (1.15e-1)" "unprognostic (2.12e-2)" "validated prognostic unfavorable (1.86e-5)" "validated prognostic unfavorable (3.14e-5)" "unprognostic (9.48e-2)" "unprognostic (2.33e-1)" "unprognostic (1.16e-2)" "unprognostic (1.20e-2)" "unprognostic (7.75e-2)" "unprognostic (1.30e-1)" "unprognostic (2.52e-2)" "unprognostic (1.65e-2)" "unprognostic (2.55e-1)" "unprognostic (1.58e-1)" "unprognostic (1.52e-1)" "unprognostic (4.78e-3)" "unprognostic (2.77e-1)" "unprognostic (5.25e-1)" "unprognostic (1.55e-1)" "unprognostic (1.60e-2)" TMEM200A "KIAA1913, TTMC" ENSG00000164484 "Transmembrane protein 200A" Q86VY9 6 130366017-130443067 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 36.8" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 42.2;Gonadotrophs: 48.7;Lactotrophs: 58.4;Neuroendocrine cells: 59.1;Ocular epithelial cells: 37.6;Pancreatic islet cells: 62.4;Proximal tubule cells: 41.1;Retinal bipolar cells: 68.8;Retinal horizontal cells: 36.1;Thymocytes: 30.5;Thyrotrophs: 31.3" "Cell type enhanced" "Detected in many" "hippocampal CA1-3: 66.6;hippocampal dentate gyrus: 103.0;leukocyte: 60.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "NK-cell: 4.0" "Lineage enriched" "Detected in single" 5 "NK-cells: 4.0" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Pituitary gland - Lactotropes, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014396 Uncertain NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 14: Neurons - Synaptic function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 19 "HPA014396: " "unprognostic (3.89e-2)" "unprognostic (1.37e-1)" "unprognostic (2.82e-1)" "unprognostic (7.09e-2)" "unprognostic (9.91e-3)" "potential prognostic favorable (5.78e-5)" "unprognostic (7.88e-2)" "unprognostic (4.23e-2)" "unprognostic (1.72e-1)" "potential prognostic favorable (2.66e-7)" "unprognostic (2.79e-3)" "unprognostic (5.69e-2)" "unprognostic (2.62e-1)" "unprognostic (7.79e-2)" "unprognostic (3.09e-3)" "unprognostic (8.83e-2)" "unprognostic (6.08e-2)" "unprognostic (4.12e-2)" "unprognostic (1.81e-3)" "unprognostic (1.03e-1)" "unprognostic (2.86e-1)" "unprognostic (2.26e-1)" "unprognostic (6.18e-2)" "unprognostic (7.53e-3)" "unprognostic (1.27e-3)" "unprognostic (1.30e-1)" "unprognostic (1.50e-1)" "unprognostic (3.09e-3)" TMEM200B TTMB ENSG00000253304 "Transmembrane protein 200B" Q69YZ2 1 29119429-29123903 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 58.0" "Cell type enhanced" "Detected in some" "Adipocytes: 12.9;Cardiomyocytes: 18.3;Choroid plexus epithelial cells: 6.5;Decidual stromal cells: 12.4;Endometrial stromal cells: 6.7;Fibroblasts: 8.9;Leydig cells: 12.9;Ovarian stromal cells: 9.3;Pericytes: 9.9;Peritubular myoid cells: 15.2;Respiratory deuterosomal cells: 7.3;Sertoli cells: 8.2;Smooth muscle cells: 10.9;Vascular smooth muscle cells: 11.5" "Group enriched" "Detected in some" 4 "choroid plexus epithelial cell: 5.9;fibroblast: 14.8;pericyte: 16.0;vascular associated smooth muscle cell: 11.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Liver - Hepatic stellate cells, Pituitary gland - Fibroblasts, Testis - Sertoli cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 12.2" HPA055254 Uncertain NA NA "Cluster 75: Ovary - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" "HPA055254: " "unprognostic (9.82e-2)" "unprognostic (6.94e-2)" "unprognostic (1.08e-1)" "unprognostic (3.37e-3)" "unprognostic (1.58e-2)" "unprognostic (5.07e-2)" "unprognostic (2.94e-3)" "unprognostic (3.91e-2)" "unprognostic (2.78e-1)" "unprognostic (3.00e-2)" "unprognostic (1.31e-1)" "unprognostic (8.74e-2)" "unprognostic (2.89e-2)" "unprognostic (1.59e-1)" "unprognostic (3.00e-2)" "unprognostic (3.74e-2)" "unprognostic (3.02e-3)" "unprognostic (6.25e-2)" "unprognostic (1.38e-1)" "unprognostic (1.77e-1)" "unprognostic (5.56e-2)" "unprognostic (2.49e-2)" "unprognostic (1.95e-1)" "unprognostic (2.11e-1)" "unprognostic (1.15e-2)" "unprognostic (4.37e-2)" "unprognostic (3.49e-1)" "unprognostic (2.56e-3)" "unprognostic (3.25e-1)" "unprognostic (2.21e-1)" "unprognostic (2.04e-1)" TMEM200C TTMA ENSG00000206432 "Transmembrane protein 200C" A6NKL6 18 5882072-5895955 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 3.7;brain: 3.2;salivary gland: 5.5" "Cell type enhanced" "Detected in some" "Adrenal cortex cells: 9.8;Adrenal medulla cells: 10.6;Bergmann glia: 14.6;Brain inhibitory neurons: 14.2;Lacrimal acinar cells: 8.2;Oligodendrocyte progenitor cells: 26.1;Other brain neurons: 7.7;Podocytes: 36.1;Retinal amacrine cells: 26.7" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 4.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "Rhabdoid: 3.5" "Colon - Enteric glia cells, Kidney - Podocytes, Prostate - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA047253, HPA050490" Uncertain Approved Microtubules NA NA "Cluster 68: Non-specific - Basic cellular processes" "Cluster 1: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 109: Neurons - Neuronal signaling" Microtubules "HPA047253: , HPA050490: " "unprognostic (2.65e-1)" "unprognostic (1.83e-1)" "unprognostic (6.09e-3)" "unprognostic (1.62e-1)" "unprognostic (1.41e-1)" "unprognostic (6.47e-2)" "unprognostic (9.60e-2)" TMEM201 "Ima1, NET5, RP13-15M17.2, SAMP1" ENSG00000188807 "Transmembrane protein 201" Q5SNT2 1 9588911-9614877 "Predicted membrane proteins, Transporters" Angiogenesis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 40.6" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Endothelial cells, Pituitary gland - Corticotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB039039 Approved Supported "Nucleoplasm,Nuclear membrane" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 37: Non-specific - mRNA processing" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 34 "Nuclear membrane" Nucleoplasm "CAB039039: " "unprognostic (1.47e-1)" "unprognostic (4.68e-2)" "unprognostic (3.65e-2)" "unprognostic (1.12e-1)" "unprognostic (1.01e-1)" "unprognostic (1.39e-1)" "unprognostic (2.91e-1)" "unprognostic (4.08e-1)" "unprognostic (6.00e-2)" "unprognostic (1.89e-2)" "unprognostic (1.03e-1)" "unprognostic (1.28e-1)" "unprognostic (2.16e-1)" "validated prognostic unfavorable (2.48e-7)" "validated prognostic unfavorable (2.09e-4)" "unprognostic (2.21e-1)" "unprognostic (7.99e-2)" "unprognostic (2.42e-2)" "unprognostic (3.31e-2)" "unprognostic (4.31e-2)" "unprognostic (8.79e-3)" "potential prognostic favorable (5.41e-4)" "unprognostic (4.31e-1)" "unprognostic (3.37e-1)" "unprognostic (3.27e-1)" "unprognostic (1.76e-2)" "unprognostic (2.10e-1)" "unprognostic (9.49e-2)" "unprognostic (6.36e-2)" "unprognostic (7.90e-3)" "unprognostic (3.13e-1)" TMEM202 FLJ27523 ENSG00000187806 "Transmembrane protein 202" A6NGA9 15 72398302-72408367 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 115 "testis: 11.5" "Group enriched" "Detected in some" 12 "Early spermatids: 66.9;Late primary spermatocytes: 150.0;Late spermatids: 93.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Low region specificity" "Detected in many" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 72: Neuronal - Signal transduction" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" TMEM203 "HBEBP1, MGC14327" ENSG00000187713 "Transmembrane protein 203" Q969S6 9 137204082-137205648 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 27: Non-specific - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 11: Muller glia cells - Retinal homeostasis" 34 "unprognostic (3.11e-2)" "unprognostic (8.97e-3)" "unprognostic (1.29e-2)" "unprognostic (1.53e-1)" "unprognostic (5.74e-3)" "unprognostic (1.62e-2)" "unprognostic (2.78e-1)" "unprognostic (1.97e-2)" "unprognostic (1.24e-1)" "unprognostic (5.45e-1)" "potential prognostic favorable (4.53e-5)" "unprognostic (4.97e-3)" "potential prognostic favorable (1.19e-4)" "unprognostic (4.38e-2)" "potential prognostic unfavorable (1.66e-5)" "unprognostic (5.63e-2)" "unprognostic (5.11e-2)" "unprognostic (4.20e-1)" "unprognostic (4.92e-2)" "unprognostic (3.34e-1)" "unprognostic (1.71e-1)" "unprognostic (2.62e-3)" "unprognostic (2.29e-1)" "unprognostic (4.24e-2)" "unprognostic (2.22e-2)" "unprognostic (4.32e-1)" "unprognostic (2.19e-2)" "unprognostic (5.15e-2)" "unprognostic (4.06e-2)" "unprognostic (1.88e-1)" "unprognostic (4.62e-2)" TMEM204 "C16orf30, CLP24, FLJ20898" ENSG00000131634 "Transmembrane protein 204" Q9BSN7 16 1528688-1555580 "Predicted membrane proteins, Transporters" "Stress response" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 41.3;Epicardial cells: 63.7;Fibroblasts: 38.9;Hepatic stellate cells: 83.9;Lymphatic endothelial cells: 82.4;Medullary thymic epithelial cells: 74.4;Pericytes: 84.4;Peritubular myoid cells: 71.5;Platelets: 64.7;Thymic myoid cells: 55.7;Vascular endothelial cells: 132.5" "Cell type enhanced" "Detected in many" "endothelial cell: 130.7;fibroblast: 52.3;pericyte: 79.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 157.0" "Lineage enriched" "Detected in many" 5 "T-cells: 157.0" "Cancer enhanced" "Detected in many" "Sarcoma: 7.4;skin cancer: 7.2" "Liver - Vascular endothelial cells, Pituitary gland - Endothelial cells, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014028 Approved NA NA "Cluster 11: T-cells - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 6 "HPA014028: " "unprognostic (4.26e-1)" "unprognostic (2.31e-1)" "unprognostic (1.19e-1)" "unprognostic (1.45e-1)" "unprognostic (4.12e-3)" "unprognostic (1.75e-1)" "unprognostic (1.01e-1)" "unprognostic (1.81e-1)" "unprognostic (1.05e-2)" "unprognostic (3.25e-1)" "validated prognostic favorable (7.16e-8)" "validated prognostic favorable (1.29e-5)" "potential prognostic unfavorable (1.90e-4)" "unprognostic (1.58e-3)" "potential prognostic favorable (6.94e-4)" "unprognostic (3.05e-2)" "unprognostic (2.55e-1)" "unprognostic (5.40e-3)" "unprognostic (2.10e-1)" "unprognostic (2.58e-1)" "unprognostic (1.55e-3)" "unprognostic (1.16e-1)" "unprognostic (9.94e-3)" "unprognostic (1.52e-1)" "unprognostic (1.65e-1)" "unprognostic (3.79e-2)" "potential prognostic unfavorable (5.28e-4)" "unprognostic (7.35e-3)" "unprognostic (7.26e-2)" "unprognostic (8.09e-2)" "unprognostic (2.12e-1)" TMEM205 "MBC3205, UNQ501" ENSG00000105518 "Transmembrane protein 205" Q6UW68 19 11342776-11346518 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 267.9;Endometrial secretory cells: 98.9;Gastric chief cells: 100.5;Late spermatids: 459.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041504 Approved Approved "Nucleoplasm,Nuclear membrane,Endoplasmic reticulum" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 21: Non-specific - Metabolism" "Cluster 23: Non-specific - Transcription" "Cluster 67: Plasma cells - Plasma cell differentiation" 25 "Endoplasmic reticulum" "Nucleoplasm, Nuclear membrane" "HPA041504: " "unprognostic (1.38e-2)" "unprognostic (7.79e-2)" "unprognostic (1.02e-1)" "unprognostic (2.07e-1)" "unprognostic (1.23e-1)" "unprognostic (2.15e-2)" "unprognostic (2.47e-2)" "unprognostic (4.02e-2)" "unprognostic (2.13e-1)" "unprognostic (2.17e-1)" "potential prognostic favorable (9.81e-10)" "unprognostic (3.01e-1)" "unprognostic (8.92e-2)" "unprognostic (5.10e-2)" "unprognostic (4.22e-2)" "unprognostic (2.24e-1)" "unprognostic (2.24e-1)" "unprognostic (1.53e-1)" "unprognostic (4.35e-1)" "unprognostic (3.49e-2)" "unprognostic (2.67e-2)" "unprognostic (3.29e-3)" "unprognostic (1.02e-2)" "unprognostic (9.88e-3)" "unprognostic (2.88e-1)" "unprognostic (3.04e-1)" "unprognostic (4.77e-2)" "unprognostic (3.06e-1)" "unprognostic (8.44e-2)" "unprognostic (2.27e-1)" "unprognostic (8.45e-2)" TMEM207 ENSG00000198398 "Transmembrane protein 207" Q6UWW9 3 190428655-190449901 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 114 "kidney: 16.6" "Cell type enriched" "Detected in some" 14 "Loop of henle epithelial cells: 33.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA014332 Uncertain NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 9 "HPA014332: " TMEM208 "hSND2, HSPC171" ENSG00000168701 "Transmembrane protein 208" Q9BTX3 16 67227103-67229278 "Predicted membrane proteins, Transporters" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 249.5;Plasma cells: 268.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041868, HPA041949" Supported NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 21: Non-specific - Metabolism" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 8: Non-specific - Secretory pathway" 20 "HPA041868: , HPA041949: " "unprognostic (6.45e-3)" "unprognostic (4.22e-2)" "unprognostic (1.46e-2)" "unprognostic (1.56e-1)" "unprognostic (2.62e-3)" "unprognostic (2.14e-2)" "unprognostic (3.37e-2)" "unprognostic (2.31e-1)" "potential prognostic unfavorable (1.07e-4)" "unprognostic (7.36e-2)" "unprognostic (2.97e-2)" "potential prognostic unfavorable (7.97e-4)" "unprognostic (7.38e-2)" "unprognostic (2.15e-3)" "unprognostic (1.40e-1)" "unprognostic (1.20e-1)" "unprognostic (1.51e-1)" "unprognostic (3.44e-2)" "unprognostic (3.47e-1)" "unprognostic (3.07e-1)" "unprognostic (2.64e-1)" "unprognostic (2.46e-1)" "unprognostic (1.13e-1)" "unprognostic (1.51e-1)" "unprognostic (1.58e-1)" "unprognostic (2.08e-2)" "unprognostic (6.91e-2)" "unprognostic (9.98e-2)" "unprognostic (4.00e-1)" "unprognostic (1.37e-1)" "unprognostic (3.39e-1)" TMEM209 "FLJ14803, NET31" ENSG00000146842 "Transmembrane protein 209" Q96SK2 7 130164713-130207770 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 86.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031678 Uncertain Approved "Nuclear membrane,Nuclear speckles,Vesicles" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 61: Non-specific - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 39: Non-specific - Transcription" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 7 "Nuclear membrane, Nuclear speckles, Vesicles" "HPA031678: " "unprognostic (1.25e-1)" "unprognostic (2.42e-1)" "unprognostic (1.37e-1)" "unprognostic (6.71e-2)" "unprognostic (1.99e-1)" "unprognostic (1.38e-1)" "unprognostic (7.50e-2)" "potential prognostic unfavorable (1.32e-4)" "unprognostic (6.63e-2)" "unprognostic (1.80e-3)" "unprognostic (2.48e-2)" "unprognostic (2.32e-1)" "unprognostic (1.31e-1)" "unprognostic (2.77e-3)" "unprognostic (3.03e-2)" "unprognostic (1.01e-2)" "unprognostic (1.15e-2)" "unprognostic (9.40e-3)" "unprognostic (1.46e-1)" "unprognostic (6.98e-2)" "unprognostic (5.31e-2)" "unprognostic (6.57e-2)" "unprognostic (1.70e-1)" "unprognostic (1.44e-1)" "unprognostic (2.07e-1)" "unprognostic (1.54e-1)" "unprognostic (1.45e-1)" "unprognostic (8.39e-2)" "unprognostic (3.24e-1)" "unprognostic (6.11e-3)" "unprognostic (1.92e-2)" TMEM210 ENSG00000185863 "Transmembrane protein 210" A6NLX4 9 137170858-137172056 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "testis: 32.7" "Group enriched" "Detected in some" 7 "Early spermatids: 957.0;Late spermatids: 2538.9" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Prostate Adenocarcinoma (TCGA): 1.1" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 33 "plasmacytoid DC: 3.3" "Lineage enriched" "Detected in single" 33 "dendritic cells: 3.3" "Cancer enhanced" "Detected in single" "prostate cancer: 2.0" "Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Testis - Late spermatids" "Not detected" "Not detected" HPA066907 Enhanced NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 79: Testis - Spermatogenesis" "Cluster 60: Prostate cancer - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" "HPA066907: " "unprognostic (2.61e-1)" TMEM212 FLJ23172 ENSG00000186329 "Transmembrane protein 212" A6NML5 3 171843349-171938715 "Predicted membrane proteins, Transporters" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 4 "fallopian tube: 28.3" "Group enriched" "Detected in some" 7 "Fallopian tube ciliated cells: 124.1;Respiratory ciliated cells: 255.0" "Cell type enhanced" "Detected in some" "ependymal cell: 21.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA045736 Approved "Nucleoli fibrillar center,Endoplasmic reticulum" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 9: Non-specific - Receptor signaling" "Cluster 56: Non-specific - Sensory perception" "Cluster 107: Ciliated cells - Cilia assembly & function" "Nucleoli fibrillar center, Endoplasmic reticulum" "HPA045736: " "unprognostic (9.43e-2)" "unprognostic (5.05e-2)" "unprognostic (2.81e-1)" "unprognostic (4.23e-3)" "unprognostic (8.05e-2)" "unprognostic (1.62e-2)" "unprognostic (1.07e-1)" "potential prognostic unfavorable (9.54e-4)" "potential prognostic unfavorable (7.19e-4)" "unprognostic (5.92e-3)" "unprognostic (3.51e-1)" "unprognostic (3.64e-1)" "unprognostic (2.15e-3)" "unprognostic (1.87e-1)" "unprognostic (7.14e-2)" "unprognostic (9.45e-3)" "unprognostic (1.43e-1)" "unprognostic (4.86e-2)" "unprognostic (1.83e-1)" "unprognostic (1.27e-2)" "unprognostic (1.21e-1)" "unprognostic (2.34e-1)" "unprognostic (2.68e-2)" "unprognostic (9.40e-2)" "unprognostic (3.40e-1)" "unprognostic (2.49e-1)" "unprognostic (1.47e-2)" "unprognostic (4.99e-2)" TMEM213 ENSG00000214128 "Transmembrane protein 213" A2RRL7 7 138797952-138838101 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 12 "kidney: 70.9;salivary gland: 49.2" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 237.9;Distal convoluted tubule cells: 316.0;Epididymal clear cells: 951.3;Lacrimal acinar cells: 118.7;Renal collecting duct intercalated cells: 590.5;Renal connecting tubule cells: 174.1;Salivary duct cells: 423.2" "Cell type enhanced" "Detected in many" "hippocampal dentate gyrus: 8.3" "Cancer enriched" "Detected in many" 35 "Kidney Chromophobe (TCGA): 389.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.1;NK-cell: 1.9" "Group enriched" "Detected in many" 5 "granulocytes: 2.1;NK-cells: 1.9" "Group enriched" "Detected in some" 4 "Gastric cancer: 1.2;Sarcoma: 1.4" "Breast - Breast glandular cells (progenitors), Kidney - Intercalated cells, Minor Salivary Gland - Minor salivary gland ductal cells, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA054059 Enhanced NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 72: Kidney - Transmembrane transport" "Cluster 48: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" "HPA054059: " "unprognostic (4.15e-2)" "unprognostic (1.37e-2)" "unprognostic (6.11e-2)" "unprognostic (8.23e-2)" "unprognostic (3.44e-3)" "unprognostic (9.38e-2)" "unprognostic (1.09e-1)" "unprognostic (3.36e-2)" "unprognostic (1.57e-3)" "unprognostic (1.00e-2)" "unprognostic (3.26e-2)" "potential prognostic unfavorable (6.11e-4)" "unprognostic (3.52e-2)" "unprognostic (6.05e-2)" "unprognostic (1.28e-1)" "unprognostic (7.26e-2)" TMEM214 FLJ20254 ENSG00000119777 "Transmembrane protein 214" Q6NUQ4 2 27032910-27041694 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 79.7;Syncytiotrophoblasts: 84.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034551 Supported "Endoplasmic reticulum,Golgi apparatus,Cytosol" NA NA "Cluster 32: Basophils - Transcription" "Cluster 70: Non-specific - Protein processing" "Cluster 44: Non-specific - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 8: Non-specific - Secretory pathway" 6 "Endoplasmic reticulum, Golgi apparatus, Cytosol" "HPA034551: " "unprognostic (7.82e-2)" "unprognostic (7.73e-3)" "unprognostic (1.78e-1)" "unprognostic (4.62e-3)" "unprognostic (1.16e-1)" "unprognostic (3.35e-1)" "unprognostic (1.20e-1)" "unprognostic (7.69e-2)" "unprognostic (7.15e-2)" "unprognostic (2.78e-1)" "unprognostic (3.11e-2)" "unprognostic (6.26e-3)" "unprognostic (4.22e-2)" "unprognostic (7.16e-3)" "potential prognostic unfavorable (5.15e-4)" "unprognostic (4.64e-2)" "unprognostic (1.13e-2)" "unprognostic (1.21e-2)" "unprognostic (8.36e-2)" "unprognostic (1.72e-1)" "unprognostic (9.30e-2)" "unprognostic (4.44e-2)" "unprognostic (5.23e-3)" "unprognostic (1.43e-1)" "unprognostic (2.09e-1)" "unprognostic (1.49e-2)" "unprognostic (1.32e-1)" "unprognostic (2.33e-1)" "unprognostic (1.75e-1)" "unprognostic (8.12e-2)" "unprognostic (3.83e-1)" TMEM215 ENSG00000188133 "Transmembrane protein 215" Q68D42 9 32783540-32789201 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 7 "retina: 16.9" "Group enriched" "Detected in some" 15 "Early spermatids: 157.5;Late spermatids: 574.8;Retinal bipolar cells: 477.0" "Cell type enhanced" "Detected in many" "hippocampal CA4: 13.8;medium spiny neuron: 11.6;midbrain-derived inhibitory: 32.7" "Cancer enriched" "Detected in single" 17 "Thyroid Carcinoma (TCGA): 8.0" "Region enhanced" "Detected in many" "hypothalamus: 13.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Minor Salivary Gland - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA063207 Approved Nucleoplasm,Vesicles NA NA "Cluster 42: Retina - Visual perception" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "Nucleoplasm, Vesicles" "HPA063207: " "unprognostic (1.27e-1)" "unprognostic (2.81e-2)" TMEM216 "CORS2, HSPC244, JBTS2, MGC13379, MKS2" ENSG00000187049 "Transmembrane protein 216" Q9P0N5 11 61392393-61398866 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome, Meckel syndrome, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 232.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 94: Gonadal somatic cells - Mixed function" "unprognostic (4.05e-1)" "unprognostic (1.43e-1)" "unprognostic (3.45e-2)" "unprognostic (8.50e-2)" "unprognostic (5.99e-2)" "unprognostic (1.17e-1)" "potential prognostic unfavorable (8.78e-4)" "unprognostic (3.01e-3)" "unprognostic (1.67e-1)" "unprognostic (8.60e-2)" "unprognostic (1.21e-2)" "unprognostic (2.22e-3)" "unprognostic (2.68e-2)" "unprognostic (1.39e-3)" "unprognostic (3.28e-3)" "unprognostic (2.18e-2)" "unprognostic (3.35e-2)" "unprognostic (4.06e-2)" "unprognostic (9.80e-2)" "unprognostic (1.46e-1)" "unprognostic (1.88e-1)" "unprognostic (4.55e-3)" "unprognostic (1.52e-1)" "unprognostic (9.26e-2)" "unprognostic (1.00e-1)" "potential prognostic unfavorable (5.12e-4)" "unprognostic (1.18e-1)" "unprognostic (2.21e-1)" "unprognostic (8.16e-2)" "unprognostic (1.90e-1)" "unprognostic (5.22e-1)" TMEM217 "C6orf128, dJ355M6.2" ENSG00000172738 "Transmembrane protein 217" Q8N7C4 6 37212180-37258155 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 8.4" "Cell type enhanced" "Detected in some" "Astrocytes: 3.6;Bergmann glia: 5.4;Brain inhibitory neurons: 2.7;Choroid plexus epithelial cells: 3.6;Distal convoluted tubule cells: 4.1;Ependymal cells: 5.9;Loop of henle epithelial cells: 7.8;Oligodendrocytes: 3.4;Other brain neurons: 3.1;Papillary tip epithelial cells: 6.9;Podocytes: 5.4;Proximal tubule cells: 8.8;Renal collecting duct intercalated cells: 4.2;Renal collecting duct principal cells: 5.2;Renal connecting tubule cells: 5.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045432, HPA071187" Approved Nucleoli,Cytosol NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 15: Non-specific - Transcription" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 102: Non-specific - Mixed function" Nucleoli Cytosol "HPA045432: , HPA071187: " "unprognostic (1.06e-1)" "unprognostic (2.12e-2)" "unprognostic (3.16e-2)" "unprognostic (2.22e-2)" "unprognostic (1.83e-1)" "unprognostic (9.35e-2)" "unprognostic (2.31e-2)" "unprognostic (1.01e-1)" "unprognostic (2.65e-2)" "unprognostic (4.55e-2)" "unprognostic (9.33e-2)" "unprognostic (4.31e-2)" "unprognostic (2.30e-3)" "unprognostic (4.83e-2)" "unprognostic (3.45e-2)" "unprognostic (7.05e-2)" "potential prognostic favorable (6.17e-5)" "unprognostic (4.14e-1)" "unprognostic (4.87e-2)" "unprognostic (1.91e-1)" "unprognostic (2.05e-3)" TMEM217B ENSG00000286105 "Transmembrane protein 217B" A0A494BZU4 6 37212181-37258144 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 10 "testis: 9.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 59: Leukemia - T-cell receptor" TMEM218 ENSG00000150433 "Transmembrane protein 218" A2RU14 11 125094389-125111763 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ciliopathy, Disease variant, Joubert syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038489 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 67 "Plasma membrane" Cytosol "HPA038489: " "unprognostic (1.60e-1)" "unprognostic (1.52e-1)" "unprognostic (2.43e-2)" "unprognostic (3.02e-3)" "unprognostic (2.94e-1)" "unprognostic (1.96e-2)" "unprognostic (3.46e-1)" "unprognostic (5.29e-3)" "unprognostic (3.55e-1)" "unprognostic (5.97e-3)" "potential prognostic favorable (1.60e-6)" "unprognostic (6.10e-2)" "unprognostic (2.97e-2)" "potential prognostic unfavorable (7.90e-5)" "unprognostic (1.49e-2)" "unprognostic (2.66e-2)" "unprognostic (8.18e-2)" "unprognostic (2.56e-1)" "unprognostic (1.03e-1)" "unprognostic (2.72e-1)" "unprognostic (3.37e-1)" "unprognostic (2.50e-1)" "unprognostic (1.33e-1)" "unprognostic (8.37e-2)" "potential prognostic favorable (9.03e-4)" "unprognostic (1.40e-1)" "unprognostic (1.31e-3)" "unprognostic (9.97e-3)" "unprognostic (4.30e-2)" "unprognostic (2.36e-2)" "unprognostic (1.72e-2)" TMEM219 IGFBP-3R ENSG00000149932 "Transmembrane protein 219" Q86XT9 16 29940885-29973050 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 594.8;Late spermatids: 831.4;Platelets: 514.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059185 Approved NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Ribosome" "Cluster 54: Non-specific - Transcription" "Cluster 47: Platelets - Hemostasis" 2 "HPA059185: " "unprognostic (3.49e-1)" "unprognostic (6.90e-2)" "unprognostic (6.73e-2)" "unprognostic (9.98e-3)" "unprognostic (2.96e-1)" "unprognostic (2.76e-1)" "unprognostic (2.34e-1)" "unprognostic (6.05e-2)" "unprognostic (3.99e-2)" "unprognostic (9.30e-2)" "unprognostic (9.71e-2)" "unprognostic (2.90e-1)" "potential prognostic favorable (4.74e-6)" "unprognostic (3.08e-1)" "unprognostic (3.31e-3)" "unprognostic (4.24e-2)" "unprognostic (5.65e-2)" "unprognostic (1.58e-1)" "unprognostic (1.17e-2)" "unprognostic (1.16e-1)" "unprognostic (1.65e-1)" "unprognostic (1.21e-1)" "unprognostic (2.70e-1)" "unprognostic (3.70e-2)" "unprognostic (1.82e-1)" "unprognostic (3.08e-1)" "unprognostic (1.22e-1)" "unprognostic (1.78e-1)" "unprognostic (2.51e-1)" "unprognostic (2.28e-1)" "unprognostic (2.52e-3)" TMEM220 ENSG00000187824 "Transmembrane protein 220" Q6QAJ8 17 10699015-10730023 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 96.8" "Cell type enhanced" "Detected in many" "Enterocytes: 641.3;Hepatocytes: 234.8;Late primary spermatocytes: 192.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 21.2" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 1: Enterocytes - Absorption and Digestion" 2 "unprognostic (1.31e-2)" "unprognostic (2.73e-1)" "unprognostic (2.77e-1)" "unprognostic (2.73e-1)" "unprognostic (7.33e-2)" "unprognostic (1.22e-1)" "unprognostic (2.31e-2)" "potential prognostic unfavorable (2.74e-5)" "potential prognostic favorable (3.03e-5)" "unprognostic (1.02e-1)" "validated prognostic favorable (4.30e-8)" "validated prognostic favorable (4.29e-4)" "unprognostic (3.62e-2)" "validated prognostic favorable (2.02e-4)" "validated prognostic favorable (4.74e-5)" "unprognostic (4.78e-2)" "unprognostic (2.32e-2)" "unprognostic (1.33e-2)" "unprognostic (2.03e-2)" "unprognostic (1.70e-1)" "unprognostic (1.06e-1)" "potential prognostic favorable (9.10e-4)" "unprognostic (6.14e-3)" "unprognostic (1.60e-1)" "unprognostic (2.06e-1)" "unprognostic (1.34e-1)" "unprognostic (2.11e-2)" "unprognostic (3.56e-1)" "unprognostic (7.89e-3)" "unprognostic (5.46e-3)" "unprognostic (2.18e-1)" TMEM221 ENSG00000188051 "Transmembrane protein 221" A6NGB7 19 17435509-17448668 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "ovary: 7.3;retina: 8.8" "Group enriched" "Detected in some" 4 "Medullary thymic epithelial cells: 33.6;Müller glia: 46.8" "Cell type enhanced" "Detected in many" "MGE interneuron: 14.7" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 5.5;Ovary Serous Cystadenocarcinoma (TCGA): 6.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Stomach - Fibroblasts" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041580, HPA062945" Supported Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 35: RS4;11 - Unknown function" "Cluster 11: Muller glia cells - Retinal homeostasis" "Nuclear membrane" "Nucleoplasm, Cytosol" "HPA041580: , HPA062945: " "unprognostic (5.90e-2)" "potential prognostic unfavorable (3.35e-5)" "unprognostic (1.55e-1)" "unprognostic (2.61e-2)" "unprognostic (2.04e-1)" "unprognostic (1.32e-2)" "unprognostic (7.71e-2)" TMEM222 "C1orf160, DKFZP564D0478" ENSG00000186501 "Transmembrane protein 222" Q9H0R3 1 27322145-27336400 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 102.0;Late spermatids: 137.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016579, HPA059374" Approved Approved "Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 19: Astrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 30 "Plasma membrane, Cytosol" "Cell Junctions" "HPA016579: , HPA059374: " "unprognostic (3.66e-2)" "unprognostic (1.01e-1)" "unprognostic (2.50e-1)" "unprognostic (3.48e-1)" "unprognostic (2.93e-2)" "unprognostic (1.53e-1)" "unprognostic (4.15e-3)" "unprognostic (9.06e-3)" "unprognostic (2.14e-1)" "unprognostic (6.09e-2)" "potential prognostic favorable (2.64e-4)" "unprognostic (7.08e-2)" "potential prognostic favorable (1.48e-5)" "unprognostic (2.52e-2)" "unprognostic (4.66e-3)" "unprognostic (2.38e-1)" "unprognostic (3.81e-1)" "unprognostic (5.96e-2)" "unprognostic (4.35e-1)" "unprognostic (2.64e-2)" "unprognostic (4.11e-1)" "unprognostic (3.43e-2)" "unprognostic (2.70e-2)" "unprognostic (4.30e-2)" "unprognostic (2.98e-1)" "unprognostic (1.88e-3)" "unprognostic (2.65e-1)" "unprognostic (2.43e-1)" "unprognostic (1.38e-1)" "unprognostic (1.06e-1)" "unprognostic (6.44e-3)" TMEM223 "MGC3196, Mrx15" ENSG00000168569 "Transmembrane protein 223" A0PJW6 11 62771629-62792006 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 106.8;Cardiomyocytes: 217.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014504 Approved Approved "Nucleoplasm,Nuclear membrane,Mitochondria" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 70: Non-specific - Protein processing" "Cluster 37: Neurons - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 4 "Nucleoplasm, Nuclear membrane, Mitochondria" "HPA014504: " "unprognostic (3.59e-2)" "unprognostic (1.79e-1)" "unprognostic (1.37e-2)" "unprognostic (2.62e-1)" "unprognostic (8.36e-2)" "unprognostic (2.62e-1)" "unprognostic (9.95e-2)" "unprognostic (2.48e-1)" "unprognostic (2.77e-3)" "unprognostic (3.02e-3)" "unprognostic (3.22e-3)" "unprognostic (8.15e-2)" "unprognostic (1.41e-2)" "unprognostic (8.71e-3)" "unprognostic (4.18e-3)" "potential prognostic unfavorable (4.35e-4)" "unprognostic (8.70e-2)" "unprognostic (4.08e-2)" "unprognostic (2.05e-2)" "unprognostic (3.31e-3)" "unprognostic (2.48e-1)" "unprognostic (4.24e-2)" "unprognostic (2.83e-1)" "unprognostic (2.34e-1)" "unprognostic (1.89e-1)" "unprognostic (4.15e-2)" "unprognostic (1.71e-1)" "unprognostic (2.02e-1)" "unprognostic (9.58e-2)" "unprognostic (8.97e-3)" "unprognostic (3.23e-1)" TMEM225 "PMP22CD, PPP1R154, SPATA47" ENSG00000204300 "Transmembrane protein 225" Q6GV28 11 123882920-123885670 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 205 "testis: 20.5" "Group enriched" "Detected in some" 5 "Early spermatids: 100.8;Late primary spermatocytes: 234.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" TMEM225B ENSG00000244219 "Transmembrane protein 225B" P0DP42 7 99598267-99611045 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 34 "testis: 132.2" "Cell type enriched" "Detected in many" 4 "Late primary spermatocytes: 1154.0" "Cell type enhanced" "Detected in some" "astrocyte: 3.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" "Low region specificity" "Detected in all" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 67: Testis - Mixed function" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 1 "unprognostic (1.85e-2)" "unprognostic (6.71e-3)" "unprognostic (1.71e-1)" "unprognostic (5.22e-2)" "unprognostic (1.10e-1)" "unprognostic (5.71e-2)" "unprognostic (8.64e-2)" "unprognostic (5.28e-2)" "unprognostic (1.44e-1)" "unprognostic (1.14e-1)" "unprognostic (3.33e-1)" "unprognostic (1.11e-1)" "unprognostic (2.37e-2)" "unprognostic (1.90e-1)" "unprognostic (6.95e-2)" TMEM229A ENSG00000234224 "Transmembrane protein 229A" B2RXF0 7 124030921-124033067 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 7.3;intestine: 7.9;testis: 5.0" "Cell type enhanced" "Detected in some" "Astrocytes: 10.2;Cytotrophoblasts: 3.7;Enterocytes: 7.9;Gastric chief cells: 3.3;Gastric progenitor cells: 6.4;Oligodendrocyte progenitor cells: 4.1;Oligodendrocytes: 12.9;Other brain neurons: 3.1;Parietal cells: 7.1;Retinal amacrine cells: 5.5;Retinal ganglion cells: 3.9;Sertoli cells: 8.2" "Cell type enhanced" "Detected in many" "astrocyte: 9.4;oligodendrocyte: 14.4" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 3.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "Bone cancer: 9.8;Neuroblastoma: 11.4" "Colon - Colon enteroendocrine cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056391 Uncertain Approved "Plasma membrane" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 28: Astrocytes - Homeostasis & neuron support" "Plasma membrane" "HPA056391: " "unprognostic (2.62e-2)" "unprognostic (1.01e-1)" "unprognostic (5.39e-3)" "unprognostic (3.57e-2)" TMEM229B "C14orf83, FLJ33387" ENSG00000198133 "Transmembrane protein 229B" Q8NBD8 14 67447084-67533739 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.4" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 89.0;Corticotrophs: 38.9;Epididymal principal cells: 48.2;Gonadotrophs: 38.0;Late spermatids: 47.8;Oligodendrocyte progenitor cells: 50.9;Rod photoreceptor cells: 37.8;Thyrotrophs: 66.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 32.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "skin cancer: 19.3" "Pituitary gland - Thyrotropes, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046562 Approved NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 27: Cerebellum - Synaptic function" "Cluster 37: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" 34 "HPA046562: " "unprognostic (4.38e-3)" "unprognostic (2.67e-3)" "unprognostic (6.95e-2)" "unprognostic (2.47e-1)" "unprognostic (6.26e-2)" "unprognostic (2.76e-1)" "unprognostic (4.92e-2)" "potential prognostic favorable (5.46e-4)" "unprognostic (3.59e-2)" "unprognostic (9.80e-2)" "potential prognostic favorable (5.64e-4)" "unprognostic (1.99e-1)" "unprognostic (7.01e-3)" "unprognostic (2.49e-1)" "unprognostic (1.53e-1)" "unprognostic (1.51e-1)" "unprognostic (1.62e-2)" "unprognostic (2.12e-1)" "unprognostic (1.14e-1)" "unprognostic (4.79e-1)" "unprognostic (1.01e-1)" "unprognostic (9.29e-3)" "unprognostic (5.84e-3)" "unprognostic (2.54e-1)" "unprognostic (9.20e-2)" "unprognostic (1.00e-3)" "unprognostic (1.97e-1)" "unprognostic (1.66e-1)" "unprognostic (1.40e-1)" "unprognostic (5.61e-2)" "unprognostic (3.33e-2)" TMEM230 "C20orf30, HSPC274" ENSG00000089063 "Transmembrane protein 230" Q96A57 20 5068232-5113103 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Parietal cells: 523.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Skin - Endothelial cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009078, HPA061421" Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 76: Non-specific - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 97: Non-specific - Cellular respiration" 7 "Endoplasmic reticulum" "HPA009078: , HPA061421: " "unprognostic (8.97e-2)" "unprognostic (7.76e-3)" "unprognostic (1.38e-1)" "unprognostic (1.76e-1)" "unprognostic (6.96e-3)" "unprognostic (4.72e-2)" "potential prognostic unfavorable (1.34e-5)" "potential prognostic unfavorable (4.84e-4)" "unprognostic (1.36e-2)" "potential prognostic favorable (4.78e-4)" "unprognostic (3.33e-2)" "unprognostic (1.81e-1)" "potential prognostic unfavorable (7.31e-5)" "unprognostic (2.16e-2)" "unprognostic (1.64e-1)" "unprognostic (6.84e-2)" "unprognostic (4.78e-2)" "unprognostic (2.12e-1)" "unprognostic (2.16e-1)" "unprognostic (9.65e-2)" "unprognostic (1.81e-1)" "unprognostic (5.19e-2)" "unprognostic (8.49e-2)" "unprognostic (1.19e-1)" "unprognostic (4.83e-2)" "unprognostic (8.17e-2)" "unprognostic (2.46e-1)" "unprognostic (2.37e-3)" "unprognostic (3.71e-1)" TMEM231 "ALYE870, FLJ22167, JBTS20, MKS11, PRO1886" ENSG00000205084 "Transmembrane protein 231" Q9H6L2 16 75536741-75556289 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome, Meckel syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "choroid plexus: 38.2;fallopian tube: 69.1" "Cell type enriched" "Detected in some" 5 "Ependymal cells: 79.1" "Cell type enriched" "Detected in many" 6 "ependymal cell: 110.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042081 Enhanced Approved "Golgi apparatus,Vesicles,Mid piece" NA NA "Cluster 18: Non-specific - Translation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 34: Ciliated cells - Cilia assembly & function" 36 Vesicles "Golgi apparatus, Mid piece" "HPA042081: " "unprognostic (1.08e-1)" "unprognostic (9.58e-2)" "unprognostic (1.65e-1)" "unprognostic (1.06e-1)" "unprognostic (6.83e-2)" "unprognostic (3.87e-2)" "unprognostic (3.28e-1)" "unprognostic (1.56e-3)" "unprognostic (1.31e-1)" "unprognostic (5.52e-2)" "unprognostic (3.60e-1)" "unprognostic (5.52e-2)" "unprognostic (8.86e-2)" "unprognostic (1.97e-2)" "unprognostic (9.43e-2)" "unprognostic (2.44e-1)" "unprognostic (6.99e-3)" "unprognostic (2.11e-1)" "unprognostic (7.63e-2)" "unprognostic (2.56e-1)" "unprognostic (1.01e-1)" "unprognostic (3.67e-1)" "unprognostic (4.16e-1)" "unprognostic (7.77e-3)" "unprognostic (3.91e-2)" "unprognostic (3.62e-1)" "unprognostic (2.04e-1)" "unprognostic (1.78e-1)" "unprognostic (1.29e-1)" "unprognostic (1.57e-2)" TMEM232 FLJ43080 ENSG00000186952 "Transmembrane protein 232" C9JQI7 5 110289233-110738956 "Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "fallopian tube: 13.5;testis: 15.8" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 1197.0;Endometrial ciliated cells: 929.5;Ependymal cells: 3597.6;Epididymal efferent duct ciliated cells: 590.5;Fallopian tube ciliated cells: 866.2;Respiratory ciliated cells: 1964.7" "Group enriched" "Detected in all" 4 "choroid plexus epithelial cell: 1117.6;ependymal cell: 3784.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA049386 Uncertain NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" "HPA049386: " "unprognostic (1.26e-1)" "unprognostic (3.60e-1)" "unprognostic (1.57e-1)" "potential prognostic favorable (1.24e-9)" "unprognostic (1.00e-3)" "unprognostic (1.39e-1)" "unprognostic (2.20e-2)" "unprognostic (1.73e-1)" "unprognostic (1.89e-3)" "unprognostic (9.33e-3)" "unprognostic (1.26e-3)" "unprognostic (4.21e-1)" TMEM233 "DSPB2, IFITMD2" ENSG00000224982 "Transmembrane protein 233" B4DJY2 12 119593774-119643075 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skeletal muscle: 70.2;tongue: 19.8" "Group enriched" "Detected in many" 5 "Mast cells: 236.6;Myonuclei: 307.5;Myosatellite cells: 113.3" "Cell type enhanced" "Detected in many" "deep-layer corticothalamic and 6b: 35.9;LAMP5-LHX6 and Chandelier: 44.6" "Cancer enhanced" "Detected in some" "Thyroid Carcinoma (TCGA): 18.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bone cancer: 1.5;Brain cancer: 1.5;Sarcoma: 5.7;thyroid cancer: 4.7" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA047506, HPA075435" Uncertain Approved Nucleoplasm NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 51: Neurons - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 46: Skeletal myocytes - Muscle structure & formation" Nucleoplasm "HPA047506: , HPA075435: " "unprognostic (4.43e-2)" "unprognostic (1.32e-3)" "unprognostic (1.32e-1)" "potential prognostic favorable (8.27e-5)" "validated prognostic favorable (1.12e-4)" "validated prognostic favorable (1.32e-6)" "unprognostic (5.61e-2)" "unprognostic (1.71e-3)" "unprognostic (1.97e-1)" "unprognostic (2.14e-1)" "unprognostic (9.84e-2)" TMEM234 "C1orf91, dJ622L5.7, FLJ90779, RP4-622L5" ENSG00000160055 "Transmembrane protein 234" Q8WY98 1 32214472-32222359 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 55.0;Late spermatids: 86.1" "Cell type enhanced" "Detected in all" "ependymal cell: 41.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015049 Uncertain Approved Vesicles NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 21: Testis - Mixed function" "Cluster 17: Choroid plexus - Cilium" "Cluster 37: Non-specific - mRNA processing" "Cluster 97: Non-specific - Cellular respiration" 13 Vesicles "HPA015049: " "unprognostic (1.46e-2)" "unprognostic (8.71e-2)" "unprognostic (1.39e-2)" "unprognostic (5.30e-2)" "unprognostic (1.70e-1)" "unprognostic (3.44e-3)" "unprognostic (3.15e-1)" "unprognostic (2.79e-1)" "unprognostic (1.38e-1)" "unprognostic (1.18e-1)" "unprognostic (5.68e-2)" "unprognostic (1.63e-2)" "potential prognostic unfavorable (1.30e-7)" "unprognostic (7.01e-2)" "unprognostic (5.49e-2)" "unprognostic (1.29e-2)" "unprognostic (2.15e-1)" "unprognostic (1.88e-2)" "unprognostic (9.50e-2)" "unprognostic (2.49e-2)" "unprognostic (3.33e-1)" "unprognostic (7.64e-3)" "unprognostic (9.91e-2)" "unprognostic (1.92e-1)" "unprognostic (3.61e-3)" "unprognostic (8.15e-3)" "unprognostic (4.50e-1)" "unprognostic (1.99e-1)" "unprognostic (6.75e-3)" "unprognostic (2.18e-1)" TMEM235 ENSG00000204278 "Transmembrane protein 235" A6NFC5 17 78231310-78240987 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 14 "brain: 38.2" "Cell type enriched" "Detected in some" 86 "Oligodendrocytes: 173.5" "Group enriched" "Detected in many" 46 "committed oligodendrocyte precursor: 112.1;oligodendrocyte: 174.8" "Cancer enriched" "Detected in single" 17 "Glioblastoma Multiforme (TCGA): 2.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA053939 Uncertain NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 80: Oligodendrocytes - Myelination" "HPA053939: " "unprognostic (1.45e-1)" "unprognostic (2.50e-1)" TMEM236 "bA162I21.2, bA16O1.2, FAM23A, FAM23B" ENSG00000148483 "Transmembrane protein 236" Q5W0B7 10 17752201-17800868 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "intestine: 31.5" "Cell type enhanced" "Detected in many" "Breast lactating cells: 114.2;Colonocytes: 141.9;Enteric stem cells: 44.1;Enteric transient amplifying cells: 64.0;Enterocytes: 239.2;Goblet cells: 99.4;Neuroendocrine cells: 44.3;Pancreatic islet cells: 128.9" "Cell type enriched" "Detected in some" 4 "central nervous system macrophage: 9.0" "Cancer enhanced" "Detected in some" "Rectum Adenocarcinoma (TCGA): 2.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Leukemia: 1.3;Rhabdoid: 1.6" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Lung - Macrophages, Minor Salivary Gland - Macrophages, Prostate - Macrophages, Skin - Macrophages, Thyroid gland - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA045096 Enhanced NA NA "Cluster 77: Intestine - Digestion" "Cluster 9: Non-specific - Receptor signaling" "Cluster 6: Leukemia - Signal transduction" "Cluster 1: Enterocytes - Absorption and Digestion" 4 "HPA045096: " "unprognostic (3.93e-2)" "unprognostic (5.96e-2)" "unprognostic (1.85e-2)" "unprognostic (1.89e-1)" TMEM237 "ALS2CR4, JBTS14" ENSG00000155755 "Transmembrane protein 237" Q96Q45 2 201620184-201643570 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cilium biogenesis/degradation" "Ciliopathy, Joubert syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "retina: 71.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 77.7;Breast myoepithelial cells: 102.5;Rod photoreceptor cells: 181.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052596, HPA054732" Enhanced Approved "Nuclear speckles,Plasma membrane,Microtubules,Cytokinetic bridge,Primary cilium,Primary cilium transition zone" Yes NA "Cluster 42: Retina - Visual perception" "Cluster 14: Neurons - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 79: Photoreceptor cells - Phototransduction" 9 "Nuclear speckles, Plasma membrane, Microtubules, Primary cilium" "Cytokinetic bridge, Primary cilium transition zone" "HPA052596: , HPA054732: " "unprognostic (1.24e-1)" "unprognostic (8.96e-3)" "unprognostic (2.99e-2)" "unprognostic (1.33e-1)" "unprognostic (1.70e-1)" "unprognostic (2.59e-2)" "unprognostic (2.84e-2)" "unprognostic (8.17e-2)" "unprognostic (1.30e-1)" "unprognostic (5.23e-2)" "unprognostic (9.73e-2)" "unprognostic (7.39e-3)" "validated prognostic unfavorable (3.18e-5)" "validated prognostic unfavorable (1.55e-5)" "unprognostic (3.42e-1)" "unprognostic (3.35e-2)" "unprognostic (5.90e-2)" "unprognostic (1.11e-1)" "unprognostic (7.31e-2)" "unprognostic (3.11e-1)" "unprognostic (5.73e-2)" "unprognostic (9.20e-3)" "unprognostic (4.00e-1)" "unprognostic (2.93e-2)" "unprognostic (1.68e-3)" "unprognostic (4.08e-2)" "unprognostic (1.32e-1)" "unprognostic (2.52e-1)" "unprognostic (3.58e-1)" "unprognostic (1.30e-1)" TMEM238 ENSG00000233493 "Transmembrane protein 238" C9JI98 19 55379244-55384292 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 20.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 177.8;Fallopian secretory cells: 284.0;Pancreatic acinar cells: 179.7;Prostatic club cells: 166.8;Respiratory deuterosomal cells: 220.8;Respiratory secretory cells: 186.3;Transitional alveolar cells: 149.0;Urothelial cells: 133.8" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 9.5;leukocyte: 16.2" "Group enriched" "Detected in all" 4 "Ovary Serous Cystadenocarcinoma (TCGA): 107.0;Stomach Adenocarcinoma (TCGA): 109.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enterocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 60: Stomach - Digestion" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 81: Alveolar cells - Lung function" "unprognostic (3.95e-3)" "unprognostic (5.82e-2)" "unprognostic (4.92e-2)" "unprognostic (3.39e-2)" "unprognostic (1.53e-1)" "unprognostic (1.11e-2)" "unprognostic (8.78e-2)" "potential prognostic favorable (1.47e-5)" "unprognostic (3.10e-3)" "unprognostic (3.82e-3)" "unprognostic (2.55e-1)" "unprognostic (1.29e-1)" "unprognostic (1.92e-1)" "unprognostic (1.07e-1)" "unprognostic (1.92e-1)" "unprognostic (5.87e-2)" "unprognostic (1.42e-1)" "unprognostic (5.96e-2)" "unprognostic (1.45e-1)" "unprognostic (9.45e-2)" "unprognostic (1.37e-1)" "unprognostic (7.70e-2)" "unprognostic (8.44e-2)" "unprognostic (5.82e-3)" "unprognostic (3.46e-1)" "unprognostic (2.04e-2)" "unprognostic (1.02e-1)" TMEM238L "FORCP, LINC00675" ENSG00000263429 "Transmembrane protein 238 like" A6NJY4 17 10794908-10804099 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at transcript level" "Group enriched" "Detected in some" 7 "intestine: 35.1;stomach 1: 42.6;urinary bladder: 20.2" "Group enriched" "Detected in some" 6 "Papillary tip epithelial cells: 20.1;Renal collecting duct principal cells: 21.1" "Cell type enhanced" "Detected in some" "astrocyte: 2.8" "Cancer enhanced" "Detected in some" "Colon Adenocarcinoma (TCGA): 17.9;Rectum Adenocarcinoma (TCGA): 16.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Bile duct cancer: 2.7;colorectal cancer: 7.1;Gastric cancer: 3.0" "Colon - Colon enterocytes" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 17: Intestine - Digestion" "Cluster 19: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 1 "unprognostic (1.46e-2)" "unprognostic (3.29e-1)" "unprognostic (1.17e-1)" "potential prognostic favorable (2.25e-4)" "unprognostic (9.15e-2)" "unprognostic (1.52e-3)" "unprognostic (9.77e-3)" "unprognostic (7.37e-3)" "unprognostic (1.84e-1)" TMEM239 ENSG00000198326 "Transmembrane protein 239" Q8WW34 20 2816302-2820284 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 43 "testis: 36.0" "Cell type enriched" "Detected in some" 7 "Late spermatids: 183.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 10 TMEM240 "C1orf70, SCA21" ENSG00000205090 "Transmembrane protein 240" Q5SV17 1 1534778-1540624 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Intellectual disability, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 61.2" "Cell type enhanced" "Detected in many" "Astrocytes: 14.7;Bergmann glia: 19.2;Brain excitatory neurons: 29.4;Brain inhibitory neurons: 27.5;Hepatic stellate cells: 19.4;Oligodendrocyte progenitor cells: 16.5;Other brain neurons: 22.1;Retinal amacrine cells: 23.7;Retinal bipolar cells: 10.4;Retinal horizontal cells: 24.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 12.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066721 Supported NA NA "Cluster 65: Brain - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 98: Neurons - Neurotransmission & signaling" "HPA066721: " "unprognostic (4.01e-2)" "unprognostic (1.80e-1)" "unprognostic (2.66e-2)" "unprognostic (2.38e-3)" "unprognostic (1.28e-1)" "unprognostic (2.93e-1)" "potential prognostic favorable (5.75e-4)" "unprognostic (5.34e-2)" "unprognostic (1.41e-3)" "unprognostic (1.06e-1)" "unprognostic (3.61e-2)" "unprognostic (2.98e-1)" "unprognostic (1.42e-3)" "unprognostic (6.20e-2)" "unprognostic (2.93e-1)" "unprognostic (1.16e-3)" "unprognostic (1.32e-1)" "unprognostic (2.43e-1)" "unprognostic (3.08e-3)" "unprognostic (8.40e-2)" "unprognostic (3.65e-2)" "potential prognostic unfavorable (3.16e-4)" "unprognostic (2.73e-1)" "unprognostic (3.61e-2)" "unprognostic (1.12e-1)" TMEM241 "C18orf45, FLJ44259, MGC11386" ENSG00000134490 "Transmembrane protein 241" Q24JQ0 18 23197144-23437961 "Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 190.2;Endometrial glandular cells: 389.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 6.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029489, HPA059922" Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 51: Neurons - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 51: Secretory epithelial cells - Mixed function" 1 "Golgi apparatus" Vesicles "HPA029489: , HPA059922: " "unprognostic (7.23e-3)" "unprognostic (1.97e-2)" "unprognostic (3.70e-2)" "unprognostic (4.21e-2)" "unprognostic (2.73e-1)" "unprognostic (5.03e-2)" "unprognostic (5.20e-3)" "unprognostic (2.94e-1)" "potential prognostic favorable (5.58e-6)" "unprognostic (2.54e-2)" "unprognostic (1.03e-1)" "potential prognostic unfavorable (3.87e-4)" "unprognostic (5.27e-2)" "unprognostic (6.35e-2)" "unprognostic (1.63e-2)" "unprognostic (5.85e-2)" "unprognostic (1.39e-1)" "unprognostic (3.43e-2)" "potential prognostic unfavorable (4.70e-5)" "unprognostic (6.69e-2)" "unprognostic (1.06e-1)" "unprognostic (3.54e-1)" "unprognostic (3.94e-1)" "unprognostic (4.51e-2)" "unprognostic (5.47e-2)" "unprognostic (7.33e-2)" "unprognostic (7.91e-2)" TMEM242 "BM033, C6orf35" ENSG00000215712 "Transmembrane protein 242" Q9NWH2 6 157289025-157323601 "Essential proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025764 Approved NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 34: Non-specific - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 97: Non-specific - Cellular respiration" 33 "HPA025764: " "unprognostic (2.00e-1)" "potential prognostic unfavorable (8.77e-6)" "unprognostic (1.04e-2)" "unprognostic (1.10e-1)" "unprognostic (2.34e-1)" "unprognostic (1.88e-2)" "unprognostic (5.10e-3)" "potential prognostic unfavorable (2.92e-5)" "unprognostic (2.96e-1)" "potential prognostic favorable (1.79e-5)" "unprognostic (6.90e-3)" "unprognostic (2.22e-1)" "unprognostic (1.08e-1)" "unprognostic (3.02e-2)" "unprognostic (1.04e-1)" "unprognostic (1.96e-1)" "unprognostic (3.25e-1)" "potential prognostic unfavorable (6.43e-4)" "unprognostic (1.07e-1)" "unprognostic (1.32e-1)" "unprognostic (2.22e-2)" "unprognostic (1.99e-1)" "unprognostic (3.78e-2)" "unprognostic (1.42e-1)" "unprognostic (3.51e-1)" "unprognostic (6.62e-2)" "unprognostic (4.07e-2)" "unprognostic (2.18e-1)" "unprognostic (6.24e-3)" TMEM243 "C7orf23, MGC4175, MM-TRAG" ENSG00000135185 "Transmembrane protein 243" Q9BU79 7 87196160-87220587 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 225.1;B-cells: 240.9;Late primary spermatocytes: 206.9;Oocytes: 469.7;Plasma cells: 208.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014918 Uncertain NA Yes "Cluster 24: Non-specific - Transcription" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 21: Non-specific - Metabolism" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 37 "HPA014918: " "potential prognostic favorable (3.18e-5)" "unprognostic (2.20e-2)" "unprognostic (1.44e-1)" "unprognostic (5.77e-2)" "unprognostic (1.99e-1)" "unprognostic (4.21e-3)" "unprognostic (2.88e-1)" "unprognostic (3.04e-1)" "unprognostic (8.94e-2)" "potential prognostic favorable (9.08e-7)" "unprognostic (2.84e-1)" "unprognostic (2.34e-1)" "unprognostic (1.46e-2)" "unprognostic (4.39e-3)" "unprognostic (7.09e-2)" "unprognostic (2.55e-1)" "unprognostic (4.95e-1)" "unprognostic (9.38e-3)" "unprognostic (1.76e-1)" "unprognostic (6.65e-2)" "unprognostic (2.44e-1)" "unprognostic (3.08e-2)" "unprognostic (9.88e-2)" "unprognostic (4.26e-1)" "unprognostic (1.50e-2)" "unprognostic (5.27e-3)" "unprognostic (1.40e-1)" "unprognostic (5.03e-2)" "unprognostic (1.11e-1)" TMEM244 "bA174C7.4, C6orf191" ENSG00000203756 "Transmembrane protein 244" Q5VVB8 6 129831244-129861547 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 36 "retina: 59.4" "Group enriched" "Detected in some" 4 "Cone photoreceptor cells: 109.7;Rod photoreceptor cells: 219.3" "Cell type enhanced" "Detected in many" "deep-layer intratelencephalic: 23.2;hippocampal dentate gyrus: 52.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "memory CD4 T-cell: 1.4;T-reg: 1.6" "Lineage enriched" "Detected in single" 9 "T-cells: 1.6" "Cancer enriched" "Detected in single" 5 "Brain cancer: 4.3" "Pituitary gland - Lactotropes" "Not detected" "Not detected" NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 42: Retina - Visual perception" "Cluster 51: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 79: Photoreceptor cells - Phototransduction" TMEM245 "C9orf5, CG-2" ENSG00000106771 "Transmembrane protein 245" Q9H330 9 109015135-109119947 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adrenal cortex cells: 635.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023892 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 18: Adrenal cortex cells - Steroidogensis" "Plasma membrane, Cytosol" "HPA023892: " "unprognostic (1.01e-1)" "unprognostic (4.75e-3)" "unprognostic (1.47e-2)" "unprognostic (4.24e-1)" "potential prognostic unfavorable (3.48e-4)" "unprognostic (1.43e-1)" "unprognostic (2.23e-1)" "unprognostic (7.58e-2)" "unprognostic (4.39e-2)" "validated prognostic favorable (4.12e-9)" "validated prognostic favorable (6.48e-5)" "unprognostic (7.65e-2)" "unprognostic (1.56e-1)" "unprognostic (1.38e-1)" "unprognostic (3.89e-1)" "unprognostic (8.42e-2)" "unprognostic (1.11e-1)" "unprognostic (6.97e-2)" "unprognostic (1.02e-2)" "unprognostic (1.14e-1)" "unprognostic (4.46e-1)" "unprognostic (3.27e-1)" "unprognostic (1.04e-1)" "unprognostic (1.89e-1)" "unprognostic (1.63e-2)" "unprognostic (1.49e-1)" "unprognostic (1.31e-1)" "unprognostic (3.65e-1)" "unprognostic (1.80e-1)" TMEM247 ENSG00000284701 "Transmembrane protein 247" A6NEH6 2 46479565-46484425 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 32 "testis: 46.4" "Group enriched" "Detected in some" 12 "Early spermatids: 418.7;Late primary spermatocytes: 219.6;Late spermatids: 448.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Myeloma: 1.3" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" HPA079482 Enhanced NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" "HPA079482: " TMEM248 "C7orf42, FLJ10099, FLJ13090" ENSG00000106609 "Transmembrane protein 248" Q9NWD8 7 66921225-66958551 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 271.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016495 Uncertain Approved Vesicles NA NA 17000 "Cluster 22: Eosinophils - Transcription" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 8: Non-specific - Secretory pathway" 21 Vesicles "HPA016495: " "unprognostic (2.61e-2)" "unprognostic (2.21e-1)" "unprognostic (1.08e-2)" "unprognostic (4.35e-2)" "unprognostic (2.08e-1)" "unprognostic (2.58e-2)" "potential prognostic unfavorable (1.25e-5)" "unprognostic (2.09e-1)" "unprognostic (3.56e-2)" "unprognostic (1.12e-3)" "unprognostic (8.26e-2)" "unprognostic (3.57e-2)" "unprognostic (1.53e-2)" "unprognostic (2.22e-1)" "unprognostic (9.51e-2)" "unprognostic (1.25e-2)" "unprognostic (1.77e-2)" "unprognostic (2.06e-2)" "unprognostic (2.07e-2)" "unprognostic (6.65e-2)" "unprognostic (1.04e-1)" "unprognostic (1.98e-1)" "unprognostic (8.50e-2)" "potential prognostic unfavorable (8.36e-4)" "unprognostic (1.66e-2)" "unprognostic (4.08e-1)" "unprognostic (1.95e-1)" "unprognostic (2.33e-1)" "unprognostic (4.35e-1)" TMEM249 C8orfK29 ENSG00000261587 "Transmembrane protein 249" Q2WGJ8 8 144352219-144354954 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "testis: 26.3" "Cell type enhanced" "Detected in some" "Astrocytes: 3.3;Bergmann glia: 1.7;Brain excitatory neurons: 3.7;Brain inhibitory neurons: 3.1;Early spermatids: 3.0;Late primary spermatocytes: 3.2;Late spermatids: 6.9;Oligodendrocyte progenitor cells: 1.8;Other brain neurons: 2.0" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Rhabdoid: 3.0" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA078901 Approved NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 15: Non-specific - Transcription" "Cluster 3: Rhabdoid - Membrane components" "Cluster 2: Cerebellar granular cells - Neuronal signaling" "HPA078901: " TMEM25 FLJ14399 ENSG00000149582 "Transmembrane protein 25" Q86YD3 11 118531041-118547280 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 143.1;Oocytes: 69.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012163, HPA051562" Approved Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" "No annotated function" NA NA 630000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 64: Non-specific - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 24: Non-specific - Unknown function" "Cluster 1: Enterocytes - Absorption and Digestion" 4 "Golgi apparatus, Vesicles" "HPA012163: , HPA051562: " "unprognostic (1.27e-1)" "unprognostic (7.17e-2)" "unprognostic (2.74e-1)" "unprognostic (1.92e-2)" "unprognostic (1.36e-1)" "unprognostic (1.82e-2)" "unprognostic (3.12e-1)" "unprognostic (2.60e-3)" "unprognostic (4.22e-2)" "unprognostic (1.26e-3)" "validated prognostic favorable (3.53e-9)" "validated prognostic favorable (2.95e-5)" "potential prognostic favorable (1.80e-10)" "unprognostic (1.58e-1)" "unprognostic (3.39e-3)" "unprognostic (1.60e-2)" "unprognostic (1.15e-2)" "unprognostic (1.94e-1)" "unprognostic (3.25e-1)" "unprognostic (7.65e-2)" "unprognostic (2.36e-2)" "unprognostic (2.38e-2)" "unprognostic (4.69e-2)" "unprognostic (1.57e-1)" "unprognostic (8.64e-2)" "unprognostic (8.39e-2)" "unprognostic (2.59e-1)" "unprognostic (1.76e-1)" "unprognostic (4.18e-1)" "unprognostic (2.07e-1)" "unprognostic (3.38e-1)" TMEM250 "bA83N9.1, C9orf69" ENSG00000238227 "Transmembrane protein 250" H0YL14 9 136114581-136118875 "Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Tuft cells: 46.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066070 Supported Supported Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 24: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 17: Non-specific - RNA processing" Nucleoplasm "HPA066070: " "unprognostic (1.62e-2)" "unprognostic (1.11e-2)" "unprognostic (1.91e-1)" "unprognostic (2.10e-2)" "unprognostic (5.79e-3)" "unprognostic (2.18e-1)" "unprognostic (5.53e-2)" "unprognostic (1.71e-1)" "unprognostic (5.24e-2)" "unprognostic (4.06e-2)" "unprognostic (2.05e-1)" "unprognostic (2.79e-1)" "unprognostic (5.25e-2)" "unprognostic (3.33e-3)" "unprognostic (1.05e-1)" "unprognostic (9.81e-2)" "unprognostic (2.16e-1)" "unprognostic (9.98e-2)" "unprognostic (4.02e-2)" "unprognostic (1.87e-1)" "unprognostic (1.71e-1)" "unprognostic (1.03e-2)" "unprognostic (2.25e-1)" "unprognostic (4.01e-2)" "unprognostic (2.90e-1)" "unprognostic (4.55e-2)" "unprognostic (2.01e-1)" "unprognostic (2.45e-1)" "potential prognostic favorable (1.62e-4)" TMEM251 "C14orf109, DKFZP564F1123" ENSG00000153485 "Transmembrane protein 251" Q8N6I4 14 93184951-93188463 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Host-virus interaction" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Gastric chief cells: 2.2;Medullary thymic epithelial cells: 2.4;Melanocytes: 2.2;Parietal cells: 1.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Macrophages, Minor Salivary Gland - Smooth muscle cells, Prostate - Prostate glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048559 Uncertain Approved "Golgi apparatus,Cell Junctions" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 97: Non-specific - Cellular respiration" "Cell Junctions" "Golgi apparatus" "HPA048559: " "unprognostic (6.81e-2)" "unprognostic (2.18e-1)" "unprognostic (7.90e-2)" "unprognostic (7.94e-2)" "unprognostic (1.31e-3)" "unprognostic (1.36e-1)" "unprognostic (1.37e-2)" "unprognostic (2.30e-2)" "unprognostic (1.89e-1)" "potential prognostic favorable (1.24e-4)" "unprognostic (1.14e-2)" "unprognostic (2.22e-2)" "potential prognostic unfavorable (1.63e-7)" "unprognostic (2.04e-2)" "unprognostic (1.87e-1)" "unprognostic (1.22e-2)" "potential prognostic favorable (6.33e-4)" "unprognostic (1.46e-2)" "unprognostic (1.34e-1)" "unprognostic (3.35e-3)" "unprognostic (3.35e-1)" "unprognostic (1.64e-1)" "unprognostic (7.03e-3)" "unprognostic (1.86e-3)" "unprognostic (2.76e-1)" "unprognostic (1.70e-1)" "unprognostic (1.12e-1)" "unprognostic (3.19e-2)" "unprognostic (8.21e-2)" TMEM252 "C9orf71, MGC34760" ENSG00000181778 "Transmembrane protein 252" Q8N6L7 9 68536580-68540883 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 20.7;kidney: 33.3" "Cell type enriched" "Detected in some" 4 "Enterocytes: 56.9" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 7 "Kidney Renal Papillary Cell Carcinoma (TCGA): 136.9" "Region enhanced" "Detected in single" "cerebellum: 2.6" "Immune cell enriched" "Detected in single" 8 "neutrophil: 4.1" "Lineage enriched" "Detected in single" 40 "granulocytes: 4.1" "Group enriched" "Detected in some" 7 "ovarian cancer: 1.0;Uterine cancer: 2.3" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Prostate - Smooth muscle cells, Skin - Fibroblasts_2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045272, HPA079457" Enhanced Approved "Nuclear speckles,Plasma membrane,Primary cilium,Basal body" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 72: Kidney - Transmembrane transport" "Cluster 35: Non-specific - DNA binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 1: Enterocytes - Absorption and Digestion" 5 "Nuclear speckles, Plasma membrane" "Primary cilium, Basal body" "HPA045272: , HPA079457: " "unprognostic (1.82e-2)" "unprognostic (2.25e-1)" "validated prognostic favorable (1.15e-7)" "validated prognostic favorable (3.24e-4)" "unprognostic (2.80e-3)" "unprognostic (2.39e-2)" "unprognostic (6.07e-3)" "unprognostic (7.28e-3)" "unprognostic (1.15e-1)" "unprognostic (1.96e-1)" TMEM253 "C14orf176, C14orf95, NCRNA00220" ENSG00000232070 "Transmembrane protein 253" P0C7T8 14 21098811-21103724 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "intestine: 91.3" "Cell type enriched" "Detected in some" 4 "Enterocytes: 184.5" "Cell type enhanced" "Detected in some" "ependymal cell: 1.9" "Cancer enhanced" "Detected in many" "Stomach Adenocarcinoma (TCGA): 7.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 3.3" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" "HPA052329, HPA065092" Enhanced NA NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 1: Enterocytes - Absorption and Digestion" "HPA052329: , HPA065092: " "unprognostic (2.61e-2)" "unprognostic (4.66e-3)" "unprognostic (4.43e-2)" "unprognostic (4.60e-2)" "unprognostic (9.00e-2)" "unprognostic (2.50e-1)" "unprognostic (1.81e-2)" "unprognostic (2.22e-1)" "unprognostic (2.92e-1)" "unprognostic (1.07e-1)" "unprognostic (3.44e-1)" "unprognostic (1.57e-1)" "unprognostic (4.68e-2)" TMEM254 "bA369J21.6, C10orf57, FLJ13263" ENSG00000133678 "Transmembrane protein 254" Q8TBM7 10 80078646-80092557 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ependymal cells: 93.9;Epididymal principal cells: 93.8;Esophageal apical cells: 167.3;Esophageal suprabasal cells: 90.8;Respiratory ciliated cells: 107.6" "Cell type enhanced" "Detected in all" "ependymal cell: 104.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Prostate - Prostate glandular cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029105, HPA072613" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 58: Skin - Keratinization" "Cluster 39: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 85: Squamous epithelial cells - Keratinization" 35 "Plasma membrane" Nucleoplasm "HPA029105: , HPA072613: " "unprognostic (9.04e-2)" "unprognostic (1.98e-3)" "unprognostic (5.85e-2)" "unprognostic (3.84e-2)" "unprognostic (1.19e-2)" "unprognostic (2.92e-1)" "unprognostic (2.22e-2)" "unprognostic (1.92e-1)" "unprognostic (3.87e-2)" "potential prognostic favorable (2.31e-4)" "unprognostic (1.62e-1)" "unprognostic (8.32e-2)" "unprognostic (1.61e-1)" "unprognostic (7.48e-2)" "unprognostic (3.10e-1)" "unprognostic (9.28e-2)" "unprognostic (2.39e-1)" "unprognostic (4.13e-2)" "unprognostic (1.95e-1)" "unprognostic (2.02e-2)" "unprognostic (2.97e-1)" "unprognostic (3.19e-1)" "unprognostic (1.17e-2)" "unprognostic (8.77e-3)" "unprognostic (8.44e-2)" "unprognostic (2.71e-1)" "unprognostic (3.45e-1)" "unprognostic (6.66e-3)" "unprognostic (1.33e-1)" TMEM255A "FAM70A, FLJ20716" ENSG00000125355 "Transmembrane protein 255A" Q5JRV8 X 120258650-120311556 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.9;ovary: 16.4" "Cell type enhanced" "Detected in some" "Bergmann glia: 16.6;Corticotrophs: 35.3;Fibro-adipogenic progenitors: 14.3;Mesothelial cells: 14.6;Microglia: 12.8;Myosatellite cells: 15.7;Oligodendrocyte progenitor cells: 48.2;Other brain neurons: 37.2;Pituitary stem cells: 30.3;Renal collecting duct intercalated cells: 29.0;Retinal amacrine cells: 26.2;Schwann cells: 17.6" "Cell type enhanced" "Detected in many" "LAMP5-LHX6 and Chandelier: 105.4;oligodendrocyte precursor cell: 55.1" "Group enriched" "Detected in many" 4 "Glioblastoma Multiforme (TCGA): 40.9;Kidney Chromophobe (TCGA): 103.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.8" "Lineage enriched" "Detected in single" 9 "T-cells: 2.8" "Cancer enhanced" "Detected in many" "Myeloma: 13.1;skin cancer: 11.7" "Minor Salivary Gland - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048470 Approved Uncertain "Nucleoplasm,Nuclear bodies" No No "Cluster 24: Non-specific - Transcription" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 109: Neurons - Neuronal signaling" "Nucleoplasm, Nuclear bodies" "HPA048470: " "unprognostic (2.51e-2)" "unprognostic (1.21e-1)" "unprognostic (3.48e-1)" "unprognostic (1.80e-1)" "unprognostic (1.49e-1)" "unprognostic (1.12e-1)" "unprognostic (5.52e-2)" "unprognostic (1.51e-1)" "unprognostic (6.75e-2)" "unprognostic (2.25e-1)" "unprognostic (4.31e-2)" "unprognostic (1.28e-1)" "unprognostic (9.34e-2)" "unprognostic (1.19e-1)" "unprognostic (1.91e-1)" "unprognostic (1.14e-2)" "unprognostic (2.41e-1)" "unprognostic (1.34e-1)" "unprognostic (2.25e-1)" "unprognostic (7.83e-2)" "unprognostic (3.80e-1)" "unprognostic (3.01e-2)" TMEM255B "FAM70B, MGC20579" ENSG00000184497 "Transmembrane protein 255B" Q8WV15 13 113759226-113816995 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 20.4;Hofbauer cells: 21.3;Kupffer cells: 19.5;Lymphatic endothelial cells: 110.3;Macrophages: 21.8;Mast cells: 45.0;Microglia: 23.1;Vascular endothelial cells: 101.2" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 32.0;endothelial cell: 16.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "basophil: 31.2" "Lineage enriched" "Detected in many" 6 "granulocytes: 31.2" "Low cancer specificity" "Detected in many" "Adrenal gland - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Pancreas - Endothelial cells, Pituitary gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA043334 Approved Approved Nucleoplasm NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 8: Immune cells - Immune response" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 7 Nucleoplasm "HPA043334: " "unprognostic (7.04e-2)" "unprognostic (1.95e-1)" "unprognostic (7.95e-2)" "unprognostic (2.32e-1)" "unprognostic (2.12e-1)" "unprognostic (2.97e-2)" "unprognostic (1.26e-1)" "unprognostic (2.05e-1)" "unprognostic (8.95e-2)" "unprognostic (3.95e-3)" "unprognostic (1.45e-3)" "unprognostic (3.49e-2)" "unprognostic (1.42e-1)" "unprognostic (2.25e-1)" "unprognostic (2.29e-1)" "unprognostic (3.17e-3)" "unprognostic (2.45e-2)" "unprognostic (1.29e-2)" "unprognostic (3.65e-1)" "unprognostic (9.25e-2)" "unprognostic (1.16e-2)" "unprognostic (1.30e-1)" "unprognostic (1.07e-1)" "unprognostic (3.40e-2)" "unprognostic (2.29e-1)" "unprognostic (8.20e-3)" "unprognostic (1.38e-1)" "unprognostic (3.42e-1)" "unprognostic (5.01e-2)" TMEM256 "C17orf61, MGC40107" ENSG00000205544 "Transmembrane protein 256" Q8N2U0 17 7402975-7404097 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 660.1;Epididymal efferent duct absorptive cells: 256.5;Epididymal principal cells: 226.1;Gastric chief cells: 298.1;Hepatocytes: 355.5;Oocytes: 257.9;Parietal cells: 401.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062732 Approved Vesicles NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 1: Enterocytes - Absorption and Digestion" Vesicles "HPA062732: " "unprognostic (2.20e-3)" "unprognostic (7.00e-2)" "unprognostic (8.69e-2)" "unprognostic (2.16e-1)" "unprognostic (1.42e-2)" "unprognostic (5.21e-2)" "unprognostic (2.54e-1)" "unprognostic (2.03e-3)" "unprognostic (6.50e-2)" "unprognostic (2.07e-1)" "unprognostic (9.80e-2)" "unprognostic (1.05e-3)" "unprognostic (2.10e-2)" "unprognostic (2.90e-2)" "unprognostic (2.09e-1)" "unprognostic (2.30e-1)" "unprognostic (2.52e-1)" "unprognostic (1.67e-2)" "unprognostic (5.79e-2)" "unprognostic (6.28e-2)" "unprognostic (4.58e-2)" "unprognostic (1.39e-1)" "unprognostic (1.13e-1)" "unprognostic (1.20e-1)" "unprognostic (6.05e-2)" "unprognostic (2.17e-2)" "unprognostic (1.96e-1)" "unprognostic (1.65e-1)" "unprognostic (9.46e-2)" TMEM258 "C11orf10, Kud, Kuduk" ENSG00000134825 "Transmembrane protein 258" P61165 11 61768501-61792802 "Essential proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epicardial cells: 1100.7;Epididymal principal cells: 1390.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044602 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 70: Non-specific - Protein processing" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 67: Plasma cells - Plasma cell differentiation" 6 Cytosol "Plasma membrane" "HPA044602: " "unprognostic (9.30e-3)" "unprognostic (5.42e-2)" "unprognostic (3.75e-2)" "unprognostic (2.52e-1)" "unprognostic (5.04e-2)" "unprognostic (2.80e-2)" "unprognostic (1.97e-1)" "unprognostic (3.60e-3)" "unprognostic (1.57e-1)" "unprognostic (2.22e-1)" "potential prognostic unfavorable (1.75e-4)" "unprognostic (2.74e-2)" "potential prognostic unfavorable (7.31e-4)" "unprognostic (7.90e-3)" "unprognostic (9.71e-3)" "unprognostic (4.70e-2)" "unprognostic (1.34e-1)" "unprognostic (1.78e-3)" "unprognostic (1.78e-2)" "potential prognostic unfavorable (2.18e-5)" "unprognostic (2.56e-1)" "unprognostic (1.55e-2)" "unprognostic (4.96e-1)" "unprognostic (1.98e-1)" "unprognostic (2.47e-2)" "unprognostic (1.71e-1)" "unprognostic (1.78e-1)" "unprognostic (1.03e-1)" "unprognostic (1.26e-1)" TMEM259 "ASBABP1, C19orf6, MBRL, MGC4022" ENSG00000182087 "Transmembrane protein 259" Q4ZIN3 19 1009648-1021179 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042669, HPA054801" Approved Approved "Nuclear speckles,Endoplasmic reticulum" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 18: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 20: Non-specific - Transcription regulation" 12 "Endoplasmic reticulum" "Nuclear speckles" "HPA042669: , HPA054801: " "unprognostic (4.15e-2)" "unprognostic (1.92e-2)" "unprognostic (7.69e-3)" "unprognostic (1.25e-1)" "unprognostic (1.13e-1)" "unprognostic (2.03e-1)" "unprognostic (1.64e-1)" "unprognostic (1.09e-1)" "unprognostic (2.56e-1)" "unprognostic (1.66e-2)" "unprognostic (3.17e-2)" "unprognostic (1.17e-1)" "unprognostic (4.49e-2)" "unprognostic (5.47e-2)" "unprognostic (2.31e-1)" "unprognostic (4.47e-2)" "unprognostic (5.75e-3)" "unprognostic (1.07e-1)" "unprognostic (5.48e-3)" "unprognostic (1.81e-2)" "unprognostic (1.93e-3)" "unprognostic (2.60e-2)" "unprognostic (1.60e-2)" "unprognostic (1.33e-3)" "unprognostic (2.31e-1)" "unprognostic (7.01e-2)" "unprognostic (1.58e-1)" "unprognostic (1.32e-1)" "unprognostic (3.31e-2)" TMEM26 "Em:AC068892.1, MGC35010" ENSG00000196932 "Transmembrane protein 26" Q6ZUK4 10 61406642-61453381 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 8.3" "Cell type enhanced" "Detected in some" "Breast hormone-responsive cells: 29.6;Endometrial stromal cells: 13.2;Kupffer cells: 166.0;Macrophages: 21.9;Mesothelial cells: 12.1;Oligodendrocytes: 13.7;Pituitary stem cells: 13.5;Prostatic glandular cells: 13.6;Sertoli cells: 63.0" "Cell type enhanced" "Detected in many" "thalamic excitatory: 38.1" "Cancer enhanced" "Detected in some" "Breast Invasive Carcinoma (TCGA): 5.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.5;Rhabdoid: 2.0" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Pituitary gland - Fibroblasts" "Region enhanced" "Detected in some" "hypothalamus: 2.3" "Low region specificity" "Detected in all" HPA064550 Uncertain NA NA "Cluster 66: Lymphoid tissue - Immune response" "Cluster 38: Sub-cortical - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" "HPA064550: " "unprognostic (5.24e-3)" "unprognostic (3.39e-1)" "unprognostic (3.45e-2)" "unprognostic (2.61e-2)" "unprognostic (1.11e-2)" "unprognostic (6.40e-2)" "unprognostic (2.57e-2)" "unprognostic (5.18e-1)" "unprognostic (1.17e-2)" "unprognostic (1.80e-1)" "unprognostic (2.82e-1)" "unprognostic (2.91e-1)" "unprognostic (6.78e-2)" TMEM260 "C14orf101, FLJ20392" ENSG00000070269 "Transmembrane protein 260" Q9NX78 14 56488354-56650606 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 37.3" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 848.6;Early spermatids: 203.7;Neutrophils: 213.3" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 608.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003502 Uncertain NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 2 "HPA003502: " "unprognostic (1.21e-1)" "unprognostic (1.66e-2)" "unprognostic (7.94e-2)" "unprognostic (2.98e-1)" "unprognostic (4.13e-3)" "unprognostic (2.87e-1)" "unprognostic (2.26e-2)" "unprognostic (1.23e-1)" "unprognostic (7.86e-3)" "potential prognostic favorable (3.56e-6)" "unprognostic (1.16e-2)" "unprognostic (1.54e-1)" "unprognostic (1.21e-1)" "unprognostic (4.67e-1)" "unprognostic (7.59e-2)" "unprognostic (3.20e-2)" "unprognostic (3.69e-2)" "unprognostic (9.07e-2)" "unprognostic (9.67e-2)" "unprognostic (3.24e-1)" "unprognostic (2.34e-2)" "unprognostic (1.34e-1)" "unprognostic (1.54e-3)" "unprognostic (9.02e-2)" "unprognostic (3.23e-2)" "unprognostic (2.85e-1)" "unprognostic (1.15e-1)" "unprognostic (2.32e-2)" "unprognostic (1.16e-1)" TMEM262 ENSG00000187066 "Transmembrane protein 262" E9PQX1 11 65084979-65089375 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 152 "testis: 20.5" "Group enriched" "Detected in some" 5 "Early spermatids: 184.6;Late primary spermatocytes: 125.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 11: White matter - Signal transduction" "Cluster 56: Non-specific - Sensory perception" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 12 "unprognostic (8.44e-2)" TMEM263 "C12orf23, MGC17943" ENSG00000151135 "Transmembrane protein 263" Q8WUH6 12 106955719-106978778 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Minor Salivary Gland - Minor salivary glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014453, HPA042339" Uncertain Approved Vesicles NA NA "Cluster 24: Non-specific - Transcription" "Cluster 22: Epididymis - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 38: Non-specific - Transcription" "Cluster 8: Non-specific - Secretory pathway" 15 Vesicles "HPA014453: , HPA042339: " "unprognostic (1.46e-1)" "unprognostic (3.18e-2)" "unprognostic (3.11e-3)" "unprognostic (2.71e-1)" "unprognostic (5.21e-2)" "unprognostic (1.58e-1)" "unprognostic (6.63e-2)" "unprognostic (4.34e-2)" "unprognostic (2.12e-1)" "unprognostic (6.30e-2)" "unprognostic (1.17e-1)" "unprognostic (3.84e-3)" "unprognostic (1.52e-3)" "unprognostic (4.25e-2)" "unprognostic (2.39e-3)" "unprognostic (1.46e-1)" "unprognostic (3.19e-1)" "unprognostic (2.20e-1)" "unprognostic (1.85e-2)" "unprognostic (2.86e-2)" "unprognostic (1.48e-1)" "unprognostic (8.25e-2)" "unprognostic (1.90e-1)" "unprognostic (1.31e-2)" "unprognostic (4.99e-2)" "unprognostic (3.32e-2)" "unprognostic (1.37e-1)" "potential prognostic unfavorable (7.08e-4)" "unprognostic (1.94e-1)" TMEM265 ENSG00000281991 "Transmembrane protein 265" A0A087WTH1 16 30740642-30745196 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "esophagus: 9.0;skin 1: 11.9" "Group enriched" "Detected in some" 16 "Astrocytes: 9.1;Bergmann glia: 7.5;Brain excitatory neurons: 7.3;Brain inhibitory neurons: 7.3;Choroid plexus epithelial cells: 8.5;Ependymal cells: 7.2;Microglia: 11.6;Oligodendrocyte progenitor cells: 5.8;Oligodendrocytes: 10.2;Other brain neurons: 5.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "head and neck cancer: 27.6" "Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 58: Skin - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 22: Non-specific - Basic cellular functions" "unprognostic (2.82e-1)" "unprognostic (1.10e-2)" "unprognostic (9.76e-2)" "unprognostic (8.02e-2)" "unprognostic (1.58e-2)" "unprognostic (1.70e-2)" "potential prognostic unfavorable (6.86e-7)" "unprognostic (2.77e-2)" "unprognostic (1.71e-1)" "unprognostic (1.83e-1)" "unprognostic (9.63e-3)" "unprognostic (2.28e-3)" "unprognostic (2.81e-1)" "unprognostic (8.27e-3)" "unprognostic (8.38e-2)" "potential prognostic unfavorable (7.12e-4)" "unprognostic (9.02e-2)" "unprognostic (8.40e-2)" "unprognostic (8.44e-2)" "unprognostic (1.50e-1)" "unprognostic (1.17e-1)" "unprognostic (7.41e-2)" TMEM266 "C15orf27, FLJ38190" ENSG00000169758 "Transmembrane protein 266" Q2M3C6 15 76059958-76229121 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 17.4;skeletal muscle: 5.5" "Cell type enhanced" "Detected in many" "Adipocytes: 71.6;Brain excitatory neurons: 125.2;Cardiomyocytes: 147.4;Epicardial cells: 72.8;Gonadotrophs: 104.3;Lactotrophs: 67.3;Oocytes: 101.3;Podocytes: 326.2;Retinal amacrine cells: 73.2" "Cell type enhanced" "Detected in all" "upper rhombic lip: 291.2" "Not detected" "Not detected" "Region enriched" "Detected in many" 5 "cerebellum: 18.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Podocytes, Stomach - Gastric mucous cells" "Region enriched" "Detected in all" 6 "cerebellum: 58.7" "Region enriched" "Detected in all" 5 "cerebellum: 29.6" "HPA041921, HPA049425" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 35: Non-specific - DNA binding" "Cluster 11: Neuronal - Sensory perception" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 3 "Plasma membrane, Cytosol" "HPA041921: , HPA049425: " "unprognostic (1.02e-2)" TMEM267 "C5orf28, FLJ21657" ENSG00000151881 "Transmembrane protein 267" Q0VDI3 5 43444252-43483893 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 35.7" "Cell type enhanced" "Detected in many" "Sertoli cells: 118.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059946, HPA072991" Approved Nucleoplasm,Vesicles NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 33: Thyroid gland - Tissue development" "Cluster 39: Astrocytes - Mixed function" "Cluster 29: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 9 Nucleoplasm Vesicles "HPA059946: , HPA072991: " "unprognostic (2.09e-2)" "unprognostic (7.41e-2)" "unprognostic (2.38e-3)" "unprognostic (1.07e-1)" "unprognostic (6.48e-2)" "unprognostic (3.22e-1)" "unprognostic (2.25e-2)" "unprognostic (3.71e-1)" "unprognostic (7.94e-2)" "unprognostic (3.87e-2)" "unprognostic (8.93e-2)" "unprognostic (1.80e-1)" "potential prognostic unfavorable (9.95e-4)" "unprognostic (1.01e-1)" "unprognostic (3.98e-2)" "unprognostic (3.29e-1)" "unprognostic (1.83e-1)" "unprognostic (4.08e-1)" "potential prognostic unfavorable (8.53e-4)" "unprognostic (3.60e-3)" "unprognostic (9.33e-2)" "unprognostic (7.19e-2)" "unprognostic (8.03e-3)" "unprognostic (1.42e-2)" "unprognostic (6.49e-2)" "unprognostic (1.55e-1)" "unprognostic (1.69e-1)" "potential prognostic unfavorable (1.10e-4)" "unprognostic (3.45e-2)" TMEM268 "C9orf91, DKFZp547P234, FLJ38045" ENSG00000157693 "Transmembrane protein 268" Q5VZI3 9 114611206-114646422 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Prostatic glandular cells: 69.4;Retinal pigment epithelial cells: 162.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 4.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017199 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" 1 "Plasma membrane, Cytosol" "HPA017199: " "unprognostic (1.67e-2)" "unprognostic (1.79e-1)" "unprognostic (2.56e-2)" "unprognostic (4.46e-2)" "unprognostic (1.32e-2)" "unprognostic (4.15e-1)" "unprognostic (1.54e-2)" "unprognostic (7.11e-2)" "unprognostic (8.58e-3)" "unprognostic (1.74e-1)" "unprognostic (2.34e-1)" "unprognostic (1.22e-1)" "unprognostic (2.88e-2)" "unprognostic (1.95e-2)" "unprognostic (7.73e-3)" "unprognostic (2.00e-1)" "unprognostic (2.12e-2)" "unprognostic (4.89e-1)" "unprognostic (4.25e-1)" "unprognostic (7.72e-3)" "unprognostic (4.06e-1)" "unprognostic (2.25e-1)" "unprognostic (9.73e-2)" "unprognostic (2.23e-1)" "unprognostic (2.75e-2)" "unprognostic (4.92e-2)" "unprognostic (9.16e-3)" "potential prognostic unfavorable (4.87e-4)" "unprognostic (3.89e-2)" TMEM269 ENSG00000274386 "Transmembrane protein 269" A0A1B0GVZ9 1 42784991-42816619 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in many" 4 "Late spermatids: 122.1" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" NA NA "Cluster 48: Non-specific - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" TMEM270 "MGC26719, WBSCR28" ENSG00000175877 "Transmembrane protein 270" Q6UE05 7 73861159-73865890 "Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 220 "testis: 74.6" "Group enriched" "Detected in some" 96 "Early spermatids: 1090.5;Late primary spermatocytes: 310.6;Late spermatids: 387.4" "Cell type enriched" "Detected in single" 5 "ependymal cell: 3.6" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA077196 Approved Vesicles NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 27: Breast cancer - Unknown function" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 1 Vesicles "HPA077196: " "unprognostic (1.80e-2)" "unprognostic (3.58e-1)" "potential prognostic unfavorable (8.36e-4)" TMEM271 ENSG00000273238 "Transmembrane protein 271" A0A286YF58 4 573880-576295 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 19.6;pituitary gland: 6.0;skin 1: 3.5" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 10.6;Basal keratinocytes: 4.0;Brain excitatory neurons: 11.2;Brain inhibitory neurons: 12.4;Corticotrophs: 3.1;Gonadotrophs: 3.6;Oligodendrocyte progenitor cells: 5.8;Other brain neurons: 15.8;Retinal amacrine cells: 10.6;Somatotrophs: 7.1;Thyrotrophs: 3.1" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in single" 4 "Glioblastoma Multiforme (TCGA): 1.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 2.1;Neuroblastoma: 1.4" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 98: Neurons - Neurotransmission & signaling" "unprognostic (1.67e-2)" "unprognostic (4.39e-2)" TMEM272 "FLJ37307, LINC00282, NCRNA00282" ENSG00000281106 "Transmembrane protein 272" A0A1B0GTI8 13 51813347-51845177 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "brain: 13.8" "Group enriched" "Detected in some" 4 "Early spermatids: 3.0;Late spermatids: 10.6;Melanocytes: 6.3" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in many" "basal ganglia: 34.9" "Immune cell enriched" "Detected in single" 89 "neutrophil: 40.4" "Lineage enriched" "Detected in single" 89 "granulocytes: 40.4" "Cancer enhanced" "Detected in single" "skin cancer: 1.6" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" TMEM273 "C10orf128, Em:AC084727.5" ENSG00000204161 "Transmembrane protein 273" Q5T292 10 49154725-49188585 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "B-cells: 29.8;cDC: 51.2;Hofbauer cells: 193.7;Kupffer cells: 32.8;Lymphatic endothelial cells: 24.7;Macrophages: 47.3;Mast cells: 91.5;Microglia: 58.4;Neutrophils: 86.9;Oligodendrocytes: 27.0;Pericytes: 24.3;Vascular endothelial cells: 62.2" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 78.6;leukocyte: 31.0;oligodendrocyte: 42.1;pericyte: 26.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "eosinophil: 269.8" "Lineage enriched" "Detected in many" 7 "granulocytes: 269.8" "Group enriched" "Detected in some" 7 "Kidney cancer: 10.9;Leukemia: 19.7;lymphoma: 14.3;Myeloma: 6.5" "Breast - Endothelial cells, Colon - Endothelial cells, Minor Salivary Gland - Endothelial cells, Skeletal muscle - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA058166 Approved NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 30: White matter - Myelination" "Cluster 50: Lymphoma - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "HPA058166: " "unprognostic (3.32e-1)" "unprognostic (7.95e-2)" "unprognostic (6.34e-2)" "unprognostic (1.89e-1)" "unprognostic (1.69e-1)" "unprognostic (2.20e-1)" "unprognostic (5.13e-2)" "unprognostic (3.94e-2)" "unprognostic (7.36e-2)" "unprognostic (3.61e-2)" "unprognostic (3.54e-2)" "unprognostic (9.51e-2)" "unprognostic (4.07e-2)" "potential prognostic favorable (1.07e-4)" "unprognostic (3.81e-1)" "unprognostic (4.14e-2)" "unprognostic (2.09e-1)" "unprognostic (8.63e-2)" "unprognostic (3.01e-1)" "unprognostic (1.62e-1)" "unprognostic (9.25e-2)" "unprognostic (4.39e-1)" "unprognostic (1.68e-1)" "unprognostic (1.28e-1)" "unprognostic (1.55e-1)" "unprognostic (4.00e-2)" "unprognostic (1.39e-2)" "potential prognostic unfavorable (6.80e-4)" "unprognostic (1.60e-1)" TMEM275 ENSG00000282881 "Transmembrane protein 275" A0A0U1RQS6 1 46532166-46543969 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.3" "Group enriched" "Detected in some" 14 "Early spermatids: 125.4;Late spermatids: 174.8" "Cell type enhanced" "Detected in many" "deep-layer corticothalamic and 6b: 29.5;deep-layer near-projecting: 21.2;mammillary body: 20.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Group enriched" "Detected in some" 5 "amygdala: 1.2;basal ganglia: 1.6;hypothalamus: 1.2" "Low region specificity" "Detected in some" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 34: Testis cancer - Unknown function" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" TMEM276 ENSG00000291317 "Transmembrane protein 276" Q6ZMK1 8 144463817-144465667 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cholangiocytes: 3.9;Megakaryocytes: 6.2;Retinal ganglion cells: 3.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 70: Non-specific - Protein processing" "Cluster 39: Astrocytes - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 15: Non-specific - Protein processing" 2 TMEM30A "C6orf67, CDC50A, FLJ10856" ENSG00000112697 "Transmembrane protein 30A" Q9NV96 6 75252924-75284948 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Corticotrophs: 252.6;Esophageal apical cells: 234.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014561 Approved NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 73: Brain - Neuronal signaling" "Cluster 21: Non-specific - Metabolism" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 17: Non-specific - RNA processing" 25 "HPA014561: " "unprognostic (1.30e-2)" "unprognostic (5.85e-2)" "unprognostic (4.06e-1)" "unprognostic (3.50e-2)" "unprognostic (2.36e-2)" "unprognostic (9.25e-2)" "unprognostic (1.70e-1)" "unprognostic (3.01e-1)" "unprognostic (1.25e-1)" "unprognostic (9.88e-2)" "validated prognostic favorable (1.21e-6)" "validated prognostic favorable (8.06e-4)" "unprognostic (2.46e-1)" "unprognostic (7.46e-2)" "unprognostic (8.97e-3)" "unprognostic (3.15e-1)" "unprognostic (1.76e-1)" "unprognostic (1.60e-1)" "unprognostic (3.07e-1)" "unprognostic (4.11e-1)" "potential prognostic unfavorable (1.28e-4)" "unprognostic (2.00e-1)" "unprognostic (3.58e-2)" "unprognostic (8.04e-2)" "unprognostic (4.64e-1)" "unprognostic (2.34e-2)" "unprognostic (1.61e-1)" "unprognostic (3.70e-2)" "unprognostic (2.07e-1)" "unprognostic (1.00e-1)" "unprognostic (9.75e-2)" TMEM30B CDC50B ENSG00000182107 "Transmembrane protein 30B" Q3MIR4 14 61277370-61281761 "Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 124.2;Foveolar cells: 97.2;Parietal cells: 132.6;Urothelial cells: 112.2" "Group enriched" "Detected in some" 9 "fibroblast: 9.4;pericyte: 16.6;vascular associated smooth muscle cell: 20.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA043162 Uncertain NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 17: Intestine - Digestion" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 69: Urothelial cells - Basic cellular functions" 8 "HPA043162: " "unprognostic (1.82e-1)" "unprognostic (1.08e-1)" "unprognostic (1.54e-1)" "unprognostic (7.86e-2)" "unprognostic (2.58e-1)" "unprognostic (2.23e-1)" "unprognostic (5.02e-2)" "unprognostic (3.40e-1)" "unprognostic (2.09e-1)" "unprognostic (1.62e-2)" "unprognostic (1.19e-1)" "unprognostic (1.24e-2)" "unprognostic (6.99e-3)" "unprognostic (4.59e-3)" "unprognostic (4.55e-2)" "unprognostic (1.20e-1)" "unprognostic (2.38e-1)" "unprognostic (2.67e-1)" "unprognostic (1.01e-2)" "unprognostic (2.87e-2)" "unprognostic (2.08e-1)" "unprognostic (9.42e-2)" "unprognostic (2.77e-2)" "potential prognostic unfavorable (6.64e-4)" "unprognostic (4.55e-1)" "unprognostic (3.60e-1)" "unprognostic (2.19e-1)" "unprognostic (2.05e-1)" TMEM31 MGC39655 ENSG00000179363 "Transmembrane protein 31" Q5JXX7 X 103710909-103714032 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 48 "testis: 105.6" "Cell type enriched" "Detected in some" 8 "Late spermatids: 6304.2" "Low cell type specificity" "Detected in single" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 2.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Low region specificity" "Detected in all" HPA052760 Approved "Nucleoli fibrillar center" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 32 "Nucleoli fibrillar center" "HPA052760: " "unprognostic (3.73e-1)" "unprognostic (2.49e-1)" "unprognostic (6.42e-3)" "unprognostic (3.66e-1)" "unprognostic (1.51e-2)" TMEM33 "FLJ10525, Pom33" ENSG00000109133 "Transmembrane protein 33" P57088 4 41935129-41960803 "Predicted membrane proteins, Transporters" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 246.2;Syncytiotrophoblasts: 207.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075863 Approved NA NA 17000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 76: Non-specific - Metabolism" "Cluster 30: White matter - Myelination" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 24 "HPA075863: " "unprognostic (4.32e-1)" "unprognostic (2.02e-3)" "unprognostic (4.59e-2)" "potential prognostic unfavorable (2.53e-4)" "unprognostic (1.60e-2)" "unprognostic (2.29e-1)" "unprognostic (4.61e-2)" "unprognostic (4.28e-3)" "unprognostic (9.19e-2)" "unprognostic (2.92e-2)" "potential prognostic favorable (1.09e-4)" "unprognostic (1.21e-2)" "unprognostic (1.60e-1)" "unprognostic (3.47e-2)" "unprognostic (2.59e-1)" "unprognostic (5.55e-3)" "unprognostic (7.88e-2)" "unprognostic (7.58e-2)" "unprognostic (2.85e-1)" "unprognostic (2.65e-1)" "unprognostic (5.73e-2)" "unprognostic (5.17e-3)" "unprognostic (2.03e-1)" "unprognostic (2.77e-1)" "unprognostic (9.43e-2)" "unprognostic (3.76e-2)" "potential prognostic unfavorable (9.53e-4)" "unprognostic (2.33e-2)" "unprognostic (1.53e-1)" "unprognostic (1.54e-2)" "unprognostic (9.75e-3)" TMEM35A "FLJ14084, NACHO, TMEM35, TUF-1" ENSG00000126950 "Transmembrane protein 35A" Q53FP2 X 101078879-101096367 "Predicted membrane proteins, Transporters" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 55.8;intestine: 37.3;seminal vesicle: 48.0" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 33.5;Brain inhibitory neurons: 41.5;Decidual stromal cells: 36.7;Oligodendrocyte progenitor cells: 24.6;Other brain neurons: 63.3;Peritubular myoid cells: 19.4;Retinal bipolar cells: 24.3;Retinal horizontal cells: 14.0;Smooth muscle cells: 34.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 14.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 13.6" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Pituitary gland - Thyrotropes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048583 Enhanced Supported Supported "Vesicles,Focal adhesion sites,Cytosol" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 98: Neurons - Neurotransmission & signaling" 22 Vesicles "Focal adhesion sites, Cytosol" "HPA048583: " "unprognostic (9.97e-2)" "unprognostic (1.21e-1)" "unprognostic (8.74e-2)" "unprognostic (1.14e-1)" "unprognostic (1.55e-2)" "potential prognostic favorable (1.60e-5)" "potential prognostic unfavorable (3.89e-5)" "potential prognostic favorable (3.60e-4)" "unprognostic (1.77e-1)" "unprognostic (1.50e-1)" "unprognostic (1.18e-1)" "unprognostic (4.58e-2)" "unprognostic (2.39e-1)" "unprognostic (1.83e-1)" "unprognostic (2.09e-2)" "unprognostic (5.06e-2)" "unprognostic (1.67e-2)" "unprognostic (2.66e-2)" "unprognostic (1.70e-1)" "unprognostic (1.21e-1)" TMEM35B ZMYM6NB ENSG00000243749 "Transmembrane protein 35B" Q8NCS4 1 34981380-34985347 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in single" "Microglia: 1.1" "Cell type enhanced" "Detected in some" "Bergmann glia: 1.2;endothelial cell: 1.3;pericyte: 1.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051024 Uncertain Approved Nucleoplasm,Nucleoli NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 8: Immune cells - Immune response" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 18: Adrenal cortex cells - Steroidogensis" 5 "Nucleoplasm, Nucleoli" "HPA051024: " "unprognostic (2.80e-1)" "unprognostic (3.71e-2)" "unprognostic (2.37e-2)" "unprognostic (3.38e-1)" "unprognostic (1.13e-1)" "unprognostic (2.11e-3)" "unprognostic (4.05e-2)" "unprognostic (7.47e-2)" "unprognostic (2.31e-1)" "potential prognostic favorable (4.39e-4)" "unprognostic (4.38e-2)" "unprognostic (1.03e-1)" "unprognostic (2.12e-2)" "unprognostic (1.48e-1)" "unprognostic (1.50e-1)" "unprognostic (4.71e-2)" "unprognostic (4.99e-3)" "unprognostic (1.32e-3)" "unprognostic (3.75e-1)" "unprognostic (2.14e-2)" "unprognostic (3.89e-1)" "unprognostic (4.38e-2)" "unprognostic (2.42e-1)" "unprognostic (1.25e-1)" "unprognostic (5.13e-2)" "unprognostic (4.28e-1)" "unprognostic (1.39e-1)" "unprognostic (7.65e-2)" "unprognostic (2.27e-1)" TMEM37 "PR, PR1" ENSG00000171227 "Transmembrane protein 37" Q8WXS4 2 119429901-119438504 "Predicted intracellular proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 94.3;liver: 94.5;parathyroid gland: 117.1" "Cell type enhanced" "Detected in many" "Colonocytes: 127.1;Decidual stromal cells: 457.9;Enterocytes: 545.0;Esophageal apical cells: 121.4;Hepatocytes: 218.8;Hofbauer cells: 92.1;Kupffer cells: 164.0;Müller glia: 124.7;Syncytiotrophoblasts: 154.1" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 2.6;endothelial cell: 7.6;fibroblast: 4.2" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 165.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 32.2" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Skeletal muscle - Fibroblasts, Spleen - Macrophages, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "HPA053794, HPA076947" Enhanced Approved "Golgi apparatus" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 76: Non-specific - Metabolism" "Cluster 38: Sub-cortical - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" "Golgi apparatus" "HPA053794: , HPA076947: " "unprognostic (6.57e-2)" "unprognostic (4.06e-2)" "unprognostic (2.56e-3)" "unprognostic (4.62e-2)" "unprognostic (2.29e-1)" "unprognostic (1.88e-1)" "unprognostic (6.49e-2)" "unprognostic (7.57e-2)" "unprognostic (1.60e-1)" "unprognostic (8.30e-2)" "validated prognostic favorable (7.25e-10)" "validated prognostic favorable (2.23e-4)" "unprognostic (1.12e-1)" "unprognostic (8.79e-2)" "unprognostic (3.33e-3)" "unprognostic (1.04e-1)" "unprognostic (4.70e-2)" "unprognostic (9.29e-2)" "unprognostic (4.06e-1)" "unprognostic (1.11e-1)" "unprognostic (1.54e-1)" "unprognostic (1.08e-1)" "unprognostic (8.72e-2)" "unprognostic (6.79e-2)" "unprognostic (1.01e-1)" "unprognostic (1.96e-1)" "unprognostic (1.49e-1)" "unprognostic (7.46e-3)" "unprognostic (4.62e-2)" "unprognostic (1.66e-1)" "unprognostic (1.56e-1)" TMEM38A "MGC3169, TRIC-A" ENSG00000072954 "Transmembrane protein 38A" Q9H6F2 19 16661139-16690023 "Predicted membrane proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 543.6;tongue: 242.4" "Cell type enriched" "Detected in many" 4 "Myonuclei: 848.0" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 7 "Kidney Chromophobe (TCGA): 102.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 36.7;eosinophil: 12.3" "Lineage enriched" "Detected in many" 6 "granulocytes: 36.7" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048100, HPA050463" Enhanced Approved Nucleoplasm NA NA "Cluster 32: Basophils - Transcription" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 23: Choroid plexus - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" Nucleoplasm "HPA048100: , HPA050463: " "unprognostic (2.69e-1)" "unprognostic (1.36e-1)" "unprognostic (2.09e-2)" "unprognostic (1.20e-1)" "unprognostic (1.85e-1)" "unprognostic (2.22e-1)" "unprognostic (1.26e-1)" "unprognostic (2.80e-2)" "unprognostic (1.66e-1)" "unprognostic (1.80e-2)" "validated prognostic favorable (1.51e-7)" "validated prognostic favorable (2.14e-4)" "unprognostic (4.09e-2)" "unprognostic (1.12e-1)" "unprognostic (1.20e-2)" "unprognostic (1.68e-2)" "unprognostic (9.96e-2)" "unprognostic (2.50e-3)" "unprognostic (5.91e-2)" "unprognostic (1.70e-3)" "unprognostic (1.30e-2)" "unprognostic (2.52e-1)" "unprognostic (4.10e-3)" "unprognostic (2.26e-1)" "unprognostic (1.20e-1)" "unprognostic (1.44e-1)" "unprognostic (2.15e-2)" "unprognostic (1.08e-1)" "unprognostic (1.58e-1)" "unprognostic (2.63e-3)" "unprognostic (7.26e-2)" TMEM38B "bA219P18.1, C9orf87, D4Ertd89e, FLJ10493, TRIC-B" ENSG00000095209 "Transmembrane protein 38B" Q9NVV0 9 105694541-105776629 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 70.8;tongue: 58.0" "Cell type enhanced" "Detected in many" "Early spermatids: 322.3;Late primary spermatocytes: 239.6;Late spermatids: 834.8;Myonuclei: 769.9;Thymic myoid cells: 213.5" "Cell type enhanced" "Detected in all" "vascular associated smooth muscle cell: 135.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018465 Uncertain NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 55: Myocytes - Oxidative muscle function" 5 "HPA018465: " "unprognostic (3.33e-1)" "unprognostic (2.27e-1)" "unprognostic (3.22e-1)" "unprognostic (8.58e-2)" "unprognostic (2.86e-1)" "unprognostic (6.53e-2)" "unprognostic (1.19e-1)" "unprognostic (1.36e-2)" "unprognostic (1.09e-1)" "unprognostic (1.99e-2)" "validated prognostic favorable (7.61e-12)" "validated prognostic favorable (2.82e-4)" "unprognostic (2.38e-1)" "unprognostic (2.00e-2)" "potential prognostic unfavorable (9.27e-5)" "unprognostic (1.12e-2)" "unprognostic (4.10e-2)" "unprognostic (1.32e-1)" "unprognostic (6.91e-2)" "unprognostic (2.76e-1)" "unprognostic (1.49e-1)" "unprognostic (4.12e-2)" "unprognostic (1.86e-1)" "unprognostic (2.84e-2)" "unprognostic (2.70e-2)" "unprognostic (1.31e-2)" "unprognostic (1.36e-1)" "unprognostic (3.67e-2)" "unprognostic (1.80e-1)" "unprognostic (5.25e-2)" "unprognostic (2.77e-2)" TMEM39A "FLJ10902, SUSR2" ENSG00000176142 "Transmembrane protein 39A" Q9NV64 3 119428949-119468830 "Predicted membrane proteins, Transporters" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Monocyte progenitors: 140.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039140 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 63: Non-specific - Protein processing" "Cluster 8: Non-specific - Secretory pathway" 3 Nucleoplasm Vesicles "HPA039140: " "unprognostic (3.26e-1)" "unprognostic (1.49e-1)" "unprognostic (3.04e-1)" "unprognostic (1.94e-2)" "unprognostic (3.06e-1)" "unprognostic (7.20e-2)" "unprognostic (5.08e-2)" "unprognostic (3.03e-2)" "unprognostic (2.82e-1)" "unprognostic (2.00e-2)" "potential prognostic favorable (9.09e-5)" "unprognostic (3.73e-1)" "unprognostic (6.89e-2)" "unprognostic (9.11e-2)" "unprognostic (6.18e-3)" "unprognostic (2.95e-1)" "unprognostic (8.52e-3)" "unprognostic (1.83e-1)" "unprognostic (1.27e-1)" "unprognostic (5.87e-2)" "unprognostic (1.39e-3)" "unprognostic (3.48e-3)" "unprognostic (4.47e-3)" "unprognostic (1.02e-1)" "unprognostic (5.71e-2)" "unprognostic (3.02e-2)" "unprognostic (4.56e-1)" "unprognostic (1.82e-1)" "unprognostic (4.56e-1)" "unprognostic (7.91e-3)" "unprognostic (1.65e-1)" TMEM39B FLJ10315 ENSG00000121775 "Transmembrane protein 39B" Q9GZU3 1 32072031-32102866 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Platelets: 62.2;Syncytiotrophoblasts: 55.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040191, HPA040224" Approved Approved Vesicles NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 75: Ovary - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 47: Platelets - Hemostasis" Vesicles "HPA040191: , HPA040224: " "unprognostic (1.61e-2)" "unprognostic (3.15e-1)" "unprognostic (3.89e-1)" "unprognostic (1.55e-2)" "unprognostic (1.19e-1)" "unprognostic (4.24e-2)" "unprognostic (1.80e-1)" "unprognostic (5.68e-2)" "unprognostic (2.46e-1)" "unprognostic (7.79e-2)" "unprognostic (2.26e-2)" "unprognostic (1.97e-2)" "unprognostic (2.17e-1)" "unprognostic (2.99e-3)" "unprognostic (9.11e-3)" "unprognostic (1.76e-1)" "unprognostic (1.33e-1)" "unprognostic (1.23e-2)" "unprognostic (2.74e-2)" "unprognostic (5.00e-2)" "unprognostic (7.01e-3)" "unprognostic (1.66e-2)" "unprognostic (1.70e-1)" "unprognostic (1.20e-1)" "unprognostic (3.20e-1)" "unprognostic (2.12e-1)" "unprognostic (2.46e-1)" "unprognostic (1.57e-2)" "unprognostic (3.31e-1)" "unprognostic (8.15e-2)" "unprognostic (4.12e-2)" TMEM40 FLJ11036 ENSG00000088726 "Transmembrane protein 40" Q8WWA1 3 12733528-12769457 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "cervix: 55.3;esophagus: 213.6;skin 1: 61.8;vagina: 77.3" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 5067.0;Esophageal suprabasal cells: 1124.4;Megakaryocytes: 364.7;Platelets: 2578.0;Suprabasal keratinocytes: 487.9;Syncytiotrophoblasts: 1099.7" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 53.7;Head and Neck Squamous Cell Carcinoma (TCGA): 70.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 6.0" "Lineage enriched" "Detected in single" 7 "granulocytes: 6.0" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 63.9;head and neck cancer: 46.8" "Heart muscle - Cardiomyocytes, Prostate - Urothelial cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA044165, HPA073122" Enhanced Approved "Plasma membrane,Cytosol" NA NA 1100000 "Cluster 21: Neutrophils - Unknown function" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 9: Non-specific - Receptor signaling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 84: Apical squamous epithelium - Cornification" 3 "Plasma membrane" Cytosol "HPA044165: , HPA073122: " "unprognostic (2.37e-1)" "unprognostic (8.59e-3)" "unprognostic (3.80e-1)" "unprognostic (1.67e-2)" "unprognostic (1.04e-1)" "unprognostic (1.99e-1)" "potential prognostic unfavorable (3.61e-4)" "unprognostic (1.24e-1)" "unprognostic (3.64e-1)" "unprognostic (1.65e-2)" "unprognostic (5.69e-2)" "unprognostic (1.31e-3)" "potential prognostic unfavorable (6.31e-5)" "unprognostic (3.38e-1)" "unprognostic (3.31e-2)" "unprognostic (1.84e-1)" "unprognostic (2.45e-1)" "unprognostic (1.77e-1)" "unprognostic (3.93e-2)" TMEM41A MGC15397 ENSG00000163900 "Transmembrane protein 41A" Q96HV5 3 185476496-185499057 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 244.2;Esophageal apical cells: 152.2;Esophageal suprabasal cells: 179.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "HPA059101, HPA059790" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 77: Intestine - Digestion" "Cluster 38: Sub-cortical - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 1: Enterocytes - Absorption and Digestion" 7 Nucleoplasm "Golgi apparatus, Cytosol" "HPA059101: , HPA059790: " "unprognostic (8.90e-3)" "potential prognostic unfavorable (1.16e-4)" "unprognostic (5.14e-2)" "unprognostic (2.80e-1)" "unprognostic (1.62e-2)" "unprognostic (1.61e-1)" "unprognostic (1.61e-1)" "unprognostic (1.23e-1)" "unprognostic (2.18e-1)" "unprognostic (3.40e-2)" "unprognostic (2.36e-2)" "unprognostic (2.16e-1)" "unprognostic (8.10e-2)" "validated prognostic unfavorable (6.44e-4)" "validated prognostic unfavorable (4.74e-4)" "potential prognostic unfavorable (9.38e-4)" "unprognostic (9.59e-3)" "unprognostic (1.40e-2)" "unprognostic (6.09e-3)" "unprognostic (3.73e-1)" "unprognostic (8.45e-2)" "validated prognostic unfavorable (1.01e-4)" "validated prognostic unfavorable (4.53e-4)" "unprognostic (9.93e-3)" "unprognostic (8.66e-2)" "unprognostic (4.36e-1)" "unprognostic (3.77e-1)" "unprognostic (1.93e-1)" "unprognostic (3.76e-1)" "unprognostic (5.72e-2)" "unprognostic (4.39e-2)" TMEM41B KIAA0033 ENSG00000166471 "Transmembrane protein 41B" Q5BJD5 11 9280654-9314636 "Essential proteins, Predicted membrane proteins, Transporters" "Autophagy, Host-virus interaction, Lipid transport, Neurogenesis, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014946 Uncertain Approved Peroxisomes NA NA "Cluster 24: Non-specific - Transcription" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 6 Peroxisomes "HPA014946: " "unprognostic (8.27e-2)" "unprognostic (3.56e-1)" "unprognostic (7.47e-2)" "unprognostic (5.14e-2)" "unprognostic (1.33e-1)" "unprognostic (2.41e-2)" "unprognostic (9.31e-3)" "unprognostic (2.07e-2)" "unprognostic (2.54e-1)" "potential prognostic unfavorable (8.10e-4)" "unprognostic (1.80e-1)" "unprognostic (1.53e-2)" "unprognostic (2.13e-1)" "potential prognostic unfavorable (3.18e-5)" "unprognostic (2.71e-1)" "unprognostic (4.05e-1)" "unprognostic (1.22e-1)" "unprognostic (2.87e-1)" "unprognostic (1.03e-1)" "unprognostic (8.56e-2)" "unprognostic (3.01e-2)" "unprognostic (5.59e-3)" "unprognostic (2.51e-3)" "unprognostic (4.36e-1)" "unprognostic (2.65e-2)" "unprognostic (1.26e-3)" "unprognostic (1.26e-1)" "unprognostic (2.83e-1)" "unprognostic (1.69e-1)" "unprognostic (2.67e-1)" "unprognostic (1.78e-2)" TMEM42 MGC29956 ENSG00000169964 "Transmembrane protein 42" Q69YG0 3 44861904-44865670 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Myosatellite cells: 1.2;Thymocytes: 1.7" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052569 Uncertain Uncertain Nucleoplasm,Nucleoli NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 80: Oligodendrocytes - Myelination" 41 Nucleoplasm Nucleoli "HPA052569: " "unprognostic (6.86e-2)" "unprognostic (8.63e-3)" "unprognostic (7.34e-2)" "unprognostic (9.38e-2)" "unprognostic (1.04e-2)" "unprognostic (4.54e-2)" "unprognostic (3.11e-2)" "unprognostic (3.83e-1)" "unprognostic (7.71e-2)" "unprognostic (1.25e-1)" "unprognostic (1.81e-1)" "unprognostic (2.99e-1)" "potential prognostic favorable (1.84e-4)" "unprognostic (1.18e-3)" "potential prognostic unfavorable (2.52e-4)" "unprognostic (2.71e-1)" "unprognostic (1.09e-1)" "unprognostic (1.30e-1)" "unprognostic (9.06e-2)" "unprognostic (6.91e-2)" "unprognostic (2.31e-1)" "unprognostic (3.82e-2)" "unprognostic (3.74e-2)" "unprognostic (1.80e-1)" "unprognostic (4.92e-2)" "unprognostic (2.30e-2)" "unprognostic (2.19e-1)" "potential prognostic unfavorable (8.21e-4)" "unprognostic (9.62e-2)" "unprognostic (7.39e-2)" "unprognostic (2.37e-1)" TMEM43 "ARVD5, DKFZp586G1919, LUMA, MGC3222" ENSG00000170876 "Transmembrane protein 43" Q9BTV4 3 14125015-14143680 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Immunity, Innate immunity" "Cardiomyopathy, Deafness, Disease variant, Emery-Dreifuss muscular dystrophy, Neuropathy, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 55.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Pituitary gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019198 Approved NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 9: T-cells - Adaptive immunity: Regulation" 59 "HPA019198: " "unprognostic (1.11e-1)" "unprognostic (3.20e-3)" "unprognostic (1.01e-1)" "unprognostic (1.12e-2)" "unprognostic (5.72e-2)" "potential prognostic unfavorable (3.21e-5)" "unprognostic (1.32e-1)" "unprognostic (6.77e-2)" "unprognostic (9.80e-2)" "unprognostic (1.31e-2)" "unprognostic (1.79e-3)" "unprognostic (1.57e-1)" "unprognostic (6.03e-2)" "potential prognostic unfavorable (8.44e-4)" "unprognostic (1.57e-2)" "unprognostic (3.20e-1)" "unprognostic (4.01e-2)" "unprognostic (1.75e-1)" "unprognostic (2.18e-1)" "unprognostic (1.70e-2)" "unprognostic (5.78e-2)" "unprognostic (2.02e-3)" "unprognostic (1.87e-1)" "unprognostic (7.96e-2)" "unprognostic (6.29e-3)" "unprognostic (2.65e-3)" "unprognostic (3.46e-1)" "unprognostic (2.43e-2)" "unprognostic (3.24e-1)" "unprognostic (2.77e-1)" "unprognostic (1.34e-2)" TMEM44 DKFZp686O18124 ENSG00000145014 "Transmembrane protein 44" Q2T9K0 3 194587673-194633689 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Colonocytes: 43.3;Epididymal principal cells: 45.7;Goblet cells: 44.2;Hematopoietic stem cells: 43.7;Lymphatic endothelial cells: 52.2;Mast cells: 119.0;Vascular endothelial cells: 58.5" "Cell type enhanced" "Detected in all" "endothelial cell: 97.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "basophil: 3.6;NK-cell: 8.3" "Group enriched" "Detected in many" 9 "granulocytes: 3.6;NK-cells: 8.3" "Low cancer specificity" "Detected in all" "Adrenal gland - Endothelial cells, Liver - Vascular endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA043718 Uncertain Approved Cytosol NA NA "Cluster 41: Basophils - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" Cytosol "HPA043718: " "unprognostic (2.23e-1)" "unprognostic (1.39e-1)" "unprognostic (9.30e-2)" "unprognostic (5.69e-2)" "unprognostic (3.22e-1)" "unprognostic (3.39e-2)" "unprognostic (5.10e-3)" "unprognostic (1.46e-1)" "unprognostic (5.59e-2)" "unprognostic (9.36e-3)" "validated prognostic unfavorable (7.57e-6)" "validated prognostic unfavorable (8.61e-4)" "unprognostic (2.07e-1)" "unprognostic (6.99e-3)" "unprognostic (1.61e-2)" "potential prognostic unfavorable (5.96e-4)" "unprognostic (4.27e-3)" "unprognostic (1.20e-1)" "unprognostic (1.95e-1)" "unprognostic (2.84e-2)" "unprognostic (6.46e-2)" "validated prognostic unfavorable (3.05e-4)" "validated prognostic unfavorable (2.56e-4)" "unprognostic (7.03e-2)" "unprognostic (4.30e-2)" "unprognostic (8.12e-3)" "unprognostic (5.73e-3)" "unprognostic (7.47e-2)" "unprognostic (2.26e-1)" "unprognostic (1.25e-1)" "unprognostic (1.09e-2)" TMEM45A "DERP7, FLJ10134" ENSG00000181458 "Transmembrane protein 45A" Q9NWC5 3 100492619-100577444 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "skin 1: 449.0" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 174.8;Decidual stromal cells: 704.2;Early spermatids: 223.0;Hepatocytes: 146.3;Lactotrophs: 112.7;Late primary spermatocytes: 137.9;Somatotrophs: 134.9;Suprabasal keratinocytes: 282.6" "Cell type enhanced" "Detected in many" "fibroblast: 59.3;oligodendrocyte precursor cell: 35.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Macrophages, Prostate - Fibroblasts, Skin - Keratinocyte (other), Spleen - Fibroblasts_1, Stomach - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA062101 Uncertain Approved "Endoplasmic reticulum,Vesicles" NA NA "Cluster 37: Skin - Keratinization" "Cluster 33: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 108: Fibroblasts - ECM organization" 7 "Endoplasmic reticulum" Vesicles "HPA062101: " "unprognostic (4.49e-1)" "unprognostic (3.98e-3)" "unprognostic (3.73e-1)" "unprognostic (5.94e-2)" "unprognostic (2.37e-1)" "unprognostic (1.04e-1)" "unprognostic (2.76e-2)" "unprognostic (4.20e-2)" "unprognostic (1.33e-1)" "unprognostic (2.22e-1)" "potential prognostic unfavorable (5.43e-4)" "unprognostic (1.19e-3)" "unprognostic (1.30e-3)" "unprognostic (7.25e-3)" "unprognostic (1.41e-1)" "unprognostic (2.99e-3)" "unprognostic (9.42e-2)" "unprognostic (6.75e-2)" "potential prognostic unfavorable (4.69e-4)" "unprognostic (1.85e-2)" "unprognostic (1.48e-1)" "unprognostic (5.38e-2)" "unprognostic (3.08e-2)" "unprognostic (1.01e-1)" "unprognostic (5.51e-2)" "unprognostic (1.82e-1)" "unprognostic (9.43e-2)" "potential prognostic unfavorable (3.27e-4)" "unprognostic (6.14e-2)" "potential prognostic unfavorable (1.54e-4)" "unprognostic (3.49e-1)" TMEM45B "BC016153, FLJ40787" ENSG00000151715 "Transmembrane protein 45B" Q96B21 11 129815848-129860003 "Predicted membrane proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 64.1;intestine: 128.3" "Cell type enhanced" "Detected in many" "Colonocytes: 406.1;Enteric transient amplifying cells: 185.3;Enterocytes: 465.8;Esophageal apical cells: 1167.6;Esophageal suprabasal cells: 263.8;Prostatic club cells: 185.9;Respiratory ciliated cells: 167.5;Tuft cells: 230.6;Urothelial cells: 304.0" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 22.0;endothelial cell: 57.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory CD4 T-cell: 3.1;naive CD4 T-cell: 3.6;neutrophil: 11.8" "Group enriched" "Detected in many" 14 "granulocytes: 11.8;T-cells: 3.6" "Cancer enhanced" "Detected in many" "colorectal cancer: 56.4;prostate cancer: 85.3" "Adrenal gland - Adrenal medulla cells, Breast - Breast glandular cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Prostate - Urothelial cells, Spleen - Neutrophils_2, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA015474, HPA015878" Approved Approved Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 31 Nucleoplasm "HPA015474: , HPA015878: " "unprognostic (1.15e-1)" "unprognostic (1.59e-2)" "unprognostic (4.78e-2)" "unprognostic (3.77e-1)" "unprognostic (1.81e-2)" "unprognostic (2.79e-1)" "unprognostic (6.92e-3)" "unprognostic (9.09e-2)" "unprognostic (4.73e-2)" "unprognostic (1.86e-2)" "unprognostic (1.40e-2)" "unprognostic (6.51e-3)" "potential prognostic unfavorable (8.02e-4)" "unprognostic (3.92e-2)" "unprognostic (1.15e-1)" "unprognostic (3.82e-2)" "unprognostic (8.57e-3)" "unprognostic (2.40e-2)" "unprognostic (1.13e-1)" "unprognostic (2.74e-3)" "unprognostic (1.30e-1)" "unprognostic (1.47e-1)" "unprognostic (3.07e-1)" "unprognostic (1.36e-1)" "unprognostic (8.34e-3)" "unprognostic (1.11e-1)" "unprognostic (4.25e-2)" "unprognostic (4.05e-2)" "unprognostic (3.38e-1)" "unprognostic (1.16e-1)" "unprognostic (1.57e-1)" TMEM47 "BCMP1, DKFZp564E153, DKFZP761J17121, TM4SF10, VAB-9" ENSG00000147027 "Transmembrane protein 47" Q9BQJ4 X 34627075-34657285 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 105.1" "Cell type enhanced" "Detected in many" "Astrocytes: 92.3;Ependymal cells: 225.7;Fallopian tube ciliated cells: 76.7;Melanocytes: 76.0;Müller glia: 141.6;Peritubular myoid cells: 91.5;Pituicytes/FSCs: 177.2;Retinal pigment epithelial cells: 81.0;Smooth muscle cells: 130.6;Vascular smooth muscle cells: 123.4" "Cell type enhanced" "Detected in all" "ependymal cell: 335.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Endothelial cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Spleen - Fibroblasts_1, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046658 Approved Approved "Nuclear membrane" NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 5 "Nuclear membrane" "HPA046658: " "unprognostic (4.08e-3)" "unprognostic (1.79e-1)" "unprognostic (1.11e-2)" "unprognostic (1.23e-2)" "unprognostic (9.71e-3)" "unprognostic (5.28e-2)" "unprognostic (2.32e-1)" "unprognostic (2.63e-3)" "unprognostic (1.01e-1)" "unprognostic (8.96e-3)" "potential prognostic favorable (3.75e-8)" "unprognostic (2.69e-3)" "unprognostic (2.96e-2)" "unprognostic (1.26e-2)" "potential prognostic favorable (1.68e-4)" "unprognostic (2.31e-1)" "unprognostic (6.22e-2)" "unprognostic (7.85e-3)" "unprognostic (4.89e-2)" "unprognostic (2.00e-2)" "unprognostic (2.49e-2)" "unprognostic (4.65e-2)" "unprognostic (2.98e-1)" "unprognostic (1.54e-1)" "unprognostic (2.52e-2)" "unprognostic (5.16e-2)" "unprognostic (4.50e-2)" "unprognostic (2.14e-3)" "unprognostic (1.19e-1)" "unprognostic (8.01e-2)" "unprognostic (7.36e-3)" TMEM50A SMP1 ENSG00000183726 "Transmembrane protein 50A" O95807 1 25338317-25362361 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 835.2;Platelets: 1152.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065192 Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 47: Platelets - Hemostasis" 9 "Plasma membrane" "Actin filaments, Cytosol" "HPA065192: " "unprognostic (1.67e-2)" "unprognostic (1.53e-1)" "unprognostic (1.48e-3)" "unprognostic (3.54e-1)" "unprognostic (1.06e-2)" "unprognostic (5.76e-2)" "unprognostic (3.47e-1)" "unprognostic (1.55e-1)" "unprognostic (1.13e-1)" "unprognostic (1.71e-1)" "unprognostic (1.22e-3)" "unprognostic (1.71e-1)" "unprognostic (8.49e-2)" "validated prognostic unfavorable (1.64e-6)" "validated prognostic unfavorable (3.04e-4)" "unprognostic (9.35e-2)" "unprognostic (1.59e-1)" "unprognostic (1.97e-3)" "unprognostic (6.39e-2)" "unprognostic (1.64e-2)" "unprognostic (1.13e-1)" "unprognostic (3.45e-3)" "unprognostic (3.84e-1)" "unprognostic (1.43e-1)" "potential prognostic unfavorable (1.11e-4)" "unprognostic (7.41e-2)" "unprognostic (2.87e-1)" "unprognostic (9.27e-3)" "unprognostic (2.46e-1)" "unprognostic (1.56e-1)" "unprognostic (1.45e-1)" TMEM50B C21orf4 ENSG00000142188 "Transmembrane protein 50B" P56557 21 33432485-33479974 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 110.0;Early primary spermatocytes: 146.7;Late primary spermatocytes: 90.6;Oocytes: 124.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034199, HPA068995" Approved Approved "Nucleoli fibrillar center" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 22: Epididymis - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 102: Non-specific - Mixed function" 18 "Nucleoli fibrillar center" "CAB034199: , HPA068995: " "unprognostic (6.72e-3)" "unprognostic (2.78e-2)" "unprognostic (1.18e-1)" "unprognostic (2.97e-1)" "unprognostic (8.62e-3)" "unprognostic (9.65e-2)" "unprognostic (8.09e-2)" "unprognostic (5.13e-3)" "unprognostic (2.07e-1)" "unprognostic (6.66e-2)" "potential prognostic favorable (1.43e-8)" "unprognostic (1.84e-3)" "unprognostic (3.27e-2)" "unprognostic (2.50e-2)" "unprognostic (3.88e-3)" "potential prognostic favorable (2.79e-5)" "unprognostic (1.19e-1)" "unprognostic (4.20e-1)" "unprognostic (2.79e-1)" "unprognostic (4.09e-1)" "unprognostic (1.77e-1)" "unprognostic (3.00e-1)" "unprognostic (2.90e-2)" "unprognostic (3.12e-1)" "unprognostic (1.71e-2)" "unprognostic (1.28e-1)" "unprognostic (1.95e-2)" "unprognostic (4.30e-2)" "unprognostic (6.07e-2)" "unprognostic (1.19e-2)" "unprognostic (1.23e-2)" TMEM51 "C1orf72, FLJ10199" ENSG00000171729 "Transmembrane protein 51" Q9NW97 1 15152532-15220478 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 186.6;Epididymal clear cells: 316.4;Papillary tip epithelial cells: 192.6;Renal collecting duct intercalated cells: 293.3;Renal collecting duct principal cells: 186.6;Renal connecting tubule cells: 304.7;Salivary ionocytes: 187.5;Urothelial cells: 372.1" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 103.4;pericyte: 118.2;vascular associated smooth muscle cell: 150.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skeletal muscle - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014547, HPA019441" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 60: Stomach - Digestion" "Cluster 25: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 69: Urothelial cells - Basic cellular functions" 48 "Nucleoplasm, Cytosol" "HPA014547: , HPA019441: " "unprognostic (2.11e-1)" "unprognostic (1.84e-1)" "unprognostic (2.03e-2)" "unprognostic (1.65e-2)" "unprognostic (2.31e-1)" "potential prognostic unfavorable (6.32e-4)" "unprognostic (3.75e-2)" "unprognostic (2.79e-1)" "unprognostic (7.18e-2)" "unprognostic (1.29e-1)" "unprognostic (4.02e-3)" "unprognostic (3.04e-2)" "unprognostic (1.34e-3)" "unprognostic (3.35e-2)" "unprognostic (7.66e-2)" "unprognostic (2.10e-3)" "unprognostic (9.62e-3)" "unprognostic (4.86e-2)" "unprognostic (1.01e-1)" "unprognostic (1.31e-2)" "unprognostic (6.37e-2)" "unprognostic (1.11e-2)" "unprognostic (3.78e-1)" "unprognostic (2.39e-1)" "unprognostic (5.26e-2)" "unprognostic (3.10e-2)" "unprognostic (2.42e-1)" "unprognostic (3.21e-1)" "unprognostic (1.69e-1)" "unprognostic (1.11e-1)" "unprognostic (2.08e-1)" TMEM52 ENSG00000178821 "Transmembrane protein 52" Q8NDY8 1 1917590-1919279 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "pancreas: 206.6;skeletal muscle: 280.0;tongue: 193.9" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 41.2;Early primary spermatocytes: 49.8;Gastric chief cells: 30.6;Hepatocytes: 30.7;Myonuclei: 46.3;Oocytes: 46.1;Pancreatic acinar cells: 94.5;Thymic myoid cells: 115.6" "Cell type enhanced" "Detected in many" "ependymal cell: 7.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Lung - Respiratory ciliated cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Stomach - Chief cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA079372 Approved "Nucleoplasm,Plasma membrane" "Intracellular and membrane" "No annotated function" NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 17: Choroid plexus - Cilium" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 46: Skeletal myocytes - Muscle structure & formation" "Nucleoplasm, Plasma membrane" "HPA079372: " "unprognostic (3.03e-3)" "unprognostic (3.46e-1)" "unprognostic (5.35e-2)" "unprognostic (3.00e-1)" "unprognostic (2.40e-1)" "unprognostic (5.27e-2)" "unprognostic (1.50e-1)" "unprognostic (1.02e-2)" "unprognostic (2.11e-1)" "unprognostic (1.56e-2)" "unprognostic (5.05e-2)" "unprognostic (1.18e-2)" "unprognostic (2.11e-1)" "unprognostic (6.77e-2)" "unprognostic (5.72e-2)" "unprognostic (3.10e-1)" "unprognostic (5.99e-2)" "unprognostic (6.37e-3)" "unprognostic (1.22e-1)" "unprognostic (2.63e-2)" "unprognostic (2.58e-1)" "unprognostic (1.93e-2)" "unprognostic (3.96e-2)" "unprognostic (7.34e-2)" "unprognostic (1.72e-1)" "unprognostic (1.20e-1)" TMEM52B "C12orf59, FLJ31166" ENSG00000165685 "Transmembrane protein 52B" Q4KMG9 12 10170542-10191804 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "kidney: 105.7" "Group enriched" "Detected in some" 11 "Distal convoluted tubule cells: 1014.5;Epicardial cells: 725.5;Renal connecting tubule cells: 306.7" "Cell type enriched" "Detected in some" 13 "central nervous system macrophage: 23.5" "Cancer enriched" "Detected in many" 5 "Kidney Chromophobe (TCGA): 120.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 9.3" "Adrenal gland - Macrophages, Kidney - Intercalated cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA058096 Enhanced Approved "Focal adhesion sites" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 72: Kidney - Transmembrane transport" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 34: Testis cancer - Unknown function" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 59 "Focal adhesion sites" "HPA058096: " "unprognostic (1.09e-2)" "unprognostic (1.15e-2)" "unprognostic (2.09e-1)" "unprognostic (1.77e-1)" "unprognostic (6.08e-2)" "unprognostic (1.79e-3)" "unprognostic (8.34e-3)" "unprognostic (2.68e-2)" "unprognostic (1.21e-1)" "unprognostic (4.82e-2)" "unprognostic (1.68e-1)" "unprognostic (1.29e-1)" "unprognostic (1.37e-2)" "unprognostic (1.31e-1)" "potential prognostic favorable (4.65e-4)" TMEM53 "FLJ22353, NET4" ENSG00000126106 "Transmembrane protein 53" Q6P2H8 1 44635238-44674481 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" Dwarfism "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 56.1" "Cell type enriched" "Detected in many" 8 "Late spermatids: 1699.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "plasmacytoid DC: 99.6" "Lineage enriched" "Detected in all" 4 "dendritic cells: 99.6" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Liver - Hepatocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021134 Approved Approved "Golgi apparatus,Focal adhesion sites" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 47: Testis - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 6 "Golgi apparatus" "Focal adhesion sites" "HPA021134: " "unprognostic (2.10e-1)" "unprognostic (1.17e-1)" "unprognostic (3.80e-1)" "unprognostic (1.78e-1)" "unprognostic (7.71e-3)" "unprognostic (1.42e-1)" "unprognostic (1.42e-2)" "unprognostic (4.18e-2)" "unprognostic (5.68e-2)" "unprognostic (5.32e-2)" "unprognostic (1.17e-1)" "unprognostic (1.86e-1)" "unprognostic (2.43e-2)" "unprognostic (2.69e-3)" "unprognostic (3.02e-1)" "unprognostic (1.02e-3)" "unprognostic (1.60e-2)" "unprognostic (9.97e-3)" "unprognostic (2.27e-1)" "potential prognostic favorable (6.65e-4)" "unprognostic (1.18e-3)" "unprognostic (2.24e-1)" "unprognostic (7.30e-2)" "unprognostic (2.28e-1)" "unprognostic (1.88e-1)" "unprognostic (1.07e-1)" "unprognostic (3.92e-1)" "unprognostic (4.47e-2)" "unprognostic (2.30e-1)" "unprognostic (1.89e-2)" "unprognostic (3.61e-1)" TMEM54 "BCLP, CAC-1" ENSG00000121900 "Transmembrane protein 54" Q969K7 1 32894594-32901438 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 242.6" "Cell type enhanced" "Detected in many" "Colonocytes: 1522.0;Enteric transient amplifying cells: 343.5;Enterocytes: 376.2;Esophageal apical cells: 664.2;Esophageal suprabasal cells: 278.0;Foveolar cells: 335.0;Goblet cells: 314.6" "Cell type enhanced" "Detected in many" "ependymal cell: 21.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA060864, HPA061992" Approved Approved Vesicles NA NA "Cluster 77: Intestine - Digestion" "Cluster 39: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 19 Vesicles "HPA060864: , HPA061992: " "unprognostic (4.26e-2)" "unprognostic (3.02e-1)" "unprognostic (1.38e-1)" "unprognostic (8.01e-2)" "unprognostic (1.13e-1)" "unprognostic (1.92e-2)" "unprognostic (1.32e-2)" "potential prognostic unfavorable (5.59e-4)" "unprognostic (2.65e-2)" "unprognostic (6.12e-2)" "unprognostic (2.95e-1)" "unprognostic (2.29e-2)" "unprognostic (1.43e-1)" "potential prognostic unfavorable (8.28e-5)" "unprognostic (2.87e-3)" "unprognostic (1.36e-1)" "unprognostic (5.78e-2)" "unprognostic (2.85e-1)" "unprognostic (5.84e-2)" "unprognostic (6.68e-2)" "unprognostic (1.09e-1)" "unprognostic (6.20e-3)" "unprognostic (2.46e-2)" "unprognostic (2.69e-1)" "unprognostic (2.76e-1)" "unprognostic (8.80e-3)" "unprognostic (1.15e-1)" "unprognostic (4.12e-3)" "unprognostic (6.74e-2)" "unprognostic (5.19e-2)" "unprognostic (1.54e-2)" TMEM59 "C1orf8, HSPC001" ENSG00000116209 "Transmembrane protein 59" Q9BXS4 1 54026681-54053504 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 2658.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075447 Approved NA NA 7100 "Cluster 35: Neutrophils - Protein binding" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 37: Non-specific - mRNA processing" "Cluster 84: Apical squamous epithelium - Cornification" 46 "HPA075447: " "unprognostic (1.94e-1)" "unprognostic (2.38e-1)" "unprognostic (1.61e-1)" "unprognostic (1.45e-1)" "potential prognostic favorable (6.06e-4)" "unprognostic (9.11e-2)" "unprognostic (1.78e-1)" "unprognostic (1.81e-1)" "unprognostic (1.35e-1)" "unprognostic (7.76e-3)" "validated prognostic favorable (1.07e-8)" "validated prognostic favorable (4.39e-4)" "unprognostic (9.08e-2)" "unprognostic (2.63e-2)" "unprognostic (3.05e-1)" "unprognostic (7.16e-2)" "unprognostic (1.04e-1)" "unprognostic (1.58e-1)" "unprognostic (7.31e-2)" "unprognostic (2.61e-1)" "unprognostic (1.61e-1)" "unprognostic (2.11e-1)" "unprognostic (4.81e-3)" "unprognostic (2.66e-1)" "unprognostic (1.72e-1)" "unprognostic (5.42e-2)" "unprognostic (4.04e-1)" "unprognostic (6.68e-2)" "unprognostic (1.16e-1)" "unprognostic (2.83e-1)" "unprognostic (6.01e-2)" TMEM59L "BSMAP, C19orf4" ENSG00000105696 "Transmembrane protein 59 like" Q9UK28 19 18607430-18621039 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 342.8" "Cell type enhanced" "Detected in some" "Astrocytes: 43.0;Bergmann glia: 37.7;Brain excitatory neurons: 194.4;Brain inhibitory neurons: 169.3;Ependymal cells: 56.6;Müller glia: 67.7;Oligodendrocyte progenitor cells: 71.5;Other brain neurons: 246.9;Retinal amacrine cells: 56.6;Retinal bipolar cells: 53.1" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 5 "Glioblastoma Multiforme (TCGA): 118.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 25.9" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010661 Approved NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 14: Neurons - Synaptic function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 98: Neurons - Neurotransmission & signaling" 14 "HPA010661: " "unprognostic (2.57e-1)" "unprognostic (2.53e-2)" "unprognostic (2.57e-1)" "unprognostic (1.68e-2)" "unprognostic (4.19e-2)" "unprognostic (2.36e-1)" "potential prognostic unfavorable (2.46e-5)" "unprognostic (5.63e-2)" "unprognostic (2.84e-1)" "unprognostic (5.31e-3)" "unprognostic (1.90e-3)" "unprognostic (2.00e-1)" "unprognostic (1.39e-2)" "unprognostic (1.19e-1)" "unprognostic (4.95e-3)" "unprognostic (2.04e-1)" "unprognostic (1.09e-1)" "unprognostic (1.23e-2)" TMEM60 "C7orf35, DC32" ENSG00000135211 "Transmembrane protein 60" Q9H2L4 7 77793728-77798434 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 100.3;Hofbauer cells: 104.9;Oocytes: 105.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062625 Approved NA Yes "Cluster 42: Non-specific - Vesicular transport" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 39: Non-specific - Transcription" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 86 "HPA062625: " "unprognostic (1.63e-1)" "unprognostic (1.27e-2)" "unprognostic (8.17e-2)" "unprognostic (4.15e-1)" "unprognostic (1.71e-1)" "unprognostic (7.19e-2)" "potential prognostic unfavorable (1.95e-4)" "unprognostic (5.32e-3)" "unprognostic (9.30e-2)" "unprognostic (1.58e-1)" "unprognostic (1.21e-3)" "unprognostic (3.17e-1)" "unprognostic (1.75e-1)" "unprognostic (1.97e-3)" "potential prognostic unfavorable (4.19e-5)" "unprognostic (2.41e-1)" "unprognostic (1.13e-1)" "unprognostic (1.84e-2)" "unprognostic (2.55e-2)" "unprognostic (2.58e-2)" "unprognostic (1.53e-1)" "unprognostic (7.38e-2)" "unprognostic (1.01e-1)" "unprognostic (6.25e-2)" "unprognostic (1.84e-1)" "unprognostic (2.19e-1)" "unprognostic (4.38e-2)" "unprognostic (1.29e-2)" "unprognostic (1.01e-2)" "unprognostic (2.30e-2)" "unprognostic (1.43e-1)" TMEM61 ENSG00000143001 "Transmembrane protein 61" Q8N0U2 1 54980628-54992288 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 16.1;pituitary gland: 38.2;salivary gland: 18.4" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 50.5;Corticotrophs: 70.8;Epididymal clear cells: 87.8;Goblet cells: 63.5;Pancreatic islet cells: 42.1;Respiratory ionocytes: 355.6;Salivary duct cells: 54.3;Salivary ionocytes: 219.3;Salivary myoepithelial cells: 42.3" "Cell type enhanced" "Detected in some" "cerebellar inhibitory: 9.8;lower rhombic lip: 12.7;upper rhombic lip: 6.9" "Cancer enriched" "Detected in many" 7 "Kidney Chromophobe (TCGA): 38.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 3.4;pancreatic cancer: 3.6" "Adipose subcutaneous - Smooth muscle cells, Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Corticotropes" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA030614, HPA057087" Uncertain Approved "Vesicles,Plasma membrane" NA NA "Cluster 20: Pituitary gland - Hormone signaling" "Cluster 49: Hindbrain - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 11 "Plasma membrane" Vesicles "HPA030614: , HPA057087: " "unprognostic (2.69e-3)" "unprognostic (2.88e-1)" "unprognostic (2.76e-3)" "unprognostic (1.05e-1)" "potential prognostic favorable (8.35e-4)" "unprognostic (2.23e-2)" "unprognostic (1.10e-1)" "unprognostic (1.69e-2)" "unprognostic (1.82e-2)" "unprognostic (2.02e-1)" "unprognostic (6.54e-2)" "unprognostic (1.40e-2)" "unprognostic (6.08e-2)" "unprognostic (1.55e-1)" "unprognostic (4.95e-3)" "unprognostic (8.24e-2)" "unprognostic (2.88e-2)" "unprognostic (5.11e-2)" "unprognostic (2.60e-3)" "unprognostic (1.78e-1)" "unprognostic (1.50e-2)" TMEM62 FLJ23375 ENSG00000137842 "Transmembrane protein 62" Q0P6H9 15 43123279-43185144 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044461, HPA062359" Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Nuclear bodies,Cytoplasmic bodies" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 17: Intestine - Digestion" "Cluster 2: Neurons - Nucleosome" "Cluster 27: Breast cancer - Unknown function" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 1 "Nucleoplasm, Nucleoli fibrillar center, Nuclear bodies, Cytoplasmic bodies" "HPA044461: , HPA062359: " "unprognostic (3.31e-1)" "unprognostic (3.49e-3)" "unprognostic (1.69e-1)" "unprognostic (1.50e-1)" "unprognostic (2.52e-2)" "unprognostic (3.35e-2)" "unprognostic (3.34e-1)" "unprognostic (1.58e-2)" "unprognostic (4.28e-1)" "unprognostic (1.11e-1)" "potential prognostic favorable (1.61e-10)" "unprognostic (8.47e-2)" "unprognostic (1.03e-1)" "unprognostic (1.87e-1)" "unprognostic (2.83e-2)" "unprognostic (1.38e-1)" "unprognostic (1.07e-1)" "unprognostic (4.70e-2)" "unprognostic (2.67e-1)" "unprognostic (2.45e-1)" "unprognostic (4.35e-3)" "unprognostic (2.62e-3)" "unprognostic (6.76e-3)" "unprognostic (1.50e-1)" "unprognostic (4.69e-2)" "unprognostic (2.83e-2)" "unprognostic (7.99e-3)" "unprognostic (6.50e-2)" "unprognostic (5.12e-2)" "unprognostic (3.07e-2)" "unprognostic (2.31e-1)" TMEM63A KIAA0792 ENSG00000196187 "Transmembrane protein 63A" O94886 1 225845536-225882380 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 153.0" "Cell type enhanced" "Detected in many" "Lacrimal acinar cells: 190.2;Neutrophil progenitors: 158.1;Oligodendrocytes: 228.8;Tuft cells: 311.3" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 126.6;oligodendrocyte: 309.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066504, HPA066936, HPA068918" Enhanced "Vesicles,Centriolar satellite" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 27: Breast cancer - Unknown function" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 24 "Vesicles, Centriolar satellite" "HPA066504: , HPA066936: , HPA068918: " "unprognostic (1.06e-1)" "unprognostic (7.96e-2)" "unprognostic (2.46e-2)" "unprognostic (1.51e-3)" "unprognostic (2.79e-1)" "unprognostic (1.02e-1)" "unprognostic (1.56e-1)" "unprognostic (5.31e-2)" "unprognostic (8.30e-2)" "unprognostic (3.59e-1)" "unprognostic (1.68e-3)" "unprognostic (2.26e-2)" "unprognostic (2.29e-2)" "unprognostic (8.00e-2)" "unprognostic (2.85e-2)" "unprognostic (1.29e-3)" "unprognostic (2.83e-2)" "unprognostic (6.59e-3)" "unprognostic (5.95e-2)" "unprognostic (2.35e-1)" "unprognostic (1.41e-1)" "unprognostic (2.63e-2)" "unprognostic (3.57e-1)" "unprognostic (4.05e-1)" "unprognostic (2.04e-1)" "unprognostic (2.29e-3)" "unprognostic (3.81e-2)" "unprognostic (3.13e-2)" "unprognostic (1.88e-1)" "unprognostic (1.22e-1)" "unprognostic (2.45e-1)" TMEM63B "C6orf110, dJ421H19.2, DKFZp434P0531" ENSG00000137216 "Transmembrane protein 63B" Q5T3F8 6 44126914-44155519 "Predicted membrane proteins, Transporters" "Exocytosis, Hearing, Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 153.5;Late spermatids: 141.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029249, HPA029250, HPA029251" Uncertain Enhanced "Plasma membrane,Actin filaments" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 81: Alveolar cells - Lung function" 9 "Plasma membrane, Actin filaments" "HPA029249: , HPA029250: , HPA029251: " "unprognostic (1.85e-1)" "unprognostic (6.08e-3)" "unprognostic (8.99e-2)" "unprognostic (1.65e-1)" "unprognostic (1.24e-1)" "unprognostic (5.88e-2)" "unprognostic (3.98e-1)" "unprognostic (2.91e-1)" "unprognostic (1.95e-1)" "unprognostic (1.14e-1)" "unprognostic (5.13e-2)" "unprognostic (1.11e-1)" "unprognostic (1.67e-1)" "unprognostic (7.74e-3)" "unprognostic (7.26e-2)" "unprognostic (6.99e-3)" "unprognostic (6.66e-2)" "unprognostic (7.84e-2)" "unprognostic (2.58e-2)" "unprognostic (3.18e-1)" "unprognostic (2.26e-1)" "unprognostic (3.31e-2)" "unprognostic (1.78e-1)" "unprognostic (2.87e-1)" "unprognostic (3.11e-2)" "unprognostic (2.48e-2)" "unprognostic (4.42e-1)" "unprognostic (1.78e-1)" "unprognostic (7.06e-2)" "unprognostic (2.68e-2)" "unprognostic (4.63e-2)" TMEM63C "C14orf171, CSC1, DKFZp434P0111, hsCSC1" ENSG00000165548 "Transmembrane protein 63C" Q9P1W3 14 77116568-77259495 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 53.9;pituitary gland: 39.9" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 21.3;Brain excitatory neurons: 23.9;Brain inhibitory neurons: 17.9;Corticotrophs: 26.6;Gonadotrophs: 37.5;Lactotrophs: 38.3;Neuroendocrine cells: 21.4;Oligodendrocyte progenitor cells: 18.5;Other brain neurons: 23.8;Pancreatic islet cells: 17.5;Retinal ganglion cells: 34.8;Retinal pigment epithelial cells: 25.6;Somatotrophs: 27.8;Thyrotrophs: 35.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 14.8" "Breast - Breast glandular cells, Breast - Breast glandular cells, Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Liver - Kupffer cells, Minor Salivary Gland - Minor salivary gland basal cells, Pancreas - Alpha cells, Pancreas - Beta cells, Spleen - Macrophages, Stomach - Gastric enteroendocrine cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030657 Uncertain Approved Centrosome NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 1: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" Centrosome "HPA030657: " "unprognostic (5.91e-2)" "unprognostic (3.94e-1)" "unprognostic (1.05e-1)" "unprognostic (1.78e-1)" "unprognostic (7.72e-2)" "unprognostic (1.68e-2)" "unprognostic (2.84e-1)" "unprognostic (4.30e-3)" "unprognostic (6.34e-2)" "unprognostic (2.02e-1)" "unprognostic (1.54e-2)" "unprognostic (6.89e-3)" "unprognostic (1.13e-1)" "unprognostic (5.03e-2)" "unprognostic (1.49e-2)" "unprognostic (1.51e-2)" "unprognostic (7.08e-2)" "unprognostic (2.11e-3)" "unprognostic (2.05e-2)" "unprognostic (1.64e-1)" "unprognostic (5.87e-3)" "unprognostic (1.27e-1)" "unprognostic (6.58e-2)" "potential prognostic unfavorable (9.15e-7)" "potential prognostic unfavorable (2.92e-4)" TMEM64 DKFZp762C1112 ENSG00000180694 "Transmembrane protein 64" Q6YI46 8 90621995-90791632 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "epididymis: 136.8" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 229.7;Epididymal principal cells: 428.2;Oligodendrocytes: 108.2;Platelets: 135.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Smooth muscle cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB034221 Uncertain NA NA "Cluster 24: Non-specific - Transcription" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 36: Choroid plexus - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" "CAB034221: " "potential prognostic favorable (2.24e-4)" "unprognostic (7.36e-2)" "unprognostic (4.34e-1)" "unprognostic (8.22e-2)" "unprognostic (9.14e-2)" "unprognostic (1.05e-2)" "unprognostic (2.30e-1)" "unprognostic (7.19e-2)" "unprognostic (2.39e-1)" "potential prognostic unfavorable (8.16e-5)" "potential prognostic favorable (5.73e-5)" "unprognostic (2.37e-2)" "unprognostic (3.55e-1)" "unprognostic (5.31e-3)" "unprognostic (1.65e-1)" "unprognostic (3.30e-3)" "unprognostic (1.08e-1)" "unprognostic (4.78e-2)" "unprognostic (2.80e-1)" "unprognostic (2.45e-3)" "unprognostic (1.27e-2)" "unprognostic (1.06e-1)" "unprognostic (2.30e-2)" "unprognostic (6.77e-2)" "unprognostic (2.53e-1)" "unprognostic (2.04e-1)" "unprognostic (6.94e-2)" "unprognostic (9.56e-2)" "unprognostic (2.98e-2)" "unprognostic (2.51e-1)" "unprognostic (2.99e-2)" TMEM65 ENSG00000164983 "Transmembrane protein 65" Q6PI78 8 124306189-124372701 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 391.5;Myonuclei: 440.0;Neutrophils: 304.8;Pituitary stem cells: 239.6;Retinal horizontal cells: 342.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Vascular endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007108, HPA025020" Uncertain Supported "Vesicles,Plasma membrane" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 55: Myocytes - Oxidative muscle function" 29 "Vesicles, Plasma membrane" "HPA007108: , HPA025020: " "unprognostic (2.94e-2)" "unprognostic (2.17e-3)" "unprognostic (2.55e-2)" "unprognostic (7.42e-3)" "unprognostic (2.52e-1)" "unprognostic (1.87e-3)" "unprognostic (1.31e-1)" "unprognostic (2.40e-1)" "unprognostic (7.20e-2)" "unprognostic (4.42e-2)" "unprognostic (2.48e-3)" "unprognostic (4.41e-2)" "unprognostic (1.92e-1)" "potential prognostic unfavorable (8.33e-5)" "unprognostic (9.46e-3)" "unprognostic (1.85e-3)" "unprognostic (1.22e-2)" "unprognostic (3.52e-2)" "unprognostic (1.14e-1)" "unprognostic (2.61e-1)" "unprognostic (3.87e-2)" "unprognostic (4.80e-2)" "potential prognostic unfavorable (7.74e-4)" "unprognostic (3.81e-2)" "unprognostic (2.04e-1)" "unprognostic (1.23e-2)" "unprognostic (1.12e-1)" "unprognostic (5.41e-2)" "unprognostic (5.92e-2)" "unprognostic (4.74e-2)" "unprognostic (1.63e-1)" TMEM67 "JBTS6, MGC26979, MKS3, NPHP11" ENSG00000164953 "Transmembrane protein 67" Q5HYA8 8 93754844-93819234 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cilium biogenesis/degradation" "Bardet-Biedl syndrome, Ciliopathy, Deafness, Disease variant, Intellectual disability, Joubert syndrome, Meckel syndrome, Nephronophthisis, Obesity, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 20.8" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 215.5;Ependymal cells: 532.9;Epididymal efferent duct ciliated cells: 144.8;Fallopian tube ciliated cells: 202.1;Respiratory ciliated cells: 327.8" "Cell type enhanced" "Detected in all" "ependymal cell: 599.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Vascular endothelial cells, Lung - Respiratory ciliated cells, Spleen - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 35: Non-specific - Mixed function" "Cluster 17: Choroid plexus - Cilium" "Cluster 69: Skin cancer - ECM organization" "Cluster 34: Ciliated cells - Cilia assembly & function" 30 "unprognostic (1.94e-1)" "unprognostic (3.42e-3)" "unprognostic (1.92e-1)" "unprognostic (3.84e-1)" "unprognostic (4.41e-1)" "unprognostic (2.85e-1)" "unprognostic (1.01e-1)" "unprognostic (2.21e-1)" "unprognostic (6.55e-3)" "potential prognostic unfavorable (5.32e-4)" "unprognostic (5.45e-2)" "unprognostic (7.88e-2)" "unprognostic (1.49e-1)" "unprognostic (1.10e-1)" "unprognostic (2.17e-1)" "unprognostic (8.79e-2)" "unprognostic (2.37e-1)" "unprognostic (1.07e-1)" "validated prognostic unfavorable (6.06e-6)" "validated prognostic unfavorable (1.52e-4)" "unprognostic (1.59e-1)" "unprognostic (1.13e-3)" "unprognostic (2.63e-2)" "unprognostic (3.88e-2)" "unprognostic (1.65e-2)" "unprognostic (2.76e-1)" "unprognostic (5.83e-2)" "unprognostic (3.11e-1)" "unprognostic (2.71e-3)" "unprognostic (1.39e-2)" TMEM68 FLJ32370 ENSG00000167904 "Transmembrane protein 68" Q96MH6 8 55696424-55773407 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fallopian tube ciliated cells: 103.7;Respiratory ciliated cells: 96.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018216, HPA019173" Uncertain Approved Vesicles NA NA "Cluster 24: Non-specific - Transcription" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 31: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 107: Ciliated cells - Cilia assembly & function" 8 Vesicles "HPA018216: , HPA019173: " "unprognostic (9.11e-3)" "unprognostic (1.14e-2)" "unprognostic (1.56e-1)" "unprognostic (1.08e-2)" "unprognostic (1.89e-1)" "unprognostic (8.02e-2)" "unprognostic (4.02e-2)" "unprognostic (1.30e-1)" "unprognostic (7.13e-2)" "unprognostic (5.23e-2)" "unprognostic (3.51e-3)" "unprognostic (3.08e-2)" "unprognostic (1.71e-1)" "unprognostic (1.45e-3)" "unprognostic (4.16e-3)" "unprognostic (1.78e-1)" "unprognostic (1.56e-1)" "unprognostic (9.86e-2)" "unprognostic (5.79e-2)" "unprognostic (8.27e-2)" "unprognostic (1.15e-2)" "unprognostic (4.43e-3)" "unprognostic (1.39e-3)" "unprognostic (1.45e-1)" "unprognostic (1.53e-1)" "unprognostic (2.04e-1)" "unprognostic (5.58e-2)" "unprognostic (2.22e-2)" "unprognostic (3.66e-1)" "unprognostic (7.19e-2)" "unprognostic (9.48e-2)" TMEM69 "C1orf154, FLJ21029" ENSG00000159596 "Transmembrane protein 69" Q5SWH9 1 45688181-45694436 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 72.2;Migrating cytotrophoblasts: 71.6;Oocytes: 193.4;Syncytiotrophoblasts: 72.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026993 Approved Approved Nucleoplasm NA NA "Cluster 18: Non-specific - Translation" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 37: Non-specific - mRNA processing" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 14 Nucleoplasm "HPA026993: " "unprognostic (6.99e-2)" "unprognostic (2.77e-2)" "unprognostic (1.79e-2)" "unprognostic (1.53e-1)" "unprognostic (1.93e-2)" "unprognostic (7.88e-2)" "unprognostic (2.03e-1)" "unprognostic (5.11e-2)" "unprognostic (8.90e-2)" "unprognostic (1.19e-1)" "unprognostic (6.27e-2)" "unprognostic (3.26e-1)" "unprognostic (9.74e-2)" "validated prognostic unfavorable (8.10e-10)" "validated prognostic unfavorable (7.16e-4)" "unprognostic (3.56e-2)" "unprognostic (6.59e-3)" "unprognostic (8.46e-3)" "unprognostic (1.28e-1)" "unprognostic (1.24e-1)" "unprognostic (2.66e-1)" "unprognostic (2.43e-3)" "unprognostic (7.17e-2)" "unprognostic (1.98e-1)" "unprognostic (4.53e-2)" "unprognostic (1.66e-1)" "unprognostic (9.05e-3)" "unprognostic (4.92e-2)" "unprognostic (2.35e-1)" "unprognostic (1.03e-1)" "unprognostic (1.26e-1)" TMEM70 FLJ20533 ENSG00000175606 "Transmembrane protein 70" Q9BUB7 8 73972437-73982783 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "skeletal muscle: 95.2" "Cell type enhanced" "Detected in many" "Hofbauer cells: 137.0;Parietal cells: 185.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023187, CAB034226" Approved Supported Nucleoplasm,Mitochondria NA Yes "Cluster 45: Eosinophils - Unknown function" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 31: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 16 Mitochondria Nucleoplasm "CAB034226: , HPA023187: " "unprognostic (1.83e-1)" "potential prognostic unfavorable (2.12e-4)" "unprognostic (7.64e-2)" "unprognostic (1.18e-3)" "potential prognostic favorable (2.98e-4)" "unprognostic (2.88e-1)" "unprognostic (1.54e-3)" "unprognostic (1.45e-2)" "unprognostic (5.36e-2)" "unprognostic (9.83e-2)" "unprognostic (1.52e-1)" "potential prognostic unfavorable (7.67e-4)" "unprognostic (3.19e-1)" "unprognostic (1.97e-1)" "unprognostic (1.92e-1)" "unprognostic (5.90e-2)" "unprognostic (1.34e-2)" "unprognostic (1.16e-2)" "unprognostic (1.64e-1)" "unprognostic (2.14e-1)" "unprognostic (1.17e-1)" "unprognostic (1.95e-2)" "potential prognostic unfavorable (2.55e-5)" "unprognostic (3.03e-1)" "unprognostic (2.62e-1)" "unprognostic (1.32e-1)" "unprognostic (1.28e-2)" "unprognostic (2.23e-1)" "unprognostic (8.21e-3)" "unprognostic (1.55e-2)" "unprognostic (1.32e-1)" TMEM71 FLJ33069 ENSG00000165071 "Transmembrane protein 71" Q6P5X7 8 132685007-132760712 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 31.6;heart muscle: 34.7" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 326.0;Monocyte progenitors: 100.7;monocytes: 124.5;Neutrophil progenitors: 280.5;Neutrophils: 1033.9;NK-cells: 149.5;T-cells: 109.6" "Cell type enhanced" "Detected in some" "fibroblast: 56.2;leukocyte: 177.7" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 4 "cerebral cortex: 20.8" "Immune cell enhanced" "Detected in all" "neutrophil: 270.6" "Lineage enriched" "Detected in all" 5 "granulocytes: 270.6" "Cancer enhanced" "Detected in many" "Bone cancer: 9.1;Leukemia: 8.0" "Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Lung - NK-cells (Lung), Spleen - Neutrophils_2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA058401, HPA070655" Uncertain Enhanced Mitochondria NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 35: Non-specific - Mixed function" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" Mitochondria "HPA058401: , HPA070655: " "unprognostic (1.06e-1)" "potential prognostic favorable (3.51e-4)" "unprognostic (3.59e-2)" "unprognostic (6.10e-2)" "unprognostic (2.49e-1)" "unprognostic (3.71e-3)" "unprognostic (3.43e-2)" "unprognostic (1.29e-3)" "unprognostic (1.31e-2)" "unprognostic (5.16e-2)" "unprognostic (2.40e-1)" "potential prognostic favorable (2.25e-4)" "unprognostic (3.49e-2)" "unprognostic (1.38e-3)" "unprognostic (1.12e-1)" "unprognostic (2.42e-1)" "unprognostic (9.56e-2)" "unprognostic (1.83e-1)" "unprognostic (2.04e-1)" "unprognostic (1.85e-1)" "unprognostic (1.13e-2)" "unprognostic (2.22e-1)" "unprognostic (8.95e-2)" "unprognostic (1.78e-1)" "unprognostic (2.45e-2)" "unprognostic (4.03e-2)" "unprognostic (6.92e-2)" TMEM72 "bA285G1.3, C10orf127, KSP37" ENSG00000187783 "Transmembrane protein 72" A0PK05 10 44911316-44937010 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "choroid plexus: 45.3;kidney: 76.7" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 139.9;Colonocytes: 27.9;Distal convoluted tubule cells: 208.7;Late spermatids: 57.9;Loop of henle epithelial cells: 121.5;Renal collecting duct intercalated cells: 78.1;Renal collecting duct principal cells: 37.8;Renal connecting tubule cells: 124.9;Retinal pigment epithelial cells: 85.3" "Cell type enriched" "Detected in some" 4 "choroid plexus epithelial cell: 93.9" "Cancer enriched" "Detected in some" 5 "Kidney Chromophobe (TCGA): 64.4" "Region enriched" "Detected in all" 13 "choroid plexus: 112.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "Myeloma: 3.7" "Colon - Colon enterocytes, Kidney - Ascending Loop of Henle cells, Testis - Late spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA039894, HPA062907" Enhanced NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 32 "HPA039894: , HPA062907: " "unprognostic (1.69e-2)" "unprognostic (1.43e-1)" "potential prognostic favorable (4.08e-5)" "unprognostic (1.17e-3)" "unprognostic (6.61e-2)" "unprognostic (3.05e-2)" "unprognostic (1.65e-2)" TMEM74 "FLJ30668, NET36" ENSG00000164841 "Transmembrane protein 74" Q96NL1 8 108606850-108787594 "Predicted membrane proteins, Transporters" Autophagy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.7;retina: 2.3" "Group enriched" "Detected in many" 8 "Bergmann glia: 64.2;Epididymal principal cells: 191.8" "Cell type enhanced" "Detected in many" "Bergmann glia: 73.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 1.2" "Colon - Enteric glia cells, Stomach - Fibroblasts, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015672, HPA076461" Uncertain Approved "Golgi apparatus,Cytosol" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 55: Non-specific - Transcription" "Cluster 11: Neuronal - Sensory perception" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 6 "Golgi apparatus, Cytosol" "HPA015672: , HPA076461: " "unprognostic (1.62e-2)" "unprognostic (2.65e-1)" TMEM74B "C20orf46, FLJ11190" ENSG00000125895 "Transmembrane protein 74B" Q9NUR3 20 1180561-1185415 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.3;lung: 23.0" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 27.2;Breast lactating cells: 11.6;Enterocytes: 18.1;Fallopian tube ciliated cells: 23.1;Goblet cells: 18.5;Gonadotrophs: 17.6;Neuroendocrine cells: 17.9;Other brain neurons: 18.1;Pancreatic islet cells: 13.2;Parietal cells: 14.1;Pericytes: 20.8;Retinal ganglion cells: 27.0;Retinal horizontal cells: 12.0;Tuft cells: 46.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045213 Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 24: Neurons - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 110: Mural cells - ECM organization" "Nucleoplasm, Golgi apparatus" "HPA045213: " "unprognostic (2.81e-2)" "unprognostic (6.47e-2)" "unprognostic (3.36e-2)" "unprognostic (1.63e-1)" "unprognostic (2.13e-2)" "unprognostic (1.02e-1)" "unprognostic (4.19e-2)" "unprognostic (8.14e-2)" "unprognostic (8.84e-2)" "potential prognostic unfavorable (1.03e-5)" "unprognostic (3.66e-2)" "unprognostic (1.47e-1)" "unprognostic (2.19e-2)" "unprognostic (1.90e-1)" "unprognostic (4.75e-2)" "unprognostic (1.75e-1)" "unprognostic (1.61e-1)" "unprognostic (7.90e-2)" "unprognostic (3.85e-1)" "potential prognostic favorable (4.92e-5)" "potential prognostic unfavorable (6.19e-4)" "unprognostic (1.03e-1)" "unprognostic (1.08e-2)" "unprognostic (7.56e-2)" "unprognostic (8.55e-2)" "unprognostic (1.72e-1)" "unprognostic (2.01e-1)" "unprognostic (4.70e-2)" TMEM79 "FLJ16057, FLJ32254, MATT, MGC13102" ENSG00000163472 "Transmembrane protein 79" Q9BSE2 1 156282935-156293185 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 136.8;skin 1: 88.6;vagina: 59.1" "Group enriched" "Detected in many" 4 "Esophageal apical cells: 1075.4;Esophageal suprabasal cells: 348.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Head and Neck Squamous Cell Carcinoma (TCGA): 58.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA055214 Enhanced Approved "Nucleoli fibrillar center" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 41 "Nucleoli fibrillar center" "HPA055214: " "unprognostic (1.78e-1)" "unprognostic (2.23e-1)" "unprognostic (4.46e-2)" "unprognostic (2.79e-1)" "unprognostic (5.36e-2)" "unprognostic (1.26e-1)" "unprognostic (7.06e-2)" "unprognostic (4.02e-1)" "unprognostic (4.37e-2)" "unprognostic (2.14e-1)" "unprognostic (5.24e-2)" "unprognostic (2.16e-3)" "unprognostic (1.04e-2)" "potential prognostic unfavorable (3.63e-6)" "unprognostic (1.54e-1)" "unprognostic (1.71e-2)" "unprognostic (2.07e-2)" "unprognostic (3.17e-1)" "unprognostic (3.23e-2)" "unprognostic (8.73e-2)" "unprognostic (4.21e-1)" "unprognostic (1.24e-1)" "unprognostic (1.76e-2)" "unprognostic (6.25e-3)" "unprognostic (2.13e-1)" "unprognostic (1.93e-2)" "unprognostic (2.05e-1)" "unprognostic (3.81e-2)" "unprognostic (3.41e-1)" "unprognostic (3.14e-2)" "unprognostic (1.81e-1)" TMEM80 FLJ38216 ENSG00000177042 "Transmembrane protein 80" Q96HE8 11 695591-705028 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 36.3;Early primary spermatocytes: 66.9;Esophageal apical cells: 30.5;Late primary spermatocytes: 13.0;Oocytes: 23.0;Undifferentiated spermatogonia: 15.2" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059592, HPA067046" Uncertain Approved "Golgi apparatus" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 70: DU4475 - Unknown function" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 53 "Golgi apparatus" "HPA059592: , HPA067046: " "unprognostic (1.87e-3)" "unprognostic (4.02e-2)" "unprognostic (1.46e-1)" "unprognostic (3.70e-1)" "unprognostic (7.93e-3)" "unprognostic (2.65e-2)" "unprognostic (2.49e-2)" "unprognostic (2.68e-1)" "unprognostic (1.80e-3)" "unprognostic (1.21e-1)" "unprognostic (1.76e-3)" "unprognostic (4.58e-2)" "unprognostic (1.21e-3)" "unprognostic (1.28e-1)" "unprognostic (4.83e-2)" "unprognostic (1.28e-1)" "unprognostic (4.15e-3)" "unprognostic (9.34e-2)" "unprognostic (1.12e-2)" "unprognostic (1.08e-1)" "unprognostic (1.11e-1)" "potential prognostic favorable (4.43e-4)" "unprognostic (5.75e-2)" "unprognostic (2.61e-1)" "unprognostic (1.61e-1)" "unprognostic (3.25e-2)" "unprognostic (6.38e-2)" "unprognostic (6.63e-2)" "unprognostic (1.62e-1)" "unprognostic (1.93e-1)" "unprognostic (1.07e-1)" TMEM81 "HC3107, KVLA2788, MGC75217, UNQ2788" ENSG00000174529 "Transmembrane protein 81" Q6P7N7 1 205083129-205084460 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 15.7" "Cell type enhanced" "Detected in some" "Early spermatids: 12.3;Late primary spermatocytes: 14.7;Paneth cells: 7.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA052515 Approved "Intermediate filaments" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 71: Cerebellum - Nervous system development" "Cluster 2: Neurons - Nucleosome" "Cluster 45: Non-specific - Nuclear processes" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" "Intermediate filaments" "HPA052515: " "unprognostic (9.95e-3)" "unprognostic (1.05e-2)" "unprognostic (9.00e-2)" "unprognostic (1.78e-1)" "unprognostic (3.46e-2)" "unprognostic (1.16e-1)" "unprognostic (2.20e-1)" "unprognostic (1.27e-1)" "unprognostic (4.41e-2)" "unprognostic (8.28e-2)" "potential prognostic unfavorable (5.88e-7)" "unprognostic (1.74e-1)" "unprognostic (5.30e-2)" "potential prognostic unfavorable (4.24e-7)" "unprognostic (1.73e-1)" "unprognostic (3.20e-3)" "unprognostic (2.13e-3)" "unprognostic (8.01e-2)" "unprognostic (1.17e-1)" "unprognostic (1.44e-1)" "unprognostic (3.72e-2)" "unprognostic (5.13e-2)" "unprognostic (5.44e-2)" "unprognostic (5.38e-2)" "unprognostic (2.64e-2)" "unprognostic (2.49e-2)" "unprognostic (2.68e-1)" "unprognostic (6.75e-2)" "unprognostic (6.07e-2)" "unprognostic (9.47e-2)" "unprognostic (1.65e-1)" TMEM82 ENSG00000162460 "Transmembrane protein 82" A0PJX8 1 15742499-15747982 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 22.9;kidney: 12.0;liver: 55.1" "Group enriched" "Detected in some" 4 "Colonocytes: 51.2;Enterocytes: 176.4;Hepatocytes: 61.8" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney Renal Papillary Cell Carcinoma (TCGA): 17.5;Liver Hepatocellular Carcinoma (TCGA): 13.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA060282 Uncertain Uncertain Nucleoplasm,Cytosol NA NA "Cluster 77: Intestine - Digestion" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" Nucleoplasm Cytosol "HPA060282: " "unprognostic (1.05e-1)" "unprognostic (1.41e-1)" "unprognostic (1.01e-1)" "potential prognostic favorable (9.85e-9)" "unprognostic (3.19e-2)" "potential prognostic favorable (1.08e-4)" "unprognostic (4.73e-3)" "unprognostic (4.74e-2)" "unprognostic (4.57e-3)" "unprognostic (3.12e-1)" "unprognostic (3.64e-1)" TMEM86A FLJ90119 ENSG00000151117 "Transmembrane protein 86A" Q8N2M4 11 18693122-18704785 "Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 17.2" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 24.7;Hofbauer cells: 67.0;Kupffer cells: 27.7;Late primary spermatocytes: 18.6;Late spermatids: 20.1;Microglia: 12.4;Retinal pigment epithelial cells: 17.1;Salivary ionocytes: 16.6" "Cell type enriched" "Detected in many" 5 "central nervous system macrophage: 14.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 3.4" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "breast cancer: 11.4" "Colon - Macrophages, Lung - Macrophages, Minor Salivary Gland - Macrophages, Prostate - Macrophages, Skin - Keratinocyte (granular), Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057119 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 58: Skin - Keratinization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 27: Breast cancer - Unknown function" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 38 "Nucleoplasm, Golgi apparatus" "HPA057119: " "unprognostic (2.23e-1)" "unprognostic (1.54e-1)" "unprognostic (1.40e-1)" "unprognostic (2.20e-2)" "unprognostic (3.65e-3)" "unprognostic (1.46e-1)" "unprognostic (1.89e-1)" "unprognostic (1.12e-3)" "unprognostic (4.98e-2)" "unprognostic (2.73e-1)" "unprognostic (2.97e-2)" "unprognostic (1.32e-1)" "unprognostic (1.07e-2)" "unprognostic (1.50e-1)" "unprognostic (5.10e-3)" "unprognostic (1.76e-1)" "unprognostic (1.03e-2)" "unprognostic (3.69e-2)" "unprognostic (7.64e-2)" "unprognostic (2.40e-1)" "unprognostic (3.83e-2)" "unprognostic (1.90e-1)" "unprognostic (9.54e-2)" "unprognostic (9.60e-2)" "unprognostic (7.28e-2)" "unprognostic (1.98e-1)" "unprognostic (1.64e-1)" "unprognostic (2.50e-2)" "unprognostic (7.29e-2)" "unprognostic (1.24e-1)" "unprognostic (1.41e-1)" TMEM86B MGC30208 ENSG00000180089 "Transmembrane protein 86B" Q8N661 19 55226638-55228784 "Enzymes, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 47.0" "Cell type enhanced" "Detected in many" "Cholangiocytes: 28.3;Erythrocyte progenitors: 25.0;Erythrocytes: 22.0;Foveolar cells: 20.2;Hepatocytes: 38.9;Neuroendocrine cells: 19.9;Pancreatic islet cells: 16.2;Parietal cells: 38.9" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 6 "Liver Hepatocellular Carcinoma (TCGA): 30.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA057689 Uncertain Uncertain Midbody,Centrosome Yes No "Cluster 13: Non-specific - Mitochondria" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 37: Neurons - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 92 Centrosome Midbody "HPA057689: " "unprognostic (8.97e-2)" "unprognostic (2.21e-1)" "unprognostic (1.19e-2)" "unprognostic (1.03e-1)" "unprognostic (7.83e-2)" "unprognostic (4.81e-2)" "unprognostic (4.02e-1)" "unprognostic (3.04e-1)" "unprognostic (1.60e-1)" "unprognostic (6.18e-2)" "potential prognostic unfavorable (2.00e-6)" "unprognostic (8.30e-2)" "unprognostic (1.03e-1)" "unprognostic (1.77e-3)" "unprognostic (8.16e-2)" "unprognostic (3.83e-3)" "unprognostic (1.38e-1)" "unprognostic (8.19e-2)" "unprognostic (9.71e-3)" "potential prognostic favorable (2.98e-4)" "unprognostic (1.11e-2)" "unprognostic (2.87e-1)" "unprognostic (9.14e-2)" "unprognostic (4.44e-3)" "unprognostic (2.63e-1)" "unprognostic (3.89e-2)" "unprognostic (7.95e-2)" "unprognostic (7.54e-2)" TMEM87A DKFZP564G2022 ENSG00000103978 "Transmembrane protein 87A" Q8NBN3 15 42210447-42273534 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018104, HPA018189" Enhanced Supported "Golgi apparatus" "Intracellular and membrane" "No annotated function" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 55: Breast - Lactation" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 81: Alveolar cells - Lung function" 73 "Golgi apparatus" "HPA018104: , HPA018189: " "unprognostic (3.92e-2)" "unprognostic (2.52e-2)" "unprognostic (4.42e-1)" "unprognostic (1.31e-2)" "unprognostic (1.55e-1)" "unprognostic (8.30e-2)" "unprognostic (2.67e-1)" "unprognostic (9.25e-2)" "unprognostic (2.63e-2)" "unprognostic (6.54e-2)" "potential prognostic favorable (1.54e-4)" "unprognostic (8.65e-3)" "unprognostic (2.92e-1)" "unprognostic (3.62e-2)" "unprognostic (1.74e-2)" "unprognostic (1.59e-1)" "unprognostic (2.66e-1)" "unprognostic (4.75e-2)" "unprognostic (6.07e-3)" "unprognostic (2.94e-3)" "unprognostic (2.39e-1)" "unprognostic (5.69e-3)" "unprognostic (1.17e-2)" "unprognostic (2.42e-1)" "unprognostic (2.13e-1)" "unprognostic (5.09e-2)" "unprognostic (2.43e-1)" "unprognostic (5.29e-2)" "unprognostic (1.58e-1)" "unprognostic (4.90e-2)" "unprognostic (2.05e-1)" TMEM87B FLJ14681 ENSG00000153214 "Transmembrane protein 87B" Q96K49 2 112055269-112119318 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cell type enhanced" "Detected in all" "endothelial cell: 186.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035183 Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 17: Intestine - Digestion" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 1 "Golgi apparatus, Vesicles" "HPA035183: " "unprognostic (4.67e-2)" "unprognostic (2.00e-1)" "unprognostic (2.18e-1)" "unprognostic (1.23e-3)" "unprognostic (1.64e-1)" "unprognostic (1.89e-2)" "unprognostic (6.72e-2)" "unprognostic (3.83e-1)" "unprognostic (8.81e-3)" "unprognostic (5.17e-2)" "unprognostic (1.20e-1)" "unprognostic (2.68e-1)" "unprognostic (3.56e-3)" "unprognostic (1.64e-3)" "unprognostic (1.29e-1)" "unprognostic (1.61e-2)" "unprognostic (4.63e-2)" "unprognostic (2.15e-1)" "unprognostic (3.24e-2)" "unprognostic (5.12e-2)" "unprognostic (4.53e-2)" "unprognostic (3.60e-2)" "unprognostic (2.87e-1)" "unprognostic (3.11e-1)" "unprognostic (8.42e-2)" "unprognostic (1.20e-1)" "unprognostic (6.11e-2)" "unprognostic (4.29e-1)" "unprognostic (8.00e-2)" "unprognostic (2.19e-1)" "unprognostic (4.87e-2)" TMEM88 "FLJ20025, MGC71744" ENSG00000167874 "Transmembrane protein 88" Q6PEY1 17 7855066-7856099 "Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 97.8" "Cell type enriched" "Detected in many" 6 "Vascular endothelial cells: 143.3" "Cell type enriched" "Detected in many" 9 "endothelial cell: 70.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.3" "Lineage enriched" "Detected in single" 14 "granulocytes: 1.3" "Cancer enriched" "Detected in many" 4 "Rhabdoid: 60.0" "Adrenal gland - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Prostate - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA052991 Approved NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 12: Non-specific - Vasculature" "Cluster 5: Rhabdoid - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 10 "HPA052991: " "unprognostic (7.29e-3)" "unprognostic (4.62e-1)" "unprognostic (5.12e-2)" "unprognostic (9.46e-2)" "unprognostic (7.04e-2)" "unprognostic (2.55e-1)" "unprognostic (2.76e-1)" "unprognostic (1.76e-1)" "unprognostic (6.67e-2)" "unprognostic (9.85e-3)" "validated prognostic favorable (1.26e-7)" "validated prognostic favorable (6.96e-5)" "unprognostic (1.01e-1)" "validated prognostic favorable (1.42e-5)" "validated prognostic favorable (9.76e-5)" "unprognostic (3.10e-2)" "unprognostic (1.57e-2)" "unprognostic (2.17e-2)" "unprognostic (7.10e-2)" "unprognostic (7.14e-2)" "unprognostic (1.25e-3)" "unprognostic (1.36e-3)" "unprognostic (5.31e-2)" "unprognostic (5.09e-2)" "unprognostic (5.29e-3)" "unprognostic (2.65e-1)" "unprognostic (1.38e-1)" "unprognostic (2.08e-3)" "unprognostic (3.86e-1)" "unprognostic (1.10e-1)" "unprognostic (2.97e-2)" TMEM88B ENSG00000205116 "Transmembrane protein 88B" A6NKF7 1 1425871-1430255 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 47 "brain: 191.5" "Cell type enhanced" "Detected in some" "Fibro-adipogenic progenitors: 1.1;Myosatellite cells: 1.3;Oligodendrocytes: 2.7;Schwann cells: 1.6;Sertoli cells: 2.8;Thymocytes: 1.7" "Cell type enriched" "Detected in single" 8 "oligodendrocyte: 3.8" "Cancer enhanced" "Detected in some" "Ovary Serous Cystadenocarcinoma (TCGA): 4.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 3.5" "Kidney - Podocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065743 Enhanced NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 5: Rhabdoid - Unknown function" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" "HPA065743: " "unprognostic (1.07e-1)" "unprognostic (3.61e-1)" "unprognostic (7.21e-2)" TMEM89 ENSG00000183396 "Transmembrane protein 89" A2RUT3 3 48620759-48621769 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "testis: 28.3" "Group enriched" "Detected in some" 167 "Early spermatids: 306.3;Late primary spermatocytes: 268.8;Late spermatids: 312.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA053577 Uncertain Approved "Perinuclear theca" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 15: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 1 "Perinuclear theca" "HPA053577: " "unprognostic (1.38e-1)" "unprognostic (7.78e-3)" TMEM8B "C9orf127, FP588, LINC00950, NAG-5, NGX6, NGX6a" ENSG00000137103 "Transmembrane protein 8B" A6NDV4 9 35814451-35865518 "Predicted membrane proteins, Transporters" "Cell adhesion, Growth regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 79.4;pDCs: 56.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "plasmacytoid DC: 51.3" "Lineage enriched" "Detected in many" 24 "dendritic cells: 51.3" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052130, HPA062701" Approved Approved Vesicles NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" Vesicles "HPA052130: , HPA062701: " "unprognostic (3.34e-3)" "unprognostic (4.12e-2)" "unprognostic (1.74e-1)" "unprognostic (8.53e-2)" "unprognostic (2.29e-1)" "unprognostic (3.22e-1)" "unprognostic (3.54e-1)" "unprognostic (9.72e-2)" "unprognostic (5.84e-2)" "unprognostic (2.67e-1)" "potential prognostic favorable (2.13e-7)" "unprognostic (1.08e-2)" "potential prognostic favorable (8.81e-5)" "unprognostic (3.58e-2)" "unprognostic (6.57e-2)" "unprognostic (8.00e-3)" "unprognostic (4.23e-1)" "unprognostic (8.02e-2)" "unprognostic (8.75e-2)" "unprognostic (2.25e-1)" "unprognostic (1.04e-2)" "potential prognostic favorable (3.37e-4)" "unprognostic (2.62e-2)" "unprognostic (1.12e-1)" "unprognostic (4.43e-2)" "unprognostic (2.90e-1)" "unprognostic (2.68e-1)" "unprognostic (1.77e-1)" "unprognostic (7.76e-2)" "unprognostic (1.26e-2)" "unprognostic (3.22e-2)" TMEM9 TMEM9A ENSG00000116857 "Transmembrane protein 9" Q9P0T7 1 201134772-201171574 "Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 212.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Breast glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008483 Approved "Vesicles,Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 65: Brain - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 45: Non-specific - Nuclear processes" "Cluster 94: Gonadal somatic cells - Mixed function" 107 Vesicles "Microtubules, Cytokinetic bridge, Mitotic spindle" "HPA008483: " "unprognostic (1.19e-1)" "unprognostic (3.21e-2)" "unprognostic (3.26e-2)" "unprognostic (1.29e-3)" "unprognostic (3.54e-1)" "unprognostic (1.41e-1)" "unprognostic (1.54e-1)" "unprognostic (3.30e-1)" "potential prognostic unfavorable (5.28e-4)" "potential prognostic unfavorable (1.09e-5)" "unprognostic (1.41e-2)" "unprognostic (8.71e-2)" "unprognostic (3.79e-2)" "unprognostic (1.89e-3)" "unprognostic (1.72e-2)" "unprognostic (3.49e-1)" "unprognostic (2.68e-1)" "unprognostic (6.17e-2)" "unprognostic (1.97e-1)" "unprognostic (1.28e-1)" "unprognostic (5.50e-2)" "unprognostic (8.71e-2)" "unprognostic (2.69e-1)" "unprognostic (1.30e-1)" "unprognostic (2.84e-2)" "unprognostic (1.78e-1)" "unprognostic (1.14e-2)" "unprognostic (7.32e-2)" "unprognostic (2.05e-1)" "unprognostic (8.85e-2)" "unprognostic (1.61e-2)" TMEM91 "DSPC3, FLJ27310, IFITMD6" ENSG00000142046 "Transmembrane protein 91" Q6ZNR0 19 41350911-41384083 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 99.1" "Group enriched" "Detected in many" 4 "Early spermatids: 207.4;Late spermatids: 720.6;Platelets: 549.2" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in all" 5 "Kidney Renal Clear Cell Carcinoma (TCGA): 131.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 194.5" "Group enriched" "Detected in all" 8 "granulocytes: 194.5;monocytes: 52.0" "Low cancer specificity" "Detected in all" "Skin - Sebaceous gland cells, Spleen - Neutrophils_2, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053240 Uncertain NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 2: Non-specific - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 1: Neuronal - Visual perception" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" "HPA053240: " "unprognostic (1.31e-1)" "unprognostic (1.12e-2)" "unprognostic (6.46e-2)" "unprognostic (1.07e-1)" "potential prognostic unfavorable (8.21e-4)" "unprognostic (4.70e-2)" "unprognostic (2.04e-2)" "unprognostic (5.68e-2)" "unprognostic (1.48e-1)" "unprognostic (6.32e-2)" "potential prognostic unfavorable (7.02e-4)" "unprognostic (1.92e-1)" "unprognostic (8.85e-2)" "unprognostic (2.34e-2)" "unprognostic (1.29e-2)" "unprognostic (6.62e-2)" "unprognostic (7.95e-3)" "unprognostic (2.76e-1)" "unprognostic (5.08e-2)" "unprognostic (2.76e-2)" "unprognostic (1.42e-1)" "unprognostic (1.76e-3)" "unprognostic (1.32e-2)" "unprognostic (1.54e-1)" "unprognostic (5.61e-2)" "unprognostic (1.32e-2)" "unprognostic (1.84e-1)" "unprognostic (5.97e-3)" "unprognostic (1.75e-1)" "unprognostic (4.04e-2)" "unprognostic (6.28e-2)" TMEM92 FLJ33318 ENSG00000167105 "Transmembrane protein 92" Q6UXU6 17 50271406-50281485 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 17.9;stomach 1: 10.4" "Cell type enhanced" "Detected in many" "Breast lactating cells: 115.7;Endometrial glandular cells: 28.2;Enterocytes: 295.0;Foveolar cells: 36.0;Gastric chief cells: 80.8;Mucous neck cells: 27.9;Paneth cells: 38.7;Parietal cells: 46.0" "Cell type enriched" "Detected in single" 12 "endothelial cell: 3.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 16.8" "Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA063009, HPA069820" Approved Uncertain Nucleoplasm NA NA "Cluster 77: Intestine - Digestion" "Cluster 47: Endothelial cells - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 1: Enterocytes - Absorption and Digestion" 2 Nucleoplasm "HPA063009: , HPA069820: " "unprognostic (1.95e-3)" "unprognostic (3.32e-1)" "unprognostic (4.87e-3)" "unprognostic (2.83e-1)" "unprognostic (2.38e-1)" "potential prognostic unfavorable (8.66e-5)" "unprognostic (1.14e-1)" "unprognostic (3.15e-1)" "unprognostic (2.09e-2)" "unprognostic (3.99e-3)" "unprognostic (6.22e-2)" "unprognostic (2.21e-2)" "unprognostic (2.00e-2)" "potential prognostic unfavorable (1.68e-4)" "unprognostic (5.83e-2)" "unprognostic (1.22e-1)" "unprognostic (7.65e-2)" "unprognostic (1.95e-3)" "unprognostic (3.94e-2)" "unprognostic (1.53e-1)" "unprognostic (9.21e-3)" "unprognostic (8.76e-2)" "unprognostic (4.96e-1)" "unprognostic (1.78e-1)" "unprognostic (3.09e-2)" TMEM94 KIAA0195 ENSG00000177728 "Transmembrane protein 94" Q12767 17 75441159-75500452 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 103.5;Retinal bipolar cells: 107.0;Rod photoreceptor cells: 97.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008423, HPA050660" Approved Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 27: Breast cancer - Unknown function" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 1 Nucleoplasm "Nuclear bodies" "HPA008423: , HPA050660: " "unprognostic (2.91e-1)" "unprognostic (7.58e-2)" "unprognostic (2.54e-2)" "unprognostic (9.39e-3)" "unprognostic (1.18e-1)" "unprognostic (2.06e-1)" "unprognostic (2.27e-1)" "unprognostic (6.30e-2)" "unprognostic (3.49e-2)" "validated prognostic favorable (1.06e-5)" "validated prognostic favorable (5.99e-4)" "unprognostic (4.15e-1)" "unprognostic (1.10e-2)" "unprognostic (4.04e-1)" "unprognostic (1.39e-2)" "unprognostic (1.20e-1)" "unprognostic (1.92e-3)" "unprognostic (4.74e-2)" "unprognostic (2.09e-2)" "unprognostic (1.32e-3)" "unprognostic (2.05e-2)" "unprognostic (1.41e-1)" "unprognostic (2.41e-2)" "unprognostic (3.56e-2)" "unprognostic (1.37e-1)" "unprognostic (2.90e-2)" "unprognostic (2.49e-1)" "unprognostic (5.76e-2)" "unprognostic (2.97e-1)" TMEM95 "MGC129793, UNQ9390" ENSG00000182896 "Transmembrane protein 95" Q3KNT9 17 7355123-7357219 "Predicted intracellular proteins, Predicted membrane proteins" Fertilization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 101 "testis: 10.0" "Group enriched" "Detected in some" 21 "Early spermatids: 3.6;Late primary spermatocytes: 4.0;Late spermatids: 4.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Intracellular and membrane" Other NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 25: Non-specific - Transcription" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 3 TMEM97 "σ2R, MAC30" ENSG00000109084 "Transmembrane protein 97" Q5BJF2 17 28319200-28328685 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 105.9;pancreas: 303.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 128.2;Cholangiocytes: 132.5;Gastric chief cells: 280.7;Gastric progenitor cells: 153.8;Granulosa cells: 127.3;Hepatocytes: 113.1;Mucous neck cells: 170.9;Oocytes: 331.6;Pancreatic acinar cells: 171.9;Parietal cells: 146.7;Urothelial cells: 230.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Sebaceous gland cells, Stomach - Chief cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044795, HPA076689" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 8: Pancreas - Proteolysis" "Cluster 24: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 69: Urothelial cells - Basic cellular functions" 50 "Endoplasmic reticulum" "HPA044795: , HPA076689: " "unprognostic (3.81e-2)" "unprognostic (5.48e-3)" "unprognostic (3.45e-1)" "unprognostic (1.64e-1)" "unprognostic (2.24e-1)" "unprognostic (3.97e-2)" "unprognostic (1.69e-1)" "unprognostic (1.33e-1)" "unprognostic (1.16e-1)" "potential prognostic unfavorable (3.69e-4)" "potential prognostic favorable (6.10e-4)" "unprognostic (1.32e-1)" "potential prognostic unfavorable (3.20e-4)" "unprognostic (1.77e-2)" "potential prognostic unfavorable (3.22e-5)" "unprognostic (3.09e-2)" "unprognostic (7.10e-2)" "unprognostic (1.10e-1)" "unprognostic (5.08e-3)" "unprognostic (8.40e-2)" "unprognostic (9.42e-2)" "unprognostic (2.62e-3)" "unprognostic (4.54e-3)" "unprognostic (2.63e-3)" "unprognostic (3.71e-2)" "unprognostic (2.31e-2)" "unprognostic (1.49e-2)" "unprognostic (3.93e-2)" "unprognostic (2.05e-1)" "unprognostic (4.25e-2)" "unprognostic (2.23e-1)" TMEM98 DKFZP564K1964 ENSG00000006042 "Transmembrane protein 98" Q9Y2Y6 17 32927910-32945106 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 392.6" "Cell type enriched" "Detected in many" 5 "Retinal pigment epithelial cells: 1206.4" "Group enriched" "Detected in many" 4 "choroid plexus epithelial cell: 140.4;committed oligodendrocyte precursor: 84.8;oligodendrocyte: 256.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 12 "plasmacytoid DC: 4.0" "Lineage enriched" "Detected in single" 12 "dendritic cells: 4.0" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Mesothelial cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040473, HPA053385" Uncertain Supported Nucleoplasm "Intracellular and membrane" "No annotated function" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 11: White matter - Signal transduction" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" 7 Nucleoplasm "HPA040473: , HPA053385: " "unprognostic (8.72e-3)" "unprognostic (1.54e-1)" "unprognostic (2.04e-1)" "potential prognostic unfavorable (2.76e-5)" "unprognostic (6.46e-2)" "unprognostic (4.93e-2)" "unprognostic (1.79e-1)" "unprognostic (3.74e-2)" "unprognostic (5.66e-2)" "unprognostic (4.99e-3)" "potential prognostic favorable (3.88e-4)" "unprognostic (4.70e-3)" "potential prognostic favorable (4.27e-4)" "unprognostic (3.68e-3)" "unprognostic (4.58e-2)" "unprognostic (6.84e-3)" "unprognostic (1.42e-1)" "unprognostic (8.73e-2)" "unprognostic (2.22e-2)" "unprognostic (2.49e-1)" "unprognostic (1.49e-1)" "unprognostic (2.52e-1)" "unprognostic (3.17e-3)" "unprognostic (4.63e-2)" "potential prognostic favorable (3.88e-4)" "unprognostic (4.16e-2)" "unprognostic (2.30e-3)" "unprognostic (4.20e-2)" "unprognostic (1.56e-1)" "unprognostic (1.49e-2)" "unprognostic (2.15e-2)" TMEM9B C11orf15 ENSG00000175348 "TMEM9 domain family member B" Q9NQ34 11 8947202-8965011 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 386.9;Esophageal suprabasal cells: 235.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037784 Approved NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 39: Astrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 85: Squamous epithelial cells - Keratinization" 65 "HPA037784: " "unprognostic (2.31e-1)" "unprognostic (1.44e-1)" "unprognostic (5.52e-2)" "unprognostic (1.15e-1)" "unprognostic (2.98e-2)" "unprognostic (1.66e-1)" "unprognostic (2.43e-1)" "unprognostic (5.64e-3)" "unprognostic (1.60e-2)" "unprognostic (6.74e-2)" "potential prognostic favorable (3.05e-5)" "unprognostic (5.32e-2)" "unprognostic (1.27e-3)" "unprognostic (4.59e-3)" "unprognostic (4.54e-2)" "unprognostic (1.03e-1)" "unprognostic (1.12e-1)" "unprognostic (5.50e-2)" "unprognostic (4.45e-2)" "unprognostic (6.86e-2)" "potential prognostic unfavorable (2.32e-4)" "unprognostic (1.55e-2)" "unprognostic (2.44e-1)" "unprognostic (2.57e-1)" "unprognostic (2.06e-1)" "unprognostic (1.78e-3)" "unprognostic (4.98e-2)" "unprognostic (1.50e-2)" "unprognostic (1.38e-1)" "unprognostic (2.72e-2)" "unprognostic (2.39e-1)" TMF1 "ARA160, TMF" ENSG00000144747 "TATA element modulatory factor 1" P82094 3 69019827-69052339 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 522.7;Late spermatids: 891.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008729 Approved Supported "Golgi apparatus" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 22: Epididymis - Mixed function" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 5 "Golgi apparatus" "HPA008729: " "unprognostic (1.13e-3)" "unprognostic (1.90e-1)" "unprognostic (2.98e-1)" "unprognostic (8.25e-3)" "unprognostic (8.79e-2)" "unprognostic (1.52e-2)" "unprognostic (2.03e-1)" "unprognostic (5.73e-2)" "unprognostic (2.30e-2)" "unprognostic (4.78e-3)" "potential prognostic favorable (4.82e-5)" "unprognostic (1.02e-2)" "unprognostic (2.68e-1)" "unprognostic (2.05e-3)" "unprognostic (2.78e-1)" "unprognostic (2.65e-2)" "unprognostic (1.82e-3)" "unprognostic (2.64e-1)" "unprognostic (1.08e-1)" "unprognostic (4.20e-2)" "unprognostic (2.99e-3)" "unprognostic (7.79e-3)" "unprognostic (4.78e-2)" "unprognostic (1.94e-2)" "unprognostic (3.62e-2)" "unprognostic (3.38e-1)" "unprognostic (8.07e-2)" "unprognostic (3.09e-3)" "unprognostic (1.12e-1)" "unprognostic (3.07e-2)" "unprognostic (2.39e-1)" TMIE DFNB6 ENSG00000181585 "Transmembrane inner ear" Q8NEW7 3 46694528-46710886 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 14.0;pituitary gland: 10.1" "Cell type enhanced" "Detected in some" "Corticotrophs: 6.7;Early primary spermatocytes: 4.5;Esophageal apical cells: 6.9;Gonadotrophs: 6.6;Other brain neurons: 6.7;Podocytes: 5.4;Retinal amacrine cells: 5.2;Retinal bipolar cells: 4.2;Retinal horizontal cells: 4.0;Somatotrophs: 4.9" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Glioblastoma Multiforme (TCGA): 10.9;Kidney Chromophobe (TCGA): 9.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD4 T-cell: 2.4" "Lineage enriched" "Detected in single" 15 "T-cells: 2.4" "Low cancer specificity" "Detected in some" "Adrenal gland - Adrenal medulla cells, Breast - T-cells, Kidney - Podocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038298 Uncertain Uncertain Vesicles,Cytosol NA NA "Cluster 11: T-cells - Unknown function" "Cluster 36: Brain & Liver - Signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 35: RS4;11 - Unknown function" "Cluster 109: Neurons - Neuronal signaling" "Vesicles, Cytosol" "HPA038298: " "unprognostic (3.34e-3)" "unprognostic (1.44e-2)" "unprognostic (2.71e-2)" "unprognostic (6.87e-3)" "unprognostic (1.03e-1)" "unprognostic (7.87e-2)" "unprognostic (6.15e-2)" "unprognostic (1.86e-2)" "unprognostic (3.12e-1)" "unprognostic (2.55e-1)" "unprognostic (1.86e-1)" "unprognostic (1.39e-1)" "unprognostic (1.79e-3)" TMIGD1 "TMIGD, UNQ9372" ENSG00000182271 "Transmembrane and immunoglobulin domain containing 1" Q6UXZ0 17 30316333-30334059 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 29 "intestine: 132.3" "Group enriched" "Detected in some" 26 "Colonocytes: 305.1;Enterocytes: 804.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Colon Adenocarcinoma (TCGA): 2.0;Rectum Adenocarcinoma (TCGA): 3.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "Gastric cancer: 1.1" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA021946 Uncertain Mitochondria,Cytosol NA NA "Cluster 77: Intestine - Digestion" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 1 "Mitochondria, Cytosol" "HPA021946: " "unprognostic (5.76e-2)" "unprognostic (1.75e-1)" "unprognostic (4.40e-1)" "unprognostic (8.39e-2)" TMIGD2 "CD28H, IGPR-1, MGC23244" ENSG00000167664 "Transmembrane and immunoglobulin domain containing 2" Q96BF3 19 4292227-4302431 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 32.5" "Group enriched" "Detected in some" 4 "Innate lymphoid cells: 139.5;NK-cells: 147.0;pDCs: 71.6" "Group enriched" "Detected in some" 32 "central nervous system macrophage: 19.0;leukocyte: 13.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 113.6" "Group enriched" "Detected in many" 38 "dendritic cells: 108.6;NK-cells: 89.3;T-cells: 113.6" "Group enriched" "Detected in some" 8 "Leukemia: 11.7;Neuroblastoma: 3.9" "Adipose visceral - T-cells, Liver - NK-cells (Liver), Skin - Sebaceous gland cells, Spleen - NK-cells (Spleen), Stomach - T-cells" "Low region specificity" "Detected in some" HPA011081 Approved NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 80: Thymus - Adaptive immune response" "Cluster 19: Astrocytes - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 1 "HPA011081: " "unprognostic (3.46e-3)" "unprognostic (4.46e-2)" "unprognostic (5.43e-2)" "unprognostic (3.89e-2)" "unprognostic (8.78e-2)" "unprognostic (1.18e-3)" "unprognostic (6.88e-2)" "unprognostic (9.88e-2)" "unprognostic (1.10e-1)" "unprognostic (4.97e-3)" "unprognostic (1.22e-1)" "unprognostic (2.30e-1)" "unprognostic (6.61e-2)" TMIGD3 AD026 ENSG00000121933 "Transmembrane and immunoglobulin domain containing 3" P0DMS9 1 111483348-111563962 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "testis: 51.5" "Group enriched" "Detected in some" 4 "Early spermatids: 248.7;Hofbauer cells: 524.7;Kupffer cells: 364.9;Late primary spermatocytes: 478.0;Late spermatids: 142.6;Microglia: 152.9" "Cell type enriched" "Detected in some" 50 "central nervous system macrophage: 181.1" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 4.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 44 "eosinophil: 63.0" "Lineage enriched" "Detected in many" 44 "granulocytes: 63.0" "Cancer enhanced" "Detected in single" "lymphoma: 2.4" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Lung - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Testis - Early spermatids, Thyroid gland - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 57: Testis - Spermatogenesis" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 50: Lymphoma - Unknown function" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" "unprognostic (1.09e-1)" "unprognostic (1.47e-1)" "unprognostic (2.04e-2)" "unprognostic (2.59e-1)" "unprognostic (1.94e-2)" "potential prognostic unfavorable (1.99e-4)" "unprognostic (1.71e-2)" "unprognostic (1.99e-1)" "potential prognostic favorable (4.44e-4)" TMLHE "BBOX2, FLJ10727, TMLH, XAP130" ENSG00000185973 "Trimethyllysine hydroxylase, epsilon" Q9NVH6 X 155489011-155719098 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carnitine biosynthesis" "Dioxygenase, Oxidoreductase" "Autism, Autism spectrum disorder, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 218.0;Cardiomyocytes: 352.0;Myonuclei: 875.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "HPA034589, HPA040331" Approved Supported Mitochondria NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 25: Non-specific - Transcription" "Cluster 36: Non-specific - mRNA processing" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 29 Mitochondria "HPA034589: , HPA040331: " "unprognostic (1.38e-1)" "unprognostic (5.31e-2)" "unprognostic (2.24e-1)" "unprognostic (1.93e-1)" "unprognostic (1.06e-1)" "unprognostic (1.15e-1)" "unprognostic (3.43e-3)" "unprognostic (3.92e-2)" "unprognostic (2.93e-2)" "unprognostic (2.56e-2)" "potential prognostic favorable (3.39e-7)" "unprognostic (7.37e-3)" "unprognostic (2.63e-1)" "unprognostic (8.50e-2)" "unprognostic (1.18e-1)" "unprognostic (8.64e-2)" "unprognostic (2.31e-1)" "unprognostic (1.52e-1)" "unprognostic (3.53e-2)" "unprognostic (1.06e-1)" "unprognostic (9.68e-2)" "unprognostic (2.41e-3)" "unprognostic (4.78e-2)" "unprognostic (7.10e-2)" "unprognostic (3.87e-3)" "unprognostic (1.27e-1)" "unprognostic (1.05e-1)" "unprognostic (1.85e-1)" "unprognostic (1.14e-1)" "unprognostic (2.18e-1)" "unprognostic (4.55e-1)" TMOD1 "D9S57E, ETMOD, TMOD" ENSG00000136842 "Tropomodulin 1" P28289 9 97501180-97601743 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 234.3;tongue: 238.8" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 563.8;Cardiomyocytes: 175.1;Mast cells: 193.5;Myonuclei: 159.6;Oocytes: 170.4;Pancreatic islet cells: 406.3;Pituitary stem cells: 326.8;Retinal horizontal cells: 252.4;Thymic myoid cells: 170.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 69.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in many" 6 "Neuroblastoma: 93.3" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal cortex cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051202 Enhanced NA NA 64000 "Cluster 24: Non-specific - Transcription" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 31: Non-specific - Transcription" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 38 "HPA051202: " "unprognostic (8.77e-2)" "unprognostic (1.24e-1)" "unprognostic (4.19e-3)" "unprognostic (5.45e-2)" "unprognostic (5.33e-2)" "unprognostic (9.38e-3)" "unprognostic (1.50e-1)" "unprognostic (6.69e-2)" "unprognostic (2.41e-3)" "unprognostic (6.07e-2)" "unprognostic (1.78e-2)" "unprognostic (8.48e-3)" "potential prognostic unfavorable (5.96e-5)" "unprognostic (2.46e-1)" "unprognostic (5.74e-3)" "unprognostic (1.03e-1)" "unprognostic (6.92e-2)" "unprognostic (2.14e-2)" "unprognostic (1.53e-2)" "unprognostic (7.97e-2)" "unprognostic (3.55e-1)" "unprognostic (1.60e-2)" "unprognostic (1.14e-1)" "unprognostic (1.37e-1)" "potential prognostic unfavorable (2.77e-5)" "unprognostic (3.58e-2)" "unprognostic (1.18e-1)" "unprognostic (6.42e-3)" "unprognostic (4.84e-2)" "unprognostic (2.89e-1)" "unprognostic (2.78e-2)" TMOD2 NTMOD ENSG00000128872 "Tropomodulin 2" Q9NZR1 15 51751597-51816363 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 63.1" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 95.7;Astrocytes: 105.7;Bergmann glia: 170.6;Brain excitatory neurons: 134.5;Brain inhibitory neurons: 118.6;Fibro-adipogenic progenitors: 98.8;Oligodendrocyte progenitor cells: 118.7;Oligodendrocytes: 99.0;Other brain neurons: 109.8;Retinal horizontal cells: 100.2;Schwann cells: 270.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 15.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 13.1" "Group enriched" "Detected in all" 4 "granulocytes: 13.1;monocytes: 10.7" "Cancer enhanced" "Detected in many" "Neuroblastoma: 18.0" "Colon - Enteric glia cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041365 Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 73: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 61: Schwann cells & Melanocytes - Mixed function" 9 "Nucleoli fibrillar center" Nucleoplasm "HPA041365: " "unprognostic (6.37e-2)" "unprognostic (3.64e-2)" "unprognostic (1.63e-1)" "unprognostic (1.71e-1)" "unprognostic (7.43e-2)" "unprognostic (2.08e-3)" "unprognostic (3.87e-2)" "unprognostic (2.21e-2)" "unprognostic (9.35e-2)" "unprognostic (2.54e-1)" "potential prognostic favorable (7.53e-5)" "unprognostic (1.07e-3)" "unprognostic (1.15e-1)" "unprognostic (9.43e-2)" "unprognostic (1.98e-3)" "unprognostic (3.28e-2)" "unprognostic (5.62e-3)" "unprognostic (1.68e-1)" "potential prognostic unfavorable (8.34e-4)" "potential prognostic favorable (2.69e-4)" "unprognostic (3.29e-2)" "unprognostic (2.48e-1)" "unprognostic (5.89e-2)" "unprognostic (1.12e-1)" "unprognostic (1.96e-1)" "unprognostic (1.83e-2)" "unprognostic (1.44e-1)" "unprognostic (6.86e-2)" TMOD3 UTMOD ENSG00000138594 "Tropomodulin 3" Q9NYL9 15 51829628-51947295 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 723.6;Esophageal apical cells: 1942.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Colon - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001849 Approved Approved "Actin filaments,Cytosol" NA NA 1500000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 24 Cytosol "Actin filaments" "HPA001849: " "unprognostic (2.14e-1)" "unprognostic (1.82e-2)" "unprognostic (3.01e-1)" "potential prognostic unfavorable (2.69e-5)" "unprognostic (1.31e-1)" "unprognostic (2.85e-1)" "unprognostic (1.63e-1)" "unprognostic (4.49e-3)" "unprognostic (1.52e-1)" "unprognostic (1.80e-3)" "validated prognostic favorable (1.02e-6)" "validated prognostic favorable (1.41e-4)" "unprognostic (1.88e-1)" "unprognostic (2.16e-2)" "unprognostic (3.79e-2)" "unprognostic (1.99e-3)" "unprognostic (3.40e-2)" "unprognostic (1.50e-2)" "unprognostic (2.12e-1)" "unprognostic (5.24e-2)" "unprognostic (1.68e-1)" "potential prognostic unfavorable (3.11e-5)" "unprognostic (1.07e-3)" "unprognostic (4.82e-2)" "unprognostic (7.22e-2)" "unprognostic (3.12e-2)" "unprognostic (8.63e-2)" "unprognostic (2.71e-1)" "unprognostic (4.83e-1)" "unprognostic (9.58e-2)" "unprognostic (1.75e-1)" TMOD4 Sk-Tmod ENSG00000163157 "Tropomodulin 4" Q9NZQ9 1 151169986-151176284 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 67 "skeletal muscle: 1148.5;tongue: 498.5" "Cell type enriched" "Detected in some" 4 "Myonuclei: 137.4" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in some" "Head and Neck Squamous Cell Carcinoma (TCGA): 4.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA028203 Enhanced NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 45: Non-specific - Nuclear processes" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 5 "HPA028203: " "potential prognostic favorable (3.49e-4)" "unprognostic (1.41e-1)" "unprognostic (2.89e-1)" "unprognostic (6.21e-2)" "unprognostic (2.65e-1)" "unprognostic (8.49e-3)" "unprognostic (2.03e-1)" "unprognostic (2.49e-3)" TMPO "LAP2, LEMD4, TP" ENSG00000120802 Thymopoietin "P42166, P42167" 12 98515579-98550351 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" DNA-binding Cardiomyopathy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 130.2" "Cell type enhanced" "Detected in all" "Erythrocyte progenitors: 360.6;Megakaryocyte progenitors: 282.7;Monocyte progenitors: 510.5" "Cell type enhanced" "Detected in all" "endothelial cell: 116.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells, Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Testis - Spermatogonia" "HPA008150, CAB009847, HPA070805" Enhanced Enhanced "Nuclear membrane" NA Yes 180000 "Cluster 33: Non-specific - ATP binding" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 31: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 27: Non-specific - Cell proliferation" 105 "Nuclear membrane" "CAB009847: , HPA008150: , HPA070805: " "unprognostic (2.74e-1)" "unprognostic (1.37e-1)" "unprognostic (1.18e-1)" "unprognostic (2.34e-1)" "unprognostic (2.18e-2)" "unprognostic (3.43e-2)" "unprognostic (7.48e-2)" "unprognostic (2.53e-2)" "unprognostic (4.95e-3)" "potential prognostic unfavorable (4.12e-5)" "unprognostic (5.01e-3)" "unprognostic (6.12e-2)" "unprognostic (3.24e-3)" "unprognostic (5.70e-3)" "unprognostic (1.45e-3)" "potential prognostic unfavorable (2.29e-4)" "unprognostic (7.95e-3)" "unprognostic (2.36e-3)" "unprognostic (1.50e-2)" "unprognostic (6.30e-2)" "unprognostic (1.56e-2)" "unprognostic (1.25e-1)" "unprognostic (1.66e-1)" "unprognostic (5.84e-2)" "unprognostic (1.12e-2)" "unprognostic (6.97e-2)" "unprognostic (6.05e-3)" "unprognostic (4.59e-2)" "unprognostic (3.56e-1)" "unprognostic (3.81e-2)" "unprognostic (1.53e-1)" TMPPE FLJ45032 ENSG00000188167 "Transmembrane protein with metallophosphoesterase domain" Q6ZT21 3 33090421-33097146 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 2.4" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027019 Approved Approved Nucleoplasm,Mitochondria Yes No "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 40: Non-specific - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 68: Foveolar cells - Mucosal defense" 30 "Nucleoplasm, Mitochondria" "HPA027019: " "unprognostic (2.69e-1)" "unprognostic (3.97e-2)" "unprognostic (1.39e-1)" "unprognostic (3.90e-2)" "unprognostic (2.13e-1)" "unprognostic (8.80e-3)" "unprognostic (7.12e-3)" "unprognostic (4.75e-1)" "unprognostic (3.67e-2)" "unprognostic (1.86e-1)" "unprognostic (1.73e-1)" "unprognostic (2.92e-1)" "unprognostic (1.84e-1)" "unprognostic (2.17e-1)" "unprognostic (5.84e-2)" "unprognostic (1.87e-1)" "unprognostic (1.34e-1)" TMPRSS11A "ECRG1, HATL1, HESP" ENSG00000187054 "Transmembrane serine protease 11A" Q6ZMR5 4 67909395-67964140 "Enzymes, Predicted membrane proteins, Transporters" "Cell cycle" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "cervix: 33.6;esophagus: 80.9;lymphoid tissue: 26.7;vagina: 39.0" "Cell type enriched" "Detected in many" 5 "Esophageal apical cells: 1411.0" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in some" 7 "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 25.2;Head and Neck Squamous Cell Carcinoma (TCGA): 20.2;Lung Squamous Cell Carcinoma (TCGA): 13.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Prostate - Urothelial cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA078316 Enhanced NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 24: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 1 "HPA078316: " "unprognostic (2.95e-2)" "unprognostic (2.06e-2)" "unprognostic (2.10e-2)" "unprognostic (5.92e-2)" "unprognostic (1.10e-2)" "unprognostic (4.72e-3)" "unprognostic (1.12e-1)" TMPRSS11B HATL5 ENSG00000185873 "Transmembrane serine protease 11B" Q86T26 4 68226653-68245694 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 105.8;esophagus: 382.6;vagina: 113.7" "Cell type enriched" "Detected in some" 52 "Esophageal apical cells: 17628.5" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 4.3;Head and Neck Squamous Cell Carcinoma (TCGA): 4.1;Stomach Adenocarcinoma (TCGA): 2.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pituitary gland - Thyrotropes" "Low region specificity" "Detected in all" NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 30: White matter - Myelination" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 84: Apical squamous epithelium - Cornification" 78 "unprognostic (6.32e-2)" "unprognostic (2.82e-3)" "unprognostic (4.31e-2)" TMPRSS11D "ASP, HAT" ENSG00000153802 "Transmembrane serine protease 11D" O60235 4 67820876-67884002 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 67.8;esophagus: 71.2;lymphoid tissue: 32.3;vagina: 77.9" "Cell type enriched" "Detected in many" 6 "Esophageal apical cells: 3693.4" "Cell type enhanced" "Detected in all" "mammillary body: 33.0" "Group enriched" "Detected in some" 12 "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 46.8;Head and Neck Squamous Cell Carcinoma (TCGA): 45.1;Lung Squamous Cell Carcinoma (TCGA): 18.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Esophageal cancer: 2.1;head and neck cancer: 1.6;lymphoma: 2.4" "Prostate - Urothelial cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA077704 Enhanced "Intracellular and membrane" Enzyme NA NA 32000000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 1 "HPA077704: " "unprognostic (5.51e-2)" "unprognostic (1.46e-1)" "unprognostic (2.95e-2)" "unprognostic (1.11e-1)" "unprognostic (2.50e-1)" "unprognostic (9.29e-3)" "unprognostic (3.52e-1)" "unprognostic (4.58e-1)" TMPRSS11E "DESC1, TMPRSS11E2" ENSG00000087128 "Transmembrane serine protease 11E" Q9UL52 4 68447463-68497604 "Enzymes, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 115.7;esophagus: 210.0;vagina: 156.3" "Group enriched" "Detected in some" 7 "Esophageal apical cells: 676.3;Salivary ionocytes: 330.8" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 26.4;Head and Neck Squamous Cell Carcinoma (TCGA): 30.0;Kidney Chromophobe (TCGA): 26.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 8.2" "Minor Salivary Gland - Minor salivary gland basal cells, Skin - Outer root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043816, HPA051062" Uncertain Approved "Golgi apparatus" "Secreted in other tissues" Enzyme NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 2 "Golgi apparatus" "HPA043816: , HPA051062: " "unprognostic (1.01e-1)" "unprognostic (1.92e-2)" "unprognostic (7.90e-2)" "unprognostic (1.29e-1)" "unprognostic (1.97e-1)" "unprognostic (1.98e-2)" "potential prognostic unfavorable (4.65e-5)" "unprognostic (5.55e-3)" "unprognostic (1.64e-1)" "unprognostic (2.77e-1)" "potential prognostic unfavorable (2.00e-8)" "unprognostic (6.28e-2)" "unprognostic (9.24e-2)" "unprognostic (9.52e-2)" "unprognostic (2.96e-1)" TMPRSS11F "FLJ16046, HATL4" ENSG00000198092 "Transmembrane serine protease 11F" Q6ZWK6 4 68053198-68129869 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "cervix: 4.9;esophagus: 14.2;lymphoid tissue: 3.8;skin 1: 8.8;vagina: 4.7" "Cell type enriched" "Detected in some" 4 "Esophageal apical cells: 287.0" "Cell type enhanced" "Detected in many" "lower rhombic lip: 7.1;mammillary body: 9.2" "Group enriched" "Detected in some" 7 "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 2.1;Head and Neck Squamous Cell Carcinoma (TCGA): 2.9;Lung Squamous Cell Carcinoma (TCGA): 1.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 1.1;Leukemia: 1.0;lymphoma: 1.8" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA026911 Uncertain NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 49: Hindbrain - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" "HPA026911: " "unprognostic (1.46e-1)" "unprognostic (1.03e-1)" "unprognostic (5.48e-2)" "unprognostic (4.78e-2)" TMPRSS12 "CT151, MGC57341" ENSG00000186452 "Transmembrane serine protease 12" Q86WS5 12 50842920-50887884 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Fertilization, Spermatogenesis" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 50 "testis: 20.2" "Cell type enriched" "Detected in many" 7 "Late primary spermatocytes: 271.1" "Low cell type specificity" "Detected in some" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Ascending Loop of Henle cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 6 TMPRSS13 "MSPL, MSPS, TMPRSS11" ENSG00000137747 "Transmembrane serine protease 13" Q9BYE2 11 117900641-117929459 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 14.3;skin 1: 36.8" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 19.4;Cytotrophoblasts: 18.0;Esophageal apical cells: 97.6;Esophageal suprabasal cells: 39.4;Extravillous trophoblasts: 28.2;Lacrimal acinar cells: 25.4;Migrating cytotrophoblasts: 30.3;Respiratory ionocytes: 30.5;Salivary duct cells: 17.2;Salivary ionocytes: 44.5;Suprabasal keratinocytes: 18.3;Syncytiotrophoblasts: 25.4" "Cell type enhanced" "Detected in some" "deep-layer corticothalamic and 6b: 1.6;hippocampal CA1-3: 2.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 15.5" "Breast - Breast glandular cells, Pancreas - Ductal cells, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Not detected" "Not detected" HPA079555 Approved "Nucleoplasm,Plasma membrane" "Secreted in other tissues" Enzyme NA NA 130000000 "Cluster 13: Non-specific - Mitochondria" "Cluster 58: Skin - Keratinization" "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 1 "Nucleoplasm, Plasma membrane" "HPA079555: " "unprognostic (8.68e-2)" "unprognostic (1.03e-3)" "unprognostic (1.24e-1)" "unprognostic (2.06e-3)" "unprognostic (1.64e-1)" "unprognostic (6.50e-2)" "unprognostic (2.64e-1)" "unprognostic (6.84e-3)" "unprognostic (5.52e-2)" "unprognostic (3.01e-2)" "unprognostic (4.16e-2)" "unprognostic (1.49e-1)" "unprognostic (2.53e-2)" "unprognostic (1.90e-3)" "unprognostic (7.47e-3)" "unprognostic (2.60e-2)" "unprognostic (3.38e-1)" "unprognostic (3.09e-2)" "unprognostic (4.02e-2)" "unprognostic (1.95e-1)" "unprognostic (5.02e-2)" "unprognostic (7.86e-2)" "unprognostic (2.58e-1)" "unprognostic (3.26e-2)" TMPRSS15 "ENTK, MGC133046, PRSS7" ENSG00000154646 "Transmembrane serine protease 15" P98073 21 18269116-18485879 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 932 "intestine: 921.9" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 10.6;Early spermatids: 7.7;Enteric transient amplifying cells: 28.9;Enterocytes: 50.8;Foveolar cells: 5.2;Retinal ganglion cells: 7.7;Undifferentiated spermatogonia: 5.1" "Cell type enhanced" "Detected in some" "miscellaneous: 4.5;thalamic excitatory: 2.8" "Group enriched" "Detected in some" 7 "Liver Hepatocellular Carcinoma (TCGA): 1.0;Pancreatic Adenocarcinoma (TCGA): 2.9;Stomach Adenocarcinoma (TCGA): 2.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "Rhabdoid: 56.9" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "olfactory bulb: 7.2;spinal cord: 2.6" "HPA015611, HPA034857, HPA072934" Enhanced Approved "Plasma membrane" NA NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 15: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 1: Enterocytes - Absorption and Digestion" "Plasma membrane" "HPA015611: , HPA034857: , HPA072934: " "unprognostic (9.72e-2)" "potential prognostic unfavorable (1.49e-4)" "unprognostic (2.57e-1)" "unprognostic (2.43e-1)" "unprognostic (7.71e-3)" "unprognostic (2.42e-2)" "unprognostic (9.45e-3)" TMPRSS2 PRSS10 ENSG00000184012 "Transmembrane serine protease 2" O15393 21 41464300-41531116 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Host-virus interaction" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 263.4;stomach 1: 138.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 262.1;Colonocytes: 465.3;Distal convoluted tubule cells: 339.8;Enterocytes: 321.4;Esophageal apical cells: 423.6;Foveolar cells: 465.0;Mucous neck cells: 293.7;Parietal cells: 422.5;Prostatic club cells: 497.6;Prostatic glandular cells: 1305.2;Renal collecting duct intercalated cells: 537.1;Renal connecting tubule cells: 265.9;Urothelial cells: 452.0" "Cell type enriched" "Detected in single" 9 "choroid plexus epithelial cell: 6.5" "Cancer enriched" "Detected in many" 5 "Prostate Adenocarcinoma (TCGA): 644.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "prostate cancer: 267.6" "Colon - Colon enterocytes, Kidney - Intercalated cells, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA034493, HPA035787" Enhanced Supported "Plasma membrane" "Secreted in other tissues" Enzyme NA NA "Cluster 60: Stomach - Digestion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 71 "Plasma membrane" "HPA034493: , HPA035787: " "unprognostic (3.93e-3)" "unprognostic (2.10e-3)" "unprognostic (7.93e-2)" "unprognostic (1.09e-1)" "unprognostic (6.55e-2)" "unprognostic (1.88e-2)" "unprognostic (1.95e-2)" "unprognostic (8.31e-2)" "unprognostic (4.58e-1)" "unprognostic (7.00e-3)" "unprognostic (4.06e-2)" "potential prognostic favorable (9.91e-5)" "potential prognostic favorable (6.80e-4)" "unprognostic (2.58e-1)" "unprognostic (2.22e-1)" "unprognostic (1.10e-1)" "unprognostic (6.10e-2)" "unprognostic (2.12e-3)" "unprognostic (3.63e-2)" "unprognostic (2.67e-3)" "unprognostic (1.28e-1)" "unprognostic (1.14e-1)" "unprognostic (1.41e-2)" "unprognostic (4.11e-2)" "unprognostic (1.66e-1)" "unprognostic (2.22e-1)" "unprognostic (4.21e-2)" TMPRSS3 "DFNB10, DFNB8" ENSG00000160183 "Transmembrane serine protease 3" P57727 21 42371887-42396091 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 22.3;stomach 1: 13.7" "Cell type enhanced" "Detected in many" "Breast lactating cells: 37.3;Breast secretory cells: 34.1;Cholangiocytes: 25.9;Endometrial ciliated cells: 33.1;Endometrial secretory cells: 29.5;Fallopian secretory cells: 27.9;Fallopian tube ciliated cells: 89.4;Foveolar cells: 39.4;Mucous neck cells: 35.9;Müller glia: 26.5;Pancreatic duct cells: 28.8;Respiratory ciliated cells: 35.8;Salivary ionocytes: 36.9" "Group enriched" "Detected in some" 4 "astrocyte: 5.2;leukocyte: 3.4" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 47.0" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 3.2" "Lineage enriched" "Detected in single" 6 "T-cells: 3.2" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Liver - Cholangiocytes, Minor Salivary Gland - Minor salivary glandular cells, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 19: Astrocytes - Mixed function" "Cluster 20: Myeloma - Immune response" "Cluster 68: Foveolar cells - Mucosal defense" "unprognostic (1.88e-2)" "unprognostic (1.23e-2)" "unprognostic (6.45e-2)" "unprognostic (3.05e-1)" "unprognostic (4.85e-2)" "potential prognostic unfavorable (8.76e-4)" "potential prognostic unfavorable (2.15e-4)" "unprognostic (1.38e-1)" "unprognostic (2.08e-2)" "unprognostic (1.77e-1)" "unprognostic (1.38e-1)" "unprognostic (4.09e-2)" "unprognostic (5.19e-2)" "unprognostic (6.55e-2)" "unprognostic (2.37e-2)" "unprognostic (5.42e-2)" "unprognostic (6.24e-3)" "unprognostic (7.40e-2)" "unprognostic (1.72e-2)" "unprognostic (4.13e-1)" "unprognostic (1.38e-2)" "unprognostic (3.92e-3)" "unprognostic (1.33e-1)" "unprognostic (2.29e-1)" "unprognostic (8.00e-2)" "unprognostic (2.04e-2)" "unprognostic (1.01e-1)" TMPRSS4 "CAP2, MT-SP2, TMPRSS3" ENSG00000137648 "Transmembrane serine protease 4" Q9NRS4 11 118077012-118121890 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Host-virus interaction" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 81.7;intestine: 40.8;urinary bladder: 69.6" "Cell type enhanced" "Detected in many" "Colonocytes: 293.1;Conjunctival goblet cells: 363.1;Esophageal apical cells: 549.4;Esophageal basal cells: 272.7;Esophageal suprabasal cells: 414.1;Ocular epithelial cells: 542.5;Paneth cells: 228.2;Papillary tip epithelial cells: 333.6;Prostatic hillock cells: 800.2;Respiratory basal cells: 445.5;Respiratory deuterosomal cells: 266.4;Respiratory secretory cells: 390.8;Salivary duct cells: 442.9;Urothelial cells: 535.1" "Cell type enriched" "Detected in single" 6 "central nervous system macrophage: 6.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "basophil: 2.0" "Lineage enriched" "Detected in single" 9 "granulocytes: 2.0" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 70.1" "Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Urothelial cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA006238 Uncertain "Secreted in other tissues" Enzyme NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 69 "HPA006238: " "unprognostic (8.54e-3)" "unprognostic (1.19e-1)" "unprognostic (8.73e-2)" "potential prognostic favorable (7.26e-4)" "unprognostic (1.88e-1)" "unprognostic (2.92e-1)" "unprognostic (2.96e-2)" "unprognostic (9.21e-3)" "unprognostic (9.02e-2)" "unprognostic (2.69e-1)" "unprognostic (2.07e-3)" "unprognostic (1.36e-1)" "unprognostic (4.85e-3)" "unprognostic (6.52e-2)" "unprognostic (2.13e-1)" "unprognostic (4.11e-2)" "potential prognostic unfavorable (1.37e-4)" "unprognostic (1.49e-3)" "unprognostic (9.41e-2)" "unprognostic (4.79e-1)" "unprognostic (2.17e-1)" "unprognostic (1.14e-1)" "unprognostic (2.33e-1)" "unprognostic (2.84e-1)" "unprognostic (6.98e-3)" "unprognostic (2.77e-1)" TMPRSS5 "MGC141886, MGC148044" ENSG00000166682 "Transmembrane serine protease 5" Q9H3S3 11 113687547-113706373 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 17.4;salivary gland: 9.5" "Cell type enhanced" "Detected in many" "Adipocytes: 19.3;Astrocytes: 38.6;Ependymal cells: 38.5;Myonuclei: 23.4;Oligodendrocytes: 27.3;Salivary acinar cells: 47.7;Salivary myoepithelial cells: 29.4;Schwann cells: 40.8;Submucosal glandular cells: 13.6" "Group enriched" "Detected in all" 4 "astrocyte: 40.7;Bergmann glia: 12.1;committed oligodendrocyte precursor: 27.0;ependymal cell: 37.9;oligodendrocyte: 25.6" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 10.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 4.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010992 Approved Nucleoplasm NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 28 Nucleoplasm "HPA010992: " "unprognostic (6.81e-2)" "unprognostic (1.07e-1)" "unprognostic (3.21e-1)" "unprognostic (3.50e-1)" "unprognostic (6.67e-2)" "unprognostic (2.06e-1)" "unprognostic (2.85e-1)" "unprognostic (2.92e-1)" "unprognostic (2.42e-1)" "unprognostic (3.37e-2)" "unprognostic (1.82e-2)" "unprognostic (5.45e-2)" TMPRSS6 "FLJ30744, MT2" ENSG00000187045 "Transmembrane serine protease 6" Q8IU80 22 37065436-37109713 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "liver: 129.5" "Group enriched" "Detected in some" 5 "Early spermatids: 85.9;Hepatocytes: 116.4;Late spermatids: 246.6" "Cell type enhanced" "Detected in single" "medium spiny neuron: 2.0" "Group enriched" "Detected in many" 8 "Liver Hepatocellular Carcinoma (TCGA): 82.6;Thyroid Carcinoma (TCGA): 25.8" "Region enhanced" "Detected in many" "basal ganglia: 10.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 3.6;lymphoma: 2.9" "Breast - Breast glandular cells, Liver - Hepatocytes, Pancreas - Alpha cells, Pancreas - Beta cells, Spleen - T-cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 33: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" "unprognostic (1.13e-1)" "unprognostic (3.77e-2)" "unprognostic (2.34e-1)" "validated prognostic favorable (9.70e-6)" "validated prognostic favorable (7.23e-6)" "unprognostic (8.15e-2)" "unprognostic (8.09e-2)" "unprognostic (1.87e-1)" "unprognostic (3.10e-2)" "unprognostic (6.10e-3)" "unprognostic (9.56e-2)" "unprognostic (4.26e-2)" "unprognostic (2.94e-3)" TMPRSS7 ENSG00000176040 "Transmembrane serine protease 7" Q7RTY8 3 112034736-112081269 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "testis: 1.3" "Cell type enhanced" "Detected in some" "Corticotrophs: 7.6;Early spermatids: 6.2;Fallopian tube ciliated cells: 6.4;Goblet cells: 8.3;Lactotrophs: 5.8;Late primary spermatocytes: 18.3;Late spermatids: 5.8;Respiratory ciliated cells: 14.2;Urothelial cells: 5.9" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Minor Salivary Gland - Minor salivary glandular cells, Skin - Keratinocyte (granular), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" "Region enhanced" "Detected in single" "cerebral cortex: 1.4" HPA040630 Uncertain NA NA "Cluster 21: Testis - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 70: Intestinal goblet cells - Mucin production" "HPA040630: " "unprognostic (1.40e-2)" TMPRSS9 ENSG00000178297 "Transmembrane serine protease 9" Q7Z410 19 2360238-2426261 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "liver: 4.1;lymphoid tissue: 2.2;testis: 3.6" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 54.2;Cardiomyocytes: 30.4;Endometrial glandular cells: 30.9;Endometrial luminal cells: 30.8;Epicardial cells: 40.9;Granulosa cells: 33.3;Late primary spermatocytes: 31.6;Late spermatids: 116.0;Myonuclei: 35.5;Undifferentiated spermatogonia: 30.9" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Skin Cutaneous Melanoma (TCGA): 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA051483 Uncertain NA NA "Cluster 47: Testis - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 20: Non-specific - Transcription regulation" "HPA051483: " "unprognostic (1.22e-1)" "unprognostic (1.85e-1)" "unprognostic (5.28e-2)" "unprognostic (2.60e-1)" "unprognostic (8.17e-2)" "unprognostic (7.23e-3)" "unprognostic (2.69e-2)" TMSB10 TB10 ENSG00000034510 "Thymosin beta 10" P63313 2 84905656-84906671 "Essential proteins, Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 8296.1;Endometrial luminal cells: 8087.5;Enteric transient amplifying cells: 9113.1;Enterocytes: 8870.5;Epididymal principal cells: 9412.4;Esophageal apical cells: 13890.7;Esophageal suprabasal cells: 9192.2;Extravillous trophoblasts: 17493.9;Kupffer cells: 11215.6;Ovarian stromal cells: 8309.8" "Cell type enhanced" "Detected in all" "endothelial cell: 1130.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells" "Not detected" "Not detected" NA NA 36000000 "Cluster 29: Non-specific - Unknown function" "Cluster 49: Non-specific - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 15: Non-specific - Protein processing" 14 "unprognostic (4.69e-3)" "unprognostic (1.37e-1)" "unprognostic (4.19e-1)" "unprognostic (2.35e-1)" "unprognostic (5.50e-2)" "unprognostic (1.98e-1)" "unprognostic (1.50e-2)" "unprognostic (7.93e-2)" "unprognostic (5.53e-2)" "unprognostic (1.77e-1)" "unprognostic (5.25e-3)" "unprognostic (1.74e-3)" "unprognostic (2.13e-1)" "potential prognostic unfavorable (5.36e-4)" "unprognostic (2.08e-1)" "potential prognostic unfavorable (5.33e-6)" "unprognostic (1.62e-2)" "unprognostic (4.43e-2)" "unprognostic (1.40e-3)" "unprognostic (7.64e-2)" "unprognostic (1.76e-1)" "unprognostic (2.08e-3)" "potential prognostic unfavorable (3.89e-4)" "unprognostic (1.74e-1)" "unprognostic (1.30e-1)" "unprognostic (2.13e-1)" "unprognostic (5.32e-2)" "unprognostic (4.58e-2)" "unprognostic (2.22e-1)" "unprognostic (2.27e-3)" "unprognostic (7.42e-2)" TMSB15A "TMSL8, TMSNB" ENSG00000158164 "Thymosin beta 15A" P0CG34 X 102513682-102516739 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 12.0;ovary: 15.9;prostate: 14.8" "Cell type enhanced" "Detected in some" "Breast secretory cells: 9.8;Differentiating spermatogonia: 20.4;Granulosa cells: 24.3;Megakaryocyte progenitors: 21.7;Megakaryocytes: 74.2;Oocytes: 73.7;Ovarian stromal cells: 14.1;Platelets: 15.4;Undifferentiated spermatogonia: 17.7" "Cell type enhanced" "Detected in some" "midbrain-derived inhibitory: 2.7;pericyte: 2.2;vascular associated smooth muscle cell: 1.7" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 115.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 157.0" "Breast - T-cells, Prostate - Prostate glandular cells, Skin - Outer root sheath cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" NA NA 35000 "Cluster 15: NK-cells - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 94: Gonadal somatic cells - Mixed function" "unprognostic (5.07e-2)" "unprognostic (1.33e-3)" "unprognostic (2.97e-1)" "unprognostic (2.74e-2)" "unprognostic (1.80e-1)" "unprognostic (1.75e-1)" "unprognostic (3.42e-3)" "unprognostic (5.18e-2)" "potential prognostic unfavorable (3.02e-5)" "unprognostic (4.03e-3)" "unprognostic (1.66e-2)" "unprognostic (2.78e-1)" "unprognostic (7.73e-2)" "unprognostic (1.20e-1)" "unprognostic (1.93e-2)" "unprognostic (1.25e-2)" "unprognostic (6.01e-2)" "unprognostic (6.94e-2)" "unprognostic (1.54e-1)" "unprognostic (4.67e-2)" "unprognostic (7.50e-2)" "potential prognostic unfavorable (5.52e-5)" "unprognostic (2.87e-1)" "unprognostic (1.72e-1)" "unprognostic (7.95e-2)" TMSB15B MGC39900 ENSG00000158427 "Thymosin beta 15B" P0CG35 X 103918896-103966712 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Gastric progenitor cells: 3.8;Gonadotrophs: 8.7;Megakaryocyte progenitors: 4.0;Megakaryocyte-Erythroid progenitors: 4.1;Pancreatic islet cells: 11.0;Platelets: 7.0;Sertoli cells: 12.9;Thymocytes: 6.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" HPA064607 Uncertain NA NA "Cluster 24: Non-specific - Transcription" "Cluster 75: Ovary - Mixed function" "Cluster 2: Neurons - Nucleosome" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" "HPA064607: " "unprognostic (2.19e-1)" "unprognostic (6.02e-3)" "unprognostic (3.32e-1)" "unprognostic (3.65e-3)" "unprognostic (1.00e-1)" "unprognostic (2.99e-2)" "unprognostic (2.33e-1)" "unprognostic (1.49e-3)" "unprognostic (3.26e-1)" "unprognostic (1.48e-2)" "unprognostic (6.14e-2)" "unprognostic (4.25e-3)" "unprognostic (3.10e-1)" "unprognostic (7.04e-2)" "unprognostic (8.75e-2)" "unprognostic (1.23e-2)" "unprognostic (2.91e-1)" "unprognostic (2.43e-2)" "unprognostic (1.53e-1)" "unprognostic (3.00e-1)" "unprognostic (1.29e-1)" "unprognostic (7.67e-2)" "unprognostic (3.29e-1)" "unprognostic (2.23e-2)" "potential prognostic unfavorable (4.10e-4)" "unprognostic (4.92e-3)" "unprognostic (1.09e-1)" "unprognostic (8.88e-2)" "unprognostic (8.39e-2)" TMSB15B ENSG00000269226 "Thymosin beta 15B" X 104063871-104076236 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "ovary: 13.1" "Cell type enriched" "Detected in single" 5 "Medullary thymic epithelial cells: 2.4" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" NA NA "Cluster 18: Non-specific - Translation" "Cluster 75: Ovary - Mixed function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 58: Mast cells - Allergic inflammatory responses" "unprognostic (6.94e-2)" "unprognostic (2.11e-2)" "potential prognostic favorable (2.05e-4)" "unprognostic (4.83e-1)" "unprognostic (4.42e-3)" "unprognostic (1.24e-3)" "unprognostic (1.50e-1)" "unprognostic (6.70e-2)" "unprognostic (4.66e-2)" "unprognostic (3.91e-2)" "unprognostic (1.92e-1)" "unprognostic (1.88e-2)" "potential prognostic favorable (2.77e-5)" "unprognostic (2.24e-2)" "unprognostic (2.68e-2)" TMSB4X "TB4X, TMSB4" ENSG00000205542 "Thymosin beta 4 X-linked" P62328 X 12975110-12977227 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "cDC: 22882.3;Decidual stromal cells: 27197.9;Hofbauer cells: 36355.5;Kupffer cells: 30346.5;Megakaryocytes: 73790.0;Parietal cells: 13370.6;Platelets: 38486.1" "Cell type enhanced" "Detected in all" "leukocyte: 852.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells" "Low region specificity" "Detected in all" CAB033806 Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA 950000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 5: Spleen - Immune response" "Cluster 7: Non-specific - Ribosome" "Cluster 55: Lymphoma - Immune response" "Cluster 82: Dendritic cells - Antigen presentation" 17 "Nucleoplasm, Vesicles, Cytosol" "CAB033806: " "unprognostic (3.19e-2)" "unprognostic (2.47e-2)" "unprognostic (3.61e-3)" "unprognostic (8.85e-3)" "unprognostic (1.23e-1)" "unprognostic (3.24e-2)" "unprognostic (2.11e-2)" "unprognostic (1.35e-1)" "unprognostic (1.11e-1)" "unprognostic (6.20e-2)" "unprognostic (5.70e-2)" "unprognostic (2.20e-1)" "unprognostic (4.91e-3)" "unprognostic (2.39e-1)" "unprognostic (2.82e-2)" "unprognostic (6.68e-2)" "unprognostic (1.08e-1)" "unprognostic (1.01e-1)" "unprognostic (4.00e-2)" "unprognostic (1.25e-1)" "unprognostic (1.23e-3)" "unprognostic (5.89e-2)" "unprognostic (1.70e-1)" "unprognostic (8.84e-2)" "unprognostic (4.63e-2)" "unprognostic (8.20e-2)" "unprognostic (2.64e-2)" "unprognostic (1.41e-1)" "unprognostic (1.69e-2)" "unprognostic (2.35e-1)" TMSB4Y TB4Y ENSG00000154620 "Thymosin beta 4 Y-linked" O14604 Y 13703899-13706024 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 6.2" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 1.3;Podocytes: 1.5;Renal connecting tubule cells: 1.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 2 "unprognostic (1.26e-1)" "unprognostic (2.81e-2)" "unprognostic (4.48e-2)" "unprognostic (1.11e-1)" "unprognostic (3.89e-2)" "unprognostic (1.54e-1)" "unprognostic (1.99e-1)" "unprognostic (4.33e-1)" "unprognostic (2.87e-1)" "unprognostic (4.72e-2)" "unprognostic (7.81e-2)" "unprognostic (4.09e-1)" TMTC1 "ARG99, FLJ31400, FLJ41625, OLF" ENSG00000133687 "Transmembrane O-mannosyltransferase targeting cadherins 1" Q8IUR5 12 29500840-29784759 "Enzymes, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 337.7;Corticotrophs: 362.5;Fibro-adipogenic progenitors: 340.7;Gonadotrophs: 408.8;Lymphatic endothelial cells: 462.1;Medullary thymic epithelial cells: 360.0;Myonuclei: 512.3;Myosatellite cells: 428.3;Retinal amacrine cells: 390.3;Somatotrophs: 425.4;Vascular endothelial cells: 721.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016720 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 38: Sub-cortical - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" "Nucleoplasm, Cytosol" "HPA016720: " "unprognostic (3.87e-2)" "unprognostic (2.89e-1)" "unprognostic (6.78e-2)" "unprognostic (6.21e-2)" "unprognostic (1.06e-1)" "unprognostic (3.67e-2)" "unprognostic (4.21e-2)" "unprognostic (4.51e-2)" "unprognostic (8.41e-2)" "unprognostic (2.91e-1)" "potential prognostic favorable (1.85e-9)" "unprognostic (2.30e-3)" "unprognostic (1.12e-3)" "unprognostic (8.36e-2)" "unprognostic (2.26e-1)" "unprognostic (4.15e-1)" "unprognostic (1.03e-1)" "unprognostic (7.95e-3)" "unprognostic (1.20e-2)" "unprognostic (3.34e-2)" "unprognostic (1.98e-1)" "unprognostic (1.56e-2)" "unprognostic (3.36e-1)" "unprognostic (1.04e-1)" "unprognostic (1.61e-1)" "unprognostic (4.12e-2)" "unprognostic (1.54e-1)" "potential prognostic unfavorable (4.87e-4)" "unprognostic (2.06e-1)" "unprognostic (2.08e-1)" "unprognostic (1.30e-1)" TMTC2 DKFZp762A217 ENSG00000179104 "Transmembrane O-mannosyltransferase targeting cadherins 2" Q8N394 12 82686880-83134870 "Enzymes, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Corticotrophs: 840.2;Oligodendrocytes: 2383.5;Renal collecting duct principal cells: 856.0;Renal connecting tubule cells: 1201.9;Retinal bipolar cells: 779.1" "Cell type enhanced" "Detected in all" "oligodendrocyte: 3223.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 27.8" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026954, HPA026955" Uncertain Approved "Plasma membrane,Actin filaments" No No "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 80: Oligodendrocytes - Myelination" 5 "Plasma membrane" "Actin filaments" "HPA026954: , HPA026955: " "unprognostic (4.64e-2)" "unprognostic (1.42e-1)" "unprognostic (2.72e-1)" "unprognostic (1.37e-1)" "unprognostic (9.67e-2)" "unprognostic (4.52e-2)" "unprognostic (4.59e-2)" "unprognostic (4.15e-2)" "unprognostic (5.09e-2)" "unprognostic (5.97e-2)" "validated prognostic favorable (1.27e-9)" "validated prognostic favorable (2.41e-4)" "unprognostic (5.38e-3)" "unprognostic (3.03e-1)" "unprognostic (1.99e-1)" "unprognostic (3.41e-1)" "unprognostic (6.20e-2)" "unprognostic (6.59e-2)" "unprognostic (2.62e-2)" "unprognostic (1.75e-3)" "unprognostic (3.07e-3)" "unprognostic (5.19e-2)" "unprognostic (1.18e-1)" "unprognostic (2.73e-2)" "unprognostic (1.19e-1)" "unprognostic (1.59e-1)" "unprognostic (7.68e-2)" "unprognostic (4.68e-2)" "unprognostic (7.19e-3)" "unprognostic (8.49e-3)" TMTC3 "FLJ90492, SMILE" ENSG00000139324 "Transmembrane O-mannosyltransferase targeting cadherins 3" Q6ZXV5 12 88142296-88199887 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Transferase "Disease variant, Lissencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ocular epithelial cells: 121.8;Respiratory ionocytes: 170.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038550 Approved NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 7: Liver cancer - Metabolism" "Cluster 100: Stratified epithelial cells - Barrier functions" 4 "HPA038550: " "unprognostic (8.05e-2)" "unprognostic (1.71e-2)" "unprognostic (1.40e-1)" "unprognostic (3.06e-1)" "unprognostic (8.23e-2)" "unprognostic (1.45e-1)" "unprognostic (3.11e-1)" "potential prognostic unfavorable (7.04e-5)" "unprognostic (8.20e-2)" "unprognostic (5.34e-2)" "potential prognostic favorable (9.01e-6)" "unprognostic (1.53e-2)" "unprognostic (7.07e-3)" "unprognostic (1.15e-3)" "unprognostic (6.17e-2)" "potential prognostic unfavorable (1.91e-4)" "unprognostic (2.55e-2)" "unprognostic (6.16e-3)" "unprognostic (1.25e-1)" "unprognostic (7.24e-2)" "unprognostic (3.59e-3)" "unprognostic (2.03e-2)" "unprognostic (3.79e-2)" "unprognostic (1.31e-1)" "unprognostic (3.15e-1)" "unprognostic (5.19e-3)" "unprognostic (1.17e-1)" "unprognostic (7.33e-2)" "unprognostic (2.96e-1)" "unprognostic (3.25e-2)" "unprognostic (5.01e-2)" TMTC4 "FLJ14624, FLJ22153" ENSG00000125247 "Transmembrane O-mannosyltransferase targeting cadherins 4" Q5T4D3 13 100603625-100675093 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Transferase "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 245.3" "Group enriched" "Detected in all" 4 "committed oligodendrocyte precursor: 259.8;oligodendrocyte: 271.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016489, HPA057056" Approved Approved Vesicles NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 80: Oligodendrocytes - Myelination" 1 Vesicles "HPA016489: , HPA057056: " "unprognostic (4.04e-2)" "unprognostic (3.43e-2)" "unprognostic (9.76e-2)" "unprognostic (4.00e-2)" "unprognostic (2.11e-1)" "unprognostic (2.38e-1)" "unprognostic (8.04e-2)" "unprognostic (4.37e-1)" "unprognostic (1.73e-1)" "unprognostic (1.78e-3)" "unprognostic (1.77e-3)" "unprognostic (4.15e-1)" "unprognostic (4.57e-2)" "unprognostic (4.84e-2)" "unprognostic (6.63e-3)" "unprognostic (2.21e-1)" "unprognostic (2.55e-2)" "unprognostic (1.27e-1)" "unprognostic (1.51e-2)" "unprognostic (4.38e-1)" "unprognostic (4.38e-1)" "unprognostic (4.97e-2)" "unprognostic (8.94e-2)" "unprognostic (1.83e-1)" "unprognostic (4.52e-2)" "unprognostic (1.19e-2)" "unprognostic (6.20e-2)" "unprognostic (3.45e-1)" "unprognostic (1.55e-1)" "unprognostic (1.70e-2)" "unprognostic (6.00e-3)" TMUB1 "C7orf21, HOPS, SB144" ENSG00000164897 "Transmembrane and ubiquitin like domain containing 1" Q9BVT8 7 151081085-151083493 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 115.2;Cytotrophoblasts: 107.1;Enterocytes: 175.5;Esophageal apical cells: 123.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029429 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 19: Astrocytes - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 30 Nucleoplasm Cytosol "HPA029429: " "unprognostic (4.29e-2)" "unprognostic (2.52e-1)" "unprognostic (2.83e-2)" "potential prognostic unfavorable (1.59e-4)" "unprognostic (5.16e-2)" "unprognostic (2.09e-2)" "unprognostic (1.22e-2)" "unprognostic (1.70e-2)" "unprognostic (9.97e-2)" "unprognostic (7.17e-2)" "unprognostic (1.03e-3)" "unprognostic (5.72e-3)" "unprognostic (1.76e-1)" "unprognostic (4.45e-3)" "potential prognostic unfavorable (2.16e-5)" "unprognostic (1.00e-1)" "unprognostic (1.54e-2)" "unprognostic (6.82e-2)" "unprognostic (2.67e-1)" "unprognostic (8.26e-3)" "unprognostic (1.39e-1)" "unprognostic (3.99e-2)" "unprognostic (1.88e-1)" "unprognostic (1.21e-1)" "unprognostic (5.64e-2)" "unprognostic (6.63e-2)" "unprognostic (1.85e-1)" "unprognostic (4.09e-3)" "unprognostic (2.31e-1)" "unprognostic (7.96e-3)" "unprognostic (1.01e-2)" TMUB2 MGC3123 ENSG00000168591 "Transmembrane and ubiquitin like domain containing 2" Q71RG4 17 44186970-44191929 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 111.3;Syncytiotrophoblasts: 118.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043137 Approved Approved Vesicles,Cytosol NA NA "Cluster 41: Basophils - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 18 "Vesicles, Cytosol" "HPA043137: " "unprognostic (2.56e-1)" "unprognostic (2.28e-1)" "unprognostic (3.87e-2)" "unprognostic (3.87e-3)" "unprognostic (1.16e-1)" "unprognostic (1.06e-1)" "unprognostic (7.88e-3)" "unprognostic (2.37e-3)" "unprognostic (5.08e-2)" "unprognostic (1.75e-2)" "unprognostic (4.15e-3)" "unprognostic (8.17e-2)" "unprognostic (2.10e-2)" "potential prognostic unfavorable (2.45e-4)" "unprognostic (1.12e-2)" "unprognostic (2.19e-1)" "unprognostic (1.43e-1)" "unprognostic (1.52e-1)" "unprognostic (6.78e-2)" "unprognostic (2.20e-2)" "unprognostic (1.22e-1)" "unprognostic (2.78e-1)" "unprognostic (5.27e-2)" "unprognostic (2.43e-2)" "unprognostic (6.25e-3)" "unprognostic (8.43e-3)" "unprognostic (1.80e-1)" "unprognostic (7.86e-2)" "unprognostic (2.04e-1)" "unprognostic (2.28e-2)" "unprognostic (9.52e-3)" TMX1 "PDIA11, TMX, TXNDC, TXNDC1" ENSG00000139921 "Thioredoxin related transmembrane protein 1" Q9H3N1 14 51240162-51257655 "Predicted membrane proteins, Transporters" "Electron transport, Transport" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 203.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003085 Approved Supported "Nucleoli,Endoplasmic reticulum" "Intracellular and membrane" Transport NA NA 12000 "Cluster 13: Non-specific - Mitochondria" "Cluster 76: Non-specific - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 97: Non-specific - Cellular respiration" 51 "Endoplasmic reticulum" Nucleoli "HPA003085: " "unprognostic (6.69e-2)" "unprognostic (2.53e-1)" "unprognostic (1.29e-1)" "unprognostic (7.08e-3)" "unprognostic (1.40e-2)" "unprognostic (2.35e-1)" "unprognostic (1.03e-1)" "unprognostic (2.37e-1)" "unprognostic (7.93e-3)" "potential prognostic unfavorable (3.73e-5)" "unprognostic (6.07e-3)" "unprognostic (4.48e-2)" "unprognostic (1.67e-2)" "potential prognostic unfavorable (3.85e-5)" "unprognostic (3.54e-2)" "potential prognostic unfavorable (4.08e-5)" "unprognostic (4.30e-2)" "unprognostic (6.99e-3)" "unprognostic (6.81e-2)" "unprognostic (6.26e-2)" "unprognostic (7.88e-2)" "unprognostic (9.03e-3)" "unprognostic (4.79e-2)" "unprognostic (7.70e-2)" "unprognostic (2.58e-1)" "unprognostic (7.27e-2)" "unprognostic (2.87e-2)" "unprognostic (2.51e-2)" "unprognostic (2.30e-1)" "unprognostic (1.15e-1)" "unprognostic (1.99e-1)" TMX2 "PDIA12, TXNDC14" ENSG00000213593 "Thioredoxin related transmembrane protein 2" Q9Y320 11 57712593-57740973 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant, Intellectual disability, Lissencephaly, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 11 "Astrocytes: 46.9;Bergmann glia: 43.3;Brain excitatory neurons: 45.9;Brain inhibitory neurons: 48.2;Choroid plexus epithelial cells: 84.9;Ependymal cells: 35.8;Microglia: 37.0;Oligodendrocyte progenitor cells: 44.6;Oligodendrocytes: 53.0;Other brain neurons: 42.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040282, HPA063763" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 21: Non-specific - Metabolism" "Cluster 24: Non-specific - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" 141 "Nucleoplasm, Cytosol" "HPA040282: , HPA063763: " "unprognostic (4.45e-2)" "unprognostic (3.40e-3)" "unprognostic (5.48e-2)" "unprognostic (1.95e-1)" "unprognostic (1.12e-1)" "unprognostic (2.62e-1)" "unprognostic (3.71e-2)" "unprognostic (7.80e-2)" "unprognostic (1.83e-3)" "unprognostic (3.92e-1)" "potential prognostic favorable (2.13e-4)" "unprognostic (5.23e-2)" "unprognostic (1.64e-1)" "potential prognostic unfavorable (2.79e-4)" "unprognostic (5.07e-3)" "potential prognostic unfavorable (8.21e-4)" "unprognostic (2.79e-1)" "unprognostic (9.29e-2)" "unprognostic (1.66e-1)" "unprognostic (5.49e-2)" "unprognostic (1.75e-1)" "unprognostic (1.54e-2)" "unprognostic (3.15e-1)" "unprognostic (2.54e-1)" "unprognostic (5.64e-2)" "unprognostic (1.04e-2)" "unprognostic (8.52e-2)" "unprognostic (1.10e-1)" "unprognostic (5.63e-2)" "unprognostic (3.33e-1)" "unprognostic (1.36e-1)" TMX3 "FLJ20793, KIAA1830, PDIA13, TXNDC10" ENSG00000166479 "Thioredoxin related transmembrane protein 3" Q96JJ7 18 68673688-68715108 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014157 Uncertain "Intracellular and membrane" Enzyme NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 31: Non-specific - Transcription" "Cluster 13: Non-specific - Mixed function" "Cluster 7: Non-specific - Transcription" 14 "HPA014157: " "unprognostic (1.02e-1)" "unprognostic (2.53e-1)" "unprognostic (2.04e-1)" "unprognostic (6.70e-2)" "unprognostic (1.27e-1)" "unprognostic (2.35e-2)" "unprognostic (1.70e-1)" "unprognostic (1.77e-1)" "unprognostic (1.86e-2)" "unprognostic (1.56e-2)" "unprognostic (1.39e-1)" "unprognostic (4.25e-2)" "unprognostic (4.57e-2)" "unprognostic (7.84e-3)" "unprognostic (6.76e-2)" "unprognostic (3.47e-2)" "unprognostic (1.20e-1)" "unprognostic (2.86e-1)" "unprognostic (2.05e-1)" "unprognostic (2.59e-2)" "unprognostic (7.28e-2)" "unprognostic (5.21e-2)" "unprognostic (5.36e-2)" "unprognostic (2.20e-1)" "unprognostic (2.35e-1)" "unprognostic (1.36e-1)" "unprognostic (1.30e-2)" "unprognostic (5.48e-2)" "unprognostic (4.22e-2)" "unprognostic (7.58e-3)" "unprognostic (7.46e-2)" TMX4 "DJ971N18.2, KIAA1162, PDIA14, TXNDC13" ENSG00000125827 "Thioredoxin related transmembrane protein 4" Q9H1E5 20 7977346-8019805 "Predicted membrane proteins" "Electron transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 753.8;Late primary spermatocytes: 446.2;Late spermatids: 2315.9;Neutrophils: 548.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000399, HPA015752" Enhanced Approved "Nuclear membrane" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 35: Non-specific - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 69: Skin cancer - ECM organization" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 3 "Nuclear membrane" "HPA000399: , HPA015752: " "unprognostic (1.29e-1)" "unprognostic (6.15e-2)" "unprognostic (2.10e-2)" "unprognostic (2.85e-1)" "unprognostic (7.87e-3)" "unprognostic (1.45e-2)" "unprognostic (5.26e-2)" "unprognostic (4.61e-3)" "unprognostic (2.09e-1)" "unprognostic (2.94e-1)" "potential prognostic favorable (2.81e-5)" "unprognostic (7.54e-3)" "unprognostic (3.85e-2)" "unprognostic (1.31e-1)" "unprognostic (2.76e-2)" "unprognostic (9.67e-3)" "unprognostic (2.46e-2)" "potential prognostic unfavorable (6.19e-4)" "unprognostic (2.74e-3)" "unprognostic (2.06e-1)" "unprognostic (1.22e-1)" "unprognostic (1.55e-2)" "unprognostic (1.99e-2)" "unprognostic (1.25e-1)" "unprognostic (1.68e-1)" "unprognostic (4.13e-2)" "unprognostic (1.68e-1)" "unprognostic (2.67e-1)" "unprognostic (2.21e-1)" "unprognostic (5.88e-2)" "unprognostic (2.75e-2)" TNC "DFNA56, HXB, MGC167029, TN" ENSG00000041982 "Tenascin C" P24821 9 115019575-115118207 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 345.5;smooth muscle: 447.3" "Cell type enhanced" "Detected in many" "Astrocytes: 621.4;Breast myoepithelial cells: 187.7;Endometrial secretory cells: 663.1;Endometrial stromal cells: 255.5;Epididymal basal cells: 617.3;Fibroblasts: 209.7;Pericytes: 345.7;Respiratory basal cells: 169.5;Salivary basal cells: 174.7;Salivary myoepithelial cells: 386.4;Smooth muscle cells: 691.0;Vascular smooth muscle cells: 680.5" "Cell type enriched" "Detected in many" 19 "astrocyte: 995.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 378.1" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004592, HPA004823" Approved "Secreted to extracellular matrix" "Cell adhesion" NA NA 250000000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 19: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 4 "CAB004592: , HPA004823: " "unprognostic (3.68e-1)" "unprognostic (1.01e-1)" "unprognostic (2.54e-1)" "potential prognostic unfavorable (8.42e-4)" "unprognostic (7.59e-2)" "unprognostic (1.28e-1)" "unprognostic (1.61e-1)" "unprognostic (9.38e-3)" "unprognostic (2.36e-1)" "unprognostic (8.24e-3)" "unprognostic (9.10e-2)" "unprognostic (5.07e-2)" "unprognostic (1.33e-1)" "unprognostic (2.14e-1)" "unprognostic (3.14e-1)" "unprognostic (3.52e-2)" "unprognostic (5.21e-3)" "unprognostic (2.16e-1)" "unprognostic (2.44e-1)" "potential prognostic unfavorable (2.48e-4)" "unprognostic (2.08e-2)" "unprognostic (8.13e-2)" "unprognostic (2.91e-3)" "unprognostic (1.85e-1)" "unprognostic (3.27e-1)" "unprognostic (4.31e-3)" "unprognostic (6.53e-3)" "unprognostic (4.18e-3)" "unprognostic (1.36e-2)" "unprognostic (1.64e-1)" "unprognostic (9.72e-2)" TNF "DIF, TNF-alpha, TNFA, TNFSF2" ENSG00000232810 "Tumor necrosis factor" P01375 6 31575565-31578336 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 19.9;lymphoid tissue: 6.1" "Cell type enriched" "Detected in some" 5 "Microglia: 7.8" "Group enriched" "Detected in some" 144 "central nervous system macrophage: 11.6;leukocyte: 17.3" "Cancer enriched" "Detected in single" 4 "Ovary Serous Cystadenocarcinoma (TCGA): 2.1" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 73.4" "Group enriched" "Detected in all" 6 "granulocytes: 22.7;monocytes: 73.4;T-cells: 41.4" "Group enriched" "Detected in many" 5 "Leukemia: 13.7;lymphoma: 34.9" "Breast - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" CAB078469 Supported "Secreted to blood" Cytokine NA NA 10100 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 15: Bone marrow - Innate immune response" "Cluster 23: Choroid plexus - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 102: Non-specific - Mixed function" 73 "CAB078469: " "unprognostic (4.29e-2)" "unprognostic (3.12e-2)" "unprognostic (2.61e-1)" "unprognostic (1.68e-1)" "unprognostic (2.63e-2)" "unprognostic (1.56e-3)" TNFAIP1 "B12, B61, BTBD34, EDP1, MGC2317" ENSG00000109079 "TNF alpha induced protein 1" Q13829 17 28335602-28347009 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 99.8;Syncytiotrophoblasts: 93.2;Vascular endothelial cells: 79.3" "Cell type enhanced" "Detected in all" "endothelial cell: 50.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Lung - Endothelial cells, Prostate - Endothelial cells, Spleen - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013333, HPA014641" Uncertain Approved Nucleoli NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 23: Choroid plexus - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 53 Nucleoli "HPA013333: , HPA014641: " "unprognostic (1.25e-2)" "unprognostic (6.45e-2)" "unprognostic (1.86e-2)" "unprognostic (3.61e-3)" "unprognostic (8.98e-2)" "unprognostic (2.98e-1)" "unprognostic (2.54e-1)" "unprognostic (1.63e-1)" "unprognostic (1.46e-2)" "unprognostic (2.32e-1)" "validated prognostic favorable (4.46e-5)" "validated prognostic favorable (2.23e-5)" "unprognostic (2.17e-1)" "unprognostic (2.25e-1)" "unprognostic (4.05e-1)" "unprognostic (3.95e-2)" "unprognostic (3.35e-2)" "unprognostic (2.31e-1)" "unprognostic (8.07e-2)" "unprognostic (2.13e-2)" "unprognostic (2.56e-1)" "unprognostic (2.89e-2)" "unprognostic (5.27e-2)" "unprognostic (3.86e-2)" "unprognostic (4.02e-2)" "unprognostic (2.13e-2)" "unprognostic (1.83e-2)" "unprognostic (6.04e-2)" "unprognostic (4.37e-1)" "unprognostic (1.09e-1)" "unprognostic (7.30e-2)" TNFAIP2 "B94, EXOC3L3" ENSG00000185215 "TNF alpha induced protein 2" Q03169 14 103121476-103137439 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Angiogenesis, Differentiation" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "urinary bladder: 258.7" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 229.5;Endometrial secretory cells: 657.3;Epicardial cells: 188.8;Fallopian secretory cells: 420.9;Kupffer cells: 186.5;Macrophages: 220.1;monocytes: 297.7;Neutrophils: 442.2;Pancreatic duct cells: 224.9;Prostatic club cells: 230.3;Urothelial cells: 217.7" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 87.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 49.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB004598, HPA030624" Enhanced Approved "Nucleoplasm,Nuclear membrane,Golgi apparatus,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 20 "Golgi apparatus, Cytosol" "Nucleoplasm, Nuclear membrane" "CAB004598: , HPA030624: " "unprognostic (2.43e-2)" "unprognostic (4.41e-2)" "unprognostic (1.86e-2)" "unprognostic (4.97e-2)" "unprognostic (1.34e-1)" "unprognostic (2.29e-1)" "unprognostic (1.21e-2)" "potential prognostic unfavorable (1.68e-4)" "unprognostic (7.92e-2)" "unprognostic (9.25e-2)" "unprognostic (1.74e-2)" "unprognostic (1.50e-1)" "unprognostic (2.69e-2)" "unprognostic (3.09e-2)" "potential prognostic favorable (2.91e-4)" "unprognostic (1.41e-1)" "unprognostic (7.00e-3)" "unprognostic (6.84e-2)" "unprognostic (1.94e-1)" "unprognostic (8.40e-2)" "unprognostic (6.16e-2)" "unprognostic (5.62e-2)" "unprognostic (6.64e-2)" "unprognostic (2.04e-1)" "unprognostic (1.41e-1)" "unprognostic (6.99e-2)" "unprognostic (4.33e-1)" "potential prognostic favorable (2.36e-4)" "unprognostic (4.77e-2)" "unprognostic (6.58e-2)" "unprognostic (8.31e-2)" TNFAIP3 "A20, OTUD7C" ENSG00000118503 "TNF alpha induced protein 3" P21580 6 137867214-137883314 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Inflammatory response, Ubl conjugation pathway" "DNA-binding, Hydrolase, Multifunctional enzyme, Protease, Thiol protease, Transferase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 393.5;urinary bladder: 146.3" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 1903.0;Endometrial luminal cells: 1914.6;Endometrial secretory cells: 1179.1;Epididymal basal cells: 930.1;Hematopoietic stem cells: 984.0;Innate lymphoid cells: 2537.4;Mast cells: 2206.7;monocytes: 1643.0;Neutrophils: 5955.9;T-cells: 1132.9" "Cell type enhanced" "Detected in many" "endothelial cell: 51.5;leukocyte: 94.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Myeloma: 76.7" "Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002116 Approved Approved Centrosome,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 15: Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 55: Lymphoma - Immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 83 "Centrosome, Cytosol" "HPA002116: " "unprognostic (4.13e-1)" "unprognostic (6.61e-2)" "unprognostic (1.21e-2)" "unprognostic (2.30e-3)" "unprognostic (7.96e-2)" "unprognostic (1.51e-1)" "unprognostic (1.85e-1)" "unprognostic (1.90e-2)" "unprognostic (1.88e-1)" "unprognostic (2.26e-1)" "potential prognostic favorable (2.05e-4)" "unprognostic (1.95e-2)" "unprognostic (2.09e-2)" "unprognostic (5.60e-3)" "unprognostic (2.73e-1)" "unprognostic (2.15e-1)" "unprognostic (1.38e-2)" "unprognostic (1.20e-1)" "unprognostic (3.49e-2)" "unprognostic (5.38e-2)" "unprognostic (2.82e-2)" "unprognostic (1.04e-1)" "unprognostic (4.93e-3)" "unprognostic (1.49e-1)" "unprognostic (2.40e-2)" "potential prognostic favorable (9.31e-6)" "unprognostic (4.04e-3)" "unprognostic (6.24e-2)" "unprognostic (5.71e-3)" "unprognostic (4.85e-2)" "unprognostic (3.80e-1)" TNFAIP6 "TSG-6, TSG6" ENSG00000123610 "TNF alpha induced protein 6" P98066 2 151357592-151380046 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "urinary bladder: 181.9" "Cell type enhanced" "Detected in many" "Early spermatids: 567.8;Fibroblasts: 294.9;Late primary spermatocytes: 202.7;monocytes: 382.1;Neutrophil progenitors: 168.5;Neutrophils: 2232.9" "Group enriched" "Detected in some" 16 "astrocyte: 12.4;committed oligodendrocyte precursor: 24.8;fibroblast: 7.4;oligodendrocyte: 7.8;oligodendrocyte precursor cell: 12.4" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 62.8" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 22 "neutrophil: 183.6" "Lineage enriched" "Detected in many" 22 "granulocytes: 183.6" "Group enriched" "Detected in many" 6 "Bone cancer: 22.6;Kidney cancer: 58.1" "Spleen - Neutrophils_2, Stomach - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB032719, HPA050884" Uncertain "Secreted to blood" "Cell adhesion" NA NA 830000 "Cluster 4: Neutrophils - Degranulation" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 11 "CAB032719: , HPA050884: " "unprognostic (2.80e-1)" "unprognostic (1.52e-1)" "unprognostic (3.40e-3)" "unprognostic (6.04e-3)" "unprognostic (4.85e-2)" "unprognostic (2.60e-1)" "unprognostic (6.86e-3)" "potential prognostic unfavorable (5.56e-6)" "unprognostic (1.93e-3)" "potential prognostic favorable (1.03e-5)" "unprognostic (7.21e-2)" "unprognostic (8.42e-2)" "unprognostic (9.63e-2)" "unprognostic (3.06e-3)" "potential prognostic unfavorable (3.07e-4)" "unprognostic (2.04e-2)" "unprognostic (1.65e-2)" "unprognostic (7.59e-2)" "potential prognostic unfavorable (7.55e-4)" "unprognostic (8.53e-3)" "unprognostic (3.49e-2)" "unprognostic (2.81e-1)" "unprognostic (2.31e-2)" "unprognostic (1.26e-1)" "unprognostic (1.91e-3)" "unprognostic (4.01e-3)" "unprognostic (2.46e-2)" "potential prognostic unfavorable (3.85e-5)" TNFAIP8 "GG2-1, MDC-3.13, SCC-S2" ENSG00000145779 "TNF alpha induced protein 8" O95379 5 119268692-119399688 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 110.1" "Cell type enhanced" "Detected in many" "B-cells: 549.3;Choroid plexus epithelial cells: 460.6;monocytes: 665.4;Neutrophil progenitors: 2117.5;Neutrophils: 732.2;Pancreatic acinar cells: 1068.8;Syncytiotrophoblasts: 669.0" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 456.5;leukocyte: 654.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Myeloma: 126.8" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Macrophages, Breast - Adipocytes (Breast), Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054434, HPA057089" Uncertain Enhanced Nucleoplasm No Yes 110000 "Cluster 22: Eosinophils - Transcription" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 10 Nucleoplasm "HPA054434: , HPA057089: " "unprognostic (7.51e-2)" "unprognostic (4.05e-2)" "unprognostic (7.00e-3)" "unprognostic (2.38e-1)" "unprognostic (2.52e-1)" "unprognostic (1.71e-1)" "unprognostic (2.85e-2)" "unprognostic (7.80e-2)" "unprognostic (5.56e-2)" "unprognostic (1.10e-2)" "potential prognostic favorable (3.99e-5)" "unprognostic (6.34e-3)" "unprognostic (1.81e-1)" "unprognostic (2.05e-2)" "unprognostic (3.16e-1)" "unprognostic (1.29e-1)" "unprognostic (7.86e-2)" "unprognostic (3.90e-2)" "unprognostic (2.77e-1)" "unprognostic (1.14e-1)" "unprognostic (1.25e-1)" "unprognostic (2.96e-2)" "unprognostic (6.07e-2)" "unprognostic (1.37e-1)" "unprognostic (7.35e-2)" "unprognostic (1.51e-1)" "unprognostic (3.15e-1)" "unprognostic (1.49e-2)" "unprognostic (4.35e-3)" "unprognostic (6.78e-3)" "unprognostic (1.79e-1)" TNFAIP8L1 MGC17791 ENSG00000185361 "TNF alpha induced protein 8 like 1" Q8WVP5 19 4639516-4655568 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 29.3;liver: 33.1" "Group enriched" "Detected in many" 4 "Early spermatids: 406.6;Late spermatids: 1467.0" "Cell type enhanced" "Detected in many" "pericyte: 30.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Spleen - Endothelial cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA Yes "Cluster 45: Eosinophils - Unknown function" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 51: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 14 "unprognostic (1.38e-1)" "unprognostic (7.83e-2)" "potential prognostic favorable (7.90e-4)" "unprognostic (9.16e-2)" "unprognostic (3.29e-1)" "unprognostic (9.76e-2)" "unprognostic (2.18e-1)" "unprognostic (1.49e-1)" "unprognostic (4.20e-2)" "unprognostic (1.56e-1)" "unprognostic (6.02e-3)" "unprognostic (1.73e-3)" "unprognostic (1.28e-2)" "unprognostic (9.44e-2)" "unprognostic (4.12e-3)" "unprognostic (2.63e-2)" "potential prognostic unfavorable (3.84e-5)" "unprognostic (2.34e-1)" "unprognostic (3.42e-1)" "unprognostic (4.38e-1)" "unprognostic (6.55e-2)" "unprognostic (1.12e-2)" "unprognostic (2.74e-1)" "unprognostic (3.72e-2)" "unprognostic (2.02e-1)" "unprognostic (1.87e-2)" "unprognostic (1.99e-1)" "unprognostic (2.22e-1)" "unprognostic (1.56e-1)" "unprognostic (1.40e-1)" "unprognostic (1.70e-1)" TNFAIP8L2 FLJ23467 ENSG00000163154 "TNF alpha induced protein 8 like 2" Q6P589 1 151156649-151159749 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 38.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 7 "Leukemia: 29.2;lymphoma: 8.9" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Spleen - Macrophages, Stomach - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA062742 Approved Vesicles NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 2 Vesicles "HPA062742: " "unprognostic (2.53e-1)" "potential prognostic favorable (4.88e-4)" "unprognostic (1.91e-1)" "unprognostic (8.74e-2)" "unprognostic (2.07e-2)" "unprognostic (2.69e-1)" "unprognostic (2.05e-1)" "unprognostic (1.07e-1)" "unprognostic (5.70e-3)" "unprognostic (5.15e-2)" "unprognostic (1.18e-2)" "unprognostic (2.31e-1)" "unprognostic (2.01e-2)" "unprognostic (3.74e-2)" "unprognostic (6.45e-2)" "potential prognostic favorable (9.85e-4)" "unprognostic (6.32e-2)" "unprognostic (1.92e-1)" "unprognostic (2.05e-1)" "unprognostic (1.28e-1)" "unprognostic (3.23e-1)" "unprognostic (7.25e-2)" "unprognostic (4.76e-2)" "unprognostic (1.85e-1)" "unprognostic (5.50e-2)" "unprognostic (1.56e-1)" "unprognostic (1.36e-2)" "unprognostic (2.76e-1)" "unprognostic (5.05e-2)" "unprognostic (2.24e-2)" "unprognostic (1.16e-1)" TNFAIP8L3 FLJ41287 ENSG00000183578 "TNF alpha induced protein 8 like 3" Q5GJ75 15 51056598-51105276 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 77.7;fallopian tube: 53.7;smooth muscle: 79.2" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 168.5;Esophageal apical cells: 89.8;Fallopian tube ciliated cells: 33.0;Hepatic stellate cells: 25.8;Lymphatic endothelial cells: 62.6;Smooth muscle cells: 102.0;Thymic myoid cells: 32.6;Vascular smooth muscle cells: 30.4" "Cell type enhanced" "Detected in many" "CGE interneuron: 56.2;hippocampal CA4: 64.3;LAMP5-LHX6 and Chandelier: 44.4" "Cancer enriched" "Detected in all" 5 "Kidney Chromophobe (TCGA): 53.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 7.3" "Adipose subcutaneous - Smooth muscle cells, Prostate - Fibroblasts, Skin - Keratinocyte (granular), Spleen - Fibroblasts_1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA077484 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 75: Ovary - Mixed function" "Cluster 29: Forebrain - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 3: Early primary spermatocytes - Early meiosis" 2 Cytosol Nucleoplasm "HPA077484: " "unprognostic (5.29e-2)" "unprognostic (1.13e-1)" "unprognostic (3.96e-2)" "unprognostic (6.08e-2)" "unprognostic (8.44e-3)" "unprognostic (1.42e-1)" "unprognostic (5.83e-2)" "unprognostic (2.62e-1)" "unprognostic (2.32e-2)" "unprognostic (1.79e-1)" "unprognostic (2.93e-1)" "unprognostic (6.19e-2)" "unprognostic (1.78e-2)" "unprognostic (1.16e-2)" "unprognostic (1.39e-1)" "unprognostic (2.07e-2)" "unprognostic (2.05e-2)" "unprognostic (6.36e-3)" "potential prognostic unfavorable (6.05e-4)" "potential prognostic unfavorable (8.83e-4)" "unprognostic (1.76e-1)" "unprognostic (2.85e-2)" "unprognostic (1.18e-1)" "unprognostic (1.52e-1)" "unprognostic (1.23e-1)" "unprognostic (1.22e-1)" "unprognostic (1.47e-2)" "unprognostic (1.09e-1)" "unprognostic (5.20e-3)" "unprognostic (1.72e-1)" TNFRSF10A "Apo2, CD261, DR4, TRAILR-1, TRAILR1" ENSG00000104689 "TNF receptor superfamily member 10a" O00220 8 23190452-23225102 "Cancer-related genes, CD markers, Predicted membrane proteins" Apoptosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "B-cells: 50.6;Basal keratinocytes: 58.6;Endometrial luminal cells: 50.9;Ocular epithelial cells: 61.1;Suprabasal keratinocytes: 63.0;Vascular endothelial cells: 52.8" "Group enriched" "Detected in some" 8 "central nervous system macrophage: 19.2;endothelial cell: 53.1;leukocyte: 47.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Heart muscle - Endothelial cells, Pituitary gland - Endothelial cells, Skeletal muscle - Endothelial cells, Spleen - B-cells (Spleen), Testis - Endothelial cells" HPA054475 Approved NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 47: Endothelial cells - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 20 "HPA054475: " "unprognostic (3.64e-1)" "unprognostic (1.47e-1)" "unprognostic (9.51e-2)" "unprognostic (4.24e-2)" "unprognostic (7.36e-2)" "unprognostic (2.32e-1)" "unprognostic (2.00e-1)" "unprognostic (3.95e-3)" "unprognostic (7.32e-2)" "unprognostic (9.03e-2)" "validated prognostic favorable (2.74e-9)" "validated prognostic favorable (1.65e-4)" "potential prognostic favorable (1.49e-4)" "unprognostic (2.82e-2)" "unprognostic (4.91e-2)" "unprognostic (1.54e-1)" "unprognostic (1.08e-2)" "unprognostic (6.01e-3)" "unprognostic (2.37e-2)" "unprognostic (2.03e-1)" "unprognostic (7.82e-3)" "potential prognostic unfavorable (2.42e-4)" "unprognostic (5.95e-3)" "unprognostic (1.44e-1)" "unprognostic (6.93e-3)" "unprognostic (8.63e-2)" "unprognostic (2.36e-1)" "unprognostic (7.40e-2)" "unprognostic (1.17e-2)" "unprognostic (3.81e-1)" "unprognostic (1.25e-1)" TNFRSF10B "CD262, DR5, KILLER, TRAIL-R2, TRAILR2, TRICK2A, TRICKB" ENSG00000120889 "TNF receptor superfamily member 10b" O14763 8 23020133-23069031 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" Apoptosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 311.7;Enterocytes: 370.6;Urothelial cells: 395.3" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 95.7;choroid plexus epithelial cell: 62.6;endothelial cell: 114.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Endothelial cells" HPA023625 Approved NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 28: Liver & Adrenal gland - Secretion" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 20 "HPA023625: " "unprognostic (5.59e-2)" "unprognostic (3.36e-1)" "potential prognostic favorable (4.26e-4)" "unprognostic (2.01e-3)" "unprognostic (4.24e-3)" "unprognostic (1.31e-1)" "unprognostic (8.81e-2)" "potential prognostic unfavorable (1.12e-4)" "unprognostic (2.07e-1)" "unprognostic (5.12e-1)" "unprognostic (1.06e-2)" "unprognostic (1.87e-2)" "unprognostic (7.64e-2)" "unprognostic (1.37e-1)" "unprognostic (1.51e-2)" "unprognostic (1.70e-1)" "unprognostic (1.08e-2)" "unprognostic (4.23e-3)" "unprognostic (4.12e-1)" "unprognostic (5.84e-2)" "unprognostic (3.37e-1)" "unprognostic (1.54e-3)" "unprognostic (2.53e-2)" "unprognostic (6.68e-2)" "unprognostic (1.19e-2)" "unprognostic (3.11e-2)" "unprognostic (1.93e-1)" "unprognostic (1.01e-1)" "unprognostic (4.65e-2)" "unprognostic (5.41e-2)" "unprognostic (1.19e-1)" TNFRSF10C "CD263, DcR1, LIT, TRAILR3, TRID" ENSG00000173535 "TNF receptor superfamily member 10c" O14798 8 23102921-23117445 "Cancer-related genes, CD markers, Predicted membrane proteins" Apoptosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.8;lymphoid tissue: 22.4" "Cell type enriched" "Detected in some" 8 "Neutrophils: 209.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Thyroid Carcinoma (TCGA): 17.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 3204.8" "Lineage enriched" "Detected in many" 120 "granulocytes: 3204.8" "Low cancer specificity" "Detected in many" "Adipose visceral - Neutrophils, Liver - Neutrophils, Lung - Neutrophils_2, Spleen - Neutrophils_2" CAB025635 Enhanced NA NA 730000 "Cluster 21: Neutrophils - Unknown function" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 34: Testis cancer - Unknown function" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 41 "CAB025635: " "unprognostic (2.20e-2)" "unprognostic (4.39e-2)" "unprognostic (2.12e-1)" "unprognostic (8.87e-2)" "unprognostic (1.82e-2)" "unprognostic (2.76e-2)" "unprognostic (4.14e-3)" "unprognostic (1.94e-2)" "unprognostic (8.98e-2)" "unprognostic (5.88e-3)" "unprognostic (3.45e-3)" "potential prognostic favorable (3.92e-5)" "unprognostic (1.35e-2)" "unprognostic (5.39e-2)" "unprognostic (7.40e-2)" "potential prognostic favorable (1.25e-4)" "unprognostic (2.00e-1)" "unprognostic (3.57e-3)" "unprognostic (4.07e-2)" "unprognostic (3.14e-2)" "unprognostic (1.52e-1)" "unprognostic (2.32e-1)" "potential prognostic unfavorable (2.66e-4)" "unprognostic (2.49e-2)" "unprognostic (2.33e-1)" "unprognostic (3.15e-1)" "unprognostic (2.31e-1)" "unprognostic (2.46e-1)" "unprognostic (1.43e-1)" "unprognostic (2.50e-2)" "unprognostic (4.25e-2)" TNFRSF10D "CD264, DcR2, TRAILR4, TRUNDD" ENSG00000173530 "TNF receptor superfamily member 10d" Q9UBN6 8 23135588-23164027 "Cancer-related genes, CD markers, Predicted membrane proteins" Apoptosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Colonocytes: 152.1;Enterocytes: 208.8;Lymphatic endothelial cells: 144.5;Ovarian stromal cells: 115.3;Salivary myoepithelial cells: 152.8;Vascular endothelial cells: 308.3" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 53.2;endothelial cell: 106.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose visceral - Neutrophils" HPA070971 Approved "Plasma membrane,Actin filaments" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 21 "Plasma membrane, Actin filaments" "HPA070971: " "unprognostic (5.60e-2)" "unprognostic (1.52e-1)" "unprognostic (6.50e-2)" "potential prognostic unfavorable (9.48e-4)" "unprognostic (1.14e-1)" "unprognostic (1.59e-1)" "unprognostic (1.30e-3)" "unprognostic (4.55e-2)" "unprognostic (1.60e-1)" "unprognostic (1.10e-2)" "potential prognostic favorable (3.47e-4)" "unprognostic (1.31e-3)" "unprognostic (2.41e-2)" "unprognostic (1.40e-1)" "unprognostic (5.14e-2)" "unprognostic (2.01e-1)" "unprognostic (9.02e-3)" "unprognostic (1.86e-2)" "unprognostic (8.74e-2)" "unprognostic (2.75e-2)" "unprognostic (1.18e-1)" "unprognostic (8.80e-3)" "unprognostic (1.25e-3)" "unprognostic (3.06e-2)" "unprognostic (3.86e-1)" "unprognostic (2.67e-2)" "unprognostic (2.82e-1)" "unprognostic (2.38e-1)" "unprognostic (9.04e-3)" "unprognostic (1.46e-2)" "unprognostic (1.70e-1)" TNFRSF11A "CD265, FEO, LOH18CR1, ODFR, PDB2, RANK, TRANCE-R" ENSG00000141655 "TNF receptor superfamily member 11a" Q9Y6Q6 18 62325287-62391288 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Deafness, Disease variant, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 28.5;salivary gland: 23.7" "Cell type enhanced" "Detected in many" "Colonocytes: 60.9;Corticotrophs: 41.7;Enteric stem cells: 66.5;Enteric transient amplifying cells: 55.1;Innate lymphoid cells: 51.0;Kupffer cells: 43.0;Lacrimal acinar cells: 85.1;Lactotrophs: 64.2;Lymphatic endothelial cells: 63.5;Microglia: 42.6;Pancreatic duct cells: 47.7;Salivary acinar cells: 96.9;Thyrotrophs: 46.7" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 61.8" "Cancer enhanced" "Detected in many" "Stomach Adenocarcinoma (TCGA): 15.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "NK-cell: 2.3" "Lineage enriched" "Detected in single" 8 "NK-cells: 2.3" "Cancer enhanced" "Detected in many" "Gastric cancer: 9.7" "Adipose subcutaneous - Macrophages, Adrenal gland - Macrophages, Kidney - Macrophages, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Corticotropes, Skeletal muscle - Macrophages, Testis - Spermatogonia, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB010391, HPA047976" Approved Supported "Plasma membrane,Cytosol" "Intracellular and membrane" Receptor NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 50: Lymphoma - Unknown function" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 9 "Plasma membrane" Cytosol "CAB010391: , HPA047976: " "unprognostic (2.06e-2)" "unprognostic (1.98e-1)" "unprognostic (1.07e-1)" "unprognostic (2.17e-1)" "unprognostic (1.11e-2)" "unprognostic (1.43e-3)" "unprognostic (1.98e-2)" "unprognostic (1.26e-1)" "unprognostic (7.99e-2)" "unprognostic (3.58e-3)" "unprognostic (3.19e-2)" "potential prognostic unfavorable (6.59e-4)" "potential prognostic unfavorable (8.41e-4)" "unprognostic (1.87e-2)" "unprognostic (1.57e-1)" "unprognostic (2.65e-2)" "unprognostic (2.56e-2)" "unprognostic (1.84e-2)" "unprognostic (1.41e-2)" "unprognostic (1.88e-1)" "unprognostic (1.13e-2)" "potential prognostic unfavorable (2.37e-5)" "unprognostic (4.96e-2)" "unprognostic (9.92e-2)" "unprognostic (8.84e-2)" "unprognostic (1.47e-1)" TNFRSF11B "OCIF, OPG, TR1" ENSG00000164761 "TNF receptor superfamily member 11b" O00300 8 118923557-118951885 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" Apoptosis Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "blood vessel: 192.4;thyroid gland: 95.4" "Cell type enriched" "Detected in many" 18 "Breast lactating cells: 1608.8" "Cell type enhanced" "Detected in many" "Bergmann glia: 32.6;ependymal cell: 37.6;mammillary body: 45.3" "Cancer enhanced" "Detected in all" "Kidney Renal Papillary Cell Carcinoma (TCGA): 81.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 40 "plasmacytoid DC: 4.0" "Lineage enriched" "Detected in single" 40 "dendritic cells: 4.0" "Cancer enhanced" "Detected in many" "ovarian cancer: 54.6" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034939, HPA058613" Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus" "Secreted in other tissues" Receptor NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 4: Breast lactating luminal cells - Lactation" 5 "Golgi apparatus" "Nucleoplasm, Nucleoli" "CAB034939: , HPA058613: " "unprognostic (8.22e-2)" "unprognostic (1.22e-2)" "unprognostic (8.14e-2)" "unprognostic (1.03e-2)" "unprognostic (1.11e-1)" "unprognostic (8.01e-2)" "validated prognostic unfavorable (5.82e-4)" "validated prognostic unfavorable (9.54e-4)" "potential prognostic favorable (9.17e-4)" "unprognostic (3.31e-3)" "potential prognostic favorable (4.87e-5)" "unprognostic (1.64e-1)" "unprognostic (8.74e-2)" "unprognostic (2.68e-3)" "unprognostic (3.75e-1)" "unprognostic (3.45e-1)" "unprognostic (2.32e-1)" "unprognostic (6.64e-3)" "unprognostic (4.38e-1)" "unprognostic (2.54e-1)" "unprognostic (1.37e-2)" "unprognostic (4.46e-2)" "unprognostic (1.50e-1)" "unprognostic (9.19e-2)" "unprognostic (7.29e-2)" "unprognostic (1.53e-1)" "unprognostic (2.86e-1)" "unprognostic (2.78e-2)" "unprognostic (1.33e-1)" "unprognostic (1.29e-3)" "unprognostic (2.27e-2)" TNFRSF12A "CD266, FN14, TweakR" ENSG00000006327 "TNF receptor superfamily member 12A" Q9NP84 16 3018445-3022383 "Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Apoptosis, Cell adhesion, Differentiation" "Developmental protein, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 534.6;Basal keratinocytes: 436.7;Breast secretory cells: 295.5;Endometrial secretory cells: 362.0;Epididymal basal cells: 901.0;Epididymal efferent duct absorptive cells: 396.6;Epididymal efferent duct ciliated cells: 449.5;Fallopian secretory cells: 706.9;Pancreatic duct cells: 587.9;Smooth muscle cells: 301.3" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 10.9;lower rhombic lip: 10.7;vascular associated smooth muscle cell: 20.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "eosinophil: 140.0;neutrophil: 103.3" "Lineage enriched" "Detected in many" 10 "granulocytes: 140.0" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Ductal cells" "Low region specificity" "Detected in all" HPA007853 Approved Approved "Plasma membrane,Cytosol" NA Yes 680000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 70: Non-specific - Protein processing" "Cluster 12: Non-specific - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 51: Secretory epithelial cells - Mixed function" 7 "Plasma membrane, Cytosol" "HPA007853: " "unprognostic (9.13e-2)" "unprognostic (2.88e-2)" "unprognostic (1.24e-1)" "unprognostic (2.30e-3)" "unprognostic (1.32e-1)" "unprognostic (3.51e-1)" "unprognostic (1.68e-2)" "potential prognostic unfavorable (3.13e-4)" "potential prognostic unfavorable (2.63e-4)" "unprognostic (7.19e-2)" "unprognostic (1.25e-3)" "potential prognostic unfavorable (7.22e-5)" "unprognostic (2.44e-2)" "unprognostic (4.27e-3)" "unprognostic (6.70e-2)" "unprognostic (3.40e-2)" "unprognostic (3.47e-2)" "unprognostic (1.70e-3)" "unprognostic (8.21e-3)" "unprognostic (2.26e-1)" "unprognostic (4.46e-2)" "unprognostic (3.16e-3)" "unprognostic (3.11e-2)" "unprognostic (3.80e-1)" "unprognostic (2.57e-1)" "unprognostic (1.16e-1)" "potential prognostic favorable (4.95e-4)" "unprognostic (1.77e-2)" "unprognostic (2.15e-1)" "unprognostic (1.83e-3)" "unprognostic (3.35e-1)" TNFRSF13B "CD267, IGAD2, TACI" ENSG00000240505 "TNF receptor superfamily member 13B" O14836 17 16929816-16972118 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "intestine: 16.7;lymphoid tissue: 29.7;skeletal muscle: 58.7" "Group enriched" "Detected in some" 13 "B-cells: 133.1;Plasma cells: 177.0" "Cell type enriched" "Detected in single" 5 "leukocyte: 2.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 41 "memory B-cell: 131.4;naive B-cell: 52.1" "Lineage enriched" "Detected in many" 59 "B-cells: 131.4" "Group enriched" "Detected in some" 6 "lymphoma: 69.1;Myeloma: 110.9" "Adipose subcutaneous - Plasma cells, Breast - Plasma cells, Minor Salivary Gland - Plasma cells, Spleen - B-cells (Spleen), Stomach - Plasma cells, Thyroid gland - Plasma cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA030453 Uncertain NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 6: Non-specific - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 10 "HPA030453: " "unprognostic (4.28e-1)" "unprognostic (4.98e-2)" "unprognostic (1.91e-2)" "potential prognostic favorable (7.34e-4)" "unprognostic (7.15e-2)" "unprognostic (1.33e-1)" "unprognostic (2.91e-1)" "unprognostic (1.83e-1)" "unprognostic (2.24e-1)" "unprognostic (3.25e-1)" TNFRSF13C "BAFFR, CD268" ENSG00000159958 "TNF receptor superfamily member 13C" Q96RJ3 22 41922032-41926806 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "intestine: 31.4;lymphoid tissue: 55.6" "Group enriched" "Detected in some" 5 "B-cells: 271.1;Microglia: 71.0" "Cell type enriched" "Detected in some" 13 "central nervous system macrophage: 72.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 39 "memory B-cell: 22.3;naive B-cell: 28.8" "Lineage enriched" "Detected in single" 44 "B-cells: 28.8" "Group enriched" "Detected in many" 5 "Leukemia: 10.0;lymphoma: 25.8" "Heart muscle - Cardiomyocytes, Lung - B-cells (Lung), Spleen - B-cells (Spleen)" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA003246, CAB008380" Enhanced NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 2 "CAB008380: , HPA003246: " "unprognostic (3.84e-2)" "unprognostic (3.61e-3)" "unprognostic (7.12e-2)" "potential prognostic favorable (1.81e-4)" "unprognostic (1.31e-1)" "unprognostic (5.65e-2)" "unprognostic (1.37e-2)" "potential prognostic favorable (1.54e-5)" "unprognostic (6.82e-3)" "unprognostic (1.20e-3)" "unprognostic (1.35e-1)" "unprognostic (6.08e-2)" "unprognostic (7.03e-3)" "unprognostic (2.29e-1)" "unprognostic (9.67e-2)" "unprognostic (2.49e-3)" "unprognostic (2.03e-1)" "unprognostic (1.15e-1)" "unprognostic (1.31e-1)" "unprognostic (1.17e-1)" TNFRSF14 "ATAR, CD270, HVEA, HVEM, LIGHTR, TR2" ENSG00000157873 "TNF receptor superfamily member 14" Q92956 1 2555639-2565382 "Cancer-related genes, CD markers, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 23.5;Distal convoluted tubule cells: 20.0;Loop of henle epithelial cells: 15.1;Papillary tip epithelial cells: 31.7;Podocytes: 28.1;Proximal tubule cells: 92.7;Renal collecting duct intercalated cells: 31.3;Renal collecting duct principal cells: 30.6;Renal connecting tubule cells: 24.5" "Cell type enhanced" "Detected in many" "endothelial cell: 54.1;leukocyte: 56.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "skin cancer: 17.5" "HPA006404, CAB026150, CAB030007, CAB080525, CAB080526" Approved Supported "Plasma membrane,Cytosol" NA NA 150000 "Cluster 33: Non-specific - ATP binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 12: Non-specific - Vasculature" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 88: Proximal tubular cells - Transmembrane transport" 12 "Plasma membrane, Cytosol" "CAB026150: , CAB030007: , CAB080525: , CAB080526: , HPA006404: " "unprognostic (1.19e-1)" "unprognostic (4.43e-2)" "unprognostic (1.44e-2)" "unprognostic (2.03e-1)" "unprognostic (1.76e-2)" "unprognostic (1.99e-3)" "unprognostic (1.81e-2)" "potential prognostic unfavorable (1.70e-4)" "unprognostic (3.17e-2)" "unprognostic (1.28e-1)" "potential prognostic favorable (5.65e-6)" "unprognostic (4.32e-3)" "unprognostic (1.79e-1)" "unprognostic (3.05e-1)" "unprognostic (9.33e-2)" "unprognostic (7.65e-2)" "unprognostic (4.34e-2)" "unprognostic (7.40e-2)" "unprognostic (2.37e-1)" "unprognostic (1.26e-1)" "unprognostic (8.82e-3)" "unprognostic (2.01e-2)" "unprognostic (2.07e-1)" "unprognostic (1.69e-2)" "unprognostic (2.08e-1)" "unprognostic (2.81e-1)" "unprognostic (1.32e-1)" "unprognostic (3.93e-1)" "unprognostic (1.46e-1)" "unprognostic (1.78e-1)" "unprognostic (7.11e-3)" TNFRSF17 "BCM, BCMA, CD269, TNFRSF13A" ENSG00000048462 "TNF receptor superfamily member 17" Q02223 16 11965210-11968068 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 27.3;lymphoid tissue: 44.8;stomach 1: 23.0" "Cell type enriched" "Detected in some" 20 "Plasma cells: 566.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 63 "memory B-cell: 125.4;naive B-cell: 109.1;plasmacytoid DC: 103.5" "Group enriched" "Detected in many" 64 "B-cells: 125.4;dendritic cells: 103.5" "Cancer enriched" "Detected in some" 9 "Myeloma: 608.0" "Adipose visceral - Plasma cells, Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Testis - Early spermatids, Thyroid gland - Plasma cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA010569 Approved "Golgi apparatus,Mitotic spindle" Yes NA 1300000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 34: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 67: Plasma cells - Plasma cell differentiation" 4 "Golgi apparatus" "Mitotic spindle" "HPA010569: " "unprognostic (2.60e-1)" "potential prognostic favorable (4.93e-6)" "unprognostic (2.36e-1)" "unprognostic (1.52e-2)" "unprognostic (2.36e-2)" "unprognostic (7.16e-2)" "potential prognostic favorable (2.70e-6)" "unprognostic (3.19e-3)" "unprognostic (1.48e-1)" "potential prognostic unfavorable (1.56e-4)" "unprognostic (6.38e-3)" "unprognostic (9.62e-3)" "unprognostic (2.80e-1)" "unprognostic (8.38e-2)" "unprognostic (1.30e-2)" "unprognostic (3.65e-1)" "unprognostic (4.26e-3)" "unprognostic (4.10e-1)" "unprognostic (9.75e-2)" "unprognostic (1.45e-1)" "unprognostic (1.65e-1)" "unprognostic (2.65e-2)" "unprognostic (1.19e-1)" TNFRSF18 "AITR, CD357, GITR" ENSG00000186891 "TNF receptor superfamily member 18" Q9Y5U5 1 1203508-1206592 "CD markers, Predicted membrane proteins, Predicted secreted proteins" Apoptosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 36.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 123.2;Endometrial secretory cells: 96.9;Innate lymphoid cells: 224.2;NK-cells: 118.4;Plasma cells: 144.9;Suprabasal keratinocytes: 84.6;T-cells: 44.5;Thymocytes: 94.0" "Cell type enhanced" "Detected in some" "leukocyte: 9.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "NK-cell: 184.9;T-reg: 72.0" "Group enriched" "Detected in many" 11 "NK-cells: 184.9;T-cells: 72.0" "Cancer enhanced" "Detected in many" "lymphoma: 36.8;Myeloma: 25.5" "Minor Salivary Gland - Plasma cells, Skin - Keratinocyte (other), Stomach - Plasma cells" "Not detected" "Not detected" "Region enriched" "Detected in single" 8 "basal ganglia: 1.2" HPA008025 Approved "Secreted to blood" Receptor NA NA "Cluster 1: T-cells - Unknown function" "Cluster 58: Skin - Keratinization" "Cluster 37: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 4 "HPA008025: " "unprognostic (9.59e-2)" "potential prognostic favorable (5.58e-4)" "unprognostic (2.30e-2)" "unprognostic (3.88e-1)" "unprognostic (1.88e-1)" "potential prognostic favorable (4.16e-5)" "unprognostic (1.19e-3)" "potential prognostic favorable (9.25e-5)" "potential prognostic unfavorable (7.90e-6)" "unprognostic (7.15e-3)" "unprognostic (1.19e-1)" "unprognostic (1.91e-2)" "unprognostic (2.30e-1)" "unprognostic (2.22e-1)" "unprognostic (2.87e-2)" "unprognostic (2.68e-2)" "unprognostic (6.13e-2)" "unprognostic (1.15e-1)" "unprognostic (7.62e-2)" "unprognostic (2.60e-1)" "unprognostic (2.22e-3)" "unprognostic (3.38e-1)" "unprognostic (2.21e-1)" "unprognostic (2.90e-2)" "unprognostic (1.30e-2)" "unprognostic (2.68e-3)" "unprognostic (1.75e-1)" "unprognostic (3.49e-1)" "unprognostic (3.61e-2)" TNFRSF19 "TAJ, TAJ-alpha, TRADE, TROY" ENSG00000127863 "TNF receptor superfamily member 19" Q9NS68 13 23570370-23676104 "Plasma proteins, Predicted membrane proteins" Apoptosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 52.1;skin 1: 101.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 158.9;Distal convoluted tubule cells: 155.5;Lacrimal acinar cells: 331.5;Pituicytes/FSCs: 228.1;Prostatic glandular cells: 252.6;Respiratory ciliated cells: 236.9;Salivary acinar cells: 584.5" "Cell type enriched" "Detected in many" 4 "fibroblast: 391.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.3" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Rhabdoid: 54.7;skin cancer: 48.0" "Adrenal gland - Adrenal cortex cells, Colon - Enteric glia cells, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Skeletal muscle - Fibroblasts, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010135 Approved "Nucleoplasm,Golgi apparatus" No No 8000 "Cluster 16: Non-specific - Cell proliferation" "Cluster 37: Skin - Keratinization" "Cluster 39: Astrocytes - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 4 "Golgi apparatus" Nucleoplasm "HPA010135: " "unprognostic (2.78e-2)" "unprognostic (1.12e-1)" "unprognostic (1.15e-1)" "unprognostic (1.21e-1)" "unprognostic (3.51e-2)" "unprognostic (7.40e-2)" "unprognostic (1.49e-1)" "unprognostic (3.82e-2)" "unprognostic (9.87e-3)" "unprognostic (1.85e-1)" "potential prognostic favorable (5.39e-9)" "unprognostic (5.40e-3)" "unprognostic (4.38e-3)" "unprognostic (8.09e-2)" "unprognostic (5.21e-2)" "potential prognostic favorable (2.09e-4)" "unprognostic (6.18e-2)" "unprognostic (2.27e-1)" "unprognostic (2.36e-1)" "unprognostic (5.13e-1)" "unprognostic (1.21e-2)" "unprognostic (4.94e-2)" "unprognostic (1.18e-1)" "unprognostic (9.77e-2)" "unprognostic (3.29e-2)" "unprognostic (1.74e-1)" "unprognostic (3.26e-1)" "unprognostic (2.28e-2)" "unprognostic (4.54e-2)" "unprognostic (2.11e-3)" "unprognostic (8.55e-2)" TNFRSF1A "CD120a, TNF-R, TNF-R-I, TNF-R55, TNFAR, TNFR1, TNFR60" ENSG00000067182 "TNF receptor superfamily member 1A" P19438 12 6328757-6342114 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Apoptosis, Host-virus interaction" Receptor "Amyloidosis, Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 370.0;Esophageal apical cells: 290.4;Hofbauer cells: 287.7;Neutrophils: 473.5" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 98.7;leukocyte: 78.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 454.7" "Group enriched" "Detected in many" 4 "dendritic cells: 116.0;granulocytes: 454.7;monocytes: 152.3" "Low cancer specificity" "Detected in all" "Pituitary gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004102, CAB010309" Approved "Secreted to blood" Receptor NA NA 17700 850000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 28: Liver & Adrenal gland - Secretion" "Cluster 39: Astrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 24: Neutrophils - Innate immunity signal integration" 54 "CAB010309: , HPA004102: " "unprognostic (1.10e-1)" "unprognostic (7.91e-2)" "unprognostic (2.45e-1)" "unprognostic (7.41e-3)" "unprognostic (2.64e-2)" "unprognostic (5.28e-2)" "unprognostic (4.83e-3)" "potential prognostic unfavorable (1.94e-4)" "unprognostic (2.80e-3)" "unprognostic (1.03e-3)" "unprognostic (5.66e-3)" "unprognostic (3.12e-1)" "unprognostic (5.44e-3)" "unprognostic (1.50e-2)" "unprognostic (1.09e-1)" "potential prognostic unfavorable (1.81e-4)" "unprognostic (1.10e-2)" "unprognostic (5.05e-2)" "potential prognostic unfavorable (7.43e-4)" "unprognostic (1.10e-2)" "unprognostic (4.00e-1)" "unprognostic (1.85e-2)" "potential prognostic unfavorable (5.97e-4)" "unprognostic (3.29e-2)" "unprognostic (1.96e-1)" "unprognostic (4.87e-3)" "unprognostic (3.77e-1)" "unprognostic (4.75e-2)" "unprognostic (2.01e-1)" "unprognostic (3.45e-2)" "unprognostic (4.70e-2)" TNFRSF1B "CD120b, p75, TNF-R-II, TNF-R75, TNFBR, TNFR2, TNFR80" ENSG00000028137 "TNF receptor superfamily member 1B" P20333 1 12166991-12209228 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" Apoptosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 64.5" "Cell type enhanced" "Detected in many" "cDC: 285.4;Hofbauer cells: 137.6;Kupffer cells: 224.5;Macrophages: 321.3;monocytes: 897.7;Neutrophils: 1140.2;NK-cells: 219.0;T-cells: 186.6" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 150.7;endothelial cell: 76.7;leukocyte: 246.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 387.7" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 29.3" "Adrenal gland - Macrophages, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Liver - Neutrophils, Skeletal muscle - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA004796 Approved "Secreted to blood" Receptor NA NA 3230000 4100000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 55: Lymphoma - Immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 21 "HPA004796: " "unprognostic (1.97e-2)" "unprognostic (2.79e-2)" "unprognostic (3.84e-3)" "unprognostic (1.94e-2)" "unprognostic (2.34e-3)" "unprognostic (3.25e-2)" "unprognostic (1.78e-1)" "unprognostic (2.90e-1)" "unprognostic (2.25e-3)" "unprognostic (2.81e-1)" "potential prognostic favorable (1.36e-5)" "unprognostic (5.14e-2)" "unprognostic (2.38e-1)" "unprognostic (7.70e-2)" "unprognostic (9.59e-2)" "unprognostic (4.79e-2)" "unprognostic (5.96e-2)" "unprognostic (7.85e-3)" "unprognostic (1.86e-1)" "unprognostic (1.36e-3)" "unprognostic (1.78e-1)" "unprognostic (3.27e-1)" "unprognostic (1.75e-2)" "unprognostic (1.66e-1)" "unprognostic (3.46e-2)" "unprognostic (2.72e-2)" "unprognostic (8.84e-3)" "unprognostic (2.45e-1)" "unprognostic (1.22e-3)" "unprognostic (2.64e-1)" "unprognostic (9.56e-2)" TNFRSF21 "CD358, DR6" ENSG00000146072 "TNF receptor superfamily member 21" O75509 6 47231532-47309905 "CD markers, Plasma proteins, Predicted membrane proteins" "Adaptive immunity, Apoptosis, Host-virus interaction, Immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 108.8;urinary bladder: 138.2" "Cell type enhanced" "Detected in many" "Kupffer cells: 236.8;Ocular epithelial cells: 323.3;Papillary tip epithelial cells: 358.7;Prostatic club cells: 338.6;Syncytiotrophoblasts: 274.7;Urothelial cells: 982.2" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 280.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 35 "plasmacytoid DC: 69.3" "Lineage enriched" "Detected in single" 302 "dendritic cells: 69.3" "Low cancer specificity" "Detected in many" "Prostate - Urothelial cells, Spleen - Macrophages, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006746, CAB009805" Approved Supported "Plasma membrane,Cytosol" NA NA 350000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 69: Urothelial cells - Basic cellular functions" 4 "Plasma membrane, Cytosol" "CAB009805: , HPA006746: " "unprognostic (1.06e-1)" "unprognostic (7.93e-3)" "unprognostic (3.92e-1)" "unprognostic (5.90e-2)" "unprognostic (1.04e-1)" "unprognostic (1.22e-1)" "unprognostic (2.89e-1)" "unprognostic (6.99e-2)" "unprognostic (7.14e-2)" "unprognostic (1.92e-2)" "potential prognostic favorable (1.79e-7)" "unprognostic (4.11e-2)" "unprognostic (7.09e-2)" "unprognostic (1.33e-2)" "unprognostic (1.16e-2)" "unprognostic (8.33e-2)" "unprognostic (2.84e-2)" "unprognostic (2.55e-1)" "unprognostic (2.88e-2)" "unprognostic (2.58e-1)" "potential prognostic unfavorable (1.66e-4)" "unprognostic (2.27e-3)" "unprognostic (1.16e-1)" "unprognostic (1.83e-1)" "unprognostic (3.52e-1)" "unprognostic (1.98e-1)" "unprognostic (2.48e-2)" "unprognostic (5.00e-2)" "unprognostic (2.47e-1)" "unprognostic (1.96e-1)" "unprognostic (2.04e-2)" TNFRSF25 "APO-3, DDR3, DR3, LARD, TNFRSF12, TR3, TRAMP, WSL-1, WSL-LR" ENSG00000215788 "TNF receptor superfamily member 25" Q93038 1 6460786-6466175 "Predicted membrane proteins, Predicted secreted proteins" Apoptosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 42.2;lymphoid tissue: 39.8;pituitary gland: 26.7" "Cell type enhanced" "Detected in many" "Adipocytes: 36.7;Brain excitatory neurons: 59.1;Corticotrophs: 74.1;Innate lymphoid cells: 131.8;Thyrotrophs: 34.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "MAIT T-cell: 5.6;memory CD4 T-cell: 4.4;memory CD8 T-cell: 2.2;naive CD4 T-cell: 4.4;T-reg: 7.9" "Lineage enriched" "Detected in many" 7 "T-cells: 7.9" "Low cancer specificity" "Detected in many" "Breast - T-cells, Pituitary gland - Corticotropes, Skeletal muscle - Fibroblasts" "Group enriched" "Detected in some" 6 "amygdala: 1.2;cerebral cortex: 1.4;hippocampal formation: 2.0" "Low region specificity" "Detected in many" HPA069834 Approved "Nucleoplasm,Plasma membrane,Actin filaments,Focal adhesion sites" "Secreted - unknown location" Receptor NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 64: Non-specific - Transcription" "Cluster 35: Non-specific - DNA binding" "Cluster 24: Non-specific - Unknown function" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 3 "Plasma membrane, Actin filaments, Focal adhesion sites" Nucleoplasm "HPA069834: " "unprognostic (2.60e-2)" "unprognostic (2.51e-1)" "unprognostic (1.12e-1)" "unprognostic (4.06e-2)" "unprognostic (2.94e-2)" "unprognostic (2.43e-1)" "unprognostic (1.43e-2)" "unprognostic (3.42e-1)" "unprognostic (5.92e-2)" "unprognostic (2.30e-1)" "unprognostic (2.08e-1)" "unprognostic (1.31e-1)" "unprognostic (1.67e-1)" "unprognostic (1.00e-1)" "unprognostic (9.46e-2)" "unprognostic (1.42e-1)" "unprognostic (5.44e-2)" "unprognostic (1.40e-1)" "unprognostic (6.51e-3)" "unprognostic (2.71e-1)" "potential prognostic unfavorable (8.83e-4)" "unprognostic (8.79e-2)" "unprognostic (5.86e-2)" "unprognostic (3.87e-2)" "unprognostic (5.49e-2)" "unprognostic (1.61e-1)" "unprognostic (1.43e-1)" TNFRSF4 "ACT35, CD134, OX40, TXGP1L" ENSG00000186827 "TNF receptor superfamily member 4" P43489 1 1211326-1214153 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 9.6;heart muscle: 10.4;lymphoid tissue: 12.7" "Cell type enhanced" "Detected in some" "cDC: 41.2;Innate lymphoid cells: 126.9;Lymphatic endothelial cells: 23.6;Macrophages: 15.3;Mast cells: 49.6;Megakaryocytes: 18.5;NK-cells: 20.0;Plasma cells: 86.0;T-cells: 34.5;Thymocytes: 31.3;Vascular endothelial cells: 27.1" "Cell type enhanced" "Detected in some" "endothelial cell: 5.1;leukocyte: 5.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "memory CD4 T-cell: 25.6;T-reg: 31.0" "Lineage enriched" "Detected in many" 6 "T-cells: 31.0" "Group enriched" "Detected in some" 17 "Leukemia: 3.4;lymphoma: 10.7;thyroid cancer: 10.2" "Minor Salivary Gland - Plasma cells" "Low region specificity" "Detected in some" "Not detected" "Not detected" CAB016128 Enhanced NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 5: Spleen - Immune response" "Cluster 15: Non-specific - Transcription" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" 3 "CAB016128: " "unprognostic (3.49e-1)" "unprognostic (6.73e-2)" "unprognostic (6.05e-2)" "unprognostic (1.29e-3)" "unprognostic (1.48e-1)" "unprognostic (2.92e-1)" "unprognostic (3.37e-1)" "potential prognostic favorable (2.18e-6)" "unprognostic (3.35e-1)" "unprognostic (5.06e-2)" "unprognostic (2.58e-2)" "unprognostic (1.27e-2)" "potential prognostic unfavorable (3.99e-4)" "unprognostic (2.45e-1)" "unprognostic (2.34e-1)" "unprognostic (1.38e-1)" "unprognostic (2.50e-2)" "unprognostic (6.67e-2)" "unprognostic (4.31e-3)" "unprognostic (1.46e-1)" "unprognostic (7.79e-3)" "unprognostic (2.40e-2)" "unprognostic (2.84e-2)" "unprognostic (1.99e-1)" "unprognostic (2.01e-2)" "unprognostic (1.16e-1)" "unprognostic (2.15e-1)" "unprognostic (1.87e-1)" "unprognostic (4.48e-2)" "unprognostic (1.45e-1)" TNFRSF6B "DcR3, M68, TR6" ENSG00000243509 "TNF receptor superfamily member 6b" O95407 20 63696652-63698684 "Predicted secreted proteins" Apoptosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 53.3" "Cell type enhanced" "Detected in some" "Astrocytes: 8.5;Bergmann glia: 4.8;Brain excitatory neurons: 8.2;Brain inhibitory neurons: 10.7;Ependymal cells: 4.5;Microglia: 1.7;Oligodendrocyte progenitor cells: 4.8;Oligodendrocytes: 4.9;Other brain neurons: 7.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 16 "plasmacytoid DC: 21.6" "Lineage enriched" "Detected in many" 16 "dendritic cells: 21.6" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 144.8;pancreatic cancer: 170.2" HPA047154 Approved "Secreted to blood" Receptor NA NA 406000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 5: Spleen - Immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 104: Brain endothelial cells - Blood brain barrier" 25 "HPA047154: " "unprognostic (8.33e-3)" "unprognostic (3.16e-3)" "unprognostic (7.13e-2)" "unprognostic (1.99e-2)" "unprognostic (2.15e-1)" "unprognostic (1.85e-1)" "unprognostic (8.46e-3)" "unprognostic (9.70e-3)" "potential prognostic unfavorable (1.86e-5)" "unprognostic (4.25e-3)" "unprognostic (7.32e-2)" "unprognostic (2.77e-1)" "unprognostic (1.61e-2)" "unprognostic (1.12e-3)" "unprognostic (4.07e-1)" "unprognostic (1.25e-1)" "unprognostic (5.35e-2)" "unprognostic (5.95e-2)" "unprognostic (3.40e-2)" "unprognostic (3.31e-3)" "unprognostic (2.84e-2)" "unprognostic (1.72e-1)" "unprognostic (8.04e-2)" "unprognostic (1.50e-1)" "unprognostic (2.90e-2)" "unprognostic (3.75e-2)" "unprognostic (2.50e-1)" "unprognostic (3.64e-3)" "unprognostic (7.22e-2)" TNFRSF8 "CD30, D1S166E, KI-1" ENSG00000120949 "TNF receptor superfamily member 8" P28908 1 12063303-12144207 "Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 5.1" "Cell type enhanced" "Detected in many" "Epicardial cells: 100.1;Late spermatids: 13.4;Mast cells: 13.9;Mesothelial cells: 36.3;monocytes: 16.8;Neutrophils: 20.2;Podocytes: 12.9" "Cell type enhanced" "Detected in some" "leukocyte: 6.9;medium spiny neuron: 5.9" "Cancer enriched" "Detected in some" 10 "Testicular Germ Cell Tumor (TCGA): 11.6" "Group enriched" "Detected in some" 4 "basal ganglia: 4.8;thalamus: 1.5" "Group enriched" "Detected in many" 4 "intermediate monocyte: 59.4;non-classical monocyte: 97.0" "Lineage enriched" "Detected in many" 5 "monocytes: 97.0" "Cancer enriched" "Detected in some" 7 "lymphoma: 49.3" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Minor Salivary Gland - Endothelial cells" "Region enhanced" "Detected in many" "hypothalamus: 5.5" "Low region specificity" "Detected in all" "CAB000016, HPA014823, HPA032081, HPA032082" Approved Supported "Plasma membrane" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 33: Neurons - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 6 "Plasma membrane" "CAB000016: , HPA014823: , HPA032081: , HPA032082: " "potential prognostic favorable (9.62e-4)" "unprognostic (1.65e-2)" "unprognostic (6.89e-2)" TNFRSF9 "4-1BB, CD137, ILA" ENSG00000049249 "TNF receptor superfamily member 9" Q07011 1 7915871-7943165 "Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 9.2" "Cell type enhanced" "Detected in some" "cDC: 14.0;Epicardial cells: 9.1;Innate lymphoid cells: 19.1;Mast cells: 89.6;Neutrophils: 12.1;NK-cells: 26.3;T-cells: 44.5" "Cell type enriched" "Detected in single" 10 "leukocyte: 7.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "memory CD8 T-cell: 9.4;neutrophil: 8.6;NK-cell: 5.1;T-reg: 18.6" "Group enriched" "Detected in many" 5 "granulocytes: 8.6;NK-cells: 5.1;T-cells: 18.6" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA071425 Approved "Nucleoli,Plasma membrane" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 9: T-cells - Adaptive immunity: Regulation" 17 "Plasma membrane" Nucleoli "HPA071425: " "unprognostic (5.30e-3)" "unprognostic (1.75e-1)" "unprognostic (8.66e-2)" "unprognostic (2.14e-1)" "unprognostic (1.27e-1)" "unprognostic (2.31e-2)" "unprognostic (3.89e-3)" "unprognostic (2.50e-2)" "unprognostic (6.95e-3)" "unprognostic (4.28e-1)" "unprognostic (1.20e-2)" "unprognostic (3.32e-1)" "unprognostic (1.28e-2)" "unprognostic (1.03e-1)" "unprognostic (1.00e-1)" "unprognostic (8.82e-3)" "unprognostic (1.47e-3)" "unprognostic (1.76e-2)" "unprognostic (2.84e-2)" "unprognostic (3.98e-3)" "unprognostic (2.58e-1)" "unprognostic (6.10e-2)" "unprognostic (2.76e-2)" "unprognostic (1.00e-1)" TNFSF10 "Apo-2L, CD253, TL2, TRAIL" ENSG00000121858 "TNF superfamily member 10" P50591 3 172505508-172523475 "Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" Apoptosis Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 326.4;Esophageal apical cells: 805.4;Extravillous trophoblasts: 371.8;Neutrophils: 396.7;Prostatic club cells: 398.7;Prostatic hillock cells: 437.5;Respiratory deuterosomal cells: 322.4;Respiratory secretory cells: 400.1" "Cell type enriched" "Detected in some" 5 "endothelial cell: 285.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 266.3;classical monocyte: 133.5;intermediate monocyte: 203.5;neutrophil: 257.9;non-classical monocyte: 214.1" "Group enriched" "Detected in all" 5 "granulocytes: 266.3;monocytes: 214.1" "Group enriched" "Detected in many" 4 "head and neck cancer: 121.7;Kidney cancer: 166.1" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" HPA054938 Uncertain "Secreted to blood" Cytokine NA NA 67400 12000 "Cluster 28: Neutrophils - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 8: Immune cells - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 8 "HPA054938: " "unprognostic (8.83e-2)" "unprognostic (4.02e-2)" "unprognostic (3.71e-1)" "unprognostic (1.56e-1)" "unprognostic (2.15e-1)" "unprognostic (1.03e-1)" "unprognostic (2.43e-1)" "unprognostic (1.09e-1)" "unprognostic (2.32e-1)" "unprognostic (4.68e-3)" "unprognostic (1.31e-3)" "unprognostic (6.75e-2)" "unprognostic (1.93e-2)" "unprognostic (1.61e-1)" "unprognostic (5.34e-2)" "unprognostic (1.04e-1)" "unprognostic (4.36e-2)" "unprognostic (3.29e-2)" "unprognostic (2.58e-1)" "unprognostic (5.74e-2)" "unprognostic (1.29e-2)" "potential prognostic unfavorable (1.02e-4)" "unprognostic (2.45e-1)" "unprognostic (5.51e-2)" "unprognostic (2.06e-1)" "unprognostic (2.70e-2)" "unprognostic (9.49e-2)" "unprognostic (1.23e-1)" "unprognostic (4.01e-2)" "unprognostic (2.35e-2)" "unprognostic (1.95e-2)" TNFSF11 "CD254, ODF, OPGL, RANKL, TRANCE" ENSG00000120659 "TNF superfamily member 11" O14788 13 42562736-42608013 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Differentiation "Cytokine, Developmental protein, Receptor" "Cancer-related genes, Disease variant, FDA approved drug targets, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "liver: 3.9;lymphoid tissue: 11.5" "Cell type enriched" "Detected in some" 4 "Innate lymphoid cells: 146.8" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Pancreatic Adenocarcinoma (TCGA): 5.2" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in some" 8 "NK-cell: 9.9" "Lineage enriched" "Detected in many" 8 "NK-cells: 9.9" "Cancer enhanced" "Detected in some" "Rhabdoid: 1.5;thyroid cancer: 1.7" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "CAB009193, HPA045142" Enhanced "Secreted to blood" Cytokine NA NA 17200 "Cluster 15: NK-cells - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 44: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 4 "CAB009193: , HPA045142: " "unprognostic (4.49e-2)" "potential prognostic favorable (2.24e-4)" "unprognostic (1.22e-1)" "unprognostic (1.89e-1)" "unprognostic (2.71e-2)" "unprognostic (3.25e-2)" "unprognostic (1.53e-1)" "unprognostic (5.15e-2)" "unprognostic (4.62e-3)" "unprognostic (6.84e-2)" "unprognostic (8.06e-2)" "unprognostic (3.41e-2)" "unprognostic (6.47e-3)" "unprognostic (6.85e-2)" "unprognostic (9.64e-2)" "unprognostic (1.93e-1)" "unprognostic (8.95e-2)" TNFSF12 "APO3L, DR3LG, TWEAK" ENSG00000239697 "TNF superfamily member 12" O43508 17 7548508-7557890 "Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Apoptosis, Differentiation" "Cytokine, Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 9.9;Bergmann glia: 21.9;Brain excitatory neurons: 12.2;Brain inhibitory neurons: 9.9;Cardiomyocytes: 4.5;Ependymal cells: 7.3;Microglia: 20.7;Oligodendrocyte progenitor cells: 14.3;Other brain neurons: 10.3;Pericytes: 5.0" "Cell type enhanced" "Detected in all" "pericyte: 81.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035984, HPA052967" Uncertain Approved Vesicles "Secreted to blood" Cytokine NA NA 853000 110000 "Cluster 33: Non-specific - ATP binding" "Cluster 74: Non-specific - Signal transduction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 22: Non-specific - Basic cellular functions" 6 Vesicles "HPA035984: , HPA052967: " "unprognostic (3.18e-2)" "unprognostic (7.78e-2)" "unprognostic (5.15e-1)" "unprognostic (3.53e-1)" "unprognostic (4.22e-2)" "unprognostic (1.72e-1)" "unprognostic (1.48e-3)" "potential prognostic unfavorable (2.26e-4)" "unprognostic (3.47e-2)" "unprognostic (4.92e-2)" "potential prognostic favorable (1.58e-4)" "unprognostic (2.68e-3)" "potential prognostic favorable (2.44e-4)" "unprognostic (3.76e-2)" "unprognostic (5.06e-3)" "unprognostic (1.51e-2)" "unprognostic (2.47e-1)" "unprognostic (2.15e-2)" "unprognostic (1.35e-1)" "unprognostic (1.25e-1)" "unprognostic (3.76e-2)" "unprognostic (3.88e-2)" "unprognostic (1.16e-1)" "unprognostic (1.37e-1)" "unprognostic (6.05e-2)" "unprognostic (4.86e-2)" "unprognostic (3.05e-1)" "unprognostic (3.65e-2)" "unprognostic (5.64e-3)" "unprognostic (2.19e-1)" "unprognostic (1.67e-1)" TNFSF12-TNFSF13 TWE-PRIL ENSG00000248871 "TNFSF12-TNFSF13 readthrough" 17 7549099-7561601 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "choroid plexus: 7.3" "Cell type enhanced" "Detected in single" "Gastric chief cells: 1.1" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 13.4" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "eosinophil: 7.1" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "HPA004863, HPA035984, HPA052967" Uncertain Approved Vesicles NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" Vesicles "HPA004863: , HPA035984: , HPA052967: " "unprognostic (2.29e-1)" "unprognostic (2.67e-2)" "unprognostic (1.19e-2)" "unprognostic (1.53e-3)" "unprognostic (7.36e-3)" "unprognostic (2.68e-1)" "unprognostic (2.79e-1)" "potential prognostic unfavorable (2.16e-4)" "unprognostic (7.15e-2)" "unprognostic (6.98e-2)" "unprognostic (4.59e-2)" "unprognostic (3.20e-1)" "unprognostic (2.38e-1)" "unprognostic (4.06e-1)" "unprognostic (6.61e-2)" "unprognostic (1.10e-1)" "unprognostic (1.41e-1)" "unprognostic (5.01e-3)" "unprognostic (1.02e-1)" "unprognostic (1.26e-1)" "unprognostic (5.03e-2)" "unprognostic (1.95e-1)" TNFSF13 "APRIL, CD256" ENSG00000161955 "TNF superfamily member 13" O75888 17 7558292-7561608 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Immunity Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 169.6" "Cell type enhanced" "Detected in some" "Astrocytes: 27.8;Bergmann glia: 7.9;Choroid plexus epithelial cells: 7.0;Ependymal cells: 5.8;Microglia: 12.1;monocytes: 3.5" "Cell type enhanced" "Detected in some" "astrocyte: 25.8;central nervous system macrophage: 18.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 384.4" "Group enriched" "Detected in all" 11 "dendritic cells: 249.2;granulocytes: 139.3;monocytes: 384.4" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Colon - Macrophages, Lung - Macrophages, Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004863 Uncertain "Secreted to blood" Cytokine NA NA 6770000 390000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 102: Non-specific - Mixed function" 1 "HPA004863: " "unprognostic (9.30e-3)" "unprognostic (5.99e-2)" "unprognostic (9.89e-2)" "unprognostic (7.55e-2)" "unprognostic (1.57e-1)" "unprognostic (1.83e-2)" "potential prognostic unfavorable (1.31e-4)" "unprognostic (8.44e-3)" "unprognostic (2.70e-1)" "unprognostic (3.32e-1)" "potential prognostic favorable (7.92e-6)" "unprognostic (2.09e-3)" "potential prognostic favorable (2.28e-7)" "unprognostic (4.80e-3)" "unprognostic (8.92e-2)" "unprognostic (5.74e-2)" "unprognostic (1.25e-1)" "unprognostic (1.53e-1)" "unprognostic (6.48e-2)" "unprognostic (7.39e-2)" "unprognostic (2.81e-1)" "unprognostic (6.23e-2)" "unprognostic (7.41e-2)" "unprognostic (4.52e-1)" "unprognostic (4.22e-1)" "unprognostic (2.03e-2)" "unprognostic (1.07e-1)" "unprognostic (1.81e-1)" "unprognostic (5.25e-2)" "unprognostic (3.40e-1)" "unprognostic (3.12e-2)" TNFSF13B "BAFF, BLYS, CD257, TALL-1, TALL1, THANK, TNFSF20" ENSG00000102524 "TNF superfamily member 13b" Q9Y275 13 108251240-108308484 "Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Immunity Cytokine "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 24.4" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 86.2;cDC: 218.9;Choroid plexus epithelial cells: 144.1;Kupffer cells: 188.6;Macrophages: 100.6;Monocyte progenitors: 201.8;monocytes: 257.5;Neutrophil progenitors: 133.3;Neutrophils: 419.5;pDCs: 101.0;Platelets: 93.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 509.3" "Group enriched" "Detected in all" 11 "dendritic cells: 207.0;granulocytes: 509.3;monocytes: 352.4" "Cancer enriched" "Detected in some" 10 "Leukemia: 21.6" "Breast - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB009188, HPA030526" Enhanced Supported "Vesicles,Plasma membrane,Focal adhesion sites" "Secreted to blood" Cytokine NA NA 393000 480000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 8: Immune cells - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 27 "Plasma membrane" "Vesicles, Focal adhesion sites" "CAB009188: , HPA030526: " "unprognostic (5.03e-3)" "unprognostic (1.57e-1)" "unprognostic (1.19e-1)" "unprognostic (1.57e-1)" "unprognostic (1.05e-1)" "unprognostic (1.04e-1)" "unprognostic (2.11e-2)" "unprognostic (2.12e-1)" "unprognostic (1.26e-1)" "unprognostic (5.72e-2)" "potential prognostic unfavorable (5.23e-4)" "unprognostic (1.28e-1)" "unprognostic (3.10e-2)" "unprognostic (9.44e-2)" "unprognostic (1.68e-2)" "unprognostic (9.78e-2)" "unprognostic (1.24e-1)" "unprognostic (1.10e-2)" "unprognostic (3.48e-1)" "unprognostic (1.31e-1)" "unprognostic (4.85e-2)" "unprognostic (2.99e-2)" "unprognostic (3.60e-1)" "unprognostic (1.62e-1)" "unprognostic (1.08e-1)" "unprognostic (5.58e-2)" "unprognostic (1.77e-1)" "unprognostic (1.12e-1)" "unprognostic (3.08e-2)" "unprognostic (3.62e-1)" "unprognostic (1.56e-2)" TNFSF14 "CD258, HVEM-L, LIGHT, LTg" ENSG00000125735 "TNF superfamily member 14" O43557 19 6661253-6670588 "CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "adipose tissue: 24.3;liver: 92.6" "Cell type enhanced" "Detected in some" "Endometrial secretory cells: 20.4;Epicardial cells: 54.6;Innate lymphoid cells: 40.7;Mesothelial cells: 67.5;monocytes: 29.8;Neutrophils: 155.5;NK-cells: 53.3;T-cells: 35.9" "Cell type enriched" "Detected in some" 24 "leukocyte: 28.9" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 7.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 199.9" "Group enriched" "Detected in all" 4 "granulocytes: 199.9;T-cells: 61.2" "Cancer enhanced" "Detected in some" "Leukemia: 2.6;lymphoma: 3.6" "Adipose visceral - Mesothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA012700 Uncertain Approved Vesicles "Secreted to blood" Cytokine NA NA 41000 "Cluster 21: Neutrophils - Unknown function" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 12: Non-specific - Vasculature" "Cluster 55: Lymphoma - Immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 55 Vesicles "HPA012700: " "unprognostic (3.58e-2)" "unprognostic (1.31e-2)" "unprognostic (3.93e-2)" "unprognostic (1.53e-2)" "potential prognostic unfavorable (5.53e-4)" "unprognostic (7.63e-3)" "potential prognostic unfavorable (8.76e-9)" "unprognostic (1.28e-2)" "unprognostic (1.71e-1)" "unprognostic (5.92e-2)" "potential prognostic favorable (4.00e-5)" "unprognostic (4.20e-1)" "unprognostic (2.66e-1)" "unprognostic (4.29e-2)" "unprognostic (2.76e-1)" "unprognostic (1.53e-1)" "unprognostic (1.13e-1)" "unprognostic (1.22e-1)" "unprognostic (2.60e-3)" "unprognostic (5.76e-2)" "unprognostic (8.89e-2)" "unprognostic (2.41e-1)" "unprognostic (3.17e-2)" TNFSF15 "MGC129934, MGC129935, TL1, TL1A, VEGI, VEGI192A" ENSG00000181634 "TNF superfamily member 15" O95150 9 114784652-114806039 "Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 8.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 30.6;Basal prostatic cells: 25.3;Colonocytes: 29.9;Endometrial ciliated cells: 23.4;Endometrial glandular cells: 65.9;Enterocytes: 23.2;Epididymal basal cells: 48.7;Paneth cells: 27.1;Prostatic club cells: 74.4;Prostatic hillock cells: 39.7;Urothelial cells: 27.6" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 2.6;MGE interneuron: 5.9;vascular associated smooth muscle cell: 2.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - T-cells, Minor Salivary Gland - Minor salivary glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA012948, HPA046522" Uncertain Approved "Nucleoplasm,Nuclear membrane,Cytosol" "Secreted to blood" Cytokine NA NA 1110000 "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 7: Liver cancer - Metabolism" "Cluster 51: Secretory epithelial cells - Mixed function" 2 "Nuclear membrane" "Nucleoplasm, Cytosol" "HPA012948: , HPA046522: " "unprognostic (1.34e-2)" "unprognostic (4.26e-1)" "unprognostic (9.13e-2)" "unprognostic (6.30e-2)" "unprognostic (5.13e-2)" "unprognostic (4.08e-2)" "unprognostic (1.74e-1)" "unprognostic (4.44e-2)" "unprognostic (2.12e-1)" "unprognostic (1.88e-3)" "unprognostic (5.49e-2)" "unprognostic (2.82e-1)" "unprognostic (9.83e-2)" "unprognostic (6.96e-2)" "unprognostic (4.26e-2)" "unprognostic (6.44e-2)" "unprognostic (2.15e-1)" "unprognostic (1.65e-1)" "unprognostic (6.04e-2)" "unprognostic (1.02e-1)" "unprognostic (3.37e-1)" "unprognostic (1.43e-2)" "unprognostic (1.90e-1)" "unprognostic (3.21e-2)" "unprognostic (1.73e-2)" "unprognostic (4.93e-3)" "unprognostic (5.11e-2)" TNFSF18 "AITRL, hGITRL, TL6" ENSG00000120337 "TNF superfamily member 18" Q9UNG2 1 173039202-173050941 "Predicted intracellular proteins" "Adaptive immunity, Immunity" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.3;gallbladder: 1.4;pancreas: 1.4" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 4.3;cDC: 7.4;Epididymal basal cells: 22.3;Esophageal apical cells: 16.9;Esophageal suprabasal cells: 10.7;Hofbauer cells: 32.0;Macrophages: 7.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 7.5" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 82: Dendritic cells - Antigen presentation" 16 "unprognostic (1.54e-1)" "unprognostic (9.30e-2)" "unprognostic (1.15e-1)" "unprognostic (1.14e-1)" "unprognostic (2.19e-2)" "unprognostic (1.44e-2)" "unprognostic (2.04e-1)" "unprognostic (3.88e-2)" TNFSF4 "CD252, gp34, OX-40L, TXGP1" ENSG00000117586 "TNF superfamily member 4" P23510 1 173183731-173207331 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins" Cytokine "Cancer-related genes, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 10 "Platelets: 441.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Brain cancer: 9.2" "Testis - Sertoli cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA059579 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 37: Neurons - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 47: Platelets - Hemostasis" 1 "Nucleoplasm, Vesicles" "HPA059579: " "unprognostic (1.79e-1)" "unprognostic (1.85e-2)" "unprognostic (8.41e-3)" "unprognostic (1.07e-2)" "unprognostic (5.44e-3)" "unprognostic (4.49e-2)" "unprognostic (4.40e-3)" "unprognostic (3.14e-2)" "unprognostic (1.23e-1)" "unprognostic (1.08e-2)" "unprognostic (1.67e-1)" "potential prognostic unfavorable (5.81e-4)" "potential prognostic unfavorable (9.31e-4)" "unprognostic (1.99e-1)" "unprognostic (7.86e-2)" "potential prognostic unfavorable (8.24e-4)" "unprognostic (1.96e-1)" "unprognostic (2.76e-1)" "unprognostic (4.07e-2)" "unprognostic (2.48e-3)" "unprognostic (1.36e-2)" "unprognostic (6.43e-2)" "unprognostic (1.11e-1)" "unprognostic (7.79e-2)" "potential prognostic favorable (2.10e-5)" "unprognostic (1.71e-1)" "unprognostic (1.14e-2)" "unprognostic (1.00e-1)" "unprognostic (1.12e-1)" "unprognostic (2.56e-1)" TNFSF8 "CD153, CD30LG" ENSG00000106952 "TNF superfamily member 8" P32971 9 114893343-114930595 "Cancer-related genes, CD markers, Predicted membrane proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.6;lymphoid tissue: 25.0" "Cell type enhanced" "Detected in some" "B-cells: 44.5;cDC: 42.5;Hofbauer cells: 27.5;Innate lymphoid cells: 51.3;Kupffer cells: 22.5;Macrophages: 44.1;Microglia: 35.3;monocytes: 64.7;Neutrophils: 79.3;NK-cells: 26.8;T-cells: 168.5;Thymocytes: 85.5" "Group enriched" "Detected in some" 50 "central nervous system macrophage: 50.5;leukocyte: 56.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 4 "lymphoma: 12.5;testis cancer: 21.5" "Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Minor Salivary Gland - Macrophages, Skeletal muscle - Macrophages, Testis - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 27: Breast cancer - Unknown function" "Cluster 9: T-cells - Adaptive immunity: Regulation" 82 "unprognostic (1.36e-1)" "unprognostic (3.91e-2)" "unprognostic (2.13e-1)" "unprognostic (1.94e-1)" "unprognostic (5.80e-2)" "unprognostic (3.78e-1)" "unprognostic (7.53e-3)" "unprognostic (2.70e-1)" "unprognostic (1.38e-1)" "unprognostic (3.62e-2)" "unprognostic (1.25e-3)" "unprognostic (7.12e-2)" "unprognostic (1.22e-2)" "unprognostic (8.12e-2)" "unprognostic (2.62e-1)" "unprognostic (4.38e-2)" "unprognostic (1.86e-1)" "unprognostic (2.26e-1)" "unprognostic (5.72e-2)" "unprognostic (5.12e-2)" "unprognostic (4.79e-2)" "unprognostic (8.15e-2)" TNFSF9 "4-1BB-L, 4-1BBL, CD137L" ENSG00000125657 "TNF superfamily member 9" P41273 19 6531026-6535924 "Plasma proteins, Predicted intracellular proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 9.6;vagina: 9.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 38.2;B-cells: 34.6;cDC: 37.0;Endometrial secretory cells: 23.0;Epididymal basal cells: 69.8;Epididymal efferent duct absorptive cells: 21.7;Innate lymphoid cells: 20.6;pDCs: 60.7;T-cells: 30.8;Tuft cells: 23.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 48.8" "Adipose subcutaneous - Adipose progenitor cells, Spleen - B-cells (Spleen), Stomach - Fibroblasts" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA059857 Approved "Golgi apparatus" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 34: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 20: Non-specific - Transcription regulation" 38 "Golgi apparatus" "HPA059857: " "unprognostic (9.21e-2)" "unprognostic (1.78e-1)" "unprognostic (1.62e-1)" "unprognostic (1.45e-1)" "unprognostic (8.65e-2)" "unprognostic (4.04e-1)" "unprognostic (3.37e-2)" "unprognostic (3.45e-2)" "unprognostic (1.21e-1)" "unprognostic (7.08e-2)" "unprognostic (1.84e-1)" "unprognostic (6.08e-3)" "unprognostic (3.58e-2)" "unprognostic (3.49e-2)" "unprognostic (1.00e-1)" "unprognostic (1.22e-1)" "unprognostic (4.44e-2)" "unprognostic (7.58e-2)" "potential prognostic unfavorable (6.91e-4)" "unprognostic (3.84e-2)" "unprognostic (1.34e-2)" "unprognostic (4.72e-2)" "unprognostic (2.26e-1)" "unprognostic (7.40e-2)" "unprognostic (2.34e-1)" "unprognostic (1.08e-1)" "unprognostic (2.66e-1)" TNIK KIAA0551 ENSG00000154310 "TRAF2 and NCK interacting kinase" Q9UKE5 3 171058414-171460408 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Neurogenesis, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 2107.1;Bergmann glia: 1728.5;Ependymal cells: 1069.8;Mast cells: 1227.3;Myonuclei: 868.4;Pituicytes/FSCs: 1159.5;Pituitary stem cells: 1123.6;Sertoli cells: 1052.7" "Cell type enhanced" "Detected in all" "astrocyte: 2303.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Pituitary gland - Undifferentiated cells (Pituitary gland), Skin - Outer root sheath cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012128, HPA012297" Approved Supported Nucleoplasm,Cytosol NA NA 89000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 33: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 58: Mast cells - Allergic inflammatory responses" 51 Nucleoplasm Cytosol "HPA012128: , HPA012297: " "unprognostic (2.91e-1)" "unprognostic (1.36e-1)" "unprognostic (7.22e-3)" "unprognostic (7.24e-2)" "unprognostic (8.83e-2)" "unprognostic (1.11e-2)" "unprognostic (5.60e-2)" "unprognostic (1.17e-1)" "unprognostic (5.38e-2)" "unprognostic (1.14e-1)" "potential prognostic favorable (4.80e-4)" "unprognostic (2.04e-1)" "unprognostic (2.01e-1)" "unprognostic (1.01e-1)" "unprognostic (1.54e-1)" "unprognostic (2.49e-3)" "unprognostic (1.65e-1)" "unprognostic (1.18e-1)" "unprognostic (3.27e-1)" "unprognostic (7.78e-2)" "unprognostic (3.61e-1)" "unprognostic (5.35e-2)" "unprognostic (4.72e-2)" "unprognostic (6.52e-2)" "unprognostic (2.30e-1)" "unprognostic (1.32e-2)" "unprognostic (2.21e-1)" "unprognostic (2.96e-1)" "unprognostic (1.39e-1)" "unprognostic (1.15e-1)" "unprognostic (1.14e-3)" TNIP1 "ABIN-1, KIAA0113, NAF1, VAN" ENSG00000145901 "TNFAIP3 interacting protein 1" Q15025 5 151029945-151093577 "Human disease related genes, Predicted intracellular proteins" "Inflammatory response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 329.9;Esophageal apical cells: 665.8;Neutrophils: 716.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037893, HPA037894, HPA071950" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 47: Endothelial cells - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 167 Nucleoplasm Cytosol "HPA037893: , HPA037894: , HPA071950: " "unprognostic (5.42e-2)" "potential prognostic favorable (6.41e-4)" "unprognostic (7.39e-2)" "potential prognostic unfavorable (5.59e-4)" "unprognostic (6.65e-2)" "unprognostic (1.44e-1)" "unprognostic (5.70e-3)" "unprognostic (1.49e-1)" "unprognostic (2.04e-1)" "unprognostic (1.28e-1)" "validated prognostic favorable (1.04e-8)" "validated prognostic favorable (9.97e-4)" "unprognostic (8.97e-2)" "potential prognostic unfavorable (6.19e-4)" "unprognostic (4.77e-2)" "unprognostic (1.56e-2)" "unprognostic (6.76e-3)" "unprognostic (5.08e-3)" "unprognostic (8.29e-2)" "unprognostic (2.63e-2)" "unprognostic (2.16e-2)" "unprognostic (3.84e-2)" "unprognostic (1.96e-2)" "unprognostic (1.41e-1)" "unprognostic (5.84e-2)" "unprognostic (1.07e-1)" "unprognostic (2.20e-1)" "unprognostic (2.89e-1)" "unprognostic (8.67e-2)" "unprognostic (3.15e-2)" "unprognostic (2.85e-2)" TNIP2 "ABIN-2, FLIP1, KLIP, MGC4289" ENSG00000168884 "TNFAIP3 interacting protein 2" Q8NFZ5 4 2741648-2756342 "Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Inflammatory response, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 158.9;Extravillous trophoblasts: 138.2;Syncytiotrophoblasts: 120.3" "Cell type enhanced" "Detected in many" "pericyte: 23.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020818, HPA049886, HPA063197" Supported Enhanced Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 72 Nucleoplasm Cytosol "CAB020818: , HPA049886: , HPA063197: " "unprognostic (1.94e-1)" "unprognostic (2.31e-1)" "unprognostic (8.76e-3)" "unprognostic (1.95e-1)" "unprognostic (2.31e-1)" "unprognostic (2.66e-2)" "unprognostic (2.73e-1)" "potential prognostic favorable (5.39e-5)" "unprognostic (1.96e-1)" "unprognostic (3.59e-1)" "unprognostic (1.08e-3)" "unprognostic (1.73e-1)" "unprognostic (2.70e-1)" "unprognostic (2.07e-3)" "potential prognostic unfavorable (1.90e-4)" "unprognostic (1.18e-2)" "potential prognostic unfavorable (1.64e-5)" "unprognostic (1.95e-3)" "unprognostic (9.92e-2)" "unprognostic (1.08e-2)" "unprognostic (3.34e-3)" "unprognostic (9.51e-2)" "unprognostic (1.07e-2)" "unprognostic (1.62e-1)" "unprognostic (1.14e-1)" "unprognostic (2.53e-2)" "unprognostic (5.06e-1)" "unprognostic (2.16e-1)" "unprognostic (2.38e-1)" "unprognostic (6.61e-2)" "unprognostic (3.53e-2)" TNIP3 "ABIN-3, FLJ21162, LIND" ENSG00000050730 "TNFAIP3 interacting protein 3" Q96KP6 4 121131408-121227466 "Predicted intracellular proteins" "Inflammatory response" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 6.0;urinary bladder: 3.9" "Cell type enhanced" "Detected in some" "Early spermatids: 23.9;Endometrial secretory cells: 45.7;Late spermatids: 92.0;Macrophages: 23.6;monocytes: 199.8;NK-cells: 19.4;T-cells: 106.3" "Cell type enriched" "Detected in some" 4 "leukocyte: 44.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory CD8 T-cell: 6.2" "Lineage enriched" "Detected in single" 10 "T-cells: 6.2" "Cancer enhanced" "Detected in many" "lymphoma: 5.9" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA043063 Uncertain Approved "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 31 "Nucleoplasm, Cytosol" "Nuclear bodies, Plasma membrane" "HPA043063: " "unprognostic (1.65e-1)" "unprognostic (1.53e-1)" "unprognostic (1.70e-1)" "unprognostic (3.16e-2)" "unprognostic (2.83e-2)" "unprognostic (9.62e-3)" "unprognostic (1.68e-3)" "unprognostic (1.17e-1)" "unprognostic (1.31e-1)" "unprognostic (2.41e-2)" "unprognostic (4.16e-2)" "unprognostic (2.66e-1)" "unprognostic (1.95e-2)" "unprognostic (1.59e-1)" "unprognostic (3.69e-2)" "unprognostic (9.68e-3)" "unprognostic (1.38e-1)" TNK1 KOS1 ENSG00000174292 "Tyrosine kinase non receptor 1" Q13470 17 7380534-7389774 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 2.4;Brain inhibitory neurons: 2.9;Choroid plexus epithelial cells: 1.6;Distal convoluted tubule cells: 2.1;Loop of henle epithelial cells: 2.9;Papillary tip epithelial cells: 3.1;Podocytes: 1.3;Proximal tubule cells: 2.0;Renal collecting duct intercalated cells: 1.7;Renal collecting duct principal cells: 3.0;Renal connecting tubule cells: 1.5" "Cell type enhanced" "Detected in some" "medium spiny neuron: 6.8;upper rhombic lip: 4.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "B-cells: 1.0;T-cells: 2.6" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Spleen - B-cells (Spleen)" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA012065, HPA056452" Uncertain Approved "Cell Junctions" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 60: Stomach - Digestion" "Cluster 15: Non-specific - Transcription" "Cluster 42: Non-specific - Unknown function" "Cluster 102: Non-specific - Mixed function" 12 "Cell Junctions" "HPA012065: , HPA056452: " "unprognostic (4.34e-3)" "unprognostic (6.79e-3)" "unprognostic (2.33e-1)" "unprognostic (1.69e-3)" "unprognostic (1.36e-1)" "potential prognostic favorable (5.63e-5)" "unprognostic (1.08e-1)" "unprognostic (2.38e-1)" "potential prognostic favorable (6.77e-7)" "unprognostic (3.96e-2)" "unprognostic (8.27e-3)" "unprognostic (2.11e-2)" "unprognostic (1.67e-1)" "unprognostic (7.58e-2)" "unprognostic (9.11e-2)" "unprognostic (1.60e-1)" "unprognostic (3.06e-1)" "unprognostic (1.13e-2)" "unprognostic (1.17e-1)" "unprognostic (1.61e-1)" "unprognostic (1.06e-1)" "unprognostic (5.03e-1)" "unprognostic (3.00e-2)" "unprognostic (3.25e-2)" "unprognostic (1.36e-1)" "unprognostic (4.08e-3)" "unprognostic (1.52e-1)" "unprognostic (1.47e-1)" "unprognostic (1.08e-1)" TNK2 "ACK, ACK1, p21cdc42Hs" ENSG00000061938 "Tyrosine kinase non receptor 2" Q07912 3 195863364-195911945 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" Endocytosis "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 115.0;Oligodendrocyte progenitor cells: 391.1" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 301.5;oligodendrocyte precursor cell: 409.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Colon - Enteric glia cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041954, HPA069561" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 78: Brain - Neuronal signaling" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 56 "Plasma membrane" Vesicles "HPA041954: , HPA069561: " "unprognostic (1.69e-1)" "unprognostic (4.78e-2)" "unprognostic (1.98e-1)" "unprognostic (2.05e-1)" "potential prognostic unfavorable (5.66e-4)" "unprognostic (2.54e-2)" "unprognostic (1.20e-1)" "potential prognostic favorable (9.49e-4)" "unprognostic (1.25e-1)" "unprognostic (2.30e-1)" "unprognostic (1.59e-2)" "unprognostic (1.71e-1)" "unprognostic (2.08e-1)" "unprognostic (1.38e-1)" "unprognostic (3.86e-2)" "unprognostic (2.85e-1)" "unprognostic (1.10e-2)" "unprognostic (1.39e-1)" "unprognostic (2.54e-2)" "unprognostic (5.68e-2)" "unprognostic (2.62e-2)" "unprognostic (2.74e-3)" "unprognostic (1.19e-2)" "unprognostic (1.02e-1)" "unprognostic (2.52e-1)" "unprognostic (2.04e-1)" "unprognostic (2.81e-2)" "unprognostic (1.16e-1)" "unprognostic (3.92e-1)" "unprognostic (1.53e-1)" "unprognostic (1.61e-1)" TNKS "ARTD5, PARP-5a, PARP5A, pART5, TIN1, TINF1, TNKS1" ENSG00000173273 Tankyrase O95271 8 9555912-9782346 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis, mRNA transport, Protein transport, Translocation, Transport, Wnt signaling pathway" "Glycosyltransferase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 228.6;Bergmann glia: 255.4;Brain excitatory neurons: 290.2;Brain inhibitory neurons: 351.3;Choroid plexus epithelial cells: 303.1;Distal convoluted tubule cells: 256.8;Ependymal cells: 311.1;Loop of henle epithelial cells: 209.0;Microglia: 187.7;Oligodendrocyte progenitor cells: 525.9;Oligodendrocytes: 389.3;Other brain neurons: 297.9;Podocytes: 326.5;Proximal tubule cells: 213.0;Renal collecting duct intercalated cells: 219.0;Renal collecting duct principal cells: 192.7;Renal connecting tubule cells: 257.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025690 Approved Approved "Nucleoplasm,Nuclear membrane,Nuclear bodies" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 102: Non-specific - Mixed function" 50 Nucleoplasm "Nuclear membrane, Nuclear bodies" "HPA025690: " "unprognostic (6.70e-2)" "unprognostic (3.87e-2)" "unprognostic (2.35e-2)" "unprognostic (5.34e-2)" "unprognostic (1.93e-2)" "unprognostic (1.71e-1)" "unprognostic (3.00e-1)" "unprognostic (1.68e-2)" "unprognostic (5.75e-3)" "unprognostic (6.20e-3)" "potential prognostic favorable (3.64e-4)" "unprognostic (1.85e-3)" "unprognostic (3.85e-2)" "unprognostic (1.35e-2)" "unprognostic (4.51e-2)" "unprognostic (3.10e-2)" "unprognostic (9.18e-2)" "unprognostic (1.56e-1)" "unprognostic (1.39e-1)" "unprognostic (1.69e-2)" "unprognostic (1.15e-2)" "unprognostic (2.62e-1)" "unprognostic (5.70e-1)" "unprognostic (4.62e-2)" "unprognostic (1.71e-3)" "potential prognostic favorable (9.84e-5)" "unprognostic (7.97e-2)" "unprognostic (1.09e-1)" "unprognostic (2.82e-1)" "unprognostic (7.79e-3)" "unprognostic (7.63e-2)" TNKS1BP1 "FLJ45975, KIAA1741, TAB182" ENSG00000149115 "Tankyrase 1 binding protein 1" Q9C0C2 11 57299638-57324952 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epicardial cells: 118.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037929, HPA037930" Enhanced Approved "Plasma membrane" NA NA 13000 "Cluster 11: Esophagus - Basic cellular processes" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 26: Keratinocytes - Keratinization" 44 "Plasma membrane" "HPA037929: , HPA037930: " "unprognostic (4.75e-2)" "unprognostic (1.62e-1)" "unprognostic (1.25e-1)" "potential prognostic unfavorable (6.85e-4)" "unprognostic (1.69e-1)" "unprognostic (7.37e-2)" "unprognostic (2.75e-1)" "unprognostic (1.41e-2)" "unprognostic (1.77e-1)" "unprognostic (6.56e-2)" "unprognostic (7.34e-3)" "unprognostic (1.05e-1)" "unprognostic (2.22e-2)" "unprognostic (3.52e-2)" "potential prognostic favorable (4.43e-4)" "unprognostic (1.26e-1)" "unprognostic (2.45e-2)" "unprognostic (3.68e-2)" "unprognostic (1.64e-2)" "unprognostic (4.32e-2)" "unprognostic (4.02e-1)" "unprognostic (1.17e-3)" "unprognostic (5.98e-3)" "unprognostic (2.94e-1)" "unprognostic (2.27e-2)" "unprognostic (6.55e-2)" "unprognostic (2.57e-1)" "unprognostic (1.43e-1)" "unprognostic (2.51e-1)" "unprognostic (7.41e-2)" "unprognostic (9.33e-2)" TNKS2 "ARTD6, PARP-5b, PARP-5c, PARP5B, PARP5C, pART6, TANK2, TNKL" ENSG00000107854 "Tankyrase 2" Q9H2K2 10 91798426-91865475 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Wnt signaling pathway" "Glycosyltransferase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 545.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036606 Approved Microtubules NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 41 Microtubules "HPA036606: " "unprognostic (2.60e-3)" "unprognostic (5.22e-2)" "unprognostic (6.10e-2)" "unprognostic (8.51e-2)" "unprognostic (1.21e-1)" "unprognostic (2.31e-2)" "unprognostic (8.74e-3)" "potential prognostic favorable (3.85e-4)" "unprognostic (1.39e-2)" "unprognostic (9.61e-2)" "potential prognostic favorable (3.25e-5)" "unprognostic (4.14e-3)" "unprognostic (7.95e-2)" "unprognostic (2.07e-1)" "unprognostic (1.83e-1)" "unprognostic (2.43e-1)" "unprognostic (9.37e-2)" "unprognostic (1.61e-1)" "unprognostic (3.94e-1)" "unprognostic (1.34e-2)" "unprognostic (2.51e-3)" "unprognostic (3.44e-3)" "unprognostic (6.33e-2)" "unprognostic (1.29e-2)" "unprognostic (6.78e-2)" "potential prognostic favorable (3.51e-4)" "unprognostic (2.28e-1)" "unprognostic (3.53e-1)" "unprognostic (3.46e-1)" "unprognostic (3.41e-2)" "unprognostic (3.87e-1)" TNMD "BRICD4, ChM1L, myodulin, TEM, tendin" ENSG00000000005 Tenomodulin Q9H2S6 X 100584936-100599885 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 22.3;breast: 14.2;seminal vesicle: 24.6" "Cell type enhanced" "Detected in some" "Adipocytes: 10.4;Fibro-adipogenic progenitors: 2.8;Fibroblasts: 3.0;Granulosa cells: 2.4;Hepatic stellate cells: 6.5;Leydig cells: 11.0;Ovarian stromal cells: 11.0;Retinal ganglion cells: 3.9;Vascular endothelial cells: 5.1" "Cell type enhanced" "Detected in single" "choroid plexus epithelial cell: 2.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "testis cancer: 1.1;Uterine cancer: 1.3" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA034961, HPA055634" Uncertain NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 36: Choroid plexus - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 94: Gonadal somatic cells - Mixed function" 1 "HPA034961: , HPA055634: " "unprognostic (2.09e-1)" "unprognostic (1.54e-1)" "unprognostic (6.13e-3)" "unprognostic (1.79e-3)" "unprognostic (4.58e-1)" "unprognostic (1.45e-3)" "unprognostic (2.32e-1)" "unprognostic (1.55e-1)" TNN TNW ENSG00000120332 "Tenascin N" Q9UQP3 1 175067833-175148075 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 11.3;breast: 4.6" "Cell type enhanced" "Detected in some" "Fibroblasts: 10.8;Late spermatids: 3.5;Mucous neck cells: 4.0;Pericytes: 14.7;Salivary acinar cells: 13.3;Schwann cells: 3.1" "Cell type enriched" "Detected in some" 10 "fibroblast: 22.0" "Cancer enhanced" "Detected in some" "Breast Invasive Carcinoma (TCGA): 3.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 1.2;Leukemia: 1.3;Myeloma: 1.6" "Liver - Hepatic stellate cells, Pituitary gland - Fibroblasts, Skin - Outer root sheath cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB010907, HPA026726, HPA026764" Uncertain "Secreted to extracellular matrix" "No annotated function" NA NA 13000000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 50: Lymphoma - Unknown function" "Cluster 108: Fibroblasts - ECM organization" "CAB010907: , HPA026726: , HPA026764: " "unprognostic (1.15e-1)" "unprognostic (1.41e-3)" "unprognostic (4.24e-2)" "unprognostic (1.16e-2)" "unprognostic (1.93e-2)" TNNC1 TNNC ENSG00000114854 "Troponin C1, slow skeletal and cardiac type" P63316 3 52451100-52454041 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Muscle protein" "Cardiomyopathy, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 37 "heart muscle: 8750.1;skeletal muscle: 19761.9;tongue: 11563.6" "Cell type enriched" "Detected in many" 6 "Thymic myoid cells: 2553.4" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 4.8;fibroblast: 4.7" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 83.8" "Group enriched" "Detected in many" 6 "cerebellum: 5.0;choroid plexus: 15.5" "Immune cell enhanced" "Detected in single" "MAIT T-cell: 1.2" "Lineage enriched" "Detected in single" 6 "T-cells: 1.2" "Cancer enhanced" "Detected in many" "ovarian cancer: 94.2" "Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 1, Skeletal muscle - Skeletal myocytes, Skin - Keratinocyte (granular)" "Region enriched" "Detected in all" 4 "cerebral cortex: 87.0" "Group enriched" "Detected in some" 6 "midbrain: 10.1;spinal cord: 9.5" "CAB002450, HPA044848, HPA056897" Enhanced Approved "Nucleoplasm,Actin filaments,Mitochondria" NA NA 890000 "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 5: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 15 "Nucleoplasm, Actin filaments, Mitochondria" "CAB002450: , HPA044848: , HPA056897: " "unprognostic (1.57e-1)" "unprognostic (3.13e-2)" "unprognostic (5.59e-2)" "unprognostic (2.96e-2)" "unprognostic (1.82e-1)" "unprognostic (2.79e-2)" "unprognostic (9.76e-3)" "unprognostic (9.45e-2)" "unprognostic (1.95e-1)" "unprognostic (1.71e-2)" "unprognostic (2.23e-2)" "unprognostic (3.43e-2)" "unprognostic (2.38e-2)" "unprognostic (5.19e-2)" "unprognostic (1.90e-2)" "unprognostic (1.21e-1)" "unprognostic (3.98e-1)" "unprognostic (5.39e-2)" "unprognostic (1.33e-1)" "unprognostic (1.11e-1)" "unprognostic (7.04e-2)" "unprognostic (4.71e-2)" "unprognostic (1.15e-3)" "unprognostic (5.91e-2)" "unprognostic (2.37e-1)" "unprognostic (3.42e-2)" "unprognostic (2.56e-1)" TNNC2 "CFAP85, FAP85" ENSG00000101470 "Troponin C2, fast skeletal type" P02585 20 45823214-45833745 "Human disease related genes, Predicted intracellular proteins" "Muscle protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 102 "skeletal muscle: 28518.2;tongue: 7540.4" "Cell type enriched" "Detected in many" 7 "Thymic myoid cells: 2523.5" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Colon Adenocarcinoma (TCGA): 37.3;Head and Neck Squamous Cell Carcinoma (TCGA): 51.2;Lung Adenocarcinoma (TCGA): 25.6;Rectum Adenocarcinoma (TCGA): 57.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 5 "colorectal cancer: 6.6;Sarcoma: 21.5" "Skeletal muscle - Skeletal myocytes" "Region enriched" "Detected in some" 5 "olfactory bulb: 6.1" "Low region specificity" "Detected in some" "HPA043174, HPA058481" Enhanced Approved Nucleoplasm,Vesicles No NA 780000 "Cluster 7: Non-specific - Innate immune response" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 53: Neurons - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 13 Nucleoplasm Vesicles "HPA043174: , HPA058481: " "unprognostic (1.62e-1)" "unprognostic (8.69e-2)" "unprognostic (2.24e-2)" "unprognostic (1.36e-2)" "unprognostic (1.17e-1)" "unprognostic (1.35e-1)" "potential prognostic unfavorable (6.62e-5)" "unprognostic (3.77e-1)" "unprognostic (1.33e-2)" "unprognostic (3.62e-2)" "potential prognostic favorable (9.13e-4)" "unprognostic (3.64e-2)" "unprognostic (2.75e-1)" "unprognostic (1.86e-1)" "unprognostic (3.29e-1)" "unprognostic (1.65e-1)" "unprognostic (8.81e-2)" "unprognostic (8.93e-2)" "unprognostic (2.11e-1)" "unprognostic (1.54e-1)" "unprognostic (2.12e-3)" "unprognostic (3.01e-1)" "unprognostic (1.66e-2)" "unprognostic (1.59e-1)" TNNI1 ENSG00000159173 "Troponin I1, slow skeletal type" P19237 1 201403768-201429866 "Predicted intracellular proteins" "Actin-binding, Muscle protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 40 "skeletal muscle: 11781.0;tongue: 2947.8" "Cell type enriched" "Detected in some" 10 "Myonuclei: 739.0" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "Head and Neck Squamous Cell Carcinoma (TCGA): 89.5;Prostate Adenocarcinoma (TCGA): 25.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 9 "Sarcoma: 171.9" "Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028190 Approved Uncertain Nucleoplasm,Nucleoli NA NA 340000 "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 55: Myocytes - Oxidative muscle function" 34 Nucleoplasm Nucleoli "HPA028190: " "unprognostic (4.05e-2)" "unprognostic (8.12e-2)" "unprognostic (2.58e-1)" "unprognostic (2.82e-2)" "unprognostic (9.56e-2)" "unprognostic (2.25e-1)" "unprognostic (1.24e-3)" "unprognostic (2.17e-1)" "unprognostic (1.11e-1)" "unprognostic (1.38e-3)" "unprognostic (1.44e-1)" "unprognostic (7.72e-2)" "unprognostic (3.38e-1)" "unprognostic (1.56e-2)" "unprognostic (2.88e-2)" "unprognostic (2.14e-1)" "unprognostic (9.08e-2)" "unprognostic (3.05e-2)" "unprognostic (1.04e-2)" "unprognostic (3.43e-1)" "unprognostic (1.25e-1)" "unprognostic (1.11e-1)" "unprognostic (7.10e-2)" "unprognostic (5.00e-2)" "unprognostic (2.03e-1)" TNNI2 "AMCD2B, DA2B, FSSV" ENSG00000130598 "Troponin I2, fast skeletal type" P48788 11 1838981-1841680 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin-binding, Muscle protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 24 "skeletal muscle: 7469.2;tongue: 2445.9" "Cell type enriched" "Detected in some" 9 "Thymic myoid cells: 4847.1" "Group enriched" "Detected in some" 10 "central nervous system macrophage: 3.3;leukocyte: 2.2" "Group enriched" "Detected in many" 10 "Bladder Urothelial Carcinoma (TCGA): 29.6;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 13.3;Head and Neck Squamous Cell Carcinoma (TCGA): 41.7;Pancreatic Adenocarcinoma (TCGA): 12.3" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 86.2" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Bladder cancer: 8.0" "Skeletal muscle - Skeletal myocytes" "Region enriched" "Detected in single" 6 "olfactory bulb: 5.1" "Low region specificity" "Detected in some" "CAB018697, HPA055938" Enhanced Approved "Plasma membrane,Intermediate filaments" NA NA 87000 "Cluster 29: Non-specific - Unknown function" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 59: Leukemia - T-cell receptor" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 13 "Plasma membrane" "Intermediate filaments" "CAB018697: , HPA055938: " "unprognostic (2.91e-2)" "unprognostic (3.91e-2)" "unprognostic (1.46e-2)" "unprognostic (1.26e-2)" "unprognostic (6.39e-3)" "unprognostic (2.10e-3)" "unprognostic (1.30e-1)" "unprognostic (4.62e-3)" "unprognostic (3.49e-2)" "unprognostic (1.18e-2)" "unprognostic (1.85e-1)" "unprognostic (2.22e-2)" "unprognostic (9.66e-2)" "unprognostic (4.20e-2)" "unprognostic (9.84e-2)" "potential prognostic unfavorable (4.21e-5)" "unprognostic (1.48e-1)" "unprognostic (1.14e-2)" "unprognostic (5.81e-2)" "unprognostic (1.28e-2)" TNNI3 "CMD2A, CMH7, TNNC1" ENSG00000129991 "Troponin I3, cardiac type" P19429 19 55151767-55157773 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Muscle protein" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 158 "heart muscle: 10359.2" "Group enriched" "Detected in some" 7 "Granulosa cells: 866.1;Late spermatids: 367.6" "Group enriched" "Detected in some" 4 "ependymal cell: 9.3;hippocampal CA4: 4.7" "Group enriched" "Detected in many" 5 "Testicular Germ Cell Tumor (TCGA): 20.5;Uterine Corpus Endometrial Carcinoma (TCGA): 11.2" "Region enhanced" "Detected in many" "midbrain: 5.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 8.1" "Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Skeletal muscle - Skeletal myocytes, Testis - Late spermatids" "Region enhanced" "Detected in many" "olfactory bulb: 10.9" "Low region specificity" "Detected in all" "CAB009349, HPA046428" Enhanced Approved Vesicles,Cytosol NA NA 81000 "Cluster 35: Non-specific - Mixed function" "Cluster 46: Brainstem - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 108: Fibroblasts - ECM organization" 18 Cytosol Vesicles "CAB009349: , HPA046428: " "unprognostic (1.09e-1)" "unprognostic (3.27e-1)" "unprognostic (1.27e-1)" "unprognostic (1.84e-1)" "unprognostic (3.08e-1)" "unprognostic (3.67e-2)" "unprognostic (2.08e-1)" "unprognostic (3.27e-2)" "unprognostic (2.12e-1)" "unprognostic (3.42e-2)" "unprognostic (1.64e-1)" "unprognostic (2.63e-1)" "unprognostic (2.73e-2)" "unprognostic (8.45e-2)" "unprognostic (2.63e-1)" TNNI3K CARK ENSG00000116783 "TNNI3 interacting kinase" Q59H18 1 74235387-74544428 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "heart muscle: 54.6" "Cell type enhanced" "Detected in some" "Astrocytes: 67.7;Bergmann glia: 85.1;Brain excitatory neurons: 56.5;Brain inhibitory neurons: 48.1;Ependymal cells: 126.6;Microglia: 25.8;Oligodendrocyte progenitor cells: 58.4;Oligodendrocytes: 78.6;Other brain neurons: 29.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 28: Astrocytes - Homeostasis & neuron support" 8 "unprognostic (3.08e-1)" "unprognostic (9.16e-2)" "unprognostic (1.40e-1)" TNNT1 "ANM, FLJ98147, MGC104241, NEM5, STNT, TNT, TNTS" ENSG00000105048 "Troponin T1, slow skeletal type" P13805 19 55132698-55149206 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Muscle protein" "Disease variant, Nemaline myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 29 "skeletal muscle: 20208.4;tongue: 12476.3" "Cell type enriched" "Detected in many" 5 "Myonuclei: 2183.9" "Cell type enhanced" "Detected in many" "astrocyte: 5.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "eosinophil: 212.2" "Lineage enriched" "Detected in many" 5 "granulocytes: 212.2" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Skeletal muscle - Skeletal myocytes, Skin - Keratinocyte (other)" "Region enriched" "Detected in many" 5 "thalamus: 125.0" "Region enhanced" "Detected in all" "thalamus: 35.8" "CAB015168, HPA058448" Enhanced Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 890000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 55: Myocytes - Oxidative muscle function" 16 "Nucleoplasm, Golgi apparatus, Cytosol" "CAB015168: , HPA058448: " "unprognostic (1.45e-2)" "unprognostic (2.68e-1)" "unprognostic (1.19e-1)" "unprognostic (2.04e-2)" "potential prognostic unfavorable (5.18e-4)" "unprognostic (2.87e-2)" "unprognostic (1.51e-3)" "unprognostic (5.12e-2)" "unprognostic (4.34e-3)" "unprognostic (2.87e-2)" "validated prognostic unfavorable (1.67e-15)" "validated prognostic unfavorable (2.21e-5)" "potential prognostic unfavorable (4.30e-4)" "potential prognostic unfavorable (3.68e-5)" "unprognostic (2.00e-2)" "potential prognostic unfavorable (5.42e-4)" "unprognostic (2.17e-1)" "unprognostic (3.56e-1)" "unprognostic (9.66e-2)" "unprognostic (1.09e-1)" "unprognostic (4.20e-2)" "validated prognostic unfavorable (3.89e-4)" "validated prognostic unfavorable (1.05e-5)" "unprognostic (1.44e-1)" "unprognostic (3.72e-2)" "unprognostic (1.33e-1)" "unprognostic (2.36e-1)" "unprognostic (3.15e-2)" "unprognostic (1.65e-1)" "unprognostic (2.19e-2)" "unprognostic (4.09e-2)" TNNT2 "CMD1D, CMH2, CMPD2" ENSG00000118194 "Troponin T2, cardiac type" P45379 1 201359008-201377764 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Muscle protein" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 153 "heart muscle: 8731.9" "Group enriched" "Detected in some" 14 "Cardiomyocytes: 198.7;Podocytes: 112.8" "Cell type enriched" "Detected in some" 7 "hippocampal dentate gyrus: 62.9" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 11.7" "Group enriched" "Detected in some" 7 "cerebral cortex: 17.9;hippocampal formation: 11.0;white matter: 8.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Rhabdoid: 30.1;Sarcoma: 110.6;testis cancer: 56.3" "Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Kidney - Podocytes" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebral cortex: 5.0" "CAB015371, HPA015774, HPA017888" Enhanced Uncertain "Nucleoplasm,Nucleoli,Focal adhesion sites,Microtubules" No No 72000 "Cluster 35: Non-specific - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 4 "Nucleoplasm, Nucleoli" "Focal adhesion sites, Microtubules" "CAB015371: , HPA015774: , HPA017888: " "unprognostic (1.79e-1)" "unprognostic (1.38e-1)" "unprognostic (3.84e-2)" "unprognostic (4.79e-3)" "unprognostic (1.01e-2)" "unprognostic (1.79e-1)" "unprognostic (4.33e-1)" "unprognostic (5.00e-2)" "unprognostic (1.97e-2)" "unprognostic (1.57e-2)" "unprognostic (1.41e-2)" "unprognostic (3.01e-2)" "unprognostic (2.21e-1)" "unprognostic (1.93e-1)" "unprognostic (6.70e-2)" "unprognostic (1.78e-1)" "unprognostic (3.17e-2)" TNNT3 "AMCD2B, DA2B, DKFZp779M2348, FSSV" ENSG00000130595 "Troponin T3, fast skeletal type" P45378 11 1919703-1938706 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Muscle protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 41 "skeletal muscle: 13033.0;tongue: 4206.7" "Cell type enriched" "Detected in some" 68 "Thymic myoid cells: 4499.0" "Cell type enriched" "Detected in single" 4 "leukocyte: 1.5" "Group enriched" "Detected in many" 8 "Bladder Urothelial Carcinoma (TCGA): 26.6;Head and Neck Squamous Cell Carcinoma (TCGA): 62.9" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 17 "basophil: 5.3" "Lineage enriched" "Detected in single" 17 "granulocytes: 5.3" "Group enriched" "Detected in some" 4 "Bladder cancer: 16.3;Rhabdoid: 16.5" "Skeletal muscle - Skeletal myocytes, Thyroid gland - Fibroblasts" "Region enhanced" "Detected in some" "olfactory bulb: 5.1" "Low region specificity" "Detected in many" "CAB002451, HPA037810, HPA056909" Enhanced NA NA 1200000 "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 46: Skeletal myocytes - Muscle structure & formation" "CAB002451: , HPA037810: , HPA056909: " "potential prognostic favorable (5.93e-4)" "unprognostic (9.66e-2)" "unprognostic (1.35e-2)" "unprognostic (3.41e-3)" "unprognostic (3.82e-3)" "unprognostic (9.29e-2)" "unprognostic (1.46e-1)" "unprognostic (2.50e-2)" "unprognostic (1.27e-1)" "unprognostic (7.23e-2)" "unprognostic (2.56e-1)" "unprognostic (1.22e-1)" "unprognostic (6.09e-2)" "unprognostic (8.80e-2)" TNP1 ENSG00000118245 "Transition protein 1" P09430 2 216859458-216860064 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1325 "testis: 5763.6" "Group enriched" "Detected in some" 75 "Early spermatids: 46387.6;Late spermatids: 175963.3" "Not detected" "Not detected" "Group enriched" "Detected in some" 54 "Liver Hepatocellular Carcinoma (TCGA): 13.0;Testicular Germ Cell Tumor (TCGA): 5.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA044387 Enhanced NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 33: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 4 "HPA044387: " "unprognostic (1.82e-2)" "unprognostic (2.27e-1)" TNP2 TP2 ENSG00000178279 "Transition protein 2" Q05952 16 11267748-11269533 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 484 "testis: 48.3" "Cell type enriched" "Detected in some" 5 "Late spermatids: 1316.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 14 TNPO1 "IPO2, KPNB2, MIP, MIP1, TRN" ENSG00000083312 "Transportin 1" Q92973 5 72816312-72916733 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Rod photoreceptor cells: 587.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016325, HPA073832" Approved Supported "Nucleoplasm,Nucleoli,Cytosol,Cytoplasmic bodies" NA NA 150000 "Cluster 33: Non-specific - ATP binding" "Cluster 42: Retina - Visual perception" "Cluster 21: Non-specific - Metabolism" "Cluster 7: Liver cancer - Metabolism" "Cluster 79: Photoreceptor cells - Phototransduction" 69 Nucleoplasm "Nucleoli, Cytosol, Cytoplasmic bodies" "CAB016325: , HPA073832: " "unprognostic (2.81e-1)" "unprognostic (1.25e-1)" "unprognostic (4.15e-1)" "unprognostic (2.05e-2)" "unprognostic (5.61e-2)" "unprognostic (8.73e-2)" "unprognostic (4.38e-1)" "potential prognostic unfavorable (5.00e-4)" "unprognostic (3.87e-2)" "unprognostic (2.32e-2)" "potential prognostic favorable (3.20e-6)" "unprognostic (3.28e-1)" "unprognostic (7.56e-2)" "unprognostic (3.70e-3)" "unprognostic (2.52e-2)" "potential prognostic unfavorable (1.61e-5)" "unprognostic (4.49e-3)" "unprognostic (3.56e-1)" "unprognostic (1.21e-1)" "unprognostic (5.53e-2)" "potential prognostic unfavorable (4.07e-4)" "unprognostic (1.09e-2)" "unprognostic (1.56e-1)" "unprognostic (1.27e-1)" "unprognostic (4.20e-2)" "unprognostic (2.78e-1)" "unprognostic (5.00e-2)" "unprognostic (5.83e-2)" "unprognostic (1.73e-1)" "unprognostic (1.86e-2)" "unprognostic (5.22e-2)" TNPO2 "FLJ12155, IPO3, KPNB2B, TRN2" ENSG00000105576 "Transportin 2" O14787 19 12699201-12724011 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Pancreas - Endothelial cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046446, HPA071498" Approved Approved Nucleoplasm,Nucleoli Yes No 11000 "Cluster 30: Non-specific - DNA binding" "Cluster 2: Non-specific - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 23: Non-specific - Transcription" "Cluster 94: Gonadal somatic cells - Mixed function" 22 "Nucleoplasm, Nucleoli" "CAB046446: , HPA071498: " "unprognostic (1.94e-1)" "unprognostic (8.45e-2)" "unprognostic (3.07e-2)" "unprognostic (6.75e-2)" "unprognostic (4.56e-2)" "unprognostic (3.85e-2)" "unprognostic (1.16e-1)" "unprognostic (2.47e-2)" "unprognostic (1.08e-2)" "unprognostic (4.20e-2)" "potential prognostic favorable (1.66e-4)" "unprognostic (1.05e-1)" "unprognostic (1.38e-3)" "unprognostic (2.37e-2)" "unprognostic (4.96e-2)" "unprognostic (2.47e-1)" "unprognostic (1.74e-2)" "unprognostic (7.84e-3)" "unprognostic (2.90e-2)" "unprognostic (1.57e-1)" "unprognostic (1.66e-1)" "unprognostic (2.65e-2)" "unprognostic (2.91e-2)" "unprognostic (2.68e-2)" "unprognostic (2.67e-2)" "unprognostic (2.43e-3)" "unprognostic (6.94e-2)" "unprognostic (6.39e-2)" "unprognostic (1.06e-1)" "unprognostic (2.63e-2)" "unprognostic (2.25e-1)" TNPO3 "IPO12, LGMD1F, MTR10A, TRN-SR, TRN-SR2" ENSG00000064419 "Transportin 3" Q9Y5L0 7 128954180-129055173 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 430.1;Neutrophils: 481.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039555, HPA072893" Approved Supported Nucleoplasm,Cytosol NA NA 5100 "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 39: Non-specific - Transcription" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 46 Cytosol Nucleoplasm "HPA039555: , HPA072893: " "unprognostic (9.35e-2)" "unprognostic (2.76e-2)" "unprognostic (9.97e-2)" "potential prognostic unfavorable (4.86e-4)" "unprognostic (2.70e-1)" "unprognostic (1.59e-1)" "unprognostic (2.45e-1)" "unprognostic (6.19e-3)" "unprognostic (1.36e-1)" "unprognostic (1.34e-3)" "potential prognostic favorable (5.46e-5)" "unprognostic (1.97e-2)" "unprognostic (1.99e-1)" "potential prognostic unfavorable (2.05e-4)" "unprognostic (1.79e-3)" "unprognostic (2.72e-3)" "unprognostic (9.18e-2)" "unprognostic (5.39e-2)" "unprognostic (4.55e-2)" "unprognostic (7.86e-2)" "unprognostic (3.76e-1)" "unprognostic (9.65e-3)" "unprognostic (2.20e-1)" "unprognostic (1.52e-2)" "unprognostic (7.68e-2)" "unprognostic (2.19e-1)" "unprognostic (1.76e-1)" "unprognostic (1.37e-1)" "unprognostic (4.36e-1)" "unprognostic (1.16e-1)" "unprognostic (8.02e-2)" TNR ENSG00000116147 "Tenascin R" Q92752 1 175315194-175743616 "Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "brain: 38.9;retina: 15.1" "Cell type enhanced" "Detected in many" "Bergmann glia: 776.6;Brain excitatory neurons: 319.5;Gonadotrophs: 259.1;Oligodendrocyte progenitor cells: 4300.5;Oligodendrocytes: 676.3;Retinal horizontal cells: 1811.1" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 3078.1;oligodendrocyte precursor cell: 4920.8" "Cancer enriched" "Detected in single" 32 "Glioblastoma Multiforme (TCGA): 16.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 2.1;thyroid cancer: 3.7" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Beta cells, Pituitary gland - Lactotropes, Spleen - B-cells (Spleen), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022343, HPA027134, HPA027150, HPA029859" Enhanced "Secreted in brain" "Cell adhesion" NA NA 16000 "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 1 "CAB022343: , HPA027134: , HPA027150: , HPA029859: " "unprognostic (3.36e-1)" "potential prognostic favorable (3.02e-5)" "unprognostic (5.15e-3)" TNRC18 "CAGL79, KIAA1856, TNRC18A" ENSG00000182095 "Trinucleotide repeat containing 18" O15417 7 5306790-5425414 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hematopoietic stem cells: 378.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 20.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020730, HPA024251" Uncertain Supported "Nucleoplasm,Nuclear membrane,Mitochondria,Cytosol" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 15: Non-specific - Transcription" "Cluster 67: Non-specific - Unknown function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 12 "Nucleoplasm, Nuclear membrane, Mitochondria" Cytosol "HPA020730: , HPA024251: " "unprognostic (2.30e-2)" "unprognostic (2.63e-1)" "unprognostic (2.69e-1)" "unprognostic (3.24e-3)" "unprognostic (9.66e-2)" "unprognostic (4.44e-2)" "unprognostic (3.29e-1)" "unprognostic (2.15e-1)" "unprognostic (2.03e-1)" "unprognostic (1.80e-1)" "unprognostic (8.23e-3)" "unprognostic (8.11e-3)" "unprognostic (4.05e-2)" "unprognostic (7.37e-2)" "unprognostic (1.56e-1)" "unprognostic (1.05e-1)" "unprognostic (1.59e-2)" "unprognostic (2.36e-1)" "unprognostic (4.12e-3)" "unprognostic (1.10e-2)" "unprognostic (7.82e-2)" "unprognostic (2.10e-1)" "unprognostic (1.37e-1)" "unprognostic (3.28e-1)" "unprognostic (1.28e-2)" "unprognostic (3.72e-1)" "unprognostic (2.41e-1)" "unprognostic (1.10e-1)" "unprognostic (3.89e-1)" "unprognostic (1.90e-2)" "unprognostic (3.57e-2)" TNRC6A "CAGH26, GW182, KIAA1460, TNRC6" ENSG00000090905 "Trinucleotide repeat containing adaptor 6A" Q8NDV7 16 24610209-24827632 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, RNA-mediated gene silencing, Translation regulation" RNA-binding Epilepsy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 1092.7;Brain inhibitory neurons: 891.5;Choroid plexus epithelial cells: 1263.7;Lactotrophs: 998.1;Other brain neurons: 892.0;Retinal pigment epithelial cells: 1244.8;Somatotrophs: 2198.3;Thyrotrophs: 1772.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015305, HPA017869" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 32: Basophils - Transcription" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 54: Non-specific - Transcription" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 57 "Nucleoplasm, Golgi apparatus, Vesicles" "HPA015305: , HPA017869: " "unprognostic (7.87e-2)" "unprognostic (6.48e-2)" "unprognostic (1.24e-2)" "unprognostic (1.17e-1)" "unprognostic (1.68e-1)" "unprognostic (2.69e-1)" "unprognostic (2.24e-2)" "unprognostic (8.45e-3)" "unprognostic (9.67e-3)" "unprognostic (3.24e-2)" "unprognostic (4.08e-2)" "unprognostic (1.70e-2)" "unprognostic (2.09e-1)" "unprognostic (2.28e-1)" "unprognostic (1.40e-2)" "unprognostic (1.96e-1)" "unprognostic (1.23e-1)" "unprognostic (2.18e-1)" "unprognostic (4.69e-2)" "unprognostic (3.45e-2)" "unprognostic (4.72e-2)" "unprognostic (9.23e-2)" "unprognostic (2.19e-3)" "unprognostic (1.93e-1)" "unprognostic (3.11e-2)" "unprognostic (8.09e-3)" "unprognostic (1.43e-1)" "unprognostic (1.09e-1)" "unprognostic (5.30e-2)" "unprognostic (1.68e-2)" "unprognostic (1.14e-1)" TNRC6B KIAA1093 ENSG00000100354 "Trinucleotide repeat containing adaptor 6B" Q9UPQ9 22 40044817-40335808 "Disease related genes, Metabolic proteins, Predicted intracellular proteins" "RNA-mediated gene silencing, Translation regulation" RNA-binding "Autism spectrum disorder, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 1461.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 488.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003180 Approved NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 2: Neurons - Nucleosome" "Cluster 66: Non-specific - Mitochondria" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 55 "HPA003180: " "unprognostic (1.04e-1)" "unprognostic (4.57e-2)" "unprognostic (2.42e-2)" "unprognostic (3.37e-1)" "unprognostic (4.07e-1)" "unprognostic (7.48e-2)" "unprognostic (1.98e-2)" "unprognostic (2.76e-1)" "unprognostic (1.42e-1)" "unprognostic (1.38e-1)" "validated prognostic favorable (5.20e-4)" "validated prognostic favorable (3.62e-5)" "unprognostic (2.18e-2)" "unprognostic (6.71e-2)" "unprognostic (6.36e-2)" "unprognostic (1.01e-1)" "unprognostic (1.94e-1)" "unprognostic (2.03e-2)" "unprognostic (3.89e-3)" "unprognostic (2.37e-1)" "unprognostic (4.89e-2)" "unprognostic (4.95e-3)" "unprognostic (6.81e-2)" "unprognostic (2.51e-1)" "unprognostic (5.99e-3)" "unprognostic (3.21e-3)" "unprognostic (2.80e-1)" "unprognostic (3.67e-2)" "unprognostic (9.14e-2)" "unprognostic (2.19e-2)" "unprognostic (5.94e-2)" TNRC6C "FLJ20015, KIAA1582" ENSG00000078687 "Trinucleotide repeat containing adaptor 6C" Q9HCJ0 17 77958703-78108822 "Predicted intracellular proteins" "RNA-mediated gene silencing, Translation regulation" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 22.8" "Cell type enhanced" "Detected in many" "Retinal amacrine cells: 451.8;Retinal bipolar cells: 509.9;Thyrotrophs: 461.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 13.1" "Lineage enriched" "Detected in many" 5 "granulocytes: 13.1" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts, Testis - Spermatocytes, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022007, HPA062051" Uncertain Approved Nucleoplasm NA NA "Cluster 41: Basophils - Unknown function" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 34: Non-specific - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 50 Nucleoplasm "HPA022007: , HPA062051: " "unprognostic (2.19e-3)" "unprognostic (2.70e-1)" "unprognostic (5.31e-2)" "unprognostic (8.19e-2)" "unprognostic (5.23e-2)" "unprognostic (4.34e-2)" "unprognostic (3.49e-1)" "potential prognostic favorable (3.44e-4)" "unprognostic (1.15e-2)" "unprognostic (9.08e-2)" "validated prognostic favorable (4.05e-6)" "validated prognostic favorable (1.84e-5)" "unprognostic (1.95e-2)" "unprognostic (1.57e-1)" "unprognostic (1.79e-1)" "unprognostic (5.39e-3)" "unprognostic (2.86e-2)" "unprognostic (1.12e-1)" "unprognostic (1.29e-2)" "unprognostic (1.47e-2)" "unprognostic (2.08e-2)" "unprognostic (1.94e-3)" "unprognostic (2.86e-1)" "unprognostic (1.22e-1)" "unprognostic (3.45e-2)" "unprognostic (1.37e-2)" "unprognostic (3.21e-1)" "unprognostic (4.04e-2)" "unprognostic (3.01e-1)" "unprognostic (3.26e-2)" "unprognostic (2.56e-3)" TNS1 "DKFZp586K0617, MXRA6, PPP1R155, TNS" ENSG00000079308 "Tensin 1" Q9HBL0 2 217799588-218033982 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 538.4" "Cell type enhanced" "Detected in many" "Adipocytes: 1235.5;Alveolar cells type 1: 369.3;Leydig cells: 400.9;Pericytes: 459.3;Peritubular myoid cells: 855.9;Proximal tubule cells: 679.9;Salivary myoepithelial cells: 452.6;Smooth muscle cells: 594.4;Vascular smooth muscle cells: 701.6" "Cell type enhanced" "Detected in many" "pericyte: 433.0;vascular associated smooth muscle cell: 517.8" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 143.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 1.8;intermediate monocyte: 7.0;non-classical monocyte: 4.0" "Lineage enriched" "Detected in single" 9 "monocytes: 7.0" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Pituitary gland - Endothelial cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018774, HPA036089, HPA036090" Approved Enhanced "Focal adhesion sites" NA NA 17000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 47: Endothelial cells - Vasculature" "Cluster 47: Leukemia - Hemostasis" "Cluster 62: Smooth muscle cells - Muscle contraction" 2 "Focal adhesion sites" "CAB018774: , HPA036089: , HPA036090: " "unprognostic (1.45e-2)" "unprognostic (7.16e-2)" "unprognostic (3.50e-2)" "unprognostic (2.36e-1)" "unprognostic (1.17e-2)" "unprognostic (9.14e-2)" "unprognostic (1.93e-1)" "unprognostic (1.67e-1)" "unprognostic (1.95e-2)" "unprognostic (1.21e-1)" "validated prognostic favorable (1.14e-9)" "validated prognostic favorable (3.31e-5)" "unprognostic (2.34e-1)" "unprognostic (5.13e-3)" "unprognostic (7.29e-3)" "unprognostic (6.35e-3)" "unprognostic (2.48e-1)" "unprognostic (1.21e-2)" "unprognostic (3.67e-1)" "unprognostic (3.68e-3)" "unprognostic (6.80e-2)" "unprognostic (1.07e-2)" "unprognostic (4.42e-1)" "unprognostic (1.10e-1)" "unprognostic (1.75e-2)" "unprognostic (2.98e-2)" "unprognostic (4.59e-2)" "unprognostic (6.68e-3)" "unprognostic (7.98e-2)" "unprognostic (9.09e-2)" "unprognostic (1.27e-2)" TNS2 "C1-TEN, KIAA1075, TENC1" ENSG00000111077 "Tensin 2" Q63HR2 12 53046969-53064379 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 152.1;Breast lactating cells: 121.5;Fibro-adipogenic progenitors: 97.7;Fibroblasts: 91.6;Leydig cells: 194.9;Pericytes: 152.0;Peritubular myoid cells: 130.8;Podocytes: 129.6;Vascular endothelial cells: 111.0;Vascular smooth muscle cells: 131.0" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 207.6;fibroblast: 187.5;pericyte: 281.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Adipocytes (Breast), Colon - Endothelial cells, Pancreas - Endothelial cells, Pituitary gland - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034659 Approved NA Yes "Cluster 74: Non-specific - Signal transduction" "Cluster 47: Endothelial cells - Vasculature" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 110: Mural cells - ECM organization" 95 "HPA034659: " "unprognostic (8.34e-2)" "unprognostic (1.04e-1)" "unprognostic (1.01e-1)" "unprognostic (1.71e-1)" "unprognostic (7.90e-2)" "unprognostic (6.65e-2)" "unprognostic (1.47e-1)" "unprognostic (2.81e-2)" "unprognostic (1.24e-1)" "validated prognostic favorable (7.40e-5)" "validated prognostic favorable (4.07e-4)" "unprognostic (9.11e-2)" "unprognostic (3.31e-1)" "unprognostic (5.18e-2)" "unprognostic (4.04e-1)" "unprognostic (4.89e-2)" "unprognostic (1.99e-1)" "unprognostic (3.73e-2)" "unprognostic (1.18e-1)" "unprognostic (2.17e-3)" "unprognostic (2.57e-2)" "unprognostic (5.40e-2)" "unprognostic (2.45e-2)" "unprognostic (5.05e-2)" "unprognostic (3.73e-3)" "unprognostic (1.37e-2)" "unprognostic (2.75e-2)" "unprognostic (2.28e-1)" "unprognostic (1.01e-1)" TNS3 "FLJ13732, H_NH0549I23.2, TEM6, TENS1" ENSG00000136205 "Tensin 3" Q68CZ2 7 47275154-47582558 "Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Podocytes: 693.3;Renal collecting duct intercalated cells: 495.2" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 440.5;committed oligodendrocyte precursor: 1548.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 4.3;intermediate monocyte: 2.8;memory B-cell: 2.3;myeloid DC: 3.2;naive B-cell: 1.8;non-classical monocyte: 4.0;plasmacytoid DC: 3.8" "Group enriched" "Detected in many" 6 "B-cells: 2.3;dendritic cells: 3.8;monocytes: 4.3" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Colon - Enteric glia cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055338, HPA056015" Approved Enhanced "Focal adhesion sites" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 36: Brain & Liver - Signaling" "Cluster 44: Non-specific - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 17 "Focal adhesion sites" "HPA055338: , HPA056015: " "unprognostic (5.58e-3)" "unprognostic (9.93e-2)" "unprognostic (1.29e-1)" "unprognostic (6.92e-3)" "unprognostic (2.26e-1)" "unprognostic (1.52e-1)" "unprognostic (5.84e-2)" "unprognostic (2.00e-1)" "unprognostic (6.63e-2)" "unprognostic (6.99e-2)" "potential prognostic favorable (7.81e-6)" "unprognostic (2.03e-3)" "unprognostic (2.56e-1)" "unprognostic (2.26e-1)" "unprognostic (1.63e-1)" "unprognostic (2.25e-1)" "unprognostic (1.45e-3)" "unprognostic (1.39e-1)" "unprognostic (2.33e-1)" "unprognostic (2.06e-2)" "unprognostic (3.12e-2)" "unprognostic (2.39e-1)" "unprognostic (2.18e-2)" "unprognostic (1.05e-1)" "unprognostic (2.90e-2)" "unprognostic (7.43e-3)" "unprognostic (5.25e-2)" "unprognostic (4.71e-2)" "unprognostic (1.45e-1)" "unprognostic (4.88e-2)" "unprognostic (2.19e-1)" TNS4 CTEN ENSG00000131746 "Tensin 4" Q8IZW8 17 40475828-40501623 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 193.9;vagina: 70.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 407.0;Basal prostatic cells: 289.5;Epicardial cells: 270.6;Epididymal basal cells: 259.1;Esophageal basal cells: 265.4;Medullary thymic epithelial cells: 158.4;Ocular epithelial cells: 327.9;Prostatic hillock cells: 161.4;Respiratory basal cells: 193.7;Salivary basal cells: 401.9;Salivary myoepithelial cells: 289.1;Submucosal glandular cells: 151.3;Suprabasal keratinocytes: 133.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 120.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate basal glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA024388, HPA079528" Enhanced Cytosol NA NA "Cluster 58: Skin - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 26: Keratinocytes - Keratinization" 24 Cytosol "HPA024388: , HPA079528: " "unprognostic (1.97e-1)" "unprognostic (1.62e-2)" "unprognostic (1.09e-1)" "unprognostic (2.84e-2)" "unprognostic (1.14e-1)" "unprognostic (4.92e-3)" "unprognostic (2.16e-1)" "unprognostic (7.10e-2)" "unprognostic (3.92e-2)" "potential prognostic unfavorable (2.24e-6)" "unprognostic (3.42e-2)" "unprognostic (5.26e-2)" "unprognostic (3.06e-2)" "unprognostic (2.88e-3)" "unprognostic (2.91e-1)" "unprognostic (1.31e-3)" "unprognostic (2.61e-1)" "unprognostic (2.11e-1)" "unprognostic (2.31e-3)" "unprognostic (1.97e-2)" "unprognostic (1.26e-1)" "unprognostic (2.30e-1)" "unprognostic (5.15e-3)" "unprognostic (1.50e-1)" TNXB "HXBL, TN-X, TNX, TNXB1, TNXB2, TNXBS, XB, XBS" ENSG00000168477 "Tenascin XB" P22105 6 32041153-32115334 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 253.2" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 5.6;Brain inhibitory neurons: 4.5;Ependymal cells: 7.0;Epicardial cells: 18.2;Fibro-adipogenic progenitors: 12.4;Fibroblasts: 15.5;Lymphatic endothelial cells: 19.0;Papillary tip epithelial cells: 5.1;Podocytes: 5.2;Proximal tubule cells: 5.4;Renal collecting duct principal cells: 4.2;Renal connecting tubule cells: 4.8;Vascular endothelial cells: 6.6" "Group enriched" "Detected in many" 4 "endothelial cell: 31.6;fibroblast: 87.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Colon - Fibroblasts, Heart muscle - Fibroblasts, Lung - Fibroblasts_1, Minor Salivary Gland - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblasts_2, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA016017, HPA070464" Supported Vesicles "Secreted to extracellular matrix" "Cell adhesion" NA NA 760000000 "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 15: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 105: Non-specific - Mixed function" 1 Vesicles "HPA016017: , HPA070464: " "unprognostic (1.99e-1)" "unprognostic (7.60e-3)" "unprognostic (3.94e-3)" "unprognostic (1.50e-1)" "unprognostic (3.64e-2)" "unprognostic (1.25e-1)" "unprognostic (1.23e-1)" "unprognostic (4.90e-3)" "unprognostic (6.96e-2)" "unprognostic (1.50e-2)" "unprognostic (1.35e-1)" "potential prognostic favorable (3.72e-6)" "unprognostic (3.30e-3)" "unprognostic (7.04e-2)" "unprognostic (5.98e-3)" "unprognostic (9.35e-2)" "unprognostic (3.42e-2)" "unprognostic (1.57e-1)" "unprognostic (6.86e-2)" "unprognostic (4.36e-2)" "unprognostic (7.50e-2)" "unprognostic (2.85e-2)" TOB1 "APRO5, TOB, TROB, TROB1" ENSG00000141232 "Transducer of ERBB2, 1" P50616 17 50862223-50867978 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 517.2;Ocular epithelial cells: 477.8;Prostatic club cells: 622.2;Prostatic hillock cells: 589.7" "Cell type enhanced" "Detected in all" "astrocyte: 181.4;ependymal cell: 317.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Minor Salivary Gland - Minor salivary gland ductal cells, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" HPA047839 Approved Approved Nucleoplasm,Vesicles NA Yes "Cluster 42: Non-specific - Vesicular transport" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 31 Nucleoplasm Vesicles "HPA047839: " "unprognostic (3.39e-2)" "unprognostic (2.24e-1)" "unprognostic (9.45e-2)" "unprognostic (3.38e-2)" "unprognostic (9.65e-2)" "unprognostic (5.27e-3)" "unprognostic (2.53e-2)" "unprognostic (4.34e-3)" "unprognostic (1.38e-1)" "unprognostic (3.78e-1)" "validated prognostic favorable (1.11e-5)" "validated prognostic favorable (8.10e-5)" "unprognostic (4.04e-2)" "unprognostic (8.20e-2)" "unprognostic (1.94e-1)" "unprognostic (2.14e-1)" "unprognostic (2.05e-3)" "unprognostic (2.66e-2)" "unprognostic (5.46e-2)" "unprognostic (2.06e-1)" "unprognostic (3.62e-3)" "potential prognostic unfavorable (3.30e-4)" "unprognostic (9.44e-2)" "unprognostic (1.34e-2)" "unprognostic (6.60e-2)" "unprognostic (2.28e-2)" "unprognostic (1.49e-1)" "unprognostic (6.41e-2)" "unprognostic (2.65e-1)" "unprognostic (2.09e-2)" "unprognostic (7.65e-3)" TOB2 "APRO5, bK223H9, TOB4, TOBL, TROB2" ENSG00000183864 "Transducer of ERBB2, 2" Q14106 22 41433494-41446801 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016603, HPA054112" Approved Approved Cytosol NA Yes "Cluster 13: Non-specific - Mitochondria" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 66: Non-specific - Mitochondria" "Cluster 103: Non-specific - Basic cellular processes" 12 Cytosol "HPA016603: , HPA054112: " "unprognostic (2.76e-3)" "unprognostic (1.15e-1)" "unprognostic (2.85e-1)" "potential prognostic unfavorable (3.12e-4)" "unprognostic (7.29e-2)" "unprognostic (7.61e-3)" "unprognostic (3.96e-2)" "potential prognostic favorable (2.83e-4)" "unprognostic (5.69e-2)" "unprognostic (2.70e-1)" "validated prognostic favorable (3.45e-9)" "validated prognostic favorable (5.27e-6)" "unprognostic (4.93e-2)" "unprognostic (3.89e-2)" "unprognostic (3.52e-1)" "unprognostic (9.16e-2)" "unprognostic (1.44e-1)" "unprognostic (2.74e-1)" "unprognostic (3.73e-2)" "unprognostic (1.15e-1)" "unprognostic (6.80e-2)" "unprognostic (6.07e-3)" "unprognostic (2.15e-1)" "unprognostic (1.71e-1)" "unprognostic (8.13e-2)" "unprognostic (3.06e-1)" "unprognostic (4.39e-2)" "unprognostic (3.52e-2)" "unprognostic (1.98e-1)" "unprognostic (1.22e-1)" "unprognostic (4.25e-2)" TOE1 "hCaf1z, TOE-1" ENSG00000132773 "Target of EGR1, exonuclease" Q96GM8 1 45340052-45343973 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 45.9;Late primary spermatocytes: 78.2;Megakaryocytes: 49.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053775, HPA069119" Supported Uncertain "Nucleoplasm,Nuclear bodies" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 22: Epididymis - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 37: Non-specific - mRNA processing" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 28 Nucleoplasm "Nuclear bodies" "HPA053775: , HPA069119: " "unprognostic (6.36e-2)" "unprognostic (1.57e-1)" "unprognostic (5.40e-2)" "unprognostic (1.48e-1)" "unprognostic (1.39e-2)" "unprognostic (7.81e-2)" "unprognostic (1.71e-1)" "unprognostic (3.01e-3)" "unprognostic (7.70e-3)" "unprognostic (1.03e-1)" "unprognostic (2.14e-3)" "unprognostic (1.33e-1)" "unprognostic (3.07e-2)" "potential prognostic unfavorable (4.35e-9)" "unprognostic (1.01e-2)" "unprognostic (2.67e-1)" "unprognostic (1.29e-1)" "unprognostic (3.66e-1)" "unprognostic (5.09e-2)" "unprognostic (4.70e-2)" "unprognostic (1.65e-3)" "unprognostic (7.21e-3)" "unprognostic (6.85e-2)" "unprognostic (2.51e-1)" "unprognostic (1.62e-1)" "unprognostic (6.37e-2)" "unprognostic (1.25e-1)" "unprognostic (6.67e-2)" "unprognostic (1.45e-1)" "unprognostic (6.88e-3)" "unprognostic (3.78e-1)" TOGARAM1 "crescerin, Crescerin-1, FAM179B, KIAA0423" ENSG00000198718 "TOG array regulator of axonemal microtubules 1" Q9Y4F4 14 44962190-45074431 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 286.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "basophil: 4.8" "Lineage enriched" "Detected in single" 6 "granulocytes: 4.8" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053559 Uncertain Uncertain "Nuclear speckles,Microtubules,Primary cilium" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 7: Non-specific - Transcription" 2 "Nuclear speckles, Microtubules" "Primary cilium" "HPA053559: " "unprognostic (3.81e-2)" "unprognostic (1.22e-1)" "unprognostic (2.26e-1)" "unprognostic (1.99e-2)" "unprognostic (1.75e-1)" "unprognostic (2.97e-1)" "unprognostic (9.47e-2)" "unprognostic (1.49e-1)" "unprognostic (1.20e-2)" "validated prognostic favorable (2.10e-6)" "validated prognostic favorable (1.67e-4)" "unprognostic (7.88e-2)" "unprognostic (4.50e-2)" "unprognostic (4.04e-1)" "unprognostic (1.58e-1)" "unprognostic (5.72e-2)" "unprognostic (5.25e-1)" "unprognostic (2.47e-1)" "unprognostic (6.44e-2)" "unprognostic (1.24e-3)" "unprognostic (1.48e-2)" "unprognostic (8.09e-2)" "unprognostic (2.17e-1)" "unprognostic (4.32e-2)" "unprognostic (4.21e-2)" "unprognostic (3.98e-2)" "unprognostic (1.98e-1)" "unprognostic (3.12e-1)" "unprognostic (5.84e-2)" TOGARAM2 "Crescerin-2, FAM179A, FLJ43249, LOC165186" ENSG00000189350 "TOG array regulator of axonemal microtubules 2" Q6ZUX3 2 28956611-29052230 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 7.3;fallopian tube: 19.0" "Cell type enhanced" "Detected in many" "Astrocytes: 130.4;Bergmann glia: 433.4;Cardiomyocytes: 158.6;Choroid plexus epithelial cells: 223.8;Endometrial ciliated cells: 196.8;Ependymal cells: 698.6;Epididymal efferent duct ciliated cells: 102.4;Fallopian tube ciliated cells: 211.5;Myonuclei: 119.1;Myosatellite cells: 155.5;Respiratory ciliated cells: 402.1" "Cell type enhanced" "Detected in many" "Bergmann glia: 506.7;ependymal cell: 773.7" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 1.6" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in single" "Rhabdoid: 2.0" "Lung - Respiratory ciliated cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA037561, HPA037562, HPA075216" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 34: Ciliated cells - Cilia assembly & function" "Nucleoplasm, Plasma membrane" "HPA037561: , HPA037562: , HPA075216: " "unprognostic (3.06e-3)" "potential prognostic favorable (9.17e-4)" "unprognostic (6.51e-2)" "unprognostic (2.71e-3)" "unprognostic (1.09e-1)" TOLLIP IL-1RAcPIP ENSG00000078902 "Toll interacting protein" Q9H0E2 11 1274371-1309654 "Plasma proteins, Predicted intracellular proteins" "Autophagy, Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 453.4;Esophageal suprabasal cells: 298.7;Late primary spermatocytes: 236.5;Late spermatids: 828.1;Platelets: 215.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038621, HPA038622" Enhanced Supported "Nucleoplasm,Primary cilium,Primary cilium tip,Cytosol" NA NA 63000 "Cluster 7: Non-specific - Innate immune response" "Cluster 24: Non-specific - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 85: Squamous epithelial cells - Keratinization" 105 Cytosol "Nucleoplasm, Primary cilium, Primary cilium tip" "HPA038621: , HPA038622: " "unprognostic (1.97e-1)" "unprognostic (2.80e-1)" "unprognostic (3.17e-2)" "unprognostic (1.53e-1)" "unprognostic (3.38e-1)" "unprognostic (1.09e-1)" "unprognostic (1.93e-2)" "unprognostic (1.19e-3)" "unprognostic (3.08e-2)" "unprognostic (2.44e-2)" "potential prognostic favorable (9.35e-14)" "unprognostic (1.95e-3)" "potential prognostic favorable (5.96e-4)" "unprognostic (1.52e-1)" "unprognostic (2.37e-2)" "unprognostic (1.11e-1)" "unprognostic (2.83e-1)" "unprognostic (7.59e-3)" "unprognostic (2.16e-1)" "unprognostic (9.44e-2)" "unprognostic (9.80e-3)" "unprognostic (3.24e-2)" "unprognostic (5.52e-2)" "unprognostic (3.38e-1)" "unprognostic (3.72e-1)" "unprognostic (3.44e-1)" "unprognostic (8.13e-2)" "unprognostic (1.69e-1)" "unprognostic (1.40e-1)" "unprognostic (4.34e-1)" "unprognostic (3.54e-1)" TOM1 ENSG00000100284 "Target of myb1 membrane trafficking protein" O60784 22 35299275-35347992 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 212.6" "Cell type enhanced" "Detected in all" "Endometrial glandular cells: 274.2;Esophageal apical cells: 627.3;monocytes: 302.0;Neutrophils: 1088.7;Syncytiotrophoblasts: 381.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001749 Approved Supported "Golgi apparatus,Cytosol" NA NA 16000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 24: Non-specific - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 22 Cytosol "Golgi apparatus" "HPA001749: " "unprognostic (1.58e-2)" "unprognostic (4.24e-2)" "unprognostic (4.61e-2)" "unprognostic (5.53e-2)" "unprognostic (1.44e-1)" "unprognostic (1.28e-1)" "unprognostic (3.69e-2)" "unprognostic (2.49e-1)" "unprognostic (1.88e-2)" "unprognostic (2.59e-1)" "potential prognostic favorable (6.20e-5)" "unprognostic (3.69e-2)" "unprognostic (4.79e-3)" "unprognostic (8.27e-3)" "unprognostic (3.99e-2)" "unprognostic (1.09e-1)" "unprognostic (9.88e-2)" "unprognostic (8.85e-2)" "unprognostic (1.73e-1)" "unprognostic (1.34e-1)" "unprognostic (2.61e-2)" "unprognostic (1.70e-1)" "unprognostic (1.51e-2)" "unprognostic (2.98e-1)" "unprognostic (1.55e-2)" "unprognostic (1.06e-1)" "unprognostic (1.36e-1)" "unprognostic (9.29e-2)" "unprognostic (4.06e-2)" "unprognostic (3.50e-2)" "unprognostic (1.62e-1)" TOM1L1 SRCASM ENSG00000141198 "Target of myb1 like 1 membrane trafficking protein" O75674 17 54899387-54961956 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 310.3;Retinal horizontal cells: 254.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Liver - Hepatocytes, Skin - Mitotic cells (Skin), Spleen - Fibroblasts_1, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022916 Uncertain NA NA "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 19 "HPA022916: " "unprognostic (1.96e-1)" "unprognostic (3.44e-2)" "unprognostic (5.17e-2)" "unprognostic (4.92e-2)" "unprognostic (5.20e-3)" "unprognostic (1.74e-1)" "unprognostic (1.55e-3)" "potential prognostic unfavorable (8.14e-6)" "unprognostic (9.48e-3)" "unprognostic (9.98e-2)" "potential prognostic favorable (8.45e-11)" "unprognostic (3.52e-2)" "unprognostic (1.01e-1)" "unprognostic (1.32e-2)" "unprognostic (6.41e-2)" "unprognostic (1.20e-1)" "unprognostic (1.76e-2)" "unprognostic (3.28e-1)" "unprognostic (6.86e-2)" "unprognostic (2.77e-1)" "unprognostic (2.93e-1)" "unprognostic (1.50e-1)" "unprognostic (4.00e-1)" "unprognostic (8.99e-3)" "unprognostic (1.41e-3)" "unprognostic (2.85e-1)" "unprognostic (2.32e-2)" "unprognostic (8.64e-2)" "unprognostic (1.59e-1)" "unprognostic (3.22e-1)" "unprognostic (3.31e-2)" TOM1L2 ENSG00000175662 "Target of myb1 like 2 membrane trafficking protein" Q6ZVM7 17 17843511-17972422 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 132.0" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 549.5;Podocytes: 919.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skin - Keratinocyte (granular), Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022541, HPA023304" Enhanced Approved "Vesicles,Microtubules,Primary cilium,Basal body" NA NA 19000 "Cluster 21: Neutrophils - Unknown function" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 69: Urothelial cells - Basic cellular functions" 16 "Vesicles, Microtubules, Primary cilium, Basal body" "HPA022541: , HPA023304: " "unprognostic (1.56e-2)" "unprognostic (1.14e-1)" "unprognostic (1.83e-1)" "unprognostic (2.39e-1)" "unprognostic (5.41e-2)" "unprognostic (3.84e-2)" "unprognostic (1.01e-1)" "unprognostic (5.33e-2)" "unprognostic (1.78e-3)" "unprognostic (5.63e-2)" "validated prognostic favorable (6.36e-6)" "validated prognostic favorable (3.77e-4)" "potential prognostic favorable (4.74e-6)" "unprognostic (4.92e-1)" "unprognostic (2.76e-3)" "unprognostic (1.70e-2)" "unprognostic (1.27e-1)" "unprognostic (1.07e-1)" "unprognostic (5.87e-2)" "unprognostic (1.37e-3)" "unprognostic (1.98e-1)" "potential prognostic favorable (8.85e-4)" "unprognostic (1.18e-2)" "unprognostic (9.88e-2)" "unprognostic (8.55e-2)" "unprognostic (1.00e-1)" "unprognostic (3.33e-2)" "unprognostic (1.58e-1)" "unprognostic (4.04e-1)" "unprognostic (8.19e-2)" "unprognostic (3.48e-1)" TOMM20 "KIAA0016, MAS20, MOM19, TOM20" ENSG00000173726 "Translocase of outer mitochondrial membrane 20" Q15388 1 235109341-235128837 "Essential proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Gastric progenitor cells: 1085.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005585, HPA011562" Supported Enhanced Mitochondria NA NA 81000 "Cluster 30: Non-specific - DNA binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 14: Neurons - Synaptic function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 15: Non-specific - Protein processing" 46 Mitochondria "CAB005585: , HPA011562: " "unprognostic (2.58e-1)" "unprognostic (8.04e-2)" "unprognostic (1.40e-2)" "potential prognostic unfavorable (1.31e-4)" "unprognostic (1.07e-2)" "unprognostic (7.59e-2)" "unprognostic (6.81e-2)" "unprognostic (2.45e-1)" "unprognostic (3.01e-2)" "unprognostic (1.97e-1)" "potential prognostic favorable (4.98e-9)" "unprognostic (9.31e-3)" "unprognostic (2.27e-2)" "unprognostic (5.37e-3)" "unprognostic (1.30e-2)" "unprognostic (7.82e-2)" "unprognostic (2.82e-3)" "unprognostic (2.06e-1)" "unprognostic (1.41e-2)" "unprognostic (1.24e-1)" "unprognostic (6.33e-2)" "unprognostic (4.33e-3)" "unprognostic (1.93e-1)" "unprognostic (3.65e-2)" "unprognostic (5.10e-2)" "unprognostic (2.83e-1)" "unprognostic (6.66e-2)" "unprognostic (3.34e-2)" "unprognostic (2.97e-1)" "unprognostic (1.50e-2)" "unprognostic (3.39e-2)" TOMM20L UNQ9438 ENSG00000196860 "Translocase of outer mitochondrial membrane 20 like" Q6UXN7 14 58395928-58408702 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 11 "testis: 10.4" "Group enriched" "Detected in some" 12 "Early spermatids: 133.0;Late primary spermatocytes: 129.5" "Cell type enhanced" "Detected in single" "central nervous system macrophage: 1.6" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA076397 Enhanced NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 25: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 4 "HPA076397: " "unprognostic (2.54e-1)" "unprognostic (1.99e-2)" "unprognostic (1.43e-2)" TOMM22 TOM22 ENSG00000100216 "Translocase of outer mitochondrial membrane 22" Q9NS69 22 38681957-38685421 "Essential proteins, Predicted membrane proteins" "Protein transport, Translocation, Transport" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 367.6;Esophageal suprabasal cells: 368.3;Extravillous trophoblasts: 262.5;Migrating cytotrophoblasts: 255.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003037, HPA074642" Supported Enhanced Mitochondria NA NA 28000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 45: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 97: Non-specific - Cellular respiration" 61 Mitochondria "HPA003037: , HPA074642: " "unprognostic (2.52e-1)" "unprognostic (1.25e-1)" "unprognostic (2.73e-2)" "unprognostic (3.77e-1)" "unprognostic (1.53e-1)" "unprognostic (1.47e-1)" "unprognostic (2.76e-1)" "unprognostic (4.54e-1)" "potential prognostic unfavorable (3.40e-4)" "unprognostic (3.61e-3)" "unprognostic (2.96e-3)" "unprognostic (1.05e-1)" "unprognostic (9.39e-3)" "validated prognostic unfavorable (3.97e-5)" "validated prognostic unfavorable (4.46e-7)" "unprognostic (1.15e-3)" "unprognostic (6.76e-2)" "unprognostic (1.34e-1)" "unprognostic (1.19e-2)" "unprognostic (3.48e-2)" "unprognostic (6.54e-2)" "unprognostic (5.01e-3)" "unprognostic (2.35e-1)" "unprognostic (9.33e-2)" "unprognostic (9.01e-3)" "unprognostic (1.31e-1)" "unprognostic (1.13e-1)" "unprognostic (1.36e-1)" "unprognostic (6.00e-1)" "unprognostic (1.05e-1)" "unprognostic (4.31e-2)" TOMM34 "HTOM34P, TOM34" ENSG00000025772 "Translocase of outer mitochondrial membrane 34" Q15785 20 44942130-44960397 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 119.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 163.4;Migrating cytotrophoblasts: 95.1;Oocytes: 207.2;Undifferentiated spermatogonia: 82.2;Urothelial cells: 78.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018845, HPA056875" Enhanced Supported Vesicles,Mitochondria,Cytosol NA NA 7400 "Cluster 23: B-cells - Immunoglobulins" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 51: Neurons - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 32 Cytosol "Vesicles, Mitochondria" "HPA018845: , HPA056875: " "unprognostic (5.47e-2)" "unprognostic (5.97e-3)" "unprognostic (2.19e-1)" "unprognostic (3.14e-2)" "unprognostic (2.39e-2)" "unprognostic (1.27e-1)" "unprognostic (4.22e-1)" "unprognostic (1.03e-1)" "potential prognostic unfavorable (2.19e-4)" "unprognostic (2.84e-1)" "unprognostic (1.07e-1)" "unprognostic (1.02e-2)" "unprognostic (5.53e-2)" "validated prognostic unfavorable (1.68e-6)" "validated prognostic unfavorable (1.68e-4)" "unprognostic (7.68e-2)" "unprognostic (1.07e-3)" "unprognostic (2.65e-2)" "unprognostic (6.50e-2)" "unprognostic (2.76e-1)" "unprognostic (3.51e-1)" "unprognostic (2.48e-1)" "unprognostic (2.60e-1)" "unprognostic (1.10e-1)" "unprognostic (4.58e-2)" "unprognostic (4.10e-2)" "unprognostic (1.87e-1)" "unprognostic (2.59e-1)" "unprognostic (1.36e-1)" "unprognostic (4.14e-2)" "unprognostic (2.90e-3)" TOMM40 "C19orf1, D19S1177E, PER-EC1, PEREC1, TOM40" ENSG00000130204 "Translocase of outer mitochondrial membrane 40" O96008 19 44890569-44903689 "Essential proteins, Predicted intracellular proteins, Transporters" "Ion transport, Protein transport, Transport" Porin "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 250.8;Esophageal suprabasal cells: 154.1;Extravillous trophoblasts: 179.1;Migrating cytotrophoblasts: 172.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036231, HPA036232" Supported Enhanced Mitochondria,Cytosol NA NA 52000 "Cluster 45: Eosinophils - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 4: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 87 Mitochondria Cytosol "HPA036231: , HPA036232: " "unprognostic (1.12e-2)" "unprognostic (4.99e-2)" "unprognostic (2.23e-1)" "unprognostic (6.94e-2)" "unprognostic (4.22e-2)" "unprognostic (1.52e-1)" "unprognostic (1.16e-1)" "unprognostic (1.43e-1)" "unprognostic (4.62e-2)" "unprognostic (9.31e-2)" "unprognostic (8.45e-3)" "unprognostic (1.26e-3)" "unprognostic (3.86e-2)" "validated prognostic unfavorable (1.58e-4)" "validated prognostic unfavorable (3.21e-4)" "potential prognostic unfavorable (2.54e-4)" "unprognostic (1.24e-2)" "unprognostic (2.97e-2)" "unprognostic (6.00e-3)" "unprognostic (1.04e-1)" "unprognostic (8.85e-2)" "unprognostic (1.22e-1)" "unprognostic (5.28e-2)" "unprognostic (4.11e-3)" "unprognostic (2.88e-1)" "unprognostic (9.75e-2)" "unprognostic (2.75e-1)" "unprognostic (4.56e-2)" "unprognostic (2.66e-1)" "unprognostic (6.08e-2)" "unprognostic (4.81e-2)" TOMM40L "FLJ12770, TOMM40B" ENSG00000158882 "Translocase of outer mitochondrial membrane 40 like" Q969M1 1 161225939-161230746 "Predicted intracellular proteins" "Ion transport, Protein transport, Transport" Porin "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 47.9" "Cell type enhanced" "Detected in many" "Megakaryocytes: 30.9;monocytes: 17.3;Neutrophils: 27.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051304 Approved NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" "HPA051304: " "potential prognostic unfavorable (3.81e-4)" "unprognostic (4.40e-2)" "unprognostic (1.03e-1)" "unprognostic (2.73e-2)" "unprognostic (3.59e-2)" "unprognostic (9.96e-2)" "unprognostic (1.17e-1)" "potential prognostic favorable (8.80e-5)" "unprognostic (1.23e-1)" "unprognostic (2.77e-1)" "potential prognostic favorable (3.12e-5)" "unprognostic (1.22e-1)" "unprognostic (1.17e-2)" "unprognostic (2.65e-3)" "unprognostic (4.86e-2)" "unprognostic (6.23e-2)" "unprognostic (2.31e-3)" "unprognostic (1.05e-1)" "unprognostic (1.98e-1)" "unprognostic (1.68e-1)" "unprognostic (1.65e-1)" "unprognostic (1.11e-1)" "unprognostic (3.11e-1)" "unprognostic (2.89e-1)" "unprognostic (2.35e-1)" "unprognostic (1.81e-2)" "unprognostic (1.12e-1)" "unprognostic (4.41e-1)" "unprognostic (3.68e-1)" "unprognostic (4.38e-2)" "unprognostic (1.15e-2)" TOMM5 "bA613M10.3, C9orf105, Tom5" ENSG00000175768 "Translocase of outer mitochondrial membrane 5" Q8N4H5 9 37582646-37592604 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 114.3;Gastric chief cells: 73.2;Hepatocytes: 66.5;Late primary spermatocytes: 156.8;Late spermatids: 122.7;Megakaryocytes: 61.8;Parietal cells: 81.3;Suprabasal keratinocytes: 67.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" HPA048712 Approved Supported Mitochondria NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 97: Non-specific - Cellular respiration" 6 Mitochondria "HPA048712: " "unprognostic (1.14e-2)" "unprognostic (4.04e-2)" "unprognostic (1.20e-2)" "unprognostic (7.58e-2)" "unprognostic (3.52e-1)" "unprognostic (2.59e-1)" "unprognostic (1.00e-1)" "unprognostic (1.62e-3)" "unprognostic (3.78e-2)" "potential prognostic unfavorable (6.27e-4)" "unprognostic (4.78e-3)" "unprognostic (3.46e-1)" "potential prognostic unfavorable (9.02e-4)" "validated prognostic unfavorable (2.39e-5)" "validated prognostic unfavorable (5.06e-5)" "unprognostic (1.33e-3)" "potential prognostic unfavorable (8.99e-4)" "unprognostic (2.48e-2)" "unprognostic (4.33e-2)" "unprognostic (1.15e-2)" "unprognostic (6.82e-2)" "unprognostic (7.88e-2)" "unprognostic (1.28e-2)" "unprognostic (5.43e-2)" "unprognostic (2.74e-1)" "unprognostic (1.75e-1)" "unprognostic (7.43e-3)" "unprognostic (4.64e-2)" "unprognostic (1.49e-1)" "unprognostic (1.66e-1)" "unprognostic (1.24e-1)" TOMM6 "OBTP, Tom6" ENSG00000214736 "Translocase of outer mitochondrial membrane 6" Q96B49 6 41787662-41789898 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 9 "Astrocytes: 29.9;Bergmann glia: 26.0;Brain excitatory neurons: 27.2;Brain inhibitory neurons: 25.1;Choroid plexus epithelial cells: 9.2;Ependymal cells: 28.8;Microglia: 18.5;Oligodendrocyte progenitor cells: 19.2;Oligodendrocytes: 31.1;Other brain neurons: 35.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004801 Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 28: Non-specific - Nuclear processes" "Cluster 98: Neurons - Neurotransmission & signaling" 9 Mitochondria "HPA004801: " "unprognostic (3.11e-1)" "unprognostic (1.60e-3)" "unprognostic (2.22e-1)" "unprognostic (2.57e-1)" "unprognostic (3.45e-2)" "unprognostic (1.86e-1)" "unprognostic (1.03e-1)" "unprognostic (6.50e-3)" "unprognostic (2.43e-3)" "unprognostic (6.90e-2)" "unprognostic (2.84e-2)" "unprognostic (1.35e-1)" "validated prognostic unfavorable (8.85e-4)" "validated prognostic unfavorable (5.38e-7)" "unprognostic (1.03e-2)" "unprognostic (3.37e-2)" "unprognostic (4.35e-3)" "unprognostic (8.57e-2)" "unprognostic (4.11e-3)" "unprognostic (1.30e-1)" "unprognostic (2.75e-1)" "unprognostic (2.40e-1)" "unprognostic (2.75e-1)" "unprognostic (1.26e-1)" "unprognostic (2.16e-1)" "unprognostic (2.78e-3)" "unprognostic (3.32e-2)" "unprognostic (2.42e-1)" "unprognostic (2.54e-1)" "unprognostic (2.11e-1)" TOMM7 Tom7 ENSG00000196683 "Translocase of outer mitochondrial membrane 7" Q9P0U1 7 22812628-22822849 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Ribosome" "Cluster 67: Non-specific - Unknown function" "Cluster 15: Non-specific - Protein processing" 3 "unprognostic (2.58e-3)" "unprognostic (1.93e-1)" "unprognostic (1.09e-1)" "unprognostic (8.72e-3)" "unprognostic (3.94e-3)" "unprognostic (5.22e-2)" "unprognostic (4.63e-3)" "unprognostic (3.16e-3)" "potential prognostic unfavorable (5.73e-5)" "unprognostic (1.43e-3)" "potential prognostic favorable (6.70e-5)" "unprognostic (1.42e-1)" "unprognostic (3.82e-1)" "unprognostic (3.46e-3)" "potential prognostic unfavorable (9.34e-6)" "unprognostic (8.44e-3)" "unprognostic (1.07e-1)" "unprognostic (4.78e-3)" "unprognostic (2.36e-1)" "unprognostic (1.40e-1)" "unprognostic (2.18e-2)" "unprognostic (5.70e-3)" "unprognostic (1.74e-1)" "unprognostic (1.74e-1)" "unprognostic (1.89e-1)" "unprognostic (3.56e-1)" "unprognostic (1.67e-1)" "unprognostic (3.22e-2)" "unprognostic (1.31e-1)" "unprognostic (2.57e-1)" "unprognostic (1.42e-1)" TOMM70 "KIAA0719, Tom70, TOMM70A" ENSG00000154174 "Translocase of outer mitochondrial membrane 70" O94826 3 100363431-100401089 "Predicted membrane proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014589, CAB017156, HPA048020" Enhanced Enhanced Mitochondria NA NA 47000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 33: Neurons - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 35: Neurons - Synaptic function & neurogenesis" 23 Mitochondria "CAB017156: , HPA014589: , HPA048020: " "unprognostic (2.18e-1)" "unprognostic (2.94e-3)" "unprognostic (3.49e-2)" "unprognostic (1.06e-1)" "unprognostic (3.29e-1)" "unprognostic (1.05e-1)" "unprognostic (2.67e-2)" "unprognostic (2.75e-1)" "potential prognostic unfavorable (9.80e-5)" "potential prognostic favorable (3.23e-5)" "unprognostic (3.02e-1)" "potential prognostic favorable (7.92e-4)" "unprognostic (4.49e-3)" "unprognostic (1.81e-2)" "potential prognostic unfavorable (4.16e-4)" "unprognostic (4.15e-1)" "unprognostic (1.52e-1)" "unprognostic (3.76e-2)" "unprognostic (7.74e-3)" "unprognostic (5.50e-3)" "unprognostic (2.31e-1)" "unprognostic (2.54e-2)" "potential prognostic favorable (1.35e-4)" "unprognostic (2.93e-1)" "unprognostic (5.60e-2)" "unprognostic (1.36e-1)" "unprognostic (3.55e-1)" "unprognostic (5.33e-2)" "unprognostic (2.02e-1)" TOMT COMT2 ENSG00000284844 "Transmembrane O-methyltransferase" 11 72105924-72109596 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pituitary gland - Gonadotropes, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 11: Neuronal - Sensory perception" TONSL "IKBR, NFKBIL2" ENSG00000160949 "Tonsoku like, DNA repair protein" Q96HA7 8 144428775-144444440 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins, Transcription factors" "DNA damage, DNA repair" "Chromatin regulator" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 8.0" "Cell type enhanced" "Detected in some" "Enterocytes: 4.0;Erythrocyte progenitors: 4.7;Hepatic stellate cells: 6.5;Megakaryocyte progenitors: 4.2;Papillary tip epithelial cells: 3.3;Proximal tubule cells: 3.3;Renal collecting duct principal cells: 2.9;Tuft cells: 11.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA024679, HPA046494" Uncertain Supported "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 44: Bone marrow - Nuclear processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 40: Non-specific - Unknown function" "Cluster 104: Brain endothelial cells - Blood brain barrier" 58 Nucleoplasm "Nuclear bodies" "HPA024679: , HPA046494: " "unprognostic (2.57e-2)" "unprognostic (4.02e-2)" "unprognostic (3.90e-2)" "unprognostic (1.15e-1)" "unprognostic (8.40e-3)" "unprognostic (1.09e-1)" "unprognostic (8.49e-3)" "unprognostic (8.95e-2)" "unprognostic (4.49e-2)" "unprognostic (8.89e-2)" "potential prognostic unfavorable (1.01e-5)" "unprognostic (1.59e-3)" "validated prognostic unfavorable (2.52e-6)" "validated prognostic unfavorable (1.50e-5)" "potential prognostic unfavorable (1.83e-4)" "unprognostic (1.58e-3)" "unprognostic (1.34e-1)" "unprognostic (1.41e-1)" "unprognostic (1.21e-1)" "unprognostic (1.64e-2)" "unprognostic (3.44e-2)" "potential prognostic unfavorable (9.50e-5)" "unprognostic (5.83e-2)" "unprognostic (9.82e-2)" "unprognostic (4.66e-1)" "unprognostic (2.45e-1)" "unprognostic (1.24e-2)" "unprognostic (1.78e-1)" "unprognostic (7.24e-2)" "unprognostic (1.46e-1)" TOP1 ENSG00000198900 "DNA topoisomerase I" P11387 20 41028822-41124487 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, FDA approved drug targets, Predicted intracellular proteins" "Biological rhythms, Host-virus interaction" "DNA-binding, Isomerase, Topoisomerase" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 1249.6;Neutrophils: 1184.4;Syncytiotrophoblasts: 1442.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Mitotic cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009058, HPA019039" Supported Supported "Nucleoplasm,Nucleoli fibrillar center" No Yes 5400 "Cluster 29: Non-specific - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 16: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 416 "Nucleoplasm, Nucleoli fibrillar center" "CAB009058: , HPA019039: " "unprognostic (2.07e-2)" "unprognostic (1.95e-2)" "unprognostic (3.01e-1)" "unprognostic (7.66e-2)" "unprognostic (3.48e-2)" "unprognostic (2.96e-1)" "unprognostic (1.99e-1)" "unprognostic (2.06e-1)" "unprognostic (5.51e-3)" "unprognostic (4.49e-3)" "unprognostic (2.10e-3)" "unprognostic (7.38e-2)" "unprognostic (1.55e-2)" "potential prognostic unfavorable (2.55e-4)" "unprognostic (5.84e-3)" "unprognostic (6.18e-3)" "potential prognostic unfavorable (1.37e-4)" "unprognostic (8.72e-2)" "unprognostic (7.57e-2)" "unprognostic (1.92e-1)" "unprognostic (3.36e-3)" "unprognostic (5.78e-3)" "potential prognostic unfavorable (1.85e-5)" "unprognostic (6.68e-2)" "unprognostic (8.02e-2)" "unprognostic (7.46e-2)" "unprognostic (9.93e-2)" "unprognostic (7.55e-2)" "unprognostic (2.09e-1)" "unprognostic (6.59e-2)" "unprognostic (2.44e-1)" TOP1MT ENSG00000184428 "DNA topoisomerase I mitochondrial" Q969P6 8 143304384-143359979 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "DNA-binding, Isomerase, Topoisomerase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 60.4;Esophageal basal cells: 53.7;Late primary spermatocytes: 60.0;Undifferentiated spermatogonia: 52.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001915, HPA021542" Approved Supported Mitochondria NA NA "Cluster 18: Non-specific - Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 106: Spermatogonia - Spermatogonial differentiation" Mitochondria "HPA001915: , HPA021542: " "unprognostic (3.23e-2)" "unprognostic (3.20e-2)" "unprognostic (1.17e-1)" "unprognostic (9.21e-3)" "unprognostic (4.76e-2)" "unprognostic (4.02e-1)" "unprognostic (5.06e-2)" "unprognostic (4.97e-2)" "unprognostic (7.14e-3)" "potential prognostic unfavorable (8.10e-4)" "unprognostic (4.00e-1)" "unprognostic (2.23e-1)" "potential prognostic unfavorable (1.88e-4)" "potential prognostic unfavorable (2.64e-4)" "unprognostic (2.07e-2)" "unprognostic (1.72e-1)" "unprognostic (2.33e-2)" "unprognostic (4.21e-2)" "unprognostic (8.57e-2)" "unprognostic (3.88e-2)" "unprognostic (3.68e-1)" "unprognostic (1.30e-2)" "unprognostic (1.21e-1)" "unprognostic (3.02e-2)" "unprognostic (1.33e-1)" "unprognostic (8.52e-2)" "unprognostic (6.09e-2)" "unprognostic (1.20e-1)" "unprognostic (7.37e-2)" "unprognostic (1.66e-2)" "unprognostic (1.02e-1)" TOP2A "TOP2, TOP2alpha, TOPIIA" ENSG00000131747 "DNA topoisomerase II alpha" P11388 17 40388525-40417896 "Cancer-related genes, Enzymes, Essential proteins, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Biological rhythms" "DNA-binding, Isomerase, Topoisomerase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 119.0;testis: 62.4" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 211.0;Early primary spermatocytes: 818.4;Enteric transient amplifying cells: 152.2;Erythrocyte progenitors: 500.6;Gastric progenitor cells: 126.9;Hofbauer cells: 172.0;Late primary spermatocytes: 140.7;Megakaryocyte progenitors: 334.6;Monocyte progenitors: 686.4;Neutrophil progenitors: 176.4" "Cell type enriched" "Detected in single" 4 "leukocyte: 3.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "T-reg: 2.4" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Group enriched" "Detected in many" 4 "basal ganglia: 4.2;white matter: 8.0" "Low region specificity" "Detected in many" "CAB002448, HPA006458, HPA026773" Enhanced Approved Supported Nucleoplasm,Nucleoli Yes Yes 8800 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 12: Non-specific - Vasculature" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 27: Non-specific - Cell proliferation" 235 Nucleoplasm Nucleoli "CAB002448: , HPA006458: , HPA026773: " "unprognostic (6.46e-2)" "unprognostic (2.94e-1)" "unprognostic (1.81e-1)" "unprognostic (2.29e-3)" "unprognostic (3.78e-2)" "unprognostic (4.02e-3)" "unprognostic (9.86e-2)" "unprognostic (2.01e-2)" "unprognostic (7.66e-2)" "potential prognostic unfavorable (2.50e-6)" "validated prognostic unfavorable (1.23e-10)" "validated prognostic unfavorable (3.57e-6)" "potential prognostic unfavorable (4.32e-8)" "validated prognostic unfavorable (5.06e-5)" "validated prognostic unfavorable (5.19e-7)" "potential prognostic unfavorable (3.30e-5)" "unprognostic (1.47e-3)" "unprognostic (1.76e-3)" "unprognostic (7.58e-2)" "unprognostic (1.31e-1)" "unprognostic (3.90e-1)" "unprognostic (1.76e-3)" "unprognostic (1.32e-2)" "unprognostic (3.99e-2)" "unprognostic (2.25e-1)" "potential prognostic favorable (5.55e-4)" "unprognostic (3.72e-3)" "unprognostic (8.19e-2)" "unprognostic (1.82e-1)" "unprognostic (3.45e-2)" "unprognostic (6.49e-2)" TOP2B "top2beta, TOPIIB" ENSG00000077097 "DNA topoisomerase II beta" Q02880 3 25597978-25664909 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA-binding, Isomerase, Topoisomerase" "Autism spectrum disorder, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004601, HPA024120, HPA050441" Supported Enhanced Nucleoplasm NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 31: Non-specific - Transcription" "Cluster 6: Leukemia - Signal transduction" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 42 Nucleoplasm "CAB004601: , HPA024120: , HPA050441: " "unprognostic (8.37e-3)" "unprognostic (1.61e-2)" "unprognostic (1.76e-1)" "unprognostic (3.55e-2)" "unprognostic (1.06e-1)" "unprognostic (1.58e-1)" "unprognostic (5.38e-2)" "unprognostic (3.73e-3)" "unprognostic (7.35e-3)" "unprognostic (6.35e-3)" "potential prognostic favorable (2.56e-5)" "unprognostic (7.01e-3)" "unprognostic (1.04e-1)" "unprognostic (2.05e-3)" "unprognostic (2.90e-2)" "unprognostic (2.18e-1)" "unprognostic (3.31e-2)" "unprognostic (3.61e-1)" "unprognostic (1.37e-2)" "unprognostic (9.47e-2)" "unprognostic (2.96e-1)" "unprognostic (1.14e-1)" "unprognostic (2.20e-1)" "unprognostic (8.88e-2)" "potential prognostic favorable (9.51e-5)" "unprognostic (5.22e-2)" "unprognostic (5.16e-2)" "unprognostic (2.32e-1)" "unprognostic (9.14e-2)" "unprognostic (9.89e-2)" "unprognostic (2.97e-1)" TOP3A "TOP3, ZGRF7" ENSG00000177302 "DNA topoisomerase III alpha" Q13472 17 18271428-18315007 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA-binding, Isomerase, Topoisomerase" "Cancer-related genes, Disease variant, Dwarfism, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 15.8;Bergmann glia: 16.2;Brain excitatory neurons: 28.2;Brain inhibitory neurons: 28.4;Choroid plexus epithelial cells: 31.6;Distal convoluted tubule cells: 24.1;Ependymal cells: 16.0;Loop of henle epithelial cells: 19.6;Microglia: 16.8;Oligodendrocyte progenitor cells: 22.8;Oligodendrocytes: 20.7;Other brain neurons: 25.3;Papillary tip epithelial cells: 14.2;Podocytes: 16.0;Proximal tubule cells: 21.3;Renal collecting duct intercalated cells: 27.8;Renal collecting duct principal cells: 16.6;Renal connecting tubule cells: 19.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB002449 Approved NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 24: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 102: Non-specific - Mixed function" 19 "CAB002449: " "unprognostic (6.32e-2)" "unprognostic (3.67e-2)" "unprognostic (1.99e-1)" "unprognostic (2.33e-2)" "unprognostic (1.32e-1)" "unprognostic (1.95e-1)" "unprognostic (1.46e-1)" "unprognostic (5.99e-3)" "unprognostic (5.74e-3)" "unprognostic (5.93e-3)" "unprognostic (9.19e-3)" "unprognostic (1.58e-2)" "unprognostic (2.63e-1)" "potential prognostic unfavorable (1.10e-4)" "unprognostic (2.15e-1)" "unprognostic (2.01e-1)" "unprognostic (4.59e-2)" "unprognostic (9.74e-2)" "unprognostic (9.24e-2)" "unprognostic (2.87e-1)" "unprognostic (2.06e-2)" "unprognostic (3.01e-3)" "potential prognostic unfavorable (2.29e-5)" "unprognostic (6.03e-3)" "unprognostic (8.42e-2)" "unprognostic (2.66e-1)" "unprognostic (5.23e-2)" "unprognostic (5.34e-3)" "unprognostic (4.80e-2)" "potential prognostic unfavorable (3.59e-5)" "unprognostic (2.16e-1)" TOP3B ENSG00000100038 "DNA topoisomerase III beta" O95985 22 21957025-21982813 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA-binding, Isomerase, Topoisomerase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072114 Approved Nucleoplasm NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 49: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 7: Non-specific - Transcription" 113 Nucleoplasm "HPA072114: " "unprognostic (4.01e-2)" "unprognostic (8.42e-2)" "unprognostic (3.11e-1)" "unprognostic (7.99e-2)" "unprognostic (3.41e-1)" "unprognostic (3.67e-1)" "unprognostic (8.21e-2)" "unprognostic (1.18e-3)" "unprognostic (3.57e-2)" "unprognostic (3.93e-3)" "unprognostic (2.29e-1)" "unprognostic (2.08e-2)" "unprognostic (3.09e-2)" "potential prognostic unfavorable (1.66e-4)" "unprognostic (1.68e-1)" "unprognostic (1.66e-1)" "unprognostic (4.41e-2)" "unprognostic (9.75e-3)" "unprognostic (1.52e-2)" "unprognostic (2.55e-1)" "unprognostic (3.14e-2)" "unprognostic (2.21e-1)" "unprognostic (6.01e-3)" "unprognostic (5.90e-3)" "unprognostic (1.92e-3)" "unprognostic (1.14e-3)" "unprognostic (1.10e-1)" "unprognostic (2.96e-2)" "unprognostic (1.48e-1)" "unprognostic (7.62e-2)" "unprognostic (2.17e-1)" TOPAZ1 "C3orf77, FLJ36157" ENSG00000173769 "Testis and ovary specific TOPAZ 1" Q8N9V7 3 44241886-44332098 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 33 "testis: 3.3" "Group enriched" "Detected in some" 7 "Differentiating spermatogonia: 76.3;Early primary spermatocytes: 217.1;Undifferentiated spermatogonia: 82.3" "Cell type enhanced" "Detected in many" "hippocampal CA1-3: 5.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA047431, HPA051034" Uncertain Approved "Acrosome,Mid piece" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 3: Early primary spermatocytes - Early meiosis" "Acrosome, Mid piece" "HPA047431: , HPA051034: " TOPBP1 "Dpb11, KIAA0259, TOP2BP1" ENSG00000163781 "DNA topoisomerase II binding protein 1" Q92547 3 133598175-133662380 "Essential proteins, Predicted intracellular proteins" "DNA damage, DNA repair" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 128.7;Late spermatids: 156.4;Monocyte progenitors: 170.4;Neutrophil progenitors: 204.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022451, HPA036738, HPA036739" Approved Supported "Nucleoplasm,Nuclear bodies,Plasma membrane" No No "Cluster 42: Non-specific - Vesicular transport" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 34: Non-specific - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 59 "Nucleoplasm, Nuclear bodies" "Plasma membrane" "CAB022451: , HPA036738: , HPA036739: " "unprognostic (5.84e-2)" "unprognostic (4.23e-2)" "unprognostic (1.07e-1)" "unprognostic (3.33e-1)" "unprognostic (2.67e-1)" "unprognostic (3.05e-1)" "unprognostic (2.52e-1)" "unprognostic (4.13e-3)" "unprognostic (5.41e-2)" "potential prognostic unfavorable (5.26e-4)" "unprognostic (2.40e-2)" "unprognostic (2.86e-1)" "unprognostic (7.26e-2)" "potential prognostic unfavorable (1.05e-4)" "unprognostic (1.13e-2)" "unprognostic (3.98e-2)" "unprognostic (2.84e-3)" "unprognostic (5.13e-2)" "unprognostic (6.97e-2)" "unprognostic (2.68e-1)" "unprognostic (2.64e-1)" "unprognostic (1.33e-3)" "potential prognostic unfavorable (4.09e-4)" "unprognostic (6.13e-3)" "potential prognostic favorable (7.14e-4)" "unprognostic (4.08e-2)" "unprognostic (6.60e-2)" "unprognostic (1.37e-1)" "unprognostic (2.04e-1)" "unprognostic (2.00e-1)" "unprognostic (2.39e-1)" TOPORS "LUN, RP31, TP53BPL" ENSG00000197579 "TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase" Q9NS56 9 32540544-32552586 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, Ubl conjugation pathway" Transferase "Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 17.0;Bergmann glia: 23.2;Brain excitatory neurons: 19.8;Brain inhibitory neurons: 18.4;Choroid plexus epithelial cells: 24.9;Distal convoluted tubule cells: 19.1;Ependymal cells: 11.9;Loop of henle epithelial cells: 19.6;Microglia: 23.2;Oligodendrocyte progenitor cells: 17.2;Oligodendrocytes: 23.7;Other brain neurons: 23.4;Papillary tip epithelial cells: 15.9;Podocytes: 24.8;Proximal tubule cells: 32.4;Renal collecting duct intercalated cells: 24.7;Renal collecting duct principal cells: 14.6;Renal connecting tubule cells: 15.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 67.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 67.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060640, HPA065661" Supported Supported Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 102: Non-specific - Mixed function" 27 Nucleoplasm "HPA060640: , HPA065661: " "unprognostic (3.91e-2)" "unprognostic (1.29e-1)" "unprognostic (2.84e-2)" "unprognostic (4.13e-1)" "unprognostic (2.74e-1)" "unprognostic (2.38e-2)" "unprognostic (1.93e-1)" "unprognostic (2.06e-3)" "unprognostic (3.58e-2)" "unprognostic (1.29e-1)" "potential prognostic favorable (9.68e-8)" "unprognostic (2.33e-3)" "unprognostic (7.24e-2)" "unprognostic (1.14e-1)" "unprognostic (3.57e-2)" "unprognostic (6.66e-2)" "unprognostic (7.29e-3)" "unprognostic (2.14e-1)" "unprognostic (1.78e-1)" "unprognostic (6.36e-2)" "unprognostic (4.04e-1)" "unprognostic (3.37e-1)" "unprognostic (9.18e-2)" "unprognostic (2.67e-1)" "unprognostic (9.83e-2)" "unprognostic (2.07e-1)" "unprognostic (9.88e-2)" "unprognostic (1.52e-1)" "unprognostic (8.40e-2)" "unprognostic (1.69e-1)" "unprognostic (2.78e-1)" TOR1A "DQ2, DYT1" ENSG00000136827 "Torsin family 1 member A" O14656 9 129812942-129824244 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Chaperone, Hydrolase" "Disease variant, Dystonia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 81.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012473, HPA051195" Approved Supported "Nuclear membrane,Vesicles" "Intracellular and membrane" Enzyme NA NA 20000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 76: Non-specific - Metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 31 "Nuclear membrane, Vesicles" "CAB012473: , HPA051195: " "potential prognostic unfavorable (2.10e-4)" "unprognostic (1.14e-2)" "unprognostic (7.75e-2)" "unprognostic (4.31e-2)" "unprognostic (1.48e-1)" "unprognostic (5.91e-3)" "unprognostic (9.35e-2)" "unprognostic (4.46e-2)" "unprognostic (5.99e-3)" "unprognostic (1.35e-1)" "potential prognostic favorable (3.12e-5)" "unprognostic (7.09e-2)" "unprognostic (1.88e-1)" "unprognostic (9.57e-2)" "unprognostic (1.15e-1)" "unprognostic (2.03e-3)" "unprognostic (1.18e-2)" "unprognostic (4.38e-2)" "unprognostic (2.28e-1)" "unprognostic (1.22e-1)" "unprognostic (1.07e-1)" "unprognostic (1.82e-1)" "unprognostic (7.88e-2)" "unprognostic (1.65e-1)" "unprognostic (1.68e-1)" "unprognostic (9.03e-2)" "unprognostic (2.50e-1)" "unprognostic (8.54e-3)" "unprognostic (1.60e-1)" "unprognostic (8.40e-2)" "unprognostic (5.30e-2)" TOR1AIP1 "FLJ13142, LAP1, LAP1B, LAP1C" ENSG00000143337 "Torsin 1A interacting protein 1" Q5JTV8 1 179882042-179920077 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 386.9;Late spermatids: 288.5;Neutrophil progenitors: 288.8;Neutrophils: 262.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Fibroblasts, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047151, HPA050546, HPA070991" Enhanced Supported "Nuclear membrane" NA NA 11000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 39 "Nuclear membrane" "HPA047151: , HPA050546: , HPA070991: " "unprognostic (6.61e-3)" "unprognostic (1.58e-1)" "unprognostic (1.61e-1)" "unprognostic (8.17e-3)" "unprognostic (2.05e-1)" "unprognostic (7.61e-3)" "unprognostic (1.30e-1)" "unprognostic (3.18e-2)" "unprognostic (1.66e-1)" "unprognostic (1.74e-1)" "potential prognostic favorable (7.59e-6)" "unprognostic (1.20e-3)" "unprognostic (9.11e-2)" "unprognostic (2.93e-1)" "unprognostic (3.16e-1)" "unprognostic (3.12e-1)" "unprognostic (7.81e-2)" "unprognostic (1.23e-3)" "unprognostic (1.76e-1)" "unprognostic (3.08e-2)" "unprognostic (6.97e-3)" "unprognostic (1.48e-1)" "unprognostic (1.74e-1)" "unprognostic (1.12e-1)" "unprognostic (1.78e-3)" "unprognostic (1.81e-2)" "unprognostic (1.80e-2)" "unprognostic (2.86e-3)" "unprognostic (2.89e-2)" "unprognostic (5.81e-2)" "unprognostic (1.86e-1)" TOR1AIP2 "IFRG15, LULL1, NET9" ENSG00000169905 "Torsin 1A interacting protein 2" "Q8NFQ8, Q9H496" 1 179839967-179877803 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Enterocytes: 356.0;Esophageal apical cells: 438.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051849, HPA058348, HPA070542" Uncertain Enhanced "Endoplasmic reticulum" NA NA 8600 "Cluster 32: Basophils - Transcription" "Cluster 76: Non-specific - Metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 93: Hepatocytes - Bile production & excretion" 26 "Endoplasmic reticulum" "HPA051849: , HPA058348: , HPA070542: " "unprognostic (2.00e-1)" "unprognostic (2.29e-1)" "unprognostic (5.64e-2)" "unprognostic (6.76e-3)" "unprognostic (2.34e-2)" "unprognostic (3.07e-2)" "unprognostic (3.14e-1)" "unprognostic (9.69e-3)" "unprognostic (1.37e-1)" "unprognostic (1.04e-2)" "unprognostic (6.36e-3)" "unprognostic (4.86e-3)" "unprognostic (7.59e-2)" "unprognostic (8.39e-2)" "unprognostic (1.12e-2)" "unprognostic (6.06e-2)" "unprognostic (9.58e-2)" "unprognostic (5.74e-2)" "unprognostic (1.26e-1)" "unprognostic (4.05e-1)" "unprognostic (9.85e-3)" "unprognostic (1.16e-2)" "unprognostic (5.48e-2)" "unprognostic (8.21e-2)" "unprognostic (5.88e-2)" "unprognostic (1.49e-1)" "unprognostic (6.35e-2)" "unprognostic (2.13e-1)" "unprognostic (1.45e-1)" "unprognostic (1.22e-2)" "unprognostic (3.44e-1)" TOR1B "DQ1, MGC4386" ENSG00000136816 "Torsin family 1 member B" O14657 9 129803157-129811281 "Predicted intracellular proteins, Predicted membrane proteins" "Chaperone, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 78.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013403, HPA013697, CAB022709" Approved Uncertain "Nuclear speckles,Cytosol" NA NA 84000 "Cluster 28: Neutrophils - Unknown function" "Cluster 17: Intestine - Digestion" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 32 "Nuclear speckles" Cytosol "CAB022709: , HPA013403: , HPA013697: " "unprognostic (8.33e-2)" "potential prognostic unfavorable (6.46e-4)" "unprognostic (2.86e-1)" "unprognostic (6.76e-3)" "unprognostic (1.46e-1)" "unprognostic (1.95e-1)" "unprognostic (2.17e-1)" "unprognostic (1.19e-1)" "unprognostic (9.45e-2)" "unprognostic (2.03e-1)" "potential prognostic favorable (3.59e-4)" "unprognostic (4.80e-2)" "unprognostic (1.08e-2)" "unprognostic (1.30e-1)" "unprognostic (3.04e-2)" "unprognostic (7.05e-2)" "unprognostic (1.25e-2)" "unprognostic (1.47e-1)" "unprognostic (1.41e-1)" "unprognostic (1.47e-2)" "unprognostic (6.47e-2)" "unprognostic (4.06e-1)" "unprognostic (1.86e-1)" "unprognostic (1.73e-2)" "unprognostic (3.46e-2)" "unprognostic (9.04e-2)" "unprognostic (1.13e-1)" "unprognostic (2.20e-1)" "unprognostic (3.96e-1)" "unprognostic (2.41e-3)" "unprognostic (3.93e-1)" TOR2A "FLJ14771, TORP1" ENSG00000160404 "Torsin family 2 member A" "Q5JU69, Q8N2E6" 9 127731524-127735313 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 45.5;Early spermatids: 69.8;Esophageal apical cells: 43.3;Extravillous trophoblasts: 49.4;Hofbauer cells: 76.9;Late primary spermatocytes: 82.9;Syncytiotrophoblasts: 60.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Macrophages, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071229 Approved Uncertain "Endoplasmic reticulum,Plasma membrane" "Secreted to blood" Hormone NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 23: Choroid plexus - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 5 "Endoplasmic reticulum, Plasma membrane" "HPA071229: " "unprognostic (1.71e-1)" "unprognostic (2.52e-2)" "unprognostic (2.04e-1)" "unprognostic (1.43e-1)" "unprognostic (3.69e-1)" "unprognostic (1.65e-1)" "unprognostic (2.51e-2)" "potential prognostic favorable (8.34e-6)" "unprognostic (7.79e-2)" "unprognostic (3.82e-1)" "unprognostic (1.35e-2)" "unprognostic (1.07e-1)" "unprognostic (6.04e-2)" "potential prognostic unfavorable (9.57e-4)" "unprognostic (1.11e-1)" "unprognostic (2.55e-1)" "unprognostic (1.15e-2)" "unprognostic (2.76e-1)" "unprognostic (6.14e-2)" "unprognostic (8.23e-2)" "unprognostic (5.56e-2)" "unprognostic (9.69e-3)" "unprognostic (4.78e-2)" "unprognostic (3.76e-2)" "unprognostic (2.85e-1)" "unprognostic (2.15e-2)" "unprognostic (1.92e-1)" "unprognostic (9.34e-2)" "unprognostic (2.70e-1)" "unprognostic (7.45e-2)" "unprognostic (1.64e-2)" TOR3A "ADIR, ADIR2, FLJ22345" ENSG00000186283 "Torsin family 3 member A" Q9H497 1 179082070-179098023 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "cDC: 84.2;Extravillous trophoblasts: 71.5;Oocytes: 161.2;Plasma cells: 168.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pituitary gland - Undifferentiated cells (Pituitary gland)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028766 Approved "Intracellular and membrane" "No annotated function" NA Yes "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 21: Non-specific - Metabolism" "Cluster 20: Myeloma - Immune response" "Cluster 44: Plasma cells - Antibody production & secretion" 25 "HPA028766: " "unprognostic (3.93e-1)" "unprognostic (1.84e-1)" "unprognostic (3.26e-2)" "unprognostic (2.05e-1)" "unprognostic (2.44e-1)" "unprognostic (1.20e-1)" "unprognostic (9.00e-2)" "unprognostic (3.69e-2)" "unprognostic (3.19e-1)" "unprognostic (3.50e-2)" "validated prognostic unfavorable (2.36e-5)" "validated prognostic unfavorable (3.13e-4)" "unprognostic (1.15e-3)" "unprognostic (1.29e-2)" "unprognostic (3.61e-3)" "unprognostic (1.14e-1)" "unprognostic (8.27e-2)" "unprognostic (3.91e-2)" "unprognostic (2.93e-2)" "unprognostic (1.97e-1)" "unprognostic (5.28e-2)" "unprognostic (3.01e-1)" "unprognostic (8.06e-2)" "unprognostic (2.93e-1)" "unprognostic (7.51e-2)" "unprognostic (2.76e-2)" "unprognostic (6.42e-3)" "unprognostic (1.48e-1)" "unprognostic (8.52e-2)" "unprognostic (1.67e-1)" "unprognostic (2.18e-2)" TOR4A "C9orf167, FLJ20245" ENSG00000198113 "Torsin family 4 member A" Q9NXH8 9 137277726-137282641 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Colonocytes: 34.5;Enteric stem cells: 27.3;Enteric transient amplifying cells: 33.6;Esophageal apical cells: 30.7;Foveolar cells: 26.6;Gastric progenitor cells: 25.6;monocytes: 25.5;Platelets: 36.7" "Group enriched" "Detected in some" 6 "central nervous system macrophage: 8.3;endothelial cell: 9.8;leukocyte: 6.9;pericyte: 13.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044913 Enhanced Approved Nucleoplasm NA NA 29000 "Cluster 22: Eosinophils - Transcription" "Cluster 5: Spleen - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 6 Nucleoplasm "HPA044913: " "unprognostic (4.68e-2)" "unprognostic (2.15e-1)" "unprognostic (3.37e-3)" "unprognostic (1.89e-1)" "unprognostic (1.73e-1)" "unprognostic (1.33e-2)" "unprognostic (2.66e-1)" "unprognostic (8.61e-2)" "unprognostic (6.95e-3)" "potential prognostic favorable (8.30e-4)" "unprognostic (2.19e-1)" "unprognostic (1.63e-2)" "unprognostic (1.07e-3)" "unprognostic (1.78e-3)" "unprognostic (8.65e-2)" "unprognostic (1.68e-3)" "unprognostic (1.10e-1)" "unprognostic (1.69e-1)" "unprognostic (1.22e-1)" "unprognostic (5.02e-3)" "unprognostic (4.08e-1)" "unprognostic (1.80e-1)" "unprognostic (2.74e-1)" "unprognostic (1.00e-1)" "unprognostic (1.27e-1)" "unprognostic (1.02e-2)" "unprognostic (2.16e-3)" "unprognostic (9.37e-2)" "unprognostic (1.58e-1)" TOX "KIAA0808, TOX1" ENSG00000198846 "Thymocyte selection associated high mobility group box" O94900 8 58805412-59119147 "Predicted intracellular proteins, Transcription factors" "Neurogenesis, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 48.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 427.2;Bergmann glia: 463.0;Gonadotrophs: 772.3;Innate lymphoid cells: 679.8;Neuroendocrine cells: 698.2;NK-cells: 577.3;Oligodendrocyte progenitor cells: 642.6;Renal collecting duct principal cells: 603.5;Renal connecting tubule cells: 755.2;Sertoli cells: 787.2;T-cells: 466.3;Thymocytes: 779.2" "Cell type enhanced" "Detected in many" "mammillary body: 1804.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 36.7" "Group enriched" "Detected in many" 5 "granulocytes: 21.6;NK-cells: 18.4;T-cells: 36.7" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Lung - Alveolar cells type 2, Pituitary gland - Gonadotropes, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA018322, HPA073241" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 59: Leukemia - T-cell receptor" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" 5 "Nucleoplasm, Nucleoli fibrillar center" "HPA018322: , HPA073241: " "unprognostic (7.25e-2)" "unprognostic (2.01e-3)" "unprognostic (5.81e-2)" "potential prognostic favorable (1.87e-4)" "unprognostic (4.32e-2)" "unprognostic (6.16e-2)" "unprognostic (5.73e-2)" "unprognostic (1.23e-2)" "unprognostic (2.52e-1)" "unprognostic (1.92e-1)" "unprognostic (4.66e-2)" "unprognostic (1.93e-3)" "unprognostic (4.85e-2)" "unprognostic (1.34e-3)" "unprognostic (4.11e-2)" "unprognostic (1.18e-1)" "unprognostic (3.10e-1)" "unprognostic (6.92e-3)" "unprognostic (9.18e-2)" "unprognostic (2.88e-3)" "unprognostic (2.15e-1)" "unprognostic (1.48e-1)" "unprognostic (3.08e-1)" "unprognostic (5.32e-3)" "unprognostic (6.93e-2)" "unprognostic (5.61e-2)" "unprognostic (1.08e-1)" "unprognostic (3.94e-2)" "unprognostic (4.84e-2)" TOX2 "C20orf100, dJ1108D11.2, GCX-1" ENSG00000124191 "TOX high mobility group box family member 2" Q96NM4 20 43914852-44069616 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 46.7" "Cell type enhanced" "Detected in many" "Corticotrophs: 266.3;Innate lymphoid cells: 252.2;Lactotrophs: 83.5;Oligodendrocyte progenitor cells: 70.7;Oocytes: 82.9;Sertoli cells: 175.9;Thymocytes: 71.1;Thyrotrophs: 130.7;Vascular endothelial cells: 60.7" "Cell type enhanced" "Detected in all" "LAMP5-LHX6 and Chandelier: 212.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 6.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells, Liver - Vascular endothelial cells, Pituitary gland - Corticotropes, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA049900, HPA058396" Approved Supported Nucleoplasm NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 72: Neuronal - Signal transduction" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" Nucleoplasm "HPA049900: , HPA058396: " "unprognostic (2.89e-2)" "unprognostic (7.38e-2)" "unprognostic (6.48e-2)" "unprognostic (1.90e-1)" "unprognostic (2.09e-2)" "unprognostic (2.95e-1)" "unprognostic (1.31e-1)" "unprognostic (1.95e-1)" "unprognostic (1.61e-1)" "unprognostic (3.59e-3)" "unprognostic (1.08e-3)" "potential prognostic favorable (1.93e-4)" "potential prognostic unfavorable (6.40e-7)" "unprognostic (2.26e-3)" "unprognostic (1.33e-1)" "unprognostic (2.21e-1)" "unprognostic (3.27e-1)" "unprognostic (1.04e-1)" "unprognostic (4.55e-2)" "unprognostic (5.95e-2)" "unprognostic (1.29e-1)" "unprognostic (1.04e-1)" "potential prognostic unfavorable (3.41e-5)" "unprognostic (1.04e-2)" "unprognostic (6.15e-2)" "unprognostic (1.00e-1)" "unprognostic (8.33e-2)" "unprognostic (1.60e-1)" "unprognostic (3.40e-2)" "unprognostic (1.35e-1)" "unprognostic (1.26e-1)" TOX3 "CAGF9, TNRC9" ENSG00000103460 "TOX high mobility group box family member 3" O15405 16 52436417-52547802 "Predicted intracellular proteins, Transcription factors" "Apoptosis, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 16.8;retina: 16.4;stomach 1: 19.1" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 546.1;Foveolar cells: 244.0;Mucous neck cells: 198.9;Müller glia: 321.6;Renal collecting duct intercalated cells: 368.0;Renal collecting duct principal cells: 484.7;Renal connecting tubule cells: 913.6;Respiratory secretory cells: 200.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Breast - Breast glandular cells, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA040240, HPA040376" Enhanced Enhanced Nucleoplasm,Cytosol NA NA "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 27: Non-specific - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" Nucleoplasm Cytosol "HPA040240: , HPA040376: " "unprognostic (1.58e-1)" "unprognostic (6.19e-2)" "unprognostic (3.28e-2)" "unprognostic (2.71e-2)" "unprognostic (4.28e-1)" "unprognostic (9.45e-2)" "unprognostic (1.41e-1)" "potential prognostic favorable (2.66e-4)" "unprognostic (2.52e-1)" "validated prognostic favorable (9.38e-10)" "validated prognostic favorable (1.53e-4)" "unprognostic (2.67e-1)" "unprognostic (6.88e-3)" "unprognostic (5.66e-2)" "unprognostic (1.17e-1)" "unprognostic (1.05e-1)" "unprognostic (1.73e-1)" "unprognostic (1.35e-1)" "unprognostic (4.69e-2)" "unprognostic (1.41e-1)" "unprognostic (1.02e-1)" "unprognostic (2.63e-2)" "unprognostic (6.65e-3)" "unprognostic (2.58e-1)" "unprognostic (3.01e-2)" "unprognostic (1.61e-1)" "unprognostic (1.70e-1)" TOX4 "C14orf92, KIAA0737, LCP1" ENSG00000092203 "TOX high mobility group box family member 4" O94842 14 21476597-21499175 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 241.9;Syncytiotrophoblasts: 379.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001899, HPA017880, HPA027551" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 41: Basophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 25 Nucleoplasm Vesicles "HPA001899: , HPA017880: , HPA027551: " "unprognostic (3.03e-2)" "unprognostic (3.79e-2)" "unprognostic (6.60e-3)" "unprognostic (2.48e-2)" "unprognostic (6.33e-3)" "unprognostic (1.26e-1)" "unprognostic (4.23e-1)" "unprognostic (5.03e-2)" "unprognostic (1.14e-1)" "unprognostic (3.85e-3)" "potential prognostic favorable (6.51e-6)" "unprognostic (1.20e-3)" "unprognostic (4.19e-2)" "potential prognostic unfavorable (4.10e-4)" "unprognostic (1.28e-3)" "unprognostic (3.26e-2)" "unprognostic (8.34e-3)" "unprognostic (1.64e-1)" "unprognostic (2.44e-1)" "unprognostic (1.93e-2)" "unprognostic (9.81e-2)" "unprognostic (4.95e-2)" "unprognostic (2.29e-2)" "unprognostic (3.00e-1)" "unprognostic (2.51e-1)" "unprognostic (2.91e-2)" "unprognostic (1.49e-1)" "unprognostic (3.60e-2)" "unprognostic (1.49e-1)" "unprognostic (1.52e-1)" "unprognostic (1.01e-2)" TP53 "LFS1, p53" ENSG00000141510 "Tumor protein p53" P04637 17 7661779-7687538 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors, Transporters" "Apoptosis, Biological rhythms, Cell cycle, Host-virus interaction, Necrosis, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Li-Fraumeni syndrome, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cell type enhanced" "Detected in all" "astrocyte: 44.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002973, CAB039238, CAB039239, HPA051244, HPA063532, CAB072876" Enhanced Enhanced Nucleoplasm,Vesicles,Cytosol Yes No "Cluster 13: Non-specific - Mitochondria" "Cluster 54: Non-specific - Ribosome" "Cluster 44: Non-specific - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 65: Non-specific - Cell growth & division" 998 Nucleoplasm "Vesicles, Cytosol" "CAB002973: , CAB039238: , CAB039239: , CAB072876: , HPA051244: , HPA063532: " "unprognostic (5.89e-2)" "unprognostic (2.13e-3)" "potential prognostic favorable (5.06e-4)" "unprognostic (2.07e-1)" "unprognostic (4.64e-2)" "potential prognostic favorable (5.72e-4)" "unprognostic (8.05e-2)" "unprognostic (1.85e-1)" "unprognostic (8.66e-2)" "unprognostic (1.02e-1)" "unprognostic (3.74e-2)" "unprognostic (8.43e-3)" "unprognostic (3.70e-2)" "unprognostic (1.11e-2)" "unprognostic (3.46e-2)" "unprognostic (3.42e-1)" "unprognostic (2.94e-2)" "unprognostic (1.51e-1)" "unprognostic (6.21e-2)" "unprognostic (4.78e-2)" "unprognostic (5.54e-2)" "unprognostic (6.70e-2)" "unprognostic (1.23e-1)" "unprognostic (1.28e-3)" "unprognostic (1.50e-2)" "unprognostic (1.07e-1)" "unprognostic (4.18e-3)" "unprognostic (8.20e-2)" "unprognostic (3.49e-1)" "unprognostic (1.45e-2)" "unprognostic (2.07e-2)" TP53AIP1 p53AIP1 ENSG00000120471 "Tumor protein p53 regulated apoptosis inducing protein 1" Q9HCN2 11 128934731-128943399 "Predicted intracellular proteins" Apoptosis "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "cervix: 14.7;esophagus: 24.8;lymphoid tissue: 27.6;skin 1: 19.2;vagina: 13.8" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 56.4;Breast myoepithelial cells: 76.6;Endometrial ciliated cells: 38.5;Epididymal basal cells: 30.2;Epididymal efferent duct ciliated cells: 114.2;Esophageal basal cells: 158.2;Esophageal suprabasal cells: 28.5;Fallopian tube ciliated cells: 19.7;Suprabasal keratinocytes: 28.2" "Cell type enriched" "Detected in some" 4 "ependymal cell: 9.2" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 14.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "head and neck cancer: 2.9" "Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary gland basal cells" "HPA044300, HPA048797" Uncertain NA NA "Cluster 49: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 26: Keratinocytes - Keratinization" "HPA044300: , HPA048797: " "unprognostic (3.31e-2)" "unprognostic (2.00e-1)" "unprognostic (1.53e-1)" "unprognostic (5.97e-2)" "unprognostic (9.91e-2)" "unprognostic (1.63e-1)" "unprognostic (1.22e-1)" "unprognostic (1.55e-1)" "unprognostic (3.51e-1)" "unprognostic (3.13e-1)" "unprognostic (1.88e-1)" TP53BP1 "53BP1, p202, TDRD30" ENSG00000067369 "Tumor protein p53 binding protein 1" Q12888 15 43403061-43510728 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Lactotrophs: 329.4;Somatotrophs: 324.5;Thyrotrophs: 300.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004083, HPA008788, HPA022133, CAB079980" Supported Enhanced "Nucleoplasm,Nuclear bodies" No No 5500 "Cluster 5: Non-specific - Cell proliferation" "Cluster 65: Brain - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 58: Non-specific - Nuclear processes" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 151 "Nuclear bodies" Nucleoplasm "CAB004083: , CAB079980: , HPA008788: , HPA022133: " "unprognostic (6.68e-3)" "unprognostic (1.32e-1)" "unprognostic (9.21e-2)" "unprognostic (5.88e-3)" "unprognostic (8.25e-2)" "unprognostic (2.08e-1)" "unprognostic (5.99e-3)" "potential prognostic favorable (1.49e-4)" "unprognostic (2.17e-1)" "unprognostic (3.35e-2)" "unprognostic (1.07e-2)" "unprognostic (3.65e-2)" "unprognostic (1.97e-1)" "unprognostic (7.03e-2)" "unprognostic (1.52e-1)" "unprognostic (4.08e-1)" "unprognostic (1.04e-1)" "unprognostic (3.18e-1)" "unprognostic (4.69e-2)" "unprognostic (2.49e-2)" "unprognostic (2.92e-1)" "unprognostic (4.40e-1)" "unprognostic (4.44e-3)" "unprognostic (2.00e-1)" "unprognostic (5.80e-2)" "unprognostic (2.58e-1)" "unprognostic (2.85e-1)" "unprognostic (2.63e-1)" "unprognostic (1.89e-1)" "unprognostic (3.14e-1)" "unprognostic (1.04e-1)" TP53BP2 "53BP2, ASPP2, PPP1R13A" ENSG00000143514 "Tumor protein p53 binding protein 2" Q13625 1 223779893-223845954 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 579.5;Endometrial luminal cells: 345.3;Ocular epithelial cells: 352.5" "Cell type enhanced" "Detected in all" "astrocyte: 121.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021603, HPA050429" Supported Enhanced "Cell Junctions,Cytosol" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 78: Brain - Neuronal signaling" "Cluster 39: Astrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 51: Secretory epithelial cells - Mixed function" 66 "Cell Junctions, Cytosol" "HPA021603: , HPA050429: " "unprognostic (2.06e-2)" "unprognostic (1.45e-1)" "unprognostic (8.44e-3)" "unprognostic (6.64e-2)" "unprognostic (1.07e-1)" "unprognostic (1.16e-2)" "unprognostic (7.91e-3)" "unprognostic (3.22e-1)" "unprognostic (2.06e-1)" "unprognostic (5.95e-3)" "unprognostic (2.43e-3)" "unprognostic (9.02e-2)" "unprognostic (1.06e-1)" "unprognostic (4.61e-2)" "unprognostic (2.65e-1)" "unprognostic (1.09e-1)" "potential prognostic unfavorable (2.79e-4)" "unprognostic (1.54e-1)" "unprognostic (9.05e-2)" "unprognostic (1.79e-2)" "unprognostic (9.78e-2)" "unprognostic (2.76e-2)" "unprognostic (7.30e-3)" "unprognostic (1.87e-1)" "unprognostic (5.76e-2)" "unprognostic (3.82e-2)" "unprognostic (7.93e-2)" "unprognostic (2.26e-1)" "unprognostic (1.54e-1)" "unprognostic (2.11e-1)" "unprognostic (3.14e-1)" TP53I11 PIG11 ENSG00000175274 "Tumor protein p53 inducible protein 11" O14683 11 44885903-44951306 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Late spermatids: 958.0" "Cell type enhanced" "Detected in many" "deep-layer near-projecting: 53.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 41.4" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059727, HPA061276" Uncertain Approved "Endoplasmic reticulum,Golgi apparatus,Acrosome,Principal piece" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 2 "Endoplasmic reticulum, Golgi apparatus" "Acrosome, Principal piece" "HPA059727: , HPA061276: " "unprognostic (7.54e-2)" "potential prognostic unfavorable (2.14e-4)" "unprognostic (1.03e-1)" "unprognostic (2.22e-1)" "unprognostic (6.96e-2)" "unprognostic (7.43e-3)" "unprognostic (1.66e-1)" "unprognostic (9.61e-2)" "unprognostic (1.68e-1)" "unprognostic (4.22e-2)" "unprognostic (3.05e-3)" "potential prognostic favorable (4.43e-5)" "unprognostic (8.04e-2)" "unprognostic (1.90e-2)" "unprognostic (2.26e-1)" "unprognostic (2.34e-1)" "unprognostic (7.42e-2)" "unprognostic (9.12e-2)" "unprognostic (1.03e-1)" "unprognostic (5.12e-2)" "unprognostic (4.58e-2)" "unprognostic (9.25e-2)" "unprognostic (1.35e-1)" "unprognostic (1.99e-1)" "unprognostic (6.50e-2)" "unprognostic (3.65e-1)" "unprognostic (2.62e-3)" "unprognostic (4.42e-2)" "unprognostic (2.43e-1)" "unprognostic (9.60e-2)" "unprognostic (1.34e-1)" TP53I13 DSCP1 ENSG00000167543 "Tumor protein p53 inducible protein 13" Q8NBR0 17 29566052-29573157 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 33.7;Late primary spermatocytes: 31.8;pDCs: 23.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 111.2" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Pituitary gland - Thyrotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 70: Non-specific - Protein processing" "Cluster 12: Non-specific - Vasculature" "Cluster 35: RS4;11 - Unknown function" "Cluster 67: Plasma cells - Plasma cell differentiation" 1 "unprognostic (2.26e-1)" "unprognostic (3.96e-2)" "unprognostic (1.37e-1)" "unprognostic (1.01e-2)" "unprognostic (5.62e-2)" "unprognostic (2.97e-1)" "unprognostic (1.28e-2)" "unprognostic (1.16e-1)" "unprognostic (4.16e-2)" "unprognostic (9.04e-2)" "potential prognostic unfavorable (6.71e-7)" "unprognostic (6.08e-2)" "unprognostic (1.57e-1)" "unprognostic (1.39e-1)" "unprognostic (9.33e-2)" "unprognostic (2.83e-1)" "unprognostic (3.07e-1)" "unprognostic (8.89e-2)" "unprognostic (1.08e-1)" "unprognostic (4.89e-2)" "unprognostic (5.12e-3)" "potential prognostic favorable (5.18e-5)" "unprognostic (4.03e-1)" "unprognostic (2.81e-1)" "unprognostic (1.09e-1)" "unprognostic (2.93e-3)" "unprognostic (1.67e-2)" "unprognostic (1.68e-1)" "unprognostic (1.23e-1)" "unprognostic (1.58e-1)" "unprognostic (6.19e-2)" TP53I3 PIG3 ENSG00000115129 "Tumor protein p53 inducible protein 3" Q53FA7 2 24077433-24085861 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 121.5" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 259.2;Enterocytes: 198.9;Esophageal apical cells: 897.4;Esophageal suprabasal cells: 220.3;Late primary spermatocytes: 176.1;Late spermatids: 296.3;Respiratory ionocytes: 170.2" "Cell type enhanced" "Detected in many" "Bergmann glia: 15.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "CAB017479, HPA022012, HPA028742" Enhanced Supported Vesicles NA NA 150000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 3 Vesicles "CAB017479: , HPA022012: , HPA028742: " "unprognostic (5.14e-2)" "unprognostic (8.83e-2)" "unprognostic (3.54e-2)" "unprognostic (6.39e-3)" "unprognostic (1.67e-2)" "unprognostic (9.75e-2)" "unprognostic (2.27e-1)" "unprognostic (1.58e-2)" "unprognostic (3.74e-1)" "unprognostic (3.16e-1)" "unprognostic (1.23e-3)" "unprognostic (1.13e-1)" "unprognostic (1.34e-3)" "unprognostic (3.01e-2)" "unprognostic (1.17e-2)" "potential prognostic unfavorable (3.32e-4)" "unprognostic (3.39e-1)" "unprognostic (1.19e-1)" "unprognostic (7.55e-2)" "unprognostic (1.20e-1)" "unprognostic (1.67e-1)" "unprognostic (3.66e-3)" "unprognostic (7.76e-2)" "unprognostic (1.23e-1)" "unprognostic (4.24e-3)" "unprognostic (2.40e-2)" "unprognostic (3.14e-2)" "unprognostic (6.01e-2)" "unprognostic (1.15e-1)" "unprognostic (2.16e-2)" "unprognostic (1.45e-2)" TP53INP1 "DKFZp434M1317, FLJ22139, P53DINP1, SIP, Teap, TP53INP1A, TP53INP1B" ENSG00000164938 "Tumor protein p53 inducible nuclear protein 1" Q96A56 8 94925972-94949378 "Predicted intracellular proteins" "Apoptosis, Autophagy, Transcription, Transcription regulation" "Activator, Antioxidant" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 95.3" "Cell type enhanced" "Detected in many" "B-cells: 198.6;Hepatocytes: 229.7;Neutrophils: 150.4;Pancreatic acinar cells: 141.2;Plasma cells: 471.9;Thymocytes: 283.7" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 51.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 54.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 54.8" "Group enriched" "Detected in all" 4 "Myeloma: 94.8;prostate cancer: 61.5;testis cancer: 35.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005856 Uncertain Supported Cytosol NA NA "Cluster 32: Basophils - Transcription" "Cluster 70: Non-specific - Protein processing" "Cluster 6: Non-specific - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 44: Plasma cells - Antibody production & secretion" 16 Cytosol "HPA005856: " "potential prognostic favorable (3.98e-4)" "unprognostic (4.65e-2)" "unprognostic (2.88e-1)" "unprognostic (1.03e-1)" "unprognostic (3.15e-1)" "unprognostic (1.52e-1)" "unprognostic (9.39e-2)" "unprognostic (3.06e-1)" "potential prognostic favorable (2.45e-4)" "unprognostic (4.98e-2)" "unprognostic (3.32e-1)" "potential prognostic favorable (1.13e-4)" "unprognostic (8.75e-2)" "unprognostic (1.23e-1)" "unprognostic (5.68e-2)" "unprognostic (2.19e-3)" "unprognostic (7.21e-2)" "unprognostic (2.14e-1)" "unprognostic (1.07e-1)" "unprognostic (3.40e-2)" "unprognostic (1.83e-2)" "unprognostic (6.34e-2)" "unprognostic (1.26e-1)" "unprognostic (2.51e-2)" "unprognostic (4.26e-2)" "unprognostic (1.44e-3)" "unprognostic (2.47e-2)" "unprognostic (1.45e-1)" "unprognostic (3.23e-1)" "unprognostic (9.75e-2)" "unprognostic (4.24e-2)" TP53INP2 "C20orf110, dJ1181N3.1, DKFZp434B2411, DKFZp434O0827, DOR, FLJ21759, FLJ23500, PINH" ENSG00000078804 "Tumor protein p53 inducible nuclear protein 2" Q8IXH6 20 34704339-34713439 "Predicted intracellular proteins" "Autophagy, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 10 "brain: 888.0" "Cell type enhanced" "Detected in many" "Colonocytes: 117.1;Early spermatids: 260.9;Esophageal apical cells: 326.4;Late spermatids: 585.1;Neutrophils: 102.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "neutrophil: 2.7" "Lineage enriched" "Detected in single" 14 "granulocytes: 2.7" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Cardiomyocytes, Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 6: Non-specific - Immune response" "Cluster 27: Breast cancer - Unknown function" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 3 "unprognostic (4.74e-2)" "unprognostic (5.85e-2)" "unprognostic (3.43e-2)" "unprognostic (1.09e-1)" "unprognostic (9.07e-2)" "unprognostic (2.61e-1)" "unprognostic (1.44e-1)" "unprognostic (1.32e-2)" "unprognostic (2.84e-2)" "unprognostic (2.65e-1)" "validated prognostic favorable (1.21e-11)" "validated prognostic favorable (5.29e-5)" "potential prognostic favorable (8.08e-6)" "unprognostic (2.39e-1)" "unprognostic (1.28e-1)" "unprognostic (6.11e-2)" "unprognostic (2.50e-1)" "unprognostic (2.34e-1)" "unprognostic (1.48e-1)" "unprognostic (8.46e-2)" "unprognostic (2.74e-1)" "unprognostic (4.48e-2)" "unprognostic (6.18e-2)" "potential prognostic unfavorable (8.69e-4)" "unprognostic (1.20e-1)" "unprognostic (2.23e-1)" "unprognostic (2.21e-1)" "unprognostic (3.93e-2)" "unprognostic (3.85e-2)" "unprognostic (1.43e-3)" "unprognostic (3.94e-2)" TP53RK "BUD32, C20orf64, dJ101A2.2, Nori-2p, prpk, TPRKB" ENSG00000172315 "TP53 regulating kinase" Q96S44 20 46684365-46689444 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "Hydrolase, Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 215.3;Extravillous trophoblasts: 93.1;Late primary spermatocytes: 227.4;Syncytiotrophoblasts: 115.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004688, HPA015837, HPA075054" Approved NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 39: Testis - Nuclear processes" "Cluster 34: Non-specific - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 22 "CAB004688: , HPA015837: , HPA075054: " "unprognostic (9.25e-2)" "unprognostic (2.43e-2)" "unprognostic (1.24e-1)" "unprognostic (2.72e-3)" "unprognostic (2.49e-1)" "unprognostic (7.95e-2)" "unprognostic (2.62e-1)" "unprognostic (1.70e-1)" "unprognostic (7.09e-2)" "unprognostic (2.84e-1)" "unprognostic (8.22e-3)" "unprognostic (2.59e-1)" "unprognostic (1.09e-1)" "potential prognostic unfavorable (1.66e-5)" "unprognostic (2.08e-2)" "unprognostic (9.99e-2)" "unprognostic (3.38e-3)" "unprognostic (1.34e-1)" "unprognostic (8.83e-2)" "unprognostic (2.88e-1)" "potential prognostic unfavorable (1.18e-4)" "unprognostic (7.06e-3)" "unprognostic (4.51e-1)" "unprognostic (4.41e-2)" "unprognostic (1.03e-2)" "unprognostic (8.83e-2)" "unprognostic (2.05e-1)" "unprognostic (5.01e-2)" "unprognostic (1.78e-1)" "unprognostic (3.34e-2)" "unprognostic (6.32e-2)" TP53TG3 "P53TG3, TP53TG3A" ENSG00000183632 "TP53 target 3" Q9ULZ0 16 32673528-32676165 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 14 "epididymis: 6.5;testis: 3.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 1.3" "HPA047832, HPA060916" Approved "Centriolar satellite" NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Centriolar satellite" "HPA047832: , HPA060916: " TP53TG3B ENSG00000261509 "TP53 target 3B" Q9ULZ0 16 33360841-33363478 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 5 "epididymis: 4.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Skin Cutaneous Melanoma (TCGA): 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047832, HPA060916" Approved "Centriolar satellite" NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Centriolar satellite" "HPA047832: , HPA060916: " "unprognostic (2.45e-1)" "unprognostic (4.27e-3)" TP53TG3C ENSG00000205457 "TP53 target 3C" Q9ULZ0 16 33194226-33196858 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047832, HPA060916" Uncertain "Centriolar satellite" NA NA "Cluster 10: Ciliated cells - Ion channel activity" "Centriolar satellite" "HPA047832: , HPA060916: " "unprognostic (3.24e-1)" TP53TG3D ENSG00000205456 "TP53 target 3D" Q9ULZ0 16 32253286-32255928 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "epididymis: 4.0;testis: 4.3" "Cell type enhanced" "Detected in some" "Early primary spermatocytes: 20.2;Early spermatids: 72.1;Late primary spermatocytes: 61.4;Late spermatids: 17.7;Platelets: 8.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Ovary Serous Cystadenocarcinoma (TCGA): 1.0;Skin Cutaneous Melanoma (TCGA): 1.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 1.4" "Testis - Early spermatids" "HPA047832, HPA060916" Approved "Centriolar satellite" NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" "Centriolar satellite" "HPA047832: , HPA060916: " "unprognostic (3.01e-1)" "unprognostic (9.37e-2)" "unprognostic (8.57e-2)" TP53TG3E ENSG00000275034 "TP53 target 3 family member E" Q9ULZ0 16 33304306-33306945 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 13 "epididymis: 2.9;testis: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047832, HPA060916" Approved "Centriolar satellite" NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Centriolar satellite" "HPA047832: , HPA060916: " TP53TG3F ENSG00000278848 "TP53 target 3 family member F" Q9ULZ0 16 33459612-33462249 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 18 "epididymis: 9.9;testis: 4.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047832, HPA060916" Approved "Centriolar satellite" NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Centriolar satellite" "HPA047832: , HPA060916: " TP53TG5 "C20orf10, CLG01, dJ453C12.5" ENSG00000124251 "TP53 target 5" Q9Y2B4 20 45372557-45407889 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 16.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 144.7;Early spermatids: 1008.7;Epicardial cells: 145.5;Late spermatids: 326.1;Oligodendrocytes: 195.0" "Cell type enriched" "Detected in all" 4 "oligodendrocyte: 238.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Smooth muscle cells, Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA041979, HPA058510, HPA077455" Enhanced Supported "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes NA "Cluster 67: Testis - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 62: Non-specific - Plasma proteins" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 1 "Nucleoli, Nucleoli rim" "Mitotic chromosome" "HPA041979: , HPA058510: , HPA077455: " "unprognostic (1.83e-1)" "unprognostic (2.01e-2)" TP63 "EEC3, KET, NBP, OFC8, p40, p51, p53CP, p63, p73H, p73L, SHFM4, TP53CP, TP53L, TP73L" ENSG00000073282 "Tumor protein p63" Q9H3D4 3 189631389-189897276 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Apoptosis, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Disease variant, Ectodermal dysplasia, Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 65.3;skin 1: 129.6;vagina: 52.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 759.5;Basal prostatic cells: 387.2;Esophageal basal cells: 231.3;Medullary thymic epithelial cells: 254.4;Myonuclei: 1460.7;Papillary tip epithelial cells: 344.5;Respiratory basal cells: 414.7;Suprabasal keratinocytes: 528.3;Thymic myoid cells: 1309.3" "Group enriched" "Detected in many" 9 "ependymal cell: 95.5;fibroblast: 212.0;pericyte: 102.4" "Group enriched" "Detected in many" 15 "Bladder Urothelial Carcinoma (TCGA): 55.5;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 111.2;Head and Neck Squamous Cell Carcinoma (TCGA): 184.6;Lung Squamous Cell Carcinoma (TCGA): 172.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Esophageal cancer: 114.7;Gallbladder cancer: 194.8;head and neck cancer: 125.5" "Colon - Enteric glia cells, Lung - Respiratory ciliated cells, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other), Testis - Spermatogonia" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB000083, HPA006288, HPA006289, HPA007009, HPA007010" Enhanced Enhanced Nucleoplasm NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 58: Skin - Keratinization" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 49 Nucleoplasm "CAB000083: , HPA006288: , HPA006289: , HPA007009: , HPA007010: " "unprognostic (2.81e-1)" "potential prognostic favorable (5.55e-5)" "unprognostic (2.92e-1)" "unprognostic (1.62e-1)" "unprognostic (1.08e-1)" "unprognostic (2.48e-2)" "unprognostic (1.18e-1)" "unprognostic (2.92e-2)" "unprognostic (2.19e-1)" "unprognostic (4.93e-2)" "unprognostic (1.84e-2)" "unprognostic (5.08e-3)" "unprognostic (5.64e-3)" "unprognostic (3.31e-2)" "unprognostic (2.11e-1)" "unprognostic (7.46e-2)" "unprognostic (2.29e-2)" "unprognostic (1.22e-1)" "unprognostic (1.54e-1)" "unprognostic (1.40e-1)" "unprognostic (2.23e-1)" TP73 P73 ENSG00000078900 "Tumor protein p73" O15350 1 3652516-3736201 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Apoptosis, Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Activator, DNA-binding" "Ciliopathy, Disease variant, Lissencephaly, Primary ciliary dyskinesia, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.0;fallopian tube: 6.3;skin 1: 6.2" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 31.1;Early spermatids: 78.7;Endometrial ciliated cells: 55.0;Ependymal cells: 42.4;Epididymal efferent duct ciliated cells: 54.1;Fallopian tube ciliated cells: 57.0;Late spermatids: 35.9;Plasma cells: 22.5;Respiratory ciliated cells: 100.7;Respiratory deuterosomal cells: 108.8;Thymic myoid cells: 23.1" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 24.1;ependymal cell: 48.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Prostate - Prostate basal glandular cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "midbrain: 4.9" "CAB002514, CAB003022, HPA027314, HPA044516" Enhanced Supported "Nucleoplasm,Golgi apparatus,Vesicles,Plasma membrane,Cell Junctions,Centrosome,Basal body" NA Yes "Cluster 2: Non-specific - Mixed function" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" 76 Nucleoplasm "Golgi apparatus, Vesicles, Plasma membrane, Cell Junctions, Centrosome, Basal body" "CAB002514: , CAB003022: , HPA027314: , HPA044516: " "unprognostic (8.12e-3)" "unprognostic (4.73e-2)" "unprognostic (3.30e-1)" "unprognostic (3.98e-3)" "unprognostic (1.39e-1)" "unprognostic (1.89e-1)" "unprognostic (1.16e-1)" "unprognostic (7.16e-2)" "unprognostic (4.95e-3)" "unprognostic (1.25e-2)" "unprognostic (1.29e-1)" "unprognostic (4.65e-1)" "unprognostic (1.99e-2)" "unprognostic (2.36e-1)" "unprognostic (3.88e-3)" "unprognostic (1.29e-1)" "unprognostic (1.88e-2)" "potential prognostic favorable (8.29e-4)" "unprognostic (1.47e-1)" "unprognostic (4.65e-2)" "unprognostic (9.09e-2)" "unprognostic (1.40e-1)" TPBG "5T4, 5T4-AG" ENSG00000146242 "Trophoblast glycoprotein" Q13641 6 82363206-82367420 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 9.8;Brain inhibitory neurons: 18.0;Distal convoluted tubule cells: 4.9;Ependymal cells: 9.3;Loop of henle epithelial cells: 12.0;Other brain neurons: 13.0;Papillary tip epithelial cells: 32.8;Podocytes: 17.8;Renal collecting duct intercalated cells: 5.1;Renal collecting duct principal cells: 23.9;Renal connecting tubule cells: 4.9" "Cell type enhanced" "Detected in many" "lower rhombic lip: 47.8;medium spiny neuron: 49.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "MAIT T-cell: 1.4" "Lineage enriched" "Detected in single" 14 "T-cells: 1.4" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Breast - Breast glandular cells, Heart muscle - Fibroblasts, Lung - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA010554 Enhanced Approved Nucleoplasm NA NA 14000 "Cluster 74: Non-specific - Signal transduction" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Neurons - Synaptic function & neurogenesis" 3 Nucleoplasm "HPA010554: " "unprognostic (8.66e-3)" "unprognostic (1.45e-1)" "unprognostic (2.32e-1)" "unprognostic (5.99e-3)" "unprognostic (2.72e-2)" "unprognostic (5.29e-3)" "potential prognostic unfavorable (7.61e-4)" "unprognostic (2.84e-1)" "unprognostic (7.92e-3)" "unprognostic (3.18e-1)" "unprognostic (3.63e-1)" "unprognostic (3.16e-2)" "unprognostic (1.01e-1)" "unprognostic (1.70e-2)" "unprognostic (7.17e-2)" "unprognostic (2.50e-3)" "unprognostic (3.15e-3)" "unprognostic (1.72e-1)" "unprognostic (7.60e-2)" "unprognostic (1.20e-1)" "unprognostic (3.95e-1)" "unprognostic (4.41e-2)" "potential prognostic unfavorable (1.85e-4)" "unprognostic (3.69e-1)" "unprognostic (1.09e-2)" "unprognostic (2.34e-2)" "unprognostic (8.41e-2)" "unprognostic (2.91e-2)" "unprognostic (1.21e-1)" "unprognostic (1.12e-1)" "unprognostic (7.84e-2)" TPBGL ENSG00000261594 "Trophoblast glycoprotein like" P0DKB5 11 75240774-75243704 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.1;testis: 4.1" "Group enriched" "Detected in some" 4 "Epididymal efferent duct absorptive cells: 4.2;Melanocytes: 4.2;Müller glia: 11.2;Retinal bipolar cells: 14.4" "Cell type enhanced" "Detected in many" "LAMP5-LHX6 and Chandelier: 5.4" "Cancer enhanced" "Detected in some" "Ovary Serous Cystadenocarcinoma (TCGA): 6.1" "Region enhanced" "Detected in many" "medulla oblongata: 25.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Neuroblastoma: 2.8;skin cancer: 2.3" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in many" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "unprognostic (4.02e-1)" "unprognostic (5.29e-2)" "unprognostic (1.32e-1)" "unprognostic (7.32e-2)" "unprognostic (1.08e-1)" "unprognostic (7.18e-3)" TPCN1 "FLJ20612, KIAA1169, TPC1" ENSG00000186815 "Two pore segment channel 1" Q9ULQ1 12 113221050-113298585 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 304.4;Proximal tubule cells: 486.8;Renal collecting duct principal cells: 318.8;Urothelial cells: 304.8" "Cell type enhanced" "Detected in all" "fibroblast: 439.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039757 Approved NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 51: Secretory epithelial cells - Mixed function" 4 "HPA039757: " "unprognostic (1.21e-2)" "unprognostic (5.17e-3)" "unprognostic (4.94e-2)" "unprognostic (2.13e-3)" "unprognostic (5.77e-2)" "unprognostic (6.04e-2)" "unprognostic (1.83e-1)" "unprognostic (1.03e-1)" "unprognostic (4.13e-2)" "unprognostic (1.75e-3)" "unprognostic (6.52e-3)" "unprognostic (4.45e-1)" "potential prognostic favorable (3.64e-4)" "potential prognostic unfavorable (3.49e-4)" "unprognostic (1.58e-1)" "unprognostic (2.45e-1)" "potential prognostic unfavorable (5.13e-4)" "unprognostic (4.92e-2)" "unprognostic (1.80e-1)" "unprognostic (3.16e-2)" "unprognostic (2.56e-2)" "unprognostic (8.72e-3)" "unprognostic (1.90e-3)" "unprognostic (3.69e-1)" "unprognostic (5.00e-2)" "unprognostic (2.21e-1)" "unprognostic (1.37e-1)" "unprognostic (6.14e-2)" "unprognostic (9.62e-2)" "unprognostic (2.78e-1)" "unprognostic (8.79e-3)" TPCN2 TPC2 ENSG00000162341 "Two pore segment channel 2" Q8NHX9 11 69048932-69136316 "Metabolic proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 21.5;Brain excitatory neurons: 20.2;Brain inhibitory neurons: 18.5;Distal convoluted tubule cells: 18.3;Loop of henle epithelial cells: 16.5;Oligodendrocyte progenitor cells: 48.4;Oligodendrocytes: 19.1;Podocytes: 40.8;Proximal tubule cells: 55.2;Renal collecting duct intercalated cells: 16.6;Renal connecting tubule cells: 20.5" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 24.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA016561, HPA027080" Supported Approved Nucleoli NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 77: Intestine - Digestion" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 24: Non-specific - Unknown function" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 3 Nucleoli "HPA016561: , HPA027080: " "unprognostic (7.63e-2)" "unprognostic (7.27e-2)" "unprognostic (1.70e-3)" "unprognostic (7.30e-3)" "unprognostic (5.76e-2)" "unprognostic (1.53e-1)" "unprognostic (6.58e-2)" "unprognostic (6.77e-3)" "unprognostic (1.96e-3)" "unprognostic (2.81e-1)" "validated prognostic favorable (7.62e-6)" "validated prognostic favorable (6.75e-4)" "unprognostic (1.29e-1)" "unprognostic (1.58e-1)" "unprognostic (3.81e-2)" "unprognostic (1.36e-1)" "unprognostic (1.58e-1)" "unprognostic (1.33e-3)" "unprognostic (3.14e-1)" "unprognostic (1.61e-3)" "unprognostic (5.83e-2)" "unprognostic (8.29e-2)" "unprognostic (1.73e-3)" "unprognostic (8.50e-2)" "unprognostic (1.59e-2)" "unprognostic (9.51e-3)" "unprognostic (1.70e-1)" "unprognostic (2.35e-1)" "unprognostic (3.41e-2)" "unprognostic (8.39e-2)" "unprognostic (1.02e-1)" TPD52 "D52, hD52, N8L" ENSG00000076554 "Tumor protein D52" P55327 8 80034745-80231232 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 173.2" "Cell type enhanced" "Detected in many" "B-cells: 327.7;Choroid plexus epithelial cells: 361.4;Plasma cells: 386.3;Salivary ionocytes: 331.5" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 370.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 49.9" "Group enriched" "Detected in many" 5 "B-cells: 49.9;NK-cells: 15.0;T-cells: 21.8" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028427, HPA062167" Enhanced Approved "Golgi apparatus,Primary cilium,Cytosol" NA NA 270000 "Cluster 24: Non-specific - Transcription" "Cluster 42: Retina - Visual perception" "Cluster 14: Neurons - Synaptic function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 18 Cytosol "Golgi apparatus, Primary cilium" "HPA028427: , HPA062167: " "unprognostic (1.12e-1)" "potential prognostic unfavorable (2.39e-5)" "unprognostic (5.20e-2)" "unprognostic (1.27e-1)" "unprognostic (2.61e-2)" "unprognostic (2.86e-1)" "unprognostic (9.73e-2)" "unprognostic (9.86e-2)" "unprognostic (2.54e-1)" "unprognostic (8.53e-2)" "unprognostic (9.93e-2)" "potential prognostic unfavorable (4.72e-4)" "potential prognostic unfavorable (1.50e-6)" "unprognostic (6.21e-3)" "unprognostic (4.98e-3)" "unprognostic (1.42e-2)" "unprognostic (2.89e-1)" "unprognostic (2.53e-1)" "unprognostic (2.82e-1)" "unprognostic (1.28e-1)" "unprognostic (6.15e-2)" "unprognostic (2.08e-1)" "unprognostic (3.21e-2)" "unprognostic (2.19e-1)" "unprognostic (2.50e-1)" "unprognostic (2.30e-2)" "unprognostic (1.57e-1)" "unprognostic (4.56e-2)" "unprognostic (3.89e-1)" "unprognostic (3.26e-1)" "unprognostic (1.68e-2)" TPD52L1 "D53, hD53, TPD53" ENSG00000111907 "TPD52 like 1" Q16890 6 125119049-125264407 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 281.1" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 645.0;Astrocytes: 489.8;Choroid plexus epithelial cells: 741.3;Esophageal apical cells: 1258.2;Esophageal basal cells: 426.6;Esophageal suprabasal cells: 883.0;Lacrimal acinar cells: 491.0;Myonuclei: 857.6;Salivary acinar cells: 694.9" "Cell type enhanced" "Detected in all" "astrocyte: 383.5;choroid plexus epithelial cell: 591.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Prostate - Smooth muscle cells, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027915, HPA027916" Enhanced Approved "Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 76: Non-specific - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 55: Myocytes - Oxidative muscle function" 8 "Plasma membrane, Cell Junctions, Cytosol" "HPA027915: , HPA027916: " "unprognostic (3.54e-1)" "unprognostic (5.78e-2)" "unprognostic (2.50e-2)" "unprognostic (1.65e-2)" "unprognostic (9.35e-2)" "unprognostic (5.25e-2)" "unprognostic (1.93e-1)" "unprognostic (2.44e-1)" "unprognostic (5.21e-2)" "unprognostic (3.79e-3)" "unprognostic (3.83e-2)" "unprognostic (9.60e-3)" "unprognostic (1.65e-1)" "unprognostic (3.78e-3)" "unprognostic (8.04e-2)" "unprognostic (2.70e-1)" "unprognostic (1.86e-1)" "unprognostic (1.39e-1)" "unprognostic (2.37e-1)" "unprognostic (1.07e-1)" "unprognostic (2.68e-1)" "unprognostic (7.44e-3)" "unprognostic (6.22e-3)" "unprognostic (2.92e-1)" "unprognostic (2.96e-2)" "unprognostic (5.04e-2)" "unprognostic (8.72e-2)" "unprognostic (1.86e-1)" "unprognostic (4.71e-2)" "potential prognostic favorable (4.24e-4)" "unprognostic (8.48e-2)" TPD52L2 "D54, hD54, TPD54" ENSG00000101150 "TPD52 like 2" O43399 20 63865228-63891545 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 47.6;Bergmann glia: 36.2;Brain excitatory neurons: 32.2;Brain inhibitory neurons: 30.4;Choroid plexus epithelial cells: 27.1;Distal convoluted tubule cells: 34.7;Ependymal cells: 38.6;Loop of henle epithelial cells: 27.9;Oligodendrocyte progenitor cells: 28.4;Oligodendrocytes: 38.6;Other brain neurons: 34.5;Papillary tip epithelial cells: 27.5;Podocytes: 24.0;Proximal tubule cells: 29.0;Renal collecting duct intercalated cells: 24.0;Renal collecting duct principal cells: 26.2;Renal connecting tubule cells: 28.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047489 Approved Approved Vesicles,Cytosol NA NA 930000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 74: Non-specific - Signal transduction" "Cluster 27: Non-specific - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 102: Non-specific - Mixed function" 21 Vesicles Cytosol "HPA047489: " "unprognostic (1.64e-2)" "potential prognostic unfavorable (4.71e-4)" "unprognostic (2.38e-1)" "unprognostic (6.84e-3)" "unprognostic (8.70e-2)" "unprognostic (8.90e-3)" "unprognostic (3.79e-2)" "unprognostic (2.79e-1)" "unprognostic (1.86e-2)" "unprognostic (9.37e-2)" "potential prognostic unfavorable (6.27e-4)" "unprognostic (3.20e-3)" "unprognostic (1.74e-1)" "validated prognostic unfavorable (4.53e-8)" "validated prognostic unfavorable (6.67e-5)" "unprognostic (1.72e-2)" "unprognostic (1.36e-2)" "unprognostic (3.45e-2)" "unprognostic (6.15e-3)" "unprognostic (1.09e-1)" "unprognostic (1.14e-1)" "unprognostic (6.36e-3)" "potential prognostic unfavorable (4.30e-6)" "unprognostic (5.67e-2)" "unprognostic (6.66e-2)" "unprognostic (2.87e-3)" "unprognostic (1.79e-1)" "unprognostic (3.60e-1)" "unprognostic (2.88e-1)" "potential prognostic unfavorable (1.80e-4)" "unprognostic (1.14e-1)" TPD52L3 "D55, NYD-SP25, TPD55" ENSG00000170777 "TPD52 like 3" Q96J77 9 6328375-6331891 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1295 "testis: 143.6" "Group enriched" "Detected in some" 29 "Early spermatids: 589.5;Late primary spermatocytes: 856.0;Late spermatids: 1988.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 34: Testis cancer - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 4 TPGS1 "C19orf20, GTRGEO22, PGs1" ENSG00000141933 "Tubulin polyglutamylase complex subunit 1" Q6ZTW0 19 507497-519654 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 5.3;granulocytes: 3.9;T-cells: 3.7" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 63.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 12 "unprognostic (1.05e-1)" "unprognostic (1.96e-1)" "unprognostic (2.48e-2)" "unprognostic (1.25e-1)" "unprognostic (8.50e-2)" "unprognostic (2.18e-2)" "unprognostic (2.60e-1)" "unprognostic (4.33e-2)" "unprognostic (1.65e-2)" "unprognostic (1.73e-1)" "unprognostic (1.77e-1)" "unprognostic (1.42e-1)" "unprognostic (2.51e-1)" "unprognostic (1.54e-2)" "unprognostic (1.41e-2)" "unprognostic (1.90e-2)" "unprognostic (3.69e-2)" "unprognostic (1.14e-3)" "unprognostic (1.28e-1)" "unprognostic (5.71e-2)" "unprognostic (6.92e-2)" "unprognostic (9.20e-2)" "unprognostic (1.64e-1)" "unprognostic (1.14e-1)" "unprognostic (4.14e-1)" "unprognostic (1.25e-1)" "unprognostic (2.52e-2)" TPGS2 "C18orf10, DKFZP586M1523, HsT3006, PGs2" ENSG00000134779 "Tubulin polyglutamylase complex subunit 2" Q68CL5 18 36777647-36829216 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 275.5" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 327.5;Early spermatids: 450.0;Late primary spermatocytes: 539.5;Late spermatids: 1756.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 267.4" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040596, HPA040617" Uncertain NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 44: Non-specific - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 1 "HPA040596: , HPA040617: " "unprognostic (2.90e-1)" "unprognostic (1.26e-1)" "unprognostic (2.86e-2)" "unprognostic (2.28e-1)" "unprognostic (2.59e-1)" "unprognostic (1.23e-1)" "unprognostic (2.55e-3)" "unprognostic (5.00e-2)" "unprognostic (3.84e-2)" "unprognostic (1.10e-3)" "unprognostic (4.73e-2)" "unprognostic (3.67e-2)" "potential prognostic unfavorable (1.42e-5)" "unprognostic (1.78e-1)" "unprognostic (4.54e-1)" "unprognostic (2.53e-2)" "unprognostic (1.16e-2)" "unprognostic (6.07e-3)" "unprognostic (1.28e-1)" "potential prognostic unfavorable (7.68e-4)" "unprognostic (1.25e-1)" "unprognostic (4.51e-3)" "unprognostic (7.64e-2)" "unprognostic (2.21e-1)" "unprognostic (1.70e-1)" "unprognostic (3.72e-2)" "unprognostic (7.05e-2)" "unprognostic (3.92e-1)" "unprognostic (3.90e-1)" TPH1 "TPH, TPRH" ENSG00000129167 "Tryptophan hydroxylase 1" P17752 11 18017555-18046269 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Serotonin biosynthesis" "Monooxygenase, Oxidoreductase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "choroid plexus: 6.4;intestine: 18.6;stomach 1: 14.5" "Cell type enriched" "Detected in some" 13 "Neuroendocrine cells: 570.3" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 13.8" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 5.1" "Region enhanced" "Detected in all" "midbrain: 22.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "pancreatic cancer: 15.3" "Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB010767, HPA022483" Uncertain Approved Cytosol NA NA "Cluster 77: Intestine - Digestion" "Cluster 44: Non-specific - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" 4 Cytosol "CAB010767: , HPA022483: " "unprognostic (5.29e-2)" "unprognostic (2.64e-1)" "unprognostic (1.05e-1)" "unprognostic (8.69e-2)" "unprognostic (3.64e-1)" "unprognostic (1.55e-2)" "unprognostic (3.65e-1)" "unprognostic (5.33e-3)" "unprognostic (1.21e-2)" "unprognostic (2.14e-2)" "unprognostic (8.71e-2)" "unprognostic (2.24e-2)" "unprognostic (1.58e-1)" "unprognostic (8.52e-3)" TPH2 "FLJ37295, NTPH" ENSG00000139287 "Tryptophan hydroxylase 2" Q8IWU9 12 71938845-72186618 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Serotonin biosynthesis" "Monooxygenase, Oxidoreductase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 5 "Epicardial cells: 141.0" "Cell type enhanced" "Detected in many" "splatter: 28.5" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "midbrain: 631.8;pons: 271.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "head and neck cancer: 2.3" "Testis - Early spermatids, Testis - Late spermatids" "Group enriched" "Detected in many" 31 "midbrain: 106.7;pons and medulla: 34.9" "Group enriched" "Detected in some" 5 "midbrain: 63.3;pons: 62.2" CAB078198 Enhanced NA NA "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 65: Non-specific - Unknown function" "Cluster 109: Neurons - Neuronal signaling" "CAB078198: " "unprognostic (1.13e-2)" TPI1 ENSG00000111669 "Triosephosphate isomerase 1" P60174 12 6867119-6870948 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Gluconeogenesis, Glycolysis" "Isomerase, Lyase" "Cancer-related genes, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 2315.7;tongue: 1873.5" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 5404.6;Esophageal basal cells: 1694.7;Esophageal suprabasal cells: 2600.0;Extravillous trophoblasts: 2184.7;Migrating cytotrophoblasts: 1772.3;Syncytiotrophoblasts: 1737.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050924, HPA053568" Uncertain Approved Nucleoplasm NA NA 83000000 "Cluster 29: Non-specific - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 14: Neurons - Synaptic function" "Cluster 38: Non-specific - Transcription" "Cluster 85: Squamous epithelial cells - Keratinization" 32 Nucleoplasm "HPA050924: , HPA053568: " "potential prognostic unfavorable (2.28e-4)" "unprognostic (1.30e-1)" "unprognostic (3.76e-1)" "unprognostic (1.07e-1)" "unprognostic (3.43e-1)" "unprognostic (5.78e-2)" "unprognostic (2.57e-2)" "unprognostic (3.11e-1)" "unprognostic (6.91e-3)" "unprognostic (4.46e-3)" "unprognostic (9.07e-3)" "unprognostic (1.12e-1)" "unprognostic (3.10e-2)" "validated prognostic unfavorable (3.11e-5)" "validated prognostic unfavorable (7.83e-11)" "potential prognostic unfavorable (5.69e-5)" "unprognostic (1.75e-3)" "unprognostic (4.01e-2)" "unprognostic (3.71e-1)" "unprognostic (4.71e-2)" "unprognostic (1.01e-1)" "unprognostic (2.62e-2)" "unprognostic (5.87e-2)" "unprognostic (1.24e-1)" "unprognostic (2.29e-1)" "unprognostic (4.12e-2)" "unprognostic (1.62e-1)" "unprognostic (7.84e-2)" "unprognostic (3.38e-1)" "unprognostic (5.13e-2)" "unprognostic (1.19e-1)" TPK1 "HTPK1, PP20" ENSG00000196511 "Thiamin pyrophosphokinase 1" Q9H3S4 7 144451941-144836395 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 13.1" "Cell type enhanced" "Detected in many" "Microglia: 250.4;Neutrophils: 739.0" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 4 "Kidney Renal Papillary Cell Carcinoma (TCGA): 36.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Kidney cancer: 15.0" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021545, HPA021849" Approved Approved Vesicles NA NA 74000 "Cluster 33: Non-specific - ATP binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 24: Neutrophils - Innate immunity signal integration" 10 Vesicles "HPA021545: , HPA021849: " "potential prognostic favorable (8.65e-5)" "unprognostic (2.78e-1)" "unprognostic (1.72e-1)" "unprognostic (2.54e-2)" "unprognostic (4.49e-2)" "unprognostic (4.90e-2)" "unprognostic (3.44e-2)" "unprognostic (1.07e-1)" "unprognostic (1.91e-1)" "unprognostic (2.78e-2)" "potential prognostic favorable (2.79e-5)" "unprognostic (1.59e-1)" "unprognostic (1.05e-3)" "unprognostic (2.06e-2)" "unprognostic (3.09e-1)" "unprognostic (2.29e-1)" "unprognostic (1.03e-1)" "unprognostic (2.07e-2)" "unprognostic (2.29e-2)" "unprognostic (3.11e-1)" "unprognostic (2.73e-1)" "unprognostic (1.90e-1)" "unprognostic (2.79e-1)" "unprognostic (9.98e-2)" "unprognostic (4.25e-2)" "unprognostic (1.87e-1)" "unprognostic (2.44e-1)" "unprognostic (1.74e-1)" "unprognostic (2.97e-1)" "unprognostic (1.24e-1)" "unprognostic (8.41e-2)" TPM1 "C15orf13, CMH3" ENSG00000140416 "Tropomyosin 1" P09493 15 63042632-63071915 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Actin-binding, Muscle protein" "Cancer-related genes, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 10511.2;skeletal muscle: 11880.5" "Cell type enhanced" "Detected in all" "Breast myoepithelial cells: 3061.2;Decidual stromal cells: 1545.5;Extravillous trophoblasts: 4740.9;Hepatic stellate cells: 2633.6;Megakaryocytes: 1947.2;Pancreatic acinar cells: 1818.5;Smooth muscle cells: 5778.4;Thymic myoid cells: 2042.2;Tuft cells: 1533.2;Vascular smooth muscle cells: 2223.4" "Cell type enhanced" "Detected in all" "fibroblast: 737.0;vascular associated smooth muscle cell: 1012.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 48.9" "Group enriched" "Detected in all" 4 "dendritic cells: 14.1;granulocytes: 48.9;monocytes: 19.2" "Cancer enhanced" "Detected in all" "testis cancer: 3510.1" "Adipose subcutaneous - Smooth muscle cells, Colon - Smooth muscle cells, Heart muscle - Cardiomyocytes, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000261, HPA009066, CAB017698, HPA047089, HPA053624" Supported Approved "Actin filaments,Cytosol" NA NA 130000000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 62: Smooth muscle cells - Muscle contraction" 35 "Actin filaments" Cytosol "CAB017698: , HPA000261: , HPA009066: , HPA047089: , HPA053624: " "unprognostic (2.11e-1)" "unprognostic (1.40e-1)" "unprognostic (1.30e-1)" "unprognostic (2.15e-2)" "unprognostic (2.64e-2)" "unprognostic (1.91e-1)" "unprognostic (3.28e-1)" "unprognostic (7.59e-2)" "unprognostic (7.77e-3)" "potential prognostic unfavorable (3.40e-5)" "potential prognostic favorable (2.12e-7)" "unprognostic (1.49e-2)" "unprognostic (1.13e-1)" "unprognostic (6.46e-2)" "unprognostic (1.27e-1)" "unprognostic (9.47e-3)" "unprognostic (1.24e-1)" "unprognostic (1.57e-1)" "unprognostic (9.70e-3)" "unprognostic (3.53e-2)" "unprognostic (2.13e-2)" "unprognostic (2.83e-2)" "unprognostic (1.65e-1)" "unprognostic (6.39e-2)" "unprognostic (8.51e-3)" "unprognostic (7.75e-2)" "unprognostic (5.11e-2)" "unprognostic (1.11e-1)" "unprognostic (2.33e-1)" "unprognostic (1.66e-2)" "unprognostic (2.35e-2)" TPM2 "AMCD1, DA1, NEM4" ENSG00000198467 "Tropomyosin 2" P07951 9 35681992-35690056 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Muscle protein" "Cancer-related genes, Disease variant, Nemaline myopathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 36557.0;tongue: 15656.5" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 4190.9;Decidual stromal cells: 2342.1;Hepatic stellate cells: 2601.3;Pericytes: 1130.5;Peritubular myoid cells: 1764.0;Salivary myoepithelial cells: 2135.0;Smooth muscle cells: 8892.0;Vascular smooth muscle cells: 5605.5" "Cell type enriched" "Detected in many" 6 "vascular associated smooth muscle cell: 1056.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 811 "plasmacytoid DC: 399.5" "Lineage enriched" "Detected in single" 922 "dendritic cells: 399.5" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Colon - Smooth muscle cells, Heart muscle - Cardiomyocytes, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Skin - Smooth muscle cells, Spleen - Fibroblasts_1, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047089, HPA053624" Approved NA NA 160000000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 23: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 12 "HPA047089: , HPA053624: " "unprognostic (8.52e-3)" "unprognostic (7.54e-2)" "unprognostic (4.08e-1)" "unprognostic (2.50e-2)" "potential prognostic unfavorable (3.92e-4)" "unprognostic (7.27e-2)" "unprognostic (1.56e-1)" "unprognostic (2.22e-1)" "unprognostic (4.51e-3)" "unprognostic (1.91e-1)" "unprognostic (2.70e-2)" "unprognostic (3.53e-2)" "potential prognostic unfavorable (2.83e-4)" "unprognostic (9.82e-3)" "unprognostic (9.47e-2)" "unprognostic (4.72e-3)" "unprognostic (1.53e-3)" "unprognostic (2.89e-2)" "unprognostic (8.42e-2)" "unprognostic (3.14e-2)" "unprognostic (1.04e-1)" "unprognostic (5.48e-2)" "unprognostic (5.42e-2)" "unprognostic (4.45e-2)" "unprognostic (2.15e-2)" "unprognostic (1.41e-1)" "unprognostic (1.05e-1)" "unprognostic (7.59e-3)" "unprognostic (1.21e-1)" "unprognostic (4.84e-3)" "unprognostic (1.44e-1)" TPM3 "NEM1, TRK" ENSG00000143549 "Tropomyosin 3" P06753 1 154155308-154194648 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Muscle protein" "Cancer-related genes, Disease variant, Nemaline myopathy, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 12 "skeletal muscle: 8344.9;tongue: 5701.1" "Cell type enhanced" "Detected in all" "Megakaryocytes: 1446.5;Myonuclei: 2480.5;Neutrophil progenitors: 866.2;Neutrophils: 1395.2;Platelets: 1752.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000261, HPA009066, HPA047089, HPA053624" Approved Approved "Actin filaments,Cytosol" NA NA 170000000 "Cluster 29: Non-specific - Unknown function" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 14: Neurons - Synaptic function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 55: Myocytes - Oxidative muscle function" 57 "Actin filaments" Cytosol "HPA000261: , HPA009066: , HPA047089: , HPA053624: " "potential prognostic unfavorable (4.47e-4)" "unprognostic (4.44e-1)" "unprognostic (2.09e-1)" "unprognostic (2.21e-2)" "unprognostic (8.97e-3)" "unprognostic (6.15e-2)" "unprognostic (1.25e-1)" "unprognostic (1.44e-1)" "unprognostic (1.79e-3)" "unprognostic (1.76e-2)" "potential prognostic favorable (1.08e-4)" "unprognostic (1.55e-1)" "unprognostic (2.37e-3)" "potential prognostic unfavorable (9.87e-6)" "unprognostic (2.29e-3)" "unprognostic (2.17e-3)" "unprognostic (1.24e-2)" "unprognostic (3.64e-3)" "unprognostic (1.93e-2)" "unprognostic (5.08e-3)" "unprognostic (2.29e-1)" "unprognostic (3.54e-3)" "unprognostic (2.07e-1)" "unprognostic (2.45e-1)" "unprognostic (7.02e-2)" "unprognostic (4.94e-2)" "unprognostic (4.21e-2)" "unprognostic (1.31e-1)" "unprognostic (2.32e-1)" "unprognostic (1.19e-1)" "unprognostic (3.78e-1)" TPM4 ENSG00000167460 "Tropomyosin 4" P67936 19 16067021-16103002 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Muscle protein" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 2395.1;Megakaryocytes: 4036.6;Neutrophils: 1466.5;Platelets: 3392.8" "Cell type enhanced" "Detected in all" "vascular associated smooth muscle cell: 345.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "CAB004685, HPA047089, HPA053624" Approved Approved "Actin filaments,Cytosol" NA NA 410000000 "Cluster 33: Non-specific - ATP binding" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 25: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 47: Platelets - Hemostasis" 25 "Actin filaments" Cytosol "CAB004685: , HPA047089: , HPA053624: " "unprognostic (1.88e-1)" "unprognostic (1.55e-2)" "unprognostic (1.98e-1)" "unprognostic (2.01e-2)" "unprognostic (2.21e-1)" "unprognostic (3.25e-2)" "unprognostic (1.89e-1)" "unprognostic (5.36e-2)" "unprognostic (2.46e-1)" "unprognostic (4.43e-1)" "unprognostic (3.68e-2)" "unprognostic (1.71e-1)" "potential prognostic unfavorable (1.60e-4)" "unprognostic (2.97e-2)" "unprognostic (1.38e-1)" "unprognostic (5.27e-3)" "potential prognostic unfavorable (6.65e-4)" "unprognostic (3.76e-2)" "unprognostic (6.74e-2)" "potential prognostic unfavorable (3.60e-4)" "unprognostic (7.89e-3)" "unprognostic (3.29e-3)" "unprognostic (1.18e-1)" "unprognostic (2.86e-1)" "unprognostic (6.55e-2)" "unprognostic (2.00e-1)" "unprognostic (4.14e-2)" "unprognostic (5.28e-2)" "unprognostic (1.65e-1)" "unprognostic (4.15e-3)" "unprognostic (3.47e-1)" TPMT ENSG00000137364 "Thiopurine S-methyltransferase" P51580 6 18128311-18155077 "Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 71.3;liver: 64.3;thyroid gland: 72.0" "Cell type enhanced" "Detected in all" "Colonocytes: 201.5;Enterocytes: 164.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Prostate - Prostate glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019851, HPA062364" Enhanced NA NA 29000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 76: Non-specific - Metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 1 "HPA019851: , HPA062364: " "unprognostic (1.33e-3)" "unprognostic (1.20e-1)" "unprognostic (1.58e-1)" "unprognostic (1.98e-1)" "unprognostic (7.09e-2)" "unprognostic (6.41e-3)" "unprognostic (1.75e-2)" "unprognostic (5.06e-2)" "unprognostic (4.16e-1)" "unprognostic (1.38e-3)" "potential prognostic favorable (5.41e-9)" "unprognostic (5.11e-3)" "potential prognostic favorable (5.64e-5)" "unprognostic (7.02e-2)" "potential prognostic favorable (7.83e-5)" "unprognostic (3.22e-1)" "unprognostic (1.25e-1)" "unprognostic (1.05e-2)" "unprognostic (1.53e-1)" "potential prognostic favorable (1.17e-4)" "unprognostic (3.85e-2)" "unprognostic (2.22e-1)" "unprognostic (1.36e-1)" "unprognostic (1.27e-1)" "unprognostic (2.93e-2)" "unprognostic (4.83e-2)" "unprognostic (3.99e-2)" "unprognostic (5.77e-2)" "unprognostic (2.38e-1)" "unprognostic (1.41e-1)" "unprognostic (8.91e-2)" TPO TPX ENSG00000115705 "Thyroid peroxidase" P07202 2 1374066-1543711 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrogen peroxide, Thyroid hormones biosynthesis" "Oxidoreductase, Peroxidase" "Congenital hypothyroidism, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 73 "thyroid gland: 1387.6" "Cell type enriched" "Detected in some" 4 "Oocytes: 87.5" "Cell type enhanced" "Detected in many" "endothelial cell: 6.8;lower rhombic lip: 6.6" "Cancer enriched" "Detected in some" 503 "Thyroid Carcinoma (TCGA): 512.0" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 12 "memory CD4 T-cell: 2.0;T-reg: 1.2" "Lineage enriched" "Detected in single" 20 "T-cells: 2.0" "Group enriched" "Detected in some" 6 "Myeloma: 4.7;thyroid cancer: 6.1" "Pituitary gland - Corticotropes, Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA007987, CAB009587, HPA073226" Enhanced "Intracellular and membrane" Enzyme NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 33: Thyroid gland - Tissue development" "Cluster 53: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "CAB009587: , HPA007987: , HPA073226: " "unprognostic (4.43e-2)" "unprognostic (1.03e-1)" "unprognostic (1.33e-2)" TPP1 "CLN2, LPIC, SCAR7, TPP-1" ENSG00000166340 "Tripeptidyl peptidase 1" O14773 11 6612768-6619448 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Disease variant, Epilepsy, Neurodegeneration, Neuronal ceroid lipofuscinosis, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 96.0;Astrocytes: 40.3;Choroid plexus epithelial cells: 37.0;Microglia: 32.4;Platelets: 35.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adrenal gland - Adrenal cortex cells, Lung - Macrophages, Minor Salivary Gland - Macrophages, Prostate - Macrophages, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037709, HPA044868" Enhanced "Intracellular and membrane" Enzyme NA NA 4500000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 21: Non-specific - Metabolism" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 18: Adrenal cortex cells - Steroidogensis" 20 "HPA037709: , HPA044868: " "unprognostic (8.24e-2)" "unprognostic (8.48e-2)" "unprognostic (3.59e-2)" "unprognostic (2.52e-3)" "unprognostic (4.06e-2)" "unprognostic (5.44e-3)" "unprognostic (4.72e-2)" "potential prognostic unfavorable (6.30e-4)" "potential prognostic unfavorable (4.68e-4)" "unprognostic (4.97e-2)" "potential prognostic favorable (3.02e-4)" "unprognostic (2.61e-2)" "unprognostic (4.21e-2)" "unprognostic (1.73e-2)" "unprognostic (1.08e-1)" "unprognostic (2.01e-1)" "unprognostic (2.07e-2)" "unprognostic (3.39e-2)" "unprognostic (2.02e-2)" "unprognostic (8.80e-2)" "unprognostic (4.27e-2)" "unprognostic (8.31e-2)" "unprognostic (2.41e-1)" "unprognostic (4.83e-2)" "unprognostic (1.68e-1)" "unprognostic (8.53e-2)" "unprognostic (9.81e-2)" "potential prognostic unfavorable (6.52e-4)" "unprognostic (5.10e-2)" "unprognostic (4.01e-2)" "unprognostic (1.35e-1)" TPP2 TPPII ENSG00000134900 "Tripeptidyl peptidase 2" P29144 13 102596958-102679958 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Protease, Serine protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 825.6;Late primary spermatocytes: 624.4;Late spermatids: 1459.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021069, HPA049630" Approved Supported "Nuclear bodies,Cytosol" NA NA 630000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 19: Non-specific - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 22 "Nuclear bodies, Cytosol" "HPA021069: , HPA049630: " "unprognostic (3.45e-1)" "unprognostic (1.16e-1)" "unprognostic (1.64e-1)" "potential prognostic unfavorable (1.29e-4)" "unprognostic (2.36e-1)" "unprognostic (2.29e-1)" "unprognostic (2.63e-2)" "potential prognostic favorable (3.98e-4)" "unprognostic (3.38e-1)" "potential prognostic unfavorable (8.24e-7)" "unprognostic (1.34e-3)" "unprognostic (8.54e-3)" "unprognostic (1.74e-1)" "unprognostic (8.58e-2)" "unprognostic (3.26e-2)" "unprognostic (2.71e-1)" "unprognostic (2.40e-3)" "unprognostic (1.51e-2)" "unprognostic (1.25e-1)" "unprognostic (3.81e-3)" "unprognostic (2.69e-1)" "unprognostic (5.82e-2)" "unprognostic (1.11e-1)" "unprognostic (1.86e-1)" "unprognostic (3.14e-2)" "unprognostic (7.94e-3)" "unprognostic (1.21e-2)" "unprognostic (1.08e-1)" "unprognostic (3.11e-1)" "unprognostic (5.77e-2)" "unprognostic (2.10e-1)" TPPP "p25, p25alpha, TPPP/p25, TPPP1" ENSG00000171368 "Tubulin polymerization promoting protein" O94811 5 659862-693352 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 133.3" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 41.8;Brain inhibitory neurons: 45.3;Corticotrophs: 38.9;Endometrial ciliated cells: 35.5;Ependymal cells: 41.6;Fallopian tube ciliated cells: 45.0;Oligodendrocytes: 125.0;Other brain neurons: 41.9;Respiratory ciliated cells: 38.4;Thyrotrophs: 37.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal medulla cells, Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036575, HPA036576" Enhanced Supported Mitochondria,Cytosol NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 34: Non-specific - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 80: Oligodendrocytes - Myelination" 16 "Mitochondria, Cytosol" "HPA036575: , HPA036576: " "unprognostic (2.87e-2)" "unprognostic (1.36e-1)" "unprognostic (6.03e-2)" "unprognostic (2.02e-1)" "unprognostic (4.69e-2)" "unprognostic (3.89e-2)" "unprognostic (4.35e-2)" "unprognostic (1.90e-1)" "unprognostic (1.84e-2)" "unprognostic (1.81e-2)" "potential prognostic favorable (2.17e-5)" "unprognostic (4.45e-3)" "unprognostic (1.14e-2)" "unprognostic (1.53e-1)" "unprognostic (5.42e-2)" "unprognostic (6.59e-3)" "unprognostic (2.40e-2)" "unprognostic (2.30e-1)" "unprognostic (4.28e-2)" "unprognostic (1.86e-1)" "unprognostic (8.34e-2)" "unprognostic (2.91e-3)" "unprognostic (1.00e-1)" "unprognostic (7.92e-3)" "unprognostic (1.01e-1)" "unprognostic (2.18e-1)" "unprognostic (3.99e-1)" "unprognostic (4.01e-2)" "unprognostic (1.34e-1)" "unprognostic (2.36e-2)" "unprognostic (9.53e-2)" TPPP2 "C14orf8, CT152, p18, p25beta" ENSG00000179636 "Tubulin polymerization promoting protein family member 2" P59282 14 21024109-21036276 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "testis: 251.0" "Cell type enriched" "Detected in some" 7 "Late spermatids: 16490.7" "Cell type enhanced" "Detected in some" "astrocyte: 1.2;Bergmann glia: 1.3;ependymal cell: 1.1" "Cancer enhanced" "Detected in single" "Liver Hepatocellular Carcinoma (TCGA): 1.6" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA004120 Enhanced Approved "Connecting piece,Mid piece,Principal piece" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 3: Choroid plexus - Cilium" "Cluster 18: Liver cancer - Metabolism" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" "Connecting piece, Mid piece, Principal piece" "HPA004120: " "potential prognostic favorable (1.53e-4)" "unprognostic (8.67e-3)" TPPP3 "CGI-38, p20, p25gamma" ENSG00000159713 "Tubulin polymerization promoting protein family member 3" Q9BW30 16 67389809-67393518 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 320.0;fallopian tube: 807.5" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 1037.8;Epididymal efferent duct ciliated cells: 2221.5;Fallopian tube ciliated cells: 1942.4;Melanocytes: 505.7;Respiratory ciliated cells: 1873.0;Suprabasal keratinocytes: 298.0" "Cell type enriched" "Detected in many" 6 "ependymal cell: 315.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 66.0" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Gastric cancer: 58.6" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Kidney - Podocytes, Lung - Respiratory ciliated cells, Minor Salivary Gland - Fibroblasts, Pituitary gland - Thyrotropes, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061691 Enhanced NA NA 48000 "Cluster 40: Monocytes - Innate immune response" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" 1 "HPA061691: " "potential prognostic unfavorable (6.70e-4)" "unprognostic (2.19e-1)" "unprognostic (8.09e-2)" "unprognostic (1.29e-2)" "unprognostic (1.28e-1)" "unprognostic (1.09e-2)" "unprognostic (1.49e-3)" "potential prognostic unfavorable (5.56e-5)" "unprognostic (3.00e-3)" "unprognostic (5.90e-2)" "unprognostic (2.12e-2)" "potential prognostic favorable (6.19e-4)" "unprognostic (2.87e-2)" "unprognostic (6.85e-2)" "unprognostic (2.37e-1)" "unprognostic (1.06e-1)" "unprognostic (4.38e-3)" "unprognostic (7.02e-3)" "unprognostic (3.01e-1)" "unprognostic (7.80e-3)" "unprognostic (5.67e-2)" "unprognostic (3.33e-3)" "unprognostic (5.41e-3)" "unprognostic (6.91e-2)" "unprognostic (1.54e-1)" "unprognostic (3.39e-1)" "unprognostic (9.56e-2)" "unprognostic (7.31e-2)" "unprognostic (2.04e-1)" "unprognostic (8.93e-2)" "unprognostic (2.04e-1)" TPR ENSG00000047410 "Translocated promoter region, nuclear basket protein" P12270 1 186311652-186375693 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis, mRNA transport, Protein transport, Translocation, Transport" "Cancer-related genes, Disease variant, Intellectual disability, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early primary spermatocytes: 662.1;Epicardial cells: 1373.6;Late primary spermatocytes: 644.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019661, HPA019663, HPA024336" Enhanced Enhanced "Nuclear membrane" NA NA 100000000 "Cluster 35: Neutrophils - Protein binding" "Cluster 39: Testis - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 38 "Nuclear membrane" "HPA019661: , HPA019663: , HPA024336: " "unprognostic (2.68e-1)" "unprognostic (2.75e-1)" "unprognostic (2.75e-1)" "potential prognostic unfavorable (1.35e-4)" "unprognostic (3.29e-1)" "unprognostic (8.34e-2)" "unprognostic (5.02e-3)" "unprognostic (5.58e-2)" "unprognostic (6.90e-2)" "unprognostic (1.42e-2)" "potential prognostic favorable (5.85e-4)" "unprognostic (1.26e-2)" "unprognostic (1.59e-2)" "unprognostic (4.77e-3)" "unprognostic (3.66e-2)" "unprognostic (8.77e-2)" "unprognostic (4.50e-3)" "unprognostic (1.76e-1)" "unprognostic (2.49e-2)" "unprognostic (2.91e-1)" "unprognostic (2.76e-1)" "unprognostic (1.25e-2)" "unprognostic (2.61e-2)" "unprognostic (4.49e-2)" "unprognostic (1.19e-1)" "unprognostic (3.03e-1)" "unprognostic (3.04e-2)" "unprognostic (3.62e-1)" "unprognostic (1.78e-1)" "unprognostic (4.03e-3)" "unprognostic (3.52e-1)" TPRA1 "FLJ32197, GPR175, TMEM227, TPRA40" ENSG00000163870 "Transmembrane protein adipocyte associated 1" Q86W33 3 127571232-127598267 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "cDC: 123.9;Endometrial secretory cells: 163.0;Esophageal apical cells: 120.7;Neutrophils: 148.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019784 Approved Approved Vesicles NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" Vesicles "HPA019784: " "unprognostic (2.91e-1)" "unprognostic (2.64e-2)" "unprognostic (1.09e-1)" "unprognostic (1.08e-2)" "unprognostic (2.89e-2)" "unprognostic (4.01e-3)" "unprognostic (5.85e-2)" "unprognostic (2.80e-2)" "unprognostic (2.54e-1)" "unprognostic (6.87e-2)" "unprognostic (1.61e-1)" "unprognostic (7.59e-2)" "unprognostic (8.08e-2)" "potential prognostic unfavorable (5.11e-4)" "unprognostic (2.54e-2)" "unprognostic (4.26e-2)" "unprognostic (6.75e-2)" "unprognostic (3.09e-1)" "unprognostic (1.39e-1)" "unprognostic (1.53e-1)" "unprognostic (5.96e-2)" "unprognostic (6.98e-2)" "unprognostic (2.15e-1)" "unprognostic (1.28e-1)" "unprognostic (2.81e-1)" "unprognostic (2.39e-1)" "unprognostic (3.09e-2)" "unprognostic (2.65e-1)" "unprognostic (1.47e-1)" "unprognostic (2.12e-1)" "unprognostic (1.89e-1)" TPRG1 "FAM79B, FLJ41238, FLJ43694" ENSG00000188001 "Tumor protein p63 regulated 1" Q6ZUI0 3 188947214-189325304 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 28.2;esophagus: 49.1;vagina: 31.9" "Group enriched" "Detected in many" 4 "Adipocytes: 751.8;Esophageal apical cells: 2784.8" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 144.8;leukocyte: 108.8" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 45.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Esophageal cancer: 7.8;lymphoma: 10.1" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA044751, HPA060187" Uncertain Supported Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 84: Apical squamous epithelium - Cornification" 16 Nucleoplasm "HPA044751: , HPA060187: " "unprognostic (3.04e-1)" "unprognostic (2.97e-3)" "unprognostic (1.98e-1)" "unprognostic (1.71e-3)" "unprognostic (2.62e-2)" "unprognostic (1.32e-2)" "unprognostic (1.12e-2)" "unprognostic (1.10e-1)" "potential prognostic unfavorable (2.12e-5)" "unprognostic (3.04e-3)" "unprognostic (2.15e-2)" "unprognostic (5.57e-3)" "unprognostic (1.67e-1)" "unprognostic (1.30e-2)" "unprognostic (3.91e-2)" "unprognostic (2.82e-2)" "unprognostic (5.16e-1)" "unprognostic (1.27e-2)" "unprognostic (8.31e-3)" "unprognostic (1.90e-1)" "unprognostic (3.70e-2)" "unprognostic (6.87e-2)" "unprognostic (2.55e-2)" "unprognostic (2.42e-1)" "unprognostic (9.53e-2)" TPRG1L "FAM79A, FLJ21811, h-Mover, RP11-46F15.3, SVAP30, TPRGL" ENSG00000158109 "Tumor protein p63 regulated 1 like" Q5T0D9 1 3625015-3630127 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 81.3;Platelets: 79.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063163, CAB079051" Supported Approved "Vesicles,Plasma membrane" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 24: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" Vesicles "Plasma membrane" "CAB079051: , HPA063163: " "unprognostic (2.25e-1)" "unprognostic (1.62e-2)" "unprognostic (3.28e-1)" "unprognostic (2.07e-1)" "unprognostic (2.50e-1)" "unprognostic (8.36e-2)" "unprognostic (6.36e-2)" "unprognostic (1.01e-1)" "unprognostic (1.22e-1)" "unprognostic (3.07e-1)" "validated prognostic favorable (4.73e-13)" "validated prognostic favorable (1.51e-5)" "unprognostic (4.55e-2)" "unprognostic (1.84e-1)" "unprognostic (1.41e-2)" "unprognostic (8.38e-2)" "unprognostic (2.28e-1)" "unprognostic (8.74e-2)" "unprognostic (1.31e-1)" "unprognostic (3.01e-2)" "unprognostic (8.02e-2)" "unprognostic (3.86e-2)" "unprognostic (6.77e-2)" "unprognostic (5.72e-2)" "unprognostic (1.99e-1)" "unprognostic (1.23e-1)" "unprognostic (1.31e-1)" "unprognostic (2.11e-1)" "unprognostic (3.63e-2)" "unprognostic (1.06e-1)" "unprognostic (1.23e-1)" TPRKB "CGI-121, CGI121" ENSG00000144034 "TP53RK binding protein" Q9Y3C4 2 73729104-73737400 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "tRNA processing" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal efferent duct absorptive cells: 205.4;Late primary spermatocytes: 377.0;Megakaryocytes: 216.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035712 Approved Supported Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 2: Neurons - Nucleosome" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 14 Cytosol "HPA035712: " "unprognostic (4.43e-3)" "unprognostic (9.16e-2)" "unprognostic (1.26e-1)" "unprognostic (6.13e-2)" "unprognostic (4.04e-1)" "unprognostic (1.39e-3)" "unprognostic (2.33e-1)" "unprognostic (2.51e-2)" "unprognostic (3.78e-3)" "unprognostic (3.09e-2)" "unprognostic (3.37e-3)" "unprognostic (1.07e-1)" "unprognostic (3.24e-1)" "validated prognostic unfavorable (3.38e-5)" "validated prognostic unfavorable (2.18e-6)" "potential prognostic unfavorable (3.07e-5)" "unprognostic (3.33e-2)" "unprognostic (3.68e-2)" "unprognostic (6.17e-2)" "unprognostic (4.07e-2)" "unprognostic (8.24e-3)" "validated prognostic unfavorable (1.60e-5)" "validated prognostic unfavorable (7.16e-4)" "unprognostic (2.43e-1)" "unprognostic (5.01e-2)" "unprognostic (1.11e-1)" "potential prognostic unfavorable (9.98e-6)" "unprognostic (2.21e-1)" "unprognostic (4.67e-2)" "unprognostic (8.67e-2)" "unprognostic (3.04e-1)" TPRN "C9orf75, DFNB79, FLJ90254" ENSG00000176058 Taperin Q4KMQ1 9 137191617-137204193 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hearing "Actin-binding, Protein phosphatase inhibitor" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 55.9;pancreas: 89.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 57.3;Colonocytes: 138.0;Enterocytes: 90.6;Esophageal apical cells: 58.4;Goblet cells: 59.4;Oligodendrocytes: 58.8;Pancreatic acinar cells: 89.5;Retinal pigment epithelial cells: 106.6" "Cell type enhanced" "Detected in all" "oligodendrocyte: 61.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 48.0" "HPA020899, HPA076667" Approved Approved "Plasma membrane" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 70: Non-specific - Protein processing" "Cluster 11: White matter - Signal transduction" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 18 "Plasma membrane" "HPA020899: , HPA076667: " "unprognostic (8.09e-2)" "unprognostic (7.69e-2)" "unprognostic (9.23e-3)" "unprognostic (1.40e-2)" "unprognostic (2.09e-1)" "unprognostic (5.59e-2)" "unprognostic (5.63e-2)" "unprognostic (4.53e-2)" "unprognostic (5.14e-2)" "unprognostic (1.88e-2)" "potential prognostic favorable (2.17e-7)" "unprognostic (2.30e-3)" "unprognostic (4.75e-3)" "potential prognostic unfavorable (7.49e-4)" "unprognostic (5.32e-3)" "unprognostic (8.82e-2)" "unprognostic (1.61e-1)" "unprognostic (2.21e-1)" "unprognostic (5.68e-2)" "unprognostic (3.24e-1)" "unprognostic (5.56e-1)" "unprognostic (2.38e-1)" "unprognostic (3.48e-3)" "unprognostic (9.31e-2)" "unprognostic (1.93e-2)" "unprognostic (1.52e-3)" "unprognostic (1.18e-1)" "unprognostic (1.15e-2)" "unprognostic (5.42e-2)" "unprognostic (1.84e-1)" "unprognostic (2.87e-2)" TPRX1 FLJ40321 ENSG00000178928 "Tetrapeptide repeat homeobox 1" 19 47801232-47819051 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 11 "retina: 1.0;testis: 1.1" "Cell type enhanced" "Detected in some" "Early primary spermatocytes: 2.4;Epididymal principal cells: 2.7;Retinal bipolar cells: 2.3;Retinal ganglion cells: 3.9;Rod photoreceptor cells: 12.0;Sertoli cells: 2.2;Thymic myoid cells: 2.7" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 12 "Testicular Germ Cell Tumor (TCGA): 2.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 8 "Uterine cancer: 1.1" HPA044922 Uncertain NA NA "Cluster 47: Testis - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 1: Neuronal - Visual perception" "Cluster 79: Photoreceptor cells - Phototransduction" "HPA044922: " "unprognostic (2.71e-1)" TPRX2 "TPRX2P, TPRX2P1" ENSG00000259009 "Tetrapeptide repeat homeobox 2" P0DV77 19 47859235-47861721 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 1: Neuronal - Visual perception" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" TPSAB1 "TPS1, TPS2, TPSB1" ENSG00000172236 "Tryptase alpha/beta 1" Q15661 16 1240379-1242554 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 325 "Mast cells: 8486.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 900 "basophil: 90.0" "Lineage enriched" "Detected in single" 900 "granulocytes: 90.0" "Cancer enriched" "Detected in some" 29 "Leukemia: 82.8" "Adipose subcutaneous - Mast cells, Adipose visceral - Mast cells, Breast - Fibroblasts, Colon - Mast cells, Lung - Mast cells, Minor Salivary Gland - Mast cells, Skeletal muscle - Macrophages" "CAB016369, CAB022175, HPA049153, HPA049554" Supported Approved Vesicles "Secreted to blood" Enzyme NA NA 59000000 "Cluster 46: Basophils - Proteolysis" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 58: Mast cells - Allergic inflammatory responses" Vesicles "CAB016369: , CAB022175: , HPA049153: , HPA049554: " "unprognostic (1.38e-2)" "unprognostic (2.27e-2)" "unprognostic (9.04e-2)" "unprognostic (1.42e-2)" "unprognostic (3.12e-1)" "unprognostic (5.01e-2)" "unprognostic (3.14e-2)" "potential prognostic favorable (4.17e-5)" "unprognostic (1.75e-1)" "validated prognostic favorable (3.19e-5)" "validated prognostic favorable (1.97e-5)" "unprognostic (9.13e-2)" "unprognostic (2.68e-2)" "unprognostic (9.50e-2)" "unprognostic (4.97e-3)" "unprognostic (1.20e-1)" "unprognostic (4.17e-1)" "unprognostic (1.80e-1)" "unprognostic (2.84e-1)" "unprognostic (8.44e-2)" "unprognostic (1.49e-1)" "unprognostic (8.03e-2)" "unprognostic (1.01e-1)" "unprognostic (9.95e-2)" "unprognostic (4.13e-2)" "unprognostic (1.20e-1)" "unprognostic (7.20e-2)" "unprognostic (3.08e-2)" "unprognostic (1.58e-1)" "unprognostic (3.68e-2)" TPSB2 ENSG00000197253 "Tryptase beta 2" P20231 16 1227272-1230184 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 489 "Mast cells: 13412.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 51 "basophil: 5.0" "Lineage enriched" "Detected in single" 51 "granulocytes: 5.0" "Cancer enriched" "Detected in some" 38 "Leukemia: 59.2" "Adipose subcutaneous - Mast cells, Adipose visceral - Mast cells, Colon - Mast cells, Lung - Mast cells, Minor Salivary Gland - Mast cells, Prostate - Fibroblasts, Skeletal muscle - Macrophages" "HPA049153, HPA049554" Supported "Secreted to blood" Enzyme NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 58: Mast cells - Allergic inflammatory responses" "HPA049153: , HPA049554: " "unprognostic (2.59e-1)" "unprognostic (1.87e-1)" "unprognostic (5.64e-2)" "unprognostic (3.06e-3)" "unprognostic (2.45e-1)" "unprognostic (2.88e-2)" "unprognostic (3.43e-3)" "unprognostic (3.50e-3)" "unprognostic (2.59e-1)" "validated prognostic favorable (6.48e-8)" "validated prognostic favorable (3.57e-5)" "unprognostic (1.02e-1)" "unprognostic (6.37e-2)" "unprognostic (1.62e-1)" "potential prognostic favorable (2.96e-4)" "unprognostic (1.39e-1)" "unprognostic (3.40e-2)" "unprognostic (6.61e-2)" "unprognostic (7.99e-2)" "unprognostic (1.46e-1)" "unprognostic (3.60e-1)" "unprognostic (1.63e-1)" "unprognostic (9.46e-3)" "unprognostic (1.09e-1)" "unprognostic (2.45e-2)" "unprognostic (2.88e-1)" "unprognostic (8.39e-2)" "unprognostic (2.86e-2)" "unprognostic (3.10e-1)" "unprognostic (1.68e-1)" TPSD1 ENSG00000095917 "Tryptase delta 1" Q9BZJ3 16 1256059-1259008 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 20.0" "Cell type enriched" "Detected in some" 29 "Mast cells: 136.1" "Group enriched" "Detected in some" 4 "astrocyte: 2.0;Bergmann glia: 2.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 29 "basophil: 2.9" "Lineage enriched" "Detected in single" 29 "granulocytes: 2.9" "Cancer enriched" "Detected in single" 44 "Leukemia: 24.0" "Adipose subcutaneous - Mast cells, Adipose visceral - Mast cells, Colon - Mast cells" "CAB002215, CAB032871, HPA040182, HPA049554" Supported "Intracellular and membrane" Enzyme NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 58: Mast cells - Allergic inflammatory responses" "CAB002215: , CAB032871: , HPA040182: , HPA049554: " "unprognostic (2.06e-1)" "unprognostic (1.15e-1)" "unprognostic (2.70e-2)" "unprognostic (2.17e-1)" "unprognostic (1.19e-1)" "unprognostic (1.77e-1)" "unprognostic (1.19e-3)" "validated prognostic favorable (5.56e-7)" "validated prognostic favorable (1.73e-4)" "unprognostic (1.36e-1)" "unprognostic (7.53e-3)" "unprognostic (3.36e-2)" "unprognostic (4.94e-2)" "unprognostic (1.56e-1)" "unprognostic (1.51e-1)" "unprognostic (3.62e-1)" "unprognostic (2.63e-1)" "unprognostic (1.02e-1)" "unprognostic (3.47e-2)" "unprognostic (1.62e-1)" "unprognostic (8.04e-2)" "unprognostic (7.01e-2)" "unprognostic (1.31e-2)" "unprognostic (2.71e-2)" TPSG1 "PRSS31, TMT" ENSG00000116176 "Tryptase gamma 1" Q9NRR2 16 1221651-1225268 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 13.6" "Cell type enriched" "Detected in some" 8 "Goblet cells: 269.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Colon Adenocarcinoma (TCGA): 7.3" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney cancer: 2.6" "Minor Salivary Gland - Mast cells" "Not detected" "Not detected" HPA060458 Enhanced NA NA "Cluster 77: Intestine - Digestion" "Cluster 33: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 70: Intestinal goblet cells - Mucin production" 2 "HPA060458: " "unprognostic (1.19e-1)" "unprognostic (3.26e-1)" "potential prognostic favorable (5.03e-4)" "unprognostic (2.32e-2)" "potential prognostic unfavorable (3.42e-4)" "unprognostic (3.82e-3)" "unprognostic (5.61e-2)" "potential prognostic favorable (5.66e-5)" "unprognostic (2.79e-2)" "potential prognostic unfavorable (6.41e-4)" "unprognostic (1.04e-1)" TPST1 TANGO13A ENSG00000169902 "Tyrosylprotein sulfotransferase 1" O60507 7 66205317-66420543 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Neutrophils: 2758.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 82.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 52.5;neutrophil: 35.4" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Prostate - Fibroblasts, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047415, HPA061837" Approved Supported "Golgi apparatus" "Intracellular and membrane" Enzyme NA NA 8900 "Cluster 20: Non-specific - DNA binding" "Cluster 36: Brain & Liver - Signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 72: Neuronal - Signal transduction" "Cluster 24: Neutrophils - Innate immunity signal integration" 3 "Golgi apparatus" "HPA047415: , HPA061837: " "unprognostic (2.30e-1)" "unprognostic (1.20e-1)" "unprognostic (3.11e-1)" "unprognostic (3.82e-2)" "unprognostic (7.49e-2)" "unprognostic (2.62e-1)" "unprognostic (3.52e-2)" "unprognostic (2.42e-1)" "unprognostic (1.37e-2)" "unprognostic (5.34e-3)" "unprognostic (1.05e-2)" "unprognostic (1.95e-1)" "unprognostic (3.41e-2)" "unprognostic (1.41e-1)" "unprognostic (1.68e-2)" "unprognostic (5.49e-2)" "unprognostic (2.77e-3)" "unprognostic (1.08e-1)" "unprognostic (2.06e-2)" "unprognostic (1.19e-2)" "unprognostic (4.51e-1)" "unprognostic (1.12e-1)" "unprognostic (4.69e-2)" "unprognostic (2.47e-1)" "unprognostic (9.56e-2)" "unprognostic (7.57e-3)" "unprognostic (2.39e-1)" "potential prognostic unfavorable (2.40e-4)" "unprognostic (2.00e-1)" "unprognostic (1.15e-2)" "unprognostic (1.71e-2)" TPST2 TANGO13B ENSG00000128294 "Tyrosylprotein sulfotransferase 2" O60704 22 26521996-26596717 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 378.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 245.4;Epididymal principal cells: 360.4;Neutrophils: 281.3;Pancreatic acinar cells: 337.5;Platelets: 1201.6" "Cell type enhanced" "Detected in all" "endothelial cell: 200.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Macrophages, Liver - Hepatocytes, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021054 Enhanced "Intracellular and membrane" Enzyme NA NA 40000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 8: Pancreas - Proteolysis" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 47: Platelets - Hemostasis" 44 "HPA021054: " "unprognostic (9.14e-2)" "unprognostic (4.40e-1)" "unprognostic (1.74e-1)" "unprognostic (3.21e-2)" "unprognostic (3.46e-1)" "unprognostic (9.01e-2)" "unprognostic (1.87e-1)" "unprognostic (2.77e-1)" "unprognostic (8.24e-2)" "unprognostic (1.20e-1)" "potential prognostic unfavorable (3.71e-6)" "unprognostic (4.41e-2)" "potential prognostic unfavorable (6.68e-6)" "unprognostic (2.79e-3)" "unprognostic (3.96e-1)" "unprognostic (3.59e-2)" "unprognostic (4.75e-1)" "unprognostic (1.07e-1)" "unprognostic (1.51e-1)" "unprognostic (1.43e-1)" "unprognostic (7.04e-2)" "unprognostic (1.85e-1)" "potential prognostic unfavorable (1.09e-4)" "unprognostic (3.27e-2)" "unprognostic (8.75e-2)" "unprognostic (5.63e-3)" "unprognostic (5.28e-3)" "unprognostic (3.00e-1)" "unprognostic (4.24e-2)" "unprognostic (4.21e-2)" "potential prognostic favorable (8.15e-4)" TPT1 "fortilin, TCTP" ENSG00000133112 "Tumor protein, translationally-controlled 1" P13693 13 45333471-45341284 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 21778.2" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 28843.4;Pancreatic acinar cells: 14447.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008364, HPA039437, HPA073929" Approved Supported Cytosol NA NA 2900000 "Cluster 11: T-cells - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 80 Cytosol "CAB008364: , HPA039437: , HPA073929: " "unprognostic (7.18e-2)" "unprognostic (2.91e-3)" "unprognostic (5.91e-2)" "unprognostic (2.61e-1)" "unprognostic (6.83e-2)" "unprognostic (2.08e-2)" "unprognostic (3.62e-1)" "unprognostic (9.27e-2)" "unprognostic (1.45e-3)" "unprognostic (2.13e-2)" "validated prognostic favorable (2.19e-5)" "validated prognostic favorable (5.98e-5)" "unprognostic (1.47e-1)" "unprognostic (3.49e-2)" "unprognostic (5.49e-3)" "unprognostic (3.44e-1)" "unprognostic (1.31e-1)" "unprognostic (1.56e-1)" "unprognostic (1.68e-2)" "unprognostic (1.35e-3)" "unprognostic (2.84e-3)" "unprognostic (4.15e-2)" "unprognostic (8.41e-2)" "unprognostic (1.05e-1)" "unprognostic (1.03e-1)" "unprognostic (2.14e-2)" "unprognostic (1.67e-2)" "unprognostic (9.62e-2)" "unprognostic (3.07e-1)" "unprognostic (4.00e-2)" "unprognostic (1.37e-1)" TPTE "CT44, PTEN2" ENSG00000274391 "Transmembrane phosphatase with tensin homology" P56180 21 10521553-10606140 "Enzymes, Plasma proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 191 "testis: 105.6" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 2.0;Distal convoluted tubule cells: 2.3;Early primary spermatocytes: 16.0;Late primary spermatocytes: 4.4;Loop of henle epithelial cells: 2.8;Podocytes: 3.1;Renal collecting duct intercalated cells: 1.9;Renal collecting duct principal cells: 1.6;Renal connecting tubule cells: 1.8;Sertoli cells: 1.4;Undifferentiated spermatogonia: 2.7" "Low cell type specificity" "Detected in some" "Cancer enriched" "Detected in some" 5 "Testicular Germ Cell Tumor (TCGA): 6.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 7.7" "Testis - Spermatocytes" "HPA049690, HPA068342" Enhanced Approved "Endoplasmic reticulum,Cytosol" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 3: Early primary spermatocytes - Early meiosis" 30 Cytosol "Endoplasmic reticulum" "HPA049690: , HPA068342: " "unprognostic (4.72e-2)" "unprognostic (1.32e-1)" "unprognostic (7.55e-2)" TPTE2 TPIP ENSG00000132958 "Transmembrane phosphoinositide 3-phosphatase and tensin homolog 2" Q6XPS3 13 19422876-19561625 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 13 "testis: 6.9" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 25.1;Early primary spermatocytes: 134.5;Early spermatids: 29.5;Late primary spermatocytes: 113.2;Plasma cells: 36.2;Sertoli cells: 27.2;Undifferentiated spermatogonia: 26.8" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in single" 7 "Testicular Germ Cell Tumor (TCGA): 2.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 25 "Bone cancer: 22.3" "Testis - Early spermatids" "Not detected" "Not detected" HPA068342 Approved "Endoplasmic reticulum,Cytosol" NA NA "Cluster 67: Testis - Mixed function" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 3: Early primary spermatocytes - Early meiosis" 9 Cytosol "Endoplasmic reticulum" "HPA068342: " "unprognostic (2.27e-2)" "unprognostic (3.34e-1)" TPTEP2-CSNK1E ENSG00000283900 "TPTEP2-CSNK1E readthrough" 22 38291918-38398522 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 159.8;Esophageal apical cells: 407.6;Loop of henle epithelial cells: 146.4;Papillary tip epithelial cells: 69.1;Podocytes: 100.4;Proximal tubule cells: 93.3;Renal collecting duct intercalated cells: 87.3;Renal collecting duct principal cells: 120.2;Renal connecting tubule cells: 114.9" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 13.6" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Myeloma: 25.0" HPA026288 Uncertain NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 40: Non-specific - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 84: Apical squamous epithelium - Cornification" "HPA026288: " "unprognostic (3.11e-1)" "unprognostic (1.21e-2)" "potential prognostic favorable (4.29e-4)" "unprognostic (1.36e-2)" "unprognostic (6.80e-2)" TPX2 "C20orf1, C20orf2, DIL-2, FLS353, HCA519, p100" ENSG00000088325 "TPX2 microtubule nucleation factor" Q9ULW0 20 31739271-31801805 "Cancer-related genes, Essential proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Mitosis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 45.3;lymphoid tissue: 65.5;testis: 28.7" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 71.5;Early primary spermatocytes: 120.7;Enteric transient amplifying cells: 61.4;Erythrocyte progenitors: 227.3;Esophageal basal cells: 64.2;Extravillous trophoblasts: 86.7;Gastric progenitor cells: 64.1;Late primary spermatocytes: 66.4;Megakaryocyte progenitors: 157.6;Monocyte progenitors: 274.1;Neutrophil progenitors: 112.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 8.1" "Group enriched" "Detected in many" 5 "granulocytes: 5.0;NK-cells: 3.6;T-cells: 8.1" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005487 Enhanced Supported "Nucleoplasm,Cytokinetic bridge,Mitotic spindle" Yes Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 53: Neurons - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 27: Non-specific - Cell proliferation" 24 Nucleoplasm "Cytokinetic bridge, Mitotic spindle" "HPA005487: " "unprognostic (1.09e-2)" "unprognostic (1.23e-1)" "unprognostic (4.47e-2)" "unprognostic (6.19e-2)" "unprognostic (9.47e-2)" "unprognostic (4.78e-2)" "unprognostic (3.16e-1)" "unprognostic (4.14e-2)" "unprognostic (3.06e-1)" "potential prognostic unfavorable (1.64e-5)" "validated prognostic unfavorable (5.19e-9)" "validated prognostic unfavorable (4.20e-8)" "potential prognostic unfavorable (4.73e-13)" "validated prognostic unfavorable (4.31e-7)" "validated prognostic unfavorable (2.38e-10)" "validated prognostic unfavorable (1.66e-5)" "validated prognostic unfavorable (8.22e-4)" "unprognostic (1.43e-2)" "unprognostic (7.24e-3)" "unprognostic (1.44e-1)" "unprognostic (6.74e-2)" "validated prognostic unfavorable (1.36e-5)" "validated prognostic unfavorable (7.35e-4)" "unprognostic (6.46e-2)" "unprognostic (4.71e-2)" "unprognostic (2.05e-2)" "unprognostic (4.14e-2)" "unprognostic (4.78e-2)" "unprognostic (3.51e-1)" "unprognostic (3.29e-2)" "unprognostic (6.83e-2)" TRA2A "AWMS1, htra-2-alpha" ENSG00000164548 "Transformer 2 alpha homolog" Q13595 7 23504780-23532041 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054018 Uncertain Supported Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 15: Bone marrow - Innate immune response" "Cluster 55: Non-specific - Transcription" "Cluster 67: Non-specific - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 49 Nucleoli "Nucleoplasm, Vesicles" "HPA054018: " "unprognostic (7.32e-2)" "unprognostic (8.29e-2)" "unprognostic (1.68e-1)" "unprognostic (1.31e-1)" "unprognostic (1.92e-1)" "unprognostic (1.09e-1)" "unprognostic (1.18e-1)" "unprognostic (1.20e-1)" "unprognostic (3.82e-1)" "unprognostic (5.67e-2)" "unprognostic (1.48e-2)" "unprognostic (4.01e-1)" "unprognostic (9.48e-2)" "potential prognostic unfavorable (1.69e-4)" "unprognostic (4.29e-2)" "unprognostic (1.56e-1)" "unprognostic (2.52e-1)" "potential prognostic favorable (2.44e-4)" "unprognostic (1.70e-1)" "unprognostic (2.05e-1)" "unprognostic (1.79e-1)" "unprognostic (4.54e-3)" "potential prognostic unfavorable (1.08e-4)" "unprognostic (1.79e-1)" "unprognostic (1.73e-1)" "unprognostic (1.65e-1)" "unprognostic (1.26e-1)" "unprognostic (7.37e-2)" "unprognostic (4.37e-1)" "unprognostic (1.97e-1)" "unprognostic (7.94e-2)" TRA2B "Htra2-beta, PPP1R156, SFRS10" ENSG00000136527 "Transformer 2 beta homolog" P62995 3 185914558-185938103 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Activator, Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011692, HPA063597, HPA064972" Supported Enhanced Nucleoplasm NA NA 13000 "Cluster 13: Non-specific - Mitochondria" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 99 Nucleoplasm "CAB011692: , HPA063597: , HPA064972: " "unprognostic (1.68e-2)" "unprognostic (1.99e-1)" "unprognostic (3.28e-2)" "unprognostic (4.56e-2)" "unprognostic (2.18e-2)" "unprognostic (5.56e-2)" "unprognostic (7.34e-2)" "unprognostic (1.95e-2)" "unprognostic (4.84e-2)" "unprognostic (1.13e-2)" "potential prognostic favorable (8.19e-6)" "unprognostic (2.91e-2)" "unprognostic (3.24e-1)" "potential prognostic unfavorable (7.74e-5)" "unprognostic (4.16e-3)" "unprognostic (3.87e-2)" "potential prognostic unfavorable (5.14e-4)" "unprognostic (8.68e-3)" "unprognostic (1.10e-2)" "unprognostic (7.98e-2)" "unprognostic (2.70e-1)" "unprognostic (1.37e-2)" "potential prognostic unfavorable (8.99e-4)" "potential prognostic unfavorable (5.62e-6)" "unprognostic (9.68e-2)" "unprognostic (4.19e-1)" "unprognostic (1.76e-3)" "unprognostic (6.85e-2)" "unprognostic (8.52e-2)" "unprognostic (3.66e-1)" "unprognostic (1.92e-2)" TRABD PP2447 ENSG00000170638 "TraB domain containing" Q9H4I3 22 50185913-50199598 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 198.0;pDCs: 134.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000822 Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 70: Non-specific - Protein processing" "Cluster 15: Non-specific - Transcription" "Cluster 66: Non-specific - Mitochondria" "Cluster 20: Non-specific - Transcription regulation" 17 "Nucleoplasm, Mitochondria" "HPA000822: " "unprognostic (1.67e-1)" "unprognostic (2.19e-1)" "unprognostic (6.50e-3)" "unprognostic (2.80e-1)" "unprognostic (2.42e-1)" "unprognostic (7.18e-2)" "unprognostic (1.73e-1)" "unprognostic (8.37e-3)" "unprognostic (2.74e-1)" "unprognostic (3.77e-1)" "potential prognostic unfavorable (1.95e-5)" "unprognostic (5.25e-2)" "unprognostic (2.13e-2)" "unprognostic (2.67e-3)" "unprognostic (2.09e-2)" "unprognostic (1.05e-1)" "unprognostic (1.02e-1)" "unprognostic (3.24e-2)" "unprognostic (9.46e-2)" "unprognostic (4.71e-3)" "unprognostic (4.20e-2)" "unprognostic (1.75e-3)" "unprognostic (6.72e-2)" "unprognostic (9.83e-2)" "unprognostic (3.13e-2)" "unprognostic (5.17e-2)" "unprognostic (1.59e-1)" "unprognostic (5.66e-3)" "unprognostic (8.30e-2)" "unprognostic (5.82e-2)" "potential prognostic favorable (2.37e-4)" TRABD2A "C2orf89, TIKI1" ENSG00000186854 "TraB domain containing 2A" Q86V40 2 84821650-84907008 "Predicted intracellular proteins, Predicted membrane proteins" "Wnt signaling pathway" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "intestine: 40.2;lymphoid tissue: 10.6;ovary: 38.2" "Cell type enhanced" "Detected in many" "Early spermatids: 609.7;Enteric stem cells: 198.3;Enteric transient amplifying cells: 121.6;Epicardial cells: 448.0;Late primary spermatocytes: 269.2;Late spermatids: 389.9;Ovarian stromal cells: 110.3;Plasma cells: 161.2;Thymocytes: 132.1" "Cell type enhanced" "Detected in many" "deep-layer intratelencephalic: 43.2;endothelial cell: 42.1;leukocyte: 53.0" "Group enriched" "Detected in many" 6 "Colon Adenocarcinoma (TCGA): 66.4;Rectum Adenocarcinoma (TCGA): 65.1" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 72.1" "Lineage enriched" "Detected in many" 18 "T-cells: 72.1" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 63.9;colorectal cancer: 35.7" "Spleen - T-cells, Testis - Early spermatids, Testis - Late spermatids" HPA045817 Approved "Intracellular and membrane" Enzyme NA NA 19000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 77: Intestine - Digestion" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 9: T-cells - Adaptive immunity: Regulation" "HPA045817: " "unprognostic (1.80e-1)" "unprognostic (3.07e-2)" "unprognostic (2.09e-1)" "potential prognostic favorable (8.12e-7)" "unprognostic (1.03e-1)" "unprognostic (9.92e-2)" "unprognostic (3.92e-2)" "unprognostic (4.02e-2)" "unprognostic (4.24e-2)" "unprognostic (3.45e-1)" "unprognostic (5.23e-2)" "unprognostic (1.54e-1)" "unprognostic (2.04e-2)" "unprognostic (2.74e-2)" "unprognostic (1.38e-1)" "unprognostic (8.35e-2)" "unprognostic (4.42e-2)" "unprognostic (1.42e-1)" "unprognostic (5.62e-2)" "unprognostic (5.73e-3)" "unprognostic (1.16e-1)" "unprognostic (1.07e-1)" "unprognostic (5.67e-2)" "unprognostic (5.93e-3)" "unprognostic (6.85e-2)" TRABD2B TIKI2 ENSG00000269113 "TraB domain containing 2B" A6NFA1 1 47760528-47997385 "Predicted intracellular proteins" "Wnt signaling pathway" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 20.3;kidney: 15.0" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 686.9;Loop of henle epithelial cells: 227.9;Papillary tip epithelial cells: 132.0;Pituitary stem cells: 128.3;Proximal tubule cells: 1139.1;Renal collecting duct principal cells: 133.0;Renal connecting tubule cells: 649.6" "Group enriched" "Detected in some" 6 "fibroblast: 54.4;vascular associated smooth muscle cell: 173.3" "Group enriched" "Detected in many" 5 "Kidney Renal Clear Cell Carcinoma (TCGA): 14.7;Kidney Renal Papillary Cell Carcinoma (TCGA): 25.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney cancer: 4.2" "Adipose subcutaneous - Smooth muscle cells, Colon - Enteric glia cells, Spleen - Fibroblasts_2, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA045817, HPA074725" Approved Supported "Nucleoplasm,Plasma membrane" "Intracellular and membrane" Enzyme NA NA 58000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 35: Non-specific - DNA binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 88: Proximal tubular cells - Transmembrane transport" 3 "Plasma membrane" Nucleoplasm "HPA045817: , HPA074725: " "unprognostic (1.79e-2)" "unprognostic (2.39e-1)" "validated prognostic favorable (4.03e-5)" "validated prognostic favorable (6.59e-4)" "unprognostic (6.36e-3)" "unprognostic (1.05e-2)" "unprognostic (1.94e-1)" "unprognostic (3.28e-1)" "unprognostic (3.44e-3)" "unprognostic (3.92e-1)" TRAC ENSG00000277734 "T cell receptor alpha constant" P01848 14 22547506-22552156 "Disease related genes, Predicted membrane proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "lymphoid tissue: 733.6" "Cell type enriched" "Detected in many" 4 "T-cells: 482.1" "Cell type enriched" "Detected in some" 8 "leukocyte: 258.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "MAIT T-cell: 2127.4;memory CD4 T-cell: 2948.4;memory CD8 T-cell: 2508.6;naive CD4 T-cell: 2680.8;naive CD8 T-cell: 2394.9;T-reg: 4391.5" "Lineage enriched" "Detected in all" 41 "T-cells: 4391.5" "Group enriched" "Detected in many" 6 "Leukemia: 132.6;lymphoma: 82.5" "Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Colon - T-cells, Liver - T-cells, Lung - T-cells, Minor Salivary Gland - T-cells, Pancreas - T-cells, Pituitary gland - Corticotropes, Prostate - T-cells, Skeletal muscle - Fibroblasts, Spleen - T-cells, Stomach - T-cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - T-cells" "Low region specificity" "Detected in all" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 54: Immune cells - T cell receptor" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" "potential prognostic favorable (1.79e-4)" "unprognostic (1.68e-3)" "unprognostic (9.55e-3)" "unprognostic (9.75e-2)" "unprognostic (1.15e-1)" "unprognostic (2.49e-2)" "potential prognostic favorable (3.04e-4)" "unprognostic (1.71e-1)" "unprognostic (2.38e-1)" "unprognostic (6.55e-2)" "unprognostic (2.29e-2)" "unprognostic (4.88e-2)" "unprognostic (1.10e-2)" "unprognostic (1.37e-1)" "unprognostic (6.42e-2)" "unprognostic (3.22e-1)" "unprognostic (3.34e-2)" "unprognostic (4.81e-2)" "unprognostic (1.99e-1)" "unprognostic (8.44e-2)" "unprognostic (1.51e-2)" "unprognostic (6.72e-3)" "unprognostic (6.38e-2)" "unprognostic (5.36e-2)" "unprognostic (3.07e-2)" "unprognostic (8.61e-3)" TRADD Hs.89862 ENSG00000102871 "TNFRSF1A associated via death domain" Q15628 16 67154185-67159909 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 141.2;Esophageal suprabasal cells: 125.4" "Cell type enhanced" "Detected in many" "leukocyte: 26.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004602, HPA071341" Enhanced Approved Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 5: Spleen - Immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 67: Plasma cells - Plasma cell differentiation" 27 Cytosol "CAB004602: , HPA071341: " "unprognostic (2.19e-2)" "unprognostic (6.83e-2)" "unprognostic (5.73e-2)" "unprognostic (4.45e-2)" "unprognostic (2.36e-2)" "unprognostic (4.20e-3)" "unprognostic (9.39e-3)" "potential prognostic unfavorable (4.58e-4)" "unprognostic (5.71e-2)" "unprognostic (7.29e-3)" "unprognostic (9.72e-3)" "unprognostic (4.72e-1)" "potential prognostic favorable (2.44e-4)" "unprognostic (3.59e-2)" "unprognostic (2.42e-2)" "unprognostic (9.57e-2)" "unprognostic (3.16e-1)" "potential prognostic unfavorable (6.95e-4)" "unprognostic (1.76e-2)" "unprognostic (2.79e-1)" "unprognostic (1.90e-1)" "unprognostic (1.86e-1)" "unprognostic (1.26e-1)" "unprognostic (2.71e-2)" "unprognostic (5.08e-2)" "unprognostic (1.44e-2)" "unprognostic (7.62e-2)" "unprognostic (1.07e-1)" "unprognostic (5.32e-2)" "unprognostic (2.75e-1)" "unprognostic (6.55e-2)" TRAF1 EBI6 ENSG00000056558 "TNF receptor associated factor 1" Q13077 9 120902393-120929173 "Cancer-related genes, Predicted intracellular proteins" Apoptosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "cDC: 348.6;Epididymal basal cells: 72.1;Macrophages: 88.0;Mast cells: 53.3;monocytes: 238.6;Neutrophils: 136.8;NK-cells: 78.8;T-cells: 113.3" "Cell type enriched" "Detected in all" 4 "leukocyte: 77.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 13.0" "Lineage enriched" "Detected in many" 4 "T-cells: 13.0" "Cancer enhanced" "Detected in many" "lymphoma: 43.9" "Stomach - Fibroblasts, Thyroid gland - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001852, CAB009593" Enhanced Approved Nucleoplasm NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 11: White matter - Signal transduction" "Cluster 55: Lymphoma - Immune response" "Cluster 82: Dendritic cells - Antigen presentation" 240 Nucleoplasm "CAB009593: , HPA001852: " "unprognostic (4.37e-2)" "unprognostic (1.80e-3)" "potential prognostic favorable (5.75e-4)" "unprognostic (1.84e-1)" "unprognostic (4.26e-3)" "unprognostic (3.92e-1)" "unprognostic (1.61e-2)" "unprognostic (2.49e-2)" "potential prognostic favorable (8.79e-4)" "unprognostic (1.87e-1)" "unprognostic (4.59e-2)" "unprognostic (7.47e-2)" "unprognostic (1.07e-1)" "unprognostic (1.63e-1)" "unprognostic (5.21e-3)" "unprognostic (1.01e-1)" "unprognostic (5.17e-2)" "unprognostic (1.02e-1)" "unprognostic (2.61e-1)" "unprognostic (3.12e-1)" "unprognostic (2.34e-3)" "potential prognostic favorable (2.11e-4)" "potential prognostic unfavorable (2.51e-4)" "unprognostic (2.06e-1)" "unprognostic (2.18e-1)" "unprognostic (5.57e-3)" "unprognostic (1.47e-2)" "unprognostic (8.27e-3)" "unprognostic (2.26e-3)" "unprognostic (2.18e-1)" "unprognostic (3.37e-1)" TRAF2 "RNF117, TRAP3" ENSG00000127191 "TNF receptor associated factor 2" Q12933 9 136881912-136926607 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 56.6;Oocytes: 96.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004603, HPA009972, HPA010634" Uncertain Enhanced Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 64: Non-specific - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 65: Non-specific - Cell growth & division" 420 Cytosol "CAB004603: , HPA009972: , HPA010634: " "unprognostic (1.80e-2)" "unprognostic (1.36e-2)" "unprognostic (1.49e-1)" "unprognostic (1.81e-2)" "unprognostic (1.55e-2)" "unprognostic (1.59e-3)" "unprognostic (1.82e-2)" "unprognostic (2.73e-3)" "unprognostic (1.94e-1)" "unprognostic (6.84e-2)" "unprognostic (8.65e-2)" "unprognostic (1.21e-1)" "unprognostic (3.55e-1)" "potential prognostic unfavorable (1.28e-4)" "unprognostic (2.60e-2)" "potential prognostic unfavorable (8.19e-4)" "unprognostic (1.02e-1)" "unprognostic (4.59e-2)" "unprognostic (1.92e-1)" "unprognostic (2.72e-2)" "unprognostic (3.81e-3)" "unprognostic (7.35e-2)" "unprognostic (8.86e-2)" "unprognostic (2.89e-2)" "unprognostic (1.30e-2)" "unprognostic (9.38e-3)" "unprognostic (2.89e-2)" "unprognostic (2.48e-3)" "unprognostic (2.26e-1)" "unprognostic (5.56e-3)" "unprognostic (2.01e-1)" TRAF3 "CAP-1, CD40bp, CRAF1, LAP1, RNF118" ENSG00000131323 "TNF receptor associated factor 3" Q13114 14 102777449-102911500 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Immunity, Ubl conjugation pathway" Transferase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 397.1;Neutrophils: 582.3;Plasma cells: 528.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002933 Uncertain NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 29: Forebrain - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 120 "HPA002933: " "unprognostic (3.94e-1)" "unprognostic (2.49e-1)" "unprognostic (3.10e-2)" "unprognostic (4.91e-2)" "unprognostic (7.33e-2)" "unprognostic (4.72e-2)" "unprognostic (9.16e-2)" "unprognostic (1.96e-3)" "unprognostic (1.12e-1)" "unprognostic (2.56e-2)" "unprognostic (7.96e-2)" "unprognostic (6.94e-2)" "unprognostic (1.27e-1)" "potential prognostic unfavorable (6.40e-5)" "unprognostic (2.24e-1)" "unprognostic (5.50e-2)" "unprognostic (1.73e-1)" "unprognostic (2.38e-1)" "unprognostic (1.82e-1)" "unprognostic (7.12e-2)" "unprognostic (9.98e-2)" "unprognostic (1.02e-1)" "unprognostic (2.39e-2)" "unprognostic (1.42e-1)" "unprognostic (4.17e-2)" "unprognostic (3.17e-2)" "unprognostic (3.11e-2)" "unprognostic (1.22e-1)" "unprognostic (4.97e-2)" "unprognostic (7.10e-3)" "unprognostic (1.89e-1)" TRAF3IP1 "DKFZP434F124, FAP116, IFT54, MIP-T3, MIPT3" ENSG00000204104 "TRAF3 interacting protein 1" Q8TDR0 2 238320441-238400897 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Leber congenital amaurosis, Nephronophthisis, Senior-Loken syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 356.5;Ependymal cells: 186.0;Fallopian tube ciliated cells: 344.3;Respiratory ciliated cells: 474.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 2.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037857, HPA037858" Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Nuclear bodies,Primary cilium transition zone" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 107: Ciliated cells - Cilia assembly & function" 32 "Nuclear bodies, Primary cilium transition zone" "Nucleoplasm, Nucleoli fibrillar center" "HPA037857: , HPA037858: " "unprognostic (5.10e-2)" "unprognostic (1.80e-1)" "unprognostic (3.08e-2)" "unprognostic (2.88e-1)" "unprognostic (6.58e-2)" "potential prognostic favorable (2.44e-4)" "unprognostic (1.54e-1)" "unprognostic (7.16e-3)" "unprognostic (1.46e-1)" "unprognostic (2.61e-1)" "potential prognostic favorable (1.30e-5)" "unprognostic (3.98e-3)" "unprognostic (2.21e-1)" "unprognostic (6.91e-3)" "unprognostic (2.23e-2)" "unprognostic (8.37e-2)" "unprognostic (1.47e-1)" "unprognostic (2.66e-1)" "unprognostic (1.35e-2)" "unprognostic (4.85e-2)" "unprognostic (1.33e-1)" "unprognostic (3.52e-2)" "unprognostic (9.15e-3)" "unprognostic (1.08e-2)" "unprognostic (1.11e-2)" "unprognostic (6.42e-3)" "unprognostic (2.44e-2)" "unprognostic (1.84e-1)" "unprognostic (9.06e-2)" "unprognostic (5.84e-2)" "unprognostic (1.33e-1)" TRAF3IP2 "ACT1, C6orf2, C6orf4, C6orf5, C6orf6, CIKS, DKFZP586G0522" ENSG00000056972 "TRAF3 interacting protein 2" O43734 6 111555381-111606906 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Inflammatory response, Ubl conjugation pathway" Transferase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal basal cells: 279.2;Esophageal apical cells: 123.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 25.9" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA036352 Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 35: RS4;11 - Unknown function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 19 "Golgi apparatus" Vesicles "HPA036352: " "unprognostic (1.43e-1)" "unprognostic (8.04e-2)" "unprognostic (8.04e-2)" "unprognostic (1.37e-3)" "unprognostic (2.18e-2)" "unprognostic (2.29e-2)" "unprognostic (1.65e-1)" "unprognostic (1.24e-1)" "unprognostic (6.11e-2)" "unprognostic (3.05e-2)" "unprognostic (7.24e-2)" "unprognostic (8.72e-3)" "unprognostic (7.89e-2)" "unprognostic (2.49e-3)" "unprognostic (2.56e-3)" "unprognostic (1.31e-1)" "unprognostic (2.33e-1)" "unprognostic (1.79e-1)" "unprognostic (1.33e-2)" "unprognostic (2.92e-2)" "unprognostic (3.92e-2)" "unprognostic (5.42e-2)" "unprognostic (2.28e-1)" "unprognostic (2.39e-2)" "unprognostic (2.74e-1)" "unprognostic (4.67e-2)" "unprognostic (3.50e-2)" "unprognostic (7.73e-2)" "unprognostic (8.99e-3)" "unprognostic (6.91e-3)" "unprognostic (4.14e-3)" TRAF3IP3 T3JAM ENSG00000009790 "TRAF3 interacting protein 3" Q9Y228 1 209756032-209782320 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 121.5" "Cell type enhanced" "Detected in many" "B-cells: 136.9;Endometrial luminal cells: 142.2;Innate lymphoid cells: 88.8;Mast cells: 102.9;Microglia: 137.5;monocytes: 80.8;Neutrophil progenitors: 152.8;Neutrophils: 326.2;NK-cells: 177.2;pDCs: 83.7;Plasma cells: 67.9;T-cells: 179.8;Thymocytes: 116.0" "Group enriched" "Detected in many" 57 "central nervous system macrophage: 162.7;leukocyte: 265.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 17 "Leukemia: 48.6;lymphoma: 38.1;Myeloma: 70.7" "Adipose subcutaneous - T-cells, Adrenal gland - T-cells, Heart muscle - T-cells, Liver - T-cells, Minor Salivary Gland - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Stomach - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA040796 Enhanced Uncertain Vesicles NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 66 Vesicles "HPA040796: " "unprognostic (2.38e-3)" "potential prognostic favorable (3.08e-5)" "unprognostic (1.44e-2)" "unprognostic (4.43e-2)" "unprognostic (4.21e-2)" "unprognostic (1.79e-1)" "unprognostic (5.03e-2)" "unprognostic (8.77e-2)" "potential prognostic favorable (5.44e-4)" "unprognostic (1.01e-1)" "unprognostic (1.78e-1)" "unprognostic (5.46e-2)" "unprognostic (3.45e-2)" "unprognostic (1.98e-2)" "unprognostic (8.15e-3)" "potential prognostic favorable (7.52e-4)" "unprognostic (2.30e-1)" "unprognostic (1.22e-1)" "unprognostic (2.90e-1)" "unprognostic (2.05e-1)" "unprognostic (2.20e-1)" "unprognostic (1.05e-1)" "unprognostic (1.41e-1)" "unprognostic (1.25e-1)" "unprognostic (1.58e-2)" "unprognostic (1.31e-1)" "unprognostic (9.04e-2)" "unprognostic (1.40e-1)" "unprognostic (3.84e-2)" "unprognostic (4.19e-2)" "unprognostic (2.63e-1)" TRAF4 "CART1, MLN62, RNF83" ENSG00000076604 "TNF receptor associated factor 4" Q9BUZ4 17 28744011-28750956 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters" "Apoptosis, Immunity, Innate immunity, Ubl conjugation pathway" "Developmental protein, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast secretory cells: 161.3;Epididymal basal cells: 225.7;Extravillous trophoblasts: 169.6;pDCs: 177.1;Urothelial cells: 225.7" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 47.7;oligodendrocyte precursor cell: 87.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "plasmacytoid DC: 43.0" "Lineage enriched" "Detected in many" 5 "dendritic cells: 43.0" "Low cancer specificity" "Detected in all" "Kidney - Macrophages, Minor Salivary Gland - Minor salivary glandular cells, Spleen - B-cells (Spleen), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009055, HPA021904, HPA052377" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 60: Stomach - Digestion" "Cluster 11: White matter - Signal transduction" "Cluster 55: Lymphoma - Immune response" "Cluster 69: Urothelial cells - Basic cellular functions" 119 "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "CAB009055: , HPA021904: , HPA052377: " "unprognostic (3.96e-2)" "unprognostic (1.65e-2)" "unprognostic (7.68e-2)" "unprognostic (6.46e-2)" "unprognostic (7.08e-2)" "unprognostic (2.47e-1)" "unprognostic (1.47e-1)" "unprognostic (5.01e-2)" "unprognostic (9.81e-3)" "unprognostic (1.89e-1)" "unprognostic (1.23e-2)" "unprognostic (8.44e-2)" "unprognostic (1.94e-2)" "unprognostic (1.39e-3)" "unprognostic (7.48e-3)" "unprognostic (3.92e-2)" "unprognostic (4.79e-2)" "unprognostic (2.60e-1)" "unprognostic (3.78e-3)" "unprognostic (1.21e-1)" "unprognostic (1.39e-2)" "unprognostic (2.52e-2)" "unprognostic (5.43e-2)" "unprognostic (2.29e-1)" "unprognostic (1.13e-2)" "potential prognostic favorable (3.65e-4)" "unprognostic (5.64e-3)" "unprognostic (6.81e-2)" "unprognostic (2.03e-1)" "unprognostic (9.28e-2)" "unprognostic (3.43e-1)" TRAF5 RNF84 ENSG00000082512 "TNF receptor associated factor 5" O00463 1 211326615-211374946 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "B-cells: 159.4;Choroid plexus epithelial cells: 163.4;Mast cells: 96.1;Podocytes: 110.7;Thymocytes: 122.0;Tuft cells: 103.8" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 159.8" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "choroid plexus: 55.4" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Smooth muscle cells, Spleen - B-cells (Spleen), Thyroid gland - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008052, CAB010277" Enhanced Supported Centrosome,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 23: Choroid plexus - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 64 Cytosol Centrosome "CAB010277: , HPA008052: " "unprognostic (1.05e-1)" "unprognostic (6.39e-2)" "unprognostic (2.54e-2)" "unprognostic (1.24e-2)" "unprognostic (6.78e-2)" "unprognostic (3.70e-2)" "unprognostic (8.47e-2)" "unprognostic (2.41e-2)" "unprognostic (2.86e-2)" "unprognostic (1.07e-1)" "unprognostic (1.44e-1)" "unprognostic (1.08e-1)" "unprognostic (2.88e-2)" "unprognostic (1.88e-3)" "unprognostic (1.67e-1)" "unprognostic (3.59e-2)" "unprognostic (1.23e-1)" "unprognostic (3.73e-1)" "unprognostic (2.00e-2)" "unprognostic (8.18e-3)" "unprognostic (1.42e-2)" "unprognostic (6.10e-2)" "unprognostic (3.35e-2)" "unprognostic (1.24e-1)" "unprognostic (2.59e-1)" "unprognostic (5.96e-2)" "unprognostic (1.99e-1)" "unprognostic (3.03e-1)" "unprognostic (5.84e-2)" "unprognostic (7.87e-2)" "unprognostic (1.67e-1)" TRAF6 RNF85 ENSG00000175104 "TNF receptor associated factor 6" Q9Y4K3 11 36483769-36510272 "Enzymes, Predicted intracellular proteins" "DNA damage, Immunity, Osteogenesis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004605, HPA019805, HPA020599" Approved Uncertain Nucleoli,Mitochondria NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 15: Bone marrow - Innate immune response" "Cluster 34: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 82: Dendritic cells - Antigen presentation" 249 Mitochondria Nucleoli "CAB004605: , HPA019805: , HPA020599: " "unprognostic (3.15e-2)" "unprognostic (1.36e-1)" "unprognostic (1.07e-1)" "unprognostic (7.45e-2)" "unprognostic (2.71e-1)" "unprognostic (2.12e-1)" "unprognostic (1.41e-1)" "unprognostic (1.07e-1)" "unprognostic (1.15e-1)" "unprognostic (2.84e-2)" "validated prognostic favorable (1.73e-8)" "validated prognostic favorable (3.24e-5)" "unprognostic (9.26e-3)" "unprognostic (6.45e-2)" "unprognostic (1.35e-1)" "unprognostic (1.62e-1)" "unprognostic (2.94e-1)" "unprognostic (2.29e-1)" "unprognostic (5.20e-2)" "unprognostic (5.18e-2)" "unprognostic (3.48e-3)" "potential prognostic unfavorable (4.19e-4)" "unprognostic (5.08e-2)" "unprognostic (1.84e-1)" "potential prognostic favorable (7.16e-4)" "unprognostic (3.95e-1)" "unprognostic (1.07e-1)" "unprognostic (6.86e-2)" "unprognostic (2.22e-1)" "unprognostic (7.28e-2)" "unprognostic (2.54e-1)" TRAF7 "DKFZp586I021, MGC7807, RFWD1, RNF119" ENSG00000131653 "TNF receptor associated factor 7" Q6Q0C0 16 2155698-2178129 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation, Ubl conjugation pathway" Transferase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 105.1;Esophageal suprabasal cells: 88.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040935, HPA041229" Approved Supported Vesicles NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 64: Non-specific - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 54: Non-specific - Transcription" "Cluster 85: Squamous epithelial cells - Keratinization" 36 Vesicles "HPA040935: , HPA041229: " "unprognostic (4.74e-2)" "unprognostic (3.33e-1)" "unprognostic (3.12e-1)" "unprognostic (9.10e-3)" "unprognostic (2.04e-1)" "unprognostic (1.20e-1)" "unprognostic (6.38e-2)" "unprognostic (2.87e-2)" "unprognostic (6.11e-2)" "unprognostic (2.06e-1)" "unprognostic (7.18e-3)" "potential prognostic unfavorable (7.21e-6)" "unprognostic (4.84e-2)" "potential prognostic unfavorable (1.77e-4)" "unprognostic (1.86e-3)" "unprognostic (3.66e-3)" "unprognostic (5.35e-3)" "unprognostic (4.47e-2)" "unprognostic (5.53e-2)" "unprognostic (3.15e-3)" "unprognostic (5.42e-2)" "unprognostic (2.62e-2)" "unprognostic (2.23e-1)" "unprognostic (2.90e-2)" "unprognostic (3.19e-1)" "unprognostic (6.17e-2)" "unprognostic (9.97e-2)" "unprognostic (1.79e-1)" "unprognostic (1.55e-1)" "unprognostic (1.94e-2)" "unprognostic (1.07e-1)" TRAFD1 FLN29 ENSG00000135148 "TRAF-type zinc finger domain containing 1" O14545 12 112125538-112153604 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 115.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Skin - Keratinocyte (other), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039254, HPA039266" Enhanced Approved "Nucleoplasm,Actin filaments,Focal adhesion sites,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 58: Skin - Keratinization" "Cluster 30: White matter - Myelination" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 8 Nucleoplasm "Actin filaments, Focal adhesion sites, Cytosol" "HPA039254: , HPA039266: " "unprognostic (3.89e-2)" "unprognostic (2.07e-1)" "unprognostic (3.39e-1)" "unprognostic (1.36e-2)" "unprognostic (1.08e-1)" "unprognostic (6.44e-2)" "unprognostic (2.34e-1)" "potential prognostic favorable (7.61e-4)" "unprognostic (8.46e-2)" "unprognostic (4.89e-2)" "unprognostic (3.43e-2)" "unprognostic (1.12e-1)" "unprognostic (1.62e-1)" "unprognostic (1.29e-3)" "unprognostic (1.16e-1)" "unprognostic (6.16e-2)" "unprognostic (1.08e-3)" "unprognostic (1.53e-1)" "unprognostic (7.74e-2)" "unprognostic (2.37e-1)" "unprognostic (2.07e-2)" "unprognostic (2.58e-1)" "unprognostic (4.74e-2)" "unprognostic (3.05e-1)" "unprognostic (1.39e-1)" "unprognostic (7.85e-2)" "unprognostic (3.40e-1)" "unprognostic (1.51e-1)" "unprognostic (2.09e-1)" "unprognostic (2.97e-2)" "unprognostic (6.63e-2)" TRAIP "RNF206, TRIP" ENSG00000183763 "TRAF interacting protein" Q9BWF2 3 49828601-49856574 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 13.7;Early primary spermatocytes: 17.5;Erythrocyte progenitors: 11.0;Extravillous trophoblasts: 10.7;Late primary spermatocytes: 12.6;Megakaryocyte progenitors: 11.4;Monocyte progenitors: 13.5;Oocytes: 41.4;Paneth cells: 11.6;Retinal amacrine cells: 12.3" "Cell type enhanced" "Detected in many" "medium spiny neuron: 16.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Mitotic cells (Adrenal gland), Kidney - Fibroblasts, Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 14.2" "HPA036261, HPA036262" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 33: Neurons - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Cell proliferation" 20 "Plasma membrane, Cytosol" "HPA036261: , HPA036262: " "unprognostic (8.61e-3)" "unprognostic (7.57e-2)" "unprognostic (7.05e-2)" "unprognostic (6.68e-2)" "unprognostic (1.42e-1)" "unprognostic (1.54e-1)" "unprognostic (1.23e-1)" "unprognostic (3.81e-2)" "unprognostic (1.78e-1)" "unprognostic (7.55e-2)" "validated prognostic unfavorable (6.86e-7)" "validated prognostic unfavorable (6.61e-4)" "unprognostic (5.88e-2)" "validated prognostic unfavorable (6.33e-8)" "validated prognostic unfavorable (9.26e-7)" "potential prognostic unfavorable (2.97e-4)" "unprognostic (8.29e-3)" "unprognostic (1.04e-2)" "unprognostic (1.03e-2)" "unprognostic (6.46e-2)" "unprognostic (1.65e-1)" "unprognostic (8.60e-3)" "potential prognostic unfavorable (9.57e-4)" "unprognostic (2.82e-2)" "unprognostic (2.49e-1)" "unprognostic (7.90e-2)" "unprognostic (3.98e-2)" "unprognostic (4.83e-2)" "unprognostic (3.10e-1)" "unprognostic (8.63e-2)" "unprognostic (9.35e-2)" TRAJ1 ENSG00000211888 "T cell receptor alpha joining 1 (non-functional)" 14 22545037-22545098 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "lymphoid tissue: 26.8;retina: 87.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory CD8 T-cell: 3.7" "Lineage enriched" "Detected in single" 37 "T-cells: 3.7" "Group enriched" "Detected in some" 4 "Leukemia: 6.4;lymphoma: 1.7" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 54: Immune cells - T cell receptor" "Cluster 59: Leukemia - T-cell receptor" "unprognostic (2.52e-1)" "unprognostic (5.80e-1)" "unprognostic (2.54e-2)" "unprognostic (6.02e-2)" "unprognostic (1.24e-1)" "unprognostic (1.69e-2)" "unprognostic (2.01e-1)" TRAJ10 ENSG00000211879 "T cell receptor alpha joining 10" 14 22533497-22533560 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 20.9;retina: 29.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "memory CD4 T-cell: 156.8;memory CD8 T-cell: 239.2;naive CD4 T-cell: 141.4;naive CD8 T-cell: 426.5;T-reg: 230.0" "Lineage enriched" "Detected in many" 23 "T-cells: 426.5" "Group enriched" "Detected in some" 4 "Leukemia: 3.9;lymphoma: 5.9" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 54: Immune cells - T cell receptor" "Cluster 55: Lymphoma - Immune response" "unprognostic (3.27e-1)" "unprognostic (8.35e-2)" "unprognostic (4.70e-1)" "unprognostic (6.89e-1)" "unprognostic (1.91e-1)" "unprognostic (1.09e-1)" TRAJ11 ENSG00000211878 "T cell receptor alpha joining 11" 14 22532502-22532561 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "lymphoid tissue: 9.2;retina: 26.2" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Testicular Germ Cell Tumor (TCGA): 2.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 139.3" "Lineage enriched" "Detected in single" 151 "T-cells: 139.3" "Cancer enhanced" "Detected in single" "lymphoma: 1.3" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 54: Immune cells - T cell receptor" "Cluster 59: Leukemia - T-cell receptor" "unprognostic (1.92e-1)" "unprognostic (2.98e-1)" "unprognostic (3.04e-1)" "unprognostic (6.27e-2)" "unprognostic (1.60e-1)" TRAJ12 ENSG00000211877 "T cell receptor alpha joining 12" 14 22531939-22531998 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 9 "lymphoid tissue: 28.3;retina: 29.0" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Stomach Adenocarcinoma (TCGA): 1.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 321.0" "Group enriched" "Detected in all" 111 "B-cells: 198.0;T-cells: 321.0" "Cancer enriched" "Detected in some" 5 "lymphoma: 16.1" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 54: Immune cells - T cell receptor" "Cluster 55: Lymphoma - Immune response" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (1.72e-1)" "unprognostic (7.46e-2)" "unprognostic (3.87e-2)" "unprognostic (2.29e-1)" "unprognostic (5.77e-2)" "unprognostic (5.32e-2)" "unprognostic (1.39e-1)" TRAJ13 ENSG00000211876 "T cell receptor alpha joining 13" 14 22531076-22531138 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "lymphoid tissue: 14.8;retina: 26.0" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 1.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "memory CD4 T-cell: 83.0;memory CD8 T-cell: 59.1;naive CD4 T-cell: 85.7;naive CD8 T-cell: 48.1;T-reg: 126.6" "Lineage enriched" "Detected in many" 87 "T-cells: 126.6" "Cancer enhanced" "Detected in single" "lymphoma: 1.4" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 54: Immune cells - T cell receptor" "Cluster 59: Leukemia - T-cell receptor" "unprognostic (3.71e-1)" "unprognostic (1.22e-1)" "unprognostic (1.91e-1)" "unprognostic (7.55e-2)" "unprognostic (9.90e-3)" TRAJ14 ENSG00000211875 "T cell receptor alpha joining 14" 14 22530327-22530378 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 4 "lymphoid tissue: 8.0;retina: 20.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "MAIT T-cell: 5.3;memory CD4 T-cell: 7.6;memory CD8 T-cell: 10.2;naive CD4 T-cell: 6.2;naive CD8 T-cell: 3.9;T-reg: 13.8" "Lineage enriched" "Detected in single" 138 "T-cells: 13.8" "Cancer enhanced" "Detected in single" "lymphoma: 1.1" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 54: Immune cells - T cell receptor" "Cluster 59: Leukemia - T-cell receptor" "unprognostic (6.01e-3)" "unprognostic (2.37e-1)" "unprognostic (2.59e-1)" TRAJ16 ENSG00000211873 "T cell receptor alpha joining 16" 14 22528527-22528586 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "intestine: 5.4;lymphoid tissue: 8.2;retina: 16.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 32 "MAIT T-cell: 39.1;memory CD4 T-cell: 55.8;memory CD8 T-cell: 52.7;naive CD4 T-cell: 44.4;naive CD8 T-cell: 37.6;T-reg: 60.3" "Lineage enriched" "Detected in many" 40 "T-cells: 60.3" "Not detected" "Not detected" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 54: Immune cells - T cell receptor" "Cluster 59: Leukemia - T-cell receptor" "unprognostic (2.58e-1)" "unprognostic (2.21e-2)" "unprognostic (1.48e-3)" TRAJ17 ENSG00000211872 "T cell receptor alpha joining 17" 14 22526844-22526906 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 6.8;retina: 14.9" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "Testicular Germ Cell Tumor (TCGA): 4.1" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "T-reg: 148.7" "Lineage enriched" "Detected in many" 31 "T-cells: 148.7" "Not detected" "Not detected" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 54: Immune cells - T cell receptor" "Cluster 59: Leukemia - T-cell receptor" "unprognostic (2.56e-1)" "unprognostic (3.87e-1)" "unprognostic (2.72e-1)" "unprognostic (1.75e-1)" "unprognostic (7.15e-1)" "unprognostic (1.07e-1)" TRAJ18 ENSG00000211871 "T cell receptor alpha joining 18" 14 22525650-22525715 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "lymphoid tissue: 26.3;retina: 14.9" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 2.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory CD4 T-cell: 66.3;memory CD8 T-cell: 37.8;naive CD4 T-cell: 96.6;naive CD8 T-cell: 82.8;T-reg: 105.3" "Lineage enriched" "Detected in many" 6 "T-cells: 105.3" "Group enriched" "Detected in some" 9 "Leukemia: 2.7;lymphoma: 7.1" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 54: Immune cells - T cell receptor" "Cluster 46: Lymphoma - Humoral immune response" "unprognostic (1.77e-1)" "unprognostic (2.79e-1)" "unprognostic (5.82e-1)" "unprognostic (3.05e-1)" "unprognostic (6.03e-1)" "unprognostic (1.77e-1)" "unprognostic (9.14e-2)" TRAJ19 ENSG00000211870 "T cell receptor alpha joining 19 (non-functional)" 14 22525263-22525322 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 4 "lymphoid tissue: 6.9;retina: 19.3" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 8 "Stomach Adenocarcinoma (TCGA): 1.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 1.7;memory CD8 T-cell: 1.7" "Lineage enriched" "Detected in single" 17 "T-cells: 1.7" "Cancer enhanced" "Detected in some" "lymphoma: 1.4;Rhabdoid: 1.0" NA NA "Cluster 27: T-cells - Unknown function" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 54: Immune cells - T cell receptor" "Cluster 59: Leukemia - T-cell receptor" "unprognostic (7.08e-2)" "unprognostic (7.49e-2)" "unprognostic (7.46e-1)" "unprognostic (9.90e-3)" "unprognostic (2.12e-3)" TRAJ2 ENSG00000211887 "T cell receptor alpha joining 2 (non-functional)" 14 22544071-22544136 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "retina: 68.0" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Stomach Adenocarcinoma (TCGA): 1.3" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 1.7;memory CD8 T-cell: 2.7" "Lineage enriched" "Detected in single" 27 "T-cells: 2.7" "Cancer enriched" "Detected in some" 5 "Leukemia: 5.4" NA NA "Cluster 27: T-cells - Unknown function" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 54: Immune cells - T cell receptor" "Cluster 59: Leukemia - T-cell receptor" "unprognostic (4.68e-1)" "unprognostic (4.55e-3)" "unprognostic (4.90e-1)" "unprognostic (6.17e-2)" "unprognostic (4.57e-1)" TRAJ20 ENSG00000211869 "T cell receptor alpha joining 20" 14 22524325-22524381 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "epididymis: 8.2;intestine: 4.2;lymphoid tissue: 16.1;retina: 10.5" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Skin Cutaneous Melanoma (TCGA): 2.0;Testicular Germ Cell Tumor (TCGA): 1.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 25 "MAIT T-cell: 191.5;memory CD4 T-cell: 124.9;memory CD8 T-cell: 194.5;naive CD4 T-cell: 138.8;naive CD8 T-cell: 140.6;T-reg: 225.5" "Lineage enriched" "Detected in single" 278 "T-cells: 225.5" "Not detected" "Not detected" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 54: Immune cells - T cell receptor" "Cluster 59: Leukemia - T-cell receptor" "unprognostic (2.45e-2)" "unprognostic (9.19e-2)" "unprognostic (2.56e-1)" "unprognostic (4.22e-2)" TRAJ21 ENSG00000211868 "T cell receptor alpha joining 21" 14 22523600-22523654 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "intestine: 6.5;lymphoid tissue: 10.2;retina: 11.3" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Testicular Germ Cell Tumor (TCGA): 3.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 109.0" "Lineage enriched" "Detected in many" 71 "T-cells: 109.0" "Not detected" "Not detected" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 8: Immune cells - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (1.65e-1)" "unprognostic (2.35e-1)" "unprognostic (2.66e-2)" "unprognostic (1.37e-1)" TRAJ22 ENSG00000211867 "T cell receptor alpha joining 22" 14 22522040-22522102 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 9 "epididymis: 3.8;lymphoid tissue: 10.2;retina: 12.0;stomach 1: 6.2" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 3.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory CD4 T-cell: 150.2;T-reg: 192.6" "Lineage enriched" "Detected in many" 87 "T-cells: 192.6" "Cancer enriched" "Detected in single" 9 "lymphoma: 5.9" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 54: Immune cells - T cell receptor" "Cluster 59: Leukemia - T-cell receptor" "unprognostic (5.18e-2)" "unprognostic (1.94e-1)" "unprognostic (1.64e-2)" TRAJ23 ENSG00000211866 "T cell receptor alpha joining 23" 14 22520416-22520478 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "lymphoid tissue: 7.2;retina: 12.0" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 1.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 182.1" "Lineage enriched" "Detected in many" 64 "T-cells: 182.1" "Cancer enhanced" "Detected in some" "thyroid cancer: 2.9" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 54: Immune cells - T cell receptor" "Cluster 59: Leukemia - T-cell receptor" "unprognostic (1.97e-1)" "unprognostic (1.35e-1)" "unprognostic (5.28e-1)" "unprognostic (1.59e-1)" "unprognostic (3.89e-1)" TRAJ24 ENSG00000211865 "T cell receptor alpha joining 24" 14 22519969-22520031 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 5.1;retina: 7.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 138 "MAIT T-cell: 28.5;memory CD4 T-cell: 52.1;memory CD8 T-cell: 65.0;naive CD4 T-cell: 49.4;naive CD8 T-cell: 60.6;T-reg: 95.7" "Lineage enriched" "Detected in single" 287 "T-cells: 95.7" "Not detected" "Not detected" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 54: Immune cells - T cell receptor" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (1.59e-1)" "unprognostic (1.47e-1)" "unprognostic (6.35e-2)" TRAJ25 ENSG00000211864 "T cell receptor alpha joining 25 (non-functional)" 14 22518812-22518871 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "lymphoid tissue: 4.0;retina: 5.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "MAIT T-cell: 4.6;memory CD4 T-cell: 5.0;memory CD8 T-cell: 5.5;naive CD4 T-cell: 6.1;naive CD8 T-cell: 2.0;T-reg: 7.6" "Lineage enriched" "Detected in single" 17 "T-cells: 7.6" "Not detected" "Not detected" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 54: Immune cells - T cell receptor" "Cluster 35: RS4;11 - Unknown function" "unprognostic (9.42e-2)" "unprognostic (1.32e-1)" "unprognostic (1.11e-1)" TRAJ26 ENSG00000211863 "T cell receptor alpha joining 26" 14 22518446-22518505 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "cervix: 4.0;lymphoid tissue: 3.4;retina: 10.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory CD4 T-cell: 80.6;memory CD8 T-cell: 77.5;naive CD4 T-cell: 88.3;naive CD8 T-cell: 95.1;T-reg: 152.1" "Lineage enriched" "Detected in many" 89 "T-cells: 152.1" "Not detected" "Not detected" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 54: Immune cells - T cell receptor" "Cluster 59: Leukemia - T-cell receptor" "unprognostic (2.96e-2)" "unprognostic (5.25e-2)" "unprognostic (7.44e-2)" TRAJ27 ENSG00000211862 "T cell receptor alpha joining 27" 14 22516273-22516331 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "intestine: 8.0;lymphoid tissue: 11.3;retina: 13.8;testis: 16.5" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Kidney Chromophobe (TCGA): 5.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "MAIT T-cell: 213.3;memory CD4 T-cell: 142.3;memory CD8 T-cell: 106.1;naive CD4 T-cell: 107.9;naive CD8 T-cell: 88.1;T-reg: 157.5" "Lineage enriched" "Detected in many" 50 "T-cells: 213.3" "Cancer enhanced" "Detected in some" "Leukemia: 1.2;lymphoma: 1.3" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 54: Immune cells - T cell receptor" "Cluster 59: Leukemia - T-cell receptor" "unprognostic (2.20e-2)" "unprognostic (3.21e-1)" "unprognostic (1.18e-1)" "unprognostic (3.07e-1)" "unprognostic (3.04e-1)" "unprognostic (1.68e-1)" TRAJ28 ENSG00000211861 "T cell receptor alpha joining 28" 14 22515623-22515688 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 10.3;retina: 13.7;stomach 1: 5.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 138.8" "Lineage enriched" "Detected in many" 20 "T-cells: 138.8" "Not detected" "Not detected" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 54: Immune cells - T cell receptor" "Cluster 59: Leukemia - T-cell receptor" "unprognostic (1.33e-1)" "unprognostic (2.41e-1)" "unprognostic (2.43e-2)" TRAJ29 ENSG00000211860 "T cell receptor alpha joining 29" 14 22513939-22513998 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 3.6;retina: 10.9;stomach 1: 3.5;testis: 3.2" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Bladder Urothelial Carcinoma (TCGA): 1.5" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "memory CD4 T-cell: 107.1;memory CD8 T-cell: 130.7;naive CD4 T-cell: 99.5;naive CD8 T-cell: 79.0;T-reg: 187.5" "Lineage enriched" "Detected in many" 61 "T-cells: 187.5" "Not detected" "Not detected" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 54: Immune cells - T cell receptor" "Cluster 35: RS4;11 - Unknown function" "unprognostic (2.19e-1)" "unprognostic (3.45e-1)" "unprognostic (3.89e-1)" TRAJ3 ENSG00000211886 "T cell receptor alpha joining 3" A0A075B6Y3 14 22543179-22543240 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in many" 5 "retina: 83.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 18 "MAIT T-cell: 139.6;memory CD4 T-cell: 200.9;memory CD8 T-cell: 172.5;naive CD4 T-cell: 186.8;naive CD8 T-cell: 294.6;T-reg: 199.4" "Lineage enriched" "Detected in many" 146 "T-cells: 294.6" "Cancer enriched" "Detected in some" 7 "Leukemia: 16.5" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 54: Immune cells - T cell receptor" "Cluster 59: Leukemia - T-cell receptor" "unprognostic (1.14e-1)" "unprognostic (2.83e-1)" "unprognostic (2.75e-1)" "unprognostic (1.18e-1)" "unprognostic (1.38e-1)" "unprognostic (8.33e-3)" "unprognostic (2.26e-1)" TRAJ30 ENSG00000211859 "T cell receptor alpha joining 30" 14 22512852-22512908 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 8.2;retina: 10.3;testis: 3.2" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Skin Cutaneous Melanoma (TCGA): 1.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "memory CD4 T-cell: 79.8;memory CD8 T-cell: 130.1;naive CD4 T-cell: 122.0;naive CD8 T-cell: 115.3;T-reg: 136.3" "Lineage enriched" "Detected in many" 72 "T-cells: 136.3" "Not detected" "Not detected" NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 54: Immune cells - T cell receptor" "Cluster 59: Leukemia - T-cell receptor" "unprognostic (1.43e-1)" "unprognostic (1.32e-1)" "unprognostic (2.70e-2)" TRAJ31 ENSG00000211858 "T cell receptor alpha joining 31" A0A075B700 14 22510968-22511024 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "lymphoid tissue: 14.7;retina: 16.3" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 1.0;Stomach Adenocarcinoma (TCGA): 3.7;Testicular Germ Cell Tumor (TCGA): 2.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "memory CD4 T-cell: 147.5;memory CD8 T-cell: 74.2;naive CD4 T-cell: 121.7;naive CD8 T-cell: 84.5;T-reg: 170.3" "Lineage enriched" "Detected in many" 102 "T-cells: 170.3" "Not detected" "Not detected" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 54: Immune cells - T cell receptor" "Cluster 35: RS4;11 - Unknown function" "unprognostic (9.98e-2)" "unprognostic (3.28e-1)" "unprognostic (5.14e-1)" "unprognostic (3.28e-1)" "unprognostic (2.78e-1)" "unprognostic (1.01e-1)" TRAJ32 ENSG00000211857 "T cell receptor alpha joining 32" 14 22509341-22509406 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 14.7;retina: 11.8" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Breast Invasive Carcinoma (TCGA): 3.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "MAIT T-cell: 354.5;memory CD4 T-cell: 153.0;memory CD8 T-cell: 130.9;naive CD4 T-cell: 177.3;naive CD8 T-cell: 133.4;T-reg: 188.3" "Lineage enriched" "Detected in many" 67 "T-cells: 354.5" "Cancer enhanced" "Detected in some" "Leukemia: 4.6;lymphoma: 9.3" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 54: Immune cells - T cell receptor" "Cluster 59: Leukemia - T-cell receptor" "unprognostic (6.56e-2)" "unprognostic (1.04e-1)" "unprognostic (4.78e-2)" "unprognostic (1.10e-1)" "unprognostic (1.57e-1)" "unprognostic (4.36e-1)" "unprognostic (1.76e-1)" TRAJ33 ENSG00000211856 "T cell receptor alpha joining 33" 14 22508602-22508658 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "intestine: 8.4;lymphoid tissue: 14.6;retina: 17.6" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Skin Cutaneous Melanoma (TCGA): 2.1;Stomach Adenocarcinoma (TCGA): 1.2;Testicular Germ Cell Tumor (TCGA): 2.0" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 5 "MAIT T-cell: 2143.5" "Lineage enriched" "Detected in all" 464 "T-cells: 2143.5" "Group enriched" "Detected in some" 6 "Leukemia: 1.3;lymphoma: 4.0" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 54: Immune cells - T cell receptor" "Cluster 46: Lymphoma - Humoral immune response" "unprognostic (6.09e-2)" "unprognostic (3.05e-1)" "unprognostic (7.96e-1)" "unprognostic (4.81e-2)" "unprognostic (3.14e-1)" TRAJ34 ENSG00000211855 "T cell receptor alpha joining 34" 14 22507666-22507723 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "intestine: 4.8;lymphoid tissue: 7.5;retina: 16.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "memory CD4 T-cell: 134.9;memory CD8 T-cell: 94.9;naive CD4 T-cell: 119.1;naive CD8 T-cell: 93.5;T-reg: 203.3" "Lineage enriched" "Detected in many" 181 "T-cells: 203.3" "Cancer enhanced" "Detected in single" "lymphoma: 1.9" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 54: Immune cells - T cell receptor" "Cluster 59: Leukemia - T-cell receptor" "unprognostic (1.76e-1)" "unprognostic (9.53e-2)" "unprognostic (6.19e-1)" "unprognostic (3.08e-2)" TRAJ35 ENSG00000211854 "T cell receptor alpha joining 35 (non-functional)" 14 22506644-22506702 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 4 "lymphoid tissue: 7.0;retina: 13.3" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Stomach Adenocarcinoma (TCGA): 1.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 17 "gdT-cell: 39.9;MAIT T-cell: 28.7;memory CD4 T-cell: 56.8;memory CD8 T-cell: 41.9;naive CD4 T-cell: 71.3;naive CD8 T-cell: 47.5;T-reg: 73.6" "Lineage enriched" "Detected in many" 24 "T-cells: 73.6" "Cancer enhanced" "Detected in some" "lymphoma: 1.8;Myeloma: 2.3;Rhabdoid: 4.4" NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 25: Non-specific - Transcription" "Cluster 65: Non-specific - Unknown function" "unprognostic (6.26e-3)" "unprognostic (1.94e-1)" "unprognostic (1.35e-1)" "unprognostic (2.48e-1)" TRAJ36 ENSG00000276699 "T cell receptor alpha joining 36" 14 22505110-22505167 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "retina: 24.8" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 1.0;Stomach Adenocarcinoma (TCGA): 1.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 24 "memory CD4 T-cell: 61.4;memory CD8 T-cell: 53.7;naive CD4 T-cell: 64.3;naive CD8 T-cell: 46.4;T-reg: 117.2" "Lineage enriched" "Detected in single" 135 "T-cells: 117.2" "Not detected" "Not detected" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 54: Immune cells - T cell receptor" "Cluster 59: Leukemia - T-cell receptor" "unprognostic (2.91e-1)" "unprognostic (8.12e-1)" "unprognostic (1.40e-2)" "unprognostic (4.81e-1)" TRAJ37 ENSG00000278661 "T cell receptor alpha joining 37" 14 22503750-22503814 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 21.5;retina: 25.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "memory CD4 T-cell: 202.5;memory CD8 T-cell: 72.7;naive CD4 T-cell: 141.0;naive CD8 T-cell: 79.7;T-reg: 184.4" "Lineage enriched" "Detected in many" 89 "T-cells: 202.5" "Not detected" "Not detected" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 54: Immune cells - T cell receptor" "Cluster 59: Leukemia - T-cell receptor" "unprognostic (1.50e-1)" "unprognostic (2.18e-1)" "unprognostic (5.89e-1)" "unprognostic (1.34e-2)" "unprognostic (1.67e-1)" TRAJ38 ENSG00000211851 "T cell receptor alpha joining 38" 14 22502231-22502292 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "epididymis: 11.7;lymphoid tissue: 9.2;retina: 21.2" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Bladder Urothelial Carcinoma (TCGA): 1.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 124.5" "Lineage enriched" "Detected in many" 24 "T-cells: 124.5" "Cancer enriched" "Detected in single" 5 "Rhabdoid: 3.2" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 54: Immune cells - T cell receptor" "Cluster 5: Rhabdoid - Unknown function" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (3.08e-2)" "unprognostic (1.68e-1)" "unprognostic (9.65e-2)" "unprognostic (1.56e-2)" "unprognostic (6.44e-2)" TRAJ39 ENSG00000211850 "T cell receptor alpha joining 39" 14 22501601-22501663 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "epididymis: 23.0;heart muscle: 14.5;lymphoid tissue: 17.8;retina: 24.7" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney Chromophobe (TCGA): 4.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory CD4 T-cell: 205.4;T-reg: 158.4" "Lineage enriched" "Detected in many" 58 "T-cells: 205.4" "Cancer enriched" "Detected in single" 9 "Rhabdoid: 5.0" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 40: Non-specific - Mixed function" "Cluster 54: Immune cells - T cell receptor" "Cluster 5: Rhabdoid - Unknown function" "unprognostic (1.32e-2)" "unprognostic (6.05e-2)" "unprognostic (2.25e-1)" "unprognostic (3.13e-1)" "unprognostic (8.64e-2)" "unprognostic (7.23e-2)" "unprognostic (3.89e-2)" TRAJ4 ENSG00000211885 "T cell receptor alpha joining 4" 14 22542199-22542261 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 6 "lymphoid tissue: 17.0;retina: 52.2" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Skin Cutaneous Melanoma (TCGA): 3.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 36 "MAIT T-cell: 78.8;memory CD4 T-cell: 223.4;memory CD8 T-cell: 165.0;naive CD4 T-cell: 175.8;naive CD8 T-cell: 107.4;T-reg: 273.9" "Lineage enriched" "Detected in many" 91 "T-cells: 273.9" "Cancer enhanced" "Detected in some" "Leukemia: 2.5;lymphoma: 1.5" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 54: Immune cells - T cell receptor" "Cluster 59: Leukemia - T-cell receptor" "unprognostic (9.08e-2)" "unprognostic (1.44e-1)" "unprognostic (3.64e-1)" "unprognostic (6.46e-1)" "unprognostic (1.07e-2)" "unprognostic (4.18e-1)" TRAJ40 ENSG00000211849 "T cell receptor alpha joining 40" 14 22499689-22499749 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 11 "lymphoid tissue: 5.2;retina: 18.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "memory CD4 T-cell: 132.1;memory CD8 T-cell: 93.4;naive CD4 T-cell: 137.5;naive CD8 T-cell: 86.5;T-reg: 244.9" "Lineage enriched" "Detected in many" 25 "T-cells: 244.9" "Not detected" "Not detected" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 25: Non-specific - Transcription" "Cluster 59: Leukemia - T-cell receptor" "unprognostic (2.57e-1)" "unprognostic (5.43e-2)" "unprognostic (2.26e-1)" TRAJ41 ENSG00000211848 "T cell receptor alpha joining 41" 14 22497657-22497718 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 3.2;retina: 10.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "memory CD4 T-cell: 95.3;memory CD8 T-cell: 78.0;naive CD4 T-cell: 96.4;naive CD8 T-cell: 305.5;T-reg: 90.6" "Lineage enriched" "Detected in many" 139 "T-cells: 305.5" "Not detected" "Not detected" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 25: Non-specific - Transcription" "Cluster 65: Non-specific - Unknown function" "unprognostic (3.92e-2)" "unprognostic (2.72e-2)" TRAJ42 ENSG00000211847 "T cell receptor alpha joining 42" A0A075B6Y9 14 22496887-22496952 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 4 "lymphoid tissue: 12.2;retina: 21.3" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Skin Cutaneous Melanoma (TCGA): 3.3;Stomach Adenocarcinoma (TCGA): 1.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory CD4 T-cell: 152.3;memory CD8 T-cell: 100.6;naive CD4 T-cell: 129.9;naive CD8 T-cell: 91.3;T-reg: 204.1" "Lineage enriched" "Detected in many" 73 "T-cells: 204.1" "Cancer enhanced" "Detected in single" "lymphoma: 2.0" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 25: Non-specific - Transcription" "Cluster 21: Lymphoma - Adaptive immune response" "unprognostic (3.30e-1)" "unprognostic (1.39e-1)" "unprognostic (1.37e-2)" "unprognostic (2.16e-1)" "unprognostic (1.86e-2)" "unprognostic (2.61e-1)" TRAJ43 ENSG00000211846 "T cell receptor alpha joining 43" 14 22495913-22495966 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 5.4;retina: 12.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 10 "gdT-cell: 162.9;memory CD4 T-cell: 178.9;memory CD8 T-cell: 247.5;naive CD4 T-cell: 196.4;naive CD8 T-cell: 235.0;T-reg: 264.5" "Lineage enriched" "Detected in all" 30 "T-cells: 264.5" "Not detected" "Not detected" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 25: Non-specific - Transcription" "Cluster 65: Non-specific - Unknown function" "unprognostic (1.63e-1)" "unprognostic (4.70e-1)" TRAJ44 ENSG00000211845 "T cell receptor alpha joining 44" 14 22494821-22494883 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 6 "lymphoid tissue: 24.4;retina: 19.3" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney Chromophobe (TCGA): 1.8" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 18 "gdT-cell: 216.8;memory CD4 T-cell: 215.3;memory CD8 T-cell: 64.6;naive CD4 T-cell: 161.4;naive CD8 T-cell: 81.1;T-reg: 193.3" "Lineage enriched" "Detected in many" 25 "T-cells: 216.8" "Cancer enhanced" "Detected in some" "lymphoma: 3.2;Rhabdoid: 3.1" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 25: Non-specific - Transcription" "Cluster 21: Lymphoma - Adaptive immune response" "unprognostic (5.96e-2)" "unprognostic (3.73e-1)" "unprognostic (7.31e-1)" "unprognostic (5.34e-1)" "unprognostic (1.75e-1)" "unprognostic (2.53e-1)" TRAJ45 ENSG00000211844 "T cell receptor alpha joining 45" 14 22493925-22493990 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 12.9;retina: 19.9" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 2.1" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "gdT-cell: 320.1;memory CD4 T-cell: 131.1;memory CD8 T-cell: 151.6;naive CD4 T-cell: 135.0;naive CD8 T-cell: 139.0;T-reg: 207.5" "Lineage enriched" "Detected in many" 7 "T-cells: 320.1" "Cancer enriched" "Detected in some" 4 "lymphoma: 9.8" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 25: Non-specific - Transcription" "Cluster 21: Lymphoma - Adaptive immune response" "unprognostic (9.77e-2)" "unprognostic (2.37e-1)" "unprognostic (2.29e-1)" "unprognostic (3.41e-1)" "unprognostic (3.72e-1)" "unprognostic (2.67e-2)" TRAJ46 ENSG00000211843 "T cell receptor alpha joining 46" 14 22493403-22493465 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 7 "retina: 12.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "gdT-cell: 86.7" "Lineage enriched" "Detected in many" 9 "T-cells: 86.7" "Not detected" "Not detected" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 42: Retina - Visual perception" "Cluster 25: Non-specific - Transcription" "Cluster 55: Lymphoma - Immune response" "unprognostic (4.62e-3)" "unprognostic (1.07e-2)" "unprognostic (1.52e-1)" TRAJ47 ENSG00000211842 "T cell receptor alpha joining 47" 14 22492851-22492907 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 5.8;retina: 12.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 13 "gdT-cell: 40.4;memory CD4 T-cell: 106.5;memory CD8 T-cell: 87.4;naive CD4 T-cell: 76.6;naive CD8 T-cell: 50.7;T-reg: 133.4" "Lineage enriched" "Detected in many" 21 "T-cells: 133.4" "Group enriched" "Detected in some" 5 "lymphoma: 1.1;Myeloma: 1.1" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 25: Non-specific - Transcription" "Cluster 20: Myeloma - Immune response" "unprognostic (4.77e-1)" "unprognostic (3.71e-1)" TRAJ48 ENSG00000211841 "T cell receptor alpha joining 48" 14 22490491-22490553 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 7.3;retina: 25.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "memory B-cell: 37.8;memory CD4 T-cell: 80.9;memory CD8 T-cell: 71.4;naive CD4 T-cell: 100.3;naive CD8 T-cell: 78.4;T-reg: 149.7" "Group enriched" "Detected in many" 14 "B-cells: 37.8;T-cells: 149.7" "Cancer enhanced" "Detected in single" "lymphoma: 2.0" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 25: Non-specific - Transcription" "Cluster 65: Non-specific - Unknown function" "unprognostic (2.10e-1)" "unprognostic (2.97e-1)" "unprognostic (8.47e-1)" "unprognostic (1.30e-1)" TRAJ49 ENSG00000211840 "T cell receptor alpha joining 49" 14 22489488-22489543 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 39 "retina: 380.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 9 "gdT-cell: 258.3;memory CD4 T-cell: 196.6;memory CD8 T-cell: 121.5;naive CD4 T-cell: 200.8;naive CD8 T-cell: 146.8;NK-cell: 104.5;T-reg: 362.0" "Group enriched" "Detected in all" 10 "NK-cells: 104.5;T-cells: 362.0" "Group enriched" "Detected in some" 5 "head and neck cancer: 6.5;Leukemia: 3.0;lymphoma: 5.7;Rhabdoid: 9.3;Sarcoma: 3.8" NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 42: Retina - Visual perception" "Cluster 25: Non-specific - Transcription" "Cluster 65: Non-specific - Unknown function" "unprognostic (1.79e-1)" "unprognostic (4.43e-2)" "unprognostic (1.03e-2)" "unprognostic (3.39e-1)" TRAJ5 ENSG00000211884 "T cell receptor alpha joining 5" 14 22540247-22540306 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "intestine: 9.3;lymphoid tissue: 11.4;retina: 41.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 62 "MAIT T-cell: 63.3;memory CD4 T-cell: 157.0;memory CD8 T-cell: 125.1;naive CD4 T-cell: 110.6;naive CD8 T-cell: 113.5;T-reg: 245.3" "Lineage enriched" "Detected in many" 112 "T-cells: 245.3" "Group enriched" "Detected in some" 5 "Leukemia: 4.3;lymphoma: 1.3" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 54: Immune cells - T cell receptor" "Cluster 59: Leukemia - T-cell receptor" "unprognostic (3.39e-1)" "unprognostic (1.40e-2)" "unprognostic (5.61e-2)" "unprognostic (8.39e-2)" "unprognostic (8.57e-2)" "unprognostic (2.64e-3)" TRAJ50 ENSG00000211839 "T cell receptor alpha joining 50" 14 22488593-22488652 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 5 "lymphoid tissue: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "T-reg: 72.6" "Lineage enriched" "Detected in many" 22 "T-cells: 72.6" "Not detected" "Not detected" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 54: Immune cells - T cell receptor" "Cluster 35: RS4;11 - Unknown function" "unprognostic (6.00e-1)" "unprognostic (2.46e-1)" "unprognostic (1.19e-2)" TRAJ52 ENSG00000211838 "T cell receptor alpha joining 52" 14 22486228-22486296 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "bone marrow: 2.4;lymphoid tissue: 8.6;stomach 1: 4.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 128.3;T-reg: 167.6" "Lineage enriched" "Detected in many" 155 "T-cells: 167.6" "Not detected" "Not detected" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 35: Non-specific - DNA binding" "Cluster 65: Non-specific - Unknown function" "unprognostic (8.95e-2)" "unprognostic (5.24e-1)" TRAJ53 ENSG00000211837 "T cell receptor alpha joining 53" 14 22483004-22483069 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 2.9;lymphoid tissue: 10.3;stomach 1: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Skin Cutaneous Melanoma (TCGA): 1.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 17 "memory CD4 T-cell: 79.1;memory CD8 T-cell: 38.7;naive CD4 T-cell: 94.3;naive CD8 T-cell: 39.0;T-reg: 147.4" "Lineage enriched" "Detected in many" 48 "T-cells: 147.4" "Not detected" "Not detected" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 65: Non-specific - Unknown function" "unprognostic (1.22e-1)" "unprognostic (2.28e-1)" TRAJ54 ENSG00000211836 "T cell receptor alpha joining 54" 14 22482287-22482346 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "bone marrow: 2.8;intestine: 4.0;lymphoid tissue: 8.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebellum: 6.9" "Group enriched" "Detected in many" 5 "memory CD4 T-cell: 163.1;memory CD8 T-cell: 115.3;naive CD4 T-cell: 186.7;naive CD8 T-cell: 82.5;T-reg: 173.3" "Lineage enriched" "Detected in many" 7 "T-cells: 186.7" "Cancer enhanced" "Detected in single" "lymphoma: 1.1" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 35: Non-specific - DNA binding" "Cluster 65: Non-specific - Unknown function" "Cluster 87: B-cells - Adaptive immunity: Humoral response" "unprognostic (1.70e-1)" "unprognostic (3.19e-1)" "unprognostic (3.55e-2)" TRAJ56 ENSG00000211835 "T cell receptor alpha joining 56" 14 22479521-22479582 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "intestine: 3.0;lymphoid tissue: 4.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebellum: 10.8" "Group enriched" "Detected in many" 40 "memory CD4 T-cell: 49.9;memory CD8 T-cell: 52.1;naive CD4 T-cell: 47.3;naive CD8 T-cell: 20.5;T-reg: 49.2" "Lineage enriched" "Detected in single" 58 "T-cells: 52.1" "Not detected" "Not detected" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 35: Non-specific - DNA binding" "Cluster 65: Non-specific - Unknown function" "unprognostic (4.87e-1)" "unprognostic (2.94e-1)" "unprognostic (3.94e-1)" TRAJ57 ENSG00000211834 "T cell receptor alpha joining 57" 14 22478872-22478934 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "intestine: 5.1;lymphoid tissue: 9.8;salivary gland: 7.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebellum: 8.1" "Group enriched" "Detected in many" 26 "memory CD4 T-cell: 81.2;memory CD8 T-cell: 75.0;naive CD4 T-cell: 92.3;naive CD8 T-cell: 45.0;T-reg: 156.2" "Lineage enriched" "Detected in many" 45 "T-cells: 156.2" "Cancer enhanced" "Detected in single" "lymphoma: 1.4" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 2: Neurons - Nucleosome" "Cluster 46: Lymphoma - Humoral immune response" "unprognostic (1.58e-1)" "unprognostic (8.55e-2)" TRAJ58 ENSG00000211833 "T cell receptor alpha joining 58 (non-functional)" 14 22477707-22477769 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 7.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebellum: 9.4" "Group enriched" "Detected in many" 14 "memory CD4 T-cell: 58.4;memory CD8 T-cell: 41.0;naive CD4 T-cell: 63.7;naive CD8 T-cell: 20.7;T-reg: 57.5" "Lineage enriched" "Detected in many" 41 "T-cells: 63.7" "Cancer enhanced" "Detected in single" "lymphoma: 1.0" NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 35: Non-specific - DNA binding" "Cluster 65: Non-specific - Unknown function" "unprognostic (2.22e-1)" TRAJ59 ENSG00000211832 "T cell receptor alpha joining 59 (non-functional)" 14 22476553-22476606 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "gallbladder: 1.5;lymphoid tissue: 3.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in many" 5 "cerebellum: 8.3" "Immune cell enhanced" "Detected in some" "gdT-cell: 3.9;naive CD8 T-cell: 5.3" "Lineage enriched" "Detected in single" 7 "T-cells: 5.3" "Not detected" "Not detected" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 35: Non-specific - DNA binding" "Cluster 65: Non-specific - Unknown function" TRAJ6 ENSG00000211883 "T cell receptor alpha joining 6" 14 22539073-22539134 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "lymphoid tissue: 14.6;retina: 52.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 28 "MAIT T-cell: 137.7;memory CD4 T-cell: 135.4;memory CD8 T-cell: 143.2;naive CD4 T-cell: 138.4;naive CD8 T-cell: 76.5;T-reg: 265.1" "Lineage enriched" "Detected in many" 192 "T-cells: 265.1" "Group enriched" "Detected in some" 7 "Leukemia: 2.6;lymphoma: 1.8;Rhabdoid: 1.1" NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 54: Immune cells - T cell receptor" "Cluster 59: Leukemia - T-cell receptor" "unprognostic (1.61e-1)" "unprognostic (3.45e-1)" "unprognostic (5.91e-3)" "unprognostic (1.46e-1)" "unprognostic (4.10e-2)" "potential prognostic favorable (3.76e-6)" "unprognostic (4.55e-1)" TRAJ61 ENSG00000211831 "T cell receptor alpha joining 61 (non-functional)" 14 22475316-22475375 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 71 "lymphoid tissue: 7.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebellum: 7.5" "Group enriched" "Detected in many" 8 "gdT-cell: 4.2;memory CD4 T-cell: 4.8;memory CD8 T-cell: 4.8;naive CD4 T-cell: 8.0;naive CD8 T-cell: 4.1;NK-cell: 4.3;T-reg: 7.6" "Group enriched" "Detected in many" 9 "NK-cells: 4.3;T-cells: 8.0" "Not detected" "Not detected" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 80: Thymus - Adaptive immune response" "Cluster 35: Non-specific - DNA binding" "Cluster 65: Non-specific - Unknown function" TRAJ7 ENSG00000211882 "T cell receptor alpha joining 7" 14 22537622-22537680 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 7 "lymphoid tissue: 14.7;retina: 39.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 48 "MAIT T-cell: 27.0;memory CD4 T-cell: 44.3;memory CD8 T-cell: 28.7;naive CD4 T-cell: 54.9;naive CD8 T-cell: 31.2;T-reg: 87.6" "Lineage enriched" "Detected in single" 92 "T-cells: 87.6" "Cancer enhanced" "Detected in some" "Leukemia: 1.7;lymphoma: 1.6;Rhabdoid: 1.2" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 54: Immune cells - T cell receptor" "Cluster 59: Leukemia - T-cell receptor" "unprognostic (3.71e-2)" "unprognostic (1.37e-1)" "unprognostic (5.60e-1)" "unprognostic (6.63e-1)" "unprognostic (4.82e-2)" TRAJ9 ENSG00000211880 "T cell receptor alpha joining 9" 14 22535554-22535614 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 21.2;retina: 28.1" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Stomach Adenocarcinoma (TCGA): 1.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "memory CD4 T-cell: 137.7;memory CD8 T-cell: 150.7;naive CD4 T-cell: 118.9;naive CD8 T-cell: 188.3;T-reg: 298.3" "Lineage enriched" "Detected in many" 58 "T-cells: 298.3" "Cancer enhanced" "Detected in some" "Leukemia: 3.0;lymphoma: 1.7" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 54: Immune cells - T cell receptor" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (2.87e-1)" "unprognostic (3.45e-1)" "unprognostic (2.21e-1)" "unprognostic (1.31e-1)" "unprognostic (1.82e-3)" "unprognostic (6.64e-2)" TRAK1 "KIAA1042, MILT1, OIP106" ENSG00000182606 "Trafficking kinesin protein 1" Q9UPV9 3 42013802-42225890 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 158.2;skeletal muscle: 245.8;tongue: 189.2" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005853, HPA011367" Approved Approved "Nucleoplasm,Endoplasmic reticulum" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 29 "Endoplasmic reticulum" Nucleoplasm "HPA005853: , HPA011367: " "unprognostic (5.30e-3)" "unprognostic (8.00e-2)" "unprognostic (4.87e-2)" "unprognostic (2.07e-1)" "unprognostic (1.17e-1)" "unprognostic (1.09e-3)" "unprognostic (1.55e-1)" "unprognostic (2.90e-2)" "unprognostic (2.02e-1)" "potential prognostic unfavorable (4.57e-4)" "potential prognostic favorable (5.28e-4)" "unprognostic (1.22e-3)" "unprognostic (4.14e-3)" "unprognostic (5.22e-2)" "unprognostic (2.33e-1)" "unprognostic (2.47e-1)" "unprognostic (1.02e-1)" "unprognostic (1.80e-1)" "unprognostic (6.58e-3)" "unprognostic (6.51e-3)" "unprognostic (3.68e-1)" "unprognostic (3.52e-2)" "unprognostic (1.14e-1)" "unprognostic (3.20e-2)" "unprognostic (7.98e-3)" "unprognostic (1.97e-3)" "unprognostic (3.42e-2)" "unprognostic (7.64e-2)" "unprognostic (1.54e-1)" "unprognostic (1.28e-2)" "unprognostic (9.81e-2)" TRAK2 "ALS2CR3, CALS-C, GRIF-1, KIAA0549, MILT2, OIP98" ENSG00000115993 "Trafficking kinesin protein 2" O60296 2 201377207-201451500 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 195.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 306.7;Melanocytes: 230.0;Somatotrophs: 214.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015827, HPA062163" Uncertain Approved "Nucleoplasm,Nuclear bodies,Vesicles" NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 47: Leukemia - Hemostasis" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 25 "Nucleoplasm, Nuclear bodies" Vesicles "HPA015827: , HPA062163: " "unprognostic (6.89e-3)" "unprognostic (1.89e-1)" "unprognostic (8.90e-2)" "unprognostic (1.41e-1)" "unprognostic (2.22e-1)" "unprognostic (2.14e-1)" "unprognostic (2.42e-1)" "unprognostic (5.34e-2)" "unprognostic (1.03e-1)" "unprognostic (6.00e-2)" "validated prognostic favorable (1.55e-6)" "validated prognostic favorable (5.16e-4)" "unprognostic (1.39e-1)" "unprognostic (4.94e-2)" "unprognostic (2.96e-2)" "unprognostic (1.71e-2)" "unprognostic (3.23e-2)" "unprognostic (3.66e-2)" "unprognostic (1.21e-1)" "unprognostic (4.00e-2)" "unprognostic (1.44e-1)" "unprognostic (8.20e-2)" "unprognostic (3.50e-1)" "unprognostic (8.84e-2)" "unprognostic (1.33e-1)" "unprognostic (1.65e-1)" "unprognostic (1.15e-1)" "unprognostic (2.71e-1)" "unprognostic (4.11e-1)" "unprognostic (1.82e-2)" "unprognostic (1.15e-1)" TRAM1 "TRAM, TRAMP" ENSG00000067167 "Translocation associated membrane protein 1" Q15629 8 70573218-70608416 "Plasma proteins, Predicted membrane proteins, Transporters" "Host-virus interaction, Protein transport, Translocation, Transport, Unfolded protein response" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 1041.7;Plasma cells: 628.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023929 Approved NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 22: Epididymis - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 67: Plasma cells - Plasma cell differentiation" 10 "HPA023929: " "unprognostic (8.45e-2)" "unprognostic (4.76e-3)" "unprognostic (5.49e-2)" "potential prognostic unfavorable (7.32e-4)" "unprognostic (2.05e-1)" "unprognostic (5.63e-2)" "unprognostic (3.33e-2)" "unprognostic (5.73e-3)" "unprognostic (7.09e-2)" "unprognostic (1.33e-2)" "potential prognostic favorable (1.83e-4)" "unprognostic (1.70e-1)" "potential prognostic unfavorable (2.12e-8)" "unprognostic (4.91e-2)" "unprognostic (2.38e-1)" "unprognostic (9.84e-2)" "unprognostic (7.96e-2)" "unprognostic (1.15e-2)" "unprognostic (4.81e-2)" "unprognostic (3.72e-2)" "unprognostic (6.43e-3)" "unprognostic (1.39e-2)" "unprognostic (5.89e-2)" "unprognostic (8.33e-2)" "unprognostic (3.22e-1)" "unprognostic (1.33e-1)" "unprognostic (6.79e-2)" "unprognostic (1.09e-1)" "unprognostic (3.61e-1)" "unprognostic (2.23e-1)" "unprognostic (1.47e-1)" TRAM1L1 MGC26568 ENSG00000174599 "Translocation associated membrane protein 1 like 1" Q8N609 4 117083554-117085576 "Predicted membrane proteins, Transporters" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 7.1;Epididymal principal cells: 9.1;Oligodendrocyte progenitor cells: 11.2;Oligodendrocytes: 14.7;Other brain neurons: 7.6;Retinal pigment epithelial cells: 12.8;Undifferentiated spermatogonia: 7.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA044560 Uncertain Uncertain Mitochondria NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 80: Oligodendrocytes - Myelination" 20 Mitochondria "HPA044560: " "unprognostic (1.33e-1)" "unprognostic (3.03e-1)" "unprognostic (3.31e-2)" "unprognostic (1.43e-1)" "unprognostic (1.73e-2)" "unprognostic (2.51e-2)" "potential prognostic favorable (1.24e-5)" "unprognostic (1.78e-1)" "unprognostic (8.76e-2)" "unprognostic (2.35e-1)" "unprognostic (2.27e-1)" "unprognostic (6.18e-2)" "unprognostic (7.12e-3)" "unprognostic (2.28e-1)" "unprognostic (2.00e-1)" "unprognostic (2.97e-3)" "unprognostic (5.23e-1)" "unprognostic (1.89e-1)" "unprognostic (2.01e-2)" "unprognostic (1.57e-1)" "unprognostic (3.57e-2)" "unprognostic (6.95e-2)" TRAM2 KIAA0057 ENSG00000065308 "Translocation associated membrane protein 2" Q15035 6 52497408-52577060 "Predicted membrane proteins, Transporters" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 88.9;Late spermatids: 199.4;Plasma cells: 142.8;Podocytes: 210.1" "Cell type enhanced" "Detected in many" "endothelial cell: 76.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA035092, HPA057925" Approved Approved Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 44: Plasma cells - Antibody production & secretion" 1 Cytosol "HPA035092: , HPA057925: " "unprognostic (2.23e-1)" "unprognostic (1.97e-2)" "potential prognostic favorable (1.05e-4)" "unprognostic (6.82e-2)" "unprognostic (2.29e-1)" "unprognostic (4.56e-3)" "unprognostic (2.33e-1)" "unprognostic (6.22e-2)" "unprognostic (1.01e-1)" "unprognostic (2.45e-2)" "unprognostic (1.23e-1)" "unprognostic (5.36e-3)" "potential prognostic unfavorable (1.34e-4)" "unprognostic (3.10e-2)" "unprognostic (3.54e-2)" "unprognostic (1.79e-2)" "unprognostic (4.44e-1)" "unprognostic (2.58e-1)" "unprognostic (9.60e-2)" "unprognostic (1.04e-1)" "potential prognostic unfavorable (3.01e-5)" "unprognostic (2.80e-1)" "unprognostic (2.89e-1)" "unprognostic (3.74e-1)" "unprognostic (9.01e-2)" "unprognostic (3.41e-1)" "unprognostic (5.95e-2)" "unprognostic (2.28e-2)" "unprognostic (1.46e-1)" "unprognostic (6.94e-2)" "unprognostic (3.21e-2)" TRANK1 "KIAA0342, LBA1" ENSG00000168016 "Tetratricopeptide repeat and ankyrin repeat containing 1" O15050 3 36826819-36945057 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 127.6;Goblet cells: 127.3;Granulosa cells: 135.4;Microglia: 130.4;Retinal ganglion cells: 127.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 116.0" "Lineage enriched" "Detected in all" 7 "granulocytes: 116.0" "Cancer enhanced" "Detected in many" "lymphoma: 22.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035508 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 61: Non-specific - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" Nucleoplasm Cytosol "HPA035508: " "unprognostic (1.71e-2)" "unprognostic (2.48e-2)" "unprognostic (1.46e-1)" "unprognostic (2.37e-2)" "unprognostic (2.42e-1)" "unprognostic (2.90e-1)" "unprognostic (2.09e-1)" "unprognostic (6.29e-3)" "unprognostic (2.08e-2)" "unprognostic (2.45e-1)" "potential prognostic favorable (1.43e-4)" "unprognostic (1.07e-2)" "unprognostic (1.43e-1)" "unprognostic (4.94e-1)" "unprognostic (5.05e-3)" "unprognostic (2.42e-1)" "unprognostic (9.00e-2)" "unprognostic (3.27e-2)" "unprognostic (1.56e-1)" "unprognostic (5.99e-2)" "unprognostic (9.91e-2)" "unprognostic (9.53e-2)" "unprognostic (6.29e-3)" "unprognostic (2.23e-1)" "unprognostic (1.09e-3)" "unprognostic (3.74e-2)" "unprognostic (1.77e-1)" "unprognostic (7.36e-2)" "unprognostic (1.18e-1)" "unprognostic (7.38e-2)" TRAP1 "HSP75, HSP90L" ENSG00000126602 "TNF receptor associated protein 1" Q12931 16 3651639-3717553 "Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 188.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041082, HPA044227" Enhanced Enhanced Mitochondria NA NA 5100000 "Cluster 33: Non-specific - ATP binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 1: Neurons - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 52 Mitochondria "HPA041082: , HPA044227: " "unprognostic (4.98e-2)" "unprognostic (4.03e-2)" "unprognostic (1.69e-1)" "unprognostic (2.26e-1)" "unprognostic (1.10e-2)" "unprognostic (1.48e-1)" "unprognostic (1.25e-1)" "unprognostic (1.15e-1)" "unprognostic (3.53e-3)" "unprognostic (2.84e-2)" "potential prognostic favorable (4.57e-5)" "unprognostic (1.70e-1)" "unprognostic (1.95e-2)" "unprognostic (1.86e-2)" "unprognostic (9.81e-3)" "unprognostic (2.00e-3)" "unprognostic (9.28e-3)" "unprognostic (2.96e-1)" "unprognostic (4.58e-2)" "unprognostic (1.55e-3)" "unprognostic (1.15e-1)" "unprognostic (1.20e-1)" "unprognostic (2.80e-1)" "unprognostic (2.23e-2)" "unprognostic (1.73e-3)" "unprognostic (2.89e-2)" "unprognostic (2.59e-1)" "unprognostic (5.95e-2)" "unprognostic (5.20e-1)" "unprognostic (1.17e-1)" "unprognostic (1.15e-2)" TRAPPC1 "BET5, MUM2" ENSG00000170043 "Trafficking protein particle complex subunit 1" Q9Y5R8 17 7930345-7932123 "Essential proteins, Predicted intracellular proteins" "ER-Golgi transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 321.2;Megakaryocytes: 302.9;Migrating cytotrophoblasts: 254.8;Platelets: 490.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052398 Approved NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 47: Platelets - Hemostasis" 62 "HPA052398: " "unprognostic (3.02e-3)" "unprognostic (1.17e-1)" "unprognostic (3.81e-3)" "unprognostic (1.38e-2)" "unprognostic (9.84e-2)" "unprognostic (1.07e-1)" "potential prognostic unfavorable (3.14e-5)" "unprognostic (4.37e-2)" "unprognostic (2.84e-3)" "unprognostic (6.80e-3)" "unprognostic (1.14e-2)" "unprognostic (2.32e-1)" "unprognostic (8.19e-3)" "unprognostic (6.42e-2)" "unprognostic (4.13e-2)" "unprognostic (1.29e-1)" "unprognostic (2.85e-1)" "unprognostic (2.87e-2)" "unprognostic (7.88e-2)" "unprognostic (2.43e-2)" "unprognostic (5.32e-2)" "unprognostic (2.95e-2)" "unprognostic (9.01e-2)" "unprognostic (5.47e-2)" "unprognostic (2.85e-3)" "unprognostic (1.39e-1)" "unprognostic (2.39e-1)" "unprognostic (2.25e-2)" "unprognostic (2.00e-1)" "unprognostic (3.27e-1)" "unprognostic (1.31e-1)" TRAPPC10 "EHOC-1, TMEM1, TRS130" ENSG00000160218 "Trafficking protein particle complex subunit 10" P48553 21 44012309-44106552 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Transport" "Autism spectrum disorder, Disease variant, Dwarfism, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Podocytes: 256.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 9.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050423 Supported NA NA "Cluster 24: Non-specific - Transcription" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 29 "HPA050423: " "unprognostic (2.73e-2)" "unprognostic (1.53e-2)" "unprognostic (3.08e-1)" "unprognostic (1.55e-1)" "unprognostic (1.23e-1)" "unprognostic (1.92e-1)" "unprognostic (4.89e-1)" "unprognostic (9.25e-2)" "unprognostic (1.21e-1)" "unprognostic (6.10e-2)" "unprognostic (3.53e-3)" "unprognostic (7.98e-2)" "unprognostic (1.56e-2)" "unprognostic (9.33e-3)" "unprognostic (8.45e-3)" "unprognostic (1.54e-2)" "unprognostic (1.36e-1)" "unprognostic (5.69e-2)" "unprognostic (4.07e-1)" "unprognostic (4.35e-2)" "unprognostic (2.61e-3)" "unprognostic (1.52e-1)" "unprognostic (1.37e-1)" "unprognostic (1.33e-1)" "unprognostic (5.00e-2)" "unprognostic (1.43e-1)" "unprognostic (1.88e-2)" "unprognostic (2.16e-1)" "unprognostic (2.02e-1)" "unprognostic (5.34e-2)" "unprognostic (1.96e-1)" TRAPPC11 "C4orf41, FLJ12716, foigr, gry" ENSG00000168538 "Trafficking protein particle complex subunit 11" Q7Z392 4 183659267-183713594 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "ER-Golgi transport, Transport" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038173 Uncertain Vesicles,Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 31: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 7: Non-specific - Transcription" 42 Cytosol Vesicles "HPA038173: " "unprognostic (5.86e-2)" "unprognostic (1.04e-1)" "unprognostic (2.81e-2)" "unprognostic (2.76e-2)" "unprognostic (3.12e-1)" "unprognostic (2.43e-1)" "unprognostic (1.42e-1)" "unprognostic (2.69e-2)" "unprognostic (6.19e-2)" "potential prognostic favorable (9.71e-7)" "unprognostic (1.08e-3)" "unprognostic (8.07e-2)" "unprognostic (6.13e-2)" "unprognostic (1.34e-1)" "unprognostic (8.80e-3)" "unprognostic (4.79e-2)" "unprognostic (1.81e-1)" "unprognostic (3.46e-3)" "unprognostic (3.61e-2)" "unprognostic (4.72e-2)" "unprognostic (2.24e-2)" "unprognostic (3.21e-1)" "unprognostic (1.21e-1)" "unprognostic (1.17e-2)" "unprognostic (2.33e-1)" "unprognostic (4.73e-1)" "unprognostic (1.62e-1)" "unprognostic (5.48e-2)" "unprognostic (2.59e-1)" TRAPPC12 "CGI-87, TTC-15, TTC15" ENSG00000171853 "Trafficking protein particle complex subunit 12" Q8WVT3 2 3379675-3485094 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Transport" "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 94.2" "Cell type enhanced" "Detected in many" "Astrocytes: 100.3;Bergmann glia: 104.9;Brain inhibitory neurons: 91.1;Choroid plexus epithelial cells: 108.7;Distal convoluted tubule cells: 91.2;Early spermatids: 158.1;Late primary spermatocytes: 161.6;Late spermatids: 351.2;Microglia: 110.1;Oligodendrocyte progenitor cells: 106.3;Oligodendrocytes: 97.6;Proximal tubule cells: 96.3;Renal collecting duct intercalated cells: 121.5;Renal connecting tubule cells: 110.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034799, HPA043196" Uncertain Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 67: Testis - Mixed function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 102: Non-specific - Mixed function" 23 "Nucleoplasm, Golgi apparatus" "HPA034799: , HPA043196: " "unprognostic (2.51e-1)" "unprognostic (2.86e-2)" "unprognostic (1.73e-1)" "unprognostic (5.44e-2)" "unprognostic (2.45e-1)" "unprognostic (2.05e-1)" "unprognostic (3.20e-3)" "unprognostic (1.57e-1)" "unprognostic (2.29e-1)" "unprognostic (1.99e-1)" "unprognostic (2.78e-1)" "unprognostic (5.02e-3)" "unprognostic (1.91e-1)" "unprognostic (8.84e-2)" "unprognostic (1.56e-1)" "unprognostic (2.10e-1)" "unprognostic (1.80e-1)" "unprognostic (2.80e-2)" "unprognostic (6.09e-2)" "unprognostic (8.81e-3)" "unprognostic (1.00e-2)" "unprognostic (3.45e-1)" "unprognostic (2.94e-2)" "unprognostic (3.27e-3)" "unprognostic (3.42e-2)" "unprognostic (1.02e-1)" "unprognostic (5.34e-2)" "unprognostic (1.26e-1)" "unprognostic (1.65e-1)" TRAPPC13 "C5orf44, FLJ13611, MGC48585" ENSG00000113597 "Trafficking protein particle complex subunit 13" A5PLN9 5 65625004-65666233 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037777 Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 27: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 7: Non-specific - Transcription" 11 "Nucleoplasm, Plasma membrane" "HPA037777: " "unprognostic (3.67e-1)" "unprognostic (3.66e-2)" "unprognostic (1.50e-1)" "unprognostic (4.75e-2)" "unprognostic (2.06e-3)" "unprognostic (1.52e-1)" "potential prognostic favorable (7.90e-4)" "unprognostic (1.47e-1)" "unprognostic (3.14e-1)" "potential prognostic favorable (2.99e-7)" "unprognostic (8.43e-2)" "unprognostic (3.61e-3)" "unprognostic (3.75e-2)" "unprognostic (1.81e-1)" "unprognostic (1.31e-1)" "unprognostic (3.79e-2)" "unprognostic (6.34e-2)" "unprognostic (3.09e-1)" "unprognostic (3.38e-3)" "unprognostic (4.20e-1)" "unprognostic (4.25e-3)" "unprognostic (1.95e-1)" "unprognostic (2.18e-1)" "unprognostic (2.24e-1)" "unprognostic (3.39e-1)" "unprognostic (2.01e-1)" "unprognostic (4.30e-1)" "unprognostic (2.85e-2)" "unprognostic (5.99e-2)" TRAPPC14 "C7orf43, FLJ10925, MAP11" ENSG00000146826 "Trafficking protein particle complex subunit 14" Q8WVR3 7 100154420-100158723 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 19.1;Neutrophils: 19.1;Syncytiotrophoblasts: 20.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Spleen - B-cells (Spleen), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019359, HPA029463, HPA029464" Approved Enhanced "Vesicles,Plasma membrane,Centriolar satellite" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 67: Testis - Mixed function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 39: Non-specific - Transcription" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 13 Vesicles "Plasma membrane, Centriolar satellite" "HPA019359: , HPA029463: , HPA029464: " "unprognostic (2.64e-1)" "unprognostic (7.67e-2)" "unprognostic (2.99e-1)" "unprognostic (2.91e-2)" "unprognostic (6.76e-2)" "unprognostic (5.23e-2)" "unprognostic (2.97e-1)" "unprognostic (2.75e-1)" "unprognostic (1.24e-3)" "unprognostic (4.75e-3)" "unprognostic (1.38e-1)" "unprognostic (3.27e-2)" "unprognostic (5.28e-3)" "unprognostic (3.39e-2)" "unprognostic (8.24e-2)" "unprognostic (1.04e-1)" "unprognostic (2.79e-1)" "unprognostic (1.62e-1)" "unprognostic (8.11e-2)" "unprognostic (5.03e-3)" "unprognostic (4.29e-2)" "unprognostic (2.92e-2)" "unprognostic (3.67e-2)" "unprognostic (6.40e-3)" "unprognostic (1.50e-2)" "unprognostic (1.87e-2)" "unprognostic (1.30e-1)" "unprognostic (1.79e-1)" "unprognostic (8.29e-2)" TRAPPC2 "hYP38334, MIP-2A, SEDL, SEDT, TRS20, ZNF547L" ENSG00000196459 "Trafficking protein particle complex subunit 2" P0DI81 X 13712244-13734635 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "ER-Golgi transport, Transcription, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Platelets: 132.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "CAB004665, HPA063308" Approved Approved "Nucleoplasm,Endoplasmic reticulum,Vesicles" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 64: Non-specific - Transcription" "Cluster 24: Neurons - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 65 "Endoplasmic reticulum, Vesicles" Nucleoplasm "CAB004665: , HPA063308: " "unprognostic (1.84e-1)" "unprognostic (1.46e-2)" "unprognostic (1.25e-1)" "unprognostic (2.73e-1)" "unprognostic (1.03e-1)" "unprognostic (2.20e-1)" "unprognostic (4.41e-2)" "potential prognostic favorable (2.88e-4)" "unprognostic (2.44e-2)" "unprognostic (2.76e-3)" "validated prognostic favorable (5.99e-4)" "validated prognostic favorable (6.74e-4)" "unprognostic (1.18e-1)" "unprognostic (4.85e-3)" "unprognostic (1.65e-1)" "unprognostic (7.15e-2)" "unprognostic (3.31e-1)" "unprognostic (7.81e-3)" "unprognostic (7.63e-2)" "unprognostic (2.62e-2)" "unprognostic (9.32e-2)" "unprognostic (2.52e-2)" "unprognostic (2.75e-1)" "unprognostic (1.15e-1)" "unprognostic (2.01e-1)" "unprognostic (2.37e-1)" "potential prognostic unfavorable (7.33e-4)" "unprognostic (5.11e-1)" "unprognostic (2.28e-1)" "unprognostic (1.24e-1)" "unprognostic (1.37e-1)" TRAPPC2B "MIP-2A, SEDLP, SEDLP1, TRAPPC2P1" ENSG00000256060 "Trafficking protein particle complex subunit 2B" P0DI82 19 57363551-57365405 "Predicted intracellular proteins" "ER-Golgi transport, Transcription, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Early spermatids: 22.2;Endometrial secretory cells: 4.9;Gastric chief cells: 7.6;Late primary spermatocytes: 15.2;Megakaryocytes: 6.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" HPA063308 Approved "Nucleoplasm,Endoplasmic reticulum,Vesicles" NA NA "Cluster 32: Basophils - Transcription" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 2: Neurons - Nucleosome" "Cluster 4: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 2 "Endoplasmic reticulum, Vesicles" Nucleoplasm "HPA063308: " "unprognostic (3.44e-2)" "unprognostic (6.23e-2)" "unprognostic (1.87e-1)" "unprognostic (9.22e-2)" "unprognostic (4.96e-2)" "unprognostic (6.44e-2)" "unprognostic (1.34e-2)" "unprognostic (1.03e-2)" "unprognostic (5.80e-2)" "potential prognostic favorable (7.09e-8)" "unprognostic (1.44e-2)" "unprognostic (1.60e-3)" "unprognostic (6.92e-2)" "unprognostic (1.31e-2)" "unprognostic (1.98e-1)" "unprognostic (1.92e-1)" "unprognostic (5.54e-2)" "unprognostic (8.82e-2)" "unprognostic (7.57e-2)" "unprognostic (1.04e-1)" "unprognostic (2.99e-3)" "unprognostic (1.34e-1)" "unprognostic (5.97e-2)" "unprognostic (1.66e-1)" "unprognostic (1.59e-2)" "unprognostic (1.57e-2)" "unprognostic (1.09e-1)" "unprognostic (9.80e-2)" "unprognostic (2.08e-1)" TRAPPC2L HSPC176 ENSG00000167515 "Trafficking protein particle complex subunit 2L" Q9UL33 16 88856220-88862686 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "ER-Golgi transport, Transport" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal suprabasal cells: 260.9;Hofbauer cells: 330.0;Late primary spermatocytes: 470.8;Late spermatids: 631.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041714 Approved Supported Vesicles,Cytosol NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 97: Non-specific - Cellular respiration" 39 "Vesicles, Cytosol" "HPA041714: " "unprognostic (1.72e-1)" "unprognostic (2.11e-2)" "unprognostic (2.71e-2)" "unprognostic (2.26e-2)" "unprognostic (6.29e-2)" "unprognostic (8.04e-3)" "unprognostic (1.57e-1)" "unprognostic (4.18e-2)" "unprognostic (2.13e-2)" "unprognostic (2.95e-2)" "potential prognostic favorable (1.07e-8)" "unprognostic (2.39e-1)" "unprognostic (2.68e-2)" "unprognostic (5.85e-2)" "unprognostic (1.32e-2)" "unprognostic (2.28e-1)" "unprognostic (9.28e-2)" "unprognostic (1.27e-1)" "unprognostic (4.46e-1)" "unprognostic (2.61e-2)" "unprognostic (2.93e-1)" "unprognostic (4.63e-1)" "unprognostic (2.94e-1)" "unprognostic (4.01e-1)" "unprognostic (1.53e-1)" "unprognostic (1.42e-1)" "unprognostic (7.51e-2)" "unprognostic (1.26e-1)" "unprognostic (9.66e-2)" "unprognostic (3.41e-1)" "unprognostic (9.00e-2)" TRAPPC3 BET3 ENSG00000054116 "Trafficking protein particle complex subunit 3" O43617 1 36136570-36156053 "Essential proteins, Predicted intracellular proteins" "ER-Golgi transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 259.7;Esophageal apical cells: 476.0;Esophageal suprabasal cells: 264.5;Late primary spermatocytes: 385.4;Syncytiotrophoblasts: 237.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028408 Approved Approved "Golgi apparatus,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 22: Epididymis - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 37: Non-specific - mRNA processing" "Cluster 8: Non-specific - Secretory pathway" 41 "Golgi apparatus, Cytosol" "HPA028408: " "unprognostic (2.31e-1)" "unprognostic (7.82e-2)" "potential prognostic unfavorable (3.12e-4)" "unprognostic (3.05e-2)" "unprognostic (4.87e-3)" "unprognostic (2.20e-1)" "unprognostic (1.72e-1)" "unprognostic (4.83e-2)" "unprognostic (1.51e-1)" "unprognostic (4.88e-3)" "potential prognostic favorable (4.18e-5)" "unprognostic (3.43e-3)" "unprognostic (7.32e-2)" "validated prognostic unfavorable (6.88e-10)" "validated prognostic unfavorable (6.33e-4)" "unprognostic (2.60e-1)" "unprognostic (3.20e-1)" "unprognostic (1.45e-1)" "unprognostic (2.69e-1)" "unprognostic (3.50e-2)" "unprognostic (2.48e-1)" "unprognostic (1.29e-2)" "unprognostic (1.75e-1)" "unprognostic (9.52e-2)" "unprognostic (3.05e-2)" "unprognostic (1.81e-2)" "unprognostic (1.27e-1)" "unprognostic (1.32e-1)" "unprognostic (1.49e-1)" "unprognostic (1.03e-1)" "unprognostic (1.25e-1)" TRAPPC3L "bA259P20.2, BET3L, FLJ11180" ENSG00000173626 "Trafficking protein particle complex subunit 3L" Q5T215 6 116494989-116545684 "Predicted intracellular proteins" "ER-Golgi transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 12 "Platelets: 146.5" "Cell type enhanced" "Detected in some" "endothelial cell: 3.2;hippocampal CA1-3: 3.2;lower rhombic lip: 6.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA060912 Approved "Golgi apparatus,Vesicles" NA NA "Cluster 40: Non-specific - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 56: Non-specific - Sensory perception" "Cluster 47: Platelets - Hemostasis" "Golgi apparatus, Vesicles" "HPA060912: " "unprognostic (4.56e-2)" "unprognostic (3.05e-1)" "unprognostic (1.67e-1)" "potential prognostic favorable (9.49e-4)" "unprognostic (3.92e-2)" "unprognostic (6.48e-2)" "unprognostic (9.69e-2)" "unprognostic (3.04e-1)" TRAPPC4 "PTD009, SBDN, TRS23" ENSG00000196655 "Trafficking protein particle complex subunit 4" Q9Y296 11 119018763-119025454 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 38.6;Late primary spermatocytes: 56.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039752, HPA041371" Approved Approved Cytosol NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 24: Non-specific - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" 38 Cytosol "HPA039752: , HPA041371: " "unprognostic (1.23e-1)" "unprognostic (2.85e-2)" "unprognostic (3.12e-1)" "unprognostic (1.54e-1)" "unprognostic (1.76e-1)" "unprognostic (3.96e-2)" "unprognostic (1.44e-2)" "unprognostic (8.93e-3)" "unprognostic (5.64e-3)" "unprognostic (3.15e-3)" "validated prognostic favorable (3.30e-4)" "validated prognostic favorable (2.42e-4)" "potential prognostic favorable (4.76e-5)" "potential prognostic unfavorable (2.70e-6)" "unprognostic (1.01e-2)" "unprognostic (6.86e-2)" "unprognostic (9.08e-2)" "unprognostic (1.80e-2)" "unprognostic (1.43e-1)" "unprognostic (1.83e-1)" "unprognostic (1.78e-1)" "unprognostic (1.15e-1)" "unprognostic (3.66e-2)" "unprognostic (2.62e-2)" "unprognostic (3.36e-1)" "unprognostic (6.82e-2)" "unprognostic (3.18e-1)" "unprognostic (3.09e-1)" "unprognostic (2.92e-1)" "unprognostic (3.85e-2)" "unprognostic (1.11e-2)" TRAPPC5 "MGC52424, TRS31" ENSG00000181029 "Trafficking protein particle complex subunit 5" Q8IUR0 19 7680833-7687703 "Essential proteins, Predicted intracellular proteins" "ER-Golgi transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 31.5;Brain inhibitory neurons: 29.8;Late spermatids: 52.7;Oligodendrocytes: 30.2;Other brain neurons: 42.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042221, HPA049064" Uncertain Approved Vesicles NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 23: Non-specific - Transcription" "Cluster 98: Neurons - Neurotransmission & signaling" 33 Vesicles "HPA042221: , HPA049064: " "unprognostic (1.29e-1)" "unprognostic (2.47e-1)" "unprognostic (7.35e-2)" "potential prognostic favorable (6.47e-5)" "unprognostic (1.77e-1)" "unprognostic (1.25e-1)" "unprognostic (1.68e-1)" "unprognostic (1.60e-2)" "unprognostic (9.94e-3)" "unprognostic (3.24e-1)" "unprognostic (1.70e-2)" "unprognostic (2.48e-3)" "unprognostic (4.83e-2)" "unprognostic (5.22e-3)" "unprognostic (1.65e-1)" "unprognostic (2.05e-1)" "unprognostic (1.26e-1)" "unprognostic (1.19e-2)" "unprognostic (1.72e-1)" "unprognostic (5.37e-3)" "unprognostic (7.73e-2)" "unprognostic (1.26e-2)" "unprognostic (1.54e-1)" "unprognostic (4.66e-2)" "unprognostic (2.25e-1)" "unprognostic (1.47e-1)" "unprognostic (7.32e-3)" "unprognostic (1.89e-2)" "unprognostic (2.69e-1)" "unprognostic (3.46e-3)" "unprognostic (2.26e-1)" TRAPPC6A "HSPC289, MGC2650, TRS33" ENSG00000007255 "Trafficking protein particle complex subunit 6A" O75865 19 45162928-45178237 "Predicted intracellular proteins" "ER-Golgi transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 159.3;Late spermatids: 163.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Prostate - Prostate glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043043 Approved NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 97: Non-specific - Cellular respiration" 9 "HPA043043: " "unprognostic (1.63e-2)" "unprognostic (8.43e-2)" "unprognostic (1.34e-1)" "unprognostic (2.79e-1)" "unprognostic (1.69e-1)" "unprognostic (1.95e-1)" "unprognostic (1.30e-1)" "unprognostic (2.38e-1)" "unprognostic (2.08e-1)" "unprognostic (2.05e-1)" "potential prognostic favorable (5.60e-7)" "unprognostic (6.48e-2)" "unprognostic (3.97e-3)" "unprognostic (7.58e-2)" "unprognostic (1.53e-1)" "unprognostic (2.14e-1)" "unprognostic (3.22e-1)" "unprognostic (6.23e-3)" "unprognostic (2.84e-1)" "unprognostic (5.05e-1)" "unprognostic (2.43e-1)" "unprognostic (1.47e-1)" "unprognostic (2.53e-3)" "unprognostic (1.53e-1)" "unprognostic (2.04e-1)" "unprognostic (6.53e-2)" "unprognostic (2.86e-1)" "unprognostic (7.73e-3)" "unprognostic (9.66e-2)" "unprognostic (4.50e-2)" "unprognostic (2.36e-2)" TRAPPC6B ENSG00000182400 "Trafficking protein particle complex subunit 6B" Q86SZ2 14 39147811-39170532 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Neurogenesis "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 136.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047928 Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 27: Cerebellum - Synaptic function" "Cluster 14: Neurons - Synaptic function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 7: Non-specific - Transcription" 24 "Endoplasmic reticulum" "HPA047928: " "unprognostic (2.97e-1)" "unprognostic (1.03e-1)" "unprognostic (1.47e-3)" "unprognostic (9.07e-2)" "unprognostic (1.97e-1)" "unprognostic (1.63e-1)" "unprognostic (1.39e-1)" "unprognostic (6.16e-2)" "unprognostic (3.07e-2)" "unprognostic (5.14e-1)" "potential prognostic favorable (1.42e-4)" "unprognostic (2.85e-3)" "unprognostic (1.82e-1)" "unprognostic (1.13e-3)" "unprognostic (7.18e-2)" "unprognostic (1.34e-1)" "unprognostic (2.40e-2)" "unprognostic (6.71e-2)" "unprognostic (2.28e-1)" "unprognostic (3.35e-1)" "unprognostic (1.08e-1)" "unprognostic (2.17e-1)" "unprognostic (2.88e-3)" "unprognostic (5.61e-3)" "unprognostic (3.69e-1)" "unprognostic (1.59e-1)" "unprognostic (3.51e-3)" "unprognostic (1.10e-1)" "unprognostic (3.34e-1)" "unprognostic (8.31e-2)" "unprognostic (2.48e-1)" TRAPPC8 "GSG1, HsT2706, KIAA1012, TRS85" ENSG00000153339 "Trafficking protein particle complex subunit 8" Q9Y2L5 18 31829197-31953136 "Essential proteins, Predicted intracellular proteins" "ER-Golgi transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 255.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 8.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041107 Approved Approved Microtubules,Cytosol NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 39: Testis - Nuclear processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 13: Non-specific - Mixed function" "Cluster 7: Non-specific - Transcription" 23 Cytosol Microtubules "HPA041107: " "unprognostic (5.07e-2)" "unprognostic (2.95e-1)" "unprognostic (6.91e-2)" "unprognostic (1.30e-1)" "unprognostic (3.46e-1)" "unprognostic (1.20e-1)" "potential prognostic favorable (7.14e-4)" "unprognostic (3.21e-2)" "unprognostic (3.07e-1)" "validated prognostic favorable (1.30e-6)" "validated prognostic favorable (3.35e-4)" "unprognostic (2.42e-2)" "unprognostic (3.00e-1)" "unprognostic (1.77e-1)" "unprognostic (2.53e-1)" "unprognostic (1.23e-1)" "unprognostic (1.24e-1)" "unprognostic (1.49e-1)" "unprognostic (2.32e-1)" "unprognostic (5.84e-2)" "unprognostic (1.42e-1)" "potential prognostic unfavorable (4.01e-4)" "unprognostic (7.72e-2)" "unprognostic (7.01e-2)" "unprognostic (8.16e-2)" "unprognostic (1.80e-1)" "unprognostic (5.26e-2)" "unprognostic (1.21e-1)" "unprognostic (4.45e-1)" "unprognostic (3.53e-2)" TRAPPC9 "IKBKBBP, KIAA1882, MRT13, NIBP, T1, TRS120" ENSG00000167632 "Trafficking protein particle complex subunit 9" Q96Q05 8 139727725-140458579 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Differentiation "Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Lactotrophs: 886.2;Somatotrophs: 744.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pituitary gland - Lactotropes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026579 Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 22 "Golgi apparatus, Vesicles" Nucleoplasm "HPA026579: " "unprognostic (1.17e-1)" "unprognostic (5.37e-3)" "unprognostic (2.30e-1)" "unprognostic (6.02e-2)" "unprognostic (5.81e-2)" "unprognostic (2.76e-1)" "unprognostic (3.76e-1)" "unprognostic (3.26e-2)" "unprognostic (3.38e-1)" "unprognostic (4.15e-2)" "unprognostic (1.43e-3)" "unprognostic (1.34e-1)" "unprognostic (7.71e-2)" "unprognostic (2.62e-1)" "unprognostic (2.97e-2)" "unprognostic (4.89e-3)" "unprognostic (5.92e-2)" "unprognostic (8.17e-3)" "unprognostic (3.90e-3)" "unprognostic (1.16e-1)" "unprognostic (3.69e-1)" "unprognostic (7.50e-2)" "unprognostic (5.26e-3)" "unprognostic (1.77e-1)" "unprognostic (2.02e-1)" "unprognostic (2.24e-1)" "unprognostic (2.61e-1)" "unprognostic (1.61e-1)" "unprognostic (1.78e-1)" "unprognostic (1.81e-1)" "unprognostic (4.22e-1)" TRARG1 "BEC-1, DSPB1, IFITMD3, LOST1, TUSC5" ENSG00000184811 "Trafficking regulator of GLUT4 (SLC2A4) 1" Q8IXB3 17 1279662-1300978 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adipose tissue: 95.3;breast: 67.7" "Cell type enriched" "Detected in some" 44 "Adipocytes: 87.4" "Cell type enhanced" "Detected in single" "vascular associated smooth muscle cell: 1.1" "Cancer enriched" "Detected in single" 6 "Breast Invasive Carcinoma (TCGA): 2.4" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Minor Salivary Gland - Adipocytes (Minor salivary gland), Skin - Adipocytes (Skin)" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA050825 Approved NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 89: Adipocytes - Lipid metabolism" 1 "HPA050825: " "unprognostic (3.35e-2)" TRAT1 "HSPC062, TCRIM, TRIM" ENSG00000163519 "T cell receptor associated transmembrane adaptor 1" Q6PIZ9 3 108822770-108855005 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 26 "lymphoid tissue: 74.3" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 18.6;Innate lymphoid cells: 24.1;NK-cells: 42.1;T-cells: 145.4;Thymocytes: 52.5" "Cell type enriched" "Detected in single" 67 "leukocyte: 56.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "basophil: 396.7" "Group enriched" "Detected in many" 155 "granulocytes: 396.7;T-cells: 314.1" "Cancer enhanced" "Detected in some" "Leukemia: 10.3;Myeloma: 2.8" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Kidney - T-cells, Liver - T-cells, Minor Salivary Gland - T-cells, Prostate - T-cells, Skin - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA002356, CAB026130, HPA072760" Enhanced Enhanced "Plasma membrane,Mitotic spindle,Centriolar satellite" Yes NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 80: Thymus - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" 2 "Plasma membrane" "Mitotic spindle, Centriolar satellite" "CAB026130: , HPA002356: , HPA072760: " "unprognostic (1.02e-3)" "unprognostic (6.87e-2)" "potential prognostic favorable (5.68e-4)" "unprognostic (2.66e-1)" "unprognostic (1.01e-1)" "unprognostic (8.96e-2)" "unprognostic (1.92e-2)" "unprognostic (1.26e-2)" "unprognostic (8.25e-2)" "unprognostic (2.34e-1)" "unprognostic (1.78e-1)" "unprognostic (6.86e-2)" "potential prognostic unfavorable (4.49e-4)" "unprognostic (2.94e-1)" "unprognostic (1.71e-1)" "unprognostic (2.41e-2)" TRAV1-1 "TCRAV1S1, TCRAV7S1, TRAV11" ENSG00000255569 "T cell receptor alpha variable 1-1" A0A0B4J248 14 21621838-21622567 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 13 "lymphoid tissue: 16.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 18 "MAIT T-cell: 26.1;memory CD4 T-cell: 11.8;memory CD8 T-cell: 27.1;naive CD4 T-cell: 17.8;naive CD8 T-cell: 25.8;T-reg: 30.7" "Lineage enriched" "Detected in many" 24 "T-cells: 30.7" "Cancer enhanced" "Detected in some" "Bone cancer: 1.0;Leukemia: 2.6" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 80: Thymus - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (1.62e-1)" "unprognostic (3.45e-1)" "unprognostic (2.64e-1)" TRAV1-2 ENSG00000256553 "T cell receptor alpha variable 1-2" A0A0B4J238 14 21642889-21643578 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 6 "lymphoid tissue: 17.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 7 "MAIT T-cell: 2033.2" "Lineage enriched" "Detected in many" 504 "T-cells: 2033.2" "Cancer enriched" "Detected in some" 19 "Bone cancer: 110.9" "Adipose visceral - T-cells, Lung - T-cells" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (1.26e-2)" "unprognostic (2.66e-2)" "unprognostic (5.03e-2)" "unprognostic (1.15e-1)" "unprognostic (5.53e-2)" "unprognostic (5.20e-2)" "unprognostic (1.17e-1)" "unprognostic (4.25e-1)" "unprognostic (5.29e-2)" TRAV10 "TCRAV10S1, TCRAV24S1" ENSG00000211784 "T cell receptor alpha variable 10" A0A0B4J240 14 21825472-21826075 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 16 "lymphoid tissue: 15.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 64 "MAIT T-cell: 24.8;memory CD4 T-cell: 38.4;memory CD8 T-cell: 43.3;naive CD4 T-cell: 42.7;naive CD8 T-cell: 25.1;T-reg: 59.6" "Lineage enriched" "Detected in single" 155 "T-cells: 59.6" "Cancer enriched" "Detected in single" 12 "Leukemia: 1.4" "Not detected" "Not detected" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 6: Leukemia - Signal transduction" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (3.40e-2)" "unprognostic (6.18e-1)" TRAV12-1 ENSG00000211785 "T cell receptor alpha variable 12-1" A0A0B4J245 14 21841240-21841774 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 19.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 71 "MAIT T-cell: 128.9;memory CD4 T-cell: 206.0;memory CD8 T-cell: 200.0;naive CD4 T-cell: 139.2;naive CD8 T-cell: 252.7;T-reg: 194.7" "Lineage enriched" "Detected in many" 96 "T-cells: 252.7" "Cancer enriched" "Detected in single" 211 "Leukemia: 21.0" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells, Spleen - T-cells, Thyroid gland - T-cells" NA NA "Cluster 27: T-cells - Unknown function" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (4.06e-2)" "unprognostic (3.08e-3)" "unprognostic (1.67e-1)" "unprognostic (2.00e-1)" "unprognostic (6.03e-2)" "unprognostic (6.61e-2)" "unprognostic (9.22e-2)" "unprognostic (3.67e-2)" "unprognostic (7.26e-3)" "unprognostic (3.15e-1)" "unprognostic (1.50e-1)" "unprognostic (4.19e-1)" "unprognostic (1.20e-1)" "unprognostic (3.22e-2)" "unprognostic (3.67e-2)" "unprognostic (6.03e-2)" "unprognostic (2.07e-1)" "unprognostic (5.67e-2)" "unprognostic (5.25e-1)" TRAV12-2 ENSG00000211789 "T cell receptor alpha variable 12-2" A0A075B6T6 14 21887857-21888502 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 20.8" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 17 "memory CD4 T-cell: 102.3;memory CD8 T-cell: 87.7;naive CD4 T-cell: 90.7;naive CD8 T-cell: 65.5;T-reg: 143.7" "Lineage enriched" "Detected in many" 76 "T-cells: 143.7" "Cancer enriched" "Detected in single" 258 "lymphoma: 25.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells, Minor Salivary Gland - T-cells, Spleen - T-cells" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (3.20e-1)" "unprognostic (6.36e-3)" "potential prognostic favorable (8.65e-4)" "unprognostic (2.40e-1)" "unprognostic (2.98e-1)" "potential prognostic favorable (5.40e-4)" "unprognostic (4.03e-2)" "unprognostic (2.60e-2)" "unprognostic (2.02e-2)" "unprognostic (3.11e-3)" "unprognostic (3.87e-2)" "unprognostic (1.43e-1)" "unprognostic (4.03e-1)" "unprognostic (1.67e-1)" "unprognostic (1.18e-2)" "unprognostic (1.50e-2)" "unprognostic (1.74e-1)" "unprognostic (4.09e-3)" "unprognostic (3.78e-2)" TRAV12-3 "TCRAV12S3, TCRAV2S2, TRAV123" ENSG00000211794 "T cell receptor alpha variable 12-3" A0A0B4J271 14 21965451-21966061 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "lymphoid tissue: 55.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "memory CD4 T-cell: 187.2;T-reg: 257.5" "Lineage enriched" "Detected in many" 23 "T-cells: 257.5" "Not detected" "Not detected" "Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells, Spleen - T-cells, Thyroid gland - T-cells" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 80: Thymus - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" "potential prognostic favorable (2.09e-4)" "unprognostic (2.17e-3)" "unprognostic (6.87e-2)" "unprognostic (8.50e-2)" "unprognostic (4.50e-3)" "unprognostic (4.06e-1)" "unprognostic (3.07e-2)" "unprognostic (2.93e-2)" "unprognostic (1.65e-1)" "unprognostic (2.53e-1)" "unprognostic (5.53e-2)" "unprognostic (2.98e-1)" "unprognostic (1.46e-1)" "unprognostic (2.45e-1)" "unprognostic (4.45e-2)" TRAV13-1 ENSG00000211788 "T cell receptor alpha variable 13-1" A0A0B4J241 14 21868839-21869365 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "lymphoid tissue: 58.1" "Cell type enriched" "Detected in single" 5 "T-cells: 1.5" "Cell type enriched" "Detected in single" 16 "leukocyte: 1.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 330.5" "Lineage enriched" "Detected in many" 28 "T-cells: 330.5" "Not detected" "Not detected" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells, Minor Salivary Gland - T-cells, Pituitary gland - T-cells, Skin - T-cells, Spleen - T-cells, Thyroid gland - T-cells" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (3.08e-1)" "unprognostic (3.55e-3)" "unprognostic (4.85e-3)" "unprognostic (2.52e-1)" "unprognostic (1.53e-1)" "potential prognostic favorable (2.86e-5)" "unprognostic (1.50e-1)" "unprognostic (1.17e-1)" "unprognostic (2.03e-2)" "unprognostic (7.16e-3)" "unprognostic (5.93e-3)" "unprognostic (2.85e-1)" "unprognostic (1.37e-1)" "unprognostic (1.11e-2)" "unprognostic (4.15e-2)" "unprognostic (8.17e-2)" "unprognostic (6.54e-2)" "unprognostic (2.70e-2)" "unprognostic (2.49e-3)" "unprognostic (1.48e-1)" "unprognostic (2.26e-1)" "unprognostic (2.65e-2)" "unprognostic (4.71e-1)" TRAV13-2 ENSG00000211791 "T cell receptor alpha variable 13-2" A0A0B4J235 14 21918188-21918756 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 24 "lymphoid tissue: 48.1" "Cell type enhanced" "Detected in some" "Breast hormone-responsive cells: 1.6;NK-cells: 1.1;T-cells: 3.0" "Cell type enriched" "Detected in single" 12 "leukocyte: 1.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 38 "MAIT T-cell: 33.0;memory CD4 T-cell: 94.4;memory CD8 T-cell: 57.4;naive CD4 T-cell: 102.2;naive CD8 T-cell: 114.5;T-reg: 115.2" "Lineage enriched" "Detected in many" 52 "T-cells: 115.2" "Cancer enhanced" "Detected in some" "lymphoma: 2.5;Rhabdoid: 1.0" "Adipose visceral - T-cells, Lung - T-cells, Spleen - T-cells, Thyroid gland - T-cells" NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 80: Thymus - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (9.73e-3)" "unprognostic (1.05e-2)" "unprognostic (1.13e-1)" "unprognostic (2.11e-1)" "unprognostic (1.90e-1)" "unprognostic (2.60e-2)" "unprognostic (7.01e-3)" "unprognostic (8.49e-2)" "unprognostic (4.42e-2)" "unprognostic (2.35e-1)" "unprognostic (1.21e-2)" TRAV14DV4 "hADV14S1, TCRAV6S1-hDV104S1, TRAV14/DV4" ENSG00000211792 "T cell receptor alpha variable 14/delta variable 4" A0A0A6YYC5 14 21924063-21924651 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "lymphoid tissue: 23.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "memory CD4 T-cell: 38.4;memory CD8 T-cell: 78.1;naive CD4 T-cell: 30.8;naive CD8 T-cell: 122.8;T-reg: 42.8" "Lineage enriched" "Detected in single" 175 "T-cells: 122.8" "Not detected" "Not detected" "Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells" NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (1.12e-2)" "unprognostic (5.04e-3)" "unprognostic (1.75e-1)" "unprognostic (9.26e-2)" "unprognostic (2.00e-2)" "unprognostic (1.42e-3)" "unprognostic (2.82e-1)" "unprognostic (3.24e-1)" "unprognostic (3.14e-2)" "unprognostic (2.71e-1)" "unprognostic (4.25e-2)" TRAV16 "TCRAV16S1, TCRAV9S1" ENSG00000211796 "T cell receptor alpha variable 16" A0A0A6YYK6 14 21990496-21990938 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 10 "lymphoid tissue: 37.0" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 48.2;T-reg: 58.3" "Lineage enriched" "Detected in single" 163 "T-cells: 58.3" "Cancer enhanced" "Detected in some" "lymphoma: 6.7;Rhabdoid: 1.9" "Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells, Spleen - T-cells" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (4.43e-2)" "unprognostic (1.83e-1)" "unprognostic (2.28e-1)" "unprognostic (8.94e-2)" "unprognostic (1.14e-1)" "unprognostic (2.10e-1)" "unprognostic (9.30e-2)" "unprognostic (2.98e-2)" "unprognostic (1.38e-1)" "unprognostic (1.40e-1)" "unprognostic (5.67e-2)" TRAV17 "TCRAV17S1, TCRAV3S1" ENSG00000211797 "T cell receptor alpha variable 17" A0A0B4J275 14 21997539-21998168 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "lymphoid tissue: 25.9" "Group enriched" "Detected in some" 6 "Medullary thymic epithelial cells: 2.4;T-cells: 4.0;Thymic myoid cells: 1.4" "Cell type enriched" "Detected in single" 17 "leukocyte: 1.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 19 "memory CD4 T-cell: 81.7;memory CD8 T-cell: 63.7;naive CD4 T-cell: 62.0;naive CD8 T-cell: 53.4;T-reg: 116.7" "Lineage enriched" "Detected in single" 225 "T-cells: 116.7" "Cancer enhanced" "Detected in single" "Rhabdoid: 1.5" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells, Spleen - T-cells" "Not detected" "Not detected" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (7.51e-2)" "unprognostic (6.74e-3)" "unprognostic (4.10e-2)" "potential prognostic favorable (5.31e-5)" "unprognostic (3.58e-1)" "unprognostic (1.45e-1)" "unprognostic (1.35e-2)" "unprognostic (1.44e-1)" "unprognostic (7.20e-2)" "unprognostic (2.80e-1)" "unprognostic (8.32e-2)" "unprognostic (3.46e-1)" "unprognostic (3.84e-3)" TRAV18 TCRAV18S1 ENSG00000211798 "T cell receptor alpha variable 18" A0A075B6X5 14 22003106-22003673 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 12 "lymphoid tissue: 9.1" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Kidney Chromophobe (TCGA): 1.1" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "memory CD4 T-cell: 5.6;memory CD8 T-cell: 6.3;naive CD4 T-cell: 12.4;naive CD8 T-cell: 7.9;T-reg: 5.1" "Lineage enriched" "Detected in single" 125 "T-cells: 12.4" "Cancer enhanced" "Detected in single" "Leukemia: 2.3" "Not detected" "Not detected" NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 80: Thymus - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 82: Dendritic cells - Antigen presentation" "unprognostic (1.62e-1)" "unprognostic (1.84e-2)" "unprognostic (3.80e-1)" TRAV19 "TCRAV12S1, TCRAV19S1" ENSG00000211799 "T cell receptor alpha variable 19" A0A0A6YYK7 14 22007512-22008181 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "lymphoid tissue: 34.3" "Cell type enhanced" "Detected in single" "T-cells: 1.1" "Cell type enriched" "Detected in single" 14 "leukocyte: 1.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 10 "memory CD4 T-cell: 17.9;memory CD8 T-cell: 45.6;naive CD4 T-cell: 23.3;naive CD8 T-cell: 24.6;T-reg: 24.0" "Lineage enriched" "Detected in single" 172 "T-cells: 45.6" "Cancer enriched" "Detected in single" 80 "Leukemia: 35.8" "Adipose visceral - T-cells, Lung - T-cells, Spleen - T-cells" "Not detected" "Not detected" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (5.07e-3)" "unprognostic (1.04e-1)" "unprognostic (8.56e-2)" "unprognostic (1.37e-3)" "unprognostic (4.31e-2)" "unprognostic (2.88e-1)" "unprognostic (4.37e-2)" "unprognostic (2.21e-1)" "unprognostic (2.66e-1)" "unprognostic (4.44e-1)" "unprognostic (4.93e-2)" "unprognostic (3.72e-2)" "unprognostic (2.39e-2)" "unprognostic (7.09e-2)" "unprognostic (4.46e-2)" "unprognostic (1.44e-1)" TRAV2 ENSG00000211776 "T cell receptor alpha variable 2" A0A0B4J234 14 21712321-21712843 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 20 "lymphoid tissue: 52.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 41.0" "Lineage enriched" "Detected in single" 124 "T-cells: 41.0" "Group enriched" "Detected in some" 5 "Leukemia: 12.5;lymphoma: 8.1" "Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells, Thyroid gland - T-cells" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 80: Thymus - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (8.07e-2)" "unprognostic (7.42e-2)" "unprognostic (2.12e-1)" "unprognostic (1.15e-1)" "potential prognostic favorable (4.16e-4)" "unprognostic (1.65e-1)" "unprognostic (1.76e-2)" "unprognostic (3.40e-2)" "unprognostic (4.32e-2)" "unprognostic (2.15e-1)" "unprognostic (1.84e-1)" "unprognostic (9.61e-2)" "unprognostic (2.44e-1)" "unprognostic (3.57e-2)" "unprognostic (2.93e-1)" "unprognostic (2.58e-2)" TRAV20 ENSG00000211800 "T cell receptor alpha variable 20" A0A0B4J274 14 22040594-22041153 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "lymphoid tissue: 13.5" "Cell type enriched" "Detected in single" 12 "T-cells: 1.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Group enriched" "Detected in many" 8 "memory CD4 T-cell: 124.6;memory CD8 T-cell: 94.6;naive CD4 T-cell: 125.1;naive CD8 T-cell: 98.3;T-reg: 152.8" "Lineage enriched" "Detected in many" 60 "T-cells: 152.8" "Not detected" "Not detected" "Spleen - T-cells" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (1.82e-1)" "unprognostic (1.11e-1)" "unprognostic (2.15e-1)" "unprognostic (1.38e-1)" TRAV21 ENSG00000211801 "T cell receptor alpha variable 21" A0A0B4J279 14 22052514-22053056 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "lymphoid tissue: 58.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 14 "memory CD4 T-cell: 221.3;memory CD8 T-cell: 233.8;naive CD4 T-cell: 199.4;naive CD8 T-cell: 205.5;T-reg: 393.4" "Lineage enriched" "Detected in many" 75 "T-cells: 393.4" "Not detected" "Not detected" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells, Spleen - T-cells" "Not detected" "Not detected" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 80: Thymus - Adaptive immune response" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (3.40e-1)" "potential prognostic favorable (6.47e-4)" "unprognostic (2.59e-2)" "unprognostic (9.85e-2)" "unprognostic (1.93e-1)" "potential prognostic favorable (9.19e-4)" "unprognostic (4.60e-2)" "unprognostic (3.05e-1)" "unprognostic (8.78e-3)" "potential prognostic favorable (4.15e-4)" "unprognostic (1.34e-1)" "unprognostic (1.46e-1)" "unprognostic (1.08e-2)" "unprognostic (4.72e-2)" "unprognostic (2.67e-2)" "unprognostic (4.39e-3)" "unprognostic (1.02e-1)" "unprognostic (9.87e-2)" "unprognostic (3.02e-1)" "unprognostic (3.01e-2)" "unprognostic (4.55e-1)" TRAV22 "TCRAV13S1, TCRAV22S1" ENSG00000211802 "T cell receptor alpha variable 22" A0A0B4J277 14 22070557-22071208 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "lymphoid tissue: 21.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 59.8" "Lineage enriched" "Detected in many" 6 "T-cells: 59.8" "Cancer enhanced" "Detected in some" "Leukemia: 1.3;Myeloma: 1.2" "Lung - T-cells" "Not detected" "Not detected" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 80: Thymus - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (2.76e-1)" "unprognostic (4.42e-1)" "unprognostic (3.24e-2)" "unprognostic (6.62e-3)" "unprognostic (2.83e-3)" TRAV23DV6 "TCRAV17S1, TRAV23/DV6" ENSG00000211803 "T cell receptor alpha variable 23/delta variable 6" A0A075B6W5 14 22086407-22086961 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 12 "lymphoid tissue: 24.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "memory CD4 T-cell: 79.5;naive CD4 T-cell: 85.9;T-reg: 65.8" "Lineage enriched" "Detected in many" 56 "T-cells: 85.9" "Cancer enriched" "Detected in single" 351 "Leukemia: 35.1" "Adipose visceral - T-cells, Lung - T-cells, Spleen - T-cells" "Not detected" "Not detected" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (1.60e-3)" "unprognostic (4.19e-2)" "unprognostic (5.41e-2)" "potential prognostic favorable (1.54e-4)" "unprognostic (1.10e-1)" "unprognostic (1.19e-1)" "unprognostic (2.44e-1)" "unprognostic (7.41e-2)" "unprognostic (6.58e-2)" TRAV24 ENSG00000211805 "T cell receptor alpha variable 24" A0A0B4J272 14 22105343-22105846 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "lymphoid tissue: 19.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 24 "memory CD4 T-cell: 24.5;memory CD8 T-cell: 47.5;naive CD4 T-cell: 22.5;naive CD8 T-cell: 66.8;T-reg: 41.1" "Lineage enriched" "Detected in single" 242 "T-cells: 66.8" "Not detected" "Not detected" NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 80: Thymus - Adaptive immune response" "Cluster 38: Sub-cortical - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (4.82e-2)" "unprognostic (2.77e-1)" "unprognostic (8.08e-2)" "unprognostic (1.68e-2)" "unprognostic (4.72e-2)" TRAV25 "TCRAV25S1, TCRAV32S1" ENSG00000211806 "T cell receptor alpha variable 25" A0A0B4J276 14 22112347-22113031 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 9 "lymphoid tissue: 14.2" "Cell type enriched" "Detected in single" 7 "T-cells: 1.2" "Cell type enriched" "Detected in single" 22 "leukocyte: 2.2" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 63 "memory CD4 T-cell: 33.6;memory CD8 T-cell: 20.9;naive CD4 T-cell: 32.8;naive CD8 T-cell: 22.6;T-reg: 49.5" "Lineage enriched" "Detected in single" 402 "T-cells: 49.5" "Not detected" "Not detected" "Lung - T-cells, Spleen - T-cells" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (8.40e-2)" "unprognostic (4.00e-1)" "unprognostic (2.00e-1)" "unprognostic (4.79e-2)" TRAV26-1 ENSG00000211807 "T cell receptor alpha variable 26-1" A0A087WT03 14 22123318-22124285 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "lymphoid tissue: 13.0" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "memory CD4 T-cell: 37.6;naive CD4 T-cell: 39.8;T-reg: 55.9" "Lineage enriched" "Detected in single" 69 "T-cells: 55.9" "Not detected" "Not detected" "Lung - T-cells, Spleen - T-cells" "Not detected" "Not detected" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (1.99e-2)" "unprognostic (5.04e-1)" "unprognostic (3.50e-1)" "unprognostic (2.60e-1)" "unprognostic (2.44e-1)" "unprognostic (4.62e-1)" "unprognostic (1.15e-2)" TRAV26-2 "TCRAV26S2, TCRAV4S1, TRAV262" ENSG00000211812 "T cell receptor alpha variable 26-2" A0A0B4J265 14 22202583-22203368 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 29 "lymphoid tissue: 38.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 35 "memory CD4 T-cell: 53.0;memory CD8 T-cell: 80.5;naive CD4 T-cell: 51.1;naive CD8 T-cell: 36.9;T-reg: 66.5" "Lineage enriched" "Detected in single" 120 "T-cells: 80.5" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 80: Thymus - Adaptive immune response" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 9: T-cells - Adaptive immunity: Regulation" "potential prognostic favorable (9.95e-4)" "unprognostic (8.99e-2)" "unprognostic (1.52e-1)" "unprognostic (2.60e-2)" "unprognostic (9.98e-3)" "unprognostic (5.42e-2)" "unprognostic (3.46e-2)" "unprognostic (6.32e-3)" TRAV27 ENSG00000211809 "T cell receptor alpha variable 27" A0A087WT01 14 22147995-22148633 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "lymphoid tissue: 18.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 19 "memory CD4 T-cell: 51.7;memory CD8 T-cell: 59.0;naive CD4 T-cell: 60.6;naive CD8 T-cell: 59.3;T-reg: 82.1" "Lineage enriched" "Detected in many" 62 "T-cells: 82.1" "Cancer enhanced" "Detected in single" "Leukemia: 1.4" "Adipose visceral - T-cells, Lung - T-cells, Spleen - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 80: Thymus - Adaptive immune response" "Cluster 6: Leukemia - Signal transduction" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (3.41e-1)" "unprognostic (2.94e-2)" "unprognostic (7.30e-2)" "unprognostic (2.15e-1)" "unprognostic (5.05e-2)" TRAV29DV5 TRAV29/DV5 ENSG00000211810 "T cell receptor alpha variable 29/delta variable 5" P04437 14 22163238-22163870 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "lymphoid tissue: 24.8" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 20 "leukocyte: 2.1" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 20 "memory CD4 T-cell: 99.6;memory CD8 T-cell: 126.5;naive CD4 T-cell: 105.9;naive CD8 T-cell: 66.6;T-reg: 124.3" "Lineage enriched" "Detected in single" 128 "T-cells: 126.5" "Not detected" "Not detected" "Adipose visceral - T-cells, Lung - T-cells, Prostate - T-cells, Skin - T-cells, Spleen - T-cells" "Not detected" "Not detected" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 5: Rhabdoid - Unknown function" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (2.69e-2)" "unprognostic (3.54e-1)" "unprognostic (6.90e-2)" "unprognostic (1.61e-1)" "unprognostic (1.53e-1)" "unprognostic (1.67e-1)" "unprognostic (8.49e-2)" "unprognostic (9.32e-2)" "unprognostic (2.07e-2)" "unprognostic (1.92e-1)" "unprognostic (2.69e-2)" TRAV3 ENSG00000211777 "T cell receptor alpha variable 3" A0A0B4J244 14 21723713-21724321 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 9.4" "Cell type enhanced" "Detected in single" "Early primary spermatocytes: 2.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 4 "memory CD4 T-cell: 48.9;memory CD8 T-cell: 33.6;naive CD4 T-cell: 51.3;naive CD8 T-cell: 48.0;T-reg: 113.1" "Lineage enriched" "Detected in single" 144 "T-cells: 113.1" "Group enriched" "Detected in some" 20 "Bone cancer: 14.6;Leukemia: 10.8" "Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells, Spleen - T-cells" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 38: Sub-cortical - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (5.46e-3)" "unprognostic (4.87e-2)" "unprognostic (1.13e-1)" "potential prognostic favorable (1.88e-4)" "unprognostic (1.75e-1)" "unprognostic (3.05e-1)" "unprognostic (9.35e-2)" "unprognostic (2.24e-1)" "unprognostic (1.14e-1)" TRAV30 ENSG00000259092 "T cell receptor alpha variable 30" A0A087WSZ9 14 22168429-22168988 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 6 "lymphoid tissue: 12.7" "Cell type enhanced" "Detected in single" "Epididymal efferent duct absorptive cells: 1.1" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "Kidney Renal Clear Cell Carcinoma (TCGA): 29.2;Kidney Renal Papillary Cell Carcinoma (TCGA): 8.6" "Not detected" "Not detected" "Group enriched" "Detected in many" 19 "memory CD4 T-cell: 23.5;memory CD8 T-cell: 21.4;naive CD4 T-cell: 35.7;naive CD8 T-cell: 22.9;T-reg: 42.5" "Lineage enriched" "Detected in many" 28 "T-cells: 42.5" "Cancer enhanced" "Detected in some" "Rhabdoid: 8.4;Uterine cancer: 4.8" NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 5: Rhabdoid - Unknown function" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (5.11e-2)" "unprognostic (1.55e-1)" "unprognostic (2.58e-1)" "unprognostic (1.25e-2)" "unprognostic (8.76e-2)" "unprognostic (8.85e-2)" "unprognostic (1.98e-1)" "unprognostic (3.07e-1)" "unprognostic (2.95e-2)" "unprognostic (9.23e-2)" "unprognostic (6.63e-2)" "unprognostic (2.45e-1)" TRAV34 "TCRAV26S1, TCRAV34S1" ENSG00000211813 "T cell receptor alpha variable 34" A0A0B4J273 14 22207522-22208129 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 19 "lymphoid tissue: 12.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 71 "memory CD4 T-cell: 9.9;memory CD8 T-cell: 4.5;naive CD4 T-cell: 14.0;naive CD8 T-cell: 5.0;T-reg: 16.9" "Lineage enriched" "Detected in single" 170 "T-cells: 16.9" "Cancer enriched" "Detected in single" 4 "lymphoma: 2.5" "Not detected" "Not detected" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 80: Thymus - Adaptive immune response" "Cluster 46: Brainstem - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 9: T-cells - Adaptive immunity: Regulation" TRAV36DV7 TRAV36/DV7 ENSG00000211815 "T cell receptor alpha variable 36/delta variable 7" A0A075B6V5 14 22226746-22227254 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 18 "lymphoid tissue: 25.5" "Cell type enhanced" "Detected in single" "T-cells: 1.0" "Cell type enriched" "Detected in single" 19 "leukocyte: 2.0" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 8 "memory CD4 T-cell: 29.3;memory CD8 T-cell: 21.9;naive CD4 T-cell: 37.7;naive CD8 T-cell: 23.1;T-reg: 50.3" "Lineage enriched" "Detected in many" 13 "T-cells: 50.3" "Cancer enhanced" "Detected in single" "lymphoma: 1.4" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 80: Thymus - Adaptive immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (1.42e-1)" "unprognostic (2.93e-1)" "unprognostic (1.65e-2)" "unprognostic (1.15e-2)" "unprognostic (5.65e-2)" "unprognostic (2.51e-1)" TRAV38-1 "TCRAV14S2, TCRAV38S1, TRAV381" ENSG00000211816 "T cell receptor alpha variable 38-1" A0A0B4J264 14 22271968-22272563 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 8 "lymphoid tissue: 13.0" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 31 "memory CD4 T-cell: 41.3;memory CD8 T-cell: 21.9;naive CD4 T-cell: 46.6;naive CD8 T-cell: 29.4;T-reg: 71.8" "Lineage enriched" "Detected in single" 217 "T-cells: 71.8" "Cancer enhanced" "Detected in single" "Rhabdoid: 1.0" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 65: Non-specific - Unknown function" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (4.04e-2)" "unprognostic (2.16e-2)" "unprognostic (2.03e-1)" "unprognostic (1.38e-1)" "unprognostic (5.36e-2)" TRAV38-2DV8 "hADV38S2, TCRAV14S1, TRAV38-2/DV8, TRAV382DV8" ENSG00000211817 "T cell receptor alpha variable 38-2/delta variable 8" A0JD32 14 22281105-22281748 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 11 "lymphoid tissue: 31.9" "Cell type enriched" "Detected in single" 5 "pDCs: 3.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "midbrain: 2.5" "Group enriched" "Detected in many" 5 "memory CD4 T-cell: 183.6;memory CD8 T-cell: 113.4;naive CD4 T-cell: 153.3;naive CD8 T-cell: 96.9;T-reg: 228.3" "Lineage enriched" "Detected in many" 9 "T-cells: 228.3" "Group enriched" "Detected in some" 7 "head and neck cancer: 4.9;Rhabdoid: 8.2" "Spleen - T-cells" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 80: Thymus - Adaptive immune response" "Cluster 1: Neurons - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" "unprognostic (1.45e-3)" "unprognostic (2.05e-2)" "unprognostic (9.69e-2)" "potential prognostic favorable (7.24e-5)" "unprognostic (2.73e-1)" "unprognostic (1.15e-1)" "unprognostic (3.21e-3)" "unprognostic (4.51e-3)" "unprognostic (2.97e-1)" "unprognostic (4.25e-2)" "unprognostic (7.07e-2)" "unprognostic (1.07e-1)" "unprognostic (5.95e-2)" TRAV39 "TCRAV27S1, TCRAV39S1" ENSG00000211818 "T cell receptor alpha variable 39" A0A0B4J263 14 22304054-22304553 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 12 "lymphoid tissue: 60.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 6 "memory CD4 T-cell: 33.4;memory CD8 T-cell: 27.2;naive CD4 T-cell: 35.9;naive CD8 T-cell: 23.7;T-reg: 36.8" "Lineage enriched" "Detected in many" 7 "T-cells: 36.8" "Group enriched" "Detected in some" 5 "Bile duct cancer: 2.3;head and neck cancer: 3.3;Rhabdoid: 8.9" "Not detected" "Not detected" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 80: Thymus - Adaptive immune response" "Cluster 29: Forebrain - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (8.28e-2)" "unprognostic (2.19e-1)" "unprognostic (1.03e-3)" "potential prognostic unfavorable (1.47e-4)" "unprognostic (1.03e-2)" TRAV4 "TCRAV20S1, TCRAV4S1" ENSG00000211778 "T cell receptor alpha variable 4" A0A0B4J268 14 21736152-21736982 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "lymphoid tissue: 35.2" "Group enriched" "Detected in some" 7 "pDCs: 1.9;T-cells: 5.4" "Cell type enriched" "Detected in single" 30 "leukocyte: 3.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 70 "MAIT T-cell: 66.3;memory CD4 T-cell: 82.2;memory CD8 T-cell: 124.1;naive CD4 T-cell: 77.4;naive CD8 T-cell: 81.3;T-reg: 168.5" "Lineage enriched" "Detected in many" 118 "T-cells: 168.5" "Group enriched" "Detected in some" 50 "Bone cancer: 2.0;Leukemia: 7.9" "Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells, Minor Salivary Gland - T-cells, Prostate - T-cells, Spleen - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (5.89e-2)" "unprognostic (2.15e-2)" "unprognostic (4.76e-3)" "unprognostic (7.59e-2)" "potential prognostic favorable (4.67e-4)" "unprognostic (2.97e-1)" "unprognostic (5.16e-2)" "unprognostic (4.69e-2)" "unprognostic (1.22e-1)" "unprognostic (8.26e-2)" "unprognostic (1.98e-1)" "unprognostic (5.91e-2)" "unprognostic (2.98e-1)" "unprognostic (3.74e-3)" "unprognostic (1.58e-1)" "unprognostic (8.79e-2)" "unprognostic (2.93e-1)" TRAV40 "TCRAV31S1, TCRAV40S1" ENSG00000211819 "T cell receptor alpha variable 40" A0A0B4J280 14 22314490-22314919 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 24 "lymphoid tissue: 8.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "memory CD4 T-cell: 5.4;memory CD8 T-cell: 3.2;naive CD4 T-cell: 4.8;naive CD8 T-cell: 4.4;T-reg: 6.4" "Lineage enriched" "Detected in single" 64 "T-cells: 6.4" "Not detected" "Not detected" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 80: Thymus - Adaptive immune response" "Cluster 65: Non-specific - Unknown function" "Cluster 9: T-cells - Adaptive immunity: Regulation" TRAV41 "TCRAV19S1, TCRAV41S1" ENSG00000211820 "T cell receptor alpha variable 41" A0A0B4J266 14 22320188-22320691 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 39 "lymphoid tissue: 100.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "memory CD4 T-cell: 77.3;naive CD4 T-cell: 74.4;T-reg: 71.3" "Lineage enriched" "Detected in many" 45 "T-cells: 77.3" "Cancer enhanced" "Detected in some" "lymphoma: 3.0;Rhabdoid: 4.7" "Spleen - T-cells" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 80: Thymus - Adaptive immune response" "Cluster 34: Non-specific - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (1.44e-2)" "unprognostic (1.55e-1)" "unprognostic (1.46e-1)" "unprognostic (8.59e-3)" "unprognostic (1.98e-1)" "unprognostic (6.91e-2)" "unprognostic (1.08e-2)" "unprognostic (1.22e-2)" "unprognostic (1.95e-2)" "unprognostic (1.08e-1)" "unprognostic (5.57e-2)" "unprognostic (3.62e-2)" "unprognostic (2.20e-1)" "unprognostic (1.50e-2)" TRAV5 ENSG00000211779 "T cell receptor alpha variable 5" A0A0B4J249 14 21749178-21749705 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 4 "lymphoid tissue: 12.0" "Cell type enriched" "Detected in single" 12 "T-cells: 1.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 51 "MAIT T-cell: 24.7;memory CD4 T-cell: 49.7;memory CD8 T-cell: 77.4;naive CD4 T-cell: 40.1;naive CD8 T-cell: 74.3;T-reg: 81.7" "Lineage enriched" "Detected in many" 72 "T-cells: 81.7" "Group enriched" "Detected in some" 9 "Leukemia: 33.9;lymphoma: 10.1" "Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells, Spleen - T-cells" "Not detected" "Not detected" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (9.01e-3)" "unprognostic (9.98e-2)" "unprognostic (2.30e-1)" "unprognostic (1.04e-2)" "unprognostic (7.85e-2)" "unprognostic (1.25e-1)" "unprognostic (8.56e-2)" TRAV6 TCRAV5S1 ENSG00000211780 "T cell receptor alpha variable 6" A0A075B6T7 14 21768489-21769080 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 10.4" "Cell type enriched" "Detected in single" 20 "T-cells: 3.9" "Cell type enriched" "Detected in single" 39 "leukocyte: 3.9" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 70 "MAIT T-cell: 17.1;memory CD4 T-cell: 33.8;memory CD8 T-cell: 19.0;naive CD4 T-cell: 26.4;naive CD8 T-cell: 16.3;T-reg: 59.8" "Lineage enriched" "Detected in single" 145 "T-cells: 59.8" "Group enriched" "Detected in some" 18 "Bone cancer: 6.6;Leukemia: 1.7" "Not detected" "Not detected" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 38: Sub-cortical - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (5.50e-2)" "unprognostic (1.62e-1)" "unprognostic (2.26e-1)" "unprognostic (2.81e-1)" "unprognostic (7.62e-2)" TRAV7 ENSG00000211781 "T cell receptor alpha variable 7" A0A075B6U4 14 21782993-21783503 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 12: Bone cancer - Neuronal signaling" TRAV8-1 ENSG00000211782 "T cell receptor alpha variable 8-1" A0A0A6YYK1 14 21797287-21797886 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 11.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 43 "MAIT T-cell: 14.2;memory CD4 T-cell: 39.7;memory CD8 T-cell: 20.6;naive CD4 T-cell: 37.8;naive CD8 T-cell: 16.4;T-reg: 54.6" "Lineage enriched" "Detected in single" 77 "T-cells: 54.6" "Cancer enhanced" "Detected in single" "Leukemia: 1.0" "Adipose visceral - T-cells, Lung - T-cells" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (2.24e-1)" "unprognostic (4.64e-2)" TRAV8-2 ENSG00000211786 "T cell receptor alpha variable 8-2" A0A0B4J237 14 21846537-21847221 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 9 "lymphoid tissue: 22.4" "Cell type enhanced" "Detected in some" "Late spermatids: 1.5;T-cells: 3.8" "Cell type enriched" "Detected in single" 20 "leukocyte: 2.0" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 99 "MAIT T-cell: 59.2;memory CD4 T-cell: 143.9;memory CD8 T-cell: 81.1;naive CD4 T-cell: 143.8;naive CD8 T-cell: 80.4;T-reg: 191.1" "Lineage enriched" "Detected in many" 184 "T-cells: 191.1" "Group enriched" "Detected in some" 8 "Leukemia: 1.1;lymphoma: 3.1;Rhabdoid: 1.5" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Kidney - Podocytes, Minor Salivary Gland - T-cells, Prostate - T-cells, Spleen - T-cells, Thyroid gland - T-cells" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (1.21e-2)" "unprognostic (1.31e-1)" "unprognostic (2.10e-1)" "unprognostic (2.48e-1)" "unprognostic (4.43e-3)" "unprognostic (1.93e-1)" "unprognostic (1.90e-1)" "unprognostic (2.12e-1)" "unprognostic (1.72e-1)" "unprognostic (6.58e-2)" TRAV8-3 ENSG00000211787 "T cell receptor alpha variable 8-3" A0A0A6YYJ7 14 21852558-21853006 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 66.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebral cortex: 3.0" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 138.8;T-reg: 153.7" "Lineage enriched" "Detected in many" 47 "T-cells: 153.7" "Not detected" "Not detected" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells, Minor Salivary Gland - T-cells, Prostate - T-cells, Spleen - T-cells, Thyroid gland - T-cells" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 53: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" "potential prognostic favorable (6.13e-4)" "unprognostic (4.79e-3)" "unprognostic (1.46e-2)" "unprognostic (1.03e-3)" "unprognostic (8.13e-2)" "unprognostic (3.24e-2)" "unprognostic (3.31e-3)" "unprognostic (3.29e-1)" "unprognostic (3.31e-2)" "unprognostic (9.93e-2)" "unprognostic (3.89e-2)" "unprognostic (7.41e-2)" "potential prognostic favorable (5.72e-4)" "unprognostic (2.09e-1)" "unprognostic (6.28e-2)" TRAV8-4 ENSG00000211790 "T cell receptor alpha variable 8-4" P01737 14 21894433-21895030 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 12 "lymphoid tissue: 19.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "memory CD4 T-cell: 185.5;memory CD8 T-cell: 101.8;naive CD4 T-cell: 155.2;naive CD8 T-cell: 74.8;T-reg: 235.9" "Lineage enriched" "Detected in many" 49 "T-cells: 235.9" "Cancer enriched" "Detected in some" 6 "Leukemia: 8.9" "Adipose visceral - T-cells, Lung - T-cells, Spleen - T-cells" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" "potential prognostic favorable (3.18e-4)" "unprognostic (3.79e-2)" "potential prognostic favorable (2.58e-4)" "unprognostic (1.29e-1)" "unprognostic (1.21e-2)" "unprognostic (2.70e-2)" "unprognostic (2.00e-1)" "unprognostic (1.72e-1)" "unprognostic (2.72e-1)" "unprognostic (6.59e-2)" "unprognostic (2.07e-1)" "unprognostic (3.30e-2)" TRAV8-6 ENSG00000211795 "T cell receptor alpha variable 8-6" A0A0B4J262 14 21978459-21979120 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 12 "lymphoid tissue: 23.1" "Cell type enhanced" "Detected in single" "Early primary spermatocytes: 2.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "memory CD4 T-cell: 89.6;memory CD8 T-cell: 64.2;naive CD4 T-cell: 92.9;naive CD8 T-cell: 38.8;T-reg: 125.4" "Lineage enriched" "Detected in many" 44 "T-cells: 125.4" "Cancer enriched" "Detected in some" 5 "Rhabdoid: 14.6" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Kidney - T-cells, Lung - T-cells, Prostate - T-cells, Spleen - T-cells, Thyroid gland - T-cells" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 5: Rhabdoid - Unknown function" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (1.80e-2)" "unprognostic (3.76e-2)" "unprognostic (2.56e-1)" "unprognostic (4.67e-2)" "potential prognostic favorable (9.56e-4)" "unprognostic (4.28e-2)" "unprognostic (1.39e-1)" "unprognostic (5.41e-2)" "unprognostic (3.79e-1)" "unprognostic (2.15e-2)" TRAV8-7 ENSG00000211808 "T cell receptor alpha variable 8-7 (pseudogene)" 14 22132553-22133034 "Predicted intracellular proteins, T-cell receptor genes" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 13: Non-specific - Mixed function" TRAV9-1 ENSG00000211783 "T cell receptor alpha variable 9-1" A0A075B6T8 14 21811502-21811977 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA TRAV9-2 ENSG00000211793 "T cell receptor alpha variable 9-2" A0A087WT02 14 21941128-21941657 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 9 "lymphoid tissue: 25.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "memory CD4 T-cell: 178.9;naive CD4 T-cell: 172.9;T-reg: 352.1" "Lineage enriched" "Detected in many" 78 "T-cells: 352.1" "Not detected" "Not detected" "Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells, Spleen - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (1.10e-1)" "unprognostic (1.56e-3)" "unprognostic (2.40e-3)" "unprognostic (1.10e-1)" "potential prognostic favorable (5.50e-5)" "unprognostic (9.04e-2)" "unprognostic (2.00e-1)" "potential prognostic favorable (2.36e-4)" "unprognostic (1.16e-1)" "unprognostic (1.81e-1)" "unprognostic (2.15e-1)" "unprognostic (2.89e-1)" "unprognostic (2.20e-2)" "unprognostic (2.03e-1)" "unprognostic (1.10e-2)" TRBC1 "BV05S1J2.2, TCRBC1" ENSG00000211751 "T cell receptor beta constant 1" P01850 7 142791694-142793368 "Predicted membrane proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 28 "lymphoid tissue: 1415.2" "Group enriched" "Detected in some" 11 "Innate lymphoid cells: 165.4;NK-cells: 147.9;T-cells: 232.0" "Cell type enriched" "Detected in some" 165 "leukocyte: 170.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "T-reg: 3241.7" "Lineage enriched" "Detected in all" 9 "T-cells: 3241.7" "Cancer enriched" "Detected in some" 6 "Leukemia: 101.3" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Minor Salivary Gland - T-cells, Pancreas - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Skin - T-cells, Spleen - T-cells, Thyroid gland - T-cells" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 80: Thymus - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (1.28e-2)" "unprognostic (2.34e-3)" "unprognostic (2.46e-3)" "unprognostic (3.61e-1)" "unprognostic (5.30e-2)" "unprognostic (1.21e-2)" "potential prognostic favorable (4.91e-5)" "unprognostic (3.45e-1)" "unprognostic (4.21e-2)" "unprognostic (6.66e-2)" "unprognostic (9.30e-2)" "unprognostic (3.38e-2)" "unprognostic (3.32e-3)" "unprognostic (1.63e-1)" "unprognostic (2.11e-2)" "unprognostic (2.22e-1)" "unprognostic (4.21e-2)" "unprognostic (5.02e-2)" "unprognostic (2.26e-1)" "unprognostic (4.44e-2)" "unprognostic (2.91e-2)" "unprognostic (1.47e-2)" "unprognostic (1.23e-1)" "unprognostic (5.26e-2)" "unprognostic (1.86e-2)" "unprognostic (1.42e-3)" TRBC2 TCRBC2 ENSG00000211772 "T cell receptor beta constant 2" A0A5B9 7 142801041-142802748 "Predicted membrane proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 107.2;lymphoid tissue: 180.6" "Cell type enhanced" "Detected in some" "B-cells: 54.1;Innate lymphoid cells: 59.3;Leydig cells: 38.3;NK-cells: 89.9;Peritubular myoid cells: 44.6;T-cells: 292.6;Thymocytes: 33.9" "Cell type enriched" "Detected in some" 8 "leukocyte: 156.9" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 76.2" "Lineage enriched" "Detected in many" 7 "T-cells: 76.2" "Cancer enriched" "Detected in single" 15 "Leukemia: 11.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Minor Salivary Gland - T-cells, Pancreas - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Spleen - T-cells, Stomach - T-cells, Thyroid gland - T-cells" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (3.21e-1)" "unprognostic (4.82e-2)" "unprognostic (3.92e-2)" "unprognostic (3.31e-1)" "unprognostic (4.80e-2)" "unprognostic (9.65e-2)" "unprognostic (3.26e-3)" "unprognostic (1.07e-1)" "unprognostic (3.06e-2)" TRBD1 TCRBD1 ENSG00000282431 "T cell receptor beta diversity 1" P0DPI4 7 142786213-142786224 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA TRBJ1-1 "TCRBJ1S1, TRBJ11" ENSG00000282320 "T cell receptor beta joining 1-1" A0A0J9YXA8 7 142786880-142786927 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in many" 9 "lymphoid tissue: 73.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "T-reg: 1114.2" "Lineage enriched" "Detected in all" 18 "T-cells: 1114.2" "Cancer enriched" "Detected in some" 9 "Leukemia: 11.0" "Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells, Spleen - T-cells, Thyroid gland - T-cells" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 53: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "unprognostic (2.94e-1)" "unprognostic (8.27e-1)" "unprognostic (2.87e-1)" "unprognostic (9.61e-2)" "unprognostic (9.88e-3)" "unprognostic (8.31e-2)" "unprognostic (5.46e-2)" "unprognostic (1.08e-1)" "unprognostic (6.22e-2)" "unprognostic (2.47e-1)" "unprognostic (8.42e-2)" "unprognostic (1.64e-1)" "unprognostic (5.98e-2)" TRBJ1-2 "TCRBJ1S2, TRBJ12" ENSG00000282420 "T cell receptor beta joining 1-2" A0A0J9YX06 7 142787017-142787064 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 11 "lymphoid tissue: 94.8" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 8 "memory CD4 T-cell: 495.9;memory CD8 T-cell: 335.4;naive CD4 T-cell: 468.4;naive CD8 T-cell: 297.3;T-reg: 803.6" "Lineage enriched" "Detected in all" 90 "T-cells: 803.6" "Cancer enriched" "Detected in some" 7 "Leukemia: 17.8" "Adipose visceral - T-cells, Spleen - T-cells, Thyroid gland - T-cells" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 53: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "unprognostic (2.11e-1)" "unprognostic (1.51e-1)" "unprognostic (2.28e-1)" "unprognostic (4.28e-2)" "unprognostic (9.99e-2)" "unprognostic (1.44e-1)" "unprognostic (2.49e-1)" "unprognostic (1.37e-1)" TRBJ1-3 "TCRBJ1S3, TRBJ13" ENSG00000282133 "T cell receptor beta joining 1-3" A0A0J9YWP8 7 142787630-142787679 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in many" 12 "lymphoid tissue: 198.8" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "T-reg: 172.5" "Lineage enriched" "Detected in many" 6 "T-cells: 172.5" "Cancer enriched" "Detected in some" 6 "Leukemia: 19.6" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 53: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "unprognostic (5.03e-2)" "unprognostic (2.15e-3)" "unprognostic (2.16e-1)" "potential prognostic favorable (1.67e-4)" "unprognostic (1.74e-2)" "unprognostic (1.75e-1)" "unprognostic (7.85e-2)" "unprognostic (2.47e-1)" TRBJ1-4 "TCRBJ1S4, TRBJ14" ENSG00000281958 "T cell receptor beta joining 1-4" A0A0J9YXG5 7 142788225-142788275 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in many" 10 "lymphoid tissue: 193.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "T-reg: 294.5" "Group enriched" "Detected in many" 58 "NK-cells: 133.8;T-cells: 294.5" "Cancer enriched" "Detected in some" 5 "Leukemia: 31.5" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 23: Choroid plexus - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "unprognostic (1.17e-1)" "unprognostic (1.84e-1)" "potential prognostic favorable (2.48e-4)" "unprognostic (1.14e-2)" "unprognostic (4.55e-2)" "unprognostic (4.92e-2)" "unprognostic (5.26e-3)" "unprognostic (4.14e-2)" "unprognostic (8.93e-2)" "unprognostic (7.15e-2)" "unprognostic (9.30e-2)" "unprognostic (1.49e-1)" "unprognostic (8.87e-2)" TRBJ1-5 "TCRBJ1S5, TRBJ15" ENSG00000282173 "T cell receptor beta joining 1-5" A0A0J9YXM7 7 142788498-142788547 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in many" 11 "lymphoid tissue: 278.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 31 "gdT-cell: 858.9;MAIT T-cell: 364.8;memory CD4 T-cell: 551.0;memory CD8 T-cell: 446.5;naive CD4 T-cell: 514.2;naive CD8 T-cell: 499.7;NK-cell: 364.9;T-reg: 848.1" "Group enriched" "Detected in all" 34 "NK-cells: 364.9;T-cells: 858.9" "Cancer enriched" "Detected in some" 4 "Leukemia: 42.9" "Spleen - T-cells, Thyroid gland - T-cells" NA NA "Cluster 27: T-cells - Unknown function" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 59: Leukemia - T-cell receptor" "unprognostic (2.59e-2)" "unprognostic (3.67e-1)" "unprognostic (3.16e-2)" "unprognostic (2.42e-2)" "potential prognostic favorable (9.12e-5)" "unprognostic (1.17e-1)" "unprognostic (9.07e-2)" "unprognostic (2.67e-3)" "unprognostic (9.88e-3)" "unprognostic (1.62e-1)" "unprognostic (1.68e-1)" "unprognostic (2.77e-2)" "unprognostic (6.88e-2)" "unprognostic (1.50e-1)" "unprognostic (5.71e-2)" "unprognostic (1.61e-1)" "unprognostic (5.09e-2)" TRBJ1-6 "TCRBJ1S6, TRBJ16" ENSG00000282780 "T cell receptor beta joining 1-6" A0A0J9YWX3 7 142788988-142789040 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in many" 6 "lymphoid tissue: 184.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "T-reg: 209.7" "Lineage enriched" "Detected in many" 11 "T-cells: 209.7" "Cancer enriched" "Detected in single" 35 "Leukemia: 31.3" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 59: Leukemia - T-cell receptor" "unprognostic (4.59e-2)" "unprognostic (8.04e-2)" "unprognostic (2.39e-2)" "unprognostic (1.64e-3)" "unprognostic (1.05e-2)" "unprognostic (2.60e-1)" "unprognostic (5.13e-1)" "unprognostic (8.08e-2)" "unprognostic (1.51e-1)" "unprognostic (1.09e-1)" "unprognostic (3.66e-1)" TRBJ2-1 "TCRBJ2S1, TRBJ21" ENSG00000211764 "T cell receptor beta joining 2-1" A0A0A0MTA7 7 142796365-142796414 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "bone marrow: 25.6;lymphoid tissue: 62.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "thalamus: 19.7" "Immune cell enhanced" "Detected in all" "T-reg: 1690.7" "Lineage enriched" "Detected in all" 8 "T-cells: 1690.7" "Cancer enriched" "Detected in many" 4 "Leukemia: 82.2" "Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells, Spleen - T-cells, Thyroid gland - T-cells" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 38: Sub-cortical - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "unprognostic (3.88e-1)" "unprognostic (3.91e-2)" "unprognostic (2.04e-1)" "unprognostic (7.47e-2)" "unprognostic (1.78e-1)" "unprognostic (2.51e-3)" "unprognostic (1.97e-1)" "unprognostic (1.90e-1)" "unprognostic (5.78e-1)" "unprognostic (2.92e-1)" "unprognostic (8.91e-2)" "unprognostic (3.64e-1)" "unprognostic (1.62e-1)" "unprognostic (7.11e-2)" "unprognostic (1.38e-1)" "unprognostic (2.69e-1)" "unprognostic (6.17e-1)" "unprognostic (7.22e-2)" "unprognostic (1.08e-2)" "unprognostic (1.16e-2)" TRBJ2-2 "TCRBJ2S2, TRBJ22" ENSG00000211765 "T cell receptor beta joining 2-2" 7 142796560-142796610 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "bone marrow: 18.5;lymphoid tissue: 29.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 7 "MAIT T-cell: 521.7;memory CD4 T-cell: 336.7;memory CD8 T-cell: 332.9;naive CD4 T-cell: 389.5;naive CD8 T-cell: 325.2;T-reg: 724.2" "Lineage enriched" "Detected in all" 12 "T-cells: 724.2" "Cancer enriched" "Detected in some" 4 "Leukemia: 19.7" "Spleen - T-cells" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 38: Sub-cortical - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "unprognostic (2.21e-2)" "unprognostic (1.32e-1)" "unprognostic (1.41e-1)" "unprognostic (9.61e-2)" "unprognostic (1.28e-1)" "unprognostic (2.86e-1)" "unprognostic (7.94e-2)" "unprognostic (1.56e-1)" "unprognostic (3.26e-1)" "unprognostic (5.01e-1)" "unprognostic (4.67e-1)" TRBJ2-2P TRBJ22P ENSG00000211766 "T cell receptor beta joining 2-2P (non-functional)" 7 142796697-142796742 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "bone marrow: 16.4;intestine: 11.5;lymphoid tissue: 32.8" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 28 "gdT-cell: 1438.8;MAIT T-cell: 471.3;memory B-cell: 1305.9;memory CD4 T-cell: 570.4;memory CD8 T-cell: 549.2;naive B-cell: 1403.5;naive CD4 T-cell: 517.8;naive CD8 T-cell: 583.7;NK-cell: 993.0;T-reg: 1286.1" "Group enriched" "Detected in all" 40 "B-cells: 1403.5;NK-cells: 993.0;T-cells: 1438.8" "Group enriched" "Detected in many" 6 "Leukemia: 33.8;lymphoma: 37.1;Myeloma: 13.7" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 38: Sub-cortical - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "unprognostic (8.01e-1)" "unprognostic (1.14e-1)" "unprognostic (4.69e-1)" "unprognostic (2.31e-1)" "unprognostic (6.72e-2)" "potential prognostic favorable (1.66e-4)" "potential prognostic favorable (9.17e-4)" "unprognostic (9.61e-2)" "unprognostic (3.39e-3)" "unprognostic (1.38e-2)" "unprognostic (1.73e-1)" "unprognostic (1.62e-1)" "unprognostic (1.33e-1)" "unprognostic (5.23e-2)" "unprognostic (6.28e-1)" "unprognostic (7.49e-2)" "unprognostic (1.18e-1)" "unprognostic (5.98e-2)" "unprognostic (3.52e-2)" TRBJ2-3 "TCRBJ2S3, TRBJ23" ENSG00000211767 "T cell receptor beta joining 2-3" A0A0B4J200 7 142796847-142796895 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 82.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "thalamus: 42.8" "Group enriched" "Detected in all" 12 "gdT-cell: 1491.2;MAIT T-cell: 910.2;memory B-cell: 1213.3;memory CD4 T-cell: 1125.9;memory CD8 T-cell: 1157.0;naive B-cell: 1432.5;naive CD4 T-cell: 1108.3;naive CD8 T-cell: 1034.7;NK-cell: 937.1;T-reg: 2323.3" "Group enriched" "Detected in all" 15 "B-cells: 1432.5;NK-cells: 937.1;T-cells: 2323.3" "Group enriched" "Detected in many" 6 "Leukemia: 77.1;lymphoma: 122.5;Myeloma: 45.1" "Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells, Spleen - T-cells, Thyroid gland - T-cells" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 38: Sub-cortical - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "unprognostic (5.34e-1)" "unprognostic (2.17e-3)" "unprognostic (1.12e-1)" "unprognostic (8.93e-2)" "unprognostic (2.42e-1)" "unprognostic (2.40e-3)" "potential prognostic favorable (7.53e-4)" "unprognostic (4.20e-1)" "unprognostic (4.71e-2)" "unprognostic (1.16e-2)" "unprognostic (1.16e-1)" "unprognostic (3.07e-2)" "unprognostic (5.14e-2)" "unprognostic (3.43e-3)" "unprognostic (1.91e-1)" "unprognostic (7.06e-2)" "unprognostic (2.19e-1)" "unprognostic (2.98e-1)" "unprognostic (3.35e-1)" "unprognostic (1.89e-2)" "unprognostic (1.98e-2)" "unprognostic (1.36e-1)" "unprognostic (1.90e-1)" "unprognostic (5.09e-2)" "unprognostic (2.22e-1)" TRBJ2-4 "TCRBJ2S4, TRBJ24" ENSG00000211768 "T cell receptor beta joining 2-4" 7 142796998-142797047 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "bone marrow: 8.6;lymphoid tissue: 17.9" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 5.0" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Leukemia: 21.5;lymphoma: 16.8;Myeloma: 6.0" NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 38: Sub-cortical - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "unprognostic (5.93e-2)" "unprognostic (2.79e-1)" "unprognostic (1.81e-2)" "unprognostic (1.76e-1)" "unprognostic (1.55e-1)" "unprognostic (4.20e-1)" "unprognostic (8.48e-2)" "unprognostic (1.78e-1)" TRBJ2-5 "TCRBJ2S5, TRBJ25" ENSG00000211769 "T cell receptor beta joining 2-5" 7 142797119-142797166 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 6 "bone marrow: 2.7;intestine: 4.3;lymphoid tissue: 10.0;stomach 1: 6.2" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 5.8" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "T-reg: 1105.0" "Lineage enriched" "Detected in all" 13 "T-cells: 1105.0" "Cancer enhanced" "Detected in some" "Leukemia: 24.9;lymphoma: 8.7" "Breast - T-cells, Spleen - T-cells" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 53: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "unprognostic (6.04e-1)" "unprognostic (2.75e-1)" "unprognostic (1.23e-3)" "unprognostic (8.51e-3)" "unprognostic (3.03e-1)" "unprognostic (1.16e-1)" "unprognostic (2.70e-1)" "unprognostic (1.96e-2)" "unprognostic (1.00e-1)" "unprognostic (1.43e-1)" TRBJ2-6 "TCRBJ2S6, TRBJ26" ENSG00000211770 "T cell receptor beta joining 2-6" 7 142797239-142797291 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "intestine: 9.7;lymphoid tissue: 23.4;skeletal muscle: 7.5;stomach 1: 10.0" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Leukemia: 52.6;lymphoma: 15.2" NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 38: Sub-cortical - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "unprognostic (2.47e-1)" "unprognostic (2.40e-1)" "unprognostic (4.33e-1)" "unprognostic (8.60e-2)" "unprognostic (1.20e-1)" "unprognostic (1.35e-2)" TRBJ2-7 "TCRBJ2S7, TRBJ27" ENSG00000211771 "T cell receptor beta joining 2-7" A0A0A0MT78 7 142797456-142797502 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "bone marrow: 44.4;intestine: 33.5;lymphoid tissue: 137.8" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "MAIT T-cell: 1278.7;memory CD4 T-cell: 2394.0;memory CD8 T-cell: 2654.4;naive CD4 T-cell: 2400.3;naive CD8 T-cell: 2837.5;T-reg: 4232.8" "Lineage enriched" "Detected in all" 18 "T-cells: 4232.8" "Cancer enhanced" "Detected in many" "Leukemia: 87.0;lymphoma: 25.0" "Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells, Prostate - T-cells, Spleen - T-cells, Thyroid gland - T-cells" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 38: Sub-cortical - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "unprognostic (5.42e-1)" "unprognostic (1.75e-2)" "unprognostic (6.78e-2)" "unprognostic (1.67e-1)" "unprognostic (2.89e-2)" "unprognostic (2.43e-3)" "unprognostic (4.91e-2)" "unprognostic (7.47e-2)" "unprognostic (3.61e-1)" "unprognostic (3.88e-1)" "unprognostic (4.31e-2)" "unprognostic (1.21e-1)" "unprognostic (2.71e-2)" "unprognostic (5.52e-1)" "unprognostic (3.61e-2)" "unprognostic (4.70e-2)" "unprognostic (1.38e-2)" "unprognostic (1.54e-1)" "unprognostic (1.84e-1)" "unprognostic (1.77e-1)" "unprognostic (6.28e-2)" "unprognostic (1.80e-1)" TRBV10-1 "TCRBV10S1, TCRBV12S2, TCRBV12S2A1T, TRBV101" ENSG00000211717 "T cell receptor beta variable 10-1" A0A0K0K1A3 7 142399860-142400377 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 13 "lymphoid tissue: 4.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 9 "MAIT T-cell: 3.2;memory CD4 T-cell: 4.7;memory CD8 T-cell: 3.0;naive CD4 T-cell: 6.2;naive CD8 T-cell: 2.6;T-reg: 9.5" "Lineage enriched" "Detected in single" 18 "T-cells: 9.5" "Cancer enriched" "Detected in single" 21 "Leukemia: 2.0" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 80: Thymus - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" TRBV10-2 "TCRBV10S2, TCRBV12S3, TRBV102" ENSG00000229769 "T cell receptor beta variable 10-2" A0A0K0K1G8 7 142424965-142425465 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "memory CD4 T-cell: 11.9;memory CD8 T-cell: 33.7;naive CD4 T-cell: 10.4;naive CD8 T-cell: 9.2;T-reg: 24.6" "Lineage enriched" "Detected in single" 338 "T-cells: 33.7" "Not detected" "Not detected" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 51: Lymphoid tissue - Adaptive immune response" TRBV10-3 "TCRBV10S3, TCRBV12S1A1N2, TRBV103" ENSG00000275791 "T cell receptor beta variable 10-3" A0A0K0K1G6 7 142544212-142544685 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 31 "lymphoid tissue: 82.3" "Cell type enhanced" "Detected in single" "Late spermatids: 2.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "memory CD8 T-cell: 160.5;T-reg: 203.8" "Lineage enriched" "Detected in single" 375 "T-cells: 203.8" "Cancer enriched" "Detected in single" 8 "Leukemia: 3.4" "Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells, Prostate - T-cells, Spleen - T-cells, Thyroid gland - T-cells" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 80: Thymus - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" "unprognostic (6.92e-3)" "unprognostic (5.69e-2)" "unprognostic (4.45e-3)" "unprognostic (1.75e-1)" "unprognostic (1.86e-1)" "unprognostic (1.79e-1)" "unprognostic (5.54e-2)" "unprognostic (3.04e-2)" "unprognostic (6.45e-2)" TRBV11-1 "TCRBV11S1, TCRBV21S1, TRBV111" ENSG00000211720 "T cell receptor beta variable 11-1" A0A0K0K1C0 7 142407672-142408136 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 27 "lymphoid tissue: 13.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 19 "memory CD4 T-cell: 20.1;memory CD8 T-cell: 30.4;naive CD4 T-cell: 15.7;naive CD8 T-cell: 11.8;T-reg: 25.7" "Lineage enriched" "Detected in single" 97 "T-cells: 30.4" "Not detected" "Not detected" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 80: Thymus - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" TRBV11-3 "TCRBV11S3, TCRBV21S2A2, TRBV113" ENSG00000276597 "T cell receptor beta variable 11-3" A0A5A6 7 142554836-142555318 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 30 "lymphoid tissue: 20.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 9 "MAIT T-cell: 3.1;memory CD4 T-cell: 12.0;memory CD8 T-cell: 5.2;naive CD4 T-cell: 11.7;naive CD8 T-cell: 5.9;T-reg: 10.2" "Lineage enriched" "Detected in single" 121 "T-cells: 12.0" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 80: Thymus - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" TRBV12-3 "TCRBV12S3, TCRBV8S1, TRBV123" ENSG00000274752 "T cell receptor beta variable 12-3" P01733 7 142560423-142560931 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 25 "lymphoid tissue: 56.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "memory CD4 T-cell: 29.3;memory CD8 T-cell: 14.9;naive CD4 T-cell: 32.7;naive CD8 T-cell: 24.0;T-reg: 46.2" "Lineage enriched" "Detected in many" 11 "T-cells: 46.2" "Cancer enriched" "Detected in single" 69 "Leukemia: 27.9" "Lung - T-cells, Spleen - T-cells, Thyroid gland - T-cells" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 80: Thymus - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "potential prognostic favorable (1.62e-4)" "unprognostic (4.48e-1)" "unprognostic (2.07e-1)" "unprognostic (7.66e-3)" "unprognostic (1.06e-1)" "unprognostic (2.28e-1)" "unprognostic (2.11e-1)" "unprognostic (6.79e-3)" TRBV12-4 "TCRBV12S4, TCRBV8S2A1T, TRBV124" ENSG00000276953 "T cell receptor beta variable 12-4" A0A0B4J2E0 7 142563740-142564245 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 44 "lymphoid tissue: 102.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 32 "memory CD4 T-cell: 28.7;memory CD8 T-cell: 38.7;naive CD4 T-cell: 39.8;naive CD8 T-cell: 33.8;T-reg: 54.6" "Lineage enriched" "Detected in single" 68 "T-cells: 54.6" "Cancer enhanced" "Detected in some" "colorectal cancer: 3.0" "Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells, Spleen - T-cells" NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 80: Thymus - Adaptive immune response" "Cluster 72: Neuronal - Signal transduction" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (4.72e-2)" "unprognostic (7.94e-2)" "unprognostic (9.86e-2)" "unprognostic (5.77e-3)" "unprognostic (8.82e-2)" "unprognostic (2.67e-1)" "unprognostic (2.49e-1)" "unprognostic (6.55e-2)" TRBV12-5 "TCRBV12S5, TCRBV8S3, TRBV125" ENSG00000275158 "T cell receptor beta variable 12-5" A0A1B0GX78 7 142580917-142581427 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 73 "lymphoid tissue: 44.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "memory CD4 T-cell: 4.8;naive CD4 T-cell: 8.3;naive CD8 T-cell: 8.7;T-reg: 9.9" "Lineage enriched" "Detected in single" 99 "T-cells: 9.9" "Not detected" "Not detected" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 80: Thymus - Adaptive immune response" "Cluster 14: Myeloid leukemia - Innate immune response" TRBV13 "TCRBV13S1, TCRBV23S1A2T" ENSG00000276405 "T cell receptor beta variable 13" A0A0A6YYD4 7 142535809-142536292 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 20 "lymphoid tissue: 28.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 22 "memory CD4 T-cell: 7.9;memory CD8 T-cell: 13.3;naive CD4 T-cell: 11.5;naive CD8 T-cell: 21.1;T-reg: 20.9" "Lineage enriched" "Detected in single" 211 "T-cells: 21.1" "Cancer enriched" "Detected in some" 6 "lymphoma: 6.6" "Adipose visceral - T-cells" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 80: Thymus - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" "unprognostic (6.23e-2)" "unprognostic (4.01e-2)" TRBV14 "TCRBV14S1, TCRBV16S1A1N1" ENSG00000275743 "T cell receptor beta variable 14" A0A5B0 7 142587868-142588359 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 46 "lymphoid tissue: 42.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Group enriched" "Detected in many" 10 "memory CD4 T-cell: 20.3;memory CD8 T-cell: 24.7;naive CD4 T-cell: 21.6;naive CD8 T-cell: 19.6;T-reg: 27.2" "Lineage enriched" "Detected in single" 60 "T-cells: 27.2" "Not detected" "Not detected" NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 80: Thymus - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (2.90e-1)" "unprognostic (6.02e-2)" "unprognostic (2.43e-1)" TRBV15 "TCRBV15S1, TCRBV24S1A3T" ENSG00000276819 "T cell receptor beta variable 15" 7 142592928-142593473 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 66 "lymphoid tissue: 43.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 48 "MAIT T-cell: 22.0;memory CD4 T-cell: 14.6;memory CD8 T-cell: 21.1;naive CD4 T-cell: 18.9;naive CD8 T-cell: 12.4;T-reg: 27.8" "Lineage enriched" "Detected in single" 157 "T-cells: 27.8" "Cancer enriched" "Detected in single" 125 "Leukemia: 20.1" "Adipose visceral - T-cells, Lung - T-cells, Spleen - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 80: Thymus - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" TRBV16 "TCRBV16S1, TCRBV25S1A2PT" ENSG00000275243 "T cell receptor beta variable 16" A0A087WV62 7 142598016-142598469 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "memory CD4 T-cell: 2.6;memory CD8 T-cell: 4.3;naive CD4 T-cell: 2.3;T-reg: 5.8" "Lineage enriched" "Detected in single" 59 "T-cells: 5.8" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" TRBV17 "TCRBV17S1, TCRBV26S1P" ENSG00000277880 "T cell receptor beta variable 17 (non-functional)" A0A087X0K7 7 142601628-142602360 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" NA NA "Cluster 59: Leukemia - T-cell receptor" TRBV18 TCRBV18S1 ENSG00000276557 "T cell receptor beta variable 18" A0A087X0M5 7 142615716-142616415 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 17 "lymphoid tissue: 25.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 102.3" "Lineage enriched" "Detected in single" 313 "T-cells: 102.3" "Not detected" "Not detected" "Adipose visceral - T-cells, Colon - T-cells, Kidney - T-cells, Lung - T-cells, Spleen - T-cells" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 80: Thymus - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (2.11e-1)" "unprognostic (3.14e-1)" "unprognostic (2.17e-1)" TRBV19 "TCRBV17S1A1T, TCRBV19S1" ENSG00000211746 "T cell receptor beta variable 19" A0A075B6N1 7 142618849-142619532 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "lymphoid tissue: 49.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "memory CD4 T-cell: 51.1;memory CD8 T-cell: 40.2;naive CD4 T-cell: 71.3;naive CD8 T-cell: 53.8;T-reg: 88.7" "Lineage enriched" "Detected in single" 190 "T-cells: 88.7" "Cancer enriched" "Detected in single" 14 "Leukemia: 1.4" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells, Prostate - T-cells, Spleen - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 80: Thymus - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (2.23e-1)" "unprognostic (3.24e-2)" "unprognostic (4.27e-3)" "unprognostic (4.05e-3)" "unprognostic (2.47e-1)" "unprognostic (1.77e-2)" "unprognostic (5.94e-1)" "unprognostic (2.05e-1)" "unprognostic (1.75e-1)" "unprognostic (1.72e-1)" "unprognostic (1.12e-1)" TRBV2 "TCRBV22S1A2N1T, TCRBV2S1" ENSG00000226660 "T cell receptor beta variable 2" A0A1B0GX68 7 142300924-142301432 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 22 "lymphoid tissue: 83.0" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 14 "memory CD4 T-cell: 120.8;memory CD8 T-cell: 64.5;naive CD4 T-cell: 71.8;naive CD8 T-cell: 44.7;T-reg: 123.1" "Lineage enriched" "Detected in many" 21 "T-cells: 123.1" "Cancer enriched" "Detected in single" 19 "lymphoma: 2.1" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells, Prostate - T-cells, Spleen - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 80: Thymus - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (7.75e-3)" "potential prognostic favorable (6.09e-4)" "unprognostic (5.01e-2)" "potential prognostic favorable (4.02e-4)" "unprognostic (1.50e-1)" "unprognostic (2.40e-1)" "unprognostic (4.85e-3)" "unprognostic (1.61e-1)" "unprognostic (1.13e-1)" "unprognostic (9.50e-3)" "unprognostic (2.23e-2)" "unprognostic (5.24e-3)" "unprognostic (1.67e-1)" "unprognostic (4.79e-2)" TRBV20-1 "TCRBV20S1, TCRBV2S1, TRBV201" ENSG00000211747 "T cell receptor beta variable 20-1" A0A075B6N2 7 142626649-142627399 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 27 "lymphoid tissue: 150.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "pons: 3.5" "Immune cell enhanced" "Detected in many" "T-reg: 355.4" "Lineage enriched" "Detected in many" 115 "T-cells: 355.4" "Cancer enriched" "Detected in some" 79 "Leukemia: 257.8" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Lung - T-cells, Minor Salivary Gland - T-cells, Pituitary gland - Gonadotropes, Prostate - T-cells, Spleen - T-cells, Thyroid gland - T-cells" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 80: Thymus - Adaptive immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (3.62e-1)" "unprognostic (1.32e-2)" "unprognostic (2.40e-2)" "unprognostic (2.88e-1)" "unprognostic (3.64e-1)" "unprognostic (8.68e-3)" "unprognostic (5.52e-2)" "unprognostic (1.05e-1)" "unprognostic (5.38e-2)" "unprognostic (1.06e-3)" "unprognostic (2.01e-1)" "unprognostic (3.26e-1)" "unprognostic (7.23e-2)" "unprognostic (2.34e-2)" "unprognostic (2.31e-1)" "unprognostic (2.75e-3)" "unprognostic (7.87e-2)" "unprognostic (4.71e-3)" "unprognostic (1.51e-1)" "unprognostic (1.42e-1)" "unprognostic (4.45e-1)" "unprognostic (2.73e-1)" TRBV20OR9-2 "TCRBV20S2, TCRBV2O, TCRBV2S2O, TRBV20/OR9-2" ENSG00000205274 "T cell receptor beta variable 20/OR9-2 (non-functional)" 9 33617845-33618508 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 3.7;pituitary gland: 2.7;placenta: 2.2" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Testicular Germ Cell Tumor (TCGA): 1.5" "Region enhanced" "Detected in many" "pons: 23.9" "Group enriched" "Detected in many" 16 "MAIT T-cell: 9.0;memory CD4 T-cell: 9.8;memory CD8 T-cell: 6.3;naive CD4 T-cell: 9.1;naive CD8 T-cell: 6.8;T-reg: 23.4" "Lineage enriched" "Detected in single" 36 "T-cells: 23.4" "Cancer enriched" "Detected in some" 43 "Sarcoma: 48.0" "Pituitary gland - Gonadotropes" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 71: Cerebellum - Nervous system development" "Cluster 49: Hindbrain - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 63: Cytotrophoblasts - Basic cellular functions" "unprognostic (3.08e-1)" TRBV23-1 "TCRBV19S1P, TCRBV23S1, TRBV231" ENSG00000211749 "T cell receptor beta variable 23-1 (non-functional)" A0A0A0MS06 7 142645961-142646467 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 10.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in single" "Lineage enriched" "Detected in single" 9 "T-cells: 1.0" "Not detected" "Not detected" "Adipose visceral - T-cells, Prostate - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (3.34e-2)" "unprognostic (2.28e-1)" TRBV24-1 "TCRBV15S1, TCRBV24S1, TRBV241" ENSG00000211750 "T cell receptor beta variable 24-1" A0A075B6N3 7 142656701-142657213 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 4 "lymphoid tissue: 6.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in some" 5 "basal ganglia: 5.7" "Immune cell enhanced" "Detected in many" "naive CD8 T-cell: 26.8" "Lineage enriched" "Detected in single" 129 "T-cells: 26.8" "Not detected" "Not detected" "Adipose visceral - T-cells, Skeletal muscle - Skeletal myocytes, Thyroid gland - T-cells" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 80: Thymus - Adaptive immune response" "Cluster 33: Neurons - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 9: T-cells - Adaptive immunity: Regulation" TRBV25-1 "TCRBV11S1A1T, TCRBV25S1, TRBV251" ENSG00000282499 "T cell receptor beta variable 25-1" A0A075B6N4 7 142670740-142671244 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 8 "lymphoid tissue: 23.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in some" 6 "basal ganglia: 9.5" "Group enriched" "Detected in many" 51 "MAIT T-cell: 8.3;memory CD4 T-cell: 8.7;memory CD8 T-cell: 13.4;naive CD4 T-cell: 12.4;naive CD8 T-cell: 12.2;T-reg: 25.9" "Lineage enriched" "Detected in single" 105 "T-cells: 25.9" "Not detected" "Not detected" "Adipose visceral - T-cells, Breast - T-cells, Skeletal muscle - Skeletal myocytes, Thyroid gland - T-cells" "Low region specificity" "Detected in single" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 80: Thymus - Adaptive immune response" "Cluster 33: Neurons - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" TRBV27 "TCRBV14S1, TCRBV27S1" ENSG00000211752 "T cell receptor beta variable 27" A0A0K0K1C4 7 142715346-142715861 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "lymphoid tissue: 75.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 8 "memory CD4 T-cell: 61.3;memory CD8 T-cell: 112.3;naive CD4 T-cell: 48.4;naive CD8 T-cell: 76.0;T-reg: 95.1" "Lineage enriched" "Detected in single" 135 "T-cells: 112.3" "Cancer enriched" "Detected in single" 6 "Leukemia: 3.8" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Liver - T-cells, Lung - T-cells, Prostate - T-cells, Spleen - T-cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - T-cells" "Not detected" "Not detected" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 80: Thymus - Adaptive immune response" "Cluster 33: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (1.41e-1)" "unprognostic (3.11e-3)" "unprognostic (2.97e-2)" "unprognostic (1.89e-3)" "unprognostic (3.10e-3)" "unprognostic (6.81e-2)" "unprognostic (1.25e-2)" "unprognostic (3.43e-1)" "unprognostic (5.90e-2)" "unprognostic (1.27e-1)" "unprognostic (3.75e-2)" "potential prognostic favorable (4.96e-4)" "unprognostic (3.47e-1)" "unprognostic (5.05e-2)" TRBV28 "TCRBV28S1, TCRBV3S1" ENSG00000211753 "T cell receptor beta variable 28" A0A5B6 7 142720660-142721160 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 38 "lymphoid tissue: 185.2" "Cell type enhanced" "Detected in some" "Hematopoietic stem cells: 1.9;T-cells: 4.8;Thymocytes: 1.7" "Cell type enriched" "Detected in single" 49 "leukocyte: 4.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 155.2" "Lineage enriched" "Detected in many" 78 "T-cells: 155.2" "Cancer enriched" "Detected in single" 9 "Leukemia: 2.7" "Adipose visceral - T-cells, Breast - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 80: Thymus - Adaptive immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (1.21e-1)" "unprognostic (6.97e-3)" "unprognostic (1.74e-3)" "unprognostic (3.25e-1)" "unprognostic (1.33e-1)" "unprognostic (9.18e-2)" "unprognostic (2.62e-3)" "unprognostic (2.54e-2)" "unprognostic (5.97e-2)" "unprognostic (8.23e-2)" "unprognostic (3.66e-2)" "unprognostic (2.56e-1)" "unprognostic (7.14e-2)" "unprognostic (1.69e-1)" "unprognostic (1.50e-2)" "unprognostic (3.62e-1)" "unprognostic (3.96e-2)" "unprognostic (8.38e-2)" "unprognostic (1.79e-1)" "unprognostic (2.79e-2)" TRBV29-1 "TCRBV29S1, TCRBV4S1A1T, TRBV291" ENSG00000232869 "T cell receptor beta variable 29-1" A0A5B7 7 142740206-142740894 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 91.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 44 "MAIT T-cell: 45.2;memory CD4 T-cell: 129.0;memory CD8 T-cell: 83.2;naive CD4 T-cell: 138.4;naive CD8 T-cell: 111.1;T-reg: 178.9" "Lineage enriched" "Detected in many" 68 "T-cells: 178.9" "Cancer enriched" "Detected in single" 11 "Myeloma: 1.4" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells, Prostate - T-cells, Spleen - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 80: Thymus - Adaptive immune response" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (2.30e-1)" "potential prognostic favorable (8.46e-4)" "unprognostic (1.09e-3)" "unprognostic (1.90e-1)" "potential prognostic favorable (1.14e-4)" "unprognostic (2.36e-1)" "unprognostic (3.70e-1)" "unprognostic (3.05e-2)" "unprognostic (2.39e-1)" "unprognostic (2.25e-1)" "unprognostic (1.46e-1)" "unprognostic (9.81e-2)" "unprognostic (4.63e-2)" "unprognostic (2.36e-1)" "unprognostic (3.40e-2)" TRBV3-1 "TCRBV3S1, TCRBV9S1A1T, TRBV31" ENSG00000237702 "T cell receptor beta variable 3-1" A0A576 7 142308542-142309048 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 22 "lymphoid tissue: 47.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "memory CD4 T-cell: 52.7;memory CD8 T-cell: 45.9;naive CD4 T-cell: 71.8;naive CD8 T-cell: 117.7;T-reg: 99.9" "Lineage enriched" "Detected in many" 32 "T-cells: 117.7" "Not detected" "Not detected" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells, Spleen - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 80: Thymus - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" "potential prognostic favorable (1.70e-4)" "unprognostic (1.26e-2)" "unprognostic (8.80e-2)" "unprognostic (4.83e-1)" "unprognostic (1.12e-3)" "unprognostic (1.63e-2)" "unprognostic (2.72e-1)" "unprognostic (7.43e-2)" "potential prognostic unfavorable (7.21e-4)" TRBV30 "TCRBV20S1A1N2, TCRBV30S1" ENSG00000237254 "T cell receptor beta variable 30" A0A0K0K1B3 7 142812586-142813399 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 10 "lymphoid tissue: 23.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "T-reg: 162.9" "Lineage enriched" "Detected in many" 49 "T-cells: 162.9" "Cancer enhanced" "Detected in some" "Leukemia: 7.3" "Lung - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 33: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (4.95e-1)" "unprognostic (4.41e-3)" "unprognostic (1.73e-1)" "unprognostic (6.94e-2)" "unprognostic (2.79e-1)" "unprognostic (2.72e-2)" "unprognostic (4.52e-1)" "unprognostic (7.69e-2)" "unprognostic (5.27e-2)" "unprognostic (1.92e-1)" "unprognostic (1.94e-2)" "unprognostic (4.19e-1)" TRBV4-1 "BV07S1J2.7, TCRBV4S1, TCRBV7S1A1N2T, TRBV41" ENSG00000211710 "T cell receptor beta variable 4-1" A0A577 7 142313184-142313666 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 26 "lymphoid tissue: 106.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 177.3" "Lineage enriched" "Detected in many" 89 "T-cells: 177.3" "Cancer enriched" "Detected in single" 55 "lymphoma: 8.6" "Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells, Thyroid gland - T-cells" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 80: Thymus - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (1.18e-1)" "potential prognostic favorable (1.39e-4)" "unprognostic (5.46e-2)" "unprognostic (3.07e-1)" "unprognostic (7.29e-3)" "unprognostic (3.96e-1)" "unprognostic (1.79e-1)" "unprognostic (6.43e-3)" "unprognostic (5.03e-2)" "unprognostic (1.68e-1)" "unprognostic (1.57e-1)" "unprognostic (6.77e-2)" "unprognostic (3.12e-2)" "unprognostic (1.77e-1)" "unprognostic (2.01e-2)" "unprognostic (6.92e-2)" TRBV4-2 "TCRBV4S2, TCRBV7S3A2T, TRBV42" ENSG00000211745 "T cell receptor beta variable 4-2" A0A539 7 142345421-142345985 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "lymphoid tissue: 19.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 100.5" "Lineage enriched" "Detected in single" 293 "T-cells: 100.5" "Cancer enriched" "Detected in single" 235 "Leukemia: 28.8" "Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells, Spleen - T-cells, Thyroid gland - T-cells" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 80: Thymus - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "unprognostic (6.56e-2)" TRBV5-1 "TCRBV5S1, TCRBV5S1A1T, TRBV51" ENSG00000211734 "T cell receptor beta variable 5-1" A0A578 7 142320677-142321544 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "lymphoid tissue: 41.0" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 212.3;T-reg: 296.4" "Lineage enriched" "Detected in many" 111 "T-cells: 296.4" "Not detected" "Not detected" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Lung - T-cells, Prostate - T-cells, Spleen - T-cells, Testis - Late spermatids, Thyroid gland - T-cells" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 80: Thymus - Adaptive immune response" "Cluster 11: Neuronal - Sensory perception" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (3.60e-4)" "unprognostic (9.60e-2)" "unprognostic (2.86e-2)" "unprognostic (1.25e-3)" "unprognostic (2.47e-1)" "unprognostic (1.63e-1)" "unprognostic (4.53e-2)" TRBV5-3 "TCRBV5S3, TCRBV5S5P, TRBV53" ENSG00000211715 "T cell receptor beta variable 5-3 (non-functional)" A0A0A0MS03 7 142389202-142389668 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 27 "MAIT T-cell: 2.7" "Lineage enriched" "Detected in single" 27 "T-cells: 2.7" "Not detected" "Not detected" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 71: Lymphoma - Inflammatory response" TRBV5-4 "TCRBV5S4, TCRBV5S6A3N2T, TRBV54" ENSG00000230099 "T cell receptor beta variable 5-4" A0A0C4DH59 7 142462916-142463581 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 7 "lymphoid tissue: 20.5;pancreas: 10.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 116.1" "Lineage enriched" "Detected in many" 114 "T-cells: 116.1" "Group enriched" "Detected in some" 5 "Leukemia: 3.2;ovarian cancer: 1.1" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells, Spleen - T-cells, Thyroid gland - T-cells" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (6.58e-2)" "unprognostic (3.47e-3)" "unprognostic (7.30e-2)" "unprognostic (3.75e-2)" "unprognostic (3.17e-2)" "unprognostic (7.24e-2)" "unprognostic (5.64e-2)" "unprognostic (5.43e-3)" TRBV5-5 "TCRBV5S3A2T, TCRBV5S5, TRBV55" ENSG00000211725 "T cell receptor beta variable 5-5" A0A597 7 142482548-142483019 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 26 "lymphoid tissue: 17.3" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Uterine Corpus Endometrial Carcinoma (TCGA): 2.8" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 25 "memory CD4 T-cell: 36.9;memory CD8 T-cell: 28.0;naive CD4 T-cell: 38.8;naive CD8 T-cell: 29.1;T-reg: 42.1" "Lineage enriched" "Detected in many" 30 "T-cells: 42.1" "Cancer enriched" "Detected in single" 150 "Leukemia: 25.4" "Lung - T-cells, Thyroid gland - T-cells" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 80: Thymus - Adaptive immune response" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 59: Leukemia - T-cell receptor" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" "unprognostic (4.89e-1)" TRBV5-6 "TCRBV5S2, TCRBV5S6, TRBV56" ENSG00000211728 "T cell receptor beta variable 5-6" A0A599 7 142500028-142500534 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 19 "lymphoid tissue: 31.3" "Cell type enhanced" "Detected in single" "Early spermatids: 1.0" "Cell type enriched" "Detected in single" 28 "leukocyte: 2.8" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Group enriched" "Detected in many" 14 "memory CD4 T-cell: 40.3;memory CD8 T-cell: 22.9;naive CD4 T-cell: 36.0;naive CD8 T-cell: 45.4;T-reg: 66.3" "Lineage enriched" "Detected in many" 56 "T-cells: 66.3" "Cancer enriched" "Detected in single" 439 "Leukemia: 43.9" "Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells, Spleen - T-cells, Testis - Late spermatids, Thyroid gland - T-cells" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 80: Thymus - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" "unprognostic (6.64e-2)" "unprognostic (3.96e-1)" "unprognostic (3.10e-2)" TRBV5-7 "TCRBV5S7, TCRBV5S7P, TRBV57" ENSG00000211731 "T cell receptor beta variable 5-7 (non-functional)" A0A0A0MS05 7 142520090-142520556 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 1.1;T-reg: 1.3" "Lineage enriched" "Detected in single" 13 "T-cells: 1.3" "Not detected" "Not detected" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 59: Leukemia - T-cell receptor" TRBV6-1 "TCRBV13S3, TCRBV6S1, TRBV61" ENSG00000211706 "T cell receptor beta variable 6-1" A0A0K0K1D8 7 142328297-142328786 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 49 "lymphoid tissue: 82.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 118.2;T-reg: 74.4" "Lineage enriched" "Detected in single" 125 "T-cells: 118.2" "Not detected" "Not detected" "Adipose visceral - T-cells, Lung - T-cells, Spleen - T-cells" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 80: Thymus - Adaptive immune response" "Cluster 11: Neuronal - Sensory perception" "unprognostic (1.86e-1)" "unprognostic (2.24e-1)" "unprognostic (4.12e-2)" "unprognostic (1.19e-1)" "unprognostic (6.73e-2)" "unprognostic (9.48e-2)" "unprognostic (1.38e-2)" TRBV6-2 "TCRBV13S2A1T, TCRBV6S2, TRBV62" ENSG00000283063 "T cell receptor beta variable 6-2" "A0A0J9YXY3, P0DPF7" 7 142349152-142349664 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 7.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 92.3" "Lineage enriched" "Detected in single" 174 "T-cells: 92.3" "Not detected" "Not detected" "Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells, Prostate - T-cells, Spleen - T-cells, Thyroid gland - T-cells" NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" TRBV6-4 "TCRBV13S5, TCRBV6S4, TRBV64" ENSG00000211713 "T cell receptor beta variable 6-4" A0A1B0GX49 7 142380806-142381261 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 13 "MAIT T-cell: 231.9" "Lineage enriched" "Detected in single" 1374 "T-cells: 231.9" "Not detected" "Not detected" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 10: Ciliated cells - Ion channel activity" TRBV6-5 "TCRBV13S1, TCRBV6S5, TRBV65" ENSG00000211721 "T cell receptor beta variable 6-5" A0A0K0K1A5 7 142450947-142451448 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "lymphoid tissue: 76.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "naive CD8 T-cell: 134.3;T-reg: 138.3" "Lineage enriched" "Detected in many" 53 "T-cells: 138.3" "Cancer enriched" "Detected in single" 82 "Leukemia: 22.8" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Kidney - T-cells, Lung - T-cells, Prostate - T-cells, Spleen - T-cells, Thyroid gland - T-cells" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 80: Thymus - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "unprognostic (7.24e-3)" "potential prognostic favorable (4.85e-5)" "unprognostic (1.65e-1)" "unprognostic (5.14e-2)" "unprognostic (4.79e-3)" "unprognostic (4.38e-2)" "unprognostic (1.69e-1)" "unprognostic (2.50e-1)" "unprognostic (4.93e-2)" "unprognostic (4.56e-2)" "unprognostic (1.31e-2)" "unprognostic (4.02e-1)" TRBV6-6 "TCRBV13S6A2T, TCRBV6S6, TRBV66" ENSG00000211724 "T cell receptor beta variable 6-6" A0A0A6YYG2 7 142469537-142470013 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 13.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 81.7" "Lineage enriched" "Detected in single" 98 "T-cells: 81.7" "Cancer enriched" "Detected in single" 37 "Leukemia: 8.6" "Adipose visceral - T-cells, Kidney - T-cells, Lung - T-cells, Spleen - T-cells, Thyroid gland - T-cells" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (5.42e-2)" "unprognostic (2.36e-2)" "unprognostic (1.08e-1)" "unprognostic (3.50e-2)" "unprognostic (8.85e-3)" TRBV6-7 "TCRBV13S8P, TCRBV6S7, TRBV67" ENSG00000253188 "T cell receptor beta variable 6-7 (non-functional)" A0A0A0MS04 7 142487863-142488295 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "lymphoid tissue: 1.2;pancreas: 1.5;testis: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "naive CD4 T-cell: 1.9" "Lineage enriched" "Detected in single" 6 "T-cells: 1.9" "Not detected" "Not detected" "Testis - Early spermatids" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 8: Pancreas - Proteolysis" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 59: Leukemia - T-cell receptor" TRBV6-8 "TCRBV13S7P, TCRBV6S8, TRBV68" ENSG00000253534 "T cell receptor beta variable 6-8" A0A0A6YYG3 7 142507382-142507810 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Group enriched" "Detected in some" 21 "Early spermatids: 1.2;Late spermatids: 3.0" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in single" "naive CD4 T-cell: 1.1" "Lineage enriched" "Detected in single" 12 "T-cells: 1.1" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 33: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" TRBV7-1 "TCRBV6S7P, TCRBV7S1, TRBV71" ENSG00000211707 "T cell receptor beta variable 7-1 (non-functional)" A0A0A6YYK4 7 142332182-142332701 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 7.8" "Group enriched" "Detected in some" 15 "Early spermatids: 17.1;Late spermatids: 6.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "memory CD4 T-cell: 2.0;naive CD4 T-cell: 1.8;T-reg: 2.8" "Lineage enriched" "Detected in single" 29 "T-cells: 2.8" "Not detected" "Not detected" "Testis - Late spermatids" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 21: Testis - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" TRBV7-2 "TCRBV6S5A1N1, TCRBV7S2, TRBV72" ENSG00000282939 "T cell receptor beta variable 7-2" A0A1B0GXF2 7 142352819-142353358 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 11 "epididymis: 33.2;lymphoid tissue: 79.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in single" 6 "hypothalamus: 2.2" "Immune cell enhanced" "Detected in many" "memory CD4 T-cell: 398.9;T-reg: 572.2" "Lineage enriched" "Detected in many" 79 "T-cells: 572.2" "Cancer enriched" "Detected in single" 32 "Leukemia: 13.3" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Pituitary gland - Gonadotropes, Prostate - T-cells, Spleen - T-cells, Thyroid gland - T-cells" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (2.43e-1)" "unprognostic (1.23e-1)" "unprognostic (3.17e-3)" "unprognostic (1.51e-3)" "unprognostic (4.36e-1)" "unprognostic (1.86e-1)" "unprognostic (6.15e-1)" "unprognostic (6.55e-2)" TRBV7-3 "TCRBV6S1A1N1, TCRBV7S3, TRBV73" ENSG00000211714 "T cell receptor beta variable 7-3" A0A075B6L6 7 142384329-142384841 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 6.4;testis: 2.6" "Group enriched" "Detected in some" 41 "Early spermatids: 12.9;Late spermatids: 16.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Kidney Renal Papillary Cell Carcinoma (TCGA): 1.3" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "memory CD4 T-cell: 32.0" "Lineage enriched" "Detected in single" 48 "T-cells: 32.0" "Not detected" "Not detected" "Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells, Spleen - T-cells, Testis - Late spermatids, Thyroid gland - T-cells" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 80: Thymus - Adaptive immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" "unprognostic (2.52e-1)" TRBV7-4 "TCRBV6S8A2T, TCRBV7S4, TRBV74" ENSG00000253409 "T cell receptor beta variable 7-4" A0A1B0GX95 7 142455174-142455635 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 16 "lymphoid tissue: 23.7;pancreas: 9.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "T-reg: 2.9" "Lineage enriched" "Detected in single" 29 "T-cells: 2.9" "Cancer enriched" "Detected in single" 13 "Leukemia: 11.5" "Thyroid gland - T-cells" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 80: Thymus - Adaptive immune response" "Cluster 34: Non-specific - Mixed function" "Cluster 59: Leukemia - T-cell receptor" TRBV7-6 "TCRBV6S3A1N1T, TCRBV7S6, TRBV76" ENSG00000211727 "T cell receptor beta variable 7-6" A0A1B0GX31 7 142492132-142492673 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 32.8" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 22 "memory CD4 T-cell: 54.9;memory CD8 T-cell: 42.7;naive CD4 T-cell: 62.2;naive CD8 T-cell: 37.3;T-reg: 86.4" "Lineage enriched" "Detected in many" 51 "T-cells: 86.4" "Not detected" "Not detected" "Adipose visceral - T-cells, Lung - T-cells, Spleen - T-cells, Thyroid gland - T-cells" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 80: Thymus - Adaptive immune response" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 70: DU4475 - Unknown function" "unprognostic (2.54e-1)" "unprognostic (4.16e-2)" "potential prognostic favorable (6.07e-4)" "unprognostic (2.28e-2)" "unprognostic (1.15e-1)" "unprognostic (5.12e-2)" TRBV7-7 "TCRBV6S6A2T, TCRBV7S7, TRBV77" ENSG00000253291 "T cell receptor beta variable 7-7" A0A0K0K1E9 7 142511626-142512127 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 15 "lymphoid tissue: 7.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "memory CD4 T-cell: 7.9;memory CD8 T-cell: 2.5;naive CD4 T-cell: 7.6;naive CD8 T-cell: 3.4;T-reg: 10.1" "Lineage enriched" "Detected in single" 101 "T-cells: 10.1" "Not detected" "Not detected" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 80: Thymus - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" TRBV7-9 "TCRBV6S4A1, TCRBV7S9, TRBV79" ENSG00000278030 "T cell receptor beta variable 7-9" P04435 7 142529290-142529762 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "lymphoid tissue: 51.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 37 "memory CD4 T-cell: 48.6;memory CD8 T-cell: 81.7;naive CD4 T-cell: 67.6;naive CD8 T-cell: 73.7;T-reg: 95.3" "Lineage enriched" "Detected in many" 86 "T-cells: 95.3" "Cancer enriched" "Detected in single" 87 "Leukemia: 17.1" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells, Prostate - T-cells, Skin - T-cells, Spleen - T-cells, Thyroid gland - T-cells" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (1.48e-1)" "unprognostic (5.77e-2)" "unprognostic (3.00e-1)" "potential prognostic favorable (2.76e-4)" "unprognostic (3.68e-2)" "unprognostic (2.54e-1)" "unprognostic (1.01e-1)" "unprognostic (2.44e-1)" "unprognostic (8.61e-2)" "unprognostic (5.43e-2)" "unprognostic (1.69e-2)" "unprognostic (3.20e-1)" "unprognostic (5.03e-2)" "unprognostic (3.33e-2)" TRBV9 "TCRBV1S1A1N1, TCRBV9S1" ENSG00000211716 "T cell receptor beta variable 9" A0A0B4J1U6 7 142391891-142392412 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 8.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 8 "memory CD4 T-cell: 20.1;memory CD8 T-cell: 21.7;naive CD4 T-cell: 14.9;naive CD8 T-cell: 13.2;T-reg: 27.3" "Lineage enriched" "Detected in single" 31 "T-cells: 27.3" "Cancer enhanced" "Detected in single" "Sarcoma: 1.0" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells, Spleen - T-cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - T-cells" "Not detected" "Not detected" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 80: Thymus - Adaptive immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 9: T-cells - Adaptive immunity: Regulation" "unprognostic (3.97e-2)" "unprognostic (8.40e-2)" "unprognostic (3.36e-1)" TRDC ENSG00000211829 "T cell receptor delta constant" B7Z8K6 14 22462932-22465787 "Predicted membrane proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 15 "lymphoid tissue: 376.4" "Cell type enhanced" "Detected in some" "Innate lymphoid cells: 109.3;Lacrimal acinar cells: 39.0;NK-cells: 203.3;T-cells: 49.1;Thymocytes: 168.5" "Cell type enriched" "Detected in some" 38 "leukocyte: 39.7" "Cancer enhanced" "Detected in all" "Thyroid Carcinoma (TCGA): 66.9" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 87 "gdT-cell: 5889.0;NK-cell: 2250.7" "Group enriched" "Detected in all" 150 "NK-cells: 2250.7;T-cells: 5889.0" "Cancer enhanced" "Detected in some" "breast cancer: 16.9;Leukemia: 51.9" "Heart muscle - T-cells, Kidney - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 80: Thymus - Adaptive immune response" "Cluster 15: Non-specific - Transcription" "Cluster 70: DU4475 - Unknown function" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" "unprognostic (2.53e-1)" "potential prognostic favorable (1.25e-4)" "unprognostic (9.32e-3)" "unprognostic (3.92e-1)" "unprognostic (1.61e-1)" "unprognostic (1.85e-1)" "unprognostic (1.11e-1)" "unprognostic (1.57e-3)" "unprognostic (9.80e-2)" "unprognostic (3.87e-1)" "unprognostic (9.58e-2)" "unprognostic (2.49e-2)" "unprognostic (1.53e-1)" "potential prognostic favorable (1.28e-4)" "unprognostic (2.33e-1)" "unprognostic (5.29e-2)" "unprognostic (4.54e-1)" "unprognostic (9.86e-3)" "unprognostic (2.43e-1)" "unprognostic (2.32e-1)" "unprognostic (3.48e-1)" "unprognostic (1.31e-1)" "unprognostic (1.01e-1)" "unprognostic (1.21e-1)" "unprognostic (1.73e-1)" "unprognostic (1.43e-1)" "unprognostic (2.60e-1)" "unprognostic (1.35e-2)" "unprognostic (1.21e-1)" TRDD1 ENSG00000223997 "T cell receptor delta diversity 1" P0DPR3 14 22438547-22438554 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA TRDD2 ENSG00000237235 "T cell receptor delta diversity 2" 14 22439007-22439015 "Predicted intracellular proteins, T-cell receptor genes" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA TRDD3 ENSG00000228985 "T cell receptor delta diversity 3" 14 22449113-22449125 "Predicted intracellular proteins, T-cell receptor genes" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "unprognostic (8.03e-2)" TRDJ1 ENSG00000211825 "T cell receptor delta joining 1" A0A075B706 14 22450089-22450139 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 51.5;lymphoid tissue: 67.3" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 57.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 77 "gdT-cell: 13512.1;NK-cell: 5170.0" "Group enriched" "Detected in all" 101 "NK-cells: 5170.0;T-cells: 13512.1" "Group enriched" "Detected in some" 7 "breast cancer: 12.2;cervical cancer: 8.3;Leukemia: 16.4;lymphoma: 6.9" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 51: Neurons - Mixed function" "Cluster 70: DU4475 - Unknown function" "unprognostic (7.38e-2)" "unprognostic (5.18e-1)" "unprognostic (1.69e-2)" "unprognostic (2.34e-1)" "unprognostic (1.65e-1)" "unprognostic (1.58e-2)" "unprognostic (1.57e-2)" "unprognostic (2.25e-1)" "unprognostic (3.40e-2)" "unprognostic (1.58e-3)" "unprognostic (2.05e-1)" "unprognostic (1.61e-1)" "unprognostic (4.23e-2)" "unprognostic (1.77e-1)" "unprognostic (4.76e-2)" "unprognostic (3.27e-1)" "unprognostic (1.90e-1)" "unprognostic (2.06e-1)" TRDJ2 ENSG00000211827 "T cell receptor delta joining 2" 14 22456689-22456742 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 34.0" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Thyroid Carcinoma (TCGA): 11.3;Uterine Corpus Endometrial Carcinoma (TCGA): 4.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 90 "gdT-cell: 958.5;NK-cell: 3000.7" "Group enriched" "Detected in all" 279 "NK-cells: 3000.7;T-cells: 958.5" "Group enriched" "Detected in some" 8 "breast cancer: 5.0;Leukemia: 14.6" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 34: Non-specific - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" "unprognostic (8.90e-3)" "unprognostic (2.43e-1)" "unprognostic (3.93e-1)" "unprognostic (6.51e-2)" "unprognostic (8.31e-2)" "unprognostic (2.78e-1)" "unprognostic (1.64e-2)" TRDJ3 ENSG00000211828 "T cell receptor delta joining 3" 14 22459098-22459156 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 12 "lymphoid tissue: 98.0" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 4 "gdT-cell: 2227.1" "Lineage enriched" "Detected in all" 4 "T-cells: 2227.1" "Cancer enriched" "Detected in some" 7 "Leukemia: 23.4" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 80: Thymus - Adaptive immune response" "Cluster 51: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "unprognostic (1.49e-1)" "unprognostic (1.87e-1)" "unprognostic (2.08e-1)" "unprognostic (5.58e-1)" "unprognostic (3.40e-1)" TRDJ4 ENSG00000211826 "T cell receptor delta joining 4" 14 22455249-22455296 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "intestine: 5.6;lymphoid tissue: 12.3" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 19 "Ovary Serous Cystadenocarcinoma (TCGA): 7.6" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 45 "gdT-cell: 123.3;NK-cell: 282.3" "Group enriched" "Detected in many" 362 "NK-cells: 282.3;T-cells: 123.3" "Cancer enhanced" "Detected in single" "Leukemia: 2.4" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 23: Choroid plexus - Mixed function" "Cluster 70: DU4475 - Unknown function" "unprognostic (5.64e-1)" "unprognostic (1.34e-1)" TRDMT1 "DNMT2, RNMT1" ENSG00000107614 "TRNA aspartic acid methyltransferase 1" O14717 10 17137336-17202054 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ependymal cells: 215.4;Müller glia: 114.4" "Cell type enhanced" "Detected in all" "ependymal cell: 249.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009468, HPA036945, HPA036946" Approved NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 22: Epididymis - Mixed function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 52: Non-specific - Mitochondria" "Cluster 34: Ciliated cells - Cilia assembly & function" "CAB009468: , HPA036945: , HPA036946: " "unprognostic (3.60e-3)" "unprognostic (1.11e-1)" "unprognostic (2.69e-1)" "unprognostic (6.11e-2)" "unprognostic (1.97e-1)" "unprognostic (4.92e-3)" "potential prognostic favorable (3.29e-4)" "unprognostic (7.30e-3)" "unprognostic (2.51e-2)" "unprognostic (1.17e-1)" "unprognostic (2.70e-2)" "unprognostic (1.10e-2)" "unprognostic (3.17e-2)" "unprognostic (9.82e-2)" "unprognostic (3.59e-2)" "unprognostic (2.72e-3)" "unprognostic (1.24e-1)" "unprognostic (6.46e-2)" "unprognostic (7.33e-2)" "unprognostic (2.99e-1)" "unprognostic (1.43e-1)" "unprognostic (2.44e-3)" "unprognostic (2.62e-1)" TRDN TRISK ENSG00000186439 Triadin Q13061 6 123216339-123637093 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 394.7;skeletal muscle: 1819.8;tongue: 951.2" "Group enriched" "Detected in many" 6 "Cardiomyocytes: 11282.5;Myonuclei: 8756.3;Thymic myoid cells: 3855.9" "Cell type enriched" "Detected in many" 8 "ependymal cell: 549.5" "Cancer enhanced" "Detected in some" "Head and Neck Squamous Cell Carcinoma (TCGA): 7.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 22 "Rhabdoid: 16.0" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in some" 10 "olfactory bulb: 11.0" "Region enriched" "Detected in some" 24 "olfactory bulb: 40.1" "HPA038226, HPA058226" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 39: Astrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 17 "Plasma membrane, Cytosol" Nucleoplasm "HPA038226: , HPA058226: " "unprognostic (9.96e-2)" "unprognostic (2.12e-2)" "unprognostic (1.21e-2)" "unprognostic (9.00e-2)" "unprognostic (2.63e-1)" TRDV1 hDV101S1 ENSG00000211804 "T cell receptor delta variable 1" A0A1B0GX56 14 22096032-22096619 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "lymphoid tissue: 70.0" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 7.9" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 21 "gdT-cell: 1076.1" "Lineage enriched" "Detected in many" 197 "T-cells: 1076.1" "Cancer enriched" "Detected in single" 115 "Leukemia: 11.4" "Lung - T-cells, Spleen - T-cells" NA NA "Cluster 27: T-cells - Unknown function" "Cluster 80: Thymus - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" "potential prognostic favorable (3.22e-4)" "unprognostic (2.00e-3)" "unprognostic (1.55e-1)" "unprognostic (2.48e-1)" "unprognostic (4.32e-2)" "unprognostic (3.14e-2)" "unprognostic (3.10e-2)" "unprognostic (1.06e-2)" "unprognostic (1.96e-2)" "unprognostic (1.62e-1)" "unprognostic (3.16e-1)" "unprognostic (1.20e-1)" "unprognostic (8.98e-2)" "unprognostic (5.38e-2)" TRDV2 "hDV102S1, MGC117421" ENSG00000211821 "T cell receptor delta variable 2" A0JD36 14 22422371-22423042 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 1.1;lymphoid tissue: 3.2" "Cell type enriched" "Detected in single" 6 "Thymocytes: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 219 "gdT-cell: 3231.7" "Lineage enriched" "Detected in all" 579 "T-cells: 3231.7" "Cancer enriched" "Detected in some" 6 "Rhabdoid: 28.7" "Low region specificity" "Detected in all" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 35: RS4;11 - Unknown function" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" TRDV3 hDV103S1 ENSG00000256590 "T cell receptor delta variable 3" A0JD37 14 22469041-22469698 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 18 "epididymis: 11.8;lymphoid tissue: 8.5" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 1.7;Testicular Germ Cell Tumor (TCGA): 1.3" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in some" 10 "gdT-cell: 63.6" "Lineage enriched" "Detected in single" 303 "T-cells: 63.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 11: White matter - Signal transduction" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" "unprognostic (3.50e-2)" "unprognostic (4.97e-1)" TREH "MGC129621, TRE, TREA" ENSG00000118094 Trehalase O43280 11 118657316-118679690 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 62.4" "Cell type enhanced" "Detected in many" "Adipocytes: 125.7;Early spermatids: 68.1;Enterocytes: 177.7;Epicardial cells: 268.3;Late spermatids: 763.2;Tuft cells: 184.5" "Group enriched" "Detected in some" 5 "committed oligodendrocyte precursor: 7.7;oligodendrocyte: 13.7" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 20.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA039913, HPA042045" Enhanced Uncertain Vesicles,Cytosol "Intracellular and membrane" Enzyme NA NA 3800000 "Cluster 77: Intestine - Digestion" "Cluster 11: White matter - Signal transduction" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" Cytosol Vesicles "HPA039913: , HPA042045: " "unprognostic (3.86e-1)" "validated prognostic favorable (2.22e-5)" "validated prognostic favorable (3.74e-4)" "potential prognostic favorable (1.25e-6)" "unprognostic (1.25e-3)" "unprognostic (6.24e-3)" "unprognostic (1.05e-1)" "unprognostic (3.15e-2)" "unprognostic (6.40e-2)" "unprognostic (3.08e-1)" "unprognostic (8.20e-2)" "unprognostic (2.81e-1)" TREM1 "CD354, TREM-1" ENSG00000124731 "Triggering receptor expressed on myeloid cells 1" Q9NP99 6 41267926-41286682 "CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 90.7;lung: 61.6;lymphoid tissue: 41.6" "Cell type enriched" "Detected in some" 8 "Neutrophils: 1521.3" "Cell type enriched" "Detected in some" 4 "leukocyte: 5.3" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 59.5" "Region enhanced" "Detected in many" "cerebral cortex: 16.3" "Immune cell enriched" "Detected in many" 7 "neutrophil: 616.7" "Lineage enriched" "Detected in many" 7 "granulocytes: 616.7" "Cancer enhanced" "Detected in some" "testis cancer: 5.7" "Adipose visceral - Neutrophils, Colon - Neutrophils, Spleen - Neutrophils_2, Stomach - Neutrophils, Thyroid gland - Neutrophils" "Not detected" "Not detected" "Not detected" "Not detected" "HPA005563, HPA053612" Approved Approved "Golgi apparatus" "Secreted to blood" Receptor NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 4 "Golgi apparatus" "HPA005563: , HPA053612: " "unprognostic (1.07e-1)" "unprognostic (5.10e-2)" "unprognostic (2.12e-2)" "unprognostic (3.01e-2)" "unprognostic (3.39e-1)" "unprognostic (1.49e-1)" "potential prognostic unfavorable (6.48e-4)" "unprognostic (4.71e-2)" "unprognostic (3.69e-2)" "potential prognostic unfavorable (1.01e-4)" "unprognostic (8.96e-2)" "unprognostic (2.16e-2)" "potential prognostic unfavorable (2.51e-4)" "unprognostic (4.42e-2)" "unprognostic (3.55e-2)" "unprognostic (1.33e-1)" "potential prognostic unfavorable (7.14e-4)" "unprognostic (1.27e-3)" "unprognostic (3.78e-3)" "unprognostic (2.46e-1)" "unprognostic (1.10e-3)" "unprognostic (5.53e-2)" "unprognostic (1.21e-2)" "unprognostic (1.41e-2)" "unprognostic (2.30e-1)" "unprognostic (6.43e-3)" "unprognostic (1.35e-2)" "unprognostic (1.09e-1)" "unprognostic (4.40e-2)" TREM2 "TREM-2, Trem2a, Trem2b, Trem2c" ENSG00000095970 "Triggering receptor expressed on myeloid cells 2" Q9NZC2 6 41158506-41163186 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters" Receptor "Alzheimer disease, Amyloidosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 58.6;choroid plexus: 55.1" "Cell type enriched" "Detected in some" 6 "Hofbauer cells: 979.9" "Cell type enriched" "Detected in some" 61 "central nervous system macrophage: 127.5" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 181.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 2.0" "Lineage enhanced" "Detected in single" "dendritic cells: 2.0" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.4;Leukemia: 2.6;testis cancer: 1.4" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Kidney - Macrophages, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Testis - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010917, HPA012571" Approved Uncertain Vesicles "Secreted in brain" Receptor NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 3 Vesicles "HPA010917: , HPA012571: " "unprognostic (5.16e-2)" "unprognostic (3.20e-1)" "unprognostic (1.97e-1)" "unprognostic (2.78e-3)" "unprognostic (2.62e-2)" "unprognostic (4.31e-3)" "unprognostic (1.24e-1)" "unprognostic (3.25e-1)" "unprognostic (2.27e-1)" "unprognostic (2.58e-1)" "unprognostic (2.26e-2)" "unprognostic (4.16e-2)" "unprognostic (1.08e-2)" "potential prognostic unfavorable (7.39e-4)" "unprognostic (1.17e-1)" "unprognostic (1.39e-2)" "unprognostic (6.95e-3)" "unprognostic (1.79e-1)" "unprognostic (2.52e-3)" "unprognostic (5.30e-2)" "unprognostic (2.88e-2)" "unprognostic (2.87e-2)" "unprognostic (6.56e-2)" "unprognostic (6.50e-2)" "unprognostic (3.89e-3)" "unprognostic (1.97e-2)" "unprognostic (5.52e-2)" "unprognostic (7.31e-2)" "unprognostic (2.00e-1)" "unprognostic (2.09e-3)" "unprognostic (7.42e-2)" TREML1 "dJ238O23.3, TLT1" ENSG00000161911 "Triggering receptor expressed on myeloid cells like 1" Q86YW5 6 41149337-41154347 "Plasma proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 7.7;brain: 2.7;choroid plexus: 2.2;lung: 1.9;lymphoid tissue: 6.9" "Cell type enriched" "Detected in some" 4 "Platelets: 2534.0" "Cell type enriched" "Detected in single" 42 "central nervous system macrophage: 32.8" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 3.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "basophil: 91.2" "Lineage enriched" "Detected in many" 51 "granulocytes: 91.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA016700, HPA017860" Enhanced Uncertain "Nuclear speckles,Golgi apparatus,Plasma membrane,Cytosol" NA NA 41000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 47: Platelets - Hemostasis" 4 "Nuclear speckles, Cytosol" "Golgi apparatus, Plasma membrane" "HPA016700: , HPA017860: " "unprognostic (4.47e-2)" "unprognostic (8.86e-2)" "unprognostic (3.37e-2)" "unprognostic (9.02e-3)" "unprognostic (2.16e-3)" "unprognostic (2.45e-2)" TREML2 "C6orf76, dJ238O23.1, FLJ13693, TLT2" ENSG00000112195 "Triggering receptor expressed on myeloid cells like 2" Q5T2D2 6 41189749-41201149 "Plasma proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 13.7;lymphoid tissue: 9.0" "Cell type enhanced" "Detected in some" "B-cells: 8.3;Early spermatids: 29.4;Late spermatids: 59.9;Megakaryocytes: 18.5;Neutrophil progenitors: 9.3;Neutrophils: 75.3;pDCs: 9.5;Syncytiotrophoblasts: 21.5" "Cell type enriched" "Detected in single" 10 "leukocyte: 1.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 23.3;neutrophil: 33.4" "Group enriched" "Detected in many" 15 "B-cells: 23.3;dendritic cells: 9.3;granulocytes: 33.4" "Cancer enhanced" "Detected in some" "Leukemia: 8.4;Myeloma: 13.3" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Lung - Neutrophils_2, Minor Salivary Gland - Plasma cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 890000 "Cluster 20: Non-specific - DNA binding" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 24: Neutrophils - Innate immunity signal integration" 9 "unprognostic (3.64e-3)" "unprognostic (1.43e-2)" "unprognostic (1.16e-1)" "unprognostic (2.14e-1)" "unprognostic (1.24e-1)" TREML4 TLT4 ENSG00000188056 "Triggering receptor expressed on myeloid cells like 4" Q6UXN2 6 41228339-41238882 "Predicted membrane proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "choroid plexus: 1.9" "Group enriched" "Detected in some" 5 "Choroid plexus epithelial cells: 11.7;Neutrophils: 31.6" "Cell type enriched" "Detected in single" 8 "choroid plexus epithelial cell: 5.0" "Not detected" "Not detected" "Region enhanced" "Detected in some" "choroid plexus: 3.5" "Group enriched" "Detected in some" 4 "eosinophil: 4.5;neutrophil: 8.3" "Lineage enriched" "Detected in many" 5 "granulocytes: 8.3" "Not detected" "Not detected" "Adipose visceral - Neutrophils, Colon - Neutrophils" "Not detected" "Not detected" HPA065044 Uncertain Approved "Plasma membrane" "Secreted - unknown location" Immunity NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 7: Liver cancer - Metabolism" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" "Plasma membrane" "HPA065044: " TRERF1 "BCAR2, dJ139D8.5, HSA277276, RAPA, TReP-132" ENSG00000124496 "Transcriptional regulating factor 1" Q96PN7 6 42224931-42452051 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibro-adipogenic progenitors: 265.1;Sertoli cells: 540.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Skeletal muscle - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA027771, HPA051273, HPA059943" Enhanced Enhanced "Nucleoplasm,Nucleoli fibrillar center,Cytosol" No No "Cluster 3: Non-specific - Nuclear processes" "Cluster 54: Non-specific - Ribosome" "Cluster 53: Neurons - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 14 Nucleoplasm "Nucleoli fibrillar center, Cytosol" "HPA027771: , HPA051273: , HPA059943: " "unprognostic (6.48e-2)" "unprognostic (2.25e-3)" "unprognostic (4.81e-1)" "unprognostic (1.22e-2)" "unprognostic (3.72e-1)" "unprognostic (3.05e-2)" "unprognostic (7.76e-2)" "potential prognostic favorable (5.53e-5)" "unprognostic (2.16e-3)" "unprognostic (2.35e-3)" "unprognostic (2.53e-2)" "unprognostic (3.06e-1)" "unprognostic (2.87e-2)" "unprognostic (5.57e-3)" "unprognostic (3.96e-2)" "unprognostic (9.20e-2)" "unprognostic (4.00e-1)" "unprognostic (1.04e-1)" "unprognostic (1.05e-1)" "unprognostic (7.84e-3)" "unprognostic (3.27e-2)" "unprognostic (7.51e-2)" "unprognostic (1.35e-1)" "unprognostic (1.07e-2)" "potential prognostic unfavorable (1.87e-5)" "unprognostic (1.41e-1)" "unprognostic (6.98e-2)" "unprognostic (3.63e-2)" "unprognostic (2.12e-1)" TREX1 "AGS1, DRN3" ENSG00000213689 "Three prime repair exonuclease 1" Q9NSU2 3 48465811-48467645 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Exonuclease, Hydrolase, Nuclease" "Aicardi-Goutieres syndrome, Disease variant, Neurodegeneration, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 9.9;Bergmann glia: 9.2;Brain excitatory neurons: 4.0;Brain inhibitory neurons: 2.2;Choroid plexus epithelial cells: 7.0;Ependymal cells: 8.7;Microglia: 10.2;Oligodendrocyte progenitor cells: 4.3;Oligodendrocytes: 7.5;Other brain neurons: 4.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035437, HPA046721" Supported Supported Cytosol NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 44: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 22: Non-specific - Basic cellular functions" 2 Cytosol "HPA035437: , HPA046721: " "unprognostic (8.95e-2)" "unprognostic (6.55e-2)" "unprognostic (8.50e-2)" "potential prognostic favorable (2.25e-5)" "unprognostic (7.35e-2)" "unprognostic (1.13e-1)" "unprognostic (2.35e-1)" "unprognostic (3.69e-1)" "unprognostic (1.03e-3)" "unprognostic (9.58e-2)" "unprognostic (6.12e-2)" "unprognostic (1.31e-1)" "unprognostic (4.52e-3)" "unprognostic (1.41e-1)" "unprognostic (2.33e-2)" "unprognostic (3.08e-1)" "unprognostic (1.29e-1)" "unprognostic (2.46e-2)" "unprognostic (4.37e-2)" "unprognostic (3.90e-1)" "unprognostic (1.07e-1)" "unprognostic (2.57e-1)" "unprognostic (3.49e-2)" "unprognostic (1.26e-1)" "unprognostic (9.25e-2)" "unprognostic (2.58e-2)" "unprognostic (1.55e-2)" "unprognostic (1.55e-1)" "unprognostic (1.67e-1)" "unprognostic (9.13e-2)" "unprognostic (3.46e-1)" TREX2 ENSG00000183479 "Three prime repair exonuclease 2" Q9BQ50 X 153444473-153470587 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 9.0;skin 1: 25.9" "Cell type enriched" "Detected in some" 7 "Esophageal apical cells: 91.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 6 "choroid plexus: 11.9" "Group enriched" "Detected in some" 7 "basophil: 2.1;eosinophil: 2.6" "Lineage enriched" "Detected in single" 7 "granulocytes: 2.6" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" HPA054060 Uncertain NA NA 8600 "Cluster 45: Eosinophils - Unknown function" "Cluster 9: Skin - Hair follicle development" "Cluster 23: Choroid plexus - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 84: Apical squamous epithelium - Cornification" 1 "HPA054060: " "unprognostic (2.20e-3)" "unprognostic (6.14e-2)" "potential prognostic favorable (3.91e-4)" "unprognostic (4.67e-1)" "unprognostic (2.20e-2)" "unprognostic (3.32e-1)" "unprognostic (2.91e-1)" "unprognostic (1.32e-1)" "unprognostic (2.90e-1)" "unprognostic (2.70e-1)" "unprognostic (1.39e-1)" "unprognostic (2.77e-1)" "unprognostic (1.74e-1)" "unprognostic (6.03e-2)" "unprognostic (3.96e-2)" "unprognostic (8.63e-2)" "unprognostic (6.80e-2)" TRGC1 "C1, TCRGC1" ENSG00000211689 "T cell receptor gamma constant 1" 7 38257879-38265678 "Predicted membrane proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 8 "bone marrow: 18.2;prostate: 39.3" "Cell type enhanced" "Detected in some" "Epididymal clear cells: 4.1;Innate lymphoid cells: 8.6;Monocyte progenitors: 4.6;Neutrophil progenitors: 6.2;NK-cells: 16.6;Prostatic glandular cells: 15.7;Renal collecting duct intercalated cells: 8.6;T-cells: 7.4;Thymocytes: 5.1" "Group enriched" "Detected in some" 103 "endothelial cell: 32.7;leukocyte: 75.5" "Cancer enriched" "Detected in some" 25 "Prostate Adenocarcinoma (TCGA): 369.6" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "gdT-cell: 59.7" "Group enriched" "Detected in many" 12 "NK-cells: 18.2;T-cells: 59.7" "Group enriched" "Detected in some" 10 "Leukemia: 3.6;prostate cancer: 9.3" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Lung - NK-cells (Lung), Prostate - Prostate glandular cells, Thyroid gland - T-cells" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 60: Prostate cancer - Unknown function" "Cluster 102: Non-specific - Mixed function" "unprognostic (4.13e-2)" "unprognostic (1.37e-1)" "unprognostic (1.69e-1)" "unprognostic (3.07e-1)" "unprognostic (1.04e-1)" "unprognostic (3.34e-1)" "unprognostic (1.20e-1)" "unprognostic (8.21e-2)" TRGC2 "TCRGC2, TRGC2(2X), TRGC2(3X)" ENSG00000227191 "T cell receptor gamma constant 2" 7 38239580-38249572 "Predicted membrane proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "bone marrow: 26.1;lymphoid tissue: 30.0;prostate: 21.4" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 11.7;Early spermatids: 21.6;Innate lymphoid cells: 22.2;Late spermatids: 14.2;Monocyte progenitors: 24.0;Neutrophil progenitors: 36.4;NK-cells: 54.0;Prostatic glandular cells: 15.7;T-cells: 135.7;Thymocytes: 29.6" "Group enriched" "Detected in some" 92 "endothelial cell: 42.4;leukocyte: 126.1" "Cancer enriched" "Detected in many" 17 "Prostate Adenocarcinoma (TCGA): 193.2" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "gdT-cell: 459.6" "Lineage enriched" "Detected in many" 5 "T-cells: 459.6" "Group enriched" "Detected in some" 30 "Leukemia: 41.5;prostate cancer: 10.5" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Minor Salivary Gland - T-cells, Pancreas - T-cells, Prostate - Prostate glandular cells, Skin - T-cells, Spleen - T-cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - T-cells" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 59: Leukemia - T-cell receptor" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" "unprognostic (6.51e-2)" "unprognostic (1.48e-3)" "unprognostic (4.05e-3)" "unprognostic (7.34e-2)" "unprognostic (3.37e-1)" "unprognostic (1.94e-1)" "unprognostic (1.28e-3)" "unprognostic (1.36e-1)" "unprognostic (1.14e-1)" "unprognostic (8.05e-2)" "unprognostic (1.83e-1)" "potential prognostic favorable (1.95e-4)" "unprognostic (3.23e-2)" "unprognostic (4.08e-2)" "unprognostic (3.75e-1)" "unprognostic (2.29e-2)" "unprognostic (2.13e-2)" "unprognostic (8.85e-2)" "unprognostic (1.92e-1)" "unprognostic (2.94e-1)" "unprognostic (4.77e-3)" "unprognostic (5.66e-1)" "unprognostic (2.36e-2)" "unprognostic (1.49e-1)" "unprognostic (2.21e-1)" "unprognostic (2.76e-1)" "unprognostic (4.24e-1)" TRGJ1 "J1, TCRGJ1" ENSG00000211690 "T cell receptor gamma joining 1" A0A075B6S0 7 38269491-38269540 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 16.3;lymphoid tissue: 11.6;prostate: 46.2" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 53 "Prostate Adenocarcinoma (TCGA): 30.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 254.6;MAIT T-cell: 238.0;memory CD8 T-cell: 259.5;naive CD8 T-cell: 172.1" "Lineage enriched" "Detected in many" 13 "T-cells: 259.5" "Cancer enriched" "Detected in some" 4 "prostate cancer: 23.8" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 47: Endothelial cells - Vasculature" "Cluster 59: Leukemia - T-cell receptor" "unprognostic (6.54e-2)" "unprognostic (7.51e-2)" "unprognostic (5.98e-1)" "unprognostic (9.04e-2)" "unprognostic (1.99e-1)" "unprognostic (2.97e-2)" TRGJ2 "J2, TCRGJ2" ENSG00000211687 "T cell receptor gamma joining 2" 7 38253380-38253429 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 6 "bone marrow: 16.3;lymphoid tissue: 11.6;prostate: 46.2" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 53 "Prostate Adenocarcinoma (TCGA): 30.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 254.6;MAIT T-cell: 238.0;memory CD8 T-cell: 259.5;naive CD8 T-cell: 172.1" "Lineage enriched" "Detected in many" 13 "T-cells: 259.5" "Cancer enriched" "Detected in some" 4 "prostate cancer: 23.8" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 47: Endothelial cells - Vasculature" "Cluster 59: Leukemia - T-cell receptor" "unprognostic (6.54e-2)" "unprognostic (7.51e-2)" "unprognostic (5.98e-1)" "unprognostic (9.04e-2)" "unprognostic (1.99e-1)" "unprognostic (2.97e-2)" TRGJP "JP, TCRGJP" ENSG00000211691 "T cell receptor gamma joining P" 7 38273587-38273647 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 10 "bone marrow: 25.6" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 23 "Prostate Adenocarcinoma (TCGA): 136.0" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 38 "gdT-cell: 1391.1" "Lineage enriched" "Detected in many" 38 "T-cells: 1391.1" "Not detected" "Not detected" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "unprognostic (8.18e-1)" "unprognostic (3.41e-2)" "unprognostic (5.27e-1)" TRGJP1 "JP1, TCRGJP1" ENSG00000211692 "T cell receptor gamma joining P1" 7 38276259-38276318 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 10 "bone marrow: 259.1" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 1.7" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 5 "NK-cell: 1154.6" "Lineage enriched" "Detected in many" 5 "NK-cells: 1154.6" "Cancer enriched" "Detected in some" 39 "Leukemia: 75.1" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "unprognostic (5.29e-1)" "unprognostic (9.16e-2)" "unprognostic (4.32e-1)" "unprognostic (2.62e-1)" "unprognostic (7.85e-2)" TRGJP2 "JP2, TCRGJP2" ENSG00000211688 "T cell receptor gamma joining P2" 7 38256337-38256396 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "bone marrow: 61.3;lung: 25.1;lymphoid tissue: 28.5;prostate: 30.6" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 11 "Prostate Adenocarcinoma (TCGA): 32.4" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "gdT-cell: 367.8" "Group enriched" "Detected in many" 84 "NK-cells: 187.8;T-cells: 367.8" "Cancer enriched" "Detected in some" 4 "Leukemia: 40.1" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 47: Endothelial cells - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "unprognostic (1.75e-1)" "unprognostic (2.02e-1)" "unprognostic (2.25e-1)" "unprognostic (4.06e-1)" "unprognostic (1.48e-1)" "unprognostic (3.12e-2)" "unprognostic (4.10e-2)" "unprognostic (5.19e-2)" "unprognostic (1.67e-1)" TRGV1 "TCRGV1, V1S1P" ENSG00000211701 "T cell receptor gamma variable 1 (non-functional)" A0A0A0MS02 7 38367586-38368169 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.4" "Cell type enriched" "Detected in single" 6 "Adipocytes: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 7 "Leukemia: 2.4;lymphoma: 1.2;Myeloma: 2.2" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "unprognostic (2.21e-1)" TRGV10 "TCRGV10, V3P" ENSG00000211694 "T cell receptor gamma variable 10 (non-functional)" A0A0A0MS01 7 38299811-38300322 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 13.2;lymphoid tissue: 13.1" "Group enriched" "Detected in some" 5 "Innate lymphoid cells: 3.0;NK-cells: 5.2;T-cells: 11.1" "Cell type enriched" "Detected in single" 106 "leukocyte: 19.1" "Cancer enriched" "Detected in many" 5 "Prostate Adenocarcinoma (TCGA): 14.4" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "gdT-cell: 197.2" "Lineage enriched" "Detected in many" 8 "T-cells: 197.2" "Group enriched" "Detected in some" 9 "Leukemia: 4.9;prostate cancer: 1.6" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 8: Immune cells - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" "unprognostic (2.23e-2)" "potential prognostic favorable (2.97e-4)" "unprognostic (3.40e-1)" "unprognostic (8.71e-2)" "unprognostic (2.07e-2)" "unprognostic (1.66e-1)" "unprognostic (2.61e-1)" "unprognostic (1.75e-1)" "unprognostic (2.81e-1)" "unprognostic (4.43e-1)" "unprognostic (2.56e-2)" "unprognostic (2.42e-1)" "unprognostic (5.52e-2)" TRGV11 "TCRGV11, V4P" ENSG00000211693 "T cell receptor gamma variable 11 (non-functional)" A0A075B6L2 7 38291616-38292078 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 7 "gdT-cell: 2.9" "Lineage enriched" "Detected in single" 29 "T-cells: 2.9" "Not detected" "Not detected" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 60: Prostate cancer - Unknown function" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" TRGV2 "TCRGV2, VIS2" ENSG00000233306 "T cell receptor gamma variable 2" A0A075B6R0 7 38362864-38363518 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 6.2" "Group enriched" "Detected in some" 11 "NK-cells: 1.9;T-cells: 5.7" "Cell type enriched" "Detected in single" 54 "leukocyte: 5.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "memory CD8 T-cell: 148.1" "Lineage enriched" "Detected in many" 22 "T-cells: 148.1" "Group enriched" "Detected in some" 12 "Leukemia: 3.9;lymphoma: 1.5;Myeloma: 3.4" "Adipose visceral - T-cells, Prostate - Prostate glandular cells, Thyroid gland - T-cells" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" "unprognostic (5.81e-2)" "unprognostic (3.22e-1)" "unprognostic (3.47e-1)" "unprognostic (1.91e-1)" "unprognostic (4.25e-2)" TRGV3 "TCRGV3, V1S3" ENSG00000211699 "T cell receptor gamma variable 3" P03979 7 38358512-38359162 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 11.5" "Cell type enriched" "Detected in single" 4 "T-cells: 3.4" "Cell type enriched" "Detected in single" 8 "leukocyte: 2.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "gdT-cell: 59.2" "Lineage enriched" "Detected in many" 5 "T-cells: 59.2" "Group enriched" "Detected in some" 8 "Leukemia: 12.4;lymphoma: 6.6;Myeloma: 7.8" "Adipose visceral - T-cells, Prostate - Prostate glandular cells, Thyroid gland - T-cells" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 29 "unprognostic (5.85e-2)" "unprognostic (8.33e-2)" "unprognostic (1.08e-2)" "unprognostic (2.32e-2)" "unprognostic (1.49e-2)" "unprognostic (5.40e-2)" "unprognostic (3.34e-1)" "unprognostic (9.64e-2)" "unprognostic (2.53e-1)" "unprognostic (1.64e-2)" TRGV4 "TCRGV4, V1S4" ENSG00000211698 "T cell receptor gamma variable 4" A0A0C4DH28 7 38353715-38354517 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 10.4" "Cell type enhanced" "Detected in single" "T-cells: 2.8" "Cell type enriched" "Detected in single" 49 "leukocyte: 5.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "gdT-cell: 98.1" "Lineage enriched" "Detected in many" 15 "T-cells: 98.1" "Group enriched" "Detected in some" 8 "Leukemia: 9.3;lymphoma: 4.7;Myeloma: 8.3" "Adipose visceral - T-cells" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" "unprognostic (3.52e-1)" "unprognostic (4.28e-1)" "unprognostic (4.82e-2)" "unprognostic (1.28e-1)" "unprognostic (2.63e-1)" "unprognostic (5.38e-2)" "unprognostic (1.65e-1)" "unprognostic (2.45e-1)" TRGV5 "TCRGV5, V1S5" ENSG00000211697 "T cell receptor gamma variable 5" A0A0B4J1U4 7 38349355-38350022 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 5.5" "Cell type enhanced" "Detected in some" "cDC: 1.2;Platelets: 1.4;T-cells: 3.5;Thymocytes: 1.7" "Cell type enriched" "Detected in single" 58 "leukocyte: 5.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Leukemia: 4.2;lymphoma: 5.8;Myeloma: 8.0" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" "unprognostic (1.12e-1)" "unprognostic (8.59e-3)" "unprognostic (1.56e-1)" "unprognostic (2.00e-1)" "unprognostic (1.29e-1)" "unprognostic (7.36e-2)" TRGV8 "TCRGV8, V1S8" ENSG00000211696 "T cell receptor gamma variable 8" A0A0C4DH27 7 38330343-38330935 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 6.4;prostate: 4.6" "Cell type enhanced" "Detected in some" "NK-cells: 1.4;T-cells: 3.0" "Cell type enriched" "Detected in single" 35 "leukocyte: 3.8" "Cancer enhanced" "Detected in some" "Prostate Adenocarcinoma (TCGA): 2.5" "Region enhanced" "Detected in many" "midbrain: 6.8" "Group enriched" "Detected in many" 6 "gdT-cell: 34.5;MAIT T-cell: 40.7;memory CD8 T-cell: 31.1;naive CD8 T-cell: 17.3" "Lineage enriched" "Detected in many" 7 "T-cells: 40.7" "Cancer enriched" "Detected in some" 16 "Leukemia: 20.5" "Adipose visceral - T-cells, Breast - T-cells, Prostate - Prostate glandular cells, Thyroid gland - T-cells" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" "unprognostic (3.54e-2)" "unprognostic (2.08e-1)" "unprognostic (5.92e-2)" "unprognostic (8.33e-2)" "unprognostic (2.57e-1)" "unprognostic (1.11e-1)" "unprognostic (4.13e-1)" "unprognostic (3.38e-3)" TRGV9 "TCRGV9, V2" ENSG00000211695 "T cell receptor gamma variable 9" Q99603 7 38317017-38318861 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 1.8;prostate: 5.1" "Cell type enhanced" "Detected in some" "Innate lymphoid cells: 14.3;NK-cells: 24.6;T-cells: 6.3;Thymocytes: 5.9" "Cell type enriched" "Detected in single" 30 "leukocyte: 7.1" "Cancer enriched" "Detected in single" 66 "Prostate Adenocarcinoma (TCGA): 32.1" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 13 "gdT-cell: 427.3" "Lineage enriched" "Detected in many" 13 "T-cells: 427.3" "Cancer enriched" "Detected in some" 19 "prostate cancer: 55.9" "Adipose visceral - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Prostate - Prostate glandular cells, Thyroid gland - T-cells" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 60: Prostate cancer - Unknown function" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" "unprognostic (1.52e-1)" TRH ENSG00000170893 "Thyrotropin releasing hormone" P20396 3 129974688-129977935 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 62.7;cervix: 24.5;endometrium 1: 17.6;retina: 32.7" "Cell type enriched" "Detected in some" 6 "Müller glia: 256.5" "Cell type enhanced" "Detected in some" "mammillary body: 16.7;splatter: 9.9" "Cancer enhanced" "Detected in some" "Breast Invasive Carcinoma (TCGA): 26.0;Uterine Corpus Endometrial Carcinoma (TCGA): 23.1" "Group enriched" "Detected in many" 6 "hypothalamus: 139.3;medulla oblongata: 131.2;pons: 82.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "Leukemia: 4.3" "Group enriched" "Detected in many" 5 "hypothalamus: 175.6;olfactory bulb: 148.0" "Low region specificity" "Detected in many" HPA035596 Enhanced "Secreted in other tissues" Hormone NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 11: Muller glia cells - Retinal homeostasis" 2 "HPA035596: " "unprognostic (4.63e-3)" "unprognostic (1.31e-1)" "unprognostic (6.53e-2)" "unprognostic (1.84e-1)" "unprognostic (5.30e-2)" "unprognostic (1.01e-2)" "unprognostic (1.92e-1)" "unprognostic (4.48e-2)" TRHDE "PAP-II, PGPEP2, TRH-DE" ENSG00000072657 "Thyrotropin releasing hormone degrading enzyme" Q9UKU6 12 72087266-72670758 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 11.1;pancreas: 9.8" "Cell type enhanced" "Detected in many" "Adipocytes: 1351.3;Brain excitatory neurons: 248.8;Distal convoluted tubule cells: 238.3;Leydig cells: 213.2;Loop of henle epithelial cells: 190.1;Myosatellite cells: 476.6;Pancreatic acinar cells: 471.8;Proximal tubule cells: 297.5;Renal connecting tubule cells: 366.1;Retinal ganglion cells: 247.2;Tuft cells: 276.7" "Cell type enhanced" "Detected in all" "deep-layer near-projecting: 864.7;hippocampal CA4: 1752.3" "Cancer enhanced" "Detected in some" "Kidney Chromophobe (TCGA): 7.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal medulla cells, Breast - Adipocytes (Breast), Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 4800000 "Cluster 8: Pancreas - Proteolysis" "Cluster 34: Non-specific - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 89: Adipocytes - Lipid metabolism" 7 "unprognostic (2.57e-1)" "unprognostic (8.54e-2)" "potential prognostic favorable (7.17e-8)" "unprognostic (1.04e-3)" "unprognostic (4.47e-2)" "unprognostic (2.49e-3)" "unprognostic (5.79e-2)" "unprognostic (1.77e-2)" TRHR ENSG00000174417 "Thyrotropin releasing hormone receptor" P34981 8 109086585-109121565 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Congenital hypothyroidism, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 21.6;Epicardial cells: 40.9;Lactotrophs: 14.0;Thyrotrophs: 18.2" "Cell type enhanced" "Detected in many" "amygdala excitatory: 14.0;hippocampal dentate gyrus: 30.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA055162 Approved NA NA "Cluster 29: Forebrain - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 16 "HPA055162: " TRIAP1 "HSPC132, MDM35, P53CSV, WF-1" ENSG00000170855 "TP53 regulated inhibitor of apoptosis 1" O43715 12 120443964-120446384 "Essential proteins, Predicted intracellular proteins, Transporters" "Apoptosis, Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 147.9;Esophageal basal cells: 91.3;Esophageal suprabasal cells: 96.5;Extravillous trophoblasts: 92.1;Migrating cytotrophoblasts: 161.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053640 Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 38: Non-specific - Transcription" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 14 "Nucleoplasm, Mitochondria" "HPA053640: " "unprognostic (1.95e-1)" "unprognostic (1.71e-1)" "unprognostic (2.29e-2)" "unprognostic (2.30e-1)" "unprognostic (7.48e-3)" "unprognostic (2.81e-2)" "unprognostic (2.75e-2)" "unprognostic (1.22e-1)" "unprognostic (2.37e-1)" "unprognostic (2.44e-3)" "unprognostic (2.83e-3)" "unprognostic (2.25e-1)" "unprognostic (2.23e-2)" "potential prognostic unfavorable (7.08e-4)" "unprognostic (8.46e-3)" "potential prognostic unfavorable (6.14e-4)" "unprognostic (5.84e-2)" "unprognostic (1.90e-1)" "unprognostic (1.57e-2)" "unprognostic (3.55e-2)" "unprognostic (3.93e-3)" "unprognostic (4.45e-2)" "unprognostic (4.00e-2)" "potential prognostic unfavorable (3.25e-4)" "unprognostic (4.39e-2)" "unprognostic (3.14e-2)" "potential prognostic unfavorable (3.04e-8)" "unprognostic (6.98e-2)" "unprognostic (2.76e-1)" "unprognostic (1.64e-1)" "unprognostic (1.67e-2)" TRIB1 "C8FW, GIG2, TRB1" ENSG00000173334 "Tribbles pseudokinase 1" Q96RU8 8 125430358-125438403 "Enzymes, Predicted intracellular proteins" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 345.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 332.1;Endometrial glandular cells: 280.9;Epididymal basal cells: 416.3;Neutrophils: 771.7;Ocular epithelial cells: 344.8;Plasma cells: 255.2;Urothelial cells: 255.1" "Cell type enhanced" "Detected in many" "astrocyte: 16.6;central nervous system macrophage: 30.4;pericyte: 16.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "eosinophil: 9.9;neutrophil: 4.7;non-classical monocyte: 3.5;T-reg: 2.8" "Group enriched" "Detected in many" 12 "granulocytes: 9.9;monocytes: 3.5;T-cells: 2.8" "Cancer enhanced" "Detected in all" "Myeloma: 114.7" "Kidney - Macrophages, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063982 Approved "Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 40: Non-specific - Unknown function" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 16 "Plasma membrane, Cytosol" "HPA063982: " "unprognostic (9.54e-2)" "unprognostic (1.81e-2)" "unprognostic (4.09e-3)" "unprognostic (4.13e-2)" "unprognostic (4.76e-3)" "unprognostic (2.31e-1)" "unprognostic (1.94e-1)" "unprognostic (2.75e-1)" "unprognostic (2.81e-1)" "unprognostic (5.35e-2)" "unprognostic (2.88e-1)" "unprognostic (1.04e-1)" "unprognostic (1.98e-2)" "unprognostic (8.38e-2)" "unprognostic (6.95e-2)" "unprognostic (2.67e-2)" "unprognostic (2.79e-2)" "potential prognostic unfavorable (4.85e-6)" "unprognostic (1.59e-1)" "unprognostic (1.49e-2)" "unprognostic (2.05e-1)" "unprognostic (1.24e-2)" "unprognostic (1.11e-3)" "unprognostic (6.83e-2)" "unprognostic (1.97e-1)" "unprognostic (4.74e-2)" "unprognostic (5.96e-2)" "unprognostic (1.50e-1)" "unprognostic (4.04e-2)" "unprognostic (4.26e-1)" "unprognostic (1.67e-1)" TRIB2 "GS3955, TRB2" ENSG00000071575 "Tribbles pseudokinase 2" Q92519 2 12716910-12742734 "Enzymes, Predicted membrane proteins" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bergmann glia: 229.8;Leydig cells: 101.7;Melanocytes: 129.0;Müller glia: 126.6;Parietal cells: 79.6;Peritubular myoid cells: 82.6;Podocytes: 119.8" "Cell type enhanced" "Detected in many" "Bergmann glia: 224.2;pericyte: 136.4" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 171.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 48.7" "Group enriched" "Detected in many" 8 "B-cells: 12.2;NK-cells: 19.3;T-cells: 48.7" "Cancer enhanced" "Detected in all" "Neuroblastoma: 129.2;skin cancer: 129.9" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Pituitary gland - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001305 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 2: Neurons - Nucleosome" "Cluster 69: Skin cancer - ECM organization" "Cluster 110: Mural cells - ECM organization" 11 Nucleoplasm Cytosol "HPA001305: " "unprognostic (4.98e-3)" "unprognostic (1.68e-1)" "unprognostic (1.97e-2)" "unprognostic (2.03e-2)" "unprognostic (9.13e-2)" "unprognostic (1.98e-3)" "unprognostic (4.42e-2)" "unprognostic (2.66e-2)" "unprognostic (6.89e-2)" "unprognostic (3.18e-1)" "unprognostic (2.58e-3)" "unprognostic (3.08e-3)" "unprognostic (8.29e-2)" "unprognostic (4.17e-1)" "unprognostic (7.33e-3)" "unprognostic (3.28e-1)" "unprognostic (4.71e-2)" "unprognostic (1.10e-2)" "unprognostic (3.36e-2)" "unprognostic (1.54e-1)" "unprognostic (4.43e-1)" "unprognostic (1.51e-2)" "unprognostic (1.70e-1)" "unprognostic (1.05e-1)" "unprognostic (6.88e-2)" "unprognostic (1.96e-1)" "unprognostic (1.58e-1)" "unprognostic (2.01e-1)" "unprognostic (1.97e-1)" "unprognostic (3.48e-1)" "unprognostic (6.48e-2)" TRIB3 "C20orf97, dJ1103G7.3, TRB3" ENSG00000101255 "Tribbles pseudokinase 3" Q96RU7 20 362835-397559 "Enzymes, Predicted intracellular proteins" "Apoptosis, Stress response, Transcription, Transcription regulation" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 80.6" "Cell type enhanced" "Detected in many" "Breast lactating cells: 33.0;Cholangiocytes: 23.6;Esophageal apical cells: 58.1;Hepatocytes: 27.0;Pancreatic duct cells: 33.3;Somatotrophs: 45.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA015272, HPA055442" Approved Supported Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 1: Neurons - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 86 Nucleoplasm "HPA015272: , HPA055442: " "potential prognostic unfavorable (5.17e-4)" "unprognostic (1.15e-2)" "unprognostic (3.41e-2)" "unprognostic (2.80e-1)" "unprognostic (4.03e-2)" "unprognostic (7.37e-2)" "unprognostic (1.12e-1)" "unprognostic (6.01e-2)" "potential prognostic unfavorable (2.31e-5)" "unprognostic (3.30e-2)" "potential prognostic unfavorable (1.37e-6)" "unprognostic (6.86e-3)" "potential prognostic unfavorable (2.27e-5)" "potential prognostic unfavorable (2.56e-5)" "unprognostic (1.25e-3)" "unprognostic (3.19e-3)" "unprognostic (8.16e-3)" "unprognostic (1.74e-2)" "unprognostic (7.35e-2)" "unprognostic (1.28e-1)" "unprognostic (3.73e-1)" "unprognostic (3.98e-2)" "unprognostic (5.69e-3)" "unprognostic (2.22e-1)" "unprognostic (8.75e-2)" "unprognostic (9.79e-2)" "unprognostic (2.67e-1)" "unprognostic (1.03e-1)" "unprognostic (7.80e-2)" "unprognostic (1.20e-1)" "unprognostic (1.65e-2)" TRIL KIAA0644 ENSG00000255690 "TLR4 interactor with leucine rich repeats" Q7L0X0 7 28953358-28958330 "Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 38.0" "Cell type enhanced" "Detected in many" "Astrocytes: 69.5;Bergmann glia: 62.0;Breast hormone-responsive cells: 12.1;Breast myoepithelial cells: 22.4;Ependymal cells: 62.7;Fibroblasts: 12.9;Müller glia: 18.3;Oligodendrocyte progenitor cells: 17.9" "Group enriched" "Detected in many" 4 "astrocyte: 81.9;Bergmann glia: 79.6;ependymal cell: 82.3" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 32.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 9.3;Neuroblastoma: 5.5" "Adrenal gland - Fibroblasts, Kidney - Fibroblasts, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Fibroblasts, Spleen - Fibroblasts_1, Testis - Early spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 28: Astrocytes - Homeostasis & neuron support" 1 "unprognostic (1.05e-1)" "unprognostic (1.50e-3)" "unprognostic (7.84e-2)" "unprognostic (3.15e-2)" "unprognostic (1.14e-1)" "unprognostic (2.00e-1)" "unprognostic (4.23e-3)" "unprognostic (1.38e-1)" "unprognostic (3.62e-2)" "validated prognostic favorable (3.28e-6)" "validated prognostic favorable (5.27e-4)" "unprognostic (4.27e-2)" "unprognostic (3.16e-2)" "unprognostic (2.06e-2)" "unprognostic (1.98e-1)" "unprognostic (5.97e-2)" "unprognostic (3.97e-3)" "unprognostic (4.78e-2)" "unprognostic (3.13e-3)" "unprognostic (9.56e-3)" "unprognostic (1.98e-1)" "unprognostic (3.75e-1)" "unprognostic (1.19e-2)" "unprognostic (1.70e-1)" "unprognostic (5.42e-2)" "unprognostic (2.37e-1)" "unprognostic (5.41e-2)" "unprognostic (2.61e-1)" TRIM10 "HERF1, RFB30, RNF9" ENSG00000204613 "Tripartite motif containing 10" Q9UDY6 6 30151943-30161211 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 7.4;kidney: 2.0;liver: 2.7" "Cell type enhanced" "Detected in some" "Erythrocyte progenitors: 6.0;Erythrocytes: 3.1;Platelets: 1.4;Proximal tubule cells: 4.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Kidney Renal Clear Cell Carcinoma (TCGA): 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Leukemia: 1.0" "Kidney - Proximal tubular cells, Pancreas - Ductal cells, Spleen - Erythrocytes" "Not detected" "Not detected" "Region enhanced" "Detected in some" "hippocampal formation: 3.7" HPA043325 Uncertain NA NA "Cluster 15: Bone marrow - Innate immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 7 "HPA043325: " "unprognostic (3.26e-1)" "validated prognostic favorable (1.00e-7)" "validated prognostic favorable (1.28e-4)" "unprognostic (8.15e-3)" "unprognostic (2.15e-1)" "unprognostic (2.24e-2)" TRIM11 "BIA1, RNF92" ENSG00000154370 "Tripartite motif containing 11" Q96F44 1 228393673-228406835 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 61.0" "Cell type enhanced" "Detected in many" "Early spermatids: 176.2;Esophageal apical cells: 61.1;Syncytiotrophoblasts: 73.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028541, HPA043879" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 19 "Nucleoplasm, Cytosol" "HPA028541: , HPA043879: " "unprognostic (1.67e-1)" "unprognostic (6.19e-2)" "unprognostic (5.69e-2)" "unprognostic (7.94e-3)" "unprognostic (1.08e-1)" "unprognostic (1.92e-2)" "unprognostic (2.69e-1)" "potential prognostic favorable (1.49e-5)" "unprognostic (2.86e-2)" "unprognostic (2.53e-2)" "unprognostic (6.95e-2)" "unprognostic (1.10e-1)" "unprognostic (2.89e-1)" "unprognostic (1.04e-3)" "unprognostic (5.16e-3)" "unprognostic (7.81e-2)" "unprognostic (1.34e-3)" "unprognostic (1.03e-1)" "unprognostic (1.32e-1)" "unprognostic (2.28e-1)" "unprognostic (1.95e-2)" "unprognostic (6.33e-2)" "unprognostic (1.41e-2)" "unprognostic (2.77e-2)" "unprognostic (2.42e-1)" "unprognostic (7.07e-2)" "unprognostic (1.32e-1)" "unprognostic (5.68e-2)" "unprognostic (4.88e-2)" "unprognostic (2.33e-2)" "unprognostic (1.61e-1)" TRIM13 "DLEU5, Leu5, RFP2, RNF77" ENSG00000204977 "Tripartite motif containing 13" O60858 13 49995888-50020481 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 497.5;Epicardial cells: 354.8;Late primary spermatocytes: 681.6;Myonuclei: 328.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000367 Enhanced NA NA "Cluster 24: Non-specific - Transcription" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 13 "HPA000367: " "unprognostic (1.29e-2)" "unprognostic (1.98e-1)" "unprognostic (2.11e-1)" "unprognostic (8.16e-2)" "unprognostic (1.21e-1)" "unprognostic (1.25e-1)" "unprognostic (3.35e-3)" "unprognostic (1.49e-2)" "unprognostic (2.08e-2)" "unprognostic (2.31e-1)" "validated prognostic favorable (3.43e-7)" "validated prognostic favorable (1.09e-4)" "unprognostic (1.19e-3)" "unprognostic (1.81e-1)" "unprognostic (3.35e-1)" "unprognostic (6.03e-3)" "unprognostic (1.41e-1)" "unprognostic (2.12e-1)" "unprognostic (7.77e-2)" "unprognostic (3.68e-3)" "unprognostic (1.20e-1)" "unprognostic (1.32e-1)" "unprognostic (2.15e-1)" "unprognostic (1.41e-1)" "unprognostic (3.50e-2)" "unprognostic (2.47e-1)" "unprognostic (1.66e-2)" "unprognostic (3.31e-1)" "unprognostic (2.48e-1)" "unprognostic (1.89e-1)" "unprognostic (9.33e-2)" TRIM14 KIAA0129 ENSG00000106785 "Tripartite motif containing 14" Q14142 9 98069275-98119222 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Kupffer cells: 294.1;Macrophages: 108.7;Monocyte progenitors: 108.0" "Cell type enhanced" "Detected in all" "leukocyte: 106.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Heart muscle - Macrophages, Kidney - Proximal tubular cells, Prostate - Urothelial cells, Skeletal muscle - Macrophages, Spleen - Macrophages, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA053217 Uncertain NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 38 "HPA053217: " "unprognostic (2.90e-2)" "unprognostic (2.32e-1)" "unprognostic (5.34e-2)" "unprognostic (7.60e-2)" "unprognostic (2.38e-1)" "unprognostic (3.90e-2)" "unprognostic (3.04e-1)" "unprognostic (4.04e-2)" "unprognostic (2.59e-1)" "unprognostic (1.47e-1)" "potential prognostic favorable (1.88e-4)" "unprognostic (9.78e-2)" "unprognostic (9.31e-2)" "unprognostic (1.67e-1)" "unprognostic (1.01e-1)" "unprognostic (1.63e-1)" "unprognostic (1.25e-3)" "unprognostic (2.90e-2)" "unprognostic (2.91e-1)" "unprognostic (2.12e-1)" "unprognostic (3.48e-2)" "unprognostic (3.74e-2)" "unprognostic (1.69e-1)" "unprognostic (1.09e-2)" "unprognostic (1.09e-2)" "unprognostic (4.67e-2)" "unprognostic (1.38e-1)" "unprognostic (1.87e-1)" "unprognostic (6.41e-2)" "unprognostic (4.55e-3)" "unprognostic (5.18e-2)" TRIM15 "RNF93, ZNF178, ZNFB7" ENSG00000204610 "Tripartite motif containing 15" Q9C019 6 30163206-30172693 "Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "intestine: 16.0;kidney: 6.7;liver: 16.2" "Cell type enhanced" "Detected in some" "Cholangiocytes: 2.0;Colonocytes: 1.9;Enterocytes: 1.1;Foveolar cells: 2.9;Gastric progenitor cells: 1.3;Platelets: 1.4;Proximal tubule cells: 6.9" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 15.3;Rectum Adenocarcinoma (TCGA): 12.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 3.8;colorectal cancer: 5.2;Gastric cancer: 6.5" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Pancreas - Ductal cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA047527 Approved "Centriolar satellite,Cytosol" NA NA "Cluster 77: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 18 Cytosol "Centriolar satellite" "HPA047527: " "unprognostic (5.92e-2)" "unprognostic (2.33e-1)" "unprognostic (2.86e-2)" "potential prognostic favorable (1.98e-5)" "unprognostic (2.67e-3)" "unprognostic (6.16e-2)" "unprognostic (8.11e-3)" "unprognostic (1.24e-1)" "unprognostic (5.02e-2)" "unprognostic (7.57e-2)" "unprognostic (2.39e-1)" "unprognostic (1.38e-1)" "unprognostic (8.04e-2)" TRIM16 EBBP ENSG00000221926 "Tripartite motif containing 16" O95361 17 15627960-15684311 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 141.5" "Cell type enhanced" "Detected in many" "Sertoli cells: 44.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 9 "T-reg: 44.9" "Lineage enriched" "Detected in many" 11 "T-cells: 44.9" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA023623, HPA066431" Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 7: Liver cancer - Metabolism" "Cluster 7: Non-specific - Transcription" 10 Cytosol "Plasma membrane" "HPA023623: , HPA066431: " "unprognostic (2.04e-2)" "unprognostic (2.99e-1)" "unprognostic (5.19e-2)" "unprognostic (1.07e-1)" "unprognostic (1.23e-1)" "unprognostic (2.80e-2)" "unprognostic (1.48e-1)" "potential prognostic favorable (6.82e-4)" "unprognostic (6.18e-2)" "unprognostic (6.83e-2)" "unprognostic (1.31e-3)" "potential prognostic unfavorable (2.08e-4)" "potential prognostic unfavorable (6.69e-5)" "potential prognostic unfavorable (4.12e-4)" "unprognostic (2.15e-3)" "potential prognostic unfavorable (4.61e-4)" "unprognostic (1.08e-1)" "unprognostic (2.34e-1)" "unprognostic (3.32e-1)" "unprognostic (3.81e-1)" "unprognostic (6.68e-2)" "unprognostic (1.07e-2)" "unprognostic (2.60e-1)" "unprognostic (8.53e-2)" "unprognostic (3.27e-2)" "unprognostic (4.37e-2)" "unprognostic (3.92e-2)" "unprognostic (4.08e-2)" "unprognostic (1.85e-1)" "unprognostic (5.49e-3)" "unprognostic (1.91e-1)" TRIM17 "RBCC, RNF16, terf" ENSG00000162931 "Tripartite motif containing 17" Q9Y577 1 228407935-228416861 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 45.2;testis: 39.3" "Group enriched" "Detected in some" 14 "Early spermatids: 351.4;Late primary spermatocytes: 98.4;Late spermatids: 101.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 4.8" "Lung - Respiratory ciliated cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA054908 Approved Approved Vesicles NA NA "Cluster 67: Testis - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 16 Vesicles "HPA054908: " "unprognostic (3.14e-1)" "unprognostic (3.93e-3)" "unprognostic (1.11e-1)" "unprognostic (5.63e-2)" "unprognostic (2.51e-1)" "unprognostic (3.60e-2)" "unprognostic (7.27e-2)" "unprognostic (1.96e-1)" "unprognostic (2.06e-1)" "unprognostic (8.08e-3)" "unprognostic (1.28e-1)" "unprognostic (3.76e-1)" "potential prognostic unfavorable (2.63e-5)" "unprognostic (1.86e-1)" "unprognostic (5.54e-2)" "unprognostic (1.00e-2)" "unprognostic (1.33e-1)" TRIM2 "CMT2R, KIAA0517, RNF86" ENSG00000109654 "Tripartite motif containing 2" Q9C040 4 153152163-153339319 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 62.9" "Cell type enhanced" "Detected in some" "Astrocytes: 301.8;Bergmann glia: 274.5;Brain excitatory neurons: 321.3;Brain inhibitory neurons: 223.7;Choroid plexus epithelial cells: 359.8;Distal convoluted tubule cells: 413.6;Ependymal cells: 492.3;Loop of henle epithelial cells: 370.1;Oligodendrocyte progenitor cells: 363.3;Oligodendrocytes: 1616.1;Other brain neurons: 295.8;Papillary tip epithelial cells: 170.0;Renal collecting duct intercalated cells: 509.2;Renal collecting duct principal cells: 223.1;Renal connecting tubule cells: 276.8" "Cell type enhanced" "Detected in all" "oligodendrocyte: 1944.6" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 66.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory CD4 T-cell: 1.0" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "skin cancer: 46.1" "Skeletal muscle - Fibroblasts, Spleen - Endothelial cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035853, HPA035854" Supported Uncertain Centrosome NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 80: Oligodendrocytes - Myelination" 19 Centrosome "HPA035853: , HPA035854: " "unprognostic (3.14e-2)" "unprognostic (1.82e-1)" "unprognostic (1.64e-1)" "unprognostic (9.36e-2)" "unprognostic (6.25e-2)" "unprognostic (1.58e-2)" "unprognostic (1.00e-1)" "unprognostic (4.08e-2)" "unprognostic (1.29e-1)" "unprognostic (1.02e-2)" "validated prognostic favorable (1.59e-9)" "validated prognostic favorable (1.86e-4)" "unprognostic (1.81e-2)" "unprognostic (5.27e-2)" "unprognostic (5.99e-2)" "unprognostic (1.14e-2)" "unprognostic (9.71e-3)" "unprognostic (1.51e-1)" "unprognostic (1.45e-2)" "unprognostic (5.52e-2)" "unprognostic (6.49e-3)" "unprognostic (3.28e-1)" "unprognostic (6.12e-2)" "unprognostic (2.03e-1)" "unprognostic (1.36e-3)" "unprognostic (4.22e-1)" "unprognostic (6.01e-2)" "unprognostic (1.84e-2)" "unprognostic (2.41e-1)" "unprognostic (3.71e-2)" "unprognostic (3.21e-2)" TRIM21 "RNF81, RO52, SSA1" ENSG00000132109 "Tripartite motif containing 21" P19474 11 4384897-4393702 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Host-virus interaction, Ubl conjugation pathway" "DNA-binding, Ribonucleoprotein, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 35.7" "Cell type enhanced" "Detected in many" "endothelial cell: 6.4;leukocyte: 7.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004566, HPA005673" Enhanced Approved Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 134 Nucleoplasm "CAB004566: , HPA005673: " "unprognostic (1.70e-1)" "unprognostic (1.69e-3)" "unprognostic (6.64e-3)" "unprognostic (2.57e-1)" "unprognostic (1.67e-2)" "unprognostic (3.30e-2)" "unprognostic (1.53e-1)" "unprognostic (5.73e-3)" "unprognostic (1.04e-1)" "unprognostic (1.18e-1)" "potential prognostic favorable (3.59e-5)" "unprognostic (1.35e-2)" "unprognostic (2.57e-2)" "potential prognostic unfavorable (1.19e-6)" "potential prognostic favorable (6.62e-4)" "unprognostic (1.29e-1)" "unprognostic (5.35e-3)" "unprognostic (1.01e-1)" "unprognostic (2.43e-1)" "unprognostic (2.65e-1)" "unprognostic (6.98e-2)" "unprognostic (1.36e-2)" "unprognostic (7.94e-2)" "unprognostic (2.02e-1)" "unprognostic (4.13e-2)" "unprognostic (3.52e-2)" "unprognostic (2.44e-1)" "unprognostic (2.35e-2)" "unprognostic (5.92e-2)" "potential prognostic favorable (3.75e-6)" "unprognostic (1.07e-1)" TRIM22 "GPSTAF50, RNF94, STAF50" ENSG00000132274 "Tripartite motif containing 22" Q8IYM9 11 5689610-5737089 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Transcription, Transcription regulation, Ubl conjugation pathway" "Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 190.0;Hematopoietic stem cells: 153.8;Kupffer cells: 157.8;Microglia: 187.9;Neutrophils: 222.1;NK-cells: 119.8;T-cells: 123.2" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 230.8;leukocyte: 156.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA003307, HPA003575" Approved Supported "Nucleoplasm,Nuclear bodies,Golgi apparatus" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 9: Non-specific - Receptor signaling" "Cluster 55: Lymphoma - Immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 7 "Nucleoplasm, Nuclear bodies" "Golgi apparatus" "HPA003307: , HPA003575: " "unprognostic (2.95e-3)" "unprognostic (3.41e-1)" "unprognostic (2.79e-2)" "unprognostic (2.20e-1)" "unprognostic (2.97e-1)" "unprognostic (1.05e-1)" "unprognostic (1.93e-1)" "unprognostic (2.93e-2)" "unprognostic (1.33e-1)" "unprognostic (2.97e-2)" "potential prognostic favorable (2.64e-5)" "unprognostic (1.30e-2)" "unprognostic (1.42e-1)" "unprognostic (2.18e-1)" "unprognostic (3.77e-3)" "unprognostic (1.12e-3)" "unprognostic (1.14e-2)" "unprognostic (6.02e-3)" "unprognostic (3.40e-1)" "unprognostic (1.33e-1)" "unprognostic (2.21e-1)" "unprognostic (2.24e-2)" "unprognostic (2.67e-3)" "unprognostic (1.28e-1)" "unprognostic (6.62e-2)" "unprognostic (4.33e-2)" "unprognostic (2.88e-1)" "unprognostic (6.38e-2)" "unprognostic (1.22e-1)" "unprognostic (2.40e-1)" "unprognostic (1.55e-1)" TRIM23 "ARD1, ARFD1, RNF46" ENSG00000113595 "Tripartite motif containing 23" P36406 5 65589690-65625975 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Host-virus interaction, Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039605 Approved NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 65: Brain - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 7: Non-specific - Transcription" 174 "HPA039605: " "unprognostic (3.66e-2)" "unprognostic (1.80e-1)" "unprognostic (1.55e-1)" "unprognostic (4.22e-1)" "unprognostic (3.49e-1)" "unprognostic (2.22e-1)" "unprognostic (2.49e-1)" "unprognostic (4.53e-2)" "unprognostic (6.91e-2)" "unprognostic (3.64e-2)" "potential prognostic favorable (2.27e-7)" "unprognostic (1.24e-2)" "unprognostic (4.88e-2)" "unprognostic (9.16e-2)" "unprognostic (1.90e-1)" "unprognostic (1.07e-1)" "unprognostic (2.30e-1)" "unprognostic (1.45e-1)" "unprognostic (1.70e-1)" "unprognostic (6.60e-3)" "potential prognostic unfavorable (5.86e-6)" "unprognostic (3.41e-2)" "unprognostic (2.13e-2)" "unprognostic (1.33e-1)" "unprognostic (4.72e-2)" "unprognostic (5.22e-3)" "unprognostic (1.03e-1)" "unprognostic (4.23e-2)" "unprognostic (2.58e-1)" "unprognostic (6.41e-3)" "unprognostic (1.16e-2)" TRIM24 "hTIF1, RNF82, TIF1, Tif1a" ENSG00000122779 "Tripartite motif containing 24" O15164 7 138460259-138589996 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "DNA-binding, Repressor, Transferase" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 316.4;Thymocytes: 277.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043495, HPA061717" Approved Enhanced Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 9: T-cells - Adaptive immunity: Regulation" 69 Nucleoplasm "HPA043495: , HPA061717: " "unprognostic (4.13e-1)" "unprognostic (3.32e-1)" "unprognostic (9.39e-2)" "unprognostic (2.80e-2)" "unprognostic (8.51e-2)" "unprognostic (2.08e-1)" "unprognostic (3.26e-1)" "unprognostic (3.19e-2)" "unprognostic (1.39e-1)" "unprognostic (1.15e-3)" "potential prognostic favorable (8.69e-5)" "unprognostic (1.37e-1)" "unprognostic (2.39e-1)" "potential prognostic unfavorable (5.59e-4)" "unprognostic (1.02e-2)" "unprognostic (2.12e-2)" "unprognostic (2.82e-1)" "unprognostic (4.07e-2)" "unprognostic (8.75e-2)" "unprognostic (5.09e-2)" "unprognostic (8.84e-2)" "unprognostic (1.15e-1)" "unprognostic (2.93e-1)" "unprognostic (1.26e-1)" "unprognostic (1.89e-1)" "unprognostic (1.84e-1)" "unprognostic (7.40e-2)" "unprognostic (3.71e-1)" "unprognostic (2.95e-2)" "unprognostic (3.12e-2)" "unprognostic (1.08e-2)" TRIM25 "EFP, RNF147, ZNF147" ENSG00000121060 "Tripartite motif containing 25" Q14258 17 56836387-56914080 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity, Ubl conjugation pathway" "Ligase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 181.7;Endometrial luminal cells: 259.6;monocytes: 135.4;Neutrophils: 451.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 8.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA005909 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 8100 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 49: Non-specific - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 196 "Nucleoplasm, Cytosol" "Nuclear bodies" "HPA005909: " "unprognostic (4.70e-1)" "unprognostic (1.16e-2)" "unprognostic (1.92e-2)" "potential prognostic unfavorable (3.28e-4)" "unprognostic (2.01e-2)" "unprognostic (3.10e-1)" "unprognostic (2.31e-1)" "unprognostic (6.41e-2)" "unprognostic (2.72e-2)" "unprognostic (2.81e-3)" "unprognostic (3.31e-2)" "unprognostic (1.81e-2)" "unprognostic (7.07e-3)" "unprognostic (1.22e-3)" "unprognostic (4.66e-2)" "unprognostic (1.54e-1)" "unprognostic (5.17e-2)" "unprognostic (8.26e-2)" "potential prognostic favorable (3.91e-5)" "unprognostic (3.33e-1)" "unprognostic (5.92e-3)" "unprognostic (2.20e-3)" "unprognostic (1.99e-3)" "unprognostic (1.16e-1)" "unprognostic (1.40e-3)" "unprognostic (2.39e-2)" "unprognostic (1.99e-1)" "unprognostic (4.60e-3)" "unprognostic (2.23e-1)" "unprognostic (2.54e-1)" "unprognostic (2.36e-1)" TRIM26 "RNF95, ZNF173" ENSG00000234127 "Tripartite motif containing 26" Q12899 6 30184455-30213427 "Enzymes, Predicted intracellular proteins" "Immunity, Innate immunity" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 25.5;Brain excitatory neurons: 23.5;Brain inhibitory neurons: 26.4;Choroid plexus epithelial cells: 48.0;Distal convoluted tubule cells: 66.9;Loop of henle epithelial cells: 52.3;Microglia: 29.8;Oligodendrocyte progenitor cells: 28.6;Oligodendrocytes: 34.6;Other brain neurons: 23.3;Papillary tip epithelial cells: 50.2;Podocytes: 30.5;Proximal tubule cells: 61.6;Renal collecting duct intercalated cells: 53.5;Renal collecting duct principal cells: 46.3;Renal connecting tubule cells: 53.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044975, HPA050456" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 28: Non-specific - Nuclear processes" "Cluster 102: Non-specific - Mixed function" 30 "Nucleoplasm, Cytosol" "HPA044975: , HPA050456: " "unprognostic (1.74e-1)" "unprognostic (1.14e-1)" "unprognostic (1.90e-1)" "unprognostic (3.42e-2)" "unprognostic (1.22e-1)" "unprognostic (2.55e-2)" "unprognostic (3.96e-2)" "unprognostic (6.44e-2)" "unprognostic (1.77e-2)" "unprognostic (2.39e-2)" "potential prognostic favorable (1.72e-4)" "unprognostic (1.55e-2)" "unprognostic (5.89e-2)" "unprognostic (4.12e-2)" "unprognostic (7.91e-2)" "unprognostic (5.60e-2)" "unprognostic (7.54e-2)" "unprognostic (4.38e-2)" "unprognostic (3.21e-1)" "unprognostic (3.40e-1)" "unprognostic (6.08e-2)" "unprognostic (1.26e-1)" "unprognostic (3.65e-1)" "unprognostic (4.24e-2)" "unprognostic (9.55e-3)" "unprognostic (3.93e-1)" "unprognostic (2.72e-2)" "unprognostic (4.79e-3)" "unprognostic (1.30e-1)" "unprognostic (6.28e-2)" "unprognostic (1.59e-1)" TRIM27 "RFP, RNF76" ENSG00000204713 "Tripartite motif containing 27" P14373 6 28903002-28923988 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation, Transport, Ubl conjugation pathway" "DNA-binding, Repressor, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 24.4;Brain inhibitory neurons: 22.1;Choroid plexus epithelial cells: 47.4;Distal convoluted tubule cells: 32.6;Loop of henle epithelial cells: 27.7;Microglia: 62.6;Oligodendrocyte progenitor cells: 27.8;Oligodendrocytes: 30.2;Other brain neurons: 30.1;Papillary tip epithelial cells: 29.2;Podocytes: 26.6;Proximal tubule cells: 38.2;Renal collecting duct intercalated cells: 41.1;Renal collecting duct principal cells: 31.8;Renal connecting tubule cells: 33.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048684, HPA053408" Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 70: Non-specific - Protein processing" "Cluster 7: Non-specific - Ribosome" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 102: Non-specific - Mixed function" 318 Nucleoli Nucleoplasm "HPA048684: , HPA053408: " "unprognostic (7.29e-2)" "unprognostic (1.04e-1)" "unprognostic (5.07e-2)" "unprognostic (2.27e-2)" "unprognostic (3.40e-2)" "unprognostic (1.34e-1)" "unprognostic (4.71e-2)" "potential prognostic favorable (6.00e-5)" "unprognostic (5.32e-2)" "unprognostic (1.57e-1)" "unprognostic (6.16e-3)" "unprognostic (9.71e-2)" "unprognostic (1.84e-2)" "unprognostic (1.07e-1)" "unprognostic (2.97e-3)" "unprognostic (1.50e-1)" "unprognostic (2.97e-1)" "unprognostic (1.46e-1)" "unprognostic (1.61e-1)" "unprognostic (3.21e-1)" "unprognostic (1.40e-1)" "potential prognostic favorable (3.18e-4)" "unprognostic (1.32e-1)" "unprognostic (2.30e-1)" "unprognostic (5.56e-2)" "unprognostic (1.06e-1)" "unprognostic (3.56e-2)" "unprognostic (2.04e-1)" "unprognostic (1.62e-1)" "unprognostic (6.41e-2)" "unprognostic (2.17e-1)" TRIM28 "KAP-1, KAP1, PPP1R157, RNF96, TF1B, TIF1-beta, TIF1B, TIF1beta" ENSG00000130726 "Tripartite motif containing 28" Q13263 19 58544064-58550722 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation, Ubl conjugation pathway" "Chromatin regulator, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 300.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010066, HPA064033" Supported Enhanced Nucleoplasm NA NA 130000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 54: Non-specific - Ribosome" "Cluster 55: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 20: Non-specific - Transcription regulation" 641 Nucleoplasm "CAB010066: , HPA064033: " "unprognostic (1.77e-1)" "unprognostic (3.20e-1)" "unprognostic (1.16e-1)" "unprognostic (1.59e-1)" "unprognostic (5.95e-2)" "unprognostic (1.10e-1)" "unprognostic (1.85e-1)" "unprognostic (9.08e-2)" "unprognostic (1.02e-1)" "unprognostic (1.31e-1)" "unprognostic (1.36e-3)" "unprognostic (2.74e-1)" "unprognostic (2.73e-2)" "validated prognostic unfavorable (1.56e-9)" "validated prognostic unfavorable (5.28e-5)" "potential prognostic unfavorable (2.93e-4)" "unprognostic (9.29e-3)" "unprognostic (5.09e-2)" "unprognostic (1.70e-2)" "unprognostic (1.50e-1)" "unprognostic (5.89e-2)" "unprognostic (1.83e-1)" "unprognostic (3.05e-1)" "unprognostic (2.82e-1)" "unprognostic (4.62e-2)" "unprognostic (1.72e-2)" "unprognostic (7.95e-2)" "unprognostic (3.28e-1)" "unprognostic (2.04e-1)" "unprognostic (4.60e-2)" "unprognostic (2.79e-2)" TRIM29 "ATDC, FLJ36085" ENSG00000137699 "Tripartite motif containing 29" Q14134 11 120111286-120185529 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 699.7;skin 1: 719.7;vagina: 361.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 435.0;Esophageal apical cells: 1446.3;Esophageal basal cells: 674.8;Esophageal suprabasal cells: 1241.9;Late spermatids: 252.4;Ocular epithelial cells: 820.3;Suprabasal keratinocytes: 911.8" "Cell type enhanced" "Detected in some" "ependymal cell: 17.9" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 386.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 203.7;Gallbladder cancer: 155.6;head and neck cancer: 155.4" "Adipose visceral - Mesothelial cells, Breast - Breast myoepithelial cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary gland basal cells, Pituitary gland - Corticotropes, Skin - Keratinocyte (other), Testis - Late spermatids" "Not detected" "Not detected" "Region enriched" "Detected in single" 9 "spinal cord: 5.3" "HPA020053, HPA074841" Enhanced Approved "Nucleoplasm,Intermediate filaments,Cytosol" NA NA 36000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 45 "Intermediate filaments" "Nucleoplasm, Cytosol" "HPA020053: , HPA074841: " "unprognostic (3.96e-2)" "unprognostic (1.26e-1)" "unprognostic (4.41e-1)" "unprognostic (1.63e-1)" "unprognostic (1.34e-1)" "unprognostic (1.63e-2)" "unprognostic (9.99e-2)" "unprognostic (2.66e-1)" "unprognostic (1.95e-2)" "potential prognostic unfavorable (6.62e-4)" "unprognostic (8.81e-2)" "unprognostic (1.68e-1)" "unprognostic (7.76e-2)" "unprognostic (5.04e-2)" "unprognostic (5.67e-2)" "potential prognostic unfavorable (4.33e-5)" "unprognostic (1.54e-1)" "unprognostic (2.80e-1)" "unprognostic (3.58e-1)" "unprognostic (7.26e-2)" "unprognostic (1.24e-1)" "potential prognostic favorable (3.42e-4)" "unprognostic (1.74e-1)" "unprognostic (7.73e-2)" "unprognostic (1.10e-1)" TRIM3 "BERP, HAC1, RNF22, RNF97" ENSG00000110171 "Tripartite motif containing 3" O75382 11 6448613-6474459 "Predicted intracellular proteins" "Protein transport, Transport" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 49.0" "Cell type enhanced" "Detected in many" "Enterocytes: 37.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Minor Salivary Gland - Smooth muscle cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043396, HPA048233" Enhanced Approved Mitochondria NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 65: Non-specific - Cell growth & division" 30 Mitochondria "HPA043396: , HPA048233: " "unprognostic (1.28e-2)" "unprognostic (1.63e-2)" "unprognostic (2.88e-2)" "unprognostic (7.34e-2)" "unprognostic (4.44e-1)" "unprognostic (6.42e-2)" "unprognostic (2.41e-2)" "unprognostic (1.24e-1)" "unprognostic (6.76e-2)" "unprognostic (3.89e-1)" "potential prognostic favorable (7.45e-4)" "unprognostic (5.49e-2)" "unprognostic (1.94e-1)" "unprognostic (7.90e-2)" "unprognostic (4.81e-2)" "unprognostic (4.21e-1)" "unprognostic (9.91e-2)" "unprognostic (2.16e-2)" "unprognostic (7.88e-2)" "unprognostic (8.85e-2)" "unprognostic (1.13e-1)" "unprognostic (1.03e-2)" "unprognostic (6.21e-2)" "unprognostic (1.89e-1)" "unprognostic (4.37e-2)" "unprognostic (1.75e-1)" "unprognostic (2.74e-1)" "unprognostic (1.43e-1)" "unprognostic (2.42e-1)" "unprognostic (3.64e-2)" "unprognostic (7.99e-2)" TRIM31 "C6orf13, HCG1, HCGI, RNF" ENSG00000204616 "Tripartite motif containing 31" Q9BZY9 6 30102897-30113090 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Inflammatory response, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 20.7;stomach 1: 5.6;urinary bladder: 15.7" "Cell type enhanced" "Detected in some" "Colonocytes: 14.7;Endometrial ciliated cells: 5.9;Endometrial secretory cells: 8.8;Enterocytes: 10.9;Foveolar cells: 9.8;Papillary tip epithelial cells: 14.0;Prostatic club cells: 21.3;Prostatic hillock cells: 17.6;Urothelial cells: 65.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 9.7;Rectum Adenocarcinoma (TCGA): 9.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 6.7;Bladder cancer: 9.8" "Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Prostate - Urothelial cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA074175 Enhanced NA NA "Cluster 77: Intestine - Digestion" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 69: Urothelial cells - Basic cellular functions" 20 "HPA074175: " "unprognostic (5.48e-1)" "unprognostic (4.44e-1)" "unprognostic (3.92e-1)" "unprognostic (1.52e-3)" "unprognostic (4.56e-1)" "potential prognostic unfavorable (1.54e-5)" "unprognostic (4.69e-1)" "unprognostic (8.94e-2)" "unprognostic (5.03e-2)" "unprognostic (7.32e-2)" "unprognostic (9.89e-2)" "unprognostic (1.15e-1)" TRIM32 "BBS11, HT2A, LGMD2H, TATIP" ENSG00000119401 "Tripartite motif containing 32" Q13049 9 116687305-116701300 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Intellectual disability, Limb-girdle muscular dystrophy, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 26.9;Decidual stromal cells: 28.9;Thymic myoid cells: 35.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050060 Approved Approved "Intermediate filaments" No No "Cluster 39: T-cells - T-cell receptor" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 5: Non-specific - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 95 "Intermediate filaments" "HPA050060: " "unprognostic (1.31e-1)" "unprognostic (1.31e-2)" "unprognostic (8.91e-2)" "unprognostic (3.52e-3)" "unprognostic (3.49e-2)" "unprognostic (1.67e-1)" "unprognostic (1.99e-1)" "unprognostic (3.32e-2)" "unprognostic (4.59e-3)" "unprognostic (7.14e-3)" "potential prognostic favorable (1.30e-5)" "unprognostic (5.31e-2)" "unprognostic (1.75e-1)" "unprognostic (3.36e-3)" "unprognostic (4.74e-2)" "unprognostic (6.65e-2)" "unprognostic (2.29e-1)" "unprognostic (3.37e-2)" "unprognostic (3.28e-2)" "unprognostic (3.25e-2)" "unprognostic (9.23e-2)" "unprognostic (2.51e-2)" "unprognostic (1.86e-1)" "unprognostic (1.58e-2)" "unprognostic (6.64e-2)" "unprognostic (3.32e-1)" "unprognostic (3.31e-1)" "unprognostic (3.26e-2)" "unprognostic (2.15e-1)" "unprognostic (2.15e-1)" "unprognostic (1.76e-1)" TRIM33 "FLJ11429, KIAA1113, PTC7, RFG7, TF1G, TIF1G, TIF1GAMMA, TIFGAMMA" ENSG00000197323 "Tripartite motif containing 33" Q9UPN9 1 114392790-114511203 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "DNA-binding, Repressor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 13.2" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004345 Supported Approved Nucleoplasm,Vesicles NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 22: Epididymis - Mixed function" "Cluster 16: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 51: Secretory epithelial cells - Mixed function" 65 Vesicles Nucleoplasm "HPA004345: " "unprognostic (1.36e-2)" "unprognostic (1.47e-1)" "unprognostic (8.25e-2)" "unprognostic (3.15e-1)" "unprognostic (1.00e-2)" "unprognostic (1.28e-1)" "unprognostic (5.24e-2)" "unprognostic (4.28e-3)" "unprognostic (2.37e-2)" "unprognostic (4.16e-3)" "validated prognostic favorable (1.57e-5)" "validated prognostic favorable (7.51e-4)" "unprognostic (2.70e-1)" "unprognostic (9.25e-3)" "unprognostic (1.54e-1)" "unprognostic (1.16e-1)" "unprognostic (2.93e-2)" "unprognostic (3.16e-2)" "unprognostic (1.99e-2)" "unprognostic (1.53e-1)" "unprognostic (9.37e-3)" "unprognostic (7.47e-2)" "unprognostic (6.84e-3)" "unprognostic (1.29e-1)" "unprognostic (7.49e-3)" "unprognostic (6.05e-2)" "unprognostic (9.82e-3)" "unprognostic (2.40e-1)" "unprognostic (2.67e-1)" "unprognostic (5.61e-3)" "unprognostic (7.46e-2)" TRIM34 RNF21 ENSG00000258659 "Tripartite motif containing 34" Q9BYJ4 11 5619764-5644398 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 6 "Microglia: 27.7" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 34.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077996 Approved Nucleoli,Centrosome NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 4 Centrosome Nucleoli "HPA077996: " "unprognostic (2.63e-1)" "unprognostic (2.29e-3)" "unprognostic (1.35e-1)" "unprognostic (4.88e-2)" "unprognostic (3.56e-3)" "unprognostic (4.36e-1)" "unprognostic (8.80e-2)" "unprognostic (1.60e-2)" "unprognostic (1.94e-1)" "unprognostic (1.11e-1)" "potential prognostic favorable (1.31e-4)" "unprognostic (3.72e-1)" "unprognostic (1.13e-2)" "unprognostic (3.59e-3)" "potential prognostic favorable (2.95e-4)" "unprognostic (2.06e-1)" "unprognostic (1.54e-2)" "unprognostic (2.53e-2)" "unprognostic (9.06e-3)" "unprognostic (1.14e-1)" "unprognostic (1.48e-1)" "unprognostic (5.21e-2)" "unprognostic (3.13e-1)" "unprognostic (1.86e-1)" "potential prognostic favorable (4.11e-4)" "unprognostic (1.28e-1)" "unprognostic (3.97e-1)" "unprognostic (2.31e-2)" "unprognostic (1.10e-1)" "unprognostic (1.89e-1)" "unprognostic (4.68e-2)" TRIM35 "HLS5, KIAA1098, MAIR" ENSG00000104228 "Tripartite motif containing 35" Q9UPQ4 8 27284886-27311272 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 47.3;Hepatocytes: 50.3;Tuft cells: 46.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019647 Approved Approved Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 58: Skin - Keratinization" "Cluster 30: White matter - Myelination" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 93: Hepatocytes - Bile production & excretion" 17 Nucleoplasm "HPA019647: " "unprognostic (1.15e-3)" "unprognostic (2.97e-2)" "potential prognostic favorable (1.27e-5)" "unprognostic (1.47e-1)" "unprognostic (8.21e-3)" "unprognostic (1.12e-1)" "unprognostic (5.77e-2)" "potential prognostic favorable (5.98e-5)" "unprognostic (5.03e-3)" "unprognostic (1.04e-3)" "validated prognostic favorable (7.43e-5)" "validated prognostic favorable (2.32e-4)" "unprognostic (1.70e-3)" "unprognostic (1.24e-1)" "unprognostic (2.31e-2)" "unprognostic (3.23e-2)" "unprognostic (1.63e-1)" "unprognostic (1.30e-1)" "unprognostic (8.24e-2)" "unprognostic (7.42e-2)" "unprognostic (1.77e-2)" "unprognostic (9.24e-2)" "unprognostic (2.61e-2)" "unprognostic (1.53e-1)" "unprognostic (1.02e-1)" "unprognostic (4.35e-2)" "unprognostic (8.33e-2)" "unprognostic (1.25e-1)" "unprognostic (1.67e-1)" "unprognostic (2.74e-1)" "unprognostic (4.53e-1)" TRIM36 "HAPRIN, RBCC728, RNF98" ENSG00000152503 "Tripartite motif containing 36" Q9NQ86 5 115124762-115180546 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "retina: 40.9;testis: 162.8" "Group enriched" "Detected in many" 7 "Early spermatids: 2529.3;Late spermatids: 7747.3" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Glioblastoma Multiforme (TCGA): 13.9;Prostate Adenocarcinoma (TCGA): 36.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 5.8;non-classical monocyte: 6.5" "Group enriched" "Detected in many" 48 "dendritic cells: 5.8;granulocytes: 3.2;monocytes: 6.5" "Cancer enhanced" "Detected in many" "prostate cancer: 22.2" "Breast - Breast glandular cells, Prostate - Prostate glandular cells, Stomach - Chief cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004696 Supported "Plasma membrane,Cytosol" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 47: Testis - Mixed function" "Cluster 14: Neurons - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 11 Cytosol "Plasma membrane" "HPA004696: " "unprognostic (2.44e-2)" "unprognostic (1.57e-3)" "unprognostic (3.92e-2)" "unprognostic (2.66e-2)" "unprognostic (1.11e-1)" "unprognostic (1.95e-1)" "unprognostic (6.47e-3)" "potential prognostic unfavorable (1.97e-5)" "unprognostic (3.75e-2)" "unprognostic (4.26e-1)" "unprognostic (1.36e-1)" "unprognostic (4.52e-3)" "unprognostic (3.60e-1)" "unprognostic (1.13e-1)" "unprognostic (1.70e-1)" "potential prognostic unfavorable (2.17e-4)" "unprognostic (2.25e-1)" "unprognostic (4.32e-2)" "unprognostic (4.14e-2)" "unprognostic (1.68e-2)" "unprognostic (1.24e-1)" "unprognostic (3.71e-1)" "unprognostic (2.79e-1)" "unprognostic (5.86e-2)" TRIM37 "KIAA0898, MUL, POB1, TEF3" ENSG00000108395 "Tripartite motif containing 37" O94972 17 58982638-59106921 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Transcription, Ubl conjugation pathway" "Repressor, Transferase" "Dwarfism, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 58.2" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 225.6;Late primary spermatocytes: 193.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 30.5" "Group enriched" "Detected in all" 5 "granulocytes: 30.5;T-cells: 8.3" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021911 Uncertain NA NA "Cluster 41: Basophils - Unknown function" "Cluster 27: Cerebellum - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" 86 "HPA021911: " "unprognostic (2.27e-1)" "unprognostic (1.06e-1)" "unprognostic (1.77e-2)" "unprognostic (2.04e-1)" "unprognostic (2.85e-1)" "unprognostic (1.65e-2)" "unprognostic (1.51e-1)" "unprognostic (7.74e-3)" "unprognostic (2.30e-1)" "unprognostic (7.68e-2)" "unprognostic (2.80e-2)" "unprognostic (1.57e-1)" "unprognostic (4.62e-3)" "validated prognostic unfavorable (5.73e-5)" "validated prognostic unfavorable (4.08e-6)" "unprognostic (3.19e-2)" "unprognostic (1.90e-1)" "unprognostic (1.05e-1)" "unprognostic (3.84e-2)" "unprognostic (8.47e-2)" "unprognostic (2.41e-1)" "unprognostic (3.79e-3)" "unprognostic (4.74e-2)" "unprognostic (8.94e-2)" "unprognostic (8.97e-2)" "unprognostic (6.73e-3)" "unprognostic (1.29e-1)" "unprognostic (2.27e-1)" "unprognostic (2.76e-1)" "unprognostic (5.07e-2)" "unprognostic (8.49e-2)" TRIM38 "RNF15, RORET" ENSG00000112343 "Tripartite motif containing 38" O00635 6 25962802-25991231 "Enzymes, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Neutrophils: 170.5;Thymic myoid cells: 190.3" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 172.8;endothelial cell: 81.3;leukocyte: 97.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Kidney - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA031685 Approved Approved "Plasma membrane,Cell Junctions,Centrosome" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 22 Centrosome "Plasma membrane, Cell Junctions" "HPA031685: " "unprognostic (1.84e-3)" "unprognostic (1.38e-1)" "unprognostic (2.29e-1)" "unprognostic (9.78e-2)" "unprognostic (3.06e-1)" "unprognostic (2.56e-1)" "unprognostic (1.51e-1)" "unprognostic (9.60e-3)" "unprognostic (2.43e-1)" "potential prognostic unfavorable (8.84e-5)" "unprognostic (2.88e-2)" "unprognostic (3.24e-2)" "potential prognostic favorable (4.48e-4)" "unprognostic (4.98e-2)" "unprognostic (1.97e-2)" "unprognostic (3.68e-2)" "unprognostic (1.75e-1)" "unprognostic (2.73e-1)" "unprognostic (1.29e-1)" "unprognostic (5.34e-3)" "unprognostic (1.78e-2)" "unprognostic (2.96e-2)" "unprognostic (1.52e-2)" "unprognostic (1.89e-1)" "unprognostic (2.26e-2)" "unprognostic (1.22e-1)" "unprognostic (1.98e-2)" "unprognostic (3.58e-1)" "unprognostic (9.08e-2)" "unprognostic (1.00e-1)" "unprognostic (1.60e-1)" TRIM39 RNF23 ENSG00000204599 "Tripartite motif containing 39" Q9HCM9 6 30326479-30343729 "Enzymes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 7 "Astrocytes: 6.9;Bergmann glia: 6.6;Brain excitatory neurons: 5.3;Brain inhibitory neurons: 5.6;Choroid plexus epithelial cells: 12.3;Ependymal cells: 15.2;Microglia: 6.7;Oligodendrocyte progenitor cells: 6.1;Oligodendrocytes: 6.4;Other brain neurons: 5.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051120, HPA059496" Uncertain Supported Cytosol NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 64: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 22: Non-specific - Basic cellular functions" 53 Cytosol "HPA051120: , HPA059496: " "unprognostic (2.70e-2)" "unprognostic (1.43e-1)" "unprognostic (2.54e-1)" "unprognostic (5.91e-3)" "unprognostic (1.25e-1)" "unprognostic (1.80e-1)" "unprognostic (2.24e-1)" "unprognostic (1.95e-2)" "unprognostic (1.25e-1)" "unprognostic (6.58e-3)" "unprognostic (2.81e-2)" "unprognostic (8.83e-2)" "unprognostic (1.70e-1)" "unprognostic (2.53e-2)" "unprognostic (3.15e-2)" "unprognostic (1.78e-1)" "unprognostic (8.34e-2)" "unprognostic (3.28e-1)" "unprognostic (1.20e-1)" "unprognostic (1.23e-1)" "unprognostic (1.27e-1)" "unprognostic (7.64e-2)" "unprognostic (3.08e-1)" "unprognostic (1.82e-1)" "unprognostic (2.01e-1)" "unprognostic (6.45e-3)" "unprognostic (4.74e-2)" "unprognostic (6.10e-2)" "unprognostic (1.65e-3)" "unprognostic (2.33e-1)" TRIM39-RPP21 ENSG00000248167 "TRIM39-RPP21 readthrough" 6 30328907-30346854 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA051120 Uncertain Approved Cytosol NA NA Cytosol "HPA051120: " TRIM4 RNF87 ENSG00000146833 "Tripartite motif containing 4" Q9C037 7 99876958-99919531 "Enzymes, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019356, HPA029461" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 39: Non-specific - Transcription" "Cluster 9: T-cells - Adaptive immunity: Regulation" 4 Cytosol "Plasma membrane" "HPA019356: , HPA029461: " "unprognostic (1.71e-2)" "unprognostic (1.15e-1)" "unprognostic (1.60e-2)" "potential prognostic unfavorable (9.52e-4)" "unprognostic (3.41e-1)" "unprognostic (6.36e-2)" "unprognostic (1.82e-2)" "unprognostic (1.07e-1)" "unprognostic (1.28e-1)" "unprognostic (2.52e-2)" "potential prognostic favorable (1.98e-8)" "unprognostic (3.76e-3)" "unprognostic (1.07e-3)" "unprognostic (7.71e-2)" "unprognostic (5.58e-2)" "unprognostic (4.01e-1)" "unprognostic (1.57e-2)" "unprognostic (4.77e-1)" "unprognostic (1.31e-1)" "unprognostic (2.00e-2)" "unprognostic (1.57e-1)" "unprognostic (9.11e-2)" "unprognostic (8.52e-3)" "unprognostic (8.94e-2)" "unprognostic (3.05e-2)" "unprognostic (3.00e-1)" "unprognostic (1.18e-1)" "unprognostic (1.26e-1)" "unprognostic (1.26e-1)" "unprognostic (1.38e-1)" "unprognostic (2.19e-2)" TRIM40 RNF35 ENSG00000204614 "Tripartite motif containing 40" Q6P9F5 6 30136124-30148735 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "intestine: 2.9;liver: 1.4;testis: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enterocytes, Stomach - Gastric mucous cells" "Region enriched" "Detected in single" 18 "thalamus: 3.1" "Low region specificity" "Detected in all" HPA043818 Uncertain Approved Cytosol NA NA "Cluster 21: Testis - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 2 Cytosol "HPA043818: " TRIM41 "MGC1127, RINCK" ENSG00000146063 "Tripartite motif containing 41" Q8WV44 5 181222499-181235808 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "brain: 76.8;skeletal muscle: 24.4" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024204 Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol" NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 47: Endothelial cells - Vasculature" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 135 "Nucleoli fibrillar center" "Nucleoplasm, Vesicles, Cytosol" "HPA024204: " "unprognostic (4.09e-1)" "unprognostic (1.01e-1)" "unprognostic (2.03e-1)" "unprognostic (1.64e-2)" "unprognostic (2.11e-1)" "unprognostic (1.34e-1)" "unprognostic (6.62e-2)" "unprognostic (8.84e-3)" "unprognostic (2.06e-1)" "unprognostic (1.97e-1)" "potential prognostic favorable (5.72e-9)" "unprognostic (1.49e-2)" "potential prognostic favorable (2.99e-5)" "unprognostic (5.03e-2)" "unprognostic (5.08e-2)" "unprognostic (9.12e-2)" "unprognostic (3.05e-2)" "unprognostic (3.14e-2)" "unprognostic (5.06e-2)" "unprognostic (1.56e-1)" "unprognostic (7.56e-2)" "unprognostic (3.33e-2)" "unprognostic (1.14e-2)" "unprognostic (1.45e-1)" "unprognostic (1.12e-1)" "unprognostic (1.81e-2)" "unprognostic (2.53e-1)" "unprognostic (1.10e-1)" "unprognostic (7.03e-2)" "unprognostic (6.16e-3)" "unprognostic (1.58e-1)" TRIM42 "FLJ40097, PPP1R40, T4A1" ENSG00000155890 "Tripartite motif containing 42" Q8IWZ5 3 140678064-140701150 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 159 "testis: 15.9" "Group enriched" "Detected in some" 15 "Early spermatids: 319.7;Late spermatids: 211.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 112 TRIM43 TRIM43A ENSG00000144015 "Tripartite motif containing 43" Q96BQ3 2 95592001-95599778 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Gastric chief cells: 1.1" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 1.0;Uterine Corpus Endometrial Carcinoma (TCGA): 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "ovarian cancer: 1.0" "HPA042223, HPA042772" Uncertain NA NA "Cluster 15: Kidney cancer - Membrane components" "Cluster 97: Non-specific - Cellular respiration" 26 "HPA042223: , HPA042772: " "unprognostic (1.31e-1)" "unprognostic (1.72e-2)" TRIM43B ENSG00000144010 "Tripartite motif containing 43B" A6NCK2 2 95477008-95484754 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Testicular Germ Cell Tumor (TCGA): 1.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA042223, HPA042772" Uncertain NA NA "Cluster 11: Neuronal - Sensory perception" "HPA042223: , HPA042772: " "unprognostic (4.82e-2)" TRIM44 "DIPB, MC7" ENSG00000166326 "Tripartite motif containing 44" Q96DX7 11 35662775-35818007 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049053, HPA057633" Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 37: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 7: Non-specific - Transcription" 14 Vesicles "Plasma membrane" "HPA049053: , HPA057633: " "unprognostic (2.07e-3)" "unprognostic (2.62e-1)" "unprognostic (1.24e-1)" "unprognostic (2.16e-2)" "unprognostic (3.34e-1)" "unprognostic (8.56e-3)" "unprognostic (1.01e-1)" "unprognostic (6.86e-2)" "unprognostic (5.31e-2)" "potential prognostic unfavorable (3.44e-5)" "validated prognostic favorable (2.05e-5)" "validated prognostic favorable (2.44e-4)" "unprognostic (1.21e-1)" "potential prognostic unfavorable (3.65e-4)" "unprognostic (6.59e-2)" "unprognostic (1.94e-1)" "unprognostic (4.18e-2)" "unprognostic (1.06e-1)" "unprognostic (2.99e-2)" "unprognostic (1.16e-1)" "unprognostic (2.57e-3)" "unprognostic (4.18e-2)" "unprognostic (2.00e-2)" "unprognostic (2.11e-1)" "unprognostic (3.49e-2)" "unprognostic (9.37e-2)" "unprognostic (1.48e-1)" "unprognostic (8.28e-2)" "unprognostic (9.13e-2)" "unprognostic (3.83e-2)" "unprognostic (4.35e-1)" TRIM45 "FLJ13181, RNF99" ENSG00000134253 "Tripartite motif containing 45" Q9H8W5 1 117111060-117122587 "Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 27.3" "Cell type enhanced" "Detected in many" "Myonuclei: 24.6" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 18.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030266, HPA054308" Uncertain Supported "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes No "Cluster 24: Non-specific - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 3 Cytosol "Nucleoplasm, Cytokinetic bridge" "HPA030266: , HPA054308: " "unprognostic (9.84e-2)" "unprognostic (1.32e-3)" "unprognostic (3.14e-1)" "unprognostic (2.00e-1)" "unprognostic (4.36e-2)" "unprognostic (1.08e-1)" "unprognostic (9.92e-2)" "potential prognostic favorable (6.37e-4)" "unprognostic (3.13e-1)" "unprognostic (1.15e-2)" "unprognostic (1.99e-1)" "unprognostic (1.86e-1)" "potential prognostic favorable (1.61e-4)" "potential prognostic unfavorable (7.18e-4)" "unprognostic (5.27e-2)" "unprognostic (1.82e-1)" "unprognostic (2.82e-1)" "unprognostic (1.41e-3)" "unprognostic (1.48e-3)" "unprognostic (1.22e-1)" "unprognostic (1.56e-2)" "unprognostic (4.54e-2)" "unprognostic (7.49e-2)" "unprognostic (4.66e-2)" "unprognostic (4.30e-2)" "unprognostic (1.95e-2)" "unprognostic (4.65e-2)" "unprognostic (4.30e-2)" "unprognostic (2.33e-2)" "potential prognostic unfavorable (5.03e-5)" "unprognostic (2.84e-1)" TRIM46 "FLJ23229, TRIFIC" ENSG00000163462 "Tripartite motif containing 46" Q7Z4K8 1 155173787-155184971 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 21.5" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 20.3;Brain inhibitory neurons: 21.0;Breast lactating cells: 20.6;Epicardial cells: 25.0;Epididymal principal cells: 12.5;Late spermatids: 12.5;Oligodendrocytes: 10.7;Other brain neurons: 17.0;Retinal amacrine cells: 20.2;Retinal ganglion cells: 15.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 9.7" "Adrenal gland - Adrenal medulla cells, Pancreas - Alpha cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030391, HPA055583" Enhanced Approved "Microtubule ends,Cytokinetic bridge,Mitotic spindle,Primary cilium transition zone,Centrosome,Cytosol" Yes NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 34: Non-specific - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" "Microtubule ends, Mitotic spindle, Primary cilium transition zone" "Cytokinetic bridge, Centrosome, Cytosol" "HPA030391: , HPA055583: " "unprognostic (3.96e-2)" "unprognostic (2.26e-1)" "unprognostic (3.26e-1)" "unprognostic (2.47e-2)" "unprognostic (5.00e-2)" "unprognostic (3.01e-1)" "potential prognostic favorable (4.90e-4)" "unprognostic (9.44e-2)" "unprognostic (3.00e-2)" "unprognostic (1.87e-1)" "unprognostic (1.43e-2)" "unprognostic (3.60e-1)" "unprognostic (3.12e-3)" "unprognostic (9.76e-3)" "unprognostic (8.50e-2)" "unprognostic (6.13e-2)" "unprognostic (1.60e-1)" "unprognostic (4.79e-1)" "unprognostic (2.11e-2)" TRIM47 "GOA, RNF100" ENSG00000132481 "Tripartite motif containing 47" Q96LD4 17 75874164-75878581 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 65.0;Esophageal basal cells: 59.8;Hofbauer cells: 106.9;Pancreatic duct cells: 88.0" "Cell type enhanced" "Detected in many" "astrocyte: 44.0;Bergmann glia: 38.2;endothelial cell: 28.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014933 Uncertain Supported Cytosol NA NA "Cluster 27: T-cells - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 19: Astrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 11 Cytosol "HPA014933: " "unprognostic (1.55e-1)" "unprognostic (9.45e-3)" "unprognostic (1.32e-2)" "unprognostic (2.73e-1)" "unprognostic (1.70e-2)" "unprognostic (5.76e-2)" "unprognostic (2.86e-3)" "unprognostic (2.52e-1)" "unprognostic (7.77e-2)" "unprognostic (5.39e-2)" "potential prognostic unfavorable (1.68e-7)" "unprognostic (2.42e-1)" "unprognostic (2.32e-2)" "unprognostic (1.19e-3)" "potential prognostic unfavorable (2.60e-4)" "unprognostic (6.26e-2)" "unprognostic (2.78e-2)" "unprognostic (1.25e-1)" "potential prognostic unfavorable (9.28e-4)" "unprognostic (5.12e-1)" "potential prognostic favorable (4.19e-4)" "unprognostic (2.19e-3)" "unprognostic (3.09e-2)" "unprognostic (2.33e-1)" "unprognostic (7.46e-2)" "unprognostic (8.68e-2)" "unprognostic (3.31e-1)" "unprognostic (1.22e-1)" "unprognostic (5.36e-2)" "potential prognostic favorable (2.07e-4)" "unprognostic (1.44e-1)" TRIM48 RNF101 ENSG00000150244 "Tripartite motif containing 48" Q8IWZ4 11 55262155-55271114 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Gastric chief cells: 1.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Lung Adenocarcinoma (TCGA): 1.8;Skin Cutaneous Melanoma (TCGA): 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 20 "cervical cancer: 40.6" NA NA "Cluster 32: Non-specific - Cell proliferation" "Cluster 68: Foveolar cells - Mucosal defense" 2 "unprognostic (1.22e-2)" TRIM49 "RNF18, TRIM49A" ENSG00000168930 "Tripartite motif containing 49" P0CI25 11 89797655-89808575 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 9 "Undifferentiated spermatogonia: 4.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 50: Lymphoma - Unknown function" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 9 TRIM49B ENSG00000182053 "Tripartite motif containing 49B" A6NDI0 11 49027501-49038451 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Retinal horizontal cells: 2.0" "Cell type enhanced" "Detected in single" "lower rhombic lip: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 8 "cervical cancer: 1.3" NA NA "Cluster 32: Non-specific - Cell proliferation" "Cluster 109: Neurons - Neuronal signaling" TRIM49C TRIM49L2 ENSG00000204449 "Tripartite motif containing 49C" P0CI26 11 90031106-90042025 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Gastric chief cells: 1.1;Undifferentiated spermatogonia: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 27: Breast cancer - Unknown function" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 3 TRIM49D1 "TRIM49D, TRIM49D1P, TRIM49DP" ENSG00000223417 "Tripartite motif containing 49D1" C9J1S8 11 89911111-89922245 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "liver: 3.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 33 "basophil: 15.1" "Lineage enriched" "Detected in single" 33 "granulocytes: 15.1" "Cancer enhanced" "Detected in many" "prostate cancer: 5.5" HPA072153 Approved Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 9: Non-specific - Receptor signaling" "Cluster 60: Prostate cancer - Unknown function" Nucleoplasm Cytosol "HPA072153: " TRIM49D2 "TRIM49D2P, TRIM49L, TRIM49L1" ENSG00000233802 "Tripartite motif containing 49D2" C9J1S8 11 89924064-89933063 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 320 "basophil: 32.0" "Lineage enriched" "Detected in single" 320 "granulocytes: 32.0" "Cancer enriched" "Detected in single" 19 "prostate cancer: 1.9" HPA072153 Approved Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 60: Prostate cancer - Unknown function" Nucleoplasm Cytosol "HPA072153: " TRIM5 "RNF88, TRIM5alpha" ENSG00000132256 "Tripartite motif containing 5" Q9C035 11 5663195-5938619 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Antiviral defense, Autophagy, Host-virus interaction, Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibro-adipogenic progenitors: 119.8;Hematopoietic stem cells: 413.4;Plasma cells: 99.2" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 74.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "CAB013497, HPA023420, HPA023422" Approved Supported Cytosol NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 22: Epididymis - Mixed function" "Cluster 8: Immune cells - Immune response" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 17 Cytosol "CAB013497: , HPA023420: , HPA023422: " "unprognostic (2.17e-2)" "unprognostic (6.62e-2)" "unprognostic (8.84e-2)" "unprognostic (1.01e-2)" "unprognostic (2.54e-1)" "unprognostic (1.73e-1)" "unprognostic (7.23e-2)" "potential prognostic unfavorable (1.51e-5)" "unprognostic (1.88e-1)" "potential prognostic unfavorable (1.17e-5)" "potential prognostic favorable (1.42e-4)" "unprognostic (1.10e-1)" "unprognostic (6.73e-2)" "unprognostic (1.01e-3)" "unprognostic (1.42e-2)" "unprognostic (4.60e-2)" "unprognostic (3.66e-2)" "potential prognostic unfavorable (2.29e-4)" "unprognostic (1.70e-1)" "unprognostic (1.00e-1)" "unprognostic (3.03e-2)" "potential prognostic unfavorable (4.32e-4)" "unprognostic (2.31e-2)" "unprognostic (7.72e-2)" "potential prognostic favorable (2.68e-5)" "unprognostic (2.81e-1)" "unprognostic (7.08e-2)" "unprognostic (4.35e-2)" "unprognostic (1.48e-1)" "unprognostic (1.48e-1)" "unprognostic (1.34e-1)" TRIM50 "FLJ32804, TRIM50A" ENSG00000146755 "Tripartite motif containing 50" Q86XT4 7 73312536-73328082 "Enzymes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "pancreas: 28.0;parathyroid gland: 31.1;stomach 1: 46.0" "Group enriched" "Detected in some" 5 "Distal convoluted tubule cells: 106.4;Granulosa cells: 44.6;Parietal cells: 86.6" "Cell type enhanced" "Detected in single" "central nervous system macrophage: 1.5" "Cancer enriched" "Detected in some" 24 "Kidney Chromophobe (TCGA): 117.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "Gastric cancer: 1.1;liver cancer: 1.7" "Adrenal gland - Macrophages, Stomach - Parietal cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA019862, HPA047843" Uncertain Approved Cytosol NA NA "Cluster 70: Non-specific - Protein processing" "Cluster 18: Liver cancer - Metabolism" "Cluster 97: Non-specific - Cellular respiration" 46 Cytosol "HPA019862: , HPA047843: " "unprognostic (5.76e-2)" "unprognostic (6.74e-2)" "unprognostic (2.20e-3)" "unprognostic (1.07e-1)" "unprognostic (3.65e-2)" TRIM51 "SPRYD5, TRIM51A" ENSG00000124900 "Tripartite motif-containing 51" Q9BSJ1 11 55883297-55891810 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 44 "Skin Cutaneous Melanoma (TCGA): 8.3" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 113 "basophil: 11.2" "Lineage enriched" "Detected in single" 113 "granulocytes: 11.2" "Cancer enriched" "Detected in single" 22 "skin cancer: 11.0" "Testis - Spermatogonia" "HPA044988, HPA077883" Uncertain Approved Nucleoli,Vesicles NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 69: Skin cancer - ECM organization" "Cluster 106: Spermatogonia - Spermatogonial differentiation" Vesicles Nucleoli "HPA044988: , HPA077883: " "unprognostic (8.63e-2)" TRIM51G TRIM51GP ENSG00000220948 "Tripartite motif-containing 51G" A0A3B3IT33 11 48975498-48983885 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA044988, HPA077883" Uncertain Approved Nucleoli,Vesicles NA NA "Cluster 1: Neuronal - Visual perception" Vesicles Nucleoli "HPA044988: , HPA077883: " TRIM52 RNF102 ENSG00000183718 "Tripartite motif containing 52" Q96A61 5 181254077-181261150 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "HPA054565, HPA056819" Approved Approved "Nucleoli,Intermediate filaments" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 40: Non-specific - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 7: Non-specific - Transcription" 5 Nucleoli "Intermediate filaments" "HPA054565: , HPA056819: " "potential prognostic favorable (3.90e-4)" "unprognostic (1.07e-1)" "unprognostic (1.77e-1)" "unprognostic (2.50e-1)" "unprognostic (6.30e-3)" "unprognostic (1.35e-1)" "unprognostic (2.95e-1)" "unprognostic (1.73e-1)" "unprognostic (1.45e-1)" "unprognostic (1.01e-1)" "unprognostic (3.03e-2)" "unprognostic (1.77e-2)" "unprognostic (1.36e-1)" "potential prognostic unfavorable (9.20e-4)" "unprognostic (3.32e-2)" "unprognostic (2.52e-2)" "unprognostic (2.68e-1)" "unprognostic (1.24e-1)" "unprognostic (1.67e-2)" "unprognostic (1.30e-1)" "unprognostic (1.02e-1)" "unprognostic (1.55e-3)" "unprognostic (2.75e-3)" "unprognostic (3.47e-2)" "unprognostic (5.32e-2)" "unprognostic (2.50e-2)" "unprognostic (1.86e-1)" "unprognostic (2.89e-1)" "unprognostic (3.54e-2)" "unprognostic (7.82e-3)" "unprognostic (3.27e-1)" TRIM54 "MURF, MURF-3, RNF30" ENSG00000138100 "Tripartite motif containing 54" Q9BYV2 2 27282429-27307439 "Predicted intracellular proteins" Differentiation "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 14 "heart muscle: 205.1;skeletal muscle: 570.0;tongue: 165.5" "Cell type enriched" "Detected in some" 4 "Myonuclei: 980.5" "Cell type enhanced" "Detected in many" "amygdala excitatory: 21.6;deep-layer intratelencephalic: 25.0;hippocampal dentate gyrus: 37.3;upper-layer intratelencephalic: 33.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 11.5" "Immune cell enriched" "Detected in single" 17 "NK-cell: 3.6" "Lineage enriched" "Detected in single" 17 "NK-cells: 3.6" "Cancer enhanced" "Detected in some" "Gastric cancer: 2.5" "Adipose visceral - Smooth muscle cells, Heart muscle - Cardiomyocytes, Kidney - Podocytes, Spleen - Fibroblasts_2" "Region enhanced" "Detected in some" "amygdala: 3.1" HPA019690 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 53: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 55: Myocytes - Oxidative muscle function" 162 "Plasma membrane, Cytosol" "HPA019690: " "unprognostic (1.90e-1)" "potential prognostic favorable (5.91e-4)" "unprognostic (2.21e-1)" "unprognostic (9.65e-2)" "unprognostic (4.46e-3)" "unprognostic (1.21e-2)" "unprognostic (4.92e-2)" "potential prognostic unfavorable (1.53e-7)" "unprognostic (1.07e-1)" "unprognostic (5.59e-3)" "unprognostic (1.79e-3)" "unprognostic (2.20e-2)" "unprognostic (1.12e-1)" "unprognostic (3.22e-2)" "unprognostic (2.02e-2)" "unprognostic (1.75e-1)" "unprognostic (2.11e-1)" TRIM55 "MURF-2, RNF29" ENSG00000147573 "Tripartite motif containing 55" Q9BYV6 8 66126896-66175485 "Predicted intracellular proteins, Predicted membrane proteins" "Muscle protein, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "heart muscle: 57.8;liver: 35.5;skeletal muscle: 27.7;tongue: 31.4" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 151.5;Endometrial ciliated cells: 289.3;Epididymal efferent duct absorptive cells: 77.5;Epididymal efferent duct ciliated cells: 429.8;Epididymal principal cells: 87.2;Fallopian tube ciliated cells: 69.2;Hepatocytes: 64.5;Myonuclei: 215.3;Myosatellite cells: 61.0;Thymic myoid cells: 134.6" "Group enriched" "Detected in some" 4 "ependymal cell: 9.8;upper rhombic lip: 11.8" "Group enriched" "Detected in some" 10 "Kidney Renal Clear Cell Carcinoma (TCGA): 12.5;Kidney Renal Papillary Cell Carcinoma (TCGA): 6.7;Liver Hepatocellular Carcinoma (TCGA): 15.9" "Region enhanced" "Detected in some" "cerebellum: 3.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Kidney cancer: 39.2;Rhabdoid: 58.1;testis cancer: 83.9" "Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Pituitary gland - Gonadotropes, Skin - Sebaceous gland cells, Spleen - Plasma cells, Testis - Early spermatids" "Not detected" "Not detected" "Region enhanced" "Detected in single" "pons: 1.1" "HPA038793, HPA053691" Approved Approved "Golgi apparatus,Cytosol" NA NA "Cluster 41: Striated muscle - Muscle contraction" "Cluster 2: Neurons - Nucleosome" "Cluster 5: Rhabdoid - Unknown function" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 22 "Golgi apparatus" Cytosol "HPA038793: , HPA053691: " "unprognostic (3.65e-2)" "unprognostic (1.01e-1)" "potential prognostic favorable (4.39e-6)" "unprognostic (3.64e-2)" "potential prognostic favorable (7.04e-5)" "unprognostic (1.81e-3)" "unprognostic (4.54e-2)" "unprognostic (1.40e-1)" "unprognostic (1.53e-1)" TRIM56 RNF109 ENSG00000169871 "Tripartite motif containing 56" Q9BRZ2 7 101085481-101097967 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 73.5;endothelial cell: 98.2;leukocyte: 99.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024358 Approved Uncertain Nucleoplasm,Cytosol NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 18: Non-specific - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 18 Nucleoplasm Cytosol "HPA024358: " "unprognostic (4.96e-3)" "unprognostic (2.26e-1)" "unprognostic (4.65e-1)" "unprognostic (1.55e-2)" "unprognostic (7.53e-3)" "unprognostic (5.16e-3)" "unprognostic (5.70e-2)" "potential prognostic unfavorable (3.91e-5)" "unprognostic (1.80e-2)" "unprognostic (1.64e-2)" "unprognostic (5.86e-3)" "potential prognostic favorable (7.28e-6)" "unprognostic (3.35e-2)" "potential prognostic unfavorable (1.16e-5)" "unprognostic (1.96e-1)" "unprognostic (2.73e-1)" "unprognostic (1.35e-1)" "unprognostic (2.75e-1)" "unprognostic (1.53e-1)" "unprognostic (7.99e-2)" "unprognostic (1.59e-2)" "unprognostic (1.31e-1)" "potential prognostic unfavorable (9.86e-5)" "unprognostic (1.48e-1)" "unprognostic (2.09e-2)" "unprognostic (3.78e-2)" "unprognostic (6.73e-2)" "unprognostic (8.94e-2)" "unprognostic (1.82e-1)" "unprognostic (2.70e-2)" "unprognostic (1.39e-1)" TRIM58 BIA2 ENSG00000162722 "Tripartite motif containing 58" Q8NG06 1 247857187-247880138 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 30.3;thyroid gland: 14.2" "Group enriched" "Detected in many" 7 "Erythrocytes: 477.6;Platelets: 1454.7" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 7.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 40.8" "Liver - Erythroid cells, Prostate - Prostate glandular cells, Spleen - Erythrocytes, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA023637 Uncertain NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 15: Bone marrow - Innate immune response" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 47: Leukemia - Hemostasis" "Cluster 47: Platelets - Hemostasis" 4 "HPA023637: " "unprognostic (4.45e-1)" "unprognostic (1.85e-1)" "unprognostic (3.58e-1)" "potential prognostic favorable (8.14e-4)" "unprognostic (2.76e-2)" "unprognostic (1.60e-2)" "unprognostic (3.11e-1)" "unprognostic (2.20e-1)" "unprognostic (3.71e-3)" "unprognostic (2.39e-1)" "unprognostic (4.06e-1)" "unprognostic (1.59e-1)" "unprognostic (1.38e-2)" "unprognostic (4.76e-2)" TRIM59 "Mrf1, RNF104, TRIM57, TSBF1" ENSG00000213186 "Tripartite motif containing 59" Q8IWR1 3 160432445-160485773 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 16.3;lymphoid tissue: 12.7" "Cell type enriched" "Detected in many" 20 "Oligodendrocytes: 390.1" "Cell type enriched" "Detected in all" 6 "oligodendrocyte: 479.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017750 Uncertain NA Yes "Cluster 5: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 11: White matter - Signal transduction" "Cluster 15: Kidney cancer - Membrane components" "Cluster 80: Oligodendrocytes - Myelination" 26 "HPA017750: " "unprognostic (6.80e-2)" "unprognostic (5.01e-2)" "unprognostic (2.92e-1)" "unprognostic (2.07e-2)" "unprognostic (9.09e-2)" "unprognostic (2.82e-2)" "unprognostic (4.66e-2)" "unprognostic (9.52e-3)" "unprognostic (9.85e-2)" "unprognostic (1.32e-3)" "unprognostic (1.62e-2)" "unprognostic (1.55e-1)" "unprognostic (5.11e-3)" "unprognostic (1.26e-3)" "unprognostic (7.20e-2)" "validated prognostic unfavorable (7.02e-4)" "validated prognostic unfavorable (2.70e-4)" "unprognostic (7.77e-2)" "unprognostic (7.14e-2)" "unprognostic (2.75e-1)" "unprognostic (5.85e-2)" "potential prognostic unfavorable (3.24e-4)" "unprognostic (8.35e-2)" "unprognostic (2.29e-3)" "unprognostic (8.05e-2)" "unprognostic (9.18e-2)" "unprognostic (1.58e-1)" "unprognostic (1.23e-1)" "unprognostic (3.17e-1)" "unprognostic (1.85e-1)" "unprognostic (4.45e-2)" TRIM6 RNF89 ENSG00000121236 "Tripartite motif containing 6" Q9C030 11 5596109-5612958 "Enzymes, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 19.5" "Cell type enhanced" "Detected in some" "Astrocytes: 1.2;Ependymal cells: 1.6;Epicardial cells: 2.3;Late primary spermatocytes: 1.3;Microglia: 3.5" "Cell type enhanced" "Detected in many" "deep-layer near-projecting: 9.2;fibroblast: 9.1;pericyte: 7.7" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 19.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.2" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 41.3" "Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Spleen - Macrophages, Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA060514 Uncertain NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 72: Kidney - Transmembrane transport" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 22: Non-specific - Basic cellular functions" 10 "HPA060514: " "unprognostic (3.48e-2)" "unprognostic (5.94e-2)" "unprognostic (1.44e-1)" "unprognostic (2.26e-3)" "unprognostic (6.80e-2)" "unprognostic (2.32e-2)" "potential prognostic unfavorable (1.78e-4)" "unprognostic (3.16e-2)" "potential prognostic favorable (8.23e-7)" "unprognostic (7.63e-3)" "unprognostic (2.91e-1)" "unprognostic (2.94e-1)" "validated prognostic unfavorable (1.88e-5)" "validated prognostic unfavorable (1.41e-6)" "unprognostic (3.89e-2)" "unprognostic (1.98e-2)" "unprognostic (2.96e-2)" "unprognostic (4.05e-2)" "unprognostic (7.92e-3)" "potential prognostic unfavorable (1.78e-4)" "unprognostic (2.47e-1)" "unprognostic (1.21e-1)" "unprognostic (1.25e-1)" "unprognostic (3.01e-3)" "unprognostic (2.75e-1)" "unprognostic (3.18e-2)" "unprognostic (4.63e-2)" TRIM6-TRIM34 ENSG00000258588 "TRIM6-TRIM34 readthrough" 11 5596725-5644398 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Epicardial cells: 2.3;Fibro-adipogenic progenitors: 1.0;Hematopoietic stem cells: 3.4;Proximal tubule cells: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" HPA077996 Uncertain Nucleoli,Centrosome NA NA "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" Centrosome Nucleoli "HPA077996: " TRIM60 "FLJ35882, RNF129, RNF33" ENSG00000176979 "Tripartite motif containing 60" Q495X7 4 165016458-165041749 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "placenta: 1.4;testis: 1.4" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 6.1;Differentiating spermatogonia: 8.9;Early primary spermatocytes: 16.9;Extravillous trophoblasts: 10.7;Migrating cytotrophoblasts: 8.6;Oocytes: 18.4;Tuft cells: 11.5;Undifferentiated spermatogonia: 4.6" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 61 "Testicular Germ Cell Tumor (TCGA): 9.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "testis cancer: 1.5" "Testis - Spermatocytes" "Not detected" "Not detected" "HPA035809, HPA035810, HPA061496" Uncertain Uncertain Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 34: Testis cancer - Unknown function" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 1 Nucleoli "Nucleoplasm, Cytosol" "HPA035809: , HPA035810: , HPA061496: " "unprognostic (1.66e-1)" TRIM61 RNF35 ENSG00000183439 "Tripartite motif containing 61" Q5EBN2 4 164954446-164977668 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Cardiomyocytes: 78.2;Late primary spermatocytes: 142.8" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 9.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "testis cancer: 9.4" "Testis - Early spermatids" "Not detected" "Not detected" HPA049109 Uncertain Approved "Nucleoli fibrillar center,Endoplasmic reticulum" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 61: Non-specific - Transcription" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" "Nucleoli fibrillar center, Endoplasmic reticulum" "HPA049109: " "unprognostic (8.59e-2)" "unprognostic (1.82e-1)" "unprognostic (7.55e-2)" "unprognostic (3.00e-2)" "unprognostic (4.00e-2)" "unprognostic (4.19e-2)" "unprognostic (2.35e-1)" "unprognostic (8.13e-2)" "unprognostic (3.29e-2)" "unprognostic (2.81e-2)" "unprognostic (2.81e-3)" "unprognostic (1.06e-1)" "unprognostic (4.35e-2)" "unprognostic (1.18e-1)" "unprognostic (7.07e-2)" "unprognostic (1.89e-2)" "unprognostic (3.32e-3)" "unprognostic (3.26e-1)" "unprognostic (2.33e-1)" "unprognostic (2.08e-1)" TRIM62 "DEAR1, FLJ10759" ENSG00000116525 "Tripartite motif containing 62" Q9BVG3 1 33145399-33182059 "Enzymes, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gonadotrophs: 38.0;Oligodendrocyte progenitor cells: 61.0;Oligodendrocytes: 44.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050061 Approved "Vesicles,Focal adhesion sites" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 2: Non-specific - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 11: Neuronal - Sensory perception" "Cluster 22: Non-specific - Basic cellular functions" 18 "Vesicles, Focal adhesion sites" "HPA050061: " "unprognostic (2.34e-2)" "unprognostic (5.67e-2)" "unprognostic (2.05e-1)" "unprognostic (1.58e-1)" "unprognostic (5.67e-2)" "unprognostic (9.11e-2)" "unprognostic (2.14e-2)" "potential prognostic favorable (2.34e-4)" "unprognostic (2.92e-2)" "unprognostic (2.18e-2)" "unprognostic (1.29e-1)" "unprognostic (4.77e-2)" "unprognostic (1.74e-1)" "potential prognostic unfavorable (2.47e-4)" "unprognostic (9.81e-2)" "unprognostic (1.79e-3)" "unprognostic (3.97e-2)" "unprognostic (1.15e-1)" "unprognostic (2.57e-1)" "unprognostic (7.03e-2)" "unprognostic (2.66e-2)" "unprognostic (8.46e-3)" "unprognostic (8.51e-2)" "unprognostic (2.87e-1)" "unprognostic (1.89e-1)" "unprognostic (1.80e-1)" "unprognostic (1.09e-1)" "unprognostic (2.05e-1)" "unprognostic (5.39e-2)" "unprognostic (3.76e-2)" "unprognostic (3.83e-2)" TRIM63 "IRF, MURF-1, RNF28, SMRZ" ENSG00000158022 "Tripartite motif containing 63" Q969Q1 1 26051301-26068436 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Muscle protein, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skeletal muscle: 1847.0" "Cell type enriched" "Detected in some" 4 "Thymic myoid cells: 630.9" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Skin Cutaneous Melanoma (TCGA): 68.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 45 "skin cancer: 36.2" "Adipose subcutaneous - Mast cells, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebellum: 7.1" NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 54 "unprognostic (9.72e-3)" "validated prognostic favorable (8.96e-5)" "validated prognostic favorable (8.73e-4)" "unprognostic (9.95e-2)" "unprognostic (1.49e-1)" "unprognostic (4.67e-1)" "unprognostic (1.51e-1)" TRIM64 "C11orf28, TRIM64A" ENSG00000204450 "Tripartite motif containing 64" A6NGJ6 11 89966037-89974072 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 12 "placenta: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045370 Approved NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" 1 "HPA045370: " TRIM64B ENSG00000189253 "Tripartite motif containing 64B" A6NI03 11 89870438-89878487 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 34 "placenta: 3.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 839 "basophil: 83.9" "Lineage enriched" "Detected in single" 839 "granulocytes: 83.9" "Not detected" "Not detected" "Skin - Inner root sheath cells" HPA045370 Approved NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" "HPA045370: " TRIM64C ENSG00000214891 "Tripartite motif containing 64C" A6NLI5 11 49053714-49059112 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 22 "Epicardial cells: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045370 Uncertain NA NA "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" "HPA045370: " TRIM65 ENSG00000141569 "Tripartite motif containing 65" Q6PJ69 17 75880335-75896951 "Predicted intracellular proteins" "Immunity, Innate immunity" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021575, HPA021578, HPA064820" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 27: Breast cancer - Unknown function" "Cluster 7: Non-specific - Transcription" 10 "Nucleoplasm, Cytosol" Vesicles "HPA021575: , HPA021578: , HPA064820: " "unprognostic (2.41e-1)" "unprognostic (1.54e-1)" "unprognostic (6.17e-2)" "unprognostic (1.68e-2)" "unprognostic (7.54e-2)" "unprognostic (4.75e-2)" "unprognostic (1.32e-1)" "unprognostic (2.95e-1)" "unprognostic (5.61e-3)" "unprognostic (1.47e-2)" "unprognostic (3.59e-2)" "unprognostic (4.73e-1)" "unprognostic (2.75e-2)" "potential prognostic unfavorable (1.63e-6)" "unprognostic (1.23e-2)" "unprognostic (2.58e-1)" "unprognostic (1.49e-2)" "unprognostic (9.03e-2)" "unprognostic (1.79e-1)" "unprognostic (3.88e-1)" "unprognostic (1.16e-1)" "unprognostic (7.79e-2)" "unprognostic (9.10e-2)" "potential prognostic unfavorable (1.95e-4)" "unprognostic (9.15e-3)" "unprognostic (1.49e-2)" "unprognostic (2.42e-1)" "unprognostic (2.55e-3)" "unprognostic (1.77e-1)" "unprognostic (5.19e-2)" "unprognostic (2.40e-2)" TRIM66 "C11orf29, KIAA0298, TIF1D" ENSG00000166436 "Tripartite motif containing 66" 11 8612037-8682694 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 13.0" "Cell type enhanced" "Detected in many" "Early spermatids: 193.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027420 Approved Supported Nucleoplasm NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 33: Neurons - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" Nucleoplasm "HPA027420: " "unprognostic (7.06e-2)" "unprognostic (8.92e-2)" "unprognostic (5.27e-3)" "unprognostic (3.90e-2)" "unprognostic (9.57e-2)" "unprognostic (5.60e-2)" "unprognostic (6.30e-2)" "unprognostic (2.75e-1)" "unprognostic (1.40e-3)" "unprognostic (2.69e-1)" "unprognostic (1.73e-2)" "unprognostic (2.17e-2)" "potential prognostic favorable (7.35e-5)" "unprognostic (1.07e-1)" "unprognostic (7.39e-3)" "unprognostic (8.87e-2)" "unprognostic (6.55e-2)" "unprognostic (2.08e-1)" "unprognostic (2.18e-1)" "unprognostic (4.51e-2)" "unprognostic (2.34e-2)" "unprognostic (5.81e-2)" "unprognostic (5.72e-3)" "unprognostic (2.14e-1)" "unprognostic (2.68e-3)" "unprognostic (7.18e-3)" "unprognostic (7.35e-2)" "unprognostic (8.50e-2)" "unprognostic (2.99e-1)" "unprognostic (3.63e-2)" "unprognostic (3.23e-1)" TRIM67 TNL ENSG00000119283 "Tripartite motif containing 67" Q6ZTA4 1 231162058-231221565 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "brain: 8.3;retina: 3.1" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 10.6;Brain excitatory neurons: 13.0;Brain inhibitory neurons: 20.5;Oligodendrocyte progenitor cells: 25.7;Other brain neurons: 11.7;Retinal amacrine cells: 50.6;Retinal bipolar cells: 21.5;Retinal horizontal cells: 92.2" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 113.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "Neuroblastoma: 7.6" "Colon - Colon enteroendocrine cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA034776 Uncertain NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 35: Non-specific - DNA binding" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 10 "HPA034776: " "unprognostic (3.19e-1)" "potential prognostic favorable (2.94e-4)" TRIM68 "FLJ10369, RNF137, SS-56" ENSG00000167333 "Tripartite motif containing 68" Q6AZZ1 11 4598672-4608231 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Respiratory secretory cells: 14.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023455 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 33: Thyroid gland - Tissue development" "Cluster 55: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" 27 "Nucleoplasm, Cytosol" "HPA023455: " "unprognostic (1.13e-3)" "unprognostic (7.89e-2)" "unprognostic (7.99e-2)" "unprognostic (3.67e-3)" "unprognostic (1.37e-1)" "potential prognostic favorable (2.98e-4)" "unprognostic (2.96e-3)" "unprognostic (3.62e-2)" "unprognostic (8.10e-2)" "unprognostic (5.83e-2)" "potential prognostic favorable (7.46e-4)" "unprognostic (1.07e-2)" "unprognostic (6.51e-3)" "unprognostic (6.75e-2)" "unprognostic (9.55e-2)" "unprognostic (3.53e-2)" "unprognostic (3.54e-1)" "unprognostic (1.13e-2)" "unprognostic (2.47e-1)" "unprognostic (5.64e-2)" "unprognostic (6.72e-2)" "unprognostic (3.19e-2)" "unprognostic (1.44e-1)" "unprognostic (8.60e-2)" "unprognostic (2.58e-2)" "potential prognostic unfavorable (1.30e-4)" "unprognostic (8.49e-2)" "unprognostic (3.82e-2)" "unprognostic (1.65e-1)" "unprognostic (3.00e-1)" "unprognostic (2.60e-1)" TRIM69 "RNF36, Trif, TRIMLESS" ENSG00000185880 "Tripartite motif containing 69" Q86WT6 15 44728988-44767829 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 33.7" "Cell type enhanced" "Detected in many" "Astrocytes: 24.3;Bergmann glia: 15.8;Brain excitatory neurons: 28.3;Brain inhibitory neurons: 29.8;Choroid plexus epithelial cells: 26.4;Oligodendrocyte progenitor cells: 21.0;Other brain neurons: 27.8;Podocytes: 12.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 4.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "T-reg: 4.3" "Lineage enriched" "Detected in single" 7 "T-cells: 4.3" "Cancer enhanced" "Detected in some" "lymphoma: 1.6;Myeloma: 2.2" "Prostate - Fibroblasts, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA028894 Enhanced NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 67: Testis - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 109: Neurons - Neuronal signaling" 27 "HPA028894: " "unprognostic (4.07e-2)" "potential prognostic favorable (2.32e-4)" "unprognostic (2.84e-2)" "unprognostic (1.79e-1)" "unprognostic (1.42e-1)" "unprognostic (1.55e-1)" "unprognostic (2.07e-3)" "unprognostic (1.19e-2)" "unprognostic (6.73e-2)" "unprognostic (7.65e-3)" "unprognostic (6.76e-2)" TRIM7 "GNIP, RNF90" ENSG00000146054 "Tripartite motif containing 7" Q9C029 5 181193924-181205293 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Antiviral defense, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 52.4;skeletal muscle: 181.0;tongue: 47.8" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 157.6;Esophageal basal cells: 101.3;Esophageal suprabasal cells: 154.5;Myonuclei: 175.3;Respiratory basal cells: 53.2;Respiratory deuterosomal cells: 40.4;Respiratory secretory cells: 52.9;Suprabasal keratinocytes: 71.7" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 22.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Minor salivary gland basal cells, Skeletal muscle - Skeletal myocytes, Skin - Keratinocyte (other)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA039213 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 2: Neurons - Nucleosome" "Cluster 7: Liver cancer - Metabolism" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 31 Vesicles "Nucleoplasm, Cytosol" "HPA039213: " "unprognostic (6.54e-2)" "unprognostic (1.97e-1)" "unprognostic (2.30e-2)" "unprognostic (2.25e-1)" "unprognostic (9.14e-2)" "unprognostic (7.44e-3)" "unprognostic (1.27e-2)" "unprognostic (7.14e-2)" "unprognostic (1.16e-1)" "potential prognostic favorable (8.71e-4)" "unprognostic (5.33e-2)" "unprognostic (1.85e-2)" "unprognostic (5.62e-2)" "potential prognostic unfavorable (3.04e-6)" "unprognostic (7.12e-2)" "unprognostic (1.40e-1)" "unprognostic (1.53e-1)" "unprognostic (1.88e-1)" "unprognostic (3.86e-1)" "unprognostic (2.51e-1)" "unprognostic (4.21e-3)" "unprognostic (1.16e-1)" "unprognostic (2.16e-1)" "unprognostic (1.49e-1)" "unprognostic (2.58e-2)" TRIM71 "LIN-41, LIN41" ENSG00000206557 "Tripartite motif containing 71" Q2Q1W2 3 32817997-32897824 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "RNA-mediated gene silencing, Ubl conjugation pathway" "Developmental protein, RNA-binding, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 5 "testis: 4.5" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 18.0;Alveolar cells type 2: 14.4;Brain inhibitory neurons: 15.7;Differentiating spermatogonia: 18.7;Distal convoluted tubule cells: 23.0;Extravillous trophoblasts: 25.3;Migrating cytotrophoblasts: 13.4;Proximal tubule cells: 42.9;Respiratory ciliated cells: 12.4;Retinal amacrine cells: 33.2;Retinal pigment epithelial cells: 12.8;Thymocytes: 20.3;Transitional alveolar cells: 18.0;Undifferentiated spermatogonia: 43.6" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in some" 35 "Testicular Germ Cell Tumor (TCGA): 40.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "testis cancer: 70.3" "Adipose visceral - Mesothelial cells, Kidney - Proximal tubular cells, Lung - Alveolar cells type 2, Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA038141, HPA038142" Uncertain Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 67: Testis - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 7 "Plasma membrane, Actin filaments, Focal adhesion sites" "HPA038141: , HPA038142: " "unprognostic (1.15e-1)" "unprognostic (9.44e-3)" "unprognostic (8.51e-2)" TRIM72 MG53 ENSG00000177238 "Tripartite motif containing 72" Q6ZMU5 16 31214091-31231537 "Predicted intracellular proteins, Transporters" "Exocytosis, Transport, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "skeletal muscle: 142.2;tongue: 40.2" "Group enriched" "Detected in many" 4 "Myonuclei: 232.6;Thymic myoid cells: 263.8" "Cell type enriched" "Detected in some" 4 "upper rhombic lip: 12.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in some" "Myeloma: 12.1;Sarcoma: 8.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA054909 Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 35: Non-specific - DNA binding" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 17 Vesicles Nucleoplasm "HPA054909: " "unprognostic (2.55e-1)" "unprognostic (6.81e-2)" "unprognostic (8.16e-2)" "unprognostic (1.18e-1)" "unprognostic (3.92e-2)" "unprognostic (4.66e-1)" "unprognostic (1.95e-1)" "unprognostic (9.78e-3)" "unprognostic (2.71e-1)" "unprognostic (5.49e-2)" "unprognostic (8.69e-2)" "unprognostic (3.76e-2)" "unprognostic (4.85e-2)" "unprognostic (2.02e-1)" "unprognostic (7.83e-2)" TRIM73 TRIM50B ENSG00000178809 "Tripartite motif containing 73" Q86UV7 7 75395063-75410996 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 7.9;Distal convoluted tubule cells: 27.3;Loop of henle epithelial cells: 21.6;Papillary tip epithelial cells: 13.5;Parietal cells: 35.4;Podocytes: 13.7;Proximal tubule cells: 21.9;Renal collecting duct intercalated cells: 42.1;Renal collecting duct principal cells: 20.1;Renal connecting tubule cells: 19.4" "Low cell type specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Stomach - Parietal cells" "HPA047843, HPA051845" Uncertain Uncertain Cytosol NA NA "Cluster 60: Stomach - Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 105: Non-specific - Mixed function" Cytosol "HPA047843: , HPA051845: " "unprognostic (4.29e-2)" "unprognostic (1.78e-2)" "potential prognostic favorable (6.08e-5)" "unprognostic (1.78e-2)" "unprognostic (1.01e-1)" "unprognostic (2.22e-2)" "unprognostic (2.63e-1)" "potential prognostic unfavorable (8.94e-6)" "unprognostic (1.79e-3)" "unprognostic (3.69e-2)" "potential prognostic favorable (1.00e-4)" "unprognostic (1.61e-3)" "unprognostic (8.31e-2)" "unprognostic (3.07e-1)" "unprognostic (8.29e-2)" "unprognostic (8.16e-3)" "unprognostic (5.23e-3)" "unprognostic (2.30e-3)" "unprognostic (2.27e-2)" "unprognostic (7.37e-2)" "unprognostic (2.20e-1)" "unprognostic (3.84e-2)" TRIM74 "MGC45440, TRIM50C" ENSG00000155428 "Tripartite motif containing 74" Q86UV6 7 72959485-72969466 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 10.6;testis: 6.5" "Cell type enriched" "Detected in some" 7 "Parietal cells: 33.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Stomach - Parietal cells" HPA047843 Approved Cytosol NA NA "Cluster 21: Testis - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 6: Leukemia - Signal transduction" "Cluster 97: Non-specific - Cellular respiration" Cytosol "HPA047843: " "unprognostic (6.54e-2)" "unprognostic (8.86e-3)" "unprognostic (3.76e-1)" "unprognostic (1.17e-1)" "unprognostic (3.62e-2)" "unprognostic (2.11e-1)" TRIM75 TRIM75P ENSG00000250374 "Tripartite motif containing 75" A6NK02 4 165053866-165060554 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Epicardial cells: 4.5;Thymic myoid cells: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 34: Testis cancer - Unknown function" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" TRIM77 TRIM77P ENSG00000214414 "Tripartite motif containing 77" I1YAP6 11 89710299-89717872 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 22 "Oocytes: 13.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA039896 Uncertain NA NA "Cluster 41: Oocytes - Oogenesis" "HPA039896: " TRIM8 "GERP, RNF27" ENSG00000171206 "Tripartite motif containing 8" Q9BZR9 10 102644479-102658318 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023560, HPA023561" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 24: Non-specific - Transcription" "Cluster 19: Astrocytes - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 36 Nucleoplasm "Vesicles, Cytosol" "HPA023560: , HPA023561: " "unprognostic (2.87e-2)" "unprognostic (2.60e-2)" "unprognostic (1.89e-1)" "unprognostic (2.14e-1)" "unprognostic (9.95e-2)" "unprognostic (5.26e-3)" "unprognostic (2.54e-1)" "unprognostic (1.63e-2)" "unprognostic (1.81e-1)" "potential prognostic favorable (2.47e-5)" "unprognostic (2.66e-2)" "unprognostic (2.55e-1)" "unprognostic (4.31e-1)" "unprognostic (1.23e-1)" "unprognostic (3.55e-1)" "unprognostic (1.85e-1)" "unprognostic (1.52e-1)" "unprognostic (2.32e-3)" "unprognostic (2.81e-2)" "unprognostic (1.12e-2)" "unprognostic (2.37e-2)" "unprognostic (5.35e-2)" "unprognostic (4.62e-2)" "unprognostic (9.39e-2)" "unprognostic (7.99e-2)" "unprognostic (3.33e-2)" "unprognostic (3.36e-2)" "unprognostic (1.06e-1)" "unprognostic (1.24e-1)" "unprognostic (6.45e-2)" "unprognostic (3.13e-1)" TRIM9 "RNF91, SPRING" ENSG00000100505 "Tripartite motif containing 9" Q9C026 14 50975262-51096061 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 46.3;retina: 21.5" "Cell type enhanced" "Detected in many" "Astrocytes: 498.6;Bergmann glia: 492.8;Brain excitatory neurons: 594.2;Brain inhibitory neurons: 479.7;Lactotrophs: 169.3;Oligodendrocyte progenitor cells: 805.0;Oligodendrocytes: 204.0;Other brain neurons: 187.9;Pituicytes/FSCs: 660.3;Pituitary stem cells: 266.9;Retinal amacrine cells: 251.3" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 8 "Glioblastoma Multiforme (TCGA): 71.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal medulla cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 15: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" 28 "unprognostic (8.25e-2)" "unprognostic (9.56e-2)" "unprognostic (3.33e-2)" "unprognostic (4.98e-2)" "unprognostic (2.44e-2)" "unprognostic (9.19e-2)" "potential prognostic favorable (2.15e-4)" "unprognostic (4.61e-2)" "unprognostic (8.92e-2)" "unprognostic (3.78e-2)" "unprognostic (8.32e-2)" "unprognostic (4.24e-2)" "unprognostic (2.23e-1)" "unprognostic (1.22e-2)" "unprognostic (9.64e-2)" "unprognostic (2.44e-2)" "unprognostic (1.05e-1)" TRIML1 "FLJ36180, RNF209" ENSG00000184108 "Tripartite motif family like 1" Q8N9V2 4 188139441-188147743 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Developmental protein, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 110 "testis: 11.0" "Cell type enriched" "Detected in some" 4 "Early spermatids: 189.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 34: Testis cancer - Unknown function" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 1 TRIML2 "FLJ25801, SPRYD6" ENSG00000179046 "Tripartite motif family like 2" Q8N7C3 4 188091272-188109603 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "placenta: 3.8;testis: 2.4" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 20.4;Differentiating spermatogonia: 5.9;Early primary spermatocytes: 23.8;Early spermatids: 25.6;Extravillous trophoblasts: 10.4;Late spermatids: 5.9;Migrating cytotrophoblasts: 24.2;Ocular epithelial cells: 12.8;Syncytiotrophoblasts: 15.4;Undifferentiated spermatogonia: 4.5" "Cell type enhanced" "Detected in single" "medium spiny neuron: 1.1" "Cancer enriched" "Detected in some" 37 "Testicular Germ Cell Tumor (TCGA): 55.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 10 "testis cancer: 133.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA043838 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 69: Skin cancer - ECM organization" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 45 "Plasma membrane, Cytosol" "HPA043838: " "potential prognostic unfavorable (8.72e-7)" "unprognostic (2.47e-1)" TRIO ARHGEF23 ENSG00000038382 "Trio Rho guanine nucleotide exchange factor" O75962 5 14143342-14532128 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Guanine-nucleotide releasing factor, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 1.4;NK-cell: 1.4" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008157, HPA064664" Supported Supported "Vesicles,Plasma membrane,Primary cilium,Primary cilium tip,Basal body,Cytosol" No No "Cluster 24: Non-specific - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 29: Non-specific - Unknown function" "Cluster 51: Secretory epithelial cells - Mixed function" 13 Cytosol "Vesicles, Plasma membrane, Primary cilium, Primary cilium tip, Basal body" "HPA008157: , HPA064664: " "unprognostic (3.12e-1)" "unprognostic (1.72e-1)" "unprognostic (1.47e-1)" "unprognostic (1.75e-2)" "unprognostic (1.72e-1)" "unprognostic (2.32e-2)" "unprognostic (3.05e-2)" "unprognostic (1.00e-1)" "unprognostic (9.19e-2)" "unprognostic (2.41e-1)" "potential prognostic unfavorable (5.10e-6)" "unprognostic (7.71e-3)" "unprognostic (1.63e-1)" "potential prognostic unfavorable (7.86e-5)" "unprognostic (3.62e-1)" "unprognostic (1.70e-1)" "unprognostic (1.16e-2)" "unprognostic (2.80e-1)" "unprognostic (3.20e-2)" "unprognostic (2.53e-1)" "unprognostic (3.11e-2)" "unprognostic (4.31e-1)" "unprognostic (1.75e-3)" "unprognostic (2.08e-1)" "unprognostic (1.16e-1)" "potential prognostic favorable (7.28e-4)" "unprognostic (4.23e-3)" "unprognostic (9.46e-3)" "unprognostic (2.95e-1)" "potential prognostic unfavorable (1.55e-4)" "potential prognostic unfavorable (2.58e-4)" TRIOBP "DFNB28, HRIHFB2122, KIAA1662, TAP68, Tara" ENSG00000100106 "TRIO and F-actin binding protein" Q9H2D6 22 37697048-37776556 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Actin-binding "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 340.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003747, HPA019769" Enhanced NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 35: Non-specific - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 66: Non-specific - Mitochondria" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 19 "HPA003747: , HPA019769: " "unprognostic (2.42e-2)" "unprognostic (1.52e-1)" "unprognostic (5.88e-2)" "unprognostic (1.18e-1)" "unprognostic (1.38e-1)" "unprognostic (2.44e-1)" "unprognostic (1.66e-1)" "unprognostic (6.29e-2)" "unprognostic (7.38e-3)" "unprognostic (2.44e-1)" "potential prognostic favorable (4.14e-5)" "unprognostic (1.78e-3)" "potential prognostic favorable (8.70e-4)" "unprognostic (4.73e-2)" "unprognostic (3.03e-1)" "unprognostic (1.34e-1)" "unprognostic (1.85e-1)" "unprognostic (9.11e-3)" "unprognostic (8.11e-2)" "unprognostic (1.34e-1)" "unprognostic (4.80e-1)" "unprognostic (9.19e-2)" "unprognostic (1.98e-1)" "unprognostic (4.99e-1)" "unprognostic (3.33e-2)" "unprognostic (2.16e-2)" "unprognostic (1.10e-1)" "unprognostic (3.52e-1)" "unprognostic (1.38e-1)" "unprognostic (3.89e-2)" "unprognostic (1.04e-1)" TRIP10 "CIP4, HSTP, STOT, STP" ENSG00000125733 "Thyroid hormone receptor interactor 10" Q15642 19 6737925-6751530 "Plasma proteins, Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 339.9" "Cell type enriched" "Detected in many" 10 "Esophageal apical cells: 1827.8" "Cell type enhanced" "Detected in many" "endothelial cell: 26.1;pericyte: 26.3;vascular associated smooth muscle cell: 25.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "plasmacytoid DC: 26.5" "Lineage enriched" "Detected in many" 10 "dendritic cells: 26.5" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Pituitary gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041934, HPA072625, HPA073886" Approved Supported Nucleoplasm,Vesicles NA NA 14000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 84: Apical squamous epithelium - Cornification" 26 Vesicles Nucleoplasm "HPA041934: , HPA072625: , HPA073886: " "unprognostic (8.05e-2)" "unprognostic (3.61e-1)" "unprognostic (6.36e-2)" "unprognostic (1.72e-2)" "unprognostic (1.39e-2)" "unprognostic (1.50e-1)" "unprognostic (2.29e-1)" "unprognostic (1.04e-3)" "unprognostic (8.83e-3)" "unprognostic (9.55e-2)" "unprognostic (4.35e-2)" "unprognostic (3.35e-2)" "unprognostic (2.13e-1)" "unprognostic (4.53e-3)" "unprognostic (6.53e-3)" "potential prognostic unfavorable (2.70e-4)" "unprognostic (1.12e-3)" "unprognostic (1.74e-1)" "unprognostic (3.17e-1)" "unprognostic (1.07e-1)" "unprognostic (8.13e-2)" "unprognostic (2.23e-3)" "potential prognostic unfavorable (1.30e-4)" "unprognostic (3.11e-1)" "unprognostic (2.08e-2)" "unprognostic (4.22e-2)" "unprognostic (2.06e-1)" "unprognostic (2.39e-2)" "unprognostic (7.24e-2)" "unprognostic (2.65e-1)" "unprognostic (5.77e-2)" TRIP11 "CEV14, GMAP-210, GMAP210, Trip230" ENSG00000100815 "Thyroid hormone receptor interactor 11" Q15643 14 91965991-92040896 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002570 Supported Supported "Golgi apparatus,Primary cilium" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 8: Non-specific - Secretory pathway" 20 "Golgi apparatus" "Primary cilium" "HPA002570: " "unprognostic (2.49e-1)" "unprognostic (1.47e-1)" "unprognostic (1.42e-1)" "unprognostic (5.19e-3)" "unprognostic (1.18e-1)" "unprognostic (1.18e-1)" "unprognostic (1.42e-1)" "unprognostic (1.63e-1)" "unprognostic (4.67e-2)" "potential prognostic unfavorable (3.91e-4)" "validated prognostic favorable (6.55e-6)" "validated prognostic favorable (8.11e-4)" "unprognostic (3.43e-1)" "unprognostic (1.32e-3)" "unprognostic (5.25e-2)" "unprognostic (4.44e-2)" "unprognostic (1.78e-2)" "unprognostic (6.24e-2)" "unprognostic (1.86e-1)" "unprognostic (1.56e-1)" "potential prognostic unfavorable (3.02e-4)" "unprognostic (2.92e-2)" "unprognostic (2.27e-2)" "unprognostic (1.43e-1)" "unprognostic (3.36e-2)" "unprognostic (2.28e-1)" "unprognostic (1.26e-1)" "unprognostic (2.35e-1)" "unprognostic (3.06e-1)" "unprognostic (2.24e-2)" "unprognostic (3.51e-1)" TRIP12 "KIAA0045, TRIPC, ULF" ENSG00000153827 "Thyroid hormone receptor interactor 12" Q14669 2 229763837-229923239 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Autism spectrum disorder, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 702.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036835, HPA045893" Enhanced Approved "Nuclear speckles" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 39: Testis - Nuclear processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 7: Non-specific - Transcription" 61 "Nuclear speckles" "HPA036835: , HPA045893: " "unprognostic (1.24e-1)" "unprognostic (2.73e-2)" "unprognostic (2.36e-1)" "unprognostic (3.31e-2)" "unprognostic (3.12e-1)" "unprognostic (3.36e-2)" "unprognostic (1.99e-1)" "unprognostic (2.34e-3)" "unprognostic (2.58e-1)" "unprognostic (7.98e-2)" "potential prognostic favorable (3.13e-5)" "unprognostic (4.56e-2)" "unprognostic (2.26e-2)" "potential prognostic unfavorable (5.37e-6)" "unprognostic (3.67e-2)" "potential prognostic unfavorable (1.07e-4)" "unprognostic (7.92e-3)" "unprognostic (3.70e-1)" "unprognostic (3.13e-1)" "unprognostic (5.18e-2)" "potential prognostic unfavorable (6.08e-4)" "unprognostic (2.29e-2)" "unprognostic (1.33e-2)" "unprognostic (7.31e-2)" "unprognostic (8.55e-2)" "unprognostic (2.92e-3)" "unprognostic (7.52e-2)" "unprognostic (4.72e-2)" "unprognostic (1.97e-1)" "unprognostic (2.87e-1)" "unprognostic (8.54e-2)" TRIP13 16E1BP ENSG00000071539 "Thyroid hormone receptor interactor 13" Q15645 5 892884-919357 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Meiosis, Oogenesis, Spermatogenesis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 27.9" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 65.5;Early primary spermatocytes: 115.3;Early spermatids: 153.1;Epididymal efferent duct ciliated cells: 44.9;Fallopian tube ciliated cells: 61.3;Late spermatids: 330.5;Respiratory ciliated cells: 89.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA005727, HPA053093" Enhanced Approved "Nucleoplasm,Nuclear speckles,Cytosol,Acrosome,Equatorial segment,Principal piece" NA NA 54000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 39: Testis - Nuclear processes" "Cluster 14: Neurons - Synaptic function" "Cluster 29: Non-specific - Unknown function" "Cluster 107: Ciliated cells - Cilia assembly & function" 108 "Nucleoplasm, Nuclear speckles" "Cytosol, Acrosome, Equatorial segment, Principal piece" "HPA005727: , HPA053093: " "unprognostic (2.28e-2)" "unprognostic (1.09e-2)" "unprognostic (1.30e-2)" "unprognostic (2.15e-1)" "unprognostic (1.96e-1)" "unprognostic (2.40e-1)" "unprognostic (1.37e-1)" "unprognostic (8.18e-2)" "unprognostic (1.24e-1)" "potential prognostic unfavorable (1.65e-4)" "validated prognostic unfavorable (1.72e-9)" "validated prognostic unfavorable (1.84e-7)" "potential prognostic unfavorable (9.40e-7)" "validated prognostic unfavorable (7.56e-7)" "validated prognostic unfavorable (3.29e-9)" "validated prognostic unfavorable (1.17e-4)" "validated prognostic unfavorable (5.99e-6)" "unprognostic (1.62e-1)" "unprognostic (1.09e-3)" "unprognostic (1.07e-2)" "unprognostic (1.57e-1)" "unprognostic (3.24e-2)" "potential prognostic unfavorable (1.52e-4)" "unprognostic (1.25e-2)" "unprognostic (8.41e-2)" "unprognostic (1.68e-1)" "unprognostic (3.05e-3)" "unprognostic (8.89e-2)" "unprognostic (1.46e-1)" "unprognostic (3.74e-2)" TRIP4 "ASC-1, HsT17391, ZC2HC5" ENSG00000103671 "Thyroid hormone receptor interactor 4" Q15650 15 64387748-64455303 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Cancer-related genes, Congenital muscular dystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016605, HPA050666" Approved Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 72: Kidney - Transmembrane transport" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 58: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" 44 "Nucleoplasm, Nuclear bodies" "HPA016605: , HPA050666: " "unprognostic (4.91e-2)" "unprognostic (2.66e-1)" "unprognostic (1.46e-1)" "unprognostic (1.41e-1)" "unprognostic (2.91e-1)" "unprognostic (1.40e-1)" "unprognostic (3.95e-2)" "potential prognostic unfavorable (1.27e-5)" "unprognostic (1.20e-1)" "potential prognostic unfavorable (8.16e-4)" "validated prognostic favorable (6.85e-7)" "validated prognostic favorable (3.68e-4)" "unprognostic (3.05e-3)" "unprognostic (7.67e-3)" "potential prognostic unfavorable (2.63e-4)" "unprognostic (3.74e-2)" "unprognostic (4.48e-2)" "unprognostic (2.28e-1)" "unprognostic (8.39e-2)" "unprognostic (1.38e-1)" "unprognostic (6.63e-3)" "unprognostic (6.80e-2)" "potential prognostic unfavorable (6.61e-4)" "unprognostic (7.02e-2)" "unprognostic (1.98e-1)" "unprognostic (1.96e-1)" "unprognostic (4.33e-2)" "unprognostic (1.85e-1)" "unprognostic (9.66e-2)" "unprognostic (2.63e-1)" "unprognostic (8.73e-2)" TRIP6 "MGC10556, MGC10558, MGC29959, MGC3837, MGC4423, OIP1, ZRP-1" ENSG00000087077 "Thyroid hormone receptor interactor 6" Q15654 7 100867387-100873454 "Predicted intracellular proteins" "Cell adhesion, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 165.8;Esophageal basal cells: 174.4;Esophageal suprabasal cells: 139.5;Migrating cytotrophoblasts: 172.0;Syncytiotrophoblasts: 143.2" "Cell type enhanced" "Detected in many" "astrocyte: 34.0;Bergmann glia: 35.4;pericyte: 36.6;vascular associated smooth muscle cell: 42.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046454, CAB046460, HPA052813" Approved Supported "Plasma membrane,Focal adhesion sites,Cytosol" NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 74: Non-specific - Signal transduction" "Cluster 39: Astrocytes - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 26: Keratinocytes - Keratinization" 134 "Focal adhesion sites" "Plasma membrane, Cytosol" "CAB046454: , CAB046460: , HPA052813: " "unprognostic (3.59e-2)" "unprognostic (3.13e-2)" "unprognostic (1.08e-1)" "unprognostic (6.40e-2)" "unprognostic (1.27e-2)" "unprognostic (1.10e-1)" "unprognostic (4.08e-2)" "potential prognostic unfavorable (6.45e-4)" "unprognostic (1.94e-2)" "unprognostic (6.05e-2)" "unprognostic (1.93e-2)" "unprognostic (2.26e-2)" "potential prognostic favorable (1.41e-5)" "unprognostic (1.27e-2)" "unprognostic (8.97e-2)" "unprognostic (5.02e-2)" "unprognostic (4.01e-3)" "unprognostic (1.30e-2)" "unprognostic (4.47e-2)" "unprognostic (1.03e-2)" "unprognostic (3.31e-1)" "unprognostic (7.30e-3)" "unprognostic (1.71e-1)" "unprognostic (2.06e-1)" "unprognostic (4.74e-1)" "unprognostic (1.80e-1)" "unprognostic (2.65e-1)" "unprognostic (1.16e-1)" "unprognostic (8.52e-2)" "unprognostic (2.33e-1)" "unprognostic (7.05e-2)" TRIQK "C8orf83, DKFZp779L1068, LOC286144, PRO0845" ENSG00000205133 "Triple QxxK/R motif containing" Q629K1 8 92883532-93017673 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 178.0;Neutrophil progenitors: 164.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 33.2" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Skin - Endothelial cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 76: Non-specific - Metabolism" "Cluster 55: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" "unprognostic (2.84e-2)" "unprognostic (5.57e-3)" "unprognostic (1.51e-1)" "unprognostic (4.90e-1)" "unprognostic (1.04e-1)" "unprognostic (2.97e-2)" "unprognostic (3.95e-2)" "unprognostic (2.10e-1)" "unprognostic (6.22e-3)" "potential prognostic favorable (3.35e-8)" "unprognostic (8.87e-2)" "unprognostic (5.30e-3)" "unprognostic (3.08e-1)" "unprognostic (1.73e-1)" "unprognostic (4.40e-2)" "unprognostic (1.80e-2)" "unprognostic (2.46e-2)" "unprognostic (2.86e-2)" "unprognostic (2.39e-3)" "unprognostic (5.18e-2)" "unprognostic (1.37e-1)" "unprognostic (1.35e-1)" "unprognostic (7.74e-2)" "potential prognostic unfavorable (5.03e-4)" "unprognostic (3.59e-1)" "unprognostic (8.07e-2)" "unprognostic (3.26e-1)" "unprognostic (3.87e-2)" "unprognostic (9.97e-2)" TRIR "C19orf43, fSAP18, MGC2803, TERCIR" ENSG00000123144 "Telomerase RNA component interacting RNase" Q9BQ61 19 12730640-12734684 "Predicted intracellular proteins" "Exonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 939.5;Late spermatids: 727.8;Syncytiotrophoblasts: 725.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059965 Approved Approved Nucleoplasm NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 15: Non-specific - Protein processing" 7 Nucleoplasm "HPA059965: " "unprognostic (1.74e-1)" "unprognostic (3.33e-1)" "unprognostic (1.25e-3)" "unprognostic (9.15e-3)" "unprognostic (9.47e-3)" "unprognostic (3.22e-2)" "unprognostic (2.44e-1)" "unprognostic (1.79e-1)" "unprognostic (2.49e-1)" "unprognostic (6.56e-2)" "unprognostic (4.63e-2)" "unprognostic (4.09e-2)" "unprognostic (7.58e-3)" "unprognostic (1.19e-2)" "unprognostic (3.20e-3)" "unprognostic (1.47e-3)" "unprognostic (3.39e-1)" "unprognostic (6.04e-3)" "unprognostic (1.27e-1)" "unprognostic (2.33e-2)" "unprognostic (2.15e-1)" "unprognostic (4.49e-2)" "unprognostic (1.66e-1)" "unprognostic (1.09e-2)" "unprognostic (5.48e-2)" "unprognostic (2.57e-2)" "unprognostic (4.50e-2)" "unprognostic (4.59e-2)" "unprognostic (2.24e-1)" TRIT1 "FLJ20061, IPT" ENSG00000043514 "TRNA isopentenyltransferase 1" Q9H3H1 1 39838110-39883511 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "tRNA processing" Transferase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Sertoli cells: 118.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024174, HPA027330" Approved Supported Mitochondria NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 2: Non-specific - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 1 Mitochondria "HPA024174: , HPA027330: " "unprognostic (7.97e-2)" "unprognostic (1.15e-1)" "unprognostic (1.87e-1)" "unprognostic (4.50e-1)" "unprognostic (6.59e-2)" "unprognostic (4.36e-2)" "unprognostic (1.26e-1)" "unprognostic (1.27e-3)" "unprognostic (5.32e-2)" "unprognostic (1.06e-3)" "unprognostic (7.61e-3)" "unprognostic (1.08e-1)" "unprognostic (1.37e-1)" "potential prognostic unfavorable (9.48e-7)" "unprognostic (2.10e-2)" "unprognostic (1.50e-1)" "unprognostic (1.85e-2)" "unprognostic (2.39e-1)" "unprognostic (1.86e-1)" "unprognostic (3.43e-2)" "unprognostic (2.37e-1)" "unprognostic (1.02e-1)" "unprognostic (5.50e-2)" "unprognostic (4.16e-2)" "unprognostic (2.35e-1)" "unprognostic (1.33e-1)" "unprognostic (2.88e-2)" "unprognostic (8.96e-2)" "unprognostic (2.14e-1)" "unprognostic (1.25e-1)" "unprognostic (1.13e-2)" TRMO "C9orf156, HSPC219" ENSG00000136932 "TRNA methyltransferase O" Q9BU70 9 97904489-97922500 "Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Innate lymphoid cells: 96.8;Neutrophils: 152.4;T-cells: 80.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "HPA021281, HPA052197" Approved Approved Nucleoplasm NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 55: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 20: Non-specific - Transcription regulation" 6 Nucleoplasm "HPA021281: , HPA052197: " "unprognostic (4.54e-3)" "unprognostic (4.64e-2)" "unprognostic (2.64e-3)" "unprognostic (5.87e-2)" "unprognostic (2.15e-1)" "unprognostic (5.17e-1)" "unprognostic (5.88e-2)" "unprognostic (2.26e-1)" "unprognostic (2.74e-1)" "validated prognostic favorable (2.60e-11)" "validated prognostic favorable (2.75e-5)" "unprognostic (1.26e-2)" "unprognostic (1.12e-1)" "unprognostic (5.09e-2)" "unprognostic (1.52e-2)" "unprognostic (3.45e-1)" "unprognostic (4.79e-2)" "unprognostic (2.04e-1)" "unprognostic (3.35e-1)" "unprognostic (6.86e-3)" "unprognostic (2.98e-1)" "unprognostic (1.03e-1)" "unprognostic (2.44e-2)" "unprognostic (1.07e-1)" "unprognostic (3.78e-1)" "unprognostic (1.56e-1)" "unprognostic (3.62e-1)" "unprognostic (5.58e-3)" "unprognostic (1.56e-2)" TRMT1 "FLJ20244, TRM1" ENSG00000104907 "TRNA methyltransferase 1" Q9NXH9 19 13104902-13117567 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, RNA-binding, Transferase, tRNA-binding" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Megakaryocytes: 173.1;Platelets: 74.8" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 83.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041130, HPA041380" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 64: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 47: Platelets - Hemostasis" 7 "Plasma membrane, Cytosol" Nucleoplasm "HPA041130: , HPA041380: " "unprognostic (7.62e-2)" "unprognostic (1.12e-1)" "unprognostic (3.82e-2)" "unprognostic (2.06e-2)" "unprognostic (9.90e-2)" "unprognostic (5.38e-1)" "unprognostic (3.43e-2)" "potential prognostic favorable (7.78e-4)" "unprognostic (1.96e-1)" "unprognostic (5.10e-2)" "unprognostic (1.32e-1)" "unprognostic (1.34e-1)" "unprognostic (9.54e-3)" "potential prognostic unfavorable (3.86e-6)" "unprognostic (3.64e-3)" "unprognostic (3.32e-2)" "unprognostic (6.49e-3)" "unprognostic (7.52e-2)" "unprognostic (8.26e-2)" "unprognostic (8.50e-3)" "unprognostic (1.51e-2)" "unprognostic (4.33e-2)" "unprognostic (2.58e-2)" "unprognostic (3.60e-3)" "unprognostic (1.34e-2)" "unprognostic (8.45e-3)" "unprognostic (8.97e-2)" "unprognostic (2.56e-2)" "unprognostic (5.25e-1)" "unprognostic (1.39e-1)" "unprognostic (4.82e-2)" TRMT10A "MGC27034, RG9MTD2, TRM10" ENSG00000145331 "TRNA methyltransferase 10A" Q8TBZ6 4 99546709-99564039 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Methyltransferase, Transferase" "Diabetes mellitus, Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 113.8;Late primary spermatocytes: 66.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047601, HPA058241" Uncertain Supported "Nucleoplasm,Nucleoli,Actin filaments,Cytosol" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 76: Non-specific - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 3: Early primary spermatocytes - Early meiosis" 2 "Nucleoplasm, Nucleoli, Actin filaments" Cytosol "HPA047601: , HPA058241: " "unprognostic (3.08e-3)" "unprognostic (1.48e-2)" "unprognostic (5.93e-3)" "unprognostic (7.03e-2)" "unprognostic (1.31e-1)" "unprognostic (1.14e-1)" "unprognostic (7.78e-2)" "unprognostic (1.43e-1)" "unprognostic (1.29e-3)" "validated prognostic favorable (1.24e-4)" "validated prognostic favorable (4.20e-4)" "unprognostic (4.64e-2)" "unprognostic (8.90e-2)" "unprognostic (1.28e-3)" "unprognostic (8.62e-2)" "unprognostic (1.34e-1)" "unprognostic (9.82e-2)" "unprognostic (2.51e-1)" "unprognostic (1.08e-3)" "unprognostic (4.50e-2)" "unprognostic (1.32e-1)" "unprognostic (5.02e-2)" "unprognostic (1.39e-1)" "unprognostic (3.42e-1)" "unprognostic (3.16e-2)" "unprognostic (2.14e-1)" "unprognostic (4.28e-2)" "potential prognostic unfavorable (2.80e-5)" "unprognostic (1.20e-2)" TRMT10B "bA3J10.9, FLJ31455, RG9MTD3" ENSG00000165275 "TRNA methyltransferase 10B" Q6PF06 9 37753803-37778972 "Enzymes, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021800 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 32: Basophils - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Transcription" Nucleoplasm "Plasma membrane" "HPA021800: " "unprognostic (1.05e-1)" "unprognostic (5.70e-3)" "unprognostic (1.20e-1)" "unprognostic (9.56e-2)" "unprognostic (2.74e-1)" "unprognostic (1.08e-1)" "unprognostic (2.64e-2)" "unprognostic (2.66e-2)" "unprognostic (5.52e-2)" "unprognostic (9.31e-2)" "potential prognostic favorable (3.91e-4)" "unprognostic (5.68e-3)" "unprognostic (1.22e-2)" "potential prognostic favorable (9.08e-4)" "unprognostic (1.32e-1)" "unprognostic (2.01e-1)" "unprognostic (4.71e-2)" "unprognostic (3.16e-2)" "unprognostic (8.21e-2)" "potential prognostic favorable (9.57e-4)" "unprognostic (2.42e-2)" "unprognostic (8.14e-2)" "unprognostic (1.49e-2)" "unprognostic (5.98e-2)" "potential prognostic unfavorable (3.71e-4)" "unprognostic (5.07e-2)" "unprognostic (1.64e-1)" "unprognostic (6.11e-2)" "unprognostic (2.57e-1)" TRMT10C "FLJ20432, MRPP1, RG9MTD1" ENSG00000174173 "TRNA methyltransferase 10C, mitochondrial RNase P subunit" Q7L0Y3 3 101561868-101566446 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036671 Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 17: Non-specific - RNA processing" 15 Mitochondria Nucleoplasm "HPA036671: " "unprognostic (5.32e-2)" "unprognostic (2.41e-2)" "unprognostic (1.41e-2)" "unprognostic (7.10e-2)" "unprognostic (1.49e-2)" "unprognostic (1.53e-2)" "unprognostic (1.83e-1)" "unprognostic (4.21e-2)" "unprognostic (8.52e-2)" "potential prognostic favorable (5.14e-5)" "unprognostic (1.45e-1)" "unprognostic (6.39e-2)" "potential prognostic unfavorable (6.00e-6)" "unprognostic (4.90e-3)" "potential prognostic unfavorable (9.96e-4)" "unprognostic (1.22e-1)" "unprognostic (4.82e-2)" "unprognostic (3.81e-1)" "unprognostic (9.47e-2)" "unprognostic (2.82e-2)" "unprognostic (5.67e-2)" "unprognostic (1.98e-3)" "potential prognostic favorable (2.93e-4)" "unprognostic (1.95e-1)" "unprognostic (1.14e-1)" "unprognostic (6.41e-2)" "unprognostic (2.70e-1)" "unprognostic (2.78e-2)" "unprognostic (4.23e-1)" TRMT11 "C6orf75, dJ187J11.2, MDS024, TRM11, TRMT11-1" ENSG00000066651 "TRNA methyltransferase 11 homolog" Q7Z4G4 6 125986479-126203817 "Metabolic proteins, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, RNA-binding, Transferase, tRNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 353.7;Myonuclei: 356.9;Thyrotrophs: 340.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030473 Approved "Nuclear bodies" Yes No "Cluster 43: Non-specific - Transcription & Translation" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 2: Neurons - Nucleosome" "Cluster 28: Non-specific - Nuclear processes" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 4 "Nuclear bodies" "HPA030473: " "unprognostic (2.02e-1)" "unprognostic (3.09e-2)" "unprognostic (3.39e-1)" "unprognostic (2.14e-2)" "unprognostic (6.35e-3)" "unprognostic (3.51e-1)" "unprognostic (1.29e-1)" "unprognostic (1.14e-3)" "unprognostic (4.25e-1)" "unprognostic (9.68e-2)" "unprognostic (1.23e-1)" "unprognostic (3.45e-2)" "unprognostic (5.25e-2)" "unprognostic (1.18e-1)" "unprognostic (4.42e-1)" "unprognostic (3.57e-3)" "unprognostic (2.79e-3)" "unprognostic (1.49e-1)" "unprognostic (6.35e-2)" "unprognostic (1.81e-1)" "unprognostic (9.16e-2)" "unprognostic (3.09e-2)" "unprognostic (2.14e-2)" "unprognostic (1.26e-1)" "unprognostic (8.86e-2)" "unprognostic (9.22e-3)" "unprognostic (2.22e-2)" "unprognostic (2.02e-1)" "unprognostic (1.31e-1)" "unprognostic (2.28e-1)" "unprognostic (1.96e-1)" TRMT112 "HSPC152, HSPC170, hTrm112, TRM112, TRMT11-2" ENSG00000173113 "TRNA methyltransferase activator subunit 11-2" Q9UI30 11 64316460-64317559 "Essential proteins, Predicted intracellular proteins" "rRNA processing" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 583.6;Differentiating spermatogonia: 622.9;Esophageal basal cells: 609.4;Migrating cytotrophoblasts: 648.8;Oocytes: 1151.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039901, HPA040006" Uncertain Approved Nucleoplasm,Microtubules NA NA 17000 "Cluster 46: Basophils - Proteolysis" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 36: Choroid plexus - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 13 Microtubules Nucleoplasm "HPA039901: , HPA040006: " "potential prognostic unfavorable (3.02e-4)" "unprognostic (4.48e-3)" "unprognostic (2.05e-1)" "unprognostic (5.85e-2)" "unprognostic (2.60e-2)" "unprognostic (2.60e-1)" "unprognostic (1.77e-2)" "unprognostic (1.81e-1)" "potential prognostic unfavorable (9.52e-6)" "unprognostic (9.80e-2)" "unprognostic (2.18e-1)" "unprognostic (7.73e-2)" "unprognostic (1.31e-2)" "unprognostic (2.01e-3)" "unprognostic (8.91e-3)" "unprognostic (3.66e-2)" "potential prognostic unfavorable (7.18e-4)" "unprognostic (2.77e-1)" "unprognostic (1.68e-1)" "unprognostic (2.53e-3)" "unprognostic (1.68e-2)" "unprognostic (1.03e-3)" "unprognostic (7.65e-2)" "unprognostic (6.22e-2)" "unprognostic (1.77e-1)" "unprognostic (1.44e-1)" "unprognostic (2.95e-3)" "unprognostic (4.66e-2)" "unprognostic (1.79e-1)" "unprognostic (4.00e-2)" "unprognostic (1.73e-2)" TRMT12 "FLJ20772, Trm12, TYW2" ENSG00000183665 "TRNA methyltransferase 12 homolog" Q53H54 8 124450820-124462150 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "tRNA processing" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 36.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" HPA023939 Approved Approved Nucleoplasm,Mitochondria No No "Cluster 33: Non-specific - ATP binding" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 29: Forebrain - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 20: Non-specific - Transcription regulation" 2 Nucleoplasm Mitochondria "HPA023939: " "unprognostic (6.04e-2)" "unprognostic (9.15e-3)" "unprognostic (4.54e-2)" "unprognostic (1.46e-1)" "unprognostic (4.96e-2)" "unprognostic (2.85e-3)" "unprognostic (7.12e-2)" "unprognostic (1.04e-3)" "potential prognostic unfavorable (2.54e-5)" "unprognostic (8.56e-2)" "potential prognostic favorable (8.65e-6)" "unprognostic (2.50e-3)" "unprognostic (1.07e-1)" "potential prognostic unfavorable (5.30e-4)" "unprognostic (1.34e-2)" "unprognostic (2.12e-2)" "unprognostic (9.20e-3)" "unprognostic (2.70e-1)" "unprognostic (2.18e-2)" "unprognostic (3.24e-2)" "unprognostic (2.12e-1)" "unprognostic (1.27e-1)" "unprognostic (8.11e-2)" "unprognostic (9.43e-2)" "unprognostic (1.45e-2)" "unprognostic (1.65e-1)" "unprognostic (1.76e-1)" "unprognostic (2.18e-1)" "unprognostic (1.79e-1)" "unprognostic (1.99e-2)" "unprognostic (1.05e-1)" TRMT13 "CCDC76, FLJ10287, FLJ11219" ENSG00000122435 "TRNA methyltransferase 13 homolog" Q9NUP7 1 100133150-100150496 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 133.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 92.7" "Testis - Peritubular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA028494 Approved Approved "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" "Nucleoplasm, Plasma membrane" "Nuclear bodies, Cytosol" "HPA028494: " "unprognostic (8.72e-2)" "unprognostic (2.19e-1)" "unprognostic (1.01e-1)" "unprognostic (2.45e-1)" "unprognostic (1.15e-1)" "unprognostic (2.40e-2)" "unprognostic (1.35e-1)" "unprognostic (1.45e-1)" "unprognostic (5.35e-2)" "unprognostic (2.74e-1)" "unprognostic (5.19e-3)" "unprognostic (8.07e-2)" "potential prognostic unfavorable (1.10e-4)" "unprognostic (3.29e-1)" "unprognostic (2.43e-1)" "unprognostic (1.83e-3)" "unprognostic (5.86e-3)" "unprognostic (2.34e-1)" "unprognostic (9.12e-2)" "unprognostic (3.96e-1)" "unprognostic (3.45e-3)" "unprognostic (2.56e-2)" "potential prognostic favorable (9.17e-5)" "unprognostic (3.16e-1)" "unprognostic (4.67e-2)" "unprognostic (5.29e-2)" "unprognostic (8.21e-2)" "unprognostic (3.19e-2)" "unprognostic (4.61e-2)" TRMT1L C1orf25 ENSG00000121486 "TRNA methyltransferase 1 like" Q7Z2T5 1 185118101-185157072 "Predicted intracellular proteins" "tRNA processing" "Methyltransferase, RNA-binding, Transferase, tRNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 166.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026728, HPA054464" Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 39: Testis - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" 46 Nucleoplasm Nucleoli "HPA026728: , HPA054464: " "unprognostic (3.72e-1)" "unprognostic (1.05e-2)" "unprognostic (2.18e-1)" "unprognostic (8.62e-2)" "unprognostic (2.55e-1)" "unprognostic (2.06e-1)" "unprognostic (1.50e-2)" "unprognostic (1.25e-1)" "potential prognostic unfavorable (8.97e-4)" "potential prognostic favorable (3.84e-8)" "unprognostic (5.12e-3)" "unprognostic (9.75e-2)" "unprognostic (7.22e-2)" "unprognostic (4.49e-2)" "unprognostic (1.71e-1)" "unprognostic (1.10e-1)" "unprognostic (1.98e-1)" "unprognostic (1.85e-1)" "unprognostic (1.16e-1)" "unprognostic (2.71e-3)" "unprognostic (2.13e-1)" "unprognostic (1.05e-1)" "unprognostic (4.24e-2)" "unprognostic (2.35e-2)" "unprognostic (1.90e-1)" "unprognostic (6.92e-2)" "unprognostic (9.37e-2)" "unprognostic (1.62e-1)" "unprognostic (1.77e-2)" "unprognostic (1.92e-1)" TRMT2A HTF9C ENSG00000099899 "TRNA methyltransferase 2 homolog A" Q8IZ69 22 20111875-20117392 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, tRNA processing" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Early spermatids: 166.0;Late spermatids: 351.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001077 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 70: Non-specific - Protein processing" "Cluster 27: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 12 "Nucleoplasm, Cytosol" "HPA001077: " "unprognostic (2.90e-1)" "unprognostic (2.89e-2)" "unprognostic (2.12e-2)" "unprognostic (1.72e-1)" "unprognostic (8.56e-2)" "unprognostic (1.25e-2)" "unprognostic (2.70e-1)" "unprognostic (1.62e-2)" "unprognostic (1.60e-2)" "unprognostic (2.32e-1)" "unprognostic (1.58e-3)" "unprognostic (4.10e-2)" "unprognostic (7.70e-2)" "unprognostic (3.28e-3)" "unprognostic (3.90e-2)" "unprognostic (1.61e-1)" "unprognostic (3.49e-2)" "unprognostic (1.52e-2)" "unprognostic (1.06e-1)" "unprognostic (4.63e-1)" "unprognostic (4.08e-2)" "unprognostic (1.89e-2)" "unprognostic (1.88e-3)" "unprognostic (5.32e-3)" "unprognostic (3.54e-2)" "unprognostic (4.45e-3)" "unprognostic (1.08e-1)" "unprognostic (1.22e-1)" "unprognostic (3.78e-1)" "unprognostic (2.08e-1)" "unprognostic (1.19e-1)" TRMT2B "CXorf34, FLJ12687" ENSG00000188917 "TRNA methyltransferase 2 homolog B" Q96GJ1 X 101009346-101052116 "Enzymes, Predicted intracellular proteins" "rRNA processing, tRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003745, HPA035120, HPA040814" Uncertain Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 52: Non-specific - Cellular respiration" "Cluster 49: Hindbrain - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 2 Nucleoplasm "Nuclear bodies" "HPA003745: , HPA035120: , HPA040814: " "unprognostic (9.26e-2)" "potential prognostic unfavorable (2.78e-5)" "unprognostic (9.55e-3)" "unprognostic (1.59e-1)" "unprognostic (1.79e-1)" "unprognostic (1.73e-1)" "unprognostic (1.32e-1)" "unprognostic (5.84e-2)" "unprognostic (3.54e-1)" "unprognostic (2.90e-3)" "potential prognostic favorable (3.97e-5)" "unprognostic (7.13e-2)" "potential prognostic favorable (3.67e-4)" "unprognostic (3.83e-2)" "unprognostic (2.49e-1)" "unprognostic (2.06e-1)" "unprognostic (3.33e-2)" "unprognostic (5.93e-2)" "unprognostic (1.18e-1)" "unprognostic (3.32e-1)" "unprognostic (2.32e-1)" "unprognostic (1.02e-1)" "unprognostic (7.52e-2)" "unprognostic (6.49e-2)" "unprognostic (1.82e-2)" "unprognostic (9.94e-2)" "unprognostic (1.29e-2)" "unprognostic (2.97e-2)" "unprognostic (2.08e-1)" "unprognostic (2.35e-2)" "unprognostic (2.23e-1)" TRMT44 "C4orf23, FLJ35725, METTL19, TRM44" ENSG00000155275 "TRNA methyltransferase 44 homolog" Q8IYL2 4 8436140-8493531 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 160.7;Oocytes: 193.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038532, HPA045461" Uncertain Approved "Nuclear bodies,Cytosol" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 49: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 5 Cytosol "Nuclear bodies" "HPA038532: , HPA045461: " "unprognostic (2.67e-3)" "unprognostic (3.11e-1)" "unprognostic (6.97e-2)" "unprognostic (7.12e-3)" "unprognostic (1.01e-1)" "unprognostic (1.29e-1)" "potential prognostic favorable (7.76e-5)" "unprognostic (3.63e-2)" "unprognostic (3.02e-2)" "validated prognostic favorable (7.29e-5)" "validated prognostic favorable (8.14e-5)" "unprognostic (1.21e-1)" "unprognostic (1.29e-1)" "unprognostic (2.83e-1)" "unprognostic (1.05e-2)" "unprognostic (5.54e-2)" "unprognostic (2.92e-1)" "unprognostic (1.27e-1)" "unprognostic (3.76e-2)" "unprognostic (1.76e-2)" "unprognostic (3.68e-1)" "unprognostic (6.31e-2)" "unprognostic (1.54e-2)" "potential prognostic favorable (3.62e-4)" "unprognostic (2.26e-1)" "unprognostic (1.02e-1)" "unprognostic (2.20e-1)" "unprognostic (1.59e-1)" "unprognostic (2.61e-1)" TRMT5 "KIAA1393, TRM5" ENSG00000126814 "TRNA methyltransferase 5" Q32P41 14 60971441-60981170 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 251.7;Late primary spermatocytes: 140.4;Late spermatids: 57.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000943 Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 2 "Nucleoplasm, Nucleoli" "HPA000943: " "unprognostic (2.15e-1)" "unprognostic (2.72e-1)" "unprognostic (3.84e-1)" "unprognostic (1.45e-2)" "unprognostic (1.45e-1)" "unprognostic (1.61e-1)" "unprognostic (8.57e-3)" "unprognostic (6.99e-2)" "unprognostic (2.61e-2)" "unprognostic (3.00e-3)" "potential prognostic favorable (1.27e-5)" "unprognostic (7.86e-3)" "unprognostic (3.42e-2)" "potential prognostic unfavorable (1.78e-4)" "unprognostic (3.02e-1)" "unprognostic (1.30e-2)" "unprognostic (1.14e-2)" "unprognostic (1.80e-3)" "unprognostic (3.17e-2)" "unprognostic (2.97e-1)" "potential prognostic unfavorable (7.06e-4)" "unprognostic (1.04e-3)" "unprognostic (2.00e-2)" "unprognostic (3.39e-2)" "unprognostic (1.39e-3)" "unprognostic (2.22e-1)" "unprognostic (1.41e-1)" "unprognostic (2.88e-1)" "unprognostic (1.16e-1)" "unprognostic (2.04e-3)" "unprognostic (1.67e-1)" TRMT6 "CGI-09, GCD10, Gcd10p, MGC5029" ENSG00000089195 "TRNA methyltransferase 6 non-catalytic subunit" Q9UJA5 20 5937228-5950558 "Predicted intracellular proteins" "tRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 114.8;Early primary spermatocytes: 102.8;Oocytes: 147.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047032, HPA050408" Approved Enhanced "Nucleoplasm,Cell Junctions" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 37: Neurons - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 19 Nucleoplasm "Cell Junctions" "HPA047032: , HPA050408: " "unprognostic (1.33e-1)" "unprognostic (2.88e-2)" "unprognostic (1.45e-1)" "unprognostic (2.85e-2)" "unprognostic (6.36e-2)" "unprognostic (9.46e-2)" "unprognostic (1.54e-1)" "unprognostic (1.23e-2)" "unprognostic (3.62e-2)" "unprognostic (1.30e-2)" "unprognostic (1.80e-2)" "unprognostic (2.05e-1)" "unprognostic (2.96e-3)" "validated prognostic unfavorable (7.21e-8)" "validated prognostic unfavorable (9.04e-6)" "unprognostic (3.76e-3)" "unprognostic (1.04e-1)" "unprognostic (9.65e-2)" "unprognostic (3.07e-1)" "unprognostic (1.93e-1)" "unprognostic (3.03e-1)" "unprognostic (1.87e-1)" "unprognostic (2.53e-1)" "unprognostic (1.12e-1)" "unprognostic (2.63e-2)" "unprognostic (1.35e-2)" "unprognostic (1.29e-1)" "unprognostic (1.55e-1)" "unprognostic (4.22e-1)" "unprognostic (4.59e-3)" "unprognostic (1.90e-1)" TRMT61A "C14orf172, FLJ40452, GCD14, Gcd14p, hTRM61" ENSG00000166166 "TRNA methyltransferase 61A" Q96FX7 14 103529196-103537073 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 35.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 10.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024269 Approved Mitochondria NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 74: Non-specific - Signal transduction" "Cluster 6: Non-specific - Immune response" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 17: Non-specific - RNA processing" 21 Mitochondria "HPA024269: " "unprognostic (3.05e-1)" "unprognostic (1.34e-1)" "unprognostic (1.94e-1)" "unprognostic (1.15e-1)" "unprognostic (3.39e-2)" "unprognostic (5.77e-2)" "unprognostic (1.55e-1)" "unprognostic (2.93e-2)" "unprognostic (2.56e-2)" "unprognostic (3.89e-1)" "unprognostic (2.62e-1)" "unprognostic (2.87e-1)" "unprognostic (3.87e-2)" "potential prognostic unfavorable (1.53e-5)" "unprognostic (5.97e-3)" "unprognostic (2.90e-1)" "unprognostic (2.34e-1)" "unprognostic (2.49e-1)" "unprognostic (1.03e-1)" "unprognostic (2.12e-1)" "unprognostic (8.38e-2)" "unprognostic (6.86e-2)" "unprognostic (2.47e-1)" "potential prognostic unfavorable (1.42e-4)" "unprognostic (2.19e-2)" "unprognostic (1.80e-1)" "unprognostic (1.01e-1)" "unprognostic (1.20e-1)" "unprognostic (1.09e-1)" "unprognostic (8.30e-2)" "unprognostic (2.96e-1)" TRMT61B FLJ20628 ENSG00000171103 "TRNA methyltransferase 61B" Q9BVS5 2 28849821-28870309 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "HPA026747, HPA026751" Enhanced Uncertain Cytosol NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 31: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 35: Neurons - Synaptic function & neurogenesis" 41 Cytosol "HPA026747: , HPA026751: " "unprognostic (2.76e-2)" "unprognostic (1.38e-2)" "unprognostic (7.36e-2)" "unprognostic (1.18e-2)" "unprognostic (2.82e-3)" "unprognostic (4.28e-2)" "unprognostic (3.24e-1)" "unprognostic (1.05e-2)" "unprognostic (6.33e-2)" "unprognostic (4.59e-2)" "unprognostic (1.25e-3)" "unprognostic (1.35e-1)" "unprognostic (2.03e-1)" "validated prognostic unfavorable (2.49e-6)" "validated prognostic unfavorable (2.43e-4)" "unprognostic (3.88e-1)" "unprognostic (8.64e-2)" "potential prognostic favorable (7.92e-4)" "unprognostic (1.20e-1)" "unprognostic (3.93e-2)" "unprognostic (1.03e-2)" "unprognostic (1.24e-1)" "unprognostic (3.98e-2)" "unprognostic (4.81e-2)" "unprognostic (6.90e-3)" "unprognostic (3.02e-2)" "unprognostic (2.25e-2)" "unprognostic (6.97e-2)" "unprognostic (1.49e-1)" "unprognostic (2.73e-2)" "unprognostic (1.84e-1)" TRMT9B "C8orf79, FLJ36980, hTRM9L, KIAA1456, TRM9L" ENSG00000250305 "TRNA methyltransferase 9B (putative)" Q9P272 8 12945642-13031503 "Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "brain: 64.0;choroid plexus: 82.2;retina: 22.7;thyroid gland: 31.5" "Cell type enriched" "Detected in many" 10 "Choroid plexus epithelial cells: 3989.2" "Cell type enriched" "Detected in all" 5 "choroid plexus epithelial cell: 4192.3" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 7.9;Thyroid Carcinoma (TCGA): 7.0" "Group enriched" "Detected in all" 8 "cerebellum: 261.6;choroid plexus: 811.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 16 "Bone cancer: 47.9" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 41.6" HPA024673 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 5: Non-specific - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 101: Choroid plexus epithelial cells - Ion transport" Nucleoplasm Cytosol "HPA024673: " "unprognostic (7.01e-2)" "unprognostic (1.11e-2)" "unprognostic (1.05e-1)" "unprognostic (1.11e-3)" "unprognostic (4.63e-2)" "validated prognostic favorable (4.76e-4)" "validated prognostic favorable (1.80e-4)" "potential prognostic favorable (5.68e-4)" "unprognostic (2.95e-2)" "unprognostic (6.87e-2)" "unprognostic (1.25e-1)" "unprognostic (2.20e-1)" "unprognostic (1.44e-1)" "unprognostic (6.37e-2)" "potential prognostic unfavorable (5.45e-4)" "unprognostic (3.06e-3)" TRMU "FLJ10140, MTO2, MTU1, TRMT" ENSG00000100416 "TRNA mitochondrial 2-thiouridylase" O75648 22 46330875-46357340 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "RNA-binding, Transferase, tRNA-binding" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000824, HPA035273, HPA043300" Uncertain Supported Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 70: Non-specific - Protein processing" "Cluster 45: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 2 Mitochondria "HPA000824: , HPA035273: , HPA043300: " "unprognostic (1.28e-1)" "unprognostic (3.50e-3)" "unprognostic (2.39e-1)" "unprognostic (8.89e-2)" "unprognostic (4.44e-3)" "unprognostic (3.84e-2)" "unprognostic (2.52e-1)" "unprognostic (2.92e-2)" "unprognostic (2.40e-1)" "unprognostic (2.82e-2)" "potential prognostic favorable (6.22e-4)" "unprognostic (4.69e-2)" "unprognostic (3.97e-2)" "potential prognostic unfavorable (8.50e-7)" "unprognostic (2.31e-2)" "unprognostic (9.27e-3)" "unprognostic (5.09e-2)" "unprognostic (1.91e-3)" "unprognostic (1.01e-1)" "unprognostic (1.40e-1)" "unprognostic (2.80e-3)" "unprognostic (1.18e-3)" "unprognostic (1.30e-3)" "unprognostic (1.62e-1)" "unprognostic (2.60e-2)" "unprognostic (1.38e-3)" "unprognostic (3.07e-2)" "unprognostic (8.31e-3)" "unprognostic (9.20e-2)" "unprognostic (4.08e-1)" "unprognostic (1.26e-2)" TRNAU1AP "FLJ20503, SECP43, TRSPAP1" ENSG00000180098 "TRNA selenocysteine 1 associated protein 1" Q9NX07 1 28553085-28578545 "Predicted intracellular proteins" "Protein biosynthesis" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032068, HPA032069" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 41: Basophils - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 5 Nucleoplasm Cytosol "HPA032068: , HPA032069: " "unprognostic (1.63e-1)" "unprognostic (1.88e-1)" "unprognostic (1.22e-2)" "unprognostic (6.67e-2)" "unprognostic (4.71e-1)" "unprognostic (1.51e-1)" "unprognostic (3.33e-3)" "unprognostic (3.91e-2)" "unprognostic (2.54e-2)" "unprognostic (2.60e-1)" "potential prognostic favorable (6.41e-5)" "unprognostic (4.71e-3)" "unprognostic (1.29e-2)" "validated prognostic unfavorable (4.72e-6)" "validated prognostic unfavorable (4.46e-4)" "unprognostic (1.33e-1)" "unprognostic (2.20e-1)" "unprognostic (1.02e-1)" "unprognostic (2.75e-1)" "unprognostic (4.51e-2)" "unprognostic (1.78e-1)" "unprognostic (8.73e-2)" "unprognostic (1.83e-2)" "unprognostic (2.31e-1)" "unprognostic (1.88e-1)" "unprognostic (9.18e-2)" "unprognostic (6.26e-2)" "unprognostic (3.48e-1)" "unprognostic (3.32e-2)" "unprognostic (9.74e-3)" "unprognostic (1.47e-1)" TRNP1 "C1orf225, TRNP" ENSG00000253368 "TMF1 regulated nuclear protein 1" Q6NT89 1 26993692-27000886 "Predicted intracellular proteins" "Cell cycle, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 81.2;retina: 78.2;stomach 1: 117.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 78.7;Breast myoepithelial cells: 78.4;Esophageal apical cells: 293.2;Foveolar cells: 112.0;Pancreatic duct cells: 98.1;Retinal bipolar cells: 373.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Pituitary gland - Thyrotropes, Prostate - Smooth muscle cells, Spleen - Fibroblasts_1, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 1 "unprognostic (1.39e-1)" "unprognostic (2.94e-2)" "unprognostic (1.02e-1)" "unprognostic (2.73e-2)" "unprognostic (1.30e-1)" "potential prognostic unfavorable (2.18e-4)" "unprognostic (7.80e-3)" "unprognostic (4.60e-3)" "unprognostic (1.70e-2)" "unprognostic (1.10e-1)" "potential prognostic unfavorable (1.10e-5)" "unprognostic (3.15e-3)" "potential prognostic unfavorable (4.14e-4)" "validated prognostic unfavorable (1.90e-5)" "validated prognostic unfavorable (7.72e-4)" "unprognostic (1.73e-1)" "unprognostic (3.08e-1)" "unprognostic (8.31e-2)" "unprognostic (1.00e-2)" "unprognostic (1.89e-1)" "unprognostic (2.38e-2)" "unprognostic (2.70e-1)" "unprognostic (1.80e-2)" "unprognostic (9.30e-3)" "unprognostic (1.43e-1)" "unprognostic (2.82e-1)" "unprognostic (2.44e-1)" "unprognostic (1.58e-1)" "unprognostic (1.50e-1)" "unprognostic (1.29e-1)" "unprognostic (4.94e-2)" TRNT1 "CCA1, CGI-47, MtCCA" ENSG00000072756 "TRNA nucleotidyl transferase 1" Q96Q11 3 3126933-3153435 "Disease related genes, Enzymes, Essential proteins, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "Nucleotidyltransferase, RNA-binding, Transferase" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036938 Uncertain Supported Mitochondria Yes No "Cluster 41: Basophils - Unknown function" "Cluster 40: Non-specific - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" Mitochondria "HPA036938: " "unprognostic (1.15e-1)" "unprognostic (1.10e-2)" "unprognostic (1.01e-1)" "unprognostic (1.37e-2)" "unprognostic (1.07e-2)" "unprognostic (1.30e-2)" "unprognostic (1.78e-1)" "unprognostic (3.72e-2)" "unprognostic (1.09e-1)" "unprognostic (2.09e-2)" "potential prognostic favorable (1.08e-5)" "unprognostic (2.09e-1)" "unprognostic (9.88e-2)" "unprognostic (3.36e-3)" "unprognostic (4.54e-2)" "unprognostic (2.95e-2)" "unprognostic (1.42e-1)" "unprognostic (2.78e-1)" "unprognostic (1.97e-1)" "unprognostic (3.00e-2)" "unprognostic (3.86e-2)" "potential prognostic unfavorable (5.73e-4)" "unprognostic (6.42e-3)" "unprognostic (8.87e-2)" "unprognostic (1.67e-1)" "potential prognostic favorable (1.31e-5)" "unprognostic (5.78e-2)" "unprognostic (1.43e-1)" "unprognostic (2.42e-1)" "unprognostic (3.97e-1)" "unprognostic (1.73e-1)" TRO "KIAA1114, MAGE-D3, MAGED3" ENSG00000067445 Trophinin Q12816 X 54920462-54931431 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 29.1" "Cell type enhanced" "Detected in many" "Astrocytes: 13.3;Brain excitatory neurons: 17.4;Brain inhibitory neurons: 21.5;Lactotrophs: 21.3;Oligodendrocyte progenitor cells: 28.7;Oligodendrocytes: 17.7;Other brain neurons: 33.2;Pituitary stem cells: 13.0;Somatotrophs: 15.6" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 25.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 2.1" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Neuroblastoma: 29.3;testis cancer: 68.3" "Colon - Enteric glia cells, Liver - Hepatocytes, Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000537 Approved "Cell Junctions,Cytosol" NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 3 "Cell Junctions" Cytosol "HPA000537: " "unprognostic (7.05e-2)" "unprognostic (1.29e-1)" "unprognostic (2.29e-2)" "unprognostic (2.86e-2)" "unprognostic (3.57e-2)" "unprognostic (8.23e-2)" "potential prognostic favorable (9.03e-7)" "unprognostic (9.24e-2)" "unprognostic (3.25e-1)" "unprognostic (2.66e-2)" "unprognostic (1.41e-1)" "unprognostic (6.81e-3)" "unprognostic (4.95e-2)" "potential prognostic favorable (2.22e-4)" "unprognostic (9.31e-2)" "unprognostic (4.60e-2)" "unprognostic (3.05e-1)" "unprognostic (3.07e-1)" "unprognostic (1.38e-1)" "unprognostic (1.68e-1)" "unprognostic (1.01e-1)" "unprognostic (3.43e-2)" "unprognostic (1.76e-1)" "unprognostic (1.21e-2)" "unprognostic (1.68e-3)" "unprognostic (1.58e-1)" "unprognostic (2.02e-3)" "unprognostic (1.54e-2)" TROAP TASTIN ENSG00000135451 "Trophinin associated protein" Q12815 12 49323236-49331731 "Essential proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 48.3;lymphoid tissue: 34.3;testis: 27.2" "Cell type enhanced" "Detected in many" "Early spermatids: 68.0;Enteric transient amplifying cells: 34.9;Erythrocyte progenitors: 33.1;Esophageal basal cells: 49.6;Extravillous trophoblasts: 27.3;Gastric progenitor cells: 75.6;Hofbauer cells: 27.7;Late primary spermatocytes: 85.0;Late spermatids: 103.5;Megakaryocyte progenitors: 24.4;Migrating cytotrophoblasts: 24.6;Monocyte progenitors: 44.7;Oocytes: 27.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "T-reg: 8.7" "Lineage enriched" "Detected in many" 4 "T-cells: 8.7" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Mitotic cells (Thyroid)" "Not detected" "Not detected" "Not detected" "Not detected" HPA044102 Uncertain NA Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 38: Non-specific - Transcription" "Cluster 27: Non-specific - Cell proliferation" 33 "HPA044102: " "unprognostic (2.25e-2)" "unprognostic (3.42e-2)" "unprognostic (2.17e-1)" "unprognostic (1.48e-1)" "unprognostic (1.59e-1)" "unprognostic (2.42e-1)" "unprognostic (6.64e-2)" "unprognostic (3.49e-2)" "unprognostic (2.93e-2)" "potential prognostic unfavorable (1.36e-7)" "validated prognostic unfavorable (2.02e-13)" "validated prognostic unfavorable (1.28e-5)" "potential prognostic unfavorable (1.65e-14)" "validated prognostic unfavorable (6.22e-6)" "validated prognostic unfavorable (4.42e-8)" "potential prognostic unfavorable (2.80e-4)" "unprognostic (7.29e-3)" "unprognostic (1.34e-2)" "unprognostic (3.67e-3)" "unprognostic (4.42e-2)" "unprognostic (4.81e-2)" "validated prognostic unfavorable (1.43e-4)" "validated prognostic unfavorable (4.13e-4)" "unprognostic (2.03e-1)" "unprognostic (3.34e-1)" "unprognostic (8.99e-2)" "unprognostic (3.14e-2)" "unprognostic (1.99e-1)" "unprognostic (2.47e-1)" "unprognostic (1.95e-2)" "unprognostic (1.39e-3)" TRPA1 ANKTM1 ENSG00000104321 "Transient receptor potential cation channel subfamily A member 1" O75762 8 72019917-72075584 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Sensory transduction, Transport" "Calcium channel, Ion channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 8.6;stomach 1: 9.7;urinary bladder: 25.9" "Cell type enhanced" "Detected in some" "Adipocytes: 49.1;Fibro-adipogenic progenitors: 40.1;Fibroblasts: 59.2;Goblet cells: 74.3;Late primary spermatocytes: 12.8;Myosatellite cells: 53.6;Pericytes: 23.7;Vascular smooth muscle cells: 22.7" "Cell type enhanced" "Detected in many" "hippocampal dentate gyrus: 14.5;pericyte: 10.3" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 7.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 7.2" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA "Cluster 17: Intestine - Digestion" "Cluster 51: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "unprognostic (8.87e-3)" "unprognostic (2.34e-1)" "unprognostic (3.65e-1)" "unprognostic (7.23e-3)" "unprognostic (1.02e-1)" "potential prognostic favorable (2.64e-5)" "unprognostic (6.68e-2)" "unprognostic (2.66e-2)" "unprognostic (1.74e-2)" "unprognostic (3.60e-2)" "unprognostic (6.90e-2)" "unprognostic (1.92e-1)" "unprognostic (3.17e-2)" "unprognostic (4.17e-2)" "unprognostic (4.47e-2)" "unprognostic (3.27e-1)" TRPC1 HTRP-1 ENSG00000144935 "Transient receptor potential cation channel subfamily C member 1" P48995 3 142724034-142807888 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibro-adipogenic progenitors: 243.1;Other brain neurons: 225.2;Pituicytes/FSCs: 252.9;Thyrotrophs: 248.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009387, HPA021130" Supported Approved Vesicles NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 37: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 14 Vesicles "CAB009387: , HPA021130: " "unprognostic (4.45e-2)" "unprognostic (7.92e-2)" "unprognostic (2.58e-1)" "unprognostic (1.53e-2)" "unprognostic (1.16e-1)" "unprognostic (2.30e-1)" "unprognostic (3.75e-2)" "unprognostic (2.96e-1)" "unprognostic (1.86e-1)" "unprognostic (6.85e-2)" "unprognostic (3.58e-2)" "potential prognostic unfavorable (6.02e-4)" "unprognostic (3.54e-2)" "unprognostic (1.50e-1)" "unprognostic (1.48e-1)" "unprognostic (1.37e-1)" "unprognostic (5.72e-2)" "unprognostic (7.35e-2)" "unprognostic (9.18e-3)" "unprognostic (3.19e-2)" "unprognostic (1.21e-1)" "potential prognostic favorable (5.96e-4)" "unprognostic (6.20e-2)" "unprognostic (6.16e-3)" "unprognostic (3.20e-1)" "unprognostic (7.39e-2)" "potential prognostic unfavorable (9.75e-5)" TRPC3 ENSG00000138741 "Transient receptor potential cation channel subfamily C member 3" Q13507 4 121874481-121952060 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.7;pituitary gland: 7.0;retina: 3.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 43.5;Gonadotrophs: 33.1;Lactotrophs: 197.4;Oligodendrocyte progenitor cells: 53.0;Other brain neurons: 224.0;Pericytes: 62.7;Pituicytes/FSCs: 60.9;Retinal ganglion cells: 96.6;Rod photoreceptor cells: 83.4;Somatotrophs: 41.1;Thyrotrophs: 109.4" "Cell type enriched" "Detected in many" 6 "pericyte: 950.2" "Cancer enhanced" "Detected in single" "Kidney Chromophobe (TCGA): 2.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Breast - Endothelial cells, Testis - Spermatogonia" "Region enhanced" "Detected in all" "cerebellum: 57.8" "Low region specificity" "Detected in all" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" 7 "unprognostic (6.57e-2)" "potential prognostic favorable (2.30e-4)" "unprognostic (3.67e-2)" TRPC4 "HTRP4, TRP4" ENSG00000133107 "Transient receptor potential cation channel subfamily C member 4" Q9UBN4 13 37632063-37869802 "Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 11.2;smooth muscle: 11.8" "Cell type enhanced" "Detected in many" "Bergmann glia: 78.8;Brain excitatory neurons: 80.8;Brain inhibitory neurons: 117.4;Decidual stromal cells: 134.1;Endometrial stromal cells: 74.0;Fibroblasts: 34.6;Hepatic stellate cells: 38.7;Other brain neurons: 104.5;Pancreatic islet cells: 56.3;Pericytes: 127.7;Vascular smooth muscle cells: 44.1" "Cell type enhanced" "Detected in many" "hippocampal CA1-3: 411.7;pericyte: 396.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "thyroid cancer: 9.8" "Adipose subcutaneous - Smooth muscle cells, Prostate - Fibroblasts, Skeletal muscle - Endothelial cells, Spleen - Smooth muscle cells" "Region enhanced" "Detected in many" "basal ganglia: 43.1" "Low region specificity" "Detected in all" NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 14: Neurons - Synaptic function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 35: Neurons - Synaptic function & neurogenesis" 6 "unprognostic (2.92e-1)" "unprognostic (9.31e-3)" "unprognostic (1.24e-1)" "unprognostic (2.76e-1)" "unprognostic (1.86e-3)" "potential prognostic favorable (5.69e-4)" "unprognostic (9.77e-3)" "unprognostic (1.71e-2)" "unprognostic (1.10e-1)" "unprognostic (1.25e-1)" "unprognostic (1.15e-1)" TRPC4AP "C20orf188, dJ756N5.2, DKFZp586C1223, DKFZP727M231, PPP1R158, TRRP4AP" ENSG00000100991 "Transient receptor potential cation channel subfamily C member 4 associated protein" Q8TEL6 20 35002404-35092807 "Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051197, HPA065061" Uncertain Supported Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 24: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 16 Cytosol "HPA051197: , HPA065061: " "unprognostic (7.25e-2)" "unprognostic (5.63e-2)" "unprognostic (2.67e-1)" "unprognostic (2.61e-2)" "unprognostic (1.09e-1)" "unprognostic (2.51e-1)" "unprognostic (5.24e-2)" "unprognostic (3.25e-1)" "unprognostic (2.81e-1)" "unprognostic (1.20e-2)" "unprognostic (6.95e-2)" "unprognostic (4.74e-3)" "unprognostic (2.69e-1)" "potential prognostic unfavorable (7.60e-6)" "unprognostic (9.35e-3)" "unprognostic (1.43e-1)" "unprognostic (1.00e-2)" "unprognostic (2.41e-2)" "unprognostic (3.02e-1)" "unprognostic (9.62e-2)" "unprognostic (4.96e-2)" "unprognostic (4.78e-2)" "potential prognostic unfavorable (1.90e-4)" "unprognostic (2.51e-1)" "potential prognostic favorable (6.92e-5)" "unprognostic (3.42e-2)" "unprognostic (2.88e-2)" "unprognostic (2.52e-1)" "unprognostic (1.06e-1)" "unprognostic (2.50e-1)" "unprognostic (1.83e-1)" TRPC5 PPP1R159 ENSG00000072315 "Transient receptor potential cation channel subfamily C member 5" Q9UL62 X 111768011-112082776 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.3" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 65.4;Brain inhibitory neurons: 88.1;Epicardial cells: 22.7;Gonadotrophs: 16.8;Oligodendrocytes: 22.0;Other brain neurons: 107.8" "Cell type enhanced" "Detected in all" "cerebellar inhibitory: 372.8;midbrain-derived inhibitory: 346.7" "Cancer enriched" "Detected in single" 9 "Thyroid Carcinoma (TCGA): 8.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 1: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 3 "unprognostic (8.15e-3)" "unprognostic (1.41e-2)" TRPC5OS TRPC5-AS1 ENSG00000204025 "TRPC5 opposite strand" A6NMA1 X 111876051-111903990 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 33 "testis: 20.2" "Cell type enriched" "Detected in some" 27 "Sertoli cells: 127.3" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 11.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Sertoli cells" "Not detected" "Not detected" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 1: Neurons - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" "unprognostic (1.97e-1)" TRPC6 "FSGS2, TRP6" ENSG00000137672 "Transient receptor potential cation channel subfamily C member 6" Q9Y210 11 101451564-101872562 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 12.6;placenta: 19.6" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 76.3;Choroid plexus epithelial cells: 106.8;Ependymal cells: 247.3;Fallopian tube ciliated cells: 63.2;Megakaryocyte progenitors: 129.9;Pericytes: 196.8;Podocytes: 241.3;Vascular smooth muscle cells: 93.0" "Cell type enhanced" "Detected in many" "ependymal cell: 250.7" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 7.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "eosinophil: 2.3" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.3" "Cancer enhanced" "Detected in some" "ovarian cancer: 1.4;testis cancer: 1.9" "Adipose subcutaneous - Endothelial cells, Minor Salivary Gland - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA045098 Approved NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 17: Choroid plexus - Cilium" "Cluster 15: Kidney cancer - Membrane components" "Cluster 110: Mural cells - ECM organization" 6 "HPA045098: " "unprognostic (1.06e-1)" "unprognostic (5.46e-2)" "unprognostic (2.11e-1)" "unprognostic (3.86e-1)" "unprognostic (4.95e-2)" "unprognostic (1.85e-2)" "validated prognostic favorable (1.39e-5)" "validated prognostic favorable (2.90e-5)" "unprognostic (4.59e-2)" "unprognostic (1.51e-1)" "unprognostic (2.16e-2)" "unprognostic (6.72e-2)" "unprognostic (5.69e-2)" "unprognostic (1.31e-2)" "unprognostic (1.19e-1)" "unprognostic (2.71e-3)" "unprognostic (7.63e-2)" "unprognostic (1.06e-2)" "unprognostic (4.18e-2)" TRPC7 ENSG00000069018 "Transient receptor potential cation channel subfamily C member 7" Q9HCX4 5 136212745-136365545 "Predicted membrane proteins, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Brain inhibitory neurons: 24.7;Neuroendocrine cells: 20.1;Oocytes: 27.6;Other brain neurons: 33.6;Retinal bipolar cells: 132.8;Retinal ganglion cells: 50.2;Thyrotrophs: 42.0" "Cell type enhanced" "Detected in many" "lower rhombic lip: 52.8;midbrain-derived inhibitory: 97.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adrenal gland - Adrenal medulla cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB022592, HPA031126" Uncertain NA NA "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 1 "CAB022592: , HPA031126: " TRPM1 "CSNB1C, LTRPC1, MLSN1" ENSG00000134160 "Transient receptor potential cation channel subfamily M member 1" Q7Z4N2 15 31001065-31161160 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sensory transduction, Transport, Vision" "Ion channel, Ligand-gated ion channel, Receptor" "Congenital stationary night blindness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "retina: 16.2;skin 1: 4.6" "Group enriched" "Detected in some" 5 "Melanocytes: 201.7;Retinal bipolar cells: 275.6;Retinal pigment epithelial cells: 204.6" "Cell type enriched" "Detected in some" 4 "oligodendrocyte: 62.9" "Cancer enriched" "Detected in single" 263 "Skin Cutaneous Melanoma (TCGA): 35.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 248 "skin cancer: 38.0" "Adipose visceral - Adipocytes (Visceral), Skin - Melanocytes, Testis - Early spermatids" "Not detected" "Not detected" "Region enhanced" "Detected in single" "olfactory bulb: 1.0" "HPA014779, HPA071139" Enhanced Uncertain "Golgi apparatus,Plasma membrane,Centriolar satellite" NA NA "Cluster 42: Retina - Visual perception" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "Centriolar satellite" "Golgi apparatus, Plasma membrane" "HPA014779: , HPA071139: " "unprognostic (4.56e-2)" TRPM2 "EREG1, KNP3, LTRPC2, NUDT9H, NUDT9L1, TRPC7" ENSG00000142185 "Transient receptor potential cation channel subfamily M member 2" O94759 21 44350163-44443081 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Sodium transport, Transport" "Calcium channel, Ion channel, Sodium channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.0" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 49.3;Brain inhibitory neurons: 61.6;Hofbauer cells: 103.7;Macrophages: 113.2;Microglia: 177.7;Monocyte progenitors: 44.5;Neutrophil progenitors: 136.3;Neutrophils: 163.7;pDCs: 132.6;Retinal ganglion cells: 108.2" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 249.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 10.2" "Group enriched" "Detected in many" 4 "dendritic cells: 10.2;monocytes: 5.6" "Cancer enriched" "Detected in many" 7 "Leukemia: 36.7" "Adipose visceral - Macrophages, Adrenal gland - Macrophages, Kidney - Macrophages, Minor Salivary Gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035260 Enhanced NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 1 "HPA035260: " "unprognostic (1.15e-1)" "unprognostic (2.09e-2)" "unprognostic (4.77e-2)" "unprognostic (2.77e-1)" "unprognostic (3.42e-2)" "unprognostic (1.73e-1)" "unprognostic (4.23e-2)" "unprognostic (2.71e-1)" "unprognostic (6.66e-2)" "unprognostic (2.06e-1)" "potential prognostic unfavorable (1.74e-4)" "unprognostic (2.20e-1)" "unprognostic (4.79e-2)" "unprognostic (9.65e-3)" "unprognostic (1.78e-1)" "unprognostic (1.80e-1)" "unprognostic (4.16e-2)" "unprognostic (7.06e-2)" "unprognostic (2.30e-2)" "unprognostic (1.87e-3)" "unprognostic (3.81e-1)" "unprognostic (1.66e-1)" "unprognostic (1.08e-2)" "unprognostic (7.25e-2)" "unprognostic (2.44e-2)" "unprognostic (2.35e-2)" "unprognostic (5.32e-2)" "unprognostic (2.44e-1)" "unprognostic (3.33e-2)" "unprognostic (1.66e-2)" "unprognostic (1.19e-1)" TRPM3 "GON-2, KIAA1616, LTRPC3" ENSG00000083067 "Transient receptor potential cation channel subfamily M member 3" Q9HCF6 9 70529060-71446904 "Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Calmodulin-binding, Ion channel" "Cataract, Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 36 "choroid plexus: 657.8" "Cell type enhanced" "Detected in many" "Astrocytes: 2692.6;Bergmann glia: 5527.6;Choroid plexus epithelial cells: 30653.7;Gonadotrophs: 3693.9;Lactotrophs: 3749.7;Retinal pigment epithelial cells: 11727.4" "Cell type enriched" "Detected in all" 4 "choroid plexus epithelial cell: 25353.9" "Cancer enhanced" "Detected in some" "Kidney Renal Clear Cell Carcinoma (TCGA): 3.1;Kidney Renal Papillary Cell Carcinoma (TCGA): 3.7" "Region enriched" "Detected in all" 15 "choroid plexus: 1433.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 5.1;Rhabdoid: 10.6" "Adipose visceral - Mesothelial cells, Kidney - Proximal tubular cells, Pancreas - Beta cells, Prostate - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA072650, HPA074393" Enhanced Uncertain Vesicles NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 101: Choroid plexus epithelial cells - Ion transport" Vesicles "HPA072650: , HPA074393: " "unprognostic (8.52e-3)" "unprognostic (1.97e-1)" "potential prognostic favorable (1.03e-9)" "unprognostic (1.07e-3)" "potential prognostic favorable (1.52e-4)" "unprognostic (5.71e-2)" "unprognostic (1.08e-1)" TRPM4 FLJ20041 ENSG00000130529 "Transient receptor potential cation channel subfamily M member 4" Q8TD43 19 49157741-49211836 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Adaptive immunity, Immunity, Ion transport, Transport" "Calmodulin-binding, Ion channel" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 119.1;Colonocytes: 189.8;Enteric transient amplifying cells: 91.5;Goblet cells: 129.5;Prostatic glandular cells: 93.7;Salivary duct cells: 89.1" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in all" 5 "Prostate Adenocarcinoma (TCGA): 154.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 8 "dendritic cells: 3.3;granulocytes: 2.8;monocytes: 4.3" "Low cancer specificity" "Detected in many" "Prostate - Prostate glandular cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041169 Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 77: Intestine - Digestion" "Cluster 12: Non-specific - Vasculature" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 65: Non-specific - Cell growth & division" 9 "Nucleoplasm, Plasma membrane" "HPA041169: " "unprognostic (4.49e-2)" "unprognostic (7.14e-2)" "unprognostic (1.37e-1)" "unprognostic (3.19e-1)" "unprognostic (9.51e-2)" "unprognostic (3.59e-2)" "unprognostic (9.12e-2)" "unprognostic (1.02e-3)" "unprognostic (5.64e-2)" "unprognostic (4.27e-2)" "unprognostic (1.26e-1)" "unprognostic (4.45e-3)" "potential prognostic favorable (4.08e-4)" "unprognostic (1.77e-1)" "unprognostic (4.52e-2)" "unprognostic (7.02e-2)" "unprognostic (9.86e-2)" "unprognostic (7.60e-2)" "unprognostic (9.68e-3)" "unprognostic (2.58e-2)" "unprognostic (1.42e-1)" "unprognostic (4.30e-3)" "unprognostic (4.07e-3)" "unprognostic (5.87e-2)" "unprognostic (4.66e-2)" "unprognostic (2.05e-1)" "unprognostic (1.17e-1)" "unprognostic (9.45e-2)" "unprognostic (3.45e-1)" "potential prognostic unfavorable (3.17e-4)" "unprognostic (2.77e-2)" TRPM5 "LTRPC5, MTR1" ENSG00000070985 "Transient receptor potential cation channel subfamily M member 5" Q9NZQ8 11 2404515-2444514 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 1.6;intestine: 3.1;pancreas: 2.3;seminal vesicle: 1.6" "Cell type enriched" "Detected in some" 12 "Tuft cells: 1256.6" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Pancreatic Adenocarcinoma (TCGA): 3.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "colorectal cancer: 1.0" "Pituitary gland - Somatotropes, Prostate - Urothelial cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 77: Intestine - Digestion" "Cluster 24: Non-specific - Unknown function" "Cluster 95: Tuft cells - Chemosensory signaling" 1 "unprognostic (2.90e-2)" "unprognostic (2.37e-1)" "unprognostic (8.37e-3)" TRPM6 "CHAK2, FLJ22628, HOMG, HSH" ENSG00000119121 "Transient receptor potential cation channel subfamily M member 6" Q9BX84 9 74722495-74888094 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Primary hypomagnesemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 15.6" "Cell type enhanced" "Detected in many" "Colonocytes: 219.6;Distal convoluted tubule cells: 1018.2;Endometrial glandular cells: 107.8;Endometrial luminal cells: 131.9;Enterocytes: 112.4;Neutrophil progenitors: 137.7;Neutrophils: 237.8;Renal connecting tubule cells: 276.4" "Group enriched" "Detected in many" 9 "endothelial cell: 369.5;oligodendrocyte: 117.3" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 4.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 23.2;neutrophil: 7.5" "Lineage enriched" "Detected in single" 44 "granulocytes: 23.2" "Cancer enhanced" "Detected in single" "Gallbladder cancer: 2.9" "Kidney - Intercalated cells, Skeletal muscle - Endothelial cells, Spleen - Neutrophils_2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 77: Intestine - Digestion" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" "unprognostic (1.44e-1)" "unprognostic (4.39e-1)" "unprognostic (5.32e-2)" "unprognostic (9.62e-2)" "unprognostic (1.25e-1)" "unprognostic (3.10e-1)" "potential prognostic favorable (2.86e-4)" "unprognostic (1.66e-1)" "unprognostic (1.92e-2)" "unprognostic (8.36e-2)" TRPM7 "CHAK1, LTRPC7, TRP-PLIK" ENSG00000092439 "Transient receptor potential cation channel subfamily M member 7" Q96QT4 15 50552473-50686797 "Disease related genes, Enzymes, Essential proteins, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Necrosis, Transport" "Calcium channel, Ion channel, Kinase, Serine/threonine-protein kinase, Transferase" "Amyotrophic lateral sclerosis, Disease variant, FDA approved drug targets, Neurodegeneration, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "parathyroid gland: 102.5" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 833.5;Choroid plexus epithelial cells: 504.9;Distal convoluted tubule cells: 2550.7;Retinal pigment epithelial cells: 763.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035522, HPA052173" Enhanced Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 11 "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA035522: , HPA052173: " "unprognostic (5.36e-2)" "unprognostic (5.19e-2)" "unprognostic (2.05e-1)" "unprognostic (4.12e-2)" "unprognostic (5.77e-2)" "unprognostic (3.61e-1)" "unprognostic (1.49e-1)" "unprognostic (2.28e-1)" "unprognostic (5.51e-2)" "unprognostic (2.17e-3)" "potential prognostic favorable (4.75e-4)" "unprognostic (2.20e-2)" "unprognostic (1.37e-1)" "unprognostic (3.34e-2)" "unprognostic (1.60e-1)" "unprognostic (2.72e-1)" "unprognostic (8.81e-2)" "unprognostic (2.28e-1)" "unprognostic (1.20e-2)" "unprognostic (6.87e-2)" "unprognostic (1.96e-1)" "unprognostic (3.79e-1)" "unprognostic (9.83e-3)" "unprognostic (4.01e-2)" "unprognostic (2.38e-2)" "unprognostic (4.12e-2)" "unprognostic (5.89e-3)" "unprognostic (1.52e-1)" "unprognostic (2.17e-1)" "unprognostic (4.70e-3)" "unprognostic (1.20e-1)" TRPM8 ENSG00000144481 "Transient receptor potential cation channel subfamily M member 8" Q7Z2W7 2 233917373-234019522 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sensory transduction, Transport" "Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 57 "liver: 29.4;prostate: 75.4" "Group enriched" "Detected in some" 5 "Hepatocytes: 64.2;Prostatic club cells: 104.9;Prostatic glandular cells: 178.5" "Cell type enhanced" "Detected in some" "cerebellar inhibitory: 9.5" "Cancer enriched" "Detected in some" 35 "Prostate Adenocarcinoma (TCGA): 151.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Kidney cancer: 6.3;Myeloma: 7.1;prostate cancer: 13.1;skin cancer: 15.8" "Prostate - Prostate glandular cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 46: Brainstem - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 1 "unprognostic (1.09e-1)" "unprognostic (3.28e-3)" "unprognostic (5.52e-2)" "validated prognostic favorable (3.92e-4)" "validated prognostic favorable (6.18e-4)" "unprognostic (1.40e-1)" "unprognostic (8.13e-2)" "potential prognostic unfavorable (8.66e-4)" "unprognostic (2.98e-2)" "unprognostic (5.16e-2)" TRPS1 "GC79, LGCR" ENSG00000104447 "Transcriptional repressor GATA binding 1" Q9UHF7 8 115408496-115809673 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "breast: 56.9" "Cell type enhanced" "Detected in many" "Adipocytes: 951.9;Astrocytes: 1204.8;Bergmann glia: 1533.6;Breast hormone-responsive cells: 1683.2;Breast secretory cells: 1051.5;Ependymal cells: 1106.5" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 7 "Breast Invasive Carcinoma (TCGA): 108.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 4.5" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in many" 4 "breast cancer: 67.7" "Heart muscle - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Outer root sheath cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060380, HPA071767" Enhanced Supported Nucleoplasm NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 30 Nucleoplasm "HPA060380: , HPA071767: " "unprognostic (1.23e-1)" "unprognostic (4.40e-2)" "unprognostic (1.41e-1)" "unprognostic (6.79e-3)" "unprognostic (4.03e-2)" "unprognostic (3.24e-2)" "unprognostic (2.63e-1)" "unprognostic (5.24e-1)" "unprognostic (1.48e-3)" "unprognostic (3.54e-3)" "unprognostic (5.06e-2)" "unprognostic (2.37e-1)" "unprognostic (4.20e-2)" "unprognostic (4.03e-1)" "unprognostic (6.88e-2)" "unprognostic (5.89e-2)" "unprognostic (1.47e-1)" "unprognostic (1.45e-1)" "unprognostic (7.01e-2)" "unprognostic (2.68e-3)" "validated prognostic unfavorable (2.72e-5)" "validated prognostic unfavorable (1.79e-4)" "unprognostic (5.55e-2)" "unprognostic (1.14e-1)" "unprognostic (1.93e-2)" "unprognostic (1.99e-1)" "unprognostic (8.74e-2)" "unprognostic (1.12e-1)" "unprognostic (4.66e-3)" "unprognostic (2.49e-1)" TRPT1 MGC11134 ENSG00000149743 "TRNA phosphotransferase 1" Q86TN4 11 64223799-64226254 "Enzymes, Predicted intracellular proteins" "tRNA processing" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 166.3" "Cell type enhanced" "Detected in all" "Early spermatids: 137.8;Esophageal apical cells: 127.8;Goblet cells: 95.5;Late primary spermatocytes: 182.0;Late spermatids: 100.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038705, HPA038706" Uncertain Approved Mitochondria NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 19: Astrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 70: Intestinal goblet cells - Mucin production" 1 Mitochondria "HPA038705: , HPA038706: " "unprognostic (3.29e-1)" "unprognostic (1.16e-1)" "unprognostic (7.63e-2)" "unprognostic (3.73e-2)" "unprognostic (1.59e-2)" "unprognostic (2.16e-2)" "potential prognostic unfavorable (9.60e-4)" "potential prognostic favorable (6.27e-4)" "unprognostic (1.36e-1)" "unprognostic (1.68e-2)" "unprognostic (2.38e-2)" "potential prognostic unfavorable (6.69e-4)" "potential prognostic favorable (8.89e-8)" "unprognostic (1.98e-2)" "unprognostic (1.39e-1)" "unprognostic (2.52e-2)" "unprognostic (4.24e-2)" "unprognostic (1.00e-1)" "unprognostic (1.87e-1)" "unprognostic (1.10e-2)" "unprognostic (4.88e-2)" "unprognostic (4.33e-3)" "unprognostic (4.63e-2)" "unprognostic (9.30e-2)" "unprognostic (3.35e-1)" "unprognostic (1.78e-1)" "unprognostic (1.67e-1)" "unprognostic (4.12e-1)" "unprognostic (3.20e-1)" "unprognostic (3.85e-1)" "unprognostic (1.30e-1)" TRPV1 VR1 ENSG00000196689 "Transient receptor potential cation channel subfamily V member 1" Q8NER1 17 3565444-3609411 "FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Calmodulin-binding, Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 21.8" "Cell type enhanced" "Detected in many" "Astrocytes: 19.8;Myonuclei: 25.5;Myosatellite cells: 21.8;Proximal tubule cells: 24.5;Rod photoreceptor cells: 25.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 70: Non-specific - Protein processing" "Cluster 11: White matter - Signal transduction" "Cluster 42: Non-specific - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" 5 "unprognostic (1.37e-2)" "unprognostic (1.06e-1)" "unprognostic (6.98e-2)" "unprognostic (1.05e-1)" "unprognostic (3.46e-2)" "unprognostic (5.90e-2)" "unprognostic (1.28e-1)" "unprognostic (1.84e-3)" "unprognostic (3.22e-1)" "unprognostic (1.50e-2)" "unprognostic (2.18e-2)" "unprognostic (1.28e-1)" "unprognostic (5.66e-3)" "potential prognostic favorable (1.07e-5)" "unprognostic (3.01e-1)" "unprognostic (1.44e-2)" "unprognostic (7.46e-2)" "unprognostic (8.89e-3)" "unprognostic (9.16e-2)" "potential prognostic favorable (8.59e-5)" "unprognostic (1.51e-2)" "unprognostic (2.21e-3)" "unprognostic (3.44e-2)" "unprognostic (1.53e-3)" "unprognostic (1.13e-1)" "unprognostic (8.17e-3)" "unprognostic (3.60e-1)" "unprognostic (1.30e-1)" "unprognostic (2.66e-1)" TRPV2 "VRL, VRL-1, VRL1" ENSG00000187688 "Transient receptor potential cation channel subfamily V member 2" Q9Y5S1 17 16415571-16437003 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "cDC: 30.7;Hematopoietic stem cells: 21.8;Hepatic stellate cells: 51.6;Hofbauer cells: 39.6;Macrophages: 34.8;Mast cells: 39.2;Melanocytes: 54.3;monocytes: 27.4;NK-cells: 37.9;pDCs: 34.1;Pericytes: 39.7;Syncytiotrophoblasts: 24.4;T-cells: 29.2;Vascular smooth muscle cells: 29.3" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 20.1;leukocyte: 37.1" "Cancer enriched" "Detected in all" 8 "Skin Cutaneous Melanoma (TCGA): 162.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "skin cancer: 81.4" "Breast - Endothelial cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044993 Uncertain Supported "Plasma membrane" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" "Plasma membrane" "HPA044993: " "unprognostic (5.80e-2)" "unprognostic (3.86e-2)" "unprognostic (1.28e-1)" "unprognostic (3.04e-2)" "unprognostic (1.70e-1)" "unprognostic (1.70e-1)" "unprognostic (1.84e-2)" "unprognostic (1.15e-1)" "unprognostic (4.35e-3)" "unprognostic (4.29e-3)" "potential prognostic unfavorable (6.43e-4)" "unprognostic (1.06e-2)" "unprognostic (1.07e-1)" "unprognostic (1.19e-2)" "unprognostic (2.82e-1)" "unprognostic (2.56e-1)" "unprognostic (4.42e-3)" "unprognostic (1.65e-2)" "unprognostic (1.49e-1)" "unprognostic (2.50e-1)" "unprognostic (1.51e-1)" "unprognostic (5.15e-3)" "unprognostic (7.47e-2)" "unprognostic (1.40e-1)" "unprognostic (4.06e-2)" "unprognostic (9.70e-3)" "unprognostic (7.27e-2)" "unprognostic (3.13e-2)" "unprognostic (7.89e-3)" "unprognostic (5.95e-2)" "unprognostic (1.60e-1)" TRPV3 VRL3 ENSG00000167723 "Transient receptor potential cation channel subfamily V member 3" Q8NET8 17 3510502-3557812 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Disease variant, FDA approved drug targets, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 4.9;skeletal muscle: 1.7;skin 1: 5.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 20.8;Colonocytes: 20.0;Enterocytes: 64.3;Foveolar cells: 14.5;Goblet cells: 13.2;Myonuclei: 30.6;Ocular epithelial cells: 53.8;Paneth cells: 15.5;Plasma cells: 34.0;Sertoli cells: 13.7;Suprabasal keratinocytes: 19.6" "Cell type enhanced" "Detected in many" "astrocyte: 10.0" "Cancer enhanced" "Detected in single" "Head and Neck Squamous Cell Carcinoma (TCGA): 2.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 3.0" "Colon - Enteric glia cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA069550 Approved "Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 77: Intestine - Digestion" "Cluster 34: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 78: Plasma cells - Antibody production & ER-stress response" "Plasma membrane" "Centrosome, Cytosol" "HPA069550: " "unprognostic (2.35e-2)" "unprognostic (1.01e-3)" "unprognostic (1.03e-2)" "unprognostic (5.07e-2)" "unprognostic (1.70e-3)" "unprognostic (3.99e-3)" TRPV4 "CMT2C, OTRPC4, TRP12, VR-OAC, VRL-2, VROAC" ENSG00000111199 "Transient receptor potential cation channel subfamily V member 4" Q9HBA0 12 109783087-109833406 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Calmodulin-binding, Ion channel" "Charcot-Marie-Tooth disease, Disease variant, Dwarfism, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 69.8" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 679.7;Esophageal apical cells: 207.7;Kupffer cells: 111.7;Proximal tubule cells: 156.7;Renal collecting duct principal cells: 107.8;Renal connecting tubule cells: 134.0;Respiratory basal cells: 86.6;Respiratory ciliated cells: 128.0;Retinal pigment epithelial cells: 106.6" "Cell type enriched" "Detected in some" 38 "choroid plexus epithelial cell: 456.4" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 12 "choroid plexus: 107.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 10.6" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Lung - Respiratory ciliated cells, Prostate - Prostate basal glandular cells, Skin - Eccrine sweat gland cells, Spleen - Macrophages, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Region enhanced" "Detected in single" "medulla oblongata: 1.2" HPA007150 Uncertain NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 2 "HPA007150: " "unprognostic (1.18e-1)" "unprognostic (7.68e-2)" "unprognostic (6.11e-2)" "unprognostic (4.88e-2)" "unprognostic (8.78e-3)" "unprognostic (2.11e-1)" "unprognostic (1.40e-2)" "unprognostic (1.54e-3)" "potential prognostic favorable (4.70e-6)" "unprognostic (8.75e-2)" "unprognostic (4.80e-3)" "unprognostic (1.95e-2)" "unprognostic (7.32e-2)" "unprognostic (5.65e-2)" "unprognostic (7.40e-2)" "unprognostic (7.63e-2)" "unprognostic (1.31e-3)" "unprognostic (3.84e-3)" "unprognostic (1.29e-1)" "unprognostic (1.13e-1)" "unprognostic (5.56e-2)" "unprognostic (2.36e-1)" "unprognostic (2.94e-3)" "unprognostic (1.94e-2)" "unprognostic (4.31e-2)" "unprognostic (2.21e-1)" "unprognostic (1.04e-2)" "unprognostic (5.01e-2)" TRPV5 "CaT2, ECAC1" ENSG00000127412 "Transient receptor potential cation channel subfamily V member 5" Q9NQA5 7 142908101-142933746 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Calmodulin-binding, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 1.6;kidney: 4.0" "Cell type enriched" "Detected in some" 5 "Renal connecting tubule cells: 155.3" "Cell type enriched" "Detected in some" 6 "oligodendrocyte: 24.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Minor Salivary Gland - Minor salivary glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA063175 Uncertain NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 66: Non-specific - Mitochondria" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 2 "HPA063175: " TRPV6 "CaT1, ECAC2" ENSG00000165125 "Transient receptor potential cation channel subfamily V member 6" Q9H1D0 7 142871208-142885745 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Calmodulin-binding, Ion channel" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 36.4;prostate: 22.1;salivary gland: 65.3" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 8.3;Early spermatids: 8.8;Epicardial cells: 15.9;Late spermatids: 16.0;Pancreatic duct cells: 17.8;Papillary tip epithelial cells: 19.7;Prostatic glandular cells: 17.9;Renal collecting duct principal cells: 28.1;Renal connecting tubule cells: 33.8;Salivary acinar cells: 14.7" "Cell type enriched" "Detected in some" 6 "oligodendrocyte: 10.1" "Cancer enriched" "Detected in many" 6 "Prostate Adenocarcinoma (TCGA): 52.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 7.9;prostate cancer: 11.5" "Adipose visceral - Mesothelial cells, Liver - Cholangiocytes, Pituitary gland - Lactotropes, Prostate - Prostate glandular cells, Testis - Late spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" HPA062864 Approved NA NA "Cluster 60: Stomach - Digestion" "Cluster 60: Prostate cancer - Unknown function" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 4 "HPA062864: " "unprognostic (2.76e-1)" "unprognostic (1.47e-1)" "unprognostic (8.52e-2)" "unprognostic (1.72e-2)" "unprognostic (7.08e-3)" "unprognostic (2.73e-1)" "unprognostic (1.61e-1)" "unprognostic (1.28e-1)" "unprognostic (1.60e-2)" "unprognostic (1.92e-1)" "unprognostic (3.74e-1)" "unprognostic (1.08e-2)" "unprognostic (1.61e-1)" TRRAP "PAF400, TR-AP, Tra1" ENSG00000196367 "Transformation/transcription domain associated protein" Q9Y4A5 7 98877933-99050831 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator" "Autism spectrum disorder, Cancer-related genes, Deafness, Disease variant, Intellectual disability, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054376 Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 39: Non-specific - Transcription" "Cluster 51: Secretory epithelial cells - Mixed function" 139 Nucleoplasm "Golgi apparatus" "HPA054376: " "unprognostic (6.28e-2)" "unprognostic (2.34e-2)" "unprognostic (6.02e-2)" "unprognostic (1.59e-2)" "unprognostic (4.52e-2)" "unprognostic (7.52e-2)" "unprognostic (3.36e-1)" "unprognostic (2.40e-1)" "unprognostic (3.63e-2)" "unprognostic (2.37e-3)" "potential prognostic favorable (1.11e-5)" "unprognostic (4.21e-2)" "unprognostic (1.29e-1)" "unprognostic (1.64e-1)" "unprognostic (5.93e-2)" "unprognostic (2.07e-1)" "unprognostic (6.44e-2)" "unprognostic (9.53e-2)" "unprognostic (2.17e-2)" "unprognostic (7.54e-3)" "unprognostic (3.82e-1)" "unprognostic (2.27e-1)" "unprognostic (1.36e-2)" "unprognostic (1.00e-1)" "unprognostic (2.17e-2)" "potential prognostic favorable (8.80e-4)" "unprognostic (6.72e-3)" "unprognostic (2.27e-1)" "unprognostic (1.88e-1)" "unprognostic (1.55e-2)" "unprognostic (3.01e-1)" TRUB1 PUS4 ENSG00000165832 "TruB pseudouridine synthase family member 1" Q8WWH5 10 114938195-114977676 "Enzymes, Predicted intracellular proteins" "mRNA processing, tRNA processing" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 75.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037914, HPA057552" Approved Approved Vesicles NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 52: Non-specific - Mitochondria" "Cluster 18: Adrenal cortex cells - Steroidogensis" 5 Vesicles "HPA037914: , HPA057552: " "unprognostic (6.82e-2)" "unprognostic (6.23e-2)" "unprognostic (8.44e-2)" "unprognostic (5.79e-2)" "unprognostic (3.24e-2)" "unprognostic (2.73e-1)" "unprognostic (1.01e-2)" "unprognostic (2.86e-3)" "unprognostic (2.62e-1)" "unprognostic (6.17e-2)" "potential prognostic favorable (5.66e-6)" "unprognostic (8.15e-2)" "unprognostic (6.48e-2)" "unprognostic (2.13e-2)" "unprognostic (2.25e-1)" "unprognostic (2.67e-2)" "unprognostic (2.01e-1)" "unprognostic (3.84e-3)" "unprognostic (1.49e-1)" "unprognostic (2.69e-1)" "unprognostic (3.59e-3)" "unprognostic (2.92e-2)" "unprognostic (6.92e-2)" "unprognostic (3.74e-2)" "unprognostic (5.13e-3)" "unprognostic (3.95e-1)" "unprognostic (2.13e-1)" "unprognostic (2.49e-2)" "unprognostic (2.33e-1)" "unprognostic (1.07e-1)" "unprognostic (1.93e-1)" TRUB2 CLONE24922 ENSG00000167112 "TruB pseudouridine synthase family member 2" O95900 9 128305159-128322447 "Enzymes, Predicted intracellular proteins" "mRNA processing, tRNA processing" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 76.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Prostate - Prostate basal glandular cells, Stomach - Mitotic cells (Stomach), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021211 Uncertain NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 76: Non-specific - Metabolism" "Cluster 6: Non-specific - Immune response" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 97: Non-specific - Cellular respiration" 68 "HPA021211: " "unprognostic (3.21e-2)" "unprognostic (5.07e-3)" "unprognostic (6.24e-2)" "unprognostic (1.47e-1)" "unprognostic (3.68e-1)" "unprognostic (1.73e-1)" "unprognostic (1.24e-1)" "unprognostic (3.19e-3)" "unprognostic (3.78e-1)" "unprognostic (1.19e-1)" "potential prognostic favorable (6.26e-5)" "unprognostic (1.10e-2)" "unprognostic (3.03e-3)" "unprognostic (6.05e-2)" "unprognostic (3.97e-2)" "unprognostic (3.99e-2)" "unprognostic (2.56e-1)" "unprognostic (3.33e-1)" "unprognostic (8.28e-3)" "unprognostic (2.26e-1)" "unprognostic (5.32e-1)" "unprognostic (1.51e-1)" "unprognostic (1.81e-1)" "unprognostic (4.90e-3)" "unprognostic (3.93e-3)" "unprognostic (3.19e-2)" "unprognostic (1.73e-1)" "unprognostic (5.28e-2)" "unprognostic (1.47e-1)" "unprognostic (3.03e-2)" "unprognostic (1.39e-2)" TSACC "C1orf182, SIP, SSTK-IP" ENSG00000163467 "TSSK6 activating cochaperone" Q96A04 1 156337314-156346995 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 379 "testis: 879.2" "Cell type enhanced" "Detected in many" "Early spermatids: 6460.8;Late primary spermatocytes: 7373.3;Late spermatids: 29125.0" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 16.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 8 "basophil: 15.2" "Lineage enriched" "Detected in many" 8 "granulocytes: 15.2" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA029897 Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 6: Testis - Spermatogenesis" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 6 "Nuclear bodies" Nucleoplasm "HPA029897: " "unprognostic (7.92e-2)" "unprognostic (7.82e-2)" "unprognostic (1.96e-3)" "unprognostic (2.01e-2)" "unprognostic (2.55e-2)" "unprognostic (9.99e-2)" "unprognostic (4.08e-1)" "potential prognostic unfavorable (1.23e-5)" "unprognostic (1.04e-2)" "unprognostic (1.34e-2)" "unprognostic (8.31e-2)" "unprognostic (2.44e-2)" "unprognostic (1.37e-1)" "unprognostic (1.47e-1)" "unprognostic (2.24e-1)" "unprognostic (9.62e-2)" "unprognostic (2.97e-3)" "unprognostic (1.78e-1)" "unprognostic (2.48e-1)" "unprognostic (9.24e-2)" "unprognostic (1.07e-1)" "unprognostic (1.11e-2)" TSBP1 "C6orf10, TSBP" ENSG00000204296 "Testis expressed basic protein 1" Q5SRN2 6 32288526-32371907 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 159 "testis: 33.0" "Cell type enhanced" "Detected in some" "Bergmann glia: 19.6;Brain excitatory neurons: 11.2;Brain inhibitory neurons: 9.9;Early spermatids: 90.9;Late primary spermatocytes: 63.3;Late spermatids: 27.0;Oligodendrocyte progenitor cells: 13.0;Other brain neurons: 19.5;Renal collecting duct intercalated cells: 12.1" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA047479, HPA057426" Approved Uncertain "Endoplasmic reticulum" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 14: Neurons - Synaptic function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 28: Astrocytes - Homeostasis & neuron support" "Endoplasmic reticulum" "HPA047479: , HPA057426: " TSC1 "hamartin, KIAA0243, LAM, TSC" ENSG00000165699 "TSC complex subunit 1" Q92574 9 132891348-132946874 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Chaperone "Cancer-related genes, Disease variant, Epilepsy, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 244.9;Late spermatids: 764.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011568, CAB012481, HPA074132" Supported Supported "Lipid droplets,Primary cilium transition zone,Basal body,Cytosol" NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 62 Cytosol "Lipid droplets, Primary cilium transition zone, Basal body" "CAB011568: , CAB012481: , HPA074132: " "unprognostic (1.88e-2)" "unprognostic (1.10e-2)" "unprognostic (2.34e-1)" "unprognostic (5.36e-2)" "unprognostic (1.41e-1)" "potential prognostic unfavorable (1.18e-5)" "unprognostic (2.68e-1)" "potential prognostic favorable (9.62e-4)" "unprognostic (3.42e-1)" "unprognostic (1.67e-1)" "validated prognostic favorable (4.30e-7)" "validated prognostic favorable (8.97e-6)" "unprognostic (2.07e-1)" "unprognostic (2.70e-3)" "unprognostic (8.87e-2)" "unprognostic (1.59e-1)" "unprognostic (8.72e-2)" "unprognostic (5.82e-2)" "unprognostic (3.64e-3)" "unprognostic (4.86e-2)" "unprognostic (2.13e-1)" "unprognostic (5.58e-2)" "unprognostic (1.72e-2)" "unprognostic (2.62e-1)" "unprognostic (8.58e-3)" "unprognostic (3.62e-2)" "unprognostic (1.56e-2)" "unprognostic (1.95e-2)" "unprognostic (2.84e-1)" "unprognostic (3.51e-2)" "unprognostic (4.77e-2)" TSC2 "LAM, PPP1R160, TSC4, tuberin" ENSG00000103197 "TSC complex subunit 2" P49815 16 2047967-2089491 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "GTPase activation" "Cancer-related genes, Disease variant, Epilepsy, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002225, HPA030409, HPA049679" Approved Enhanced Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 54: Non-specific - Transcription" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 55 Cytosol "CAB002225: , HPA030409: , HPA049679: " "unprognostic (2.58e-1)" "unprognostic (6.05e-2)" "unprognostic (1.08e-1)" "unprognostic (3.91e-1)" "unprognostic (5.77e-2)" "unprognostic (1.57e-1)" "unprognostic (4.99e-2)" "unprognostic (2.48e-2)" "unprognostic (2.26e-2)" "unprognostic (1.29e-1)" "potential prognostic favorable (2.15e-5)" "unprognostic (3.16e-3)" "unprognostic (3.95e-2)" "unprognostic (3.33e-1)" "unprognostic (4.94e-2)" "unprognostic (3.31e-1)" "unprognostic (8.56e-2)" "unprognostic (3.71e-2)" "unprognostic (6.01e-3)" "unprognostic (1.25e-1)" "unprognostic (7.43e-2)" "unprognostic (7.20e-2)" "unprognostic (1.15e-3)" "unprognostic (1.74e-1)" "unprognostic (7.78e-3)" "unprognostic (1.42e-1)" "unprognostic (1.04e-1)" "unprognostic (4.90e-2)" "unprognostic (2.25e-1)" "unprognostic (7.25e-3)" "unprognostic (2.50e-1)" TSC22D1 "MGC17597, TGFB1I4, TSC22" ENSG00000102804 "TSC22 domain family member 1" Q15714 13 44432143-44577147 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Choroid plexus epithelial cells: 2316.0;Late spermatids: 1684.1;Myonuclei: 1518.2;Platelets: 3505.7" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 2145.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 44.9" "Group enriched" "Detected in all" 5 "dendritic cells: 17.9;granulocytes: 44.9;NK-cells: 16.8" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" HPA077414 Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 17 "Nucleoplasm, Nuclear bodies" "HPA077414: " "unprognostic (6.82e-2)" "unprognostic (1.29e-2)" "unprognostic (7.65e-2)" "unprognostic (1.07e-2)" "unprognostic (1.48e-1)" "unprognostic (2.71e-2)" "unprognostic (6.41e-2)" "unprognostic (9.19e-2)" "unprognostic (2.75e-2)" "unprognostic (1.47e-2)" "validated prognostic favorable (1.66e-10)" "validated prognostic favorable (2.12e-6)" "unprognostic (1.56e-1)" "unprognostic (3.59e-2)" "unprognostic (1.19e-1)" "unprognostic (2.28e-1)" "unprognostic (3.25e-3)" "unprognostic (2.49e-1)" "unprognostic (2.85e-2)" "potential prognostic unfavorable (3.48e-4)" "unprognostic (2.32e-2)" "unprognostic (8.82e-3)" "unprognostic (1.15e-1)" "unprognostic (2.97e-2)" "unprognostic (4.16e-1)" "unprognostic (2.19e-1)" "unprognostic (1.00e-1)" "unprognostic (4.50e-2)" "unprognostic (4.30e-2)" "unprognostic (1.81e-2)" "unprognostic (2.63e-3)" TSC22D2 "KIAA0669, TILZ4a, TILZ4b, TILZ4c" ENSG00000196428 "TSC22 domain family member 2" O75157 3 150408298-150466422 "Predicted intracellular proteins, Transcription factors" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal convoluted tubule cells: 907.3;Ocular epithelial cells: 931.5;Urothelial cells: 653.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004926 Approved Approved Cytosol NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 53: Neurons - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 100: Stratified epithelial cells - Barrier functions" 2 Cytosol "HPA004926: " "unprognostic (1.65e-1)" "unprognostic (1.52e-2)" "unprognostic (8.64e-2)" "unprognostic (3.77e-3)" "unprognostic (9.91e-2)" "unprognostic (2.21e-1)" "unprognostic (2.61e-1)" "unprognostic (3.06e-1)" "unprognostic (2.77e-2)" "unprognostic (1.20e-1)" "unprognostic (1.90e-1)" "unprognostic (8.45e-2)" "unprognostic (4.31e-2)" "unprognostic (4.34e-2)" "unprognostic (2.49e-1)" "unprognostic (1.04e-3)" "unprognostic (4.49e-3)" "unprognostic (9.67e-2)" "unprognostic (3.48e-1)" "unprognostic (1.00e-1)" "potential prognostic unfavorable (9.84e-4)" "unprognostic (3.36e-3)" "potential prognostic unfavorable (3.87e-4)" "unprognostic (8.68e-2)" "unprognostic (1.09e-1)" "unprognostic (2.43e-2)" "unprognostic (4.35e-2)" "unprognostic (2.12e-3)" "unprognostic (1.57e-1)" "unprognostic (2.66e-2)" "unprognostic (2.16e-2)" TSC22D3 "DIP, DSIPI, GILZ, hDIP, TSC-22R" ENSG00000157514 "TSC22 domain family member 3" Q99576 X 107713221-107777342 "Predicted intracellular proteins, Transcription factors" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 975.6;Innate lymphoid cells: 1241.6;Mast cells: 1534.2;Neutrophils: 1719.0;Plasma cells: 1189.8;Platelets: 1434.1;T-cells: 1108.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Myeloma: 150.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001916, CAB034364" Approved Approved "Nuclear speckles,Golgi apparatus,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 44: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 23 Cytosol "Nuclear speckles, Golgi apparatus" "CAB034364: , HPA001916: " "unprognostic (3.05e-3)" "unprognostic (6.21e-3)" "unprognostic (9.68e-2)" "unprognostic (1.96e-3)" "unprognostic (1.98e-1)" "unprognostic (5.27e-3)" "unprognostic (6.88e-2)" "unprognostic (4.36e-3)" "unprognostic (1.81e-2)" "unprognostic (4.46e-1)" "unprognostic (3.54e-3)" "unprognostic (2.54e-2)" "unprognostic (1.74e-1)" "unprognostic (6.55e-3)" "potential prognostic favorable (1.80e-4)" "unprognostic (2.68e-3)" "unprognostic (8.05e-2)" "unprognostic (2.85e-2)" "unprognostic (1.80e-1)" "unprognostic (7.48e-2)" "unprognostic (2.72e-1)" "unprognostic (1.12e-1)" "unprognostic (3.18e-1)" "unprognostic (5.24e-2)" "unprognostic (1.60e-1)" "unprognostic (1.46e-2)" "unprognostic (4.51e-2)" "unprognostic (2.13e-3)" "unprognostic (4.51e-2)" "unprognostic (3.75e-1)" "unprognostic (1.97e-1)" TSC22D4 "THG-1, TILZ2" ENSG00000166925 "TSC22 domain family member 4" Q9Y3Q8 7 100463359-100479232 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "brain: 851.2" "Cell type enhanced" "Detected in many" "Astrocytes: 202.3;Bergmann glia: 246.2;Esophageal apical cells: 388.6;Müller glia: 441.2;Neutrophils: 194.7;Oligodendrocytes: 239.3;Retinal pigment epithelial cells: 289.9;Schwann cells: 227.3" "Cell type enhanced" "Detected in all" "astrocyte: 243.3;Bergmann glia: 345.9;committed oligodendrocyte precursor: 220.9;oligodendrocyte: 279.7" "Cancer enriched" "Detected in all" 6 "Glioblastoma Multiforme (TCGA): 667.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pancreas - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006757 Uncertain Approved Cytosol NA NA 81000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 11: Muller glia cells - Retinal homeostasis" 72 Cytosol "HPA006757: " "unprognostic (2.47e-2)" "unprognostic (6.02e-2)" "unprognostic (8.99e-2)" "unprognostic (3.40e-2)" "unprognostic (1.54e-3)" "unprognostic (7.93e-2)" "unprognostic (3.37e-2)" "unprognostic (1.12e-1)" "unprognostic (3.38e-1)" "unprognostic (2.57e-1)" "potential prognostic unfavorable (9.55e-4)" "unprognostic (4.33e-1)" "unprognostic (6.90e-2)" "potential prognostic unfavorable (2.51e-4)" "unprognostic (1.02e-1)" "unprognostic (1.64e-1)" "unprognostic (1.64e-1)" "unprognostic (2.38e-1)" "unprognostic (5.04e-2)" "unprognostic (8.94e-3)" "unprognostic (3.26e-1)" "unprognostic (3.89e-2)" "unprognostic (4.80e-3)" "unprognostic (1.59e-1)" "unprognostic (1.99e-1)" "unprognostic (1.34e-1)" "unprognostic (4.00e-2)" "unprognostic (3.19e-2)" "unprognostic (4.59e-2)" "unprognostic (1.36e-1)" "unprognostic (1.48e-1)" TSEN15 C1orf19 ENSG00000198860 "TRNA splicing endonuclease subunit 15" Q8WW01 1 184051651-184123978 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "mRNA processing, tRNA processing" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029237 Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 8: Non-specific - Secretory pathway" 30 Nucleoli Nucleoplasm "HPA029237: " "unprognostic (1.05e-1)" "unprognostic (3.59e-1)" "unprognostic (1.17e-1)" "unprognostic (1.16e-1)" "unprognostic (1.09e-1)" "unprognostic (1.91e-2)" "unprognostic (4.68e-2)" "unprognostic (7.87e-3)" "unprognostic (2.17e-2)" "unprognostic (8.40e-3)" "unprognostic (4.11e-3)" "unprognostic (4.03e-3)" "unprognostic (3.30e-2)" "potential prognostic unfavorable (1.25e-5)" "unprognostic (1.34e-2)" "unprognostic (1.24e-1)" "unprognostic (2.84e-1)" "unprognostic (2.79e-2)" "unprognostic (3.53e-2)" "unprognostic (1.03e-2)" "unprognostic (8.51e-3)" "unprognostic (3.77e-1)" "unprognostic (3.38e-2)" "unprognostic (2.60e-2)" "unprognostic (2.30e-1)" "unprognostic (2.48e-1)" "unprognostic (5.76e-2)" "unprognostic (2.22e-1)" "unprognostic (4.63e-2)" "unprognostic (1.60e-2)" "unprognostic (1.78e-1)" TSEN2 "MGC2776, SEN2, SEN2L" ENSG00000154743 "TRNA splicing endonuclease subunit 2" Q8NCE0 3 12484421-12541549 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "mRNA processing, tRNA processing" Lyase "Neurodegeneration, Pontocerebellar hypoplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 140.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027120, HPA027125, HPA027268" Approved Supported Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 65: Brain - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 89: Adipocytes - Lipid metabolism" 11 Nucleoplasm "Centrosome, Cytosol" "HPA027120: , HPA027125: , HPA027268: " "unprognostic (1.22e-2)" "unprognostic (2.40e-3)" "unprognostic (1.61e-1)" "unprognostic (4.24e-2)" "unprognostic (3.62e-3)" "unprognostic (6.99e-2)" "unprognostic (5.87e-2)" "unprognostic (3.02e-3)" "unprognostic (2.07e-1)" "unprognostic (6.95e-2)" "unprognostic (8.57e-2)" "unprognostic (2.23e-2)" "unprognostic (8.21e-3)" "unprognostic (1.37e-3)" "unprognostic (1.30e-1)" "unprognostic (4.21e-2)" "unprognostic (5.15e-2)" "unprognostic (2.15e-1)" "unprognostic (1.65e-2)" "unprognostic (7.26e-2)" "unprognostic (7.09e-3)" "unprognostic (3.32e-2)" "unprognostic (2.52e-1)" "unprognostic (7.79e-2)" "potential prognostic favorable (6.53e-4)" "unprognostic (2.70e-1)" "unprognostic (1.42e-1)" "unprognostic (1.71e-1)" "unprognostic (7.87e-3)" "unprognostic (2.20e-1)" "unprognostic (3.59e-3)" TSEN34 "LENG5, SEN34, SEN34L" ENSG00000170892 "TRNA splicing endonuclease subunit 34" Q9BSV6 19 54189938-54194536 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "mRNA processing, tRNA processing" Lyase "Disease variant, Neurodegeneration, Pontocerebellar hypoplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 7.4;Bergmann glia: 7.8;Ependymal cells: 8.8;Loop of henle epithelial cells: 6.5;Microglia: 6.4;Oligodendrocyte progenitor cells: 10.3;Oligodendrocytes: 6.9;Other brain neurons: 10.1;Papillary tip epithelial cells: 6.6;Renal collecting duct principal cells: 8.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "basophil: 5.0;eosinophil: 1.9;neutrophil: 4.9" "Lineage enriched" "Detected in single" 8 "granulocytes: 5.0" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (other), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041111, HPA048208" Approved Supported Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 48: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 98: Neurons - Neurotransmission & signaling" 5 Nucleoplasm "HPA041111: , HPA048208: " "unprognostic (6.33e-2)" "unprognostic (8.95e-2)" "unprognostic (3.73e-2)" "unprognostic (6.41e-2)" "unprognostic (6.84e-2)" "unprognostic (7.79e-3)" "unprognostic (2.10e-2)" "unprognostic (5.96e-2)" "unprognostic (9.22e-2)" "unprognostic (1.47e-1)" "unprognostic (1.32e-1)" "unprognostic (3.71e-1)" "unprognostic (2.06e-1)" "unprognostic (2.55e-3)" "unprognostic (6.56e-2)" "unprognostic (1.91e-1)" "potential prognostic unfavorable (2.61e-4)" "unprognostic (2.92e-2)" "unprognostic (1.19e-1)" "unprognostic (4.38e-2)" "unprognostic (2.59e-2)" "unprognostic (2.52e-2)" "unprognostic (4.59e-2)" "unprognostic (2.43e-1)" "unprognostic (6.21e-2)" "unprognostic (2.32e-1)" "unprognostic (8.60e-2)" "unprognostic (1.42e-1)" "unprognostic (2.88e-2)" "unprognostic (3.24e-1)" TSEN54 "SEN54, SEN54L" ENSG00000182173 "TRNA splicing endonuclease subunit 54" Q7Z6J9 17 75515944-75524735 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "mRNA processing, tRNA processing" "Disease variant, Neurodegeneration, Pontocerebellar hypoplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 90.0;Mast cells: 103.4;NK-cells: 81.6;T-cells: 77.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024543, HPA053097" Uncertain Approved Nucleoplasm NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 21 Nucleoplasm "HPA024543: , HPA053097: " "unprognostic (2.77e-2)" "unprognostic (9.93e-2)" "unprognostic (2.08e-1)" "unprognostic (3.87e-3)" "unprognostic (5.16e-3)" "unprognostic (1.62e-2)" "unprognostic (3.88e-1)" "potential prognostic favorable (7.69e-5)" "unprognostic (8.60e-2)" "unprognostic (1.55e-1)" "unprognostic (3.83e-3)" "unprognostic (2.91e-1)" "unprognostic (4.89e-2)" "potential prognostic unfavorable (3.24e-6)" "unprognostic (1.65e-3)" "unprognostic (5.50e-2)" "unprognostic (1.19e-1)" "unprognostic (1.01e-1)" "unprognostic (1.59e-1)" "unprognostic (3.90e-2)" "potential prognostic favorable (6.40e-4)" "unprognostic (7.07e-2)" "unprognostic (8.09e-2)" "unprognostic (4.93e-2)" "unprognostic (2.40e-1)" "unprognostic (2.28e-1)" "unprognostic (2.31e-1)" "unprognostic (3.26e-3)" "unprognostic (5.34e-1)" "unprognostic (1.66e-1)" "unprognostic (6.95e-2)" TSFM "EF-TS, EF-Tsmt" ENSG00000123297 "Ts translation elongation factor, mitochondrial" P43897 12 57782761-57808071 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Protein biosynthesis" "Elongation factor" "Cardiomyopathy, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 29.4;Early spermatids: 62.8;Epicardial cells: 106.9;Late spermatids: 39.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006204 Supported Nucleoplasm,Mitochondria NA NA 6200 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 76: Non-specific - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 38 Mitochondria Nucleoplasm "HPA006204: " "unprognostic (1.52e-2)" "unprognostic (2.69e-2)" "unprognostic (9.30e-2)" "unprognostic (2.10e-1)" "unprognostic (3.32e-2)" "unprognostic (5.27e-2)" "unprognostic (2.25e-1)" "potential prognostic favorable (8.00e-5)" "unprognostic (9.19e-3)" "unprognostic (5.08e-2)" "unprognostic (1.28e-3)" "unprognostic (8.39e-2)" "unprognostic (3.70e-2)" "unprognostic (1.81e-3)" "potential prognostic unfavorable (4.00e-4)" "unprognostic (1.22e-2)" "unprognostic (3.90e-3)" "unprognostic (6.80e-2)" "unprognostic (1.38e-1)" "unprognostic (4.19e-1)" "unprognostic (3.72e-1)" "unprognostic (1.71e-1)" "unprognostic (4.59e-2)" "unprognostic (5.48e-3)" "unprognostic (1.04e-1)" "unprognostic (5.44e-2)" "unprognostic (1.95e-1)" "unprognostic (3.04e-1)" "unprognostic (1.59e-1)" "unprognostic (1.89e-1)" "unprognostic (1.02e-1)" TSG101 "TSG10, VPS23" ENSG00000074319 "Tumor susceptibility 101" Q99816 11 18468336-18526951 "Cancer-related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Growth regulation, Host-virus interaction, Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 436.9;Neutrophils: 363.7;Oocytes: 580.2;Syncytiotrophoblasts: 407.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "CAB004283, HPA006161" Approved Supported "Nucleoli,Plasma membrane,Cytosol" NA NA 11000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 153 Cytosol "Nucleoli, Plasma membrane" "CAB004283: , HPA006161: " "unprognostic (2.26e-3)" "unprognostic (2.58e-1)" "unprognostic (1.65e-3)" "unprognostic (1.19e-1)" "unprognostic (1.55e-2)" "unprognostic (1.10e-1)" "unprognostic (1.01e-1)" "unprognostic (1.51e-2)" "unprognostic (7.11e-3)" "unprognostic (2.45e-1)" "potential prognostic favorable (1.74e-6)" "unprognostic (4.41e-3)" "unprognostic (7.25e-3)" "potential prognostic unfavorable (1.70e-4)" "unprognostic (6.64e-3)" "unprognostic (1.67e-3)" "unprognostic (1.65e-2)" "unprognostic (2.43e-1)" "unprognostic (8.15e-2)" "unprognostic (2.29e-1)" "unprognostic (1.96e-2)" "unprognostic (2.22e-3)" "unprognostic (5.64e-3)" "unprognostic (1.47e-1)" "unprognostic (4.17e-2)" "unprognostic (3.21e-1)" "unprognostic (1.63e-1)" "unprognostic (7.55e-2)" "unprognostic (2.73e-2)" "unprognostic (9.49e-2)" "unprognostic (4.80e-2)" TSGA10 "CEP4L, CT79" ENSG00000135951 "Testis specific 10" Q9BZW7 2 98997261-99154964 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "testis: 48.2" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 282.4;Early spermatids: 404.9;Ependymal cells: 770.1;Fallopian tube ciliated cells: 367.3;Late primary spermatocytes: 532.7;Late spermatids: 372.3;Respiratory ciliated cells: 441.0" "Cell type enhanced" "Detected in all" "ependymal cell: 806.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036879 Supported "Flagellar centriole" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 34: Ciliated cells - Cilia assembly & function" 55 "Flagellar centriole" "HPA036879: " "unprognostic (3.97e-1)" "unprognostic (4.34e-2)" "unprognostic (4.27e-3)" "unprognostic (1.20e-1)" "unprognostic (3.27e-1)" "unprognostic (2.90e-3)" "potential prognostic favorable (1.38e-4)" "unprognostic (1.08e-1)" "unprognostic (1.17e-2)" "unprognostic (3.12e-1)" "unprognostic (1.12e-1)" "unprognostic (4.67e-1)" "unprognostic (1.82e-3)" "unprognostic (1.82e-2)" "unprognostic (2.75e-1)" "unprognostic (3.02e-3)" "unprognostic (3.84e-2)" "unprognostic (8.77e-2)" "unprognostic (2.04e-2)" "unprognostic (2.72e-1)" TSGA10IP "FAM161C, FLJ32880" ENSG00000175513 "Testis specific 10 interacting protein" Q3SY00 11 65945480-65959966 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 12 "testis: 9.4" "Group enriched" "Detected in some" 7 "Early spermatids: 47.7;Late primary spermatocytes: 47.9;Late spermatids: 89.0;Melanocytes: 33.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Testicular Germ Cell Tumor (TCGA): 1.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA049510 Approved "Mid piece" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 83 "Mid piece" "HPA049510: " "unprognostic (2.35e-1)" TSGA13 ENSG00000213265 "Testis specific 13" Q96PP4 7 130668643-130687432 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 102 "testis: 12.3" "Cell type enriched" "Detected in some" 5 "Late spermatids: 384.8" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "Kidney Chromophobe (TCGA): 2.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA022968 Uncertain Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 1 Vesicles "Plasma membrane, Cytosol" "HPA022968: " "unprognostic (5.33e-2)" "unprognostic (4.23e-3)" TSHB ENSG00000134200 "Thyroid stimulating hormone subunit beta" P01222 1 115029826-115034302 "Disease related genes, Human disease related genes, Predicted secreted proteins" Hormone "Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 2474 "pituitary gland: 1603.2" "Cell type enhanced" "Detected in some" "Early spermatids: 1.3;Late spermatids: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pituitary gland - Thyrotropes" "Region enhanced" "Detected in single" "hypothalamus: 1.7" "Not detected" "Not detected" "CAB022202, HPA042681, CAB080112" Enhanced "Secreted to blood" Hormone NA NA 325000 "Cluster 20: Pituitary gland - Hormone signaling" "Cluster 49: Hindbrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "CAB022202: , CAB080112: , HPA042681: " TSHR LGR3 ENSG00000165409 "Thyroid stimulating hormone receptor" P16473 14 80954989-81146306 "Cancer-related genes, Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, Congenital hypothyroidism, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "thyroid gland: 257.0" "Cell type enhanced" "Detected in many" "Adipocytes: 60.0;Cardiomyocytes: 175.6;Epicardial cells: 147.8;Fibro-adipogenic progenitors: 90.2;Myonuclei: 46.3;Plasma cells: 75.7;Salivary acinar cells: 95.9" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in some" 107 "Thyroid Carcinoma (TCGA): 266.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "naive B-cell: 1.7;T-reg: 6.9" "Group enriched" "Detected in many" 5 "B-cells: 1.7;T-cells: 6.9" "Cancer enhanced" "Detected in some" "Myeloma: 10.0" "Minor Salivary Gland - Plasma cells, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in some" "Region enhanced" "Detected in single" "hypothalamus: 1.8" CAB000473 Approved "Intracellular and membrane" Receptor NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 33: Thyroid gland - Tissue development" "Cluster 9: Non-specific - Receptor signaling" "Cluster 59: Leukemia - T-cell receptor" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 15 "CAB000473: " "unprognostic (1.57e-2)" "unprognostic (3.33e-2)" "unprognostic (1.37e-2)" "unprognostic (8.50e-3)" "unprognostic (1.72e-1)" "unprognostic (3.95e-2)" "unprognostic (1.88e-2)" "unprognostic (6.52e-2)" "unprognostic (1.18e-1)" "unprognostic (1.77e-3)" "unprognostic (1.69e-1)" "unprognostic (1.00e-1)" TSHZ1 "NY-CO-33, SDCCAG33, TSH1" ENSG00000179981 "Teashirt zinc finger homeobox 1" Q6ZSZ6 18 75210755-75289950 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Corticotrophs: 197.0;Lactotrophs: 137.6;Peritubular myoid cells: 224.3;Podocytes: 181.2;Thyrotrophs: 163.5" "Cell type enhanced" "Detected in all" "eccentric medium spiny neuron: 476.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Testis - Peritubular cells" "Region enriched" "Detected in all" 5 "olfactory bulb: 115.6" "Low region specificity" "Detected in all" HPA006982 Approved Approved Nucleoplasm NA NA "Cluster 1: T-cells - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" Nucleoplasm "HPA006982: " "unprognostic (1.78e-2)" "unprognostic (3.23e-2)" "unprognostic (4.42e-1)" "unprognostic (1.74e-1)" "unprognostic (2.31e-1)" "unprognostic (4.90e-2)" "unprognostic (1.34e-1)" "unprognostic (1.74e-2)" "unprognostic (1.87e-3)" "unprognostic (2.88e-1)" "validated prognostic favorable (2.70e-6)" "validated prognostic favorable (1.50e-5)" "unprognostic (2.27e-2)" "unprognostic (1.68e-1)" "unprognostic (2.04e-1)" "unprognostic (1.20e-1)" "unprognostic (1.01e-1)" "unprognostic (2.50e-1)" "unprognostic (1.19e-1)" "unprognostic (1.41e-1)" "unprognostic (2.56e-1)" "unprognostic (2.92e-2)" "unprognostic (1.36e-1)" "unprognostic (3.10e-1)" "unprognostic (1.05e-1)" "unprognostic (5.67e-2)" "unprognostic (2.30e-1)" "unprognostic (1.54e-1)" "unprognostic (1.28e-1)" "potential prognostic unfavorable (9.78e-4)" "unprognostic (3.33e-2)" TSHZ2 "C20orf17, OVC10-2, TSH2, ZABC2, ZNF218" ENSG00000182463 "Teashirt zinc finger homeobox 2" Q9NRE2 20 52972358-53495330 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 2204.0;Fibro-adipogenic progenitors: 1839.7;Lacrimal acinar cells: 1160.4;Leydig cells: 1861.9;Ovarian stromal cells: 1156.5;Peritubular myoid cells: 2232.5;Respiratory basal cells: 1765.0;Respiratory secretory cells: 1367.6;Salivary acinar cells: 1461.3;Salivary duct cells: 1470.9;Thyrotrophs: 1604.3" "Cell type enhanced" "Detected in all" "deep-layer near-projecting: 2575.1;miscellaneous: 1434.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 3.0;T-reg: 2.4" "Lineage enriched" "Detected in single" 5 "T-cells: 3.0" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Lung - Fibroblasts_2, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" HPA038123 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 75: Ovary - Mixed function" "Cluster 22: Non-specific - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 15 "Golgi apparatus" Nucleoplasm "HPA038123: " "unprognostic (3.98e-2)" "unprognostic (1.29e-2)" "unprognostic (4.28e-2)" "unprognostic (5.68e-2)" "unprognostic (3.60e-2)" "unprognostic (1.31e-2)" "validated prognostic unfavorable (1.28e-4)" "validated prognostic unfavorable (7.86e-4)" "unprognostic (1.61e-1)" "unprognostic (4.91e-2)" "unprognostic (6.05e-2)" "unprognostic (5.29e-3)" "unprognostic (4.72e-1)" "unprognostic (2.75e-3)" "unprognostic (1.27e-2)" "unprognostic (1.37e-3)" "unprognostic (1.06e-1)" "unprognostic (7.82e-2)" "unprognostic (1.18e-2)" "potential prognostic unfavorable (7.35e-4)" "unprognostic (1.17e-1)" "unprognostic (4.09e-1)" "unprognostic (3.36e-2)" "unprognostic (6.76e-2)" "unprognostic (3.71e-3)" "unprognostic (2.70e-2)" "unprognostic (1.24e-1)" "potential prognostic unfavorable (2.29e-5)" "unprognostic (6.34e-2)" TSHZ3 "KIAA1474, TSH3, ZNF537" ENSG00000121297 "Teashirt zinc finger homeobox 3" Q63HK5 19 31149979-31349436 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 31.7" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 191.5;Decidual stromal cells: 130.7;Endometrial stromal cells: 208.8;Lactotrophs: 182.1;Leydig cells: 133.7;Myosatellite cells: 177.7;Ovarian stromal cells: 136.2;Podocytes: 120.8;Retinal bipolar cells: 114.5;Somatotrophs: 114.9" "Cell type enhanced" "Detected in all" "deep-layer near-projecting: 246.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 1.9" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Bone cancer: 21.1;Sarcoma: 13.6" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Adrenal gland - Fibroblasts, Heart muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008834, HPA071010" Approved Enhanced "Nucleoplasm,Plasma membrane" No No "Cluster 21: Neutrophils - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 108: Fibroblasts - ECM organization" 27 Nucleoplasm "Plasma membrane" "HPA008834: , HPA071010: " "unprognostic (1.39e-2)" "unprognostic (2.84e-1)" "unprognostic (2.12e-1)" "unprognostic (1.07e-1)" "unprognostic (2.88e-2)" "unprognostic (7.02e-2)" "unprognostic (2.15e-2)" "potential prognostic unfavorable (6.58e-4)" "unprognostic (4.93e-2)" "unprognostic (1.12e-1)" "unprognostic (1.65e-1)" "unprognostic (1.27e-1)" "unprognostic (4.47e-2)" "unprognostic (3.40e-2)" "unprognostic (2.73e-1)" "unprognostic (1.97e-3)" "unprognostic (1.73e-1)" "unprognostic (2.08e-1)" "potential prognostic unfavorable (5.27e-4)" "unprognostic (1.40e-1)" "unprognostic (6.74e-2)" "unprognostic (2.08e-1)" "unprognostic (1.30e-2)" "unprognostic (1.77e-1)" "unprognostic (2.97e-2)" "unprognostic (2.17e-1)" "unprognostic (1.04e-2)" "unprognostic (8.37e-2)" "unprognostic (9.59e-3)" "unprognostic (8.87e-2)" TSKS "PPP1R161, TSSKS" ENSG00000126467 "Testis specific serine kinase substrate" Q9UJT2 19 49739753-49763306 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 66 "testis: 115.8" "Group enriched" "Detected in many" 4 "Early spermatids: 1128.4;Late spermatids: 1393.1" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 3.8" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.3;Leukemia: 1.4" "Minor Salivary Gland - Fibroblasts, Prostate - Fibroblasts, Testis - Late spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA045729 Enhanced NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 79: Testis - Spermatogenesis" "Cluster 35: Non-specific - DNA binding" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 6 "HPA045729: " "unprognostic (1.91e-2)" "unprognostic (1.03e-1)" "unprognostic (1.57e-1)" TSKU "E2IG4, LRRC54, TSK" ENSG00000182704 "Tsukushi, small leucine rich proteoglycan" Q8WUA8 11 76782251-76798153 "Predicted secreted proteins" Neurogenesis "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 222.0" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 673.8" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 19.7;fibroblast: 26.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Skeletal muscle - Macrophages, Spleen - Fibroblasts_1, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA008164 Approved Approved "Nucleoplasm,Nuclear bodies" "Secreted to blood" "Developmental protein" NA NA 3800000 "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 23: Choroid plexus - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 93: Hepatocytes - Bile production & excretion" Nucleoplasm "Nuclear bodies" "HPA008164: " "unprognostic (1.67e-1)" "unprognostic (1.19e-2)" "unprognostic (1.58e-1)" "potential prognostic unfavorable (2.76e-4)" "unprognostic (1.33e-1)" "unprognostic (1.45e-1)" "unprognostic (1.37e-1)" "unprognostic (4.83e-3)" "unprognostic (2.10e-1)" "unprognostic (5.47e-3)" "potential prognostic unfavorable (1.23e-5)" "unprognostic (1.76e-3)" "potential prognostic unfavorable (9.27e-5)" "unprognostic (4.05e-1)" "unprognostic (1.85e-1)" "unprognostic (1.50e-3)" "unprognostic (3.99e-3)" "unprognostic (3.65e-1)" "unprognostic (1.25e-1)" "unprognostic (1.89e-2)" "unprognostic (1.05e-1)" "potential prognostic unfavorable (2.65e-4)" "unprognostic (2.84e-1)" "unprognostic (2.72e-2)" "unprognostic (1.40e-1)" "unprognostic (1.48e-1)" "unprognostic (3.92e-2)" "unprognostic (2.96e-2)" "unprognostic (2.96e-1)" "unprognostic (1.24e-2)" "unprognostic (4.48e-2)" TSLP ENSG00000145777 "Thymic stromal lymphopoietin" Q969D9 5 111070062-111078026 "FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 10.8;urinary bladder: 11.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 43.3;Breast secretory cells: 13.6;Early spermatids: 45.5;Esophageal basal cells: 34.1;Fibroblasts: 25.3;Late spermatids: 38.8;Ocular epithelial cells: 17.8;Pericytes: 36.8;Respiratory basal cells: 21.7;Suprabasal keratinocytes: 17.0" "Cell type enhanced" "Detected in some" "Bergmann glia: 2.3;fibroblast: 3.2;pericyte: 4.1;vascular associated smooth muscle cell: 2.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "thalamus: 2.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Heart muscle - Cardiomyocytes, Stomach - Fibroblasts" "Not detected" "Not detected" HPA056350 Uncertain "Golgi apparatus,Vesicles" "Secreted to blood" Cytokine NA NA 38400 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 39: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 17: Non-specific - RNA processing" "Golgi apparatus, Vesicles" "HPA056350: " "unprognostic (2.00e-1)" "unprognostic (3.84e-1)" "unprognostic (2.14e-1)" "unprognostic (6.83e-3)" "unprognostic (1.34e-1)" "unprognostic (4.59e-3)" "potential prognostic favorable (1.34e-4)" "unprognostic (9.35e-3)" "unprognostic (1.67e-1)" "unprognostic (8.36e-2)" "unprognostic (5.25e-2)" "unprognostic (9.30e-2)" TSN "BCLF-1, REHF-1, TRSLN" ENSG00000211460 Translin Q15631 2 121737103-121767853 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "DNA-binding, Endonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 224.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059561 Uncertain Supported "Nucleoplasm,Endoplasmic reticulum" NA NA 680000 "Cluster 25: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 19 "Nucleoplasm, Endoplasmic reticulum" "HPA059561: " "unprognostic (6.54e-2)" "unprognostic (1.34e-1)" "unprognostic (4.00e-2)" "unprognostic (9.66e-2)" "unprognostic (2.92e-2)" "unprognostic (6.87e-2)" "unprognostic (7.26e-2)" "unprognostic (6.24e-1)" "unprognostic (1.15e-1)" "unprognostic (1.87e-1)" "potential prognostic favorable (3.81e-4)" "unprognostic (4.78e-3)" "unprognostic (1.00e-1)" "unprognostic (1.15e-2)" "potential prognostic unfavorable (7.26e-4)" "unprognostic (1.33e-2)" "unprognostic (2.94e-2)" "unprognostic (1.02e-1)" "unprognostic (1.57e-1)" "unprognostic (1.74e-1)" "unprognostic (1.27e-1)" "unprognostic (1.51e-1)" "unprognostic (5.25e-2)" "unprognostic (5.49e-2)" "unprognostic (3.53e-1)" "unprognostic (3.49e-1)" "unprognostic (1.02e-1)" "unprognostic (1.11e-1)" "unprognostic (2.34e-2)" "unprognostic (2.95e-1)" "unprognostic (1.38e-1)" TSNARE1 FLJ31164 ENSG00000171045 "T-SNARE domain containing 1" Q96NA8 8 142212080-142403182 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074249 Approved Approved Cytosol NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 64: Non-specific - Transcription" "Cluster 53: Neurons - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 3 Cytosol "HPA074249: " "unprognostic (1.08e-1)" "unprognostic (2.15e-1)" "unprognostic (1.70e-1)" "unprognostic (1.09e-2)" "unprognostic (5.59e-2)" "unprognostic (3.39e-1)" "unprognostic (9.15e-2)" "unprognostic (1.09e-3)" "unprognostic (2.46e-3)" "unprognostic (1.58e-1)" "unprognostic (8.54e-3)" "unprognostic (1.90e-2)" "unprognostic (5.17e-2)" "unprognostic (2.41e-3)" "unprognostic (3.97e-2)" "potential prognostic favorable (1.48e-5)" "unprognostic (1.32e-1)" "unprognostic (1.18e-1)" "unprognostic (1.17e-1)" "unprognostic (8.56e-2)" "unprognostic (1.78e-2)" "unprognostic (4.62e-2)" "unprognostic (3.57e-2)" "unprognostic (1.59e-2)" "unprognostic (3.30e-1)" "unprognostic (3.79e-3)" "unprognostic (4.90e-2)" "unprognostic (1.45e-1)" "unprognostic (2.52e-1)" "unprognostic (6.05e-3)" "unprognostic (2.68e-1)" TSNAX "C3PO, TRAX" ENSG00000116918 "Translin associated factor X" Q99598 1 231528541-231566524 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 9 "Astrocytes: 29.0;Bergmann glia: 36.6;Brain excitatory neurons: 38.6;Brain inhibitory neurons: 34.8;Choroid plexus epithelial cells: 58.7;Ependymal cells: 36.3;Microglia: 81.9;Oligodendrocyte progenitor cells: 36.0;Oligodendrocytes: 55.4;Other brain neurons: 40.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 194.6" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024613, HPA031054, HPA031055, CAB034263" Approved Enhanced "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 21000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 45: Non-specific - Nuclear processes" "Cluster 22: Non-specific - Basic cellular functions" 52 Nucleoplasm "Golgi apparatus, Cytosol" "CAB034263: , HPA024613: , HPA031054: , HPA031055: " "unprognostic (1.67e-1)" "unprognostic (2.87e-2)" "unprognostic (9.89e-3)" "unprognostic (9.91e-3)" "unprognostic (2.03e-1)" "unprognostic (4.77e-2)" "unprognostic (2.66e-1)" "unprognostic (1.97e-1)" "unprognostic (1.34e-1)" "potential prognostic unfavorable (2.77e-4)" "potential prognostic favorable (7.95e-7)" "unprognostic (5.63e-2)" "unprognostic (8.76e-2)" "unprognostic (1.63e-2)" "unprognostic (1.15e-1)" "unprognostic (1.98e-1)" "unprognostic (2.85e-1)" "unprognostic (1.29e-1)" "unprognostic (3.48e-2)" "unprognostic (2.44e-1)" "potential prognostic unfavorable (9.38e-5)" "unprognostic (1.98e-1)" "unprognostic (9.61e-2)" "unprognostic (9.89e-2)" "unprognostic (1.25e-1)" "unprognostic (1.65e-2)" "unprognostic (1.12e-1)" "unprognostic (1.52e-1)" "unprognostic (1.94e-1)" "unprognostic (4.76e-3)" "unprognostic (7.81e-2)" TSNAXIP1 TXI1 ENSG00000102904 "Translin associated factor X interacting protein 1" Q2TAA8 16 67806765-67832148 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 8.1;testis: 19.7" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 34.7;Early primary spermatocytes: 35.0;Early spermatids: 102.7;Endometrial ciliated cells: 52.4;Ependymal cells: 63.1;Epicardial cells: 43.2;Epididymal efferent duct ciliated cells: 41.1;Fallopian tube ciliated cells: 71.5;Late primary spermatocytes: 123.8;Late spermatids: 286.4;Respiratory ciliated cells: 76.7" "Cell type enhanced" "Detected in all" "ependymal cell: 66.6" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 3.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA053516 Approved Nucleoplasm,Cytosol NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 4 Nucleoplasm Cytosol "HPA053516: " "unprognostic (7.34e-3)" "unprognostic (1.29e-1)" "unprognostic (1.19e-1)" "unprognostic (7.99e-2)" "unprognostic (1.55e-2)" "unprognostic (7.05e-3)" "unprognostic (1.85e-1)" "unprognostic (4.57e-1)" "unprognostic (3.43e-2)" TSPAN1 "NET-1, TSPAN-1" ENSG00000117472 "Tetraspanin 1" O60635 1 46175073-46185962 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 556.4;kidney: 233.4" "Cell type enhanced" "Detected in many" "Colonocytes: 1953.6;Conjunctival goblet cells: 1777.7;Enterocytes: 501.0;Goblet cells: 876.3;Late spermatids: 1580.0;Prostatic hillock cells: 514.4;Respiratory ciliated cells: 1602.3;Respiratory deuterosomal cells: 859.4;Respiratory secretory cells: 1004.9;Salivary duct cells: 1518.3" "Cell type enhanced" "Detected in many" "deep-layer near-projecting: 4.3;upper rhombic lip: 5.0" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 882.7" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 57 "plasmacytoid DC: 5.6" "Lineage enriched" "Detected in single" 57 "dendritic cells: 5.6" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 217.9" "Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Stomach - Gastric mucous cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA011909 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 3 "Nucleoplasm, Vesicles" "HPA011909: " "unprognostic (3.87e-2)" "unprognostic (1.60e-1)" "unprognostic (7.83e-2)" "unprognostic (1.35e-1)" "unprognostic (3.53e-2)" "unprognostic (1.15e-3)" "unprognostic (4.75e-2)" "unprognostic (1.23e-1)" "unprognostic (4.02e-2)" "potential prognostic favorable (7.30e-7)" "unprognostic (1.19e-1)" "unprognostic (1.66e-3)" "unprognostic (1.78e-2)" "unprognostic (7.95e-2)" "unprognostic (4.46e-2)" "unprognostic (9.81e-2)" "unprognostic (3.61e-2)" "unprognostic (1.48e-2)" "unprognostic (1.72e-1)" "unprognostic (3.09e-1)" "unprognostic (2.39e-3)" "unprognostic (1.38e-2)" "unprognostic (1.58e-1)" "unprognostic (2.64e-1)" "potential prognostic unfavorable (3.06e-4)" "unprognostic (1.56e-2)" "unprognostic (2.13e-1)" "unprognostic (9.55e-2)" "unprognostic (4.28e-2)" "unprognostic (3.52e-1)" TSPAN10 OCSP ENSG00000182612 "Tetraspanin 10" 17 81637171-81648754 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "skin 1: 1.5" "Cell type enriched" "Detected in many" 11 "Retinal pigment epithelial cells: 379.4" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 5.6" "Cancer enriched" "Detected in many" 12 "Skin Cutaneous Melanoma (TCGA): 139.8" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "skin cancer: 28.3" "Region enriched" "Detected in single" 4 "olfactory bulb: 1.3" "Low region specificity" "Detected in all" NA NA "Cluster 58: Skin - Keratinization" "Cluster 35: Non-specific - DNA binding" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" "unprognostic (1.20e-1)" "unprognostic (4.02e-2)" "potential prognostic favorable (1.79e-4)" "unprognostic (1.02e-1)" "unprognostic (2.85e-1)" "unprognostic (1.90e-2)" "unprognostic (1.72e-2)" "validated prognostic unfavorable (6.69e-5)" "validated prognostic unfavorable (3.40e-4)" "unprognostic (5.91e-2)" "unprognostic (1.46e-2)" "unprognostic (5.88e-2)" "unprognostic (5.80e-2)" "unprognostic (2.39e-2)" "unprognostic (7.42e-2)" "unprognostic (4.45e-2)" "unprognostic (2.60e-3)" "unprognostic (3.56e-1)" "unprognostic (2.67e-2)" "unprognostic (2.12e-1)" "unprognostic (8.80e-2)" "unprognostic (3.31e-1)" TSPAN11 ENSG00000110900 "Tetraspanin 11" A1L157 12 30926428-30996602 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 22.7" "Cell type enhanced" "Detected in many" "Bergmann glia: 124.3;Epicardial cells: 20.5;Epididymal efferent duct ciliated cells: 19.3;Late spermatids: 20.0;Lymphatic endothelial cells: 32.2;Oligodendrocyte progenitor cells: 50.7;Respiratory ciliated cells: 35.4;Schwann cells: 34.9;Tuft cells: 34.6" "Group enriched" "Detected in many" 5 "Bergmann glia: 131.3;oligodendrocyte precursor cell: 53.2" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 16.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 11.3;Neuroblastoma: 12.5;testis cancer: 10.3" "Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Minor Salivary Gland - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA066789 Approved Vesicles NA NA "Cluster 77: Intestine - Digestion" "Cluster 15: Non-specific - Transcription" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" Vesicles "HPA066789: " "unprognostic (3.24e-1)" "unprognostic (6.44e-3)" "unprognostic (2.11e-2)" "unprognostic (4.75e-2)" "unprognostic (4.74e-2)" "unprognostic (2.67e-1)" "unprognostic (1.73e-1)" "unprognostic (3.79e-2)" "unprognostic (4.60e-3)" "unprognostic (4.57e-3)" "unprognostic (6.40e-2)" "unprognostic (1.52e-1)" "potential prognostic favorable (1.35e-4)" "unprognostic (1.62e-1)" "unprognostic (3.09e-1)" "unprognostic (8.99e-2)" "unprognostic (2.61e-2)" "unprognostic (1.65e-2)" "unprognostic (1.41e-1)" "unprognostic (3.84e-2)" "unprognostic (8.80e-2)" "unprognostic (4.09e-2)" "unprognostic (1.84e-3)" "unprognostic (3.36e-2)" "unprognostic (9.14e-2)" "unprognostic (2.78e-3)" "unprognostic (1.33e-1)" TSPAN12 "NET-2, TM4SF12" ENSG00000106025 "Tetraspanin 12" O95859 7 120787320-120858402 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Angiogenesis "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 85.5" "Cell type enhanced" "Detected in many" "Breast lactating cells: 173.7;Endometrial luminal cells: 184.2;Enterocytes: 124.7;Parietal cells: 113.1;Salivary acinar cells: 107.7" "Cell type enhanced" "Detected in many" "midbrain-derived inhibitory: 62.5" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 115.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Skin - Endothelial cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051570, HPA058244" Uncertain Approved Vesicles,Microtubules NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 23 Microtubules Vesicles "HPA051570: , HPA058244: " "unprognostic (3.34e-1)" "unprognostic (7.43e-2)" "unprognostic (2.86e-1)" "unprognostic (2.49e-2)" "unprognostic (7.34e-2)" "unprognostic (1.77e-1)" "unprognostic (1.97e-1)" "unprognostic (1.90e-2)" "unprognostic (1.65e-2)" "unprognostic (1.20e-1)" "validated prognostic favorable (1.56e-8)" "validated prognostic favorable (1.91e-4)" "unprognostic (1.90e-1)" "unprognostic (7.56e-2)" "unprognostic (8.71e-2)" "unprognostic (4.00e-2)" "unprognostic (2.76e-1)" "unprognostic (4.34e-1)" "unprognostic (6.27e-2)" "unprognostic (4.06e-1)" "unprognostic (2.68e-2)" "unprognostic (4.42e-2)" "unprognostic (4.82e-3)" "unprognostic (1.62e-1)" "unprognostic (1.13e-2)" "unprognostic (9.87e-3)" "unprognostic (1.52e-1)" "unprognostic (1.09e-1)" "unprognostic (1.26e-1)" "unprognostic (3.35e-2)" "unprognostic (6.32e-3)" TSPAN13 "NET-6, TM4SF13" ENSG00000106537 "Tetraspanin 13" O95857 7 16753755-16784536 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 512.6;Conjunctival goblet cells: 413.6;Cytotrophoblasts: 376.2;Gastric progenitor cells: 381.9;Goblet cells: 377.1;Pancreatic acinar cells: 264.5;pDCs: 290.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 99.9;plasmacytoid DC: 232.1" "Group enriched" "Detected in many" 42 "B-cells: 99.9;dendritic cells: 232.1" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Alveolar cells type 1, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Lactotropes, Skeletal muscle - Endothelial cells, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007426 Uncertain Uncertain Nucleoplasm NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 60: Stomach - Digestion" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 27: Breast cancer - Unknown function" "Cluster 70: Intestinal goblet cells - Mucin production" 1 Nucleoplasm "HPA007426: " "unprognostic (1.78e-2)" "unprognostic (1.56e-1)" "unprognostic (1.13e-1)" "unprognostic (4.94e-3)" "unprognostic (1.66e-1)" "unprognostic (4.24e-2)" "potential prognostic unfavorable (1.01e-5)" "unprognostic (1.92e-1)" "unprognostic (3.42e-2)" "unprognostic (1.86e-1)" "unprognostic (3.33e-2)" "unprognostic (1.29e-1)" "unprognostic (9.85e-3)" "potential prognostic unfavorable (4.68e-4)" "unprognostic (8.46e-3)" "unprognostic (3.44e-1)" "unprognostic (1.75e-1)" "unprognostic (1.01e-1)" "unprognostic (1.13e-1)" "unprognostic (5.87e-3)" "unprognostic (1.21e-2)" "unprognostic (2.28e-1)" "unprognostic (2.01e-1)" "unprognostic (2.46e-1)" "unprognostic (1.20e-1)" "potential prognostic unfavorable (9.54e-4)" "unprognostic (2.69e-2)" "unprognostic (4.45e-2)" "unprognostic (4.76e-1)" "unprognostic (8.04e-3)" "unprognostic (2.48e-1)" TSPAN14 "DC-TM4F2, MGC11352, TM4SF14" ENSG00000108219 "Tetraspanin 14" Q8NG11 10 80454265-80533124 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 310.5;Kupffer cells: 299.3;Neutrophils: 322.5;Prostatic hillock cells: 245.5" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 208.3;endothelial cell: 234.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast), Heart muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014773, HPA057174" Uncertain Supported Vesicles NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 2 Vesicles "HPA014773: , HPA057174: " "unprognostic (3.16e-2)" "unprognostic (7.69e-2)" "unprognostic (1.03e-1)" "unprognostic (1.44e-1)" "unprognostic (5.04e-1)" "unprognostic (7.79e-2)" "unprognostic (6.33e-2)" "unprognostic (1.29e-2)" "unprognostic (2.73e-1)" "unprognostic (5.17e-2)" "potential prognostic favorable (1.14e-6)" "unprognostic (9.29e-3)" "unprognostic (3.81e-3)" "unprognostic (1.77e-2)" "unprognostic (3.92e-1)" "unprognostic (2.11e-1)" "unprognostic (6.92e-2)" "unprognostic (1.52e-1)" "unprognostic (8.29e-2)" "unprognostic (1.29e-1)" "unprognostic (1.30e-1)" "unprognostic (3.40e-3)" "unprognostic (8.98e-3)" "unprognostic (4.41e-2)" "unprognostic (1.62e-1)" "unprognostic (1.03e-1)" "unprognostic (1.87e-1)" "unprognostic (1.54e-1)" "unprognostic (3.00e-1)" "unprognostic (8.18e-2)" "unprognostic (1.49e-1)" TSPAN15 "NET-7, TM4SF15" ENSG00000099282 "Tetraspanin 15" O95858 10 69451465-69507666 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 98.0" "Cell type enhanced" "Detected in many" "Adipocytes: 123.4;Alveolar cells type 1: 145.7;Colonocytes: 127.4;Foveolar cells: 149.3;Oligodendrocytes: 134.7;Urothelial cells: 230.1" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 110.3;oligodendrocyte: 150.6;upper rhombic lip: 71.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "MAIT T-cell: 19.5" "Lineage enriched" "Detected in many" 6 "T-cells: 19.5" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044657, HPA071160" Approved Approved "Nuclear bodies,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 30: White matter - Myelination" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 69: Urothelial cells - Basic cellular functions" 131 "Nuclear bodies, Plasma membrane" "Vesicles, Cytosol" "HPA044657: , HPA071160: " "unprognostic (1.90e-1)" "unprognostic (2.36e-1)" "unprognostic (1.64e-1)" "unprognostic (1.97e-2)" "unprognostic (2.09e-1)" "unprognostic (6.78e-2)" "unprognostic (1.59e-1)" "unprognostic (1.13e-2)" "unprognostic (2.33e-2)" "unprognostic (1.89e-1)" "unprognostic (2.67e-2)" "unprognostic (3.52e-1)" "unprognostic (1.02e-1)" "potential prognostic unfavorable (2.83e-4)" "unprognostic (3.51e-1)" "unprognostic (1.81e-1)" "unprognostic (4.90e-2)" "unprognostic (8.90e-2)" "unprognostic (2.65e-1)" "unprognostic (1.70e-1)" "unprognostic (6.96e-3)" "unprognostic (9.42e-3)" "unprognostic (7.96e-2)" "unprognostic (1.40e-1)" "unprognostic (3.47e-2)" "unprognostic (1.88e-3)" "unprognostic (7.41e-2)" "unprognostic (2.98e-2)" "unprognostic (4.88e-2)" "unprognostic (7.34e-3)" "unprognostic (1.01e-1)" TSPAN16 "TM-8, TM4-B, TM4SF16" ENSG00000130167 "Tetraspanin 16" Q9UKR8 19 11296139-11326996 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 26 "testis: 124.5" "Cell type enriched" "Detected in many" 7 "Late spermatids: 8553.0" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 11 "basophil: 16.6;eosinophil: 19.2;neutrophil: 37.6" "Lineage enriched" "Detected in many" 17 "granulocytes: 37.6" "Not detected" "Not detected" "Spleen - Neutrophils_2, Testis - Late spermatids" "Not detected" "Not detected" HPA076551 Enhanced Approved "Plasma membrane" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 23: Testis - Spermatogenesis" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 2 "Plasma membrane" "HPA076551: " TSPAN17 "FBX23, FBXO23, TM4SF17" ENSG00000048140 "Tetraspanin 17" Q96FV3 5 176647387-176659054 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 72.7;Esophageal apical cells: 44.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Pituitary gland - Corticotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030447 Approved NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 51: Neurons - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" "HPA030447: " "unprognostic (2.75e-1)" "unprognostic (5.12e-3)" "unprognostic (2.21e-1)" "unprognostic (1.34e-1)" "unprognostic (7.47e-2)" "unprognostic (7.62e-2)" "unprognostic (5.86e-2)" "unprognostic (6.00e-1)" "unprognostic (3.62e-2)" "potential prognostic unfavorable (3.23e-5)" "unprognostic (1.35e-1)" "unprognostic (2.45e-2)" "unprognostic (1.33e-2)" "potential prognostic unfavorable (5.02e-4)" "unprognostic (3.24e-1)" "unprognostic (1.58e-1)" "unprognostic (5.12e-2)" "unprognostic (3.13e-2)" "unprognostic (1.78e-1)" "unprognostic (7.35e-2)" "unprognostic (1.75e-3)" "unprognostic (1.07e-1)" "unprognostic (1.24e-1)" "unprognostic (1.04e-1)" "unprognostic (1.86e-2)" "unprognostic (5.59e-2)" "unprognostic (1.56e-1)" "unprognostic (1.31e-1)" "unprognostic (1.44e-1)" "unprognostic (2.98e-2)" "unprognostic (7.13e-2)" TSPAN18 TSPAN ENSG00000157570 "Tetraspanin 18" Q96SJ8 11 44726465-44932423 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 78.2" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 86.6;Brain excitatory neurons: 42.2;Cardiomyocytes: 61.0;Early spermatids: 62.4;Lymphatic endothelial cells: 118.2;Medullary thymic epithelial cells: 74.4;Megakaryocytes: 55.6;Platelets: 167.9;Proximal tubule cells: 77.0;Smooth muscle cells: 50.8;Vascular endothelial cells: 102.8" "Cell type enhanced" "Detected in many" "fibroblast: 100.4;hippocampal CA4: 214.2;midbrain-derived inhibitory: 134.2;upper rhombic lip: 113.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Neuroblastoma: 31.1;testis cancer: 91.9" "Breast - Endothelial cells, Colon - Smooth muscle cells, Kidney - Proximal tubular cells, Liver - Vascular endothelial cells, Prostate - Smooth muscle cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 35: Non-specific - Mixed function" "Cluster 35: Non-specific - DNA binding" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 11 "unprognostic (3.14e-2)" "unprognostic (3.84e-1)" "unprognostic (1.45e-1)" "unprognostic (1.16e-1)" "unprognostic (1.99e-1)" "unprognostic (1.54e-1)" "unprognostic (6.33e-2)" "unprognostic (2.57e-1)" "unprognostic (7.80e-2)" "unprognostic (2.16e-1)" "validated prognostic favorable (1.11e-7)" "validated prognostic favorable (1.27e-4)" "unprognostic (4.93e-3)" "unprognostic (2.44e-1)" "unprognostic (2.53e-3)" "unprognostic (1.56e-1)" "unprognostic (1.42e-2)" "unprognostic (1.90e-3)" "unprognostic (3.38e-3)" "unprognostic (8.30e-2)" "potential prognostic unfavorable (6.10e-4)" "unprognostic (7.16e-2)" "unprognostic (1.25e-1)" "unprognostic (1.25e-1)" "unprognostic (1.52e-1)" "unprognostic (4.79e-3)" "unprognostic (8.22e-2)" "unprognostic (8.71e-3)" "unprognostic (1.78e-1)" "unprognostic (8.24e-2)" "unprognostic (1.69e-1)" TSPAN19 ENSG00000231738 "Tetraspanin 19" P0C672 12 85014311-85036277 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "retina: 4.0;testis: 4.1" "Cell type enriched" "Detected in some" 5 "Respiratory ciliated cells: 447.1" "Cell type enhanced" "Detected in many" "ependymal cell: 14.8" "Cancer enhanced" "Detected in some" "Lung Adenocarcinoma (TCGA): 2.4;Prostate Adenocarcinoma (TCGA): 2.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in single" "Adrenal gland - Adrenal medulla cells, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in some" HPA057066 Uncertain NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 65: Non-specific - Unknown function" "Cluster 107: Ciliated cells - Cilia assembly & function" "HPA057066: " "unprognostic (2.39e-1)" "unprognostic (2.79e-2)" "unprognostic (5.10e-2)" "unprognostic (2.41e-1)" "unprognostic (1.75e-1)" "unprognostic (2.01e-1)" "unprognostic (3.63e-3)" TSPAN2 "FLJ12082, TSN2, TSPAN-2" ENSG00000134198 "Tetraspanin 2" O60636 1 115048011-115089503 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 48.1" "Cell type enhanced" "Detected in many" "Neutrophil progenitors: 204.9;Neutrophils: 169.3;Pancreatic islet cells: 84.8;Platelets: 57.7;Podocytes: 313.1;Smooth muscle cells: 178.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 109.9;eosinophil: 56.0;neutrophil: 110.4;NK-cell: 86.6" "Group enriched" "Detected in many" 4 "granulocytes: 110.4;NK-cells: 86.6" "Cancer enhanced" "Detected in many" "Kidney cancer: 38.9" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Smooth muscle cells, Breast - Breast myoepithelial cells, Lung - Smooth muscle cells, Pituitary gland - Thyrotropes, Prostate - Smooth muscle cells, Spleen - Neutrophils_2" "Region enhanced" "Detected in all" "white matter: 842.8" "Low region specificity" "Detected in all" "HPA015640, HPA073306" Uncertain Enhanced Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 49: Hindbrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 60 Nucleoplasm "HPA015640: , HPA073306: " "unprognostic (1.19e-1)" "unprognostic (1.98e-2)" "unprognostic (2.50e-1)" "unprognostic (2.45e-2)" "unprognostic (3.26e-1)" "unprognostic (3.43e-3)" "potential prognostic unfavorable (8.97e-4)" "unprognostic (2.54e-2)" "unprognostic (2.67e-1)" "unprognostic (5.71e-3)" "unprognostic (1.10e-1)" "unprognostic (1.20e-2)" "unprognostic (1.37e-1)" "unprognostic (1.04e-1)" "unprognostic (2.69e-2)" "unprognostic (4.54e-3)" "unprognostic (1.87e-1)" "unprognostic (2.21e-2)" "unprognostic (1.26e-1)" "unprognostic (1.45e-1)" "unprognostic (2.83e-1)" "unprognostic (1.89e-1)" "unprognostic (1.30e-1)" "unprognostic (5.30e-2)" "unprognostic (1.64e-1)" "unprognostic (2.42e-3)" "unprognostic (2.54e-2)" TSPAN3 "TM4-A, TM4SF8, TSPAN-3" ENSG00000140391 "Tetraspanin 3" O60637 15 77041404-77083984 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 421.3;Colonocytes: 471.7;Fallopian tube ciliated cells: 478.0;Müller glia: 421.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "memory B-cell: 482.8;naive B-cell: 490.1;plasmacytoid DC: 313.6" "Group enriched" "Detected in all" 5 "B-cells: 490.1;dendritic cells: 313.6" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Lung - Alveolar cells type 2, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015996 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 21: Non-specific - Metabolism" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 15 "Nucleoplasm, Golgi apparatus" "HPA015996: " "unprognostic (3.63e-2)" "unprognostic (3.05e-2)" "unprognostic (3.65e-1)" "unprognostic (3.96e-2)" "unprognostic (1.92e-1)" "unprognostic (1.16e-1)" "unprognostic (2.27e-1)" "unprognostic (8.77e-3)" "unprognostic (8.46e-2)" "unprognostic (1.99e-2)" "unprognostic (2.79e-3)" "unprognostic (7.65e-3)" "unprognostic (4.60e-1)" "unprognostic (3.17e-2)" "unprognostic (1.98e-3)" "unprognostic (1.03e-1)" "unprognostic (2.67e-2)" "unprognostic (7.87e-2)" "unprognostic (6.91e-2)" "unprognostic (4.58e-2)" "unprognostic (2.22e-1)" "unprognostic (8.35e-3)" "unprognostic (1.07e-1)" "unprognostic (1.22e-1)" "unprognostic (2.69e-1)" "unprognostic (4.73e-2)" "unprognostic (1.10e-2)" "unprognostic (2.73e-1)" "unprognostic (1.47e-1)" "unprognostic (6.97e-2)" "unprognostic (2.56e-1)" TSPAN31 SAS ENSG00000135452 "Tetraspanin 31" Q12999 12 57738013-57750219 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 187.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030758, HPA057489" Approved Approved "Nucleoplasm,Golgi apparatus,Cytokinetic bridge,Cytosol" Yes No "Cluster 29: Non-specific - Unknown function" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 38: Non-specific - Transcription" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 5 "Golgi apparatus" "Nucleoplasm, Cytokinetic bridge, Cytosol" "HPA030758: , HPA057489: " "unprognostic (6.14e-2)" "potential prognostic unfavorable (4.56e-4)" "unprognostic (1.13e-1)" "potential prognostic unfavorable (7.92e-5)" "unprognostic (1.22e-1)" "unprognostic (1.34e-1)" "unprognostic (3.39e-2)" "unprognostic (1.27e-1)" "potential prognostic unfavorable (4.96e-4)" "unprognostic (1.27e-1)" "potential prognostic favorable (3.52e-7)" "unprognostic (7.32e-3)" "unprognostic (2.19e-1)" "unprognostic (2.56e-1)" "unprognostic (2.34e-1)" "unprognostic (1.71e-1)" "unprognostic (3.31e-1)" "unprognostic (1.29e-1)" "unprognostic (3.93e-2)" "unprognostic (2.06e-1)" "unprognostic (2.83e-3)" "unprognostic (2.60e-1)" "unprognostic (1.11e-1)" "unprognostic (2.81e-1)" "unprognostic (8.68e-2)" "unprognostic (7.42e-2)" "unprognostic (2.16e-2)" "unprognostic (1.49e-1)" "unprognostic (7.38e-2)" "unprognostic (3.47e-2)" "unprognostic (4.94e-3)" TSPAN32 "PHEMX, TSSC6" ENSG00000064201 "Tetraspanin 32" Q96QS1 11 2301997-2318204 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 18.8;heart muscle: 10.7;lymphoid tissue: 5.2" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 36.9;cDC: 37.6;Hematopoietic stem cells: 58.7;Innate lymphoid cells: 37.0;Mast cells: 27.7;Megakaryocyte progenitors: 85.4;Megakaryocyte-Erythroid progenitors: 59.3;Megakaryocytes: 43.3;Neutrophil progenitors: 24.1;NK-cells: 54.8;Platelets: 115.6;T-cells: 25.7" "Cell type enriched" "Detected in some" 12 "leukocyte: 51.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in some" 6 "Leukemia: 9.0" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Heart muscle - Cardiomyocytes, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA024135 Uncertain Approved Nucleoplasm NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 15: Bone marrow - Innate immune response" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" Nucleoplasm "HPA024135: " "unprognostic (2.98e-2)" "unprognostic (1.90e-1)" "unprognostic (1.53e-3)" "unprognostic (1.55e-2)" "unprognostic (1.06e-1)" TSPAN33 "MGC50844, Penumbra" ENSG00000158457 "Tetraspanin 33" Q86UF1 7 129144707-129169699 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 46.7" "Cell type enriched" "Detected in many" 6 "Platelets: 987.6" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Kidney Renal Papillary Cell Carcinoma (TCGA): 45.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.1;naive B-cell: 1.3" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in all" "lymphoma: 34.0" "Minor Salivary Gland - Minor salivary glandular cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020357 Enhanced Approved Microtubules NA NA 9100 "Cluster 2: Dendritic cells - Unknown function" "Cluster 72: Kidney - Transmembrane transport" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 55: Lymphoma - Immune response" "Cluster 47: Platelets - Hemostasis" 47 Microtubules "HPA020357: " "unprognostic (1.08e-1)" "unprognostic (9.84e-2)" "unprognostic (1.87e-1)" "unprognostic (2.21e-2)" "unprognostic (2.69e-1)" "unprognostic (1.15e-1)" "unprognostic (1.06e-1)" "unprognostic (1.94e-1)" "unprognostic (2.60e-1)" "unprognostic (2.14e-1)" "potential prognostic favorable (9.32e-5)" "unprognostic (3.94e-1)" "unprognostic (2.08e-1)" "unprognostic (9.26e-2)" "potential prognostic unfavorable (7.36e-4)" "unprognostic (1.63e-1)" "unprognostic (2.16e-1)" "unprognostic (2.10e-1)" "unprognostic (2.77e-1)" "unprognostic (4.83e-1)" "unprognostic (1.92e-1)" "unprognostic (1.63e-3)" "unprognostic (3.47e-2)" "unprognostic (2.98e-1)" "unprognostic (5.27e-2)" "unprognostic (8.63e-2)" "unprognostic (7.29e-2)" "unprognostic (6.31e-2)" "unprognostic (1.43e-1)" "unprognostic (6.28e-3)" "unprognostic (2.07e-1)" TSPAN4 "NAG-2, TETRASPAN, TM4SF7, TSPAN-4" ENSG00000214063 "Tetraspanin 4" O14817 11 842812-867116 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 155.7;Decidual stromal cells: 267.7;Fibroblasts: 143.1;Hofbauer cells: 365.7;Kupffer cells: 173.2;Leydig cells: 129.3;Lymphatic endothelial cells: 147.9;Melanocytes: 175.1" "Group enriched" "Detected in many" 4 "choroid plexus epithelial cell: 32.0;endothelial cell: 51.8;fibroblast: 61.5;pericyte: 74.1;vascular associated smooth muscle cell: 29.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "classical monocyte: 146.7;intermediate monocyte: 143.7;myeloid DC: 101.4;NK-cell: 95.8;non-classical monocyte: 40.2" "Group enriched" "Detected in all" 10 "dendritic cells: 101.4;monocytes: 146.7;NK-cells: 95.8" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Skin - Fibroblasts_2" "Region enriched" "Detected in all" 4 "cerebellum: 142.8" "Low region specificity" "Detected in all" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 13: Lung - Secretion" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 24: Non-specific - Unknown function" "Cluster 108: Fibroblasts - ECM organization" 30 "unprognostic (1.35e-1)" "unprognostic (4.72e-2)" "unprognostic (3.49e-2)" "unprognostic (7.38e-2)" "unprognostic (5.72e-2)" "unprognostic (3.78e-2)" "validated prognostic unfavorable (1.40e-5)" "validated prognostic unfavorable (9.37e-4)" "unprognostic (3.43e-2)" "unprognostic (4.67e-3)" "potential prognostic favorable (8.98e-4)" "unprognostic (3.37e-1)" "unprognostic (1.75e-1)" "potential prognostic unfavorable (5.65e-6)" "unprognostic (9.83e-2)" "unprognostic (1.71e-1)" "unprognostic (2.36e-1)" "unprognostic (1.64e-2)" "unprognostic (2.06e-1)" "unprognostic (5.85e-2)" "unprognostic (1.81e-1)" "unprognostic (1.49e-1)" "unprognostic (6.44e-2)" "unprognostic (2.22e-1)" "unprognostic (1.52e-1)" "unprognostic (8.13e-3)" "unprognostic (1.74e-1)" "unprognostic (2.45e-2)" "unprognostic (7.61e-2)" "unprognostic (5.10e-2)" "unprognostic (2.74e-1)" TSPAN5 "NET-4, TM4SF9, Tspan-5" ENSG00000168785 "Tetraspanin 5" P62079 4 98470367-98658611 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 67.3" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 478.7;Gonadotrophs: 426.0;Lymphatic endothelial cells: 621.1;Oligodendrocytes: 572.6" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 65.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 37 "B-cells: 3.0;NK-cells: 3.9;T-cells: 6.1" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Prostate - Smooth muscle cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA079522 Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 27: Cerebellum - Synaptic function" "Cluster 34: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 3 "Nucleoplasm, Plasma membrane" "HPA079522: " "unprognostic (4.09e-3)" "unprognostic (6.08e-2)" "unprognostic (1.70e-1)" "unprognostic (8.33e-2)" "unprognostic (7.79e-2)" "unprognostic (8.84e-2)" "unprognostic (2.80e-1)" "unprognostic (6.22e-2)" "unprognostic (1.24e-2)" "unprognostic (4.48e-2)" "validated prognostic favorable (8.91e-4)" "validated prognostic favorable (6.66e-4)" "potential prognostic unfavorable (2.53e-4)" "unprognostic (1.68e-2)" "unprognostic (2.92e-2)" "unprognostic (4.82e-3)" "potential prognostic unfavorable (3.80e-4)" "unprognostic (8.18e-2)" "unprognostic (6.27e-3)" "unprognostic (6.14e-2)" "unprognostic (2.80e-1)" "unprognostic (1.49e-2)" "unprognostic (3.03e-2)" "unprognostic (2.03e-1)" "unprognostic (1.25e-1)" "unprognostic (1.34e-1)" "unprognostic (1.48e-1)" "unprognostic (3.02e-3)" "unprognostic (9.97e-2)" "unprognostic (4.66e-3)" "unprognostic (3.08e-1)" TSPAN6 "T245, TM4SF6, TSPAN-6" ENSG00000000003 "Tetraspanin 6" O43657 X 100627108-100639991 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Esophageal apical cells: 1280.5;Late spermatids: 3513.3" "Cell type enhanced" "Detected in many" "astrocyte: 32.6;ependymal cell: 58.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 2.1" "Lineage enriched" "Detected in single" 7 "T-cells: 2.1" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Kidney - Fibroblasts, Liver - Hepatocytes, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004109 Approved Approved "Nucleoli fibrillar center,Cell Junctions,Cytosol" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 2 "Cell Junctions, Cytosol" "Nucleoli fibrillar center" "HPA004109: " "unprognostic (1.78e-1)" "unprognostic (1.74e-1)" "unprognostic (2.68e-1)" "unprognostic (4.04e-1)" "unprognostic (4.71e-2)" "unprognostic (6.70e-3)" "unprognostic (3.91e-2)" "unprognostic (1.08e-1)" "potential prognostic unfavorable (3.06e-4)" "unprognostic (6.78e-2)" "potential prognostic favorable (5.30e-6)" "unprognostic (1.79e-2)" "unprognostic (9.46e-3)" "unprognostic (1.41e-1)" "unprognostic (2.82e-2)" "unprognostic (7.08e-2)" "unprognostic (6.58e-3)" "unprognostic (2.60e-2)" "unprognostic (1.14e-1)" "unprognostic (5.66e-2)" "unprognostic (5.14e-1)" "potential prognostic unfavorable (1.14e-4)" "unprognostic (1.26e-2)" "unprognostic (4.08e-2)" "unprognostic (7.25e-3)" "unprognostic (2.15e-2)" "unprognostic (2.03e-2)" "unprognostic (9.82e-2)" "unprognostic (1.64e-1)" "unprognostic (7.15e-2)" "unprognostic (2.41e-1)" TSPAN7 "A15, CD231, DXS1692E, MRX58, MXS1, TALLA-1, TM4SF2" ENSG00000156298 "Tetraspanin 7" P41732 X 38561542-38688920 "CD markers, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Host-virus interaction" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 677.1" "Cell type enhanced" "Detected in many" "Astrocytes: 252.4;Bergmann glia: 196.8;Brain excitatory neurons: 283.8;Brain inhibitory neurons: 320.3;Myonuclei: 222.1;Oligodendrocyte progenitor cells: 432.9;Other brain neurons: 205.2;Retinal amacrine cells: 154.1;Thymic myoid cells: 199.9;Vascular endothelial cells: 249.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 288.7;Kidney Chromophobe (TCGA): 219.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 60.4;Neuroblastoma: 61.5" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Adrenal gland - Adrenal cortex cells, Breast - Endothelial cells, Colon - Endothelial cells, Liver - Sinusoid Endothelial cells, Minor Salivary Gland - Endothelial cells, Prostate - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003140, CAB062566, CAB068245" Enhanced NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 5 "CAB062566: , CAB068245: , HPA003140: " "unprognostic (1.96e-2)" "unprognostic (2.44e-2)" "unprognostic (5.30e-2)" "unprognostic (3.65e-1)" "unprognostic (2.67e-1)" "unprognostic (1.32e-1)" "unprognostic (2.94e-1)" "unprognostic (3.42e-3)" "unprognostic (1.98e-3)" "unprognostic (1.49e-1)" "validated prognostic favorable (2.08e-11)" "validated prognostic favorable (3.98e-6)" "unprognostic (6.50e-3)" "unprognostic (2.12e-3)" "unprognostic (1.92e-3)" "unprognostic (2.05e-3)" "unprognostic (2.66e-2)" "unprognostic (8.54e-2)" "unprognostic (2.21e-1)" "unprognostic (3.72e-2)" "unprognostic (1.81e-1)" "potential prognostic favorable (2.70e-4)" "unprognostic (7.93e-2)" "unprognostic (7.47e-2)" "unprognostic (2.56e-1)" "unprognostic (4.94e-2)" "unprognostic (2.19e-2)" "unprognostic (2.70e-3)" "unprognostic (1.09e-1)" "unprognostic (1.75e-1)" "unprognostic (6.32e-2)" TSPAN8 "CO-029, TM4SF3" ENSG00000127324 "Tetraspanin 8" P19075 12 71125085-71441898 "Cancer-related genes, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 891.6;stomach 1: 595.5" "Cell type enhanced" "Detected in many" "Colonocytes: 2747.0;Enteric stem cells: 2165.8;Enteric transient amplifying cells: 1562.0;Enterocytes: 3175.4;Foveolar cells: 999.0;Gastric chief cells: 997.0;Gastric progenitor cells: 1532.9;Goblet cells: 666.7;Mucous neck cells: 739.0;Paneth cells: 1492.8;Parietal cells: 1387.8" "Group enriched" "Detected in many" 5 "oligodendrocyte: 33.2;pericyte: 14.6;vascular associated smooth muscle cell: 19.3" "Group enriched" "Detected in many" 4 "Colon Adenocarcinoma (TCGA): 984.1;Pancreatic Adenocarcinoma (TCGA): 542.0;Rectum Adenocarcinoma (TCGA): 870.2;Stomach Adenocarcinoma (TCGA): 633.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 618.1;Gastric cancer: 461.0" "Colon - Colon enterocytes, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA022273, CAB026009, HPA044337" Enhanced Approved Vesicles NA NA "Cluster 77: Intestine - Digestion" "Cluster 30: White matter - Myelination" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 42 Vesicles "CAB026009: , HPA022273: , HPA044337: " "unprognostic (6.64e-1)" "unprognostic (6.43e-2)" "unprognostic (2.05e-2)" "unprognostic (3.21e-2)" "unprognostic (4.15e-2)" "unprognostic (1.04e-1)" "unprognostic (1.12e-1)" "unprognostic (7.99e-3)" "unprognostic (7.13e-3)" "unprognostic (5.28e-2)" "unprognostic (2.72e-2)" "unprognostic (9.52e-3)" "unprognostic (1.78e-1)" "unprognostic (1.18e-2)" "unprognostic (1.09e-1)" "unprognostic (8.55e-2)" "unprognostic (1.40e-1)" "unprognostic (2.41e-1)" "unprognostic (7.44e-2)" "unprognostic (1.95e-2)" "unprognostic (2.48e-3)" "potential prognostic favorable (5.34e-4)" "unprognostic (3.28e-1)" "unprognostic (8.53e-2)" "unprognostic (8.59e-3)" "unprognostic (1.74e-2)" "unprognostic (1.75e-1)" "unprognostic (3.71e-1)" TSPAN9 NET-5 ENSG00000011105 "Tetraspanin 9" O75954 12 3077355-3286564 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 148.5;heart muscle: 120.6" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 377.4;Platelets: 284.6;Proximal tubule cells: 342.0;Renal collecting duct intercalated cells: 287.3;Renal connecting tubule cells: 276.2;Retinal bipolar cells: 391.2;Retinal ganglion cells: 235.6" "Cell type enhanced" "Detected in all" "endothelial cell: 254.8;upper rhombic lip: 227.3" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebellum: 198.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Heart muscle - Cardiomyocytes, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebellum: 80.5" HPA014002 Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 65000 "Cluster 64: Non-specific - Transcription" "Cluster 35: Non-specific - DNA binding" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 1 "Nucleoplasm, Golgi apparatus" Cytosol "HPA014002: " "unprognostic (7.23e-2)" "unprognostic (7.56e-2)" "unprognostic (1.94e-1)" "unprognostic (1.76e-2)" "unprognostic (8.64e-2)" "unprognostic (3.12e-2)" "unprognostic (3.13e-2)" "unprognostic (6.63e-3)" "unprognostic (2.37e-2)" "unprognostic (4.82e-2)" "potential prognostic favorable (7.48e-6)" "unprognostic (4.18e-3)" "unprognostic (1.41e-1)" "unprognostic (1.03e-1)" "unprognostic (1.22e-1)" "unprognostic (1.73e-1)" "unprognostic (1.72e-1)" "unprognostic (1.56e-1)" "unprognostic (4.72e-2)" "unprognostic (7.22e-3)" "unprognostic (8.92e-2)" "unprognostic (8.21e-3)" "unprognostic (1.02e-1)" "unprognostic (2.38e-2)" "unprognostic (5.70e-2)" "unprognostic (7.96e-3)" "potential prognostic unfavorable (2.36e-4)" "unprognostic (5.41e-2)" "unprognostic (1.76e-1)" "unprognostic (8.28e-2)" "unprognostic (8.38e-2)" TSPEAR "C21orf29, DFNB98, MGC11251, TSP-EAR" ENSG00000175894 "Thrombospondin type laminin G domain and EAR repeats" Q8WU66 21 44497893-44711572 "Disease related genes, Human disease related genes, Predicted secreted proteins" Hearing "Deafness, Disease variant, Ectodermal dysplasia, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 1.7;pituitary gland: 2.3;testis: 2.4" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 30.2;Corticotrophs: 105.1;Early spermatids: 51.1;Gonadotrophs: 40.7;Lactotrophs: 19.4;Lymphatic endothelial cells: 53.7;Podocytes: 68.4;Somatotrophs: 24.4;Thyrotrophs: 119.8" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 14.0;eccentric medium spiny neuron: 9.7;medium spiny neuron: 14.1" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 2.8" "Pituitary gland - Thyrotropes, Stomach - Gastric enteroendocrine cells, Testis - Early spermatids" "Not detected" "Not detected" "Region enhanced" "Detected in single" "olfactory bulb: 1.3" "CAB034203, CAB034204, HPA052995" Uncertain "Secreted in other tissues" Other NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "CAB034203: , CAB034204: , HPA052995: " TSPO "BZRP, DBI, IBP, MBR, mDRC, PBR, pk18, PKBS, TSPO1" ENSG00000100300 "Translocator protein" P30536 22 43151547-43163242 "Cancer-related genes, FDA approved drug targets, Predicted membrane proteins" "Lipid transport, Transport" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 704.4" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 4707.1;Esophageal basal cells: 1663.5;Esophageal suprabasal cells: 3416.7;Neutrophil progenitors: 1082.3;Neutrophils: 1551.8;Suprabasal keratinocytes: 1288.6" "Cell type enhanced" "Detected in many" "leukocyte: 74.0;vascular associated smooth muscle cell: 64.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipocytes (Visceral), Liver - Vascular endothelial cells, Lung - Macrophages, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011232, HPA046260, HPA072304" Uncertain Supported Vesicles,Mitochondria,Cytosol NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 66: Non-specific - Mitochondria" "Cluster 85: Squamous epithelial cells - Keratinization" 18 Mitochondria "Vesicles, Cytosol" "CAB011232: , HPA046260: , HPA072304: " "unprognostic (1.76e-1)" "unprognostic (7.80e-2)" "unprognostic (2.07e-2)" "unprognostic (1.71e-1)" "unprognostic (5.26e-2)" "unprognostic (4.34e-2)" "unprognostic (2.56e-1)" "unprognostic (4.50e-2)" "unprognostic (3.36e-2)" "unprognostic (6.89e-2)" "unprognostic (2.46e-3)" "unprognostic (6.77e-3)" "unprognostic (1.58e-2)" "potential prognostic unfavorable (1.36e-5)" "unprognostic (4.74e-3)" "unprognostic (2.11e-1)" "unprognostic (1.00e-1)" "unprognostic (1.49e-1)" "unprognostic (2.62e-1)" "unprognostic (5.65e-2)" "unprognostic (3.22e-2)" "unprognostic (1.87e-3)" "unprognostic (1.46e-1)" "unprognostic (1.41e-1)" "unprognostic (1.74e-1)" "unprognostic (2.61e-1)" "unprognostic (2.77e-1)" "unprognostic (6.10e-3)" "unprognostic (1.78e-1)" "unprognostic (1.78e-1)" "unprognostic (5.67e-2)" TSPO2 "BZRPL1, dJ34B21.2" ENSG00000112212 "Translocator protein 2" Q5TGU0 6 41042467-41044337 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 39 "bone marrow: 47.3" "Group enriched" "Detected in some" 23 "Erythrocyte progenitors: 31.6;Erythrocytes: 61.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Liver Hepatocellular Carcinoma (TCGA): 1.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 2.0" "Spleen - Erythrocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA060691, HPA066996" Enhanced "Plasma membrane" NA NA "Cluster 15: Bone marrow - Innate immune response" "Cluster 6: Non-specific - Immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 49 "Plasma membrane" "HPA060691: , HPA066996: " "unprognostic (1.42e-1)" "unprognostic (2.85e-3)" "unprognostic (1.06e-1)" "unprognostic (7.66e-2)" "unprognostic (8.59e-3)" TSPOAP1 "BZRAP1, KIAA0612, PRAX-1, RIM-BP1, RIMBP1" ENSG00000005379 "TSPO associated protein 1" O95153 17 58301228-58328795 "Plasma proteins, Predicted intracellular proteins, Transporters" "Disease variant, Dystonia, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 149.3" "Cell type enhanced" "Detected in many" "Astrocytes: 90.1;Retinal ganglion cells: 85.0;Retinal horizontal cells: 152.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.7" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in many" 5 "Leukemia: 52.6" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024662, HPA025244" Enhanced NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 109: Neurons - Neuronal signaling" 5 "HPA024662: , HPA025244: " "unprognostic (1.41e-3)" "unprognostic (1.31e-1)" "unprognostic (4.74e-2)" "unprognostic (1.96e-2)" "unprognostic (1.59e-1)" "unprognostic (1.83e-1)" "unprognostic (7.88e-2)" "unprognostic (4.74e-3)" "unprognostic (5.60e-2)" "unprognostic (3.28e-2)" "potential prognostic favorable (8.68e-4)" "unprognostic (1.26e-3)" "unprognostic (8.70e-2)" "potential prognostic favorable (7.47e-5)" "unprognostic (3.04e-1)" "unprognostic (2.43e-1)" "unprognostic (3.54e-2)" "unprognostic (1.54e-1)" "unprognostic (9.82e-3)" "potential prognostic favorable (1.49e-6)" "unprognostic (8.52e-2)" "unprognostic (2.31e-1)" "unprognostic (1.61e-1)" "unprognostic (6.28e-2)" "unprognostic (4.32e-2)" "unprognostic (1.02e-1)" "unprognostic (1.19e-1)" "unprognostic (6.75e-2)" "unprognostic (2.22e-1)" TSPY1 "CT78, TSPY" ENSG00000258992 "Testis specific protein Y-linked 1" Q01534 Y 9466955-9469749 "Disease related genes, Predicted intracellular proteins" "Differentiation, Gonadal differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 72 "testis: 7.1" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Testicular Germ Cell Tumor (TCGA): 15.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 23 "Myeloma: 18.8" "HPA049384, HPA067289" Supported Approved Cytosol NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 20: Myeloma - Immune response" 1 Cytosol "HPA049384: , HPA067289: " "unprognostic (2.14e-1)" TSPY10 ENSG00000236424 "Testis specific protein Y-linked 10" P0CW01 Y 9527880-9530682 "Predicted intracellular proteins" "Differentiation, Gonadal differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 13 "testis: 1.8" "Group enriched" "Detected in some" 11 "Differentiating spermatogonia: 12.8;Early primary spermatocytes: 3.8;Undifferentiated spermatogonia: 7.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Testicular Germ Cell Tumor (TCGA): 1.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 8 "Myeloma: 5.7" "HPA049384, HPA067289" Supported Approved Cytosol NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 20: Myeloma - Immune response" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 2 Cytosol "HPA049384: , HPA067289: " "unprognostic (3.14e-2)" TSPY2 TSPYQ1 ENSG00000168757 "Testis specific protein Y-linked 2" A6NKD2 Y 6246223-6249019 "Predicted intracellular proteins" "Differentiation, Gonadal differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 72 "testis: 7.2" "Group enriched" "Detected in some" 27 "Differentiating spermatogonia: 27.3;Early primary spermatocytes: 14.1;Undifferentiated spermatogonia: 19.6" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Testicular Germ Cell Tumor (TCGA): 11.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 8 "Myeloma: 8.5" "HPA049384, HPA067289" Supported Approved Cytosol NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 20: Myeloma - Immune response" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 1 Cytosol "HPA049384: , HPA067289: " "unprognostic (4.61e-1)" TSPY3 CT78 ENSG00000228927 "Testis specific protein Y-linked 3" P0CV98 Y 9398421-9401223 "Predicted intracellular proteins" "Differentiation, Gonadal differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 5 "testis: 2.8" "Group enriched" "Detected in some" 9 "Differentiating spermatogonia: 6.6;Early primary spermatocytes: 2.9;Undifferentiated spermatogonia: 2.1" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "Testicular Germ Cell Tumor (TCGA): 6.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 15 "Myeloma: 13.3" "HPA049384, HPA067289" Supported Approved Cytosol NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 20: Myeloma - Immune response" "Cluster 106: Spermatogonia - Spermatogonial differentiation" Cytosol "HPA049384: , HPA067289: " "unprognostic (2.89e-1)" TSPY4 ENSG00000233803 "Testis specific protein Y-linked 4" P0CV99 Y 9337464-9340284 "Predicted intracellular proteins" "Differentiation, Gonadal differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 149 "testis: 31.4" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "Testicular Germ Cell Tumor (TCGA): 86.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 38 "Myeloma: 153.6" "HPA049384, HPA067289" Supported Approved Cytosol NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 20: Myeloma - Immune response" Cytosol "HPA049384: , HPA067289: " "unprognostic (2.14e-1)" TSPY8 ENSG00000229549 "Testis specific protein Y-linked 8" P0CW00 Y 9357797-9360599 "Predicted intracellular proteins" "Differentiation, Gonadal differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 13 "testis: 1.3" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 6.0;Early primary spermatocytes: 3.4;Undifferentiated spermatogonia: 1.2" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 26 "Testicular Germ Cell Tumor (TCGA): 2.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 87 "Myeloma: 9.2" "HPA049384, HPA067289" Supported Approved Cytosol NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 20: Myeloma - Immune response" "Cluster 106: Spermatogonia - Spermatogonial differentiation" Cytosol "HPA049384: , HPA067289: " "unprognostic (7.51e-1)" TSPY9 TSPY9P ENSG00000238074 "Testis specific protein Y-linked 9" A0A494C1R9 Y 9487267-9490081 "Predicted intracellular proteins" "Differentiation, Gonadal differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Tissue enriched" "Detected in single" 51 "testis: 14.0" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "Testicular Germ Cell Tumor (TCGA): 18.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 29 "Myeloma: 74.0" "HPA049384, HPA067289" Supported Approved Cytosol NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 20: Myeloma - Immune response" Cytosol "HPA049384: , HPA067289: " "unprognostic (5.56e-1)" TSPYL1 TSPYL ENSG00000189241 "TSPY like 1" Q9H0U9 6 116267760-116279930 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Parietal cells: 305.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031970 Supported Supported Nucleoplasm,Nucleoli No No "Cluster 32: Basophils - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 97: Non-specific - Cellular respiration" 37 "Nucleoplasm, Nucleoli" "HPA031970: " "unprognostic (1.41e-2)" "unprognostic (6.41e-3)" "unprognostic (3.03e-2)" "unprognostic (2.36e-2)" "unprognostic (1.42e-2)" "unprognostic (8.07e-2)" "unprognostic (1.99e-1)" "unprognostic (3.29e-3)" "unprognostic (2.59e-2)" "unprognostic (5.63e-2)" "validated prognostic favorable (9.45e-11)" "validated prognostic favorable (8.23e-6)" "unprognostic (7.44e-3)" "unprognostic (3.06e-1)" "unprognostic (7.42e-2)" "unprognostic (1.77e-2)" "unprognostic (6.79e-2)" "unprognostic (9.05e-2)" "unprognostic (2.58e-2)" "unprognostic (9.51e-3)" "unprognostic (1.27e-1)" "unprognostic (6.12e-3)" "unprognostic (8.93e-2)" "unprognostic (1.26e-1)" "unprognostic (3.52e-1)" "unprognostic (3.33e-2)" "unprognostic (3.56e-1)" "unprognostic (5.90e-2)" "unprognostic (3.85e-1)" "unprognostic (2.58e-1)" "unprognostic (2.67e-2)" TSPYL2 "CDA1, CINAP, CTCL, DENTT, HRIHFB2216, SE20-4, TSPX" ENSG00000184205 "TSPY like 2" Q9H2G4 X 53082367-53088540 "Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Innate lymphoid cells: 230.1;Mast cells: 224.9;Ovarian stromal cells: 345.6;pDCs: 241.7;T-cells: 325.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044133 Approved NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 64: Non-specific - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 20: Non-specific - Transcription regulation" 54 "HPA044133: " "potential prognostic favorable (2.64e-5)" "unprognostic (4.16e-2)" "unprognostic (5.41e-2)" "unprognostic (1.42e-1)" "unprognostic (3.47e-2)" "unprognostic (3.65e-2)" "unprognostic (1.09e-1)" "unprognostic (7.13e-2)" "unprognostic (1.50e-1)" "unprognostic (5.75e-3)" "unprognostic (4.21e-2)" "unprognostic (7.65e-2)" "unprognostic (7.25e-3)" "unprognostic (1.26e-1)" "unprognostic (3.24e-1)" "unprognostic (1.94e-3)" "unprognostic (6.55e-2)" "unprognostic (1.73e-2)" "unprognostic (2.17e-2)" "unprognostic (6.02e-3)" "unprognostic (2.04e-2)" "potential prognostic favorable (3.56e-8)" "unprognostic (9.27e-3)" "unprognostic (4.22e-1)" "unprognostic (1.95e-1)" "unprognostic (7.57e-3)" "unprognostic (2.28e-2)" "unprognostic (4.01e-2)" "unprognostic (4.85e-1)" "unprognostic (3.21e-1)" "unprognostic (6.80e-2)" TSPYL4 "dJ486I3.2, KIAA0721" ENSG00000187189 "TSPY like 4" Q9UJ04 6 116249964-116254075 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 88.5" "Cell type enhanced" "Detected in many" "Parietal cells: 58.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044863 Approved NA Yes "Cluster 24: Non-specific - Transcription" "Cluster 27: Cerebellum - Synaptic function" "Cluster 1: Neurons - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 98: Neurons - Neurotransmission & signaling" 15 "HPA044863: " "unprognostic (2.81e-3)" "unprognostic (3.41e-2)" "potential prognostic unfavorable (4.38e-4)" "unprognostic (1.24e-1)" "unprognostic (8.65e-2)" "unprognostic (1.84e-2)" "unprognostic (1.04e-1)" "unprognostic (2.02e-2)" "unprognostic (1.10e-1)" "unprognostic (1.38e-1)" "potential prognostic favorable (8.00e-8)" "unprognostic (3.34e-3)" "unprognostic (3.75e-3)" "unprognostic (7.94e-2)" "unprognostic (8.00e-2)" "unprognostic (6.21e-3)" "unprognostic (2.23e-1)" "unprognostic (6.12e-2)" "unprognostic (8.52e-2)" "unprognostic (1.37e-2)" "unprognostic (1.19e-1)" "unprognostic (3.34e-3)" "unprognostic (1.68e-1)" "unprognostic (2.72e-1)" "unprognostic (2.35e-2)" "unprognostic (6.19e-2)" "unprognostic (4.10e-1)" "unprognostic (1.24e-2)" "unprognostic (1.99e-1)" "unprognostic (2.29e-1)" "unprognostic (5.62e-2)" TSPYL5 KIAA1750 ENSG00000180543 "TSPY like 5" Q86VY4 8 97273488-97277928 "Predicted intracellular proteins" "Growth regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 41.8" "Group enriched" "Detected in many" 8 "Early spermatids: 212.4;Late spermatids: 783.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 32.4" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031347 Enhanced Approved "Golgi apparatus,Cytosol" No No 8800 "Cluster 21: Testis - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 7 Cytosol "Golgi apparatus" "HPA031347: " "unprognostic (4.88e-2)" "unprognostic (2.07e-3)" "unprognostic (5.85e-2)" "unprognostic (6.41e-2)" "unprognostic (3.02e-2)" "unprognostic (1.26e-1)" "unprognostic (1.77e-1)" "unprognostic (2.17e-1)" "unprognostic (1.82e-1)" "potential prognostic favorable (7.30e-5)" "potential prognostic favorable (6.02e-4)" "unprognostic (5.82e-2)" "unprognostic (2.52e-1)" "unprognostic (2.48e-1)" "unprognostic (2.22e-1)" "unprognostic (6.67e-2)" "unprognostic (2.21e-3)" "unprognostic (1.24e-1)" "unprognostic (3.10e-1)" "unprognostic (1.89e-2)" "unprognostic (3.84e-2)" "unprognostic (1.97e-1)" "unprognostic (3.66e-2)" "unprognostic (1.61e-2)" "unprognostic (2.15e-1)" "unprognostic (2.34e-2)" "unprognostic (1.72e-2)" "unprognostic (1.39e-1)" "unprognostic (1.65e-1)" TSPYL6 ENSG00000178021 "TSPY like 6" Q8N831 2 54253178-54256229 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 123 "testis: 20.1" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 11.7;Differentiating spermatogonia: 21.0;Early primary spermatocytes: 29.1;Epicardial cells: 6.8;Late primary spermatocytes: 19.3;Oocytes: 4.6;Retinal ganglion cells: 3.9;Undifferentiated spermatogonia: 20.3" "Cell type enhanced" "Detected in single" "Bergmann glia: 1.4" "Cancer enriched" "Detected in single" 26 "Testicular Germ Cell Tumor (TCGA): 2.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Spermatocytes, Testis - Spermatogonia" "HPA034699, HPA034700" Enhanced Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 9: Non-specific - Receptor signaling" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 13 Nucleoplasm "Nucleoli, Cytosol" "HPA034699: , HPA034700: " "unprognostic (6.36e-2)" TSR1 FLJ10534 ENSG00000167721 "TSR1 ribosome maturation factor" Q2NL82 17 2322396-2336657 "Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 116.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024434, HPA053087" Approved Approved Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Ribosome" "Cluster 42: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 170 Nucleoplasm "HPA024434: , HPA053087: " "unprognostic (5.20e-2)" "unprognostic (3.16e-3)" "unprognostic (5.90e-2)" "unprognostic (1.85e-2)" "unprognostic (1.48e-1)" "unprognostic (9.24e-2)" "unprognostic (7.41e-2)" "unprognostic (2.41e-1)" "unprognostic (2.51e-1)" "potential prognostic unfavorable (5.95e-4)" "unprognostic (3.34e-3)" "unprognostic (4.16e-2)" "unprognostic (1.06e-1)" "unprognostic (3.98e-3)" "unprognostic (2.25e-1)" "unprognostic (1.93e-3)" "unprognostic (7.18e-3)" "unprognostic (5.51e-2)" "unprognostic (1.30e-1)" "unprognostic (2.77e-1)" "unprognostic (1.92e-1)" "unprognostic (3.37e-2)" "unprognostic (2.04e-1)" "unprognostic (1.53e-3)" "unprognostic (1.05e-1)" "unprognostic (1.86e-1)" "unprognostic (1.08e-1)" "unprognostic (1.35e-1)" "unprognostic (8.40e-2)" "unprognostic (4.12e-2)" "unprognostic (2.63e-2)" TSR2 "DT1P1A10, RP1-112K5.2, WGG1" ENSG00000158526 "TSR2 ribosome maturation factor" Q969E8 X 54440404-54448032 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "rRNA processing" "Diamond-Blackfan anemia, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 118.9;Oocytes: 152.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030514 Approved Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 97: Non-specific - Cellular respiration" 24 "Nucleoplasm, Nucleoli" Cytosol "HPA030514: " "unprognostic (3.88e-2)" "unprognostic (2.32e-2)" "unprognostic (5.19e-3)" "unprognostic (8.34e-2)" "unprognostic (8.25e-2)" "unprognostic (1.00e-1)" "unprognostic (1.59e-1)" "unprognostic (1.87e-1)" "unprognostic (2.48e-2)" "unprognostic (6.14e-2)" "validated prognostic favorable (8.46e-8)" "validated prognostic favorable (5.65e-5)" "unprognostic (9.05e-2)" "potential prognostic unfavorable (4.02e-4)" "unprognostic (4.94e-2)" "unprognostic (8.57e-2)" "unprognostic (8.92e-2)" "unprognostic (8.82e-2)" "unprognostic (1.86e-2)" "unprognostic (5.29e-2)" "unprognostic (3.86e-1)" "unprognostic (5.32e-2)" "unprognostic (1.72e-1)" "unprognostic (4.71e-1)" "unprognostic (1.33e-1)" "unprognostic (7.52e-2)" "unprognostic (4.47e-2)" "unprognostic (1.16e-1)" "unprognostic (3.52e-2)" "unprognostic (2.90e-2)" "unprognostic (7.47e-2)" TSR3 "C16orf42, MGC24381" ENSG00000007520 "TSR3 ribosome maturation factor" Q9UJK0 16 1349240-1351878 "Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040760, HPA046265" Uncertain Approved "Golgi apparatus,Cytosol" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 5 Cytosol "Golgi apparatus" "HPA040760: , HPA046265: " "unprognostic (1.61e-1)" "unprognostic (2.98e-1)" "unprognostic (1.22e-1)" "unprognostic (3.61e-1)" "unprognostic (1.25e-1)" "unprognostic (1.94e-2)" "unprognostic (9.57e-2)" "unprognostic (1.87e-1)" "unprognostic (1.07e-1)" "unprognostic (1.10e-1)" "unprognostic (3.12e-1)" "unprognostic (5.04e-2)" "unprognostic (6.02e-3)" "unprognostic (2.08e-2)" "unprognostic (1.67e-1)" "unprognostic (1.09e-1)" "unprognostic (3.00e-1)" "unprognostic (7.03e-2)" "unprognostic (7.01e-2)" "unprognostic (2.43e-1)" "unprognostic (1.90e-1)" "unprognostic (7.08e-2)" "unprognostic (2.79e-1)" "unprognostic (5.78e-2)" "unprognostic (9.45e-2)" "unprognostic (7.31e-2)" "unprognostic (9.82e-2)" "unprognostic (1.14e-1)" "unprognostic (1.23e-1)" TSSC4 ENSG00000184281 "Tumor suppressing subtransferable candidate 4" Q9Y5U2 11 2400488-2403878 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 210.2;Late spermatids: 294.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041801, HPA058763" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 24: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 33 Nucleoplasm Cytosol "HPA041801: , HPA058763: " "unprognostic (2.80e-1)" "unprognostic (6.09e-2)" "unprognostic (1.80e-2)" "unprognostic (7.86e-2)" "unprognostic (1.68e-1)" "unprognostic (7.32e-2)" "unprognostic (1.20e-2)" "unprognostic (3.04e-1)" "unprognostic (2.63e-2)" "unprognostic (4.60e-2)" "unprognostic (1.22e-1)" "unprognostic (3.36e-1)" "unprognostic (3.80e-2)" "potential prognostic unfavorable (6.34e-4)" "unprognostic (5.36e-2)" "unprognostic (5.86e-2)" "unprognostic (1.21e-1)" "unprognostic (4.94e-1)" "unprognostic (1.35e-1)" "unprognostic (2.76e-1)" "unprognostic (4.09e-1)" "unprognostic (1.63e-2)" "unprognostic (2.94e-1)" "unprognostic (5.38e-2)" "unprognostic (9.68e-2)" "unprognostic (1.85e-1)" "unprognostic (2.52e-1)" "unprognostic (3.20e-1)" "unprognostic (1.46e-1)" "unprognostic (1.11e-2)" "potential prognostic favorable (3.35e-4)" TSSK1B "FKSG81, SPOGA4, STK22D, TSSK1" ENSG00000212122 "Testis specific serine kinase 1B" Q9BXA7 5 113432553-113434989 "Enzymes, Predicted membrane proteins" "Differentiation, Spermatogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 230 "testis: 51.7" "Group enriched" "Detected in some" 5 "Early spermatids: 2.9;Late spermatids: 9.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA027827 Enhanced Approved "Nuclear bodies,Centrosome,Basal body,Perinuclear theca,Principal piece,End piece,Annulus" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 61: BICR 18 - Protein kinases" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 8 "Nuclear bodies, Principal piece" "Centrosome, Basal body, Perinuclear theca, End piece, Annulus" "HPA027827: " TSSK2 "FLJ38613, SPOGA2, STK22B" ENSG00000206203 "Testis specific serine kinase 2" Q96PF2 22 19131308-19132622 "Enzymes, Predicted membrane proteins" "Differentiation, Spermatogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 326 "testis: 181.0" "Group enriched" "Detected in some" 9 "Early spermatids: 1919.8;Late spermatids: 5700.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 8 TSSK3 "SPOGA3, STK22C" ENSG00000162526 "Testis specific serine kinase 3" Q96PN8 1 32351521-32364312 "Enzymes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 12.0;testis: 42.4" "Cell type enriched" "Detected in many" 6 "Late spermatids: 2410.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA037516 Approved "Nucleoplasm,Nucleoli,Nuclear bodies" NA NA "Cluster 47: Testis - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 51 "Nucleoplasm, Nucleoli" "Nuclear bodies" "HPA037516: " "unprognostic (1.44e-1)" "unprognostic (2.10e-1)" "unprognostic (1.75e-1)" "unprognostic (2.87e-3)" "unprognostic (7.45e-2)" "unprognostic (8.46e-2)" "unprognostic (5.76e-2)" "potential prognostic unfavorable (6.31e-4)" "unprognostic (1.59e-2)" "unprognostic (4.45e-1)" "unprognostic (1.59e-2)" "unprognostic (1.98e-2)" "unprognostic (3.48e-3)" "unprognostic (6.71e-2)" "unprognostic (2.65e-2)" "unprognostic (4.74e-3)" "unprognostic (4.51e-3)" "unprognostic (5.48e-2)" "unprognostic (1.39e-1)" "unprognostic (8.80e-2)" "unprognostic (1.06e-1)" "unprognostic (2.83e-1)" "unprognostic (6.40e-2)" "unprognostic (8.21e-2)" TSSK4 "C14orf20, STK22E" ENSG00000139908 "Testis specific serine kinase 4" Q6SA08 14 24205696-24208362 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Spermatogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "testis: 36.3" "Group enriched" "Detected in some" 17 "Early spermatids: 178.7;Late primary spermatocytes: 121.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Macrophages, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA060660, HPA077103" Approved Uncertain "Cell Junctions" NA NA "Cluster 47: Testis - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 56: Non-specific - Sensory perception" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 1 "Cell Junctions" "HPA060660: , HPA077103: " "unprognostic (2.78e-3)" "unprognostic (4.60e-3)" "unprognostic (8.72e-3)" "unprognostic (2.09e-1)" "unprognostic (1.15e-2)" "unprognostic (8.67e-2)" TSSK6 "CT72, FLJ24002, SSTK" ENSG00000178093 "Testis specific serine kinase 6" Q9BXA6 19 19512418-19515548 "Enzymes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 135 "testis: 206.2" "Cell type enriched" "Detected in many" 11 "Late spermatids: 18236.6" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA065281 Uncertain "Nuclear bodies" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 6: Non-specific - Immune response" "Cluster 23: Non-specific - Transcription" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 25 "Nuclear bodies" "HPA065281: " "unprognostic (2.76e-2)" "unprognostic (3.52e-2)" "unprognostic (1.20e-1)" "unprognostic (1.15e-1)" "unprognostic (1.19e-1)" "unprognostic (1.36e-1)" TST RDS ENSG00000128311 "Thiosulfate sulfurtransferase" Q16762 22 37010859-37020183 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 555.5" "Cell type enhanced" "Detected in many" "Breast lactating cells: 190.9;Colonocytes: 527.0;Enteric transient amplifying cells: 209.0;Enterocytes: 254.3;Esophageal apical cells: 404.7;Hepatocytes: 437.0;Platelets: 226.5" "Cell type enhanced" "Detected in many" "astrocyte: 20.1;Bergmann glia: 62.7" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 404.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 25.0" "Group enriched" "Detected in all" 6 "dendritic cells: 25.0;granulocytes: 21.9;monocytes: 17.7" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate basal glandular cells, Skin - Sebaceous gland cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003044, HPA003643, CAB009546" Enhanced Supported Mitochondria NA NA 870000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 19: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 6 Mitochondria "CAB009546: , HPA003044: , HPA003643: " "unprognostic (3.44e-1)" "unprognostic (1.19e-1)" "unprognostic (5.12e-2)" "unprognostic (2.30e-1)" "unprognostic (1.00e-1)" "unprognostic (1.15e-3)" "unprognostic (5.83e-2)" "unprognostic (3.59e-2)" "unprognostic (1.86e-1)" "unprognostic (4.44e-3)" "potential prognostic favorable (7.23e-4)" "unprognostic (3.84e-2)" "potential prognostic favorable (1.90e-4)" "unprognostic (6.27e-2)" "unprognostic (1.01e-2)" "unprognostic (2.23e-1)" "unprognostic (2.02e-1)" "unprognostic (7.19e-2)" "unprognostic (2.61e-3)" "unprognostic (9.67e-2)" "unprognostic (3.86e-2)" "unprognostic (2.97e-2)" "unprognostic (7.33e-2)" "unprognostic (4.95e-2)" "unprognostic (7.98e-2)" "unprognostic (8.68e-2)" "unprognostic (2.35e-1)" "unprognostic (3.39e-2)" "unprognostic (2.02e-1)" "unprognostic (1.93e-1)" "unprognostic (2.56e-3)" TSTD1 KAT ENSG00000215845 "Thiosulfate sulfurtransferase like domain containing 1" Q8NFU3 1 161037631-161038977 "Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 377.9;Epididymal principal cells: 436.8;Esophageal apical cells: 428.8;Fallopian tube ciliated cells: 482.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Breast glandular cells, Prostate - Prostate glandular cells, Thyroid gland - Thyroid glandular cells" "Region enriched" "Detected in some" 4 "olfactory bulb: 6.6" "Low region specificity" "Detected in all" "HPA006518, HPA006655" Approved Approved "Cytosol,Cytoplasmic bodies" NA NA 7400 "Cluster 32: Basophils - Transcription" "Cluster 70: Non-specific - Protein processing" "Cluster 33: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" "Cytosol, Cytoplasmic bodies" "HPA006518: , HPA006655: " "unprognostic (3.44e-2)" "unprognostic (1.95e-1)" "unprognostic (2.53e-1)" "unprognostic (6.57e-2)" "unprognostic (5.78e-2)" "unprognostic (5.93e-2)" "unprognostic (1.52e-2)" "potential prognostic unfavorable (1.88e-4)" "unprognostic (1.24e-1)" "unprognostic (2.68e-1)" "unprognostic (7.72e-2)" "unprognostic (2.37e-1)" "unprognostic (3.94e-2)" "unprognostic (1.56e-1)" "unprognostic (4.30e-2)" "unprognostic (2.07e-2)" "unprognostic (6.62e-2)" "unprognostic (6.35e-2)" "unprognostic (5.14e-2)" "unprognostic (2.37e-1)" "unprognostic (3.46e-1)" "unprognostic (4.13e-2)" "unprognostic (1.64e-1)" "unprognostic (1.87e-1)" "unprognostic (8.70e-2)" "unprognostic (2.20e-2)" "unprognostic (1.45e-1)" "unprognostic (7.62e-3)" "unprognostic (5.76e-2)" "unprognostic (3.59e-3)" "unprognostic (7.59e-2)" TSTD2 "C9orf97, PP4189" ENSG00000136925 "Thiosulfate sulfurtransferase like domain containing 2" Q5T7W7 9 97600080-97633368 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epicardial cells: 250.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022537, HPA024241, HPA064304" Uncertain Approved Nucleoplasm NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 18 Nucleoplasm "HPA022537: , HPA024241: , HPA064304: " "unprognostic (4.36e-3)" "unprognostic (2.45e-2)" "unprognostic (2.47e-1)" "unprognostic (6.56e-2)" "unprognostic (1.07e-1)" "unprognostic (4.39e-2)" "unprognostic (5.13e-2)" "potential prognostic favorable (6.61e-4)" "unprognostic (9.46e-3)" "unprognostic (2.49e-2)" "potential prognostic favorable (4.70e-6)" "unprognostic (1.73e-3)" "unprognostic (2.37e-2)" "unprognostic (2.53e-1)" "unprognostic (3.87e-3)" "unprognostic (9.32e-2)" "unprognostic (1.97e-1)" "unprognostic (2.48e-2)" "unprognostic (1.28e-1)" "unprognostic (3.97e-2)" "unprognostic (1.38e-1)" "unprognostic (6.08e-2)" "unprognostic (9.60e-2)" "unprognostic (1.60e-1)" "unprognostic (6.91e-3)" "unprognostic (1.35e-1)" "unprognostic (1.67e-1)" "unprognostic (2.01e-1)" "unprognostic (1.01e-1)" "unprognostic (6.19e-2)" "unprognostic (1.97e-1)" TSTD3 ENSG00000279170 "Thiosulfate sulfurtransferase like domain containing 3" H0UI37 6 99520976-99589899 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 461.0;Epicardial cells: 311.6;Myonuclei: 246.9;Thyrotrophs: 234.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Skeletal muscle - Fibroblasts" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 25: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "unprognostic (1.23e-2)" "unprognostic (2.00e-2)" "unprognostic (7.26e-3)" "unprognostic (1.91e-2)" "unprognostic (7.87e-3)" "unprognostic (6.90e-2)" "unprognostic (1.75e-2)" "unprognostic (2.33e-2)" "unprognostic (3.51e-2)" "unprognostic (1.81e-1)" "unprognostic (8.48e-3)" "unprognostic (2.33e-1)" "unprognostic (3.95e-2)" "unprognostic (1.32e-1)" "unprognostic (2.53e-1)" "unprognostic (1.47e-2)" "unprognostic (1.07e-1)" "unprognostic (3.81e-1)" "unprognostic (1.68e-1)" "unprognostic (3.89e-2)" "unprognostic (3.80e-1)" "unprognostic (2.66e-1)" "unprognostic (4.05e-1)" "unprognostic (1.96e-2)" TTBK1 KIAA1855 ENSG00000146216 "Tau tubulin kinase 1" Q5TCY1 6 43243481-43288258 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 14.5;pituitary gland: 7.2" "Cell type enhanced" "Detected in some" "Astrocytes: 17.2;Brain excitatory neurons: 20.2;Brain inhibitory neurons: 18.3;Corticotrophs: 21.2;Ependymal cells: 12.6;Gonadotrophs: 18.8;Lactotrophs: 37.1;Oligodendrocyte progenitor cells: 23.1;Oligodendrocytes: 24.3;Other brain neurons: 17.4;Retinal amacrine cells: 24.3;Retinal bipolar cells: 26.2;Retinal ganglion cells: 15.5;Retinal horizontal cells: 42.1;Somatotrophs: 29.3;Thyrotrophs: 29.4" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in some" 5 "Glioblastoma Multiforme (TCGA): 6.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "Neuroblastoma: 9.0" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031735, HPA031736" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 2 Cytosol Nucleoplasm "HPA031735: , HPA031736: " "unprognostic (2.85e-1)" "unprognostic (3.03e-2)" "unprognostic (3.09e-1)" "unprognostic (2.32e-2)" "unprognostic (2.08e-2)" "unprognostic (2.10e-3)" "unprognostic (1.10e-2)" "unprognostic (2.23e-2)" TTBK2 "KIAA0847, SCA11" ENSG00000128881 "Tau tubulin kinase 2" Q6IQ55 15 42738730-42920809 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Kinase, Serine/threonine-protein kinase, Transferase" "Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 28.3" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018113 Approved Supported "Microtubules,Primary cilium,Primary cilium transition zone,Basal body,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 109: Neurons - Neuronal signaling" 9 "Microtubules, Cytosol" "Primary cilium, Primary cilium transition zone, Basal body" "HPA018113: " "unprognostic (7.45e-2)" "unprognostic (1.39e-1)" "unprognostic (4.57e-1)" "unprognostic (6.65e-3)" "unprognostic (1.53e-1)" "potential prognostic unfavorable (7.91e-4)" "unprognostic (1.35e-1)" "unprognostic (4.18e-2)" "unprognostic (2.19e-1)" "potential prognostic unfavorable (2.33e-4)" "unprognostic (5.89e-3)" "unprognostic (2.10e-3)" "unprognostic (6.03e-2)" "unprognostic (2.78e-2)" "unprognostic (1.86e-2)" "unprognostic (8.08e-2)" "unprognostic (1.51e-1)" "unprognostic (2.10e-2)" "unprognostic (4.56e-3)" "unprognostic (1.14e-2)" "unprognostic (5.23e-2)" "unprognostic (1.25e-2)" "unprognostic (1.01e-1)" "unprognostic (1.66e-1)" "unprognostic (2.93e-2)" "unprognostic (1.24e-1)" "unprognostic (1.49e-1)" "unprognostic (1.02e-2)" "unprognostic (6.37e-2)" "unprognostic (9.57e-2)" TTC1 TPR1 ENSG00000113312 "Tetratricopeptide repeat domain 1" Q99614 5 160009113-160065543 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036557, HPA057502" Approved Enhanced Cytosol NA NA 6500 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 24: Neutrophils - Innate immunity signal integration" 38 Cytosol "HPA036557: , HPA057502: " "unprognostic (1.81e-2)" "unprognostic (2.36e-2)" "unprognostic (3.68e-2)" "unprognostic (2.26e-2)" "unprognostic (1.24e-1)" "unprognostic (4.19e-3)" "unprognostic (1.17e-1)" "unprognostic (8.83e-3)" "unprognostic (5.39e-3)" "unprognostic (1.16e-1)" "potential prognostic favorable (5.12e-8)" "unprognostic (6.55e-2)" "unprognostic (3.05e-1)" "potential prognostic unfavorable (1.14e-5)" "unprognostic (4.26e-2)" "unprognostic (1.62e-2)" "unprognostic (3.19e-1)" "unprognostic (5.46e-2)" "unprognostic (6.28e-2)" "unprognostic (1.25e-1)" "unprognostic (9.06e-3)" "unprognostic (1.05e-1)" "unprognostic (1.60e-1)" "unprognostic (9.20e-2)" "unprognostic (5.22e-3)" "unprognostic (4.86e-3)" "unprognostic (2.72e-1)" "unprognostic (7.02e-2)" "unprognostic (1.55e-1)" "unprognostic (3.42e-1)" "unprognostic (2.28e-2)" TTC12 "FLJ13859, FLJ20535, TPARM" ENSG00000149292 "Tetratricopeptide repeat domain 12" Q9H892 11 113314579-113383544 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 48.5" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 115.7;Early spermatids: 158.4;Ependymal cells: 166.0;Late primary spermatocytes: 218.5;Late spermatids: 304.0;Respiratory ciliated cells: 137.8;Thyrotrophs: 123.4" "Cell type enhanced" "Detected in many" "ependymal cell: 170.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA038542, HPA038543, HPA061364" Enhanced Approved "Nuclear membrane,Plasma membrane,Cytosol" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 24: Non-specific - Unknown function" "Cluster 34: Ciliated cells - Cilia assembly & function" Cytosol "Nuclear membrane, Plasma membrane" "HPA038542: , HPA038543: , HPA061364: " "unprognostic (3.02e-2)" "unprognostic (1.82e-2)" "unprognostic (2.22e-1)" "unprognostic (6.12e-3)" "unprognostic (7.19e-3)" "unprognostic (1.10e-1)" "unprognostic (2.13e-2)" "potential prognostic unfavorable (2.55e-5)" "unprognostic (1.72e-2)" "unprognostic (3.81e-2)" "potential prognostic favorable (1.08e-5)" "unprognostic (1.65e-3)" "potential prognostic favorable (3.53e-4)" "unprognostic (9.28e-3)" "unprognostic (1.65e-1)" "unprognostic (1.68e-1)" "unprognostic (2.63e-2)" "unprognostic (2.01e-1)" "unprognostic (2.72e-1)" "unprognostic (3.67e-1)" "unprognostic (2.48e-2)" "unprognostic (1.66e-1)" "unprognostic (1.46e-2)" "unprognostic (3.96e-2)" "potential prognostic favorable (1.16e-5)" "unprognostic (4.84e-2)" "unprognostic (6.65e-2)" "unprognostic (3.81e-2)" "unprognostic (1.88e-1)" "unprognostic (1.06e-1)" "unprognostic (1.20e-2)" TTC13 FLJ22584 ENSG00000143643 "Tetratricopeptide repeat domain 13" Q8NBP0 1 230906243-230978875 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 99.3;Microglia: 103.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018022, HPA051558" Uncertain Approved Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 5: Spleen - Immune response" "Cluster 55: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 4 Nucleoplasm "HPA018022: , HPA051558: " "unprognostic (7.57e-2)" "unprognostic (2.55e-1)" "unprognostic (7.41e-2)" "unprognostic (2.67e-1)" "unprognostic (3.17e-1)" "unprognostic (1.89e-1)" "unprognostic (9.07e-2)" "unprognostic (1.16e-2)" "potential prognostic favorable (7.73e-4)" "unprognostic (1.35e-2)" "unprognostic (5.99e-3)" "unprognostic (1.32e-2)" "unprognostic (1.50e-2)" "unprognostic (3.32e-2)" "unprognostic (1.86e-1)" "unprognostic (1.98e-1)" "unprognostic (2.89e-1)" "unprognostic (5.11e-2)" "unprognostic (5.59e-2)" "unprognostic (1.54e-1)" "unprognostic (3.61e-2)" "potential prognostic favorable (3.41e-4)" "unprognostic (1.27e-1)" "unprognostic (2.78e-1)" "unprognostic (7.10e-2)" "unprognostic (2.45e-2)" "unprognostic (8.37e-2)" "unprognostic (4.33e-2)" "unprognostic (3.11e-1)" "unprognostic (4.50e-3)" "unprognostic (1.88e-1)" TTC14 "FLJ00166, KIAA1980" ENSG00000163728 "Tetratricopeptide repeat domain 14" Q96N46 3 180602163-180617828 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009295 Uncertain Approved Nucleoplasm NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 64: Non-specific - Transcription" "Cluster 9: Non-specific - Receptor signaling" "Cluster 63: Non-specific - Protein processing" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 1 Nucleoplasm "HPA009295: " "unprognostic (1.09e-1)" "unprognostic (1.14e-2)" "unprognostic (1.81e-1)" "unprognostic (2.74e-1)" "unprognostic (1.07e-1)" "unprognostic (3.17e-2)" "unprognostic (8.91e-2)" "unprognostic (1.12e-2)" "unprognostic (1.31e-1)" "unprognostic (5.98e-2)" "unprognostic (1.87e-1)" "unprognostic (1.53e-2)" "unprognostic (1.77e-1)" "unprognostic (4.77e-3)" "unprognostic (8.08e-2)" "unprognostic (1.77e-1)" "unprognostic (1.75e-1)" "unprognostic (3.71e-1)" "unprognostic (1.25e-2)" "unprognostic (2.12e-1)" "unprognostic (1.24e-1)" "unprognostic (1.99e-1)" "potential prognostic unfavorable (8.50e-4)" "unprognostic (2.33e-2)" "potential prognostic favorable (5.58e-4)" "unprognostic (3.73e-2)" "unprognostic (1.10e-3)" "unprognostic (8.00e-2)" "unprognostic (2.64e-1)" "unprognostic (7.05e-2)" "unprognostic (1.45e-1)" TTC16 FLJ32780 ENSG00000167094 "Tetratricopeptide repeat domain 16" Q8NEE8 9 127716079-127731590 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "fallopian tube: 6.5;testis: 15.2" "Group enriched" "Detected in some" 4 "Early spermatids: 117.4;Late spermatids: 427.3" "Group enriched" "Detected in some" 4 "choroid plexus epithelial cell: 3.9;ependymal cell: 13.4;leukocyte: 10.2;oligodendrocyte precursor cell: 6.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "gdT-cell: 1.6;naive CD8 T-cell: 1.5" "Lineage enriched" "Detected in single" 16 "T-cells: 1.6" "Not detected" "Not detected" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 59: Leukemia - T-cell receptor" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" "unprognostic (2.05e-1)" TTC17 FLJ10890 ENSG00000052841 "Tetratricopeptide repeat domain 17" Q96AE7 11 43358920-43494933 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038508 Approved Supported "Plasma membrane,Cytosol" "Intracellular and membrane" Other NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 60: Stomach - Digestion" "Cluster 6: Non-specific - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 7: Non-specific - Transcription" 31 "Plasma membrane" Cytosol "HPA038508: " "unprognostic (3.26e-1)" "unprognostic (8.01e-2)" "unprognostic (2.25e-1)" "unprognostic (8.55e-3)" "unprognostic (1.34e-1)" "unprognostic (1.76e-2)" "unprognostic (3.47e-1)" "unprognostic (5.34e-3)" "unprognostic (3.36e-1)" "unprognostic (9.35e-2)" "unprognostic (7.11e-3)" "unprognostic (4.16e-3)" "unprognostic (5.67e-3)" "unprognostic (1.03e-1)" "unprognostic (3.17e-1)" "unprognostic (2.46e-1)" "potential prognostic unfavorable (8.03e-4)" "unprognostic (1.61e-1)" "unprognostic (2.60e-1)" "unprognostic (7.54e-2)" "unprognostic (2.16e-1)" "unprognostic (2.74e-1)" "potential prognostic unfavorable (5.20e-4)" "unprognostic (1.69e-2)" "unprognostic (2.10e-3)" "unprognostic (4.84e-2)" "unprognostic (5.33e-2)" "unprognostic (9.69e-2)" "unprognostic (1.55e-1)" "unprognostic (3.55e-2)" "unprognostic (5.70e-2)" TTC19 "FLJ20343, MGC19520" ENSG00000011295 "Tetratricopeptide repeat domain 19" Q6DKK2 17 15999784-16045015 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Electron transport, Respiratory chain, Transport" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 5.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023010, HPA052380" Enhanced Enhanced Mitochondria NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 70: Non-specific - Protein processing" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 42: Non-specific - Unknown function" "Cluster 103: Non-specific - Basic cellular processes" 55 Mitochondria "HPA023010: , HPA052380: " "unprognostic (8.81e-3)" "unprognostic (1.37e-2)" "unprognostic (2.52e-1)" "unprognostic (2.16e-2)" "unprognostic (1.50e-1)" "unprognostic (4.42e-2)" "unprognostic (8.06e-2)" "unprognostic (4.85e-3)" "unprognostic (4.85e-1)" "unprognostic (4.95e-3)" "unprognostic (1.81e-1)" "unprognostic (3.53e-2)" "unprognostic (2.10e-3)" "unprognostic (7.43e-3)" "unprognostic (1.90e-2)" "unprognostic (1.84e-1)" "unprognostic (2.65e-1)" "unprognostic (5.30e-2)" "unprognostic (3.72e-1)" "unprognostic (2.43e-1)" "unprognostic (6.39e-2)" "unprognostic (3.20e-2)" "unprognostic (2.90e-2)" "unprognostic (5.50e-3)" "unprognostic (1.05e-1)" "unprognostic (1.65e-1)" "unprognostic (4.21e-2)" "unprognostic (1.06e-1)" "unprognostic (2.40e-1)" "unprognostic (2.28e-2)" "unprognostic (5.48e-3)" TTC21A "IFT139A, STI2, Thm2" ENSG00000168026 "Tetratricopeptide repeat domain 21A" Q8NDW8 3 39107680-39138903 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 43.1" "Cell type enhanced" "Detected in many" "Early spermatids: 128.3;Endometrial ciliated cells: 89.7;Ependymal cells: 156.0;Fallopian tube ciliated cells: 132.2;Late primary spermatocytes: 161.3;Late spermatids: 132.2;Respiratory ciliated cells: 256.0;Thyrotrophs: 84.2" "Cell type enhanced" "Detected in all" "ependymal cell: 156.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells, Spleen - B-cells (Spleen), Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA035510, HPA035511" Enhanced Approved Nucleoplasm NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 57: Testis - Spermatogenesis" "Cluster 17: Choroid plexus - Cilium" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 34: Ciliated cells - Cilia assembly & function" 4 Nucleoplasm "HPA035510: , HPA035511: " "unprognostic (1.17e-1)" "unprognostic (3.90e-1)" "unprognostic (4.57e-2)" "unprognostic (4.39e-2)" "unprognostic (2.42e-2)" TTC21B "FAP60, FLA17, FLJ11457, IFT139, IFT139B, JBTS11, NPHP12, THM1" ENSG00000123607 "Tetratricopeptide repeat domain 21B" Q7Z4L5 2 165857475-165953851 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant, Intellectual disability, Joubert syndrome, Meckel syndrome, Nephronophthisis, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial ciliated cells: 310.4;Fallopian tube ciliated cells: 256.7;Respiratory ciliated cells: 291.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073293 Supported Approved "Primary cilium,Centriolar satellite,Basal body,Cytosol,Connecting piece,Mid piece,Principal piece,End piece" NA No "Cluster 14: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 2: Neurons - Nucleosome" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 107: Ciliated cells - Cilia assembly & function" 16 "Primary cilium, Centriolar satellite, Basal body" "Cytosol, Connecting piece, Mid piece, Principal piece, End piece" "HPA073293: " "unprognostic (1.35e-1)" "unprognostic (2.03e-3)" "unprognostic (2.03e-1)" "unprognostic (1.16e-1)" "unprognostic (1.68e-1)" "unprognostic (1.48e-1)" "unprognostic (1.13e-1)" "unprognostic (5.25e-2)" "unprognostic (3.23e-1)" "unprognostic (4.52e-2)" "validated prognostic favorable (5.35e-6)" "validated prognostic favorable (2.28e-4)" "unprognostic (6.59e-2)" "unprognostic (2.77e-3)" "unprognostic (1.28e-1)" "unprognostic (9.44e-2)" "unprognostic (1.68e-1)" "unprognostic (3.38e-1)" "unprognostic (1.17e-1)" "unprognostic (2.11e-2)" "unprognostic (3.36e-1)" "unprognostic (2.86e-1)" "unprognostic (3.90e-3)" "unprognostic (3.68e-1)" "unprognostic (2.25e-1)" "unprognostic (2.45e-3)" "unprognostic (2.61e-1)" "unprognostic (6.86e-2)" "unprognostic (1.43e-1)" "unprognostic (3.10e-2)" "unprognostic (4.20e-2)" TTC22 FLJ20619 ENSG00000006555 "Tetratricopeptide repeat domain 22" Q5TAA0 1 54779712-54801323 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 38.0;esophagus: 104.7;vagina: 45.7" "Cell type enriched" "Detected in many" 5 "Esophageal apical cells: 689.8" "Cell type enhanced" "Detected in many" "eccentric medium spiny neuron: 7.3;leukocyte: 10.1;medium spiny neuron: 8.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Skin - Keratinocyte (other), Spleen - T-cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" "Region enhanced" "Detected in single" "hippocampal formation: 1.7" HPA035072 Uncertain NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 7: Liver cancer - Metabolism" "Cluster 84: Apical squamous epithelium - Cornification" "HPA035072: " "unprognostic (2.06e-1)" "unprognostic (2.13e-3)" "unprognostic (4.30e-2)" "unprognostic (1.97e-1)" "unprognostic (3.50e-3)" "unprognostic (1.05e-1)" "unprognostic (3.76e-2)" "unprognostic (1.29e-1)" "potential prognostic favorable (1.48e-5)" "unprognostic (1.07e-3)" "potential prognostic favorable (1.52e-5)" "potential prognostic unfavorable (7.44e-4)" "unprognostic (2.69e-2)" "unprognostic (2.18e-2)" "unprognostic (2.26e-1)" "unprognostic (3.22e-1)" "unprognostic (5.82e-2)" "unprognostic (6.80e-2)" "unprognostic (5.30e-2)" "unprognostic (4.22e-2)" "unprognostic (2.18e-2)" "unprognostic (2.06e-1)" "unprognostic (1.62e-2)" "unprognostic (1.00e-1)" "unprognostic (8.84e-2)" "unprognostic (2.33e-2)" "unprognostic (1.60e-2)" "unprognostic (7.51e-2)" "unprognostic (1.13e-2)" TTC23 "FLJ12572, HCC-8" ENSG00000103852 "Tetratricopeptide repeat domain 23" Q5W5X9 15 99136323-99251223 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 230.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.8" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039806, HPA040369" Uncertain Approved "Primary cilium transition zone,Cytosol" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 55: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 18 Cytosol "Primary cilium transition zone" "HPA039806: , HPA040369: " "unprognostic (8.89e-2)" "unprognostic (5.78e-2)" "unprognostic (2.74e-2)" "unprognostic (1.00e-1)" "unprognostic (3.67e-1)" "unprognostic (3.66e-1)" "unprognostic (6.12e-2)" "unprognostic (4.75e-2)" "unprognostic (1.36e-1)" "unprognostic (1.29e-2)" "potential prognostic favorable (1.83e-4)" "unprognostic (1.84e-2)" "unprognostic (1.72e-1)" "unprognostic (5.83e-2)" "unprognostic (3.78e-1)" "unprognostic (1.47e-1)" "unprognostic (1.77e-2)" "unprognostic (7.11e-2)" "unprognostic (1.61e-1)" "unprognostic (7.36e-2)" "unprognostic (1.76e-1)" "unprognostic (1.47e-2)" "unprognostic (8.12e-3)" "unprognostic (1.08e-1)" "unprognostic (3.24e-2)" "unprognostic (2.59e-2)" "unprognostic (1.35e-1)" "unprognostic (1.40e-2)" "unprognostic (2.68e-1)" "unprognostic (9.46e-2)" "unprognostic (3.25e-1)" TTC23L FLJ25439 ENSG00000205838 "Tetratricopeptide repeat domain 23 like" Q6PF05 5 34838833-34900511 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 25.2" "Cell type enhanced" "Detected in many" "Breast lactating cells: 240.0;Choroid plexus epithelial cells: 96.1;Early spermatids: 517.6;Ependymal cells: 308.0;Fallopian tube ciliated cells: 107.0;Late primary spermatocytes: 234.4;Late spermatids: 293.5;Pituicytes/FSCs: 158.3;Respiratory ciliated cells: 202.2" "Cell type enriched" "Detected in many" 4 "ependymal cell: 317.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary gland ductal cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA037807 Enhanced NA NA "Cluster 47: Testis - Mixed function" "Cluster 46: Brainstem - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 23 "HPA037807: " "unprognostic (5.58e-2)" "unprognostic (6.12e-3)" TTC24 ENSG00000187862 "Tetratricopeptide repeat domain 24" A2A3L6 1 156579723-156587719 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "lymphoid tissue: 19.7" "Cell type enhanced" "Detected in some" "B-cells: 6.5;Gonadotrophs: 6.1;Hematopoietic stem cells: 9.2;Innate lymphoid cells: 4.5;Myosatellite cells: 3.3;pDCs: 41.6;Platelets: 2.8;T-cells: 4.6;Thymocytes: 14.4" "Cell type enhanced" "Detected in single" "deep-layer near-projecting: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "NK-cell: 3.7;plasmacytoid DC: 12.4" "Group enriched" "Detected in many" 4 "dendritic cells: 12.4;NK-cells: 3.7" "Group enriched" "Detected in some" 14 "Leukemia: 7.0;lymphoma: 3.2" "Adipose subcutaneous - T-cells, Adrenal gland - T-cells, Breast - T-cells, Kidney - T-cells, Minor Salivary Gland - T-cells, Pituitary gland - Gonadotropes, Prostate - T-cells, Thyroid gland - T-cells" "Low region specificity" "Detected in all" HPA029799 Approved Nucleoplasm NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 80: Thymus - Adaptive immune response" "Cluster 53: Neurons - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" Nucleoplasm "HPA029799: " "unprognostic (4.26e-2)" TTC26 "dyf-13, DYF13, FLJ12571, IFT56" ENSG00000105948 "Tetratricopeptide repeat domain 26" A0AVF1 7 139133744-139191986 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 106.4;Early primary spermatocytes: 85.2;Endometrial ciliated cells: 128.5;Ependymal cells: 202.7;Epididymal efferent duct ciliated cells: 113.3;Fallopian tube ciliated cells: 161.0;Late primary spermatocytes: 105.4;Respiratory ciliated cells: 254.7" "Cell type enhanced" "Detected in all" "ependymal cell: 215.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036338, HPA061867" Enhanced Approved "Nucleoplasm,Primary cilium,Mitochondria,Cytosol" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 39: Non-specific - Transcription" "Cluster 34: Ciliated cells - Cilia assembly & function" 51 Nucleoplasm "Primary cilium, Mitochondria, Cytosol" "HPA036338: , HPA061867: " "unprognostic (3.41e-1)" "unprognostic (3.37e-1)" "unprognostic (7.46e-3)" "unprognostic (5.11e-2)" "unprognostic (2.42e-1)" "unprognostic (7.01e-2)" "unprognostic (1.10e-2)" "potential prognostic unfavorable (2.24e-4)" "unprognostic (2.12e-1)" "unprognostic (5.65e-3)" "potential prognostic favorable (6.42e-4)" "unprognostic (1.07e-1)" "unprognostic (2.22e-1)" "unprognostic (5.03e-3)" "unprognostic (8.54e-2)" "unprognostic (2.51e-2)" "unprognostic (3.42e-2)" "unprognostic (3.29e-1)" "unprognostic (2.61e-1)" "unprognostic (2.18e-2)" "unprognostic (9.47e-2)" "unprognostic (2.42e-1)" "unprognostic (2.20e-1)" "unprognostic (1.41e-2)" "unprognostic (1.46e-1)" "unprognostic (2.79e-2)" "unprognostic (7.31e-2)" "unprognostic (2.58e-1)" "unprognostic (4.46e-2)" "unprognostic (1.04e-1)" TTC27 FLJ20272 ENSG00000018699 "Tetratricopeptide repeat domain 27" Q6P3X3 2 32628032-32821051 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Megakaryocyte progenitors: 309.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031246 Approved Approved Nucleoli,Mitochondria No No "Cluster 43: Non-specific - Transcription & Translation" "Cluster 57: Testis - Spermatogenesis" "Cluster 11: White matter - Signal transduction" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 7: Non-specific - Transcription" 31 Mitochondria Nucleoli "HPA031246: " "unprognostic (1.29e-1)" "unprognostic (1.29e-2)" "unprognostic (2.94e-1)" "unprognostic (4.58e-2)" "unprognostic (6.40e-2)" "unprognostic (1.34e-1)" "unprognostic (1.93e-1)" "unprognostic (2.70e-1)" "unprognostic (2.21e-1)" "unprognostic (1.53e-2)" "potential prognostic favorable (1.71e-6)" "unprognostic (2.71e-2)" "unprognostic (3.97e-2)" "validated prognostic unfavorable (1.14e-5)" "validated prognostic unfavorable (7.01e-4)" "unprognostic (2.25e-2)" "unprognostic (3.62e-3)" "unprognostic (2.29e-1)" "unprognostic (1.48e-1)" "unprognostic (3.85e-3)" "unprognostic (2.16e-2)" "validated prognostic unfavorable (3.24e-4)" "validated prognostic unfavorable (8.93e-5)" "unprognostic (1.01e-1)" "unprognostic (1.17e-2)" "unprognostic (7.17e-3)" "unprognostic (6.26e-2)" "unprognostic (1.06e-1)" "unprognostic (3.20e-1)" "unprognostic (1.68e-2)" "unprognostic (1.37e-1)" TTC28 KIAA1043 ENSG00000100154 "Tetratricopeptide repeat domain 28" Q96AY4 22 27978014-28679840 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibro-adipogenic progenitors: 907.5;Proximal tubule cells: 897.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Spleen - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001080 Approved "Microtubules,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes NA "Cluster 75: Ovary - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 9 "Microtubules, Cytokinetic bridge, Mitotic spindle" Cytosol "HPA001080: " "potential prognostic favorable (9.62e-4)" "unprognostic (3.06e-1)" "unprognostic (3.48e-3)" "unprognostic (1.49e-2)" "unprognostic (3.84e-2)" "unprognostic (1.22e-1)" "unprognostic (4.18e-2)" "unprognostic (9.70e-2)" "unprognostic (4.56e-2)" "unprognostic (9.27e-3)" "validated prognostic favorable (9.65e-10)" "validated prognostic favorable (1.22e-4)" "unprognostic (5.56e-2)" "unprognostic (2.66e-1)" "unprognostic (2.77e-2)" "unprognostic (1.39e-2)" "unprognostic (1.52e-1)" "unprognostic (1.10e-2)" "unprognostic (3.74e-3)" "unprognostic (1.30e-1)" "unprognostic (1.70e-1)" "unprognostic (8.14e-2)" "unprognostic (9.96e-2)" "unprognostic (1.90e-1)" "unprognostic (1.66e-1)" "unprognostic (8.54e-2)" "unprognostic (2.83e-2)" "unprognostic (1.80e-2)" "unprognostic (1.02e-1)" "unprognostic (4.46e-3)" "unprognostic (3.53e-2)" TTC29 NYD-SP14 ENSG00000137473 "Tetratricopeptide repeat domain 29" Q8NA56 4 146706617-146945882 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "fallopian tube: 18.8;testis: 67.2" "Group enriched" "Detected in many" 5 "Early spermatids: 687.2;Endometrial ciliated cells: 337.4;Ependymal cells: 1066.1;Epididymal efferent duct ciliated cells: 420.5;Fallopian tube ciliated cells: 431.5;Late primary spermatocytes: 823.5;Late spermatids: 633.1;Respiratory ciliated cells: 839.5" "Cell type enriched" "Detected in many" 9 "ependymal cell: 1149.1" "Cancer enhanced" "Detected in single" "Uterine Corpus Endometrial Carcinoma (TCGA): 1.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA037006, HPA061473" Uncertain Supported "Principal piece" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" "Principal piece" "HPA037006: , HPA061473: " "unprognostic (3.97e-1)" "unprognostic (5.58e-1)" "unprognostic (1.12e-1)" "unprognostic (1.94e-1)" TTC3 "DCRR1, RNF105, TPRD, TPRDI, TPRDII, TPRDIII" ENSG00000182670 "Tetratricopeptide repeat domain 3" P53804 21 37073226-37203112 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Gonadotrophs: 1171.9;Lactotrophs: 1476.3;Somatotrophs: 1773.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016810, HPA023964, HPA036304" Uncertain Approved Nucleoplasm,Nucleoli,Cytosol No No "Cluster 30: Non-specific - DNA binding" "Cluster 22: Epididymis - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 11 "Nucleoplasm, Nucleoli" Cytosol "HPA016810: , HPA023964: , HPA036304: " "unprognostic (1.03e-1)" "unprognostic (2.54e-2)" "unprognostic (1.02e-1)" "unprognostic (1.28e-1)" "unprognostic (1.46e-1)" "unprognostic (1.05e-1)" "unprognostic (2.33e-1)" "unprognostic (3.79e-3)" "unprognostic (3.94e-2)" "unprognostic (2.93e-1)" "potential prognostic favorable (2.32e-4)" "unprognostic (3.50e-2)" "unprognostic (2.95e-1)" "unprognostic (1.38e-1)" "unprognostic (2.62e-1)" "unprognostic (2.23e-2)" "unprognostic (3.34e-1)" "unprognostic (8.21e-3)" "unprognostic (2.47e-1)" "unprognostic (5.12e-2)" "unprognostic (2.33e-2)" "unprognostic (2.19e-1)" "unprognostic (9.68e-2)" "unprognostic (2.08e-1)" "unprognostic (5.64e-2)" "unprognostic (3.14e-1)" "unprognostic (2.07e-1)" "unprognostic (2.10e-2)" "unprognostic (2.18e-1)" "unprognostic (2.30e-2)" "unprognostic (4.20e-2)" TTC30A "FAP259, FLJ13946, IFT70A" ENSG00000197557 "Tetratricopeptide repeat domain 30A" Q86WT1 2 177612999-177618742 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 34.6;Fallopian tube ciliated cells: 20.6;Late primary spermatocytes: 122.7;Respiratory ciliated cells: 31.9" "Cell type enhanced" "Detected in many" "ependymal cell: 17.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "HPA051714, HPA052100, HPA052487" Supported Approved "Nucleoplasm,Primary cilium,Primary cilium tip,Centrosome,Basal body" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 59 "Primary cilium, Centrosome, Basal body" "Nucleoplasm, Primary cilium tip" "HPA051714: , HPA052100: , HPA052487: " "unprognostic (4.60e-1)" "unprognostic (1.09e-1)" "unprognostic (4.22e-2)" "unprognostic (7.38e-2)" "unprognostic (1.40e-1)" "unprognostic (2.25e-2)" "unprognostic (1.27e-2)" "unprognostic (1.07e-2)" "unprognostic (3.81e-2)" "unprognostic (5.83e-3)" "potential prognostic favorable (2.24e-5)" "unprognostic (9.25e-2)" "unprognostic (1.12e-1)" "unprognostic (1.83e-2)" "unprognostic (3.93e-2)" "unprognostic (1.74e-1)" "unprognostic (9.82e-2)" "unprognostic (1.46e-1)" "unprognostic (1.17e-2)" "unprognostic (1.67e-1)" "unprognostic (2.23e-1)" "unprognostic (1.69e-1)" "unprognostic (1.29e-1)" "unprognostic (5.40e-2)" "unprognostic (5.24e-2)" "unprognostic (1.62e-2)" "unprognostic (8.90e-2)" "unprognostic (5.90e-3)" "unprognostic (1.47e-1)" "potential prognostic unfavorable (5.92e-4)" "unprognostic (1.04e-1)" TTC30B "fleer, FLJ30990, IFT70B" ENSG00000196659 "Tetratricopeptide repeat domain 30B" Q8N4P2 2 177548998-177552796 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 17.4;Early primary spermatocytes: 15.3;Endometrial ciliated cells: 16.6;Ependymal cells: 18.0;Fallopian tube ciliated cells: 33.7;Late primary spermatocytes: 30.3;Respiratory ciliated cells: 54.0" "Cell type enriched" "Detected in many" 5 "ependymal cell: 25.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "HPA051714, HPA052100, HPA052487" Supported Approved "Nucleoplasm,Primary cilium,Primary cilium tip,Centrosome,Basal body" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 22: Epididymis - Mixed function" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" 84 "Primary cilium, Centrosome, Basal body" "Nucleoplasm, Primary cilium tip" "HPA051714: , HPA052100: , HPA052487: " "unprognostic (4.81e-2)" "unprognostic (1.29e-1)" "unprognostic (1.15e-1)" "unprognostic (2.47e-1)" "unprognostic (1.66e-1)" "unprognostic (1.03e-1)" "unprognostic (3.60e-2)" "unprognostic (3.90e-3)" "unprognostic (2.59e-1)" "unprognostic (1.15e-2)" "potential prognostic favorable (5.42e-5)" "unprognostic (1.71e-2)" "unprognostic (2.13e-1)" "unprognostic (8.15e-3)" "unprognostic (1.87e-2)" "unprognostic (2.57e-1)" "unprognostic (9.79e-2)" "unprognostic (1.32e-1)" "unprognostic (1.05e-3)" "unprognostic (3.50e-1)" "unprognostic (5.64e-2)" "unprognostic (1.85e-1)" "unprognostic (3.24e-1)" "unprognostic (1.01e-1)" "unprognostic (7.14e-3)" "unprognostic (1.54e-1)" "unprognostic (1.15e-1)" "unprognostic (2.02e-1)" "unprognostic (2.00e-1)" "unprognostic (1.80e-2)" "unprognostic (5.95e-2)" TTC31 FLJ12788 ENSG00000115282 "Tetratricopeptide repeat domain 31" Q49AM3 2 74483073-74494559 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" HPA041783 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 30: White matter - Myelination" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 79: Photoreceptor cells - Phototransduction" 1 Cytosol Nucleoplasm "HPA041783: " "unprognostic (6.30e-2)" "unprognostic (2.01e-1)" "unprognostic (1.05e-1)" "unprognostic (6.75e-2)" "unprognostic (3.81e-2)" "unprognostic (1.61e-1)" "unprognostic (2.72e-1)" "unprognostic (1.09e-1)" "unprognostic (1.44e-1)" "unprognostic (4.73e-2)" "unprognostic (1.11e-3)" "unprognostic (5.63e-2)" "unprognostic (1.27e-1)" "unprognostic (9.77e-2)" "unprognostic (1.88e-2)" "unprognostic (2.57e-1)" "unprognostic (2.24e-1)" "unprognostic (1.05e-1)" "unprognostic (2.81e-2)" "unprognostic (5.13e-2)" "unprognostic (1.86e-1)" "unprognostic (9.58e-2)" "unprognostic (2.54e-3)" "unprognostic (3.96e-2)" "unprognostic (2.06e-1)" "unprognostic (6.04e-2)" "unprognostic (1.97e-1)" "unprognostic (2.42e-1)" "unprognostic (2.63e-1)" "unprognostic (3.15e-1)" "unprognostic (2.82e-2)" TTC32 ENSG00000183891 "Tetratricopeptide repeat domain 32" Q5I0X7 2 19896631-19901983 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 102.9;Epididymal principal cells: 89.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036024 Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 40: Non-specific - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 7 Mitochondria Nucleoplasm "HPA036024: " "unprognostic (2.99e-1)" "unprognostic (2.56e-2)" "unprognostic (3.34e-1)" "unprognostic (2.44e-2)" "unprognostic (6.58e-3)" "unprognostic (1.40e-2)" "unprognostic (1.34e-1)" "unprognostic (1.59e-2)" "unprognostic (1.33e-1)" "unprognostic (2.60e-1)" "unprognostic (1.56e-1)" "unprognostic (2.54e-1)" "unprognostic (2.36e-1)" "unprognostic (9.25e-2)" "unprognostic (5.23e-2)" "unprognostic (2.30e-2)" "unprognostic (3.20e-1)" "unprognostic (1.06e-2)" "unprognostic (5.46e-2)" "unprognostic (4.70e-3)" "unprognostic (4.97e-2)" "unprognostic (1.16e-2)" "potential prognostic unfavorable (2.81e-4)" "unprognostic (4.85e-2)" "unprognostic (2.17e-1)" "unprognostic (2.95e-2)" "unprognostic (1.06e-3)" "unprognostic (1.09e-1)" "unprognostic (2.56e-1)" "unprognostic (6.16e-3)" "unprognostic (1.18e-2)" TTC33 OSRF ENSG00000113638 "Tetratricopeptide repeat domain 33" Q6PID6 5 40512333-40755963 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Platelets: 132.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038252, HPA038253" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 31: Non-specific - Transcription" "Cluster 29: Non-specific - Unknown function" "Cluster 9: T-cells - Adaptive immunity: Regulation" 39 Nucleoplasm "Golgi apparatus, Vesicles" "HPA038252: , HPA038253: " "unprognostic (3.10e-1)" "unprognostic (2.00e-1)" "potential prognostic unfavorable (7.54e-4)" "unprognostic (2.22e-1)" "unprognostic (1.69e-1)" "unprognostic (1.65e-2)" "unprognostic (1.95e-1)" "unprognostic (1.74e-1)" "unprognostic (2.05e-1)" "unprognostic (8.77e-2)" "potential prognostic favorable (1.90e-7)" "unprognostic (7.33e-3)" "unprognostic (1.80e-1)" "unprognostic (9.48e-3)" "unprognostic (9.87e-2)" "unprognostic (2.68e-2)" "unprognostic (3.91e-1)" "unprognostic (2.50e-2)" "unprognostic (1.27e-1)" "unprognostic (1.19e-1)" "potential prognostic unfavorable (9.06e-6)" "unprognostic (2.65e-2)" "unprognostic (4.10e-2)" "unprognostic (4.16e-1)" "unprognostic (3.49e-2)" "unprognostic (1.01e-1)" "unprognostic (2.24e-1)" "unprognostic (1.44e-1)" "unprognostic (2.46e-1)" "unprognostic (1.36e-2)" "unprognostic (2.86e-1)" TTC34 ENSG00000215912 "Tetratricopeptide repeat domain 34" A8MYJ7 1 2636986-2801693 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 5.4" "Cell type enriched" "Detected in some" 11 "Ependymal cells: 250.0" "Cell type enriched" "Detected in many" 17 "ependymal cell: 223.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA066832 Uncertain NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 34: Ciliated cells - Cilia assembly & function" "HPA066832: " "unprognostic (9.65e-2)" TTC36 HBP21 ENSG00000172425 "Tetratricopeptide repeat domain 36" A6NLP5 11 118527472-118531197 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "liver: 235.3" "Group enriched" "Detected in many" 9 "Enterocytes: 164.1;Epididymal principal cells: 382.3;Hepatocytes: 586.8" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in some" 16 "Breast Invasive Carcinoma (TCGA): 12.4;Liver Hepatocellular Carcinoma (TCGA): 28.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 1.7;prostate cancer: 1.3" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" HPA038731 Enhanced Uncertain Nucleoplasm NA NA 71000 "Cluster 53: Liver - Plasma proteins" "Cluster 25: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 1 Nucleoplasm "HPA038731: " "unprognostic (1.44e-3)" "unprognostic (2.50e-1)" "unprognostic (1.22e-2)" "unprognostic (7.45e-2)" "unprognostic (1.67e-3)" "validated prognostic favorable (3.19e-5)" "validated prognostic favorable (1.72e-4)" "unprognostic (2.56e-1)" "unprognostic (3.58e-1)" TTC38 FLJ20699 ENSG00000075234 "Tetratricopeptide repeat domain 38" Q5R3I4 22 46267961-46294008 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 226.4" "Cell type enhanced" "Detected in many" "Colonocytes: 86.8;Enterocytes: 196.5;Hepatocytes: 235.1;NK-cells: 132.0;Proximal tubule cells: 191.5" "Cell type enhanced" "Detected in many" "leukocyte: 53.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "gdT-cell: 90.7" "Group enriched" "Detected in all" 4 "granulocytes: 30.0;NK-cells: 38.1;T-cells: 90.7" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029302, HPA075893" Approved Approved Cytosol NA NA 270000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 46: Brainstem - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 3 Cytosol "HPA029302: , HPA075893: " "unprognostic (1.47e-1)" "unprognostic (5.79e-2)" "unprognostic (1.64e-1)" "unprognostic (2.17e-1)" "unprognostic (1.47e-3)" "potential prognostic favorable (7.14e-4)" "unprognostic (9.34e-2)" "unprognostic (2.17e-3)" "unprognostic (2.36e-2)" "unprognostic (1.44e-1)" "potential prognostic favorable (6.18e-7)" "unprognostic (7.74e-3)" "unprognostic (2.06e-2)" "unprognostic (5.48e-2)" "potential prognostic favorable (4.78e-4)" "unprognostic (2.99e-1)" "unprognostic (2.27e-1)" "unprognostic (1.63e-1)" "unprognostic (1.40e-1)" "unprognostic (1.59e-2)" "unprognostic (1.62e-1)" "unprognostic (2.84e-1)" "unprognostic (2.97e-1)" "unprognostic (9.37e-2)" "unprognostic (5.44e-3)" "unprognostic (8.68e-2)" "unprognostic (2.85e-1)" "unprognostic (1.12e-1)" "unprognostic (1.61e-1)" "unprognostic (8.26e-2)" "unprognostic (1.69e-2)" TTC39A "C1orf34, DEME-6, KIAA0452" ENSG00000085831 "Tetratricopeptide repeat domain 39A" Q5SRH9 1 51287258-51345116 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 52.8" "Cell type enhanced" "Detected in many" "Early spermatids: 492.0;Late primary spermatocytes: 215.2;Late spermatids: 910.8" "Cell type enhanced" "Detected in many" "thalamic excitatory: 35.5" "Cancer enhanced" "Detected in all" "Breast Invasive Carcinoma (TCGA): 101.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 47 "plasmacytoid DC: 31.8" "Lineage enriched" "Detected in single" 47 "dendritic cells: 31.8" "Cancer enhanced" "Detected in many" "breast cancer: 65.1" "Breast - Breast glandular cells, Colon - Colon enterocytes, Heart muscle - Cardiomyocytes, Kidney - Macrophages, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA028098, HPA043440" Uncertain Enhanced Centrosome NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 21: Testis - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" Centrosome "HPA028098: , HPA043440: " "unprognostic (7.56e-2)" "unprognostic (2.89e-2)" "unprognostic (7.99e-2)" "unprognostic (2.09e-1)" "potential prognostic favorable (5.25e-4)" "unprognostic (2.29e-1)" "unprognostic (2.00e-3)" "unprognostic (1.29e-2)" "unprognostic (1.63e-2)" "unprognostic (1.50e-1)" "unprognostic (2.17e-2)" "unprognostic (1.76e-1)" "unprognostic (7.44e-2)" "potential prognostic unfavorable (1.27e-4)" "unprognostic (1.07e-3)" "unprognostic (8.86e-2)" "unprognostic (1.64e-1)" "unprognostic (1.44e-2)" "unprognostic (1.98e-1)" "unprognostic (9.97e-2)" "unprognostic (5.37e-2)" "unprognostic (1.16e-1)" "unprognostic (3.89e-2)" "unprognostic (1.42e-1)" "unprognostic (2.88e-1)" "unprognostic (5.79e-2)" "unprognostic (2.78e-1)" "unprognostic (2.07e-2)" "unprognostic (1.19e-1)" "unprognostic (1.20e-1)" "unprognostic (1.66e-1)" TTC39B "C9orf52, FLJ33868" ENSG00000155158 "Tetratricopeptide repeat domain 39B" Q5VTQ0 9 15163622-15307360 "Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubule cells: 186.1;Renal collecting duct intercalated cells: 206.7;Thyrotrophs: 214.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "NK-cells: 8.1;T-cells: 7.4" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063162 Approved "Endoplasmic reticulum" NA NA "Cluster 27: T-cells - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 37: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 58: Mast cells - Allergic inflammatory responses" 3 "Endoplasmic reticulum" "HPA063162: " "unprognostic (1.56e-1)" "unprognostic (1.51e-1)" "unprognostic (3.96e-1)" "unprognostic (3.28e-1)" "unprognostic (3.42e-2)" "unprognostic (1.72e-2)" "unprognostic (3.71e-1)" "unprognostic (2.59e-3)" "unprognostic (7.08e-2)" "unprognostic (3.52e-2)" "potential prognostic favorable (7.09e-6)" "unprognostic (1.63e-3)" "unprognostic (5.35e-3)" "unprognostic (2.63e-2)" "unprognostic (1.23e-3)" "unprognostic (9.52e-3)" "unprognostic (8.04e-3)" "unprognostic (8.43e-3)" "unprognostic (8.60e-2)" "unprognostic (8.10e-2)" "unprognostic (3.65e-2)" "unprognostic (1.41e-1)" "unprognostic (3.83e-1)" "unprognostic (7.00e-2)" "potential prognostic favorable (4.64e-4)" "unprognostic (1.86e-3)" "unprognostic (8.91e-2)" "unprognostic (1.54e-2)" "unprognostic (9.20e-2)" "unprognostic (7.19e-2)" "unprognostic (3.71e-1)" TTC39C "C18orf17, FLJ33761, HsT2697" ENSG00000168234 "Tetratricopeptide repeat domain 39C" Q8N584 18 23992773-24135610 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 87.8;retina: 132.5" "Cell type enhanced" "Detected in many" "Late spermatids: 504.8;Rod photoreceptor cells: 1430.0;Sertoli cells: 540.6;T-cells: 361.6" "Cell type enhanced" "Detected in all" "leukocyte: 497.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 115.6" "Lineage enriched" "Detected in all" 4 "T-cells: 115.6" "Low cancer specificity" "Detected in all" "Heart muscle - Macrophages, Pituitary gland - Lactotropes, Skin - Keratinocyte (other), Spleen - T-cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065705, HPA065713" Approved Approved Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 42: Retina - Visual perception" "Cluster 29: Forebrain - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" Nucleoplasm "HPA065705: , HPA065713: " "unprognostic (4.63e-2)" "potential prognostic favorable (1.53e-6)" "unprognostic (2.33e-1)" "unprognostic (2.22e-2)" "unprognostic (9.27e-2)" "unprognostic (3.98e-2)" "unprognostic (6.22e-2)" "unprognostic (5.97e-2)" "unprognostic (2.02e-2)" "unprognostic (3.55e-2)" "potential prognostic unfavorable (7.88e-6)" "unprognostic (3.10e-1)" "unprognostic (1.96e-2)" "unprognostic (4.98e-2)" "unprognostic (9.81e-2)" "potential prognostic favorable (3.58e-4)" "unprognostic (4.21e-2)" "unprognostic (1.14e-2)" "unprognostic (1.43e-2)" "unprognostic (1.98e-1)" "unprognostic (7.46e-3)" "unprognostic (1.19e-1)" "unprognostic (1.62e-1)" "unprognostic (1.70e-1)" "unprognostic (4.10e-1)" "potential prognostic favorable (7.34e-4)" "unprognostic (3.15e-1)" "unprognostic (1.30e-1)" "unprognostic (1.59e-1)" "unprognostic (1.50e-2)" "unprognostic (8.23e-2)" TTC4 "CNS1, FLJ41930, MGC5097" ENSG00000243725 "Tetratricopeptide repeat domain 4" O95801 1 54715861-54742657 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 6.5;Thyrotrophs: 7.3" "Cell type enhanced" "Detected in many" "astrocyte: 5.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041608, HPA042459" Approved Enhanced "Intermediate filaments,Cytoplasmic bodies" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 37: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 29 "Intermediate filaments" "Cytoplasmic bodies" "HPA041608: , HPA042459: " "unprognostic (1.95e-2)" "unprognostic (8.62e-2)" "unprognostic (2.70e-2)" "unprognostic (9.30e-3)" "unprognostic (2.19e-2)" "unprognostic (2.06e-2)" "unprognostic (3.49e-1)" "potential prognostic favorable (3.56e-4)" "unprognostic (2.82e-1)" "unprognostic (1.78e-1)" "unprognostic (3.58e-3)" "unprognostic (1.54e-1)" "unprognostic (1.48e-1)" "potential prognostic unfavorable (5.91e-6)" "unprognostic (4.07e-3)" "unprognostic (2.56e-2)" "potential prognostic unfavorable (8.34e-4)" "unprognostic (1.07e-1)" "unprognostic (1.28e-1)" "unprognostic (1.13e-1)" "unprognostic (2.73e-1)" "unprognostic (4.54e-2)" "unprognostic (2.01e-1)" "unprognostic (3.03e-1)" "unprognostic (7.44e-2)" "unprognostic (2.72e-1)" "unprognostic (1.27e-1)" "unprognostic (1.85e-1)" "unprognostic (2.42e-1)" "unprognostic (3.47e-3)" "unprognostic (1.40e-1)" TTC5 Strap ENSG00000136319 "Tetratricopeptide repeat domain 5" Q8N0Z6 14 20256558-20305960 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fallopian tube ciliated cells: 77.4;Respiratory ciliated cells: 74.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045008, HPA054198" Approved Supported Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 7: Non-specific - Transcription" 12 Nucleoplasm "HPA045008: , HPA054198: " "unprognostic (7.34e-2)" "unprognostic (4.17e-2)" "unprognostic (1.76e-2)" "unprognostic (8.44e-2)" "unprognostic (3.16e-1)" "unprognostic (6.91e-2)" "unprognostic (2.10e-3)" "unprognostic (1.88e-2)" "unprognostic (7.37e-2)" "unprognostic (8.78e-2)" "potential prognostic favorable (3.28e-5)" "unprognostic (3.56e-3)" "unprognostic (1.17e-2)" "unprognostic (5.15e-2)" "unprognostic (1.27e-2)" "unprognostic (6.69e-2)" "unprognostic (4.97e-2)" "unprognostic (3.33e-1)" "unprognostic (5.00e-2)" "unprognostic (3.75e-3)" "unprognostic (1.22e-1)" "unprognostic (1.33e-1)" "unprognostic (4.04e-1)" "unprognostic (1.17e-1)" "unprognostic (8.19e-2)" "unprognostic (1.57e-2)" "unprognostic (4.22e-2)" "unprognostic (1.54e-1)" "unprognostic (8.76e-2)" "unprognostic (1.46e-1)" TTC6 "C14orf25, NCRNA00291" ENSG00000139865 "Tetratricopeptide repeat domain 6" Q86TZ1 14 37595629-38041442 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 4.0;prostate: 6.1;testis: 4.6" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 407.8;Ependymal cells: 949.0;Mucous neck cells: 212.1;Prostatic club cells: 237.3;Prostatic glandular cells: 1854.6;Respiratory basal cells: 226.2" "Cell type enriched" "Detected in many" 6 "ependymal cell: 1114.0" "Group enriched" "Detected in many" 5 "Breast Invasive Carcinoma (TCGA): 10.3;Prostate Adenocarcinoma (TCGA): 20.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "prostate cancer: 11.3" "Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Testis - Early spermatids" "Not detected" "Not detected" "Region enriched" "Detected in some" 6 "midbrain: 8.4" HPA069293 Approved "Centrosome,Basal body" NA NA "Cluster 21: Testis - Mixed function" "Cluster 46: Brainstem - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" Centrosome "Basal body" "HPA069293: " "unprognostic (1.58e-3)" "unprognostic (4.74e-2)" "unprognostic (1.92e-2)" "unprognostic (5.86e-2)" "unprognostic (1.88e-1)" "unprognostic (3.33e-3)" "unprognostic (2.62e-1)" "unprognostic (4.82e-2)" "unprognostic (2.80e-1)" "unprognostic (1.39e-1)" "unprognostic (7.32e-2)" "unprognostic (1.35e-1)" "unprognostic (9.08e-2)" TTC7A "KIAA1140, TTC7" ENSG00000068724 "Tetratricopeptide repeat domain 7A" Q9ULT0 2 46915869-47076137 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 38.0" "Cell type enhanced" "Detected in many" "Late spermatids: 338.7;Microglia: 281.1" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 409.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA036781, HPA036782" Enhanced NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 8: Immune cells - Immune response" "Cluster 6: Leukemia - Signal transduction" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 2 "HPA036781: , HPA036782: " "unprognostic (2.73e-2)" "unprognostic (5.71e-2)" "unprognostic (1.45e-3)" "unprognostic (3.78e-2)" "unprognostic (5.33e-3)" "unprognostic (6.44e-2)" "unprognostic (1.01e-1)" "unprognostic (8.63e-2)" "unprognostic (1.34e-1)" "unprognostic (2.04e-1)" "potential prognostic favorable (2.49e-6)" "unprognostic (6.30e-2)" "unprognostic (7.84e-2)" "unprognostic (9.56e-2)" "unprognostic (4.70e-2)" "unprognostic (8.19e-2)" "unprognostic (9.43e-2)" "unprognostic (2.04e-2)" "unprognostic (7.36e-2)" "unprognostic (5.87e-3)" "unprognostic (2.05e-1)" "validated prognostic unfavorable (1.81e-4)" "validated prognostic unfavorable (7.20e-4)" "unprognostic (8.47e-2)" "unprognostic (4.93e-3)" "unprognostic (1.18e-1)" "unprognostic (4.75e-1)" "unprognostic (1.20e-1)" "unprognostic (1.38e-1)" "unprognostic (1.20e-2)" "unprognostic (3.98e-3)" TTC7B TTC7L1 ENSG00000165914 "Tetratricopeptide repeat domain 7B" Q86TV6 14 90524564-90816479 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 105.9" "Cell type enhanced" "Detected in many" "Retinal amacrine cells: 261.0;Retinal ganglion cells: 347.7;Syncytiotrophoblasts: 382.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "basophil: 5.6;eosinophil: 8.1" "Lineage enriched" "Detected in single" 9 "granulocytes: 8.1" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Prostate - Smooth muscle cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058363, HPA059577" Enhanced Supported "Plasma membrane" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 27: Cerebellum - Synaptic function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 10 "Plasma membrane" "HPA058363: , HPA059577: " "unprognostic (2.11e-1)" "unprognostic (3.64e-1)" "unprognostic (1.09e-2)" "unprognostic (7.62e-3)" "unprognostic (3.22e-2)" "unprognostic (9.26e-2)" "unprognostic (1.93e-1)" "unprognostic (2.01e-2)" "unprognostic (1.08e-3)" "unprognostic (1.34e-2)" "potential prognostic favorable (1.59e-7)" "unprognostic (1.05e-3)" "unprognostic (5.43e-2)" "unprognostic (1.31e-1)" "unprognostic (8.35e-2)" "unprognostic (2.87e-1)" "unprognostic (1.28e-3)" "unprognostic (1.09e-1)" "unprognostic (1.21e-1)" "unprognostic (1.75e-1)" "unprognostic (2.90e-3)" "unprognostic (3.72e-2)" "unprognostic (3.12e-2)" "unprognostic (1.58e-1)" "unprognostic (5.16e-2)" "unprognostic (3.64e-2)" "unprognostic (1.35e-1)" "unprognostic (2.79e-2)" "unprognostic (2.34e-1)" "unprognostic (1.11e-2)" "unprognostic (5.17e-2)" TTC8 "BBS8, RP51" ENSG00000165533 "Tetratricopeptide repeat domain 8" Q8TAM2 14 88824153-88881078 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Transport" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Intellectual disability, Obesity, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 191.5;Cone photoreceptor cells: 316.7;Ependymal cells: 269.6;Gonadotrophs: 200.5;Lactotrophs: 298.1;Rod photoreceptor cells: 322.4;Sertoli cells: 339.2;Somatotrophs: 200.7;Thyrotrophs: 259.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 13.7" "Lineage enriched" "Detected in many" 6 "granulocytes: 13.7" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skeletal muscle - Fibroblasts, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003310 Approved "Nucleoli fibrillar center,Basal body,Perinuclear theca,Flagellar centriole" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 79: Photoreceptor cells - Phototransduction" 16 "Nucleoli fibrillar center, Basal body" "Perinuclear theca, Flagellar centriole" "HPA003310: " "unprognostic (8.34e-2)" "unprognostic (5.43e-2)" "unprognostic (6.09e-2)" "unprognostic (3.79e-2)" "unprognostic (2.59e-2)" "unprognostic (1.81e-1)" "unprognostic (2.34e-1)" "unprognostic (3.10e-1)" "unprognostic (1.92e-1)" "unprognostic (6.76e-2)" "potential prognostic favorable (2.19e-4)" "unprognostic (5.52e-3)" "unprognostic (1.02e-2)" "unprognostic (3.78e-3)" "unprognostic (1.65e-2)" "unprognostic (1.55e-3)" "unprognostic (1.79e-1)" "unprognostic (3.51e-1)" "unprognostic (3.23e-3)" "unprognostic (9.90e-3)" "unprognostic (2.15e-1)" "unprognostic (8.27e-2)" "unprognostic (8.02e-2)" "unprognostic (1.71e-1)" "unprognostic (2.06e-1)" "unprognostic (9.26e-3)" "unprognostic (1.48e-1)" "unprognostic (5.71e-2)" "unprognostic (2.92e-1)" "unprognostic (2.16e-1)" "unprognostic (7.52e-2)" TTC9 "KIAA0227, TTC9A" ENSG00000133985 "Tetratricopeptide repeat domain 9" Q92623 14 70641916-70675366 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "esophagus: 60.0" "Cell type enriched" "Detected in many" 9 "Esophageal apical cells: 862.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Spleen - B-cells (Spleen), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA079473 Approved "Nuclear bodies" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" "Nuclear bodies" "HPA079473: " "unprognostic (1.02e-1)" "unprognostic (1.97e-3)" "unprognostic (9.60e-2)" "unprognostic (3.10e-1)" "unprognostic (2.91e-1)" "unprognostic (1.77e-1)" "unprognostic (4.56e-2)" "unprognostic (6.05e-2)" "unprognostic (4.62e-2)" "unprognostic (4.62e-1)" "potential prognostic favorable (3.56e-7)" "unprognostic (2.31e-3)" "unprognostic (1.34e-2)" "unprognostic (3.96e-2)" "unprognostic (2.45e-2)" "unprognostic (1.02e-2)" "unprognostic (2.35e-2)" "unprognostic (1.58e-1)" "unprognostic (1.32e-1)" "unprognostic (3.64e-2)" "unprognostic (1.35e-1)" "unprognostic (1.17e-2)" "unprognostic (5.05e-2)" "unprognostic (5.54e-1)" "unprognostic (2.19e-2)" "unprognostic (4.64e-2)" "unprognostic (2.41e-2)" "unprognostic (6.23e-2)" "unprognostic (2.21e-1)" "unprognostic (2.17e-3)" TTC9B FLJ30373 ENSG00000174521 "Tetratricopeptide repeat domain 9B" Q8N6N2 19 40216058-40218384 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 82 "brain: 174.4" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 70.7;Brain inhibitory neurons: 27.0;Early primary spermatocytes: 12.6;Oligodendrocyte progenitor cells: 41.8;Other brain neurons: 49.8;Retinal amacrine cells: 28.3;Retinal bipolar cells: 21.6" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in single" 27 "Glioblastoma Multiforme (TCGA): 16.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 20 "Neuroblastoma: 27.0" "Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042496 Approved Approved Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 98: Neurons - Neurotransmission & signaling" "Nucleoplasm, Mitochondria" Vesicles "HPA042496: " "unprognostic (4.99e-2)" "potential prognostic favorable (5.18e-4)" TTC9C MGC29649 ENSG00000162222 "Tetratricopeptide repeat domain 9C" Q8N5M4 11 62728069-62740293 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "Oocytes: 340.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055169 Approved Approved "Nucleoplasm,Primary cilium tip,Cytosol" NA Yes "Cluster 29: Non-specific - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 34: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 41: Oocytes - Oogenesis" 40 Nucleoplasm "Primary cilium tip, Cytosol" "HPA055169: " "unprognostic (3.44e-3)" "unprognostic (1.56e-1)" "unprognostic (2.90e-1)" "unprognostic (1.12e-3)" "unprognostic (6.15e-2)" "unprognostic (5.25e-2)" "unprognostic (1.78e-1)" "unprognostic (6.15e-2)" "unprognostic (3.56e-3)" "potential prognostic unfavorable (5.75e-6)" "potential prognostic favorable (6.96e-4)" "unprognostic (3.20e-1)" "unprognostic (2.93e-1)" "potential prognostic unfavorable (1.35e-4)" "unprognostic (1.17e-2)" "unprognostic (8.14e-3)" "potential prognostic unfavorable (5.55e-4)" "unprognostic (7.40e-2)" "unprognostic (1.66e-1)" "unprognostic (8.40e-2)" "unprognostic (1.21e-1)" "potential prognostic unfavorable (6.48e-4)" "unprognostic (2.97e-2)" "unprognostic (8.05e-3)" "unprognostic (4.27e-2)" "unprognostic (4.85e-2)" "unprognostic (1.82e-1)" "unprognostic (3.85e-2)" "unprognostic (6.11e-2)" "unprognostic (1.61e-1)" "unprognostic (1.81e-1)" TTF1 ENSG00000125482 "Transcription termination factor 1" Q15361 9 132375548-132406851 "Essential proteins, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation, Transcription termination" "DNA replication inhibitor, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051105, HPA054837" Supported Supported "Nucleoli fibrillar center" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 6: Leukemia - Signal transduction" "Cluster 7: Non-specific - Transcription" 30 "Nucleoli fibrillar center" "HPA051105: , HPA054837: " "unprognostic (1.43e-2)" "unprognostic (6.26e-3)" "unprognostic (2.62e-1)" "unprognostic (1.46e-1)" "unprognostic (8.74e-2)" "unprognostic (5.19e-3)" "unprognostic (1.57e-1)" "potential prognostic favorable (1.96e-5)" "unprognostic (1.06e-1)" "unprognostic (6.44e-2)" "validated prognostic favorable (2.39e-5)" "validated prognostic favorable (5.22e-4)" "unprognostic (2.85e-1)" "potential prognostic unfavorable (3.51e-4)" "unprognostic (3.40e-2)" "unprognostic (5.51e-2)" "potential prognostic unfavorable (2.14e-4)" "unprognostic (7.25e-2)" "unprognostic (3.12e-2)" "unprognostic (3.19e-1)" "unprognostic (6.78e-2)" "unprognostic (1.07e-1)" "unprognostic (9.60e-2)" "unprognostic (5.18e-2)" "unprognostic (6.89e-3)" "unprognostic (4.09e-2)" "unprognostic (2.26e-2)" "unprognostic (6.32e-2)" "unprognostic (1.49e-1)" "unprognostic (2.28e-1)" "unprognostic (1.39e-1)" TTF2 "HuF2, ZGRF6" ENSG00000116830 "Transcription termination factor 2" Q9UNY4 1 117060326-117107453 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, Transcription, Transcription regulation, Transcription termination" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Monocyte progenitors: 90.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA005776, HPA070762" Approved Supported Cytosol NA Yes "Cluster 33: Non-specific - ATP binding" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 11: White matter - Signal transduction" "Cluster 37: Non-specific - mRNA processing" "Cluster 27: Non-specific - Cell proliferation" 41 Cytosol "HPA005776: , HPA070762: " "unprognostic (2.65e-2)" "unprognostic (2.00e-1)" "unprognostic (2.25e-1)" "unprognostic (6.18e-2)" "unprognostic (1.37e-2)" "unprognostic (9.06e-2)" "unprognostic (2.15e-1)" "unprognostic (1.54e-1)" "unprognostic (4.20e-2)" "unprognostic (1.70e-3)" "unprognostic (4.22e-2)" "unprognostic (4.27e-2)" "unprognostic (1.54e-1)" "unprognostic (9.24e-3)" "unprognostic (2.07e-2)" "unprognostic (4.37e-3)" "unprognostic (5.03e-2)" "potential prognostic favorable (4.27e-4)" "unprognostic (1.30e-2)" "unprognostic (3.46e-1)" "unprognostic (9.17e-2)" "unprognostic (7.83e-2)" "unprognostic (1.22e-1)" "unprognostic (3.14e-2)" "unprognostic (5.53e-3)" "unprognostic (6.80e-2)" "unprognostic (1.42e-1)" "unprognostic (1.97e-2)" "unprognostic (2.58e-1)" "unprognostic (7.34e-2)" "unprognostic (7.21e-2)" TTI1 "KIAA0406, smg-10" ENSG00000101407 "TELO2 interacting protein 1" O43156 20 37983007-38033461 "Essential proteins, Predicted intracellular proteins" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034230, HPA068338" Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 9: Non-specific - Receptor signaling" "Cluster 62: Non-specific - Plasma proteins" "Cluster 7: Non-specific - Transcription" 51 Vesicles Nucleoplasm "CAB034230: , HPA068338: " "unprognostic (1.16e-1)" "unprognostic (7.39e-3)" "unprognostic (1.02e-2)" "unprognostic (1.90e-1)" "unprognostic (4.19e-1)" "unprognostic (2.25e-1)" "unprognostic (2.70e-2)" "unprognostic (8.90e-2)" "unprognostic (2.66e-3)" "unprognostic (2.01e-3)" "unprognostic (1.34e-1)" "unprognostic (3.43e-1)" "potential prognostic unfavorable (2.76e-7)" "unprognostic (1.96e-3)" "unprognostic (4.88e-2)" "potential prognostic unfavorable (7.50e-6)" "unprognostic (1.24e-2)" "unprognostic (3.52e-1)" "unprognostic (1.09e-1)" "unprognostic (3.47e-1)" "unprognostic (2.12e-1)" "potential prognostic unfavorable (4.27e-6)" "unprognostic (1.78e-1)" "unprognostic (1.71e-3)" "unprognostic (6.30e-3)" "unprognostic (1.23e-1)" "unprognostic (3.04e-1)" "unprognostic (8.46e-2)" "unprognostic (4.55e-2)" "unprognostic (2.40e-1)" TTI2 "C8orf41, FLJ23263" ENSG00000129696 "TELO2 interacting protein 2" Q6NXR4 8 33473386-33513185 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epicardial cells: 72.8;Late primary spermatocytes: 77.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023523, HPA029823" Approved Approved Nucleoplasm,Centrosome NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 40: Non-specific - Unknown function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 12 Centrosome Nucleoplasm "HPA023523: , HPA029823: " "unprognostic (1.50e-2)" "unprognostic (7.33e-2)" "unprognostic (5.21e-2)" "unprognostic (4.75e-3)" "potential prognostic unfavorable (9.70e-4)" "unprognostic (3.73e-2)" "potential prognostic favorable (1.83e-4)" "unprognostic (1.88e-2)" "unprognostic (2.11e-2)" "potential prognostic favorable (4.02e-6)" "unprognostic (8.15e-3)" "unprognostic (1.73e-1)" "potential prognostic unfavorable (4.08e-6)" "unprognostic (1.34e-1)" "unprognostic (7.34e-2)" "unprognostic (5.98e-2)" "unprognostic (1.96e-2)" "unprognostic (9.79e-2)" "unprognostic (8.80e-2)" "unprognostic (1.37e-1)" "unprognostic (2.89e-1)" "unprognostic (1.83e-2)" "unprognostic (8.09e-2)" "unprognostic (2.06e-2)" "unprognostic (4.86e-1)" "unprognostic (7.89e-2)" "unprognostic (1.07e-1)" "unprognostic (6.63e-2)" "unprognostic (9.69e-2)" TTK "CT96, MPH1, MPS1, MPS1L1" ENSG00000112742 "TTK protein kinase" P33981 6 80003887-80042527 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 23.9;lymphoid tissue: 43.4;testis: 32.1" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 45.7;Early primary spermatocytes: 51.3;Erythrocyte progenitors: 54.0;Late primary spermatocytes: 228.8;Megakaryocyte progenitors: 55.4;Megakaryocytes: 661.4;Monocyte progenitors: 79.1;Neutrophil progenitors: 46.0;Oocytes: 119.7" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 1.2" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB010166, CAB013229, HPA058657" Enhanced Approved Nucleoli,Cytosol NA Yes "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 28: Non-specific - Nuclear processes" "Cluster 27: Non-specific - Cell proliferation" 17 Cytosol Nucleoli "CAB010166: , CAB013229: , HPA058657: " "unprognostic (2.30e-2)" "unprognostic (3.57e-2)" "unprognostic (1.17e-1)" "unprognostic (8.43e-2)" "unprognostic (8.10e-2)" "unprognostic (1.89e-1)" "unprognostic (1.38e-1)" "unprognostic (3.28e-3)" "unprognostic (5.99e-2)" "potential prognostic unfavorable (4.12e-5)" "validated prognostic unfavorable (4.97e-8)" "validated prognostic unfavorable (1.96e-5)" "validated prognostic unfavorable (5.17e-11)" "validated prognostic unfavorable (3.11e-7)" "potential prognostic unfavorable (9.06e-5)" "unprognostic (7.85e-3)" "unprognostic (1.54e-2)" "unprognostic (4.66e-2)" "unprognostic (9.08e-2)" "unprognostic (2.39e-1)" "validated prognostic unfavorable (8.10e-5)" "validated prognostic unfavorable (6.11e-4)" "unprognostic (1.87e-1)" "unprognostic (7.61e-3)" "unprognostic (3.68e-2)" "unprognostic (1.77e-1)" "unprognostic (1.29e-1)" "unprognostic (2.31e-1)" "potential prognostic unfavorable (5.53e-4)" TTL MGC46235 ENSG00000114999 "Tubulin tyrosine ligase" Q8NG68 2 112482156-112541739 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 108.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066819 Approved Nucleoplasm,Vesicles NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 3 Vesicles Nucleoplasm "HPA066819: " "unprognostic (2.81e-1)" "unprognostic (2.02e-1)" "unprognostic (8.62e-3)" "unprognostic (1.19e-1)" "unprognostic (2.39e-1)" "unprognostic (7.21e-2)" "unprognostic (5.36e-1)" "unprognostic (3.12e-2)" "unprognostic (2.26e-1)" "unprognostic (1.57e-1)" "unprognostic (4.39e-2)" "unprognostic (5.49e-2)" "unprognostic (1.36e-1)" "unprognostic (1.12e-1)" "unprognostic (1.94e-1)" "unprognostic (2.00e-1)" "unprognostic (1.01e-2)" "unprognostic (1.56e-3)" "unprognostic (2.87e-1)" "unprognostic (3.13e-1)" "unprognostic (2.58e-1)" "unprognostic (1.91e-1)" TTLL1 "C22orf7, PGs3, TPGS3" ENSG00000100271 "TTL family tubulin polyglutamylase complex subunit L1" O95922 22 43039516-43089419 "Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 50.2;Early spermatids: 125.7;Undifferentiated spermatogonia: 67.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Kidney - Fibroblasts, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048392 Approved NA No "Cluster 5: Non-specific - Cell proliferation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 14: Neurons - Synaptic function" "Cluster 66: Non-specific - Mitochondria" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 1 "HPA048392: " "unprognostic (7.58e-2)" "unprognostic (1.02e-1)" "unprognostic (1.75e-2)" "unprognostic (3.42e-3)" "unprognostic (1.33e-2)" "unprognostic (3.32e-1)" "unprognostic (4.27e-2)" "unprognostic (2.24e-2)" "unprognostic (6.55e-3)" "unprognostic (2.17e-1)" "unprognostic (2.26e-3)" "unprognostic (5.17e-2)" "unprognostic (8.12e-3)" "potential prognostic unfavorable (2.79e-4)" "unprognostic (4.04e-2)" "unprognostic (7.16e-2)" "unprognostic (2.22e-1)" "unprognostic (1.74e-1)" "unprognostic (1.30e-2)" "unprognostic (1.39e-1)" "unprognostic (9.50e-3)" "unprognostic (5.73e-2)" "unprognostic (1.81e-1)" "unprognostic (3.01e-1)" "unprognostic (6.71e-2)" "unprognostic (6.64e-2)" "unprognostic (7.48e-2)" "unprognostic (1.56e-1)" "unprognostic (1.08e-1)" "unprognostic (7.01e-2)" "unprognostic (7.34e-2)" TTLL10 "FLJ36119, TTLL5" ENSG00000162571 "Tubulin tyrosine ligase like 10" Q6ZVT0 1 1173880-1197936 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "fallopian tube: 10.1;testis: 39.8" "Cell type enriched" "Detected in many" 4 "Late spermatids: 1302.6" "Group enriched" "Detected in some" 13 "choroid plexus epithelial cell: 23.9;ependymal cell: 41.7" "Cancer enhanced" "Detected in some" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 2.7;Uterine Corpus Endometrial Carcinoma (TCGA): 2.4" "Region enhanced" "Detected in many" "choroid plexus: 28.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Lung - Respiratory ciliated cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA042712 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" 10 Cytosol "Plasma membrane" "HPA042712: " "unprognostic (4.96e-2)" "unprognostic (8.83e-3)" "unprognostic (6.94e-3)" "potential prognostic favorable (7.02e-5)" "unprognostic (2.06e-1)" "unprognostic (3.69e-2)" "unprognostic (1.93e-1)" "unprognostic (2.13e-1)" "unprognostic (4.00e-2)" TTLL11 "bA244O19.1, C9orf148, C9orf20, TTLL11-IT1" ENSG00000175764 "Tubulin tyrosine ligase like 11" Q8NHH1 9 121815674-122093606 "Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 27.8" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 169.0;Choroid plexus epithelial cells: 148.7;Myonuclei: 293.0;Oligodendrocytes: 312.6" "Cell type enhanced" "Detected in all" "oligodendrocyte: 438.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021828 Approved NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 53: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 80: Oligodendrocytes - Myelination" "HPA021828: " "unprognostic (6.47e-2)" "unprognostic (1.03e-1)" "potential prognostic favorable (5.56e-5)" "unprognostic (5.60e-2)" "unprognostic (1.25e-1)" "unprognostic (1.44e-2)" "unprognostic (2.65e-1)" "unprognostic (7.06e-3)" "unprognostic (2.98e-1)" "unprognostic (1.36e-1)" "validated prognostic favorable (9.77e-8)" "validated prognostic favorable (2.24e-4)" "unprognostic (5.00e-3)" "unprognostic (4.44e-3)" "unprognostic (4.27e-1)" "potential prognostic favorable (6.49e-4)" "unprognostic (1.60e-2)" "unprognostic (1.77e-1)" "unprognostic (1.16e-1)" "unprognostic (6.17e-2)" "unprognostic (4.52e-2)" "unprognostic (2.58e-2)" "unprognostic (3.15e-1)" "unprognostic (1.24e-1)" "unprognostic (1.73e-1)" "unprognostic (1.09e-1)" "unprognostic (2.62e-1)" "unprognostic (1.32e-1)" "unprognostic (1.59e-1)" "unprognostic (8.56e-2)" "unprognostic (4.02e-1)" TTLL12 KIAA0153 ENSG00000100304 "Tubulin tyrosine ligase like 12" Q14166 22 43166622-43187134 "Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 98.6" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 293.8;Esophageal basal cells: 96.5;Esophageal suprabasal cells: 135.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003054, CAB046029" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 86000 "Cluster 30: Non-specific - DNA binding" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 24: Neurons - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 85: Squamous epithelial cells - Keratinization" 28 Cytosol "Nucleoplasm, Plasma membrane" "CAB046029: , HPA003054: " "unprognostic (5.43e-2)" "unprognostic (2.04e-2)" "unprognostic (9.60e-2)" "unprognostic (4.79e-2)" "unprognostic (1.35e-1)" "unprognostic (2.59e-1)" "unprognostic (1.29e-1)" "unprognostic (5.73e-2)" "unprognostic (1.60e-1)" "unprognostic (1.72e-1)" "unprognostic (1.49e-3)" "unprognostic (6.24e-2)" "unprognostic (1.40e-1)" "potential prognostic unfavorable (1.29e-4)" "unprognostic (8.42e-3)" "validated prognostic unfavorable (1.26e-4)" "validated prognostic unfavorable (5.74e-5)" "unprognostic (1.30e-1)" "unprognostic (8.16e-3)" "unprognostic (4.43e-2)" "unprognostic (8.84e-2)" "unprognostic (2.23e-2)" "unprognostic (2.18e-1)" "unprognostic (3.92e-1)" "unprognostic (1.40e-2)" "unprognostic (1.63e-3)" "unprognostic (2.35e-1)" "unprognostic (6.09e-3)" "unprognostic (2.42e-1)" "unprognostic (1.89e-2)" "unprognostic (1.02e-1)" TTLL13 "FLJ46079, MGC33417, TTLL13P" ENSG00000213471 "Tubulin tyrosine ligase like 13" A6NNM8 15 90249530-90265482 "Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 47 "testis: 7.6" "Group enriched" "Detected in some" 4 "Early spermatids: 1.7;Late spermatids: 5.2" "Low cell type specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA040133, HPA041305" Enhanced Approved "Plasma membrane,Basal body,Cytosol" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" "Plasma membrane, Cytosol" "Basal body" "HPA040133: , HPA041305: " TTLL2 "C6orf104, dJ366N23.3, NYD-TSPG" ENSG00000120440 "Tubulin tyrosine ligase like 2" Q9BWV7 6 167325071-167359503 "Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 14.3" "Group enriched" "Detected in some" 35 "Early spermatids: 575.7;Late spermatids: 334.5" "Cell type enhanced" "Detected in some" "oligodendrocyte precursor cell: 2.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Prostate - Prostate glandular cells, Testis - Late spermatids" "Not detected" "Not detected" HPA027985 Approved "Nuclear membrane,Nucleoli" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 35: RS4;11 - Unknown function" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 1 "Nuclear membrane, Nucleoli" "HPA027985: " "unprognostic (1.46e-2)" TTLL3 "DKFZP434B103, HOTTL" ENSG00000214021 "Tubulin tyrosine ligase like 3" Q9Y4R7 3 9808086-9855138 "Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 78.6;Bergmann glia: 55.4;Cardiomyocytes: 74.6;Choroid plexus epithelial cells: 75.8;Ependymal cells: 121.9;Microglia: 52.9;Oligodendrocyte progenitor cells: 38.6;Oligodendrocytes: 37.0;Other brain neurons: 38.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Colon - Enteric glia cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051413 Approved NA NA "Cluster 32: Basophils - Transcription" "Cluster 75: Ovary - Mixed function" "Cluster 46: Brainstem - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 22: Non-specific - Basic cellular functions" "HPA051413: " "unprognostic (8.24e-3)" "unprognostic (2.37e-1)" "unprognostic (1.93e-2)" "unprognostic (1.30e-2)" "unprognostic (5.25e-3)" "unprognostic (1.45e-2)" "unprognostic (1.40e-1)" "unprognostic (1.13e-1)" "unprognostic (5.49e-2)" "unprognostic (4.63e-2)" "potential prognostic unfavorable (3.24e-7)" "unprognostic (2.74e-2)" "unprognostic (6.22e-3)" "unprognostic (1.29e-1)" "unprognostic (1.99e-2)" "unprognostic (3.43e-2)" "unprognostic (1.58e-1)" "unprognostic (1.92e-1)" "unprognostic (3.11e-1)" "unprognostic (8.32e-2)" "unprognostic (2.50e-1)" "potential prognostic favorable (6.11e-4)" "unprognostic (8.49e-3)" "unprognostic (1.87e-1)" "unprognostic (9.56e-3)" "unprognostic (1.29e-3)" "unprognostic (8.91e-2)" "unprognostic (2.63e-2)" "unprognostic (1.38e-1)" "unprognostic (1.93e-1)" "unprognostic (1.03e-1)" TTLL4 KIAA0173 ENSG00000135912 "Tubulin tyrosine ligase like 4" Q14679 2 218710835-218755416 "Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 50.5;Bergmann glia: 64.8;Choroid plexus epithelial cells: 51.8;Early spermatids: 55.8;Müller glia: 91.0;Retinal pigment epithelial cells: 123.6" "Cell type enhanced" "Detected in all" "Bergmann glia: 63.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027091, HPA050252" Approved Uncertain Mitochondria NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" 5 Mitochondria "HPA027091: , HPA050252: " "unprognostic (1.30e-1)" "unprognostic (2.85e-2)" "potential prognostic favorable (1.77e-4)" "unprognostic (1.36e-2)" "unprognostic (8.46e-2)" "unprognostic (1.05e-1)" "unprognostic (4.94e-1)" "unprognostic (2.21e-1)" "unprognostic (2.01e-2)" "potential prognostic unfavorable (2.53e-5)" "unprognostic (7.22e-2)" "unprognostic (4.09e-1)" "unprognostic (1.24e-2)" "validated prognostic unfavorable (2.85e-5)" "validated prognostic unfavorable (9.09e-4)" "unprognostic (1.05e-2)" "unprognostic (2.03e-3)" "unprognostic (3.22e-2)" "unprognostic (8.80e-2)" "unprognostic (1.63e-1)" "potential prognostic favorable (7.13e-4)" "unprognostic (9.99e-2)" "potential prognostic unfavorable (6.06e-4)" "unprognostic (4.17e-2)" "unprognostic (3.51e-2)" "unprognostic (2.99e-1)" "unprognostic (2.22e-2)" "unprognostic (1.55e-1)" "unprognostic (3.98e-1)" "unprognostic (4.59e-1)" "unprognostic (6.52e-2)" TTLL5 "KIAA0998, STAMP" ENSG00000119685 "Tubulin tyrosine ligase like 5" Q6EMB2 14 75633625-75955079 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Transcription Ligase "Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 53.7" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 388.0;Cone photoreceptor cells: 511.3;Endometrial ciliated cells: 426.8;Ependymal cells: 491.2;Respiratory ciliated cells: 352.9;Rod photoreceptor cells: 477.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Spleen - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" HPA032128 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 47: Testis - Mixed function" "Cluster 30: White matter - Myelination" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 79: Photoreceptor cells - Phototransduction" 4 "Plasma membrane, Cytosol" "HPA032128: " "unprognostic (1.38e-2)" "unprognostic (3.43e-1)" "unprognostic (3.66e-1)" "unprognostic (6.76e-3)" "unprognostic (2.94e-1)" "unprognostic (1.69e-1)" "unprognostic (3.20e-2)" "unprognostic (2.84e-2)" "unprognostic (1.14e-1)" "unprognostic (3.31e-3)" "unprognostic (1.12e-3)" "unprognostic (1.21e-2)" "unprognostic (6.22e-2)" "potential prognostic unfavorable (1.04e-4)" "unprognostic (1.80e-1)" "unprognostic (1.29e-1)" "unprognostic (6.14e-3)" "unprognostic (6.64e-2)" "unprognostic (3.50e-1)" "unprognostic (3.81e-1)" "unprognostic (1.38e-2)" "unprognostic (3.85e-3)" "unprognostic (1.90e-2)" "unprognostic (1.12e-2)" "unprognostic (8.48e-2)" "unprognostic (2.70e-1)" "unprognostic (5.64e-3)" "unprognostic (2.34e-1)" "unprognostic (2.20e-1)" "unprognostic (7.92e-2)" "unprognostic (1.98e-1)" TTLL6 FLJ35808 ENSG00000170703 "Tubulin tyrosine ligase like 6" Q8N841 17 48762234-48817229 "Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 4.6;testis: 18.2" "Cell type enriched" "Detected in many" 4 "Late spermatids: 325.4" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 26.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 2.3" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Pituitary gland - Corticotropes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA052397 Enhanced Supported "Microtubules,Primary cilium,Basal body,Flagellar centriole,Mid piece,Principal piece,End piece" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" "Microtubules, Primary cilium, Basal body, Flagellar centriole" "Mid piece, Principal piece, End piece" "HPA052397: " "unprognostic (4.29e-1)" "unprognostic (1.71e-2)" "unprognostic (2.25e-1)" "unprognostic (1.47e-1)" "unprognostic (8.88e-2)" "unprognostic (2.47e-2)" "potential prognostic unfavorable (9.13e-5)" "potential prognostic favorable (4.12e-4)" "unprognostic (2.64e-1)" "unprognostic (1.08e-1)" "unprognostic (2.10e-1)" "unprognostic (4.96e-1)" TTLL7 FLJ23033 ENSG00000137941 "Tubulin tyrosine ligase like 7" Q6ZT98 1 83865024-83999150 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein, Ligase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 17.3;brain: 26.7" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 1906.9" "Cell type enhanced" "Detected in all" "oligodendrocyte: 2322.4" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 3.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052249 Approved NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 11: White matter - Signal transduction" "Cluster 37: Non-specific - mRNA processing" "Cluster 80: Oligodendrocytes - Myelination" 1 "HPA052249: " "unprognostic (3.32e-2)" "unprognostic (3.41e-2)" "unprognostic (9.14e-2)" "unprognostic (2.11e-2)" "potential prognostic favorable (1.09e-7)" "unprognostic (1.27e-2)" "unprognostic (4.29e-2)" "unprognostic (2.64e-1)" "unprognostic (3.27e-2)" "unprognostic (1.90e-1)" "unprognostic (1.17e-1)" "unprognostic (2.42e-2)" "unprognostic (3.36e-1)" TTLL8 ENSG00000138892 "Tubulin tyrosine ligase like 8" 22 50018575-50058298 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 40 "testis: 3.9" "Cell type enhanced" "Detected in some" "Early spermatids: 52.8;Endometrial glandular cells: 15.1;Endometrial luminal cells: 23.6;Endometrial secretory cells: 27.2;Epicardial cells: 6.8;Late primary spermatocytes: 18.3;Late spermatids: 24.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA016882 Uncertain NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" "HPA016882: " TTLL9 "C20orf125, dJ310O13.1" ENSG00000131044 "Tubulin tyrosine ligase like 9" Q3SXZ7 20 31870634-31945000 "Cancer-related genes, Predicted intracellular proteins" Ligase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "choroid plexus: 14.6" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 315.6;Endometrial ciliated cells: 87.1;Ependymal cells: 319.0;Epididymal efferent duct ciliated cells: 55.0;Fallopian tube ciliated cells: 105.5;Late primary spermatocytes: 74.5;Late spermatids: 146.6;Respiratory ciliated cells: 211.4" "Group enriched" "Detected in many" 5 "choroid plexus epithelial cell: 246.0;ependymal cell: 347.9" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 1.8;Uterine Corpus Endometrial Carcinoma (TCGA): 1.4" "Region enhanced" "Detected in all" "choroid plexus: 22.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Breast glandular cells, Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA041772, HPA055676" Uncertain Approved "Nucleoplasm,Microtubules,Mitotic spindle,Primary cilium,Basal body,Mid piece,Principal piece,End piece" Yes NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 3: Choroid plexus - Cilium" "Cluster 11: Neuronal - Sensory perception" "Cluster 34: Ciliated cells - Cilia assembly & function" "Microtubules, Mid piece, Principal piece, End piece" "Nucleoplasm, Mitotic spindle, Primary cilium, Basal body" "HPA041772: , HPA055676: " "unprognostic (5.44e-1)" "unprognostic (2.30e-1)" "unprognostic (1.72e-1)" "unprognostic (1.82e-3)" "unprognostic (1.86e-1)" TTN "CMD1G, CMH9, CMPD4, FLJ32040, LGMD2J, MYLK5, TMD" ENSG00000155657 Titin Q8WZ42 2 178525989-178830802 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cardiomyopathy, Disease variant, Limb-girdle muscular dystrophy, Myofibrillar myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 151.7;skeletal muscle: 861.9;tongue: 345.1" "Group enriched" "Detected in many" 34 "Cardiomyocytes: 24623.7;Myonuclei: 35695.3;Thymic myoid cells: 20489.6" "Cell type enhanced" "Detected in all" "astrocyte: 349.3" "Cancer enriched" "Detected in single" 4 "Head and Neck Squamous Cell Carcinoma (TCGA): 3.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Sarcoma: 3.4" "Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2, Testis - Late spermatids" "Not detected" "Not detected" "HPA007042, CAB022682, HPA030048" Enhanced NA NA 4100000 "Cluster 24: Non-specific - Transcription" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 55: Myocytes - Oxidative muscle function" 51 "CAB022682: , HPA007042: , HPA030048: " "unprognostic (2.86e-3)" "unprognostic (3.35e-3)" "unprognostic (4.48e-2)" "unprognostic (1.44e-2)" "unprognostic (4.94e-2)" "unprognostic (5.30e-3)" "unprognostic (8.61e-3)" TTPA AVED ENSG00000137561 "Alpha tocopherol transfer protein" P49638 8 63048553-63086053 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 38 "liver: 154.2" "Cell type enhanced" "Detected in many" "Adipocytes: 59.5;Astrocytes: 111.4;Bergmann glia: 137.3;Cholangiocytes: 29.5;Cytotrophoblasts: 43.2;Hepatocytes: 288.9" "Group enriched" "Detected in many" 5 "astrocyte: 129.0;Bergmann glia: 154.2" "Cancer enriched" "Detected in some" 7 "Liver Hepatocellular Carcinoma (TCGA): 25.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Adrenocortical cancer: 3.0" "Adipose subcutaneous - Adipocytes (Subcutaneous), Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 5000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 19: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 28: Astrocytes - Homeostasis & neuron support" 36 "unprognostic (3.81e-2)" "unprognostic (8.39e-2)" "unprognostic (3.90e-3)" "unprognostic (3.10e-2)" "unprognostic (2.88e-2)" "unprognostic (4.90e-3)" "unprognostic (6.80e-3)" "unprognostic (9.19e-2)" "unprognostic (4.11e-2)" TTPAL "C20orf121, dJ179M20.3" ENSG00000124120 "Alpha tocopherol transfer protein like" Q9BTX7 20 44475874-44494603 "Plasma proteins, Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 27.4" "Cell type enhanced" "Detected in many" "Epicardial cells: 68.2;Hepatocytes: 74.0;Neutrophils: 114.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Macrophages, Prostate - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046957, HPA066532" Uncertain Approved "Golgi apparatus,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 1: Neurons - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 48: Neutrophils - Phagocytosis & degranulation" "Golgi apparatus, Cytosol" "HPA046957: , HPA066532: " "unprognostic (5.00e-2)" "unprognostic (7.70e-2)" "unprognostic (2.05e-1)" "potential prognostic unfavorable (2.65e-4)" "unprognostic (9.49e-2)" "unprognostic (1.13e-1)" "unprognostic (4.51e-1)" "unprognostic (1.08e-1)" "unprognostic (6.43e-3)" "unprognostic (2.97e-2)" "unprognostic (1.67e-1)" "potential prognostic unfavorable (1.39e-4)" "unprognostic (1.16e-1)" "unprognostic (1.90e-1)" "unprognostic (2.20e-2)" "unprognostic (1.26e-2)" "unprognostic (3.12e-2)" "unprognostic (5.17e-3)" "unprognostic (2.83e-1)" "unprognostic (4.55e-2)" "unprognostic (1.05e-3)" "unprognostic (1.28e-1)" "unprognostic (2.80e-3)" "unprognostic (1.62e-1)" "unprognostic (1.09e-2)" "unprognostic (9.02e-2)" "unprognostic (3.63e-2)" "unprognostic (9.80e-2)" "unprognostic (4.02e-1)" "unprognostic (2.36e-2)" "unprognostic (1.47e-1)" TTR "CTS, CTS1, HsT2651, PALB" ENSG00000118271 Transthyretin P02766 18 31557009-31598833 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Transport "Hormone, Thyroid hormone" "Amyloidosis, Cancer-related genes, Disease variant, FDA approved drug targets, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 34 "choroid plexus: 672504.5" "Group enriched" "Detected in many" 6 "Hepatocytes: 31024.8;Pancreatic islet cells: 53364.3;Retinal pigment epithelial cells: 61787.5" "Cell type enriched" "Detected in many" 8 "choroid plexus epithelial cell: 40087.7" "Group enriched" "Detected in many" 21 "Liver Hepatocellular Carcinoma (TCGA): 5122.1;Pancreatic Adenocarcinoma (TCGA): 4235.1" "Region enriched" "Detected in all" 82 "choroid plexus: 302089.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "Gastric cancer: 130.8;liver cancer: 177.5" "Liver - Hepatocytes, Pancreas - Alpha cells, Pituitary gland - Thyrotropes, Testis - Early spermatids, Testis - Late spermatids" "Group enriched" "Detected in all" 5 "basal ganglia: 1538.8;hippocampal formation: 4894.4;pons and medulla: 5760.6;thalamus: 3403.0" "Region enhanced" "Detected in all" "medulla oblongata: 1291.2" "CAB002517, HPA002550, CAB062567, CAB073406" Supported Approved "Golgi apparatus" "Secreted to blood" Hormone NA NA 345000000000 69000000000 "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 82 "Golgi apparatus" "CAB002517: , CAB062567: , CAB073406: , HPA002550: " "unprognostic (1.74e-2)" "unprognostic (2.14e-3)" "unprognostic (2.36e-1)" "unprognostic (7.56e-2)" "unprognostic (9.13e-3)" "unprognostic (3.33e-1)" "unprognostic (2.88e-2)" "unprognostic (1.76e-1)" "unprognostic (2.00e-1)" "unprognostic (3.81e-2)" "unprognostic (9.90e-2)" "unprognostic (9.78e-3)" "unprognostic (1.09e-3)" "unprognostic (8.07e-2)" "unprognostic (3.57e-2)" "unprognostic (1.64e-1)" "unprognostic (8.01e-3)" "unprognostic (5.15e-2)" "unprognostic (6.35e-2)" "unprognostic (2.62e-1)" "unprognostic (2.02e-3)" "unprognostic (8.28e-2)" "unprognostic (3.94e-2)" "unprognostic (1.05e-1)" "unprognostic (5.14e-2)" TTYH1 ENSG00000167614 "Tweety family member 1" Q9H313 19 54415219-54436904 "Predicted membrane proteins, Transporters" "Cell adhesion, Ion transport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 418.6" "Cell type enhanced" "Detected in some" "Astrocytes: 426.4;Bergmann glia: 398.3;Ependymal cells: 94.5;Oligodendrocyte progenitor cells: 108.9;Oligodendrocytes: 161.6" "Cell type enhanced" "Detected in all" "astrocyte: 419.0;Bergmann glia: 451.6" "Cancer enriched" "Detected in some" 11 "Glioblastoma Multiforme (TCGA): 48.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Enteric glia cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Skin - Eccrine sweat gland cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005725, HPA023617, HPA050655" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 28: Astrocytes - Homeostasis & neuron support" 3 "Nucleoplasm, Plasma membrane" "HPA005725: , HPA023617: , HPA050655: " "unprognostic (1.79e-2)" "unprognostic (4.57e-1)" "unprognostic (1.43e-2)" "unprognostic (3.16e-2)" "unprognostic (4.05e-2)" "unprognostic (1.23e-1)" "unprognostic (4.53e-1)" "unprognostic (2.14e-2)" "unprognostic (3.13e-2)" "potential prognostic unfavorable (7.07e-4)" "unprognostic (1.24e-1)" "unprognostic (1.69e-1)" TTYH2 C17orf29 ENSG00000141540 "Tweety family member 2" Q9BSA4 17 74213571-74262020 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "brain: 113.1" "Cell type enhanced" "Detected in many" "Astrocytes: 76.1;Bergmann glia: 49.7;cDC: 123.1;Macrophages: 50.0;monocytes: 44.5;Oligodendrocytes: 302.4;Retinal bipolar cells: 111.2;Retinal pigment epithelial cells: 55.4;Sertoli cells: 51.3" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 129.4;oligodendrocyte: 359.7" "Group enriched" "Detected in all" 6 "Glioblastoma Multiforme (TCGA): 47.9;Skin Cutaneous Melanoma (TCGA): 58.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 13.3;intermediate monocyte: 22.3;myeloid DC: 14.6;non-classical monocyte: 28.8;plasmacytoid DC: 18.3" "Group enriched" "Detected in many" 5 "dendritic cells: 18.3;monocytes: 28.8" "Cancer enhanced" "Detected in many" "skin cancer: 31.1" "Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 82: Dendritic cells - Antigen presentation" 5 "unprognostic (2.08e-1)" "unprognostic (1.27e-1)" "unprognostic (9.37e-3)" "unprognostic (9.65e-2)" "potential prognostic unfavorable (6.57e-5)" "unprognostic (8.95e-3)" "unprognostic (2.60e-1)" "unprognostic (5.28e-3)" "unprognostic (4.19e-1)" "unprognostic (1.79e-3)" "unprognostic (3.73e-2)" "unprognostic (8.50e-3)" "unprognostic (6.47e-3)" "unprognostic (3.75e-2)" "unprognostic (2.10e-1)" "unprognostic (1.56e-2)" "unprognostic (2.19e-1)" "unprognostic (3.39e-1)" "unprognostic (4.07e-2)" "unprognostic (2.77e-1)" "unprognostic (1.93e-1)" "unprognostic (1.53e-2)" "unprognostic (5.10e-2)" "unprognostic (5.11e-2)" "unprognostic (3.89e-1)" "unprognostic (6.56e-3)" "unprognostic (1.43e-1)" "unprognostic (6.99e-3)" "unprognostic (5.07e-2)" "unprognostic (2.32e-3)" "unprognostic (4.80e-3)" TTYH3 KIAA1691 ENSG00000136295 "Tweety family member 3" Q9C0H2 7 2631961-2664802 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 92.1" "Cell type enhanced" "Detected in many" "Bergmann glia: 73.6;Hofbauer cells: 283.9;Kupffer cells: 172.2;Macrophages: 139.7;monocytes: 109.5;Platelets: 101.2;Proximal tubule cells: 121.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 9.9;non-classical monocyte: 8.4" "Lineage enriched" "Detected in many" 5 "monocytes: 9.9" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Minor Salivary Gland - Minor salivary glandular cells, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053520 Uncertain NA NA 26000 "Cluster 40: Monocytes - Innate immune response" "Cluster 64: Non-specific - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 2 "HPA053520: " "unprognostic (4.66e-1)" "unprognostic (3.25e-2)" "unprognostic (7.23e-2)" "unprognostic (2.79e-3)" "unprognostic (8.34e-2)" "unprognostic (1.99e-1)" "unprognostic (2.88e-2)" "unprognostic (2.84e-3)" "unprognostic (1.23e-1)" "unprognostic (3.67e-2)" "unprognostic (1.20e-2)" "unprognostic (1.57e-1)" "unprognostic (4.29e-2)" "potential prognostic unfavorable (4.71e-6)" "unprognostic (1.62e-1)" "unprognostic (5.70e-2)" "unprognostic (1.20e-2)" "unprognostic (2.29e-1)" "unprognostic (1.44e-1)" "unprognostic (5.74e-3)" "unprognostic (3.25e-2)" "unprognostic (1.73e-2)" "unprognostic (2.09e-2)" "unprognostic (2.75e-2)" "unprognostic (9.90e-3)" "unprognostic (5.73e-2)" "unprognostic (2.36e-1)" "unprognostic (1.75e-1)" "unprognostic (2.04e-1)" "unprognostic (1.13e-1)" "unprognostic (5.63e-2)" TUB rd5 ENSG00000166402 "TUB bipartite transcription factor" P50607 11 8019244-8106243 "Disease related genes, Predicted intracellular proteins" "Phagocytosis, Sensory transduction" Obesity "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 76.5" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 95.7;Cone photoreceptor cells: 149.0;Lactotrophs: 116.6;Rod photoreceptor cells: 309.8;Somatotrophs: 218.8;Thyrotrophs: 163.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 50.5" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Cardiomyocytes, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017997, HPA049019" Uncertain Approved "Vesicles,Plasma membrane,Centriolar satellite,Basal body" "Intracellular and membrane" Other NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 79: Photoreceptor cells - Phototransduction" 1 "Centriolar satellite, Basal body" "Vesicles, Plasma membrane" "HPA017997: , HPA049019: " "unprognostic (1.16e-1)" "unprognostic (1.36e-1)" "unprognostic (1.17e-3)" "unprognostic (1.50e-1)" "unprognostic (9.18e-2)" "unprognostic (1.34e-1)" "unprognostic (7.52e-3)" "unprognostic (2.90e-2)" "unprognostic (3.79e-2)" "potential prognostic favorable (3.22e-4)" "unprognostic (2.69e-2)" "unprognostic (1.40e-3)" "unprognostic (1.04e-3)" "unprognostic (1.12e-1)" "unprognostic (2.93e-1)" "unprognostic (1.58e-1)" "unprognostic (1.88e-3)" "unprognostic (9.00e-3)" "unprognostic (2.32e-2)" "potential prognostic favorable (6.13e-4)" "unprognostic (9.70e-2)" "unprognostic (3.05e-1)" "unprognostic (1.85e-2)" "unprognostic (3.00e-2)" "unprognostic (1.06e-3)" "unprognostic (2.10e-1)" "unprognostic (1.29e-1)" "unprognostic (1.04e-1)" TUBA1A "B-ALPHA-1, FLJ25113, TUBA3" ENSG00000167552 "Tubulin alpha 1a" Q71U36 12 49184686-49189080 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Transporters" Hydrolase "Cancer-related genes, Disease variant, FDA approved drug targets, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 2689.9" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 657.9;Decidual stromal cells: 1712.1;Fallopian tube ciliated cells: 1193.1;Hofbauer cells: 683.1;Mast cells: 745.4;Müller glia: 713.0;Neutrophils: 742.8;Respiratory ciliated cells: 1523.0;Schwann cells: 843.6;Smooth muscle cells: 701.4" "Cell type enhanced" "Detected in all" "oligodendrocyte: 786.8" "Cancer enriched" "Detected in all" 10 "Glioblastoma Multiforme (TCGA): 3672.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1667.7" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Neuroblastoma: 1234.9" "Adipose subcutaneous - Adipose progenitor cells, Colon - Smooth muscle cells, Kidney - Macrophages, Prostate - Smooth muscle cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008686, HPA039247, HPA043684, HPA063394" Enhanced Enhanced "Microtubules,Primary cilium" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 232 Microtubules "Primary cilium" "CAB008686: , HPA039247: , HPA043684: , HPA063394: " "unprognostic (1.72e-1)" "unprognostic (2.85e-2)" "unprognostic (1.92e-1)" "unprognostic (8.03e-2)" "unprognostic (1.20e-1)" "unprognostic (1.90e-3)" "unprognostic (1.29e-1)" "unprognostic (4.65e-1)" "unprognostic (1.78e-2)" "unprognostic (1.19e-2)" "unprognostic (1.90e-2)" "unprognostic (2.96e-3)" "unprognostic (2.06e-1)" "unprognostic (2.48e-2)" "unprognostic (9.56e-2)" "unprognostic (4.82e-2)" "unprognostic (5.32e-1)" "unprognostic (1.39e-2)" "unprognostic (1.55e-1)" "unprognostic (1.98e-1)" "unprognostic (2.23e-1)" "unprognostic (1.63e-3)" "unprognostic (2.07e-1)" "unprognostic (1.38e-1)" "unprognostic (2.03e-1)" "unprognostic (1.58e-2)" "unprognostic (1.14e-2)" "unprognostic (4.00e-3)" "unprognostic (1.65e-1)" "unprognostic (3.71e-2)" "unprognostic (1.50e-1)" TUBA1B K-ALPHA-1 ENSG00000123416 "Tubulin alpha 1b" P68363 12 49127782-49131397 "Essential proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythrocyte progenitors: 1492.1;Esophageal basal cells: 1765.6;Extravillous trophoblasts: 3078.9;Hofbauer cells: 3042.0;Megakaryocytes: 2862.1;Migrating cytotrophoblasts: 1655.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011513, HPA039247, HPA043684, HPA063394" Enhanced Enhanced "Microtubules,Primary cilium" NA Yes "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 38: Non-specific - Transcription" "Cluster 27: Non-specific - Cell proliferation" 134 Microtubules "Primary cilium" "CAB011513: , HPA039247: , HPA043684: , HPA063394: " "unprognostic (1.63e-3)" "potential prognostic unfavorable (7.53e-5)" "unprognostic (1.81e-2)" "unprognostic (5.38e-3)" "unprognostic (3.43e-2)" "unprognostic (3.44e-1)" "unprognostic (2.30e-1)" "unprognostic (1.32e-1)" "unprognostic (6.19e-3)" "unprognostic (2.67e-3)" "validated prognostic unfavorable (1.22e-6)" "validated prognostic unfavorable (6.78e-6)" "unprognostic (8.72e-3)" "validated prognostic unfavorable (1.97e-9)" "validated prognostic unfavorable (4.90e-5)" "validated prognostic unfavorable (6.52e-6)" "validated prognostic unfavorable (3.96e-5)" "potential prognostic favorable (8.01e-4)" "unprognostic (3.52e-1)" "unprognostic (3.21e-1)" "unprognostic (1.55e-1)" "unprognostic (1.30e-3)" "unprognostic (7.34e-2)" "unprognostic (1.48e-2)" "unprognostic (1.48e-1)" "unprognostic (9.77e-2)" "unprognostic (9.50e-2)" "unprognostic (2.66e-1)" "unprognostic (2.84e-1)" "unprognostic (1.54e-1)" "unprognostic (8.27e-2)" TUBA1C "bcm948, MGC10851, MGC14580, TUBA6" ENSG00000167553 "Tubulin alpha 1c" Q9BQE3 12 49188736-49274600 "Essential proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 435.6" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 1230.3;Esophageal basal cells: 703.3;Esophageal suprabasal cells: 1115.9;Extravillous trophoblasts: 1578.0;Megakaryocytes: 1285.8;Oocytes: 810.5;Suprabasal keratinocytes: 621.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 99.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039247, HPA043684, HPA063394" Supported Enhanced "Microtubules,Primary cilium" NA Yes 220000000 "Cluster 41: Basophils - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 72: Neuronal - Signal transduction" "Cluster 65: Non-specific - Cell growth & division" 97 Microtubules "Primary cilium" "HPA039247: , HPA043684: , HPA063394: " "potential prognostic unfavorable (1.76e-4)" "unprognostic (1.21e-2)" "unprognostic (3.65e-2)" "unprognostic (3.57e-2)" "potential prognostic favorable (9.95e-4)" "unprognostic (2.30e-1)" "unprognostic (2.66e-3)" "potential prognostic unfavorable (1.99e-4)" "unprognostic (2.61e-2)" "unprognostic (2.48e-2)" "validated prognostic unfavorable (3.62e-5)" "validated prognostic unfavorable (9.20e-6)" "unprognostic (6.06e-3)" "validated prognostic unfavorable (3.77e-10)" "validated prognostic unfavorable (3.45e-6)" "validated prognostic unfavorable (2.94e-4)" "validated prognostic unfavorable (1.28e-5)" "unprognostic (1.19e-1)" "unprognostic (2.44e-1)" "unprognostic (4.03e-2)" "unprognostic (1.06e-1)" "potential prognostic unfavorable (5.29e-6)" "unprognostic (5.97e-2)" "unprognostic (1.44e-1)" "unprognostic (1.34e-1)" "unprognostic (2.23e-2)" "unprognostic (2.99e-1)" "unprognostic (2.01e-1)" "unprognostic (1.59e-1)" "unprognostic (3.25e-1)" "unprognostic (3.79e-2)" TUBA3C "bA408E5.3, TUBA2" ENSG00000198033 "Tubulin alpha 3c" P0DPH7 13 19173772-19181824 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 711 "testis: 390.0" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 274.5;Early primary spermatocytes: 526.7;Early spermatids: 627.4;Late primary spermatocytes: 1926.6;Late spermatids: 279.9" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 3.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 25.0;lymphoma: 21.8;Myeloma: 25.3" "Stomach - Parietal cells, Testis - Early spermatids" "Low region specificity" "Detected in single" "HPA039247, HPA043684, HPA063394" Uncertain Enhanced "Microtubules,Primary cilium" NA Yes "Cluster 23: Testis - Spermatogenesis" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 7 Microtubules "Primary cilium" "HPA039247: , HPA043684: , HPA063394: " "unprognostic (7.61e-1)" "potential prognostic unfavorable (4.79e-5)" "unprognostic (5.72e-2)" "unprognostic (3.83e-1)" "unprognostic (9.08e-2)" "unprognostic (5.12e-2)" "unprognostic (1.95e-1)" TUBA3D H2-ALPHA ENSG00000075886 "Tubulin alpha 3d" P0DPH8 2 131476119-131482934 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 16 "heart muscle: 82.4;testis: 211.7" "Group enriched" "Detected in some" 4 "Differentiating spermatogonia: 258.2;Early primary spermatocytes: 593.4;Early spermatids: 299.1;Late primary spermatocytes: 922.3" "Low cell type specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 15.3;Testicular Germ Cell Tumor (TCGA): 11.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Prostate - Prostate glandular cells, Testis - Early spermatids" "Not detected" "Not detected" "CAB004972, HPA039247, HPA043684, HPA063394" Uncertain Enhanced "Microtubules,Primary cilium" NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 60: Prostate cancer - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" Microtubules "Primary cilium" "CAB004972: , HPA039247: , HPA043684: , HPA063394: " "unprognostic (4.57e-3)" "unprognostic (1.38e-2)" "unprognostic (4.05e-2)" "unprognostic (5.83e-2)" "unprognostic (7.07e-2)" "unprognostic (9.94e-3)" "unprognostic (3.25e-1)" "unprognostic (2.29e-1)" "unprognostic (7.16e-2)" "unprognostic (4.35e-1)" "unprognostic (2.30e-1)" TUBA3E ENSG00000152086 "Tubulin alpha 3e" Q6PEY2 2 130191745-130198439 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 17 "heart muscle: 51.2;testis: 169.2" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 147.8;Early primary spermatocytes: 302.8;Early spermatids: 205.2;Late primary spermatocytes: 822.2;Late spermatids: 116.8" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 4.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "thyroid cancer: 1.0" "HPA039247, HPA043684, HPA063394" Uncertain Enhanced "Microtubules,Primary cilium" NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 2: Neurons - Nucleosome" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 3 Microtubules "Primary cilium" "HPA039247: , HPA043684: , HPA063394: " "potential prognostic unfavorable (6.21e-4)" "unprognostic (9.07e-3)" "unprognostic (3.55e-2)" "unprognostic (6.56e-3)" "unprognostic (2.42e-1)" "unprognostic (2.10e-1)" TUBA3FP ENSG00000284130 "Tubulin alpha 3f pseudogene" 22 21008193-21014292 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Cell type enriched" "Detected in single" 7 "Kupffer cells: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "basophil: 6.7" "Lineage enriched" "Detected in many" 5 "granulocytes: 6.7" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 48: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 87: B-cells - Adaptive immunity: Humoral response" TUBA4A "FLJ30169, H2-ALPHA, TUBA1" ENSG00000127824 "Tubulin alpha 4a" P68366 2 219249710-219277902 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Amyotrophic lateral sclerosis, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 345.9;tongue: 249.0" "Cell type enhanced" "Detected in many" "Early spermatids: 574.0;Esophageal apical cells: 418.3;Esophageal suprabasal cells: 573.1;Late spermatids: 1173.7;Megakaryocytes: 982.9;Neutrophils: 407.1;Platelets: 3539.4;Suprabasal keratinocytes: 466.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Kidney - Macrophages, Spleen - Neutrophils_2, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004621, CAB005887, HPA039247, HPA043684, HPA063394" Approved Enhanced "Microtubules,Primary cilium" NA NA 210000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 7: Liver cancer - Metabolism" "Cluster 47: Platelets - Hemostasis" 92 Microtubules "Primary cilium" "CAB004621: , CAB005887: , HPA039247: , HPA043684: , HPA063394: " "unprognostic (4.77e-2)" "unprognostic (7.92e-3)" "unprognostic (2.82e-1)" "unprognostic (2.31e-1)" "unprognostic (1.92e-1)" "unprognostic (2.70e-1)" "unprognostic (9.98e-3)" "unprognostic (2.11e-2)" "unprognostic (5.56e-2)" "unprognostic (2.28e-2)" "unprognostic (1.12e-1)" "unprognostic (5.07e-2)" "unprognostic (1.01e-1)" "potential prognostic unfavorable (3.27e-7)" "unprognostic (7.47e-2)" "potential prognostic unfavorable (1.22e-4)" "unprognostic (1.12e-2)" "unprognostic (2.43e-2)" "unprognostic (7.50e-2)" "unprognostic (2.22e-2)" "unprognostic (4.32e-2)" "unprognostic (5.33e-2)" "unprognostic (5.69e-2)" "unprognostic (2.26e-2)" "unprognostic (2.55e-1)" "unprognostic (9.89e-2)" "unprognostic (1.93e-1)" "unprognostic (3.40e-1)" "unprognostic (2.56e-1)" "unprognostic (6.02e-3)" "unprognostic (1.33e-1)" TUBA4B "FLJ13940, TUBA4" ENSG00000243910 "Tubulin alpha 4b" Q9H853 2 219253243-219272197 "Predicted intracellular proteins" Hydrolase "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 8 "choroid plexus: 21.0;fallopian tube: 37.7" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 190.2;Ependymal cells: 59.1;Epididymal efferent duct ciliated cells: 225.8;Fallopian tube ciliated cells: 315.7;Oocytes: 110.5;Respiratory ciliated cells: 243.8" "Cell type enriched" "Detected in some" 9 "ependymal cell: 71.5" "Cancer enriched" "Detected in some" 5 "Uterine Corpus Endometrial Carcinoma (TCGA): 9.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Testis - Late spermatids" "Low region specificity" "Detected in all" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 15: Kidney cancer - Membrane components" "Cluster 107: Ciliated cells - Cilia assembly & function" "unprognostic (3.07e-1)" "unprognostic (5.57e-2)" "unprognostic (4.60e-2)" "unprognostic (3.64e-1)" "unprognostic (1.29e-1)" "unprognostic (7.95e-2)" "unprognostic (3.27e-2)" "unprognostic (1.33e-2)" "unprognostic (5.25e-3)" TUBA8 TUBAL2 ENSG00000183785 "Tubulin alpha 8" Q9NY65 22 18110100-18146683 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 120.6;skeletal muscle: 311.3;tongue: 144.4" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 28.9;Brain inhibitory neurons: 20.3;Corticotrophs: 8.9;Fibro-adipogenic progenitors: 12.1;Myonuclei: 13.6;Myosatellite cells: 9.7;Other brain neurons: 11.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 16.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 2.8;eosinophil: 2.7;neutrophil: 5.0;NK-cell: 10.4" "Group enriched" "Detected in many" 7 "granulocytes: 5.0;NK-cells: 10.4" "Cancer enhanced" "Detected in many" "Leukemia: 10.1;skin cancer: 10.2" "Heart muscle - Cardiomyocytes, Testis - Late spermatids" "Group enriched" "Detected in all" 4 "cerebellum: 54.7;olfactory bulb: 54.0" "Low region specificity" "Detected in all" "HPA043684, CAB046031, HPA063394" Approved Supported Microtubules NA NA 110000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 15: Non-specific - Transcription" "Cluster 35: RS4;11 - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" 11 Microtubules "CAB046031: , HPA043684: , HPA063394: " "unprognostic (2.15e-1)" "unprognostic (1.18e-1)" "unprognostic (2.40e-1)" "unprognostic (2.66e-2)" "potential prognostic unfavorable (6.19e-4)" "unprognostic (7.62e-2)" "unprognostic (9.36e-2)" "unprognostic (4.35e-2)" "unprognostic (1.90e-2)" "unprognostic (3.59e-2)" "unprognostic (1.22e-1)" "unprognostic (1.03e-1)" "unprognostic (9.44e-2)" "unprognostic (1.53e-2)" "unprognostic (3.16e-1)" "unprognostic (2.32e-1)" "unprognostic (7.01e-3)" "unprognostic (5.52e-2)" "unprognostic (7.34e-2)" "unprognostic (1.89e-2)" "potential prognostic favorable (2.12e-4)" "unprognostic (3.00e-2)" "unprognostic (2.72e-2)" "unprognostic (3.57e-2)" "unprognostic (1.62e-1)" "unprognostic (1.06e-2)" "unprognostic (8.63e-2)" "unprognostic (1.95e-2)" "unprognostic (1.02e-3)" TUBAL3 FLJ21665 ENSG00000178462 "Tubulin alpha like 3" A6NHL2 10 5393101-5404828 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 26.6" "Group enriched" "Detected in some" 4 "Colonocytes: 15.5;Enterocytes: 20.9" "Group enriched" "Detected in some" 19 "choroid plexus epithelial cell: 8.9;endothelial cell: 2.9" "Cancer enhanced" "Detected in some" "Colon Adenocarcinoma (TCGA): 4.7;Rectum Adenocarcinoma (TCGA): 4.7" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 3.7;Gastric cancer: 3.1" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA045900, HPA063394" Uncertain NA NA "Cluster 77: Intestine - Digestion" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 47: Leukemia - Hemostasis" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 2 "HPA045900: , HPA063394: " "unprognostic (1.49e-1)" "unprognostic (1.19e-1)" "unprognostic (6.56e-2)" "potential prognostic favorable (3.00e-4)" "unprognostic (1.37e-1)" "unprognostic (1.48e-1)" "unprognostic (3.36e-2)" TUBB "M40, MGC16435, OK/SW-cl.56, Tubb5" ENSG00000196230 "Tubulin beta class I" P07437 6 30717435-30725538 "Disease related genes, Essential proteins, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bergmann glia: 30.8;Brain excitatory neurons: 61.7;Brain inhibitory neurons: 51.5;Loop of henle epithelial cells: 27.7;Megakaryocytes: 24.7;Microglia: 43.4;Oligodendrocyte progenitor cells: 34.2;Oligodendrocytes: 31.4;Other brain neurons: 170.6;Papillary tip epithelial cells: 33.2;Podocytes: 25.0;Renal collecting duct principal cells: 43.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Prostate - Smooth muscle cells, Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005417, CAB012406, HPA043640, HPA046280" Enhanced Supported "Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Primary cilium tip,Basal body,Flagellar centriole,Principal piece,End piece" Yes Yes 160000000 "Cluster 33: Non-specific - ATP binding" "Cluster 54: Non-specific - Ribosome" "Cluster 44: Non-specific - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 98: Neurons - Neurotransmission & signaling" 211 Microtubules "Cytokinetic bridge, Mitotic spindle, Primary cilium, Primary cilium tip, Basal body, Flagellar centriole, Principal piece, End piece" "CAB005417: , CAB012406: , HPA043640: , HPA046280: " "unprognostic (1.16e-1)" "unprognostic (2.69e-2)" "unprognostic (2.44e-1)" "unprognostic (2.38e-1)" "unprognostic (7.62e-2)" "unprognostic (6.19e-2)" "unprognostic (4.93e-2)" "unprognostic (2.00e-1)" "unprognostic (4.15e-1)" "potential prognostic unfavorable (1.25e-4)" "unprognostic (1.93e-2)" "unprognostic (4.80e-2)" "potential prognostic unfavorable (3.24e-4)" "unprognostic (3.87e-3)" "unprognostic (6.91e-3)" "unprognostic (2.38e-3)" "potential prognostic unfavorable (7.48e-7)" "unprognostic (5.96e-2)" "unprognostic (6.43e-2)" "unprognostic (1.31e-1)" "unprognostic (2.53e-1)" "unprognostic (7.31e-3)" "unprognostic (8.01e-2)" "unprognostic (1.41e-1)" "unprognostic (2.31e-1)" "unprognostic (1.54e-1)" "unprognostic (3.77e-2)" "unprognostic (1.46e-1)" "unprognostic (2.10e-1)" "unprognostic (8.19e-2)" "unprognostic (8.31e-2)" TUBB1 dJ543J19.4 ENSG00000101162 "Tubulin beta 1 class VI" Q9H4B7 20 59019429-59026654 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 8.0;lymphoid tissue: 4.0" "Cell type enriched" "Detected in some" 9 "Platelets: 7732.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 17 "basophil: 63.2;neutrophil: 26.0" "Lineage enriched" "Detected in many" 24 "granulocytes: 63.2" "Cancer enhanced" "Detected in some" "Leukemia: 2.6" "Kidney - Macrophages, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB004286, HPA043640, HPA046280" Approved Supported "Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Primary cilium tip,Basal body,Flagellar centriole,Principal piece,End piece" Yes NA 100000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 6: Non-specific - Immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 47: Platelets - Hemostasis" 19 Microtubules "Cytokinetic bridge, Mitotic spindle, Primary cilium, Primary cilium tip, Basal body, Flagellar centriole, Principal piece, End piece" "CAB004286: , HPA043640: , HPA046280: " "unprognostic (8.33e-2)" "unprognostic (8.05e-2)" "unprognostic (5.68e-2)" "unprognostic (3.40e-2)" TUBB2A "dJ40E16.7, TUBB, TUBB2" ENSG00000137267 "Tubulin beta 2A class IIa" Q13885 6 3153497-3157544 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "brain: 541.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 244.0;Breast myoepithelial cells: 296.2;Epididymal principal cells: 270.5;Esophageal apical cells: 539.0;Esophageal suprabasal cells: 413.6;Ocular epithelial cells: 239.1;Other brain neurons: 381.2;Platelets: 315.1;Retinal horizontal cells: 264.4;Suprabasal keratinocytes: 422.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 304.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 3.2;monocytes: 1.6;T-cells: 3.2" "Cancer enhanced" "Detected in all" "testis cancer: 336.7" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Macrophages, Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015339, HPA043640, HPA046280" Supported Supported "Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Primary cilium tip,Basal body,Flagellar centriole,Principal piece,End piece" Yes NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 24: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 98: Neurons - Neurotransmission & signaling" 70 Microtubules "Cytokinetic bridge, Mitotic spindle, Primary cilium, Primary cilium tip, Basal body, Flagellar centriole, Principal piece, End piece" "CAB015339: , HPA043640: , HPA046280: " "unprognostic (4.09e-3)" "unprognostic (1.81e-1)" "unprognostic (1.62e-1)" "unprognostic (5.17e-2)" "unprognostic (3.24e-1)" "unprognostic (8.04e-2)" "unprognostic (2.86e-2)" "unprognostic (1.58e-1)" "unprognostic (5.85e-2)" "unprognostic (3.22e-2)" "unprognostic (3.14e-1)" "potential prognostic unfavorable (5.26e-5)" "unprognostic (1.35e-1)" "unprognostic (2.45e-3)" "unprognostic (1.88e-1)" "unprognostic (3.87e-2)" "unprognostic (1.63e-2)" "unprognostic (2.16e-1)" "unprognostic (1.55e-1)" "unprognostic (1.61e-2)" "unprognostic (3.59e-1)" "unprognostic (8.80e-3)" "unprognostic (3.90e-2)" "unprognostic (1.71e-3)" "unprognostic (1.27e-2)" "unprognostic (3.49e-1)" "unprognostic (4.03e-3)" "unprognostic (1.17e-2)" "unprognostic (1.57e-1)" "unprognostic (4.80e-3)" "unprognostic (4.12e-2)" TUBB2B "bA506K6.1, DKFZp566F223, MGC8685" ENSG00000137285 "Tubulin beta 2B class IIb" Q9BVA1 6 3223324-3231730 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Neurogenesis "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "brain: 596.1" "Cell type enhanced" "Detected in many" "Astrocytes: 159.3;Bergmann glia: 372.8;Breast myoepithelial cells: 193.7;Ependymal cells: 100.9;Epididymal principal cells: 380.9;Melanocytes: 135.3;Müller glia: 679.0;Myosatellite cells: 110.6;Retinal horizontal cells: 222.4;Schwann cells: 130.8" "Cell type enhanced" "Detected in all" "Bergmann glia: 539.4" "Cancer enriched" "Detected in all" 12 "Glioblastoma Multiforme (TCGA): 842.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 461.5" "Adrenal gland - Adrenal medulla cells, Breast - Breast myoepithelial cells, Kidney - Ascending Loop of Henle cells, Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043640, HPA046280" Supported Supported "Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Primary cilium tip,Basal body,Flagellar centriole,Principal piece,End piece" Yes NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 11: Muller glia cells - Retinal homeostasis" 45 Microtubules "Cytokinetic bridge, Mitotic spindle, Primary cilium, Primary cilium tip, Basal body, Flagellar centriole, Principal piece, End piece" "HPA043640: , HPA046280: " "unprognostic (5.37e-2)" "unprognostic (2.49e-1)" "unprognostic (2.88e-2)" "unprognostic (2.16e-2)" "unprognostic (2.11e-1)" "unprognostic (3.45e-2)" "unprognostic (7.45e-2)" "unprognostic (7.01e-2)" "unprognostic (1.26e-1)" "unprognostic (6.60e-2)" "validated prognostic unfavorable (7.45e-4)" "validated prognostic unfavorable (2.60e-4)" "unprognostic (3.12e-1)" "unprognostic (7.72e-2)" "unprognostic (1.48e-2)" "unprognostic (3.72e-1)" "unprognostic (4.15e-2)" "unprognostic (1.45e-1)" "unprognostic (1.30e-3)" "unprognostic (4.59e-1)" "unprognostic (1.33e-1)" "unprognostic (5.08e-3)" "unprognostic (4.02e-1)" "unprognostic (2.61e-1)" "unprognostic (1.75e-1)" "unprognostic (1.59e-1)" "unprognostic (1.11e-1)" "unprognostic (1.09e-2)" "unprognostic (3.84e-1)" "potential prognostic unfavorable (1.39e-6)" "unprognostic (4.25e-3)" TUBB3 "beta-4, CFEOM3, CFEOM3A, FEOM3" ENSG00000258947 "Tubulin beta 3 class III" Q13509 16 89921392-89938761 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 344.3" "Group enriched" "Detected in some" 8 "Brain excitatory neurons: 88.3;Brain inhibitory neurons: 88.8;Other brain neurons: 290.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "naive B-cell: 2.5" "Lineage enriched" "Detected in single" 9 "B-cells: 2.5" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Colon - Colon enteroendocrine cells, Pituitary gland - Corticotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043640, HPA046280" Approved Supported "Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Primary cilium tip,Basal body,Flagellar centriole,Principal piece,End piece" Yes NA 71000000 "Cluster 10: Brain - Synaptic signal transduction" "Cluster 45: Non-specific - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 98: Neurons - Neurotransmission & signaling" 58 Microtubules "Cytokinetic bridge, Mitotic spindle, Primary cilium, Primary cilium tip, Basal body, Flagellar centriole, Principal piece, End piece" "HPA043640: , HPA046280: " "unprognostic (1.26e-1)" "unprognostic (3.05e-2)" "unprognostic (4.21e-1)" "unprognostic (1.25e-3)" "unprognostic (1.28e-1)" "unprognostic (2.72e-1)" "potential prognostic unfavorable (9.70e-4)" "potential prognostic favorable (3.37e-4)" "unprognostic (4.82e-2)" "unprognostic (1.69e-1)" "validated prognostic unfavorable (3.73e-7)" "validated prognostic unfavorable (1.17e-6)" "unprognostic (1.67e-2)" "unprognostic (1.83e-3)" "unprognostic (9.74e-2)" "unprognostic (2.12e-3)" "unprognostic (1.53e-2)" "unprognostic (2.32e-2)" "unprognostic (1.03e-3)" "unprognostic (5.63e-2)" "unprognostic (1.44e-1)" "unprognostic (3.90e-2)" "potential prognostic unfavorable (1.16e-5)" "unprognostic (6.70e-3)" "unprognostic (7.69e-2)" "unprognostic (4.67e-2)" "unprognostic (8.79e-2)" "unprognostic (5.34e-3)" "unprognostic (1.26e-1)" "unprognostic (2.37e-1)" "unprognostic (6.08e-2)" TUBB4A "beta-5, DYT4, TUBB4" ENSG00000104833 "Tubulin beta 4A class IVa" P04350 19 6494319-6502848 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Dystonia, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 1155.6" "Cell type enhanced" "Detected in some" "Adrenal cortex cells: 39.3;Adrenal medulla cells: 31.9;Brain excitatory neurons: 96.2;Brain inhibitory neurons: 37.1;Epididymal efferent duct absorptive cells: 20.3;Melanocytes: 35.2;Müller glia: 35.0;Oligodendrocytes: 184.3;Other brain neurons: 45.3;Retinal pigment epithelial cells: 85.3;Sertoli cells: 26.8" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 196.1;oligodendrocyte: 221.3;upper rhombic lip: 191.0" "Group enriched" "Detected in many" 4 "Glioblastoma Multiforme (TCGA): 145.4;Skin Cutaneous Melanoma (TCGA): 232.4;Testicular Germ Cell Tumor (TCGA): 150.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 19 "B-cells: 3.8;T-cells: 5.4" "Cancer enhanced" "Detected in many" "skin cancer: 55.0" "Adrenal gland - Adrenal cortex cells, Colon - Colon enteroendocrine cells, Pituitary gland - Undifferentiated cells (Pituitary gland)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010768, HPA043640, HPA046280" Approved Supported "Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Primary cilium tip,Basal body,Flagellar centriole,Principal piece,End piece" Yes NA 100000000 "Cluster 24: Non-specific - Transcription" "Cluster 27: Cerebellum - Synaptic function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 42 Microtubules "Cytokinetic bridge, Mitotic spindle, Primary cilium, Primary cilium tip, Basal body, Flagellar centriole, Principal piece, End piece" "CAB010768: , HPA043640: , HPA046280: " "unprognostic (1.18e-2)" "unprognostic (5.93e-2)" "unprognostic (6.56e-3)" "unprognostic (2.98e-1)" "unprognostic (5.14e-2)" "unprognostic (1.50e-1)" "unprognostic (4.89e-2)" "unprognostic (4.12e-2)" "unprognostic (1.56e-1)" "unprognostic (7.55e-3)" "unprognostic (5.13e-2)" "unprognostic (7.25e-2)" "potential prognostic favorable (9.68e-4)" "unprognostic (1.05e-1)" "unprognostic (1.80e-3)" "unprognostic (1.01e-1)" "potential prognostic unfavorable (1.40e-4)" "unprognostic (5.37e-2)" "unprognostic (6.72e-2)" "unprognostic (2.66e-1)" "unprognostic (6.76e-2)" "unprognostic (1.91e-1)" "potential prognostic unfavorable (2.36e-4)" TUBB4B "Beta2, TUBB2C" ENSG00000188229 "Tubulin beta 4B class IVb" P68371 9 137241287-137243707 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Deafness, Disease variant, FDA approved drug targets, Leber congenital amaurosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 2019.1;Esophageal apical cells: 2023.6;Fallopian tube ciliated cells: 2624.7;Late primary spermatocytes: 3642.4;Late spermatids: 4003.9;Respiratory ciliated cells: 2676.7" "Cell type enhanced" "Detected in all" "ependymal cell: 488.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Kidney - Macrophages, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010880, HPA043640, HPA046280" Enhanced Approved "Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Primary cilium tip,Basal body,Flagellar centriole,Principal piece,End piece" Yes Yes 130000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 44: Non-specific - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 20: Non-specific - Transcription regulation" 173 Microtubules "Cytokinetic bridge, Mitotic spindle, Primary cilium, Primary cilium tip, Basal body, Flagellar centriole, Principal piece, End piece" "CAB010880: , HPA043640: , HPA046280: " "unprognostic (2.76e-2)" "unprognostic (2.58e-1)" "unprognostic (1.01e-2)" "unprognostic (7.18e-2)" "unprognostic (2.64e-1)" "unprognostic (3.59e-2)" "unprognostic (1.98e-1)" "unprognostic (7.37e-2)" "unprognostic (1.00e-1)" "unprognostic (3.98e-2)" "unprognostic (2.21e-1)" "unprognostic (5.77e-2)" "potential prognostic unfavorable (3.19e-4)" "unprognostic (5.16e-3)" "unprognostic (6.06e-3)" "unprognostic (6.26e-2)" "unprognostic (3.00e-2)" "unprognostic (1.89e-1)" "unprognostic (2.38e-2)" "unprognostic (3.72e-1)" "unprognostic (1.67e-1)" "unprognostic (1.74e-1)" "unprognostic (6.58e-2)" "unprognostic (2.32e-1)" "unprognostic (2.97e-1)" "unprognostic (1.14e-2)" "unprognostic (4.60e-2)" "potential prognostic favorable (2.12e-4)" "unprognostic (4.44e-2)" TUBB6 "HsT1601, MGC4083" ENSG00000176014 "Tubulin beta 6 class V" Q9BUF5 18 12307669-12344320 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 376.0;Cardiomyocytes: 321.8;Decidual stromal cells: 381.5;Esophageal apical cells: 1568.3;Esophageal suprabasal cells: 484.6;Extravillous trophoblasts: 829.5;Smooth muscle cells: 326.6" "Cell type enhanced" "Detected in all" "endothelial cell: 72.1;pericyte: 50.2;vascular associated smooth muscle cell: 104.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 157.2" "Group enriched" "Detected in many" 6 "B-cells: 58.8;dendritic cells: 157.2" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1" "Region enriched" "Detected in many" 6 "olfactory bulb: 19.9" "Region enhanced" "Detected in all" "spinal cord: 14.0" "HPA043640, HPA046280" Approved Approved "Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Primary cilium tip,Basal body,Flagellar centriole,Principal piece,End piece" Yes Yes 51000000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 12: Non-specific - Vasculature" "Cluster 72: Neuronal - Signal transduction" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 47 Microtubules "Cytokinetic bridge, Mitotic spindle, Primary cilium, Primary cilium tip, Basal body, Flagellar centriole, Principal piece, End piece" "HPA043640: , HPA046280: " "unprognostic (3.00e-2)" "unprognostic (6.47e-2)" "unprognostic (2.30e-2)" "unprognostic (4.26e-3)" "unprognostic (1.38e-2)" "unprognostic (1.70e-1)" "unprognostic (7.82e-2)" "unprognostic (6.95e-2)" "unprognostic (1.01e-3)" "unprognostic (2.51e-1)" "unprognostic (3.74e-2)" "unprognostic (4.12e-2)" "unprognostic (3.95e-3)" "unprognostic (6.25e-2)" "unprognostic (6.13e-2)" "unprognostic (3.65e-3)" "unprognostic (5.96e-3)" "unprognostic (7.86e-2)" "unprognostic (5.77e-2)" "unprognostic (5.29e-3)" "unprognostic (1.22e-1)" "unprognostic (4.33e-2)" "unprognostic (4.69e-3)" "unprognostic (2.68e-1)" "unprognostic (1.07e-2)" "unprognostic (3.94e-2)" "unprognostic (4.81e-2)" "unprognostic (1.84e-3)" "unprognostic (2.27e-1)" "unprognostic (3.48e-2)" "potential prognostic unfavorable (5.09e-4)" TUBB8 bA631M21.2 ENSG00000261456 "Tubulin beta 8 class VIII" Q3ZCM7 10 46888-74163 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "ovary: 2.3;testis: 1.7" "Cell type enriched" "Detected in some" 30 "Oocytes: 534.2" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 9.6" "Cancer enriched" "Detected in single" 5 "Testicular Germ Cell Tumor (TCGA): 4.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043640, HPA046280" Uncertain Supported "Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Primary cilium tip,Basal body,Flagellar centriole,Principal piece,End piece" Yes NA "Cluster 75: Ovary - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 41: Oocytes - Oogenesis" 103 Microtubules "Cytokinetic bridge, Mitotic spindle, Primary cilium, Primary cilium tip, Basal body, Flagellar centriole, Principal piece, End piece" "HPA043640: , HPA046280: " "unprognostic (2.25e-1)" "unprognostic (7.99e-2)" TUBB8B TUBB8P12 ENSG00000173213 "Tubulin beta 8B" A6NNZ2 18 47221-73545 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "ovary: 1.5;testis: 4.3" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 39.8;Early primary spermatocytes: 46.6;Oocytes: 161.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 4.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043640, HPA046280" Uncertain Approved "Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Primary cilium tip,Basal body,Flagellar centriole,Principal piece,End piece" Yes NA "Cluster 79: Testis - Spermatogenesis" "Cluster 18: Liver cancer - Metabolism" "Cluster 41: Oocytes - Oogenesis" 6 Microtubules "Cytokinetic bridge, Mitotic spindle, Primary cilium, Primary cilium tip, Basal body, Flagellar centriole, Principal piece, End piece" "HPA043640: , HPA046280: " "unprognostic (2.75e-1)" "unprognostic (1.77e-1)" TUBD1 "FLJ12709, TUBD" ENSG00000108423 "Tubulin delta 1" Q9UJT1 17 59859479-59892945 "FDA approved drug targets, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Developmental protein" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 96.4;Myonuclei: 103.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004609, HPA023980, HPA027090" Approved Approved Nucleoplasm,Cytosol NA Yes "Cluster 3: Non-specific - Nuclear processes" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 25: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 51: Secretory epithelial cells - Mixed function" 8 "Nucleoplasm, Cytosol" "CAB004609: , HPA023980: , HPA027090: " "unprognostic (3.24e-2)" "unprognostic (2.14e-1)" "unprognostic (1.36e-1)" "unprognostic (4.67e-2)" "unprognostic (1.06e-2)" "unprognostic (1.58e-1)" "unprognostic (1.70e-1)" "unprognostic (1.99e-2)" "unprognostic (6.97e-2)" "unprognostic (2.74e-2)" "unprognostic (2.56e-3)" "potential prognostic favorable (2.50e-4)" "unprognostic (7.33e-2)" "potential prognostic unfavorable (1.87e-5)" "unprognostic (1.34e-3)" "unprognostic (2.62e-1)" "unprognostic (1.79e-2)" "unprognostic (1.80e-2)" "unprognostic (1.66e-3)" "unprognostic (3.41e-2)" "unprognostic (5.89e-3)" "unprognostic (1.06e-2)" "unprognostic (5.29e-3)" "unprognostic (1.65e-1)" "unprognostic (1.58e-2)" "unprognostic (7.42e-2)" "unprognostic (1.06e-2)" "unprognostic (9.02e-2)" "unprognostic (5.05e-2)" "unprognostic (1.38e-1)" "unprognostic (4.90e-2)" TUBE1 "dJ142L7.2, FLJ22589, TUBE" ENSG00000074935 "Tubulin epsilon 1" Q9UJT0 6 112070663-112087529 "FDA approved drug targets, Predicted intracellular proteins" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 217.6;Hepatocytes: 102.3;Late primary spermatocytes: 216.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA032073, HPA032074" Approved NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 55: Non-specific - Transcription" "Cluster 13: Non-specific - Mixed function" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 2 "HPA032073: , HPA032074: " "unprognostic (3.82e-2)" "unprognostic (4.19e-2)" "unprognostic (2.31e-1)" "unprognostic (1.23e-1)" "unprognostic (1.19e-1)" "unprognostic (1.46e-1)" "unprognostic (4.09e-2)" "unprognostic (1.23e-2)" "unprognostic (4.62e-2)" "unprognostic (2.24e-2)" "unprognostic (1.49e-1)" "unprognostic (8.25e-2)" "unprognostic (2.92e-1)" "unprognostic (5.38e-2)" "unprognostic (5.58e-3)" "unprognostic (6.95e-2)" "unprognostic (1.26e-1)" "unprognostic (1.21e-1)" "unprognostic (6.00e-3)" "unprognostic (3.18e-2)" "unprognostic (1.78e-1)" "potential prognostic favorable (4.26e-5)" "unprognostic (8.42e-3)" "unprognostic (2.12e-1)" "unprognostic (1.30e-3)" "unprognostic (3.09e-2)" "unprognostic (2.41e-1)" "unprognostic (1.78e-1)" "unprognostic (1.40e-1)" "unprognostic (1.65e-1)" "unprognostic (2.59e-2)" TUBG1 "TUBG, TUBGCP1" ENSG00000131462 "Tubulin gamma 1" P23258 17 42609641-42615238 "Disease related genes, Essential proteins, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, FDA approved drug targets, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 155.1" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 292.3;Early spermatids: 753.9;Erythrocyte progenitors: 183.6;Late primary spermatocytes: 424.4;Late spermatids: 709.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004608, HPA043012" Enhanced Approved "Principal piece" NA Yes "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 39: Testis - Nuclear processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 82 "Principal piece" "CAB004608: , HPA043012: " "unprognostic (1.46e-2)" "unprognostic (2.65e-2)" "unprognostic (3.19e-1)" "unprognostic (1.07e-2)" "unprognostic (1.39e-2)" "unprognostic (5.18e-3)" "unprognostic (7.46e-3)" "unprognostic (1.25e-2)" "unprognostic (1.13e-1)" "unprognostic (2.97e-2)" "unprognostic (4.26e-1)" "unprognostic (2.36e-3)" "unprognostic (6.88e-2)" "validated prognostic unfavorable (1.03e-10)" "validated prognostic unfavorable (1.50e-6)" "validated prognostic unfavorable (3.40e-4)" "validated prognostic unfavorable (5.01e-4)" "unprognostic (4.03e-2)" "unprognostic (4.22e-2)" "unprognostic (1.01e-1)" "unprognostic (2.07e-1)" "unprognostic (1.13e-1)" "unprognostic (4.46e-3)" "unprognostic (2.09e-1)" "unprognostic (6.20e-2)" "unprognostic (1.28e-1)" "unprognostic (4.02e-2)" "unprognostic (2.22e-1)" "unprognostic (1.73e-1)" "unprognostic (2.63e-2)" "unprognostic (8.79e-2)" TUBG2 ENSG00000037042 "Tubulin gamma 2" Q9NRH3 17 42659284-42667006 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 120.4" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 56.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011495, HPA043012" Approved Supported "Centriolar satellite,Principal piece" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 36: Brain & Liver - Signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 94: Gonadal somatic cells - Mixed function" 19 "Centriolar satellite, Principal piece" "CAB011495: , HPA043012: " "unprognostic (3.40e-1)" "unprognostic (6.11e-2)" "unprognostic (7.90e-2)" "unprognostic (5.42e-2)" "unprognostic (4.37e-2)" "unprognostic (7.01e-2)" "unprognostic (1.03e-3)" "unprognostic (2.60e-1)" "unprognostic (1.76e-1)" "unprognostic (3.16e-1)" "unprognostic (2.23e-2)" "unprognostic (1.54e-1)" "unprognostic (5.14e-2)" "potential prognostic unfavorable (1.22e-4)" "unprognostic (1.68e-2)" "unprognostic (3.27e-2)" "unprognostic (3.56e-2)" "unprognostic (3.07e-1)" "unprognostic (1.63e-1)" "unprognostic (2.35e-2)" "unprognostic (1.87e-1)" "unprognostic (3.01e-3)" "unprognostic (1.14e-2)" "unprognostic (1.04e-1)" "unprognostic (1.37e-1)" "unprognostic (4.11e-3)" "unprognostic (1.09e-2)" "unprognostic (4.12e-3)" "unprognostic (9.67e-2)" "unprognostic (9.93e-2)" "unprognostic (9.74e-2)" TUBGCP2 "GCP2, SPBC97, Spc97p" ENSG00000130640 "Tubulin gamma complex associated protein 2" Q9BSJ2 10 133278635-133318823 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Epilepsy, Intellectual disability, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 259.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037885 Approved Supported "Nucleoplasm,Centrosome,Basal body" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 70: Non-specific - Protein processing" "Cluster 45: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 34 "Centrosome, Basal body" Nucleoplasm "HPA037885: " "unprognostic (2.91e-1)" "unprognostic (5.85e-2)" "unprognostic (1.09e-1)" "unprognostic (3.01e-1)" "unprognostic (1.11e-1)" "unprognostic (3.63e-2)" "unprognostic (3.13e-1)" "unprognostic (1.62e-3)" "unprognostic (1.06e-1)" "unprognostic (1.79e-2)" "unprognostic (7.43e-3)" "unprognostic (1.72e-1)" "potential prognostic favorable (4.38e-4)" "unprognostic (6.01e-2)" "unprognostic (3.15e-1)" "unprognostic (2.06e-1)" "unprognostic (7.25e-3)" "unprognostic (1.23e-1)" "unprognostic (2.34e-1)" "unprognostic (4.30e-2)" "unprognostic (4.49e-2)" "unprognostic (1.44e-1)" "unprognostic (3.74e-2)" "unprognostic (3.26e-2)" "unprognostic (2.03e-1)" "unprognostic (2.23e-3)" "unprognostic (1.91e-2)" "unprognostic (1.76e-1)" "unprognostic (2.18e-2)" "unprognostic (1.14e-1)" "unprognostic (3.19e-2)" TUBGCP3 "GCP3, SPBC98, Spc98p" ENSG00000126216 "Tubulin gamma complex associated protein 3" Q96CW5 13 112485011-112588205 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043913 Approved NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 15: Bone marrow - Innate immune response" "Cluster 30: White matter - Myelination" "Cluster 19: Non-specific - Unknown function" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 17 "HPA043913: " "unprognostic (2.44e-1)" "unprognostic (2.50e-1)" "unprognostic (1.15e-1)" "unprognostic (1.29e-1)" "unprognostic (1.68e-1)" "unprognostic (4.65e-2)" "unprognostic (1.20e-1)" "unprognostic (2.55e-2)" "unprognostic (2.25e-1)" "unprognostic (1.98e-1)" "potential prognostic favorable (5.19e-5)" "unprognostic (4.08e-3)" "unprognostic (8.59e-2)" "unprognostic (2.57e-2)" "unprognostic (1.66e-1)" "unprognostic (1.09e-2)" "unprognostic (8.87e-3)" "unprognostic (1.20e-2)" "unprognostic (2.91e-1)" "unprognostic (5.23e-2)" "unprognostic (3.04e-1)" "unprognostic (4.48e-2)" "unprognostic (3.80e-2)" "unprognostic (1.04e-1)" "unprognostic (1.76e-1)" "unprognostic (2.16e-2)" "unprognostic (5.18e-3)" "unprognostic (2.42e-1)" "unprognostic (1.10e-1)" "unprognostic (4.32e-2)" "unprognostic (3.76e-3)" TUBGCP4 "76P, FLJ14797" ENSG00000137822 "Tubulin gamma complex associated protein 4" Q9UGJ1 15 43369221-43409771 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Intellectual disability, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 78.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 13.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043212 Approved Supported Centrosome NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 5: Non-specific - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 29 Centrosome "HPA043212: " "unprognostic (1.73e-2)" "unprognostic (1.00e-2)" "unprognostic (3.57e-1)" "unprognostic (9.18e-2)" "unprognostic (1.47e-1)" "unprognostic (1.29e-1)" "unprognostic (2.46e-2)" "unprognostic (1.90e-3)" "unprognostic (1.05e-1)" "potential prognostic unfavorable (1.27e-4)" "potential prognostic favorable (2.01e-4)" "unprognostic (3.48e-3)" "unprognostic (1.83e-1)" "unprognostic (3.75e-2)" "unprognostic (4.54e-2)" "unprognostic (1.25e-1)" "unprognostic (1.83e-2)" "unprognostic (6.82e-2)" "unprognostic (4.90e-2)" "unprognostic (8.93e-2)" "unprognostic (2.33e-1)" "unprognostic (1.34e-2)" "unprognostic (3.69e-2)" "unprognostic (7.86e-2)" "unprognostic (2.87e-3)" "unprognostic (2.53e-1)" "unprognostic (1.66e-1)" "unprognostic (3.41e-2)" "unprognostic (1.15e-1)" "unprognostic (1.24e-1)" "unprognostic (5.07e-2)" TUBGCP5 "GCP5, KIAA1899" ENSG00000275835 "Tubulin gamma complex associated protein 5" Q96RT8 15 22983192-23039572 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bergmann glia: 31.7;Brain inhibitory neurons: 36.3;Distal convoluted tubule cells: 34.2;Loop of henle epithelial cells: 33.0;Microglia: 42.1;Oligodendrocytes: 37.5;Other brain neurons: 37.5;Proximal tubule cells: 34.2;Renal collecting duct principal cells: 33.9;Renal connecting tubule cells: 32.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039366, HPA040366" Supported Supported "Primary cilium,Primary cilium transition zone,Centrosome,Basal body,Cytosol" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 61: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 102: Non-specific - Mixed function" 27 "Centrosome, Basal body" "Primary cilium, Primary cilium transition zone, Cytosol" "HPA039366: , HPA040366: " "unprognostic (6.18e-2)" "unprognostic (3.36e-3)" "unprognostic (2.99e-2)" "unprognostic (4.01e-1)" "unprognostic (5.11e-2)" "unprognostic (1.60e-1)" "unprognostic (1.27e-1)" "unprognostic (2.23e-1)" "unprognostic (2.12e-2)" "unprognostic (3.42e-1)" "unprognostic (1.10e-1)" "unprognostic (3.17e-1)" "unprognostic (8.34e-2)" "unprognostic (1.63e-1)" "unprognostic (2.10e-1)" "unprognostic (8.00e-2)" "unprognostic (9.33e-2)" "unprognostic (1.17e-2)" "unprognostic (1.22e-1)" "unprognostic (2.02e-1)" "unprognostic (3.43e-1)" "unprognostic (1.38e-1)" "unprognostic (2.33e-1)" "unprognostic (1.54e-1)" "unprognostic (1.06e-2)" "unprognostic (1.15e-2)" "unprognostic (1.11e-1)" "unprognostic (1.93e-1)" TUBGCP6 "DJ402G11.6, GCP6, KIAA1669" ENSG00000128159 "Tubulin gamma complex associated protein 6" Q96RT7 22 50217689-50245023 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 50.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043928 Approved NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 64: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 8 "HPA043928: " "unprognostic (3.72e-2)" "unprognostic (5.04e-2)" "unprognostic (1.47e-2)" "unprognostic (2.57e-3)" "unprognostic (2.74e-1)" "unprognostic (1.16e-1)" "unprognostic (2.72e-1)" "unprognostic (2.24e-3)" "unprognostic (4.02e-2)" "unprognostic (2.16e-1)" "unprognostic (1.54e-1)" "unprognostic (4.36e-2)" "potential prognostic favorable (1.30e-5)" "unprognostic (4.56e-1)" "unprognostic (4.53e-2)" "unprognostic (1.36e-2)" "unprognostic (5.06e-1)" "unprognostic (1.03e-1)" "unprognostic (1.26e-1)" "unprognostic (4.12e-3)" "unprognostic (3.48e-2)" "potential prognostic favorable (2.38e-4)" "unprognostic (5.51e-2)" "unprognostic (1.59e-1)" "unprognostic (1.16e-1)" "unprognostic (1.53e-3)" "unprognostic (2.24e-1)" "unprognostic (6.08e-2)" "unprognostic (2.48e-2)" "unprognostic (1.17e-1)" "unprognostic (1.95e-1)" TUFM "EF-TuMT, EFTu" ENSG00000178952 "Tu translation elongation factor, mitochondrial" P49411 16 28842411-28846348 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Elongation factor, Hydrolase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 529.6;Late spermatids: 1008.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018991, HPA024087, CAB075730, CAB075731, CAB075732" Enhanced Enhanced Mitochondria NA NA 550000 "Cluster 13: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 54: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 71 Mitochondria "CAB075730: , CAB075731: , CAB075732: , HPA018991: , HPA024087: " "unprognostic (1.34e-3)" "unprognostic (9.06e-2)" "unprognostic (5.85e-2)" "unprognostic (2.89e-1)" "unprognostic (8.62e-2)" "unprognostic (1.78e-2)" "unprognostic (1.36e-1)" "unprognostic (1.46e-1)" "unprognostic (2.89e-2)" "unprognostic (1.82e-1)" "potential prognostic favorable (1.17e-4)" "unprognostic (1.46e-1)" "unprognostic (1.06e-2)" "unprognostic (7.78e-3)" "unprognostic (1.72e-2)" "unprognostic (9.80e-2)" "unprognostic (4.38e-2)" "unprognostic (1.58e-1)" "unprognostic (3.84e-1)" "unprognostic (1.34e-1)" "unprognostic (1.04e-1)" "unprognostic (1.09e-1)" "unprognostic (2.07e-1)" "unprognostic (2.28e-1)" "unprognostic (2.24e-2)" "unprognostic (3.79e-2)" "unprognostic (5.55e-2)" "unprognostic (2.74e-1)" "unprognostic (7.45e-2)" "unprognostic (4.26e-3)" "unprognostic (4.01e-2)" TUFT1 ENSG00000143367 "Tuftelin 1" Q9NNX1 1 151540305-151583583 "Predicted intracellular proteins, Predicted secreted proteins" Biomineralization "Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 105.2" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 144.5;Esophageal apical cells: 201.2;Esophageal suprabasal cells: 102.8;Ocular epithelial cells: 153.5;Renal connecting tubule cells: 99.3;Suprabasal keratinocytes: 98.3;Urothelial cells: 104.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 5.2" "Group enriched" "Detected in many" 5 "granulocytes: 5.2;T-cells: 3.5" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebellum: 50.7" "HPA028112, HPA054301" Approved Approved Approved Vesicles "Secreted - unknown location" Other NA Yes "Cluster 33: Non-specific - ATP binding" "Cluster 58: Skin - Keratinization" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 12 Vesicles "HPA028112: , HPA054301: " "unprognostic (1.35e-1)" "unprognostic (2.08e-2)" "unprognostic (3.59e-1)" "unprognostic (1.82e-1)" "unprognostic (1.58e-1)" "unprognostic (2.54e-2)" "unprognostic (9.66e-3)" "unprognostic (1.86e-1)" "unprognostic (1.09e-1)" "unprognostic (1.67e-2)" "unprognostic (1.61e-3)" "unprognostic (2.00e-1)" "potential prognostic unfavorable (2.56e-4)" "unprognostic (3.75e-2)" "unprognostic (9.64e-3)" "unprognostic (1.54e-2)" "unprognostic (3.16e-2)" "unprognostic (2.40e-2)" "unprognostic (1.22e-2)" "unprognostic (4.17e-1)" "unprognostic (2.49e-1)" "unprognostic (2.44e-3)" "unprognostic (1.24e-1)" "unprognostic (7.58e-2)" "unprognostic (7.93e-2)" "unprognostic (4.14e-2)" "unprognostic (3.72e-3)" "unprognostic (8.82e-2)" "unprognostic (4.82e-2)" "unprognostic (1.42e-2)" "unprognostic (9.38e-2)" TUG1 "FLJ20618, LINC00080, NCRNA00080" ENSG00000253352 "Taurine up-regulated 1" A0A6I8PU40 22 30969245-30979395 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 64: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 7: Non-specific - Transcription" "unprognostic (1.81e-1)" "unprognostic (6.40e-2)" "potential prognostic favorable (1.37e-4)" "unprognostic (1.77e-1)" "unprognostic (3.19e-2)" "unprognostic (7.71e-2)" "unprognostic (8.86e-3)" "unprognostic (2.66e-1)" "unprognostic (2.30e-1)" "unprognostic (5.09e-2)" "potential prognostic favorable (7.04e-4)" "unprognostic (4.16e-3)" "unprognostic (3.96e-1)" "potential prognostic unfavorable (2.75e-4)" "unprognostic (2.10e-1)" "unprognostic (2.81e-1)" "unprognostic (1.84e-1)" "unprognostic (8.54e-2)" "unprognostic (1.98e-3)" "unprognostic (7.43e-2)" "unprognostic (6.96e-2)" "unprognostic (7.21e-2)" "potential prognostic unfavorable (1.49e-4)" "unprognostic (3.10e-1)" "unprognostic (2.01e-2)" "unprognostic (1.33e-1)" "unprognostic (2.84e-3)" "unprognostic (2.36e-1)" "unprognostic (2.08e-1)" "unprognostic (3.62e-3)" "unprognostic (1.09e-1)" TULP1 "LCA15, RP14, TUBL1" ENSG00000112041 "TUB like protein 1" O00294 6 35497874-35512896 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Phagocytosis, Sensory transduction, Vision" "Disease variant, Leber congenital amaurosis, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 170 "retina: 194.3" "Group enriched" "Detected in some" 9 "Cone photoreceptor cells: 370.6;Rod photoreceptor cells: 427.0" "Cell type enriched" "Detected in single" 8 "fibroblast: 4.0" "Cancer enhanced" "Detected in single" "Testicular Germ Cell Tumor (TCGA): 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Brain cancer: 1.0" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Not detected" "Not detected" "Intracellular and membrane" Other NA NA "Cluster 42: Retina - Visual perception" "Cluster 1: Neuronal - Visual perception" "Cluster 79: Photoreceptor cells - Phototransduction" 2 "unprognostic (2.72e-2)" TULP2 "CT65, TUBL2" ENSG00000104804 "TUB like protein 2" O00295 19 48880965-48898744 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 31 "testis: 29.4" "Cell type enhanced" "Detected in many" "Early spermatids: 255.6;Endometrial luminal cells: 107.2;Epicardial cells: 122.8;Late primary spermatocytes: 299.6;Late spermatids: 373.0;Mast cells: 129.5;Medullary thymic epithelial cells: 108.0;Neutrophils: 240.2" "Cell type enhanced" "Detected in some" "vascular associated smooth muscle cell: 4.0" "Cancer enriched" "Detected in single" 5 "Testicular Germ Cell Tumor (TCGA): 4.4" "Region enhanced" "Detected in many" "cerebral cortex: 6.4" "Immune cell enriched" "Detected in single" 13 "plasmacytoid DC: 1.3" "Lineage enriched" "Detected in single" 13 "dendritic cells: 1.3" "Not detected" "Not detected" "Prostate - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA075828 Approved Cytosol "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 53: Neurons - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 4 Cytosol "HPA075828: " "unprognostic (9.82e-2)" "unprognostic (3.90e-3)" "unprognostic (2.16e-1)" TULP3 TUBL3 ENSG00000078246 "TUB like protein 3" O75386 12 2877223-2941138 "Disease related genes, Predicted intracellular proteins" "Developmental protein" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Retinal horizontal cells: 180.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 76.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Spleen - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015285, HPA018496" Uncertain Supported "Nucleoplasm,Nucleoli,Plasma membrane,Mitotic spindle,Primary cilium,Primary cilium transition zone,Basal body" "Intracellular and membrane" "Developmental protein" Yes NA "Cluster 14: Non-specific - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 55: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 94: Gonadal somatic cells - Mixed function" 70 "Nucleoplasm, Primary cilium" "Nucleoli, Plasma membrane, Mitotic spindle, Primary cilium transition zone, Basal body" "HPA015285: , HPA018496: " "unprognostic (1.58e-2)" "unprognostic (1.34e-1)" "unprognostic (1.27e-1)" "unprognostic (5.39e-2)" "unprognostic (1.38e-1)" "unprognostic (1.88e-3)" "unprognostic (1.67e-1)" "unprognostic (1.27e-1)" "unprognostic (1.94e-2)" "unprognostic (6.20e-3)" "unprognostic (2.28e-2)" "unprognostic (6.01e-2)" "unprognostic (3.61e-1)" "potential prognostic unfavorable (4.20e-5)" "unprognostic (3.16e-2)" "unprognostic (4.20e-2)" "potential prognostic unfavorable (6.73e-4)" "unprognostic (8.01e-2)" "unprognostic (5.19e-2)" "unprognostic (1.04e-1)" "unprognostic (1.30e-1)" "unprognostic (4.09e-2)" "unprognostic (5.94e-2)" "unprognostic (1.96e-1)" "unprognostic (2.79e-2)" "unprognostic (1.73e-3)" "unprognostic (7.51e-2)" "unprognostic (1.29e-1)" "unprognostic (1.84e-1)" "unprognostic (3.36e-2)" "unprognostic (2.64e-2)" TULP4 "KIAA1397, TUSP" ENSG00000130338 "TUB like protein 4" Q9NRJ4 6 158232236-158511828 "Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 409.9;Oligodendrocytes: 322.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005445 Approved Approved "Acrosome,Principal piece" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" 7 "Principal piece" Acrosome "HPA005445: " "unprognostic (1.40e-2)" "potential prognostic unfavorable (9.08e-4)" "unprognostic (1.99e-2)" "unprognostic (1.92e-2)" "unprognostic (1.41e-1)" "unprognostic (2.54e-3)" "unprognostic (2.63e-1)" "potential prognostic favorable (3.58e-5)" "unprognostic (1.65e-1)" "unprognostic (2.41e-1)" "potential prognostic favorable (7.75e-6)" "unprognostic (6.52e-3)" "unprognostic (1.42e-1)" "unprognostic (2.31e-2)" "unprognostic (2.90e-2)" "unprognostic (2.00e-1)" "unprognostic (3.26e-1)" "unprognostic (1.87e-1)" "unprognostic (4.23e-2)" "unprognostic (1.35e-2)" "unprognostic (8.59e-2)" "unprognostic (4.01e-2)" "unprognostic (1.33e-1)" "unprognostic (1.68e-1)" "unprognostic (2.57e-3)" "unprognostic (1.58e-3)" "unprognostic (2.35e-1)" "unprognostic (3.23e-1)" "unprognostic (1.90e-1)" "unprognostic (3.91e-1)" "unprognostic (3.48e-1)" TUNAR "BNLN, HI-LNC78, LINC00617, TUNA" ENSG00000250366 "TCL1 upstream neural differentiation-associated RNA" A0A1B0GTB2 14 95866587-95925663 "Predicted membrane proteins" Neurogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 48.4" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 10.3;Brain inhibitory neurons: 20.3;Early spermatids: 11.8;Endometrial luminal cells: 39.5;Epididymal efferent duct absorptive cells: 12.5;Epididymal efferent duct ciliated cells: 8.8;Gonadotrophs: 11.3;Oocytes: 13.8;Other brain neurons: 13.2;Pancreatic islet cells: 47.5;Retinal amacrine cells: 23.8;Undifferentiated spermatogonia: 8.2" "Cell type enhanced" "Detected in many" "lower rhombic lip: 55.9" "Group enriched" "Detected in some" 4 "Kidney Renal Papillary Cell Carcinoma (TCGA): 8.9;Ovary Serous Cystadenocarcinoma (TCGA): 2.2;Pancreatic Adenocarcinoma (TCGA): 2.5;Testicular Germ Cell Tumor (TCGA): 5.9;Uterine Corpus Endometrial Carcinoma (TCGA): 5.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Spermatogonia, Thyroid gland - Parafollicular cells" "Low region specificity" "Detected in all" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 49: Hindbrain - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" "unprognostic (7.69e-2)" "potential prognostic favorable (1.12e-4)" "unprognostic (1.44e-1)" "unprognostic (4.82e-2)" "unprognostic (1.22e-2)" "unprognostic (1.40e-1)" "unprognostic (4.07e-2)" "unprognostic (1.58e-1)" "unprognostic (4.26e-2)" TUSC1 "CCDC89B, TSG-9" ENSG00000198680 "Tumor suppressor candidate 1" Q2TAM9 9 25676969-25678444 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal clear cells: 112.3;Late primary spermatocytes: 294.1" "Cell type enhanced" "Detected in many" "pericyte: 45.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051426 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 27: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 1 Vesicles Nucleoplasm "HPA051426: " "unprognostic (1.10e-1)" "unprognostic (2.79e-1)" "unprognostic (8.88e-2)" "unprognostic (2.83e-1)" "unprognostic (6.33e-2)" "unprognostic (7.18e-2)" "potential prognostic unfavorable (1.47e-4)" "unprognostic (2.62e-1)" "unprognostic (1.64e-1)" "unprognostic (3.73e-2)" "potential prognostic favorable (1.10e-6)" "unprognostic (2.83e-3)" "unprognostic (1.34e-2)" "unprognostic (1.20e-2)" "unprognostic (2.61e-3)" "unprognostic (1.37e-1)" "unprognostic (1.59e-1)" "potential prognostic unfavorable (7.96e-4)" "unprognostic (3.62e-2)" "unprognostic (6.30e-3)" "unprognostic (6.45e-2)" "unprognostic (3.94e-3)" "unprognostic (2.91e-2)" "unprognostic (2.74e-1)" "unprognostic (2.35e-1)" "unprognostic (4.13e-3)" "unprognostic (1.11e-1)" "unprognostic (2.63e-1)" "unprognostic (2.03e-1)" "unprognostic (1.06e-1)" "unprognostic (3.30e-2)" TUSC2 "C3orf11, FUS1, PAP, PDAP2" ENSG00000114383 "Tumor suppressor 2, mitochondrial calcium regulator" O75896 3 50320027-50328251 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal suprabasal cells: 160.5;Late spermatids: 584.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" HPA030116 Approved Vesicles,Cytosol NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 1: Neurons - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 36 Cytosol Vesicles "HPA030116: " "unprognostic (1.49e-2)" "unprognostic (3.35e-2)" "unprognostic (1.38e-1)" "unprognostic (9.79e-2)" "unprognostic (1.32e-1)" "unprognostic (6.33e-2)" "unprognostic (8.33e-2)" "unprognostic (1.05e-1)" "unprognostic (3.61e-1)" "unprognostic (2.25e-2)" "unprognostic (2.93e-3)" "unprognostic (1.42e-2)" "potential prognostic favorable (4.98e-5)" "validated prognostic unfavorable (1.03e-4)" "validated prognostic unfavorable (2.53e-4)" "unprognostic (3.52e-2)" "unprognostic (1.69e-1)" "unprognostic (1.09e-1)" "unprognostic (2.14e-1)" "unprognostic (2.02e-3)" "unprognostic (2.82e-2)" "unprognostic (8.68e-2)" "unprognostic (4.90e-2)" "unprognostic (3.09e-2)" "unprognostic (3.05e-1)" "unprognostic (1.28e-1)" "unprognostic (2.09e-1)" "unprognostic (3.74e-2)" "unprognostic (1.91e-1)" "unprognostic (8.82e-2)" "unprognostic (2.31e-1)" TUSC3 "MagT2, MGC13453, MRT22, MRT7, N33, OST3A, SLC58A2" ENSG00000104723 "Tumor suppressor candidate 3" Q13454 8 15417215-15766649 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 725.5;Extravillous trophoblasts: 509.2;Gonadotrophs: 465.9;Medullary thymic epithelial cells: 451.2;Migrating cytotrophoblasts: 510.0;Pancreatic islet cells: 402.2;Syncytiotrophoblasts: 1403.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adrenal gland - Adrenal cortex cells, Liver - Hepatic stellate cells, Skeletal muscle - Endothelial cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049851, HPA049974" Approved NA NA "Cluster 20: Pituitary gland - Hormone signaling" "Cluster 23: Choroid plexus - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 14 "HPA049851: , HPA049974: " "unprognostic (1.36e-1)" "unprognostic (4.09e-3)" "unprognostic (1.68e-2)" "unprognostic (2.34e-2)" "unprognostic (6.99e-2)" "unprognostic (3.77e-1)" "unprognostic (2.03e-1)" "potential prognostic favorable (4.61e-4)" "unprognostic (2.15e-1)" "unprognostic (2.51e-1)" "unprognostic (1.30e-1)" "unprognostic (1.72e-2)" "unprognostic (3.10e-2)" "unprognostic (4.90e-3)" "unprognostic (5.11e-2)" "unprognostic (2.28e-2)" "unprognostic (8.11e-2)" "unprognostic (2.60e-1)" "unprognostic (4.50e-2)" "unprognostic (6.54e-2)" "unprognostic (1.47e-1)" "unprognostic (2.60e-3)" "unprognostic (2.12e-1)" "unprognostic (9.18e-2)" "unprognostic (1.87e-1)" "unprognostic (2.25e-1)" "unprognostic (2.23e-1)" "unprognostic (1.02e-3)" "unprognostic (2.48e-1)" "unprognostic (1.60e-3)" "unprognostic (2.32e-1)" TUT1 "FLJ21850, FLJ22267, FLJ22347, PAPD2, RBM21, TENT1, TUTase" ENSG00000149016 "Terminal uridylyl transferase 1, U6 snRNA-specific" Q9H6E5 11 62575045-62591637 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" "mRNA processing" "Nucleotidyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 3.8;Bergmann glia: 5.2;Brain excitatory neurons: 3.4;Brain inhibitory neurons: 3.4;Choroid plexus epithelial cells: 6.7;Ependymal cells: 4.1;Epididymal principal cells: 3.2;Microglia: 2.9;Oligodendrocyte progenitor cells: 2.7;Oligodendrocytes: 4.0;Other brain neurons: 4.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069055, HPA071838" Supported Nucleoplasm,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 70: Non-specific - Protein processing" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 22: Non-specific - Basic cellular functions" 25 Nucleoplasm Cytosol "HPA069055: , HPA071838: " "unprognostic (2.72e-1)" "unprognostic (2.03e-1)" "unprognostic (6.39e-2)" "unprognostic (3.52e-2)" "unprognostic (1.64e-2)" "unprognostic (1.09e-1)" "unprognostic (2.41e-1)" "unprognostic (5.24e-3)" "unprognostic (1.31e-1)" "unprognostic (8.56e-2)" "potential prognostic favorable (8.09e-4)" "unprognostic (1.46e-1)" "unprognostic (4.93e-2)" "unprognostic (2.45e-1)" "unprognostic (1.15e-2)" "unprognostic (5.10e-2)" "unprognostic (7.16e-2)" "unprognostic (3.09e-1)" "unprognostic (2.95e-1)" "unprognostic (1.07e-1)" "unprognostic (3.00e-1)" "unprognostic (2.45e-1)" "unprognostic (1.91e-1)" "unprognostic (4.19e-2)" "unprognostic (1.09e-2)" "unprognostic (7.10e-2)" "unprognostic (1.29e-1)" "unprognostic (7.14e-2)" "unprognostic (3.83e-2)" "unprognostic (2.30e-1)" "unprognostic (1.08e-2)" TUT4 "KIAA0191, PAPD3, TENT3A, ZCCHC11" ENSG00000134744 "Terminal uridylyl transferase 4" Q5TAX3 1 52408282-52553487 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "RNA-mediated gene silencing" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Corticotrophs: 707.8;Myonuclei: 736.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027412, HPA027973" Supported Supported Nucleoli,Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 67: Testis - Mixed function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 37: Non-specific - mRNA processing" "Cluster 7: Non-specific - Transcription" 4 Cytosol Nucleoli "HPA027412: , HPA027973: " "unprognostic (2.75e-1)" "unprognostic (6.68e-2)" "unprognostic (3.47e-1)" "unprognostic (8.00e-3)" "unprognostic (2.00e-1)" "unprognostic (8.41e-2)" "unprognostic (5.29e-2)" "unprognostic (2.90e-2)" "unprognostic (2.55e-3)" "unprognostic (1.01e-1)" "unprognostic (1.91e-2)" "unprognostic (4.83e-2)" "potential prognostic unfavorable (1.39e-4)" "unprognostic (1.84e-1)" "unprognostic (7.64e-2)" "unprognostic (4.25e-2)" "unprognostic (1.53e-2)" "unprognostic (2.10e-1)" "unprognostic (2.69e-2)" "potential prognostic favorable (3.51e-4)" "unprognostic (3.02e-3)" "unprognostic (2.08e-3)" "unprognostic (8.25e-2)" "unprognostic (1.52e-1)" "unprognostic (8.05e-2)" "unprognostic (2.83e-1)" "unprognostic (3.99e-1)" "unprognostic (1.71e-1)" "unprognostic (1.83e-1)" TUT7 "FLJ13409, KIAA1711, PAPD6, TENT3B, ZCCHC6" ENSG00000083223 "Terminal uridylyl transferase 7" Q5VYS8 9 86287733-86354454 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial glandular cells: 660.6;Endometrial luminal cells: 612.2;Esophageal apical cells: 473.3;monocytes: 433.2;Neutrophils: 1481.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 115.2" "Group enriched" "Detected in all" 5 "granulocytes: 115.2;monocytes: 48.2" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "HPA020615, HPA020620" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 58: Skin - Keratinization" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 24: Neutrophils - Innate immunity signal integration" Cytosol Nucleoplasm "HPA020615: , HPA020620: " "unprognostic (2.28e-2)" "unprognostic (7.84e-3)" "unprognostic (6.84e-3)" "unprognostic (1.20e-1)" "unprognostic (1.84e-2)" "unprognostic (3.84e-1)" "unprognostic (2.46e-1)" "unprognostic (2.43e-2)" "unprognostic (1.04e-1)" "unprognostic (8.05e-2)" "unprognostic (6.08e-2)" "unprognostic (5.84e-2)" "unprognostic (3.12e-2)" "unprognostic (8.22e-2)" "unprognostic (3.46e-2)" "unprognostic (2.36e-2)" "unprognostic (5.75e-2)" "unprognostic (2.62e-2)" "unprognostic (9.14e-2)" "unprognostic (5.22e-2)" "unprognostic (1.58e-2)" "unprognostic (3.56e-1)" "unprognostic (2.03e-1)" "unprognostic (1.01e-1)" "unprognostic (2.66e-2)" "unprognostic (1.78e-2)" "unprognostic (2.74e-2)" "unprognostic (3.58e-1)" "unprognostic (1.18e-1)" TVP23A "FAM18A, YDR084C" ENSG00000166676 "Trans-golgi network vesicle protein 23 homolog A" A6NH52 16 10760919-10818794 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 5.4" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 31.9;Brain excitatory neurons: 38.5;Brain inhibitory neurons: 43.7;cDC: 100.1;Epicardial cells: 36.4;Gonadotrophs: 32.1;Granulosa cells: 154.1;Oligodendrocyte progenitor cells: 39.3;Other brain neurons: 48.6;Retinal amacrine cells: 32.2" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 5.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lymphoma: 4.5" "Breast - T-cells, Colon - Enteric glia cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060582 Uncertain Approved Vesicles NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 78: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 55: Lymphoma - Immune response" "Cluster 82: Dendritic cells - Antigen presentation" 3 Vesicles "HPA060582: " "unprognostic (5.49e-2)" "unprognostic (1.34e-2)" "unprognostic (1.65e-2)" "unprognostic (2.32e-2)" "unprognostic (1.30e-1)" "unprognostic (1.23e-1)" "unprognostic (7.84e-2)" "unprognostic (1.83e-1)" "unprognostic (1.53e-1)" "unprognostic (2.29e-2)" "unprognostic (2.23e-1)" "unprognostic (3.58e-2)" "potential prognostic favorable (1.89e-4)" TVP23B "CGI-148, FAM18B, FAM18B1, YDR084C" ENSG00000171928 "Trans-golgi network vesicle protein 23 homolog B" Q9NYZ1 17 18781111-18806714 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 177.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "HPA019585, HPA065603" Uncertain Supported "Golgi apparatus" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 42: Non-specific - Unknown function" "Cluster 67: Plasma cells - Plasma cell differentiation" 23 "Golgi apparatus" "HPA019585: , HPA065603: " "unprognostic (4.34e-2)" "unprognostic (5.52e-3)" "unprognostic (2.29e-3)" "unprognostic (2.42e-1)" "unprognostic (1.20e-3)" "unprognostic (3.73e-2)" "unprognostic (1.58e-1)" "unprognostic (3.57e-1)" "unprognostic (3.24e-2)" "potential prognostic favorable (1.04e-5)" "unprognostic (3.27e-3)" "unprognostic (8.53e-2)" "unprognostic (2.17e-1)" "unprognostic (1.92e-2)" "unprognostic (6.47e-2)" "unprognostic (5.63e-2)" "unprognostic (7.50e-3)" "unprognostic (8.56e-3)" "unprognostic (8.03e-3)" "unprognostic (4.68e-2)" "unprognostic (1.36e-1)" "unprognostic (1.12e-1)" "unprognostic (3.03e-1)" "unprognostic (1.41e-1)" "unprognostic (3.72e-1)" "unprognostic (2.85e-1)" "unprognostic (3.92e-1)" "unprognostic (4.62e-1)" "unprognostic (2.12e-1)" TVP23C "FAM18B2, MGC8763" ENSG00000175106 "Trans-golgi network vesicle protein 23 homolog C" Q96ET8 17 15502264-15563595 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 21 "Astrocytes: 78.1;Bergmann glia: 67.5;Brain excitatory neurons: 83.0;Brain inhibitory neurons: 91.7;Choroid plexus epithelial cells: 182.7;Ependymal cells: 232.5;Microglia: 72.3;Oligodendrocyte progenitor cells: 118.4;Oligodendrocytes: 93.8;Other brain neurons: 92.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Skeletal muscle - Fibroblasts" "HPA019585, HPA065603" Uncertain Supported "Golgi apparatus" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 42: Non-specific - Unknown function" "Cluster 22: Non-specific - Basic cellular functions" "Golgi apparatus" "HPA019585: , HPA065603: " "unprognostic (7.03e-2)" "unprognostic (1.56e-2)" "unprognostic (1.43e-2)" "unprognostic (2.36e-2)" "unprognostic (8.10e-2)" "potential prognostic unfavorable (5.22e-4)" "unprognostic (2.53e-3)" "unprognostic (2.19e-1)" "unprognostic (2.16e-2)" "unprognostic (2.47e-1)" "unprognostic (4.93e-3)" "unprognostic (2.33e-1)" "unprognostic (6.15e-3)" "unprognostic (3.72e-2)" "unprognostic (2.02e-1)" "unprognostic (2.17e-1)" "unprognostic (2.63e-1)" "unprognostic (1.29e-1)" "unprognostic (5.59e-3)" "unprognostic (2.56e-1)" "unprognostic (1.13e-3)" "unprognostic (4.35e-2)" "unprognostic (3.53e-1)" "unprognostic (1.99e-2)" "unprognostic (4.20e-3)" "unprognostic (9.96e-2)" "unprognostic (2.08e-1)" "unprognostic (1.83e-1)" "unprognostic (3.98e-2)" TVP23C-CDRT4 FAM18B2-CDRT4 ENSG00000259024 "TVP23C-CDRT4 readthrough" 17 15436021-15563561 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gonadotrophs: 97.8;Lactotrophs: 90.2;Somatotrophs: 103.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "testis cancer: 35.1" HPA065603 Approved "Golgi apparatus" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 22: Epididymis - Mixed function" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 42: Non-specific - Unknown function" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" "Golgi apparatus" "HPA065603: " "unprognostic (5.12e-3)" "unprognostic (2.79e-1)" "unprognostic (4.62e-2)" "unprognostic (1.87e-1)" "unprognostic (1.35e-1)" "unprognostic (2.82e-2)" "unprognostic (1.58e-1)" "potential prognostic favorable (6.75e-6)" "unprognostic (1.68e-2)" "unprognostic (2.26e-1)" "unprognostic (1.58e-1)" "unprognostic (2.63e-1)" "unprognostic (1.45e-1)" "unprognostic (3.32e-2)" "unprognostic (1.74e-1)" "unprognostic (1.94e-1)" "unprognostic (1.69e-1)" "unprognostic (1.20e-1)" "unprognostic (4.00e-3)" "unprognostic (3.13e-1)" "unprognostic (3.68e-2)" "unprognostic (1.63e-1)" "unprognostic (1.12e-1)" "unprognostic (4.30e-2)" "unprognostic (2.24e-1)" "unprognostic (4.12e-2)" "unprognostic (2.07e-1)" TWF1 "A6, PTK9" ENSG00000151239 "Twinfilin actin binding protein 1" Q12792 12 43793723-43806328 "Disease related genes, Predicted intracellular proteins" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 270.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Skeletal muscle - Endothelial cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018116 Approved Supported Cytosol NA NA 25000 "Cluster 1: T-cells - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 22 Cytosol "HPA018116: " "unprognostic (3.93e-2)" "unprognostic (2.82e-1)" "unprognostic (1.38e-1)" "unprognostic (1.26e-1)" "unprognostic (6.91e-3)" "unprognostic (9.96e-2)" "unprognostic (2.11e-1)" "unprognostic (1.47e-2)" "unprognostic (3.68e-2)" "unprognostic (2.83e-1)" "unprognostic (3.08e-2)" "unprognostic (7.92e-3)" "unprognostic (2.19e-2)" "potential prognostic unfavorable (4.06e-6)" "unprognostic (8.67e-3)" "potential prognostic unfavorable (2.40e-4)" "unprognostic (8.93e-3)" "unprognostic (2.21e-2)" "unprognostic (1.27e-1)" "unprognostic (7.03e-2)" "unprognostic (3.34e-2)" "unprognostic (5.38e-3)" "unprognostic (1.20e-2)" "unprognostic (1.35e-1)" "unprognostic (7.03e-2)" "unprognostic (6.89e-2)" "unprognostic (1.52e-1)" "unprognostic (1.63e-1)" "unprognostic (3.05e-1)" "unprognostic (2.03e-1)" "unprognostic (1.88e-1)" TWF2 "A6r, A6RP, PTK9L" ENSG00000247596 "Twinfilin actin binding protein 2" Q6IBS0 3 52228612-52246788 "Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 12.3;Cardiomyocytes: 15.0;Early spermatids: 63.0;Epicardial cells: 18.2;Late spermatids: 37.6;Neutrophils: 16.2;Tuft cells: 11.5" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053874 Uncertain Uncertain "Plasma membrane" NA NA 2000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 5: Spleen - Immune response" "Cluster 14: Neurons - Synaptic function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 20 "Plasma membrane" "HPA053874: " "unprognostic (3.85e-1)" "unprognostic (1.74e-1)" "unprognostic (5.25e-2)" "unprognostic (2.31e-3)" "unprognostic (6.27e-2)" "unprognostic (2.97e-1)" "unprognostic (1.28e-2)" "unprognostic (5.57e-2)" "unprognostic (9.32e-3)" "unprognostic (3.67e-2)" "unprognostic (5.05e-2)" "unprognostic (2.71e-1)" "unprognostic (2.64e-1)" "unprognostic (1.71e-2)" "unprognostic (2.70e-2)" "unprognostic (1.06e-1)" "unprognostic (1.05e-1)" "unprognostic (3.05e-2)" "unprognostic (1.85e-1)" "unprognostic (1.70e-1)" "unprognostic (1.56e-1)" "unprognostic (1.21e-1)" "unprognostic (9.59e-2)" "unprognostic (3.76e-2)" "unprognostic (1.70e-1)" "unprognostic (1.74e-2)" "unprognostic (4.36e-2)" "unprognostic (3.53e-1)" "unprognostic (1.61e-2)" "unprognostic (1.22e-1)" "unprognostic (6.64e-2)" TWIST1 "ACS3, bHLHa38, BPES2, BPES3, CRS, CRS1, H-twist, SCS, TWIST" ENSG00000122691 "Twist family bHLH transcription factor 1" Q15672 7 19020991-19117636 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Differentiation, Myogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 25.3" "Cell type enhanced" "Detected in many" "Adipocytes: 77.7;Endometrial luminal cells: 23.2;Endometrial stromal cells: 86.0;Fibro-adipogenic progenitors: 30.7;Fibroblasts: 108.5;Mesothelial cells: 19.9;Oocytes: 23.0;Pericytes: 52.0;Smooth muscle cells: 59.3;Vascular smooth muscle cells: 22.2" "Cell type enhanced" "Detected in many" "endothelial cell: 51.4;fibroblast: 65.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 101.5" "Heart muscle - Fibroblasts" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 5 "midbrain: 6.4;spinal cord: 20.4" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 53: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 108: Fibroblasts - ECM organization" 52 "unprognostic (1.95e-1)" "unprognostic (7.59e-3)" "unprognostic (4.98e-1)" "unprognostic (1.11e-2)" "unprognostic (2.84e-2)" "unprognostic (1.83e-1)" "unprognostic (8.01e-3)" "unprognostic (1.77e-1)" "unprognostic (3.39e-2)" "unprognostic (2.12e-1)" "unprognostic (1.72e-3)" "unprognostic (4.35e-3)" "unprognostic (1.19e-3)" "unprognostic (3.17e-1)" "unprognostic (3.15e-2)" "unprognostic (2.02e-2)" "unprognostic (6.16e-2)" "unprognostic (6.33e-3)" "unprognostic (3.67e-2)" "unprognostic (2.34e-1)" "unprognostic (8.20e-2)" "potential prognostic favorable (7.43e-4)" "unprognostic (1.42e-3)" "unprognostic (1.37e-2)" "unprognostic (5.21e-2)" "unprognostic (7.13e-3)" "unprognostic (1.29e-1)" TWIST2 "bHLHa39, Dermo-1, DERMO1" ENSG00000233608 "Twist family bHLH transcription factor 2" Q8WVJ9 2 238848032-238910534 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 81.7" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 2.6;Endometrial stromal cells: 2.7;Fibroblasts: 11.0;Microglia: 24.2;Papillary tip epithelial cells: 2.6;Peritubular myoid cells: 2.2;Smooth muscle cells: 5.7" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 34.9;fibroblast: 51.9;vascular associated smooth muscle cell: 18.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 24 "eosinophil: 4.7" "Lineage enriched" "Detected in single" 47 "granulocytes: 4.7" "Cancer enhanced" "Detected in many" "Sarcoma: 12.0" "Adrenal gland - Fibroblasts, Kidney - Fibroblasts, Prostate - Fibroblasts, Spleen - Fibroblasts_1" "Low region specificity" "Detected in single" "Region enriched" "Detected in single" 7 "spinal cord: 3.6" HPA062870 Supported Nucleoplasm,Nucleoli NA NA "Cluster 75: Ovary - Mixed function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 105: Non-specific - Mixed function" 19 Nucleoplasm Nucleoli "HPA062870: " "unprognostic (2.35e-1)" "unprognostic (1.01e-2)" "unprognostic (1.10e-1)" "unprognostic (2.24e-1)" "unprognostic (1.90e-1)" "unprognostic (1.09e-2)" "unprognostic (1.50e-2)" "unprognostic (3.08e-2)" "unprognostic (4.70e-2)" "unprognostic (9.89e-2)" "unprognostic (1.43e-1)" "unprognostic (3.52e-2)" "unprognostic (1.44e-1)" "unprognostic (3.67e-3)" "unprognostic (8.55e-3)" "unprognostic (6.52e-3)" "unprognostic (1.08e-1)" "unprognostic (8.67e-2)" TWNK "C10orf2, FLJ21832, IOSCA, PEO, PEO1, TWINKLE, TWINL" ENSG00000107815 "Twinkle mtDNA helicase" Q96RR1 10 100987367-100994403 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA replication" "Helicase, Hydrolase, Isomerase" "Deafness, Disease variant, Neurodegeneration, Neuropathy, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 14.9;Erythrocyte progenitors: 19.3;Megakaryocyte-Erythroid progenitors: 15.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002532 Uncertain NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 39: Testis - Nuclear processes" "Cluster 47: Endothelial cells - Vasculature" "Cluster 52: Non-specific - Mitochondria" "Cluster 17: Non-specific - RNA processing" 8 "HPA002532: " "unprognostic (1.29e-1)" "unprognostic (4.46e-2)" "unprognostic (1.12e-2)" "unprognostic (1.23e-1)" "unprognostic (1.74e-1)" "unprognostic (4.42e-2)" "potential prognostic favorable (1.60e-4)" "unprognostic (8.36e-2)" "unprognostic (3.61e-1)" "unprognostic (5.05e-3)" "unprognostic (1.18e-2)" "unprognostic (6.31e-2)" "unprognostic (4.72e-3)" "unprognostic (3.64e-2)" "potential prognostic unfavorable (5.28e-4)" "unprognostic (2.66e-1)" "unprognostic (2.06e-2)" "unprognostic (5.26e-2)" "unprognostic (5.17e-2)" "unprognostic (3.37e-2)" "unprognostic (2.07e-1)" "unprognostic (1.46e-2)" "potential prognostic favorable (9.72e-4)" "unprognostic (2.82e-1)" "unprognostic (1.35e-1)" "unprognostic (2.10e-2)" "unprognostic (1.36e-1)" "unprognostic (2.92e-1)" "unprognostic (8.30e-2)" TWSG1 TSG ENSG00000128791 "Twisted gastrulation BMP signaling modulator 1" Q9GZX9 18 9334767-9402420 "Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Renal collecting duct principal cells: 203.8;Respiratory ionocytes: 185.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014898 Uncertain Supported Centrosome,Cytosol "Secreted - unknown location" "Developmental protein" No No 1100000 "Cluster 30: Non-specific - DNA binding" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 10 "Centrosome, Cytosol" "HPA014898: " "unprognostic (1.16e-1)" "unprognostic (2.33e-1)" "unprognostic (2.66e-1)" "unprognostic (1.37e-2)" "unprognostic (1.33e-1)" "unprognostic (7.80e-2)" "unprognostic (1.40e-3)" "potential prognostic unfavorable (6.94e-4)" "unprognostic (2.80e-1)" "unprognostic (3.27e-2)" "unprognostic (3.79e-3)" "unprognostic (1.21e-1)" "unprognostic (1.60e-2)" "unprognostic (7.14e-2)" "unprognostic (2.10e-2)" "unprognostic (7.43e-3)" "unprognostic (3.19e-2)" "unprognostic (1.49e-2)" "unprognostic (1.92e-1)" "unprognostic (3.01e-2)" "unprognostic (6.02e-3)" "unprognostic (3.10e-2)" "unprognostic (8.80e-2)" "unprognostic (3.29e-1)" "unprognostic (1.69e-1)" "unprognostic (1.25e-1)" "unprognostic (7.59e-2)" "unprognostic (4.60e-2)" "unprognostic (1.10e-1)" "unprognostic (2.51e-1)" "unprognostic (9.11e-2)" TXK "BTKL, PSCTK5, PTK4, RLK, TKL" ENSG00000074966 "TXK tyrosine kinase" P42681 4 48066393-48134250 "Enzymes, Predicted intracellular proteins" "Adaptive immunity, Immunity, Transcription, Transcription regulation" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 7.9;lymphoid tissue: 14.4" "Cell type enhanced" "Detected in many" "Hematopoietic stem cells: 198.5;Innate lymphoid cells: 490.6;Megakaryocyte progenitors: 141.0;Megakaryocyte-Erythroid progenitors: 132.9;NK-cells: 792.4;Retinal ganglion cells: 154.5;T-cells: 215.8;Thymocytes: 468.4" "Cell type enhanced" "Detected in many" "leukocyte: 251.1;lower rhombic lip: 85.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "NK-cell: 118.7" "Group enriched" "Detected in many" 18 "NK-cells: 118.7;T-cells: 49.8" "Low cancer specificity" "Detected in some" "Adipose visceral - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Prostate - T-cells, Spleen - NK-cells (Spleen)" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA078636 Supported "Nucleoplasm,Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 18 "Nucleoplasm, Cytosol" "Nucleoli, Plasma membrane" "HPA078636: " "unprognostic (2.83e-1)" "unprognostic (6.19e-2)" "unprognostic (5.35e-2)" "unprognostic (5.38e-2)" "unprognostic (2.44e-1)" "unprognostic (1.86e-2)" "unprognostic (4.33e-3)" "unprognostic (3.68e-1)" "unprognostic (3.32e-1)" "unprognostic (3.45e-2)" "unprognostic (9.78e-2)" "unprognostic (5.18e-3)" "unprognostic (2.34e-2)" "unprognostic (1.09e-1)" TXLNA DKFZp451J0118 ENSG00000084652 "Taxilin alpha" P40222 1 32179675-32198285 "Cancer-related genes, Predicted intracellular proteins" Exocytosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045383, HPA072477" Supported Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 76: Non-specific - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 132 Cytosol "Nucleoplasm, Centrosome" "HPA045383: , HPA072477: " "unprognostic (7.05e-3)" "unprognostic (2.00e-1)" "unprognostic (1.79e-1)" "unprognostic (1.88e-1)" "unprognostic (1.57e-1)" "unprognostic (1.10e-2)" "unprognostic (3.40e-1)" "unprognostic (2.58e-1)" "unprognostic (1.14e-2)" "unprognostic (1.10e-2)" "unprognostic (5.53e-2)" "unprognostic (1.02e-1)" "unprognostic (3.41e-1)" "potential prognostic unfavorable (3.57e-7)" "unprognostic (3.69e-3)" "unprognostic (1.92e-1)" "unprognostic (2.95e-2)" "unprognostic (1.51e-1)" "unprognostic (2.84e-2)" "unprognostic (2.01e-2)" "unprognostic (4.12e-2)" "unprognostic (9.49e-3)" "unprognostic (8.07e-2)" "unprognostic (6.83e-3)" "unprognostic (3.18e-1)" "unprognostic (4.58e-2)" "unprognostic (1.20e-1)" "unprognostic (4.21e-2)" "unprognostic (1.38e-1)" "unprognostic (6.53e-2)" "unprognostic (1.23e-1)" TXLNB "C6orf198, dJ522B19.2, DKFZp451A175, MDP77" ENSG00000164440 "Taxilin beta" Q8N3L3 6 139240061-139291998 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 22 "heart muscle: 76.7;skeletal muscle: 280.9;tongue: 176.6" "Group enriched" "Detected in some" 5 "Cardiomyocytes: 53.8;Late spermatids: 56.9;Myonuclei: 194.5;Thymic myoid cells: 131.9" "Cell type enhanced" "Detected in many" "fibroblast: 9.8" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 3.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.9" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in some" "lymphoma: 4.4" "Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA030401, HPA030402, HPA030403" Enhanced NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 39: Astrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 80 "HPA030401: , HPA030402: , HPA030403: " "unprognostic (1.57e-1)" "unprognostic (5.52e-2)" "unprognostic (1.95e-2)" "potential prognostic unfavorable (7.21e-5)" "unprognostic (1.21e-1)" "unprognostic (8.01e-3)" "unprognostic (1.22e-1)" "unprognostic (1.11e-1)" "unprognostic (5.96e-2)" "unprognostic (7.18e-3)" TXLNG "CXorf15, FIAT, FLJ11209, LSR5, MGC126621, MGC126625, TXLNGX" ENSG00000086712 "Taxilin gamma" Q9NUQ3 X 16786432-16844519 "Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000297, HPA000841" Approved Approved Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 75: Ovary - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 36: Non-specific - mRNA processing" "Cluster 103: Non-specific - Basic cellular processes" 13 Cytosol "HPA000297: , HPA000841: " "unprognostic (1.15e-1)" "unprognostic (1.13e-1)" "unprognostic (9.29e-2)" "potential prognostic unfavorable (9.49e-5)" "unprognostic (6.78e-2)" "unprognostic (6.00e-2)" "unprognostic (9.70e-2)" "unprognostic (1.86e-1)" "unprognostic (1.72e-1)" "unprognostic (3.14e-3)" "potential prognostic favorable (2.87e-5)" "unprognostic (6.35e-3)" "unprognostic (2.40e-2)" "unprognostic (1.12e-2)" "potential prognostic unfavorable (9.80e-4)" "unprognostic (1.84e-1)" "unprognostic (1.40e-2)" "unprognostic (6.35e-2)" "unprognostic (2.44e-2)" "unprognostic (1.23e-1)" "unprognostic (1.89e-1)" "unprognostic (1.94e-1)" "unprognostic (1.01e-1)" "unprognostic (7.52e-2)" "unprognostic (1.32e-2)" "unprognostic (1.45e-1)" "unprognostic (1.87e-1)" "unprognostic (5.97e-2)" "unprognostic (3.41e-1)" "unprognostic (4.13e-2)" "unprognostic (1.03e-1)" TXN "TRX, Trx80" ENSG00000136810 Thioredoxin P10599 9 110243810-110256507 "Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Electron transport, Transcription, Transcription regulation, Transport" Activator Allergen "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 1237.8" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 9041.3;Esophageal basal cells: 4687.0;Esophageal suprabasal cells: 15115.7;Gastric progenitor cells: 5418.9;Suprabasal keratinocytes: 3556.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 1646.2;granulocytes: 1359.5" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Not detected" "Not detected" "CAB008678, HPA047478, HPA055752" Enhanced Enhanced Nucleoplasm,Cytosol "Intracellular and membrane" Transport NA NA 33000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 85: Squamous epithelial cells - Keratinization" 61 "Nucleoplasm, Cytosol" "CAB008678: , HPA047478: , HPA055752: " "unprognostic (1.97e-1)" "unprognostic (2.02e-3)" "unprognostic (1.36e-1)" "unprognostic (1.50e-1)" "unprognostic (2.40e-1)" "unprognostic (1.87e-1)" "unprognostic (5.70e-3)" "unprognostic (2.69e-2)" "unprognostic (2.49e-2)" "unprognostic (2.47e-2)" "unprognostic (3.08e-2)" "unprognostic (9.09e-2)" "unprognostic (1.79e-3)" "unprognostic (3.58e-3)" "potential prognostic unfavorable (2.88e-4)" "potential prognostic unfavorable (1.74e-4)" "unprognostic (2.44e-1)" "unprognostic (2.96e-1)" "unprognostic (1.30e-1)" "unprognostic (2.08e-2)" "unprognostic (1.22e-1)" "unprognostic (3.50e-3)" "unprognostic (3.09e-1)" "unprognostic (1.17e-1)" "unprognostic (3.92e-1)" "unprognostic (8.76e-2)" "unprognostic (1.11e-1)" "unprognostic (6.89e-2)" "unprognostic (1.81e-1)" "unprognostic (6.90e-2)" "unprognostic (3.67e-3)" TXN2 MT-TRX ENSG00000100348 "Thioredoxin 2" Q99757 22 36467046-36481640 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Transport" "Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal suprabasal cells: 293.5;Extravillous trophoblasts: 341.2;Oocytes: 331.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000994, CAB008681" Approved Enhanced Mitochondria No No 3600000 "Cluster 13: Non-specific - Mitochondria" "Cluster 76: Non-specific - Metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 97: Non-specific - Cellular respiration" 72 Mitochondria "CAB008681: , HPA000994: " "unprognostic (1.27e-1)" "unprognostic (1.09e-1)" "unprognostic (3.02e-1)" "unprognostic (2.52e-1)" "potential prognostic favorable (5.57e-4)" "unprognostic (7.06e-2)" "unprognostic (1.60e-1)" "unprognostic (3.21e-1)" "unprognostic (1.38e-2)" "unprognostic (1.27e-2)" "unprognostic (2.88e-3)" "unprognostic (1.29e-1)" "potential prognostic favorable (1.98e-5)" "unprognostic (3.26e-3)" "unprognostic (7.58e-3)" "unprognostic (6.95e-2)" "unprognostic (2.91e-1)" "unprognostic (3.52e-3)" "unprognostic (8.85e-3)" "unprognostic (3.91e-2)" "unprognostic (3.09e-1)" "unprognostic (1.83e-1)" "unprognostic (1.52e-1)" "potential prognostic favorable (8.85e-4)" "unprognostic (7.35e-3)" "unprognostic (5.69e-2)" "unprognostic (2.07e-1)" "unprognostic (5.34e-2)" "unprognostic (1.95e-1)" "unprognostic (1.28e-1)" "unprognostic (7.93e-2)" TXNDC11 EFP1 ENSG00000153066 "Thioredoxin domain containing 11" Q6PKC3 16 11679083-11742857 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 308.7;Plasma cells: 588.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 119.2;Myeloma: 175.3" "Breast - Plasma cells, Prostate - Prostate glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041174, HPA041390" Supported Supported "Plasma membrane,Cytosol" No No "Cluster 45: Eosinophils - Unknown function" "Cluster 17: Intestine - Digestion" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 44: Plasma cells - Antibody production & secretion" 8 "Plasma membrane, Cytosol" "HPA041174: , HPA041390: " "unprognostic (6.23e-1)" "unprognostic (9.28e-2)" "unprognostic (1.75e-1)" "unprognostic (1.64e-2)" "unprognostic (6.02e-2)" "unprognostic (1.86e-1)" "unprognostic (1.01e-1)" "unprognostic (3.73e-2)" "unprognostic (4.05e-2)" "unprognostic (6.48e-2)" "potential prognostic favorable (1.24e-6)" "unprognostic (2.45e-1)" "unprognostic (1.04e-1)" "unprognostic (2.22e-1)" "unprognostic (2.39e-1)" "unprognostic (1.02e-3)" "unprognostic (2.69e-2)" "potential prognostic unfavorable (6.48e-4)" "unprognostic (2.06e-1)" "unprognostic (1.86e-1)" "unprognostic (2.41e-1)" "unprognostic (6.37e-2)" "unprognostic (3.28e-2)" "unprognostic (3.17e-1)" "unprognostic (6.63e-2)" "unprognostic (9.27e-2)" "unprognostic (2.03e-1)" "unprognostic (2.49e-2)" "unprognostic (1.88e-2)" "unprognostic (1.83e-1)" "unprognostic (3.12e-2)" TXNDC12 "AGR1, ERP18, ERP19, hAG-1, PDIA16, TLP19" ENSG00000117862 "Thioredoxin domain containing 12" O95881 1 52020131-52055191 "Enzymes, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" Enzyme NA NA 120000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 22: Epididymis - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 15: Kidney cancer - Membrane components" "Cluster 15: Non-specific - Protein processing" 12 "unprognostic (6.94e-2)" "unprognostic (1.25e-1)" "unprognostic (7.82e-2)" "unprognostic (3.26e-2)" "potential prognostic favorable (9.68e-4)" "unprognostic (6.58e-2)" "unprognostic (1.80e-1)" "unprognostic (2.59e-3)" "potential prognostic unfavorable (2.07e-4)" "unprognostic (1.07e-2)" "unprognostic (4.05e-3)" "unprognostic (8.87e-2)" "unprognostic (1.68e-3)" "validated prognostic unfavorable (4.39e-8)" "validated prognostic unfavorable (6.90e-4)" "unprognostic (3.53e-2)" "unprognostic (1.90e-2)" "unprognostic (7.91e-2)" "unprognostic (1.92e-1)" "unprognostic (3.05e-1)" "unprognostic (1.06e-1)" "unprognostic (1.29e-3)" "unprognostic (1.27e-1)" "unprognostic (3.57e-1)" "unprognostic (1.14e-2)" "unprognostic (1.47e-1)" "unprognostic (7.39e-2)" "unprognostic (4.18e-2)" "unprognostic (2.24e-1)" "unprognostic (1.31e-2)" "unprognostic (3.55e-1)" TXNDC15 "2310047H23Rik, C5orf14, FLJ22625" ENSG00000113621 "Thioredoxin domain containing 15" Q96J42 5 134874371-134901635 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Meckel syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 283.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015483 Approved Approved "Golgi apparatus" NA NA 1400000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 67: Plasma cells - Plasma cell differentiation" 1 "Golgi apparatus" "HPA015483: " "unprognostic (2.22e-1)" "unprognostic (5.67e-2)" "unprognostic (2.25e-1)" "unprognostic (5.02e-2)" "unprognostic (1.32e-1)" "unprognostic (7.21e-2)" "unprognostic (3.74e-3)" "unprognostic (2.31e-3)" "unprognostic (2.68e-1)" "unprognostic (2.37e-3)" "potential prognostic favorable (1.88e-7)" "unprognostic (2.20e-1)" "unprognostic (6.85e-2)" "unprognostic (4.20e-2)" "unprognostic (3.18e-2)" "unprognostic (2.42e-3)" "unprognostic (2.11e-1)" "unprognostic (3.14e-3)" "unprognostic (2.66e-1)" "unprognostic (1.45e-1)" "potential prognostic unfavorable (3.94e-4)" "unprognostic (3.45e-2)" "unprognostic (2.80e-1)" "unprognostic (1.23e-1)" "unprognostic (9.84e-2)" "unprognostic (6.66e-2)" "unprognostic (1.50e-1)" "unprognostic (1.09e-1)" "unprognostic (6.82e-2)" "unprognostic (8.74e-2)" "unprognostic (1.19e-1)" TXNDC16 KIAA1344 ENSG00000087301 "Thioredoxin domain containing 16" Q9P2K2 14 52430596-52552522 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial luminal cells: 350.1;Prostatic glandular cells: 208.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 26.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002543 Approved Approved Mitochondria "Secreted to blood" "No annotated function" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 61: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 5 Mitochondria "HPA002543: " "unprognostic (2.31e-1)" "unprognostic (2.02e-1)" "potential prognostic unfavorable (8.99e-5)" "unprognostic (1.02e-1)" "unprognostic (9.45e-2)" "unprognostic (1.72e-1)" "unprognostic (1.83e-1)" "unprognostic (1.84e-2)" "unprognostic (9.19e-2)" "unprognostic (3.84e-1)" "validated prognostic favorable (1.03e-8)" "validated prognostic favorable (1.50e-4)" "unprognostic (2.05e-1)" "unprognostic (1.45e-1)" "unprognostic (1.00e-2)" "unprognostic (5.44e-2)" "unprognostic (3.22e-1)" "unprognostic (7.56e-2)" "unprognostic (1.75e-2)" "unprognostic (4.92e-1)" "unprognostic (2.74e-1)" "unprognostic (2.36e-2)" "unprognostic (1.99e-3)" "unprognostic (9.16e-2)" "unprognostic (5.68e-2)" "unprognostic (1.43e-1)" "unprognostic (1.20e-2)" "unprognostic (3.65e-2)" "unprognostic (1.50e-1)" "unprognostic (2.42e-2)" "unprognostic (8.21e-2)" TXNDC17 "MGC14353, TRP14, TXNL5" ENSG00000129235 "Thioredoxin domain containing 17" Q9BRA2 17 6640985-6644541 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 178.4" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 3676.8;Esophageal basal cells: 1239.2;Esophageal suprabasal cells: 1800.3;Parietal cells: 859.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022931 Approved NA NA 620000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 42: Non-specific - Unknown function" "Cluster 85: Squamous epithelial cells - Keratinization" 7 "HPA022931: " "unprognostic (8.55e-3)" "unprognostic (1.49e-2)" "unprognostic (8.91e-3)" "unprognostic (6.44e-2)" "unprognostic (8.94e-2)" "unprognostic (3.64e-2)" "unprognostic (1.18e-1)" "unprognostic (3.66e-2)" "unprognostic (3.83e-2)" "potential prognostic unfavorable (3.06e-4)" "validated prognostic unfavorable (3.83e-4)" "validated prognostic unfavorable (3.73e-6)" "unprognostic (7.52e-2)" "unprognostic (6.59e-2)" "unprognostic (8.96e-2)" "unprognostic (1.47e-1)" "unprognostic (6.49e-2)" "unprognostic (2.16e-1)" "unprognostic (2.65e-2)" "unprognostic (1.92e-3)" "unprognostic (7.94e-2)" "unprognostic (1.00e-3)" "unprognostic (1.50e-1)" "unprognostic (1.86e-1)" "unprognostic (2.53e-1)" "unprognostic (1.13e-1)" "unprognostic (1.20e-1)" "unprognostic (2.73e-1)" "unprognostic (3.47e-1)" "unprognostic (1.24e-1)" "unprognostic (6.57e-2)" TXNDC2 SPTRX1 ENSG00000168454 "Thioredoxin domain containing 2" Q86VQ3 18 9885766-9889275 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 313 "testis: 98.0" "Cell type enhanced" "Detected in some" "Early spermatids: 393.2;Late primary spermatocytes: 72.3;Late spermatids: 154.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB016414, HPA018817" Enhanced NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 72: Neuronal - Signal transduction" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 1 "CAB016414: , HPA018817: " "unprognostic (6.51e-3)" TXNDC5 "EndoPDI, ERp46, FLJ21353, FLJ90810, Hcc-2, MGC3178, PDIA15" ENSG00000239264 "Thioredoxin domain containing 5" Q8NBS9 6 7881517-7910788 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Isomerase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Choroid plexus epithelial cells: 38.2;Plasma cells: 131.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 14 "memory B-cell: 13.0;naive B-cell: 6.9;plasmacytoid DC: 26.8" "Group enriched" "Detected in many" 21 "B-cells: 13.0;dendritic cells: 26.8" "Cancer enriched" "Detected in all" 6 "Myeloma: 2947.3" "Breast - Plasma cells, Minor Salivary Gland - Plasma cells, Stomach - Plasma cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034677, HPA034678" Enhanced Approved "Endoplasmic reticulum" "Intracellular and membrane" Enzyme NA NA 5300000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 60: Stomach - Digestion" "Cluster 44: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 67: Plasma cells - Plasma cell differentiation" 16 "Endoplasmic reticulum" "HPA034677: , HPA034678: " "unprognostic (4.70e-2)" "unprognostic (1.52e-1)" "unprognostic (1.11e-1)" "unprognostic (1.83e-3)" "unprognostic (1.64e-2)" "unprognostic (1.27e-1)" "unprognostic (1.20e-1)" "unprognostic (2.78e-1)" "unprognostic (2.14e-2)" "unprognostic (1.15e-1)" "unprognostic (7.23e-3)" "unprognostic (4.03e-2)" "unprognostic (7.87e-3)" "unprognostic (7.13e-3)" "unprognostic (5.98e-3)" "potential prognostic favorable (8.07e-4)" "unprognostic (4.99e-2)" "unprognostic (2.99e-3)" "unprognostic (3.90e-1)" "unprognostic (1.04e-1)" "unprognostic (5.01e-2)" "unprognostic (1.04e-1)" "unprognostic (2.05e-2)" "unprognostic (1.53e-1)" "unprognostic (1.33e-1)" "unprognostic (1.57e-1)" "unprognostic (2.81e-3)" "unprognostic (4.47e-2)" "unprognostic (2.83e-2)" "unprognostic (1.06e-2)" "unprognostic (5.14e-2)" TXNDC8 "bA427L11.2, SPTRX-3, TRX6" ENSG00000204193 "Thioredoxin domain containing 8" Q6A555 9 110303476-110337884 "Cancer-related genes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 116 "testis: 17.5" "Cell type enhanced" "Detected in some" "Early spermatids: 473.2;Late primary spermatocytes: 227.1;Late spermatids: 918.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" TXNDC9 APACD ENSG00000115514 "Thioredoxin domain containing 9" O14530 2 99318982-99340702 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 143.1;Esophageal apical cells: 148.6;Late primary spermatocytes: 149.1;Oocytes: 142.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031844, HPA031845, HPA031846" Approved Enhanced Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 76: Non-specific - Metabolism" "Cluster 27: Non-specific - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 56 Cytosol "HPA031844: , HPA031845: , HPA031846: " "unprognostic (3.75e-2)" "potential prognostic unfavorable (7.44e-4)" "unprognostic (1.93e-1)" "unprognostic (1.73e-1)" "unprognostic (5.92e-2)" "unprognostic (8.86e-3)" "unprognostic (1.77e-1)" "unprognostic (1.16e-1)" "potential prognostic unfavorable (1.42e-4)" "potential prognostic unfavorable (7.45e-4)" "potential prognostic favorable (4.32e-4)" "unprognostic (1.46e-1)" "unprognostic (4.01e-1)" "potential prognostic unfavorable (4.22e-8)" "unprognostic (3.42e-2)" "unprognostic (2.54e-3)" "unprognostic (3.95e-1)" "unprognostic (3.91e-1)" "unprognostic (3.16e-1)" "unprognostic (8.82e-2)" "unprognostic (2.05e-3)" "unprognostic (2.26e-2)" "potential prognostic unfavorable (3.06e-5)" "unprognostic (1.54e-1)" "unprognostic (5.14e-3)" "unprognostic (3.11e-2)" "unprognostic (5.77e-2)" "unprognostic (1.21e-3)" "unprognostic (1.54e-1)" "unprognostic (5.75e-2)" "unprognostic (2.25e-1)" TXNIP "ARRDC6, EST01027, HHCPA78, THIF, VDUP1" ENSG00000265972 "Thioredoxin interacting protein" Q9H3M7 1 145992435-145996579 "Cancer-related genes, Predicted intracellular proteins, Transporters" "Cell cycle, Transcription, Transcription regulation" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 1925.8;Innate lymphoid cells: 1613.7;Neutrophils: 5229.1;Thymic myoid cells: 2088.4" "Cell type enhanced" "Detected in many" "leukocyte: 699.6;pericyte: 912.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031085, HPA053694" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 38 "Plasma membrane" Cytosol "HPA031085: , HPA053694: " "unprognostic (7.43e-3)" "unprognostic (2.70e-1)" "unprognostic (5.09e-2)" "unprognostic (8.67e-2)" "unprognostic (2.91e-1)" "potential prognostic unfavorable (2.14e-4)" "unprognostic (5.01e-3)" "unprognostic (1.32e-1)" "unprognostic (2.65e-1)" "potential prognostic favorable (6.87e-7)" "unprognostic (1.53e-2)" "unprognostic (5.03e-1)" "unprognostic (2.40e-2)" "unprognostic (1.56e-3)" "unprognostic (3.34e-1)" "unprognostic (2.00e-1)" "unprognostic (1.32e-2)" "unprognostic (2.10e-1)" "unprognostic (3.52e-2)" "unprognostic (2.61e-2)" "unprognostic (1.23e-1)" "unprognostic (1.47e-2)" "unprognostic (1.02e-1)" "unprognostic (2.09e-1)" "unprognostic (1.77e-2)" "unprognostic (1.52e-1)" "unprognostic (2.00e-1)" "unprognostic (1.21e-1)" TXNL1 "TRP32, Txl, TXNL" ENSG00000091164 "Thioredoxin like 1" O43396 18 56597209-56651600 "Plasma proteins, Predicted intracellular proteins" "Electron transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 611.8;Syncytiotrophoblasts: 476.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002828, HPA002829, CAB016446" Supported Supported Enhanced Cytosol NA Yes 2400000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 16 Cytosol "CAB016446: , HPA002828: , HPA002829: " "unprognostic (1.15e-1)" "unprognostic (1.98e-1)" "unprognostic (3.78e-1)" "unprognostic (4.11e-2)" "potential prognostic favorable (4.73e-4)" "unprognostic (3.61e-1)" "unprognostic (2.51e-2)" "unprognostic (7.61e-2)" "unprognostic (1.06e-1)" "unprognostic (1.66e-1)" "unprognostic (5.38e-3)" "unprognostic (1.70e-1)" "unprognostic (1.27e-3)" "potential prognostic unfavorable (8.01e-9)" "unprognostic (3.09e-3)" "unprognostic (7.12e-3)" "unprognostic (5.02e-2)" "unprognostic (5.26e-2)" "unprognostic (1.63e-1)" "unprognostic (4.69e-3)" "unprognostic (3.91e-2)" "unprognostic (8.05e-2)" "unprognostic (2.19e-1)" "unprognostic (1.72e-1)" "unprognostic (2.90e-1)" "potential prognostic unfavorable (6.82e-4)" "unprognostic (1.47e-1)" "unprognostic (4.46e-1)" "unprognostic (2.12e-1)" "unprognostic (3.57e-1)" "unprognostic (7.90e-2)" TXNL4A "DIB1, DIM1, HsT161, SNRNP15, TXNL4, U5-15kD" ENSG00000141759 "Thioredoxin like 4A" P83876 18 79970813-80033949 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, mRNA processing, mRNA splicing" Deafness "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 323.1;Megakaryocytes: 327.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076100 Supported Nucleoplasm,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 97: Non-specific - Cellular respiration" 51 Nucleoplasm Cytosol "HPA076100: " "unprognostic (2.05e-2)" "unprognostic (6.29e-2)" "unprognostic (4.45e-2)" "unprognostic (3.54e-2)" "unprognostic (5.42e-3)" "unprognostic (1.18e-1)" "unprognostic (1.03e-3)" "unprognostic (1.05e-1)" "unprognostic (1.85e-1)" "unprognostic (6.55e-2)" "unprognostic (1.85e-3)" "unprognostic (1.84e-1)" "potential prognostic favorable (4.51e-4)" "validated prognostic unfavorable (1.77e-5)" "validated prognostic unfavorable (2.77e-6)" "unprognostic (9.10e-2)" "unprognostic (2.11e-1)" "unprognostic (3.55e-2)" "unprognostic (1.64e-2)" "unprognostic (9.04e-3)" "unprognostic (1.91e-1)" "unprognostic (2.53e-2)" "unprognostic (3.34e-2)" "unprognostic (1.14e-1)" "unprognostic (1.53e-1)" "unprognostic (1.85e-1)" "unprognostic (9.73e-2)" "unprognostic (1.75e-1)" "unprognostic (2.56e-1)" "unprognostic (1.92e-1)" "unprognostic (1.87e-2)" TXNL4B "Dim2, DLP, FLJ20511" ENSG00000140830 "Thioredoxin like 4B" Q9NX01 16 72044289-72094431 "Essential proteins, Predicted intracellular proteins" "Cell cycle, mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Cardiomyocytes: 490.6;Epicardial cells: 641.3;Mesothelial cells: 283.2;Platelets: 324.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065865 Supported Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 75: Ovary - Mixed function" "Cluster 55: Non-specific - Transcription" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 20 Nucleoplasm Cytosol "HPA065865: " "unprognostic (5.09e-2)" "unprognostic (1.11e-1)" "unprognostic (6.68e-2)" "unprognostic (5.34e-2)" "unprognostic (7.32e-2)" "unprognostic (5.30e-2)" "unprognostic (1.64e-1)" "unprognostic (1.98e-1)" "unprognostic (2.85e-2)" "unprognostic (6.79e-2)" "unprognostic (1.43e-2)" "unprognostic (1.58e-1)" "unprognostic (2.18e-1)" "unprognostic (1.23e-2)" "unprognostic (1.17e-1)" "unprognostic (1.91e-1)" "unprognostic (8.55e-3)" "unprognostic (1.04e-1)" "unprognostic (4.32e-2)" "unprognostic (2.37e-2)" "unprognostic (2.24e-2)" "unprognostic (2.75e-2)" "unprognostic (1.84e-2)" "unprognostic (7.22e-2)" "unprognostic (4.92e-2)" "unprognostic (1.26e-2)" "unprognostic (4.24e-2)" "unprognostic (5.39e-2)" "unprognostic (1.02e-1)" "unprognostic (1.06e-2)" "unprognostic (5.57e-2)" TXNRD1 "GRIM-12, Trxr1, TXNR" ENSG00000198431 "Thioredoxin reductase 1" Q16881 12 104215779-104350307 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Electron transport, Transport" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epididymal basal cells: 806.1;Ocular epithelial cells: 922.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Smooth muscle cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001395, CAB004607, CAB015834, HPA043871" Approved Supported Nucleoplasm NA NA 3000000 "Cluster 35: Neutrophils - Protein binding" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 7: Liver cancer - Metabolism" "Cluster 100: Stratified epithelial cells - Barrier functions" 9 Nucleoplasm "CAB004607: , CAB015834: , HPA001395: , HPA043871: " "unprognostic (3.36e-1)" "unprognostic (2.63e-3)" "unprognostic (2.09e-2)" "unprognostic (1.14e-1)" "unprognostic (1.41e-2)" "unprognostic (5.96e-2)" "unprognostic (1.95e-1)" "unprognostic (1.71e-1)" "unprognostic (1.98e-2)" "unprognostic (3.69e-3)" "potential prognostic favorable (2.34e-4)" "unprognostic (7.08e-2)" "potential prognostic unfavorable (3.04e-7)" "potential prognostic unfavorable (1.74e-5)" "unprognostic (2.00e-3)" "potential prognostic unfavorable (7.64e-4)" "unprognostic (3.56e-2)" "unprognostic (2.22e-2)" "unprognostic (1.45e-2)" "unprognostic (1.88e-1)" "unprognostic (1.15e-2)" "unprognostic (8.52e-2)" "unprognostic (5.83e-2)" "unprognostic (6.11e-2)" "unprognostic (1.84e-1)" "unprognostic (5.13e-3)" "unprognostic (1.99e-1)" "unprognostic (9.68e-2)" "unprognostic (8.17e-2)" "unprognostic (1.63e-3)" "unprognostic (2.60e-1)" TXNRD2 "SELZ, TR, TR3, TRXR2" ENSG00000184470 "Thioredoxin reductase 2" Q9NNW7 22 19875517-19941820 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Prostatic glandular cells: 94.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002007, HPA003323" Supported Approved Mitochondria,Cytosol NA NA 450000 "Cluster 25: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 5: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 4 "Mitochondria, Cytosol" "CAB002007: , HPA003323: " "unprognostic (2.45e-3)" "unprognostic (4.27e-2)" "unprognostic (1.91e-1)" "unprognostic (1.02e-2)" "unprognostic (2.69e-2)" "unprognostic (6.31e-3)" "unprognostic (5.27e-2)" "unprognostic (1.05e-1)" "unprognostic (2.01e-2)" "unprognostic (5.36e-2)" "potential prognostic favorable (1.98e-4)" "unprognostic (1.04e-1)" "potential prognostic favorable (3.07e-6)" "unprognostic (3.23e-1)" "unprognostic (1.07e-1)" "unprognostic (2.65e-1)" "unprognostic (2.83e-1)" "unprognostic (3.04e-2)" "unprognostic (2.22e-1)" "unprognostic (1.16e-1)" "unprognostic (9.67e-2)" "unprognostic (5.88e-2)" "unprognostic (1.26e-3)" "unprognostic (6.64e-2)" "unprognostic (5.30e-2)" "unprognostic (2.08e-2)" "unprognostic (7.06e-2)" "unprognostic (2.51e-1)" "unprognostic (1.83e-1)" "unprognostic (7.04e-2)" "unprognostic (1.49e-1)" TXNRD3 "TGR, TR2, TR2IT1, TRXR3, TXNRD3IT1, TXNRD3NB, TXNRD3NT1" ENSG00000197763 "Thioredoxin reductase 3" Q86VQ6 3 126571779-126655124 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Differentiation, Electron transport, Spermatogenesis, Transport" "Developmental protein, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 19.1" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 115.6;Myonuclei: 88.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD4 T-cell: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020802, HPA036109" Uncertain Enhanced Nucleoplasm,Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 57: Testis - Spermatogenesis" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 27: Breast cancer - Unknown function" "Cluster 3: Early primary spermatocytes - Early meiosis" 9 Nucleoplasm Cytosol "CAB020802: , HPA036109: " "unprognostic (1.50e-1)" "unprognostic (2.67e-1)" "unprognostic (2.17e-1)" "unprognostic (8.59e-2)" "unprognostic (2.35e-1)" "unprognostic (1.93e-1)" "unprognostic (1.50e-2)" "unprognostic (1.02e-1)" "unprognostic (1.07e-2)" "potential prognostic favorable (5.54e-4)" "unprognostic (1.67e-1)" "unprognostic (3.07e-1)" "unprognostic (1.82e-1)" "unprognostic (6.09e-2)" "unprognostic (1.43e-1)" "unprognostic (3.68e-2)" "unprognostic (7.69e-2)" "unprognostic (1.82e-1)" "unprognostic (1.31e-1)" "unprognostic (2.91e-1)" "unprognostic (1.63e-3)" "unprognostic (9.74e-2)" "unprognostic (6.39e-2)" "unprognostic (2.60e-2)" "unprognostic (7.36e-3)" "unprognostic (4.15e-2)" "unprognostic (1.38e-1)" "unprognostic (2.46e-1)" "unprognostic (1.26e-2)" "unprognostic (4.09e-2)" TYK2 JTK1 ENSG00000105397 "Tyrosine kinase 2" P29597 19 10350533-10380608 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Neutrophils: 141.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005157 Uncertain Approved Cytosol NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 28 Cytosol "HPA005157: " "unprognostic (2.25e-1)" "unprognostic (2.70e-2)" "unprognostic (3.15e-2)" "potential prognostic favorable (5.22e-5)" "unprognostic (1.49e-1)" "unprognostic (3.40e-1)" "unprognostic (7.77e-2)" "unprognostic (1.07e-1)" "unprognostic (2.48e-3)" "unprognostic (1.35e-1)" "potential prognostic unfavorable (5.44e-11)" "unprognostic (1.03e-1)" "unprognostic (1.94e-2)" "unprognostic (6.71e-2)" "unprognostic (1.13e-1)" "unprognostic (2.53e-1)" "unprognostic (1.28e-1)" "unprognostic (1.31e-2)" "unprognostic (2.30e-2)" "unprognostic (6.73e-3)" "unprognostic (2.93e-2)" "potential prognostic favorable (1.74e-4)" "unprognostic (4.62e-3)" "unprognostic (5.63e-2)" "unprognostic (2.42e-1)" "unprognostic (2.68e-2)" "unprognostic (1.62e-1)" "unprognostic (6.70e-2)" "unprognostic (7.56e-2)" "unprognostic (2.36e-1)" "unprognostic (1.87e-2)" TYMP "ECGF1, MNGIE" ENSG00000025708 "Thymidine phosphorylase" P19971 22 50525752-50530032 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Angiogenesis, Chemotaxis, Differentiation" "Developmental protein, Glycosyltransferase, Growth factor, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets, Neuropathy, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "cDC: 355.1;Esophageal apical cells: 220.7;Esophageal suprabasal cells: 240.4;Extravillous trophoblasts: 378.0;Macrophages: 281.0;monocytes: 586.6;Neutrophils: 409.7" "Group enriched" "Detected in many" 4 "central nervous system macrophage: 40.7;ependymal cell: 61.8;leukocyte: 74.7" "Cancer enhanced" "Detected in all" "Head and Neck Squamous Cell Carcinoma (TCGA): 543.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 137.0;eosinophil: 75.1;intermediate monocyte: 98.9;myeloid DC: 39.6;neutrophil: 115.9;non-classical monocyte: 77.6" "Group enriched" "Detected in all" 10 "dendritic cells: 39.6;granulocytes: 115.9;monocytes: 137.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 86.4" "Not detected" "Not detected" "HPA000530, HPA001072, CAB002518" Enhanced Approved "Nuclear bodies,Golgi apparatus,Cytosol" NA NA 10000000 "Cluster 25: Non-specific - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 24 "Nuclear bodies, Golgi apparatus" Cytosol "CAB002518: , HPA000530: , HPA001072: " "unprognostic (2.42e-2)" "unprognostic (1.91e-2)" "unprognostic (2.41e-1)" "unprognostic (9.74e-2)" "unprognostic (3.82e-1)" "unprognostic (2.15e-1)" "unprognostic (2.22e-2)" "unprognostic (1.45e-1)" "unprognostic (5.38e-2)" "unprognostic (2.12e-1)" "unprognostic (5.27e-3)" "unprognostic (1.57e-3)" "unprognostic (4.90e-2)" "unprognostic (1.17e-1)" "unprognostic (6.49e-2)" "unprognostic (1.59e-1)" "unprognostic (1.68e-2)" "unprognostic (3.03e-2)" "unprognostic (1.67e-1)" "unprognostic (1.52e-1)" "unprognostic (7.57e-3)" "unprognostic (8.33e-2)" "unprognostic (4.26e-3)" "unprognostic (3.08e-1)" "unprognostic (3.29e-2)" "unprognostic (8.42e-2)" "unprognostic (7.30e-3)" "unprognostic (1.18e-1)" "unprognostic (2.63e-2)" "unprognostic (6.58e-3)" "unprognostic (3.02e-1)" TYMS "HsT422, TMS, TS, Tsase" ENSG00000176890 "Thymidylate synthetase" P04818 18 657653-673578 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Nucleotide biosynthesis" "Methyltransferase, Transferase" "Cancer-related genes, Disease variant, Dyskeratosis congenita, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 83.5;lymphoid tissue: 105.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 116.8;Enteric transient amplifying cells: 123.0;Erythrocyte progenitors: 327.1;Esophageal basal cells: 111.6;Extravillous trophoblasts: 122.0;Hofbauer cells: 115.2;Late primary spermatocytes: 286.5;Megakaryocyte progenitors: 335.1;Megakaryocytes: 117.5;Migrating cytotrophoblasts: 143.6;Monocyte progenitors: 198.2" "Cell type enhanced" "Detected in many" "oligodendrocyte: 28.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 14.1" "Group enriched" "Detected in many" 6 "NK-cells: 6.8;T-cells: 14.1" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB002784, HPA074922" Enhanced NA Yes "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 11: White matter - Signal transduction" "Cluster 13: Non-specific - Mixed function" "Cluster 27: Non-specific - Cell proliferation" 2 "CAB002784: , HPA074922: " "unprognostic (1.25e-1)" "unprognostic (1.22e-1)" "unprognostic (4.75e-2)" "unprognostic (2.51e-3)" "unprognostic (1.46e-1)" "unprognostic (1.65e-1)" "unprognostic (1.54e-1)" "unprognostic (3.29e-1)" "unprognostic (2.47e-2)" "unprognostic (4.16e-3)" "potential prognostic favorable (8.73e-6)" "unprognostic (1.24e-2)" "unprognostic (1.49e-2)" "validated prognostic unfavorable (8.34e-5)" "validated prognostic unfavorable (9.99e-7)" "potential prognostic unfavorable (1.45e-6)" "unprognostic (5.67e-3)" "unprognostic (1.17e-1)" "unprognostic (7.07e-2)" "unprognostic (2.91e-1)" "unprognostic (1.29e-3)" "validated prognostic unfavorable (1.81e-6)" "validated prognostic unfavorable (9.64e-4)" "unprognostic (9.74e-3)" "unprognostic (1.03e-1)" "unprognostic (2.85e-1)" "unprognostic (4.60e-2)" "unprognostic (7.34e-2)" "unprognostic (3.62e-1)" "unprognostic (3.53e-2)" "unprognostic (9.65e-2)" TYR "OCA1, OCA1A, OCAIA" ENSG00000077498 Tyrosinase P14679 11 89177875-89295759 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Melanin biosynthesis" "Monooxygenase, Oxidoreductase, Tumor antigen" "Albinism, Deafness, Disease variant, FDA approved drug targets, Waardenburg syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 37 "skin 1: 29.8" "Cell type enriched" "Detected in some" 53 "Melanocytes: 1259.5" "Cell type enhanced" "Detected in some" "hippocampal CA1-3: 5.1;oligodendrocyte: 4.9" "Cancer enriched" "Detected in single" 1325 "Skin Cutaneous Melanoma (TCGA): 765.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 145 "skin cancer: 268.0" "Skin - Melanocytes" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000079, HPA043241, HPA050889, HPA064583" Enhanced Enhanced Vesicles NA NA "Cluster 37: Skin - Keratinization" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 61: Schwann cells & Melanocytes - Mixed function" 1 Vesicles "CAB000079: , HPA043241: , HPA050889: , HPA064583: " "unprognostic (2.19e-1)" TYRO3 "Brt, Dtk, Etk-2, Rek, RSE, Sky, Tif" ENSG00000092445 "TYRO3 protein tyrosine kinase" Q06418 15 41557675-41583589 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 37.9;ovary: 44.4" "Cell type enriched" "Detected in many" 4 "Podocytes: 442.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Enteric glia cells, Kidney - Podocytes, Liver - Vascular endothelial cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071245 Approved NA NA 770000 "Cluster 65: Brain - Transcription" "Cluster 53: Neurons - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 57: Podocytes - Glomerular filtration" 24 "HPA071245: " "unprognostic (1.46e-1)" "unprognostic (6.48e-2)" "unprognostic (2.79e-1)" "unprognostic (1.73e-1)" "unprognostic (1.97e-1)" "unprognostic (1.66e-1)" "unprognostic (2.78e-1)" "unprognostic (1.01e-1)" "unprognostic (3.68e-2)" "unprognostic (5.00e-2)" "unprognostic (2.84e-1)" "unprognostic (3.71e-2)" "potential prognostic unfavorable (1.93e-7)" "potential prognostic unfavorable (2.98e-4)" "unprognostic (2.72e-3)" "unprognostic (1.07e-2)" "unprognostic (2.87e-2)" "unprognostic (1.24e-1)" "unprognostic (7.92e-2)" "unprognostic (7.94e-2)" "unprognostic (3.53e-1)" "unprognostic (3.09e-2)" "unprognostic (5.75e-3)" "unprognostic (2.44e-1)" "unprognostic (2.85e-1)" "unprognostic (1.34e-1)" "unprognostic (2.61e-1)" "unprognostic (2.88e-1)" "unprognostic (2.80e-1)" "unprognostic (1.43e-3)" "unprognostic (9.69e-2)" TYROBP "DAP12, KARAP, PLO-SL, PLOSL" ENSG00000011600 "Transmembrane immune signaling adaptor TYROBP" O43914 19 35904401-35908295 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Immunity "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 562.9;lymphoid tissue: 411.3" "Cell type enhanced" "Detected in many" "cDC: 1347.0;Hofbauer cells: 3768.1;Kupffer cells: 3579.0;Macrophages: 1616.8;Mast cells: 614.0;monocytes: 2170.7;Neutrophils: 2394.5;NK-cells: 645.5;pDCs: 661.7" "Group enriched" "Detected in some" 41 "central nervous system macrophage: 253.3;leukocyte: 106.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 6461.2" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in some" 26 "Leukemia: 111.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Spleen - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009493, HPA041899" Enhanced Supported "Plasma membrane" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 7 "Plasma membrane" "CAB009493: , HPA041899: " "unprognostic (8.04e-2)" "unprognostic (3.48e-2)" "unprognostic (2.39e-1)" "unprognostic (5.28e-2)" "unprognostic (3.68e-2)" "unprognostic (2.76e-1)" "unprognostic (7.87e-2)" "unprognostic (1.18e-1)" "unprognostic (2.56e-1)" "unprognostic (1.03e-1)" "unprognostic (3.40e-3)" "unprognostic (3.56e-1)" "unprognostic (7.16e-2)" "unprognostic (6.71e-2)" "unprognostic (2.06e-1)" "unprognostic (6.02e-2)" "unprognostic (4.25e-2)" "unprognostic (5.87e-2)" "unprognostic (3.05e-1)" "unprognostic (3.66e-1)" "unprognostic (2.97e-1)" "unprognostic (1.22e-1)" "unprognostic (4.16e-2)" "unprognostic (4.79e-2)" "unprognostic (3.32e-2)" "unprognostic (8.22e-2)" "potential prognostic favorable (9.23e-5)" "unprognostic (5.80e-2)" "unprognostic (1.11e-3)" "unprognostic (2.55e-2)" "unprognostic (2.21e-1)" TYRP1 "b-PROTEIN, CAS2, CATB, GP75, OCA3, TRP, TYRP" ENSG00000107165 "Tyrosinase related protein 1" P17643 9 12685439-12710285 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Melanin biosynthesis" "Monooxygenase, Oxidoreductase" "Albinism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "choroid plexus: 67.5;heart muscle: 56.0;skin 1: 137.2" "Group enriched" "Detected in some" 65 "Melanocytes: 4717.1;Retinal pigment epithelial cells: 2285.0" "Cell type enriched" "Detected in some" 17 "choroid plexus epithelial cell: 38.6" "Cancer enriched" "Detected in many" 224 "Skin Cutaneous Melanoma (TCGA): 672.2" "Region enriched" "Detected in many" 16 "choroid plexus: 104.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "skin cancer: 576.9" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Skin - Melanocytes" "Group enriched" "Detected in some" 5 "olfactory bulb: 4.6;thalamus: 1.8" "Low region specificity" "Detected in all" "HPA000937, CAB002520" Enhanced Approved Vesicles NA NA 50000 "Cluster 58: Skin - Keratinization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 61: Schwann cells & Melanocytes - Mixed function" 4 Vesicles "CAB002520: , HPA000937: " "unprognostic (3.27e-2)" "unprognostic (3.13e-2)" "unprognostic (8.99e-2)" "unprognostic (7.18e-3)" "unprognostic (1.37e-1)" "unprognostic (2.74e-1)" "unprognostic (1.04e-1)" "unprognostic (7.52e-2)" "unprognostic (1.87e-2)" "unprognostic (1.62e-1)" "unprognostic (1.84e-2)" "unprognostic (3.95e-1)" "unprognostic (6.66e-2)" TYSND1 "MGC34695, NET41" ENSG00000156521 "Trypsin like peroxisomal matrix peptidase 1" Q2T9J0 10 70137981-70146700 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Early spermatids: 101.1;Late primary spermatocytes: 325.2;Late spermatids: 304.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Spleen - B-cells (Spleen), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030304 Approved Uncertain Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 47: Testis - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 5 "Nucleoplasm, Centrosome" Cytosol "HPA030304: " "unprognostic (3.39e-1)" "unprognostic (3.49e-1)" "unprognostic (8.42e-2)" "unprognostic (1.15e-1)" "unprognostic (2.21e-2)" "unprognostic (1.95e-1)" "unprognostic (1.08e-1)" "potential prognostic favorable (1.73e-6)" "unprognostic (3.26e-1)" "unprognostic (1.50e-1)" "potential prognostic favorable (4.41e-4)" "unprognostic (1.42e-1)" "unprognostic (1.61e-1)" "unprognostic (4.63e-2)" "unprognostic (2.77e-3)" "unprognostic (1.23e-2)" "unprognostic (1.11e-1)" "unprognostic (1.15e-1)" "unprognostic (3.08e-1)" "unprognostic (2.69e-1)" "unprognostic (6.05e-2)" "unprognostic (3.86e-1)" "unprognostic (9.89e-2)" "unprognostic (4.56e-2)" "unprognostic (4.99e-3)" "unprognostic (2.30e-2)" "unprognostic (2.76e-2)" "unprognostic (3.85e-2)" "unprognostic (1.32e-1)" "unprognostic (1.13e-1)" TYW1 "FLJ10900, MGC23001, MGC60291, RSAFD1, TYW1A, YPL207W" ENSG00000198874 "TRNA-yW synthesizing protein 1 homolog" Q9NV66 7 66995173-67239514 "Enzymes, Predicted membrane proteins" "tRNA processing" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 350.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA015535, HPA043136, HPA047029, HPA047052, HPA052097" Approved Approved "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 39: Non-specific - Transcription" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 22 "Nucleoplasm, Nucleoli, Nucleoli rim" "HPA015535: , HPA043136: , HPA047029: , HPA047052: , HPA052097: " "unprognostic (3.19e-1)" "unprognostic (6.33e-2)" "unprognostic (2.22e-1)" "unprognostic (1.16e-1)" "unprognostic (3.51e-1)" "unprognostic (8.18e-2)" "unprognostic (1.82e-1)" "unprognostic (3.21e-2)" "unprognostic (4.10e-1)" "unprognostic (5.08e-2)" "unprognostic (1.96e-3)" "unprognostic (1.34e-1)" "unprognostic (1.53e-1)" "unprognostic (7.00e-3)" "unprognostic (1.36e-2)" "unprognostic (1.45e-2)" "unprognostic (4.26e-2)" "unprognostic (3.70e-2)" "unprognostic (9.06e-3)" "potential prognostic unfavorable (1.84e-4)" "unprognostic (1.22e-1)" "unprognostic (4.34e-1)" "unprognostic (3.34e-3)" "unprognostic (5.02e-1)" "unprognostic (2.91e-1)" "unprognostic (4.64e-3)" "unprognostic (1.24e-1)" "unprognostic (1.80e-1)" "unprognostic (1.16e-1)" "unprognostic (3.77e-3)" "unprognostic (1.28e-1)" TYW1B "LINC00069, MGC87315, NCRNA00069, RSAFD2" ENSG00000277149 "TRNA-yW synthesizing protein 1 homolog B" Q6NUM6 7 72558744-72828200 "Enzymes, Predicted membrane proteins" "tRNA processing" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 12.3" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 271.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "HPA013568, HPA014118, HPA043136, HPA047029, HPA047052, HPA052097" Enhanced Approved "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 2 "Nucleoplasm, Nucleoli, Nucleoli rim" "HPA013568: , HPA014118: , HPA043136: , HPA047029: , HPA047052: , HPA052097: " "unprognostic (1.79e-1)" "unprognostic (3.81e-1)" "unprognostic (1.87e-1)" "unprognostic (3.11e-1)" "unprognostic (7.52e-2)" "unprognostic (3.58e-1)" "unprognostic (1.30e-1)" "unprognostic (8.99e-3)" "unprognostic (5.27e-2)" "unprognostic (1.75e-1)" "unprognostic (3.88e-2)" "unprognostic (9.89e-2)" "unprognostic (8.06e-2)" "unprognostic (1.12e-1)" "unprognostic (3.19e-1)" "unprognostic (4.70e-3)" "unprognostic (1.88e-2)" "unprognostic (3.09e-1)" "unprognostic (1.85e-2)" "unprognostic (1.74e-1)" "unprognostic (3.82e-1)" "potential prognostic favorable (6.67e-4)" "unprognostic (8.10e-2)" "unprognostic (1.36e-1)" "unprognostic (7.70e-2)" "unprognostic (2.96e-1)" "unprognostic (1.89e-1)" "unprognostic (7.13e-3)" TYW3 "C1orf171, FLJ40918" ENSG00000162623 "TRNA-yW synthesizing protein 3 homolog" Q6IPR3 1 74733152-74766678 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029641 Approved Approved "Plasma membrane,Cytosol" No No "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 14 Cytosol "Plasma membrane" "HPA029641: " "unprognostic (6.27e-2)" "unprognostic (6.71e-2)" "unprognostic (1.23e-1)" "unprognostic (1.30e-1)" "unprognostic (8.02e-2)" "unprognostic (8.30e-2)" "unprognostic (1.08e-1)" "unprognostic (1.21e-2)" "unprognostic (1.86e-2)" "unprognostic (1.71e-2)" "potential prognostic favorable (3.65e-7)" "unprognostic (1.90e-3)" "potential prognostic unfavorable (4.34e-4)" "validated prognostic unfavorable (3.24e-9)" "validated prognostic unfavorable (7.25e-4)" "unprognostic (1.85e-2)" "unprognostic (1.94e-1)" "unprognostic (1.08e-1)" "unprognostic (1.20e-2)" "unprognostic (2.83e-1)" "unprognostic (1.18e-2)" "unprognostic (3.18e-2)" "unprognostic (1.04e-1)" "unprognostic (1.94e-1)" "unprognostic (3.24e-2)" "unprognostic (1.93e-2)" "unprognostic (1.98e-1)" "unprognostic (1.80e-1)" "unprognostic (1.64e-1)" "unprognostic (4.54e-2)" "unprognostic (2.67e-1)" TYW5 "C2orf60, FLJ37953" ENSG00000162971 "TRNA-yW synthesizing protein 5" A2RUC4 2 199928913-199955736 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA045803 Uncertain Approved Mitochondria NA NA "Cluster 64: Non-specific - Transcription" "Cluster 9: Non-specific - Receptor signaling" "Cluster 56: Non-specific - Sensory perception" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 1 Mitochondria "HPA045803: " "unprognostic (1.28e-2)" "unprognostic (2.05e-2)" "unprognostic (9.12e-3)" "unprognostic (6.54e-3)" "unprognostic (1.06e-1)" "unprognostic (5.83e-2)" "unprognostic (2.53e-3)" "unprognostic (3.24e-2)" "unprognostic (3.60e-3)" "unprognostic (1.46e-3)" "unprognostic (1.83e-1)" "unprognostic (2.16e-1)" "potential prognostic unfavorable (9.15e-4)" "unprognostic (1.93e-1)" "unprognostic (1.73e-1)" "unprognostic (2.91e-1)" "unprognostic (1.95e-1)" "unprognostic (4.53e-2)" "unprognostic (8.49e-2)" "unprognostic (4.92e-1)" "unprognostic (1.41e-1)" "unprognostic (1.15e-3)" "unprognostic (1.72e-2)" "unprognostic (2.05e-1)" "unprognostic (2.15e-1)" "unprognostic (1.09e-3)" "unprognostic (1.91e-1)" "unprognostic (1.42e-1)" "unprognostic (1.78e-1)" "unprognostic (1.18e-1)" U2AF1 "RN, RNU2AF1, U2AF35, U2AFBP" ENSG00000160201 "U2 small nuclear RNA auxiliary factor 1" Q01081 21 43092956-43107570 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 33.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044833, HPA052083" Supported Enhanced Nucleoplasm NA NA 250000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 47: Leukemia - Hemostasis" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 68 Nucleoplasm "HPA044833: , HPA052083: " "unprognostic (2.67e-2)" "unprognostic (1.44e-1)" "unprognostic (2.72e-1)" "unprognostic (1.13e-3)" "unprognostic (1.91e-1)" "unprognostic (2.17e-1)" "unprognostic (7.46e-2)" "unprognostic (1.22e-2)" "unprognostic (2.24e-1)" "unprognostic (2.74e-1)" "unprognostic (3.10e-2)" "unprognostic (5.83e-2)" "unprognostic (1.61e-1)" "unprognostic (7.15e-2)" "potential prognostic unfavorable (3.83e-5)" "unprognostic (2.08e-2)" "unprognostic (7.85e-3)" "unprognostic (3.30e-2)" "unprognostic (1.93e-1)" "unprognostic (4.84e-2)" "unprognostic (2.58e-1)" "unprognostic (1.13e-1)" "unprognostic (6.76e-2)" "unprognostic (1.75e-2)" "unprognostic (7.73e-3)" "unprognostic (4.63e-1)" "unprognostic (1.62e-2)" "unprognostic (1.11e-1)" "unprognostic (3.92e-2)" "unprognostic (5.17e-3)" "unprognostic (7.29e-2)" U2AF1L4 "MGC33901, U2AF1L3, U2af26" ENSG00000161265 "U2 small nuclear RNA auxiliary factor 1 like 4" Q8WU68 19 35742464-35745445 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 32.0;Tuft cells: 23.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052083, HPA061644" Supported Approved Nucleoplasm NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 14: Neurons - Synaptic function" "Cluster 4: Non-specific - Transcription" "Cluster 67: Plasma cells - Plasma cell differentiation" Nucleoplasm "HPA052083: , HPA061644: " "unprognostic (4.98e-2)" "unprognostic (6.83e-2)" "unprognostic (3.36e-2)" "unprognostic (1.04e-1)" "unprognostic (2.30e-1)" "unprognostic (1.01e-2)" "unprognostic (7.92e-2)" "unprognostic (1.06e-1)" "unprognostic (2.68e-1)" "unprognostic (4.11e-2)" "unprognostic (1.45e-1)" "unprognostic (1.68e-1)" "unprognostic (2.32e-1)" "unprognostic (1.65e-2)" "unprognostic (7.19e-2)" "potential prognostic unfavorable (9.99e-5)" "unprognostic (1.29e-1)" "unprognostic (1.18e-1)" "unprognostic (2.65e-1)" "unprognostic (8.23e-2)" "unprognostic (3.59e-1)" "unprognostic (1.36e-2)" "unprognostic (2.67e-1)" "unprognostic (3.51e-1)" "unprognostic (1.57e-1)" "unprognostic (4.04e-1)" "unprognostic (2.77e-1)" "unprognostic (7.71e-2)" "unprognostic (9.23e-2)" "unprognostic (1.53e-1)" "unprognostic (1.56e-1)" U2AF2 U2AF65 ENSG00000063244 "U2 small nuclear RNA auxiliary factor 2" P26368 19 55654146-55674716 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Repressor, RNA-binding" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010910, HPA041943, HPA043562" Supported Supported Supported "Nucleoplasm,Nuclear speckles" NA NA 100000 "Cluster 7: Non-specific - Innate immune response" "Cluster 49: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 18: Adrenal cortex cells - Steroidogensis" 211 "Nucleoplasm, Nuclear speckles" "CAB010910: , HPA041943: , HPA043562: " "unprognostic (1.78e-1)" "unprognostic (2.56e-1)" "unprognostic (2.90e-1)" "unprognostic (1.95e-2)" "unprognostic (1.04e-1)" "unprognostic (1.24e-1)" "unprognostic (9.55e-2)" "unprognostic (8.29e-2)" "unprognostic (8.94e-2)" "unprognostic (8.85e-3)" "unprognostic (9.24e-2)" "unprognostic (2.72e-2)" "unprognostic (3.65e-1)" "potential prognostic unfavorable (2.69e-8)" "unprognostic (2.74e-3)" "unprognostic (5.29e-3)" "unprognostic (2.19e-3)" "unprognostic (2.86e-2)" "unprognostic (9.33e-2)" "unprognostic (3.38e-1)" "unprognostic (5.13e-2)" "unprognostic (2.64e-1)" "unprognostic (3.00e-2)" "potential prognostic unfavorable (5.56e-4)" "unprognostic (1.20e-1)" "unprognostic (8.74e-3)" "unprognostic (2.22e-2)" "unprognostic (1.58e-1)" "unprognostic (2.70e-1)" "unprognostic (1.76e-1)" "unprognostic (1.16e-2)" U2SURP "fSAPa, SR140" ENSG00000163714 "U2 snRNP associated SURP domain containing" O15042 3 142964497-143060725 "Essential proteins, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037545, HPA037546, HPA061407" Enhanced Supported Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 40: Non-specific - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 17: Non-specific - RNA processing" 77 Nucleoplasm "HPA037545: , HPA037546: , HPA061407: " "unprognostic (8.74e-2)" "unprognostic (5.62e-2)" "unprognostic (6.11e-2)" "unprognostic (1.30e-1)" "unprognostic (5.54e-2)" "unprognostic (2.36e-1)" "unprognostic (5.66e-2)" "unprognostic (5.54e-2)" "unprognostic (1.32e-2)" "unprognostic (1.37e-2)" "unprognostic (2.68e-1)" "unprognostic (4.62e-2)" "potential prognostic unfavorable (8.51e-5)" "unprognostic (1.73e-1)" "potential prognostic unfavorable (4.28e-4)" "unprognostic (4.78e-3)" "unprognostic (1.30e-1)" "unprognostic (1.20e-1)" "unprognostic (3.41e-1)" "unprognostic (1.98e-1)" "potential prognostic unfavorable (7.13e-4)" "unprognostic (1.86e-3)" "unprognostic (2.88e-3)" "unprognostic (1.27e-1)" "unprognostic (2.58e-2)" "unprognostic (1.73e-2)" "unprognostic (1.01e-1)" "unprognostic (2.15e-1)" "unprognostic (1.64e-1)" "unprognostic (2.63e-2)" UACA "FLJ10128, KIAA1561" ENSG00000137831 "Uveal autoantigen with coiled-coil domains and ankyrin repeats" Q9BZF9 15 70654554-70763558 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 133.9" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 457.4;Myonuclei: 796.3;Podocytes: 994.7;Retinal pigment epithelial cells: 417.8" "Cell type enhanced" "Detected in many" "endothelial cell: 498.0;fibroblast: 1031.7;pericyte: 506.0;vascular associated smooth muscle cell: 364.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Minor Salivary Gland - Endothelial cells, Pituitary gland - Fibroblasts, Spleen - Endothelial cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041412, HPA043503, HPA056006" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 19 Nucleoplasm Cytosol "HPA041412: , HPA043503: , HPA056006: " "unprognostic (1.26e-1)" "unprognostic (2.97e-1)" "unprognostic (2.72e-1)" "unprognostic (2.16e-1)" "unprognostic (5.03e-2)" "unprognostic (1.04e-1)" "unprognostic (2.76e-1)" "unprognostic (1.53e-1)" "unprognostic (8.63e-2)" "unprognostic (4.98e-3)" "unprognostic (1.25e-3)" "potential prognostic favorable (1.07e-4)" "unprognostic (5.29e-2)" "unprognostic (7.97e-2)" "unprognostic (7.09e-2)" "unprognostic (3.57e-2)" "unprognostic (6.97e-2)" "unprognostic (2.67e-1)" "unprognostic (3.00e-2)" "unprognostic (1.34e-1)" "unprognostic (2.74e-2)" "potential prognostic unfavorable (2.13e-5)" "unprognostic (5.56e-3)" "unprognostic (6.22e-2)" "unprognostic (2.34e-2)" "unprognostic (1.68e-1)" "unprognostic (1.30e-1)" "unprognostic (5.32e-2)" "unprognostic (2.56e-1)" "unprognostic (4.01e-2)" "unprognostic (7.20e-2)" UAP1 "AgX, AGX1, SPAG2" ENSG00000117143 "UDP-N-acetylglucosamine pyrophosphorylase 1" Q16222 1 162561722-162601240 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 93.9" "Cell type enhanced" "Detected in many" "Epicardial cells: 307.0;Fibroblasts: 395.8;Late primary spermatocytes: 314.1;Pancreatic acinar cells: 301.9;Salivary acinar cells: 302.9" "Group enriched" "Detected in all" 4 "fibroblast: 81.3;vascular associated smooth muscle cell: 178.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014659 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" No Yes 34000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 57: Testis - Spermatogenesis" "Cluster 1: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 103: Non-specific - Basic cellular processes" 1 "Nucleoplasm, Plasma membrane, Cytosol" "HPA014659: " "unprognostic (2.14e-1)" "unprognostic (9.26e-2)" "unprognostic (9.61e-2)" "unprognostic (4.05e-2)" "unprognostic (3.30e-2)" "unprognostic (1.18e-1)" "unprognostic (1.11e-2)" "unprognostic (1.01e-1)" "unprognostic (1.23e-2)" "unprognostic (6.75e-2)" "unprognostic (8.74e-3)" "unprognostic (1.11e-1)" "potential prognostic unfavorable (2.33e-4)" "unprognostic (1.90e-2)" "unprognostic (2.86e-2)" "potential prognostic unfavorable (9.39e-4)" "unprognostic (1.09e-3)" "unprognostic (7.11e-2)" "unprognostic (1.58e-1)" "unprognostic (6.79e-2)" "unprognostic (3.63e-2)" "unprognostic (1.75e-2)" "unprognostic (3.96e-2)" "unprognostic (1.81e-1)" "unprognostic (2.11e-1)" "potential prognostic unfavorable (1.78e-4)" "unprognostic (1.20e-1)" "unprognostic (1.78e-1)" "unprognostic (4.32e-2)" "unprognostic (2.93e-1)" "unprognostic (9.42e-2)" UAP1L1 ENSG00000197355 "UDP-N-acetylglucosamine pyrophosphorylase 1 like 1" Q3KQV9 9 137077517-137084539 "Metabolic proteins, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 25.0;Choroid plexus epithelial cells: 19.4;Hofbauer cells: 31.8;Oligodendrocytes: 23.2;Retinal ganglion cells: 19.3;Retinal pigment epithelial cells: 21.3" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 33.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044356 Approved Approved "Intermediate filaments,Cytosol" No No "Cluster 13: Non-specific - Mitochondria" "Cluster 5: Spleen - Immune response" "Cluster 11: White matter - Signal transduction" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 1 "Intermediate filaments" Cytosol "HPA044356: " "unprognostic (1.40e-1)" "unprognostic (6.94e-3)" "unprognostic (1.41e-1)" "unprognostic (1.33e-1)" "unprognostic (1.92e-2)" "unprognostic (2.42e-1)" "unprognostic (1.15e-2)" "unprognostic (9.87e-2)" "unprognostic (1.74e-1)" "unprognostic (7.89e-2)" "unprognostic (5.51e-2)" "unprognostic (2.15e-1)" "unprognostic (2.45e-1)" "potential prognostic unfavorable (4.59e-6)" "unprognostic (3.10e-1)" "unprognostic (5.52e-2)" "unprognostic (5.62e-2)" "unprognostic (2.37e-1)" "unprognostic (1.89e-2)" "unprognostic (9.84e-2)" "unprognostic (3.42e-1)" "unprognostic (1.35e-3)" "unprognostic (6.57e-3)" "unprognostic (2.07e-1)" "unprognostic (1.58e-1)" "unprognostic (9.32e-2)" "unprognostic (8.01e-2)" "unprognostic (5.50e-2)" "unprognostic (8.03e-2)" "unprognostic (3.47e-2)" "unprognostic (1.62e-2)" UBA1 "A1S9T, CFAP124, GXP1, POC20, UBE1, UBE1X" ENSG00000130985 "Ubiquitin like modifier activating enzyme 1" P22314 X 47190861-47215128 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Ligase "Cancer-related genes, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 225.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000289, HPA001506, CAB019435, CAB073410" Approved Supported Nucleoplasm,Cytosol NA NA 16000000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 36: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 95 Nucleoplasm Cytosol "CAB019435: , CAB073410: , HPA000289: , HPA001506: " "unprognostic (1.40e-1)" "unprognostic (4.36e-3)" "unprognostic (3.50e-1)" "unprognostic (1.37e-2)" "unprognostic (1.56e-1)" "unprognostic (2.20e-2)" "unprognostic (1.39e-1)" "unprognostic (1.51e-1)" "unprognostic (1.01e-2)" "unprognostic (1.03e-2)" "unprognostic (1.12e-3)" "unprognostic (1.11e-1)" "unprognostic (1.13e-1)" "potential prognostic unfavorable (6.78e-4)" "unprognostic (1.05e-2)" "unprognostic (2.48e-3)" "unprognostic (3.00e-3)" "unprognostic (2.18e-1)" "unprognostic (5.43e-2)" "unprognostic (1.99e-1)" "unprognostic (3.32e-1)" "potential prognostic unfavorable (6.10e-4)" "unprognostic (3.88e-1)" "unprognostic (4.68e-2)" "unprognostic (4.49e-1)" "unprognostic (9.25e-2)" "unprognostic (2.65e-1)" "unprognostic (2.00e-2)" "unprognostic (1.30e-1)" "unprognostic (1.24e-2)" "unprognostic (2.54e-1)" UBA2 "FLJ13058, HRIHFB2115, SAE2" ENSG00000126261 "Ubiquitin like modifier activating enzyme 2" Q9UBT2 19 34428352-34471251 "Disease related genes, Essential proteins, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Vascular smooth muscle cells: 387.7" "Cell type enhanced" "Detected in all" "vascular associated smooth muscle cell: 400.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" HPA041436 Supported Supported Nucleoplasm NA NA 85000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 39: Testis - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 110: Mural cells - ECM organization" 23 Nucleoplasm "HPA041436: " "unprognostic (3.35e-2)" "unprognostic (3.39e-1)" "unprognostic (7.17e-3)" "unprognostic (2.19e-2)" "unprognostic (3.11e-1)" "unprognostic (4.21e-1)" "unprognostic (2.38e-2)" "unprognostic (1.53e-1)" "unprognostic (1.15e-2)" "unprognostic (4.76e-2)" "potential prognostic favorable (1.83e-4)" "unprognostic (8.57e-3)" "unprognostic (1.15e-1)" "validated prognostic unfavorable (1.68e-4)" "validated prognostic unfavorable (7.80e-4)" "unprognostic (2.37e-3)" "unprognostic (1.98e-2)" "unprognostic (7.58e-3)" "unprognostic (1.24e-1)" "unprognostic (1.26e-1)" "unprognostic (9.91e-2)" "unprognostic (8.87e-2)" "unprognostic (1.70e-2)" "unprognostic (5.15e-2)" "unprognostic (8.17e-3)" "unprognostic (1.18e-1)" "unprognostic (3.56e-3)" "unprognostic (3.81e-2)" "unprognostic (2.84e-1)" "unprognostic (1.38e-1)" "unprognostic (1.58e-1)" UBA3 "hUba3, NAE2, UBE1C" ENSG00000144744 "Ubiquitin like modifier activating enzyme 3" Q8TBC4 3 69054730-69080408 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Ubl conjugation pathway" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034873, HPA034874, HPA065335" Supported Approved "Nucleoplasm,Plasma membrane,Centrosome,Cytosol" NA NA 21000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 61: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 24: Neutrophils - Innate immunity signal integration" 18 "Plasma membrane, Cytosol" "Nucleoplasm, Centrosome" "HPA034873: , HPA034874: , HPA065335: " "unprognostic (2.44e-3)" "unprognostic (2.00e-1)" "unprognostic (1.98e-1)" "unprognostic (2.63e-1)" "unprognostic (1.25e-1)" "unprognostic (1.74e-2)" "unprognostic (9.08e-2)" "unprognostic (1.52e-1)" "unprognostic (1.46e-1)" "unprognostic (1.93e-2)" "unprognostic (1.49e-1)" "unprognostic (1.29e-1)" "unprognostic (4.44e-3)" "unprognostic (9.73e-3)" "unprognostic (4.37e-2)" "unprognostic (1.20e-1)" "unprognostic (1.47e-2)" "unprognostic (1.96e-2)" "unprognostic (1.11e-1)" "unprognostic (4.13e-3)" "unprognostic (3.21e-2)" "unprognostic (2.60e-2)" "unprognostic (2.91e-2)" "unprognostic (3.45e-2)" "potential prognostic favorable (8.30e-4)" "unprognostic (7.53e-2)" "unprognostic (1.14e-1)" "unprognostic (3.60e-3)" "unprognostic (3.60e-2)" "unprognostic (2.87e-1)" "unprognostic (1.03e-1)" UBA5 "FLJ23251, UBE1DC1" ENSG00000081307 "Ubiquitin like modifier activating enzyme 5" Q9GZZ9 3 132654446-132679794 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Disease variant, Epilepsy, Intellectual disability, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 259.7;Late spermatids: 735.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017235, HPA076042" Supported Enhanced Vesicles,Cytosol NA NA 26000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 29 "Vesicles, Cytosol" "HPA017235: , HPA076042: " "unprognostic (2.08e-1)" "potential prognostic unfavorable (1.41e-4)" "unprognostic (7.70e-2)" "unprognostic (1.20e-1)" "unprognostic (1.06e-1)" "unprognostic (2.31e-2)" "unprognostic (4.40e-2)" "unprognostic (1.56e-1)" "unprognostic (6.71e-2)" "unprognostic (4.23e-2)" "potential prognostic favorable (3.05e-6)" "unprognostic (9.07e-3)" "unprognostic (3.44e-3)" "unprognostic (7.08e-3)" "unprognostic (1.44e-1)" "unprognostic (9.61e-3)" "unprognostic (1.97e-1)" "unprognostic (3.90e-1)" "unprognostic (4.10e-3)" "unprognostic (1.61e-1)" "unprognostic (3.14e-2)" "unprognostic (1.51e-2)" "unprognostic (2.70e-3)" "unprognostic (4.10e-2)" "unprognostic (7.06e-3)" "unprognostic (2.21e-1)" "unprognostic (1.96e-1)" "unprognostic (1.82e-1)" "unprognostic (1.69e-1)" "unprognostic (2.52e-2)" "unprognostic (2.58e-1)" UBA52 "CEP52, HUBCEP52, L40, MGC126879, MGC126881, MGC57125, RPL40" ENSG00000221983 "Ubiquitin A-52 residue ribosomal protein fusion product 1" P62987 19 18571730-18577550 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 5661.2;Esophageal suprabasal cells: 4722.0;Late spermatids: 20333.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041344, HPA049132, HPA056624" Supported Approved "Nucleoplasm,Endoplasmic reticulum,Plasma membrane,Cytosol,Acrosome,Equatorial segment" NA NA "Cluster 18: Non-specific - Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 84 Cytosol "Nucleoplasm, Endoplasmic reticulum, Plasma membrane, Acrosome, Equatorial segment" "HPA041344: , HPA049132: , HPA056624: " "unprognostic (1.67e-1)" "unprognostic (7.74e-2)" "unprognostic (1.80e-2)" "unprognostic (1.23e-1)" "unprognostic (2.36e-1)" "unprognostic (2.44e-1)" "unprognostic (1.18e-2)" "unprognostic (2.80e-1)" "unprognostic (1.61e-1)" "unprognostic (3.74e-2)" "unprognostic (5.80e-3)" "unprognostic (6.15e-2)" "unprognostic (6.40e-3)" "validated prognostic unfavorable (2.21e-4)" "validated prognostic unfavorable (6.10e-5)" "unprognostic (2.54e-1)" "unprognostic (3.49e-2)" "unprognostic (6.14e-2)" "unprognostic (2.23e-1)" "unprognostic (2.62e-1)" "unprognostic (5.14e-2)" "unprognostic (1.60e-1)" "unprognostic (1.96e-1)" "unprognostic (6.83e-2)" "unprognostic (1.40e-2)" "unprognostic (5.87e-2)" "unprognostic (2.74e-2)" "unprognostic (3.63e-2)" "unprognostic (3.31e-2)" "unprognostic (9.15e-2)" "unprognostic (4.16e-2)" UBA6 "FLJ10808, UBE1L2" ENSG00000033178 "Ubiquitin like modifier activating enzyme 6" A0AVT1 4 67612652-67701155 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037001 Approved Enhanced Nucleoplasm,Cytosol NA NA 7800 "Cluster 32: Basophils - Transcription" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 30: White matter - Myelination" "Cluster 15: Kidney cancer - Membrane components" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 30 "Nucleoplasm, Cytosol" "HPA037001: " "unprognostic (3.02e-1)" "unprognostic (1.01e-1)" "unprognostic (1.36e-1)" "unprognostic (7.00e-3)" "unprognostic (6.31e-2)" "unprognostic (2.26e-1)" "unprognostic (1.79e-1)" "unprognostic (3.65e-2)" "unprognostic (2.17e-1)" "unprognostic (6.62e-3)" "unprognostic (8.38e-2)" "unprognostic (5.01e-1)" "unprognostic (1.78e-1)" "unprognostic (4.72e-3)" "unprognostic (1.91e-1)" "unprognostic (2.34e-3)" "unprognostic (7.81e-3)" "unprognostic (1.37e-1)" "unprognostic (2.97e-1)" "unprognostic (1.37e-1)" "unprognostic (1.85e-1)" "unprognostic (4.38e-3)" "potential prognostic unfavorable (4.81e-5)" "unprognostic (3.15e-1)" "unprognostic (9.50e-3)" "unprognostic (2.84e-1)" "unprognostic (7.24e-2)" "unprognostic (4.46e-1)" "unprognostic (2.53e-1)" "unprognostic (1.70e-2)" "unprognostic (4.20e-2)" UBA7 "D8, UBA1B, UBE1L, UBE2" ENSG00000182179 "Ubiquitin like modifier activating enzyme 7" P41226 3 49805209-49813953 "Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Host-virus interaction, Ubl conjugation pathway" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Megakaryocytes: 105.1;Platelets: 338.3" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 45.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 30.9" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "CAB015444, HPA058182" Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA 1000000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 47: Platelets - Hemostasis" 7 "Nucleoplasm, Vesicles" Cytosol "CAB015444: , HPA058182: " "unprognostic (8.74e-2)" "potential prognostic favorable (1.42e-4)" "unprognostic (1.10e-2)" "unprognostic (4.42e-2)" "unprognostic (1.96e-1)" "unprognostic (9.08e-2)" "unprognostic (1.68e-1)" "unprognostic (2.13e-2)" "unprognostic (4.68e-2)" "unprognostic (4.20e-3)" "unprognostic (1.56e-2)" "unprognostic (3.75e-1)" "unprognostic (1.47e-2)" "unprognostic (4.34e-2)" "potential prognostic favorable (5.64e-4)" "unprognostic (1.77e-2)" "unprognostic (5.78e-2)" "unprognostic (1.38e-1)" "unprognostic (7.40e-2)" "unprognostic (1.42e-1)" "unprognostic (9.33e-3)" "unprognostic (1.23e-1)" "unprognostic (1.12e-1)" "unprognostic (2.20e-1)" "unprognostic (7.64e-3)" "unprognostic (1.45e-1)" "unprognostic (1.38e-1)" "unprognostic (2.46e-1)" "unprognostic (1.13e-2)" "unprognostic (2.20e-1)" "unprognostic (2.57e-2)" UBAC1 "GBDR1, KPC2, UBADC1" ENSG00000130560 "UBA domain containing 1" Q9BSL1 9 135932969-135961373 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 290.9;tongue: 159.7" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 373.7;Late spermatids: 340.5;Respiratory ciliated cells: 235.9;Thymic myoid cells: 407.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005651 Approved Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA 70000 "Cluster 25: Non-specific - Unknown function" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 19: Astrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 42 "Plasma membrane, Cytosol" "Golgi apparatus" "HPA005651: " "unprognostic (2.32e-2)" "unprognostic (7.60e-3)" "unprognostic (3.72e-1)" "potential prognostic favorable (9.97e-4)" "unprognostic (1.04e-1)" "unprognostic (1.23e-2)" "unprognostic (1.00e-1)" "unprognostic (1.11e-1)" "unprognostic (3.20e-2)" "unprognostic (1.80e-1)" "potential prognostic favorable (1.06e-5)" "unprognostic (6.49e-3)" "unprognostic (1.86e-2)" "unprognostic (3.20e-3)" "potential prognostic unfavorable (5.08e-4)" "unprognostic (3.40e-1)" "unprognostic (6.31e-2)" "unprognostic (1.40e-1)" "unprognostic (5.60e-2)" "unprognostic (3.73e-2)" "unprognostic (9.04e-2)" "unprognostic (9.30e-2)" "unprognostic (3.52e-2)" "unprognostic (7.03e-2)" "unprognostic (3.56e-1)" "unprognostic (7.10e-3)" "unprognostic (3.19e-1)" "unprognostic (4.05e-3)" "unprognostic (1.76e-1)" "unprognostic (2.32e-2)" "unprognostic (2.57e-1)" UBAC2 "FLJ30548, PHGDHL1, RP11-178C10.1" ENSG00000134882 "UBA domain containing 2" Q8NBM4 13 99200774-99386504 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013448 Approved Approved Cytosol NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 43 Cytosol "HPA013448: " "unprognostic (1.24e-1)" "unprognostic (9.95e-2)" "unprognostic (7.19e-2)" "unprognostic (1.03e-2)" "unprognostic (8.35e-2)" "unprognostic (4.59e-2)" "unprognostic (9.06e-2)" "unprognostic (1.50e-1)" "unprognostic (2.63e-3)" "unprognostic (5.46e-2)" "potential prognostic favorable (5.45e-9)" "unprognostic (2.78e-2)" "unprognostic (1.56e-1)" "unprognostic (3.93e-2)" "potential prognostic unfavorable (7.31e-5)" "potential prognostic unfavorable (2.76e-4)" "unprognostic (9.54e-3)" "potential prognostic unfavorable (8.37e-4)" "unprognostic (4.20e-1)" "unprognostic (1.01e-2)" "unprognostic (2.74e-2)" "unprognostic (1.17e-3)" "unprognostic (9.07e-3)" "unprognostic (5.50e-2)" "unprognostic (8.66e-2)" "unprognostic (4.99e-1)" "unprognostic (2.99e-1)" "unprognostic (2.30e-1)" "unprognostic (3.16e-1)" "unprognostic (7.72e-2)" "unprognostic (2.02e-1)" UBALD1 FAM100A ENSG00000153443 "UBA like domain containing 1" Q8TB05 16 4608883-4615027 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 99.1;Esophageal apical cells: 109.5;Late spermatids: 248.1;Suprabasal keratinocytes: 94.7;Syncytiotrophoblasts: 154.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 8.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066771 Approved Approved "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 26: Keratinocytes - Keratinization" "Nucleoplasm, Cytosol" "Cell Junctions" "HPA066771: " "unprognostic (2.67e-2)" "unprognostic (4.45e-2)" "unprognostic (2.42e-1)" "unprognostic (1.78e-1)" "unprognostic (8.61e-2)" "unprognostic (3.09e-1)" "unprognostic (1.23e-3)" "unprognostic (1.28e-1)" "unprognostic (5.21e-3)" "unprognostic (3.66e-2)" "unprognostic (6.26e-2)" "unprognostic (4.57e-2)" "unprognostic (4.99e-1)" "unprognostic (8.85e-2)" "unprognostic (2.09e-1)" "unprognostic (6.33e-2)" "unprognostic (3.34e-2)" "unprognostic (2.70e-2)" "unprognostic (1.18e-1)" "unprognostic (2.49e-2)" "unprognostic (2.30e-3)" "unprognostic (2.26e-1)" "unprognostic (4.59e-2)" "unprognostic (1.69e-2)" "unprognostic (1.94e-1)" "unprognostic (6.81e-2)" "unprognostic (5.26e-2)" "unprognostic (1.36e-2)" "unprognostic (9.38e-2)" UBALD2 "FAM100B, MGC29814" ENSG00000185262 "UBA like domain containing 2" Q8IYN6 17 76265348-76271298 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 215.4" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 280.5;Neutrophils: 399.2;Platelets: 225.9" "Cell type enhanced" "Detected in all" "leukocyte: 66.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 7.8;neutrophil: 29.3" "Lineage enriched" "Detected in all" 6 "granulocytes: 29.3" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023046 Uncertain NA Yes "Cluster 21: Neutrophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 29: Neutrophils - Innate immune cellular maintenance" "HPA023046: " "unprognostic (1.60e-1)" "unprognostic (2.79e-1)" "unprognostic (2.70e-1)" "unprognostic (1.37e-1)" "unprognostic (1.22e-3)" "unprognostic (4.40e-2)" "unprognostic (1.84e-2)" "unprognostic (3.06e-2)" "unprognostic (1.19e-3)" "unprognostic (2.56e-2)" "unprognostic (2.59e-1)" "unprognostic (1.55e-1)" "potential prognostic unfavorable (3.48e-6)" "unprognostic (3.97e-3)" "unprognostic (1.89e-3)" "unprognostic (2.24e-1)" "unprognostic (2.92e-1)" "unprognostic (1.38e-1)" "unprognostic (1.43e-1)" "unprognostic (4.31e-2)" "unprognostic (8.56e-2)" "unprognostic (1.05e-2)" "unprognostic (6.33e-2)" "unprognostic (1.41e-1)" "unprognostic (5.40e-2)" "unprognostic (5.53e-2)" "unprognostic (1.71e-1)" "unprognostic (8.12e-2)" "unprognostic (5.73e-2)" UBAP1 UBAP ENSG00000165006 "Ubiquitin associated protein 1" Q9NZ09 9 34179005-34252523 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 820.0;Neutrophils: 2090.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019804 Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 11 Cytosol "Vesicles, Plasma membrane" "HPA019804: " "unprognostic (7.34e-2)" "unprognostic (2.73e-1)" "unprognostic (3.22e-3)" "unprognostic (5.41e-3)" "unprognostic (1.35e-1)" "unprognostic (1.14e-3)" "unprognostic (1.95e-1)" "unprognostic (6.13e-3)" "unprognostic (9.34e-2)" "unprognostic (4.08e-2)" "potential prognostic favorable (3.34e-6)" "unprognostic (4.17e-2)" "unprognostic (3.11e-2)" "unprognostic (3.46e-2)" "unprognostic (1.18e-1)" "unprognostic (1.73e-1)" "potential prognostic unfavorable (1.21e-6)" "unprognostic (4.01e-2)" "unprognostic (4.47e-2)" "unprognostic (5.89e-2)" "unprognostic (8.74e-2)" "unprognostic (2.51e-2)" "unprognostic (1.64e-2)" "unprognostic (3.37e-1)" "unprognostic (2.69e-1)" "unprognostic (8.92e-2)" "unprognostic (3.36e-2)" "unprognostic (2.35e-1)" "unprognostic (3.92e-1)" "unprognostic (2.87e-2)" "unprognostic (8.86e-2)" UBAP1L ENSG00000246922 "Ubiquitin associated protein 1 like" F5GYI3 15 65092760-65115200 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 15.5;retina: 24.5" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 66.4;Cone photoreceptor cells: 275.3;Retinal bipolar cells: 69.5;Retinal pigment epithelial cells: 140.7;Rod photoreceptor cells: 292.5" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in single" 5 "Skin Cutaneous Melanoma (TCGA): 4.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 16 "skin cancer: 10.4" "Low region specificity" "Detected in many" "Region enhanced" "Detected in all" "cerebellum: 35.1" HPA065334 Uncertain "Nuclear bodies" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 9: Non-specific - Receptor signaling" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 79: Photoreceptor cells - Phototransduction" "Nuclear bodies" "HPA065334: " "unprognostic (4.26e-2)" "unprognostic (1.61e-3)" "unprognostic (9.01e-3)" "unprognostic (1.25e-2)" "unprognostic (4.69e-3)" "unprognostic (5.13e-2)" "unprognostic (3.25e-2)" UBAP2 "bA176F3.5, FLJ22435, KIAA1491" ENSG00000137073 "Ubiquitin associated protein 2" Q5T6F2 9 33921693-34049388 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 92.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021684 Approved Approved Cytosol NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 16: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 20: Non-specific - Transcription regulation" 33 Cytosol "HPA021684: " "unprognostic (2.40e-1)" "unprognostic (1.84e-1)" "unprognostic (7.11e-2)" "unprognostic (1.17e-1)" "unprognostic (4.21e-2)" "unprognostic (5.19e-2)" "unprognostic (1.72e-1)" "unprognostic (1.37e-2)" "unprognostic (4.83e-3)" "unprognostic (5.78e-3)" "potential prognostic favorable (3.59e-5)" "unprognostic (1.87e-2)" "unprognostic (2.16e-1)" "validated prognostic unfavorable (3.23e-10)" "validated prognostic unfavorable (1.66e-4)" "unprognostic (4.46e-3)" "potential prognostic unfavorable (3.89e-5)" "unprognostic (2.39e-1)" "unprognostic (5.66e-2)" "unprognostic (9.06e-3)" "unprognostic (5.31e-2)" "unprognostic (4.57e-1)" "unprognostic (1.65e-2)" "unprognostic (6.38e-2)" "unprognostic (1.68e-1)" "unprognostic (3.72e-1)" "unprognostic (2.12e-2)" "unprognostic (3.44e-2)" "unprognostic (1.55e-1)" "unprognostic (2.45e-1)" "unprognostic (1.38e-1)" UBAP2L "KIAA0144, NICE-4" ENSG00000143569 "Ubiquitin associated protein 2 like" Q14157 1 154220179-154271510 "Predicted intracellular proteins" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 313.0;Epicardial cells: 247.9;Late spermatids: 226.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035068 Approved Approved "Nuclear speckles,Cytosol" NA NA 19000 "Cluster 7: Non-specific - Innate immune response" "Cluster 61: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 45: Non-specific - Nuclear processes" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 41 "Nuclear speckles, Cytosol" "HPA035068: " "unprognostic (2.28e-1)" "unprognostic (9.59e-2)" "unprognostic (2.65e-1)" "unprognostic (1.00e-1)" "unprognostic (3.96e-1)" "unprognostic (1.23e-2)" "unprognostic (8.33e-2)" "unprognostic (2.86e-2)" "unprognostic (9.21e-2)" "unprognostic (1.49e-3)" "unprognostic (4.00e-3)" "unprognostic (1.08e-1)" "unprognostic (2.98e-3)" "potential prognostic unfavorable (2.08e-5)" "unprognostic (1.07e-1)" "unprognostic (1.53e-1)" "unprognostic (4.50e-3)" "unprognostic (4.80e-2)" "unprognostic (5.14e-2)" "unprognostic (2.58e-1)" "unprognostic (3.72e-1)" "unprognostic (2.54e-2)" "potential prognostic unfavorable (6.95e-4)" "unprognostic (1.28e-1)" "unprognostic (1.69e-1)" "unprognostic (2.79e-1)" "unprognostic (5.25e-2)" "unprognostic (9.87e-3)" "unprognostic (1.30e-1)" "unprognostic (3.89e-2)" "unprognostic (7.99e-3)" UBASH3A "CLIP4, STS-2, TULA" ENSG00000160185 "Ubiquitin associated and SH3 domain containing A" P57075 21 42403447-42447684 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 17.6" "Cell type enhanced" "Detected in some" "Endometrial secretory cells: 4.5;Erythrocyte progenitors: 6.6;Innate lymphoid cells: 11.0;Megakaryocyte-Erythroid progenitors: 8.9;Megakaryocytes: 18.5;NK-cells: 9.3;T-cells: 47.5;Thymocytes: 5.1" "Cell type enriched" "Detected in single" 546 "leukocyte: 54.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 10 "gdT-cell: 12.9;MAIT T-cell: 23.0;memory CD4 T-cell: 28.3;memory CD8 T-cell: 24.8;naive CD4 T-cell: 32.3;naive CD8 T-cell: 24.1;T-reg: 28.0" "Lineage enriched" "Detected in many" 12 "T-cells: 32.3" "Cancer enriched" "Detected in some" 5 "Leukemia: 9.2" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Minor Salivary Gland - T-cells, Pancreas - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Spleen - T-cells, Stomach - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA049738 Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" 21 Nucleoplasm "Nuclear speckles, Cytosol" "HPA049738: " "unprognostic (1.89e-3)" "unprognostic (8.06e-3)" "unprognostic (2.61e-3)" "unprognostic (6.55e-2)" "unprognostic (3.13e-1)" "unprognostic (7.52e-2)" "unprognostic (1.19e-2)" "potential prognostic favorable (4.64e-4)" "unprognostic (1.43e-1)" "unprognostic (1.02e-1)" "unprognostic (8.49e-3)" "unprognostic (2.48e-1)" "unprognostic (1.21e-1)" "unprognostic (2.18e-1)" "unprognostic (1.57e-1)" UBASH3B "KIAA1959, STS-1, TULA-2, TULA2" ENSG00000154127 "Ubiquitin associated and SH3 domain containing B" Q8TF42 11 122655722-122814473 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.2;lymphoid tissue: 14.7;placenta: 12.9" "Cell type enhanced" "Detected in many" "cDC: 260.6;Cytotrophoblasts: 268.7;Extravillous trophoblasts: 340.5;Hematopoietic stem cells: 280.5;Innate lymphoid cells: 264.2;Megakaryocyte progenitors: 256.8;Megakaryocytes: 247.3;monocytes: 245.2;Neutrophils: 321.3;Schwann cells: 239.4;Syncytiotrophoblasts: 303.9;Thymocytes: 816.5" "Cell type enhanced" "Detected in all" "upper rhombic lip: 448.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038605, HPA038606, HPA038607" Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 150000 "Cluster 25: Non-specific - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 51 Cytosol "Nucleoplasm, Nuclear bodies" "HPA038605: , HPA038606: , HPA038607: " "unprognostic (6.96e-3)" "unprognostic (5.81e-2)" "unprognostic (1.16e-1)" "unprognostic (5.74e-2)" "unprognostic (5.06e-1)" "unprognostic (1.18e-1)" "unprognostic (3.82e-1)" "unprognostic (2.99e-1)" "unprognostic (1.11e-1)" "unprognostic (2.44e-2)" "unprognostic (2.75e-1)" "unprognostic (2.28e-1)" "unprognostic (2.80e-1)" "unprognostic (1.08e-1)" "unprognostic (2.59e-2)" "unprognostic (2.17e-3)" "unprognostic (1.48e-2)" "unprognostic (3.31e-1)" "unprognostic (1.02e-1)" "potential prognostic unfavorable (1.44e-4)" "unprognostic (7.87e-2)" "unprognostic (2.18e-2)" "unprognostic (6.33e-2)" "unprognostic (9.98e-2)" "unprognostic (1.46e-1)" "unprognostic (1.54e-2)" "unprognostic (1.80e-3)" "unprognostic (4.42e-1)" UBB "FLJ25987, MGC8385" ENSG00000170315 "Ubiquitin B" P0CG47 17 16380798-16382745 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 3300.5;Erythrocytes: 3169.8;Late primary spermatocytes: 5880.7;Late spermatids: 2725.7;Oocytes: 3016.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013048, HPA041344, HPA049132" Supported Uncertain "Cytosol,Acrosome,Equatorial segment" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 89 Cytosol "Acrosome, Equatorial segment" "CAB013048: , HPA041344: , HPA049132: " "unprognostic (4.96e-2)" "unprognostic (4.68e-2)" "unprognostic (4.61e-3)" "unprognostic (6.43e-2)" "unprognostic (1.65e-1)" "unprognostic (3.91e-2)" "unprognostic (4.83e-1)" "unprognostic (5.30e-2)" "unprognostic (1.26e-1)" "potential prognostic unfavorable (4.46e-4)" "potential prognostic favorable (6.13e-8)" "unprognostic (1.87e-3)" "unprognostic (8.52e-2)" "unprognostic (2.40e-2)" "unprognostic (1.88e-1)" "unprognostic (1.62e-1)" "unprognostic (3.16e-1)" "unprognostic (4.12e-3)" "unprognostic (3.28e-1)" "potential prognostic favorable (2.22e-4)" "unprognostic (1.20e-1)" "potential prognostic favorable (2.94e-4)" "unprognostic (4.13e-1)" "unprognostic (1.48e-2)" "unprognostic (3.48e-2)" "unprognostic (5.60e-2)" "unprognostic (3.14e-2)" "unprognostic (1.21e-1)" "unprognostic (2.98e-1)" "unprognostic (1.45e-1)" "unprognostic (8.30e-2)" UBC ENSG00000150991 "Ubiquitin C" P0CG48 12 124911604-124917368 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 4803.4;Esophageal apical cells: 12836.8;Late spermatids: 5575.0" "Cell type enhanced" "Detected in all" "endothelial cell: 676.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000362, CAB005419, HPA041344, HPA049132" Supported Uncertain "Cytosol,Acrosome,Equatorial segment" NA Yes "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 84: Apical squamous epithelium - Cornification" 561 Cytosol "Acrosome, Equatorial segment" "CAB000362: , CAB005419: , HPA041344: , HPA049132: " "unprognostic (2.35e-3)" "unprognostic (1.04e-1)" "unprognostic (4.55e-1)" "unprognostic (2.96e-2)" "unprognostic (9.02e-2)" "unprognostic (1.37e-2)" "unprognostic (3.73e-2)" "unprognostic (3.35e-2)" "unprognostic (1.86e-1)" "unprognostic (1.58e-1)" "unprognostic (4.88e-3)" "unprognostic (2.23e-2)" "unprognostic (1.89e-2)" "potential prognostic unfavorable (5.94e-4)" "unprognostic (3.21e-3)" "unprognostic (6.40e-3)" "unprognostic (4.79e-3)" "unprognostic (1.40e-1)" "unprognostic (2.32e-1)" "unprognostic (1.85e-2)" "unprognostic (5.88e-2)" "unprognostic (4.92e-2)" "unprognostic (8.08e-2)" "unprognostic (1.64e-1)" "unprognostic (2.94e-1)" "unprognostic (2.65e-2)" "unprognostic (1.37e-3)" "unprognostic (5.20e-2)" "unprognostic (6.24e-2)" "unprognostic (4.47e-2)" "unprognostic (1.57e-2)" UBD FAT10 ENSG00000213886 "Ubiquitin D" O15205 6 29555515-29559732 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 141.8" "Cell type enhanced" "Detected in some" "Cholangiocytes: 2.0;Gastric progenitor cells: 1.3;Pancreatic duct cells: 1.7;Respiratory deuterosomal cells: 2.1;Submucosal glandular cells: 1.3" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 22.4;thyroid cancer: 44.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA043710 Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 82: Dendritic cells - Antigen presentation" 22 Nucleoplasm "Nucleoli fibrillar center" "HPA043710: " "potential prognostic favorable (7.09e-5)" "unprognostic (3.93e-3)" "unprognostic (2.42e-1)" "potential prognostic favorable (3.70e-4)" "potential prognostic favorable (3.67e-4)" "unprognostic (2.62e-3)" "unprognostic (7.73e-3)" "unprognostic (3.93e-1)" "unprognostic (1.50e-1)" "unprognostic (1.31e-1)" "unprognostic (3.29e-2)" "unprognostic (1.43e-2)" "unprognostic (1.50e-2)" "unprognostic (1.23e-2)" "unprognostic (1.25e-1)" "unprognostic (4.25e-3)" "unprognostic (2.60e-1)" "potential prognostic favorable (4.37e-4)" "unprognostic (1.73e-1)" "unprognostic (6.18e-3)" "unprognostic (1.66e-2)" "unprognostic (1.16e-1)" "unprognostic (6.53e-2)" "unprognostic (5.01e-2)" "unprognostic (1.54e-2)" "potential prognostic favorable (1.02e-4)" "unprognostic (7.58e-2)" "unprognostic (1.70e-1)" "unprognostic (2.05e-1)" "unprognostic (1.15e-1)" "unprognostic (2.00e-1)" UBE2A "HHR6A, HR6A, RAD6A, UBC2" ENSG00000077721 "Ubiquitin conjugating enzyme E2 A" P49459 X 119474802-119591083 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Chromatin regulator, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 550.6;Syncytiotrophoblasts: 696.7;Thyrotrophs: 489.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003875, HPA051765, HPA065898" Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol,Flagellar centriole,Mid piece,Principal piece" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 51 "Nucleoplasm, Plasma membrane, Cytosol" "Vesicles, Flagellar centriole, Mid piece, Principal piece" "HPA003875: , HPA051765: , HPA065898: " "unprognostic (2.10e-1)" "potential prognostic unfavorable (2.69e-5)" "unprognostic (1.30e-2)" "unprognostic (8.77e-2)" "unprognostic (1.59e-1)" "unprognostic (9.61e-2)" "unprognostic (2.32e-1)" "unprognostic (1.96e-1)" "unprognostic (3.18e-3)" "unprognostic (1.12e-3)" "potential prognostic favorable (5.36e-6)" "unprognostic (1.54e-2)" "unprognostic (1.38e-3)" "unprognostic (2.88e-3)" "unprognostic (7.27e-2)" "unprognostic (4.84e-2)" "unprognostic (3.11e-3)" "unprognostic (3.51e-1)" "unprognostic (7.06e-2)" "unprognostic (1.98e-1)" "unprognostic (9.63e-2)" "unprognostic (4.76e-2)" "unprognostic (3.38e-2)" "unprognostic (1.60e-1)" "unprognostic (4.01e-1)" "unprognostic (8.09e-2)" "unprognostic (7.07e-2)" "unprognostic (1.80e-1)" "unprognostic (8.25e-2)" "unprognostic (1.78e-1)" "unprognostic (3.52e-1)" UBE2B "HHR6B, RAD6B, UBC2" ENSG00000119048 "Ubiquitin conjugating enzyme E2 B" P63146 5 134371184-134392108 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 202.4" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1342.4;Neutrophils: 1754.2;Syncytiotrophoblasts: 1179.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 312.6" "Lineage enriched" "Detected in all" 6 "granulocytes: 312.6" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003875, HPA051765, HPA065898" Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol,Flagellar centriole,Mid piece,Principal piece" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 31: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 27 "Nucleoplasm, Plasma membrane, Cytosol" "Vesicles, Flagellar centriole, Mid piece, Principal piece" "HPA003875: , HPA051765: , HPA065898: " "unprognostic (4.54e-2)" "unprognostic (1.09e-2)" "unprognostic (1.00e-1)" "unprognostic (1.82e-1)" "unprognostic (9.53e-2)" "unprognostic (1.79e-1)" "unprognostic (3.86e-3)" "unprognostic (3.00e-1)" "unprognostic (1.52e-2)" "unprognostic (5.21e-1)" "validated prognostic favorable (8.17e-9)" "validated prognostic favorable (8.46e-6)" "unprognostic (2.81e-1)" "unprognostic (8.13e-2)" "unprognostic (3.53e-1)" "unprognostic (2.47e-1)" "unprognostic (5.53e-2)" "unprognostic (1.26e-3)" "unprognostic (2.87e-3)" "unprognostic (2.19e-1)" "potential prognostic unfavorable (4.46e-4)" "unprognostic (2.77e-3)" "potential prognostic unfavorable (2.64e-4)" "unprognostic (7.37e-2)" "unprognostic (2.17e-2)" "unprognostic (3.67e-2)" "unprognostic (2.42e-1)" "unprognostic (1.66e-2)" "unprognostic (1.13e-1)" "unprognostic (7.44e-2)" "unprognostic (1.69e-1)" UBE2C UBCH10 ENSG00000175063 "Ubiquitin conjugating enzyme E2 C" O00762 20 45812576-45816957 "Cancer-related genes, Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 74.0;lymphoid tissue: 105.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 134.4;Enteric transient amplifying cells: 232.5;Esophageal basal cells: 179.4;Extravillous trophoblasts: 511.3;Gastric progenitor cells: 528.0;Hofbauer cells: 143.6;Megakaryocyte progenitors: 337.6;Megakaryocytes: 680.0;Migrating cytotrophoblasts: 260.1;Monocyte progenitors: 158.8;Oocytes: 497.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "T-reg: 8.2" "Group enriched" "Detected in many" 5 "granulocytes: 2.1;NK-cells: 2.1;T-cells: 8.2" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Thyroid gland - Mitotic cells (Thyroid)" "Group enriched" "Detected in many" 5 "basal ganglia: 4.3;white matter: 11.5" "Low region specificity" "Detected in many" "CAB011464, HPA034569, CAB035990, HPA054975, CAB080407" Approved Supported "Plasma membrane,Cytosol" Yes Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 48: Non-specific - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 27: Non-specific - Cell proliferation" 15 "Plasma membrane, Cytosol" "CAB011464: , CAB035990: , CAB080407: , HPA034569: , HPA054975: " "unprognostic (3.63e-2)" "unprognostic (1.90e-2)" "unprognostic (1.01e-1)" "unprognostic (1.32e-1)" "unprognostic (2.25e-1)" "unprognostic (3.33e-2)" "unprognostic (2.60e-1)" "unprognostic (1.29e-3)" "unprognostic (1.07e-1)" "potential prognostic unfavorable (5.60e-6)" "validated prognostic unfavorable (1.67e-13)" "validated prognostic unfavorable (2.92e-7)" "potential prognostic unfavorable (2.33e-12)" "validated prognostic unfavorable (5.02e-6)" "validated prognostic unfavorable (1.88e-8)" "validated prognostic unfavorable (4.61e-5)" "validated prognostic unfavorable (1.59e-4)" "unprognostic (4.54e-2)" "unprognostic (3.98e-1)" "unprognostic (1.64e-1)" "unprognostic (6.45e-3)" "validated prognostic unfavorable (3.28e-4)" "validated prognostic unfavorable (9.97e-4)" "unprognostic (3.79e-2)" "unprognostic (2.32e-1)" "unprognostic (6.43e-3)" "unprognostic (2.02e-1)" "unprognostic (1.83e-1)" "unprognostic (1.90e-1)" "unprognostic (1.44e-2)" "unprognostic (1.57e-3)" UBE2D1 "E2(17)KB1, SFT, UBC4/5, UBCH5, UbcH5A" ENSG00000072401 "Ubiquitin conjugating enzyme E2 D1" P51668 10 58334979-58370751 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 129.9;tongue: 61.1" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 311.3;monocytes: 275.1;Myonuclei: 310.4;Neutrophil progenitors: 250.4;Neutrophils: 1081.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 112.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Kidney - Endothelial cells, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003920 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 197 "Plasma membrane, Cytosol" "HPA003920: " "unprognostic (6.08e-2)" "unprognostic (1.59e-2)" "unprognostic (8.85e-2)" "unprognostic (4.15e-2)" "unprognostic (3.74e-2)" "unprognostic (1.06e-2)" "unprognostic (1.46e-1)" "potential prognostic favorable (3.10e-4)" "unprognostic (8.50e-2)" "unprognostic (5.76e-2)" "potential prognostic favorable (5.38e-4)" "unprognostic (1.05e-1)" "unprognostic (1.07e-1)" "potential prognostic unfavorable (2.14e-4)" "unprognostic (1.65e-2)" "potential prognostic unfavorable (3.46e-4)" "unprognostic (8.13e-3)" "unprognostic (7.37e-2)" "unprognostic (1.42e-2)" "unprognostic (2.20e-1)" "unprognostic (1.48e-2)" "potential prognostic unfavorable (8.41e-4)" "unprognostic (1.19e-2)" "unprognostic (4.83e-2)" "unprognostic (1.75e-2)" "unprognostic (2.73e-2)" "unprognostic (7.29e-2)" "unprognostic (6.88e-3)" "unprognostic (4.86e-1)" "unprognostic (4.73e-2)" "unprognostic (5.25e-2)" UBE2D2 "UBC4, UbcH5B" ENSG00000131508 "Ubiquitin conjugating enzyme E2 D2" P62837 5 139526431-139628434 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial ciliated cells: 2797.5;Endometrial glandular cells: 2919.2;Endometrial luminal cells: 1480.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003920 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 51: Secretory epithelial cells - Mixed function" 208 "Plasma membrane, Cytosol" "HPA003920: " "unprognostic (1.58e-2)" "unprognostic (1.12e-2)" "potential prognostic unfavorable (3.50e-5)" "unprognostic (1.69e-2)" "potential prognostic favorable (7.65e-5)" "unprognostic (1.38e-1)" "unprognostic (2.81e-2)" "unprognostic (1.28e-1)" "potential prognostic unfavorable (8.97e-4)" "unprognostic (1.66e-2)" "potential prognostic favorable (5.57e-5)" "unprognostic (9.06e-2)" "unprognostic (5.17e-2)" "validated prognostic unfavorable (1.06e-5)" "validated prognostic unfavorable (5.17e-4)" "unprognostic (2.52e-3)" "unprognostic (9.72e-2)" "unprognostic (7.14e-2)" "unprognostic (2.74e-1)" "unprognostic (7.13e-2)" "unprognostic (1.26e-3)" "unprognostic (1.29e-1)" "unprognostic (3.32e-2)" "unprognostic (2.51e-2)" "unprognostic (5.13e-2)" "unprognostic (2.69e-1)" "unprognostic (1.04e-1)" "unprognostic (4.99e-2)" "unprognostic (2.42e-1)" "unprognostic (1.75e-1)" "unprognostic (1.58e-1)" UBE2D3 UbcH5C ENSG00000109332 "Ubiquitin conjugating enzyme E2 D3" P61077 4 102794383-102868896 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1697.9;Neutrophils: 1720.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003920 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 59: Leukemia - T-cell receptor" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 170 "Plasma membrane, Cytosol" "HPA003920: " "unprognostic (6.66e-2)" "unprognostic (1.78e-2)" "unprognostic (4.84e-1)" "unprognostic (9.42e-2)" "unprognostic (1.66e-2)" "unprognostic (2.68e-1)" "unprognostic (3.92e-2)" "unprognostic (2.72e-1)" "unprognostic (9.66e-2)" "unprognostic (2.42e-1)" "validated prognostic favorable (1.94e-9)" "validated prognostic favorable (3.70e-4)" "unprognostic (3.04e-1)" "unprognostic (1.59e-2)" "unprognostic (7.43e-2)" "unprognostic (2.51e-3)" "unprognostic (1.37e-2)" "unprognostic (8.82e-2)" "unprognostic (1.88e-2)" "unprognostic (1.20e-1)" "unprognostic (4.69e-2)" "unprognostic (2.18e-2)" "unprognostic (4.45e-2)" "unprognostic (8.05e-2)" "unprognostic (1.70e-1)" "unprognostic (1.09e-2)" "unprognostic (1.91e-1)" "unprognostic (2.24e-1)" "unprognostic (2.45e-1)" "unprognostic (8.53e-2)" "unprognostic (2.14e-2)" UBE2D4 HBUCE1 ENSG00000078967 "Ubiquitin conjugating enzyme E2 D4 (putative)" Q9Y2X8 7 43926436-43956136 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 30.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 99.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" HPA003920 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 15: Non-specific - Transcription" "Cluster 67: Non-specific - Unknown function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 101 "Plasma membrane, Cytosol" "HPA003920: " "unprognostic (6.07e-3)" "unprognostic (1.29e-1)" "unprognostic (4.39e-1)" "unprognostic (4.43e-1)" "unprognostic (1.95e-2)" "unprognostic (1.09e-1)" "unprognostic (7.76e-2)" "unprognostic (6.13e-2)" "unprognostic (1.68e-1)" "unprognostic (1.30e-2)" "unprognostic (6.51e-3)" "unprognostic (1.37e-1)" "potential prognostic favorable (3.49e-4)" "unprognostic (1.15e-1)" "unprognostic (1.24e-1)" "unprognostic (2.44e-2)" "unprognostic (3.84e-1)" "unprognostic (5.66e-3)" "unprognostic (4.11e-1)" "unprognostic (1.07e-1)" "unprognostic (1.31e-1)" "unprognostic (3.03e-3)" "unprognostic (1.17e-1)" "unprognostic (4.47e-2)" "unprognostic (3.25e-1)" "unprognostic (6.34e-2)" "unprognostic (1.00e-1)" "unprognostic (1.44e-1)" "unprognostic (1.02e-1)" "unprognostic (1.31e-1)" "unprognostic (1.10e-1)" UBE2E1 UbcH6 ENSG00000170142 "Ubiquitin conjugating enzyme E2 E1" P51965 3 23805955-23891640 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030445, CAB073413, CAB080048" Approved Supported Nucleoplasm NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 55: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 68 Nucleoplasm "CAB073413: , CAB080048: , HPA030445: " "unprognostic (2.79e-1)" "unprognostic (3.53e-2)" "unprognostic (1.15e-1)" "unprognostic (3.55e-2)" "unprognostic (1.27e-1)" "unprognostic (2.32e-1)" "unprognostic (1.71e-2)" "unprognostic (8.07e-2)" "unprognostic (6.96e-2)" "potential prognostic unfavorable (1.28e-4)" "potential prognostic favorable (3.71e-5)" "unprognostic (2.23e-1)" "unprognostic (5.36e-2)" "potential prognostic unfavorable (1.17e-11)" "unprognostic (3.25e-3)" "unprognostic (1.60e-2)" "potential prognostic unfavorable (5.44e-4)" "unprognostic (1.43e-1)" "unprognostic (1.13e-1)" "unprognostic (1.39e-2)" "unprognostic (4.44e-2)" "unprognostic (2.07e-2)" "unprognostic (1.12e-3)" "unprognostic (6.39e-2)" "unprognostic (8.01e-2)" "unprognostic (1.65e-1)" "unprognostic (1.17e-1)" "unprognostic (1.85e-1)" "unprognostic (1.08e-1)" "unprognostic (1.68e-1)" "unprognostic (4.61e-2)" UBE2E2 "FLJ25157, UbcH8" ENSG00000182247 "Ubiquitin conjugating enzyme E2 E2" Q96LR5 3 23203020-23591794 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 1164.6;Microglia: 1417.6;Myonuclei: 1643.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 41.8;intermediate monocyte: 50.5;memory B-cell: 35.3;myeloid DC: 57.7;naive B-cell: 40.3;non-classical monocyte: 55.0;plasmacytoid DC: 74.3" "Group enriched" "Detected in all" 6 "B-cells: 40.3;dendritic cells: 74.3;monocytes: 55.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003303, HPA028872, HPA030445, CAB073417" Approved Approved Nucleoplasm No No "Cluster 23: B-cells - Immunoglobulins" "Cluster 74: Non-specific - Signal transduction" "Cluster 34: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 61 Nucleoplasm "CAB073417: , HPA003303: , HPA028872: , HPA030445: " "unprognostic (2.31e-1)" "unprognostic (1.75e-1)" "unprognostic (6.30e-3)" "unprognostic (4.41e-2)" "unprognostic (7.17e-2)" "unprognostic (2.54e-1)" "unprognostic (1.14e-1)" "potential prognostic favorable (9.07e-6)" "unprognostic (1.33e-2)" "unprognostic (1.33e-1)" "potential prognostic favorable (4.20e-5)" "unprognostic (2.00e-1)" "unprognostic (2.64e-2)" "unprognostic (1.92e-2)" "unprognostic (1.73e-2)" "unprognostic (1.60e-1)" "unprognostic (1.31e-2)" "potential prognostic unfavorable (8.46e-4)" "unprognostic (1.33e-2)" "unprognostic (1.71e-1)" "unprognostic (2.73e-2)" "unprognostic (8.36e-2)" "unprognostic (2.63e-3)" "unprognostic (2.73e-1)" "unprognostic (3.10e-2)" "unprognostic (1.63e-1)" "unprognostic (7.16e-2)" "unprognostic (4.85e-2)" "unprognostic (2.60e-1)" "unprognostic (1.73e-1)" "unprognostic (3.10e-1)" UBE2E3 UbcH9 ENSG00000170035 "Ubiquitin conjugating enzyme E2 E3" Q969T4 2 180967248-181076585 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Growth regulation, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003303, HPA030445" Approved NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 51: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 77 "HPA003303: , HPA030445: " "unprognostic (9.97e-2)" "unprognostic (1.62e-1)" "unprognostic (1.85e-2)" "unprognostic (2.69e-2)" "unprognostic (1.32e-1)" "unprognostic (4.96e-2)" "unprognostic (3.13e-2)" "potential prognostic favorable (1.43e-4)" "unprognostic (5.02e-2)" "unprognostic (4.34e-1)" "potential prognostic favorable (3.00e-4)" "unprognostic (5.34e-2)" "unprognostic (3.14e-1)" "validated prognostic unfavorable (3.07e-4)" "validated prognostic unfavorable (2.55e-5)" "potential prognostic unfavorable (4.12e-5)" "unprognostic (6.45e-3)" "unprognostic (1.07e-1)" "unprognostic (1.34e-1)" "unprognostic (6.17e-2)" "unprognostic (2.76e-1)" "unprognostic (1.03e-3)" "unprognostic (6.09e-3)" "unprognostic (3.30e-1)" "unprognostic (2.26e-2)" "unprognostic (9.28e-2)" "unprognostic (3.77e-1)" "unprognostic (1.57e-2)" "unprognostic (4.40e-1)" "unprognostic (2.44e-1)" "unprognostic (3.67e-1)" UBE2F NCE2 ENSG00000184182 "Ubiquitin conjugating enzyme E2 F (putative)" Q969M7 2 237966827-238042782 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 31.3;Choroid plexus epithelial cells: 37.5;Extravillous trophoblasts: 37.5;Late spermatids: 57.2;Megakaryocytes: 61.8;Microglia: 84.9;Oligodendrocytes: 47.9;Other brain neurons: 36.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037444 Approved Approved Cytosol NA NA 27000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 22: Non-specific - Basic cellular functions" 9 Cytosol "HPA037444: " "unprognostic (2.19e-1)" "unprognostic (1.25e-3)" "unprognostic (4.63e-2)" "unprognostic (9.01e-3)" "unprognostic (2.31e-1)" "unprognostic (2.30e-2)" "unprognostic (2.18e-1)" "unprognostic (6.88e-3)" "potential prognostic unfavorable (4.87e-4)" "unprognostic (2.33e-1)" "unprognostic (1.03e-1)" "unprognostic (1.57e-1)" "unprognostic (2.00e-2)" "validated prognostic unfavorable (3.01e-8)" "validated prognostic unfavorable (1.38e-5)" "unprognostic (2.26e-3)" "unprognostic (3.36e-2)" "unprognostic (1.29e-1)" "unprognostic (3.49e-1)" "unprognostic (1.97e-1)" "unprognostic (2.93e-1)" "unprognostic (8.29e-2)" "unprognostic (1.27e-2)" "unprognostic (2.44e-1)" "unprognostic (3.00e-3)" "unprognostic (6.89e-3)" "unprognostic (4.24e-1)" "unprognostic (3.22e-3)" "unprognostic (2.20e-1)" "unprognostic (3.93e-1)" "unprognostic (2.31e-1)" UBE2G1 "UBC7, UBE2G" ENSG00000132388 "Ubiquitin conjugating enzyme E2 G1" P62253 17 4269259-4366675 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 190.2" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 751.2;Late spermatids: 412.8;Myonuclei: 834.9;Suprabasal keratinocytes: 406.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Skin - Keratinocyte (other), Spleen - Mitotic cells (Spleen), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045681, HPA050551" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 12 "Nucleoplasm, Cytosol" "HPA045681: , HPA050551: " "unprognostic (1.04e-1)" "potential prognostic unfavorable (6.40e-4)" "unprognostic (1.55e-3)" "unprognostic (2.48e-1)" "unprognostic (4.69e-2)" "unprognostic (3.39e-1)" "unprognostic (5.39e-2)" "unprognostic (1.62e-2)" "unprognostic (3.27e-2)" "unprognostic (1.13e-3)" "potential prognostic favorable (3.45e-5)" "unprognostic (1.45e-1)" "unprognostic (1.89e-1)" "unprognostic (6.62e-3)" "unprognostic (8.15e-2)" "unprognostic (1.98e-2)" "unprognostic (3.11e-1)" "unprognostic (8.12e-2)" "unprognostic (2.97e-1)" "unprognostic (2.33e-1)" "unprognostic (6.50e-3)" "unprognostic (1.06e-1)" "unprognostic (4.54e-2)" "unprognostic (3.51e-2)" "unprognostic (2.88e-1)" "unprognostic (2.78e-1)" "unprognostic (2.77e-2)" "unprognostic (2.28e-1)" "unprognostic (4.03e-2)" "unprognostic (1.70e-2)" "unprognostic (3.10e-1)" UBE2G2 UBC7 ENSG00000184787 "Ubiquitin conjugating enzyme E2 G2" P60604 21 44768580-44801826 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 308.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003332 Approved NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cellular respiration" "Cluster 45: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 17: Non-specific - RNA processing" 17 "HPA003332: " "unprognostic (8.22e-3)" "unprognostic (3.35e-2)" "unprognostic (6.09e-3)" "unprognostic (5.87e-2)" "unprognostic (1.86e-1)" "unprognostic (9.95e-2)" "unprognostic (7.39e-2)" "unprognostic (1.01e-2)" "unprognostic (3.76e-2)" "unprognostic (2.03e-1)" "potential prognostic favorable (1.76e-6)" "unprognostic (9.17e-2)" "unprognostic (6.75e-3)" "unprognostic (1.53e-1)" "unprognostic (3.88e-2)" "unprognostic (2.95e-1)" "unprognostic (3.29e-1)" "unprognostic (1.71e-1)" "unprognostic (1.87e-1)" "unprognostic (7.34e-3)" "unprognostic (4.22e-1)" "unprognostic (2.47e-1)" "unprognostic (9.27e-2)" "unprognostic (1.27e-1)" "unprognostic (2.44e-1)" "unprognostic (2.34e-2)" "unprognostic (8.43e-2)" "unprognostic (2.12e-1)" "unprognostic (1.61e-1)" "unprognostic (8.77e-3)" "unprognostic (1.14e-1)" UBE2H "GID3, UBC8, UBCH" ENSG00000186591 "Ubiquitin conjugating enzyme E2 H" P62256 7 129830732-129952960 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial glandular cells: 2954.7;Endometrial luminal cells: 1592.5;Neutrophils: 1916.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003302 Approved Approved Mitochondria NA NA 34000 "Cluster 24: Non-specific - Transcription" "Cluster 76: Non-specific - Metabolism" "Cluster 55: Non-specific - Transcription" "Cluster 39: Non-specific - Transcription" "Cluster 51: Secretory epithelial cells - Mixed function" 43 Mitochondria "HPA003302: " "unprognostic (1.04e-2)" "unprognostic (5.54e-2)" "unprognostic (2.92e-2)" "unprognostic (1.76e-2)" "unprognostic (4.42e-2)" "unprognostic (8.70e-3)" "unprognostic (2.27e-1)" "unprognostic (1.10e-1)" "unprognostic (4.09e-2)" "unprognostic (2.54e-3)" "unprognostic (1.62e-3)" "unprognostic (1.43e-1)" "unprognostic (6.48e-2)" "unprognostic (4.44e-2)" "unprognostic (1.42e-2)" "unprognostic (2.41e-3)" "potential prognostic unfavorable (9.16e-4)" "unprognostic (5.97e-2)" "unprognostic (2.58e-1)" "unprognostic (2.43e-3)" "unprognostic (2.65e-1)" "potential prognostic unfavorable (2.44e-4)" "unprognostic (2.85e-1)" "unprognostic (5.09e-2)" "unprognostic (1.67e-1)" "unprognostic (2.49e-1)" "unprognostic (2.78e-1)" "unprognostic (2.85e-1)" "unprognostic (3.15e-1)" "unprognostic (1.11e-1)" "unprognostic (1.74e-2)" UBE2I UBC9 ENSG00000103275 "Ubiquitin conjugating enzyme E2 I" P63279 16 1308880-1327018 "Cancer-related genes, Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Chromosome partition, Host-virus interaction, Mitosis, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 492.7;Syncytiotrophoblasts: 496.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003909, CAB009021, CAB079920" Approved Supported Nucleoplasm,Nucleoli NA NA 170000 "Cluster 41: Basophils - Unknown function" "Cluster 49: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 54: Non-specific - Transcription" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 248 Nucleoplasm Nucleoli "CAB009021: , CAB079920: , HPA003909: " "unprognostic (1.23e-1)" "unprognostic (5.78e-2)" "unprognostic (1.55e-1)" "unprognostic (1.33e-1)" "unprognostic (9.24e-2)" "unprognostic (8.78e-2)" "unprognostic (1.49e-1)" "unprognostic (1.58e-1)" "unprognostic (2.61e-1)" "unprognostic (1.98e-1)" "unprognostic (2.28e-2)" "unprognostic (1.53e-1)" "unprognostic (1.30e-2)" "potential prognostic unfavorable (6.39e-6)" "unprognostic (1.12e-3)" "unprognostic (1.14e-3)" "unprognostic (1.79e-2)" "unprognostic (5.17e-2)" "unprognostic (2.71e-1)" "unprognostic (5.59e-2)" "unprognostic (3.82e-1)" "validated prognostic unfavorable (5.37e-4)" "validated prognostic unfavorable (3.42e-7)" "unprognostic (1.19e-1)" "unprognostic (4.12e-2)" "unprognostic (7.74e-2)" "unprognostic (1.26e-1)" "unprognostic (3.68e-1)" "unprognostic (1.58e-1)" "unprognostic (1.52e-2)" "unprognostic (4.26e-2)" UBE2J1 "CGI-76, HSPC153, NCUBE1, UBC6" ENSG00000198833 "Ubiquitin conjugating enzyme E2 J1" Q9Y385 6 89326625-89352722 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 615.9;Late spermatids: 2044.0;Neutrophils: 523.8;Plasma cells: 780.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Myeloma: 226.1" "Kidney - Endothelial cells, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003509, CAB073419" Enhanced NA NA 27000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 55: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 67: Plasma cells - Plasma cell differentiation" 61 "CAB073419: , HPA003509: " "unprognostic (1.76e-2)" "unprognostic (2.36e-1)" "unprognostic (1.29e-1)" "unprognostic (3.42e-3)" "unprognostic (4.85e-3)" "unprognostic (1.36e-2)" "unprognostic (1.30e-1)" "unprognostic (2.36e-1)" "unprognostic (1.52e-2)" "unprognostic (7.61e-3)" "potential prognostic favorable (9.26e-4)" "unprognostic (1.64e-2)" "unprognostic (8.49e-3)" "unprognostic (3.75e-3)" "unprognostic (3.06e-2)" "unprognostic (8.19e-2)" "unprognostic (2.75e-1)" "unprognostic (7.91e-3)" "unprognostic (4.18e-2)" "unprognostic (1.64e-3)" "unprognostic (1.60e-2)" "unprognostic (1.85e-1)" "unprognostic (7.37e-2)" "unprognostic (1.32e-1)" "unprognostic (4.35e-2)" "unprognostic (2.08e-1)" "unprognostic (1.60e-1)" "unprognostic (1.34e-1)" "unprognostic (3.85e-1)" "unprognostic (2.00e-1)" "unprognostic (1.55e-1)" UBE2J2 "NCUBE2, Ubc6p" ENSG00000160087 "Ubiquitin conjugating enzyme E2 J2" Q8N2K1 1 1253909-1273864 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway, Unfolded protein response" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 218.0;Late primary spermatocytes: 452.6;Late spermatids: 633.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 67: Testis - Mixed function" "Cluster 25: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 17 "unprognostic (4.50e-1)" "unprognostic (1.32e-1)" "unprognostic (1.72e-2)" "unprognostic (1.46e-1)" "unprognostic (2.69e-3)" "unprognostic (1.81e-1)" "unprognostic (3.68e-1)" "unprognostic (1.77e-3)" "unprognostic (2.46e-1)" "unprognostic (6.72e-2)" "unprognostic (2.25e-1)" "unprognostic (4.68e-3)" "unprognostic (2.78e-2)" "validated prognostic unfavorable (1.27e-4)" "validated prognostic unfavorable (3.46e-5)" "unprognostic (2.29e-2)" "unprognostic (1.32e-1)" "unprognostic (2.75e-1)" "unprognostic (3.23e-2)" "unprognostic (2.63e-1)" "unprognostic (1.58e-1)" "unprognostic (2.12e-2)" "unprognostic (3.40e-2)" "unprognostic (3.41e-1)" "unprognostic (6.52e-2)" "unprognostic (8.32e-2)" "unprognostic (4.27e-2)" "unprognostic (9.55e-2)" "unprognostic (1.24e-1)" "unprognostic (1.56e-2)" "unprognostic (8.64e-2)" UBE2K "HIP2, HYPG, UBC1" ENSG00000078140 "Ubiquitin conjugating enzyme E2 K" P61086 4 39698109-39782792 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028869, CAB033212, CAB033515" Supported Approved "Plasma membrane,Cytosol" NA NA 270000 "Cluster 13: Non-specific - Mitochondria" "Cluster 76: Non-specific - Metabolism" "Cluster 16: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 7: Non-specific - Transcription" 117 Cytosol "Plasma membrane" "CAB033212: , CAB033515: , HPA028869: " "unprognostic (2.15e-1)" "unprognostic (2.84e-2)" "unprognostic (1.07e-1)" "unprognostic (1.51e-3)" "unprognostic (2.62e-3)" "unprognostic (2.51e-2)" "unprognostic (1.51e-1)" "unprognostic (2.04e-1)" "unprognostic (1.59e-1)" "unprognostic (2.61e-3)" "validated prognostic favorable (8.76e-6)" "validated prognostic favorable (4.60e-5)" "unprognostic (2.28e-1)" "unprognostic (5.43e-3)" "unprognostic (7.51e-3)" "potential prognostic unfavorable (1.80e-4)" "unprognostic (2.40e-2)" "unprognostic (3.62e-2)" "unprognostic (1.65e-1)" "unprognostic (4.54e-2)" "unprognostic (1.49e-1)" "unprognostic (1.63e-3)" "unprognostic (1.71e-2)" "unprognostic (1.25e-2)" "unprognostic (8.77e-2)" "unprognostic (5.09e-3)" "unprognostic (9.71e-2)" "unprognostic (3.27e-2)" "unprognostic (2.78e-1)" "unprognostic (1.61e-1)" "unprognostic (1.61e-1)" UBE2L3 UBCH7 ENSG00000185651 "Ubiquitin conjugating enzyme E2 L3" P68036 22 21549447-21624034 "Enzymes, Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045609, HPA062415" Approved Approved "Nucleoplasm,Primary cilium transition zone,Cytosol" NA NA 5400000 "Cluster 29: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 66: Non-specific - Mitochondria" "Cluster 97: Non-specific - Cellular respiration" 81 "Nucleoplasm, Cytosol" "Primary cilium transition zone" "HPA045609: , HPA062415: " "unprognostic (4.11e-2)" "unprognostic (2.17e-2)" "unprognostic (2.33e-1)" "unprognostic (2.65e-2)" "unprognostic (3.89e-2)" "unprognostic (3.36e-2)" "unprognostic (1.14e-1)" "unprognostic (1.59e-1)" "potential prognostic unfavorable (8.31e-4)" "unprognostic (2.73e-1)" "unprognostic (2.93e-3)" "unprognostic (1.48e-2)" "unprognostic (5.70e-2)" "validated prognostic unfavorable (1.83e-7)" "validated prognostic unfavorable (2.77e-4)" "unprognostic (5.37e-3)" "unprognostic (8.18e-3)" "unprognostic (1.82e-1)" "unprognostic (3.04e-2)" "unprognostic (8.33e-3)" "unprognostic (1.74e-1)" "unprognostic (3.24e-3)" "unprognostic (7.58e-2)" "unprognostic (9.55e-3)" "unprognostic (2.52e-1)" "unprognostic (1.87e-1)" "unprognostic (1.89e-1)" "unprognostic (5.43e-2)" "unprognostic (2.01e-1)" "unprognostic (2.82e-1)" "unprognostic (3.22e-1)" UBE2L5 UBE2L5P ENSG00000236444 "Ubiquitin conjugating enzyme E2 L5" A0A1B0GUS4 13 30422488-30429758 "Enzymes, Essential proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Ligase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 52 "testis: 43.1" "Cell type enriched" "Detected in some" 6 "Late primary spermatocytes: 327.9" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "HPA045609, HPA062415" Approved Approved "Nucleoplasm,Primary cilium transition zone,Cytosol" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 53: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" "Nucleoplasm, Cytosol" "Primary cilium transition zone" "HPA045609: , HPA062415: " UBE2L6 UBCH8 ENSG00000156587 "Ubiquitin conjugating enzyme E2 L6" O14933 11 57551656-57568284 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 253.7;Esophageal basal cells: 106.0;Esophageal suprabasal cells: 102.3;Hofbauer cells: 195.8" "Cell type enhanced" "Detected in all" "endothelial cell: 30.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003328, CAB073407" Enhanced Approved Cytosol NA NA 11000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 44: Non-specific - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 40 Cytosol "CAB073407: , HPA003328: " "unprognostic (1.70e-1)" "potential prognostic favorable (1.21e-4)" "unprognostic (2.61e-1)" "unprognostic (2.14e-1)" "unprognostic (4.52e-1)" "unprognostic (1.53e-1)" "unprognostic (2.38e-1)" "unprognostic (3.44e-2)" "unprognostic (5.04e-1)" "unprognostic (5.20e-2)" "potential prognostic favorable (1.83e-4)" "unprognostic (1.15e-1)" "unprognostic (2.52e-2)" "unprognostic (2.17e-2)" "unprognostic (7.97e-3)" "unprognostic (1.45e-3)" "unprognostic (1.03e-2)" "unprognostic (1.83e-1)" "unprognostic (1.30e-3)" "unprognostic (1.82e-3)" "unprognostic (1.26e-1)" "potential prognostic unfavorable (1.79e-4)" "unprognostic (1.15e-1)" "unprognostic (2.49e-2)" "unprognostic (7.69e-2)" "unprognostic (3.36e-2)" "unprognostic (1.50e-2)" "unprognostic (8.84e-2)" "unprognostic (5.09e-2)" "unprognostic (6.84e-2)" "unprognostic (8.57e-2)" UBE2M "hUbc12, UBC12" ENSG00000130725 "Ubiquitin conjugating enzyme E2 M" P61081 19 58555712-58558954 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004993, HPA054551, HPA057800" Approved Enhanced "Nucleoplasm,Nucleoli,Nuclear bodies,Cytosol" Yes No 39000 "Cluster 7: Non-specific - Innate immune response" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 4: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 83 Nucleoplasm "Nucleoli, Nuclear bodies, Cytosol" "CAB004993: , HPA054551: , HPA057800: " "unprognostic (3.18e-2)" "unprognostic (1.67e-1)" "unprognostic (7.91e-2)" "unprognostic (2.07e-2)" "unprognostic (7.58e-2)" "unprognostic (1.54e-1)" "unprognostic (1.60e-1)" "unprognostic (1.78e-2)" "unprognostic (2.41e-3)" "unprognostic (3.70e-2)" "potential prognostic favorable (4.22e-4)" "unprognostic (6.25e-2)" "unprognostic (7.17e-3)" "validated prognostic unfavorable (1.82e-5)" "validated prognostic unfavorable (6.79e-7)" "unprognostic (1.99e-3)" "unprognostic (1.13e-1)" "unprognostic (3.90e-3)" "unprognostic (3.51e-2)" "unprognostic (8.50e-2)" "unprognostic (3.36e-2)" "unprognostic (5.04e-3)" "unprognostic (2.61e-1)" "unprognostic (1.32e-1)" "unprognostic (3.33e-1)" "unprognostic (4.69e-2)" "unprognostic (2.54e-1)" "unprognostic (1.88e-1)" "unprognostic (1.83e-1)" "unprognostic (1.04e-1)" "unprognostic (2.06e-1)" UBE2N "MGC8489, UBC13, UbcH-ben" ENSG00000177889 "Ubiquitin conjugating enzyme E2 N" P61088 12 93405673-93441947 "Cancer-related genes, Enzymes, Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Late spermatids: 13825.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" HPA044976 Supported Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA 1900000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 39: Testis - Nuclear processes" "Cluster 14: Neurons - Synaptic function" "Cluster 38: Non-specific - Transcription" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 111 Nucleoplasm "Nucleoli fibrillar center" "HPA044976: " "unprognostic (5.35e-2)" "unprognostic (1.62e-2)" "unprognostic (8.62e-3)" "unprognostic (2.95e-2)" "potential prognostic favorable (4.46e-5)" "unprognostic (2.74e-2)" "unprognostic (2.13e-1)" "unprognostic (3.25e-1)" "unprognostic (5.68e-2)" "unprognostic (1.73e-1)" "potential prognostic favorable (1.68e-7)" "unprognostic (4.89e-2)" "unprognostic (4.76e-2)" "validated prognostic unfavorable (2.68e-4)" "validated prognostic unfavorable (2.59e-5)" "unprognostic (2.44e-3)" "unprognostic (5.60e-2)" "unprognostic (1.37e-1)" "unprognostic (2.11e-1)" "unprognostic (1.23e-1)" "unprognostic (1.17e-2)" "unprognostic (1.45e-2)" "unprognostic (1.52e-2)" "unprognostic (9.88e-2)" "unprognostic (4.63e-2)" "unprognostic (6.39e-2)" "unprognostic (2.17e-1)" "unprognostic (3.04e-1)" "unprognostic (2.96e-1)" "unprognostic (1.70e-2)" "unprognostic (1.33e-1)" UBE2NL ENSG00000276380 "Ubiquitin conjugating enzyme E2 N like (gene/pseudogene)" X 143884071-143885255 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Late spermatids: 3.1;Megakaryocytes: 6.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA044976 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 61: BICR 18 - Protein kinases" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 1 Nucleoplasm "Nucleoli fibrillar center" "HPA044976: " UBE2O E2-230K ENSG00000175931 "Ubiquitin conjugating enzyme E2 O" Q9C0C9 17 76389456-76453152 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" "Transport, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Retinal ganglion cells: 193.1;Retinal horizontal cells: 164.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023605 Uncertain Supported "Nucleoplasm,Nuclear bodies" No No 450000 "Cluster 18: Non-specific - Translation" "Cluster 24: Non-specific - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 109: Neurons - Neuronal signaling" 144 "Nuclear bodies" Nucleoplasm "HPA023605: " "unprognostic (3.85e-1)" "unprognostic (7.96e-2)" "unprognostic (1.55e-1)" "unprognostic (1.95e-2)" "unprognostic (1.10e-1)" "unprognostic (2.70e-3)" "unprognostic (1.97e-1)" "unprognostic (4.24e-2)" "unprognostic (4.07e-2)" "unprognostic (1.22e-2)" "unprognostic (1.74e-1)" "unprognostic (2.20e-1)" "unprognostic (2.35e-2)" "validated prognostic unfavorable (1.00e-6)" "validated prognostic unfavorable (4.13e-4)" "unprognostic (1.19e-1)" "potential prognostic unfavorable (9.15e-5)" "unprognostic (1.08e-1)" "unprognostic (4.89e-3)" "unprognostic (5.75e-2)" "unprognostic (6.02e-2)" "unprognostic (4.98e-3)" "unprognostic (4.36e-2)" "unprognostic (9.81e-3)" "unprognostic (4.53e-2)" "unprognostic (1.33e-2)" "unprognostic (1.61e-1)" "unprognostic (2.02e-1)" "unprognostic (3.31e-1)" "unprognostic (7.60e-2)" "unprognostic (5.27e-2)" UBE2Q1 "NICE-5, PRO3094, UBE2Q" ENSG00000160714 "Ubiquitin conjugating enzyme E2 Q1" Q7Z7E8 1 154548577-154559028 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063368 Approved Approved Nucleoplasm,Centrosome,Cytosol No No "Cluster 41: Basophils - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 1: Neurons - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 5 Nucleoplasm "Centrosome, Cytosol" "HPA063368: " "unprognostic (8.51e-2)" "unprognostic (1.13e-2)" "unprognostic (3.90e-1)" "unprognostic (9.41e-3)" "unprognostic (1.41e-1)" "unprognostic (1.98e-3)" "unprognostic (2.09e-1)" "unprognostic (5.52e-2)" "unprognostic (1.53e-2)" "unprognostic (2.13e-2)" "unprognostic (1.08e-1)" "unprognostic (4.86e-3)" "unprognostic (3.11e-2)" "unprognostic (1.50e-3)" "unprognostic (2.26e-1)" "unprognostic (2.74e-2)" "unprognostic (1.04e-1)" "unprognostic (1.17e-2)" "unprognostic (2.25e-1)" "unprognostic (6.12e-2)" "unprognostic (2.47e-2)" "unprognostic (1.46e-1)" "unprognostic (5.37e-2)" "unprognostic (2.21e-1)" "unprognostic (6.86e-3)" "unprognostic (4.59e-3)" "unprognostic (3.32e-1)" "unprognostic (3.55e-1)" "unprognostic (1.26e-1)" "unprognostic (2.69e-2)" "unprognostic (1.96e-2)" UBE2Q2 DKFZp762C143 ENSG00000140367 "Ubiquitin conjugating enzyme E2 Q2" Q8WVN8 15 75843307-75901078 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 356.1;Rod photoreceptor cells: 243.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 40: Non-specific - Mixed function" "Cluster 27: Non-specific - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 79: Photoreceptor cells - Phototransduction" 5 "unprognostic (2.68e-2)" "unprognostic (8.56e-2)" "unprognostic (6.59e-3)" "unprognostic (2.89e-2)" "unprognostic (2.20e-1)" "unprognostic (5.59e-2)" "unprognostic (1.08e-1)" "unprognostic (2.90e-1)" "unprognostic (1.24e-1)" "unprognostic (3.61e-1)" "potential prognostic favorable (5.14e-5)" "unprognostic (7.48e-2)" "unprognostic (4.31e-1)" "potential prognostic unfavorable (7.40e-4)" "unprognostic (2.13e-2)" "unprognostic (1.94e-2)" "unprognostic (5.51e-3)" "unprognostic (6.90e-2)" "unprognostic (3.14e-1)" "unprognostic (1.26e-2)" "unprognostic (7.70e-3)" "unprognostic (3.14e-1)" "unprognostic (8.02e-2)" "unprognostic (3.85e-1)" "unprognostic (7.30e-3)" "unprognostic (5.61e-1)" "unprognostic (1.18e-1)" "unprognostic (4.21e-3)" "unprognostic (2.58e-1)" "unprognostic (2.42e-2)" "unprognostic (5.26e-1)" UBE2QL1 FLJ25076 ENSG00000215218 "Ubiquitin conjugating enzyme E2 Q family like 1" A1L167 5 6448859-6496723 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 33.7;heart muscle: 11.2;retina: 26.3;skeletal muscle: 37.8;tongue: 13.0" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 54.5;Cardiomyocytes: 40.8;Cone photoreceptor cells: 80.7;Myonuclei: 58.3;Pancreatic islet cells: 59.0;Renal collecting duct intercalated cells: 134.6;Retinal bipolar cells: 42.0;Retinal horizontal cells: 54.1;Rod photoreceptor cells: 192.8;Thyrotrophs: 39.7" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 20.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 15.8;Neuroblastoma: 6.0" "Heart muscle - Cardiomyocytes, Kidney - Intercalated cells, Pancreas - Alpha cells, Prostate - Smooth muscle cells, Skin - Sebaceous gland cells, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057414 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 20: Myeloma - Immune response" "Cluster 79: Photoreceptor cells - Phototransduction" Nucleoplasm "Plasma membrane" "HPA057414: " "unprognostic (7.32e-3)" "unprognostic (3.03e-3)" "unprognostic (3.66e-2)" "unprognostic (1.55e-3)" "unprognostic (1.89e-3)" "potential prognostic favorable (1.98e-5)" "unprognostic (3.90e-2)" "unprognostic (2.39e-1)" "unprognostic (1.21e-2)" "unprognostic (8.16e-2)" "unprognostic (1.12e-2)" UBE2R2 "CDC34B, FLJ20419, MGC10481, UBC3B" ENSG00000107341 "Ubiquitin conjugating enzyme E2 R2" Q712K3 9 33817160-33920399 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 1721.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA061000, HPA074334" Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 24: Neutrophils - Innate immunity signal integration" 13 "Nucleoplasm, Nucleoli" Cytosol "HPA061000: , HPA074334: " "unprognostic (1.58e-2)" "unprognostic (1.72e-1)" "unprognostic (4.00e-3)" "unprognostic (8.98e-2)" "unprognostic (2.02e-1)" "potential prognostic unfavorable (7.12e-4)" "unprognostic (1.31e-1)" "unprognostic (3.58e-2)" "unprognostic (7.47e-2)" "unprognostic (6.27e-2)" "potential prognostic favorable (1.54e-6)" "unprognostic (7.48e-3)" "unprognostic (2.04e-1)" "validated prognostic unfavorable (2.61e-4)" "validated prognostic unfavorable (3.00e-4)" "unprognostic (1.02e-3)" "potential prognostic unfavorable (4.65e-4)" "unprognostic (8.45e-2)" "unprognostic (7.86e-2)" "unprognostic (7.39e-2)" "unprognostic (3.60e-2)" "potential prognostic unfavorable (6.60e-4)" "unprognostic (3.40e-1)" "unprognostic (2.75e-1)" "unprognostic (6.59e-2)" "unprognostic (7.82e-2)" "unprognostic (1.59e-1)" "unprognostic (4.67e-2)" "unprognostic (1.88e-1)" "unprognostic (5.69e-2)" "unprognostic (4.81e-2)" UBE2S E2-EPF ENSG00000108106 "Ubiquitin conjugating enzyme E2 S" Q16763 19 55399745-55407788 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 109.2;testis: 146.2" "Cell type enhanced" "Detected in many" "Breast secretory cells: 296.6;Differentiating spermatogonia: 213.4;Innate lymphoid cells: 194.8;pDCs: 297.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015228, HPA057150" Approved Approved "Nucleoplasm,Plasma membrane" NA Yes "Cluster 45: Eosinophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 14: Neurons - Synaptic function" "Cluster 4: Non-specific - Transcription" "Cluster 20: Non-specific - Transcription regulation" 30 "Plasma membrane" Nucleoplasm "CAB015228: , HPA057150: " "unprognostic (5.26e-3)" "unprognostic (1.56e-2)" "unprognostic (1.36e-2)" "unprognostic (8.13e-3)" "unprognostic (3.01e-2)" "unprognostic (2.04e-2)" "unprognostic (2.35e-1)" "unprognostic (1.03e-1)" "unprognostic (2.81e-2)" "unprognostic (2.15e-2)" "validated prognostic unfavorable (8.45e-7)" "validated prognostic unfavorable (1.85e-5)" "potential prognostic unfavorable (1.46e-8)" "validated prognostic unfavorable (2.80e-8)" "validated prognostic unfavorable (1.27e-6)" "potential prognostic unfavorable (8.35e-5)" "unprognostic (2.25e-2)" "potential prognostic favorable (6.88e-4)" "unprognostic (2.17e-1)" "unprognostic (2.20e-1)" "unprognostic (4.41e-2)" "unprognostic (3.42e-2)" "unprognostic (2.00e-1)" "unprognostic (4.72e-3)" "unprognostic (8.51e-2)" "unprognostic (1.26e-1)" "unprognostic (2.19e-2)" "unprognostic (8.69e-2)" "unprognostic (2.27e-1)" "unprognostic (5.45e-2)" "unprognostic (1.74e-2)" UBE2T "FANCT, HSPC150" ENSG00000077152 "Ubiquitin conjugating enzyme E2 T" Q9NPD8 1 202331544-202341984 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 44.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 88.1;Differentiating spermatogonia: 90.1;Early primary spermatocytes: 137.2;Enteric transient amplifying cells: 69.7;Erythrocyte progenitors: 91.4;Esophageal basal cells: 68.2;Extravillous trophoblasts: 114.3;Gastric progenitor cells: 210.2;Late primary spermatocytes: 123.2;Megakaryocyte progenitors: 74.7;Migrating cytotrophoblasts: 115.0;Oocytes: 133.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA002831 Approved Nucleoplasm,Nucleoli NA Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 14: Neurons - Synaptic function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 27: Non-specific - Cell proliferation" 13 Nucleoli Nucleoplasm "HPA002831: " "unprognostic (1.32e-2)" "unprognostic (3.68e-3)" "unprognostic (2.67e-2)" "unprognostic (2.31e-2)" "unprognostic (3.85e-2)" "unprognostic (9.77e-2)" "unprognostic (4.09e-1)" "unprognostic (1.30e-2)" "unprognostic (1.41e-2)" "unprognostic (4.37e-3)" "potential prognostic unfavorable (4.08e-5)" "unprognostic (1.38e-3)" "potential prognostic unfavorable (9.05e-5)" "validated prognostic unfavorable (4.37e-7)" "validated prognostic unfavorable (4.68e-8)" "potential prognostic unfavorable (4.74e-4)" "unprognostic (6.41e-3)" "unprognostic (8.28e-3)" "unprognostic (8.17e-2)" "unprognostic (1.37e-3)" "unprognostic (8.08e-2)" "potential prognostic unfavorable (5.47e-4)" "unprognostic (1.42e-1)" "unprognostic (9.23e-3)" "unprognostic (1.64e-1)" "unprognostic (6.41e-2)" "unprognostic (2.12e-2)" "unprognostic (2.70e-3)" "unprognostic (1.84e-1)" "unprognostic (9.52e-2)" "unprognostic (8.34e-2)" UBE2U MGC35130 ENSG00000177414 "Ubiquitin conjugating enzyme E2 U" Q5VVX9 1 64203623-64267368 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "testis: 30.0" "Group enriched" "Detected in some" 10 "Early spermatids: 213.2;Late primary spermatocytes: 174.4;Late spermatids: 445.5" "Cell type enriched" "Detected in single" 26 "choroid plexus epithelial cell: 24.2" "Not detected" "Not detected" "Region enriched" "Detected in single" 4 "choroid plexus: 1.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 23: Choroid plexus - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 7 UBE2V1 "CROC-1, CROC1, UBE2V, UEV-1, UEV1A" ENSG00000244687 "Ubiquitin conjugating enzyme E2 V1" Q13404 20 50081124-50115959 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bergmann glia: 51.2;Brain excitatory neurons: 62.7;Brain inhibitory neurons: 55.3;Esophageal apical cells: 57.3;Microglia: 57.3;Oligodendrocytes: 49.9;Other brain neurons: 64.4;Platelets: 54.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "HPA052535, HPA053186" Enhanced Nucleoplasm NA NA 2000000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 98: Neurons - Neurotransmission & signaling" 37 Nucleoplasm "HPA052535: , HPA053186: " "unprognostic (4.70e-2)" "unprognostic (1.42e-3)" "unprognostic (9.22e-2)" "unprognostic (2.15e-1)" "unprognostic (3.41e-1)" "unprognostic (2.91e-1)" "unprognostic (2.08e-1)" "unprognostic (1.28e-1)" "unprognostic (9.58e-3)" "unprognostic (1.99e-2)" "unprognostic (6.06e-3)" "unprognostic (1.24e-2)" "unprognostic (1.65e-1)" "validated prognostic unfavorable (1.48e-4)" "validated prognostic unfavorable (3.63e-4)" "potential prognostic unfavorable (1.45e-4)" "unprognostic (9.88e-2)" "unprognostic (1.22e-2)" "unprognostic (1.13e-1)" "unprognostic (8.99e-2)" "unprognostic (1.73e-2)" "unprognostic (6.88e-2)" "potential prognostic unfavorable (2.94e-4)" "unprognostic (1.86e-1)" "unprognostic (4.99e-2)" "unprognostic (7.30e-2)" "unprognostic (2.04e-2)" "unprognostic (3.36e-2)" "unprognostic (1.35e-2)" "unprognostic (2.05e-2)" "unprognostic (8.94e-2)" UBE2V2 "DDVit-1, DDVIT1, EDAF-1, EDPF-1, EDPF1, MMS2, UEV-2, UEV2" ENSG00000169139 "Ubiquitin conjugating enzyme E2 V2" Q15819 8 48008415-48064708 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 401.3;Esophageal suprabasal cells: 293.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Smooth muscle cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052535, HPA053186" Supported Nucleoplasm NA NA 1500000 "Cluster 1: T-cells - Unknown function" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 14: Neurons - Synaptic function" "Cluster 40: Non-specific - Unknown function" "Cluster 85: Squamous epithelial cells - Keratinization" 12 Nucleoplasm "HPA052535: , HPA053186: " "unprognostic (8.31e-3)" "potential prognostic unfavorable (8.07e-4)" "unprognostic (1.37e-1)" "unprognostic (2.19e-2)" "unprognostic (2.11e-1)" "unprognostic (9.24e-2)" "unprognostic (6.16e-2)" "unprognostic (4.76e-2)" "unprognostic (2.18e-2)" "potential prognostic unfavorable (3.74e-7)" "potential prognostic favorable (1.64e-4)" "unprognostic (3.43e-1)" "unprognostic (7.22e-2)" "potential prognostic unfavorable (9.33e-4)" "unprognostic (5.06e-3)" "potential prognostic unfavorable (6.97e-5)" "unprognostic (2.29e-2)" "unprognostic (6.89e-2)" "unprognostic (4.19e-2)" "unprognostic (3.18e-2)" "unprognostic (3.93e-2)" "unprognostic (1.90e-2)" "potential prognostic unfavorable (2.50e-4)" "unprognostic (1.85e-1)" "unprognostic (9.12e-2)" "unprognostic (1.95e-1)" "unprognostic (1.21e-3)" "unprognostic (7.61e-2)" "unprognostic (1.36e-1)" "unprognostic (5.27e-2)" "unprognostic (8.74e-2)" UBE2W "FLJ11011, UBC-16" ENSG00000104343 "Ubiquitin conjugating enzyme E2 W" Q96B02 8 73780097-73878910 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 62.7;Bergmann glia: 93.2;Brain excitatory neurons: 129.1;Brain inhibitory neurons: 105.1;Choroid plexus epithelial cells: 150.9;Early spermatids: 58.8;Ependymal cells: 82.4;Late spermatids: 49.2;Microglia: 332.0;Oligodendrocyte progenitor cells: 94.7;Oligodendrocytes: 90.1;Other brain neurons: 104.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045161, HPA073181" Uncertain Approved Nucleoli NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 76: Non-specific - Metabolism" "Cluster 34: Non-specific - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 22: Non-specific - Basic cellular functions" 42 Nucleoli "HPA045161: , HPA073181: " "unprognostic (4.74e-2)" "unprognostic (4.13e-2)" "unprognostic (1.08e-1)" "unprognostic (4.93e-2)" "unprognostic (1.16e-1)" "unprognostic (1.41e-1)" "unprognostic (1.48e-2)" "unprognostic (3.31e-2)" "unprognostic (1.02e-1)" "unprognostic (1.95e-3)" "potential prognostic favorable (2.52e-6)" "unprognostic (1.01e-1)" "unprognostic (8.36e-2)" "unprognostic (3.35e-3)" "unprognostic (6.86e-2)" "unprognostic (1.07e-2)" "unprognostic (2.72e-2)" "unprognostic (1.37e-1)" "unprognostic (6.81e-2)" "unprognostic (2.73e-2)" "unprognostic (1.50e-3)" "unprognostic (2.12e-2)" "unprognostic (3.29e-3)" "unprognostic (2.65e-1)" "unprognostic (3.51e-2)" "unprognostic (5.38e-2)" "unprognostic (2.48e-1)" "unprognostic (2.28e-1)" "unprognostic (2.84e-1)" "unprognostic (1.32e-1)" "unprognostic (6.02e-2)" UBE2Z "FLJ13855, USE1" ENSG00000159202 "Ubiquitin conjugating enzyme E2 Z" Q9H832 17 48908407-48929056 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Liver - Vascular endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007922 Approved Supported Nucleoplasm,Cytosol NA NA 24000 "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 17: Non-specific - RNA processing" 16 "Nucleoplasm, Cytosol" "HPA007922: " "unprognostic (8.08e-2)" "unprognostic (3.97e-1)" "unprognostic (3.04e-1)" "unprognostic (3.04e-2)" "unprognostic (4.19e-2)" "potential prognostic unfavorable (3.14e-4)" "unprognostic (4.77e-2)" "unprognostic (2.73e-1)" "unprognostic (1.45e-1)" "potential prognostic unfavorable (2.76e-4)" "unprognostic (3.63e-2)" "unprognostic (2.43e-1)" "unprognostic (1.46e-1)" "validated prognostic unfavorable (3.62e-4)" "validated prognostic unfavorable (5.41e-4)" "potential prognostic unfavorable (8.17e-5)" "unprognostic (1.78e-3)" "unprognostic (1.04e-1)" "unprognostic (5.51e-2)" "unprognostic (4.53e-2)" "unprognostic (2.47e-3)" "unprognostic (8.95e-2)" "unprognostic (1.38e-3)" "unprognostic (3.63e-2)" "unprognostic (9.31e-2)" "unprognostic (4.46e-2)" "unprognostic (1.79e-1)" "unprognostic (2.31e-1)" "unprognostic (1.06e-1)" "unprognostic (7.74e-3)" "unprognostic (7.27e-2)" UBE3A "ANCR, AS, E6-AP, EPVE6AP, FLJ26981, HPVE6A" ENSG00000114062 "Ubiquitin protein ligase E3A" Q05086 15 25333728-25439051 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms, Host-virus interaction, Ubl conjugation pathway" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009723, HPA039410, HPA040380" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 2: Neurons - Nucleosome" "Cluster 58: Non-specific - Nuclear processes" "Cluster 98: Neurons - Neurotransmission & signaling" 134 Nucleoplasm Cytosol "CAB009723: , HPA039410: , HPA040380: " "unprognostic (7.13e-2)" "unprognostic (3.52e-2)" "unprognostic (4.62e-2)" "unprognostic (4.25e-1)" "unprognostic (1.14e-1)" "unprognostic (4.28e-2)" "unprognostic (7.49e-2)" "unprognostic (3.68e-2)" "unprognostic (1.59e-1)" "potential prognostic unfavorable (6.88e-4)" "potential prognostic favorable (3.65e-5)" "unprognostic (1.31e-3)" "unprognostic (3.47e-1)" "unprognostic (2.26e-1)" "unprognostic (2.00e-1)" "unprognostic (1.16e-1)" "unprognostic (8.18e-2)" "unprognostic (2.06e-1)" "unprognostic (4.97e-3)" "unprognostic (8.67e-2)" "unprognostic (6.87e-3)" "unprognostic (4.25e-3)" "unprognostic (2.13e-2)" "unprognostic (6.25e-2)" "unprognostic (2.64e-2)" "unprognostic (1.95e-1)" "unprognostic (1.52e-1)" "unprognostic (6.03e-2)" "unprognostic (3.68e-2)" "unprognostic (1.68e-1)" "unprognostic (3.58e-1)" UBE3B ENSG00000151148 "Ubiquitin protein ligase E3B" Q7Z3V4 12 109477402-109536705 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041012 Approved Approved "Nuclear speckles,Mitochondria" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 34: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 32 "Nuclear speckles" Mitochondria "HPA041012: " "unprognostic (3.04e-1)" "unprognostic (1.74e-3)" "unprognostic (2.73e-1)" "unprognostic (4.19e-2)" "unprognostic (1.68e-1)" "unprognostic (2.41e-1)" "unprognostic (1.74e-1)" "unprognostic (1.16e-1)" "unprognostic (3.49e-1)" "unprognostic (1.81e-2)" "potential prognostic favorable (1.12e-5)" "unprognostic (1.31e-1)" "unprognostic (1.28e-2)" "unprognostic (5.39e-3)" "unprognostic (8.01e-2)" "unprognostic (1.11e-1)" "unprognostic (6.34e-2)" "unprognostic (7.15e-2)" "unprognostic (3.97e-1)" "unprognostic (1.96e-2)" "unprognostic (3.74e-2)" "unprognostic (1.95e-1)" "unprognostic (1.30e-3)" "unprognostic (6.41e-2)" "unprognostic (1.42e-2)" "unprognostic (4.14e-2)" "unprognostic (1.11e-1)" "unprognostic (2.15e-1)" "unprognostic (4.77e-2)" "unprognostic (1.18e-1)" "unprognostic (2.70e-2)" UBE3C "KIAA0010, KIAA10" ENSG00000009335 "Ubiquitin protein ligase E3C" Q15386 7 157138916-157269370 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039915, HPA076403" Approved Approved "Vesicles,Lipid droplets,Cytosol" NA NA 3300 "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 39: Non-specific - Transcription" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 71 Cytosol "Vesicles, Lipid droplets" "HPA039915: , HPA076403: " "unprognostic (4.23e-2)" "unprognostic (2.16e-2)" "unprognostic (5.77e-3)" "unprognostic (3.49e-3)" "unprognostic (2.34e-1)" "unprognostic (8.13e-3)" "unprognostic (1.20e-1)" "unprognostic (2.93e-1)" "unprognostic (6.95e-2)" "unprognostic (2.68e-2)" "potential prognostic favorable (1.10e-5)" "unprognostic (1.28e-2)" "unprognostic (4.31e-1)" "unprognostic (7.12e-2)" "unprognostic (5.52e-3)" "unprognostic (2.13e-2)" "potential prognostic unfavorable (1.89e-5)" "unprognostic (2.58e-1)" "unprognostic (4.72e-3)" "unprognostic (1.48e-1)" "unprognostic (2.55e-1)" "unprognostic (4.50e-3)" "unprognostic (1.44e-1)" "unprognostic (1.42e-1)" "unprognostic (1.27e-1)" "unprognostic (1.33e-1)" "unprognostic (9.29e-2)" "unprognostic (1.52e-1)" "unprognostic (4.86e-1)" "unprognostic (1.25e-1)" "unprognostic (3.92e-1)" UBE3D "C6orf157, DKFZp434A1520, H10BH, UBE2CBP, YJR141W" ENSG00000118420 "Ubiquitin protein ligase E3D" Q7Z6J8 6 82892390-83065841 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ependymal cells: 603.1;Respiratory ciliated cells: 240.0" "Cell type enriched" "Detected in all" 4 "ependymal cell: 743.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027231 Approved Approved "Rods & Rings" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 65: Brain - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 34: Ciliated cells - Cilia assembly & function" 10 "Rods & Rings" "HPA027231: " "unprognostic (4.45e-2)" "unprognostic (1.92e-1)" "unprognostic (3.81e-2)" "unprognostic (1.12e-1)" "potential prognostic favorable (4.91e-4)" "unprognostic (1.54e-3)" "unprognostic (3.48e-3)" "unprognostic (1.21e-1)" "validated prognostic favorable (4.85e-10)" "validated prognostic favorable (1.66e-4)" "unprognostic (2.65e-1)" "potential prognostic unfavorable (2.00e-5)" "unprognostic (2.23e-1)" "unprognostic (2.74e-1)" "unprognostic (1.84e-1)" "unprognostic (6.41e-2)" "unprognostic (1.81e-2)" "unprognostic (4.24e-3)" "unprognostic (6.51e-3)" "unprognostic (5.50e-2)" "unprognostic (1.58e-1)" "potential prognostic favorable (2.23e-5)" "unprognostic (2.16e-1)" "unprognostic (2.87e-1)" "unprognostic (1.83e-1)" "unprognostic (2.20e-1)" "unprognostic (1.71e-2)" "unprognostic (1.13e-1)" UBE4A "E4, KIAA0126, UBOX2, UFD2" ENSG00000110344 "Ubiquitination factor E4A" Q14139 11 118359600-118399211 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055035, HPA064010" Approved Approved "Nuclear speckles" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 61: Non-specific - Transcription" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 9: T-cells - Adaptive immunity: Regulation" 23 "Nuclear speckles" "HPA055035: , HPA064010: " "unprognostic (5.90e-3)" "unprognostic (2.26e-3)" "unprognostic (3.40e-2)" "unprognostic (2.52e-2)" "unprognostic (1.47e-1)" "unprognostic (8.82e-2)" "unprognostic (5.05e-2)" "unprognostic (3.83e-3)" "unprognostic (3.47e-1)" "unprognostic (6.23e-3)" "potential prognostic favorable (3.45e-5)" "unprognostic (3.89e-3)" "unprognostic (6.76e-3)" "unprognostic (1.06e-2)" "unprognostic (1.55e-1)" "unprognostic (1.32e-1)" "unprognostic (6.18e-3)" "unprognostic (2.35e-1)" "unprognostic (1.20e-1)" "unprognostic (6.17e-2)" "potential prognostic unfavorable (1.22e-4)" "unprognostic (9.73e-3)" "unprognostic (2.60e-1)" "unprognostic (1.39e-1)" "unprognostic (1.09e-3)" "unprognostic (9.48e-3)" "unprognostic (3.26e-2)" "unprognostic (1.42e-1)" "unprognostic (2.92e-1)" "unprognostic (1.09e-1)" "unprognostic (7.90e-2)" UBE4B "E4, KIAA0684, UBOX3, UFD2" ENSG00000130939 "Ubiquitination factor E4B" O95155 1 10032832-10181239 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019219 Approved NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 22 "HPA019219: " "unprognostic (1.52e-1)" "unprognostic (4.05e-2)" "unprognostic (4.43e-2)" "unprognostic (5.15e-2)" "unprognostic (4.52e-2)" "unprognostic (2.60e-1)" "unprognostic (8.51e-2)" "unprognostic (1.88e-2)" "unprognostic (4.12e-2)" "potential prognostic unfavorable (7.46e-5)" "potential prognostic favorable (6.42e-7)" "unprognostic (5.85e-3)" "unprognostic (3.90e-1)" "potential prognostic unfavorable (2.08e-5)" "unprognostic (1.02e-2)" "unprognostic (2.41e-1)" "unprognostic (2.82e-1)" "unprognostic (5.45e-2)" "unprognostic (1.00e-1)" "unprognostic (4.74e-2)" "unprognostic (5.05e-2)" "unprognostic (6.84e-2)" "unprognostic (1.48e-1)" "unprognostic (4.39e-1)" "unprognostic (8.72e-2)" "unprognostic (1.62e-2)" "unprognostic (6.12e-2)" "unprognostic (2.39e-1)" "unprognostic (4.04e-1)" "unprognostic (6.62e-2)" "unprognostic (5.52e-2)" UBFD1 "FLJ38870, FLJ42145, UBPH" ENSG00000103353 "Ubiquitin family domain containing 1" O14562 16 23557721-23574389 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 74.7" "Cell type enhanced" "Detected in many" "Early spermatids: 74.2;Late spermatids: 110.8;Myonuclei: 69.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051746 Approved Nucleoplasm,Nucleoli,Midbody Yes NA "Cluster 30: Non-specific - DNA binding" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 1: Neurons - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 2 Nucleoplasm "Nucleoli, Midbody" "HPA051746: " "unprognostic (1.42e-1)" "unprognostic (2.84e-2)" "unprognostic (4.07e-2)" "unprognostic (1.93e-1)" "unprognostic (1.25e-1)" "unprognostic (2.29e-1)" "unprognostic (7.10e-2)" "unprognostic (2.47e-2)" "unprognostic (2.17e-1)" "unprognostic (1.12e-1)" "unprognostic (3.69e-3)" "unprognostic (1.01e-1)" "unprognostic (4.80e-3)" "unprognostic (2.55e-3)" "unprognostic (4.91e-2)" "unprognostic (2.09e-2)" "unprognostic (2.03e-2)" "unprognostic (1.60e-1)" "unprognostic (3.18e-1)" "unprognostic (2.17e-1)" "unprognostic (7.04e-2)" "unprognostic (4.13e-2)" "unprognostic (1.39e-3)" "unprognostic (2.57e-2)" "unprognostic (7.51e-3)" "unprognostic (1.43e-1)" "unprognostic (3.36e-1)" "unprognostic (6.24e-2)" "unprognostic (1.53e-1)" "unprognostic (1.82e-1)" "unprognostic (1.14e-1)" UBIAD1 "SCCD, TERE1" ENSG00000120942 "UbiA prenyltransferase domain containing 1" Q9Y5Z9 1 11273198-11296049 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Menaquinone biosynthesis, Ubiquinone biosynthesis" "Prenyltransferase, Transferase" "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Sebaceous gland cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044862 Approved Vesicles NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 45 Vesicles "HPA044862: " "unprognostic (1.20e-2)" "unprognostic (1.81e-1)" "unprognostic (1.89e-1)" "unprognostic (2.76e-2)" "unprognostic (6.02e-2)" "unprognostic (4.51e-2)" "unprognostic (8.78e-3)" "unprognostic (1.03e-2)" "unprognostic (7.40e-2)" "unprognostic (4.65e-2)" "potential prognostic favorable (8.86e-6)" "unprognostic (3.77e-3)" "unprognostic (1.21e-1)" "validated prognostic unfavorable (7.81e-4)" "validated prognostic unfavorable (3.22e-7)" "unprognostic (2.45e-1)" "unprognostic (5.13e-2)" "unprognostic (1.21e-1)" "unprognostic (2.71e-2)" "unprognostic (6.83e-2)" "unprognostic (3.07e-1)" "unprognostic (1.51e-1)" "unprognostic (3.40e-1)" "unprognostic (4.75e-1)" "unprognostic (2.08e-2)" "unprognostic (2.61e-1)" "unprognostic (1.89e-1)" "unprognostic (1.45e-1)" "unprognostic (4.99e-1)" "unprognostic (7.12e-3)" "unprognostic (5.53e-2)" UBL3 "DKFZP434K151, FLJ32018, HCG-1, PNSC1" ENSG00000122042 "Ubiquitin like 3" O95164 13 29764371-29850617 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1450.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 1, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053772, HPA058781" Uncertain Approved Centrosome NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 84: Apical squamous epithelium - Cornification" 6 Centrosome "HPA053772: , HPA058781: " "unprognostic (7.41e-3)" "unprognostic (1.39e-2)" "unprognostic (1.77e-1)" "unprognostic (2.05e-1)" "unprognostic (3.58e-1)" "unprognostic (1.78e-1)" "unprognostic (8.29e-2)" "unprognostic (4.83e-2)" "unprognostic (1.36e-1)" "unprognostic (3.56e-2)" "potential prognostic favorable (1.91e-5)" "unprognostic (1.78e-3)" "unprognostic (1.89e-2)" "unprognostic (2.67e-1)" "unprognostic (1.59e-1)" "unprognostic (5.57e-2)" "unprognostic (4.20e-1)" "unprognostic (4.54e-2)" "unprognostic (2.15e-1)" "unprognostic (1.25e-2)" "unprognostic (1.70e-3)" "unprognostic (5.00e-2)" "unprognostic (1.71e-1)" "unprognostic (1.18e-1)" "unprognostic (1.13e-1)" "unprognostic (1.75e-1)" "unprognostic (5.17e-1)" "unprognostic (3.80e-3)" "unprognostic (1.73e-1)" "unprognostic (2.27e-1)" "unprognostic (7.63e-2)" UBL4A "DXS254E, GDX, GET5, MDY2, TMA24, UBL4" ENSG00000102178 "Ubiquitin like 4A" P11441 X 154483717-154486615 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Megakaryocytes: 210.2;Platelets: 435.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003617 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 36: Non-specific - mRNA processing" "Cluster 47: Platelets - Hemostasis" 53 "Nucleoplasm, Cytosol" "HPA003617: " "unprognostic (3.73e-2)" "potential prognostic unfavorable (7.12e-4)" "unprognostic (4.39e-1)" "unprognostic (1.48e-1)" "unprognostic (1.70e-2)" "unprognostic (3.61e-2)" "unprognostic (1.07e-1)" "unprognostic (2.68e-1)" "unprognostic (1.15e-1)" "unprognostic (1.56e-2)" "unprognostic (1.81e-2)" "unprognostic (5.68e-2)" "unprognostic (2.33e-2)" "potential prognostic unfavorable (4.50e-4)" "unprognostic (1.15e-2)" "unprognostic (2.23e-2)" "unprognostic (1.26e-2)" "unprognostic (1.98e-1)" "unprognostic (2.86e-1)" "unprognostic (1.17e-2)" "unprognostic (3.03e-3)" "unprognostic (2.24e-2)" "unprognostic (2.08e-1)" "unprognostic (1.77e-1)" "unprognostic (2.98e-2)" "unprognostic (5.05e-1)" "unprognostic (4.65e-2)" "unprognostic (9.10e-2)" "unprognostic (2.05e-2)" "unprognostic (5.34e-1)" "unprognostic (2.21e-1)" UBL4B FLJ25690 ENSG00000186150 "Ubiquitin like 4B" Q8N7F7 1 110112443-110113947 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 33 "testis: 104.2" "Cell type enriched" "Detected in some" 7 "Late spermatids: 11618.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pituitary gland - Fibroblasts, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA031364 Enhanced NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 38: Sub-cortical - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 7 "HPA031364: " "unprognostic (2.15e-2)" "unprognostic (4.35e-3)" UBL5 ENSG00000198258 "Ubiquitin like 5" Q9BZL1 19 9827892-9830115 "Essential proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 2232.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 23: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 39 "unprognostic (2.85e-2)" "unprognostic (1.80e-2)" "unprognostic (9.01e-3)" "potential prognostic favorable (1.83e-4)" "unprognostic (1.15e-1)" "unprognostic (3.81e-2)" "unprognostic (2.08e-1)" "unprognostic (1.09e-1)" "unprognostic (2.02e-1)" "unprognostic (1.62e-2)" "unprognostic (3.74e-3)" "unprognostic (9.27e-3)" "unprognostic (1.99e-1)" "unprognostic (7.37e-3)" "unprognostic (2.63e-3)" "unprognostic (1.04e-1)" "unprognostic (1.77e-1)" "unprognostic (2.70e-2)" "unprognostic (4.77e-2)" "unprognostic (6.13e-3)" "unprognostic (3.65e-1)" "unprognostic (8.71e-2)" "unprognostic (9.54e-2)" "unprognostic (6.32e-2)" "unprognostic (1.15e-1)" "unprognostic (1.25e-1)" "unprognostic (5.23e-2)" "unprognostic (1.38e-1)" "unprognostic (5.18e-2)" "unprognostic (3.60e-2)" "unprognostic (2.27e-1)" UBL7 "BMSC-UbP, MGC14421" ENSG00000138629 "Ubiquitin like 7" Q96S82 15 74445977-74461182 "Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 48.0;Early spermatids: 56.3;Extravillous trophoblasts: 50.1;Late primary spermatocytes: 80.9;Late spermatids: 248.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Skin - Keratinocyte (granular), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040423, HPA041897" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 15 Nucleoplasm Cytosol "HPA040423: , HPA041897: " "unprognostic (1.82e-1)" "unprognostic (6.24e-2)" "unprognostic (5.10e-2)" "potential prognostic favorable (8.69e-6)" "unprognostic (2.00e-2)" "unprognostic (2.09e-1)" "unprognostic (4.89e-2)" "unprognostic (4.49e-3)" "unprognostic (1.71e-1)" "unprognostic (5.32e-3)" "unprognostic (4.55e-2)" "unprognostic (6.38e-2)" "potential prognostic favorable (5.95e-4)" "unprognostic (1.22e-2)" "unprognostic (1.01e-3)" "unprognostic (1.05e-1)" "unprognostic (3.20e-1)" "unprognostic (1.92e-2)" "unprognostic (1.67e-1)" "unprognostic (1.77e-1)" "unprognostic (1.32e-1)" "unprognostic (2.04e-2)" "unprognostic (1.63e-2)" "unprognostic (4.48e-2)" "unprognostic (5.40e-2)" "unprognostic (5.20e-2)" "unprognostic (3.22e-1)" "unprognostic (3.42e-3)" "unprognostic (1.07e-1)" "unprognostic (7.69e-2)" "unprognostic (4.19e-3)" UBLCP1 "CPUB1, MGC10067" ENSG00000164332 "Ubiquitin like domain containing CTD phosphatase 1" Q8WVY7 5 159263290-159286036 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 149.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039615 Approved Supported "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA 5300 "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 36 "Nucleoplasm, Nucleoli, Nucleoli rim" "HPA039615: " "unprognostic (1.33e-1)" "unprognostic (9.18e-2)" "unprognostic (8.09e-2)" "unprognostic (1.49e-1)" "unprognostic (7.46e-2)" "unprognostic (2.64e-1)" "unprognostic (9.99e-2)" "potential prognostic unfavorable (1.97e-4)" "unprognostic (7.92e-2)" "unprognostic (4.73e-2)" "potential prognostic favorable (1.16e-6)" "unprognostic (1.05e-1)" "unprognostic (9.31e-2)" "unprognostic (3.25e-2)" "unprognostic (6.40e-2)" "unprognostic (7.88e-3)" "unprognostic (1.58e-1)" "unprognostic (5.12e-2)" "unprognostic (2.63e-1)" "unprognostic (3.74e-2)" "unprognostic (8.75e-3)" "unprognostic (9.80e-3)" "unprognostic (1.24e-2)" "unprognostic (7.03e-2)" "unprognostic (8.16e-3)" "unprognostic (7.02e-2)" "unprognostic (6.58e-2)" "unprognostic (4.48e-2)" "unprognostic (1.50e-1)" "unprognostic (2.67e-3)" "unprognostic (2.68e-1)" UBN1 ENSG00000118900 "Ubinuclein 1" Q9NPG3 16 4846665-4882401 "Predicted intracellular proteins" "Host-virus interaction" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 487.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 8 "neutrophil: 14.2" "Lineage enriched" "Detected in all" 8 "granulocytes: 14.2" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA061029, HPA069036, HPA069045" Supported Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 15: Non-specific - Transcription" "Cluster 54: Non-specific - Transcription" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 14 Nucleoplasm "Nuclear bodies" "HPA061029: , HPA069036: , HPA069045: " "unprognostic (5.53e-2)" "unprognostic (1.50e-2)" "unprognostic (1.18e-1)" "unprognostic (4.12e-2)" "unprognostic (5.23e-2)" "unprognostic (2.39e-1)" "unprognostic (1.62e-1)" "unprognostic (1.93e-1)" "unprognostic (1.36e-1)" "unprognostic (1.29e-2)" "validated prognostic favorable (4.31e-4)" "validated prognostic favorable (8.63e-4)" "unprognostic (6.62e-2)" "unprognostic (8.83e-3)" "unprognostic (1.89e-2)" "unprognostic (2.51e-2)" "unprognostic (1.34e-2)" "unprognostic (1.45e-2)" "unprognostic (3.34e-2)" "unprognostic (6.56e-3)" "unprognostic (5.57e-3)" "unprognostic (1.52e-3)" "unprognostic (4.22e-3)" "unprognostic (9.30e-2)" "unprognostic (1.56e-2)" "unprognostic (1.33e-1)" "unprognostic (1.64e-1)" "unprognostic (3.19e-1)" "unprognostic (3.86e-1)" "unprognostic (5.90e-3)" "unprognostic (7.99e-2)" UBN2 "FLJ25778, KIAA2030" ENSG00000157741 "Ubinuclein 2" Q6ZU65 7 139230356-139308236 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 276.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "basophil: 8.4" "Lineage enriched" "Detected in many" 4 "granulocytes: 8.4" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019743, HPA020122, HPA020124" Uncertain Enhanced Nucleoplasm NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 47: Testis - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 39: Non-specific - Transcription" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 18 Nucleoplasm "HPA019743: , HPA020122: , HPA020124: " "unprognostic (1.58e-2)" "unprognostic (4.83e-1)" "unprognostic (7.46e-2)" "unprognostic (4.30e-2)" "unprognostic (8.55e-3)" "unprognostic (5.63e-2)" "unprognostic (1.83e-1)" "unprognostic (6.26e-3)" "potential prognostic favorable (4.96e-4)" "unprognostic (2.59e-2)" "unprognostic (1.67e-1)" "potential prognostic favorable (2.78e-4)" "unprognostic (2.79e-2)" "unprognostic (1.86e-3)" "unprognostic (2.45e-1)" "unprognostic (8.63e-2)" "unprognostic (6.48e-2)" "unprognostic (3.01e-1)" "unprognostic (5.50e-2)" "unprognostic (1.44e-1)" "unprognostic (3.74e-1)" "unprognostic (3.81e-1)" "unprognostic (7.94e-3)" "unprognostic (2.43e-2)" "unprognostic (3.84e-2)" "unprognostic (1.32e-1)" "unprognostic (2.27e-3)" "unprognostic (1.04e-1)" "unprognostic (5.01e-1)" "unprognostic (9.72e-3)" "unprognostic (1.58e-1)" UBOX5 "KIAA0860, RNF37, Ubce7ip5, UIP5" ENSG00000185019 "U-box domain containing 5" O94941 20 3107573-3160196 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 49.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028871 Approved Approved Nucleoplasm NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 24: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 7: Non-specific - Transcription" 11 Nucleoplasm "HPA028871: " "unprognostic (2.37e-2)" "unprognostic (2.20e-2)" "unprognostic (2.85e-1)" "unprognostic (4.30e-2)" "unprognostic (1.23e-1)" "unprognostic (1.02e-1)" "unprognostic (8.64e-2)" "unprognostic (6.96e-2)" "unprognostic (1.23e-2)" "unprognostic (3.44e-2)" "unprognostic (4.44e-3)" "unprognostic (5.36e-2)" "unprognostic (8.66e-2)" "unprognostic (1.09e-1)" "potential prognostic unfavorable (1.56e-4)" "unprognostic (1.61e-1)" "unprognostic (3.11e-1)" "unprognostic (3.15e-2)" "unprognostic (3.52e-1)" "unprognostic (1.40e-2)" "unprognostic (1.29e-1)" "potential prognostic favorable (5.72e-4)" "unprognostic (1.07e-1)" "unprognostic (1.64e-1)" "unprognostic (1.51e-1)" "unprognostic (6.36e-3)" "unprognostic (1.21e-1)" "unprognostic (1.10e-1)" "unprognostic (1.68e-1)" "unprognostic (8.03e-3)" "unprognostic (8.53e-3)" UBP1 LBP-1a ENSG00000153560 "Upstream binding protein 1" Q9NZI7 3 33388336-33441371 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epicardial cells: 179.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003967 Supported Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 17: Non-specific - RNA processing" 5 Nucleoplasm "HPA003967: " "unprognostic (8.06e-3)" "unprognostic (1.00e-1)" "unprognostic (2.08e-1)" "unprognostic (3.39e-1)" "unprognostic (1.09e-1)" "unprognostic (1.31e-1)" "unprognostic (1.26e-1)" "unprognostic (4.93e-2)" "unprognostic (4.98e-2)" "unprognostic (2.66e-2)" "unprognostic (4.47e-3)" "unprognostic (1.03e-1)" "unprognostic (2.77e-1)" "unprognostic (3.92e-3)" "unprognostic (2.58e-1)" "unprognostic (1.34e-2)" "unprognostic (8.23e-2)" "unprognostic (1.62e-1)" "unprognostic (9.33e-3)" "unprognostic (2.58e-1)" "unprognostic (1.40e-1)" "unprognostic (6.44e-2)" "unprognostic (1.68e-2)" "unprognostic (3.73e-3)" "potential prognostic favorable (2.66e-4)" "unprognostic (1.11e-1)" "unprognostic (8.04e-2)" "unprognostic (1.30e-1)" "unprognostic (4.19e-1)" "unprognostic (1.15e-1)" "unprognostic (2.42e-1)" UBQLN1 "DA41, DSK2, PLIC-1, XDRP1" ENSG00000135018 "Ubiquilin 1" Q9UMX0 9 83659968-83707958 "Plasma proteins, Predicted intracellular proteins" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037256, HPA054143" Supported Supported Nucleoplasm,Cytosol NA NA 950000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 311 Nucleoplasm Cytosol "CAB037256: , HPA054143: " "unprognostic (2.07e-1)" "unprognostic (2.15e-2)" "unprognostic (6.56e-2)" "unprognostic (4.44e-3)" "unprognostic (1.46e-1)" "potential prognostic unfavorable (5.96e-4)" "unprognostic (1.56e-1)" "unprognostic (8.37e-2)" "unprognostic (9.88e-2)" "unprognostic (2.15e-2)" "potential prognostic favorable (4.63e-6)" "unprognostic (4.68e-3)" "unprognostic (1.57e-1)" "unprognostic (2.70e-2)" "unprognostic (1.80e-1)" "unprognostic (6.99e-3)" "unprognostic (2.95e-1)" "unprognostic (5.27e-2)" "unprognostic (3.79e-1)" "unprognostic (7.21e-2)" "unprognostic (7.17e-3)" "unprognostic (5.02e-2)" "unprognostic (2.36e-1)" "unprognostic (8.24e-2)" "unprognostic (1.17e-1)" "unprognostic (2.55e-1)" "unprognostic (2.69e-1)" "unprognostic (3.91e-2)" "unprognostic (1.48e-1)" "unprognostic (1.63e-2)" "unprognostic (1.03e-1)" UBQLN2 "Chap1, CHAP1/DSK2, Dsk2, LIC-2, N4BP4, PLIC-2, PLIC2, RIHFB2157" ENSG00000188021 "Ubiquilin 2" Q9UHD9 X 56563627-56567868 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Autophagy "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006431, CAB013481" Enhanced Supported "Plasma membrane,Cytosol" NA NA 910000 "Cluster 35: Neutrophils - Protein binding" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 14: Neurons - Synaptic function" "Cluster 36: Non-specific - mRNA processing" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 344 Cytosol "Plasma membrane" "CAB013481: , HPA006431: " "unprognostic (4.72e-2)" "potential prognostic unfavorable (9.10e-4)" "unprognostic (3.54e-1)" "unprognostic (1.02e-1)" "unprognostic (2.66e-1)" "unprognostic (1.04e-1)" "unprognostic (2.28e-2)" "unprognostic (1.40e-1)" "unprognostic (8.74e-2)" "unprognostic (8.32e-2)" "potential prognostic favorable (2.19e-4)" "unprognostic (3.70e-2)" "unprognostic (4.68e-2)" "unprognostic (7.26e-3)" "unprognostic (2.25e-2)" "unprognostic (1.95e-2)" "unprognostic (2.31e-2)" "unprognostic (1.81e-1)" "unprognostic (2.10e-1)" "unprognostic (1.72e-1)" "unprognostic (4.65e-2)" "unprognostic (3.78e-2)" "unprognostic (7.34e-3)" "unprognostic (1.23e-1)" "unprognostic (6.75e-2)" "unprognostic (1.90e-1)" "unprognostic (8.39e-2)" "unprognostic (6.71e-2)" "unprognostic (1.42e-1)" "unprognostic (7.63e-2)" "unprognostic (5.90e-2)" UBQLN3 TUP-1 ENSG00000175520 "Ubiquilin 3" Q9H347 11 5507300-5509958 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 624 "testis: 151.3" "Group enriched" "Detected in some" 6 "Early spermatids: 16.7;Late spermatids: 47.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA020547, HPA062018" Enhanced NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 44: Non-specific - Mixed function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 6 "HPA020547: , HPA062018: " UBQLN4 "A1U, C1orf6, UBIN" ENSG00000160803 "Ubiquilin 4" Q9NRR5 1 156035299-156053798 "Disease related genes, Essential proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Autophagy, DNA damage, DNA repair" "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 9.6" "Lineage enriched" "Detected in many" 5 "granulocytes: 9.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061797 Approved Supported Nucleoplasm NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 45: Non-specific - Nuclear processes" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 70 Nucleoplasm "HPA061797: " "unprognostic (2.22e-2)" "unprognostic (1.38e-2)" "unprognostic (3.38e-1)" "unprognostic (1.96e-1)" "unprognostic (5.44e-2)" "unprognostic (8.31e-2)" "unprognostic (1.51e-2)" "potential prognostic favorable (1.57e-4)" "unprognostic (8.48e-2)" "unprognostic (3.77e-2)" "unprognostic (2.47e-1)" "unprognostic (1.71e-1)" "potential prognostic unfavorable (2.00e-4)" "unprognostic (1.34e-3)" "unprognostic (1.86e-2)" "unprognostic (1.99e-3)" "unprognostic (7.36e-2)" "unprognostic (9.46e-2)" "unprognostic (4.42e-2)" "unprognostic (7.61e-2)" "unprognostic (3.05e-2)" "unprognostic (1.11e-2)" "unprognostic (2.12e-1)" "unprognostic (1.00e-1)" "unprognostic (4.75e-2)" "unprognostic (1.61e-1)" "unprognostic (2.96e-1)" "unprognostic (4.74e-2)" "unprognostic (1.07e-1)" "unprognostic (2.18e-1)" "unprognostic (6.44e-2)" UBQLNL "MGC20470, MGC26958" ENSG00000175518 "Ubiquilin like" Q8IYU4 11 5514393-5518431 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "testis: 30.2" "Group enriched" "Detected in some" 13 "Early spermatids: 1.8;Late spermatids: 6.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Enteric glia cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 44: Non-specific - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 8 "unprognostic (2.14e-2)" "unprognostic (2.20e-3)" UBR1 ENSG00000159459 "Ubiquitin protein ligase E3 component n-recognin 1" Q8IWV7 15 42942897-43106113 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Endothelial cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038838, HPA038839, HPA046727" Supported Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 58: Non-specific - Nuclear processes" "Cluster 103: Non-specific - Basic cellular processes" 26 Vesicles "Nucleoplasm, Cytosol" "HPA038838: , HPA038839: , HPA046727: " "unprognostic (9.99e-2)" "unprognostic (6.96e-3)" "unprognostic (5.03e-2)" "unprognostic (1.36e-2)" "unprognostic (2.05e-1)" "unprognostic (3.55e-1)" "unprognostic (1.72e-2)" "potential prognostic favorable (8.35e-4)" "unprognostic (1.24e-1)" "unprognostic (5.18e-3)" "unprognostic (1.65e-3)" "potential prognostic favorable (1.32e-4)" "unprognostic (9.76e-2)" "unprognostic (2.39e-1)" "unprognostic (3.75e-1)" "unprognostic (1.61e-2)" "unprognostic (1.77e-1)" "unprognostic (4.47e-2)" "unprognostic (9.49e-2)" "unprognostic (1.66e-1)" "unprognostic (4.56e-3)" "unprognostic (1.21e-2)" "unprognostic (1.52e-3)" "unprognostic (1.01e-1)" "unprognostic (4.75e-2)" "unprognostic (1.08e-1)" "unprognostic (3.27e-1)" "unprognostic (8.81e-2)" "unprognostic (5.96e-2)" "unprognostic (5.32e-2)" "unprognostic (1.79e-1)" UBR2 "bA49A4.1, C6orf133, dJ392M17.3, KIAA0349" ENSG00000024048 "Ubiquitin protein ligase E3 component n-recognin 2" Q8IWV8 6 42564029-42693505 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 970.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 36.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027869, HPA027880" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 24: Neutrophils - Innate immunity signal integration" 10 Nucleoplasm "Plasma membrane" "HPA027869: , HPA027880: " "unprognostic (2.26e-3)" "unprognostic (9.27e-2)" "unprognostic (4.56e-1)" "unprognostic (1.19e-1)" "unprognostic (1.92e-1)" "unprognostic (6.04e-2)" "unprognostic (2.26e-2)" "unprognostic (4.89e-2)" "unprognostic (4.26e-2)" "unprognostic (3.66e-3)" "validated prognostic favorable (5.01e-6)" "validated prognostic favorable (2.35e-4)" "unprognostic (3.24e-2)" "unprognostic (1.13e-1)" "unprognostic (4.57e-2)" "unprognostic (1.38e-2)" "unprognostic (1.19e-1)" "unprognostic (2.24e-1)" "unprognostic (3.05e-1)" "unprognostic (2.74e-1)" "unprognostic (3.37e-1)" "unprognostic (1.80e-1)" "unprognostic (7.00e-2)" "unprognostic (1.23e-1)" "unprognostic (2.62e-3)" "unprognostic (1.98e-1)" "unprognostic (2.24e-1)" "unprognostic (2.94e-1)" "unprognostic (2.20e-1)" "unprognostic (1.39e-1)" "unprognostic (3.66e-1)" UBR3 "DKFZp434P117, FLJ37422, KIAA2024, ZNF650" ENSG00000144357 "Ubiquitin protein ligase E3 component n-recognin 3" Q6ZT12 2 169827454-170084131 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 68.6;tongue: 81.3" "Cell type enhanced" "Detected in all" "Myonuclei: 866.2;Sertoli cells: 853.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035390 Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 7: Non-specific - Transcription" 3 "Nucleoplasm, Nucleoli" "HPA035390: " "unprognostic (1.65e-1)" "unprognostic (3.86e-3)" "unprognostic (3.28e-2)" "unprognostic (8.03e-2)" "unprognostic (1.38e-2)" "unprognostic (6.36e-2)" "unprognostic (2.60e-1)" "unprognostic (5.73e-3)" "unprognostic (2.12e-1)" "unprognostic (3.08e-3)" "potential prognostic favorable (7.19e-7)" "unprognostic (1.88e-3)" "unprognostic (9.37e-2)" "unprognostic (1.68e-1)" "unprognostic (2.04e-1)" "unprognostic (1.29e-1)" "unprognostic (3.40e-1)" "unprognostic (9.21e-2)" "unprognostic (1.40e-2)" "unprognostic (2.12e-3)" "unprognostic (6.51e-3)" "unprognostic (2.10e-2)" "unprognostic (5.79e-3)" "unprognostic (2.76e-1)" "unprognostic (7.56e-2)" "unprognostic (5.53e-2)" "unprognostic (4.46e-1)" "unprognostic (5.32e-2)" "unprognostic (2.34e-1)" "unprognostic (6.01e-2)" "unprognostic (2.07e-1)" UBR4 "KIAA0462, KIAA1307, p600, RBAF600, ZUBR1" ENSG00000127481 "Ubiquitin protein ligase E3 component n-recognin 4" Q5T4S7 1 19074510-19210266 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction, Ubl conjugation pathway" "Calmodulin-binding, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 514.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 39.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013394, HPA021046" Approved Supported "Nucleoplasm,Centrosome,Cytosol,Acrosome,Perinuclear theca,Flagellar centriole,Principal piece" NA NA 26000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 24: Non-specific - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 31 Nucleoplasm "Centrosome, Cytosol, Acrosome, Perinuclear theca, Flagellar centriole, Principal piece" "HPA013394: , HPA021046: " "unprognostic (2.60e-2)" "unprognostic (2.30e-1)" "unprognostic (1.71e-1)" "unprognostic (1.04e-1)" "unprognostic (1.93e-1)" "unprognostic (1.49e-1)" "unprognostic (1.29e-1)" "unprognostic (2.40e-2)" "unprognostic (1.44e-1)" "unprognostic (7.62e-2)" "unprognostic (1.61e-1)" "unprognostic (1.36e-1)" "unprognostic (2.71e-2)" "potential prognostic unfavorable (1.45e-5)" "unprognostic (2.36e-1)" "unprognostic (1.53e-1)" "unprognostic (9.48e-2)" "unprognostic (6.62e-2)" "unprognostic (1.73e-1)" "unprognostic (2.27e-2)" "unprognostic (7.52e-3)" "unprognostic (9.15e-2)" "unprognostic (7.36e-2)" "unprognostic (2.82e-1)" "unprognostic (1.78e-1)" "potential prognostic favorable (2.48e-7)" "unprognostic (5.58e-2)" "unprognostic (2.98e-1)" "unprognostic (4.28e-1)" "unprognostic (1.36e-1)" "unprognostic (7.81e-2)" UBR5 "DD5, EDD, EDD1, HYD, KIAA0896" ENSG00000104517 "Ubiquitin protein ligase E3 component n-recognin 5" O95071 8 102252273-102412759 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053688 Supported Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 39: Testis - Nuclear processes" "Cluster 16: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 103: Non-specific - Basic cellular processes" 112 Nucleoplasm Cytosol "HPA053688: " "unprognostic (3.93e-1)" "unprognostic (3.14e-2)" "unprognostic (3.85e-1)" "unprognostic (1.15e-2)" "unprognostic (2.65e-1)" "unprognostic (4.54e-2)" "unprognostic (4.98e-2)" "unprognostic (1.34e-2)" "unprognostic (2.39e-1)" "potential prognostic unfavorable (9.72e-4)" "potential prognostic favorable (5.06e-4)" "unprognostic (1.14e-3)" "unprognostic (2.52e-2)" "potential prognostic unfavorable (5.37e-4)" "unprognostic (8.71e-2)" "unprognostic (2.16e-1)" "unprognostic (3.50e-2)" "unprognostic (1.23e-1)" "unprognostic (5.01e-2)" "unprognostic (1.63e-3)" "unprognostic (7.49e-2)" "unprognostic (1.85e-2)" "potential prognostic unfavorable (5.27e-4)" "unprognostic (3.26e-2)" "unprognostic (4.42e-2)" "unprognostic (1.38e-1)" "unprognostic (2.10e-1)" "unprognostic (1.30e-1)" "unprognostic (2.75e-1)" "unprognostic (5.74e-2)" "unprognostic (1.30e-1)" UBR7 C14orf130 ENSG00000012963 "Ubiquitin protein ligase E3 component n-recognin 7" Q8N806 14 93207241-93229215 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 16 "Early spermatids: 295.2;Late primary spermatocytes: 158.3;Late spermatids: 477.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000861 Approved Approved Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 34: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 23 Nucleoplasm "HPA000861: " "unprognostic (2.68e-3)" "unprognostic (1.04e-1)" "unprognostic (1.63e-3)" "unprognostic (4.80e-2)" "unprognostic (1.81e-1)" "unprognostic (1.71e-2)" "unprognostic (2.18e-1)" "unprognostic (1.03e-1)" "unprognostic (1.69e-1)" "unprognostic (1.53e-2)" "validated prognostic favorable (4.76e-7)" "validated prognostic favorable (4.73e-4)" "unprognostic (9.75e-3)" "potential prognostic unfavorable (6.28e-4)" "unprognostic (5.90e-3)" "unprognostic (1.62e-1)" "unprognostic (2.29e-2)" "unprognostic (1.05e-1)" "unprognostic (3.02e-1)" "unprognostic (1.89e-1)" "unprognostic (3.87e-2)" "unprognostic (2.71e-1)" "unprognostic (2.50e-1)" "unprognostic (4.12e-2)" "unprognostic (2.14e-1)" "unprognostic (2.31e-1)" "unprognostic (1.93e-2)" "unprognostic (8.69e-2)" "unprognostic (1.13e-1)" "unprognostic (5.83e-2)" "unprognostic (1.04e-1)" UBTD1 FLJ11807 ENSG00000165886 "Ubiquitin domain containing 1" Q9HAC8 10 97498924-97571206 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 109.7;Early spermatids: 97.6;Rod photoreceptor cells: 142.6;Sertoli cells: 113.7;Transitional alveolar cells: 114.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 6.4;neutrophil: 6.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034825 Uncertain Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 47: Testis - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 79: Photoreceptor cells - Phototransduction" 23 Vesicles "Plasma membrane, Cytosol" "HPA034825: " "unprognostic (5.90e-2)" "unprognostic (1.38e-1)" "unprognostic (6.40e-2)" "unprognostic (8.04e-2)" "unprognostic (1.41e-3)" "unprognostic (1.04e-1)" "unprognostic (4.55e-1)" "unprognostic (1.72e-1)" "unprognostic (7.20e-2)" "unprognostic (2.78e-1)" "unprognostic (7.52e-3)" "unprognostic (3.91e-1)" "unprognostic (1.16e-1)" "unprognostic (1.00e-2)" "unprognostic (3.29e-1)" "unprognostic (3.57e-3)" "unprognostic (1.37e-2)" "unprognostic (3.79e-2)" "unprognostic (1.06e-1)" "unprognostic (2.48e-2)" "unprognostic (7.66e-3)" "unprognostic (6.20e-2)" "unprognostic (2.74e-2)" "unprognostic (1.14e-1)" "unprognostic (2.97e-3)" "unprognostic (4.32e-2)" "unprognostic (7.08e-2)" "unprognostic (1.74e-1)" "unprognostic (9.22e-2)" "unprognostic (6.06e-2)" "unprognostic (1.36e-1)" UBTD2 "DC-UbP, MGC30022" ENSG00000168246 "Ubiquitin domain containing 2" Q8WUN7 5 172209646-172283764 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial secretory cells: 268.0" "Cell type enhanced" "Detected in all" "upper rhombic lip: 161.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Prostate - Fibroblasts, Spleen - Fibroblasts_1, Testis - Late spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035891, HPA035892" Uncertain NA NA "Cluster 39: Testis - Nuclear processes" "Cluster 35: Non-specific - DNA binding" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 100: Stratified epithelial cells - Barrier functions" 19 "HPA035891: , HPA035892: " "unprognostic (4.96e-2)" "unprognostic (2.74e-1)" "unprognostic (1.20e-1)" "unprognostic (3.53e-1)" "unprognostic (4.01e-3)" "unprognostic (1.47e-2)" "unprognostic (2.39e-1)" "unprognostic (3.64e-1)" "unprognostic (1.72e-1)" "unprognostic (4.92e-2)" "potential prognostic favorable (3.02e-5)" "unprognostic (4.53e-2)" "unprognostic (3.46e-1)" "potential prognostic unfavorable (2.88e-6)" "unprognostic (4.04e-2)" "unprognostic (1.10e-2)" "unprognostic (7.12e-3)" "unprognostic (1.03e-2)" "unprognostic (3.33e-1)" "unprognostic (3.20e-2)" "unprognostic (1.31e-3)" "unprognostic (5.33e-2)" "unprognostic (6.26e-2)" "unprognostic (4.09e-2)" "unprognostic (1.03e-2)" "unprognostic (1.13e-2)" "unprognostic (6.98e-2)" "unprognostic (3.51e-2)" "unprognostic (1.67e-1)" "unprognostic (3.47e-2)" "unprognostic (1.27e-1)" UBTF "NOR-90, UBF, UBF1, UBF2" ENSG00000108312 "Upstream binding transcription factor" P17480 17 44205033-44221626 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant, Intellectual disability, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 178.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004611, HPA006385" Supported Supported Enhanced "Nucleoli fibrillar center" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 49: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 17: Non-specific - RNA processing" 29 "Nucleoli fibrillar center" "CAB004611: , HPA006385: " "unprognostic (2.86e-2)" "unprognostic (1.15e-1)" "unprognostic (3.37e-1)" "unprognostic (3.58e-2)" "unprognostic (3.01e-1)" "unprognostic (6.02e-2)" "unprognostic (1.40e-1)" "unprognostic (1.16e-3)" "unprognostic (5.74e-2)" "unprognostic (8.94e-2)" "potential prognostic favorable (4.04e-4)" "unprognostic (9.63e-3)" "unprognostic (4.13e-1)" "unprognostic (4.08e-3)" "unprognostic (6.17e-3)" "unprognostic (1.93e-1)" "unprognostic (2.19e-2)" "unprognostic (1.89e-1)" "unprognostic (3.19e-3)" "unprognostic (1.97e-2)" "unprognostic (3.71e-1)" "unprognostic (5.87e-2)" "unprognostic (4.53e-2)" "unprognostic (1.90e-1)" "unprognostic (1.57e-1)" "unprognostic (1.50e-1)" "unprognostic (1.43e-1)" "unprognostic (2.39e-1)" "unprognostic (3.24e-1)" "unprognostic (1.47e-1)" "unprognostic (3.67e-2)" UBTFL1 C11orf27 ENSG00000255009 "Upstream binding transcription factor like 1" P0CB47 11 90085950-90087131 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 1: Neuronal - Visual perception" 22 UBXN1 "2B28, LOC51035, SAKS1, UBXD10" ENSG00000162191 "UBX domain protein 1" Q04323 11 62676498-62679117 "Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 497.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012669, HPA076932" Approved Supported Nucleoplasm,Cytosol NA NA 18000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 24: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 15: Non-specific - Protein processing" 34 Cytosol Nucleoplasm "HPA012669: , HPA076932: " "unprognostic (8.29e-2)" "unprognostic (2.79e-3)" "unprognostic (1.63e-1)" "unprognostic (3.81e-2)" "unprognostic (8.63e-3)" "unprognostic (1.52e-1)" "unprognostic (1.48e-1)" "unprognostic (2.00e-2)" "unprognostic (5.60e-2)" "unprognostic (7.65e-3)" "unprognostic (1.20e-3)" "unprognostic (3.46e-1)" "unprognostic (3.03e-2)" "unprognostic (6.43e-3)" "unprognostic (1.23e-3)" "unprognostic (8.85e-2)" "unprognostic (2.68e-3)" "unprognostic (5.11e-2)" "unprognostic (6.01e-2)" "unprognostic (2.29e-1)" "unprognostic (4.86e-2)" "unprognostic (3.22e-2)" "unprognostic (1.87e-1)" "unprognostic (1.29e-1)" "unprognostic (1.51e-1)" "unprognostic (6.54e-2)" "unprognostic (9.32e-2)" "unprognostic (1.35e-1)" "unprognostic (1.65e-1)" "unprognostic (1.66e-2)" "unprognostic (1.15e-1)" UBXN10 "FLJ25429, UBXD3" ENSG00000162543 "UBX domain protein 10" Q96LJ8 1 20186096-20196050 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 22.4;fallopian tube: 46.8" "Group enriched" "Detected in many" 5 "Early spermatids: 106.0;Endometrial ciliated cells: 87.9;Epididymal efferent duct ciliated cells: 70.1;Fallopian tube ciliated cells: 193.9;Late primary spermatocytes: 147.5;Late spermatids: 207.2;Respiratory ciliated cells: 209.1" "Group enriched" "Detected in many" 4 "Bergmann glia: 10.2;choroid plexus epithelial cell: 13.2;ependymal cell: 31.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 4.1" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Gastric cancer: 3.1" "Adipose subcutaneous - Mast cells, Adipose visceral - Mesothelial cells, Lung - Respiratory ciliated cells, Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA028555, HPA028564" Uncertain NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 70: DU4475 - Unknown function" "Cluster 107: Ciliated cells - Cilia assembly & function" 16 "HPA028555: , HPA028564: " "unprognostic (6.65e-2)" "unprognostic (4.27e-2)" "unprognostic (1.68e-1)" "unprognostic (6.36e-3)" "unprognostic (1.52e-1)" "unprognostic (3.81e-1)" "potential prognostic unfavorable (2.59e-4)" "unprognostic (3.08e-2)" "unprognostic (7.73e-2)" "validated prognostic favorable (1.14e-4)" "validated prognostic favorable (9.02e-5)" "unprognostic (1.38e-2)" "unprognostic (7.60e-2)" "unprognostic (2.84e-2)" "unprognostic (1.78e-1)" "unprognostic (2.89e-1)" "unprognostic (6.10e-2)" "unprognostic (5.62e-2)" "unprognostic (2.18e-1)" "unprognostic (3.68e-2)" "unprognostic (2.13e-2)" "unprognostic (9.44e-3)" "unprognostic (3.14e-1)" "unprognostic (2.30e-2)" "unprognostic (9.57e-2)" "unprognostic (1.32e-1)" "unprognostic (2.30e-2)" "unprognostic (1.43e-1)" "unprognostic (3.63e-2)" UBXN11 "SOC, SOCI, UBXD5" ENSG00000158062 "UBX domain protein 11" Q5T124 1 26281328-26318363 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 131.3;Epididymal efferent duct ciliated cells: 157.4;Epididymal principal cells: 207.4;Fallopian tube ciliated cells: 161.6;Late primary spermatocytes: 117.3;Late spermatids: 542.7;Oocytes: 502.0;Respiratory ciliated cells: 173.2" "Cell type enhanced" "Detected in all" "ependymal cell: 100.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 94.2;intermediate monocyte: 83.1;myeloid DC: 48.8;non-classical monocyte: 73.8" "Group enriched" "Detected in all" 4 "dendritic cells: 48.8;monocytes: 94.2" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028600, HPA031356" Approved Approved "Basal body,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 37: Non-specific - mRNA processing" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 21 "Basal body, Cytosol" "HPA028600: , HPA031356: " "unprognostic (9.05e-2)" "unprognostic (1.16e-3)" "unprognostic (6.10e-2)" "unprognostic (2.65e-2)" "unprognostic (2.47e-1)" "unprognostic (2.11e-1)" "unprognostic (7.32e-2)" "unprognostic (2.44e-1)" "unprognostic (2.02e-2)" "unprognostic (3.74e-2)" "potential prognostic favorable (3.04e-4)" "unprognostic (3.89e-1)" "unprognostic (5.71e-3)" "potential prognostic unfavorable (1.81e-5)" "unprognostic (8.06e-2)" "unprognostic (8.90e-3)" "unprognostic (1.59e-2)" "unprognostic (1.08e-3)" "unprognostic (1.50e-1)" "unprognostic (2.41e-1)" "unprognostic (3.26e-2)" "unprognostic (6.93e-2)" "unprognostic (9.77e-2)" "unprognostic (2.10e-1)" "unprognostic (6.33e-2)" "potential prognostic favorable (3.08e-5)" "unprognostic (4.56e-2)" "unprognostic (1.15e-1)" "unprognostic (2.43e-1)" "unprognostic (2.88e-1)" "unprognostic (6.39e-3)" UBXN2A UBXD4 ENSG00000173960 "UBX domain protein 2A" P68543 2 23927285-24004909 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065482, HPA069096" Supported Approved Centrosome NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 25: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 7: Non-specific - Transcription" 16 Centrosome "HPA065482: , HPA069096: " "unprognostic (4.09e-2)" "unprognostic (1.11e-1)" "unprognostic (8.27e-2)" "unprognostic (1.58e-2)" "unprognostic (3.35e-2)" "unprognostic (1.30e-1)" "unprognostic (1.87e-1)" "unprognostic (1.58e-1)" "unprognostic (1.35e-2)" "unprognostic (1.09e-2)" "unprognostic (7.41e-3)" "unprognostic (7.18e-3)" "unprognostic (4.78e-2)" "potential prognostic unfavorable (9.03e-4)" "unprognostic (4.15e-3)" "unprognostic (4.08e-2)" "unprognostic (2.88e-2)" "unprognostic (3.39e-2)" "unprognostic (4.63e-1)" "unprognostic (1.41e-1)" "unprognostic (1.02e-1)" "unprognostic (3.04e-1)" "potential prognostic unfavorable (3.48e-4)" "unprognostic (3.69e-2)" "unprognostic (6.60e-2)" "unprognostic (1.10e-2)" "unprognostic (2.70e-1)" "unprognostic (1.20e-1)" "unprognostic (2.14e-1)" "unprognostic (4.05e-2)" "unprognostic (4.93e-2)" UBXN2B p37 ENSG00000215114 "UBX domain protein 2B" Q14CS0 8 58411359-58451501 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "Neutrophils: 908.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 42.9" "Group enriched" "Detected in all" 5 "granulocytes: 42.9;monocytes: 13.0" "Low cancer specificity" "Detected in all" "Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045278 Uncertain Approved Nucleoplasm No No "Cluster 28: Neutrophils - Unknown function" "Cluster 36: Brain & Liver - Signaling" "Cluster 31: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" 23 Nucleoplasm "HPA045278: " "unprognostic (7.27e-2)" "unprognostic (3.53e-3)" "unprognostic (9.66e-2)" "unprognostic (1.73e-1)" "unprognostic (7.80e-2)" "unprognostic (3.30e-1)" "unprognostic (3.26e-2)" "unprognostic (1.17e-1)" "unprognostic (1.34e-1)" "unprognostic (1.83e-2)" "potential prognostic favorable (1.24e-5)" "unprognostic (7.18e-2)" "unprognostic (9.17e-2)" "unprognostic (3.45e-1)" "unprognostic (1.29e-1)" "unprognostic (2.43e-1)" "unprognostic (1.71e-2)" "unprognostic (6.51e-2)" "unprognostic (1.37e-1)" "unprognostic (1.22e-1)" "unprognostic (4.88e-2)" "unprognostic (2.99e-2)" "unprognostic (3.23e-1)" "unprognostic (1.83e-1)" "unprognostic (3.28e-2)" "unprognostic (4.19e-2)" "unprognostic (4.23e-1)" "unprognostic (4.71e-2)" "unprognostic (2.79e-1)" "unprognostic (9.96e-2)" "unprognostic (5.56e-1)" UBXN4 "KIAA0242, UBXD2, UBXDC1" ENSG00000144224 "UBX domain protein 4" Q92575 2 135741734-135785056 "Predicted intracellular proteins, Predicted membrane proteins" "Unfolded protein response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 1092.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036325 Approved Supported "Endoplasmic reticulum" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 30 "Endoplasmic reticulum" "HPA036325: " "unprognostic (4.66e-1)" "unprognostic (1.19e-2)" "unprognostic (3.22e-3)" "unprognostic (1.76e-1)" "unprognostic (1.02e-1)" "unprognostic (2.85e-1)" "unprognostic (8.71e-2)" "unprognostic (2.51e-2)" "unprognostic (1.46e-1)" "unprognostic (2.18e-2)" "potential prognostic favorable (1.25e-6)" "unprognostic (1.11e-1)" "unprognostic (3.48e-2)" "unprognostic (2.69e-1)" "unprognostic (2.09e-1)" "unprognostic (9.88e-2)" "unprognostic (1.84e-1)" "unprognostic (1.49e-1)" "unprognostic (2.07e-2)" "unprognostic (1.26e-1)" "unprognostic (2.36e-2)" "unprognostic (1.19e-2)" "unprognostic (1.67e-2)" "unprognostic (2.25e-1)" "unprognostic (1.27e-1)" "unprognostic (2.75e-1)" "unprognostic (1.07e-1)" "unprognostic (3.13e-1)" "unprognostic (2.93e-1)" "unprognostic (6.22e-2)" "unprognostic (1.03e-1)" UBXN6 "UBXD1, UBXDC2" ENSG00000167671 "UBX domain protein 6" Q9BZV1 19 4444999-4457794 "Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 7 "Late spermatids: 2483.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040906, HPA041313, HPA061872" Approved Approved "Golgi apparatus,Cytosol" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 24: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 179 "Golgi apparatus, Cytosol" "HPA040906: , HPA041313: , HPA061872: " "unprognostic (1.16e-2)" "unprognostic (4.30e-1)" "unprognostic (2.61e-2)" "unprognostic (1.74e-1)" "unprognostic (1.31e-1)" "unprognostic (1.62e-1)" "unprognostic (2.82e-1)" "unprognostic (1.36e-1)" "unprognostic (2.92e-2)" "unprognostic (5.34e-2)" "potential prognostic favorable (6.52e-7)" "unprognostic (2.34e-2)" "unprognostic (7.02e-3)" "unprognostic (5.68e-3)" "unprognostic (2.42e-2)" "unprognostic (4.98e-2)" "unprognostic (1.78e-1)" "unprognostic (3.20e-1)" "unprognostic (4.61e-1)" "unprognostic (1.97e-1)" "unprognostic (8.50e-2)" "unprognostic (1.06e-2)" "unprognostic (2.35e-1)" "unprognostic (5.78e-2)" "unprognostic (8.80e-2)" "unprognostic (1.27e-1)" "unprognostic (1.55e-1)" "unprognostic (2.28e-1)" "unprognostic (4.46e-2)" "unprognostic (1.59e-1)" "unprognostic (1.81e-2)" UBXN7 "KIAA0794, UBXD7" ENSG00000163960 "UBX domain protein 7" O94888 3 196347662-196432430 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skeletal muscle - Endothelial cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "HPA048441, HPA049442" Supported Enhanced Nucleoplasm NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 61: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 63: Non-specific - Protein processing" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 66 Nucleoplasm "HPA048441: , HPA049442: " "unprognostic (7.38e-2)" "unprognostic (5.40e-3)" "unprognostic (1.14e-1)" "unprognostic (1.95e-1)" "unprognostic (1.43e-2)" "unprognostic (1.64e-1)" "unprognostic (2.08e-1)" "unprognostic (2.14e-2)" "unprognostic (2.33e-1)" "potential prognostic unfavorable (3.42e-4)" "unprognostic (1.46e-3)" "unprognostic (1.59e-2)" "unprognostic (4.57e-2)" "unprognostic (1.14e-3)" "unprognostic (6.06e-2)" "unprognostic (1.91e-2)" "unprognostic (6.62e-3)" "unprognostic (9.10e-2)" "unprognostic (1.19e-1)" "unprognostic (1.36e-2)" "unprognostic (4.58e-3)" "unprognostic (6.22e-2)" "potential prognostic unfavorable (8.57e-5)" "unprognostic (3.65e-2)" "unprognostic (2.67e-2)" "unprognostic (1.29e-1)" "unprognostic (4.71e-2)" "unprognostic (6.15e-2)" "unprognostic (3.02e-1)" "unprognostic (3.24e-2)" "unprognostic (1.66e-1)" UBXN8 "D8S2298E, REP8, UBXD6" ENSG00000104691 "UBX domain protein 8" O00124 8 30729131-30767006 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 117.0" "Cell type enhanced" "Detected in many" "Early spermatids: 241.0;Granulosa cells: 364.9;Hepatocytes: 89.2;Late spermatids: 290.5;Ovarian stromal cells: 152.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017725, HPA077538" Enhanced Supported "Nucleoplasm,Nucleoli,Endoplasmic reticulum" "Intracellular and membrane" "No annotated function" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 75: Ovary - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 94: Gonadal somatic cells - Mixed function" 12 "Endoplasmic reticulum" "Nucleoplasm, Nucleoli" "HPA017725: , HPA077538: " "unprognostic (5.09e-2)" "unprognostic (9.91e-2)" "unprognostic (1.01e-1)" "unprognostic (6.96e-3)" "potential prognostic favorable (9.67e-4)" "unprognostic (1.66e-1)" "unprognostic (2.49e-1)" "unprognostic (2.88e-1)" "unprognostic (1.06e-1)" "unprognostic (4.09e-2)" "potential prognostic favorable (6.95e-6)" "unprognostic (1.02e-2)" "unprognostic (8.47e-2)" "unprognostic (6.47e-2)" "unprognostic (1.60e-2)" "unprognostic (3.87e-1)" "unprognostic (1.30e-1)" "unprognostic (3.21e-2)" "unprognostic (5.65e-2)" "unprognostic (1.69e-1)" "unprognostic (8.17e-2)" "unprognostic (2.84e-1)" "unprognostic (5.46e-2)" "unprognostic (1.31e-2)" "unprognostic (2.80e-3)" "unprognostic (8.89e-2)" "unprognostic (2.83e-1)" "unprognostic (6.71e-2)" "unprognostic (2.74e-1)" "unprognostic (3.26e-1)" "unprognostic (3.69e-1)" UCHL1 "PARK5, PGP9.5, Uch-L1, UCHL-1" ENSG00000154277 "Ubiquitin C-terminal hydrolase L1" P09936 4 41256413-41268455 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 1037.7;pituitary gland: 337.4" "Cell type enriched" "Detected in many" 4 "Oocytes: 2030.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 316.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002580, HPA005993, CAB079024" Enhanced Supported Supported Nucleoplasm,Cytosol NA NA 80000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 78: Brain - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 98: Neurons - Neurotransmission & signaling" 66 Cytosol Nucleoplasm "CAB002580: , CAB079024: , HPA005993: " "unprognostic (3.80e-2)" "unprognostic (6.52e-2)" "unprognostic (7.58e-2)" "unprognostic (5.74e-2)" "unprognostic (2.43e-2)" "unprognostic (3.10e-2)" "unprognostic (1.62e-1)" "unprognostic (2.34e-1)" "unprognostic (2.48e-1)" "unprognostic (4.23e-1)" "potential prognostic unfavorable (4.40e-6)" "unprognostic (3.61e-3)" "unprognostic (2.33e-2)" "potential prognostic unfavorable (1.83e-4)" "unprognostic (5.55e-2)" "unprognostic (3.55e-2)" "unprognostic (2.72e-1)" "unprognostic (2.46e-1)" "potential prognostic favorable (7.61e-4)" "unprognostic (1.44e-2)" "unprognostic (1.46e-1)" "unprognostic (2.06e-3)" "unprognostic (1.45e-1)" "unprognostic (1.69e-1)" "unprognostic (3.25e-1)" "unprognostic (1.22e-1)" "unprognostic (1.04e-1)" "unprognostic (2.67e-2)" "unprognostic (2.77e-2)" "unprognostic (7.26e-3)" "unprognostic (5.19e-3)" UCHL3 ENSG00000118939 "Ubiquitin C-terminal hydrolase L3" P15374 13 75549480-75606020 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 170.6;Esophageal apical cells: 160.9;Esophageal basal cells: 133.3;Esophageal suprabasal cells: 203.6;Extravillous trophoblasts: 166.2;Late primary spermatocytes: 312.8;Syncytiotrophoblasts: 186.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019678, CAB037139, CAB037208" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" No No 670000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 76: Non-specific - Metabolism" "Cluster 33: Neurons - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 85: Squamous epithelial cells - Keratinization" 22 "Nucleoplasm, Cytosol" "Golgi apparatus" "CAB037139: , CAB037208: , HPA019678: " "unprognostic (1.98e-1)" "unprognostic (1.95e-1)" "unprognostic (3.03e-1)" "unprognostic (1.99e-1)" "unprognostic (8.49e-2)" "unprognostic (1.14e-1)" "unprognostic (1.67e-2)" "unprognostic (1.18e-1)" "unprognostic (5.40e-3)" "unprognostic (1.05e-1)" "potential prognostic favorable (8.44e-5)" "unprognostic (8.65e-2)" "unprognostic (4.58e-3)" "unprognostic (1.13e-2)" "potential prognostic unfavorable (8.45e-4)" "unprognostic (5.41e-3)" "potential prognostic unfavorable (2.15e-5)" "unprognostic (2.86e-1)" "unprognostic (4.37e-2)" "unprognostic (1.88e-1)" "unprognostic (3.41e-2)" "unprognostic (1.86e-2)" "unprognostic (1.60e-1)" "unprognostic (4.84e-2)" "unprognostic (7.38e-2)" "unprognostic (1.60e-1)" "unprognostic (2.44e-2)" "unprognostic (5.04e-1)" "unprognostic (2.52e-1)" "unprognostic (2.49e-2)" "unprognostic (1.24e-1)" UCHL5 "CGI-70, INO80R, UCH37" ENSG00000116750 "Ubiquitin C-terminal hydrolase L5" Q9Y5K5 1 193012250-193060080 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 168.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005908, HPA006069" Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA 16000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 162 "Nucleoplasm, Cytosol" Nucleoli "HPA005908: , HPA006069: " "unprognostic (1.57e-1)" "unprognostic (2.66e-2)" "unprognostic (1.32e-1)" "unprognostic (1.18e-2)" "unprognostic (3.35e-2)" "unprognostic (5.51e-2)" "unprognostic (8.07e-2)" "unprognostic (1.19e-1)" "unprognostic (1.18e-1)" "unprognostic (2.48e-3)" "potential prognostic favorable (4.55e-5)" "unprognostic (6.11e-2)" "unprognostic (2.22e-3)" "unprognostic (2.32e-2)" "unprognostic (3.14e-2)" "unprognostic (4.86e-3)" "unprognostic (1.87e-2)" "unprognostic (4.27e-1)" "unprognostic (3.25e-1)" "unprognostic (1.47e-1)" "unprognostic (6.52e-2)" "potential prognostic unfavorable (2.07e-4)" "unprognostic (1.62e-2)" "unprognostic (9.00e-2)" "unprognostic (1.46e-1)" "unprognostic (2.48e-3)" "potential prognostic unfavorable (6.96e-4)" "unprognostic (2.45e-1)" "unprognostic (1.95e-1)" "potential prognostic unfavorable (1.24e-6)" "unprognostic (4.72e-1)" UCK1 "FLJ12255, URK1" ENSG00000130717 "Uridine-cytidine kinase 1" Q9HA47 9 131523801-131531264 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 50.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050969, HPA070526" Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 24: Non-specific - Transcription" "Cluster 19: Astrocytes - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 7 Nucleoplasm Nucleoli "HPA050969: , HPA070526: " "unprognostic (3.06e-2)" "unprognostic (9.05e-2)" "unprognostic (4.71e-2)" "unprognostic (6.17e-2)" "unprognostic (6.25e-2)" "unprognostic (1.01e-1)" "unprognostic (1.61e-1)" "unprognostic (8.05e-3)" "unprognostic (1.46e-1)" "unprognostic (1.33e-1)" "potential prognostic favorable (5.33e-6)" "unprognostic (2.36e-3)" "unprognostic (1.10e-3)" "unprognostic (5.43e-2)" "unprognostic (1.28e-1)" "unprognostic (2.34e-1)" "unprognostic (4.11e-1)" "unprognostic (2.08e-2)" "unprognostic (6.72e-3)" "unprognostic (8.60e-2)" "unprognostic (1.67e-1)" "unprognostic (3.73e-2)" "unprognostic (1.18e-1)" "unprognostic (2.66e-1)" "unprognostic (2.26e-1)" "unprognostic (2.80e-1)" "unprognostic (1.61e-1)" "unprognostic (2.19e-1)" "unprognostic (2.75e-2)" "unprognostic (5.58e-2)" "unprognostic (3.83e-2)" UCK2 UMPK ENSG00000143179 "Uridine-cytidine kinase 2" Q9BZX2 1 165827614-165911618 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bergmann glia: 160.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Corticotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057128, HPA078645" Approved Nucleoplasm,Cytosol NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 1: Neurons - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 14 Nucleoplasm Cytosol "HPA057128: , HPA078645: " "potential prognostic unfavorable (6.38e-5)" "unprognostic (2.16e-2)" "unprognostic (1.17e-1)" "unprognostic (1.32e-1)" "unprognostic (7.32e-2)" "unprognostic (2.06e-1)" "unprognostic (2.20e-1)" "unprognostic (1.17e-3)" "unprognostic (2.44e-3)" "unprognostic (6.86e-2)" "potential prognostic unfavorable (2.68e-4)" "unprognostic (2.06e-1)" "potential prognostic unfavorable (1.45e-7)" "validated prognostic unfavorable (4.58e-10)" "validated prognostic unfavorable (4.54e-6)" "potential prognostic unfavorable (1.15e-6)" "unprognostic (2.00e-2)" "unprognostic (5.13e-2)" "unprognostic (4.28e-2)" "unprognostic (2.03e-2)" "unprognostic (9.78e-2)" "potential prognostic unfavorable (7.13e-4)" "unprognostic (2.30e-1)" "unprognostic (6.21e-2)" "unprognostic (7.40e-2)" "unprognostic (2.21e-1)" "potential prognostic unfavorable (1.26e-4)" "unprognostic (1.29e-1)" "unprognostic (1.85e-1)" "unprognostic (1.69e-2)" "unprognostic (1.66e-1)" UCKL1 "FLJ20517, URKL1" ENSG00000198276 "Uridine-cytidine kinase 1 like 1" Q9NWZ5 20 63939829-63956416 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Host-virus interaction" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 97.3;Rod photoreceptor cells: 121.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004722, HPA004769" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 62: Non-specific - Plasma proteins" "Cluster 79: Photoreceptor cells - Phototransduction" 15 "Endoplasmic reticulum" "HPA004722: , HPA004769: " "unprognostic (3.16e-1)" "unprognostic (1.32e-2)" "unprognostic (2.81e-1)" "unprognostic (5.20e-2)" "unprognostic (2.85e-1)" "unprognostic (7.31e-2)" "unprognostic (2.08e-1)" "unprognostic (7.23e-2)" "unprognostic (1.95e-1)" "unprognostic (3.80e-2)" "unprognostic (2.16e-2)" "unprognostic (4.26e-1)" "unprognostic (5.03e-3)" "potential prognostic unfavorable (4.57e-4)" "unprognostic (3.46e-2)" "unprognostic (1.13e-2)" "unprognostic (2.79e-1)" "unprognostic (1.86e-1)" "unprognostic (4.22e-2)" "unprognostic (1.35e-1)" "unprognostic (8.03e-2)" "potential prognostic favorable (6.72e-4)" "unprognostic (3.73e-3)" "unprognostic (2.78e-2)" "unprognostic (6.87e-3)" "unprognostic (7.26e-3)" "unprognostic (2.61e-2)" "unprognostic (2.83e-1)" "unprognostic (2.27e-1)" "unprognostic (1.06e-2)" "unprognostic (1.42e-2)" UCMA "C10orf49, GRP" ENSG00000165623 "Upper zone of growth plate and cartilage matrix associated" Q8WVF2 10 13221766-13234374 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 2.6" "Cell type enriched" "Detected in some" 121 "Oocytes: 156.6" "Cell type enriched" "Detected in single" 10 "deep-layer intratelencephalic: 1.6" "Cancer enhanced" "Detected in single" "Uterine Corpus Endometrial Carcinoma (TCGA): 1.3" "Group enriched" "Detected in some" 18 "amygdala: 2.1;cerebral cortex: 4.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA046718 Uncertain "Secreted to extracellular matrix" "No annotated function" NA NA "Cluster 65: Brain - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 41: Oocytes - Oogenesis" "HPA046718: " "unprognostic (2.25e-1)" UCN "UCN1, UI, UROC" ENSG00000163794 Urocortin P55089 2 27307400-27308445 "Predicted secreted proteins" Hearing Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 9.2" "Cell type enhanced" "Detected in many" "Astrocytes: 8.5;Bergmann glia: 5.8;Brain excitatory neurons: 7.5;Brain inhibitory neurons: 9.2;Cardiomyocytes: 9.4;Oligodendrocytes: 9.4;Other brain neurons: 5.9;Pancreatic acinar cells: 13.8;Sertoli cells: 9.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "spinal cord: 3.3" "CAB010911, HPA069971" Approved Approved "Vesicles,Plasma membrane" "Secreted to blood" Hormone NA NA 133000 "Cluster 78: Brain - Neuronal signaling" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 109: Neurons - Neuronal signaling" 2 Vesicles "Plasma membrane" "CAB010911: , HPA069971: " "unprognostic (2.86e-2)" "unprognostic (4.97e-2)" "unprognostic (1.32e-1)" "unprognostic (1.05e-2)" "unprognostic (1.58e-3)" "unprognostic (2.39e-1)" "unprognostic (2.58e-2)" "potential prognostic favorable (1.59e-4)" "unprognostic (2.09e-2)" "potential prognostic unfavorable (2.32e-10)" "unprognostic (4.04e-3)" "unprognostic (3.52e-1)" "unprognostic (1.65e-3)" "unprognostic (4.06e-2)" "unprognostic (2.64e-1)" "unprognostic (1.10e-1)" "unprognostic (9.37e-2)" "unprognostic (2.16e-1)" "unprognostic (3.39e-2)" "unprognostic (2.87e-2)" "unprognostic (5.69e-2)" "unprognostic (1.67e-1)" "unprognostic (1.32e-1)" "unprognostic (1.25e-1)" "unprognostic (5.36e-2)" "unprognostic (1.54e-1)" "unprognostic (1.99e-1)" "unprognostic (1.44e-1)" UCN2 "SRP, UCN-II, UCNI, URP" ENSG00000145040 "Urocortin 2" Q96RP3 3 48561718-48563781 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skin 1: 12.4" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 3.2;Epididymal basal cells: 1.7;Gastric progenitor cells: 1.3;Ocular epithelial cells: 1.2;Schwann cells: 5.5;Thymic myoid cells: 1.4" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Skin Cutaneous Melanoma (TCGA): 36.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 8 "skin cancer: 119.2" "Minor Salivary Gland - Minor salivary gland basal cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA066841 Uncertain Approved Vesicles "Secreted to blood" Hormone NA NA 98600 "Cluster 37: Skin - Keratinization" "Cluster 69: Skin cancer - ECM organization" "Cluster 26: Keratinocytes - Keratinization" Vesicles "HPA066841: " "unprognostic (3.52e-1)" "unprognostic (1.44e-3)" "unprognostic (2.34e-1)" "unprognostic (3.91e-2)" "unprognostic (1.68e-1)" "unprognostic (8.61e-2)" "unprognostic (1.13e-1)" "unprognostic (1.02e-1)" "unprognostic (1.57e-3)" "unprognostic (4.10e-2)" "unprognostic (1.93e-1)" "unprognostic (5.37e-1)" UCN3 "SPC, UCNIII" ENSG00000178473 "Urocortin 3" Q969E3 10 5364966-5374692 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 8.2;pancreas: 5.4;pituitary gland: 2.6;stomach 1: 3.2" "Cell type enriched" "Detected in some" 5 "Neuroendocrine cells: 212.0" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Lung Adenocarcinoma (TCGA): 12.9;Pancreatic Adenocarcinoma (TCGA): 21.3;Stomach Adenocarcinoma (TCGA): 5.9" "Group enriched" "Detected in some" 7 "basal ganglia: 2.5;hypothalamus: 1.7;medulla oblongata: 4.1;midbrain: 1.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "breast cancer: 1.1;lung cancer: 3.0;pancreatic cancer: 1.0;thyroid cancer: 3.2" "Adrenal gland - Adrenal medulla cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Pancreas - Alpha cells, Pancreas - Beta cells" "Region enhanced" "Detected in some" "hypothalamus: 5.1" HPA038281 Uncertain "Secreted to blood" Hormone NA NA "Cluster 60: Stomach - Digestion" "Cluster 43: Hindbrain - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" 6 "HPA038281: " "unprognostic (3.20e-3)" "unprognostic (2.93e-1)" "unprognostic (2.52e-2)" "unprognostic (6.49e-2)" "unprognostic (1.40e-1)" "unprognostic (5.49e-2)" "unprognostic (1.62e-3)" "unprognostic (1.82e-1)" "unprognostic (9.76e-2)" "unprognostic (1.48e-1)" "unprognostic (3.55e-2)" UCP1 "SLC25A7, UCP" ENSG00000109424 "Uncoupling protein 1" P25874 4 140559431-140568961 "Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Diabetes mellitus, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "adrenal gland: 2.6" "Cell type enhanced" "Detected in some" "Adipocytes: 4.2;Breast hormone-responsive cells: 1.7;Cardiomyocytes: 5.1;Cytotrophoblasts: 1.9;Granulosa cells: 2.4;Müller glia: 1.8;Retinal ganglion cells: 3.9;Syncytiotrophoblasts: 3.0;Thymocytes: 2.5" "Cell type enhanced" "Detected in some" "upper rhombic lip: 2.8" "Cancer enriched" "Detected in single" 5 "Breast Invasive Carcinoma (TCGA): 1.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Uterine cancer: 1.1" "Not detected" "Not detected" "HPA012022, CAB037199, HPA068364" Supported NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 2: Neurons - Nucleosome" "Cluster 34: Testis cancer - Unknown function" "Cluster 65: Non-specific - Cell growth & division" "CAB037199: , HPA012022: , HPA068364: " "unprognostic (1.33e-1)" "unprognostic (7.35e-2)" UCP2 "BMIQ4, SLC25A8" ENSG00000175567 "Uncoupling protein 2" P55851 11 73974672-73982843 "Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 260.0" "Cell type enhanced" "Detected in many" "cDC: 182.9;Fallopian tube ciliated cells: 230.7;Hofbauer cells: 658.5;Kupffer cells: 370.0;monocytes: 192.5;Neuroendocrine cells: 201.4;pDCs: 346.4;Platelets: 332.4;Respiratory ciliated cells: 202.9" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 33.3;leukocyte: 61.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "lymphoma: 295.4" "Adipose subcutaneous - Macrophages, Adipose visceral - Adipocytes (Visceral), Liver - Kupffer cells, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025583, HPA075202" Approved Supported Mitochondria NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 2 Mitochondria "CAB025583: , HPA075202: " "unprognostic (1.44e-2)" "unprognostic (3.46e-2)" "unprognostic (5.88e-2)" "potential prognostic favorable (6.93e-5)" "unprognostic (5.86e-2)" "unprognostic (8.61e-2)" "unprognostic (4.12e-2)" "unprognostic (8.83e-2)" "unprognostic (2.05e-2)" "unprognostic (7.23e-2)" "unprognostic (6.17e-2)" "unprognostic (1.46e-1)" "potential prognostic unfavorable (8.10e-4)" "unprognostic (1.01e-1)" "unprognostic (9.76e-2)" "unprognostic (5.42e-3)" "unprognostic (7.86e-3)" "unprognostic (2.67e-1)" "unprognostic (2.15e-1)" "unprognostic (7.20e-2)" "unprognostic (1.62e-2)" "unprognostic (2.81e-3)" "unprognostic (9.79e-2)" "unprognostic (1.70e-1)" "unprognostic (1.14e-2)" "unprognostic (3.03e-2)" "unprognostic (1.85e-1)" "unprognostic (5.97e-2)" "unprognostic (6.70e-2)" "unprognostic (1.69e-2)" "unprognostic (2.43e-1)" UCP3 SLC25A9 ENSG00000175564 "Uncoupling protein 3" P55916 11 74000277-74009085 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" Transport "Diabetes mellitus, Disease variant, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 62 "skeletal muscle: 393.6;tongue: 245.8" "Group enriched" "Detected in many" 7 "Early spermatids: 19.8;Late spermatids: 20.2;Myonuclei: 34.4;Thymic myoid cells: 58.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Not detected" "Not detected" "CAB010771, HPA072225" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 48: Non-specific - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 2 "Nucleoplasm, Cytosol" "Plasma membrane" "CAB010771: , HPA072225: " "unprognostic (2.48e-2)" "unprognostic (7.20e-3)" "unprognostic (1.68e-1)" "unprognostic (9.87e-2)" "unprognostic (9.27e-2)" "unprognostic (7.06e-2)" "unprognostic (2.84e-3)" "unprognostic (6.30e-3)" "unprognostic (5.21e-2)" "unprognostic (9.55e-3)" "unprognostic (2.45e-1)" "potential prognostic unfavorable (4.56e-4)" "unprognostic (1.26e-1)" "unprognostic (3.81e-1)" "unprognostic (2.08e-1)" UEVLD "Attp, UEV3" ENSG00000151116 "UEV and lactate/malate dehyrogenase domains" Q8IX04 11 18529609-18588747 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047134 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 24: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 3 Nucleoplasm Cytosol "HPA047134: " "unprognostic (5.36e-2)" "unprognostic (4.13e-2)" "unprognostic (2.42e-1)" "unprognostic (1.71e-2)" "unprognostic (1.65e-2)" "unprognostic (1.69e-2)" "unprognostic (1.14e-1)" "potential prognostic unfavorable (1.62e-4)" "unprognostic (4.06e-1)" "potential prognostic unfavorable (4.00e-4)" "potential prognostic favorable (8.15e-5)" "unprognostic (6.56e-3)" "unprognostic (1.31e-1)" "potential prognostic unfavorable (7.90e-4)" "unprognostic (7.75e-2)" "unprognostic (3.41e-2)" "unprognostic (1.36e-1)" "unprognostic (7.82e-3)" "unprognostic (1.49e-2)" "unprognostic (1.03e-1)" "potential prognostic unfavorable (4.77e-5)" "unprognostic (3.07e-3)" "unprognostic (2.13e-1)" "unprognostic (1.77e-1)" "unprognostic (1.65e-2)" "unprognostic (2.54e-1)" "unprognostic (7.83e-2)" "unprognostic (1.88e-1)" "unprognostic (4.62e-2)" "unprognostic (3.35e-2)" "unprognostic (1.65e-1)" UFC1 HSPC155 ENSG00000143222 "Ubiquitin-fold modifier conjugating enzyme 1" Q9Y3C8 1 161152776-161158856 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 774.5;Extravillous trophoblasts: 513.0;Fallopian tube ciliated cells: 596.0;Late spermatids: 636.7;Respiratory ciliated cells: 748.5;Syncytiotrophoblasts: 551.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027481, HPA028722" Enhanced Approved "Nuclear speckles,Cytosol" NA NA 65000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 70: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 45: Non-specific - Nuclear processes" "Cluster 107: Ciliated cells - Cilia assembly & function" 22 "Nuclear speckles" Cytosol "HPA027481: , HPA028722: " "unprognostic (2.40e-1)" "unprognostic (7.12e-2)" "unprognostic (1.12e-1)" "unprognostic (6.02e-2)" "unprognostic (1.48e-1)" "unprognostic (1.97e-1)" "unprognostic (1.39e-1)" "unprognostic (2.96e-3)" "unprognostic (3.34e-2)" "unprognostic (9.32e-3)" "unprognostic (3.03e-3)" "unprognostic (1.45e-1)" "unprognostic (2.59e-1)" "unprognostic (1.72e-3)" "unprognostic (7.62e-3)" "unprognostic (1.22e-1)" "unprognostic (4.98e-3)" "unprognostic (1.17e-1)" "unprognostic (2.93e-2)" "unprognostic (6.96e-3)" "unprognostic (3.06e-1)" "unprognostic (1.27e-1)" "unprognostic (7.03e-2)" "unprognostic (2.77e-1)" "unprognostic (1.71e-1)" "unprognostic (7.32e-3)" "unprognostic (1.87e-1)" "unprognostic (1.53e-1)" "unprognostic (1.24e-1)" "unprognostic (2.93e-1)" "unprognostic (3.16e-2)" UFD1 UFD1L ENSG00000070010 "Ubiquitin recognition factor in ER associated degradation 1" Q92890 22 19449911-19479202 "Essential proteins, Predicted intracellular proteins, Transporters" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 386.3;Late spermatids: 335.7;Syncytiotrophoblasts: 221.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030286, HPA030287" Approved Approved Nucleoplasm,Nucleoli,Cytosol NA NA 6300 "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 30 "Nucleoplasm, Cytosol" Nucleoli "HPA030286: , HPA030287: " "unprognostic (1.69e-3)" "unprognostic (8.42e-3)" "unprognostic (1.24e-2)" "potential prognostic favorable (8.95e-4)" "unprognostic (6.81e-2)" "unprognostic (3.49e-1)" "unprognostic (4.93e-3)" "unprognostic (5.29e-3)" "potential prognostic unfavorable (2.39e-5)" "potential prognostic favorable (6.91e-4)" "unprognostic (4.34e-3)" "unprognostic (1.27e-1)" "potential prognostic unfavorable (8.57e-4)" "potential prognostic unfavorable (1.20e-4)" "unprognostic (1.87e-1)" "unprognostic (2.66e-2)" "unprognostic (1.06e-2)" "unprognostic (2.30e-2)" "unprognostic (1.94e-1)" "unprognostic (3.16e-3)" "unprognostic (1.17e-2)" "unprognostic (5.90e-2)" "unprognostic (3.84e-2)" "unprognostic (1.70e-2)" "unprognostic (1.02e-1)" "unprognostic (2.35e-2)" "unprognostic (1.38e-1)" "unprognostic (2.98e-1)" "unprognostic (1.03e-1)" UFL1 "KIAA0776, Maxer, NLBP, RCAD" ENSG00000014123 "UFM1 specific ligase 1" O94874 6 96521595-96555276 "Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030558, HPA030559, HPA030560" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 8: Non-specific - Secretory pathway" 61 "Endoplasmic reticulum" "HPA030558: , HPA030559: , HPA030560: " "unprognostic (3.40e-1)" "unprognostic (1.59e-2)" "unprognostic (1.31e-2)" "unprognostic (2.07e-1)" "unprognostic (5.39e-2)" "unprognostic (1.61e-1)" "unprognostic (1.69e-2)" "unprognostic (2.07e-1)" "unprognostic (2.94e-2)" "potential prognostic favorable (2.23e-5)" "unprognostic (8.28e-3)" "unprognostic (1.79e-2)" "unprognostic (1.26e-1)" "unprognostic (6.56e-2)" "unprognostic (1.75e-1)" "unprognostic (2.37e-1)" "unprognostic (1.46e-1)" "unprognostic (3.47e-1)" "unprognostic (1.97e-2)" "unprognostic (3.07e-1)" "unprognostic (3.00e-2)" "unprognostic (2.91e-1)" "unprognostic (2.20e-2)" "unprognostic (3.34e-1)" "unprognostic (1.09e-1)" "unprognostic (1.74e-1)" "unprognostic (2.70e-1)" "unprognostic (2.89e-1)" "unprognostic (2.23e-1)" UFM1 "bA131P10.1, C13orf20" ENSG00000120686 "Ubiquitin fold modifier 1" P61960 13 38349849-38363619 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039758 Approved NA NA 140000 "Cluster 32: Basophils - Transcription" "Cluster 22: Epididymis - Mixed function" "Cluster 7: Non-specific - Ribosome" "Cluster 19: Non-specific - Unknown function" "Cluster 67: Plasma cells - Plasma cell differentiation" 26 "HPA039758: " "unprognostic (2.48e-3)" "unprognostic (1.93e-2)" "unprognostic (7.09e-2)" "unprognostic (5.36e-3)" "unprognostic (1.90e-1)" "unprognostic (1.80e-1)" "unprognostic (4.63e-1)" "potential prognostic unfavorable (6.09e-5)" "potential prognostic unfavorable (5.90e-4)" "unprognostic (1.12e-2)" "potential prognostic favorable (1.55e-7)" "unprognostic (2.46e-2)" "unprognostic (4.00e-1)" "unprognostic (1.46e-3)" "unprognostic (1.81e-2)" "unprognostic (8.35e-2)" "unprognostic (1.38e-2)" "unprognostic (3.79e-2)" "unprognostic (9.33e-2)" "unprognostic (1.23e-1)" "unprognostic (1.39e-2)" "unprognostic (2.05e-2)" "unprognostic (1.26e-1)" "unprognostic (1.42e-1)" "unprognostic (6.33e-2)" "unprognostic (3.03e-1)" "unprognostic (3.63e-2)" "unprognostic (8.01e-2)" "unprognostic (4.15e-2)" "unprognostic (3.86e-2)" "unprognostic (1.22e-1)" UFSP1 UFSP ENSG00000176125 "UFM1 specific peptidase 1 (inactive)" Q6NVU6 7 100888721-100889715 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 10.6;Epididymal clear cells: 6.1;Epididymal principal cells: 12.4;Hepatic stellate cells: 6.5" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027099 Uncertain NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 24: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 39: Non-specific - Transcription" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 32 "HPA027099: " "unprognostic (6.97e-3)" "unprognostic (2.89e-1)" "unprognostic (1.10e-2)" "unprognostic (1.00e-1)" "unprognostic (3.81e-2)" "unprognostic (3.46e-1)" "potential prognostic unfavorable (8.47e-4)" "unprognostic (7.14e-2)" "unprognostic (3.16e-1)" "unprognostic (1.19e-1)" "unprognostic (6.06e-3)" "unprognostic (2.91e-2)" "unprognostic (9.35e-2)" "unprognostic (2.17e-1)" "unprognostic (6.24e-2)" "unprognostic (7.63e-2)" "unprognostic (2.71e-1)" "unprognostic (1.00e-2)" "unprognostic (1.40e-1)" "unprognostic (7.47e-2)" "unprognostic (1.56e-3)" "unprognostic (1.09e-1)" "unprognostic (2.58e-1)" "unprognostic (2.12e-1)" "unprognostic (1.04e-1)" "unprognostic (2.13e-1)" "unprognostic (1.17e-1)" "unprognostic (2.01e-1)" "unprognostic (2.50e-1)" "unprognostic (1.02e-1)" UFSP2 "C4orf20, FLJ11200" ENSG00000109775 "UFM1 specific peptidase 2" Q9NUQ7 4 185399537-185425979 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Disease variant, Dwarfism, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epicardial cells: 213.8;Late primary spermatocytes: 263.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039985, HPA043298" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 38 "Nucleoplasm, Cytosol" "HPA039985: , HPA043298: " "unprognostic (1.47e-1)" "unprognostic (9.61e-2)" "unprognostic (2.10e-1)" "unprognostic (1.64e-1)" "unprognostic (1.38e-1)" "potential prognostic favorable (3.47e-5)" "unprognostic (1.95e-1)" "unprognostic (9.87e-2)" "unprognostic (1.86e-2)" "unprognostic (2.05e-1)" "validated prognostic favorable (3.19e-8)" "validated prognostic favorable (8.81e-5)" "potential prognostic favorable (5.33e-4)" "unprognostic (6.70e-2)" "unprognostic (3.52e-1)" "unprognostic (1.72e-1)" "unprognostic (1.39e-1)" "unprognostic (3.81e-1)" "unprognostic (3.09e-1)" "unprognostic (4.07e-2)" "unprognostic (2.65e-2)" "unprognostic (4.81e-2)" "unprognostic (1.28e-1)" "unprognostic (1.20e-2)" "unprognostic (1.79e-2)" "unprognostic (8.38e-2)" "unprognostic (1.73e-1)" "unprognostic (2.71e-1)" "unprognostic (1.97e-1)" "unprognostic (1.09e-1)" "unprognostic (3.38e-2)" UGCG GCS ENSG00000148154 "UDP-glucose ceramide glucosyltransferase" Q16739 9 111896814-111935369 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Lipid biosynthesis, Lipid metabolism, Sphingolipid metabolism" "Glycosyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 106.7" "Cell type enhanced" "Detected in all" "Endometrial glandular cells: 789.8;Esophageal apical cells: 1018.5;Neutrophil progenitors: 1446.9;pDCs: 984.0;Urothelial cells: 634.6" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 257.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 21 "plasmacytoid DC: 109.8" "Lineage enriched" "Detected in all" 21 "dendritic cells: 109.8" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Colon - Neutrophils, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024124 Approved NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 21: Non-specific - Metabolism" "Cluster 72: Neuronal - Signal transduction" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 2 "HPA024124: " "unprognostic (7.42e-3)" "unprognostic (2.98e-2)" "unprognostic (1.32e-1)" "unprognostic (5.61e-2)" "unprognostic (5.82e-2)" "unprognostic (7.20e-3)" "unprognostic (5.29e-3)" "potential prognostic unfavorable (2.77e-4)" "unprognostic (5.56e-2)" "unprognostic (1.80e-1)" "unprognostic (6.09e-2)" "unprognostic (5.48e-3)" "unprognostic (2.20e-1)" "unprognostic (6.47e-2)" "unprognostic (4.64e-2)" "unprognostic (3.01e-1)" "unprognostic (1.87e-1)" "unprognostic (3.48e-2)" "unprognostic (7.23e-2)" "unprognostic (8.55e-2)" "unprognostic (2.32e-1)" "unprognostic (2.02e-2)" "unprognostic (3.03e-2)" "unprognostic (1.93e-1)" "unprognostic (9.30e-2)" "unprognostic (1.31e-1)" "unprognostic (2.88e-1)" "unprognostic (3.85e-2)" "unprognostic (8.79e-2)" "unprognostic (3.20e-1)" "unprognostic (1.92e-1)" UGDH ENSG00000109814 "UDP-glucose 6-dehydrogenase" O60701 4 39498755-39528311 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism" "Allosteric enzyme, Oxidoreductase" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 128.7" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 439.4;Colonocytes: 642.3;Enterocytes: 401.9;Goblet cells: 300.8;Hepatocytes: 346.1;Pancreatic acinar cells: 404.0" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 98.9;oligodendrocyte precursor cell: 96.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034444, HPA036656, HPA036657" Enhanced Approved Nucleoplasm Yes No 830000 "Cluster 41: Basophils - Unknown function" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 7: Liver cancer - Metabolism" "Cluster 65: Non-specific - Cell growth & division" 4 Nucleoplasm "CAB034444: , HPA036656: , HPA036657: " "unprognostic (9.58e-3)" "unprognostic (1.23e-1)" "unprognostic (1.77e-2)" "unprognostic (5.64e-2)" "unprognostic (3.42e-2)" "unprognostic (7.25e-2)" "unprognostic (3.42e-1)" "unprognostic (1.13e-1)" "unprognostic (3.03e-2)" "unprognostic (1.16e-1)" "unprognostic (2.00e-3)" "unprognostic (6.12e-2)" "potential prognostic unfavorable (1.13e-5)" "unprognostic (1.43e-3)" "unprognostic (1.39e-2)" "unprognostic (5.48e-3)" "unprognostic (5.29e-3)" "unprognostic (4.71e-1)" "unprognostic (4.27e-2)" "unprognostic (4.16e-2)" "unprognostic (2.41e-1)" "unprognostic (1.24e-2)" "unprognostic (4.01e-1)" "unprognostic (5.05e-2)" "unprognostic (1.88e-1)" "unprognostic (2.72e-3)" "unprognostic (3.67e-1)" "unprognostic (2.58e-1)" "unprognostic (5.06e-2)" "unprognostic (4.43e-2)" "unprognostic (6.68e-2)" UGGT1 "HUGT1, UGCGL1" ENSG00000136731 "UDP-glucose glycoprotein glucosyltransferase 1" Q9NYU2 2 128091200-128195677 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 222.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012761, HPA015127" Enhanced Uncertain "Primary cilium,Primary cilium transition zone,Cytosol" "Intracellular and membrane" Enzyme NA NA 3400000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 63: Non-specific - Protein processing" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 14 Cytosol "Primary cilium, Primary cilium transition zone" "HPA012761: , HPA015127: " "unprognostic (2.48e-3)" "unprognostic (1.71e-2)" "unprognostic (1.22e-1)" "unprognostic (3.19e-3)" "unprognostic (6.79e-2)" "unprognostic (2.12e-1)" "unprognostic (1.07e-1)" "unprognostic (2.10e-1)" "unprognostic (6.77e-3)" "unprognostic (1.93e-2)" "unprognostic (3.01e-3)" "unprognostic (9.91e-2)" "unprognostic (4.52e-2)" "unprognostic (1.42e-3)" "unprognostic (2.02e-3)" "unprognostic (5.16e-3)" "unprognostic (1.04e-1)" "unprognostic (1.38e-1)" "unprognostic (1.14e-1)" "unprognostic (2.07e-1)" "unprognostic (1.18e-1)" "unprognostic (1.39e-2)" "unprognostic (2.21e-2)" "unprognostic (1.82e-1)" "unprognostic (9.14e-2)" "unprognostic (1.57e-1)" "unprognostic (1.68e-2)" "unprognostic (5.36e-2)" "unprognostic (1.17e-1)" "unprognostic (3.97e-2)" "unprognostic (2.15e-3)" UGGT2 "FLJ10873, FLJ11485, HUGT2, MGC117360, MGC150689, MGC87276, UGCGL2" ENSG00000102595 "UDP-glucose glycoprotein glucosyltransferase 2" Q9NYU1 13 95801580-96053482 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 5.9;eosinophil: 2.6;intermediate monocyte: 6.2;myeloid DC: 3.6;non-classical monocyte: 6.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA047955 Uncertain "Intracellular and membrane" Enzyme NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 9: Non-specific - Receptor signaling" "Cluster 19: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 19 "HPA047955: " "unprognostic (1.34e-2)" "unprognostic (2.26e-2)" "unprognostic (3.20e-2)" "unprognostic (1.93e-1)" "unprognostic (6.97e-2)" "unprognostic (2.51e-1)" "unprognostic (1.62e-1)" "potential prognostic favorable (4.09e-4)" "unprognostic (1.54e-2)" "unprognostic (1.77e-2)" "unprognostic (1.05e-3)" "unprognostic (2.34e-1)" "unprognostic (2.27e-1)" "unprognostic (1.60e-3)" "unprognostic (4.18e-2)" "unprognostic (1.32e-3)" "unprognostic (3.13e-3)" "unprognostic (1.75e-3)" "unprognostic (2.83e-1)" "unprognostic (6.67e-2)" "unprognostic (2.44e-1)" "unprognostic (2.07e-2)" "unprognostic (5.46e-3)" "unprognostic (1.72e-2)" "unprognostic (8.05e-2)" "unprognostic (3.74e-3)" "unprognostic (2.10e-2)" "unprognostic (7.63e-2)" "unprognostic (2.39e-1)" "unprognostic (1.56e-1)" "unprognostic (2.76e-1)" UGP2 "SVUGP2, UGP1, UGPP1" ENSG00000169764 "UDP-glucose pyrophosphorylase 2" Q16851 2 63840952-63891562 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 802.6;tongue: 706.3" "Cell type enriched" "Detected in all" 4 "Breast lactating cells: 3606.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 418.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Liver - Hepatocytes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034696, HPA034697, HPA064836" Enhanced Approved Nucleoplasm,Centrosome,Mitochondria NA NA 26000000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 4: Breast lactating luminal cells - Lactation" 7 "Centrosome, Mitochondria" Nucleoplasm "HPA034696: , HPA034697: , HPA064836: " "unprognostic (2.39e-2)" "unprognostic (4.41e-3)" "unprognostic (3.98e-1)" "unprognostic (6.67e-2)" "unprognostic (9.23e-2)" "unprognostic (2.46e-1)" "unprognostic (1.72e-2)" "unprognostic (2.02e-3)" "unprognostic (3.91e-2)" "unprognostic (6.94e-3)" "potential prognostic favorable (3.55e-4)" "unprognostic (1.08e-1)" "unprognostic (9.02e-2)" "validated prognostic favorable (7.41e-5)" "validated prognostic favorable (3.94e-5)" "unprognostic (2.22e-3)" "unprognostic (2.17e-2)" "unprognostic (4.07e-2)" "unprognostic (5.88e-2)" "unprognostic (4.10e-1)" "unprognostic (3.64e-2)" "unprognostic (1.41e-3)" "unprognostic (3.40e-2)" "unprognostic (8.34e-2)" "unprognostic (2.36e-1)" "unprognostic (5.77e-2)" "unprognostic (2.49e-1)" "potential prognostic unfavorable (9.80e-4)" "unprognostic (1.07e-1)" "unprognostic (9.39e-2)" "unprognostic (3.48e-3)" UGT1A1 "GNT1, UGT1, UGT1A" ENSG00000241635 "UDP glucuronosyltransferase family 1 member A1" P22309 2 233760270-233773300 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 28 "intestine: 189.0;liver: 344.8" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 16 "Liver Hepatocellular Carcinoma (TCGA): 167.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.4" "Cancer enhanced" "Detected in many" "liver cancer: 47.3" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 9: Non-specific - Receptor signaling" "Cluster 7: Liver cancer - Metabolism" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 8 "unprognostic (7.36e-3)" "unprognostic (6.14e-2)" "unprognostic (5.55e-2)" "unprognostic (8.42e-2)" "unprognostic (2.11e-1)" "unprognostic (1.93e-2)" "unprognostic (1.98e-2)" "potential prognostic unfavorable (1.15e-7)" "unprognostic (7.26e-2)" "unprognostic (3.66e-1)" "unprognostic (1.72e-1)" "unprognostic (3.67e-3)" "unprognostic (4.67e-2)" "unprognostic (1.38e-2)" "unprognostic (1.07e-2)" "unprognostic (1.35e-1)" "unprognostic (4.78e-3)" "unprognostic (1.74e-1)" "unprognostic (1.73e-1)" "unprognostic (5.12e-2)" "unprognostic (4.04e-2)" UGT1A10 UGT1J ENSG00000242515 "UDP glucuronosyltransferase family 1 member A10" Q9HAW8 2 233636448-233773300 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "gallbladder: 20.7;intestine: 74.5;stomach 1: 30.9" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 85.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 81.8;Gallbladder cancer: 131.7;pancreatic cancer: 71.6" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Stomach - Gastric mucous cells" "Intracellular and membrane" Enzyme NA NA "Cluster 77: Intestine - Digestion" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 68: Foveolar cells - Mucosal defense" 1 "unprognostic (1.44e-1)" "unprognostic (5.46e-1)" "unprognostic (3.01e-2)" "unprognostic (2.37e-1)" "unprognostic (4.84e-2)" "validated prognostic unfavorable (7.49e-6)" "validated prognostic unfavorable (1.99e-8)" "potential prognostic unfavorable (6.97e-4)" "unprognostic (2.73e-3)" "unprognostic (4.56e-1)" "unprognostic (4.33e-1)" "unprognostic (1.03e-2)" "unprognostic (1.79e-3)" "unprognostic (1.67e-1)" "potential prognostic unfavorable (7.11e-4)" "unprognostic (1.80e-1)" "unprognostic (5.14e-2)" "potential prognostic unfavorable (9.67e-4)" "unprognostic (3.33e-1)" "unprognostic (4.80e-2)" UGT1A3 UGT1C ENSG00000288702 "UDP glucuronosyltransferase family 1 member A3" P35503 2 233729042-233773300 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "liver: 63.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 3.4" "Liver - Hepatocytes" NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 7: Liver cancer - Metabolism" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 1 UGT1A4 "HUG-BR2, UGT1D" ENSG00000244474 "UDP glucuronosyltransferase family 1 member A4" P22310 2 233718736-233773300 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 68 "liver: 367.8" "Group enriched" "Detected in some" 4 "Early spermatids: 1.2;Late spermatids: 4.1" "Cancer enriched" "Detected in single" 681 "Liver Hepatocellular Carcinoma (TCGA): 155.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes" NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 32: Non-specific - Cell proliferation" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 1 "unprognostic (3.67e-2)" "unprognostic (3.22e-1)" "unprognostic (1.83e-1)" UGT1A5 UGT1E ENSG00000288705 "UDP glucuronosyltransferase family 1 member A5" P35504 2 233712907-233773300 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "gallbladder: 2.5;intestine: 8.3;liver: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 32: Non-specific - Cell proliferation" UGT1A6 "GNT1, HLUGP, UGT1F" ENSG00000167165 "UDP glucuronosyltransferase family 1 member A6" P19224 2 233691607-233773300 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "kidney: 66.4;liver: 134.2;urinary bladder: 83.3" "Cell type enhanced" "Detected in some" "Respiratory basal cells: 1.4;Salivary duct cells: 1.1;Urothelial cells: 2.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 124.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 261.8" "Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary gland basal cells, Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "CAB009819, HPA054065, HPA056023" Enhanced Supported "Endoplasmic reticulum,Vesicles" NA NA "Cluster 16: Liver & Kidney - Metabolism" "Cluster 7: Liver cancer - Metabolism" "Cluster 69: Urothelial cells - Basic cellular functions" 1 Vesicles "Endoplasmic reticulum" "CAB009819: , HPA054065: , HPA056023: " "unprognostic (7.66e-2)" "unprognostic (1.00e-1)" "potential prognostic favorable (2.79e-4)" "unprognostic (3.75e-3)" "unprognostic (1.05e-2)" "unprognostic (5.11e-2)" "unprognostic (1.29e-1)" "unprognostic (4.07e-3)" "unprognostic (3.92e-3)" "potential prognostic unfavorable (5.02e-4)" "potential prognostic unfavorable (3.08e-8)" "unprognostic (3.35e-1)" "unprognostic (3.60e-1)" "unprognostic (2.76e-2)" "unprognostic (4.50e-3)" "unprognostic (9.10e-2)" "unprognostic (1.75e-3)" "unprognostic (3.36e-1)" "unprognostic (4.52e-2)" "unprognostic (1.93e-1)" "unprognostic (3.04e-1)" "unprognostic (1.83e-1)" UGT1A7 UGT1G ENSG00000244122 "UDP glucuronosyltransferase family 1 member A7" Q9HAW7 2 233681901-233773300 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "esophagus: 78.7" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 16.9;Head and Neck Squamous Cell Carcinoma (TCGA): 22.6;Lung Squamous Cell Carcinoma (TCGA): 54.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 10.5;Esophageal cancer: 6.6;Kidney cancer: 6.8" "Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells" NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 48: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" 29 "unprognostic (1.40e-1)" "unprognostic (5.05e-2)" "unprognostic (8.36e-2)" "unprognostic (2.71e-1)" "unprognostic (2.80e-2)" "unprognostic (2.21e-1)" "unprognostic (7.96e-3)" "unprognostic (4.31e-2)" "unprognostic (9.66e-2)" "unprognostic (7.90e-2)" UGT1A8 UGT1H ENSG00000242366 "UDP glucuronosyltransferase family 1 member A8" Q9HAW9 2 233617633-233773300 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "gallbladder: 6.1;intestine: 14.9;urinary bladder: 28.0" "Group enriched" "Detected in some" 5 "Papillary tip epithelial cells: 5.7;Prostatic hillock cells: 13.0;Urothelial cells: 19.1" "Cancer enriched" "Detected in many" 4 "Bladder Urothelial Carcinoma (TCGA): 22.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Bile duct cancer: 8.9;Bladder cancer: 19.8;colorectal cancer: 8.2" "Colon - Colon enterocytes, Prostate - Urothelial cells" NA NA "Cluster 17: Intestine - Digestion" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 69: Urothelial cells - Basic cellular functions" 1 "unprognostic (8.15e-2)" "unprognostic (1.28e-1)" "unprognostic (3.14e-1)" "unprognostic (1.39e-1)" "validated prognostic unfavorable (2.27e-5)" "validated prognostic unfavorable (9.87e-6)" "potential prognostic unfavorable (8.27e-5)" "unprognostic (6.32e-2)" "unprognostic (2.05e-1)" "unprognostic (1.10e-1)" "unprognostic (3.67e-1)" "unprognostic (9.73e-2)" "unprognostic (1.86e-2)" UGT1A9 "HLUGP4, LUGP4, UGT1AI" ENSG00000241119 "UDP glucuronosyltransferase family 1 member A9" O60656 2 233671898-233773300 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 341 "kidney: 428.4;liver: 183.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 80 "Kidney Renal Clear Cell Carcinoma (TCGA): 122.8;Kidney Renal Papillary Cell Carcinoma (TCGA): 43.6;Liver Hepatocellular Carcinoma (TCGA): 96.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Kidney cancer: 109.6" "Kidney - Proximal tubular cells, Liver - Hepatocytes" NA NA "Cluster 76: Non-specific - Metabolism" "Cluster 15: Kidney cancer - Membrane components" 2 "unprognostic (3.19e-1)" "unprognostic (2.35e-3)" "unprognostic (3.35e-2)" "potential prognostic unfavorable (7.29e-5)" "unprognostic (5.53e-3)" "unprognostic (2.77e-1)" "unprognostic (1.39e-1)" UGT2A1 ENSG00000173610 "UDP glucuronosyltransferase family 2 member A1 complex locus" P0DTE4 4 69588417-69653249 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Olfaction, Sensory transduction" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 6.4;pituitary gland: 3.9" "Cell type enhanced" "Detected in some" "Conjunctival goblet cells: 19.4;Gonadotrophs: 116.1;Respiratory basal cells: 21.0;Respiratory deuterosomal cells: 11.4;Respiratory secretory cells: 30.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Lung Squamous Cell Carcinoma (TCGA): 4.8" "Region enriched" "Detected in single" 15 "choroid plexus: 7.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "lung cancer: 1.0;Myeloma: 1.4" "Pituitary gland - Gonadotropes, Skin - Sebaceous gland cells" "Not detected" "Not detected" "HPA017261, HPA045108" Uncertain NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" "HPA017261: , HPA045108: " "potential prognostic favorable (4.09e-4)" "unprognostic (3.17e-2)" "unprognostic (8.86e-2)" "unprognostic (4.84e-2)" UGT2A2 ENSG00000271271 "UDP glucuronosyltransferase family 2 member A2" P0DTE5 4 69588417-69639642 "Enzymes, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "kidney: 5.8;liver: 9.2" "Group enriched" "Detected in some" 7 "Choroid plexus epithelial cells: 2.2;Respiratory deuterosomal cells: 1.0" "Cell type enriched" "Detected in single" 39 "choroid plexus epithelial cell: 7.4" "Not detected" "Not detected" "Region enriched" "Detected in single" 16 "choroid plexus: 1.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045108 Uncertain NA NA "Cluster 16: Liver & Kidney - Metabolism" "Cluster 36: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 101: Choroid plexus epithelial cells - Ion transport" "HPA045108: " "unprognostic (2.10e-2)" "unprognostic (2.04e-1)" UGT2A3 FLJ21934 ENSG00000135220 "UDP glucuronosyltransferase family 2 member A3" Q6UWM9 4 68928463-68951804 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "intestine: 29.6;kidney: 19.9;liver: 12.5;pancreas: 14.8" "Cell type enriched" "Detected in some" 7 "Proximal tubule cells: 108.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney Renal Clear Cell Carcinoma (TCGA): 1.5;Kidney Renal Papillary Cell Carcinoma (TCGA): 1.2;Stomach Adenocarcinoma (TCGA): 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enterocytes, Kidney - Proximal tubular cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA045108 Supported NA NA "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 18: Liver cancer - Metabolism" "Cluster 88: Proximal tubular cells - Transmembrane transport" "HPA045108: " "unprognostic (1.94e-1)" "potential prognostic favorable (1.40e-8)" "unprognostic (2.24e-2)" "unprognostic (2.43e-3)" "unprognostic (1.30e-1)" "unprognostic (2.40e-2)" "unprognostic (1.58e-1)" UGT2B10 ENSG00000109181 "UDP glucuronosyltransferase family 2 member B10" P36537 4 68815994-68832023 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 148 "liver: 218.6" "Cell type enriched" "Detected in some" 4 "Hepatocytes: 14.2" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 132 "Liver Hepatocellular Carcinoma (TCGA): 40.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "liver cancer: 2.1" "Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" HPA045108 Uncertain NA NA "Cluster 53: Liver - Plasma proteins" "Cluster 18: Liver cancer - Metabolism" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" "HPA045108: " "unprognostic (5.90e-3)" "potential prognostic favorable (1.89e-4)" UGT2B11 ENSG00000213759 "UDP glucuronosyltransferase family 2 member B11" O75310 4 69199951-69214748 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "breast: 225.4" "Group enriched" "Detected in some" 5 "Breast hormone-responsive cells: 24.4;Salivary acinar cells: 22.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 16 "Breast Invasive Carcinoma (TCGA): 36.8;Liver Hepatocellular Carcinoma (TCGA): 22.5" "Not detected" "Not detected" "Group enriched" "Detected in some" 42 "basophil: 4.7;eosinophil: 3.6" "Lineage enriched" "Detected in single" 48 "granulocytes: 4.7" "Group enriched" "Detected in some" 14 "liver cancer: 6.5;prostate cancer: 16.3" "Liver - Hepatocytes" HPA045108 Uncertain NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 55: Breast - Lactation" "Cluster 60: Prostate cancer - Unknown function" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 1 "HPA045108: " "unprognostic (2.60e-1)" "unprognostic (4.59e-1)" "potential prognostic favorable (5.36e-7)" "unprognostic (1.98e-1)" "unprognostic (7.25e-3)" "potential prognostic unfavorable (1.78e-4)" "unprognostic (5.23e-2)" "unprognostic (2.83e-2)" "unprognostic (5.90e-2)" "unprognostic (5.31e-2)" UGT2B15 UGT2B8 ENSG00000196620 "UDP glucuronosyltransferase family 2 member B15" P54855 4 68646597-68670652 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "gallbladder: 73.0;liver: 272.2" "Cell type enhanced" "Detected in some" "Cholangiocytes: 57.9;Foveolar cells: 12.5;Gastric chief cells: 29.5;Hepatocytes: 43.9;Mucous neck cells: 9.1;Parietal cells: 17.7" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "Liver Hepatocellular Carcinoma (TCGA): 78.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 8 "prostate cancer: 9.8" "Breast - Breast glandular cells, Colon - Colon enterocytes, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells" HPA045108 Uncertain NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 60: Prostate cancer - Unknown function" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" "HPA045108: " "unprognostic (2.39e-1)" "unprognostic (9.46e-2)" "unprognostic (2.37e-1)" "unprognostic (1.62e-2)" "unprognostic (1.05e-3)" "unprognostic (1.71e-2)" "potential prognostic favorable (2.28e-4)" "unprognostic (1.63e-1)" "unprognostic (2.04e-1)" "unprognostic (6.26e-2)" "unprognostic (7.71e-2)" "unprognostic (2.76e-1)" "unprognostic (5.57e-2)" "unprognostic (1.40e-2)" UGT2B17 ENSG00000197888 "UDP glucuronosyltransferase family 2 member B17" O75795 4 68537173-68576413 "Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "intestine: 357.0;liver: 104.0" "Group enriched" "Detected in some" 5 "Colonocytes: 150.6;Endometrial secretory cells: 45.1;Enteric stem cells: 140.4;Enteric transient amplifying cells: 157.2" "Not detected" "Not detected" "Group enriched" "Detected in many" 8 "Colon Adenocarcinoma (TCGA): 28.9;Liver Hepatocellular Carcinoma (TCGA): 18.7;Rectum Adenocarcinoma (TCGA): 29.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 39 "memory B-cell: 4.0;naive B-cell: 15.2" "Lineage enriched" "Detected in single" 61 "B-cells: 15.2" "Group enriched" "Detected in some" 4 "lymphoma: 5.2;Myeloma: 7.1;prostate cancer: 12.6" "Colon - Colon enterocytes, Minor Salivary Gland - Plasma cells" HPA045108 Supported NA NA "Cluster 34: B-cells - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 55: Lymphoma - Immune response" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" "HPA045108: " "unprognostic (1.93e-1)" "unprognostic (7.25e-3)" "unprognostic (1.22e-1)" "unprognostic (2.85e-1)" "unprognostic (1.74e-1)" "unprognostic (5.47e-2)" "unprognostic (7.98e-2)" "unprognostic (3.98e-2)" "unprognostic (3.55e-1)" "unprognostic (2.50e-2)" "unprognostic (8.56e-2)" "unprognostic (3.51e-1)" "unprognostic (4.37e-3)" "unprognostic (1.12e-1)" "unprognostic (3.12e-1)" "unprognostic (5.15e-3)" UGT2B28 ENSG00000135226 "UDP glucuronosyltransferase family 2 member B28" Q9BY64 4 69280475-69295050 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "breast: 186.9" "Group enriched" "Detected in some" 13 "Cholangiocytes: 10.8;Salivary acinar cells: 27.3" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Breast Invasive Carcinoma (TCGA): 4.8" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "eosinophil: 1.3" "Lineage enriched" "Detected in single" 13 "granulocytes: 1.3" "Cancer enriched" "Detected in single" 9 "prostate cancer: 4.1" "Minor Salivary Gland - Minor salivary glandular cells" HPA045108 Uncertain "Intracellular and membrane" Enzyme NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 55: Breast - Lactation" "Cluster 60: Prostate cancer - Unknown function" "Cluster 38: Secretory epithelial cells - Exocrine secretion" "HPA045108: " "unprognostic (1.04e-1)" "unprognostic (1.83e-1)" "unprognostic (1.73e-3)" UGT2B4 UGT2B11 ENSG00000156096 "UDP glucuronosyltransferase family 2 member B4" P06133 4 69480165-69526014 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 106 "liver: 1190.8" "Cell type enriched" "Detected in some" 9 "Hepatocytes: 1054.5" "Cell type enriched" "Detected in single" 66 "midbrain-derived inhibitory: 11.9" "Cancer enriched" "Detected in some" 67 "Liver Hepatocellular Carcinoma (TCGA): 530.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 17 "liver cancer: 32.2" "Liver - Hepatocytes" "CAB033260, HPA045108" Enhanced "Intracellular and membrane" Enzyme NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 7: Liver cancer - Metabolism" "Cluster 93: Hepatocytes - Bile production & excretion" "CAB033260: , HPA045108: " "unprognostic (5.83e-2)" "unprognostic (2.98e-1)" "unprognostic (1.92e-1)" "unprognostic (2.52e-2)" "unprognostic (1.70e-2)" "unprognostic (3.77e-3)" "unprognostic (5.30e-2)" UGT2B7 UGT2B9 ENSG00000171234 "UDP glucuronosyltransferase family 2 member B7" P16662 4 69051363-69112987 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 21 "kidney: 1212.8;liver: 1507.2" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 370.8;Endometrial glandular cells: 1022.8;Endometrial luminal cells: 1392.9;Endometrial secretory cells: 297.9;Epididymal basal cells: 243.7;Epididymal efferent duct absorptive cells: 618.6;Fallopian secretory cells: 406.9;Hepatocytes: 732.9;Loop of henle epithelial cells: 449.5;Papillary tip epithelial cells: 255.7;Proximal tubule cells: 555.6;Renal collecting duct principal cells: 206.4" "Cell type enriched" "Detected in single" 5 "committed oligodendrocyte precursor: 2.0" "Group enriched" "Detected in many" 5 "Kidney Renal Clear Cell Carcinoma (TCGA): 258.9;Kidney Renal Papillary Cell Carcinoma (TCGA): 254.1;Liver Hepatocellular Carcinoma (TCGA): 177.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 86.1;Uterine cancer: 39.8" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" HPA045108 Uncertain NA NA "Cluster 16: Liver & Kidney - Metabolism" "Cluster 15: Kidney cancer - Membrane components" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 1 "HPA045108: " "unprognostic (3.81e-1)" "unprognostic (1.80e-1)" "unprognostic (1.57e-1)" "potential prognostic favorable (3.08e-5)" "unprognostic (8.94e-2)" "unprognostic (7.39e-2)" "validated prognostic favorable (4.07e-10)" "validated prognostic favorable (9.93e-4)" "unprognostic (2.90e-2)" "unprognostic (8.17e-2)" "unprognostic (1.22e-2)" "unprognostic (6.67e-3)" "unprognostic (1.09e-1)" "unprognostic (4.61e-2)" "unprognostic (4.08e-2)" "unprognostic (5.53e-2)" "unprognostic (1.66e-1)" "potential prognostic unfavorable (5.27e-4)" "unprognostic (1.52e-1)" "unprognostic (6.91e-2)" "unprognostic (1.08e-1)" "unprognostic (7.81e-2)" "unprognostic (1.29e-2)" "unprognostic (2.92e-1)" "unprognostic (4.81e-1)" UGT3A1 FLJ34658 ENSG00000145626 "UDP glycosyltransferase family 3 member A1" Q6NUS8 5 35951006-36001028 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "kidney: 47.6;liver: 54.2" "Cell type enhanced" "Detected in some" "Early spermatids: 122.6;Gonadotrophs: 21.0;Hepatocytes: 86.6;Late primary spermatocytes: 111.8;Late spermatids: 26.0;Myonuclei: 19.4;Proximal tubule cells: 48.7;Renal collecting duct principal cells: 36.0;Renal connecting tubule cells: 17.8" "Cell type enhanced" "Detected in single" "lower rhombic lip: 1.6" "Group enriched" "Detected in some" 9 "Kidney Renal Clear Cell Carcinoma (TCGA): 11.5;Kidney Renal Papillary Cell Carcinoma (TCGA): 9.5;Liver Hepatocellular Carcinoma (TCGA): 12.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Kidney cancer: 2.5;Sarcoma: 1.4" "Kidney - Proximal tubular cells, Pituitary gland - Gonadotropes, Skin - Inner root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "HPA047697, HPA056290" Uncertain Approved Vesicles,Cytosol NA NA "Cluster 16: Liver & Kidney - Metabolism" "Cluster 9: Non-specific - Receptor signaling" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" 1 "Vesicles, Cytosol" "HPA047697: , HPA056290: " "potential prognostic favorable (1.03e-5)" "unprognostic (1.65e-3)" "potential prognostic unfavorable (3.94e-5)" "unprognostic (2.18e-1)" "potential prognostic favorable (2.58e-4)" "unprognostic (2.93e-1)" UGT3A2 ENSG00000168671 "UDP glycosyltransferase family 3 member A2" Q3SY77 5 36035021-36071358 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.1;lymphoid tissue: 13.6;skin 1: 9.7" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 10.6;Early spermatids: 3.7;Late spermatids: 14.7;Neutrophil progenitors: 2.7;Retinal ganglion cells: 3.9;Retinal pigment epithelial cells: 12.8;Sertoli cells: 5.6;Thymocytes: 7.6;Thyrotrophs: 7.3" "Cell type enhanced" "Detected in some" "cerebellar inhibitory: 1.7;lower rhombic lip: 2.8;thalamic excitatory: 2.2" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 7.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "Bone cancer: 178.0" "Colon - Colon enteroendocrine cells, Kidney - Proximal tubular cells, Pituitary gland - Thyrotropes" "Not detected" "Not detected" HPA059475 Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" Yes NA "Cluster 49: Non-specific - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" Nucleoplasm "Golgi apparatus, Cytosol" "HPA059475: " "unprognostic (1.15e-2)" "unprognostic (6.56e-2)" "unprognostic (4.16e-3)" "unprognostic (1.94e-1)" "unprognostic (7.12e-3)" "unprognostic (2.06e-1)" UGT8 CGT ENSG00000174607 "UDP glycosyltransferase 8" Q16880 4 114598770-114678225 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 244.3" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 88.1;Loop of henle epithelial cells: 243.3;Oligodendrocyte progenitor cells: 135.4;Oligodendrocytes: 850.8;Renal collecting duct intercalated cells: 300.3;Tuft cells: 92.2" "Group enriched" "Detected in many" 5 "committed oligodendrocyte precursor: 526.4;oligodendrocyte: 1203.7" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 70.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "memory B-cell: 6.9;naive B-cell: 10.7" "Lineage enriched" "Detected in single" 13 "B-cells: 10.7" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Skin - Eccrine sweat gland cells, Spleen - B-cells (Spleen), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014405, HPA065785" Enhanced Approved Mitochondria No No "Cluster 14: Non-specific - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 11: Neuronal - Sensory perception" "Cluster 80: Oligodendrocytes - Myelination" 24 Mitochondria "HPA014405: , HPA065785: " "unprognostic (3.52e-1)" "unprognostic (2.01e-1)" "unprognostic (3.65e-1)" "unprognostic (2.91e-2)" "unprognostic (1.71e-2)" "unprognostic (1.70e-1)" "unprognostic (2.13e-1)" "potential prognostic favorable (7.11e-4)" "unprognostic (4.10e-2)" "unprognostic (3.02e-2)" "potential prognostic favorable (1.68e-5)" "unprognostic (2.20e-2)" "unprognostic (2.43e-1)" "unprognostic (1.36e-1)" "unprognostic (1.22e-1)" "unprognostic (1.44e-1)" "unprognostic (1.16e-1)" "unprognostic (2.27e-1)" "unprognostic (1.10e-2)" "unprognostic (4.28e-1)" "unprognostic (4.18e-2)" "unprognostic (1.71e-1)" "unprognostic (1.91e-1)" "unprognostic (1.90e-1)" "unprognostic (7.58e-2)" "unprognostic (2.09e-1)" "unprognostic (8.49e-2)" "unprognostic (8.29e-2)" "unprognostic (4.03e-2)" "unprognostic (8.45e-2)" UHMK1 "KIS, Kist" ENSG00000152332 "U2AF homology motif kinase 1" Q8TAS1 1 162497251-162529631 "Enzymes, Predicted intracellular proteins" "Kinase, RNA-binding, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031056 Supported Nucleoplasm NA No "Cluster 33: Non-specific - ATP binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 45: Non-specific - Nuclear processes" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 1 Nucleoplasm "HPA031056: " "unprognostic (9.61e-2)" "unprognostic (3.68e-2)" "unprognostic (1.95e-3)" "unprognostic (1.00e-1)" "unprognostic (3.91e-2)" "unprognostic (8.48e-2)" "unprognostic (3.51e-1)" "unprognostic (2.47e-2)" "unprognostic (6.01e-2)" "unprognostic (1.46e-2)" "potential prognostic favorable (3.81e-5)" "unprognostic (2.12e-1)" "unprognostic (5.00e-2)" "unprognostic (6.64e-2)" "unprognostic (1.50e-1)" "unprognostic (4.03e-3)" "unprognostic (2.55e-2)" "unprognostic (7.74e-2)" "unprognostic (2.99e-1)" "unprognostic (2.15e-1)" "unprognostic (1.88e-3)" "unprognostic (1.25e-2)" "unprognostic (4.56e-1)" "unprognostic (7.91e-2)" "unprognostic (3.94e-2)" "unprognostic (1.39e-2)" "unprognostic (8.65e-2)" "unprognostic (3.83e-2)" "unprognostic (2.87e-1)" "unprognostic (6.43e-3)" "unprognostic (8.16e-2)" UHRF1 "FLJ21925, ICBP90, Np95, RNF106, TDRD22" ENSG00000276043 "Ubiquitin like with PHD and ring finger domains 1" Q96T88 19 4903080-4962154 "Disease related genes, Enzymes, Essential proteins, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair, Transcription, Transcription regulation, Ubl conjugation pathway" "Chromatin regulator, DNA-binding, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "bone marrow: 25.5;lymphoid tissue: 62.6" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 24.4;Erythrocyte progenitors: 57.7;Gastric progenitor cells: 28.2;Megakaryocyte progenitors: 24.5;Monocyte progenitors: 77.1;Neutrophil progenitors: 40.5;Thymocytes: 26.3" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 11.1;ependymal cell: 8.3;leukocyte: 11.3;oligodendrocyte precursor cell: 8.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 4.8" "Group enriched" "Detected in many" 4 "dendritic cells: 4.8;T-cells: 2.3" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA049408, HPA055446" Enhanced Supported Nucleoplasm No Yes "Cluster 13: Non-specific - Mitochondria" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 11: White matter - Signal transduction" "Cluster 6: Leukemia - Signal transduction" "Cluster 27: Non-specific - Cell proliferation" 71 Nucleoplasm "HPA049408: , HPA055446: " "unprognostic (1.32e-1)" "unprognostic (3.84e-2)" "unprognostic (1.88e-1)" "unprognostic (1.01e-1)" "unprognostic (6.58e-2)" "unprognostic (3.81e-1)" "unprognostic (2.00e-1)" "unprognostic (1.03e-2)" "unprognostic (3.97e-3)" "validated prognostic unfavorable (1.02e-6)" "validated prognostic unfavorable (1.80e-4)" "potential prognostic unfavorable (1.83e-7)" "validated prognostic unfavorable (1.14e-4)" "validated prognostic unfavorable (9.65e-5)" "potential prognostic unfavorable (3.36e-4)" "unprognostic (1.69e-3)" "unprognostic (3.86e-2)" "unprognostic (1.36e-1)" "unprognostic (2.60e-1)" "potential prognostic unfavorable (1.08e-5)" "unprognostic (4.63e-3)" "unprognostic (2.06e-1)" "unprognostic (7.63e-3)" "potential prognostic unfavorable (2.26e-4)" "unprognostic (2.66e-3)" "unprognostic (2.68e-1)" "unprognostic (1.46e-1)" "unprognostic (6.36e-2)" UHRF2 "MGC33463, NIRF, RNF107, TDRD23, URF2" ENSG00000147854 "Ubiquitin like with PHD and ring finger domains 2" Q96PU4 9 6413151-6507054 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Ubl conjugation pathway" "DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 376.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026633, HPA026697" Enhanced Nucleoplasm,Vesicles NA NA "Cluster 32: Basophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 41 Nucleoplasm Vesicles "HPA026633: , HPA026697: " "unprognostic (3.62e-1)" "unprognostic (1.41e-1)" "unprognostic (1.31e-1)" "unprognostic (3.46e-1)" "unprognostic (5.25e-3)" "unprognostic (8.83e-2)" "unprognostic (1.32e-1)" "unprognostic (1.55e-2)" "unprognostic (6.21e-2)" "unprognostic (3.10e-1)" "potential prognostic favorable (9.44e-7)" "unprognostic (3.88e-3)" "unprognostic (9.86e-2)" "unprognostic (2.97e-3)" "unprognostic (2.91e-1)" "unprognostic (8.86e-2)" "potential prognostic unfavorable (1.93e-4)" "unprognostic (1.75e-1)" "unprognostic (8.77e-2)" "unprognostic (3.66e-1)" "unprognostic (5.60e-2)" "unprognostic (2.34e-2)" "potential prognostic unfavorable (1.33e-5)" "unprognostic (9.97e-2)" "unprognostic (4.04e-3)" "unprognostic (4.92e-2)" "unprognostic (1.74e-1)" "unprognostic (7.67e-2)" "unprognostic (1.98e-1)" "unprognostic (9.69e-2)" "unprognostic (5.86e-2)" UIMC1 RAP80 ENSG00000087206 "Ubiquitin interaction motif containing 1" Q96RL1 5 176905005-177022633 "Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 410.7;Platelets: 311.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 65.0" "Lineage enriched" "Detected in all" 4 "granulocytes: 65.0" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037503, HPA037504" Enhanced Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 15: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 24: Neutrophils - Innate immunity signal integration" 29 "Nuclear bodies" Nucleoplasm "HPA037503: , HPA037504: " "unprognostic (2.00e-2)" "unprognostic (1.44e-1)" "unprognostic (1.87e-1)" "unprognostic (3.28e-1)" "unprognostic (1.95e-1)" "unprognostic (7.51e-2)" "unprognostic (7.28e-2)" "unprognostic (2.32e-2)" "potential prognostic unfavorable (1.03e-4)" "potential prognostic unfavorable (5.37e-5)" "unprognostic (1.75e-2)" "unprognostic (2.12e-3)" "unprognostic (2.38e-1)" "potential prognostic unfavorable (1.24e-4)" "unprognostic (5.09e-3)" "unprognostic (8.89e-3)" "unprognostic (4.86e-2)" "unprognostic (8.08e-2)" "unprognostic (1.02e-1)" "unprognostic (6.26e-2)" "unprognostic (1.46e-1)" "unprognostic (2.43e-2)" "unprognostic (5.46e-3)" "unprognostic (3.56e-3)" "unprognostic (5.92e-2)" "unprognostic (9.29e-2)" "unprognostic (2.58e-3)" "unprognostic (2.03e-1)" "unprognostic (1.64e-1)" "unprognostic (8.62e-2)" "unprognostic (6.24e-2)" ULBP1 RAET1I ENSG00000111981 "UL16 binding protein 1" Q9BZM6 6 149963943-149973715 "Predicted membrane proteins" "Host-virus interaction, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 3.6;lung: 1.5;testis: 3.2" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 1.7;Breast secretory cells: 1.9;cDC: 3.3;Epididymal basal cells: 4.2;Esophageal apical cells: 2.9;Esophageal suprabasal cells: 2.6;Ocular epithelial cells: 15.7" "Cell type enhanced" "Detected in some" "hippocampal CA4: 2.7;hippocampal dentate gyrus: 1.7;upper rhombic lip: 1.1" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "cerebellum: 10.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "HPA007547, HPA071005" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 13: Non-specific - Mixed function" "Cluster 100: Stratified epithelial cells - Barrier functions" 3 "Plasma membrane, Cytosol" "HPA007547: , HPA071005: " "unprognostic (8.66e-2)" "unprognostic (3.00e-1)" "unprognostic (2.30e-3)" "unprognostic (3.34e-3)" "potential prognostic unfavorable (8.05e-4)" "unprognostic (1.90e-2)" "unprognostic (7.41e-2)" "unprognostic (6.32e-2)" "unprognostic (6.13e-2)" "unprognostic (4.75e-2)" "unprognostic (9.47e-2)" "unprognostic (5.01e-2)" "unprognostic (1.11e-1)" ULBP2 RAET1H ENSG00000131015 "UL16 binding protein 2" Q9BZM5 6 149942014-149949235 "Predicted membrane proteins, Predicted secreted proteins" "Host-virus interaction, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 5.9" "Cell type enhanced" "Detected in some" "Early primary spermatocytes: 7.9;Early spermatids: 7.5;Epididymal basal cells: 10.2;Esophageal apical cells: 15.5;Esophageal suprabasal cells: 15.3;Late spermatids: 13.3;NK-cells: 6.5;Ocular epithelial cells: 44.2;Pancreatic acinar cells: 13.1;T-cells: 9.0" "Cell type enhanced" "Detected in many" "lower rhombic lip: 7.5" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 22.6" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.7" "Lineage enriched" "Detected in single" 6 "T-cells: 2.7" "Low cancer specificity" "Detected in many" "Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells" "CAB018974, HPA066741" Approved Supported "Vesicles,Plasma membrane" "Secreted in other tissues" Immunity NA NA "Cluster 1: T-cells - Unknown function" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 5 "Vesicles, Plasma membrane" "CAB018974: , HPA066741: " "unprognostic (4.46e-2)" "potential prognostic unfavorable (1.75e-5)" "unprognostic (4.82e-3)" "unprognostic (5.29e-2)" "unprognostic (1.75e-3)" "unprognostic (1.59e-1)" "potential prognostic unfavorable (4.93e-4)" "unprognostic (6.34e-2)" "unprognostic (1.53e-3)" "unprognostic (4.64e-2)" "unprognostic (1.36e-2)" "unprognostic (1.57e-1)" "unprognostic (1.15e-1)" "unprognostic (4.56e-2)" "unprognostic (5.59e-2)" "unprognostic (2.88e-1)" "unprognostic (6.36e-2)" "unprognostic (2.67e-1)" "potential prognostic unfavorable (1.51e-4)" "unprognostic (8.69e-2)" "unprognostic (8.50e-2)" "unprognostic (1.17e-1)" "unprognostic (1.10e-1)" "unprognostic (1.57e-1)" "unprognostic (1.85e-1)" "unprognostic (3.32e-1)" "unprognostic (5.67e-2)" ULBP3 RAET1N ENSG00000131019 "UL16 binding protein 3" Q9BZM4 6 150061053-150069121 "Predicted intracellular proteins" "Host-virus interaction, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 6.1;testis: 5.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 6.6;Endometrial secretory cells: 9.7;Epididymal basal cells: 6.2;Esophageal suprabasal cells: 5.6;Gastric progenitor cells: 5.1;Hepatic stellate cells: 6.5;Ocular epithelial cells: 13.9;Tuft cells: 11.5" "Cell type enhanced" "Detected in many" "hippocampal CA4: 5.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "HPA056541, HPA063007, HPA069810" Approved Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" Immunity NA NA "Cluster 1: T-cells - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 9: Non-specific - Receptor signaling" "Cluster 32: Non-specific - Cell proliferation" "Cluster 100: Stratified epithelial cells - Barrier functions" 12 Vesicles "Golgi apparatus" "HPA056541: , HPA063007: , HPA069810: " "unprognostic (2.28e-2)" "unprognostic (8.74e-2)" "unprognostic (3.65e-2)" "unprognostic (8.92e-2)" "unprognostic (1.60e-2)" "unprognostic (4.87e-2)" "unprognostic (1.64e-1)" "potential prognostic unfavorable (2.37e-4)" "unprognostic (2.89e-2)" "unprognostic (6.76e-2)" "unprognostic (1.07e-3)" "unprognostic (2.56e-1)" "potential prognostic favorable (3.82e-4)" "unprognostic (4.38e-2)" "unprognostic (5.02e-2)" "unprognostic (1.36e-1)" "unprognostic (1.32e-1)" "unprognostic (2.56e-2)" "potential prognostic unfavorable (2.10e-4)" "unprognostic (7.95e-2)" "unprognostic (2.21e-2)" "unprognostic (1.59e-1)" "unprognostic (1.43e-2)" "unprognostic (5.62e-2)" "unprognostic (1.55e-1)" "unprognostic (2.38e-1)" "unprognostic (2.07e-2)" "unprognostic (1.52e-1)" ULK1 "ATG1, ATG1A" ENSG00000177169 "Unc-51 like autophagy activating kinase 1" O75385 12 131894622-131923150 "Enzymes, Plasma proteins, Predicted intracellular proteins" Autophagy "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 207.8;Renal collecting duct intercalated cells: 118.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.0;plasmacytoid DC: 3.8" "Group enriched" "Detected in many" 4 "dendritic cells: 3.8;granulocytes: 4.0" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063990 Approved Cytosol NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 33: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 95 Cytosol "HPA063990: " "unprognostic (5.56e-2)" "unprognostic (3.58e-2)" "unprognostic (7.20e-2)" "unprognostic (7.05e-2)" "unprognostic (1.78e-2)" "unprognostic (2.16e-1)" "unprognostic (3.68e-2)" "unprognostic (1.03e-1)" "unprognostic (1.32e-1)" "unprognostic (5.22e-2)" "unprognostic (6.73e-2)" "unprognostic (4.18e-1)" "unprognostic (2.61e-3)" "unprognostic (2.84e-2)" "unprognostic (2.80e-1)" "unprognostic (1.62e-2)" "unprognostic (9.64e-2)" "unprognostic (1.15e-1)" "unprognostic (5.39e-2)" "unprognostic (6.95e-3)" "unprognostic (2.52e-1)" "unprognostic (2.14e-2)" "unprognostic (6.91e-3)" "unprognostic (1.14e-1)" "unprognostic (7.86e-2)" "unprognostic (8.18e-3)" "unprognostic (7.03e-2)" "unprognostic (2.15e-1)" "unprognostic (3.01e-1)" "unprognostic (1.44e-2)" "unprognostic (1.43e-1)" ULK2 "ATG1B, KIAA0623, Unc51.2" ENSG00000083290 "Unc-51 like autophagy activating kinase 2" Q8IYT8 17 19770829-19867936 "Enzymes, Predicted intracellular proteins" "Autophagy, Neurogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglia: 134.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 4.0;non-classical monocyte: 3.4" "Lineage enriched" "Detected in single" 5 "monocytes: 4.0" "Cancer enhanced" "Detected in many" "testis cancer: 40.3" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB037021 Approved NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 80: Oligodendrocytes - Myelination" 5 "CAB037021: " "unprognostic (1.53e-1)" "unprognostic (8.96e-2)" "unprognostic (3.58e-1)" "unprognostic (7.27e-2)" "unprognostic (3.91e-1)" "unprognostic (6.50e-2)" "unprognostic (8.47e-2)" "unprognostic (1.60e-1)" "unprognostic (1.43e-2)" "unprognostic (7.80e-2)" "potential prognostic favorable (6.64e-4)" "unprognostic (8.62e-3)" "potential prognostic favorable (6.03e-4)" "unprognostic (1.30e-1)" "unprognostic (8.95e-2)" "unprognostic (1.01e-1)" "unprognostic (4.84e-2)" "potential prognostic unfavorable (6.86e-4)" "unprognostic (1.53e-1)" "unprognostic (5.17e-2)" "unprognostic (1.08e-1)" "potential prognostic favorable (4.21e-4)" "unprognostic (1.36e-1)" "unprognostic (1.45e-1)" "unprognostic (1.17e-1)" "unprognostic (6.83e-2)" "unprognostic (1.56e-1)" "unprognostic (2.43e-1)" "unprognostic (2.50e-1)" "unprognostic (2.12e-1)" "unprognostic (1.51e-1)" ULK3 "DKFZP434C131, FLJ90566" ENSG00000140474 "Unc-51 like kinase 3" Q6PHR2 15 74836118-74843346 "Enzymes, Predicted intracellular proteins" Autophagy "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 258.5;Retinal amacrine cells: 93.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040474 Approved Approved Acrosome NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 24: Non-specific - Transcription" "Cluster 24: Neurons - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 84: Apical squamous epithelium - Cornification" 13 Acrosome "HPA040474: " "unprognostic (1.84e-1)" "unprognostic (2.16e-2)" "unprognostic (1.09e-1)" "unprognostic (1.58e-1)" "unprognostic (3.82e-3)" "unprognostic (1.19e-1)" "unprognostic (1.23e-1)" "unprognostic (2.36e-3)" "unprognostic (7.97e-2)" "unprognostic (5.49e-2)" "potential prognostic favorable (2.53e-6)" "unprognostic (9.71e-3)" "potential prognostic favorable (1.30e-4)" "unprognostic (2.82e-1)" "unprognostic (2.84e-1)" "unprognostic (2.16e-1)" "unprognostic (1.91e-1)" "unprognostic (2.64e-1)" "unprognostic (2.77e-1)" "unprognostic (2.33e-1)" "unprognostic (2.40e-3)" "unprognostic (4.14e-1)" "unprognostic (1.34e-1)" "unprognostic (1.25e-2)" "unprognostic (7.61e-2)" "unprognostic (2.10e-1)" "unprognostic (1.50e-1)" "unprognostic (2.60e-3)" "unprognostic (6.09e-2)" "unprognostic (6.30e-3)" "unprognostic (2.06e-2)" ULK4 "FAM7C1, FLJ20574, REC01035" ENSG00000168038 "Unc-51 like kinase 4" Q96C45 3 41246599-41962130 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 21.9" "Cell type enhanced" "Detected in all" "Choroid plexus epithelial cells: 639.7;Decidual stromal cells: 2242.6;Endometrial ciliated cells: 1030.7;Ependymal cells: 1531.4;Fallopian tube ciliated cells: 726.6;Late spermatids: 699.1;Respiratory ciliated cells: 1485.8" "Group enriched" "Detected in all" 4 "choroid plexus epithelial cell: 580.0;ependymal cell: 1660.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA017930 Uncertain Approved "Primary cilium transition zone,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 34: Ciliated cells - Cilia assembly & function" 2 "Primary cilium transition zone, Cytosol" "HPA017930: " "unprognostic (1.77e-1)" "unprognostic (2.62e-1)" "unprognostic (6.16e-2)" "unprognostic (1.17e-2)" "unprognostic (1.12e-1)" "unprognostic (3.19e-1)" "unprognostic (8.84e-2)" "unprognostic (1.06e-1)" "unprognostic (1.46e-2)" "potential prognostic unfavorable (2.90e-4)" "unprognostic (1.53e-2)" "unprognostic (1.06e-1)" "unprognostic (1.97e-1)" "unprognostic (1.98e-1)" "unprognostic (6.86e-2)" "unprognostic (1.24e-1)" "unprognostic (4.42e-2)" "unprognostic (5.06e-2)" "unprognostic (2.43e-1)" "unprognostic (5.64e-2)" "unprognostic (4.41e-1)" "unprognostic (1.50e-3)" "unprognostic (2.57e-2)" "unprognostic (4.95e-1)" "unprognostic (7.08e-3)" "unprognostic (1.10e-1)" "unprognostic (8.56e-2)" "unprognostic (1.06e-2)" "unprognostic (2.06e-1)" "unprognostic (1.12e-1)" "unprognostic (2.17e-1)" UMAD1 "RPA3-AS1, RPA3OS" ENSG00000219545 "UBAP1-MVB12-associated (UMA) domain containing 1" C9J7I0 7 7640711-7968020 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 14 "Distal convoluted tubule cells: 280.2;Loop of henle epithelial cells: 221.0;Papillary tip epithelial cells: 215.0;Podocytes: 277.5;Proximal tubule cells: 158.7;Renal collecting duct intercalated cells: 373.1;Renal collecting duct principal cells: 223.1;Renal connecting tubule cells: 269.8" "Low cell type specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044806 Approved Approved Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 105: Non-specific - Mixed function" 3 Nucleoplasm "HPA044806: " "unprognostic (2.47e-1)" "unprognostic (1.41e-2)" "unprognostic (1.13e-1)" "unprognostic (1.72e-2)" "unprognostic (7.72e-2)" "unprognostic (9.22e-3)" "unprognostic (4.07e-3)" "unprognostic (9.47e-2)" "unprognostic (2.76e-2)" "potential prognostic favorable (6.63e-11)" "unprognostic (6.24e-3)" "unprognostic (1.36e-1)" "unprognostic (1.61e-2)" "unprognostic (6.03e-2)" "unprognostic (1.69e-1)" "unprognostic (3.22e-2)" "unprognostic (3.42e-2)" "unprognostic (3.91e-2)" "potential prognostic unfavorable (2.30e-4)" "unprognostic (7.31e-2)" "unprognostic (3.63e-2)" "unprognostic (1.98e-1)" "unprognostic (5.53e-2)" "unprognostic (1.74e-1)" "unprognostic (3.41e-2)" "unprognostic (3.71e-2)" "unprognostic (3.27e-1)" "unprognostic (1.12e-1)" "unprognostic (4.06e-2)" UMOD ENSG00000169344 Uromodulin P07911 16 20333051-20356301 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Ciliopathy, Disease variant, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 515 "kidney: 2126.7" "Cell type enriched" "Detected in some" 12 "Loop of henle epithelial cells: 1187.8" "Not detected" "Not detected" "Group enriched" "Detected in some" 16 "Kidney Chromophobe (TCGA): 49.4;Kidney Renal Clear Cell Carcinoma (TCGA): 13.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Ascending Loop of Henle cells, Prostate - Prostate glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB009446, HPA043420, HPA054721" Enhanced "Secreted in other tissues" Immunity NA NA 35000000 "Cluster 72: Kidney - Transmembrane transport" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" "CAB009446: , HPA043420: , HPA054721: " "unprognostic (7.04e-2)" "unprognostic (3.39e-1)" "potential prognostic favorable (6.29e-4)" "unprognostic (6.28e-2)" "unprognostic (1.15e-1)" UMODL1 ENSG00000177398 "Uromodulin like 1" Q5DID0 21 42062959-42143453 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "fallopian tube: 1.0" "Cell type enriched" "Detected in some" 6 "Thymocytes: 78.8" "Cell type enhanced" "Detected in some" "ependymal cell: 4.8" "Cancer enriched" "Detected in single" 4 "Kidney Chromophobe (TCGA): 1.1" "Region enhanced" "Detected in some" "cerebral cortex: 4.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pituitary gland - Corticotropes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA067245 Uncertain NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 107: Ciliated cells - Cilia assembly & function" "HPA067245: " "unprognostic (3.83e-1)" "unprognostic (3.64e-1)" UMPS ENSG00000114491 "Uridine monophosphate synthetase" P11172 3 124730433-124749273 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Pyrimidine biosynthesis" "Decarboxylase, Glycosyltransferase, Lyase, Multifunctional enzyme, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 86.3;Syncytiotrophoblasts: 139.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036178, HPA036179" Uncertain Approved Cytosol NA NA 8700 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 34: Non-specific - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 3 Cytosol "HPA036178: , HPA036179: " "unprognostic (6.98e-2)" "unprognostic (9.82e-2)" "unprognostic (3.23e-1)" "unprognostic (3.47e-1)" "unprognostic (1.13e-1)" "unprognostic (5.23e-3)" "unprognostic (1.33e-1)" "unprognostic (1.25e-2)" "unprognostic (1.07e-3)" "unprognostic (8.59e-3)" "validated prognostic favorable (2.01e-4)" "validated prognostic favorable (1.55e-5)" "unprognostic (4.96e-2)" "unprognostic (8.86e-2)" "potential prognostic unfavorable (9.64e-4)" "unprognostic (4.16e-2)" "unprognostic (5.21e-2)" "unprognostic (4.49e-2)" "unprognostic (1.46e-1)" "unprognostic (3.64e-2)" "unprognostic (3.61e-2)" "unprognostic (1.77e-1)" "unprognostic (1.48e-1)" "unprognostic (2.92e-3)" "unprognostic (1.45e-2)" "unprognostic (1.28e-1)" "unprognostic (1.25e-1)" "unprognostic (1.27e-1)" "unprognostic (4.35e-1)" "unprognostic (5.05e-3)" "unprognostic (7.82e-2)" UNC119 "HRG4, POC7, POC7A" ENSG00000109103 "Unc-119 lipid binding chaperone" Q13432 17 28546708-28552631 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Endocytosis, Protein transport, Sensory transduction, Transport, Vision" "Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 17 "retina: 1084.9" "Cell type enhanced" "Detected in some" "Astrocytes: 7.3;Bergmann glia: 6.8;Brain excitatory neurons: 10.2;Brain inhibitory neurons: 11.1;Choroid plexus epithelial cells: 14.7;Cone photoreceptor cells: 8.3;Ependymal cells: 4.5;Microglia: 9.9;Oligodendrocyte progenitor cells: 9.9;Other brain neurons: 17.1;Retinal pigment epithelial cells: 4.3;Rod photoreceptor cells: 11.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041912 Enhanced NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 42: Retina - Visual perception" "Cluster 1: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 22: Non-specific - Basic cellular functions" 56 "HPA041912: " "unprognostic (6.72e-2)" "unprognostic (6.19e-2)" "unprognostic (1.44e-1)" "unprognostic (2.04e-2)" "unprognostic (2.95e-2)" "unprognostic (3.14e-3)" "potential prognostic unfavorable (8.67e-5)" "unprognostic (7.05e-2)" "unprognostic (3.76e-1)" "unprognostic (2.65e-2)" "validated prognostic unfavorable (1.72e-5)" "validated prognostic unfavorable (1.13e-4)" "unprognostic (7.07e-2)" "unprognostic (7.40e-3)" "unprognostic (7.75e-2)" "unprognostic (8.28e-2)" "unprognostic (3.42e-1)" "unprognostic (3.28e-2)" "unprognostic (1.89e-2)" "unprognostic (1.67e-2)" "unprognostic (4.25e-3)" "unprognostic (6.54e-3)" "unprognostic (1.89e-2)" "unprognostic (1.57e-1)" "unprognostic (1.20e-1)" "unprognostic (7.12e-2)" "potential prognostic unfavorable (2.70e-4)" "unprognostic (2.07e-1)" "unprognostic (5.15e-2)" "potential prognostic unfavorable (1.34e-5)" "unprognostic (1.13e-1)" UNC119B "MGC5139, POC7B" ENSG00000175970 "Unc-119 lipid binding chaperone B" A6NIH7 12 120710458-120723640 "Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal efferent duct ciliated cells: 65.9;Fallopian tube ciliated cells: 62.7;Respiratory ciliated cells: 71.5" "Cell type enhanced" "Detected in all" "ependymal cell: 53.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skin - Macrophages, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077812 Enhanced Uncertain "Cytokinetic bridge,Mitotic spindle,Cytosol,Flagellar centriole,Mid piece,Principal piece,End piece,Annulus" Yes No "Cluster 33: Non-specific - ATP binding" "Cluster 65: Brain - Transcription" "Cluster 46: Brainstem - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 107: Ciliated cells - Cilia assembly & function" 21 "Cytokinetic bridge, Mitotic spindle, Cytosol, Flagellar centriole, Annulus" "Mid piece, Principal piece, End piece" "HPA077812: " "unprognostic (3.21e-1)" "unprognostic (9.47e-2)" "unprognostic (1.58e-1)" "unprognostic (6.09e-2)" "unprognostic (1.10e-2)" "unprognostic (1.99e-1)" "unprognostic (2.45e-1)" "unprognostic (1.72e-2)" "unprognostic (1.63e-1)" "unprognostic (3.32e-3)" "validated prognostic favorable (7.13e-9)" "validated prognostic favorable (1.86e-4)" "unprognostic (4.25e-2)" "unprognostic (2.61e-3)" "unprognostic (1.25e-3)" "unprognostic (2.14e-1)" "unprognostic (3.10e-1)" "unprognostic (7.06e-2)" "unprognostic (4.34e-3)" "unprognostic (9.71e-2)" "unprognostic (2.87e-2)" "unprognostic (2.68e-3)" "unprognostic (1.05e-1)" "unprognostic (1.93e-2)" "unprognostic (1.05e-1)" "potential prognostic unfavorable (9.09e-4)" "unprognostic (3.79e-2)" "unprognostic (2.41e-2)" "unprognostic (1.42e-1)" "unprognostic (1.27e-1)" "unprognostic (1.17e-1)" UNC13A "KIAA1032, Munc13-1" ENSG00000130477 "Unc-13 homolog A" Q9UPW8 19 17601336-17688365 "Predicted intracellular proteins" "Differentiation, Exocytosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "brain: 40.0;pituitary gland: 30.1;retina: 17.1" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 74.5;Brain excitatory neurons: 103.1;Brain inhibitory neurons: 94.8;Cone photoreceptor cells: 97.3;Corticotrophs: 121.6;Gonadotrophs: 222.2;Lactotrophs: 202.1;Other brain neurons: 72.9;Pancreatic islet cells: 126.6;Retinal amacrine cells: 147.7;Retinal bipolar cells: 139.5;Retinal ganglion cells: 193.1;Retinal horizontal cells: 296.5;Rod photoreceptor cells: 95.9;Somatotrophs: 143.2;Thyrotrophs: 99.9" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Glioblastoma Multiforme (TCGA): 4.9;Pancreatic Adenocarcinoma (TCGA): 2.1;Testicular Germ Cell Tumor (TCGA): 2.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 19.0;Rhabdoid: 30.1" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" "unprognostic (2.78e-1)" "unprognostic (1.71e-1)" "unprognostic (1.34e-1)" "unprognostic (4.18e-3)" "unprognostic (2.05e-3)" "unprognostic (3.74e-3)" "unprognostic (5.29e-2)" "unprognostic (9.07e-2)" UNC13B "hmunc13, Munc13-2, UNC13, Unc13h2" ENSG00000198722 "Unc-13 homolog B" O14795 9 35161992-35405338 "Predicted intracellular proteins" Exocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 387.0;Alveolar cells type 2: 521.9;Cone photoreceptor cells: 447.1;Goblet cells: 456.0;Myonuclei: 537.4;Prostatic glandular cells: 845.4;Rod photoreceptor cells: 468.7;Transitional alveolar cells: 606.3" "Cell type enriched" "Detected in all" 4 "endothelial cell: 673.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Spleen - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024493, HPA062300" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles,Intermediate filaments" Yes No "Cluster 47: Testis - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 13 Vesicles "Nucleoplasm, Golgi apparatus, Intermediate filaments" "HPA024493: , HPA062300: " "unprognostic (3.47e-1)" "unprognostic (5.31e-3)" "unprognostic (4.01e-1)" "unprognostic (6.15e-2)" "unprognostic (6.81e-2)" "unprognostic (1.93e-1)" "unprognostic (1.01e-1)" "unprognostic (9.56e-2)" "potential prognostic favorable (1.16e-4)" "unprognostic (9.76e-2)" "potential prognostic favorable (4.58e-8)" "unprognostic (1.51e-3)" "potential prognostic favorable (6.90e-5)" "unprognostic (1.02e-1)" "unprognostic (1.42e-2)" "potential prognostic favorable (3.07e-4)" "unprognostic (9.71e-2)" "unprognostic (1.86e-1)" "unprognostic (6.17e-3)" "unprognostic (2.63e-1)" "unprognostic (7.07e-2)" "unprognostic (5.31e-2)" "unprognostic (1.22e-1)" "unprognostic (1.71e-1)" "unprognostic (1.00e-2)" "unprognostic (8.83e-2)" "unprognostic (2.56e-2)" "unprognostic (1.06e-1)" "unprognostic (1.98e-1)" "unprognostic (1.86e-2)" "unprognostic (1.12e-1)" UNC13C "DKFZp547H074, Munc13-3" ENSG00000137766 "Unc-13 homolog C" Q8NB66 15 53978201-54628707 "Predicted intracellular proteins" Exocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 40.2;retina: 17.5" "Cell type enhanced" "Detected in many" "Bergmann glia: 337.4;Brain excitatory neurons: 772.5;Brain inhibitory neurons: 342.0;Lactotrophs: 220.0;Myonuclei: 820.9;Oocytes: 727.6;Pituicytes/FSCs: 288.2;Renal collecting duct principal cells: 276.8;Retinal amacrine cells: 800.2;Retinal bipolar cells: 658.8;Retinal ganglion cells: 394.0;Rod photoreceptor cells: 288.8" "Cell type enhanced" "Detected in all" "mammillary body: 1477.0;midbrain-derived inhibitory: 1643.2;upper rhombic lip: 2153.8" "Cancer enhanced" "Detected in some" "Kidney Chromophobe (TCGA): 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 16 "lymphoma: 14.5;Myeloma: 57.6" "Adipose subcutaneous - Smooth muscle cells, Colon - Enteric glia cells, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 7 "cerebellum: 279.2" HPA041516 Approved Vesicles,Cytosol NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 35: Non-specific - DNA binding" "Cluster 55: Lymphoma - Immune response" "Cluster 2: Cerebellar granular cells - Neuronal signaling" Vesicles Cytosol "HPA041516: " "unprognostic (2.46e-1)" "unprognostic (1.86e-1)" "potential prognostic favorable (4.59e-4)" UNC13D Munc13-4 ENSG00000092929 "Unc-13 homolog D" Q70J99 17 75827225-75844785 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Exocytosis "Familial hemophagocytic lymphohistiocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 66.9;lymphoid tissue: 65.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 213.5;Esophageal apical cells: 95.9;Hofbauer cells: 110.0;Megakaryocyte progenitors: 77.9;Megakaryocytes: 86.5;Neutrophil progenitors: 101.3;Neutrophils: 230.6;Platelets: 156.3;Syncytiotrophoblasts: 76.1" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 26.1;leukocyte: 56.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Thyroid gland - T-cells" "Region enriched" "Detected in single" 6 "cerebellum: 5.0" "Low region specificity" "Detected in many" "HPA067117, HPA073525" Enhanced Supported Vesicles,Cytosol NA NA 1700000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 2 Cytosol Vesicles "HPA067117: , HPA073525: " "unprognostic (1.59e-1)" "unprognostic (6.45e-3)" "unprognostic (1.26e-1)" "unprognostic (1.72e-3)" "unprognostic (3.85e-1)" "unprognostic (1.23e-1)" "unprognostic (2.82e-2)" "unprognostic (2.51e-1)" "potential prognostic favorable (1.17e-4)" "unprognostic (1.56e-2)" "potential prognostic unfavorable (6.14e-5)" "unprognostic (1.60e-1)" "unprognostic (1.45e-2)" "unprognostic (3.15e-1)" "unprognostic (5.67e-2)" "unprognostic (1.31e-1)" "unprognostic (4.32e-2)" "unprognostic (1.48e-3)" "unprognostic (4.79e-2)" "unprognostic (3.33e-2)" "unprognostic (2.87e-2)" "validated prognostic unfavorable (6.69e-4)" "validated prognostic unfavorable (5.79e-5)" "unprognostic (1.52e-1)" "unprognostic (3.78e-2)" "unprognostic (3.20e-2)" "unprognostic (1.19e-1)" "unprognostic (5.61e-2)" "unprognostic (2.25e-1)" "unprognostic (3.64e-2)" "unprognostic (1.65e-1)" UNC45A "GC-UNC45, SMAP-1" ENSG00000140553 "Unc-45 myosin chaperone A" Q9H3U1 15 90930180-90954093 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Myogenesis" "Chaperone, Developmental protein" Deafness "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Retinal ganglion cells: 123.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039228 Approved Supported "Nuclear speckles,Cytosol" NA NA 77000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 45: Non-specific - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 62: Smooth muscle cells - Muscle contraction" 32 "Nuclear speckles" Cytosol "HPA039228: " "unprognostic (1.74e-1)" "unprognostic (2.92e-1)" "unprognostic (9.51e-2)" "unprognostic (2.56e-1)" "unprognostic (2.52e-1)" "unprognostic (2.10e-1)" "unprognostic (6.83e-2)" "unprognostic (1.15e-2)" "unprognostic (1.87e-3)" "unprognostic (1.01e-2)" "potential prognostic favorable (1.32e-7)" "unprognostic (6.75e-3)" "unprognostic (9.62e-3)" "validated prognostic unfavorable (5.28e-4)" "validated prognostic unfavorable (3.27e-5)" "unprognostic (5.87e-2)" "unprognostic (1.01e-2)" "unprognostic (9.41e-2)" "unprognostic (9.19e-2)" "unprognostic (1.24e-1)" "unprognostic (6.25e-2)" "unprognostic (2.31e-1)" "unprognostic (1.36e-1)" "unprognostic (7.90e-2)" "unprognostic (1.21e-1)" "unprognostic (3.23e-2)" "unprognostic (3.66e-1)" "unprognostic (7.83e-2)" "unprognostic (2.50e-1)" "unprognostic (1.94e-1)" "unprognostic (1.73e-1)" UNC45B "CMYA4, UNC45" ENSG00000141161 "Unc-45 myosin chaperone B" Q8IWX7 17 35147817-35189345 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Myogenesis" "Chaperone, Developmental protein" "Cataract, Disease variant, Myofibrillar myopathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 26 "heart muscle: 93.9;skeletal muscle: 184.2;tongue: 141.9" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 48.0;Early spermatids: 37.6;Late spermatids: 85.6;Myonuclei: 82.4;Thymic myoid cells: 34.0" "Cell type enriched" "Detected in single" 4 "vascular associated smooth muscle cell: 2.3" "Group enriched" "Detected in some" 6 "Head and Neck Squamous Cell Carcinoma (TCGA): 1.6;Testicular Germ Cell Tumor (TCGA): 1.9" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.1" "Lineage enriched" "Detected in single" 10 "T-cells: 1.1" "Cancer enriched" "Detected in single" 17 "Sarcoma: 1.7" "Heart muscle - Cardiomyocytes, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA017861 Approved Cytosol NA NA "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 7 Cytosol "HPA017861: " "unprognostic (5.80e-2)" "unprognostic (1.86e-2)" UNC50 "GMH1, UNCL, URP" ENSG00000115446 "Unc-50 inner nuclear membrane RNA binding protein" Q53HI1 2 98608579-98618515 "Essential proteins, Predicted membrane proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 198.8;Syncytiotrophoblasts: 196.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027009 Approved NA NA "Cluster 41: Basophils - Unknown function" "Cluster 22: Epididymis - Mixed function" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 29 "HPA027009: " "unprognostic (2.84e-1)" "potential prognostic unfavorable (7.67e-4)" "unprognostic (3.73e-2)" "unprognostic (9.02e-3)" "unprognostic (1.35e-1)" "unprognostic (2.46e-1)" "unprognostic (6.82e-2)" "unprognostic (8.56e-2)" "unprognostic (9.06e-3)" "unprognostic (1.65e-1)" "potential prognostic favorable (4.76e-4)" "unprognostic (3.38e-2)" "unprognostic (1.27e-1)" "validated prognostic unfavorable (4.38e-6)" "validated prognostic unfavorable (4.90e-4)" "unprognostic (4.45e-1)" "unprognostic (1.26e-1)" "unprognostic (7.15e-2)" "unprognostic (9.50e-2)" "unprognostic (1.93e-1)" "potential prognostic unfavorable (5.33e-4)" "unprognostic (1.38e-1)" "unprognostic (1.13e-1)" "unprognostic (1.70e-1)" "unprognostic (8.88e-2)" "unprognostic (8.87e-2)" "unprognostic (5.38e-2)" "unprognostic (1.57e-1)" "unprognostic (1.72e-1)" "unprognostic (1.96e-1)" "unprognostic (3.31e-1)" UNC5A "KIAA1976, UNC5H1" ENSG00000113763 "Unc-5 netrin receptor A" Q6ZN44 5 176810519-176880898 "Predicted membrane proteins" Apoptosis "Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 58.7" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 42.5;Brain excitatory neurons: 55.1;Brain inhibitory neurons: 31.0;Corticotrophs: 22.2;Late spermatids: 11.0;Müller glia: 22.6;Oligodendrocyte progenitor cells: 10.7;Other brain neurons: 21.5;Retinal amacrine cells: 47.4;Retinal horizontal cells: 12.0;Rod photoreceptor cells: 12.1" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 11.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 18.5" "Adrenal gland - Adrenal medulla cells, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Corticotropes, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071450 Approved "Plasma membrane,Cytosol" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 53: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 35: Neurons - Synaptic function & neurogenesis" 2 "Plasma membrane, Cytosol" "HPA071450: " "unprognostic (1.62e-2)" "unprognostic (4.37e-2)" "unprognostic (5.48e-2)" "unprognostic (5.10e-2)" "potential prognostic favorable (6.55e-4)" "potential prognostic unfavorable (1.36e-4)" "unprognostic (3.69e-1)" "unprognostic (4.99e-2)" "unprognostic (7.69e-2)" "unprognostic (3.88e-1)" "unprognostic (1.64e-2)" "unprognostic (7.37e-2)" "unprognostic (1.21e-1)" "unprognostic (2.95e-1)" "unprognostic (3.18e-2)" UNC5B "p53RDL1, UNC5H2" ENSG00000107731 "Unc-5 netrin receptor B" Q8IZJ1 10 71212570-71302864 "Plasma proteins, Predicted membrane proteins" "Angiogenesis, Apoptosis" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 117.0;Esophageal apical cells: 73.1;Esophageal suprabasal cells: 90.5;Lymphatic endothelial cells: 72.8;Müller glia: 96.3;Oligodendrocytes: 110.0;Prostatic hillock cells: 130.3;Retinal amacrine cells: 83.0;Retinal horizontal cells: 98.2" "Cell type enhanced" "Detected in many" "oligodendrocyte: 137.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 75.9" "Skin - Inner root sheath cells, Skin - Outer root sheath cells, Spleen - Fibroblasts_1, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076687 Approved NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 6: Non-specific - Immune response" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 5 "HPA076687: " "unprognostic (7.19e-2)" "unprognostic (2.45e-2)" "unprognostic (3.86e-1)" "unprognostic (3.29e-1)" "unprognostic (8.34e-2)" "unprognostic (6.05e-2)" "unprognostic (6.56e-2)" "unprognostic (1.27e-1)" "unprognostic (1.03e-1)" "potential prognostic unfavorable (8.08e-4)" "potential prognostic favorable (5.53e-4)" "unprognostic (3.22e-3)" "unprognostic (3.19e-2)" "potential prognostic unfavorable (7.68e-6)" "unprognostic (3.80e-1)" "unprognostic (1.12e-1)" "unprognostic (2.22e-3)" "unprognostic (2.35e-2)" "unprognostic (1.50e-1)" "unprognostic (1.46e-3)" "unprognostic (6.20e-3)" "unprognostic (1.86e-2)" "unprognostic (1.57e-1)" "unprognostic (7.20e-2)" "unprognostic (9.99e-2)" "unprognostic (1.68e-2)" "unprognostic (2.19e-3)" "unprognostic (1.60e-1)" "unprognostic (1.60e-1)" "unprognostic (6.00e-2)" "unprognostic (7.45e-3)" UNC5C ENSG00000182168 "Unc-5 netrin receptor C" O95185 4 95162504-95549206 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Developmental protein, Receptor" "Alzheimer disease, Amyloidosis, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 11.1" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 1023.6;Adrenal medulla cells: 2478.4;Bergmann glia: 445.7;Brain excitatory neurons: 430.2;Brain inhibitory neurons: 688.1;Leydig cells: 514.5;Medullary thymic epithelial cells: 456.0;Oligodendrocyte progenitor cells: 459.7;Oligodendrocytes: 2265.6;Other brain neurons: 696.0;Podocytes: 966.3;Rod photoreceptor cells: 456.5;Sertoli cells: 464.5" "Cell type enhanced" "Detected in all" "cerebellar inhibitory: 3918.2" "Cancer enriched" "Detected in many" 4 "Thyroid Carcinoma (TCGA): 11.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "Neuroblastoma: 56.0" "Breast - Breast myoepithelial cells, Liver - Hepatic stellate cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 290000 "Cluster 65: Brain - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 80: Oligodendrocytes - Myelination" 1 "unprognostic (2.69e-1)" "unprognostic (2.05e-2)" "unprognostic (2.28e-1)" "unprognostic (5.07e-2)" "unprognostic (1.26e-2)" "unprognostic (9.91e-3)" "unprognostic (1.12e-1)" "unprognostic (4.72e-2)" "unprognostic (4.29e-2)" "unprognostic (1.79e-1)" "unprognostic (3.46e-2)" "unprognostic (6.90e-2)" "unprognostic (1.83e-2)" "unprognostic (9.83e-2)" "unprognostic (2.30e-1)" UNC5CL "MGC34763, ZUD" ENSG00000124602 "Unc-5 family C-terminal like" Q8IV45 6 41026895-41039221 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 34.9;kidney: 54.2;liver: 50.3;pancreas: 35.7;stomach 1: 22.3" "Cell type enhanced" "Detected in many" "Cholangiocytes: 26.4;Enterocytes: 36.4;Foveolar cells: 83.5;Gastric progenitor cells: 26.9;Hepatocytes: 34.7;Mucous neck cells: 52.1;Pancreatic acinar cells: 16.4;Pancreatic duct cells: 19.5;Pancreatic islet cells: 16.1;Proximal tubule cells: 40.1;Tuft cells: 23.1" "Cell type enhanced" "Detected in some" "astrocyte: 3.7" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 33.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA015725 Enhanced Supported Centrosome,Cytosol NA NA "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 28: Non-specific - Nuclear processes" "Cluster 68: Foveolar cells - Mucosal defense" 5 Cytosol Centrosome "HPA015725: " "unprognostic (3.60e-2)" "unprognostic (3.38e-2)" "unprognostic (9.49e-3)" "unprognostic (2.75e-3)" "unprognostic (2.16e-1)" "unprognostic (8.67e-2)" "unprognostic (1.59e-1)" "unprognostic (1.15e-2)" "unprognostic (1.30e-2)" "potential prognostic favorable (6.17e-4)" "unprognostic (8.30e-2)" "unprognostic (1.45e-1)" "unprognostic (1.03e-1)" "unprognostic (8.21e-2)" "unprognostic (2.18e-2)" "unprognostic (2.89e-1)" "unprognostic (2.43e-1)" "unprognostic (1.57e-2)" "unprognostic (5.15e-2)" "unprognostic (1.27e-1)" "unprognostic (2.67e-2)" "unprognostic (6.88e-2)" "unprognostic (1.04e-2)" "unprognostic (1.70e-1)" "unprognostic (1.29e-1)" "unprognostic (1.67e-1)" "unprognostic (1.54e-1)" "unprognostic (2.23e-1)" UNC5D "KIAA1777, Unc5h4" ENSG00000156687 "Unc-5 netrin receptor D" Q6UXZ4 8 35235475-35796550 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.8;intestine: 5.6;prostate: 4.5;retina: 4.5" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 404.2;Brain excitatory neurons: 464.8;Brain inhibitory neurons: 1091.6;Gonadotrophs: 321.8;Lactotrophs: 891.0;Other brain neurons: 999.9;Pituicytes/FSCs: 1683.1;Pituitary stem cells: 452.7;Podocytes: 376.6;Prostatic glandular cells: 683.6;Retinal amacrine cells: 393.2;Retinal bipolar cells: 791.8;Retinal ganglion cells: 706.9;Retinal horizontal cells: 759.3" "Cell type enhanced" "Detected in all" "LAMP5-LHX6 and Chandelier: 4656.9" "Cancer enhanced" "Detected in some" "Kidney Chromophobe (TCGA): 5.0;Kidney Renal Papillary Cell Carcinoma (TCGA): 3.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "testis cancer: 2.6;thyroid cancer: 3.0" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042940 Uncertain NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 6: Leukemia - Signal transduction" "Cluster 109: Neurons - Neuronal signaling" "HPA042940: " "unprognostic (5.77e-2)" "unprognostic (3.83e-2)" "unprognostic (2.40e-1)" "unprognostic (8.97e-2)" "unprognostic (2.17e-3)" "unprognostic (3.01e-1)" UNC79 KIAA1409 ENSG00000133958 "Unc-79 homolog, NALCN channel complex subunit" Q9P2D8 14 93333219-93707876 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 12.8;pituitary gland: 11.1;retina: 5.0" "Cell type enhanced" "Detected in some" "Astrocytes: 154.1;Bergmann glia: 126.6;Brain excitatory neurons: 588.9;Brain inhibitory neurons: 653.2;Ependymal cells: 245.9;Oligodendrocyte progenitor cells: 397.8;Oligodendrocytes: 218.3;Other brain neurons: 472.3" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 8.1;thyroid cancer: 2.5" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Lung - Respiratory ciliated cells, Stomach - Gastric enteroendocrine cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071881 Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 37: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" "Plasma membrane" Nucleoplasm "HPA071881: " "unprognostic (4.28e-3)" UNC80 "C2orf21, FLJ33496, KIAA1843, UNC-80" ENSG00000144406 "Unc-80 homolog, NALCN channel complex subunit" Q8N2C7 2 209771832-209999300 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 29.7;pituitary gland: 12.8;retina: 17.6" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 648.9;Brain excitatory neurons: 464.8;Brain inhibitory neurons: 467.5;Corticotrophs: 769.0;Gonadotrophs: 628.1;Lactotrophs: 786.5;Oligodendrocyte progenitor cells: 654.4;Other brain neurons: 345.9;Retinal bipolar cells: 317.4;Rod photoreceptor cells: 275.7;Sertoli cells: 806.8;Somatotrophs: 785.0;Thyrotrophs: 816.7" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 1.9;Prostate Adenocarcinoma (TCGA): 1.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 4.2;prostate cancer: 3.0" "Colon - Colon enteroendocrine cells, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Alpha cells, Pancreas - Beta cells, Prostate - Prostate glandular cells, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042472, HPA050959" Enhanced Approved "Nuclear bodies,Vesicles" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" "Nuclear bodies" Vesicles "HPA042472: , HPA050959: " "unprognostic (1.98e-1)" "potential prognostic favorable (5.79e-4)" "unprognostic (1.30e-2)" "unprognostic (1.97e-2)" "unprognostic (2.65e-1)" UNC93A "dJ366N23.1, dJ366N23.2" ENSG00000112494 "Unc-93 homolog A" Q86WB7 6 167271169-167316014 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "esophagus: 4.8;intestine: 9.0;liver: 13.1;skin 1: 18.2" "Group enriched" "Detected in some" 4 "Esophageal apical cells: 38.3;Oocytes: 36.8;Renal collecting duct principal cells: 36.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 9.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "colorectal cancer: 6.8;Gastric cancer: 7.1;liver cancer: 3.5" "Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA035729 Uncertain NA NA "Cluster 58: Skin - Keratinization" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 1 "HPA035729: " "unprognostic (2.58e-1)" "unprognostic (2.14e-1)" "unprognostic (2.30e-2)" "unprognostic (1.40e-1)" "unprognostic (3.89e-2)" "unprognostic (3.18e-1)" "potential prognostic unfavorable (6.34e-4)" "unprognostic (1.76e-1)" "unprognostic (3.87e-1)" "unprognostic (2.59e-1)" "unprognostic (9.24e-2)" "unprognostic (4.12e-1)" "unprognostic (7.78e-2)" "unprognostic (1.70e-1)" UNC93B1 UNC93 ENSG00000110057 "Unc-93 homolog B1, TLR signaling regulator" Q9H1C4 11 67991100-68004982 "Disease related genes, Essential proteins, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Adaptive immunity, Antiviral defense, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 74.4" "Cell type enhanced" "Detected in many" "Fallopian tube ciliated cells: 86.0;Hofbauer cells: 103.8;Macrophages: 83.3;Microglia: 79.6;pDCs: 179.6;Respiratory ciliated cells: 161.1" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 92.3;leukocyte: 31.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 18.3" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Lung - Macrophages, Skeletal muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038716, HPA038717, HPA042803" Approved Approved Nucleoplasm No No "Cluster 29: Non-specific - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 111 Nucleoplasm "HPA038716: , HPA038717: , HPA042803: " "unprognostic (6.20e-2)" "potential prognostic unfavorable (6.68e-4)" "unprognostic (9.80e-2)" "unprognostic (2.66e-1)" "unprognostic (1.31e-1)" "unprognostic (2.27e-2)" "unprognostic (6.08e-2)" "unprognostic (9.72e-3)" "unprognostic (6.01e-2)" "unprognostic (8.79e-2)" "unprognostic (3.53e-2)" "unprognostic (4.92e-3)" "unprognostic (1.54e-2)" "unprognostic (1.37e-2)" "unprognostic (1.49e-1)" "unprognostic (4.60e-2)" "unprognostic (4.95e-2)" "potential prognostic unfavorable (5.61e-4)" "unprognostic (9.45e-2)" "unprognostic (5.27e-2)" "unprognostic (9.45e-3)" "potential prognostic unfavorable (5.19e-4)" "unprognostic (3.97e-1)" "unprognostic (1.07e-1)" "unprognostic (2.41e-1)" "unprognostic (6.18e-2)" "unprognostic (1.11e-1)" "unprognostic (7.01e-2)" "unprognostic (3.46e-3)" "unprognostic (1.02e-1)" "unprognostic (7.47e-2)" UNCX Uncx4.1 ENSG00000164853 "UNC homeobox" A6NJT0 7 1232872-1237326 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "brain: 22.0" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 10.7;Brain inhibitory neurons: 5.2;Loop of henle epithelial cells: 6.5;Other brain neurons: 3.5;Retinal horizontal cells: 2.0;Somatotrophs: 2.2;Thyrotrophs: 2.2" "Cell type enhanced" "Detected in some" "midbrain-derived inhibitory: 32.2;upper rhombic lip: 28.9" "Not detected" "Not detected" "Region enriched" "Detected in many" 5 "cerebellum: 36.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 1.0;Leukemia: 1.7" "Kidney - Ascending Loop of Henle cells" "Region enriched" "Detected in single" 5 "cerebellum: 3.2" "Region enriched" "Detected in many" 8 "cerebellum: 11.5" HPA063294 Approved Nucleoplasm NA NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 11: Neuronal - Sensory perception" "Cluster 2: Cerebellar granular cells - Neuronal signaling" Nucleoplasm "HPA063294: " UNG "DGU, HIGM4, UDG, UNG1, UNG2" ENSG00000076248 "Uracil DNA glycosylase" P13051 12 109097597-109126725 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair, Host-virus interaction" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 76.2;Differentiating spermatogonia: 107.5;Migrating cytotrophoblasts: 84.8;Oocytes: 170.4;Parietal cells: 79.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011605, HPA071225" Uncertain Supported Nucleoplasm,Mitochondria NA Yes "Cluster 3: Non-specific - Nuclear processes" "Cluster 76: Non-specific - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 10 Nucleoplasm Mitochondria "CAB011605: , HPA071225: " "unprognostic (1.29e-1)" "unprognostic (3.39e-2)" "unprognostic (7.25e-3)" "unprognostic (2.25e-1)" "unprognostic (4.27e-2)" "unprognostic (1.07e-1)" "unprognostic (1.90e-1)" "unprognostic (1.73e-1)" "unprognostic (1.90e-1)" "unprognostic (1.32e-1)" "potential prognostic favorable (1.23e-4)" "unprognostic (4.48e-2)" "unprognostic (5.68e-2)" "validated prognostic unfavorable (5.94e-6)" "validated prognostic unfavorable (5.42e-6)" "potential prognostic unfavorable (6.92e-4)" "unprognostic (3.04e-3)" "unprognostic (9.68e-2)" "unprognostic (5.83e-2)" "unprognostic (2.05e-1)" "unprognostic (5.94e-2)" "unprognostic (1.26e-2)" "unprognostic (1.71e-1)" "unprognostic (3.16e-1)" "potential prognostic favorable (7.28e-4)" "unprognostic (2.99e-2)" "potential prognostic unfavorable (9.15e-4)" "unprognostic (4.59e-2)" "unprognostic (1.74e-1)" "unprognostic (4.47e-2)" "unprognostic (2.92e-1)" UNK "KIAA1753, ZC3H5, ZC3HDC5" ENSG00000132478 "Unk zinc finger" Q9C0B0 17 75784806-75825799 "Predicted intracellular proteins" "Translation regulation" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 203.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023636, HPA027962" Uncertain Supported "Cytosol,Cytoplasmic bodies" NA NA "Cluster 64: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 6 "Cytosol, Cytoplasmic bodies" "HPA023636: , HPA027962: " "unprognostic (4.07e-3)" "unprognostic (2.78e-1)" "unprognostic (3.47e-1)" "unprognostic (7.19e-2)" "unprognostic (2.14e-1)" "unprognostic (6.05e-2)" "unprognostic (3.55e-1)" "unprognostic (2.51e-2)" "potential prognostic favorable (4.12e-4)" "unprognostic (3.27e-2)" "unprognostic (4.70e-2)" "unprognostic (5.08e-2)" "unprognostic (1.73e-1)" "unprognostic (3.14e-3)" "unprognostic (5.76e-2)" "unprognostic (1.55e-1)" "unprognostic (2.18e-1)" "unprognostic (2.43e-1)" "unprognostic (4.23e-2)" "unprognostic (3.38e-1)" "unprognostic (9.21e-3)" "unprognostic (1.18e-3)" "unprognostic (2.16e-3)" "unprognostic (4.90e-3)" "unprognostic (3.54e-2)" "potential prognostic favorable (2.78e-4)" "unprognostic (3.86e-2)" "unprognostic (5.63e-2)" "unprognostic (1.16e-1)" "unprognostic (4.34e-2)" "unprognostic (3.52e-1)" UNKL "C16orf28, FLJ23360, ZC3H5L, ZC3HDC5L" ENSG00000059145 "Unk like zinc finger" Q9H9P5 16 1363205-1414751 "Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055801, HPA073949" Uncertain Supported Cytosol NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 24: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 54: Non-specific - Transcription" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 7 Cytosol "HPA055801: , HPA073949: " "unprognostic (4.15e-2)" "unprognostic (9.76e-2)" "unprognostic (4.00e-1)" "unprognostic (1.78e-2)" "unprognostic (7.22e-2)" "unprognostic (6.26e-2)" "unprognostic (9.42e-2)" "unprognostic (2.40e-1)" "unprognostic (1.04e-2)" "unprognostic (1.61e-1)" "unprognostic (4.55e-2)" "unprognostic (3.84e-1)" "unprognostic (2.54e-1)" "potential prognostic unfavorable (8.00e-4)" "unprognostic (3.32e-1)" "unprognostic (1.06e-1)" "unprognostic (3.12e-1)" "unprognostic (5.91e-3)" "unprognostic (1.51e-3)" "unprognostic (1.83e-1)" "unprognostic (2.09e-1)" "unprognostic (3.37e-2)" "unprognostic (9.96e-3)" "unprognostic (7.29e-2)" "unprognostic (7.00e-3)" "unprognostic (2.19e-3)" "unprognostic (1.43e-1)" "unprognostic (7.05e-2)" "unprognostic (2.72e-1)" "unprognostic (1.13e-1)" "unprognostic (1.85e-1)" UPB1 BUP1 ENSG00000100024 "Beta-ureidopropionase 1" Q9UBR1 22 24494107-24528390 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 152.4" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 72.5;Early primary spermatocytes: 38.7;Hepatocytes: 386.8;Neutrophils: 50.9;Oocytes: 221.0;Proximal tubule cells: 253.1" "Cell type enriched" "Detected in some" 4 "pericyte: 49.7" "Cancer enriched" "Detected in some" 4 "Liver Hepatocellular Carcinoma (TCGA): 36.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "basophil: 2.1;neutrophil: 1.9" "Lineage enriched" "Detected in single" 14 "granulocytes: 2.1" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Pancreas - Alpha cells, Skin - Sebaceous gland cells, Testis - Spermatogonia" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA000728, HPA076321" Enhanced NA NA 1700000 "Cluster 35: Neutrophils - Protein binding" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 15: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 88: Proximal tubular cells - Transmembrane transport" "HPA000728: , HPA076321: " "unprognostic (2.51e-2)" "validated prognostic favorable (2.43e-6)" "validated prognostic favorable (1.28e-6)" "validated prognostic favorable (9.73e-5)" "validated prognostic favorable (2.54e-7)" "unprognostic (8.08e-3)" UPF1 "HUPF1, KIAA0221, NORF1, pNORF1, RENT1, smg-2" ENSG00000005007 "UPF1 RNA helicase and ATPase" Q92900 19 18831959-18868230 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Nonsense-mediated mRNA decay" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019587, HPA020857" Approved Supported Nucleoplasm,Cytosol NA NA 5900 "Cluster 24: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 24: Neutrophils - Innate immunity signal integration" 191 Nucleoplasm Cytosol "HPA019587: , HPA020857: " "unprognostic (9.13e-2)" "unprognostic (1.22e-1)" "unprognostic (3.74e-2)" "unprognostic (1.80e-2)" "unprognostic (4.11e-2)" "unprognostic (1.25e-2)" "unprognostic (1.72e-1)" "unprognostic (2.78e-1)" "unprognostic (1.05e-1)" "unprognostic (1.38e-2)" "potential prognostic favorable (1.83e-7)" "unprognostic (1.58e-2)" "unprognostic (1.15e-1)" "unprognostic (1.66e-1)" "unprognostic (1.21e-1)" "unprognostic (5.18e-2)" "unprognostic (1.74e-1)" "unprognostic (1.98e-1)" "unprognostic (3.55e-2)" "unprognostic (1.20e-1)" "unprognostic (3.82e-1)" "unprognostic (7.47e-2)" "unprognostic (2.78e-1)" "unprognostic (1.26e-1)" "unprognostic (7.42e-2)" "unprognostic (9.78e-3)" "potential prognostic unfavorable (2.44e-4)" "unprognostic (9.12e-2)" "unprognostic (1.42e-1)" "unprognostic (1.11e-1)" "unprognostic (7.34e-2)" UPF2 "DKFZP434D222, KIAA1408, RENT2, smg-3" ENSG00000151461 "UPF2 regulator of nonsense mediated mRNA decay" Q9HAU5 10 11920022-12043170 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Nonsense-mediated mRNA decay" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067008 Supported "Vesicles,Primary cilium,Primary cilium tip,Cytosol,Cytoplasmic bodies" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 61: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 82: Dendritic cells - Antigen presentation" 37 Cytosol "Vesicles, Primary cilium, Primary cilium tip, Cytoplasmic bodies" "HPA067008: " "unprognostic (5.27e-2)" "unprognostic (1.77e-2)" "unprognostic (9.98e-2)" "unprognostic (1.06e-1)" "unprognostic (4.35e-1)" "unprognostic (6.81e-2)" "unprognostic (1.69e-2)" "potential prognostic favorable (1.03e-5)" "unprognostic (2.45e-2)" "potential prognostic unfavorable (1.85e-4)" "potential prognostic favorable (2.33e-6)" "unprognostic (2.31e-3)" "unprognostic (5.36e-3)" "potential prognostic unfavorable (3.55e-5)" "unprognostic (4.03e-2)" "unprognostic (2.52e-1)" "unprognostic (7.44e-3)" "unprognostic (1.54e-1)" "unprognostic (8.50e-2)" "unprognostic (1.76e-1)" "unprognostic (1.09e-2)" "unprognostic (2.00e-2)" "unprognostic (9.68e-3)" "unprognostic (3.20e-2)" "unprognostic (8.71e-2)" "unprognostic (6.89e-2)" "unprognostic (1.99e-1)" "unprognostic (1.17e-1)" "unprognostic (4.73e-1)" "unprognostic (1.02e-1)" "unprognostic (1.33e-1)" UPF3A "HUPF3A, RENT3A, UPF3" ENSG00000169062 "UPF3A regulator of nonsense mediated mRNA decay" Q9H1J1 13 114281601-114305817 "Predicted intracellular proteins" "mRNA transport, Nonsense-mediated mRNA decay, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 708.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018325, HPA061316" Approved Supported "Nucleoplasm,Vesicles,Plasma membrane,Primary cilium,Primary cilium tip,Basal body" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 67: Testis - Mixed function" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 14 "Nucleoplasm, Vesicles, Plasma membrane" "Primary cilium, Primary cilium tip, Basal body" "HPA018325: , HPA061316: " "unprognostic (3.38e-2)" "unprognostic (2.97e-1)" "unprognostic (2.69e-1)" "unprognostic (9.27e-2)" "unprognostic (1.27e-1)" "unprognostic (1.30e-1)" "validated prognostic favorable (2.23e-4)" "validated prognostic favorable (9.40e-4)" "unprognostic (5.65e-2)" "unprognostic (3.35e-1)" "potential prognostic favorable (5.46e-5)" "unprognostic (3.89e-3)" "unprognostic (2.50e-2)" "unprognostic (5.57e-3)" "unprognostic (4.39e-2)" "unprognostic (1.87e-1)" "unprognostic (8.63e-2)" "unprognostic (1.03e-1)" "unprognostic (4.62e-2)" "unprognostic (2.80e-1)" "unprognostic (8.21e-2)" "unprognostic (1.19e-2)" "unprognostic (5.24e-2)" "unprognostic (1.37e-2)" "unprognostic (5.02e-1)" "unprognostic (1.52e-1)" "unprognostic (2.45e-2)" "unprognostic (4.07e-1)" "unprognostic (1.89e-1)" "unprognostic (9.32e-2)" "unprognostic (3.16e-1)" UPF3B "HUPF3B, MRX62, MRX82, RENT3B, UPF3BP1, UPF3BP2, UPF3BP3, UPF3X" ENSG00000125351 "UPF3B regulator of nonsense mediated mRNA decay" Q9BZI7 X 119834022-119852998 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "mRNA transport, Nonsense-mediated mRNA decay, Transport" RNA-binding "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 225.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001592, HPA001800, HPA001882" Approved Enhanced Nucleoplasm,Nucleoli,Cytosol No No "Cluster 22: Eosinophils - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 36: Non-specific - mRNA processing" "Cluster 41: Oocytes - Oogenesis" 26 Cytosol "Nucleoplasm, Nucleoli" "HPA001592: , HPA001800: , HPA001882: " "unprognostic (1.95e-1)" "unprognostic (1.50e-1)" "unprognostic (2.75e-1)" "unprognostic (1.76e-1)" "unprognostic (1.14e-2)" "unprognostic (2.40e-1)" "unprognostic (5.06e-2)" "unprognostic (1.26e-1)" "unprognostic (2.72e-1)" "unprognostic (9.85e-3)" "unprognostic (4.18e-3)" "unprognostic (6.41e-2)" "unprognostic (1.08e-2)" "potential prognostic unfavorable (9.86e-8)" "unprognostic (1.97e-2)" "unprognostic (6.58e-2)" "unprognostic (4.07e-3)" "unprognostic (1.30e-3)" "unprognostic (5.14e-2)" "unprognostic (1.49e-1)" "unprognostic (8.51e-2)" "unprognostic (1.37e-1)" "unprognostic (3.21e-3)" "unprognostic (1.84e-3)" "unprognostic (3.63e-1)" "unprognostic (1.96e-1)" "unprognostic (3.53e-3)" "unprognostic (7.37e-2)" "unprognostic (3.01e-1)" "unprognostic (2.27e-1)" "unprognostic (1.57e-1)" UPK1A TSPAN21 ENSG00000105668 "Uroplakin 1A" O00322 19 35666517-35678481 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "urinary bladder: 122.1" "Cell type enhanced" "Detected in some" "Esophageal apical cells: 248.2;Papillary tip epithelial cells: 68.8;Prostatic club cells: 187.1;Prostatic hillock cells: 95.2;Urothelial cells: 588.0" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 38 "Bladder Urothelial Carcinoma (TCGA): 241.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Bladder cancer: 20.7" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA049879 Enhanced NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 69: Urothelial cells - Basic cellular functions" 1 "HPA049879: " "unprognostic (1.97e-3)" "unprognostic (6.94e-2)" "unprognostic (1.95e-1)" "unprognostic (5.99e-2)" "unprognostic (6.26e-2)" "potential prognostic unfavorable (5.00e-4)" "unprognostic (2.39e-1)" "unprognostic (1.35e-1)" "unprognostic (1.15e-1)" "unprognostic (1.93e-2)" "unprognostic (7.32e-2)" "unprognostic (6.56e-2)" "unprognostic (7.17e-2)" UPK1B "TSPAN20, UPK1" ENSG00000114638 "Uroplakin 1B" O75841 3 119173517-119205143 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 31.9;urinary bladder: 82.9" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 87.7;Endometrial luminal cells: 122.6;Ocular epithelial cells: 387.8;Respiratory basal cells: 64.9;Respiratory deuterosomal cells: 191.8;Respiratory secretory cells: 219.5;Urothelial cells: 493.4" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 296.4;Lung Squamous Cell Carcinoma (TCGA): 123.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder cancer: 251.9" "Adipose visceral - Mesothelial cells, Minor Salivary Gland - Minor salivary gland basal cells, Stomach - Gastric mucous cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" "HPA031799, HPA031800" Enhanced NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 33: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 41 "HPA031799: , HPA031800: " "unprognostic (1.23e-1)" "unprognostic (7.45e-3)" "unprognostic (1.54e-1)" "unprognostic (6.13e-2)" "unprognostic (2.65e-1)" "potential prognostic favorable (3.71e-6)" "unprognostic (8.32e-2)" "unprognostic (4.23e-3)" "unprognostic (4.97e-3)" "unprognostic (6.90e-2)" "unprognostic (9.74e-3)" "unprognostic (2.13e-1)" "unprognostic (1.13e-1)" "unprognostic (2.66e-2)" "potential prognostic unfavorable (7.60e-4)" "unprognostic (1.17e-1)" "potential prognostic unfavorable (3.23e-4)" "unprognostic (1.02e-1)" "unprognostic (2.76e-1)" UPK2 "MGC138598, UP2, UPII" ENSG00000110375 "Uroplakin 2" O00526 11 118925164-118958559 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 25 "urinary bladder: 61.6" "Cell type enriched" "Detected in many" 4 "Urothelial cells: 138.8" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in many" 63 "Bladder Urothelial Carcinoma (TCGA): 550.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder cancer: 35.8" "Prostate - Urothelial cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043312, HPA061106" Enhanced NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 69: Urothelial cells - Basic cellular functions" 71 "HPA043312: , HPA061106: " "unprognostic (5.19e-3)" "unprognostic (1.49e-2)" "unprognostic (2.70e-1)" "unprognostic (2.70e-1)" "unprognostic (1.09e-3)" "unprognostic (6.56e-2)" "unprognostic (4.01e-1)" "unprognostic (7.90e-2)" "unprognostic (1.12e-3)" "unprognostic (3.41e-1)" "unprognostic (2.29e-2)" "unprognostic (2.08e-2)" "unprognostic (1.44e-1)" UPK3A UPK3 ENSG00000100373 "Uroplakin 3A" O75631 22 45284949-45295874 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "prostate: 20.9;skeletal muscle: 32.8;urinary bladder: 39.1" "Cell type enriched" "Detected in some" 5 "Urothelial cells: 383.7" "Cell type enhanced" "Detected in single" "central nervous system macrophage: 1.6" "Group enriched" "Detected in many" 7 "Bladder Urothelial Carcinoma (TCGA): 140.3;Prostate Adenocarcinoma (TCGA): 58.4" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "myeloid DC: 86.7" "Group enriched" "Detected in many" 16 "dendritic cells: 86.7;monocytes: 32.2" "Cancer enhanced" "Detected in some" "breast cancer: 7.8;colorectal cancer: 7.4;prostate cancer: 6.3" "Prostate - Prostate glandular cells, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA018407, HPA018415" Enhanced Uncertain "Nuclear membrane,Nuclear bodies" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Breast cancer - Unknown function" "Cluster 69: Urothelial cells - Basic cellular functions" 2 "Nuclear membrane" "Nuclear bodies" "HPA018407: , HPA018415: " "unprognostic (2.37e-1)" "unprognostic (7.03e-2)" "unprognostic (1.88e-2)" "unprognostic (1.18e-2)" "unprognostic (3.51e-2)" "unprognostic (1.74e-1)" "unprognostic (2.15e-2)" "unprognostic (1.88e-2)" "unprognostic (1.22e-2)" "potential prognostic unfavorable (5.72e-4)" "unprognostic (9.16e-3)" "unprognostic (9.14e-2)" "unprognostic (2.22e-1)" "unprognostic (3.08e-1)" "unprognostic (1.69e-1)" "unprognostic (2.62e-1)" "unprognostic (1.74e-2)" "unprognostic (6.51e-2)" "unprognostic (2.58e-1)" UPK3B "FLJ32198, MGC10902, p35, UPIIIb" ENSG00000243566 "Uroplakin 3B" Q9BT76 7 76510525-76516522 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "adipose tissue: 113.3;esophagus: 64.1;lung: 47.7;urinary bladder: 34.1" "Group enriched" "Detected in some" 4 "Alveolar cells type 1: 22.3;Esophageal apical cells: 28.4;Mesothelial cells: 29.9;Papillary tip epithelial cells: 13.9;Urothelial cells: 8.2" "Cell type enriched" "Detected in some" 4 "choroid plexus epithelial cell: 6.4" "Group enriched" "Detected in many" 11 "Bladder Urothelial Carcinoma (TCGA): 51.7;Ovary Serous Cystadenocarcinoma (TCGA): 53.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "ovarian cancer: 49.5" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 1, Minor Salivary Gland - Minor salivary gland basal cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA010506 Approved NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 1 "HPA010506: " "unprognostic (1.04e-3)" "unprognostic (2.74e-1)" "unprognostic (2.66e-2)" "unprognostic (5.30e-2)" "unprognostic (4.10e-3)" "unprognostic (2.46e-1)" "unprognostic (5.50e-2)" "unprognostic (1.62e-1)" "unprognostic (4.95e-2)" "unprognostic (2.40e-1)" "unprognostic (4.48e-3)" "unprognostic (2.19e-2)" "unprognostic (7.50e-3)" "unprognostic (2.45e-2)" "unprognostic (2.99e-2)" "unprognostic (2.19e-2)" UPK3BL1 "UPK3BL, UPLP" ENSG00000267368 "Uroplakin 3B like 1" B0FP48 7 102637025-102642791 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 259.9" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA011403 Supported NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 6: Non-specific - Immune response" "Cluster 61: BICR 18 - Protein kinases" "Cluster 100: Stratified epithelial cells - Barrier functions" "HPA011403: " "unprognostic (8.94e-2)" "unprognostic (3.65e-3)" "unprognostic (4.59e-3)" "unprognostic (8.52e-2)" "unprognostic (3.96e-1)" "unprognostic (1.37e-1)" "unprognostic (5.68e-2)" "unprognostic (9.12e-2)" "unprognostic (3.90e-2)" "potential prognostic unfavorable (2.01e-7)" "unprognostic (1.07e-2)" "unprognostic (1.42e-1)" "unprognostic (2.74e-2)" "unprognostic (1.21e-2)" "unprognostic (1.97e-1)" "unprognostic (1.85e-1)" "unprognostic (1.43e-1)" "unprognostic (2.61e-1)" "unprognostic (2.41e-3)" "unprognostic (2.70e-3)" "unprognostic (2.66e-3)" "unprognostic (2.83e-1)" "unprognostic (7.96e-2)" "unprognostic (1.38e-1)" "unprognostic (3.58e-2)" "unprognostic (3.30e-2)" "unprognostic (2.47e-1)" "unprognostic (2.64e-1)" "unprognostic (2.63e-1)" UPK3BL2 ENSG00000284981 "Uroplakin 3B like 2" E5RIL1 7 102537919-102543696 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Bladder cancer: 2.7;cervical cancer: 3.7;Esophageal cancer: 8.9;head and neck cancer: 6.8" HPA011403 Approved NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 61: BICR 18 - Protein kinases" "HPA011403: " "unprognostic (1.67e-2)" "unprognostic (4.36e-2)" "unprognostic (1.97e-2)" "unprognostic (1.40e-1)" "unprognostic (2.08e-1)" "unprognostic (1.01e-1)" "unprognostic (1.54e-1)" "unprognostic (3.33e-2)" "potential prognostic unfavorable (5.12e-5)" "unprognostic (4.68e-2)" "unprognostic (3.74e-1)" "unprognostic (3.34e-2)" "unprognostic (9.05e-2)" "unprognostic (1.20e-1)" "unprognostic (6.84e-2)" "unprognostic (3.56e-2)" "unprognostic (2.65e-1)" "unprognostic (2.73e-3)" "unprognostic (4.41e-2)" "unprognostic (7.92e-2)" "unprognostic (1.47e-2)" "unprognostic (9.84e-2)" "unprognostic (2.90e-1)" "unprognostic (3.72e-1)" "unprognostic (2.74e-2)" "unprognostic (2.34e-3)" UPP1 "UDRPASE, UP, UPASE, UPP" ENSG00000183696 "Uridine phosphorylase 1" Q16831 7 48088628-48108736 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 42.3" "Cell type enriched" "Detected in many" 4 "Esophageal apical cells: 2390.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 76.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 125.9" "Pituitary gland - Endothelial cells, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA054040, HPA055394" Enhanced Enhanced Nucleoplasm No No "Cluster 42: Non-specific - Vesicular transport" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 84: Apical squamous epithelium - Cornification" 25 Nucleoplasm "HPA054040: , HPA055394: " "potential prognostic unfavorable (1.93e-4)" "unprognostic (2.93e-1)" "unprognostic (9.91e-2)" "unprognostic (1.56e-3)" "unprognostic (3.41e-1)" "unprognostic (5.97e-2)" "potential prognostic unfavorable (8.59e-4)" "unprognostic (6.04e-2)" "unprognostic (8.08e-2)" "unprognostic (3.92e-1)" "unprognostic (7.93e-2)" "unprognostic (3.52e-1)" "unprognostic (2.08e-2)" "unprognostic (1.17e-3)" "unprognostic (1.36e-2)" "validated prognostic unfavorable (4.45e-4)" "validated prognostic unfavorable (9.94e-5)" "unprognostic (6.88e-3)" "potential prognostic unfavorable (5.10e-4)" "unprognostic (3.09e-1)" "unprognostic (3.60e-3)" "unprognostic (1.34e-1)" "potential prognostic unfavorable (1.76e-4)" "unprognostic (2.37e-1)" "unprognostic (8.79e-2)" "unprognostic (1.31e-2)" "unprognostic (1.32e-1)" "unprognostic (2.99e-2)" "unprognostic (6.37e-2)" "unprognostic (3.91e-1)" "unprognostic (1.71e-3)" UPP2 "UDRPASE2, UP2, UPASE2" ENSG00000007001 "Uridine phosphorylase 2" O95045 2 157876702-158136154 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "kidney: 42.7;liver: 22.3" "Cell type enhanced" "Detected in many" "Adipocytes: 210.3;Astrocytes: 138.5;Bergmann glia: 440.8;Brain excitatory neurons: 185.1;Brain inhibitory neurons: 142.8;Loop of henle epithelial cells: 103.3;Oligodendrocyte progenitor cells: 177.7;Pituitary stem cells: 126.2;Proximal tubule cells: 133.1;Salivary acinar cells: 118.0" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Kidney Renal Papillary Cell Carcinoma (TCGA): 1.3;Liver Hepatocellular Carcinoma (TCGA): 5.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA035225, HPA035226" Approved Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 76: Non-specific - Metabolism" "Cluster 51: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 35: Neurons - Synaptic function & neurogenesis" 3 Nucleoplasm "Vesicles, Mitochondria" "HPA035225: , HPA035226: " "unprognostic (1.48e-2)" "unprognostic (2.23e-2)" "unprognostic (1.46e-2)" "unprognostic (6.15e-2)" "unprognostic (2.11e-3)" UPRT "DKFZp781E1243, FUR1, MGC23937, RP11-311P8.3" ENSG00000094841 "Uracil phosphoribosyltransferase homolog" Q96BW1 X 75156388-75304885 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 105.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000805 Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 36: Non-specific - mRNA processing" "Cluster 84: Apical squamous epithelium - Cornification" 13 Nucleoplasm Vesicles "HPA000805: " "unprognostic (9.90e-2)" "unprognostic (7.83e-3)" "unprognostic (1.29e-1)" "unprognostic (2.31e-1)" "unprognostic (2.19e-1)" "unprognostic (1.54e-1)" "unprognostic (2.68e-1)" "unprognostic (1.48e-1)" "unprognostic (9.86e-3)" "unprognostic (4.66e-2)" "potential prognostic favorable (1.35e-6)" "unprognostic (3.69e-2)" "unprognostic (4.56e-1)" "unprognostic (6.00e-2)" "unprognostic (1.98e-1)" "unprognostic (2.53e-3)" "unprognostic (1.08e-1)" "unprognostic (2.63e-1)" "unprognostic (2.72e-1)" "unprognostic (2.29e-1)" "unprognostic (1.95e-1)" "unprognostic (1.38e-2)" "unprognostic (9.22e-2)" "unprognostic (2.92e-1)" "unprognostic (5.33e-2)" "unprognostic (2.15e-2)" "unprognostic (1.46e-2)" "unprognostic (2.80e-1)" "unprognostic (2.26e-2)" "unprognostic (2.28e-1)" "unprognostic (1.59e-1)" UQCC1 "BFZB, C20orf44, CBP3, FLJ10850, UQCC" ENSG00000101019 "Ubiquinol-cytochrome c reductase complex assembly factor 1" Q9NVA1 20 35302566-35412031 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 247.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034875 Approved Approved "Nucleoplasm,Plasma membrane,Actin filaments" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 55: Myocytes - Oxidative muscle function" 27 "Plasma membrane" "Nucleoplasm, Actin filaments" "HPA034875: " "unprognostic (1.22e-1)" "unprognostic (2.59e-2)" "unprognostic (8.85e-2)" "unprognostic (3.52e-1)" "unprognostic (1.51e-1)" "unprognostic (2.11e-1)" "unprognostic (7.81e-2)" "unprognostic (6.20e-2)" "unprognostic (6.74e-2)" "potential prognostic favorable (1.58e-4)" "unprognostic (2.05e-1)" "unprognostic (1.74e-2)" "unprognostic (2.45e-3)" "unprognostic (4.15e-3)" "unprognostic (1.23e-1)" "unprognostic (1.59e-1)" "unprognostic (1.81e-2)" "unprognostic (7.80e-2)" "unprognostic (3.25e-1)" "unprognostic (2.64e-1)" "unprognostic (2.49e-3)" "unprognostic (2.91e-1)" "unprognostic (1.49e-3)" "unprognostic (1.03e-1)" "unprognostic (2.87e-1)" "unprognostic (2.63e-1)" "unprognostic (1.11e-1)" "unprognostic (8.28e-2)" "unprognostic (1.33e-1)" UQCC2 "bA6B20.2, C6orf125, Cbp6, M19, MGC14833, MNF1" ENSG00000137288 "Ubiquinol-cytochrome c reductase complex assembly factor 2" Q9BRT2 6 33694293-33711727 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 333.3;Late primary spermatocytes: 431.2;Late spermatids: 1702.3;Megakaryocytes: 364.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039111 Uncertain Supported "Nuclear bodies,Mitochondria" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 28: Non-specific - Nuclear processes" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 17 Mitochondria "Nuclear bodies" "HPA039111: " "unprognostic (3.07e-2)" "unprognostic (9.32e-2)" "unprognostic (7.01e-2)" "unprognostic (2.61e-1)" "unprognostic (2.67e-1)" "unprognostic (2.93e-1)" "unprognostic (1.49e-3)" "unprognostic (1.35e-2)" "unprognostic (1.19e-2)" "potential prognostic unfavorable (5.26e-5)" "unprognostic (4.93e-2)" "unprognostic (2.01e-1)" "unprognostic (1.62e-2)" "unprognostic (2.29e-3)" "unprognostic (3.53e-2)" "unprognostic (6.20e-2)" "unprognostic (1.05e-1)" "unprognostic (2.61e-3)" "unprognostic (3.62e-2)" "unprognostic (1.45e-1)" "unprognostic (3.52e-2)" "unprognostic (2.77e-1)" "unprognostic (2.21e-2)" "unprognostic (3.67e-2)" "unprognostic (5.81e-2)" "unprognostic (6.24e-2)" "unprognostic (1.02e-1)" "unprognostic (2.13e-1)" "unprognostic (1.24e-1)" UQCC3 "C11orf83, UNQ655" ENSG00000204922 "Ubiquinol-cytochrome c reductase complex assembly factor 3" Q6UW78 11 62670273-62673686 "Disease related genes, Essential proteins, Human disease related genes, Predicted membrane proteins" "ATP synthesis" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Enterocytes: 182.7;Esophageal apical cells: 292.7;Esophageal basal cells: 183.8;Esophageal suprabasal cells: 247.0;Gastric progenitor cells: 220.4;Parietal cells: 180.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046851 Approved Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 24: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 2 "Nucleoplasm, Mitochondria" Cytosol "HPA046851: " "unprognostic (1.37e-1)" "unprognostic (1.47e-1)" "unprognostic (4.05e-2)" "unprognostic (5.34e-2)" "unprognostic (2.44e-1)" "unprognostic (8.12e-2)" "unprognostic (6.03e-2)" "unprognostic (1.56e-1)" "potential prognostic unfavorable (8.26e-5)" "unprognostic (2.25e-1)" "unprognostic (3.16e-2)" "unprognostic (4.02e-1)" "potential prognostic unfavorable (4.33e-5)" "unprognostic (2.83e-2)" "unprognostic (1.66e-2)" "unprognostic (1.26e-1)" "unprognostic (6.14e-2)" "unprognostic (2.76e-2)" "unprognostic (1.09e-1)" "unprognostic (7.26e-2)" "unprognostic (1.38e-1)" "unprognostic (1.15e-1)" "unprognostic (2.15e-1)" "unprognostic (1.75e-1)" "unprognostic (2.07e-2)" "unprognostic (5.60e-2)" "unprognostic (1.55e-1)" "unprognostic (1.38e-1)" "unprognostic (2.07e-2)" UQCR10 "HSPC051, QCR9, UCCR7.2, UCRC" ENSG00000184076 "Ubiquinol-cytochrome c reductase, complex III subunit X" Q9UDW1 22 29767369-29770413 "Metabolic proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 1502.1;Late primary spermatocytes: 1219.4;Parietal cells: 2809.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 66: Non-specific - Mitochondria" "Cluster 97: Non-specific - Cellular respiration" 3 "unprognostic (3.25e-1)" "unprognostic (2.06e-1)" "unprognostic (6.41e-2)" "potential prognostic favorable (3.25e-4)" "unprognostic (9.30e-2)" "unprognostic (8.03e-3)" "unprognostic (2.50e-1)" "unprognostic (1.77e-1)" "unprognostic (1.66e-3)" "unprognostic (2.20e-2)" "unprognostic (6.89e-2)" "unprognostic (3.24e-2)" "potential prognostic favorable (6.98e-4)" "unprognostic (2.64e-2)" "potential prognostic unfavorable (3.19e-4)" "unprognostic (4.56e-1)" "unprognostic (7.35e-2)" "unprognostic (2.74e-2)" "unprognostic (1.18e-2)" "unprognostic (6.95e-2)" "unprognostic (2.75e-1)" "unprognostic (4.87e-2)" "unprognostic (2.46e-1)" "unprognostic (1.33e-2)" "unprognostic (9.68e-2)" "unprognostic (2.75e-1)" "unprognostic (2.82e-1)" "unprognostic (5.44e-2)" "unprognostic (1.79e-1)" "unprognostic (2.47e-1)" "unprognostic (1.64e-1)" UQCR11 "QCR10, UQCR" ENSG00000127540 "Ubiquinol-cytochrome c reductase, complex III subunit XI" O14957 19 1597169-1605473 "Essential proteins, Metabolic proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 292.4" "Cell type enhanced" "Detected in many" "Colonocytes: 1421.0;Enterocytes: 1550.9;Hepatocytes: 1831.2;Parietal cells: 2498.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 52: Non-specific - Cellular respiration" "Cluster 45: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" "unprognostic (1.21e-1)" "unprognostic (2.25e-1)" "unprognostic (1.06e-1)" "potential prognostic favorable (6.24e-4)" "unprognostic (1.27e-2)" "unprognostic (1.03e-1)" "unprognostic (1.46e-1)" "unprognostic (3.96e-1)" "unprognostic (1.21e-1)" "potential prognostic unfavorable (5.67e-4)" "unprognostic (8.02e-2)" "unprognostic (3.37e-2)" "unprognostic (7.59e-3)" "unprognostic (9.91e-2)" "unprognostic (3.73e-2)" "unprognostic (3.14e-1)" "unprognostic (2.95e-2)" "unprognostic (8.34e-2)" "unprognostic (1.67e-1)" "unprognostic (3.89e-1)" "unprognostic (1.04e-1)" "unprognostic (3.57e-3)" "unprognostic (1.60e-1)" "unprognostic (9.64e-2)" "unprognostic (1.29e-1)" "unprognostic (2.79e-1)" "unprognostic (1.80e-1)" "unprognostic (1.73e-1)" "unprognostic (1.12e-1)" "unprognostic (1.37e-1)" "unprognostic (1.53e-1)" UQCRB "QCR7, QP-C, UQBP, UQCR6" ENSG00000156467 "Ubiquinol-cytochrome c reductase binding protein" P14927 8 96222947-96235546 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 1224.5" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 2003.4;Esophageal suprabasal cells: 1889.4;Kupffer cells: 2063.1;Parietal cells: 4364.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043060 Approved NA NA 11000 "Cluster 31: T-cells - T-cell receptor" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 40: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 35 "HPA043060: " "unprognostic (2.56e-2)" "unprognostic (7.28e-2)" "unprognostic (1.60e-1)" "unprognostic (1.21e-1)" "unprognostic (1.78e-1)" "unprognostic (2.33e-2)" "unprognostic (8.85e-2)" "unprognostic (4.74e-2)" "unprognostic (3.74e-3)" "unprognostic (1.09e-3)" "validated prognostic favorable (3.00e-5)" "validated prognostic favorable (8.28e-5)" "unprognostic (1.34e-1)" "unprognostic (2.40e-1)" "unprognostic (9.29e-3)" "unprognostic (2.45e-3)" "unprognostic (8.28e-2)" "unprognostic (3.76e-1)" "unprognostic (3.96e-1)" "unprognostic (5.54e-2)" "unprognostic (2.59e-2)" "unprognostic (6.75e-2)" "potential prognostic unfavorable (9.87e-6)" "unprognostic (1.64e-1)" "unprognostic (2.83e-1)" "unprognostic (5.79e-3)" "unprognostic (2.23e-2)" "unprognostic (3.74e-1)" "unprognostic (1.87e-1)" "unprognostic (2.48e-2)" "unprognostic (3.33e-1)" UQCRC1 "D3S3191, QCR1, UQCR1" ENSG00000010256 "Ubiquinol-cytochrome c reductase core protein 1" P31930 3 48599002-48610976 "Disease related genes, Enzymes, Essential proteins, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Neuropathy, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 604.8;skeletal muscle: 718.0;tongue: 825.7" "Cell type enhanced" "Detected in all" "Colonocytes: 545.6;Enterocytes: 496.5;Esophageal basal cells: 469.2;Late spermatids: 538.3;Parietal cells: 601.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002815, HPA003525, CAB033782" Enhanced Supported Mitochondria NA NA 180000 "Cluster 29: Non-specific - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 45: Non-specific - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 97: Non-specific - Cellular respiration" 56 Mitochondria "CAB033782: , HPA002815: , HPA003525: " "unprognostic (1.34e-2)" "unprognostic (8.66e-3)" "potential prognostic unfavorable (1.42e-4)" "unprognostic (1.94e-2)" "unprognostic (9.63e-3)" "unprognostic (1.03e-1)" "unprognostic (3.40e-1)" "unprognostic (1.56e-1)" "unprognostic (1.52e-2)" "unprognostic (5.68e-2)" "potential prognostic favorable (7.18e-4)" "unprognostic (2.40e-1)" "potential prognostic favorable (2.09e-4)" "unprognostic (3.84e-2)" "unprognostic (1.30e-2)" "unprognostic (5.49e-3)" "unprognostic (7.62e-2)" "unprognostic (3.60e-1)" "unprognostic (2.28e-1)" "unprognostic (6.74e-2)" "unprognostic (4.53e-2)" "unprognostic (2.35e-1)" "unprognostic (4.00e-2)" "unprognostic (1.31e-2)" "unprognostic (1.56e-1)" "unprognostic (2.44e-1)" "unprognostic (2.55e-3)" "unprognostic (8.95e-2)" "unprognostic (1.76e-1)" "unprognostic (3.12e-1)" "unprognostic (4.58e-1)" UQCRC2 "QCR2, UQCR2" ENSG00000140740 "Ubiquinol-cytochrome c reductase core protein 2" P22695 16 21953288-21983660 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 871.3" "Cell type enhanced" "Detected in all" "Parietal cells: 351.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007998, HPA019146" Enhanced Enhanced Mitochondria NA NA 160000 "Cluster 33: Non-specific - ATP binding" "Cluster 52: Non-specific - Cellular respiration" "Cluster 23: Choroid plexus - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 97: Non-specific - Cellular respiration" 51 Mitochondria "HPA007998: , HPA019146: " "unprognostic (3.20e-3)" "unprognostic (2.83e-3)" "unprognostic (1.72e-1)" "unprognostic (2.80e-1)" "unprognostic (7.37e-2)" "unprognostic (2.60e-3)" "unprognostic (4.66e-3)" "potential prognostic favorable (7.82e-4)" "unprognostic (1.24e-1)" "unprognostic (2.18e-1)" "potential prognostic favorable (3.51e-7)" "unprognostic (2.47e-1)" "unprognostic (1.86e-3)" "unprognostic (1.35e-1)" "unprognostic (2.09e-1)" "unprognostic (2.83e-2)" "unprognostic (1.66e-1)" "unprognostic (5.64e-2)" "unprognostic (1.97e-1)" "unprognostic (3.95e-3)" "unprognostic (8.16e-2)" "unprognostic (3.14e-2)" "unprognostic (7.78e-2)" "unprognostic (5.91e-2)" "unprognostic (1.87e-2)" "unprognostic (1.05e-1)" "unprognostic (2.61e-1)" "unprognostic (4.50e-1)" "unprognostic (1.28e-2)" "unprognostic (3.90e-3)" "unprognostic (3.63e-1)" UQCRFS1 "RIP1, RIS1, RISP, UQCR5" ENSG00000169021 "Ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1" P47985 19 29205320-29213151 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" Translocase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 216.9;tongue: 267.1" "Cell type enhanced" "Detected in many" "Gastric progenitor cells: 1098.4;Late primary spermatocytes: 467.0;Parietal cells: 641.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041863, HPA050339" Enhanced Approved Mitochondria NA NA 25000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 52: Non-specific - Cellular respiration" "Cluster 23: Choroid plexus - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 58 Mitochondria "HPA041863: , HPA050339: " "unprognostic (3.41e-2)" "unprognostic (9.96e-3)" "unprognostic (2.44e-2)" "potential prognostic favorable (3.67e-4)" "potential prognostic favorable (1.97e-4)" "unprognostic (3.73e-3)" "unprognostic (2.36e-1)" "unprognostic (1.19e-1)" "unprognostic (4.94e-2)" "unprognostic (1.26e-1)" "potential prognostic favorable (1.55e-6)" "unprognostic (1.47e-1)" "potential prognostic favorable (7.51e-4)" "unprognostic (3.64e-2)" "unprognostic (3.92e-2)" "unprognostic (4.52e-2)" "unprognostic (6.69e-2)" "unprognostic (2.13e-2)" "unprognostic (5.25e-2)" "unprognostic (4.24e-2)" "unprognostic (2.93e-2)" "unprognostic (1.18e-1)" "unprognostic (2.27e-1)" "unprognostic (3.31e-1)" "unprognostic (3.28e-2)" "unprognostic (1.73e-1)" "unprognostic (5.16e-2)" "unprognostic (1.86e-1)" "unprognostic (1.43e-1)" "unprognostic (6.16e-3)" "unprognostic (8.70e-2)" UQCRH "QCR6, UQCR8" ENSG00000173660 "Ubiquinol-cytochrome c reductase hinge protein" P07919 1 46303698-46316776 "Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 1943.8;Esophageal basal cells: 1665.2;Esophageal suprabasal cells: 2173.1;Gastric progenitor cells: 1666.2;Megakaryocytes: 2509.7;Parietal cells: 3254.7;Platelets: 1633.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" HPA042574 Supported NA NA "Cluster 18: Non-specific - Translation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 23: Choroid plexus - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 97: Non-specific - Cellular respiration" 12 "HPA042574: " "unprognostic (1.81e-2)" "unprognostic (1.11e-2)" "unprognostic (7.48e-2)" "unprognostic (1.92e-2)" "unprognostic (1.60e-2)" "unprognostic (1.22e-1)" "unprognostic (6.40e-2)" "unprognostic (1.07e-2)" "unprognostic (1.30e-3)" "unprognostic (3.67e-2)" "unprognostic (2.00e-3)" "unprognostic (2.79e-1)" "unprognostic (2.10e-1)" "validated prognostic unfavorable (6.03e-6)" "validated prognostic unfavorable (1.49e-7)" "potential prognostic unfavorable (9.83e-4)" "unprognostic (4.81e-3)" "unprognostic (1.29e-1)" "unprognostic (2.21e-1)" "unprognostic (3.08e-1)" "unprognostic (1.84e-1)" "unprognostic (8.10e-2)" "unprognostic (4.35e-1)" "unprognostic (7.09e-3)" "unprognostic (1.32e-1)" "unprognostic (1.56e-1)" "unprognostic (1.78e-2)" "unprognostic (3.32e-3)" "unprognostic (1.73e-1)" "unprognostic (7.94e-2)" "unprognostic (2.13e-1)" UQCRHL ENSG00000233954 "Ubiquinol-cytochrome c reductase hinge protein like" A0A096LP55 1 15807169-15809348 "Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "heart muscle: 15.7" "Cell type enhanced" "Detected in many" "Endometrial secretory cells: 10.7;Esophageal apical cells: 16.5;Esophageal basal cells: 14.8;Esophageal suprabasal cells: 19.0;Megakaryocytes: 18.5" "Cell type enhanced" "Detected in many" "astrocyte: 6.9;Bergmann glia: 8.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Testis - Sertoli cells" HPA042574 Approved NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 48: Non-specific - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 85: Squamous epithelial cells - Keratinization" "HPA042574: " "unprognostic (2.45e-2)" "unprognostic (5.56e-3)" "unprognostic (1.26e-1)" "unprognostic (5.51e-3)" "unprognostic (1.86e-1)" "unprognostic (3.05e-2)" "unprognostic (2.68e-2)" "unprognostic (1.45e-2)" "unprognostic (3.83e-1)" UQCRQ "QCR8, QP-C, UQCR7" ENSG00000164405 "Ubiquinol-cytochrome c reductase complex III subunit VII" O14949 5 132866630-132868847 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1218.1" "Cell type enhanced" "Detected in many" "Colonocytes: 1930.9;Enterocytes: 2130.8;Esophageal apical cells: 1841.0;Esophageal suprabasal cells: 1828.0;Hepatocytes: 5654.0;Parietal cells: 8150.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046693, HPA053323" Approved Enhanced Mitochondria NA NA 41000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 52: Non-specific - Cellular respiration" "Cluster 27: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 97: Non-specific - Cellular respiration" 25 Mitochondria "HPA046693: , HPA053323: " "unprognostic (2.77e-1)" "unprognostic (4.86e-2)" "unprognostic (1.58e-1)" "unprognostic (1.66e-2)" "unprognostic (7.13e-3)" "unprognostic (7.55e-3)" "unprognostic (6.38e-2)" "unprognostic (5.99e-2)" "unprognostic (5.06e-3)" "potential prognostic unfavorable (8.72e-5)" "unprognostic (9.72e-2)" "potential prognostic unfavorable (1.21e-4)" "unprognostic (4.62e-2)" "unprognostic (1.63e-1)" "unprognostic (2.50e-3)" "unprognostic (1.39e-3)" "unprognostic (3.11e-1)" "unprognostic (1.59e-1)" "unprognostic (1.32e-1)" "unprognostic (2.83e-1)" "unprognostic (2.56e-1)" "unprognostic (3.89e-1)" "unprognostic (3.06e-1)" "unprognostic (3.14e-1)" "unprognostic (4.10e-1)" "unprognostic (1.02e-2)" "unprognostic (7.54e-2)" "unprognostic (4.16e-2)" "unprognostic (1.38e-1)" "unprognostic (1.85e-1)" "unprognostic (1.43e-1)" URAD PRHOXNB ENSG00000183463 "Ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase" A6NGE7 13 27977717-27988693 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Purine metabolism" "Decarboxylase, Lyase" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 14 "intestine: 22.6" "Cell type enhanced" "Detected in some" "Colonocytes: 58.5;Enteric stem cells: 55.9;Enteric transient amplifying cells: 69.7;Enterocytes: 166.0;Goblet cells: 101.7;Neuroendocrine cells: 23.5;Paneth cells: 46.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Colon Adenocarcinoma (TCGA): 7.5;Rectum Adenocarcinoma (TCGA): 2.9" "Region enriched" "Detected in single" 4 "cerebellum: 1.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "colorectal cancer: 2.9;liver cancer: 1.3" "Colon - Colon enterocytes, Testis - Early spermatids, Testis - Late spermatids" "Region enhanced" "Detected in many" "cerebral cortex: 6.8" "Low region specificity" "Detected in many" HPA038972 Uncertain NA NA "Cluster 77: Intestine - Digestion" "Cluster 35: Non-specific - DNA binding" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 1: Enterocytes - Absorption and Digestion" "HPA038972: " "unprognostic (8.05e-2)" "unprognostic (3.30e-2)" "unprognostic (2.77e-3)" "unprognostic (9.83e-2)" URB1 "C21orf108, KIAA0539, NPA1" ENSG00000142207 "URB1 ribosome biogenesis homolog" O60287 21 32311018-32393012 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 136.8;Prostatic glandular cells: 120.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018334 Supported Supported "Nucleoli fibrillar center" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 44: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 51: Secretory epithelial cells - Mixed function" 20 "Nucleoli fibrillar center" "HPA018334: " "unprognostic (1.21e-1)" "unprognostic (2.48e-2)" "unprognostic (4.30e-1)" "potential prognostic unfavorable (3.28e-4)" "unprognostic (3.77e-1)" "unprognostic (1.75e-1)" "unprognostic (1.57e-1)" "unprognostic (1.76e-1)" "unprognostic (5.39e-2)" "unprognostic (1.67e-1)" "unprognostic (1.09e-2)" "unprognostic (7.62e-2)" "unprognostic (9.08e-2)" "unprognostic (2.68e-3)" "potential prognostic unfavorable (6.39e-4)" "unprognostic (5.44e-2)" "unprognostic (1.08e-1)" "unprognostic (1.54e-1)" "unprognostic (2.97e-2)" "unprognostic (3.51e-3)" "unprognostic (2.75e-1)" "unprognostic (1.03e-1)" "unprognostic (1.36e-1)" "unprognostic (2.17e-1)" "unprognostic (2.00e-2)" "unprognostic (6.78e-3)" "unprognostic (3.23e-1)" "unprognostic (2.55e-1)" "unprognostic (3.51e-1)" "unprognostic (1.50e-2)" "unprognostic (1.68e-1)" URB2 "KIAA0133, NET10, NPA2" ENSG00000135763 "URB2 ribosome biogenesis homolog" Q14146 1 229626247-229660200 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Corticotrophs: 33.0;Erythrocyte progenitors: 30.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Pituitary gland - Corticotropes, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008902, HPA046788" Uncertain Enhanced Nucleoli NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 39: Testis - Nuclear processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 13 Nucleoli "HPA008902: , HPA046788: " "unprognostic (3.56e-2)" "unprognostic (1.15e-1)" "unprognostic (3.21e-1)" "unprognostic (1.82e-3)" "unprognostic (1.28e-2)" "unprognostic (4.23e-2)" "unprognostic (1.64e-1)" "unprognostic (5.54e-3)" "unprognostic (2.94e-1)" "unprognostic (5.80e-3)" "unprognostic (1.31e-1)" "unprognostic (5.78e-2)" "unprognostic (4.46e-3)" "unprognostic (7.09e-3)" "unprognostic (2.30e-3)" "unprognostic (1.21e-2)" "potential prognostic unfavorable (1.04e-4)" "unprognostic (1.06e-1)" "unprognostic (3.10e-2)" "unprognostic (4.63e-1)" "unprognostic (1.98e-1)" "unprognostic (1.76e-1)" "unprognostic (4.34e-2)" "unprognostic (2.22e-2)" "unprognostic (8.06e-3)" "unprognostic (1.70e-1)" "unprognostic (4.82e-2)" "unprognostic (1.48e-1)" "unprognostic (4.94e-1)" "unprognostic (1.22e-2)" "unprognostic (5.17e-2)" URGCP "DKFZp666G166, DKFZp686O0457, FLJ20654, KIAA1507, URG4" ENSG00000106608 "Upregulator of cell proliferation" Q8TCY9 7 43875894-43926411 "Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 116.9;Brain inhibitory neurons: 115.8;Choroid plexus epithelial cells: 201.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019879, HPA020134, HPA029468" Approved Supported Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 24: Non-specific - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 22: Non-specific - Basic cellular functions" 1 Cytosol "HPA019879: , HPA020134: , HPA029468: " "unprognostic (5.32e-3)" "unprognostic (1.77e-1)" "unprognostic (2.60e-2)" "potential prognostic unfavorable (3.71e-5)" "unprognostic (2.41e-1)" "unprognostic (6.52e-2)" "unprognostic (1.27e-2)" "unprognostic (2.05e-1)" "unprognostic (7.49e-2)" "unprognostic (5.46e-2)" "potential prognostic favorable (4.68e-4)" "unprognostic (6.02e-3)" "potential prognostic favorable (4.17e-5)" "unprognostic (1.40e-1)" "unprognostic (1.36e-2)" "unprognostic (2.64e-2)" "unprognostic (1.63e-2)" "unprognostic (2.09e-1)" "unprognostic (4.78e-3)" "unprognostic (1.28e-1)" "unprognostic (4.96e-2)" "unprognostic (1.15e-2)" "unprognostic (1.84e-1)" "unprognostic (3.06e-1)" "unprognostic (1.99e-1)" "unprognostic (3.11e-1)" "unprognostic (3.51e-1)" "unprognostic (1.11e-1)" "unprognostic (9.83e-2)" "unprognostic (8.15e-2)" "unprognostic (9.98e-2)" URGCP-MRPS24 ENSG00000270617 "URGCP-MRPS24 readthrough" 7 43866558-43906589 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 1.7;Cholangiocytes: 3.9;Endometrial glandular cells: 2.2;Endometrial luminal cells: 2.6;Endometrial secretory cells: 7.5;Endometrial stromal cells: 2.4;Hepatocytes: 2.2;Parietal cells: 1.8;Retinal ganglion cells: 3.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 67: Non-specific - Unknown function" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" "unprognostic (3.12e-1)" "unprognostic (8.33e-3)" "potential prognostic unfavorable (4.07e-4)" "unprognostic (1.19e-1)" "unprognostic (2.86e-2)" "unprognostic (9.90e-2)" "unprognostic (1.86e-1)" URI1 "C19orf2, FLJ10575, NNX3, PPP1R19, RMP, URI" ENSG00000105176 "URI1 prefoldin like chaperone" O94763 19 29923644-30016612 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Protein phosphatase inhibitor, Repressor" Oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 477.7;Late spermatids: 625.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071709 Approved Supported Nucleoplasm,Cytosol Yes No "Cluster 22: Eosinophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 87 Nucleoplasm Cytosol "HPA071709: " "unprognostic (2.49e-1)" "unprognostic (2.46e-1)" "unprognostic (1.61e-1)" "unprognostic (1.17e-2)" "unprognostic (1.87e-1)" "unprognostic (3.96e-2)" "unprognostic (1.05e-1)" "unprognostic (2.14e-1)" "potential prognostic unfavorable (9.11e-4)" "potential prognostic favorable (5.53e-4)" "unprognostic (1.39e-2)" "unprognostic (2.14e-1)" "potential prognostic unfavorable (1.26e-4)" "unprognostic (1.14e-1)" "unprognostic (1.49e-1)" "unprognostic (4.51e-2)" "unprognostic (1.23e-2)" "potential prognostic unfavorable (1.29e-4)" "unprognostic (5.21e-2)" "unprognostic (9.64e-2)" "unprognostic (1.73e-1)" "unprognostic (2.29e-1)" "potential prognostic favorable (9.96e-6)" "unprognostic (1.66e-1)" "unprognostic (5.90e-3)" "unprognostic (1.77e-1)" "unprognostic (2.51e-1)" "unprognostic (1.99e-1)" "unprognostic (6.90e-2)" URM1 "C9orf74, MGC2668" ENSG00000167118 "Ubiquitin related modifier 1" Q9BTM9 9 128371361-128392016 "Essential proteins, Predicted intracellular proteins" "tRNA processing, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053645, HPA065160" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 15: Non-specific - Protein processing" 6 Vesicles Nucleoplasm "HPA053645: , HPA065160: " "unprognostic (1.48e-1)" "unprognostic (2.47e-2)" "unprognostic (2.52e-2)" "unprognostic (6.65e-2)" "unprognostic (3.43e-2)" "unprognostic (2.42e-2)" "unprognostic (2.19e-1)" "unprognostic (1.42e-1)" "unprognostic (1.18e-1)" "unprognostic (4.21e-1)" "unprognostic (5.94e-3)" "unprognostic (8.58e-2)" "potential prognostic favorable (3.85e-6)" "potential prognostic unfavorable (3.53e-4)" "unprognostic (1.01e-3)" "unprognostic (7.89e-3)" "unprognostic (3.98e-2)" "unprognostic (8.41e-2)" "unprognostic (3.98e-3)" "unprognostic (4.68e-2)" "unprognostic (4.13e-2)" "unprognostic (6.14e-2)" "unprognostic (8.45e-2)" "unprognostic (5.20e-2)" "unprognostic (2.04e-1)" "unprognostic (8.29e-2)" "unprognostic (4.20e-1)" "unprognostic (5.70e-3)" "unprognostic (4.76e-1)" "unprognostic (1.76e-1)" "unprognostic (3.03e-2)" UROC1 "FLJ31300, HMFN0320" ENSG00000159650 "Urocanate hydratase 1" Q96N76 3 126481166-126517773 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Histidine metabolism" Lyase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 396 "liver: 112.6" "Group enriched" "Detected in some" 6 "Ependymal cells: 15.9;Hepatocytes: 62.1" "Cell type enriched" "Detected in some" 8 "ependymal cell: 20.8" "Cancer enriched" "Detected in single" 93 "Liver Hepatocellular Carcinoma (TCGA): 15.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes, Lung - Respiratory ciliated cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA069863 Enhanced NA NA 940000 "Cluster 53: Liver - Plasma proteins" "Cluster 35: RS4;11 - Unknown function" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 1 "HPA069863: " "potential prognostic favorable (4.67e-4)" "unprognostic (1.83e-2)" UROD ENSG00000126088 "Uroporphyrinogen decarboxylase" P06132 1 45010950-45015575 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Heme biosynthesis, Porphyrin biosynthesis" "Decarboxylase, Lyase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 350.4;Erythrocytes: 140.1;Megakaryocytes: 426.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027468, HPA028668, HPA030350" Uncertain Supported Nucleoplasm,Cytosol NA NA 2400000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 47: Leukemia - Hemostasis" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 7 "Nucleoplasm, Cytosol" "HPA027468: , HPA028668: , HPA030350: " "unprognostic (1.32e-2)" "unprognostic (2.06e-1)" "unprognostic (1.40e-2)" "unprognostic (6.80e-2)" "unprognostic (3.98e-2)" "unprognostic (5.18e-2)" "unprognostic (1.53e-1)" "unprognostic (1.63e-2)" "unprognostic (2.59e-2)" "unprognostic (7.04e-2)" "potential prognostic favorable (1.39e-5)" "unprognostic (1.80e-2)" "unprognostic (2.53e-2)" "potential prognostic unfavorable (1.79e-6)" "unprognostic (4.05e-2)" "unprognostic (4.26e-2)" "unprognostic (1.95e-2)" "unprognostic (2.69e-1)" "unprognostic (2.86e-1)" "unprognostic (1.14e-1)" "unprognostic (6.14e-2)" "unprognostic (2.45e-1)" "unprognostic (1.22e-1)" "unprognostic (4.46e-1)" "unprognostic (2.48e-2)" "unprognostic (2.35e-1)" "unprognostic (6.47e-3)" "unprognostic (5.18e-2)" "unprognostic (3.61e-1)" "unprognostic (6.29e-2)" "unprognostic (1.90e-1)" UROS ENSG00000188690 "Uroporphyrinogen III synthase" P10746 10 125784980-125823258 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Heme biosynthesis, Porphyrin biosynthesis" Lyase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 234.9;Late spermatids: 188.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044038 Approved Approved Nucleoplasm,Cytosol NA NA 91000 "Cluster 33: Non-specific - ATP binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 33: Neurons - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 1 Nucleoplasm Cytosol "HPA044038: " "unprognostic (2.39e-2)" "unprognostic (2.13e-1)" "unprognostic (1.77e-1)" "unprognostic (1.45e-1)" "unprognostic (1.74e-1)" "unprognostic (1.88e-1)" "unprognostic (4.08e-1)" "potential prognostic favorable (4.65e-8)" "unprognostic (3.10e-2)" "unprognostic (3.96e-2)" "unprognostic (3.61e-1)" "unprognostic (1.35e-3)" "unprognostic (3.11e-2)" "unprognostic (1.81e-1)" "unprognostic (5.62e-2)" "unprognostic (2.76e-1)" "unprognostic (2.26e-2)" "unprognostic (9.78e-2)" "unprognostic (3.14e-2)" "unprognostic (1.18e-2)" "unprognostic (3.85e-3)" "unprognostic (3.22e-2)" "unprognostic (2.31e-1)" "unprognostic (1.39e-2)" "unprognostic (1.40e-2)" "unprognostic (1.33e-1)" "unprognostic (1.27e-1)" "unprognostic (7.62e-2)" "unprognostic (2.20e-1)" "unprognostic (1.57e-1)" "unprognostic (8.00e-3)" USB1 "C16orf57, FLJ13154, HVSL1, Mpn1" ENSG00000103005 "U6 snRNA biogenesis phosphodiesterase 1" Q9BQ65 16 57999546-58021618 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Hydrolase, Lyase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 74.2;Megakaryocytes: 61.8;Neutrophils: 136.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041791, HPA059854" Approved Supported Nucleoplasm NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 24: Neutrophils - Innate immunity signal integration" 18 Nucleoplasm "HPA041791: , HPA059854: " "unprognostic (1.03e-1)" "unprognostic (1.01e-1)" "unprognostic (1.15e-3)" "unprognostic (8.66e-2)" "unprognostic (1.43e-2)" "unprognostic (1.21e-1)" "unprognostic (4.69e-2)" "unprognostic (3.10e-3)" "unprognostic (8.73e-2)" "unprognostic (1.02e-3)" "unprognostic (4.67e-2)" "unprognostic (9.33e-2)" "potential prognostic unfavorable (6.55e-7)" "unprognostic (2.50e-2)" "unprognostic (1.52e-2)" "unprognostic (9.45e-2)" "unprognostic (4.71e-2)" "unprognostic (8.83e-3)" "unprognostic (1.43e-1)" "unprognostic (5.43e-2)" "unprognostic (1.79e-3)" "unprognostic (2.00e-1)" "unprognostic (1.57e-2)" "unprognostic (2.29e-2)" "unprognostic (1.10e-1)" "unprognostic (7.76e-2)" "unprognostic (2.61e-1)" "unprognostic (1.20e-1)" "unprognostic (2.00e-1)" USE1 "D12, MDS032, p31, SLT1" ENSG00000053501 "Unconventional SNARE in the ER 1" Q9NZ43 19 17215346-17219829 "Essential proteins, Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 226.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026851, HPA047562" Approved NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 24: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 23: Non-specific - Transcription" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 63 "HPA026851: , HPA047562: " "unprognostic (5.27e-3)" "unprognostic (7.49e-2)" "unprognostic (4.48e-1)" "unprognostic (2.09e-2)" "unprognostic (3.32e-2)" "unprognostic (1.13e-1)" "unprognostic (1.40e-1)" "unprognostic (1.08e-1)" "unprognostic (1.15e-1)" "unprognostic (2.57e-2)" "unprognostic (1.64e-2)" "unprognostic (1.29e-1)" "unprognostic (2.97e-1)" "unprognostic (1.52e-1)" "unprognostic (4.78e-3)" "unprognostic (1.48e-2)" "unprognostic (3.18e-2)" "unprognostic (3.02e-1)" "unprognostic (1.48e-1)" "unprognostic (6.14e-2)" "unprognostic (7.11e-2)" "unprognostic (1.23e-1)" "unprognostic (3.29e-1)" "unprognostic (2.97e-1)" "unprognostic (1.75e-2)" "unprognostic (1.05e-2)" "unprognostic (1.16e-1)" "unprognostic (4.54e-3)" "unprognostic (3.17e-1)" "unprognostic (1.95e-1)" "unprognostic (3.51e-1)" USF1 "bHLHb11, MLTFI, UEF" ENSG00000158773 "Upstream transcription factor 1" P22415 1 161039251-161045977 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001480, HPA036233, HPA036535, HPA068527" Supported Enhanced Nucleoplasm NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 14: Neurons - Synaptic function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 34 Nucleoplasm "CAB001480: , HPA036233: , HPA036535: , HPA068527: " "unprognostic (6.98e-2)" "unprognostic (3.45e-2)" "unprognostic (1.65e-1)" "unprognostic (1.49e-2)" "unprognostic (7.82e-2)" "unprognostic (2.67e-1)" "unprognostic (7.51e-2)" "potential prognostic favorable (8.44e-4)" "unprognostic (7.58e-3)" "unprognostic (5.58e-2)" "unprognostic (4.34e-2)" "unprognostic (7.52e-3)" "unprognostic (1.72e-1)" "potential prognostic unfavorable (4.11e-4)" "unprognostic (2.82e-1)" "unprognostic (7.91e-2)" "unprognostic (2.26e-2)" "unprognostic (2.70e-1)" "unprognostic (2.34e-1)" "unprognostic (4.75e-2)" "unprognostic (2.08e-3)" "unprognostic (5.42e-2)" "unprognostic (8.53e-2)" "unprognostic (2.80e-2)" "unprognostic (1.51e-1)" "unprognostic (1.48e-1)" "unprognostic (3.39e-2)" "unprognostic (1.56e-2)" "unprognostic (1.28e-1)" "unprognostic (1.89e-1)" "unprognostic (2.48e-1)" USF2 "bHLHb12, FIP" ENSG00000105698 "Upstream transcription factor 2, c-fos interacting" Q15853 19 35268962-35279821 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Platelets: 401.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029764, HPA046567" Supported Nucleoplasm,Vesicles NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 8 Nucleoplasm Vesicles "HPA029764: , HPA046567: " "unprognostic (3.38e-2)" "unprognostic (1.65e-2)" "unprognostic (4.02e-1)" "unprognostic (1.50e-2)" "unprognostic (1.46e-1)" "unprognostic (5.20e-3)" "unprognostic (3.95e-2)" "unprognostic (2.66e-1)" "unprognostic (1.85e-1)" "unprognostic (1.90e-1)" "unprognostic (1.98e-2)" "unprognostic (1.73e-1)" "unprognostic (1.99e-2)" "unprognostic (2.63e-1)" "unprognostic (5.44e-2)" "unprognostic (3.28e-1)" "unprognostic (1.15e-2)" "unprognostic (1.60e-1)" "unprognostic (2.31e-1)" "unprognostic (1.76e-1)" "unprognostic (9.99e-2)" "unprognostic (2.43e-3)" "unprognostic (1.97e-1)" "unprognostic (2.23e-2)" "unprognostic (2.82e-1)" "unprognostic (1.56e-1)" "unprognostic (1.47e-1)" "unprognostic (3.56e-2)" "unprognostic (2.76e-1)" "unprognostic (4.08e-1)" "unprognostic (1.92e-1)" USF3 KIAA2018 ENSG00000176542 "Upstream transcription factor family member 3" Q68DE3 3 113648385-113696646 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 158.3;Neutrophils: 191.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029243, HPA029245" Uncertain Uncertain Nucleoplasm,Nucleoli,Centrosome NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 24: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 1 "Nucleoplasm, Nucleoli" Centrosome "HPA029243: , HPA029245: " "unprognostic (1.24e-2)" "unprognostic (3.17e-3)" "unprognostic (3.28e-1)" "unprognostic (1.82e-1)" "unprognostic (2.39e-1)" "unprognostic (1.18e-1)" "unprognostic (2.74e-1)" "unprognostic (1.71e-2)" "unprognostic (5.76e-2)" "unprognostic (1.68e-3)" "unprognostic (1.20e-1)" "unprognostic (5.75e-2)" "unprognostic (1.50e-1)" "unprognostic (1.27e-2)" "unprognostic (1.39e-1)" "unprognostic (1.00e-1)" "unprognostic (3.79e-2)" "unprognostic (2.96e-1)" "unprognostic (1.52e-1)" "unprognostic (4.52e-1)" "unprognostic (9.89e-3)" "unprognostic (1.90e-1)" "unprognostic (3.50e-1)" "unprognostic (1.52e-1)" "unprognostic (2.89e-1)" "unprognostic (3.80e-1)" "unprognostic (1.28e-1)" "unprognostic (9.31e-2)" "unprognostic (2.89e-1)" USH1C "AIE-75, DFNB18, harmonin, NY-CO-37, NY-CO-38, PDZ-73, PDZ73, PDZD7C" ENSG00000006611 "USH1 protein network component harmonin" Q9Y6N9 11 17493895-17544416 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Hearing" "Cancer-related genes, Deafness, Non-syndromic deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 92.0;kidney: 50.5" "Cell type enhanced" "Detected in some" "Colonocytes: 219.8;Enteric stem cells: 114.3;Enteric transient amplifying cells: 142.3;Enterocytes: 448.1;Epididymal efferent duct absorptive cells: 88.7;Foveolar cells: 63.1;Goblet cells: 114.4;Müller glia: 192.8;Neuroendocrine cells: 88.3;Pancreatic islet cells: 69.2;Paneth cells: 85.1;Proximal tubule cells: 141.2;Tuft cells: 196.0" "Cell type enhanced" "Detected in many" "astrocyte: 43.6;hippocampal CA4: 30.0;oligodendrocyte: 68.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 76.6;Gastric cancer: 40.3" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Cholangiocytes, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB013690, HPA027398, HPA027492, HPA028033" Enhanced Enhanced Cytosol No NA "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 9 Cytosol "CAB013690: , HPA027398: , HPA027492: , HPA028033: " "unprognostic (4.28e-1)" "unprognostic (1.15e-1)" "unprognostic (1.07e-1)" "unprognostic (3.93e-1)" "unprognostic (1.12e-3)" "unprognostic (2.70e-1)" "potential prognostic favorable (6.96e-9)" "unprognostic (1.07e-1)" "potential prognostic favorable (1.55e-4)" "potential prognostic unfavorable (9.34e-5)" "unprognostic (1.19e-1)" "unprognostic (1.15e-1)" "unprognostic (1.48e-1)" "unprognostic (9.45e-2)" "unprognostic (7.62e-2)" "unprognostic (6.08e-2)" "unprognostic (4.11e-1)" "unprognostic (4.99e-2)" "unprognostic (1.79e-1)" "unprognostic (2.46e-2)" "unprognostic (1.83e-1)" "unprognostic (2.36e-2)" USH1G "ANKS4A, FLJ33924, Sans" ENSG00000182040 "USH1 protein network component sans" Q495M9 17 74916083-74923256 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hearing "Deafness, Disease variant, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 7.5;skin 1: 2.7" "Cell type enhanced" "Detected in some" "Early spermatids: 11.2;Epididymal principal cells: 3.3;Esophageal apical cells: 10.3;Esophageal suprabasal cells: 7.6;Late spermatids: 41.4;Müller glia: 12.3;Suprabasal keratinocytes: 4.8" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Head and Neck Squamous Cell Carcinoma (TCGA): 3.5;Lung Squamous Cell Carcinoma (TCGA): 2.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 3.6;Gallbladder cancer: 3.8;head and neck cancer: 2.9" "Prostate - Urothelial cells, Testis - Late spermatids" "Region enriched" "Detected in single" 12 "olfactory bulb: 9.9" "Low region specificity" "Detected in single" HPA024360 Uncertain Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 21 Vesicles "Nucleoplasm, Cytosol" "HPA024360: " "unprognostic (5.25e-2)" "unprognostic (1.11e-2)" "unprognostic (2.69e-1)" "unprognostic (1.26e-2)" "unprognostic (2.92e-2)" USH2A "RP39, USH2" ENSG00000042781 Usherin O75445 1 215622891-216423448 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Hearing, Sensory transduction, Vision" "Deafness, Disease variant, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 21 "liver: 6.5;retina: 17.8" "Group enriched" "Detected in many" 6 "Cone photoreceptor cells: 1146.8;Rod photoreceptor cells: 1572.5" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA045176 Approved "Acrosome,Equatorial segment,Mid piece,Principal piece,End piece" "Intracellular and membrane" Other NA NA "Cluster 42: Retina - Visual perception" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 11: Neuronal - Sensory perception" "Cluster 79: Photoreceptor cells - Phototransduction" "Acrosome, Equatorial segment, Mid piece, Principal piece" "End piece" "HPA045176: " "unprognostic (1.13e-1)" USHBP1 "AIEBP, FLJ38709, MCC2" ENSG00000130307 "USH1 protein network component harmonin binding protein 1" Q8N6Y0 19 17249171-17282786 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 12.8" "Cell type enhanced" "Detected in many" "Adipocytes: 48.7;Cardiomyocytes: 185.8;Epicardial cells: 61.4;Vascular endothelial cells: 27.0" "Cell type enhanced" "Detected in all" "endothelial cell: 40.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Colon - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052471 Uncertain Approved Nucleoli NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 15: Non-specific - Transcription" "Cluster 34: Testis cancer - Unknown function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 182 Nucleoli "HPA052471: " "unprognostic (3.03e-1)" "unprognostic (6.96e-2)" "unprognostic (8.84e-3)" "potential prognostic unfavorable (7.67e-4)" "unprognostic (6.40e-3)" "unprognostic (3.01e-2)" "unprognostic (7.32e-2)" "unprognostic (1.36e-1)" "unprognostic (1.23e-1)" "potential prognostic favorable (9.56e-4)" "unprognostic (1.95e-3)" "unprognostic (4.95e-2)" "unprognostic (1.17e-1)" "potential prognostic favorable (4.38e-4)" "unprognostic (5.92e-2)" "unprognostic (9.27e-2)" "unprognostic (1.05e-1)" "unprognostic (1.00e-1)" "unprognostic (2.41e-1)" "unprognostic (1.86e-1)" "unprognostic (1.02e-2)" "unprognostic (2.87e-2)" "unprognostic (1.92e-1)" "unprognostic (6.84e-2)" "unprognostic (2.42e-2)" "potential prognostic unfavorable (2.57e-4)" "unprognostic (7.30e-2)" "unprognostic (1.74e-1)" "unprognostic (7.79e-2)" USO1 "p115, TAP, VDP" ENSG00000138768 "USO1 vesicle transport factor" O60763 4 75724577-75814286 "Essential proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 207.7" "Cell type enhanced" "Detected in all" "Myonuclei: 638.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010108, HPA038282, HPA038283" Supported Supported "Nucleoli fibrillar center,Golgi apparatus" NA NA 98000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 20 "Golgi apparatus" "Nucleoli fibrillar center" "CAB010108: , HPA038282: , HPA038283: " "unprognostic (7.70e-3)" "unprognostic (4.93e-3)" "unprognostic (1.48e-1)" "potential prognostic unfavorable (8.70e-5)" "unprognostic (2.28e-2)" "unprognostic (1.62e-2)" "unprognostic (8.18e-2)" "potential prognostic unfavorable (9.60e-4)" "unprognostic (4.59e-1)" "unprognostic (1.15e-2)" "potential prognostic favorable (3.23e-8)" "unprognostic (2.21e-2)" "unprognostic (1.35e-1)" "unprognostic (2.45e-3)" "unprognostic (4.50e-2)" "unprognostic (9.80e-2)" "unprognostic (8.24e-3)" "unprognostic (2.10e-2)" "unprognostic (1.27e-1)" "unprognostic (9.32e-2)" "unprognostic (1.16e-1)" "unprognostic (3.06e-2)" "unprognostic (6.70e-2)" "unprognostic (2.20e-2)" "unprognostic (5.74e-2)" "unprognostic (7.89e-2)" "unprognostic (7.66e-2)" "unprognostic (5.12e-2)" "unprognostic (4.28e-1)" "unprognostic (3.33e-2)" "unprognostic (1.73e-2)" USP1 ENSG00000162607 "Ubiquitin specific peptidase 1" O94782 1 62436297-62451804 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 211.5;Early primary spermatocytes: 257.7;Late primary spermatocytes: 352.0;Monocyte progenitors: 178.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028387, HPA028440" Approved Supported Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 27: Non-specific - Cell proliferation" 40 Nucleoplasm "HPA028387: , HPA028440: " "unprognostic (1.52e-1)" "unprognostic (6.56e-2)" "unprognostic (1.36e-2)" "unprognostic (2.27e-1)" "unprognostic (9.98e-3)" "unprognostic (2.13e-1)" "unprognostic (2.75e-1)" "unprognostic (1.49e-1)" "unprognostic (8.38e-2)" "potential prognostic unfavorable (2.42e-6)" "potential prognostic favorable (1.04e-5)" "unprognostic (2.24e-3)" "unprognostic (6.67e-2)" "validated prognostic unfavorable (2.78e-5)" "validated prognostic unfavorable (2.20e-4)" "unprognostic (6.33e-3)" "unprognostic (1.77e-2)" "unprognostic (2.68e-1)" "unprognostic (1.31e-2)" "unprognostic (1.41e-1)" "unprognostic (4.70e-2)" "potential prognostic unfavorable (6.98e-4)" "unprognostic (2.69e-1)" "unprognostic (4.30e-2)" "unprognostic (4.81e-3)" "unprognostic (3.47e-1)" "unprognostic (5.05e-2)" "unprognostic (6.28e-2)" "unprognostic (7.65e-2)" "unprognostic (3.49e-2)" "unprognostic (1.32e-1)" USP10 "KIAA0190, UBPO" ENSG00000103194 "Ubiquitin specific peptidase 10" Q14694 16 84699986-84779922 "Enzymes, Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Autophagy, DNA damage, DNA repair, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 577.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "neutrophil: 747.5" "Lineage enriched" "Detected in all" 5 "granulocytes: 747.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006731, HPA006749" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 87 Cytosol Nucleoplasm "HPA006731: , HPA006749: " "unprognostic (5.89e-3)" "unprognostic (2.59e-2)" "unprognostic (1.79e-1)" "unprognostic (3.16e-1)" "unprognostic (1.28e-1)" "unprognostic (1.05e-1)" "unprognostic (1.14e-1)" "unprognostic (7.15e-2)" "unprognostic (1.08e-2)" "unprognostic (2.36e-1)" "potential prognostic favorable (1.57e-5)" "unprognostic (2.29e-1)" "unprognostic (8.75e-3)" "unprognostic (1.03e-2)" "unprognostic (4.33e-3)" "unprognostic (8.81e-2)" "unprognostic (3.92e-3)" "unprognostic (3.20e-2)" "unprognostic (6.21e-3)" "unprognostic (3.02e-1)" "unprognostic (3.48e-2)" "unprognostic (6.47e-3)" "unprognostic (7.90e-3)" "unprognostic (3.64e-2)" "unprognostic (1.23e-2)" "unprognostic (2.93e-2)" "unprognostic (4.86e-2)" "unprognostic (2.36e-1)" "unprognostic (6.18e-2)" "unprognostic (1.34e-1)" "unprognostic (3.99e-1)" USP11 UHX1 ENSG00000102226 "Ubiquitin specific peptidase 11" P51784 X 47232866-47248328 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 169.4" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003103, HPA037536" Enhanced Supported Supported Nucleoplasm,Cytosol NA NA 8100 "Cluster 5: Non-specific - Cell proliferation" "Cluster 65: Brain - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 36: Non-specific - mRNA processing" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 109 Nucleoplasm Cytosol "HPA003103: , HPA037536: " "unprognostic (1.32e-1)" "unprognostic (1.57e-1)" "unprognostic (1.99e-1)" "unprognostic (2.83e-2)" "unprognostic (2.88e-1)" "unprognostic (2.02e-1)" "unprognostic (1.31e-1)" "unprognostic (3.91e-3)" "unprognostic (1.38e-1)" "unprognostic (1.97e-1)" "validated prognostic favorable (1.04e-4)" "validated prognostic favorable (1.04e-4)" "unprognostic (1.30e-1)" "unprognostic (4.96e-3)" "unprognostic (6.78e-2)" "unprognostic (3.11e-1)" "unprognostic (1.47e-1)" "unprognostic (9.47e-2)" "potential prognostic favorable (2.63e-4)" "unprognostic (1.87e-1)" "unprognostic (1.25e-1)" "unprognostic (6.89e-3)" "unprognostic (9.08e-2)" "unprognostic (1.24e-1)" "unprognostic (1.21e-1)" "unprognostic (4.61e-2)" "unprognostic (4.31e-2)" "unprognostic (3.22e-2)" "unprognostic (1.51e-1)" "unprognostic (7.78e-2)" "unprognostic (7.20e-2)" USP12 USP12L1 ENSG00000152484 "Ubiquitin specific peptidase 12" O75317 13 27066156-27171811 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epicardial cells: 382.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007288, HPA059492" Uncertain Approved Nucleoplasm NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 21 Nucleoplasm "HPA007288: , HPA059492: " "unprognostic (4.85e-3)" "unprognostic (4.29e-3)" "unprognostic (1.47e-1)" "unprognostic (3.14e-3)" "unprognostic (1.06e-1)" "unprognostic (1.07e-1)" "unprognostic (2.51e-1)" "unprognostic (3.15e-1)" "unprognostic (4.67e-2)" "unprognostic (7.35e-2)" "validated prognostic favorable (4.32e-6)" "validated prognostic favorable (3.03e-4)" "unprognostic (1.67e-2)" "unprognostic (4.56e-2)" "unprognostic (1.57e-1)" "unprognostic (1.26e-1)" "unprognostic (1.76e-2)" "unprognostic (9.77e-3)" "unprognostic (9.63e-2)" "unprognostic (7.98e-2)" "potential prognostic unfavorable (7.64e-4)" "unprognostic (1.72e-1)" "unprognostic (2.85e-2)" "unprognostic (1.56e-2)" "unprognostic (4.21e-2)" "unprognostic (7.86e-2)" "unprognostic (1.23e-1)" "unprognostic (4.94e-2)" "unprognostic (1.67e-1)" "unprognostic (1.90e-2)" "unprognostic (9.31e-2)" USP13 IsoT-3 ENSG00000058056 "Ubiquitin specific peptidase 13" Q92995 3 179653032-179804366 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Autophagy, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 9 "heart muscle: 39.8;skeletal muscle: 99.1;tongue: 101.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 65.3;Cardiomyocytes: 57.3;Myonuclei: 108.5;Oligodendrocyte progenitor cells: 59.4;Oligodendrocytes: 57.2;Thymic myoid cells: 106.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 15.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Kidney - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004827 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 1: T-cells - Unknown function" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 45 "Nucleoplasm, Cytosol" "HPA004827: " "unprognostic (1.47e-1)" "unprognostic (1.78e-2)" "unprognostic (1.02e-1)" "unprognostic (8.71e-2)" "unprognostic (5.64e-2)" "unprognostic (1.34e-1)" "unprognostic (6.27e-2)" "unprognostic (3.52e-2)" "unprognostic (1.10e-1)" "unprognostic (3.14e-3)" "unprognostic (8.94e-2)" "unprognostic (3.45e-1)" "unprognostic (1.36e-3)" "validated prognostic unfavorable (4.11e-4)" "validated prognostic unfavorable (9.49e-5)" "unprognostic (5.91e-2)" "unprognostic (7.60e-3)" "unprognostic (2.43e-1)" "unprognostic (1.66e-1)" "unprognostic (2.40e-2)" "unprognostic (9.96e-2)" "unprognostic (4.27e-1)" "unprognostic (3.22e-1)" "unprognostic (2.85e-1)" "unprognostic (1.55e-2)" "unprognostic (1.14e-1)" "unprognostic (3.82e-3)" "unprognostic (4.73e-3)" "unprognostic (1.23e-1)" "unprognostic (2.71e-1)" "unprognostic (8.66e-3)" USP14 "TGT, Ubp6" ENSG00000101557 "Ubiquitin specific peptidase 14" P54578 18 158383-214629 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001308 Approved Supported "Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA 4400000 "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 94 "Plasma membrane, Cytosol" "Endoplasmic reticulum" "HPA001308: " "unprognostic (3.79e-3)" "unprognostic (3.80e-1)" "unprognostic (1.44e-2)" "unprognostic (3.95e-2)" "unprognostic (1.03e-1)" "unprognostic (6.55e-2)" "unprognostic (1.89e-1)" "unprognostic (4.51e-2)" "potential prognostic unfavorable (1.61e-4)" "unprognostic (4.59e-2)" "potential prognostic favorable (3.82e-7)" "unprognostic (2.32e-1)" "unprognostic (2.38e-1)" "validated prognostic unfavorable (4.69e-4)" "validated prognostic unfavorable (1.61e-5)" "potential prognostic unfavorable (1.41e-4)" "unprognostic (2.35e-1)" "unprognostic (7.60e-2)" "unprognostic (1.55e-1)" "unprognostic (1.43e-2)" "unprognostic (3.38e-1)" "unprognostic (6.90e-2)" "unprognostic (1.20e-3)" "unprognostic (9.14e-2)" "unprognostic (1.61e-1)" "unprognostic (9.66e-2)" "unprognostic (2.09e-1)" "unprognostic (2.51e-1)" "unprognostic (3.50e-1)" "unprognostic (2.28e-1)" "unprognostic (2.42e-1)" USP15 "KIAA0529, UNPH4" ENSG00000135655 "Ubiquitin specific peptidase 15" Q9Y4E8 12 62260338-62417431 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 166.2" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 1325.1;Neutrophils: 4247.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 300.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 300.7" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006237, HPA006428, HPA071014" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 320000 "Cluster 35: Neutrophils - Protein binding" "Cluster 15: Bone marrow - Innate immune response" "Cluster 5: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 24: Neutrophils - Innate immunity signal integration" 103 Cytosol "Nucleoplasm, Nuclear bodies" "HPA006237: , HPA006428: , HPA071014: " "unprognostic (1.88e-1)" "unprognostic (2.55e-2)" "unprognostic (2.99e-1)" "unprognostic (1.24e-1)" "unprognostic (2.29e-1)" "unprognostic (1.92e-1)" "unprognostic (2.28e-1)" "unprognostic (1.40e-2)" "unprognostic (2.69e-1)" "potential prognostic unfavorable (1.41e-5)" "unprognostic (7.43e-2)" "unprognostic (7.79e-2)" "unprognostic (2.27e-1)" "unprognostic (3.35e-3)" "unprognostic (1.51e-1)" "unprognostic (2.98e-1)" "unprognostic (2.89e-3)" "unprognostic (1.66e-1)" "unprognostic (1.30e-1)" "unprognostic (6.34e-2)" "unprognostic (2.78e-1)" "unprognostic (9.89e-2)" "unprognostic (1.25e-3)" "unprognostic (3.07e-1)" "unprognostic (5.25e-2)" "unprognostic (3.70e-2)" "unprognostic (3.12e-3)" "unprognostic (3.44e-1)" "unprognostic (2.92e-1)" "unprognostic (3.09e-2)" "unprognostic (1.54e-1)" USP16 Ubp-M ENSG00000156256 "Ubiquitin specific peptidase 16" Q9Y5T5 21 29024629-29054488 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, Chromatin regulator, Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 549.6;Late primary spermatocytes: 371.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021140 Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 13 "Nucleoplasm, Cytosol" "HPA021140: " "unprognostic (5.68e-2)" "unprognostic (2.53e-2)" "unprognostic (9.66e-2)" "unprognostic (3.55e-2)" "unprognostic (2.03e-1)" "unprognostic (9.29e-2)" "unprognostic (3.26e-2)" "unprognostic (1.23e-1)" "unprognostic (6.42e-3)" "unprognostic (1.89e-2)" "potential prognostic favorable (3.04e-5)" "unprognostic (1.26e-3)" "unprognostic (1.85e-1)" "unprognostic (6.62e-2)" "unprognostic (2.01e-1)" "unprognostic (4.03e-1)" "unprognostic (4.12e-2)" "unprognostic (1.21e-1)" "unprognostic (1.71e-2)" "unprognostic (4.82e-2)" "unprognostic (4.31e-1)" "unprognostic (2.07e-1)" "unprognostic (2.72e-1)" "unprognostic (8.19e-2)" "unprognostic (2.84e-2)" "unprognostic (2.49e-1)" "unprognostic (1.94e-1)" "unprognostic (2.94e-1)" "unprognostic (1.35e-2)" "unprognostic (1.51e-2)" "unprognostic (1.06e-1)" USP17L1 USP17L1P ENSG00000230549 "Ubiquitin specific peptidase 17 like family member 1" Q7RTZ2 8 7332387-7333979 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain NA NA "Cluster 24: Neurons - Mixed function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "HPA045642: " USP17L10 ENSG00000231396 "Ubiquitin specific peptidase 17 like family member 10" C9JJH3 4 9210657-9212249 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain NA NA "HPA045642: " USP17L11 ENSG00000233136 "Ubiquitin specific peptidase 17 like family member 11" C9JVI0 4 9215405-9216997 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain NA NA "Cluster 53: Neurons - Mixed function" "Cluster 54: Non-specific - Transcription" "HPA045642: " USP17L12 ENSG00000227551 "Ubiquitin specific peptidase 17 like family member 12" C9JPN9 4 9220152-9221744 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain NA NA "HPA045642: " USP17L13 ENSG00000232399 "Ubiquitin specific peptidase 17 like family member 13" C9JLJ4 4 9224896-9226488 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain NA NA "HPA045642: " USP17L15 ENSG00000223569 "Ubiquitin specific peptidase 17 like family member 15" C9J2P7 4 9234385-9236046 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain NA NA "Cluster 24: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "HPA045642: " "unprognostic (6.32e-3)" USP17L17 ENSG00000249104 "Ubiquitin specific peptidase 17 like family member 17" D6RBQ6 4 9243879-9245471 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain NA NA "HPA045642: " USP17L18 ENSG00000250844 "Ubiquitin specific peptidase 17 like family member 18" D6R9N7 4 9248630-9250222 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain NA NA "HPA045642: " USP17L19 ENSG00000248920 "Ubiquitin specific peptidase 17 like family member 19" D6RCP7 4 9253378-9254970 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain NA NA "HPA045642: " USP17L2 DUB3 ENSG00000223443 "Ubiquitin specific peptidase 17 like family member 2" Q6R6M4 8 12136435-12138849 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain NA NA "Cluster 24: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 13 "HPA045642: " USP17L20 ENSG00000250745 "Ubiquitin specific peptidase 17 like family member 20" D6RJB6 4 9258124-9259716 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain NA NA "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 54: Non-specific - Transcription" "HPA045642: " USP17L21 ENSG00000249811 "Ubiquitin specific peptidase 17 like family member 21" D6R901 4 9262872-9264464 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain NA NA "HPA045642: " USP17L22 ENSG00000248933 "Ubiquitin specific peptidase 17 like family member 22" D6RA61 4 9267619-9269211 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain NA NA "Cluster 24: Neurons - Mixed function" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" "HPA045642: " USP17L23 ENSG00000250913 "Ubiquitin specific peptidase 17 like family member 23" D6RBM5 4 9272364-9272914 "Enzymes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 53: Squamous epithelial cells - Keratinization" USP17L24 ENSG00000232264 "Ubiquitin specific peptidase 17 like family member 24" Q0WX57 4 9325165-9326757 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain NA NA "Cluster 24: Neurons - Mixed function" "HPA045642: " USP17L25 ENSG00000230430 "Ubiquitin specific peptidase 17 like family member 25" Q0WX57 4 9329911-9331503 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain NA NA "Cluster 24: Neurons - Mixed function" "HPA045642: " USP17L26 ENSG00000229579 "Ubiquitin specific peptidase 17 like family member 26" Q0WX57 4 9334658-9336250 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain NA NA "Cluster 24: Neurons - Mixed function" "HPA045642: " USP17L27 ENSG00000235780 "Ubiquitin specific peptidase 17 like family member 27" Q0WX57 4 9344148-9345740 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain NA NA "Cluster 24: Neurons - Mixed function" "HPA045642: " USP17L28 ENSG00000231051 "Ubiquitin specific peptidase 17 like family member 28" Q0WX57 4 9348893-9350485 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain NA NA "Cluster 24: Neurons - Mixed function" "HPA045642: " USP17L29 ENSG00000231637 "Ubiquitin specific peptidase 17 like family member 29" Q0WX57 4 9353638-9355230 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain NA NA "Cluster 24: Neurons - Mixed function" "HPA045642: " USP17L3 "USP17B, USP17F" ENSG00000225327 "Ubiquitin specific peptidase 17 like family member 3" A6NCW0 8 7976393-7977985 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain NA NA "HPA045642: " USP17L30 ENSG00000228856 "Ubiquitin specific peptidase 17 like family member 30" Q0WX57 4 9363129-9364721 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain NA NA "Cluster 24: Neurons - Mixed function" "HPA045642: " USP17L4 ENSG00000236125 "Ubiquitin specific peptidase 17 like family member 4" A6NCW7 8 7337115-7338707 "Enzymes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain NA NA "Cluster 9: Non-specific - Receptor signaling" "HPA045642: " USP17L5 ENSG00000227140 "Ubiquitin specific peptidase 17 like family member 5" A8MUK1 4 9339403-9340995 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain NA NA "HPA045642: " USP17L7 ENSG00000226430 "Ubiquitin specific peptidase 17 like family member 7" P0C7H9 8 12132417-12134099 "Enzymes, Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain NA NA "Cluster 28: Astrocytes - Homeostasis & neuron support" "HPA045642: " USP17L8 ENSG00000237038 "Ubiquitin specific peptidase 17 like family member 8" P0C7I0 8 7971661-7973253 "Enzymes, Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain NA NA "HPA045642: " USP18 ENSG00000184979 "Ubiquitin specific peptidase 18" Q9UMW8 22 18150118-18177397 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 21.3;Oocytes: 59.9" "Cell type enhanced" "Detected in many" "endothelial cell: 14.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Skin - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044768 Uncertain Supported Vesicles,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 108: Fibroblasts - ECM organization" 16 Cytosol Vesicles "HPA044768: " "unprognostic (8.18e-2)" "unprognostic (2.56e-1)" "unprognostic (5.16e-1)" "unprognostic (3.22e-3)" "unprognostic (1.35e-1)" "unprognostic (1.74e-2)" "unprognostic (1.04e-1)" "unprognostic (2.20e-1)" "unprognostic (2.37e-1)" "unprognostic (4.22e-2)" "unprognostic (2.07e-2)" "unprognostic (1.87e-1)" "unprognostic (1.57e-1)" "unprognostic (5.32e-3)" "unprognostic (8.39e-2)" "unprognostic (8.95e-3)" "unprognostic (2.28e-2)" "unprognostic (1.27e-1)" "unprognostic (2.06e-2)" "unprognostic (1.72e-2)" "unprognostic (1.99e-1)" "unprognostic (7.95e-2)" "unprognostic (2.50e-2)" "unprognostic (1.46e-1)" "unprognostic (9.27e-2)" "unprognostic (4.77e-2)" "unprognostic (1.68e-1)" "unprognostic (3.53e-1)" "unprognostic (4.70e-3)" "unprognostic (3.07e-2)" "unprognostic (2.05e-3)" USP19 "KIAA0891, ZMYND9" ENSG00000172046 "Ubiquitin specific peptidase 19" O94966 3 49108046-49120938 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" 27 "unprognostic (1.34e-1)" "unprognostic (2.16e-2)" "unprognostic (7.45e-2)" "unprognostic (3.66e-2)" "unprognostic (4.76e-2)" "unprognostic (2.46e-1)" "unprognostic (1.10e-1)" "unprognostic (1.20e-1)" "unprognostic (7.99e-3)" "potential prognostic unfavorable (7.84e-4)" "validated prognostic favorable (1.80e-6)" "validated prognostic favorable (7.39e-4)" "unprognostic (1.04e-3)" "unprognostic (3.01e-2)" "unprognostic (9.26e-2)" "unprognostic (7.67e-3)" "unprognostic (2.28e-1)" "unprognostic (2.14e-1)" "unprognostic (3.53e-2)" "unprognostic (7.68e-2)" "unprognostic (1.37e-1)" "unprognostic (8.63e-2)" "unprognostic (1.88e-1)" "unprognostic (3.43e-1)" "unprognostic (3.77e-2)" "unprognostic (1.18e-1)" "unprognostic (1.24e-1)" "unprognostic (4.15e-1)" "unprognostic (2.01e-1)" "unprognostic (5.28e-2)" "unprognostic (1.03e-2)" USP2 UBP41 ENSG00000036672 "Ubiquitin specific peptidase 2" O75604 11 119355215-119381711 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Myogenesis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 157.6" "Group enriched" "Detected in many" 5 "Early spermatids: 576.2;Late spermatids: 1912.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Myeloma: 14.9" "Heart muscle - Cardiomyocytes, Skin - Keratinocyte (granular), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006777, HPA007222" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 16: Non-specific - Transcription" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 120 Cytosol "Plasma membrane" "HPA006777: , HPA007222: " "unprognostic (6.42e-2)" "unprognostic (5.66e-2)" "unprognostic (1.09e-1)" "unprognostic (1.55e-2)" "unprognostic (9.39e-2)" "unprognostic (1.11e-1)" "unprognostic (2.39e-1)" "unprognostic (1.48e-1)" "unprognostic (1.22e-3)" "unprognostic (2.27e-1)" "validated prognostic favorable (1.68e-8)" "validated prognostic favorable (2.13e-5)" "unprognostic (9.30e-2)" "unprognostic (2.57e-1)" "unprognostic (3.29e-3)" "unprognostic (5.64e-2)" "unprognostic (1.11e-1)" "unprognostic (5.59e-2)" "unprognostic (2.15e-1)" "unprognostic (3.00e-3)" "unprognostic (2.01e-1)" "unprognostic (2.75e-3)" "unprognostic (6.66e-2)" "unprognostic (2.03e-2)" "unprognostic (1.81e-1)" "unprognostic (9.43e-2)" "unprognostic (9.61e-3)" "unprognostic (1.58e-1)" "unprognostic (2.20e-1)" "unprognostic (8.22e-3)" "unprognostic (1.08e-1)" USP20 KIAA1003 ENSG00000136878 "Ubiquitin specific peptidase 20" Q9Y2K6 9 129834698-129881828 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Endocytosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Platelets: 94.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006287, HPA007008" Uncertain Supported Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 49: Non-specific - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" 63 "Nucleoplasm, Plasma membrane, Cytosol" "HPA006287: , HPA007008: " "unprognostic (1.47e-1)" "unprognostic (4.61e-3)" "unprognostic (5.04e-2)" "unprognostic (2.93e-1)" "potential prognostic unfavorable (3.74e-4)" "unprognostic (3.30e-3)" "unprognostic (1.59e-1)" "potential prognostic favorable (8.32e-4)" "unprognostic (1.25e-1)" "unprognostic (3.65e-1)" "potential prognostic favorable (5.18e-5)" "unprognostic (1.01e-2)" "unprognostic (3.92e-2)" "unprognostic (2.50e-1)" "unprognostic (1.79e-1)" "potential prognostic favorable (5.11e-4)" "unprognostic (1.64e-1)" "unprognostic (4.11e-3)" "unprognostic (6.77e-2)" "unprognostic (8.37e-2)" "unprognostic (6.10e-2)" "unprognostic (4.07e-3)" "unprognostic (2.74e-1)" "unprognostic (2.31e-1)" "unprognostic (3.87e-2)" "unprognostic (1.11e-1)" "unprognostic (2.99e-1)" "unprognostic (5.28e-2)" "unprognostic (1.09e-1)" "unprognostic (5.65e-2)" "unprognostic (3.61e-1)" USP21 "USP16, USP23" ENSG00000143258 "Ubiquitin specific peptidase 21" Q9UK80 1 161159450-161165723 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, Chromatin regulator, Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028397 Uncertain Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 49: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 29 Cytosol "Nucleoplasm, Plasma membrane" "HPA028397: " "unprognostic (3.13e-1)" "unprognostic (6.91e-2)" "unprognostic (3.65e-1)" "unprognostic (1.18e-2)" "unprognostic (1.54e-1)" "unprognostic (2.03e-1)" "unprognostic (5.40e-3)" "unprognostic (1.85e-2)" "unprognostic (3.42e-2)" "unprognostic (3.54e-3)" "unprognostic (2.35e-2)" "unprognostic (4.70e-1)" "unprognostic (1.34e-1)" "potential prognostic unfavorable (8.28e-5)" "unprognostic (2.81e-1)" "unprognostic (1.05e-1)" "unprognostic (2.45e-2)" "unprognostic (1.62e-2)" "unprognostic (4.73e-2)" "unprognostic (6.44e-2)" "unprognostic (1.26e-1)" "unprognostic (3.17e-2)" "unprognostic (5.20e-2)" "unprognostic (5.72e-2)" "unprognostic (2.41e-2)" "unprognostic (2.83e-1)" "unprognostic (2.91e-3)" "unprognostic (2.60e-1)" "unprognostic (1.91e-1)" "unprognostic (1.09e-3)" "unprognostic (1.18e-1)" USP22 "KIAA1063, USP3L" ENSG00000124422 "Ubiquitin specific peptidase 22" Q9UPT9 17 20999596-21043760 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, Chromatin regulator, Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044980 Supported Approved "Nuclear speckles" NA NA "Cluster 32: Basophils - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 42: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 84 "Nuclear speckles" "HPA044980: " "unprognostic (4.85e-2)" "unprognostic (4.05e-2)" "unprognostic (1.36e-2)" "unprognostic (1.39e-2)" "unprognostic (4.84e-2)" "unprognostic (2.62e-1)" "unprognostic (1.86e-1)" "potential prognostic favorable (7.36e-4)" "unprognostic (6.83e-2)" "unprognostic (3.46e-3)" "potential prognostic favorable (1.47e-5)" "unprognostic (2.59e-3)" "potential prognostic favorable (2.08e-4)" "unprognostic (1.68e-3)" "unprognostic (1.16e-2)" "unprognostic (3.78e-2)" "unprognostic (9.51e-2)" "unprognostic (6.61e-2)" "unprognostic (2.06e-1)" "unprognostic (3.96e-2)" "unprognostic (6.30e-2)" "unprognostic (4.55e-3)" "unprognostic (2.15e-2)" "unprognostic (8.33e-2)" "unprognostic (1.12e-1)" "unprognostic (3.83e-1)" "unprognostic (7.15e-2)" "unprognostic (5.28e-2)" "unprognostic (1.61e-1)" "unprognostic (7.82e-2)" "unprognostic (8.34e-2)" USP24 KIAA1057 ENSG00000162402 "Ubiquitin specific peptidase 24" Q9UPU5 1 55066359-55215378 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 677.8;Oligodendrocyte progenitor cells: 587.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026723, HPA028428, HPA067124" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 37: Non-specific - mRNA processing" "Cluster 7: Non-specific - Transcription" 10 Nucleoplasm Cytosol "HPA026723: , HPA028428: , HPA067124: " "unprognostic (2.45e-1)" "unprognostic (4.02e-1)" "unprognostic (1.83e-1)" "unprognostic (1.26e-2)" "unprognostic (3.50e-2)" "unprognostic (9.50e-2)" "unprognostic (2.75e-3)" "unprognostic (1.82e-2)" "unprognostic (1.17e-2)" "unprognostic (1.43e-3)" "unprognostic (2.47e-3)" "unprognostic (2.64e-2)" "unprognostic (3.45e-2)" "potential prognostic unfavorable (3.94e-7)" "unprognostic (1.45e-1)" "unprognostic (1.77e-2)" "unprognostic (3.04e-2)" "unprognostic (4.78e-1)" "potential prognostic favorable (2.76e-4)" "unprognostic (2.78e-1)" "unprognostic (1.96e-1)" "unprognostic (1.10e-1)" "unprognostic (9.73e-2)" "unprognostic (1.24e-1)" "unprognostic (2.29e-3)" "unprognostic (2.51e-1)" "unprognostic (5.57e-2)" "unprognostic (5.83e-2)" "unprognostic (1.50e-1)" "unprognostic (5.52e-2)" "unprognostic (1.68e-1)" USP25 USP21 ENSG00000155313 "Ubiquitin specific peptidase 25" Q9UHP3 21 15729982-15880064 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 112.9" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018297, HPA024142" Approved Supported Cytosol NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 7: Non-specific - Transcription" 45 Cytosol "HPA018297: , HPA024142: " "unprognostic (1.94e-1)" "unprognostic (1.17e-1)" "unprognostic (2.68e-1)" "unprognostic (1.41e-2)" "unprognostic (2.07e-1)" "potential prognostic unfavorable (3.45e-4)" "unprognostic (1.05e-1)" "unprognostic (9.62e-2)" "unprognostic (9.99e-3)" "unprognostic (2.41e-2)" "potential prognostic favorable (2.39e-5)" "unprognostic (2.22e-2)" "unprognostic (1.37e-1)" "unprognostic (6.83e-2)" "unprognostic (1.03e-1)" "unprognostic (6.28e-2)" "unprognostic (1.47e-2)" "unprognostic (2.70e-1)" "unprognostic (2.67e-1)" "unprognostic (2.61e-2)" "unprognostic (3.83e-2)" "unprognostic (4.26e-3)" "unprognostic (9.94e-2)" "unprognostic (1.18e-1)" "unprognostic (2.54e-1)" "unprognostic (8.57e-2)" "unprognostic (4.68e-2)" "unprognostic (4.93e-2)" "unprognostic (1.85e-1)" "unprognostic (1.39e-1)" "unprognostic (1.66e-1)" USP26 ENSG00000134588 "Ubiquitin specific peptidase 26" Q9BXU7 X 133023168-133097109 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 1.7;Differentiating spermatogonia: 19.9;Early primary spermatocytes: 4.5;Retinal horizontal cells: 2.0;Undifferentiated spermatogonia: 7.5" "Low cell type specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Sarcoma: 1.0" "Testis - Spermatocytes, Testis - Spermatogonia" "HPA000424, HPA027310, HPA079124" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 65: Non-specific - Unknown function" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 3 Nucleoplasm Cytosol "HPA000424: , HPA027310: , HPA079124: " USP27X USP27 ENSG00000273820 "Ubiquitin specific peptidase 27 X-linked" A6NNY8 X 49879484-49882558 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.5" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 21.3;Alveolar cells type 1: 17.6;Alveolar cells type 2: 18.4;Cytotrophoblasts: 57.8;Migrating cytotrophoblasts: 27.0;Syncytiotrophoblasts: 26.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 11.9" "Adrenal gland - Adrenal cortex cells, Pituitary gland - Corticotropes, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077264 Approved Nucleoplasm,Vesicles NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 36: Non-specific - mRNA processing" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 8 Vesicles Nucleoplasm "HPA077264: " "unprognostic (1.02e-1)" "unprognostic (1.93e-1)" "unprognostic (3.16e-1)" "unprognostic (1.60e-1)" "unprognostic (1.81e-1)" "unprognostic (1.23e-1)" "unprognostic (1.19e-1)" "unprognostic (2.32e-1)" "unprognostic (7.48e-3)" "validated prognostic favorable (4.84e-8)" "validated prognostic favorable (4.03e-4)" "unprognostic (4.99e-2)" "validated prognostic unfavorable (1.89e-4)" "validated prognostic unfavorable (8.11e-4)" "unprognostic (1.02e-2)" "unprognostic (2.22e-1)" "unprognostic (1.38e-1)" "unprognostic (3.72e-3)" "unprognostic (6.00e-2)" "unprognostic (3.63e-3)" "unprognostic (7.49e-2)" "unprognostic (7.15e-2)" "unprognostic (1.31e-1)" "unprognostic (5.30e-2)" "unprognostic (4.01e-2)" "unprognostic (1.22e-1)" "unprognostic (5.97e-2)" "unprognostic (1.02e-1)" USP28 KIAA1515 ENSG00000048028 "Ubiquitin specific peptidase 28" Q96RU2 11 113797874-113875572 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 53.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 185.0;Myonuclei: 170.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006778, HPA006779" Enhanced Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 2: Neurons - Nucleosome" "Cluster 24: Non-specific - Unknown function" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 14 Nucleoplasm "Nuclear bodies" "HPA006778: , HPA006779: " "unprognostic (1.09e-1)" "unprognostic (4.40e-2)" "unprognostic (8.87e-2)" "unprognostic (4.56e-2)" "unprognostic (1.80e-1)" "unprognostic (1.11e-1)" "unprognostic (1.54e-1)" "unprognostic (1.28e-1)" "unprognostic (1.58e-1)" "unprognostic (4.40e-3)" "unprognostic (2.07e-3)" "unprognostic (4.26e-2)" "unprognostic (2.48e-1)" "unprognostic (8.28e-3)" "unprognostic (7.40e-2)" "unprognostic (2.25e-1)" "unprognostic (2.46e-2)" "unprognostic (2.03e-1)" "unprognostic (6.52e-2)" "unprognostic (2.16e-2)" "unprognostic (7.16e-2)" "unprognostic (3.74e-2)" "unprognostic (1.28e-2)" "unprognostic (2.38e-1)" "unprognostic (2.73e-3)" "unprognostic (6.03e-2)" "unprognostic (3.54e-2)" "unprognostic (4.71e-1)" "unprognostic (3.09e-2)" "unprognostic (9.75e-2)" "unprognostic (1.90e-1)" USP29 ENSG00000131864 "Ubiquitin specific peptidase 29" Q9HBJ7 19 57119138-57131926 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "bone marrow: 1.5;testis: 4.6" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 3.1;Early primary spermatocytes: 6.9;Early spermatids: 2.8;Ependymal cells: 1.1;Foveolar cells: 1.2;Gastric chief cells: 1.1;Late primary spermatocytes: 6.2;Undifferentiated spermatogonia: 2.3" "Cell type enriched" "Detected in single" 4 "ependymal cell: 1.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.2" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA076515 Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 39: Testis - Nuclear processes" "Cluster 25: Non-specific - Transcription" "Cluster 56: Non-specific - Sensory perception" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 6 "Plasma membrane" Cytosol "HPA076515: " "unprognostic (6.97e-3)" "unprognostic (1.51e-1)" "unprognostic (1.40e-1)" "unprognostic (1.75e-1)" "unprognostic (2.02e-2)" USP3 ENSG00000140455 "Ubiquitin specific peptidase 3" Q9Y6I4 15 63504511-63594640 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, Ubl conjugation pathway" "Chromatin regulator, Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 628.7;Neutrophils: 1742.1" "Cell type enhanced" "Detected in all" "upper rhombic lip: 395.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053275, HPA060513, HPA077975" Supported "Nucleoplasm,Midbody ring" "Intracellular and membrane" Enzyme Yes No "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 14 Nucleoplasm "Midbody ring" "HPA053275: , HPA060513: , HPA077975: " "unprognostic (1.48e-3)" "unprognostic (5.36e-3)" "unprognostic (3.30e-2)" "unprognostic (9.90e-3)" "unprognostic (2.43e-1)" "unprognostic (1.29e-1)" "unprognostic (2.47e-2)" "potential prognostic favorable (4.76e-4)" "unprognostic (6.13e-2)" "potential prognostic unfavorable (7.70e-4)" "unprognostic (1.09e-1)" "unprognostic (2.39e-3)" "unprognostic (1.01e-1)" "unprognostic (1.04e-1)" "unprognostic (8.08e-2)" "unprognostic (2.74e-2)" "unprognostic (2.69e-1)" "unprognostic (5.36e-2)" "unprognostic (7.15e-2)" "unprognostic (9.17e-2)" "unprognostic (1.06e-1)" "unprognostic (5.36e-2)" "unprognostic (1.64e-2)" "unprognostic (1.23e-1)" "unprognostic (1.26e-2)" "unprognostic (1.38e-1)" "unprognostic (4.73e-2)" "unprognostic (2.85e-2)" "unprognostic (6.90e-2)" "unprognostic (2.79e-3)" "unprognostic (7.77e-2)" USP30 "FLJ40511, MGC10702" ENSG00000135093 "Ubiquitin specific peptidase 30" Q70CQ3 12 109023089-109088023 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 90.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Spleen - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016952 Approved NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 21: Testis - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 9 "HPA016952: " "unprognostic (2.37e-1)" "unprognostic (2.60e-1)" "unprognostic (8.75e-2)" "unprognostic (1.20e-2)" "unprognostic (5.24e-2)" "unprognostic (2.51e-2)" "unprognostic (2.87e-2)" "unprognostic (1.88e-2)" "unprognostic (1.76e-1)" "unprognostic (9.44e-2)" "potential prognostic favorable (1.40e-5)" "unprognostic (1.85e-3)" "unprognostic (1.85e-2)" "unprognostic (1.07e-1)" "unprognostic (1.42e-2)" "unprognostic (2.42e-2)" "unprognostic (2.77e-1)" "unprognostic (1.43e-1)" "unprognostic (8.86e-3)" "unprognostic (1.71e-1)" "unprognostic (8.75e-3)" "unprognostic (1.44e-1)" "unprognostic (7.84e-3)" "unprognostic (1.34e-1)" "unprognostic (1.39e-3)" "unprognostic (4.46e-2)" "unprognostic (3.93e-1)" "unprognostic (5.14e-2)" "unprognostic (1.75e-1)" "unprognostic (6.13e-2)" "unprognostic (6.14e-2)" USP31 KIAA1203 ENSG00000103404 "Ubiquitin specific peptidase 31" Q70CQ4 16 23061406-23149452 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 208.9;Cardiomyocytes: 180.3;Oligodendrocytes: 190.2;Salivary myoepithelial cells: 249.1;Urothelial cells: 179.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006937 Uncertain Approved Cytosol NA NA "Cluster 67: Testis - Mixed function" "Cluster 30: White matter - Myelination" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 69: Urothelial cells - Basic cellular functions" Cytosol "HPA006937: " "unprognostic (4.84e-3)" "unprognostic (5.75e-2)" "unprognostic (1.71e-1)" "unprognostic (2.83e-2)" "unprognostic (3.59e-1)" "unprognostic (3.44e-2)" "unprognostic (1.64e-1)" "unprognostic (2.25e-2)" "unprognostic (2.70e-1)" "unprognostic (8.57e-3)" "unprognostic (5.26e-3)" "unprognostic (1.57e-1)" "unprognostic (1.79e-2)" "unprognostic (5.67e-2)" "unprognostic (5.22e-2)" "unprognostic (1.30e-1)" "unprognostic (2.22e-2)" "unprognostic (1.16e-1)" "unprognostic (2.27e-1)" "unprognostic (1.37e-1)" "unprognostic (2.80e-1)" "unprognostic (7.01e-2)" "unprognostic (1.01e-2)" "unprognostic (4.69e-2)" "unprognostic (5.06e-2)" "unprognostic (6.17e-2)" "unprognostic (2.77e-1)" "unprognostic (2.07e-2)" "unprognostic (1.71e-1)" "unprognostic (3.13e-1)" "unprognostic (1.73e-1)" USP32 "NY-REN-60, USP10" ENSG00000170832 "Ubiquitin specific peptidase 32" Q8NFA0 17 60177327-60422470 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 95.4" "Cell type enriched" "Detected in many" 4 "Neutrophils: 2854.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 59.4" "Group enriched" "Detected in all" 9 "dendritic cells: 59.4;granulocytes: 29.5" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044365 Approved Supported "Golgi apparatus,Cytosol" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 24: Neutrophils - Innate immunity signal integration" 32 "Golgi apparatus" Cytosol "HPA044365: " "unprognostic (4.14e-1)" "unprognostic (2.01e-1)" "unprognostic (1.59e-2)" "unprognostic (7.89e-2)" "unprognostic (9.56e-2)" "unprognostic (7.61e-2)" "unprognostic (9.18e-2)" "unprognostic (1.60e-1)" "unprognostic (4.57e-2)" "potential prognostic unfavorable (1.27e-4)" "potential prognostic favorable (4.64e-4)" "unprognostic (1.35e-1)" "unprognostic (1.05e-3)" "unprognostic (1.57e-3)" "unprognostic (6.93e-3)" "unprognostic (7.21e-2)" "unprognostic (1.45e-1)" "unprognostic (3.21e-2)" "unprognostic (8.02e-2)" "unprognostic (1.63e-1)" "unprognostic (5.99e-3)" "unprognostic (6.12e-2)" "potential prognostic unfavorable (1.01e-4)" "unprognostic (3.48e-1)" "unprognostic (5.35e-1)" "unprognostic (1.79e-2)" "unprognostic (7.21e-2)" "unprognostic (1.90e-2)" "unprognostic (9.20e-2)" "unprognostic (1.45e-2)" "unprognostic (8.49e-3)" USP33 "KIAA1097, VDU1" ENSG00000077254 "Ubiquitin specific peptidase 33" Q8TEY7 1 77695987-77759852 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Endocytosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 469.7;Retinal pigment epithelial cells: 468.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005719 Uncertain Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 27: Cerebellum - Synaptic function" "Cluster 34: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 89: Adipocytes - Lipid metabolism" 19 "Nucleoplasm, Golgi apparatus" "HPA005719: " "unprognostic (1.04e-1)" "unprognostic (1.60e-1)" "unprognostic (1.43e-1)" "unprognostic (3.55e-2)" "unprognostic (1.85e-2)" "unprognostic (4.32e-1)" "unprognostic (1.31e-1)" "unprognostic (2.06e-2)" "unprognostic (1.56e-2)" "potential prognostic unfavorable (1.54e-6)" "unprognostic (1.32e-3)" "potential prognostic favorable (4.68e-4)" "unprognostic (2.54e-2)" "unprognostic (3.05e-3)" "unprognostic (2.00e-1)" "unprognostic (6.44e-2)" "unprognostic (1.42e-1)" "unprognostic (2.65e-1)" "unprognostic (5.35e-2)" "unprognostic (2.12e-1)" "unprognostic (6.92e-3)" "unprognostic (1.49e-1)" "unprognostic (8.03e-2)" "unprognostic (1.61e-1)" "unprognostic (1.69e-2)" "unprognostic (1.89e-2)" "unprognostic (1.63e-1)" "unprognostic (1.90e-1)" "unprognostic (6.51e-2)" "unprognostic (8.60e-2)" "unprognostic (3.68e-2)" USP34 "KIAA0570, KIAA0729" ENSG00000115464 "Ubiquitin specific peptidase 34" Q70CQ2 2 61187463-61471087 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway, Wnt signaling pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025815 Uncertain Approved Vesicles NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 64: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 7: Non-specific - Transcription" 10 Vesicles "HPA025815: " "unprognostic (5.19e-1)" "unprognostic (2.03e-1)" "unprognostic (4.31e-2)" "unprognostic (2.66e-1)" "unprognostic (4.54e-1)" "unprognostic (9.77e-2)" "unprognostic (6.67e-2)" "unprognostic (3.34e-3)" "unprognostic (5.09e-2)" "unprognostic (3.12e-1)" "unprognostic (6.48e-2)" "unprognostic (1.61e-1)" "unprognostic (2.66e-1)" "potential prognostic unfavorable (1.63e-5)" "unprognostic (1.75e-1)" "unprognostic (9.37e-2)" "unprognostic (2.69e-1)" "unprognostic (3.41e-2)" "unprognostic (4.06e-2)" "unprognostic (1.32e-1)" "unprognostic (7.23e-2)" "unprognostic (4.13e-2)" "unprognostic (1.15e-2)" "unprognostic (2.06e-1)" "unprognostic (2.99e-1)" "unprognostic (3.17e-2)" "unprognostic (1.04e-1)" "unprognostic (3.34e-2)" "unprognostic (5.44e-1)" "unprognostic (3.20e-1)" "unprognostic (1.60e-1)" USP35 KIAA1372 ENSG00000118369 "Ubiquitin specific peptidase 35" Q9P2H5 11 78188812-78215232 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 55.2;Late spermatids: 146.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055213, HPA058592" Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 24: Neurons - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 9 "Nucleoli fibrillar center" Nucleoplasm "HPA055213: , HPA058592: " "unprognostic (1.20e-1)" "unprognostic (6.52e-2)" "unprognostic (1.43e-1)" "unprognostic (3.38e-2)" "unprognostic (3.97e-1)" "unprognostic (7.86e-2)" "unprognostic (1.81e-1)" "unprognostic (6.80e-2)" "unprognostic (1.31e-2)" "unprognostic (7.37e-3)" "unprognostic (6.94e-3)" "unprognostic (1.14e-2)" "unprognostic (2.85e-1)" "unprognostic (2.27e-1)" "unprognostic (3.62e-2)" "unprognostic (2.00e-1)" "unprognostic (9.65e-2)" "unprognostic (1.31e-1)" "unprognostic (3.21e-1)" "unprognostic (4.61e-3)" "unprognostic (2.16e-2)" "unprognostic (8.59e-2)" "unprognostic (7.08e-3)" "unprognostic (1.74e-2)" "unprognostic (1.68e-2)" "unprognostic (8.52e-2)" "unprognostic (3.69e-2)" "unprognostic (3.91e-2)" "unprognostic (2.39e-1)" "unprognostic (1.62e-2)" "unprognostic (2.11e-2)" USP36 "FLJ12851, KIAA1453" ENSG00000055483 "Ubiquitin specific peptidase 36" Q9P275 17 78787381-78841441 "Enzymes, Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, RNA-binding, Thiol protease, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 319.9;pDCs: 270.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012082, HPA012395, HPA052860" Uncertain Supported Enhanced "Nucleoli,Nucleoli rim,Nuclear speckles" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 15: Bone marrow - Innate immune response" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 27: Breast cancer - Unknown function" "Cluster 103: Non-specific - Basic cellular processes" 54 "Nucleoli, Nucleoli rim" "Nuclear speckles" "HPA012082: , HPA012395: , HPA052860: " "unprognostic (5.42e-2)" "unprognostic (2.01e-1)" "unprognostic (3.93e-2)" "unprognostic (1.25e-1)" "unprognostic (4.69e-1)" "unprognostic (1.04e-1)" "unprognostic (1.75e-1)" "unprognostic (1.90e-1)" "unprognostic (1.91e-1)" "unprognostic (7.18e-2)" "unprognostic (2.41e-2)" "unprognostic (2.12e-2)" "unprognostic (6.52e-2)" "potential prognostic unfavorable (1.94e-4)" "unprognostic (6.45e-3)" "unprognostic (3.14e-1)" "unprognostic (2.21e-2)" "unprognostic (3.43e-1)" "unprognostic (1.23e-3)" "unprognostic (2.76e-2)" "unprognostic (1.78e-2)" "unprognostic (2.04e-2)" "unprognostic (3.85e-3)" "unprognostic (5.63e-3)" "unprognostic (1.15e-2)" "potential prognostic favorable (7.34e-4)" "unprognostic (1.22e-1)" "unprognostic (2.28e-1)" "unprognostic (1.82e-1)" "unprognostic (1.54e-3)" "unprognostic (5.36e-3)" USP37 KIAA1594 ENSG00000135913 "Ubiquitin specific peptidase 37" Q86T82 2 218450251-218568351 "Enzymes, Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 229.2;Sertoli cells: 277.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045160 Approved Approved Nucleoplasm,Nucleoli NA Yes "Cluster 5: Non-specific - Cell proliferation" "Cluster 40: Non-specific - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 103: Non-specific - Basic cellular processes" 22 "Nucleoplasm, Nucleoli" "HPA045160: " "unprognostic (7.17e-2)" "unprognostic (3.97e-2)" "unprognostic (1.84e-1)" "unprognostic (6.54e-2)" "unprognostic (3.54e-1)" "unprognostic (4.49e-2)" "unprognostic (3.18e-1)" "unprognostic (2.50e-1)" "unprognostic (3.85e-3)" "potential prognostic unfavorable (3.09e-4)" "potential prognostic favorable (7.46e-4)" "unprognostic (1.34e-2)" "unprognostic (4.10e-2)" "potential prognostic unfavorable (4.01e-4)" "unprognostic (1.24e-2)" "unprognostic (9.65e-2)" "unprognostic (3.15e-2)" "unprognostic (5.28e-3)" "unprognostic (1.78e-2)" "unprognostic (2.51e-2)" "unprognostic (1.49e-1)" "unprognostic (2.73e-2)" "potential prognostic unfavorable (7.16e-4)" "unprognostic (1.14e-2)" "unprognostic (8.87e-3)" "unprognostic (2.67e-3)" "unprognostic (5.44e-3)" "unprognostic (4.03e-1)" "unprognostic (2.92e-1)" "unprognostic (6.11e-2)" "unprognostic (2.80e-2)" USP38 "HP43.8KD, KIAA1891" ENSG00000170185 "Ubiquitin specific peptidase 38" Q8NB14 4 143184917-143223874 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 16.1" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 161.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036990, HPA047948" Uncertain Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 7 Nucleoplasm "Centrosome, Cytosol" "HPA036990: , HPA047948: " "unprognostic (6.85e-3)" "unprognostic (1.46e-1)" "unprognostic (6.33e-2)" "unprognostic (2.28e-2)" "unprognostic (1.65e-2)" "unprognostic (3.24e-1)" "unprognostic (2.05e-1)" "unprognostic (1.49e-2)" "unprognostic (1.87e-1)" "unprognostic (1.09e-1)" "validated prognostic favorable (1.62e-8)" "validated prognostic favorable (2.43e-4)" "unprognostic (6.80e-2)" "unprognostic (1.94e-1)" "unprognostic (4.19e-2)" "unprognostic (1.01e-1)" "unprognostic (1.37e-3)" "unprognostic (3.47e-3)" "unprognostic (7.51e-2)" "unprognostic (1.41e-2)" "unprognostic (1.66e-2)" "unprognostic (6.58e-2)" "unprognostic (1.78e-1)" "unprognostic (1.09e-1)" "unprognostic (2.67e-3)" "unprognostic (1.15e-1)" "unprognostic (2.15e-1)" "unprognostic (1.11e-1)" "unprognostic (2.35e-1)" "unprognostic (1.39e-2)" "unprognostic (1.55e-1)" USP39 "CGI-21, SAD1, SNRNP65" ENSG00000168883 "Ubiquitin specific peptidase 39" Q53GS9 2 85602856-85649283 "Enzymes, Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, mRNA processing, mRNA splicing, Ubl conjugation pathway" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cholangiocytes: 346.5;Hepatocytes: 652.9;Kupffer cells: 377.2;Parietal cells: 388.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034823, HPA077350" Supported Supported Supported Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 93: Hepatocytes - Bile production & excretion" 68 Nucleoplasm "HPA034823: , HPA077350: " "unprognostic (5.09e-2)" "unprognostic (4.86e-2)" "unprognostic (3.11e-2)" "unprognostic (6.39e-2)" "unprognostic (1.57e-1)" "unprognostic (8.62e-2)" "unprognostic (8.41e-2)" "unprognostic (1.17e-1)" "unprognostic (3.48e-2)" "unprognostic (3.86e-3)" "unprognostic (5.04e-3)" "unprognostic (2.40e-1)" "unprognostic (1.79e-1)" "potential prognostic unfavorable (4.83e-5)" "unprognostic (2.04e-3)" "unprognostic (9.65e-3)" "unprognostic (1.65e-1)" "unprognostic (9.13e-3)" "unprognostic (3.30e-2)" "unprognostic (8.73e-2)" "unprognostic (1.97e-1)" "unprognostic (3.59e-3)" "unprognostic (1.26e-2)" "unprognostic (2.51e-2)" "unprognostic (2.96e-1)" "unprognostic (7.20e-2)" "unprognostic (1.97e-1)" "unprognostic (1.22e-2)" "unprognostic (9.89e-2)" "unprognostic (1.78e-1)" "unprognostic (3.33e-2)" USP4 "UNP, Unph" ENSG00000114316 "Ubiquitin specific peptidase 4" Q13107 3 49277144-49340712 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 497.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018499, HPA074006" Approved Supported "Nucleoplasm,Vesicles,Basal body,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 38 Nucleoplasm "Vesicles, Basal body, Cytosol" "HPA018499: , HPA074006: " "unprognostic (3.90e-2)" "unprognostic (1.67e-1)" "unprognostic (4.86e-2)" "unprognostic (2.54e-2)" "unprognostic (5.97e-2)" "unprognostic (1.58e-1)" "unprognostic (4.67e-1)" "unprognostic (9.44e-3)" "unprognostic (9.54e-2)" "potential prognostic unfavorable (1.40e-4)" "potential prognostic favorable (6.08e-5)" "unprognostic (6.03e-2)" "potential prognostic favorable (1.54e-4)" "unprognostic (2.52e-2)" "unprognostic (2.46e-3)" "potential prognostic favorable (3.03e-4)" "potential prognostic unfavorable (9.47e-5)" "unprognostic (3.59e-1)" "unprognostic (2.79e-2)" "unprognostic (1.36e-1)" "unprognostic (2.95e-1)" "unprognostic (5.28e-2)" "unprognostic (4.31e-3)" "unprognostic (2.60e-3)" "unprognostic (1.24e-1)" "potential prognostic favorable (7.29e-4)" "unprognostic (4.67e-2)" "unprognostic (1.14e-1)" "unprognostic (1.20e-1)" "unprognostic (1.48e-1)" "unprognostic (2.19e-1)" USP40 FLJ10785 ENSG00000085982 "Ubiquitin specific peptidase 40" Q9NVE5 2 233475526-233566782 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005821 Uncertain Approved "Vesicles,Focal adhesion sites" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 22: Epididymis - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 7: Non-specific - Transcription" 2 Vesicles "Focal adhesion sites" "HPA005821: " "unprognostic (3.78e-1)" "unprognostic (2.33e-2)" "unprognostic (4.39e-2)" "unprognostic (4.85e-3)" "unprognostic (3.78e-1)" "unprognostic (2.94e-2)" "unprognostic (2.26e-1)" "unprognostic (2.20e-2)" "unprognostic (1.94e-2)" "potential prognostic unfavorable (1.67e-4)" "unprognostic (2.93e-3)" "unprognostic (2.01e-3)" "unprognostic (1.24e-2)" "unprognostic (9.80e-2)" "unprognostic (9.48e-2)" "unprognostic (5.37e-2)" "unprognostic (9.81e-2)" "unprognostic (3.29e-1)" "unprognostic (2.90e-1)" "unprognostic (5.68e-2)" "unprognostic (4.82e-2)" "unprognostic (6.03e-2)" "unprognostic (2.94e-2)" "unprognostic (1.33e-1)" "unprognostic (1.26e-2)" "unprognostic (7.78e-3)" "unprognostic (4.65e-2)" "unprognostic (2.22e-1)" "unprognostic (2.75e-2)" "unprognostic (1.05e-1)" "unprognostic (1.83e-2)" USP42 FLJ12697 ENSG00000106346 "Ubiquitin specific peptidase 42" Q9H9J4 7 6104949-6161564 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006939, HPA064800" Approved Nucleoplasm,Nucleoli NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 16: Non-specific - Transcription" "Cluster 67: Non-specific - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 2 Nucleoplasm Nucleoli "HPA006939: , HPA064800: " "unprognostic (3.70e-2)" "unprognostic (6.55e-3)" "unprognostic (9.05e-2)" "unprognostic (1.36e-2)" "unprognostic (2.64e-1)" "unprognostic (6.09e-2)" "unprognostic (4.69e-2)" "unprognostic (1.14e-1)" "unprognostic (3.54e-1)" "unprognostic (1.38e-1)" "potential prognostic favorable (3.51e-4)" "unprognostic (6.72e-3)" "unprognostic (6.78e-2)" "unprognostic (1.10e-2)" "unprognostic (4.12e-1)" "unprognostic (6.26e-2)" "unprognostic (6.92e-2)" "unprognostic (5.65e-2)" "unprognostic (9.63e-3)" "unprognostic (1.68e-1)" "unprognostic (4.24e-2)" "unprognostic (1.03e-2)" "unprognostic (3.40e-3)" "unprognostic (2.27e-2)" "unprognostic (7.71e-3)" "unprognostic (4.04e-1)" "unprognostic (1.83e-1)" "unprognostic (9.11e-3)" "unprognostic (1.96e-1)" "unprognostic (3.08e-2)" "unprognostic (3.49e-2)" USP43 FLJ30626 ENSG00000154914 "Ubiquitin specific peptidase 43" Q70EL4 17 9644698-9729687 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 171.4;Endometrial ciliated cells: 138.1;Endometrial glandular cells: 264.4;Endometrial luminal cells: 163.0;Ependymal cells: 185.2;Extravillous trophoblasts: 257.8;Migrating cytotrophoblasts: 130.1;Prostatic glandular cells: 137.1;Syncytiotrophoblasts: 334.7" "Cell type enhanced" "Detected in many" "ependymal cell: 191.4;oligodendrocyte precursor cell: 111.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Pituitary gland - Corticotropes, Prostate - Prostate glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA023389, HPA027762, HPA027763" Uncertain Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 53: Neurons - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 51: Secretory epithelial cells - Mixed function" 9 "Nucleoplasm, Nuclear speckles" "HPA023389: , HPA027762: , HPA027763: " "unprognostic (3.97e-1)" "unprognostic (7.42e-2)" "unprognostic (6.25e-2)" "unprognostic (4.69e-2)" "unprognostic (4.46e-2)" "unprognostic (9.22e-2)" "unprognostic (9.12e-2)" "potential prognostic favorable (6.06e-4)" "unprognostic (9.73e-3)" "unprognostic (2.22e-1)" "unprognostic (2.33e-3)" "unprognostic (4.58e-2)" "unprognostic (2.41e-2)" "unprognostic (1.58e-1)" "unprognostic (1.71e-3)" "unprognostic (1.96e-1)" "unprognostic (4.86e-2)" "potential prognostic unfavorable (4.99e-4)" "unprognostic (1.01e-3)" "potential prognostic unfavorable (6.97e-4)" "unprognostic (5.63e-2)" "unprognostic (6.69e-3)" "unprognostic (1.58e-2)" "unprognostic (1.89e-1)" "unprognostic (3.67e-2)" "unprognostic (3.51e-2)" "unprognostic (2.94e-3)" "unprognostic (1.43e-1)" "unprognostic (1.55e-1)" "unprognostic (2.75e-1)" USP44 FLJ14528 ENSG00000136014 "Ubiquitin specific peptidase 44" Q9H0E7 12 95516560-95551476 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Immunity, Innate immunity, Mitosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "testis: 22.6" "Group enriched" "Detected in many" 8 "Early spermatids: 480.9;Late primary spermatocytes: 447.8;Late spermatids: 131.3" "Cell type enhanced" "Detected in many" "upper rhombic lip: 31.3" "Group enriched" "Detected in some" 4 "Lung Adenocarcinoma (TCGA): 2.2;Testicular Germ Cell Tumor (TCGA): 6.3" "Region enriched" "Detected in many" 5 "cerebellum: 15.1" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 6.1" "Group enriched" "Detected in many" 41 "B-cells: 4.7;T-cells: 6.1" "Cancer enhanced" "Detected in many" "Leukemia: 11.3;testis cancer: 12.1" "Lung - Alveolar cells type 2, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA026543 Approved "Nucleoli fibrillar center,Microtubules" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 57: Testis - Spermatogenesis" "Cluster 35: Non-specific - DNA binding" "Cluster 59: Leukemia - T-cell receptor" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 16 "Nucleoli fibrillar center, Microtubules" "HPA026543: " "unprognostic (1.12e-1)" "unprognostic (2.84e-3)" "unprognostic (6.30e-3)" "unprognostic (1.69e-1)" "unprognostic (1.67e-1)" "unprognostic (1.26e-1)" "unprognostic (1.42e-2)" USP45 MGC14793 ENSG00000123552 "Ubiquitin specific peptidase 45" Q70EL2 6 99432325-99521728 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Disease variant, Leber congenital amaurosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 213.2;Cardiomyocytes: 366.8;Epicardial cells: 209.2;Oocytes: 234.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029602, HPA029604, HPA075668" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 35: Non-specific - DNA binding" "Cluster 28: Non-specific - Nuclear processes" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 11 "Nucleoplasm, Cytosol" "HPA029602: , HPA029604: , HPA075668: " "unprognostic (6.82e-2)" "unprognostic (1.53e-2)" "unprognostic (1.62e-1)" "unprognostic (1.61e-3)" "unprognostic (5.12e-2)" "unprognostic (8.67e-2)" "unprognostic (9.21e-3)" "unprognostic (1.67e-1)" "unprognostic (1.67e-2)" "unprognostic (1.49e-3)" "unprognostic (2.32e-1)" "unprognostic (5.35e-2)" "unprognostic (3.40e-1)" "unprognostic (1.80e-2)" "unprognostic (5.97e-2)" "unprognostic (1.21e-1)" "unprognostic (1.51e-3)" "unprognostic (1.26e-1)" "unprognostic (2.04e-1)" "unprognostic (1.34e-2)" "unprognostic (3.24e-1)" "unprognostic (1.51e-2)" "unprognostic (1.63e-3)" "unprognostic (2.54e-1)" "unprognostic (1.04e-2)" "unprognostic (1.44e-1)" "unprognostic (6.33e-3)" "unprognostic (2.12e-1)" "unprognostic (2.29e-2)" "unprognostic (6.94e-2)" "unprognostic (3.67e-3)" USP46 FLJ12552 ENSG00000109189 "Ubiquitin specific peptidase 46" P62068 4 52590960-52659301 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Behavior, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 288.1;Esophageal apical cells: 148.6;Podocytes: 305.8;Retinal bipolar cells: 141.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007288, CAB076369, CAB076370" Uncertain Approved "Nucleoli,Nucleoli rim" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 35: Non-specific - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 57: Podocytes - Glomerular filtration" 11 "Nucleoli, Nucleoli rim" "CAB076369: , CAB076370: , HPA007288: " "unprognostic (2.50e-1)" "unprognostic (2.06e-3)" "unprognostic (7.29e-2)" "unprognostic (1.64e-2)" "unprognostic (9.96e-2)" "unprognostic (1.33e-1)" "unprognostic (1.57e-1)" "unprognostic (5.33e-3)" "unprognostic (6.59e-2)" "unprognostic (3.11e-2)" "potential prognostic favorable (1.19e-4)" "unprognostic (1.82e-2)" "unprognostic (1.39e-1)" "potential prognostic unfavorable (4.81e-4)" "unprognostic (1.98e-1)" "unprognostic (9.19e-2)" "unprognostic (2.35e-1)" "unprognostic (1.35e-1)" "unprognostic (8.79e-2)" "unprognostic (6.83e-2)" "unprognostic (7.49e-2)" "unprognostic (1.39e-1)" "unprognostic (3.08e-1)" "unprognostic (1.40e-1)" "unprognostic (7.32e-2)" "unprognostic (6.11e-3)" "unprognostic (1.97e-1)" "unprognostic (1.41e-1)" "unprognostic (4.97e-2)" "unprognostic (2.43e-2)" "unprognostic (1.42e-1)" USP47 ENSG00000170242 "Ubiquitin specific peptidase 47" Q96K76 11 11841423-11961887 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029286, HPA029289" Supported Approved "Vesicles,Intermediate filaments" NA NA 8600 "Cluster 3: Non-specific - Nuclear processes" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 20 "Intermediate filaments" Vesicles "HPA029286: , HPA029289: " "unprognostic (1.02e-1)" "unprognostic (7.61e-2)" "unprognostic (2.96e-1)" "unprognostic (1.27e-1)" "unprognostic (1.67e-1)" "unprognostic (2.45e-2)" "unprognostic (7.08e-2)" "unprognostic (3.38e-2)" "unprognostic (1.67e-1)" "unprognostic (1.96e-1)" "potential prognostic favorable (3.13e-4)" "unprognostic (5.28e-2)" "unprognostic (2.58e-1)" "unprognostic (1.31e-1)" "unprognostic (2.31e-2)" "unprognostic (1.65e-1)" "unprognostic (8.57e-2)" "unprognostic (2.66e-2)" "unprognostic (1.98e-1)" "unprognostic (1.53e-1)" "unprognostic (1.64e-2)" "unprognostic (8.14e-3)" "unprognostic (4.14e-2)" "unprognostic (1.84e-1)" "unprognostic (2.71e-2)" "unprognostic (2.65e-1)" "unprognostic (6.17e-2)" "unprognostic (5.03e-3)" "unprognostic (2.63e-1)" "unprognostic (1.18e-1)" "unprognostic (1.09e-1)" USP48 "FLJ11328, FLJ20103, FLJ23054, FLJ23277, MGC14879, USP31" ENSG00000090686 "Ubiquitin specific peptidase 48" Q86UV5 1 21678298-21783606 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 436.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030045, HPA030046" Approved Supported Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 44: Plasma cells - Antibody production & secretion" 49 Nucleoplasm "Mitochondria, Cytosol" "HPA030045: , HPA030046: " "unprognostic (2.73e-1)" "unprognostic (1.20e-1)" "unprognostic (1.17e-1)" "unprognostic (1.73e-2)" "unprognostic (1.25e-3)" "unprognostic (5.59e-2)" "unprognostic (1.64e-1)" "unprognostic (3.05e-1)" "unprognostic (1.86e-2)" "unprognostic (1.05e-3)" "potential prognostic favorable (2.96e-4)" "unprognostic (1.52e-2)" "unprognostic (1.16e-1)" "potential prognostic unfavorable (1.40e-7)" "unprognostic (1.50e-2)" "unprognostic (1.02e-1)" "unprognostic (9.27e-2)" "unprognostic (3.28e-1)" "unprognostic (5.12e-2)" "unprognostic (7.82e-3)" "unprognostic (2.54e-1)" "unprognostic (6.98e-2)" "unprognostic (1.27e-1)" "unprognostic (9.04e-2)" "unprognostic (8.86e-2)" "unprognostic (8.33e-3)" "unprognostic (2.75e-2)" "unprognostic (1.81e-1)" "unprognostic (3.19e-1)" "unprognostic (2.32e-2)" "unprognostic (2.06e-1)" USP49 MGC20741 ENSG00000164663 "Ubiquitin specific peptidase 49" Q70CQ1 6 41789896-41895375 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, Ubl conjugation pathway" "Chromatin regulator, Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 8.3" "Cell type enhanced" "Detected in many" "Astrocytes: 37.5;Bergmann glia: 31.4;Brain excitatory neurons: 58.4;Brain inhibitory neurons: 60.4;Choroid plexus epithelial cells: 54.7;Distal convoluted tubule cells: 50.7;Ependymal cells: 131.2;Loop of henle epithelial cells: 36.0;Oligodendrocyte progenitor cells: 70.5;Oligodendrocytes: 39.3;Other brain neurons: 51.6;Papillary tip epithelial cells: 30.6;Proximal tubule cells: 29.5;Renal collecting duct intercalated cells: 48.1;Renal connecting tubule cells: 35.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "basophil: 3.6" "Lineage enriched" "Detected in single" 7 "granulocytes: 3.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030254, HPA030255" Uncertain NA NA "Cluster 32: Basophils - Transcription" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 15: Non-specific - Transcription" "Cluster 59: Leukemia - T-cell receptor" "Cluster 102: Non-specific - Mixed function" 17 "HPA030254: , HPA030255: " "unprognostic (1.14e-1)" "unprognostic (9.14e-2)" "unprognostic (1.46e-1)" "unprognostic (1.21e-1)" "unprognostic (2.21e-3)" "unprognostic (2.92e-1)" "unprognostic (2.43e-2)" "potential prognostic favorable (4.09e-4)" "potential prognostic favorable (2.50e-4)" "unprognostic (1.12e-3)" "unprognostic (2.56e-2)" "unprognostic (7.07e-2)" "unprognostic (1.56e-1)" "unprognostic (3.70e-2)" "unprognostic (2.98e-2)" "unprognostic (3.48e-2)" "unprognostic (1.56e-3)" "unprognostic (2.24e-1)" "unprognostic (3.63e-1)" "unprognostic (1.18e-2)" "unprognostic (1.86e-2)" "unprognostic (9.41e-2)" "potential prognostic favorable (4.94e-4)" "unprognostic (5.28e-3)" "unprognostic (1.46e-2)" "unprognostic (3.83e-2)" "unprognostic (8.39e-2)" "unprognostic (5.94e-3)" "unprognostic (6.96e-3)" USP5 IsoT ENSG00000111667 "Ubiquitin specific peptidase 5" P45974 12 6852148-6866632 "Enzymes, Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 100.4;Syncytiotrophoblasts: 69.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006756 Uncertain Approved Nucleoplasm,Cytosol NA NA 1800000 "Cluster 33: Non-specific - ATP binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 1: Neurons - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 38 "Nucleoplasm, Cytosol" "HPA006756: " "unprognostic (2.09e-1)" "unprognostic (1.15e-1)" "unprognostic (3.09e-1)" "unprognostic (7.85e-3)" "unprognostic (3.71e-1)" "unprognostic (3.23e-2)" "unprognostic (4.36e-2)" "unprognostic (1.43e-2)" "unprognostic (2.23e-2)" "unprognostic (4.60e-2)" "potential prognostic favorable (4.65e-4)" "unprognostic (1.17e-2)" "unprognostic (5.34e-1)" "unprognostic (1.95e-2)" "potential prognostic unfavorable (9.27e-4)" "potential prognostic unfavorable (7.27e-4)" "unprognostic (6.92e-2)" "unprognostic (1.19e-1)" "unprognostic (2.39e-1)" "unprognostic (2.99e-2)" "unprognostic (9.78e-2)" "unprognostic (1.70e-1)" "unprognostic (4.17e-2)" "unprognostic (6.45e-2)" "unprognostic (9.35e-2)" "unprognostic (2.29e-2)" "unprognostic (1.10e-1)" "unprognostic (9.58e-2)" "unprognostic (2.94e-1)" "unprognostic (7.00e-2)" "unprognostic (1.70e-1)" USP50 ENSG00000170236 "Ubiquitin specific peptidase 50" Q70EL3 15 50494018-50546708 "Enzymes, Predicted intracellular proteins" "Cell cycle" Hydrolase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 5 "testis: 1.3" "Cell type enhanced" "Detected in many" "Adipocytes: 50.0;Cardiomyocytes: 105.3;Early spermatids: 156.1;Epicardial cells: 195.6;Late primary spermatocytes: 173.4;Late spermatids: 126.2;Oocytes: 156.6;Retinal pigment epithelial cells: 51.2" "Cell type enhanced" "Detected in all" "oligodendrocyte: 24.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA039470 Uncertain NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" 4 "HPA039470: " "unprognostic (6.57e-2)" "unprognostic (2.60e-2)" USP51 ENSG00000247746 "Ubiquitin specific peptidase 51" Q70EK9 X 55484616-55489848 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "epididymis: 46.7" "Cell type enriched" "Detected in many" 6 "Epididymal principal cells: 259.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 6.4" "Skeletal muscle - Fibroblasts, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA001942 Uncertain Approved "Nucleoli fibrillar center,Cytosol" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 36: Non-specific - mRNA processing" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 17 Cytosol "Nucleoli fibrillar center" "HPA001942: " "unprognostic (6.65e-2)" "unprognostic (6.18e-2)" "unprognostic (2.55e-1)" "unprognostic (1.13e-1)" "unprognostic (2.21e-1)" "unprognostic (3.46e-2)" "unprognostic (7.34e-2)" "potential prognostic favorable (1.86e-8)" "unprognostic (4.88e-3)" "unprognostic (4.41e-2)" "unprognostic (2.70e-2)" "unprognostic (2.36e-1)" "unprognostic (1.67e-1)" "unprognostic (2.81e-2)" "unprognostic (1.49e-2)" "unprognostic (4.05e-2)" "unprognostic (1.19e-3)" "unprognostic (2.90e-1)" "unprognostic (1.75e-1)" "unprognostic (6.99e-2)" "unprognostic (1.15e-2)" "unprognostic (4.67e-2)" "unprognostic (1.96e-2)" "unprognostic (1.87e-1)" USP53 KIAA1350 ENSG00000145390 "Ubiquitin specific peptidase 53" Q70EK8 4 119212587-119295518 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Hydrolase "Deafness, Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 2703.1;Endometrial luminal cells: 991.5" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 803.6;fibroblast: 1030.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035844, HPA035845" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 51: Secretory epithelial cells - Mixed function" 9 "Plasma membrane" Cytosol "HPA035844: , HPA035845: " "unprognostic (2.16e-1)" "unprognostic (6.14e-2)" "unprognostic (1.57e-1)" "potential prognostic unfavorable (7.61e-4)" "potential prognostic favorable (5.00e-6)" "unprognostic (6.51e-2)" "unprognostic (7.90e-2)" "unprognostic (2.76e-2)" "unprognostic (1.45e-1)" "unprognostic (3.29e-1)" "validated prognostic favorable (2.70e-6)" "validated prognostic favorable (1.98e-4)" "unprognostic (8.47e-3)" "unprognostic (3.10e-1)" "unprognostic (3.22e-2)" "unprognostic (2.06e-1)" "unprognostic (3.51e-1)" "unprognostic (4.60e-1)" "unprognostic (5.29e-2)" "unprognostic (4.09e-2)" "unprognostic (4.14e-1)" "unprognostic (8.38e-2)" "unprognostic (5.58e-2)" "unprognostic (3.10e-3)" "unprognostic (4.65e-3)" "unprognostic (3.59e-1)" "unprognostic (2.99e-1)" "unprognostic (1.76e-1)" "unprognostic (1.75e-1)" "unprognostic (5.14e-2)" "unprognostic (1.81e-1)" USP54 "bA137L10.3, bA137L10.4, C10orf29, FLJ37318" ENSG00000166348 "Ubiquitin specific peptidase 54" Q70EL1 10 73497538-73626117 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 67.5;skeletal muscle: 122.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 626.0;Myonuclei: 1714.9;Oligodendrocytes: 697.8;Thymic myoid cells: 458.2;Transitional alveolar cells: 538.5" "Cell type enhanced" "Detected in all" "endothelial cell: 823.7;oligodendrocyte: 865.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Breast - Breast glandular cells, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047663, HPA063665" Approved Approved Mitochondria NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 60: Prostate cancer - Unknown function" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 31 Mitochondria "HPA047663: , HPA063665: " "potential prognostic favorable (2.94e-4)" "unprognostic (5.06e-3)" "unprognostic (1.47e-1)" "unprognostic (9.17e-2)" "unprognostic (2.95e-1)" "unprognostic (2.04e-1)" "unprognostic (2.15e-1)" "potential prognostic favorable (7.70e-4)" "unprognostic (5.04e-3)" "unprognostic (8.98e-2)" "unprognostic (4.11e-2)" "unprognostic (6.89e-3)" "unprognostic (1.46e-1)" "unprognostic (2.17e-3)" "unprognostic (1.08e-2)" "potential prognostic favorable (5.58e-5)" "unprognostic (8.20e-2)" "unprognostic (1.56e-1)" "unprognostic (2.64e-1)" "unprognostic (2.25e-2)" "unprognostic (7.74e-2)" "unprognostic (1.86e-3)" "unprognostic (3.35e-1)" "unprognostic (2.35e-1)" "unprognostic (1.48e-2)" "unprognostic (9.63e-2)" "unprognostic (2.72e-2)" "unprognostic (7.90e-2)" "unprognostic (1.96e-1)" "unprognostic (1.76e-2)" "unprognostic (4.97e-2)" USP6 "HRP1, Tre-2, TRE17, Tre2, TRESMCR" ENSG00000129204 "Ubiquitin specific peptidase 6" P35125 17 5116032-5175034 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Calmodulin-binding, Hydrolase, Protease, Thiol protease" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "skeletal muscle: 19.0;testis: 12.4" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 18.8;Early primary spermatocytes: 65.4;Early spermatids: 40.9;Late primary spermatocytes: 18.5;Late spermatids: 28.6;Myonuclei: 90.2;Myosatellite cells: 14.5;Undifferentiated spermatogonia: 22.6" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 14.6;ependymal cell: 8.2" "Cancer enriched" "Detected in single" 8 "Testicular Germ Cell Tumor (TCGA): 3.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Spermatocytes" HPA046969 Supported Vesicles NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 1: Neuronal - Visual perception" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 6 Vesicles "HPA046969: " "unprognostic (3.36e-1)" "unprognostic (7.74e-2)" "unprognostic (2.63e-3)" "unprognostic (1.10e-1)" USP6NL "KIAA0019, RN-tre, RNTRE, TRE2NL, USP6NL-IT1" ENSG00000148429 "USP6 N-terminal like" Q92738 10 11460510-11611666 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 454.8;Esophageal apical cells: 868.9;Microglia: 450.5;Urothelial cells: 366.5" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 540.6;endothelial cell: 593.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory B-cell: 4.8;naive B-cell: 4.0" "Lineage enriched" "Detected in single" 5 "B-cells: 4.8" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Pituitary gland - Corticotropes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039196 Approved NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 51: Secretory epithelial cells - Mixed function" 8 "HPA039196: " "unprognostic (1.85e-2)" "unprognostic (2.86e-2)" "unprognostic (5.58e-2)" "unprognostic (1.17e-3)" "unprognostic (1.65e-1)" "unprognostic (6.23e-3)" "unprognostic (6.69e-3)" "potential prognostic favorable (4.04e-4)" "unprognostic (2.54e-3)" "unprognostic (3.60e-2)" "potential prognostic favorable (1.93e-4)" "unprognostic (1.47e-2)" "unprognostic (1.17e-1)" "unprognostic (1.61e-1)" "unprognostic (9.76e-2)" "unprognostic (7.52e-2)" "unprognostic (8.27e-2)" "unprognostic (1.90e-1)" "unprognostic (9.45e-2)" "unprognostic (2.24e-1)" "unprognostic (4.90e-2)" "unprognostic (4.36e-2)" "unprognostic (3.64e-3)" "unprognostic (1.37e-1)" "unprognostic (3.23e-2)" "unprognostic (1.91e-1)" "unprognostic (1.49e-1)" "unprognostic (3.94e-2)" "unprognostic (2.69e-2)" "unprognostic (8.78e-2)" "unprognostic (2.03e-2)" USP7 HAUSP ENSG00000187555 "Ubiquitin specific peptidase 7" Q93009 16 8892097-8975328 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, DNA damage, DNA repair, Host-virus interaction, Ubl conjugation pathway" "Developmental protein, Hydrolase, Protease, Thiol protease" "Autism spectrum disorder, Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 332.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008108, HPA015641, CAB079904" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 15000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 39: Testis - Nuclear processes" "Cluster 14: Neurons - Synaptic function" "Cluster 54: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 286 Nucleoplasm "Nuclear bodies, Cytosol" "CAB008108: , CAB079904: , HPA015641: " "unprognostic (3.99e-2)" "unprognostic (3.68e-2)" "unprognostic (2.75e-3)" "unprognostic (1.21e-1)" "unprognostic (8.42e-2)" "unprognostic (1.61e-1)" "unprognostic (2.79e-1)" "unprognostic (2.82e-1)" "unprognostic (5.51e-2)" "unprognostic (6.98e-2)" "potential prognostic favorable (8.25e-5)" "unprognostic (6.65e-3)" "unprognostic (1.71e-2)" "unprognostic (9.99e-2)" "unprognostic (1.11e-1)" "unprognostic (1.01e-1)" "unprognostic (2.71e-3)" "unprognostic (1.09e-1)" "unprognostic (5.27e-2)" "unprognostic (1.18e-2)" "unprognostic (1.06e-2)" "unprognostic (6.31e-3)" "unprognostic (7.03e-2)" "unprognostic (1.21e-1)" "unprognostic (8.57e-3)" "unprognostic (3.73e-1)" "unprognostic (2.48e-1)" "unprognostic (2.43e-1)" "unprognostic (2.25e-2)" "unprognostic (6.61e-3)" "unprognostic (5.47e-2)" USP8 "HumORF8, KIAA0055, SPG59, UBPY" ENSG00000138592 "Ubiquitin specific peptidase 8" P40818 15 50424380-50514421 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Cancer-related genes, Cushing syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 455.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Endothelial cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050215 Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 32: Basophils - Transcription" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 44: Non-specific - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 69 Vesicles "Nucleoplasm, Golgi apparatus, Cytosol" "HPA050215: " "unprognostic (1.03e-1)" "unprognostic (1.02e-2)" "unprognostic (2.66e-2)" "unprognostic (9.56e-2)" "unprognostic (7.02e-2)" "unprognostic (1.48e-1)" "unprognostic (6.12e-2)" "unprognostic (4.37e-1)" "unprognostic (3.03e-1)" "potential prognostic unfavorable (2.25e-5)" "potential prognostic favorable (6.74e-7)" "unprognostic (1.62e-3)" "unprognostic (7.77e-2)" "unprognostic (2.60e-1)" "unprognostic (2.46e-1)" "unprognostic (3.04e-1)" "unprognostic (3.55e-1)" "unprognostic (3.32e-2)" "unprognostic (2.89e-1)" "unprognostic (2.35e-2)" "unprognostic (1.71e-1)" "unprognostic (9.12e-3)" "unprognostic (1.48e-2)" "unprognostic (1.33e-1)" "unprognostic (1.57e-2)" "unprognostic (1.29e-1)" "unprognostic (1.05e-1)" "unprognostic (9.54e-2)" "unprognostic (3.12e-1)" "unprognostic (8.82e-2)" "unprognostic (1.22e-1)" USP9X "DFFRX, FAF, MRX99" ENSG00000124486 "Ubiquitin specific peptidase 9 X-linked" Q93008 X 41085445-41236579 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Cell division, Chromosome partition, Mitosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 982.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011618, CAB070164" Approved Supported Cytosol NA NA 16000 "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 5: Rhabdoid - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 99 Cytosol "CAB011618: , CAB070164: " "unprognostic (3.20e-1)" "unprognostic (1.05e-2)" "unprognostic (1.46e-1)" "unprognostic (1.27e-1)" "potential prognostic favorable (8.89e-4)" "unprognostic (1.15e-1)" "unprognostic (7.85e-2)" "unprognostic (2.43e-1)" "unprognostic (3.29e-1)" "potential prognostic unfavorable (5.35e-4)" "potential prognostic favorable (5.46e-5)" "unprognostic (7.77e-2)" "unprognostic (7.53e-2)" "unprognostic (1.35e-2)" "unprognostic (4.34e-2)" "unprognostic (1.76e-2)" "unprognostic (9.28e-3)" "unprognostic (1.38e-1)" "unprognostic (2.41e-2)" "unprognostic (3.18e-1)" "unprognostic (4.63e-2)" "unprognostic (6.17e-2)" "unprognostic (1.31e-1)" "unprognostic (8.93e-2)" "unprognostic (4.63e-3)" "unprognostic (8.01e-2)" "unprognostic (1.15e-1)" "unprognostic (1.57e-1)" "unprognostic (6.56e-2)" "unprognostic (1.38e-1)" "unprognostic (2.30e-1)" USP9Y "AZFA, DFFRY" ENSG00000114374 "Ubiquitin specific peptidase 9 Y-linked" O00507 Y 12537650-12860839 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 1208.7;Cone photoreceptor cells: 474.1;Sertoli cells: 603.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 12.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 30.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA057687 Uncertain Vesicles NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 64: Non-specific - Transcription" "Cluster 5: Non-specific - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 2 Vesicles "HPA057687: " "unprognostic (6.40e-2)" "unprognostic (1.48e-2)" "unprognostic (7.82e-2)" "unprognostic (1.26e-1)" "unprognostic (4.95e-2)" "potential prognostic favorable (1.33e-5)" "unprognostic (3.74e-1)" "unprognostic (5.42e-3)" "unprognostic (3.90e-2)" "unprognostic (9.01e-2)" "unprognostic (5.07e-3)" "unprognostic (3.15e-1)" "unprognostic (2.07e-1)" "unprognostic (3.72e-2)" "unprognostic (1.21e-1)" "unprognostic (8.27e-2)" "unprognostic (9.30e-2)" "unprognostic (2.39e-1)" "unprognostic (4.45e-2)" "unprognostic (4.32e-3)" "unprognostic (2.54e-3)" "unprognostic (2.50e-1)" "unprognostic (5.39e-2)" USPL1 "bA121O19.1, C13orf22, D13S106E" ENSG00000132952 "Ubiquitin specific peptidase like 1" Q5W0Q7 13 30617693-30660770 "Enzymes, Essential proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 200.8;Early spermatids: 205.0;Late spermatids: 577.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039342, HPA040172" Uncertain NA NA "Cluster 24: Non-specific - Transcription" "Cluster 47: Testis - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 19: Non-specific - Unknown function" "Cluster 75: Non-specific - Chaperones and protein folding" 13 "HPA039342: , HPA040172: " "unprognostic (2.37e-1)" "unprognostic (3.23e-2)" "unprognostic (1.99e-1)" "unprognostic (1.49e-2)" "unprognostic (1.96e-1)" "unprognostic (1.07e-1)" "unprognostic (1.18e-1)" "unprognostic (2.06e-1)" "unprognostic (2.28e-1)" "unprognostic (2.36e-1)" "unprognostic (4.04e-3)" "unprognostic (6.97e-3)" "unprognostic (4.94e-2)" "unprognostic (9.71e-3)" "unprognostic (1.53e-1)" "unprognostic (2.28e-1)" "unprognostic (8.76e-3)" "unprognostic (4.47e-2)" "unprognostic (7.43e-2)" "unprognostic (8.50e-3)" "unprognostic (1.44e-1)" "unprognostic (1.54e-2)" "potential prognostic unfavorable (1.77e-4)" "unprognostic (1.09e-1)" "unprognostic (1.01e-1)" "unprognostic (1.71e-2)" "unprognostic (1.30e-1)" "unprognostic (2.06e-1)" "unprognostic (2.09e-1)" "unprognostic (2.29e-1)" "unprognostic (1.21e-1)" UST 2OST ENSG00000111962 "Uronyl 2-sulfotransferase" Q9Y2C2 6 148747030-149076990 "Metabolic proteins, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bergmann glia: 526.4;Fibro-adipogenic progenitors: 622.8;Oligodendrocyte progenitor cells: 589.8;Renal collecting duct intercalated cells: 462.3" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 1018.7;oligodendrocyte precursor cell: 785.5" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 22.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 2.5" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Breast - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032022 Approved NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 65: Brain - Transcription" "Cluster 44: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 11 "HPA032022: " "unprognostic (3.79e-2)" "unprognostic (2.83e-1)" "unprognostic (1.01e-1)" "unprognostic (1.16e-1)" "unprognostic (8.96e-2)" "unprognostic (3.11e-1)" "unprognostic (3.66e-2)" "unprognostic (1.28e-2)" "unprognostic (2.01e-1)" "unprognostic (7.01e-2)" "unprognostic (1.09e-1)" "unprognostic (5.70e-3)" "potential prognostic unfavorable (9.77e-4)" "potential prognostic favorable (4.96e-4)" "unprognostic (1.25e-1)" "potential prognostic favorable (3.42e-4)" "unprognostic (6.39e-2)" "unprognostic (1.09e-2)" "unprognostic (4.46e-3)" "unprognostic (1.93e-1)" "unprognostic (3.41e-1)" "unprognostic (1.09e-1)" "unprognostic (1.94e-1)" "unprognostic (1.06e-1)" "unprognostic (1.01e-2)" "unprognostic (1.42e-1)" "unprognostic (2.58e-1)" "unprognostic (5.39e-2)" "unprognostic (1.65e-1)" UTF1 ENSG00000171794 "Undifferentiated embryonic cell transcription factor 1" Q5T230 10 133230217-133231558 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 10 "testis: 5.4" "Cell type enhanced" "Detected in some" "cDC: 19.2;Differentiating spermatogonia: 8.4;Fallopian tube ciliated cells: 16.2;Granulosa cells: 8.1;monocytes: 4.7;Oocytes: 4.6;Respiratory ciliated cells: 7.3;Undifferentiated spermatogonia: 76.6" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 366 "Testicular Germ Cell Tumor (TCGA): 91.9" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Spermatogonia" CAB022384 Enhanced NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 15: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 82: Dendritic cells - Antigen presentation" 1 "CAB022384: " "unprognostic (3.11e-1)" UTP11 "CGI-94, UTP11L" ENSG00000183520 "UTP11 small subunit processome component" Q9Y3A2 1 38009258-38024820 "Essential proteins, Predicted intracellular proteins" "rRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "skeletal muscle: 111.8;tongue: 79.8" "Cell type enhanced" "Detected in many" "Oocytes: 156.6;Thymic myoid cells: 235.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027650, HPA045830" Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 3 Nucleoli "Nucleoplasm, Cytosol" "HPA027650: , HPA045830: " "unprognostic (6.40e-2)" "unprognostic (3.95e-2)" "unprognostic (2.52e-2)" "unprognostic (2.69e-1)" "unprognostic (3.13e-1)" "unprognostic (4.10e-2)" "unprognostic (1.17e-2)" "unprognostic (2.95e-2)" "unprognostic (9.62e-3)" "unprognostic (2.78e-2)" "unprognostic (4.59e-1)" "unprognostic (1.10e-3)" "potential prognostic unfavorable (5.27e-11)" "unprognostic (4.19e-1)" "unprognostic (8.06e-2)" "unprognostic (2.38e-1)" "unprognostic (8.38e-2)" "unprognostic (2.78e-3)" "unprognostic (9.78e-2)" "unprognostic (9.31e-2)" "unprognostic (1.84e-1)" "unprognostic (1.28e-1)" "unprognostic (1.95e-1)" "unprognostic (3.67e-1)" "unprognostic (3.95e-2)" "unprognostic (1.73e-2)" "unprognostic (7.04e-2)" "unprognostic (2.38e-1)" "unprognostic (7.33e-2)" UTP14A "NY-CO-16, SDCCAG16, Utp14" ENSG00000156697 "UTP14A small subunit processome component" Q9BVJ6 X 129906121-129929761 "Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 82.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA047217, HPA054023, CAB079950" Uncertain Supported Nucleoli,Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 54: Non-specific - Ribosome" "Cluster 11: White matter - Signal transduction" "Cluster 36: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 68 Nucleoli Cytosol "CAB079950: , HPA047217: , HPA054023: " "unprognostic (7.78e-2)" "unprognostic (9.57e-3)" "unprognostic (2.32e-1)" "unprognostic (1.30e-1)" "unprognostic (1.11e-2)" "unprognostic (1.44e-2)" "unprognostic (1.10e-1)" "unprognostic (1.19e-1)" "unprognostic (1.29e-3)" "unprognostic (1.07e-3)" "unprognostic (2.98e-3)" "unprognostic (1.08e-1)" "unprognostic (3.26e-3)" "unprognostic (2.00e-3)" "unprognostic (1.34e-3)" "unprognostic (6.55e-2)" "potential prognostic unfavorable (6.64e-5)" "unprognostic (5.77e-2)" "unprognostic (4.33e-1)" "unprognostic (7.10e-2)" "unprognostic (2.56e-1)" "potential prognostic unfavorable (6.78e-4)" "unprognostic (1.48e-1)" "unprognostic (1.73e-2)" "unprognostic (1.26e-2)" "unprognostic (2.32e-1)" "unprognostic (3.78e-3)" "unprognostic (1.16e-1)" "unprognostic (5.34e-2)" "unprognostic (1.16e-1)" "unprognostic (1.87e-1)" UTP14C "2700066J21Rik, KIAA0266" ENSG00000253797 "UTP14C small subunit processome component" Q5TAP6 13 52024691-52033600 "Predicted intracellular proteins" "Differentiation, Meiosis, Ribosome biogenesis, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 12 "Distal convoluted tubule cells: 10.4;Loop of henle epithelial cells: 12.0;Papillary tip epithelial cells: 6.9;Podocytes: 13.9;Proximal tubule cells: 11.3;Renal collecting duct intercalated cells: 10.4;Renal collecting duct principal cells: 8.1;Renal connecting tubule cells: 8.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047217, HPA054023" Uncertain Approved Nucleoli,Cytosol NA NA "Cluster 68: Non-specific - Basic cellular processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 27: Breast cancer - Unknown function" "Cluster 105: Non-specific - Mixed function" 17 Nucleoli Cytosol "HPA047217: , HPA054023: " "unprognostic (4.90e-2)" "unprognostic (9.70e-3)" "unprognostic (1.36e-3)" "unprognostic (2.93e-1)" "unprognostic (5.39e-2)" "unprognostic (1.22e-1)" "unprognostic (1.31e-2)" "unprognostic (1.45e-2)" "unprognostic (1.12e-1)" "unprognostic (2.07e-2)" "unprognostic (5.75e-3)" "unprognostic (1.20e-1)" "unprognostic (2.96e-1)" "unprognostic (2.09e-3)" "unprognostic (2.31e-3)" "unprognostic (1.36e-3)" "unprognostic (2.58e-1)" "unprognostic (2.11e-1)" "unprognostic (3.12e-2)" "unprognostic (2.31e-2)" "unprognostic (4.19e-1)" "unprognostic (2.98e-1)" "unprognostic (4.20e-1)" UTP15 "FLJ12787, FLJ23637, NET21" ENSG00000164338 "UTP15 small subunit processome component" Q8TED0 5 73565443-73583380 "Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 34.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 54.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044697 Approved "Nucleoli,Endoplasmic reticulum" No No "Cluster 3: Non-specific - Nuclear processes" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 34: Non-specific - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 17: Non-specific - RNA processing" 26 "Nucleoli, Endoplasmic reticulum" "HPA044697: " "unprognostic (2.02e-1)" "unprognostic (1.01e-1)" "unprognostic (4.50e-1)" "unprognostic (1.66e-2)" "unprognostic (3.10e-2)" "unprognostic (3.22e-2)" "unprognostic (9.12e-2)" "unprognostic (2.95e-1)" "unprognostic (1.81e-1)" "potential prognostic unfavorable (5.58e-5)" "unprognostic (1.65e-2)" "unprognostic (1.59e-1)" "unprognostic (4.18e-2)" "unprognostic (7.43e-2)" "unprognostic (6.20e-2)" "unprognostic (3.94e-3)" "unprognostic (2.43e-3)" "unprognostic (8.71e-2)" "unprognostic (6.12e-2)" "unprognostic (1.19e-2)" "unprognostic (4.24e-3)" "unprognostic (8.16e-3)" "unprognostic (1.56e-2)" "unprognostic (4.12e-2)" "unprognostic (3.86e-2)" "unprognostic (3.68e-1)" "unprognostic (2.37e-1)" "unprognostic (2.87e-1)" "unprognostic (1.76e-1)" "unprognostic (1.35e-2)" "unprognostic (3.89e-2)" UTP18 "CGI-48, WDR50" ENSG00000011260 "UTP18 small subunit processome component" Q9Y5J1 17 51260546-51297936 "Essential proteins, Predicted intracellular proteins" "rRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 207.5;Late primary spermatocytes: 201.7;Late spermatids: 268.5;Oocytes: 184.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052378 Approved Supported "Nucleoplasm,Nuclear membrane,Nucleoli,Nucleoli rim" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 39: Testis - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 17: Non-specific - RNA processing" 33 "Nucleoli, Nucleoli rim" "Nucleoplasm, Nuclear membrane" "HPA052378: " "unprognostic (6.18e-3)" "unprognostic (9.73e-3)" "unprognostic (1.39e-1)" "unprognostic (1.53e-1)" "potential prognostic favorable (4.83e-4)" "unprognostic (2.70e-2)" "unprognostic (5.60e-3)" "unprognostic (9.25e-2)" "unprognostic (1.73e-3)" "potential prognostic unfavorable (2.37e-4)" "potential prognostic favorable (6.56e-6)" "unprognostic (9.57e-2)" "unprognostic (1.70e-3)" "validated prognostic unfavorable (2.62e-4)" "validated prognostic unfavorable (2.15e-7)" "unprognostic (3.17e-2)" "unprognostic (1.74e-3)" "unprognostic (1.02e-1)" "unprognostic (2.38e-2)" "unprognostic (2.07e-1)" "unprognostic (1.94e-2)" "unprognostic (2.78e-1)" "unprognostic (5.39e-3)" "unprognostic (5.67e-3)" "unprognostic (5.12e-3)" "unprognostic (1.00e-2)" "unprognostic (4.30e-2)" "unprognostic (2.06e-1)" "unprognostic (1.94e-1)" "unprognostic (7.70e-2)" "unprognostic (6.16e-2)" UTP20 "1A6/DRIM, DRIM" ENSG00000120800 "UTP20 small subunit processome component" O75691 12 101280105-101386618 "Essential proteins, Predicted intracellular proteins" "rRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Lacrimal acinar cells: 211.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049341 Supported "Nucleoli,Plasma membrane" No No "Cluster 30: Non-specific - DNA binding" "Cluster 39: Testis - Nuclear processes" "Cluster 11: White matter - Signal transduction" "Cluster 38: Non-specific - Transcription" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 12 Nucleoli "Plasma membrane" "HPA049341: " "unprognostic (7.55e-2)" "unprognostic (1.16e-2)" "unprognostic (6.62e-2)" "unprognostic (1.23e-2)" "unprognostic (2.69e-2)" "unprognostic (1.09e-1)" "unprognostic (2.68e-1)" "unprognostic (3.37e-1)" "unprognostic (8.81e-2)" "unprognostic (1.41e-1)" "potential prognostic favorable (1.28e-4)" "unprognostic (3.10e-2)" "unprognostic (1.50e-1)" "validated prognostic unfavorable (6.57e-6)" "validated prognostic unfavorable (3.84e-4)" "unprognostic (1.78e-1)" "unprognostic (3.60e-2)" "unprognostic (1.60e-1)" "unprognostic (4.02e-2)" "unprognostic (2.20e-2)" "unprognostic (5.91e-3)" "unprognostic (1.92e-2)" "unprognostic (8.86e-3)" "unprognostic (7.04e-2)" "unprognostic (6.27e-2)" "unprognostic (3.25e-3)" "unprognostic (4.54e-2)" "unprognostic (1.49e-1)" "unprognostic (3.86e-1)" "unprognostic (6.51e-2)" "unprognostic (1.84e-1)" UTP23 "C8orf53, MGC14595" ENSG00000147679 "UTP23 small subunit processome component" Q9BRU9 8 116766505-116849463 "Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044418 Uncertain Approved Nucleoli NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" 38 Nucleoli "HPA044418: " "unprognostic (1.45e-1)" "potential prognostic unfavorable (9.06e-5)" "unprognostic (3.00e-2)" "unprognostic (2.77e-3)" "unprognostic (6.45e-2)" "unprognostic (2.07e-2)" "unprognostic (1.71e-1)" "unprognostic (1.42e-2)" "unprognostic (1.78e-2)" "potential prognostic unfavorable (1.97e-5)" "unprognostic (6.66e-3)" "unprognostic (3.93e-3)" "unprognostic (1.25e-2)" "unprognostic (5.93e-2)" "unprognostic (1.01e-2)" "unprognostic (4.70e-2)" "unprognostic (9.19e-3)" "unprognostic (2.16e-1)" "unprognostic (1.79e-2)" "unprognostic (1.28e-1)" "unprognostic (1.19e-1)" "unprognostic (9.00e-3)" "unprognostic (6.07e-3)" "unprognostic (2.46e-3)" "unprognostic (5.69e-2)" "unprognostic (1.39e-1)" "unprognostic (5.93e-2)" "unprognostic (3.48e-1)" "unprognostic (2.60e-1)" "unprognostic (2.13e-2)" "unprognostic (2.04e-1)" UTP25 "C1orf107, DEF, DIEXF, MGC29875" ENSG00000117597 "UTP25 small subunit processome component" Q68CQ4 1 209827972-209857565 "Essential proteins, Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026640 Approved NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 55: Breast - Lactation" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 45: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 36 "HPA026640: " "unprognostic (8.12e-2)" "unprognostic (2.38e-3)" "unprognostic (1.48e-3)" "unprognostic (1.93e-1)" "unprognostic (2.07e-2)" "unprognostic (2.06e-1)" "unprognostic (9.51e-2)" "unprognostic (1.09e-1)" "unprognostic (1.28e-2)" "potential prognostic favorable (4.69e-4)" "unprognostic (2.73e-2)" "potential prognostic unfavorable (5.17e-4)" "unprognostic (7.80e-3)" "unprognostic (2.04e-1)" "potential prognostic unfavorable (3.39e-4)" "unprognostic (1.52e-1)" "unprognostic (2.71e-1)" "unprognostic (5.92e-2)" "potential prognostic unfavorable (2.60e-4)" "potential prognostic unfavorable (8.64e-5)" "unprognostic (1.00e-1)" "unprognostic (1.78e-1)" "unprognostic (2.10e-3)" "unprognostic (5.25e-2)" "unprognostic (7.40e-2)" "unprognostic (9.90e-2)" "unprognostic (1.44e-1)" "unprognostic (2.49e-2)" "unprognostic (3.26e-1)" UTP3 "CRLZ1, DKFZp761F222, FLJ23256, SAS10" ENSG00000132467 "UTP3 small subunit processome component" Q9NQZ2 4 70688532-70690551 "Essential proteins, Predicted intracellular proteins" "Chromatin regulator, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035655, HPA041453" Approved Supported Nucleoli,Vesicles NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 17: Non-specific - RNA processing" 67 Nucleoli Vesicles "HPA035655: , HPA041453: " "unprognostic (1.37e-1)" "unprognostic (2.34e-2)" "unprognostic (3.18e-2)" "unprognostic (7.90e-3)" "unprognostic (2.62e-2)" "unprognostic (8.08e-2)" "unprognostic (1.36e-1)" "unprognostic (7.20e-2)" "unprognostic (5.79e-3)" "unprognostic (1.67e-1)" "validated prognostic favorable (4.09e-6)" "validated prognostic favorable (2.93e-4)" "unprognostic (1.09e-1)" "potential prognostic unfavorable (1.93e-5)" "unprognostic (1.01e-1)" "unprognostic (4.82e-2)" "unprognostic (2.02e-2)" "unprognostic (5.57e-2)" "unprognostic (5.40e-3)" "unprognostic (1.27e-1)" "unprognostic (1.55e-2)" "unprognostic (9.98e-2)" "unprognostic (3.29e-3)" "unprognostic (6.85e-3)" "unprognostic (3.95e-3)" "unprognostic (2.49e-1)" "unprognostic (2.59e-2)" "unprognostic (6.49e-2)" "unprognostic (6.21e-2)" "unprognostic (7.47e-2)" "unprognostic (5.18e-2)" UTP4 "CIRH1A, CIRHIN, FLJ14728, KIAA1988, NAIC, TEX292" ENSG00000141076 "UTP4 small subunit processome component" Q969X6 16 69131291-69231130 "Essential proteins, Human disease related genes, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 133.5;Proximal tubule cells: 76.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041139, HPA043542" Approved Supported "Nucleoli fibrillar center" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 17: Non-specific - RNA processing" 39 "Nucleoli fibrillar center" "HPA041139: , HPA043542: " "unprognostic (1.91e-2)" "unprognostic (6.45e-2)" "unprognostic (4.46e-2)" "unprognostic (3.37e-1)" "unprognostic (1.06e-1)" "unprognostic (2.01e-3)" "unprognostic (5.93e-2)" "unprognostic (2.03e-2)" "unprognostic (1.70e-2)" "potential prognostic favorable (9.98e-8)" "unprognostic (4.55e-3)" "unprognostic (6.62e-2)" "potential prognostic unfavorable (3.26e-6)" "unprognostic (1.10e-1)" "unprognostic (1.02e-3)" "unprognostic (9.26e-2)" "unprognostic (6.77e-3)" "unprognostic (2.57e-1)" "unprognostic (6.67e-2)" "unprognostic (1.62e-2)" "potential prognostic unfavorable (2.52e-4)" "unprognostic (3.05e-2)" "unprognostic (7.15e-3)" "unprognostic (2.28e-1)" "unprognostic (2.34e-1)" "unprognostic (1.29e-1)" "unprognostic (1.92e-1)" "unprognostic (7.84e-2)" "unprognostic (6.01e-2)" UTP6 "C17orf40, HCA66" ENSG00000108651 "UTP6 small subunit processome component" Q9NYH9 17 31860904-31901708 "Essential proteins, Predicted intracellular proteins" "rRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Bile duct cancer: 59.2" "Spleen - B-cells (Spleen), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025936, HPA055806" Supported Enhanced "Nucleoli,Mitotic chromosome" Yes No "Cluster 13: Non-specific - Mitochondria" "Cluster 64: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 17: Non-specific - RNA processing" 8 Nucleoli "Mitotic chromosome" "HPA025936: , HPA055806: " "unprognostic (3.93e-1)" "unprognostic (5.04e-2)" "unprognostic (9.90e-2)" "unprognostic (1.69e-2)" "unprognostic (4.34e-1)" "unprognostic (3.59e-1)" "unprognostic (3.33e-2)" "unprognostic (7.42e-3)" "unprognostic (4.50e-2)" "unprognostic (2.71e-1)" "potential prognostic unfavorable (5.56e-8)" "unprognostic (1.07e-3)" "unprognostic (4.58e-1)" "validated prognostic unfavorable (3.80e-5)" "validated prognostic unfavorable (4.05e-5)" "unprognostic (1.13e-2)" "potential prognostic unfavorable (1.85e-4)" "unprognostic (5.07e-2)" "unprognostic (1.41e-2)" "unprognostic (1.13e-1)" "unprognostic (2.02e-2)" "unprognostic (1.88e-2)" "unprognostic (1.91e-3)" "unprognostic (1.65e-1)" "unprognostic (1.14e-1)" "potential prognostic favorable (7.66e-4)" "unprognostic (5.22e-2)" "unprognostic (1.79e-1)" "unprognostic (3.38e-1)" "unprognostic (6.44e-2)" "unprognostic (1.31e-1)" UTRN "DMDL, DRP, DRP1" ENSG00000152818 Utrophin P46939 6 144285335-144853034 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 1287.3" "Cell type enhanced" "Detected in all" "endothelial cell: 1762.0;pericyte: 1749.0;vascular associated smooth muscle cell: 2274.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 157.0" "Lineage enriched" "Detected in all" 4 "monocytes: 157.0" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Lung - Alveolar cells type 1, Skeletal muscle - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016348, HPA018894" Enhanced Supported "Nucleoplasm,Plasma membrane,Primary cilium,Basal body" NA NA 16000 "Cluster 40: Monocytes - Innate immune response" "Cluster 61: Non-specific - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 57 "Plasma membrane" "Nucleoplasm, Primary cilium, Basal body" "CAB016348: , HPA018894: " "unprognostic (3.61e-2)" "unprognostic (1.22e-1)" "unprognostic (6.66e-2)" "unprognostic (6.57e-2)" "unprognostic (1.19e-1)" "unprognostic (7.02e-2)" "unprognostic (5.53e-2)" "unprognostic (1.54e-1)" "unprognostic (7.61e-2)" "unprognostic (4.24e-3)" "validated prognostic favorable (4.36e-7)" "validated prognostic favorable (5.33e-5)" "unprognostic (2.12e-1)" "unprognostic (1.57e-3)" "unprognostic (3.77e-1)" "unprognostic (7.65e-2)" "unprognostic (2.82e-1)" "unprognostic (2.57e-2)" "unprognostic (1.36e-1)" "unprognostic (7.01e-2)" "unprognostic (2.11e-1)" "unprognostic (1.28e-1)" "unprognostic (1.33e-1)" "unprognostic (2.99e-1)" "unprognostic (1.32e-2)" "unprognostic (2.63e-2)" "unprognostic (2.79e-1)" "unprognostic (4.08e-2)" "unprognostic (3.38e-1)" "unprognostic (2.90e-1)" "unprognostic (2.40e-1)" UTS2 "PRO1068, U-II, UCN2, UII" ENSG00000049247 "Urotensin 2" O95399 1 7843083-7853512 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 3.7;bone marrow: 2.7;brain: 6.4" "Cell type enhanced" "Detected in some" "Adipocytes: 11.0;Cardiomyocytes: 29.5;Cone photoreceptor cells: 8.3;Enteric stem cells: 8.4;Enteric transient amplifying cells: 10.0;Epicardial cells: 20.5;Mast cells: 38.9;Megakaryocyte progenitors: 8.1;Megakaryocytes: 12.4;NK-cells: 17.7;Paneth cells: 15.5;Retinal bipolar cells: 9.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 6 "medulla oblongata: 99.2;pons: 59.5;white matter: 50.5" "Immune cell enriched" "Detected in many" 5 "T-reg: 45.4" "Lineage enriched" "Detected in many" 5 "T-cells: 45.4" "Cancer enriched" "Detected in many" 9 "Bone cancer: 52.5" "Region enriched" "Detected in single" 19 "pons and medulla: 6.1" "Region enriched" "Detected in some" 12 "spinal cord: 99.2" HPA017000 Uncertain "Secreted to blood" Hormone NA NA 2590000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 43: Hindbrain - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 58: Mast cells - Allergic inflammatory responses" "HPA017000: " "unprognostic (4.25e-2)" "unprognostic (2.15e-1)" "unprognostic (4.44e-2)" "potential prognostic unfavorable (5.96e-4)" "unprognostic (1.37e-1)" "unprognostic (1.32e-1)" "unprognostic (7.66e-2)" "unprognostic (1.10e-1)" "unprognostic (2.33e-1)" "unprognostic (1.83e-1)" "unprognostic (1.24e-1)" "unprognostic (2.30e-1)" "unprognostic (7.48e-2)" "unprognostic (9.06e-2)" "unprognostic (5.36e-2)" "unprognostic (4.60e-2)" "unprognostic (9.02e-2)" "unprognostic (7.80e-2)" "unprognostic (2.55e-1)" "unprognostic (4.85e-3)" UTS2B "U2B, URP, UTS2D" ENSG00000188958 "Urotensin 2B" Q765I0 3 191267168-191330526 "Predicted secreted proteins" Hormone "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "intestine: 3.2;retina: 5.9" "Cell type enhanced" "Detected in some" "Adipocytes: 25.7;Cardiomyocytes: 89.7;Epicardial cells: 50.0;Late primary spermatocytes: 23.6;Late spermatids: 15.0;Undifferentiated spermatogonia: 22.8;Vascular endothelial cells: 11.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory B-cell: 2.9;naive B-cell: 1.8" "Lineage enriched" "Detected in single" 5 "B-cells: 2.9" "Group enriched" "Detected in some" 4 "lymphoma: 9.8;Rhabdoid: 2.9" "Testis - Early spermatids" "Region enriched" "Detected in some" 9 "pons and medulla: 11.3" "Region enriched" "Detected in single" 46 "spinal cord: 13.6" HPA026992 Uncertain "Secreted - unknown location" Hormone NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 42: Retina - Visual perception" "Cluster 9: Non-specific - Receptor signaling" "Cluster 59: Leukemia - T-cell receptor" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "HPA026992: " "unprognostic (5.56e-2)" "unprognostic (4.06e-1)" "unprognostic (1.00e-1)" "unprognostic (2.25e-2)" "unprognostic (2.23e-1)" "potential prognostic favorable (9.86e-5)" "unprognostic (1.70e-2)" "unprognostic (5.33e-2)" "unprognostic (2.58e-1)" "unprognostic (6.10e-2)" "unprognostic (2.40e-2)" "unprognostic (1.30e-2)" "unprognostic (2.27e-1)" "unprognostic (1.64e-1)" UTS2R GPR14 ENSG00000181408 "Urotensin 2 receptor" Q9UKP6 17 82371765-82377458 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Early primary spermatocytes: 33.4;Early spermatids: 8.0;Epididymal efferent duct ciliated cells: 2.9;Late spermatids: 8.4;Myosatellite cells: 5.1;Plasma cells: 1.9;Thymic myoid cells: 2.7" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 2.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 2.0" "Lineage enriched" "Detected in single" 10 "granulocytes: 2.0" "Cancer enhanced" "Detected in many" "Myeloma: 22.0" "Heart muscle - Cardiomyocytes, Skeletal muscle - Fibroblasts" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 48: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 3: Early primary spermatocytes - Early meiosis" "unprognostic (1.73e-1)" "unprognostic (3.24e-1)" "unprognostic (2.69e-2)" UTY "KDM6AL, KDM6C" ENSG00000183878 "Ubiquitously transcribed tetratricopeptide repeat containing, Y-linked" O14607 Y 13234577-13480673 "Enzymes, Predicted intracellular proteins" "Chromatin regulator, Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Neutrophils: 480.0;Sertoli cells: 663.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA000568, HPA001165" Supported Approved "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 47: Leukemia - Hemostasis" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 2 Nucleoplasm "Nucleoli, Nucleoli rim" "HPA000568: , HPA001165: " "unprognostic (1.92e-1)" "unprognostic (2.89e-2)" "unprognostic (6.24e-2)" "unprognostic (1.14e-1)" "unprognostic (1.27e-2)" "potential prognostic favorable (8.45e-6)" "unprognostic (1.89e-1)" "unprognostic (2.97e-2)" "unprognostic (1.54e-1)" "unprognostic (3.61e-2)" "unprognostic (8.97e-3)" "unprognostic (3.28e-1)" "unprognostic (1.27e-1)" "unprognostic (6.69e-2)" "unprognostic (3.82e-1)" "unprognostic (1.17e-1)" "unprognostic (5.69e-2)" "unprognostic (2.21e-1)" "unprognostic (1.94e-2)" "unprognostic (5.24e-2)" "unprognostic (1.02e-2)" "unprognostic (3.15e-2)" "unprognostic (1.57e-1)" "unprognostic (1.55e-1)" UVRAG VPS38 ENSG00000198382 "UV radiation resistance associated" Q9P2Y5 11 75815210-76144232 "Disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "B-cells: 672.8;cDC: 823.2;Choroid plexus epithelial cells: 870.8;Microglia: 612.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016932 Uncertain NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 55: Lymphoma - Immune response" "Cluster 82: Dendritic cells - Antigen presentation" 65 "HPA016932: " "unprognostic (1.65e-1)" "unprognostic (2.30e-1)" "unprognostic (5.55e-3)" "unprognostic (1.54e-1)" "unprognostic (1.32e-1)" "unprognostic (3.55e-2)" "unprognostic (3.05e-1)" "unprognostic (1.21e-1)" "unprognostic (8.22e-3)" "potential prognostic unfavorable (3.55e-5)" "potential prognostic favorable (7.49e-6)" "unprognostic (3.55e-3)" "unprognostic (1.44e-1)" "unprognostic (1.50e-2)" "unprognostic (1.17e-1)" "unprognostic (1.70e-1)" "unprognostic (9.79e-3)" "unprognostic (2.51e-1)" "unprognostic (4.54e-2)" "unprognostic (1.12e-1)" "unprognostic (1.45e-1)" "unprognostic (1.67e-2)" "unprognostic (4.35e-3)" "unprognostic (1.52e-1)" "unprognostic (1.65e-1)" "unprognostic (4.49e-3)" "unprognostic (2.56e-1)" "unprognostic (1.53e-1)" "unprognostic (1.59e-1)" "unprognostic (1.51e-2)" "unprognostic (4.94e-2)" UVSSA KIAA1530 ENSG00000163945 "UV stimulated scaffold protein A" Q2YD98 4 1345691-1395989 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Lactotrophs: 140.0;Somatotrophs: 194.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 3.3" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA050824, HPA053496" Approved Supported Nucleoplasm NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 10 Nucleoplasm "HPA050824: , HPA053496: " "unprognostic (4.02e-2)" "unprognostic (6.56e-3)" "unprognostic (8.29e-3)" "unprognostic (7.13e-2)" "unprognostic (1.62e-1)" "unprognostic (2.27e-1)" "unprognostic (2.35e-1)" "potential prognostic favorable (1.12e-4)" "unprognostic (1.21e-2)" "unprognostic (5.20e-2)" "unprognostic (5.91e-2)" "unprognostic (1.89e-3)" "unprognostic (7.86e-3)" "unprognostic (1.37e-2)" "unprognostic (2.86e-1)" "unprognostic (3.65e-1)" "unprognostic (2.65e-2)" "unprognostic (6.26e-2)" "unprognostic (8.89e-3)" "potential prognostic favorable (4.81e-4)" "potential prognostic unfavorable (1.42e-4)" "unprognostic (2.47e-2)" "unprognostic (1.35e-3)" "unprognostic (3.23e-2)" "unprognostic (3.93e-1)" "unprognostic (1.54e-2)" "unprognostic (4.11e-1)" "unprognostic (2.49e-3)" "unprognostic (1.19e-2)" UXS1 "FLJ23591, SDR6E1, UGD" ENSG00000115652 "UDP-glucuronate decarboxylase 1" Q8NBZ7 2 106093308-106194301 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Platelets: 330.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Lung - Alveolar cells type 1, Spleen - Fibroblasts_1, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008825 Uncertain "Intracellular and membrane" Enzyme NA NA 16000 "Cluster 6: T-cells - T-cell receptor" "Cluster 72: Kidney - Transmembrane transport" "Cluster 38: Sub-cortical - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 51: Secretory epithelial cells - Mixed function" 2 "HPA008825: " "unprognostic (2.37e-1)" "unprognostic (1.69e-1)" "unprognostic (4.71e-2)" "unprognostic (3.80e-2)" "unprognostic (1.10e-1)" "unprognostic (6.63e-2)" "unprognostic (3.32e-1)" "unprognostic (5.29e-2)" "unprognostic (4.84e-3)" "unprognostic (8.54e-2)" "potential prognostic favorable (4.95e-4)" "unprognostic (7.02e-3)" "unprognostic (6.02e-3)" "validated prognostic unfavorable (4.27e-4)" "validated prognostic unfavorable (5.50e-4)" "unprognostic (1.72e-1)" "unprognostic (5.75e-3)" "unprognostic (1.34e-1)" "unprognostic (1.37e-2)" "unprognostic (6.22e-2)" "unprognostic (4.27e-2)" "unprognostic (7.30e-2)" "unprognostic (1.00e-1)" "unprognostic (1.95e-1)" "unprognostic (2.58e-1)" "unprognostic (3.24e-2)" "unprognostic (3.30e-1)" "unprognostic (1.73e-2)" "unprognostic (1.80e-1)" "unprognostic (2.78e-1)" "unprognostic (2.50e-2)" UXT "ART-27, STAP1" ENSG00000126756 "Ubiquitously expressed prefoldin like chaperone" Q9UBK9 X 47651796-47659180 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" "Activator, Chaperone, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050499, HPA058400" Approved Approved "Centriolar satellite,Basal body" NA No "Cluster 18: Non-specific - Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 15: Non-specific - Protein processing" 110 "Centriolar satellite, Basal body" "HPA050499: , HPA058400: " "unprognostic (8.26e-2)" "unprognostic (9.17e-2)" "unprognostic (2.32e-1)" "unprognostic (1.71e-3)" "unprognostic (5.55e-2)" "unprognostic (4.61e-2)" "unprognostic (3.99e-1)" "unprognostic (1.41e-1)" "unprognostic (2.50e-1)" "unprognostic (9.24e-3)" "unprognostic (5.99e-3)" "unprognostic (1.40e-1)" "potential prognostic unfavorable (4.28e-4)" "validated prognostic unfavorable (1.93e-4)" "validated prognostic unfavorable (5.84e-5)" "unprognostic (2.27e-1)" "unprognostic (5.92e-3)" "unprognostic (7.19e-2)" "unprognostic (3.14e-1)" "unprognostic (2.28e-2)" "unprognostic (1.85e-1)" "unprognostic (6.72e-2)" "unprognostic (3.33e-1)" "unprognostic (1.61e-1)" "unprognostic (9.21e-2)" "unprognostic (3.62e-1)" "unprognostic (1.93e-1)" "unprognostic (1.28e-1)" "unprognostic (3.93e-1)" "unprognostic (3.10e-1)" "unprognostic (3.49e-2)" VAC14 "ArPIKfyve, FLJ10305, TAX1BP2" ENSG00000103043 "VAC14 component of PIKFYVE complex" Q08AM6 16 70687439-70801160 "Disease related genes, Predicted intracellular proteins" "Host-virus interaction" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Late spermatids: 607.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027766, HPA075382" Approved Supported Vesicles,Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 140 Vesicles Cytosol "HPA027766: , HPA075382: " "unprognostic (1.33e-2)" "unprognostic (6.97e-2)" "unprognostic (3.13e-2)" "potential prognostic favorable (9.39e-4)" "unprognostic (9.24e-3)" "unprognostic (1.61e-1)" "unprognostic (1.22e-1)" "potential prognostic favorable (1.99e-4)" "unprognostic (3.13e-1)" "unprognostic (7.38e-2)" "unprognostic (1.13e-1)" "unprognostic (6.11e-3)" "potential prognostic favorable (1.76e-4)" "potential prognostic unfavorable (7.37e-4)" "unprognostic (3.49e-2)" "unprognostic (2.54e-2)" "unprognostic (1.20e-1)" "unprognostic (2.79e-2)" "unprognostic (1.05e-1)" "unprognostic (1.00e-2)" "unprognostic (2.21e-1)" "unprognostic (1.82e-1)" "potential prognostic unfavorable (3.35e-4)" "unprognostic (1.62e-1)" "unprognostic (2.06e-2)" "unprognostic (3.24e-3)" "unprognostic (1.83e-1)" "unprognostic (1.76e-1)" "unprognostic (1.40e-1)" "unprognostic (3.53e-2)" "unprognostic (4.16e-2)" VAMP1 "SYB1, VAMP-1" ENSG00000139190 "Vesicle associated membrane protein 1" P23763 12 6462237-6470677 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Congenital myasthenic syndrome, Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 108.8" "Cell type enhanced" "Detected in many" "Neutrophils: 24.8;Tuft cells: 34.6" "Cell type enhanced" "Detected in all" "lower rhombic lip: 72.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002779, CAB016119, CAB079000" Approved Supported NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 45: Non-specific - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 109: Neurons - Neuronal signaling" 9 "CAB002779: , CAB016119: , CAB079000: " "unprognostic (4.22e-2)" "unprognostic (2.19e-1)" "unprognostic (1.45e-1)" "unprognostic (1.67e-2)" "unprognostic (1.97e-2)" "unprognostic (1.01e-1)" "unprognostic (2.10e-1)" "unprognostic (9.17e-2)" "unprognostic (2.24e-2)" "unprognostic (6.15e-2)" "potential prognostic unfavorable (3.93e-8)" "unprognostic (3.03e-2)" "unprognostic (6.70e-2)" "unprognostic (3.15e-2)" "unprognostic (2.54e-1)" "unprognostic (5.06e-3)" "unprognostic (1.24e-1)" "unprognostic (2.23e-2)" "unprognostic (2.67e-2)" "unprognostic (2.65e-1)" "unprognostic (2.30e-2)" "unprognostic (3.98e-2)" "unprognostic (6.75e-2)" "unprognostic (5.87e-2)" "unprognostic (3.36e-1)" "unprognostic (5.19e-2)" "unprognostic (1.12e-1)" "unprognostic (1.37e-1)" "unprognostic (1.67e-1)" "unprognostic (2.14e-1)" "unprognostic (1.32e-2)" VAMP2 "SYB2, VAMP-2" ENSG00000220205 "Vesicle associated membrane protein 2" P63027 17 8159149-8163546 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Disease variant, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 463.9" "Cell type enhanced" "Detected in many" "Bergmann glia: 90.3;Brain excitatory neurons: 239.0;Brain inhibitory neurons: 253.3;Oligodendrocyte progenitor cells: 96.4;Oligodendrocytes: 150.0;Other brain neurons: 333.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pituitary gland - Lactotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB078785 Supported NA NA 5200000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 42: Non-specific - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" 82 "CAB078785: " "potential prognostic favorable (4.21e-4)" "unprognostic (7.77e-2)" "unprognostic (2.21e-1)" "unprognostic (3.75e-2)" "unprognostic (5.81e-2)" "unprognostic (6.25e-2)" "unprognostic (4.41e-2)" "unprognostic (1.30e-1)" "unprognostic (8.18e-2)" "unprognostic (6.82e-2)" "validated prognostic favorable (1.13e-5)" "validated prognostic favorable (2.06e-4)" "potential prognostic favorable (6.92e-5)" "unprognostic (6.73e-2)" "potential prognostic favorable (4.83e-4)" "unprognostic (5.39e-3)" "unprognostic (2.94e-2)" "unprognostic (7.98e-2)" "unprognostic (2.02e-1)" "unprognostic (3.73e-1)" "unprognostic (4.49e-2)" "potential prognostic favorable (1.84e-5)" "unprognostic (1.12e-2)" "unprognostic (8.93e-2)" "unprognostic (3.39e-1)" "unprognostic (1.78e-1)" "unprognostic (1.82e-1)" "unprognostic (3.93e-2)" "unprognostic (1.26e-1)" "unprognostic (8.32e-2)" "potential prognostic favorable (7.84e-5)" VAMP3 CEB ENSG00000049245 "Vesicle associated membrane protein 3" Q15836 1 7771296-7781432 "Cancer-related genes, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 297.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 37: Non-specific - mRNA processing" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 194 "unprognostic (1.10e-1)" "unprognostic (2.99e-2)" "unprognostic (1.23e-1)" "unprognostic (5.00e-2)" "unprognostic (3.37e-3)" "unprognostic (2.26e-1)" "unprognostic (5.80e-2)" "unprognostic (2.28e-3)" "unprognostic (1.73e-2)" "potential prognostic unfavorable (2.46e-5)" "potential prognostic favorable (1.02e-8)" "unprognostic (6.39e-3)" "unprognostic (5.21e-3)" "unprognostic (5.04e-3)" "unprognostic (1.58e-2)" "unprognostic (1.07e-1)" "unprognostic (1.87e-2)" "unprognostic (5.05e-2)" "unprognostic (2.21e-2)" "unprognostic (1.85e-1)" "unprognostic (7.08e-2)" "unprognostic (8.14e-3)" "unprognostic (2.78e-1)" "unprognostic (3.64e-1)" "unprognostic (4.82e-2)" "unprognostic (2.16e-2)" "unprognostic (1.53e-1)" "unprognostic (4.55e-2)" "unprognostic (9.76e-2)" "unprognostic (1.24e-1)" "unprognostic (1.12e-1)" VAMP4 ENSG00000117533 "Vesicle associated membrane protein 4" O75379 1 171700160-171742074 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 91.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050418 Enhanced Approved "Golgi apparatus" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 27: Cerebellum - Synaptic function" "Cluster 19: Astrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 75 "Golgi apparatus" "HPA050418: " "unprognostic (7.78e-2)" "unprognostic (5.27e-2)" "unprognostic (1.78e-1)" "unprognostic (8.02e-2)" "unprognostic (1.50e-1)" "unprognostic (1.86e-1)" "unprognostic (5.98e-2)" "unprognostic (2.11e-1)" "unprognostic (1.44e-1)" "potential prognostic unfavorable (2.69e-4)" "unprognostic (1.00e-2)" "unprognostic (3.07e-1)" "unprognostic (4.31e-2)" "unprognostic (1.36e-1)" "unprognostic (1.95e-1)" "unprognostic (7.01e-2)" "unprognostic (1.86e-2)" "unprognostic (6.98e-2)" "unprognostic (2.61e-1)" "unprognostic (1.85e-1)" "potential prognostic unfavorable (4.35e-4)" "unprognostic (3.77e-3)" "unprognostic (1.05e-2)" "unprognostic (8.81e-2)" "unprognostic (1.28e-1)" "unprognostic (9.54e-2)" "unprognostic (6.29e-2)" "unprognostic (2.43e-1)" "unprognostic (4.95e-2)" "unprognostic (9.86e-2)" "unprognostic (2.13e-1)" VAMP5 ENSG00000168899 "Vesicle associated membrane protein 5" O95183 2 85584431-85593406 "Predicted membrane proteins" "Differentiation, Myogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 246.2;Hepatocytes: 231.7;Kupffer cells: 465.3;Lymphatic endothelial cells: 182.9;Melanocytes: 303.8;Vascular endothelial cells: 291.4" "Cell type enhanced" "Detected in many" "endothelial cell: 69.1;fibroblast: 61.3;pericyte: 92.1;vascular associated smooth muscle cell: 44.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose visceral - Endothelial cells, Kidney - Endothelial cells, Minor Salivary Gland - Endothelial cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035082 Supported Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 24: Non-specific - Transcription" "Cluster 44: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 153 "Nucleoplasm, Plasma membrane" "HPA035082: " "unprognostic (2.22e-1)" "unprognostic (2.13e-1)" "unprognostic (4.40e-3)" "unprognostic (7.02e-3)" "unprognostic (1.92e-1)" "unprognostic (2.45e-2)" "unprognostic (2.81e-2)" "unprognostic (1.80e-3)" "unprognostic (8.71e-3)" "unprognostic (3.74e-2)" "unprognostic (5.95e-2)" "unprognostic (1.71e-1)" "unprognostic (4.53e-3)" "unprognostic (4.71e-3)" "unprognostic (6.55e-3)" "unprognostic (2.63e-3)" "unprognostic (1.29e-2)" "unprognostic (2.29e-1)" "unprognostic (1.30e-1)" "unprognostic (1.15e-1)" "unprognostic (4.53e-1)" "unprognostic (6.71e-2)" "unprognostic (2.92e-2)" "unprognostic (1.42e-1)" "unprognostic (4.30e-2)" "unprognostic (2.00e-1)" "unprognostic (2.14e-1)" "unprognostic (4.27e-2)" "unprognostic (7.37e-2)" "unprognostic (9.04e-3)" "unprognostic (7.70e-2)" VAMP7 "SYBL1, TI-VAMP, VAMP-7" ENSG00000124333 "Vesicle associated membrane protein 7" P51809 X 155881345-155943769 "Predicted intracellular proteins, Predicted membrane proteins" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Platelets: 114.2;Syncytiotrophoblasts: 95.4" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" HPA036733 Approved Supported Vesicles NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 76: Non-specific - Metabolism" "Cluster 27: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 7: Non-specific - Transcription" 40 Vesicles "HPA036733: " "unprognostic (1.46e-2)" "unprognostic (5.73e-2)" "unprognostic (3.27e-1)" "unprognostic (5.00e-2)" "unprognostic (3.10e-1)" "unprognostic (1.57e-2)" "unprognostic (6.68e-2)" "unprognostic (4.59e-2)" "potential prognostic unfavorable (4.58e-4)" "potential prognostic favorable (1.98e-7)" "unprognostic (1.35e-1)" "unprognostic (2.62e-1)" "unprognostic (3.51e-2)" "unprognostic (3.87e-2)" "unprognostic (4.02e-2)" "unprognostic (1.21e-1)" "unprognostic (3.28e-1)" "unprognostic (7.54e-2)" "unprognostic (5.83e-3)" "unprognostic (4.56e-2)" "unprognostic (1.52e-1)" "unprognostic (9.15e-2)" "unprognostic (1.33e-1)" "unprognostic (9.38e-2)" "unprognostic (6.45e-2)" "unprognostic (6.66e-2)" "unprognostic (4.13e-1)" "unprognostic (1.10e-1)" "unprognostic (1.84e-1)" VAMP8 "EDB, VAMP-8" ENSG00000118640 "Vesicle associated membrane protein 8" Q9BV40 2 85561562-85582031 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiviral defense, Autophagy, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1144.3;Enterocytes: 1101.4;Esophageal apical cells: 2859.8;Esophageal suprabasal cells: 1459.7;Hofbauer cells: 1456.6;Kupffer cells: 1309.8;Syncytiotrophoblasts: 1028.0" "Cell type enhanced" "Detected in all" "leukocyte: 37.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adrenal gland - Macrophages, Breast - Breast glandular cells, Heart muscle - Macrophages, Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Macrophages, Skin - Keratinocyte (other), Spleen - Macrophages, Stomach - Gastric mucous cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006882, HPA007215, CAB037132, CAB037147" Enhanced Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA 79000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 60 "Golgi apparatus, Plasma membrane" Nucleoplasm "CAB037132: , CAB037147: , HPA006882: , HPA007215: " "unprognostic (1.38e-1)" "unprognostic (1.61e-1)" "unprognostic (4.29e-2)" "unprognostic (1.16e-1)" "unprognostic (3.37e-2)" "unprognostic (3.84e-1)" "unprognostic (4.33e-2)" "unprognostic (1.59e-1)" "unprognostic (6.74e-2)" "unprognostic (1.05e-1)" "potential prognostic favorable (2.92e-4)" "unprognostic (2.54e-1)" "unprognostic (1.17e-2)" "unprognostic (5.78e-3)" "unprognostic (1.06e-2)" "unprognostic (2.71e-3)" "unprognostic (2.46e-1)" "unprognostic (1.28e-1)" "unprognostic (6.20e-3)" "unprognostic (9.88e-2)" "unprognostic (8.35e-2)" "unprognostic (2.98e-3)" "unprognostic (9.58e-2)" "unprognostic (1.48e-1)" "unprognostic (1.28e-1)" "unprognostic (6.00e-3)" "unprognostic (2.25e-2)" "unprognostic (1.33e-1)" "unprognostic (4.35e-2)" "potential prognostic favorable (1.76e-4)" "unprognostic (8.73e-2)" VANGL1 STB2 ENSG00000173218 "VANGL planar cell polarity protein 1" Q8TAA9 1 115641970-115698224 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 54.6;Late spermatids: 83.5;Megakaryocyte progenitors: 60.1" "Cell type enhanced" "Detected in many" "endothelial cell: 29.9;ependymal cell: 28.1;thalamic excitatory: 32.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 6.2" "Group enriched" "Detected in many" 7 "dendritic cells: 2.3;NK-cells: 6.2;T-cells: 3.0" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Fibroblasts_1, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025235, CAB076375" Approved Approved "Plasma membrane" NA Yes "Cluster 33: Non-specific - ATP binding" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 17 "Plasma membrane" "CAB076375: , HPA025235: " "unprognostic (3.27e-1)" "unprognostic (6.69e-3)" "unprognostic (1.09e-1)" "unprognostic (2.60e-3)" "unprognostic (3.03e-3)" "unprognostic (1.91e-2)" "unprognostic (4.35e-2)" "unprognostic (3.99e-2)" "unprognostic (8.00e-2)" "unprognostic (3.69e-2)" "potential prognostic favorable (4.47e-7)" "unprognostic (1.01e-3)" "unprognostic (8.79e-2)" "unprognostic (2.85e-3)" "potential prognostic unfavorable (2.17e-4)" "validated prognostic unfavorable (4.66e-4)" "validated prognostic unfavorable (2.33e-4)" "unprognostic (1.69e-1)" "unprognostic (3.96e-1)" "unprognostic (3.08e-2)" "unprognostic (5.94e-2)" "unprognostic (1.09e-3)" "unprognostic (1.42e-1)" "unprognostic (4.98e-2)" "unprognostic (4.08e-3)" "unprognostic (1.42e-1)" "unprognostic (2.14e-1)" "unprognostic (1.34e-1)" "unprognostic (1.81e-1)" "unprognostic (4.52e-2)" "unprognostic (2.64e-1)" VANGL2 "KIAA1215, LPP1, LTAP, MGC119403, MGC119404, STB1, STBM, STBM1" ENSG00000162738 "VANGL planar cell polarity protein 2" Q9ULK5 1 160400564-160428670 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 35.5" "Cell type enhanced" "Detected in many" "Astrocytes: 23.7;Cone photoreceptor cells: 24.8;Pituitary stem cells: 33.9;Prostatic hillock cells: 25.7;Tuft cells: 34.6" "Cell type enhanced" "Detected in many" "astrocyte: 38.8;ependymal cell: 31.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 36.1;testis cancer: 33.8" "Pituitary gland - Undifferentiated cells (Pituitary gland)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027043 Uncertain NA NA "Cluster 2: Non-specific - Mixed function" "Cluster 46: Brainstem - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 70: Intestinal goblet cells - Mucin production" 21 "HPA027043: " "unprognostic (3.07e-2)" "unprognostic (2.78e-3)" "unprognostic (3.55e-2)" "unprognostic (4.66e-2)" "unprognostic (8.74e-2)" "unprognostic (4.17e-2)" "unprognostic (8.22e-2)" "unprognostic (7.35e-3)" "unprognostic (2.17e-1)" "unprognostic (9.40e-2)" "unprognostic (3.39e-2)" "unprognostic (8.91e-2)" "unprognostic (6.98e-2)" "unprognostic (1.52e-1)" "unprognostic (1.85e-1)" "unprognostic (1.04e-1)" "unprognostic (7.19e-3)" "unprognostic (2.09e-1)" "unprognostic (3.29e-1)" "unprognostic (9.11e-2)" "unprognostic (5.13e-2)" "unprognostic (1.01e-1)" "unprognostic (6.63e-2)" "unprognostic (4.14e-1)" "potential prognostic unfavorable (5.56e-5)" "unprognostic (5.99e-2)" "unprognostic (1.50e-1)" "unprognostic (5.16e-2)" "unprognostic (1.23e-1)" VAPA "hVAP-33, VAP-A" ENSG00000101558 "VAMP associated protein A" Q9P0L0 18 9914016-9960021 "Plasma proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1109.7;Neutrophils: 981.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009174 Approved Enhanced "Endoplasmic reticulum" NA NA 520000 "Cluster 29: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 24: Neutrophils - Innate immunity signal integration" 368 "Endoplasmic reticulum" "HPA009174: " "unprognostic (5.55e-2)" "unprognostic (4.22e-1)" "unprognostic (2.39e-1)" "unprognostic (5.90e-2)" "unprognostic (3.11e-2)" "unprognostic (1.58e-1)" "unprognostic (2.28e-1)" "unprognostic (7.79e-2)" "unprognostic (4.59e-2)" "unprognostic (1.04e-1)" "validated prognostic favorable (1.39e-9)" "validated prognostic favorable (8.47e-4)" "unprognostic (3.46e-1)" "unprognostic (6.40e-2)" "unprognostic (2.27e-3)" "unprognostic (7.25e-2)" "unprognostic (7.69e-2)" "unprognostic (1.64e-1)" "unprognostic (2.81e-1)" "unprognostic (2.28e-1)" "unprognostic (6.95e-2)" "unprognostic (2.98e-2)" "unprognostic (1.76e-2)" "unprognostic (1.47e-1)" "unprognostic (1.44e-1)" "unprognostic (6.53e-2)" "unprognostic (5.38e-1)" "unprognostic (1.49e-1)" "unprognostic (2.36e-1)" "unprognostic (3.49e-1)" "unprognostic (1.11e-1)" VAPB "ALS8, VAP-B, VAP-C" ENSG00000124164 "VAMP associated protein B and C" O95292 20 58389229-58451101 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction, Unfolded protein response" "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Platelets: 209.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013144, CAB013722" Supported Enhanced "Endoplasmic reticulum" NA NA 110000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 47: Platelets - Hemostasis" 237 "Endoplasmic reticulum" "CAB013722: , HPA013144: " "unprognostic (1.77e-1)" "potential prognostic unfavorable (7.38e-5)" "unprognostic (3.77e-2)" "unprognostic (1.82e-1)" "unprognostic (2.14e-1)" "unprognostic (1.89e-1)" "unprognostic (1.33e-1)" "unprognostic (1.32e-1)" "unprognostic (3.40e-3)" "unprognostic (5.44e-2)" "potential prognostic favorable (2.58e-6)" "unprognostic (7.24e-2)" "unprognostic (5.59e-3)" "unprognostic (3.39e-3)" "unprognostic (1.62e-2)" "unprognostic (1.86e-1)" "unprognostic (2.22e-1)" "unprognostic (1.29e-2)" "unprognostic (9.74e-2)" "unprognostic (1.36e-1)" "unprognostic (6.55e-3)" "unprognostic (2.26e-2)" "potential prognostic unfavorable (8.27e-5)" "unprognostic (1.12e-1)" "unprognostic (1.84e-2)" "unprognostic (2.84e-2)" "unprognostic (4.05e-1)" "unprognostic (1.06e-1)" "unprognostic (2.99e-1)" "unprognostic (5.46e-3)" "unprognostic (2.78e-2)" VARS1 "VARS, VARS2" ENSG00000204394 "Valyl-tRNA synthetase 1" P26640 6 31777518-31795752 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Early spermatids: 160.7;Late spermatids: 211.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Macrophages, Pituitary gland - Somatotropes, Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046710 Approved Supported "Endoplasmic reticulum,Cytosol,Mid piece,Principal piece,End piece" NA NA 100000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 24: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 35 "Endoplasmic reticulum, Cytosol" "Mid piece, Principal piece, End piece" "HPA046710: " "unprognostic (2.89e-1)" "unprognostic (1.71e-1)" "potential prognostic unfavorable (1.75e-4)" "unprognostic (1.66e-1)" "unprognostic (9.88e-2)" "unprognostic (1.75e-2)" "unprognostic (1.39e-2)" "unprognostic (1.11e-1)" "unprognostic (2.32e-1)" "unprognostic (1.05e-3)" "unprognostic (8.48e-2)" "unprognostic (7.04e-2)" "unprognostic (8.60e-2)" "unprognostic (2.06e-2)" "unprognostic (1.65e-2)" "unprognostic (5.72e-3)" "unprognostic (7.65e-2)" "unprognostic (1.33e-1)" "unprognostic (2.87e-1)" "unprognostic (8.02e-2)" "unprognostic (1.54e-1)" "unprognostic (6.75e-2)" "unprognostic (1.05e-2)" "unprognostic (1.74e-1)" "unprognostic (1.96e-1)" "unprognostic (8.03e-2)" "unprognostic (1.33e-1)" "unprognostic (7.61e-2)" "unprognostic (2.08e-1)" VARS2 "DKFZP434L1435, G7a, KIAA1885, VARS2L, VARSL" ENSG00000137411 "Valyl-tRNA synthetase 2, mitochondrial" Q5ST30 6 30914205-30926459 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 20.3;Bergmann glia: 10.7;Brain excitatory neurons: 10.3;Brain inhibitory neurons: 14.1;Distal convoluted tubule cells: 8.5;Ependymal cells: 11.5;Loop of henle epithelial cells: 11.3;Microglia: 9.3;Oligodendrocyte progenitor cells: 16.9;Oligodendrocytes: 10.9;Other brain neurons: 9.8;Papillary tip epithelial cells: 6.0;Podocytes: 9.3;Proximal tubule cells: 22.5;Renal collecting duct intercalated cells: 7.9;Renal collecting duct principal cells: 7.5;Renal connecting tubule cells: 7.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062449, HPA070267" Approved Approved Mitochondria NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 65: Non-specific - Unknown function" "Cluster 102: Non-specific - Mixed function" 13 Mitochondria "HPA062449: , HPA070267: " "unprognostic (1.98e-1)" "unprognostic (6.53e-2)" "unprognostic (2.07e-1)" "unprognostic (3.09e-2)" "unprognostic (1.14e-1)" "unprognostic (7.62e-2)" "unprognostic (8.88e-2)" "potential prognostic favorable (1.97e-4)" "unprognostic (3.89e-2)" "unprognostic (1.48e-1)" "unprognostic (9.48e-3)" "unprognostic (5.77e-2)" "unprognostic (8.05e-2)" "unprognostic (1.04e-1)" "unprognostic (4.12e-2)" "unprognostic (1.93e-2)" "unprognostic (1.47e-1)" "unprognostic (4.47e-2)" "unprognostic (1.52e-1)" "unprognostic (3.69e-1)" "unprognostic (4.85e-2)" "unprognostic (2.27e-1)" "unprognostic (7.40e-2)" "unprognostic (4.01e-2)" "unprognostic (1.05e-1)" "unprognostic (1.25e-1)" "unprognostic (1.84e-1)" "unprognostic (1.08e-1)" "unprognostic (5.02e-1)" "unprognostic (1.36e-1)" "unprognostic (7.40e-2)" VASH1 KIAA1036 ENSG00000071246 "Vasohibin 1" Q7L8A9 14 76761468-76783015 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Cell cycle, Growth arrest" "Carboxypeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 62.8" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 273.3;Early spermatids: 141.2;Granulosa cells: 62.4;Late spermatids: 131.4;Macrophages: 61.3;Microglia: 225.7;Rod photoreceptor cells: 273.3;Sertoli cells: 59.6" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 267.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000653 Uncertain Approved "Nucleoplasm,Centrosome,Basal body,Cytosol" "Secreted to blood" Enzyme NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 1 "Centrosome, Basal body" "Nucleoplasm, Cytosol" "HPA000653: " "unprognostic (1.02e-1)" "unprognostic (2.53e-1)" "unprognostic (1.19e-2)" "unprognostic (1.51e-1)" "unprognostic (4.31e-3)" "unprognostic (1.95e-2)" "unprognostic (3.89e-1)" "unprognostic (7.22e-2)" "unprognostic (2.24e-2)" "unprognostic (2.01e-1)" "potential prognostic favorable (4.68e-4)" "unprognostic (1.26e-3)" "unprognostic (1.52e-2)" "unprognostic (7.36e-3)" "unprognostic (4.98e-2)" "unprognostic (4.20e-2)" "unprognostic (1.12e-2)" "unprognostic (4.54e-2)" "unprognostic (2.17e-1)" "unprognostic (9.52e-2)" "unprognostic (5.28e-2)" "potential prognostic favorable (1.32e-5)" "unprognostic (8.97e-2)" "unprognostic (3.57e-1)" "unprognostic (4.20e-1)" "unprognostic (2.67e-2)" "unprognostic (3.72e-1)" "unprognostic (2.99e-1)" "unprognostic (8.23e-2)" "unprognostic (1.91e-1)" "unprognostic (6.69e-2)" VASH2 FLJ12505 ENSG00000143494 "Vasohibin 2" Q86V25 1 212950520-212992037 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 6.8" "Group enriched" "Detected in many" 4 "Early spermatids: 137.4;Gonadotrophs: 159.7;Late primary spermatocytes: 66.0;Late spermatids: 178.6;pDCs: 65.2" "Cell type enhanced" "Detected in many" "midbrain-derived inhibitory: 91.8" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 11.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 17.7" "Pituitary gland - Gonadotropes, Skeletal muscle - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA045820 Supported Cytosol "Secreted to blood" Enzyme NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 39: Testis - Nuclear processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" Cytosol "HPA045820: " "unprognostic (5.98e-3)" "unprognostic (1.16e-1)" "unprognostic (2.06e-1)" "unprognostic (3.54e-3)" "unprognostic (4.46e-2)" "unprognostic (2.38e-2)" "unprognostic (1.59e-1)" "unprognostic (1.36e-1)" "unprognostic (2.60e-1)" "unprognostic (3.34e-2)" "unprognostic (1.78e-1)" "unprognostic (2.41e-1)" "unprognostic (6.52e-2)" "unprognostic (3.61e-2)" "unprognostic (1.89e-1)" "unprognostic (1.71e-1)" "unprognostic (9.33e-2)" "unprognostic (1.99e-1)" "unprognostic (1.22e-1)" "unprognostic (2.26e-2)" "unprognostic (1.79e-3)" "unprognostic (2.02e-1)" "unprognostic (2.02e-2)" VASN SLITL2 ENSG00000168140 Vasorin Q6EMK4 16 4371848-4383538 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 118.0" "Cell type enhanced" "Detected in some" "Astrocytes: 10.1;Choroid plexus epithelial cells: 7.0;Ependymal cells: 6.8;Loop of henle epithelial cells: 8.1;Papillary tip epithelial cells: 8.6;Podocytes: 96.0;Proximal tubule cells: 8.1;Renal collecting duct intercalated cells: 12.1;Renal collecting duct principal cells: 23.6;Renal connecting tubule cells: 31.1" "Cell type enhanced" "Detected in many" "pericyte: 25.7;vascular associated smooth muscle cell: 52.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Fibroblasts, Prostate - Fibroblasts, Skin - Fibroblasts_2, Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011246, HPA016992" Uncertain Approved Nucleoplasm,Nucleoli,Mitochondria "Secreted - unknown location" "No annotated function" NA Yes 680000000 "Cluster 74: Non-specific - Signal transduction" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 57: Podocytes - Glomerular filtration" 45 Mitochondria "Nucleoplasm, Nucleoli" "HPA011246: , HPA016992: " "unprognostic (7.30e-2)" "unprognostic (1.34e-1)" "unprognostic (4.30e-1)" "unprognostic (2.85e-1)" "unprognostic (3.85e-2)" "unprognostic (2.92e-1)" "unprognostic (1.32e-3)" "potential prognostic unfavorable (8.56e-6)" "unprognostic (1.16e-2)" "unprognostic (6.55e-2)" "potential prognostic unfavorable (7.50e-5)" "unprognostic (2.89e-1)" "unprognostic (1.06e-1)" "unprognostic (1.73e-2)" "unprognostic (1.58e-1)" "unprognostic (1.20e-2)" "unprognostic (3.69e-1)" "unprognostic (1.47e-1)" "unprognostic (2.24e-1)" "unprognostic (3.43e-1)" "unprognostic (1.43e-1)" "unprognostic (3.57e-2)" "unprognostic (1.99e-2)" "unprognostic (2.83e-1)" "unprognostic (2.64e-2)" "unprognostic (1.66e-2)" "unprognostic (1.94e-1)" "unprognostic (2.86e-1)" "unprognostic (1.88e-1)" "unprognostic (2.27e-2)" "unprognostic (4.97e-1)" VASP ENSG00000125753 "Vasodilator stimulated phosphoprotein" P50552 19 45506579-45526989 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 691.0;Megakaryocytes: 1112.7;Neutrophil progenitors: 496.9;Neutrophils: 1519.2;Platelets: 358.2" "Cell type enhanced" "Detected in all" "leukocyte: 56.3;pericyte: 44.7;vascular associated smooth muscle cell: 51.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "granulocytes: 88.1;monocytes: 50.1" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Colon - Smooth muscle cells, Prostate - Smooth muscle cells, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004612, HPA005724" Enhanced Supported "Plasma membrane,Cell Junctions,Focal adhesion sites" NA NA 28000000 "Cluster 45: Eosinophils - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 12: Non-specific - Vasculature" "Cluster 4: Non-specific - Transcription" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 68 "Plasma membrane, Cell Junctions, Focal adhesion sites" "CAB004612: , HPA005724: " "unprognostic (1.14e-1)" "unprognostic (2.94e-1)" "unprognostic (1.74e-1)" "unprognostic (4.79e-2)" "unprognostic (1.42e-2)" "unprognostic (7.32e-2)" "unprognostic (2.13e-1)" "unprognostic (3.62e-2)" "unprognostic (1.23e-2)" "unprognostic (1.20e-1)" "unprognostic (5.85e-3)" "unprognostic (6.40e-2)" "unprognostic (2.66e-1)" "potential prognostic unfavorable (1.48e-6)" "unprognostic (3.84e-2)" "unprognostic (4.02e-2)" "unprognostic (8.00e-2)" "unprognostic (1.30e-3)" "unprognostic (2.70e-1)" "unprognostic (1.09e-2)" "unprognostic (1.14e-1)" "unprognostic (7.38e-3)" "unprognostic (3.25e-1)" "unprognostic (2.77e-2)" "unprognostic (2.89e-1)" "unprognostic (2.42e-1)" "unprognostic (1.94e-1)" "unprognostic (1.46e-1)" "unprognostic (1.12e-1)" "unprognostic (4.06e-2)" "unprognostic (5.53e-2)" VAT1 "FLJ20230, VATI" ENSG00000108828 "Vesicle amine transport 1" Q99536 17 43014607-43025123 "Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 474.2;Hofbauer cells: 199.7;Melanocytes: 192.7" "Cell type enhanced" "Detected in all" "endothelial cell: 51.9" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 615.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "basophil: 104.5" "Lineage enriched" "Detected in all" 5 "granulocytes: 104.5" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Fibroblasts, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045170 Uncertain NA NA 3300000 "Cluster 32: Basophils - Transcription" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 8 "HPA045170: " "unprognostic (1.78e-1)" "unprognostic (8.88e-3)" "unprognostic (2.56e-1)" "unprognostic (2.08e-2)" "unprognostic (4.43e-2)" "potential prognostic unfavorable (8.05e-4)" "unprognostic (2.75e-2)" "unprognostic (9.04e-2)" "unprognostic (7.57e-2)" "unprognostic (3.98e-2)" "potential prognostic favorable (3.10e-8)" "unprognostic (8.28e-3)" "unprognostic (2.71e-1)" "validated prognostic unfavorable (6.93e-4)" "validated prognostic unfavorable (2.06e-5)" "unprognostic (9.15e-3)" "unprognostic (7.51e-2)" "unprognostic (3.43e-2)" "unprognostic (1.14e-1)" "unprognostic (6.88e-3)" "unprognostic (5.84e-3)" "unprognostic (3.05e-3)" "unprognostic (1.37e-1)" "unprognostic (3.99e-1)" "unprognostic (3.20e-2)" "unprognostic (2.08e-2)" "unprognostic (2.29e-1)" "unprognostic (2.08e-2)" "unprognostic (1.33e-1)" "unprognostic (1.79e-1)" "unprognostic (7.99e-2)" VAT1L KIAA1576 ENSG00000171724 "Vesicle amine transport 1 like" Q9HCJ6 16 77788564-77980107 "Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 123.1;choroid plexus: 311.9;retina: 174.9" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 361.7;Bergmann glia: 677.3;Choroid plexus epithelial cells: 1576.6;Müller glia: 206.4;Other brain neurons: 207.8;Retinal horizontal cells: 1662.8;Retinal pigment epithelial cells: 481.7" "Cell type enhanced" "Detected in all" "Bergmann glia: 715.7;choroid plexus epithelial cell: 1061.8" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 12.8;Kidney Chromophobe (TCGA): 15.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Leukemia: 16.5;Neuroblastoma: 17.6" "Colon - Colon enteroendocrine cells, Liver - Hepatic stellate cells, Stomach - Fibroblasts, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044061, CAB046032, HPA061138" Enhanced Approved Cytosol NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 44: Non-specific - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 3 Cytosol "CAB046032: , HPA044061: , HPA061138: " "unprognostic (8.54e-2)" "unprognostic (2.22e-2)" "unprognostic (5.04e-2)" "unprognostic (1.07e-3)" "unprognostic (2.11e-2)" "unprognostic (2.13e-1)" "unprognostic (3.69e-3)" "unprognostic (3.40e-1)" "unprognostic (4.92e-3)" "unprognostic (7.74e-2)" "unprognostic (1.08e-2)" "unprognostic (7.35e-2)" "unprognostic (7.96e-2)" "unprognostic (1.67e-1)" VAV1 VAV ENSG00000141968 "Vav guanine nucleotide exchange factor 1" P15498 19 6772708-6857366 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 51.1;lymphoid tissue: 43.5" "Cell type enhanced" "Detected in many" "B-cells: 101.4;Hofbauer cells: 126.1;Kupffer cells: 101.5;Macrophages: 118.1;Mast cells: 132.0;Microglia: 167.6;monocytes: 178.1;Neutrophil progenitors: 284.4;Neutrophils: 912.5;NK-cells: 113.3;pDCs: 106.3;Thymocytes: 113.5;Tuft cells: 242.1" "Group enriched" "Detected in many" 15 "central nervous system macrophage: 218.1;leukocyte: 143.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 7 "Leukemia: 68.4;lymphoma: 49.5;Myeloma: 68.3" "Adipose visceral - Macrophages, Adrenal gland - Macrophages, Heart muscle - Macrophages, Liver - Kupffer cells, Prostate - T-cells, Skeletal muscle - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001864, HPA005925" Enhanced Approved Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 50 Cytosol "HPA001864: , HPA005925: " "unprognostic (1.35e-1)" "unprognostic (2.31e-1)" "unprognostic (1.30e-1)" "unprognostic (3.25e-1)" "unprognostic (3.13e-1)" "unprognostic (2.21e-1)" "unprognostic (3.24e-2)" "unprognostic (1.00e-1)" "unprognostic (8.38e-3)" "unprognostic (4.15e-1)" "unprognostic (5.66e-2)" "unprognostic (2.64e-1)" "unprognostic (1.58e-1)" "unprognostic (3.56e-1)" "unprognostic (1.12e-1)" "unprognostic (9.17e-2)" "unprognostic (4.01e-2)" "unprognostic (7.87e-2)" "unprognostic (1.43e-1)" "unprognostic (5.34e-3)" "unprognostic (1.13e-1)" "unprognostic (1.31e-1)" "unprognostic (3.01e-3)" "unprognostic (3.79e-2)" "unprognostic (1.36e-1)" "unprognostic (4.80e-2)" "potential prognostic favorable (9.98e-4)" "unprognostic (1.03e-1)" "unprognostic (8.79e-2)" "unprognostic (1.36e-1)" "unprognostic (1.41e-1)" VAV2 ENSG00000160293 "Vav guanine nucleotide exchange factor 2" P52735 9 133761894-133992604 "Plasma proteins, Predicted intracellular proteins, Transporters" Angiogenesis "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Renal collecting duct principal cells: 219.3;Renal connecting tubule cells: 196.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 3.3" "Group enriched" "Detected in many" 22 "B-cells: 3.3;dendritic cells: 1.1;monocytes: 2.0" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Spleen - B-cells (Spleen), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003224 Uncertain Approved Vesicles NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 70: Non-specific - Protein processing" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 20 Vesicles "HPA003224: " "unprognostic (3.54e-2)" "unprognostic (2.81e-2)" "unprognostic (1.43e-2)" "unprognostic (7.85e-2)" "unprognostic (1.26e-1)" "unprognostic (6.22e-3)" "unprognostic (3.17e-1)" "unprognostic (5.41e-2)" "unprognostic (2.89e-1)" "unprognostic (1.97e-1)" "potential prognostic favorable (6.14e-5)" "unprognostic (9.01e-3)" "unprognostic (5.03e-2)" "unprognostic (4.74e-2)" "unprognostic (8.38e-2)" "unprognostic (1.48e-2)" "unprognostic (4.19e-2)" "potential prognostic unfavorable (8.49e-4)" "unprognostic (5.40e-2)" "unprognostic (6.78e-3)" "unprognostic (1.25e-1)" "unprognostic (7.10e-2)" "unprognostic (1.40e-3)" "unprognostic (6.32e-2)" "unprognostic (2.14e-1)" "unprognostic (6.42e-2)" "unprognostic (1.90e-2)" "unprognostic (1.55e-2)" "unprognostic (1.02e-1)" "potential prognostic unfavorable (8.72e-4)" "unprognostic (1.54e-1)" VAV3 ENSG00000134215 "Vav guanine nucleotide exchange factor 3" Q9UKW4 1 107571161-107965180 "Predicted intracellular proteins" Angiogenesis "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 78.4" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 750.2;Distal convoluted tubule cells: 813.3;Hematopoietic stem cells: 1132.5;Lymphatic endothelial cells: 527.1;Neutrophil progenitors: 581.1;Neutrophils: 1072.1;NK-cells: 673.7;Syncytiotrophoblasts: 778.3;Thymocytes: 875.7" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 720.8;choroid plexus epithelial cell: 581.8;midbrain-derived inhibitory: 607.1" "Cancer enhanced" "Detected in all" "Breast Invasive Carcinoma (TCGA): 79.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Breast - Breast glandular cells, Pituitary gland - Thyrotropes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB002012 Uncertain NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 72: Kidney - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 11 "CAB002012: " "unprognostic (1.59e-1)" "unprognostic (2.97e-2)" "unprognostic (2.90e-1)" "unprognostic (9.66e-2)" "unprognostic (3.61e-2)" "unprognostic (6.59e-3)" "unprognostic (4.82e-2)" "potential prognostic unfavorable (1.06e-5)" "unprognostic (2.98e-3)" "unprognostic (1.71e-1)" "potential prognostic favorable (1.42e-10)" "unprognostic (2.13e-2)" "unprognostic (7.86e-2)" "unprognostic (7.45e-2)" "unprognostic (8.46e-2)" "unprognostic (1.48e-1)" "unprognostic (5.93e-3)" "unprognostic (8.90e-2)" "unprognostic (1.02e-2)" "unprognostic (3.82e-2)" "unprognostic (2.13e-1)" "unprognostic (4.20e-1)" "unprognostic (1.27e-2)" "unprognostic (4.10e-1)" "unprognostic (8.83e-3)" "unprognostic (3.73e-1)" "unprognostic (2.81e-2)" "unprognostic (1.22e-1)" "unprognostic (6.61e-2)" "unprognostic (7.93e-2)" "unprognostic (3.71e-2)" VAX1 ENSG00000148704 "Ventral anterior homeobox 1" Q5SQQ9 10 117128521-117138301 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 10 "brain: 4.9" "Cell type enhanced" "Detected in some" "Astrocytes: 1.1;Brain inhibitory neurons: 3.4;Choroid plexus epithelial cells: 5.1;Ependymal cells: 2.6;Late spermatids: 3.1;Oligodendrocytes: 2.3;Other brain neurons: 5.7;Pituitary stem cells: 1.1" "Cell type enhanced" "Detected in some" "CGE interneuron: 7.1;eccentric medium spiny neuron: 11.8;MGE interneuron: 14.7" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 1.8" "Region enhanced" "Detected in many" "hypothalamus: 18.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "Bone cancer: 16.7" "Group enriched" "Detected in some" 6 "basal ganglia: 5.6;hypothalamus: 3.2;olfactory bulb: 1.5" "Low region specificity" "Detected in many" HPA028946 Uncertain Approved "Nucleoplasm,Nucleoli rim" Yes NA "Cluster 78: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" "Nucleoli rim" Nucleoplasm "HPA028946: " "unprognostic (1.67e-1)" "unprognostic (1.22e-1)" VAX2 DRES93 ENSG00000116035 "Ventral anterior homeobox 2" Q9UIW0 2 70900576-70965373 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 12.4;retina: 10.3" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 93.2;Retinal amacrine cells: 17.6;Retinal bipolar cells: 13.3;Retinal ganglion cells: 19.3;Retinal horizontal cells: 24.0;Retinal pigment epithelial cells: 12.8;Rod photoreceptor cells: 82.1" "Group enriched" "Detected in many" 5 "committed oligodendrocyte precursor: 9.9;hippocampal dentate gyrus: 7.1;oligodendrocyte precursor cell: 9.3;upper rhombic lip: 15.9" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 10.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Region enhanced" "Detected in some" "hypothalamus: 4.2" HPA009708 Approved "Nuclear speckles" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 35: Non-specific - DNA binding" "Cluster 5: Rhabdoid - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" 4 "Nuclear speckles" "HPA009708: " "unprognostic (3.38e-3)" "unprognostic (3.12e-1)" "unprognostic (7.57e-3)" "unprognostic (1.58e-1)" "unprognostic (1.25e-2)" "unprognostic (2.95e-2)" "unprognostic (7.82e-2)" "unprognostic (3.05e-2)" "unprognostic (9.46e-3)" "unprognostic (1.65e-1)" "unprognostic (1.37e-1)" "unprognostic (1.00e-1)" "unprognostic (1.21e-1)" "unprognostic (1.06e-1)" "unprognostic (2.43e-1)" VBP1 "PFD3, PFDN3" ENSG00000155959 "VHL binding protein 1" P61758 X 155197007-155239841 "Essential proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Megakaryocytes: 222.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006260, HPA023230" Approved Supported Vesicles,Cytosol NA NA 40000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 76 Cytosol Vesicles "CAB006260: , HPA023230: " "unprognostic (1.55e-1)" "unprognostic (1.60e-3)" "unprognostic (1.61e-2)" "unprognostic (3.04e-2)" "unprognostic (1.42e-1)" "unprognostic (3.41e-2)" "unprognostic (1.47e-1)" "unprognostic (6.20e-2)" "potential prognostic unfavorable (9.45e-4)" "unprognostic (1.25e-2)" "potential prognostic favorable (8.81e-8)" "unprognostic (1.93e-1)" "unprognostic (4.09e-2)" "validated prognostic unfavorable (1.86e-4)" "validated prognostic unfavorable (7.45e-6)" "unprognostic (2.16e-2)" "unprognostic (2.91e-2)" "unprognostic (6.93e-2)" "unprognostic (2.51e-1)" "unprognostic (1.86e-2)" "unprognostic (1.83e-1)" "unprognostic (7.36e-2)" "unprognostic (1.49e-2)" "unprognostic (4.48e-2)" "unprognostic (1.87e-2)" "unprognostic (3.41e-1)" "unprognostic (7.33e-2)" "unprognostic (5.16e-2)" "unprognostic (1.16e-1)" "unprognostic (3.44e-1)" "unprognostic (8.00e-2)" VCAM1 CD106 ENSG00000162692 "Vascular cell adhesion molecule 1" P19320 1 100719742-100739045 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "lymphoid tissue: 366.8" "Group enriched" "Detected in many" 9 "Kupffer cells: 1797.7;Pancreatic duct cells: 641.2" "Cell type enriched" "Detected in some" 4 "endothelial cell: 135.6" "Group enriched" "Detected in all" 7 "Kidney Renal Clear Cell Carcinoma (TCGA): 293.6;Kidney Renal Papillary Cell Carcinoma (TCGA): 234.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder cancer: 34.3;Kidney cancer: 63.3;thyroid cancer: 43.7" "Prostate - Fibroblasts, Spleen - Macrophages, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000154, HPA034796, HPA069867" Enhanced Approved "Cell Junctions" "Secreted to blood" "Cell adhesion" NA NA 624000000 440000000 "Cluster 66: Lymphoid tissue - Immune response" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 10 "Cell Junctions" "CAB000154: , HPA034796: , HPA069867: " "unprognostic (6.75e-3)" "unprognostic (2.69e-1)" "unprognostic (3.12e-1)" "unprognostic (2.24e-3)" "unprognostic (2.44e-1)" "unprognostic (5.88e-2)" "unprognostic (1.99e-1)" "unprognostic (2.03e-1)" "potential prognostic favorable (2.57e-4)" "unprognostic (1.37e-1)" "potential prognostic favorable (1.86e-4)" "unprognostic (3.86e-3)" "unprognostic (1.11e-1)" "unprognostic (5.00e-3)" "unprognostic (7.31e-2)" "unprognostic (8.79e-2)" "unprognostic (1.36e-2)" "unprognostic (2.08e-1)" "unprognostic (2.78e-1)" "unprognostic (7.14e-3)" "unprognostic (8.97e-2)" "unprognostic (1.84e-2)" "unprognostic (1.42e-1)" "unprognostic (7.67e-2)" "unprognostic (2.94e-1)" "unprognostic (6.42e-3)" "unprognostic (1.43e-1)" "unprognostic (4.35e-2)" "unprognostic (1.75e-3)" "unprognostic (1.67e-2)" "unprognostic (1.42e-1)" VCAN "CSPG2, PG-M" ENSG00000038427 Versican P13611 5 83471618-83582303 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 171.7" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 1036.0;Endometrial glandular cells: 530.7;Endometrial stromal cells: 1175.7;Fibroblasts: 494.7;Monocyte progenitors: 1285.0;monocytes: 3415.3;Oligodendrocyte progenitor cells: 2165.4" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 854.8;committed oligodendrocyte precursor: 1174.2;oligodendrocyte precursor cell: 2704.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 240.0;myeloid DC: 89.0" "Group enriched" "Detected in many" 20 "dendritic cells: 89.0;monocytes: 240.0" "Cancer enhanced" "Detected in many" "Kidney cancer: 189.1" "Adrenal gland - Adrenal cortex cells, Prostate - Fibroblasts, Stomach - Fibroblasts, Testis - Peritubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004726, CAB008979" Supported Approved "Vesicles,Mid piece,Principal piece,End piece" "Secreted to blood" "No annotated function" NA NA 39000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 7 "Vesicles, Mid piece, Principal piece, End piece" "CAB008979: , HPA004726: " "unprognostic (4.33e-2)" "unprognostic (1.54e-1)" "unprognostic (7.02e-2)" "unprognostic (4.84e-3)" "unprognostic (2.31e-2)" "unprognostic (5.36e-2)" "unprognostic (2.82e-1)" "unprognostic (2.65e-3)" "unprognostic (3.50e-2)" "unprognostic (3.49e-2)" "unprognostic (2.15e-1)" "unprognostic (1.96e-1)" "unprognostic (1.76e-1)" "unprognostic (1.67e-2)" "unprognostic (6.52e-2)" "unprognostic (6.29e-3)" "unprognostic (4.82e-3)" "unprognostic (2.13e-1)" "unprognostic (6.06e-2)" "unprognostic (2.58e-3)" "potential prognostic unfavorable (1.17e-6)" "unprognostic (5.90e-3)" "unprognostic (3.74e-2)" "unprognostic (1.62e-1)" "unprognostic (3.28e-1)" "unprognostic (7.66e-3)" "unprognostic (2.85e-3)" "potential prognostic unfavorable (7.37e-5)" "unprognostic (1.84e-1)" "unprognostic (2.84e-2)" "unprognostic (1.77e-2)" VCL ENSG00000035403 Vinculin P18206 10 73995193-74121363 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" Actin-binding "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Platelets: 3001.4" "Cell type enhanced" "Detected in all" "vascular associated smooth muscle cell: 474.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002131, CAB002453, HPA063777" Enhanced Enhanced "Focal adhesion sites" NA NA 470000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 52: Non-specific - Mitochondria" "Cluster 51: Secretory epithelial cells - Mixed function" 44 "Focal adhesion sites" "CAB002453: , HPA002131: , HPA063777: " "unprognostic (1.51e-2)" "unprognostic (6.31e-2)" "unprognostic (3.71e-1)" "unprognostic (1.14e-2)" "unprognostic (7.30e-2)" "unprognostic (1.92e-2)" "unprognostic (3.35e-1)" "unprognostic (4.86e-2)" "unprognostic (2.11e-2)" "unprognostic (7.36e-3)" "potential prognostic favorable (5.98e-4)" "unprognostic (1.27e-1)" "unprognostic (9.65e-2)" "unprognostic (5.86e-3)" "unprognostic (6.41e-2)" "unprognostic (2.86e-3)" "unprognostic (3.91e-3)" "unprognostic (8.26e-3)" "unprognostic (1.61e-2)" "unprognostic (3.16e-2)" "unprognostic (2.83e-3)" "potential prognostic unfavorable (6.70e-4)" "unprognostic (1.46e-1)" "unprognostic (9.56e-2)" "unprognostic (2.31e-1)" "unprognostic (2.66e-2)" "unprognostic (5.10e-2)" "unprognostic (3.18e-2)" "unprognostic (2.24e-1)" "unprognostic (1.43e-1)" "unprognostic (2.63e-1)" VCP "CDC48, IBMPFD, p97, TERA" ENSG00000165280 "Valosin containing protein" P55072 9 35053928-35072668 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Autophagy, DNA damage, DNA repair, Transport, Ubl conjugation pathway" Hydrolase "Amyotrophic lateral sclerosis, Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 721.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005593, HPA012728, HPA012814" Supported Supported "Nucleoplasm,Mitotic spindle,Primary cilium tip,Primary cilium transition zone,Basal body,Cytosol" Yes No 66000000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 509 "Nucleoplasm, Cytosol" "Mitotic spindle, Primary cilium tip, Primary cilium transition zone, Basal body" "CAB005593: , HPA012728: , HPA012814: " "unprognostic (3.03e-1)" "unprognostic (6.95e-2)" "unprognostic (1.94e-1)" "unprognostic (8.47e-2)" "unprognostic (7.83e-2)" "unprognostic (1.38e-1)" "unprognostic (1.89e-1)" "unprognostic (3.52e-2)" "unprognostic (3.18e-1)" "unprognostic (9.73e-3)" "unprognostic (2.56e-2)" "unprognostic (6.66e-2)" "unprognostic (1.12e-2)" "potential prognostic unfavorable (9.81e-5)" "unprognostic (9.26e-3)" "unprognostic (5.11e-3)" "potential prognostic unfavorable (8.37e-4)" "unprognostic (2.47e-1)" "unprognostic (3.37e-1)" "unprognostic (4.61e-3)" "unprognostic (1.91e-1)" "unprognostic (1.11e-3)" "unprognostic (8.02e-2)" "unprognostic (1.26e-1)" "unprognostic (3.47e-1)" "unprognostic (1.83e-1)" "unprognostic (3.45e-2)" "unprognostic (8.23e-2)" "unprognostic (3.32e-1)" "unprognostic (6.23e-2)" "unprognostic (1.26e-3)" VCPIP1 "DUBA3, FLJ23132, KIAA1850, VCIP135" ENSG00000175073 "Valosin containing protein interacting protein 1" Q96JH7 8 66628487-66667231 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 19.1" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 109.6;Neutrophils: 161.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023932 Uncertain Uncertain "Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 34: Non-specific - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 43 "Plasma membrane" "Centrosome, Cytosol" "HPA023932: " "potential prognostic favorable (8.71e-4)" "unprognostic (4.61e-2)" "unprognostic (3.48e-1)" "unprognostic (2.15e-2)" "unprognostic (2.15e-1)" "unprognostic (6.27e-2)" "unprognostic (1.67e-1)" "unprognostic (1.56e-1)" "unprognostic (7.91e-2)" "potential prognostic unfavorable (8.51e-4)" "potential prognostic favorable (3.18e-5)" "unprognostic (5.61e-2)" "unprognostic (9.45e-2)" "unprognostic (6.84e-2)" "unprognostic (1.03e-1)" "unprognostic (2.58e-2)" "unprognostic (8.49e-2)" "unprognostic (2.55e-1)" "unprognostic (8.86e-2)" "unprognostic (1.16e-2)" "unprognostic (5.52e-2)" "unprognostic (3.07e-2)" "unprognostic (3.03e-1)" "unprognostic (5.48e-3)" "unprognostic (5.00e-2)" "unprognostic (7.10e-2)" "unprognostic (2.35e-1)" "unprognostic (2.82e-2)" "unprognostic (5.22e-1)" "unprognostic (1.13e-2)" "unprognostic (1.18e-1)" VCPKMT "C14orf138, METTL21D, VCP-KMT" ENSG00000100483 "Valosin containing protein lysine methyltransferase" Q9H867 14 50108632-50116600 "Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 96.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001146, HPA076561" Uncertain Supported Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 24: Neutrophils - Innate immunity signal integration" 7 Cytosol "HPA001146: , HPA076561: " "unprognostic (2.11e-2)" "unprognostic (3.20e-2)" "unprognostic (9.99e-2)" "unprognostic (3.70e-1)" "unprognostic (8.43e-2)" "unprognostic (6.18e-3)" "unprognostic (3.34e-3)" "unprognostic (2.56e-1)" "unprognostic (1.34e-1)" "unprognostic (1.03e-2)" "unprognostic (8.33e-2)" "unprognostic (3.82e-1)" "unprognostic (4.29e-2)" "unprognostic (5.70e-2)" "unprognostic (2.54e-1)" "unprognostic (1.69e-2)" "unprognostic (1.91e-1)" "unprognostic (1.03e-1)" "unprognostic (1.06e-1)" "unprognostic (3.88e-2)" "potential prognostic unfavorable (9.40e-5)" "unprognostic (1.32e-1)" "unprognostic (1.46e-1)" "unprognostic (1.40e-1)" "unprognostic (5.27e-2)" "unprognostic (1.71e-1)" "unprognostic (2.37e-2)" "unprognostic (4.45e-1)" "unprognostic (1.71e-1)" VCX "VCX-10r, VCX-B1, VCX1, VCX10R" ENSG00000182583 "Variable charge X-linked" Q9H320 X 7842262-7844143 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 80 "testis: 29.8" "Group enriched" "Detected in some" 6 "Differentiating spermatogonia: 767.2;Early primary spermatocytes: 1124.0" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 19.5" "HPA044996, HPA049357" Supported NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 106: Spermatogonia - Spermatogonial differentiation" "HPA044996: , HPA049357: " "unprognostic (5.22e-2)" "unprognostic (2.65e-2)" "unprognostic (2.92e-1)" "unprognostic (3.60e-3)" "unprognostic (3.79e-1)" "unprognostic (3.04e-2)" "unprognostic (2.18e-1)" "unprognostic (6.14e-2)" "unprognostic (1.43e-1)" "unprognostic (1.80e-1)" VCX2 VCX-2r ENSG00000177504 "Variable charge X-linked 2" Q9H322 X 8169944-8171267 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 270 "testis: 27.0" "Group enriched" "Detected in some" 6 "Differentiating spermatogonia: 212.9;Early primary spermatocytes: 278.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Skin Cutaneous Melanoma (TCGA): 1.1;Testicular Germ Cell Tumor (TCGA): 1.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "skin cancer: 5.9" "HPA044642, HPA044996, HPA049357" Enhanced NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 69: Skin cancer - ECM organization" "Cluster 106: Spermatogonia - Spermatogonial differentiation" "HPA044642: , HPA044996: , HPA049357: " "unprognostic (7.53e-2)" VCX3A "VCX-8r, VCX-A, VCX3" ENSG00000169059 "Variable charge X-linked 3A" Q9NNX9 X 6533618-6535118 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 130 "testis: 55.4" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 179.3;Early primary spermatocytes: 305.4;Undifferentiated spermatogonia: 65.4" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 28.1;Gastric cancer: 40.1" "HPA044996, HPA049357" Supported NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 106: Spermatogonia - Spermatogonial differentiation" "HPA044996: , HPA049357: " "unprognostic (1.92e-1)" "unprognostic (2.31e-1)" "unprognostic (3.21e-1)" "potential prognostic unfavorable (7.63e-5)" "unprognostic (4.49e-1)" "unprognostic (8.86e-2)" "unprognostic (2.95e-1)" "unprognostic (2.76e-1)" "unprognostic (6.36e-2)" "unprognostic (1.11e-1)" "unprognostic (1.96e-1)" VCX3B VCX-C ENSG00000205642 "Variable charge X-linked 3B" Q9H321 X 8464830-8466510 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 36 "testis: 14.3" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 181.7;Early primary spermatocytes: 326.4;Late primary spermatocytes: 36.3;Undifferentiated spermatogonia: 64.8" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney Chromophobe (TCGA): 2.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 7.6;Gastric cancer: 8.9" "HPA044996, HPA049357" Supported NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 3: Early primary spermatocytes - Early meiosis" "HPA044996: , HPA049357: " "unprognostic (2.72e-1)" "unprognostic (1.65e-1)" "unprognostic (4.55e-1)" "unprognostic (1.21e-1)" VCY "BPY1, VCY1, VCY1A" ENSG00000129864 "Variable charge Y-linked" O14598 Y 13985772-13986473 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 607 "testis: 60.7" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Liver Hepatocellular Carcinoma (TCGA): 4.2;Skin Cutaneous Melanoma (TCGA): 10.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 8 "skin cancer: 17.2" "HPA044996, HPA049357" Supported NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 69: Skin cancer - ECM organization" 1 "HPA044996: , HPA049357: " "unprognostic (8.60e-1)" VCY1B BPY1B ENSG00000129862 "Variable charge Y-linked 1B" O14598 Y 14056227-14056958 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 144 "testis: 64.3" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 8 "Skin Cutaneous Melanoma (TCGA): 29.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "Neuroblastoma: 62.3;skin cancer: 29.9" "HPA044996, HPA049357" Supported NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 69: Skin cancer - ECM organization" 1 "HPA044996: , HPA049357: " "unprognostic (1.59e-1)" "unprognostic (2.09e-1)" "unprognostic (3.98e-2)" VDAC1 "MGC111064, PORIN" ENSG00000213585 "Voltage dependent anion channel 1" P21796 5 133971871-134004975 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Ion transport, Lipid transport, Transport" Porin "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 979.5;tongue: 758.2" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 933.9;Parietal cells: 1168.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005885, HPA030780, CAB072343" Supported NA NA 1400000 "Cluster 33: Non-specific - ATP binding" "Cluster 52: Non-specific - Cellular respiration" "Cluster 23: Choroid plexus - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 97: Non-specific - Cellular respiration" 125 "CAB005885: , CAB072343: , HPA030780: " "unprognostic (6.20e-2)" "potential prognostic unfavorable (1.46e-5)" "unprognostic (8.07e-2)" "unprognostic (3.67e-3)" "unprognostic (8.26e-3)" "unprognostic (1.73e-1)" "unprognostic (3.12e-2)" "unprognostic (1.20e-2)" "potential prognostic unfavorable (4.10e-7)" "unprognostic (1.15e-1)" "potential prognostic favorable (3.75e-6)" "unprognostic (1.74e-1)" "unprognostic (2.10e-1)" "unprognostic (1.87e-3)" "unprognostic (1.48e-3)" "potential prognostic unfavorable (2.07e-5)" "unprognostic (2.91e-3)" "unprognostic (1.40e-1)" "unprognostic (1.13e-1)" "unprognostic (6.59e-2)" "unprognostic (1.40e-1)" "unprognostic (5.48e-3)" "unprognostic (5.26e-1)" "unprognostic (1.59e-1)" "unprognostic (7.30e-2)" "unprognostic (1.06e-2)" "unprognostic (3.61e-1)" "unprognostic (2.75e-1)" "unprognostic (2.09e-1)" "unprognostic (5.83e-3)" "unprognostic (7.43e-2)" VDAC2 ENSG00000165637 "Voltage dependent anion channel 2" P45880 10 75210154-75231448 "Predicted intracellular proteins, Transporters" "Ion transport, Lipid transport, Transport" Porin "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1709.1;Esophageal suprabasal cells: 771.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043475 Enhanced Supported Mitochondria NA NA 340000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 21: Non-specific - Metabolism" "Cluster 52: Non-specific - Mitochondria" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 99 Mitochondria "HPA043475: " "unprognostic (1.85e-3)" "unprognostic (4.54e-3)" "unprognostic (2.55e-1)" "unprognostic (1.28e-2)" "unprognostic (1.66e-1)" "unprognostic (1.77e-1)" "unprognostic (7.18e-2)" "potential prognostic favorable (3.12e-4)" "unprognostic (2.80e-3)" "unprognostic (1.19e-1)" "potential prognostic favorable (1.42e-7)" "unprognostic (4.03e-1)" "unprognostic (6.94e-2)" "validated prognostic unfavorable (1.14e-4)" "validated prognostic unfavorable (1.03e-4)" "potential prognostic unfavorable (8.97e-7)" "unprognostic (1.13e-3)" "unprognostic (3.80e-1)" "unprognostic (5.73e-2)" "unprognostic (2.28e-1)" "unprognostic (1.10e-1)" "unprognostic (6.98e-3)" "unprognostic (1.25e-1)" "unprognostic (1.12e-1)" "unprognostic (2.43e-1)" "unprognostic (3.10e-1)" "unprognostic (5.50e-2)" "unprognostic (1.54e-1)" "unprognostic (2.42e-1)" "unprognostic (2.94e-2)" "unprognostic (1.01e-1)" VDAC3 HD-VDAC3 ENSG00000078668 "Voltage dependent anion channel 3" Q9Y277 8 42391624-42405937 "Plasma proteins, Predicted intracellular proteins" "Ion transport, Transport" Porin "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "heart muscle: 360.7;skeletal muscle: 857.0;tongue: 879.9" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 497.5;Megakaryocytes: 463.6;Platelets: 581.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026864 Uncertain Supported Mitochondria NA NA 1800000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 40: Non-specific - Unknown function" "Cluster 47: Platelets - Hemostasis" 50 Mitochondria "HPA026864: " "unprognostic (5.26e-2)" "unprognostic (4.00e-2)" "unprognostic (9.87e-2)" "unprognostic (1.55e-1)" "unprognostic (9.91e-3)" "unprognostic (6.34e-2)" "unprognostic (1.31e-2)" "unprognostic (8.51e-3)" "unprognostic (1.30e-1)" "potential prognostic unfavorable (4.71e-4)" "potential prognostic favorable (6.16e-6)" "unprognostic (2.13e-1)" "unprognostic (1.84e-1)" "unprognostic (2.15e-2)" "unprognostic (3.57e-1)" "potential prognostic unfavorable (7.85e-4)" "unprognostic (1.25e-1)" "unprognostic (2.57e-2)" "unprognostic (6.51e-3)" "unprognostic (2.12e-1)" "unprognostic (1.36e-2)" "unprognostic (1.97e-1)" "unprognostic (1.92e-1)" "unprognostic (1.09e-2)" "unprognostic (3.29e-2)" "unprognostic (8.07e-2)" "unprognostic (5.53e-2)" "unprognostic (1.70e-2)" "unprognostic (1.95e-1)" "unprognostic (8.08e-3)" "unprognostic (7.66e-2)" VDR "NR1I1, PPP1R163" ENSG00000111424 "Vitamin D receptor" P11473 12 47841537-47943048 "Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors, Transporters" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "parathyroid gland: 221.9" "Cell type enhanced" "Detected in many" "Breast lactating cells: 328.9;cDC: 110.5;Colonocytes: 182.3;Distal convoluted tubule cells: 210.9;Enteric stem cells: 147.4;Enteric transient amplifying cells: 121.9;Enterocytes: 159.5;Epididymal efferent duct absorptive cells: 117.5;Neutrophils: 168.1;Paneth cells: 170.2;Proximal tubule cells: 113.0" "Cell type enriched" "Detected in some" 8 "leukocyte: 11.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 7 "classical monocyte: 3.5;eosinophil: 1.9;intermediate monocyte: 6.5;myeloid DC: 5.1;neutrophil: 6.6;non-classical monocyte: 6.7" "Group enriched" "Detected in many" 8 "dendritic cells: 5.1;granulocytes: 6.6;monocytes: 6.7" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Pituitary gland - Lactotropes" "Region enhanced" "Detected in single" "olfactory bulb: 2.1" "Region enhanced" "Detected in some" "spinal cord: 5.8" "CAB004617, HPA047740, HPA072102" Supported "Nucleoplasm,Intermediate filaments,Cytosol" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 12: Non-specific - Vasculature" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 61 Nucleoplasm "Intermediate filaments, Cytosol" "CAB004617: , HPA047740: , HPA072102: " "potential prognostic favorable (6.06e-4)" "unprognostic (3.22e-2)" "unprognostic (1.47e-1)" "unprognostic (2.04e-2)" "unprognostic (3.81e-1)" "unprognostic (1.67e-2)" "potential prognostic unfavorable (4.25e-4)" "unprognostic (1.57e-2)" "unprognostic (8.25e-2)" "unprognostic (2.76e-1)" "unprognostic (1.54e-2)" "unprognostic (9.02e-2)" "unprognostic (1.68e-2)" "unprognostic (4.41e-2)" "unprognostic (6.06e-2)" "unprognostic (3.23e-1)" "potential prognostic unfavorable (2.06e-4)" "unprognostic (8.72e-3)" "unprognostic (1.36e-2)" "unprognostic (7.09e-2)" "unprognostic (1.40e-3)" "unprognostic (9.50e-3)" "unprognostic (9.44e-2)" "unprognostic (3.30e-2)" "unprognostic (7.66e-2)" "unprognostic (1.01e-1)" "unprognostic (2.49e-1)" "unprognostic (1.88e-1)" "unprognostic (5.12e-2)" "unprognostic (1.33e-1)" "unprognostic (3.41e-1)" VEGFA "VEGF, VEGF-A, VPF" ENSG00000112715 "Vascular endothelial growth factor A" P15692 6 43770184-43786487 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 342.6;Foveolar cells: 301.1;Müller glia: 301.1;Podocytes: 1272.4;Prostatic glandular cells: 358.5" "Cell type enhanced" "Detected in all" "astrocyte: 127.8;oligodendrocyte precursor cell: 116.3" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 667.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Kidney - Podocytes, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005429, CAB039240, HPA069116, CAB069907" Supported "Secreted to blood" "Growth factor" NA NA 562000 26000 "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 15: Kidney cancer - Membrane components" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 24 "CAB005429: , CAB039240: , CAB069907: , HPA069116: " "unprognostic (2.38e-1)" "unprognostic (1.70e-2)" "unprognostic (7.20e-2)" "potential prognostic unfavorable (8.18e-4)" "unprognostic (2.97e-3)" "unprognostic (2.69e-1)" "unprognostic (6.95e-3)" "potential prognostic unfavorable (1.56e-4)" "unprognostic (1.22e-1)" "unprognostic (4.35e-2)" "potential prognostic favorable (2.20e-4)" "unprognostic (3.93e-3)" "potential prognostic unfavorable (4.09e-5)" "potential prognostic unfavorable (1.16e-4)" "unprognostic (3.40e-3)" "unprognostic (1.24e-2)" "potential prognostic unfavorable (7.04e-4)" "unprognostic (1.25e-1)" "unprognostic (8.42e-2)" "unprognostic (2.85e-1)" "unprognostic (1.10e-1)" "unprognostic (1.32e-2)" "unprognostic (2.58e-3)" "unprognostic (8.45e-3)" "unprognostic (5.90e-3)" "unprognostic (1.28e-1)" "unprognostic (9.42e-2)" "unprognostic (3.35e-1)" "unprognostic (2.32e-1)" "unprognostic (1.35e-1)" "unprognostic (4.26e-2)" VEGFB "VEGFL, VRF" ENSG00000173511 "Vascular endothelial growth factor B" P49765 11 64234584-64239264 "Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "pDCs: 310.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 10 "plasmacytoid DC: 30.5" "Lineage enriched" "Detected in many" 10 "dendritic cells: 30.5" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" "Growth factor" NA NA 186000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 74: Non-specific - Signal transduction" "Cluster 19: Astrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 3 "unprognostic (2.58e-1)" "unprognostic (1.65e-1)" "unprognostic (2.00e-1)" "unprognostic (2.07e-1)" "unprognostic (1.28e-2)" "unprognostic (9.85e-2)" "unprognostic (2.82e-3)" "unprognostic (3.18e-2)" "unprognostic (1.23e-1)" "unprognostic (3.32e-2)" "unprognostic (1.58e-3)" "unprognostic (1.26e-1)" "unprognostic (1.39e-2)" "unprognostic (2.99e-2)" "unprognostic (4.45e-3)" "unprognostic (2.92e-1)" "unprognostic (1.56e-1)" "unprognostic (9.06e-3)" "unprognostic (2.42e-1)" "unprognostic (9.74e-2)" "unprognostic (2.04e-1)" "unprognostic (4.11e-3)" "unprognostic (2.66e-1)" "unprognostic (1.16e-1)" "unprognostic (1.62e-1)" "unprognostic (2.16e-1)" "unprognostic (1.51e-1)" "unprognostic (3.84e-3)" "unprognostic (6.44e-2)" "unprognostic (6.10e-3)" "unprognostic (1.28e-1)" VEGFC "VEGF-C, VRP" ENSG00000150630 "Vascular endothelial growth factor C" P49767 4 176683538-176792922 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted secreted proteins, RAS pathway related proteins, Transporters" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 53.4;Ependymal cells: 73.6;Epicardial cells: 127.4;Fibro-adipogenic progenitors: 86.4;Mesothelial cells: 70.7;Platelets: 100.2;Renal connecting tubule cells: 52.8;Retinal horizontal cells: 82.1;Salivary duct cells: 60.1;Vascular endothelial cells: 160.3" "Cell type enhanced" "Detected in many" "endothelial cell: 210.0;ependymal cell: 63.1" "Cancer enhanced" "Detected in all" "Thyroid Carcinoma (TCGA): 35.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells, Liver - Hepatic stellate cells, Pituitary gland - Endothelial cells, Spleen - Fibroblasts_1, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" "Growth factor" NA NA 383000 210000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 19: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 4 "unprognostic (2.41e-1)" "unprognostic (2.09e-1)" "unprognostic (4.51e-1)" "unprognostic (6.67e-2)" "unprognostic (1.04e-2)" "unprognostic (4.93e-2)" "unprognostic (3.67e-3)" "unprognostic (4.70e-2)" "unprognostic (3.65e-3)" "unprognostic (2.47e-2)" "unprognostic (7.47e-2)" "unprognostic (1.15e-1)" "unprognostic (1.50e-1)" "unprognostic (2.49e-1)" "unprognostic (1.86e-2)" "potential prognostic unfavorable (7.50e-9)" "unprognostic (1.13e-2)" "unprognostic (1.11e-2)" "unprognostic (5.69e-2)" "unprognostic (1.27e-1)" "unprognostic (2.51e-1)" "unprognostic (3.68e-1)" "unprognostic (7.55e-2)" "unprognostic (2.43e-1)" "unprognostic (1.58e-3)" "unprognostic (2.64e-2)" "unprognostic (5.22e-1)" "unprognostic (5.81e-3)" "unprognostic (2.14e-1)" "unprognostic (2.11e-1)" "unprognostic (2.57e-2)" VEGFD "FIGF, VEGF-D" ENSG00000165197 "Vascular endothelial growth factor D" O43915 X 15345596-15384413 "Cancer-related genes, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 40.1" "Cell type enhanced" "Detected in many" "Fibro-adipogenic progenitors: 28.1;Fibroblasts: 66.6;Myonuclei: 102.9;Other brain neurons: 21.8;Retinal ganglion cells: 19.3" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Liver Hepatocellular Carcinoma (TCGA): 3.0;Lung Adenocarcinoma (TCGA): 3.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Neuroblastoma: 7.8" "Lung - Fibroblasts_1, Stomach - Fibroblasts" "Group enriched" "Detected in many" 4 "amygdala: 2.1;cerebral cortex: 3.5;hippocampal formation: 3.3;white matter: 2.6" "Low region specificity" "Detected in single" HPA027342 Uncertain "Secreted to blood" "Growth factor" NA NA 592000 220000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 24: Neurons - Mixed function" "Cluster 61: BICR 18 - Protein kinases" "Cluster 108: Fibroblasts - ECM organization" 21 "HPA027342: " "potential prognostic unfavorable (2.12e-4)" "unprognostic (3.09e-2)" "potential prognostic favorable (3.04e-5)" "unprognostic (1.08e-2)" "unprognostic (1.19e-2)" "unprognostic (1.02e-1)" VENTX "HPX42B, VENTX2" ENSG00000151650 "VENT homeobox" O95231 10 133237855-133241928 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "cDC: 12.1;Macrophages: 14.6;Microglia: 5.9;monocytes: 14.7" "Cell type enriched" "Detected in some" 4 "central nervous system macrophage: 9.3" "Cancer enriched" "Detected in many" 14 "Testicular Germ Cell Tumor (TCGA): 54.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 7 "dendritic cells: 1.8;granulocytes: 1.7;monocytes: 3.2" "Cancer enhanced" "Detected in some" "Leukemia: 1.8;testis cancer: 1.2" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Kidney - Macrophages, Minor Salivary Gland - Macrophages, Skeletal muscle - Macrophages, Thyroid gland - Macrophages" HPA050955 Uncertain Approved "Nucleoli fibrillar center" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 5: Spleen - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 66 "Nucleoli fibrillar center" "HPA050955: " "unprognostic (8.27e-2)" "unprognostic (2.55e-3)" "unprognostic (9.53e-2)" "unprognostic (1.14e-1)" "unprognostic (1.15e-2)" "unprognostic (1.72e-1)" "validated prognostic unfavorable (2.92e-4)" "validated prognostic unfavorable (3.99e-6)" "unprognostic (9.98e-3)" "unprognostic (6.03e-3)" "unprognostic (2.53e-1)" "unprognostic (2.92e-2)" "unprognostic (9.87e-2)" "unprognostic (3.28e-1)" "unprognostic (3.79e-2)" "unprognostic (5.29e-1)" VEPH1 "FLJ12604, KIAA1692" ENSG00000197415 "Ventricular zone expressed PH domain containing 1" Q14D04 3 157259742-157533619 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 19.1;kidney: 25.2;lung: 27.7" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 292.0;Alveolar cells type 1: 214.8;Alveolar cells type 2: 383.9;Choroid plexus epithelial cells: 168.2;Early spermatids: 170.8;Late spermatids: 151.4;Neutrophil progenitors: 158.0;Pituitary stem cells: 947.0;Renal collecting duct principal cells: 228.6;Renal connecting tubule cells: 208.9;Retinal pigment epithelial cells: 153.5;Transitional alveolar cells: 236.0" "Group enriched" "Detected in many" 5 "choroid plexus epithelial cell: 140.1;ependymal cell: 35.2;lower rhombic lip: 59.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "choroid plexus: 24.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary gland ductal cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA026645 Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 37: Neutrophil progenitors - Granulopoiesis" "Nucleoplasm, Nucleoli, Cytosol" "HPA026645: " "unprognostic (2.02e-1)" "unprognostic (2.04e-2)" "unprognostic (3.24e-1)" "unprognostic (1.37e-1)" "unprognostic (5.07e-3)" "unprognostic (7.75e-2)" "unprognostic (1.11e-2)" "unprognostic (2.19e-1)" "potential prognostic favorable (1.04e-6)" "unprognostic (3.00e-1)" "unprognostic (4.82e-2)" "unprognostic (1.12e-3)" "unprognostic (7.32e-2)" "unprognostic (1.54e-1)" "unprognostic (1.02e-1)" "unprognostic (1.35e-2)" "unprognostic (7.07e-2)" "unprognostic (2.71e-3)" "unprognostic (2.88e-1)" "validated prognostic unfavorable (7.92e-4)" "validated prognostic unfavorable (9.39e-4)" "unprognostic (7.19e-2)" "unprognostic (5.31e-2)" "unprognostic (4.48e-2)" "unprognostic (5.51e-2)" VEZF1 "DB1, ZNF161" ENSG00000136451 "Vascular endothelial zinc finger 1" Q14119 17 57971547-57988259 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skin - Endothelial cells, Spleen - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027520, HPA048315" Uncertain Enhanced Nucleoplasm NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 40: Non-specific - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 27: Breast cancer - Unknown function" "Cluster 17: Non-specific - RNA processing" 42 Nucleoplasm "HPA027520: , HPA048315: " "unprognostic (1.53e-3)" "unprognostic (2.16e-2)" "unprognostic (8.08e-2)" "unprognostic (2.93e-1)" "unprognostic (1.79e-1)" "unprognostic (7.79e-2)" "unprognostic (1.89e-1)" "unprognostic (9.87e-2)" "unprognostic (1.30e-1)" "potential prognostic unfavorable (7.77e-4)" "validated prognostic favorable (8.97e-7)" "validated prognostic favorable (7.10e-4)" "unprognostic (3.21e-1)" "potential prognostic unfavorable (1.52e-4)" "unprognostic (1.31e-2)" "unprognostic (1.71e-1)" "potential prognostic unfavorable (3.83e-4)" "unprognostic (2.30e-1)" "unprognostic (3.42e-3)" "unprognostic (2.05e-2)" "unprognostic (1.05e-1)" "unprognostic (6.31e-2)" "unprognostic (2.20e-1)" "unprognostic (1.42e-1)" "unprognostic (3.53e-2)" "unprognostic (6.17e-2)" "unprognostic (3.10e-1)" "unprognostic (8.64e-2)" "unprognostic (1.88e-1)" "unprognostic (2.42e-2)" "unprognostic (1.84e-1)" VEZT DKFZP761C241 ENSG00000028203 "Vezatin, adherens junctions transmembrane protein" Q9HBM0 12 95217746-95302799 "Essential proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004811, HPA017066" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 2: Neurons - Nucleosome" "Cluster 38: Non-specific - Transcription" "Cluster 79: Photoreceptor cells - Phototransduction" 9 Nucleoplasm Cytosol "HPA004811: , HPA017066: " "unprognostic (1.00e-1)" "unprognostic (1.52e-1)" "unprognostic (2.68e-1)" "unprognostic (8.77e-3)" "unprognostic (1.67e-1)" "unprognostic (6.22e-2)" "unprognostic (1.93e-1)" "unprognostic (1.05e-2)" "unprognostic (2.42e-1)" "unprognostic (3.16e-1)" "unprognostic (4.33e-2)" "unprognostic (5.69e-2)" "unprognostic (5.60e-2)" "unprognostic (1.39e-3)" "unprognostic (2.02e-1)" "unprognostic (1.18e-1)" "unprognostic (6.06e-3)" "unprognostic (3.37e-1)" "unprognostic (1.78e-1)" "unprognostic (3.94e-2)" "potential prognostic unfavorable (4.98e-4)" "unprognostic (1.92e-1)" "unprognostic (1.65e-2)" "unprognostic (1.30e-3)" "unprognostic (5.87e-2)" "unprognostic (4.59e-2)" "unprognostic (1.55e-1)" "unprognostic (3.42e-3)" "unprognostic (2.45e-1)" "unprognostic (1.36e-1)" "unprognostic (4.64e-2)" VGF "SCG7, SgVII" ENSG00000128564 "VGF nerve growth factor inducible" O15240 7 101162509-101165569 "Plasma proteins, Predicted secreted proteins" "Antibiotic, Antimicrobial, Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 143.5;pituitary gland: 91.1" "Cell type enriched" "Detected in some" 8 "Pancreatic islet cells: 910.9" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in many" 6 "Skin Cutaneous Melanoma (TCGA): 472.9" "Region enriched" "Detected in all" 6 "hypothalamus: 2693.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 141.0;skin cancer: 234.3" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Thyroid gland - Parafollicular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055177, HPA072505" Enhanced Enhanced "Golgi apparatus,Vesicles" "Secreted to blood" "Growth factor" NA NA 1270000 1800000 "Cluster 78: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 16 "Golgi apparatus, Vesicles" "HPA055177: , HPA072505: " "unprognostic (2.35e-2)" "unprognostic (2.12e-2)" "unprognostic (2.09e-1)" "unprognostic (6.75e-3)" "unprognostic (3.12e-2)" "potential prognostic unfavorable (6.57e-4)" "unprognostic (2.22e-2)" "unprognostic (6.16e-1)" "unprognostic (4.87e-2)" "potential prognostic unfavorable (1.18e-5)" "unprognostic (1.71e-2)" "unprognostic (3.65e-2)" "unprognostic (1.68e-1)" "potential prognostic favorable (7.93e-4)" "unprognostic (1.08e-1)" "potential prognostic unfavorable (4.45e-6)" "unprognostic (4.52e-2)" "unprognostic (3.05e-1)" "unprognostic (4.78e-3)" "unprognostic (3.97e-1)" "unprognostic (1.13e-1)" "unprognostic (1.45e-2)" "unprognostic (6.30e-2)" VGLL1 "TDU, TONDU" ENSG00000102243 "Vestigial like family member 1" Q99990 X 136532215-136556807 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "placenta: 191.5" "Group enriched" "Detected in some" 28 "Cytotrophoblasts: 1559.2;Extravillous trophoblasts: 628.2;Migrating cytotrophoblasts: 1156.8;Syncytiotrophoblasts: 2022.1" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Bladder Urothelial Carcinoma (TCGA): 170.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder cancer: 83.9" "Skin - Hair cortex cells, Skin - Inner root sheath cells" "Not detected" "Not detected" "HPA042403, HPA064616" Supported Supported Nucleoplasm NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 17 Nucleoplasm "HPA042403: , HPA064616: " "unprognostic (5.06e-2)" "unprognostic (2.42e-1)" "unprognostic (3.77e-1)" "unprognostic (7.54e-3)" "unprognostic (5.16e-2)" "unprognostic (3.32e-1)" "unprognostic (3.60e-1)" "unprognostic (7.26e-2)" "unprognostic (1.12e-1)" "unprognostic (3.49e-2)" "unprognostic (1.66e-2)" "unprognostic (2.74e-1)" "unprognostic (1.05e-3)" "unprognostic (5.74e-3)" "unprognostic (1.42e-2)" "unprognostic (5.63e-2)" "unprognostic (2.86e-1)" "unprognostic (1.47e-2)" "unprognostic (1.85e-2)" VGLL2 ENSG00000170162 "Vestigial like family member 2" Q8N8G2 6 117265558-117273565 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "skeletal muscle: 121.3" "Group enriched" "Detected in some" 9 "Myonuclei: 51.6;Thymic myoid cells: 21.8" "Cell type enhanced" "Detected in single" "cerebellar inhibitory: 1.3" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 1.1;Lung Adenocarcinoma (TCGA): 1.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "ovarian cancer: 19.3;Sarcoma: 10.2" "Skeletal muscle - Skeletal myocytes, Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 49: Hindbrain - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 1 "unprognostic (4.46e-2)" "unprognostic (1.14e-2)" "unprognostic (5.68e-1)" VGLL3 VGL-3 ENSG00000206538 "Vestigial like family member 3" A8MV65 3 86876388-86991149 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 37.7" "Cell type enhanced" "Detected in many" "Early spermatids: 234.9;Extravillous trophoblasts: 490.1;Fibro-adipogenic progenitors: 121.2;Hepatic stellate cells: 122.6;Late spermatids: 153.5;Leydig cells: 268.6;Mesothelial cells: 171.1;Migrating cytotrophoblasts: 195.3;Myosatellite cells: 127.7;Pancreatic duct cells: 128.0;Peritubular myoid cells: 253.8;Schwann cells: 213.4;Syncytiotrophoblasts: 261.5;Urothelial cells: 298.4" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 49.2;vascular associated smooth muscle cell: 58.9" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 12.0;Prostate Adenocarcinoma (TCGA): 13.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 59.0" "Spleen - Fibroblasts_1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA054983 Approved Approved Nucleoli,Cytosol NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 69: Urothelial cells - Basic cellular functions" 1 "Nucleoli, Cytosol" "HPA054983: " "unprognostic (1.14e-2)" "unprognostic (1.19e-1)" "unprognostic (4.13e-2)" "unprognostic (2.87e-3)" "unprognostic (1.86e-2)" "unprognostic (1.09e-1)" "unprognostic (8.14e-3)" "unprognostic (1.36e-1)" "unprognostic (1.91e-2)" "unprognostic (5.91e-2)" "unprognostic (6.91e-2)" "unprognostic (2.47e-1)" "unprognostic (1.65e-2)" "unprognostic (7.45e-2)" "unprognostic (1.85e-2)" "unprognostic (5.96e-2)" "unprognostic (2.23e-3)" "unprognostic (1.49e-1)" "unprognostic (9.23e-2)" "unprognostic (7.26e-2)" "unprognostic (7.60e-3)" "unprognostic (2.07e-1)" "unprognostic (2.22e-1)" VGLL4 KIAA0121 ENSG00000144560 "Vestigial like family member 4" Q14135 3 11556069-11771350 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Choroid plexus epithelial cells: 718.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Fibroblasts_1, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038225, HPA038614" Approved Approved "Nucleoplasm,Nucleoli fibrillar center" NA No "Cluster 5: Non-specific - Cell proliferation" "Cluster 75: Ovary - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 15 "Nucleoli fibrillar center" Nucleoplasm "HPA038225: , HPA038614: " "unprognostic (2.14e-2)" "unprognostic (1.41e-2)" "unprognostic (1.10e-1)" "unprognostic (1.31e-3)" "unprognostic (5.14e-2)" "unprognostic (9.24e-2)" "unprognostic (3.17e-1)" "unprognostic (4.58e-2)" "unprognostic (1.87e-1)" "unprognostic (1.80e-2)" "unprognostic (1.97e-3)" "unprognostic (6.14e-3)" "potential prognostic favorable (5.07e-4)" "potential prognostic unfavorable (4.98e-4)" "unprognostic (1.40e-2)" "unprognostic (8.35e-2)" "potential prognostic unfavorable (1.17e-4)" "unprognostic (2.07e-1)" "unprognostic (3.30e-2)" "unprognostic (3.65e-3)" "potential prognostic unfavorable (5.48e-4)" "unprognostic (4.52e-3)" "unprognostic (1.42e-1)" "unprognostic (1.88e-1)" "unprognostic (1.88e-2)" "unprognostic (3.26e-3)" "unprognostic (1.82e-1)" "unprognostic (2.12e-1)" "unprognostic (1.26e-1)" "unprognostic (1.08e-2)" "unprognostic (7.62e-2)" VHL VHL1 ENSG00000134086 "Von Hippel-Lindau tumor suppressor" P40337 3 10141778-10153667 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Cancer-related genes, Congenital erythrocytosis, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031631, HPA031632, HPA068954" Approved Enhanced "Nucleoplasm,Microtubules,Primary cilium,Primary cilium tip,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 34: Non-specific - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 153 Nucleoplasm "Microtubules, Primary cilium, Primary cilium tip, Cytosol" "HPA031631: , HPA031632: , HPA068954: " "unprognostic (5.51e-3)" "unprognostic (1.26e-3)" "unprognostic (8.18e-2)" "unprognostic (4.43e-3)" "unprognostic (4.47e-2)" "unprognostic (1.65e-1)" "unprognostic (2.74e-1)" "unprognostic (1.00e-1)" "unprognostic (5.13e-2)" "unprognostic (3.57e-3)" "unprognostic (1.66e-1)" "unprognostic (8.11e-2)" "unprognostic (1.55e-1)" "potential prognostic unfavorable (6.76e-9)" "unprognostic (5.46e-3)" "unprognostic (1.49e-1)" "unprognostic (1.24e-2)" "unprognostic (2.27e-1)" "unprognostic (5.51e-3)" "unprognostic (1.28e-2)" "unprognostic (1.17e-2)" "unprognostic (7.71e-3)" "unprognostic (2.00e-2)" "unprognostic (8.81e-3)" "potential prognostic favorable (8.78e-4)" "unprognostic (9.08e-2)" "unprognostic (1.40e-1)" "unprognostic (5.46e-3)" "unprognostic (1.55e-1)" "unprognostic (3.51e-3)" "unprognostic (1.67e-2)" VHLL "VHLP, VLP" ENSG00000189030 "VHL like" Q6RSH7 1 156298624-156299307 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 35: Non-specific - DNA binding" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 5 VIL1 "D2S1471, VIL" ENSG00000127831 "Villin 1" P09327 2 218419121-218453295 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Actin capping, Actin-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "intestine: 410.7" "Cell type enhanced" "Detected in many" "Colonocytes: 251.7;Enteric stem cells: 167.2;Enteric transient amplifying cells: 180.1;Enterocytes: 558.6;Epididymal efferent duct absorptive cells: 62.3;Gastric progenitor cells: 105.1;Goblet cells: 160.1;Neuroendocrine cells: 128.7;Paneth cells: 131.5;Tuft cells: 149.9" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Colon Adenocarcinoma (TCGA): 245.1;Rectum Adenocarcinoma (TCGA): 254.5;Stomach Adenocarcinoma (TCGA): 96.1" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "neutrophil: 1.3" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.3" "Group enriched" "Detected in many" 5 "Bile duct cancer: 128.5;colorectal cancer: 290.7;Gastric cancer: 138.2;liver cancer: 154.1" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Skin - Keratinocyte (granular), Testis - Late spermatids" "Low region specificity" "Detected in single" "Not detected" "Not detected" "CAB002452, HPA006884, HPA006885" Enhanced Enhanced "Plasma membrane" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 77: Intestine - Digestion" "Cluster 15: Non-specific - Transcription" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 1: Enterocytes - Absorption and Digestion" 3 "Plasma membrane" "CAB002452: , HPA006884: , HPA006885: " "unprognostic (1.41e-1)" "potential prognostic favorable (2.94e-4)" "unprognostic (6.10e-2)" "unprognostic (4.35e-2)" "validated prognostic favorable (1.25e-6)" "validated prognostic favorable (1.75e-4)" "unprognostic (2.43e-2)" "unprognostic (1.16e-1)" "potential prognostic unfavorable (4.14e-4)" "unprognostic (3.14e-1)" "unprognostic (2.58e-2)" "unprognostic (2.98e-2)" "unprognostic (7.84e-2)" "unprognostic (2.29e-1)" "unprognostic (6.39e-2)" "unprognostic (2.86e-1)" "unprognostic (2.90e-1)" "unprognostic (2.75e-2)" "unprognostic (4.36e-2)" "unprognostic (6.53e-2)" "unprognostic (3.40e-1)" "unprognostic (1.97e-1)" "unprognostic (1.18e-2)" VILL ENSG00000136059 "Villin like" O15195 3 37988059-38007188 "Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "intestine: 51.7;stomach 1: 82.4" "Cell type enhanced" "Detected in many" "Colonocytes: 187.9;Enterocytes: 180.3;Foveolar cells: 431.5;Goblet cells: 113.2;Respiratory secretory cells: 78.2;Retinal pigment epithelial cells: 102.3" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Pancreatic Adenocarcinoma (TCGA): 80.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 57.2" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA035675 Enhanced Approved "Golgi apparatus,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 77: Intestine - Digestion" "Cluster 51: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 68: Foveolar cells - Mucosal defense" "Golgi apparatus, Cytosol" "HPA035675: " "potential prognostic favorable (7.56e-4)" "unprognostic (8.71e-2)" "unprognostic (1.29e-2)" "unprognostic (6.82e-2)" "unprognostic (2.78e-1)" "unprognostic (2.51e-2)" "potential prognostic unfavorable (9.93e-5)" "unprognostic (6.00e-3)" "potential prognostic favorable (4.29e-5)" "unprognostic (2.44e-2)" "unprognostic (4.64e-2)" "unprognostic (1.71e-1)" "unprognostic (5.49e-2)" "unprognostic (4.07e-2)" "unprognostic (1.57e-3)" "unprognostic (1.71e-1)" "unprognostic (6.87e-2)" "potential prognostic favorable (3.60e-4)" "unprognostic (1.00e-1)" "unprognostic (1.95e-3)" "unprognostic (1.83e-3)" "unprognostic (1.04e-1)" "unprognostic (3.76e-2)" "unprognostic (2.02e-3)" "unprognostic (1.29e-1)" "unprognostic (3.79e-2)" "unprognostic (9.01e-2)" "unprognostic (4.29e-2)" "unprognostic (2.01e-1)" "unprognostic (7.73e-2)" VIM ENSG00000026025 Vimentin P08670 10 17228241-17237593 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 5524.1" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 5626.0;Fibroblasts: 3422.6;Hepatic stellate cells: 3182.2;Kupffer cells: 3366.8;Leydig cells: 2915.5;Lymphatic endothelial cells: 4529.6;Mast cells: 5504.7;Melanocytes: 4296.4;Monocyte progenitors: 2758.0;monocytes: 3632.4;Müller glia: 6803.6;Ovarian stromal cells: 4974.3;Schwann cells: 5554.2;Vascular smooth muscle cells: 4340.1" "Cell type enhanced" "Detected in many" "endothelial cell: 578.6;vascular associated smooth muscle cell: 1423.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Fibroblasts, Prostate - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000080, HPA001762, CAB058687" Enhanced Supported "Intermediate filaments" NA NA 37000000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 12: Non-specific - Vasculature" "Cluster 72: Neuronal - Signal transduction" "Cluster 97: Non-specific - Cellular respiration" 272 "Intermediate filaments" "CAB000080: , CAB058687: , HPA001762: " "unprognostic (1.22e-1)" "unprognostic (2.32e-2)" "unprognostic (2.64e-1)" "unprognostic (2.34e-1)" "unprognostic (5.86e-2)" "unprognostic (5.08e-2)" "unprognostic (7.51e-2)" "unprognostic (7.35e-3)" "unprognostic (2.02e-1)" "unprognostic (2.84e-1)" "unprognostic (5.94e-3)" "unprognostic (2.29e-2)" "unprognostic (1.73e-1)" "unprognostic (2.47e-1)" "unprognostic (3.76e-1)" "unprognostic (1.44e-1)" "unprognostic (3.07e-3)" "unprognostic (6.59e-2)" "unprognostic (9.82e-2)" "unprognostic (1.31e-1)" "unprognostic (2.34e-1)" "unprognostic (6.66e-2)" "unprognostic (3.03e-1)" "unprognostic (5.11e-2)" "unprognostic (3.09e-2)" "unprognostic (2.14e-2)" "unprognostic (2.70e-1)" "unprognostic (1.93e-3)" "unprognostic (4.79e-2)" "unprognostic (2.70e-2)" "unprognostic (1.19e-1)" VIP ENSG00000146469 "Vasoactive intestinal peptide" P01282 6 152750797-152759765 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" Hormone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 67.6;lymphoid tissue: 146.8" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 3.5;Brain inhibitory neurons: 52.9;Early spermatids: 20.5;Late spermatids: 10.1;Lymphatic endothelial cells: 3.5;Other brain neurons: 12.6;Vascular endothelial cells: 3.9" "Cell type enriched" "Detected in many" 42 "CGE interneuron: 396.1" "Group enriched" "Detected in some" 4 "Colon Adenocarcinoma (TCGA): 5.7;Pancreatic Adenocarcinoma (TCGA): 6.6;Rectum Adenocarcinoma (TCGA): 10.2;Stomach Adenocarcinoma (TCGA): 4.2" "Group enriched" "Detected in many" 4 "hypothalamus: 51.9;midbrain: 78.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Neuroblastoma: 131.7" "Adipose visceral - Endothelial cells, Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Liver - Vascular endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA017324, CAB018649, HPA072701, CAB079780" Supported Supported Approved "Endoplasmic reticulum" "Secreted to blood" Hormone NA NA 122000 "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 70: DU4475 - Unknown function" "Cluster 109: Neurons - Neuronal signaling" 1 "Endoplasmic reticulum" "CAB018649: , CAB079780: , HPA017324: , HPA072701: " "unprognostic (1.39e-2)" "unprognostic (1.11e-1)" "unprognostic (1.10e-2)" "unprognostic (5.36e-2)" "unprognostic (9.32e-2)" "unprognostic (1.34e-2)" "unprognostic (2.35e-1)" "unprognostic (2.23e-1)" "unprognostic (1.62e-2)" "unprognostic (9.38e-3)" "unprognostic (3.97e-2)" VIPAS39 "C14orf133, hSPE-39, SPE-39, SPE39, VIPAR, VPS16B" ENSG00000151445 "VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog" Q9H9C1 14 77426675-77457952 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Protein transport, Spermatogenesis, Transcription, Transcription regulation, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Sertoli cells: 76.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003589, HPA003593" Approved NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 7: Non-specific - Transcription" 10 "HPA003589: , HPA003593: " "unprognostic (6.19e-3)" "unprognostic (6.22e-2)" "unprognostic (2.15e-1)" "unprognostic (4.10e-2)" "unprognostic (3.39e-2)" "unprognostic (2.08e-2)" "unprognostic (5.24e-3)" "unprognostic (1.13e-1)" "potential prognostic unfavorable (2.77e-4)" "potential prognostic favorable (1.72e-5)" "unprognostic (2.20e-2)" "unprognostic (2.82e-3)" "potential prognostic unfavorable (1.19e-7)" "unprognostic (1.51e-1)" "unprognostic (2.31e-1)" "unprognostic (1.32e-2)" "unprognostic (2.70e-1)" "unprognostic (1.79e-1)" "unprognostic (2.37e-3)" "unprognostic (8.02e-2)" "unprognostic (2.31e-2)" "unprognostic (3.27e-1)" "unprognostic (1.18e-1)" "unprognostic (1.02e-1)" "unprognostic (3.66e-2)" "unprognostic (1.52e-2)" "unprognostic (3.83e-1)" "unprognostic (9.19e-2)" "unprognostic (3.76e-1)" VIPR1 "HVR1, RDC1, VPAC1, VPAC1R" ENSG00000114812 "Vasoactive intestinal peptide receptor 1" P32241 3 42489299-42537573 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 124.0" "Cell type enhanced" "Detected in many" "Breast lactating cells: 58.3;Colonocytes: 94.1;Enterocytes: 99.2;Goblet cells: 100.2;Hepatic stellate cells: 64.5;Paneth cells: 50.3;Pericytes: 56.0;Prostatic club cells: 49.4;Prostatic glandular cells: 49.4;Urothelial cells: 59.2" "Cell type enhanced" "Detected in many" "deep-layer near-projecting: 65.5" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 36.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 22 "dendritic cells: 2.1;monocytes: 1.8;T-cells: 2.7" "Cancer enhanced" "Detected in many" "pancreatic cancer: 22.7" "Colon - Colon enterocytes, Prostate - Prostate glandular cells" "Group enriched" "Detected in many" 4 "amygdala: 6.4;basal ganglia: 4.5;cerebral cortex: 9.6;hippocampal formation: 7.7;white matter: 2.5" "Low region specificity" "Detected in all" HPA026777 Approved NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 77: Intestine - Digestion" "Cluster 53: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 118 "HPA026777: " "potential prognostic favorable (1.59e-4)" "unprognostic (1.17e-1)" "unprognostic (9.63e-2)" "unprognostic (1.63e-1)" "unprognostic (2.75e-2)" "unprognostic (7.44e-2)" "unprognostic (4.96e-2)" "unprognostic (2.96e-2)" "unprognostic (8.31e-3)" "validated prognostic favorable (5.29e-5)" "validated prognostic favorable (6.26e-4)" "validated prognostic favorable (9.15e-4)" "validated prognostic favorable (4.31e-4)" "unprognostic (2.48e-3)" "unprognostic (6.44e-2)" "unprognostic (3.23e-1)" "unprognostic (2.10e-1)" "unprognostic (6.45e-2)" "unprognostic (1.16e-1)" "unprognostic (3.49e-2)" "unprognostic (9.96e-2)" "unprognostic (4.28e-1)" "unprognostic (1.64e-1)" "unprognostic (1.53e-2)" "unprognostic (9.37e-2)" "unprognostic (1.10e-1)" "unprognostic (2.07e-2)" "unprognostic (1.38e-1)" VIPR2 "VPAC2, VPAC2R" ENSG00000106018 "Vasoactive intestinal peptide receptor 2" P41587 7 159028175-159144867 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 132.2;Epicardial cells: 125.1;Fibro-adipogenic progenitors: 44.6;Mesothelial cells: 221.8;Müller glia: 105.6;Oligodendrocyte progenitor cells: 82.1;Pancreatic acinar cells: 84.8;Pituicytes/FSCs: 147.6;Rod photoreceptor cells: 63.6;Vascular smooth muscle cells: 57.8" "Cell type enhanced" "Detected in many" "miscellaneous: 55.1;oligodendrocyte precursor cell: 103.2;vascular associated smooth muscle cell: 43.8" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 13.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 17 "plasmacytoid DC: 12.3" "Lineage enriched" "Detected in single" 17 "dendritic cells: 12.3" "Cancer enhanced" "Detected in some" "Leukemia: 5.2;Rhabdoid: 3.6" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Kidney - Fibroblasts, Skeletal muscle - Skeletal myocytes" "Region enhanced" "Detected in many" "olfactory bulb: 27.0" "Low region specificity" "Detected in many" HPA062707 Approved Approved "Focal adhesion sites" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 53: Neurons - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" "Focal adhesion sites" "HPA062707: " "unprognostic (4.15e-2)" "unprognostic (1.31e-2)" "potential prognostic favorable (7.12e-5)" "unprognostic (1.79e-1)" "unprognostic (1.43e-1)" "potential prognostic favorable (4.77e-5)" "unprognostic (1.17e-1)" "unprognostic (6.32e-2)" "unprognostic (1.46e-1)" "unprognostic (9.81e-2)" "unprognostic (1.03e-1)" "unprognostic (1.51e-2)" "unprognostic (5.88e-2)" "unprognostic (1.20e-1)" VIRMA "DKFZP434I116, fSAP121, KIAA1429" ENSG00000164944 "Vir like m6A methyltransferase associated" Q69YN4 8 94487689-94553529 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031530 Approved Supported "Nucleoplasm,Nuclear bodies" No No "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 235 "Nuclear bodies" Nucleoplasm "HPA031530: " "unprognostic (4.61e-2)" "unprognostic (1.08e-2)" "unprognostic (2.62e-2)" "unprognostic (2.45e-1)" "unprognostic (1.10e-1)" "unprognostic (2.32e-1)" "unprognostic (4.74e-3)" "unprognostic (3.92e-1)" "potential prognostic unfavorable (6.74e-5)" "potential prognostic favorable (1.91e-5)" "unprognostic (1.23e-2)" "unprognostic (2.46e-2)" "unprognostic (1.48e-2)" "unprognostic (2.50e-2)" "unprognostic (2.07e-3)" "unprognostic (4.26e-2)" "unprognostic (1.13e-1)" "potential prognostic unfavorable (2.67e-5)" "unprognostic (2.33e-1)" "unprognostic (7.16e-3)" "potential prognostic unfavorable (1.09e-4)" "unprognostic (4.48e-2)" "unprognostic (2.09e-2)" "unprognostic (1.64e-1)" "unprognostic (1.08e-1)" "unprognostic (2.90e-1)" "unprognostic (3.16e-1)" "unprognostic (1.52e-2)" "unprognostic (7.04e-2)" VIT ENSG00000205221 Vitrin Q6UXI7 2 36696690-36814794 "Predicted intracellular proteins, Predicted secreted proteins" Neurogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 33.7;ovary: 35.6;tongue: 38.4" "Cell type enhanced" "Detected in many" "Bergmann glia: 145.3;Fibro-adipogenic progenitors: 351.8;Fibroblasts: 213.4;Goblet cells: 73.0;Leydig cells: 267.5;Migrating cytotrophoblasts: 53.1;Myosatellite cells: 221.6;Peritubular myoid cells: 55.0" "Group enriched" "Detected in some" 30 "Bergmann glia: 142.4;fibroblast: 241.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.3;naive CD8 T-cell: 1.3" "Lineage enriched" "Detected in single" 10 "T-cells: 2.3" "Cancer enriched" "Detected in many" 5 "testis cancer: 57.3" "Lung - Fibroblasts_2, Pituitary gland - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" Other NA NA 38000 "Cluster 24: Non-specific - Transcription" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 15: Non-specific - Transcription" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 108: Fibroblasts - ECM organization" "unprognostic (1.48e-2)" "unprognostic (4.61e-2)" "potential prognostic unfavorable (4.92e-4)" "unprognostic (7.46e-2)" "unprognostic (1.23e-1)" "unprognostic (1.35e-1)" "unprognostic (9.35e-2)" "unprognostic (1.98e-2)" "unprognostic (2.24e-2)" "unprognostic (1.09e-1)" "unprognostic (1.80e-1)" VKORC1 VKCFD2 ENSG00000167397 "Vitamin K epoxide reductase complex subunit 1" Q9BQB6 16 31090842-31095980 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 525.5" "Cell type enhanced" "Detected in some" "Cholangiocytes: 2.0;Enterocytes: 1.9;Gastric chief cells: 4.4;Hepatic stellate cells: 6.5;Hepatocytes: 2.5;pDCs: 2.4;Platelets: 4.2" "Cell type enhanced" "Detected in some" "vascular associated smooth muscle cell: 1.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042720 Approved Supported "Endoplasmic reticulum" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 15 "Endoplasmic reticulum" "HPA042720: " "unprognostic (3.27e-2)" "unprognostic (1.13e-2)" "unprognostic (7.40e-2)" "unprognostic (9.29e-2)" "unprognostic (5.06e-3)" "unprognostic (3.58e-1)" "unprognostic (1.88e-2)" "unprognostic (1.12e-1)" "unprognostic (1.45e-2)" "unprognostic (3.78e-1)" "validated prognostic unfavorable (5.99e-5)" "validated prognostic unfavorable (4.59e-5)" "unprognostic (4.93e-3)" "unprognostic (2.89e-2)" "unprognostic (7.26e-2)" "unprognostic (1.13e-1)" "unprognostic (1.06e-1)" "unprognostic (2.02e-1)" "unprognostic (2.06e-1)" "unprognostic (6.92e-2)" "unprognostic (3.18e-2)" "unprognostic (4.06e-2)" "unprognostic (1.08e-1)" "unprognostic (3.68e-2)" "unprognostic (4.65e-1)" "unprognostic (4.70e-2)" "unprognostic (7.37e-2)" "unprognostic (2.47e-2)" "unprognostic (1.42e-1)" "unprognostic (1.12e-2)" "unprognostic (1.25e-1)" VKORC1L1 ENSG00000196715 "Vitamin K epoxide reductase complex subunit 1 like 1" Q8N0U8 7 65873074-65959563 "Enzymes, FDA approved drug targets, Predicted membrane proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 589.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053954 Approved Supported "Endoplasmic reticulum" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 75: Ovary - Mixed function" "Cluster 14: Neurons - Synaptic function" "Cluster 39: Non-specific - Transcription" "Cluster 89: Adipocytes - Lipid metabolism" 45 "Endoplasmic reticulum" "HPA053954: " "unprognostic (1.66e-1)" "unprognostic (1.05e-1)" "unprognostic (1.11e-2)" "unprognostic (6.19e-3)" "unprognostic (1.26e-1)" "potential prognostic unfavorable (4.01e-4)" "unprognostic (4.49e-3)" "potential prognostic unfavorable (1.34e-4)" "unprognostic (6.27e-2)" "potential prognostic unfavorable (2.81e-7)" "potential prognostic favorable (7.62e-5)" "unprognostic (3.84e-2)" "unprognostic (2.76e-2)" "unprognostic (2.64e-3)" "unprognostic (9.30e-3)" "unprognostic (2.24e-1)" "unprognostic (6.85e-2)" "unprognostic (4.32e-1)" "unprognostic (1.45e-2)" "unprognostic (1.75e-2)" "unprognostic (5.31e-3)" "potential prognostic unfavorable (8.64e-5)" "unprognostic (2.33e-1)" "unprognostic (7.71e-2)" "unprognostic (3.52e-1)" "unprognostic (5.78e-2)" "unprognostic (4.39e-2)" "unprognostic (8.35e-2)" "unprognostic (9.90e-2)" "unprognostic (1.54e-1)" "unprognostic (1.84e-1)" VLDLR "CARMQ1, CHRMQ1, VLDLRCH" ENSG00000147852 "Very low density lipoprotein receptor" P98155 9 2621182-2660056 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol metabolism, Endocytosis, Host-virus interaction, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" Receptor "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 32.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 220.3;Cone photoreceptor cells: 62.1;Epicardial cells: 97.8;Esophageal apical cells: 71.3;Gonadotrophs: 61.6;Myonuclei: 61.0;Pancreatic islet cells: 95.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "eosinophil: 6.3" "Lineage enriched" "Detected in single" 10 "granulocytes: 6.3" "Low cancer specificity" "Detected in many" "Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032462, HPA051312" Uncertain Uncertain "Vesicles,Cytokinetic bridge,Centriolar satellite" Yes NA 320000 "Cluster 61: Non-specific - Transcription" "Cluster 30: White matter - Myelination" "Cluster 15: Kidney cancer - Membrane components" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 7 Vesicles "Cytokinetic bridge, Centriolar satellite" "CAB032462: , HPA051312: " "unprognostic (2.31e-2)" "unprognostic (3.45e-2)" "unprognostic (8.68e-2)" "unprognostic (1.61e-3)" "unprognostic (4.50e-2)" "unprognostic (2.32e-1)" "unprognostic (1.01e-1)" "unprognostic (1.23e-1)" "unprognostic (6.86e-2)" "unprognostic (1.49e-1)" "potential prognostic favorable (3.48e-5)" "unprognostic (1.48e-1)" "unprognostic (6.71e-2)" "unprognostic (3.95e-1)" "unprognostic (1.95e-1)" "unprognostic (2.97e-1)" "unprognostic (8.20e-2)" "unprognostic (3.09e-1)" "unprognostic (1.82e-1)" "unprognostic (8.90e-2)" "unprognostic (3.65e-1)" "unprognostic (1.52e-2)" "unprognostic (4.88e-2)" "unprognostic (3.93e-2)" "unprognostic (2.80e-1)" "unprognostic (3.09e-3)" "unprognostic (1.43e-2)" "unprognostic (1.80e-1)" "potential prognostic unfavorable (2.11e-4)" "unprognostic (7.28e-2)" VMA21 "MEAX, XMEA" ENSG00000160131 "Vacuolar ATPase assembly factor VMA21" Q3ZAQ7 X 151396515-151409364 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 161.2;Kupffer cells: 169.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010972 Uncertain NA NA "Cluster 11: T-cells - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 36: Non-specific - mRNA processing" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 45 "HPA010972: " "unprognostic (9.75e-2)" "unprognostic (1.48e-2)" "unprognostic (6.00e-2)" "unprognostic (7.14e-3)" "unprognostic (1.40e-2)" "unprognostic (1.31e-1)" "unprognostic (2.62e-1)" "unprognostic (1.81e-1)" "unprognostic (4.59e-2)" "unprognostic (3.65e-2)" "unprognostic (2.40e-3)" "unprognostic (1.71e-1)" "unprognostic (5.57e-2)" "validated prognostic unfavorable (3.63e-4)" "validated prognostic unfavorable (5.07e-7)" "unprognostic (6.32e-2)" "unprognostic (4.07e-2)" "unprognostic (2.32e-2)" "unprognostic (1.60e-2)" "unprognostic (3.81e-2)" "unprognostic (1.90e-1)" "unprognostic (3.79e-1)" "unprognostic (6.11e-2)" "unprognostic (1.29e-1)" "unprognostic (3.71e-1)" "unprognostic (3.55e-1)" "unprognostic (2.94e-2)" "unprognostic (1.36e-1)" "unprognostic (3.83e-2)" "unprognostic (3.53e-2)" "unprognostic (2.12e-1)" VMAC ENSG00000187650 "Vimentin type intermediate filament associated coiled-coil protein" Q2NL98 19 5904872-5910853 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Early spermatids: 5.0;Endometrial ciliated cells: 1.6;Gastric chief cells: 5.5;Late primary spermatocytes: 2.0;Late spermatids: 8.0" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 82: Salivary gland - Secretion" "Cluster 6: Non-specific - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 13 "unprognostic (4.92e-3)" "unprognostic (3.03e-1)" "unprognostic (1.45e-1)" "unprognostic (1.94e-1)" "unprognostic (6.07e-2)" "unprognostic (1.02e-1)" "unprognostic (2.76e-1)" "unprognostic (1.24e-1)" "potential prognostic favorable (5.11e-4)" "unprognostic (3.24e-2)" "potential prognostic unfavorable (9.88e-4)" "unprognostic (2.63e-1)" "unprognostic (1.14e-1)" "unprognostic (4.66e-1)" "unprognostic (1.04e-1)" "unprognostic (2.00e-2)" "unprognostic (8.82e-2)" "unprognostic (7.27e-2)" "unprognostic (1.79e-1)" "unprognostic (6.59e-2)" "unprognostic (2.62e-2)" "unprognostic (8.21e-2)" "unprognostic (3.62e-1)" "unprognostic (4.36e-2)" "unprognostic (5.01e-2)" "unprognostic (4.38e-3)" "unprognostic (2.58e-2)" "unprognostic (9.87e-2)" "unprognostic (2.44e-1)" "unprognostic (2.25e-1)" "unprognostic (1.39e-3)" VMO1 ENSG00000182853 "Vitelline membrane outer layer 1 homolog" Q7Z5L0 17 4785285-4786433 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 22.8;pituitary gland: 29.2" "Cell type enriched" "Detected in many" 8 "Conjunctival goblet cells: 6465.0" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 6.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "non-classical monocyte: 112.2" "Lineage enriched" "Detected in many" 9 "monocytes: 112.2" "Cancer enhanced" "Detected in many" "Bone cancer: 4.9" "Spleen - Macrophages, Stomach - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA023038 Uncertain "Secreted to blood" "No annotated function" NA NA 1900000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 38: Secretory epithelial cells - Exocrine secretion" "HPA023038: " "unprognostic (4.16e-2)" "unprognostic (1.38e-1)" "unprognostic (2.66e-2)" "unprognostic (1.55e-2)" "unprognostic (4.30e-2)" "unprognostic (4.03e-2)" "unprognostic (3.82e-2)" "unprognostic (2.52e-1)" "unprognostic (1.18e-1)" "unprognostic (6.35e-2)" "potential prognostic unfavorable (3.62e-8)" "unprognostic (1.40e-1)" "unprognostic (2.24e-2)" "unprognostic (4.22e-2)" "unprognostic (3.11e-2)" "unprognostic (2.92e-2)" "unprognostic (7.83e-2)" "unprognostic (1.54e-2)" "unprognostic (1.10e-1)" "unprognostic (1.48e-1)" "unprognostic (1.79e-1)" "unprognostic (6.20e-2)" "unprognostic (9.31e-2)" "unprognostic (2.15e-1)" "unprognostic (9.25e-2)" "unprognostic (3.72e-2)" "unprognostic (1.78e-1)" "unprognostic (3.85e-3)" "unprognostic (5.55e-2)" "unprognostic (4.28e-1)" "unprognostic (1.81e-1)" VMP1 "EPG3, TANGO5, TMEM49" ENSG00000062716 "Vacuole membrane protein 1" Q96GC9 17 59707192-59842255 "Essential proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Autophagy, Cell adhesion, Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Neutrophils: 5581.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "neutrophil: 3016.5" "Lineage enriched" "Detected in all" 5 "granulocytes: 3016.5" "Low cancer specificity" "Detected in all" "Liver - Neutrophils, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030773, HPA064780" Approved Approved "Nucleoli,Endoplasmic reticulum" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 28: Liver & Adrenal gland - Secretion" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" 23 "Endoplasmic reticulum" Nucleoli "HPA030773: , HPA064780: " "unprognostic (1.30e-1)" "unprognostic (1.01e-1)" "unprognostic (4.58e-2)" "unprognostic (1.02e-2)" "unprognostic (4.42e-2)" "unprognostic (9.17e-3)" "unprognostic (2.04e-1)" "unprognostic (2.87e-2)" "potential prognostic unfavorable (8.08e-7)" "unprognostic (2.26e-2)" "unprognostic (1.18e-1)" "unprognostic (1.96e-2)" "potential prognostic unfavorable (9.66e-4)" "unprognostic (5.47e-3)" "unprognostic (1.24e-1)" "unprognostic (1.41e-2)" "unprognostic (2.55e-1)" "unprognostic (2.13e-1)" "unprognostic (2.05e-2)" "unprognostic (1.60e-1)" "unprognostic (1.54e-1)" "potential prognostic unfavorable (5.43e-5)" "unprognostic (1.76e-1)" "unprognostic (4.22e-2)" "unprognostic (5.01e-3)" "unprognostic (2.47e-1)" "unprognostic (8.65e-2)" "unprognostic (1.07e-1)" "unprognostic (2.39e-2)" "unprognostic (4.91e-2)" VN1R1 "V1RL1, VNR19I1, ZVNH1, ZVNR1" ENSG00000178201 "Vomeronasal 1 receptor 1" Q9GZP7 19 57454790-57457140 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Pheromone response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 6.6;retina: 7.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Heart muscle - Cardiomyocytes" "Not detected" "Not detected" HPA062209 Uncertain Nucleoplasm,Vesicles NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" Vesicles Nucleoplasm "HPA062209: " "unprognostic (2.93e-1)" "unprognostic (9.62e-2)" "unprognostic (1.69e-1)" "unprognostic (5.23e-1)" "unprognostic (7.36e-2)" "unprognostic (2.05e-1)" "unprognostic (9.87e-2)" "unprognostic (6.87e-3)" "unprognostic (5.26e-3)" VN1R2 V1RL2 ENSG00000196131 "Vomeronasal 1 receptor 2" Q8NFZ6 19 53258292-53261837 "G-protein coupled receptors, Predicted membrane proteins" "Pheromone response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 28 "Early spermatids: 23.3;Late spermatids: 11.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA044551 Uncertain NA NA "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 56: Non-specific - Sensory perception" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" "HPA044551: " "unprognostic (2.80e-2)" "unprognostic (2.05e-2)" VN1R4 V1RL4 ENSG00000228567 "Vomeronasal 1 receptor 4" Q7Z5H5 19 53266676-53267723 "G-protein coupled receptors, Predicted membrane proteins" "Pheromone response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA027018 Uncertain NA NA "Cluster 10: Ciliated cells - Ion channel activity" "HPA027018: " VN1R5 V1RL5 ENSG00000197617 "Vomeronasal 1 receptor 5 (gene/pseudogene)" 1 247255972-247257210 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" VNN1 Tiff66 ENSG00000112299 "Vanin 1" O95497 6 132680849-132714055 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "gallbladder: 83.9;intestine: 128.3;liver: 204.4" "Group enriched" "Detected in many" 5 "Neutrophil progenitors: 477.7;Neutrophils: 1036.7" "Group enriched" "Detected in some" 10 "central nervous system macrophage: 5.0;leukocyte: 16.8" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 40.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 13.7;non-classical monocyte: 12.0" "Group enriched" "Detected in many" 80 "dendritic cells: 5.0;granulocytes: 8.5;monocytes: 13.7" "Cancer enhanced" "Detected in many" "liver cancer: 13.2;thyroid cancer: 9.6" "Adipose subcutaneous - Macrophages, Adrenal gland - Macrophages, Colon - Macrophages, Kidney - Proximal tubular cells, Lung - Neutrophils_2, Minor Salivary Gland - Minor salivary glandular cells, Spleen - Neutrophils_2" "Region enhanced" "Detected in single" "white matter: 2.4" "Not detected" "Not detected" "HPA046103, HPA064145" Approved Approved Vesicles "Intracellular and membrane" Enzyme NA NA 180000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 6: Non-specific - Immune response" "Cluster 7: Liver cancer - Metabolism" "Cluster 48: Neutrophils - Phagocytosis & degranulation" Vesicles "HPA046103: , HPA064145: " "unprognostic (2.67e-2)" "unprognostic (1.44e-1)" "unprognostic (8.17e-3)" "unprognostic (1.02e-2)" "unprognostic (1.65e-2)" "unprognostic (1.49e-2)" "unprognostic (6.86e-3)" "unprognostic (5.59e-2)" "unprognostic (1.72e-2)" "unprognostic (2.30e-2)" "unprognostic (1.56e-1)" "unprognostic (1.35e-1)" "potential prognostic unfavorable (7.45e-4)" "unprognostic (1.37e-1)" "unprognostic (5.43e-2)" "unprognostic (1.04e-1)" "unprognostic (2.60e-3)" "unprognostic (5.83e-2)" "unprognostic (1.14e-2)" "unprognostic (1.71e-2)" "unprognostic (2.98e-1)" "unprognostic (3.42e-1)" "unprognostic (3.48e-2)" "unprognostic (5.36e-2)" "potential prognostic unfavorable (5.64e-4)" VNN2 "FOAP-4, GPI-80" ENSG00000112303 "Vanin 2" O95498 6 132743870-132763459 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 29.8;lymphoid tissue: 66.0" "Cell type enriched" "Detected in many" 25 "Neutrophils: 2013.2" "Group enriched" "Detected in some" 7 "central nervous system macrophage: 7.1;fibroblast: 11.2;leukocyte: 19.4;pericyte: 9.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 7 "neutrophil: 479.1" "Lineage enriched" "Detected in all" 7 "granulocytes: 479.1" "Cancer enriched" "Detected in many" 7 "lymphoma: 32.9" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophils_2, Skeletal muscle - Neutrophils, Spleen - Neutrophils_2, Thyroid gland - Neutrophils" "Low region specificity" "Detected in some" NA NA 75000 "Cluster 4: Neutrophils - Degranulation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 3 "unprognostic (4.19e-2)" "unprognostic (1.85e-1)" "unprognostic (2.69e-2)" "unprognostic (1.11e-2)" "unprognostic (4.57e-2)" "unprognostic (3.68e-2)" "unprognostic (1.62e-2)" "unprognostic (2.05e-1)" "unprognostic (1.50e-3)" "unprognostic (3.30e-2)" "unprognostic (5.81e-2)" "unprognostic (2.63e-2)" "potential prognostic unfavorable (5.04e-5)" "unprognostic (2.19e-2)" "unprognostic (7.44e-2)" "unprognostic (5.87e-2)" "unprognostic (1.88e-1)" "unprognostic (1.24e-1)" "unprognostic (1.70e-1)" "unprognostic (3.89e-1)" "unprognostic (1.35e-1)" "unprognostic (5.06e-2)" "unprognostic (1.86e-1)" "unprognostic (4.10e-2)" "unprognostic (2.20e-1)" "unprognostic (1.59e-1)" "unprognostic (9.50e-3)" "unprognostic (4.96e-1)" VOPP1 "DKFZp564K0822, ECop, FLJ20532, GASP, WBP1L2" ENSG00000154978 "VOPP1 WW domain binding protein" Q96AW1 7 55436056-55572988 "Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 233.4" "Cell type enhanced" "Detected in many" "cDC: 410.2;Cone photoreceptor cells: 1262.8;Kupffer cells: 371.0;Neutrophils: 397.9;Plasma cells: 728.9;Rod photoreceptor cells: 841.0;Thyrotrophs: 388.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 327.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 82: Dendritic cells - Antigen presentation" 3 "unprognostic (1.71e-2)" "unprognostic (2.80e-1)" "unprognostic (1.10e-2)" "unprognostic (1.70e-1)" "unprognostic (2.14e-2)" "unprognostic (2.21e-2)" "unprognostic (7.39e-2)" "unprognostic (9.53e-3)" "unprognostic (9.80e-3)" "unprognostic (7.36e-2)" "unprognostic (1.43e-1)" "unprognostic (5.63e-2)" "unprognostic (9.44e-2)" "validated prognostic unfavorable (1.39e-5)" "validated prognostic unfavorable (5.72e-5)" "unprognostic (2.49e-2)" "unprognostic (4.27e-2)" "unprognostic (1.33e-1)" "unprognostic (6.68e-2)" "unprognostic (1.59e-1)" "unprognostic (2.11e-2)" "unprognostic (8.97e-3)" "unprognostic (3.48e-2)" "unprognostic (4.26e-2)" "unprognostic (4.12e-2)" "unprognostic (8.82e-2)" "unprognostic (4.32e-1)" "unprognostic (5.81e-2)" "unprognostic (3.53e-2)" "unprognostic (6.45e-2)" "unprognostic (2.06e-1)" VPREB1 "CD179A, VpreB" ENSG00000169575 "V-set pre-B cell surrogate light chain 1" P12018 22 22244780-22245515 "CD markers, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 22 "bone marrow: 28.1" "Cell type enriched" "Detected in some" 50 "Thymocytes: 61.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "memory B-cell: 5.7;naive B-cell: 5.3" "Lineage enriched" "Detected in many" 5 "B-cells: 5.7" "Cancer enriched" "Detected in some" 4 "Leukemia: 204.5" "Breast - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA055886 Approved "Intracellular and membrane" "No annotated function" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 35: RS4;11 - Unknown function" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" "HPA055886: " VPREB3 8HS20 ENSG00000128218 "V-set pre-B cell surrogate light chain 3" Q9UKI3 22 23752743-23754425 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 48.5;intestine: 74.4;lymphoid tissue: 110.8" "Group enriched" "Detected in some" 4 "B-cells: 198.9;Epididymal principal cells: 86.8" "Cell type enhanced" "Detected in some" "leukocyte: 1.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 707 "memory B-cell: 756.8;naive B-cell: 807.5" "Lineage enriched" "Detected in many" 730 "B-cells: 807.5" "Group enriched" "Detected in some" 34 "Leukemia: 127.1;lymphoma: 273.1" "Pituitary gland - Gonadotropes, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA003041 Supported "Intracellular and membrane" "No annotated function" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 18: Non-specific - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 87: B-cells - Adaptive immunity: Humoral response" "HPA003041: " "unprognostic (1.63e-1)" "unprognostic (1.18e-2)" "unprognostic (1.21e-3)" "unprognostic (1.66e-2)" "unprognostic (1.19e-1)" "unprognostic (1.63e-1)" "unprognostic (3.21e-2)" "unprognostic (4.78e-2)" "unprognostic (5.93e-2)" "unprognostic (1.72e-2)" "unprognostic (4.18e-2)" "unprognostic (1.39e-3)" "unprognostic (2.54e-1)" "unprognostic (1.33e-1)" "unprognostic (2.02e-2)" "unprognostic (9.83e-2)" "unprognostic (3.21e-2)" "unprognostic (1.72e-2)" "unprognostic (6.68e-2)" "unprognostic (5.99e-3)" "unprognostic (2.67e-1)" "unprognostic (4.98e-2)" "unprognostic (6.57e-2)" "unprognostic (4.08e-2)" "unprognostic (6.82e-3)" "unprognostic (3.76e-2)" "unprognostic (5.62e-2)" "unprognostic (1.80e-1)" "unprognostic (1.00e-1)" VPS11 "PEP5, RNF108" ENSG00000160695 "VPS11 core subunit of CORVET and HOPS complexes" 11 119067818-119081972 "Human disease related genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 11.3;Bergmann glia: 9.4;Brain excitatory neurons: 13.6;Brain inhibitory neurons: 13.5;Choroid plexus epithelial cells: 7.6;Distal convoluted tubule cells: 8.8;Ependymal cells: 7.8;Loop of henle epithelial cells: 8.6;Microglia: 12.0;Oligodendrocyte progenitor cells: 11.6;Oligodendrocytes: 16.2;Other brain neurons: 13.2;Podocytes: 8.3;Proximal tubule cells: 8.5;Renal collecting duct intercalated cells: 12.1;Renal collecting duct principal cells: 9.0;Renal connecting tubule cells: 7.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039020 Approved Approved Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 64: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 24: Non-specific - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" 12 Cytosol "HPA039020: " "unprognostic (1.47e-1)" "unprognostic (2.37e-1)" "unprognostic (4.16e-3)" "unprognostic (2.85e-1)" "unprognostic (2.65e-1)" "unprognostic (3.94e-3)" "unprognostic (1.01e-1)" "unprognostic (1.13e-2)" "unprognostic (2.72e-2)" "unprognostic (1.76e-3)" "validated prognostic favorable (9.77e-9)" "validated prognostic favorable (3.04e-4)" "unprognostic (1.12e-2)" "unprognostic (1.10e-3)" "unprognostic (3.52e-1)" "unprognostic (2.11e-1)" "unprognostic (3.52e-3)" "unprognostic (5.25e-2)" "unprognostic (1.14e-2)" "unprognostic (2.16e-1)" "unprognostic (4.29e-2)" "unprognostic (1.19e-1)" "unprognostic (2.73e-2)" "unprognostic (1.67e-1)" "unprognostic (2.27e-1)" "unprognostic (1.37e-1)" "unprognostic (1.86e-1)" "unprognostic (5.64e-2)" "unprognostic (2.28e-1)" "unprognostic (2.45e-1)" "unprognostic (6.64e-2)" VPS13A "BLTP5A, CHAC, KIAA0986" ENSG00000197969 "Vacuolar protein sorting 13 homolog A" Q96RL7 9 77177445-77421537 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Lipid transport, Transport" "Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Myonuclei: 608.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021652, HPA021662" Supported Supported Mitochondria NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 18 Mitochondria "HPA021652: , HPA021662: " "unprognostic (2.21e-2)" "unprognostic (2.57e-1)" "unprognostic (1.41e-2)" "unprognostic (2.03e-2)" "unprognostic (2.34e-1)" "unprognostic (3.04e-1)" "unprognostic (4.50e-2)" "unprognostic (9.11e-2)" "unprognostic (7.27e-2)" "unprognostic (5.72e-2)" "potential prognostic favorable (6.84e-6)" "unprognostic (9.21e-3)" "unprognostic (8.53e-2)" "unprognostic (8.69e-3)" "unprognostic (7.55e-2)" "unprognostic (5.50e-2)" "unprognostic (3.72e-2)" "unprognostic (8.95e-2)" "unprognostic (1.94e-2)" "unprognostic (7.84e-3)" "unprognostic (4.98e-2)" "unprognostic (1.45e-1)" "unprognostic (2.00e-1)" "unprognostic (1.06e-1)" "unprognostic (8.95e-3)" "unprognostic (4.88e-1)" "unprognostic (1.36e-1)" "unprognostic (3.60e-1)" "unprognostic (2.91e-1)" "unprognostic (1.38e-1)" "unprognostic (2.38e-1)" VPS13B "BLTP5B, CHS1, COH1" ENSG00000132549 "Vacuolar protein sorting 13 homolog B" Q7Z7G8 8 99013266-99877580 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Disease variant, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 1252.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043865 Approved "Cell Junctions" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 108: Fibroblasts - ECM organization" 3 "Cell Junctions" "HPA043865: " "unprognostic (5.95e-2)" "unprognostic (2.33e-2)" "unprognostic (5.24e-3)" "unprognostic (2.60e-2)" "unprognostic (5.47e-1)" "unprognostic (1.48e-1)" "unprognostic (2.72e-2)" "unprognostic (1.48e-1)" "unprognostic (7.57e-2)" "potential prognostic unfavorable (1.33e-4)" "potential prognostic favorable (4.70e-6)" "unprognostic (1.22e-3)" "unprognostic (1.28e-1)" "unprognostic (2.66e-1)" "unprognostic (2.81e-1)" "unprognostic (1.36e-1)" "unprognostic (2.51e-2)" "unprognostic (1.89e-1)" "unprognostic (6.91e-2)" "potential prognostic unfavorable (5.86e-4)" "unprognostic (7.48e-2)" "unprognostic (7.52e-3)" "potential prognostic unfavorable (2.20e-4)" "unprognostic (1.61e-1)" "unprognostic (8.46e-2)" "unprognostic (3.32e-3)" "unprognostic (2.87e-1)" "unprognostic (8.98e-2)" "unprognostic (1.49e-1)" "unprognostic (1.87e-3)" "unprognostic (8.59e-2)" VPS13C "BLTP5C, FLJ10381, FLJ20136, KIAA1421" ENSG00000129003 "Vacuolar protein sorting 13 homolog C" Q709C8 15 61852389-62060473 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Lipid transport, Transport" "Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043507 Uncertain NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 30: White matter - Myelination" "Cluster 58: Non-specific - Nuclear processes" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 26 "HPA043507: " "unprognostic (8.92e-2)" "unprognostic (1.53e-2)" "unprognostic (3.75e-1)" "unprognostic (5.89e-2)" "unprognostic (2.61e-1)" "unprognostic (8.78e-2)" "unprognostic (1.98e-2)" "unprognostic (1.07e-1)" "unprognostic (1.83e-1)" "unprognostic (4.03e-3)" "potential prognostic favorable (1.72e-6)" "unprognostic (1.92e-3)" "unprognostic (1.99e-1)" "unprognostic (2.48e-1)" "unprognostic (1.98e-1)" "unprognostic (6.95e-3)" "unprognostic (1.08e-1)" "unprognostic (3.10e-2)" "unprognostic (1.26e-1)" "unprognostic (5.59e-3)" "unprognostic (4.13e-1)" "unprognostic (1.51e-1)" "unprognostic (1.40e-1)" "unprognostic (7.90e-2)" "unprognostic (3.93e-3)" "unprognostic (1.37e-2)" "unprognostic (3.39e-1)" "unprognostic (1.14e-1)" "unprognostic (1.29e-1)" "unprognostic (4.43e-2)" "unprognostic (9.50e-2)" VPS13D "BLTP5D, FLJ10619, KIAA0453" ENSG00000048707 "Vacuolar protein sorting 13 homolog D" Q5THJ4 1 12230030-12512047 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Lipid transport, Transport" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Endothelial cells, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027332, HPA051621" Uncertain Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 24: Non-specific - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 37: Non-specific - mRNA processing" "Cluster 110: Mural cells - ECM organization" 7 "Nucleoplasm, Vesicles" Cytosol "HPA027332: , HPA051621: " "unprognostic (5.03e-2)" "unprognostic (6.52e-3)" "unprognostic (2.78e-1)" "unprognostic (1.85e-1)" "unprognostic (6.43e-2)" "unprognostic (7.79e-2)" "unprognostic (1.99e-1)" "unprognostic (7.86e-2)" "unprognostic (1.52e-2)" "unprognostic (7.27e-2)" "unprognostic (1.18e-3)" "unprognostic (1.01e-3)" "potential prognostic favorable (3.09e-5)" "unprognostic (2.70e-1)" "unprognostic (1.51e-1)" "unprognostic (1.05e-3)" "unprognostic (1.98e-1)" "unprognostic (1.30e-1)" "unprognostic (1.25e-1)" "potential prognostic unfavorable (4.99e-4)" "unprognostic (3.69e-2)" "unprognostic (9.50e-2)" "unprognostic (2.04e-1)" "unprognostic (9.23e-2)" "unprognostic (5.33e-3)" "unprognostic (1.22e-2)" "unprognostic (6.57e-2)" "unprognostic (2.02e-1)" "unprognostic (4.76e-3)" "unprognostic (1.37e-3)" "unprognostic (2.37e-1)" VPS16 ENSG00000215305 "VPS16 core subunit of CORVET and HOPS complexes" Q9H269 20 2840703-2866732 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Autophagy, Protein transport, Transport" "Disease variant, Dystonia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043229, HPA048661" Approved NA NA 5500 "Cluster 25: Non-specific - Unknown function" "Cluster 49: Non-specific - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 26 "HPA043229: , HPA048661: " "unprognostic (8.16e-2)" "unprognostic (8.02e-2)" "unprognostic (1.04e-2)" "unprognostic (1.68e-1)" "unprognostic (4.74e-2)" "unprognostic (9.68e-2)" "unprognostic (3.14e-1)" "unprognostic (2.73e-2)" "unprognostic (1.65e-2)" "unprognostic (2.21e-2)" "unprognostic (5.92e-3)" "unprognostic (3.45e-1)" "unprognostic (2.94e-1)" "unprognostic (7.57e-3)" "unprognostic (1.06e-2)" "unprognostic (1.58e-1)" "unprognostic (2.90e-2)" "unprognostic (3.00e-2)" "unprognostic (1.90e-1)" "unprognostic (1.90e-2)" "unprognostic (6.00e-2)" "unprognostic (7.00e-2)" "unprognostic (1.15e-1)" "unprognostic (2.13e-1)" "unprognostic (3.85e-1)" "unprognostic (3.89e-2)" "unprognostic (3.00e-1)" "unprognostic (2.24e-1)" "unprognostic (2.68e-1)" "unprognostic (3.80e-2)" "unprognostic (1.63e-1)" VPS18 "KIAA1475, PEP3" ENSG00000104142 "VPS18 core subunit of CORVET and HOPS complexes" Q9P253 15 40894450-40903975 "Essential proteins, Predicted intracellular proteins" "Autophagy, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 39.9;Neutrophils: 79.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040701 Approved NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 52: Non-specific - Cellular respiration" "Cluster 45: Non-specific - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 39 "HPA040701: " "unprognostic (1.44e-1)" "unprognostic (1.29e-1)" "unprognostic (2.78e-2)" "potential prognostic unfavorable (7.99e-4)" "unprognostic (2.00e-1)" "unprognostic (6.48e-2)" "unprognostic (1.38e-1)" "unprognostic (9.55e-2)" "unprognostic (9.17e-2)" "unprognostic (2.47e-1)" "potential prognostic favorable (2.20e-4)" "unprognostic (6.92e-3)" "potential prognostic favorable (9.00e-4)" "unprognostic (5.26e-3)" "unprognostic (1.07e-2)" "unprognostic (2.24e-2)" "unprognostic (2.01e-2)" "unprognostic (1.41e-1)" "unprognostic (1.62e-1)" "unprognostic (5.35e-2)" "unprognostic (1.51e-1)" "unprognostic (2.97e-2)" "unprognostic (3.67e-1)" "unprognostic (2.63e-1)" "unprognostic (4.98e-2)" "unprognostic (2.18e-1)" "unprognostic (1.57e-1)" "unprognostic (2.79e-1)" "unprognostic (3.69e-1)" "unprognostic (1.06e-1)" "unprognostic (2.33e-2)" VPS25 "DERP9, EAP20, MGC10540" ENSG00000131475 "Vacuolar protein sorting 25 homolog" Q9BRG1 17 42773449-42779599 "Essential proteins, Predicted intracellular proteins" "Protein transport, Transcription, Transcription regulation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 154.8;Esophageal apical cells: 277.2;Esophageal suprabasal cells: 289.0;Extravillous trophoblasts: 240.0;Migrating cytotrophoblasts: 162.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Colon - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004978, HPA021992, HPA052217, HPA057284" Uncertain Supported Vesicles NA Yes "Cluster 29: Non-specific - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 15: Kidney cancer - Membrane components" "Cluster 85: Squamous epithelial cells - Keratinization" 39 Vesicles "CAB004978: , HPA021992: , HPA052217: , HPA057284: " "unprognostic (3.32e-2)" "unprognostic (1.73e-2)" "unprognostic (2.12e-1)" "unprognostic (9.62e-2)" "unprognostic (9.76e-2)" "unprognostic (1.35e-1)" "unprognostic (2.44e-1)" "unprognostic (2.30e-1)" "potential prognostic unfavorable (2.20e-4)" "unprognostic (2.81e-2)" "unprognostic (3.42e-3)" "unprognostic (2.26e-1)" "unprognostic (1.23e-3)" "unprognostic (1.03e-3)" "potential prognostic unfavorable (5.72e-7)" "potential prognostic unfavorable (2.71e-4)" "unprognostic (1.70e-1)" "unprognostic (5.79e-3)" "unprognostic (2.10e-2)" "unprognostic (1.06e-1)" "unprognostic (9.41e-3)" "unprognostic (2.97e-2)" "unprognostic (1.30e-1)" "unprognostic (1.45e-1)" "unprognostic (3.49e-3)" "unprognostic (3.56e-1)" "unprognostic (5.19e-2)" "unprognostic (2.36e-1)" "unprognostic (3.52e-1)" "unprognostic (1.85e-1)" "unprognostic (7.08e-2)" VPS26A "Hbeta58, PEP8A, VPS26" ENSG00000122958 "VPS26 retromer complex component A" O75436 10 69123512-69174412 "Plasma proteins, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 298.0;Syncytiotrophoblasts: 331.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011602, HPA057498, CAB075733" Supported Enhanced Endosomes,Lysosomes NA NA 65000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 44 "Endosomes, Lysosomes" "CAB011602: , CAB075733: , HPA057498: " "unprognostic (1.20e-1)" "unprognostic (5.12e-3)" "unprognostic (3.32e-3)" "unprognostic (2.94e-1)" "unprognostic (1.11e-1)" "unprognostic (3.36e-2)" "unprognostic (2.17e-1)" "unprognostic (4.33e-3)" "potential prognostic unfavorable (8.45e-4)" "unprognostic (1.40e-1)" "potential prognostic favorable (2.63e-7)" "unprognostic (6.96e-2)" "unprognostic (2.71e-1)" "potential prognostic unfavorable (3.97e-6)" "unprognostic (1.15e-3)" "unprognostic (4.67e-2)" "unprognostic (1.13e-1)" "unprognostic (2.38e-1)" "unprognostic (5.76e-3)" "unprognostic (1.03e-1)" "unprognostic (1.19e-3)" "potential prognostic unfavorable (5.34e-4)" "unprognostic (3.57e-3)" "unprognostic (1.06e-1)" "unprognostic (1.18e-1)" "unprognostic (3.74e-1)" "unprognostic (2.04e-1)" "unprognostic (1.40e-1)" "unprognostic (2.57e-1)" "unprognostic (1.02e-1)" "unprognostic (9.28e-3)" VPS26B "MGC10485, Pep8b" ENSG00000151502 "VPS26 retromer complex component B" Q4G0F5 11 134224671-134247788 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 109.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038172 Uncertain NA NA 20000 "Cluster 45: Eosinophils - Unknown function" "Cluster 2: Non-specific - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 18 "HPA038172: " "unprognostic (3.62e-3)" "unprognostic (2.95e-2)" "unprognostic (1.56e-2)" "unprognostic (1.20e-1)" "unprognostic (2.14e-1)" "unprognostic (2.16e-1)" "unprognostic (1.98e-1)" "unprognostic (8.50e-3)" "unprognostic (3.23e-2)" "unprognostic (2.20e-3)" "potential prognostic favorable (3.45e-4)" "unprognostic (1.60e-1)" "unprognostic (2.51e-2)" "unprognostic (5.73e-2)" "unprognostic (1.64e-1)" "unprognostic (1.79e-1)" "unprognostic (3.57e-3)" "unprognostic (3.94e-1)" "unprognostic (5.71e-2)" "unprognostic (4.51e-2)" "unprognostic (1.12e-2)" "unprognostic (6.04e-2)" "unprognostic (9.80e-2)" "unprognostic (3.60e-1)" "unprognostic (4.71e-2)" "unprognostic (1.10e-1)" "unprognostic (9.12e-2)" "unprognostic (1.64e-2)" "unprognostic (1.73e-1)" "unprognostic (3.02e-1)" "potential prognostic favorable (3.04e-4)" VPS26C "DCRA, DSCR3" ENSG00000157538 "VPS26 endosomal protein sorting factor C" O14972 21 37223420-37267919 "Plasma proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023288 Supported Approved Mitochondria NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 76: Non-specific - Metabolism" "Cluster 27: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 50 Mitochondria "HPA023288: " "unprognostic (2.24e-3)" "potential prognostic unfavorable (3.75e-4)" "unprognostic (1.25e-2)" "unprognostic (1.32e-1)" "unprognostic (2.59e-1)" "unprognostic (3.18e-1)" "unprognostic (3.37e-1)" "unprognostic (5.12e-2)" "unprognostic (4.69e-3)" "potential prognostic favorable (2.04e-9)" "unprognostic (3.59e-2)" "unprognostic (3.03e-2)" "unprognostic (2.57e-2)" "unprognostic (1.52e-1)" "unprognostic (8.50e-2)" "unprognostic (2.65e-2)" "unprognostic (2.69e-1)" "unprognostic (5.53e-2)" "unprognostic (5.68e-2)" "unprognostic (2.78e-2)" "unprognostic (2.62e-1)" "unprognostic (1.97e-1)" "unprognostic (4.58e-2)" "unprognostic (4.07e-2)" "unprognostic (4.45e-1)" "unprognostic (1.44e-1)" "unprognostic (2.54e-1)" "unprognostic (1.77e-2)" "unprognostic (1.12e-1)" VPS28 ENSG00000160948 "VPS28 subunit of ESCRT-I" Q9UK41 8 144423601-144428563 "Essential proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Enterocytes: 253.5;Late primary spermatocytes: 296.5;Platelets: 274.9" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 22.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "breast cancer: 13.8" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024688, HPA024745" Supported Supported Vesicles,Cytosol NA NA 4800 "Cluster 22: Eosinophils - Transcription" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 49 Vesicles Cytosol "HPA024688: , HPA024745: " "unprognostic (4.17e-1)" "unprognostic (4.07e-1)" "unprognostic (9.42e-2)" "unprognostic (6.36e-2)" "unprognostic (3.30e-1)" "unprognostic (1.18e-1)" "unprognostic (2.80e-2)" "unprognostic (6.13e-2)" "unprognostic (2.04e-1)" "unprognostic (2.20e-1)" "unprognostic (7.09e-2)" "unprognostic (2.82e-1)" "unprognostic (8.96e-2)" "unprognostic (1.24e-1)" "unprognostic (6.20e-3)" "unprognostic (1.35e-1)" "unprognostic (3.81e-1)" "unprognostic (2.13e-1)" "unprognostic (2.25e-1)" "unprognostic (3.37e-1)" VPS29 "DC15, DC7, PEP11" ENSG00000111237 "VPS29 retromer complex component" Q9UBQ0 12 110491083-110502111 "Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 630.5;Gastric progenitor cells: 610.1;Hofbauer cells: 543.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039748 Uncertain Supported Vesicles,Cytosol NA NA 200000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 97: Non-specific - Cellular respiration" 102 "Vesicles, Cytosol" "HPA039748: " "unprognostic (4.31e-1)" "unprognostic (2.14e-2)" "unprognostic (4.47e-2)" "potential prognostic favorable (9.54e-4)" "unprognostic (6.91e-2)" "unprognostic (6.11e-2)" "unprognostic (1.19e-1)" "unprognostic (1.54e-1)" "unprognostic (1.73e-2)" "unprognostic (2.24e-2)" "potential prognostic favorable (4.87e-4)" "unprognostic (8.22e-2)" "unprognostic (1.49e-1)" "validated prognostic unfavorable (6.56e-7)" "validated prognostic unfavorable (6.42e-4)" "unprognostic (8.38e-2)" "unprognostic (2.75e-1)" "unprognostic (6.54e-2)" "unprognostic (1.61e-1)" "potential prognostic favorable (3.94e-4)" "unprognostic (8.36e-3)" "unprognostic (1.69e-1)" "unprognostic (5.25e-2)" "unprognostic (1.77e-2)" "unprognostic (5.09e-2)" "unprognostic (3.19e-1)" "unprognostic (1.64e-2)" "unprognostic (5.32e-2)" "unprognostic (2.78e-1)" "unprognostic (3.77e-1)" "unprognostic (2.10e-1)" VPS33A ENSG00000139719 "VPS33A core subunit of CORVET and HOPS complexes" Q96AX1 12 122229564-122266494 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Autophagy, Protein transport, Transport" "Disease variant, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 7 "Astrocytes: 15.3;Bergmann glia: 15.8;Brain excitatory neurons: 20.5;Brain inhibitory neurons: 19.6;Choroid plexus epithelial cells: 31.5;Ependymal cells: 15.3;Microglia: 27.9;Oligodendrocyte progenitor cells: 18.1;Oligodendrocytes: 24.0;Other brain neurons: 20.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Macrophages, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038701 Approved Nucleoplasm NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 34: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 22: Non-specific - Basic cellular functions" 48 Nucleoplasm "HPA038701: " "unprognostic (4.31e-2)" "unprognostic (6.05e-3)" "unprognostic (1.16e-1)" "unprognostic (6.09e-3)" "unprognostic (2.37e-1)" "unprognostic (9.66e-2)" "unprognostic (3.49e-1)" "unprognostic (3.36e-2)" "unprognostic (2.39e-1)" "potential prognostic unfavorable (1.74e-6)" "unprognostic (7.51e-2)" "unprognostic (3.94e-1)" "unprognostic (9.02e-2)" "potential prognostic unfavorable (6.36e-4)" "unprognostic (3.53e-2)" "unprognostic (7.17e-2)" "unprognostic (1.69e-1)" "unprognostic (2.68e-2)" "unprognostic (3.33e-1)" "unprognostic (2.51e-1)" "potential prognostic unfavorable (6.10e-4)" "unprognostic (3.35e-2)" "unprognostic (1.19e-2)" "unprognostic (3.25e-2)" "unprognostic (5.85e-3)" "unprognostic (2.02e-1)" "unprognostic (1.44e-1)" "unprognostic (2.20e-1)" "unprognostic (4.87e-1)" "unprognostic (7.84e-2)" "unprognostic (2.65e-1)" VPS33B FLJ14848 ENSG00000184056 "VPS33B late endosome and lysosome associated" Q9H267 15 90998673-91022603 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Deafness, Disease variant, Ichthyosis, Intrahepatic cholestasis, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Early primary spermatocytes: 2.7;Oocytes: 4.6;Parietal cells: 7.1;Sertoli cells: 2.5" "Low cell type specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040415 Approved NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 2: Non-specific - Mixed function" "Cluster 27: Non-specific - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 97: Non-specific - Cellular respiration" 14 "HPA040415: " "unprognostic (1.47e-3)" "unprognostic (2.23e-1)" "unprognostic (2.36e-1)" "unprognostic (1.03e-2)" "unprognostic (2.44e-1)" "unprognostic (2.28e-1)" "unprognostic (2.82e-1)" "potential prognostic favorable (2.11e-5)" "potential prognostic unfavorable (1.14e-4)" "unprognostic (9.10e-2)" "potential prognostic favorable (2.05e-6)" "unprognostic (2.48e-3)" "unprognostic (5.30e-3)" "unprognostic (9.75e-3)" "unprognostic (1.75e-3)" "unprognostic (2.39e-1)" "unprognostic (7.95e-2)" "unprognostic (1.11e-1)" "unprognostic (2.40e-1)" "unprognostic (2.11e-1)" "unprognostic (1.81e-2)" "unprognostic (2.61e-1)" "unprognostic (3.38e-2)" "unprognostic (1.08e-1)" "unprognostic (6.86e-2)" "unprognostic (4.91e-2)" "unprognostic (1.94e-1)" "unprognostic (6.20e-2)" "unprognostic (3.31e-1)" "unprognostic (2.17e-1)" "unprognostic (3.28e-2)" VPS35 "FLJ10752, MEM3, PARK17" ENSG00000069329 "VPS35 retromer complex component" Q96QK1 16 46656132-46689518 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Host-virus interaction, Protein transport, Transport" "Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040802 Supported Approved Endosomes,Lysosomes NA NA 520000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 40: Non-specific - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 6: Leukemia - Signal transduction" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 105 "Endosomes, Lysosomes" "HPA040802: " "unprognostic (9.55e-2)" "unprognostic (1.85e-2)" "unprognostic (2.08e-1)" "unprognostic (1.62e-1)" "unprognostic (9.55e-2)" "unprognostic (5.97e-2)" "unprognostic (6.58e-2)" "unprognostic (1.18e-1)" "unprognostic (2.14e-2)" "unprognostic (1.57e-1)" "unprognostic (2.38e-3)" "unprognostic (5.08e-2)" "unprognostic (3.68e-3)" "unprognostic (1.47e-1)" "unprognostic (8.27e-2)" "unprognostic (6.05e-2)" "unprognostic (1.89e-1)" "unprognostic (5.64e-3)" "unprognostic (2.98e-2)" "unprognostic (9.97e-2)" "unprognostic (4.05e-2)" "unprognostic (3.36e-3)" "unprognostic (1.03e-1)" "unprognostic (2.17e-1)" "unprognostic (1.52e-2)" "unprognostic (8.13e-2)" "unprognostic (3.39e-3)" VPS35L "C16orf62, MGC16824" ENSG00000103544 "VPS35 endosomal protein sorting factor like" Q7Z3J2 16 19555240-19706793 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 594.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Fibroblasts, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042969, HPA053547" Uncertain Approved Mitochondria NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 61: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 54: Non-specific - Transcription" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 44 Mitochondria "HPA042969: , HPA053547: " "unprognostic (9.59e-3)" "unprognostic (2.04e-1)" "unprognostic (2.35e-1)" "unprognostic (1.00e-1)" "unprognostic (2.18e-3)" "unprognostic (1.24e-1)" "unprognostic (2.20e-2)" "unprognostic (2.69e-1)" "unprognostic (1.03e-1)" "potential prognostic favorable (8.17e-9)" "unprognostic (4.03e-3)" "unprognostic (1.20e-2)" "unprognostic (1.35e-2)" "unprognostic (2.32e-2)" "unprognostic (5.59e-2)" "unprognostic (2.56e-1)" "unprognostic (1.05e-1)" "unprognostic (6.57e-2)" "unprognostic (4.00e-2)" "unprognostic (7.74e-2)" "unprognostic (2.46e-2)" "unprognostic (2.23e-1)" "unprognostic (2.44e-1)" "unprognostic (2.34e-1)" "unprognostic (7.44e-2)" "potential prognostic unfavorable (4.53e-4)" "unprognostic (2.37e-1)" "unprognostic (8.86e-2)" "unprognostic (7.37e-2)" VPS36 "C13orf9, CGI-145, Eap45" ENSG00000136100 "Vacuolar protein sorting 36 homolog" Q86VN1 13 52412602-52450634 "Essential proteins, Predicted intracellular proteins" "Protein transport, Transcription, Transcription regulation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Rod photoreceptor cells: 253.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039734, HPA043947" Approved Supported "Vesicles,Lysosomes,Plasma membrane,Cell Junctions" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" 17 "Vesicles, Lysosomes" "Plasma membrane, Cell Junctions" "HPA039734: , HPA043947: " "unprognostic (1.58e-1)" "unprognostic (1.96e-1)" "unprognostic (1.15e-2)" "unprognostic (5.53e-2)" "unprognostic (3.54e-1)" "unprognostic (1.34e-2)" "unprognostic (4.94e-1)" "unprognostic (8.25e-2)" "unprognostic (2.20e-1)" "unprognostic (5.70e-2)" "potential prognostic favorable (4.82e-8)" "unprognostic (4.62e-3)" "unprognostic (1.11e-2)" "unprognostic (2.25e-1)" "unprognostic (3.00e-1)" "unprognostic (5.78e-2)" "unprognostic (9.97e-2)" "unprognostic (4.32e-1)" "unprognostic (1.16e-1)" "unprognostic (7.74e-3)" "unprognostic (2.10e-2)" "unprognostic (4.87e-2)" "unprognostic (1.03e-1)" "unprognostic (2.03e-1)" "unprognostic (3.38e-1)" "unprognostic (1.08e-1)" "unprognostic (2.25e-3)" "unprognostic (1.25e-1)" "unprognostic (4.55e-1)" "unprognostic (2.66e-1)" "unprognostic (2.68e-1)" VPS37A "FLJ32642, HCRP1, PQBP2, SPG53" ENSG00000155975 "VPS37A subunit of ESCRT-I" Q8NEZ2 8 17246931-17302427 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024705, HPA024781" Supported Approved "Nucleoplasm,Vesicles,Centrosome,Cytosol,Acrosome,Equatorial segment,Perinuclear theca,Flagellar centriole,Mid piece,Principal piece,End piece" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 42: Retina - Visual perception" "Cluster 16: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" 32 "Vesicles, Centrosome, Acrosome, Flagellar centriole" "Nucleoplasm, Cytosol, Equatorial segment, Perinuclear theca, Mid piece, Principal piece, End piece" "HPA024705: , HPA024781: " "unprognostic (4.47e-3)" "unprognostic (9.89e-2)" "unprognostic (3.36e-3)" "unprognostic (3.64e-3)" "unprognostic (9.54e-3)" "unprognostic (3.56e-2)" "unprognostic (2.53e-2)" "unprognostic (9.34e-2)" "unprognostic (2.62e-1)" "potential prognostic unfavorable (5.58e-4)" "potential prognostic favorable (2.52e-4)" "unprognostic (7.10e-3)" "unprognostic (8.99e-2)" "unprognostic (1.04e-2)" "unprognostic (1.96e-3)" "unprognostic (4.88e-1)" "unprognostic (2.19e-1)" "unprognostic (3.17e-1)" "unprognostic (7.46e-2)" "unprognostic (1.27e-1)" "unprognostic (6.86e-3)" "unprognostic (8.59e-2)" "unprognostic (1.30e-2)" "unprognostic (2.61e-1)" "unprognostic (3.91e-2)" "unprognostic (5.32e-2)" "unprognostic (1.91e-2)" "unprognostic (4.64e-2)" "unprognostic (2.54e-1)" "unprognostic (1.01e-1)" "unprognostic (3.26e-2)" VPS37B FLJ12750 ENSG00000139722 "VPS37B subunit of ESCRT-I" Q9H9H4 12 122865330-122896127 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 244.2;Esophageal apical cells: 355.5;Neutrophils: 316.7" "Cell type enhanced" "Detected in all" "leukocyte: 80.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038217, HPA038218" Enhanced Uncertain "Primary cilium,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 51: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 103: Non-specific - Basic cellular processes" 47 Cytosol "Primary cilium" "HPA038217: , HPA038218: " "unprognostic (1.23e-1)" "unprognostic (9.35e-2)" "unprognostic (3.26e-1)" "unprognostic (3.55e-2)" "unprognostic (1.53e-1)" "unprognostic (7.09e-3)" "unprognostic (3.27e-1)" "unprognostic (1.54e-2)" "unprognostic (2.26e-1)" "unprognostic (1.36e-1)" "unprognostic (3.60e-3)" "potential prognostic favorable (8.69e-4)" "unprognostic (1.03e-2)" "unprognostic (8.80e-2)" "unprognostic (1.00e-2)" "unprognostic (5.70e-2)" "unprognostic (6.37e-3)" "unprognostic (1.30e-1)" "unprognostic (1.36e-1)" "unprognostic (1.12e-1)" "unprognostic (1.12e-1)" "unprognostic (5.81e-3)" "unprognostic (3.22e-3)" "unprognostic (2.30e-1)" "unprognostic (9.85e-2)" "unprognostic (2.46e-1)" "unprognostic (6.70e-3)" "unprognostic (4.50e-2)" "unprognostic (2.16e-1)" "unprognostic (3.75e-3)" "unprognostic (3.17e-2)" VPS37C FLJ20847 ENSG00000167987 "VPS37C subunit of ESCRT-I" A5D8V6 11 61130257-61161615 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 164.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 1.4;eosinophil: 1.7;intermediate monocyte: 2.6;myeloid DC: 1.0;neutrophil: 3.8;non-classical monocyte: 2.4" "Group enriched" "Detected in many" 5 "dendritic cells: 1.0;granulocytes: 3.8;monocytes: 2.6" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Skin - Keratinocyte (other), Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043348, HPA062233" Approved Enhanced "Nucleoplasm,Golgi apparatus,Vesicles,Primary cilium" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 24: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" 85 "Nucleoplasm, Vesicles" "Golgi apparatus, Primary cilium" "HPA043348: , HPA062233: " "unprognostic (9.06e-2)" "unprognostic (1.50e-1)" "unprognostic (5.34e-2)" "unprognostic (3.33e-2)" "unprognostic (9.36e-2)" "unprognostic (1.22e-2)" "unprognostic (3.58e-1)" "unprognostic (7.67e-2)" "unprognostic (8.88e-2)" "unprognostic (5.50e-2)" "potential prognostic favorable (1.40e-5)" "unprognostic (2.93e-1)" "unprognostic (2.39e-2)" "potential prognostic unfavorable (4.18e-6)" "unprognostic (2.47e-2)" "unprognostic (2.15e-1)" "unprognostic (3.56e-3)" "unprognostic (4.47e-2)" "unprognostic (4.43e-1)" "unprognostic (1.28e-1)" "unprognostic (1.87e-2)" "unprognostic (9.82e-3)" "unprognostic (2.11e-1)" "unprognostic (1.16e-1)" "unprognostic (2.96e-1)" "unprognostic (1.66e-2)" "unprognostic (1.05e-1)" "unprognostic (1.49e-1)" "unprognostic (2.89e-1)" "unprognostic (6.65e-2)" "unprognostic (1.91e-1)" VPS37D "MGC35352, WBSCR24" ENSG00000176428 "VPS37D subunit of ESCRT-I" Q86XT2 7 73667831-73672112 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 12.5" "Cell type enhanced" "Detected in many" "Epididymal clear cells: 30.6;Epididymal efferent duct absorptive cells: 15.4;Epididymal principal cells: 19.3;Pancreatic duct cells: 10.2;Undifferentiated spermatogonia: 12.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040978 Uncertain Approved Vesicles NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 11: Muller glia cells - Retinal homeostasis" 4 Vesicles "HPA040978: " "unprognostic (1.23e-1)" "unprognostic (3.02e-2)" "unprognostic (1.49e-1)" "unprognostic (1.36e-1)" "unprognostic (5.54e-2)" "unprognostic (1.01e-2)" "unprognostic (1.39e-1)" "unprognostic (5.97e-2)" "unprognostic (8.21e-2)" "unprognostic (2.36e-1)" "validated prognostic favorable (3.07e-8)" "validated prognostic favorable (8.03e-5)" "potential prognostic favorable (6.01e-5)" "unprognostic (2.52e-1)" "unprognostic (4.02e-1)" "unprognostic (5.27e-3)" "unprognostic (1.32e-2)" "unprognostic (2.91e-2)" "unprognostic (7.75e-2)" "unprognostic (1.88e-1)" "unprognostic (7.16e-2)" "potential prognostic favorable (9.69e-5)" "unprognostic (2.36e-1)" "unprognostic (7.02e-2)" "unprognostic (8.98e-2)" "unprognostic (2.47e-1)" "unprognostic (3.83e-2)" "unprognostic (1.47e-1)" "unprognostic (1.28e-1)" "unprognostic (1.89e-3)" "unprognostic (1.30e-1)" VPS39 "KIAA0770, VAM6" ENSG00000166887 "VPS39 subunit of HOPS complex" Q96JC1 15 42158701-42208307 "Plasma proteins, Predicted intracellular proteins" "Autophagy, Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 19 "unprognostic (5.18e-2)" "unprognostic (1.39e-2)" "unprognostic (4.75e-2)" "unprognostic (1.71e-2)" "unprognostic (1.98e-1)" "unprognostic (4.76e-2)" "unprognostic (9.18e-2)" "unprognostic (4.67e-3)" "unprognostic (8.50e-2)" "unprognostic (1.34e-2)" "potential prognostic favorable (3.93e-6)" "unprognostic (2.24e-3)" "unprognostic (4.25e-2)" "unprognostic (1.52e-1)" "unprognostic (3.39e-1)" "unprognostic (1.09e-1)" "unprognostic (1.10e-1)" "unprognostic (2.27e-1)" "unprognostic (1.18e-1)" "unprognostic (8.11e-2)" "unprognostic (1.62e-1)" "unprognostic (7.36e-2)" "potential prognostic unfavorable (9.17e-4)" "unprognostic (1.80e-1)" "unprognostic (8.25e-3)" "unprognostic (6.79e-2)" "unprognostic (3.14e-1)" "unprognostic (6.11e-2)" "unprognostic (3.22e-1)" "unprognostic (4.51e-2)" "unprognostic (3.70e-2)" VPS41 HVSP41 ENSG00000006715 "VPS41 subunit of HOPS complex" P49754 7 38722974-38932394 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Autophagy, Protein transport, Transport" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020080, HPA020299" Approved NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 67: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 22 "HPA020080: , HPA020299: " "unprognostic (1.03e-2)" "unprognostic (4.62e-3)" "unprognostic (7.50e-2)" "potential prognostic unfavorable (8.86e-4)" "unprognostic (8.85e-2)" "unprognostic (9.68e-2)" "unprognostic (9.19e-2)" "unprognostic (7.34e-2)" "unprognostic (5.65e-2)" "unprognostic (5.64e-3)" "potential prognostic favorable (9.49e-8)" "unprognostic (3.40e-3)" "unprognostic (2.75e-2)" "unprognostic (2.75e-1)" "unprognostic (6.07e-2)" "unprognostic (2.63e-1)" "unprognostic (3.73e-1)" "unprognostic (5.73e-2)" "unprognostic (3.44e-1)" "unprognostic (7.76e-2)" "potential prognostic unfavorable (2.95e-4)" "unprognostic (3.17e-2)" "unprognostic (6.72e-2)" "unprognostic (1.08e-1)" "unprognostic (2.19e-2)" "unprognostic (9.22e-2)" "unprognostic (1.22e-1)" "unprognostic (8.46e-3)" "unprognostic (3.87e-1)" "unprognostic (3.99e-2)" "unprognostic (3.32e-1)" VPS45 "h-vps45, H1, VPS45A, VPS45B" ENSG00000136631 "Vacuolar protein sorting 45 homolog" Q9NRW7 1 150067279-150145329 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 245.3;Early spermatids: 271.6;Late spermatids: 397.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027425, HPA027441" Uncertain Approved Microtubules NA NA 7700 "Cluster 33: Non-specific - ATP binding" "Cluster 74: Non-specific - Signal transduction" "Cluster 31: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 52 Microtubules "HPA027425: , HPA027441: " "unprognostic (3.44e-2)" "unprognostic (9.99e-3)" "unprognostic (6.28e-2)" "unprognostic (2.03e-2)" "unprognostic (1.52e-1)" "unprognostic (7.92e-2)" "unprognostic (1.53e-1)" "potential prognostic favorable (5.51e-4)" "unprognostic (1.55e-2)" "unprognostic (8.46e-2)" "unprognostic (1.73e-2)" "unprognostic (2.16e-1)" "unprognostic (7.70e-2)" "potential prognostic unfavorable (5.55e-5)" "unprognostic (4.56e-2)" "unprognostic (2.32e-1)" "unprognostic (9.58e-2)" "unprognostic (8.75e-3)" "unprognostic (1.52e-1)" "unprognostic (8.56e-2)" "unprognostic (2.95e-1)" "unprognostic (5.85e-1)" "unprognostic (1.33e-1)" "unprognostic (5.02e-2)" "unprognostic (2.27e-2)" "unprognostic (9.52e-2)" "unprognostic (2.98e-2)" "unprognostic (1.66e-1)" "unprognostic (2.02e-1)" "unprognostic (3.75e-1)" "unprognostic (1.95e-1)" VPS4A "FLJ22197, SKD1, SKD1A, SKD2, VPS4, VPS4-1" ENSG00000132612 "Vacuolar protein sorting 4 homolog A" Q9UN37 16 69311350-69326939 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Protein transport, Transport" Hydrolase "Cataract, Congenital dyserythropoietic anemia, Disease variant, Hereditary hemolytic anemia, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 135.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018751, CAB034411, HPA060092" Approved Supported Midbody Yes NA "Cluster 25: Non-specific - Unknown function" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 97: Non-specific - Cellular respiration" 36 Midbody "CAB018751: , CAB034411: , HPA060092: " "unprognostic (2.00e-1)" "unprognostic (1.70e-2)" "unprognostic (1.57e-1)" "unprognostic (5.27e-2)" "unprognostic (9.45e-2)" "unprognostic (1.21e-1)" "unprognostic (2.52e-1)" "potential prognostic favorable (9.83e-6)" "unprognostic (2.38e-2)" "unprognostic (1.06e-1)" "potential prognostic favorable (1.99e-6)" "unprognostic (2.38e-2)" "potential prognostic favorable (9.79e-4)" "unprognostic (4.09e-3)" "unprognostic (1.51e-1)" "unprognostic (8.49e-2)" "unprognostic (1.41e-2)" "unprognostic (2.86e-3)" "unprognostic (1.52e-2)" "unprognostic (2.85e-2)" "unprognostic (9.38e-2)" "unprognostic (1.06e-1)" "unprognostic (3.15e-1)" "unprognostic (1.78e-2)" "unprognostic (2.23e-2)" "unprognostic (2.03e-1)" "unprognostic (2.17e-1)" "unprognostic (2.93e-1)" "unprognostic (2.57e-1)" "unprognostic (1.12e-2)" "unprognostic (2.11e-1)" VPS4B "SKD1, SKD1B, VPS4-2" ENSG00000119541 "Vacuolar protein sorting 4 homolog B" O75351 18 63389190-63422483 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1139.3;Neutrophils: 356.8;Ocular epithelial cells: 427.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040393, CAB046445, HPA057649" Approved Approved Vesicles No No 32000 "Cluster 35: Neutrophils - Protein binding" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 100: Stratified epithelial cells - Barrier functions" 15 Vesicles "CAB046445: , HPA040393: , HPA057649: " "unprognostic (6.08e-2)" "unprognostic (3.01e-2)" "unprognostic (2.19e-2)" "unprognostic (7.62e-3)" "unprognostic (2.95e-2)" "unprognostic (4.81e-2)" "unprognostic (2.07e-1)" "unprognostic (1.22e-1)" "unprognostic (1.06e-1)" "unprognostic (3.22e-2)" "validated prognostic favorable (2.14e-7)" "validated prognostic favorable (8.77e-4)" "unprognostic (4.58e-2)" "unprognostic (1.55e-1)" "unprognostic (6.86e-2)" "unprognostic (1.14e-2)" "unprognostic (2.55e-1)" "unprognostic (4.79e-2)" "unprognostic (7.22e-2)" "unprognostic (4.45e-2)" "unprognostic (1.82e-3)" "unprognostic (1.72e-3)" "unprognostic (2.55e-1)" "unprognostic (2.27e-1)" "unprognostic (3.32e-2)" "unprognostic (2.61e-2)" "unprognostic (2.32e-2)" "unprognostic (2.62e-1)" "unprognostic (3.84e-1)" "unprognostic (1.21e-1)" "unprognostic (8.17e-2)" VPS50 "CCDC132, DKFZp313I2429, FLJ20097, KIAA1861, VPS54L" ENSG00000004766 "VPS50 subunit of EARP/GARPII complex" Q96JG6 7 93232340-93361123 "Disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Epilepsy, Intellectual disability, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026679 Approved Uncertain "Plasma membrane,Primary cilium,Basal body,Cytosol,Mid piece,Principal piece,End piece" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 39: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 18 "Plasma membrane, Cytosol" "Primary cilium, Basal body, Mid piece, Principal piece, End piece" "HPA026679: " "unprognostic (6.62e-2)" "unprognostic (1.05e-1)" "unprognostic (1.58e-2)" "potential prognostic unfavorable (6.08e-4)" "unprognostic (1.34e-2)" "unprognostic (8.82e-2)" "unprognostic (9.67e-3)" "unprognostic (1.57e-2)" "unprognostic (1.02e-2)" "unprognostic (1.94e-1)" "unprognostic (4.20e-3)" "unprognostic (8.52e-3)" "potential prognostic unfavorable (2.03e-6)" "unprognostic (2.41e-1)" "unprognostic (1.99e-1)" "unprognostic (2.75e-1)" "unprognostic (1.30e-1)" "unprognostic (1.30e-2)" "unprognostic (2.62e-2)" "unprognostic (2.22e-1)" "unprognostic (2.21e-2)" "unprognostic (1.42e-1)" "unprognostic (3.06e-1)" "unprognostic (3.79e-1)" "unprognostic (9.41e-3)" "unprognostic (1.82e-1)" "unprognostic (3.60e-1)" "unprognostic (2.09e-2)" "unprognostic (1.38e-1)" VPS51 "ANG2, ANG3, C11orf2, C11orf3, FFR" ENSG00000149823 "VPS51 subunit of GARP complex" Q9UID3 11 65089324-65111862 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Lipid transport, Protein transport, Transport" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 374.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039650, HPA061447" Uncertain Approved "Nucleoli,Golgi apparatus,Vesicles" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 24: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 27 "Golgi apparatus, Vesicles" Nucleoli "HPA039650: , HPA061447: " "unprognostic (2.77e-1)" "unprognostic (2.72e-1)" "unprognostic (1.49e-3)" "unprognostic (2.54e-2)" "unprognostic (7.50e-2)" "unprognostic (2.21e-2)" "unprognostic (2.68e-2)" "unprognostic (1.43e-1)" "unprognostic (1.14e-1)" "potential prognostic favorable (2.37e-10)" "unprognostic (6.44e-2)" "unprognostic (2.72e-3)" "unprognostic (1.49e-2)" "unprognostic (1.06e-1)" "unprognostic (8.10e-3)" "unprognostic (2.78e-3)" "unprognostic (2.00e-1)" "unprognostic (8.72e-2)" "unprognostic (1.19e-1)" "unprognostic (1.15e-1)" "unprognostic (8.95e-2)" "unprognostic (1.37e-1)" "unprognostic (2.42e-3)" "unprognostic (1.24e-1)" "unprognostic (2.58e-1)" "unprognostic (2.85e-3)" "unprognostic (9.32e-2)" "unprognostic (1.07e-1)" "unprognostic (5.91e-2)" VPS52 "ARE1, SACM2L" ENSG00000223501 "VPS52 subunit of GARP complex" Q8N1B4 6 33250272-33272047 "Essential proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 25.9;Bergmann glia: 26.6;Brain excitatory neurons: 15.9;Brain inhibitory neurons: 15.5;Choroid plexus epithelial cells: 20.8;Distal convoluted tubule cells: 22.7;Ependymal cells: 18.8;Loop of henle epithelial cells: 19.8;Microglia: 23.3;Oligodendrocyte progenitor cells: 18.1;Oligodendrocytes: 27.2;Podocytes: 21.2;Proximal tubule cells: 20.6;Renal collecting duct intercalated cells: 18.6;Renal collecting duct principal cells: 17.3;Renal connecting tubule cells: 18.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042667, HPA048128" Approved NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 24: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 27: Breast cancer - Unknown function" "Cluster 102: Non-specific - Mixed function" 107 "HPA042667: , HPA048128: " "unprognostic (2.93e-2)" "unprognostic (3.72e-2)" "unprognostic (2.06e-1)" "unprognostic (2.07e-2)" "unprognostic (2.53e-1)" "unprognostic (6.33e-2)" "unprognostic (2.16e-3)" "unprognostic (5.31e-3)" "unprognostic (2.66e-1)" "unprognostic (4.35e-2)" "potential prognostic favorable (2.97e-4)" "unprognostic (3.69e-1)" "unprognostic (1.59e-1)" "potential prognostic unfavorable (7.19e-4)" "unprognostic (1.48e-1)" "unprognostic (2.14e-1)" "unprognostic (1.63e-1)" "unprognostic (1.92e-3)" "unprognostic (1.44e-2)" "unprognostic (1.23e-1)" "unprognostic (2.33e-1)" "unprognostic (3.38e-1)" "unprognostic (4.80e-2)" "unprognostic (1.80e-2)" "unprognostic (1.37e-1)" "unprognostic (1.81e-3)" "unprognostic (2.75e-2)" "unprognostic (2.61e-1)" "unprognostic (1.38e-2)" "unprognostic (1.96e-1)" "unprognostic (1.89e-1)" VPS53 "FLJ10979, HCCS1" ENSG00000141252 "VPS53 subunit of GARP complex" Q5VIR6 17 508503-721717 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant, Epilepsy, Intellectual disability, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 119.4;Bergmann glia: 108.0;Brain excitatory neurons: 186.7;Brain inhibitory neurons: 148.8;Choroid plexus epithelial cells: 218.5;Distal convoluted tubule cells: 153.6;Early spermatids: 264.9;Ependymal cells: 244.7;Late spermatids: 246.7;Loop of henle epithelial cells: 139.7;Microglia: 110.4;Oligodendrocytes: 108.9;Other brain neurons: 138.6;Papillary tip epithelial cells: 138.4;Podocytes: 123.4;Proximal tubule cells: 143.5;Renal collecting duct intercalated cells: 166.3;Renal collecting duct principal cells: 173.6;Renal connecting tubule cells: 168.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022988, HPA024446" Approved Supported "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 15: Non-specific - Transcription" "Cluster 42: Non-specific - Unknown function" "Cluster 102: Non-specific - Mixed function" 13 "Golgi apparatus, Vesicles" Cytosol "HPA022988: , HPA024446: " "unprognostic (6.40e-2)" "unprognostic (9.00e-2)" "unprognostic (1.71e-1)" "unprognostic (3.37e-2)" "unprognostic (6.70e-2)" "unprognostic (2.08e-1)" "unprognostic (1.50e-1)" "unprognostic (1.02e-2)" "unprognostic (6.85e-2)" "unprognostic (1.89e-3)" "unprognostic (2.13e-1)" "potential prognostic favorable (1.33e-4)" "unprognostic (7.84e-2)" "unprognostic (1.26e-3)" "unprognostic (1.12e-1)" "unprognostic (1.17e-1)" "unprognostic (1.67e-2)" "unprognostic (3.53e-2)" "unprognostic (2.39e-2)" "unprognostic (1.76e-1)" "unprognostic (5.24e-2)" "unprognostic (4.95e-2)" "unprognostic (7.93e-2)" "unprognostic (1.52e-1)" "unprognostic (1.90e-2)" "unprognostic (8.95e-2)" "unprognostic (1.28e-1)" "unprognostic (1.95e-1)" "unprognostic (2.37e-1)" "potential prognostic unfavorable (3.00e-4)" "unprognostic (5.08e-2)" VPS54 "HCC8, PPP1R164" ENSG00000143952 "VPS54 subunit of GARP complex" Q9P1Q0 2 63892146-64019428 "Essential proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epicardial cells: 709.5;Neutrophil progenitors: 581.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055894, HPA067981, HPA070582" Enhanced "Nucleoplasm,Golgi apparatus" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 18: Liver cancer - Metabolism" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 7 "Golgi apparatus" Nucleoplasm "HPA055894: , HPA067981: , HPA070582: " "unprognostic (5.35e-2)" "unprognostic (1.62e-1)" "unprognostic (1.24e-1)" "unprognostic (4.18e-2)" "unprognostic (1.35e-1)" "unprognostic (3.30e-2)" "unprognostic (3.60e-1)" "unprognostic (4.78e-2)" "unprognostic (4.59e-3)" "unprognostic (2.89e-2)" "potential prognostic favorable (8.55e-7)" "unprognostic (4.57e-2)" "unprognostic (2.93e-1)" "unprognostic (3.07e-3)" "unprognostic (7.39e-3)" "unprognostic (2.23e-1)" "unprognostic (2.29e-1)" "unprognostic (2.01e-2)" "unprognostic (1.82e-1)" "unprognostic (3.90e-2)" "unprognostic (1.08e-1)" "unprognostic (6.19e-2)" "unprognostic (4.21e-2)" "unprognostic (5.41e-1)" "unprognostic (8.77e-2)" "unprognostic (2.29e-2)" "unprognostic (6.71e-2)" "unprognostic (5.80e-2)" "unprognostic (1.86e-1)" "unprognostic (1.27e-2)" "unprognostic (2.66e-1)" VPS72 "Swc2, TCFL1, YL-1, YL1" ENSG00000163159 "Vacuolar protein sorting 72 homolog" Q15906 1 151176304-151195321 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 211.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065709 Supported "Nuclear speckles" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 24: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 97: Non-specific - Cellular respiration" 54 "Nuclear speckles" "HPA065709: " "unprognostic (7.82e-2)" "unprognostic (9.82e-2)" "unprognostic (4.93e-2)" "unprognostic (1.25e-2)" "unprognostic (1.75e-1)" "unprognostic (7.85e-2)" "unprognostic (4.51e-2)" "potential prognostic favorable (2.31e-4)" "unprognostic (4.27e-3)" "unprognostic (1.43e-3)" "unprognostic (5.84e-3)" "unprognostic (5.30e-2)" "unprognostic (9.64e-3)" "potential prognostic unfavorable (2.87e-5)" "unprognostic (1.08e-3)" "unprognostic (2.45e-2)" "unprognostic (7.87e-2)" "unprognostic (9.44e-2)" "unprognostic (1.47e-2)" "unprognostic (3.55e-2)" "unprognostic (1.10e-1)" "unprognostic (2.76e-1)" "unprognostic (2.78e-2)" "unprognostic (6.05e-2)" "unprognostic (1.25e-1)" "unprognostic (8.34e-2)" "unprognostic (1.49e-2)" "unprognostic (8.14e-2)" "unprognostic (1.49e-1)" "unprognostic (2.29e-1)" "unprognostic (2.51e-1)" VPS8 "FLJ32099, KIAA0804" ENSG00000156931 "VPS8 subunit of CORVET complex" Q8N3P4 3 184812143-185052614 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 633.1;Neutrophil progenitors: 461.3;Neutrophils: 1316.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036871 Uncertain NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 63: Non-specific - Protein processing" "Cluster 24: Neutrophils - Innate immunity signal integration" 21 "HPA036871: " "unprognostic (5.12e-1)" "unprognostic (4.94e-2)" "unprognostic (1.74e-1)" "unprognostic (2.54e-1)" "unprognostic (1.91e-1)" "unprognostic (1.43e-1)" "unprognostic (6.52e-2)" "unprognostic (1.81e-2)" "unprognostic (1.57e-2)" "potential prognostic unfavorable (4.74e-7)" "validated prognostic favorable (8.99e-4)" "validated prognostic favorable (7.88e-4)" "unprognostic (1.62e-2)" "unprognostic (1.33e-3)" "unprognostic (2.28e-1)" "unprognostic (1.88e-1)" "unprognostic (6.87e-3)" "unprognostic (1.10e-2)" "unprognostic (3.36e-3)" "unprognostic (5.45e-2)" "unprognostic (6.21e-2)" "unprognostic (1.57e-1)" "unprognostic (1.48e-3)" "unprognostic (1.47e-1)" "unprognostic (5.33e-2)" "unprognostic (3.70e-1)" "unprognostic (1.21e-1)" "unprognostic (2.45e-1)" "unprognostic (2.84e-1)" "unprognostic (7.01e-3)" "unprognostic (4.04e-1)" VPS9D1 "ATP-BL, C16orf7" ENSG00000075399 "VPS9 domain containing 1" Q9Y2B5 16 89707134-89720898 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 193.3;Retinal ganglion cells: 100.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 8 "neutrophil: 18.1" "Lineage enriched" "Detected in single" 26 "granulocytes: 18.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007847, HPA023620" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 64: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 24: Neutrophils - Innate immunity signal integration" 26 Cytosol Nucleoplasm "HPA007847: , HPA023620: " "unprognostic (5.97e-3)" "unprognostic (1.72e-1)" "unprognostic (3.81e-1)" "unprognostic (3.21e-2)" "unprognostic (4.60e-2)" "unprognostic (2.08e-1)" "unprognostic (1.14e-2)" "unprognostic (1.27e-1)" "unprognostic (6.00e-2)" "unprognostic (1.39e-3)" "potential prognostic unfavorable (2.88e-5)" "potential prognostic favorable (4.19e-5)" "unprognostic (7.02e-2)" "unprognostic (2.13e-1)" "unprognostic (3.62e-2)" "unprognostic (2.47e-2)" "unprognostic (2.98e-1)" "unprognostic (1.74e-1)" "unprognostic (5.17e-2)" "unprognostic (4.99e-3)" "unprognostic (4.18e-2)" "unprognostic (6.50e-2)" "unprognostic (3.23e-1)" "unprognostic (1.16e-1)" "unprognostic (2.02e-1)" "unprognostic (3.49e-2)" "unprognostic (2.25e-1)" "unprognostic (9.27e-2)" "unprognostic (1.13e-1)" VRK1 ENSG00000100749 "VRK serine/threonine kinase 1" Q99986 14 96797304-96954846 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Host-virus interaction, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 48.2" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 152.4;Early primary spermatocytes: 281.9;Erythrocyte progenitors: 268.2;Monocyte progenitors: 177.4;Neutrophil progenitors: 331.0;Oocytes: 345.4;Parietal cells: 353.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Mitotic cells (Spleen), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000660, HPA017929" Enhanced Supported Nucleoplasm,Cytosol Yes No "Cluster 5: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 34: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 58 Nucleoplasm Cytosol "HPA000660: , HPA017929: " "potential prognostic unfavorable (7.24e-4)" "unprognostic (2.49e-1)" "unprognostic (3.92e-2)" "unprognostic (3.67e-3)" "unprognostic (5.40e-2)" "unprognostic (9.25e-2)" "unprognostic (1.65e-1)" "unprognostic (1.93e-2)" "unprognostic (9.60e-3)" "unprognostic (2.93e-2)" "potential prognostic favorable (2.03e-7)" "unprognostic (1.64e-1)" "unprognostic (3.74e-2)" "validated prognostic unfavorable (2.59e-5)" "validated prognostic unfavorable (5.95e-5)" "unprognostic (2.72e-2)" "unprognostic (4.24e-3)" "potential prognostic favorable (1.32e-4)" "unprognostic (6.78e-2)" "unprognostic (1.74e-1)" "unprognostic (3.99e-3)" "unprognostic (7.19e-2)" "unprognostic (2.35e-3)" "unprognostic (2.50e-1)" "unprognostic (7.49e-2)" "unprognostic (8.63e-2)" "unprognostic (2.32e-1)" "unprognostic (1.80e-1)" "unprognostic (2.50e-1)" "unprognostic (1.93e-1)" "unprognostic (1.17e-1)" VRK2 ENSG00000028116 "VRK serine/threonine kinase 2" Q86Y07 2 57907629-58159920 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 578.1;Oligodendrocytes: 494.8" "Cell type enhanced" "Detected in all" "oligodendrocyte: 659.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046459, HPA047503" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 80: Oligodendrocytes - Myelination" 37 "Endoplasmic reticulum" "CAB046459: , HPA047503: " "unprognostic (9.73e-2)" "unprognostic (1.53e-1)" "unprognostic (4.39e-1)" "unprognostic (1.69e-2)" "unprognostic (1.00e-1)" "unprognostic (1.34e-1)" "unprognostic (1.01e-1)" "unprognostic (3.01e-2)" "unprognostic (1.22e-2)" "potential prognostic unfavorable (6.04e-4)" "unprognostic (4.47e-2)" "unprognostic (5.75e-1)" "unprognostic (3.86e-2)" "potential prognostic unfavorable (2.71e-7)" "unprognostic (1.32e-2)" "potential prognostic unfavorable (1.83e-4)" "unprognostic (1.87e-2)" "unprognostic (1.69e-1)" "unprognostic (2.58e-1)" "unprognostic (2.40e-1)" "unprognostic (4.09e-1)" "unprognostic (2.09e-3)" "potential prognostic unfavorable (1.18e-4)" "unprognostic (2.06e-1)" "unprognostic (9.05e-3)" "unprognostic (1.42e-1)" "unprognostic (2.22e-2)" "unprognostic (2.65e-1)" "unprognostic (2.99e-1)" "unprognostic (1.41e-1)" "unprognostic (1.17e-1)" VRK3 ENSG00000105053 "VRK serine/threonine kinase 3" Q8IV63 19 49976468-50025946 "Enzymes, Plasma proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 128.9" "Cell type enriched" "Detected in many" 4 "Late spermatids: 2917.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056489 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 47: Testis - Mixed function" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 55: Lymphoma - Immune response" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 12 "Nucleoplasm, Vesicles" "HPA056489: " "unprognostic (4.56e-2)" "unprognostic (1.01e-1)" "unprognostic (2.10e-1)" "unprognostic (1.59e-1)" "unprognostic (8.42e-2)" "unprognostic (2.25e-1)" "unprognostic (2.20e-1)" "unprognostic (9.71e-2)" "unprognostic (9.31e-2)" "unprognostic (3.48e-2)" "potential prognostic favorable (1.64e-5)" "unprognostic (4.56e-2)" "unprognostic (3.42e-2)" "unprognostic (3.54e-2)" "unprognostic (6.16e-2)" "unprognostic (1.48e-2)" "unprognostic (1.75e-1)" "unprognostic (7.52e-2)" "unprognostic (4.27e-1)" "unprognostic (1.34e-1)" "unprognostic (6.25e-2)" "unprognostic (5.70e-3)" "unprognostic (2.02e-1)" "unprognostic (3.04e-1)" "unprognostic (1.04e-1)" "unprognostic (1.27e-1)" "unprognostic (8.46e-3)" "unprognostic (1.51e-1)" "unprognostic (1.47e-1)" "unprognostic (8.02e-3)" "unprognostic (3.21e-2)" VRTN "C14orf115, FLJ10811, vertnin" ENSG00000133980 "Vertebrae development associated" Q9H8Y1 14 74303069-74360008 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 1.4;testis: 1.6" "Cell type enhanced" "Detected in some" "Breast lactating cells: 3.4;Differentiating spermatogonia: 3.2;Early primary spermatocytes: 5.8;Early spermatids: 3.7;Epididymal principal cells: 4.4;Mucous neck cells: 3.1;Oocytes: 9.2;Paneth cells: 3.9;Tuft cells: 11.5;Undifferentiated spermatogonia: 3.5" "Low cell type specificity" "Detected in some" "Cancer enriched" "Detected in single" 39 "Testicular Germ Cell Tumor (TCGA): 30.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "testis cancer: 8.8" "Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA001460 Uncertain Approved Nucleoplasm NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 9 Nucleoplasm "HPA001460: " "unprognostic (6.16e-2)" VSIG1 "GPA34, MGC44287" ENSG00000101842 "V-set and immunoglobulin domain containing 1" Q86XK7 X 108044970-108079184 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "stomach 1: 182.7" "Cell type enhanced" "Detected in some" "Foveolar cells: 668.5;Gastric chief cells: 105.9;Mucous neck cells: 176.6;Parietal cells: 68.9;Pituitary stem cells: 42.6;Sertoli cells: 106.8" "Cell type enhanced" "Detected in many" "leukocyte: 10.6" "Group enriched" "Detected in many" 15 "Lung Adenocarcinoma (TCGA): 26.5;Pancreatic Adenocarcinoma (TCGA): 29.0;Stomach Adenocarcinoma (TCGA): 51.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 12.0;T-reg: 13.0" "Lineage enriched" "Detected in many" 5 "T-cells: 13.0" "Cancer enhanced" "Detected in some" "Gastric cancer: 9.2;liver cancer: 16.3;pancreatic cancer: 8.0" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "medulla oblongata: 11.5;spinal cord: 27.4" "HPA001445, HPA036310, HPA036311" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 60: Stomach - Digestion" "Cluster 53: Neurons - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 68: Foveolar cells - Mucosal defense" 4 "Vesicles, Cytosol" "HPA001445: , HPA036310: , HPA036311: " "unprognostic (2.49e-1)" "unprognostic (1.35e-1)" "unprognostic (5.04e-2)" "unprognostic (8.70e-3)" "unprognostic (3.75e-2)" "unprognostic (8.51e-3)" "unprognostic (3.48e-2)" "unprognostic (3.74e-2)" "unprognostic (6.90e-3)" "unprognostic (4.45e-2)" "unprognostic (3.94e-3)" "unprognostic (4.44e-2)" "unprognostic (1.02e-1)" "unprognostic (1.60e-2)" "unprognostic (1.42e-2)" "unprognostic (2.80e-2)" "unprognostic (6.63e-2)" "unprognostic (2.38e-1)" "unprognostic (1.24e-2)" VSIG10 ENSG00000176834 "V-set and immunoglobulin domain containing 10" Q8N0Z9 12 118063593-118136026 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Enterocytes: 156.1;Esophageal apical cells: 153.4;Sertoli cells: 158.9" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 39.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA062022 Enhanced Approved "Centriolar satellite,Cytosol" NA NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 19: Astrocytes - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 1: Enterocytes - Absorption and Digestion" Cytosol "Centriolar satellite" "HPA062022: " "unprognostic (2.21e-2)" "unprognostic (4.03e-2)" "unprognostic (1.35e-1)" "unprognostic (1.43e-1)" "unprognostic (2.40e-1)" "unprognostic (7.09e-2)" "unprognostic (1.23e-1)" "unprognostic (3.16e-1)" "unprognostic (1.54e-1)" "unprognostic (1.28e-2)" "unprognostic (3.77e-3)" "unprognostic (1.02e-3)" "unprognostic (3.38e-2)" "potential prognostic unfavorable (9.06e-7)" "unprognostic (1.56e-1)" "unprognostic (1.17e-1)" "unprognostic (1.03e-2)" "unprognostic (6.06e-2)" "unprognostic (1.83e-1)" "unprognostic (9.50e-2)" "unprognostic (1.92e-1)" "unprognostic (2.44e-1)" "unprognostic (1.39e-1)" "unprognostic (8.65e-2)" "unprognostic (1.89e-1)" "unprognostic (1.31e-1)" "unprognostic (8.71e-3)" "unprognostic (2.27e-2)" "unprognostic (1.60e-1)" "unprognostic (3.24e-1)" "unprognostic (1.32e-2)" VSIG10L ENSG00000186806 "V-set and immunoglobulin domain containing 10 like" Q86VR7 19 51331536-51342139 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 69.2;salivary gland: 24.9;vagina: 25.5" "Cell type enriched" "Detected in many" 12 "Esophageal apical cells: 1032.8" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 7.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 6.8" "Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA060453, HPA066745" Uncertain Approved Nucleoplasm NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" Nucleoplasm "HPA060453: , HPA066745: " "unprognostic (2.84e-2)" "unprognostic (4.15e-2)" "unprognostic (2.34e-1)" "unprognostic (9.54e-2)" "unprognostic (6.13e-2)" "unprognostic (6.43e-3)" "unprognostic (2.45e-1)" "unprognostic (6.68e-3)" "unprognostic (2.49e-1)" "unprognostic (1.98e-1)" "unprognostic (1.06e-1)" "unprognostic (5.33e-2)" "unprognostic (2.43e-2)" "unprognostic (1.64e-1)" "unprognostic (1.57e-1)" "unprognostic (2.99e-1)" VSIG10L2 ENSG00000283703 "V-set and immunoglobulin domain containing 10 like 2" P0DP72 11 125946044-125958647 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 4 "brain: 4.4;skin 1: 17.4" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 16.4;Breast hormone-responsive cells: 23.5;Conjunctival goblet cells: 15.5;Epicardial cells: 127.4;Fibro-adipogenic progenitors: 15.9;Mesothelial cells: 32.2;Suprabasal keratinocytes: 21.1" "Cell type enhanced" "Detected in some" "mammillary body: 1.3;upper rhombic lip: 2.2" "Cancer enhanced" "Detected in some" "Prostate Adenocarcinoma (TCGA): 1.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Prostate - Urothelial cells, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 37: Skin - Keratinization" "Cluster 35: Non-specific - DNA binding" "Cluster 27: Breast cancer - Unknown function" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" "unprognostic (1.66e-3)" "unprognostic (1.71e-1)" "unprognostic (3.34e-1)" VSIG2 "CTH, CTXL" ENSG00000019102 "V-set and immunoglobulin domain containing 2" Q96IQ7 11 124747474-124752255 "Predicted membrane proteins" "Lipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "stomach 1: 584.2" "Cell type enhanced" "Detected in many" "Colonocytes: 472.6;Esophageal apical cells: 398.5;Foveolar cells: 956.4;Gastric chief cells: 345.1;Goblet cells: 250.5;Mucous neck cells: 242.1;Parietal cells: 1023.6;Prostatic club cells: 292.8;Prostatic hillock cells: 166.6;Urothelial cells: 371.4" "Group enriched" "Detected in some" 24 "endothelial cell: 18.6;pericyte: 11.1;vascular associated smooth muscle cell: 7.3" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 121.9;Pancreatic Adenocarcinoma (TCGA): 124.3" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Gastric cancer: 19.0" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Liver - Cholangiocytes, Lung - Alveolar cells type 1, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA035919, HPA050147" Enhanced Approved Nucleoplasm NA NA "Cluster 17: Intestine - Digestion" "Cluster 53: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 68: Foveolar cells - Mucosal defense" 5 Nucleoplasm "HPA035919: , HPA050147: " "unprognostic (1.76e-3)" "unprognostic (7.31e-3)" "unprognostic (1.41e-2)" "unprognostic (3.46e-2)" "unprognostic (1.97e-2)" "unprognostic (1.17e-1)" "unprognostic (2.82e-1)" "unprognostic (9.89e-3)" "unprognostic (5.53e-3)" "unprognostic (1.04e-2)" "unprognostic (2.49e-1)" "potential prognostic favorable (2.49e-4)" "unprognostic (5.72e-2)" "unprognostic (3.99e-1)" "potential prognostic favorable (6.09e-4)" "unprognostic (3.07e-3)" "unprognostic (6.65e-2)" "unprognostic (3.19e-2)" "unprognostic (3.39e-1)" "unprognostic (2.86e-1)" "unprognostic (2.46e-1)" "unprognostic (5.46e-2)" "unprognostic (7.49e-3)" "unprognostic (9.49e-2)" "unprognostic (2.58e-1)" "unprognostic (4.56e-3)" "unprognostic (3.92e-1)" "unprognostic (2.43e-1)" "unprognostic (3.11e-1)" "unprognostic (2.32e-3)" VSIG4 "CRIg, Z39IG" ENSG00000155659 "V-set and immunoglobulin domain containing 4" Q9Y279 X 66021738-66040125 "Plasma proteins, Predicted membrane proteins" "Complement alternate pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 156.3" "Cell type enhanced" "Detected in some" "cDC: 172.6;Hofbauer cells: 2052.5;Kupffer cells: 708.2;Macrophages: 452.7;monocytes: 314.5" "Cell type enriched" "Detected in some" 12 "central nervous system macrophage: 52.9" "Cancer enriched" "Detected in all" 4 "Glioblastoma Multiforme (TCGA): 177.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 26 "classical monocyte: 18.7;intermediate monocyte: 11.1;myeloid DC: 17.8" "Group enriched" "Detected in many" 30 "dendritic cells: 17.8;monocytes: 18.7" "Cancer enriched" "Detected in single" 7 "Leukemia: 2.7" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Thyroid gland - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA003903, CAB026000, HPA072756" Enhanced Uncertain "Nucleoli,Plasma membrane,Cytosol" NA NA 21000000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 86 "Plasma membrane, Cytosol" Nucleoli "CAB026000: , HPA003903: , HPA072756: " "unprognostic (2.26e-1)" "unprognostic (1.13e-2)" "unprognostic (2.33e-1)" "unprognostic (1.10e-1)" "unprognostic (6.84e-2)" "unprognostic (7.28e-3)" "unprognostic (8.25e-3)" "unprognostic (2.07e-1)" "unprognostic (9.73e-3)" "unprognostic (2.67e-1)" "potential prognostic unfavorable (6.15e-4)" "unprognostic (6.63e-2)" "unprognostic (2.09e-1)" "unprognostic (1.21e-2)" "unprognostic (1.35e-2)" "unprognostic (5.31e-2)" "unprognostic (7.19e-3)" "unprognostic (1.35e-2)" "unprognostic (4.33e-2)" "unprognostic (1.22e-3)" "unprognostic (2.48e-1)" "unprognostic (8.10e-2)" "unprognostic (3.45e-1)" "unprognostic (1.66e-1)" "unprognostic (2.19e-2)" "unprognostic (1.23e-1)" "unprognostic (1.01e-1)" "unprognostic (3.81e-2)" "unprognostic (1.50e-2)" "unprognostic (6.86e-2)" "unprognostic (1.18e-1)" VSIG8 ENSG00000243284 "V-set and immunoglobulin domain containing 8" P0DPA2 1 159854316-159862657 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 6.1;skin 1: 23.6" "Group enriched" "Detected in some" 4 "Choroid plexus epithelial cells: 1.3;Ependymal cells: 5.0" "Group enriched" "Detected in some" 4 "choroid plexus epithelial cell: 1.4;ependymal cell: 5.2" "Group enriched" "Detected in some" 13 "Bladder Urothelial Carcinoma (TCGA): 3.4;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 9.2;Head and Neck Squamous Cell Carcinoma (TCGA): 8.1;Uterine Corpus Endometrial Carcinoma (TCGA): 9.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 2.3;head and neck cancer: 1.5" "Kidney - Podocytes, Lung - Respiratory ciliated cells, Skin - Hair cortex cells, Skin - Inner root sheath cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA023219 Uncertain NA NA 340000 "Cluster 58: Skin - Keratinization" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 34: Ciliated cells - Cilia assembly & function" 2 "HPA023219: " "unprognostic (4.99e-3)" "unprognostic (4.97e-3)" "unprognostic (1.19e-1)" "unprognostic (1.47e-2)" "unprognostic (2.68e-1)" VSIR "B7-H5, B7H5, C10orf54, Dies1, GI24, PD-1H, SISP1, VISTA" ENSG00000107738 "V-set immunoregulatory receptor" Q9H7M9 10 71747556-71773520 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 76.9;lymphoid tissue: 87.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 409.1;Esophageal apical cells: 349.5;Extravillous trophoblasts: 423.5;Kupffer cells: 240.9;Microglia: 238.5;monocytes: 386.8;Neutrophil progenitors: 269.3;Neutrophils: 1249.4;Syncytiotrophoblasts: 843.7" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 282.0;endothelial cell: 163.7;leukocyte: 113.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1008.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Lung - Neutrophils_2, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" NA NA 150000 "Cluster 7: Non-specific - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 24 "unprognostic (1.80e-1)" "unprognostic (6.01e-2)" "unprognostic (1.54e-2)" "unprognostic (1.91e-1)" "unprognostic (2.07e-2)" "unprognostic (1.16e-1)" "unprognostic (6.81e-3)" "unprognostic (8.00e-2)" "unprognostic (1.30e-1)" "potential prognostic favorable (6.86e-5)" "unprognostic (5.00e-2)" "unprognostic (3.08e-3)" "unprognostic (1.46e-1)" "unprognostic (2.62e-1)" "unprognostic (1.32e-1)" "unprognostic (1.98e-2)" "unprognostic (8.82e-2)" "unprognostic (9.23e-3)" "unprognostic (3.02e-1)" "unprognostic (3.92e-1)" "unprognostic (1.99e-1)" "unprognostic (2.72e-2)" "unprognostic (2.59e-1)" "unprognostic (1.13e-1)" "unprognostic (1.20e-1)" "unprognostic (2.04e-1)" "potential prognostic unfavorable (5.12e-4)" "unprognostic (4.49e-2)" "unprognostic (1.27e-1)" VSNL1 "HLP3, HPCAL3, HUVISL1, VILIP, VILIP-1" ENSG00000163032 "Visinin like 1" P62760 2 17539126-17657018 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 17 "brain: 725.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 180.6;Brain excitatory neurons: 393.3;Brain inhibitory neurons: 219.4;Early primary spermatocytes: 92.4;Esophageal basal cells: 242.5;Esophageal suprabasal cells: 160.2;Ocular epithelial cells: 100.0;Other brain neurons: 151.0;Retinal amacrine cells: 108.8;Retinal ganglion cells: 85.0;Suprabasal keratinocytes: 134.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "cerebral cortex: 1751.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 112.8" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary gland basal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053808 Approved Cytosol NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 13 Cytosol "HPA053808: " "unprognostic (1.84e-1)" "unprognostic (9.90e-2)" "unprognostic (5.12e-2)" "unprognostic (1.77e-1)" "unprognostic (2.45e-1)" "unprognostic (1.90e-1)" "unprognostic (5.37e-3)" "unprognostic (1.22e-1)" "unprognostic (1.59e-2)" "unprognostic (2.07e-1)" "unprognostic (3.28e-2)" "unprognostic (9.13e-2)" "potential prognostic unfavorable (6.66e-5)" "unprognostic (1.75e-2)" "unprognostic (2.20e-1)" "unprognostic (1.52e-1)" "unprognostic (5.90e-2)" "unprognostic (2.51e-2)" "unprognostic (3.61e-1)" "unprognostic (2.87e-1)" "unprognostic (3.23e-1)" "unprognostic (2.66e-1)" "unprognostic (7.97e-2)" "unprognostic (2.73e-1)" "unprognostic (6.46e-2)" "unprognostic (2.22e-2)" "unprognostic (7.92e-2)" "unprognostic (1.59e-2)" VSTM1 UNQ3033 ENSG00000189068 "V-set and transmembrane domain containing 1" Q6UX27 19 54040825-54063953 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Immunity Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "bone marrow: 40.6" "Cell type enhanced" "Detected in some" "Early spermatids: 3.7;Gonadotrophs: 17.1;Late spermatids: 28.5;monocytes: 6.9;Neutrophil progenitors: 40.2;Neutrophils: 11.6;Oocytes: 4.6" "Cell type enhanced" "Detected in some" "hippocampal CA4: 2.4;leukocyte: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 16 "eosinophil: 129.6" "Lineage enriched" "Detected in many" 16 "granulocytes: 129.6" "Cancer enhanced" "Detected in single" "Leukemia: 1.2" "Adipose visceral - Neutrophils, Lung - Neutrophils_2, Pituitary gland - Gonadotropes, Spleen - Neutrophils_1" "Low region specificity" "Detected in all" HPA059365 Approved Vesicles "Secreted to blood" Cytokine NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" Vesicles "HPA059365: " "potential prognostic unfavorable (1.27e-4)" VSTM2A "MGC33530, VSTM2" ENSG00000170419 "V-set and transmembrane domain containing 2A" Q8TAG5 7 54542325-54571080 "Plasma proteins, Predicted secreted proteins" Differentiation "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 9.6;brain: 32.1;prostate: 9.1;retina: 13.2" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 31.9;Brain excitatory neurons: 9.4;Brain inhibitory neurons: 30.5;Oligodendrocyte progenitor cells: 9.4;Other brain neurons: 18.1;Pancreatic islet cells: 5.0;Retinal amacrine cells: 7.6;Retinal bipolar cells: 24.7" "Cell type enhanced" "Detected in many" "CGE interneuron: 64.0;eccentric medium spiny neuron: 63.8;LAMP5-LHX6 and Chandelier: 80.4" "Group enriched" "Detected in some" 5 "Breast Invasive Carcinoma (TCGA): 12.7;Glioblastoma Multiforme (TCGA): 9.3;Kidney Renal Papillary Cell Carcinoma (TCGA): 16.3;Prostate Adenocarcinoma (TCGA): 4.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Neuroblastoma: 7.7;prostate cancer: 4.5;thyroid cancer: 5.5" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted in other tissues" Other NA NA 110000 "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 1 "unprognostic (1.79e-1)" "unprognostic (7.49e-2)" "unprognostic (1.28e-1)" "unprognostic (2.36e-1)" "unprognostic (1.65e-2)" "unprognostic (3.18e-2)" "unprognostic (9.24e-2)" VSTM2B ENSG00000187135 "V-set and transmembrane domain containing 2B" A6NLU5 19 29525994-29564551 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 31.5" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 37.7;Brain inhibitory neurons: 54.9;Oligodendrocyte progenitor cells: 120.4;Oligodendrocytes: 135.6;Other brain neurons: 20.0;Retinal amacrine cells: 162.9;Retinal bipolar cells: 61.4;Retinal horizontal cells: 38.1" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in some" 4 "Glioblastoma Multiforme (TCGA): 6.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 1.5;Neuroblastoma: 1.0" "Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 53: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 109: Neurons - Neuronal signaling" "unprognostic (2.40e-1)" "potential prognostic favorable (3.82e-5)" "unprognostic (1.53e-1)" "unprognostic (2.70e-1)" "unprognostic (1.47e-1)" "potential prognostic unfavorable (2.75e-4)" VSTM2L "C20orf102, dJ1118M15.2" ENSG00000132821 "V-set and transmembrane domain containing 2 like" Q96N03 20 37903111-37945350 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 98.0;heart muscle: 78.7;lymphoid tissue: 28.5" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 74.5;Alveolar cells type 1: 43.5;Bergmann glia: 43.8;Brain inhibitory neurons: 72.6;Cholangiocytes: 54.1;Conjunctival goblet cells: 53.4;Fallopian tube ciliated cells: 90.0;Neuroendocrine cells: 51.6;Other brain neurons: 78.5;Pancreatic islet cells: 65.4;Respiratory ciliated cells: 219.3;Respiratory secretory cells: 46.8;Salivary duct cells: 119.5" "Cell type enhanced" "Detected in all" "midbrain-derived inhibitory: 216.7" "Group enriched" "Detected in all" 5 "Kidney Renal Papillary Cell Carcinoma (TCGA): 35.1;Lung Adenocarcinoma (TCGA): 60.8;Pancreatic Adenocarcinoma (TCGA): 51.8;Prostate Adenocarcinoma (TCGA): 107.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043832 Uncertain "Secreted - unknown location" "No annotated function" NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 109: Neurons - Neuronal signaling" 4 "HPA043832: " "unprognostic (4.10e-2)" "unprognostic (3.90e-2)" "unprognostic (1.58e-1)" "unprognostic (8.34e-2)" "unprognostic (4.62e-2)" "unprognostic (1.27e-1)" "unprognostic (2.41e-2)" "unprognostic (3.93e-2)" "unprognostic (1.35e-1)" "unprognostic (3.47e-2)" "unprognostic (1.23e-3)" "potential prognostic unfavorable (5.20e-5)" "potential prognostic favorable (2.39e-4)" "unprognostic (1.69e-2)" "unprognostic (7.82e-3)" "unprognostic (3.79e-2)" "potential prognostic unfavorable (9.43e-4)" "unprognostic (1.19e-2)" "unprognostic (2.28e-1)" "unprognostic (2.06e-3)" "unprognostic (4.22e-2)" "unprognostic (4.67e-2)" "unprognostic (3.95e-2)" "unprognostic (2.52e-1)" "unprognostic (1.42e-2)" "unprognostic (1.37e-1)" "unprognostic (1.55e-1)" "potential prognostic unfavorable (4.72e-4)" "unprognostic (1.54e-1)" "unprognostic (7.49e-2)" "unprognostic (1.75e-2)" VSTM4 "C10orf72, FLJ31737" ENSG00000165633 "V-set and transmembrane domain containing 4" Q8IW00 10 49014236-49115522 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 367.2;Alveolar cells type 2: 94.9;Early spermatids: 161.8;Granulosa cells: 103.0;Late spermatids: 203.8;Myosatellite cells: 73.1;Ovarian stromal cells: 68.7;Pericytes: 90.3;Proximal tubule cells: 81.0;Sertoli cells: 78.2;Vascular smooth muscle cells: 69.3" "Cell type enhanced" "Detected in all" "pericyte: 116.2;vascular associated smooth muscle cell: 111.2" "Cancer enriched" "Detected in all" 4 "Thyroid Carcinoma (TCGA): 44.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 8.2" "Lung - Fibroblasts_1, Minor Salivary Gland - Fibroblasts, Pituitary gland - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017279 Uncertain Approved Nucleoplasm,Vesicles "Secreted - unknown location" "No annotated function" NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 30: White matter - Myelination" "Cluster 15: Kidney cancer - Membrane components" "Cluster 18: Adrenal cortex cells - Steroidogensis" 9 "Nucleoplasm, Vesicles" "HPA017279: " "unprognostic (2.09e-1)" "unprognostic (1.89e-2)" "unprognostic (1.13e-1)" "unprognostic (2.28e-1)" "unprognostic (8.04e-2)" "unprognostic (1.27e-1)" "unprognostic (3.49e-2)" "unprognostic (4.85e-2)" "unprognostic (1.20e-2)" "potential prognostic favorable (3.07e-5)" "unprognostic (5.58e-3)" "unprognostic (6.17e-2)" "unprognostic (1.51e-1)" "unprognostic (2.26e-3)" "unprognostic (9.34e-2)" "unprognostic (1.11e-1)" "unprognostic (4.02e-2)" "unprognostic (1.41e-1)" "unprognostic (6.32e-2)" "unprognostic (1.40e-2)" "unprognostic (1.49e-1)" "unprognostic (1.94e-1)" "unprognostic (7.73e-3)" "unprognostic (1.62e-1)" "unprognostic (6.95e-2)" "unprognostic (6.92e-2)" "unprognostic (1.23e-2)" "unprognostic (1.29e-1)" "unprognostic (2.02e-1)" "unprognostic (1.04e-1)" VSTM5 "C11orf90, LOC387804" ENSG00000214376 "V-set and transmembrane domain containing 5" A8MXK1 11 93818232-93850618 "Predicted membrane proteins" "Developmental protein" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 4.5;placenta: 4.1" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 12.5;Brain inhibitory neurons: 12.9;Cytotrophoblasts: 76.4;Foveolar cells: 9.8;Gonadotrophs: 11.6;Migrating cytotrophoblasts: 18.3;Other brain neurons: 23.4;Podocytes: 10.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "prostate cancer: 4.2" "Kidney - Proximal tubular cells, Pituitary gland - Gonadotropes, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029525, HPA063591" Uncertain Uncertain "Endoplasmic reticulum" NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 1: Neurons - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 63: Cytotrophoblasts - Basic cellular functions" "Endoplasmic reticulum" "HPA029525: , HPA063591: " "unprognostic (3.45e-2)" "unprognostic (1.51e-1)" "unprognostic (8.89e-3)" "unprognostic (6.02e-2)" "unprognostic (1.75e-2)" "unprognostic (2.96e-2)" VSX1 "PPCD, PPCD1, PPD" ENSG00000100987 "Visual system homeobox 1" Q9NZR4 20 25070885-25082141 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Sensory transduction, Transcription, Transcription regulation, Vision" "Developmental protein, DNA-binding" "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 15.1;retina: 32.9" "Cell type enriched" "Detected in some" 16 "Retinal bipolar cells: 482.6" "Group enriched" "Detected in some" 4 "astrocyte: 14.8;Bergmann glia: 22.4;oligodendrocyte precursor cell: 35.4;upper rhombic lip: 19.5" "Not detected" "Not detected" "Region enriched" "Detected in all" 4 "cerebellum: 29.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA079607 Approved Nucleoli NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 35: Non-specific - DNA binding" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 2 Nucleoli "HPA079607: " "potential prognostic unfavorable (1.16e-4)" VSX2 "CHX10, HOX10, RET1" ENSG00000119614 "Visual system homeobox 2" P58304 14 74239449-74262738 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Sensory transduction, Transcription, Transcription regulation, Vision" "Activator, Developmental protein, DNA-binding, Repressor" "Cataract, Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 254 "retina: 68.4" "Group enriched" "Detected in some" 53 "Müller glia: 144.2;Retinal bipolar cells: 283.9" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 26 "Testicular Germ Cell Tumor (TCGA): 4.1" "Group enriched" "Detected in some" 7 "medulla oblongata: 2.5;midbrain: 1.0;pons: 3.5;spinal cord: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Group enriched" "Detected in some" 8 "midbrain: 1.3;pons and medulla: 1.7" "Region enhanced" "Detected in single" "pons: 2.4" HPA003436 Enhanced NA NA "Cluster 42: Retina - Visual perception" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 55: Lymphoma - Immune response" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 20 "HPA003436: " "unprognostic (1.06e-1)" VTA1 "C6orf55, HSPC228, My012" ENSG00000009844 "Vesicle trafficking 1" Q9NP79 6 142147162-142224685 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030968, HPA030969" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA 350000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" 33 "Nucleoplasm, Vesicles, Cytosol" "HPA030968: , HPA030969: " "unprognostic (1.91e-3)" "potential prognostic unfavorable (5.37e-5)" "unprognostic (1.08e-2)" "unprognostic (3.46e-3)" "unprognostic (4.42e-3)" "unprognostic (1.23e-1)" "unprognostic (1.17e-2)" "unprognostic (1.05e-1)" "unprognostic (4.29e-2)" "unprognostic (5.71e-3)" "potential prognostic favorable (1.86e-5)" "unprognostic (5.95e-2)" "unprognostic (5.16e-3)" "potential prognostic unfavorable (3.60e-5)" "unprognostic (2.02e-3)" "unprognostic (1.26e-3)" "unprognostic (2.42e-2)" "unprognostic (5.06e-2)" "unprognostic (2.33e-1)" "potential prognostic unfavorable (2.24e-4)" "unprognostic (2.14e-2)" "unprognostic (4.41e-3)" "unprognostic (1.40e-2)" "unprognostic (1.97e-1)" "unprognostic (1.08e-2)" "unprognostic (4.65e-1)" "unprognostic (2.15e-1)" "unprognostic (1.55e-1)" "unprognostic (2.71e-1)" "unprognostic (9.95e-2)" "unprognostic (2.24e-1)" VTCN1 "B7-H4, B7H4, B7S1, B7x, FLJ22418" ENSG00000134258 "V-set domain containing T cell activation inhibitor 1" Q7Z7D3 1 117143587-117210960 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 94.8;fallopian tube: 30.5;pancreas: 28.4" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 152.7;Breast secretory cells: 100.6;Endometrial luminal cells: 239.7;Fallopian secretory cells: 103.4;Lacrimal acinar cells: 76.1;Pancreatic duct cells: 118.8;Prostatic club cells: 117.7;Respiratory deuterosomal cells: 101.6;Respiratory secretory cells: 98.6;Salivary ionocytes: 85.4;Submucosal glandular cells: 62.9" "Cell type enhanced" "Detected in some" "committed oligodendrocyte precursor: 1.8" "Group enriched" "Detected in many" 5 "Breast Invasive Carcinoma (TCGA): 100.1;Ovary Serous Cystadenocarcinoma (TCGA): 78.0;Uterine Corpus Endometrial Carcinoma (TCGA): 88.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 51.0;ovarian cancer: 27.5;testis cancer: 27.6" "Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Prostate - Urothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA054200 Approved Approved "Plasma membrane,Cell Junctions,Focal adhesion sites" No NA "Cluster 55: Breast - Lactation" "Cluster 27: Breast cancer - Unknown function" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 6 "Plasma membrane" "Cell Junctions, Focal adhesion sites" "HPA054200: " "unprognostic (3.83e-2)" "unprognostic (3.49e-1)" "unprognostic (3.62e-1)" "unprognostic (9.13e-3)" "unprognostic (2.80e-1)" "unprognostic (2.22e-1)" "unprognostic (1.26e-1)" "unprognostic (1.33e-1)" "unprognostic (2.73e-1)" "unprognostic (1.47e-1)" "unprognostic (9.34e-2)" "unprognostic (5.45e-2)" "unprognostic (1.97e-1)" "unprognostic (2.65e-2)" "unprognostic (3.02e-1)" "unprognostic (3.18e-2)" "unprognostic (9.04e-2)" "unprognostic (6.31e-2)" "unprognostic (1.87e-1)" "unprognostic (2.77e-2)" "unprognostic (2.28e-1)" "potential prognostic unfavorable (2.25e-4)" VTI1A "MVti1, Vti1-rp2" ENSG00000151532 "Vesicle transport through interaction with t-SNAREs 1A" Q96AJ9 10 112446998-112818744 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Podocytes: 3174.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054108 Supported Approved "Golgi apparatus,Vesicles" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 57: Podocytes - Glomerular filtration" 42 "Golgi apparatus, Vesicles" "HPA054108: " "unprognostic (5.89e-2)" "unprognostic (4.79e-2)" "unprognostic (1.30e-2)" "unprognostic (5.77e-2)" "unprognostic (2.19e-1)" "unprognostic (1.28e-1)" "unprognostic (2.80e-1)" "unprognostic (2.12e-3)" "unprognostic (2.55e-1)" "unprognostic (1.50e-3)" "potential prognostic favorable (2.35e-5)" "unprognostic (4.91e-2)" "unprognostic (9.10e-2)" "unprognostic (1.69e-3)" "unprognostic (1.83e-1)" "unprognostic (1.25e-1)" "unprognostic (1.44e-2)" "unprognostic (7.15e-2)" "unprognostic (1.32e-1)" "unprognostic (4.81e-3)" "unprognostic (8.62e-3)" "unprognostic (9.52e-2)" "potential prognostic unfavorable (4.44e-4)" "unprognostic (1.21e-1)" "unprognostic (1.08e-1)" "unprognostic (3.23e-2)" "unprognostic (3.15e-1)" "unprognostic (4.05e-3)" "unprognostic (3.30e-2)" "unprognostic (1.16e-2)" "unprognostic (3.73e-2)" VTI1B VTI2 ENSG00000100568 "Vesicle transport through interaction with t-SNAREs 1B" Q9UEU0 14 67647085-67674820 "Essential proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 419.3;Late spermatids: 730.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044121, HPA048150, HPA060118" Approved Enhanced "Golgi apparatus,Vesicles" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 14: Neurons - Synaptic function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 54 "Golgi apparatus, Vesicles" "HPA044121: , HPA048150: , HPA060118: " "unprognostic (2.51e-1)" "unprognostic (1.78e-1)" "unprognostic (4.55e-1)" "unprognostic (2.65e-1)" "unprognostic (1.89e-1)" "unprognostic (4.16e-2)" "unprognostic (1.02e-1)" "unprognostic (1.79e-1)" "unprognostic (1.41e-3)" "potential prognostic unfavorable (1.88e-4)" "unprognostic (1.47e-3)" "unprognostic (1.97e-3)" "potential prognostic favorable (2.72e-6)" "unprognostic (1.27e-2)" "unprognostic (1.29e-2)" "unprognostic (2.25e-3)" "unprognostic (1.65e-1)" "unprognostic (8.25e-2)" "unprognostic (1.54e-1)" "unprognostic (7.82e-2)" "unprognostic (1.21e-2)" "unprognostic (1.97e-2)" "unprognostic (1.09e-1)" "unprognostic (5.56e-2)" "unprognostic (2.69e-2)" "unprognostic (7.44e-2)" "unprognostic (2.00e-1)" "unprognostic (5.42e-3)" "unprognostic (1.27e-1)" "unprognostic (1.58e-1)" "unprognostic (1.41e-1)" VTN VN ENSG00000109072 Vitronectin P04004 17 28367284-28373091 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins, Transporters" "Cell adhesion" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 46 "liver: 5644.8" "Group enriched" "Detected in some" 60 "Cholangiocytes: 898.8;Hepatocytes: 2941.5" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in many" 62 "Liver Hepatocellular Carcinoma (TCGA): 4796.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 132.3" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB016695, CAB016765, HPA060933, HPA068011" Supported Supported "Endoplasmic reticulum,Vesicles" "Secreted to blood" "Cell adhesion" NA NA 606000000000 46000000000 "Cluster 53: Liver - Plasma proteins" "Cluster 15: Non-specific - Transcription" "Cluster 18: Liver cancer - Metabolism" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 21 "Endoplasmic reticulum, Vesicles" "CAB016695: , CAB016765: , HPA060933: , HPA068011: " "unprognostic (1.27e-1)" "unprognostic (4.30e-2)" "unprognostic (2.25e-1)" "unprognostic (3.08e-2)" "unprognostic (6.31e-2)" "unprognostic (3.43e-2)" "potential prognostic unfavorable (4.22e-5)" "unprognostic (8.05e-2)" "potential prognostic unfavorable (1.00e-4)" "validated prognostic favorable (3.70e-4)" "validated prognostic favorable (8.61e-5)" "unprognostic (1.78e-1)" "unprognostic (1.49e-1)" "potential prognostic unfavorable (1.07e-5)" "unprognostic (1.49e-1)" "unprognostic (6.85e-3)" "unprognostic (5.96e-3)" "unprognostic (5.46e-2)" "unprognostic (3.39e-1)" "unprognostic (1.69e-3)" "unprognostic (2.47e-1)" VWA1 "FLJ22215, VWA-1, WARP" ENSG00000179403 "Von Willebrand factor A domain containing 1" Q6PCB0 1 1434861-1442882 "Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 192.1" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 145.5;Cytotrophoblasts: 334.0;Migrating cytotrophoblasts: 231.8;Schwann cells: 375.1;Smooth muscle cells: 133.1;Syncytiotrophoblasts: 314.9;Vascular endothelial cells: 114.4" "Cell type enhanced" "Detected in many" "endothelial cell: 74.1;fibroblast: 63.1;oligodendrocyte: 129.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 115.4" "Adrenal gland - Endothelial cells, Kidney - Endothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Endothelial cells, Prostate - Smooth muscle cells, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" "No annotated function" NA NA 320000 "Cluster 74: Non-specific - Signal transduction" "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 1 "unprognostic (3.47e-1)" "unprognostic (2.09e-1)" "unprognostic (1.77e-3)" "unprognostic (2.31e-3)" "unprognostic (1.99e-2)" "unprognostic (6.86e-2)" "potential prognostic unfavorable (9.79e-4)" "unprognostic (8.00e-2)" "unprognostic (9.26e-2)" "unprognostic (9.80e-2)" "validated prognostic favorable (1.19e-8)" "validated prognostic favorable (9.55e-4)" "unprognostic (1.74e-1)" "unprognostic (1.70e-2)" "unprognostic (1.73e-1)" "unprognostic (2.91e-2)" "unprognostic (4.94e-2)" "unprognostic (2.18e-2)" "unprognostic (2.39e-1)" "unprognostic (4.24e-2)" "unprognostic (4.85e-2)" "unprognostic (9.40e-2)" "unprognostic (5.48e-1)" "unprognostic (2.93e-2)" "unprognostic (1.01e-3)" "unprognostic (1.26e-1)" "unprognostic (2.65e-1)" "unprognostic (1.98e-1)" "unprognostic (1.74e-1)" "unprognostic (3.26e-1)" "unprognostic (1.08e-1)" VWA2 "AMACO, CCSP-2, FLJ16213, FLJ45857, NET42" ENSG00000165816 "Von Willebrand factor A domain containing 2" Q5GFL6 10 114239254-114294489 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 8.1" "Cell type enhanced" "Detected in many" "Early spermatids: 32.9;Epididymal basal cells: 51.1;Epididymal efferent duct absorptive cells: 35.4;Epididymal efferent duct ciliated cells: 96.5;Fallopian tube ciliated cells: 33.7;Gastric chief cells: 53.5;Late spermatids: 43.1;Medullary thymic epithelial cells: 45.6;Mucous neck cells: 73.6;Respiratory basal cells: 36.5;Respiratory ciliated cells: 31.4;Respiratory deuterosomal cells: 41.5;Respiratory secretory cells: 36.5" "Group enriched" "Detected in some" 7 "deep-layer corticothalamic and 6b: 32.0;deep-layer near-projecting: 32.3;endothelial cell: 105.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 10.1;Gastric cancer: 6.4" "Breast - Breast glandular cells, Colon - Enteric glia cells, Lung - Alveolar cells type 2, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA037847 Uncertain "Secreted to extracellular matrix" "No annotated function" NA NA "Cluster 82: Salivary gland - Secretion" "Cluster 6: Non-specific - Immune response" "Cluster 32: Non-specific - Cell proliferation" "Cluster 104: Brain endothelial cells - Blood brain barrier" 1 "HPA037847: " "unprognostic (1.21e-1)" "unprognostic (7.06e-2)" "unprognostic (4.42e-1)" "unprognostic (1.24e-1)" "unprognostic (8.53e-2)" "unprognostic (1.12e-1)" "unprognostic (3.70e-2)" "unprognostic (6.29e-2)" "unprognostic (2.27e-3)" "unprognostic (2.04e-1)" "unprognostic (4.27e-3)" "unprognostic (7.54e-2)" "unprognostic (5.28e-2)" "unprognostic (3.14e-1)" "unprognostic (4.75e-3)" "unprognostic (3.22e-3)" "unprognostic (2.31e-1)" "unprognostic (8.28e-2)" "unprognostic (7.81e-3)" "unprognostic (4.28e-2)" "unprognostic (1.23e-1)" "unprognostic (2.31e-2)" VWA3A "FLJ40941, FLJ46765" ENSG00000175267 "Von Willebrand factor A domain containing 3A" A6NCI4 16 22092538-22156964 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 53.8;fallopian tube: 30.8;pituitary gland: 16.2" "Group enriched" "Detected in some" 13 "Choroid plexus epithelial cells: 300.3;Ependymal cells: 865.4" "Cell type enriched" "Detected in all" 4 "ependymal cell: 911.9" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 6.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Bile duct cancer: 2.5" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA041696, HPA042044" Uncertain "Secreted in other tissues" "No annotated function" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" "HPA041696: , HPA042044: " "unprognostic (7.78e-2)" "unprognostic (1.20e-1)" "unprognostic (1.12e-1)" "unprognostic (6.14e-2)" "unprognostic (5.89e-3)" "unprognostic (6.89e-2)" "unprognostic (9.23e-2)" "unprognostic (1.00e-1)" "unprognostic (6.99e-3)" "unprognostic (9.13e-2)" VWA3B "DKFZp686F2227, MGC26733" ENSG00000168658 "Von Willebrand factor A domain containing 3B" Q502W6 2 98087116-98313299 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Intellectual disability, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "choroid plexus: 8.8;fallopian tube: 20.9;testis: 28.8" "Cell type enhanced" "Detected in many" "Early spermatids: 596.2;Endometrial ciliated cells: 181.6;Ependymal cells: 361.7;Fallopian tube ciliated cells: 253.7;Late primary spermatocytes: 230.0;Late spermatids: 1801.3;Respiratory ciliated cells: 643.0" "Cell type enriched" "Detected in many" 5 "ependymal cell: 412.1" "Cancer enhanced" "Detected in some" "Lung Adenocarcinoma (TCGA): 1.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in many" 4 "hippocampal formation: 7.1" "Low region specificity" "Detected in many" "HPA036700, HPA036701" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 24: Non-specific - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" "Nucleoplasm, Cytosol" "HPA036700: , HPA036701: " "unprognostic (1.71e-1)" "unprognostic (3.67e-3)" "unprognostic (2.79e-3)" "unprognostic (6.28e-2)" "unprognostic (3.29e-1)" VWA5A "BCSC-1, LOH11CR2A" ENSG00000110002 "Von Willebrand factor A domain containing 5A" O00534 11 124115404-124147721 "Predicted intracellular proteins" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "Mast cells: 500.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 58.2" "Lineage enriched" "Detected in all" 5 "granulocytes: 58.2" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Region enhanced" "Detected in many" "hypothalamus: 166.8" "Low region specificity" "Detected in all" "HPA037813, HPA037814, HPA061500" Uncertain Enhanced Nucleoplasm,Nucleoli NA NA 4000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 77: Intestine - Digestion" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 58: Mast cells - Allergic inflammatory responses" 3 Nucleoplasm Nucleoli "HPA037813: , HPA037814: , HPA061500: " "unprognostic (6.10e-2)" "unprognostic (2.27e-1)" "unprognostic (8.35e-2)" "unprognostic (1.43e-1)" "unprognostic (5.12e-2)" "unprognostic (4.28e-2)" "unprognostic (6.16e-3)" "unprognostic (5.71e-2)" "unprognostic (2.42e-1)" "unprognostic (1.42e-1)" "unprognostic (2.62e-2)" "unprognostic (1.74e-2)" "potential prognostic favorable (7.50e-5)" "unprognostic (6.62e-2)" "unprognostic (1.96e-1)" "unprognostic (2.38e-1)" "unprognostic (9.81e-2)" "unprognostic (7.80e-2)" "unprognostic (1.64e-1)" "unprognostic (2.25e-1)" "unprognostic (2.40e-1)" "unprognostic (4.61e-2)" "unprognostic (5.74e-2)" "unprognostic (5.31e-2)" "unprognostic (5.41e-3)" "unprognostic (3.84e-1)" "unprognostic (1.87e-1)" "unprognostic (7.09e-2)" "unprognostic (1.19e-1)" "unprognostic (2.37e-1)" "unprognostic (1.21e-1)" VWA5B1 FLJ32784 ENSG00000158816 "Von Willebrand factor A domain containing 5B1" Q5TIE3 1 20290875-20359518 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 13.2;pituitary gland: 11.1" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 262.6;Ependymal cells: 223.0;Epididymal clear cells: 281.7;Gonadotrophs: 61.0;Papillary tip epithelial cells: 63.7;Renal collecting duct intercalated cells: 189.2;Renal collecting duct principal cells: 52.7;Somatotrophs: 295.3;Thyrotrophs: 50.4" "Group enriched" "Detected in many" 13 "choroid plexus epithelial cell: 173.2;ependymal cell: 221.9" "Cancer enriched" "Detected in single" 8 "Kidney Chromophobe (TCGA): 2.4" "Region enhanced" "Detected in many" "choroid plexus: 47.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adrenal gland - Adrenal medulla cells, Kidney - Intercalated cells, Lung - Fibroblasts_1, Pituitary gland - Somatotropes, Skin - Eccrine sweat gland cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA027496, HPA028405, HPA064829" Enhanced Approved "Plasma membrane,Mitochondria,Cytosol" "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 44: Non-specific - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 34: Ciliated cells - Cilia assembly & function" Mitochondria "Plasma membrane, Cytosol" "HPA027496: , HPA028405: , HPA064829: " "unprognostic (1.57e-1)" "unprognostic (3.43e-1)" VWA5B2 "DKFZp761K032, LOC90113" ENSG00000145198 "Von Willebrand factor A domain containing 5B2" Q8N398 3 184229585-184242329 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "adrenal gland: 40.1;brain: 17.2" "Cell type enhanced" "Detected in some" "Adrenal cortex cells: 28.5;Adrenal medulla cells: 255.3;Brain excitatory neurons: 43.7;Brain inhibitory neurons: 29.1;Gonadotrophs: 23.0;Neuroendocrine cells: 85.8;Other brain neurons: 21.9;Pancreatic islet cells: 65.6;Retinal ganglion cells: 38.6" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Pancreatic Adenocarcinoma (TCGA): 3.0;Stomach Adenocarcinoma (TCGA): 2.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 5.3;lung cancer: 5.1" "Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Pancreas - Beta cells, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 27.3" "HPA036823, HPA036824, HPA061412" Enhanced Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" 7 "Golgi apparatus" Nucleoplasm "HPA036823: , HPA036824: , HPA061412: " "unprognostic (7.69e-2)" "unprognostic (2.28e-3)" "unprognostic (8.60e-2)" VWA7 "C6orf27, G7c, NG37" ENSG00000204396 "Von Willebrand factor A domain containing 7" Q9Y334 6 31765590-31777328 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 20.0" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 1.5;Distal convoluted tubule cells: 2.0;Fallopian tube ciliated cells: 3.1;Loop of henle epithelial cells: 2.1;Other brain neurons: 1.4;Papillary tip epithelial cells: 1.5;Podocytes: 2.3;Proximal tubule cells: 2.2;Renal collecting duct intercalated cells: 1.1;Renal collecting duct principal cells: 2.4;Renal connecting tubule cells: 2.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Pituitary gland - Lactotropes, Skeletal muscle - Skeletal myocytes, Stomach - Gastric mucous cells" "Group enriched" "Detected in some" 5 "cerebellum: 7.0;pons and medulla: 3.9" "Low region specificity" "Detected in many" "HPA046954, HPA054262" Approved Approved "Plasma membrane,Cytosol" "Secreted - unknown location" "No annotated function" NA NA 6500 "Cluster 20: Pituitary gland - Hormone signaling" "Cluster 24: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" "Plasma membrane, Cytosol" "HPA046954: , HPA054262: " "unprognostic (8.31e-2)" "unprognostic (4.41e-2)" "unprognostic (1.15e-2)" "unprognostic (1.07e-1)" "unprognostic (3.06e-2)" "unprognostic (6.69e-2)" "unprognostic (2.76e-3)" "potential prognostic unfavorable (7.01e-5)" "unprognostic (1.48e-1)" "unprognostic (1.83e-1)" "unprognostic (1.54e-2)" VWA8 "KIAA0564, P7BP2" ENSG00000102763 "Von Willebrand factor A domain containing 8" A3KMH1 13 41566835-41961120 "Predicted intracellular proteins" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Choroid plexus epithelial cells: 761.2;Myonuclei: 1172.2;Rod photoreceptor cells: 867.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039075, HPA045478" Uncertain Approved "Vesicles,Lipid droplets" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 19: Non-specific - Unknown function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 20 "Vesicles, Lipid droplets" "HPA039075: , HPA045478: " "unprognostic (4.44e-2)" "unprognostic (2.00e-2)" "unprognostic (1.86e-1)" "unprognostic (7.29e-2)" "unprognostic (2.49e-1)" "unprognostic (2.11e-2)" "unprognostic (2.77e-1)" "unprognostic (6.38e-2)" "unprognostic (9.45e-2)" "potential prognostic favorable (3.84e-11)" "unprognostic (1.77e-3)" "unprognostic (4.73e-3)" "unprognostic (1.81e-3)" "unprognostic (3.53e-2)" "unprognostic (2.98e-2)" "unprognostic (1.20e-1)" "unprognostic (2.21e-1)" "potential prognostic unfavorable (3.58e-4)" "unprognostic (2.66e-2)" "unprognostic (7.61e-2)" "unprognostic (1.11e-2)" "unprognostic (2.41e-1)" "unprognostic (1.84e-1)" "unprognostic (8.43e-2)" "unprognostic (2.60e-1)" "unprognostic (2.98e-1)" "unprognostic (1.10e-1)" "unprognostic (1.25e-1)" "unprognostic (1.45e-2)" VWC2 "PSST739, UNQ739" ENSG00000188730 "Von Willebrand factor C domain containing 2" Q2TAL6 7 49773638-49921950 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 10.3;heart muscle: 4.6;ovary: 3.7" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 147.8;Brain inhibitory neurons: 134.2;Cardiomyocytes: 137.5;Endometrial stromal cells: 83.5;Granulosa cells: 279.8;Oligodendrocyte progenitor cells: 257.9;Other brain neurons: 90.8;Ovarian stromal cells: 134.0;Retinal amacrine cells: 133.4;Retinal bipolar cells: 413.0;Retinal ganglion cells: 517.6;Rod photoreceptor cells: 270.0" "Cell type enhanced" "Detected in many" "LAMP5-LHX6 and Chandelier: 634.7;upper rhombic lip: 447.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Skin - Langerhans cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055243 Approved "Secreted to extracellular matrix" "No annotated function" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 15: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 53 "HPA055243: " "unprognostic (1.85e-2)" VWC2L ENSG00000174453 "Von Willebrand factor C domain containing 2 like" B2RUY7 2 214411054-214578976 "Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 2.4;retina: 1.3" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 59.4;Brain inhibitory neurons: 69.1;Ependymal cells: 48.6;Epicardial cells: 150.1;Lactotrophs: 91.1;Myonuclei: 38.5;Other brain neurons: 68.4;Pancreatic islet cells: 40.9;Retinal amacrine cells: 51.1;Somatotrophs: 68.7;Thyrotrophs: 123.4" "Cell type enhanced" "Detected in all" "deep-layer near-projecting: 458.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pituitary gland - Lactotropes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA044815, HPA059414" Uncertain "Secreted - unknown location" "Developmental protein" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 109: Neurons - Neuronal signaling" 20 "HPA044815: , HPA059414: " "potential prognostic favorable (8.83e-5)" VWCE "FLJ32009, URG11, VWC1" ENSG00000167992 "Von Willebrand factor C and EGF domains" Q96DN2 11 61258286-61295316 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 16.3;ovary: 9.1" "Cell type enhanced" "Detected in many" "Astrocytes: 22.9;Cone photoreceptor cells: 47.6;Ependymal cells: 45.6;Erythrocyte progenitors: 40.4;Hepatocytes: 25.8;Medullary thymic epithelial cells: 28.8;Rod photoreceptor cells: 47.6" "Cell type enhanced" "Detected in many" "ependymal cell: 39.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 6.1" "Colon - Endothelial cells, Lung - Fibroblasts_2, Prostate - Urothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA040401, HPA043921" Uncertain Supported Nucleoplasm,Vesicles,Cytosol "Secreted - unknown location" "No annotated function" NA NA 110000 "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 18: Liver cancer - Metabolism" "Cluster 82: Dendritic cells - Antigen presentation" 5 Nucleoplasm "Vesicles, Cytosol" "HPA040401: , HPA043921: " "unprognostic (1.31e-1)" "unprognostic (2.74e-2)" "potential prognostic favorable (2.93e-4)" "potential prognostic favorable (5.96e-4)" "unprognostic (2.27e-1)" "unprognostic (3.31e-3)" "unprognostic (1.02e-1)" "unprognostic (9.43e-2)" "unprognostic (3.08e-2)" "unprognostic (5.04e-2)" "unprognostic (6.44e-3)" "unprognostic (2.47e-1)" "unprognostic (2.73e-1)" "unprognostic (2.60e-1)" VWDE FLJ14712 ENSG00000146530 "Von Willebrand factor D and EGF domains" Q8N2E2 7 12330885-12403941 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 3.8;salivary gland: 2.8;thyroid gland: 2.9" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 42.5;Corticotrophs: 89.4;Erythrocyte progenitors: 52.7;Gonadotrophs: 59.8;Lacrimal acinar cells: 71.6;Lactotrophs: 179.7;Megakaryocyte-Erythroid progenitors: 72.4;Somatotrophs: 256.8;Thyrotrophs: 109.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 11.6" "Pancreas - Alpha cells, Pancreas - Beta cells" "Low region specificity" "Detected in many" "HPA026619, HPA036044, HPA036045" Uncertain Approved Cytosol "Secreted - unknown location" "No annotated function" NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 28 Cytosol "HPA026619: , HPA036044: , HPA036045: " "unprognostic (9.39e-2)" "unprognostic (1.29e-1)" "unprognostic (1.95e-3)" "unprognostic (1.28e-1)" "unprognostic (7.74e-2)" "unprognostic (7.97e-2)" "unprognostic (2.88e-2)" "potential prognostic unfavorable (1.42e-5)" "unprognostic (3.60e-1)" VWF F8VWF ENSG00000110799 "Von Willebrand factor" P04275 12 5948877-6124770 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Cell adhesion, Hemostasis" "Cancer-related genes, Disease variant, FDA approved drug targets, von Willebrand disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Lymphatic endothelial cells: 414.1;Vascular endothelial cells: 1630.6" "Cell type enriched" "Detected in many" 13 "endothelial cell: 1181.2" "Cancer enriched" "Detected in all" 4 "Kidney Renal Clear Cell Carcinoma (TCGA): 196.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Minor Salivary Gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001694, HPA001815, HPA002082, CAB072874, CAB072875" Supported "Secreted to blood" "Blood coagulation" NA NA 28300000000 5700000000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 12 "CAB001694: , CAB072874: , CAB072875: , HPA001815: , HPA002082: " "unprognostic (2.57e-1)" "unprognostic (3.86e-1)" "unprognostic (1.44e-3)" "unprognostic (2.94e-1)" "unprognostic (6.69e-2)" "unprognostic (7.81e-3)" "unprognostic (1.24e-1)" "unprognostic (5.14e-2)" "unprognostic (2.63e-2)" "unprognostic (4.13e-2)" "potential prognostic favorable (5.48e-9)" "unprognostic (1.34e-3)" "unprognostic (2.44e-2)" "unprognostic (1.31e-1)" "unprognostic (1.97e-2)" "unprognostic (4.36e-2)" "unprognostic (1.18e-1)" "unprognostic (2.13e-2)" "unprognostic (6.69e-2)" "unprognostic (7.28e-2)" "unprognostic (3.62e-2)" "unprognostic (2.23e-1)" "unprognostic (7.57e-2)" "unprognostic (1.86e-1)" "unprognostic (5.86e-2)" "unprognostic (2.59e-1)" "unprognostic (7.36e-2)" "potential prognostic unfavorable (1.93e-4)" "unprognostic (1.09e-1)" "unprognostic (9.44e-2)" "unprognostic (1.42e-3)" VXN "C8orf46, MGC33510" ENSG00000169085 Vexin Q8TAG6 8 66492326-66518524 "Predicted intracellular proteins" Neurogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "brain: 113.4" "Cell type enhanced" "Detected in some" "Astrocytes: 14.3;Bergmann glia: 7.7;Brain excitatory neurons: 24.8;Brain inhibitory neurons: 9.2;Choroid plexus epithelial cells: 6.2;Distal convoluted tubule cells: 6.8;Loop of henle epithelial cells: 13.4;Oligodendrocyte progenitor cells: 40.0;Oligodendrocytes: 37.1;Podocytes: 9.3;Proximal tubule cells: 15.0;Renal connecting tubule cells: 7.0" "Cell type enhanced" "Detected in many" "hippocampal CA1-3: 79.6" "Cancer enriched" "Detected in some" 5 "Glioblastoma Multiforme (TCGA): 50.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 8.8;skin cancer: 5.9" "Group enriched" "Detected in all" 8 "amygdala: 159.8;basal ganglia: 78.9;cerebral cortex: 298.3;hippocampal formation: 219.4;white matter: 199.6" "Low region specificity" "Detected in all" HPA075134 Approved "Nuclear speckles" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Neurons - Synaptic function & neurogenesis" 5 "Nuclear speckles" "HPA075134: " "unprognostic (1.44e-1)" "unprognostic (1.02e-1)" "unprognostic (1.45e-2)" "unprognostic (8.06e-2)" "unprognostic (3.80e-2)" "unprognostic (2.26e-1)" "unprognostic (1.53e-1)" "unprognostic (2.99e-1)" WAC "BM-016, FLJ31290, MGC10753, PRO1741, Wwp4" ENSG00000095787 "WW domain containing adaptor with coiled-coil" Q9BTA9 10 28532493-28623112 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 1114.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036528, HPA042609, HPA074604" Approved Enhanced Nucleoplasm,Centrosome NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 25 Nucleoplasm Centrosome "HPA036528: , HPA042609: , HPA074604: " "unprognostic (2.41e-2)" "unprognostic (5.16e-2)" "unprognostic (1.27e-1)" "unprognostic (2.53e-3)" "unprognostic (1.09e-1)" "unprognostic (1.86e-3)" "unprognostic (4.67e-2)" "potential prognostic favorable (1.80e-5)" "unprognostic (1.42e-1)" "unprognostic (2.06e-2)" "potential prognostic favorable (8.25e-7)" "unprognostic (1.84e-3)" "unprognostic (2.94e-1)" "unprognostic (7.01e-2)" "potential prognostic unfavorable (8.92e-4)" "unprognostic (9.05e-2)" "unprognostic (4.09e-2)" "unprognostic (9.36e-3)" "unprognostic (4.38e-2)" "unprognostic (1.30e-2)" "unprognostic (5.04e-3)" "unprognostic (1.26e-2)" "unprognostic (2.52e-2)" "unprognostic (1.42e-1)" "unprognostic (5.50e-2)" "unprognostic (2.22e-1)" "unprognostic (1.05e-1)" "unprognostic (3.29e-2)" "unprognostic (7.76e-2)" "unprognostic (8.05e-3)" "unprognostic (5.12e-1)" WAPL "FOE, KIAA0261, WAPAL" ENSG00000062650 "WAPL cohesin release factor" Q7Z5K2 10 86435256-86521792 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Host-virus interaction, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037874, HPA037875, HPA066141" Enhanced Supported Nucleoplasm NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 39: Testis - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 17: Non-specific - RNA processing" 42 Nucleoplasm "HPA037874: , HPA037875: , HPA066141: " "unprognostic (8.08e-2)" "unprognostic (2.54e-2)" "unprognostic (6.31e-2)" "unprognostic (5.44e-2)" "unprognostic (1.51e-1)" "unprognostic (1.04e-1)" "potential prognostic favorable (3.46e-4)" "unprognostic (3.61e-1)" "unprognostic (9.56e-3)" "potential prognostic favorable (3.30e-6)" "unprognostic (2.16e-2)" "unprognostic (6.11e-2)" "unprognostic (3.70e-2)" "unprognostic (5.43e-2)" "unprognostic (4.26e-2)" "unprognostic (1.05e-1)" "unprognostic (2.38e-1)" "unprognostic (2.77e-2)" "unprognostic (1.09e-2)" "unprognostic (1.48e-2)" "unprognostic (8.77e-2)" "unprognostic (6.34e-2)" "unprognostic (2.73e-2)" "unprognostic (1.87e-1)" "unprognostic (2.00e-1)" "unprognostic (2.26e-1)" "unprognostic (3.14e-1)" "unprognostic (1.39e-2)" "unprognostic (1.63e-1)" WARS1 "IFI53, IFP53, WARS" ENSG00000140105 "Tryptophanyl-tRNA synthetase 1" P23381 14 100333790-100376805 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Angiogenesis, Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Intellectual disability, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 304.7" "Cell type enhanced" "Detected in all" "Endometrial luminal cells: 168.6;Late primary spermatocytes: 173.1;Late spermatids: 168.6;monocytes: 301.0;Pituicytes/FSCs: 166.5;Schwann cells: 282.7;Vascular endothelial cells: 232.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "intermediate monocyte: 1347.2;non-classical monocyte: 1617.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005573, HPA018944" Enhanced Enhanced Cytosol No No 21000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 13: Non-specific - Mixed function" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 9 Cytosol "HPA005573: , HPA018944: " "unprognostic (9.57e-2)" "unprognostic (2.74e-2)" "unprognostic (1.92e-1)" "unprognostic (9.60e-2)" "unprognostic (8.42e-2)" "unprognostic (8.00e-2)" "unprognostic (1.88e-1)" "unprognostic (4.79e-2)" "unprognostic (5.50e-2)" "unprognostic (5.41e-3)" "unprognostic (6.04e-2)" "unprognostic (2.95e-2)" "unprognostic (3.60e-3)" "unprognostic (1.13e-2)" "unprognostic (6.07e-2)" "unprognostic (1.27e-1)" "unprognostic (9.88e-2)" "unprognostic (1.57e-2)" "unprognostic (4.36e-1)" "unprognostic (2.31e-2)" "unprognostic (6.14e-3)" "unprognostic (1.86e-1)" "unprognostic (3.10e-1)" "unprognostic (1.49e-2)" "unprognostic (8.04e-2)" "unprognostic (3.59e-2)" "unprognostic (2.25e-2)" "unprognostic (9.89e-2)" "unprognostic (1.42e-2)" WARS2 mtTrpRS ENSG00000116874 "Tryptophanyl tRNA synthetase 2, mitochondrial" Q9UGM6 1 119031216-119140654 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Dystonia, Parkinsonism, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028007, HPA069692" Enhanced Supported Mitochondria NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 37: Non-specific - mRNA processing" "Cluster 20: Non-specific - Transcription regulation" 1 Mitochondria "HPA028007: , HPA069692: " "unprognostic (5.29e-2)" "unprognostic (2.57e-1)" "unprognostic (2.46e-2)" "unprognostic (1.75e-1)" "unprognostic (9.80e-2)" "unprognostic (9.75e-2)" "unprognostic (8.58e-2)" "unprognostic (1.52e-1)" "unprognostic (2.42e-2)" "potential prognostic unfavorable (3.77e-4)" "validated prognostic favorable (3.80e-9)" "validated prognostic favorable (9.26e-6)" "unprognostic (5.60e-2)" "potential prognostic unfavorable (4.53e-5)" "unprognostic (3.32e-3)" "unprognostic (1.03e-2)" "unprognostic (4.47e-2)" "unprognostic (1.08e-1)" "unprognostic (2.68e-2)" "unprognostic (8.80e-2)" "unprognostic (4.36e-1)" "unprognostic (5.30e-3)" "unprognostic (1.36e-1)" "unprognostic (9.83e-2)" "unprognostic (5.30e-2)" "unprognostic (1.31e-1)" "unprognostic (2.90e-2)" "unprognostic (1.86e-1)" "unprognostic (2.00e-1)" "unprognostic (4.13e-3)" "unprognostic (1.12e-1)" WAS "IMD2, THC, WASP, WASPA" ENSG00000015285 "WASP actin nucleation promoting factor" P42768 X 48676596-48691431 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 61.5;lymphoid tissue: 79.9" "Cell type enhanced" "Detected in many" "cDC: 104.0;Hofbauer cells: 174.0;Kupffer cells: 96.3;Macrophages: 84.8;Megakaryocyte progenitors: 68.2;Megakaryocytes: 86.5;Monocyte progenitors: 130.9;monocytes: 172.3;Neutrophil progenitors: 144.3;Neutrophils: 458.1;NK-cells: 78.0;T-cells: 72.1" "Group enriched" "Detected in many" 9 "central nervous system macrophage: 46.2;leukocyte: 54.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 45.5;neutrophil: 38.4" "Lineage enriched" "Detected in all" 4 "granulocytes: 45.5" "Group enriched" "Detected in many" 28 "Leukemia: 78.3;lymphoma: 85.9;Myeloma: 51.7" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Lung - Neutrophils_2, Minor Salivary Gland - Macrophages, Skeletal muscle - Macrophages, Spleen - Neutrophils_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA002022, CAB004290" Enhanced Approved "Plasma membrane,Cytosol" NA NA 740000 "Cluster 19: Eosinophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 52 "Plasma membrane" Cytosol "CAB004290: , HPA002022: " "unprognostic (2.81e-2)" "unprognostic (4.98e-3)" "unprognostic (3.12e-2)" "unprognostic (5.69e-3)" "unprognostic (1.21e-2)" "unprognostic (2.85e-1)" "unprognostic (1.80e-2)" "unprognostic (3.62e-1)" "unprognostic (9.25e-3)" "unprognostic (7.21e-2)" "unprognostic (2.89e-3)" "unprognostic (1.70e-1)" "unprognostic (1.80e-2)" "unprognostic (8.49e-3)" "unprognostic (3.53e-2)" "unprognostic (6.01e-3)" "unprognostic (1.46e-1)" "unprognostic (6.84e-2)" "unprognostic (4.43e-1)" "unprognostic (3.03e-1)" "unprognostic (1.70e-1)" "unprognostic (2.47e-2)" "unprognostic (7.87e-2)" "unprognostic (1.49e-1)" "unprognostic (9.28e-2)" "unprognostic (3.13e-1)" "potential prognostic favorable (2.88e-4)" "unprognostic (3.17e-1)" "unprognostic (3.94e-2)" "unprognostic (1.19e-1)" "unprognostic (4.94e-2)" WASF1 "KIAA0269, SCAR1, WAVE, WAVE1" ENSG00000112290 "WASP family member 1" Q92558 6 110099819-110180004 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 99.1;testis: 73.4" "Cell type enriched" "Detected in many" 4 "Late spermatids: 871.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "memory B-cell: 3.3;naive B-cell: 4.2;plasmacytoid DC: 8.4" "Group enriched" "Detected in many" 9 "B-cells: 4.2;dendritic cells: 8.4" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004105, CAB022161" Approved Supported NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 64 "CAB022161: , HPA004105: " "unprognostic (1.12e-1)" "unprognostic (1.59e-1)" "unprognostic (8.24e-2)" "unprognostic (1.07e-1)" "unprognostic (1.17e-1)" "unprognostic (1.74e-1)" "unprognostic (1.71e-1)" "unprognostic (4.54e-2)" "unprognostic (1.10e-1)" "unprognostic (3.42e-3)" "unprognostic (1.26e-3)" "unprognostic (1.04e-2)" "unprognostic (1.69e-3)" "potential prognostic unfavorable (4.08e-8)" "unprognostic (1.38e-3)" "potential prognostic unfavorable (6.50e-4)" "unprognostic (3.04e-3)" "unprognostic (1.21e-2)" "unprognostic (2.85e-2)" "unprognostic (3.56e-1)" "unprognostic (2.70e-1)" "unprognostic (1.31e-2)" "potential prognostic unfavorable (8.91e-4)" "unprognostic (5.01e-2)" "unprognostic (9.50e-2)" "unprognostic (1.24e-1)" "unprognostic (9.41e-2)" "unprognostic (2.65e-3)" "unprognostic (3.17e-2)" "unprognostic (2.81e-1)" "unprognostic (1.32e-1)" WASF2 "SCAR2, WAVE2" ENSG00000158195 "WASP family member 2" Q9Y6W5 1 27404230-27490167 "Predicted intracellular proteins" "Host-virus interaction" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1004.7;Esophageal suprabasal cells: 692.3" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 421.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022632, HPA045288" Enhanced Approved "Plasma membrane,Cytosol" NA NA 140000 "Cluster 40: Monocytes - Innate immune response" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 19: Astrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 24: Neutrophils - Innate immunity signal integration" 74 "Plasma membrane" Cytosol "CAB022632: , HPA045288: " "unprognostic (2.12e-1)" "unprognostic (5.19e-1)" "unprognostic (1.12e-1)" "unprognostic (1.68e-2)" "unprognostic (6.77e-2)" "unprognostic (1.11e-1)" "unprognostic (2.98e-1)" "unprognostic (6.67e-2)" "unprognostic (8.01e-3)" "unprognostic (3.76e-3)" "validated prognostic favorable (1.95e-6)" "validated prognostic favorable (2.39e-5)" "unprognostic (2.61e-1)" "potential prognostic unfavorable (5.50e-9)" "unprognostic (1.49e-3)" "unprognostic (3.79e-2)" "unprognostic (9.32e-2)" "unprognostic (9.96e-2)" "unprognostic (2.90e-1)" "potential prognostic unfavorable (5.14e-5)" "unprognostic (1.69e-1)" "unprognostic (2.72e-2)" "unprognostic (3.75e-1)" "unprognostic (8.80e-2)" "unprognostic (9.32e-2)" "unprognostic (1.04e-3)" "unprognostic (2.20e-1)" "unprognostic (1.48e-1)" "unprognostic (2.54e-1)" "unprognostic (2.57e-2)" "unprognostic (4.07e-1)" WASF3 "KIAA0900, SCAR3, WAVE3" ENSG00000132970 "WASP family member 3" Q9UPY6 13 26557683-26688948 "Cancer-related genes, Predicted intracellular proteins" Actin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 58.7;retina: 52.2" "Cell type enhanced" "Detected in many" "Astrocytes: 245.1;Bergmann glia: 408.3;Cone photoreceptor cells: 165.6;Granulosa cells: 195.4;Pituicytes/FSCs: 316.3;Retinal horizontal cells: 236.4;Rod photoreceptor cells: 170.4" "Cell type enhanced" "Detected in all" "Bergmann glia: 412.8" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 24.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037086, HPA066228" Enhanced NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 1: Neuronal - Visual perception" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 7 "CAB037086: , HPA066228: " "potential prognostic favorable (6.97e-4)" "unprognostic (4.62e-1)" "unprognostic (1.16e-1)" "unprognostic (8.43e-2)" "unprognostic (4.43e-2)" "unprognostic (6.47e-2)" "unprognostic (1.09e-1)" "unprognostic (9.15e-2)" "unprognostic (3.38e-1)" "unprognostic (1.04e-2)" "unprognostic (2.88e-2)" "unprognostic (1.49e-1)" "unprognostic (1.22e-1)" "unprognostic (3.67e-2)" "unprognostic (3.84e-2)" "unprognostic (2.64e-3)" "unprognostic (9.17e-2)" "unprognostic (3.58e-2)" "unprognostic (1.82e-1)" "unprognostic (9.40e-2)" "unprognostic (2.94e-2)" "unprognostic (1.02e-3)" "unprognostic (2.94e-1)" "unprognostic (3.83e-2)" "unprognostic (5.65e-2)" "unprognostic (1.23e-2)" "unprognostic (2.24e-1)" "unprognostic (5.47e-2)" "unprognostic (2.32e-2)" "unprognostic (3.88e-3)" "unprognostic (1.88e-1)" WASH6P "CXYorf1, FAM39A" ENSG00000182484 "WASP family homolog 6, pseudogene" X 156020826-156025710 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 22.9;Hematopoietic stem cells: 73.3;Kupffer cells: 40.0;Mast cells: 82.9;Megakaryocyte progenitors: 45.1;Megakaryocyte-Erythroid progenitors: 75.0;Megakaryocytes: 24.7;Urothelial cells: 37.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002689 Uncertain Approved Vesicles NA NA "Cluster 24: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 62: Non-specific - Plasma proteins" "Cluster 58: Mast cells - Allergic inflammatory responses" Vesicles "HPA002689: " "unprognostic (4.30e-2)" "unprognostic (2.67e-1)" "unprognostic (1.05e-1)" "unprognostic (1.11e-2)" "unprognostic (9.14e-2)" "unprognostic (6.66e-2)" "unprognostic (1.37e-1)" "unprognostic (3.71e-2)" "unprognostic (5.88e-3)" "unprognostic (7.45e-2)" "unprognostic (1.13e-1)" "unprognostic (1.92e-2)" "unprognostic (7.40e-2)" "unprognostic (1.05e-2)" "unprognostic (4.72e-2)" "unprognostic (2.24e-1)" "potential prognostic favorable (2.87e-4)" "unprognostic (2.10e-2)" "unprognostic (1.81e-2)" "unprognostic (1.16e-1)" "unprognostic (1.26e-1)" "unprognostic (9.87e-2)" "unprognostic (2.62e-1)" "unprognostic (2.96e-3)" "unprognostic (5.57e-1)" "unprognostic (1.10e-1)" "unprognostic (6.41e-2)" WASHC1 "FAM39E, FLJ00038, WASH1" ENSG00000181404 "WASH complex subunit 1" A8K0Z3 9 14475-73865 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 105.9;Loop of henle epithelial cells: 94.0;Papillary tip epithelial cells: 85.0;Podocytes: 326.8;Proximal tubule cells: 145.1;Renal collecting duct intercalated cells: 108.1;Renal collecting duct principal cells: 125.2;Renal connecting tubule cells: 109.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA002689 Uncertain Supported Vesicles NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 64: Non-specific - Transcription" "Cluster 46: Brainstem - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 57: Podocytes - Glomerular filtration" 20 Vesicles "HPA002689: " "unprognostic (3.50e-2)" "unprognostic (1.74e-1)" "unprognostic (6.33e-3)" "unprognostic (2.10e-3)" "unprognostic (2.02e-2)" "unprognostic (5.08e-1)" "unprognostic (2.12e-1)" "unprognostic (5.21e-2)" "unprognostic (2.97e-2)" "unprognostic (2.25e-2)" "unprognostic (3.39e-1)" "unprognostic (7.03e-2)" "potential prognostic unfavorable (7.90e-5)" "unprognostic (1.64e-1)" "unprognostic (1.37e-1)" "unprognostic (3.31e-1)" "unprognostic (3.47e-2)" "unprognostic (3.51e-1)" "unprognostic (5.22e-3)" "unprognostic (3.24e-3)" "unprognostic (5.08e-2)" "unprognostic (2.48e-1)" "unprognostic (1.57e-1)" "unprognostic (4.29e-2)" "unprognostic (1.71e-2)" "unprognostic (2.71e-1)" "unprognostic (2.56e-1)" "unprognostic (2.38e-1)" "unprognostic (1.52e-1)" WASHC2A "bA56A21.1, bA98I6.1, FAM21A, FAM21B, FLJ10824" ENSG00000099290 "WASH complex subunit 2A" Q641Q2 10 50067888-50133509 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA047844, HPA060975, HPA061022" Supported Supported Nucleoli,Vesicles,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 35: Non-specific - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 17 Vesicles "Nucleoli, Cytosol" "HPA047844: , HPA060975: , HPA061022: " "unprognostic (1.35e-2)" "unprognostic (1.13e-1)" "unprognostic (7.94e-3)" "unprognostic (3.82e-2)" "unprognostic (1.01e-1)" "unprognostic (1.45e-1)" "unprognostic (4.57e-2)" "unprognostic (7.59e-3)" "unprognostic (1.02e-1)" "potential prognostic favorable (1.34e-4)" "unprognostic (6.36e-3)" "unprognostic (6.19e-2)" "unprognostic (1.09e-3)" "unprognostic (1.49e-1)" "unprognostic (1.76e-1)" "unprognostic (2.70e-1)" "unprognostic (2.82e-1)" "unprognostic (7.68e-3)" "unprognostic (1.01e-1)" "unprognostic (1.56e-1)" "unprognostic (8.31e-2)" "unprognostic (3.92e-2)" "potential prognostic favorable (5.94e-4)" "unprognostic (2.84e-1)" "unprognostic (8.79e-2)" "unprognostic (4.48e-1)" "unprognostic (1.78e-1)" "unprognostic (2.44e-1)" "unprognostic (1.94e-1)" WASHC2C "Em:AC012044.3, FAM21C, KIAA0592" ENSG00000172661 "WASH complex subunit 2C" Q9Y4E1 10 45727200-45792964 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 96.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA047844, HPA060975, HPA061022" Supported Supported Nucleoli,Vesicles,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 61: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 52: Non-specific - Mitochondria" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" 15 Vesicles "Nucleoli, Cytosol" "HPA047844: , HPA060975: , HPA061022: " "unprognostic (2.01e-1)" "unprognostic (1.59e-2)" "unprognostic (4.30e-1)" "unprognostic (6.90e-2)" "unprognostic (1.02e-1)" "unprognostic (2.08e-2)" "potential prognostic favorable (2.11e-5)" "unprognostic (3.91e-2)" "unprognostic (6.61e-3)" "potential prognostic favorable (1.56e-7)" "unprognostic (1.42e-2)" "unprognostic (1.19e-1)" "unprognostic (2.46e-3)" "unprognostic (1.61e-2)" "unprognostic (2.65e-1)" "unprognostic (1.89e-1)" "unprognostic (7.52e-2)" "unprognostic (5.50e-2)" "unprognostic (7.92e-2)" "unprognostic (3.82e-2)" "unprognostic (2.41e-2)" "unprognostic (1.15e-1)" "unprognostic (3.49e-2)" "unprognostic (2.55e-1)" "unprognostic (8.61e-2)" "unprognostic (1.08e-1)" "unprognostic (2.49e-1)" "unprognostic (1.91e-2)" "unprognostic (9.38e-2)" WASHC3 "CCDC53, CGI-116" ENSG00000120860 "WASH complex subunit 3" Q9Y3C0 12 102012840-102062149 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Early spermatids: 885.2;Late primary spermatocytes: 702.6;Late spermatids: 2084.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038339 Uncertain Approved Vesicles NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 67: Testis - Mixed function" "Cluster 27: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 107 Vesicles "HPA038339: " "unprognostic (1.15e-1)" "unprognostic (3.73e-1)" "unprognostic (3.99e-2)" "unprognostic (1.05e-1)" "unprognostic (1.24e-1)" "unprognostic (2.43e-3)" "unprognostic (6.72e-2)" "unprognostic (3.72e-2)" "unprognostic (3.95e-1)" "unprognostic (2.07e-2)" "unprognostic (4.40e-1)" "unprognostic (1.86e-1)" "unprognostic (7.31e-2)" "unprognostic (1.43e-1)" "unprognostic (1.04e-3)" "unprognostic (4.33e-2)" "unprognostic (7.75e-2)" "unprognostic (2.15e-1)" "unprognostic (2.24e-2)" "unprognostic (2.14e-1)" "unprognostic (1.49e-1)" "unprognostic (1.06e-1)" "unprognostic (7.32e-2)" "unprognostic (9.56e-2)" "unprognostic (1.37e-1)" "unprognostic (1.54e-1)" "unprognostic (1.81e-1)" "unprognostic (1.01e-1)" "unprognostic (5.08e-3)" WASHC4 "KIAA1033, SWIP" ENSG00000136051 "WASH complex subunit 4" Q2M389 12 105107324-105169130 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglia: 300.4;Neutrophil progenitors: 374.1;Neutrophils: 446.5" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 392.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045666, HPA046737" Uncertain Enhanced Nucleoplasm NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 30: White matter - Myelination" "Cluster 38: Non-specific - Transcription" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 26 Nucleoplasm "HPA045666: , HPA046737: " "unprognostic (3.16e-2)" "unprognostic (9.03e-2)" "unprognostic (9.04e-3)" "unprognostic (1.82e-1)" "unprognostic (6.07e-3)" "unprognostic (4.33e-2)" "unprognostic (1.29e-2)" "unprognostic (1.20e-1)" "unprognostic (1.39e-2)" "unprognostic (8.26e-3)" "unprognostic (1.22e-2)" "unprognostic (1.40e-1)" "unprognostic (2.32e-2)" "unprognostic (2.00e-2)" "unprognostic (1.01e-1)" "unprognostic (1.72e-1)" "unprognostic (1.59e-1)" "unprognostic (7.63e-3)" "unprognostic (1.51e-3)" "unprognostic (3.84e-2)" "unprognostic (1.20e-3)" "unprognostic (1.50e-2)" "unprognostic (1.06e-1)" "unprognostic (2.53e-1)" "unprognostic (1.03e-1)" "unprognostic (8.01e-2)" "unprognostic (3.85e-1)" "unprognostic (5.18e-2)" "unprognostic (9.95e-2)" WASHC5 "KIAA0196, SPG8" ENSG00000164961 "WASH complex subunit 5" Q12768 8 125024260-125091819 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant, Hereditary spastic paraplegia, Intellectual disability, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 139.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034216, CAB034219" Supported Supported "Cytokinetic bridge,Mitotic spindle,Primary cilium,Centrosome,Basal body,Cytosol" Yes NA "Cluster 33: Non-specific - ATP binding" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 32 Cytosol "Cytokinetic bridge, Mitotic spindle, Primary cilium, Centrosome, Basal body" "CAB034216: , CAB034219: " "unprognostic (1.06e-1)" "unprognostic (2.57e-3)" "unprognostic (1.35e-2)" "unprognostic (3.01e-1)" "unprognostic (5.28e-2)" "unprognostic (9.89e-2)" "unprognostic (6.83e-2)" "unprognostic (1.30e-1)" "potential prognostic unfavorable (6.14e-5)" "potential prognostic favorable (1.50e-6)" "unprognostic (1.73e-2)" "unprognostic (1.13e-1)" "potential prognostic unfavorable (2.90e-4)" "unprognostic (2.19e-2)" "unprognostic (6.11e-2)" "unprognostic (4.27e-2)" "unprognostic (9.14e-2)" "unprognostic (8.26e-2)" "unprognostic (9.85e-3)" "unprognostic (2.13e-3)" "unprognostic (1.43e-3)" "unprognostic (7.01e-2)" "unprognostic (1.40e-1)" "unprognostic (2.75e-1)" "unprognostic (4.14e-1)" "unprognostic (1.31e-1)" "unprognostic (2.79e-1)" "unprognostic (1.05e-1)" "unprognostic (3.34e-1)" WASL "N-WASP, NWASP, WASPB" ENSG00000106299 "WASP like actin nucleation promoting factor" O00401 7 123681943-123749003 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Transcription, Transcription regulation" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 421.1;Podocytes: 368.1;Urothelial cells: 386.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005399, HPA005750" Supported Approved Nucleoli,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 76: Non-specific - Metabolism" "Cluster 51: Neurons - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 69: Urothelial cells - Basic cellular functions" 75 Cytosol Nucleoli "CAB005399: , HPA005750: " "unprognostic (1.57e-2)" "unprognostic (1.61e-1)" "unprognostic (1.72e-2)" "unprognostic (7.10e-3)" "unprognostic (3.05e-1)" "unprognostic (2.24e-2)" "unprognostic (3.72e-1)" "unprognostic (4.00e-3)" "unprognostic (8.20e-2)" "potential prognostic unfavorable (5.69e-4)" "potential prognostic favorable (1.57e-8)" "unprognostic (3.53e-3)" "unprognostic (1.59e-2)" "unprognostic (2.31e-2)" "unprognostic (4.22e-2)" "unprognostic (2.21e-2)" "unprognostic (3.15e-2)" "unprognostic (2.31e-1)" "unprognostic (7.46e-2)" "unprognostic (1.43e-1)" "unprognostic (1.09e-1)" "potential prognostic unfavorable (3.77e-4)" "unprognostic (1.04e-1)" "unprognostic (1.24e-1)" "unprognostic (2.87e-1)" "unprognostic (9.18e-2)" "unprognostic (9.23e-2)" "unprognostic (7.50e-2)" "unprognostic (3.93e-1)" "unprognostic (9.42e-2)" "unprognostic (1.58e-1)" WBP1 WBP-1 ENSG00000239779 "WW domain binding protein 1" Q96G27 2 74458400-74460891 "Essential proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 22.7;Bergmann glia: 29.1;Brain excitatory neurons: 12.1;Brain inhibitory neurons: 13.1;Choroid plexus epithelial cells: 8.5;Ependymal cells: 24.6;Microglia: 14.5;Oligodendrocyte progenitor cells: 16.5;Oligodendrocytes: 26.4;Other brain neurons: 15.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057067 Approved Approved Cytosol No No "Cluster 13: Non-specific - Mitochondria" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" 7 Cytosol "HPA057067: " "unprognostic (7.20e-2)" "unprognostic (1.21e-1)" "unprognostic (2.18e-1)" "unprognostic (7.46e-3)" "unprognostic (2.50e-3)" "unprognostic (1.34e-2)" "unprognostic (2.69e-1)" "potential prognostic favorable (3.37e-4)" "unprognostic (8.30e-2)" "unprognostic (5.75e-2)" "potential prognostic favorable (3.32e-7)" "unprognostic (2.08e-2)" "unprognostic (1.82e-2)" "unprognostic (3.46e-1)" "potential prognostic unfavorable (6.19e-4)" "unprognostic (1.15e-1)" "unprognostic (1.03e-1)" "unprognostic (6.15e-2)" "unprognostic (1.19e-1)" "unprognostic (3.02e-1)" "unprognostic (9.72e-2)" "unprognostic (1.04e-1)" "unprognostic (4.00e-1)" "unprognostic (6.24e-2)" "unprognostic (3.91e-1)" "unprognostic (3.81e-2)" "unprognostic (2.47e-2)" "unprognostic (3.35e-3)" "unprognostic (8.92e-2)" "unprognostic (1.26e-2)" "unprognostic (6.10e-2)" WBP11 "BUG13, NPWBP, PPP1R165, SIPP1" ENSG00000084463 "WW domain binding protein 11" Q9Y2W2 12 14784582-14803486 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing, rRNA processing" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 278.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "HPA039710, HPA040037, HPA046403, HPA049126" Approved Supported "Nucleoplasm,Vesicles,Cytosol,Acrosome,Principal piece,End piece" NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 45 Nucleoplasm "Vesicles, Cytosol, Acrosome, Principal piece, End piece" "HPA039710: , HPA040037: , HPA046403: , HPA049126: " "unprognostic (3.84e-1)" "unprognostic (5.10e-2)" "unprognostic (1.10e-2)" "unprognostic (3.84e-1)" "unprognostic (8.50e-2)" "unprognostic (5.19e-2)" "unprognostic (2.00e-1)" "unprognostic (9.08e-2)" "unprognostic (1.00e-1)" "unprognostic (4.11e-2)" "potential prognostic favorable (9.39e-5)" "unprognostic (7.43e-3)" "unprognostic (1.78e-1)" "unprognostic (5.66e-3)" "unprognostic (7.58e-3)" "unprognostic (1.37e-3)" "unprognostic (1.03e-2)" "unprognostic (3.82e-2)" "unprognostic (1.84e-1)" "unprognostic (1.09e-1)" "unprognostic (2.45e-1)" "unprognostic (2.20e-1)" "potential prognostic unfavorable (3.43e-4)" "unprognostic (3.67e-1)" "unprognostic (6.98e-2)" "unprognostic (1.74e-2)" "unprognostic (1.84e-2)" "unprognostic (2.68e-1)" "unprognostic (1.83e-1)" "unprognostic (8.21e-2)" "unprognostic (9.16e-2)" WBP1L "C10orf26, FLJ20154, OPAL1" ENSG00000166272 "WW domain binding protein 1 like" Q9NX94 10 102743948-102834516 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Late spermatids: 795.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037635, HPA038371" Uncertain Approved Nucleoplasm,Microtubules NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 44: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 15 Microtubules Nucleoplasm "HPA037635: , HPA038371: " "unprognostic (5.02e-2)" "unprognostic (1.95e-1)" "unprognostic (1.18e-1)" "unprognostic (1.69e-1)" "unprognostic (4.77e-2)" "unprognostic (1.26e-1)" "unprognostic (1.78e-2)" "unprognostic (3.08e-2)" "unprognostic (6.99e-2)" "potential prognostic favorable (7.42e-8)" "unprognostic (6.73e-3)" "unprognostic (8.18e-2)" "unprognostic (9.33e-2)" "unprognostic (1.94e-1)" "unprognostic (1.58e-1)" "unprognostic (2.86e-2)" "unprognostic (1.19e-1)" "unprognostic (1.36e-3)" "potential prognostic unfavorable (4.59e-5)" "unprognostic (9.12e-2)" "unprognostic (3.79e-1)" "unprognostic (3.13e-1)" "unprognostic (4.71e-2)" "unprognostic (5.94e-2)" "unprognostic (1.39e-1)" "unprognostic (2.41e-2)" "unprognostic (3.44e-1)" "unprognostic (4.59e-2)" "unprognostic (1.66e-2)" WBP2 "GRAMD6, WBP-2" ENSG00000132471 "WW domain binding protein 2" Q969T9 17 75845699-75856507 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 342.2;Esophageal apical cells: 279.2;Late spermatids: 484.7;Platelets: 904.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065682, HPA068819" Approved Supported Nucleoplasm,Cytosol No No 97000 "Cluster 21: Neutrophils - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 47: Platelets - Hemostasis" 28 "Nucleoplasm, Cytosol" "HPA065682: , HPA068819: " "unprognostic (2.00e-2)" "unprognostic (2.07e-2)" "unprognostic (1.70e-1)" "unprognostic (2.93e-1)" "unprognostic (1.20e-1)" "potential prognostic unfavorable (2.24e-4)" "unprognostic (8.59e-2)" "unprognostic (5.01e-1)" "unprognostic (9.44e-3)" "unprognostic (2.13e-2)" "unprognostic (3.19e-3)" "unprognostic (1.60e-2)" "unprognostic (3.83e-2)" "unprognostic (8.48e-3)" "unprognostic (3.94e-2)" "unprognostic (1.97e-1)" "unprognostic (9.37e-2)" "unprognostic (9.64e-3)" "unprognostic (1.40e-1)" "unprognostic (2.79e-1)" "unprognostic (1.83e-1)" "unprognostic (2.56e-2)" "unprognostic (8.27e-2)" "unprognostic (1.34e-1)" "unprognostic (2.92e-2)" "unprognostic (5.67e-2)" "unprognostic (2.02e-1)" "unprognostic (3.95e-2)" "unprognostic (2.17e-1)" "unprognostic (1.19e-1)" "unprognostic (1.14e-1)" WBP2NL "FLJ26145, GRAMD7, MGC26816, PAWP" ENSG00000183066 "WBP2 N-terminal like" Q6ICG8 22 41998725-42058456 "Predicted intracellular proteins" Meiosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "testis: 17.4" "Group enriched" "Detected in many" 6 "Early spermatids: 398.7;Late spermatids: 1365.1" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebellum: 5.5" HPA048557 Enhanced Uncertain Cytosol NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 30: White matter - Myelination" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 6 Cytosol "HPA048557: " "unprognostic (1.12e-1)" "unprognostic (1.75e-1)" "unprognostic (8.91e-2)" "unprognostic (6.79e-2)" WBP4 "FBP21, MGC117310" ENSG00000120688 "WW domain binding protein 4" O75554 13 41061509-41084006 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038965, HPA058738" Approved Supported "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 37 Nucleoplasm "Vesicles, Plasma membrane" "HPA038965: , HPA058738: " "unprognostic (7.14e-2)" "unprognostic (2.68e-1)" "unprognostic (6.59e-2)" "potential prognostic unfavorable (8.68e-4)" "unprognostic (1.88e-1)" "unprognostic (1.65e-1)" "unprognostic (7.98e-2)" "unprognostic (9.39e-2)" "unprognostic (2.35e-3)" "unprognostic (8.70e-2)" "potential prognostic favorable (6.30e-6)" "unprognostic (3.97e-3)" "unprognostic (2.06e-2)" "unprognostic (5.71e-2)" "unprognostic (1.06e-3)" "unprognostic (1.62e-2)" "unprognostic (9.26e-2)" "unprognostic (3.14e-1)" "unprognostic (2.94e-2)" "unprognostic (9.17e-2)" "unprognostic (6.33e-3)" "unprognostic (1.30e-2)" "unprognostic (1.54e-2)" "unprognostic (1.10e-1)" "unprognostic (9.94e-2)" "unprognostic (2.41e-2)" "unprognostic (9.53e-3)" "unprognostic (1.45e-1)" "unprognostic (6.13e-2)" "unprognostic (1.41e-1)" "unprognostic (3.21e-2)" WDCP "C2orf44, FLJ21945, MMAP" ENSG00000163026 "WD repeat and coiled coil containing" Q9H6R7 2 24029347-24049575 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 21.3;Early primary spermatocytes: 17.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041054 Approved Approved Nucleoli,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 65: Non-specific - Cell growth & division" 22 Nucleoli Cytosol "HPA041054: " "unprognostic (3.78e-1)" "unprognostic (4.91e-2)" "unprognostic (1.04e-1)" "unprognostic (9.90e-2)" "unprognostic (1.24e-2)" "unprognostic (1.93e-1)" "unprognostic (6.28e-2)" "unprognostic (1.45e-1)" "unprognostic (3.82e-2)" "unprognostic (1.17e-2)" "unprognostic (3.48e-2)" "unprognostic (2.10e-2)" "potential prognostic unfavorable (2.19e-8)" "unprognostic (3.16e-2)" "unprognostic (6.33e-2)" "unprognostic (3.02e-2)" "unprognostic (3.54e-2)" "unprognostic (5.73e-2)" "unprognostic (7.42e-2)" "unprognostic (3.85e-1)" "unprognostic (1.18e-1)" "unprognostic (2.23e-2)" "unprognostic (9.57e-3)" "unprognostic (2.32e-1)" "unprognostic (3.18e-3)" "unprognostic (2.18e-1)" "unprognostic (1.78e-1)" "unprognostic (3.74e-2)" "unprognostic (2.05e-1)" WDFY1 "FENS-1, KIAA1435, WDF1, ZFYVE17" ENSG00000085449 "WD repeat and FYVE domain containing 1" Q8IWB7 2 223855716-223945357 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 51.2;Bergmann glia: 42.6;Brain excitatory neurons: 43.6;Brain inhibitory neurons: 41.9;Choroid plexus epithelial cells: 74.1;Distal convoluted tubule cells: 49.3;Ependymal cells: 38.2;Loop of henle epithelial cells: 49.5;Microglia: 66.2;Oligodendrocyte progenitor cells: 61.6;Oligodendrocytes: 63.2;Other brain neurons: 34.7;Papillary tip epithelial cells: 46.5;Podocytes: 72.5;Proximal tubule cells: 54.0;Renal collecting duct intercalated cells: 45.0;Renal collecting duct principal cells: 41.0;Renal connecting tubule cells: 52.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050603, HPA079597" Approved Supported "Golgi apparatus,Vesicles" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 61: Non-specific - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 102: Non-specific - Mixed function" 22 "Golgi apparatus, Vesicles" "HPA050603: , HPA079597: " "unprognostic (5.29e-3)" "unprognostic (5.27e-2)" "potential prognostic favorable (1.83e-4)" "unprognostic (1.00e-1)" "unprognostic (1.82e-1)" "unprognostic (3.68e-2)" "unprognostic (1.99e-1)" "unprognostic (3.16e-1)" "unprognostic (3.15e-2)" "unprognostic (4.62e-2)" "potential prognostic favorable (8.50e-5)" "unprognostic (1.01e-2)" "unprognostic (6.58e-2)" "unprognostic (6.61e-2)" "unprognostic (1.02e-1)" "unprognostic (2.24e-3)" "unprognostic (2.85e-2)" "unprognostic (3.01e-1)" "unprognostic (2.40e-1)" "unprognostic (5.65e-2)" "unprognostic (1.01e-1)" "unprognostic (1.45e-3)" "potential prognostic unfavorable (1.91e-4)" "unprognostic (9.85e-2)" "unprognostic (2.77e-1)" "unprognostic (8.63e-3)" "unprognostic (8.79e-2)" "unprognostic (6.37e-2)" "unprognostic (2.86e-1)" "unprognostic (4.37e-1)" "unprognostic (2.48e-1)" WDFY2 ZFYVE22 ENSG00000139668 "WD repeat and FYVE domain containing 2" Q96P53 13 51584455-51767709 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adrenal cortex cells: 709.6;Distal convoluted tubule cells: 582.3;Pancreatic acinar cells: 600.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary gland basal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050094 Supported Vesicles NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 58: Skin - Keratinization" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 6 Vesicles "HPA050094: " "unprognostic (2.19e-1)" "unprognostic (3.11e-2)" "unprognostic (3.31e-2)" "unprognostic (1.91e-1)" "unprognostic (8.49e-3)" "unprognostic (7.28e-3)" "unprognostic (1.50e-1)" "unprognostic (1.09e-1)" "unprognostic (3.13e-1)" "unprognostic (1.61e-1)" "unprognostic (2.36e-1)" "unprognostic (2.20e-2)" "unprognostic (4.08e-2)" "unprognostic (6.06e-3)" "unprognostic (2.77e-1)" "unprognostic (6.09e-2)" "unprognostic (2.09e-2)" "unprognostic (3.71e-1)" "unprognostic (4.05e-2)" "unprognostic (2.80e-2)" "unprognostic (3.29e-1)" "unprognostic (1.90e-1)" "potential prognostic unfavorable (1.79e-4)" "unprognostic (1.02e-1)" "unprognostic (6.58e-2)" "unprognostic (3.97e-2)" "unprognostic (1.56e-1)" "unprognostic (9.21e-2)" "unprognostic (6.57e-2)" "unprognostic (6.55e-2)" "unprognostic (2.21e-2)" WDFY3 "ALFY, KIAA0993, ZFYVE25" ENSG00000163625 "WD repeat and FYVE domain containing 3" Q8IZQ1 4 84668765-84966690 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Autophagy "Developmental protein" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 878.7;Neutrophils: 3004.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "neutrophil: 1.4" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.4" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042734, HPA048572" Approved Approved "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 25 Cytosol "Nucleoli, Plasma membrane" "HPA042734: , HPA048572: " "unprognostic (5.07e-2)" "unprognostic (1.52e-1)" "unprognostic (4.26e-1)" "unprognostic (9.30e-3)" "unprognostic (3.41e-2)" "unprognostic (7.93e-2)" "unprognostic (1.62e-2)" "unprognostic (4.99e-3)" "unprognostic (2.10e-1)" "unprognostic (9.94e-2)" "validated prognostic favorable (7.06e-8)" "validated prognostic favorable (2.77e-6)" "unprognostic (2.59e-2)" "unprognostic (1.99e-2)" "unprognostic (1.21e-1)" "unprognostic (1.73e-1)" "unprognostic (1.78e-2)" "unprognostic (2.24e-1)" "unprognostic (4.54e-2)" "unprognostic (2.80e-2)" "unprognostic (6.63e-2)" "unprognostic (1.92e-1)" "unprognostic (5.01e-3)" "unprognostic (1.13e-1)" "unprognostic (7.45e-3)" "unprognostic (1.07e-1)" "unprognostic (2.85e-1)" "unprognostic (1.39e-2)" "unprognostic (2.14e-1)" "unprognostic (1.77e-2)" "unprognostic (3.21e-1)" WDFY4 "C10orf64, Em:AC060234.3, FLJ45748, KIAA1607" ENSG00000128815 "WDFY family member 4" Q6ZS81 10 48684873-48982956 "Predicted intracellular proteins, Predicted membrane proteins" Autophagy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 11.0;lymphoid tissue: 26.6" "Cell type enhanced" "Detected in many" "B-cells: 336.3;cDC: 683.0;Early spermatids: 128.7;Macrophages: 129.5;Microglia: 419.1;Monocyte progenitors: 90.6;Neutrophil progenitors: 84.6;Neutrophils: 133.0;pDCs: 362.1" "Group enriched" "Detected in many" 4 "central nervous system macrophage: 546.4;pericyte: 215.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "memory B-cell: 14.2;myeloid DC: 11.3;naive B-cell: 20.9;neutrophil: 9.8;plasmacytoid DC: 32.1" "Group enriched" "Detected in many" 7 "B-cells: 20.9;dendritic cells: 32.1;granulocytes: 9.8" "Group enriched" "Detected in some" 9 "Leukemia: 13.8;lymphoma: 35.4" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Lung - Macrophages, Spleen - B-cells (Spleen), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA040634 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 82: Dendritic cells - Antigen presentation" Nucleoplasm Cytosol "HPA040634: " "unprognostic (2.87e-1)" "unprognostic (2.89e-2)" "unprognostic (6.13e-3)" "unprognostic (6.07e-2)" "unprognostic (2.42e-1)" "unprognostic (3.01e-1)" "unprognostic (1.16e-1)" "unprognostic (1.02e-1)" "potential prognostic favorable (2.31e-5)" "unprognostic (5.79e-2)" "unprognostic (6.63e-2)" "unprognostic (1.22e-1)" "unprognostic (1.04e-2)" "unprognostic (9.32e-3)" "unprognostic (8.01e-3)" "unprognostic (4.97e-2)" "unprognostic (3.81e-1)" "unprognostic (2.30e-1)" "unprognostic (7.17e-2)" "unprognostic (4.09e-1)" "unprognostic (8.10e-2)" "unprognostic (1.77e-1)" "unprognostic (5.29e-2)" "unprognostic (5.79e-3)" "unprognostic (2.02e-1)" "unprognostic (1.23e-2)" "unprognostic (7.86e-2)" "unprognostic (5.74e-2)" WDHD1 "AND-1, CHTF4, CTF4" ENSG00000198554 "WD repeat and HMG-box DNA binding protein 1" O75717 14 54938949-55027105 "Essential proteins, Predicted intracellular proteins, Predicted membrane proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 7.5" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 87.5;Early primary spermatocytes: 67.2;Erythrocyte progenitors: 179.1;Megakaryocyte progenitors: 95.1;Megakaryocyte-Erythroid progenitors: 57.4;Monocyte progenitors: 79.5;Neutrophil progenitors: 56.1;Undifferentiated spermatogonia: 47.5" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 30.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000632, HPA001122" Enhanced Enhanced Nucleoplasm NA Yes "Cluster 5: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 34: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 17 Nucleoplasm "HPA000632: , HPA001122: " "unprognostic (2.72e-2)" "unprognostic (3.17e-1)" "unprognostic (5.49e-2)" "unprognostic (1.91e-2)" "unprognostic (6.77e-2)" "unprognostic (8.11e-3)" "unprognostic (3.21e-1)" "unprognostic (1.36e-1)" "unprognostic (4.04e-2)" "potential prognostic unfavorable (2.79e-4)" "unprognostic (1.32e-3)" "unprognostic (2.98e-1)" "unprognostic (2.22e-1)" "potential prognostic unfavorable (5.58e-5)" "potential prognostic unfavorable (4.44e-4)" "unprognostic (4.37e-3)" "unprognostic (2.00e-2)" "unprognostic (4.33e-2)" "unprognostic (2.68e-1)" "unprognostic (1.72e-1)" "unprognostic (3.19e-3)" "unprognostic (5.96e-3)" "unprognostic (5.52e-3)" "unprognostic (1.59e-1)" "unprognostic (8.84e-2)" "unprognostic (9.61e-2)" "unprognostic (4.33e-1)" "unprognostic (1.53e-1)" "unprognostic (7.98e-2)" WDPCP "BBS15, C2orf86, CPLANE5, fritz, hFrtz" ENSG00000143951 "WD repeat containing planar cell polarity effector" O95876 2 63119559-63827843 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Intellectual disability, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 2892.7;Cardiomyocytes: 2295.1;Myonuclei: 948.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044144 Uncertain Approved "Nuclear bodies,Endoplasmic reticulum,Flagellar centriole" NA No "Cluster 20: Non-specific - DNA binding" "Cluster 40: Non-specific - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 56: Non-specific - Sensory perception" "Cluster 89: Adipocytes - Lipid metabolism" "Nuclear bodies, Flagellar centriole" "Endoplasmic reticulum" "HPA044144: " "unprognostic (2.72e-1)" "unprognostic (5.49e-3)" "unprognostic (7.75e-2)" "unprognostic (4.53e-3)" "unprognostic (3.80e-2)" "unprognostic (1.60e-1)" "unprognostic (1.83e-3)" "unprognostic (1.13e-1)" "unprognostic (9.66e-3)" "unprognostic (3.52e-1)" "unprognostic (1.14e-1)" "unprognostic (1.36e-1)" "unprognostic (2.35e-1)" "unprognostic (1.16e-2)" "unprognostic (5.30e-2)" "unprognostic (2.03e-2)" "unprognostic (9.79e-3)" "unprognostic (2.53e-2)" "unprognostic (1.03e-2)" "unprognostic (1.48e-1)" "unprognostic (1.74e-1)" "unprognostic (6.42e-3)" "unprognostic (5.51e-2)" "unprognostic (2.50e-2)" "potential prognostic favorable (7.42e-4)" "unprognostic (2.62e-3)" "unprognostic (2.01e-1)" "unprognostic (2.27e-2)" "unprognostic (5.93e-3)" "unprognostic (9.97e-3)" WDR1 AIP1 ENSG00000071127 "WD repeat domain 1" O75083 4 10068089-10116972 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 562.5;Late spermatids: 1760.1;Megakaryocytes: 649.1;Platelets: 1221.3" "Cell type enhanced" "Detected in all" "vascular associated smooth muscle cell: 128.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Prostate - Smooth muscle cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020804, HPA036434, HPA070293" Approved Supported "Plasma membrane,Cell Junctions,Cytosol" NA NA 66000000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 55: Breast - Lactation" "Cluster 21: Non-specific - Metabolism" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 62: Smooth muscle cells - Muscle contraction" 34 "Plasma membrane, Cell Junctions, Cytosol" "CAB020804: , HPA036434: , HPA070293: " "unprognostic (1.56e-2)" "unprognostic (3.07e-1)" "unprognostic (1.60e-1)" "unprognostic (4.43e-2)" "potential prognostic favorable (3.18e-4)" "unprognostic (2.44e-2)" "unprognostic (2.39e-1)" "unprognostic (5.30e-1)" "unprognostic (6.37e-2)" "unprognostic (3.32e-3)" "potential prognostic favorable (1.77e-6)" "unprognostic (3.19e-2)" "unprognostic (5.94e-3)" "unprognostic (3.70e-3)" "unprognostic (2.10e-2)" "validated prognostic unfavorable (8.01e-6)" "validated prognostic unfavorable (6.17e-4)" "unprognostic (4.04e-2)" "unprognostic (2.24e-2)" "unprognostic (9.87e-2)" "unprognostic (3.43e-1)" "unprognostic (4.46e-2)" "unprognostic (8.22e-2)" "unprognostic (2.36e-1)" "unprognostic (2.55e-1)" "unprognostic (1.80e-1)" "unprognostic (1.35e-1)" "unprognostic (5.81e-2)" "unprognostic (1.72e-1)" "unprognostic (1.91e-1)" "unprognostic (3.46e-2)" WDR11 "BRWD2, DR11, FLJ10506, HH14, KIAA1351, SRI1, WDR15" ENSG00000120008 "WD repeat domain 11" Q9BZH6 10 120851305-120909524 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Hypogonadotropic hypogonadism, Intellectual disability, Kallmann syndrome, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Bergmann glia: 211.6;Gastric progenitor cells: 488.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038980 Approved Supported "Vesicles,Plasma membrane,Microtubules,Primary cilium,Cytosol,Flagellar centriole,Principal piece,End piece" NA NA 3400 "Cluster 42: Non-specific - Vesicular transport" "Cluster 61: Non-specific - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 7: Non-specific - Transcription" 22 "Microtubules, Primary cilium, End piece" "Vesicles, Plasma membrane, Cytosol, Flagellar centriole, Principal piece" "HPA038980: " "unprognostic (1.03e-2)" "unprognostic (3.21e-2)" "unprognostic (3.61e-2)" "unprognostic (6.39e-2)" "unprognostic (7.26e-3)" "unprognostic (1.90e-1)" "unprognostic (1.03e-1)" "unprognostic (1.23e-2)" "unprognostic (1.56e-1)" "unprognostic (1.42e-1)" "potential prognostic favorable (2.16e-9)" "unprognostic (5.63e-3)" "unprognostic (5.21e-2)" "unprognostic (8.98e-2)" "unprognostic (2.98e-2)" "unprognostic (1.28e-1)" "unprognostic (1.08e-1)" "unprognostic (2.54e-2)" "unprognostic (1.68e-1)" "unprognostic (3.70e-3)" "potential prognostic unfavorable (3.98e-5)" "unprognostic (1.70e-3)" "unprognostic (5.05e-2)" "unprognostic (5.84e-2)" "unprognostic (2.14e-3)" "unprognostic (5.64e-2)" "unprognostic (1.18e-1)" "unprognostic (1.83e-1)" "unprognostic (1.65e-1)" "unprognostic (7.83e-3)" "unprognostic (3.03e-1)" WDR12 "FLJ10881, YTM1" ENSG00000138442 "WD repeat domain 12" Q9GZL7 2 202874261-203014798 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Adipocytes: 161.5;Cardiomyocytes: 397.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036389 Uncertain Approved "Nucleoli,Plasma membrane,Cytosol" NA NA 9000 "Cluster 13: Non-specific - Mitochondria" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 35 "Plasma membrane, Cytosol" Nucleoli "HPA036389: " "unprognostic (2.63e-1)" "unprognostic (1.17e-2)" "unprognostic (9.31e-2)" "unprognostic (2.40e-1)" "unprognostic (1.01e-1)" "unprognostic (5.63e-2)" "unprognostic (2.81e-2)" "unprognostic (1.45e-3)" "unprognostic (1.96e-2)" "unprognostic (3.13e-2)" "unprognostic (2.70e-3)" "unprognostic (1.16e-1)" "unprognostic (1.90e-1)" "validated prognostic unfavorable (7.51e-7)" "validated prognostic unfavorable (8.28e-4)" "unprognostic (1.22e-1)" "unprognostic (1.54e-1)" "unprognostic (1.51e-1)" "unprognostic (5.23e-2)" "unprognostic (3.22e-1)" "unprognostic (2.45e-1)" "potential prognostic unfavorable (6.79e-4)" "unprognostic (1.89e-1)" "unprognostic (6.69e-2)" "unprognostic (1.31e-3)" "unprognostic (8.80e-3)" "unprognostic (8.81e-2)" "unprognostic (1.10e-1)" "unprognostic (2.34e-1)" "unprognostic (2.95e-3)" "unprognostic (6.61e-2)" WDR13 ENSG00000101940 "WD repeat domain 13" Q9H1Z4 X 48590042-48608869 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 174.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000913 Supported Supported "Nucleoplasm,Plasma membrane,Centriolar satellite" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 70: Non-specific - Protein processing" "Cluster 51: Neurons - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 97: Non-specific - Cellular respiration" 1 Nucleoplasm "Plasma membrane, Centriolar satellite" "HPA000913: " "unprognostic (2.95e-1)" "unprognostic (3.17e-2)" "unprognostic (3.73e-2)" "unprognostic (5.84e-2)" "unprognostic (3.07e-2)" "unprognostic (1.25e-1)" "unprognostic (6.26e-2)" "potential prognostic favorable (2.69e-4)" "unprognostic (2.43e-2)" "unprognostic (2.36e-1)" "unprognostic (9.57e-2)" "unprognostic (6.87e-2)" "potential prognostic favorable (7.89e-6)" "unprognostic (4.30e-2)" "unprognostic (7.63e-2)" "unprognostic (7.91e-2)" "unprognostic (1.60e-1)" "unprognostic (2.38e-1)" "unprognostic (2.00e-1)" "unprognostic (2.66e-1)" "unprognostic (2.20e-3)" "unprognostic (1.07e-1)" "unprognostic (2.96e-1)" "unprognostic (1.00e-1)" "unprognostic (1.49e-1)" "unprognostic (1.60e-1)" "unprognostic (5.23e-1)" "unprognostic (9.25e-2)" "unprognostic (8.01e-2)" "unprognostic (2.86e-1)" "unprognostic (1.63e-1)" WDR17 ENSG00000150627 "WD repeat domain 17" Q8IZU2 4 176065841-176182818 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.8;retina: 26.4" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 127.6;Astrocytes: 229.4;Bergmann glia: 231.9;Brain excitatory neurons: 224.6;Brain inhibitory neurons: 273.1;Choroid plexus epithelial cells: 125.5;Cone photoreceptor cells: 236.0;Corticotrophs: 154.6;Ependymal cells: 151.8;Lactotrophs: 211.5;Oligodendrocyte progenitor cells: 142.2;Other brain neurons: 183.7;Retinal ganglion cells: 139.1;Rod photoreceptor cells: 236.6;Somatotrophs: 194.8;Thyrotrophs: 247.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatic stellate cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042766, HPA054501" Approved Approved "Nuclear speckles" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" "Nuclear speckles" "HPA042766: , HPA054501: " "unprognostic (3.75e-1)" "unprognostic (3.55e-1)" "unprognostic (4.91e-2)" "potential prognostic unfavorable (8.96e-4)" "potential prognostic favorable (4.40e-5)" "unprognostic (1.52e-2)" "unprognostic (5.84e-2)" "unprognostic (2.57e-2)" "unprognostic (3.10e-1)" "unprognostic (1.46e-3)" WDR18 Ipi3 ENSG00000065268 "WD repeat domain 18" Q9BV38 19 984332-998438 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 102.1;Esophageal basal cells: 114.6;Esophageal suprabasal cells: 89.8;Extravillous trophoblasts: 206.4;Migrating cytotrophoblasts: 126.3;Oocytes: 92.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050193, HPA050200" Approved Supported Nucleoplasm NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 24: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 35 Nucleoplasm "HPA050193: , HPA050200: " "unprognostic (5.40e-3)" "unprognostic (1.62e-1)" "unprognostic (7.52e-2)" "unprognostic (2.32e-1)" "unprognostic (7.35e-2)" "unprognostic (3.62e-2)" "unprognostic (1.20e-1)" "unprognostic (2.51e-2)" "unprognostic (1.53e-1)" "unprognostic (3.19e-2)" "unprognostic (3.39e-3)" "unprognostic (2.76e-1)" "unprognostic (1.42e-1)" "unprognostic (2.97e-2)" "unprognostic (5.95e-2)" "unprognostic (1.20e-3)" "unprognostic (1.12e-1)" "unprognostic (2.47e-1)" "unprognostic (1.03e-2)" "unprognostic (2.13e-1)" "unprognostic (5.85e-2)" "unprognostic (1.77e-2)" "unprognostic (2.90e-1)" "unprognostic (6.66e-3)" "unprognostic (1.53e-2)" "unprognostic (7.31e-2)" "unprognostic (8.75e-2)" "unprognostic (4.87e-2)" "unprognostic (1.25e-1)" "unprognostic (2.12e-2)" "unprognostic (2.06e-2)" WDR19 "DYF-2, FAP66, FLJ23127, IFT144, KIAA1638, NPHP13, ORF26, Oseg6, Pwdmp" ENSG00000157796 "WD repeat domain 19" Q8NEZ3 4 39182504-39285810 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Ectodermal dysplasia, Leber congenital amaurosis, Nephronophthisis, Senior-Loken syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ependymal cells: 212.7;Respiratory ciliated cells: 209.9;Somatotrophs: 184.2;Thyrotrophs: 215.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039616, HPA058847" Approved Uncertain "Nucleoplasm,Centrosome,Basal body,Cytosol,Mid piece,Principal piece" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 75: Ovary - Mixed function" "Cluster 17: Choroid plexus - Cilium" "Cluster 5: Rhabdoid - Unknown function" "Cluster 34: Ciliated cells - Cilia assembly & function" 23 "Nucleoplasm, Mid piece" "Centrosome, Basal body, Cytosol, Principal piece" "HPA039616: , HPA058847: " "unprognostic (1.80e-1)" "unprognostic (5.32e-2)" "unprognostic (2.31e-2)" "unprognostic (4.01e-2)" "unprognostic (1.62e-1)" "unprognostic (2.48e-1)" "unprognostic (1.74e-1)" "unprognostic (2.96e-2)" "unprognostic (6.82e-3)" "unprognostic (3.77e-1)" "potential prognostic favorable (4.10e-7)" "unprognostic (9.11e-3)" "unprognostic (1.30e-1)" "unprognostic (4.44e-2)" "unprognostic (2.17e-1)" "unprognostic (2.21e-1)" "unprognostic (4.92e-1)" "unprognostic (3.89e-2)" "unprognostic (1.06e-1)" "unprognostic (7.57e-2)" "unprognostic (8.73e-3)" "unprognostic (4.45e-2)" "unprognostic (1.30e-2)" "unprognostic (1.16e-1)" "unprognostic (1.11e-2)" "unprognostic (8.02e-2)" "unprognostic (9.32e-2)" "unprognostic (1.88e-1)" "unprognostic (1.06e-1)" "unprognostic (6.92e-2)" "unprognostic (1.21e-1)" WDR20 "Bun107, DMR, FLJ33659, MGC33177" ENSG00000140153 "WD repeat domain 20" Q8TBZ3 14 102139503-102224847 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 370.8;Late spermatids: 367.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 47: Testis - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 7: Non-specific - Transcription" 21 "unprognostic (9.17e-2)" "unprognostic (1.83e-1)" "unprognostic (2.51e-1)" "unprognostic (4.72e-2)" "unprognostic (1.46e-1)" "potential prognostic unfavorable (4.10e-4)" "unprognostic (2.95e-2)" "unprognostic (4.38e-3)" "unprognostic (1.25e-1)" "unprognostic (4.25e-3)" "validated prognostic favorable (1.54e-6)" "validated prognostic favorable (7.69e-4)" "unprognostic (4.07e-2)" "unprognostic (7.13e-3)" "unprognostic (6.83e-2)" "unprognostic (1.53e-1)" "unprognostic (1.62e-1)" "unprognostic (3.26e-1)" "unprognostic (1.26e-1)" "unprognostic (7.41e-3)" "unprognostic (2.75e-3)" "unprognostic (1.94e-1)" "unprognostic (4.69e-2)" "unprognostic (1.19e-2)" "unprognostic (4.98e-2)" "unprognostic (4.18e-2)" "unprognostic (1.79e-1)" "unprognostic (9.69e-3)" "unprognostic (3.06e-1)" "unprognostic (1.89e-1)" "unprognostic (1.85e-1)" WDR24 "C16orf21, DKFZp434F054, JFP7" ENSG00000127580 "WD repeat domain 24" Q96S15 16 684622-690444 "Predicted intracellular proteins" "Autophagy, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric progenitor cells: 37.2;Late primary spermatocytes: 30.5;Late spermatids: 76.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039506 Approved Supported Vesicles,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 24: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 54: Non-specific - Transcription" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 25 Vesicles Cytosol "HPA039506: " "unprognostic (2.13e-1)" "unprognostic (9.68e-2)" "unprognostic (2.60e-1)" "unprognostic (2.62e-2)" "unprognostic (7.99e-2)" "unprognostic (2.15e-1)" "unprognostic (2.08e-1)" "unprognostic (1.14e-1)" "unprognostic (1.29e-2)" "unprognostic (1.55e-1)" "potential prognostic favorable (3.43e-4)" "unprognostic (1.47e-2)" "unprognostic (1.15e-2)" "unprognostic (7.76e-2)" "unprognostic (1.50e-1)" "unprognostic (2.54e-2)" "unprognostic (9.31e-2)" "unprognostic (1.42e-1)" "unprognostic (2.09e-2)" "unprognostic (4.82e-2)" "unprognostic (9.27e-2)" "unprognostic (1.05e-2)" "unprognostic (2.46e-1)" "unprognostic (1.31e-1)" "unprognostic (2.01e-2)" "unprognostic (2.58e-2)" "unprognostic (1.14e-1)" "unprognostic (2.39e-1)" "unprognostic (2.04e-1)" "unprognostic (1.14e-2)" "unprognostic (9.90e-2)" WDR25 "C14orf67, MGC4645" ENSG00000176473 "WD repeat domain 25" Q64LD2 14 100376418-100530303 "Essential proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pancreatic acinar cells: 208.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003113 Uncertain Approved Nucleoplasm "Secreted to blood" "No annotated function" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 70: Non-specific - Protein processing" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 65: Non-specific - Unknown function" "Cluster 51: Secretory epithelial cells - Mixed function" 6 Nucleoplasm "HPA003113: " "unprognostic (1.46e-1)" "unprognostic (7.36e-2)" "potential prognostic unfavorable (2.93e-4)" "unprognostic (6.04e-3)" "unprognostic (1.43e-1)" "unprognostic (4.89e-2)" "unprognostic (2.24e-2)" "unprognostic (4.61e-2)" "unprognostic (4.65e-2)" "unprognostic (2.74e-2)" "unprognostic (3.09e-3)" "unprognostic (5.18e-2)" "unprognostic (5.97e-3)" "potential prognostic unfavorable (1.66e-4)" "unprognostic (3.78e-2)" "unprognostic (2.44e-1)" "unprognostic (2.83e-1)" "unprognostic (5.92e-2)" "unprognostic (1.75e-1)" "unprognostic (2.73e-3)" "potential prognostic unfavorable (5.24e-4)" "unprognostic (6.79e-3)" "unprognostic (1.03e-1)" "unprognostic (1.37e-1)" "unprognostic (9.19e-3)" "unprognostic (2.32e-1)" "unprognostic (3.83e-1)" "unprognostic (2.44e-3)" "unprognostic (1.52e-1)" "unprognostic (1.46e-1)" "unprognostic (1.37e-2)" WDR26 "FLJ21016, GID7" ENSG00000162923 "WD repeat domain 26" Q9H7D7 1 224385146-224437033 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 880.7;Neutrophils: 1159.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028538, HPA028539, HPA061094" Enhanced Enhanced Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 58 "Nucleoplasm, Cytosol" Mitochondria "HPA028538: , HPA028539: , HPA061094: " "unprognostic (1.18e-1)" "unprognostic (2.39e-2)" "unprognostic (2.22e-1)" "unprognostic (1.23e-2)" "unprognostic (7.97e-2)" "unprognostic (1.00e-1)" "unprognostic (4.05e-2)" "unprognostic (5.31e-2)" "unprognostic (4.23e-1)" "unprognostic (4.17e-2)" "unprognostic (1.40e-2)" "unprognostic (1.92e-1)" "unprognostic (6.08e-3)" "unprognostic (7.13e-2)" "unprognostic (4.84e-2)" "unprognostic (1.06e-1)" "unprognostic (2.43e-2)" "unprognostic (6.50e-2)" "unprognostic (2.40e-1)" "unprognostic (1.42e-1)" "unprognostic (2.18e-2)" "unprognostic (4.32e-2)" "unprognostic (9.64e-3)" "unprognostic (2.09e-1)" "unprognostic (3.71e-2)" "unprognostic (1.30e-1)" "unprognostic (6.35e-2)" "unprognostic (8.94e-2)" "unprognostic (1.59e-1)" "unprognostic (9.73e-2)" "unprognostic (2.19e-1)" WDR27 MGC43690 ENSG00000184465 "WD repeat domain 27" A2RRH5 6 169457212-169702067 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Distal convoluted tubule cells: 138.3;Loop of henle epithelial cells: 104.4;Papillary tip epithelial cells: 60.9;Podocytes: 90.6;Proximal tubule cells: 106.5;Renal collecting duct intercalated cells: 71.0;Renal collecting duct principal cells: 90.8;Renal connecting tubule cells: 113.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA037497, HPA037498" Uncertain Enhanced Nucleoplasm NA NA "Cluster 75: Ovary - Mixed function" "Cluster 17: Choroid plexus - Cilium" "Cluster 28: Non-specific - Nuclear processes" "Cluster 105: Non-specific - Mixed function" 1 Nucleoplasm "HPA037497: , HPA037498: " "unprognostic (9.53e-2)" "unprognostic (1.48e-1)" "unprognostic (4.73e-1)" "unprognostic (5.27e-2)" "unprognostic (2.34e-2)" "unprognostic (1.90e-3)" "unprognostic (9.93e-2)" "unprognostic (9.14e-2)" "unprognostic (4.75e-2)" "potential prognostic unfavorable (2.10e-4)" "unprognostic (3.36e-2)" "unprognostic (8.78e-3)" "unprognostic (3.33e-1)" "unprognostic (2.63e-2)" "unprognostic (1.47e-1)" "unprognostic (1.17e-1)" "unprognostic (7.10e-2)" "unprognostic (9.76e-2)" "unprognostic (2.56e-3)" "unprognostic (3.91e-2)" "unprognostic (4.34e-3)" "potential prognostic unfavorable (1.58e-5)" "unprognostic (2.27e-2)" "unprognostic (1.22e-1)" "potential prognostic unfavorable (3.39e-4)" "unprognostic (1.37e-1)" "unprognostic (2.60e-1)" "unprognostic (1.81e-1)" "unprognostic (2.47e-3)" WDR3 "DIP2, FLJ12796, UTP12" ENSG00000065183 "WD repeat domain 3" Q9UNX4 1 117929720-117966543 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 74.7;Early primary spermatocytes: 78.0;Parietal cells: 123.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027509, HPA054354, HPA072915" Enhanced Nucleoplasm,Nucleoli No No "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 23: Choroid plexus - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 33 Nucleoli Nucleoplasm "HPA027509: , HPA054354: , HPA072915: " "unprognostic (3.13e-2)" "unprognostic (2.21e-1)" "unprognostic (3.00e-1)" "potential prognostic unfavorable (2.62e-4)" "unprognostic (2.84e-2)" "unprognostic (7.77e-2)" "unprognostic (2.15e-2)" "unprognostic (4.39e-3)" "unprognostic (1.12e-1)" "potential prognostic unfavorable (2.99e-4)" "potential prognostic favorable (4.65e-6)" "unprognostic (1.61e-2)" "unprognostic (2.65e-2)" "potential prognostic unfavorable (3.93e-4)" "unprognostic (6.58e-3)" "unprognostic (2.54e-3)" "potential prognostic unfavorable (3.62e-4)" "unprognostic (2.31e-1)" "unprognostic (6.55e-2)" "unprognostic (1.50e-1)" "unprognostic (3.69e-1)" "potential prognostic unfavorable (8.81e-4)" "unprognostic (2.02e-2)" "unprognostic (1.69e-2)" "potential prognostic favorable (1.73e-4)" "unprognostic (5.28e-2)" "unprognostic (2.45e-2)" "unprognostic (1.16e-1)" "unprognostic (2.15e-1)" "unprognostic (9.87e-3)" "unprognostic (1.79e-1)" WDR31 FLJ35921 ENSG00000148225 "WD repeat domain 31" Q8NA23 9 113313222-113340298 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 10.4;retina: 16.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 76.6;Early primary spermatocytes: 67.1;Respiratory ciliated cells: 67.7;Rod photoreceptor cells: 118.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.5" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019340, HPA019347" Approved Approved "Nuclear bodies,Cytosol" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 79: Photoreceptor cells - Phototransduction" Cytosol "Nuclear bodies" "HPA019340: , HPA019347: " "unprognostic (2.99e-3)" "unprognostic (1.41e-1)" "unprognostic (5.69e-2)" "unprognostic (1.63e-1)" "unprognostic (1.31e-1)" "unprognostic (1.15e-1)" "unprognostic (1.29e-1)" "unprognostic (1.55e-1)" "unprognostic (7.71e-2)" "unprognostic (3.27e-2)" "validated prognostic favorable (3.81e-8)" "validated prognostic favorable (2.28e-6)" "potential prognostic favorable (2.14e-4)" "unprognostic (9.67e-2)" "unprognostic (2.52e-1)" "unprognostic (4.55e-3)" "unprognostic (1.31e-2)" "unprognostic (2.10e-1)" "unprognostic (2.00e-2)" "unprognostic (8.08e-2)" "unprognostic (1.58e-1)" "unprognostic (1.89e-1)" "unprognostic (5.77e-2)" "unprognostic (4.20e-1)" "unprognostic (1.05e-1)" "unprognostic (1.10e-1)" "unprognostic (2.25e-1)" "unprognostic (1.02e-1)" "potential prognostic favorable (6.22e-4)" WDR33 "FLJ11294, NET14, WDC146" ENSG00000136709 "WD repeat domain 33" Q9C0J8 2 127701027-127811187 "Essential proteins, Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pancreas - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026897, HPA046527" Supported Enhanced "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 64: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 7: Non-specific - Transcription" 30 "Nucleoplasm, Nucleoli fibrillar center" "HPA026897: , HPA046527: " "unprognostic (2.07e-1)" "unprognostic (1.16e-1)" "unprognostic (1.49e-1)" "unprognostic (6.12e-2)" "unprognostic (1.77e-1)" "unprognostic (1.88e-1)" "unprognostic (8.05e-2)" "unprognostic (4.52e-3)" "unprognostic (3.00e-1)" "unprognostic (1.06e-2)" "validated prognostic favorable (6.94e-5)" "validated prognostic favorable (1.28e-4)" "unprognostic (5.08e-2)" "unprognostic (8.30e-3)" "unprognostic (9.87e-2)" "unprognostic (2.32e-1)" "unprognostic (2.98e-1)" "unprognostic (8.20e-2)" "unprognostic (2.22e-1)" "unprognostic (3.55e-1)" "unprognostic (2.93e-1)" "unprognostic (7.58e-2)" "unprognostic (1.19e-2)" "unprognostic (2.49e-2)" "unprognostic (5.82e-2)" "unprognostic (1.53e-1)" "unprognostic (2.65e-2)" "unprognostic (8.19e-2)" "unprognostic (2.90e-1)" "unprognostic (2.07e-1)" "unprognostic (1.35e-1)" WDR35 "FAP118, IFT121, IFTA1, KIAA1336, MGC33196" ENSG00000118965 "WD repeat domain 35" Q9P2L0 2 19910263-19990105 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 215.0;Ependymal cells: 189.6;Lactotrophs: 143.8;Somatotrophs: 144.7;Thyrotrophs: 156.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "basophil: 2.9" "Lineage enriched" "Detected in single" 5 "granulocytes: 2.9" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044147 Approved NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 34: Ciliated cells - Cilia assembly & function" 12 "HPA044147: " "unprognostic (2.25e-1)" "unprognostic (1.87e-1)" "unprognostic (1.79e-1)" "unprognostic (1.49e-2)" "unprognostic (3.79e-2)" "unprognostic (5.21e-1)" "unprognostic (5.33e-2)" "unprognostic (3.75e-1)" "unprognostic (1.96e-1)" "unprognostic (2.55e-2)" "potential prognostic favorable (2.27e-6)" "unprognostic (9.28e-2)" "unprognostic (5.35e-2)" "potential prognostic unfavorable (9.32e-4)" "unprognostic (3.05e-3)" "unprognostic (7.59e-2)" "unprognostic (2.79e-1)" "unprognostic (2.47e-1)" "unprognostic (3.93e-1)" "unprognostic (2.37e-1)" "unprognostic (4.57e-1)" "unprognostic (7.45e-2)" "unprognostic (2.54e-1)" "unprognostic (9.36e-2)" "unprognostic (1.67e-1)" "unprognostic (1.05e-3)" "unprognostic (4.32e-1)" "unprognostic (7.05e-3)" "unprognostic (3.45e-1)" "unprognostic (2.37e-2)" "unprognostic (5.22e-2)" WDR36 "GLC1G, TA-WDRP, UTP21" ENSG00000134987 "WD repeat domain 36" 5 111092321-111130502 "Essential proteins, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037796, HPA037797" Supported Supported Nucleoli NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 31: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 25 Nucleoli "HPA037796: , HPA037797: " "unprognostic (6.42e-2)" "unprognostic (1.35e-1)" "unprognostic (2.15e-1)" "unprognostic (2.84e-2)" "unprognostic (3.35e-1)" "unprognostic (1.59e-1)" "unprognostic (2.22e-1)" "unprognostic (1.11e-2)" "unprognostic (4.06e-2)" "unprognostic (4.74e-3)" "unprognostic (1.08e-3)" "unprognostic (9.75e-2)" "unprognostic (1.26e-2)" "unprognostic (3.97e-3)" "unprognostic (1.84e-1)" "unprognostic (2.13e-3)" "unprognostic (4.19e-2)" "unprognostic (9.07e-2)" "unprognostic (3.77e-1)" "unprognostic (2.63e-3)" "unprognostic (1.41e-2)" "unprognostic (5.60e-2)" "unprognostic (8.31e-2)" "unprognostic (1.22e-1)" "unprognostic (7.01e-3)" "unprognostic (3.57e-1)" "unprognostic (1.82e-1)" "unprognostic (2.74e-1)" "unprognostic (2.95e-1)" "potential prognostic unfavorable (6.55e-4)" "unprognostic (3.16e-1)" WDR37 KIAA0982 ENSG00000047056 "WD repeat domain 37" Q9Y2I8 10 1049538-1160991 "Disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 373.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037376, HPA037565" Enhanced Approved "Intermediate filaments" No No "Cluster 15: NK-cells - Unknown function" "Cluster 67: Testis - Mixed function" "Cluster 14: Neurons - Synaptic function" "Cluster 52: Non-specific - Mitochondria" "Cluster 55: Myocytes - Oxidative muscle function" 11 "Intermediate filaments" "HPA037376: , HPA037565: " "unprognostic (1.29e-1)" "unprognostic (3.04e-2)" "unprognostic (3.88e-2)" "unprognostic (3.81e-2)" "unprognostic (5.82e-2)" "unprognostic (2.12e-1)" "unprognostic (3.19e-1)" "potential prognostic favorable (1.27e-5)" "potential prognostic favorable (2.10e-4)" "unprognostic (3.03e-1)" "potential prognostic favorable (4.34e-4)" "unprognostic (1.85e-2)" "potential prognostic favorable (1.72e-4)" "potential prognostic unfavorable (7.64e-4)" "unprognostic (2.47e-1)" "unprognostic (2.12e-2)" "unprognostic (2.30e-1)" "unprognostic (2.53e-1)" "unprognostic (3.04e-1)" "unprognostic (5.65e-2)" "unprognostic (2.36e-2)" "potential prognostic favorable (1.59e-4)" "unprognostic (8.78e-2)" "unprognostic (2.99e-1)" "unprognostic (8.77e-3)" "unprognostic (1.66e-1)" "unprognostic (2.46e-1)" "unprognostic (8.90e-2)" "unprognostic (1.56e-1)" "potential prognostic unfavorable (5.48e-7)" "unprognostic (1.86e-1)" WDR38 ENSG00000136918 "WD repeat domain 38" Q5JTN6 9 124853417-124857890 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "choroid plexus: 42.5;fallopian tube: 73.1" "Group enriched" "Detected in some" 5 "Endometrial ciliated cells: 99.7;Epididymal efferent duct ciliated cells: 162.8;Fallopian tube ciliated cells: 222.5;Late spermatids: 175.3;Respiratory ciliated cells: 283.7" "Cell type enriched" "Detected in some" 8 "ependymal cell: 49.5" "Group enriched" "Detected in some" 4 "Glioblastoma Multiforme (TCGA): 5.1;Lung Adenocarcinoma (TCGA): 3.8;Ovary Serous Cystadenocarcinoma (TCGA): 5.3;Uterine Corpus Endometrial Carcinoma (TCGA): 13.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA056607 Approved Vesicles NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" Vesicles "HPA056607: " "unprognostic (1.06e-1)" "potential prognostic favorable (3.07e-5)" "unprognostic (5.83e-2)" "unprognostic (5.35e-2)" "unprognostic (2.12e-1)" "unprognostic (9.69e-2)" "unprognostic (2.10e-1)" "unprognostic (3.07e-1)" "unprognostic (3.06e-3)" "unprognostic (4.76e-3)" WDR4 "TRM82, TRMT82, Wuho" ENSG00000160193 "WD repeat domain 4" P57081 21 42843094-42879568 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, tRNA processing" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 74.0;Oocytes: 59.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017381 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 37: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 51: Secretory epithelial cells - Mixed function" 12 Nucleoplasm Cytosol "HPA017381: " "unprognostic (1.50e-1)" "unprognostic (2.31e-2)" "unprognostic (3.23e-1)" "unprognostic (2.92e-2)" "unprognostic (1.99e-1)" "unprognostic (2.36e-2)" "unprognostic (8.97e-2)" "unprognostic (5.37e-3)" "unprognostic (3.58e-2)" "unprognostic (1.58e-1)" "unprognostic (1.13e-1)" "unprognostic (2.18e-1)" "unprognostic (2.23e-1)" "validated prognostic unfavorable (2.19e-6)" "validated prognostic unfavorable (3.69e-5)" "potential prognostic unfavorable (9.95e-6)" "unprognostic (6.37e-2)" "unprognostic (1.49e-1)" "unprognostic (2.42e-1)" "unprognostic (3.35e-2)" "unprognostic (1.29e-1)" "unprognostic (8.99e-2)" "unprognostic (3.24e-2)" "unprognostic (2.41e-3)" "unprognostic (2.36e-3)" "unprognostic (6.49e-3)" "unprognostic (2.76e-2)" "unprognostic (1.79e-2)" "unprognostic (1.95e-1)" "unprognostic (2.21e-2)" "unprognostic (2.86e-2)" WDR41 FLJ10904 ENSG00000164253 "WD repeat domain 41" Q9HAD4 5 77425970-77620611 "Predicted intracellular proteins" Autophagy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 338.2;Late primary spermatocytes: 232.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043124 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 89: Adipocytes - Lipid metabolism" 8 Nucleoplasm "Golgi apparatus, Cytosol" "HPA043124: " "unprognostic (4.58e-1)" "unprognostic (6.11e-2)" "unprognostic (5.62e-2)" "unprognostic (1.16e-2)" "unprognostic (1.48e-1)" "unprognostic (4.09e-1)" "unprognostic (3.50e-2)" "unprognostic (3.43e-2)" "unprognostic (3.12e-3)" "unprognostic (4.42e-3)" "potential prognostic favorable (7.60e-5)" "unprognostic (2.64e-1)" "unprognostic (1.10e-1)" "potential prognostic unfavorable (2.27e-5)" "unprognostic (9.27e-2)" "unprognostic (2.37e-2)" "unprognostic (4.13e-2)" "unprognostic (3.87e-2)" "unprognostic (3.67e-1)" "unprognostic (3.57e-2)" "unprognostic (3.40e-2)" "unprognostic (4.56e-3)" "unprognostic (3.19e-2)" "unprognostic (2.61e-2)" "unprognostic (1.02e-1)" "unprognostic (2.11e-1)" "unprognostic (3.08e-1)" "unprognostic (3.87e-2)" "unprognostic (1.90e-1)" "unprognostic (1.05e-1)" "unprognostic (2.23e-1)" WDR43 "KIAA0007, NET12, UTP5" ENSG00000163811 "WD repeat domain 43" Q15061 2 28894667-28948219 "Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing, Transcription, Transcription regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 296.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044733 Uncertain NA NA 8100 "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Ribosome" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 17: Non-specific - RNA processing" 28 "HPA044733: " "unprognostic (5.86e-2)" "unprognostic (2.11e-1)" "unprognostic (4.27e-2)" "potential prognostic unfavorable (7.19e-4)" "unprognostic (1.29e-1)" "unprognostic (4.42e-2)" "unprognostic (1.92e-1)" "unprognostic (5.97e-2)" "unprognostic (1.22e-2)" "unprognostic (2.43e-3)" "unprognostic (1.06e-3)" "unprognostic (4.33e-2)" "unprognostic (1.14e-2)" "validated prognostic unfavorable (3.16e-5)" "validated prognostic unfavorable (1.04e-4)" "unprognostic (1.20e-2)" "potential prognostic unfavorable (6.25e-5)" "unprognostic (6.22e-2)" "unprognostic (7.93e-3)" "unprognostic (1.75e-1)" "unprognostic (1.78e-1)" "unprognostic (1.49e-3)" "unprognostic (4.58e-3)" "unprognostic (2.37e-2)" "unprognostic (7.11e-3)" "unprognostic (1.40e-1)" "unprognostic (4.38e-2)" "unprognostic (3.30e-1)" "unprognostic (2.49e-1)" "unprognostic (1.19e-2)" "unprognostic (2.26e-1)" WDR44 "DKFZp686L20145, RAB11BP, RPH11, SYM-4" ENSG00000131725 "WD repeat domain 44" Q5JSH3 X 118346073-118449961 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038084, HPA046719" Approved Supported "Golgi apparatus" NA NA 2600000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 21 "Golgi apparatus" "HPA038084: , HPA046719: " "unprognostic (1.19e-2)" "unprognostic (1.74e-2)" "unprognostic (9.71e-2)" "unprognostic (2.73e-1)" "unprognostic (9.28e-2)" "unprognostic (1.46e-2)" "unprognostic (2.05e-1)" "unprognostic (1.42e-1)" "unprognostic (6.51e-2)" "unprognostic (2.53e-1)" "potential prognostic favorable (8.10e-6)" "unprognostic (2.12e-1)" "unprognostic (1.96e-2)" "unprognostic (1.05e-1)" "unprognostic (1.11e-2)" "unprognostic (1.93e-1)" "unprognostic (1.58e-3)" "unprognostic (1.32e-2)" "unprognostic (3.43e-2)" "unprognostic (3.62e-2)" "unprognostic (8.91e-3)" "potential prognostic unfavorable (8.09e-4)" "unprognostic (1.38e-2)" "unprognostic (1.77e-1)" "unprognostic (1.15e-1)" "unprognostic (2.49e-1)" "unprognostic (1.57e-1)" "unprognostic (2.70e-1)" "unprognostic (3.92e-1)" "unprognostic (1.36e-1)" "unprognostic (2.68e-1)" WDR45 "JM5, NBIA5, WDRX1, WIPI4" ENSG00000196998 "WD repeat domain 45" Q9Y484 X 49074433-49101170 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Autophagy "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Epididymal principal cells: 364.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027562 Uncertain NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 70: Non-specific - Protein processing" "Cluster 19: Astrocytes - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 8 "HPA027562: " "unprognostic (3.36e-2)" "unprognostic (1.38e-1)" "unprognostic (2.49e-1)" "unprognostic (2.86e-2)" "unprognostic (2.36e-2)" "unprognostic (1.82e-1)" "unprognostic (1.72e-1)" "potential prognostic favorable (6.23e-4)" "unprognostic (3.85e-3)" "unprognostic (1.23e-1)" "potential prognostic favorable (9.64e-4)" "unprognostic (1.49e-2)" "unprognostic (2.76e-2)" "unprognostic (3.18e-2)" "unprognostic (8.44e-2)" "unprognostic (1.24e-1)" "unprognostic (6.96e-2)" "unprognostic (7.21e-2)" "unprognostic (7.46e-2)" "unprognostic (8.68e-2)" "unprognostic (3.40e-2)" "unprognostic (2.42e-2)" "unprognostic (3.47e-1)" "unprognostic (3.80e-1)" "unprognostic (9.20e-2)" "unprognostic (1.44e-1)" "unprognostic (1.83e-2)" "unprognostic (1.72e-1)" "unprognostic (2.48e-1)" "unprognostic (7.41e-2)" "unprognostic (1.62e-1)" WDR45B "WDR45L, WIPI3" ENSG00000141580 "WD repeat domain 45B" Q5MNZ6 17 82614562-82648553 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Autophagy "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 497.7;Late spermatids: 710.5;Mast cells: 399.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Spleen - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017886 Uncertain "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 4 "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA017886: " "unprognostic (2.39e-1)" "unprognostic (1.41e-1)" "unprognostic (1.12e-2)" "unprognostic (4.47e-2)" "unprognostic (1.59e-1)" "unprognostic (1.99e-2)" "unprognostic (4.37e-1)" "unprognostic (2.52e-1)" "unprognostic (7.99e-2)" "potential prognostic favorable (1.31e-6)" "unprognostic (1.03e-1)" "unprognostic (2.91e-1)" "potential prognostic unfavorable (3.99e-4)" "unprognostic (3.23e-2)" "unprognostic (1.46e-1)" "unprognostic (2.18e-1)" "potential prognostic favorable (7.57e-4)" "unprognostic (1.16e-1)" "unprognostic (1.83e-2)" "unprognostic (2.83e-1)" "unprognostic (1.42e-1)" "unprognostic (5.30e-2)" "unprognostic (7.09e-3)" "unprognostic (4.75e-1)" "unprognostic (1.25e-1)" "unprognostic (1.25e-1)" "unprognostic (2.46e-1)" "unprognostic (6.39e-2)" "unprognostic (8.30e-2)" WDR46 "BING4, C6orf11, UTP7" ENSG00000227057 "WD repeat domain 46" O15213 6 33279108-33289247 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 72.2;Oocytes: 50.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043004, HPA055425" Uncertain Supported Nucleoli NA NA 11000 "Cluster 33: Non-specific - ATP binding" "Cluster 24: Non-specific - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 12 Nucleoli "HPA043004: , HPA055425: " "unprognostic (1.53e-1)" "unprognostic (9.23e-2)" "unprognostic (2.27e-1)" "unprognostic (7.78e-2)" "unprognostic (1.79e-1)" "unprognostic (1.36e-1)" "unprognostic (1.67e-2)" "unprognostic (5.39e-2)" "unprognostic (3.29e-2)" "unprognostic (9.94e-2)" "unprognostic (1.74e-2)" "unprognostic (2.68e-1)" "unprognostic (8.97e-2)" "potential prognostic unfavorable (3.03e-4)" "unprognostic (1.59e-3)" "unprognostic (3.02e-1)" "unprognostic (1.98e-1)" "unprognostic (3.35e-2)" "unprognostic (2.77e-3)" "unprognostic (2.96e-1)" "unprognostic (2.67e-1)" "unprognostic (4.44e-2)" "unprognostic (7.96e-2)" "unprognostic (1.07e-1)" "unprognostic (1.16e-2)" "unprognostic (3.76e-1)" "unprognostic (2.62e-1)" "unprognostic (1.41e-1)" "unprognostic (1.84e-1)" "unprognostic (1.34e-1)" "unprognostic (3.81e-1)" WDR47 KIAA0893 ENSG00000085433 "WD repeat domain 47" O94967 1 108970214-109042113 "Predicted intracellular proteins, Transporters" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 41.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 219.4;Rod photoreceptor cells: 129.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Skin - Keratinocyte (other), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027287, HPA027289" Approved Approved "Actin filaments,Primary cilium" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 37: Non-specific - mRNA processing" "Cluster 20: Non-specific - Transcription regulation" 4 "Actin filaments, Primary cilium" "HPA027287: , HPA027289: " "unprognostic (1.86e-2)" "unprognostic (7.54e-2)" "unprognostic (1.28e-1)" "unprognostic (3.23e-1)" "unprognostic (3.31e-1)" "unprognostic (7.78e-3)" "unprognostic (3.14e-1)" "unprognostic (9.09e-3)" "potential prognostic favorable (7.69e-4)" "unprognostic (2.11e-3)" "validated prognostic favorable (3.75e-6)" "validated prognostic favorable (6.49e-4)" "unprognostic (8.91e-2)" "unprognostic (9.75e-3)" "unprognostic (1.55e-1)" "unprognostic (1.20e-2)" "unprognostic (4.72e-3)" "unprognostic (1.80e-2)" "unprognostic (1.04e-1)" "unprognostic (2.09e-2)" "unprognostic (7.72e-2)" "unprognostic (5.21e-2)" "unprognostic (2.10e-1)" "unprognostic (1.32e-1)" "unprognostic (3.12e-2)" "unprognostic (2.19e-2)" "unprognostic (1.61e-1)" "unprognostic (5.74e-2)" "unprognostic (3.81e-2)" "unprognostic (1.06e-2)" "unprognostic (4.92e-2)" WDR48 "Bun62, KIAA1449, P80, SPG60" ENSG00000114742 "WD repeat domain 48" Q8TAF3 3 39052013-39096671 "Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction, Ubl conjugation pathway" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038421, HPA058015" Approved Supported Vesicles NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 38 Vesicles "HPA038421: , HPA058015: " "unprognostic (3.02e-2)" "unprognostic (2.04e-1)" "unprognostic (3.12e-1)" "unprognostic (8.45e-2)" "unprognostic (7.59e-2)" "unprognostic (6.37e-2)" "unprognostic (2.06e-1)" "unprognostic (2.82e-3)" "unprognostic (1.19e-3)" "unprognostic (8.15e-3)" "potential prognostic favorable (3.42e-6)" "unprognostic (2.28e-2)" "unprognostic (1.73e-2)" "unprognostic (3.98e-3)" "unprognostic (6.07e-2)" "unprognostic (3.43e-2)" "unprognostic (2.27e-1)" "unprognostic (2.33e-1)" "unprognostic (3.85e-1)" "unprognostic (4.87e-2)" "unprognostic (2.53e-2)" "unprognostic (2.21e-1)" "unprognostic (2.34e-1)" "unprognostic (3.50e-2)" "potential prognostic favorable (5.36e-5)" "unprognostic (1.51e-1)" "unprognostic (1.67e-1)" "unprognostic (4.62e-1)" "unprognostic (2.09e-1)" "unprognostic (2.77e-1)" "unprognostic (2.10e-1)" WDR49 FLJ33620 ENSG00000174776 "WD repeat domain 49" Q8IV35 3 167478684-167653983 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 8.8;fallopian tube: 8.5;intestine: 4.2" "Cell type enhanced" "Detected in many" "Astrocytes: 304.6;Bergmann glia: 618.4;Choroid plexus epithelial cells: 747.4;Endometrial ciliated cells: 463.8;Ependymal cells: 1533.8;Epididymal efferent duct ciliated cells: 226.6;Fallopian tube ciliated cells: 355.0;Podocytes: 405.5;Respiratory ciliated cells: 1021.4;Respiratory deuterosomal cells: 269.5" "Group enriched" "Detected in all" 48 "astrocyte: 615.9;Bergmann glia: 657.4;choroid plexus epithelial cell: 560.5;ependymal cell: 1727.6" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 2.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "classical monocyte: 2.7;myeloid DC: 2.2;plasmacytoid DC: 2.9" "Group enriched" "Detected in many" 24 "dendritic cells: 2.9;monocytes: 2.7" "Cancer enriched" "Detected in single" 7 "Leukemia: 2.1" "Kidney - Podocytes, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Region enhanced" "Detected in many" "midbrain: 12.1" "HPA036225, HPA036226" Uncertain Approved "Nucleoplasm,Nuclear bodies,Mitotic spindle,Primary cilium,Primary cilium tip,Primary cilium transition zone,Basal body,Cytosol" Yes NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 34: Ciliated cells - Cilia assembly & function" 1 "Nucleoplasm, Nuclear bodies" "Mitotic spindle, Primary cilium, Primary cilium tip, Primary cilium transition zone, Basal body, Cytosol" "HPA036225: , HPA036226: " "unprognostic (1.63e-1)" "unprognostic (1.72e-3)" "unprognostic (3.20e-1)" "unprognostic (9.21e-3)" "unprognostic (1.29e-2)" "unprognostic (1.18e-1)" "unprognostic (2.12e-1)" "unprognostic (1.96e-1)" "unprognostic (1.78e-2)" "unprognostic (2.63e-3)" "unprognostic (2.97e-1)" WDR5 "CFAP89, SWD3" ENSG00000196363 "WD repeat domain 5" P61964 9 134135365-134159968 "Essential proteins, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 145.9;Late primary spermatocytes: 211.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047182, HPA076612" Enhanced "Nucleoplasm,Principal piece" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 67: Testis - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 282 Nucleoplasm "Principal piece" "HPA047182: , HPA076612: " "unprognostic (3.13e-2)" "unprognostic (2.32e-2)" "unprognostic (7.15e-2)" "unprognostic (2.73e-3)" "unprognostic (6.57e-2)" "unprognostic (2.80e-2)" "unprognostic (4.20e-1)" "unprognostic (2.32e-3)" "unprognostic (3.14e-1)" "unprognostic (3.29e-1)" "unprognostic (5.04e-3)" "unprognostic (6.10e-3)" "unprognostic (9.17e-2)" "unprognostic (1.24e-2)" "unprognostic (5.27e-3)" "unprognostic (4.08e-3)" "unprognostic (3.76e-2)" "unprognostic (1.52e-1)" "unprognostic (7.81e-3)" "unprognostic (8.98e-2)" "unprognostic (7.53e-2)" "unprognostic (4.39e-3)" "unprognostic (2.57e-1)" "unprognostic (1.31e-3)" "unprognostic (1.40e-1)" "unprognostic (7.01e-2)" "unprognostic (2.76e-1)" "unprognostic (5.00e-2)" "unprognostic (5.04e-1)" "unprognostic (9.50e-2)" "unprognostic (3.26e-3)" WDR53 "MGC12928, MGC64882" ENSG00000185798 "WD repeat domain 53" Q7Z5U6 3 196554177-196568674 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "testis: 70.3" "Group enriched" "Detected in many" 6 "Early spermatids: 298.5;Late primary spermatocytes: 389.2;Late spermatids: 147.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016420 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 39: Testis - Nuclear processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 3 "Plasma membrane, Cytosol" "HPA016420: " "unprognostic (3.30e-2)" "unprognostic (9.37e-3)" "unprognostic (2.76e-2)" "unprognostic (8.30e-3)" "unprognostic (1.19e-1)" "unprognostic (6.85e-2)" "unprognostic (1.21e-1)" "unprognostic (2.94e-1)" "unprognostic (1.43e-1)" "unprognostic (3.64e-3)" "unprognostic (1.73e-1)" "unprognostic (2.87e-1)" "unprognostic (1.82e-1)" "potential prognostic unfavorable (1.66e-7)" "unprognostic (3.10e-2)" "unprognostic (1.05e-2)" "unprognostic (1.03e-2)" "unprognostic (2.32e-2)" "unprognostic (1.12e-1)" "unprognostic (3.69e-1)" "unprognostic (2.08e-2)" "unprognostic (1.63e-2)" "unprognostic (6.24e-2)" "potential prognostic unfavorable (4.86e-5)" "unprognostic (3.61e-2)" "unprognostic (3.78e-1)" "unprognostic (3.02e-3)" "unprognostic (6.72e-2)" "unprognostic (2.89e-1)" "unprognostic (2.19e-1)" "unprognostic (1.09e-1)" WDR54 FLJ12953 ENSG00000005448 "WD repeat domain 54" Q9H977 2 74421678-74425755 "Predicted intracellular proteins" Fertilization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "fallopian tube: 66.0" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 212.6;Epididymal efferent duct ciliated cells: 262.7;Fallopian tube ciliated cells: 496.9;Late primary spermatocytes: 195.0;Late spermatids: 189.1;Respiratory ciliated cells: 452.2" "Cell type enhanced" "Detected in all" "ependymal cell: 54.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Liver - Vascular endothelial cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043257, HPA053558" Enhanced Approved "Nucleoli,Golgi apparatus,Vesicles,Primary cilium tip,Centriolar satellite,Cytosol,Acrosome,Flagellar centriole,Mid piece,Principal piece" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 107: Ciliated cells - Cilia assembly & function" 4 "Golgi apparatus, Vesicles, Acrosome" "Nucleoli, Primary cilium tip, Centriolar satellite, Cytosol, Flagellar centriole, Mid piece, Principal piece" "HPA043257: , HPA053558: " "potential prognostic unfavorable (2.27e-4)" "unprognostic (4.49e-2)" "unprognostic (1.96e-1)" "unprognostic (9.22e-2)" "unprognostic (4.28e-1)" "unprognostic (9.17e-2)" "unprognostic (4.43e-2)" "unprognostic (1.49e-1)" "unprognostic (1.01e-3)" "unprognostic (1.56e-1)" "potential prognostic favorable (1.52e-5)" "unprognostic (2.29e-2)" "unprognostic (3.19e-2)" "unprognostic (2.28e-2)" "unprognostic (7.44e-2)" "unprognostic (2.86e-1)" "unprognostic (4.97e-2)" "unprognostic (5.44e-2)" "unprognostic (1.83e-1)" "unprognostic (2.34e-2)" "unprognostic (1.35e-1)" "unprognostic (1.77e-3)" "unprognostic (8.74e-2)" "unprognostic (7.37e-2)" "unprognostic (4.27e-2)" "unprognostic (9.78e-2)" "unprognostic (2.61e-2)" "unprognostic (7.27e-2)" "unprognostic (4.99e-1)" "unprognostic (2.46e-1)" "unprognostic (2.49e-2)" WDR55 "FLJ20195, FLJ21702" ENSG00000120314 "WD repeat domain 55" Q9H6Y2 5 140664868-140674124 "Essential proteins, Predicted intracellular proteins" "rRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 76.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043470, HPA048143, HPA075133" Uncertain Enhanced Nucleoplasm,Nucleoli NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 49: Non-specific - Transcription" "Cluster 44: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 20: Non-specific - Transcription regulation" 9 Nucleoplasm Nucleoli "HPA043470: , HPA048143: , HPA075133: " "unprognostic (3.99e-2)" "unprognostic (1.63e-3)" "unprognostic (4.18e-1)" "unprognostic (2.28e-3)" "unprognostic (1.04e-1)" "unprognostic (1.53e-1)" "unprognostic (9.09e-3)" "unprognostic (1.54e-1)" "unprognostic (2.70e-2)" "unprognostic (1.11e-3)" "unprognostic (1.01e-2)" "unprognostic (1.96e-1)" "unprognostic (2.97e-2)" "potential prognostic unfavorable (1.25e-5)" "unprognostic (5.96e-2)" "unprognostic (1.22e-2)" "unprognostic (2.15e-2)" "unprognostic (6.03e-3)" "unprognostic (1.50e-1)" "unprognostic (1.27e-1)" "unprognostic (2.66e-1)" "unprognostic (3.90e-2)" "unprognostic (2.78e-1)" "unprognostic (6.44e-2)" "unprognostic (2.80e-1)" "unprognostic (7.06e-3)" "unprognostic (6.39e-2)" "unprognostic (1.65e-1)" "unprognostic (1.45e-1)" "unprognostic (3.41e-2)" "unprognostic (1.86e-1)" WDR59 FLJ12270 ENSG00000103091 "WD repeat domain 59" Q6PJI9 16 74871362-75000173 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041084, HPA048218" Approved Approved Vesicles,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 11: White matter - Signal transduction" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Transcription" 49 "Vesicles, Cytosol" "HPA041084: , HPA048218: " "unprognostic (2.54e-1)" "unprognostic (2.73e-2)" "unprognostic (5.02e-2)" "unprognostic (2.92e-2)" "unprognostic (5.91e-2)" "unprognostic (7.72e-2)" "unprognostic (1.07e-1)" "unprognostic (1.82e-3)" "unprognostic (2.91e-1)" "unprognostic (2.22e-1)" "unprognostic (1.60e-3)" "unprognostic (2.69e-3)" "unprognostic (2.27e-3)" "unprognostic (1.30e-1)" "unprognostic (2.66e-1)" "unprognostic (2.09e-1)" "unprognostic (4.64e-2)" "unprognostic (5.35e-2)" "unprognostic (2.22e-2)" "unprognostic (4.40e-2)" "unprognostic (3.22e-1)" "unprognostic (3.03e-1)" "unprognostic (2.23e-3)" "unprognostic (1.68e-3)" "potential prognostic favorable (6.61e-4)" "unprognostic (1.53e-1)" "unprognostic (1.78e-1)" "unprognostic (6.50e-2)" "unprognostic (8.13e-2)" "unprognostic (3.83e-2)" "unprognostic (7.60e-2)" WDR5B FLJ11287 ENSG00000196981 "WD repeat domain 5B" Q86VZ2 3 122411846-122416062 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 21.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042994, HPA076612" Approved Supported Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 22: Epididymis - Mixed function" "Cluster 46: Brainstem - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" 16 Nucleoplasm "HPA042994: , HPA076612: " "unprognostic (1.98e-2)" "unprognostic (1.88e-2)" "unprognostic (5.02e-1)" "unprognostic (2.36e-2)" "unprognostic (8.30e-3)" "unprognostic (1.43e-1)" "unprognostic (7.82e-2)" "unprognostic (4.19e-2)" "unprognostic (5.60e-2)" "unprognostic (4.78e-2)" "unprognostic (9.89e-2)" "unprognostic (2.97e-1)" "unprognostic (4.35e-3)" "unprognostic (5.04e-3)" "unprognostic (7.96e-2)" "unprognostic (1.07e-2)" "unprognostic (2.32e-3)" "unprognostic (1.41e-1)" "unprognostic (6.80e-2)" "unprognostic (3.68e-2)" "unprognostic (5.58e-2)" "unprognostic (3.89e-2)" "unprognostic (7.58e-2)" "unprognostic (1.94e-1)" "unprognostic (2.49e-3)" "unprognostic (5.28e-1)" "unprognostic (2.35e-2)" "unprognostic (1.16e-1)" "unprognostic (1.73e-1)" "unprognostic (1.14e-1)" "unprognostic (4.92e-2)" WDR6 Trm734 ENSG00000178252 "WD repeat domain 6" Q9NNW5 3 49007062-49015953 "Predicted intracellular proteins" "Cell cycle, tRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042622 Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 18: Non-specific - Translation" "Cluster 75: Ovary - Mixed function" "Cluster 46: Brainstem - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 46 Cytosol "Plasma membrane" "HPA042622: " "unprognostic (1.56e-2)" "unprognostic (2.39e-2)" "unprognostic (1.50e-1)" "unprognostic (1.06e-1)" "unprognostic (1.08e-1)" "unprognostic (5.05e-2)" "unprognostic (1.54e-1)" "unprognostic (1.21e-3)" "unprognostic (1.60e-1)" "potential prognostic unfavorable (3.47e-4)" "unprognostic (1.92e-1)" "unprognostic (1.16e-2)" "potential prognostic favorable (5.09e-5)" "potential prognostic unfavorable (9.70e-5)" "unprognostic (5.48e-2)" "unprognostic (1.04e-2)" "unprognostic (2.89e-2)" "unprognostic (1.11e-1)" "unprognostic (1.79e-1)" "unprognostic (1.11e-1)" "unprognostic (1.34e-1)" "unprognostic (4.22e-3)" "unprognostic (4.26e-2)" "unprognostic (4.61e-2)" "unprognostic (1.18e-1)" "unprognostic (1.44e-2)" "unprognostic (3.57e-2)" "unprognostic (1.90e-2)" "unprognostic (1.70e-1)" "unprognostic (1.56e-1)" "unprognostic (1.06e-3)" WDR62 "C19orf14, DKFZP434J046, FLJ33298, MCPH2" ENSG00000075702 "WD repeat domain 62" O43379 19 36054649-36105108 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Neurogenesis "Disease variant, Intellectual disability, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 103.4;testis: 66.9;tongue: 58.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 124.2;Differentiating spermatogonia: 40.1;Early primary spermatocytes: 107.3;Early spermatids: 35.8;Late primary spermatocytes: 76.9;Late spermatids: 64.9;Monocyte progenitors: 35.1;Rod photoreceptor cells: 89.6" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 24.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 2.7" "Lineage enriched" "Detected in single" 4 "monocytes: 2.7" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Cardiomyocytes, Lung - Mitotic cells (Lung), Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA043255, HPA043639" Enhanced Approved "Centriolar satellite,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 48: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 27: Non-specific - Cell proliferation" 49 Cytosol "Centriolar satellite" "HPA043255: , HPA043639: " "unprognostic (1.11e-1)" "unprognostic (5.22e-1)" "unprognostic (1.36e-1)" "unprognostic (5.83e-3)" "unprognostic (3.84e-2)" "unprognostic (1.59e-1)" "unprognostic (3.06e-1)" "unprognostic (1.99e-2)" "unprognostic (9.87e-3)" "potential prognostic unfavorable (2.99e-5)" "unprognostic (3.27e-3)" "validated prognostic unfavorable (1.43e-6)" "validated prognostic unfavorable (1.80e-4)" "unprognostic (4.06e-3)" "unprognostic (4.21e-2)" "potential prognostic favorable (7.94e-4)" "unprognostic (3.58e-2)" "unprognostic (4.24e-2)" "unprognostic (2.83e-2)" "unprognostic (4.79e-2)" "unprognostic (3.00e-2)" "unprognostic (1.05e-1)" "unprognostic (1.54e-2)" "unprognostic (1.60e-1)" "unprognostic (2.00e-1)" "unprognostic (4.59e-3)" "unprognostic (1.67e-1)" "unprognostic (1.40e-1)" WDR64 FLJ32978 ENSG00000162843 "WD repeat domain 64" B1ANS9 1 241652278-241802777 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in many" 10 "Early spermatids: 349.0;Late spermatids: 240.6" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Minor Salivary Gland - Minor salivary gland ductal cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA046186 Uncertain NA NA "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" "HPA046186: " WDR7 "KIAA0541, TRAG" ENSG00000091157 "WD repeat domain 7" Q9Y4E6 18 56651343-57029811 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042074, HPA051057" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 13: Non-specific - Mixed function" "Cluster 7: Non-specific - Transcription" 14 Nucleoplasm Cytosol "HPA042074: , HPA051057: " "unprognostic (5.81e-2)" "unprognostic (1.89e-1)" "unprognostic (2.84e-1)" "unprognostic (6.34e-2)" "unprognostic (4.91e-2)" "unprognostic (3.70e-2)" "unprognostic (1.06e-1)" "unprognostic (7.23e-2)" "unprognostic (7.77e-2)" "unprognostic (2.43e-2)" "potential prognostic favorable (1.92e-7)" "unprognostic (2.98e-3)" "unprognostic (3.01e-2)" "unprognostic (1.97e-1)" "unprognostic (3.62e-1)" "unprognostic (3.76e-1)" "unprognostic (1.30e-1)" "unprognostic (1.99e-1)" "unprognostic (3.34e-1)" "unprognostic (1.40e-1)" "unprognostic (2.24e-2)" "unprognostic (1.40e-2)" "unprognostic (8.80e-2)" "unprognostic (8.01e-2)" "unprognostic (2.03e-1)" "unprognostic (1.28e-1)" "unprognostic (7.05e-2)" "unprognostic (8.10e-3)" "unprognostic (5.40e-2)" "unprognostic (3.54e-2)" "unprognostic (6.66e-2)" WDR70 FLJ10233 ENSG00000082068 "WD repeat domain 70" Q9NW82 5 37379285-37753435 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043064, HPA048149" Uncertain Approved Mitochondria,Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 29: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 3 "Mitochondria, Cytosol" "HPA043064: , HPA048149: " "unprognostic (2.90e-1)" "unprognostic (8.86e-2)" "unprognostic (7.05e-2)" "unprognostic (2.39e-1)" "unprognostic (2.03e-1)" "unprognostic (6.89e-3)" "unprognostic (3.01e-2)" "unprognostic (2.72e-2)" "unprognostic (1.90e-1)" "unprognostic (2.47e-3)" "potential prognostic favorable (4.10e-6)" "unprognostic (7.21e-2)" "unprognostic (7.41e-2)" "unprognostic (3.49e-3)" "unprognostic (1.36e-2)" "unprognostic (2.50e-1)" "unprognostic (2.37e-2)" "unprognostic (3.30e-1)" "unprognostic (3.01e-2)" "unprognostic (1.42e-2)" "unprognostic (6.14e-2)" "unprognostic (2.46e-3)" "unprognostic (5.66e-3)" "unprognostic (4.97e-2)" "potential prognostic favorable (6.69e-4)" "unprognostic (8.58e-2)" "unprognostic (1.30e-2)" "unprognostic (1.78e-2)" "unprognostic (2.67e-1)" "unprognostic (1.25e-2)" "unprognostic (3.55e-1)" WDR72 FLJ38736 ENSG00000166415 "WD repeat domain 72" Q3MJ13 15 53513741-53762878 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Biomineralization "Amelogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 98.7;liver: 30.9;thyroid gland: 54.3" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 560.4;Epididymal clear cells: 259.2;Loop of henle epithelial cells: 258.6;Proximal tubule cells: 1125.4;Renal collecting duct intercalated cells: 1192.4;Renal collecting duct principal cells: 329.5;Renal connecting tubule cells: 510.9;Salivary basal cells: 197.0;Salivary duct cells: 581.1;Salivary ionocytes: 377.8" "Cell type enhanced" "Detected in some" "vascular associated smooth muscle cell: 5.2" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 34.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 14.0" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Minor Salivary Gland - Minor salivary gland ductal cells, Prostate - Urothelial cells, Skin - Eccrine sweat gland cells, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA048212, HPA057410, HPA059819" Uncertain Approved Vesicles NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 56: Non-specific - Sensory perception" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 1 Vesicles "HPA048212: , HPA057410: , HPA059819: " "unprognostic (1.23e-1)" "unprognostic (2.09e-2)" "unprognostic (6.88e-2)" "unprognostic (2.13e-2)" "unprognostic (1.20e-2)" "unprognostic (1.92e-1)" "unprognostic (2.30e-1)" "unprognostic (1.28e-2)" "validated prognostic favorable (4.77e-14)" "validated prognostic favorable (1.02e-4)" "unprognostic (6.30e-2)" "unprognostic (6.49e-2)" "unprognostic (2.13e-1)" "unprognostic (1.92e-1)" "unprognostic (1.72e-1)" "unprognostic (1.21e-2)" "unprognostic (2.12e-1)" "unprognostic (1.76e-1)" "unprognostic (1.09e-1)" "unprognostic (3.20e-2)" "unprognostic (1.00e-1)" "unprognostic (5.17e-2)" "unprognostic (7.31e-3)" "unprognostic (3.92e-2)" "unprognostic (2.58e-2)" "unprognostic (2.59e-3)" "unprognostic (1.02e-1)" WDR73 "FLJ14888, HSPC264" ENSG00000177082 "WD repeat domain 73" Q6P4I2 15 84639285-84654343 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 114.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039357 Uncertain NA NA "Cluster 24: Non-specific - Transcription" "Cluster 42: Retina - Visual perception" "Cluster 25: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 2 "HPA039357: " "unprognostic (2.61e-1)" "unprognostic (5.46e-3)" "unprognostic (2.55e-1)" "unprognostic (8.65e-3)" "unprognostic (1.36e-1)" "unprognostic (7.80e-2)" "unprognostic (1.74e-1)" "unprognostic (2.23e-2)" "unprognostic (1.25e-1)" "unprognostic (5.60e-2)" "unprognostic (2.51e-1)" "unprognostic (1.21e-2)" "unprognostic (4.12e-2)" "unprognostic (3.59e-3)" "unprognostic (9.72e-2)" "unprognostic (3.49e-2)" "unprognostic (1.26e-1)" "unprognostic (5.25e-1)" "unprognostic (1.84e-2)" "unprognostic (1.14e-1)" "unprognostic (9.83e-2)" "unprognostic (1.29e-1)" "unprognostic (9.20e-3)" "unprognostic (4.75e-2)" "unprognostic (5.84e-3)" "unprognostic (9.48e-2)" "unprognostic (2.63e-1)" "unprognostic (2.52e-1)" "unprognostic (2.56e-1)" "potential prognostic unfavorable (9.14e-4)" "unprognostic (1.01e-2)" WDR74 "FLJ10439, Nsa1" ENSG00000133316 "WD repeat domain 74" Q6RFH5 11 62832342-62841809 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 119.2" "Cell type enhanced" "Detected in many" "Gastric chief cells: 161.6;Innate lymphoid cells: 131.7;Mucous neck cells: 147.0;pDCs: 135.9;Plasma cells: 199.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Uterine Corpus Endometrial Carcinoma (TCGA): 886.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037795, HPA038419" Uncertain Supported Nucleoplasm,Nucleoli NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 20: Non-specific - Transcription regulation" 6 "Nucleoplasm, Nucleoli" "HPA037795: , HPA038419: " "potential prognostic unfavorable (2.71e-4)" "unprognostic (1.49e-1)" "unprognostic (1.81e-1)" "unprognostic (2.22e-1)" "unprognostic (1.44e-1)" "unprognostic (1.12e-1)" "unprognostic (3.56e-1)" "potential prognostic favorable (7.50e-4)" "potential prognostic unfavorable (3.91e-4)" "unprognostic (2.01e-1)" "unprognostic (7.56e-2)" "unprognostic (3.07e-3)" "unprognostic (8.32e-2)" "potential prognostic unfavorable (3.46e-4)" "unprognostic (7.57e-3)" "unprognostic (6.88e-3)" "potential prognostic unfavorable (6.55e-4)" "unprognostic (1.60e-1)" "unprognostic (1.35e-1)" "unprognostic (4.13e-2)" "unprognostic (4.70e-1)" "potential prognostic unfavorable (7.28e-4)" "unprognostic (1.57e-2)" "unprognostic (1.28e-1)" "unprognostic (2.57e-2)" "potential prognostic favorable (6.72e-4)" "unprognostic (6.05e-3)" "unprognostic (1.97e-1)" "unprognostic (1.71e-1)" "unprognostic (9.51e-2)" "unprognostic (4.43e-2)" WDR75 "FLJ12519, NET16, UTP17" ENSG00000115368 "WD repeat domain 75" Q8IWA0 2 189441446-189475552 "Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Kupffer cells: 130.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 39: Testis - Nuclear processes" "Cluster 34: Non-specific - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 17: Non-specific - RNA processing" 20 "unprognostic (1.03e-1)" "unprognostic (7.30e-2)" "unprognostic (1.06e-1)" "unprognostic (2.75e-2)" "unprognostic (6.36e-2)" "unprognostic (3.28e-2)" "unprognostic (4.51e-2)" "unprognostic (5.46e-3)" "unprognostic (1.46e-2)" "unprognostic (4.17e-2)" "unprognostic (5.88e-2)" "unprognostic (1.08e-1)" "unprognostic (5.12e-3)" "potential prognostic unfavorable (1.39e-7)" "unprognostic (4.79e-3)" "unprognostic (1.11e-2)" "unprognostic (2.58e-3)" "unprognostic (1.17e-1)" "unprognostic (1.37e-1)" "unprognostic (2.43e-1)" "unprognostic (1.38e-1)" "unprognostic (1.77e-3)" "unprognostic (6.05e-2)" "unprognostic (3.49e-2)" "unprognostic (1.78e-1)" "unprognostic (1.47e-1)" "unprognostic (2.39e-3)" "unprognostic (3.05e-1)" "unprognostic (1.19e-1)" "unprognostic (7.60e-2)" "unprognostic (5.28e-2)" WDR76 FLJ12973 ENSG00000092470 "WD repeat domain 76" Q9H967 15 43826980-43868412 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 18.0;lymphoid tissue: 20.0" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 55.0;Early primary spermatocytes: 56.1;Erythrocyte progenitors: 92.5;Megakaryocyte progenitors: 62.4;Monocyte progenitors: 70.1;Neutrophil progenitors: 65.3;Oocytes: 82.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Skeletal muscle - Endothelial cells, Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039804, HPA040626" Uncertain Approved "Nucleoli fibrillar center,Nuclear bodies" NA Yes "Cluster 43: Non-specific - Transcription & Translation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 2: Neurons - Nucleosome" "Cluster 58: Non-specific - Nuclear processes" "Cluster 27: Non-specific - Cell proliferation" 70 "Nuclear bodies" "Nucleoli fibrillar center" "HPA039804: , HPA040626: " "unprognostic (4.60e-2)" "unprognostic (1.18e-1)" "unprognostic (5.04e-2)" "unprognostic (1.26e-1)" "unprognostic (9.24e-2)" "unprognostic (2.72e-1)" "unprognostic (1.21e-1)" "potential prognostic favorable (6.16e-4)" "unprognostic (9.61e-3)" "potential prognostic unfavorable (9.57e-4)" "potential prognostic favorable (3.88e-5)" "unprognostic (1.26e-1)" "unprognostic (4.88e-2)" "validated prognostic unfavorable (1.06e-4)" "validated prognostic unfavorable (1.03e-4)" "potential prognostic unfavorable (2.14e-4)" "unprognostic (1.09e-3)" "unprognostic (5.71e-2)" "unprognostic (2.29e-1)" "unprognostic (3.34e-1)" "unprognostic (1.44e-1)" "unprognostic (2.15e-3)" "unprognostic (1.37e-2)" "unprognostic (2.14e-2)" "unprognostic (2.24e-2)" "unprognostic (2.70e-1)" "unprognostic (1.08e-1)" "unprognostic (1.03e-1)" "unprognostic (2.78e-1)" "unprognostic (1.16e-1)" "unprognostic (9.37e-2)" WDR77 "MEP50, p44" ENSG00000116455 "WD repeat domain 77" Q9BQA1 1 111439890-111449256 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "fallopian tube: 98.8" "Cell type enhanced" "Detected in many" "Fallopian secretory cells: 18.3;Fallopian tube ciliated cells: 17.3;Tuft cells: 23.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026437, HPA026448, HPA027271" Enhanced Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 54000 "Cluster 13: Non-specific - Mitochondria" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 37: Non-specific - mRNA processing" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 87 "Nucleoplasm, Cytosol" "Golgi apparatus" "HPA026437: , HPA026448: , HPA027271: " "unprognostic (3.12e-1)" "unprognostic (1.10e-2)" "unprognostic (1.80e-1)" "unprognostic (5.60e-2)" "unprognostic (1.01e-1)" "unprognostic (4.04e-3)" "unprognostic (3.62e-1)" "potential prognostic favorable (7.56e-4)" "unprognostic (5.18e-2)" "unprognostic (1.01e-1)" "unprognostic (7.13e-2)" "unprognostic (1.74e-1)" "unprognostic (6.45e-2)" "validated prognostic unfavorable (1.52e-12)" "validated prognostic unfavorable (2.35e-7)" "unprognostic (1.42e-2)" "unprognostic (3.23e-2)" "unprognostic (9.16e-2)" "unprognostic (3.53e-2)" "unprognostic (1.35e-2)" "unprognostic (1.43e-1)" "unprognostic (7.60e-2)" "unprognostic (4.24e-2)" "unprognostic (7.17e-3)" "unprognostic (1.17e-2)" "unprognostic (1.72e-1)" "unprognostic (3.10e-3)" "unprognostic (2.81e-1)" "unprognostic (1.43e-1)" "unprognostic (6.06e-2)" "unprognostic (2.89e-1)" WDR81 "CAMRQ2, FLJ33817, PPP1R166, SORF-2" ENSG00000167716 "WD repeat domain 81" Q562E7 17 1716523-1738599 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 28.6;Hepatocytes: 22.1;Kupffer cells: 20.5;Microglia: 30.8;Proximal tubule cells: 25.3" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 38.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Heart muscle - Macrophages, Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023044, HPA063703" Uncertain Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 27: Non-specific - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 102: Non-specific - Mixed function" 3 Nucleoplasm "Vesicles, Cytosol" "HPA023044: , HPA063703: " "unprognostic (2.57e-1)" "unprognostic (2.23e-1)" "unprognostic (1.37e-2)" "unprognostic (9.28e-3)" "unprognostic (5.53e-2)" "unprognostic (1.37e-1)" "unprognostic (8.74e-2)" "unprognostic (2.84e-1)" "unprognostic (5.24e-3)" "unprognostic (1.17e-2)" "unprognostic (4.20e-1)" "unprognostic (4.35e-2)" "unprognostic (2.12e-3)" "unprognostic (9.73e-2)" "unprognostic (3.00e-2)" "unprognostic (1.10e-1)" "unprognostic (2.66e-1)" "unprognostic (1.10e-1)" "unprognostic (1.35e-1)" "unprognostic (2.64e-2)" "unprognostic (3.76e-1)" "unprognostic (2.28e-2)" "unprognostic (1.43e-1)" "unprognostic (2.17e-1)" "unprognostic (4.38e-1)" "unprognostic (3.89e-2)" "unprognostic (9.80e-2)" "unprognostic (2.11e-1)" "unprognostic (2.67e-2)" "unprognostic (5.59e-2)" "potential prognostic favorable (7.54e-4)" WDR82 "MST107, MSTP107, PRO2730, PRO34047, SWD2, TMEM113, WDR82A" ENSG00000164091 "WD repeat domain 82" Q6UXN9 3 52254434-52288020 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Transcription termination" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 309.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040427 Approved "Nucleoli rim" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 17: Non-specific - RNA processing" 48 "Nucleoli rim" "HPA040427: " "unprognostic (5.97e-3)" "unprognostic (2.03e-1)" "unprognostic (6.77e-2)" "unprognostic (4.47e-2)" "unprognostic (1.26e-1)" "unprognostic (2.06e-2)" "unprognostic (1.29e-1)" "unprognostic (3.02e-1)" "unprognostic (2.03e-3)" "unprognostic (3.37e-2)" "potential prognostic favorable (1.49e-4)" "unprognostic (3.30e-2)" "unprognostic (1.42e-1)" "unprognostic (1.57e-2)" "unprognostic (2.44e-3)" "unprognostic (2.45e-1)" "unprognostic (2.64e-3)" "unprognostic (5.72e-2)" "unprognostic (1.90e-1)" "unprognostic (3.25e-1)" "unprognostic (4.29e-2)" "unprognostic (5.00e-1)" "unprognostic (1.72e-1)" "unprognostic (3.48e-3)" "unprognostic (1.53e-1)" "unprognostic (8.37e-2)" "unprognostic (5.89e-3)" "unprognostic (1.20e-1)" "unprognostic (4.18e-1)" "unprognostic (5.12e-2)" "unprognostic (4.78e-2)" WDR83 MORG1 ENSG00000123154 "WD repeat domain 83" Q9BRX9 19 12666802-12675832 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 85.7;Epicardial cells: 88.7;Late spermatids: 113.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042629, HPA042838" Uncertain Approved "Nucleoplasm,Vesicles,Centriolar satellite,Basal body,Cytosol" NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 64: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 90 "Nucleoplasm, Vesicles" "Centriolar satellite, Basal body, Cytosol" "HPA042629: , HPA042838: " "unprognostic (6.40e-2)" "unprognostic (1.36e-1)" "unprognostic (5.33e-2)" "unprognostic (3.09e-2)" "unprognostic (1.46e-2)" "unprognostic (1.52e-1)" "unprognostic (1.33e-1)" "unprognostic (7.97e-3)" "unprognostic (2.29e-1)" "unprognostic (3.33e-3)" "potential prognostic favorable (2.20e-7)" "unprognostic (4.11e-3)" "unprognostic (3.13e-2)" "unprognostic (2.75e-1)" "unprognostic (1.26e-2)" "unprognostic (1.13e-2)" "unprognostic (2.65e-1)" "unprognostic (3.34e-1)" "unprognostic (8.54e-2)" "unprognostic (3.89e-2)" "unprognostic (3.11e-1)" "unprognostic (3.31e-2)" "unprognostic (7.75e-2)" "unprognostic (2.10e-2)" "unprognostic (1.89e-1)" "unprognostic (6.30e-2)" "unprognostic (5.84e-2)" "unprognostic (4.03e-2)" "unprognostic (3.37e-1)" "unprognostic (2.87e-1)" "unprognostic (5.82e-2)" WDR83OS "Asterix, C19orf56, PTD008" ENSG00000105583 "WD repeat domain 83 opposite strand" Q9Y284 19 12668073-12669415 "Predicted membrane proteins, Transporters" Chaperone "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 2.5;Bergmann glia: 3.5;Brain excitatory neurons: 5.6;Brain inhibitory neurons: 3.1;Ependymal cells: 3.9;Microglia: 7.7;Oligodendrocyte progenitor cells: 4.7;Oligodendrocytes: 14.8;Other brain neurons: 9.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065685 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 70: Non-specific - Protein processing" "Cluster 27: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 98: Neurons - Neurotransmission & signaling" 4 "Endoplasmic reticulum" "HPA065685: " "unprognostic (1.42e-1)" "unprognostic (4.46e-2)" "unprognostic (2.12e-3)" "unprognostic (1.98e-1)" "unprognostic (1.50e-1)" "unprognostic (1.30e-1)" "unprognostic (1.27e-1)" "unprognostic (2.23e-1)" "unprognostic (1.32e-1)" "unprognostic (2.14e-3)" "unprognostic (2.89e-1)" "unprognostic (2.02e-1)" "potential prognostic unfavorable (1.86e-4)" "unprognostic (1.25e-1)" "unprognostic (7.36e-2)" "potential prognostic favorable (3.71e-4)" "unprognostic (1.72e-1)" "potential prognostic favorable (1.79e-5)" "unprognostic (9.47e-2)" "unprognostic (2.24e-1)" "unprognostic (2.42e-1)" "unprognostic (1.55e-1)" "unprognostic (3.52e-2)" "unprognostic (5.05e-2)" "unprognostic (8.70e-3)" "unprognostic (1.29e-1)" "unprognostic (1.28e-1)" "unprognostic (2.66e-1)" "unprognostic (2.33e-1)" WDR86 ENSG00000187260 "WD repeat domain 86" Q86TI4 7 151375909-151410727 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "thyroid gland: 27.6" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 32.7;Decidual stromal cells: 54.0;Endometrial stromal cells: 43.3;Ependymal cells: 70.9;Epididymal efferent duct ciliated cells: 42.8;Fallopian tube ciliated cells: 49.8;Fibro-adipogenic progenitors: 41.0;Fibroblasts: 35.9;Innate lymphoid cells: 39.5;Müller glia: 37.8;Pituicytes/FSCs: 57.3;Respiratory ciliated cells: 36.3" "Cell type enhanced" "Detected in many" "ependymal cell: 69.6;fibroblast: 181.8" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 35.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Neuroblastoma: 10.4;testis cancer: 3.5" "Colon - Enteric glia cells, Stomach - Chief cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA021086 Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 64: Non-specific - Transcription" "Cluster 23: Choroid plexus - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 108: Fibroblasts - ECM organization" Nucleoplasm "Plasma membrane, Cytosol" "HPA021086: " "unprognostic (2.04e-1)" "unprognostic (3.62e-2)" "unprognostic (1.23e-1)" "unprognostic (1.08e-2)" "unprognostic (9.53e-2)" "unprognostic (1.42e-3)" "unprognostic (1.10e-1)" "unprognostic (2.42e-1)" "unprognostic (5.50e-2)" "unprognostic (3.76e-3)" "unprognostic (2.34e-1)" "unprognostic (2.66e-2)" "unprognostic (6.41e-2)" "unprognostic (4.32e-2)" "unprognostic (7.81e-2)" "unprognostic (1.12e-1)" "unprognostic (3.03e-2)" "unprognostic (7.22e-2)" "unprognostic (2.04e-1)" "unprognostic (7.70e-2)" "unprognostic (3.57e-1)" WDR87 NYD-SP11 ENSG00000171804 "WD repeat domain 87" Q6ZQQ6 19 37884823-37906677 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 46 "testis: 15.9" "Group enriched" "Detected in some" 4 "Early primary spermatocytes: 44.2;Late primary spermatocytes: 147.1" "Low cell type specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 4: Non-specific - Transcription" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" WDR88 PQWD ENSG00000166359 "WD repeat domain 88" Q6ZMY6 19 33132090-33175799 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 8.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 31.6;Cone photoreceptor cells: 20.7;Early spermatids: 27.1;Late primary spermatocytes: 64.3;Late spermatids: 20.5" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041916, HPA050336" Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 47: Testis - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" "Nucleoplasm, Golgi apparatus" "HPA041916: , HPA050336: " "unprognostic (1.49e-1)" "unprognostic (7.02e-2)" "unprognostic (2.95e-2)" "unprognostic (2.20e-1)" "unprognostic (2.12e-2)" "unprognostic (9.40e-3)" WDR89 "C14orf150, MGC9907" ENSG00000140006 "WD repeat domain 89" Q96FK6 14 63597039-63641871 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000813 Uncertain Approved "Intermediate filaments,Cytosol" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 31: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 7: Non-specific - Transcription" 6 "Intermediate filaments, Cytosol" "HPA000813: " "unprognostic (1.49e-1)" "unprognostic (2.39e-1)" "unprognostic (1.31e-2)" "unprognostic (3.09e-3)" "unprognostic (4.58e-2)" "unprognostic (2.10e-1)" "unprognostic (2.38e-1)" "unprognostic (3.91e-2)" "unprognostic (2.16e-1)" "unprognostic (3.71e-3)" "potential prognostic favorable (1.38e-5)" "unprognostic (1.12e-2)" "unprognostic (2.22e-1)" "unprognostic (2.39e-3)" "unprognostic (1.70e-1)" "unprognostic (7.47e-2)" "unprognostic (2.21e-1)" "unprognostic (6.87e-2)" "unprognostic (2.60e-2)" "unprognostic (2.49e-1)" "unprognostic (1.34e-3)" "unprognostic (3.38e-2)" "unprognostic (4.45e-2)" "unprognostic (1.33e-1)" "unprognostic (6.57e-2)" "unprognostic (4.39e-2)" "unprognostic (3.54e-2)" "unprognostic (1.57e-1)" "unprognostic (1.70e-1)" "unprognostic (2.85e-1)" "unprognostic (2.53e-1)" WDR90 "C16orf15, C16orf16, C16orf17, C16orf18, C16orf19, FLJ36483, KIAA1924, POC16" ENSG00000161996 "WD repeat domain 90" Q96KV7 16 649311-667833 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 59.4" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 32.7;Early primary spermatocytes: 36.5;Endometrial ciliated cells: 42.2;Ependymal cells: 40.5;Fallopian tube ciliated cells: 38.0;Respiratory ciliated cells: 62.9" "Cell type enhanced" "Detected in all" "ependymal cell: 43.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.2" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA049362 Approved Supported "Plasma membrane,Centrosome,Basal body" NA NA "Cluster 21: Testis - Mixed function" "Cluster 17: Choroid plexus - Cilium" "Cluster 54: Non-specific - Transcription" "Cluster 107: Ciliated cells - Cilia assembly & function" 1 "Centrosome, Basal body" "Plasma membrane" "HPA049362: " "unprognostic (1.70e-2)" "unprognostic (8.91e-3)" "unprognostic (2.35e-1)" "potential prognostic favorable (9.62e-4)" "unprognostic (2.16e-1)" "unprognostic (1.30e-1)" "unprognostic (4.23e-2)" "unprognostic (8.92e-2)" "potential prognostic favorable (4.80e-4)" "unprognostic (5.63e-2)" "potential prognostic unfavorable (2.50e-6)" "unprognostic (1.26e-2)" "unprognostic (4.47e-3)" "unprognostic (7.92e-2)" "unprognostic (1.69e-1)" "unprognostic (2.63e-1)" "unprognostic (2.57e-1)" "unprognostic (4.69e-2)" "unprognostic (5.98e-2)" "unprognostic (2.05e-1)" "unprognostic (2.79e-2)" "unprognostic (9.53e-2)" "unprognostic (1.17e-2)" "unprognostic (1.55e-2)" "potential prognostic favorable (9.10e-4)" "unprognostic (7.34e-2)" "unprognostic (1.57e-1)" "unprognostic (1.11e-1)" "unprognostic (2.67e-1)" "unprognostic (1.70e-2)" "unprognostic (3.15e-2)" WDR91 "HSPC049, SORF-1" ENSG00000105875 "WD repeat domain 91" A4D1P6 7 135183839-135211555 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 17.5" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 75.7;Distal convoluted tubule cells: 80.2;Early spermatids: 61.5;Hofbauer cells: 84.7;Late spermatids: 95.2;Loop of henle epithelial cells: 59.8;Renal connecting tubule cells: 62.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024260 Uncertain NA NA "Cluster 18: Non-specific - Translation" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 3 "HPA024260: " "unprognostic (1.19e-1)" "unprognostic (4.56e-2)" "unprognostic (1.04e-1)" "unprognostic (7.89e-2)" "unprognostic (4.17e-3)" "unprognostic (1.06e-1)" "unprognostic (6.59e-2)" "unprognostic (2.00e-1)" "unprognostic (3.61e-2)" "unprognostic (4.33e-2)" "unprognostic (1.93e-2)" "unprognostic (2.63e-1)" "unprognostic (5.79e-3)" "potential prognostic unfavorable (1.57e-4)" "unprognostic (8.97e-3)" "potential prognostic favorable (9.73e-4)" "unprognostic (2.50e-1)" "unprognostic (2.04e-1)" "unprognostic (3.43e-3)" "unprognostic (3.32e-3)" "unprognostic (2.43e-1)" "unprognostic (3.06e-3)" "unprognostic (1.45e-1)" "unprognostic (1.26e-2)" "unprognostic (1.42e-1)" "unprognostic (3.82e-2)" "unprognostic (2.03e-1)" "unprognostic (1.50e-1)" "unprognostic (1.10e-1)" "unprognostic (2.94e-1)" "unprognostic (6.34e-2)" WDR93 "C1d-87, CFAP297, FAP297" ENSG00000140527 "WD repeat domain 93" Q6P2C0 15 89690811-89743638 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 6.6;fallopian tube: 8.4;testis: 10.8" "Cell type enhanced" "Detected in many" "Adipocytes: 101.2;Choroid plexus epithelial cells: 51.1;Early spermatids: 103.8;Endometrial ciliated cells: 61.3;Ependymal cells: 183.3;Epididymal efferent duct ciliated cells: 63.0;Fallopian tube ciliated cells: 96.2;Late primary spermatocytes: 137.0;Late spermatids: 70.3;Respiratory ciliated cells: 141.7" "Group enriched" "Detected in many" 11 "choroid plexus epithelial cell: 54.0;ependymal cell: 191.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA046196, HPA048112" Uncertain Approved "Actin filaments" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 27: Breast cancer - Unknown function" "Cluster 34: Ciliated cells - Cilia assembly & function" "Actin filaments" "HPA046196: , HPA048112: " "unprognostic (1.25e-1)" "unprognostic (4.61e-1)" "unprognostic (2.20e-2)" "unprognostic (1.15e-3)" "unprognostic (3.49e-2)" "unprognostic (1.70e-1)" "unprognostic (9.48e-2)" "unprognostic (6.54e-2)" "unprognostic (6.10e-2)" "unprognostic (2.01e-1)" "unprognostic (5.47e-3)" "unprognostic (4.85e-2)" "unprognostic (1.45e-1)" WDR97 KIAA1875 ENSG00000179698 "WD repeat domain 97" A6NE52 8 144107726-144118328 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 5 "testis: 1.4" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 10.5;Brain inhibitory neurons: 9.3;Choroid plexus epithelial cells: 11.0;Cone photoreceptor cells: 6.2;Late primary spermatocytes: 7.1;Paneth cells: 11.6" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" HPA059409 Uncertain NA NA "Cluster 67: Testis - Mixed function" "Cluster 35: Neurons - Synaptic function & neurogenesis" "HPA059409: " "unprognostic (3.87e-3)" WDSUB1 "FLJ36175, UBOX6, WDSAM1" ENSG00000196151 "WD repeat, sterile alpha motif and U-box domain containing 1" Q8N9V3 2 159235798-159286703 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 211.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036840, HPA058172" Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 72: Kidney - Transmembrane transport" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" Nucleoli "Nucleoplasm, Cytosol" "HPA036840: , HPA058172: " "unprognostic (2.15e-3)" "unprognostic (1.55e-3)" "unprognostic (2.12e-1)" "unprognostic (6.12e-2)" "unprognostic (2.34e-1)" "unprognostic (3.21e-2)" "potential prognostic unfavorable (4.71e-4)" "unprognostic (6.30e-2)" "unprognostic (1.64e-1)" "unprognostic (2.79e-3)" "potential prognostic favorable (2.59e-7)" "unprognostic (2.90e-2)" "unprognostic (3.80e-1)" "unprognostic (2.39e-3)" "potential prognostic unfavorable (9.53e-4)" "unprognostic (1.41e-1)" "unprognostic (9.66e-2)" "unprognostic (3.46e-1)" "unprognostic (2.65e-3)" "unprognostic (3.21e-1)" "unprognostic (1.79e-1)" "unprognostic (3.00e-2)" "unprognostic (1.32e-2)" "unprognostic (7.12e-2)" "unprognostic (2.71e-1)" "unprognostic (2.99e-2)" "unprognostic (3.48e-2)" "unprognostic (6.92e-2)" "unprognostic (3.16e-1)" "unprognostic (1.81e-2)" "unprognostic (4.02e-2)" WDTC1 "ADP, DCAF9, KIAA1037" ENSG00000142784 "WD and tetratricopeptide repeats 1" Q8N5D0 1 27234632-27308636 "Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 176.0;Neutrophils: 166.9;Rod photoreceptor cells: 240.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028177, HPA028180, HPA028182" Uncertain Supported "Golgi apparatus,Vesicles" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 16 Vesicles "Golgi apparatus" "HPA028177: , HPA028180: , HPA028182: " "potential prognostic favorable (7.18e-4)" "unprognostic (7.40e-2)" "unprognostic (7.27e-2)" "unprognostic (3.06e-2)" "unprognostic (5.51e-2)" "unprognostic (3.03e-2)" "unprognostic (1.23e-1)" "unprognostic (2.70e-2)" "unprognostic (2.30e-2)" "unprognostic (4.17e-2)" "potential prognostic favorable (5.28e-6)" "unprognostic (3.44e-3)" "potential prognostic favorable (2.48e-5)" "unprognostic (2.42e-2)" "unprognostic (3.79e-2)" "unprognostic (2.39e-2)" "unprognostic (2.95e-1)" "unprognostic (5.40e-2)" "unprognostic (2.32e-1)" "unprognostic (1.57e-2)" "unprognostic (2.92e-2)" "unprognostic (9.68e-3)" "potential prognostic favorable (4.33e-4)" "unprognostic (2.24e-1)" "unprognostic (6.32e-3)" "unprognostic (2.54e-1)" "unprognostic (3.33e-1)" "unprognostic (1.74e-1)" "unprognostic (2.97e-2)" "unprognostic (1.65e-1)" "unprognostic (1.24e-1)" WEE1 WEE1A ENSG00000166483 "WEE1 G2 checkpoint kinase" P30291 11 9573670-9593457 "Cancer-related genes, Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 257.6;Breast secretory cells: 258.2;Endometrial glandular cells: 345.2;Endometrial luminal cells: 264.0;Extravillous trophoblasts: 278.8;Ocular epithelial cells: 344.4;Urothelial cells: 299.7" "Cell type enhanced" "Detected in many" "ependymal cell: 18.5;fibroblast: 18.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB004619, HPA068845" Approved Supported Nucleoli No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 58: Skin - Keratinization" "Cluster 44: Non-specific - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 100: Stratified epithelial cells - Barrier functions" 41 Nucleoli "CAB004619: , HPA068845: " "unprognostic (8.29e-2)" "unprognostic (2.13e-1)" "unprognostic (1.53e-1)" "unprognostic (7.53e-3)" "unprognostic (5.89e-2)" "unprognostic (5.63e-3)" "unprognostic (1.27e-1)" "unprognostic (1.86e-1)" "unprognostic (1.78e-2)" "unprognostic (2.67e-1)" "unprognostic (1.74e-3)" "unprognostic (2.14e-1)" "unprognostic (5.80e-2)" "unprognostic (5.51e-3)" "unprognostic (1.16e-2)" "unprognostic (2.67e-2)" "unprognostic (3.69e-2)" "unprognostic (2.64e-1)" "unprognostic (2.47e-2)" "unprognostic (5.70e-3)" "unprognostic (1.42e-1)" "unprognostic (1.22e-2)" "potential prognostic unfavorable (7.67e-4)" "unprognostic (1.22e-1)" "unprognostic (4.23e-2)" "unprognostic (1.17e-2)" "unprognostic (6.28e-2)" "unprognostic (9.04e-2)" "unprognostic (5.12e-1)" "unprognostic (2.48e-1)" "unprognostic (1.79e-1)" WEE2 "FLJ16107, WEE1B" ENSG00000214102 "WEE2 oocyte meiosis inhibiting kinase" P0C1S8 7 141708353-141731271 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Meiosis "Kinase, Transferase, Tyrosine-protein kinase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 6 "Oocytes: 9.2" "Cell type enhanced" "Detected in some" "Bergmann glia: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA027418, HPA054280" Uncertain Supported Nucleoplasm NA NA "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 28: Astrocytes - Homeostasis & neuron support" Nucleoplasm "HPA027418: , HPA054280: " WFDC1 PS20 ENSG00000103175 "WAP four-disulfide core domain 1" Q9HC57 16 84294846-84329844 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 104.6;seminal vesicle: 108.3" "Cell type enhanced" "Detected in many" "Bergmann glia: 121.4;Hepatic stellate cells: 232.4;Late spermatids: 64.8;Megakaryocyte progenitors: 67.3;Megakaryocytes: 173.1;Oligodendrocyte progenitor cells: 73.1;Pericytes: 63.6;Peritubular myoid cells: 271.8;Platelets: 213.6;Retinal bipolar cells: 179.1;Retinal pigment epithelial cells: 68.2;Smooth muscle cells: 137.6;Vascular smooth muscle cells: 158.2" "Cell type enhanced" "Detected in many" "Bergmann glia: 110.6;oligodendrocyte precursor cell: 77.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "skin cancer: 74.4" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Heart muscle - Smooth muscle cells, Liver - Hepatic stellate cells, Lung - Smooth muscle cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Smooth muscle cells, Stomach - Fibroblasts, Testis - Peritubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031411 Uncertain "Secreted to extracellular matrix" "Enzyme inhibitor" NA NA 7700 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 15: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" "HPA031411: " "potential prognostic favorable (1.52e-4)" "unprognostic (5.87e-2)" "unprognostic (2.48e-2)" "unprognostic (3.13e-1)" "unprognostic (3.18e-2)" "unprognostic (1.26e-1)" "unprognostic (5.09e-2)" "potential prognostic favorable (6.97e-5)" "unprognostic (2.09e-3)" "unprognostic (1.46e-1)" "unprognostic (1.90e-3)" "unprognostic (1.46e-2)" "unprognostic (7.48e-2)" "unprognostic (1.13e-2)" "unprognostic (1.51e-2)" "unprognostic (1.42e-2)" "unprognostic (6.57e-2)" "unprognostic (3.78e-2)" "unprognostic (5.30e-2)" "unprognostic (6.22e-2)" "unprognostic (1.44e-1)" "unprognostic (1.78e-1)" "unprognostic (2.42e-2)" "unprognostic (3.49e-2)" "unprognostic (2.77e-1)" "unprognostic (7.52e-2)" "unprognostic (2.91e-2)" "unprognostic (6.55e-2)" "unprognostic (3.33e-1)" "unprognostic (7.50e-2)" "unprognostic (1.01e-1)" WFDC10A "C20orf146, dJ688G8.3, WAP10" ENSG00000180305 "WAP four-disulfide core domain 10A" Q9H1F0 20 45629739-45631196 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 439 "epididymis: 271.3" "Cell type enriched" "Detected in some" 83 "Epididymal principal cells: 492.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "thalamus: 1.9" "Not detected" "Not detected" "Secreted in male reproductive system" "Enzyme inhibitor" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" WFDC10B WAP12 ENSG00000182931 "WAP four-disulfide core domain 10B" Q8IUB3 20 45684651-45705019 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 25.6;retina: 10.6" "Group enriched" "Detected in many" 4 "Epididymal principal cells: 75.9;Rod photoreceptor cells: 203.2" "Cell type enriched" "Detected in many" 4 "ependymal cell: 29.3" "Cancer enhanced" "Detected in some" "Lung Adenocarcinoma (TCGA): 4.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Prostate - Smooth muscle cells, Skin - Eccrine sweat gland cells" HPA014046 Approved Vesicles "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 46: Brainstem - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 79: Photoreceptor cells - Phototransduction" 1 Vesicles "HPA014046: " "unprognostic (1.01e-1)" "unprognostic (1.53e-1)" "unprognostic (5.38e-3)" "potential prognostic unfavorable (9.24e-5)" "unprognostic (1.40e-1)" "unprognostic (3.06e-2)" "unprognostic (1.38e-1)" "unprognostic (9.38e-2)" WFDC11 WAP11 ENSG00000180083 "WAP four-disulfide core domain 11" Q8NEX6 20 45648563-45670270 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 19 "epididymis: 88.7" "Group enriched" "Detected in some" 25 "Early spermatids: 97.4;Epididymal principal cells: 164.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "basophil: 2.3" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.3" "Low cancer specificity" "Detected in some" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 9: Non-specific - Receptor signaling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" "unprognostic (2.31e-1)" "unprognostic (6.68e-2)" "unprognostic (1.56e-1)" WFDC12 "C20orf122, dJ211D12.4, WAP2" ENSG00000168703 "WAP four-disulfide core domain 12" Q8WWY7 20 45123425-45124465 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "skin 1: 39.6" "Group enriched" "Detected in some" 4 "Alveolar cells type 2: 8.0;Esophageal apical cells: 27.5" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Head and Neck Squamous Cell Carcinoma (TCGA): 29.8;Kidney Renal Papillary Cell Carcinoma (TCGA): 8.5;Skin Cutaneous Melanoma (TCGA): 32.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "head and neck cancer: 3.5" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Secreted in other tissues" "Enzyme inhibitor" NA NA 530000 "Cluster 37: Skin - Keratinization" "Cluster 9: Non-specific - Receptor signaling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 5 "unprognostic (3.89e-2)" "unprognostic (4.76e-2)" "unprognostic (2.16e-1)" "unprognostic (8.96e-2)" "unprognostic (3.63e-3)" "unprognostic (1.02e-1)" "unprognostic (7.96e-2)" "unprognostic (1.52e-2)" "unprognostic (1.49e-2)" "unprognostic (5.87e-2)" "unprognostic (5.68e-2)" "unprognostic (2.40e-1)" WFDC13 "C20orf138, dJ601O1.3, WAP13" ENSG00000168634 "WAP four-disulfide core domain 13" Q8IUB5 20 45702038-45708817 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 41 "epididymis: 84.5" "Cell type enriched" "Detected in some" 4 "Epididymal principal cells: 116.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" "Enzyme inhibitor" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" 1 WFDC2 "dJ461P17.6, EDDM4, HE4, WAP5" ENSG00000101443 "WAP four-disulfide core domain 2" Q14508 20 45469753-45481532 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Aspartic protease inhibitor, Protease inhibitor, Serine protease inhibitor, Thiol protease inhibitor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 4905.6;salivary gland: 1869.1" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 39115.1;Endometrial luminal cells: 8103.5;Endometrial secretory cells: 17349.9;Respiratory deuterosomal cells: 8385.3;Respiratory secretory cells: 10774.8;Salivary basal cells: 4993.7;Salivary duct cells: 38883.0;Submucosal glandular cells: 10204.5" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Ovary Serous Cystadenocarcinoma (TCGA): 4331.7;Uterine Corpus Endometrial Carcinoma (TCGA): 6074.1" "Region enhanced" "Detected in all" "choroid plexus: 36.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "ovarian cancer: 312.2;pancreatic cancer: 279.8" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Lung - Alveolar cells type 2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA042302 Enhanced "Secreted in other tissues" "Enzyme inhibitor" NA NA 4200000 "Cluster 38: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 16 "HPA042302: " "unprognostic (9.56e-3)" "unprognostic (9.11e-2)" "unprognostic (3.14e-2)" "unprognostic (2.20e-1)" "unprognostic (9.58e-2)" "unprognostic (1.36e-2)" "potential prognostic unfavorable (7.07e-5)" "unprognostic (3.84e-3)" "unprognostic (1.01e-2)" "unprognostic (1.68e-1)" "unprognostic (6.67e-2)" "unprognostic (2.78e-2)" "unprognostic (3.53e-2)" "unprognostic (2.39e-1)" "unprognostic (2.95e-2)" "unprognostic (3.62e-3)" "unprognostic (3.40e-2)" "unprognostic (3.25e-2)" "unprognostic (1.49e-1)" "unprognostic (1.38e-1)" "unprognostic (1.06e-1)" "unprognostic (9.56e-2)" "unprognostic (1.03e-1)" "unprognostic (4.80e-2)" "unprognostic (1.37e-1)" "potential prognostic unfavorable (6.05e-4)" "unprognostic (3.17e-3)" "unprognostic (6.93e-2)" "unprognostic (1.94e-1)" "unprognostic (2.78e-2)" "unprognostic (1.54e-1)" WFDC3 "dJ447F3.3, WAP14" ENSG00000124116 "WAP four-disulfide core domain 3" Q8IUB2 20 45747944-45791932 "Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "skin 1: 15.9;testis: 19.4" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 57.2;Early spermatids: 97.6;Late primary spermatocytes: 288.5;Late spermatids: 350.6;Rod photoreceptor cells: 131.0;Salivary ionocytes: 55.7" "Cell type enriched" "Detected in many" 5 "ependymal cell: 44.9" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Minor Salivary Gland - Minor salivary glandular cells, Skin - Eccrine sweat gland cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted in male reproductive system" "Enzyme inhibitor" NA NA "Cluster 47: Testis - Mixed function" "Cluster 46: Brainstem - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 2 "unprognostic (3.96e-1)" "unprognostic (9.22e-2)" "unprognostic (2.31e-1)" "potential prognostic unfavorable (1.53e-4)" "unprognostic (1.12e-2)" WFDC5 "dJ211D12.5, WAP1" ENSG00000175121 "WAP four-disulfide core domain 5" Q8TCV5 20 45109452-45115174 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 30 "skin 1: 376.0" "Group enriched" "Detected in some" 5 "Basal keratinocytes: 46.0;Early spermatids: 25.1;Late spermatids: 17.9;Suprabasal keratinocytes: 29.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 27.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "cervical cancer: 1.6;head and neck cancer: 5.0" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" "Enzyme inhibitor" NA NA "Cluster 37: Skin - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 26: Keratinocytes - Keratinization" 4 "unprognostic (2.95e-2)" "unprognostic (2.75e-2)" "unprognostic (1.27e-1)" "potential prognostic unfavorable (3.42e-8)" "unprognostic (3.61e-3)" "potential prognostic favorable (4.19e-5)" "unprognostic (4.89e-2)" "unprognostic (9.05e-2)" "unprognostic (5.43e-2)" "unprognostic (1.02e-1)" "unprognostic (2.45e-1)" WFDC6 "C20orf171, dJ461P17.11, WAP6" ENSG00000243543 "WAP four-disulfide core domain 6" Q9BQY6 20 45534196-45539482 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "epididymis: 210.1" "Cell type enhanced" "Detected in single" "Conjunctival goblet cells: 1.9" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Breast Invasive Carcinoma (TCGA): 1.3;Uterine Corpus Endometrial Carcinoma (TCGA): 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Skin - Sebaceous gland cells" "Secreted in male reproductive system" "Enzyme inhibitor" NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 38: Secretory epithelial cells - Exocrine secretion" "unprognostic (1.12e-2)" "unprognostic (1.32e-1)" "unprognostic (1.60e-1)" "unprognostic (5.59e-1)" WFDC8 "C20orf170, dJ461P17.1, WAP8" ENSG00000158901 "WAP four-disulfide core domain 8" Q8IUA0 20 45551153-45579326 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 517 "epididymis: 387.3" "Cell type enriched" "Detected in some" 27 "Epididymal principal cells: 529.2" "Cell type enhanced" "Detected in single" "mammillary body: 1.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA042710, HPA071119" Enhanced "Secreted in male reproductive system" "Enzyme inhibitor" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 9: Non-specific - Receptor signaling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" "HPA042710: , HPA071119: " WFDC9 "dJ688G8.2, WAP9" ENSG00000180205 "WAP four-disulfide core domain 9" Q8NEX5 20 45607939-45631284 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 455 "epididymis: 933.0" "Cell type enriched" "Detected in some" 98 "Epididymal principal cells: 1412.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" 1 WFIKKN1 "C16orf12, RJD2, WFDC20A, WFIKKN" ENSG00000127578 "WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1" Q96NZ8 16 629239-634117 "Predicted secreted proteins" "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.0" "Cell type enhanced" "Detected in many" "Foveolar cells: 6.0;Medullary thymic epithelial cells: 9.6;Respiratory ionocytes: 5.1;Retinal horizontal cells: 8.0;Thymic myoid cells: 13.6" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in single" "Testicular Germ Cell Tumor (TCGA): 1.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Rhabdoid: 2.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted in other tissues" "Enzyme inhibitor" NA NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 15: Non-specific - Transcription" "Cluster 34: Testis cancer - Unknown function" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 2 "unprognostic (2.41e-2)" "unprognostic (3.21e-2)" "unprognostic (4.15e-1)" WFIKKN2 "WFDC20B, WFIKKNRP" ENSG00000173714 "WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2" Q8TEU8 17 50834650-50842353 "Predicted intracellular proteins, Predicted secreted proteins" "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "choroid plexus: 1103.3" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 4.0;Granulosa cells: 6.5;Leydig cells: 9.3;Oocytes: 9.2;Ovarian stromal cells: 22.0;Peritubular myoid cells: 22.1;Thymic myoid cells: 2.7" "Cell type enriched" "Detected in some" 6 "choroid plexus epithelial cell: 21.4" "Cancer enriched" "Detected in some" 4 "Testicular Germ Cell Tumor (TCGA): 4.3" "Region enriched" "Detected in all" 71 "choroid plexus: 1253.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "Brain cancer: 3.0;Neuroblastoma: 4.5" "Colon - Enteric glia cells" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "medulla oblongata: 15.1;midbrain: 6.2;thalamus: 7.4" "Secreted in other tissues" "Enzyme inhibitor" NA NA 11000000 "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 94: Gonadal somatic cells - Mixed function" "unprognostic (9.91e-2)" "unprognostic (4.33e-2)" "unprognostic (2.27e-1)" WFS1 "DFNA14, DFNA38, DFNA6, DIDMOAD, WFS" ENSG00000109501 "Wolframin ER transmembrane glycoprotein" O76024 4 6269849-6303265 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cataract, Deafness, Diabetes insipidus, Diabetes mellitus, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 170.6;Extravillous trophoblasts: 175.4;Lymphatic endothelial cells: 117.4;Somatotrophs: 83.8" "Cell type enhanced" "Detected in all" "astrocyte: 86.9;eccentric medium spiny neuron: 81.8;ependymal cell: 79.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 1, Prostate - Smooth muscle cells, Stomach - Fibroblasts, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029128 Approved NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 19: Astrocytes - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 340 "HPA029128: " "unprognostic (2.27e-2)" "unprognostic (1.47e-2)" "unprognostic (8.98e-2)" "unprognostic (3.77e-2)" "unprognostic (8.14e-2)" "unprognostic (1.48e-2)" "unprognostic (1.46e-1)" "unprognostic (1.44e-1)" "unprognostic (3.75e-2)" "unprognostic (5.69e-2)" "unprognostic (7.27e-3)" "unprognostic (1.02e-1)" "unprognostic (2.85e-2)" "unprognostic (4.31e-2)" "unprognostic (1.52e-2)" "unprognostic (7.41e-2)" "unprognostic (3.79e-1)" "potential prognostic unfavorable (4.48e-4)" "unprognostic (2.86e-1)" "unprognostic (9.21e-2)" "unprognostic (1.38e-1)" "unprognostic (2.91e-2)" "unprognostic (3.87e-2)" "unprognostic (4.44e-3)" "unprognostic (2.00e-1)" "unprognostic (4.85e-2)" "unprognostic (1.58e-1)" "unprognostic (5.65e-2)" "unprognostic (2.75e-2)" "unprognostic (4.63e-3)" "unprognostic (1.88e-2)" WHAMM "KIAA1971, WHAMM1, WHDC1" ENSG00000156232 "WASP homolog associated with actin, golgi membranes and microtubules" Q8TF30 15 82809628-82836108 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 29.4" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039690, HPA040231" Approved Supported Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 58: Non-specific - Nuclear processes" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 1 Cytosol "HPA039690: , HPA040231: " "unprognostic (9.40e-2)" "unprognostic (9.41e-2)" "unprognostic (6.76e-2)" "unprognostic (1.72e-1)" "unprognostic (8.52e-2)" "unprognostic (1.17e-1)" "unprognostic (2.48e-1)" "unprognostic (2.04e-1)" "unprognostic (1.44e-2)" "unprognostic (4.08e-2)" "unprognostic (1.72e-1)" "unprognostic (1.16e-3)" "unprognostic (3.42e-3)" "unprognostic (8.44e-2)" "unprognostic (2.74e-1)" "unprognostic (2.78e-2)" "unprognostic (8.05e-2)" "unprognostic (1.91e-2)" "unprognostic (1.80e-1)" "unprognostic (1.57e-1)" "unprognostic (2.08e-1)" "unprognostic (3.24e-1)" "unprognostic (7.04e-2)" "potential prognostic unfavorable (4.53e-4)" "unprognostic (7.58e-2)" "unprognostic (3.45e-2)" "unprognostic (7.68e-2)" "unprognostic (8.36e-2)" "unprognostic (4.52e-2)" "unprognostic (1.43e-1)" "unprognostic (8.72e-2)" WHRN "CIP98, DFNB31, PDZD7B, USH2D" ENSG00000095397 Whirlin Q9P202 9 114402080-114505473 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Hearing "Deafness, Non-syndromic deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 121.0" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 370.8;Choroid plexus epithelial cells: 267.6;Gonadotrophs: 187.7;Late spermatids: 280.5;Sertoli cells: 201.5" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 179.6;oligodendrocyte: 162.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Myeloma: 61.9" "Adipose visceral - Mesothelial cells, Heart muscle - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB080582 Approved NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 18: Adrenal cortex cells - Steroidogensis" 9 "CAB080582: " "unprognostic (1.34e-1)" "unprognostic (2.46e-2)" "unprognostic (1.69e-1)" "unprognostic (1.71e-1)" "unprognostic (2.68e-1)" "unprognostic (2.33e-1)" "unprognostic (2.74e-2)" "unprognostic (2.36e-1)" "unprognostic (8.82e-2)" "unprognostic (8.51e-3)" "unprognostic (1.57e-1)" "unprognostic (5.78e-2)" "unprognostic (2.21e-2)" "unprognostic (3.57e-1)" "unprognostic (9.04e-2)" "unprognostic (2.78e-2)" "unprognostic (2.70e-1)" "unprognostic (6.51e-2)" "unprognostic (2.46e-2)" "potential prognostic favorable (2.25e-4)" "unprognostic (1.14e-2)" "unprognostic (8.97e-2)" "unprognostic (1.51e-1)" "unprognostic (3.18e-3)" "unprognostic (2.83e-2)" "unprognostic (2.46e-2)" "unprognostic (4.64e-1)" "unprognostic (7.19e-3)" "unprognostic (9.84e-3)" WIF1 ENSG00000156076 "WNT inhibitory factor 1" Q9Y5W5 12 65050626-65121305 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "retina: 555.8" "Cell type enriched" "Detected in many" 4 "Müller glia: 3967.5" "Cell type enhanced" "Detected in many" "astrocyte: 144.6;Bergmann glia: 99.0;MGE interneuron: 65.9" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 30.7;Uterine Corpus Endometrial Carcinoma (TCGA): 29.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "Rhabdoid: 16.6;Uterine cancer: 22.3" "Breast - Breast glandular cells, Lung - Alveolar cells type 2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 32: Non-specific - Cell proliferation" "Cluster 11: Muller glia cells - Retinal homeostasis" 91 "unprognostic (4.77e-2)" "unprognostic (1.67e-2)" "unprognostic (2.15e-2)" "unprognostic (5.13e-2)" "unprognostic (4.87e-2)" "unprognostic (2.92e-1)" "unprognostic (2.02e-2)" "unprognostic (2.74e-1)" "unprognostic (1.58e-1)" "unprognostic (1.57e-1)" "unprognostic (1.60e-2)" "unprognostic (5.38e-3)" "unprognostic (4.25e-1)" "unprognostic (4.65e-2)" "unprognostic (1.44e-1)" "unprognostic (3.03e-1)" "unprognostic (4.43e-2)" "unprognostic (5.53e-2)" "unprognostic (4.07e-1)" "unprognostic (2.07e-1)" "unprognostic (3.66e-1)" "potential prognostic favorable (6.01e-5)" WIPF1 "WASPIP, WIP" ENSG00000115935 "WAS/WASL interacting protein family member 1" O43516 2 174559572-174682916 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 107.0" "Cell type enhanced" "Detected in many" "B-cells: 338.5;Microglia: 323.4;monocytes: 357.4;Neutrophil progenitors: 473.6;Neutrophils: 1271.5;NK-cells: 493.1;Platelets: 898.7;T-cells: 468.9" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 424.4;committed oligodendrocyte precursor: 436.2;leukocyte: 563.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "lymphoma: 125.3;Myeloma: 104.8" "Breast - Fibroblasts, Colon - Enteric glia cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "HPA003739, CAB009737, HPA070706" Enhanced Approved "Plasma membrane,Cytosol" No No 460000 "Cluster 35: Neutrophils - Protein binding" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 30: White matter - Myelination" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 26 Cytosol "Plasma membrane" "CAB009737: , HPA003739: , HPA070706: " "unprognostic (1.47e-2)" "unprognostic (3.18e-2)" "unprognostic (1.29e-1)" "unprognostic (1.82e-1)" "unprognostic (6.49e-2)" "unprognostic (2.26e-1)" "unprognostic (3.10e-1)" "unprognostic (3.08e-1)" "unprognostic (3.80e-3)" "unprognostic (1.97e-3)" "unprognostic (6.50e-3)" "unprognostic (1.02e-1)" "unprognostic (5.65e-2)" "unprognostic (1.71e-1)" "unprognostic (8.64e-2)" "unprognostic (4.29e-2)" "unprognostic (6.25e-2)" "unprognostic (2.39e-1)" "unprognostic (4.10e-2)" "unprognostic (2.38e-2)" "unprognostic (1.13e-2)" "unprognostic (1.10e-1)" "unprognostic (5.38e-2)" "unprognostic (1.75e-1)" "unprognostic (4.56e-1)" "unprognostic (1.90e-1)" "unprognostic (5.19e-2)" "unprognostic (3.72e-2)" "unprognostic (6.97e-2)" "unprognostic (4.87e-1)" "unprognostic (5.59e-2)" WIPF2 "WICH, WIRE" ENSG00000171475 "WAS/WASL interacting protein family member 2" Q8TF74 17 40219304-40284136 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 391.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024000, HPA024001, HPA024467" Enhanced NA NA "Cluster 41: Basophils - Unknown function" "Cluster 73: Brain - Neuronal signaling" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Breast cancer - Unknown function" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 20 "HPA024000: , HPA024001: , HPA024467: " "unprognostic (7.00e-2)" "unprognostic (1.09e-1)" "unprognostic (1.16e-1)" "unprognostic (1.55e-3)" "unprognostic (1.79e-1)" "unprognostic (5.03e-3)" "unprognostic (1.07e-1)" "unprognostic (4.78e-1)" "unprognostic (3.62e-1)" "potential prognostic unfavorable (9.34e-4)" "potential prognostic favorable (2.49e-6)" "unprognostic (1.33e-3)" "unprognostic (3.16e-1)" "unprognostic (9.76e-3)" "unprognostic (1.07e-2)" "unprognostic (1.18e-1)" "unprognostic (1.61e-1)" "unprognostic (2.00e-1)" "unprognostic (5.56e-2)" "unprognostic (5.99e-2)" "unprognostic (2.12e-2)" "unprognostic (1.27e-3)" "unprognostic (1.27e-2)" "unprognostic (3.32e-1)" "unprognostic (3.05e-3)" "unprognostic (1.25e-1)" "unprognostic (1.20e-1)" "unprognostic (1.20e-1)" "unprognostic (2.81e-1)" "unprognostic (1.23e-1)" "unprognostic (4.04e-2)" WIPF3 "CR16, FLJ36931" ENSG00000122574 "WAS/WASL interacting protein family member 3" A6NGB9 7 29806486-29917061 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Actin-binding, Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 37.3;ovary: 57.4" "Cell type enhanced" "Detected in many" "Granulosa cells: 597.7;Myonuclei: 321.1;Ovarian stromal cells: 121.3;Peritubular myoid cells: 186.3;Podocytes: 527.8;Sertoli cells: 492.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Smooth muscle cells, Breast - Breast myoepithelial cells, Kidney - Podocytes, Prostate - Smooth muscle cells, Stomach - Parietal cells, Testis - Sertoli cells, Thyroid gland - Fibroblasts" "Region enhanced" "Detected in all" "hippocampal formation: 214.0" "Region enhanced" "Detected in all" "hippocampal formation: 173.5" "HPA041145, HPA041211" Uncertain Uncertain Mitochondria NA NA "Cluster 75: Ovary - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 55: Myocytes - Oxidative muscle function" 10 Mitochondria "HPA041145: , HPA041211: " "unprognostic (2.05e-1)" "unprognostic (1.83e-2)" "unprognostic (4.09e-1)" "unprognostic (7.53e-2)" "unprognostic (2.89e-1)" "unprognostic (2.20e-2)" "unprognostic (5.39e-3)" "unprognostic (2.19e-1)" "unprognostic (2.24e-1)" "unprognostic (2.59e-3)" "unprognostic (3.74e-2)" "unprognostic (2.30e-1)" "unprognostic (1.97e-2)" "unprognostic (3.99e-2)" "unprognostic (7.56e-2)" "unprognostic (3.06e-3)" "unprognostic (1.48e-1)" "unprognostic (2.46e-2)" "unprognostic (4.85e-2)" "unprognostic (9.80e-3)" "unprognostic (2.48e-3)" "unprognostic (1.03e-1)" "unprognostic (5.26e-2)" "unprognostic (4.47e-2)" "unprognostic (1.31e-1)" "unprognostic (2.06e-1)" "unprognostic (6.52e-3)" "unprognostic (1.26e-1)" "unprognostic (1.08e-2)" WIPI1 "ATG18, ATG18A, FLJ10055, WIPI49" ENSG00000070540 "WD repeat domain, phosphoinositide interacting 1" Q5MNZ9 17 68420948-68457513 "Predicted intracellular proteins" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 119.2" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 294.7;Platelets: 211.7;Respiratory secretory cells: 203.6;Syncytiotrophoblasts: 223.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 114.9;eosinophil: 224.2" "Lineage enriched" "Detected in all" 9 "granulocytes: 224.2" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007493, CAB037230" Enhanced Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 48: Neutrophils - Phagocytosis & degranulation" "Golgi apparatus" "Nucleoplasm, Cytosol" "CAB037230: , HPA007493: " "unprognostic (2.71e-1)" "unprognostic (1.18e-1)" "unprognostic (6.95e-2)" "unprognostic (2.26e-1)" "unprognostic (2.47e-2)" "unprognostic (1.00e-1)" "unprognostic (2.19e-2)" "potential prognostic unfavorable (4.90e-4)" "unprognostic (7.98e-2)" "unprognostic (2.16e-3)" "unprognostic (8.40e-2)" "unprognostic (4.50e-2)" "potential prognostic favorable (3.69e-4)" "unprognostic (3.10e-3)" "unprognostic (5.60e-3)" "unprognostic (3.41e-1)" "unprognostic (3.27e-2)" "unprognostic (9.55e-2)" "unprognostic (1.38e-1)" "unprognostic (2.65e-1)" "unprognostic (7.09e-2)" "unprognostic (1.05e-1)" "unprognostic (2.53e-1)" "unprognostic (3.73e-1)" "unprognostic (1.37e-1)" "unprognostic (1.15e-1)" "unprognostic (3.64e-2)" "unprognostic (3.51e-3)" "unprognostic (1.23e-1)" "unprognostic (4.90e-2)" "unprognostic (1.43e-1)" WIPI2 "ATG18B, ATG21, CGI-50, DKFZP434J154, DKFZp686P02188, FLJ12979, FLJ14217, FLJ42984" ENSG00000157954 "WD repeat domain, phosphoinositide interacting 2" Q9Y4P8 7 5190196-5233840 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Autophagy "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 254.5;Late primary spermatocytes: 285.6;Late spermatids: 302.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019852, HPA021488" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 67: Non-specific - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 13 Cytosol Nucleoplasm "HPA019852: , HPA021488: " "unprognostic (6.85e-3)" "potential prognostic unfavorable (5.38e-4)" "unprognostic (1.88e-2)" "unprognostic (8.78e-3)" "unprognostic (5.16e-2)" "unprognostic (6.48e-2)" "unprognostic (6.02e-3)" "unprognostic (9.60e-2)" "unprognostic (5.54e-3)" "unprognostic (1.51e-1)" "potential prognostic favorable (1.96e-5)" "unprognostic (1.16e-1)" "unprognostic (1.20e-1)" "unprognostic (1.87e-3)" "unprognostic (1.45e-2)" "unprognostic (8.76e-3)" "unprognostic (2.62e-2)" "unprognostic (1.90e-1)" "unprognostic (2.72e-2)" "unprognostic (2.74e-1)" "unprognostic (2.18e-2)" "unprognostic (6.56e-2)" "unprognostic (9.70e-2)" "unprognostic (3.48e-1)" "unprognostic (3.67e-2)" "unprognostic (8.26e-2)" "unprognostic (1.04e-1)" "unprognostic (5.03e-3)" "unprognostic (9.31e-2)" "unprognostic (8.14e-2)" "unprognostic (1.37e-2)" WIZ ZNF803 ENSG00000011451 "WIZ zinc finger" O95785 19 15419978-15449956 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022923, HPA023774" Supported Enhanced Nucleoplasm NA No "Cluster 74: Non-specific - Signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 48 Nucleoplasm "HPA022923: , HPA023774: " "unprognostic (8.13e-2)" "unprognostic (1.13e-1)" "unprognostic (1.08e-1)" "unprognostic (7.60e-2)" "unprognostic (1.11e-1)" "unprognostic (1.88e-1)" "unprognostic (4.21e-1)" "unprognostic (3.92e-1)" "unprognostic (4.03e-2)" "unprognostic (8.18e-2)" "unprognostic (5.95e-2)" "unprognostic (2.37e-1)" "unprognostic (2.77e-1)" "unprognostic (1.93e-3)" "unprognostic (4.59e-2)" "unprognostic (3.95e-2)" "unprognostic (1.93e-1)" "unprognostic (2.21e-2)" "unprognostic (7.16e-3)" "unprognostic (2.12e-2)" "unprognostic (6.73e-2)" "unprognostic (2.64e-1)" "unprognostic (4.25e-3)" "unprognostic (1.92e-2)" "unprognostic (1.62e-1)" "potential prognostic favorable (4.74e-5)" "unprognostic (7.03e-3)" "unprognostic (7.09e-2)" "unprognostic (7.94e-2)" "unprognostic (1.63e-2)" "unprognostic (6.51e-2)" WLS "C1orf139, EVI, FLJ23091, GPR177, mig-14, MRP" ENSG00000116729 "Wnt ligand secretion mediator" Q5T9L3 1 68098473-68233120 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial luminal cells: 551.5;Ependymal cells: 405.5;Neutrophils: 375.8" "Cell type enhanced" "Detected in all" "ependymal cell: 529.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "classical monocyte: 22.1;neutrophil: 62.1" "Group enriched" "Detected in many" 46 "granulocytes: 62.1;monocytes: 22.1" "Cancer enhanced" "Detected in many" "testis cancer: 329.0" "Breast - Breast myoepithelial cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069520 Approved Approved "Endoplasmic reticulum,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" 14 "Endoplasmic reticulum, Cytosol" "HPA069520: " "unprognostic (7.89e-2)" "unprognostic (9.55e-3)" "unprognostic (8.03e-2)" "unprognostic (1.60e-2)" "unprognostic (9.56e-3)" "unprognostic (9.18e-2)" "unprognostic (4.51e-2)" "unprognostic (3.94e-2)" "unprognostic (8.90e-3)" "unprognostic (3.99e-1)" "potential prognostic favorable (3.21e-11)" "unprognostic (3.99e-3)" "unprognostic (8.41e-2)" "unprognostic (6.74e-3)" "unprognostic (1.61e-2)" "unprognostic (4.47e-2)" "unprognostic (1.06e-2)" "unprognostic (5.80e-2)" "unprognostic (7.34e-2)" "unprognostic (2.95e-2)" "unprognostic (3.66e-2)" "unprognostic (5.71e-2)" "unprognostic (4.43e-2)" "unprognostic (1.53e-1)" "unprognostic (1.12e-1)" "unprognostic (2.89e-2)" "unprognostic (3.23e-2)" "unprognostic (2.58e-2)" "unprognostic (1.22e-1)" "unprognostic (1.51e-2)" "unprognostic (1.89e-1)" WNK1 "HSAN2, HSN2, PPP1R167, PRKWNK1" ENSG00000060237 "WNK lysine deficient protein kinase 1" Q9H4A3 12 752579-911452 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal convoluted tubule cells: 1795.8;Esophageal apical cells: 826.4;Renal connecting tubule cells: 892.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Kidney - Intercalated cells, Lung - Alveolar cells type 1, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046541, HPA059157" Enhanced Supported Cytosol NA NA 22000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 6: Non-specific - Immune response" "Cluster 38: Non-specific - Transcription" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 55 Cytosol "HPA046541: , HPA059157: " "unprognostic (1.40e-1)" "unprognostic (3.82e-2)" "unprognostic (2.25e-1)" "unprognostic (4.49e-2)" "unprognostic (1.94e-1)" "unprognostic (7.01e-3)" "unprognostic (7.05e-2)" "unprognostic (2.82e-1)" "unprognostic (6.52e-2)" "unprognostic (3.06e-2)" "unprognostic (3.70e-3)" "unprognostic (1.22e-1)" "unprognostic (1.13e-1)" "potential prognostic unfavorable (6.78e-4)" "unprognostic (3.23e-3)" "unprognostic (2.29e-2)" "unprognostic (1.40e-1)" "unprognostic (1.36e-1)" "unprognostic (1.34e-2)" "unprognostic (4.55e-3)" "unprognostic (8.02e-2)" "unprognostic (1.56e-1)" "unprognostic (2.43e-3)" "unprognostic (1.28e-1)" "unprognostic (6.98e-2)" "unprognostic (1.01e-3)" "unprognostic (9.40e-2)" "unprognostic (1.20e-1)" "unprognostic (1.10e-1)" "unprognostic (9.03e-2)" "unprognostic (2.83e-1)" WNK2 "KIAA1760, NY-CO-43, PRKWNK2, SDCCAG43" ENSG00000165238 "WNK lysine deficient protein kinase 2" Q9Y3S1 9 93184122-93320572 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 63.5" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 320.7;Cone photoreceptor cells: 474.1;Lacrimal acinar cells: 302.5;Lactotrophs: 352.7;Pituitary stem cells: 350.8;Rod photoreceptor cells: 454.5;Somatotrophs: 377.0;Thyrotrophs: 448.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Prostate - Prostate basal glandular cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015555, HPA016519, CAB017813" Enhanced Approved Cytosol NA NA "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 79: Photoreceptor cells - Phototransduction" 13 Cytosol "CAB017813: , HPA015555: , HPA016519: " "unprognostic (3.57e-1)" "unprognostic (7.99e-2)" "unprognostic (7.77e-2)" "unprognostic (5.53e-2)" "unprognostic (2.11e-1)" "unprognostic (2.52e-1)" "unprognostic (2.11e-1)" "unprognostic (2.60e-3)" "unprognostic (9.77e-2)" "unprognostic (2.25e-1)" "unprognostic (2.23e-1)" "unprognostic (4.39e-2)" "unprognostic (6.19e-2)" "unprognostic (1.72e-1)" "potential prognostic favorable (1.21e-4)" "unprognostic (1.89e-2)" "unprognostic (7.10e-2)" "unprognostic (7.48e-2)" "unprognostic (2.75e-2)" "unprognostic (1.73e-1)" "unprognostic (1.29e-1)" "unprognostic (2.03e-2)" "unprognostic (1.17e-1)" "unprognostic (1.61e-1)" "unprognostic (1.54e-1)" "unprognostic (1.12e-1)" "unprognostic (1.04e-2)" WNK3 PRKWNK3 ENSG00000196632 "WNK lysine deficient protein kinase 3" Q9BYP7 X 54192823-54358642 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 11.1;testis: 9.2" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 218.3;Erythrocyte progenitors: 189.7;Gonadotrophs: 317.1;Mast cells: 159.7;Sertoli cells: 724.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 3.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Pituitary gland - Gonadotropes, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077678 Approved Approved Vesicles NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 11 Vesicles "HPA077678: " "unprognostic (2.00e-1)" "unprognostic (1.40e-2)" "unprognostic (1.18e-2)" "potential prognostic favorable (1.19e-4)" "potential prognostic unfavorable (8.80e-4)" "unprognostic (2.20e-2)" "potential prognostic favorable (6.19e-5)" "unprognostic (1.14e-1)" "unprognostic (1.81e-1)" WNK4 PRKWNK4 ENSG00000126562 "WNK lysine deficient protein kinase 4" Q96J92 17 42780610-42797066 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 41.5;prostate: 13.8" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 246.1;Enteric stem cells: 33.5;Esophageal apical cells: 32.3;Esophageal suprabasal cells: 47.0;Goblet cells: 115.9;Loop of henle epithelial cells: 107.7;Pituicytes/FSCs: 41.9;Prostatic glandular cells: 44.5;Renal connecting tubule cells: 58.5;Tuft cells: 34.6" "Group enriched" "Detected in some" 9 "fibroblast: 11.1;hippocampal CA4: 15.2;hippocampal dentate gyrus: 29.3" "Group enriched" "Detected in many" 4 "Breast Invasive Carcinoma (TCGA): 15.3;Colon Adenocarcinoma (TCGA): 19.4;Prostate Adenocarcinoma (TCGA): 20.6;Rectum Adenocarcinoma (TCGA): 19.3;Skin Cutaneous Melanoma (TCGA): 9.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Kidney - Ascending Loop of Henle cells, Pancreas - Alpha cells, Prostate - Prostate glandular cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Stomach - Parietal cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA016500 Approved NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 47: Endothelial cells - Vasculature" "Cluster 27: Breast cancer - Unknown function" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 6 "HPA016500: " "unprognostic (7.52e-3)" "unprognostic (3.51e-2)" "unprognostic (2.73e-2)" "unprognostic (1.24e-1)" "unprognostic (1.93e-1)" "unprognostic (1.41e-1)" "unprognostic (1.67e-1)" "unprognostic (2.47e-1)" "unprognostic (3.57e-2)" "unprognostic (1.11e-1)" "unprognostic (2.52e-1)" "unprognostic (3.47e-1)" "unprognostic (6.44e-2)" "potential prognostic favorable (9.58e-4)" "unprognostic (7.87e-2)" "unprognostic (2.78e-2)" "unprognostic (2.53e-2)" "unprognostic (1.65e-2)" "unprognostic (7.15e-2)" "unprognostic (2.26e-1)" "unprognostic (1.89e-1)" WNT1 INT1 ENSG00000125084 "Wnt family member 1" P04628 12 48978322-48982620 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Cancer-related genes, Disease variant, Osteogenesis imperfecta, Osteoporosis, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "testis: 1.2" "Cell type enhanced" "Detected in some" "cDC: 1.3;Differentiating spermatogonia: 1.6;Early primary spermatocytes: 7.5;Epicardial cells: 4.5;Extravillous trophoblasts: 5.4;Late primary spermatocytes: 2.3;NK-cells: 1.9;Platelets: 1.4;T-cells: 3.3" "Cell type enhanced" "Detected in single" "leukocyte: 2.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 8 "gdT-cell: 3.1;MAIT T-cell: 5.1;memory CD4 T-cell: 2.0;memory CD8 T-cell: 2.9;naive CD8 T-cell: 2.1" "Lineage enriched" "Detected in single" 32 "T-cells: 5.1" "Cancer enriched" "Detected in single" 26 "ovarian cancer: 10.0" "Lung - T-cells, Prostate - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 33: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 9: T-cells - Adaptive immunity: Regulation" WNT10A ENSG00000135925 "Wnt family member 10A" Q9GZT5 2 218880852-218899581 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Disease variant, Ectodermal dysplasia, Hypotrichosis, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 7.9;skin 1: 8.4" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 27.4;Epididymal basal cells: 17.0;Esophageal basal cells: 25.7;Fallopian secretory cells: 10.8;pDCs: 51.5;Plasma cells: 28.7;Retinal bipolar cells: 11.4" "Cell type enhanced" "Detected in many" "medium spiny neuron: 9.5" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 41.2" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 6 "plasmacytoid DC: 6.2" "Lineage enriched" "Detected in many" 6 "dendritic cells: 6.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 38.9" "Adipose visceral - Mesothelial cells, Stomach - Plasma cells, Testis - Early spermatids" "Region enhanced" "Detected in many" "cerebral cortex: 5.2" "Region enhanced" "Detected in some" "basal ganglia: 3.2" HPA013898 Uncertain "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 58: Skin - Keratinization" "Cluster 33: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 67: Plasma cells - Plasma cell differentiation" 21 "HPA013898: " "unprognostic (1.12e-1)" "unprognostic (2.18e-3)" "unprognostic (2.11e-1)" "unprognostic (3.78e-2)" "unprognostic (9.28e-2)" "unprognostic (1.33e-1)" "unprognostic (2.15e-1)" "unprognostic (9.99e-2)" "unprognostic (4.33e-3)" "unprognostic (9.29e-2)" "unprognostic (4.40e-2)" "unprognostic (4.51e-2)" "unprognostic (2.84e-1)" "unprognostic (3.98e-2)" "unprognostic (1.68e-2)" "unprognostic (8.19e-2)" "unprognostic (7.00e-2)" "unprognostic (1.87e-2)" "unprognostic (2.21e-3)" "potential prognostic unfavorable (8.80e-4)" "unprognostic (5.82e-2)" "unprognostic (7.76e-3)" "unprognostic (1.67e-1)" "unprognostic (5.24e-2)" "unprognostic (8.22e-2)" "unprognostic (1.33e-1)" "unprognostic (1.36e-2)" "unprognostic (1.14e-1)" WNT10B "SHFM6, WNT-12" ENSG00000169884 "Wnt family member 10B" O00744 12 48965340-48971735 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 39.1" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 9.3;Brain inhibitory neurons: 15.6;Early primary spermatocytes: 5.0;Extravillous trophoblasts: 31.3;Fibro-adipogenic progenitors: 8.1;Fibroblasts: 5.3;Hepatic stellate cells: 6.5;Other brain neurons: 5.0;Pituitary stem cells: 6.7;T-cells: 3.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 18.6" "Breast - T-cells, Kidney - T-cells, Prostate - T-cells, Thyroid gland - T-cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA055048, HPA062539" Enhanced Approved "Golgi apparatus" "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 35: Neurons - Synaptic function & neurogenesis" 9 "Golgi apparatus" "HPA055048: , HPA062539: " "unprognostic (6.47e-2)" "unprognostic (1.60e-1)" "unprognostic (1.13e-2)" "unprognostic (8.13e-2)" "unprognostic (2.48e-2)" "unprognostic (1.82e-1)" "unprognostic (1.03e-1)" "unprognostic (2.43e-1)" "unprognostic (2.31e-1)" WNT11 ENSG00000085741 "Wnt family member 11" O96014 11 76186325-76210736 "Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 35.7" "Cell type enhanced" "Detected in some" "Adipocytes: 9.4;Adrenal cortex cells: 14.3;Cardiomyocytes: 9.6;Choroid plexus epithelial cells: 9.2;Fibro-adipogenic progenitors: 34.9;Fibroblasts: 17.2;Megakaryocytes: 12.4;Platelets: 25.4" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 5.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "NK-cell: 2.9" "Lineage enriched" "Detected in single" 6 "NK-cells: 2.9" "Cancer enhanced" "Detected in many" "colorectal cancer: 27.9" "Breast - Endothelial cells, Kidney - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA050101 Uncertain "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 44: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 108: Fibroblasts - ECM organization" 18 "HPA050101: " "unprognostic (1.98e-2)" "unprognostic (1.19e-3)" "unprognostic (8.14e-2)" "unprognostic (1.05e-2)" "unprognostic (1.66e-2)" "unprognostic (1.42e-1)" "unprognostic (7.88e-2)" "unprognostic (2.26e-2)" "unprognostic (5.35e-2)" "potential prognostic favorable (8.24e-4)" "potential prognostic favorable (2.33e-4)" "unprognostic (2.40e-2)" "unprognostic (1.27e-1)" "unprognostic (2.01e-2)" "unprognostic (1.76e-2)" "unprognostic (5.21e-2)" "unprognostic (1.80e-2)" "unprognostic (9.90e-2)" "unprognostic (9.75e-2)" "unprognostic (3.28e-2)" "unprognostic (1.52e-1)" "unprognostic (1.39e-1)" "unprognostic (5.03e-2)" "unprognostic (4.42e-1)" "unprognostic (3.36e-3)" "unprognostic (1.15e-1)" WNT16 ENSG00000002745 "Wnt family member 16" Q9UBV4 7 121325367-121341104 "Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "cervix: 6.4;skin 1: 19.4" "Cell type enhanced" "Detected in some" "B-cells: 11.9;Basal keratinocytes: 8.4;Corticotrophs: 6.1;Endometrial stromal cells: 5.5;Ependymal cells: 4.0;Epicardial cells: 6.8;Epididymal efferent duct absorptive cells: 3.5;Epididymal efferent duct ciliated cells: 24.3;Retinal ganglion cells: 3.9;Suprabasal keratinocytes: 8.2" "Group enriched" "Detected in some" 4 "ependymal cell: 9.1;fibroblast: 18.1;LAMP5-LHX6 and Chandelier: 9.4;MGE interneuron: 23.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 145 "memory B-cell: 15.6;naive B-cell: 15.5" "Lineage enriched" "Detected in single" 146 "B-cells: 15.6" "Cancer enhanced" "Detected in many" "Leukemia: 9.8" "Colon - Enteric glia cells, Skin - Keratinocyte (other), Spleen - B-cells (Spleen)" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 37: Skin - Keratinization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 87: B-cells - Adaptive immunity: Humoral response" "unprognostic (1.42e-3)" "potential prognostic unfavorable (2.43e-4)" "unprognostic (2.51e-3)" "unprognostic (3.13e-1)" "unprognostic (4.27e-2)" WNT2 "INT1L1, IRP" ENSG00000105989 "Wnt family member 2" P09544 7 117275451-117323152 "Cancer-related genes, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "placenta: 37.5" "Group enriched" "Detected in some" 12 "Decidual stromal cells: 124.6;Early spermatids: 58.3;Endometrial stromal cells: 33.5;Fibroblasts: 63.6;Late primary spermatocytes: 36.0;Late spermatids: 38.5;Pericytes: 44.8" "Group enriched" "Detected in some" 4 "hippocampal CA4: 5.7;thalamic excitatory: 13.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Rhabdoid: 2.7" "Adipose subcutaneous - Adipose progenitor cells, Colon - Fibroblasts, Liver - Sinusoid Endothelial cells, Prostate - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Region enhanced" "Detected in many" "basal ganglia: 12.6" "Low region specificity" "Detected in many" HPA020920 Approved Vesicles "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 7 Vesicles "HPA020920: " "unprognostic (8.88e-2)" "unprognostic (3.70e-1)" "unprognostic (1.63e-1)" "unprognostic (3.97e-2)" "unprognostic (4.42e-1)" "unprognostic (5.20e-3)" "unprognostic (1.29e-3)" "unprognostic (3.34e-1)" "unprognostic (1.61e-1)" "unprognostic (1.64e-1)" "unprognostic (2.78e-2)" "unprognostic (5.12e-1)" "unprognostic (2.25e-2)" "unprognostic (6.08e-3)" "unprognostic (4.25e-3)" "unprognostic (3.11e-1)" "unprognostic (3.56e-2)" "unprognostic (2.51e-2)" "unprognostic (1.07e-1)" WNT2B "WNT13, XWNT2" ENSG00000134245 "Wnt family member 2B" Q93097 1 112466541-112530165 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial secretory cells: 93.0;Leydig cells: 83.2;Microglia: 150.1;Peritubular myoid cells: 194.3;Vascular endothelial cells: 97.1" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 182.0" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 14.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Testis - Peritubular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA047274, HPA066368" Approved Nucleoplasm,Vesicles "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 58: Skin - Keratinization" "Cluster 53: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 1 Vesicles Nucleoplasm "HPA047274: , HPA066368: " "unprognostic (4.56e-3)" "unprognostic (1.63e-2)" "potential prognostic favorable (7.17e-4)" "unprognostic (2.22e-1)" "unprognostic (1.78e-1)" "unprognostic (2.18e-1)" "unprognostic (1.21e-1)" "unprognostic (2.00e-1)" "unprognostic (1.70e-1)" "unprognostic (1.13e-1)" "unprognostic (2.03e-1)" "unprognostic (2.66e-2)" "unprognostic (4.08e-1)" "unprognostic (9.47e-3)" "unprognostic (3.95e-2)" "unprognostic (1.51e-1)" "unprognostic (3.78e-1)" "unprognostic (3.48e-2)" "unprognostic (8.73e-2)" "unprognostic (5.71e-2)" "unprognostic (3.01e-3)" "unprognostic (2.73e-1)" "unprognostic (2.22e-1)" "unprognostic (1.90e-2)" "unprognostic (9.90e-2)" WNT3 "INT4, MGC131950, MGC138321, MGC138323" ENSG00000108379 "Wnt family member 3" P56703 17 46762506-46833154 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "liver: 12.0;skin 1: 26.7" "Cell type enhanced" "Detected in some" "Astrocytes: 10.4;Basal keratinocytes: 12.1;Bergmann glia: 57.6;Brain excitatory neurons: 8.5;Brain inhibitory neurons: 10.0;Early spermatids: 22.0;Late spermatids: 59.1;Other brain neurons: 9.9;Podocytes: 14.5" "Cell type enhanced" "Detected in many" "Bergmann glia: 57.0;thalamic excitatory: 44.7" "Cancer enriched" "Detected in many" 6 "Testicular Germ Cell Tumor (TCGA): 17.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA049893 Approved Vesicles "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 37: Skin - Keratinization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 98: Neurons - Neurotransmission & signaling" 2 Vesicles "HPA049893: " "unprognostic (2.87e-2)" "unprognostic (1.01e-1)" "unprognostic (1.55e-2)" "potential prognostic unfavorable (7.56e-4)" "unprognostic (2.83e-2)" "unprognostic (4.92e-1)" "unprognostic (3.81e-2)" "unprognostic (6.28e-2)" "unprognostic (7.58e-2)" "unprognostic (4.32e-2)" "unprognostic (4.49e-2)" "unprognostic (3.19e-1)" "unprognostic (1.65e-1)" "unprognostic (1.32e-1)" "unprognostic (2.01e-1)" "unprognostic (4.37e-3)" "unprognostic (1.84e-1)" "unprognostic (5.46e-2)" "unprognostic (4.93e-1)" "unprognostic (2.64e-2)" WNT3A ENSG00000154342 "Wnt family member 3A" P56704 1 228006998-228061271 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "placenta: 14.7" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 36.8;Basal keratinocytes: 7.7;Basal prostatic cells: 10.8;Pericytes: 9.2;Respiratory basal cells: 30.3;Respiratory secretory cells: 8.1;Salivary basal cells: 9.7;Salivary myoepithelial cells: 10.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Head and Neck Squamous Cell Carcinoma (TCGA): 3.0;Lung Squamous Cell Carcinoma (TCGA): 3.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 4.0;head and neck cancer: 2.9" "Breast - Breast myoepithelial cells, Lung - Alveolar cells type 1, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Not detected" "Not detected" HPA049893 Approved Vesicles "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 108: Fibroblasts - ECM organization" 7 Vesicles "HPA049893: " "potential prognostic favorable (2.02e-8)" "unprognostic (6.24e-2)" "unprognostic (3.37e-1)" WNT4 WNT-4 ENSG00000162552 "Wnt family member 4" P56705 1 22117313-22143969 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 38.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 33.4;Breast hormone-responsive cells: 52.5;Endometrial stromal cells: 63.5;Neuroendocrine cells: 30.5;Ocular epithelial cells: 54.5;Pancreatic islet cells: 224.2;Respiratory basal cells: 62.2;Salivary duct cells: 30.8;Suprabasal keratinocytes: 37.8" "Cell type enriched" "Detected in many" 8 "fibroblast: 77.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 9.8" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal cortex cells, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary gland basal cells, Pancreas - Alpha cells, Pituitary gland - Gonadotropes, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011397 Uncertain Approved Vesicles "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 58: Skin - Keratinization" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 2 Vesicles "HPA011397: " "unprognostic (2.02e-1)" "unprognostic (3.15e-1)" "unprognostic (2.01e-1)" "unprognostic (9.32e-2)" "potential prognostic favorable (4.32e-4)" "unprognostic (2.82e-1)" "unprognostic (4.51e-2)" "unprognostic (1.22e-2)" "unprognostic (9.94e-3)" "unprognostic (2.93e-2)" "unprognostic (1.46e-1)" "unprognostic (6.36e-2)" "unprognostic (2.67e-2)" "unprognostic (1.89e-1)" "unprognostic (9.92e-2)" "unprognostic (4.32e-1)" "potential prognostic favorable (2.39e-4)" "unprognostic (8.41e-2)" "unprognostic (1.46e-1)" "unprognostic (7.39e-2)" "unprognostic (3.71e-3)" "unprognostic (2.93e-3)" "unprognostic (2.61e-1)" "unprognostic (2.97e-1)" "unprognostic (3.44e-2)" "unprognostic (7.53e-2)" WNT5A hWNT5A ENSG00000114251 "Wnt family member 5A" P41221 3 55465715-55490539 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Wnt signaling pathway" "Developmental protein" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 25.7;salivary gland: 32.4" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 114.3;Esophageal apical cells: 90.6;Papillary tip epithelial cells: 117.8;Pituitary stem cells: 97.5;Prostatic club cells: 206.1;Prostatic hillock cells: 141.1;Salivary acinar cells: 80.9;Transitional alveolar cells: 59.5;Urothelial cells: 54.7" "Cell type enhanced" "Detected in many" "Bergmann glia: 54.8;central nervous system macrophage: 49.4;fibroblast: 72.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 91.1" "Kidney - Fibroblasts, Liver - Hepatocytes, Pituitary gland - Undifferentiated cells (Pituitary gland)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072252 Uncertain "Nucleoli fibrillar center,Microtubules,Mitotic spindle,Primary cilium" "Secreted to extracellular matrix" "Developmental protein" Yes NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 3 "Microtubules, Mitotic spindle, Primary cilium" "Nucleoli fibrillar center" "HPA072252: " "unprognostic (1.29e-1)" "unprognostic (3.73e-3)" "unprognostic (3.15e-1)" "unprognostic (1.40e-1)" "potential prognostic favorable (5.93e-4)" "unprognostic (1.46e-1)" "unprognostic (4.81e-2)" "unprognostic (5.65e-2)" "unprognostic (5.86e-2)" "unprognostic (1.63e-1)" "unprognostic (1.39e-3)" "unprognostic (3.33e-2)" "unprognostic (9.62e-3)" "unprognostic (2.26e-2)" "unprognostic (2.93e-1)" "unprognostic (4.48e-1)" "unprognostic (1.87e-1)" "unprognostic (1.95e-2)" "unprognostic (2.41e-2)" "unprognostic (1.40e-1)" "unprognostic (8.71e-2)" "unprognostic (4.07e-3)" "unprognostic (1.75e-1)" "unprognostic (9.07e-2)" "unprognostic (7.26e-2)" "unprognostic (2.82e-1)" "unprognostic (5.45e-2)" "unprognostic (4.38e-2)" "unprognostic (2.10e-1)" "unprognostic (2.36e-2)" "unprognostic (2.28e-1)" WNT5B ENSG00000111186 "Wnt family member 5B" Q9H1J7 12 1529891-1647212 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 31.6" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 217.3;Cone photoreceptor cells: 128.3;Lacrimal acinar cells: 120.5;Müller glia: 231.0;Plasma cells: 157.9;Prostatic club cells: 310.9;Prostatic glandular cells: 269.0;Prostatic hillock cells: 193.0;Salivary basal cells: 120.7;Salivary duct cells: 150.8;Submucosal glandular cells: 124.2" "Cell type enhanced" "Detected in all" "fibroblast: 107.2" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 46.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.8;eosinophil: 1.5" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 90.7" "Kidney - Fibroblasts, Liver - Hepatocytes, Skeletal muscle - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061991 Approved Vesicles "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 38: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 44: Plasma cells - Antibody production & secretion" Vesicles "HPA061991: " "unprognostic (4.97e-2)" "unprognostic (5.49e-2)" "unprognostic (3.65e-1)" "unprognostic (9.46e-2)" "unprognostic (2.38e-2)" "unprognostic (8.71e-2)" "unprognostic (7.83e-2)" "unprognostic (4.84e-2)" "unprognostic (2.96e-1)" "unprognostic (1.57e-1)" "unprognostic (2.51e-2)" "unprognostic (6.88e-3)" "unprognostic (3.47e-2)" "unprognostic (4.07e-3)" "potential prognostic favorable (2.56e-5)" "unprognostic (1.30e-1)" "unprognostic (1.02e-1)" "unprognostic (3.19e-2)" "unprognostic (1.24e-1)" "unprognostic (2.63e-2)" "unprognostic (1.21e-2)" "unprognostic (2.83e-2)" "unprognostic (1.01e-1)" "unprognostic (1.63e-2)" "unprognostic (1.39e-1)" "unprognostic (3.53e-1)" "unprognostic (1.64e-1)" "unprognostic (2.13e-2)" "unprognostic (1.62e-1)" "unprognostic (2.79e-1)" "unprognostic (2.19e-1)" WNT6 ENSG00000115596 "Wnt family member 6" Q9Y6F9 2 218859805-218874233 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 9.8" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 15.0;Breast myoepithelial cells: 22.4;Granulosa cells: 190.6;Hepatic stellate cells: 25.8;Late primary spermatocytes: 33.7;Migrating cytotrophoblasts: 29.2;Pericytes: 53.5;Schwann cells: 70.6" "Cell type enhanced" "Detected in some" "fibroblast: 14.3;pericyte: 38.8;vascular associated smooth muscle cell: 17.5" "Group enriched" "Detected in some" 4 "Bladder Urothelial Carcinoma (TCGA): 3.8;Ovary Serous Cystadenocarcinoma (TCGA): 12.2;Uterine Corpus Endometrial Carcinoma (TCGA): 4.1" "Group enriched" "Detected in many" 5 "basal ganglia: 20.5;thalamus: 5.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 10.2" HPA070759 Approved "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 68: Non-specific - Basic cellular processes" "Cluster 33: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 110: Mural cells - ECM organization" "HPA070759: " "unprognostic (1.71e-2)" "unprognostic (4.17e-2)" "unprognostic (3.77e-1)" "potential prognostic favorable (7.86e-5)" "unprognostic (2.56e-2)" "unprognostic (1.09e-1)" "unprognostic (1.73e-1)" "unprognostic (3.54e-1)" "unprognostic (1.04e-1)" WNT7A Wnt-7a ENSG00000154764 "Wnt family member 7A" O00755 3 13816258-13880071 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.9;gallbladder: 2.2;placenta: 2.5" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 44.2;Cytotrophoblasts: 87.9;Early spermatids: 23.0;Endometrial luminal cells: 40.1;Endometrial secretory cells: 22.7;Extravillous trophoblasts: 209.5;Migrating cytotrophoblasts: 76.6;Syncytiotrophoblasts: 218.7" "Cell type enhanced" "Detected in many" "astrocyte: 18.2;eccentric medium spiny neuron: 19.9;LAMP5-LHX6 and Chandelier: 18.9" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 17.4;Uterine Corpus Endometrial Carcinoma (TCGA): 30.7" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 7 "memory CD4 T-cell: 1.7;naive CD4 T-cell: 1.6" "Lineage enriched" "Detected in single" 18 "T-cells: 1.7" "Cancer enhanced" "Detected in many" "ovarian cancer: 23.8;Uterine cancer: 24.6" "Lung - Alveolar cells type 1, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015719, CAB025894" Approved "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 7 "CAB025894: , HPA015719: " "unprognostic (1.10e-2)" "unprognostic (1.19e-1)" "unprognostic (1.67e-1)" "unprognostic (1.40e-1)" "potential prognostic unfavorable (9.36e-4)" "unprognostic (3.58e-3)" "unprognostic (4.71e-3)" "unprognostic (2.45e-1)" "unprognostic (1.84e-3)" "potential prognostic unfavorable (5.75e-6)" "unprognostic (2.08e-3)" "unprognostic (2.52e-2)" WNT7B ENSG00000188064 "Wnt family member 7B" P56706 22 45920366-45977162 "Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.5;esophagus: 11.7;skin 1: 16.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 34.6;Conjunctival goblet cells: 48.5;Esophageal apical cells: 26.3;Esophageal basal cells: 30.5;Ocular epithelial cells: 61.2;Papillary tip epithelial cells: 39.6;Prostatic club cells: 52.2;Prostatic hillock cells: 53.9;Respiratory basal cells: 35.6;Respiratory ciliated cells: 25.6;Respiratory deuterosomal cells: 38.4;Respiratory secretory cells: 37.3;Salivary duct cells: 31.9;Transitional alveolar cells: 26.2;Urothelial cells: 65.9" "Cell type enhanced" "Detected in some" "Bergmann glia: 14.9;deep-layer near-projecting: 10.5;oligodendrocyte precursor cell: 24.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Prostate - Urothelial cells, Skin - Keratinocyte (other), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 2: Non-specific - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" "unprognostic (2.20e-3)" "potential prognostic unfavorable (3.55e-4)" "unprognostic (4.27e-1)" "unprognostic (3.66e-1)" "unprognostic (2.39e-1)" "unprognostic (9.41e-2)" "unprognostic (2.92e-2)" "unprognostic (1.64e-1)" "unprognostic (3.44e-1)" "unprognostic (1.42e-1)" "unprognostic (7.16e-2)" "unprognostic (1.59e-2)" "unprognostic (3.00e-2)" "unprognostic (3.63e-2)" "unprognostic (1.24e-2)" "unprognostic (2.94e-1)" "unprognostic (6.45e-3)" "unprognostic (2.70e-3)" "unprognostic (5.22e-2)" "unprognostic (1.26e-1)" "unprognostic (2.32e-1)" "unprognostic (3.25e-2)" "unprognostic (1.21e-1)" "unprognostic (5.22e-2)" WNT8A WNT8D ENSG00000061492 "Wnt family member 8A" Q9H1J5 5 138083990-138092365 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 2.6;Brain inhibitory neurons: 3.4;Early primary spermatocytes: 1.3;Ependymal cells: 3.0;Other brain neurons: 1.3;Retinal amacrine cells: 2.1" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "testis cancer: 1.0" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA038539 Uncertain "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 32: Cerebral cortex - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 35: Neurons - Synaptic function & neurogenesis" "HPA038539: " WNT8B ENSG00000075290 "Wnt family member 8B" Q93098 10 100463009-100483744 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "parathyroid gland: 1.1" "Cell type enhanced" "Detected in some" "Adipocytes: 4.4;Cardiomyocytes: 2.2;Early spermatids: 3.6;Epicardial cells: 4.5;Medullary thymic epithelial cells: 2.4;Respiratory deuterosomal cells: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lymphoma: 2.4;prostate cancer: 1.8" "Adrenal gland - Adrenal medulla cells, Kidney - Podocytes, Prostate - Prostate basal glandular cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA036570 Uncertain "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 15: Non-specific - Transcription" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 89: Adipocytes - Lipid metabolism" "HPA036570: " WNT9A WNT14 ENSG00000143816 "Wnt family member 9A" O14904 1 227918656-227947932 "Plasma proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 17.6;skeletal muscle: 25.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 67.2;Choroid plexus epithelial cells: 82.0;Epididymal basal cells: 52.1;Esophageal basal cells: 50.9;Esophageal suprabasal cells: 50.2;Ocular epithelial cells: 176.3;Prostatic hillock cells: 56.4;Respiratory basal cells: 53.9;Salivary basal cells: 55.7" "Group enriched" "Detected in many" 4 "choroid plexus epithelial cell: 56.4;ependymal cell: 34.5;fibroblast: 35.5" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "choroid plexus: 17.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 1, Pituitary gland - Gonadotropes, Prostate - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 1 "potential prognostic favorable (1.67e-4)" "unprognostic (1.24e-2)" "unprognostic (5.83e-2)" "unprognostic (1.04e-1)" "unprognostic (9.28e-3)" "unprognostic (1.31e-1)" "unprognostic (3.12e-1)" "unprognostic (4.30e-2)" "unprognostic (2.00e-1)" "unprognostic (1.21e-1)" "unprognostic (1.33e-1)" "unprognostic (1.56e-1)" "unprognostic (5.00e-2)" "unprognostic (1.51e-1)" "potential prognostic unfavorable (1.80e-4)" "unprognostic (6.07e-2)" "unprognostic (2.25e-1)" "unprognostic (1.01e-1)" "unprognostic (4.30e-2)" "unprognostic (1.66e-1)" "unprognostic (5.25e-2)" "unprognostic (2.69e-1)" "unprognostic (2.83e-2)" "unprognostic (5.15e-2)" WNT9B "WNT14B, WNT15" ENSG00000158955 "Wnt family member 9B" O14905 17 46833201-46886730 "Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "parathyroid gland: 13.2;seminal vesicle: 9.2" "Cell type enriched" "Detected in some" 4 "Renal collecting duct principal cells: 64.0" "Group enriched" "Detected in many" 4 "astrocyte: 6.6;Bergmann glia: 12.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "testis cancer: 6.8" "Region enriched" "Detected in single" 7 "thalamus: 5.8" "Low region specificity" "Detected in all" "HPA058361, HPA059572" Approved Approved Vesicles "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 69: Parathyroid gland - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 1 Vesicles "HPA058361: , HPA059572: " WRAP53 "FLJ10385, TCAB1, WDR79" ENSG00000141499 "WD repeat containing antisense to TP53" Q9BUR4 17 7686071-7703502 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction" "Chaperone, RNA-binding" "Disease variant, Dyskeratosis congenita" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 29.9;Fallopian tube ciliated cells: 53.8;Gastric progenitor cells: 26.9;Respiratory ciliated cells: 62.2" "Cell type enhanced" "Detected in all" "ependymal cell: 27.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 34.2" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023026, HPA028130, HPA029928" Enhanced Enhanced "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 46: Brainstem - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 107: Ciliated cells - Cilia assembly & function" 52 "Nuclear bodies" "Nucleoplasm, Cytosol" "HPA023026: , HPA028130: , HPA029928: " "potential prognostic unfavorable (6.49e-4)" "unprognostic (1.37e-1)" "unprognostic (3.40e-1)" "unprognostic (4.88e-2)" "unprognostic (1.24e-2)" "unprognostic (2.92e-2)" "unprognostic (7.36e-2)" "unprognostic (3.54e-2)" "unprognostic (1.71e-1)" "potential prognostic unfavorable (4.43e-4)" "potential prognostic favorable (9.41e-4)" "unprognostic (2.31e-1)" "unprognostic (1.18e-3)" "potential prognostic unfavorable (4.09e-5)" "unprognostic (2.26e-2)" "unprognostic (2.84e-2)" "unprognostic (1.77e-2)" "unprognostic (2.15e-1)" "unprognostic (1.48e-1)" "unprognostic (2.04e-1)" "unprognostic (3.67e-1)" "unprognostic (3.54e-3)" "unprognostic (3.19e-2)" "unprognostic (9.53e-2)" "unprognostic (1.67e-2)" "unprognostic (2.49e-2)" "unprognostic (1.25e-1)" "unprognostic (6.40e-2)" "unprognostic (3.53e-1)" "unprognostic (1.01e-2)" "unprognostic (1.71e-2)" WRAP73 WDR8 ENSG00000116213 "WD repeat containing, antisense to TP73" Q9P2S5 1 3630767-3652761 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 45.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026893 Uncertain Approved "Mid piece,Principal piece" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 64: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 37: Non-specific - mRNA processing" "Cluster 97: Non-specific - Cellular respiration" 28 "Mid piece, Principal piece" "HPA026893: " "unprognostic (4.34e-2)" "unprognostic (1.44e-1)" "unprognostic (4.34e-2)" "unprognostic (4.08e-2)" "unprognostic (2.02e-1)" "unprognostic (1.85e-1)" "potential prognostic favorable (1.82e-5)" "unprognostic (2.33e-2)" "unprognostic (2.64e-2)" "unprognostic (7.30e-2)" "unprognostic (2.04e-1)" "unprognostic (1.68e-1)" "potential prognostic unfavorable (3.48e-6)" "unprognostic (1.44e-3)" "unprognostic (1.42e-2)" "unprognostic (2.38e-1)" "unprognostic (1.83e-1)" "unprognostic (4.69e-2)" "unprognostic (2.36e-1)" "unprognostic (7.92e-2)" "unprognostic (2.94e-2)" "unprognostic (4.17e-2)" "unprognostic (3.20e-2)" "unprognostic (2.90e-1)" "unprognostic (1.41e-3)" "unprognostic (1.44e-1)" "unprognostic (3.07e-2)" "unprognostic (3.58e-2)" "unprognostic (1.89e-1)" "unprognostic (1.99e-1)" WRN "RECQ3, RECQL2" ENSG00000165392 "WRN RecQ like helicase" Q14191 8 31033788-31176138 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Exonuclease, Helicase, Hydrolase, Isomerase, Multifunctional enzyme, Nuclease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythrocyte progenitors: 366.5;Lactotrophs: 462.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009423, HPA028661" Approved Enhanced "Nuclear speckles" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 54: Non-specific - Ribosome" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Unknown function" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 59 "Nuclear speckles" "HPA009423: , HPA028661: " "unprognostic (1.71e-1)" "unprognostic (6.14e-2)" "unprognostic (2.13e-2)" "unprognostic (1.11e-1)" "unprognostic (2.42e-2)" "unprognostic (1.51e-3)" "unprognostic (2.43e-1)" "unprognostic (3.19e-2)" "unprognostic (8.43e-2)" "unprognostic (7.26e-3)" "unprognostic (5.76e-3)" "unprognostic (4.68e-3)" "unprognostic (1.14e-1)" "unprognostic (1.70e-1)" "unprognostic (2.86e-1)" "unprognostic (2.19e-1)" "unprognostic (7.25e-2)" "unprognostic (5.04e-3)" "unprognostic (2.27e-1)" "unprognostic (2.55e-2)" "unprognostic (2.43e-1)" "unprognostic (1.66e-2)" "unprognostic (3.48e-1)" "unprognostic (1.13e-2)" "unprognostic (1.25e-1)" "unprognostic (9.96e-2)" "potential prognostic favorable (2.46e-4)" "unprognostic (2.74e-1)" "unprognostic (3.86e-3)" "unprognostic (6.59e-2)" WRNIP1 "bA420G6.2, CFAP93, FAP93, FLJ22526, WHIP" ENSG00000124535 "WRN helicase interacting protein 1" Q96S55 6 2765393-2786952 "Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, Immunity, Innate immunity" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Platelets: 190.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031752, HPA031753" Enhanced Approved Nucleoplasm No No "Cluster 3: Non-specific - Nuclear processes" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 28 Nucleoplasm "HPA031752: , HPA031753: " "unprognostic (3.85e-2)" "unprognostic (4.02e-2)" "unprognostic (2.07e-2)" "unprognostic (3.76e-1)" "unprognostic (1.56e-1)" "unprognostic (1.37e-2)" "unprognostic (2.00e-1)" "unprognostic (2.42e-2)" "unprognostic (4.70e-2)" "unprognostic (7.30e-3)" "unprognostic (2.63e-3)" "unprognostic (4.73e-3)" "unprognostic (3.94e-2)" "validated prognostic unfavorable (6.40e-4)" "validated prognostic unfavorable (3.85e-4)" "unprognostic (2.75e-1)" "unprognostic (8.58e-2)" "unprognostic (1.33e-2)" "unprognostic (8.56e-2)" "unprognostic (3.39e-2)" "unprognostic (8.45e-2)" "unprognostic (2.79e-1)" "unprognostic (1.27e-1)" "unprognostic (1.90e-1)" "unprognostic (7.85e-2)" "unprognostic (2.49e-1)" "unprognostic (5.66e-2)" "unprognostic (6.43e-2)" "unprognostic (2.89e-1)" "unprognostic (8.83e-2)" "unprognostic (3.87e-2)" WSB1 "DKFZp564A122, DKFZp564B0482, SWIP1" ENSG00000109046 "WD repeat and SOCS box containing 1" Q9Y6I7 17 27294076-27315926 "Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003293 Approved Approved Mitochondria NA Yes "Cluster 40: Monocytes - Innate immune response" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 11: White matter - Signal transduction" "Cluster 56: Non-specific - Sensory perception" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 16 Mitochondria "HPA003293: " "unprognostic (4.35e-1)" "unprognostic (1.26e-1)" "unprognostic (1.96e-1)" "unprognostic (3.49e-2)" "unprognostic (9.96e-2)" "unprognostic (2.18e-2)" "unprognostic (3.52e-1)" "unprognostic (2.19e-2)" "unprognostic (4.44e-3)" "unprognostic (2.62e-1)" "unprognostic (3.69e-2)" "unprognostic (2.21e-2)" "unprognostic (1.87e-1)" "unprognostic (1.39e-2)" "unprognostic (2.08e-1)" "unprognostic (2.76e-3)" "unprognostic (4.30e-2)" "unprognostic (1.74e-1)" "potential prognostic favorable (8.33e-4)" "unprognostic (3.29e-2)" "unprognostic (2.59e-1)" "unprognostic (3.31e-1)" "potential prognostic unfavorable (2.47e-4)" "unprognostic (8.29e-2)" "potential prognostic favorable (8.05e-4)" "unprognostic (4.69e-3)" "unprognostic (2.22e-1)" "unprognostic (3.69e-2)" "unprognostic (2.71e-1)" "unprognostic (2.69e-3)" "unprognostic (1.44e-1)" WSB2 "MGC10210, SBA2" ENSG00000176871 "WD repeat and SOCS box containing 2" Q9NYS7 12 118032687-118062430 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 152.7" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 142.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Fibroblasts_1, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052606, HPA077139" Approved NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 38: Non-specific - Transcription" "Cluster 69: Urothelial cells - Basic cellular functions" 12 "HPA052606: , HPA077139: " "unprognostic (1.19e-2)" "unprognostic (2.56e-3)" "unprognostic (2.07e-3)" "unprognostic (3.43e-2)" "unprognostic (2.85e-2)" "unprognostic (5.28e-2)" "unprognostic (3.68e-2)" "unprognostic (1.06e-1)" "unprognostic (1.56e-1)" "unprognostic (2.25e-2)" "potential prognostic favorable (1.27e-4)" "unprognostic (6.65e-2)" "unprognostic (6.11e-2)" "potential prognostic unfavorable (4.73e-7)" "unprognostic (3.06e-2)" "unprognostic (4.80e-3)" "unprognostic (8.24e-2)" "unprognostic (1.57e-2)" "unprognostic (3.92e-2)" "unprognostic (2.63e-1)" "unprognostic (4.74e-3)" "unprognostic (1.40e-1)" "unprognostic (1.13e-3)" "unprognostic (1.96e-1)" "unprognostic (1.47e-1)" "unprognostic (3.02e-2)" "unprognostic (1.26e-2)" "unprognostic (3.25e-1)" "unprognostic (4.88e-2)" "unprognostic (1.44e-1)" "unprognostic (4.29e-1)" WSCD1 KIAA0523 ENSG00000179314 "WSC domain containing 1" Q658N2 17 6057807-6124427 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.6;lymphoid tissue: 12.2" "Cell type enhanced" "Detected in many" "Bergmann glia: 61.8;Early spermatids: 161.5;Lactotrophs: 51.6;Late spermatids: 172.2;Oligodendrocyte progenitor cells: 168.2;Retinal bipolar cells: 49.8" "Cell type enhanced" "Detected in all" "oligodendrocyte precursor cell: 206.2" "Cancer enriched" "Detected in many" 4 "Glioblastoma Multiforme (TCGA): 47.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 24.7" "Minor Salivary Gland - Endothelial cells, Pituitary gland - Lactotropes, Prostate - Endothelial cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015919 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" Nucleoplasm "Golgi apparatus" "HPA015919: " "unprognostic (7.94e-2)" "unprognostic (9.49e-2)" "unprognostic (2.88e-1)" "unprognostic (2.28e-1)" "unprognostic (1.75e-1)" "unprognostic (7.09e-2)" "unprognostic (1.13e-3)" "unprognostic (4.88e-2)" "potential prognostic favorable (6.93e-5)" "unprognostic (5.68e-2)" "potential prognostic favorable (1.75e-4)" "unprognostic (9.70e-3)" "unprognostic (3.00e-1)" "unprognostic (9.01e-3)" "unprognostic (1.98e-2)" "unprognostic (2.08e-1)" "unprognostic (1.78e-2)" "unprognostic (1.99e-2)" WSCD2 KIAA0789 ENSG00000075035 "WSC domain containing 2" Q2TBF2 12 108129288-108250537 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 7 "brain: 105.4" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 92.3;Brain inhibitory neurons: 65.2;Other brain neurons: 29.2;Pituitary stem cells: 48.6;Retinal amacrine cells: 96.2;Retinal bipolar cells: 104.5;Retinal horizontal cells: 54.1" "Cell type enhanced" "Detected in many" "upper rhombic lip: 200.0" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 6.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Pancreas - Beta cells, Prostate - Smooth muscle cells, Skeletal muscle - Fibroblasts, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013346, HPA048133" Approved Uncertain Nucleoplasm NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 15: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 2: Cerebellar granular cells - Neuronal signaling" Nucleoplasm "HPA013346: , HPA048133: " "unprognostic (1.54e-1)" "unprognostic (3.51e-2)" "unprognostic (7.32e-2)" "unprognostic (1.28e-1)" "unprognostic (1.46e-2)" "unprognostic (1.48e-2)" "unprognostic (1.51e-1)" "unprognostic (4.74e-3)" "unprognostic (2.06e-2)" "unprognostic (6.70e-3)" "unprognostic (3.05e-3)" WT1 "AWT1, GUD, NPHS4, WAGR, WIT-2, WT-1" ENSG00000184937 "WT1 transcription factor" P19544 11 32387775-32435564 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, RNA-binding" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 41.8;fallopian tube: 49.2;ovary: 27.9;smooth muscle: 30.9" "Cell type enhanced" "Detected in some" "Decidual stromal cells: 144.9;Endometrial stromal cells: 173.9;Epicardial cells: 163.7;Granulosa cells: 315.5;Mesothelial cells: 319.5;Ovarian stromal cells: 82.9;Podocytes: 814.3;Sertoli cells: 349.8" "Cell type enhanced" "Detected in some" "astrocyte: 1.2;Bergmann glia: 1.4;ependymal cell: 1.5" "Cancer enriched" "Detected in some" 22 "Ovary Serous Cystadenocarcinoma (TCGA): 98.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Leukemia: 10.4;ovarian cancer: 9.0" "Adipose visceral - Mesothelial cells, Kidney - Podocytes, Testis - Sertoli cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000327, HPA035717, HPA053848" Enhanced Enhanced Nucleoplasm,Cytosol NA NA "Cluster 75: Ovary - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 57: Podocytes - Glomerular filtration" 16 Nucleoplasm Cytosol "CAB000327: , HPA035717: , HPA053848: " "potential prognostic unfavorable (5.96e-4)" "unprognostic (1.27e-1)" "unprognostic (5.86e-2)" "unprognostic (4.88e-2)" "unprognostic (1.14e-1)" "unprognostic (1.68e-1)" "unprognostic (6.73e-2)" "unprognostic (1.20e-1)" "unprognostic (1.66e-1)" WTAP "KIAA0105, MGC3925, Mum2" ENSG00000146457 "WT1 associated protein" Q15007 6 159725585-159756319 "Essential proteins, Predicted intracellular proteins" "Cell cycle, mRNA processing, mRNA splicing" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 815.0;Neutrophil progenitors: 640.9;Neutrophils: 1408.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010550 Supported Enhanced "Nuclear speckles" NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 39 "Nuclear speckles" "HPA010550: " "unprognostic (3.82e-1)" "unprognostic (3.30e-2)" "unprognostic (2.58e-2)" "unprognostic (1.72e-3)" "unprognostic (2.13e-2)" "unprognostic (1.17e-1)" "unprognostic (2.30e-1)" "unprognostic (1.76e-1)" "unprognostic (6.82e-2)" "unprognostic (1.82e-1)" "unprognostic (5.81e-3)" "unprognostic (2.79e-1)" "unprognostic (9.17e-2)" "potential prognostic unfavorable (1.23e-6)" "unprognostic (3.20e-2)" "unprognostic (7.32e-2)" "unprognostic (5.46e-2)" "unprognostic (3.61e-2)" "unprognostic (4.54e-1)" "potential prognostic unfavorable (3.45e-5)" "unprognostic (5.07e-2)" "unprognostic (1.60e-1)" "potential prognostic unfavorable (1.23e-4)" "unprognostic (1.42e-1)" "unprognostic (9.40e-2)" "unprognostic (2.37e-2)" "unprognostic (2.57e-1)" "unprognostic (1.40e-1)" "unprognostic (2.52e-1)" "unprognostic (1.23e-1)" "unprognostic (2.94e-1)" WTIP ENSG00000142279 "WT1 interacting protein" A6NIX2 19 34481758-34512304 "Predicted intracellular proteins" "Cilium biogenesis/degradation, RNA-mediated gene silencing, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 92.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 128.9;Early spermatids: 65.6;Late spermatids: 78.5;Pericytes: 52.3;Transitional alveolar cells: 61.4;Vascular smooth muscle cells: 232.3" "Group enriched" "Detected in many" 9 "pericyte: 92.2;vascular associated smooth muscle cell: 284.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 15: Kidney cancer - Membrane components" "Cluster 62: Smooth muscle cells - Muscle contraction" 4 "unprognostic (8.97e-3)" "unprognostic (2.85e-2)" "unprognostic (2.17e-2)" "unprognostic (1.26e-2)" "unprognostic (1.88e-2)" "unprognostic (6.86e-2)" "unprognostic (1.18e-1)" "unprognostic (5.01e-2)" "unprognostic (2.04e-1)" "unprognostic (1.94e-1)" "potential prognostic favorable (2.07e-4)" "unprognostic (3.13e-2)" "unprognostic (1.13e-1)" "unprognostic (3.10e-1)" "unprognostic (4.14e-2)" "unprognostic (3.80e-1)" "unprognostic (2.88e-1)" "unprognostic (5.64e-3)" "unprognostic (2.89e-1)" "unprognostic (1.60e-1)" "unprognostic (6.96e-2)" "unprognostic (1.07e-1)" "unprognostic (7.83e-3)" "unprognostic (1.43e-1)" "unprognostic (5.19e-2)" "unprognostic (1.07e-2)" "unprognostic (1.57e-2)" "unprognostic (5.28e-2)" "unprognostic (1.35e-1)" "unprognostic (1.09e-1)" "unprognostic (2.83e-1)" WWC1 "KIAA0869, KIBRA, PPP1R168" ENSG00000113645 "WW and C2 domain containing 1" Q8IX03 5 168291645-168472303 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 134.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 646.0;Cone photoreceptor cells: 1037.1;Endometrial ciliated cells: 901.2;Endometrial glandular cells: 2359.1;Endometrial luminal cells: 949.9;Salivary acinar cells: 883.0" "Cell type enhanced" "Detected in all" "astrocyte: 393.8;ependymal cell: 475.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038016, HPA038017" Approved Approved "Golgi apparatus" NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 44: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 51: Secretory epithelial cells - Mixed function" 39 "Golgi apparatus" "HPA038016: , HPA038017: " "unprognostic (4.39e-1)" "unprognostic (3.43e-1)" "unprognostic (1.43e-1)" "unprognostic (4.07e-2)" "unprognostic (1.69e-1)" "unprognostic (2.29e-1)" "unprognostic (2.32e-1)" "unprognostic (3.09e-2)" "unprognostic (7.02e-3)" "unprognostic (2.24e-1)" "potential prognostic favorable (4.04e-5)" "unprognostic (6.86e-2)" "potential prognostic favorable (5.86e-5)" "unprognostic (1.82e-1)" "unprognostic (2.25e-1)" "unprognostic (2.37e-1)" "unprognostic (1.46e-1)" "unprognostic (3.41e-2)" "unprognostic (4.99e-1)" "unprognostic (6.55e-2)" "unprognostic (5.46e-2)" "unprognostic (3.72e-2)" "unprognostic (2.98e-2)" "unprognostic (2.07e-1)" "unprognostic (3.14e-1)" "unprognostic (8.72e-2)" "unprognostic (1.52e-1)" "unprognostic (1.68e-2)" "unprognostic (2.48e-1)" "unprognostic (1.52e-1)" "unprognostic (5.93e-2)" WWC2 "BOMB, FLJ22029" ENSG00000151718 "WW and C2 domain containing 2" Q6AWC2 4 183099257-183320777 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 638.7;Loop of henle epithelial cells: 359.5;Mesothelial cells: 338.4;Rod photoreceptor cells: 384.8" "Cell type enhanced" "Detected in all" "endothelial cell: 527.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Lung - Alveolar cells type 1, Skin - Endothelial cells, Spleen - Endothelial cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044005 Uncertain Approved Microtubules NA NA "Cluster 42: Retina - Visual perception" "Cluster 8: Immune cells - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 27 Microtubules "HPA044005: " "unprognostic (1.32e-1)" "unprognostic (1.91e-1)" "unprognostic (2.88e-2)" "unprognostic (1.60e-2)" "unprognostic (1.06e-1)" "unprognostic (2.01e-2)" "unprognostic (9.07e-2)" "unprognostic (2.27e-1)" "unprognostic (4.75e-3)" "unprognostic (2.24e-2)" "validated prognostic favorable (2.11e-9)" "validated prognostic favorable (6.87e-5)" "unprognostic (1.25e-1)" "unprognostic (1.29e-1)" "unprognostic (2.71e-3)" "unprognostic (1.53e-1)" "unprognostic (5.65e-2)" "unprognostic (7.50e-2)" "unprognostic (5.22e-1)" "unprognostic (5.16e-2)" "unprognostic (7.11e-3)" "unprognostic (2.25e-2)" "potential prognostic unfavorable (9.52e-4)" "unprognostic (5.97e-2)" "unprognostic (1.49e-1)" "unprognostic (2.91e-2)" "unprognostic (1.34e-1)" "unprognostic (1.89e-2)" "unprognostic (4.87e-2)" "unprognostic (2.10e-1)" "unprognostic (1.10e-2)" WWC3 "BM042, KIAA1280" ENSG00000047644 "WWC family member 3" Q9ULE0 X 10015254-10144474 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 159.6;Alveolar cells type 2: 215.7;Neutrophils: 224.9;Platelets: 169.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells" "Low region specificity" "Detected in all" HPA039814 Uncertain Approved "Actin filaments,Cytosol" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 35: Non-specific - Mixed function" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 5 Cytosol "Actin filaments" "HPA039814: " "unprognostic (4.40e-2)" "unprognostic (5.13e-2)" "unprognostic (1.53e-1)" "unprognostic (1.44e-1)" "unprognostic (1.01e-2)" "unprognostic (3.64e-2)" "unprognostic (1.73e-1)" "unprognostic (1.40e-1)" "unprognostic (2.48e-1)" "unprognostic (1.30e-3)" "potential prognostic favorable (8.82e-4)" "unprognostic (3.76e-1)" "unprognostic (3.27e-1)" "unprognostic (9.49e-3)" "unprognostic (5.04e-3)" "unprognostic (3.41e-2)" "unprognostic (4.34e-1)" "unprognostic (3.19e-1)" "unprognostic (3.66e-2)" "unprognostic (7.08e-2)" "unprognostic (7.81e-2)" "unprognostic (1.68e-1)" "unprognostic (1.92e-1)" "unprognostic (2.26e-1)" "unprognostic (1.29e-1)" "unprognostic (7.22e-3)" "unprognostic (9.23e-3)" "unprognostic (1.88e-1)" "unprognostic (1.15e-1)" "unprognostic (1.31e-1)" "unprognostic (3.03e-2)" WWOX "FOR, SDR41C1, WOX1" ENSG00000186153 "WW domain containing oxidoreductase" Q9NZC7 16 78099400-79212667 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Wnt signaling pathway" Oxidoreductase "Disease variant, Epilepsy, Neurodegeneration, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Choroid plexus epithelial cells: 2148.1;Ependymal cells: 3104.6;Podocytes: 2770.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050992 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 55: Non-specific - Transcription" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 28: Astrocytes - Homeostasis & neuron support" 78 "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA050992: " "unprognostic (2.73e-2)" "potential prognostic unfavorable (2.07e-4)" "unprognostic (1.06e-1)" "unprognostic (6.65e-3)" "unprognostic (1.05e-1)" "unprognostic (1.88e-2)" "unprognostic (9.90e-2)" "unprognostic (6.13e-3)" "unprognostic (7.55e-2)" "unprognostic (2.62e-1)" "potential prognostic favorable (8.86e-6)" "unprognostic (2.80e-1)" "potential prognostic favorable (1.71e-5)" "unprognostic (7.36e-2)" "unprognostic (2.72e-1)" "unprognostic (1.32e-1)" "unprognostic (2.59e-2)" "unprognostic (2.68e-1)" "unprognostic (1.10e-2)" "unprognostic (5.22e-2)" "unprognostic (7.83e-2)" "unprognostic (8.15e-2)" "unprognostic (2.43e-1)" "unprognostic (1.29e-1)" "unprognostic (1.27e-1)" "unprognostic (7.14e-2)" "unprognostic (7.57e-2)" "unprognostic (2.65e-1)" "unprognostic (1.17e-1)" "unprognostic (1.49e-2)" "unprognostic (3.97e-2)" WWP1 "AIP5, DKFZP434D2111" ENSG00000123124 "WW domain containing E3 ubiquitin protein ligase 1" Q9H0M0 8 86342547-86478420 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 160.5" "Cell type enhanced" "Detected in many" "Kupffer cells: 477.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023180 Approved Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 40: Non-specific - Unknown function" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 64 Cytosol "Golgi apparatus, Plasma membrane" "HPA023180: " "unprognostic (9.17e-2)" "unprognostic (1.47e-1)" "unprognostic (2.24e-2)" "unprognostic (1.11e-2)" "unprognostic (6.03e-2)" "unprognostic (1.55e-1)" "unprognostic (4.51e-2)" "unprognostic (1.37e-1)" "unprognostic (1.80e-1)" "unprognostic (2.62e-2)" "validated prognostic favorable (1.71e-6)" "validated prognostic favorable (5.51e-4)" "unprognostic (2.48e-2)" "unprognostic (1.00e-1)" "unprognostic (6.58e-2)" "unprognostic (9.99e-2)" "unprognostic (3.68e-1)" "unprognostic (1.07e-1)" "unprognostic (3.46e-1)" "potential prognostic unfavorable (3.08e-5)" "unprognostic (4.54e-3)" "potential prognostic unfavorable (1.86e-4)" "unprognostic (2.50e-2)" "unprognostic (9.01e-2)" "unprognostic (6.04e-2)" "unprognostic (1.48e-1)" "unprognostic (1.13e-1)" "unprognostic (2.44e-1)" "unprognostic (3.34e-1)" "unprognostic (8.42e-3)" "unprognostic (2.62e-1)" WWP2 AIP2 ENSG00000198373 "WW domain containing E3 ubiquitin protein ligase 2" O00308 16 69762328-69941741 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 111.7" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 339.9;Neutrophils: 748.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 18: Non-specific - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 24: Neutrophils - Innate immunity signal integration" 212 "unprognostic (2.18e-1)" "unprognostic (9.15e-2)" "unprognostic (1.33e-1)" "unprognostic (2.64e-1)" "unprognostic (2.63e-1)" "unprognostic (4.64e-2)" "unprognostic (3.34e-1)" "unprognostic (3.41e-3)" "unprognostic (3.61e-2)" "unprognostic (1.69e-3)" "potential prognostic favorable (1.41e-5)" "unprognostic (3.42e-2)" "potential prognostic favorable (2.63e-4)" "potential prognostic unfavorable (2.65e-4)" "unprognostic (6.92e-3)" "potential prognostic favorable (9.22e-4)" "unprognostic (1.25e-1)" "unprognostic (2.11e-3)" "unprognostic (1.85e-1)" "unprognostic (1.02e-1)" "unprognostic (6.42e-2)" "unprognostic (8.49e-2)" "unprognostic (2.56e-1)" "unprognostic (1.75e-1)" "unprognostic (1.60e-1)" "unprognostic (3.32e-1)" "unprognostic (2.88e-1)" "unprognostic (2.00e-1)" "unprognostic (2.23e-1)" "unprognostic (7.77e-2)" "unprognostic (1.58e-1)" WWTR1 "DKFZp586I1419, TAZ" ENSG00000018408 "WW domain containing transcription regulator 1" Q9GZV5 3 149517235-149736714 "Cancer-related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 564.7;Lymphatic endothelial cells: 576.6;Transitional alveolar cells: 546.4;Vascular endothelial cells: 781.1" "Cell type enhanced" "Detected in all" "endothelial cell: 964.7;ependymal cell: 501.0;fibroblast: 464.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Lung - Endothelial cells, Pituitary gland - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007415, CAB017483, CAB068248" Enhanced Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 55 "Nucleoplasm, Nuclear bodies" Cytosol "CAB017483: , CAB068248: , HPA007415: " "unprognostic (7.21e-2)" "unprognostic (9.36e-2)" "unprognostic (1.45e-1)" "unprognostic (2.80e-2)" "unprognostic (3.61e-2)" "unprognostic (2.55e-2)" "unprognostic (2.99e-2)" "potential prognostic unfavorable (9.35e-7)" "unprognostic (2.04e-1)" "unprognostic (3.02e-3)" "potential prognostic favorable (2.87e-7)" "unprognostic (3.03e-3)" "unprognostic (7.62e-2)" "unprognostic (2.54e-2)" "unprognostic (3.34e-2)" "unprognostic (9.88e-2)" "unprognostic (2.39e-3)" "unprognostic (1.35e-1)" "unprognostic (2.41e-1)" "unprognostic (2.15e-2)" "unprognostic (2.54e-2)" "unprognostic (3.27e-2)" "unprognostic (6.95e-2)" "unprognostic (2.73e-1)" "unprognostic (1.66e-1)" "unprognostic (1.95e-2)" "unprognostic (8.63e-3)" "unprognostic (3.59e-2)" "unprognostic (1.95e-1)" "unprognostic (2.69e-2)" "unprognostic (5.71e-2)" XAB2 "HCNP, HCRN, NTC90, SYF1" ENSG00000076924 "XPA binding protein 2" Q9HCS7 19 7619525-7629545 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, mRNA processing, mRNA splicing, Transcription" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 117.7;Breast lactating cells: 186.4;Epididymal principal cells: 174.9;Gastric chief cells: 148.5;Oocytes: 128.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048751 Supported Nucleoplasm,Vesicles NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 54: Non-specific - Ribosome" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 4: Breast lactating luminal cells - Lactation" 94 Nucleoplasm Vesicles "HPA048751: " "unprognostic (1.21e-1)" "unprognostic (2.16e-1)" "unprognostic (3.69e-2)" "potential prognostic favorable (1.32e-4)" "unprognostic (4.00e-2)" "unprognostic (7.02e-2)" "unprognostic (1.03e-1)" "unprognostic (9.93e-2)" "unprognostic (7.74e-3)" "unprognostic (8.64e-2)" "potential prognostic favorable (1.29e-4)" "unprognostic (1.99e-2)" "unprognostic (1.27e-1)" "unprognostic (1.41e-3)" "unprognostic (1.01e-1)" "unprognostic (1.22e-1)" "unprognostic (9.27e-2)" "unprognostic (3.08e-2)" "unprognostic (2.44e-2)" "unprognostic (4.68e-2)" "unprognostic (2.30e-1)" "unprognostic (7.13e-3)" "unprognostic (1.74e-1)" "unprognostic (1.29e-1)" "unprognostic (2.27e-2)" "potential prognostic favorable (5.11e-4)" "unprognostic (3.18e-1)" "unprognostic (1.49e-1)" "unprognostic (4.59e-2)" "unprognostic (1.19e-1)" "unprognostic (3.39e-1)" XAF1 "BIRC4BP, HSXIAPAF1, XIAPAF1" ENSG00000132530 "XIAP associated factor 1" Q6GPH4 17 6755447-6775647 "Predicted intracellular proteins" Apoptosis "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 75.5;Leydig cells: 87.4;Microglia: 125.0;Ovarian stromal cells: 128.2;Vascular endothelial cells: 153.5" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 177.3;endothelial cell: 566.3;pericyte: 207.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057302 Approved Supported Nucleoplasm,Mitochondria Yes NA "Cluster 28: Neutrophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 104: Brain endothelial cells - Blood brain barrier" 30 "Nucleoplasm, Mitochondria" "HPA057302: " "unprognostic (2.25e-2)" "unprognostic (1.31e-1)" "unprognostic (1.52e-1)" "unprognostic (1.15e-1)" "unprognostic (2.61e-2)" "unprognostic (7.96e-2)" "unprognostic (2.03e-1)" "unprognostic (6.02e-2)" "unprognostic (2.31e-2)" "unprognostic (3.97e-1)" "potential prognostic unfavorable (6.02e-4)" "unprognostic (1.90e-1)" "unprognostic (3.09e-1)" "unprognostic (1.92e-2)" "potential prognostic favorable (3.20e-4)" "unprognostic (6.57e-2)" "unprognostic (3.33e-2)" "unprognostic (6.17e-2)" "unprognostic (1.19e-1)" "unprognostic (6.79e-2)" "unprognostic (1.29e-1)" "unprognostic (5.20e-3)" "potential prognostic unfavorable (1.39e-4)" "unprognostic (1.51e-1)" "unprognostic (1.48e-1)" "unprognostic (4.54e-3)" "unprognostic (2.12e-1)" "unprognostic (4.29e-1)" "unprognostic (1.62e-2)" "unprognostic (2.62e-1)" "unprognostic (1.13e-1)" XAGE1A "CT12.1a, GAGED2, XAGE-1, XAGE1" ENSG00000204379 "X antigen family member 1A" Q9HD64 X 52495808-52500812 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 375 "testis: 44.0" "Cell type enhanced" "Detected in single" "Undifferentiated spermatogonia: 2.2" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "Lung Adenocarcinoma (TCGA): 563.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 258.3" HPA046363 Approved Nucleoplasm NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 6 Nucleoplasm "HPA046363: " "unprognostic (4.56e-1)" "unprognostic (3.37e-2)" "unprognostic (3.25e-1)" "unprognostic (1.77e-1)" "potential prognostic unfavorable (5.97e-10)" "unprognostic (2.10e-3)" "unprognostic (1.12e-1)" "unprognostic (6.67e-2)" "unprognostic (4.13e-1)" "unprognostic (1.90e-1)" "unprognostic (5.47e-1)" "unprognostic (4.62e-1)" "unprognostic (2.19e-2)" "unprognostic (5.42e-1)" "unprognostic (2.60e-1)" XAGE1B "CT12.1b, CT12.1c, CT12.1d, XAGE1C, XAGE1D, XAGE1E" ENSG00000204382 "X antigen family member 1B" Q9HD64 X 52512077-52520803 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 40 "testis: 61.7" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 2.0;Early primary spermatocytes: 1.7;Undifferentiated spermatogonia: 1.4" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "Lung Adenocarcinoma (TCGA): 31.0" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 17 "plasmacytoid DC: 1.6" "Lineage enriched" "Detected in single" 17 "dendritic cells: 1.6" "Low cancer specificity" "Detected in many" HPA046363 Approved Nucleoplasm NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 6 Nucleoplasm "HPA046363: " "unprognostic (1.12e-1)" "unprognostic (1.38e-1)" "potential prognostic unfavorable (8.70e-4)" "unprognostic (7.48e-2)" "unprognostic (3.61e-2)" "unprognostic (3.79e-2)" "unprognostic (5.77e-3)" "unprognostic (9.51e-3)" "unprognostic (2.82e-1)" XAGE2 "CT12.2, GAGED3, XAGE-2, XAGE2B" ENSG00000155622 "X antigen family member 2" Q96GT9 X 52369021-52375680 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 35 "placenta: 187.2" "Group enriched" "Detected in some" 45 "Cytotrophoblasts: 1044.2;Extravillous trophoblasts: 2665.3;Migrating cytotrophoblasts: 1889.9;Syncytiotrophoblasts: 1648.8" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 8.0;Lung Adenocarcinoma (TCGA): 8.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "ovarian cancer: 12.4;testis cancer: 25.7" "HPA052507, HPA060900" Supported Approved "Vesicles,Plasma membrane" NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 14 Vesicles "Plasma membrane" "HPA052507: , HPA060900: " "unprognostic (9.33e-3)" "unprognostic (1.54e-1)" "unprognostic (6.22e-2)" "unprognostic (2.14e-1)" "unprognostic (4.04e-3)" "unprognostic (2.29e-1)" "unprognostic (9.27e-2)" "unprognostic (9.99e-2)" "unprognostic (9.99e-2)" "unprognostic (5.79e-2)" "unprognostic (1.60e-3)" XAGE3 "CT12.3a, CT12.3b, GAGED4, PLAC6, pp9012, XAGE-3" ENSG00000171402 "X antigen family member 3" Q8WTP9 X 52862525-52868083 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 121 "placenta: 358.1" "Group enriched" "Detected in some" 76 "Cytotrophoblasts: 2352.9;Extravillous trophoblasts: 1499.5;Migrating cytotrophoblasts: 3156.6;Syncytiotrophoblasts: 3075.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Bladder cancer: 2.5;Brain cancer: 6.0;colorectal cancer: 3.0" "HPA052507, HPA060900" Supported Approved "Vesicles,Plasma membrane" NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 13 Vesicles "Plasma membrane" "HPA052507: , HPA060900: " "unprognostic (2.22e-2)" "unprognostic (3.40e-1)" "unprognostic (4.08e-2)" XAGE5 "CT12.5, GAGED5, XAGE-5" ENSG00000171405 "X antigen family member 5" Q8WWM1 X 52811287-52818301 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 12 "testis: 1.1" "Group enriched" "Detected in some" 6 "Differentiating spermatogonia: 15.5;Early primary spermatocytes: 9.8;Undifferentiated spermatogonia: 9.2" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Liver Hepatocellular Carcinoma (TCGA): 2.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Bone cancer: 2.5" "HPA052507, HPA055941" Uncertain Approved Nucleoplasm,Vesicles No No "Cluster 57: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 106: Spermatogonia - Spermatogonial differentiation" "Nucleoplasm, Vesicles" "HPA052507: , HPA055941: " "potential prognostic unfavorable (5.18e-4)" "unprognostic (1.20e-1)" XBP1 XBP2 ENSG00000100219 "X-box binding protein 1" P17861 22 28794555-28800597 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Angiogenesis, Apoptosis, Autophagy, Differentiation, Lipid biosynthesis, Lipid metabolism, Myogenesis, Protein transport, Stress response, Transcription, Transcription regulation, Transport, Unfolded protein response" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 1102.3;salivary gland: 792.7" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 3629.7;Breast lactating cells: 926.4;Pancreatic acinar cells: 1038.0;Plasma cells: 2196.4;Respiratory secretory cells: 959.1" "Cell type enhanced" "Detected in all" "leukocyte: 66.6" "Cancer enhanced" "Detected in all" "Breast Invasive Carcinoma (TCGA): 1746.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "breast cancer: 667.4;Myeloma: 628.2" "Breast - Breast glandular cells, Breast - Breast glandular cells, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Hepatocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Spleen - Plasma cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 8: Pancreas - Proteolysis" "Cluster 21: Non-specific - Metabolism" "Cluster 27: Breast cancer - Unknown function" "Cluster 44: Plasma cells - Antibody production & secretion" 7 "unprognostic (3.97e-2)" "unprognostic (3.26e-1)" "unprognostic (1.04e-2)" "unprognostic (3.63e-1)" "potential prognostic favorable (5.27e-4)" "unprognostic (4.16e-2)" "unprognostic (3.38e-2)" "unprognostic (3.84e-2)" "unprognostic (2.62e-2)" "unprognostic (3.83e-2)" "unprognostic (4.22e-3)" "unprognostic (2.38e-1)" "unprognostic (8.58e-3)" "unprognostic (3.29e-1)" "unprognostic (2.79e-1)" "unprognostic (7.64e-3)" "unprognostic (4.65e-2)" "unprognostic (1.99e-1)" "unprognostic (8.67e-2)" "unprognostic (2.66e-3)" "unprognostic (3.18e-1)" "unprognostic (5.99e-2)" "unprognostic (5.03e-2)" "unprognostic (5.78e-1)" "unprognostic (1.14e-1)" "unprognostic (1.62e-1)" "unprognostic (2.96e-1)" "unprognostic (2.10e-1)" "unprognostic (1.14e-2)" "unprognostic (4.93e-2)" "unprognostic (3.74e-3)" XCL1 "ATAC, LPTN, LTN, SCM-1, SCM-1a, SCYC1" ENSG00000143184 "X-C motif chemokine ligand 1" P47992 1 168576605-168582069 "Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 4.3" "Group enriched" "Detected in some" 11 "Innate lymphoid cells: 314.2;NK-cells: 232.2;T-cells: 155.1" "Cell type enriched" "Detected in single" 31 "leukocyte: 29.0" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "hypothalamus: 1.2" "Immune cell enriched" "Detected in many" 14 "NK-cell: 88.6" "Lineage enriched" "Detected in many" 14 "NK-cells: 88.6" "Cancer enhanced" "Detected in many" "testis cancer: 5.6" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Liver - NK-cells (Liver), Minor Salivary Gland - T-cells, Prostate - T-cells, Spleen - T-cells, Thyroid gland - T-cells" HPA057725 Approved "Secreted to blood" Chemokine NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 24: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 3 "HPA057725: " "unprognostic (3.83e-2)" "unprognostic (2.57e-1)" "unprognostic (5.36e-2)" "unprognostic (1.61e-1)" "potential prognostic unfavorable (3.42e-4)" "unprognostic (1.53e-1)" "unprognostic (6.86e-2)" "unprognostic (9.81e-2)" "unprognostic (1.72e-2)" "unprognostic (1.02e-1)" "unprognostic (2.34e-2)" "unprognostic (1.20e-1)" "unprognostic (1.36e-1)" "unprognostic (2.65e-1)" "unprognostic (2.53e-1)" "unprognostic (3.53e-1)" "unprognostic (4.46e-2)" XCL2 "SCM-1b, SCYC2" ENSG00000143185 "X-C motif chemokine ligand 2" Q9UBD3 1 168540768-168543997 "Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 13.3;lymphoid tissue: 13.2" "Group enriched" "Detected in some" 8 "Innate lymphoid cells: 208.3;NK-cells: 321.9;T-cells: 141.8" "Cell type enriched" "Detected in single" 347 "leukocyte: 34.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 8 "NK-cell: 424.2" "Lineage enriched" "Detected in many" 8 "NK-cells: 424.2" "Cancer enriched" "Detected in some" 7 "Sarcoma: 7.3" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Prostate - T-cells, Spleen - T-cells, Thyroid gland - T-cells" HPA057725 Approved "Secreted to blood" Chemokine NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 54: Non-specific - Transcription" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 5 "HPA057725: " "unprognostic (9.47e-2)" "unprognostic (1.03e-2)" "unprognostic (1.23e-1)" "unprognostic (1.53e-3)" "unprognostic (1.86e-2)" "unprognostic (2.44e-3)" "unprognostic (1.26e-2)" "unprognostic (8.34e-2)" "unprognostic (1.25e-3)" "unprognostic (2.25e-1)" "unprognostic (2.25e-3)" "unprognostic (5.83e-3)" "unprognostic (2.20e-1)" "unprognostic (4.21e-3)" "unprognostic (1.07e-1)" "unprognostic (1.92e-1)" "unprognostic (3.02e-2)" "unprognostic (2.48e-1)" "unprognostic (1.22e-1)" "unprognostic (1.18e-1)" "unprognostic (3.08e-3)" "unprognostic (8.28e-2)" "unprognostic (5.24e-1)" "unprognostic (1.76e-2)" "unprognostic (5.25e-2)" XCR1 "CCXCR1, GPR5" ENSG00000173578 "X-C motif chemokine receptor 1" P46094 3 46016990-46085825 "G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 8.2;placenta: 2.7" "Cell type enriched" "Detected in some" 7 "Myonuclei: 237.0" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 24 "myeloid DC: 2.3" "Lineage enriched" "Detected in single" 24 "dendritic cells: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA013169 Uncertain NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 55: Myocytes - Oxidative muscle function" 1 "HPA013169: " "unprognostic (6.28e-3)" "unprognostic (9.03e-3)" "unprognostic (1.51e-3)" "unprognostic (1.60e-2)" "unprognostic (1.61e-2)" "unprognostic (1.71e-1)" "unprognostic (8.42e-2)" "unprognostic (2.06e-2)" "unprognostic (3.44e-3)" "unprognostic (2.05e-2)" "unprognostic (2.36e-3)" XDH "XO, XOR" ENSG00000158125 "Xanthine dehydrogenase" P47989 2 31334321-31414742 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "breast: 39.2;intestine: 46.6;liver: 64.0" "Cell type enriched" "Detected in many" 16 "Breast lactating cells: 7985.9" "Cell type enhanced" "Detected in some" "cerebellar inhibitory: 10.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 13.0" "Colon - Colon enterocytes, Liver - Hepatocytes, Pituitary gland - Corticotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA062641, HPA069323" Supported Uncertain Nucleoplasm,Nucleoli "Intracellular and membrane" Enzyme No No 800000 "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 4: Breast lactating luminal cells - Lactation" 3 Nucleoplasm Nucleoli "HPA062641: , HPA069323: " "unprognostic (3.87e-1)" "unprognostic (4.92e-2)" "unprognostic (1.60e-1)" "unprognostic (3.12e-2)" "unprognostic (6.42e-3)" "unprognostic (3.77e-3)" "unprognostic (2.49e-2)" "unprognostic (9.47e-2)" "unprognostic (2.78e-3)" "potential prognostic favorable (8.04e-4)" "unprognostic (4.76e-2)" "unprognostic (2.08e-2)" "unprognostic (2.86e-2)" "unprognostic (1.79e-3)" "unprognostic (4.89e-2)" "unprognostic (1.39e-1)" "unprognostic (3.76e-3)" "unprognostic (2.56e-1)" "unprognostic (1.95e-2)" "unprognostic (2.37e-3)" "unprognostic (7.79e-3)" "unprognostic (9.32e-2)" "unprognostic (1.99e-1)" "unprognostic (1.10e-1)" XG PBDX ENSG00000124343 "Xg glycoprotein (Xg blood group)" P55808 X 2752040-2816500 "Blood group antigen proteins, Predicted membrane proteins" "Blood group antigen" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 33.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 42.8;Esophageal apical cells: 253.3;Esophageal suprabasal cells: 61.1;Fibro-adipogenic progenitors: 83.0;Fibroblasts: 37.1;Ocular epithelial cells: 29.7;Suprabasal keratinocytes: 97.5;Thymocytes: 160.1" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 17.2" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Bone cancer: 31.7" "Low region specificity" "Detected in all" NA NA "Cluster 58: Skin - Keratinization" "Cluster 22: Non-specific - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 108: Fibroblasts - ECM organization" "unprognostic (2.73e-1)" "unprognostic (4.92e-3)" "unprognostic (2.41e-1)" "unprognostic (1.16e-2)" "unprognostic (1.60e-1)" "unprognostic (1.50e-1)" "unprognostic (6.25e-2)" "unprognostic (1.55e-1)" "unprognostic (1.84e-2)" "unprognostic (1.42e-1)" "unprognostic (2.00e-1)" "unprognostic (2.12e-1)" "unprognostic (6.86e-2)" "unprognostic (1.06e-2)" "unprognostic (2.06e-3)" "unprognostic (4.01e-2)" "unprognostic (3.11e-2)" XIAP "API3, BIRC4, hILP, ILP-1" ENSG00000101966 "X-linked inhibitor of apoptosis" P98170 X 123859712-123913972 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway, Wnt signaling pathway" "Protease inhibitor, Thiol protease inhibitor, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009203, HPA042428, HPA047020" Approved Supported "Nucleoplasm,Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 42: Retina - Visual perception" "Cluster 21: Non-specific - Metabolism" "Cluster 36: Non-specific - mRNA processing" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 163 "Nucleoplasm, Cytosol" "Nucleoli, Plasma membrane" "CAB009203: , HPA042428: , HPA047020: " "unprognostic (1.22e-2)" "unprognostic (1.08e-3)" "unprognostic (3.90e-1)" "unprognostic (2.24e-2)" "unprognostic (1.69e-1)" "unprognostic (1.28e-1)" "unprognostic (1.39e-1)" "unprognostic (3.69e-1)" "unprognostic (1.37e-1)" "unprognostic (8.84e-3)" "potential prognostic favorable (3.93e-5)" "unprognostic (3.06e-2)" "unprognostic (3.44e-1)" "unprognostic (4.87e-2)" "unprognostic (3.53e-1)" "unprognostic (2.74e-1)" "unprognostic (2.86e-2)" "unprognostic (6.20e-2)" "unprognostic (1.06e-1)" "unprognostic (1.76e-1)" "unprognostic (3.63e-2)" "unprognostic (6.41e-2)" "unprognostic (5.67e-2)" "unprognostic (1.14e-1)" "unprognostic (1.07e-1)" "unprognostic (2.81e-1)" "unprognostic (5.03e-2)" "unprognostic (8.21e-2)" "unprognostic (3.10e-1)" "unprognostic (2.40e-2)" "unprognostic (5.67e-2)" XIRP1 "CMYA1, DKFZp451D042, Xin" ENSG00000168334 "Xin actin binding repeat containing 1" Q702N8 3 39183210-39192596 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "heart muscle: 602.7;skeletal muscle: 376.1" "Group enriched" "Detected in some" 5 "Cardiomyocytes: 62.0;Thymic myoid cells: 106.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Head and Neck Squamous Cell Carcinoma (TCGA): 4.1" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA016750, HPA018458, CAB026391" Enhanced Approved "Nucleoplasm,Actin filaments" NA NA "Cluster 41: Striated muscle - Muscle contraction" "Cluster 25: Non-specific - Transcription" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 8 "Actin filaments" Nucleoplasm "CAB026391: , HPA016750: , HPA018458: " "unprognostic (1.55e-1)" "unprognostic (4.35e-2)" "unprognostic (1.57e-2)" "unprognostic (2.78e-2)" "unprognostic (2.66e-1)" XIRP2 CMYA3 ENSG00000163092 "Xin actin binding repeat containing 2" A4UGR9 2 166888480-167259753 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 180.7;skeletal muscle: 962.9;tongue: 458.6" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 196.5;Myonuclei: 923.7;Thymic myoid cells: 405.2" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in some" 5 "Head and Neck Squamous Cell Carcinoma (TCGA): 9.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA034813, HPA074599" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 6 "Plasma membrane" Nucleoplasm "HPA034813: , HPA074599: " "unprognostic (3.57e-3)" "unprognostic (1.99e-1)" XK "Kx, NA, NAC, X1k, XKR1" ENSG00000047597 "X-linked Kx blood group antigen, Kell and VPS13A binding protein" P51811 X 37685791-37732130 "Blood group antigen proteins, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Blood group antigen" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 13.4;intestine: 11.4;stomach 1: 10.9" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 64.7;Foveolar cells: 47.7;Megakaryocyte progenitors: 36.8;Megakaryocytes: 43.3;Platelets: 247.0" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Rectum Adenocarcinoma (TCGA): 8.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 53 "basophil: 10.2;eosinophil: 5.8" "Lineage enriched" "Detected in single" 103 "granulocytes: 10.2" "Cancer enhanced" "Detected in many" "Myeloma: 12.3" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Prostate - Smooth muscle cells, Spleen - Erythrocytes, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019036 Approved Approved Nucleoplasm,Vesicles,Mitochondria No No "Cluster 22: Eosinophils - Transcription" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 1: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 47: Platelets - Hemostasis" Mitochondria "Nucleoplasm, Vesicles" "HPA019036: " "unprognostic (7.94e-3)" "unprognostic (1.06e-1)" "unprognostic (3.11e-1)" "unprognostic (1.97e-3)" "unprognostic (2.13e-1)" "unprognostic (1.19e-3)" "unprognostic (3.59e-1)" "unprognostic (2.15e-3)" "potential prognostic unfavorable (2.05e-4)" "unprognostic (1.72e-1)" "unprognostic (9.08e-3)" "unprognostic (5.40e-3)" "unprognostic (4.66e-2)" "unprognostic (5.34e-2)" "unprognostic (1.74e-1)" "unprognostic (1.25e-2)" "unprognostic (5.43e-3)" "unprognostic (1.23e-1)" "unprognostic (2.21e-1)" "unprognostic (2.11e-1)" "unprognostic (9.85e-2)" "unprognostic (6.72e-2)" XKR3 "MGC57211, XTES" ENSG00000172967 "XK related 3" Q5GH77 22 16783412-16825411 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 77 "testis: 7.6" "Group enriched" "Detected in some" 9 "Early spermatids: 117.2;Late primary spermatocytes: 168.9" "Cell type enhanced" "Detected in single" "fibroblast: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "neutrophil: 1.9" "Lineage enriched" "Detected in single" 13 "granulocytes: 1.9" "Group enriched" "Detected in some" 7 "Bladder cancer: 2.0;Myeloma: 7.0" "Testis - Early spermatids, Testis - Late spermatids" "HPA003379, HPA035081" Uncertain NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" "HPA003379: , HPA035081: " XKR4 KIAA1889 ENSG00000206579 "XK related 4" Q5GH76 8 55102028-55542054 "Predicted membrane proteins, Transporters" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.7;intestine: 1.7" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 412.7;Brain inhibitory neurons: 763.3;Cone photoreceptor cells: 426.4;Gonadotrophs: 615.8;Lactotrophs: 776.3;Oligodendrocyte progenitor cells: 1032.6;Other brain neurons: 587.0;Podocytes: 402.1;Respiratory ionocytes: 297.2;Retinal amacrine cells: 623.7;Schwann cells: 798.6;Thyrotrophs: 394.6" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in single" "Kidney Renal Papillary Cell Carcinoma (TCGA): 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 4.8" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Pituitary gland - Lactotropes, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025072, HPA028083" Uncertain Approved "Nucleoli,Golgi apparatus,Vesicles" NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" Vesicles "Nucleoli, Golgi apparatus" "HPA025072: , HPA028083: " "unprognostic (3.20e-3)" "unprognostic (4.66e-2)" XKR5 ENSG00000275591 "XK related 5" Q6UX68 8 6808517-6835524 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Neutrophil progenitors: 2.2;Neutrophils: 3.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 3.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 37: Neutrophil progenitors - Granulopoiesis" XKR6 "C8orf21, C8orf5, C8orf7" ENSG00000171044 "XK related 6" Q5GH73 8 10896045-11201833 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 542.9;Brain inhibitory neurons: 518.3;Distal convoluted tubule cells: 481.6;Microglia: 188.6;Oligodendrocyte progenitor cells: 384.5;Other brain neurons: 481.8;Papillary tip epithelial cells: 227.2;Podocytes: 409.1;Renal collecting duct intercalated cells: 202.0;Renal collecting duct principal cells: 199.4;Renal connecting tubule cells: 315.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 4.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA024828, HPA064769" Approved "Actin filaments" NA NA "Cluster 21: Testis - Mixed function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 102: Non-specific - Mixed function" "Actin filaments" "HPA024828: , HPA064769: " "unprognostic (1.84e-2)" "unprognostic (1.11e-1)" "unprognostic (2.01e-3)" "unprognostic (1.34e-1)" "unprognostic (2.37e-3)" "potential prognostic favorable (2.93e-4)" "unprognostic (5.59e-3)" "unprognostic (1.02e-1)" XKR7 "C20orf159, dJ310O13.4" ENSG00000260903 "XK related 7" Q5GH72 20 31968151-32003387 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 19 "brain: 14.5;pituitary gland: 4.1;retina: 4.4" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 10.6;Brain excitatory neurons: 16.0;Brain inhibitory neurons: 7.4;Cone photoreceptor cells: 14.5;Corticotrophs: 8.7;Gastric progenitor cells: 7.7;Gonadotrophs: 10.6;Lactotrophs: 18.4;Other brain neurons: 7.8;Pancreatic islet cells: 10.0;Retinal amacrine cells: 10.5;Retinal bipolar cells: 19.8;Retinal horizontal cells: 10.0;Rod photoreceptor cells: 13.6;Somatotrophs: 6.8;Thyrotrophs: 18.8" "Cell type enhanced" "Detected in many" "upper rhombic lip: 32.0" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebellum: 20.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 4.7;Neuroblastoma: 10.2" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 12.2" HPA040854 Uncertain NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 2: Cerebellar granular cells - Neuronal signaling" "HPA040854: " "unprognostic (6.21e-3)" XKR8 FLJ10307 ENSG00000158156 "XK related 8" Q9H6D3 1 27959588-27968093 "Predicted membrane proteins, Transporters" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 22.5;Cytotrophoblasts: 71.0;Migrating cytotrophoblasts: 35.6;Neutrophils: 34.5;Syncytiotrophoblasts: 19.2" "Cell type enhanced" "Detected in many" "Bergmann glia: 18.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "eosinophil: 203.2;neutrophil: 102.0" "Lineage enriched" "Detected in all" 13 "granulocytes: 203.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049984, HPA053529" Uncertain Approved "Golgi apparatus" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 44: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 63: Cytotrophoblasts - Basic cellular functions" "Golgi apparatus" "HPA049984: , HPA053529: " "unprognostic (8.41e-2)" "unprognostic (1.57e-1)" "unprognostic (5.24e-2)" "unprognostic (1.89e-3)" "unprognostic (3.72e-1)" "unprognostic (4.45e-1)" "unprognostic (1.81e-3)" "potential prognostic unfavorable (2.66e-6)" "unprognostic (2.33e-1)" "unprognostic (2.75e-3)" "unprognostic (1.51e-1)" "unprognostic (6.65e-2)" "unprognostic (3.50e-2)" "potential prognostic unfavorable (4.30e-6)" "unprognostic (6.37e-2)" "unprognostic (3.71e-2)" "unprognostic (3.20e-2)" "unprognostic (4.38e-2)" "unprognostic (2.89e-2)" "unprognostic (6.32e-2)" "unprognostic (1.47e-1)" "unprognostic (8.03e-2)" "unprognostic (1.97e-2)" "unprognostic (3.96e-2)" "unprognostic (5.55e-2)" "unprognostic (3.26e-1)" "unprognostic (1.54e-1)" "unprognostic (4.61e-1)" "unprognostic (6.39e-2)" "unprognostic (3.32e-2)" "unprognostic (1.62e-3)" XKR9 ENSG00000221947 "XK related 9" Q5GH70 8 70669339-70790371 "Predicted membrane proteins, Transporters" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 5.0;testis: 6.9" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 8.5;Loop of henle epithelial cells: 9.8;Papillary tip epithelial cells: 13.7;Podocytes: 5.4;Proximal tubule cells: 28.0;Renal collecting duct intercalated cells: 5.3;Renal collecting duct principal cells: 4.1;Renal connecting tubule cells: 7.2;Tuft cells: 11.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Stomach - Gastric mucous cells, Testis - Spermatocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA044430 Uncertain Approved Mitochondria NA NA "Cluster 21: Testis - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 4: Non-specific - Transcription" "Cluster 88: Proximal tubular cells - Transmembrane transport" Mitochondria "HPA044430: " "unprognostic (8.86e-2)" "unprognostic (3.01e-2)" "unprognostic (5.16e-2)" "unprognostic (7.90e-2)" "unprognostic (4.15e-2)" "unprognostic (1.08e-2)" "unprognostic (1.49e-2)" "unprognostic (7.57e-3)" "unprognostic (1.47e-1)" "unprognostic (3.37e-2)" "unprognostic (1.43e-1)" "unprognostic (6.73e-2)" "unprognostic (2.38e-1)" "unprognostic (1.31e-2)" "unprognostic (1.88e-1)" "unprognostic (1.55e-2)" "unprognostic (4.79e-2)" "unprognostic (5.89e-3)" "unprognostic (3.32e-3)" "unprognostic (1.73e-1)" "unprognostic (2.26e-2)" "unprognostic (1.14e-1)" "unprognostic (3.22e-1)" "unprognostic (1.94e-1)" "unprognostic (1.81e-2)" XKRX "XKR2, XPLAC" ENSG00000182489 "XK related X-linked" Q6PP77 X 100913445-100929433 "Predicted membrane proteins, Transporters" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 3.2;skin 1: 9.3" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 21.3;Alveolar cells type 1: 10.0;Alveolar cells type 2: 8.8;Ependymal cells: 8.7;Esophageal apical cells: 12.6;Pituicytes/FSCs: 16.5;Respiratory deuterosomal cells: 17.6;Transitional alveolar cells: 13.6" "Cell type enhanced" "Detected in many" "ependymal cell: 8.0" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 8.4" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 5 "naive B-cell: 1.9;naive CD4 T-cell: 1.5;naive CD8 T-cell: 1.2" "Group enriched" "Detected in many" 18 "B-cells: 1.9;T-cells: 1.5" "Low cancer specificity" "Detected in some" "Adrenal gland - Adrenal cortex cells, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 58: Skin - Keratinization" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" "unprognostic (2.91e-2)" "unprognostic (1.31e-2)" "unprognostic (2.61e-1)" "unprognostic (5.74e-3)" "unprognostic (1.76e-1)" "unprognostic (7.57e-2)" "unprognostic (1.26e-1)" "unprognostic (2.63e-2)" "unprognostic (3.07e-1)" "unprognostic (8.74e-3)" "unprognostic (4.42e-3)" "unprognostic (6.38e-2)" "unprognostic (5.81e-3)" XNDC1N ENSG00000254469 "XRCC1 N-terminal domain containing 1, N-terminal like" Q6ZNB5 11 71865504-71928654 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 29.3;Bergmann glia: 35.8;Choroid plexus epithelial cells: 39.5;Distal convoluted tubule cells: 70.0;Ependymal cells: 34.5;Loop of henle epithelial cells: 80.7;Microglia: 27.2;Oligodendrocyte progenitor cells: 27.7;Oligodendrocytes: 49.3;Papillary tip epithelial cells: 52.0;Podocytes: 40.3;Proximal tubule cells: 72.5;Renal collecting duct intercalated cells: 79.0;Renal collecting duct principal cells: 74.7;Renal connecting tubule cells: 84.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts" "Low region specificity" "Detected in all" "HPA051121, HPA051124" Uncertain Enhanced "Nucleoli,Mitotic chromosome" Yes NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 48: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 102: Non-specific - Mixed function" Nucleoli "Mitotic chromosome" "HPA051121: , HPA051124: " "unprognostic (7.17e-2)" "unprognostic (8.39e-2)" "unprognostic (6.71e-2)" "unprognostic (4.59e-2)" "unprognostic (1.89e-1)" "unprognostic (2.74e-2)" "unprognostic (8.37e-3)" "unprognostic (2.13e-1)" "potential prognostic unfavorable (6.13e-4)" "unprognostic (1.03e-2)" "unprognostic (7.32e-2)" "unprognostic (2.16e-2)" "unprognostic (1.43e-2)" "unprognostic (2.05e-1)" "unprognostic (2.66e-3)" "unprognostic (2.57e-2)" "unprognostic (6.11e-2)" "unprognostic (7.20e-2)" "unprognostic (1.69e-2)" "unprognostic (2.52e-2)" "unprognostic (1.45e-2)" "unprognostic (3.43e-1)" "unprognostic (5.78e-2)" "unprognostic (4.33e-3)" "potential prognostic unfavorable (1.01e-4)" "unprognostic (8.61e-2)" "unprognostic (1.29e-1)" "unprognostic (1.10e-1)" "unprognostic (2.19e-1)" XPA "XP1, XPAC" ENSG00000136936 "XPA, DNA damage recognition and repair factor" P23025 9 97674909-97697340 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" DNA-binding "Cancer-related genes, Disease variant, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000155, HPA068327" Supported Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 74: Non-specific - Signal transduction" "Cluster 16: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 41 "Nuclear bodies" "Nucleoplasm, Cytosol" "CAB000155: , HPA068327: " "unprognostic (5.25e-3)" "unprognostic (5.78e-2)" "unprognostic (1.09e-1)" "unprognostic (1.08e-1)" "unprognostic (5.86e-3)" "unprognostic (3.73e-2)" "unprognostic (7.15e-2)" "unprognostic (2.31e-2)" "unprognostic (2.31e-1)" "unprognostic (1.03e-1)" "potential prognostic favorable (5.85e-8)" "unprognostic (1.17e-3)" "unprognostic (3.24e-2)" "unprognostic (8.25e-3)" "unprognostic (8.97e-3)" "unprognostic (6.06e-2)" "unprognostic (1.33e-1)" "unprognostic (3.06e-1)" "unprognostic (2.01e-2)" "unprognostic (1.22e-1)" "unprognostic (1.28e-1)" "unprognostic (1.98e-2)" "unprognostic (1.74e-1)" "unprognostic (1.99e-2)" "unprognostic (1.62e-1)" "unprognostic (1.52e-2)" "unprognostic (2.01e-1)" "unprognostic (1.44e-2)" "unprognostic (2.09e-1)" "unprognostic (5.29e-2)" "unprognostic (1.21e-1)" XPC "RAD4, XPCC" ENSG00000154767 "XPC complex subunit, DNA damage recognition and repair factor" Q01831 3 14145147-14178621 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009932, HPA035707, HPA069673" Supported Enhanced "Nucleoplasm,Plasma membrane" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 49: Non-specific - Transcription" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 60 Nucleoplasm "Plasma membrane" "CAB009932: , HPA035707: , HPA069673: " "unprognostic (1.66e-2)" "unprognostic (5.63e-2)" "unprognostic (5.04e-2)" "unprognostic (5.07e-1)" "unprognostic (1.28e-1)" "unprognostic (9.67e-2)" "unprognostic (3.68e-1)" "unprognostic (1.66e-1)" "unprognostic (2.23e-2)" "unprognostic (1.44e-2)" "validated prognostic favorable (1.12e-7)" "validated prognostic favorable (1.69e-4)" "unprognostic (4.26e-3)" "unprognostic (1.31e-1)" "unprognostic (6.60e-2)" "unprognostic (3.11e-2)" "unprognostic (4.15e-2)" "unprognostic (2.18e-1)" "unprognostic (2.89e-1)" "unprognostic (8.15e-3)" "unprognostic (6.29e-2)" "unprognostic (5.76e-2)" "unprognostic (1.23e-1)" "unprognostic (3.88e-1)" "unprognostic (3.36e-2)" "unprognostic (4.83e-3)" "unprognostic (2.47e-1)" "unprognostic (1.29e-1)" "unprognostic (1.78e-1)" "unprognostic (3.70e-2)" "unprognostic (1.01e-2)" XPNPEP1 "XPNPEP, XPNPEPL, XPNPEPL1" ENSG00000108039 "X-prolyl aminopeptidase 1" Q9NQW7 10 109864766-109923553 "Enzymes, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreatic acinar cells: 134.8;Platelets: 447.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025196, HPA030419, HPA030420, HPA030422, CAB080286, CAB080287" Supported Enhanced Cytosol NA NA 840000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 60: Stomach - Digestion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 47: Platelets - Hemostasis" 7 Cytosol "CAB025196: , CAB080286: , CAB080287: , HPA030419: , HPA030420: , HPA030422: " "unprognostic (1.60e-1)" "unprognostic (4.84e-2)" "unprognostic (2.40e-1)" "unprognostic (2.69e-1)" "unprognostic (1.04e-2)" "unprognostic (1.17e-1)" "unprognostic (3.13e-1)" "potential prognostic favorable (2.24e-4)" "unprognostic (2.37e-2)" "unprognostic (2.85e-2)" "potential prognostic favorable (1.04e-4)" "unprognostic (3.57e-3)" "unprognostic (1.69e-2)" "potential prognostic unfavorable (6.96e-5)" "unprognostic (1.16e-1)" "unprognostic (1.41e-2)" "potential prognostic unfavorable (4.47e-4)" "unprognostic (1.16e-1)" "unprognostic (8.87e-2)" "unprognostic (1.33e-1)" "unprognostic (2.52e-2)" "unprognostic (1.72e-3)" "unprognostic (1.06e-1)" "unprognostic (7.74e-2)" "unprognostic (4.79e-2)" "unprognostic (3.36e-2)" "unprognostic (4.75e-2)" "unprognostic (7.79e-2)" "unprognostic (8.35e-2)" "unprognostic (6.22e-2)" "unprognostic (9.55e-2)" XPNPEP2 ENSG00000122121 "X-prolyl aminopeptidase 2" O43895 X 129738949-129769536 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "intestine: 156.9;kidney: 145.6" "Cell type enriched" "Detected in some" 6 "Enterocytes: 497.8" "Cell type enhanced" "Detected in some" "endothelial cell: 1.0;fibroblast: 1.9" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 22.6" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "gdT-cell: 4.3;intermediate monocyte: 1.4;MAIT T-cell: 1.2;memory CD4 T-cell: 1.3;memory CD8 T-cell: 2.8;naive CD8 T-cell: 2.0;non-classical monocyte: 2.8;T-reg: 1.4" "Group enriched" "Detected in many" 7 "monocytes: 2.8;T-cells: 4.3" "Cancer enhanced" "Detected in some" "colorectal cancer: 1.2;Leukemia: 1.0" "Adipose visceral - Macrophages, Breast - Macrophages, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Fibroblasts_2, Skin - Fibroblasts_2" "Not detected" "Not detected" "Region enriched" "Detected in single" 9 "spinal cord: 2.4" "HPA000339, CAB025136, CAB025269, HPA064568" Enhanced Approved "Plasma membrane,Cytosol" "Intracellular and membrane" Enzyme NA NA 7100000 "Cluster 33: Non-specific - ATP binding" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 1: Enterocytes - Absorption and Digestion" "Plasma membrane, Cytosol" "CAB025136: , CAB025269: , HPA000339: , HPA064568: " "unprognostic (5.46e-3)" "unprognostic (6.00e-2)" "unprognostic (7.71e-2)" "unprognostic (1.05e-2)" "unprognostic (2.98e-2)" "potential prognostic favorable (4.91e-4)" "unprognostic (2.26e-3)" "unprognostic (3.85e-1)" "unprognostic (5.95e-2)" "unprognostic (1.63e-1)" "unprognostic (2.77e-1)" "unprognostic (1.64e-3)" "unprognostic (2.05e-2)" "unprognostic (2.45e-2)" XPNPEP3 "APP3, ICP55, NPHPL1" ENSG00000196236 "X-prolyl aminopeptidase 3" Q9NQH7 22 40857077-40932815 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Disease variant, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 375.5;Late spermatids: 457.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000527 Approved Supported Mitochondria,Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 55: Non-specific - Transcription" "Cluster 66: Non-specific - Mitochondria" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 11 Mitochondria Cytosol "HPA000527: " "unprognostic (3.58e-2)" "unprognostic (1.79e-2)" "unprognostic (4.62e-1)" "unprognostic (7.73e-2)" "unprognostic (8.88e-3)" "unprognostic (1.38e-2)" "unprognostic (2.37e-1)" "unprognostic (6.66e-3)" "unprognostic (7.66e-2)" "unprognostic (3.33e-2)" "unprognostic (4.16e-1)" "unprognostic (2.98e-1)" "unprognostic (1.17e-1)" "unprognostic (2.41e-1)" "unprognostic (1.85e-1)" "unprognostic (5.33e-2)" "unprognostic (2.46e-1)" "unprognostic (1.71e-1)" "unprognostic (2.01e-2)" "unprognostic (8.86e-2)" "unprognostic (2.90e-2)" "unprognostic (1.65e-1)" "unprognostic (1.98e-2)" "unprognostic (1.36e-1)" "unprognostic (2.60e-2)" "unprognostic (4.29e-2)" "unprognostic (3.04e-2)" "unprognostic (1.57e-2)" "unprognostic (2.18e-1)" "unprognostic (5.00e-2)" "unprognostic (2.32e-2)" XPO1 "CRM-1, CRM1, emb" ENSG00000082898 "Exportin 1" O14980 2 61476032-61538741 "Cancer-related genes, Essential proteins, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, mRNA transport, Protein transport, Transport" RNA-binding "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010184, HPA042933" Supported Approved "Nucleoplasm,Nuclear membrane,Vesicles,Primary cilium,Primary cilium tip,Cytosol" NA NA 310000 "Cluster 13: Non-specific - Mitochondria" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 27: Non-specific - Cell proliferation" 200 "Nucleoplasm, Nuclear membrane" "Vesicles, Primary cilium, Primary cilium tip, Cytosol" "CAB010184: , HPA042933: " "unprognostic (1.40e-1)" "unprognostic (2.69e-2)" "unprognostic (1.58e-1)" "unprognostic (2.22e-2)" "unprognostic (1.41e-1)" "unprognostic (3.88e-2)" "unprognostic (9.88e-2)" "unprognostic (7.21e-3)" "unprognostic (2.27e-1)" "unprognostic (1.77e-2)" "potential prognostic favorable (1.38e-4)" "unprognostic (2.64e-2)" "unprognostic (1.35e-1)" "unprognostic (6.24e-3)" "unprognostic (5.86e-2)" "unprognostic (1.04e-2)" "unprognostic (3.57e-3)" "unprognostic (3.36e-1)" "unprognostic (6.90e-3)" "unprognostic (8.17e-3)" "unprognostic (4.32e-1)" "validated prognostic unfavorable (4.44e-5)" "validated prognostic unfavorable (9.55e-4)" "unprognostic (9.94e-2)" "unprognostic (1.09e-3)" "unprognostic (6.72e-2)" "unprognostic (1.41e-2)" "unprognostic (1.84e-1)" "unprognostic (2.06e-1)" "unprognostic (2.09e-2)" "unprognostic (7.97e-3)" XPO4 "FLJ13046, KIAA1721" ENSG00000132953 "Exportin 4" Q9C0E2 13 20777329-20903048 "Plasma proteins, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 41.5" "Cell type enriched" "Detected in all" 8 "Myonuclei: 1953.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053768 Supported Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 19: Non-specific - Unknown function" "Cluster 55: Myocytes - Oxidative muscle function" 20 Nucleoplasm Cytosol "HPA053768: " "unprognostic (1.91e-2)" "unprognostic (1.91e-1)" "unprognostic (1.61e-1)" "potential prognostic unfavorable (5.06e-4)" "unprognostic (1.13e-1)" "unprognostic (1.35e-1)" "unprognostic (6.76e-2)" "unprognostic (4.30e-2)" "unprognostic (3.43e-1)" "unprognostic (1.35e-3)" "potential prognostic favorable (7.94e-6)" "unprognostic (2.20e-3)" "unprognostic (2.58e-2)" "unprognostic (1.09e-3)" "unprognostic (2.07e-2)" "unprognostic (9.57e-2)" "unprognostic (7.65e-2)" "unprognostic (5.51e-2)" "unprognostic (9.30e-2)" "unprognostic (1.00e-2)" "unprognostic (1.11e-1)" "unprognostic (1.56e-1)" "unprognostic (1.88e-2)" "unprognostic (2.16e-2)" "unprognostic (1.18e-1)" "unprognostic (8.82e-2)" "unprognostic (4.38e-2)" "unprognostic (7.51e-2)" "unprognostic (1.78e-1)" "unprognostic (1.49e-1)" "unprognostic (1.10e-1)" XPO5 KIAA1291 ENSG00000124571 "Exportin 5" Q9HAV4 6 43522334-43576038 "Essential proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, Protein transport, RNA-mediated gene silencing, Transport" "RNA-binding, tRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epicardial cells: 118.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012357, HPA018402, HPA023959, HPA029909" Enhanced Enhanced Nucleoplasm,Cytosol NA NA 13000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 39: Testis - Nuclear processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 28: Non-specific - Nuclear processes" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 43 Nucleoplasm Cytosol "CAB012357: , HPA018402: , HPA023959: , HPA029909: " "unprognostic (7.28e-3)" "unprognostic (4.77e-2)" "unprognostic (8.33e-2)" "unprognostic (1.46e-2)" "unprognostic (4.58e-1)" "unprognostic (9.99e-2)" "unprognostic (6.51e-2)" "unprognostic (2.26e-2)" "unprognostic (1.42e-2)" "unprognostic (1.74e-1)" "potential prognostic favorable (5.86e-4)" "unprognostic (3.87e-2)" "unprognostic (1.85e-1)" "validated prognostic unfavorable (5.40e-7)" "validated prognostic unfavorable (6.53e-5)" "unprognostic (8.27e-2)" "unprognostic (8.01e-3)" "unprognostic (1.08e-1)" "unprognostic (1.05e-2)" "unprognostic (3.35e-1)" "unprognostic (1.35e-1)" "unprognostic (1.33e-2)" "unprognostic (3.96e-2)" "unprognostic (1.16e-1)" "unprognostic (1.08e-2)" "unprognostic (9.45e-2)" "unprognostic (1.12e-2)" "unprognostic (4.29e-1)" "unprognostic (1.80e-1)" "unprognostic (4.69e-2)" "unprognostic (9.07e-2)" XPO6 "FLJ22519, KIAA0370, RANBP20" ENSG00000169180 "Exportin 6" Q96QU8 16 28097976-28211965 "Metabolic proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 10 "Neutrophils: 2960.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 6 "neutrophil: 203.4" "Lineage enriched" "Detected in all" 9 "granulocytes: 203.4" "Low cancer specificity" "Detected in all" "Lung - Neutrophils_2, Spleen - Neutrophils_2, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038246 Uncertain Supported "Nucleoplasm,Nucleoli,Plasma membrane,Cytosol" No No "Cluster 21: Neutrophils - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 27: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 24: Neutrophils - Innate immunity signal integration" 11 "Nucleoplasm, Nucleoli" "Plasma membrane, Cytosol" "HPA038246: " "unprognostic (2.25e-2)" "unprognostic (1.30e-1)" "unprognostic (1.94e-2)" "unprognostic (1.98e-2)" "unprognostic (1.53e-1)" "unprognostic (1.23e-1)" "unprognostic (4.03e-1)" "potential prognostic favorable (2.95e-5)" "unprognostic (5.07e-2)" "unprognostic (1.67e-1)" "validated prognostic unfavorable (5.67e-9)" "validated prognostic unfavorable (1.42e-4)" "unprognostic (2.22e-1)" "potential prognostic unfavorable (9.00e-5)" "unprognostic (2.38e-2)" "unprognostic (1.28e-2)" "unprognostic (4.57e-3)" "unprognostic (5.65e-2)" "unprognostic (2.51e-1)" "unprognostic (6.39e-2)" "unprognostic (2.54e-3)" "unprognostic (6.46e-2)" "potential prognostic unfavorable (1.23e-5)" "unprognostic (1.50e-1)" "unprognostic (2.29e-1)" "unprognostic (4.76e-2)" "unprognostic (5.91e-2)" "unprognostic (1.48e-1)" "unprognostic (1.62e-1)" "unprognostic (3.00e-1)" "unprognostic (1.30e-1)" XPO7 "EXP7, KIAA0745, RANBP16" ENSG00000130227 "Exportin 7" Q9UIA9 8 21919662-22006585 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043727, HPA048153" Uncertain NA NA 120000 "Cluster 25: Non-specific - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 32 "HPA043727: , HPA048153: " "unprognostic (1.28e-2)" "unprognostic (9.05e-2)" "potential prognostic favorable (3.68e-4)" "unprognostic (1.54e-1)" "potential prognostic favorable (1.29e-4)" "unprognostic (1.13e-1)" "unprognostic (1.82e-1)" "unprognostic (1.12e-3)" "unprognostic (8.82e-3)" "unprognostic (2.69e-3)" "potential prognostic favorable (6.93e-6)" "unprognostic (1.78e-2)" "unprognostic (5.18e-2)" "unprognostic (8.52e-3)" "unprognostic (3.35e-2)" "unprognostic (4.68e-1)" "unprognostic (6.17e-2)" "unprognostic (1.81e-1)" "unprognostic (2.28e-1)" "unprognostic (3.90e-1)" "unprognostic (3.99e-3)" "unprognostic (5.36e-2)" "unprognostic (4.97e-2)" "unprognostic (9.44e-2)" "unprognostic (3.26e-2)" "potential prognostic favorable (7.01e-4)" "unprognostic (4.59e-1)" "unprognostic (5.09e-1)" "unprognostic (7.31e-2)" "unprognostic (2.39e-2)" "unprognostic (2.68e-1)" XPOT XPO3 ENSG00000184575 "Exportin for tRNA" O43592 12 64404392-64451125 "Essential proteins, Predicted intracellular proteins, Transporters" Transport "RNA-binding, tRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048067, HPA057602" Enhanced Nucleoplasm,Cytosol NA NA 35000 "Cluster 1: T-cells - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 13: Non-specific - Mixed function" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 21 Nucleoplasm Cytosol "HPA048067: , HPA057602: " "unprognostic (1.29e-3)" "potential prognostic unfavorable (9.88e-4)" "unprognostic (1.74e-1)" "unprognostic (2.07e-2)" "unprognostic (9.98e-2)" "unprognostic (4.31e-2)" "unprognostic (3.28e-2)" "unprognostic (2.11e-1)" "unprognostic (1.76e-1)" "potential prognostic unfavorable (5.69e-7)" "potential prognostic unfavorable (1.40e-5)" "unprognostic (3.03e-3)" "potential prognostic unfavorable (2.02e-4)" "potential prognostic unfavorable (5.25e-8)" "unprognostic (7.78e-3)" "unprognostic (1.95e-2)" "potential prognostic unfavorable (5.12e-4)" "unprognostic (1.43e-1)" "unprognostic (3.52e-2)" "unprognostic (3.35e-2)" "unprognostic (7.00e-2)" "unprognostic (7.83e-3)" "unprognostic (1.38e-2)" "unprognostic (3.40e-2)" "unprognostic (1.87e-3)" "unprognostic (1.11e-1)" "unprognostic (2.34e-2)" "unprognostic (1.69e-1)" "unprognostic (1.89e-1)" "unprognostic (6.51e-2)" "unprognostic (1.63e-1)" XPR1 "SLC53A1, SYG1, X3" ENSG00000143324 "Xenotropic and polytropic retrovirus receptor 1" Q9UBH6 1 180632022-180890279 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 580.2;Pituicytes/FSCs: 650.6;Salivary myoepithelial cells: 817.6;Thymic myoid cells: 550.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016557 Supported NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 35: Non-specific - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 12 "HPA016557: " "unprognostic (2.45e-2)" "unprognostic (2.96e-1)" "unprognostic (2.14e-2)" "unprognostic (5.48e-3)" "unprognostic (8.37e-3)" "unprognostic (1.80e-1)" "unprognostic (2.18e-1)" "unprognostic (1.32e-1)" "unprognostic (1.31e-2)" "unprognostic (3.20e-2)" "potential prognostic favorable (7.21e-6)" "unprognostic (1.71e-2)" "unprognostic (2.07e-2)" "unprognostic (1.56e-3)" "unprognostic (2.09e-2)" "unprognostic (9.90e-2)" "unprognostic (6.76e-2)" "unprognostic (7.72e-2)" "unprognostic (1.02e-1)" "unprognostic (1.75e-1)" "unprognostic (3.56e-2)" "unprognostic (8.05e-2)" "unprognostic (3.62e-2)" "unprognostic (8.37e-2)" "unprognostic (3.15e-2)" "unprognostic (9.53e-3)" "unprognostic (3.50e-1)" "unprognostic (1.84e-1)" "unprognostic (4.09e-1)" "unprognostic (4.74e-1)" "unprognostic (3.88e-1)" XRCC1 RCC ENSG00000073050 "X-ray repair cross complementing 1" P18887 19 43543311-43580473 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "Cancer-related genes, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pituitary gland - Lactotropes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005427, HPA006717" Supported Enhanced Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 54: Non-specific - Ribosome" "Cluster 15: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 63 Nucleoplasm "CAB005427: , HPA006717: " "unprognostic (2.44e-2)" "unprognostic (1.71e-2)" "unprognostic (1.06e-1)" "unprognostic (2.64e-1)" "unprognostic (1.92e-1)" "unprognostic (2.65e-1)" "unprognostic (3.24e-1)" "unprognostic (3.75e-1)" "unprognostic (5.58e-2)" "unprognostic (2.66e-1)" "unprognostic (9.76e-3)" "unprognostic (7.12e-2)" "unprognostic (1.40e-3)" "potential prognostic unfavorable (4.58e-5)" "unprognostic (1.61e-2)" "unprognostic (6.29e-2)" "unprognostic (4.40e-3)" "potential prognostic favorable (9.87e-5)" "unprognostic (7.45e-3)" "unprognostic (1.52e-1)" "unprognostic (4.63e-1)" "unprognostic (7.67e-2)" "unprognostic (2.23e-1)" "unprognostic (5.49e-2)" "unprognostic (6.80e-2)" "unprognostic (1.61e-1)" "unprognostic (1.36e-1)" "unprognostic (1.13e-1)" "unprognostic (2.69e-3)" "unprognostic (1.23e-1)" "unprognostic (2.03e-1)" XRCC2 FANCU ENSG00000196584 "X-ray repair cross complementing 2" O43543 7 152644776-152676193 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes, Disease variant, Fanconi anemia, Premature ovarian failure" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 5.5" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 21.5;Early primary spermatocytes: 41.6;Erythrocyte progenitors: 44.1;Extravillous trophoblasts: 31.9;Late primary spermatocytes: 21.9;Megakaryocyte progenitors: 101.9;Megakaryocyte-Erythroid progenitors: 20.9;Migrating cytotrophoblasts: 23.3;Monocyte progenitors: 23.7;Syncytiotrophoblasts: 20.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Lung - Mitotic cells (Lung), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065153 Approved Nucleoplasm,Vesicles NA NA "Cluster 44: Bone marrow - Nuclear processes" "Cluster 9: Non-specific - Receptor signaling" "Cluster 39: Non-specific - Transcription" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 13 "Nucleoplasm, Vesicles" "HPA065153: " "unprognostic (1.16e-3)" "unprognostic (4.15e-2)" "unprognostic (2.73e-1)" "unprognostic (1.50e-2)" "unprognostic (2.46e-2)" "unprognostic (3.33e-1)" "unprognostic (2.29e-1)" "unprognostic (3.63e-2)" "unprognostic (4.41e-2)" "potential prognostic unfavorable (5.74e-4)" "potential prognostic unfavorable (3.44e-4)" "potential prognostic unfavorable (5.25e-4)" "unprognostic (6.94e-3)" "unprognostic (6.07e-2)" "unprognostic (8.96e-2)" "unprognostic (1.45e-2)" "unprognostic (2.97e-1)" "unprognostic (5.23e-3)" "unprognostic (2.94e-2)" "unprognostic (8.78e-3)" "unprognostic (4.32e-2)" "unprognostic (1.45e-1)" "unprognostic (1.95e-1)" "unprognostic (4.71e-2)" XRCC3 ENSG00000126215 "X-ray repair cross complementing 3" O43542 14 103697609-103715504 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 122.9;Epicardial cells: 166.0;Erythrocyte progenitors: 38.1;Megakaryocyte progenitors: 39.0" "Cell type enhanced" "Detected in many" "Bergmann glia: 15.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062422, HPA068953" Enhanced Nucleoplasm NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 58: Skin - Keratinization" "Cluster 6: Non-specific - Immune response" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 17 Nucleoplasm "HPA062422: , HPA068953: " "unprognostic (3.19e-2)" "unprognostic (6.99e-3)" "unprognostic (1.28e-1)" "unprognostic (4.42e-2)" "unprognostic (1.42e-1)" "unprognostic (4.09e-1)" "unprognostic (1.80e-1)" "unprognostic (1.26e-1)" "unprognostic (8.83e-2)" "unprognostic (1.26e-2)" "potential prognostic unfavorable (3.79e-4)" "unprognostic (5.33e-2)" "unprognostic (7.28e-2)" "potential prognostic unfavorable (6.54e-5)" "unprognostic (1.14e-2)" "unprognostic (5.41e-2)" "unprognostic (3.85e-3)" "unprognostic (1.37e-1)" "unprognostic (2.81e-2)" "unprognostic (3.47e-2)" "unprognostic (2.27e-1)" "unprognostic (1.86e-3)" "unprognostic (2.65e-2)" "unprognostic (6.31e-3)" "unprognostic (3.15e-2)" "unprognostic (2.35e-1)" "unprognostic (1.11e-3)" "unprognostic (1.71e-1)" "unprognostic (2.76e-1)" "unprognostic (2.36e-1)" "unprognostic (8.00e-3)" XRCC4 ENSG00000152422 "X-ray repair cross complementing 4" Q13426 5 83077498-83353787 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Monocyte progenitors: 204.4;Neutrophil progenitors: 211.4;Neutrophils: 289.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "HPA006801, HPA051538" Supported Enhanced Nucleoplasm NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 21: Non-specific - Metabolism" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 46 Nucleoplasm "HPA006801: , HPA051538: " "unprognostic (1.36e-2)" "potential prognostic unfavorable (2.40e-5)" "unprognostic (4.87e-2)" "unprognostic (1.91e-2)" "unprognostic (1.21e-1)" "unprognostic (7.36e-3)" "unprognostic (1.12e-1)" "unprognostic (1.99e-2)" "unprognostic (6.43e-3)" "potential prognostic unfavorable (6.14e-4)" "potential prognostic favorable (1.46e-6)" "unprognostic (4.21e-1)" "unprognostic (1.35e-1)" "potential prognostic unfavorable (3.84e-4)" "unprognostic (6.99e-2)" "unprognostic (1.43e-2)" "potential prognostic unfavorable (3.70e-5)" "unprognostic (8.15e-2)" "unprognostic (4.44e-3)" "unprognostic (3.42e-3)" "potential prognostic unfavorable (2.99e-5)" "unprognostic (1.22e-2)" "unprognostic (1.31e-1)" "unprognostic (4.39e-3)" "unprognostic (9.86e-2)" "unprognostic (2.85e-1)" "unprognostic (1.21e-1)" "unprognostic (7.18e-2)" "unprognostic (1.14e-1)" "unprognostic (1.21e-1)" "unprognostic (1.12e-1)" XRCC5 "KARP-1, KU80, Ku86, KUB2" ENSG00000079246 "X-ray repair cross complementing 5" P13010 2 216107464-216206303 "Cancer-related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Host-virus interaction, Immunity, Innate immunity, Ribosome biogenesis, Transcription, Transcription regulation" "Activator, DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004468, HPA025813, HPA064685" Supported Supported Nucleoplasm NA NA 2600000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 61: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 182 Nucleoplasm "CAB004468: , HPA025813: , HPA064685: " "unprognostic (8.50e-3)" "unprognostic (1.43e-2)" "unprognostic (5.56e-2)" "unprognostic (2.15e-1)" "unprognostic (1.29e-1)" "unprognostic (2.82e-1)" "unprognostic (1.54e-1)" "unprognostic (1.41e-2)" "unprognostic (8.18e-2)" "unprognostic (2.03e-3)" "validated prognostic favorable (2.95e-5)" "validated prognostic favorable (3.64e-4)" "unprognostic (5.51e-2)" "validated prognostic unfavorable (5.24e-5)" "validated prognostic unfavorable (2.95e-4)" "potential prognostic unfavorable (5.38e-4)" "unprognostic (1.51e-2)" "unprognostic (1.65e-1)" "unprognostic (2.42e-1)" "unprognostic (1.36e-1)" "unprognostic (1.63e-1)" "unprognostic (1.03e-2)" "unprognostic (3.04e-1)" "unprognostic (1.30e-1)" "unprognostic (8.22e-2)" "unprognostic (6.76e-3)" "unprognostic (1.93e-1)" "unprognostic (1.34e-1)" "unprognostic (2.61e-2)" "unprognostic (1.63e-1)" "unprognostic (1.26e-1)" XRCC6 "D22S671, D22S731, G22P1, KU70, ML8" ENSG00000196419 "X-ray repair cross complementing 6" P12956 22 41621163-41664048 "Cancer-related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation" "Activator, DNA-binding, Helicase, Hydrolase, Lyase, Multifunctional enzyme" "Cancer-related genes, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 478.1;Early primary spermatocytes: 532.5;Late primary spermatocytes: 494.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004254, HPA047549, HPA062226" Enhanced Enhanced Nucleoplasm No No 1600000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 39: Testis - Nuclear processes" "Cluster 21: Non-specific - Metabolism" "Cluster 66: Non-specific - Mitochondria" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 292 Nucleoplasm "CAB004254: , HPA047549: , HPA062226: " "unprognostic (1.29e-2)" "unprognostic (2.38e-2)" "unprognostic (7.72e-2)" "potential prognostic favorable (6.58e-4)" "unprognostic (2.20e-2)" "unprognostic (3.56e-1)" "unprognostic (6.04e-3)" "unprognostic (3.17e-1)" "unprognostic (9.02e-3)" "potential prognostic unfavorable (1.87e-4)" "potential prognostic favorable (8.25e-6)" "unprognostic (4.17e-3)" "unprognostic (3.53e-1)" "potential prognostic unfavorable (1.60e-4)" "unprognostic (2.93e-3)" "unprognostic (1.14e-3)" "unprognostic (1.27e-1)" "unprognostic (5.49e-2)" "unprognostic (7.33e-3)" "unprognostic (1.19e-1)" "unprognostic (3.04e-2)" "unprognostic (6.21e-2)" "unprognostic (8.16e-2)" "unprognostic (2.17e-1)" "potential prognostic favorable (7.10e-4)" "unprognostic (6.03e-2)" "unprognostic (4.54e-2)" "unprognostic (3.38e-1)" "unprognostic (3.80e-1)" "unprognostic (1.37e-1)" "unprognostic (3.00e-1)" XRN1 SEP1 ENSG00000114127 "5'-3' exoribonuclease 1" Q8IZH2 3 142306607-142448062 "Essential proteins, Predicted intracellular proteins" "DNA-binding, Exonuclease, Hydrolase, Nuclease, RNA-binding" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035005, HPA035006" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 26 "Plasma membrane, Cytosol" "HPA035005: , HPA035006: " "unprognostic (1.86e-2)" "unprognostic (2.56e-1)" "unprognostic (8.61e-2)" "unprognostic (1.44e-1)" "unprognostic (2.66e-1)" "unprognostic (3.20e-2)" "unprognostic (5.02e-2)" "unprognostic (1.49e-1)" "unprognostic (1.04e-2)" "unprognostic (1.34e-2)" "unprognostic (2.25e-3)" "unprognostic (6.41e-3)" "unprognostic (1.31e-1)" "unprognostic (2.16e-1)" "unprognostic (2.49e-3)" "unprognostic (1.97e-1)" "unprognostic (4.60e-2)" "unprognostic (4.18e-1)" "unprognostic (6.01e-2)" "unprognostic (1.40e-1)" "unprognostic (4.58e-2)" "unprognostic (1.50e-3)" "unprognostic (4.18e-3)" "unprognostic (7.97e-2)" "unprognostic (4.64e-2)" "potential prognostic favorable (2.47e-4)" "unprognostic (1.19e-1)" "unprognostic (1.67e-1)" "unprognostic (2.40e-1)" "unprognostic (2.16e-2)" "unprognostic (5.40e-3)" XRN2 ENSG00000088930 "5'-3' exoribonuclease 2" Q9H0D6 20 21303331-21389825 "Essential proteins, Predicted intracellular proteins" "mRNA processing, Transcription, Transcription regulation, Transcription termination" "DNA-binding, Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 513.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Macrophages, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047118, HPA050485" Supported Enhanced Nucleoplasm,Nucleoli NA NA 30000 "Cluster 28: Neutrophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 24: Neutrophils - Innate immunity signal integration" 53 Nucleoli Nucleoplasm "HPA047118: , HPA050485: " "unprognostic (3.81e-2)" "unprognostic (8.21e-2)" "unprognostic (6.82e-3)" "potential prognostic unfavorable (6.15e-5)" "unprognostic (7.62e-2)" "unprognostic (3.00e-1)" "unprognostic (2.09e-1)" "unprognostic (4.45e-1)" "unprognostic (3.21e-1)" "unprognostic (3.39e-3)" "potential prognostic favorable (1.29e-5)" "unprognostic (2.58e-1)" "unprognostic (3.61e-2)" "potential prognostic unfavorable (5.19e-5)" "unprognostic (2.09e-2)" "unprognostic (2.85e-2)" "unprognostic (1.69e-1)" "unprognostic (7.93e-2)" "unprognostic (7.80e-2)" "unprognostic (1.72e-1)" "unprognostic (1.92e-2)" "unprognostic (3.72e-3)" "unprognostic (3.76e-1)" "unprognostic (1.78e-1)" "unprognostic (4.78e-3)" "unprognostic (2.94e-2)" "unprognostic (1.92e-1)" "unprognostic (4.38e-1)" "unprognostic (4.42e-1)" "unprognostic (1.96e-2)" "unprognostic (1.56e-1)" XRRA1 FLJ00225 ENSG00000166435 "X-ray radiation resistance associated 1" Q6P2D8 11 74807739-74949200 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epicardial cells: 500.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA039263 Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 32: Basophils - Transcription" "Cluster 21: Testis - Mixed function" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" Nucleoplasm "Nuclear bodies" "HPA039263: " "unprognostic (3.44e-1)" "unprognostic (1.92e-1)" "unprognostic (1.26e-1)" "unprognostic (2.10e-2)" "unprognostic (7.35e-2)" "potential prognostic favorable (2.61e-4)" "unprognostic (1.66e-1)" "unprognostic (1.01e-1)" "unprognostic (8.15e-2)" "unprognostic (5.41e-3)" "unprognostic (2.59e-3)" "unprognostic (7.21e-3)" "unprognostic (1.21e-1)" "unprognostic (1.14e-1)" "unprognostic (1.11e-2)" "unprognostic (4.90e-1)" "unprognostic (5.54e-2)" "unprognostic (2.75e-2)" "unprognostic (2.81e-1)" "unprognostic (1.84e-1)" "unprognostic (2.09e-2)" "unprognostic (3.95e-2)" "unprognostic (2.47e-2)" "unprognostic (3.65e-1)" "unprognostic (2.26e-1)" "unprognostic (1.73e-2)" "unprognostic (2.83e-2)" "unprognostic (3.21e-1)" "unprognostic (5.90e-2)" "unprognostic (6.61e-2)" "unprognostic (3.36e-1)" XXYLT1 "C3orf21, FLJ35155" ENSG00000173950 "Xyloside xylosyltransferase 1" Q8NBI6 3 195068284-195271159 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 10.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 120000 "Cluster 29: Non-specific - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 24: Neurons - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 7: Non-specific - Transcription" 8 "unprognostic (8.89e-2)" "unprognostic (9.29e-3)" "unprognostic (1.94e-1)" "unprognostic (2.36e-1)" "unprognostic (2.74e-2)" "unprognostic (2.12e-1)" "unprognostic (4.50e-1)" "unprognostic (3.01e-1)" "unprognostic (2.12e-1)" "unprognostic (6.18e-2)" "unprognostic (4.97e-2)" "unprognostic (2.11e-1)" "unprognostic (8.24e-3)" "unprognostic (1.16e-3)" "unprognostic (5.55e-3)" "unprognostic (2.37e-2)" "unprognostic (1.11e-2)" "unprognostic (3.82e-1)" "unprognostic (2.30e-1)" "unprognostic (4.06e-2)" "unprognostic (2.00e-2)" "unprognostic (1.06e-1)" "unprognostic (7.25e-2)" "unprognostic (1.15e-1)" "unprognostic (3.35e-2)" "unprognostic (2.26e-1)" "unprognostic (5.21e-2)" "unprognostic (9.68e-3)" "unprognostic (1.81e-1)" XYLB "FLJ10343, FLJ12539" ENSG00000093217 Xylulokinase O75191 3 38346760-38421348 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Xylose metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 31.2" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 108.7;Hepatocytes: 142.2;Proximal tubule cells: 249.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA037863, HPA038415" Uncertain Approved "Nuclear speckles" NA NA 23000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 88: Proximal tubular cells - Transmembrane transport" "Nuclear speckles" "HPA037863: , HPA038415: " "unprognostic (8.69e-2)" "unprognostic (1.25e-1)" "unprognostic (4.60e-3)" "unprognostic (1.78e-1)" "unprognostic (9.62e-2)" "unprognostic (2.85e-1)" "unprognostic (1.67e-1)" "unprognostic (5.82e-2)" "unprognostic (2.80e-2)" "potential prognostic favorable (9.34e-6)" "unprognostic (6.02e-3)" "unprognostic (2.74e-1)" "unprognostic (5.28e-2)" "unprognostic (2.28e-1)" "unprognostic (1.29e-1)" "unprognostic (3.17e-2)" "unprognostic (5.08e-3)" "unprognostic (5.23e-2)" "unprognostic (2.82e-1)" "unprognostic (2.64e-1)" "unprognostic (7.85e-2)" "unprognostic (5.10e-1)" "unprognostic (3.16e-2)" "unprognostic (1.13e-3)" "unprognostic (2.29e-1)" "unprognostic (1.11e-2)" "unprognostic (1.65e-1)" "unprognostic (2.45e-1)" "unprognostic (2.41e-2)" XYLT1 "PXYLT1, XT-I" ENSG00000103489 "Xylosyltransferase 1" Q86Y38 16 17101769-17470960 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Glycosyltransferase, Transferase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 6 "Bergmann glia: 2103.6;Choroid plexus epithelial cells: 714.5;Oligodendrocyte progenitor cells: 1744.3" "Cell type enhanced" "Detected in all" "Bergmann glia: 1956.0;oligodendrocyte precursor cell: 1799.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.0" "Lineage enriched" "Detected in single" 4 "monocytes: 2.0" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Prostate - Smooth muscle cells, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007478, HPA007966" Approved Approved "Endoplasmic reticulum,Plasma membrane" "Secreted to blood" Enzyme NA NA 50000 "Cluster 40: Monocytes - Innate immune response" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 51: Neurons - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 1 "Plasma membrane" "Endoplasmic reticulum" "HPA007478: , HPA007966: " "unprognostic (2.03e-3)" "unprognostic (1.43e-1)" "unprognostic (1.56e-1)" "unprognostic (1.02e-1)" "unprognostic (2.41e-1)" "unprognostic (1.37e-1)" "unprognostic (2.82e-1)" "unprognostic (3.52e-2)" "unprognostic (1.43e-1)" "potential prognostic favorable (1.81e-4)" "unprognostic (1.97e-2)" "unprognostic (4.08e-1)" "unprognostic (1.37e-1)" "unprognostic (1.93e-2)" "unprognostic (1.88e-2)" "unprognostic (1.99e-1)" "unprognostic (1.10e-1)" "unprognostic (1.77e-1)" "unprognostic (1.41e-1)" "unprognostic (2.46e-1)" "unprognostic (2.80e-1)" "unprognostic (1.70e-3)" "unprognostic (2.01e-1)" "unprognostic (1.03e-1)" "unprognostic (4.85e-2)" XYLT2 "PXYLT2, XT-II" ENSG00000015532 "Xylosyltransferase 2" Q9H1B5 17 50346126-50363138 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Glycosyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "stomach 1: 85.0" "Cell type enhanced" "Detected in many" "Early spermatids: 395.3;Gastric chief cells: 159.4;Late primary spermatocytes: 104.2;Late spermatids: 121.3;Mucous neck cells: 106.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" Enzyme NA NA 950000 "Cluster 11: T-cells - Unknown function" "Cluster 60: Stomach - Digestion" "Cluster 15: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 12 "unprognostic (9.31e-2)" "unprognostic (6.30e-2)" "unprognostic (3.95e-1)" "unprognostic (1.25e-1)" "unprognostic (6.93e-2)" "unprognostic (3.10e-2)" "unprognostic (1.72e-2)" "unprognostic (2.17e-1)" "unprognostic (1.01e-1)" "unprognostic (1.62e-2)" "unprognostic (6.15e-2)" "unprognostic (5.37e-1)" "unprognostic (2.99e-1)" "potential prognostic unfavorable (6.88e-4)" "unprognostic (3.47e-2)" "unprognostic (1.28e-1)" "unprognostic (2.72e-2)" "unprognostic (8.89e-2)" "unprognostic (1.74e-1)" "unprognostic (3.69e-2)" "unprognostic (3.38e-1)" "unprognostic (1.74e-2)" "unprognostic (5.05e-2)" "unprognostic (2.21e-1)" "unprognostic (1.31e-1)" "unprognostic (5.05e-2)" "unprognostic (4.66e-2)" "unprognostic (2.07e-1)" "unprognostic (5.82e-2)" "unprognostic (3.97e-2)" "unprognostic (3.07e-1)" YAE1 "C7orf36, CIAB2, GK003, YAE1D1" ENSG00000241127 "YAE1 maturation factor of ABCE1" Q9NRH1 7 39566385-39610320 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 108.9;Oocytes: 82.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019226, HPA031249" Uncertain Approved Cytosol NA NA "Cluster 1: T-cells - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 67: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 16 Cytosol "HPA019226: , HPA031249: " "unprognostic (2.57e-2)" "unprognostic (3.70e-1)" "unprognostic (7.52e-3)" "unprognostic (2.34e-1)" "unprognostic (3.93e-1)" "unprognostic (6.42e-3)" "unprognostic (2.41e-1)" "unprognostic (1.56e-1)" "unprognostic (2.00e-2)" "potential prognostic favorable (1.28e-6)" "unprognostic (3.52e-2)" "unprognostic (1.44e-1)" "potential prognostic unfavorable (1.13e-5)" "unprognostic (2.26e-2)" "unprognostic (4.36e-1)" "unprognostic (2.38e-2)" "unprognostic (7.76e-2)" "unprognostic (9.65e-3)" "unprognostic (3.90e-1)" "unprognostic (3.05e-1)" "unprognostic (1.64e-2)" "unprognostic (5.69e-2)" "unprognostic (1.21e-3)" "unprognostic (2.61e-1)" "unprognostic (4.32e-3)" "unprognostic (2.46e-2)" "unprognostic (3.28e-2)" "unprognostic (1.58e-1)" "unprognostic (1.72e-1)" YAF2 ENSG00000015153 "YY1 associated factor 2" Q8IY57 12 42157104-42238349 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026867 Supported Supported Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 14: Neurons - Synaptic function" "Cluster 38: Non-specific - Transcription" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 71 Nucleoplasm "HPA026867: " "unprognostic (3.18e-1)" "unprognostic (6.08e-2)" "unprognostic (1.05e-2)" "unprognostic (2.38e-1)" "unprognostic (8.69e-2)" "unprognostic (1.87e-1)" "unprognostic (4.19e-1)" "unprognostic (6.12e-3)" "unprognostic (2.59e-1)" "unprognostic (1.09e-2)" "potential prognostic favorable (8.79e-4)" "unprognostic (2.32e-1)" "unprognostic (2.19e-2)" "unprognostic (6.06e-3)" "unprognostic (1.64e-1)" "unprognostic (5.29e-2)" "unprognostic (1.83e-1)" "unprognostic (2.08e-1)" "unprognostic (7.82e-2)" "unprognostic (1.74e-1)" "unprognostic (8.99e-2)" "unprognostic (2.81e-1)" "potential prognostic unfavorable (2.84e-4)" "unprognostic (1.82e-1)" "unprognostic (5.79e-2)" "unprognostic (3.10e-2)" "unprognostic (1.40e-2)" "unprognostic (2.23e-1)" "unprognostic (4.14e-1)" "unprognostic (1.34e-1)" "unprognostic (1.81e-1)" YAP1 "YAP-1, YAP65" ENSG00000137693 "Yes1 associated transcriptional regulator" P46937 11 102110447-102233424 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Repressor" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 19 "astrocyte: 275.7;Bergmann glia: 354.0;choroid plexus epithelial cell: 404.0;endothelial cell: 232.3;ependymal cell: 371.9;fibroblast: 351.3;pericyte: 191.6;vascular associated smooth muscle cell: 263.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009370, HPA038884, HPA038885, CAB069915, HPA070359, CAB080528, CAB080529, CAB080530" Enhanced Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 75: Ovary - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 51: Secretory epithelial cells - Mixed function" 377 Nucleoplasm "Nucleoli, Cytosol" "CAB009370: , CAB069915: , CAB080528: , CAB080529: , CAB080530: , HPA038884: , HPA038885: , HPA070359: " "unprognostic (1.53e-1)" "unprognostic (1.56e-1)" "unprognostic (8.38e-2)" "unprognostic (7.13e-3)" "unprognostic (3.24e-1)" "unprognostic (1.61e-1)" "unprognostic (2.89e-1)" "unprognostic (1.31e-3)" "unprognostic (3.89e-1)" "unprognostic (1.96e-3)" "potential prognostic favorable (6.42e-5)" "unprognostic (2.42e-3)" "unprognostic (3.02e-1)" "unprognostic (8.98e-2)" "unprognostic (7.42e-2)" "unprognostic (1.42e-2)" "unprognostic (8.32e-2)" "unprognostic (1.25e-1)" "unprognostic (2.35e-1)" "unprognostic (9.38e-2)" "unprognostic (5.46e-2)" "unprognostic (2.15e-3)" "unprognostic (2.62e-1)" "unprognostic (1.70e-1)" "unprognostic (5.63e-3)" "unprognostic (6.04e-2)" "unprognostic (1.30e-2)" "unprognostic (3.47e-2)" "unprognostic (1.50e-1)" "unprognostic (2.54e-1)" "unprognostic (1.19e-1)" YARS1 "tyrRS, YARS, YRS, YTS" ENSG00000134684 "Tyrosyl-tRNA synthetase 1" P54577 1 32775237-32818031 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase, RNA-binding, tRNA-binding" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017936, HPA018950, HPA018954" Enhanced Supported "Nuclear bodies,Cytosol" No No 930000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 36: Brain & Liver - Signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 13: Non-specific - Mixed function" "Cluster 17: Non-specific - RNA processing" 19 Cytosol "Nuclear bodies" "HPA017936: , HPA018950: , HPA018954: " "unprognostic (1.77e-2)" "unprognostic (8.99e-3)" "unprognostic (9.22e-2)" "unprognostic (1.05e-1)" "unprognostic (5.68e-3)" "unprognostic (4.71e-2)" "unprognostic (2.21e-1)" "unprognostic (1.35e-2)" "unprognostic (4.07e-3)" "unprognostic (2.90e-3)" "unprognostic (2.30e-2)" "unprognostic (7.23e-3)" "potential prognostic unfavorable (1.22e-9)" "unprognostic (5.31e-2)" "potential prognostic unfavorable (6.13e-4)" "unprognostic (8.80e-2)" "unprognostic (1.29e-1)" "unprognostic (1.18e-1)" "unprognostic (7.78e-3)" "unprognostic (1.18e-1)" "potential prognostic unfavorable (1.53e-4)" "unprognostic (2.57e-3)" "unprognostic (1.88e-1)" "unprognostic (2.52e-2)" "unprognostic (3.54e-1)" "unprognostic (5.10e-3)" "unprognostic (1.66e-1)" "unprognostic (2.25e-1)" "unprognostic (1.26e-1)" YARS2 "CGI-04, FLJ13995, mt-TyrRS" ENSG00000139131 "Tyrosyl-tRNA synthetase 2" Q9Y2Z4 12 32727490-32755897 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 115.7;Epicardial cells: 122.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038721, HPA057610, HPA074097" Uncertain Supported "Nuclear bodies,Mitochondria" NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 108 Mitochondria "Nuclear bodies" "HPA038721: , HPA057610: , HPA074097: " "unprognostic (6.05e-2)" "unprognostic (1.10e-1)" "unprognostic (1.48e-1)" "unprognostic (1.15e-3)" "unprognostic (4.96e-2)" "unprognostic (1.05e-2)" "unprognostic (1.91e-1)" "unprognostic (1.35e-3)" "unprognostic (2.20e-2)" "unprognostic (3.14e-2)" "unprognostic (2.57e-2)" "unprognostic (1.11e-2)" "unprognostic (7.33e-3)" "validated prognostic unfavorable (2.31e-7)" "validated prognostic unfavorable (3.87e-4)" "unprognostic (1.61e-3)" "unprognostic (3.60e-3)" "unprognostic (1.68e-1)" "unprognostic (1.56e-1)" "unprognostic (2.55e-1)" "unprognostic (2.05e-2)" "unprognostic (2.05e-3)" "unprognostic (1.20e-3)" "unprognostic (1.38e-2)" "unprognostic (1.44e-2)" "unprognostic (1.84e-1)" "unprognostic (5.36e-2)" "unprognostic (2.58e-1)" "unprognostic (1.63e-1)" "unprognostic (9.40e-2)" "unprognostic (1.07e-1)" YBEY C21orf57 ENSG00000182362 "YbeY metalloendoribonuclease" P58557 21 46286342-46297751 "Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 75.3" "Group enriched" "Detected in many" 4 "Early spermatids: 315.1;Late primary spermatocytes: 725.1;Late spermatids: 354.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016593, HPA018162" Approved Approved Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 67: Testis - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 25: Non-specific - Ribosome" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 3 Nucleoplasm "HPA016593: , HPA018162: " "unprognostic (4.36e-2)" "unprognostic (2.27e-3)" "unprognostic (1.40e-1)" "unprognostic (1.73e-1)" "unprognostic (5.32e-2)" "unprognostic (2.37e-1)" "unprognostic (2.47e-1)" "unprognostic (1.54e-1)" "unprognostic (2.89e-3)" "potential prognostic favorable (6.69e-4)" "unprognostic (1.11e-1)" "unprognostic (2.60e-2)" "unprognostic (1.45e-1)" "unprognostic (4.42e-2)" "unprognostic (2.48e-3)" "unprognostic (1.39e-1)" "unprognostic (8.38e-2)" "unprognostic (2.51e-2)" "unprognostic (1.34e-1)" "unprognostic (2.51e-3)" "unprognostic (1.34e-2)" "unprognostic (9.66e-3)" "unprognostic (3.33e-1)" "unprognostic (2.44e-1)" "unprognostic (1.34e-1)" "unprognostic (1.66e-2)" "unprognostic (9.16e-2)" "unprognostic (2.66e-2)" "unprognostic (1.07e-1)" "unprognostic (1.36e-1)" YBX1 "BP-8, CSDA2, CSDB, DBPB, MDR-NF1, NSEP-1, NSEP1, YB-1, YB1" ENSG00000065978 "Y-box binding protein 1" P67809 1 42682418-42703805 "Cancer-related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins, Transcription factors" "mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Activator, DNA-binding, Mitogen, Repressor, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 1910.6" "Cell type enhanced" "Detected in all" "Early spermatids: 7800.5;Kupffer cells: 2418.8;Late primary spermatocytes: 9300.8;Late spermatids: 3964.9;Megakaryocytes: 2528.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005875, HPA040304, HPA057159" Supported Supported "Endoplasmic reticulum,Vesicles,Plasma membrane,Cytosol" "Intracellular and membrane" Transcription NA NA 1200000 "Cluster 25: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 37: Non-specific - mRNA processing" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 222 Cytosol "Endoplasmic reticulum, Vesicles, Plasma membrane" "CAB005875: , HPA040304: , HPA057159: " "unprognostic (1.46e-2)" "unprognostic (1.72e-1)" "unprognostic (3.00e-2)" "unprognostic (5.36e-2)" "unprognostic (2.59e-3)" "unprognostic (1.44e-1)" "unprognostic (1.67e-1)" "unprognostic (1.22e-2)" "unprognostic (3.24e-2)" "unprognostic (1.17e-1)" "unprognostic (1.18e-3)" "unprognostic (2.47e-3)" "unprognostic (1.13e-2)" "validated prognostic unfavorable (1.60e-8)" "validated prognostic unfavorable (4.48e-8)" "validated prognostic unfavorable (6.44e-4)" "validated prognostic unfavorable (2.92e-4)" "unprognostic (2.09e-1)" "unprognostic (2.20e-1)" "unprognostic (2.42e-3)" "unprognostic (1.50e-1)" "unprognostic (7.18e-3)" "unprognostic (1.18e-1)" "unprognostic (1.70e-3)" "unprognostic (1.13e-1)" "unprognostic (7.05e-2)" "unprognostic (1.45e-1)" "unprognostic (9.68e-2)" "unprognostic (3.97e-1)" "unprognostic (3.20e-2)" "unprognostic (8.41e-3)" YBX2 "Contrin, CSDA3, MSY2" ENSG00000006047 "Y-box binding protein 2" Q9Y2T7 17 7288263-7294639 "Predicted intracellular proteins, Transcription factors" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 87 "testis: 493.0" "Cell type enhanced" "Detected in some" "Early primary spermatocytes: 29.7;Early spermatids: 85.1;Late primary spermatocytes: 119.9;Late spermatids: 126.3" "Cell type enhanced" "Detected in some" "hippocampal CA4: 6.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 6.3" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary gland ductal cells, Skin - Eccrine sweat gland cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "CAB012332, HPA053904, HPA056744" Enhanced NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 51: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 11 "CAB012332: , HPA053904: , HPA056744: " "unprognostic (1.03e-2)" "unprognostic (2.92e-1)" "unprognostic (8.54e-2)" "unprognostic (1.94e-1)" "unprognostic (1.20e-1)" "unprognostic (9.36e-2)" "unprognostic (9.44e-2)" "unprognostic (4.67e-2)" "unprognostic (9.26e-2)" "unprognostic (4.00e-2)" "unprognostic (8.59e-2)" "unprognostic (2.39e-1)" "unprognostic (9.29e-2)" "unprognostic (3.09e-1)" "potential prognostic unfavorable (6.81e-4)" "unprognostic (1.20e-2)" "unprognostic (5.42e-2)" "unprognostic (1.44e-1)" "unprognostic (1.26e-1)" YBX3 "CSDA, CSDA1, dbpA, ZONAB" ENSG00000060138 "Y-box binding protein 3" P16989 12 10699089-10723323 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "skeletal muscle: 4495.4;tongue: 1528.5" "Cell type enhanced" "Detected in many" "Early spermatids: 1270.6;Esophageal apical cells: 1633.3;Late primary spermatocytes: 1712.4;Pancreatic acinar cells: 1391.3;Thymic myoid cells: 4539.8" "Cell type enhanced" "Detected in many" "endothelial cell: 209.6;vascular associated smooth muscle cell: 238.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 6.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Neutrophils, Heart muscle - Macrophages, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034838 Approved Supported Cytosol NA NA 190000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 12: Non-specific - Vasculature" "Cluster 38: Non-specific - Transcription" "Cluster 103: Non-specific - Basic cellular processes" 30 Cytosol "HPA034838: " "unprognostic (1.66e-1)" "unprognostic (4.42e-2)" "unprognostic (1.10e-1)" "unprognostic (1.35e-1)" "unprognostic (1.56e-2)" "unprognostic (1.93e-1)" "unprognostic (2.40e-1)" "potential prognostic unfavorable (8.68e-4)" "unprognostic (3.19e-1)" "potential prognostic unfavorable (1.76e-4)" "unprognostic (3.90e-1)" "unprognostic (9.22e-3)" "unprognostic (3.00e-2)" "unprognostic (1.38e-3)" "potential prognostic unfavorable (8.77e-4)" "unprognostic (2.05e-1)" "unprognostic (1.26e-1)" "unprognostic (3.46e-2)" "unprognostic (2.69e-2)" "unprognostic (1.08e-3)" "potential prognostic unfavorable (8.32e-4)" "unprognostic (1.09e-1)" "unprognostic (4.12e-2)" "potential prognostic favorable (1.67e-5)" "unprognostic (1.50e-1)" "unprognostic (5.49e-2)" "unprognostic (4.42e-1)" "unprognostic (2.19e-1)" "unprognostic (7.62e-3)" YDJC ENSG00000161179 "YdjC chitooligosaccharide deacetylase homolog" A8MPS7 22 21628089-21630064 "Predicted intracellular proteins" "Carbohydrate metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 83.0;Extravillous trophoblasts: 83.5;Migrating cytotrophoblasts: 70.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001501 Approved "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 66: Non-specific - Mitochondria" "Cluster 97: Non-specific - Cellular respiration" "Golgi apparatus, Vesicles" Cytosol "HPA001501: " "unprognostic (1.50e-1)" "unprognostic (8.60e-2)" "unprognostic (7.64e-2)" "unprognostic (2.52e-1)" "unprognostic (9.77e-2)" "unprognostic (6.11e-3)" "unprognostic (4.12e-2)" "unprognostic (4.03e-3)" "unprognostic (1.16e-2)" "unprognostic (2.75e-1)" "unprognostic (3.42e-3)" "unprognostic (2.68e-2)" "unprognostic (6.09e-2)" "unprognostic (1.44e-3)" "unprognostic (3.97e-3)" "unprognostic (1.11e-2)" "unprognostic (6.81e-2)" "unprognostic (1.35e-1)" "unprognostic (4.44e-2)" "unprognostic (1.38e-3)" "unprognostic (1.74e-1)" "unprognostic (1.21e-2)" "unprognostic (2.54e-1)" "unprognostic (2.14e-1)" "unprognostic (3.70e-3)" "unprognostic (1.02e-1)" "unprognostic (1.03e-1)" "unprognostic (1.24e-1)" "unprognostic (1.47e-1)" "unprognostic (3.59e-2)" "unprognostic (1.12e-1)" YEATS2 "FLJ10201, FLJ12841, FLJ13308, KIAA1197" ENSG00000163872 "YEATS domain containing 2" Q9ULM3 3 183697797-183812624 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" Epilepsy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 261.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Liver - Vascular endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036741, HPA045891" Uncertain Approved Nucleoplasm NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 61: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 7: Non-specific - Transcription" 36 Nucleoplasm "HPA036741: , HPA045891: " "unprognostic (1.17e-1)" "unprognostic (2.62e-2)" "unprognostic (4.92e-2)" "unprognostic (4.10e-2)" "unprognostic (7.27e-2)" "unprognostic (1.67e-1)" "unprognostic (8.76e-2)" "unprognostic (1.86e-3)" "unprognostic (1.90e-2)" "unprognostic (1.14e-3)" "unprognostic (2.38e-3)" "unprognostic (6.51e-2)" "unprognostic (5.60e-2)" "potential prognostic unfavorable (5.97e-7)" "unprognostic (3.26e-2)" "unprognostic (9.53e-2)" "unprognostic (1.18e-3)" "unprognostic (3.15e-2)" "unprognostic (1.34e-2)" "unprognostic (6.11e-2)" "unprognostic (1.94e-1)" "unprognostic (3.37e-3)" "potential prognostic unfavorable (5.99e-4)" "unprognostic (1.07e-2)" "unprognostic (9.05e-3)" "unprognostic (2.30e-2)" "unprognostic (1.97e-1)" "unprognostic (2.37e-1)" "unprognostic (3.36e-1)" "unprognostic (7.09e-2)" "unprognostic (1.96e-1)" YEATS4 "GAS41, NuBI-1, YAF9" ENSG00000127337 "YEATS domain containing 4" O95619 12 69359710-69390870 "Essential proteins, Predicted intracellular proteins" "Growth regulation, Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 360.6;Late primary spermatocytes: 204.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072532 Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 38: Non-specific - Transcription" "Cluster 3: Early primary spermatocytes - Early meiosis" 72 Nucleoplasm "Nuclear membrane" "HPA072532: " "unprognostic (2.81e-1)" "unprognostic (1.28e-1)" "unprognostic (8.34e-2)" "unprognostic (3.21e-2)" "unprognostic (4.26e-2)" "unprognostic (3.47e-1)" "unprognostic (2.09e-1)" "unprognostic (2.64e-1)" "unprognostic (1.98e-1)" "unprognostic (3.02e-2)" "potential prognostic favorable (8.62e-6)" "unprognostic (1.94e-1)" "unprognostic (1.89e-2)" "validated prognostic unfavorable (7.75e-5)" "validated prognostic unfavorable (1.76e-4)" "unprognostic (2.73e-3)" "unprognostic (6.53e-2)" "unprognostic (2.38e-2)" "unprognostic (7.75e-2)" "unprognostic (6.48e-2)" "unprognostic (3.57e-1)" "unprognostic (1.98e-1)" "unprognostic (6.26e-2)" "unprognostic (8.01e-2)" "unprognostic (5.52e-3)" "unprognostic (6.72e-2)" "unprognostic (1.85e-2)" "unprognostic (2.98e-1)" "unprognostic (4.71e-1)" "unprognostic (2.25e-1)" "unprognostic (1.41e-2)" YES1 "c-yes, HsT441, Yes" ENSG00000176105 "YES proto-oncogene 1, Src family tyrosine kinase" P07947 18 721588-812546 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Lymphatic endothelial cells: 307.0;NK-cells: 528.7" "Group enriched" "Detected in many" 4 "endothelial cell: 298.3;leukocyte: 168.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 9 "basophil: 20.1" "Lineage enriched" "Detected in many" 9 "granulocytes: 20.1" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Skeletal muscle - Endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004370, HPA026480" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 44: Non-specific - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 112 "Plasma membrane, Cytosol" "CAB004370: , HPA026480: " "unprognostic (4.13e-1)" "unprognostic (1.85e-1)" "unprognostic (5.76e-2)" "unprognostic (4.79e-3)" "unprognostic (6.11e-2)" "unprognostic (2.28e-1)" "unprognostic (3.04e-2)" "unprognostic (3.79e-1)" "unprognostic (1.26e-1)" "potential prognostic unfavorable (2.71e-5)" "potential prognostic favorable (5.57e-6)" "unprognostic (1.27e-2)" "unprognostic (6.19e-2)" "unprognostic (1.57e-2)" "unprognostic (5.31e-3)" "unprognostic (2.17e-3)" "unprognostic (2.13e-1)" "unprognostic (1.08e-1)" "unprognostic (2.85e-1)" "unprognostic (3.43e-3)" "unprognostic (3.58e-2)" "potential prognostic unfavorable (2.08e-4)" "unprognostic (4.71e-3)" "unprognostic (2.65e-1)" "unprognostic (6.40e-2)" "unprognostic (1.76e-1)" "unprognostic (1.70e-2)" "unprognostic (2.77e-1)" "unprognostic (2.11e-1)" "unprognostic (2.98e-2)" "unprognostic (3.24e-1)" YIF1A "54TM, FinGER7, YIF1, YIF1P" ENSG00000174851 "Yip1 interacting factor homolog A, membrane trafficking protein" O95070 11 66284580-66289145 "Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 345.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014840, HPA076194" Enhanced Enhanced "Golgi apparatus,Vesicles" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 70: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 24: Non-specific - Unknown function" "Cluster 8: Non-specific - Secretory pathway" 81 "Golgi apparatus, Vesicles" "HPA014840: , HPA076194: " "unprognostic (3.92e-3)" "unprognostic (2.50e-3)" "unprognostic (1.87e-3)" "unprognostic (1.43e-3)" "unprognostic (2.18e-1)" "unprognostic (2.46e-1)" "unprognostic (7.45e-2)" "unprognostic (3.23e-1)" "unprognostic (1.01e-3)" "unprognostic (1.29e-2)" "unprognostic (1.51e-2)" "unprognostic (6.77e-3)" "unprognostic (3.84e-1)" "validated prognostic unfavorable (7.38e-4)" "validated prognostic unfavorable (1.23e-4)" "unprognostic (1.21e-3)" "potential prognostic unfavorable (8.85e-4)" "unprognostic (2.30e-1)" "unprognostic (2.65e-1)" "unprognostic (1.79e-1)" "unprognostic (9.65e-2)" "unprognostic (2.70e-1)" "unprognostic (5.17e-2)" "unprognostic (6.12e-2)" "unprognostic (1.43e-1)" "unprognostic (9.75e-2)" "unprognostic (1.96e-2)" "unprognostic (1.33e-1)" "unprognostic (1.23e-1)" "unprognostic (1.05e-1)" "unprognostic (2.64e-1)" YIF1B FinGER8 ENSG00000167645 "Yip1 interacting factor homolog B, membrane trafficking protein" Q5BJH7 19 38303558-38317273 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 116.2;Megakaryocytes: 148.4;Platelets: 253.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039328, HPA055257, HPA062675" Approved Supported "Golgi apparatus,Vesicles" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 47: Platelets - Hemostasis" 11 "Golgi apparatus, Vesicles" "HPA039328: , HPA055257: , HPA062675: " "unprognostic (1.70e-1)" "unprognostic (1.95e-2)" "unprognostic (1.01e-1)" "unprognostic (2.42e-2)" "unprognostic (3.19e-3)" "unprognostic (7.44e-2)" "unprognostic (1.99e-1)" "unprognostic (2.33e-1)" "unprognostic (2.52e-1)" "unprognostic (5.40e-3)" "potential prognostic unfavorable (8.79e-4)" "unprognostic (2.12e-2)" "unprognostic (1.84e-1)" "validated prognostic unfavorable (1.03e-5)" "validated prognostic unfavorable (6.17e-5)" "unprognostic (1.11e-1)" "unprognostic (1.34e-1)" "unprognostic (2.69e-3)" "unprognostic (8.68e-2)" "unprognostic (1.06e-1)" "unprognostic (2.04e-1)" "unprognostic (5.64e-2)" "unprognostic (1.29e-2)" "unprognostic (1.55e-2)" "unprognostic (1.56e-1)" "unprognostic (1.31e-1)" "unprognostic (3.38e-2)" "unprognostic (2.60e-1)" "unprognostic (3.39e-1)" "unprognostic (3.35e-2)" "unprognostic (1.41e-1)" YIPF1 "DJ167A19.1, FinGER1" ENSG00000058799 "Yip1 domain family member 1" Q9Y548 1 53851719-53889798 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 101.0;Esophageal apical cells: 92.4;Late spermatids: 92.8;Neutrophils: 98.4;Syncytiotrophoblasts: 168.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells, Heart muscle - Macrophages, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014716, HPA073931" Approved Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 27: Breast cancer - Unknown function" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 36 "Golgi apparatus" "Nucleoplasm, Plasma membrane" "HPA014716: , HPA073931: " "unprognostic (1.40e-1)" "unprognostic (3.51e-1)" "unprognostic (1.64e-2)" "unprognostic (3.34e-2)" "unprognostic (4.91e-2)" "unprognostic (1.80e-2)" "unprognostic (9.09e-3)" "potential prognostic unfavorable (8.42e-4)" "unprognostic (7.87e-2)" "unprognostic (3.07e-2)" "unprognostic (1.20e-2)" "unprognostic (1.50e-3)" "unprognostic (1.32e-1)" "unprognostic (1.89e-3)" "unprognostic (1.85e-1)" "unprognostic (7.54e-2)" "potential prognostic unfavorable (7.39e-4)" "unprognostic (4.41e-2)" "unprognostic (2.35e-1)" "unprognostic (1.64e-1)" "unprognostic (5.71e-2)" "unprognostic (3.24e-2)" "unprognostic (5.82e-2)" "unprognostic (1.25e-1)" "unprognostic (4.22e-1)" "unprognostic (5.90e-2)" "unprognostic (3.66e-1)" "unprognostic (8.77e-2)" "unprognostic (2.02e-1)" "unprognostic (6.03e-3)" "unprognostic (1.32e-1)" YIPF2 "FinGER2, MGC3262" ENSG00000130733 "Yip1 domain family member 2" Q9BWQ6 19 10922185-10928681 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epididymal principal cells: 157.0;Esophageal apical cells: 160.5;Extravillous trophoblasts: 168.5;Late primary spermatocytes: 279.5;Syncytiotrophoblasts: 250.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Lactotropes, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019902 Approved Approved "Golgi apparatus,Mitochondria" No No "Cluster 29: Non-specific - Unknown function" "Cluster 8: Pancreas - Proteolysis" "Cluster 44: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 8: Non-specific - Secretory pathway" 26 "Golgi apparatus, Mitochondria" "HPA019902: " "unprognostic (1.21e-1)" "unprognostic (3.55e-2)" "unprognostic (6.87e-2)" "unprognostic (2.41e-2)" "unprognostic (1.55e-2)" "unprognostic (5.88e-2)" "unprognostic (4.26e-2)" "unprognostic (2.26e-1)" "unprognostic (3.20e-1)" "unprognostic (7.32e-2)" "unprognostic (5.57e-2)" "potential prognostic unfavorable (7.33e-4)" "unprognostic (2.08e-1)" "unprognostic (6.21e-2)" "unprognostic (4.29e-3)" "unprognostic (9.19e-2)" "unprognostic (2.27e-2)" "unprognostic (1.17e-1)" "unprognostic (1.35e-1)" "unprognostic (1.83e-2)" "unprognostic (9.00e-2)" "unprognostic (2.80e-1)" "unprognostic (1.34e-1)" "unprognostic (1.20e-1)" "unprognostic (2.37e-1)" "unprognostic (1.56e-2)" "unprognostic (8.11e-2)" "unprognostic (6.76e-2)" "unprognostic (8.94e-3)" "unprognostic (4.06e-2)" "unprognostic (7.40e-2)" YIPF3 "C6orf109, dJ337H4.3, DKFZp566C243, FinGER3, KLIP1" ENSG00000137207 "Yip1 domain family member 3" Q9GZM5 6 43511832-43516985 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 342.2;Extravillous trophoblasts: 289.6;Syncytiotrophoblasts: 316.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014859, HPA063699" Supported Enhanced "Nucleoplasm,Golgi apparatus" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 12: Non-specific - Vasculature" "Cluster 28: Non-specific - Nuclear processes" "Cluster 8: Non-specific - Secretory pathway" 62 "Golgi apparatus" Nucleoplasm "HPA014859: , HPA063699: " "unprognostic (1.51e-1)" "unprognostic (4.56e-3)" "unprognostic (2.59e-2)" "unprognostic (2.13e-2)" "unprognostic (1.92e-1)" "potential prognostic unfavorable (9.47e-4)" "unprognostic (2.35e-1)" "unprognostic (2.69e-1)" "unprognostic (1.28e-1)" "unprognostic (1.11e-1)" "potential prognostic favorable (1.48e-4)" "unprognostic (1.90e-3)" "unprognostic (1.45e-1)" "unprognostic (1.59e-2)" "unprognostic (5.54e-3)" "unprognostic (6.44e-2)" "unprognostic (1.63e-2)" "unprognostic (7.64e-2)" "unprognostic (3.40e-1)" "unprognostic (1.12e-2)" "unprognostic (1.62e-1)" "unprognostic (2.44e-1)" "unprognostic (3.82e-1)" "unprognostic (1.89e-1)" "unprognostic (2.95e-1)" "unprognostic (8.73e-2)" "unprognostic (1.67e-2)" "unprognostic (4.35e-2)" "unprognostic (3.15e-2)" "unprognostic (1.40e-1)" "unprognostic (3.88e-2)" YIPF4 "FinGER4, MGC11061" ENSG00000119820 "Yip1 domain family member 4" Q9BSR8 2 32277904-32316594 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 312.6;Esophageal apical cells: 550.8;Neutrophils: 336.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017884 Supported Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 37: Neurons - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 24: Neutrophils - Innate immunity signal integration" 33 "Golgi apparatus" "Vesicles, Plasma membrane" "HPA017884: " "unprognostic (5.10e-2)" "unprognostic (1.73e-3)" "unprognostic (6.07e-2)" "unprognostic (6.63e-3)" "unprognostic (1.17e-2)" "unprognostic (2.40e-1)" "unprognostic (2.30e-1)" "unprognostic (5.10e-1)" "unprognostic (1.45e-1)" "unprognostic (1.70e-2)" "unprognostic (2.33e-3)" "unprognostic (5.94e-3)" "unprognostic (1.63e-1)" "unprognostic (2.07e-2)" "unprognostic (4.88e-3)" "unprognostic (2.19e-2)" "unprognostic (1.25e-1)" "unprognostic (9.77e-3)" "unprognostic (1.92e-1)" "unprognostic (3.98e-2)" "potential prognostic unfavorable (3.02e-4)" "unprognostic (1.21e-1)" "unprognostic (4.37e-2)" "unprognostic (1.68e-1)" "unprognostic (1.47e-2)" "unprognostic (2.34e-2)" "unprognostic (1.54e-2)" "unprognostic (1.51e-1)" "unprognostic (4.99e-1)" "unprognostic (5.03e-2)" "unprognostic (2.95e-1)" YIPF5 "FinGER5, SMAP-5" ENSG00000145817 "Yip1 domain family member 5" Q969M3 5 144158162-144170714 "Disease related genes, Human disease related genes, Predicted membrane proteins" "ER-Golgi transport, Protein transport, Transport" "Diabetes mellitus, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042338, HPA073622" Supported Supported "Nucleoplasm,Endoplasmic reticulum,Golgi apparatus,Vesicles" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 60: Stomach - Digestion" "Cluster 21: Non-specific - Metabolism" "Cluster 15: Kidney cancer - Membrane components" "Cluster 8: Non-specific - Secretory pathway" 49 "Endoplasmic reticulum, Golgi apparatus, Vesicles" Nucleoplasm "HPA042338: , HPA073622: " "unprognostic (1.14e-1)" "unprognostic (9.46e-3)" "unprognostic (1.18e-1)" "unprognostic (2.74e-3)" "unprognostic (9.01e-2)" "unprognostic (1.93e-1)" "unprognostic (2.02e-2)" "potential prognostic unfavorable (2.66e-4)" "unprognostic (2.77e-3)" "potential prognostic unfavorable (8.04e-4)" "potential prognostic favorable (2.33e-9)" "unprognostic (4.38e-2)" "unprognostic (2.21e-1)" "potential prognostic unfavorable (3.76e-4)" "unprognostic (1.69e-2)" "unprognostic (1.13e-1)" "unprognostic (1.04e-2)" "unprognostic (1.32e-3)" "unprognostic (7.68e-3)" "unprognostic (3.68e-1)" "unprognostic (2.55e-3)" "unprognostic (5.78e-3)" "unprognostic (9.54e-2)" "unprognostic (1.32e-1)" "unprognostic (8.13e-2)" "unprognostic (3.11e-3)" "unprognostic (1.61e-1)" "unprognostic (1.47e-1)" "unprognostic (4.65e-1)" "unprognostic (2.07e-2)" "unprognostic (1.87e-1)" YIPF6 "FinGER6, MGC21416" ENSG00000181704 "Yip1 domain family member 6" Q96EC8 X 68498562-68537282 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 215.6;Syncytiotrophoblasts: 404.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003720 Uncertain Approved Vesicles NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." 90 Vesicles "HPA003720: " "unprognostic (1.61e-1)" "unprognostic (1.05e-3)" "unprognostic (6.20e-2)" "unprognostic (3.43e-2)" "unprognostic (2.26e-2)" "unprognostic (6.56e-2)" "unprognostic (8.67e-2)" "unprognostic (1.83e-1)" "unprognostic (2.44e-2)" "unprognostic (1.50e-1)" "potential prognostic favorable (1.58e-5)" "unprognostic (1.35e-2)" "unprognostic (8.47e-2)" "unprognostic (1.89e-1)" "unprognostic (5.45e-2)" "unprognostic (1.80e-1)" "unprognostic (1.42e-1)" "unprognostic (2.91e-1)" "unprognostic (3.91e-1)" "unprognostic (9.39e-2)" "unprognostic (3.69e-3)" "unprognostic (1.84e-1)" "unprognostic (2.23e-3)" "unprognostic (6.65e-2)" "unprognostic (2.38e-1)" "unprognostic (7.64e-2)" "unprognostic (9.22e-2)" "unprognostic (2.05e-1)" "unprognostic (1.13e-1)" "unprognostic (2.11e-1)" "unprognostic (1.06e-1)" YIPF7 "FinGER9, FLJ39576" ENSG00000177752 "Yip1 domain family member 7" Q8N8F6 4 44622088-44678556 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 51 "skeletal muscle: 64.6;tongue: 20.0" "Cell type enriched" "Detected in many" 6 "Myonuclei: 113.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in single" "Glioblastoma Multiforme (TCGA): 1.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.0" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" "Region enriched" "Detected in single" 20 "cerebellum: 10.1" HPA030642 Uncertain NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 2: Neurons - Nucleosome" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" "HPA030642: " "unprognostic (2.91e-1)" "unprognostic (2.01e-3)" YJEFN3 "FLJ44968, hYjeF_N3-19p13.11" ENSG00000250067 "YjeF N-terminal domain containing 3" A6XGL0 19 19528861-19537581 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "brain: 202.9" "Cell type enriched" "Detected in many" 6 "Late spermatids: 977.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 5.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA060789 Enhanced Approved Mitochondria NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" Mitochondria "HPA060789: " "unprognostic (1.41e-1)" "unprognostic (9.00e-2)" "unprognostic (1.33e-1)" "unprognostic (5.73e-2)" "unprognostic (6.45e-2)" "unprognostic (3.00e-2)" "potential prognostic unfavorable (3.98e-4)" "unprognostic (9.51e-2)" "unprognostic (1.63e-1)" "unprognostic (3.38e-1)" YJU2 "CCDC94, FLJ10374" ENSG00000105248 "YJU2 splicing factor homolog" Q9BW85 19 4247080-4269088 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043606, HPA055675" Approved Supported Nucleoplasm NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 26 Nucleoplasm "HPA043606: , HPA055675: " "unprognostic (3.40e-2)" "unprognostic (2.05e-2)" "unprognostic (6.70e-2)" "unprognostic (3.13e-2)" "unprognostic (1.12e-1)" "unprognostic (4.89e-2)" "unprognostic (2.36e-2)" "unprognostic (3.96e-3)" "unprognostic (7.22e-2)" "unprognostic (3.07e-3)" "unprognostic (4.18e-2)" "unprognostic (1.03e-2)" "unprognostic (1.60e-1)" "unprognostic (1.29e-1)" "unprognostic (4.43e-2)" "unprognostic (2.25e-2)" "potential prognostic favorable (9.99e-4)" "unprognostic (1.08e-1)" "unprognostic (2.51e-1)" "unprognostic (6.18e-3)" "unprognostic (1.46e-1)" "unprognostic (3.32e-1)" "unprognostic (1.71e-1)" "unprognostic (7.29e-2)" "unprognostic (3.15e-1)" "unprognostic (5.60e-3)" "unprognostic (2.49e-2)" "unprognostic (1.08e-1)" "potential prognostic favorable (2.56e-4)" YJU2B "CCDC130, MGC10471" ENSG00000104957 "YJU2 splicing factor homolog B" P13994 19 13731760-13763296 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056977 Approved Approved Vesicles NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 64: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 23: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 39 Vesicles "HPA056977: " "unprognostic (7.83e-2)" "unprognostic (8.58e-2)" "unprognostic (2.16e-2)" "unprognostic (4.59e-2)" "unprognostic (2.43e-2)" "unprognostic (2.78e-2)" "unprognostic (2.63e-1)" "unprognostic (3.09e-2)" "potential prognostic favorable (9.57e-4)" "unprognostic (6.66e-2)" "unprognostic (2.26e-3)" "unprognostic (2.39e-1)" "unprognostic (2.10e-2)" "unprognostic (7.98e-3)" "unprognostic (9.09e-2)" "unprognostic (1.94e-2)" "unprognostic (3.10e-1)" "unprognostic (7.89e-2)" "unprognostic (2.59e-2)" "unprognostic (5.60e-2)" "unprognostic (1.19e-1)" "unprognostic (1.44e-3)" "unprognostic (5.67e-3)" "potential prognostic unfavorable (1.25e-4)" "unprognostic (9.01e-3)" "unprognostic (2.46e-3)" "unprognostic (2.06e-1)" "unprognostic (1.53e-2)" "unprognostic (5.39e-2)" "unprognostic (2.66e-1)" "unprognostic (8.99e-3)" YKT6 ENSG00000106636 "YKT6 v-SNARE homolog" O15498 7 44200959-44214294 "Essential proteins, Metabolic proteins, Predicted intracellular proteins, Transporters" "ER-Golgi transport, Protein transport, Transport" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 170.3;Extravillous trophoblasts: 85.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030817, HPA030818" Approved Approved Mitochondria,Cytosol No No 11000 "Cluster 45: Eosinophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 67: Non-specific - Unknown function" "Cluster 8: Non-specific - Secretory pathway" 37 Cytosol Mitochondria "HPA030817: , HPA030818: " "unprognostic (2.19e-3)" "unprognostic (1.31e-2)" "unprognostic (5.14e-1)" "unprognostic (7.84e-2)" "unprognostic (1.20e-1)" "unprognostic (3.80e-1)" "unprognostic (3.20e-2)" "unprognostic (8.87e-2)" "potential prognostic unfavorable (2.92e-4)" "unprognostic (1.02e-1)" "unprognostic (3.18e-3)" "unprognostic (3.44e-2)" "unprognostic (2.11e-1)" "validated prognostic unfavorable (1.39e-6)" "validated prognostic unfavorable (8.35e-5)" "potential prognostic unfavorable (3.58e-4)" "unprognostic (4.79e-3)" "unprognostic (3.71e-1)" "unprognostic (1.76e-1)" "potential prognostic unfavorable (7.53e-4)" "unprognostic (3.48e-1)" "unprognostic (1.12e-1)" "potential prognostic unfavorable (8.23e-4)" "unprognostic (2.99e-1)" "unprognostic (5.80e-2)" "unprognostic (2.36e-1)" "unprognostic (3.19e-1)" "unprognostic (1.22e-1)" "unprognostic (1.03e-1)" "unprognostic (4.21e-3)" "unprognostic (7.59e-3)" YLPM1 "C14orf170, PPP1R169, ZAP" ENSG00000119596 "YLP motif containing 1" P49750 14 74763316-74859435 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048070, HPA061123" Uncertain Supported "Nuclear speckles" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 21: Testis - Mixed function" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 7: Non-specific - Transcription" 43 "Nuclear speckles" "HPA048070: , HPA061123: " "unprognostic (1.16e-1)" "unprognostic (2.42e-1)" "unprognostic (9.92e-2)" "unprognostic (1.29e-1)" "unprognostic (2.98e-1)" "unprognostic (4.72e-2)" "unprognostic (4.96e-2)" "unprognostic (1.22e-2)" "unprognostic (2.18e-1)" "unprognostic (3.75e-3)" "potential prognostic favorable (2.01e-5)" "unprognostic (1.27e-3)" "unprognostic (2.77e-1)" "potential prognostic unfavorable (5.23e-5)" "unprognostic (9.11e-2)" "unprognostic (1.73e-1)" "unprognostic (1.77e-1)" "unprognostic (1.23e-1)" "unprognostic (6.56e-2)" "unprognostic (1.19e-1)" "unprognostic (1.12e-1)" "unprognostic (1.09e-2)" "unprognostic (9.35e-3)" "unprognostic (1.02e-1)" "unprognostic (6.71e-2)" "unprognostic (1.13e-1)" "unprognostic (6.40e-2)" "unprognostic (6.25e-2)" "unprognostic (1.74e-1)" "unprognostic (1.45e-1)" "unprognostic (4.32e-2)" YME1L1 YME1L ENSG00000136758 "YME1 like 1 ATPase" Q96TA2 10 27110111-27155266 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" HPA066953 Approved Supported "Nuclear bodies,Mitochondria" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 52: Non-specific - Mitochondria" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 13 Mitochondria "Nuclear bodies" "HPA066953: " "unprognostic (4.73e-2)" "unprognostic (2.14e-2)" "unprognostic (9.20e-3)" "unprognostic (2.50e-2)" "unprognostic (9.15e-2)" "unprognostic (3.81e-2)" "unprognostic (1.84e-1)" "potential prognostic favorable (9.54e-5)" "unprognostic (1.45e-1)" "unprognostic (4.31e-3)" "potential prognostic favorable (2.66e-6)" "unprognostic (3.06e-2)" "unprognostic (3.88e-2)" "potential prognostic unfavorable (1.02e-4)" "unprognostic (2.65e-3)" "unprognostic (8.05e-2)" "unprognostic (1.31e-2)" "unprognostic (3.69e-2)" "unprognostic (1.55e-1)" "unprognostic (6.77e-2)" "potential prognostic unfavorable (8.17e-4)" "unprognostic (2.97e-3)" "unprognostic (3.30e-2)" "unprognostic (6.43e-2)" "unprognostic (1.79e-1)" "unprognostic (1.30e-1)" "unprognostic (1.65e-1)" "unprognostic (1.32e-1)" "unprognostic (2.00e-1)" "unprognostic (6.28e-3)" "unprognostic (2.30e-1)" YOD1 "DKFZp451J1719, DUBA8, OTUD2" ENSG00000180667 "YOD1 deubiquitinase" Q5VVQ6 1 207043849-207052980 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway, Unfolded protein response" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 55.3" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 171.1;Endometrial luminal cells: 97.4;Erythrocytes: 165.3;Esophageal apical cells: 611.5;Late spermatids: 170.9;Platelets: 123.1" "Cell type enhanced" "Detected in all" "astrocyte: 45.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028400, HPA028439" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 100000 "Cluster 35: Neutrophils - Protein binding" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 84: Apical squamous epithelium - Cornification" 31 "Nucleoplasm, Plasma membrane, Cytosol" "HPA028400: , HPA028439: " "unprognostic (3.33e-1)" "unprognostic (2.97e-2)" "unprognostic (1.19e-1)" "unprognostic (1.30e-1)" "unprognostic (2.01e-1)" "unprognostic (6.74e-2)" "unprognostic (2.75e-2)" "unprognostic (1.17e-3)" "unprognostic (2.62e-2)" "unprognostic (2.09e-1)" "potential prognostic favorable (3.98e-4)" "unprognostic (1.71e-2)" "unprognostic (9.75e-2)" "unprognostic (2.80e-3)" "unprognostic (4.61e-2)" "unprognostic (2.98e-2)" "unprognostic (4.21e-2)" "unprognostic (2.46e-1)" "unprognostic (2.74e-1)" "unprognostic (9.44e-2)" "unprognostic (1.17e-2)" "unprognostic (6.01e-3)" "unprognostic (2.08e-2)" "unprognostic (4.98e-2)" "unprognostic (2.56e-1)" "unprognostic (2.54e-1)" "unprognostic (1.06e-3)" "unprognostic (5.09e-2)" "unprognostic (2.77e-2)" "unprognostic (7.83e-3)" "unprognostic (2.54e-2)" YPEL1 ENSG00000100027 "Yippee like 1" O60688 22 21697536-21735794 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in all" 5 "testis: 149.8" "Group enriched" "Detected in many" 9 "Early spermatids: 645.6;Late primary spermatocytes: 1129.3;Late spermatids: 1955.4" "Cell type enhanced" "Detected in all" "medium spiny neuron: 152.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Leukemia: 16.1" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030501, HPA045621" Uncertain NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 67: Testis - Mixed function" "Cluster 33: Neurons - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" "HPA030501: , HPA045621: " "unprognostic (2.46e-1)" "unprognostic (5.24e-2)" "unprognostic (2.99e-1)" "unprognostic (5.21e-2)" "unprognostic (3.39e-2)" "unprognostic (3.02e-1)" "unprognostic (5.35e-3)" "unprognostic (7.88e-3)" "potential prognostic favorable (2.03e-4)" "unprognostic (1.61e-1)" "potential prognostic favorable (1.52e-6)" "unprognostic (5.80e-3)" "unprognostic (1.58e-1)" "unprognostic (2.70e-1)" "unprognostic (1.17e-1)" "unprognostic (1.98e-2)" "unprognostic (1.05e-1)" "unprognostic (8.53e-2)" "unprognostic (5.09e-2)" "unprognostic (1.87e-1)" "unprognostic (1.98e-1)" "unprognostic (5.94e-2)" "unprognostic (2.74e-2)" "unprognostic (3.63e-1)" "unprognostic (1.42e-2)" "unprognostic (7.20e-2)" "unprognostic (1.72e-2)" "unprognostic (2.53e-1)" "unprognostic (3.48e-2)" "unprognostic (4.24e-2)" "unprognostic (3.04e-1)" YPEL2 FKSG4 ENSG00000175155 "Yippee like 2" Q96QA6 17 59331655-59401729 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 77.1" "Cell type enhanced" "Detected in many" "Myonuclei: 270.3;Oligodendrocytes: 314.6;Retinal horizontal cells: 516.9;Rod photoreceptor cells: 743.7" "Cell type enhanced" "Detected in all" "oligodendrocyte: 399.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "testis cancer: 32.7" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030501, HPA045621" Uncertain NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 5: Rhabdoid - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" 2 "HPA030501: , HPA045621: " "unprognostic (3.37e-2)" "unprognostic (1.27e-1)" "unprognostic (9.04e-2)" "unprognostic (1.45e-1)" "unprognostic (2.00e-1)" "unprognostic (5.50e-2)" "unprognostic (9.10e-2)" "unprognostic (1.19e-1)" "unprognostic (6.81e-2)" "unprognostic (1.05e-1)" "validated prognostic favorable (4.00e-7)" "validated prognostic favorable (4.92e-5)" "unprognostic (9.57e-2)" "unprognostic (6.18e-2)" "unprognostic (2.05e-2)" "unprognostic (2.70e-2)" "unprognostic (3.06e-2)" "unprognostic (8.48e-2)" "unprognostic (9.21e-2)" "unprognostic (4.12e-1)" "unprognostic (2.39e-2)" "unprognostic (5.26e-2)" "unprognostic (9.69e-3)" "unprognostic (3.37e-1)" "unprognostic (1.91e-1)" "unprognostic (3.42e-1)" "unprognostic (2.65e-2)" "unprognostic (2.20e-1)" "unprognostic (3.22e-1)" "unprognostic (7.17e-2)" "unprognostic (6.58e-2)" YPEL3 MGC10500 ENSG00000090238 "Yippee like 3" P61236 16 30092314-30096915 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 357.9;Neutrophils: 1044.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "basophil: 23.2;eosinophil: 31.1;neutrophil: 47.6" "Lineage enriched" "Detected in all" 8 "granulocytes: 47.6" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030501, HPA045621" Uncertain NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 24: Neutrophils - Innate immunity signal integration" "HPA030501: , HPA045621: " "unprognostic (8.95e-3)" "unprognostic (3.29e-1)" "unprognostic (1.92e-1)" "unprognostic (3.55e-2)" "unprognostic (9.65e-3)" "unprognostic (1.71e-1)" "unprognostic (2.62e-2)" "unprognostic (1.08e-2)" "unprognostic (2.03e-3)" "unprognostic (4.22e-2)" "unprognostic (1.98e-1)" "unprognostic (1.30e-1)" "unprognostic (7.72e-2)" "unprognostic (1.03e-1)" "unprognostic (2.38e-1)" "unprognostic (2.85e-2)" "unprognostic (2.75e-1)" "unprognostic (1.37e-2)" "unprognostic (6.51e-2)" "unprognostic (1.75e-1)" "unprognostic (3.88e-1)" "unprognostic (4.11e-3)" "unprognostic (1.04e-1)" "unprognostic (3.57e-1)" "unprognostic (4.93e-2)" "unprognostic (5.02e-2)" "unprognostic (5.11e-3)" "unprognostic (9.57e-2)" "unprognostic (1.00e-1)" "unprognostic (1.39e-1)" "unprognostic (2.68e-1)" YPEL4 FLJ30213 ENSG00000166793 "Yippee like 4" Q96NS1 11 57645087-57649944 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 38.8" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 18.8;Brain inhibitory neurons: 11.9;Early spermatids: 42.3;Erythrocyte progenitors: 10.1;Erythrocytes: 36.9;Lactotrophs: 10.1;Late spermatids: 20.1;Other brain neurons: 13.4;Ovarian stromal cells: 18.3;Retinal amacrine cells: 20.8;Retinal bipolar cells: 20.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Prostate - Fibroblasts, Stomach - Fibroblasts, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045621 Uncertain NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 47: Leukemia - Hemostasis" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" "HPA045621: " "unprognostic (2.06e-1)" "unprognostic (1.01e-1)" "unprognostic (2.28e-3)" "unprognostic (1.66e-3)" "potential prognostic favorable (5.92e-4)" "unprognostic (1.39e-2)" "unprognostic (1.11e-2)" "unprognostic (1.79e-2)" "unprognostic (6.78e-3)" "unprognostic (2.95e-2)" YPEL5 CGI-127 ENSG00000119801 "Yippee like 5" P62699 2 30146941-30160533 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "bone marrow: 413.6" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 651.5;Late spermatids: 930.8;Neutrophil progenitors: 549.6;Neutrophils: 929.7;Syncytiotrophoblasts: 538.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042809 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 53 Cytosol Nucleoplasm "HPA042809: " "unprognostic (2.62e-2)" "unprognostic (8.34e-3)" "unprognostic (2.13e-1)" "unprognostic (2.72e-2)" "unprognostic (4.44e-1)" "unprognostic (1.48e-1)" "unprognostic (6.31e-2)" "unprognostic (4.18e-2)" "unprognostic (2.13e-2)" "unprognostic (1.89e-1)" "potential prognostic favorable (3.50e-9)" "unprognostic (1.82e-1)" "unprognostic (2.86e-1)" "unprognostic (5.24e-2)" "unprognostic (5.17e-2)" "unprognostic (3.33e-2)" "unprognostic (6.96e-2)" "unprognostic (5.62e-2)" "unprognostic (1.10e-1)" "unprognostic (1.46e-1)" "unprognostic (8.63e-3)" "unprognostic (6.65e-2)" "unprognostic (2.61e-2)" "unprognostic (6.43e-2)" "unprognostic (5.96e-1)" "unprognostic (5.65e-2)" "unprognostic (1.87e-1)" "unprognostic (5.72e-2)" "unprognostic (2.64e-2)" "unprognostic (1.05e-1)" "unprognostic (1.80e-1)" YRDC "FLJ23476, IRIP, SUA5" ENSG00000196449 "YrdC N6-threonylcarbamoyltransferase domain containing" Q86U90 1 37802945-37808208 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 47.2" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 56.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 8 "basophil: 8.8" "Lineage enriched" "Detected in many" 8 "granulocytes: 8.8" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030147 Approved Approved Mitochondria NA NA "Cluster 18: Non-specific - Translation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 1: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 4 Mitochondria "HPA030147: " "unprognostic (1.51e-1)" "unprognostic (4.73e-3)" "unprognostic (2.59e-2)" "potential prognostic unfavorable (5.32e-4)" "unprognostic (1.11e-3)" "unprognostic (2.16e-1)" "unprognostic (1.73e-1)" "unprognostic (5.40e-2)" "unprognostic (1.55e-2)" "unprognostic (1.59e-2)" "unprognostic (1.48e-3)" "unprognostic (1.27e-1)" "unprognostic (2.13e-1)" "validated prognostic unfavorable (2.44e-6)" "validated prognostic unfavorable (4.14e-5)" "unprognostic (6.45e-2)" "unprognostic (5.26e-2)" "unprognostic (3.38e-1)" "unprognostic (1.19e-1)" "unprognostic (6.32e-2)" "unprognostic (1.72e-1)" "unprognostic (2.77e-1)" "unprognostic (1.69e-1)" "unprognostic (2.55e-1)" "unprognostic (9.96e-2)" "unprognostic (8.77e-2)" "unprognostic (1.82e-1)" "unprognostic (2.28e-2)" "unprognostic (1.46e-1)" "unprognostic (3.87e-2)" "unprognostic (1.48e-2)" YTHDC1 "KIAA1966, YT521, YT521-B" ENSG00000083896 "YTH domain containing 1" Q96MU7 4 68310387-68350090 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal basal cells: 147.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036462 Supported Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 102: Non-specific - Mixed function" 55 Nucleoplasm "Plasma membrane" "HPA036462: " "unprognostic (4.95e-2)" "unprognostic (2.69e-2)" "unprognostic (1.75e-1)" "unprognostic (2.93e-1)" "unprognostic (7.02e-2)" "unprognostic (3.32e-1)" "unprognostic (4.45e-2)" "unprognostic (8.47e-2)" "unprognostic (2.78e-2)" "unprognostic (1.98e-2)" "validated prognostic favorable (7.00e-5)" "validated prognostic favorable (3.06e-6)" "unprognostic (6.83e-3)" "unprognostic (3.21e-3)" "unprognostic (2.03e-1)" "unprognostic (1.76e-1)" "unprognostic (1.05e-1)" "unprognostic (3.55e-2)" "unprognostic (3.00e-2)" "unprognostic (2.63e-1)" "unprognostic (1.88e-1)" "unprognostic (1.34e-1)" "unprognostic (8.51e-3)" "unprognostic (8.18e-2)" "unprognostic (1.17e-2)" "unprognostic (8.28e-2)" "unprognostic (1.07e-1)" "unprognostic (8.74e-2)" "unprognostic (1.42e-1)" "unprognostic (1.02e-1)" "unprognostic (1.19e-1)" YTHDC2 "DKFZp564A186, FLJ10053, FLJ2194" ENSG00000047188 "YTH domain containing 2" Q9H6S0 5 113513694-113595285 "Enzymes, Predicted intracellular proteins" "Differentiation, Meiosis, Oogenesis, Spermatogenesis" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037364, HPA072678" Approved Approved "Nucleoplasm,Nuclear bodies,Cytoplasmic bodies" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 42: Retina - Visual perception" "Cluster 31: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 59 Nucleoplasm "Nuclear bodies, Cytoplasmic bodies" "HPA037364: , HPA072678: " "unprognostic (1.06e-2)" "unprognostic (5.27e-2)" "unprognostic (6.19e-2)" "unprognostic (3.77e-2)" "unprognostic (2.72e-2)" "unprognostic (1.84e-3)" "unprognostic (1.24e-1)" "unprognostic (2.08e-1)" "unprognostic (1.52e-2)" "unprognostic (1.55e-2)" "potential prognostic favorable (4.25e-5)" "unprognostic (1.90e-2)" "unprognostic (2.54e-1)" "unprognostic (1.97e-1)" "unprognostic (1.39e-2)" "unprognostic (1.67e-1)" "unprognostic (1.36e-1)" "unprognostic (7.69e-2)" "unprognostic (1.90e-1)" "unprognostic (6.16e-2)" "unprognostic (2.26e-2)" "unprognostic (1.50e-1)" "unprognostic (7.45e-2)" "unprognostic (1.55e-1)" "potential prognostic favorable (6.52e-4)" "unprognostic (1.01e-1)" "unprognostic (5.79e-2)" "unprognostic (1.39e-1)" "unprognostic (2.79e-1)" "unprognostic (9.86e-3)" "unprognostic (1.58e-1)" YTHDF1 "C20orf21, FLJ20391" ENSG00000149658 "YTH N6-methyladenosine RNA binding protein 1" Q9BYJ9 20 63195429-63216139 "Predicted intracellular proteins" Immunity RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 39: Astrocytes - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 17: Non-specific - RNA processing" 79 "unprognostic (8.75e-3)" "unprognostic (3.50e-3)" "unprognostic (5.80e-2)" "unprognostic (1.18e-1)" "unprognostic (4.08e-1)" "unprognostic (1.03e-1)" "unprognostic (1.14e-1)" "unprognostic (1.28e-1)" "unprognostic (1.01e-1)" "unprognostic (5.55e-3)" "unprognostic (5.92e-3)" "unprognostic (1.99e-1)" "unprognostic (2.15e-1)" "validated prognostic unfavorable (1.83e-5)" "validated prognostic unfavorable (9.03e-4)" "unprognostic (1.95e-1)" "unprognostic (4.37e-2)" "unprognostic (9.00e-2)" "unprognostic (2.54e-2)" "unprognostic (2.00e-1)" "unprognostic (1.02e-1)" "unprognostic (8.21e-2)" "unprognostic (2.49e-3)" "unprognostic (5.20e-2)" "unprognostic (2.71e-2)" "unprognostic (1.51e-2)" "unprognostic (1.25e-1)" "unprognostic (9.17e-2)" "unprognostic (2.26e-1)" "unprognostic (2.42e-3)" "unprognostic (2.22e-1)" YTHDF2 "CAHL, HGRG8, NY-REN-2" ENSG00000198492 "YTH N6-methyladenosine RNA binding protein 2" Q9Y5A9 1 28736621-28769775 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Host-virus interaction, Immunity, Innate immunity, Mitosis, Oogenesis, Spermatogenesis" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 317.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Lung - Alveolar cells type 2, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030063, HPA054080, HPA059621" Approved Enhanced "Cytosol,Cytoplasmic bodies" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 71 Cytosol "Cytoplasmic bodies" "HPA030063: , HPA054080: , HPA059621: " "unprognostic (2.64e-2)" "unprognostic (3.60e-2)" "unprognostic (9.93e-2)" "unprognostic (1.88e-1)" "unprognostic (1.35e-2)" "unprognostic (1.29e-1)" "unprognostic (9.68e-2)" "unprognostic (6.97e-3)" "unprognostic (2.38e-1)" "unprognostic (1.09e-2)" "potential prognostic favorable (7.45e-7)" "unprognostic (7.68e-3)" "unprognostic (1.49e-1)" "potential prognostic unfavorable (1.94e-9)" "unprognostic (3.69e-3)" "unprognostic (1.57e-1)" "unprognostic (7.03e-2)" "unprognostic (3.76e-1)" "unprognostic (1.29e-1)" "unprognostic (5.01e-2)" "unprognostic (4.04e-2)" "unprognostic (8.53e-2)" "unprognostic (6.31e-2)" "unprognostic (4.10e-3)" "unprognostic (3.83e-2)" "unprognostic (6.12e-2)" "unprognostic (1.06e-1)" "unprognostic (1.47e-1)" "unprognostic (3.39e-1)" "unprognostic (8.65e-2)" "unprognostic (3.95e-1)" YTHDF3 FLJ31657 ENSG00000185728 "YTH N6-methyladenosine RNA binding protein 3" Q7Z739 8 63168553-63212786 "Predicted intracellular proteins" "Host-virus interaction" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 332.3;Neutrophil progenitors: 407.3;Neutrophils: 863.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 33 "unprognostic (3.79e-2)" "unprognostic (2.67e-2)" "unprognostic (6.88e-2)" "unprognostic (7.11e-3)" "unprognostic (2.81e-1)" "unprognostic (1.30e-1)" "unprognostic (2.73e-1)" "unprognostic (1.52e-1)" "unprognostic (1.44e-1)" "unprognostic (1.63e-3)" "potential prognostic favorable (1.64e-5)" "unprognostic (1.35e-2)" "unprognostic (1.36e-1)" "unprognostic (7.01e-2)" "unprognostic (2.05e-1)" "unprognostic (1.12e-1)" "unprognostic (2.37e-1)" "unprognostic (1.47e-1)" "unprognostic (1.30e-1)" "unprognostic (1.05e-2)" "unprognostic (6.78e-2)" "unprognostic (9.47e-3)" "unprognostic (2.32e-2)" "unprognostic (1.85e-1)" "unprognostic (6.05e-2)" "unprognostic (9.71e-2)" "unprognostic (1.23e-1)" "unprognostic (1.12e-1)" "unprognostic (1.84e-1)" "unprognostic (7.15e-3)" "unprognostic (2.77e-1)" YWHAB YWHAA ENSG00000166913 "Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta" P31946 20 44885702-44908532 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1215.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003759, HPA007925, HPA011212, HPA061603, CAB080288, CAB080290" Enhanced Supported Cytosol NA NA 88000000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 14: Neurons - Synaptic function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 858 Cytosol "CAB003759: , CAB080288: , CAB080290: , HPA007925: , HPA011212: , HPA061603: " "unprognostic (9.87e-3)" "unprognostic (1.16e-3)" "unprognostic (1.20e-1)" "unprognostic (4.32e-2)" "unprognostic (2.70e-1)" "unprognostic (2.93e-1)" "unprognostic (2.37e-1)" "unprognostic (1.70e-2)" "unprognostic (9.90e-3)" "unprognostic (3.41e-2)" "potential prognostic favorable (8.61e-7)" "unprognostic (2.16e-1)" "unprognostic (4.09e-2)" "potential prognostic unfavorable (7.32e-6)" "unprognostic (7.57e-3)" "unprognostic (1.92e-2)" "unprognostic (4.26e-3)" "unprognostic (1.29e-2)" "unprognostic (1.44e-1)" "unprognostic (1.11e-1)" "unprognostic (4.40e-3)" "unprognostic (1.36e-2)" "unprognostic (3.19e-2)" "unprognostic (2.30e-1)" "unprognostic (1.68e-1)" "unprognostic (5.59e-3)" "unprognostic (1.62e-1)" "unprognostic (2.45e-1)" "unprognostic (5.81e-1)" "unprognostic (9.01e-2)" "unprognostic (1.87e-1)" YWHAE FLJ45465 ENSG00000108953 "Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon" P62258 17 1344275-1400222 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 238.3;Megakaryocytes: 191.6;Renal collecting duct intercalated cells: 173.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008445, CAB016200, CAB021109, CAB047350, HPA061603" Approved Supported Cytosol NA NA 96000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 102: Non-specific - Mixed function" 1077 Cytosol "CAB016200: , CAB021109: , CAB047350: , HPA008445: , HPA061603: " "unprognostic (2.52e-2)" "unprognostic (4.86e-2)" "potential prognostic unfavorable (3.76e-4)" "unprognostic (1.15e-1)" "unprognostic (1.45e-1)" "unprognostic (1.00e-1)" "unprognostic (2.68e-2)" "unprognostic (1.95e-2)" "unprognostic (3.07e-2)" "unprognostic (1.94e-3)" "potential prognostic favorable (1.27e-7)" "unprognostic (1.03e-2)" "unprognostic (2.01e-1)" "unprognostic (2.42e-3)" "unprognostic (3.96e-2)" "potential prognostic unfavorable (3.92e-4)" "unprognostic (6.70e-2)" "unprognostic (1.75e-1)" "unprognostic (2.55e-1)" "unprognostic (1.65e-1)" "unprognostic (2.07e-1)" "unprognostic (4.51e-2)" "unprognostic (2.26e-2)" "unprognostic (1.64e-1)" "unprognostic (8.75e-2)" "unprognostic (2.20e-2)" "unprognostic (3.77e-1)" "unprognostic (4.27e-2)" "unprognostic (2.04e-1)" "unprognostic (1.43e-1)" "unprognostic (1.91e-2)" YWHAG "14-3-3GAMMA, PPP1R170" ENSG00000170027 "Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma" P61981 7 76326799-76358991 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 355.0;skeletal muscle: 327.6" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013274, CAB018389, HPA026918, HPA061603" Approved Approved Supported Vesicles,Cytosol NA NA 68000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 39: Non-specific - Transcription" "Cluster 26: Keratinocytes - Keratinization" 1193 Cytosol Vesicles "CAB013274: , CAB018389: , HPA026918: , HPA061603: " "unprognostic (1.94e-2)" "unprognostic (1.50e-2)" "unprognostic (1.35e-1)" "potential prognostic unfavorable (2.92e-5)" "unprognostic (6.92e-2)" "unprognostic (1.40e-2)" "unprognostic (1.95e-2)" "unprognostic (2.61e-3)" "potential prognostic unfavorable (8.83e-4)" "unprognostic (2.51e-3)" "unprognostic (1.04e-3)" "unprognostic (4.60e-3)" "unprognostic (5.75e-2)" "unprognostic (9.37e-3)" "potential prognostic unfavorable (3.06e-5)" "validated prognostic unfavorable (2.86e-5)" "validated prognostic unfavorable (1.54e-4)" "unprognostic (1.72e-1)" "unprognostic (2.25e-1)" "unprognostic (2.91e-1)" "unprognostic (1.30e-1)" "potential prognostic unfavorable (9.03e-4)" "unprognostic (5.97e-3)" "unprognostic (1.99e-2)" "unprognostic (2.68e-1)" "unprognostic (3.69e-1)" "unprognostic (9.77e-2)" "unprognostic (1.39e-1)" "unprognostic (1.70e-1)" "unprognostic (8.98e-2)" "unprognostic (2.06e-1)" YWHAH YWHA1 ENSG00000128245 "Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta" Q04917 22 31944522-31957603 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "blood vessel: 288.0;brain: 728.3" "Group enriched" "Detected in many" 5 "Megakaryocytes: 1013.8;Platelets: 2830.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025918, HPA061603" Uncertain Approved "Nucleoplasm,Nucleoli rim,Cytosol" NA NA 54000000 "Cluster 25: Non-specific - Unknown function" "Cluster 73: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 66: Non-specific - Mitochondria" "Cluster 47: Platelets - Hemostasis" 711 Cytosol "Nucleoplasm, Nucleoli rim" "CAB025918: , HPA061603: " "unprognostic (3.21e-2)" "unprognostic (1.07e-1)" "unprognostic (9.66e-2)" "unprognostic (8.48e-2)" "unprognostic (1.32e-1)" "unprognostic (8.81e-2)" "unprognostic (3.50e-2)" "unprognostic (1.11e-1)" "unprognostic (6.51e-2)" "unprognostic (3.15e-1)" "potential prognostic favorable (2.37e-4)" "unprognostic (5.65e-3)" "unprognostic (4.61e-2)" "potential prognostic unfavorable (9.59e-5)" "unprognostic (2.62e-3)" "unprognostic (1.85e-2)" "unprognostic (2.91e-2)" "unprognostic (1.65e-1)" "unprognostic (4.33e-1)" "unprognostic (8.31e-2)" "unprognostic (3.49e-1)" "unprognostic (1.35e-1)" "unprognostic (9.92e-2)" "unprognostic (5.93e-2)" "unprognostic (1.60e-2)" "unprognostic (3.68e-1)" "unprognostic (2.18e-1)" "unprognostic (1.50e-1)" "unprognostic (1.95e-1)" "unprognostic (3.07e-1)" "unprognostic (2.88e-1)" YWHAQ "14-3-3, HS1" ENSG00000134308 "Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta" P27348 2 9583967-9630997 "Plasma proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skeletal muscle - Endothelial cells, Skin - Outer root sheath cells, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007925, CAB010286, HPA061603" Approved Supported "Nucleoplasm,Nucleoli rim,Cytosol" NA NA 71000000 "Cluster 1: T-cells - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 20: Non-specific - Transcription regulation" 554 Cytosol "Nucleoplasm, Nucleoli rim" "CAB010286: , HPA007925: , HPA061603: " "unprognostic (6.65e-3)" "unprognostic (1.04e-2)" "unprognostic (2.01e-2)" "unprognostic (5.54e-2)" "unprognostic (4.44e-2)" "unprognostic (1.79e-1)" "unprognostic (7.87e-2)" "unprognostic (5.77e-2)" "unprognostic (6.05e-3)" "potential prognostic unfavorable (8.30e-5)" "potential prognostic favorable (8.28e-6)" "unprognostic (8.64e-2)" "unprognostic (1.04e-1)" "validated prognostic unfavorable (2.14e-5)" "validated prognostic unfavorable (6.34e-7)" "unprognostic (2.60e-3)" "unprognostic (5.24e-2)" "unprognostic (1.21e-1)" "unprognostic (7.47e-2)" "unprognostic (2.21e-1)" "unprognostic (1.70e-1)" "unprognostic (9.97e-2)" "potential prognostic unfavorable (2.27e-4)" "unprognostic (8.39e-2)" "unprognostic (8.71e-2)" "unprognostic (1.39e-1)" "unprognostic (1.16e-1)" "unprognostic (2.52e-2)" "unprognostic (1.86e-1)" "unprognostic (1.67e-1)" "unprognostic (3.20e-3)" YWHAZ "14-3-3-zeta, KCIP-1, YWHAD" ENSG00000164924 "Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta" P63104 8 100916523-100953388 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 2310.1;Late spermatids: 3159.1;Neutrophils: 1644.3;Platelets: 1779.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005065, HPA061603" Approved Supported "Nucleoplasm,Nucleoli rim,Cytosol" NA NA 330000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 40: Non-specific - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 1066 Cytosol "Nucleoplasm, Nucleoli rim" "CAB005065: , HPA061603: " "unprognostic (8.17e-2)" "unprognostic (1.11e-3)" "unprognostic (1.74e-1)" "unprognostic (1.49e-1)" "unprognostic (3.48e-2)" "unprognostic (3.22e-2)" "unprognostic (3.15e-2)" "unprognostic (1.07e-1)" "unprognostic (4.54e-2)" "unprognostic (7.66e-2)" "potential prognostic favorable (3.10e-4)" "unprognostic (2.67e-1)" "potential prognostic unfavorable (8.80e-4)" "validated prognostic unfavorable (1.49e-4)" "validated prognostic unfavorable (6.36e-4)" "potential prognostic unfavorable (1.33e-4)" "unprognostic (2.44e-3)" "unprognostic (5.79e-2)" "unprognostic (2.28e-1)" "unprognostic (1.83e-2)" "potential prognostic unfavorable (1.93e-4)" "validated prognostic unfavorable (3.44e-4)" "validated prognostic unfavorable (1.48e-4)" "unprognostic (2.19e-2)" "unprognostic (1.06e-1)" "unprognostic (1.04e-1)" "unprognostic (2.40e-1)" "unprognostic (3.47e-1)" "unprognostic (3.70e-1)" "unprognostic (1.68e-1)" "unprognostic (3.30e-2)" YY1 "DELTA, INO80S, NF-E1, UCRBP, YIN-YANG-1" ENSG00000100811 "YY1 transcription factor" P25490 14 100238298-100282788 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, DNA damage, DNA recombination, DNA repair, Spermatogenesis, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000597, HPA001119, CAB009392" Supported Supported "Nucleoplasm,Nucleoli fibrillar center,Nuclear bodies" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 34: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 17: Non-specific - RNA processing" 176 Nucleoplasm "Nucleoli fibrillar center, Nuclear bodies" "CAB009392: , HPA000597: , HPA001119: " "unprognostic (6.75e-2)" "unprognostic (1.15e-1)" "unprognostic (4.86e-3)" "unprognostic (2.61e-1)" "unprognostic (1.30e-1)" "unprognostic (8.13e-2)" "unprognostic (1.94e-2)" "unprognostic (1.76e-1)" "unprognostic (3.38e-2)" "unprognostic (6.59e-2)" "unprognostic (1.55e-3)" "unprognostic (1.68e-2)" "unprognostic (1.65e-2)" "potential prognostic unfavorable (1.15e-4)" "unprognostic (2.32e-2)" "potential prognostic unfavorable (4.76e-4)" "unprognostic (1.31e-1)" "unprognostic (6.67e-2)" "unprognostic (8.73e-2)" "unprognostic (9.65e-2)" "potential prognostic unfavorable (1.79e-4)" "potential prognostic unfavorable (5.50e-4)" "unprognostic (1.02e-3)" "unprognostic (3.91e-2)" "unprognostic (3.08e-1)" "unprognostic (3.24e-2)" "unprognostic (4.82e-2)" "unprognostic (1.14e-2)" "unprognostic (4.21e-1)" "unprognostic (2.07e-1)" "unprognostic (2.46e-1)" YY1AP1 "HCCA2, YAP, YY1AP" ENSG00000163374 "YY1 associated protein 1" Q9H869 1 155659443-155689000 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pancreas - Endothelial cells, Testis - Early spermatids" "HPA006986, HPA064249" Uncertain Approved "Nucleoli fibrillar center" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 24: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 12 "Nucleoli fibrillar center" "HPA006986: , HPA064249: " "unprognostic (1.40e-1)" "unprognostic (2.92e-1)" "unprognostic (4.53e-1)" "unprognostic (5.69e-1)" "unprognostic (1.92e-1)" "unprognostic (1.55e-1)" "unprognostic (7.99e-2)" "unprognostic (4.27e-3)" "unprognostic (1.12e-1)" "unprognostic (1.49e-2)" "unprognostic (2.67e-3)" "unprognostic (2.42e-3)" "unprognostic (1.63e-2)" "unprognostic (3.52e-3)" "unprognostic (1.46e-2)" "unprognostic (1.43e-1)" "unprognostic (2.26e-3)" "unprognostic (3.58e-2)" "unprognostic (2.58e-1)" "unprognostic (1.72e-1)" "unprognostic (1.88e-1)" "unprognostic (3.41e-1)" "unprognostic (1.36e-1)" "unprognostic (7.60e-2)" "unprognostic (7.49e-2)" "unprognostic (3.76e-2)" "unprognostic (5.04e-2)" "unprognostic (3.94e-2)" "unprognostic (1.84e-1)" "unprognostic (1.54e-1)" "unprognostic (2.37e-2)" YY2 ZNF631 ENSG00000230797 "YY2 transcription factor" O15391 X 21855987-21858740 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 5.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "HPA000597, HPA001119, HPA030335" Enhanced Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 25: Non-specific - Transcription" "Cluster 36: Non-specific - mRNA processing" 4 "Nucleoplasm, Nuclear bodies" "HPA000597: , HPA001119: , HPA030335: " "unprognostic (1.79e-1)" "unprognostic (4.78e-2)" "unprognostic (4.48e-1)" "unprognostic (6.99e-2)" "unprognostic (9.54e-2)" "unprognostic (6.06e-3)" "unprognostic (1.08e-1)" "unprognostic (1.51e-1)" "unprognostic (5.96e-2)" "unprognostic (2.15e-1)" "unprognostic (2.70e-1)" "unprognostic (1.57e-1)" "unprognostic (1.10e-1)" "unprognostic (5.91e-3)" "potential prognostic unfavorable (7.34e-4)" "unprognostic (1.76e-1)" "unprognostic (1.75e-2)" "unprognostic (2.78e-1)" "unprognostic (1.40e-1)" "unprognostic (8.36e-3)" "unprognostic (6.09e-2)" "unprognostic (1.77e-1)" "unprognostic (1.26e-3)" "unprognostic (6.76e-2)" "unprognostic (3.00e-1)" "unprognostic (4.48e-2)" "unprognostic (3.09e-2)" "unprognostic (4.68e-2)" ZACN "L2, LGICZ, LGICZ1, ZAC, ZAC1" ENSG00000186919 "Zinc activated ion channel" Q401N2 17 76071961-76083666 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Cardiomyocytes: 56.1;Epicardial cells: 91.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 19 "unprognostic (9.80e-3)" "potential prognostic favorable (8.95e-6)" "unprognostic (3.32e-3)" ZAN ENSG00000146839 Zonadhesin Q9Y493 7 100733595-100797797 "Essential proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 12.1;Early primary spermatocytes: 15.6;Early spermatids: 17.4;Late primary spermatocytes: 28.3;Late spermatids: 43.5;Retinal ganglion cells: 11.6;Syncytiotrophoblasts: 22.4" "Low cell type specificity" "Detected in some" "Cancer enriched" "Detected in single" 10 "Testicular Germ Cell Tumor (TCGA): 1.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 63: Cytotrophoblasts - Basic cellular functions" "unprognostic (4.77e-1)" ZAP70 "SRK, STD, ZAP-70" ENSG00000115085 "Zeta chain of T cell receptor associated protein kinase 70" P43403 2 97713576-97739862 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Adaptive immunity, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 22.6;lymphoid tissue: 74.4" "Cell type enhanced" "Detected in some" "Innate lymphoid cells: 30.0;Neutrophil progenitors: 10.4;NK-cells: 127.3;T-cells: 86.8;Thymocytes: 40.7" "Cell type enriched" "Detected in some" 18 "leukocyte: 123.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 41 "gdT-cell: 137.8;MAIT T-cell: 93.5;memory CD4 T-cell: 71.8;memory CD8 T-cell: 108.1;naive CD4 T-cell: 50.8;naive CD8 T-cell: 80.2;NK-cell: 112.8;T-reg: 80.4" "Group enriched" "Detected in many" 56 "NK-cells: 112.8;T-cells: 137.8" "Group enriched" "Detected in some" 4 "Leukemia: 39.6;lymphoma: 10.7;Rhabdoid: 13.3" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Minor Salivary Gland - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Skeletal muscle - Fibroblasts, Spleen - T-cells, Stomach - T-cells, Thyroid gland - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002625, HPA003134" Enhanced NA NA 3500 "Cluster 1: T-cells - Unknown function" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 38: Sub-cortical - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 31 "CAB002625: , HPA003134: " "unprognostic (1.19e-1)" "unprognostic (4.51e-3)" "unprognostic (2.92e-2)" "potential prognostic favorable (1.96e-4)" "unprognostic (4.23e-2)" "unprognostic (7.47e-2)" "unprognostic (9.07e-2)" "potential prognostic favorable (2.33e-5)" "unprognostic (4.29e-2)" "unprognostic (1.01e-2)" "unprognostic (6.20e-2)" "unprognostic (1.25e-1)" "unprognostic (4.78e-3)" "potential prognostic favorable (1.27e-4)" "unprognostic (3.34e-3)" "unprognostic (1.08e-1)" "unprognostic (2.62e-1)" "unprognostic (1.01e-1)" "unprognostic (4.07e-2)" "unprognostic (1.30e-2)" "unprognostic (1.89e-2)" "unprognostic (1.74e-2)" "unprognostic (1.92e-1)" "unprognostic (3.91e-2)" "unprognostic (6.02e-3)" "unprognostic (7.14e-2)" "unprognostic (1.42e-1)" "unprognostic (3.05e-1)" "unprognostic (1.95e-1)" "unprognostic (3.12e-1)" ZAR1 Z3CXXC6 ENSG00000182223 "Zygote arrest 1" Q86SH2 4 48490252-48494389 "Plasma proteins, Predicted intracellular proteins" "Differentiation, Oogenesis" "Developmental protein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "testis: 1.3" "Cell type enriched" "Detected in some" 10 "Oocytes: 115.1" "Cell type enhanced" "Detected in single" "CGE interneuron: 1.6" "Not detected" "Not detected" "Region enhanced" "Detected in many" "midbrain: 7.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 9 "Neuroblastoma: 3.4" "Pituitary gland - Thyrotropes, Skin - Hair cortex cells, Skin - Inner root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" "Region enhanced" "Detected in some" "midbrain: 2.7" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 41: Oocytes - Oogenesis" 1 "unprognostic (1.32e-2)" ZAR1L Z3CXXC7 ENSG00000189167 "Zygote arrest 1 like" A6NP61 13 32303699-32315363 "Predicted intracellular proteins" "Differentiation, Oogenesis" "Developmental protein, RNA-binding" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 14 "Oocytes: 55.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA039540, HPA041319" Uncertain Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 46: Lymphoma - Humoral immune response" "Cluster 41: Oocytes - Oogenesis" Nucleoplasm "Nuclear speckles" "HPA039540: , HPA041319: " ZBBX FLJ23049 ENSG00000169064 "Zinc finger B-box domain containing" A8MT70 3 167239843-167407874 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "choroid plexus: 12.9;fallopian tube: 21.8;testis: 33.6" "Group enriched" "Detected in some" 6 "Choroid plexus epithelial cells: 392.5;Early spermatids: 431.4;Endometrial ciliated cells: 278.0;Ependymal cells: 1090.3;Epididymal efferent duct ciliated cells: 322.8;Fallopian tube ciliated cells: 395.6;Late primary spermatocytes: 315.2;Late spermatids: 356.1;Respiratory ciliated cells: 716.7" "Group enriched" "Detected in many" 8 "choroid plexus epithelial cell: 344.1;ependymal cell: 1171.6" "Cancer enhanced" "Detected in single" "Uterine Corpus Endometrial Carcinoma (TCGA): 1.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 1.3;testis cancer: 1.2" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA036327, HPA036328" Enhanced Approved "Golgi apparatus" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" "Golgi apparatus" "HPA036327: , HPA036328: " "unprognostic (3.61e-1)" "unprognostic (2.43e-1)" "unprognostic (9.61e-2)" "unprognostic (3.97e-2)" "unprognostic (3.14e-2)" ZBED1 "ALTE, DREF, hDREF, KIAA0785, TRAMP" ENSG00000214717 "Zinc finger BED-type containing 1" O96006 X 2486414-2500976 "Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation, Ubl conjugation pathway" "DNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 67.6" "Cell type enriched" "Detected in single" 6 "Thymic myoid cells: 2.7" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077591 Approved Approved "Nucleoplasm,Nuclear membrane,Centrosome" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 24: Non-specific - Transcription" "Cluster 19: Astrocytes - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 47 "Nucleoplasm, Centrosome" "Nuclear membrane" "HPA077591: " "unprognostic (2.60e-1)" "unprognostic (7.23e-2)" "unprognostic (1.90e-1)" "unprognostic (8.77e-2)" "unprognostic (6.16e-2)" "unprognostic (2.37e-1)" "unprognostic (1.59e-1)" "unprognostic (1.80e-2)" "unprognostic (1.69e-1)" "potential prognostic favorable (1.82e-6)" "unprognostic (2.17e-2)" "unprognostic (1.32e-1)" "unprognostic (7.38e-2)" "unprognostic (1.54e-1)" "unprognostic (1.98e-2)" "unprognostic (1.02e-1)" "unprognostic (2.62e-1)" "unprognostic (7.55e-2)" "unprognostic (2.70e-1)" "unprognostic (1.17e-1)" "potential prognostic favorable (4.21e-4)" "unprognostic (1.83e-1)" "unprognostic (2.87e-2)" "unprognostic (1.64e-1)" "unprognostic (8.63e-2)" "unprognostic (4.21e-2)" "unprognostic (1.15e-1)" "unprognostic (3.24e-2)" "unprognostic (7.12e-2)" ZBED2 MGC10796 ENSG00000177494 "Zinc finger BED-type containing 2" Q9BTP6 3 111592900-111595346 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 44.4;thyroid gland: 66.5" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 61.0;Basal keratinocytes: 11.8;Esophageal apical cells: 156.4;Esophageal basal cells: 12.4;Fallopian tube ciliated cells: 47.5;Medullary thymic epithelial cells: 40.8;Ocular epithelial cells: 11.3;Suprabasal keratinocytes: 24.0" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "Thyroid Carcinoma (TCGA): 101.1" "Region enriched" "Detected in single" 5 "basal ganglia: 1.0" "Immune cell enhanced" "Detected in some" "naive B-cell: 2.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Pituitary gland - Thyrotropes" "Not detected" "Not detected" HPA029786 Approved "Nuclear bodies,Mitochondria,Cytosol" No No "Cluster 14: Non-specific - Unknown function" "Cluster 80: Thymus - Adaptive immune response" "Cluster 33: Neurons - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 1 "Mitochondria, Cytosol" "Nuclear bodies" "HPA029786: " "unprognostic (4.07e-2)" "unprognostic (1.02e-1)" "unprognostic (3.11e-1)" "unprognostic (3.93e-2)" "unprognostic (4.93e-3)" "unprognostic (2.87e-1)" "unprognostic (1.48e-3)" "unprognostic (1.53e-1)" "unprognostic (2.04e-1)" "unprognostic (4.24e-2)" "unprognostic (2.85e-2)" "unprognostic (1.07e-1)" "unprognostic (1.98e-1)" "validated prognostic unfavorable (6.03e-4)" "validated prognostic unfavorable (4.39e-4)" "unprognostic (2.54e-3)" "unprognostic (4.11e-1)" "unprognostic (1.92e-2)" "unprognostic (1.37e-1)" "unprognostic (1.24e-1)" "unprognostic (3.91e-1)" ZBED3 MGC15435 ENSG00000132846 "Zinc finger BED-type containing 3" Q96IU2 5 77072072-77087285 "Predicted intracellular proteins, Predicted secreted proteins, Transcription factors" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" HPA055995 Approved Approved "Nucleoplasm,Plasma membrane" "Secreted to blood" Other NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 11: White matter - Signal transduction" "Cluster 6: Leukemia - Signal transduction" "Cluster 89: Adipocytes - Lipid metabolism" "Plasma membrane" Nucleoplasm "HPA055995: " "potential prognostic favorable (3.61e-4)" "unprognostic (2.23e-1)" "unprognostic (1.42e-1)" "unprognostic (9.30e-2)" "unprognostic (5.53e-2)" "unprognostic (2.52e-2)" "unprognostic (6.01e-2)" "unprognostic (1.49e-1)" "unprognostic (6.00e-2)" "unprognostic (4.38e-2)" "potential prognostic favorable (2.59e-6)" "unprognostic (1.87e-3)" "unprognostic (2.97e-3)" "unprognostic (3.74e-1)" "unprognostic (1.35e-1)" "unprognostic (9.79e-2)" "unprognostic (4.45e-2)" "unprognostic (1.35e-1)" "unprognostic (5.74e-2)" "unprognostic (6.09e-2)" "unprognostic (3.79e-1)" "unprognostic (1.65e-2)" "unprognostic (1.72e-1)" "unprognostic (1.00e-1)" "unprognostic (8.98e-3)" "unprognostic (2.26e-1)" "unprognostic (3.48e-2)" "unprognostic (1.13e-1)" "unprognostic (7.90e-2)" "unprognostic (9.96e-2)" "unprognostic (8.36e-2)" ZBED4 KIAA0637 ENSG00000100426 "Zinc finger BED-type containing 4" O75132 22 49853844-49890080 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Innate lymphoid cells: 145.6;NK-cells: 102.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" HPA045341 Approved Supported Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 15: Non-specific - Transcription" "Cluster 66: Non-specific - Mitochondria" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 1 Nucleoplasm "HPA045341: " "unprognostic (1.91e-1)" "unprognostic (5.12e-2)" "unprognostic (1.18e-1)" "unprognostic (1.01e-2)" "unprognostic (2.37e-2)" "unprognostic (3.02e-1)" "unprognostic (2.37e-2)" "unprognostic (1.95e-2)" "unprognostic (1.89e-1)" "unprognostic (3.17e-1)" "unprognostic (5.86e-3)" "unprognostic (1.85e-1)" "unprognostic (1.92e-1)" "unprognostic (1.35e-3)" "unprognostic (2.08e-2)" "unprognostic (5.20e-2)" "unprognostic (6.44e-2)" "unprognostic (2.00e-1)" "unprognostic (4.70e-3)" "unprognostic (3.70e-3)" "unprognostic (2.78e-2)" "unprognostic (3.86e-2)" "unprognostic (1.25e-2)" "unprognostic (4.68e-2)" "potential prognostic favorable (4.60e-4)" "unprognostic (9.56e-2)" "unprognostic (2.70e-1)" "unprognostic (5.50e-2)" "unprognostic (1.07e-1)" "unprognostic (1.53e-2)" "unprognostic (1.34e-1)" ZBED5 Buster1 ENSG00000236287 "Zinc finger BED-type containing 5" Q49AG3 11 10812074-10858796 "Predicted intracellular proteins, Transcription factors" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 243.8;Oligodendrocytes: 146.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pancreas - Endothelial cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "HPA048472, HPA050994" Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 49: Non-specific - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 24: Non-specific - Unknown function" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" "Golgi apparatus" "Nucleoplasm, Nucleoli fibrillar center" "HPA048472: , HPA050994: " "unprognostic (2.24e-1)" "unprognostic (4.70e-2)" "unprognostic (3.73e-1)" "unprognostic (3.06e-2)" "unprognostic (4.40e-3)" "unprognostic (1.10e-1)" "unprognostic (4.65e-1)" "unprognostic (3.85e-1)" "unprognostic (5.36e-2)" "unprognostic (3.04e-2)" "unprognostic (1.05e-2)" "unprognostic (7.21e-3)" "unprognostic (4.54e-3)" "potential prognostic unfavorable (1.97e-4)" "unprognostic (6.67e-2)" "unprognostic (1.92e-2)" "unprognostic (9.68e-2)" "unprognostic (1.81e-1)" "unprognostic (4.17e-1)" "unprognostic (2.19e-1)" "unprognostic (3.00e-2)" "unprognostic (1.61e-1)" "unprognostic (3.37e-2)" "unprognostic (1.19e-2)" "potential prognostic favorable (5.69e-4)" "unprognostic (1.38e-1)" "unprognostic (1.09e-2)" "unprognostic (1.04e-1)" "unprognostic (1.34e-1)" "unprognostic (1.51e-1)" "unprognostic (4.52e-2)" ZBED6 ENSG00000257315 "Zinc finger BED-type containing 6" P86452 1 203795623-203854124 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Kidney - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068807 Supported "Nucleoplasm,Centriolar satellite" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 45: Non-specific - Nuclear processes" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" Nucleoplasm "Centriolar satellite" "HPA068807: " "unprognostic (5.35e-2)" "unprognostic (1.62e-1)" "unprognostic (9.05e-2)" "unprognostic (1.32e-2)" "unprognostic (1.54e-1)" "unprognostic (3.04e-1)" "unprognostic (2.20e-2)" "validated prognostic favorable (6.14e-5)" "validated prognostic favorable (6.84e-4)" "unprognostic (8.33e-2)" "unprognostic (1.03e-1)" "unprognostic (6.91e-2)" "unprognostic (1.81e-1)" "unprognostic (2.97e-1)" "unprognostic (1.84e-2)" "unprognostic (2.95e-1)" "unprognostic (9.82e-3)" "unprognostic (3.98e-3)" "unprognostic (8.26e-3)" "unprognostic (3.17e-2)" "unprognostic (1.33e-1)" "unprognostic (1.44e-1)" "unprognostic (3.86e-2)" "unprognostic (1.39e-2)" "unprognostic (1.02e-1)" "unprognostic (1.04e-2)" ZBED8 "Buster3, C5orf54" ENSG00000221886 "Zinc finger BED-type containing 8" Q8IZ13 5 160393148-160400054 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 31.7;Corticotrophs: 18.5;Lactotrophs: 18.1;Thyrotrophs: 19.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "HPA045445, HPA055817" Approved Enhanced Nucleoplasm NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 65: Brain - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 3 Nucleoplasm "HPA045445: , HPA055817: " "unprognostic (1.92e-3)" "unprognostic (1.53e-2)" "unprognostic (3.67e-1)" "potential prognostic unfavorable (8.08e-4)" "unprognostic (1.33e-2)" "unprognostic (2.28e-1)" "unprognostic (2.25e-1)" "unprognostic (9.68e-2)" "unprognostic (1.17e-1)" "unprognostic (6.17e-3)" "unprognostic (1.26e-1)" "unprognostic (8.17e-2)" "potential prognostic unfavorable (1.00e-4)" "unprognostic (2.14e-1)" "unprognostic (1.22e-1)" "unprognostic (2.66e-1)" "unprognostic (1.12e-1)" "unprognostic (9.83e-2)" "unprognostic (1.11e-1)" "potential prognostic favorable (3.71e-4)" "potential prognostic unfavorable (6.29e-4)" "unprognostic (6.05e-2)" "potential prognostic favorable (1.33e-4)" "unprognostic (1.02e-1)" "unprognostic (6.35e-3)" "unprognostic (2.76e-1)" "unprognostic (1.64e-1)" "unprognostic (2.98e-1)" "unprognostic (1.18e-1)" ZBED9 "Buster4, FLJ31087, KIAA1925, SCAND3, ZFP38-L, ZNF305P2, ZNF452" ENSG00000232040 "Zinc finger BED-type containing 9" Q6R2W3 6 28570535-28616212 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 8.1" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 7.5;Brain inhibitory neurons: 7.8;Distal convoluted tubule cells: 3.0;Early primary spermatocytes: 2.8;Late primary spermatocytes: 4.5;Loop of henle epithelial cells: 3.9;Other brain neurons: 8.2;Papillary tip epithelial cells: 2.6;Proximal tubule cells: 2.4;Renal collecting duct principal cells: 6.0;Renal connecting tubule cells: 3.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose visceral - Mesothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007246 Uncertain Approved "Nucleoplasm,Nucleoli,Golgi apparatus" NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 2: Neurons - Nucleosome" "Cluster 47: Leukemia - Hemostasis" "Cluster 98: Neurons - Neurotransmission & signaling" Nucleoli "Nucleoplasm, Golgi apparatus" "HPA007246: " "unprognostic (6.39e-3)" "potential prognostic favorable (1.24e-4)" "unprognostic (1.48e-3)" "unprognostic (2.80e-1)" "unprognostic (1.35e-1)" "unprognostic (1.99e-3)" "unprognostic (2.41e-1)" "unprognostic (1.51e-1)" "unprognostic (5.68e-2)" "unprognostic (9.34e-3)" "unprognostic (1.29e-1)" ZBP1 "C20orf183, DAI, dJ718J7.3, DLM-1, DLM1" ENSG00000124256 "Z-DNA binding protein 1" Q9H171 20 57603846-57620576 "Predicted intracellular proteins" "Antiviral defense, Apoptosis, Host-virus interaction, Immunity, Innate immunity, Necrosis" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 26.9;lymphoid tissue: 23.5" "Cell type enhanced" "Detected in some" "B-cells: 23.8;Epididymal efferent duct ciliated cells: 13.9;Foveolar cells: 12.5;Neutrophils: 20.1;NK-cells: 46.0;Plasma cells: 180.7;T-cells: 32.7" "Cell type enriched" "Detected in some" 13 "leukocyte: 37.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in all" 8 "Myeloma: 47.0" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Colon - T-cells, Heart muscle - T-cells, Liver - T-cells, Minor Salivary Gland - Plasma cells, Pituitary gland - T-cells, Stomach - Plasma cells, Thyroid gland - T-cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA041256 Enhanced NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 9: Non-specific - Receptor signaling" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 44: Plasma cells - Antibody production & secretion" 8 "HPA041256: " "unprognostic (2.51e-3)" "unprognostic (4.12e-2)" "unprognostic (1.19e-1)" "unprognostic (3.23e-1)" "unprognostic (2.59e-1)" "unprognostic (3.94e-3)" "unprognostic (2.57e-1)" "unprognostic (3.59e-1)" "potential prognostic favorable (2.00e-4)" "potential prognostic unfavorable (1.34e-6)" "unprognostic (3.62e-2)" "unprognostic (3.85e-2)" "unprognostic (1.77e-2)" "unprognostic (8.05e-3)" "unprognostic (1.22e-2)" "unprognostic (8.53e-2)" "unprognostic (1.84e-1)" "unprognostic (1.87e-1)" "unprognostic (1.16e-2)" "unprognostic (2.83e-2)" "unprognostic (1.50e-2)" "unprognostic (5.39e-3)" "unprognostic (1.93e-1)" "unprognostic (1.74e-1)" "potential prognostic favorable (5.42e-4)" "unprognostic (3.42e-2)" "unprognostic (1.60e-1)" "unprognostic (7.89e-2)" "unprognostic (1.14e-1)" "unprognostic (1.90e-1)" ZBTB1 "KIAA0997, ZNF909" ENSG00000126804 "Zinc finger and BTB domain containing 1" Q9Y2K1 14 64503712-64533690 "Predicted intracellular proteins, Transcription factors" "Differentiation, DNA damage, DNA repair, Immunity, Innate immunity, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Innate lymphoid cells: 262.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050516, HPA054552" Approved Supported "Nucleoplasm,Nuclear membrane" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 103: Non-specific - Basic cellular processes" 20 Nucleoplasm "Nuclear membrane" "HPA050516: , HPA054552: " "unprognostic (6.66e-3)" "unprognostic (2.69e-1)" "unprognostic (2.36e-1)" "unprognostic (1.31e-1)" "unprognostic (3.33e-2)" "unprognostic (7.69e-2)" "unprognostic (1.01e-1)" "unprognostic (4.83e-2)" "unprognostic (3.33e-3)" "unprognostic (4.07e-3)" "unprognostic (4.12e-3)" "unprognostic (9.51e-3)" "unprognostic (1.44e-1)" "potential prognostic unfavorable (1.62e-4)" "unprognostic (1.40e-1)" "unprognostic (3.74e-1)" "unprognostic (2.86e-1)" "unprognostic (1.85e-1)" "unprognostic (3.40e-1)" "unprognostic (2.58e-2)" "unprognostic (3.63e-2)" "unprognostic (6.03e-2)" "unprognostic (1.65e-3)" "unprognostic (9.70e-2)" "unprognostic (1.04e-1)" "unprognostic (9.45e-2)" "unprognostic (4.80e-2)" "unprognostic (3.31e-1)" "unprognostic (2.61e-1)" "unprognostic (2.53e-2)" "unprognostic (2.09e-1)" ZBTB10 "FLJ12752, RINZF" ENSG00000205189 "Zinc finger and BTB domain containing 10" Q96DT7 8 80485619-80526265 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "prostate cancer: 50.2" "Skin - Endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021554, HPA050569" Enhanced Enhanced Nucleoplasm NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 60: Prostate cancer - Unknown function" "Cluster 82: Dendritic cells - Antigen presentation" 20 Nucleoplasm "HPA021554: , HPA050569: " "unprognostic (4.66e-2)" "unprognostic (5.26e-3)" "unprognostic (1.30e-1)" "unprognostic (3.14e-1)" "unprognostic (1.05e-1)" "unprognostic (1.65e-1)" "unprognostic (1.23e-1)" "unprognostic (1.46e-2)" "unprognostic (6.82e-2)" "unprognostic (7.87e-2)" "validated prognostic favorable (4.41e-8)" "validated prognostic favorable (3.74e-4)" "unprognostic (1.15e-2)" "unprognostic (6.23e-2)" "unprognostic (1.69e-1)" "unprognostic (2.51e-1)" "potential prognostic unfavorable (3.25e-4)" "unprognostic (3.07e-2)" "unprognostic (1.39e-1)" "unprognostic (3.58e-2)" "unprognostic (7.86e-3)" "unprognostic (7.91e-2)" "potential prognostic unfavorable (4.13e-5)" "unprognostic (1.51e-1)" "unprognostic (5.64e-2)" "unprognostic (1.42e-2)" "unprognostic (3.33e-1)" "potential prognostic unfavorable (2.80e-4)" "unprognostic (2.98e-1)" "unprognostic (1.89e-2)" "unprognostic (8.30e-2)" ZBTB11 "ZNF-U69274, ZNF913" ENSG00000066422 "Zinc finger and BTB domain containing 11" O95625 3 101648889-101677135 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 163.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015328, HPA024138" Approved Enhanced Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 30 Nucleoplasm "HPA015328: , HPA024138: " "unprognostic (6.50e-2)" "unprognostic (1.50e-3)" "unprognostic (3.14e-2)" "unprognostic (1.44e-3)" "unprognostic (4.78e-2)" "unprognostic (2.11e-2)" "unprognostic (1.36e-1)" "unprognostic (8.71e-2)" "unprognostic (3.12e-2)" "unprognostic (7.93e-3)" "potential prognostic favorable (7.56e-6)" "unprognostic (4.82e-2)" "unprognostic (1.38e-1)" "unprognostic (3.60e-3)" "unprognostic (6.22e-2)" "unprognostic (2.89e-1)" "unprognostic (5.08e-2)" "unprognostic (1.40e-1)" "unprognostic (1.70e-1)" "unprognostic (2.48e-2)" "unprognostic (1.78e-3)" "unprognostic (2.30e-2)" "potential prognostic unfavorable (6.32e-4)" "unprognostic (2.81e-3)" "unprognostic (1.51e-3)" "unprognostic (1.50e-1)" "unprognostic (2.05e-2)" "unprognostic (3.53e-1)" "unprognostic (1.54e-1)" "unprognostic (7.78e-3)" "unprognostic (3.30e-1)" ZBTB12 "C6orf46, D6S59E, G10, NG35" ENSG00000204366 "Zinc finger and BTB domain containing 12" Q9Y330 6 31899613-31902086 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "Ovary Serous Cystadenocarcinoma (TCGA): 3.9;Stomach Adenocarcinoma (TCGA): 1.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047161, HPA070639" Approved Enhanced Nucleoplasm NA NA "Cluster 64: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" 3 Nucleoplasm "HPA047161: , HPA070639: " "unprognostic (7.19e-2)" "unprognostic (7.81e-2)" "unprognostic (6.91e-2)" "unprognostic (5.06e-3)" "unprognostic (1.08e-1)" "unprognostic (4.03e-2)" "unprognostic (4.21e-1)" "unprognostic (2.64e-1)" "unprognostic (1.13e-1)" ZBTB14 "ZFP161, ZNF478" ENSG00000198081 "Zinc finger and BTB domain containing 14" O43829 18 5289019-5297053 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050758, HPA070819" Uncertain Supported Nucleoplasm,Nucleoli,Cytosol No No "Cluster 41: Basophils - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 7: Non-specific - Ribosome" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 9: T-cells - Adaptive immunity: Regulation" 62 Nucleoplasm "Nucleoli, Cytosol" "HPA050758: , HPA070819: " "unprognostic (1.22e-1)" "unprognostic (1.96e-1)" "unprognostic (1.22e-1)" "unprognostic (2.00e-1)" "unprognostic (1.87e-2)" "unprognostic (3.34e-1)" "unprognostic (2.55e-2)" "unprognostic (1.08e-2)" "unprognostic (3.92e-2)" "potential prognostic favorable (1.25e-6)" "unprognostic (3.62e-3)" "unprognostic (3.77e-3)" "unprognostic (3.84e-2)" "unprognostic (3.16e-1)" "unprognostic (1.25e-1)" "unprognostic (2.90e-1)" "unprognostic (3.93e-1)" "unprognostic (7.35e-2)" "unprognostic (1.19e-1)" "unprognostic (7.68e-2)" "unprognostic (1.04e-1)" "unprognostic (9.92e-2)" "unprognostic (1.79e-1)" "unprognostic (1.58e-2)" "unprognostic (6.36e-2)" "unprognostic (1.92e-1)" "unprognostic (2.92e-1)" "unprognostic (4.88e-2)" "unprognostic (1.39e-1)" ZBTB16 "PLZF, ZNF145" ENSG00000109906 "Zinc finger and BTB domain containing 16" Q05516 11 114059041-114256765 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Ubl conjugation pathway" "DNA-binding, Repressor" "Cancer-related genes, Disease variant, Intellectual disability, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Myonuclei: 1909.1;Prostatic glandular cells: 1514.9;Proximal tubule cells: 1550.5;Renal collecting duct intercalated cells: 1116.6;Thymic myoid cells: 2005.4" "Cell type enhanced" "Detected in all" "endothelial cell: 807.9" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 25.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 22.5;MAIT T-cell: 37.5;naive B-cell: 10.8;NK-cell: 10.0" "Group enriched" "Detected in many" 5 "B-cells: 10.8;NK-cells: 10.0;T-cells: 37.5" "Group enriched" "Detected in some" 6 "Leukemia: 9.3;prostate cancer: 15.7" "Spleen - Fibroblasts_2, Testis - Endothelial cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001499, CAB004540" Uncertain NA NA "Cluster 24: Non-specific - Transcription" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 53: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 105: Non-specific - Mixed function" 88 "CAB004540: , HPA001499: " "unprognostic (1.68e-2)" "unprognostic (2.71e-1)" "unprognostic (2.01e-1)" "unprognostic (1.40e-2)" "unprognostic (6.96e-2)" "unprognostic (1.85e-1)" "unprognostic (6.71e-2)" "potential prognostic favorable (6.38e-8)" "unprognostic (7.96e-2)" "unprognostic (3.69e-3)" "unprognostic (3.60e-3)" "potential prognostic favorable (1.99e-6)" "unprognostic (1.32e-1)" "unprognostic (2.84e-2)" "unprognostic (7.78e-3)" "unprognostic (1.54e-1)" "potential prognostic unfavorable (6.54e-4)" "unprognostic (6.93e-2)" "unprognostic (5.62e-2)" "unprognostic (1.15e-1)" "unprognostic (6.47e-2)" "unprognostic (7.93e-3)" "unprognostic (1.21e-3)" "unprognostic (2.20e-1)" "unprognostic (9.48e-2)" ZBTB17 "MIZ1, pHZ-67, ZNF151, ZNF60" ENSG00000116809 "Zinc finger and BTB domain containing 17" Q13105 1 15941869-15976132 "Essential proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epicardial cells: 79.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005789 Approved NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 37: Non-specific - mRNA processing" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 23 "HPA005789: " "unprognostic (4.15e-2)" "unprognostic (2.59e-2)" "unprognostic (3.37e-1)" "unprognostic (6.82e-2)" "unprognostic (2.84e-1)" "unprognostic (3.13e-1)" "unprognostic (1.98e-1)" "unprognostic (1.64e-3)" "unprognostic (2.43e-1)" "unprognostic (4.05e-1)" "unprognostic (1.08e-2)" "unprognostic (3.96e-2)" "unprognostic (5.13e-3)" "potential prognostic unfavorable (3.71e-5)" "unprognostic (4.42e-2)" "unprognostic (1.28e-1)" "unprognostic (2.17e-1)" "unprognostic (1.50e-1)" "unprognostic (1.45e-1)" "unprognostic (3.75e-2)" "unprognostic (2.79e-1)" "unprognostic (4.38e-2)" "unprognostic (5.85e-2)" "unprognostic (1.80e-1)" "unprognostic (1.73e-2)" "unprognostic (1.55e-2)" "unprognostic (2.87e-1)" "unprognostic (1.94e-1)" "unprognostic (6.41e-2)" "unprognostic (6.15e-2)" "unprognostic (5.77e-2)" ZBTB18 "C2H2-171, RP58, TAZ-1, ZNF238" ENSG00000179456 "Zinc finger and BTB domain containing 18" Q99592 1 244048547-244057476 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 265.0" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 155.7;Neutrophils: 138.8;pDCs: 160.6" "Cell type enhanced" "Detected in all" "upper rhombic lip: 370.5" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 461.6" "Immune cell enhanced" "Detected in some" "neutrophil: 3.4" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 401.5" "HPA024656, HPA074019" Enhanced Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 27: Cerebellum - Synaptic function" "Cluster 35: Non-specific - DNA binding" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 12 "Nucleoplasm, Nuclear speckles" "HPA024656: , HPA074019: " "unprognostic (4.46e-3)" "unprognostic (6.01e-3)" "unprognostic (4.72e-2)" "unprognostic (1.38e-2)" "unprognostic (1.31e-1)" "unprognostic (3.61e-1)" "potential prognostic favorable (3.29e-4)" "unprognostic (1.05e-1)" "unprognostic (3.51e-1)" "potential prognostic favorable (5.68e-5)" "unprognostic (2.01e-2)" "unprognostic (2.17e-1)" "unprognostic (3.65e-1)" "potential prognostic favorable (3.02e-4)" "unprognostic (2.81e-2)" "unprognostic (3.44e-2)" "unprognostic (1.13e-1)" "unprognostic (1.29e-1)" "unprognostic (3.52e-2)" "unprognostic (3.62e-2)" "unprognostic (1.82e-1)" "unprognostic (5.16e-2)" "unprognostic (4.15e-3)" "unprognostic (3.40e-2)" "unprognostic (1.62e-2)" "unprognostic (2.86e-1)" "unprognostic (3.93e-2)" "unprognostic (2.50e-2)" "unprognostic (1.70e-1)" ZBTB2 "bA351K16.2, KIAA1483, ZNF437" ENSG00000181472 "Zinc finger and BTB domain containing 2" Q8N680 6 151364115-151391559 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 61.4;Endometrial luminal cells: 86.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023136, HPA023137, HPA023458, HPA023487" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 80: Thymus - Adaptive immune response" "Cluster 55: Non-specific - Transcription" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 95 "Nucleoplasm, Cytosol" "HPA023136: , HPA023137: , HPA023458: , HPA023487: " "unprognostic (1.02e-1)" "unprognostic (2.78e-3)" "unprognostic (7.95e-2)" "potential prognostic unfavorable (5.61e-4)" "unprognostic (1.97e-2)" "unprognostic (1.86e-1)" "unprognostic (6.04e-2)" "potential prognostic favorable (7.65e-4)" "unprognostic (3.57e-1)" "unprognostic (5.84e-2)" "unprognostic (3.16e-3)" "unprognostic (1.31e-1)" "potential prognostic unfavorable (3.38e-5)" "potential prognostic unfavorable (1.28e-4)" "unprognostic (3.70e-2)" "unprognostic (2.81e-2)" "unprognostic (1.17e-1)" "unprognostic (8.22e-2)" "unprognostic (1.56e-2)" "unprognostic (4.62e-2)" "unprognostic (5.23e-2)" "unprognostic (4.53e-2)" "unprognostic (1.15e-2)" "unprognostic (4.52e-3)" "unprognostic (3.05e-2)" "unprognostic (1.10e-1)" "unprognostic (2.84e-2)" "unprognostic (2.18e-1)" "unprognostic (4.16e-1)" "unprognostic (3.02e-3)" "unprognostic (5.20e-1)" ZBTB20 "DKFZp566F123, DPZF, ODA-8S, ZNF288" ENSG00000181722 "Zinc finger and BTB domain containing 20" Q9HC78 3 114314500-115147292 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015551, HPA016815" Approved Enhanced "Nucleoplasm,Nuclear bodies" No No "Cluster 32: Basophils - Transcription" "Cluster 22: Epididymis - Mixed function" "Cluster 25: Non-specific - Transcription" "Cluster 65: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" "Nucleoplasm, Nuclear bodies" "HPA015551: , HPA016815: " "potential prognostic favorable (2.83e-4)" "unprognostic (1.99e-1)" "unprognostic (3.65e-1)" "unprognostic (2.14e-1)" "unprognostic (1.68e-1)" "unprognostic (5.67e-2)" "unprognostic (1.00e-1)" "unprognostic (6.11e-2)" "unprognostic (1.42e-1)" "potential prognostic favorable (4.72e-7)" "unprognostic (1.38e-3)" "unprognostic (9.61e-3)" "unprognostic (1.20e-1)" "unprognostic (2.20e-1)" "unprognostic (3.40e-1)" "unprognostic (2.73e-1)" "unprognostic (3.73e-2)" "unprognostic (4.77e-1)" "unprognostic (4.63e-2)" "unprognostic (1.88e-1)" "unprognostic (2.33e-1)" "unprognostic (7.27e-3)" "unprognostic (1.28e-1)" "unprognostic (8.03e-2)" "unprognostic (4.94e-2)" "unprognostic (5.67e-2)" ZBTB21 "KIAA1227, ZNF295" ENSG00000173276 "Zinc finger and BTB domain containing 21" Q9ULJ3 21 41986831-42010387 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 38.9" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024655, HPA031757, HPA031758" Enhanced Enhanced Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 20: Myeloma - Immune response" "Cluster 103: Non-specific - Basic cellular processes" 28 Nucleoplasm "HPA024655: , HPA031757: , HPA031758: " "unprognostic (3.79e-3)" "unprognostic (2.40e-3)" "unprognostic (1.51e-1)" "unprognostic (2.00e-1)" "unprognostic (1.08e-1)" "unprognostic (4.51e-1)" "unprognostic (6.08e-2)" "unprognostic (1.43e-1)" "unprognostic (2.96e-1)" "validated prognostic favorable (1.69e-4)" "validated prognostic favorable (3.53e-4)" "unprognostic (1.64e-1)" "unprognostic (3.23e-2)" "unprognostic (4.15e-2)" "unprognostic (7.90e-2)" "unprognostic (1.88e-1)" "unprognostic (1.58e-2)" "unprognostic (2.27e-2)" "unprognostic (8.05e-3)" "unprognostic (1.36e-1)" "unprognostic (2.37e-2)" "unprognostic (1.70e-2)" "unprognostic (1.01e-2)" "unprognostic (2.71e-2)" "unprognostic (1.27e-1)" "unprognostic (5.40e-2)" "unprognostic (1.77e-1)" "potential prognostic unfavorable (3.69e-4)" "unprognostic (2.38e-1)" ZBTB22 "BING1, fru, fruitless, ZBTB22A, ZNF297, ZNF297A" ENSG00000236104 "Zinc finger and BTB domain containing 22" O15209 6 33314406-33317942 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 3.1;Bergmann glia: 5.4;Brain excitatory neurons: 3.5;Brain inhibitory neurons: 3.4;Choroid plexus epithelial cells: 2.6;Distal convoluted tubule cells: 2.3;Ependymal cells: 9.5;Loop of henle epithelial cells: 2.6;Microglia: 3.8;Oligodendrocyte progenitor cells: 3.6;Oligodendrocytes: 2.8;Other brain neurons: 3.8;Papillary tip epithelial cells: 4.2;Podocytes: 3.6;Proximal tubule cells: 2.5;Renal collecting duct intercalated cells: 2.2;Renal collecting duct principal cells: 3.5;Renal connecting tubule cells: 2.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043848 Approved Nucleoplasm No No "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 53: Neurons - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 98: Neurons - Neurotransmission & signaling" 10 Nucleoplasm "HPA043848: " "unprognostic (2.21e-2)" "unprognostic (2.28e-1)" "unprognostic (3.18e-1)" "potential prognostic unfavorable (2.56e-4)" "unprognostic (6.98e-2)" "unprognostic (1.61e-1)" "unprognostic (2.50e-1)" "unprognostic (3.78e-2)" "unprognostic (1.69e-1)" "unprognostic (1.43e-1)" "unprognostic (1.82e-2)" "unprognostic (9.96e-2)" "unprognostic (1.48e-1)" "unprognostic (8.38e-2)" "unprognostic (2.53e-1)" "unprognostic (2.33e-1)" "unprognostic (3.30e-3)" "unprognostic (2.25e-2)" "unprognostic (3.05e-2)" "unprognostic (2.26e-1)" "unprognostic (8.16e-2)" "unprognostic (1.93e-1)" "unprognostic (2.19e-1)" "unprognostic (1.06e-1)" "unprognostic (1.53e-2)" "unprognostic (3.00e-1)" "unprognostic (1.11e-1)" "unprognostic (1.86e-1)" "unprognostic (2.68e-1)" "unprognostic (2.94e-1)" "unprognostic (9.52e-2)" ZBTB24 "BIF1, KIAA0441, PATZ2, ZNF450" ENSG00000112365 "Zinc finger and BTB domain containing 24" O43167 6 109460632-109483239 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 16.5" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 45.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017872, HPA049003" Uncertain Approved "Nucleoplasm,Cytokinetic bridge,Centrosome" Yes No "Cluster 3: Non-specific - Nuclear processes" "Cluster 40: Non-specific - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 28: Non-specific - Nuclear processes" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 67 Nucleoplasm "Cytokinetic bridge, Centrosome" "HPA017872: , HPA049003: " "unprognostic (2.44e-2)" "unprognostic (3.09e-2)" "unprognostic (1.38e-1)" "unprognostic (2.70e-2)" "unprognostic (8.34e-2)" "unprognostic (2.49e-1)" "unprognostic (1.16e-1)" "unprognostic (7.62e-2)" "unprognostic (2.44e-2)" "unprognostic (3.79e-2)" "unprognostic (2.32e-3)" "unprognostic (1.33e-1)" "potential prognostic unfavorable (4.66e-4)" "potential prognostic unfavorable (7.88e-4)" "unprognostic (1.19e-1)" "unprognostic (1.18e-1)" "unprognostic (2.86e-1)" "unprognostic (1.28e-1)" "unprognostic (3.26e-2)" "unprognostic (5.64e-3)" "unprognostic (2.76e-2)" "unprognostic (1.66e-2)" "unprognostic (1.04e-1)" "unprognostic (7.63e-2)" "unprognostic (2.43e-3)" "unprognostic (7.65e-2)" "unprognostic (9.73e-2)" "unprognostic (1.32e-1)" "unprognostic (3.55e-1)" "unprognostic (2.90e-2)" "unprognostic (2.84e-1)" ZBTB25 "C14orf51, KUP, ZNF46" ENSG00000089775 "Zinc finger and BTB domain containing 25" P24278 14 64449106-64505213 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 210.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054699 Uncertain Enhanced Nucleoplasm NA NA "Cluster 11: T-cells - Unknown function" "Cluster 49: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 9: T-cells - Adaptive immunity: Regulation" 35 Nucleoplasm "HPA054699: " "unprognostic (6.06e-2)" "unprognostic (1.13e-1)" "unprognostic (3.87e-2)" "unprognostic (1.11e-3)" "unprognostic (1.08e-2)" "unprognostic (4.24e-2)" "unprognostic (1.46e-2)" "unprognostic (9.87e-2)" "unprognostic (2.29e-1)" "unprognostic (1.50e-2)" "unprognostic (2.66e-1)" "unprognostic (1.33e-2)" "unprognostic (1.13e-1)" "potential prognostic unfavorable (8.71e-5)" "unprognostic (1.60e-1)" "unprognostic (1.58e-1)" "unprognostic (2.75e-2)" "unprognostic (2.01e-1)" "unprognostic (2.72e-1)" "unprognostic (2.52e-1)" "unprognostic (9.95e-2)" "unprognostic (3.18e-1)" "unprognostic (1.18e-1)" "unprognostic (3.06e-1)" "unprognostic (7.13e-2)" "unprognostic (8.83e-3)" "unprognostic (5.49e-2)" "unprognostic (1.07e-1)" "unprognostic (1.14e-1)" "potential prognostic unfavorable (3.41e-4)" "unprognostic (3.33e-2)" ZBTB26 ZNF481 ENSG00000171448 "Zinc finger and BTB domain containing 26" Q9HCK0 9 122915566-122931512 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 104.8;Sertoli cells: 43.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021444 Uncertain NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 27 "HPA021444: " "unprognostic (4.54e-3)" "unprognostic (3.19e-3)" "unprognostic (1.96e-2)" "unprognostic (2.04e-2)" "unprognostic (1.99e-2)" "unprognostic (1.22e-1)" "unprognostic (8.61e-2)" "unprognostic (2.37e-1)" "unprognostic (1.13e-1)" "unprognostic (1.19e-1)" "validated prognostic favorable (5.43e-4)" "validated prognostic favorable (5.32e-4)" "unprognostic (1.72e-1)" "unprognostic (2.88e-3)" "unprognostic (3.66e-1)" "unprognostic (4.29e-2)" "unprognostic (1.56e-2)" "unprognostic (1.76e-1)" "unprognostic (4.28e-3)" "unprognostic (3.85e-2)" "unprognostic (2.17e-1)" "unprognostic (3.17e-1)" "unprognostic (4.85e-3)" "unprognostic (2.16e-1)" "potential prognostic favorable (1.09e-4)" "unprognostic (4.60e-2)" "unprognostic (7.46e-2)" "unprognostic (2.13e-1)" "unprognostic (1.68e-1)" "unprognostic (1.54e-1)" "unprognostic (1.14e-1)" ZBTB3 FLJ23392 ENSG00000185670 "Zinc finger and BTB domain containing 3" Q9H5J0 11 62748319-62754184 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 15.6;Late spermatids: 17.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035321, HPA035322" Approved Approved Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 40: Non-specific - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 24: Non-specific - Unknown function" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 9 Mitochondria "HPA035321: , HPA035322: " "unprognostic (3.13e-2)" "unprognostic (6.79e-3)" "unprognostic (8.25e-2)" "unprognostic (8.43e-3)" "unprognostic (1.57e-1)" "unprognostic (6.82e-2)" "unprognostic (1.51e-1)" "unprognostic (2.24e-2)" "unprognostic (3.87e-2)" "unprognostic (4.59e-3)" "unprognostic (6.04e-2)" "unprognostic (6.24e-3)" "potential prognostic favorable (2.26e-4)" "unprognostic (3.84e-2)" "unprognostic (1.23e-2)" "unprognostic (7.65e-2)" "unprognostic (3.74e-1)" "unprognostic (1.17e-2)" "unprognostic (1.69e-1)" "unprognostic (3.34e-1)" "unprognostic (1.98e-1)" "unprognostic (4.28e-1)" "unprognostic (1.72e-1)" "unprognostic (1.95e-1)" "unprognostic (7.85e-3)" "unprognostic (1.26e-1)" "unprognostic (2.94e-1)" "potential prognostic favorable (3.35e-4)" "unprognostic (2.21e-2)" "unprognostic (1.21e-1)" "unprognostic (1.68e-1)" ZBTB32 "FAXF, FAZF, Rog, TZFP, ZNF538" ENSG00000011590 "Zinc finger and BTB domain containing 32" Q9Y2Y4 19 35704558-35717038 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "testis: 47.0" "Group enriched" "Detected in many" 5 "Late primary spermatocytes: 211.7;Late spermatids: 109.5" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 10.5" "Lineage enriched" "Detected in many" 5 "B-cells: 10.5" "Group enriched" "Detected in some" 4 "lymphoma: 10.1;Myeloma: 3.8" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA076730 Enhanced NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 79: Testis - Spermatogenesis" "Cluster 15: Non-specific - Transcription" "Cluster 55: Lymphoma - Immune response" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 10 "HPA076730: " "unprognostic (2.12e-2)" "unprognostic (3.83e-1)" "unprognostic (4.30e-2)" ZBTB33 "kaiso, WUGSC:H_DJ525N14.1, ZNF-kaiso, ZNF348" ENSG00000177485 "Zinc finger and BTB domain containing 33" Q86T24 X 120250752-120258398 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000755, CAB001980, HPA005732" Approved Enhanced "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 36: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 28 "Nucleoplasm, Plasma membrane, Cytosol" "CAB001980: , HPA000755: , HPA005732: " "unprognostic (2.44e-1)" "unprognostic (8.55e-3)" "unprognostic (1.19e-1)" "unprognostic (1.82e-1)" "unprognostic (3.64e-1)" "unprognostic (3.01e-1)" "unprognostic (2.90e-2)" "unprognostic (1.79e-2)" "unprognostic (7.64e-2)" "unprognostic (1.55e-3)" "potential prognostic favorable (2.84e-5)" "unprognostic (4.56e-2)" "unprognostic (7.22e-2)" "unprognostic (9.84e-2)" "unprognostic (4.08e-1)" "unprognostic (1.64e-1)" "unprognostic (1.23e-2)" "unprognostic (1.71e-1)" "unprognostic (1.52e-1)" "unprognostic (4.82e-1)" "unprognostic (8.27e-2)" "unprognostic (1.89e-1)" "unprognostic (8.11e-2)" "unprognostic (7.08e-2)" "unprognostic (3.37e-2)" "unprognostic (3.20e-1)" "unprognostic (1.42e-2)" "unprognostic (1.55e-1)" "unprognostic (2.20e-1)" "unprognostic (3.04e-2)" "unprognostic (6.64e-2)" ZBTB34 "KIAA1993, MGC24652, ZNF918" ENSG00000177125 "Zinc finger and BTB domain containing 34" 9 126860639-126885878 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 41.0;Neutrophil progenitors: 35.7;Neutrophils: 63.9;Platelets: 52.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023893 Approved Supported Nucleoplasm NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 40: Non-specific - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 24: Neutrophils - Innate immunity signal integration" 2 Nucleoplasm "HPA023893: " "unprognostic (1.47e-2)" "unprognostic (2.58e-2)" "unprognostic (2.52e-1)" "unprognostic (9.42e-2)" "unprognostic (4.67e-3)" "unprognostic (2.13e-3)" "unprognostic (1.59e-1)" "unprognostic (4.63e-3)" "unprognostic (1.02e-1)" "unprognostic (4.65e-2)" "potential prognostic favorable (2.34e-5)" "unprognostic (1.16e-3)" "unprognostic (1.71e-1)" "potential prognostic unfavorable (2.02e-4)" "unprognostic (3.10e-2)" "unprognostic (3.32e-1)" "unprognostic (1.68e-1)" "unprognostic (2.97e-1)" "unprognostic (3.43e-3)" "unprognostic (5.48e-2)" "unprognostic (8.32e-2)" "unprognostic (1.36e-1)" "unprognostic (1.60e-1)" "unprognostic (2.30e-3)" "unprognostic (3.99e-2)" "unprognostic (1.59e-1)" "unprognostic (5.34e-2)" "unprognostic (8.69e-2)" "unprognostic (2.15e-1)" "unprognostic (8.53e-2)" "unprognostic (2.11e-1)" ZBTB37 "MGC2629, ZNF908" ENSG00000185278 "Zinc finger and BTB domain containing 37" Q5TC79 1 173868082-173903547 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bergmann glia: 82.7;Late spermatids: 90.7;Neutrophils: 89.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023438 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 48: Neutrophils - Phagocytosis & degranulation" "Nucleoplasm, Nucleoli fibrillar center" Cytosol "HPA023438: " "unprognostic (2.27e-1)" "unprognostic (1.82e-1)" "unprognostic (1.68e-1)" "unprognostic (6.64e-2)" "unprognostic (3.29e-1)" "unprognostic (1.35e-1)" "unprognostic (4.12e-3)" "unprognostic (2.38e-2)" "unprognostic (4.42e-2)" "unprognostic (9.26e-3)" "unprognostic (7.61e-2)" "unprognostic (1.21e-1)" "unprognostic (2.32e-3)" "unprognostic (2.28e-1)" "unprognostic (1.12e-1)" "unprognostic (1.59e-1)" "unprognostic (4.38e-2)" "unprognostic (5.43e-2)" "unprognostic (4.52e-2)" "unprognostic (3.46e-2)" "unprognostic (1.09e-1)" "unprognostic (6.25e-2)" "unprognostic (4.57e-2)" "unprognostic (2.14e-1)" "unprognostic (1.59e-1)" "unprognostic (7.60e-3)" "unprognostic (1.21e-1)" ZBTB38 "CIBZ, FLJ35036, PPP1R171, ZNF921" ENSG00000177311 "Zinc finger and BTB domain containing 38" Q8NAP3 3 141324213-141449792 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Myeloma: 324.3" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014865, HPA059378" Enhanced Nucleoplasm No No "Cluster 43: Non-specific - Transcription & Translation" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 34: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 44: Plasma cells - Antibody production & secretion" 8 Nucleoplasm "HPA014865: , HPA059378: " "unprognostic (1.77e-2)" "unprognostic (9.25e-2)" "unprognostic (1.71e-1)" "unprognostic (5.41e-2)" "unprognostic (2.62e-2)" "unprognostic (4.78e-2)" "unprognostic (4.19e-1)" "unprognostic (5.81e-2)" "unprognostic (6.65e-2)" "unprognostic (5.19e-3)" "potential prognostic favorable (5.13e-5)" "unprognostic (1.99e-1)" "unprognostic (1.62e-2)" "unprognostic (9.88e-2)" "unprognostic (2.10e-1)" "unprognostic (6.00e-2)" "unprognostic (5.36e-2)" "unprognostic (2.14e-1)" "unprognostic (2.08e-2)" "unprognostic (6.48e-2)" "unprognostic (9.24e-3)" "unprognostic (3.79e-3)" "unprognostic (1.25e-1)" "unprognostic (2.97e-1)" "unprognostic (2.14e-2)" "unprognostic (4.79e-2)" "unprognostic (2.65e-1)" "unprognostic (2.25e-2)" "unprognostic (1.14e-1)" "unprognostic (8.64e-3)" "unprognostic (2.10e-1)" ZBTB39 "KIAA0352, ZNF922" ENSG00000166860 "Zinc finger and BTB domain containing 39" O15060 12 56998836-57006546 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 20.8;Early primary spermatocytes: 15.5;Early spermatids: 29.8;Late spermatids: 31.4;Retinal horizontal cells: 16.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 14.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016866, HPA020306" Uncertain Approved Vesicles NA NA "Cluster 32: Basophils - Transcription" "Cluster 39: Testis - Nuclear processes" "Cluster 6: Non-specific - Immune response" "Cluster 38: Non-specific - Transcription" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 9 Vesicles "HPA016866: , HPA020306: " "unprognostic (2.62e-1)" "unprognostic (1.67e-2)" "unprognostic (4.13e-1)" "unprognostic (1.28e-2)" "unprognostic (3.41e-1)" "unprognostic (7.90e-2)" "unprognostic (1.03e-1)" "unprognostic (2.45e-3)" "unprognostic (1.42e-2)" "unprognostic (1.93e-1)" "potential prognostic favorable (4.85e-5)" "unprognostic (7.95e-2)" "unprognostic (3.25e-1)" "unprognostic (4.40e-3)" "unprognostic (3.01e-1)" "unprognostic (4.07e-1)" "unprognostic (1.08e-1)" "unprognostic (6.63e-2)" "unprognostic (4.68e-3)" "unprognostic (9.16e-2)" "unprognostic (2.29e-1)" "unprognostic (3.86e-2)" "unprognostic (1.56e-1)" "unprognostic (1.34e-1)" "unprognostic (1.45e-2)" "unprognostic (9.26e-2)" "unprognostic (2.24e-2)" "unprognostic (2.99e-1)" "unprognostic (2.88e-1)" "unprognostic (1.57e-1)" "unprognostic (7.45e-2)" ZBTB4 "KAISO-L1, KIAA1538, ZNF903" ENSG00000174282 "Zinc finger and BTB domain containing 4" Q9P1Z0 17 7459366-7484263 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 56.9;Bergmann glia: 50.9;Brain excitatory neurons: 49.5;Brain inhibitory neurons: 48.1;Choroid plexus epithelial cells: 111.6;Distal convoluted tubule cells: 50.7;Ependymal cells: 37.5;Loop of henle epithelial cells: 56.9;Microglia: 36.9;Oligodendrocyte progenitor cells: 31.3;Oligodendrocytes: 38.6;Other brain neurons: 49.2;Papillary tip epithelial cells: 40.9;Podocytes: 94.2;Proximal tubule cells: 40.1;Renal collecting duct intercalated cells: 84.3;Renal collecting duct principal cells: 59.2;Renal connecting tubule cells: 57.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008980, HPA064763" Supported Supported "Nucleoplasm,Nuclear bodies,Cytosol" No No "Cluster 3: Non-specific - Nuclear processes" "Cluster 74: Non-specific - Signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 42: Non-specific - Unknown function" "Cluster 102: Non-specific - Mixed function" 11 "Nuclear bodies" "Nucleoplasm, Cytosol" "CAB008980: , HPA064763: " "unprognostic (2.99e-3)" "unprognostic (4.96e-1)" "unprognostic (1.86e-1)" "unprognostic (1.10e-3)" "unprognostic (1.95e-1)" "unprognostic (2.58e-2)" "unprognostic (6.40e-2)" "unprognostic (2.95e-1)" "unprognostic (3.78e-3)" "unprognostic (1.30e-1)" "validated prognostic favorable (6.23e-9)" "validated prognostic favorable (2.84e-4)" "unprognostic (1.42e-2)" "unprognostic (4.74e-1)" "unprognostic (1.83e-3)" "potential prognostic favorable (2.19e-4)" "unprognostic (3.16e-3)" "unprognostic (1.07e-2)" "unprognostic (9.91e-2)" "potential prognostic unfavorable (6.32e-4)" "unprognostic (3.29e-2)" "unprognostic (5.42e-3)" "unprognostic (5.57e-2)" "unprognostic (1.05e-1)" "unprognostic (5.02e-2)" "unprognostic (4.31e-2)" "unprognostic (2.62e-2)" "unprognostic (1.88e-1)" "unprognostic (1.10e-1)" "unprognostic (1.72e-1)" "unprognostic (1.06e-1)" ZBTB40 "KIAA0478, ZNF923" ENSG00000184677 "Zinc finger and BTB domain containing 40" Q9NUA8 1 22428838-22531157 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042386 Approved Nucleoplasm NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 49: Non-specific - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 2 Nucleoplasm "HPA042386: " "unprognostic (5.60e-2)" "unprognostic (1.69e-1)" "unprognostic (2.05e-1)" "unprognostic (1.30e-1)" "unprognostic (1.11e-1)" "unprognostic (1.09e-1)" "unprognostic (1.41e-1)" "unprognostic (3.67e-3)" "unprognostic (2.31e-3)" "unprognostic (4.81e-3)" "validated prognostic favorable (1.39e-6)" "validated prognostic favorable (2.36e-4)" "unprognostic (1.41e-2)" "potential prognostic unfavorable (1.71e-8)" "unprognostic (1.83e-1)" "unprognostic (3.01e-2)" "unprognostic (1.96e-1)" "unprognostic (1.52e-1)" "unprognostic (1.66e-2)" "unprognostic (4.80e-2)" "unprognostic (8.43e-2)" "unprognostic (2.36e-3)" "unprognostic (6.14e-2)" "unprognostic (2.98e-1)" "unprognostic (6.74e-2)" "potential prognostic favorable (3.18e-4)" "unprognostic (3.50e-2)" "unprognostic (1.21e-1)" "unprognostic (3.03e-1)" "unprognostic (4.62e-2)" "unprognostic (1.05e-1)" ZBTB41 "DKFZp686C06120, FLJ36199, FRBZ1, ZNF924" ENSG00000177888 "Zinc finger and BTB domain containing 41" Q5SVQ8 1 197153682-197201293 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Corticotrophs: 92.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034841, HPA034842" Uncertain Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 7: Liver cancer - Metabolism" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 4 "Nuclear membrane" "Nucleoplasm, Cytosol" "HPA034841: , HPA034842: " "unprognostic (3.29e-1)" "unprognostic (1.55e-1)" "unprognostic (1.73e-1)" "unprognostic (9.60e-3)" "unprognostic (1.37e-1)" "unprognostic (1.80e-2)" "unprognostic (1.10e-1)" "unprognostic (3.81e-1)" "unprognostic (5.25e-2)" "unprognostic (1.53e-1)" "potential prognostic favorable (5.64e-5)" "unprognostic (2.34e-1)" "unprognostic (7.79e-3)" "potential prognostic unfavorable (4.27e-4)" "unprognostic (7.00e-2)" "unprognostic (1.12e-1)" "unprognostic (5.08e-2)" "unprognostic (6.39e-2)" "unprognostic (3.25e-1)" "unprognostic (1.39e-1)" "unprognostic (4.94e-3)" "unprognostic (5.19e-3)" "unprognostic (8.55e-2)" "unprognostic (9.55e-2)" "unprognostic (2.22e-2)" "unprognostic (1.43e-1)" "unprognostic (3.24e-2)" "unprognostic (2.47e-1)" "unprognostic (2.29e-1)" "unprognostic (4.59e-3)" "unprognostic (1.38e-1)" ZBTB42 ZNF925 ENSG00000179627 "Zinc finger and BTB domain containing 42" B2RXF5 14 104800596-104804712 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 15.2;Fallopian tube ciliated cells: 18.3" "Cell type enhanced" "Detected in some" "endothelial cell: 1.4;ependymal cell: 1.7;leukocyte: 1.5;vascular associated smooth muscle cell: 2.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 10 "eosinophil: 5.4" "Lineage enriched" "Detected in single" 10 "granulocytes: 5.4" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Breast - Breast glandular cells, Prostate - Prostate glandular cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA066961 Approved Supported Nucleoplasm NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 60: Stomach - Digestion" "Cluster 43: Hindbrain - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 81: Alveolar cells - Lung function" 43 Nucleoplasm "HPA066961: " "unprognostic (1.06e-1)" "unprognostic (1.68e-1)" "unprognostic (1.52e-1)" "unprognostic (2.25e-1)" "unprognostic (1.03e-1)" "unprognostic (3.48e-2)" "unprognostic (1.92e-1)" "unprognostic (1.22e-2)" "unprognostic (1.62e-1)" "unprognostic (2.78e-2)" "potential prognostic favorable (9.15e-6)" "unprognostic (2.38e-3)" "unprognostic (4.88e-2)" "unprognostic (1.55e-2)" "unprognostic (3.66e-1)" "unprognostic (6.30e-2)" "unprognostic (1.16e-1)" "unprognostic (2.09e-2)" "unprognostic (4.19e-2)" "unprognostic (2.01e-1)" "unprognostic (4.36e-2)" "unprognostic (1.27e-1)" "unprognostic (2.48e-1)" "unprognostic (2.71e-1)" "unprognostic (2.50e-1)" "potential prognostic unfavorable (9.84e-4)" "unprognostic (8.83e-2)" "unprognostic (4.63e-1)" "unprognostic (9.03e-2)" "unprognostic (4.70e-2)" "unprognostic (1.32e-1)" ZBTB43 "FLJ22470, KIAA0414, ZBTB22B, ZNF-X, ZNF297B" ENSG00000169155 "Zinc finger and BTB domain containing 43" O43298 9 126805006-126838210 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 57.4" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 246.8;Ocular epithelial cells: 226.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016825 Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 27 "Nucleoplasm, Nucleoli" "HPA016825: " "unprognostic (6.59e-2)" "unprognostic (2.05e-2)" "unprognostic (3.31e-1)" "unprognostic (1.26e-1)" "unprognostic (1.20e-3)" "unprognostic (5.75e-2)" "unprognostic (1.19e-1)" "unprognostic (2.01e-2)" "unprognostic (5.05e-1)" "unprognostic (2.87e-1)" "unprognostic (6.21e-3)" "potential prognostic favorable (7.32e-5)" "unprognostic (5.74e-2)" "unprognostic (6.39e-2)" "unprognostic (2.75e-3)" "unprognostic (8.80e-2)" "unprognostic (6.06e-2)" "unprognostic (1.76e-1)" "unprognostic (1.63e-1)" "unprognostic (7.25e-2)" "unprognostic (9.69e-2)" "unprognostic (1.89e-1)" "potential prognostic unfavorable (8.52e-4)" "potential prognostic unfavorable (4.02e-4)" "unprognostic (4.34e-3)" "potential prognostic favorable (4.84e-4)" "unprognostic (1.03e-1)" "unprognostic (1.97e-1)" "unprognostic (3.01e-2)" "unprognostic (1.53e-1)" "unprognostic (5.09e-2)" ZBTB44 "BTBD15, HSPC063, ZNF851" ENSG00000196323 "Zinc finger and BTB domain containing 44" Q8NCP5 11 130226677-130314917 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052589 Approved Approved Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 51: Secretory epithelial cells - Mixed function" 7 Nucleoplasm "HPA052589: " "unprognostic (1.33e-1)" "unprognostic (2.43e-1)" "unprognostic (1.91e-1)" "unprognostic (4.63e-1)" "unprognostic (1.64e-1)" "unprognostic (4.10e-2)" "unprognostic (1.54e-1)" "unprognostic (2.53e-3)" "unprognostic (2.32e-1)" "unprognostic (2.24e-1)" "validated prognostic favorable (3.25e-8)" "validated prognostic favorable (3.25e-4)" "unprognostic (3.38e-1)" "unprognostic (7.33e-2)" "unprognostic (1.21e-1)" "unprognostic (6.38e-2)" "unprognostic (2.44e-1)" "unprognostic (4.96e-1)" "unprognostic (1.24e-1)" "unprognostic (1.88e-1)" "unprognostic (2.03e-1)" "unprognostic (5.85e-3)" "unprognostic (7.28e-2)" "unprognostic (1.37e-1)" "potential prognostic favorable (3.31e-4)" "unprognostic (3.35e-2)" "unprognostic (2.69e-2)" "unprognostic (1.08e-1)" "unprognostic (4.43e-1)" "unprognostic (1.21e-1)" "unprognostic (2.96e-2)" ZBTB45 "FLJ14486, ZNF499" ENSG00000119574 "Zinc finger and BTB domain containing 45" Q96K62 19 58513530-58538911 "Predicted intracellular proteins, Transcription factors" "Neurogenesis, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 32.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "prostate cancer: 76.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035754, HPA075485" Uncertain Uncertain "Nuclear bodies,Cytosol" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 3: Early primary spermatocytes - Early meiosis" 1 Cytosol "Nuclear bodies" "HPA035754: , HPA075485: " "unprognostic (9.11e-3)" "unprognostic (1.03e-1)" "unprognostic (4.75e-2)" "unprognostic (6.57e-3)" "unprognostic (2.44e-1)" "unprognostic (8.78e-2)" "unprognostic (1.28e-1)" "unprognostic (1.05e-1)" "unprognostic (5.68e-2)" "unprognostic (1.44e-1)" "unprognostic (1.98e-3)" "unprognostic (3.59e-1)" "unprognostic (5.95e-3)" "unprognostic (6.24e-3)" "unprognostic (1.09e-1)" "unprognostic (5.77e-2)" "unprognostic (1.71e-1)" "unprognostic (6.98e-2)" "unprognostic (1.31e-2)" "unprognostic (2.23e-1)" "unprognostic (8.07e-3)" "unprognostic (5.32e-2)" "unprognostic (1.26e-2)" "potential prognostic unfavorable (2.76e-4)" "unprognostic (1.33e-1)" "unprognostic (1.32e-2)" "unprognostic (2.86e-1)" "unprognostic (1.21e-1)" "unprognostic (7.65e-2)" "unprognostic (9.34e-3)" "unprognostic (3.62e-3)" ZBTB46 "BTBD4, BZEL, FLJ13502, RINZF, ZNF340" ENSG00000130584 "Zinc finger and BTB domain containing 46" Q86UZ6 20 63743668-63832038 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 24.1" "Cell type enhanced" "Detected in many" "cDC: 168.1;Choroid plexus epithelial cells: 128.6;Lymphatic endothelial cells: 121.5;Pericytes: 127.4;Podocytes: 261.7;Vascular endothelial cells: 140.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Liver - Hepatic stellate cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013997, HPA048051" Uncertain Approved Nucleoplasm NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 64: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 1 Nucleoplasm "HPA013997: , HPA048051: " "unprognostic (2.24e-2)" "unprognostic (2.09e-2)" "potential prognostic favorable (1.02e-4)" "unprognostic (7.06e-2)" "unprognostic (4.28e-2)" "unprognostic (1.89e-1)" "unprognostic (1.50e-1)" "unprognostic (2.49e-3)" "unprognostic (1.08e-1)" "unprognostic (6.11e-2)" "validated prognostic favorable (8.33e-4)" "validated prognostic favorable (4.34e-4)" "unprognostic (3.62e-2)" "unprognostic (6.11e-2)" "unprognostic (1.26e-1)" "unprognostic (6.20e-2)" "unprognostic (7.98e-2)" "unprognostic (1.58e-2)" "unprognostic (1.91e-1)" "unprognostic (9.38e-2)" "unprognostic (1.27e-1)" "potential prognostic favorable (3.00e-4)" "unprognostic (3.34e-3)" "unprognostic (2.02e-1)" "unprognostic (1.23e-1)" "unprognostic (1.41e-1)" "unprognostic (1.89e-1)" "unprognostic (2.40e-1)" "unprognostic (1.00e-1)" "unprognostic (1.94e-1)" "unprognostic (2.93e-1)" ZBTB47 "DKFZp434N0615, KIAA1190, ZNF651" ENSG00000114853 "Zinc finger and BTB domain containing 47" Q9UFB7 3 42653697-42667580 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 99.1" "Cell type enhanced" "Detected in many" "Astrocytes: 28.5;Cardiomyocytes: 51.8;Thymic myoid cells: 31.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Minor Salivary Gland - Endothelial cells, Skin - Fibroblasts_2, Spleen - Fibroblasts_1, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074057 Enhanced Approved Nucleoplasm NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 8 Nucleoplasm "HPA074057: " "unprognostic (5.59e-3)" "unprognostic (6.76e-2)" "unprognostic (3.64e-2)" "potential prognostic unfavorable (6.36e-5)" "unprognostic (3.02e-1)" "unprognostic (4.74e-1)" "unprognostic (5.71e-2)" "unprognostic (8.16e-3)" "unprognostic (2.32e-2)" "unprognostic (5.63e-2)" "unprognostic (2.27e-2)" "unprognostic (2.67e-1)" "unprognostic (2.10e-2)" "unprognostic (2.40e-1)" "unprognostic (1.58e-2)" "unprognostic (8.51e-2)" "unprognostic (3.99e-2)" "unprognostic (7.45e-2)" "unprognostic (7.81e-2)" "unprognostic (9.98e-3)" "unprognostic (2.35e-2)" "unprognostic (8.78e-2)" "unprognostic (2.89e-1)" "unprognostic (1.63e-1)" "unprognostic (5.52e-2)" "potential prognostic favorable (4.06e-4)" "unprognostic (4.36e-2)" "unprognostic (1.63e-2)" "unprognostic (1.33e-1)" "unprognostic (5.34e-2)" "unprognostic (1.81e-1)" ZBTB48 "HKR3, TZAP, ZNF855" ENSG00000204859 "Zinc finger and BTB domain containing 48" P10074 1 6579994-6589280 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 74.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030417 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 47: Testis - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 37: Non-specific - mRNA processing" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" 31 Nucleoplasm Cytosol "HPA030417: " "unprognostic (2.99e-1)" "unprognostic (9.72e-2)" "unprognostic (7.62e-3)" "unprognostic (9.07e-2)" "unprognostic (1.45e-1)" "unprognostic (8.08e-2)" "unprognostic (1.84e-1)" "potential prognostic favorable (5.11e-4)" "unprognostic (3.14e-1)" "unprognostic (1.96e-1)" "potential prognostic favorable (2.24e-5)" "unprognostic (1.43e-3)" "unprognostic (1.67e-1)" "unprognostic (1.79e-2)" "unprognostic (2.95e-1)" "unprognostic (5.14e-3)" "unprognostic (2.10e-1)" "unprognostic (3.20e-1)" "unprognostic (3.80e-1)" "unprognostic (6.37e-2)" "unprognostic (1.39e-2)" "unprognostic (1.37e-3)" "unprognostic (1.46e-1)" "unprognostic (1.49e-1)" "unprognostic (2.96e-2)" "unprognostic (1.28e-3)" "unprognostic (9.85e-2)" "unprognostic (4.12e-1)" "unprognostic (1.11e-1)" "unprognostic (1.42e-1)" "unprognostic (3.16e-2)" ZBTB49 "FLJ38559, ZNF509" ENSG00000168826 "Zinc finger and BTB domain containing 49" Q6ZSB9 4 4290251-4321786 "Predicted intracellular proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 33.1;Corticotrophs: 32.1;Myonuclei: 34.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pituitary gland - Corticotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024450 Approved Approved Nucleoplasm,Microtubules,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 40: Non-specific - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 55: Myocytes - Oxidative muscle function" 19 Nucleoplasm "Microtubules, Cytosol" "HPA024450: " "unprognostic (1.64e-1)" "unprognostic (2.30e-1)" "unprognostic (1.23e-1)" "unprognostic (2.79e-2)" "unprognostic (1.82e-1)" "unprognostic (6.02e-2)" "unprognostic (6.13e-2)" "unprognostic (7.46e-3)" "potential prognostic favorable (2.04e-4)" "unprognostic (1.34e-2)" "potential prognostic favorable (6.59e-4)" "unprognostic (1.30e-2)" "unprognostic (7.54e-2)" "unprognostic (2.72e-1)" "unprognostic (2.42e-1)" "unprognostic (2.43e-1)" "unprognostic (7.61e-2)" "unprognostic (2.67e-1)" "unprognostic (5.58e-2)" "unprognostic (2.56e-2)" "unprognostic (7.75e-3)" "unprognostic (4.63e-3)" "unprognostic (4.21e-2)" "unprognostic (1.35e-2)" "unprognostic (1.29e-1)" "unprognostic (3.71e-2)" "unprognostic (3.23e-1)" "unprognostic (2.31e-1)" "unprognostic (1.21e-1)" "unprognostic (9.39e-2)" ZBTB5 KIAA0354 ENSG00000168795 "Zinc finger and BTB domain containing 5" O15062 9 37438102-37465450 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 68.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021521 Approved Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 65: Non-specific - Cell growth & division" 13 "Nucleoplasm, Nuclear bodies" "Golgi apparatus" "HPA021521: " "unprognostic (1.68e-2)" "unprognostic (4.64e-2)" "unprognostic (2.06e-1)" "unprognostic (2.50e-1)" "unprognostic (3.08e-1)" "unprognostic (5.79e-2)" "unprognostic (1.24e-2)" "potential prognostic favorable (1.88e-4)" "unprognostic (7.28e-3)" "unprognostic (2.17e-1)" "validated prognostic favorable (1.40e-6)" "validated prognostic favorable (1.22e-4)" "unprognostic (8.73e-3)" "unprognostic (3.54e-3)" "unprognostic (7.85e-2)" "unprognostic (1.62e-2)" "unprognostic (1.91e-2)" "unprognostic (2.05e-1)" "unprognostic (3.51e-2)" "unprognostic (2.20e-1)" "unprognostic (2.26e-1)" "unprognostic (6.79e-2)" "unprognostic (2.38e-2)" "unprognostic (2.70e-2)" "unprognostic (1.49e-3)" "unprognostic (7.06e-2)" "unprognostic (1.53e-2)" "unprognostic (5.01e-2)" "unprognostic (1.70e-1)" "unprognostic (1.20e-3)" "unprognostic (3.34e-2)" ZBTB6 "ZID, ZNF482" ENSG00000186130 "Zinc finger and BTB domain containing 6" Q15916 9 122908056-122913323 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 10.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054111, HPA076894" Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 55: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 17: Non-specific - RNA processing" 7 Nucleoplasm Mitochondria "HPA054111: , HPA076894: " "unprognostic (2.32e-2)" "unprognostic (1.79e-2)" "unprognostic (2.32e-1)" "unprognostic (1.01e-1)" "unprognostic (2.16e-1)" "potential prognostic unfavorable (8.74e-4)" "unprognostic (6.48e-3)" "unprognostic (1.16e-1)" "unprognostic (2.91e-1)" "unprognostic (2.95e-2)" "potential prognostic favorable (3.45e-6)" "unprognostic (1.37e-2)" "unprognostic (1.47e-1)" "unprognostic (1.15e-2)" "unprognostic (1.45e-1)" "unprognostic (1.38e-1)" "unprognostic (1.69e-1)" "unprognostic (1.98e-1)" "unprognostic (3.75e-2)" "unprognostic (8.20e-2)" "potential prognostic unfavorable (1.23e-4)" "unprognostic (1.89e-1)" "unprognostic (1.47e-1)" "unprognostic (9.01e-2)" "unprognostic (5.35e-3)" "unprognostic (5.47e-3)" "unprognostic (1.29e-1)" "unprognostic (1.03e-1)" "unprognostic (2.30e-1)" "unprognostic (3.12e-2)" "unprognostic (1.54e-3)" ZBTB7A "DKFZp547O146, FBI-1, LRF, pokemon, ZBTB7, ZNF857A" ENSG00000178951 "Zinc finger and BTB domain containing 7A" O95365 19 4043303-4066899 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037214, CAB037285, HPA046387" Supported Approved Nucleoplasm NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 23: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 33 Nucleoplasm "CAB037214: , CAB037285: , HPA046387: " "unprognostic (8.16e-3)" "unprognostic (1.23e-1)" "potential prognostic favorable (5.61e-4)" "unprognostic (1.10e-3)" "unprognostic (2.94e-1)" "unprognostic (3.60e-1)" "unprognostic (3.17e-1)" "unprognostic (6.99e-2)" "unprognostic (5.25e-3)" "unprognostic (1.68e-1)" "potential prognostic favorable (1.56e-4)" "unprognostic (1.13e-2)" "unprognostic (2.04e-2)" "unprognostic (2.43e-2)" "unprognostic (1.35e-2)" "unprognostic (9.61e-2)" "unprognostic (1.97e-1)" "unprognostic (1.76e-1)" "unprognostic (1.98e-1)" "unprognostic (3.79e-3)" "unprognostic (1.96e-2)" "unprognostic (4.44e-3)" "unprognostic (1.02e-1)" "unprognostic (1.04e-1)" "unprognostic (1.28e-1)" "unprognostic (1.64e-2)" "unprognostic (3.01e-1)" "potential prognostic favorable (7.09e-4)" "unprognostic (2.16e-1)" "unprognostic (4.62e-2)" "unprognostic (5.39e-3)" ZBTB7B "c-Krox, hcKrox, ZBTB15, ZFP67, ZNF857B" ENSG00000160685 "Zinc finger and BTB domain containing 7B" O15156 1 155002630-155018523 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 86.6;Colonocytes: 110.3;Enterocytes: 172.4;Esophageal apical cells: 152.4;Esophageal suprabasal cells: 104.8;Neutrophils: 77.7" "Cell type enhanced" "Detected in many" "leukocyte: 19.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Breast glandular cells, Skin - Keratinocyte (granular), Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006811, HPA025820" Enhanced Enhanced Nucleoplasm NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 77: Intestine - Digestion" "Cluster 6: Non-specific - Immune response" "Cluster 45: Non-specific - Nuclear processes" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 16 Nucleoplasm "HPA006811: , HPA025820: " "unprognostic (5.04e-2)" "unprognostic (4.37e-2)" "unprognostic (2.90e-1)" "unprognostic (6.75e-2)" "unprognostic (9.67e-2)" "unprognostic (1.70e-2)" "unprognostic (3.21e-1)" "unprognostic (7.91e-2)" "unprognostic (6.99e-3)" "unprognostic (2.50e-3)" "potential prognostic favorable (4.14e-5)" "unprognostic (2.09e-1)" "unprognostic (2.65e-1)" "unprognostic (4.23e-2)" "unprognostic (8.22e-3)" "unprognostic (1.29e-1)" "unprognostic (2.65e-2)" "unprognostic (4.99e-2)" "unprognostic (3.39e-1)" "unprognostic (3.48e-1)" "unprognostic (1.59e-1)" "unprognostic (3.13e-3)" "unprognostic (1.29e-1)" "unprognostic (9.20e-2)" "unprognostic (5.73e-3)" "unprognostic (5.76e-2)" "unprognostic (1.00e-1)" "unprognostic (7.73e-2)" "unprognostic (1.07e-1)" "unprognostic (6.44e-2)" "unprognostic (1.29e-1)" ZBTB7C "ZBTB36, ZNF857C" ENSG00000184828 "Zinc finger and BTB domain containing 7C" A1YPR0 18 48026672-48410752 "Predicted intracellular proteins, Transcription factors" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 38.6" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 298.0;Ependymal cells: 297.5;Papillary tip epithelial cells: 358.2;Podocytes: 544.1;Prostatic hillock cells: 293.4;Retinal ganglion cells: 409.5;Sertoli cells: 552.3;Vascular smooth muscle cells: 336.9" "Cell type enhanced" "Detected in all" "ependymal cell: 354.3;vascular associated smooth muscle cell: 369.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 17 "cervical cancer: 137.2" "Adipose visceral - Mesothelial cells, Heart muscle - Smooth muscle cells, Minor Salivary Gland - Minor salivary gland basal cells, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 62: Smooth muscle cells - Muscle contraction" 4 "potential prognostic favorable (2.52e-5)" "unprognostic (1.20e-1)" "unprognostic (6.48e-2)" "unprognostic (4.65e-2)" "unprognostic (1.10e-3)" "unprognostic (1.09e-1)" "unprognostic (1.62e-1)" "unprognostic (1.33e-1)" "unprognostic (7.00e-3)" "unprognostic (7.36e-3)" "unprognostic (6.57e-2)" "unprognostic (1.80e-2)" "unprognostic (6.87e-2)" "unprognostic (1.75e-3)" "unprognostic (2.21e-2)" "unprognostic (1.61e-2)" "unprognostic (2.79e-1)" "unprognostic (9.37e-2)" "unprognostic (1.44e-2)" "potential prognostic favorable (4.23e-6)" "unprognostic (2.03e-1)" "unprognostic (8.18e-2)" "unprognostic (1.76e-3)" "unprognostic (5.79e-2)" "unprognostic (1.37e-1)" "unprognostic (1.05e-2)" "unprognostic (5.73e-2)" "unprognostic (2.38e-2)" ZBTB8A "BOZF1, FLJ90065, ZBTB8, ZNF916A" ENSG00000160062 "Zinc finger and BTB domain containing 8A" Q96BR9 1 32539427-32605941 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hematopoietic stem cells: 27.2;Peritubular myoid cells: 30.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031768, HPA031769, HPA031770" Approved Approved "Nuclear speckles,Focal adhesion sites" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 94: Gonadal somatic cells - Mixed function" 65 "Nuclear speckles, Focal adhesion sites" "HPA031768: , HPA031769: , HPA031770: " "unprognostic (1.19e-3)" "unprognostic (4.38e-2)" "unprognostic (1.92e-1)" "unprognostic (2.76e-2)" "unprognostic (1.83e-1)" "unprognostic (1.21e-2)" "unprognostic (8.37e-2)" "unprognostic (8.28e-2)" "unprognostic (5.61e-2)" "unprognostic (3.98e-3)" "unprognostic (1.29e-1)" "unprognostic (4.50e-3)" "unprognostic (1.10e-1)" "unprognostic (5.26e-3)" "unprognostic (3.25e-2)" "unprognostic (1.65e-1)" "unprognostic (7.70e-2)" "unprognostic (3.53e-1)" "unprognostic (1.05e-1)" "unprognostic (2.49e-2)" "unprognostic (3.78e-2)" "unprognostic (1.38e-3)" "unprognostic (2.76e-2)" "unprognostic (6.65e-2)" "unprognostic (3.92e-2)" "unprognostic (1.27e-1)" "unprognostic (8.12e-2)" "unprognostic (3.29e-1)" "unprognostic (3.39e-2)" "unprognostic (1.44e-1)" "unprognostic (1.25e-1)" ZBTB8B "DKFZp547H154, RP1-27O5.1, ZNF916B" ENSG00000273274 "Zinc finger and BTB domain containing 8B" Q8NAP8 1 32465072-32496686 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027818, HPA028690, HPA055553, HPA071427" Enhanced Enhanced Nucleoplasm,Cytosol NA NA "Cluster 1: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 6 Nucleoplasm Cytosol "HPA027818: , HPA028690: , HPA055553: , HPA071427: " "unprognostic (2.78e-3)" "unprognostic (3.11e-2)" "unprognostic (5.11e-2)" "unprognostic (2.86e-2)" ZBTB8OS ARCH ENSG00000176261 "Zinc finger and BTB domain containing 8 opposite strand" Q8IWT0 1 32600172-32650903 "Essential proteins, Predicted intracellular proteins" "tRNA processing" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046315 Approved Approved "Plasma membrane" NA NA 14000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 76: Non-specific - Metabolism" "Cluster 31: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 97: Non-specific - Cellular respiration" 1 "Plasma membrane" "HPA046315: " "unprognostic (1.58e-1)" "unprognostic (1.81e-1)" "unprognostic (2.65e-2)" "unprognostic (1.01e-2)" "unprognostic (2.11e-1)" "unprognostic (3.03e-3)" "unprognostic (4.59e-3)" "unprognostic (1.17e-1)" "unprognostic (4.06e-2)" "unprognostic (6.21e-3)" "unprognostic (6.96e-3)" "unprognostic (5.84e-2)" "unprognostic (2.25e-1)" "validated prognostic unfavorable (3.83e-7)" "validated prognostic unfavorable (2.37e-4)" "unprognostic (1.04e-2)" "unprognostic (2.58e-1)" "unprognostic (5.98e-3)" "unprognostic (2.39e-1)" "unprognostic (2.72e-1)" "unprognostic (1.96e-2)" "unprognostic (2.79e-2)" "unprognostic (1.28e-2)" "unprognostic (2.66e-1)" "unprognostic (1.05e-1)" "unprognostic (4.22e-2)" "unprognostic (1.79e-2)" "unprognostic (6.38e-2)" "unprognostic (1.16e-1)" "unprognostic (9.39e-2)" "unprognostic (9.42e-2)" ZBTB9 "MGC23166, ZNF919" ENSG00000213588 "Zinc finger and BTB domain containing 9" Q96C00 6 33453970-33457544 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 15.2" "Cell type enhanced" "Detected in some" "Astrocytes: 2.5;Bergmann glia: 1.5;Brain excitatory neurons: 2.7;Brain inhibitory neurons: 1.4;Choroid plexus epithelial cells: 10.9;Ependymal cells: 6.0;Oligodendrocyte progenitor cells: 1.5;Oligodendrocytes: 1.1;Other brain neurons: 1.9" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 19.5" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "choroid plexus: 20.1" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036767, HPA058171" Uncertain Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 20: Pituitary gland - Hormone signaling" "Cluster 23: Choroid plexus - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 37 Nucleoplasm "Nuclear membrane, Cytosol" "HPA036767: , HPA058171: " "unprognostic (9.68e-2)" "unprognostic (6.99e-2)" "unprognostic (5.84e-2)" "unprognostic (3.02e-2)" "unprognostic (5.69e-2)" "unprognostic (1.48e-2)" "unprognostic (9.90e-2)" "unprognostic (1.88e-2)" "unprognostic (2.56e-3)" "unprognostic (4.01e-1)" "potential prognostic unfavorable (3.34e-4)" "unprognostic (2.96e-2)" "unprognostic (1.45e-1)" "unprognostic (6.95e-2)" "unprognostic (5.02e-2)" "unprognostic (1.26e-1)" "unprognostic (1.71e-1)" "unprognostic (2.42e-1)" "unprognostic (2.16e-2)" "unprognostic (1.86e-1)" "unprognostic (3.76e-1)" "unprognostic (3.11e-1)" "unprognostic (4.65e-2)" ZC2HC1A "C8orf70, CGI-62, FAM164A" ENSG00000104427 "Zinc finger C2HC-type containing 1A" Q96GY0 8 78666050-78719765 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fallopian tube ciliated cells: 208.0;Respiratory ciliated cells: 248.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 25.6;T-reg: 19.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024726 Approved Approved "Actin filaments,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 65: Brain - Transcription" "Cluster 24: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 107: Ciliated cells - Cilia assembly & function" 19 Cytosol "Actin filaments" "HPA024726: " "unprognostic (1.40e-3)" "unprognostic (1.88e-1)" "unprognostic (7.53e-2)" "unprognostic (3.74e-2)" "unprognostic (3.13e-1)" "unprognostic (3.21e-1)" "unprognostic (1.39e-1)" "unprognostic (1.15e-1)" "unprognostic (3.22e-1)" "potential prognostic favorable (8.36e-5)" "unprognostic (1.31e-1)" "unprognostic (7.30e-2)" "potential prognostic unfavorable (2.26e-5)" "unprognostic (1.11e-1)" "unprognostic (7.58e-2)" "unprognostic (2.30e-1)" "unprognostic (2.68e-1)" "unprognostic (4.34e-3)" "unprognostic (2.60e-3)" "unprognostic (1.55e-1)" "unprognostic (4.96e-3)" "unprognostic (6.62e-3)" "unprognostic (4.62e-2)" "unprognostic (3.71e-2)" "unprognostic (2.43e-2)" "unprognostic (1.09e-2)" "unprognostic (1.49e-1)" "unprognostic (2.62e-2)" "unprognostic (5.79e-2)" ZC2HC1B "C6orf94, dJ468K18.5, FAM164B" ENSG00000118491 "Zinc finger C2HC-type containing 1B" Q5TFG8 6 143864436-143938343 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 52 "testis: 14.9" "Cell type enhanced" "Detected in some" "Astrocytes: 3.4;Bergmann glia: 5.6;Brain excitatory neurons: 4.2;Brain inhibitory neurons: 6.1;Microglia: 2.3;Oligodendrocyte progenitor cells: 8.6;Oligodendrocytes: 1.3;Other brain neurons: 5.4" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 22 "Myeloma: 2.1" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 109: Neurons - Neuronal signaling" 4 "unprognostic (3.42e-2)" ZC2HC1C "C14orf140, FAM164C" ENSG00000119703 "Zinc finger C2HC-type containing 1C" Q53FD0 14 75064109-75119502 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 22.6;testis: 51.7" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 302.0;Early spermatids: 118.3;Epicardial cells: 161.5;Late primary spermatocytes: 437.9;Late spermatids: 280.2;Myonuclei: 189.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 1.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA050928, HPA065062" Enhanced Approved "Nuclear speckles,Mitochondria" No No "Cluster 22: Epididymis - Mixed function" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 19 "Nuclear speckles" Mitochondria "HPA050928: , HPA065062: " "unprognostic (5.07e-2)" "unprognostic (3.65e-1)" "unprognostic (9.35e-3)" "unprognostic (1.79e-1)" "unprognostic (3.70e-2)" "unprognostic (2.50e-3)" "unprognostic (9.68e-3)" "unprognostic (6.39e-2)" "validated prognostic favorable (4.67e-10)" "validated prognostic favorable (9.59e-4)" "unprognostic (4.47e-2)" "unprognostic (7.40e-2)" "unprognostic (1.09e-2)" "unprognostic (1.10e-1)" "unprognostic (9.06e-3)" "unprognostic (7.79e-2)" "unprognostic (2.52e-1)" "unprognostic (8.67e-2)" "potential prognostic favorable (2.77e-4)" "unprognostic (3.52e-1)" "unprognostic (1.39e-1)" "unprognostic (1.66e-1)" "unprognostic (2.76e-3)" "unprognostic (1.90e-1)" "unprognostic (1.02e-2)" "unprognostic (2.78e-1)" "unprognostic (3.02e-1)" "unprognostic (1.26e-1)" ZC3H10 "FLJ14451, ZC3HDC10" ENSG00000135482 "Zinc finger CCCH-type containing 10" Q96K80 12 56118260-56127514 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Early spermatids: 2.5;Late spermatids: 1.5;Myosatellite cells: 1.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039236, HPA062265" Uncertain Approved Vesicles NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 39: Testis - Nuclear processes" "Cluster 6: Non-specific - Immune response" "Cluster 38: Non-specific - Transcription" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 115 Vesicles "HPA039236: , HPA062265: " "unprognostic (2.18e-1)" "unprognostic (1.30e-2)" "unprognostic (2.71e-1)" "unprognostic (3.11e-3)" "unprognostic (1.64e-1)" "unprognostic (1.10e-2)" "unprognostic (6.08e-2)" "potential prognostic favorable (3.88e-5)" "unprognostic (3.51e-2)" "potential prognostic unfavorable (1.91e-4)" "potential prognostic favorable (1.09e-4)" "unprognostic (2.01e-2)" "unprognostic (1.58e-2)" "unprognostic (4.01e-3)" "unprognostic (1.06e-1)" "unprognostic (4.52e-2)" "unprognostic (1.13e-1)" "unprognostic (2.27e-1)" "unprognostic (3.76e-2)" "unprognostic (4.65e-1)" "unprognostic (6.22e-3)" "unprognostic (1.11e-2)" "unprognostic (2.23e-1)" "unprognostic (2.01e-1)" "unprognostic (5.36e-2)" "unprognostic (1.11e-1)" "unprognostic (4.91e-2)" "unprognostic (1.17e-1)" "unprognostic (5.23e-1)" "unprognostic (2.99e-1)" "unprognostic (7.48e-2)" ZC3H11A "KIAA0663, ZC3HDC11A" ENSG00000058673 "Zinc finger CCCH-type containing 11A" O75152 1 203795623-203854999 "Predicted intracellular proteins" "mRNA transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 13 "Astrocytes: 137.2;Bergmann glia: 140.5;Brain excitatory neurons: 96.8;Brain inhibitory neurons: 85.1;Choroid plexus epithelial cells: 163.7;Ependymal cells: 93.4;Microglia: 101.8;Oligodendrocyte progenitor cells: 127.3;Oligodendrocytes: 179.2;Other brain neurons: 79.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA026439, HPA028490, HPA028526" Approved Approved "Nuclear speckles" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 61: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 22: Non-specific - Basic cellular functions" 47 "Nuclear speckles" "HPA026439: , HPA028490: , HPA028526: " "unprognostic (1.82e-1)" "unprognostic (6.12e-2)" "unprognostic (3.50e-1)" "unprognostic (2.00e-1)" "unprognostic (2.26e-1)" "unprognostic (8.63e-3)" "unprognostic (2.08e-1)" "unprognostic (2.85e-1)" "unprognostic (3.33e-2)" "potential prognostic unfavorable (7.31e-4)" "potential prognostic favorable (4.16e-4)" "unprognostic (3.62e-3)" "unprognostic (1.01e-1)" "unprognostic (1.19e-1)" "unprognostic (4.24e-1)" "unprognostic (1.21e-1)" "unprognostic (1.20e-1)" "unprognostic (1.60e-1)" "unprognostic (3.52e-2)" "unprognostic (5.49e-2)" "unprognostic (9.21e-2)" "unprognostic (2.14e-2)" "unprognostic (5.69e-2)" "unprognostic (7.47e-2)" "unprognostic (1.56e-3)" "unprognostic (3.65e-1)" "unprognostic (1.92e-1)" "unprognostic (1.83e-1)" "unprognostic (4.17e-1)" "unprognostic (1.02e-2)" "unprognostic (6.91e-2)" ZC3H11B ZC3HDC11B ENSG00000215817 "Zinc finger CCCH-type containing 11B" A0A1B0GTU1 1 219608012-219613105 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 14 "testis: 5.4" "Group enriched" "Detected in some" 4 "Distal convoluted tubule cells: 9.3;Late primary spermatocytes: 13.2;Loop of henle epithelial cells: 8.7;Papillary tip epithelial cells: 3.8;Podocytes: 6.7;Proximal tubule cells: 14.2;Renal collecting duct intercalated cells: 9.3;Renal collecting duct principal cells: 4.7;Renal connecting tubule cells: 8.8" "Cell type enhanced" "Detected in single" "pericyte: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "skin cancer: 1.4" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "HPA026439, HPA028490, HPA028526" Uncertain Approved "Nuclear speckles" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 105: Non-specific - Mixed function" "Nuclear speckles" "HPA026439: , HPA028490: , HPA028526: " "unprognostic (1.84e-1)" ZC3H11C ENSG00000214558 "Zinc finger CCCH-type containing 11C" 6 65301476-65306574 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "testis: 5.1" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 6.2;Early spermatids: 12.6;Late primary spermatocytes: 19.7;Neutrophil progenitors: 4.8;Neutrophils: 5.1;Paneth cells: 3.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "HPA026439, HPA028490, HPA028526" Uncertain Approved "Nuclear speckles" NA NA "Cluster 47: Testis - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" "Nuclear speckles" "HPA026439: , HPA028490: , HPA028526: " ZC3H12A "FLJ23231, MCPIP1, Regnase-1" ENSG00000163874 "Zinc finger CCCH-type containing 12A" Q5D1E8 1 37474580-37484377 "Disease related genes, Predicted intracellular proteins" "Angiogenesis, Antiviral defense, Apoptosis, Differentiation, DNA damage, Host-virus interaction, Immunity, Inflammatory response, Neurogenesis, Stress response, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Endonuclease, Hydrolase, Nuclease, Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 128.7" "Cell type enhanced" "Detected in many" "Breast secretory cells: 222.6;Endometrial secretory cells: 242.8;Epididymal basal cells: 350.2;Epididymal clear cells: 224.5;Fallopian secretory cells: 146.3" "Cell type enhanced" "Detected in some" "astrocyte: 4.2;endothelial cell: 5.0;leukocyte: 10.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Neutrophils, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA032052, HPA032053" Uncertain Supported "Nucleoplasm,Cytoplasmic bodies" No No "Cluster 7: Non-specific - Innate immune response" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 20: Non-specific - Transcription regulation" 24 "Cytoplasmic bodies" Nucleoplasm "HPA032052: , HPA032053: " "unprognostic (7.09e-2)" "unprognostic (2.05e-2)" "unprognostic (1.86e-1)" "unprognostic (1.36e-3)" "unprognostic (1.19e-3)" "unprognostic (1.45e-1)" "unprognostic (8.32e-3)" "unprognostic (1.83e-2)" "unprognostic (2.53e-1)" "unprognostic (2.95e-1)" "unprognostic (4.82e-3)" "unprognostic (2.35e-2)" "unprognostic (2.90e-2)" "unprognostic (7.35e-2)" "unprognostic (1.91e-2)" "unprognostic (1.27e-2)" "unprognostic (7.12e-2)" "unprognostic (7.00e-2)" "unprognostic (2.41e-1)" "unprognostic (8.87e-3)" "unprognostic (2.97e-2)" "unprognostic (8.98e-3)" "unprognostic (2.41e-2)" "unprognostic (2.21e-2)" "unprognostic (5.69e-2)" "unprognostic (6.01e-2)" "unprognostic (2.26e-1)" "unprognostic (1.94e-2)" "unprognostic (4.43e-2)" "unprognostic (4.77e-1)" "unprognostic (1.46e-1)" ZC3H12B "CXorf32, MCPIP2" ENSG00000102053 "Zinc finger CCCH-type containing 12B" Q5HYM0 X 65034788-65507887 "Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Corticotrophs: 509.3;Fibro-adipogenic progenitors: 578.4;Gonadotrophs: 456.1;Innate lymphoid cells: 446.5;Lactotrophs: 660.2;Pituitary stem cells: 439.4;Somatotrophs: 713.3;Thyrotrophs: 591.4" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Prostate - Fibroblasts, Skeletal muscle - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA000836 Uncertain Approved "Nucleoli fibrillar center,Golgi apparatus" NA NA "Cluster 65: Brain - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 7: Non-specific - Transcription" "Nucleoli fibrillar center" "Golgi apparatus" "HPA000836: " "unprognostic (3.14e-1)" "unprognostic (1.76e-1)" "unprognostic (1.49e-3)" "unprognostic (2.28e-1)" "unprognostic (2.56e-1)" ZC3H12C "KIAA1726, MCPIP3" ENSG00000149289 "Zinc finger CCCH-type containing 12C" Q9C0D7 11 110093392-110171841 "Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hematopoietic stem cells: 214.5;Melanocytes: 241.0;Urothelial cells: 241.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 36 "basophil: 5.9" "Lineage enriched" "Detected in single" 36 "granulocytes: 5.9" "Low cancer specificity" "Detected in all" "Kidney - Macrophages, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038836, HPA038837" Approved Approved "Nuclear membrane,Golgi apparatus" NA NA "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 72: Neuronal - Signal transduction" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 2 "Nuclear membrane, Golgi apparatus" "HPA038836: , HPA038837: " "unprognostic (2.01e-3)" "unprognostic (1.02e-1)" "unprognostic (2.40e-3)" "unprognostic (1.63e-2)" "unprognostic (2.59e-3)" "unprognostic (1.14e-1)" "unprognostic (2.41e-1)" "unprognostic (3.02e-1)" "unprognostic (1.19e-1)" "unprognostic (9.56e-3)" "validated prognostic favorable (2.16e-10)" "validated prognostic favorable (6.78e-4)" "unprognostic (1.40e-1)" "unprognostic (9.92e-2)" "unprognostic (4.74e-3)" "unprognostic (1.39e-1)" "unprognostic (7.74e-2)" "unprognostic (1.72e-1)" "unprognostic (1.49e-1)" "unprognostic (5.56e-2)" "unprognostic (7.74e-2)" "potential prognostic unfavorable (4.62e-4)" "unprognostic (8.10e-2)" "unprognostic (1.62e-1)" "unprognostic (4.26e-1)" "unprognostic (5.33e-3)" "potential prognostic unfavorable (3.09e-4)" "unprognostic (1.40e-1)" "unprognostic (7.61e-2)" "unprognostic (1.12e-1)" ZC3H12D "C6orf95, dJ281H8.1, MCPIP4" ENSG00000178199 "Zinc finger CCCH-type containing 12D" A2A288 6 149446795-149485014 "Disease related genes, Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 3.4;intestine: 4.4;lymphoid tissue: 11.8" "Cell type enhanced" "Detected in many" "B-cells: 40.3;cDC: 15.7;Colonocytes: 12.7;Enterocytes: 14.0;Kupffer cells: 28.7;Macrophages: 21.9;Microglia: 14.9;monocytes: 11.1;T-cells: 53.4" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 16.1;leukocyte: 18.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 7 "Leukemia: 4.2;lymphoma: 11.5" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Skeletal muscle - Macrophages, Spleen - B-cells (Spleen)" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA036897 Uncertain Supported "Nucleoplasm,Cytoplasmic bodies" NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 9: T-cells - Adaptive immunity: Regulation" 1 "Nucleoplasm, Cytoplasmic bodies" "HPA036897: " "unprognostic (8.36e-3)" "unprognostic (1.19e-2)" "unprognostic (1.11e-1)" "potential prognostic favorable (4.09e-4)" "unprognostic (7.10e-2)" "unprognostic (6.69e-3)" "unprognostic (2.91e-1)" "potential prognostic favorable (5.48e-6)" "unprognostic (5.82e-2)" "unprognostic (5.05e-2)" "unprognostic (7.47e-2)" "validated prognostic favorable (1.73e-4)" "validated prognostic favorable (4.19e-4)" "unprognostic (6.31e-2)" "unprognostic (5.37e-2)" "unprognostic (6.51e-2)" ZC3H13 "DKFZp434D1812, KIAA0853, Xio" ENSG00000123200 "Zinc finger CCCH-type containing 13" Q5T200 13 45954465-46052759 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 493.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039340, HPA040140, HPA047806" Uncertain Supported Nucleoplasm NA NA "Cluster 41: Basophils - Unknown function" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 93: Hepatocytes - Bile production & excretion" 15 Nucleoplasm "HPA039340: , HPA040140: , HPA047806: " "unprognostic (1.49e-2)" "unprognostic (1.05e-1)" "unprognostic (3.19e-1)" "unprognostic (4.04e-3)" "unprognostic (2.09e-1)" "unprognostic (1.88e-1)" "unprognostic (3.41e-2)" "unprognostic (8.67e-2)" "unprognostic (1.90e-1)" "unprognostic (1.41e-3)" "validated prognostic favorable (1.47e-6)" "validated prognostic favorable (1.64e-5)" "unprognostic (1.42e-1)" "unprognostic (2.99e-2)" "potential prognostic favorable (8.66e-5)" "unprognostic (3.49e-1)" "unprognostic (7.74e-2)" "unprognostic (2.88e-1)" "unprognostic (9.47e-2)" "unprognostic (8.19e-2)" "unprognostic (7.97e-2)" "unprognostic (2.46e-2)" "unprognostic (1.17e-2)" "unprognostic (2.32e-1)" "unprognostic (6.54e-2)" "unprognostic (1.41e-2)" "unprognostic (4.62e-2)" "unprognostic (1.55e-1)" "unprognostic (2.47e-1)" "unprognostic (2.94e-1)" "unprognostic (5.35e-3)" ZC3H14 "FLJ11806, NY-REN-37, UKp68" ENSG00000100722 "Zinc finger CCCH-type containing 14" Q6PJT7 14 88562970-88627596 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" RNA-binding "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "testis: 162.0" "Group enriched" "Detected in many" 4 "Early spermatids: 1426.6;Late primary spermatocytes: 915.7;Late spermatids: 599.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049798, HPA053510" Enhanced Enhanced "Nucleoli,Nucleoli rim,Nuclear speckles" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 47: Testis - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 8 "Nuclear speckles" "Nucleoli, Nucleoli rim" "HPA049798: , HPA053510: " "unprognostic (2.26e-2)" "unprognostic (3.44e-2)" "unprognostic (2.29e-1)" "unprognostic (6.33e-2)" "unprognostic (7.07e-2)" "unprognostic (3.53e-1)" "unprognostic (1.15e-1)" "unprognostic (4.26e-2)" "unprognostic (6.25e-2)" "potential prognostic unfavorable (3.86e-5)" "potential prognostic favorable (1.63e-4)" "unprognostic (4.40e-3)" "unprognostic (1.39e-1)" "unprognostic (1.27e-2)" "unprognostic (6.06e-2)" "unprognostic (3.11e-2)" "unprognostic (1.51e-1)" "unprognostic (1.57e-1)" "unprognostic (3.52e-1)" "unprognostic (1.30e-1)" "unprognostic (1.22e-3)" "unprognostic (7.47e-2)" "unprognostic (3.01e-3)" "unprognostic (5.88e-2)" "unprognostic (7.27e-2)" "unprognostic (1.76e-3)" "unprognostic (2.56e-2)" "unprognostic (7.31e-2)" "unprognostic (5.78e-1)" "unprognostic (1.24e-1)" "unprognostic (4.09e-2)" ZC3H15 LEREPO4 ENSG00000065548 "Zinc finger CCCH-type containing 15" Q8WU90 2 186486253-186509361 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 501.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031099, HPA031100, HPA031101" Enhanced Enhanced Cytosol NA Yes "Cluster 9: T-regs - Cell cycle regulation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 34: Non-specific - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 17: Non-specific - RNA processing" 24 Cytosol "HPA031099: , HPA031100: , HPA031101: " "unprognostic (7.06e-2)" "unprognostic (9.38e-3)" "unprognostic (4.71e-2)" "unprognostic (1.01e-3)" "unprognostic (1.95e-1)" "unprognostic (1.05e-2)" "unprognostic (1.62e-1)" "unprognostic (1.46e-1)" "unprognostic (9.01e-2)" "potential prognostic unfavorable (4.84e-4)" "potential prognostic favorable (8.83e-5)" "unprognostic (1.17e-1)" "unprognostic (2.12e-3)" "validated prognostic unfavorable (3.76e-6)" "validated prognostic unfavorable (8.06e-5)" "potential prognostic unfavorable (2.04e-5)" "unprognostic (7.06e-3)" "unprognostic (4.22e-1)" "unprognostic (4.02e-2)" "unprognostic (7.69e-3)" "unprognostic (1.14e-1)" "unprognostic (5.10e-3)" "unprognostic (6.07e-3)" "potential prognostic unfavorable (2.32e-4)" "unprognostic (7.05e-2)" "unprognostic (1.06e-1)" "unprognostic (3.92e-2)" "unprognostic (2.35e-1)" "unprognostic (3.68e-1)" "unprognostic (8.22e-2)" "unprognostic (3.37e-1)" ZC3H18 NHN1 ENSG00000158545 "Zinc finger CCCH-type containing 18" Q86VM9 16 88570403-88631964 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 204.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040847, HPA041327" Enhanced Enhanced "Nuclear speckles" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 67: Testis - Mixed function" "Cluster 16: Non-specific - Transcription" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 168 "Nuclear speckles" "HPA040847: , HPA041327: " "unprognostic (2.38e-1)" "unprognostic (9.55e-2)" "unprognostic (5.30e-1)" "unprognostic (1.47e-2)" "unprognostic (3.18e-2)" "unprognostic (1.10e-1)" "unprognostic (3.93e-1)" "unprognostic (5.08e-2)" "unprognostic (9.79e-2)" "unprognostic (1.04e-1)" "potential prognostic favorable (3.01e-5)" "unprognostic (4.95e-2)" "unprognostic (6.66e-3)" "potential prognostic unfavorable (7.02e-5)" "unprognostic (3.50e-2)" "unprognostic (4.28e-2)" "unprognostic (3.04e-2)" "unprognostic (1.12e-2)" "unprognostic (7.99e-3)" "unprognostic (9.37e-2)" "unprognostic (6.17e-2)" "unprognostic (1.11e-1)" "unprognostic (1.83e-3)" "unprognostic (4.69e-3)" "unprognostic (8.29e-2)" "unprognostic (1.80e-1)" "unprognostic (3.65e-2)" "unprognostic (1.59e-1)" "unprognostic (3.72e-1)" "unprognostic (1.08e-1)" "unprognostic (4.26e-2)" ZC3H3 "KIAA0150, ZC3HDC3" ENSG00000014164 "Zinc finger CCCH-type containing 3" Q8IXZ2 8 143437659-143541447 "Essential proteins, Predicted intracellular proteins" "mRNA transport, Transport" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 95.1;Ocular epithelial cells: 106.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023658, HPA050577" Uncertain Approved Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 48: Non-specific - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 100: Stratified epithelial cells - Barrier functions" 124 Nucleoplasm "HPA023658: , HPA050577: " "unprognostic (7.88e-2)" "unprognostic (1.02e-1)" "unprognostic (1.71e-1)" "unprognostic (1.69e-3)" "unprognostic (3.12e-2)" "unprognostic (6.29e-2)" "unprognostic (1.43e-1)" "unprognostic (1.72e-2)" "unprognostic (2.06e-1)" "unprognostic (1.78e-2)" "potential prognostic unfavorable (3.90e-7)" "unprognostic (1.05e-1)" "unprognostic (1.03e-1)" "unprognostic (4.71e-3)" "unprognostic (1.42e-1)" "unprognostic (4.32e-3)" "unprognostic (7.42e-2)" "unprognostic (3.03e-3)" "unprognostic (1.62e-1)" "unprognostic (3.97e-1)" "unprognostic (3.46e-2)" "unprognostic (2.68e-1)" "potential prognostic unfavorable (1.58e-4)" "unprognostic (9.07e-2)" "unprognostic (8.18e-2)" "unprognostic (3.77e-2)" "unprognostic (2.49e-1)" "unprognostic (6.82e-2)" "unprognostic (1.85e-1)" "unprognostic (1.52e-2)" "unprognostic (9.33e-2)" ZC3H4 "C19orf7, KIAA1064" ENSG00000130749 "Zinc finger CCCH-type containing 4" Q9UPT8 19 47064187-47113776 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Transcription termination" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040934, HPA041068" Supported Enhanced Nucleoplasm,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 64: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 4: Non-specific - Transcription" "Cluster 65: Non-specific - Cell growth & division" 26 Nucleoplasm Cytosol "HPA040934: , HPA041068: " "unprognostic (1.97e-2)" "unprognostic (2.97e-2)" "unprognostic (4.02e-2)" "unprognostic (1.93e-1)" "unprognostic (2.14e-1)" "unprognostic (3.06e-1)" "unprognostic (3.02e-1)" "unprognostic (1.52e-1)" "unprognostic (2.56e-3)" "unprognostic (2.50e-1)" "unprognostic (4.07e-3)" "unprognostic (4.00e-3)" "unprognostic (9.86e-2)" "unprognostic (4.22e-2)" "unprognostic (1.97e-1)" "unprognostic (5.74e-2)" "unprognostic (2.98e-2)" "unprognostic (2.09e-2)" "unprognostic (2.50e-2)" "unprognostic (3.74e-1)" "unprognostic (3.65e-1)" "unprognostic (1.10e-1)" "unprognostic (1.19e-1)" "unprognostic (4.82e-2)" "unprognostic (3.72e-2)" "unprognostic (1.20e-2)" "unprognostic (2.16e-1)" "unprognostic (7.00e-2)" "unprognostic (2.22e-1)" "unprognostic (1.05e-1)" "unprognostic (2.30e-2)" ZC3H6 "FLJ41410, FLJ45877, KIAA2035, ZC3HDC6" ENSG00000188177 "Zinc finger CCCH-type containing 6" P61129 2 112275597-112340063 "Predicted intracellular proteins, Transcription factors" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036019, HPA036020, HPA076065" Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 7: Non-specific - Transcription" "Nucleoplasm, Golgi apparatus" "HPA036019: , HPA036020: , HPA076065: " "unprognostic (9.94e-3)" "unprognostic (9.81e-2)" "unprognostic (1.24e-1)" "unprognostic (4.55e-2)" "potential prognostic unfavorable (6.34e-4)" "unprognostic (6.34e-2)" "unprognostic (2.95e-1)" "unprognostic (2.32e-1)" "unprognostic (1.48e-1)" "unprognostic (1.02e-2)" "unprognostic (1.74e-3)" "unprognostic (2.31e-2)" "unprognostic (1.87e-2)" "unprognostic (2.73e-2)" "unprognostic (3.03e-1)" "unprognostic (8.35e-2)" "unprognostic (1.50e-1)" "unprognostic (9.52e-2)" "unprognostic (4.43e-2)" "unprognostic (1.90e-2)" "unprognostic (6.46e-2)" "unprognostic (1.60e-1)" "unprognostic (2.80e-1)" "unprognostic (3.04e-2)" "unprognostic (3.90e-2)" "unprognostic (4.79e-2)" "unprognostic (1.77e-1)" "unprognostic (4.76e-2)" "unprognostic (3.48e-2)" ZC3H7A "FLJ20318, HSPC055, ZC3H7, ZC3HDC7" ENSG00000122299 "Zinc finger CCCH-type containing 7A" Q8IWR0 16 11750586-11797258 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040808, HPA059849" Supported Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 61: Non-specific - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 4 Cytosol "HPA040808: , HPA059849: " "unprognostic (9.51e-2)" "unprognostic (5.17e-3)" "unprognostic (1.18e-1)" "unprognostic (7.70e-2)" "unprognostic (3.14e-1)" "unprognostic (2.59e-1)" "unprognostic (2.05e-1)" "unprognostic (3.01e-1)" "unprognostic (4.98e-2)" "unprognostic (3.31e-3)" "potential prognostic favorable (3.02e-4)" "unprognostic (2.17e-2)" "unprognostic (1.16e-1)" "unprognostic (1.24e-1)" "unprognostic (1.78e-1)" "unprognostic (2.04e-2)" "unprognostic (1.51e-1)" "unprognostic (1.83e-1)" "unprognostic (6.43e-2)" "unprognostic (6.73e-2)" "unprognostic (6.33e-2)" "unprognostic (1.35e-1)" "potential prognostic unfavorable (9.51e-4)" "unprognostic (1.42e-1)" "unprognostic (3.56e-2)" "unprognostic (2.60e-1)" "unprognostic (6.84e-2)" "unprognostic (2.68e-2)" "unprognostic (1.30e-1)" "unprognostic (6.14e-3)" "unprognostic (1.32e-1)" ZC3H7B "DKFZp434K0920, FLJ13787, KIAA1031, RoXaN" ENSG00000100403 "Zinc finger CCCH-type containing 7B" Q9UGR2 22 41301525-41360147 "Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001784, HPA076092" Uncertain Uncertain Cytosol NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 24: Neurons - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 18: Adrenal cortex cells - Steroidogensis" 2 Cytosol "HPA001784: , HPA076092: " "unprognostic (4.81e-2)" "unprognostic (9.41e-2)" "unprognostic (5.43e-2)" "unprognostic (1.11e-2)" "unprognostic (5.10e-3)" "unprognostic (7.18e-2)" "unprognostic (6.04e-2)" "unprognostic (3.85e-2)" "unprognostic (2.18e-1)" "unprognostic (6.38e-2)" "potential prognostic favorable (2.30e-6)" "unprognostic (1.22e-3)" "unprognostic (2.48e-3)" "unprognostic (7.92e-3)" "unprognostic (2.43e-1)" "unprognostic (2.65e-1)" "unprognostic (1.62e-1)" "unprognostic (4.06e-1)" "potential prognostic favorable (3.97e-5)" "unprognostic (2.02e-1)" "unprognostic (4.79e-1)" "unprognostic (3.44e-2)" "unprognostic (1.05e-1)" "unprognostic (3.09e-1)" "unprognostic (8.39e-3)" "unprognostic (4.19e-2)" "unprognostic (4.01e-1)" "unprognostic (3.15e-2)" "unprognostic (3.46e-1)" "unprognostic (8.82e-2)" "unprognostic (2.62e-3)" ZC3H8 "Fliz1, ZC3HDC8" ENSG00000144161 "Zinc finger CCCH-type containing 8" Q8N5P1 2 112211529-112255136 "Essential proteins, Predicted intracellular proteins, Transcription factors" "Apoptosis, Transcription, Transcription regulation" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034803, HPA034804" Approved Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 37: Neurons - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 9: T-cells - Adaptive immunity: Regulation" 15 Nucleoplasm "Nuclear bodies" "HPA034803: , HPA034804: " "unprognostic (1.49e-1)" "unprognostic (1.68e-2)" "unprognostic (1.70e-1)" "unprognostic (3.63e-1)" "unprognostic (2.21e-2)" "unprognostic (1.14e-1)" "unprognostic (1.35e-1)" "unprognostic (1.36e-2)" "unprognostic (9.76e-2)" "unprognostic (4.91e-3)" "unprognostic (2.03e-2)" "unprognostic (6.66e-3)" "unprognostic (7.83e-3)" "unprognostic (2.72e-3)" "unprognostic (2.80e-1)" "unprognostic (2.04e-2)" "unprognostic (3.70e-3)" "unprognostic (1.42e-1)" "unprognostic (4.31e-2)" "unprognostic (8.07e-2)" "unprognostic (1.95e-1)" "unprognostic (8.79e-3)" "unprognostic (8.39e-3)" "unprognostic (3.62e-2)" "unprognostic (1.04e-2)" "unprognostic (2.48e-1)" "unprognostic (5.04e-3)" "unprognostic (2.31e-2)" "unprognostic (5.01e-2)" "unprognostic (1.53e-2)" "unprognostic (2.76e-1)" ZC3HAV1 "ARTD13, FLB6421, FLJ13288, MGC48898, PARP13, ZAP, ZC3H2, ZC3HDC2" ENSG00000105939 "Zinc finger CCCH-type containing, antiviral 1" Q7Z2W4 7 139043515-139132122 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 81.0" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 980.0;Endometrial luminal cells: 738.9;Neutrophils: 583.1;NK-cells: 431.8;pDCs: 428.1;T-cells: 635.2" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 173.5;endothelial cell: 158.4;leukocyte: 410.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skin - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047818, HPA059096" Approved Supported "Golgi apparatus,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 15: Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 51: Secretory epithelial cells - Mixed function" 163 Cytosol "Golgi apparatus" "HPA047818: , HPA059096: " "unprognostic (4.86e-2)" "unprognostic (2.73e-1)" "unprognostic (1.92e-1)" "unprognostic (7.94e-2)" "unprognostic (1.17e-2)" "unprognostic (5.79e-3)" "unprognostic (2.30e-1)" "unprognostic (9.02e-3)" "unprognostic (1.26e-1)" "unprognostic (2.53e-2)" "unprognostic (3.69e-3)" "unprognostic (4.29e-3)" "unprognostic (1.72e-1)" "potential prognostic unfavorable (2.50e-6)" "unprognostic (1.30e-1)" "unprognostic (4.41e-3)" "unprognostic (3.38e-3)" "unprognostic (4.85e-2)" "unprognostic (3.24e-1)" "unprognostic (2.94e-1)" "unprognostic (6.58e-2)" "unprognostic (3.68e-2)" "unprognostic (6.55e-2)" "unprognostic (1.79e-2)" "unprognostic (1.96e-1)" "unprognostic (9.80e-3)" "unprognostic (2.85e-1)" "unprognostic (1.70e-2)" "unprognostic (1.30e-1)" "unprognostic (9.96e-2)" "unprognostic (1.94e-1)" ZC3HAV1L "C7orf39, MGC14289" ENSG00000146858 "Zinc finger CCCH-type containing, antiviral 1 like" Q96H79 7 139025706-139036042 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 16.9;Adrenal medulla cells: 10.6;Gonadotrophs: 10.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 11 "basophil: 10.2" "Lineage enriched" "Detected in single" 11 "granulocytes: 10.2" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA020386, HPA050741" Uncertain Enhanced Cytosol NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 75: Ovary - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 1 Cytosol "HPA020386: , HPA050741: " "unprognostic (1.75e-1)" "unprognostic (3.24e-1)" "unprognostic (3.37e-1)" "potential prognostic unfavorable (4.28e-5)" "unprognostic (1.35e-1)" "unprognostic (1.90e-1)" "unprognostic (4.19e-2)" "unprognostic (6.47e-2)" "unprognostic (5.36e-2)" "unprognostic (2.89e-3)" "unprognostic (6.37e-2)" "unprognostic (3.22e-1)" "unprognostic (7.51e-2)" "potential prognostic unfavorable (4.98e-4)" "unprognostic (2.41e-1)" "unprognostic (3.83e-3)" "unprognostic (2.48e-1)" "unprognostic (1.72e-3)" "unprognostic (3.09e-2)" "unprognostic (1.01e-2)" "unprognostic (5.45e-2)" "unprognostic (1.63e-2)" "unprognostic (5.88e-3)" "unprognostic (1.90e-3)" "unprognostic (7.26e-2)" "unprognostic (1.24e-1)" "unprognostic (4.62e-2)" "unprognostic (1.78e-2)" ZC3HC1 NIPA ENSG00000091732 "Zinc finger C3HC-type containing 1" Q86WB0 7 130018287-130051451 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 71.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019089, HPA024023" Enhanced Supported "Nucleoplasm,Nuclear membrane" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 39: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 60 "Nucleoplasm, Nuclear membrane" "HPA019089: , HPA024023: " "unprognostic (2.35e-1)" "unprognostic (6.03e-2)" "unprognostic (1.35e-2)" "unprognostic (6.99e-2)" "unprognostic (9.66e-2)" "unprognostic (5.72e-2)" "unprognostic (4.64e-2)" "unprognostic (8.72e-2)" "unprognostic (3.35e-1)" "unprognostic (5.59e-3)" "unprognostic (8.04e-3)" "unprognostic (2.53e-2)" "unprognostic (1.61e-2)" "validated prognostic unfavorable (2.90e-9)" "validated prognostic unfavorable (9.28e-4)" "unprognostic (1.67e-2)" "unprognostic (2.55e-3)" "unprognostic (6.69e-2)" "unprognostic (3.24e-1)" "unprognostic (8.48e-2)" "unprognostic (2.24e-1)" "unprognostic (2.54e-2)" "unprognostic (8.65e-3)" "unprognostic (9.65e-2)" "unprognostic (3.96e-1)" "unprognostic (2.42e-1)" "unprognostic (4.65e-2)" "unprognostic (7.97e-2)" "unprognostic (4.78e-2)" "unprognostic (6.91e-2)" "unprognostic (1.26e-1)" ZC4H2 "HCA127, KIAA1166, MCS, MRXS4, WWS" ENSG00000126970 "Zinc finger C4H2-type containing" Q9NQZ6 X 64915802-65034713 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Differentiation "Developmental protein" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 190.7;Cone photoreceptor cells: 126.3;Gonadotrophs: 129.9;Somatotrophs: 125.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049584 Approved Approved "Vesicles,Microtubules,Primary cilium,Basal body" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 65: Brain - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 7: Non-specific - Transcription" 18 "Vesicles, Microtubules, Primary cilium" "Basal body" "HPA049584: " "unprognostic (1.51e-3)" "unprognostic (2.07e-2)" "unprognostic (3.82e-2)" "unprognostic (9.19e-3)" "unprognostic (6.70e-2)" "unprognostic (5.27e-2)" "unprognostic (4.77e-2)" "potential prognostic favorable (1.28e-4)" "unprognostic (7.72e-2)" "unprognostic (1.23e-1)" "potential prognostic favorable (3.53e-5)" "unprognostic (2.17e-2)" "unprognostic (3.54e-2)" "unprognostic (1.98e-3)" "unprognostic (1.24e-2)" "unprognostic (1.09e-1)" "unprognostic (5.92e-3)" "unprognostic (2.01e-3)" "unprognostic (2.32e-2)" "unprognostic (1.12e-1)" "unprognostic (3.22e-1)" "unprognostic (3.24e-2)" "unprognostic (2.53e-1)" "unprognostic (5.67e-2)" "unprognostic (3.61e-2)" "unprognostic (1.97e-1)" "unprognostic (1.27e-1)" "unprognostic (9.10e-2)" "potential prognostic unfavorable (9.61e-4)" "unprognostic (4.80e-2)" ZCCHC10 FLJ20094 ENSG00000155329 "Zinc finger CCHC-type containing 10" Q8TBK6 5 132996985-133026604 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 227.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038944 Approved Approved "Nucleoplasm,Nucleoli rim" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 16: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 72 "Nucleoli rim" Nucleoplasm "HPA038944: " "unprognostic (1.37e-1)" "unprognostic (1.16e-1)" "unprognostic (2.03e-1)" "unprognostic (2.11e-1)" "unprognostic (5.01e-2)" "unprognostic (6.30e-3)" "unprognostic (3.12e-1)" "unprognostic (5.24e-2)" "unprognostic (1.80e-3)" "potential prognostic unfavorable (8.20e-5)" "potential prognostic favorable (2.08e-5)" "unprognostic (3.53e-2)" "unprognostic (9.58e-3)" "unprognostic (7.62e-2)" "unprognostic (2.55e-2)" "unprognostic (4.29e-2)" "unprognostic (1.80e-1)" "unprognostic (5.42e-2)" "unprognostic (2.73e-1)" "unprognostic (1.25e-1)" "unprognostic (9.25e-3)" "unprognostic (2.88e-1)" "unprognostic (2.60e-3)" "unprognostic (1.17e-1)" "unprognostic (2.96e-2)" "potential prognostic unfavorable (2.29e-4)" "unprognostic (4.71e-2)" "unprognostic (2.13e-1)" "unprognostic (1.63e-1)" "unprognostic (1.62e-1)" "unprognostic (4.58e-1)" ZCCHC12 "FLJ16123, PNMA7A, SIZN, SIZN1" ENSG00000174460 "Zinc finger CCHC-type containing 12" Q6PEW1 X 118823824-118826968 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 149.6;endometrium 1: 92.6;fallopian tube: 257.5;smooth muscle: 132.4" "Group enriched" "Detected in some" 4 "Epididymal efferent duct absorptive cells: 126.3;Smooth muscle cells: 349.0" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in some" 74 "Thyroid Carcinoma (TCGA): 402.5" "Region enriched" "Detected in all" 6 "hypothalamus: 631.4" "Immune cell enriched" "Detected in single" 6 "naive CD8 T-cell: 1.2" "Lineage enriched" "Detected in single" 7 "T-cells: 1.2" "Cancer enhanced" "Detected in some" "Bone cancer: 8.6;thyroid cancer: 5.7" "Colon - Colon enteroendocrine cells" "HPA031016, HPA034940" Uncertain Approved "Nuclear bodies" NA NA "Cluster 65: Brain - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 62: Smooth muscle cells - Muscle contraction" 26 "Nuclear bodies" "HPA031016: , HPA034940: " "unprognostic (1.59e-1)" "potential prognostic unfavorable (4.54e-4)" "unprognostic (1.46e-1)" "unprognostic (8.94e-3)" "unprognostic (6.03e-2)" "unprognostic (1.29e-1)" "potential prognostic favorable (4.73e-5)" "unprognostic (3.74e-2)" ZCCHC13 "4930513O09RIK, Cnbp2, ZNF9L" ENSG00000187969 "Zinc finger CCHC-type containing 13" Q8WW36 X 74304180-74305034 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 214 "testis: 21.4" "Group enriched" "Detected in some" 7 "Early spermatids: 267.3;Late spermatids: 994.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA003382 Enhanced NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 3 "HPA003382: " ZCCHC14 "BDG29, MGC14139" ENSG00000140948 "Zinc finger CCHC-type containing 14" Q8WYQ9 16 87406246-87493024 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014122 Uncertain "Nuclear membrane" NA NA "Cluster 67: Testis - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 9 "Nuclear membrane" "HPA014122: " "unprognostic (8.05e-2)" "unprognostic (4.20e-2)" "unprognostic (3.64e-1)" "unprognostic (3.28e-1)" "unprognostic (1.92e-1)" "unprognostic (3.10e-1)" "unprognostic (3.22e-1)" "unprognostic (1.13e-3)" "unprognostic (1.74e-1)" "unprognostic (1.29e-1)" "validated prognostic favorable (5.70e-9)" "validated prognostic favorable (4.70e-4)" "unprognostic (2.79e-2)" "unprognostic (1.09e-1)" "unprognostic (3.11e-2)" "unprognostic (7.64e-2)" "unprognostic (1.80e-2)" "unprognostic (4.88e-2)" "unprognostic (6.06e-2)" "unprognostic (2.08e-2)" "unprognostic (2.87e-2)" "unprognostic (3.55e-1)" "unprognostic (9.34e-2)" "unprognostic (5.66e-2)" "unprognostic (1.36e-2)" "unprognostic (5.21e-2)" "unprognostic (1.96e-1)" "unprognostic (9.02e-2)" "unprognostic (2.70e-1)" "unprognostic (7.83e-2)" "unprognostic (4.89e-2)" ZCCHC17 "HSPC251, pNO40, PS1D" ENSG00000121766 "Zinc finger CCHC-type containing 17" Q9NP64 1 31296982-31364953 "Predicted intracellular proteins" Ribonucleoprotein "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 137.7" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 339.7;Early primary spermatocytes: 343.9;Platelets: 357.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053727 Approved NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 14: Neurons - Synaptic function" "Cluster 69: Skin cancer - ECM organization" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 29 "HPA053727: " "unprognostic (3.76e-1)" "unprognostic (2.04e-1)" "unprognostic (5.50e-3)" "unprognostic (1.54e-2)" "unprognostic (5.58e-2)" "unprognostic (3.08e-1)" "unprognostic (2.67e-1)" "unprognostic (3.14e-2)" "unprognostic (2.73e-1)" "unprognostic (4.58e-3)" "potential prognostic favorable (1.78e-4)" "unprognostic (8.67e-3)" "unprognostic (2.93e-2)" "validated prognostic unfavorable (3.28e-9)" "validated prognostic unfavorable (2.98e-4)" "unprognostic (1.35e-1)" "unprognostic (1.33e-2)" "unprognostic (9.16e-2)" "unprognostic (4.40e-1)" "unprognostic (1.20e-2)" "unprognostic (2.19e-1)" "unprognostic (1.15e-1)" "unprognostic (3.01e-1)" "unprognostic (1.72e-1)" "unprognostic (8.46e-2)" "unprognostic (1.44e-3)" "unprognostic (8.13e-2)" "unprognostic (5.22e-2)" "unprognostic (1.22e-1)" "unprognostic (1.41e-1)" "unprognostic (1.93e-2)" ZCCHC18 "PNMA7B, SIZN2" ENSG00000166707 "Zinc finger CCHC-type containing 18" P0CG32 X 104112131-104115842 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 5.4;ovary: 4.1" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 10.6;Astrocytes: 6.1;B-cells: 4.0;Bergmann glia: 5.4;Brain excitatory neurons: 4.3;Brain inhibitory neurons: 4.4;Ependymal cells: 4.7;Neuroendocrine cells: 4.0;Oligodendrocyte progenitor cells: 3.5;Other brain neurons: 6.9;Pancreatic islet cells: 5.5;Retinal amacrine cells: 4.7;Sertoli cells: 3.9" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in single" "Glioblastoma Multiforme (TCGA): 2.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Neuroblastoma: 3.4" "Spleen - B-cells (Spleen), Stomach - Fibroblasts, Thyroid gland - T-cells" "HPA034940, HPA078516" Uncertain Approved Vesicles NA NA "Cluster 24: Non-specific - Transcription" "Cluster 65: Brain - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 98: Neurons - Neurotransmission & signaling" Vesicles "HPA034940: , HPA078516: " "unprognostic (7.11e-2)" "unprognostic (1.91e-1)" "potential prognostic favorable (2.99e-4)" ZCCHC2 "C18orf49, FLJ20222, FLJ20281, KIAA1744" ENSG00000141664 "Zinc finger CCHC-type containing 2" Q9C0B9 18 62523025-62587709 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 223.4;Salivary acinar cells: 251.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Skin - Eccrine sweat gland cells, Spleen - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040711, HPA040943" Uncertain Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 11: White matter - Signal transduction" "Cluster 13: Non-specific - Mixed function" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 1 Nucleoli "Nucleoplasm, Nucleoli rim, Cytosol" "HPA040711: , HPA040943: " "unprognostic (2.71e-1)" "unprognostic (7.49e-2)" "unprognostic (7.60e-3)" "unprognostic (1.05e-2)" "unprognostic (2.10e-2)" "unprognostic (2.06e-1)" "unprognostic (1.30e-1)" "unprognostic (1.58e-1)" "unprognostic (1.22e-1)" "unprognostic (3.37e-1)" "unprognostic (5.20e-3)" "unprognostic (6.14e-2)" "unprognostic (4.37e-2)" "unprognostic (3.50e-2)" "unprognostic (2.92e-1)" "unprognostic (8.80e-2)" "unprognostic (7.08e-2)" "unprognostic (1.34e-1)" "unprognostic (9.26e-3)" "unprognostic (2.53e-1)" "unprognostic (3.56e-1)" "unprognostic (1.65e-1)" "potential prognostic unfavorable (1.90e-4)" "unprognostic (5.83e-2)" "unprognostic (3.58e-2)" "unprognostic (1.79e-2)" "unprognostic (4.87e-2)" "unprognostic (1.87e-1)" "unprognostic (5.48e-2)" "unprognostic (5.03e-2)" "unprognostic (2.25e-2)" ZCCHC24 "C10orf56, FLJ90798, Z3CXXC8" ENSG00000165424 "Zinc finger CCHC-type containing 24" Q8N2G6 10 79382325-79445624 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 122.3" "Cell type enhanced" "Detected in many" "Bergmann glia: 132.4;Endometrial stromal cells: 80.1;Fibro-adipogenic progenitors: 129.4;Fibroblasts: 97.1;Hepatocytes: 86.6;Leydig cells: 89.9;Oligodendrocyte progenitor cells: 312.3;Oligodendrocytes: 215.4;Peritubular myoid cells: 81.4;Schwann cells: 117.1;Smooth muscle cells: 116.4" "Cell type enhanced" "Detected in many" "fibroblast: 280.3;oligodendrocyte: 271.1;oligodendrocyte precursor cell: 361.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Minor Salivary Gland - Endothelial cells, Pituitary gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038348 Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" Mitochondria Nucleoplasm "HPA038348: " "unprognostic (6.38e-3)" "unprognostic (3.23e-2)" "unprognostic (1.71e-2)" "unprognostic (1.15e-2)" "unprognostic (8.63e-2)" "unprognostic (1.29e-1)" "unprognostic (2.04e-1)" "unprognostic (2.40e-3)" "unprognostic (6.19e-2)" "unprognostic (2.69e-1)" "unprognostic (3.06e-1)" "unprognostic (1.08e-1)" "unprognostic (4.39e-2)" "unprognostic (5.07e-2)" "unprognostic (3.82e-2)" "unprognostic (5.90e-2)" "unprognostic (7.06e-2)" "unprognostic (3.97e-2)" "unprognostic (8.59e-2)" "validated prognostic unfavorable (3.11e-4)" "validated prognostic unfavorable (3.29e-4)" "unprognostic (6.80e-2)" "unprognostic (1.38e-1)" "unprognostic (2.16e-1)" "unprognostic (2.62e-1)" "unprognostic (4.94e-3)" "unprognostic (3.21e-1)" "unprognostic (1.21e-2)" "unprognostic (5.04e-2)" "unprognostic (7.72e-3)" "unprognostic (1.28e-1)" ZCCHC3 "C20orf99, dJ1103G7.7" ENSG00000247315 "Zinc finger CCHC-type containing 3" Q9NUD5 20 297570-300321 "Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042972 Approved Vesicles NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 62: Non-specific - Plasma proteins" "Cluster 17: Non-specific - RNA processing" 39 Vesicles "HPA042972: " "unprognostic (3.32e-1)" "unprognostic (4.45e-2)" "unprognostic (4.12e-1)" "unprognostic (8.38e-2)" "unprognostic (2.35e-2)" "unprognostic (7.16e-3)" "unprognostic (3.17e-1)" "unprognostic (2.01e-1)" "unprognostic (9.94e-2)" "potential prognostic favorable (1.32e-4)" "unprognostic (1.24e-2)" "unprognostic (2.21e-1)" "unprognostic (1.01e-3)" "potential prognostic unfavorable (5.96e-5)" "unprognostic (2.59e-1)" "unprognostic (2.12e-1)" "unprognostic (1.16e-1)" "unprognostic (2.31e-2)" "unprognostic (7.30e-2)" "unprognostic (3.11e-1)" "potential prognostic favorable (5.70e-4)" "unprognostic (2.64e-1)" "unprognostic (3.70e-2)" "unprognostic (2.34e-1)" "unprognostic (1.50e-1)" "unprognostic (2.24e-1)" "unprognostic (1.78e-1)" "unprognostic (2.14e-1)" "unprognostic (1.89e-1)" "unprognostic (6.78e-3)" ZCCHC4 "FLJ23024, HSPC052, ZGRF4" ENSG00000168228 "Zinc finger CCHC-type containing 4" Q9H5U6 4 25312774-25370383 "Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 45.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035575, HPA035576" Uncertain Approved "Nuclear speckles,Golgi apparatus" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 7: Non-specific - Transcription" "Nuclear speckles, Golgi apparatus" "HPA035575: , HPA035576: " "unprognostic (1.48e-1)" "unprognostic (8.79e-2)" "unprognostic (1.44e-2)" "unprognostic (1.89e-2)" "unprognostic (1.45e-1)" "unprognostic (1.69e-2)" "unprognostic (1.14e-1)" "unprognostic (1.49e-1)" "unprognostic (1.23e-1)" "unprognostic (4.75e-2)" "unprognostic (4.82e-3)" "potential prognostic favorable (3.01e-4)" "unprognostic (2.83e-2)" "potential prognostic unfavorable (9.45e-4)" "unprognostic (9.76e-2)" "unprognostic (7.01e-2)" "unprognostic (2.37e-2)" "unprognostic (3.43e-1)" "unprognostic (1.81e-1)" "unprognostic (7.38e-2)" "unprognostic (2.55e-1)" "unprognostic (6.22e-2)" "unprognostic (1.84e-2)" "unprognostic (1.34e-1)" "potential prognostic favorable (4.65e-4)" "unprognostic (5.53e-3)" "unprognostic (1.78e-1)" "unprognostic (7.14e-2)" "unprognostic (3.67e-1)" "unprognostic (7.48e-2)" "unprognostic (1.69e-1)" ZCCHC7 "AIR1, FLJ22611" ENSG00000147905 "Zinc finger CCHC-type containing 7" Q8N3Z6 9 37120574-37358149 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pituicytes/FSCs: 1201.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020600, HPA021088, HPA029522" Uncertain Enhanced Nucleoli,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 39: Testis - Nuclear processes" "Cluster 16: Non-specific - Transcription" "Cluster 35: RS4;11 - Unknown function" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 20 "Nucleoli, Cytosol" "HPA020600: , HPA021088: , HPA029522: " "unprognostic (1.36e-1)" "unprognostic (1.69e-1)" "unprognostic (4.60e-2)" "unprognostic (3.28e-2)" "unprognostic (2.21e-2)" "unprognostic (1.77e-1)" "unprognostic (8.26e-2)" "unprognostic (5.78e-2)" "unprognostic (1.60e-1)" "potential prognostic unfavorable (4.32e-4)" "potential prognostic favorable (1.75e-5)" "unprognostic (3.31e-2)" "unprognostic (6.62e-2)" "potential prognostic unfavorable (6.36e-4)" "unprognostic (1.56e-1)" "unprognostic (1.10e-1)" "potential prognostic unfavorable (1.04e-4)" "unprognostic (5.79e-2)" "unprognostic (3.00e-1)" "unprognostic (1.21e-1)" "unprognostic (3.77e-1)" "unprognostic (5.76e-2)" "unprognostic (2.76e-2)" "unprognostic (2.37e-1)" "unprognostic (2.51e-2)" "unprognostic (6.92e-2)" "unprognostic (6.15e-2)" "unprognostic (1.37e-1)" "unprognostic (5.33e-1)" "unprognostic (1.09e-3)" "unprognostic (3.08e-1)" ZCCHC8 DKFZp434E2220 ENSG00000033030 "Zinc finger CCHC-type containing 8" Q6NZY4 12 122471599-122501073 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 41.2" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pancreas - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037483, HPA037484" Supported Enhanced Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 15: Bone marrow - Innate immune response" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 38: Non-specific - Transcription" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 65 Nucleoplasm "HPA037483: , HPA037484: " "unprognostic (4.81e-2)" "unprognostic (5.95e-2)" "unprognostic (1.63e-1)" "unprognostic (4.73e-2)" "unprognostic (1.61e-1)" "unprognostic (3.76e-2)" "unprognostic (2.77e-1)" "unprognostic (9.89e-2)" "unprognostic (6.24e-2)" "unprognostic (1.49e-2)" "potential prognostic favorable (1.13e-4)" "unprognostic (1.41e-3)" "unprognostic (4.03e-2)" "unprognostic (6.99e-2)" "unprognostic (7.21e-2)" "unprognostic (7.69e-2)" "unprognostic (1.36e-1)" "unprognostic (2.03e-1)" "unprognostic (2.48e-2)" "unprognostic (1.79e-1)" "unprognostic (2.07e-1)" "unprognostic (7.15e-2)" "unprognostic (1.69e-2)" "unprognostic (8.90e-2)" "unprognostic (7.85e-3)" "unprognostic (1.89e-2)" "unprognostic (4.01e-2)" "unprognostic (8.91e-2)" "unprognostic (2.09e-1)" "unprognostic (1.26e-1)" "unprognostic (6.20e-2)" ZCCHC9 "DKFZp761J139, PPP1R41" ENSG00000131732 "Zinc finger CCHC-type containing 9" Q8N567 5 81301587-81313297 "Essential proteins, Predicted intracellular proteins" Transcription "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038404 Uncertain Supported Nucleoplasm,Nucleoli NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 25: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 97: Non-specific - Cellular respiration" 9 Nucleoplasm Nucleoli "HPA038404: " "unprognostic (6.82e-2)" "unprognostic (7.38e-2)" "unprognostic (1.44e-1)" "unprognostic (1.91e-1)" "unprognostic (9.50e-2)" "unprognostic (6.45e-2)" "unprognostic (1.68e-3)" "unprognostic (2.80e-2)" "unprognostic (4.30e-2)" "unprognostic (5.82e-2)" "unprognostic (1.61e-3)" "unprognostic (9.91e-2)" "unprognostic (4.18e-2)" "unprognostic (1.37e-2)" "unprognostic (4.62e-2)" "unprognostic (9.06e-3)" "potential prognostic unfavorable (4.60e-4)" "unprognostic (8.62e-2)" "unprognostic (3.83e-1)" "unprognostic (2.29e-1)" "unprognostic (1.06e-2)" "unprognostic (1.06e-2)" "unprognostic (2.16e-3)" "unprognostic (1.07e-2)" "unprognostic (3.42e-2)" "unprognostic (1.40e-2)" "unprognostic (3.78e-2)" "unprognostic (1.36e-1)" "unprognostic (3.80e-1)" "unprognostic (2.17e-1)" "unprognostic (1.81e-1)" ZCRB1 "MADP-1, MADP1, RBM36, SNRNP31, ZCCHC19" ENSG00000139168 "Zinc finger CCHC-type and RNA binding motif containing 1" Q8TBF4 12 42312086-42326257 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early primary spermatocytes: 332.0;Early spermatids: 816.6;Late primary spermatocytes: 959.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 43 "unprognostic (1.58e-1)" "unprognostic (7.62e-3)" "unprognostic (2.01e-1)" "unprognostic (5.39e-2)" "unprognostic (2.13e-2)" "unprognostic (5.48e-3)" "unprognostic (1.11e-1)" "unprognostic (6.75e-2)" "potential prognostic unfavorable (7.85e-4)" "potential prognostic unfavorable (8.24e-6)" "unprognostic (4.18e-2)" "unprognostic (4.19e-3)" "unprognostic (3.09e-3)" "validated prognostic unfavorable (9.61e-9)" "validated prognostic unfavorable (8.00e-5)" "unprognostic (8.32e-3)" "unprognostic (1.86e-2)" "unprognostic (7.87e-2)" "unprognostic (1.57e-1)" "unprognostic (1.03e-2)" "unprognostic (1.15e-1)" "unprognostic (6.21e-2)" "potential prognostic unfavorable (3.31e-4)" "unprognostic (2.78e-1)" "unprognostic (2.20e-2)" "unprognostic (1.34e-1)" "unprognostic (1.09e-1)" "unprognostic (6.61e-2)" "unprognostic (2.63e-1)" "unprognostic (1.97e-2)" "unprognostic (4.71e-2)" ZCWPW1 "DKFZp434N0510, FLJ10057, ZCW1" ENSG00000078487 "Zinc finger CW-type and PWWP domain containing 1" Q9H0M4 7 100400826-100428992 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "testis: 35.8" "Cell type enriched" "Detected in many" 7 "Early primary spermatocytes: 1351.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Spleen - B-cells (Spleen), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020911 Approved "Golgi apparatus" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 57: Testis - Spermatogenesis" "Cluster 25: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 3: Early primary spermatocytes - Early meiosis" "Golgi apparatus" "HPA020911: " "unprognostic (2.10e-3)" "unprognostic (9.46e-2)" "unprognostic (1.25e-1)" "unprognostic (1.58e-1)" "unprognostic (1.18e-3)" "unprognostic (8.85e-3)" "unprognostic (5.01e-3)" "unprognostic (1.86e-1)" "unprognostic (9.54e-2)" "unprognostic (1.76e-1)" "unprognostic (2.52e-2)" "unprognostic (6.10e-3)" "unprognostic (3.10e-3)" "unprognostic (3.47e-1)" "unprognostic (1.05e-1)" "unprognostic (1.36e-1)" "unprognostic (3.04e-1)" "unprognostic (2.37e-2)" "unprognostic (4.14e-2)" "unprognostic (8.84e-2)" "unprognostic (2.45e-1)" "potential prognostic favorable (7.33e-4)" "unprognostic (4.62e-2)" "unprognostic (1.47e-2)" "unprognostic (3.16e-2)" "unprognostic (4.45e-2)" "unprognostic (4.47e-2)" "unprognostic (4.32e-1)" "unprognostic (2.68e-2)" "unprognostic (4.76e-2)" "unprognostic (7.21e-2)" ZCWPW2 ZCW2 ENSG00000206559 "Zinc finger CW-type and PWWP domain containing 2" Q504Y3 3 28348721-28538122 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 9.3" "Cell type enhanced" "Detected in many" "Astrocytes: 69.6;Bergmann glia: 54.4;Brain excitatory neurons: 47.8;Brain inhibitory neurons: 47.8;Cardiomyocytes: 77.8;Choroid plexus epithelial cells: 59.5;Early spermatids: 45.6;Ependymal cells: 57.0;Epicardial cells: 79.6;Late primary spermatocytes: 134.9;Oligodendrocyte progenitor cells: 50.9;Oligodendrocytes: 40.5;Other brain neurons: 40.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Skeletal muscle - Skeletal myocytes, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA035035, HPA039839" Uncertain Approved "Nuclear speckles" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 61: Non-specific - Transcription" "Cluster 9: Non-specific - Receptor signaling" "Cluster 27: Breast cancer - Unknown function" "Cluster 28: Astrocytes - Homeostasis & neuron support" 2 "Nuclear speckles" "HPA035035: , HPA039839: " "unprognostic (7.97e-2)" "unprognostic (4.65e-2)" "unprognostic (6.29e-2)" "unprognostic (4.56e-1)" "unprognostic (2.48e-1)" "unprognostic (2.88e-2)" "unprognostic (1.63e-1)" "unprognostic (2.56e-1)" "potential prognostic favorable (4.04e-4)" "unprognostic (7.44e-3)" "unprognostic (3.52e-1)" "unprognostic (1.63e-1)" "unprognostic (3.86e-3)" "unprognostic (2.46e-1)" "unprognostic (2.28e-2)" "unprognostic (1.34e-2)" "unprognostic (2.99e-1)" "unprognostic (2.44e-3)" "unprognostic (4.87e-2)" ZDBF2 "FLJ45338, KIAA1571" ENSG00000204186 "Zinc finger DBF-type containing 2" Q9HCK1 2 206274663-206314427 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 86.5;Brain inhibitory neurons: 117.1;Choroid plexus epithelial cells: 413.8;Ependymal cells: 52.4;Oligodendrocyte progenitor cells: 42.0;Other brain neurons: 91.5;Podocytes: 44.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 9.2" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA039121, HPA050311" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 64: Non-specific - Transcription" "Cluster 23: Choroid plexus - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 8 Nucleoplasm Cytosol "HPA039121: , HPA050311: " "unprognostic (3.75e-2)" "unprognostic (1.17e-2)" "unprognostic (4.01e-2)" "unprognostic (1.71e-1)" "potential prognostic favorable (9.67e-4)" "potential prognostic unfavorable (3.81e-4)" "unprognostic (2.68e-1)" "unprognostic (3.79e-2)" ZDHHC1 "C16orf1, HSU90653, ZNF377" ENSG00000159714 "Zinc finger DHHC-type containing 1" Q8WTX9 16 67394152-67416833 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 132.9;Endometrial ciliated cells: 107.5;Epididymal efferent duct ciliated cells: 87.3;Fallopian tube ciliated cells: 107.4;Late primary spermatocytes: 168.8;Late spermatids: 305.8;Respiratory ciliated cells: 149.7" "Cell type enhanced" "Detected in all" "ependymal cell: 64.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.4;non-classical monocyte: 1.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Lung - Respiratory ciliated cells, Spleen - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042531, HPA048659" Uncertain Approved Cytosol NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 21: Testis - Mixed function" "Cluster 17: Choroid plexus - Cilium" "Cluster 27: Breast cancer - Unknown function" "Cluster 107: Ciliated cells - Cilia assembly & function" 14 Cytosol "HPA042531: , HPA048659: " "unprognostic (1.63e-3)" "unprognostic (9.43e-2)" "unprognostic (2.78e-2)" "unprognostic (1.54e-1)" "unprognostic (4.23e-2)" "unprognostic (7.09e-3)" "unprognostic (3.58e-2)" "unprognostic (2.69e-2)" "unprognostic (1.89e-1)" "unprognostic (3.35e-3)" "unprognostic (3.72e-2)" "unprognostic (1.95e-2)" "unprognostic (2.99e-2)" "unprognostic (1.08e-1)" "unprognostic (2.69e-1)" "unprognostic (1.24e-2)" "unprognostic (2.77e-1)" "unprognostic (1.28e-1)" "unprognostic (1.11e-1)" "unprognostic (1.32e-1)" "unprognostic (3.23e-1)" "unprognostic (2.26e-3)" "unprognostic (1.05e-1)" "unprognostic (2.19e-1)" "unprognostic (1.91e-2)" "unprognostic (1.12e-1)" "unprognostic (2.07e-1)" "unprognostic (1.13e-1)" "unprognostic (9.64e-2)" "unprognostic (5.08e-2)" "unprognostic (3.29e-2)" ZDHHC11 "FLJ13153, ZNF399" ENSG00000188818 "Zinc finger DHHC-type containing 11" Q9H8X9 5 795605-858973 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 40.9;Choroid plexus epithelial cells: 71.0;Corticotrophs: 56.5;Endometrial ciliated cells: 61.2;Ependymal cells: 132.7;Lactotrophs: 73.6;Respiratory ciliated cells: 42.1;Somatotrophs: 78.4;Thyrotrophs: 98.8" "Cell type enhanced" "Detected in all" "ependymal cell: 133.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "HPA057886, HPA069008" Uncertain Uncertain "Golgi apparatus" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 48: Non-specific - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 34: Ciliated cells - Cilia assembly & function" 3 "Golgi apparatus" "HPA057886: , HPA069008: " "unprognostic (3.65e-2)" "unprognostic (7.31e-2)" "unprognostic (3.60e-1)" "unprognostic (1.82e-1)" "unprognostic (1.83e-3)" "unprognostic (1.28e-2)" "unprognostic (9.56e-3)" "unprognostic (2.65e-2)" "unprognostic (1.86e-1)" "unprognostic (2.69e-2)" "potential prognostic unfavorable (1.89e-5)" "unprognostic (1.22e-2)" "unprognostic (1.14e-1)" "unprognostic (6.07e-2)" "unprognostic (2.95e-1)" "unprognostic (1.87e-1)" "unprognostic (2.06e-1)" "unprognostic (2.06e-1)" "potential prognostic favorable (9.35e-4)" "unprognostic (2.92e-1)" "unprognostic (1.85e-2)" "unprognostic (1.66e-2)" "unprognostic (3.43e-3)" "unprognostic (1.09e-1)" "unprognostic (1.79e-1)" "unprognostic (1.99e-1)" "unprognostic (2.74e-2)" "unprognostic (2.57e-1)" "unprognostic (7.18e-2)" ZDHHC11B ENSG00000206077 "Zinc finger DHHC-type containing 11B" P0C7U3 5 710355-784729 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 35.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 86.8;Corticotrophs: 82.1;Lactotrophs: 127.3;Late primary spermatocytes: 80.2;Oligodendrocytes: 82.4;Somatotrophs: 147.4;Thyrotrophs: 224.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 2.9" "HPA057886, HPA069008" Uncertain Uncertain "Golgi apparatus" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 34: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" "Golgi apparatus" "HPA057886: , HPA069008: " "unprognostic (2.01e-2)" "unprognostic (9.38e-2)" "unprognostic (8.10e-2)" "unprognostic (1.59e-1)" "unprognostic (8.34e-3)" "unprognostic (5.72e-2)" "unprognostic (1.42e-2)" "unprognostic (6.54e-3)" "unprognostic (6.56e-2)" "potential prognostic favorable (4.38e-4)" "unprognostic (4.33e-2)" "unprognostic (1.39e-1)" "unprognostic (1.90e-2)" "unprognostic (2.48e-2)" "unprognostic (1.01e-1)" "unprognostic (2.81e-1)" "unprognostic (8.18e-2)" "unprognostic (5.82e-3)" "unprognostic (1.50e-1)" "unprognostic (2.68e-1)" "unprognostic (1.14e-1)" ZDHHC12 "FLJ14524, ZNF400" ENSG00000160446 "Zinc finger DHHC-type palmitoyltransferase 12" Q96GR4 9 128720870-128724127 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Colonocytes: 151.0;Cytotrophoblasts: 215.2;Enterocytes: 162.6;Esophageal apical cells: 228.5;Esophageal basal cells: 190.2;Esophageal suprabasal cells: 222.8;Extravillous trophoblasts: 286.1;Hofbauer cells: 151.2;Migrating cytotrophoblasts: 187.7" "Cell type enhanced" "Detected in many" "leukocyte: 13.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Spleen - Neutrophils_2, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059339 Uncertain Approved "Nucleoplasm,Intermediate filaments" No No "Cluster 22: Eosinophils - Transcription" "Cluster 60: Stomach - Digestion" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 63: Cytotrophoblasts - Basic cellular functions" Nucleoplasm "Intermediate filaments" "HPA059339: " "unprognostic (1.23e-3)" "unprognostic (1.02e-1)" "unprognostic (1.81e-1)" "unprognostic (3.69e-2)" "unprognostic (4.87e-1)" "unprognostic (6.45e-2)" "potential prognostic unfavorable (3.94e-4)" "unprognostic (4.11e-2)" "unprognostic (4.86e-2)" "unprognostic (2.46e-1)" "unprognostic (7.61e-2)" "unprognostic (1.03e-2)" "unprognostic (2.45e-2)" "unprognostic (3.31e-3)" "potential prognostic unfavorable (3.93e-5)" "unprognostic (1.82e-2)" "unprognostic (2.15e-1)" "unprognostic (7.78e-3)" "unprognostic (2.26e-1)" "unprognostic (8.18e-2)" "unprognostic (3.42e-2)" "unprognostic (2.83e-1)" "unprognostic (3.27e-1)" "unprognostic (1.42e-1)" "unprognostic (1.05e-1)" "unprognostic (1.44e-1)" "unprognostic (1.86e-2)" "unprognostic (5.26e-2)" "unprognostic (1.36e-1)" "unprognostic (3.31e-2)" "unprognostic (1.54e-1)" ZDHHC13 "FLJ10852, FLJ10941, HIP14L" ENSG00000177054 "Zinc finger DHHC-type palmitoyltransferase 13" Q8IUH4 11 19117099-19176422 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 189.3;Esophageal apical cells: 487.7;Neutrophil progenitors: 172.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Macrophages, Liver - Vascular endothelial cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016759, HPA018791" Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 3: Rhabdoid - Membrane components" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 21 Vesicles "Golgi apparatus" "HPA016759: , HPA018791: " "unprognostic (2.46e-1)" "unprognostic (1.02e-2)" "unprognostic (5.44e-2)" "unprognostic (2.76e-1)" "unprognostic (9.43e-2)" "unprognostic (1.06e-1)" "unprognostic (6.86e-3)" "unprognostic (4.70e-2)" "unprognostic (7.14e-2)" "unprognostic (8.19e-2)" "potential prognostic favorable (6.30e-6)" "unprognostic (3.16e-1)" "unprognostic (1.96e-1)" "unprognostic (2.60e-2)" "unprognostic (3.67e-2)" "unprognostic (3.88e-1)" "unprognostic (7.39e-2)" "unprognostic (2.01e-1)" "unprognostic (2.70e-1)" "unprognostic (3.89e-1)" "unprognostic (1.96e-3)" "unprognostic (1.20e-1)" "unprognostic (1.40e-2)" "unprognostic (3.89e-1)" "unprognostic (3.74e-2)" "unprognostic (3.91e-2)" "unprognostic (8.15e-2)" "unprognostic (3.66e-2)" "unprognostic (5.27e-2)" "unprognostic (1.25e-1)" "unprognostic (3.56e-1)" ZDHHC14 "FLJ20984, NEW1CP" ENSG00000175048 "Zinc finger DHHC-type palmitoyltransferase 14" Q8IZN3 6 157381133-157678157 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Bergmann glia: 603.9;Distal convoluted tubule cells: 573.8;Ependymal cells: 397.0;Erythrocyte progenitors: 404.3;Lymphatic endothelial cells: 472.8;Oligodendrocyte progenitor cells: 579.2;Retinal horizontal cells: 390.7;Sertoli cells: 395.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013437, HPA063754" Approved Uncertain Vesicles NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 27: Non-specific - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 1 Vesicles "HPA013437: , HPA063754: " "unprognostic (6.40e-2)" "unprognostic (3.74e-3)" "unprognostic (1.37e-1)" "unprognostic (1.23e-1)" "unprognostic (8.62e-2)" "unprognostic (1.97e-1)" "unprognostic (4.96e-1)" "unprognostic (1.58e-1)" "unprognostic (5.11e-2)" "unprognostic (1.92e-1)" "potential prognostic favorable (1.09e-5)" "unprognostic (2.27e-3)" "unprognostic (2.89e-1)" "unprognostic (8.52e-2)" "unprognostic (1.11e-1)" "unprognostic (1.60e-1)" "unprognostic (1.82e-1)" "unprognostic (1.90e-1)" "unprognostic (8.57e-2)" "unprognostic (4.33e-2)" "unprognostic (2.02e-2)" "unprognostic (5.09e-3)" "unprognostic (1.17e-1)" "unprognostic (2.59e-2)" "unprognostic (2.36e-1)" "unprognostic (1.53e-2)" "unprognostic (5.28e-3)" "unprognostic (3.20e-1)" "unprognostic (8.34e-2)" "unprognostic (9.55e-2)" ZDHHC15 "DHHC15, FLJ31812, MRX91" ENSG00000102383 "Zinc finger DHHC-type palmitoyltransferase 15" Q96MV8 X 75368427-75523502 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Acyltransferase, Transferase" "Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 86.0;Epicardial cells: 70.5" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 5.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 2.2;Rhabdoid: 2.3" "Adrenal gland - Adrenal cortex cells, Prostate - Fibroblasts, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003618, HPA064901" Approved Approved "Nuclear speckles,Cytosol" NA NA "Cluster 65: Brain - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 50 "Nuclear speckles" Cytosol "HPA003618: , HPA064901: " "unprognostic (1.74e-2)" "unprognostic (1.15e-1)" "unprognostic (2.45e-1)" "potential prognostic favorable (2.50e-6)" "unprognostic (1.97e-2)" "unprognostic (1.05e-1)" "unprognostic (2.69e-1)" "unprognostic (8.39e-3)" "unprognostic (1.02e-1)" ZDHHC16 APH2 ENSG00000171307 "Zinc finger DHHC-type palmitoyltransferase 16" Q969W1 10 97446170-97457370 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Apoptosis, DNA damage" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 91.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039893, HPA040214" Uncertain Uncertain "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 70: Non-specific - Protein processing" "Cluster 15: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 3 Nucleoplasm "Nuclear membrane, Cytosol" "HPA039893: , HPA040214: " "unprognostic (6.08e-2)" "unprognostic (4.99e-3)" "unprognostic (1.76e-1)" "unprognostic (8.03e-3)" "unprognostic (3.32e-1)" "unprognostic (1.17e-1)" "unprognostic (1.09e-1)" "potential prognostic favorable (8.30e-5)" "unprognostic (5.80e-3)" "unprognostic (1.71e-2)" "unprognostic (2.89e-2)" "unprognostic (7.32e-2)" "unprognostic (4.38e-1)" "unprognostic (5.69e-3)" "potential prognostic unfavorable (6.28e-4)" "unprognostic (1.32e-1)" "unprognostic (7.59e-2)" "unprognostic (8.27e-3)" "unprognostic (3.71e-2)" "unprognostic (1.67e-1)" "unprognostic (9.08e-2)" "unprognostic (2.12e-2)" "unprognostic (5.66e-3)" "unprognostic (1.16e-2)" "unprognostic (6.05e-2)" "unprognostic (2.00e-2)" "unprognostic (5.77e-2)" "unprognostic (2.28e-1)" "unprognostic (2.72e-1)" "unprognostic (5.36e-2)" "unprognostic (7.80e-2)" ZDHHC17 "HIP14, HYPH, KIAA0946" ENSG00000186908 "Zinc finger DHHC-type palmitoyltransferase 17" Q8IUH5 12 76764103-76853696 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Acyltransferase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ependymal cells: 273.2;Neutrophil progenitors: 250.8;Neutrophils: 300.8;pDCs: 268.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 17.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016807 Approved Supported "Golgi apparatus,Vesicles" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 65: Brain - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 126 "Golgi apparatus" Vesicles "HPA016807: " "unprognostic (6.29e-2)" "unprognostic (9.95e-2)" "unprognostic (2.53e-1)" "unprognostic (4.73e-2)" "unprognostic (1.20e-1)" "unprognostic (5.25e-2)" "unprognostic (3.74e-2)" "unprognostic (1.43e-1)" "unprognostic (2.77e-2)" "unprognostic (1.45e-2)" "unprognostic (2.70e-2)" "unprognostic (1.63e-3)" "unprognostic (3.32e-2)" "unprognostic (2.10e-3)" "unprognostic (2.26e-2)" "unprognostic (6.90e-2)" "unprognostic (1.07e-1)" "unprognostic (1.93e-2)" "unprognostic (1.42e-1)" "unprognostic (1.67e-2)" "unprognostic (8.07e-2)" "unprognostic (5.43e-3)" "unprognostic (5.12e-3)" "unprognostic (1.37e-1)" "unprognostic (7.74e-2)" "unprognostic (3.53e-2)" "unprognostic (1.20e-1)" "unprognostic (1.74e-2)" "unprognostic (2.92e-1)" "unprognostic (8.29e-2)" "unprognostic (1.25e-1)" ZDHHC18 DKFZp667O2416 ENSG00000204160 "Zinc finger DHHC-type palmitoyltransferase 18" Q9NUE0 1 26826688-26857604 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Immunity, Innate immunity" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 107.7" "Cell type enriched" "Detected in many" 7 "Neutrophils: 581.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "neutrophil: 49.1" "Lineage enriched" "Detected in many" 18 "granulocytes: 49.1" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040234, HPA076815" Approved Approved "Golgi apparatus,Cytosol" NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 15: Bone marrow - Innate immune response" "Cluster 1: Neurons - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 3 Cytosol "Golgi apparatus" "HPA040234: , HPA076815: " "unprognostic (1.71e-1)" "unprognostic (1.52e-1)" "unprognostic (1.44e-1)" "unprognostic (1.51e-1)" "unprognostic (5.40e-2)" "unprognostic (2.62e-1)" "potential prognostic unfavorable (7.69e-4)" "unprognostic (1.67e-1)" "unprognostic (9.10e-2)" "unprognostic (4.88e-2)" "unprognostic (2.22e-2)" "unprognostic (4.29e-2)" "unprognostic (3.00e-3)" "validated prognostic unfavorable (3.40e-6)" "validated prognostic unfavorable (7.98e-7)" "unprognostic (2.76e-2)" "unprognostic (1.79e-2)" "unprognostic (3.06e-2)" "unprognostic (1.83e-1)" "unprognostic (1.40e-3)" "unprognostic (1.77e-1)" "unprognostic (1.35e-2)" "unprognostic (1.98e-1)" "unprognostic (6.13e-2)" "unprognostic (2.97e-1)" "unprognostic (3.45e-1)" "unprognostic (1.12e-1)" "unprognostic (1.18e-1)" "unprognostic (1.67e-1)" "unprognostic (3.73e-2)" "unprognostic (4.67e-2)" ZDHHC19 MGC33345 ENSG00000163958 "Zinc finger DHHC-type palmitoyltransferase 19" Q8WVZ1 3 196197452-196211437 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 30 "testis: 47.2" "Group enriched" "Detected in some" 4 "Early spermatids: 481.7;Late spermatids: 1490.8" "Cell type enhanced" "Detected in many" "hippocampal dentate gyrus: 14.5" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 20 "eosinophil: 1.2;memory B-cell: 2.5;naive B-cell: 2.4;neutrophil: 1.5" "Group enriched" "Detected in many" 21 "B-cells: 2.5;granulocytes: 1.5" "Not detected" "Not detected" "Adrenal gland - Adrenal cortex cells, Heart muscle - Neutrophils, Lung - Neutrophils_2, Pituitary gland - Gonadotropes, Spleen - Neutrophils_2, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 79: Testis - Spermatogenesis" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 27 "unprognostic (2.37e-1)" ZDHHC2 "DHHC2, ZNF372" ENSG00000104219 "Zinc finger DHHC-type palmitoyltransferase 2" Q9UIJ5 8 17156482-17224799 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 72.0" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 236.0;Rod photoreceptor cells: 336.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023331, HPA023334" Uncertain Supported "Plasma membrane" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 42: Retina - Visual perception" "Cluster 25: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "Plasma membrane" "HPA023331: , HPA023334: " "potential prognostic favorable (2.66e-4)" "unprognostic (8.84e-2)" "unprognostic (1.33e-1)" "unprognostic (4.53e-1)" "unprognostic (5.05e-3)" "unprognostic (2.24e-1)" "unprognostic (1.85e-2)" "unprognostic (5.60e-3)" "unprognostic (1.92e-1)" "unprognostic (3.62e-2)" "unprognostic (2.33e-3)" "unprognostic (7.40e-2)" "unprognostic (3.70e-2)" "unprognostic (1.79e-1)" "unprognostic (1.40e-1)" "unprognostic (1.25e-2)" "unprognostic (9.27e-2)" "unprognostic (8.93e-2)" "unprognostic (4.76e-2)" "unprognostic (6.91e-2)" "unprognostic (2.46e-2)" "unprognostic (2.83e-2)" "unprognostic (2.51e-2)" "unprognostic (4.42e-1)" "unprognostic (1.30e-1)" "unprognostic (1.98e-2)" "unprognostic (5.78e-2)" "unprognostic (1.98e-2)" "unprognostic (4.73e-1)" "unprognostic (3.02e-2)" "unprognostic (2.78e-1)" ZDHHC20 "DHHC20, FLJ25952" ENSG00000180776 "Zinc finger DHHC-type palmitoyltransferase 20" Q5W0Z9 13 21348784-21459370 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 564.1;Neutrophils: 1413.4;Oligodendrocytes: 445.4" "Cell type enhanced" "Detected in all" "oligodendrocyte: 724.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014483, HPA014702" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 30: White matter - Myelination" "Cluster 19: Non-specific - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" 2 "Vesicles, Plasma membrane" "HPA014483: , HPA014702: " "unprognostic (5.38e-2)" "unprognostic (3.18e-1)" "unprognostic (2.62e-1)" "potential prognostic unfavorable (2.99e-4)" "unprognostic (1.36e-1)" "unprognostic (6.27e-3)" "unprognostic (1.27e-1)" "unprognostic (4.15e-2)" "unprognostic (8.90e-2)" "unprognostic (3.34e-2)" "potential prognostic favorable (1.11e-4)" "unprognostic (3.02e-3)" "unprognostic (3.98e-2)" "unprognostic (2.35e-2)" "unprognostic (2.95e-2)" "unprognostic (9.55e-2)" "unprognostic (2.85e-2)" "unprognostic (4.40e-2)" "unprognostic (1.35e-1)" "unprognostic (7.17e-3)" "potential prognostic unfavorable (6.11e-4)" "potential prognostic unfavorable (1.40e-4)" "unprognostic (1.84e-1)" "unprognostic (5.62e-2)" "unprognostic (9.01e-2)" "unprognostic (3.31e-1)" "unprognostic (9.92e-2)" "unprognostic (8.44e-2)" "unprognostic (2.71e-1)" "unprognostic (2.02e-1)" "unprognostic (5.82e-2)" ZDHHC21 "DHHC21, DNZ1, HSPC097" ENSG00000175893 "Zinc finger DHHC-type palmitoyltransferase 21" Q8IVQ6 9 14611071-14693432 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bergmann glia: 366.2;Lactotrophs: 318.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065254 Approved Approved "Golgi apparatus,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 2: Neurons - Nucleosome" "Cluster 47: Leukemia - Hemostasis" "Cluster 7: Non-specific - Transcription" 11 "Golgi apparatus, Cytosol" "HPA065254: " "unprognostic (1.08e-3)" "unprognostic (3.24e-2)" "unprognostic (6.09e-2)" "unprognostic (5.52e-2)" "unprognostic (7.77e-2)" "unprognostic (3.73e-1)" "unprognostic (1.56e-1)" "unprognostic (8.14e-2)" "unprognostic (1.81e-2)" "unprognostic (1.91e-2)" "potential prognostic favorable (9.57e-7)" "unprognostic (1.01e-2)" "unprognostic (4.74e-2)" "unprognostic (2.12e-1)" "unprognostic (3.01e-2)" "unprognostic (1.68e-1)" "unprognostic (2.05e-1)" "unprognostic (2.31e-1)" "unprognostic (2.94e-1)" "unprognostic (3.41e-2)" "unprognostic (4.67e-2)" "unprognostic (8.86e-2)" "unprognostic (6.27e-2)" "unprognostic (1.73e-3)" "unprognostic (2.34e-2)" "unprognostic (3.72e-2)" "unprognostic (1.49e-1)" "unprognostic (1.62e-1)" "unprognostic (5.49e-2)" "unprognostic (3.38e-1)" ZDHHC22 C14orf59 ENSG00000177108 "Zinc finger DHHC-type palmitoyltransferase 22" Q8N966 14 77131270-77142734 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 35.0" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 13.2;Brain inhibitory neurons: 9.7;Late spermatids: 9.1;Oligodendrocyte progenitor cells: 41.7;Oligodendrocytes: 6.2;Other brain neurons: 18.1;Retinal amacrine cells: 11.0;Retinal bipolar cells: 14.9;Retinal ganglion cells: 7.7;Thyrotrophs: 5.3" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in single" 37 "Glioblastoma Multiforme (TCGA): 15.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 8.6" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049471, HPA072213" Enhanced "Plasma membrane" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 16 "Plasma membrane" "HPA049471: , HPA072213: " "unprognostic (3.07e-1)" "unprognostic (5.99e-2)" "potential prognostic favorable (9.77e-5)" ZDHHC23 MGC42530 ENSG00000184307 "Zinc finger DHHC-type palmitoyltransferase 23" Q8IYP9 3 113947901-113965401 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 10.2" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 40.1;Epicardial cells: 36.4;Late primary spermatocytes: 40.9;Late spermatids: 60.6" "Cell type enhanced" "Detected in many" "hippocampal CA1-3: 81.2;hippocampal CA4: 80.3" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 17.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016808 Uncertain Approved Nucleoplasm NA NA "Cluster 21: Testis - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 35: Neurons - Synaptic function & neurogenesis" 30 Nucleoplasm "HPA016808: " "unprognostic (1.93e-1)" "unprognostic (1.37e-2)" "unprognostic (3.11e-1)" "unprognostic (1.04e-1)" "unprognostic (2.01e-1)" "unprognostic (1.51e-2)" "unprognostic (1.46e-1)" "unprognostic (1.07e-2)" "unprognostic (2.58e-2)" "unprognostic (1.44e-2)" "potential prognostic favorable (6.59e-4)" "unprognostic (1.30e-1)" "unprognostic (1.11e-2)" "unprognostic (4.57e-2)" "unprognostic (8.25e-2)" "unprognostic (2.15e-1)" "unprognostic (1.73e-1)" "unprognostic (3.38e-1)" "unprognostic (7.27e-2)" "unprognostic (1.75e-1)" "unprognostic (9.30e-2)" "unprognostic (5.61e-2)" "unprognostic (1.04e-1)" "unprognostic (2.12e-2)" "potential prognostic favorable (1.54e-5)" "unprognostic (4.63e-2)" "unprognostic (8.43e-3)" "unprognostic (1.13e-1)" "unprognostic (1.74e-2)" "unprognostic (1.05e-1)" ZDHHC24 ENSG00000174165 "Zinc finger DHHC-type containing 24" Q6UX98 11 66520637-66546235 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016619 Approved Approved Vesicles,Cytosol NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 46: Brainstem - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 17 "Vesicles, Cytosol" "HPA016619: " "unprognostic (1.40e-1)" "unprognostic (2.33e-1)" "unprognostic (2.25e-1)" "unprognostic (1.73e-1)" "unprognostic (1.83e-1)" "unprognostic (1.31e-1)" "unprognostic (4.53e-2)" "unprognostic (7.74e-2)" "unprognostic (1.38e-1)" "unprognostic (2.29e-2)" "unprognostic (2.59e-1)" "unprognostic (1.35e-1)" "unprognostic (1.40e-2)" "unprognostic (1.63e-2)" "unprognostic (2.97e-1)" "unprognostic (1.62e-2)" "unprognostic (6.78e-2)" "unprognostic (1.52e-1)" "unprognostic (3.67e-2)" "unprognostic (9.76e-2)" "unprognostic (1.21e-1)" "unprognostic (9.57e-3)" "unprognostic (5.88e-2)" "unprognostic (6.57e-2)" "unprognostic (3.60e-1)" "unprognostic (6.49e-2)" "unprognostic (1.82e-1)" "unprognostic (1.26e-2)" "unprognostic (2.84e-1)" "unprognostic (3.70e-1)" "unprognostic (1.87e-2)" ZDHHC3 "DHHC3, GODZ, ZNF373" ENSG00000163812 "Zinc finger DHHC-type palmitoyltransferase 3" Q9NYG2 3 44915257-44976185 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Early spermatids: 556.9;Late spermatids: 1958.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Adrenal cortex cells, Skin - Keratinocyte (other), Spleen - Endothelial cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012465, HPA016616" Approved Approved "Golgi apparatus" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 3 "Golgi apparatus" "CAB012465: , HPA016616: " "unprognostic (4.87e-3)" "unprognostic (8.23e-2)" "unprognostic (1.28e-1)" "unprognostic (1.52e-1)" "unprognostic (1.33e-2)" "unprognostic (3.82e-2)" "unprognostic (1.18e-1)" "unprognostic (6.10e-3)" "unprognostic (8.76e-3)" "unprognostic (3.99e-2)" "potential prognostic favorable (4.02e-6)" "unprognostic (1.89e-2)" "unprognostic (5.77e-2)" "potential prognostic unfavorable (1.24e-4)" "unprognostic (9.10e-3)" "unprognostic (1.36e-1)" "unprognostic (5.45e-2)" "unprognostic (1.18e-1)" "unprognostic (4.45e-3)" "unprognostic (2.78e-1)" "unprognostic (7.22e-2)" "unprognostic (2.90e-3)" "unprognostic (3.55e-1)" "unprognostic (2.37e-2)" "unprognostic (1.76e-1)" "unprognostic (5.13e-2)" "unprognostic (1.41e-1)" "unprognostic (9.04e-2)" "unprognostic (1.09e-1)" "unprognostic (1.06e-2)" "unprognostic (2.13e-1)" ZDHHC4 "FLJ10479, ZNF374" ENSG00000136247 "Zinc finger DHHC-type palmitoyltransferase 4" Q9NPG8 7 6577434-6589374 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032124 Approved NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 67: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 1 "HPA032124: " "unprognostic (1.53e-1)" "unprognostic (2.93e-2)" "unprognostic (3.13e-1)" "potential prognostic unfavorable (9.52e-4)" "unprognostic (1.52e-1)" "unprognostic (9.57e-2)" "unprognostic (3.97e-2)" "unprognostic (1.65e-3)" "unprognostic (1.96e-3)" "unprognostic (5.92e-2)" "validated prognostic favorable (1.18e-8)" "validated prognostic favorable (6.00e-4)" "unprognostic (1.52e-2)" "unprognostic (8.07e-3)" "unprognostic (4.40e-2)" "unprognostic (8.69e-2)" "unprognostic (1.09e-1)" "unprognostic (6.04e-2)" "unprognostic (4.09e-1)" "unprognostic (8.37e-2)" "potential prognostic unfavorable (6.26e-4)" "unprognostic (6.18e-2)" "unprognostic (9.34e-2)" "unprognostic (2.76e-1)" "unprognostic (7.92e-3)" "unprognostic (1.90e-1)" "unprognostic (3.01e-1)" "unprognostic (7.33e-2)" "unprognostic (3.18e-1)" "unprognostic (2.57e-2)" "unprognostic (5.21e-1)" ZDHHC5 "DHHC5, KIAA1748, ZNF375" ENSG00000156599 "Zinc finger DHHC-type palmitoyltransferase 5" Q9C0B5 11 57667747-57701182 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity, Lipid transport, Transport" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 155.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014670 Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 100: Stratified epithelial cells - Barrier functions" 8 "Nucleoplasm, Plasma membrane" "HPA014670: " "unprognostic (3.98e-1)" "unprognostic (3.93e-2)" "unprognostic (1.29e-1)" "unprognostic (3.02e-3)" "unprognostic (7.02e-2)" "unprognostic (1.10e-2)" "unprognostic (9.67e-2)" "unprognostic (4.84e-2)" "unprognostic (2.79e-2)" "unprognostic (3.32e-3)" "potential prognostic favorable (2.64e-7)" "unprognostic (4.09e-3)" "unprognostic (4.76e-1)" "unprognostic (1.05e-1)" "unprognostic (2.07e-1)" "unprognostic (9.97e-3)" "potential prognostic unfavorable (2.65e-4)" "unprognostic (2.19e-1)" "unprognostic (2.57e-1)" "unprognostic (4.95e-2)" "unprognostic (7.66e-2)" "potential prognostic unfavorable (2.06e-4)" "unprognostic (8.08e-2)" "unprognostic (9.84e-2)" "unprognostic (2.03e-2)" "unprognostic (2.53e-1)" "unprognostic (1.10e-1)" "unprognostic (2.17e-1)" "unprognostic (2.63e-1)" "unprognostic (8.02e-2)" "unprognostic (3.35e-1)" ZDHHC6 "FLJ21952, ZNF376" ENSG00000023041 "Zinc finger DHHC-type palmitoyltransferase 6" Q9H6R6 10 112424428-112447572 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Podocytes: 901.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Podocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014357 Approved NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 72: Kidney - Transmembrane transport" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 52: Non-specific - Mitochondria" "Cluster 57: Podocytes - Glomerular filtration" 2 "HPA014357: " "unprognostic (1.55e-1)" "unprognostic (1.67e-1)" "unprognostic (1.39e-1)" "unprognostic (4.52e-2)" "unprognostic (3.57e-1)" "unprognostic (1.35e-1)" "unprognostic (7.81e-2)" "unprognostic (9.73e-3)" "unprognostic (4.34e-2)" "unprognostic (3.07e-2)" "potential prognostic favorable (1.06e-7)" "unprognostic (4.47e-3)" "potential prognostic favorable (2.76e-4)" "unprognostic (2.24e-2)" "unprognostic (2.27e-1)" "unprognostic (9.41e-2)" "unprognostic (1.17e-1)" "unprognostic (3.34e-1)" "unprognostic (2.88e-2)" "unprognostic (1.10e-1)" "unprognostic (2.25e-1)" "unprognostic (3.30e-2)" "unprognostic (1.16e-2)" "unprognostic (9.81e-3)" "unprognostic (1.04e-3)" "unprognostic (8.28e-2)" "unprognostic (2.28e-2)" "unprognostic (1.08e-1)" "unprognostic (1.41e-1)" "unprognostic (1.73e-1)" "unprognostic (3.39e-1)" ZDHHC7 "DHHC7, FLJ10792, FLJ20279, SERZ-B, SERZ1, ZNF370" ENSG00000153786 "Zinc finger DHHC-type palmitoyltransferase 7" Q9NXF8 16 84974175-85011535 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019215, HPA059054, HPA059642" Uncertain Supported "Golgi apparatus" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" "Golgi apparatus" "HPA019215: , HPA059054: , HPA059642: " "unprognostic (4.26e-2)" "unprognostic (1.12e-1)" "unprognostic (4.54e-2)" "unprognostic (1.38e-2)" "unprognostic (7.24e-2)" "unprognostic (1.01e-1)" "unprognostic (3.19e-1)" "unprognostic (4.63e-2)" "unprognostic (8.89e-2)" "unprognostic (2.30e-1)" "unprognostic (1.23e-1)" "unprognostic (5.01e-2)" "potential prognostic favorable (7.19e-4)" "potential prognostic unfavorable (9.94e-5)" "unprognostic (6.92e-2)" "unprognostic (1.56e-1)" "unprognostic (3.11e-2)" "potential prognostic unfavorable (2.43e-4)" "unprognostic (1.86e-1)" "unprognostic (5.22e-3)" "unprognostic (1.43e-1)" "unprognostic (1.65e-2)" "unprognostic (3.02e-2)" "unprognostic (7.41e-2)" "unprognostic (5.05e-2)" "unprognostic (5.56e-2)" "unprognostic (1.83e-1)" "unprognostic (2.39e-1)" "unprognostic (2.74e-1)" "unprognostic (2.35e-2)" "unprognostic (1.58e-3)" ZDHHC8 "DHHC8, KIAA1292, ZNF378" ENSG00000099904 "Zinc finger DHHC-type palmitoyltransferase 8" Q9ULC8 22 20129456-20148007 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Host-virus interaction" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 56.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003422 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 41: Basophils - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 2 Cytosol Nucleoplasm "HPA003422: " "unprognostic (1.61e-1)" "unprognostic (3.51e-2)" "unprognostic (4.53e-1)" "unprognostic (1.74e-2)" "unprognostic (1.31e-1)" "unprognostic (3.91e-2)" "unprognostic (1.25e-1)" "unprognostic (2.21e-1)" "unprognostic (1.53e-1)" "unprognostic (2.41e-1)" "unprognostic (2.62e-1)" "unprognostic (1.95e-1)" "unprognostic (1.05e-2)" "unprognostic (5.47e-2)" "unprognostic (1.78e-2)" "unprognostic (1.55e-1)" "unprognostic (1.69e-1)" "unprognostic (2.52e-1)" "unprognostic (7.86e-2)" "unprognostic (1.96e-2)" "unprognostic (1.85e-1)" "unprognostic (6.19e-2)" "unprognostic (1.60e-3)" "unprognostic (1.52e-1)" "unprognostic (3.47e-3)" "potential prognostic favorable (6.45e-4)" "unprognostic (2.18e-1)" "unprognostic (1.55e-1)" "unprognostic (2.51e-1)" "unprognostic (1.36e-2)" "unprognostic (4.58e-2)" ZDHHC9 "CGI-89, CXorf11, DHHC9, ZDHHC10, ZNF379, ZNF380" ENSG00000188706 "Zinc finger DHHC-type palmitoyltransferase 9" Q9Y397 X 129803288-129843909 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Host-virus interaction" "Acyltransferase, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 217.3;Alveolar cells type 2: 155.8;Endometrial luminal cells: 106.4;Oligodendrocytes: 173.0;Pituicytes/FSCs: 224.4;Transitional alveolar cells: 129.9" "Group enriched" "Detected in all" 5 "committed oligodendrocyte precursor: 92.8;oligodendrocyte: 202.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031814 Uncertain Supported "Endoplasmic reticulum,Golgi apparatus,Cytosol" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 36: Non-specific - mRNA processing" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 3 "Endoplasmic reticulum, Golgi apparatus" Cytosol "HPA031814: " "unprognostic (4.81e-1)" "potential prognostic unfavorable (6.29e-5)" "unprognostic (1.35e-1)" "potential prognostic unfavorable (7.14e-5)" "unprognostic (2.64e-1)" "unprognostic (4.17e-3)" "unprognostic (3.83e-1)" "unprognostic (1.26e-1)" "potential prognostic unfavorable (3.59e-4)" "unprognostic (8.59e-2)" "potential prognostic favorable (1.97e-4)" "unprognostic (6.94e-2)" "unprognostic (7.92e-3)" "unprognostic (5.44e-3)" "potential prognostic unfavorable (9.19e-7)" "unprognostic (1.84e-1)" "potential prognostic unfavorable (4.60e-4)" "unprognostic (1.46e-1)" "unprognostic (2.90e-1)" "unprognostic (2.00e-3)" "unprognostic (4.92e-2)" "unprognostic (1.66e-3)" "unprognostic (5.31e-2)" "unprognostic (3.62e-2)" "unprognostic (3.30e-1)" "unprognostic (2.93e-1)" "unprognostic (3.53e-1)" "unprognostic (9.69e-3)" "unprognostic (2.42e-1)" "unprognostic (2.81e-3)" "unprognostic (3.98e-1)" ZEB1 "AREB6, BZP, FECD6, NIL-2-A, PPCD3, TCF8, ZEB, Zfhep, Zfhx1a" ENSG00000148516 "Zinc finger E-box binding homeobox 1" P37275 10 31318495-31529814 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 1976.0;Fibro-adipogenic progenitors: 1444.4;Oligodendrocyte progenitor cells: 1229.1;Thyrotrophs: 714.0" "Cell type enhanced" "Detected in all" "pericyte: 2152.7" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 36.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027524, CAB058686, CAB079943" Enhanced Supported Nucleoplasm,Nucleoli NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 30 Nucleoplasm Nucleoli "CAB058686: , CAB079943: , HPA027524: " "unprognostic (2.56e-2)" "unprognostic (1.66e-1)" "unprognostic (5.29e-1)" "unprognostic (4.03e-1)" "unprognostic (6.30e-2)" "unprognostic (1.88e-1)" "unprognostic (1.59e-2)" "unprognostic (7.67e-3)" "unprognostic (4.20e-2)" "unprognostic (6.66e-2)" "validated prognostic favorable (1.51e-5)" "validated prognostic favorable (1.08e-4)" "unprognostic (2.90e-3)" "unprognostic (1.33e-2)" "unprognostic (9.15e-3)" "unprognostic (6.50e-2)" "unprognostic (4.04e-2)" "unprognostic (1.02e-1)" "unprognostic (4.06e-1)" "unprognostic (1.43e-3)" "potential prognostic unfavorable (1.41e-4)" "unprognostic (2.58e-1)" "unprognostic (2.70e-1)" "unprognostic (2.28e-1)" "unprognostic (2.32e-1)" "unprognostic (3.42e-2)" "unprognostic (7.22e-2)" "unprognostic (2.61e-3)" "unprognostic (1.09e-1)" "unprognostic (4.47e-3)" "unprognostic (1.46e-2)" ZEB2 "KIAA0569, SIP-1, SIP1, ZFHX1B" ENSG00000169554 "Zinc finger E-box binding homeobox 2" O60315 2 144364364-144521057 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Disease variant, Epilepsy, Hirschsprung disease, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 176.9" "Cell type enhanced" "Detected in many" "cDC: 958.1;Kupffer cells: 1466.6;Macrophages: 1416.3;Mast cells: 1484.8;Megakaryocyte progenitors: 1110.0;Megakaryocyte-Erythroid progenitors: 1626.0;Microglia: 1179.6;Monocyte progenitors: 1739.7;monocytes: 3291.2;Neutrophils: 1952.2;NK-cells: 1052.3;Oligodendrocytes: 1841.2;Retinal horizontal cells: 1238.1" "Cell type enhanced" "Detected in all" "oligodendrocyte: 2287.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 66.5;skin cancer: 69.9" "Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003456 Approved Supported "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 27 "Nucleoplasm, Nucleoli" "Plasma membrane" "HPA003456: " "unprognostic (1.28e-1)" "unprognostic (6.65e-2)" "unprognostic (1.21e-1)" "unprognostic (1.06e-1)" "unprognostic (4.54e-2)" "unprognostic (2.13e-1)" "unprognostic (3.13e-1)" "unprognostic (7.97e-2)" "unprognostic (1.87e-2)" "unprognostic (5.95e-3)" "unprognostic (1.56e-2)" "unprognostic (5.49e-2)" "unprognostic (1.88e-1)" "unprognostic (1.36e-1)" "unprognostic (5.08e-2)" "unprognostic (8.41e-3)" "unprognostic (9.64e-3)" "unprognostic (3.49e-2)" "unprognostic (3.70e-3)" "unprognostic (2.07e-1)" "unprognostic (7.53e-3)" "unprognostic (1.28e-1)" "unprognostic (1.35e-1)" "unprognostic (1.59e-1)" "unprognostic (1.43e-2)" "unprognostic (3.94e-2)" "unprognostic (6.06e-2)" "unprognostic (6.89e-2)" "unprognostic (3.60e-2)" "unprognostic (2.09e-2)" "unprognostic (1.07e-1)" ZER1 "C9orf60, Hzyg, ZYG, ZYG11BL" ENSG00000160445 "Zyg-11 related cell cycle regulator" Q7Z7L7 9 128729786-128772414 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048464 Approved Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 24: Neurons - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 23 Cytosol "HPA048464: " "unprognostic (3.11e-1)" "unprognostic (3.45e-2)" "unprognostic (1.13e-1)" "unprognostic (6.44e-2)" "unprognostic (2.70e-1)" "unprognostic (7.74e-3)" "unprognostic (5.95e-2)" "potential prognostic favorable (1.07e-4)" "unprognostic (2.67e-1)" "unprognostic (1.14e-1)" "potential prognostic favorable (8.73e-8)" "unprognostic (3.82e-3)" "potential prognostic favorable (7.24e-6)" "unprognostic (6.17e-2)" "unprognostic (8.37e-2)" "unprognostic (2.20e-2)" "unprognostic (3.79e-1)" "unprognostic (1.49e-2)" "unprognostic (7.84e-2)" "unprognostic (5.38e-2)" "unprognostic (1.21e-1)" "unprognostic (1.87e-2)" "unprognostic (4.73e-1)" "unprognostic (1.41e-1)" "unprognostic (5.88e-2)" "unprognostic (1.91e-1)" "unprognostic (1.42e-1)" "unprognostic (2.68e-1)" "unprognostic (1.27e-1)" "unprognostic (2.09e-1)" "unprognostic (8.59e-3)" ZFAND1 FLJ14007 ENSG00000104231 "Zinc finger AN1-type containing 1" Q8TCF1 8 81701334-81732903 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023383 Approved Approved Centrosome,Cytosol NA NA 4100 "Cluster 33: Non-specific - ATP binding" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 40: Non-specific - Unknown function" "Cluster 15: Non-specific - Protein processing" 1 "Centrosome, Cytosol" "HPA023383: " "unprognostic (1.03e-1)" "unprognostic (4.45e-3)" "unprognostic (6.93e-2)" "unprognostic (4.06e-3)" "unprognostic (2.25e-1)" "unprognostic (3.50e-2)" "unprognostic (6.88e-2)" "unprognostic (5.40e-2)" "unprognostic (3.27e-2)" "unprognostic (8.85e-3)" "validated prognostic favorable (4.23e-7)" "validated prognostic favorable (3.64e-4)" "potential prognostic unfavorable (8.17e-4)" "unprognostic (6.59e-2)" "unprognostic (2.42e-2)" "unprognostic (1.17e-1)" "unprognostic (7.34e-2)" "unprognostic (1.17e-2)" "unprognostic (1.58e-1)" "unprognostic (9.76e-3)" "unprognostic (6.05e-2)" "unprognostic (2.51e-3)" "potential prognostic unfavorable (8.30e-4)" "unprognostic (1.15e-1)" "unprognostic (7.51e-3)" "unprognostic (4.10e-2)" "unprognostic (3.41e-3)" "unprognostic (1.04e-1)" "unprognostic (2.66e-1)" "unprognostic (1.07e-2)" "unprognostic (3.24e-1)" ZFAND2A AIRAP ENSG00000178381 "Zinc finger AN1-type containing 2A" Q8N6M9 7 1152071-1160759 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 6 "Oocytes: 3863.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019469 Approved NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 36: Brain & Liver - Signaling" "Cluster 31: Non-specific - Transcription" "Cluster 67: Non-specific - Unknown function" "Cluster 75: Non-specific - Chaperones and protein folding" 15 "HPA019469: " "unprognostic (8.60e-2)" "potential prognostic unfavorable (8.57e-4)" "unprognostic (2.70e-2)" "unprognostic (2.73e-2)" "unprognostic (5.62e-3)" "unprognostic (2.02e-2)" "unprognostic (2.07e-2)" "potential prognostic unfavorable (9.88e-4)" "unprognostic (1.21e-2)" "unprognostic (5.19e-2)" "unprognostic (4.87e-2)" "unprognostic (1.52e-1)" "unprognostic (3.36e-1)" "unprognostic (1.15e-1)" "unprognostic (1.07e-1)" "unprognostic (1.00e-2)" "potential prognostic unfavorable (1.68e-4)" "unprognostic (3.01e-1)" "unprognostic (7.42e-2)" "unprognostic (1.05e-1)" "unprognostic (3.15e-1)" "unprognostic (6.66e-2)" "unprognostic (8.32e-3)" "unprognostic (9.03e-2)" "unprognostic (3.97e-1)" "unprognostic (1.43e-1)" "unprognostic (5.11e-3)" "unprognostic (1.06e-2)" "unprognostic (2.09e-1)" "unprognostic (8.21e-2)" "unprognostic (1.12e-1)" ZFAND2B AIRAPL ENSG00000158552 "Zinc finger AN1-type containing 2B" Q8WV99 2 219195237-219209651 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 116.2;Enterocytes: 158.9;Esophageal apical cells: 290.5;Platelets: 145.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035159, HPA035160" Uncertain Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Nuclear bodies,Primary cilium,Primary cilium tip,Basal body,Cytosol" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 35: RS4;11 - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 18 "Nucleoli, Nucleoli rim" "Nucleoplasm, Nuclear bodies, Primary cilium, Primary cilium tip, Basal body, Cytosol" "HPA035159: , HPA035160: " "unprognostic (1.49e-1)" "unprognostic (3.37e-3)" "unprognostic (7.70e-2)" "unprognostic (2.06e-1)" "unprognostic (1.01e-1)" "unprognostic (1.89e-1)" "unprognostic (1.99e-1)" "unprognostic (1.29e-3)" "unprognostic (5.00e-2)" "unprognostic (5.58e-2)" "unprognostic (3.80e-3)" "unprognostic (3.27e-3)" "potential prognostic favorable (3.27e-4)" "unprognostic (2.38e-3)" "unprognostic (2.23e-2)" "unprognostic (3.97e-2)" "unprognostic (1.47e-1)" "unprognostic (1.36e-2)" "unprognostic (6.10e-2)" "unprognostic (2.65e-1)" "unprognostic (1.91e-1)" "unprognostic (4.62e-2)" "unprognostic (4.44e-1)" "unprognostic (1.35e-1)" "unprognostic (1.95e-1)" "unprognostic (2.24e-2)" "unprognostic (2.90e-1)" "unprognostic (2.25e-2)" "unprognostic (2.93e-2)" "unprognostic (1.88e-2)" "unprognostic (2.77e-1)" ZFAND3 "FLJ13222, TEX27" ENSG00000156639 "Zinc finger AN1-type containing 3" Q9H8U3 6 37819727-38154624 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 5205.3;Neutrophils: 4124.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016755 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 3 "Nucleoplasm, Vesicles" "HPA016755: " "unprognostic (7.08e-3)" "unprognostic (3.90e-2)" "unprognostic (5.64e-2)" "unprognostic (9.94e-3)" "unprognostic (5.71e-2)" "unprognostic (6.09e-2)" "unprognostic (3.16e-2)" "unprognostic (3.42e-3)" "unprognostic (6.44e-2)" "unprognostic (4.30e-1)" "potential prognostic favorable (6.09e-6)" "unprognostic (1.71e-2)" "unprognostic (1.96e-1)" "unprognostic (3.08e-2)" "unprognostic (2.70e-2)" "unprognostic (3.06e-2)" "unprognostic (2.08e-2)" "unprognostic (1.52e-1)" "unprognostic (2.22e-1)" "unprognostic (1.11e-1)" "unprognostic (6.73e-2)" "unprognostic (3.70e-2)" "unprognostic (1.99e-2)" "unprognostic (2.48e-2)" "unprognostic (2.90e-1)" "unprognostic (6.14e-2)" "unprognostic (3.08e-2)" "unprognostic (3.79e-2)" "unprognostic (2.70e-1)" "unprognostic (6.36e-2)" "unprognostic (2.71e-1)" ZFAND4 "ANUBL1, FLJ40185" ENSG00000172671 "Zinc finger AN1-type containing 4" Q86XD8 10 45615500-45672780 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 6 "testis: 35.0" "Cell type enhanced" "Detected in many" "Early spermatids: 539.7;Late primary spermatocytes: 265.8;Late spermatids: 1225.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA057543, HPA074103" Enhanced Approved "Golgi apparatus" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 57: Testis - Spermatogenesis" "Cluster 25: Non-specific - Transcription" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" "Golgi apparatus" "HPA057543: , HPA074103: " "unprognostic (4.66e-2)" "unprognostic (7.41e-3)" "unprognostic (2.49e-2)" "unprognostic (2.58e-2)" "unprognostic (6.14e-3)" "unprognostic (6.71e-2)" "unprognostic (2.33e-1)" "unprognostic (2.82e-2)" "unprognostic (3.28e-2)" "unprognostic (5.91e-2)" "unprognostic (1.87e-1)" "unprognostic (2.73e-2)" "unprognostic (5.48e-3)" "unprognostic (6.38e-2)" "unprognostic (8.86e-2)" "potential prognostic favorable (8.67e-5)" "unprognostic (1.56e-1)" "unprognostic (3.96e-2)" "potential prognostic favorable (2.02e-5)" "unprognostic (1.79e-1)" "unprognostic (1.46e-1)" "unprognostic (5.06e-2)" "unprognostic (7.32e-3)" "unprognostic (7.56e-2)" "unprognostic (2.74e-1)" "unprognostic (9.83e-2)" "unprognostic (2.48e-1)" ZFAND5 "ZA20D2, ZFAND5A, ZNF216" ENSG00000107372 "Zinc finger AN1-type containing 5" O76080 9 72351413-72365235 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 561.2" "Cell type enhanced" "Detected in all" "Epididymal basal cells: 1214.2;Esophageal apical cells: 967.0;Thymic myoid cells: 770.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018129, HPA077824" Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 103: Non-specific - Basic cellular processes" 8 Nucleoplasm "Nuclear bodies, Cytosol" "HPA018129: , HPA077824: " "unprognostic (1.95e-2)" "unprognostic (2.11e-2)" "unprognostic (2.57e-1)" "unprognostic (1.52e-1)" "unprognostic (7.33e-2)" "unprognostic (1.05e-1)" "unprognostic (1.05e-1)" "unprognostic (9.44e-2)" "unprognostic (3.21e-1)" "unprognostic (1.74e-1)" "potential prognostic favorable (8.85e-5)" "unprognostic (2.99e-3)" "unprognostic (2.02e-2)" "unprognostic (8.90e-3)" "unprognostic (7.97e-2)" "unprognostic (2.72e-1)" "unprognostic (1.53e-1)" "unprognostic (1.49e-1)" "unprognostic (1.61e-1)" "unprognostic (3.80e-2)" "unprognostic (1.86e-1)" "unprognostic (3.83e-1)" "unprognostic (2.77e-2)" "unprognostic (7.41e-2)" "unprognostic (1.79e-1)" "unprognostic (2.02e-3)" "unprognostic (2.74e-1)" "unprognostic (8.35e-2)" "unprognostic (8.94e-2)" "unprognostic (2.50e-3)" "unprognostic (1.22e-1)" ZFAND6 "AWP1, ZA20D3, ZFAND5B" ENSG00000086666 "Zinc finger AN1-type containing 6" Q6FIF0 15 80059568-80138393 "Predicted intracellular proteins" "Apoptosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 841.8;Neutrophils: 917.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034845, HPA052746, HPA077824" Uncertain Approved Nucleoplasm NA NA "Cluster 32: Basophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 6 Nucleoplasm "HPA034845: , HPA052746: , HPA077824: " "unprognostic (1.01e-1)" "unprognostic (1.09e-1)" "unprognostic (6.66e-2)" "unprognostic (7.40e-2)" "unprognostic (5.82e-2)" "unprognostic (2.34e-2)" "unprognostic (1.95e-1)" "unprognostic (2.50e-1)" "unprognostic (1.99e-1)" "unprognostic (5.28e-2)" "potential prognostic favorable (1.08e-5)" "unprognostic (5.48e-2)" "unprognostic (1.68e-2)" "unprognostic (2.35e-2)" "unprognostic (5.29e-3)" "unprognostic (7.04e-2)" "unprognostic (1.56e-1)" "unprognostic (2.22e-1)" "unprognostic (1.15e-1)" "unprognostic (1.15e-1)" "unprognostic (2.37e-1)" "unprognostic (9.00e-3)" "unprognostic (2.09e-1)" "unprognostic (4.58e-2)" "unprognostic (8.09e-2)" "unprognostic (2.20e-1)" "unprognostic (1.64e-1)" "unprognostic (9.49e-2)" "unprognostic (4.37e-1)" "unprognostic (1.72e-1)" "unprognostic (4.11e-1)" ZFAT "KIAA1485, ZFAT1, ZNF406" ENSG00000066827 "Zinc finger and AT-hook domain containing" Q9P243 8 134477788-134713049 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 29.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 315.6;Migrating cytotrophoblasts: 166.8;pDCs: 1005.6;Proximal tubule cells: 201.0;Syncytiotrophoblasts: 547.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 24 "plasmacytoid DC: 34.6" "Lineage enriched" "Detected in many" 24 "dendritic cells: 34.6" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Smooth muscle cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020989, HPA063592" Enhanced Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 23: Choroid plexus - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 1 "Nuclear bodies" Nucleoplasm "HPA020989: , HPA063592: " "potential prognostic favorable (3.97e-4)" "unprognostic (8.77e-2)" "unprognostic (2.47e-1)" "potential prognostic unfavorable (6.60e-4)" "unprognostic (3.87e-2)" "unprognostic (3.28e-1)" "unprognostic (1.08e-1)" "potential prognostic favorable (7.13e-5)" "unprognostic (2.25e-1)" "potential prognostic unfavorable (4.30e-4)" "potential prognostic favorable (1.29e-8)" "unprognostic (8.55e-3)" "unprognostic (1.91e-1)" "unprognostic (2.29e-2)" "unprognostic (5.19e-2)" "unprognostic (3.48e-2)" "unprognostic (1.29e-1)" "unprognostic (6.85e-2)" "unprognostic (6.99e-2)" "unprognostic (1.45e-1)" "unprognostic (2.86e-1)" "unprognostic (2.48e-2)" "potential prognostic unfavorable (2.89e-4)" "unprognostic (1.26e-1)" "unprognostic (3.33e-1)" "unprognostic (2.12e-1)" "unprognostic (9.55e-2)" "unprognostic (2.17e-1)" "unprognostic (2.20e-1)" "unprognostic (1.57e-1)" "unprognostic (2.60e-2)" ZFC3H1 "CCDC131, CSRC2, KIAA0546, MGC23401, PSRC2" ENSG00000133858 "Zinc finger C3H1-type containing" O60293 12 71609599-71667725 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 701.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007072, HPA007151" Enhanced Approved "Nucleoplasm,Intermediate filaments" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 39: Testis - Nuclear processes" "Cluster 16: Non-specific - Transcription" "Cluster 19: Non-specific - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 20 Nucleoplasm "Intermediate filaments" "HPA007072: , HPA007151: " "unprognostic (5.44e-2)" "unprognostic (1.53e-2)" "unprognostic (1.09e-1)" "unprognostic (3.37e-1)" "unprognostic (1.37e-2)" "unprognostic (2.24e-1)" "unprognostic (5.16e-2)" "unprognostic (3.02e-1)" "unprognostic (1.02e-1)" "potential prognostic unfavorable (2.75e-6)" "potential prognostic favorable (3.27e-4)" "unprognostic (1.77e-2)" "unprognostic (1.64e-1)" "potential prognostic unfavorable (2.42e-4)" "unprognostic (2.91e-1)" "potential prognostic unfavorable (1.48e-4)" "unprognostic (1.30e-1)" "unprognostic (1.25e-2)" "unprognostic (2.86e-1)" "unprognostic (5.01e-3)" "unprognostic (1.12e-1)" "unprognostic (4.77e-3)" "potential prognostic unfavorable (7.77e-5)" "unprognostic (1.62e-2)" "unprognostic (1.92e-2)" "unprognostic (4.70e-2)" "unprognostic (3.07e-1)" "unprognostic (8.63e-2)" "unprognostic (1.68e-1)" "unprognostic (1.30e-2)" "unprognostic (2.42e-1)" ZFHX2 "KIAA1056, KIAA1762, ZFH-5, ZNF409" ENSG00000136367 "Zinc finger homeobox 2" Q9C0A1 14 23520857-23556192 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 6.6" "Cell type enhanced" "Detected in many" "Early spermatids: 86.2;Ependymal cells: 137.0;Late primary spermatocytes: 63.2;Late spermatids: 79.8;Podocytes: 85.9;Respiratory ciliated cells: 150.6;Retinal amacrine cells: 81.0;Retinal bipolar cells: 195.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 4.5" "Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000720, HPA005146" Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center" Yes No "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 15: Non-specific - Transcription" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 2 "Nucleoli fibrillar center" Nucleoplasm "HPA000720: , HPA005146: " "potential prognostic favorable (3.01e-4)" "unprognostic (1.14e-1)" "unprognostic (3.12e-1)" "unprognostic (7.60e-2)" "unprognostic (2.87e-1)" "unprognostic (2.13e-1)" "unprognostic (2.52e-1)" "unprognostic (6.04e-2)" "unprognostic (3.57e-2)" "unprognostic (2.10e-1)" "unprognostic (6.72e-2)" "unprognostic (2.27e-1)" "unprognostic (1.88e-1)" ZFHX3 "ATBF1, C16orf47, FLJ26184, ZNF927" ENSG00000140836 "Zinc finger homeobox 3" Q15911 16 72782885-73891871 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Myogenesis, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Atrial fibrillation, Cancer-related genes, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Microglia: 1034.7;Prostatic glandular cells: 820.6;Retinal ganglion cells: 1734.4;Vascular smooth muscle cells: 1812.6" "Cell type enhanced" "Detected in all" "vascular associated smooth muscle cell: 3880.9" "Cancer enhanced" "Detected in all" "Ovary Serous Cystadenocarcinoma (TCGA): 32.1" "Region enriched" "Detected in all" 4 "cerebral cortex: 667.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA059353 Uncertain Supported Nucleoplasm NA NA 210000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 50: Lymphoma - Unknown function" "Cluster 62: Smooth muscle cells - Muscle contraction" 4 Nucleoplasm "HPA059353: " "unprognostic (5.84e-3)" "potential prognostic unfavorable (1.24e-4)" "unprognostic (3.72e-2)" "unprognostic (9.41e-2)" "unprognostic (1.23e-1)" "unprognostic (3.83e-2)" "unprognostic (3.58e-2)" "unprognostic (2.08e-1)" "unprognostic (3.07e-1)" "unprognostic (2.01e-1)" "validated prognostic favorable (3.04e-6)" "validated prognostic favorable (1.04e-4)" "unprognostic (1.77e-1)" "unprognostic (5.59e-2)" "unprognostic (5.98e-2)" "unprognostic (1.36e-1)" "unprognostic (1.91e-1)" "unprognostic (2.13e-1)" "unprognostic (1.57e-2)" "unprognostic (1.17e-1)" "unprognostic (4.20e-2)" "unprognostic (8.02e-2)" "potential prognostic unfavorable (2.51e-4)" "unprognostic (2.72e-2)" "unprognostic (3.78e-1)" "unprognostic (2.46e-2)" "unprognostic (2.67e-2)" "unprognostic (5.88e-2)" "unprognostic (1.56e-1)" "unprognostic (3.30e-2)" "unprognostic (1.71e-2)" ZFHX4 "FLJ20980, ZFH4" ENSG00000091656 "Zinc finger homeobox 4" Q86UP3 8 76681239-76867281 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 288.3;Adrenal medulla cells: 191.5;Astrocytes: 406.4;Corticotrophs: 385.1;Ependymal cells: 278.8;Fibro-adipogenic progenitors: 257.1;Myonuclei: 213.6;Myosatellite cells: 180.5;Oligodendrocyte progenitor cells: 281.2;Oligodendrocytes: 228.2;Pituitary stem cells: 475.8;Somatotrophs: 205.4;Thyrotrophs: 214.1" "Cell type enhanced" "Detected in many" "midbrain-derived inhibitory: 455.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Kidney - Fibroblasts, Minor Salivary Gland - Fibroblasts, Pancreas - Fibroblasts, Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA023837 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA 3300000 "Cluster 67: Testis - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 7: Non-specific - Transcription" 5 "Nucleoplasm, Nucleoli fibrillar center" "HPA023837: " "unprognostic (4.10e-1)" "unprognostic (1.38e-1)" "unprognostic (2.49e-1)" "unprognostic (8.77e-2)" "unprognostic (3.80e-1)" "unprognostic (8.21e-2)" "unprognostic (3.32e-3)" "unprognostic (1.18e-1)" "unprognostic (1.01e-1)" "unprognostic (4.21e-2)" "unprognostic (4.18e-3)" "unprognostic (2.71e-1)" ZFP1 "FLJ34243, ZNF475" ENSG00000184517 "ZFP1 zinc finger protein" Q6P2D0 16 75148494-75172236 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 18.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Prostate - Fibroblasts, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044916, HPA062910" Uncertain Approved Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 36: Brain & Liver - Signaling" "Cluster 34: Non-specific - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 98: Neurons - Neurotransmission & signaling" 26 Nucleoplasm "HPA044916: , HPA062910: " "unprognostic (1.66e-1)" "unprognostic (5.01e-2)" "unprognostic (2.40e-2)" "unprognostic (2.16e-2)" "unprognostic (1.84e-1)" "unprognostic (1.67e-1)" "unprognostic (1.10e-2)" "unprognostic (2.15e-2)" "unprognostic (6.63e-2)" "unprognostic (4.61e-2)" "potential prognostic favorable (1.03e-8)" "unprognostic (2.36e-3)" "unprognostic (7.93e-2)" "unprognostic (1.75e-1)" "potential prognostic favorable (7.85e-4)" "unprognostic (1.71e-1)" "unprognostic (2.41e-1)" "unprognostic (1.86e-3)" "unprognostic (2.67e-1)" "unprognostic (6.26e-2)" "unprognostic (3.82e-3)" "unprognostic (2.31e-1)" "unprognostic (1.95e-2)" "unprognostic (7.56e-2)" "unprognostic (1.86e-2)" "unprognostic (3.69e-1)" "unprognostic (2.24e-1)" "unprognostic (1.08e-2)" "unprognostic (3.10e-1)" "unprognostic (6.94e-2)" "unprognostic (1.95e-1)" ZFP14 "KIAA1559, ZNF531" ENSG00000142065 "ZFP14 zinc finger protein" Q9HCL3 19 36334453-36379201 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 100.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030637 Uncertain Approved "Nuclear speckles" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 65: Brain - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 1 "Nuclear speckles" "HPA030637: " "potential prognostic favorable (1.04e-4)" "unprognostic (1.90e-2)" "unprognostic (5.75e-2)" "unprognostic (2.65e-1)" "unprognostic (3.08e-1)" "unprognostic (8.09e-2)" "unprognostic (1.40e-1)" "unprognostic (1.79e-1)" "unprognostic (2.05e-3)" "unprognostic (5.11e-2)" "potential prognostic favorable (4.88e-4)" "unprognostic (3.28e-3)" "unprognostic (4.26e-2)" "unprognostic (2.71e-2)" "unprognostic (1.39e-1)" "unprognostic (1.28e-1)" "unprognostic (3.62e-2)" "unprognostic (4.81e-2)" "unprognostic (6.01e-2)" "unprognostic (2.11e-1)" "unprognostic (2.95e-2)" "unprognostic (4.51e-3)" "unprognostic (1.93e-2)" "unprognostic (3.23e-1)" "unprognostic (2.75e-3)" "unprognostic (1.55e-3)" "unprognostic (4.62e-3)" "unprognostic (1.48e-1)" "unprognostic (1.62e-1)" "unprognostic (5.16e-2)" "unprognostic (6.10e-2)" ZFP2 "FLJ21628, ZNF751" ENSG00000198939 "ZFP2 zinc finger protein" Q6ZN57 5 178895898-178933212 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bergmann glia: 30.4;Oligodendrocyte progenitor cells: 29.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023364 Uncertain NA NA "Cluster 24: Non-specific - Transcription" "Cluster 65: Brain - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 10 "HPA023364: " "unprognostic (1.18e-1)" "unprognostic (2.65e-2)" "unprognostic (5.91e-2)" "unprognostic (1.03e-2)" "unprognostic (1.38e-1)" "unprognostic (4.07e-2)" "unprognostic (3.97e-1)" "validated prognostic favorable (9.23e-5)" "validated prognostic favorable (6.84e-5)" "unprognostic (1.29e-3)" "unprognostic (1.30e-1)" "unprognostic (1.62e-1)" "unprognostic (1.57e-1)" "unprognostic (2.46e-3)" "unprognostic (1.57e-1)" "unprognostic (3.90e-1)" "unprognostic (6.65e-2)" "unprognostic (9.56e-3)" "unprognostic (1.33e-1)" "unprognostic (2.62e-1)" ZFP28 "KIAA1431, mkr5" ENSG00000196867 "ZFP28 zinc finger protein" Q8NHY6 19 56538948-56556808 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 31.9;Cardiomyocytes: 23.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028879 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 65: Brain - Transcription" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" Nucleoplasm Cytosol "HPA028879: " "unprognostic (2.94e-3)" "unprognostic (2.33e-2)" "unprognostic (1.18e-2)" "unprognostic (1.17e-2)" "unprognostic (7.84e-2)" "unprognostic (2.85e-1)" "unprognostic (3.64e-2)" "unprognostic (4.78e-2)" "validated prognostic favorable (8.04e-4)" "validated prognostic favorable (2.50e-5)" "unprognostic (1.51e-1)" "unprognostic (2.77e-2)" "unprognostic (3.76e-2)" "unprognostic (5.34e-3)" "unprognostic (1.48e-1)" "unprognostic (2.96e-1)" "unprognostic (1.97e-1)" "potential prognostic favorable (6.93e-5)" "unprognostic (2.98e-1)" "unprognostic (1.48e-2)" "unprognostic (3.14e-2)" "unprognostic (8.57e-2)" "unprognostic (3.80e-2)" "unprognostic (1.17e-2)" "unprognostic (1.56e-1)" "unprognostic (3.35e-2)" "unprognostic (1.51e-1)" ZFP3 "FLJ30726, ZNF752" ENSG00000180787 "ZFP3 zinc finger protein" Q96NJ6 17 5078467-5096374 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 31.4;Choroid plexus epithelial cells: 20.7;Myonuclei: 24.7;Respiratory ciliated cells: 26.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA053085, HPA057290" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 52: Non-specific - Cellular respiration" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 7: Liver cancer - Metabolism" "Cluster 55: Myocytes - Oxidative muscle function" 1 "Nucleoplasm, Cytosol" "HPA053085: , HPA057290: " "unprognostic (2.45e-3)" "unprognostic (6.49e-3)" "unprognostic (8.87e-2)" "unprognostic (2.71e-1)" "unprognostic (2.74e-1)" "unprognostic (2.70e-3)" "unprognostic (1.61e-1)" "unprognostic (1.02e-1)" "unprognostic (2.29e-3)" "unprognostic (3.96e-2)" "potential prognostic favorable (1.19e-7)" "unprognostic (1.07e-3)" "potential prognostic favorable (4.92e-4)" "unprognostic (3.03e-1)" "potential prognostic favorable (3.85e-4)" "unprognostic (7.53e-3)" "unprognostic (2.28e-1)" "unprognostic (3.49e-3)" "unprognostic (1.26e-1)" "unprognostic (2.46e-1)" "potential prognostic favorable (2.16e-4)" "unprognostic (2.99e-2)" "unprognostic (1.03e-1)" "unprognostic (1.15e-2)" "unprognostic (5.34e-2)" "unprognostic (3.93e-2)" "unprognostic (1.80e-1)" "unprognostic (1.98e-1)" "unprognostic (1.10e-1)" "unprognostic (3.39e-2)" ZFP30 "KIAA0961, ZNF745" ENSG00000120784 "ZFP30 zinc finger protein" Q9Y2G7 19 37613749-37692337 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 131.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030606 Uncertain Approved Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 2: Neurons - Nucleosome" "Cluster 4: Non-specific - Transcription" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 1 Cytosol "HPA030606: " "unprognostic (8.27e-3)" "unprognostic (3.39e-2)" "unprognostic (8.80e-2)" "unprognostic (1.43e-1)" "unprognostic (1.32e-2)" "unprognostic (2.18e-2)" "unprognostic (1.06e-1)" "unprognostic (3.63e-3)" "unprognostic (2.39e-3)" "unprognostic (1.49e-2)" "potential prognostic favorable (5.56e-6)" "unprognostic (1.82e-3)" "unprognostic (1.48e-2)" "unprognostic (1.99e-2)" "unprognostic (1.53e-1)" "unprognostic (5.34e-2)" "unprognostic (2.24e-1)" "unprognostic (3.22e-2)" "unprognostic (3.93e-2)" "unprognostic (5.13e-1)" "unprognostic (2.12e-2)" "unprognostic (3.88e-2)" "unprognostic (8.06e-2)" "unprognostic (1.26e-2)" "potential prognostic favorable (2.59e-4)" "unprognostic (2.44e-1)" "unprognostic (8.07e-3)" "unprognostic (1.27e-1)" "unprognostic (1.59e-1)" "unprognostic (6.07e-2)" "unprognostic (6.55e-2)" ZFP36 "G0S24, NUP475, RNF162A, TIS11, TTP" ENSG00000128016 "ZFP36 ring finger protein" P26651 19 39406847-39409412 "Predicted intracellular proteins" "Host-virus interaction, mRNA transport, RNA-mediated gene silencing, Transport" "DNA-binding, Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 4942.2;Epididymal basal cells: 3050.2;Esophageal apical cells: 4461.4;Neutrophils: 2521.3;Ovarian stromal cells: 2956.5" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 134.0;endothelial cell: 227.9;leukocyte: 109.7;vascular associated smooth muscle cell: 150.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 314.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Neutrophils" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "spinal cord: 196.4" HPA006009 Approved Approved "Intermediate filaments" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 8: Immune cells - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 31 "Intermediate filaments" "HPA006009: " "unprognostic (1.61e-2)" "unprognostic (6.61e-2)" "unprognostic (1.56e-2)" "unprognostic (1.44e-1)" "unprognostic (7.47e-2)" "unprognostic (1.09e-1)" "unprognostic (1.70e-2)" "unprognostic (7.24e-2)" "unprognostic (1.51e-1)" "potential prognostic favorable (8.64e-6)" "unprognostic (5.85e-2)" "unprognostic (6.45e-3)" "unprognostic (2.29e-2)" "unprognostic (3.57e-1)" "unprognostic (1.58e-2)" "unprognostic (2.00e-1)" "unprognostic (2.75e-1)" "unprognostic (1.10e-2)" "unprognostic (2.40e-1)" "unprognostic (1.64e-3)" "unprognostic (5.57e-2)" "unprognostic (9.34e-2)" "unprognostic (2.09e-3)" "unprognostic (2.91e-1)" "unprognostic (1.48e-1)" "unprognostic (3.30e-3)" "unprognostic (5.44e-1)" "unprognostic (2.03e-2)" "unprognostic (7.57e-2)" "unprognostic (4.97e-2)" "unprognostic (9.80e-2)" ZFP36L1 "Berg36, BRF1, cMG1, ERF1, RNF162B, TIS11B" ENSG00000185650 "ZFP36 ring finger protein like 1" Q07352 14 68787660-68796253 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA transport, Transport" "Developmental protein, DNA-binding, Ribonucleoprotein, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal basal cells: 1662.3;Epididymal efferent duct absorptive cells: 1949.5;Ocular epithelial cells: 2410.9;Prostatic club cells: 2355.0;Suprabasal keratinocytes: 2237.5" "Cell type enhanced" "Detected in many" "astrocyte: 449.5;central nervous system macrophage: 817.1;ependymal cell: 492.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 6 "neutrophil: 2922.0" "Lineage enriched" "Detected in all" 6 "granulocytes: 2922.0" "Low cancer specificity" "Detected in all" "Heart muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001301 Uncertain NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 75: Ovary - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 100: Stratified epithelial cells - Barrier functions" 12 "HPA001301: " "unprognostic (1.10e-3)" "unprognostic (7.27e-2)" "unprognostic (7.38e-2)" "unprognostic (4.84e-2)" "unprognostic (1.69e-1)" "unprognostic (2.06e-1)" "unprognostic (6.28e-2)" "unprognostic (8.80e-3)" "unprognostic (1.19e-1)" "unprognostic (2.44e-1)" "unprognostic (5.70e-2)" "unprognostic (2.09e-1)" "unprognostic (4.44e-2)" "unprognostic (1.81e-2)" "unprognostic (1.01e-1)" "unprognostic (2.59e-1)" "unprognostic (1.71e-3)" "unprognostic (5.97e-2)" "unprognostic (7.61e-3)" "potential prognostic unfavorable (1.75e-4)" "unprognostic (4.31e-2)" "unprognostic (4.43e-3)" "unprognostic (1.79e-2)" "unprognostic (1.59e-1)" "unprognostic (4.24e-2)" "unprognostic (1.12e-2)" "unprognostic (7.45e-2)" "unprognostic (8.88e-3)" "unprognostic (1.69e-1)" "unprognostic (2.38e-1)" "unprognostic (1.66e-1)" ZFP36L2 "BRF2, ERF2, RNF162C, TIS11D" ENSG00000152518 "ZFP36 ring finger protein like 2" P47974 2 43222402-43226606 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Developmental protein, Ribonucleoprotein, RNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 1314.4;Epididymal basal cells: 1552.9;Hematopoietic stem cells: 1271.8;Innate lymphoid cells: 1799.0;T-cells: 1566.7" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 826.6;leukocyte: 348.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047428 Approved NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 44: Non-specific - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 9: T-cells - Adaptive immunity: Regulation" 16 "HPA047428: " "potential prognostic favorable (1.42e-4)" "unprognostic (1.28e-2)" "unprognostic (1.92e-1)" "unprognostic (8.67e-3)" "unprognostic (3.53e-2)" "unprognostic (1.44e-2)" "unprognostic (9.41e-2)" "unprognostic (2.62e-3)" "unprognostic (2.21e-1)" "unprognostic (3.39e-1)" "potential prognostic favorable (1.76e-5)" "unprognostic (1.72e-2)" "unprognostic (1.30e-1)" "unprognostic (8.00e-2)" "unprognostic (1.29e-1)" "unprognostic (1.52e-2)" "unprognostic (7.67e-2)" "unprognostic (6.09e-3)" "unprognostic (2.23e-1)" "unprognostic (3.19e-2)" "unprognostic (3.07e-2)" "unprognostic (2.15e-2)" "unprognostic (1.07e-1)" "unprognostic (2.56e-1)" "unprognostic (4.74e-2)" "unprognostic (1.36e-2)" "unprognostic (7.69e-2)" "unprognostic (1.48e-1)" "unprognostic (4.05e-1)" "unprognostic (1.77e-1)" "unprognostic (3.01e-2)" ZFP37 ZNF906 ENSG00000136866 "ZFP37 zinc finger protein" Q9Y6Q3 9 113038377-113056759 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Lactotrophs: 39.4;Oligodendrocyte progenitor cells: 26.1;Retinal amacrine cells: 26.7;Retinal bipolar cells: 38.2;Retinal pigment epithelial cells: 25.6;Somatotrophs: 32.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 2.4" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" HPA049112 Uncertain Approved Nucleoplasm,Vesicles Yes No "Cluster 43: Non-specific - Transcription & Translation" "Cluster 65: Brain - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" Nucleoplasm Vesicles "HPA049112: " "unprognostic (1.57e-2)" "unprognostic (1.37e-1)" "unprognostic (2.23e-1)" "unprognostic (1.13e-2)" "unprognostic (3.52e-1)" "unprognostic (2.66e-2)" "unprognostic (9.89e-3)" "unprognostic (1.69e-1)" "validated prognostic favorable (2.55e-5)" "validated prognostic favorable (2.73e-4)" "unprognostic (1.38e-1)" "unprognostic (8.06e-2)" "unprognostic (2.50e-1)" "unprognostic (1.31e-1)" "unprognostic (4.72e-2)" "unprognostic (2.91e-1)" "unprognostic (4.80e-2)" "unprognostic (2.54e-1)" "unprognostic (1.04e-1)" "unprognostic (1.18e-1)" "unprognostic (4.49e-3)" "unprognostic (7.31e-2)" "unprognostic (4.01e-1)" "unprognostic (2.34e-2)" "unprognostic (1.87e-1)" "unprognostic (1.87e-1)" "unprognostic (1.47e-1)" ZFP41 "FLJ00028, FLJ38705, ZNF753" ENSG00000181638 "ZFP41 zinc finger protein" Q8N8Y5 8 143246821-143262705 "Predicted intracellular proteins" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 6.3;Bergmann glia: 6.0;Brain excitatory neurons: 5.1;Brain inhibitory neurons: 4.8;Choroid plexus epithelial cells: 10.3;Ependymal cells: 11.5;Microglia: 6.3;Oligodendrocyte progenitor cells: 4.0;Oligodendrocytes: 7.6;Other brain neurons: 5.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047232, HPA056268" Uncertain Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Plasma membrane" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 64: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 40: Non-specific - Unknown function" "Cluster 22: Non-specific - Basic cellular functions" 7 "Nucleoli, Nucleoli rim" "Nucleoplasm, Plasma membrane" "HPA047232: , HPA056268: " "unprognostic (5.07e-2)" "unprognostic (3.54e-2)" "unprognostic (6.98e-3)" "unprognostic (2.02e-2)" "unprognostic (1.18e-2)" "unprognostic (1.26e-1)" "unprognostic (2.92e-1)" "unprognostic (6.93e-2)" "unprognostic (1.22e-1)" "unprognostic (2.09e-2)" "unprognostic (2.62e-3)" "unprognostic (2.60e-2)" "unprognostic (1.56e-1)" "potential prognostic unfavorable (7.42e-4)" "unprognostic (3.85e-2)" "unprognostic (1.33e-1)" "unprognostic (7.16e-2)" "unprognostic (5.72e-2)" "unprognostic (7.54e-3)" "unprognostic (1.27e-1)" "unprognostic (9.45e-2)" "unprognostic (8.52e-3)" "unprognostic (3.81e-3)" "unprognostic (1.26e-1)" "unprognostic (1.31e-1)" "unprognostic (1.01e-1)" "unprognostic (5.14e-2)" "unprognostic (7.59e-2)" "unprognostic (1.92e-1)" "potential prognostic unfavorable (4.34e-4)" "unprognostic (2.93e-1)" ZFP42 "REX1, ZNF754" ENSG00000179059 "ZFP42 zinc finger protein" Q96MM3 4 187995771-188005046 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "testis: 2.0" "Group enriched" "Detected in some" 4 "Early spermatids: 75.1;Extravillous trophoblasts: 73.2;Migrating cytotrophoblasts: 36.8" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 15 "Testicular Germ Cell Tumor (TCGA): 121.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in many" 16 "testis cancer: 71.0" "Adipose visceral - Mesothelial cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" CAB025557 Uncertain NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 47: Testis - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 3 "CAB025557: " "unprognostic (2.06e-1)" "unprognostic (2.37e-1)" "unprognostic (8.25e-2)" "unprognostic (2.25e-1)" "potential prognostic unfavorable (3.63e-4)" "unprognostic (3.09e-1)" "unprognostic (1.63e-2)" "unprognostic (2.47e-1)" "unprognostic (7.12e-2)" "unprognostic (2.04e-2)" "unprognostic (1.88e-1)" "unprognostic (6.33e-3)" ZFP57 "bA145L22, bA145L22.2, C6orf40, ZNF698" ENSG00000204644 "ZFP57 zinc finger protein" Q9NU63 6 29672483-29681155 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 17.6;heart muscle: 8.3" "Group enriched" "Detected in some" 4 "Oligodendrocytes: 4.2;Renal collecting duct intercalated cells: 10.5" "Group enriched" "Detected in some" 8 "central nervous system macrophage: 1.6;committed oligodendrocyte precursor: 3.4;leukocyte: 5.6;oligodendrocyte: 5.2;oligodendrocyte precursor cell: 1.6;pericyte: 1.6" "Cancer enriched" "Detected in many" 6 "Testicular Germ Cell Tumor (TCGA): 15.0" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 5 "basophil: 11.3" "Lineage enriched" "Detected in many" 5 "granulocytes: 11.3" "Cancer enriched" "Detected in some" 5 "testis cancer: 11.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 34: Testis cancer - Unknown function" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 1 "unprognostic (6.52e-2)" "unprognostic (1.01e-1)" "unprognostic (7.02e-2)" "unprognostic (1.01e-2)" "unprognostic (2.76e-1)" "unprognostic (5.70e-2)" "unprognostic (2.20e-3)" "unprognostic (2.43e-2)" "unprognostic (6.12e-1)" "unprognostic (4.51e-2)" ZFP62 "FLJ34231, ZET, ZNF755" ENSG00000196670 "ZFP62 zinc finger protein" Q8NB50 5 180847611-180861285 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 56.8;Oocytes: 69.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048629 Approved Approved "Nucleoplasm,Actin filaments" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 61: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" 4 Nucleoplasm "Actin filaments" "HPA048629: " "unprognostic (3.26e-2)" "unprognostic (7.96e-2)" "unprognostic (3.49e-1)" "unprognostic (1.55e-2)" "unprognostic (5.09e-2)" "unprognostic (2.21e-1)" "unprognostic (4.06e-2)" "unprognostic (9.30e-3)" "unprognostic (6.49e-2)" "unprognostic (8.22e-3)" "potential prognostic favorable (1.46e-5)" "unprognostic (1.34e-2)" "unprognostic (1.77e-1)" "unprognostic (3.03e-1)" "unprognostic (6.90e-2)" "unprognostic (1.51e-1)" "unprognostic (1.91e-1)" "unprognostic (1.80e-1)" "unprognostic (1.56e-1)" "unprognostic (6.34e-2)" "unprognostic (9.55e-3)" "unprognostic (9.41e-2)" "unprognostic (1.55e-1)" "unprognostic (3.33e-2)" "unprognostic (3.47e-3)" "unprognostic (7.77e-3)" "unprognostic (2.42e-2)" "unprognostic (2.37e-1)" "unprognostic (1.57e-1)" "unprognostic (5.59e-2)" "unprognostic (2.89e-1)" ZFP64 "dJ548G19.1, dJ831D17.1, FLJ10734, FLJ12628, ZNF338" ENSG00000020256 "ZFP64 zinc finger protein" Q9NTW7 20 52051663-52204308 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 124.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035112, HPA058387" Uncertain Approved Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 58: Skin - Keratinization" "Cluster 9: Non-specific - Receptor signaling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 20 Nucleoplasm "HPA035112: , HPA058387: " "unprognostic (2.81e-1)" "unprognostic (3.27e-2)" "unprognostic (1.50e-1)" "unprognostic (1.44e-2)" "unprognostic (1.49e-1)" "unprognostic (1.23e-1)" "unprognostic (2.91e-1)" "unprognostic (7.85e-2)" "unprognostic (6.02e-2)" "unprognostic (5.94e-2)" "unprognostic (1.24e-3)" "unprognostic (4.88e-2)" "unprognostic (2.60e-2)" "potential prognostic unfavorable (3.43e-6)" "unprognostic (4.74e-2)" "unprognostic (5.51e-3)" "unprognostic (2.28e-3)" "unprognostic (2.28e-1)" "unprognostic (5.51e-2)" "unprognostic (1.26e-1)" "unprognostic (1.33e-2)" "unprognostic (1.98e-2)" "unprognostic (1.41e-1)" "unprognostic (1.35e-1)" "unprognostic (3.79e-3)" "unprognostic (1.63e-2)" "unprognostic (2.76e-1)" "unprognostic (1.33e-2)" "unprognostic (1.12e-1)" "unprognostic (6.49e-3)" "unprognostic (1.45e-1)" ZFP69 "FLJ16030, ZFP69A, ZKSCAN23A, ZNF642, ZSCAN54A" ENSG00000187815 "ZFP69 zinc finger protein" Q49AA0 1 40477290-40496343 "Predicted intracellular proteins, Transcription factors" "Lipid metabolism, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Cardiomyocytes: 73.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 1.9" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "HPA027808, HPA054942" Uncertain Approved Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" Nucleoplasm "HPA027808: , HPA054942: " "unprognostic (1.19e-1)" "unprognostic (1.15e-1)" "unprognostic (4.95e-1)" "unprognostic (5.75e-3)" "unprognostic (3.14e-1)" "unprognostic (3.41e-1)" "potential prognostic favorable (7.91e-5)" "potential prognostic favorable (5.45e-4)" "unprognostic (5.55e-2)" "unprognostic (4.07e-1)" "unprognostic (1.06e-1)" "unprognostic (7.77e-3)" "unprognostic (1.71e-3)" "unprognostic (2.74e-1)" "unprognostic (4.09e-1)" "unprognostic (1.69e-1)" "unprognostic (8.07e-2)" "unprognostic (1.24e-2)" "unprognostic (1.53e-1)" "unprognostic (1.77e-1)" "unprognostic (2.48e-1)" "unprognostic (1.33e-1)" "unprognostic (6.13e-2)" "unprognostic (2.24e-2)" "unprognostic (4.59e-2)" "unprognostic (6.86e-2)" "unprognostic (8.50e-2)" "unprognostic (4.96e-2)" "unprognostic (9.46e-3)" ZFP69B "FLJ34293, ZKSCAN23B, ZNF643, ZSCAN54B" ENSG00000187801 "ZFP69 zinc finger protein B" Q9UJL9 1 40450102-40463718 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 9.1;Brain inhibitory neurons: 12.5;Differentiating spermatogonia: 8.1;Hepatic stellate cells: 6.5;Neutrophils: 7.8;Oligodendrocyte progenitor cells: 8.3;Other brain neurons: 6.9;Plasma cells: 7.3;Retinal amacrine cells: 7.0;Thymocytes: 6.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" HPA044289 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 53: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 35: Neurons - Synaptic function & neurogenesis" 2 Nucleoplasm Cytosol "HPA044289: " "unprognostic (2.26e-1)" "unprognostic (7.99e-2)" "potential prognostic unfavorable (5.03e-5)" "unprognostic (4.77e-2)" "unprognostic (1.15e-2)" "unprognostic (2.03e-1)" "unprognostic (1.02e-3)" "unprognostic (3.05e-2)" "unprognostic (1.24e-1)" "unprognostic (9.16e-2)" "unprognostic (1.01e-1)" "unprognostic (2.95e-1)" "unprognostic (4.98e-2)" "unprognostic (3.14e-2)" "unprognostic (3.56e-2)" "unprognostic (2.38e-3)" "unprognostic (2.98e-1)" "unprognostic (1.85e-3)" "unprognostic (1.33e-2)" "unprognostic (1.05e-1)" "unprognostic (8.91e-2)" "unprognostic (1.55e-1)" "unprognostic (5.34e-2)" "unprognostic (2.61e-1)" ZFP82 "KIAA1948, MGC45380, ZNF545" ENSG00000181007 "ZFP82 zinc finger protein" Q8N141 19 36383120-36418644 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051669, HPA060470" Uncertain Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 65: Brain - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 1 "Nucleoplasm, Cytosol" "Nuclear membrane" "HPA051669: , HPA060470: " "unprognostic (6.55e-2)" "unprognostic (1.11e-1)" "unprognostic (4.75e-1)" "unprognostic (1.08e-1)" "unprognostic (3.73e-2)" "unprognostic (1.16e-1)" "unprognostic (3.09e-1)" "unprognostic (2.68e-2)" "unprognostic (2.01e-3)" "unprognostic (3.04e-3)" "unprognostic (1.47e-1)" "unprognostic (8.92e-2)" "unprognostic (3.20e-1)" "unprognostic (5.33e-2)" "unprognostic (3.75e-1)" "unprognostic (9.71e-2)" "unprognostic (8.11e-2)" "unprognostic (1.03e-1)" "unprognostic (1.04e-3)" "unprognostic (3.77e-2)" "unprognostic (1.37e-1)" "unprognostic (1.43e-2)" "unprognostic (2.84e-1)" "unprognostic (5.58e-2)" "unprognostic (5.39e-2)" "unprognostic (9.34e-3)" "unprognostic (3.70e-3)" ZFP90 "KIAA1954, NK10, ZNF756" ENSG00000184939 "ZFP90 zinc finger protein" Q8TF47 16 68530090-68576072 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029017 Uncertain Supported "Vesicles,Plasma membrane,Centrosome" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 65: Brain - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Transcription" 24 "Vesicles, Plasma membrane, Centrosome" "HPA029017: " "unprognostic (1.60e-1)" "unprognostic (2.67e-1)" "unprognostic (6.87e-2)" "unprognostic (1.22e-1)" "unprognostic (2.09e-1)" "unprognostic (3.24e-1)" "unprognostic (2.08e-1)" "unprognostic (1.29e-1)" "unprognostic (2.58e-1)" "unprognostic (6.02e-2)" "unprognostic (7.29e-3)" "unprognostic (1.13e-1)" "potential prognostic favorable (6.03e-4)" "potential prognostic unfavorable (8.74e-4)" "unprognostic (6.07e-2)" "unprognostic (2.41e-1)" "unprognostic (2.34e-1)" "unprognostic (7.86e-2)" "unprognostic (8.14e-3)" "unprognostic (1.08e-1)" "unprognostic (2.47e-2)" "unprognostic (1.22e-2)" "unprognostic (1.71e-2)" "unprognostic (2.92e-1)" "unprognostic (9.10e-3)" "unprognostic (4.16e-1)" "unprognostic (1.66e-1)" "unprognostic (1.03e-1)" "unprognostic (1.62e-1)" "unprognostic (2.04e-1)" "unprognostic (8.48e-2)" ZFP91 "PZF, ZNF757" ENSG00000186660 "ZFP91 zinc finger protein, atypical E3 ubiquitin ligase" Q96JP5 11 58579063-58621550 "Enzymes, Predicted intracellular proteins, Transcription factors" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Early spermatids: 6.6;Endometrial secretory cells: 5.2;Late primary spermatocytes: 7.6;Late spermatids: 12.5;Parietal cells: 5.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024037, CAB025417, HPA065325, HPA074591" Enhanced Enhanced Nucleoplasm,Nucleoli NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 19 "Nucleoplasm, Nucleoli" "CAB025417: , HPA024037: , HPA065325: , HPA074591: " "unprognostic (6.77e-3)" "unprognostic (9.91e-2)" "unprognostic (3.05e-1)" "unprognostic (8.77e-3)" "unprognostic (1.37e-1)" "unprognostic (2.02e-1)" "unprognostic (6.39e-2)" "unprognostic (5.15e-2)" "unprognostic (1.27e-1)" "potential prognostic unfavorable (4.13e-5)" "potential prognostic favorable (1.52e-6)" "unprognostic (5.32e-3)" "unprognostic (2.85e-1)" "unprognostic (2.01e-2)" "unprognostic (6.13e-2)" "unprognostic (2.22e-2)" "unprognostic (2.14e-2)" "unprognostic (3.22e-2)" "unprognostic (3.27e-1)" "unprognostic (2.63e-2)" "unprognostic (3.68e-3)" "potential prognostic unfavorable (2.10e-5)" "unprognostic (7.74e-2)" "unprognostic (6.68e-2)" "unprognostic (2.22e-2)" "unprognostic (1.48e-1)" "unprognostic (6.72e-2)" "unprognostic (2.44e-1)" "unprognostic (3.81e-2)" "unprognostic (1.25e-1)" "unprognostic (1.41e-1)" ZFP92 ZNF897 ENSG00000189420 "ZFP92 zinc finger protein" A6NM28 X 153411472-153426481 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 7.5;Endometrial luminal cells: 8.2;Endometrial stromal cells: 4.7;Epididymal efferent duct ciliated cells: 5.9;Gonadotrophs: 12.1;Innate lymphoid cells: 5.0;Megakaryocytes: 6.2;Neutrophil progenitors: 8.0;Pericytes: 7.9;Peritubular myoid cells: 5.6;Pituitary stem cells: 5.9" "Cell type enhanced" "Detected in many" "midbrain-derived inhibitory: 9.7;pericyte: 9.1" "Cancer enhanced" "Detected in some" "Ovary Serous Cystadenocarcinoma (TCGA): 4.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Kidney - Fibroblasts" "Region enhanced" "Detected in many" "hypothalamus: 8.8" "Low region specificity" "Detected in all" HPA003030 Uncertain NA NA "Cluster 65: Brain - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 110: Mural cells - ECM organization" "HPA003030: " "unprognostic (3.28e-1)" "unprognostic (6.94e-2)" "unprognostic (2.22e-2)" "unprognostic (7.58e-2)" "unprognostic (5.73e-2)" "unprognostic (2.11e-2)" "unprognostic (1.75e-1)" "unprognostic (2.61e-2)" "unprognostic (7.73e-2)" "unprognostic (1.77e-1)" ZFPL1 "D11S750, MCG4" ENSG00000162300 "Zinc finger protein like 1" O95159 11 65084210-65088398 "Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 102.4;Late spermatids: 81.3;Syncytiotrophoblasts: 82.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014909, HPA017347" Enhanced Enhanced "Golgi apparatus" NA NA "Cluster 32: Basophils - Transcription" "Cluster 24: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 82 "Golgi apparatus" "HPA014909: , HPA017347: " "unprognostic (4.43e-2)" "unprognostic (1.36e-1)" "unprognostic (8.88e-2)" "unprognostic (8.52e-2)" "unprognostic (6.49e-2)" "unprognostic (4.20e-2)" "unprognostic (2.04e-2)" "unprognostic (2.80e-1)" "unprognostic (1.98e-2)" "unprognostic (4.59e-2)" "unprognostic (1.40e-1)" "unprognostic (4.06e-2)" "unprognostic (4.13e-3)" "potential prognostic unfavorable (4.73e-5)" "unprognostic (5.95e-2)" "unprognostic (2.47e-2)" "potential prognostic unfavorable (7.27e-6)" "unprognostic (8.24e-2)" "unprognostic (2.57e-1)" "unprognostic (1.17e-1)" "unprognostic (1.28e-1)" "unprognostic (1.69e-1)" "unprognostic (8.51e-3)" "unprognostic (3.54e-1)" "unprognostic (2.40e-1)" "unprognostic (6.62e-2)" "unprognostic (1.35e-1)" "unprognostic (3.42e-2)" "unprognostic (1.69e-1)" "unprognostic (2.61e-2)" "unprognostic (2.64e-2)" ZFPM1 "FOG, FOG1, ZC2HC11A, ZNF89A" ENSG00000179588 "Zinc finger protein, FOG family member 1" Q8IX07 16 88453280-88537031 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 176.6;Megakaryocyte progenitors: 191.2;Megakaryocyte-Erythroid progenitors: 140.8;Megakaryocytes: 111.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Stomach Adenocarcinoma (TCGA): 23.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Pituitary gland - Corticotropes, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030495, HPA046603" Enhanced Approved Nucleoplasm NA NA "Cluster 70: Non-specific - Protein processing" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 7 Nucleoplasm "HPA030495: , HPA046603: " "unprognostic (1.08e-1)" "unprognostic (2.70e-1)" "unprognostic (3.88e-1)" "unprognostic (1.03e-1)" "unprognostic (4.77e-1)" "unprognostic (3.56e-2)" "unprognostic (2.01e-1)" "unprognostic (5.18e-2)" "unprognostic (2.16e-1)" "unprognostic (5.81e-3)" "unprognostic (9.65e-2)" "potential prognostic favorable (2.71e-5)" "unprognostic (9.91e-3)" "unprognostic (5.74e-2)" "unprognostic (2.54e-1)" "unprognostic (6.44e-2)" "unprognostic (1.90e-1)" "unprognostic (7.19e-2)" "unprognostic (1.61e-1)" "unprognostic (4.89e-2)" "unprognostic (5.44e-3)" "unprognostic (1.72e-1)" "unprognostic (1.19e-1)" "unprognostic (1.17e-1)" "unprognostic (1.92e-1)" "unprognostic (5.88e-2)" "unprognostic (2.16e-1)" "unprognostic (2.92e-1)" ZFPM2 "FOG2, hFOG-2, ZC2HC11B, ZNF89B" ENSG00000169946 "Zinc finger protein, FOG family member 2" Q8WW38 8 104590733-105804539 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Gonadal differentiation, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.5;ovary: 32.4" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 1088.8;Brain inhibitory neurons: 651.6;Cardiomyocytes: 842.6;Fibro-adipogenic progenitors: 1464.6;Leydig cells: 918.2;Lymphatic endothelial cells: 877.0;Mesothelial cells: 2530.1;Myonuclei: 1276.6;Oligodendrocyte progenitor cells: 909.5;Thymic myoid cells: 1366.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "cerebellum: 141.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 4.3" "Adipose visceral - Mesothelial cells, Adrenal gland - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 53.1" HPA004094 Approved Supported Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 35: Non-specific - DNA binding" "Cluster 1: Neuronal - Visual perception" "Cluster 35: Neurons - Synaptic function & neurogenesis" 12 Nucleoplasm "HPA004094: " "unprognostic (2.43e-1)" "unprognostic (1.63e-1)" "unprognostic (8.48e-2)" "unprognostic (3.35e-2)" "unprognostic (3.82e-1)" "unprognostic (3.18e-1)" "unprognostic (2.13e-1)" "potential prognostic favorable (3.45e-4)" "unprognostic (1.17e-1)" "unprognostic (4.72e-2)" "unprognostic (1.93e-2)" "unprognostic (3.92e-2)" "unprognostic (4.23e-2)" "unprognostic (1.90e-1)" "unprognostic (1.20e-1)" "unprognostic (1.07e-1)" "potential prognostic unfavorable (6.22e-4)" "unprognostic (2.29e-2)" "potential prognostic unfavorable (3.85e-4)" ZFR "SPG71, ZFR1" ENSG00000056097 "Zinc finger RNA binding protein" Q96KR1 5 32354350-32444740 "Predicted intracellular proteins" "Developmental protein, DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016666 Supported Approved Nucleoplasm NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 29: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 78 Nucleoplasm "HPA016666: " "unprognostic (6.81e-2)" "unprognostic (2.50e-2)" "unprognostic (4.72e-3)" "unprognostic (2.26e-2)" "unprognostic (1.80e-1)" "unprognostic (5.61e-2)" "unprognostic (9.65e-2)" "unprognostic (4.20e-2)" "unprognostic (4.71e-2)" "potential prognostic unfavorable (3.66e-4)" "potential prognostic favorable (4.64e-8)" "unprognostic (3.45e-3)" "unprognostic (6.05e-2)" "unprognostic (6.30e-3)" "unprognostic (4.47e-2)" "unprognostic (8.08e-2)" "potential prognostic unfavorable (2.41e-4)" "unprognostic (9.01e-2)" "unprognostic (1.36e-1)" "unprognostic (2.27e-1)" "unprognostic (7.59e-2)" "unprognostic (6.48e-2)" "unprognostic (2.64e-3)" "unprognostic (4.83e-2)" "unprognostic (2.71e-2)" "unprognostic (2.34e-1)" "unprognostic (1.22e-1)" "unprognostic (2.21e-2)" "unprognostic (2.98e-1)" "unprognostic (2.22e-2)" "unprognostic (1.86e-1)" ZFR2 KIAA1086 ENSG00000105278 "Zinc finger RNA binding protein 2" Q9UPR6 19 3804024-3869038 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 15.0;pituitary gland: 27.4;retina: 10.1;testis: 14.0" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 85.1;Brain excitatory neurons: 56.4;Brain inhibitory neurons: 73.8;Cone photoreceptor cells: 84.9;Corticotrophs: 86.4;Early primary spermatocytes: 63.9;Lactotrophs: 130.1;Late primary spermatocytes: 53.6;Other brain neurons: 74.1;Retinal amacrine cells: 148.9;Retinal bipolar cells: 104.8;Retinal ganglion cells: 69.5;Retinal horizontal cells: 108.2;Rod photoreceptor cells: 91.7;Somatotrophs: 91.2;Thyrotrophs: 138.8" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 16.0;Testicular Germ Cell Tumor (TCGA): 7.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "cervical cancer: 4.5" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Prostate - Prostate glandular cells, Stomach - Gastric enteroendocrine cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043275, HPA055678" Uncertain Approved Nucleoplasm NA NA "Cluster 1: T-cells - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" Nucleoplasm "HPA043275: , HPA055678: " "unprognostic (8.04e-3)" "unprognostic (3.00e-3)" "unprognostic (2.35e-2)" "potential prognostic favorable (1.80e-4)" "unprognostic (4.34e-2)" "unprognostic (1.64e-1)" "unprognostic (2.32e-2)" "unprognostic (1.54e-2)" "unprognostic (1.58e-1)" "unprognostic (7.96e-2)" "unprognostic (8.70e-2)" "unprognostic (6.02e-2)" ZFTA "C11orf95, MGC3032" ENSG00000188070 "Zinc finger translocation associated" C9JLR9 11 63759892-63768775 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 19.4;Leydig cells: 19.4;Tuft cells: 23.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Pituitary gland - Undifferentiated cells (Pituitary gland), Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045002 Approved "Intermediate filaments" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 29: Forebrain - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 110: Mural cells - ECM organization" "Intermediate filaments" "HPA045002: " "unprognostic (9.36e-2)" "unprognostic (3.51e-3)" "unprognostic (1.65e-2)" "unprognostic (4.22e-3)" "unprognostic (1.34e-1)" "unprognostic (1.37e-1)" "unprognostic (6.37e-2)" "unprognostic (1.04e-3)" "unprognostic (3.85e-1)" "unprognostic (2.23e-2)" "unprognostic (1.40e-3)" "potential prognostic favorable (1.69e-5)" "unprognostic (1.48e-1)" "unprognostic (4.05e-1)" "unprognostic (2.33e-2)" "unprognostic (1.92e-1)" "unprognostic (3.10e-3)" "unprognostic (4.97e-2)" "unprognostic (9.62e-3)" "unprognostic (4.97e-2)" "unprognostic (5.95e-2)" "unprognostic (7.82e-3)" "unprognostic (4.44e-2)" "unprognostic (2.64e-1)" "unprognostic (4.34e-2)" "unprognostic (3.15e-1)" "unprognostic (6.60e-2)" "unprognostic (9.83e-2)" "unprognostic (2.89e-2)" "unprognostic (3.64e-2)" "unprognostic (1.05e-2)" ZFTRAF1 "CHRP, CYHR1, KIAA0496, MGC13010" ENSG00000187954 "Zinc finger TRAF-type containing 1" 8 144449582-144462871 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skeletal muscle: 9.2;testis: 9.1" "Cell type enhanced" "Detected in some" "Astrocytes: 59.9;Bergmann glia: 59.9;Brain excitatory neurons: 65.8;Brain inhibitory neurons: 59.2;Choroid plexus epithelial cells: 39.9;Distal convoluted tubule cells: 34.2;Ependymal cells: 51.1;Loop of henle epithelial cells: 23.8;Microglia: 40.2;Oligodendrocyte progenitor cells: 35.4;Oligodendrocytes: 47.4;Other brain neurons: 62.5;Papillary tip epithelial cells: 26.1;Podocytes: 25.6;Proximal tubule cells: 31.2;Renal collecting duct intercalated cells: 23.4;Renal collecting duct principal cells: 25.8;Renal connecting tubule cells: 26.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053653, HPA059543" Approved Approved Nucleoplasm NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" 1 Nucleoplasm "HPA053653: , HPA059543: " "unprognostic (1.65e-2)" "unprognostic (8.29e-2)" "unprognostic (3.48e-1)" "unprognostic (1.83e-1)" "unprognostic (5.25e-3)" "unprognostic (6.12e-2)" "unprognostic (2.23e-2)" "potential prognostic favorable (2.48e-4)" "unprognostic (4.92e-2)" "unprognostic (2.93e-1)" "unprognostic (1.16e-1)" "unprognostic (5.21e-2)" "unprognostic (2.30e-1)" "potential prognostic unfavorable (7.44e-4)" "unprognostic (8.59e-2)" "unprognostic (8.41e-2)" "unprognostic (4.64e-2)" "unprognostic (1.02e-1)" "unprognostic (1.37e-1)" "unprognostic (9.61e-2)" "unprognostic (8.52e-2)" "unprognostic (2.90e-2)" "unprognostic (3.34e-3)" "unprognostic (2.47e-2)" "unprognostic (2.71e-1)" "unprognostic (2.03e-1)" "unprognostic (2.10e-2)" "unprognostic (7.10e-2)" "unprognostic (1.27e-1)" "unprognostic (8.90e-2)" "unprognostic (1.78e-1)" ZFX ZNF926 ENSG00000005889 "Zinc finger protein X-linked" P17010 X 24149173-24216255 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gonadotrophs: 283.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA001748, HPA003877, HPA071863" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 36: Non-specific - mRNA processing" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" Nucleoplasm Nucleoli "HPA001748: , HPA003877: , HPA071863: " "unprognostic (4.78e-2)" "unprognostic (8.75e-2)" "unprognostic (2.21e-1)" "unprognostic (7.47e-2)" "unprognostic (2.10e-2)" "unprognostic (4.74e-2)" "unprognostic (2.98e-1)" "unprognostic (1.38e-1)" "unprognostic (2.82e-1)" "unprognostic (9.23e-3)" "potential prognostic favorable (4.90e-4)" "unprognostic (7.87e-3)" "unprognostic (1.18e-1)" "unprognostic (1.95e-2)" "unprognostic (9.59e-2)" "unprognostic (3.83e-1)" "unprognostic (2.01e-3)" "unprognostic (1.35e-1)" "unprognostic (2.20e-2)" "unprognostic (2.09e-1)" "unprognostic (6.11e-2)" "unprognostic (1.01e-1)" "unprognostic (9.72e-2)" "unprognostic (1.37e-1)" "unprognostic (3.22e-1)" "unprognostic (7.85e-2)" "unprognostic (3.41e-2)" "unprognostic (1.48e-1)" "unprognostic (2.58e-1)" "unprognostic (1.10e-1)" "unprognostic (2.16e-1)" ZFY ZNF911 ENSG00000067646 "Zinc finger protein Y-linked" P08048 Y 2935281-2982506 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 80.7;Late spermatids: 162.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 12.3" "Low region specificity" "Detected in all" "HPA001748, HPA071863" Uncertain Approved Nucleoplasm,Nucleoli NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 16: Non-specific - Transcription" "Cluster 47: Leukemia - Hemostasis" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 5 Nucleoplasm Nucleoli "HPA001748: , HPA071863: " "unprognostic (4.76e-1)" "unprognostic (5.79e-2)" "unprognostic (1.04e-1)" "unprognostic (1.45e-1)" "unprognostic (5.31e-2)" "potential prognostic favorable (8.16e-5)" "unprognostic (2.87e-1)" "unprognostic (1.31e-3)" "unprognostic (8.67e-2)" "unprognostic (1.41e-2)" "unprognostic (2.40e-1)" "unprognostic (1.25e-1)" "unprognostic (7.34e-2)" "unprognostic (1.78e-1)" "unprognostic (2.63e-2)" "unprognostic (9.95e-2)" "unprognostic (3.72e-1)" "unprognostic (4.25e-2)" "unprognostic (1.99e-3)" "unprognostic (4.52e-2)" "unprognostic (3.16e-2)" "unprognostic (3.05e-1)" "unprognostic (5.83e-2)" ZFYVE1 "DFCP1, KIAA1589, PPP1R172, TAFF1, ZNFN2A1" ENSG00000165861 "Zinc finger FYVE-type containing 1" Q9HBF4 14 72969451-73027131 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 181.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002898 Approved Supported "Endoplasmic reticulum" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 19: Astrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 7: Non-specific - Transcription" 2 "Endoplasmic reticulum" "HPA002898: " "unprognostic (1.57e-1)" "unprognostic (2.55e-1)" "unprognostic (3.88e-2)" "unprognostic (8.07e-3)" "unprognostic (8.41e-2)" "unprognostic (3.45e-2)" "unprognostic (2.91e-1)" "unprognostic (2.71e-1)" "unprognostic (3.44e-1)" "unprognostic (1.65e-1)" "validated prognostic favorable (2.62e-8)" "validated prognostic favorable (2.80e-4)" "unprognostic (5.56e-2)" "unprognostic (1.93e-2)" "unprognostic (1.63e-1)" "unprognostic (7.01e-2)" "unprognostic (3.30e-1)" "unprognostic (1.04e-1)" "unprognostic (4.45e-2)" "unprognostic (1.28e-2)" "potential prognostic unfavorable (7.31e-6)" "unprognostic (8.62e-2)" "unprognostic (2.60e-2)" "unprognostic (5.55e-2)" "unprognostic (7.06e-2)" "unprognostic (2.00e-1)" "unprognostic (1.40e-3)" "unprognostic (7.70e-2)" "unprognostic (2.15e-1)" "unprognostic (1.18e-1)" "unprognostic (2.61e-1)" ZFYVE16 "KIAA0305, PPP1R69" ENSG00000039319 "Zinc finger FYVE-type containing 16" Q7Z3T8 5 80408013-80483379 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 483.1;Oligodendrocytes: 871.5" "Cell type enhanced" "Detected in all" "oligodendrocyte: 1128.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 21.3;neutrophil: 21.4" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035935, HPA035936" Supported Enhanced Vesicles,Cytosol No No "Cluster 35: Neutrophils - Protein binding" "Cluster 61: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 17 "Vesicles, Cytosol" "HPA035935: , HPA035936: " "unprognostic (7.71e-3)" "unprognostic (6.13e-2)" "unprognostic (1.66e-1)" "unprognostic (3.70e-1)" "unprognostic (6.57e-2)" "unprognostic (3.01e-1)" "unprognostic (8.23e-2)" "unprognostic (8.17e-2)" "unprognostic (2.44e-2)" "unprognostic (2.77e-3)" "potential prognostic favorable (1.62e-7)" "unprognostic (3.16e-3)" "unprognostic (2.37e-1)" "unprognostic (1.81e-1)" "unprognostic (8.31e-2)" "unprognostic (2.72e-1)" "unprognostic (1.31e-1)" "unprognostic (1.04e-2)" "unprognostic (4.59e-2)" "unprognostic (2.71e-1)" "potential prognostic unfavorable (2.78e-4)" "unprognostic (1.42e-2)" "unprognostic (5.51e-3)" "unprognostic (1.99e-1)" "unprognostic (3.62e-2)" "unprognostic (6.06e-2)" "unprognostic (2.48e-1)" "unprognostic (6.55e-2)" "unprognostic (2.00e-1)" "unprognostic (4.90e-3)" "unprognostic (6.48e-2)" ZFYVE19 "ANCHR, FLJ14840, MPFYVE" ENSG00000166140 "Zinc finger FYVE-type containing 19" Q96K21 15 40807086-40815084 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" "Ciliopathy, Disease variant, Intrahepatic cholestasis, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 66.5;Cytotrophoblasts: 95.0;Esophageal apical cells: 127.7;Migrating cytotrophoblasts: 76.4;Syncytiotrophoblasts: 67.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040283, HPA041946" Uncertain NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 10 "HPA040283: , HPA041946: " "unprognostic (7.40e-2)" "unprognostic (4.00e-3)" "unprognostic (1.60e-1)" "unprognostic (9.44e-2)" "unprognostic (3.45e-2)" "potential prognostic unfavorable (4.12e-4)" "unprognostic (2.12e-1)" "unprognostic (2.83e-2)" "unprognostic (1.75e-1)" "unprognostic (4.43e-3)" "validated prognostic favorable (1.03e-6)" "validated prognostic favorable (8.51e-4)" "unprognostic (2.62e-3)" "unprognostic (2.92e-2)" "unprognostic (7.86e-3)" "unprognostic (2.37e-2)" "unprognostic (4.16e-2)" "unprognostic (1.49e-1)" "unprognostic (5.32e-2)" "unprognostic (5.63e-2)" "unprognostic (1.59e-1)" "unprognostic (8.96e-3)" "unprognostic (1.92e-3)" "unprognostic (1.67e-1)" "unprognostic (2.44e-1)" "unprognostic (6.38e-2)" "unprognostic (2.77e-1)" "unprognostic (7.56e-2)" "unprognostic (3.71e-2)" "unprognostic (2.61e-2)" "unprognostic (6.41e-3)" ZFYVE21 "MGC2550, ZF21" ENSG00000100711 "Zinc finger FYVE-type containing 21" Q9BQ24 14 103715730-103733668 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 320.5" "Cell type enhanced" "Detected in all" "Bergmann glia: 180.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055721 Uncertain NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 27: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 62: Smooth muscle cells - Muscle contraction" 26 "HPA055721: " "unprognostic (1.68e-1)" "unprognostic (7.63e-2)" "unprognostic (1.62e-1)" "unprognostic (3.45e-2)" "unprognostic (2.57e-1)" "unprognostic (2.36e-2)" "unprognostic (2.46e-1)" "unprognostic (1.64e-1)" "unprognostic (5.30e-3)" "unprognostic (1.87e-1)" "potential prognostic favorable (3.56e-5)" "unprognostic (4.52e-2)" "unprognostic (1.90e-2)" "unprognostic (5.71e-3)" "unprognostic (7.92e-2)" "unprognostic (2.84e-1)" "unprognostic (2.32e-1)" "unprognostic (2.08e-1)" "unprognostic (1.41e-1)" "unprognostic (4.76e-1)" "unprognostic (2.49e-2)" "unprognostic (5.39e-3)" "unprognostic (6.74e-2)" "unprognostic (1.17e-1)" "unprognostic (1.39e-1)" "unprognostic (2.19e-2)" "potential prognostic unfavorable (6.91e-4)" "unprognostic (9.36e-3)" "unprognostic (3.46e-1)" "unprognostic (2.18e-1)" "unprognostic (3.37e-1)" ZFYVE26 "KIAA0321, SPG15" ENSG00000072121 "Zinc finger FYVE-type containing 26" Q68DK2 14 67727374-67816590 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair" "Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 115.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 11 "plasmacytoid DC: 4.9" "Lineage enriched" "Detected in single" 11 "dendritic cells: 4.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055500 Approved NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 79: Photoreceptor cells - Phototransduction" "HPA055500: " "unprognostic (1.25e-1)" "unprognostic (1.24e-1)" "unprognostic (1.68e-1)" "unprognostic (2.11e-2)" "unprognostic (1.98e-2)" "unprognostic (2.26e-2)" "unprognostic (2.22e-1)" "unprognostic (1.82e-2)" "unprognostic (4.41e-2)" "unprognostic (6.78e-2)" "potential prognostic favorable (1.93e-6)" "unprognostic (2.56e-3)" "unprognostic (1.26e-2)" "potential prognostic unfavorable (8.40e-6)" "unprognostic (3.25e-1)" "unprognostic (9.82e-2)" "unprognostic (1.49e-1)" "unprognostic (1.33e-1)" "unprognostic (2.02e-1)" "unprognostic (1.62e-2)" "unprognostic (2.06e-1)" "unprognostic (1.18e-2)" "unprognostic (5.86e-3)" "unprognostic (1.92e-2)" "unprognostic (3.42e-1)" "unprognostic (2.83e-1)" "unprognostic (1.29e-1)" "unprognostic (1.10e-1)" "unprognostic (6.69e-2)" "unprognostic (1.94e-2)" "unprognostic (7.87e-2)" ZFYVE27 "FLJ32919, SPG33" ENSG00000155256 "Zinc finger FYVE-type containing 27" Q5T4F4 10 97737121-97760907 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037523, HPA069876" Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 20: Pituitary gland - Hormone signaling" "Cluster 1: Neurons - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 7: Non-specific - Transcription" 27 "Nucleoplasm, Vesicles" Cytosol "HPA037523: , HPA069876: " "unprognostic (6.23e-2)" "unprognostic (9.92e-2)" "unprognostic (1.70e-2)" "unprognostic (8.44e-2)" "unprognostic (1.59e-3)" "unprognostic (1.56e-1)" "unprognostic (8.60e-2)" "potential prognostic favorable (1.04e-4)" "unprognostic (1.31e-1)" "unprognostic (3.10e-1)" "unprognostic (9.61e-2)" "unprognostic (2.05e-2)" "unprognostic (9.01e-3)" "unprognostic (5.73e-2)" "unprognostic (1.69e-1)" "unprognostic (4.92e-2)" "unprognostic (3.07e-1)" "unprognostic (6.50e-2)" "unprognostic (1.87e-1)" "unprognostic (3.59e-2)" "unprognostic (1.74e-1)" "unprognostic (3.38e-3)" "unprognostic (6.63e-2)" "unprognostic (4.12e-2)" "unprognostic (7.95e-2)" "unprognostic (2.59e-1)" "unprognostic (9.47e-3)" "unprognostic (7.33e-3)" "unprognostic (3.24e-1)" "unprognostic (4.78e-2)" "unprognostic (3.37e-3)" ZFYVE28 "KIAA1643, lst-2" ENSG00000159733 "Zinc finger FYVE-type containing 28" Q9HCC9 4 2269582-2418651 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "brain: 60.2" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 210.3;Brain inhibitory neurons: 156.4;Choroid plexus epithelial cells: 196.9;Cone photoreceptor cells: 182.2;Retinal ganglion cells: 224.0;Rod photoreceptor cells: 165.8;Sertoli cells: 211.0;T-cells: 141.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 1.8;T-cells: 1.9" "Low cancer specificity" "Detected in many" "Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038175, HPA057587" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 71: Cerebellum - Nervous system development" "Cluster 15: Non-specific - Transcription" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" "Plasma membrane, Cytosol" Nucleoplasm "HPA038175: , HPA057587: " "unprognostic (3.12e-3)" "unprognostic (1.13e-1)" "unprognostic (8.83e-2)" "unprognostic (6.67e-3)" "unprognostic (1.67e-1)" "unprognostic (2.51e-1)" "unprognostic (7.01e-3)" "unprognostic (4.08e-2)" "unprognostic (1.04e-1)" "unprognostic (8.79e-2)" "potential prognostic favorable (2.35e-4)" "unprognostic (2.38e-2)" "unprognostic (1.36e-3)" "unprognostic (2.16e-1)" "potential prognostic favorable (3.39e-5)" "unprognostic (1.05e-1)" "unprognostic (5.00e-2)" "unprognostic (4.64e-3)" "unprognostic (7.72e-2)" "unprognostic (6.27e-3)" "unprognostic (1.86e-1)" "unprognostic (6.88e-3)" "unprognostic (2.73e-3)" "unprognostic (1.34e-1)" "unprognostic (2.25e-1)" "unprognostic (8.96e-2)" "unprognostic (5.79e-2)" "unprognostic (7.62e-2)" "unprognostic (1.70e-1)" "unprognostic (1.47e-1)" "unprognostic (1.15e-1)" ZFYVE9 "MADHIP, PPP1R173, SARA, SMADIP" ENSG00000157077 "Zinc finger FYVE-type containing 9" O95405 1 52142089-52348671 "Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 359.3;Podocytes: 343.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Lung - Alveolar cells type 1, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017702, HPA065852, HPA065862" Approved Enhanced Vesicles,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 23 "Vesicles, Cytosol" "CAB017702: , HPA065852: , HPA065862: " "unprognostic (3.49e-1)" "unprognostic (1.47e-1)" "unprognostic (9.73e-2)" "unprognostic (6.82e-2)" "unprognostic (1.86e-3)" "unprognostic (2.05e-1)" "unprognostic (2.31e-2)" "unprognostic (3.10e-1)" "unprognostic (2.68e-1)" "unprognostic (2.89e-2)" "validated prognostic favorable (2.62e-7)" "validated prognostic favorable (1.94e-4)" "unprognostic (1.46e-1)" "unprognostic (2.95e-3)" "unprognostic (2.45e-1)" "unprognostic (6.25e-2)" "unprognostic (1.71e-1)" "unprognostic (1.03e-1)" "unprognostic (1.01e-2)" "unprognostic (1.12e-1)" "unprognostic (1.98e-1)" "unprognostic (1.05e-1)" "unprognostic (8.03e-2)" "unprognostic (1.33e-1)" "unprognostic (2.55e-2)" "unprognostic (4.73e-2)" "unprognostic (1.04e-1)" "unprognostic (4.02e-1)" "unprognostic (1.37e-1)" "unprognostic (7.39e-3)" "unprognostic (1.40e-1)" ZG16 "hZG16, JCLN, JCLN1, ZG16A" ENSG00000174992 "Zymogen granule protein 16" O60844 16 29778256-29782973 "Predicted secreted proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 22 "intestine: 449.0" "Cell type enriched" "Detected in some" 52 "Goblet cells: 48497.2" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Colon Adenocarcinoma (TCGA): 17.4;Rectum Adenocarcinoma (TCGA): 34.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enterocytes, Liver - Hepatocytes, Testis - Early spermatids" "Not detected" "Not detected" "HPA052066, HPA052512" Enhanced Approved "Mid piece,Principal piece,Annulus" "Secreted to digestive system" Transport NA NA 1200000 "Cluster 77: Intestine - Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 70: Intestinal goblet cells - Mucin production" 9 Annulus "Mid piece, Principal piece" "HPA052066: , HPA052512: " "unprognostic (2.04e-1)" "unprognostic (1.81e-2)" "unprognostic (6.64e-3)" "unprognostic (3.22e-2)" "unprognostic (3.65e-3)" "unprognostic (4.29e-2)" "unprognostic (5.33e-2)" ZG16B "HRPE773, JCLN2, PRO1567" ENSG00000162078 "Zymogen granule protein 16B" Q96DA0 16 2830253-2839585 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 826 "salivary gland: 80766.9" "Cell type enriched" "Detected in some" 4 "Salivary acinar cells: 453.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 96.8;Prostate Adenocarcinoma (TCGA): 120.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "intermediate monocyte: 8.1;non-classical monocyte: 9.3" "Lineage enriched" "Detected in single" 15 "monocytes: 9.3" "Cancer enhanced" "Detected in many" "breast cancer: 12.8" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "HPA041125, HPA053549" Enhanced Approved Nucleoplasm,Vesicles "Secreted to digestive system" "No annotated function" NA NA 2000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 82: Salivary gland - Secretion" "Cluster 27: Breast cancer - Unknown function" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 37 Vesicles Nucleoplasm "HPA041125: , HPA053549: " "unprognostic (1.13e-1)" "unprognostic (5.45e-2)" "unprognostic (2.09e-1)" "unprognostic (3.01e-1)" "unprognostic (5.02e-2)" "unprognostic (1.04e-1)" "unprognostic (3.17e-2)" "unprognostic (2.32e-2)" "potential prognostic unfavorable (8.29e-4)" "unprognostic (9.67e-2)" "unprognostic (5.96e-2)" "unprognostic (8.17e-2)" "unprognostic (1.69e-1)" "unprognostic (7.60e-2)" "unprognostic (5.41e-1)" "unprognostic (9.21e-2)" "unprognostic (2.70e-3)" "unprognostic (1.34e-2)" "unprognostic (6.27e-2)" "unprognostic (1.02e-1)" "unprognostic (1.16e-1)" "unprognostic (6.48e-2)" "unprognostic (3.55e-1)" "unprognostic (8.32e-2)" ZGLP1 "GATAD3, GLP-1, GLP1" ENSG00000220201 "Zinc finger GATA like protein 1" P0C6A0 19 10304803-10309880 "Predicted intracellular proteins, Transcription factors" "Differentiation, Oogenesis, Spermatogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.7" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 19.0;Kupffer cells: 18.4;Megakaryocytes: 49.5;Platelets: 26.8;Undifferentiated spermatogonia: 15.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Minor salivary glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA049855 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 64: Non-specific - Transcription" "Cluster 53: Neurons - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 47: Platelets - Hemostasis" "Nucleoplasm, Vesicles" "HPA049855: " "unprognostic (2.36e-2)" "unprognostic (9.30e-2)" "unprognostic (1.13e-1)" "unprognostic (7.40e-2)" "unprognostic (1.46e-1)" "unprognostic (3.03e-1)" "unprognostic (6.03e-3)" "unprognostic (1.05e-1)" "unprognostic (1.14e-1)" "unprognostic (1.54e-1)" "unprognostic (1.31e-1)" "unprognostic (3.52e-2)" "unprognostic (8.72e-3)" "potential prognostic favorable (6.16e-5)" "unprognostic (1.94e-2)" "unprognostic (6.36e-2)" "unprognostic (2.41e-1)" "unprognostic (5.32e-2)" "unprognostic (2.29e-1)" "unprognostic (1.16e-1)" ZGPAT "dJ583P15.3, FLJ14972, GPATC6, GPATCH6, KIAA1847, MGC44880, ZC3H9, ZC3HDC9, ZIP" ENSG00000197114 "Zinc finger CCCH-type and G-patch domain containing" Q8N5A5 20 63707465-63736142 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "liver: 123.4" "Cell type enhanced" "Detected in some" "Astrocytes: 7.5;Bergmann glia: 7.3;Brain excitatory neurons: 9.1;Brain inhibitory neurons: 8.9;Cardiomyocytes: 30.8;Choroid plexus epithelial cells: 25.8;Ependymal cells: 6.4;Epicardial cells: 11.4;Microglia: 8.2;Oligodendrocyte progenitor cells: 5.7;Oligodendrocytes: 7.5;Other brain neurons: 8.1;Tuft cells: 11.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056705 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 6: Non-specific - Immune response" "Cluster 62: Non-specific - Plasma proteins" "Cluster 22: Non-specific - Basic cellular functions" 39 "Nucleoplasm, Plasma membrane" "HPA056705: " "unprognostic (5.26e-2)" "unprognostic (1.27e-1)" "unprognostic (3.59e-1)" "unprognostic (1.61e-2)" "unprognostic (3.99e-1)" "unprognostic (2.70e-3)" "unprognostic (1.50e-1)" "unprognostic (2.02e-2)" "unprognostic (1.94e-1)" "unprognostic (8.14e-2)" "unprognostic (2.68e-1)" "unprognostic (1.07e-1)" "unprognostic (1.36e-2)" "unprognostic (5.69e-2)" "unprognostic (8.64e-2)" "unprognostic (2.11e-1)" "unprognostic (2.64e-1)" "unprognostic (7.44e-2)" "unprognostic (4.80e-1)" "unprognostic (1.92e-1)" "unprognostic (7.20e-2)" "unprognostic (1.22e-2)" "unprognostic (3.13e-3)" "unprognostic (1.61e-1)" "unprognostic (2.90e-2)" "potential prognostic favorable (3.13e-4)" "unprognostic (1.16e-2)" "unprognostic (4.04e-1)" "unprognostic (2.40e-1)" "unprognostic (4.95e-2)" "unprognostic (3.07e-2)" ZGRF1 "C4orf21, FLJ11331" ENSG00000138658 "Zinc finger GRF-type containing 1" Q86YA3 4 112539333-112636995 "Predicted intracellular proteins" "DNA damage, DNA repair" "Helicase, Hydrolase, Isomerase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 7.5" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 57.1;Erythrocyte progenitors: 86.1;Monocyte progenitors: 58.3;Neutrophil progenitors: 63.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 6.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Region enriched" "Detected in single" 5 "hippocampal formation: 3.4" "HPA030704, HPA030705, HPA030706" Uncertain Approved Nucleoplasm NA Yes "Cluster 13: Non-specific - Mitochondria" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 27: Non-specific - Cell proliferation" 6 Nucleoplasm "HPA030704: , HPA030705: , HPA030706: " "unprognostic (4.05e-1)" "unprognostic (2.31e-2)" "unprognostic (3.20e-2)" "unprognostic (2.15e-1)" "unprognostic (3.87e-2)" "unprognostic (1.91e-1)" "unprognostic (2.70e-2)" "unprognostic (1.26e-1)" "potential prognostic unfavorable (2.70e-4)" "unprognostic (2.25e-1)" "unprognostic (4.42e-2)" "unprognostic (2.72e-1)" "potential prognostic unfavorable (4.67e-4)" "unprognostic (8.70e-2)" "unprognostic (4.68e-3)" "unprognostic (1.25e-2)" "unprognostic (4.47e-1)" "unprognostic (1.05e-1)" ZHX1 ENSG00000165156 "Zinc fingers and homeoboxes 1" Q9UKY1 8 123248451-123275541 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 11.3;Late spermatids: 13.8" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055357 Supported Nucleoplasm No No "Cluster 33: Non-specific - ATP binding" "Cluster 76: Non-specific - Metabolism" "Cluster 55: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 24 Nucleoplasm "HPA055357: " "unprognostic (1.12e-2)" "unprognostic (1.31e-2)" "unprognostic (1.64e-1)" "unprognostic (2.01e-2)" "unprognostic (1.27e-1)" "potential prognostic unfavorable (3.64e-4)" "unprognostic (1.39e-1)" "unprognostic (2.06e-1)" "unprognostic (5.83e-2)" "unprognostic (3.29e-3)" "potential prognostic favorable (1.22e-5)" "unprognostic (3.51e-3)" "unprognostic (2.27e-1)" "unprognostic (5.21e-2)" "unprognostic (3.48e-1)" "unprognostic (2.96e-2)" "unprognostic (2.19e-2)" "unprognostic (1.07e-1)" "unprognostic (3.09e-1)" "unprognostic (6.11e-2)" "unprognostic (2.91e-2)" "unprognostic (1.58e-1)" "unprognostic (4.40e-3)" "unprognostic (3.09e-2)" "unprognostic (2.52e-1)" "unprognostic (2.96e-2)" "unprognostic (1.20e-1)" "unprognostic (3.07e-1)" "unprognostic (1.90e-1)" "unprognostic (2.87e-2)" "unprognostic (2.58e-2)" ZHX1-C8orf76 ENSG00000259305 "ZHX1-C8orf76 readthrough" Q96EF9 8 123226189-123274284 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 13.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA023708 Uncertain Uncertain Nucleoplasm,Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 55: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 13 Nucleoplasm Cytosol "HPA023708: " "unprognostic (4.38e-2)" "unprognostic (2.24e-1)" "unprognostic (1.69e-2)" "unprognostic (8.90e-2)" "unprognostic (6.98e-2)" "unprognostic (9.31e-2)" "unprognostic (2.06e-2)" "unprognostic (6.54e-2)" "unprognostic (7.21e-3)" "validated prognostic unfavorable (2.17e-7)" "validated prognostic unfavorable (1.97e-5)" "unprognostic (1.29e-2)" "unprognostic (1.97e-3)" "potential prognostic unfavorable (6.56e-4)" "unprognostic (5.35e-2)" "unprognostic (2.99e-3)" "unprognostic (3.47e-2)" "unprognostic (5.51e-2)" "unprognostic (4.43e-1)" "unprognostic (1.57e-1)" "potential prognostic unfavorable (1.13e-6)" "unprognostic (5.98e-2)" "unprognostic (2.79e-1)" "unprognostic (1.03e-1)" "unprognostic (1.23e-2)" "unprognostic (1.36e-1)" "unprognostic (3.82e-1)" "unprognostic (2.97e-2)" "unprognostic (2.03e-2)" ZHX2 KIAA0854 ENSG00000178764 "Zinc fingers and homeoboxes 2" Q9Y6X8 8 122781655-122974510 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Somatotrophs: 847.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006769, HPA006996" Enhanced Enhanced Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 103: Non-specific - Basic cellular processes" 12 Nucleoplasm "HPA006769: , HPA006996: " "unprognostic (7.98e-3)" "unprognostic (5.08e-2)" "unprognostic (1.20e-1)" "unprognostic (3.28e-1)" "unprognostic (3.98e-1)" "unprognostic (8.09e-3)" "unprognostic (4.68e-2)" "unprognostic (3.61e-2)" "unprognostic (3.24e-2)" "unprognostic (1.64e-1)" "unprognostic (1.46e-3)" "potential prognostic favorable (2.38e-4)" "unprognostic (2.44e-1)" "unprognostic (4.22e-3)" "unprognostic (2.54e-2)" "unprognostic (3.31e-1)" "unprognostic (2.14e-1)" "unprognostic (1.01e-1)" "unprognostic (9.32e-2)" "unprognostic (1.37e-1)" "unprognostic (7.42e-2)" "unprognostic (1.36e-1)" "unprognostic (3.45e-2)" "unprognostic (3.16e-1)" "unprognostic (4.28e-2)" "unprognostic (1.51e-1)" "unprognostic (9.85e-2)" "unprognostic (4.01e-2)" "unprognostic (1.30e-1)" "unprognostic (4.42e-2)" "unprognostic (4.14e-2)" ZHX3 "KIAA0395, TIX1" ENSG00000174306 "Zinc fingers and homeoboxes 3" Q9H4I2 20 41178448-41317731 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 630.5;Bergmann glia: 769.4;Loop of henle epithelial cells: 377.5;Proximal tubule cells: 454.9" "Cell type enhanced" "Detected in all" "Bergmann glia: 785.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Smooth muscle cells, Skin - Macrophages, Spleen - Fibroblasts_2, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046498 Supported Nucleoplasm NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 72: Kidney - Transmembrane transport" "Cluster 44: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 28: Astrocytes - Homeostasis & neuron support" 9 Nucleoplasm "HPA046498: " "unprognostic (2.31e-2)" "unprognostic (3.87e-2)" "unprognostic (1.50e-2)" "unprognostic (1.35e-3)" "unprognostic (1.38e-2)" "unprognostic (1.68e-1)" "unprognostic (3.68e-2)" "unprognostic (9.34e-2)" "unprognostic (3.31e-2)" "unprognostic (9.24e-2)" "potential prognostic favorable (6.00e-4)" "unprognostic (2.60e-2)" "unprognostic (1.92e-2)" "unprognostic (4.51e-2)" "unprognostic (1.02e-2)" "unprognostic (7.97e-2)" "unprognostic (1.35e-1)" "unprognostic (4.93e-2)" "unprognostic (3.12e-1)" "unprognostic (8.19e-3)" "potential prognostic unfavorable (6.21e-5)" "unprognostic (1.69e-1)" "unprognostic (1.67e-1)" "unprognostic (5.74e-2)" "unprognostic (5.45e-2)" "unprognostic (8.47e-3)" "unprognostic (2.27e-1)" "unprognostic (5.36e-2)" "unprognostic (3.87e-1)" "unprognostic (1.51e-3)" "unprognostic (8.57e-2)" ZIC1 "ZIC, ZNF201" ENSG00000152977 "Zic family member 1" Q15915 3 147393422-147510293 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Craniosynostosis, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 27 "brain: 536.2" "Cell type enhanced" "Detected in some" "Astrocytes: 95.0;Bergmann glia: 619.8;Brain excitatory neurons: 143.8;Choroid plexus epithelial cells: 104.9;Ependymal cells: 285.8;Myonuclei: 73.4;Myosatellite cells: 80.3;Oligodendrocytes: 57.9" "Cell type enhanced" "Detected in many" "Bergmann glia: 665.5;fibroblast: 888.0;pericyte: 644.8" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 56.6" "Region enriched" "Detected in all" 5 "cerebellum: 1312.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 28.8" "Region enhanced" "Detected in all" "cerebellum: 207.5" "Region enriched" "Detected in all" 8 "cerebellum: 608.2" HPA004098 Supported Supported Nucleoplasm NA NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 5: Rhabdoid - Unknown function" "Cluster 22: Non-specific - Basic cellular functions" 59 Nucleoplasm "HPA004098: " "unprognostic (2.90e-2)" "unprognostic (3.67e-1)" "unprognostic (1.16e-1)" "unprognostic (2.12e-2)" "unprognostic (1.69e-2)" "unprognostic (3.02e-1)" "unprognostic (2.05e-1)" "unprognostic (6.22e-2)" "unprognostic (1.08e-1)" "unprognostic (1.06e-1)" "unprognostic (8.93e-2)" "unprognostic (2.80e-1)" "unprognostic (9.44e-2)" "unprognostic (1.98e-1)" "unprognostic (6.19e-2)" "unprognostic (9.92e-2)" "unprognostic (8.96e-2)" ZIC2 HPE5 ENSG00000043355 "Zic family member 2" O95409 13 99981784-99986765 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Disease variant, Holoprosencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "brain: 150.4" "Cell type enhanced" "Detected in some" "Astrocytes: 23.7;Bergmann glia: 82.8;Brain excitatory neurons: 47.8;Brain inhibitory neurons: 8.4;Choroid plexus epithelial cells: 36.7;Ependymal cells: 28.5;Müller glia: 8.7;Other brain neurons: 11.4" "Cell type enhanced" "Detected in many" "endothelial cell: 114.2;fibroblast: 151.7;upper rhombic lip: 149.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "cerebellum: 255.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 203.2" HPA055031 Supported "Nuclear bodies" NA NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 4 "Nuclear bodies" "HPA055031: " "unprognostic (3.80e-1)" "potential prognostic unfavorable (5.13e-6)" "unprognostic (2.06e-1)" "unprognostic (1.20e-3)" "unprognostic (2.83e-2)" "unprognostic (1.12e-1)" "unprognostic (1.91e-1)" "unprognostic (1.50e-2)" "unprognostic (2.19e-2)" "validated prognostic unfavorable (2.08e-4)" "validated prognostic unfavorable (1.08e-4)" "unprognostic (9.40e-3)" "unprognostic (3.71e-1)" "unprognostic (4.26e-2)" "unprognostic (2.22e-1)" "unprognostic (1.98e-2)" "unprognostic (5.94e-2)" "unprognostic (2.81e-1)" "unprognostic (5.90e-3)" "unprognostic (2.05e-1)" "unprognostic (2.24e-1)" "unprognostic (3.78e-2)" ZIC3 "HTX, HTX1, ZNF203" ENSG00000156925 "Zic family member 3" O60481 X 137566127-137577691 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant, Heterotaxy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 17.7" "Cell type enhanced" "Detected in some" "Bergmann glia: 23.8;Brain excitatory neurons: 3.4;Choroid plexus epithelial cells: 2.9;Ependymal cells: 1.8;Müller glia: 5.0;Other brain neurons: 6.6;Undifferentiated spermatogonia: 2.7" "Cell type enhanced" "Detected in some" "Bergmann glia: 33.5;endothelial cell: 28.2;fibroblast: 14.8" "Cancer enriched" "Detected in single" 11 "Testicular Germ Cell Tumor (TCGA): 8.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 9 "testis cancer: 22.8" "Pituitary gland - Fibroblasts, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052936, HPA069523" Uncertain Supported Nucleoplasm NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 15: Non-specific - Transcription" "Cluster 34: Testis cancer - Unknown function" "Cluster 104: Brain endothelial cells - Blood brain barrier" 1 Nucleoplasm "HPA052936: , HPA069523: " "unprognostic (1.16e-2)" "unprognostic (3.37e-1)" ZIC4 ENSG00000174963 "Zic family member 4" Q8N9L1 3 147386046-147406809 "Human disease related genes, Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "brain: 91.7" "Cell type enhanced" "Detected in some" "Astrocytes: 7.8;Bergmann glia: 75.3;Brain excitatory neurons: 43.8;Choroid plexus epithelial cells: 16.3;Ependymal cells: 19.8;Late spermatids: 19.2;Myonuclei: 19.0;Myosatellite cells: 8.5;Oligodendrocytes: 8.0;Other brain neurons: 13.5" "Cell type enhanced" "Detected in many" "Bergmann glia: 79.9;fibroblast: 88.2;pericyte: 77.2;upper rhombic lip: 128.2" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 2.5;Ovary Serous Cystadenocarcinoma (TCGA): 2.5" "Region enhanced" "Detected in all" "cerebellum: 153.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 8 "cerebellum: 84.6" HPA030194 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 5: Rhabdoid - Unknown function" "Cluster 2: Cerebellar granular cells - Neuronal signaling" Nucleoplasm Cytosol "HPA030194: " "unprognostic (2.89e-3)" "unprognostic (1.61e-3)" "unprognostic (2.37e-1)" "unprognostic (1.87e-1)" "unprognostic (1.63e-1)" "unprognostic (8.43e-2)" ZIC5 ENSG00000139800 "Zic family member 5" Q96T25 13 99962964-99971767 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 26.6" "Group enriched" "Detected in some" 5 "Astrocytes: 20.9;Bergmann glia: 39.7;Brain excitatory neurons: 19.0;Choroid plexus epithelial cells: 36.7;Ependymal cells: 15.2" "Cell type enhanced" "Detected in many" "Bergmann glia: 39.6;choroid plexus epithelial cell: 53.1;endothelial cell: 43.5;upper rhombic lip: 70.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Spermatocytes" "Group enriched" "Detected in all" 5 "basal ganglia: 18.9;cerebellum: 18.4;thalamus: 5.3" "Region enriched" "Detected in all" 7 "cerebellum: 51.0" HPA074045 Uncertain Nucleoplasm,Vesicles NA NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 2: Cerebellar granular cells - Neuronal signaling" "Nucleoplasm, Vesicles" "HPA074045: " "unprognostic (4.93e-3)" "unprognostic (4.47e-2)" "unprognostic (1.55e-1)" "unprognostic (1.90e-2)" "unprognostic (1.63e-1)" "unprognostic (1.35e-1)" "unprognostic (2.32e-1)" "unprognostic (2.49e-3)" "unprognostic (1.91e-1)" "unprognostic (2.24e-1)" "unprognostic (9.01e-2)" ZIK1 ZNF762 ENSG00000171649 "Zinc finger protein interacting with K protein 1" Q3SY52 19 57578456-57593890 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 20.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 17.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059975 Uncertain Approved "Intermediate filaments" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 1 "Intermediate filaments" "HPA059975: " "unprognostic (5.77e-3)" "unprognostic (1.25e-2)" "unprognostic (1.00e-1)" "unprognostic (1.28e-1)" "unprognostic (2.26e-1)" "unprognostic (3.05e-1)" "unprognostic (7.61e-2)" "validated prognostic favorable (1.15e-6)" "validated prognostic favorable (6.34e-4)" "unprognostic (1.77e-3)" "unprognostic (1.20e-2)" "unprognostic (1.06e-2)" "unprognostic (1.17e-2)" "unprognostic (1.38e-1)" "unprognostic (1.88e-1)" "unprognostic (2.60e-1)" "unprognostic (1.61e-3)" "unprognostic (5.97e-2)" "unprognostic (2.93e-1)" "unprognostic (1.56e-1)" "unprognostic (5.57e-2)" "unprognostic (1.16e-1)" "unprognostic (2.93e-1)" "unprognostic (1.22e-2)" "unprognostic (1.33e-1)" ZIM2 ZNF656 ENSG00000269699 "Zinc finger imprinted 2" Q9NZV7 19 56774547-56840731 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "ovary: 3.0;placenta: 1.9;testis: 3.0" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 29.2;Differentiating spermatogonia: 40.9;Early primary spermatocytes: 38.7;Early spermatids: 77.3;Lactotrophs: 30.8;Late spermatids: 59.1;Retinal amacrine cells: 50.7;Retinal ganglion cells: 54.1;Retinal horizontal cells: 64.1;Somatotrophs: 26.0;Thyrotrophs: 26.3;Undifferentiated spermatogonia: 36.6" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Rhabdoid: 1.3" "Testis - Early spermatids, Testis - Late spermatids" HPA071856 Approved "Nuclear speckles,Cytosol" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 109: Neurons - Neuronal signaling" 32 "Nuclear speckles" Cytosol "HPA071856: " "unprognostic (8.77e-2)" "unprognostic (3.77e-2)" "unprognostic (4.27e-1)" ZIM3 ZNF657 ENSG00000141946 "Zinc finger imprinted 3" Q96PE6 19 57134096-57145202 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 2.1;Undifferentiated spermatogonia: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" HPA034575 Uncertain NA NA "Cluster 48: Non-specific - Mixed function" "Cluster 61: BICR 18 - Protein kinases" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 1 "HPA034575: " ZKSCAN1 "KOX18, PHZ-37, ZNF139, ZNF36, ZSCAN33" ENSG00000106261 "Zinc finger with KRAB and SCAN domains 1" P17029 7 100015572-100041689 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Prostatic glandular cells: 381.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006672 Uncertain Approved "Nucleoplasm,Nuclear bodies,Mitochondria" Yes No "Cluster 30: Non-specific - DNA binding" "Cluster 70: Non-specific - Protein processing" "Cluster 6: Non-specific - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 14 "Nucleoplasm, Nuclear bodies" Mitochondria "HPA006672: " "unprognostic (1.27e-2)" "unprognostic (2.73e-2)" "unprognostic (3.15e-1)" "unprognostic (1.32e-2)" "unprognostic (2.95e-1)" "unprognostic (8.93e-3)" "unprognostic (3.75e-1)" "unprognostic (1.12e-1)" "unprognostic (2.11e-2)" "unprognostic (6.31e-3)" "potential prognostic favorable (5.79e-4)" "unprognostic (8.01e-3)" "unprognostic (4.17e-2)" "unprognostic (2.56e-2)" "unprognostic (8.18e-3)" "unprognostic (1.23e-1)" "unprognostic (2.65e-2)" "unprognostic (1.45e-2)" "unprognostic (3.29e-2)" "unprognostic (3.87e-3)" "unprognostic (2.80e-1)" "unprognostic (5.05e-2)" "unprognostic (2.96e-1)" "unprognostic (1.12e-1)" "unprognostic (9.75e-2)" "unprognostic (3.97e-1)" "unprognostic (1.60e-2)" "unprognostic (2.77e-1)" "unprognostic (4.66e-1)" "unprognostic (1.29e-1)" "unprognostic (1.09e-1)" ZKSCAN2 "FLJ23199, ZNF694, ZSCAN34" ENSG00000155592 "Zinc finger with KRAB and SCAN domains 2" Q63HK3 16 25236001-25257845 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 15.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049141 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus" NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 79: Photoreceptor cells - Phototransduction" Nucleoplasm "Nucleoli fibrillar center, Golgi apparatus" "HPA049141: " "unprognostic (1.55e-1)" "unprognostic (1.22e-1)" "unprognostic (3.73e-2)" "unprognostic (1.05e-1)" "unprognostic (3.54e-1)" "unprognostic (3.49e-2)" "unprognostic (1.84e-1)" "potential prognostic favorable (6.05e-4)" "unprognostic (2.12e-1)" "potential prognostic favorable (6.75e-5)" "unprognostic (1.93e-1)" "unprognostic (3.64e-3)" "unprognostic (6.64e-2)" "unprognostic (3.47e-1)" "unprognostic (2.13e-1)" "unprognostic (2.72e-1)" "potential prognostic favorable (6.30e-4)" "unprognostic (3.32e-2)" "unprognostic (1.12e-1)" "unprognostic (1.55e-3)" "unprognostic (4.43e-2)" "unprognostic (3.07e-1)" "unprognostic (2.06e-2)" "unprognostic (1.05e-1)" "unprognostic (3.72e-1)" "unprognostic (1.66e-1)" "unprognostic (5.30e-1)" "unprognostic (7.78e-2)" "unprognostic (1.26e-1)" ZKSCAN3 "ZF47, Zfp47, ZNF306, ZNF309, ZSCAN35" ENSG00000189298 "Zinc finger with KRAB and SCAN domains 3" Q9BRR0 6 28349947-28369172 "Predicted intracellular proteins, Transcription factors" "Autophagy, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epicardial cells: 36.4;Tuft cells: 34.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA009637, HPA060116" Approved Supported Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 61: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 47: Leukemia - Hemostasis" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 14 Nucleoplasm "HPA009637: , HPA060116: " "unprognostic (1.18e-2)" "unprognostic (6.41e-2)" "unprognostic (3.55e-1)" "unprognostic (6.85e-2)" "unprognostic (1.45e-1)" "unprognostic (3.00e-1)" "unprognostic (1.43e-2)" "unprognostic (3.40e-2)" "unprognostic (5.14e-2)" "unprognostic (7.08e-3)" "unprognostic (5.63e-3)" "unprognostic (8.50e-3)" "unprognostic (6.53e-2)" "unprognostic (1.01e-3)" "unprognostic (2.23e-1)" "unprognostic (2.88e-2)" "unprognostic (3.59e-2)" "unprognostic (2.37e-1)" "unprognostic (1.08e-1)" "unprognostic (5.96e-2)" "unprognostic (1.92e-3)" "unprognostic (3.49e-2)" "unprognostic (1.73e-1)" "unprognostic (2.16e-1)" "unprognostic (2.84e-3)" "unprognostic (2.70e-1)" "unprognostic (3.13e-2)" "unprognostic (1.96e-1)" "unprognostic (1.29e-1)" "unprognostic (2.58e-2)" "unprognostic (2.04e-1)" ZKSCAN4 "FLJ32136, P1P373C6, p373c6.1, ZNF307, ZNF427, ZSCAN36" ENSG00000187626 "Zinc finger with KRAB and SCAN domains 4" Q969J2 6 28241697-28252269 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 27.5;Kupffer cells: 33.8;Late primary spermatocytes: 61.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA009637 Approved Supported Nucleoplasm NA NA "Cluster 41: Basophils - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 2: Neurons - Nucleosome" "Cluster 28: Non-specific - Nuclear processes" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 35 Nucleoplasm "HPA009637: " "unprognostic (1.51e-1)" "unprognostic (1.64e-1)" "unprognostic (1.68e-1)" "unprognostic (3.07e-2)" "unprognostic (2.25e-1)" "unprognostic (3.86e-1)" "unprognostic (4.69e-2)" "potential prognostic favorable (9.46e-4)" "unprognostic (1.06e-2)" "potential prognostic favorable (6.35e-4)" "unprognostic (7.81e-2)" "unprognostic (1.97e-1)" "potential prognostic unfavorable (2.62e-7)" "unprognostic (1.55e-1)" "unprognostic (3.52e-2)" "unprognostic (3.09e-1)" "unprognostic (1.27e-1)" "unprognostic (2.85e-3)" "unprognostic (2.76e-2)" "unprognostic (5.07e-2)" "unprognostic (5.50e-2)" "unprognostic (1.91e-1)" "unprognostic (4.50e-2)" "unprognostic (1.07e-3)" "unprognostic (9.49e-3)" "unprognostic (2.04e-3)" "unprognostic (1.33e-1)" "unprognostic (1.74e-1)" "unprognostic (1.30e-1)" "unprognostic (7.52e-2)" ZKSCAN5 "ZFP95, ZNF914, ZSCAN37" ENSG00000196652 "Zinc finger with KRAB and SCAN domains 5" Q9Y2L8 7 99504662-99534700 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003201 Uncertain Approved "Intermediate filaments" No No "Cluster 33: Non-specific - ATP binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 16: Non-specific - Transcription" "Cluster 39: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 7 "Intermediate filaments" "HPA003201: " "unprognostic (2.26e-1)" "unprognostic (6.76e-2)" "unprognostic (5.33e-2)" "unprognostic (8.01e-3)" "unprognostic (5.32e-2)" "unprognostic (1.70e-1)" "unprognostic (8.98e-2)" "unprognostic (3.37e-2)" "unprognostic (2.22e-2)" "potential prognostic unfavorable (1.89e-4)" "unprognostic (2.42e-3)" "unprognostic (8.42e-2)" "unprognostic (2.49e-2)" "potential prognostic unfavorable (5.47e-6)" "unprognostic (1.14e-2)" "unprognostic (1.56e-1)" "unprognostic (2.03e-2)" "unprognostic (4.57e-2)" "unprognostic (8.83e-3)" "unprognostic (2.39e-1)" "unprognostic (2.93e-1)" "unprognostic (6.79e-2)" "potential prognostic unfavorable (7.20e-4)" "unprognostic (1.86e-1)" "unprognostic (2.98e-2)" "unprognostic (7.37e-2)" "unprognostic (1.95e-1)" "unprognostic (2.69e-1)" "unprognostic (1.23e-1)" "unprognostic (2.30e-3)" "unprognostic (1.45e-1)" ZKSCAN7 "FLJ12738, ZNF167, ZNF448, ZNF64, ZSCAN39" ENSG00000196345 "Zinc finger with KRAB and SCAN domains 7" Q9P0L1 3 44555193-44594173 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 8.5;Bergmann glia: 11.6;Brain excitatory neurons: 6.9;Brain inhibitory neurons: 6.7;Choroid plexus epithelial cells: 9.9;Distal convoluted tubule cells: 9.6;Ependymal cells: 6.9;Late primary spermatocytes: 9.5;Late spermatids: 22.4;Loop of henle epithelial cells: 10.0;Microglia: 5.9;Oligodendrocyte progenitor cells: 12.0;Oligodendrocytes: 9.7;Other brain neurons: 6.6;Podocytes: 6.2;Proximal tubule cells: 7.6;Renal collecting duct intercalated cells: 7.1;Renal collecting duct principal cells: 6.9;Renal connecting tubule cells: 8.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 2.9;testis cancer: 2.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048312, HPA049906, HPA071850" Uncertain Supported "Nuclear speckles,Cytosol" NA NA "Cluster 21: Testis - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 102: Non-specific - Mixed function" 5 Cytosol "Nuclear speckles" "HPA048312: , HPA049906: , HPA071850: " "unprognostic (3.84e-2)" "unprognostic (7.14e-2)" "unprognostic (2.23e-1)" "unprognostic (1.93e-1)" "potential prognostic favorable (7.78e-4)" "unprognostic (3.55e-1)" "unprognostic (1.30e-1)" "unprognostic (1.05e-1)" "unprognostic (1.27e-1)" "unprognostic (4.92e-2)" "unprognostic (9.75e-2)" "unprognostic (3.50e-3)" "unprognostic (5.07e-2)" "unprognostic (6.86e-2)" "unprognostic (2.24e-2)" "unprognostic (3.39e-1)" ZKSCAN8 "LD5-1, ZNF192, ZSCAN40" ENSG00000198315 "Zinc finger with KRAB and SCAN domains 8" Q15776 6 28141883-28159460 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003483 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 32: Basophils - Transcription" "Cluster 49: Non-specific - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 28: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" 31 Nucleoplasm Cytosol "HPA003483: " "unprognostic (2.65e-3)" "unprognostic (2.91e-1)" "unprognostic (8.10e-2)" "unprognostic (1.45e-1)" "unprognostic (6.00e-2)" "unprognostic (1.19e-2)" "unprognostic (9.14e-2)" "unprognostic (3.98e-2)" "unprognostic (2.68e-2)" "unprognostic (4.55e-3)" "unprognostic (4.60e-3)" "unprognostic (2.40e-1)" "unprognostic (6.46e-3)" "unprognostic (8.78e-2)" "unprognostic (1.04e-1)" "unprognostic (1.29e-1)" "unprognostic (6.88e-3)" "unprognostic (1.07e-1)" "unprognostic (1.46e-2)" "unprognostic (1.86e-1)" "unprognostic (5.29e-2)" "unprognostic (2.46e-1)" "potential prognostic favorable (6.65e-4)" "unprognostic (1.18e-1)" "unprognostic (1.66e-2)" "unprognostic (1.27e-1)" "unprognostic (8.28e-2)" "unprognostic (5.31e-2)" "unprognostic (1.38e-1)" ZKSCAN8P1 "dJ265C24.4, ZNF192P1, ZNF389, ZNF389P" ENSG00000226314 "ZKSCAN8 pseudogene 1" 6 28161769-28169594 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 5.7;Bergmann glia: 7.0;Early spermatids: 6.7;Epididymal clear cells: 8.2;Epididymal principal cells: 6.4;Late primary spermatocytes: 7.8;Myonuclei: 5.6;Tuft cells: 11.5" "Low cell type specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" "Low region specificity" "Detected in all" NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 53: Neurons - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" ZMAT1 KIAA1789 ENSG00000166432 "Zinc finger matrin-type 1" Q5H9K5 X 101882288-101932031 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 202.8;Corticotrophs: 181.0;Ependymal cells: 245.3;Lactotrophs: 211.4;Pituicytes/FSCs: 325.5;Pituitary stem cells: 221.5;Podocytes: 200.3;Somatotrophs: 263.7;Thyrotrophs: 242.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012827 Enhanced Approved Nucleoplasm NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 70: Non-specific - Protein processing" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 3 Nucleoplasm "HPA012827: " "unprognostic (3.10e-2)" "unprognostic (5.82e-3)" "unprognostic (9.16e-2)" "potential prognostic favorable (1.92e-5)" "unprognostic (1.66e-1)" "unprognostic (5.88e-2)" "unprognostic (2.40e-1)" "potential prognostic unfavorable (1.16e-4)" "unprognostic (4.30e-2)" "unprognostic (5.15e-2)" "unprognostic (1.33e-3)" "unprognostic (2.81e-3)" "unprognostic (3.63e-3)" "unprognostic (6.51e-2)" "unprognostic (2.64e-2)" "unprognostic (2.21e-2)" "unprognostic (1.70e-1)" "unprognostic (1.18e-2)" "potential prognostic favorable (1.11e-6)" "unprognostic (5.91e-2)" "unprognostic (7.47e-3)" "unprognostic (6.81e-3)" "unprognostic (1.33e-1)" "unprognostic (1.76e-1)" "unprognostic (1.29e-1)" ZMAT2 "FLJ31121, hSNU23, Snu23" ENSG00000146007 "Zinc finger matrin-type 2" Q96NC0 5 140698680-140706686 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 370.9;Syncytiotrophoblasts: 249.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036518 Approved Approved Nucleoplasm,Mitochondria NA NA 11000 "Cluster 21: Neutrophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 64 "Nucleoplasm, Mitochondria" "HPA036518: " "unprognostic (2.41e-1)" "unprognostic (1.50e-1)" "unprognostic (2.40e-2)" "unprognostic (2.70e-1)" "unprognostic (2.10e-1)" "unprognostic (3.82e-1)" "unprognostic (3.26e-1)" "unprognostic (7.25e-2)" "potential prognostic unfavorable (6.22e-4)" "unprognostic (4.79e-2)" "potential prognostic favorable (1.12e-6)" "unprognostic (3.60e-2)" "unprognostic (7.28e-2)" "potential prognostic unfavorable (2.85e-4)" "unprognostic (1.29e-2)" "unprognostic (4.20e-3)" "unprognostic (1.61e-1)" "unprognostic (6.85e-2)" "unprognostic (7.98e-2)" "unprognostic (7.56e-2)" "unprognostic (2.08e-2)" "unprognostic (1.47e-2)" "unprognostic (9.58e-3)" "unprognostic (1.12e-1)" "unprognostic (9.82e-2)" "unprognostic (7.27e-2)" "unprognostic (1.71e-1)" "unprognostic (5.48e-2)" "unprognostic (1.12e-2)" "unprognostic (1.42e-1)" "unprognostic (3.58e-2)" ZMAT3 "FLJ12296, MGC10613, PAG608, WIG-1, WIG1" ENSG00000172667 "Zinc finger matrin-type 3" Q9HA38 3 178960121-179072215 "Predicted intracellular proteins" "Apoptosis, DNA damage, Growth regulation, Protein transport, Translocation, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bergmann glia: 128.2;Microglia: 169.2;Oligodendrocyte progenitor cells: 187.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027569, HPA028671, HPA054356" Enhanced Supported Nucleoplasm NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 36: Brain & Liver - Signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 40: Non-specific - Unknown function" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 9 Nucleoplasm "HPA027569: , HPA028671: , HPA054356: " "unprognostic (2.42e-1)" "unprognostic (4.91e-3)" "unprognostic (2.50e-1)" "unprognostic (5.08e-2)" "unprognostic (7.71e-2)" "unprognostic (1.89e-1)" "unprognostic (2.40e-1)" "potential prognostic unfavorable (1.16e-5)" "unprognostic (1.31e-1)" "unprognostic (2.66e-1)" "unprognostic (1.98e-3)" "unprognostic (1.96e-3)" "unprognostic (3.37e-2)" "unprognostic (2.19e-1)" "unprognostic (5.95e-2)" "unprognostic (3.65e-2)" "potential prognostic unfavorable (1.05e-4)" "unprognostic (2.11e-1)" "unprognostic (3.19e-2)" "unprognostic (1.32e-1)" "potential prognostic unfavorable (2.22e-5)" "unprognostic (3.83e-2)" "unprognostic (1.11e-1)" "unprognostic (3.47e-1)" "unprognostic (1.26e-1)" "unprognostic (3.79e-3)" "unprognostic (1.44e-1)" "unprognostic (1.67e-1)" "unprognostic (1.10e-1)" "unprognostic (1.08e-1)" "unprognostic (7.45e-2)" ZMAT4 FLJ13842 ENSG00000165061 "Zinc finger matrin-type 4" Q9H898 8 40530590-40897833 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 12.9;retina: 4.1;thyroid gland: 15.3" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 151.0;Brain inhibitory neurons: 394.5;Late spermatids: 88.1;Medullary thymic epithelial cells: 158.4;Other brain neurons: 221.7;Retinal amacrine cells: 525.5;Retinal ganglion cells: 448.1;Somatotrophs: 131.8;Thyrotrophs: 165.4;Tuft cells: 230.6" "Cell type enhanced" "Detected in many" "midbrain-derived inhibitory: 1206.1" "Cancer enhanced" "Detected in some" "Kidney Renal Clear Cell Carcinoma (TCGA): 3.2;Thyroid Carcinoma (TCGA): 4.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 86 "NK-cell: 8.6" "Lineage enriched" "Detected in single" 86 "NK-cells: 8.6" "Cancer enhanced" "Detected in some" "Neuroblastoma: 6.9" "Adrenal gland - Adrenal medulla cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069813, HPA071585" Enhanced Approved Nucleoplasm,Nucleoli No NA "Cluster 15: NK-cells - Unknown function" "Cluster 78: Brain - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 109: Neurons - Neuronal signaling" 2 "Nucleoplasm, Nucleoli" "HPA069813: , HPA071585: " "unprognostic (2.14e-2)" "unprognostic (2.22e-1)" "unprognostic (2.14e-1)" "unprognostic (9.45e-2)" "unprognostic (8.84e-2)" "unprognostic (5.19e-1)" "potential prognostic unfavorable (1.37e-4)" ZMAT5 "SNRNP20, ZC3H19" ENSG00000100319 "Zinc finger matrin-type 5" Q9UDW3 22 29730956-29767011 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 104.3;Esophageal apical cells: 168.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004858 Approved Supported Nucleoplasm NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" 22 Nucleoplasm "HPA004858: " "unprognostic (1.49e-1)" "unprognostic (4.37e-1)" "unprognostic (3.48e-2)" "unprognostic (2.44e-2)" "unprognostic (2.90e-1)" "unprognostic (2.65e-2)" "unprognostic (5.03e-2)" "unprognostic (1.88e-1)" "potential prognostic favorable (5.60e-4)" "unprognostic (4.98e-3)" "unprognostic (3.39e-1)" "unprognostic (4.08e-2)" "unprognostic (1.23e-2)" "unprognostic (5.37e-3)" "potential prognostic unfavorable (1.36e-4)" "unprognostic (3.02e-1)" "unprognostic (1.89e-1)" "unprognostic (5.43e-2)" "unprognostic (3.22e-1)" "unprognostic (2.20e-1)" "unprognostic (1.45e-1)" "unprognostic (1.53e-1)" "unprognostic (3.53e-2)" "unprognostic (1.16e-2)" "unprognostic (5.85e-2)" "unprognostic (4.47e-3)" "unprognostic (2.43e-1)" "unprognostic (2.48e-2)" "unprognostic (1.48e-1)" "unprognostic (1.59e-1)" "unprognostic (1.91e-1)" ZMIZ1 "FLJ13541, hZIMP10, KIAA1224, MIZ, RAI17, RP11-519K18.1, Zimp10" ENSG00000108175 "Zinc finger MIZ-type containing 1" Q9ULJ6 10 79068966-79316519 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 371.5;Late spermatids: 426.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045144, HPA071156" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 19: Astrocytes - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 6 Nucleoplasm Cytosol "HPA045144: , HPA071156: " "unprognostic (4.57e-3)" "potential prognostic unfavorable (1.72e-4)" "unprognostic (1.45e-1)" "unprognostic (1.52e-2)" "unprognostic (6.89e-2)" "unprognostic (7.51e-2)" "unprognostic (3.40e-1)" "unprognostic (6.30e-2)" "unprognostic (6.42e-2)" "unprognostic (8.38e-2)" "potential prognostic favorable (2.80e-4)" "unprognostic (2.48e-2)" "unprognostic (6.71e-3)" "unprognostic (2.55e-2)" "unprognostic (1.17e-1)" "unprognostic (1.82e-1)" "unprognostic (2.38e-1)" "unprognostic (5.42e-2)" "unprognostic (3.15e-2)" "unprognostic (5.03e-3)" "unprognostic (9.86e-2)" "unprognostic (4.00e-2)" "unprognostic (3.60e-2)" "unprognostic (2.63e-1)" "unprognostic (3.47e-1)" "unprognostic (4.36e-2)" "unprognostic (1.67e-2)" "unprognostic (7.18e-2)" "unprognostic (3.86e-1)" "unprognostic (2.14e-1)" "unprognostic (1.99e-1)" ZMIZ2 "DKFZp761I2123, hZIMP7, KIAA1886, NET27, ZIMP7" ENSG00000122515 "Zinc finger MIZ-type containing 2" Q8NF64 7 44748581-44769881 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 156.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040716, HPA071991" Supported Supported Nucleoplasm,Mitochondria No No "Cluster 32: Basophils - Transcription" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 51: Neurons - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 82: Dendritic cells - Antigen presentation" 5 Nucleoplasm Mitochondria "HPA040716: , HPA071991: " "unprognostic (2.41e-3)" "unprognostic (1.63e-1)" "unprognostic (1.29e-1)" "unprognostic (5.76e-2)" "unprognostic (1.24e-1)" "unprognostic (1.59e-1)" "unprognostic (3.54e-1)" "unprognostic (3.40e-1)" "unprognostic (1.85e-3)" "unprognostic (2.85e-2)" "potential prognostic favorable (9.23e-4)" "unprognostic (4.88e-2)" "unprognostic (1.62e-2)" "potential prognostic unfavorable (8.01e-4)" "unprognostic (1.25e-1)" "unprognostic (1.31e-2)" "unprognostic (5.65e-2)" "unprognostic (3.48e-2)" "unprognostic (1.42e-1)" "unprognostic (1.68e-1)" "unprognostic (1.01e-2)" "unprognostic (1.02e-1)" "potential prognostic unfavorable (8.05e-4)" "unprognostic (1.68e-1)" "unprognostic (2.41e-2)" "unprognostic (3.60e-3)" "unprognostic (2.87e-1)" "unprognostic (4.50e-1)" "unprognostic (1.69e-1)" "unprognostic (8.63e-2)" "unprognostic (1.40e-1)" ZMPSTE24 "FACE-1, HGPS, PRO1, STE24, Ste24p" ENSG00000084073 "Zinc metallopeptidase STE24" O75844 1 40258041-40294180 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Antiviral protein, Hydrolase, Metalloprotease, Protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006988 Approved NA NA 26000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 37: Non-specific - mRNA processing" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 32 "HPA006988: " "unprognostic (1.32e-2)" "unprognostic (1.42e-2)" "unprognostic (4.54e-3)" "unprognostic (2.33e-2)" "potential prognostic favorable (1.91e-4)" "unprognostic (1.06e-1)" "unprognostic (4.50e-2)" "unprognostic (8.79e-3)" "unprognostic (1.22e-1)" "unprognostic (6.97e-2)" "potential prognostic favorable (1.12e-6)" "unprognostic (2.40e-1)" "unprognostic (9.28e-2)" "potential prognostic unfavorable (4.00e-5)" "unprognostic (2.53e-3)" "unprognostic (2.60e-1)" "unprognostic (1.11e-1)" "unprognostic (1.16e-1)" "unprognostic (1.37e-1)" "unprognostic (2.81e-2)" "potential prognostic unfavorable (7.98e-4)" "unprognostic (6.61e-2)" "unprognostic (3.45e-1)" "unprognostic (1.59e-1)" "unprognostic (2.93e-1)" "unprognostic (1.81e-1)" "unprognostic (1.15e-1)" "unprognostic (3.30e-1)" "unprognostic (2.65e-1)" "unprognostic (1.89e-2)" "unprognostic (3.14e-1)" ZMYM1 "FLJ23151, MYM" ENSG00000197056 "Zinc finger MYM-type containing 1" Q5SVZ6 1 35032172-35115859 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064019 Approved "Nucleoplasm,Centriolar satellite" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 37: Non-specific - mRNA processing" "Cluster 7: Non-specific - Transcription" 6 "Centriolar satellite" Nucleoplasm "HPA064019: " "unprognostic (5.04e-3)" "unprognostic (6.28e-2)" "unprognostic (4.68e-2)" "unprognostic (3.29e-3)" "unprognostic (9.64e-2)" "unprognostic (4.17e-2)" "unprognostic (4.14e-2)" "unprognostic (3.12e-2)" "unprognostic (1.49e-1)" "unprognostic (7.75e-3)" "potential prognostic favorable (7.29e-4)" "unprognostic (1.68e-1)" "unprognostic (2.11e-1)" "unprognostic (6.12e-3)" "unprognostic (2.74e-3)" "unprognostic (2.83e-2)" "unprognostic (5.39e-2)" "unprognostic (7.18e-2)" "unprognostic (3.21e-1)" "unprognostic (1.72e-1)" "unprognostic (1.88e-1)" "unprognostic (1.57e-1)" "unprognostic (3.14e-2)" "unprognostic (2.57e-1)" "potential prognostic favorable (4.06e-4)" "unprognostic (4.09e-2)" "unprognostic (5.51e-1)" "unprognostic (2.85e-2)" "unprognostic (1.10e-1)" "unprognostic (1.43e-2)" "unprognostic (1.34e-1)" ZMYM2 "FIM, MYM, RAMP, ZNF198" ENSG00000121741 "Zinc finger MYM-type containing 2" Q9UBW7 13 19958677-20091829 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031765 Approved Supported "Nucleoplasm,Endoplasmic reticulum,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 40: Non-specific - Mixed function" "Cluster 34: Non-specific - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 103: Non-specific - Basic cellular processes" 62 Nucleoplasm "Endoplasmic reticulum, Cytosol" "HPA031765: " "unprognostic (5.11e-3)" "unprognostic (1.17e-2)" "unprognostic (1.44e-1)" "unprognostic (1.56e-2)" "unprognostic (7.25e-2)" "unprognostic (2.65e-2)" "unprognostic (1.83e-1)" "potential prognostic favorable (3.80e-6)" "unprognostic (3.14e-1)" "potential prognostic unfavorable (2.11e-4)" "potential prognostic favorable (1.92e-5)" "unprognostic (3.11e-2)" "unprognostic (1.17e-2)" "unprognostic (3.39e-2)" "unprognostic (2.26e-1)" "unprognostic (1.16e-1)" "unprognostic (1.00e-1)" "unprognostic (8.77e-2)" "unprognostic (2.93e-1)" "unprognostic (1.84e-2)" "unprognostic (2.63e-1)" "unprognostic (3.57e-2)" "unprognostic (8.76e-3)" "unprognostic (1.05e-1)" "unprognostic (4.96e-2)" "unprognostic (2.74e-1)" "unprognostic (7.15e-2)" "unprognostic (1.60e-1)" "unprognostic (2.54e-1)" "unprognostic (7.39e-3)" "unprognostic (1.30e-1)" ZMYM3 "DXS6673E, KIAA0385, MYM, ZNF198L2, ZNF261" ENSG00000147130 "Zinc finger MYM-type containing 3" Q14202 X 71239624-71255146 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Autism, Autism spectrum disorder, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ependymal cells: 44.4;Granulosa cells: 41.4;Sertoli cells: 101.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003211, HPA075255" Approved Enhanced Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 75: Ovary - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 36: Non-specific - mRNA processing" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 39 Nucleoplasm "HPA003211: , HPA075255: " "unprognostic (2.08e-2)" "unprognostic (9.07e-2)" "unprognostic (8.55e-2)" "unprognostic (6.18e-2)" "unprognostic (6.15e-2)" "unprognostic (2.54e-1)" "unprognostic (2.03e-1)" "unprognostic (7.59e-2)" "unprognostic (2.71e-1)" "unprognostic (2.97e-3)" "unprognostic (2.62e-2)" "unprognostic (1.22e-1)" "unprognostic (3.56e-1)" "unprognostic (5.85e-3)" "unprognostic (2.12e-3)" "unprognostic (2.26e-1)" "unprognostic (7.25e-2)" "unprognostic (1.24e-1)" "unprognostic (9.73e-3)" "unprognostic (3.82e-1)" "unprognostic (1.58e-1)" "unprognostic (1.70e-1)" "unprognostic (8.84e-3)" "unprognostic (2.63e-1)" "unprognostic (3.38e-3)" "unprognostic (1.97e-1)" "unprognostic (2.07e-2)" "unprognostic (3.63e-1)" "unprognostic (1.35e-1)" "unprognostic (3.81e-2)" "unprognostic (3.34e-1)" ZMYM4 "KIAA0425, MYM, ZNF198L3, ZNF262" ENSG00000146463 "Zinc finger MYM-type containing 4" Q5VZL5 1 35268709-35422058 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Spleen - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051301, HPA054802" Approved Approved Nucleoplasm,Nucleoli,Cytosol No No "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 7: Non-specific - Transcription" 38 Nucleoplasm "Nucleoli, Cytosol" "HPA051301: , HPA054802: " "unprognostic (3.57e-3)" "unprognostic (2.78e-1)" "unprognostic (1.56e-1)" "unprognostic (1.79e-2)" "unprognostic (6.05e-2)" "unprognostic (6.29e-2)" "unprognostic (2.17e-1)" "unprognostic (1.76e-2)" "unprognostic (8.36e-2)" "unprognostic (1.38e-2)" "potential prognostic favorable (6.55e-4)" "unprognostic (1.04e-1)" "unprognostic (2.27e-1)" "potential prognostic unfavorable (8.10e-7)" "unprognostic (1.46e-1)" "unprognostic (1.70e-1)" "unprognostic (3.44e-1)" "unprognostic (9.15e-2)" "unprognostic (1.83e-1)" "unprognostic (4.84e-2)" "unprognostic (4.59e-1)" "unprognostic (3.44e-2)" "unprognostic (2.11e-1)" "unprognostic (5.27e-2)" "unprognostic (3.52e-2)" "unprognostic (3.31e-1)" "unprognostic (1.84e-2)" "unprognostic (1.25e-1)" "unprognostic (9.98e-2)" "unprognostic (6.22e-2)" "unprognostic (1.41e-1)" ZMYM5 "MYM, ZNF198L1, ZNF237" ENSG00000132950 "Zinc finger MYM-type containing 5" Q9UJ78 13 19823482-19863649 "Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015544, HPA020879" Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 20: Non-specific - Transcription regulation" 5 Nucleoplasm "Golgi apparatus" "HPA015544: , HPA020879: " "unprognostic (1.05e-2)" "unprognostic (8.96e-2)" "unprognostic (5.02e-1)" "unprognostic (6.92e-3)" "unprognostic (1.69e-1)" "unprognostic (1.01e-2)" "unprognostic (5.86e-2)" "unprognostic (3.14e-2)" "unprognostic (3.32e-1)" "unprognostic (4.36e-3)" "potential prognostic favorable (2.73e-5)" "unprognostic (2.97e-2)" "unprognostic (8.79e-2)" "unprognostic (1.06e-2)" "unprognostic (1.73e-1)" "unprognostic (7.22e-2)" "potential prognostic unfavorable (8.64e-5)" "unprognostic (1.09e-1)" "unprognostic (1.62e-1)" "unprognostic (1.34e-2)" "unprognostic (4.03e-2)" "unprognostic (4.68e-2)" "unprognostic (8.51e-3)" "unprognostic (6.54e-2)" "unprognostic (8.73e-2)" "unprognostic (3.04e-1)" "unprognostic (2.91e-1)" "unprognostic (1.63e-1)" "unprognostic (9.56e-3)" "unprognostic (5.91e-2)" "unprognostic (3.97e-1)" ZMYM6 "Buster2, KIAA1353, MYM, ZBED7, ZNF198L4, ZNF258" ENSG00000163867 "Zinc finger MYM-type containing 6" O95789 1 34986165-35031945 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 48.9;Bergmann glia: 43.6;Brain excitatory neurons: 42.7;Brain inhibitory neurons: 50.0;Choroid plexus epithelial cells: 44.4;Ependymal cells: 27.1;Microglia: 108.9;Oligodendrocyte progenitor cells: 41.6;Oligodendrocytes: 52.5;Other brain neurons: 38.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011004, HPA071865" Approved Supported Nucleoplasm NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 40: Non-specific - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 22: Non-specific - Basic cellular functions" 7 Nucleoplasm "HPA011004: , HPA071865: " "unprognostic (2.39e-3)" "unprognostic (1.65e-1)" "unprognostic (4.61e-1)" "unprognostic (6.99e-2)" "unprognostic (6.43e-2)" "unprognostic (1.19e-1)" "unprognostic (1.43e-1)" "unprognostic (1.56e-1)" "unprognostic (4.44e-2)" "unprognostic (1.82e-2)" "potential prognostic favorable (6.01e-6)" "unprognostic (9.10e-3)" "unprognostic (5.68e-3)" "potential prognostic unfavorable (3.26e-4)" "unprognostic (9.20e-2)" "unprognostic (1.50e-3)" "unprognostic (1.29e-1)" "unprognostic (4.85e-2)" "unprognostic (2.45e-2)" "unprognostic (3.32e-2)" "unprognostic (2.25e-1)" "unprognostic (1.74e-1)" "unprognostic (4.85e-3)" "unprognostic (1.11e-1)" "unprognostic (4.19e-3)" "unprognostic (1.31e-1)" "unprognostic (1.23e-2)" "unprognostic (2.05e-1)" "unprognostic (1.78e-1)" "unprognostic (8.16e-2)" "unprognostic (1.36e-1)" ZMYND10 "BLU, CILD22, DNAAF7" ENSG00000004838 "Zinc finger MYND-type containing 10" O75800 3 50341110-50345732 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 13 "choroid plexus: 80.2;fallopian tube: 113.1;testis: 226.5" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 129.3;Early spermatids: 234.5;Endometrial ciliated cells: 258.6;Ependymal cells: 149.8;Epididymal efferent duct ciliated cells: 465.0;Fallopian tube ciliated cells: 606.8;Late primary spermatocytes: 1156.1;Late spermatids: 649.7;Respiratory ciliated cells: 611.3" "Cell type enriched" "Detected in many" 5 "ependymal cell: 205.6" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 24.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 1.2" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA035255 Approved "Plasma membrane,Basal body,Cytosol" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" 12 "Plasma membrane, Basal body" Cytosol "HPA035255: " "unprognostic (4.53e-2)" "unprognostic (8.92e-3)" "unprognostic (2.87e-1)" "potential prognostic favorable (9.41e-4)" "unprognostic (2.26e-1)" "unprognostic (3.65e-3)" "unprognostic (7.99e-2)" "unprognostic (2.98e-1)" "potential prognostic favorable (1.17e-5)" "unprognostic (2.54e-1)" "unprognostic (4.08e-2)" "unprognostic (1.77e-1)" "unprognostic (2.21e-1)" "unprognostic (1.53e-1)" "unprognostic (3.48e-1)" "unprognostic (1.27e-2)" "unprognostic (2.91e-2)" "unprognostic (9.51e-3)" "unprognostic (7.70e-2)" "unprognostic (2.19e-1)" "unprognostic (3.63e-2)" "unprognostic (1.47e-1)" ZMYND11 "BRAM1, BS69" ENSG00000015171 "Zinc finger MYND-type containing 11" Q15326 10 130088-254637 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Repressor" "Intellectual disability, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015816 Supported Nucleoplasm NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 33: Thyroid gland - Tissue development" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 7: Non-specific - Transcription" 26 Nucleoplasm "HPA015816: " "unprognostic (1.99e-1)" "unprognostic (1.09e-1)" "unprognostic (2.04e-1)" "unprognostic (8.60e-2)" "unprognostic (1.87e-1)" "unprognostic (1.34e-3)" "unprognostic (9.32e-2)" "potential prognostic favorable (1.44e-4)" "unprognostic (3.51e-2)" "unprognostic (1.73e-1)" "potential prognostic favorable (7.26e-9)" "unprognostic (1.64e-3)" "unprognostic (5.34e-2)" "unprognostic (5.55e-2)" "unprognostic (1.29e-1)" "unprognostic (6.50e-3)" "unprognostic (5.95e-2)" "unprognostic (8.24e-2)" "unprognostic (4.99e-2)" "unprognostic (8.80e-2)" "unprognostic (1.07e-2)" "unprognostic (6.95e-2)" "unprognostic (2.35e-1)" "unprognostic (2.25e-2)" "unprognostic (2.45e-1)" "unprognostic (2.61e-1)" "unprognostic (5.22e-2)" "unprognostic (9.68e-2)" "unprognostic (1.88e-1)" "unprognostic (1.48e-1)" "unprognostic (2.63e-1)" ZMYND12 DKFZp434N2435 ENSG00000066185 "Zinc finger MYND-type containing 12" Q9H0C1 1 42430329-42456253 "Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 16.1;testis: 26.9" "Cell type enhanced" "Detected in many" "Early spermatids: 134.0;Endometrial ciliated cells: 31.6;Epididymal efferent duct ciliated cells: 39.0;Fallopian tube ciliated cells: 47.1;Late primary spermatocytes: 248.9;Late spermatids: 107.4;Respiratory ciliated cells: 53.5" "Cell type enriched" "Detected in many" 4 "ependymal cell: 35.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "prostate cancer: 1.6" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA071608 Approved Nucleoplasm,Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 66 Nucleoplasm Cytosol "HPA071608: " "unprognostic (1.53e-1)" "unprognostic (8.10e-3)" "unprognostic (5.14e-3)" "potential prognostic unfavorable (2.28e-4)" "unprognostic (2.14e-1)" "potential prognostic favorable (1.40e-5)" "unprognostic (2.30e-3)" "unprognostic (8.86e-3)" "unprognostic (9.51e-2)" "unprognostic (5.80e-3)" "unprognostic (1.03e-2)" "unprognostic (5.09e-2)" "unprognostic (2.15e-1)" "unprognostic (1.20e-1)" "unprognostic (2.04e-1)" "unprognostic (6.15e-2)" "unprognostic (3.16e-1)" "potential prognostic favorable (6.53e-4)" "unprognostic (7.13e-2)" "unprognostic (8.50e-2)" "unprognostic (1.13e-1)" "unprognostic (1.17e-1)" "unprognostic (4.71e-2)" ZMYND15 DKFZp434N127 ENSG00000141497 "Zinc finger MYND-type containing 15" Q9H091 17 4739833-4746119 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 25.4" "Group enriched" "Detected in many" 4 "Early spermatids: 196.6;Late primary spermatocytes: 156.4" "Group enriched" "Detected in some" 4 "central nervous system macrophage: 16.1;ependymal cell: 7.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA023286 Approved "Nuclear speckles,Cytosol" NA NA "Cluster 47: Testis - Mixed function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" "Nuclear speckles" Cytosol "HPA023286: " "unprognostic (1.36e-2)" "unprognostic (4.37e-3)" "unprognostic (4.09e-2)" "potential prognostic favorable (1.20e-4)" "unprognostic (1.46e-1)" "unprognostic (1.61e-1)" "unprognostic (1.06e-2)" "unprognostic (1.61e-1)" "unprognostic (6.86e-2)" "unprognostic (3.77e-1)" "unprognostic (9.52e-2)" "unprognostic (2.78e-2)" "potential prognostic favorable (5.91e-5)" "unprognostic (3.17e-2)" "unprognostic (3.06e-2)" "unprognostic (2.38e-3)" "unprognostic (7.38e-3)" "unprognostic (2.63e-1)" "unprognostic (2.75e-1)" "unprognostic (1.26e-1)" "unprognostic (1.12e-1)" "unprognostic (4.74e-3)" "unprognostic (1.81e-1)" "unprognostic (4.93e-1)" "unprognostic (1.37e-2)" "unprognostic (3.70e-1)" "unprognostic (1.21e-2)" "unprognostic (6.78e-2)" "unprognostic (4.55e-2)" "unprognostic (3.12e-1)" "unprognostic (1.58e-2)" ZMYND19 MIZIP ENSG00000165724 "Zinc finger MYND-type containing 19" Q96E35 9 137582081-137590512 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "retina: 267.2" "Group enriched" "Detected in many" 8 "Cone photoreceptor cells: 109.7;Rod photoreceptor cells: 408.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020642, HPA050761" Supported Approved "Golgi apparatus,Vesicles" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 79: Photoreceptor cells - Phototransduction" 64 "Golgi apparatus, Vesicles" "HPA020642: , HPA050761: " "unprognostic (2.65e-2)" "unprognostic (2.62e-2)" "unprognostic (2.49e-2)" "unprognostic (7.70e-2)" "unprognostic (8.75e-2)" "unprognostic (1.49e-2)" "unprognostic (1.14e-1)" "potential prognostic favorable (7.28e-4)" "unprognostic (2.68e-1)" "unprognostic (3.11e-1)" "unprognostic (1.32e-1)" "unprognostic (4.78e-2)" "unprognostic (1.02e-2)" "potential prognostic unfavorable (2.18e-5)" "unprognostic (2.27e-3)" "unprognostic (1.85e-2)" "unprognostic (1.50e-2)" "unprognostic (2.75e-1)" "unprognostic (6.14e-3)" "unprognostic (1.81e-1)" "unprognostic (4.94e-2)" "unprognostic (7.57e-2)" "unprognostic (1.53e-1)" "unprognostic (1.89e-2)" "unprognostic (1.36e-1)" "unprognostic (1.47e-1)" "unprognostic (1.37e-1)" "unprognostic (6.14e-2)" "unprognostic (5.75e-2)" "unprognostic (7.61e-2)" "unprognostic (2.55e-2)" ZMYND8 "KIAA1125, PRKCBP1, RACK7" ENSG00000101040 "Zinc finger MYND-type containing 8" Q9ULU4 20 47209214-47356889 "Disease related genes, Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" "Chromatin regulator" "Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Megakaryocyte-Erythroid progenitors: 597.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020949, HPA051579" Approved Supported Nucleoplasm,Nucleoli NA NA "Cluster 32: Basophils - Transcription" "Cluster 22: Epididymis - Mixed function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 46 Nucleoli Nucleoplasm "HPA020949: , HPA051579: " "unprognostic (1.37e-2)" "unprognostic (1.18e-3)" "unprognostic (4.88e-1)" "potential prognostic unfavorable (6.43e-4)" "unprognostic (1.18e-2)" "unprognostic (1.25e-1)" "unprognostic (1.53e-1)" "unprognostic (2.35e-2)" "unprognostic (1.52e-1)" "unprognostic (5.37e-2)" "unprognostic (1.33e-2)" "unprognostic (1.38e-2)" "unprognostic (4.08e-1)" "potential prognostic unfavorable (9.64e-5)" "unprognostic (4.42e-3)" "unprognostic (3.50e-1)" "unprognostic (3.73e-2)" "unprognostic (2.74e-1)" "unprognostic (1.83e-2)" "unprognostic (1.50e-1)" "unprognostic (1.83e-1)" "unprognostic (2.39e-1)" "unprognostic (1.50e-2)" "unprognostic (1.14e-1)" "unprognostic (8.76e-2)" "unprognostic (3.66e-1)" "unprognostic (1.40e-1)" "unprognostic (1.44e-1)" "unprognostic (8.03e-2)" "unprognostic (1.47e-1)" "unprognostic (4.60e-1)" ZNF10 KOX1 ENSG00000256223 "Zinc finger protein 10" P21506 12 133130575-133159465 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 63.4;Bergmann glia: 62.9;Brain excitatory neurons: 69.8;Brain inhibitory neurons: 74.3;Choroid plexus epithelial cells: 86.5;Ependymal cells: 56.7;Lactotrophs: 31.6;Oligodendrocyte progenitor cells: 67.0;Oligodendrocytes: 59.8;Other brain neurons: 106.7;Somatotrophs: 43.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003204 Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 21: Testis - Mixed function" "Cluster 55: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 22: Non-specific - Basic cellular functions" 5 "Vesicles, Plasma membrane" Nucleoplasm "HPA003204: " "unprognostic (2.73e-2)" "unprognostic (1.70e-1)" "unprognostic (3.21e-1)" "unprognostic (2.17e-1)" "unprognostic (3.28e-2)" "unprognostic (1.06e-1)" "unprognostic (1.79e-1)" "unprognostic (5.33e-2)" "unprognostic (2.12e-3)" "unprognostic (4.22e-1)" "unprognostic (2.30e-2)" "unprognostic (1.19e-2)" "unprognostic (1.39e-3)" "unprognostic (2.08e-1)" "unprognostic (9.62e-3)" "unprognostic (1.00e-2)" "unprognostic (3.50e-1)" "unprognostic (2.55e-1)" "unprognostic (1.49e-1)" "unprognostic (5.37e-2)" "unprognostic (3.27e-1)" "unprognostic (3.05e-3)" "unprognostic (5.60e-2)" "unprognostic (2.62e-2)" "unprognostic (7.28e-2)" "unprognostic (2.43e-1)" "unprognostic (1.63e-2)" "unprognostic (2.50e-1)" "unprognostic (1.23e-1)" "unprognostic (9.12e-2)" "unprognostic (2.59e-1)" ZNF100 ENSG00000197020 "Zinc finger protein 100" Q8IYN0 19 21722771-21767579 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 31.8;Bergmann glia: 43.8;Brain excitatory neurons: 28.7;Choroid plexus epithelial cells: 30.8;Distal convoluted tubule cells: 29.7;Early spermatids: 34.4;Ependymal cells: 36.0;Microglia: 93.6;Oligodendrocyte progenitor cells: 50.6;Oligodendrocytes: 52.1;Papillary tip epithelial cells: 33.7;Renal collecting duct intercalated cells: 38.4;Renal collecting duct principal cells: 41.5;Renal connecting tubule cells: 71.6" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 12.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" HPA059135 Uncertain NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 25: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 4 "HPA059135: " "unprognostic (3.94e-2)" "unprognostic (7.83e-2)" "unprognostic (4.77e-2)" "unprognostic (3.89e-2)" "unprognostic (2.01e-1)" "unprognostic (9.61e-2)" "unprognostic (1.12e-1)" "unprognostic (2.85e-3)" "unprognostic (3.77e-3)" "unprognostic (1.16e-2)" "potential prognostic favorable (4.69e-4)" "unprognostic (1.59e-1)" "unprognostic (1.07e-1)" "unprognostic (1.21e-1)" "unprognostic (7.60e-3)" "unprognostic (2.62e-1)" "unprognostic (1.04e-2)" "unprognostic (3.11e-2)" "unprognostic (7.31e-2)" "unprognostic (5.35e-3)" "unprognostic (2.16e-1)" "unprognostic (2.57e-2)" "unprognostic (2.66e-1)" "unprognostic (1.31e-3)" "unprognostic (3.38e-2)" "unprognostic (6.96e-2)" "unprognostic (3.04e-2)" "unprognostic (3.10e-1)" "unprognostic (4.37e-2)" "unprognostic (1.80e-1)" ZNF101 "DKFZp570I0164, HZF12" ENSG00000181896 "Zinc finger protein 101" Q8IZC7 19 19668796-19683509 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 25.7" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 67.5;T-cells: 47.3" "Cell type enhanced" "Detected in all" "leukocyte: 24.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Spleen - B-cells (Spleen), Testis - Early spermatids" "HPA023449, HPA055486" Uncertain NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" 8 "HPA023449: , HPA055486: " "unprognostic (1.95e-2)" "unprognostic (2.32e-1)" "unprognostic (1.10e-1)" "unprognostic (1.07e-1)" "unprognostic (4.66e-1)" "unprognostic (2.54e-2)" "unprognostic (3.11e-1)" "unprognostic (9.15e-2)" "potential prognostic favorable (2.28e-4)" "unprognostic (2.20e-3)" "unprognostic (5.57e-3)" "unprognostic (4.85e-2)" "unprognostic (1.70e-1)" "unprognostic (1.65e-1)" "unprognostic (1.09e-1)" "potential prognostic favorable (3.20e-4)" "unprognostic (1.69e-1)" "unprognostic (1.67e-1)" "unprognostic (5.67e-3)" "unprognostic (5.56e-2)" "unprognostic (2.91e-1)" "unprognostic (1.22e-1)" "unprognostic (7.65e-3)" "unprognostic (2.21e-2)" "unprognostic (4.91e-3)" "potential prognostic favorable (2.71e-4)" "unprognostic (8.51e-2)" "potential prognostic favorable (4.55e-5)" "unprognostic (1.18e-1)" "unprognostic (1.89e-1)" "unprognostic (8.04e-2)" ZNF106 "SH3BP3, ZFP106, ZNF474" ENSG00000103994 "Zinc finger protein 106" Q9H2Y7 15 42412823-42491141 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 10 "heart muscle: 164.3;skeletal muscle: 367.4;tongue: 435.1" "Cell type enhanced" "Detected in all" "Choroid plexus epithelial cells: 394.9;Melanocytes: 382.5;Myonuclei: 710.0;Neutrophils: 457.3;Thymic myoid cells: 390.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 56.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 161.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054267 Approved Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 36: Choroid plexus - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 4 Nucleoli "Nucleoplasm, Cytosol" "HPA054267: " "unprognostic (4.07e-3)" "unprognostic (1.90e-2)" "unprognostic (5.37e-2)" "unprognostic (4.14e-2)" "unprognostic (8.81e-2)" "unprognostic (1.09e-1)" "unprognostic (2.12e-1)" "unprognostic (2.02e-1)" "potential prognostic unfavorable (3.15e-4)" "validated prognostic favorable (4.35e-7)" "validated prognostic favorable (3.13e-4)" "unprognostic (8.11e-2)" "unprognostic (4.81e-2)" "unprognostic (8.15e-2)" "unprognostic (9.76e-2)" "unprognostic (1.73e-3)" "unprognostic (2.26e-2)" "unprognostic (3.32e-2)" "unprognostic (6.88e-3)" "unprognostic (2.65e-1)" "unprognostic (4.57e-1)" "unprognostic (1.10e-1)" "unprognostic (3.70e-2)" "unprognostic (1.20e-1)" "unprognostic (4.25e-1)" "unprognostic (1.17e-1)" "unprognostic (5.82e-1)" "unprognostic (2.19e-1)" "unprognostic (9.03e-2)" ZNF107 "smap-7, ZFD25, ZNF588" ENSG00000196247 "Zinc finger protein 107" Q9UII5 7 64666099-64711577 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 10.0" "Cell type enhanced" "Detected in many" "B-cells: 108.9;Breast lactating cells: 94.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "lymphoma: 16.8" "Breast - Breast glandular cells, Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 55: Non-specific - Transcription" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 1 "unprognostic (2.41e-1)" "unprognostic (2.91e-1)" "unprognostic (3.24e-1)" "unprognostic (8.15e-2)" "unprognostic (2.05e-2)" "unprognostic (4.04e-2)" "unprognostic (3.02e-1)" "unprognostic (2.29e-1)" "unprognostic (1.74e-2)" "unprognostic (2.28e-3)" "unprognostic (1.34e-2)" "unprognostic (7.35e-2)" "unprognostic (2.15e-1)" "unprognostic (7.93e-3)" "unprognostic (1.54e-1)" "unprognostic (1.82e-1)" "unprognostic (4.91e-3)" "unprognostic (6.16e-2)" "unprognostic (2.97e-1)" "unprognostic (6.83e-2)" "unprognostic (5.58e-3)" "unprognostic (4.00e-1)" "unprognostic (2.35e-2)" "unprognostic (3.53e-2)" "unprognostic (2.10e-2)" "unprognostic (3.02e-1)" "unprognostic (1.97e-2)" "unprognostic (4.91e-1)" "unprognostic (1.73e-1)" "unprognostic (1.09e-1)" "unprognostic (1.77e-2)" ZNF112 "ZFP112, ZNF228" ENSG00000062370 "Zinc finger protein 112" Q9UJU3 19 44326555-44367217 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 14.4;Bergmann glia: 19.3;Brain excitatory neurons: 18.2;Brain inhibitory neurons: 15.8;Choroid plexus epithelial cells: 22.1;Ependymal cells: 14.6;Oligodendrocyte progenitor cells: 17.9;Oligodendrocytes: 19.0;Other brain neurons: 14.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023856, HPA076887" Approved Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 65: Brain - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 2: Cerebellar granular cells - Neuronal signaling" Nucleoplasm "Nucleoli fibrillar center" "HPA023856: , HPA076887: " "unprognostic (3.41e-1)" "unprognostic (4.01e-1)" "unprognostic (9.21e-2)" "unprognostic (3.61e-1)" "unprognostic (5.67e-2)" "unprognostic (5.86e-2)" "unprognostic (1.28e-1)" "unprognostic (3.40e-1)" "unprognostic (6.14e-3)" "potential prognostic favorable (3.67e-5)" "unprognostic (5.74e-3)" "unprognostic (2.60e-1)" "unprognostic (2.13e-2)" "unprognostic (6.47e-2)" "unprognostic (1.81e-1)" "unprognostic (5.52e-2)" "unprognostic (2.84e-1)" "unprognostic (1.54e-1)" "unprognostic (1.25e-2)" "unprognostic (7.08e-2)" "unprognostic (3.02e-2)" "unprognostic (5.59e-3)" "unprognostic (6.49e-3)" "unprognostic (1.30e-1)" "unprognostic (8.83e-2)" "unprognostic (1.17e-2)" "unprognostic (1.89e-1)" "unprognostic (1.98e-1)" "unprognostic (3.84e-1)" ZNF114 MGC17986 ENSG00000178150 "Zinc finger protein 114" Q8NC26 19 48270081-48287608 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "thyroid gland: 5.4" "Cell type enhanced" "Detected in some" "Early spermatids: 14.0;Endometrial ciliated cells: 8.2;Endometrial glandular cells: 9.7;Endometrial luminal cells: 25.6;Extravillous trophoblasts: 6.7;Migrating cytotrophoblasts: 14.9;Syncytiotrophoblasts: 52.6" "Cell type enhanced" "Detected in many" "oligodendrocyte precursor cell: 7.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "HPA025019, HPA029553" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 33: Thyroid gland - Tissue development" "Cluster 15: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 10 "Nucleoplasm, Cytosol" "HPA025019: , HPA029553: " "unprognostic (1.16e-1)" "unprognostic (1.62e-3)" "unprognostic (1.30e-1)" "unprognostic (5.11e-2)" "unprognostic (1.43e-2)" "unprognostic (2.44e-1)" "unprognostic (5.81e-3)" "potential prognostic unfavorable (2.85e-5)" "unprognostic (3.29e-1)" "unprognostic (5.27e-2)" "unprognostic (1.24e-2)" "unprognostic (7.37e-2)" "unprognostic (1.39e-1)" "unprognostic (1.41e-1)" "unprognostic (3.13e-1)" "unprognostic (1.52e-2)" "unprognostic (1.25e-3)" "unprognostic (3.97e-3)" "unprognostic (6.29e-2)" "unprognostic (2.68e-1)" "unprognostic (1.72e-1)" "unprognostic (2.10e-2)" "unprognostic (3.11e-2)" ZNF117 "H-plk, HPF9" ENSG00000152926 "Zinc finger protein 117" Q03924 7 64971772-65006684 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 315.0;Adrenal cortex cells: 108.0;Esophageal apical cells: 122.0;Neutrophils: 112.1;Sertoli cells: 81.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.8" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in all" "testis cancer: 18.9" "Testis - Sertoli cells" HPA031148 Approved "Nucleoli fibrillar center,Cytosol" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 46: Brainstem - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 89: Adipocytes - Lipid metabolism" 1 "Nucleoli fibrillar center, Cytosol" "HPA031148: " "unprognostic (2.39e-1)" "unprognostic (1.08e-1)" "unprognostic (1.74e-2)" "unprognostic (1.34e-3)" "unprognostic (6.32e-3)" "unprognostic (1.36e-1)" "unprognostic (6.99e-2)" "unprognostic (9.04e-2)" "unprognostic (8.05e-3)" "potential prognostic unfavorable (4.86e-5)" "potential prognostic unfavorable (8.64e-6)" "unprognostic (2.35e-3)" "unprognostic (2.35e-1)" "unprognostic (2.51e-1)" "unprognostic (1.25e-1)" "unprognostic (4.38e-2)" "unprognostic (1.97e-1)" "unprognostic (8.72e-2)" "unprognostic (2.18e-1)" "unprognostic (9.14e-2)" "unprognostic (1.35e-1)" "unprognostic (4.84e-2)" "unprognostic (7.82e-3)" "unprognostic (1.86e-1)" "unprognostic (2.14e-1)" "unprognostic (9.47e-3)" "unprognostic (1.78e-1)" "unprognostic (1.58e-1)" "unprognostic (2.66e-1)" "unprognostic (4.37e-1)" ZNF12 "GIOT-3, KOX3, ZNF325" ENSG00000164631 "Zinc finger protein 12" P17014 7 6688433-6706947 "Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 8.7" "Lineage enriched" "Detected in many" 4 "granulocytes: 8.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063402 Supported Nucleoplasm,Centrosome NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 67: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 5 Nucleoplasm Centrosome "HPA063402: " "unprognostic (7.25e-3)" "unprognostic (1.76e-1)" "unprognostic (4.86e-1)" "unprognostic (3.11e-2)" "unprognostic (2.37e-2)" "unprognostic (1.24e-1)" "unprognostic (3.54e-2)" "potential prognostic unfavorable (4.08e-4)" "unprognostic (8.08e-2)" "unprognostic (6.77e-3)" "potential prognostic favorable (1.74e-4)" "unprognostic (1.10e-2)" "unprognostic (1.94e-1)" "unprognostic (1.02e-3)" "unprognostic (2.45e-3)" "unprognostic (1.69e-1)" "unprognostic (8.39e-3)" "unprognostic (1.79e-1)" "unprognostic (6.87e-2)" "unprognostic (4.13e-3)" "potential prognostic unfavorable (2.59e-6)" "unprognostic (1.87e-1)" "unprognostic (2.57e-3)" "unprognostic (6.59e-2)" "unprognostic (3.86e-2)" "unprognostic (3.15e-1)" "unprognostic (5.18e-3)" "unprognostic (8.01e-2)" "unprognostic (3.38e-2)" "unprognostic (8.05e-2)" "unprognostic (1.82e-1)" ZNF121 "D19S204, ZHC32, ZNF20" ENSG00000197961 "Zinc finger protein 121" P58317 19 9560329-9584504 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054961 Uncertain Approved Nucleoplasm,Nucleoli,Centrosome NA NA "Cluster 1: T-cells - Unknown function" "Cluster 58: Skin - Keratinization" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 56: Non-specific - Sensory perception" "Cluster 17: Non-specific - RNA processing" 9 "Nucleoplasm, Centrosome" Nucleoli "HPA054961: " "unprognostic (1.51e-2)" "unprognostic (2.00e-1)" "unprognostic (1.93e-1)" "unprognostic (2.44e-1)" "unprognostic (2.33e-1)" "unprognostic (8.32e-2)" "unprognostic (1.74e-2)" "unprognostic (5.85e-2)" "unprognostic (1.72e-2)" "unprognostic (2.24e-2)" "unprognostic (2.51e-2)" "unprognostic (2.87e-2)" "unprognostic (2.18e-1)" "unprognostic (2.30e-2)" "unprognostic (1.48e-1)" "unprognostic (4.07e-2)" "unprognostic (5.67e-2)" "unprognostic (5.66e-2)" "potential prognostic favorable (6.58e-5)" "unprognostic (2.19e-3)" "unprognostic (1.13e-2)" "unprognostic (1.66e-1)" "unprognostic (5.68e-3)" "potential prognostic unfavorable (5.37e-4)" "unprognostic (6.87e-3)" "unprognostic (1.45e-3)" "unprognostic (2.55e-2)" "unprognostic (2.26e-2)" "unprognostic (2.37e-1)" "unprognostic (8.42e-2)" "unprognostic (2.42e-1)" ZNF124 "HZF-16, HZF16" ENSG00000196418 "Zinc finger protein 124" Q15973 1 247121975-247172020 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 6 "Early spermatids: 438.5;Late spermatids: 1605.5" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 140.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" HPA031127 Uncertain Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 2: Neurons - Nucleosome" "Cluster 45: Non-specific - Nuclear processes" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 46 "Nucleoplasm, Nuclear membrane" "HPA031127: " "unprognostic (2.69e-1)" "unprognostic (2.70e-1)" "unprognostic (4.02e-1)" "unprognostic (6.65e-3)" "unprognostic (3.23e-1)" "unprognostic (4.86e-1)" "unprognostic (7.81e-2)" "unprognostic (7.42e-3)" "unprognostic (5.58e-2)" "unprognostic (8.15e-3)" "unprognostic (1.38e-2)" "unprognostic (6.43e-3)" "unprognostic (3.45e-2)" "unprognostic (2.61e-3)" "unprognostic (2.35e-1)" "unprognostic (3.75e-2)" "unprognostic (1.95e-2)" "unprognostic (1.61e-1)" "unprognostic (2.77e-3)" "unprognostic (8.25e-2)" "unprognostic (7.79e-2)" "unprognostic (3.13e-1)" "unprognostic (7.05e-3)" "unprognostic (1.77e-2)" "unprognostic (2.89e-2)" "unprognostic (6.94e-2)" "unprognostic (5.48e-2)" "unprognostic (2.89e-1)" "unprognostic (1.89e-1)" "unprognostic (1.24e-1)" "unprognostic (2.23e-1)" ZNF131 "pHZ-10, ZBTB35" ENSG00000172262 "Zinc finger protein 131" P52739 5 43065176-43192021 "Essential proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007023, HPA027748, HPA074630" Approved Enhanced "Nucleoplasm,Intermediate filaments" No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 16: Non-specific - Transcription" "Cluster 29: Non-specific - Unknown function" "Cluster 103: Non-specific - Basic cellular processes" 11 Nucleoplasm "Intermediate filaments" "HPA007023: , HPA027748: , HPA074630: " "unprognostic (1.76e-1)" "unprognostic (6.84e-3)" "unprognostic (1.31e-1)" "unprognostic (1.91e-1)" "unprognostic (1.42e-2)" "unprognostic (1.59e-3)" "unprognostic (1.42e-1)" "unprognostic (9.31e-3)" "unprognostic (7.42e-2)" "potential prognostic unfavorable (1.35e-4)" "unprognostic (3.04e-1)" "unprognostic (2.22e-1)" "unprognostic (1.10e-1)" "potential prognostic unfavorable (6.96e-6)" "unprognostic (2.63e-1)" "unprognostic (7.94e-2)" "unprognostic (1.13e-2)" "unprognostic (4.90e-2)" "unprognostic (8.55e-2)" "unprognostic (6.20e-2)" "unprognostic (3.87e-1)" "unprognostic (4.36e-2)" "potential prognostic unfavorable (3.18e-4)" "unprognostic (2.59e-2)" "unprognostic (4.02e-2)" "potential prognostic unfavorable (2.99e-4)" "unprognostic (1.86e-2)" "unprognostic (3.93e-2)" "unprognostic (1.53e-1)" "unprognostic (2.25e-3)" "unprognostic (1.52e-1)" ZNF132 pHZ-12 ENSG00000131849 "Zinc finger protein 132" P52740 19 58432814-58440153 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 29.2;Epicardial cells: 11.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" HPA008726 Uncertain Approved "Vesicles,Intermediate filaments" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 2: Neurons - Nucleosome" "Cluster 4: Non-specific - Transcription" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" Vesicles "Intermediate filaments" "HPA008726: " "unprognostic (5.21e-2)" "unprognostic (6.75e-2)" "unprognostic (4.34e-1)" "unprognostic (1.98e-1)" "unprognostic (7.94e-2)" "unprognostic (2.54e-1)" "unprognostic (2.51e-1)" "validated prognostic favorable (1.91e-6)" "validated prognostic favorable (2.36e-4)" "potential prognostic favorable (4.75e-6)" "unprognostic (1.87e-2)" "unprognostic (1.04e-1)" "unprognostic (2.71e-1)" "unprognostic (1.49e-1)" "unprognostic (1.13e-1)" "unprognostic (2.06e-1)" "unprognostic (2.35e-2)" "unprognostic (1.33e-3)" "unprognostic (2.68e-2)" "unprognostic (1.54e-1)" "unprognostic (3.76e-2)" "unprognostic (7.57e-3)" "unprognostic (2.43e-2)" "unprognostic (1.78e-2)" ZNF133 "pHZ-13, pHZ-66, ZNF150" ENSG00000125846 "Zinc finger protein 133" P52736 20 18288283-18316996 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Choroid plexus epithelial cells: 178.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001493 Supported Approved Nucleoplasm,Vesicles NA NA "Cluster 24: Non-specific - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 3 "Nucleoplasm, Vesicles" "HPA001493: " "unprognostic (2.58e-2)" "unprognostic (5.28e-2)" "unprognostic (3.45e-1)" "unprognostic (1.20e-3)" "unprognostic (3.10e-1)" "unprognostic (5.41e-2)" "unprognostic (2.30e-1)" "potential prognostic favorable (8.48e-4)" "unprognostic (3.87e-2)" "unprognostic (3.73e-2)" "unprognostic (6.31e-2)" "unprognostic (1.25e-1)" "unprognostic (1.83e-1)" "potential prognostic unfavorable (1.18e-6)" "unprognostic (1.66e-1)" "unprognostic (6.56e-3)" "unprognostic (2.05e-2)" "unprognostic (2.11e-1)" "unprognostic (1.70e-1)" "unprognostic (2.78e-1)" "unprognostic (1.43e-2)" "potential prognostic favorable (8.61e-4)" "unprognostic (2.52e-2)" "unprognostic (1.58e-1)" "unprognostic (7.92e-2)" "unprognostic (2.67e-3)" "unprognostic (5.09e-2)" "unprognostic (1.14e-1)" "unprognostic (1.17e-1)" "unprognostic (1.16e-1)" "unprognostic (9.48e-2)" ZNF134 pHZ-15 ENSG00000213762 "Zinc finger protein 134" P52741 19 57614233-57624724 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA006341, HPA009064" Supported Enhanced Nucleoplasm NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 61: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 3 Nucleoplasm "HPA006341: , HPA009064: " "unprognostic (2.09e-3)" "unprognostic (3.23e-2)" "unprognostic (1.17e-1)" "potential prognostic unfavorable (5.84e-5)" "unprognostic (1.03e-1)" "unprognostic (1.15e-2)" "unprognostic (2.07e-1)" "unprognostic (9.68e-2)" "potential prognostic unfavorable (8.19e-4)" "unprognostic (4.76e-2)" "validated prognostic favorable (6.20e-6)" "validated prognostic favorable (2.79e-5)" "potential prognostic favorable (9.71e-4)" "unprognostic (3.43e-2)" "unprognostic (1.47e-1)" "unprognostic (1.45e-1)" "unprognostic (3.34e-2)" "unprognostic (2.54e-1)" "unprognostic (3.78e-2)" "unprognostic (2.18e-1)" "unprognostic (1.71e-1)" "unprognostic (5.11e-2)" "unprognostic (1.88e-3)" "unprognostic (7.54e-3)" "unprognostic (1.78e-1)" "unprognostic (1.33e-3)" "unprognostic (2.28e-2)" "unprognostic (1.08e-2)" "unprognostic (1.10e-1)" "unprognostic (1.45e-1)" "unprognostic (3.05e-1)" ZNF135 "pHZ-17, ZNF61, ZNF78L1" ENSG00000176293 "Zinc finger protein 135" P52742 19 58059239-58086310 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 124.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" HPA006961 Approved Approved Cytosol NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 65: Brain - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 4: Non-specific - Transcription" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 2 Cytosol "HPA006961: " "unprognostic (1.78e-3)" "unprognostic (1.39e-2)" "unprognostic (1.42e-2)" "unprognostic (3.06e-1)" "unprognostic (9.10e-2)" "unprognostic (8.39e-2)" "unprognostic (2.13e-1)" "unprognostic (1.46e-3)" "unprognostic (1.40e-3)" "potential prognostic favorable (4.05e-5)" "unprognostic (1.11e-3)" "unprognostic (1.00e-1)" "unprognostic (3.99e-2)" "unprognostic (1.06e-3)" "unprognostic (4.45e-1)" "unprognostic (4.80e-2)" "unprognostic (5.79e-2)" "unprognostic (3.59e-3)" "unprognostic (2.83e-1)" "unprognostic (2.40e-1)" "unprognostic (7.92e-2)" "unprognostic (4.64e-2)" "unprognostic (2.81e-1)" "unprognostic (7.34e-2)" "unprognostic (1.53e-1)" ZNF136 pHZ-20 ENSG00000196646 "Zinc finger protein 136" P52737 19 12163064-12189871 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skeletal muscle - Endothelial cells, Testis - Spermatocytes" HPA054120 Approved Nucleoli NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 12 Nucleoli "HPA054120: " "unprognostic (1.21e-2)" "unprognostic (4.64e-2)" "unprognostic (2.43e-1)" "unprognostic (4.47e-2)" "unprognostic (1.77e-1)" "unprognostic (6.02e-2)" "unprognostic (1.24e-1)" "unprognostic (1.78e-1)" "unprognostic (3.03e-3)" "unprognostic (2.07e-2)" "validated prognostic favorable (9.73e-7)" "validated prognostic favorable (2.54e-4)" "unprognostic (5.08e-3)" "unprognostic (3.78e-1)" "unprognostic (5.07e-2)" "unprognostic (2.78e-3)" "unprognostic (1.55e-1)" "unprognostic (2.39e-1)" "unprognostic (3.93e-2)" "unprognostic (1.08e-1)" "unprognostic (1.27e-1)" "unprognostic (5.19e-3)" "unprognostic (1.58e-2)" "unprognostic (6.07e-3)" "unprognostic (2.14e-2)" "unprognostic (4.25e-2)" "unprognostic (2.72e-2)" "unprognostic (1.54e-1)" "unprognostic (3.64e-1)" "unprognostic (4.70e-1)" "unprognostic (3.38e-1)" ZNF138 pHZ-32 ENSG00000197008 "Zinc finger protein 138" P52744 7 64794388-64833681 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Myonuclei: 128.7" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 24.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 37: Neurons - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 55: Myocytes - Oxidative muscle function" 17 "unprognostic (9.37e-2)" "unprognostic (1.02e-1)" "unprognostic (1.37e-1)" "unprognostic (1.53e-2)" "unprognostic (4.58e-3)" "unprognostic (1.15e-1)" "unprognostic (3.89e-2)" "unprognostic (5.53e-2)" "unprognostic (9.21e-2)" "potential prognostic unfavorable (8.18e-5)" "unprognostic (8.60e-2)" "unprognostic (8.44e-2)" "unprognostic (1.15e-1)" "unprognostic (5.01e-3)" "unprognostic (4.11e-3)" "unprognostic (4.52e-2)" "unprognostic (1.19e-2)" "unprognostic (6.29e-2)" "unprognostic (2.82e-1)" "unprognostic (5.33e-2)" "unprognostic (2.36e-2)" "unprognostic (4.23e-2)" "unprognostic (5.28e-3)" "unprognostic (2.33e-1)" "unprognostic (3.37e-2)" "unprognostic (1.88e-1)" "unprognostic (6.94e-3)" "unprognostic (3.02e-2)" "unprognostic (2.35e-1)" "unprognostic (4.40e-2)" "unprognostic (1.71e-1)" ZNF14 "GIOT-4, KOX6" ENSG00000105708 "Zinc finger protein 14" P17017 19 19710472-19733112 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 53.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA049863 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 6 "Nucleoplasm, Cytosol" "HPA049863: " "unprognostic (8.16e-3)" "unprognostic (1.19e-1)" "unprognostic (1.81e-1)" "unprognostic (1.61e-1)" "unprognostic (1.61e-1)" "unprognostic (9.13e-2)" "unprognostic (1.52e-1)" "unprognostic (1.72e-1)" "unprognostic (1.59e-3)" "unprognostic (3.97e-2)" "potential prognostic favorable (1.91e-9)" "unprognostic (3.52e-3)" "unprognostic (9.10e-2)" "unprognostic (6.26e-2)" "unprognostic (2.30e-1)" "potential prognostic favorable (8.30e-4)" "unprognostic (4.80e-2)" "unprognostic (1.59e-2)" "unprognostic (3.41e-2)" "unprognostic (3.46e-2)" "unprognostic (1.10e-1)" "unprognostic (1.88e-2)" "unprognostic (2.01e-2)" "unprognostic (3.04e-2)" "unprognostic (1.15e-1)" "unprognostic (1.04e-1)" "unprognostic (8.68e-3)" "unprognostic (7.39e-2)" "unprognostic (5.69e-2)" "unprognostic (1.17e-1)" "unprognostic (2.80e-1)" ZNF140 pHZ-39 ENSG00000196387 "Zinc finger protein 140" P52738 12 133080474-133107526 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003655, HPA048332" Uncertain Approved Nucleoplasm NA NA "Cluster 32: Basophils - Transcription" "Cluster 75: Ovary - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 4: Non-specific - Transcription" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 4 Nucleoplasm "HPA003655: , HPA048332: " "unprognostic (1.41e-1)" "unprognostic (3.16e-2)" "unprognostic (1.26e-1)" "unprognostic (1.32e-1)" "unprognostic (1.11e-1)" "unprognostic (6.69e-2)" "unprognostic (1.99e-1)" "unprognostic (1.61e-1)" "unprognostic (1.22e-1)" "unprognostic (6.25e-2)" "unprognostic (1.35e-3)" "potential prognostic favorable (1.28e-4)" "unprognostic (1.66e-1)" "unprognostic (1.23e-1)" "unprognostic (3.71e-1)" "unprognostic (2.20e-1)" "unprognostic (1.40e-2)" "unprognostic (7.76e-2)" "unprognostic (1.02e-1)" "unprognostic (2.36e-1)" "unprognostic (3.97e-1)" "unprognostic (6.53e-2)" "unprognostic (1.91e-1)" "unprognostic (1.34e-1)" "unprognostic (1.08e-2)" "unprognostic (1.56e-1)" "unprognostic (3.78e-2)" "unprognostic (1.29e-1)" "unprognostic (2.75e-1)" "unprognostic (2.61e-2)" "unprognostic (1.57e-1)" ZNF141 "D4S90, pHZ-44" ENSG00000131127 "Zinc finger protein 141" Q15928 4 337814-384868 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Vascular smooth muscle cells: 187.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 64: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 103: Non-specific - Basic cellular processes" "unprognostic (1.67e-3)" "unprognostic (1.15e-1)" "unprognostic (4.78e-3)" "unprognostic (2.98e-1)" "unprognostic (7.43e-2)" "potential prognostic favorable (5.33e-4)" "unprognostic (2.87e-1)" "unprognostic (1.52e-1)" "unprognostic (4.84e-3)" "unprognostic (3.45e-3)" "unprognostic (1.41e-3)" "unprognostic (2.95e-2)" "unprognostic (7.27e-3)" "unprognostic (5.83e-2)" "unprognostic (3.47e-3)" "unprognostic (1.30e-1)" "unprognostic (1.58e-1)" "unprognostic (3.78e-1)" "unprognostic (1.11e-2)" "unprognostic (9.03e-2)" "unprognostic (1.06e-3)" "unprognostic (9.66e-3)" "unprognostic (2.79e-1)" "potential prognostic favorable (9.43e-4)" "unprognostic (3.04e-1)" "unprognostic (5.71e-2)" "unprognostic (3.16e-3)" "unprognostic (3.20e-1)" "unprognostic (7.46e-2)" "unprognostic (6.61e-2)" ZNF142 "KIAA0236, pHZ-49" ENSG00000115568 "Zinc finger protein 142" P52746 2 218633329-218659655 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 51.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049594 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 32: Basophils - Transcription" "Cluster 24: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "Nucleoli fibrillar center" Nucleoplasm "HPA049594: " "unprognostic (2.34e-1)" "unprognostic (2.35e-2)" "unprognostic (6.25e-2)" "unprognostic (7.29e-2)" "unprognostic (7.68e-2)" "unprognostic (1.76e-1)" "unprognostic (3.22e-1)" "unprognostic (2.27e-1)" "unprognostic (1.01e-2)" "unprognostic (5.47e-3)" "unprognostic (2.20e-2)" "unprognostic (4.46e-3)" "unprognostic (2.14e-1)" "potential prognostic unfavorable (2.57e-5)" "unprognostic (9.22e-2)" "unprognostic (2.57e-2)" "unprognostic (6.22e-2)" "unprognostic (7.90e-2)" "unprognostic (1.22e-2)" "unprognostic (2.25e-2)" "unprognostic (6.56e-2)" "unprognostic (1.12e-3)" "unprognostic (5.42e-3)" "unprognostic (2.74e-2)" "unprognostic (2.38e-1)" "unprognostic (5.14e-3)" "unprognostic (3.14e-2)" "unprognostic (9.86e-2)" "unprognostic (5.39e-2)" "unprognostic (6.28e-3)" "unprognostic (1.93e-3)" ZNF143 "pHZ-1, SBF, STAF" ENSG00000166478 "Zinc finger protein 143" P52747 11 9460319-9528524 "Essential proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 183.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003263, HPA003264, HPA074818" Supported Supported "Nucleoplasm,Nuclear bodies,Golgi apparatus,Vesicles" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 65: Non-specific - Cell growth & division" 21 Nucleoplasm "Nuclear bodies, Golgi apparatus, Vesicles" "HPA003263: , HPA003264: , HPA074818: " "unprognostic (2.02e-1)" "unprognostic (7.93e-2)" "unprognostic (3.42e-2)" "potential prognostic unfavorable (1.26e-5)" "unprognostic (4.10e-2)" "unprognostic (6.53e-2)" "unprognostic (1.85e-1)" "unprognostic (2.70e-2)" "unprognostic (1.20e-1)" "potential prognostic unfavorable (4.58e-5)" "validated prognostic favorable (1.41e-4)" "validated prognostic favorable (2.57e-4)" "unprognostic (1.33e-1)" "unprognostic (7.26e-3)" "unprognostic (1.42e-1)" "unprognostic (7.56e-2)" "potential prognostic unfavorable (3.06e-4)" "unprognostic (3.39e-2)" "unprognostic (1.49e-1)" "unprognostic (3.16e-1)" "unprognostic (1.16e-2)" "unprognostic (8.35e-3)" "unprognostic (3.00e-3)" "unprognostic (1.14e-2)" "unprognostic (1.61e-2)" "unprognostic (2.09e-1)" "unprognostic (8.07e-2)" "unprognostic (9.30e-3)" "unprognostic (5.96e-2)" "unprognostic (8.54e-2)" "unprognostic (1.40e-1)" ZNF146 OZF ENSG00000167635 "Zinc finger protein 146" Q15072 19 36214602-36238771 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 222.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003358 Supported Supported Nucleoli NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 2 Nucleoli "HPA003358: " "unprognostic (3.10e-2)" "unprognostic (9.12e-2)" "unprognostic (1.34e-1)" "unprognostic (2.16e-2)" "unprognostic (3.93e-2)" "unprognostic (1.78e-1)" "unprognostic (2.48e-2)" "unprognostic (1.27e-1)" "unprognostic (3.61e-1)" "unprognostic (1.88e-3)" "unprognostic (1.52e-2)" "unprognostic (8.85e-3)" "unprognostic (5.69e-3)" "potential prognostic unfavorable (4.86e-4)" "unprognostic (2.05e-1)" "potential prognostic unfavorable (1.93e-4)" "unprognostic (5.01e-3)" "unprognostic (4.01e-2)" "unprognostic (5.08e-2)" "unprognostic (8.37e-3)" "unprognostic (4.08e-2)" "unprognostic (3.16e-3)" "unprognostic (3.25e-2)" "unprognostic (3.95e-2)" "unprognostic (5.05e-3)" "unprognostic (1.53e-1)" "unprognostic (5.34e-2)" "unprognostic (1.17e-1)" "unprognostic (2.96e-1)" "unprognostic (1.86e-2)" "unprognostic (2.46e-1)" ZNF148 "BERF-1, BFCOL1, HT-BETA, pHZ-52, ZBP-89, ZFP148" ENSG00000163848 "Zinc finger protein 148" Q9UQR1 3 125225669-125375325 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 648.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001656, CAB017486" Supported Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 24: Neutrophils - Innate immunity signal integration" 19 Nucleoplasm "Golgi apparatus" "CAB017486: , HPA001656: " "unprognostic (1.05e-1)" "unprognostic (1.62e-1)" "unprognostic (2.34e-1)" "unprognostic (4.74e-2)" "unprognostic (3.51e-1)" "unprognostic (2.51e-1)" "unprognostic (2.69e-2)" "unprognostic (3.50e-1)" "unprognostic (2.25e-2)" "unprognostic (1.53e-2)" "potential prognostic favorable (7.62e-7)" "unprognostic (1.17e-2)" "unprognostic (1.41e-1)" "unprognostic (3.36e-2)" "unprognostic (8.92e-2)" "unprognostic (2.51e-1)" "unprognostic (6.56e-2)" "unprognostic (1.10e-1)" "unprognostic (2.07e-1)" "unprognostic (1.34e-3)" "potential prognostic unfavorable (3.32e-4)" "unprognostic (1.37e-3)" "unprognostic (5.48e-3)" "unprognostic (6.08e-2)" "unprognostic (2.15e-2)" "unprognostic (1.74e-1)" "unprognostic (5.77e-2)" "unprognostic (4.08e-1)" "unprognostic (3.18e-1)" "unprognostic (2.49e-2)" "unprognostic (5.09e-2)" ZNF154 pHZ-92 ENSG00000179909 "Zinc finger protein 154" Q13106 19 57696275-57709204 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 84.4;Choroid plexus epithelial cells: 22.5;Epicardial cells: 25.0;Somatotrophs: 24.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 2.1" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Rhabdoid: 4.3;testis cancer: 5.6" "Low region specificity" "Detected in all" HPA076284 Approved Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 15: Non-specific - Transcription" "Cluster 59: Leukemia - T-cell receptor" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" "Nucleoplasm, Nucleoli fibrillar center" "HPA076284: " "unprognostic (2.11e-1)" "unprognostic (1.26e-1)" "unprognostic (2.52e-2)" "unprognostic (1.52e-2)" "unprognostic (2.41e-1)" "unprognostic (1.76e-1)" "unprognostic (2.62e-3)" "unprognostic (6.71e-3)" "unprognostic (1.52e-2)" "potential prognostic favorable (8.08e-4)" "unprognostic (7.01e-2)" "unprognostic (1.52e-1)" "unprognostic (4.36e-2)" "unprognostic (5.87e-2)" "unprognostic (2.15e-2)" "unprognostic (2.65e-1)" "unprognostic (1.95e-1)" "unprognostic (2.15e-2)" ZNF155 pHZ-96 ENSG00000204920 "Zinc finger protein 155" Q12901 19 43967862-43998326 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA003220 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 61: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 4 "Nucleoplasm, Cytosol" "HPA003220: " "unprognostic (8.16e-2)" "unprognostic (1.14e-1)" "unprognostic (3.49e-2)" "unprognostic (2.28e-1)" "unprognostic (6.20e-2)" "unprognostic (3.65e-2)" "unprognostic (9.42e-2)" "unprognostic (3.20e-1)" "unprognostic (1.25e-1)" "unprognostic (7.10e-2)" "validated prognostic favorable (2.04e-4)" "validated prognostic favorable (5.57e-4)" "unprognostic (8.11e-3)" "unprognostic (1.62e-1)" "unprognostic (1.81e-2)" "unprognostic (2.89e-1)" "unprognostic (5.73e-2)" "unprognostic (4.71e-2)" "unprognostic (1.25e-1)" "unprognostic (5.11e-2)" "unprognostic (1.58e-1)" "unprognostic (3.20e-2)" "unprognostic (2.36e-1)" "unprognostic (5.37e-2)" "unprognostic (3.66e-2)" "unprognostic (3.56e-1)" "unprognostic (9.74e-3)" "unprognostic (3.90e-1)" "unprognostic (1.74e-1)" "unprognostic (1.37e-1)" "unprognostic (2.83e-1)" ZNF157 HZF22 ENSG00000147117 "Zinc finger protein 157" P51786 X 47370578-47414498 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Corticotrophs: 9.3;Fallopian tube ciliated cells: 9.8;Gonadotrophs: 6.9;Lactotrophs: 7.7;Respiratory ciliated cells: 7.8;Retinal amacrine cells: 9.8;Retinal ganglion cells: 7.7;Somatotrophs: 7.9;Thyrotrophs: 10.4" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in single" "Testicular Germ Cell Tumor (TCGA): 1.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Neuroblastoma: 1.2" "Pituitary gland - Corticotropes" HPA003319 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 16: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" Nucleoplasm Cytosol "HPA003319: " "unprognostic (1.42e-3)" "unprognostic (5.24e-2)" "unprognostic (7.96e-2)" ZNF16 KOX9 ENSG00000170631 "Zinc finger protein 16" P17020 8 144930358-144950888 "Predicted intracellular proteins, Transcription factors" "Cell cycle, Cell division, Transcription, Transcription regulation" "Activator, DNA-binding, Mitogen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Podocytes: 38.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "HPA035782, HPA061835" Uncertain Supported Nucleoplasm,Nucleoli NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 39: Testis - Nuclear processes" "Cluster 17: Choroid plexus - Cilium" "Cluster 40: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 17 Nucleoli Nucleoplasm "HPA035782: , HPA061835: " "potential prognostic favorable (7.42e-4)" "unprognostic (1.34e-2)" "unprognostic (3.04e-1)" "unprognostic (1.32e-1)" "unprognostic (2.37e-1)" "unprognostic (5.81e-2)" "unprognostic (2.94e-1)" "unprognostic (3.57e-1)" "unprognostic (1.26e-3)" "unprognostic (1.29e-1)" "potential prognostic favorable (1.44e-4)" "unprognostic (1.33e-3)" "unprognostic (2.35e-1)" "unprognostic (5.48e-2)" "unprognostic (1.42e-1)" "unprognostic (2.51e-1)" "unprognostic (1.05e-1)" "unprognostic (1.94e-1)" "unprognostic (1.12e-1)" "unprognostic (1.92e-1)" "unprognostic (1.30e-1)" "unprognostic (3.21e-1)" "unprognostic (5.84e-2)" "unprognostic (3.36e-1)" "unprognostic (9.53e-2)" "unprognostic (2.35e-2)" "unprognostic (1.21e-2)" "unprognostic (8.95e-2)" "unprognostic (3.29e-1)" "unprognostic (3.37e-1)" "unprognostic (8.53e-2)" ZNF160 "F11, FLJ00032, HKr18, HZF5, KIAA1611, KR18" ENSG00000170949 "Zinc finger protein 160" Q9HCG1 19 53066606-53103434 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 124.8;Sertoli cells: 122.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Skeletal muscle - Endothelial cells, Spleen - Endothelial cells" HPA023599 Uncertain Approved "Nuclear speckles,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 18: Adrenal cortex cells - Steroidogensis" "Nuclear speckles" Cytosol "HPA023599: " "unprognostic (2.07e-2)" "unprognostic (3.72e-2)" "unprognostic (4.83e-2)" "unprognostic (1.54e-3)" "unprognostic (4.78e-2)" "unprognostic (1.58e-1)" "unprognostic (7.61e-2)" "unprognostic (8.88e-2)" "unprognostic (1.48e-2)" "unprognostic (4.00e-2)" "unprognostic (2.33e-2)" "unprognostic (1.98e-3)" "unprognostic (2.24e-1)" "potential prognostic unfavorable (6.92e-5)" "potential prognostic favorable (2.55e-5)" "unprognostic (6.51e-2)" "unprognostic (1.02e-1)" "unprognostic (4.23e-3)" "unprognostic (1.88e-1)" "unprognostic (1.08e-1)" "unprognostic (1.65e-2)" "unprognostic (1.08e-1)" "unprognostic (5.73e-3)" "unprognostic (3.83e-2)" "unprognostic (4.75e-2)" "unprognostic (1.28e-2)" "unprognostic (1.49e-2)" "unprognostic (2.69e-1)" "unprognostic (4.26e-1)" "unprognostic (1.24e-1)" "unprognostic (3.77e-3)" ZNF165 "CT53, ZSCAN7" ENSG00000197279 "Zinc finger protein 165" P49910 6 28080568-28089563 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 18.5" "Cell type enhanced" "Detected in many" "Colonocytes: 152.0;Early spermatids: 133.7;Epididymal basal cells: 309.7;Epididymal clear cells: 263.3;Epididymal efferent duct ciliated cells: 340.0;Epididymal principal cells: 661.9;Late primary spermatocytes: 149.3;Syncytiotrophoblasts: 133.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Spleen - B-cells (Spleen), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" HPA007247 Approved "Nuclear speckles,Microtubules" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" 40 "Nuclear speckles, Microtubules" "HPA007247: " "unprognostic (2.40e-2)" "unprognostic (3.18e-2)" "unprognostic (3.28e-2)" "unprognostic (1.12e-1)" "unprognostic (6.14e-2)" "unprognostic (1.92e-1)" "unprognostic (4.46e-2)" "unprognostic (2.06e-1)" "unprognostic (2.91e-2)" "unprognostic (1.36e-2)" "validated prognostic favorable (1.13e-5)" "validated prognostic favorable (4.02e-6)" "unprognostic (2.05e-1)" "unprognostic (2.14e-1)" "unprognostic (7.76e-2)" "unprognostic (1.38e-1)" "unprognostic (1.95e-2)" "unprognostic (1.64e-1)" "unprognostic (7.28e-2)" "unprognostic (2.99e-3)" "unprognostic (1.35e-1)" "unprognostic (1.61e-3)" "unprognostic (3.67e-2)" "unprognostic (5.10e-2)" "unprognostic (1.46e-2)" "unprognostic (2.88e-1)" "unprognostic (1.77e-1)" "unprognostic (1.59e-1)" "unprognostic (1.90e-2)" "unprognostic (1.79e-1)" ZNF169 MGC51961 ENSG00000175787 "Zinc finger protein 169" Q14929 9 94259298-94301829 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041769 Uncertain Approved "Nuclear speckles,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Transcription" 6 "Nuclear speckles" Cytosol "HPA041769: " "unprognostic (1.01e-1)" "unprognostic (2.62e-1)" "unprognostic (1.56e-1)" "unprognostic (1.58e-1)" "unprognostic (1.82e-2)" "unprognostic (7.27e-2)" "unprognostic (1.10e-1)" "unprognostic (6.47e-2)" "unprognostic (1.08e-2)" "unprognostic (9.02e-3)" "unprognostic (8.03e-3)" "unprognostic (3.12e-1)" "unprognostic (1.95e-1)" "unprognostic (8.60e-2)" "unprognostic (2.76e-1)" "unprognostic (2.07e-1)" "unprognostic (8.76e-2)" "unprognostic (3.16e-2)" "unprognostic (1.92e-1)" "unprognostic (1.37e-1)" "unprognostic (4.58e-2)" "unprognostic (4.52e-2)" "potential prognostic favorable (2.46e-4)" "unprognostic (1.19e-1)" "unprognostic (1.13e-1)" "unprognostic (4.71e-2)" "unprognostic (1.77e-1)" "unprognostic (6.56e-2)" "unprognostic (1.53e-1)" ZNF17 "FLJ40864, FLJ46058, FLJ46615, HPF3, KIAA1947, KOX10" ENSG00000186272 "Zinc finger protein 17" P17021 19 57411161-57421934 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 12 "potential prognostic favorable (4.61e-4)" "unprognostic (6.55e-2)" "unprognostic (6.64e-2)" "unprognostic (3.21e-1)" "unprognostic (1.60e-1)" "unprognostic (1.99e-2)" "unprognostic (1.77e-1)" "unprognostic (2.68e-1)" "unprognostic (2.93e-2)" "unprognostic (2.38e-1)" "potential prognostic favorable (6.26e-7)" "unprognostic (1.53e-3)" "potential prognostic favorable (8.95e-4)" "unprognostic (8.10e-2)" "unprognostic (2.86e-2)" "unprognostic (3.49e-2)" "unprognostic (1.83e-1)" "unprognostic (3.37e-1)" "unprognostic (7.79e-2)" "unprognostic (4.74e-1)" "unprognostic (4.45e-1)" "unprognostic (6.31e-3)" "unprognostic (1.23e-2)" "unprognostic (2.47e-1)" "unprognostic (2.36e-2)" "unprognostic (1.35e-1)" "unprognostic (5.44e-2)" "unprognostic (1.42e-1)" "unprognostic (1.34e-1)" "unprognostic (6.88e-3)" "unprognostic (3.61e-1)" ZNF174 ZSCAN8 ENSG00000103343 "Zinc finger protein 174" Q15697 16 3401215-3409364 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Early primary spermatocytes: 3.7;Early spermatids: 4.5;Late primary spermatocytes: 9.6;Late spermatids: 3.8;Oocytes: 9.2;Parietal cells: 7.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009656, HPA070692" Approved Supported "Nucleoli fibrillar center,Nuclear bodies" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 9 "Nucleoli fibrillar center" "Nuclear bodies" "HPA009656: , HPA070692: " "unprognostic (1.10e-1)" "unprognostic (2.81e-1)" "unprognostic (9.23e-2)" "unprognostic (3.26e-2)" "unprognostic (3.52e-1)" "unprognostic (1.32e-1)" "unprognostic (5.48e-2)" "unprognostic (3.32e-2)" "unprognostic (3.19e-2)" "unprognostic (4.65e-2)" "potential prognostic favorable (4.37e-4)" "unprognostic (9.92e-2)" "unprognostic (2.55e-1)" "potential prognostic unfavorable (1.62e-5)" "unprognostic (3.82e-3)" "unprognostic (1.18e-1)" "unprognostic (2.47e-1)" "unprognostic (8.50e-2)" "potential prognostic favorable (3.64e-4)" "unprognostic (1.29e-2)" "unprognostic (5.86e-2)" "unprognostic (5.86e-3)" "unprognostic (1.09e-1)" "unprognostic (4.30e-1)" "unprognostic (2.39e-2)" "unprognostic (1.13e-1)" "unprognostic (1.14e-1)" "unprognostic (2.60e-1)" "unprognostic (3.12e-1)" "unprognostic (2.11e-1)" "unprognostic (1.64e-2)" ZNF175 OTK18 ENSG00000105497 "Zinc finger protein 175" Q9Y473 19 51571283-51592510 "Predicted intracellular proteins, Transcription factors" "Antiviral defense, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Platelets: 34.0;Retinal horizontal cells: 40.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002717, HPA074615" Uncertain Supported Nucleoli,Cytosol NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 47: Platelets - Hemostasis" 4 Nucleoli Cytosol "HPA002717: , HPA074615: " "unprognostic (3.61e-3)" "unprognostic (7.50e-2)" "unprognostic (3.33e-3)" "unprognostic (1.58e-3)" "unprognostic (3.33e-1)" "unprognostic (1.91e-3)" "unprognostic (2.71e-1)" "unprognostic (9.15e-2)" "unprognostic (5.39e-3)" "unprognostic (4.77e-2)" "validated prognostic favorable (4.93e-5)" "validated prognostic favorable (5.29e-4)" "unprognostic (4.61e-2)" "unprognostic (1.31e-2)" "unprognostic (1.98e-3)" "unprognostic (1.75e-1)" "unprognostic (5.04e-2)" "unprognostic (1.01e-2)" "unprognostic (4.02e-2)" "unprognostic (4.89e-2)" "unprognostic (3.02e-2)" "unprognostic (5.03e-2)" "unprognostic (2.44e-2)" "unprognostic (7.42e-2)" "unprognostic (6.27e-2)" "unprognostic (1.41e-2)" "unprognostic (1.25e-1)" "unprognostic (3.14e-1)" "unprognostic (2.32e-2)" "unprognostic (1.55e-1)" ZNF177 ENSG00000188629 "Zinc finger protein 177" Q13360 19 9363013-9382617 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 19.1;Bergmann glia: 18.1;Brain excitatory neurons: 12.0;Brain inhibitory neurons: 11.5;Choroid plexus epithelial cells: 11.0;Ependymal cells: 17.3;Microglia: 4.1;Oligodendrocyte progenitor cells: 14.6;Oligodendrocytes: 13.0;Other brain neurons: 13.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" HPA003141 Uncertain NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 21: Testis - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 28: Astrocytes - Homeostasis & neuron support" "HPA003141: " "unprognostic (1.11e-1)" "unprognostic (1.38e-1)" "unprognostic (5.72e-2)" "unprognostic (1.35e-1)" "unprognostic (4.35e-2)" "unprognostic (5.88e-2)" "unprognostic (3.18e-2)" "unprognostic (6.78e-2)" "unprognostic (9.88e-2)" "unprognostic (1.85e-2)" "unprognostic (2.42e-2)" "unprognostic (2.16e-1)" "unprognostic (3.65e-1)" "unprognostic (5.27e-2)" "unprognostic (5.05e-2)" "unprognostic (2.15e-1)" "unprognostic (7.13e-3)" "unprognostic (1.63e-1)" "unprognostic (1.12e-2)" "unprognostic (8.95e-3)" "unprognostic (2.31e-1)" "unprognostic (3.59e-3)" "unprognostic (6.06e-2)" "potential prognostic unfavorable (6.46e-4)" "unprognostic (7.80e-2)" "unprognostic (1.21e-1)" "unprognostic (1.93e-1)" "unprognostic (1.76e-1)" ZNF18 "HDSG1, KOX11, Zfp535, ZKSCAN6, ZNF535, ZSCAN38" ENSG00000154957 "Zinc finger protein 18" P17022 17 11977439-11997475 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 40.0;Late spermatids: 42.4;Neutrophils: 28.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in all" 4 "testis cancer: 34.3" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006144 Uncertain Approved "Nucleoplasm,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 39: Testis - Nuclear processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" 3 "Nucleoplasm, Golgi apparatus" "Plasma membrane, Cytosol" "HPA006144: " "unprognostic (8.63e-2)" "unprognostic (1.10e-1)" "unprognostic (9.47e-2)" "unprognostic (3.00e-2)" "unprognostic (2.27e-1)" "unprognostic (1.17e-1)" "unprognostic (4.19e-2)" "unprognostic (2.16e-1)" "unprognostic (3.29e-3)" "unprognostic (1.16e-2)" "potential prognostic unfavorable (9.86e-6)" "unprognostic (4.43e-2)" "potential prognostic favorable (6.51e-5)" "unprognostic (8.03e-2)" "unprognostic (1.39e-3)" "unprognostic (7.62e-2)" "unprognostic (1.90e-1)" "unprognostic (1.05e-1)" "unprognostic (1.21e-1)" "unprognostic (1.03e-1)" "unprognostic (1.74e-1)" "potential prognostic favorable (3.16e-5)" "unprognostic (7.81e-2)" "unprognostic (3.25e-1)" "unprognostic (7.89e-2)" "unprognostic (9.86e-2)" "unprognostic (2.18e-2)" "unprognostic (1.92e-2)" "unprognostic (7.98e-2)" "potential prognostic unfavorable (7.89e-4)" "unprognostic (1.27e-1)" ZNF180 HHZ168 ENSG00000167384 "Zinc finger protein 180" Q9UJW8 19 44474428-44500524 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028979, HPA028980" Uncertain Approved Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 3 Nucleoplasm "HPA028979: , HPA028980: " "unprognostic (4.44e-2)" "unprognostic (1.15e-1)" "unprognostic (1.24e-2)" "unprognostic (8.62e-2)" "unprognostic (2.75e-2)" "unprognostic (2.65e-1)" "unprognostic (1.52e-1)" "unprognostic (1.04e-1)" "unprognostic (6.56e-3)" "unprognostic (2.54e-1)" "unprognostic (3.97e-3)" "unprognostic (2.48e-2)" "unprognostic (2.70e-3)" "unprognostic (1.36e-2)" "unprognostic (9.89e-2)" "unprognostic (1.80e-1)" "unprognostic (1.32e-1)" "potential prognostic favorable (1.18e-4)" "unprognostic (1.16e-2)" "unprognostic (2.30e-2)" "unprognostic (3.29e-1)" "unprognostic (2.38e-2)" "unprognostic (2.75e-1)" "unprognostic (8.75e-2)" "unprognostic (1.93e-1)" "unprognostic (2.25e-2)" "unprognostic (2.94e-2)" "unprognostic (2.21e-1)" "unprognostic (6.04e-3)" "unprognostic (1.17e-1)" "unprognostic (8.13e-2)" ZNF181 "HHZ181, MGC44316" ENSG00000197841 "Zinc finger protein 181" Q2M3W8 19 34734155-34745378 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA043701, HPA062305" Uncertain Approved Nucleoplasm NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 1 Nucleoplasm "HPA043701: , HPA062305: " "unprognostic (1.16e-3)" "unprognostic (1.27e-1)" "unprognostic (3.22e-1)" "unprognostic (7.65e-3)" "unprognostic (3.24e-1)" "unprognostic (3.46e-1)" "unprognostic (2.93e-1)" "unprognostic (1.58e-1)" "unprognostic (1.14e-2)" "unprognostic (2.12e-2)" "potential prognostic favorable (2.87e-6)" "unprognostic (1.63e-3)" "unprognostic (3.12e-3)" "unprognostic (1.08e-1)" "potential prognostic favorable (7.28e-5)" "unprognostic (6.05e-2)" "unprognostic (7.22e-2)" "unprognostic (2.36e-1)" "unprognostic (9.40e-2)" "unprognostic (2.61e-1)" "unprognostic (1.14e-1)" "unprognostic (2.27e-3)" "unprognostic (1.63e-1)" "unprognostic (4.72e-1)" "unprognostic (2.62e-3)" "unprognostic (4.03e-3)" "unprognostic (1.46e-2)" "unprognostic (1.81e-1)" "unprognostic (1.69e-1)" "unprognostic (2.70e-1)" "unprognostic (3.26e-1)" ZNF182 "HHZ150, KOX14, Zfp182, ZNF21" ENSG00000147118 "Zinc finger protein 182" P17025 X 47974851-48003989 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059574 Uncertain Approved Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 54: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 1 Nucleoplasm "HPA059574: " "unprognostic (9.08e-2)" "unprognostic (8.12e-2)" "unprognostic (2.11e-1)" "unprognostic (2.57e-2)" "unprognostic (2.73e-1)" "unprognostic (1.71e-1)" "unprognostic (7.95e-2)" "unprognostic (1.92e-3)" "unprognostic (2.97e-3)" "unprognostic (2.42e-1)" "unprognostic (8.78e-2)" "unprognostic (1.16e-1)" "unprognostic (2.20e-1)" "unprognostic (1.47e-3)" "unprognostic (6.90e-2)" "unprognostic (4.48e-3)" "unprognostic (8.97e-2)" "unprognostic (2.15e-1)" "unprognostic (3.08e-2)" "unprognostic (1.69e-1)" "unprognostic (4.04e-1)" "unprognostic (1.30e-2)" "unprognostic (4.91e-3)" "unprognostic (1.57e-1)" "unprognostic (6.97e-2)" "unprognostic (2.63e-1)" "unprognostic (2.03e-1)" "unprognostic (2.60e-1)" "unprognostic (6.13e-2)" "unprognostic (5.52e-2)" "unprognostic (9.56e-2)" ZNF184 ENSG00000096654 "Zinc finger protein 184" Q99676 6 27450743-27473118 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 30.0;Late primary spermatocytes: 39.5;Tuft cells: 34.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "HPA003226, HPA064793" Uncertain Supported Nucleoplasm NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 53: Neurons - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 103: Non-specific - Basic cellular processes" 4 Nucleoplasm "HPA003226: , HPA064793: " "unprognostic (1.60e-2)" "unprognostic (4.02e-2)" "unprognostic (4.80e-1)" "unprognostic (1.62e-1)" "unprognostic (1.16e-1)" "unprognostic (4.47e-2)" "unprognostic (4.59e-2)" "unprognostic (8.72e-3)" "unprognostic (8.35e-2)" "unprognostic (5.27e-2)" "validated prognostic favorable (1.99e-7)" "validated prognostic favorable (3.26e-4)" "unprognostic (1.74e-1)" "unprognostic (1.14e-2)" "unprognostic (1.31e-1)" "unprognostic (3.91e-2)" "unprognostic (2.61e-1)" "unprognostic (3.88e-2)" "unprognostic (3.17e-2)" "unprognostic (2.60e-3)" "unprognostic (3.09e-2)" "unprognostic (8.90e-2)" "unprognostic (9.40e-2)" "unprognostic (3.19e-2)" "unprognostic (1.39e-3)" "unprognostic (2.02e-2)" "unprognostic (8.94e-2)" "unprognostic (1.36e-1)" "unprognostic (6.78e-2)" "unprognostic (6.63e-2)" "unprognostic (3.90e-1)" ZNF185 SCELL ENSG00000147394 "Zinc finger protein 185 with LIM domain" O15231 X 152898067-152973481 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 310.5;esophagus: 317.2" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 279.2;Esophageal apical cells: 1653.1;Esophageal suprabasal cells: 528.8;Platelets: 255.8;Somatotrophs: 158.7;Suprabasal keratinocytes: 175.8" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 16.3" "Cancer enhanced" "Detected in all" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 87.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 48.9" "Group enriched" "Detected in many" 5 "granulocytes: 48.9;monocytes: 24.0" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal cortex cells, Lung - Alveolar cells type 1, Skeletal muscle - Fibroblasts, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA000400, HPA016438" Enhanced Supported "Plasma membrane,Actin filaments,Focal adhesion sites,Cytosol" NA NA 64000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 8 "Plasma membrane, Cytosol" "Actin filaments, Focal adhesion sites" "HPA000400: , HPA016438: " "unprognostic (6.23e-2)" "unprognostic (1.45e-1)" "unprognostic (9.35e-2)" "unprognostic (6.76e-2)" "unprognostic (1.33e-1)" "unprognostic (6.70e-3)" "unprognostic (5.00e-2)" "unprognostic (2.39e-2)" "unprognostic (3.57e-1)" "unprognostic (4.39e-2)" "potential prognostic favorable (9.35e-4)" "unprognostic (4.98e-3)" "unprognostic (7.52e-2)" "unprognostic (2.45e-2)" "unprognostic (1.03e-1)" "potential prognostic unfavorable (2.20e-5)" "unprognostic (1.30e-2)" "unprognostic (3.14e-1)" "unprognostic (4.04e-1)" "unprognostic (5.20e-2)" "unprognostic (2.26e-1)" "potential prognostic unfavorable (1.42e-5)" "unprognostic (5.42e-3)" "unprognostic (2.10e-2)" "unprognostic (1.85e-1)" "unprognostic (2.84e-1)" "unprognostic (1.17e-1)" "unprognostic (1.80e-1)" "unprognostic (1.03e-1)" "unprognostic (1.73e-1)" "unprognostic (2.48e-1)" ZNF189 ENSG00000136870 "Zinc finger protein 189" O75820 9 101398851-101410660 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 79.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 105.6;Corticotrophs: 97.3;Epididymal principal cells: 158.3;Oligodendrocytes: 116.8;Pancreatic acinar cells: 119.8;Somatotrophs: 122.4" "Cell type enhanced" "Detected in all" "oligodendrocyte: 178.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034814 Uncertain Approved "Intermediate filaments" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 22: Epididymis - Mixed function" "Cluster 34: Non-specific - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 80: Oligodendrocytes - Myelination" "Intermediate filaments" "HPA034814: " "unprognostic (1.20e-1)" "unprognostic (2.63e-2)" "unprognostic (8.02e-2)" "unprognostic (3.89e-2)" "unprognostic (7.29e-2)" "unprognostic (1.49e-1)" "unprognostic (4.52e-2)" "unprognostic (1.30e-2)" "unprognostic (9.20e-2)" "unprognostic (1.81e-1)" "validated prognostic favorable (2.51e-9)" "validated prognostic favorable (8.24e-6)" "unprognostic (7.41e-2)" "unprognostic (1.80e-2)" "unprognostic (9.71e-2)" "unprognostic (1.24e-1)" "unprognostic (3.36e-1)" "unprognostic (1.88e-2)" "unprognostic (2.14e-2)" "unprognostic (1.92e-1)" "unprognostic (6.32e-2)" "unprognostic (5.09e-2)" "unprognostic (1.88e-1)" "unprognostic (4.45e-2)" "unprognostic (1.99e-2)" "unprognostic (1.01e-1)" "unprognostic (3.14e-2)" "unprognostic (7.20e-2)" "unprognostic (1.16e-1)" "unprognostic (9.18e-2)" "unprognostic (7.72e-2)" ZNF19 "KOX12, MGC51021" ENSG00000157429 "Zinc finger protein 19" P17023 16 71464555-71565089 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cholangiocytes: 64.3;Choroid plexus epithelial cells: 151.6;Ependymal cells: 224.0;Fallopian tube ciliated cells: 74.2;Respiratory ciliated cells: 185.0;Rod photoreceptor cells: 55.8;Somatotrophs: 60.5;Thyrotrophs: 58.5" "Group enriched" "Detected in all" 5 "choroid plexus epithelial cell: 142.5;ependymal cell: 241.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Testis - Early spermatids" HPA063685 Approved Approved Mitochondria NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 7: Liver cancer - Metabolism" "Cluster 34: Ciliated cells - Cilia assembly & function" 24 Mitochondria "HPA063685: " "unprognostic (4.37e-2)" "unprognostic (2.85e-3)" "unprognostic (1.92e-2)" "unprognostic (3.88e-3)" "unprognostic (6.69e-2)" "unprognostic (6.90e-2)" "unprognostic (4.71e-2)" "unprognostic (3.00e-2)" "unprognostic (1.25e-2)" "unprognostic (1.86e-1)" "unprognostic (2.86e-3)" "potential prognostic favorable (6.98e-4)" "unprognostic (3.83e-3)" "unprognostic (8.79e-2)" "unprognostic (2.62e-2)" "unprognostic (1.82e-2)" "unprognostic (1.92e-1)" "unprognostic (1.33e-1)" "unprognostic (1.16e-1)" "unprognostic (3.64e-2)" "unprognostic (1.12e-1)" "potential prognostic favorable (4.94e-4)" "unprognostic (3.82e-2)" "unprognostic (2.35e-1)" "unprognostic (5.53e-3)" "unprognostic (5.13e-3)" "unprognostic (2.85e-1)" "unprognostic (2.11e-1)" "unprognostic (3.41e-1)" "unprognostic (4.35e-1)" "unprognostic (2.56e-1)" ZNF195 ENSG00000005801 "Zinc finger protein 195" O14628 11 3339261-3379222 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA030605 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 64: Non-specific - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 24: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 3 Nucleoplasm Cytosol "HPA030605: " "unprognostic (2.10e-2)" "unprognostic (1.42e-1)" "unprognostic (1.44e-1)" "potential prognostic unfavorable (8.05e-4)" "unprognostic (1.90e-1)" "unprognostic (7.44e-2)" "unprognostic (9.07e-2)" "unprognostic (1.53e-1)" "unprognostic (2.65e-1)" "unprognostic (3.04e-2)" "unprognostic (1.36e-3)" "unprognostic (1.57e-2)" "unprognostic (8.93e-2)" "unprognostic (1.56e-3)" "unprognostic (5.54e-2)" "unprognostic (7.05e-2)" "unprognostic (5.45e-3)" "unprognostic (2.93e-1)" "unprognostic (3.40e-2)" "unprognostic (2.13e-1)" "unprognostic (1.44e-1)" "unprognostic (5.45e-2)" "unprognostic (2.56e-2)" "unprognostic (9.25e-3)" "unprognostic (5.77e-3)" "unprognostic (9.22e-2)" "unprognostic (1.44e-2)" "unprognostic (1.09e-1)" "unprognostic (3.15e-1)" "unprognostic (1.72e-1)" "unprognostic (8.51e-2)" ZNF197 "D3S1363E, P18, ZKSCAN9, ZNF166, ZSCAN41" ENSG00000186448 "Zinc finger protein 197" O14709 3 44584888-44648471 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 55.2;Bergmann glia: 67.1;Brain excitatory neurons: 39.8;Brain inhibitory neurons: 43.2;Choroid plexus epithelial cells: 36.2;Distal convoluted tubule cells: 27.5;Ependymal cells: 47.5;Loop of henle epithelial cells: 33.6;Microglia: 33.6;Oligodendrocyte progenitor cells: 62.3;Oligodendrocytes: 53.3;Other brain neurons: 42.3;Podocytes: 37.9;Proximal tubule cells: 23.6;Renal collecting duct intercalated cells: 27.8;Renal collecting duct principal cells: 25.0;Renal connecting tubule cells: 23.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 4.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054567 Uncertain Approved Nucleoplasm NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 102: Non-specific - Mixed function" 6 Nucleoplasm "HPA054567: " "unprognostic (6.05e-3)" "unprognostic (1.51e-1)" "unprognostic (6.29e-3)" "potential prognostic unfavorable (2.38e-4)" "unprognostic (1.54e-1)" "unprognostic (2.30e-2)" "unprognostic (1.59e-1)" "unprognostic (2.64e-2)" "unprognostic (1.85e-2)" "unprognostic (1.81e-3)" "potential prognostic favorable (7.68e-5)" "unprognostic (6.51e-3)" "unprognostic (2.95e-1)" "unprognostic (3.14e-2)" "unprognostic (2.80e-2)" "unprognostic (1.29e-1)" "potential prognostic unfavorable (9.19e-4)" "unprognostic (3.80e-1)" "unprognostic (3.73e-1)" "unprognostic (8.50e-2)" "unprognostic (1.23e-2)" "unprognostic (2.57e-1)" "unprognostic (6.71e-2)" "potential prognostic unfavorable (7.82e-4)" "unprognostic (1.28e-2)" "unprognostic (1.61e-1)" "unprognostic (1.65e-2)" "unprognostic (9.70e-2)" "unprognostic (4.07e-2)" "unprognostic (4.19e-2)" "unprognostic (5.91e-2)" ZNF2 "A1-5, Zfp661, ZNF661" ENSG00000275111 "Zinc finger protein 2" Q9BSG1 2 95165432-95184317 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 45.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041358 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 61: Non-specific - Transcription" "Cluster 9: Non-specific - Receptor signaling" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 65: Non-specific - Cell growth & division" 7 "Plasma membrane, Cytosol" Nucleoplasm "HPA041358: " "unprognostic (1.29e-2)" "unprognostic (4.41e-2)" "unprognostic (1.30e-1)" "unprognostic (5.35e-2)" "unprognostic (1.11e-1)" "unprognostic (2.68e-2)" "unprognostic (8.11e-2)" "unprognostic (6.07e-2)" "unprognostic (1.35e-2)" "potential prognostic favorable (1.50e-5)" "unprognostic (2.18e-3)" "unprognostic (8.13e-2)" "potential prognostic unfavorable (2.07e-5)" "unprognostic (9.63e-2)" "unprognostic (2.67e-2)" "unprognostic (1.27e-1)" "unprognostic (2.27e-2)" "unprognostic (7.15e-3)" "unprognostic (1.26e-1)" "unprognostic (9.24e-2)" "unprognostic (2.10e-2)" "unprognostic (4.10e-2)" "unprognostic (4.10e-2)" "unprognostic (3.03e-1)" "unprognostic (5.88e-2)" "unprognostic (4.34e-2)" "unprognostic (1.25e-1)" "unprognostic (5.75e-2)" ZNF20 KOX13 ENSG00000132010 "Zinc finger protein 20" P17024 19 12092843-12140355 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 32.2;Early spermatids: 49.8;Epicardial cells: 22.7;Epididymal efferent duct ciliated cells: 26.4;Late primary spermatocytes: 30.2;Late spermatids: 69.0;Respiratory ciliated cells: 31.3" "Cell type enhanced" "Detected in all" "ependymal cell: 25.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "HPA020887, HPA073206" Uncertain Approved "Nucleoplasm,Nuclear membrane,Nuclear bodies" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 43 "Nuclear membrane" "Nucleoplasm, Nuclear bodies" "HPA020887: , HPA073206: " "unprognostic (2.28e-2)" "unprognostic (2.22e-1)" "unprognostic (2.05e-1)" "unprognostic (4.13e-3)" "unprognostic (1.82e-1)" "unprognostic (3.15e-1)" "unprognostic (1.06e-1)" "unprognostic (1.69e-1)" "potential prognostic favorable (5.43e-5)" "potential prognostic unfavorable (3.81e-4)" "unprognostic (3.31e-1)" "unprognostic (2.20e-3)" "unprognostic (6.41e-3)" "unprognostic (1.17e-1)" "unprognostic (2.91e-2)" "unprognostic (6.14e-2)" "unprognostic (6.68e-2)" "unprognostic (1.71e-1)" "unprognostic (1.43e-1)" "unprognostic (8.13e-2)" "unprognostic (2.73e-2)" "unprognostic (4.65e-2)" "unprognostic (1.20e-1)" "unprognostic (8.87e-3)" "unprognostic (5.85e-1)" "unprognostic (7.03e-3)" "unprognostic (1.54e-1)" "unprognostic (9.39e-2)" "unprognostic (8.74e-2)" "unprognostic (1.52e-1)" ZNF200 ENSG00000010539 "Zinc finger protein 200" P98182 16 3222325-3236221 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 16.8" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 38.8;Early primary spermatocytes: 48.3;Early spermatids: 43.1;Late primary spermatocytes: 55.1;Neutrophils: 48.2;Tuft cells: 34.6;Undifferentiated spermatogonia: 29.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "HPA018981, HPA059310" Uncertain Approved Mitochondria No No "Cluster 4: Neutrophils - Degranulation" "Cluster 39: Testis - Nuclear processes" "Cluster 35: Non-specific - DNA binding" "Cluster 54: Non-specific - Transcription" "Cluster 24: Neutrophils - Innate immunity signal integration" 2 Mitochondria "HPA018981: , HPA059310: " "unprognostic (8.46e-2)" "unprognostic (5.26e-2)" "unprognostic (8.62e-2)" "unprognostic (2.45e-1)" "unprognostic (4.84e-2)" "unprognostic (2.16e-3)" "unprognostic (1.62e-1)" "unprognostic (1.37e-1)" "unprognostic (1.26e-1)" "unprognostic (1.11e-1)" "potential prognostic favorable (9.01e-6)" "unprognostic (2.03e-1)" "unprognostic (4.45e-2)" "unprognostic (3.24e-2)" "unprognostic (1.29e-1)" "unprognostic (1.27e-2)" "unprognostic (3.36e-1)" "unprognostic (2.02e-1)" "unprognostic (8.97e-3)" "unprognostic (3.03e-1)" "unprognostic (4.34e-1)" "unprognostic (1.73e-1)" "unprognostic (1.81e-3)" "unprognostic (1.81e-2)" "potential prognostic favorable (7.99e-4)" "unprognostic (2.20e-1)" "unprognostic (4.62e-2)" "unprognostic (1.50e-1)" "unprognostic (2.09e-1)" "unprognostic (1.48e-1)" "unprognostic (4.38e-1)" ZNF202 "ZKSCAN10, ZSCAN42" ENSG00000166261 "Zinc finger protein 202" O95125 11 123723914-123741675 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059229 Approved "Nucleoli rim,Nuclear bodies,Mitotic chromosome" Yes No "Cluster 24: Non-specific - Transcription" "Cluster 39: Testis - Nuclear processes" "Cluster 34: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 17 "Nucleoli rim, Mitotic chromosome" "Nuclear bodies" "HPA059229: " "unprognostic (3.74e-2)" "unprognostic (1.13e-2)" "potential prognostic favorable (5.00e-4)" "unprognostic (1.07e-1)" "unprognostic (7.21e-2)" "unprognostic (3.05e-1)" "unprognostic (6.53e-2)" "potential prognostic favorable (6.09e-4)" "unprognostic (1.88e-1)" "unprognostic (2.79e-3)" "unprognostic (1.12e-1)" "potential prognostic favorable (7.60e-4)" "unprognostic (7.16e-2)" "potential prognostic unfavorable (4.05e-6)" "unprognostic (9.25e-2)" "unprognostic (1.86e-2)" "unprognostic (1.37e-2)" "unprognostic (1.14e-1)" "unprognostic (4.41e-3)" "unprognostic (1.29e-1)" "unprognostic (1.09e-1)" "unprognostic (9.06e-2)" "potential prognostic unfavorable (2.75e-4)" "unprognostic (2.88e-2)" "potential prognostic favorable (4.38e-4)" "unprognostic (1.73e-1)" "potential prognostic unfavorable (9.32e-4)" "unprognostic (9.03e-2)" "unprognostic (1.40e-1)" "unprognostic (2.53e-1)" "unprognostic (2.29e-2)" ZNF205 "Zfp13, ZNF210" ENSG00000122386 "Zinc finger protein 205" O95201 16 3112560-3120517 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Tuft cells: 46.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001791 Uncertain Approved Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 54: Non-specific - Transcription" "Cluster 95: Tuft cells - Chemosensory signaling" 8 Nucleoplasm "HPA001791: " "unprognostic (1.06e-1)" "unprognostic (1.57e-1)" "unprognostic (2.24e-2)" "unprognostic (1.97e-2)" "unprognostic (2.29e-1)" "unprognostic (5.38e-2)" "unprognostic (3.85e-1)" "unprognostic (4.37e-3)" "unprognostic (1.71e-2)" "unprognostic (1.20e-1)" "unprognostic (5.04e-3)" "unprognostic (1.43e-1)" "unprognostic (1.38e-2)" "potential prognostic unfavorable (9.71e-7)" "unprognostic (2.78e-1)" "unprognostic (1.40e-1)" "unprognostic (7.27e-2)" "unprognostic (2.57e-1)" "unprognostic (2.83e-2)" "unprognostic (2.75e-2)" "unprognostic (4.13e-1)" "unprognostic (3.90e-2)" "unprognostic (1.07e-1)" "unprognostic (8.25e-3)" "unprognostic (7.51e-2)" "unprognostic (9.73e-2)" "unprognostic (1.22e-1)" "unprognostic (4.58e-2)" "unprognostic (3.78e-1)" "unprognostic (2.06e-1)" "unprognostic (2.42e-2)" ZNF207 BuGZ ENSG00000010244 "Zinc finger protein 207" O43670 17 32350132-32381885 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017013, HPA063908" Enhanced Enhanced Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 10 Nucleoplasm "HPA017013: , HPA063908: " "unprognostic (3.57e-1)" "unprognostic (7.34e-2)" "unprognostic (1.49e-1)" "unprognostic (4.78e-2)" "potential prognostic favorable (8.69e-4)" "unprognostic (9.45e-2)" "unprognostic (2.00e-1)" "unprognostic (1.72e-2)" "unprognostic (1.81e-1)" "potential prognostic unfavorable (9.16e-5)" "potential prognostic favorable (3.25e-5)" "unprognostic (6.19e-2)" "unprognostic (4.76e-2)" "validated prognostic unfavorable (1.93e-5)" "validated prognostic unfavorable (1.90e-4)" "potential prognostic unfavorable (3.46e-4)" "unprognostic (2.34e-2)" "unprognostic (3.90e-1)" "unprognostic (1.73e-1)" "unprognostic (6.67e-2)" "unprognostic (8.10e-2)" "unprognostic (4.29e-3)" "potential prognostic unfavorable (9.59e-4)" "unprognostic (1.92e-1)" "unprognostic (8.05e-2)" "unprognostic (1.82e-2)" "unprognostic (7.13e-2)" "unprognostic (1.06e-1)" "unprognostic (3.35e-1)" "unprognostic (2.94e-1)" "unprognostic (1.30e-1)" ZNF208 "PMIDP, ZNF95" ENSG00000160321 "Zinc finger protein 208" O43345 19 21932958-22010949 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 180.8;Corticotrophs: 71.1;Distal convoluted tubule cells: 71.2;Pituicytes/FSCs: 108.1;Podocytes: 81.6;Renal collecting duct intercalated cells: 103.3;Renal collecting duct principal cells: 90.4;Renal connecting tubule cells: 167.5;Sertoli cells: 153.1" "Cell type enhanced" "Detected in many" "hippocampal CA4: 98.2" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 28.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" HPA077100 Uncertain "Golgi apparatus,Cytosol" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 35: Non-specific - Mixed function" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 4: Non-specific - Transcription" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" "Golgi apparatus" Cytosol "HPA077100: " "unprognostic (4.81e-2)" "unprognostic (1.02e-1)" "unprognostic (2.43e-1)" "unprognostic (1.47e-1)" "potential prognostic unfavorable (4.18e-4)" "unprognostic (2.16e-1)" "unprognostic (2.46e-1)" "unprognostic (7.24e-2)" "unprognostic (3.33e-2)" "unprognostic (1.66e-2)" "unprognostic (7.00e-2)" "unprognostic (1.66e-2)" "unprognostic (3.36e-1)" "unprognostic (3.16e-2)" "unprognostic (2.77e-2)" "unprognostic (2.96e-1)" "unprognostic (2.86e-1)" "unprognostic (4.12e-1)" "unprognostic (1.07e-1)" "unprognostic (1.45e-3)" "unprognostic (1.86e-2)" "unprognostic (2.40e-2)" "unprognostic (2.60e-1)" "unprognostic (5.29e-1)" "unprognostic (8.17e-3)" "unprognostic (7.37e-2)" "unprognostic (2.74e-1)" "unprognostic (5.38e-1)" "unprognostic (1.12e-1)" "unprognostic (5.80e-2)" ZNF211 "CH2H2-25, ZNF-25" ENSG00000121417 "Zinc finger protein 211" Q13398 19 57630395-57644041 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bergmann glia: 29.6;Syncytiotrophoblasts: 31.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA011340, HPA049967" Approved Approved "Mitochondria,Rods & Rings" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 4: Non-specific - Transcription" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 2 Mitochondria "Rods & Rings" "HPA011340: , HPA049967: " "unprognostic (3.99e-2)" "unprognostic (9.75e-2)" "unprognostic (1.23e-1)" "unprognostic (1.51e-2)" "unprognostic (5.25e-2)" "unprognostic (6.41e-2)" "unprognostic (1.97e-1)" "unprognostic (2.32e-1)" "unprognostic (2.47e-1)" "unprognostic (9.84e-2)" "unprognostic (7.83e-2)" "unprognostic (1.14e-3)" "unprognostic (3.47e-3)" "unprognostic (1.15e-1)" "unprognostic (1.21e-1)" "unprognostic (1.43e-2)" "unprognostic (3.86e-1)" "unprognostic (3.31e-1)" "unprognostic (1.52e-1)" "unprognostic (3.91e-1)" "unprognostic (1.81e-1)" "potential prognostic favorable (5.39e-4)" "unprognostic (3.19e-1)" "unprognostic (2.68e-2)" "unprognostic (5.94e-2)" "unprognostic (3.47e-1)" "unprognostic (1.92e-2)" "unprognostic (2.11e-1)" "unprognostic (2.64e-1)" "unprognostic (3.28e-2)" "unprognostic (1.55e-1)" ZNF212 C2H2-150 ENSG00000170260 "Zinc finger protein 212" Q9UDV6 7 149239651-149255606 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 110.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049807, HPA054178" Uncertain Supported Nucleoplasm NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 25: Non-specific - Transcription" "Cluster 39: Non-specific - Transcription" "Cluster 51: Secretory epithelial cells - Mixed function" 21 Nucleoplasm "HPA049807: , HPA054178: " "unprognostic (1.47e-1)" "unprognostic (1.64e-2)" "unprognostic (3.09e-1)" "unprognostic (2.76e-1)" "potential prognostic unfavorable (8.20e-4)" "unprognostic (3.40e-2)" "unprognostic (9.12e-2)" "unprognostic (1.91e-3)" "unprognostic (1.88e-2)" "unprognostic (4.99e-3)" "unprognostic (5.96e-2)" "unprognostic (1.54e-1)" "unprognostic (7.33e-2)" "unprognostic (3.41e-3)" "unprognostic (2.75e-1)" "unprognostic (7.51e-2)" "unprognostic (1.45e-2)" "unprognostic (2.70e-2)" "unprognostic (5.44e-2)" "unprognostic (1.76e-1)" "unprognostic (3.69e-1)" "unprognostic (4.06e-2)" "unprognostic (4.07e-2)" "unprognostic (1.87e-1)" "unprognostic (9.02e-3)" "unprognostic (4.86e-2)" "unprognostic (9.81e-3)" "unprognostic (6.09e-2)" "unprognostic (1.78e-1)" "unprognostic (4.65e-2)" "unprognostic (3.51e-1)" ZNF213 "CR53, ZKSCAN21, ZSCAN53" ENSG00000085644 "Zinc finger protein 213" O14771 16 3129777-3142804 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 83.7;Late spermatids: 110.0;Myonuclei: 177.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035000, HPA056750" Uncertain Approved "Nucleoplasm,Nuclear membrane,Vesicles,Cytosol" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 67: Testis - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 54: Non-specific - Transcription" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 18 "Nucleoplasm, Nuclear membrane" "Vesicles, Cytosol" "HPA035000: , HPA056750: " "unprognostic (1.66e-2)" "unprognostic (5.43e-3)" "unprognostic (1.65e-1)" "unprognostic (3.79e-2)" "unprognostic (2.97e-1)" "unprognostic (1.76e-1)" "unprognostic (5.43e-1)" "unprognostic (1.17e-2)" "unprognostic (1.89e-2)" "unprognostic (3.52e-1)" "unprognostic (2.22e-1)" "unprognostic (2.24e-1)" "unprognostic (1.03e-1)" "unprognostic (1.89e-3)" "unprognostic (4.11e-2)" "unprognostic (2.28e-2)" "unprognostic (2.10e-1)" "unprognostic (2.66e-3)" "unprognostic (2.35e-2)" "unprognostic (2.77e-1)" "unprognostic (1.82e-1)" "unprognostic (1.54e-1)" "unprognostic (3.61e-1)" "unprognostic (2.83e-1)" "unprognostic (3.19e-2)" "unprognostic (1.83e-1)" "unprognostic (4.61e-1)" "unprognostic (4.08e-2)" "unprognostic (3.12e-2)" "unprognostic (3.39e-1)" "unprognostic (4.30e-2)" ZNF214 ENSG00000149050 "Zinc finger protein 214" Q9UL59 11 6997085-7020346 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ependymal cells: 47.3;Epididymal efferent duct ciliated cells: 22.2;Fallopian tube ciliated cells: 34.0;Late primary spermatocytes: 27.6;Respiratory ciliated cells: 53.9" "Cell type enhanced" "Detected in many" "ependymal cell: 54.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells, Testis - Early spermatids" HPA055391 Uncertain Approved Nucleoplasm,Midbody Yes NA "Cluster 65: Brain - Transcription" "Cluster 17: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" Nucleoplasm Midbody "HPA055391: " "unprognostic (3.18e-1)" "unprognostic (1.88e-1)" "unprognostic (2.78e-3)" "unprognostic (6.18e-2)" "unprognostic (7.80e-2)" "unprognostic (6.77e-3)" "potential prognostic favorable (9.59e-6)" "unprognostic (3.83e-3)" "unprognostic (1.68e-2)" "unprognostic (3.64e-2)" "unprognostic (4.37e-2)" "unprognostic (1.02e-1)" "unprognostic (2.46e-1)" "unprognostic (7.96e-2)" "unprognostic (6.72e-2)" "unprognostic (1.34e-1)" "unprognostic (3.26e-2)" "unprognostic (2.64e-2)" "unprognostic (2.03e-1)" "unprognostic (1.91e-2)" ZNF215 "ZKSCAN11, ZSCAN43" ENSG00000149054 "Zinc finger protein 215" Q9UL58 11 6926404-7001004 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 3.9" "Cell type enriched" "Detected in many" 5 "Plasma cells: 177.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Breast - Plasma cells, Minor Salivary Gland - Plasma cells" "Low region specificity" "Detected in many" "HPA047243, HPA051010" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 1: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 44: Plasma cells - Antibody production & secretion" "Nucleoplasm, Vesicles" "HPA047243: , HPA051010: " "unprognostic (2.52e-2)" "unprognostic (2.82e-1)" "unprognostic (1.85e-1)" "potential prognostic favorable (4.87e-4)" "unprognostic (2.05e-1)" "unprognostic (4.20e-2)" "unprognostic (1.21e-1)" "unprognostic (4.54e-2)" "unprognostic (3.97e-2)" "unprognostic (1.43e-2)" "unprognostic (1.39e-1)" "unprognostic (8.14e-2)" "unprognostic (2.32e-1)" "unprognostic (2.84e-3)" "unprognostic (5.43e-3)" "unprognostic (2.96e-2)" "unprognostic (4.31e-2)" "unprognostic (8.04e-2)" "unprognostic (3.86e-1)" "unprognostic (3.69e-2)" ZNF217 ZABC1 ENSG00000171940 "Zinc finger protein 217" O75362 20 53567071-53609907 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 249.5;Epididymal clear cells: 206.2;Neutrophils: 268.6;Ocular epithelial cells: 363.5;Urothelial cells: 200.2" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 85.3;leukocyte: 95.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Spermatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051857 Approved Enhanced "Nuclear speckles,Mitochondria" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 39: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 100: Stratified epithelial cells - Barrier functions" 22 "Nuclear speckles" Mitochondria "HPA051857: " "unprognostic (2.72e-2)" "unprognostic (2.81e-2)" "unprognostic (1.49e-1)" "unprognostic (4.69e-2)" "unprognostic (2.07e-1)" "unprognostic (5.17e-1)" "unprognostic (1.35e-1)" "unprognostic (1.78e-3)" "unprognostic (8.72e-2)" "unprognostic (1.30e-1)" "potential prognostic favorable (4.68e-4)" "unprognostic (2.12e-1)" "unprognostic (5.99e-2)" "unprognostic (1.46e-3)" "unprognostic (4.51e-2)" "unprognostic (5.03e-2)" "unprognostic (1.98e-2)" "unprognostic (1.97e-1)" "unprognostic (2.52e-2)" "unprognostic (2.28e-2)" "unprognostic (1.63e-3)" "unprognostic (4.32e-3)" "unprognostic (2.66e-3)" "unprognostic (1.91e-2)" "unprognostic (6.44e-3)" "unprognostic (6.08e-2)" "unprognostic (2.09e-1)" "unprognostic (4.15e-1)" "unprognostic (3.60e-1)" "unprognostic (2.72e-1)" "unprognostic (6.90e-2)" ZNF219 ENSG00000165804 "Zinc finger protein 219" Q9P2Y4 14 21090077-21104722 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 68.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030761, HPA056168" Approved Supported Nucleoplasm NA NA "Cluster 64: Non-specific - Transcription" "Cluster 44: Non-specific - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 26 Nucleoplasm "HPA030761: , HPA056168: " "unprognostic (2.93e-2)" "unprognostic (4.05e-3)" "unprognostic (2.35e-1)" "potential prognostic unfavorable (1.69e-5)" "unprognostic (4.82e-2)" "unprognostic (2.71e-2)" "unprognostic (3.24e-2)" "unprognostic (1.28e-3)" "unprognostic (9.86e-2)" "unprognostic (8.73e-2)" "unprognostic (8.77e-3)" "unprognostic (1.10e-1)" "unprognostic (8.81e-3)" "unprognostic (8.17e-2)" "unprognostic (2.14e-2)" "unprognostic (6.22e-2)" "unprognostic (7.76e-2)" "unprognostic (2.86e-1)" "unprognostic (2.67e-3)" "unprognostic (2.38e-1)" "unprognostic (5.38e-2)" "unprognostic (9.33e-2)" "unprognostic (3.40e-1)" "unprognostic (8.46e-2)" "unprognostic (3.05e-2)" "unprognostic (3.04e-2)" "unprognostic (4.94e-2)" "unprognostic (1.34e-1)" "unprognostic (1.68e-1)" "unprognostic (1.56e-2)" "potential prognostic favorable (6.68e-5)" ZNF22 "HKR-T1, KOX15, Zfp422, ZNF422" ENSG00000165512 "Zinc finger protein 22" P17026 10 45000923-45005326 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016736, HPA054893" Approved Enhanced Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 55: Non-specific - Transcription" "Cluster 6: Leukemia - Signal transduction" "Cluster 17: Non-specific - RNA processing" 22 Nucleoplasm "HPA016736: , HPA054893: " "unprognostic (1.64e-1)" "unprognostic (1.46e-1)" "unprognostic (4.17e-1)" "potential prognostic unfavorable (8.30e-4)" "unprognostic (1.30e-1)" "unprognostic (3.68e-2)" "unprognostic (3.91e-3)" "potential prognostic favorable (2.01e-5)" "unprognostic (1.05e-1)" "unprognostic (9.35e-2)" "unprognostic (3.14e-3)" "unprognostic (4.45e-2)" "unprognostic (2.32e-1)" "unprognostic (2.26e-2)" "unprognostic (1.67e-1)" "unprognostic (1.35e-1)" "unprognostic (1.60e-1)" "unprognostic (8.66e-2)" "unprognostic (3.90e-2)" "unprognostic (2.20e-1)" "unprognostic (2.26e-1)" "unprognostic (7.85e-2)" "unprognostic (1.03e-1)" "unprognostic (5.20e-2)" "unprognostic (6.68e-2)" "unprognostic (8.58e-2)" "unprognostic (2.62e-3)" "potential prognostic unfavorable (1.63e-4)" "unprognostic (1.84e-1)" "unprognostic (4.84e-2)" "unprognostic (2.63e-1)" ZNF221 ENSG00000159905 "Zinc finger protein 221" Q9UK13 19 43951223-43967709 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 10.7;Choroid plexus epithelial cells: 8.9;Fibro-adipogenic progenitors: 6.7;Lactotrophs: 7.3;Thyrotrophs: 6.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" HPA059435 Uncertain Approved "Nuclear bodies" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 3 "Nuclear bodies" "HPA059435: " "unprognostic (1.49e-1)" "unprognostic (2.52e-1)" "unprognostic (1.24e-1)" "unprognostic (3.44e-2)" "unprognostic (3.13e-1)" "potential prognostic favorable (1.64e-4)" "unprognostic (2.65e-1)" "unprognostic (2.64e-1)" "unprognostic (2.52e-2)" "unprognostic (1.47e-2)" "unprognostic (6.29e-3)" "unprognostic (1.90e-1)" "unprognostic (2.15e-1)" "unprognostic (2.09e-2)" ZNF222 ENSG00000159885 "Zinc finger protein 222" Q9UK12 19 44025342-44033110 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 3.0;Bergmann glia: 3.6;Brain excitatory neurons: 4.3;Brain inhibitory neurons: 4.5;Choroid plexus epithelial cells: 3.1;Early spermatids: 2.4;Ependymal cells: 1.3;Late primary spermatocytes: 2.2;Microglia: 1.7;Oligodendrocyte progenitor cells: 4.7;Oligodendrocytes: 2.9;Other brain neurons: 6.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" HPA004086 Approved Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 109: Neurons - Neuronal signaling" Nucleoplasm "Nuclear bodies" "HPA004086: " "potential prognostic favorable (1.64e-5)" "unprognostic (3.93e-2)" "unprognostic (4.07e-1)" "unprognostic (1.21e-1)" "unprognostic (9.82e-2)" "unprognostic (3.56e-1)" "unprognostic (1.58e-1)" "unprognostic (1.65e-1)" "unprognostic (1.63e-1)" "unprognostic (6.86e-2)" "potential prognostic favorable (1.16e-5)" "unprognostic (7.08e-3)" "unprognostic (1.16e-1)" "potential prognostic unfavorable (5.18e-4)" "unprognostic (3.75e-1)" "unprognostic (4.96e-3)" "unprognostic (1.98e-1)" "unprognostic (3.10e-2)" "unprognostic (1.07e-1)" "unprognostic (2.70e-1)" "unprognostic (2.71e-1)" "potential prognostic favorable (1.35e-5)" "unprognostic (1.48e-1)" "unprognostic (4.59e-2)" "unprognostic (5.88e-3)" "unprognostic (7.22e-2)" "unprognostic (5.72e-3)" "unprognostic (7.85e-2)" "unprognostic (4.47e-1)" "unprognostic (1.93e-1)" "unprognostic (3.02e-1)" ZNF223 ENSG00000178386 "Zinc finger protein 223" Q9UK11 19 44051367-44067999 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 9 "Astrocytes: 5.2;Bergmann glia: 8.1;Brain excitatory neurons: 10.1;Brain inhibitory neurons: 9.5;Choroid plexus epithelial cells: 6.5;Ependymal cells: 4.5;Microglia: 6.9;Oligodendrocyte progenitor cells: 8.1;Oligodendrocytes: 6.6;Other brain neurons: 11.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "HPA067823, HPA079175" Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 98: Neurons - Neurotransmission & signaling" 6 Nucleoplasm Mitochondria "HPA067823: , HPA079175: " "unprognostic (3.18e-3)" "unprognostic (6.39e-2)" "unprognostic (2.03e-1)" "unprognostic (2.06e-2)" "unprognostic (2.61e-1)" "unprognostic (1.74e-1)" "unprognostic (1.27e-1)" "unprognostic (4.49e-1)" "unprognostic (4.72e-1)" "unprognostic (1.72e-2)" "potential prognostic favorable (1.90e-4)" "unprognostic (1.16e-3)" "potential prognostic favorable (2.10e-4)" "unprognostic (1.19e-1)" "unprognostic (1.12e-2)" "unprognostic (2.13e-1)" "unprognostic (2.21e-1)" "unprognostic (8.38e-2)" "unprognostic (2.15e-1)" "unprognostic (1.09e-1)" "unprognostic (4.45e-1)" "unprognostic (3.65e-2)" "unprognostic (2.32e-1)" "unprognostic (4.65e-2)" "unprognostic (4.05e-2)" "unprognostic (1.71e-1)" "unprognostic (1.65e-3)" "unprognostic (2.38e-1)" "unprognostic (2.54e-2)" "unprognostic (1.24e-1)" "unprognostic (1.60e-2)" ZNF224 "BMZF-2, KOX22, ZNF255, ZNF27" ENSG00000267680 "Zinc finger protein 224" Q9NZL3 19 44094361-44109886 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA054045 Approved Supported "Nucleoplasm,Nuclear membrane" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 49: Non-specific - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 7 "Nuclear membrane" Nucleoplasm "HPA054045: " "potential prognostic favorable (2.47e-4)" "unprognostic (3.11e-2)" "unprognostic (2.28e-2)" "unprognostic (1.00e-1)" "unprognostic (7.02e-2)" "unprognostic (3.79e-1)" "unprognostic (1.86e-1)" "unprognostic (8.70e-2)" "potential prognostic favorable (5.96e-4)" "unprognostic (2.79e-1)" "unprognostic (1.88e-1)" "unprognostic (2.27e-3)" "unprognostic (7.49e-3)" "unprognostic (2.34e-1)" "unprognostic (1.48e-3)" "unprognostic (2.01e-1)" "unprognostic (7.24e-2)" "unprognostic (1.26e-1)" "unprognostic (1.27e-2)" "unprognostic (2.33e-1)" "unprognostic (4.07e-1)" "unprognostic (8.07e-3)" "unprognostic (1.96e-2)" "unprognostic (9.97e-2)" "unprognostic (2.48e-3)" "unprognostic (6.68e-2)" "unprognostic (1.59e-2)" "unprognostic (1.21e-1)" "unprognostic (2.51e-1)" "unprognostic (9.64e-2)" "unprognostic (2.00e-1)" ZNF225 ENSG00000256294 "Zinc finger protein 225" Q9UK10 19 44112181-44134822 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 39.4;Late primary spermatocytes: 12.8;Retinal pigment epithelial cells: 12.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" HPA073778 Approved Nucleoplasm NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 1 Nucleoplasm "HPA073778: " "unprognostic (6.03e-2)" "unprognostic (6.80e-2)" "unprognostic (1.29e-1)" "unprognostic (4.34e-2)" "unprognostic (2.36e-1)" "unprognostic (1.36e-1)" "unprognostic (1.44e-1)" "unprognostic (1.11e-1)" "unprognostic (3.91e-2)" "unprognostic (3.18e-2)" "potential prognostic favorable (1.38e-4)" "unprognostic (5.88e-3)" "unprognostic (9.01e-2)" "unprognostic (1.83e-1)" "unprognostic (1.91e-2)" "unprognostic (9.07e-2)" "unprognostic (3.72e-1)" "unprognostic (5.02e-2)" "unprognostic (8.22e-3)" "unprognostic (1.74e-2)" "unprognostic (1.32e-1)" "unprognostic (7.32e-2)" "unprognostic (4.54e-2)" "unprognostic (1.01e-1)" "unprognostic (2.95e-3)" "unprognostic (7.51e-2)" "unprognostic (8.98e-3)" "unprognostic (3.38e-1)" "unprognostic (1.85e-1)" "unprognostic (6.87e-2)" "unprognostic (1.72e-1)" ZNF226 ENSG00000167380 "Zinc finger protein 226" Q9NYT6 19 44165073-44178381 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006145, CAB034353, HPA069192" Uncertain Approved "Nuclear bodies" No No "Cluster 3: Non-specific - Nuclear processes" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 55: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 1 "Nuclear bodies" "CAB034353: , HPA006145: , HPA069192: " "potential prognostic favorable (5.57e-4)" "unprognostic (1.88e-1)" "unprognostic (2.15e-2)" "unprognostic (1.02e-1)" "unprognostic (1.17e-1)" "unprognostic (7.21e-2)" "unprognostic (2.33e-1)" "unprognostic (3.99e-1)" "unprognostic (8.58e-2)" "unprognostic (1.62e-2)" "unprognostic (3.53e-3)" "unprognostic (2.80e-2)" "potential prognostic favorable (1.86e-4)" "unprognostic (1.62e-1)" "unprognostic (1.60e-2)" "unprognostic (3.15e-3)" "unprognostic (1.27e-1)" "unprognostic (7.09e-2)" "unprognostic (2.17e-2)" "unprognostic (3.07e-1)" "unprognostic (2.27e-1)" "unprognostic (1.05e-2)" "unprognostic (8.40e-2)" "unprognostic (1.80e-1)" "unprognostic (2.90e-1)" "unprognostic (5.60e-2)" "unprognostic (1.41e-3)" "unprognostic (7.74e-2)" "unprognostic (7.03e-3)" "unprognostic (1.89e-1)" "unprognostic (1.47e-1)" ZNF227 ENSG00000131115 "Zinc finger protein 227" Q86WZ6 19 44207547-44237268 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 62.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030573 Uncertain Approved "Plasma membrane" NA NA "Cluster 32: Basophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 5 "Plasma membrane" "HPA030573: " "unprognostic (1.85e-2)" "unprognostic (1.32e-1)" "unprognostic (5.08e-1)" "unprognostic (5.09e-2)" "unprognostic (6.85e-2)" "unprognostic (3.63e-2)" "unprognostic (6.51e-2)" "unprognostic (3.96e-1)" "unprognostic (8.89e-2)" "unprognostic (2.60e-1)" "potential prognostic favorable (2.22e-4)" "unprognostic (2.08e-3)" "unprognostic (2.21e-1)" "unprognostic (7.23e-3)" "unprognostic (9.51e-2)" "unprognostic (1.38e-2)" "unprognostic (1.59e-1)" "unprognostic (1.92e-2)" "unprognostic (6.14e-2)" "unprognostic (4.24e-1)" "unprognostic (6.42e-2)" "unprognostic (1.23e-1)" "unprognostic (2.64e-1)" "unprognostic (1.04e-1)" "unprognostic (2.21e-2)" "unprognostic (2.71e-1)" "unprognostic (9.66e-3)" "unprognostic (1.27e-1)" "unprognostic (4.07e-2)" "unprognostic (2.11e-2)" "unprognostic (2.45e-1)" ZNF229 ENSG00000278318 "Zinc finger protein 229" Q9UJW7 19 44417519-44448578 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 11.3;Bergmann glia: 14.9;Brain excitatory neurons: 7.2;Brain inhibitory neurons: 11.4;Choroid plexus epithelial cells: 19.5;Distal convoluted tubule cells: 14.1;Ependymal cells: 8.7;Loop of henle epithelial cells: 8.8;Oligodendrocyte progenitor cells: 9.9;Other brain neurons: 12.2;Podocytes: 16.5;Proximal tubule cells: 6.9;Renal collecting duct intercalated cells: 10.5;Renal collecting duct principal cells: 7.8;Renal connecting tubule cells: 12.9" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 5.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 1.5" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Spleen - Endothelial cells, Thyroid gland - Thyroid glandular cells" HPA001494 Uncertain Uncertain "Vesicles,Plasma membrane" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 21: Non-specific - Metabolism" "Cluster 4: Non-specific - Transcription" "Cluster 102: Non-specific - Mixed function" 1 Vesicles "Plasma membrane" "HPA001494: " "unprognostic (7.35e-3)" "unprognostic (3.90e-1)" "unprognostic (1.28e-1)" "unprognostic (3.37e-1)" "unprognostic (3.29e-2)" "unprognostic (2.63e-3)" "unprognostic (5.68e-3)" "unprognostic (1.82e-2)" "unprognostic (1.39e-2)" "unprognostic (9.48e-2)" "unprognostic (3.31e-2)" "unprognostic (6.74e-2)" "unprognostic (3.85e-3)" "unprognostic (9.99e-3)" "unprognostic (8.44e-2)" "unprognostic (2.33e-3)" ZNF23 "KOX16, Zfp612, ZNF359, ZNF612" ENSG00000167377 "Zinc finger protein 23" P17027 16 71447597-71463095 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 9 "Astrocytes: 18.3;Bergmann glia: 26.0;Brain excitatory neurons: 13.7;Brain inhibitory neurons: 13.1;Choroid plexus epithelial cells: 25.9;Ependymal cells: 43.0;Microglia: 12.9;Oligodendrocyte progenitor cells: 14.6;Oligodendrocytes: 16.3;Other brain neurons: 14.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023534 Uncertain Approved Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 14: Neurons - Synaptic function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 34: Ciliated cells - Cilia assembly & function" 14 Cytosol "HPA023534: " "unprognostic (1.50e-2)" "unprognostic (5.18e-2)" "unprognostic (1.36e-1)" "unprognostic (2.02e-1)" "unprognostic (1.51e-2)" "unprognostic (1.38e-2)" "unprognostic (3.50e-1)" "unprognostic (1.19e-2)" "unprognostic (1.79e-1)" "unprognostic (5.36e-2)" "unprognostic (2.05e-2)" "unprognostic (2.81e-1)" "unprognostic (1.34e-2)" "unprognostic (8.69e-2)" "unprognostic (1.93e-2)" "unprognostic (9.02e-2)" "unprognostic (8.31e-2)" "unprognostic (8.63e-2)" "unprognostic (1.65e-1)" "unprognostic (3.89e-1)" "unprognostic (4.45e-1)" "unprognostic (1.24e-1)" "unprognostic (3.86e-3)" "unprognostic (1.88e-2)" "unprognostic (9.25e-2)" "unprognostic (3.53e-3)" "unprognostic (1.22e-1)" "unprognostic (3.34e-3)" "unprognostic (2.08e-1)" "potential prognostic unfavorable (2.55e-4)" "unprognostic (7.91e-2)" ZNF230 FDZF2 ENSG00000159882 "Zinc finger protein 230" Q9UIE0 19 44002957-44013924 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Neutrophil progenitors: 18.6;Neutrophils: 54.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA006172 Approved Mitochondria No No "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 61: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 24: Neutrophils - Innate immunity signal integration" 6 Mitochondria "HPA006172: " "unprognostic (4.75e-2)" "unprognostic (2.44e-2)" "unprognostic (9.30e-3)" "unprognostic (2.00e-3)" "unprognostic (2.30e-1)" "unprognostic (1.24e-1)" "unprognostic (1.83e-1)" "unprognostic (5.03e-3)" "unprognostic (2.82e-2)" "unprognostic (9.85e-2)" "potential prognostic favorable (5.98e-4)" "unprognostic (6.71e-3)" "unprognostic (4.00e-2)" "unprognostic (9.39e-2)" "unprognostic (2.13e-1)" "unprognostic (6.32e-2)" "unprognostic (3.25e-2)" "unprognostic (1.47e-1)" "unprognostic (3.17e-1)" "unprognostic (4.24e-2)" "unprognostic (5.87e-3)" "unprognostic (1.56e-1)" "unprognostic (4.21e-2)" "unprognostic (2.69e-2)" "unprognostic (2.51e-2)" "unprognostic (2.71e-2)" "unprognostic (2.54e-1)" "unprognostic (3.25e-1)" "unprognostic (9.29e-2)" "potential prognostic unfavorable (4.02e-4)" ZNF232 ZSCAN11 ENSG00000167840 "Zinc finger protein 232" Q9UNY5 17 5105269-5123162 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 29.0;Early primary spermatocytes: 39.2;Respiratory ciliated cells: 29.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027309, HPA028611" Uncertain Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 42: Non-specific - Unknown function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 30 Nucleoplasm "Vesicles, Cytosol" "HPA027309: , HPA028611: " "unprognostic (1.36e-1)" "unprognostic (8.67e-2)" "unprognostic (2.47e-1)" "potential prognostic favorable (5.82e-5)" "unprognostic (2.76e-1)" "unprognostic (2.80e-2)" "unprognostic (4.07e-2)" "unprognostic (1.89e-2)" "unprognostic (3.82e-3)" "unprognostic (2.66e-1)" "unprognostic (1.60e-1)" "unprognostic (1.63e-1)" "unprognostic (3.94e-3)" "unprognostic (1.02e-1)" "unprognostic (1.65e-1)" "unprognostic (1.58e-1)" "unprognostic (7.38e-3)" "unprognostic (1.62e-1)" "unprognostic (6.26e-3)" "unprognostic (1.02e-1)" "potential prognostic favorable (1.55e-4)" "unprognostic (1.05e-1)" "unprognostic (1.15e-1)" "unprognostic (1.52e-2)" "unprognostic (6.12e-2)" "unprognostic (5.43e-2)" "unprognostic (1.85e-1)" "unprognostic (2.89e-1)" "unprognostic (1.93e-1)" "unprognostic (6.20e-2)" ZNF233 FLJ38032 ENSG00000159915 "Zinc finger protein 233" A6NK53 19 44259880-44275317 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "testis: 13.6" "Group enriched" "Detected in many" 4 "Cardiomyocytes: 57.1;Early spermatids: 26.5;Epicardial cells: 45.5;Late primary spermatocytes: 97.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Prostate - Prostate glandular cells, Testis - Early spermatids" HPA020975 Uncertain Approved Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 40: Non-specific - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 4: Non-specific - Transcription" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" Nucleoplasm "HPA020975: " "unprognostic (1.21e-2)" "unprognostic (1.10e-1)" "unprognostic (3.88e-1)" "unprognostic (2.38e-1)" "unprognostic (2.45e-1)" "unprognostic (9.01e-2)" "unprognostic (1.21e-2)" "unprognostic (1.47e-1)" "unprognostic (1.48e-2)" "unprognostic (2.55e-3)" "unprognostic (1.44e-1)" "unprognostic (1.19e-1)" "unprognostic (1.84e-1)" "unprognostic (2.38e-3)" "unprognostic (2.08e-2)" "unprognostic (3.04e-1)" "unprognostic (1.78e-1)" "unprognostic (2.09e-1)" "unprognostic (1.43e-1)" "unprognostic (3.35e-2)" "unprognostic (1.86e-1)" "unprognostic (1.69e-1)" "unprognostic (9.35e-3)" "unprognostic (1.91e-1)" ZNF234 "HZF4, ZNF269" ENSG00000263002 "Zinc finger protein 234" Q14588 19 44141554-44160313 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA001664 Approved Approved "Nuclear bodies" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 61: Non-specific - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" "Nuclear bodies" "HPA001664: " "unprognostic (3.27e-3)" "unprognostic (1.00e-1)" "unprognostic (2.15e-2)" "unprognostic (5.99e-2)" "unprognostic (3.12e-1)" "unprognostic (1.56e-1)" "unprognostic (1.03e-1)" "unprognostic (2.74e-1)" "unprognostic (9.81e-2)" "unprognostic (8.71e-2)" "unprognostic (1.42e-3)" "unprognostic (5.34e-3)" "unprognostic (3.39e-2)" "unprognostic (1.55e-2)" "unprognostic (4.47e-2)" "unprognostic (1.92e-1)" "unprognostic (1.44e-1)" "unprognostic (1.19e-1)" "unprognostic (1.85e-1)" "unprognostic (4.54e-2)" "unprognostic (1.10e-1)" "unprognostic (2.22e-2)" "unprognostic (3.86e-2)" "unprognostic (9.27e-2)" "potential prognostic favorable (3.22e-4)" "unprognostic (2.15e-2)" "unprognostic (2.23e-2)" "unprognostic (1.95e-1)" "unprognostic (1.62e-1)" "unprognostic (2.56e-1)" "unprognostic (8.57e-2)" ZNF235 "ANF270, HZF6, ZFP93, ZNF270" ENSG00000159917 "Zinc finger protein 235" Q14590 19 44228729-44305046 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 148.0;Choroid plexus epithelial cells: 109.9;Ependymal cells: 109.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045582 Uncertain Approved Nucleoplasm NA NA "Cluster 34: B-cells - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 3 Nucleoplasm "HPA045582: " "unprognostic (7.71e-3)" "unprognostic (4.59e-2)" "unprognostic (3.13e-1)" "potential prognostic unfavorable (3.22e-4)" "unprognostic (2.25e-2)" "unprognostic (3.74e-1)" "unprognostic (6.27e-2)" "unprognostic (2.66e-1)" "unprognostic (2.26e-2)" "unprognostic (1.27e-1)" "validated prognostic favorable (2.56e-5)" "validated prognostic favorable (1.28e-5)" "unprognostic (1.14e-1)" "unprognostic (1.76e-2)" "unprognostic (6.39e-3)" "unprognostic (1.18e-1)" "unprognostic (4.53e-3)" "unprognostic (3.55e-1)" "unprognostic (8.20e-2)" "unprognostic (3.13e-1)" "unprognostic (2.58e-1)" "unprognostic (2.03e-2)" "unprognostic (2.02e-2)" "unprognostic (2.73e-2)" "unprognostic (6.83e-2)" "unprognostic (1.76e-1)" "unprognostic (1.16e-1)" "unprognostic (9.72e-2)" "unprognostic (5.38e-2)" "unprognostic (1.77e-1)" "unprognostic (1.32e-1)" ZNF236 ENSG00000130856 "Zinc finger protein 236" Q9UL36 18 76822557-76972901 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008600 Uncertain Approved "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 39: Testis - Nuclear processes" "Cluster 34: Non-specific - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 7: Non-specific - Transcription" 1 "Nucleoplasm, Cell Junctions" Cytosol "HPA008600: " "unprognostic (1.98e-2)" "unprognostic (1.95e-1)" "unprognostic (3.33e-1)" "unprognostic (5.70e-3)" "unprognostic (1.59e-1)" "unprognostic (1.27e-1)" "unprognostic (2.43e-1)" "potential prognostic favorable (3.17e-4)" "unprognostic (9.33e-3)" "unprognostic (1.89e-1)" "unprognostic (2.97e-3)" "unprognostic (9.76e-3)" "unprognostic (1.61e-1)" "unprognostic (1.50e-1)" "unprognostic (8.60e-2)" "unprognostic (3.47e-2)" "unprognostic (1.83e-1)" "unprognostic (1.82e-1)" "unprognostic (1.75e-1)" "unprognostic (2.65e-1)" "unprognostic (1.99e-1)" "unprognostic (8.37e-3)" "unprognostic (3.33e-1)" "unprognostic (2.48e-2)" "unprognostic (8.49e-2)" "unprognostic (2.33e-2)" "unprognostic (2.56e-1)" "unprognostic (1.83e-1)" "unprognostic (8.67e-3)" "unprognostic (3.65e-2)" ZNF239 "HOK-2, MOK2" ENSG00000196793 "Zinc finger protein 239" Q16600 10 43556344-43574618 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 32.4;Late primary spermatocytes: 47.1;Late spermatids: 20.0;Oocytes: 13.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 10 "B-cells: 2.8;T-cells: 6.4" "Low cancer specificity" "Detected in all" "Skin - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030843, HPA046679" Uncertain Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 21: Testis - Mixed function" "Cluster 34: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" 8 "Nuclear bodies" Nucleoplasm "HPA030843: , HPA046679: " "unprognostic (1.99e-1)" "unprognostic (1.03e-2)" "unprognostic (1.44e-1)" "unprognostic (1.04e-2)" "unprognostic (7.97e-2)" "unprognostic (6.13e-2)" "unprognostic (2.64e-2)" "potential prognostic favorable (9.49e-4)" "unprognostic (1.79e-1)" "unprognostic (3.06e-1)" "unprognostic (3.84e-2)" "potential prognostic unfavorable (2.30e-4)" "potential prognostic unfavorable (6.60e-8)" "unprognostic (4.07e-3)" "unprognostic (9.74e-2)" "unprognostic (2.83e-3)" "unprognostic (8.48e-2)" "unprognostic (1.65e-1)" "unprognostic (3.43e-2)" "unprognostic (2.52e-1)" "unprognostic (1.34e-1)" "unprognostic (3.20e-1)" "unprognostic (2.87e-2)" "unprognostic (7.73e-2)" "unprognostic (1.53e-1)" "unprognostic (2.96e-1)" "unprognostic (1.20e-1)" "unprognostic (3.31e-1)" "unprognostic (1.97e-1)" "unprognostic (1.78e-1)" ZNF24 "KOX17, Zfp191, ZNF191, ZSCAN3" ENSG00000172466 "Zinc finger protein 24" P17028 18 35332227-35345482 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024062, CAB025642" Supported Supported Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 17: Non-specific - RNA processing" 72 Nucleoplasm "CAB025642: , HPA024062: " "unprognostic (1.06e-2)" "unprognostic (6.58e-2)" "unprognostic (4.28e-1)" "unprognostic (4.57e-2)" "unprognostic (5.41e-2)" "unprognostic (2.14e-1)" "unprognostic (5.96e-2)" "unprognostic (3.12e-3)" "unprognostic (2.72e-2)" "potential prognostic unfavorable (6.83e-4)" "validated prognostic favorable (4.03e-6)" "validated prognostic favorable (3.09e-4)" "unprognostic (4.11e-3)" "unprognostic (5.89e-2)" "unprognostic (2.21e-1)" "unprognostic (2.08e-2)" "unprognostic (1.95e-2)" "unprognostic (1.83e-1)" "unprognostic (4.94e-3)" "unprognostic (2.98e-1)" "unprognostic (1.48e-1)" "unprognostic (2.97e-1)" "unprognostic (2.19e-1)" "unprognostic (3.94e-2)" "unprognostic (9.78e-2)" "unprognostic (5.93e-2)" "unprognostic (6.65e-2)" "unprognostic (2.07e-1)" "unprognostic (1.51e-2)" "unprognostic (1.28e-1)" "unprognostic (2.71e-1)" ZNF248 bA162G10.3 ENSG00000198105 "Zinc finger protein 248" Q8NDW4 10 37776526-37858106 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Lactotrophs: 264.6;Somatotrophs: 245.2;Thyrotrophs: 278.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018237, HPA018287, HPA018455" Uncertain Approved Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" Nucleoplasm "HPA018237: , HPA018287: , HPA018455: " "unprognostic (1.32e-2)" "unprognostic (1.25e-2)" "unprognostic (8.94e-2)" "unprognostic (2.53e-1)" "potential prognostic unfavorable (8.19e-5)" "unprognostic (1.29e-1)" "unprognostic (3.75e-3)" "potential prognostic favorable (1.45e-5)" "unprognostic (2.51e-2)" "unprognostic (1.35e-2)" "unprognostic (4.54e-2)" "unprognostic (1.93e-2)" "unprognostic (1.23e-1)" "potential prognostic unfavorable (8.81e-5)" "unprognostic (1.68e-1)" "potential prognostic favorable (2.39e-4)" "unprognostic (2.78e-1)" "unprognostic (3.01e-1)" "unprognostic (3.58e-1)" "unprognostic (1.89e-1)" "unprognostic (1.19e-1)" "unprognostic (5.97e-3)" "unprognostic (3.91e-3)" "unprognostic (3.69e-1)" "unprognostic (2.57e-3)" "unprognostic (1.29e-1)" "unprognostic (4.23e-3)" "unprognostic (2.71e-1)" "unprognostic (4.33e-1)" "unprognostic (3.80e-2)" "unprognostic (2.58e-1)" ZNF25 "FLJ31890, KOX19, Zfp9" ENSG00000175395 "Zinc finger protein 25" P17030 10 37949573-37976647 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Lactotrophs: 68.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030190 Uncertain Approved "Nucleoplasm,Golgi apparatus" No No "Cluster 42: Non-specific - Vesicular transport" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 1: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" "Nucleoplasm, Golgi apparatus" "HPA030190: " "unprognostic (9.54e-3)" "unprognostic (8.30e-2)" "unprognostic (4.15e-2)" "unprognostic (3.50e-2)" "unprognostic (1.61e-2)" "unprognostic (3.29e-1)" "unprognostic (1.46e-1)" "potential prognostic favorable (5.28e-4)" "unprognostic (1.63e-2)" "unprognostic (1.36e-1)" "potential prognostic favorable (9.90e-5)" "unprognostic (1.68e-2)" "unprognostic (3.37e-1)" "unprognostic (3.54e-2)" "unprognostic (2.42e-1)" "unprognostic (1.03e-3)" "unprognostic (1.32e-1)" "unprognostic (1.72e-1)" "unprognostic (3.50e-2)" "unprognostic (1.65e-1)" "unprognostic (1.26e-2)" "unprognostic (1.31e-3)" "unprognostic (2.79e-1)" "unprognostic (2.20e-1)" "unprognostic (4.15e-2)" "unprognostic (2.09e-1)" "unprognostic (5.27e-2)" "unprognostic (3.45e-2)" "unprognostic (1.24e-1)" "potential prognostic unfavorable (4.84e-4)" "unprognostic (1.50e-1)" ZNF250 "MGC9718, ZFP647, ZNF647" ENSG00000196150 "Zinc finger protein 250" P15622 8 144876497-144902168 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 95.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020853 Uncertain Approved "Nuclear speckles,Cytosol" NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 64: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 40: Non-specific - Unknown function" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 5 "Nuclear speckles" Cytosol "HPA020853: " "unprognostic (9.23e-3)" "unprognostic (1.54e-2)" "unprognostic (2.84e-1)" "unprognostic (1.08e-1)" "unprognostic (5.45e-2)" "potential prognostic unfavorable (6.38e-4)" "unprognostic (4.47e-2)" "potential prognostic favorable (1.60e-5)" "unprognostic (1.07e-2)" "unprognostic (1.67e-1)" "validated prognostic favorable (1.67e-4)" "validated prognostic favorable (7.37e-4)" "unprognostic (4.30e-2)" "unprognostic (3.02e-3)" "unprognostic (9.35e-2)" "unprognostic (1.64e-1)" "unprognostic (3.55e-2)" "unprognostic (1.18e-1)" "unprognostic (6.14e-2)" "unprognostic (2.44e-1)" "unprognostic (1.74e-1)" "unprognostic (1.57e-1)" "unprognostic (1.66e-2)" "unprognostic (8.46e-2)" "unprognostic (7.84e-2)" "unprognostic (3.90e-1)" "unprognostic (3.13e-1)" "unprognostic (2.07e-1)" "unprognostic (1.12e-1)" "unprognostic (9.28e-3)" "unprognostic (1.81e-1)" ZNF251 ENSG00000198169 "Zinc finger protein 251" Q9BRH9 8 144720907-144756417 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 49.5;Bergmann glia: 55.1;Brain excitatory neurons: 75.2;Brain inhibitory neurons: 75.8;Choroid plexus epithelial cells: 64.3;Distal convoluted tubule cells: 72.9;Ependymal cells: 33.7;Loop of henle epithelial cells: 66.7;Microglia: 51.8;Oligodendrocyte progenitor cells: 53.1;Oligodendrocytes: 52.8;Other brain neurons: 56.4;Papillary tip epithelial cells: 53.3;Podocytes: 51.6;Proximal tubule cells: 79.0;Renal collecting duct intercalated cells: 62.6;Renal collecting duct principal cells: 59.8;Renal connecting tubule cells: 71.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018290 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 64: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 40: Non-specific - Unknown function" "Cluster 102: Non-specific - Mixed function" 3 Nucleoplasm Cytosol "HPA018290: " "potential prognostic favorable (1.65e-4)" "unprognostic (8.59e-3)" "unprognostic (2.73e-1)" "unprognostic (4.62e-2)" "unprognostic (3.58e-1)" "unprognostic (1.12e-1)" "unprognostic (8.83e-2)" "potential prognostic favorable (6.85e-4)" "unprognostic (1.04e-1)" "unprognostic (2.02e-1)" "unprognostic (8.67e-3)" "unprognostic (2.10e-1)" "unprognostic (2.01e-1)" "unprognostic (2.30e-3)" "unprognostic (2.17e-1)" "unprognostic (2.39e-1)" "unprognostic (1.99e-1)" "unprognostic (8.06e-3)" "unprognostic (1.41e-1)" "unprognostic (2.47e-1)" "unprognostic (3.18e-1)" "unprognostic (1.62e-1)" "potential prognostic unfavorable (4.89e-5)" "unprognostic (4.45e-1)" "unprognostic (1.11e-1)" "unprognostic (6.26e-3)" "unprognostic (1.95e-1)" "unprognostic (1.71e-1)" "unprognostic (7.55e-2)" "unprognostic (2.70e-2)" "unprognostic (1.83e-1)" ZNF253 "BMZF-1, FLJ90391, ZNF411" ENSG00000256771 "Zinc finger protein 253" O75346 19 19865882-19894674 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 72.8;Corticotrophs: 70.4;Myonuclei: 113.0;Rod photoreceptor cells: 113.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 79: Photoreceptor cells - Phototransduction" 1 "unprognostic (3.22e-3)" "unprognostic (1.27e-1)" "unprognostic (2.52e-1)" "unprognostic (3.79e-1)" "unprognostic (1.44e-1)" "unprognostic (2.38e-2)" "unprognostic (4.74e-2)" "unprognostic (2.09e-2)" "unprognostic (2.53e-2)" "unprognostic (2.17e-3)" "potential prognostic favorable (9.52e-6)" "unprognostic (9.01e-3)" "unprognostic (2.56e-1)" "unprognostic (1.67e-2)" "unprognostic (2.90e-2)" "potential prognostic favorable (1.77e-4)" "unprognostic (2.17e-1)" "unprognostic (2.02e-1)" "unprognostic (5.55e-2)" "unprognostic (1.65e-1)" "unprognostic (1.90e-2)" "unprognostic (2.91e-2)" "unprognostic (2.11e-1)" "unprognostic (1.03e-1)" "potential prognostic favorable (9.08e-4)" "unprognostic (7.48e-2)" "unprognostic (1.58e-3)" "unprognostic (8.55e-2)" "unprognostic (2.59e-1)" "unprognostic (1.12e-2)" "unprognostic (4.33e-1)" ZNF254 "BMZF-5, HD-ZNF1, ZNF539, ZNF91L" ENSG00000213096 "Zinc finger protein 254" O75437 19 24033405-24129968 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 256.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" NA NA "Cluster 32: Basophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 24: Neutrophils - Innate immunity signal integration" "potential prognostic favorable (7.40e-5)" "unprognostic (1.75e-2)" "unprognostic (4.41e-1)" "unprognostic (1.66e-1)" "unprognostic (1.42e-1)" "unprognostic (1.04e-2)" "unprognostic (1.61e-1)" "unprognostic (8.17e-2)" "unprognostic (3.56e-1)" "unprognostic (3.02e-2)" "potential prognostic favorable (9.30e-4)" "unprognostic (8.02e-2)" "unprognostic (2.72e-3)" "unprognostic (1.71e-1)" "unprognostic (2.65e-1)" "unprognostic (1.63e-3)" "unprognostic (1.76e-1)" "unprognostic (4.96e-2)" "unprognostic (3.24e-1)" "unprognostic (1.03e-1)" "unprognostic (2.41e-3)" "unprognostic (9.24e-3)" "unprognostic (2.96e-2)" "unprognostic (1.19e-2)" "unprognostic (6.77e-3)" "unprognostic (2.30e-1)" "unprognostic (1.64e-3)" "unprognostic (3.53e-2)" "unprognostic (1.16e-1)" "unprognostic (8.21e-2)" "unprognostic (3.68e-1)" ZNF256 BMZF-3 ENSG00000152454 "Zinc finger protein 256" Q9Y2P7 19 57940833-57947706 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Oocytes: 41.4" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 20.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" HPA055390 Uncertain Supported Nucleoplasm NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 40: Non-specific - Mixed function" "Cluster 35: Non-specific - DNA binding" "Cluster 4: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 1 Nucleoplasm "HPA055390: " "unprognostic (2.83e-2)" "unprognostic (4.80e-2)" "unprognostic (1.06e-1)" "potential prognostic unfavorable (3.92e-4)" "unprognostic (4.06e-2)" "unprognostic (2.38e-1)" "unprognostic (2.87e-2)" "unprognostic (3.80e-2)" "unprognostic (2.55e-1)" "unprognostic (4.13e-2)" "validated prognostic favorable (5.24e-4)" "validated prognostic favorable (5.33e-4)" "unprognostic (1.48e-2)" "unprognostic (2.42e-1)" "unprognostic (8.42e-2)" "unprognostic (1.80e-1)" "unprognostic (3.22e-2)" "unprognostic (1.08e-1)" "unprognostic (1.96e-2)" "unprognostic (7.39e-2)" "unprognostic (1.26e-1)" "unprognostic (3.41e-3)" "unprognostic (1.42e-2)" "unprognostic (1.08e-2)" "unprognostic (1.73e-1)" "unprognostic (1.28e-1)" "potential prognostic unfavorable (6.91e-4)" "unprognostic (6.40e-3)" "unprognostic (6.78e-2)" "unprognostic (1.55e-1)" "unprognostic (1.02e-1)" ZNF257 BMZF-4 ENSG00000197134 "Zinc finger protein 257" Q9Y2Q1 19 22052430-22091480 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 34.6;Megakaryocytes: 55.6;Neutrophils: 40.6;Platelets: 119.9" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 5.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Spermatocytes" NA NA "Cluster 32: Basophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 30: White matter - Myelination" "Cluster 4: Non-specific - Transcription" "Cluster 29: Neutrophils - Innate immune cellular maintenance" "unprognostic (2.63e-1)" "unprognostic (9.58e-2)" "unprognostic (1.88e-1)" "unprognostic (1.56e-1)" "unprognostic (2.19e-1)" "unprognostic (9.81e-2)" "unprognostic (2.25e-3)" "unprognostic (1.07e-1)" "unprognostic (2.93e-1)" "unprognostic (6.35e-2)" "unprognostic (2.12e-3)" "unprognostic (1.37e-1)" "unprognostic (9.05e-2)" "unprognostic (5.27e-2)" "unprognostic (3.56e-1)" "unprognostic (1.23e-1)" ZNF26 "FLJ20755, KOX20" ENSG00000198393 "Zinc finger protein 26" P17031 12 132986365-133032952 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "HPA018329, HPA042406" Uncertain Approved "Nuclear bodies,Mitochondria" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 40: Non-specific - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 4 Mitochondria "Nuclear bodies" "HPA018329: , HPA042406: " "unprognostic (1.03e-2)" "unprognostic (4.21e-2)" "unprognostic (3.07e-1)" "unprognostic (3.15e-3)" "unprognostic (1.29e-2)" "unprognostic (7.01e-2)" "unprognostic (2.82e-1)" "unprognostic (6.02e-2)" "unprognostic (1.34e-2)" "unprognostic (1.95e-3)" "potential prognostic favorable (7.52e-4)" "unprognostic (1.39e-1)" "unprognostic (1.84e-1)" "unprognostic (5.60e-2)" "unprognostic (2.94e-1)" "unprognostic (1.45e-1)" "unprognostic (1.11e-2)" "unprognostic (1.62e-1)" "unprognostic (1.61e-1)" "unprognostic (4.82e-2)" "unprognostic (2.36e-1)" "unprognostic (1.14e-2)" "unprognostic (1.39e-3)" "unprognostic (8.03e-3)" "unprognostic (4.04e-2)" "unprognostic (4.55e-2)" "unprognostic (1.59e-1)" "unprognostic (3.31e-3)" "unprognostic (1.59e-1)" ZNF260 "ozrf1, Zfp260" ENSG00000254004 "Zinc finger protein 260" Q3ZCT1 19 36510687-36528271 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028806 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 3 "Nucleoplasm, Cytosol" "HPA028806: " "unprognostic (2.25e-3)" "unprognostic (5.35e-2)" "unprognostic (8.19e-2)" "unprognostic (1.78e-1)" "unprognostic (8.33e-2)" "unprognostic (2.85e-1)" "unprognostic (3.15e-2)" "unprognostic (4.09e-2)" "unprognostic (3.86e-3)" "unprognostic (9.69e-3)" "potential prognostic favorable (2.31e-5)" "unprognostic (6.04e-3)" "unprognostic (2.43e-2)" "unprognostic (9.72e-3)" "unprognostic (1.54e-1)" "unprognostic (4.95e-2)" "unprognostic (4.06e-1)" "unprognostic (4.32e-2)" "unprognostic (2.38e-1)" "unprognostic (7.79e-2)" "unprognostic (1.37e-2)" "unprognostic (1.27e-1)" "unprognostic (1.21e-2)" "unprognostic (3.87e-2)" "unprognostic (1.69e-3)" "unprognostic (9.74e-2)" "unprognostic (1.81e-2)" "unprognostic (1.09e-1)" "unprognostic (1.32e-1)" "unprognostic (7.01e-2)" "unprognostic (1.49e-1)" ZNF263 "FPM315, ZKSCAN12, ZSCAN44" ENSG00000006194 "Zinc finger protein 263" O14978 16 3283283-3301401 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 51.8;Late primary spermatocytes: 64.1;Late spermatids: 44.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035085, HPA035086" Approved Supported "Nucleoplasm,Mitotic spindle,Cytosol" Yes No "Cluster 45: Eosinophils - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 54: Non-specific - Transcription" "Cluster 103: Non-specific - Basic cellular processes" 26 Cytosol "Nucleoplasm, Mitotic spindle" "HPA035085: , HPA035086: " "unprognostic (9.67e-3)" "unprognostic (2.61e-2)" "unprognostic (1.82e-1)" "unprognostic (1.47e-1)" "unprognostic (3.67e-2)" "unprognostic (5.10e-2)" "unprognostic (2.97e-1)" "unprognostic (1.43e-3)" "unprognostic (1.21e-1)" "unprognostic (2.55e-2)" "potential prognostic favorable (3.30e-5)" "unprognostic (7.07e-3)" "unprognostic (3.99e-1)" "unprognostic (1.77e-2)" "unprognostic (2.81e-2)" "unprognostic (2.37e-1)" "unprognostic (2.76e-1)" "unprognostic (3.50e-1)" "potential prognostic favorable (7.00e-4)" "unprognostic (1.27e-1)" "unprognostic (2.04e-1)" "unprognostic (3.12e-2)" "unprognostic (1.84e-1)" "unprognostic (3.35e-2)" "unprognostic (3.21e-3)" "unprognostic (2.23e-1)" "unprognostic (1.86e-1)" "unprognostic (1.69e-1)" "unprognostic (2.24e-1)" "unprognostic (6.20e-3)" "unprognostic (6.74e-2)" ZNF264 KIAA0412 ENSG00000083844 "Zinc finger protein 264" O43296 19 57191500-57222846 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" HPA046330 Approved Nucleoplasm NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 19 Nucleoplasm "HPA046330: " "unprognostic (2.10e-3)" "unprognostic (1.63e-1)" "unprognostic (4.29e-2)" "unprognostic (3.19e-3)" "unprognostic (7.47e-2)" "unprognostic (1.27e-2)" "unprognostic (7.20e-2)" "unprognostic (3.70e-2)" "unprognostic (1.41e-2)" "unprognostic (1.06e-2)" "unprognostic (3.04e-2)" "potential prognostic favorable (4.79e-4)" "unprognostic (7.62e-3)" "unprognostic (9.60e-2)" "unprognostic (6.24e-2)" "unprognostic (1.75e-1)" "unprognostic (8.45e-2)" "unprognostic (2.50e-2)" "unprognostic (6.88e-2)" "unprognostic (3.48e-2)" "unprognostic (2.98e-1)" "unprognostic (3.31e-1)" "unprognostic (6.37e-2)" "unprognostic (2.01e-1)" "unprognostic (1.15e-1)" "unprognostic (3.71e-3)" "unprognostic (3.05e-2)" "unprognostic (6.58e-2)" "unprognostic (1.31e-1)" "unprognostic (7.47e-2)" "unprognostic (2.38e-2)" ZNF266 HZF1 ENSG00000174652 "Zinc finger protein 266" Q14584 19 9412429-9435573 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026836, HPA054110" Uncertain Supported "Nucleoplasm,Vesicles,Rods & Rings" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 49: Non-specific - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 9 Vesicles "Nucleoplasm, Rods & Rings" "HPA026836: , HPA054110: " "potential prognostic favorable (3.31e-4)" "unprognostic (3.26e-1)" "unprognostic (1.26e-1)" "unprognostic (2.40e-2)" "unprognostic (4.30e-2)" "unprognostic (8.03e-2)" "unprognostic (2.32e-1)" "unprognostic (2.01e-2)" "potential prognostic favorable (1.91e-5)" "unprognostic (8.66e-2)" "unprognostic (7.31e-3)" "unprognostic (1.49e-1)" "unprognostic (7.79e-3)" "unprognostic (8.06e-3)" "unprognostic (1.80e-1)" "potential prognostic favorable (2.86e-4)" "unprognostic (6.45e-2)" "unprognostic (8.29e-2)" "unprognostic (1.02e-1)" "unprognostic (3.25e-2)" "unprognostic (7.30e-2)" "potential prognostic favorable (8.45e-5)" "unprognostic (6.78e-3)" "unprognostic (2.07e-2)" "unprognostic (1.14e-1)" "unprognostic (2.35e-1)" "unprognostic (1.09e-1)" "unprognostic (8.57e-2)" "unprognostic (2.59e-2)" "unprognostic (2.68e-1)" "unprognostic (3.31e-2)" ZNF267 HZF2 ENSG00000185947 "Zinc finger protein 267" Q14586 16 31873807-31917357 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "cDC: 153.7;Macrophages: 151.6;monocytes: 280.1;Neutrophils: 640.2" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 71.1;leukocyte: 56.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" HPA003866 Approved Approved Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 55: Lymphoma - Immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 4 Nucleoplasm "HPA003866: " "unprognostic (1.11e-1)" "unprognostic (1.19e-1)" "unprognostic (3.15e-2)" "potential prognostic unfavorable (2.93e-4)" "unprognostic (6.25e-2)" "unprognostic (6.31e-2)" "unprognostic (3.68e-2)" "unprognostic (1.36e-1)" "unprognostic (5.03e-2)" "unprognostic (9.94e-2)" "unprognostic (1.86e-2)" "unprognostic (4.90e-1)" "unprognostic (3.78e-2)" "unprognostic (1.41e-2)" "unprognostic (1.13e-1)" "unprognostic (2.83e-1)" "potential prognostic unfavorable (9.40e-4)" "unprognostic (9.83e-2)" "unprognostic (2.62e-1)" "unprognostic (2.96e-2)" "unprognostic (4.44e-3)" "unprognostic (1.17e-2)" "unprognostic (5.77e-3)" "unprognostic (2.06e-2)" "unprognostic (1.35e-1)" "unprognostic (6.31e-2)" "unprognostic (1.01e-1)" "unprognostic (2.46e-1)" "unprognostic (3.21e-1)" "unprognostic (1.59e-1)" "unprognostic (5.53e-2)" ZNF268 HZF3 ENSG00000090612 "Zinc finger protein 268" Q14587 12 133181409-133214832 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" HPA001794 Approved Approved Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 61: Non-specific - Transcription" "Cluster 5: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 5 Cytosol "HPA001794: " "unprognostic (3.01e-1)" "unprognostic (8.16e-2)" "unprognostic (1.33e-1)" "unprognostic (2.70e-3)" "unprognostic (2.40e-2)" "unprognostic (1.89e-1)" "unprognostic (1.12e-1)" "unprognostic (3.46e-1)" "unprognostic (1.28e-1)" "unprognostic (5.92e-3)" "potential prognostic favorable (3.99e-6)" "unprognostic (2.12e-2)" "unprognostic (2.31e-1)" "unprognostic (1.93e-1)" "unprognostic (9.92e-2)" "unprognostic (2.66e-1)" "unprognostic (1.90e-1)" "unprognostic (1.69e-2)" "unprognostic (1.54e-1)" "unprognostic (4.10e-2)" "unprognostic (2.10e-2)" "unprognostic (3.30e-1)" "unprognostic (1.04e-2)" "unprognostic (4.18e-2)" "unprognostic (2.70e-2)" "unprognostic (1.87e-1)" "unprognostic (1.30e-2)" "unprognostic (3.09e-2)" "unprognostic (2.62e-1)" "unprognostic (1.68e-1)" "unprognostic (2.89e-1)" ZNF273 HZF9 ENSG00000198039 "Zinc finger protein 273" Q14593 7 64870172-64930981 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.7" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 203.8;Ependymal cells: 321.1;Erythrocyte progenitors: 78.9;Fallopian tube ciliated cells: 81.7;Respiratory ciliated cells: 135.3" "Cell type enhanced" "Detected in all" "ependymal cell: 329.2" "Cancer enriched" "Detected in some" 6 "Testicular Germ Cell Tumor (TCGA): 7.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Testis - Early spermatids" HPA077549 Approved Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 2: Non-specific - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 4: Non-specific - Transcription" "Cluster 34: Ciliated cells - Cilia assembly & function" 4 Nucleoplasm "HPA077549: " "unprognostic (7.99e-3)" "unprognostic (9.78e-2)" "unprognostic (2.32e-2)" "unprognostic (1.59e-3)" "unprognostic (2.66e-1)" "unprognostic (1.95e-1)" "unprognostic (1.69e-2)" "unprognostic (5.29e-1)" ZNF274 "ZKSCAN19, ZSCAN51" ENSG00000171606 "Zinc finger protein 274" Q96GC6 19 58183029-58213562 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028880 Uncertain Approved Nucleoplasm,Centrosome NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 55: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 4 Nucleoplasm Centrosome "HPA028880: " "unprognostic (1.29e-1)" "unprognostic (1.79e-1)" "unprognostic (7.88e-2)" "unprognostic (8.07e-2)" "unprognostic (1.35e-1)" "unprognostic (1.06e-1)" "unprognostic (3.47e-2)" "potential prognostic favorable (5.69e-4)" "unprognostic (7.13e-3)" "unprognostic (9.80e-2)" "validated prognostic favorable (1.52e-4)" "validated prognostic favorable (4.46e-4)" "unprognostic (2.48e-3)" "unprognostic (2.03e-1)" "unprognostic (4.29e-3)" "unprognostic (7.51e-2)" "unprognostic (3.59e-2)" "unprognostic (1.44e-1)" "unprognostic (1.67e-1)" "unprognostic (1.58e-1)" "unprognostic (1.56e-2)" "unprognostic (1.36e-1)" "unprognostic (2.81e-2)" "unprognostic (1.54e-3)" "unprognostic (4.27e-2)" "unprognostic (2.12e-1)" "unprognostic (3.16e-2)" "unprognostic (3.20e-1)" "unprognostic (1.24e-1)" "unprognostic (1.30e-1)" "unprognostic (3.63e-1)" ZNF275 ENSG00000063587 "Zinc finger protein 275" Q9NSD4 X 153334147-153360110 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 67.9" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 189.7;Adrenal medulla cells: 53.2;Granulosa cells: 56.0;Sertoli cells: 46.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Myeloma: 28.0" "Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Testis - Sertoli cells" HPA000566 Approved Approved Nucleoli NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 22: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 18: Adrenal cortex cells - Steroidogensis" 13 Nucleoli "HPA000566: " "unprognostic (5.75e-2)" "unprognostic (9.99e-3)" "unprognostic (1.32e-2)" "unprognostic (2.61e-1)" "unprognostic (7.50e-2)" "unprognostic (7.42e-2)" "unprognostic (2.44e-1)" "unprognostic (4.63e-2)" "unprognostic (1.03e-1)" "unprognostic (4.02e-2)" "potential prognostic favorable (9.81e-4)" "unprognostic (5.48e-2)" "unprognostic (1.82e-1)" "unprognostic (1.46e-1)" "unprognostic (3.26e-1)" "unprognostic (2.26e-2)" "unprognostic (1.59e-1)" "unprognostic (1.66e-1)" "unprognostic (1.90e-2)" "unprognostic (2.41e-1)" "unprognostic (2.81e-2)" "unprognostic (3.31e-2)" "unprognostic (4.78e-2)" "unprognostic (1.89e-1)" "unprognostic (2.37e-1)" "unprognostic (4.99e-2)" "unprognostic (1.28e-1)" "unprognostic (4.11e-2)" "unprognostic (1.05e-1)" "unprognostic (1.65e-2)" "unprognostic (2.82e-1)" ZNF276 "CENP-Z, CENPZ, MGC45417, ZADT, ZFP276, ZNF477" ENSG00000158805 "Zinc finger protein 276" Q8N554 16 89720400-89740925 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 94.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021309, HPA022255" Uncertain Approved "Nucleoplasm,Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 9 "Nucleoplasm, Cytosol" "Nucleoli, Plasma membrane" "HPA021309: , HPA022255: " "unprognostic (1.99e-1)" "unprognostic (4.59e-2)" "unprognostic (1.47e-2)" "unprognostic (9.99e-2)" "unprognostic (6.22e-3)" "unprognostic (1.94e-3)" "unprognostic (3.00e-1)" "potential prognostic favorable (2.00e-5)" "unprognostic (6.28e-2)" "unprognostic (9.34e-3)" "potential prognostic unfavorable (4.36e-4)" "unprognostic (1.99e-1)" "unprognostic (4.23e-3)" "unprognostic (4.69e-2)" "unprognostic (2.90e-2)" "unprognostic (8.61e-3)" "unprognostic (7.52e-2)" "unprognostic (2.81e-1)" "unprognostic (2.86e-2)" "unprognostic (1.80e-2)" "unprognostic (9.78e-2)" "unprognostic (1.73e-2)" "unprognostic (4.06e-2)" "unprognostic (7.51e-3)" "unprognostic (1.01e-1)" "unprognostic (6.96e-2)" "unprognostic (1.29e-1)" "unprognostic (9.96e-3)" "unprognostic (1.11e-1)" "unprognostic (9.86e-2)" "unprognostic (6.04e-2)" ZNF277 "NRIF4, ZNF277P" ENSG00000198839 "Zinc finger protein 277" Q9NRM2 7 112206695-112343934 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 327.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027307 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 61: Non-specific - Transcription" "Cluster 9: Non-specific - Receptor signaling" "Cluster 39: Non-specific - Transcription" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 3 Nucleoplasm "Plasma membrane" "HPA027307: " "unprognostic (2.84e-2)" "unprognostic (3.00e-1)" "unprognostic (2.71e-1)" "unprognostic (2.33e-2)" "unprognostic (4.28e-2)" "unprognostic (1.64e-2)" "unprognostic (2.50e-1)" "unprognostic (6.76e-2)" "unprognostic (2.94e-2)" "potential prognostic unfavorable (1.56e-4)" "unprognostic (8.23e-3)" "unprognostic (4.60e-3)" "unprognostic (2.31e-2)" "unprognostic (1.21e-2)" "unprognostic (8.90e-2)" "unprognostic (6.92e-2)" "unprognostic (1.33e-1)" "unprognostic (1.01e-1)" "unprognostic (6.16e-2)" "unprognostic (1.49e-1)" "potential prognostic unfavorable (2.28e-4)" "unprognostic (1.04e-1)" "unprognostic (3.79e-1)" "unprognostic (1.03e-1)" "unprognostic (3.25e-1)" "unprognostic (4.06e-1)" "unprognostic (2.81e-2)" "unprognostic (1.03e-1)" "unprognostic (1.76e-1)" "unprognostic (4.72e-2)" "unprognostic (2.54e-1)" ZNF28 "DKFZp781D0275, KOX24" ENSG00000198538 "Zinc finger protein 28" P17035 19 52797408-52857600 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" "unprognostic (9.11e-2)" "unprognostic (1.97e-3)" "unprognostic (1.49e-1)" "unprognostic (5.69e-2)" "unprognostic (1.22e-1)" "unprognostic (5.87e-2)" "unprognostic (1.45e-1)" "unprognostic (6.85e-2)" "unprognostic (1.99e-1)" "unprognostic (1.31e-2)" "potential prognostic favorable (1.26e-6)" "unprognostic (7.83e-2)" "unprognostic (8.24e-2)" "unprognostic (5.27e-3)" "unprognostic (4.64e-3)" "potential prognostic unfavorable (7.14e-5)" "unprognostic (2.60e-2)" "unprognostic (1.59e-3)" "unprognostic (8.35e-2)" "unprognostic (7.34e-2)" "unprognostic (8.47e-3)" "unprognostic (8.49e-3)" "unprognostic (2.49e-1)" "unprognostic (8.84e-2)" "unprognostic (7.57e-2)" "unprognostic (1.26e-1)" "unprognostic (8.86e-3)" "unprognostic (2.61e-1)" "unprognostic (4.88e-2)" "unprognostic (2.91e-1)" "unprognostic (3.18e-1)" ZNF280A "3'OY11.1, SUHW1, ZNF280, ZNF636" ENSG00000169548 "Zinc finger protein 280A" P59817 22 22513736-22520270 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "adrenal gland: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Skin Cutaneous Melanoma (TCGA): 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "skin cancer: 1.1" HPA044475 Approved Nucleoplasm NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 3 Nucleoplasm "HPA044475: " "unprognostic (4.30e-3)" ZNF280B "5'OY11.1, SUHW2, ZNF279, ZNF632" ENSG00000275004 "Zinc finger protein 280B" Q86YH2 22 22484421-22508742 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 12.5" "Cell type enhanced" "Detected in some" "Astrocytes: 8.5;Brain excitatory neurons: 20.3;Brain inhibitory neurons: 21.4;Choroid plexus epithelial cells: 10.6;Differentiating spermatogonia: 16.5;Early primary spermatocytes: 16.8;Early spermatids: 33.2;Late spermatids: 21.5;Medullary thymic epithelial cells: 12.0;Oligodendrocyte progenitor cells: 14.6;Oligodendrocytes: 8.6;Other brain neurons: 25.2;Tuft cells: 11.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059519 Uncertain Approved Nucleoplasm NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 23: Testis - Spermatogenesis" "Cluster 1: Neurons - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 109: Neurons - Neuronal signaling" Nucleoplasm "HPA059519: " "unprognostic (2.54e-1)" "unprognostic (5.53e-3)" "unprognostic (4.00e-2)" "unprognostic (3.79e-2)" "unprognostic (1.02e-1)" "unprognostic (1.55e-2)" "unprognostic (2.64e-3)" "unprognostic (9.25e-2)" "unprognostic (7.69e-2)" "unprognostic (1.86e-1)" "unprognostic (1.73e-1)" "unprognostic (1.42e-1)" "unprognostic (6.98e-2)" "unprognostic (1.27e-1)" ZNF280C "FLJ20095, SUHW3, ZNF633, ZPET" ENSG00000056277 "Zinc finger protein 280C" Q8ND82 X 130202707-130268899 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 8.8" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 64.1;Early primary spermatocytes: 65.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051494, HPA055788" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 22: Epididymis - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 36: Non-specific - mRNA processing" "Cluster 20: Non-specific - Transcription regulation" 21 "Nucleoplasm, Nucleoli fibrillar center" "HPA051494: , HPA055788: " "unprognostic (1.26e-1)" "unprognostic (1.88e-1)" "unprognostic (9.68e-2)" "unprognostic (2.73e-1)" "unprognostic (2.24e-1)" "unprognostic (4.77e-2)" "unprognostic (7.11e-2)" "unprognostic (2.94e-2)" "unprognostic (7.96e-2)" "unprognostic (1.11e-1)" "unprognostic (2.32e-1)" "potential prognostic unfavorable (8.52e-5)" "unprognostic (8.67e-2)" "unprognostic (2.00e-1)" "unprognostic (5.74e-3)" "unprognostic (1.65e-2)" "unprognostic (1.26e-2)" "unprognostic (1.91e-1)" "unprognostic (2.45e-1)" "unprognostic (1.60e-1)" "unprognostic (2.83e-2)" "unprognostic (6.17e-2)" "unprognostic (2.46e-2)" "unprognostic (7.07e-2)" "unprognostic (2.56e-1)" "unprognostic (9.99e-2)" "unprognostic (4.17e-2)" "potential prognostic unfavorable (4.21e-4)" "unprognostic (1.28e-1)" ZNF280D "FLJ20086, SUHW4, ZNF634" ENSG00000137871 "Zinc finger protein 280D" Q6N043 15 56630176-56734086 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 224.3;Bergmann glia: 307.7;Choroid plexus epithelial cells: 252.5;Oligodendrocyte progenitor cells: 267.7;Oligodendrocytes: 334.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030233 Approved Approved "Nucleoplasm,Golgi apparatus,Centrosome,Cytosol" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 28: Astrocytes - Homeostasis & neuron support" 3 "Nucleoplasm, Cytosol" "Golgi apparatus, Centrosome" "HPA030233: " "unprognostic (1.53e-1)" "unprognostic (7.39e-2)" "unprognostic (1.31e-1)" "unprognostic (1.10e-1)" "unprognostic (1.95e-1)" "unprognostic (1.82e-1)" "unprognostic (4.99e-2)" "unprognostic (7.96e-3)" "unprognostic (1.42e-2)" "unprognostic (2.38e-3)" "validated prognostic favorable (7.14e-8)" "validated prognostic favorable (6.42e-4)" "unprognostic (8.15e-2)" "unprognostic (1.28e-1)" "unprognostic (2.64e-3)" "unprognostic (9.49e-2)" "unprognostic (2.62e-1)" "unprognostic (2.03e-1)" "unprognostic (1.54e-1)" "unprognostic (2.86e-1)" "unprognostic (7.30e-2)" "unprognostic (4.13e-2)" "unprognostic (1.98e-2)" "unprognostic (2.21e-1)" "unprognostic (3.56e-1)" "unprognostic (9.27e-2)" "unprognostic (1.70e-2)" "unprognostic (1.97e-1)" "unprognostic (7.97e-2)" "unprognostic (1.34e-2)" "unprognostic (8.91e-2)" ZNF281 ZBP-99 ENSG00000162702 "Zinc finger protein 281" Q9Y2X9 1 200404940-200410056 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 31.7" "Cell type enriched" "Detected in many" 4 "Neutrophils: 385.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051228 Uncertain Enhanced Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 11: White matter - Signal transduction" "Cluster 45: Non-specific - Nuclear processes" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 19 Nucleoplasm "HPA051228: " "unprognostic (2.35e-2)" "unprognostic (2.49e-1)" "unprognostic (3.28e-2)" "potential prognostic unfavorable (9.67e-5)" "unprognostic (3.22e-1)" "unprognostic (3.85e-1)" "unprognostic (2.04e-1)" "potential prognostic favorable (6.91e-4)" "unprognostic (1.19e-1)" "unprognostic (6.57e-2)" "unprognostic (1.80e-2)" "unprognostic (1.92e-1)" "potential prognostic unfavorable (1.00e-4)" "unprognostic (1.91e-1)" "unprognostic (7.71e-2)" "unprognostic (1.74e-2)" "unprognostic (1.20e-1)" "unprognostic (2.07e-2)" "unprognostic (4.65e-1)" "unprognostic (8.42e-2)" "unprognostic (1.12e-3)" "unprognostic (1.17e-2)" "potential prognostic unfavorable (1.82e-4)" "unprognostic (1.98e-2)" "unprognostic (1.67e-1)" "unprognostic (5.29e-2)" "unprognostic (3.03e-2)" "unprognostic (1.38e-2)" "unprognostic (3.09e-1)" "unprognostic (8.57e-3)" "unprognostic (1.82e-2)" ZNF282 HUB1 ENSG00000170265 "Zinc finger protein 282" Q9UDV7 7 149195546-149226238 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024374 Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 24: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 39: Non-specific - Transcription" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 3 Nucleoplasm Cytosol "HPA024374: " "unprognostic (3.27e-1)" "unprognostic (2.70e-1)" "unprognostic (2.06e-1)" "potential prognostic unfavorable (2.93e-4)" "unprognostic (7.33e-2)" "unprognostic (1.13e-2)" "unprognostic (2.06e-1)" "unprognostic (3.19e-2)" "unprognostic (2.14e-1)" "unprognostic (4.84e-3)" "unprognostic (3.37e-2)" "unprognostic (9.31e-2)" "unprognostic (8.34e-2)" "potential prognostic unfavorable (1.76e-6)" "unprognostic (1.17e-2)" "unprognostic (1.88e-2)" "potential prognostic unfavorable (1.39e-4)" "unprognostic (1.78e-1)" "unprognostic (7.93e-2)" "unprognostic (2.03e-1)" "unprognostic (4.37e-1)" "unprognostic (1.18e-2)" "unprognostic (3.66e-1)" "unprognostic (5.58e-2)" "unprognostic (2.20e-1)" "unprognostic (1.90e-1)" "unprognostic (5.68e-2)" "unprognostic (1.07e-3)" "unprognostic (1.49e-1)" "unprognostic (8.36e-2)" "unprognostic (1.04e-2)" ZNF283 ENSG00000167637 "Zinc finger protein 283" Q8N7M2 19 43827321-43852017 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Tuft cells: 57.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072977 Approved Nucleoplasm NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" Nucleoplasm "HPA072977: " "unprognostic (7.43e-2)" "unprognostic (1.33e-1)" "unprognostic (2.95e-1)" "unprognostic (2.37e-2)" "unprognostic (6.10e-2)" "unprognostic (1.77e-1)" "unprognostic (7.24e-2)" "unprognostic (1.66e-1)" "unprognostic (1.49e-2)" "unprognostic (5.21e-2)" "unprognostic (5.15e-3)" "unprognostic (1.53e-2)" "unprognostic (3.37e-1)" "unprognostic (9.01e-3)" "unprognostic (2.61e-1)" "unprognostic (1.66e-1)" "unprognostic (2.73e-1)" "unprognostic (4.26e-2)" "unprognostic (6.13e-2)" "unprognostic (6.93e-3)" "unprognostic (2.05e-1)" "unprognostic (3.78e-2)" "unprognostic (1.78e-1)" "potential prognostic favorable (2.43e-4)" "unprognostic (1.51e-1)" "unprognostic (2.79e-2)" "unprognostic (8.19e-2)" "unprognostic (3.05e-1)" "unprognostic (2.65e-2)" "unprognostic (3.32e-1)" ZNF284 DKFZp781F1775 ENSG00000186026 "Zinc finger protein 284" Q2VY69 19 44072159-44089613 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 6.9;Hepatic stellate cells: 6.5;Megakaryocytes: 6.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 49: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 98: Neurons - Neurotransmission & signaling" 3 "unprognostic (8.96e-3)" "unprognostic (2.15e-2)" "unprognostic (4.33e-1)" "unprognostic (1.81e-2)" "unprognostic (8.99e-2)" "unprognostic (1.79e-1)" "unprognostic (3.96e-2)" "unprognostic (1.16e-1)" "unprognostic (3.06e-2)" "unprognostic (3.20e-3)" "unprognostic (3.02e-3)" "unprognostic (1.34e-1)" "unprognostic (3.15e-1)" "unprognostic (1.10e-1)" "unprognostic (1.01e-2)" "unprognostic (1.15e-1)" "unprognostic (1.23e-1)" "unprognostic (6.05e-2)" "unprognostic (8.37e-2)" "unprognostic (7.41e-3)" "unprognostic (1.32e-2)" "unprognostic (8.96e-2)" "unprognostic (1.50e-2)" "unprognostic (3.24e-2)" "unprognostic (1.45e-1)" "unprognostic (6.71e-2)" "unprognostic (7.72e-2)" ZNF285 ZNF285A ENSG00000267508 "Zinc finger protein 285" Q96NJ3 19 44382298-44401608 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 6 "Astrocytes: 8.9;Bergmann glia: 14.1;Brain excitatory neurons: 10.4;Brain inhibitory neurons: 11.0;Choroid plexus epithelial cells: 3.9;Ependymal cells: 5.5;Oligodendrocyte progenitor cells: 12.8;Oligodendrocytes: 9.5;Oocytes: 4.6;Other brain neurons: 12.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 4.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "HPA046100, HPA049212" Uncertain NA NA "Cluster 32: Basophils - Transcription" "Cluster 65: Brain - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 98: Neurons - Neurotransmission & signaling" 1 "HPA046100: , HPA049212: " "unprognostic (1.76e-1)" "unprognostic (1.17e-1)" "unprognostic (5.57e-2)" "unprognostic (1.97e-2)" "unprognostic (4.93e-2)" "unprognostic (5.67e-2)" "unprognostic (1.60e-1)" "unprognostic (5.60e-3)" "potential prognostic favorable (1.17e-4)" "unprognostic (1.34e-3)" "unprognostic (1.74e-1)" "unprognostic (3.64e-2)" "unprognostic (1.68e-1)" "unprognostic (8.52e-2)" "unprognostic (7.69e-2)" "unprognostic (1.36e-2)" "unprognostic (1.83e-1)" "unprognostic (2.81e-1)" "unprognostic (3.45e-2)" "unprognostic (8.58e-3)" "unprognostic (5.78e-2)" "unprognostic (1.34e-1)" "unprognostic (1.19e-1)" "unprognostic (1.29e-1)" ZNF286A "KIAA1874, ZNF286" ENSG00000187607 "Zinc finger protein 286A" Q9HBT8 17 15699577-15720787 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Early spermatids: 4.6;Epididymal basal cells: 1.5;Epididymal efferent duct ciliated cells: 2.1;Epididymal principal cells: 1.9;Late spermatids: 6.2;Medullary thymic epithelial cells: 2.4;Respiratory deuterosomal cells: 1.0;Respiratory ionocytes: 2.5" "Cell type enhanced" "Detected in some" "medium spiny neuron: 2.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "testis cancer: 111.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021594 Approved Nucleoli No No "Cluster 43: Non-specific - Transcription & Translation" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 13 Nucleoli "HPA021594: " "unprognostic (1.00e-1)" "unprognostic (1.44e-1)" "unprognostic (9.22e-2)" "unprognostic (7.22e-2)" "unprognostic (4.12e-1)" "unprognostic (6.67e-2)" "unprognostic (2.27e-1)" "unprognostic (3.06e-3)" "unprognostic (4.80e-2)" "unprognostic (1.13e-3)" "validated prognostic favorable (8.63e-4)" "validated prognostic favorable (5.82e-4)" "unprognostic (9.73e-2)" "unprognostic (5.38e-3)" "unprognostic (1.73e-2)" "unprognostic (1.42e-1)" "unprognostic (1.48e-1)" "unprognostic (2.29e-2)" "unprognostic (1.45e-1)" "unprognostic (1.12e-1)" "unprognostic (1.66e-1)" "unprognostic (3.17e-3)" "unprognostic (9.00e-3)" "unprognostic (2.36e-2)" "unprognostic (1.73e-2)" "unprognostic (1.83e-1)" "unprognostic (1.65e-1)" "unprognostic (4.67e-1)" "unprognostic (1.52e-2)" "unprognostic (3.22e-2)" ZNF287 "ZKSCAN13, ZSCAN45" ENSG00000141040 "Zinc finger protein 287" Q9HBT7 17 16546954-16569204 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Corticotrophs: 21.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029290 Uncertain Approved "Golgi apparatus,Basal body" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 42: Non-specific - Unknown function" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" "Golgi apparatus" "Basal body" "HPA029290: " "unprognostic (1.02e-1)" "unprognostic (1.38e-1)" "unprognostic (7.36e-2)" "unprognostic (3.19e-2)" "unprognostic (9.11e-2)" "unprognostic (4.12e-1)" "unprognostic (1.40e-2)" "unprognostic (1.41e-1)" "unprognostic (1.21e-1)" "potential prognostic favorable (2.52e-5)" "unprognostic (2.29e-1)" "unprognostic (2.73e-1)" "unprognostic (1.78e-3)" "unprognostic (3.55e-1)" "unprognostic (5.95e-2)" "unprognostic (4.75e-2)" "unprognostic (2.18e-1)" "potential prognostic unfavorable (8.75e-6)" "unprognostic (3.53e-3)" "unprognostic (6.82e-2)" "unprognostic (1.49e-2)" "unprognostic (2.46e-2)" "unprognostic (9.32e-2)" "unprognostic (5.77e-3)" "unprognostic (2.00e-1)" "unprognostic (1.20e-1)" "unprognostic (2.80e-1)" ZNF292 "bA393I2.3, KIAA0530, ZFP292, Zn-15, Zn-16" ENSG00000188994 "Zinc finger protein 292" O60281 6 87151803-87265943 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Autism spectrum disorder, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 889.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032154, HPA050618" Uncertain Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 31: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 51: Secretory epithelial cells - Mixed function" 3 "Nucleoplasm, Nuclear membrane" "HPA032154: , HPA050618: " "unprognostic (2.29e-1)" "unprognostic (4.68e-2)" "unprognostic (2.26e-2)" "unprognostic (2.15e-2)" "unprognostic (1.09e-1)" "unprognostic (4.83e-2)" "unprognostic (8.86e-2)" "unprognostic (1.08e-2)" "unprognostic (4.09e-2)" "unprognostic (4.87e-3)" "validated prognostic favorable (5.89e-4)" "validated prognostic favorable (7.47e-6)" "unprognostic (1.27e-1)" "unprognostic (2.55e-2)" "unprognostic (1.26e-1)" "unprognostic (1.15e-1)" "unprognostic (5.73e-2)" "unprognostic (6.35e-2)" "unprognostic (1.36e-2)" "unprognostic (7.02e-2)" "unprognostic (4.42e-3)" "unprognostic (4.15e-2)" "unprognostic (2.07e-3)" "unprognostic (3.33e-1)" "unprognostic (2.39e-2)" "unprognostic (4.40e-2)" "unprognostic (8.27e-2)" "unprognostic (2.19e-1)" "unprognostic (3.18e-1)" "unprognostic (1.05e-1)" "unprognostic (2.87e-1)" ZNF296 ZNF342 ENSG00000170684 "Zinc finger protein 296" Q8WUU4 19 45071500-45076478 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 9.4" "Cell type enhanced" "Detected in many" "B-cells: 22.6;Breast lactating cells: 47.1;Breast secretory cells: 35.7;Colonocytes: 27.9;Differentiating spermatogonia: 24.2;Enteric stem cells: 28.5;Enteric transient amplifying cells: 29.2;Enterocytes: 25.8;Esophageal apical cells: 24.8;Esophageal basal cells: 25.8;Esophageal suprabasal cells: 29.9;Goblet cells: 26.0;Paneth cells: 30.9" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 32.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "lymphoma: 19.9" "Breast - Breast glandular cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in single" "HPA046940, HPA049576" Uncertain Approved Nucleoplasm,Centrosome NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 55: Lymphoma - Immune response" "Cluster 20: Non-specific - Transcription regulation" 11 Nucleoplasm Centrosome "HPA046940: , HPA049576: " "potential prognostic favorable (6.37e-5)" "unprognostic (3.56e-1)" "unprognostic (1.80e-1)" "unprognostic (1.21e-1)" "unprognostic (3.02e-1)" "unprognostic (2.93e-1)" "unprognostic (2.74e-1)" "unprognostic (3.89e-3)" "unprognostic (1.29e-1)" "potential prognostic unfavorable (6.19e-4)" "unprognostic (9.35e-2)" "unprognostic (3.59e-1)" "unprognostic (7.73e-3)" "potential prognostic unfavorable (4.57e-4)" "unprognostic (2.04e-1)" "unprognostic (3.73e-3)" "unprognostic (5.92e-2)" "potential prognostic favorable (2.36e-4)" "potential prognostic favorable (9.65e-4)" "unprognostic (1.76e-1)" "unprognostic (1.40e-1)" "unprognostic (1.06e-1)" "unprognostic (5.35e-3)" "unprognostic (8.92e-2)" "unprognostic (2.03e-3)" "unprognostic (2.38e-1)" "unprognostic (2.14e-2)" "unprognostic (1.98e-1)" ZNF3 "A8-51, FLJ20216, HF.12, KOX25, PP838, Zfp113" ENSG00000166526 "Zinc finger protein 3" P17036 7 100064033-100082548 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" HPA003719 Supported Supported Approved Nucleoplasm No No "Cluster 32: Basophils - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 14 Nucleoplasm "HPA003719: " "unprognostic (6.94e-2)" "unprognostic (2.01e-1)" "unprognostic (2.30e-1)" "unprognostic (2.77e-2)" "unprognostic (1.49e-1)" "unprognostic (5.71e-3)" "unprognostic (2.94e-2)" "unprognostic (3.53e-2)" "unprognostic (8.06e-2)" "unprognostic (3.29e-3)" "potential prognostic favorable (1.18e-4)" "unprognostic (1.18e-2)" "unprognostic (1.50e-1)" "unprognostic (1.17e-1)" "unprognostic (3.25e-1)" "unprognostic (3.32e-2)" "unprognostic (4.92e-3)" "unprognostic (2.46e-3)" "unprognostic (8.26e-3)" "unprognostic (3.04e-1)" "potential prognostic favorable (9.11e-4)" "unprognostic (1.84e-2)" "unprognostic (3.24e-2)" "unprognostic (2.45e-2)" "unprognostic (2.63e-1)" "unprognostic (2.25e-1)" "potential prognostic unfavorable (8.57e-4)" "unprognostic (5.28e-2)" "unprognostic (4.98e-2)" "unprognostic (4.10e-3)" "unprognostic (1.37e-2)" ZNF30 "DKFZp686N19164, FLJ20562, KOX28" ENSG00000168661 "Zinc finger protein 30" P17039 19 34926903-34945170 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.5;retina: 14.4" "Cell type enhanced" "Detected in many" "Bergmann glia: 27.2;Cone photoreceptor cells: 45.5;Myonuclei: 26.1;Rod photoreceptor cells: 56.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" HPA030400 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 15: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 79: Photoreceptor cells - Phototransduction" Nucleoplasm Cytosol "HPA030400: " "unprognostic (1.92e-2)" "unprognostic (2.54e-1)" "unprognostic (2.62e-1)" "unprognostic (1.73e-2)" "unprognostic (9.20e-2)" "unprognostic (1.31e-1)" "unprognostic (1.21e-1)" "unprognostic (2.11e-1)" "unprognostic (1.28e-1)" "unprognostic (2.61e-2)" "unprognostic (3.17e-2)" "unprognostic (1.51e-2)" "unprognostic (1.87e-3)" "unprognostic (1.06e-3)" "unprognostic (2.23e-1)" "unprognostic (4.90e-2)" "unprognostic (5.53e-2)" "unprognostic (4.22e-2)" "unprognostic (1.98e-1)" "unprognostic (1.88e-1)" "unprognostic (3.63e-1)" "unprognostic (1.32e-3)" "unprognostic (1.27e-2)" "unprognostic (1.35e-1)" "unprognostic (5.11e-3)" "unprognostic (1.79e-2)" "unprognostic (4.08e-3)" "unprognostic (2.58e-1)" "unprognostic (1.52e-1)" "unprognostic (9.94e-2)" "unprognostic (2.80e-1)" ZNF300 ENSG00000145908 "Zinc finger protein 300" Q96RE9 5 150894392-150904983 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells" "Low region specificity" "Detected in all" "HPA028975, HPA051777" Uncertain Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Nuclear bodies" NA NA "Cluster 65: Brain - Transcription" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 1 Nucleoplasm "Nucleoli, Nucleoli rim, Nuclear bodies" "HPA028975: , HPA051777: " "unprognostic (3.93e-1)" "unprognostic (9.03e-2)" "unprognostic (3.50e-2)" "unprognostic (2.07e-2)" "unprognostic (1.58e-1)" "unprognostic (7.66e-2)" "unprognostic (2.89e-2)" "unprognostic (2.22e-2)" "unprognostic (2.28e-2)" "potential prognostic unfavorable (5.36e-4)" "unprognostic (1.88e-1)" "unprognostic (1.15e-1)" "unprognostic (1.40e-1)" "unprognostic (2.27e-1)" "unprognostic (1.25e-1)" "unprognostic (2.34e-2)" "unprognostic (5.86e-2)" "unprognostic (4.88e-2)" "unprognostic (2.42e-1)" "unprognostic (4.48e-2)" "unprognostic (9.44e-2)" "unprognostic (9.79e-3)" "unprognostic (1.41e-2)" "unprognostic (2.07e-2)" "unprognostic (3.88e-1)" "unprognostic (4.15e-2)" "potential prognostic unfavorable (8.62e-4)" "unprognostic (3.76e-1)" "unprognostic (4.14e-1)" "unprognostic (8.01e-2)" ZNF302 "ZNF135L, ZNF140L, ZNF327" ENSG00000089335 "Zinc finger protein 302" Q9NR11 19 34677639-34686397 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 181.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA045896 Approved Nucleoplasm NA No "Cluster 3: Non-specific - Nuclear processes" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 5 Nucleoplasm "HPA045896: " "unprognostic (2.13e-2)" "unprognostic (1.45e-1)" "unprognostic (3.80e-1)" "unprognostic (4.72e-1)" "unprognostic (4.67e-3)" "unprognostic (1.32e-2)" "unprognostic (2.37e-1)" "unprognostic (3.16e-2)" "unprognostic (2.48e-2)" "unprognostic (3.14e-1)" "unprognostic (8.88e-3)" "unprognostic (4.68e-3)" "unprognostic (4.45e-3)" "unprognostic (6.93e-2)" "unprognostic (2.71e-2)" "unprognostic (3.15e-2)" "unprognostic (6.35e-2)" "unprognostic (1.12e-1)" "unprognostic (2.16e-1)" "unprognostic (6.75e-2)" "unprognostic (1.68e-1)" "unprognostic (5.92e-3)" "unprognostic (8.66e-2)" "unprognostic (2.17e-1)" "unprognostic (1.01e-1)" "unprognostic (3.08e-2)" "unprognostic (2.99e-3)" "unprognostic (1.23e-2)" "unprognostic (9.41e-2)" "unprognostic (3.29e-2)" "unprognostic (5.29e-2)" ZNF304 ENSG00000131845 "Zinc finger protein 304" Q9HCX3 19 57351271-57359898 "Predicted intracellular proteins, Transcription factors" "Angiogenesis, Transcription, Transcription regulation" "Activator, Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050531 Approved Approved "Nuclear speckles,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 35: Neurons - Synaptic function & neurogenesis" "Nuclear speckles" Cytosol "HPA050531: " "unprognostic (3.72e-3)" "unprognostic (4.77e-1)" "unprognostic (1.60e-1)" "unprognostic (4.55e-3)" "unprognostic (1.69e-1)" "unprognostic (4.81e-1)" "unprognostic (2.42e-1)" "unprognostic (8.58e-2)" "unprognostic (1.63e-1)" "unprognostic (1.71e-1)" "potential prognostic favorable (2.20e-9)" "unprognostic (4.47e-3)" "unprognostic (2.17e-2)" "unprognostic (2.08e-1)" "unprognostic (2.34e-1)" "unprognostic (2.24e-1)" "unprognostic (7.77e-2)" "unprognostic (3.04e-1)" "unprognostic (5.54e-2)" "unprognostic (2.81e-1)" "unprognostic (1.06e-1)" "unprognostic (7.96e-3)" "unprognostic (1.32e-1)" "unprognostic (1.13e-1)" "unprognostic (3.86e-1)" "unprognostic (1.68e-1)" "unprognostic (1.63e-2)" "unprognostic (4.35e-2)" "unprognostic (4.20e-2)" "unprognostic (1.62e-1)" "unprognostic (2.13e-1)" ZNF311 ENSG00000197935 "Zinc finger protein 311" Q5JNZ3 6 28994785-29005316 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 2.4" "Cell type enhanced" "Detected in some" "Astrocytes: 2.2;Bergmann glia: 5.5;Ependymal cells: 5.7;Loop of henle epithelial cells: 3.4;Melanocytes: 4.1;Microglia: 3.4;Oligodendrocyte progenitor cells: 2.4;Oligodendrocytes: 2.6;Paneth cells: 3.9;Papillary tip epithelial cells: 3.6;Podocytes: 3.1;Renal collecting duct intercalated cells: 2.1;Renal collecting duct principal cells: 3.6;Renal connecting tubule cells: 2.2" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA050541 Approved NA NA "Cluster 21: Testis - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 34: Ciliated cells - Cilia assembly & function" "HPA050541: " "unprognostic (1.32e-1)" "unprognostic (2.10e-2)" "unprognostic (3.16e-2)" "unprognostic (4.18e-1)" "unprognostic (1.42e-1)" ZNF316 "ENST00000305834, MZF-3" ENSG00000205903 "Zinc finger protein 316" A6NFI3 7 6637318-6658279 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 55.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 49: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 6 "unprognostic (3.83e-2)" "unprognostic (3.45e-1)" "potential prognostic unfavorable (1.63e-4)" "unprognostic (1.35e-2)" "unprognostic (1.26e-1)" "unprognostic (2.72e-1)" "unprognostic (2.64e-1)" "unprognostic (3.65e-1)" "unprognostic (4.92e-2)" "unprognostic (1.11e-3)" "potential prognostic favorable (2.37e-4)" "unprognostic (1.52e-1)" "unprognostic (6.93e-2)" "unprognostic (3.10e-2)" "unprognostic (6.78e-3)" "unprognostic (2.14e-1)" "potential prognostic favorable (9.97e-4)" "unprognostic (5.80e-3)" "unprognostic (9.34e-3)" "unprognostic (5.38e-3)" "unprognostic (9.94e-2)" "unprognostic (2.31e-2)" "unprognostic (2.33e-3)" "unprognostic (1.75e-1)" "unprognostic (1.01e-2)" "unprognostic (6.08e-2)" "unprognostic (1.51e-1)" "unprognostic (3.82e-2)" "unprognostic (1.39e-1)" ZNF317 ENSG00000130803 "Zinc finger protein 317" Q96PQ6 19 9140397-9163424 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Tuft cells: 46.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042075, HPA048625" Approved Enhanced Nucleoplasm NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 23: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 16 Nucleoplasm "HPA042075: , HPA048625: " "unprognostic (1.41e-2)" "unprognostic (3.30e-1)" "unprognostic (2.61e-1)" "unprognostic (7.08e-2)" "unprognostic (1.52e-1)" "unprognostic (1.19e-3)" "unprognostic (4.95e-2)" "unprognostic (2.59e-2)" "unprognostic (1.49e-3)" "unprognostic (5.38e-2)" "unprognostic (1.78e-1)" "unprognostic (6.13e-3)" "unprognostic (1.40e-1)" "unprognostic (1.77e-3)" "unprognostic (2.44e-1)" "unprognostic (1.65e-1)" "unprognostic (2.38e-2)" "unprognostic (2.26e-2)" "unprognostic (7.16e-2)" "potential prognostic favorable (6.75e-4)" "unprognostic (1.16e-1)" "unprognostic (1.03e-1)" "unprognostic (7.76e-2)" "unprognostic (3.05e-1)" "unprognostic (1.00e-1)" "unprognostic (5.79e-2)" "unprognostic (2.52e-2)" "unprognostic (7.13e-2)" "unprognostic (3.60e-2)" "unprognostic (1.92e-1)" "unprognostic (1.82e-1)" ZNF318 "HRIHFB2436, ZFP318" ENSG00000171467 "Zinc finger protein 318" Q5VUA4 6 43307134-43369647 "Predicted intracellular proteins" "Meiosis, Transcription, Transcription regulation" "Activator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 120.5;Late primary spermatocytes: 91.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 2.1" "Lineage enriched" "Detected in single" 4 "B-cells: 2.1" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027022, HPA027031" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 34: B-cells - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 34: Non-specific - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 13 Nucleoplasm Cytosol "HPA027022: , HPA027031: " "unprognostic (3.79e-1)" "unprognostic (2.44e-1)" "unprognostic (1.91e-1)" "unprognostic (1.63e-1)" "unprognostic (8.19e-2)" "unprognostic (1.35e-1)" "unprognostic (5.71e-2)" "unprognostic (1.67e-1)" "unprognostic (1.82e-2)" "unprognostic (4.21e-3)" "unprognostic (1.41e-3)" "unprognostic (1.37e-2)" "unprognostic (3.26e-1)" "unprognostic (1.32e-2)" "unprognostic (3.02e-1)" "unprognostic (2.43e-1)" "unprognostic (3.02e-1)" "unprognostic (5.80e-2)" "unprognostic (5.25e-3)" "unprognostic (1.75e-1)" "unprognostic (2.22e-1)" "unprognostic (9.18e-3)" "unprognostic (6.50e-2)" "unprognostic (7.60e-2)" "unprognostic (4.17e-3)" "unprognostic (3.32e-1)" "unprognostic (3.70e-2)" "unprognostic (4.42e-1)" "unprognostic (4.67e-1)" "unprognostic (3.34e-1)" "unprognostic (2.42e-1)" ZNF319 "KIAA1388, Zfp319" ENSG00000166188 "Zinc finger protein 319" Q9P2F9 16 57994676-58000672 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 21.3;Kupffer cells: 11.3;Neutrophils: 19.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052584 Uncertain Approved Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 24: Neutrophils - Innate immunity signal integration" 19 Nucleoplasm "HPA052584: " "unprognostic (2.60e-1)" "unprognostic (1.29e-1)" "unprognostic (3.15e-1)" "unprognostic (2.87e-3)" "unprognostic (2.91e-1)" "unprognostic (2.30e-2)" "unprognostic (3.13e-1)" "potential prognostic favorable (4.61e-4)" "unprognostic (3.55e-1)" "unprognostic (1.45e-1)" "unprognostic (3.75e-3)" "unprognostic (5.89e-2)" "unprognostic (2.49e-1)" "unprognostic (2.03e-3)" "unprognostic (2.86e-2)" "unprognostic (9.31e-2)" "unprognostic (2.90e-1)" "unprognostic (1.03e-2)" "unprognostic (1.27e-1)" "unprognostic (5.47e-2)" "unprognostic (5.24e-2)" "unprognostic (1.23e-3)" "unprognostic (2.49e-1)" "unprognostic (4.43e-1)" "unprognostic (2.56e-2)" "unprognostic (2.58e-1)" "unprognostic (3.25e-3)" "unprognostic (3.49e-2)" "unprognostic (1.83e-1)" "unprognostic (9.25e-2)" "unprognostic (4.40e-2)" ZNF32 "KOX30, Zfp637, ZNF637" ENSG00000169740 "Zinc finger protein 32" P17041 10 43643860-43648881 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039148, HPA059640" Approved "Nucleoplasm,Nuclear bodies,Cytosol" Yes No "Cluster 3: Non-specific - Nuclear processes" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 10 "Nucleoplasm, Nuclear bodies" Cytosol "HPA039148: , HPA059640: " "unprognostic (1.42e-1)" "potential prognostic unfavorable (2.37e-4)" "unprognostic (1.90e-1)" "unprognostic (1.64e-2)" "unprognostic (1.95e-2)" "unprognostic (1.40e-2)" "unprognostic (1.50e-2)" "unprognostic (2.66e-3)" "unprognostic (4.75e-2)" "unprognostic (1.50e-1)" "unprognostic (1.71e-1)" "unprognostic (1.02e-1)" "unprognostic (8.38e-3)" "unprognostic (4.84e-3)" "unprognostic (1.11e-2)" "unprognostic (4.97e-2)" "unprognostic (1.70e-1)" "unprognostic (1.16e-2)" "unprognostic (1.25e-1)" "unprognostic (2.43e-3)" "unprognostic (2.17e-1)" "potential prognostic favorable (8.42e-4)" "unprognostic (2.03e-1)" "unprognostic (1.00e-1)" "unprognostic (2.14e-1)" "unprognostic (1.27e-1)" "unprognostic (7.85e-3)" "unprognostic (1.11e-1)" "unprognostic (1.27e-2)" "unprognostic (9.97e-2)" "unprognostic (3.67e-1)" ZNF320 "DKFZp686G16228, ZFPL" ENSG00000182986 "Zinc finger protein 320" A2RRD8 19 52860851-52897693 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 68.0;Endometrial luminal cells: 69.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA043696, HPA062474" Uncertain Approved "Nucleoplasm,Cytoplasmic bodies" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 61: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 8 Nucleoplasm "Cytoplasmic bodies" "HPA043696: , HPA062474: " "potential prognostic favorable (7.50e-5)" "unprognostic (1.31e-2)" "unprognostic (1.40e-1)" "unprognostic (6.39e-2)" "unprognostic (9.13e-2)" "unprognostic (6.96e-2)" "unprognostic (1.38e-1)" "unprognostic (2.21e-1)" "unprognostic (1.24e-1)" "unprognostic (1.03e-1)" "potential prognostic favorable (2.55e-5)" "unprognostic (5.94e-3)" "potential prognostic favorable (8.88e-4)" "unprognostic (5.00e-3)" "unprognostic (7.28e-2)" "unprognostic (4.28e-2)" "unprognostic (2.03e-1)" "unprognostic (6.16e-3)" "unprognostic (2.57e-1)" "unprognostic (1.03e-1)" "unprognostic (4.81e-2)" "unprognostic (2.04e-1)" "unprognostic (1.65e-1)" "unprognostic (6.73e-2)" "unprognostic (2.85e-2)" "unprognostic (2.33e-1)" "unprognostic (2.50e-3)" "unprognostic (1.71e-1)" "unprognostic (2.12e-1)" "unprognostic (5.35e-2)" "unprognostic (1.17e-1)" ZNF322 "bA457M11.2, bA457M11.3, HCG12, ZNF322A, ZNF388, ZNF489" ENSG00000181315 "Zinc finger protein 322" Q6U7Q0 6 26634383-26659752 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043161, HPA046692" Approved Supported Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 7: Non-specific - Transcription" Nucleoplasm "Centrosome, Cytosol" "HPA043161: , HPA046692: " "unprognostic (7.58e-3)" "unprognostic (6.57e-3)" "unprognostic (1.30e-1)" "unprognostic (3.11e-1)" "unprognostic (1.37e-1)" "unprognostic (7.71e-2)" "unprognostic (8.27e-2)" "unprognostic (1.09e-1)" "potential prognostic unfavorable (8.77e-5)" "potential prognostic favorable (6.83e-7)" "unprognostic (2.04e-3)" "unprognostic (4.18e-1)" "unprognostic (1.32e-3)" "unprognostic (8.27e-3)" "unprognostic (3.49e-2)" "unprognostic (1.89e-2)" "unprognostic (3.31e-3)" "unprognostic (1.05e-1)" "unprognostic (2.59e-3)" "unprognostic (1.29e-1)" "unprognostic (1.40e-3)" "unprognostic (5.67e-2)" "unprognostic (9.79e-3)" "unprognostic (2.11e-2)" "unprognostic (1.49e-2)" "unprognostic (5.88e-2)" "unprognostic (1.59e-1)" "unprognostic (3.80e-3)" "unprognostic (1.07e-1)" ZNF324 "ZF5128, ZNF324A" ENSG00000083812 "Zinc finger protein 324" O75467 19 58467056-58475436 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" HPA039774 Uncertain Approved "Nucleoplasm,Nuclear membrane,Cytosol" No No "Cluster 21: Neutrophils - Unknown function" "Cluster 2: Non-specific - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 6 "Nucleoplasm, Nuclear membrane, Cytosol" "HPA039774: " "unprognostic (3.77e-2)" "unprognostic (1.01e-1)" "unprognostic (1.28e-1)" "unprognostic (4.14e-2)" "unprognostic (2.25e-1)" "unprognostic (2.92e-2)" "unprognostic (1.66e-2)" "unprognostic (7.10e-3)" "unprognostic (4.48e-3)" "unprognostic (2.14e-1)" "potential prognostic favorable (7.97e-6)" "unprognostic (2.72e-3)" "unprognostic (8.87e-3)" "unprognostic (6.48e-2)" "unprognostic (2.95e-3)" "unprognostic (8.79e-2)" "unprognostic (4.05e-2)" "unprognostic (2.51e-2)" "unprognostic (4.39e-2)" "unprognostic (5.78e-2)" "unprognostic (4.54e-1)" "potential prognostic favorable (2.96e-4)" "unprognostic (1.71e-1)" "unprognostic (1.18e-2)" "unprognostic (4.38e-2)" "unprognostic (1.94e-1)" "unprognostic (2.71e-1)" "unprognostic (2.00e-1)" "unprognostic (1.57e-1)" "unprognostic (2.45e-3)" "unprognostic (7.39e-2)" ZNF324B FLJ45850 ENSG00000249471 "Zinc finger protein 324B" Q6AW86 19 58451611-58457833 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 10.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "NK-cell: 4.1" "Lineage enriched" "Detected in single" 6 "NK-cells: 4.1" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" HPA023400 Uncertain Approved Nucleoli,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 49: Non-specific - Transcription" "Cluster 12: Non-specific - Vasculature" "Cluster 4: Non-specific - Transcription" "Cluster 3: Early primary spermatocytes - Early meiosis" 8 Nucleoli Cytosol "HPA023400: " "unprognostic (2.54e-2)" "unprognostic (2.09e-1)" "unprognostic (1.80e-1)" "unprognostic (2.47e-2)" "unprognostic (3.27e-1)" "unprognostic (2.31e-1)" "unprognostic (4.22e-2)" "unprognostic (1.64e-1)" "unprognostic (7.70e-3)" "unprognostic (8.54e-2)" "unprognostic (8.74e-3)" "unprognostic (1.94e-1)" "unprognostic (1.93e-1)" "unprognostic (4.79e-2)" "unprognostic (1.20e-1)" "unprognostic (1.17e-1)" "unprognostic (4.51e-2)" "unprognostic (6.52e-2)" "unprognostic (9.73e-2)" "unprognostic (5.11e-1)" "unprognostic (2.21e-1)" "unprognostic (2.18e-3)" "unprognostic (2.35e-2)" "unprognostic (6.39e-2)" "unprognostic (3.89e-3)" "unprognostic (1.80e-1)" "unprognostic (1.87e-1)" "unprognostic (7.27e-2)" "unprognostic (4.55e-2)" "unprognostic (7.17e-3)" "unprognostic (2.08e-1)" ZNF326 "FLJ20403, ZAN75, Zfp326, ZIRD" ENSG00000162664 "Zinc finger protein 326" Q5BKZ1 1 89995110-90035533 "Predicted intracellular proteins" "mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 48.7" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 389.2;Rod photoreceptor cells: 551.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028450, HPA028461, HPA028466" Supported Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 55: Non-specific - Transcription" "Cluster 56: Non-specific - Sensory perception" "Cluster 79: Photoreceptor cells - Phototransduction" 65 Nucleoplasm "Golgi apparatus, Vesicles" "HPA028450: , HPA028461: , HPA028466: " "unprognostic (8.05e-2)" "unprognostic (1.52e-1)" "unprognostic (2.13e-3)" "unprognostic (6.59e-3)" "unprognostic (9.44e-2)" "unprognostic (3.51e-2)" "unprognostic (4.06e-2)" "unprognostic (3.50e-2)" "potential prognostic favorable (3.41e-4)" "unprognostic (7.13e-2)" "unprognostic (3.91e-2)" "potential prognostic favorable (6.68e-4)" "unprognostic (8.19e-2)" "unprognostic (2.87e-1)" "unprognostic (7.63e-3)" "unprognostic (1.84e-1)" "unprognostic (5.33e-2)" "unprognostic (6.28e-2)" "unprognostic (4.43e-3)" "unprognostic (6.28e-2)" "unprognostic (1.52e-1)" "unprognostic (8.99e-2)" "unprognostic (9.71e-3)" "unprognostic (5.99e-2)" "potential prognostic favorable (1.30e-4)" "unprognostic (8.97e-2)" "unprognostic (1.39e-1)" "unprognostic (1.49e-2)" "unprognostic (5.08e-2)" "unprognostic (2.14e-2)" "unprognostic (2.61e-1)" ZNF329 FLJ12586 ENSG00000181894 "Zinc finger protein 329" Q86UD4 19 58126248-58155110 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044373, HPA077958" Uncertain Approved Nucleoplasm NA NA "Cluster 41: Basophils - Unknown function" "Cluster 65: Brain - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 21 Nucleoplasm "HPA044373: , HPA077958: " "unprognostic (3.11e-2)" "unprognostic (2.25e-1)" "unprognostic (6.91e-2)" "unprognostic (1.82e-1)" "unprognostic (1.66e-1)" "unprognostic (5.14e-2)" "unprognostic (1.74e-1)" "unprognostic (7.07e-2)" "unprognostic (3.79e-3)" "unprognostic (7.05e-2)" "validated prognostic favorable (9.26e-7)" "validated prognostic favorable (1.91e-4)" "unprognostic (7.77e-3)" "unprognostic (7.64e-3)" "unprognostic (1.22e-1)" "unprognostic (1.42e-1)" "unprognostic (6.32e-3)" "unprognostic (4.61e-1)" "unprognostic (3.10e-1)" "unprognostic (6.01e-2)" "unprognostic (1.85e-1)" "unprognostic (5.59e-3)" "unprognostic (9.32e-2)" "unprognostic (3.70e-2)" "unprognostic (1.92e-2)" "unprognostic (1.48e-1)" "unprognostic (2.66e-3)" "unprognostic (4.94e-2)" "unprognostic (1.02e-1)" "unprognostic (1.99e-2)" "unprognostic (1.19e-1)" ZNF330 "HSA6591, NOA36" ENSG00000109445 "Zinc finger protein 330" Q9Y3S2 4 141220887-141234697 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 160.6;Early spermatids: 241.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Neutrophils, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015705, HPA056325" Uncertain Supported "Nucleoli,Plasma membrane,Primary cilium,Centrosome,Basal body,Cytosol" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 55: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 17: Non-specific - RNA processing" 50 Nucleoli "Plasma membrane, Primary cilium, Centrosome, Basal body, Cytosol" "HPA015705: , HPA056325: " "unprognostic (5.62e-2)" "unprognostic (2.71e-1)" "unprognostic (1.31e-1)" "unprognostic (2.76e-2)" "unprognostic (5.23e-2)" "unprognostic (2.52e-2)" "unprognostic (1.11e-1)" "unprognostic (1.09e-1)" "unprognostic (1.63e-1)" "unprognostic (7.97e-3)" "validated prognostic favorable (1.06e-6)" "validated prognostic favorable (4.77e-4)" "unprognostic (4.58e-2)" "unprognostic (2.16e-2)" "unprognostic (3.92e-2)" "unprognostic (3.22e-2)" "unprognostic (1.23e-2)" "unprognostic (1.43e-1)" "unprognostic (9.14e-2)" "unprognostic (2.18e-1)" "unprognostic (8.97e-2)" "unprognostic (8.69e-2)" "unprognostic (1.12e-1)" "potential prognostic unfavorable (3.92e-5)" "unprognostic (3.56e-2)" "unprognostic (1.39e-2)" "unprognostic (3.83e-3)" "unprognostic (6.97e-2)" "unprognostic (1.42e-1)" "unprognostic (4.00e-3)" "unprognostic (1.63e-2)" ZNF331 "RITA, ZNF361, ZNF463" ENSG00000130844 "Zinc finger protein 331" Q9NQX6 19 53519527-53580269 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 117.5" "Cell type enhanced" "Detected in many" "B-cells: 767.0;cDC: 760.2;Epicardial cells: 2083.1;Innate lymphoid cells: 941.2;Lactotrophs: 951.1;Macrophages: 781.1;Mast cells: 1137.2;monocytes: 1175.1;NK-cells: 722.3;Ovarian stromal cells: 672.2;pDCs: 902.6;Somatotrophs: 1560.8;T-cells: 830.4;Vascular smooth muscle cells: 682.1" "Group enriched" "Detected in all" 4 "central nervous system macrophage: 132.9;leukocyte: 167.2;vascular associated smooth muscle cell: 519.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063157 Approved Nucleoplasm NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 103: Non-specific - Basic cellular processes" 5 Nucleoplasm "HPA063157: " "unprognostic (3.25e-2)" "unprognostic (2.33e-1)" "unprognostic (2.86e-1)" "unprognostic (4.59e-3)" "unprognostic (1.21e-1)" "unprognostic (6.94e-2)" "unprognostic (2.39e-1)" "unprognostic (2.00e-1)" "unprognostic (6.36e-2)" "unprognostic (3.69e-2)" "validated prognostic favorable (3.96e-4)" "validated prognostic favorable (4.21e-4)" "potential prognostic favorable (6.51e-4)" "unprognostic (1.70e-2)" "unprognostic (1.56e-1)" "unprognostic (1.22e-1)" "unprognostic (2.11e-1)" "unprognostic (1.29e-3)" "unprognostic (2.44e-1)" "unprognostic (1.85e-2)" "unprognostic (2.91e-1)" "unprognostic (1.35e-2)" "unprognostic (3.04e-2)" "unprognostic (4.69e-1)" "unprognostic (2.69e-1)" "unprognostic (1.63e-3)" "unprognostic (7.66e-3)" "unprognostic (1.10e-3)" "unprognostic (1.21e-1)" "potential prognostic unfavorable (2.82e-4)" "unprognostic (3.36e-2)" ZNF333 KIAA1806 ENSG00000160961 "Zinc finger protein 333" Q96JL9 19 14689801-14733746 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 54.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "HPA043973, HPA054680, HPA077662" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 7 Nucleoplasm Cytosol "HPA043973: , HPA054680: , HPA077662: " "unprognostic (4.04e-2)" "unprognostic (2.50e-1)" "unprognostic (2.65e-1)" "unprognostic (7.18e-3)" "unprognostic (1.01e-1)" "unprognostic (2.26e-1)" "unprognostic (1.91e-1)" "unprognostic (8.48e-2)" "unprognostic (2.24e-2)" "unprognostic (1.54e-2)" "unprognostic (2.20e-2)" "unprognostic (1.46e-1)" "unprognostic (6.43e-2)" "unprognostic (3.82e-3)" "unprognostic (2.32e-1)" "unprognostic (1.23e-1)" "unprognostic (6.74e-3)" "unprognostic (1.98e-1)" "unprognostic (1.58e-2)" "unprognostic (2.79e-2)" "unprognostic (1.15e-1)" "unprognostic (1.65e-2)" "unprognostic (6.13e-3)" "unprognostic (2.40e-1)" "unprognostic (7.77e-2)" "unprognostic (4.77e-2)" "unprognostic (8.86e-3)" "unprognostic (2.35e-1)" "unprognostic (7.88e-2)" "unprognostic (8.48e-2)" "unprognostic (6.60e-2)" ZNF334 bA179N14.1 ENSG00000198185 "Zinc finger protein 334" Q9HCZ1 20 46499630-46513559 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 50.0;Bergmann glia: 60.5;Breast lactating cells: 65.3;Corticotrophs: 52.9;Pituicytes/FSCs: 59.3;Pituitary stem cells: 61.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.0" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "testis cancer: 20.0" "Low region specificity" "Detected in all" HPA050022 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 21: Testis - Mixed function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 2 Nucleoplasm Cytosol "HPA050022: " "unprognostic (2.05e-2)" "unprognostic (4.53e-2)" "unprognostic (1.48e-3)" "unprognostic (6.41e-3)" "unprognostic (3.54e-1)" "unprognostic (1.04e-1)" "unprognostic (1.24e-1)" "unprognostic (2.17e-1)" "unprognostic (2.39e-2)" "unprognostic (3.78e-2)" "unprognostic (5.13e-2)" "potential prognostic favorable (2.76e-5)" "unprognostic (1.62e-3)" "unprognostic (5.72e-2)" "unprognostic (3.51e-1)" "unprognostic (4.20e-1)" "unprognostic (1.92e-1)" "unprognostic (6.31e-2)" "unprognostic (1.99e-1)" "unprognostic (1.31e-1)" "unprognostic (1.15e-1)" "unprognostic (3.10e-2)" "unprognostic (2.33e-2)" "unprognostic (1.70e-1)" "unprognostic (1.47e-2)" "unprognostic (2.03e-3)" "unprognostic (2.30e-1)" "unprognostic (3.73e-2)" "unprognostic (5.98e-2)" ZNF335 "bA465L10.2, NIF-1" ENSG00000198026 "Zinc finger protein 335" Q9H4Z2 20 45948660-45972203 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant, Intellectual disability, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 122.2;Late spermatids: 117.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063999, HPA071230" Enhanced Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 65: Non-specific - Cell growth & division" 4 Nucleoplasm "HPA063999: , HPA071230: " "unprognostic (2.17e-2)" "unprognostic (7.80e-2)" "unprognostic (3.85e-2)" "unprognostic (1.59e-1)" "unprognostic (5.52e-2)" "unprognostic (8.48e-2)" "unprognostic (3.79e-2)" "unprognostic (1.48e-1)" "potential prognostic favorable (3.51e-4)" "unprognostic (3.01e-1)" "unprognostic (8.54e-3)" "unprognostic (9.56e-2)" "unprognostic (1.88e-2)" "potential prognostic unfavorable (1.91e-5)" "unprognostic (5.88e-2)" "unprognostic (7.48e-2)" "unprognostic (1.53e-3)" "unprognostic (3.09e-1)" "unprognostic (7.16e-2)" "unprognostic (3.27e-2)" "unprognostic (1.04e-1)" "unprognostic (7.39e-3)" "potential prognostic unfavorable (8.27e-4)" "unprognostic (5.24e-3)" "unprognostic (1.25e-1)" "unprognostic (1.79e-3)" "unprognostic (3.73e-2)" "unprognostic (2.25e-1)" "unprognostic (1.58e-1)" "unprognostic (3.12e-1)" "unprognostic (7.12e-2)" ZNF337 dJ694B14.1 ENSG00000130684 "Zinc finger protein 337" Q9Y3M9 20 25673195-25696853 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 72.1" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA044303, HPA064219" Approved Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 7: Non-specific - Transcription" 8 "Plasma membrane" "Nuclear speckles" "HPA044303: , HPA064219: " "unprognostic (3.21e-3)" "unprognostic (3.87e-2)" "unprognostic (2.49e-2)" "unprognostic (1.81e-2)" "unprognostic (1.31e-1)" "unprognostic (2.98e-1)" "unprognostic (2.29e-1)" "unprognostic (1.98e-2)" "unprognostic (4.84e-2)" "unprognostic (1.68e-1)" "potential prognostic unfavorable (2.54e-4)" "unprognostic (6.48e-3)" "unprognostic (9.03e-2)" "potential prognostic unfavorable (2.86e-5)" "unprognostic (1.69e-1)" "unprognostic (2.54e-2)" "unprognostic (2.45e-3)" "unprognostic (1.08e-1)" "unprognostic (2.00e-1)" "unprognostic (1.01e-2)" "unprognostic (1.43e-2)" "unprognostic (5.10e-3)" "unprognostic (1.20e-2)" "potential prognostic unfavorable (7.88e-4)" "unprognostic (5.12e-3)" "potential prognostic favorable (6.65e-4)" "unprognostic (4.82e-2)" "unprognostic (4.10e-2)" "unprognostic (3.63e-2)" "unprognostic (2.44e-2)" "unprognostic (1.31e-2)" ZNF33A "FLJ23404, KIAA0065, KOX31, KOX5, ZNF11A, ZNF33, ZZAPK" ENSG00000189180 "Zinc finger protein 33A" Q06730 10 38010650-38065088 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 384.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells" "HPA005538, HPA056638" Approved Approved "Nucleoli fibrillar center,Endoplasmic reticulum,Vesicles" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 52: Non-specific - Mitochondria" "Cluster 24: Neutrophils - Innate immunity signal integration" 2 "Nucleoli fibrillar center, Endoplasmic reticulum" Vesicles "HPA005538: , HPA056638: " "unprognostic (1.04e-3)" "unprognostic (7.53e-2)" "unprognostic (1.85e-1)" "unprognostic (2.46e-1)" "potential prognostic unfavorable (9.77e-5)" "unprognostic (4.83e-2)" "unprognostic (2.75e-2)" "unprognostic (1.42e-3)" "unprognostic (1.90e-2)" "unprognostic (1.82e-3)" "potential prognostic favorable (2.75e-5)" "unprognostic (1.89e-2)" "unprognostic (1.77e-1)" "potential prognostic unfavorable (7.22e-4)" "unprognostic (2.86e-2)" "unprognostic (5.58e-2)" "unprognostic (1.13e-1)" "unprognostic (1.51e-1)" "unprognostic (2.13e-1)" "unprognostic (2.51e-1)" "potential prognostic unfavorable (2.29e-4)" "unprognostic (1.30e-1)" "unprognostic (7.46e-2)" "unprognostic (1.64e-1)" "unprognostic (4.77e-2)" "unprognostic (8.37e-2)" "unprognostic (1.92e-2)" "unprognostic (2.27e-1)" "unprognostic (4.77e-2)" "unprognostic (9.28e-2)" "unprognostic (1.93e-1)" ZNF33B "KOX2, KOX31, ZNF11B" ENSG00000196693 "Zinc finger protein 33B" Q06732 10 42574185-42638570 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "HPA005538, HPA056638" Approved Approved "Nucleoli fibrillar center,Endoplasmic reticulum,Vesicles" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 60: Stomach - Digestion" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 52: Non-specific - Mitochondria" "Cluster 7: Non-specific - Transcription" 4 "Nucleoli fibrillar center, Endoplasmic reticulum" Vesicles "HPA005538: , HPA056638: " "unprognostic (1.34e-1)" "unprognostic (1.27e-2)" "unprognostic (6.75e-2)" "unprognostic (1.01e-3)" "unprognostic (8.46e-3)" "unprognostic (1.22e-1)" "unprognostic (1.84e-2)" "potential prognostic favorable (2.13e-4)" "unprognostic (4.20e-2)" "unprognostic (3.22e-2)" "validated prognostic favorable (1.49e-8)" "validated prognostic favorable (2.77e-5)" "unprognostic (6.95e-2)" "unprognostic (1.89e-2)" "unprognostic (7.38e-2)" "unprognostic (9.84e-3)" "unprognostic (9.47e-2)" "unprognostic (2.01e-2)" "unprognostic (8.30e-2)" "unprognostic (1.38e-1)" "unprognostic (5.48e-2)" "unprognostic (2.77e-1)" "unprognostic (2.22e-1)" "unprognostic (6.03e-2)" "unprognostic (6.24e-3)" "unprognostic (2.84e-1)" "unprognostic (1.36e-1)" "unprognostic (1.14e-1)" "unprognostic (6.74e-2)" "unprognostic (2.02e-2)" "unprognostic (1.77e-1)" ZNF34 KOX32 ENSG00000196378 "Zinc finger protein 34" Q8IZ26 8 144772224-144787345 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 33.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053925, HPA060755, HPA066805" Uncertain Enhanced Nucleoplasm,Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 64: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 40: Non-specific - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 8 Nucleoplasm Cytosol "HPA053925: , HPA060755: , HPA066805: " "unprognostic (7.61e-2)" "unprognostic (1.03e-1)" "unprognostic (2.08e-1)" "unprognostic (3.02e-3)" "unprognostic (9.66e-3)" "unprognostic (2.35e-1)" "unprognostic (6.52e-2)" "unprognostic (2.65e-3)" "unprognostic (4.81e-2)" "unprognostic (5.26e-2)" "unprognostic (8.93e-2)" "unprognostic (1.44e-3)" "unprognostic (2.81e-1)" "unprognostic (5.27e-2)" "unprognostic (1.00e-1)" "unprognostic (1.49e-1)" "unprognostic (6.83e-2)" "unprognostic (5.30e-2)" "unprognostic (4.23e-1)" "unprognostic (6.06e-2)" "unprognostic (9.78e-2)" "unprognostic (2.15e-2)" "unprognostic (4.44e-2)" "unprognostic (4.96e-2)" "unprognostic (3.84e-1)" "unprognostic (2.28e-1)" "unprognostic (6.25e-2)" "unprognostic (8.04e-3)" "unprognostic (7.84e-2)" "unprognostic (1.13e-1)" "unprognostic (2.39e-1)" ZNF341 dJ553F4.3 ENSG00000131061 "Zinc finger protein 341" Q9BYN7 20 33731657-33792269 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Myonuclei: 31.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023240, HPA024607, HPA067108" Uncertain Approved "Nucleoplasm,Nuclear bodies,Vesicles" Yes No "Cluster 2: Dendritic cells - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 53: Neurons - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 9 "Nucleoplasm, Vesicles" "Nuclear bodies" "HPA023240: , HPA024607: , HPA067108: " "unprognostic (1.87e-2)" "unprognostic (1.82e-3)" "unprognostic (1.60e-1)" "unprognostic (2.76e-2)" "unprognostic (1.59e-1)" "unprognostic (2.12e-1)" "unprognostic (1.21e-1)" "unprognostic (1.34e-1)" "unprognostic (4.42e-2)" "unprognostic (2.31e-3)" "unprognostic (1.43e-1)" "unprognostic (2.91e-1)" "potential prognostic unfavorable (2.02e-6)" "unprognostic (2.06e-1)" "unprognostic (1.24e-2)" "unprognostic (7.51e-3)" "unprognostic (8.50e-2)" "unprognostic (3.06e-1)" "unprognostic (1.32e-1)" "unprognostic (4.92e-2)" "unprognostic (2.46e-1)" "unprognostic (1.13e-2)" "unprognostic (2.11e-1)" "unprognostic (8.40e-3)" "unprognostic (3.01e-2)" "unprognostic (7.67e-2)" "unprognostic (1.15e-1)" "unprognostic (3.96e-1)" "unprognostic (3.13e-1)" "unprognostic (9.78e-2)" ZNF343 MGC10715 ENSG00000088876 "Zinc finger protein 343" Q6P1L6 20 2481817-2524702 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 10.1;Bergmann glia: 12.7;Brain excitatory neurons: 16.6;Brain inhibitory neurons: 17.6;Choroid plexus epithelial cells: 14.4;Oligodendrocyte progenitor cells: 19.6;Oligodendrocytes: 14.4;Other brain neurons: 15.4;Tuft cells: 11.5;Vascular endothelial cells: 8.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pancreas - Endothelial cells" "HPA030587, HPA052438" Approved Approved Nucleoplasm NA NA "Cluster 18: Non-specific - Translation" "Cluster 22: Epididymis - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 35: Neurons - Synaptic function & neurogenesis" 19 Nucleoplasm "HPA030587: , HPA052438: " "unprognostic (2.18e-2)" "unprognostic (1.60e-2)" "unprognostic (2.21e-3)" "unprognostic (5.05e-2)" "unprognostic (1.05e-1)" "unprognostic (4.02e-2)" "unprognostic (3.36e-1)" "unprognostic (3.80e-1)" "unprognostic (1.51e-1)" "unprognostic (3.46e-2)" "unprognostic (7.20e-2)" "unprognostic (1.71e-2)" "unprognostic (2.46e-1)" "potential prognostic unfavorable (1.00e-4)" "unprognostic (2.00e-2)" "unprognostic (1.12e-1)" "unprognostic (3.61e-2)" "unprognostic (1.27e-1)" "unprognostic (3.43e-1)" "unprognostic (1.14e-1)" "unprognostic (1.27e-1)" "unprognostic (1.30e-1)" "unprognostic (4.57e-2)" "unprognostic (1.26e-1)" "unprognostic (1.37e-2)" "unprognostic (2.07e-1)" "unprognostic (1.26e-1)" "unprognostic (1.51e-1)" "unprognostic (4.91e-1)" "unprognostic (2.88e-2)" "unprognostic (2.11e-2)" ZNF345 HZF10 ENSG00000251247 "Zinc finger protein 345" Q14585 19 36850361-36913029 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 54.6;Bergmann glia: 48.7;Brain inhibitory neurons: 37.9;Choroid plexus epithelial cells: 71.4;Distal convoluted tubule cells: 68.2;Early spermatids: 171.9;Ependymal cells: 46.3;Late spermatids: 261.8;Loop of henle epithelial cells: 45.6;Oligodendrocyte progenitor cells: 54.0;Oligodendrocytes: 55.5;Other brain neurons: 35.2;Podocytes: 61.2;Renal collecting duct intercalated cells: 37.6;Renal collecting duct principal cells: 35.3;Renal connecting tubule cells: 48.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Testis - Late spermatids" "Low region specificity" "Detected in all" HPA025816 Uncertain NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 39: Testis - Nuclear processes" "Cluster 9: Non-specific - Receptor signaling" "Cluster 4: Non-specific - Transcription" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 4 "HPA025816: " "unprognostic (2.62e-2)" "unprognostic (9.67e-2)" "unprognostic (1.96e-1)" "unprognostic (2.85e-1)" "unprognostic (1.70e-1)" "unprognostic (1.44e-3)" "unprognostic (3.13e-1)" "unprognostic (2.54e-2)" "unprognostic (2.60e-3)" "unprognostic (2.45e-1)" "unprognostic (1.46e-1)" "unprognostic (1.01e-2)" "unprognostic (2.70e-2)" "unprognostic (3.35e-2)" "unprognostic (7.02e-3)" "unprognostic (1.38e-3)" "unprognostic (3.50e-1)" "unprognostic (3.59e-2)" "unprognostic (2.57e-2)" "unprognostic (3.46e-1)" "unprognostic (3.07e-2)" "unprognostic (6.92e-3)" "unprognostic (1.84e-2)" "unprognostic (7.02e-2)" "potential prognostic favorable (9.23e-5)" "unprognostic (5.46e-3)" "unprognostic (1.87e-3)" "unprognostic (9.49e-2)" "unprognostic (6.34e-2)" "unprognostic (1.23e-1)" "unprognostic (3.54e-2)" ZNF346 "JAZ, Zfp346" ENSG00000113761 "Zinc finger protein 346" Q9UL40 5 177022696-177081189 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018485 Approved Supported Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 65: Brain - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 33 Nucleoplasm "HPA018485: " "unprognostic (1.64e-3)" "unprognostic (4.47e-2)" "unprognostic (9.74e-2)" "unprognostic (1.40e-1)" "unprognostic (9.83e-3)" "unprognostic (2.17e-2)" "unprognostic (3.42e-1)" "unprognostic (1.54e-2)" "unprognostic (2.82e-1)" "unprognostic (1.76e-2)" "potential prognostic favorable (2.43e-6)" "unprognostic (4.85e-3)" "unprognostic (6.72e-2)" "potential prognostic unfavorable (3.84e-8)" "unprognostic (2.90e-2)" "unprognostic (1.32e-1)" "unprognostic (5.63e-2)" "unprognostic (3.51e-1)" "unprognostic (1.73e-1)" "unprognostic (7.02e-2)" "unprognostic (1.71e-1)" "potential prognostic favorable (4.60e-4)" "unprognostic (1.67e-3)" "unprognostic (2.26e-2)" "unprognostic (1.82e-2)" "unprognostic (5.07e-2)" "unprognostic (4.60e-2)" "unprognostic (1.33e-1)" "unprognostic (9.57e-2)" "unprognostic (1.32e-2)" "unprognostic (8.54e-2)" ZNF347 ZNF1111 ENSG00000197937 "Zinc finger protein 347" Q96SE7 19 53124072-53159075 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" HPA023448 Uncertain Approved Microtubules NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 40: Non-specific - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" Microtubules "HPA023448: " "unprognostic (4.52e-3)" "unprognostic (2.00e-2)" "unprognostic (2.69e-1)" "unprognostic (1.11e-3)" "unprognostic (1.67e-1)" "unprognostic (3.87e-3)" "unprognostic (3.41e-1)" "unprognostic (3.91e-2)" "potential prognostic favorable (6.13e-5)" "unprognostic (1.03e-2)" "unprognostic (1.25e-1)" "unprognostic (1.25e-3)" "unprognostic (2.78e-2)" "potential prognostic unfavorable (4.24e-4)" "unprognostic (3.26e-2)" "unprognostic (3.73e-2)" "unprognostic (4.06e-3)" "unprognostic (1.05e-1)" "unprognostic (9.15e-2)" "unprognostic (1.25e-1)" "unprognostic (2.75e-3)" "unprognostic (9.26e-2)" "unprognostic (1.00e-1)" "unprognostic (6.17e-2)" "unprognostic (2.62e-1)" "unprognostic (1.35e-2)" "unprognostic (1.31e-3)" "unprognostic (1.30e-1)" "unprognostic (1.52e-1)" "unprognostic (7.58e-2)" "unprognostic (1.41e-1)" ZNF35 "HF.10, HF10, Zfp105" ENSG00000169981 "Zinc finger protein 35" P13682 3 44648732-44660791 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 11.5;Bergmann glia: 12.8;Brain excitatory neurons: 10.9;Brain inhibitory neurons: 10.7;Distal convoluted tubule cells: 10.7;Ependymal cells: 10.5;Late primary spermatocytes: 11.6;Oligodendrocyte progenitor cells: 12.5;Oligodendrocytes: 12.4;Other brain neurons: 12.9;Tuft cells: 11.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051859, HPA054738" Uncertain Approved Nucleoplasm NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 67: Testis - Mixed function" "Cluster 25: Non-specific - Transcription" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 102: Non-specific - Mixed function" 26 Nucleoplasm "HPA051859: , HPA054738: " "unprognostic (2.13e-1)" "unprognostic (1.54e-1)" "unprognostic (2.39e-2)" "unprognostic (7.28e-2)" "unprognostic (1.66e-2)" "unprognostic (9.08e-2)" "unprognostic (1.73e-2)" "unprognostic (1.17e-2)" "unprognostic (6.80e-2)" "unprognostic (2.88e-2)" "potential prognostic favorable (3.98e-4)" "unprognostic (8.87e-3)" "unprognostic (1.36e-1)" "unprognostic (1.19e-1)" "unprognostic (1.51e-1)" "unprognostic (1.58e-2)" "unprognostic (2.15e-1)" "unprognostic (2.43e-1)" "unprognostic (2.74e-1)" "unprognostic (8.55e-2)" "unprognostic (2.15e-1)" "unprognostic (1.06e-1)" "unprognostic (2.12e-2)" "unprognostic (7.04e-2)" "unprognostic (2.52e-2)" "unprognostic (2.10e-2)" "unprognostic (9.60e-2)" "unprognostic (1.72e-1)" "unprognostic (2.57e-2)" "unprognostic (2.62e-1)" ZNF350 "ZBRK1, ZFQR" ENSG00000256683 "Zinc finger protein 350" Q9GZX5 19 51964340-51986856 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 49.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "prostate cancer: 31.5" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" HPA001521 Uncertain Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 60: Prostate cancer - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 7 Nucleoplasm "Nuclear bodies" "HPA001521: " "unprognostic (7.65e-3)" "unprognostic (3.96e-3)" "unprognostic (6.86e-2)" "unprognostic (3.97e-2)" "unprognostic (9.98e-2)" "unprognostic (1.43e-1)" "unprognostic (2.75e-1)" "unprognostic (1.50e-1)" "unprognostic (1.72e-2)" "unprognostic (2.24e-1)" "validated prognostic favorable (1.26e-4)" "validated prognostic favorable (3.76e-5)" "unprognostic (2.61e-2)" "unprognostic (1.33e-2)" "unprognostic (3.97e-2)" "unprognostic (2.09e-2)" "unprognostic (1.69e-1)" "unprognostic (5.91e-2)" "unprognostic (2.60e-2)" "unprognostic (1.41e-1)" "unprognostic (4.55e-1)" "unprognostic (5.77e-2)" "unprognostic (1.01e-1)" "unprognostic (1.09e-2)" "unprognostic (5.44e-2)" "unprognostic (6.87e-2)" "unprognostic (5.31e-3)" "unprognostic (9.64e-2)" "unprognostic (4.56e-2)" "unprognostic (1.57e-1)" "unprognostic (2.43e-1)" ZNF354A "EZNF, HKL1, KID-1, KID1, TCF17" ENSG00000169131 "Zinc finger protein 354A" O60765 5 178711512-178730659 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bergmann glia: 23.8;Microglia: 27.0;Proximal tubule cells: 23.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052043 Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 7 "Nucleoplasm, Nucleoli" Cytosol "HPA052043: " "unprognostic (4.98e-2)" "unprognostic (1.06e-1)" "unprognostic (1.91e-1)" "unprognostic (1.36e-1)" "unprognostic (2.96e-2)" "unprognostic (5.00e-2)" "unprognostic (4.32e-2)" "unprognostic (6.94e-2)" "unprognostic (9.15e-2)" "potential prognostic unfavorable (2.98e-4)" "unprognostic (2.41e-1)" "unprognostic (6.05e-2)" "unprognostic (1.72e-2)" "unprognostic (2.70e-2)" "unprognostic (4.70e-2)" "unprognostic (1.31e-1)" "unprognostic (2.02e-1)" "unprognostic (1.96e-2)" "unprognostic (1.13e-1)" "unprognostic (1.80e-1)" "unprognostic (3.33e-2)" "unprognostic (7.28e-2)" "unprognostic (3.70e-3)" "unprognostic (1.32e-1)" "unprognostic (8.09e-2)" "unprognostic (6.36e-2)" "unprognostic (8.77e-2)" "unprognostic (1.63e-1)" "unprognostic (2.36e-1)" "unprognostic (5.86e-3)" "unprognostic (9.45e-2)" ZNF354B "FLJ25008, KID2" ENSG00000178338 "Zinc finger protein 354B" Q96LW1 5 178859953-178888122 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 43.7;Syncytiotrophoblasts: 66.7" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Breast Invasive Carcinoma (TCGA): 75.7;Ovary Serous Cystadenocarcinoma (TCGA): 84.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029056 Approved Approved Nucleoplasm NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 3 Nucleoplasm "HPA029056: " "unprognostic (8.78e-2)" "unprognostic (4.19e-1)" "unprognostic (7.24e-2)" "unprognostic (2.62e-2)" "unprognostic (6.94e-2)" "unprognostic (5.05e-2)" "unprognostic (2.59e-1)" "unprognostic (2.91e-2)" "unprognostic (7.60e-2)" "unprognostic (6.10e-2)" "unprognostic (3.53e-2)" "unprognostic (3.30e-2)" "unprognostic (1.43e-1)" "unprognostic (1.92e-2)" "unprognostic (1.68e-1)" "unprognostic (3.85e-2)" "unprognostic (1.92e-1)" "unprognostic (2.98e-1)" "unprognostic (1.53e-1)" "unprognostic (7.89e-2)" "unprognostic (1.90e-1)" "unprognostic (2.41e-2)" "potential prognostic unfavorable (5.28e-4)" "unprognostic (8.26e-2)" "unprognostic (2.81e-3)" "unprognostic (1.19e-1)" "unprognostic (8.88e-3)" "unprognostic (1.49e-1)" "unprognostic (5.85e-2)" "unprognostic (1.80e-2)" "unprognostic (2.14e-1)" ZNF354C KID3 ENSG00000177932 "Zinc finger protein 354C" Q86Y25 5 179060373-179083977 "Predicted intracellular proteins, Transcription factors" "Angiogenesis, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 36.1;Cardiomyocytes: 30.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030904, HPA068570" Uncertain Supported Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 1 Nucleoplasm "HPA030904: , HPA068570: " "unprognostic (5.63e-2)" "unprognostic (1.83e-1)" "unprognostic (8.41e-2)" "unprognostic (1.33e-1)" "unprognostic (2.38e-1)" "unprognostic (4.58e-1)" "potential prognostic favorable (1.21e-4)" "unprognostic (9.04e-3)" "unprognostic (8.83e-2)" "unprognostic (6.68e-3)" "unprognostic (6.96e-2)" "unprognostic (1.60e-2)" "unprognostic (1.63e-1)" "unprognostic (5.90e-2)" "unprognostic (3.69e-2)" "unprognostic (7.19e-2)" "unprognostic (4.07e-1)" "unprognostic (1.11e-1)" "unprognostic (2.89e-1)" "unprognostic (2.97e-2)" "unprognostic (1.17e-1)" "unprognostic (3.16e-2)" "unprognostic (4.21e-3)" ZNF358 "FLJ10390, ZFEND" ENSG00000198816 "Zinc finger protein 358" Q9NW07 19 7515292-7521025 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030887, HPA063624" Approved Approved Nucleoplasm NA NA "Cluster 41: Basophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 23: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" Nucleoplasm "HPA030887: , HPA063624: " "unprognostic (6.10e-2)" "unprognostic (7.13e-2)" "unprognostic (2.44e-1)" "unprognostic (9.74e-3)" "unprognostic (7.90e-2)" "unprognostic (1.00e-1)" "unprognostic (1.31e-1)" "unprognostic (3.14e-1)" "unprognostic (2.28e-1)" "unprognostic (1.02e-1)" "unprognostic (3.43e-2)" "unprognostic (6.93e-2)" "unprognostic (4.05e-2)" "unprognostic (1.87e-2)" "unprognostic (2.66e-1)" "unprognostic (7.00e-2)" "unprognostic (3.53e-2)" "unprognostic (2.85e-2)" "unprognostic (1.04e-1)" "unprognostic (2.11e-2)" "unprognostic (1.51e-1)" "unprognostic (2.50e-3)" "unprognostic (2.27e-1)" "unprognostic (1.54e-1)" "unprognostic (1.33e-1)" "unprognostic (2.11e-2)" "unprognostic (1.41e-1)" "unprognostic (8.16e-2)" "unprognostic (9.94e-2)" "unprognostic (7.96e-2)" "unprognostic (2.04e-2)" ZNF362 "FLJ25476, lin-29, RN" ENSG00000160094 "Zinc finger protein 362" Q5T0B9 1 33256492-33300719 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059239 Uncertain Approved Nucleoplasm,Nucleoli NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 37: Non-specific - mRNA processing" "Cluster 7: Non-specific - Transcription" 1 Nucleoplasm Nucleoli "HPA059239: " "unprognostic (1.14e-2)" "unprognostic (6.03e-2)" "unprognostic (4.72e-2)" "unprognostic (2.71e-2)" "unprognostic (2.03e-1)" "unprognostic (8.51e-2)" "unprognostic (8.89e-2)" "potential prognostic favorable (6.28e-4)" "unprognostic (3.55e-2)" "unprognostic (7.21e-2)" "unprognostic (1.25e-3)" "potential prognostic favorable (5.85e-4)" "unprognostic (3.54e-3)" "unprognostic (3.93e-3)" "unprognostic (3.48e-2)" "unprognostic (9.96e-3)" "unprognostic (4.32e-2)" "unprognostic (9.18e-2)" "unprognostic (9.45e-2)" "unprognostic (2.68e-1)" "unprognostic (1.59e-2)" "unprognostic (4.72e-2)" "unprognostic (1.03e-1)" "unprognostic (3.51e-1)" "unprognostic (1.07e-1)" "unprognostic (2.46e-2)" "unprognostic (3.23e-1)" "unprognostic (1.06e-1)" "unprognostic (8.79e-2)" "unprognostic (3.15e-1)" "unprognostic (3.04e-1)" ZNF365 "KIAA0844, Su48, UAN" ENSG00000138311 "Zinc finger protein 365" Q70YC5 10 62374192-62480288 "Predicted intracellular proteins" Neurogenesis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 33.5;esophagus: 9.6" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 3.0;Papillary tip epithelial cells: 19.9;Podocytes: 5.7;Proximal tubule cells: 34.3;Renal collecting duct principal cells: 3.5;Renal connecting tubule cells: 13.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 4.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "gdT-cell: 2.4;memory CD4 T-cell: 2.2;memory CD8 T-cell: 2.7;naive CD8 T-cell: 2.7;NK-cell: 6.4;T-reg: 5.9" "Group enriched" "Detected in many" 62 "NK-cells: 6.4;T-cells: 5.9" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal medulla cells, Breast - Breast myoepithelial cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052446 Supported Approved "Vesicles,Centriolar satellite,Centrosome" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 88: Proximal tubular cells - Transmembrane transport" 3 "Centriolar satellite, Centrosome" Vesicles "HPA052446: " "unprognostic (9.95e-2)" "unprognostic (7.63e-2)" "unprognostic (5.33e-2)" "unprognostic (1.53e-1)" "unprognostic (1.99e-3)" "unprognostic (8.34e-3)" "unprognostic (6.98e-2)" "unprognostic (4.76e-2)" "unprognostic (1.23e-1)" "unprognostic (1.34e-2)" "unprognostic (1.50e-3)" "unprognostic (5.61e-2)" ZNF366 FLJ39796 ENSG00000178175 "Zinc finger protein 366" Q8N895 5 72439903-72507410 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 5 "cDC: 84.8;Cone photoreceptor cells: 153.2;Vascular endothelial cells: 99.6" "Cell type enriched" "Detected in many" 17 "endothelial cell: 348.7" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 5.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "myeloid DC: 10.3" "Lineage enriched" "Detected in many" 9 "dendritic cells: 10.3" "Not detected" "Not detected" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Minor Salivary Gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA023128, HPA023526" Uncertain Supported Nucleoplasm NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 24 Nucleoplasm "HPA023128: , HPA023526: " "unprognostic (4.18e-1)" "unprognostic (1.20e-2)" "unprognostic (1.03e-1)" "unprognostic (5.90e-2)" "unprognostic (1.28e-1)" "unprognostic (9.82e-2)" "validated prognostic favorable (7.97e-10)" "validated prognostic favorable (5.99e-4)" "unprognostic (4.41e-3)" "unprognostic (1.63e-1)" "unprognostic (3.63e-1)" "unprognostic (2.65e-2)" "unprognostic (4.47e-2)" "unprognostic (1.30e-1)" "unprognostic (1.31e-1)" "unprognostic (6.31e-2)" "unprognostic (3.10e-1)" "unprognostic (7.51e-2)" ZNF367 FLJ33970 ENSG00000165244 "Zinc finger protein 367" Q7RTV3 9 96385941-96418370 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 24.6" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 104.1;Megakaryocyte progenitors: 49.7;Migrating cytotrophoblasts: 41.2;Monocyte progenitors: 73.8;Neutrophil progenitors: 75.9;Paneth cells: 38.7;Platelets: 83.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA015319, HPA015785" Uncertain Supported Nucleoplasm NA Yes "Cluster 44: Bone marrow - Nuclear processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Cell proliferation" Nucleoplasm "HPA015319: , HPA015785: " "unprognostic (1.22e-1)" "unprognostic (1.04e-1)" "unprognostic (3.22e-2)" "unprognostic (2.21e-1)" "unprognostic (9.66e-2)" "unprognostic (5.17e-2)" "unprognostic (2.12e-1)" "unprognostic (3.14e-2)" "unprognostic (8.77e-3)" "unprognostic (5.97e-2)" "potential prognostic favorable (3.88e-6)" "unprognostic (9.27e-2)" "unprognostic (1.60e-3)" "unprognostic (4.92e-3)" "potential prognostic unfavorable (1.82e-4)" "potential prognostic unfavorable (2.29e-5)" "unprognostic (2.27e-2)" "unprognostic (1.04e-1)" "unprognostic (4.25e-2)" "unprognostic (2.80e-1)" "unprognostic (2.78e-1)" "unprognostic (1.96e-2)" "unprognostic (2.11e-1)" "unprognostic (7.08e-2)" "unprognostic (9.77e-3)" "unprognostic (3.13e-1)" "unprognostic (5.44e-2)" "unprognostic (6.27e-3)" "unprognostic (1.09e-1)" "unprognostic (2.68e-3)" "unprognostic (1.51e-1)" ZNF37A "KOX21, ZNF37" ENSG00000075407 "Zinc finger protein 37A" P17032 10 38094334-38150293 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Breast lactating cells: 2.4;Early primary spermatocytes: 2.1;Epicardial cells: 2.3" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003172 Approved Approved Vesicles NA NA "Cluster 24: Non-specific - Transcription" "Cluster 42: Retina - Visual perception" "Cluster 9: Non-specific - Receptor signaling" "Cluster 52: Non-specific - Mitochondria" "Cluster 78: Plasma cells - Antibody production & ER-stress response" 1 Vesicles "HPA003172: " "unprognostic (4.01e-2)" "unprognostic (1.77e-2)" "unprognostic (1.38e-1)" "unprognostic (1.60e-1)" "unprognostic (1.73e-1)" "unprognostic (2.39e-2)" "unprognostic (3.23e-2)" "unprognostic (1.31e-3)" "unprognostic (2.10e-3)" "unprognostic (8.14e-3)" "unprognostic (2.71e-2)" "unprognostic (6.58e-2)" "unprognostic (6.41e-2)" "unprognostic (4.68e-3)" "unprognostic (3.55e-1)" "unprognostic (1.53e-2)" "unprognostic (1.79e-1)" "unprognostic (7.78e-2)" "unprognostic (2.06e-2)" "unprognostic (3.50e-2)" "unprognostic (1.97e-1)" "unprognostic (5.45e-2)" "unprognostic (5.76e-3)" "unprognostic (1.14e-1)" "unprognostic (1.33e-2)" "unprognostic (6.08e-2)" "unprognostic (4.01e-1)" "unprognostic (1.43e-1)" "unprognostic (5.96e-2)" "unprognostic (1.15e-2)" "unprognostic (8.65e-2)" ZNF382 "FLJ14686, KS1" ENSG00000161298 "Zinc finger protein 382" Q96SR6 19 36604817-36634114 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.7;retina: 16.1" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 48.2;Brain inhibitory neurons: 48.0;Cardiomyocytes: 63.8;Choroid plexus epithelial cells: 33.1;Early spermatids: 34.2;Gonadotrophs: 34.8;Lactotrophs: 45.2;Other brain neurons: 37.3;Retinal horizontal cells: 52.1;Thyrotrophs: 50.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Pituitary gland - Lactotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049259 Approved Approved "Nuclear speckles" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 1 "Nuclear speckles" "HPA049259: " "unprognostic (1.60e-2)" "unprognostic (1.24e-2)" "unprognostic (1.05e-2)" "unprognostic (1.52e-1)" "unprognostic (4.64e-2)" "unprognostic (5.15e-2)" "unprognostic (3.19e-3)" "unprognostic (9.72e-2)" "potential prognostic favorable (2.34e-4)" "unprognostic (5.43e-3)" "unprognostic (2.58e-3)" "unprognostic (9.72e-3)" "unprognostic (2.99e-2)" "unprognostic (3.00e-2)" "unprognostic (2.99e-2)" "unprognostic (4.25e-1)" "unprognostic (2.13e-2)" "unprognostic (7.47e-2)" "unprognostic (4.67e-2)" "unprognostic (1.57e-2)" "unprognostic (3.92e-3)" "unprognostic (2.81e-2)" "unprognostic (2.40e-1)" "unprognostic (3.77e-1)" "unprognostic (1.95e-1)" ZNF383 "FLJ35863, Zfp383" ENSG00000188283 "Zinc finger protein 383" Q8NA42 19 37217926-37248740 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 60.7;Myonuclei: 73.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063945 Approved Supported "Nucleoplasm,Nuclear membrane" No No "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 55: Myocytes - Oxidative muscle function" 5 "Nucleoplasm, Nuclear membrane" "HPA063945: " "potential prognostic favorable (2.13e-4)" "unprognostic (6.68e-2)" "unprognostic (9.11e-2)" "unprognostic (3.03e-2)" "unprognostic (2.35e-1)" "unprognostic (1.56e-1)" "unprognostic (1.23e-2)" "unprognostic (4.56e-2)" "unprognostic (3.41e-2)" "unprognostic (2.04e-2)" "unprognostic (1.06e-3)" "potential prognostic favorable (5.98e-4)" "unprognostic (5.29e-3)" "unprognostic (5.54e-2)" "unprognostic (1.56e-1)" "unprognostic (3.05e-2)" "unprognostic (3.67e-2)" "unprognostic (1.77e-1)" "unprognostic (5.16e-2)" "unprognostic (1.18e-2)" "unprognostic (7.91e-2)" "unprognostic (7.04e-2)" "unprognostic (7.16e-3)" "unprognostic (2.52e-1)" "potential prognostic favorable (7.24e-5)" "unprognostic (2.15e-2)" "potential prognostic unfavorable (5.89e-4)" "unprognostic (1.29e-1)" "unprognostic (4.07e-2)" "unprognostic (5.13e-3)" "unprognostic (1.16e-1)" ZNF384 "CAGH1A, CIZ, NMP4, NP, TNRC1" ENSG00000126746 "Zinc finger protein 384" Q8TF68 12 6666477-6689572 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004051 Supported Approved Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 49: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 5 Nucleoplasm "HPA004051: " "unprognostic (8.03e-2)" "unprognostic (3.07e-1)" "unprognostic (2.89e-2)" "unprognostic (2.40e-2)" "unprognostic (4.36e-2)" "unprognostic (1.02e-1)" "unprognostic (1.48e-1)" "unprognostic (2.94e-1)" "unprognostic (7.29e-2)" "unprognostic (1.23e-2)" "unprognostic (7.36e-3)" "unprognostic (1.49e-3)" "unprognostic (8.52e-2)" "potential prognostic unfavorable (1.39e-4)" "unprognostic (1.00e-1)" "unprognostic (1.49e-3)" "potential prognostic unfavorable (5.41e-5)" "unprognostic (6.20e-2)" "unprognostic (5.26e-2)" "unprognostic (2.04e-2)" "unprognostic (2.01e-2)" "unprognostic (4.00e-2)" "unprognostic (3.81e-3)" "unprognostic (1.56e-1)" "unprognostic (3.37e-3)" "unprognostic (1.73e-2)" "unprognostic (9.58e-2)" "unprognostic (7.01e-2)" "unprognostic (2.63e-1)" "unprognostic (1.28e-1)" "unprognostic (1.21e-1)" ZNF385A "DKFZp586G1122, Hzf, ZFP385, ZNF385" ENSG00000161642 "Zinc finger protein 385A" Q96PM9 12 54369133-54391298 "Predicted intracellular proteins" "DNA damage, Transcription, Transcription regulation, Translation regulation" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 232.8;skin 1: 149.8" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 163.5;Esophageal suprabasal cells: 94.0;Megakaryocytes: 111.3;monocytes: 92.7;Ocular epithelial cells: 89.5;Retinal bipolar cells: 166.1;Retinal horizontal cells: 92.2;Retinal pigment epithelial cells: 149.2;Rod photoreceptor cells: 175.7;Suprabasal keratinocytes: 96.9;Syncytiotrophoblasts: 140.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "classical monocyte: 29.3;intermediate monocyte: 32.9;myeloid DC: 32.0;non-classical monocyte: 26.0" "Group enriched" "Detected in many" 11 "dendritic cells: 32.0;monocytes: 32.9" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skin - Keratinocyte (other), Spleen - Macrophages, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076214 Supported Nucleoplasm,Cytosol NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 79: Photoreceptor cells - Phototransduction" Cytosol Nucleoplasm "HPA076214: " "unprognostic (2.20e-1)" "unprognostic (3.97e-1)" "unprognostic (5.08e-1)" "unprognostic (3.89e-1)" "unprognostic (6.35e-2)" "unprognostic (5.41e-3)" "unprognostic (6.28e-2)" "unprognostic (3.11e-1)" "unprognostic (1.30e-3)" "unprognostic (1.36e-2)" "unprognostic (2.80e-3)" "unprognostic (1.60e-1)" "unprognostic (2.62e-1)" "unprognostic (7.36e-2)" "unprognostic (8.16e-2)" "unprognostic (3.74e-1)" "unprognostic (3.50e-2)" "unprognostic (3.35e-1)" "unprognostic (3.82e-2)" "unprognostic (2.61e-1)" "unprognostic (1.89e-2)" "unprognostic (1.90e-1)" "potential prognostic unfavorable (4.85e-4)" "unprognostic (1.52e-1)" "unprognostic (5.06e-3)" "unprognostic (1.12e-1)" "unprognostic (1.26e-1)" "unprognostic (2.19e-1)" "unprognostic (9.51e-2)" "unprognostic (4.91e-2)" "unprognostic (1.87e-1)" ZNF385B "FLJ25270, ZNF533" ENSG00000144331 "Zinc finger protein 385B" Q569K4 2 179441982-179861612 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 82.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 2771.6;Brain excitatory neurons: 584.5;Brain inhibitory neurons: 570.6;Cone photoreceptor cells: 720.4;Myonuclei: 871.7;Retinal bipolar cells: 2654.9;Rod photoreceptor cells: 1660.8;Sertoli cells: 1126.9;Transitional alveolar cells: 1160.6" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 30.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "lymphoma: 12.4;prostate cancer: 14.3" "Breast - Fibroblasts, Liver - Hepatocytes, Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046086 Supported "Nucleoli fibrillar center" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 37: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "Nucleoli fibrillar center" "HPA046086: " "potential prognostic favorable (1.37e-5)" "unprognostic (2.75e-3)" "unprognostic (3.04e-2)" "unprognostic (1.33e-1)" "unprognostic (9.59e-3)" "unprognostic (2.40e-1)" "potential prognostic favorable (4.21e-5)" "unprognostic (5.71e-3)" "potential prognostic favorable (3.59e-4)" "unprognostic (3.40e-3)" "potential prognostic favorable (1.76e-5)" "unprognostic (1.53e-2)" "unprognostic (7.75e-2)" "unprognostic (4.82e-2)" "unprognostic (1.90e-2)" "unprognostic (4.32e-2)" "unprognostic (2.08e-1)" "unprognostic (3.25e-1)" "unprognostic (5.16e-2)" "unprognostic (7.22e-2)" ZNF385C ENSG00000187595 "Zinc finger protein 385C" 17 42025576-42098479 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 9.1;testis: 6.5" "Cell type enhanced" "Detected in many" "Early spermatids: 47.4;Epididymal clear cells: 16.3;Late spermatids: 17.6;pDCs: 21.1;Pituitary stem cells: 14.5;Retinal amacrine cells: 26.0;Sertoli cells: 55.1" "Cell type enriched" "Detected in many" 6 "cerebellar inhibitory: 31.7" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 5 "cerebellum: 17.0" "Immune cell enriched" "Detected in single" 9 "plasmacytoid DC: 1.3" "Lineage enriched" "Detected in single" 9 "dendritic cells: 1.3" "Cancer enhanced" "Detected in some" "cervical cancer: 4.3" "Region enriched" "Detected in many" 12 "cerebellum: 28.3" "Region enhanced" "Detected in all" "cerebellum: 29.7" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 67: Testis - Mixed function" "Cluster 35: Non-specific - DNA binding" "Cluster 55: Lymphoma - Immune response" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" 1 "unprognostic (4.70e-2)" "unprognostic (1.18e-2)" "unprognostic (1.52e-2)" "unprognostic (2.89e-2)" "unprognostic (1.39e-1)" "unprognostic (3.84e-1)" "unprognostic (6.53e-2)" "unprognostic (6.65e-2)" "unprognostic (2.67e-3)" "unprognostic (1.53e-1)" "unprognostic (2.65e-1)" "unprognostic (1.44e-1)" "unprognostic (2.10e-1)" "unprognostic (3.73e-1)" "unprognostic (5.27e-2)" "unprognostic (3.31e-2)" "unprognostic (2.98e-2)" "unprognostic (1.09e-1)" "unprognostic (2.03e-1)" "unprognostic (1.76e-2)" "unprognostic (5.57e-2)" "unprognostic (2.18e-1)" "unprognostic (6.18e-2)" "unprognostic (1.99e-1)" "unprognostic (1.84e-1)" "unprognostic (7.72e-2)" "unprognostic (1.66e-1)" ZNF385D "FLJ22419, ZNF659" ENSG00000151789 "Zinc finger protein 385D" Q9H6B1 3 21412218-22373321 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 23.6;testis: 13.1" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 1649.6;Brain inhibitory neurons: 880.9;Hematopoietic stem cells: 3544.1;Megakaryocyte-Erythroid progenitors: 2487.3;Müller glia: 949.2;Neutrophil progenitors: 760.2;Retinal amacrine cells: 1057.3;Retinal ganglion cells: 907.8;Retinal horizontal cells: 917.5;Vascular endothelial cells: 776.8" "Cell type enhanced" "Detected in all" "deep-layer near-projecting: 3181.6;LAMP5-LHX6 and Chandelier: 3344.5;upper rhombic lip: 5757.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "thyroid cancer: 1.8" "Breast - Endothelial cells, Minor Salivary Gland - Endothelial cells, Pancreas - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" HPA036190 Uncertain NA NA "Cluster 67: Testis - Mixed function" "Cluster 2: Neurons - Nucleosome" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 2: Cerebellar granular cells - Neuronal signaling" "HPA036190: " "unprognostic (3.01e-1)" "unprognostic (9.18e-2)" "unprognostic (4.38e-2)" "unprognostic (7.11e-2)" "unprognostic (4.49e-2)" "potential prognostic unfavorable (7.44e-4)" "unprognostic (8.87e-3)" "unprognostic (1.32e-1)" "unprognostic (2.39e-2)" "unprognostic (7.53e-2)" "unprognostic (2.94e-1)" "unprognostic (3.39e-2)" "unprognostic (1.02e-1)" "unprognostic (2.18e-1)" "unprognostic (5.77e-2)" ZNF391 dJ153G14.3 ENSG00000124613 "Zinc finger protein 391" Q9UJN7 6 27374615-27403908 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 72.0;Early spermatids: 84.7;Endometrial ciliated cells: 36.1;Fallopian tube ciliated cells: 30.9;Late primary spermatocytes: 54.6;Respiratory ciliated cells: 40.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" "Low region specificity" "Detected in all" HPA050886 Uncertain NA NA "Cluster 24: Non-specific - Transcription" "Cluster 65: Brain - Transcription" "Cluster 53: Neurons - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" "HPA050886: " "unprognostic (5.64e-2)" "unprognostic (3.59e-1)" "unprognostic (1.51e-1)" "unprognostic (1.35e-1)" "unprognostic (2.87e-2)" "unprognostic (1.19e-1)" "unprognostic (1.74e-1)" "unprognostic (2.01e-2)" "unprognostic (2.87e-2)" "potential prognostic favorable (1.29e-4)" "unprognostic (2.28e-2)" "unprognostic (3.43e-1)" "unprognostic (4.02e-3)" "unprognostic (3.42e-1)" "unprognostic (4.15e-2)" "unprognostic (1.64e-2)" "potential prognostic favorable (3.33e-4)" "unprognostic (1.24e-2)" "unprognostic (6.99e-2)" "unprognostic (8.60e-2)" "unprognostic (3.25e-1)" "unprognostic (3.28e-3)" "unprognostic (7.77e-2)" "unprognostic (9.74e-2)" "unprognostic (4.09e-2)" "unprognostic (2.18e-1)" "unprognostic (1.15e-2)" "unprognostic (6.22e-2)" ZNF394 "FLJ12298, ZKSCAN14, ZSCAN46" ENSG00000160908 "Zinc finger protein 394" Q53GI3 7 99473877-99504857 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "bone marrow: 91.4" "Cell type enhanced" "Detected in many" "Neutrophil progenitors: 164.7;Neutrophils: 273.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051421, HPA054639" Approved Enhanced Nucleoplasm,Cytosol Yes No "Cluster 42: Non-specific - Vesicular transport" "Cluster 15: Bone marrow - Innate immune response" "Cluster 25: Non-specific - Transcription" "Cluster 39: Non-specific - Transcription" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 7 Nucleoplasm Cytosol "HPA051421: , HPA054639: " "unprognostic (8.57e-3)" "unprognostic (1.01e-3)" "unprognostic (1.19e-1)" "unprognostic (6.89e-2)" "unprognostic (1.45e-1)" "unprognostic (1.57e-3)" "unprognostic (3.49e-2)" "unprognostic (2.89e-2)" "unprognostic (3.78e-3)" "unprognostic (1.17e-2)" "unprognostic (7.34e-3)" "potential prognostic favorable (2.79e-4)" "unprognostic (1.39e-1)" "unprognostic (4.82e-1)" "unprognostic (3.54e-2)" "unprognostic (1.10e-2)" "unprognostic (7.26e-3)" "unprognostic (4.30e-3)" "unprognostic (9.03e-2)" "unprognostic (3.10e-1)" "unprognostic (3.34e-2)" "unprognostic (2.98e-1)" "unprognostic (2.45e-2)" "unprognostic (2.10e-1)" "unprognostic (2.83e-1)" "unprognostic (2.65e-1)" "unprognostic (5.23e-2)" "unprognostic (2.81e-2)" "unprognostic (2.62e-2)" "unprognostic (3.38e-2)" "unprognostic (2.40e-3)" ZNF395 "DKFZp434K1210, HDBP2, PBF, PRF-1" ENSG00000186918 "Zinc finger protein 395" Q9H8N7 8 28345590-28402701 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bergmann glia: 84.2;Pancreatic acinar cells: 125.0;Pancreatic islet cells: 78.8" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 5 "Kidney Renal Clear Cell Carcinoma (TCGA): 158.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049382, HPA076275" Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 54: Non-specific - Ribosome" "Cluster 39: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 22: Non-specific - Basic cellular functions" 13 Nucleoplasm Cytosol "HPA049382: , HPA076275: " "unprognostic (1.03e-2)" "unprognostic (1.25e-1)" "unprognostic (4.10e-2)" "unprognostic (3.27e-2)" "unprognostic (3.72e-2)" "unprognostic (7.62e-2)" "unprognostic (1.50e-2)" "potential prognostic unfavorable (3.05e-6)" "unprognostic (4.78e-2)" "unprognostic (2.02e-3)" "potential prognostic favorable (6.82e-6)" "unprognostic (1.13e-3)" "unprognostic (8.22e-2)" "potential prognostic unfavorable (5.74e-5)" "unprognostic (4.15e-2)" "unprognostic (9.36e-2)" "unprognostic (9.01e-2)" "unprognostic (7.96e-2)" "unprognostic (1.05e-1)" "unprognostic (1.83e-1)" "unprognostic (8.70e-3)" "unprognostic (1.43e-1)" "unprognostic (3.57e-2)" "unprognostic (7.21e-2)" "potential prognostic favorable (3.49e-4)" "unprognostic (6.67e-2)" "unprognostic (4.25e-2)" "unprognostic (3.78e-1)" "unprognostic (4.73e-1)" "unprognostic (1.93e-1)" "unprognostic (2.32e-1)" ZNF396 "FLJ31213, ZSCAN14" ENSG00000186496 "Zinc finger protein 396" Q96N95 18 35366694-35377337 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 17.8;Fallopian tube ciliated cells: 20.9;Late primary spermatocytes: 14.4;Late spermatids: 15.2;Neutrophils: 13.5;Respiratory ciliated cells: 21.4" "Cell type enhanced" "Detected in many" "ependymal cell: 13.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 8.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 8.8" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Prostate - Prostate basal glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" HPA006686 Uncertain NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 54: Immune cells - T cell receptor" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 3 "HPA006686: " "unprognostic (2.38e-2)" "unprognostic (1.04e-1)" "unprognostic (4.12e-1)" "unprognostic (6.69e-2)" "unprognostic (2.01e-1)" "unprognostic (1.00e-1)" "unprognostic (1.31e-1)" "unprognostic (1.33e-1)" "unprognostic (3.02e-3)" "potential prognostic unfavorable (6.42e-4)" "unprognostic (1.52e-1)" "potential prognostic favorable (9.52e-4)" "unprognostic (1.64e-2)" "unprognostic (1.24e-3)" "unprognostic (1.96e-2)" "unprognostic (4.32e-1)" "unprognostic (2.32e-1)" "unprognostic (5.30e-2)" "unprognostic (7.46e-2)" "unprognostic (9.28e-2)" "unprognostic (1.24e-1)" "unprognostic (2.19e-2)" "unprognostic (1.30e-2)" "unprognostic (1.23e-1)" "unprognostic (1.14e-3)" "unprognostic (8.72e-2)" "unprognostic (5.57e-2)" "unprognostic (2.49e-1)" "unprognostic (7.07e-2)" "unprognostic (4.05e-1)" ZNF397 "MGC13250, ZNF47, ZSCAN15" ENSG00000186812 "Zinc finger protein 397" Q8NF99 18 35241030-35267133 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 349.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026087 Uncertain Approved "Nucleoli,Plasma membrane,Microtubules,Cytosol" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 61: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 13: Non-specific - Mixed function" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 11 "Nucleoli, Plasma membrane, Cytosol" Microtubules "HPA026087: " "unprognostic (8.29e-3)" "unprognostic (3.35e-2)" "unprognostic (6.45e-3)" "unprognostic (7.21e-2)" "unprognostic (2.46e-1)" "unprognostic (1.71e-2)" "unprognostic (4.01e-1)" "potential prognostic favorable (4.59e-4)" "unprognostic (1.49e-2)" "unprognostic (7.82e-2)" "unprognostic (1.18e-2)" "potential prognostic favorable (2.97e-4)" "potential prognostic favorable (3.39e-4)" "unprognostic (1.06e-2)" "unprognostic (2.93e-1)" "unprognostic (3.60e-2)" "unprognostic (3.27e-2)" "unprognostic (1.04e-1)" "unprognostic (1.13e-3)" "unprognostic (4.95e-2)" "unprognostic (2.70e-1)" "unprognostic (1.50e-3)" "unprognostic (1.28e-1)" "unprognostic (1.02e-2)" "unprognostic (7.58e-2)" "unprognostic (8.36e-2)" "unprognostic (7.54e-3)" "unprognostic (1.07e-1)" "unprognostic (1.35e-1)" "unprognostic (3.72e-2)" "unprognostic (2.77e-2)" ZNF398 "KIAA1339, P51, P71, ZER6" ENSG00000197024 "Zinc finger protein 398" Q8TD17 7 149126416-149183042 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073151 Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 39: Testis - Nuclear processes" "Cluster 16: Non-specific - Transcription" "Cluster 39: Non-specific - Transcription" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 25 "Nucleoplasm, Nuclear membrane" "HPA073151: " "unprognostic (1.05e-2)" "unprognostic (1.08e-1)" "unprognostic (1.75e-2)" "unprognostic (1.51e-1)" "unprognostic (1.50e-1)" "unprognostic (2.51e-3)" "unprognostic (1.32e-1)" "unprognostic (1.72e-2)" "unprognostic (2.15e-2)" "unprognostic (7.22e-3)" "potential prognostic favorable (2.02e-6)" "unprognostic (2.01e-3)" "unprognostic (2.32e-1)" "unprognostic (5.56e-3)" "unprognostic (2.59e-1)" "unprognostic (7.72e-2)" "unprognostic (3.54e-2)" "unprognostic (2.09e-1)" "unprognostic (1.58e-2)" "unprognostic (5.85e-2)" "unprognostic (2.51e-1)" "unprognostic (3.67e-1)" "unprognostic (1.55e-2)" "unprognostic (5.23e-2)" "unprognostic (8.84e-2)" "unprognostic (4.49e-2)" "unprognostic (1.12e-2)" "unprognostic (1.51e-1)" "unprognostic (1.63e-1)" "unprognostic (1.05e-2)" "unprognostic (8.30e-3)" ZNF404 ENSG00000176222 "Zinc finger protein 404" Q494X3 19 43872365-43901385 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 17.0;Astrocytes: 29.0;Bergmann glia: 27.0;Cardiomyocytes: 60.3;Ependymal cells: 16.4;Oligodendrocytes: 19.5;Pituicytes/FSCs: 18.9;Pituitary stem cells: 16.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA032014, HPA063607" Uncertain Supported "Nucleoli,Nucleoli rim,Intermediate filaments" NA Yes "Cluster 65: Brain - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 1 "Nucleoli, Nucleoli rim" "Intermediate filaments" "HPA032014: , HPA063607: " "unprognostic (5.56e-3)" "unprognostic (5.18e-2)" "unprognostic (8.68e-2)" "unprognostic (1.32e-2)" "unprognostic (1.51e-2)" "unprognostic (2.81e-2)" "unprognostic (6.49e-2)" "potential prognostic unfavorable (4.61e-4)" "unprognostic (4.89e-2)" "unprognostic (6.53e-2)" "unprognostic (5.04e-3)" "unprognostic (3.13e-1)" "unprognostic (1.24e-1)" "unprognostic (2.87e-1)" "unprognostic (1.10e-1)" "unprognostic (3.91e-2)" "unprognostic (2.26e-1)" "unprognostic (2.92e-1)" "potential prognostic favorable (8.00e-5)" "unprognostic (8.14e-2)" "unprognostic (1.03e-2)" "unprognostic (2.91e-1)" "unprognostic (2.82e-2)" "unprognostic (6.79e-3)" "unprognostic (3.14e-2)" "unprognostic (2.28e-1)" "potential prognostic unfavorable (6.81e-4)" ZNF407 "FLJ13839, FLJ20307, KIAA1703" ENSG00000215421 "Zinc finger protein 407" Q9C0G0 18 74597870-75065671 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Choroid plexus epithelial cells: 526.3;Neutrophil progenitors: 545.1;Neutrophils: 573.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028255, HPA041673" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 13: Non-specific - Mixed function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" Nucleoplasm "Plasma membrane" "HPA028255: , HPA041673: " "unprognostic (1.85e-1)" "unprognostic (1.36e-1)" "unprognostic (2.41e-1)" "unprognostic (3.27e-2)" "unprognostic (9.86e-2)" "unprognostic (3.36e-1)" "unprognostic (5.14e-2)" "unprognostic (6.62e-3)" "unprognostic (1.94e-2)" "unprognostic (2.64e-1)" "validated prognostic favorable (1.53e-5)" "validated prognostic favorable (2.03e-4)" "unprognostic (2.40e-1)" "unprognostic (1.10e-1)" "unprognostic (9.91e-2)" "unprognostic (5.16e-2)" "unprognostic (1.12e-1)" "unprognostic (2.68e-1)" "unprognostic (1.47e-1)" "unprognostic (1.73e-2)" "unprognostic (3.52e-2)" "unprognostic (1.58e-1)" "unprognostic (4.32e-3)" "unprognostic (1.65e-1)" "unprognostic (8.51e-2)" "unprognostic (1.02e-2)" "unprognostic (1.12e-1)" "unprognostic (5.95e-2)" "unprognostic (2.34e-1)" "unprognostic (1.41e-2)" "unprognostic (3.84e-1)" ZNF408 FLJ12827 ENSG00000175213 "Zinc finger protein 408" Q9H9D4 11 46701030-46705912 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 25.8;Oocytes: 27.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017892 Uncertain Approved "Centriolar satellite,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 24: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 24: Non-specific - Unknown function" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 64 "Centriolar satellite, Cytosol" "HPA017892: " "unprognostic (3.52e-1)" "unprognostic (1.73e-1)" "unprognostic (2.47e-1)" "unprognostic (2.01e-2)" "unprognostic (2.22e-2)" "unprognostic (9.47e-2)" "unprognostic (6.10e-2)" "unprognostic (1.54e-1)" "unprognostic (1.11e-1)" "unprognostic (2.33e-2)" "unprognostic (4.11e-2)" "unprognostic (1.78e-1)" "unprognostic (1.77e-2)" "potential prognostic unfavorable (1.50e-7)" "unprognostic (9.23e-3)" "unprognostic (1.74e-2)" "unprognostic (3.61e-2)" "unprognostic (2.35e-1)" "unprognostic (3.49e-1)" "unprognostic (2.81e-1)" "unprognostic (2.70e-1)" "unprognostic (2.41e-2)" "unprognostic (2.60e-1)" "unprognostic (2.73e-2)" "unprognostic (4.99e-2)" "unprognostic (2.73e-3)" "unprognostic (1.63e-2)" "unprognostic (2.28e-2)" "unprognostic (1.04e-1)" "unprognostic (5.15e-2)" "unprognostic (4.54e-1)" ZNF41 "MGC8941, MRX89" ENSG00000147124 "Zinc finger protein 41" P51814 X 47445178-47483222 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 149.6;Myonuclei: 83.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069102 Supported Approved Nucleoplasm NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 36: Non-specific - mRNA processing" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 2 Nucleoplasm "HPA069102: " "unprognostic (3.08e-2)" "unprognostic (2.63e-2)" "unprognostic (1.00e-1)" "unprognostic (1.38e-1)" "unprognostic (2.08e-1)" "unprognostic (2.66e-1)" "unprognostic (9.07e-2)" "unprognostic (2.71e-2)" "unprognostic (2.70e-3)" "potential prognostic unfavorable (1.40e-4)" "potential prognostic favorable (9.53e-5)" "unprognostic (2.54e-3)" "unprognostic (1.01e-1)" "unprognostic (3.11e-1)" "unprognostic (2.74e-2)" "unprognostic (9.16e-3)" "unprognostic (1.11e-1)" "unprognostic (3.77e-2)" "unprognostic (4.43e-1)" "unprognostic (2.34e-2)" "unprognostic (1.17e-2)" "unprognostic (1.49e-1)" "unprognostic (6.01e-2)" "unprognostic (5.72e-2)" "unprognostic (3.49e-2)" "unprognostic (2.98e-1)" "unprognostic (3.41e-2)" "unprognostic (1.41e-1)" "unprognostic (1.11e-1)" "unprognostic (5.16e-3)" "unprognostic (9.48e-2)" ZNF410 "APA-1, APA1" ENSG00000119725 "Zinc finger protein 410" Q86VK4 14 73886617-73932521 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 37.7;Bergmann glia: 36.0;Brain excitatory neurons: 30.4;Brain inhibitory neurons: 28.1;Choroid plexus epithelial cells: 47.8;Ependymal cells: 45.2;Microglia: 33.9;Oligodendrocyte progenitor cells: 30.6;Oligodendrocytes: 35.4;Other brain neurons: 24.4;Tuft cells: 11.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003610 Supported Nucleoplasm,Cytosol NA No "Cluster 42: Non-specific - Vesicular transport" "Cluster 39: Testis - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 22: Non-specific - Basic cellular functions" 12 Nucleoplasm Cytosol "HPA003610: " "unprognostic (1.54e-1)" "unprognostic (3.14e-1)" "potential prognostic unfavorable (6.41e-5)" "unprognostic (4.49e-3)" "unprognostic (3.44e-1)" "unprognostic (9.01e-3)" "unprognostic (1.74e-2)" "unprognostic (5.58e-3)" "unprognostic (4.56e-2)" "unprognostic (5.23e-3)" "unprognostic (2.38e-2)" "unprognostic (3.73e-2)" "unprognostic (2.86e-1)" "potential prognostic unfavorable (3.11e-5)" "unprognostic (8.59e-2)" "unprognostic (2.27e-2)" "unprognostic (2.59e-1)" "unprognostic (1.39e-2)" "unprognostic (2.15e-1)" "unprognostic (4.08e-1)" "unprognostic (4.22e-2)" "unprognostic (1.95e-1)" "potential prognostic unfavorable (7.36e-4)" "unprognostic (9.20e-2)" "unprognostic (4.49e-1)" "unprognostic (1.10e-1)" "unprognostic (6.20e-2)" "unprognostic (5.31e-2)" "unprognostic (1.39e-1)" "unprognostic (3.48e-1)" "unprognostic (1.89e-1)" ZNF414 "MGC15716, Zfp414" ENSG00000133250 "Zinc finger protein 414" Q96IQ9 19 8509678-8514167 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 150.4;Oocytes: 165.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053769 Approved Approved Nucleoplasm NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 64: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 23: Non-specific - Transcription" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 66 Nucleoplasm "HPA053769: " "unprognostic (3.82e-1)" "unprognostic (9.42e-2)" "unprognostic (1.71e-1)" "unprognostic (2.00e-1)" "unprognostic (1.02e-1)" "unprognostic (2.12e-1)" "unprognostic (6.16e-2)" "unprognostic (3.75e-1)" "potential prognostic favorable (6.78e-6)" "unprognostic (2.99e-1)" "unprognostic (4.99e-3)" "unprognostic (3.05e-1)" "unprognostic (1.55e-1)" "unprognostic (1.28e-1)" "unprognostic (3.24e-2)" "unprognostic (1.68e-1)" "unprognostic (2.20e-1)" "unprognostic (5.55e-2)" "unprognostic (3.96e-2)" "unprognostic (1.35e-1)" "unprognostic (4.57e-2)" "unprognostic (5.79e-3)" "unprognostic (2.03e-1)" "unprognostic (1.12e-1)" "unprognostic (8.90e-2)" "potential prognostic favorable (1.60e-4)" "unprognostic (1.04e-1)" "unprognostic (3.18e-1)" "unprognostic (2.89e-2)" "unprognostic (8.62e-2)" "unprognostic (1.21e-1)" ZNF415 ENSG00000170954 "Zinc finger protein 415" Q09FC8 19 53107879-53133077 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 93.2;Late primary spermatocytes: 88.2;Late spermatids: 68.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Liver - Hepatic stellate cells, Spleen - Endothelial cells, Testis - Early spermatids" HPA005553 Approved Approved "Nucleoli fibrillar center,Microtubules" NA NA "Cluster 32: Basophils - Transcription" "Cluster 35: Non-specific - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 4: Non-specific - Transcription" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 2 "Nucleoli fibrillar center, Microtubules" "HPA005553: " "potential prognostic favorable (2.43e-5)" "unprognostic (1.07e-1)" "unprognostic (3.76e-2)" "unprognostic (3.73e-2)" "unprognostic (2.93e-1)" "unprognostic (7.27e-2)" "unprognostic (1.79e-1)" "unprognostic (8.52e-2)" "potential prognostic unfavorable (5.60e-4)" "potential prognostic favorable (5.09e-4)" "unprognostic (1.08e-3)" "unprognostic (3.53e-1)" "unprognostic (1.33e-2)" "unprognostic (2.54e-1)" "unprognostic (1.05e-1)" "potential prognostic unfavorable (7.51e-4)" "unprognostic (2.11e-2)" "unprognostic (1.95e-1)" "unprognostic (2.89e-3)" "unprognostic (3.78e-2)" "unprognostic (7.51e-2)" "unprognostic (1.13e-1)" "unprognostic (9.30e-2)" "unprognostic (1.03e-1)" "unprognostic (3.11e-2)" "unprognostic (1.03e-1)" "unprognostic (1.37e-1)" "unprognostic (5.65e-2)" "unprognostic (3.99e-1)" ZNF416 FLJ20557 ENSG00000083817 "Zinc finger protein 416" Q9BWM5 19 57571566-57578911 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 26.8;Late primary spermatocytes: 8.6;Oocytes: 18.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skin - Keratinocyte (other)" HPA078491 Approved "Nucleoplasm,Nuclear speckles" NA No "Cluster 3: Non-specific - Nuclear processes" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" Nucleoplasm "Nuclear speckles" "HPA078491: " "unprognostic (2.79e-1)" "unprognostic (2.20e-1)" "unprognostic (1.07e-1)" "unprognostic (2.37e-1)" "unprognostic (4.18e-2)" "unprognostic (9.08e-3)" "unprognostic (7.68e-2)" "unprognostic (2.31e-1)" "unprognostic (2.74e-2)" "unprognostic (9.73e-2)" "validated prognostic favorable (5.66e-9)" "validated prognostic favorable (3.19e-5)" "unprognostic (3.49e-2)" "unprognostic (1.60e-2)" "unprognostic (5.15e-2)" "unprognostic (3.44e-1)" "unprognostic (6.02e-2)" "unprognostic (2.45e-2)" "unprognostic (1.51e-1)" "unprognostic (1.11e-1)" "unprognostic (1.41e-1)" "unprognostic (2.10e-2)" "unprognostic (1.35e-1)" "unprognostic (2.43e-2)" "unprognostic (1.15e-3)" "unprognostic (3.23e-2)" "unprognostic (1.69e-1)" "unprognostic (1.44e-1)" "unprognostic (2.46e-1)" "unprognostic (2.16e-2)" "unprognostic (2.40e-1)" ZNF417 MGC34079 ENSG00000173480 "Zinc finger protein 417" Q8TAU3 19 57900296-57916610 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in single" 4 "Epididymal principal cells: 4.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA042125, HPA043288, HPA056213" Uncertain Approved Nucleoplasm,Nucleoli NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 22: Epididymis - Mixed function" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 4: Non-specific - Transcription" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 149 Nucleoplasm Nucleoli "HPA042125: , HPA043288: , HPA056213: " "unprognostic (7.16e-3)" "unprognostic (1.86e-1)" "unprognostic (1.88e-1)" "unprognostic (1.09e-1)" "unprognostic (1.20e-1)" "unprognostic (1.17e-1)" "unprognostic (2.22e-1)" "unprognostic (1.59e-2)" "unprognostic (4.10e-3)" "unprognostic (4.24e-3)" "unprognostic (7.43e-3)" "unprognostic (9.90e-3)" "unprognostic (2.70e-2)" "unprognostic (4.79e-2)" "unprognostic (9.11e-2)" "unprognostic (6.60e-3)" "unprognostic (4.44e-2)" "unprognostic (1.01e-1)" "unprognostic (2.35e-1)" "unprognostic (6.12e-2)" "unprognostic (1.14e-1)" "unprognostic (2.94e-3)" "unprognostic (3.08e-2)" "unprognostic (9.12e-2)" "unprognostic (2.43e-2)" "unprognostic (5.78e-2)" "unprognostic (3.74e-3)" "unprognostic (8.19e-2)" "unprognostic (1.23e-1)" "unprognostic (4.33e-1)" "unprognostic (2.21e-1)" ZNF418 "FLJ31551, KIAA1956" ENSG00000196724 "Zinc finger protein 418" Q8TF45 19 57921882-57935402 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 22.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 10.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Skeletal muscle - Fibroblasts" "HPA043800, HPA053762, HPA072145" Approved Uncertain Nucleoplasm NA NA "Cluster 32: Basophils - Transcription" "Cluster 65: Brain - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 2 Nucleoplasm "HPA043800: , HPA053762: , HPA072145: " "unprognostic (5.86e-2)" "unprognostic (1.58e-1)" "unprognostic (9.32e-2)" "unprognostic (3.68e-1)" "unprognostic (3.03e-1)" "unprognostic (4.06e-2)" "unprognostic (2.58e-1)" "validated prognostic favorable (2.99e-4)" "validated prognostic favorable (5.46e-4)" "potential prognostic favorable (5.92e-4)" "unprognostic (9.08e-2)" "unprognostic (6.52e-2)" "unprognostic (1.21e-1)" "unprognostic (1.07e-1)" "unprognostic (3.34e-1)" "unprognostic (1.92e-1)" "unprognostic (2.25e-1)" "unprognostic (1.39e-2)" "unprognostic (1.70e-2)" "unprognostic (7.03e-3)" "unprognostic (3.20e-1)" "unprognostic (2.37e-2)" "unprognostic (6.64e-2)" "unprognostic (2.15e-1)" "unprognostic (2.63e-1)" "unprognostic (2.75e-2)" ZNF419 "ZAPHIR, ZNF419A" ENSG00000105136 "Zinc finger protein 419" Q96HQ0 19 57487711-57496098 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Epididymal basal cells: 1.1;Epididymal principal cells: 1.7;Parietal cells: 3.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Minor Salivary Gland - Minor salivary glandular cells" "HPA003152, HPA003274" Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 15: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 3 Nucleoplasm "Nucleoli fibrillar center" "HPA003152: , HPA003274: " "unprognostic (4.73e-3)" "unprognostic (6.69e-2)" "unprognostic (9.09e-3)" "unprognostic (3.97e-3)" "unprognostic (4.68e-1)" "unprognostic (2.80e-1)" "unprognostic (1.04e-1)" "unprognostic (9.44e-2)" "unprognostic (1.60e-1)" "unprognostic (8.83e-2)" "unprognostic (1.69e-2)" "unprognostic (2.55e-3)" "unprognostic (1.31e-2)" "unprognostic (2.43e-2)" "unprognostic (1.90e-1)" "unprognostic (2.96e-1)" "unprognostic (2.01e-1)" "unprognostic (2.84e-1)" "unprognostic (2.05e-1)" "unprognostic (2.68e-1)" "unprognostic (2.24e-1)" "potential prognostic favorable (2.74e-4)" "unprognostic (4.00e-3)" "potential prognostic unfavorable (7.86e-4)" "unprognostic (3.94e-3)" "unprognostic (1.47e-1)" "unprognostic (1.60e-1)" "unprognostic (6.23e-2)" "unprognostic (3.83e-2)" "unprognostic (2.44e-2)" "unprognostic (1.11e-1)" ZNF420 FLJ32191 ENSG00000197050 "Zinc finger protein 420" Q8TAQ5 19 37007857-37130368 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 151.8;Early spermatids: 224.5;Late primary spermatocytes: 162.7;Late spermatids: 266.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" HPA059675 Approved Approved Nucleoplasm NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 13 Nucleoplasm "HPA059675: " "unprognostic (1.00e-2)" "unprognostic (1.96e-1)" "unprognostic (2.81e-1)" "unprognostic (2.43e-1)" "unprognostic (2.83e-1)" "unprognostic (7.80e-2)" "unprognostic (2.27e-2)" "unprognostic (6.26e-2)" "unprognostic (3.98e-2)" "unprognostic (1.20e-2)" "validated prognostic favorable (2.00e-8)" "validated prognostic favorable (1.33e-4)" "unprognostic (1.31e-1)" "unprognostic (4.97e-2)" "unprognostic (2.44e-1)" "unprognostic (2.37e-1)" "unprognostic (4.61e-2)" "unprognostic (1.42e-1)" "unprognostic (1.15e-1)" "unprognostic (1.32e-1)" "unprognostic (3.71e-2)" "unprognostic (1.77e-1)" "unprognostic (3.35e-1)" "unprognostic (4.66e-2)" "potential prognostic favorable (1.73e-6)" "unprognostic (9.76e-2)" "unprognostic (4.37e-2)" "unprognostic (3.47e-1)" "unprognostic (4.85e-2)" "unprognostic (5.88e-2)" "unprognostic (1.68e-1)" ZNF423 "Ebfaz, hOAZ, JBTS19, KIAA0760, NPHP14, OAZ, Zfp104" ENSG00000102935 "Zinc finger protein 423" Q2M1K9 16 49487524-49857919 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Ciliopathy, Disease variant, Joubert syndrome, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 25.8" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 127.6;Astrocytes: 117.5;Bergmann glia: 112.6;Fibro-adipogenic progenitors: 122.1;Late spermatids: 152.7;Leydig cells: 93.9;Myonuclei: 321.7;Peritubular myoid cells: 126.9;Somatotrophs: 146.3;Thyrotrophs: 150.0;Vascular endothelial cells: 114.0" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 200.3;endothelial cell: 228.5" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 15.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 16.7;testis cancer: 16.2" "Adrenal gland - Fibroblasts, Colon - Fibroblasts, Pituitary gland - Fibroblasts, Prostate - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015258, HPA065820" Enhanced Nucleoplasm NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 13 Nucleoplasm "HPA015258: , HPA065820: " "unprognostic (3.88e-2)" "unprognostic (3.22e-1)" "unprognostic (2.22e-1)" "unprognostic (3.02e-2)" "unprognostic (5.42e-2)" "unprognostic (3.61e-2)" "unprognostic (2.23e-1)" "unprognostic (5.42e-3)" "unprognostic (2.12e-2)" "unprognostic (1.98e-2)" "unprognostic (1.44e-3)" "potential prognostic favorable (9.59e-4)" "unprognostic (4.13e-2)" "unprognostic (2.87e-2)" "unprognostic (2.10e-2)" "unprognostic (3.16e-3)" "unprognostic (2.01e-1)" "unprognostic (1.78e-1)" "unprognostic (9.14e-2)" "unprognostic (6.69e-2)" "unprognostic (2.88e-1)" "unprognostic (2.40e-2)" "unprognostic (2.92e-1)" "unprognostic (1.68e-1)" "unprognostic (9.55e-2)" "unprognostic (1.19e-2)" "unprognostic (1.65e-1)" "unprognostic (6.88e-2)" "unprognostic (4.70e-2)" ZNF425 ENSG00000204947 "Zinc finger protein 425" Q6IV72 7 149102784-149126324 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Retinal ganglion cells: 46.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" HPA020087 Uncertain Supported Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 65: Brain - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 39: Non-specific - Transcription" "Cluster 65: Non-specific - Cell growth & division" 1 Nucleoplasm "HPA020087: " "unprognostic (1.14e-3)" "unprognostic (4.86e-2)" "unprognostic (3.65e-2)" "unprognostic (4.68e-1)" "validated prognostic unfavorable (9.21e-4)" "validated prognostic unfavorable (9.19e-4)" "unprognostic (2.51e-1)" "unprognostic (8.24e-2)" "unprognostic (2.25e-2)" "unprognostic (1.40e-2)" "unprognostic (4.69e-3)" "unprognostic (3.34e-1)" "unprognostic (1.79e-1)" "unprognostic (8.51e-2)" "unprognostic (7.01e-2)" "unprognostic (8.21e-2)" "unprognostic (1.21e-2)" "unprognostic (4.21e-2)" "unprognostic (1.76e-1)" "unprognostic (3.89e-3)" "unprognostic (6.50e-2)" "unprognostic (2.62e-1)" "unprognostic (2.96e-2)" "unprognostic (1.25e-1)" "unprognostic (2.55e-2)" "unprognostic (3.71e-2)" "unprognostic (1.51e-1)" "unprognostic (8.49e-2)" "unprognostic (7.53e-2)" ZNF426 MGC2663 ENSG00000130818 "Zinc finger protein 426" Q9BUY5 19 9523223-9538645 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 9 "Esophageal apical cells: 413.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" HPA029342 Approved Approved Nucleoplasm Yes No "Cluster 15: NK-cells - Unknown function" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 55: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 35 Nucleoplasm "HPA029342: " "unprognostic (4.64e-3)" "unprognostic (2.07e-1)" "unprognostic (9.55e-2)" "unprognostic (4.71e-2)" "unprognostic (3.94e-1)" "unprognostic (6.39e-2)" "unprognostic (1.39e-1)" "unprognostic (1.37e-1)" "potential prognostic favorable (9.20e-4)" "unprognostic (1.25e-2)" "validated prognostic favorable (8.42e-6)" "validated prognostic favorable (1.91e-4)" "potential prognostic favorable (6.50e-4)" "unprognostic (9.01e-2)" "unprognostic (2.42e-1)" "unprognostic (6.34e-2)" "unprognostic (1.41e-1)" "unprognostic (1.05e-1)" "unprognostic (3.32e-2)" "unprognostic (9.14e-2)" "unprognostic (2.15e-2)" "unprognostic (9.70e-2)" "unprognostic (4.89e-2)" "unprognostic (4.54e-2)" "potential prognostic favorable (1.07e-4)" "unprognostic (1.71e-3)" "unprognostic (6.00e-3)" "unprognostic (1.15e-1)" "unprognostic (2.76e-1)" "unprognostic (1.24e-1)" "unprognostic (1.31e-1)" ZNF428 "C19orf37, MGC51082, Zfp428" ENSG00000131116 "Zinc finger protein 428" Q96B54 19 43607224-43619629 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Undifferentiated spermatogonia: 296.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042596, HPA048072" Uncertain Approved Nucleoli,Mitochondria NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 78: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 35: RS4;11 - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 13 Mitochondria Nucleoli "HPA042596: , HPA048072: " "unprognostic (8.77e-3)" "unprognostic (5.68e-3)" "unprognostic (5.87e-2)" "unprognostic (2.01e-1)" "potential prognostic unfavorable (8.33e-4)" "unprognostic (4.99e-2)" "unprognostic (1.36e-1)" "unprognostic (6.96e-2)" "unprognostic (2.14e-1)" "unprognostic (1.50e-1)" "unprognostic (4.53e-3)" "unprognostic (6.64e-2)" "unprognostic (4.63e-3)" "unprognostic (1.09e-2)" "unprognostic (7.55e-3)" "unprognostic (1.60e-1)" "unprognostic (4.46e-1)" "unprognostic (1.34e-2)" "unprognostic (3.86e-2)" "unprognostic (3.80e-2)" "unprognostic (3.82e-1)" "potential prognostic favorable (1.16e-4)" "unprognostic (5.58e-2)" "unprognostic (2.42e-2)" "unprognostic (1.46e-1)" "unprognostic (7.18e-3)" "unprognostic (3.09e-2)" "unprognostic (2.83e-1)" "unprognostic (4.88e-2)" "unprognostic (2.05e-1)" "unprognostic (1.41e-2)" ZNF429 ENSG00000197013 "Zinc finger protein 429" Q86V71 19 21496682-21556270 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 5 "Neutrophils: 489.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells" HPA004139 Approved Nucleoplasm NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 61: Non-specific - Transcription" "Cluster 9: Non-specific - Receptor signaling" "Cluster 4: Non-specific - Transcription" "Cluster 29: Neutrophils - Innate immune cellular maintenance" Nucleoplasm "HPA004139: " "unprognostic (1.51e-2)" "unprognostic (3.85e-2)" "unprognostic (2.04e-1)" "unprognostic (1.27e-1)" "unprognostic (2.71e-1)" "potential prognostic favorable (3.52e-4)" "unprognostic (3.34e-2)" "unprognostic (3.29e-2)" "unprognostic (3.93e-1)" "unprognostic (1.77e-2)" "validated prognostic favorable (2.80e-4)" "validated prognostic favorable (1.39e-4)" "unprognostic (2.49e-3)" "unprognostic (2.32e-2)" "unprognostic (1.31e-1)" "unprognostic (3.48e-3)" "unprognostic (7.05e-2)" "unprognostic (7.10e-3)" "unprognostic (2.39e-1)" "potential prognostic favorable (8.40e-5)" "unprognostic (8.31e-2)" "unprognostic (2.17e-3)" "unprognostic (2.83e-1)" "unprognostic (5.68e-2)" "unprognostic (2.92e-3)" "unprognostic (3.35e-2)" "unprognostic (1.37e-1)" "unprognostic (4.98e-2)" "unprognostic (4.77e-2)" "unprognostic (1.19e-1)" "unprognostic (3.52e-2)" ZNF43 "HTF6, KOX27, ZNF39L1" ENSG00000198521 "Zinc finger protein 43" P17038 19 21804946-21852125 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells" HPA050271 Uncertain NA NA "Cluster 32: Basophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 29: Neutrophils - Innate immune cellular maintenance" "HPA050271: " "unprognostic (8.56e-2)" "unprognostic (1.59e-1)" "unprognostic (3.78e-2)" "unprognostic (3.93e-2)" "unprognostic (6.87e-2)" "potential prognostic favorable (4.92e-4)" "unprognostic (7.70e-2)" "unprognostic (1.21e-1)" "unprognostic (1.03e-3)" "potential prognostic unfavorable (4.14e-4)" "unprognostic (2.78e-3)" "unprognostic (1.49e-1)" "unprognostic (8.46e-2)" "unprognostic (5.32e-2)" "unprognostic (1.78e-3)" "potential prognostic favorable (2.85e-4)" "unprognostic (1.27e-1)" "unprognostic (1.04e-1)" "unprognostic (2.49e-1)" "unprognostic (4.01e-2)" "unprognostic (1.62e-1)" "unprognostic (9.43e-2)" "unprognostic (5.56e-3)" "unprognostic (1.65e-1)" "unprognostic (9.24e-2)" "unprognostic (6.91e-2)" "unprognostic (4.58e-3)" "unprognostic (9.26e-2)" "unprognostic (4.34e-2)" "unprognostic (2.86e-2)" "unprognostic (1.32e-1)" ZNF430 FLJ13659 ENSG00000118620 "Zinc finger protein 430" Q9H8G1 19 21020634-21060050 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 130.2;Ocular epithelial cells: 110.5;Urothelial cells: 172.5" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 6 "Uterine Corpus Endometrial Carcinoma (TCGA): 114.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skeletal muscle - Endothelial cells" HPA059135 Uncertain NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 61: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 4: Non-specific - Transcription" "Cluster 69: Urothelial cells - Basic cellular functions" 3 "HPA059135: " "unprognostic (1.88e-2)" "unprognostic (8.01e-2)" "unprognostic (9.85e-2)" "unprognostic (2.98e-2)" "unprognostic (1.05e-1)" "unprognostic (1.57e-2)" "unprognostic (2.10e-1)" "unprognostic (8.49e-2)" "unprognostic (2.35e-2)" "unprognostic (2.55e-2)" "unprognostic (2.83e-3)" "unprognostic (1.49e-2)" "unprognostic (2.02e-2)" "unprognostic (1.02e-1)" "unprognostic (2.24e-1)" "unprognostic (8.33e-2)" "unprognostic (7.65e-3)" "unprognostic (4.18e-2)" "unprognostic (8.83e-2)" "unprognostic (3.79e-2)" "unprognostic (1.81e-3)" "unprognostic (1.06e-1)" "potential prognostic unfavorable (7.53e-4)" "unprognostic (5.95e-3)" "unprognostic (7.75e-3)" "unprognostic (2.04e-3)" "unprognostic (4.66e-3)" "unprognostic (6.60e-2)" "unprognostic (2.93e-1)" "unprognostic (2.71e-2)" "unprognostic (1.51e-1)" ZNF431 KIAA1969 ENSG00000196705 "Zinc finger protein 431" Q8TF32 19 21142024-21196053 "Essential proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 346.8;Alveolar cells type 1: 257.9;Esophageal apical cells: 794.4;Sertoli cells: 516.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells" HPA059135 Uncertain NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 54: Non-specific - Ribosome" "Cluster 25: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 18: Adrenal cortex cells - Steroidogensis" "HPA059135: " "unprognostic (3.60e-1)" "unprognostic (4.72e-2)" "unprognostic (9.36e-2)" "unprognostic (7.40e-2)" "unprognostic (3.55e-1)" "unprognostic (8.04e-2)" "unprognostic (4.53e-2)" "unprognostic (3.75e-2)" "unprognostic (3.62e-1)" "potential prognostic unfavorable (7.45e-4)" "unprognostic (1.14e-1)" "unprognostic (8.47e-2)" "unprognostic (4.63e-1)" "unprognostic (1.78e-1)" "unprognostic (3.08e-2)" "unprognostic (4.92e-2)" "unprognostic (5.36e-2)" "unprognostic (9.67e-2)" "unprognostic (3.24e-2)" "unprognostic (6.94e-3)" "unprognostic (9.79e-2)" "potential prognostic unfavorable (1.06e-4)" "unprognostic (8.26e-2)" "validated prognostic favorable (4.75e-5)" "validated prognostic favorable (1.13e-4)" "potential prognostic unfavorable (7.35e-5)" "unprognostic (4.52e-1)" "unprognostic (4.88e-1)" "unprognostic (7.67e-2)" "unprognostic (4.63e-2)" ZNF432 KIAA0798 ENSG00000256087 "Zinc finger protein 432" O94892 19 52031378-52095738 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "HPA052082, HPA060274, HPA065606" Uncertain Enhanced Nucleoplasm NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 42: Retina - Visual perception" "Cluster 31: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 105: Non-specific - Mixed function" 3 Nucleoplasm "HPA052082: , HPA060274: , HPA065606: " "potential prognostic favorable (9.46e-4)" "unprognostic (8.35e-3)" "unprognostic (1.88e-1)" "unprognostic (9.59e-2)" "unprognostic (1.32e-1)" "unprognostic (1.97e-1)" "unprognostic (1.61e-2)" "unprognostic (2.67e-1)" "unprognostic (3.69e-3)" "unprognostic (4.84e-3)" "unprognostic (1.25e-1)" "unprognostic (1.04e-2)" "unprognostic (7.20e-2)" "unprognostic (8.75e-2)" "unprognostic (1.71e-1)" "unprognostic (5.12e-2)" "unprognostic (1.13e-1)" "unprognostic (5.16e-2)" "unprognostic (1.24e-1)" "unprognostic (1.52e-1)" "unprognostic (1.86e-1)" "unprognostic (8.30e-2)" "unprognostic (3.61e-3)" "unprognostic (1.81e-2)" "unprognostic (2.73e-3)" "unprognostic (2.54e-1)" "unprognostic (3.02e-2)" "unprognostic (8.27e-2)" "unprognostic (1.89e-1)" "unprognostic (3.52e-2)" "unprognostic (2.40e-1)" ZNF433 FLJ40981 ENSG00000197647 "Zinc finger protein 433" Q8N7K0 19 12014715-12035741 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 20.4" "Cell type enhanced" "Detected in many" "Early spermatids: 205.4;Late primary spermatocytes: 140.0;Late spermatids: 175.3;Oocytes: 46.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" HPA073724 Enhanced Approved "Nuclear bodies" "Intracellular and membrane" Transcription NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 72: Kidney - Transmembrane transport" "Cluster 35: Non-specific - DNA binding" "Cluster 4: Non-specific - Transcription" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 9 "Nuclear bodies" "HPA073724: " "unprognostic (2.92e-3)" "unprognostic (7.23e-2)" "unprognostic (2.41e-1)" "unprognostic (6.99e-2)" "unprognostic (4.73e-2)" "unprognostic (1.10e-1)" "unprognostic (2.76e-1)" "unprognostic (2.44e-1)" "unprognostic (6.52e-2)" "potential prognostic unfavorable (8.38e-4)" "validated prognostic favorable (3.43e-4)" "validated prognostic favorable (7.63e-6)" "potential prognostic favorable (2.75e-5)" "unprognostic (2.62e-1)" "unprognostic (1.10e-2)" "unprognostic (5.51e-2)" "unprognostic (4.51e-2)" "unprognostic (3.16e-1)" "unprognostic (7.47e-2)" "unprognostic (5.98e-2)" "unprognostic (7.02e-2)" "unprognostic (5.09e-2)" "unprognostic (1.41e-1)" "unprognostic (8.86e-3)" "unprognostic (6.67e-2)" "unprognostic (2.37e-2)" "unprognostic (4.24e-2)" "unprognostic (1.04e-1)" "unprognostic (5.09e-2)" "unprognostic (1.47e-2)" "unprognostic (2.22e-1)" ZNF436 "KIAA1710, Zfp46" ENSG00000125945 "Zinc finger protein 436" Q9C0F3 1 23359448-23369836 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 5.3;Bergmann glia: 8.8;Brain excitatory neurons: 5.5;Brain inhibitory neurons: 5.2;Choroid plexus epithelial cells: 7.0;Ependymal cells: 4.2;Loop of henle epithelial cells: 2.3;Microglia: 2.5;Oligodendrocyte progenitor cells: 5.0;Oligodendrocytes: 5.1;Other brain neurons: 4.4;Papillary tip epithelial cells: 5.3;Proximal tubule cells: 2.6;Renal collecting duct intercalated cells: 3.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043817 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 55: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 104: Brain endothelial cells - Blood brain barrier" 21 "Nucleoplasm, Cytosol" "HPA043817: " "unprognostic (2.04e-2)" "unprognostic (5.45e-2)" "unprognostic (2.66e-1)" "unprognostic (3.10e-2)" "unprognostic (1.04e-1)" "unprognostic (2.19e-2)" "unprognostic (2.32e-1)" "unprognostic (3.60e-1)" "unprognostic (4.22e-2)" "unprognostic (1.54e-2)" "potential prognostic favorable (4.27e-4)" "unprognostic (3.29e-3)" "unprognostic (4.44e-1)" "unprognostic (1.26e-1)" "unprognostic (1.14e-1)" "unprognostic (3.00e-2)" "unprognostic (3.91e-2)" "unprognostic (1.61e-1)" "unprognostic (8.21e-2)" "unprognostic (1.36e-2)" "unprognostic (4.14e-1)" "unprognostic (4.57e-1)" "unprognostic (2.92e-2)" "unprognostic (6.80e-2)" "unprognostic (2.68e-1)" "unprognostic (1.20e-1)" "unprognostic (1.82e-1)" "unprognostic (4.62e-2)" "unprognostic (5.14e-1)" "unprognostic (2.15e-1)" "unprognostic (1.20e-1)" ZNF438 bA330O11.1 ENSG00000183621 "Zinc finger protein 438" Q7Z4V0 10 30820207-31031937 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Neutrophils: 1433.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Endothelial cells, Prostate - Fibroblasts, Spleen - Neutrophils_2, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039843 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 16: Non-specific - Transcription" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 50 Nucleoplasm Cytosol "HPA039843: " "unprognostic (6.24e-3)" "unprognostic (1.58e-1)" "unprognostic (6.98e-2)" "unprognostic (2.09e-1)" "unprognostic (1.05e-1)" "unprognostic (7.29e-3)" "unprognostic (3.52e-1)" "potential prognostic favorable (2.04e-4)" "unprognostic (1.34e-2)" "unprognostic (8.77e-2)" "unprognostic (8.28e-3)" "unprognostic (1.82e-2)" "unprognostic (3.56e-1)" "unprognostic (1.37e-3)" "unprognostic (1.17e-2)" "unprognostic (6.64e-2)" "unprognostic (4.65e-3)" "unprognostic (1.30e-1)" "unprognostic (2.51e-1)" "unprognostic (4.18e-2)" "unprognostic (7.48e-2)" "unprognostic (1.46e-2)" "unprognostic (3.09e-1)" "unprognostic (2.56e-2)" "unprognostic (1.10e-2)" "unprognostic (8.08e-2)" "unprognostic (1.69e-1)" "unprognostic (1.03e-1)" "unprognostic (1.74e-1)" "unprognostic (4.45e-2)" "unprognostic (2.00e-1)" ZNF439 DKFZp571K0837 ENSG00000171291 "Zinc finger protein 439" Q8NDP4 19 11848726-11883750 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 24.1" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 10.1" "Spleen - B-cells (Spleen)" HPA047845 Approved Uncertain Nucleoplasm NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 25: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 24 Nucleoplasm "HPA047845: " "unprognostic (6.06e-3)" "unprognostic (2.74e-2)" "unprognostic (3.34e-1)" "unprognostic (1.30e-2)" "unprognostic (3.07e-2)" "unprognostic (1.21e-2)" "unprognostic (3.90e-2)" "unprognostic (4.60e-2)" "unprognostic (7.39e-2)" "unprognostic (2.72e-2)" "potential prognostic favorable (5.94e-4)" "unprognostic (4.84e-2)" "unprognostic (1.44e-3)" "unprognostic (3.52e-3)" "unprognostic (1.67e-1)" "unprognostic (1.03e-2)" "unprognostic (1.42e-1)" "unprognostic (1.01e-1)" "unprognostic (8.87e-3)" "unprognostic (1.49e-3)" "unprognostic (6.31e-2)" "unprognostic (1.26e-1)" "unprognostic (2.27e-1)" "unprognostic (2.37e-1)" "unprognostic (2.11e-1)" "unprognostic (2.50e-1)" "unprognostic (4.50e-2)" "unprognostic (2.34e-1)" "unprognostic (1.73e-1)" ZNF44 "KOX7, ZNF504, ZNF55, ZNF58" ENSG00000197857 "Zinc finger protein 44" P15621 19 12224686-12294883 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 231.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA003146 Supported Approved Nucleoplasm,Microtubules,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 25: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 1 Nucleoplasm "Microtubules, Cytosol" "HPA003146: " "unprognostic (2.47e-3)" "unprognostic (2.28e-1)" "unprognostic (9.65e-2)" "unprognostic (3.01e-2)" "unprognostic (2.35e-1)" "unprognostic (2.66e-1)" "unprognostic (1.52e-1)" "unprognostic (6.96e-2)" "unprognostic (3.95e-2)" "unprognostic (1.69e-1)" "unprognostic (1.87e-1)" "unprognostic (2.80e-3)" "unprognostic (2.23e-2)" "potential prognostic unfavorable (6.06e-4)" "unprognostic (3.09e-1)" "unprognostic (4.48e-3)" "unprognostic (6.30e-2)" "unprognostic (1.26e-1)" "unprognostic (9.65e-2)" "unprognostic (3.74e-2)" "unprognostic (1.09e-1)" "unprognostic (1.07e-2)" "unprognostic (3.26e-3)" "unprognostic (1.50e-2)" "unprognostic (2.14e-1)" "unprognostic (2.54e-2)" "unprognostic (4.30e-3)" "unprognostic (6.40e-2)" "unprognostic (1.57e-1)" "unprognostic (1.72e-1)" "unprognostic (4.28e-1)" ZNF440 FLJ37933 ENSG00000171295 "Zinc finger protein 440" Q8IYI8 19 11814273-11835216 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 153.3;Fallopian tube ciliated cells: 106.9;Medullary thymic epithelial cells: 112.8;Respiratory ciliated cells: 291.5;Urothelial cells: 155.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 12.5" "Lineage enriched" "Detected in all" 4 "granulocytes: 12.5" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" HPA047845 Approved Approved Nucleoplasm NA NA "Cluster 32: Basophils - Transcription" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 17: Choroid plexus - Cilium" "Cluster 4: Non-specific - Transcription" "Cluster 107: Ciliated cells - Cilia assembly & function" 30 Nucleoplasm "HPA047845: " "potential prognostic favorable (5.57e-4)" "unprognostic (1.22e-1)" "unprognostic (1.49e-1)" "unprognostic (3.80e-1)" "unprognostic (1.39e-1)" "unprognostic (2.31e-1)" "unprognostic (1.36e-1)" "unprognostic (7.55e-3)" "unprognostic (7.18e-3)" "unprognostic (2.75e-2)" "validated prognostic favorable (3.29e-4)" "validated prognostic favorable (7.72e-4)" "unprognostic (3.57e-2)" "unprognostic (5.37e-2)" "unprognostic (3.38e-1)" "unprognostic (1.13e-1)" "unprognostic (1.25e-1)" "unprognostic (1.41e-1)" "unprognostic (2.29e-1)" "unprognostic (1.97e-2)" "unprognostic (1.11e-1)" "unprognostic (3.48e-1)" "unprognostic (1.60e-2)" "potential prognostic unfavorable (8.20e-5)" "potential prognostic favorable (9.87e-4)" "unprognostic (9.40e-2)" "unprognostic (2.52e-2)" "unprognostic (1.25e-1)" "unprognostic (2.28e-1)" "unprognostic (7.93e-2)" "unprognostic (1.44e-1)" ZNF441 FLJ38637 ENSG00000197044 "Zinc finger protein 441" Q8N8Z8 19 11767000-11784078 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bergmann glia: 36.9;Myonuclei: 44.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" HPA063338 Approved "Nuclear speckles" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 65: Brain - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 7 "Nuclear speckles" "HPA063338: " "potential prognostic favorable (1.02e-4)" "unprognostic (2.78e-1)" "unprognostic (6.32e-2)" "unprognostic (2.11e-1)" "unprognostic (2.83e-1)" "unprognostic (2.08e-1)" "unprognostic (2.89e-1)" "unprognostic (1.30e-1)" "unprognostic (2.07e-1)" "potential prognostic favorable (9.09e-4)" "unprognostic (1.61e-3)" "unprognostic (3.06e-2)" "unprognostic (1.50e-1)" "unprognostic (1.35e-2)" "unprognostic (3.90e-3)" "unprognostic (2.65e-1)" "unprognostic (7.16e-2)" "unprognostic (3.83e-1)" "unprognostic (1.70e-2)" "unprognostic (1.27e-1)" "unprognostic (3.24e-3)" "unprognostic (1.13e-1)" "unprognostic (1.70e-2)" "unprognostic (3.56e-2)" "unprognostic (5.84e-2)" "unprognostic (1.16e-2)" "unprognostic (2.07e-1)" "unprognostic (5.46e-2)" "unprognostic (1.64e-1)" "unprognostic (2.50e-3)" ZNF442 FLJ14356 ENSG00000198342 "Zinc finger protein 442" Q9H7R0 19 12345944-12365905 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ovarian stromal cells: 16.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "HPA045738, HPA053407" Uncertain Approved "Nuclear membrane,Vesicles" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 94: Gonadal somatic cells - Mixed function" "Nuclear membrane" Vesicles "HPA045738: , HPA053407: " "unprognostic (1.24e-1)" "unprognostic (8.46e-2)" "unprognostic (3.58e-1)" "unprognostic (3.53e-2)" "unprognostic (6.39e-2)" "unprognostic (7.71e-2)" "unprognostic (1.69e-2)" "potential prognostic favorable (2.52e-4)" "unprognostic (4.33e-3)" "unprognostic (2.25e-3)" "unprognostic (4.76e-2)" "unprognostic (3.60e-2)" "unprognostic (3.41e-2)" "unprognostic (5.27e-3)" "unprognostic (7.33e-2)" "unprognostic (1.20e-2)" "unprognostic (2.18e-1)" "unprognostic (1.00e-1)" "unprognostic (4.96e-3)" ZNF443 ZK1 ENSG00000180855 "Zinc finger protein 443" Q9Y2A4 19 12429706-12441021 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 5.3;Bergmann glia: 2.8;Brain excitatory neurons: 2.5;Brain inhibitory neurons: 2.9;Choroid plexus epithelial cells: 1.5;Ependymal cells: 3.2;Microglia: 3.1;Oligodendrocyte progenitor cells: 2.4;Oligodendrocytes: 1.3;Other brain neurons: 2.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "HPA003150, HPA018683" Approved Approved "Nucleoplasm,Centriolar satellite" NA NA "Cluster 32: Basophils - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 4: Non-specific - Transcription" "Cluster 104: Brain endothelial cells - Blood brain barrier" 1 Nucleoplasm "Centriolar satellite" "HPA003150: , HPA018683: " "unprognostic (1.19e-2)" "potential prognostic unfavorable (3.90e-4)" "unprognostic (6.08e-2)" "unprognostic (2.62e-2)" "unprognostic (4.86e-2)" "unprognostic (1.20e-1)" "unprognostic (1.65e-1)" "unprognostic (1.97e-2)" "unprognostic (2.39e-2)" "unprognostic (5.55e-2)" "potential prognostic favorable (2.51e-5)" "unprognostic (1.44e-3)" "potential prognostic favorable (7.69e-4)" "unprognostic (1.54e-1)" "unprognostic (6.63e-3)" "unprognostic (1.14e-1)" "unprognostic (4.53e-3)" "unprognostic (7.97e-2)" "unprognostic (1.44e-2)" "unprognostic (1.66e-2)" "unprognostic (2.28e-1)" "unprognostic (1.24e-1)" "unprognostic (1.30e-1)" "unprognostic (6.73e-2)" "potential prognostic favorable (6.72e-4)" "unprognostic (1.82e-1)" "unprognostic (1.11e-2)" "unprognostic (1.31e-2)" "unprognostic (2.64e-1)" "unprognostic (1.83e-1)" "unprognostic (2.51e-1)" ZNF444 "EZF2, FLJ11137, ZSCAN17" ENSG00000167685 "Zinc finger protein 444" Q8N0Y2 19 56132599-56160893 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056895, HPA065203" Approved Enhanced Nucleoplasm,Nucleoli Yes No "Cluster 3: Non-specific - Nuclear processes" "Cluster 70: Non-specific - Protein processing" "Cluster 18: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 3 Nucleoplasm Nucleoli "HPA056895: , HPA065203: " "unprognostic (2.23e-3)" "unprognostic (3.15e-2)" "unprognostic (2.80e-2)" "unprognostic (2.19e-2)" "unprognostic (1.67e-1)" "unprognostic (7.46e-2)" "unprognostic (2.05e-1)" "unprognostic (1.13e-2)" "unprognostic (1.33e-1)" "unprognostic (7.89e-2)" "unprognostic (4.78e-2)" "unprognostic (9.68e-2)" "unprognostic (4.42e-2)" "unprognostic (1.98e-3)" "unprognostic (1.63e-1)" "unprognostic (1.53e-1)" "unprognostic (1.58e-1)" "unprognostic (1.41e-1)" "unprognostic (2.10e-1)" "unprognostic (3.80e-1)" "unprognostic (1.32e-1)" "unprognostic (7.42e-3)" "unprognostic (2.78e-1)" "unprognostic (4.88e-1)" "unprognostic (1.86e-1)" "unprognostic (1.15e-1)" "unprognostic (1.14e-1)" "unprognostic (2.05e-2)" "unprognostic (3.09e-1)" "unprognostic (7.35e-2)" "unprognostic (1.44e-1)" ZNF445 "ZKSCAN15, ZNF168, ZSCAN47" ENSG00000185219 "Zinc finger protein 445" P59923 3 44431705-44477670 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006678 Uncertain Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 5 Nucleoplasm "Mitochondria, Cytosol" "HPA006678: " "unprognostic (2.55e-2)" "unprognostic (1.44e-1)" "unprognostic (2.72e-2)" "unprognostic (8.36e-3)" "unprognostic (1.41e-1)" "unprognostic (9.95e-2)" "unprognostic (9.11e-2)" "unprognostic (3.34e-2)" "unprognostic (6.24e-3)" "unprognostic (5.24e-3)" "unprognostic (2.10e-3)" "potential prognostic favorable (6.86e-4)" "unprognostic (3.26e-1)" "unprognostic (1.91e-1)" "unprognostic (8.06e-2)" "unprognostic (2.85e-2)" "unprognostic (1.28e-1)" "unprognostic (7.06e-2)" "unprognostic (1.71e-1)" "unprognostic (2.84e-2)" "unprognostic (5.88e-2)" "unprognostic (8.71e-2)" "unprognostic (3.38e-2)" "unprognostic (7.98e-3)" "unprognostic (2.04e-3)" "unprognostic (2.22e-2)" "unprognostic (2.96e-1)" "unprognostic (1.16e-1)" "unprognostic (9.94e-3)" "unprognostic (7.38e-2)" ZNF446 "FLJ20626, ZKSCAN20, ZSCAN52" ENSG00000083838 "Zinc finger protein 446" Q9NWS9 19 58474017-58481230 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 31.9;Early primary spermatocytes: 46.3;Fallopian tube ciliated cells: 31.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052786, HPA078262" Uncertain Supported "Nuclear speckles" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 21: Testis - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 3: Early primary spermatocytes - Early meiosis" 31 "Nuclear speckles" "HPA052786: , HPA078262: " "unprognostic (4.74e-3)" "unprognostic (8.88e-2)" "unprognostic (1.19e-1)" "unprognostic (4.37e-2)" "unprognostic (9.40e-2)" "unprognostic (7.79e-2)" "unprognostic (7.60e-2)" "unprognostic (8.75e-2)" "unprognostic (1.76e-2)" "unprognostic (6.10e-2)" "unprognostic (1.09e-1)" "unprognostic (2.08e-1)" "unprognostic (1.44e-2)" "unprognostic (4.87e-3)" "unprognostic (1.17e-1)" "unprognostic (1.72e-1)" "unprognostic (1.42e-2)" "unprognostic (2.84e-1)" "unprognostic (2.81e-2)" "unprognostic (1.88e-1)" "unprognostic (7.11e-2)" "potential prognostic favorable (2.41e-5)" "unprognostic (1.81e-1)" "unprognostic (5.71e-2)" "unprognostic (4.43e-2)" "unprognostic (1.25e-1)" "unprognostic (2.84e-1)" "unprognostic (1.59e-1)" "unprognostic (4.34e-2)" "unprognostic (2.59e-1)" "potential prognostic favorable (5.62e-4)" ZNF449 "FLJ23614, ZSCAN19" ENSG00000173275 "Zinc finger protein 449" Q6P9G9 X 135344796-135363413 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 42.8;Myonuclei: 23.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018079 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 109: Neurons - Neuronal signaling" 4 "Nucleoplasm, Cytosol" "HPA018079: " "unprognostic (1.29e-1)" "unprognostic (3.47e-3)" "unprognostic (8.10e-2)" "unprognostic (9.78e-2)" "unprognostic (2.06e-2)" "unprognostic (6.93e-2)" "unprognostic (1.05e-1)" "unprognostic (1.84e-3)" "unprognostic (1.54e-1)" "unprognostic (1.67e-2)" "unprognostic (2.73e-1)" "unprognostic (8.72e-2)" "unprognostic (1.57e-1)" "unprognostic (5.73e-3)" "unprognostic (2.55e-1)" "unprognostic (7.92e-2)" "unprognostic (1.15e-1)" "unprognostic (2.17e-1)" "unprognostic (5.03e-2)" "unprognostic (1.86e-1)" "unprognostic (1.71e-1)" "unprognostic (3.78e-1)" "unprognostic (3.22e-3)" "unprognostic (6.38e-2)" "unprognostic (1.82e-2)" "unprognostic (5.59e-3)" "unprognostic (4.23e-2)" "unprognostic (1.31e-1)" "unprognostic (2.59e-1)" "unprognostic (4.72e-2)" "unprognostic (3.28e-1)" ZNF45 ZNF13 ENSG00000124459 "Zinc finger protein 45" Q02386 19 43912624-43935282 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 40.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038611, HPA075124" Uncertain Supported Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 3 Nucleoplasm "HPA038611: , HPA075124: " "potential prognostic favorable (3.86e-4)" "unprognostic (1.38e-1)" "unprognostic (5.61e-2)" "unprognostic (3.20e-2)" "unprognostic (1.97e-1)" "unprognostic (5.42e-2)" "unprognostic (1.22e-1)" "unprognostic (5.10e-3)" "unprognostic (9.14e-2)" "unprognostic (4.26e-2)" "validated prognostic favorable (6.70e-6)" "validated prognostic favorable (1.91e-4)" "unprognostic (1.75e-1)" "unprognostic (4.77e-2)" "unprognostic (2.51e-1)" "unprognostic (1.35e-2)" "unprognostic (4.56e-1)" "unprognostic (1.81e-2)" "unprognostic (3.08e-2)" "unprognostic (4.69e-1)" "unprognostic (2.06e-1)" "unprognostic (2.85e-3)" "unprognostic (1.86e-1)" "unprognostic (1.40e-2)" "unprognostic (5.88e-2)" "unprognostic (1.99e-1)" "unprognostic (4.63e-3)" "unprognostic (1.86e-1)" "unprognostic (3.87e-1)" "unprognostic (3.01e-2)" "unprognostic (1.52e-1)" ZNF451 "COASTER, dJ417I1.1, KIAA0576, KIAA1702, ZATT" ENSG00000112200 "Zinc finger protein 451" Q9Y4E5 6 57086844-57170305 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 66.3" "Cell type enhanced" "Detected in all" "Late spermatids: 660.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028838 Approved Nucleoplasm NA NA "Cluster 18: Non-specific - Translation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 18: Adrenal cortex cells - Steroidogensis" 14 Nucleoplasm "HPA028838: " "unprognostic (1.65e-1)" "unprognostic (9.07e-2)" "unprognostic (2.57e-1)" "unprognostic (1.03e-1)" "unprognostic (1.35e-1)" "unprognostic (2.53e-1)" "unprognostic (7.12e-2)" "unprognostic (4.31e-3)" "unprognostic (3.85e-2)" "unprognostic (1.03e-2)" "potential prognostic favorable (1.96e-4)" "unprognostic (6.60e-3)" "unprognostic (2.27e-2)" "unprognostic (1.81e-1)" "unprognostic (1.99e-1)" "unprognostic (6.02e-2)" "unprognostic (4.12e-1)" "unprognostic (1.64e-1)" "unprognostic (5.14e-2)" "unprognostic (1.09e-1)" "unprognostic (2.44e-1)" "unprognostic (1.45e-1)" "unprognostic (3.04e-3)" "unprognostic (1.59e-1)" "unprognostic (1.29e-3)" "unprognostic (3.52e-2)" "unprognostic (9.92e-3)" "unprognostic (2.80e-1)" "unprognostic (3.15e-1)" "unprognostic (1.58e-2)" "unprognostic (2.37e-1)" ZNF454 FLJ37444 ENSG00000178187 "Zinc finger protein 454" Q8N9F8 5 178941191-178966433 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 28.9;Lactotrophs: 22.5;Retinal bipolar cells: 21.6;Somatotrophs: 21.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 1.9;testis cancer: 1.5" "Skin - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024556 Uncertain NA NA "Cluster 65: Brain - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "HPA024556: " "unprognostic (9.53e-2)" "unprognostic (1.97e-1)" "unprognostic (2.01e-2)" "unprognostic (8.07e-2)" "unprognostic (1.44e-1)" "unprognostic (1.32e-1)" "unprognostic (3.83e-2)" "unprognostic (1.01e-1)" "unprognostic (1.55e-1)" "unprognostic (3.87e-2)" ZNF460 "HZF8, ZNF272" ENSG00000197714 "Zinc finger protein 460" Q14592 19 57280051-57294069 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 94.3;Epicardial cells: 84.1;Medullary thymic epithelial cells: 48.0;Plasma cells: 54.6" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Stomach Adenocarcinoma (TCGA): 6.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "HPA053004, HPA066506" Uncertain Approved Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 15: Bone marrow - Innate immune response" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 78: Plasma cells - Antibody production & ER-stress response" 22 Nucleoplasm "HPA053004: , HPA066506: " "unprognostic (6.42e-3)" "unprognostic (2.00e-1)" "unprognostic (1.20e-1)" "unprognostic (4.06e-2)" "unprognostic (2.10e-2)" "unprognostic (6.30e-2)" "unprognostic (2.20e-2)" "unprognostic (4.84e-2)" "unprognostic (3.00e-1)" "unprognostic (6.07e-3)" "unprognostic (2.86e-3)" "potential prognostic favorable (1.66e-4)" "unprognostic (9.25e-2)" "unprognostic (3.40e-1)" "unprognostic (2.73e-2)" "unprognostic (2.30e-1)" "unprognostic (3.14e-2)" "unprognostic (2.09e-1)" "unprognostic (3.71e-3)" "unprognostic (9.49e-2)" "potential prognostic favorable (3.60e-4)" "unprognostic (3.23e-1)" "unprognostic (1.61e-1)" "unprognostic (2.69e-1)" ZNF461 "GIOT-1, MGC33911" ENSG00000197808 "Zinc finger protein 461" Q8TAF7 19 36636618-36666853 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 49.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" HPA021139 Uncertain Approved "Nucleoplasm,Nucleoli,Golgi apparatus" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 65: Brain - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" 1 "Golgi apparatus" "Nucleoplasm, Nucleoli" "HPA021139: " "unprognostic (6.34e-3)" "unprognostic (1.82e-1)" "unprognostic (2.24e-2)" "unprognostic (1.29e-1)" "unprognostic (2.91e-1)" "unprognostic (1.79e-3)" "unprognostic (1.04e-1)" "unprognostic (1.81e-1)" "unprognostic (3.79e-2)" "unprognostic (8.97e-2)" "potential prognostic favorable (3.47e-5)" "unprognostic (1.36e-2)" "unprognostic (4.17e-2)" "unprognostic (3.78e-1)" "unprognostic (8.56e-2)" "unprognostic (7.36e-2)" "unprognostic (2.22e-1)" "unprognostic (9.36e-2)" "unprognostic (3.28e-1)" "unprognostic (1.44e-1)" "unprognostic (3.37e-2)" "potential prognostic favorable (8.75e-4)" "unprognostic (1.97e-2)" "unprognostic (4.45e-2)" "unprognostic (1.94e-1)" "unprognostic (3.56e-3)" "unprognostic (1.21e-2)" "unprognostic (3.13e-2)" "unprognostic (2.40e-1)" "unprognostic (1.80e-1)" "unprognostic (2.52e-1)" ZNF462 "DKFZP762N2316, KIAA1803, Zfp462" ENSG00000148143 "Zinc finger protein 462" Q96JM2 9 106863166-107013634 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bergmann glia: 320.8;Oligodendrocyte progenitor cells: 730.3" "Cell type enhanced" "Detected in all" "oligodendrocyte precursor cell: 857.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Vascular endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022283 Uncertain Supported Nucleoplasm NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 19: Astrocytes - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 10 Nucleoplasm "HPA022283: " "unprognostic (3.89e-2)" "unprognostic (6.05e-2)" "unprognostic (2.48e-1)" "unprognostic (9.48e-2)" "unprognostic (1.67e-1)" "unprognostic (6.46e-2)" "unprognostic (1.28e-1)" "unprognostic (2.68e-3)" "unprognostic (1.26e-1)" "unprognostic (3.31e-1)" "validated prognostic favorable (3.96e-6)" "validated prognostic favorable (5.16e-7)" "unprognostic (1.76e-1)" "unprognostic (2.74e-1)" "unprognostic (1.78e-1)" "unprognostic (2.33e-1)" "unprognostic (4.12e-3)" "unprognostic (1.12e-3)" "unprognostic (1.47e-1)" "unprognostic (1.12e-1)" "unprognostic (1.86e-1)" "unprognostic (3.01e-1)" "unprognostic (2.56e-1)" "unprognostic (1.12e-1)" "unprognostic (7.14e-2)" "unprognostic (7.49e-2)" "unprognostic (1.35e-1)" "unprognostic (6.28e-2)" "unprognostic (5.42e-2)" ZNF467 "EZI, Zfp467" ENSG00000181444 "Zinc finger protein 467" Q7Z7K2 7 149764182-149773588 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "cDC: 31.6;Hofbauer cells: 33.1;Kupffer cells: 55.3;Lymphatic endothelial cells: 51.6;Megakaryocytes: 37.1;monocytes: 46.8;Müller glia: 68.2;Neutrophils: 133.9;Retinal bipolar cells: 52.0;Retinal pigment epithelial cells: 34.1" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 23.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "neutrophil: 48.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 48.9" "Cancer enhanced" "Detected in many" "Rhabdoid: 17.8" "Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042907 Uncertain Approved Mitochondria NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 3 Mitochondria "HPA042907: " "unprognostic (1.93e-1)" "unprognostic (3.73e-1)" "unprognostic (5.56e-2)" "unprognostic (1.08e-1)" "unprognostic (1.64e-2)" "unprognostic (9.58e-2)" "unprognostic (6.96e-2)" "unprognostic (6.98e-2)" "unprognostic (1.99e-1)" "unprognostic (7.12e-2)" "unprognostic (1.06e-1)" "unprognostic (8.93e-2)" "unprognostic (2.89e-1)" "unprognostic (2.16e-1)" "unprognostic (2.03e-1)" "unprognostic (1.38e-1)" "unprognostic (2.96e-1)" "unprognostic (4.96e-2)" "unprognostic (1.25e-2)" "unprognostic (1.45e-1)" "unprognostic (3.33e-2)" "unprognostic (3.10e-3)" "unprognostic (1.99e-3)" "unprognostic (2.07e-1)" "unprognostic (8.06e-3)" "unprognostic (3.18e-1)" "unprognostic (9.82e-2)" "unprognostic (4.14e-2)" "unprognostic (1.20e-1)" "unprognostic (1.35e-1)" "unprognostic (2.33e-2)" ZNF468 ENSG00000204604 "Zinc finger protein 468" Q5VIY5 19 52838010-52857649 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Conjunctival goblet cells: 1.9;Epididymal clear cells: 2.0;Parietal cells: 1.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Macrophages, Testis - Spermatogonia" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 1 "potential prognostic favorable (5.10e-4)" "unprognostic (1.37e-3)" "unprognostic (2.28e-1)" "unprognostic (2.87e-1)" "unprognostic (6.41e-3)" "unprognostic (1.31e-1)" "unprognostic (1.62e-1)" "unprognostic (2.65e-1)" "unprognostic (4.29e-2)" "unprognostic (6.48e-2)" "potential prognostic favorable (1.63e-6)" "unprognostic (6.93e-2)" "unprognostic (1.32e-1)" "unprognostic (6.01e-3)" "unprognostic (1.86e-2)" "unprognostic (4.91e-2)" "unprognostic (2.21e-2)" "unprognostic (2.06e-2)" "unprognostic (9.09e-2)" "unprognostic (2.13e-1)" "potential prognostic unfavorable (6.05e-4)" "unprognostic (3.85e-1)" "unprognostic (1.65e-1)" "unprognostic (1.59e-3)" "unprognostic (3.29e-1)" "unprognostic (5.06e-2)" "unprognostic (6.61e-2)" "unprognostic (1.27e-1)" "unprognostic (1.78e-2)" "unprognostic (1.08e-1)" "unprognostic (1.34e-1)" ZNF469 "KIAA1858, Zfp469" ENSG00000225614 "Zinc finger protein 469" Q96JG9 16 88382959-88440757 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "ovary: 2.1" "Cell type enhanced" "Detected in many" "cDC: 8.5;Fibroblasts: 6.2;Hofbauer cells: 7.3;Macrophages: 8.2;Microglia: 8.9;Oligodendrocyte progenitor cells: 27.4;Oligodendrocytes: 20.3;Respiratory ciliated cells: 7.3" "Group enriched" "Detected in many" 5 "committed oligodendrocyte precursor: 98.2;oligodendrocyte precursor cell: 31.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 4.6" "Adipose subcutaneous - Adipose progenitor cells, Skin - Fibroblasts_1, Skin - Fibroblasts_2, Testis - Spermatogonia, Thyroid gland - Macrophages" "Not detected" "Not detected" HPA077792 Approved "Nucleoplasm,Cell Junctions" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" Nucleoplasm "Cell Junctions" "HPA077792: " "unprognostic (9.58e-2)" "unprognostic (2.09e-1)" "unprognostic (6.46e-2)" "unprognostic (3.57e-2)" "unprognostic (2.95e-1)" "unprognostic (2.21e-1)" "unprognostic (1.63e-1)" "unprognostic (3.02e-1)" "unprognostic (4.39e-2)" "unprognostic (2.63e-2)" "unprognostic (1.33e-1)" "unprognostic (4.34e-2)" "unprognostic (2.62e-1)" "unprognostic (6.83e-3)" "unprognostic (9.83e-2)" "unprognostic (2.71e-3)" "unprognostic (3.71e-2)" ZNF470 "CZF-1, FLJ26175" ENSG00000197016 "Zinc finger protein 470" Q6ECI4 19 56567468-56588911 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" HPA029000 Uncertain Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 6: Non-specific - Immune response" "Cluster 4: Non-specific - Transcription" "Cluster 79: Photoreceptor cells - Phototransduction" "Nucleoplasm, Nuclear bodies" "HPA029000: " "unprognostic (4.12e-3)" "unprognostic (3.64e-2)" "unprognostic (1.59e-1)" "unprognostic (8.49e-2)" "unprognostic (7.18e-2)" "unprognostic (1.02e-2)" "unprognostic (1.67e-1)" "unprognostic (2.90e-2)" "unprognostic (1.30e-1)" "validated prognostic favorable (9.70e-4)" "validated prognostic favorable (2.33e-4)" "unprognostic (2.11e-3)" "unprognostic (2.72e-2)" "unprognostic (3.23e-1)" "unprognostic (1.16e-2)" "unprognostic (4.20e-2)" "unprognostic (1.97e-2)" "unprognostic (4.10e-1)" "unprognostic (2.40e-1)" "unprognostic (4.01e-1)" "unprognostic (1.44e-3)" "unprognostic (2.15e-2)" "unprognostic (1.02e-1)" "unprognostic (4.79e-2)" "unprognostic (3.45e-1)" "unprognostic (4.45e-3)" "unprognostic (1.22e-2)" "unprognostic (2.54e-1)" "unprognostic (1.43e-2)" "unprognostic (1.84e-1)" ZNF471 "KIAA1396, Z1971, Zfp78" ENSG00000196263 "Zinc finger protein 471" Q9BX82 19 56507850-56530221 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 43.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" HPA066695 Uncertain Supported Nucleoplasm NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 65: Brain - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 4: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 1 Nucleoplasm "HPA066695: " "unprognostic (2.09e-2)" "unprognostic (4.55e-1)" "unprognostic (2.92e-1)" "unprognostic (2.58e-1)" "unprognostic (2.70e-2)" "unprognostic (1.10e-1)" "unprognostic (3.61e-2)" "unprognostic (9.15e-2)" "unprognostic (2.06e-2)" "potential prognostic favorable (2.20e-6)" "unprognostic (1.94e-3)" "unprognostic (2.23e-1)" "unprognostic (3.78e-2)" "unprognostic (4.93e-2)" "unprognostic (2.19e-1)" "unprognostic (1.95e-1)" "unprognostic (2.53e-1)" "unprognostic (3.12e-1)" "unprognostic (1.43e-3)" "unprognostic (2.31e-2)" "unprognostic (6.67e-3)" "unprognostic (2.60e-3)" "unprognostic (9.50e-3)" "unprognostic (1.03e-1)" "unprognostic (1.61e-1)" "unprognostic (3.51e-2)" "unprognostic (1.61e-1)" ZNF473 "DKFZP434N043, HZFP100, KIAA1141" ENSG00000142528 "Zinc finger protein 473" Q8WTR7 19 50025714-50053414 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "testis: 39.6" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 48.9;Early spermatids: 92.7;Late primary spermatocytes: 123.4;Respiratory ciliated cells: 57.1" "Cell type enhanced" "Detected in all" "ependymal cell: 24.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Spleen - Endothelial cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA004191, HPA073309" Approved Supported Nucleoplasm NA NA "Cluster 32: Basophils - Transcription" "Cluster 47: Testis - Mixed function" "Cluster 46: Brainstem - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 17 Nucleoplasm "HPA004191: , HPA073309: " "unprognostic (6.67e-2)" "unprognostic (1.23e-2)" "unprognostic (1.35e-1)" "unprognostic (3.05e-2)" "unprognostic (1.37e-1)" "potential prognostic unfavorable (5.68e-4)" "unprognostic (2.14e-1)" "unprognostic (1.20e-1)" "unprognostic (5.69e-3)" "unprognostic (8.62e-3)" "potential prognostic favorable (6.06e-7)" "unprognostic (2.52e-2)" "unprognostic (5.65e-2)" "unprognostic (3.71e-3)" "unprognostic (9.80e-2)" "unprognostic (1.11e-1)" "unprognostic (1.04e-1)" "unprognostic (8.19e-2)" "unprognostic (1.14e-1)" "unprognostic (1.86e-1)" "unprognostic (1.07e-1)" "unprognostic (8.22e-2)" "unprognostic (2.41e-2)" "unprognostic (7.29e-3)" "unprognostic (5.83e-2)" "unprognostic (2.03e-1)" "unprognostic (2.46e-2)" "unprognostic (2.02e-1)" "unprognostic (3.58e-2)" "unprognostic (2.77e-1)" "unprognostic (2.03e-1)" ZNF474 "4933409D10Rik, FLJ32921" ENSG00000164185 "Zinc finger protein 474" Q6S9Z5 5 122129546-122182658 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "choroid plexus: 7.6;fallopian tube: 16.2;testis: 8.6" "Cell type enriched" "Detected in some" 5 "Late spermatids: 588.5" "Group enriched" "Detected in some" 48 "choroid plexus epithelial cell: 2.5;ependymal cell: 7.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" HPA036594 Approved "Nucleoplasm,Nuclear membrane,Plasma membrane" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 72: Neuronal - Signal transduction" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 18 "Nuclear membrane" "Nucleoplasm, Plasma membrane" "HPA036594: " "unprognostic (1.63e-1)" "unprognostic (3.81e-1)" "unprognostic (9.43e-2)" "unprognostic (4.08e-3)" "unprognostic (1.60e-1)" "unprognostic (2.23e-3)" "unprognostic (5.98e-2)" "unprognostic (9.94e-3)" ZNF479 KR19 ENSG00000185177 "Zinc finger protein 479" Q96JC4 7 57117676-57139864 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 20 "testis: 2.6" "Group enriched" "Detected in some" 5 "Early spermatids: 115.3;Late primary spermatocytes: 37.4;Late spermatids: 35.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 48: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 5 ZNF48 "DKFZp762K013, FLJ31751, MGC43952, ZNF553" ENSG00000180035 "Zinc finger protein 48" Q96MX3 16 30378106-30400108 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023806 Uncertain Approved Mitochondria No No "Cluster 27: T-cells - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 9: T-cells - Adaptive immunity: Regulation" 21 Mitochondria "HPA023806: " "unprognostic (1.62e-2)" "unprognostic (3.49e-1)" "unprognostic (7.16e-2)" "unprognostic (3.59e-2)" "unprognostic (2.10e-2)" "unprognostic (2.18e-1)" "unprognostic (3.22e-2)" "potential prognostic favorable (6.16e-6)" "unprognostic (1.55e-1)" "unprognostic (7.99e-2)" "potential prognostic favorable (8.63e-5)" "unprognostic (2.30e-2)" "unprognostic (2.61e-3)" "unprognostic (2.12e-3)" "unprognostic (1.06e-2)" "unprognostic (2.34e-1)" "unprognostic (3.17e-2)" "unprognostic (2.00e-1)" "unprognostic (2.19e-2)" "unprognostic (1.61e-1)" "unprognostic (4.63e-2)" "potential prognostic favorable (5.03e-4)" "unprognostic (4.81e-1)" "unprognostic (6.90e-2)" "unprognostic (4.11e-3)" "unprognostic (4.37e-1)" "unprognostic (2.63e-1)" "unprognostic (1.28e-1)" "unprognostic (2.67e-1)" "unprognostic (9.47e-2)" "unprognostic (3.74e-3)" ZNF480 MGC32104 ENSG00000198464 "Zinc finger protein 480" Q8WV37 19 52297169-52325922 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA042218 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 52: Non-specific - Cellular respiration" "Cluster 9: Non-specific - Receptor signaling" "Cluster 4: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 2 Nucleoplasm Cytosol "HPA042218: " "unprognostic (3.59e-1)" "unprognostic (2.77e-1)" "unprognostic (2.25e-1)" "unprognostic (2.47e-2)" "unprognostic (4.88e-2)" "unprognostic (1.27e-1)" "unprognostic (2.67e-1)" "unprognostic (1.90e-1)" "unprognostic (8.28e-2)" "unprognostic (1.02e-3)" "unprognostic (1.65e-1)" "unprognostic (4.92e-2)" "unprognostic (1.23e-1)" "potential prognostic unfavorable (8.28e-4)" "unprognostic (2.02e-1)" "unprognostic (6.76e-2)" "unprognostic (1.69e-1)" "unprognostic (3.84e-1)" "unprognostic (1.13e-1)" "unprognostic (1.20e-1)" "unprognostic (2.07e-1)" "potential prognostic unfavorable (5.45e-4)" "unprognostic (3.83e-1)" "unprognostic (2.15e-1)" "unprognostic (4.26e-2)" "unprognostic (2.37e-1)" "potential prognostic unfavorable (6.01e-7)" "potential prognostic unfavorable (2.99e-4)" "unprognostic (2.84e-1)" "unprognostic (2.08e-1)" "unprognostic (1.59e-1)" ZNF483 "KIAA1962, ZKSCAN16, ZSCAN48" ENSG00000173258 "Zinc finger protein 483" Q8TF39 9 111525159-111577844 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.7" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 192.6;Brain inhibitory neurons: 211.0;Corticotrophs: 222.3;Lactotrophs: 313.3;Other brain neurons: 227.3;Pituicytes/FSCs: 339.5;Somatotrophs: 286.5;Thyrotrophs: 277.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 11.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055041 Approved Nucleoli NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 65: Brain - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 15 Nucleoli "HPA055041: " "unprognostic (9.40e-2)" "unprognostic (6.75e-2)" "unprognostic (1.47e-2)" "unprognostic (1.07e-1)" "unprognostic (2.03e-2)" "unprognostic (6.72e-2)" "unprognostic (2.28e-2)" "unprognostic (9.25e-2)" "unprognostic (2.19e-2)" "potential prognostic favorable (1.24e-6)" "unprognostic (1.47e-2)" "potential prognostic favorable (3.72e-4)" "unprognostic (1.44e-1)" "unprognostic (1.20e-1)" "unprognostic (1.53e-2)" "unprognostic (8.76e-2)" "unprognostic (3.07e-2)" "unprognostic (2.77e-1)" "unprognostic (1.79e-1)" "unprognostic (1.29e-2)" "unprognostic (1.51e-1)" "unprognostic (1.75e-1)" "unprognostic (1.67e-1)" "unprognostic (1.19e-1)" "unprognostic (8.80e-2)" ZNF484 "BA526D8.4, FLJ33884" ENSG00000127081 "Zinc finger protein 484" Q5JVG2 9 92844182-92878038 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028973 Uncertain Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 65: Brain - Transcription" "Cluster 2: Neurons - Nucleosome" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Transcription" Nucleoplasm "Nuclear membrane, Cytosol" "HPA028973: " "unprognostic (1.40e-1)" "unprognostic (1.12e-1)" "unprognostic (2.01e-1)" "unprognostic (5.07e-2)" "unprognostic (4.45e-3)" "potential prognostic unfavorable (6.85e-5)" "unprognostic (1.91e-1)" "unprognostic (2.45e-2)" "unprognostic (3.28e-1)" "unprognostic (9.05e-2)" "validated prognostic favorable (2.31e-6)" "validated prognostic favorable (1.07e-4)" "unprognostic (4.84e-2)" "unprognostic (2.32e-2)" "unprognostic (1.69e-1)" "unprognostic (5.44e-2)" "unprognostic (2.67e-2)" "unprognostic (6.81e-2)" "unprognostic (4.17e-2)" "unprognostic (4.73e-3)" "unprognostic (2.93e-1)" "unprognostic (8.76e-2)" "unprognostic (4.51e-2)" "unprognostic (5.81e-2)" "unprognostic (8.94e-2)" "unprognostic (1.08e-2)" "unprognostic (1.81e-1)" "unprognostic (1.42e-1)" "unprognostic (5.48e-2)" "unprognostic (4.53e-1)" ZNF485 ENSG00000198298 "Zinc finger protein 485" Q8NCK3 10 43606419-43617904 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 12.9;Late primary spermatocytes: 32.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" HPA059356 Uncertain NA NA "Cluster 24: Non-specific - Transcription" "Cluster 39: Testis - Nuclear processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 6 "HPA059356: " "unprognostic (2.84e-1)" "potential prognostic unfavorable (1.32e-4)" "unprognostic (9.93e-2)" "unprognostic (4.92e-2)" "unprognostic (1.04e-1)" "unprognostic (2.77e-1)" "unprognostic (2.58e-2)" "potential prognostic favorable (1.71e-4)" "unprognostic (3.52e-1)" "unprognostic (1.35e-1)" "unprognostic (6.63e-2)" "unprognostic (3.35e-2)" "potential prognostic unfavorable (2.87e-4)" "unprognostic (8.72e-3)" "unprognostic (6.47e-2)" "unprognostic (6.37e-3)" "unprognostic (3.74e-1)" "unprognostic (3.24e-1)" "unprognostic (2.52e-2)" "unprognostic (3.08e-1)" "unprognostic (4.58e-2)" "unprognostic (5.53e-1)" "unprognostic (4.01e-3)" "unprognostic (4.34e-3)" "unprognostic (2.07e-2)" "unprognostic (2.66e-1)" "unprognostic (2.37e-2)" "unprognostic (1.58e-1)" "unprognostic (9.58e-3)" "unprognostic (3.61e-1)" ZNF486 "KRBO2, MGC2396" ENSG00000256229 "Zinc finger protein 486" Q96H40 19 20167214-20200488 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 32.4" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 51.2;Fallopian tube ciliated cells: 34.2;Loop of henle epithelial cells: 38.0;Papillary tip epithelial cells: 101.6;Prostatic hillock cells: 52.5;Renal collecting duct principal cells: 39.5;Renal connecting tubule cells: 50.0;Urothelial cells: 43.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 42.0;Thyroid Carcinoma (TCGA): 39.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 9.6" "Lineage enriched" "Detected in many" 4 "granulocytes: 9.6" "Cancer enhanced" "Detected in many" "testis cancer: 18.5" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 33: Thyroid gland - Tissue development" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 69: Urothelial cells - Basic cellular functions" "unprognostic (3.94e-3)" "unprognostic (1.78e-3)" "unprognostic (4.87e-2)" "unprognostic (3.03e-3)" "unprognostic (1.57e-1)" "unprognostic (6.38e-2)" "unprognostic (4.83e-2)" "unprognostic (1.38e-1)" "unprognostic (9.21e-3)" "unprognostic (6.10e-3)" "potential prognostic favorable (2.32e-4)" "unprognostic (8.13e-2)" "unprognostic (1.19e-1)" "unprognostic (3.38e-1)" "unprognostic (1.06e-2)" "unprognostic (1.77e-1)" "unprognostic (9.58e-2)" "unprognostic (2.47e-1)" "unprognostic (6.65e-3)" "unprognostic (3.07e-3)" "unprognostic (1.18e-1)" "unprognostic (5.79e-2)" "unprognostic (5.22e-2)" "unprognostic (1.36e-2)" "unprognostic (2.28e-2)" "unprognostic (1.39e-3)" "unprognostic (1.24e-1)" "unprognostic (2.54e-1)" "unprognostic (1.81e-1)" "unprognostic (2.78e-1)" ZNF487 "KRBO1, ZNF487P" ENSG00000243660 "Zinc finger protein 487" 10 43436841-43483181 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 26.2" "Cell type enhanced" "Detected in many" "Early spermatids: 235.8;Ependymal cells: 122.8;Late spermatids: 440.5;Respiratory ciliated cells: 146.0" "Cell type enhanced" "Detected in all" "ependymal cell: 131.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" HPA037820 Approved "Nucleoplasm,Nuclear membrane,Cytosol" Yes No "Cluster 28: Neutrophils - Unknown function" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 52: Non-specific - Mitochondria" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" "Nuclear membrane" "Nucleoplasm, Cytosol" "HPA037820: " "unprognostic (3.98e-2)" "unprognostic (1.47e-3)" "unprognostic (3.68e-2)" "unprognostic (3.04e-3)" "unprognostic (1.90e-1)" "unprognostic (7.48e-2)" "unprognostic (9.45e-2)" "unprognostic (6.93e-2)" "unprognostic (2.64e-3)" "unprognostic (4.58e-2)" "unprognostic (1.09e-1)" "unprognostic (3.54e-2)" "unprognostic (1.24e-1)" "unprognostic (2.21e-1)" "unprognostic (6.31e-2)" "unprognostic (1.10e-1)" "unprognostic (1.89e-2)" "unprognostic (6.03e-2)" "unprognostic (5.49e-2)" "unprognostic (2.36e-2)" "unprognostic (3.86e-1)" "unprognostic (4.53e-2)" "unprognostic (8.24e-2)" "unprognostic (5.24e-2)" "unprognostic (8.59e-3)" "unprognostic (2.72e-2)" "unprognostic (1.81e-1)" "unprognostic (5.87e-2)" "unprognostic (4.90e-3)" "unprognostic (1.99e-1)" ZNF488 FLJ32104 ENSG00000265763 "Zinc finger protein 488" Q96MN9 10 47365496-47384293 "Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "brain: 61.2;intestine: 21.1" "Cell type enhanced" "Detected in some" "Breast secretory cells: 6.9;Corticotrophs: 10.4;Cytotrophoblasts: 7.7;Enterocytes: 25.8;Migrating cytotrophoblasts: 7.1;Oligodendrocyte progenitor cells: 14.2;Oligodendrocytes: 41.0;Retinal amacrine cells: 13.1;Syncytiotrophoblasts: 42.9" "Group enriched" "Detected in many" 4 "committed oligodendrocyte precursor: 67.1;hippocampal dentate gyrus: 17.9;oligodendrocyte: 45.9;oligodendrocyte precursor cell: 18.0" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 8.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Minor salivary gland basal cells, Skeletal muscle - Fibroblasts, Stomach - Mitotic cells (Stomach), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035957, HPA035958" Supported Nucleoplasm,Cytosol NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 17 "Nucleoplasm, Cytosol" "HPA035957: , HPA035958: " "unprognostic (4.26e-1)" "unprognostic (1.95e-1)" "unprognostic (2.33e-2)" "unprognostic (7.61e-2)" "unprognostic (2.98e-1)" "unprognostic (1.40e-1)" "unprognostic (1.13e-1)" "unprognostic (1.59e-1)" "unprognostic (1.67e-1)" "potential prognostic unfavorable (1.70e-6)" "unprognostic (2.65e-2)" "unprognostic (2.23e-2)" "unprognostic (1.93e-1)" "unprognostic (2.13e-1)" ZNF490 KIAA1198 ENSG00000188033 "Zinc finger protein 490" Q9ULM2 19 12576100-12640098 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 210.3;Epicardial cells: 129.6" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 5 "Testicular Germ Cell Tumor (TCGA): 19.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" HPA005576 Uncertain NA NA "Cluster 32: Basophils - Transcription" "Cluster 22: Epididymis - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 23: Non-specific - Transcription" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 27 "HPA005576: " "unprognostic (1.37e-1)" "unprognostic (1.45e-2)" "unprognostic (1.28e-1)" "unprognostic (3.38e-1)" "unprognostic (6.63e-2)" "unprognostic (3.56e-1)" "unprognostic (4.56e-2)" "unprognostic (1.54e-1)" "unprognostic (8.30e-3)" "unprognostic (3.63e-2)" "unprognostic (1.67e-2)" "unprognostic (1.35e-1)" "unprognostic (2.59e-3)" "potential prognostic unfavorable (2.95e-4)" "unprognostic (1.27e-1)" "unprognostic (1.58e-2)" "unprognostic (5.26e-2)" "unprognostic (2.22e-2)" "unprognostic (1.62e-2)" "unprognostic (2.03e-2)" "unprognostic (4.91e-3)" "unprognostic (6.20e-2)" "unprognostic (2.37e-2)" "unprognostic (1.54e-2)" "unprognostic (5.24e-2)" "unprognostic (3.14e-1)" "unprognostic (1.07e-2)" "unprognostic (2.65e-1)" "unprognostic (4.82e-2)" "unprognostic (1.93e-1)" ZNF491 FLJ34791 ENSG00000177599 "Zinc finger protein 491" Q8N8L2 19 11797667-11809622 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 8.9" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 29.3;Cone photoreceptor cells: 22.8;Early spermatids: 85.2;Late spermatids: 53.6;Rod photoreceptor cells: 32.5" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 36.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 15: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 8 "unprognostic (2.35e-3)" "unprognostic (2.20e-1)" "unprognostic (3.83e-2)" "unprognostic (2.97e-2)" "unprognostic (9.25e-2)" "unprognostic (3.44e-2)" "unprognostic (7.44e-2)" "unprognostic (1.68e-1)" "unprognostic (1.90e-2)" "unprognostic (6.33e-2)" "unprognostic (3.31e-2)" "unprognostic (2.75e-1)" "unprognostic (1.41e-1)" "unprognostic (8.97e-2)" "unprognostic (5.05e-3)" "unprognostic (1.70e-1)" "unprognostic (4.03e-2)" "unprognostic (1.32e-2)" "unprognostic (4.24e-2)" ZNF492 "KIAA1473, ZNF115" ENSG00000229676 "Zinc finger protein 492" Q9P255 19 22634324-22667671 "Essential proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "bone marrow: 2.4;testis: 1.8" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 18.6;Early primary spermatocytes: 12.7;Erythrocyte progenitors: 26.2;Extravillous trophoblasts: 6.9;Granulosa cells: 9.7;Megakaryocyte progenitors: 8.0;Megakaryocyte-Erythroid progenitors: 6.9;Undifferentiated spermatogonia: 12.8" "Low cell type specificity" "Detected in some" "Cancer enriched" "Detected in some" 6 "Testicular Germ Cell Tumor (TCGA): 9.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Skin - Mitotic cells (Skin), Testis - Spermatocytes" NA NA "Cluster 44: Bone marrow - Nuclear processes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" "unprognostic (5.12e-2)" "unprognostic (3.93e-3)" "unprognostic (5.60e-2)" "unprognostic (1.64e-1)" "unprognostic (1.56e-2)" "unprognostic (2.00e-1)" "unprognostic (4.75e-3)" ZNF493 FLJ36504 ENSG00000196268 "Zinc finger protein 493" Q6ZR52 19 21397119-21427577 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 74.5;Cardiomyocytes: 92.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 27: Cerebellum - Synaptic function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 29: Neutrophils - Innate immune cellular maintenance" "potential prognostic favorable (5.46e-4)" "unprognostic (2.31e-1)" "unprognostic (1.48e-1)" "unprognostic (1.95e-2)" "unprognostic (1.47e-1)" "unprognostic (2.23e-2)" "unprognostic (1.09e-2)" "unprognostic (5.53e-2)" "unprognostic (1.44e-3)" "unprognostic (4.41e-3)" "unprognostic (1.76e-1)" "unprognostic (2.14e-2)" "unprognostic (2.82e-2)" "unprognostic (1.07e-1)" "unprognostic (4.09e-1)" "unprognostic (1.14e-3)" "unprognostic (2.95e-1)" "unprognostic (3.06e-2)" "unprognostic (3.79e-1)" "unprognostic (1.39e-2)" "unprognostic (1.37e-1)" "unprognostic (1.73e-1)" "unprognostic (3.26e-2)" "unprognostic (1.54e-2)" "unprognostic (1.02e-3)" "unprognostic (4.40e-2)" "unprognostic (1.23e-2)" "unprognostic (1.03e-2)" "unprognostic (2.38e-1)" "unprognostic (1.83e-1)" "unprognostic (7.14e-2)" ZNF496 "MGC15548, ZKSCAN17, ZSCAN49" ENSG00000162714 "Zinc finger protein 496" Q96IT1 1 247297412-247331867 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 71.3;Late spermatids: 95.7;Podocytes: 77.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025824 Approved Nucleoplasm,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 17 Nucleoplasm Cytosol "HPA025824: " "unprognostic (2.98e-2)" "unprognostic (2.70e-2)" "unprognostic (1.73e-1)" "unprognostic (1.59e-1)" "unprognostic (4.71e-1)" "unprognostic (2.51e-1)" "unprognostic (2.29e-2)" "unprognostic (1.28e-2)" "unprognostic (1.60e-1)" "unprognostic (2.72e-1)" "potential prognostic favorable (6.41e-6)" "unprognostic (3.02e-2)" "unprognostic (7.93e-2)" "unprognostic (1.10e-3)" "unprognostic (1.35e-1)" "unprognostic (3.80e-2)" "unprognostic (7.77e-3)" "unprognostic (6.74e-2)" "unprognostic (2.20e-1)" "unprognostic (1.53e-1)" "unprognostic (1.71e-1)" "unprognostic (3.52e-1)" "unprognostic (4.87e-2)" "unprognostic (1.83e-1)" "unprognostic (5.12e-2)" "unprognostic (1.11e-1)" "unprognostic (3.02e-2)" "unprognostic (9.90e-2)" "unprognostic (3.85e-2)" "unprognostic (9.82e-3)" "unprognostic (1.19e-2)" ZNF497 FLJ44773 ENSG00000174586 "Zinc finger protein 497" Q6ZNH5 19 58354357-58362848 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 3.7;Bergmann glia: 4.4;Brain excitatory neurons: 5.5;Brain inhibitory neurons: 5.3;Cardiomyocytes: 3.9;Choroid plexus epithelial cells: 7.6;Distal convoluted tubule cells: 4.1;Ependymal cells: 18.1;Loop of henle epithelial cells: 6.6;Oligodendrocytes: 5.0;Other brain neurons: 3.3;Podocytes: 7.5;Proximal tubule cells: 7.1;Renal collecting duct intercalated cells: 5.1;Renal collecting duct principal cells: 6.3;Renal connecting tubule cells: 5.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Sertoli cells" HPA047872 Uncertain Approved "Nucleoplasm,Cell Junctions" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 64: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 34: Ciliated cells - Cilia assembly & function" 42 Nucleoplasm "Cell Junctions" "HPA047872: " "unprognostic (5.29e-2)" "unprognostic (6.62e-2)" "unprognostic (1.09e-1)" "unprognostic (7.55e-2)" "unprognostic (1.16e-1)" "unprognostic (3.79e-1)" "unprognostic (1.69e-1)" "unprognostic (1.61e-1)" "unprognostic (1.21e-1)" "unprognostic (2.30e-1)" "unprognostic (2.08e-1)" "unprognostic (6.28e-2)" "unprognostic (3.21e-2)" "unprognostic (1.41e-1)" "unprognostic (6.23e-2)" "unprognostic (1.80e-1)" "unprognostic (6.88e-2)" "unprognostic (1.59e-1)" "unprognostic (1.05e-2)" "unprognostic (1.46e-1)" "unprognostic (1.79e-1)" "unprognostic (3.41e-3)" "unprognostic (1.30e-2)" "potential prognostic unfavorable (4.52e-4)" "unprognostic (9.07e-2)" "unprognostic (2.73e-1)" "unprognostic (4.65e-2)" "unprognostic (1.58e-1)" "unprognostic (1.72e-2)" "unprognostic (6.97e-3)" "unprognostic (4.82e-3)" ZNF500 "KIAA0557, ZKSCAN18, ZSCAN50" ENSG00000103199 "Zinc finger protein 500" O60304 16 4748239-4767624 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 14.9;Distal convoluted tubule cells: 17.2;Loop of henle epithelial cells: 16.2;Myonuclei: 13.7;Podocytes: 18.1;Proximal tubule cells: 18.4;Renal collecting duct intercalated cells: 15.3;Renal collecting duct principal cells: 14.4;Renal connecting tubule cells: 15.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035498, HPA057963" Supported Enhanced Nucleoplasm,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 64: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 105: Non-specific - Mixed function" 8 Nucleoplasm Cytosol "HPA035498: , HPA057963: " "unprognostic (3.30e-2)" "unprognostic (2.73e-1)" "unprognostic (2.03e-1)" "unprognostic (2.93e-2)" "unprognostic (1.24e-1)" "unprognostic (2.07e-2)" "unprognostic (9.31e-2)" "unprognostic (3.39e-3)" "unprognostic (1.45e-2)" "unprognostic (9.35e-3)" "unprognostic (4.07e-2)" "unprognostic (2.10e-3)" "unprognostic (4.42e-2)" "unprognostic (3.08e-2)" "unprognostic (1.86e-1)" "unprognostic (7.84e-2)" "unprognostic (5.78e-2)" "unprognostic (1.42e-1)" "unprognostic (3.58e-2)" "unprognostic (1.26e-2)" "unprognostic (2.51e-1)" "unprognostic (1.13e-2)" "unprognostic (1.69e-1)" "unprognostic (3.32e-2)" "potential prognostic favorable (3.40e-5)" "unprognostic (4.23e-2)" "unprognostic (1.54e-3)" "unprognostic (1.56e-2)" "unprognostic (3.14e-1)" "unprognostic (3.54e-2)" "unprognostic (4.61e-2)" ZNF501 "MGC21738, ZNF52" ENSG00000186446 "Zinc finger protein 501" Q96CX3 3 44729596-44737083 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 4.8;Bergmann glia: 8.5;Brain excitatory neurons: 3.2;Brain inhibitory neurons: 3.6;Ependymal cells: 2.9;Microglia: 4.0;Oligodendrocyte progenitor cells: 7.3;Oligodendrocytes: 5.3;Podocytes: 2.6;Renal collecting duct principal cells: 3.2;Respiratory ionocytes: 2.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in some" "Testis - Spermatogonia" HPA044161 Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 65: Brain - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 98: Neurons - Neurotransmission & signaling" "Endoplasmic reticulum" "HPA044161: " "unprognostic (6.81e-2)" "unprognostic (4.10e-2)" "unprognostic (5.31e-2)" "unprognostic (4.58e-2)" "unprognostic (3.32e-1)" "unprognostic (3.21e-2)" "unprognostic (8.01e-2)" "unprognostic (1.85e-1)" "unprognostic (1.14e-1)" "unprognostic (3.56e-1)" "unprognostic (3.29e-1)" "unprognostic (2.48e-1)" "unprognostic (1.52e-1)" ZNF502 "FLJ12515, FLJ14855" ENSG00000196653 "Zinc finger protein 502" Q8TBZ5 3 44712643-44723831 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 5.0;Bergmann glia: 7.9;Brain excitatory neurons: 6.9;Brain inhibitory neurons: 7.5;Distal convoluted tubule cells: 5.9;Ependymal cells: 3.7;Loop of henle epithelial cells: 6.2;Microglia: 5.7;Oligodendrocyte progenitor cells: 6.8;Oligodendrocytes: 4.2;Other brain neurons: 6.2;Papillary tip epithelial cells: 6.6;Podocytes: 6.5;Proximal tubule cells: 5.8;Renal collecting duct intercalated cells: 5.9;Renal collecting duct principal cells: 5.4;Renal connecting tubule cells: 7.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA024761, HPA029557" Uncertain NA NA "Cluster 24: Non-specific - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 98: Neurons - Neurotransmission & signaling" 1 "HPA024761: , HPA029557: " "unprognostic (1.79e-3)" "unprognostic (3.07e-1)" "unprognostic (2.02e-1)" "unprognostic (1.74e-1)" "unprognostic (4.33e-2)" "unprognostic (3.53e-2)" "unprognostic (1.60e-1)" "unprognostic (3.10e-2)" "unprognostic (3.28e-3)" "potential prognostic favorable (7.11e-4)" "unprognostic (4.18e-2)" "potential prognostic favorable (5.65e-4)" "unprognostic (7.63e-2)" "unprognostic (2.83e-2)" "unprognostic (2.83e-2)" "unprognostic (3.07e-1)" "unprognostic (2.24e-2)" "unprognostic (4.68e-3)" "unprognostic (3.12e-1)" "unprognostic (3.24e-2)" "unprognostic (2.44e-3)" "unprognostic (5.86e-2)" "unprognostic (1.72e-1)" "unprognostic (1.83e-1)" ZNF503 "FLJ45745, MGC2555, Nlz2" ENSG00000165655 "Zinc finger protein 503" Q96F45 10 75397830-75401764 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.3;Endometrial secretory cells: 1.6;Endometrial stromal cells: 1.2;Fallopian secretory cells: 1.0;Fallopian tube ciliated cells: 1.7;Fibroblasts: 1.1;Gastric chief cells: 2.2;Salivary ionocytes: 1.1;Schwann cells: 1.5;Vascular smooth muscle cells: 1.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Ovary Serous Cystadenocarcinoma (TCGA): 90.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Smooth muscle cells, Spleen - Fibroblasts_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA026848 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 43: Hindbrain - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 108: Fibroblasts - ECM organization" 12 "Plasma membrane, Cytosol" Nucleoplasm "HPA026848: " "unprognostic (6.07e-2)" "unprognostic (3.13e-2)" "unprognostic (7.32e-2)" "unprognostic (4.04e-2)" "unprognostic (4.21e-1)" "unprognostic (1.47e-1)" "unprognostic (3.95e-1)" "unprognostic (1.40e-1)" "unprognostic (7.37e-2)" "unprognostic (1.93e-1)" "unprognostic (2.43e-3)" "unprognostic (2.87e-2)" "unprognostic (1.62e-1)" "unprognostic (9.86e-2)" "unprognostic (1.43e-1)" "unprognostic (2.42e-3)" "unprognostic (1.58e-1)" "unprognostic (3.89e-2)" "unprognostic (3.62e-1)" "unprognostic (4.35e-2)" "unprognostic (2.21e-1)" "unprognostic (1.20e-1)" "unprognostic (2.16e-2)" "potential prognostic unfavorable (1.82e-4)" "unprognostic (1.45e-1)" "unprognostic (1.19e-2)" "unprognostic (2.03e-1)" "unprognostic (1.86e-1)" "unprognostic (9.41e-2)" "unprognostic (1.11e-2)" "unprognostic (1.93e-1)" ZNF506 DKFZp761G1812 ENSG00000081665 "Zinc finger protein 506" Q5JVG8 19 19785839-19821751 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Tuft cells: 23.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" "potential prognostic favorable (6.95e-4)" "unprognostic (6.86e-3)" "unprognostic (2.64e-1)" "unprognostic (4.96e-2)" "unprognostic (3.00e-1)" "unprognostic (2.20e-1)" "unprognostic (5.29e-3)" "unprognostic (5.86e-2)" "unprognostic (1.61e-3)" "unprognostic (5.89e-2)" "unprognostic (1.39e-3)" "unprognostic (2.64e-3)" "unprognostic (1.76e-2)" "unprognostic (1.15e-1)" "unprognostic (7.48e-2)" "potential prognostic favorable (9.43e-4)" "unprognostic (2.49e-1)" "unprognostic (3.26e-2)" "unprognostic (1.01e-1)" "unprognostic (6.76e-2)" "unprognostic (9.91e-3)" "unprognostic (1.33e-2)" "unprognostic (3.08e-2)" "potential prognostic unfavorable (5.38e-4)" "unprognostic (2.84e-2)" "unprognostic (2.28e-1)" "unprognostic (6.14e-3)" "unprognostic (1.39e-1)" "unprognostic (2.15e-1)" "unprognostic (4.73e-2)" "unprognostic (3.74e-2)" ZNF507 "KIAA1084, Zfp507" ENSG00000168813 "Zinc finger protein 507" Q8TCN5 19 32345594-32387667 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030964, HPA049728" Uncertain Approved Nucleoli,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 2 Nucleoli Cytosol "HPA030964: , HPA049728: " "unprognostic (2.12e-2)" "unprognostic (2.57e-1)" "unprognostic (2.11e-1)" "unprognostic (1.45e-1)" "unprognostic (5.61e-2)" "unprognostic (4.34e-3)" "unprognostic (4.36e-2)" "unprognostic (1.86e-1)" "unprognostic (1.96e-2)" "unprognostic (4.69e-2)" "validated prognostic favorable (1.81e-4)" "validated prognostic favorable (2.43e-4)" "unprognostic (1.33e-1)" "unprognostic (4.29e-3)" "unprognostic (1.62e-1)" "unprognostic (2.63e-2)" "unprognostic (2.50e-2)" "unprognostic (9.20e-3)" "potential prognostic favorable (9.48e-4)" "unprognostic (2.18e-2)" "unprognostic (8.67e-3)" "unprognostic (2.01e-1)" "unprognostic (3.89e-3)" "unprognostic (1.37e-1)" "unprognostic (7.96e-3)" "unprognostic (2.51e-1)" "unprognostic (3.94e-2)" "unprognostic (1.15e-1)" "unprognostic (3.07e-1)" "unprognostic (2.08e-2)" "unprognostic (5.62e-2)" ZNF510 KIAA0972 ENSG00000081386 "Zinc finger protein 510" Q9Y2H8 9 96754553-96778129 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA049139 Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 31: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" Nucleoplasm "Vesicles, Plasma membrane" "HPA049139: " "unprognostic (4.38e-3)" "unprognostic (2.24e-2)" "unprognostic (3.38e-1)" "unprognostic (2.60e-2)" "unprognostic (1.37e-1)" "unprognostic (4.73e-3)" "unprognostic (8.76e-2)" "unprognostic (1.33e-3)" "unprognostic (4.25e-3)" "unprognostic (1.78e-2)" "validated prognostic favorable (1.93e-6)" "validated prognostic favorable (1.57e-4)" "unprognostic (3.26e-2)" "unprognostic (3.10e-1)" "unprognostic (9.35e-2)" "unprognostic (4.14e-2)" "unprognostic (4.73e-2)" "unprognostic (3.70e-1)" "unprognostic (2.18e-2)" "unprognostic (1.39e-2)" "unprognostic (8.92e-2)" "unprognostic (9.17e-2)" "unprognostic (2.03e-1)" "unprognostic (9.52e-2)" "unprognostic (9.63e-3)" "unprognostic (9.68e-2)" "unprognostic (1.37e-2)" "unprognostic (1.25e-1)" "unprognostic (1.13e-1)" "unprognostic (1.28e-1)" "unprognostic (3.69e-1)" ZNF511 "MGC30006, Zfp511" ENSG00000198546 "Zinc finger protein 511" Q8NB15 10 133308914-133313162 "Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epicardial cells: 31.8;Gastric chief cells: 20.7;Late primary spermatocytes: 27.3;Oocytes: 23.0;Paneth cells: 23.2" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035360 Uncertain Approved "Nucleoplasm,Nuclear bodies,Vesicles" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 97: Non-specific - Cellular respiration" 14 "Nuclear bodies" "Nucleoplasm, Vesicles" "HPA035360: " "unprognostic (2.17e-3)" "unprognostic (1.22e-1)" "unprognostic (1.14e-2)" "unprognostic (1.83e-1)" "unprognostic (4.27e-2)" "unprognostic (1.33e-1)" "unprognostic (1.49e-1)" "unprognostic (1.26e-2)" "unprognostic (1.68e-1)" "unprognostic (9.28e-2)" "unprognostic (6.72e-3)" "unprognostic (1.35e-1)" "unprognostic (3.76e-2)" "unprognostic (9.73e-3)" "unprognostic (8.55e-3)" "unprognostic (1.97e-1)" "unprognostic (1.55e-2)" "unprognostic (2.38e-1)" "unprognostic (1.78e-1)" "unprognostic (3.10e-1)" "unprognostic (1.17e-1)" "unprognostic (1.38e-1)" "unprognostic (1.19e-1)" "unprognostic (9.04e-3)" "unprognostic (1.12e-1)" "unprognostic (1.02e-1)" "unprognostic (7.63e-2)" "unprognostic (2.32e-2)" "unprognostic (3.16e-1)" "unprognostic (3.11e-1)" "unprognostic (1.54e-2)" ZNF511-PRAP1 ENSG00000283496 "ZNF511-PRAP1 readthrough" 10 133309410-133352529 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 4.5;lymphoid tissue: 1.1" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 14.1;Brain inhibitory neurons: 16.1;Corticotrophs: 11.7;Early primary spermatocytes: 68.3;Ependymal cells: 11.6;Gonadotrophs: 19.9;Lactotrophs: 26.0;Other brain neurons: 21.1;Retinal amacrine cells: 22.8;Retinal bipolar cells: 30.8;Retinal ganglion cells: 30.9;Retinal horizontal cells: 28.0" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 10.2;Rectum Adenocarcinoma (TCGA): 11.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035360, HPA038713, HPA052451" Supported Uncertain "Nucleoplasm,Nuclear bodies,Vesicles" NA NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 3: Early primary spermatocytes - Early meiosis" "Nuclear bodies" "Nucleoplasm, Vesicles" "HPA035360: , HPA038713: , HPA052451: " "unprognostic (1.42e-1)" "unprognostic (1.48e-1)" "potential prognostic favorable (4.71e-4)" "unprognostic (5.65e-3)" "unprognostic (1.15e-1)" "unprognostic (2.10e-3)" "unprognostic (3.25e-1)" "unprognostic (3.84e-1)" "unprognostic (3.31e-1)" "unprognostic (1.57e-1)" "unprognostic (1.10e-1)" ZNF512 KIAA1805 ENSG00000243943 "Zinc finger protein 512" Q96ME7 2 27582969-27623217 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Distal convoluted tubule cells: 37.1;Loop of henle epithelial cells: 42.9;Papillary tip epithelial cells: 44.5;Podocytes: 51.1;Proximal tubule cells: 33.2;Renal collecting duct intercalated cells: 48.9;Renal collecting duct principal cells: 43.7;Renal connecting tubule cells: 43.4" "Cell type enhanced" "Detected in single" "leukocyte: 1.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031430 Approved Approved Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 105: Non-specific - Mixed function" 71 Nucleoplasm "HPA031430: " "unprognostic (2.92e-2)" "unprognostic (1.36e-1)" "unprognostic (9.60e-2)" "unprognostic (3.32e-1)" "unprognostic (2.95e-2)" "unprognostic (9.66e-2)" "unprognostic (1.01e-1)" "unprognostic (8.94e-3)" "unprognostic (2.31e-2)" "unprognostic (2.55e-1)" "potential prognostic favorable (5.94e-5)" "unprognostic (6.84e-3)" "unprognostic (3.41e-1)" "unprognostic (4.49e-2)" "unprognostic (1.27e-2)" "unprognostic (3.36e-3)" "unprognostic (2.18e-2)" "unprognostic (2.26e-2)" "unprognostic (5.16e-2)" "unprognostic (1.04e-1)" "unprognostic (2.97e-1)" "unprognostic (8.72e-2)" "unprognostic (2.83e-2)" "unprognostic (1.43e-1)" "unprognostic (2.17e-1)" "unprognostic (7.73e-3)" "unprognostic (8.88e-2)" "unprognostic (2.31e-1)" "unprognostic (3.39e-1)" "unprognostic (2.92e-2)" "unprognostic (3.87e-1)" ZNF512B "GM632, MGC149845, MGC149846" ENSG00000196700 "Zinc finger protein 512B" Q96KM6 20 63956704-63969930 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006688, HPA008731" Approved Enhanced Nucleoplasm NA NA "Cluster 64: Non-specific - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 36 Nucleoplasm "HPA006688: , HPA008731: " "unprognostic (4.36e-2)" "unprognostic (6.55e-2)" "unprognostic (6.69e-2)" "unprognostic (1.77e-3)" "unprognostic (2.61e-2)" "unprognostic (4.15e-1)" "unprognostic (1.76e-1)" "unprognostic (3.61e-3)" "unprognostic (3.17e-1)" "unprognostic (5.03e-2)" "unprognostic (2.65e-1)" "unprognostic (2.20e-1)" "unprognostic (8.65e-3)" "potential prognostic unfavorable (6.63e-4)" "unprognostic (1.74e-1)" "unprognostic (3.34e-3)" "unprognostic (6.57e-2)" "unprognostic (1.59e-1)" "unprognostic (3.39e-2)" "unprognostic (7.97e-2)" "unprognostic (5.81e-2)" "unprognostic (3.85e-3)" "unprognostic (1.01e-2)" "potential prognostic unfavorable (7.63e-4)" "unprognostic (2.61e-1)" "unprognostic (1.50e-2)" "unprognostic (1.78e-1)" "unprognostic (2.10e-2)" "unprognostic (3.02e-1)" "potential prognostic unfavorable (4.34e-4)" "unprognostic (2.55e-1)" ZNF513 "FLJ32203, RP58, Zfp513" ENSG00000163795 "Zinc finger protein 513" Q8N8E2 2 27377235-27380790 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Sensory transduction, Transcription, Transcription regulation, Vision" DNA-binding "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 48.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051493 Uncertain NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 70: Non-specific - Protein processing" "Cluster 38: Sub-cortical - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 3 "HPA051493: " "unprognostic (2.42e-2)" "unprognostic (3.63e-1)" "unprognostic (4.57e-3)" "unprognostic (3.39e-3)" "unprognostic (9.85e-2)" "unprognostic (2.50e-2)" "unprognostic (1.04e-1)" "unprognostic (5.85e-2)" "unprognostic (4.61e-2)" "unprognostic (2.02e-1)" "potential prognostic unfavorable (1.30e-4)" "unprognostic (6.83e-2)" "unprognostic (4.07e-3)" "potential prognostic unfavorable (2.44e-5)" "unprognostic (1.54e-1)" "unprognostic (1.41e-2)" "unprognostic (1.09e-1)" "unprognostic (7.05e-2)" "unprognostic (6.52e-2)" "unprognostic (9.98e-2)" "unprognostic (1.11e-3)" "unprognostic (4.18e-2)" "unprognostic (6.99e-2)" "unprognostic (1.30e-1)" "unprognostic (2.82e-1)" "unprognostic (1.38e-1)" "unprognostic (4.99e-2)" "unprognostic (2.18e-1)" "unprognostic (1.75e-1)" "unprognostic (8.14e-2)" "unprognostic (1.43e-1)" ZNF514 FLJ14457 ENSG00000144026 "Zinc finger protein 514" Q96K75 2 95122087-95165668 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 22.0;Late primary spermatocytes: 22.9;Late spermatids: 28.6;Microglia: 13.0;Oligodendrocytes: 14.4;Other brain neurons: 10.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028974 Approved Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 64: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 4: Non-specific - Transcription" "Cluster 98: Neurons - Neurotransmission & signaling" 1 "Nuclear bodies" Nucleoplasm "HPA028974: " "unprognostic (1.38e-1)" "unprognostic (2.44e-2)" "unprognostic (7.66e-2)" "unprognostic (1.53e-1)" "potential prognostic unfavorable (1.22e-5)" "unprognostic (6.46e-2)" "unprognostic (1.26e-1)" "unprognostic (2.95e-2)" "unprognostic (3.50e-1)" "unprognostic (1.89e-2)" "unprognostic (3.73e-2)" "unprognostic (1.74e-2)" "unprognostic (2.18e-3)" "unprognostic (2.18e-3)" "unprognostic (1.99e-2)" "unprognostic (8.67e-3)" "unprognostic (1.62e-1)" "unprognostic (8.74e-2)" "unprognostic (7.17e-3)" "unprognostic (3.61e-2)" "unprognostic (1.82e-1)" "unprognostic (1.61e-3)" "unprognostic (1.59e-3)" "unprognostic (3.55e-1)" "unprognostic (2.01e-3)" "unprognostic (1.84e-1)" "unprognostic (3.96e-2)" "unprognostic (3.40e-1)" "unprognostic (1.02e-1)" "unprognostic (1.35e-1)" "unprognostic (1.83e-1)" ZNF516 "HsT287, KIAA0222" ENSG00000101493 "Zinc finger protein 516" Q92618 18 76357682-76495242 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 323.9;Endometrial stromal cells: 398.0;Neutrophil progenitors: 334.0;Neutrophils: 677.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 10.3" "Lineage enriched" "Detected in many" 6 "granulocytes: 10.3" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015792 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 75: Ovary - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 24 Nucleoplasm Cytosol "HPA015792: " "unprognostic (1.31e-3)" "unprognostic (2.19e-1)" "unprognostic (1.71e-1)" "unprognostic (2.73e-1)" "unprognostic (1.33e-1)" "unprognostic (1.61e-1)" "unprognostic (4.10e-1)" "unprognostic (5.54e-3)" "unprognostic (2.80e-1)" "unprognostic (2.66e-1)" "validated prognostic favorable (3.64e-6)" "validated prognostic favorable (9.15e-4)" "unprognostic (1.48e-1)" "potential prognostic unfavorable (4.07e-4)" "unprognostic (8.23e-2)" "unprognostic (1.07e-2)" "unprognostic (2.26e-1)" "unprognostic (1.43e-1)" "unprognostic (6.38e-2)" "unprognostic (8.61e-2)" "unprognostic (2.35e-1)" "unprognostic (6.57e-2)" "unprognostic (1.45e-1)" "unprognostic (2.32e-1)" "unprognostic (6.06e-2)" "unprognostic (5.34e-3)" "unprognostic (1.91e-1)" "unprognostic (7.44e-2)" "unprognostic (1.32e-1)" "unprognostic (2.51e-2)" "unprognostic (7.62e-2)" ZNF517 ENSG00000197363 "Zinc finger protein 517" Q6ZMY9 8 144798876-144811169 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 12.9;Megakaryocytes: 12.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055337 Supported Nucleoplasm NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 64: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" Nucleoplasm "HPA055337: " "unprognostic (9.78e-3)" "unprognostic (1.48e-2)" "unprognostic (7.81e-2)" "unprognostic (2.27e-3)" "unprognostic (1.74e-2)" "unprognostic (3.17e-2)" "unprognostic (1.13e-1)" "unprognostic (4.46e-3)" "unprognostic (8.38e-2)" "unprognostic (2.47e-1)" "unprognostic (6.77e-2)" "unprognostic (5.36e-2)" "unprognostic (7.42e-3)" "unprognostic (1.88e-2)" "unprognostic (5.25e-2)" "unprognostic (2.21e-1)" "unprognostic (4.54e-2)" "unprognostic (1.41e-1)" "unprognostic (1.83e-2)" "unprognostic (3.91e-1)" "unprognostic (2.83e-2)" "unprognostic (1.42e-3)" "potential prognostic unfavorable (2.58e-4)" "unprognostic (1.59e-1)" "unprognostic (3.72e-2)" "unprognostic (2.80e-1)" "unprognostic (8.08e-2)" "unprognostic (6.95e-2)" "unprognostic (5.11e-1)" "potential prognostic unfavorable (4.83e-4)" "unprognostic (1.71e-1)" ZNF518A "KIAA0335, ZNF518" ENSG00000177853 "Zinc finger protein 518A" Q6AHZ1 10 96129715-96205288 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Sertoli cells: 684.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029049 Approved Nucleoplasm Yes No "Cluster 35: Neutrophils - Protein binding" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 3 Nucleoplasm "HPA029049: " "unprognostic (1.24e-1)" "unprognostic (4.18e-2)" "unprognostic (5.05e-2)" "unprognostic (3.03e-2)" "unprognostic (1.57e-1)" "unprognostic (4.95e-1)" "unprognostic (6.54e-2)" "unprognostic (1.54e-3)" "unprognostic (7.36e-3)" "unprognostic (3.35e-1)" "unprognostic (3.40e-3)" "unprognostic (8.01e-3)" "unprognostic (2.23e-2)" "unprognostic (6.39e-2)" "unprognostic (1.67e-2)" "unprognostic (5.54e-2)" "unprognostic (1.10e-1)" "unprognostic (2.52e-1)" "unprognostic (4.44e-2)" "unprognostic (1.95e-1)" "unprognostic (1.52e-1)" "unprognostic (1.10e-1)" "unprognostic (2.84e-2)" "unprognostic (2.84e-2)" "unprognostic (1.20e-3)" "unprognostic (1.84e-1)" "unprognostic (9.55e-2)" "unprognostic (1.72e-1)" "unprognostic (3.88e-1)" "potential prognostic unfavorable (1.68e-4)" "unprognostic (3.11e-1)" ZNF518B KIAA1729 ENSG00000178163 "Zinc finger protein 518B" Q9C0D4 4 10439880-10457426 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 84.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031215, HPA031216" Approved Approved Nucleoplasm NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 4: Non-specific - Transcription" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 1 Nucleoplasm "HPA031215: , HPA031216: " "unprognostic (2.14e-1)" "unprognostic (9.51e-2)" "unprognostic (8.67e-3)" "unprognostic (2.12e-1)" "unprognostic (2.96e-1)" "unprognostic (1.45e-2)" "unprognostic (1.81e-1)" "unprognostic (2.75e-1)" "unprognostic (2.72e-2)" "unprognostic (8.66e-2)" "potential prognostic favorable (1.14e-5)" "unprognostic (7.77e-2)" "potential prognostic unfavorable (7.51e-4)" "unprognostic (6.96e-2)" "unprognostic (2.51e-1)" "unprognostic (1.36e-1)" "unprognostic (1.51e-1)" "unprognostic (5.98e-3)" "unprognostic (7.34e-2)" "unprognostic (7.89e-2)" "unprognostic (2.32e-1)" "unprognostic (2.52e-1)" "unprognostic (8.61e-2)" "unprognostic (1.55e-2)" "unprognostic (6.50e-2)" "unprognostic (1.81e-1)" "unprognostic (1.62e-1)" "unprognostic (1.05e-1)" "unprognostic (2.08e-1)" "unprognostic (1.81e-1)" ZNF519 "FLJ36809, HsT2362" ENSG00000175322 "Zinc finger protein 519" Q8TB69 18 14057457-14132490 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.8" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 69.3;Brain inhibitory neurons: 62.2;Esophageal apical cells: 63.3;Fibro-adipogenic progenitors: 75.2;Myonuclei: 57.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatic stellate cells, Stomach - Fibroblasts, Testis - Peritubular cells" HPA028982 Uncertain Approved Nucleoli NA NA "Cluster 64: Non-specific - Transcription" "Cluster 35: Non-specific - DNA binding" "Cluster 4: Non-specific - Transcription" "Cluster 35: Neurons - Synaptic function & neurogenesis" Nucleoli "HPA028982: " "unprognostic (1.78e-2)" "unprognostic (4.87e-3)" "unprognostic (3.42e-1)" "potential prognostic unfavorable (2.84e-4)" "unprognostic (1.67e-1)" ZNF521 "EHZF, Evi3" ENSG00000198795 "Zinc finger protein 521" Q96K83 18 25061924-25352190 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 59.3" "Cell type enhanced" "Detected in many" "Adipocytes: 312.3;Adrenal cortex cells: 303.6;Astrocytes: 314.5;Brain excitatory neurons: 290.8;Choroid plexus epithelial cells: 1004.7;Fibro-adipogenic progenitors: 399.8;Hematopoietic stem cells: 282.9;Lactotrophs: 273.4;Lymphatic endothelial cells: 562.9;Oligodendrocyte progenitor cells: 293.5;Pituicytes/FSCs: 518.3;Pituitary stem cells: 1119.9" "Cell type enhanced" "Detected in all" "cerebellar inhibitory: 963.0;choroid plexus epithelial cell: 765.2;upper rhombic lip: 967.5" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 23.9" "Region enhanced" "Detected in all" "cerebellum: 203.9" "Group enriched" "Detected in some" 6 "basophil: 11.4;plasmacytoid DC: 8.8" "Group enriched" "Detected in many" 6 "dendritic cells: 8.8;granulocytes: 11.4" "Cancer enhanced" "Detected in many" "Leukemia: 17.1;Rhabdoid: 27.7" "Lung - Fibroblasts_2, Pituitary gland - Undifferentiated cells (Pituitary gland), Prostate - Endothelial cells, Spleen - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebellum: 66.7" "HPA023056, HPA023849" Enhanced Enhanced Nucleoplasm NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 71: Cerebellum - Nervous system development" "Cluster 25: Non-specific - Transcription" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 7 Nucleoplasm "HPA023056: , HPA023849: " "unprognostic (7.77e-3)" "unprognostic (6.42e-3)" "unprognostic (1.64e-1)" "unprognostic (1.08e-1)" "unprognostic (4.35e-2)" "unprognostic (4.22e-1)" "unprognostic (1.07e-1)" "unprognostic (6.58e-2)" "unprognostic (8.98e-3)" "unprognostic (5.20e-2)" "potential prognostic favorable (1.84e-6)" "unprognostic (4.43e-2)" "unprognostic (1.31e-1)" "unprognostic (1.11e-1)" "unprognostic (2.72e-2)" "unprognostic (9.04e-2)" "unprognostic (5.15e-2)" "unprognostic (1.18e-2)" "unprognostic (1.30e-1)" "unprognostic (1.41e-1)" "unprognostic (1.28e-1)" "unprognostic (1.82e-1)" "unprognostic (3.50e-3)" "unprognostic (6.33e-2)" "potential prognostic unfavorable (6.91e-4)" "unprognostic (1.95e-1)" "unprognostic (2.88e-3)" "unprognostic (3.14e-2)" ZNF524 MGC23143 ENSG00000171443 "Zinc finger protein 524" Q96C55 19 55600022-55603138 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 86.2;Esophageal apical cells: 141.4;Paneth cells: 85.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050981 Uncertain Approved Nucleoplasm NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 24: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 4: Non-specific - Transcription" "Cluster 15: Non-specific - Protein processing" 45 Nucleoplasm "HPA050981: " "potential prognostic favorable (3.14e-5)" "unprognostic (1.92e-2)" "unprognostic (3.49e-1)" "unprognostic (6.15e-2)" "unprognostic (1.82e-1)" "unprognostic (3.67e-2)" "unprognostic (2.19e-1)" "unprognostic (3.43e-1)" "unprognostic (4.39e-2)" "unprognostic (4.39e-1)" "unprognostic (5.44e-3)" "unprognostic (3.00e-2)" "potential prognostic favorable (5.98e-4)" "potential prognostic unfavorable (4.50e-5)" "unprognostic (7.67e-2)" "unprognostic (3.61e-2)" "unprognostic (3.94e-1)" "unprognostic (3.39e-2)" "unprognostic (1.50e-1)" "unprognostic (9.50e-2)" "unprognostic (7.51e-2)" "unprognostic (9.88e-2)" "unprognostic (3.76e-2)" "unprognostic (9.17e-2)" "unprognostic (6.51e-2)" "unprognostic (7.50e-2)" "unprognostic (9.51e-2)" "unprognostic (3.27e-2)" "unprognostic (2.37e-1)" "unprognostic (1.60e-1)" "unprognostic (5.47e-2)" ZNF525 KIAA1979 ENSG00000203326 "Zinc finger protein 525" Q8N782 19 53365693-53392217 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" "potential prognostic favorable (2.01e-4)" "unprognostic (3.02e-3)" "unprognostic (2.55e-1)" "unprognostic (6.10e-2)" "unprognostic (6.06e-2)" "unprognostic (2.32e-2)" "unprognostic (2.32e-1)" "unprognostic (3.87e-2)" "unprognostic (1.64e-1)" "unprognostic (8.71e-3)" "unprognostic (3.25e-2)" "unprognostic (2.60e-2)" "unprognostic (1.72e-2)" "unprognostic (6.74e-3)" "unprognostic (8.79e-2)" "unprognostic (6.01e-3)" "unprognostic (3.19e-3)" "unprognostic (5.78e-2)" "unprognostic (5.09e-2)" "unprognostic (2.26e-1)" "unprognostic (1.33e-1)" "unprognostic (1.76e-1)" "unprognostic (2.28e-3)" "unprognostic (3.45e-3)" "unprognostic (2.40e-1)" "unprognostic (5.45e-2)" "potential prognostic unfavorable (7.59e-6)" "unprognostic (9.63e-2)" "unprognostic (2.87e-2)" "unprognostic (1.05e-1)" "unprognostic (5.59e-2)" ZNF526 "KIAA1951, MGC4267" ENSG00000167625 "Zinc finger protein 526" Q8TF50 19 42220312-42228201 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023070, HPA056609" Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 49: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 4: Non-specific - Transcription" "Cluster 65: Non-specific - Cell growth & division" 48 "Nucleoplasm, Golgi apparatus, Vesicles" "HPA023070: , HPA056609: " "unprognostic (3.12e-2)" "unprognostic (2.38e-1)" "unprognostic (2.71e-1)" "unprognostic (3.23e-3)" "unprognostic (3.24e-1)" "unprognostic (1.37e-1)" "unprognostic (3.85e-1)" "unprognostic (1.52e-1)" "unprognostic (1.29e-1)" "unprognostic (4.37e-2)" "potential prognostic favorable (5.09e-4)" "unprognostic (6.45e-2)" "unprognostic (2.23e-1)" "unprognostic (2.58e-3)" "unprognostic (8.56e-2)" "unprognostic (4.70e-3)" "unprognostic (3.70e-2)" "unprognostic (3.28e-2)" "unprognostic (5.21e-3)" "unprognostic (4.61e-2)" "unprognostic (3.42e-2)" "unprognostic (6.85e-2)" "unprognostic (7.49e-2)" "unprognostic (4.80e-2)" "unprognostic (5.63e-2)" "unprognostic (2.52e-1)" "unprognostic (7.41e-3)" "unprognostic (1.46e-1)" "unprognostic (3.17e-2)" "unprognostic (1.59e-1)" "unprognostic (7.81e-2)" ZNF527 KIAA1829 ENSG00000189164 "Zinc finger protein 527" Q8NB42 19 37371061-37393066 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 29.2;Sertoli cells: 19.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "HPA037740, HPA037741" Uncertain Approved "Nuclear speckles,Golgi apparatus" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 61: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" "Nuclear speckles" "Golgi apparatus" "HPA037740: , HPA037741: " "unprognostic (1.01e-2)" "unprognostic (5.87e-2)" "unprognostic (3.69e-1)" "unprognostic (1.32e-1)" "unprognostic (1.00e-1)" "unprognostic (2.46e-1)" "unprognostic (9.06e-2)" "unprognostic (1.19e-1)" "unprognostic (8.18e-2)" "potential prognostic favorable (2.14e-4)" "unprognostic (1.19e-2)" "unprognostic (2.57e-2)" "unprognostic (6.31e-2)" "unprognostic (9.38e-2)" "unprognostic (8.17e-3)" "unprognostic (1.98e-1)" "unprognostic (2.37e-1)" "unprognostic (1.34e-1)" "unprognostic (3.03e-1)" "unprognostic (1.30e-1)" "unprognostic (1.32e-3)" "unprognostic (8.69e-2)" "unprognostic (3.06e-2)" "unprognostic (4.16e-1)" "unprognostic (6.94e-2)" "unprognostic (1.15e-1)" "unprognostic (4.88e-2)" "unprognostic (1.75e-1)" "unprognostic (1.65e-1)" ZNF528 KIAA1827 ENSG00000167555 "Zinc finger protein 528" Q3MIS6 19 52397849-52418412 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" HPA065435 Approved "Nuclear speckles,Cytosol" No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 22: Epididymis - Mixed function" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" "Nuclear speckles" Cytosol "HPA065435: " "unprognostic (4.85e-3)" "unprognostic (4.44e-2)" "unprognostic (9.75e-2)" "unprognostic (1.60e-3)" "unprognostic (1.36e-1)" "unprognostic (3.91e-2)" "unprognostic (8.28e-2)" "unprognostic (1.65e-1)" "unprognostic (1.25e-1)" "unprognostic (6.05e-3)" "unprognostic (1.59e-2)" "unprognostic (1.77e-3)" "unprognostic (2.57e-3)" "unprognostic (2.05e-2)" "unprognostic (5.04e-2)" "unprognostic (1.14e-1)" "unprognostic (8.48e-2)" "unprognostic (2.25e-1)" "unprognostic (1.11e-1)" "unprognostic (1.67e-2)" "unprognostic (5.64e-2)" "unprognostic (1.53e-1)" "unprognostic (1.37e-2)" "unprognostic (4.32e-1)" "unprognostic (3.17e-1)" "unprognostic (3.42e-1)" "potential prognostic unfavorable (2.29e-4)" "unprognostic (1.14e-2)" "unprognostic (1.26e-1)" "unprognostic (1.33e-1)" "unprognostic (1.20e-1)" ZNF529 KIAA1615 ENSG00000186020 "Zinc finger protein 529" Q6P280 19 36534774-36605276 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 110.4;Retinal horizontal cells: 120.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" HPA031311 Uncertain Approved Nucleoplasm NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 1 Nucleoplasm "HPA031311: " "unprognostic (2.18e-3)" "unprognostic (2.49e-1)" "unprognostic (3.47e-1)" "unprognostic (2.32e-1)" "unprognostic (2.49e-1)" "unprognostic (1.40e-1)" "potential prognostic favorable (5.27e-4)" "unprognostic (1.77e-1)" "unprognostic (4.74e-2)" "unprognostic (6.95e-2)" "unprognostic (1.90e-1)" "unprognostic (9.87e-3)" "unprognostic (1.14e-1)" "unprognostic (6.96e-2)" "unprognostic (2.57e-1)" "unprognostic (5.06e-1)" "unprognostic (2.80e-1)" "unprognostic (5.51e-2)" "unprognostic (2.02e-1)" "unprognostic (6.75e-2)" "unprognostic (1.50e-1)" "unprognostic (3.61e-3)" "unprognostic (2.98e-2)" "unprognostic (1.29e-2)" "potential prognostic favorable (7.73e-5)" "unprognostic (1.76e-1)" "unprognostic (3.44e-3)" "unprognostic (1.52e-2)" "unprognostic (1.52e-1)" "unprognostic (1.30e-1)" "unprognostic (8.57e-2)" ZNF530 KIAA1508 ENSG00000183647 "Zinc finger protein 530" Q6P9A1 19 57599885-57612722 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 5.9" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 9.4;Oocytes: 13.8;Thymic myoid cells: 19.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA045868 Uncertain Approved Vesicles NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 48: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 46: Skeletal myocytes - Muscle structure & formation" Vesicles "HPA045868: " "unprognostic (5.10e-2)" "unprognostic (2.52e-1)" "unprognostic (1.43e-2)" "unprognostic (2.82e-2)" "unprognostic (2.14e-1)" "unprognostic (3.04e-1)" "unprognostic (2.61e-1)" "unprognostic (1.93e-1)" "unprognostic (6.44e-2)" "potential prognostic unfavorable (2.77e-6)" "unprognostic (2.86e-3)" "unprognostic (3.66e-2)" "unprognostic (2.89e-2)" "unprognostic (7.52e-2)" "unprognostic (7.06e-2)" "unprognostic (3.61e-3)" "unprognostic (1.22e-2)" "unprognostic (3.60e-3)" "unprognostic (3.57e-3)" "unprognostic (3.95e-2)" "unprognostic (2.15e-1)" "unprognostic (1.46e-2)" "unprognostic (3.36e-2)" "unprognostic (6.76e-2)" "unprognostic (4.43e-3)" "unprognostic (8.79e-2)" "unprognostic (2.18e-3)" "unprognostic (7.77e-2)" "unprognostic (2.77e-1)" "potential prognostic unfavorable (5.93e-5)" "unprognostic (1.05e-1)" ZNF532 FLJ10697 ENSG00000074657 "Zinc finger protein 532" Q9HCE3 18 58862600-58986480 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bergmann glia: 381.4;Myonuclei: 299.2;Pituitary stem cells: 377.3;Prostatic glandular cells: 1097.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 3.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015322 Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 13: Non-specific - Mixed function" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" Nucleoplasm "Golgi apparatus" "HPA015322: " "unprognostic (9.48e-2)" "unprognostic (3.59e-1)" "unprognostic (2.07e-1)" "unprognostic (2.30e-2)" "unprognostic (5.70e-3)" "unprognostic (2.02e-2)" "unprognostic (2.63e-1)" "unprognostic (9.39e-2)" "unprognostic (2.85e-2)" "unprognostic (6.02e-2)" "unprognostic (6.93e-3)" "unprognostic (3.09e-3)" "unprognostic (2.11e-1)" "unprognostic (1.38e-2)" "unprognostic (2.39e-1)" "unprognostic (5.73e-2)" "potential prognostic unfavorable (2.30e-4)" "unprognostic (2.74e-2)" "unprognostic (2.37e-1)" "unprognostic (1.88e-1)" "unprognostic (2.16e-1)" "unprognostic (7.53e-3)" "unprognostic (2.16e-2)" "unprognostic (2.39e-1)" "unprognostic (7.42e-2)" "unprognostic (4.20e-2)" "unprognostic (2.61e-2)" "unprognostic (8.38e-2)" "unprognostic (5.58e-1)" "unprognostic (4.26e-2)" "unprognostic (7.97e-2)" ZNF534 "FLJ25344, KRBO3" ENSG00000198633 "Zinc finger protein 534" Q76KX8 19 52429148-52452315 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 2.4;retina: 1.0;testis: 1.8" "Cell type enhanced" "Detected in some" "Bergmann glia: 5.6;Brain excitatory neurons: 7.9;Brain inhibitory neurons: 10.7;Differentiating spermatogonia: 22.0;Early primary spermatocytes: 12.5;Oocytes: 18.4;Retinal amacrine cells: 12.3;Retinal horizontal cells: 8.0;Undifferentiated spermatogonia: 12.2" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in single" 17 "Testicular Germ Cell Tumor (TCGA): 7.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 20 "Adrenocortical cancer: 16.2" HPA078521 Approved Mitochondria NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 34: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 35: Neurons - Synaptic function & neurogenesis" 3 Mitochondria "HPA078521: " "unprognostic (1.67e-1)" "unprognostic (1.36e-2)" "unprognostic (1.85e-1)" ZNF536 KIAA0390 ENSG00000198597 "Zinc finger protein 536" O15090 19 30224891-30713586 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.4;retina: 8.8" "Cell type enhanced" "Detected in many" "Bergmann glia: 424.0;Brain inhibitory neurons: 259.7;Choroid plexus epithelial cells: 995.1;Lactotrophs: 394.3;Müller glia: 526.9;Oligodendrocytes: 1122.5;Retinal bipolar cells: 311.0;Retinal horizontal cells: 354.6;Retinal pigment epithelial cells: 754.5;Schwann cells: 465.8;Sertoli cells: 377.2;Somatotrophs: 500.0;Thyrotrophs: 339.5" "Cell type enhanced" "Detected in all" "LAMP5-LHX6 and Chandelier: 1408.0;oligodendrocyte: 1374.0" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 2.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 9.5" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Colon - Enteric glia cells, Prostate - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077341 Approved "Nucleoplasm,Cell Junctions" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 80: Oligodendrocytes - Myelination" 7 "Nucleoplasm, Cell Junctions" "HPA077341: " "unprognostic (3.15e-2)" "unprognostic (1.77e-1)" "unprognostic (1.38e-1)" "unprognostic (1.82e-1)" "unprognostic (7.57e-2)" "unprognostic (2.20e-1)" "unprognostic (4.25e-2)" ZNF540 DKFZp547B0714 ENSG00000171817 "Zinc finger protein 540" Q8NDQ6 19 37551406-37614179 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 23.9" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 78.8;Cone photoreceptor cells: 82.8;Lactotrophs: 132.5;Retinal horizontal cells: 84.1;Rod photoreceptor cells: 114.4;Somatotrophs: 136.8;Thyrotrophs: 95.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Colon - Enteric glia cells" HPA003444 Supported Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" Nucleoplasm "Vesicles, Cytosol" "HPA003444: " "unprognostic (1.12e-1)" "unprognostic (8.11e-2)" "unprognostic (1.73e-1)" "unprognostic (7.67e-3)" "potential prognostic favorable (1.39e-4)" "unprognostic (4.50e-2)" "unprognostic (2.62e-1)" "validated prognostic favorable (8.30e-8)" "validated prognostic favorable (2.43e-5)" "unprognostic (4.56e-3)" "potential prognostic favorable (8.14e-6)" "potential prognostic favorable (4.50e-5)" "unprognostic (1.19e-1)" "potential prognostic favorable (1.29e-4)" "unprognostic (1.62e-1)" "unprognostic (1.16e-1)" "unprognostic (3.24e-1)" "unprognostic (3.95e-2)" "unprognostic (8.18e-2)" ZNF541 DKFZp434I1930 ENSG00000118156 "Zinc finger protein 541" Q9H0D2 19 47520690-47573148 "Predicted intracellular proteins, Transcription factors" "Differentiation, Meiosis, Spermatogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "testis: 21.1" "Cell type enhanced" "Detected in some" "Adrenal cortex cells: 27.7;Differentiating spermatogonia: 43.8;Early primary spermatocytes: 163.9;Early spermatids: 27.5;Epididymal efferent duct absorptive cells: 42.4;Late primary spermatocytes: 45.0;Late spermatids: 26.5;Retinal amacrine cells: 18.9;Undifferentiated spermatogonia: 39.1" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 5.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "thyroid cancer: 1.2" "Testis - Early spermatids, Testis - Spermatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA058541, HPA076453" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 67: Testis - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 3: Early primary spermatocytes - Early meiosis" 2 Nucleoplasm Cytosol "HPA058541: , HPA076453: " "unprognostic (1.51e-2)" "unprognostic (1.78e-3)" "potential prognostic favorable (1.75e-5)" "potential prognostic favorable (6.79e-6)" "unprognostic (1.33e-2)" "unprognostic (9.40e-3)" "potential prognostic favorable (8.97e-4)" ZNF543 DKFZp434H055 ENSG00000178229 "Zinc finger protein 543" Q08ER8 19 57320472-57330770 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 19.2;Late spermatids: 19.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" HPA046330 Approved Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 6 Nucleoplasm "HPA046330: " "potential prognostic favorable (2.00e-4)" "unprognostic (3.73e-1)" "unprognostic (2.57e-1)" "unprognostic (4.22e-2)" "unprognostic (1.18e-1)" "unprognostic (5.03e-2)" "unprognostic (2.72e-1)" "unprognostic (8.85e-2)" "unprognostic (1.95e-1)" "unprognostic (2.72e-1)" "validated prognostic favorable (3.54e-6)" "validated prognostic favorable (1.33e-4)" "unprognostic (2.14e-1)" "unprognostic (1.36e-1)" "unprognostic (1.01e-1)" "unprognostic (1.88e-1)" "unprognostic (1.05e-1)" "unprognostic (5.08e-2)" "unprognostic (1.24e-1)" "unprognostic (1.19e-1)" "unprognostic (5.98e-2)" "unprognostic (3.04e-1)" "unprognostic (1.53e-2)" "unprognostic (1.04e-2)" "unprognostic (5.17e-1)" "unprognostic (1.11e-2)" "unprognostic (2.76e-1)" "unprognostic (2.10e-1)" "unprognostic (1.64e-2)" "unprognostic (2.22e-1)" ZNF544 AF020591 ENSG00000198131 "Zinc finger protein 544" Q6NX49 19 58228594-58277495 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 12.4;Early primary spermatocytes: 26.1;Early spermatids: 25.8;Late primary spermatocytes: 38.1;Late spermatids: 52.1;Megakaryocytes: 18.5" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" HPA002732 Approved Approved Nucleoplasm NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 22: Epididymis - Mixed function" "Cluster 2: Neurons - Nucleosome" "Cluster 4: Non-specific - Transcription" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 5 Nucleoplasm "HPA002732: " "unprognostic (3.98e-2)" "unprognostic (2.62e-1)" "unprognostic (5.94e-2)" "unprognostic (6.76e-2)" "unprognostic (3.75e-2)" "unprognostic (8.90e-2)" "unprognostic (3.16e-2)" "unprognostic (1.33e-1)" "unprognostic (5.58e-2)" "unprognostic (1.66e-1)" "unprognostic (1.82e-2)" "unprognostic (1.53e-3)" "unprognostic (1.19e-3)" "unprognostic (1.33e-3)" "unprognostic (2.70e-1)" "unprognostic (4.30e-2)" "unprognostic (4.70e-2)" "unprognostic (5.43e-2)" "unprognostic (9.32e-2)" "unprognostic (2.74e-1)" "unprognostic (1.09e-1)" "unprognostic (1.47e-2)" "unprognostic (1.20e-1)" "unprognostic (3.30e-2)" "unprognostic (1.44e-1)" "unprognostic (1.28e-2)" "unprognostic (7.81e-2)" "unprognostic (1.05e-1)" "unprognostic (3.63e-2)" "unprognostic (1.50e-1)" "unprognostic (5.31e-2)" ZNF546 "MGC43537, ZNF49" ENSG00000187187 "Zinc finger protein 546" Q86UE3 19 39984134-40021038 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 7.3" "Cell type enhanced" "Detected in some" "Astrocytes: 20.2;Bergmann glia: 23.0;Brain excitatory neurons: 18.7;Brain inhibitory neurons: 20.6;Choroid plexus epithelial cells: 20.8;Distal convoluted tubule cells: 15.9;Ependymal cells: 21.1;Loop of henle epithelial cells: 14.9;Microglia: 29.0;Oligodendrocyte progenitor cells: 22.0;Oligodendrocytes: 27.1;Other brain neurons: 13.6;Podocytes: 18.6;Proximal tubule cells: 17.1;Renal collecting duct intercalated cells: 12.9;Renal collecting duct principal cells: 14.0;Renal connecting tubule cells: 13.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in some" "Testis - Early spermatids" "Low region specificity" "Detected in all" HPA030838 Approved Nucleoplasm,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 21: Testis - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 4: Non-specific - Transcription" "Cluster 28: Astrocytes - Homeostasis & neuron support" Nucleoplasm Cytosol "HPA030838: " "potential prognostic favorable (9.87e-4)" "unprognostic (4.62e-3)" "unprognostic (4.55e-2)" "unprognostic (1.69e-1)" "unprognostic (2.66e-1)" "unprognostic (1.94e-1)" "unprognostic (9.68e-2)" "potential prognostic favorable (4.33e-4)" "unprognostic (1.04e-1)" "unprognostic (4.71e-3)" "unprognostic (1.97e-1)" "unprognostic (4.90e-2)" "unprognostic (2.83e-2)" "unprognostic (1.62e-2)" "unprognostic (3.80e-3)" "unprognostic (1.69e-1)" "unprognostic (2.59e-2)" ZNF547 FLJ31100 ENSG00000152433 "Zinc finger protein 547" Q8IVP9 19 57363477-57379565 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in single" 5 "Platelets: 2.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" HPA056001 Uncertain NA NA "Cluster 32: Basophils - Transcription" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 35: Non-specific - DNA binding" "Cluster 4: Non-specific - Transcription" "Cluster 47: Platelets - Hemostasis" 7 "HPA056001: " "unprognostic (3.12e-2)" "unprognostic (2.11e-1)" "unprognostic (6.79e-2)" "unprognostic (4.07e-2)" "unprognostic (1.37e-1)" "unprognostic (3.01e-1)" "unprognostic (4.99e-2)" "unprognostic (1.76e-1)" "unprognostic (3.50e-1)" "unprognostic (6.87e-2)" "unprognostic (1.66e-3)" "unprognostic (3.74e-1)" "unprognostic (1.94e-1)" "unprognostic (1.68e-1)" "unprognostic (1.73e-1)" "unprognostic (1.78e-1)" "unprognostic (2.05e-1)" "unprognostic (1.59e-1)" "potential prognostic favorable (2.55e-4)" "unprognostic (2.17e-2)" "unprognostic (2.85e-3)" "unprognostic (1.08e-1)" "unprognostic (8.06e-2)" "unprognostic (2.64e-1)" "unprognostic (1.71e-1)" "unprognostic (8.99e-3)" "unprognostic (2.66e-1)" "unprognostic (1.24e-2)" ZNF548 FLJ32932 ENSG00000188785 "Zinc finger protein 548" Q8NEK5 19 57389850-57402992 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in single" "Gastric chief cells: 1.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" HPA066042 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 15: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" Nucleoplasm Cytosol "HPA066042: " "potential prognostic favorable (4.75e-4)" "unprognostic (1.60e-2)" "unprognostic (6.87e-2)" "unprognostic (1.32e-1)" "unprognostic (2.27e-1)" "unprognostic (7.03e-2)" "unprognostic (3.68e-1)" "unprognostic (3.06e-1)" "unprognostic (3.11e-2)" "unprognostic (7.58e-2)" "unprognostic (1.41e-1)" "unprognostic (1.69e-2)" "unprognostic (2.17e-1)" "unprognostic (6.58e-2)" "unprognostic (3.02e-2)" "unprognostic (5.74e-2)" "unprognostic (8.86e-2)" "unprognostic (1.16e-1)" "unprognostic (1.72e-1)" "unprognostic (1.37e-1)" "unprognostic (2.11e-1)" "unprognostic (3.30e-2)" "unprognostic (3.83e-2)" "unprognostic (5.04e-2)" "unprognostic (2.72e-2)" "unprognostic (2.70e-2)" "unprognostic (2.35e-2)" "unprognostic (1.37e-1)" "unprognostic (3.21e-1)" "unprognostic (5.12e-3)" "unprognostic (1.92e-1)" ZNF549 FLJ34917 ENSG00000121406 "Zinc finger protein 549" Q6P9A3 19 57527325-57557542 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 136.2;Myonuclei: 45.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 11.3" "Group enriched" "Detected in all" 4 "B-cells: 4.5;NK-cells: 11.3;T-cells: 4.6" "Low cancer specificity" "Detected in all" HPA039511 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 15: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 1 Nucleoplasm Cytosol "HPA039511: " "unprognostic (8.03e-2)" "unprognostic (4.30e-1)" "unprognostic (6.73e-2)" "unprognostic (4.41e-3)" "unprognostic (1.64e-1)" "unprognostic (1.21e-2)" "unprognostic (1.04e-1)" "unprognostic (3.87e-1)" "unprognostic (2.39e-1)" "unprognostic (1.20e-1)" "validated prognostic favorable (1.46e-7)" "validated prognostic favorable (1.33e-4)" "potential prognostic favorable (2.93e-4)" "unprognostic (2.68e-2)" "unprognostic (7.05e-2)" "unprognostic (6.07e-2)" "unprognostic (1.56e-1)" "unprognostic (8.25e-2)" "unprognostic (2.17e-1)" "unprognostic (3.61e-1)" "unprognostic (3.44e-3)" "unprognostic (1.18e-1)" "unprognostic (8.99e-2)" "unprognostic (8.64e-2)" "unprognostic (9.14e-2)" "unprognostic (5.40e-2)" "unprognostic (4.65e-2)" "unprognostic (6.51e-2)" "unprognostic (5.64e-2)" "unprognostic (1.83e-1)" ZNF550 MGC41917 ENSG00000251369 "Zinc finger protein 550" 19 57535257-57559863 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Cardiomyocytes: 103.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003251 Uncertain Approved Vesicles,Microtubules NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 1 Vesicles Microtubules "HPA003251: " "unprognostic (3.87e-3)" "unprognostic (2.23e-1)" "unprognostic (3.00e-1)" "unprognostic (1.37e-1)" "unprognostic (1.78e-1)" "unprognostic (6.24e-3)" "unprognostic (1.58e-1)" "unprognostic (3.82e-1)" "unprognostic (1.68e-1)" "unprognostic (3.51e-3)" "unprognostic (2.95e-3)" "potential prognostic favorable (9.85e-4)" "potential prognostic favorable (5.12e-4)" "unprognostic (2.00e-2)" "unprognostic (5.93e-2)" "unprognostic (1.28e-1)" "unprognostic (1.31e-1)" "unprognostic (1.17e-1)" "unprognostic (2.15e-1)" "unprognostic (8.55e-2)" "unprognostic (1.41e-1)" "unprognostic (9.93e-2)" "unprognostic (6.67e-2)" "unprognostic (6.26e-3)" "unprognostic (3.15e-2)" "unprognostic (1.01e-2)" "unprognostic (4.65e-3)" "unprognostic (4.50e-2)" "unprognostic (3.18e-1)" "unprognostic (8.91e-3)" "unprognostic (8.70e-2)" ZNF551 DKFZp686H1038 ENSG00000204519 "Zinc finger protein 551" Q7Z340 19 57681969-57717301 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Early spermatids: 4.5;Late primary spermatocytes: 6.5;Late spermatids: 2.0;Thymocytes: 1.7" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" HPA038187 Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" "Nucleoplasm, Nuclear speckles" "HPA038187: " "unprognostic (8.48e-2)" "unprognostic (5.81e-2)" "unprognostic (1.05e-1)" "unprognostic (2.16e-2)" "unprognostic (7.38e-2)" "unprognostic (2.76e-1)" "unprognostic (1.04e-2)" "unprognostic (1.74e-1)" "unprognostic (2.71e-1)" "unprognostic (6.08e-3)" "potential prognostic favorable (6.30e-5)" "unprognostic (7.61e-3)" "unprognostic (4.32e-2)" "unprognostic (8.57e-2)" "unprognostic (2.19e-1)" "unprognostic (2.93e-1)" "unprognostic (6.25e-3)" "unprognostic (2.22e-2)" "unprognostic (2.59e-1)" "unprognostic (3.03e-1)" "unprognostic (4.10e-1)" "unprognostic (4.17e-2)" "unprognostic (5.57e-2)" "unprognostic (6.84e-3)" "unprognostic (1.86e-3)" "unprognostic (1.72e-1)" "potential prognostic unfavorable (4.99e-4)" "unprognostic (8.99e-2)" "unprognostic (4.86e-1)" "unprognostic (2.29e-2)" "unprognostic (1.15e-1)" ZNF552 FLJ21603 ENSG00000178935 "Zinc finger protein 552" Q9H707 19 57803841-57814913 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 125.8;Prostatic club cells: 221.0;Prostatic hillock cells: 261.7" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Breast Invasive Carcinoma (TCGA): 57.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 25.4" "Lineage enriched" "Detected in all" 6 "granulocytes: 25.4" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate basal glandular cells" "HPA043800, HPA053762, HPA072145" Uncertain Uncertain Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 48: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" 31 Nucleoplasm "HPA043800: , HPA053762: , HPA072145: " "unprognostic (1.37e-3)" "unprognostic (8.99e-3)" "unprognostic (1.29e-1)" "unprognostic (9.60e-2)" "unprognostic (1.61e-1)" "unprognostic (9.78e-2)" "unprognostic (2.34e-1)" "unprognostic (3.12e-1)" "unprognostic (1.12e-3)" "unprognostic (2.54e-2)" "unprognostic (1.05e-1)" "potential prognostic favorable (8.14e-5)" "unprognostic (5.15e-3)" "unprognostic (1.15e-1)" "unprognostic (3.40e-1)" "potential prognostic favorable (4.23e-4)" "unprognostic (1.19e-1)" "unprognostic (7.54e-2)" "unprognostic (1.39e-1)" "unprognostic (2.03e-1)" "unprognostic (1.80e-1)" "unprognostic (1.12e-1)" "unprognostic (1.23e-1)" "unprognostic (2.06e-1)" "potential prognostic favorable (1.02e-4)" "unprognostic (4.01e-1)" "unprognostic (5.87e-2)" "unprognostic (1.94e-2)" "unprognostic (1.71e-1)" "unprognostic (4.88e-3)" "unprognostic (1.63e-2)" ZNF554 FLJ34817 ENSG00000172006 "Zinc finger protein 554" Q86TJ5 19 2819868-2836735 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 21.3;Syncytiotrophoblasts: 23.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "HPA060247, HPA063358" Uncertain Enhanced Nucleoplasm,Nucleoli No No "Cluster 2: Non-specific - Mixed function" "Cluster 24: Neurons - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 6 Nucleoplasm Nucleoli "HPA060247: , HPA063358: " "unprognostic (1.51e-2)" "unprognostic (7.22e-2)" "unprognostic (1.13e-1)" "unprognostic (7.60e-2)" "unprognostic (1.32e-1)" "unprognostic (8.76e-3)" "unprognostic (1.86e-1)" "unprognostic (2.85e-1)" "unprognostic (2.20e-1)" "unprognostic (9.38e-3)" "unprognostic (1.38e-2)" "unprognostic (8.18e-2)" "unprognostic (2.29e-2)" "unprognostic (1.58e-2)" "unprognostic (2.59e-1)" "unprognostic (2.12e-3)" "unprognostic (3.77e-2)" "unprognostic (5.60e-2)" "potential prognostic favorable (2.78e-5)" "unprognostic (1.41e-1)" "unprognostic (8.51e-2)" "unprognostic (3.41e-2)" "unprognostic (4.68e-2)" "unprognostic (3.55e-2)" "unprognostic (2.63e-1)" "unprognostic (4.23e-1)" "unprognostic (1.79e-1)" "unprognostic (2.63e-1)" ZNF555 MGC26707 ENSG00000186300 "Zinc finger protein 555" Q8NEP9 19 2841437-2860471 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 96.2;Late primary spermatocytes: 57.6;Late spermatids: 114.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "HPA053956, HPA055430" Uncertain NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 55: Myocytes - Oxidative muscle function" 6 "HPA053956: , HPA055430: " "unprognostic (4.07e-2)" "unprognostic (1.51e-1)" "unprognostic (2.45e-1)" "unprognostic (1.73e-1)" "unprognostic (8.26e-2)" "unprognostic (6.73e-2)" "unprognostic (1.50e-1)" "unprognostic (6.92e-2)" "unprognostic (4.84e-2)" "unprognostic (1.44e-1)" "potential prognostic favorable (6.24e-7)" "unprognostic (1.27e-3)" "unprognostic (3.46e-2)" "unprognostic (2.59e-1)" "unprognostic (3.73e-2)" "unprognostic (2.80e-2)" "unprognostic (4.31e-2)" "unprognostic (2.78e-1)" "unprognostic (5.01e-1)" "unprognostic (7.20e-2)" "potential prognostic unfavorable (1.22e-4)" "unprognostic (5.05e-2)" "unprognostic (1.77e-2)" "unprognostic (3.83e-2)" "unprognostic (6.63e-3)" "unprognostic (6.61e-2)" "unprognostic (1.96e-1)" "unprognostic (2.22e-1)" "unprognostic (3.40e-1)" "unprognostic (6.46e-2)" "unprognostic (1.86e-2)" ZNF556 FLJ11637 ENSG00000172000 "Zinc finger protein 556" Q9HAH1 19 2867335-2883445 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "ovary: 3.8;skeletal muscle: 2.3;tongue: 3.2" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 9.5;Epididymal clear cells: 28.6;Myonuclei: 46.7;Myosatellite cells: 13.8;Ovarian stromal cells: 15.5;pDCs: 29.0" "Group enriched" "Detected in many" 4 "central nervous system macrophage: 7.4;cerebellar inhibitory: 4.1;hippocampal CA4: 6.2;upper rhombic lip: 12.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 10 "plasmacytoid DC: 15.0" "Lineage enriched" "Detected in many" 10 "dendritic cells: 15.0" "Low cancer specificity" "Detected in some" "Adipose visceral - Mesothelial cells" HPA060593 Approved Nucleoplasm NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 48: Non-specific - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 55: Myocytes - Oxidative muscle function" Nucleoplasm "HPA060593: " "unprognostic (8.45e-2)" "unprognostic (1.09e-1)" "unprognostic (1.65e-1)" "unprognostic (3.43e-3)" "unprognostic (5.23e-2)" "unprognostic (1.22e-3)" "unprognostic (1.66e-1)" "unprognostic (7.78e-2)" "potential prognostic favorable (6.94e-4)" "unprognostic (3.26e-1)" "unprognostic (3.59e-2)" "unprognostic (1.32e-1)" "unprognostic (4.35e-2)" ZNF557 MGC4054 ENSG00000130544 "Zinc finger protein 557" Q8N988 19 7069703-7087968 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA003151, HPA029291" Uncertain Approved "Nucleoplasm,Intermediate filaments" No No "Cluster 3: Non-specific - Nuclear processes" "Cluster 61: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" "Nucleoplasm, Intermediate filaments" "HPA003151: , HPA029291: " "unprognostic (4.86e-3)" "unprognostic (1.28e-2)" "unprognostic (1.22e-2)" "unprognostic (1.79e-1)" "unprognostic (1.69e-1)" "unprognostic (1.25e-1)" "unprognostic (3.13e-2)" "unprognostic (1.49e-1)" "potential prognostic favorable (7.22e-7)" "unprognostic (6.68e-3)" "unprognostic (6.53e-3)" "potential prognostic favorable (2.43e-4)" "unprognostic (6.13e-2)" "unprognostic (1.20e-1)" "unprognostic (4.95e-2)" "unprognostic (1.32e-3)" "unprognostic (1.08e-1)" "unprognostic (9.55e-2)" "potential prognostic favorable (9.16e-5)" "unprognostic (1.88e-1)" "unprognostic (5.86e-2)" "unprognostic (2.07e-3)" "unprognostic (2.45e-1)" "unprognostic (4.07e-2)" "unprognostic (2.11e-3)" "unprognostic (9.16e-3)" "unprognostic (3.91e-2)" "unprognostic (1.94e-2)" "unprognostic (1.59e-1)" "unprognostic (1.66e-1)" "unprognostic (6.81e-2)" ZNF558 FLJ30932 ENSG00000167785 "Zinc finger protein 558" Q96NG5 19 8806170-8832314 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003151 Uncertain NA NA "Cluster 24: Non-specific - Transcription" "Cluster 75: Ovary - Mixed function" "Cluster 55: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 13 "HPA003151: " "unprognostic (7.56e-3)" "unprognostic (5.94e-3)" "unprognostic (3.95e-2)" "unprognostic (1.23e-1)" "unprognostic (1.99e-1)" "unprognostic (1.21e-1)" "unprognostic (4.25e-1)" "unprognostic (2.50e-1)" "potential prognostic favorable (9.51e-5)" "unprognostic (1.90e-3)" "unprognostic (3.48e-2)" "unprognostic (1.45e-1)" "unprognostic (9.60e-3)" "unprognostic (2.39e-2)" "unprognostic (4.56e-2)" "unprognostic (3.16e-1)" "unprognostic (9.70e-3)" "unprognostic (7.50e-2)" "unprognostic (1.98e-2)" "unprognostic (8.04e-3)" "unprognostic (2.76e-1)" "unprognostic (6.26e-2)" "unprognostic (7.37e-2)" "unprognostic (7.38e-2)" "unprognostic (3.40e-3)" "unprognostic (1.08e-2)" "unprognostic (5.43e-2)" "unprognostic (4.03e-3)" "unprognostic (1.51e-1)" "unprognostic (3.71e-2)" "unprognostic (1.04e-1)" ZNF559 MGC13105 ENSG00000188321 "Zinc finger protein 559" Q9BR84 19 9323772-9351162 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 10 "Astrocytes: 44.4;Bergmann glia: 65.4;Brain excitatory neurons: 44.9;Brain inhibitory neurons: 38.5;Choroid plexus epithelial cells: 54.1;Ependymal cells: 43.0;Microglia: 46.6;Oligodendrocyte progenitor cells: 47.2;Oligodendrocytes: 47.7;Other brain neurons: 45.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - T-cells" "HPA059632, HPA065485" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 21: Testis - Mixed function" "Cluster 25: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 22: Non-specific - Basic cellular functions" 15 Nucleoplasm Cytosol "HPA059632: , HPA065485: " "unprognostic (1.72e-3)" "unprognostic (1.08e-3)" "unprognostic (4.31e-2)" "unprognostic (5.87e-2)" "unprognostic (5.47e-2)" "unprognostic (3.19e-1)" "unprognostic (3.75e-2)" "unprognostic (7.79e-2)" "unprognostic (1.73e-2)" "unprognostic (3.67e-2)" "unprognostic (9.83e-3)" "potential prognostic favorable (3.86e-4)" "unprognostic (6.34e-3)" "unprognostic (1.53e-1)" "unprognostic (2.23e-2)" "unprognostic (3.22e-1)" "unprognostic (1.22e-1)" "unprognostic (1.33e-1)" "unprognostic (5.04e-2)" "unprognostic (1.57e-2)" "unprognostic (1.55e-2)" "unprognostic (1.11e-2)" "unprognostic (2.16e-2)" "unprognostic (1.37e-1)" "unprognostic (1.98e-1)" "unprognostic (1.03e-1)" "potential prognostic unfavorable (2.48e-5)" "unprognostic (4.18e-2)" "unprognostic (4.32e-2)" "unprognostic (2.02e-1)" "unprognostic (2.18e-1)" ZNF559-ZNF177 ENSG00000270011 "ZNF559-ZNF177 readthrough" 19 9324174-9382617 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "retina: 4.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 29.4;Distal convoluted tubule cells: 32.5;Pituitary stem cells: 30.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" HPA003141 Approved NA NA "Cluster 32: Basophils - Transcription" "Cluster 65: Brain - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" "HPA003141: " "unprognostic (1.89e-1)" "unprognostic (3.49e-1)" "unprognostic (4.74e-2)" "unprognostic (1.33e-1)" "unprognostic (1.32e-1)" "unprognostic (2.95e-2)" "unprognostic (2.11e-3)" "unprognostic (1.14e-1)" "unprognostic (1.96e-1)" "unprognostic (3.89e-2)" ZNF560 FLJ31986 ENSG00000198028 "Zinc finger protein 560" Q96MR9 19 9466355-9498616 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "retina: 1.9;testis: 5.8" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 18.3;Early primary spermatocytes: 22.7;Early spermatids: 62.4;Late primary spermatocytes: 85.9;Late spermatids: 16.7;Oocytes: 50.7;Rod photoreceptor cells: 12.5;Sertoli cells: 22.5;Undifferentiated spermatogonia: 14.1" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 10 "Testicular Germ Cell Tumor (TCGA): 12.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Adrenocortical cancer: 7.2;testis cancer: 8.5" "HPA045439, HPA074438" Enhanced "Nucleoplasm,Nuclear speckles" NA NA "Cluster 47: Testis - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" Nucleoplasm "Nuclear speckles" "HPA045439: , HPA074438: " "unprognostic (5.14e-3)" "potential prognostic favorable (1.08e-5)" "unprognostic (4.31e-2)" "unprognostic (6.43e-2)" "unprognostic (9.16e-3)" "unprognostic (1.72e-1)" ZNF561 MGC45408 ENSG00000171469 "Zinc finger protein 561" Q8N587 19 9604680-9621236 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 118.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA055332, HPA062397" Uncertain Approved Nucleoplasm NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 23: Non-specific - Transcription" "Cluster 100: Stratified epithelial cells - Barrier functions" 5 Nucleoplasm "HPA055332: , HPA062397: " "unprognostic (7.76e-3)" "unprognostic (1.47e-1)" "unprognostic (3.01e-1)" "unprognostic (2.38e-1)" "unprognostic (2.41e-2)" "unprognostic (1.59e-1)" "unprognostic (3.54e-2)" "unprognostic (2.26e-1)" "unprognostic (3.32e-3)" "potential prognostic unfavorable (9.42e-4)" "potential prognostic favorable (1.53e-6)" "unprognostic (1.54e-3)" "unprognostic (6.41e-2)" "unprognostic (8.01e-2)" "unprognostic (1.04e-1)" "unprognostic (1.19e-1)" "unprognostic (2.08e-1)" "unprognostic (4.02e-1)" "unprognostic (5.06e-2)" "unprognostic (4.09e-2)" "unprognostic (3.36e-2)" "unprognostic (2.02e-1)" "unprognostic (3.48e-3)" "unprognostic (1.73e-1)" "unprognostic (1.13e-3)" "unprognostic (3.36e-1)" "unprognostic (7.59e-2)" "unprognostic (1.82e-1)" "unprognostic (3.64e-1)" "unprognostic (5.52e-2)" "unprognostic (3.10e-2)" ZNF562 FLJ20079 ENSG00000171466 "Zinc finger protein 562" Q6V9R5 19 9641807-9675100 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 192.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells" "HPA055332, HPA062397" Uncertain Approved Nucleoplasm NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 23: Non-specific - Transcription" "Cluster 69: Urothelial cells - Basic cellular functions" 6 Nucleoplasm "HPA055332: , HPA062397: " "unprognostic (7.37e-3)" "unprognostic (1.45e-1)" "unprognostic (1.84e-1)" "unprognostic (2.08e-2)" "unprognostic (1.81e-1)" "unprognostic (2.02e-1)" "unprognostic (4.09e-2)" "unprognostic (2.92e-2)" "unprognostic (1.09e-3)" "potential prognostic unfavorable (6.24e-5)" "potential prognostic favorable (2.26e-4)" "unprognostic (1.52e-3)" "unprognostic (7.23e-2)" "unprognostic (2.08e-1)" "unprognostic (1.07e-1)" "unprognostic (5.03e-2)" "unprognostic (1.13e-2)" "unprognostic (4.60e-2)" "unprognostic (6.90e-2)" "unprognostic (8.62e-2)" "unprognostic (3.96e-2)" "unprognostic (6.31e-2)" "unprognostic (4.76e-2)" "unprognostic (1.50e-1)" "potential prognostic favorable (5.43e-4)" "unprognostic (1.24e-1)" "unprognostic (4.54e-2)" "unprognostic (1.10e-1)" "unprognostic (3.40e-1)" "unprognostic (2.29e-2)" "unprognostic (3.02e-1)" ZNF563 FLJ34797 ENSG00000188868 "Zinc finger protein 563" Q8TA94 19 12317477-12333720 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 13.5" "Cell type enhanced" "Detected in many" "Early spermatids: 183.9;Late primary spermatocytes: 156.0;Müller glia: 42.6;Sertoli cells: 49.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 4.2;T-cells: 8.9" "Low cancer specificity" "Detected in many" "Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" HPA042136 Uncertain Approved Vesicles NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 47: Testis - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 1 Vesicles "HPA042136: " "potential prognostic favorable (3.44e-4)" "unprognostic (1.72e-2)" "unprognostic (5.11e-3)" "unprognostic (1.02e-1)" "unprognostic (2.18e-1)" "unprognostic (1.83e-2)" "unprognostic (1.49e-1)" "unprognostic (7.86e-2)" "unprognostic (2.52e-1)" "unprognostic (5.54e-3)" "validated prognostic favorable (1.11e-5)" "validated prognostic favorable (7.65e-4)" "potential prognostic favorable (5.77e-4)" "unprognostic (4.35e-2)" "unprognostic (7.88e-3)" "unprognostic (1.47e-2)" "unprognostic (2.02e-1)" "unprognostic (1.83e-1)" "unprognostic (2.05e-1)" "unprognostic (2.11e-1)" "unprognostic (2.15e-2)" "unprognostic (1.94e-1)" "unprognostic (3.39e-1)" "unprognostic (5.24e-1)" "unprognostic (4.26e-2)" "unprognostic (5.23e-3)" "unprognostic (1.07e-2)" "unprognostic (5.88e-2)" "unprognostic (5.75e-1)" "unprognostic (1.86e-1)" "unprognostic (5.65e-2)" ZNF564 MGC26914 ENSG00000249709 "Zinc finger protein 564" Q8TBZ8 19 12525373-12551542 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Myosatellite cells: 2.3;Respiratory deuterosomal cells: 1.0" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA043998 Uncertain Approved "Golgi apparatus" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 33: Thyroid gland - Tissue development" "Cluster 35: Non-specific - DNA binding" "Cluster 4: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 36 "Golgi apparatus" "HPA043998: " "unprognostic (1.92e-2)" "unprognostic (7.83e-2)" "unprognostic (2.06e-1)" "unprognostic (5.84e-2)" "unprognostic (1.08e-2)" "unprognostic (2.04e-2)" "unprognostic (4.44e-2)" "unprognostic (4.20e-3)" "unprognostic (6.97e-3)" "unprognostic (4.15e-2)" "validated prognostic favorable (5.05e-7)" "validated prognostic favorable (1.45e-4)" "unprognostic (1.48e-3)" "unprognostic (2.75e-1)" "unprognostic (8.66e-3)" "unprognostic (2.13e-3)" "unprognostic (1.48e-1)" "unprognostic (1.70e-1)" "unprognostic (1.99e-2)" "unprognostic (5.11e-3)" "unprognostic (4.17e-2)" "unprognostic (2.40e-2)" "unprognostic (1.67e-2)" "unprognostic (2.00e-1)" "unprognostic (7.20e-3)" "unprognostic (3.70e-1)" "unprognostic (2.86e-2)" "unprognostic (1.09e-2)" "unprognostic (1.94e-1)" "unprognostic (6.30e-2)" "unprognostic (2.58e-1)" ZNF565 FLJ36991 ENSG00000196357 "Zinc finger protein 565" Q8N9K5 19 36182276-36246257 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 509.1;Epicardial cells: 338.8;Myonuclei: 307.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 16.3" "Lineage enriched" "Detected in all" 5 "granulocytes: 16.3" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" HPA044123 Uncertain Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 1 "Nucleoplasm, Nuclear bodies" "HPA044123: " "unprognostic (5.19e-2)" "unprognostic (9.71e-3)" "unprognostic (1.04e-1)" "unprognostic (8.75e-2)" "unprognostic (5.13e-2)" "unprognostic (4.72e-2)" "unprognostic (3.84e-2)" "unprognostic (1.12e-1)" "unprognostic (1.43e-2)" "unprognostic (6.46e-3)" "unprognostic (1.38e-2)" "unprognostic (3.04e-1)" "unprognostic (1.04e-1)" "unprognostic (2.03e-2)" "unprognostic (5.49e-3)" "unprognostic (4.40e-2)" "unprognostic (4.05e-1)" "unprognostic (2.19e-3)" "unprognostic (1.51e-1)" "unprognostic (1.65e-2)" "unprognostic (1.06e-1)" "unprognostic (1.09e-2)" "unprognostic (2.78e-1)" "unprognostic (1.66e-2)" "potential prognostic favorable (4.03e-5)" "unprognostic (3.20e-2)" "unprognostic (1.86e-3)" "unprognostic (2.10e-1)" "unprognostic (1.79e-1)" "unprognostic (1.69e-3)" "unprognostic (2.93e-1)" ZNF566 "FLJ14779, MGC12515" ENSG00000186017 "Zinc finger protein 566" Q969W8 19 36445119-36489902 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023456 Uncertain Approved Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 8 Nucleoplasm "HPA023456: " "unprognostic (2.29e-2)" "unprognostic (1.03e-1)" "unprognostic (3.86e-1)" "unprognostic (2.10e-2)" "unprognostic (8.97e-3)" "unprognostic (2.51e-2)" "unprognostic (1.19e-1)" "unprognostic (3.37e-1)" "unprognostic (1.44e-3)" "unprognostic (5.23e-2)" "unprognostic (3.98e-2)" "unprognostic (6.33e-3)" "unprognostic (1.77e-3)" "unprognostic (1.16e-1)" "unprognostic (1.04e-1)" "unprognostic (1.40e-1)" "unprognostic (3.30e-2)" "unprognostic (8.07e-2)" "unprognostic (1.04e-1)" "unprognostic (3.23e-1)" "unprognostic (2.28e-2)" "potential prognostic favorable (2.84e-5)" "unprognostic (4.60e-3)" "unprognostic (4.08e-1)" "unprognostic (8.66e-2)" "unprognostic (2.68e-1)" "unprognostic (6.04e-2)" "unprognostic (3.20e-2)" "unprognostic (4.34e-2)" "unprognostic (1.74e-1)" "unprognostic (2.90e-1)" ZNF567 MGC45586 ENSG00000189042 "Zinc finger protein 567" Q8N184 19 36687612-36727701 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 106.1;Late spermatids: 177.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" HPA023937 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 5 Nucleoplasm Cytosol "HPA023937: " "potential prognostic favorable (9.57e-5)" "unprognostic (2.38e-3)" "unprognostic (8.99e-2)" "unprognostic (3.60e-2)" "unprognostic (1.34e-1)" "unprognostic (9.01e-2)" "unprognostic (1.86e-1)" "unprognostic (1.48e-1)" "unprognostic (4.92e-2)" "unprognostic (8.75e-2)" "unprognostic (3.80e-3)" "unprognostic (4.95e-3)" "unprognostic (1.49e-1)" "unprognostic (1.39e-2)" "unprognostic (3.67e-1)" "unprognostic (2.90e-2)" "unprognostic (3.94e-1)" "unprognostic (3.35e-3)" "unprognostic (1.94e-1)" "unprognostic (1.09e-1)" "unprognostic (8.93e-2)" "unprognostic (1.99e-1)" "potential prognostic unfavorable (4.12e-4)" "unprognostic (3.40e-1)" "unprognostic (1.14e-3)" "unprognostic (3.48e-1)" "unprognostic (1.64e-3)" "unprognostic (1.80e-2)" "unprognostic (3.27e-1)" "unprognostic (3.47e-2)" "unprognostic (7.36e-2)" ZNF568 DKFZp686B0797 ENSG00000198453 "Zinc finger protein 568" Q3ZCX4 19 36916316-37005037 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 35.8;Bergmann glia: 46.6;Brain excitatory neurons: 39.6;Brain inhibitory neurons: 39.2;Choroid plexus epithelial cells: 55.8;Distal convoluted tubule cells: 32.0;Oligodendrocyte progenitor cells: 48.3;Oligodendrocytes: 43.6;Other brain neurons: 44.5;Podocytes: 40.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Spleen - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "HPA024541, HPA052061" Uncertain Approved Nucleoplasm NA NA "Cluster 32: Basophils - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 102: Non-specific - Mixed function" Nucleoplasm "HPA024541: , HPA052061: " "unprognostic (1.11e-3)" "unprognostic (1.85e-1)" "unprognostic (8.85e-2)" "unprognostic (4.98e-2)" "unprognostic (2.54e-1)" "unprognostic (1.56e-1)" "unprognostic (2.24e-1)" "unprognostic (1.42e-2)" "unprognostic (3.73e-3)" "unprognostic (1.13e-1)" "validated prognostic favorable (6.11e-6)" "validated prognostic favorable (8.54e-5)" "unprognostic (3.07e-2)" "unprognostic (1.41e-1)" "unprognostic (1.52e-1)" "unprognostic (6.84e-2)" "unprognostic (2.37e-1)" "unprognostic (1.93e-1)" "unprognostic (3.81e-2)" "unprognostic (6.00e-2)" "unprognostic (1.95e-2)" "unprognostic (4.54e-2)" "unprognostic (4.01e-1)" "unprognostic (1.34e-1)" "unprognostic (2.00e-1)" "unprognostic (1.76e-1)" "potential prognostic unfavorable (2.90e-4)" "unprognostic (1.60e-2)" "unprognostic (1.49e-1)" "unprognostic (3.78e-2)" "unprognostic (2.24e-1)" ZNF569 "FLJ32053, ZAP1, Zfp74" ENSG00000196437 "Zinc finger protein 569" Q5MCW4 19 37411155-37469275 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 201.6;Late primary spermatocytes: 112.1;Rod photoreceptor cells: 78.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052994 Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 3 "Nucleoplasm, Golgi apparatus, Vesicles" "HPA052994: " "unprognostic (3.40e-3)" "unprognostic (3.73e-2)" "unprognostic (2.03e-1)" "unprognostic (1.48e-2)" "unprognostic (1.25e-1)" "unprognostic (4.16e-2)" "unprognostic (1.21e-1)" "unprognostic (2.71e-2)" "unprognostic (2.23e-2)" "potential prognostic favorable (1.98e-4)" "unprognostic (7.10e-3)" "unprognostic (5.25e-2)" "unprognostic (3.13e-3)" "unprognostic (3.19e-1)" "unprognostic (2.20e-1)" "unprognostic (3.27e-1)" "unprognostic (3.27e-2)" "unprognostic (1.24e-1)" "unprognostic (1.99e-1)" "unprognostic (5.76e-2)" "unprognostic (4.26e-3)" "unprognostic (6.02e-2)" "unprognostic (1.22e-1)" "unprognostic (4.91e-1)" "unprognostic (3.07e-2)" "unprognostic (3.38e-2)" "unprognostic (1.61e-1)" "unprognostic (4.82e-2)" "unprognostic (5.26e-3)" "unprognostic (1.50e-1)" ZNF57 ZNF424 ENSG00000171970 "Zinc finger protein 57" Q68EA5 19 2900928-2918473 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 25.0" "Cell type enhanced" "Detected in many" "Early spermatids: 87.9;Esophageal apical cells: 34.0;Late primary spermatocytes: 51.3;Late spermatids: 83.2;Oocytes: 138.2;Suprabasal keratinocytes: 34.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other), Stomach - Parietal cells, Testis - Early spermatids" "Low region specificity" "Detected in all" HPA061915 Approved Nucleoli NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 57: Testis - Spermatogenesis" "Cluster 35: Non-specific - DNA binding" "Cluster 4: Non-specific - Transcription" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 17 Nucleoli "HPA061915: " "unprognostic (2.16e-1)" "unprognostic (6.05e-2)" "unprognostic (7.77e-3)" "unprognostic (7.95e-2)" "unprognostic (1.02e-1)" "unprognostic (3.70e-2)" "unprognostic (5.24e-2)" "unprognostic (1.64e-2)" "unprognostic (3.19e-2)" "unprognostic (9.23e-2)" "potential prognostic favorable (1.05e-4)" "unprognostic (2.49e-2)" "potential prognostic favorable (1.23e-5)" "unprognostic (1.77e-1)" "unprognostic (5.46e-3)" "unprognostic (3.08e-2)" "unprognostic (9.02e-2)" "unprognostic (5.43e-2)" "unprognostic (1.04e-2)" "unprognostic (1.46e-1)" "unprognostic (3.41e-1)" "unprognostic (1.08e-1)" "unprognostic (8.55e-2)" "unprognostic (1.64e-3)" "unprognostic (1.36e-3)" "unprognostic (2.73e-1)" "unprognostic (2.58e-2)" "unprognostic (5.94e-2)" "unprognostic (2.39e-1)" "unprognostic (3.93e-2)" "unprognostic (5.52e-2)" ZNF570 FLJ30791 ENSG00000171827 "Zinc finger protein 570" Q96NI8 19 37467585-37488652 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 67.8;Late primary spermatocytes: 36.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028881 Uncertain Approved Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" Nucleoplasm "HPA028881: " "unprognostic (2.55e-3)" "unprognostic (8.99e-2)" "unprognostic (1.95e-1)" "unprognostic (7.88e-2)" "unprognostic (7.81e-2)" "unprognostic (4.99e-2)" "unprognostic (3.91e-2)" "unprognostic (1.18e-2)" "unprognostic (1.10e-1)" "validated prognostic favorable (8.43e-6)" "validated prognostic favorable (2.05e-4)" "unprognostic (9.68e-3)" "unprognostic (4.50e-2)" "unprognostic (2.30e-2)" "unprognostic (3.32e-2)" "unprognostic (9.24e-2)" "unprognostic (2.02e-1)" "unprognostic (2.11e-1)" "unprognostic (2.28e-2)" "unprognostic (3.72e-2)" "unprognostic (3.49e-1)" "unprognostic (2.90e-2)" "unprognostic (7.68e-2)" "unprognostic (7.79e-2)" "unprognostic (4.04e-2)" "unprognostic (9.69e-2)" "unprognostic (5.98e-2)" "unprognostic (1.38e-2)" "unprognostic (1.79e-1)" ZNF571 HSPC059 ENSG00000180479 "Zinc finger protein 571" Q7Z3V5 19 37554782-37594792 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 72.7" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 144.1;Lactotrophs: 98.5;Oocytes: 59.9;Rod photoreceptor cells: 78.3;Somatotrophs: 147.2;Thyrotrophs: 61.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 58.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA054762 Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 4: Non-specific - Transcription" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" "Nucleoplasm, Nucleoli" "Plasma membrane" "HPA054762: " "unprognostic (4.44e-3)" "unprognostic (5.40e-2)" "unprognostic (3.85e-1)" "unprognostic (9.43e-2)" "unprognostic (6.41e-2)" "unprognostic (1.15e-1)" "unprognostic (1.01e-1)" "unprognostic (1.13e-2)" "unprognostic (3.57e-2)" "unprognostic (2.39e-2)" "unprognostic (3.82e-3)" "potential prognostic favorable (4.41e-4)" "unprognostic (1.02e-1)" "unprognostic (1.93e-3)" "unprognostic (1.79e-1)" "unprognostic (5.01e-2)" "unprognostic (4.62e-2)" "unprognostic (5.79e-2)" "unprognostic (2.95e-1)" "unprognostic (1.32e-3)" "unprognostic (7.32e-2)" "unprognostic (2.63e-2)" "unprognostic (1.30e-1)" "unprognostic (1.07e-1)" "unprognostic (2.68e-3)" "unprognostic (1.64e-1)" "unprognostic (2.57e-2)" "unprognostic (6.26e-2)" "unprognostic (1.77e-1)" "unprognostic (1.47e-3)" "unprognostic (4.69e-2)" ZNF572 FLJ38002 ENSG00000180938 "Zinc finger protein 572" Q7Z3I7 8 124973295-124979389 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bergmann glia: 4.3;Megakaryocytes: 6.2;Tuft cells: 11.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" HPA066838 Approved Approved "Nuclear speckles" NA NA "Cluster 61: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 95: Tuft cells - Chemosensory signaling" 58 "Nuclear speckles" "HPA066838: " "unprognostic (6.23e-2)" "unprognostic (1.32e-1)" "unprognostic (2.46e-1)" "unprognostic (1.35e-1)" "unprognostic (2.98e-1)" "unprognostic (2.38e-2)" "unprognostic (8.12e-3)" "potential prognostic favorable (3.75e-5)" "potential prognostic favorable (4.74e-4)" "unprognostic (8.00e-2)" "unprognostic (1.45e-2)" "unprognostic (1.14e-1)" "unprognostic (4.25e-2)" "unprognostic (4.99e-2)" "unprognostic (1.17e-1)" "unprognostic (2.13e-1)" "unprognostic (3.60e-1)" "unprognostic (9.95e-3)" "unprognostic (8.07e-2)" "unprognostic (4.42e-3)" "unprognostic (1.15e-1)" "unprognostic (6.09e-1)" "unprognostic (9.23e-2)" "unprognostic (1.10e-1)" "unprognostic (2.06e-1)" ZNF573 FLJ30921 ENSG00000189144 "Zinc finger protein 573" Q86YE8 19 37735833-37817300 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 221.4;Late spermatids: 452.4;Somatotrophs: 107.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" HPA042776 Uncertain Approved "Intermediate filaments,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 22: Epididymis - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 1 "Intermediate filaments" Cytosol "HPA042776: " "unprognostic (7.26e-3)" "unprognostic (8.14e-2)" "unprognostic (6.68e-2)" "unprognostic (9.40e-2)" "unprognostic (2.50e-1)" "unprognostic (2.15e-3)" "unprognostic (1.92e-1)" "unprognostic (1.26e-1)" "unprognostic (2.00e-3)" "unprognostic (3.00e-2)" "unprognostic (3.22e-2)" "unprognostic (2.64e-1)" "unprognostic (3.10e-1)" ZNF574 FLJ22059 ENSG00000105732 "Zinc finger protein 574" Q6ZN55 19 42068477-42081552 "Essential proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 133.2;Late primary spermatocytes: 49.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023196, HPA057274" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 67: Testis - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 3: Early primary spermatocytes - Early meiosis" 3 Nucleoplasm Vesicles "HPA023196: , HPA057274: " "unprognostic (3.98e-3)" "unprognostic (1.03e-1)" "unprognostic (3.65e-1)" "unprognostic (3.36e-3)" "unprognostic (9.87e-2)" "unprognostic (9.90e-2)" "unprognostic (2.09e-1)" "unprognostic (8.97e-2)" "unprognostic (7.31e-2)" "unprognostic (3.01e-1)" "unprognostic (2.42e-3)" "unprognostic (2.77e-2)" "unprognostic (1.53e-1)" "unprognostic (5.60e-2)" "unprognostic (1.94e-2)" "unprognostic (1.99e-3)" "unprognostic (6.15e-2)" "unprognostic (1.04e-2)" "unprognostic (1.45e-1)" "unprognostic (3.65e-3)" "unprognostic (1.48e-1)" "unprognostic (9.89e-2)" "unprognostic (6.72e-2)" "unprognostic (2.06e-1)" "unprognostic (3.52e-2)" "unprognostic (2.54e-1)" "unprognostic (7.49e-2)" "unprognostic (3.79e-1)" "unprognostic (1.72e-1)" "unprognostic (7.51e-2)" "unprognostic (8.36e-2)" ZNF575 FLJ32567 ENSG00000176472 "Zinc finger protein 575" Q86XF7 19 43525497-43536130 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 13.2;Colonocytes: 31.1;Epicardial cells: 13.6;Paneth cells: 15.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Prostate - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051865 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 59: Leukemia - T-cell receptor" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 23 Nucleoplasm "Nucleoli fibrillar center, Cytosol" "HPA051865: " "unprognostic (2.27e-1)" "unprognostic (1.24e-2)" "unprognostic (2.75e-2)" "unprognostic (9.94e-2)" "unprognostic (6.43e-2)" "unprognostic (2.62e-2)" "unprognostic (4.74e-2)" "unprognostic (2.74e-3)" "unprognostic (3.33e-1)" "unprognostic (6.98e-2)" "unprognostic (2.31e-1)" "unprognostic (6.73e-2)" "unprognostic (4.29e-2)" "unprognostic (9.48e-3)" "unprognostic (1.42e-1)" "unprognostic (1.32e-1)" "unprognostic (5.11e-2)" "potential prognostic favorable (4.06e-4)" "unprognostic (1.13e-1)" "unprognostic (5.60e-2)" "unprognostic (5.54e-2)" "unprognostic (1.31e-2)" "unprognostic (8.09e-2)" "unprognostic (3.29e-1)" "unprognostic (5.42e-3)" "unprognostic (4.71e-2)" ZNF576 MGC2508 ENSG00000124444 "Zinc finger protein 576" Q9H609 19 43596392-43601157 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Kupffer cells: 1.0;Late spermatids: 2.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050064 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 24: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 4: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 11 "Nucleoplasm, Golgi apparatus" "HPA050064: " "unprognostic (1.59e-1)" "unprognostic (2.64e-1)" "unprognostic (2.48e-1)" "unprognostic (5.12e-2)" "unprognostic (8.79e-2)" "unprognostic (7.05e-3)" "unprognostic (1.09e-1)" "unprognostic (3.18e-1)" "unprognostic (6.45e-2)" "unprognostic (1.23e-2)" "potential prognostic favorable (2.96e-5)" "unprognostic (8.17e-2)" "unprognostic (1.00e-1)" "potential prognostic unfavorable (1.50e-6)" "unprognostic (5.07e-2)" "unprognostic (2.75e-3)" "unprognostic (4.64e-2)" "unprognostic (1.12e-3)" "unprognostic (1.91e-1)" "unprognostic (1.32e-1)" "unprognostic (3.29e-2)" "unprognostic (3.36e-2)" "unprognostic (7.59e-2)" "unprognostic (2.10e-1)" "unprognostic (6.07e-2)" "unprognostic (3.02e-2)" "unprognostic (4.96e-3)" "unprognostic (2.17e-2)" "unprognostic (4.27e-1)" "unprognostic (2.01e-1)" "unprognostic (3.10e-1)" ZNF577 MGC4400 ENSG00000161551 "Zinc finger protein 577" Q9BSK1 19 51804816-51890950 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 83.1;Late spermatids: 97.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041499, HPA046761" Uncertain Supported Nucleoplasm,Nucleoli NA NA "Cluster 41: Basophils - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 11: White matter - Signal transduction" "Cluster 60: Prostate cancer - Unknown function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 1 "Nucleoplasm, Nucleoli" "HPA041499: , HPA046761: " "unprognostic (1.21e-2)" "unprognostic (2.19e-1)" "unprognostic (1.85e-1)" "unprognostic (4.69e-3)" "unprognostic (5.14e-2)" "unprognostic (2.67e-1)" "unprognostic (5.67e-2)" "unprognostic (5.97e-2)" "unprognostic (1.34e-2)" "unprognostic (6.98e-3)" "validated prognostic favorable (5.30e-5)" "validated prognostic favorable (5.32e-8)" "unprognostic (3.27e-2)" "unprognostic (2.76e-1)" "unprognostic (1.26e-1)" "unprognostic (1.52e-1)" "unprognostic (1.66e-1)" "unprognostic (9.45e-2)" "unprognostic (1.21e-1)" "unprognostic (1.42e-1)" "unprognostic (1.32e-1)" "unprognostic (1.57e-1)" "unprognostic (1.09e-2)" "unprognostic (6.81e-2)" "unprognostic (2.54e-2)" "unprognostic (1.74e-1)" "unprognostic (2.40e-2)" "unprognostic (3.97e-3)" "unprognostic (1.67e-1)" "unprognostic (7.66e-2)" "unprognostic (2.39e-1)" ZNF578 FLJ31384 ENSG00000258405 "Zinc finger protein 578" Q96N58 19 52453553-52516882 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 5.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 26.9;Differentiating spermatogonia: 22.3;Early spermatids: 76.7;Late primary spermatocytes: 35.6;Late spermatids: 61.1;Rod photoreceptor cells: 20.5;Undifferentiated spermatogonia: 32.4" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 8 "Testicular Germ Cell Tumor (TCGA): 20.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 25: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 12 "unprognostic (7.31e-3)" "unprognostic (6.23e-2)" "unprognostic (5.56e-2)" "unprognostic (6.53e-2)" "unprognostic (1.66e-1)" "unprognostic (6.23e-3)" "unprognostic (1.37e-1)" "unprognostic (4.23e-2)" "potential prognostic favorable (1.96e-5)" "unprognostic (5.98e-3)" "unprognostic (1.68e-1)" "unprognostic (1.09e-2)" "unprognostic (1.96e-2)" "unprognostic (5.17e-2)" "unprognostic (4.05e-3)" "unprognostic (5.16e-2)" "unprognostic (1.58e-2)" "unprognostic (1.18e-1)" "unprognostic (5.11e-2)" "unprognostic (1.13e-1)" "unprognostic (2.37e-1)" "unprognostic (2.55e-2)" "unprognostic (3.12e-1)" ZNF579 FLJ35453 ENSG00000218891 "Zinc finger protein 579" Q8NAF0 19 55576774-55580848 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA062812 Approved Approved Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 72: Neuronal - Signal transduction" "Cluster 17: Non-specific - RNA processing" 6 Nucleoplasm "HPA062812: " "unprognostic (1.06e-3)" "unprognostic (1.10e-1)" "unprognostic (3.15e-2)" "unprognostic (2.14e-2)" "unprognostic (9.12e-2)" "unprognostic (2.12e-1)" "unprognostic (3.28e-1)" "unprognostic (1.64e-1)" "unprognostic (1.17e-1)" "unprognostic (2.43e-1)" "potential prognostic unfavorable (6.19e-5)" "unprognostic (1.61e-1)" "unprognostic (3.15e-1)" "unprognostic (1.75e-3)" "unprognostic (2.07e-2)" "unprognostic (5.85e-2)" "unprognostic (4.71e-2)" "unprognostic (2.66e-1)" "unprognostic (1.10e-2)" "unprognostic (1.59e-1)" "unprognostic (1.70e-1)" "unprognostic (2.30e-3)" "unprognostic (1.92e-1)" "unprognostic (9.54e-3)" "unprognostic (5.09e-2)" "unprognostic (1.95e-1)" "unprognostic (9.38e-2)" "unprognostic (2.71e-1)" "unprognostic (3.75e-1)" "unprognostic (7.80e-2)" "unprognostic (2.40e-1)" ZNF580 ENSG00000213015 "Zinc finger protein 580" Q9UK33 19 55635016-55643470 "Predicted intracellular proteins, Transcription factors" "Chemotaxis, Inflammatory response, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 8.8;Hematopoietic stem cells: 6.3;Parietal cells: 5.3;Tuft cells: 11.5" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054058 Approved Approved Nucleoplasm NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 89: Adipocytes - Lipid metabolism" 15 Nucleoplasm "HPA054058: " "potential prognostic favorable (9.34e-4)" "unprognostic (1.34e-1)" "unprognostic (7.91e-3)" "unprognostic (2.17e-2)" "unprognostic (1.03e-2)" "unprognostic (9.55e-3)" "unprognostic (3.76e-3)" "unprognostic (1.26e-1)" "unprognostic (1.78e-1)" "unprognostic (2.35e-1)" "unprognostic (1.19e-3)" "unprognostic (1.47e-2)" "unprognostic (2.72e-2)" "potential prognostic unfavorable (2.43e-4)" "unprognostic (3.07e-2)" "unprognostic (1.30e-1)" "unprognostic (2.18e-1)" "unprognostic (4.38e-2)" "unprognostic (3.92e-2)" "unprognostic (6.62e-2)" "unprognostic (1.04e-1)" "potential prognostic favorable (3.47e-5)" "unprognostic (2.14e-2)" "unprognostic (9.32e-2)" "unprognostic (7.83e-2)" "unprognostic (9.09e-3)" "unprognostic (1.29e-1)" "unprognostic (9.13e-2)" "unprognostic (2.31e-1)" "unprognostic (6.84e-2)" "unprognostic (6.08e-2)" ZNF581 "FLJ22550, HSPC189" ENSG00000171425 "Zinc finger protein 581" Q9P0T4 19 55635459-55645623 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004095, HPA059657" Uncertain Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 32: Basophils - Transcription" "Cluster 54: Non-specific - Ribosome" "Cluster 25: Non-specific - Transcription" "Cluster 25: Non-specific - Ribosome" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 92 "Nucleoplasm, Vesicles" Cytosol "HPA004095: , HPA059657: " "unprognostic (3.19e-2)" "unprognostic (5.85e-2)" "unprognostic (1.28e-1)" "unprognostic (1.93e-2)" "unprognostic (2.61e-1)" "unprognostic (1.54e-2)" "potential prognostic favorable (1.91e-4)" "unprognostic (1.38e-1)" "unprognostic (1.12e-2)" "unprognostic (2.25e-1)" "unprognostic (1.40e-2)" "unprognostic (5.85e-2)" "unprognostic (3.46e-1)" "potential prognostic unfavorable (6.28e-6)" "unprognostic (3.36e-3)" "unprognostic (2.64e-3)" "unprognostic (4.30e-2)" "unprognostic (1.08e-2)" "unprognostic (3.61e-1)" "unprognostic (1.24e-1)" "unprognostic (2.86e-1)" "unprognostic (2.83e-1)" "unprognostic (7.98e-2)" "unprognostic (3.73e-1)" "unprognostic (3.19e-2)" "unprognostic (9.64e-2)" "unprognostic (1.24e-1)" "unprognostic (1.38e-1)" "unprognostic (2.73e-1)" "unprognostic (1.66e-1)" "unprognostic (3.37e-2)" ZNF582 FLJ30927 ENSG00000018869 "Zinc finger protein 582" Q96NG8 19 56375846-56393538 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 31.5;Epicardial cells: 31.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028858 Uncertain Approved Nucleoplasm,Cytosol No No "Cluster 22: Eosinophils - Transcription" "Cluster 65: Brain - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 1 Cytosol Nucleoplasm "HPA028858: " "unprognostic (6.09e-2)" "unprognostic (3.91e-2)" "unprognostic (1.36e-1)" "unprognostic (2.75e-2)" "unprognostic (1.99e-2)" "unprognostic (3.71e-2)" "unprognostic (1.36e-1)" "validated prognostic favorable (7.91e-6)" "validated prognostic favorable (3.30e-4)" "unprognostic (1.55e-2)" "unprognostic (2.28e-3)" "unprognostic (3.13e-2)" "unprognostic (4.84e-2)" "unprognostic (3.81e-2)" "unprognostic (5.20e-2)" "unprognostic (3.38e-2)" "unprognostic (1.76e-1)" "unprognostic (1.56e-1)" "potential prognostic favorable (9.87e-5)" "unprognostic (4.09e-2)" "unprognostic (2.85e-2)" "unprognostic (1.02e-1)" "unprognostic (7.25e-3)" "unprognostic (4.05e-2)" "unprognostic (1.47e-1)" "unprognostic (1.32e-1)" ZNF583 FLJ31030 ENSG00000198440 "Zinc finger protein 583" Q96ND8 19 56397966-56436035 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 36.7;Early spermatids: 65.7;Late primary spermatocytes: 45.2;Late spermatids: 52.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023805, HPA023957" Uncertain Approved Nucleoli,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 16: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 35: Neurons - Synaptic function & neurogenesis" 1 Nucleoli Cytosol "HPA023805: , HPA023957: " "unprognostic (1.49e-2)" "unprognostic (1.07e-1)" "unprognostic (2.08e-1)" "unprognostic (9.68e-2)" "unprognostic (3.05e-2)" "unprognostic (3.52e-1)" "unprognostic (4.19e-2)" "unprognostic (1.31e-2)" "validated prognostic favorable (1.27e-7)" "validated prognostic favorable (2.76e-5)" "unprognostic (3.64e-3)" "unprognostic (3.67e-1)" "unprognostic (2.81e-2)" "unprognostic (8.02e-2)" "unprognostic (5.71e-2)" "unprognostic (3.12e-2)" "unprognostic (1.29e-1)" "unprognostic (1.27e-1)" "unprognostic (1.64e-1)" "unprognostic (7.80e-3)" "unprognostic (1.20e-1)" "unprognostic (2.78e-2)" "unprognostic (3.96e-2)" "unprognostic (1.63e-1)" "unprognostic (3.99e-3)" "unprognostic (1.33e-2)" "unprognostic (1.72e-1)" "unprognostic (2.11e-2)" "unprognostic (4.24e-2)" ZNF584 FLJ39899 ENSG00000171574 "Zinc finger protein 584" Q8IVC4 19 58401504-58431736 "Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 53.7;Respiratory ciliated cells: 78.2" "Cell type enhanced" "Detected in all" "ependymal cell: 49.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043408, HPA048075" Uncertain Approved "Nuclear speckles" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 24: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 107: Ciliated cells - Cilia assembly & function" 1 "Nuclear speckles" "HPA043408: , HPA048075: " "unprognostic (1.12e-1)" "unprognostic (2.45e-1)" "unprognostic (5.51e-2)" "unprognostic (1.37e-1)" "unprognostic (6.50e-3)" "unprognostic (1.61e-1)" "unprognostic (3.10e-1)" "unprognostic (2.94e-1)" "unprognostic (3.86e-2)" "unprognostic (3.16e-1)" "potential prognostic favorable (2.79e-5)" "unprognostic (3.75e-3)" "unprognostic (6.99e-2)" "unprognostic (9.53e-2)" "unprognostic (2.16e-1)" "unprognostic (3.36e-1)" "unprognostic (2.15e-2)" "unprognostic (3.11e-2)" "unprognostic (2.71e-1)" "unprognostic (1.27e-1)" "unprognostic (1.55e-1)" "unprognostic (2.66e-2)" "unprognostic (8.24e-3)" "unprognostic (8.30e-2)" "unprognostic (1.21e-1)" "unprognostic (6.76e-2)" "unprognostic (2.40e-2)" "unprognostic (3.54e-1)" "unprognostic (2.13e-1)" "unprognostic (3.23e-2)" "unprognostic (7.27e-3)" ZNF585A "FLJ23765, Zfp27" ENSG00000196967 "Zinc finger protein 585A" Q6P3V2 19 37106734-37172741 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 4.2;Early primary spermatocytes: 3.5;Early spermatids: 9.3;Gastric chief cells: 3.3;Late primary spermatocytes: 4.1;Late spermatids: 6.5;Tuft cells: 11.5" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 72: Kidney - Transmembrane transport" "Cluster 31: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" "unprognostic (1.30e-2)" "unprognostic (1.18e-2)" "unprognostic (7.72e-2)" "unprognostic (3.07e-1)" "unprognostic (9.62e-2)" "unprognostic (5.06e-2)" "unprognostic (8.11e-2)" "unprognostic (2.53e-1)" "unprognostic (1.42e-2)" "unprognostic (7.75e-2)" "unprognostic (7.12e-2)" "unprognostic (1.14e-1)" "unprognostic (1.08e-1)" "unprognostic (3.60e-3)" "unprognostic (5.52e-2)" "unprognostic (7.87e-2)" "unprognostic (7.56e-2)" "unprognostic (1.33e-1)" "unprognostic (3.14e-2)" "unprognostic (8.49e-2)" "unprognostic (1.23e-1)" "unprognostic (6.16e-3)" "unprognostic (1.15e-1)" "unprognostic (8.12e-2)" "unprognostic (2.09e-1)" "unprognostic (1.55e-1)" "unprognostic (1.17e-3)" "unprognostic (3.85e-3)" "unprognostic (2.87e-1)" "unprognostic (3.93e-2)" "unprognostic (2.55e-2)" ZNF585B "FLJ14928, SZFP41, Zfp27" ENSG00000245680 "Zinc finger protein 585B" Q52M93 19 37181579-37218153 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 14.8;Early spermatids: 15.5;Epididymal principal cells: 8.3;Tuft cells: 11.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" HPA075556 Approved "Nucleoplasm,Cytoplasmic bodies" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 65: Brain - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 1 "Nucleoplasm, Cytoplasmic bodies" "HPA075556: " "unprognostic (4.40e-2)" "unprognostic (8.13e-2)" "unprognostic (3.03e-1)" "unprognostic (1.76e-1)" "unprognostic (2.07e-1)" "unprognostic (1.54e-2)" "unprognostic (1.26e-1)" "unprognostic (5.96e-2)" "unprognostic (2.29e-1)" "unprognostic (3.38e-1)" "potential prognostic favorable (2.88e-4)" "unprognostic (1.37e-3)" "unprognostic (1.97e-3)" "unprognostic (5.16e-2)" "unprognostic (5.28e-1)" "unprognostic (2.57e-1)" "unprognostic (1.92e-1)" "unprognostic (7.97e-2)" "unprognostic (2.47e-2)" "unprognostic (5.23e-2)" "unprognostic (3.75e-2)" "unprognostic (2.32e-2)" "unprognostic (1.02e-1)" "unprognostic (1.58e-1)" "unprognostic (1.30e-1)" "unprognostic (6.88e-2)" "unprognostic (4.78e-3)" "unprognostic (4.06e-1)" "unprognostic (2.85e-1)" "unprognostic (5.07e-2)" "unprognostic (4.77e-1)" ZNF586 FLJ20070 ENSG00000083828 "Zinc finger protein 586" Q9NXT0 19 57769655-57819939 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 250.0;Neutrophils: 308.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "HPA030306, HPA060782" Approved Approved "Nucleoli fibrillar center,Vesicles" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 15: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 24: Neutrophils - Innate immunity signal integration" "Nucleoli fibrillar center" Vesicles "HPA030306: , HPA060782: " "unprognostic (1.80e-2)" "unprognostic (2.30e-2)" "unprognostic (2.84e-2)" "unprognostic (1.58e-2)" "unprognostic (2.84e-1)" "potential prognostic favorable (1.48e-4)" "unprognostic (4.04e-2)" "unprognostic (1.05e-1)" "unprognostic (3.25e-2)" "unprognostic (6.70e-3)" "potential prognostic favorable (6.72e-4)" "unprognostic (3.62e-3)" "unprognostic (2.75e-1)" "unprognostic (2.18e-3)" "unprognostic (6.18e-2)" "unprognostic (6.38e-3)" "unprognostic (2.49e-2)" "unprognostic (8.78e-2)" "unprognostic (8.21e-2)" "unprognostic (1.60e-1)" "unprognostic (2.43e-1)" "unprognostic (4.32e-1)" "unprognostic (9.24e-3)" "unprognostic (2.48e-2)" "unprognostic (2.69e-3)" "unprognostic (7.94e-2)" "potential prognostic unfavorable (8.71e-4)" "unprognostic (3.73e-1)" "unprognostic (1.74e-1)" "unprognostic (7.92e-2)" "unprognostic (3.59e-2)" ZNF587 "FLJ14710, FLJ20813, UBF-fl, ZF6" ENSG00000198466 "Zinc finger protein 587" Q96SQ5 19 57849859-57865117 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 69.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "HPA042125, HPA043288, HPA056213" Uncertain Approved Nucleoplasm,Nucleoli NA NA "Cluster 32: Basophils - Transcription" "Cluster 77: Intestine - Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 8: Non-specific - Secretory pathway" 102 Nucleoplasm Nucleoli "HPA042125: , HPA043288: , HPA056213: " "unprognostic (2.59e-2)" "unprognostic (7.18e-3)" "unprognostic (1.44e-1)" "unprognostic (6.79e-3)" "unprognostic (1.56e-1)" "unprognostic (1.09e-1)" "unprognostic (2.69e-1)" "unprognostic (7.51e-2)" "unprognostic (5.00e-2)" "unprognostic (8.94e-2)" "unprognostic (7.23e-3)" "unprognostic (2.21e-1)" "unprognostic (1.79e-1)" "unprognostic (8.80e-3)" "unprognostic (2.05e-1)" "unprognostic (2.92e-1)" "unprognostic (3.99e-2)" "unprognostic (3.04e-1)" "unprognostic (8.19e-2)" "unprognostic (1.42e-1)" "unprognostic (1.13e-1)" "unprognostic (1.51e-1)" "unprognostic (1.41e-1)" "unprognostic (8.68e-2)" "potential prognostic favorable (3.24e-4)" "unprognostic (1.09e-1)" "unprognostic (2.55e-3)" "unprognostic (1.67e-1)" "unprognostic (2.29e-1)" "unprognostic (8.83e-2)" "unprognostic (6.82e-2)" ZNF587B ENSG00000269343 "Zinc finger protein 587B" E7ETH6 19 57819721-57846238 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Late primary spermatocytes: 1.5;Medullary thymic epithelial cells: 4.8;Sertoli cells: 1.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells" "HPA043800, HPA053762, HPA072145" Uncertain Uncertain Nucleoplasm NA NA "Cluster 41: Basophils - Unknown function" "Cluster 49: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 3 Nucleoplasm "HPA043800: , HPA053762: , HPA072145: " "unprognostic (1.90e-1)" "unprognostic (5.29e-2)" "unprognostic (6.87e-3)" "unprognostic (3.77e-1)" "unprognostic (4.15e-1)" "unprognostic (1.08e-1)" "unprognostic (7.03e-2)" "unprognostic (2.28e-2)" "unprognostic (6.22e-2)" "potential prognostic favorable (7.46e-5)" "unprognostic (7.85e-3)" "unprognostic (1.57e-1)" "unprognostic (3.83e-3)" "unprognostic (4.62e-2)" "unprognostic (6.85e-3)" "unprognostic (5.58e-2)" "unprognostic (1.87e-1)" "unprognostic (1.69e-1)" "unprognostic (1.26e-1)" "unprognostic (3.95e-2)" "unprognostic (9.38e-3)" "potential prognostic unfavorable (6.50e-4)" "unprognostic (7.59e-3)" "unprognostic (4.99e-2)" "potential prognostic unfavorable (1.12e-6)" "unprognostic (8.34e-2)" "unprognostic (1.87e-1)" "unprognostic (1.42e-1)" "unprognostic (4.34e-2)" ZNF589 SZF1 ENSG00000164048 "Zinc finger protein 589" Q86UQ0 3 48241100-48299253 "Predicted intracellular proteins, Transcription factors" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "pDCs: 60.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 36.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Skeletal muscle - Fibroblasts, Spleen - B-cells (Spleen), Testis - Sertoli cells" HPA003145 Uncertain Supported Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 49: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 35: Neurons - Synaptic function & neurogenesis" 4 Nucleoplasm "HPA003145: " "unprognostic (8.33e-3)" "unprognostic (1.86e-1)" "unprognostic (6.62e-3)" "unprognostic (3.81e-3)" "unprognostic (9.70e-2)" "unprognostic (1.80e-1)" "unprognostic (1.69e-1)" "potential prognostic favorable (9.44e-4)" "potential prognostic favorable (7.04e-4)" "potential prognostic unfavorable (1.19e-4)" "potential prognostic favorable (6.58e-4)" "unprognostic (6.27e-2)" "potential prognostic favorable (8.11e-4)" "potential prognostic unfavorable (3.34e-5)" "unprognostic (3.90e-1)" "potential prognostic favorable (9.65e-4)" "unprognostic (5.75e-2)" "unprognostic (4.81e-3)" "potential prognostic favorable (6.02e-4)" "unprognostic (6.16e-2)" "unprognostic (3.41e-1)" "potential prognostic favorable (9.02e-5)" "unprognostic (4.79e-2)" "unprognostic (2.18e-1)" "unprognostic (4.81e-3)" "unprognostic (6.30e-2)" "unprognostic (1.07e-1)" "unprognostic (1.26e-1)" "unprognostic (1.15e-1)" "unprognostic (1.08e-2)" "unprognostic (8.23e-2)" ZNF592 "CAMOS, KIAA0211, SCAR5" ENSG00000166716 "Zinc finger protein 592" Q92610 15 84748592-84806445 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 157.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020332, HPA021600" Approved Approved Nucleoplasm NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 30: White matter - Myelination" "Cluster 58: Non-specific - Nuclear processes" "Cluster 24: Neutrophils - Innate immunity signal integration" 11 Nucleoplasm "HPA020332: , HPA021600: " "unprognostic (2.94e-3)" "unprognostic (1.38e-1)" "unprognostic (7.90e-2)" "unprognostic (1.16e-1)" "unprognostic (9.60e-3)" "unprognostic (1.16e-1)" "unprognostic (3.13e-2)" "unprognostic (3.75e-1)" "unprognostic (8.49e-2)" "unprognostic (5.24e-2)" "validated prognostic favorable (1.97e-4)" "validated prognostic favorable (4.00e-5)" "unprognostic (9.61e-2)" "unprognostic (5.93e-2)" "unprognostic (3.75e-1)" "unprognostic (3.76e-1)" "unprognostic (2.42e-1)" "unprognostic (1.10e-1)" "unprognostic (4.43e-2)" "unprognostic (2.52e-1)" "unprognostic (1.60e-1)" "unprognostic (3.43e-2)" "unprognostic (6.59e-2)" "unprognostic (1.68e-1)" "unprognostic (4.53e-2)" "unprognostic (6.73e-2)" "unprognostic (8.94e-2)" "unprognostic (1.45e-1)" "unprognostic (1.25e-1)" "unprognostic (1.46e-1)" "unprognostic (1.66e-1)" ZNF593 ZT86 ENSG00000142684 "Zinc finger protein 593" O00488 1 26169908-26170873 "Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 225.8;Gastric progenitor cells: 251.2;Hepatocytes: 234.9;Oocytes: 552.6;Syncytiotrophoblasts: 282.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054363, HPA059387" Supported Enhanced Nucleoplasm,Nucleoli NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 24: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 8 Nucleoli Nucleoplasm "HPA054363: , HPA059387: " "unprognostic (2.23e-2)" "unprognostic (2.83e-2)" "unprognostic (1.59e-1)" "unprognostic (1.14e-1)" "unprognostic (9.95e-2)" "unprognostic (3.02e-3)" "unprognostic (1.14e-1)" "unprognostic (1.26e-1)" "unprognostic (1.15e-2)" "unprognostic (2.29e-2)" "unprognostic (3.90e-2)" "unprognostic (1.18e-2)" "unprognostic (1.64e-1)" "potential prognostic unfavorable (7.71e-4)" "unprognostic (1.41e-2)" "unprognostic (1.75e-1)" "potential prognostic unfavorable (1.67e-4)" "unprognostic (2.99e-1)" "unprognostic (2.00e-1)" "unprognostic (3.24e-1)" "unprognostic (1.27e-1)" "unprognostic (2.31e-1)" "unprognostic (1.60e-1)" "unprognostic (9.54e-2)" "unprognostic (4.74e-2)" "unprognostic (5.26e-3)" "unprognostic (1.72e-1)" "unprognostic (2.27e-2)" "unprognostic (1.79e-1)" "unprognostic (6.35e-2)" "unprognostic (4.16e-2)" ZNF593OS ENSG00000236782 "ZNF593 opposite strand" A0A0U1RRA0 1 26169516-26171832 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 6 "retina: 20.0" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 40.7;Epicardial cells: 91.0;Müller glia: 163.2;Ocular epithelial cells: 121.3;Oocytes: 36.8;Retinal amacrine cells: 126.4;Retinal bipolar cells: 88.4;Retinal horizontal cells: 228.4" "Cell type enhanced" "Detected in single" "Bergmann glia: 1.2" "Group enriched" "Detected in some" 7 "Prostate Adenocarcinoma (TCGA): 10.7;Uterine Corpus Endometrial Carcinoma (TCGA): 13.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in single" "cerebellum: 1.2" "Not detected" "Not detected" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 15: Non-specific - Transcription" "Cluster 11: Neuronal - Sensory perception" "Cluster 100: Stratified epithelial cells - Barrier functions" "unprognostic (2.13e-1)" "unprognostic (1.13e-1)" "unprognostic (8.56e-2)" "unprognostic (6.36e-2)" "unprognostic (3.66e-2)" ZNF594 KIAA1871 ENSG00000180626 "Zinc finger protein 594" Q96JF6 17 5179535-5191868 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 41.3;Choroid plexus epithelial cells: 41.3;Myonuclei: 45.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060283, HPA067178, HPA069360, HPA074493, HPA077596" Approved Enhanced Nucleoplasm NA NA "Cluster 34: B-cells - Unknown function" "Cluster 65: Brain - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 42: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" Nucleoplasm "HPA060283: , HPA067178: , HPA069360: , HPA074493: , HPA077596: " "unprognostic (8.75e-2)" "unprognostic (3.75e-2)" "unprognostic (2.02e-1)" "unprognostic (9.55e-3)" "unprognostic (1.62e-3)" "unprognostic (1.31e-1)" "unprognostic (1.87e-1)" "unprognostic (1.71e-1)" "unprognostic (7.59e-3)" "unprognostic (7.39e-2)" "unprognostic (3.79e-3)" "unprognostic (3.46e-3)" "unprognostic (5.51e-2)" "unprognostic (8.47e-2)" "unprognostic (3.84e-1)" "unprognostic (1.66e-1)" "unprognostic (4.73e-2)" "unprognostic (3.37e-3)" "unprognostic (2.15e-1)" "unprognostic (2.48e-1)" "potential prognostic favorable (4.26e-4)" "potential prognostic unfavorable (3.55e-4)" "unprognostic (1.38e-2)" "unprognostic (7.38e-3)" "unprognostic (1.89e-1)" "unprognostic (7.14e-2)" "unprognostic (2.84e-1)" "unprognostic (2.82e-1)" "unprognostic (7.93e-2)" "unprognostic (8.27e-2)" ZNF595 FLJ31740 ENSG00000272602 "Zinc finger protein 595" Q8IYB9 4 53286-88208 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "placenta: 56.9" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Neuroblastoma: 132.6" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 37: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 2 "unprognostic (1.42e-2)" "unprognostic (6.86e-2)" "unprognostic (9.41e-3)" "unprognostic (2.27e-2)" "unprognostic (1.23e-1)" "potential prognostic favorable (3.90e-4)" "unprognostic (8.19e-2)" "unprognostic (9.61e-2)" "unprognostic (1.20e-2)" "validated prognostic favorable (2.20e-4)" "validated prognostic favorable (1.12e-5)" "unprognostic (1.87e-1)" "unprognostic (4.06e-3)" "unprognostic (1.06e-2)" "unprognostic (1.06e-1)" "unprognostic (1.37e-1)" "unprognostic (7.96e-2)" "unprognostic (1.34e-3)" "unprognostic (6.01e-2)" "unprognostic (1.22e-1)" "unprognostic (3.84e-2)" "unprognostic (7.15e-2)" "unprognostic (2.31e-1)" "unprognostic (2.31e-2)" "unprognostic (3.15e-2)" "unprognostic (1.33e-1)" "unprognostic (1.83e-1)" "unprognostic (1.55e-1)" ZNF596 ENSG00000172748 "Zinc finger protein 596" Q8TC21 8 232137-264703 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 81.4;Early spermatids: 47.1;Epicardial cells: 200.1;Late primary spermatocytes: 130.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" HPA055463 Uncertain Approved Nucleoli,Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 15: Non-specific - Transcription" "Cluster 56: Non-specific - Sensory perception" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 1 "Nucleoli, Mitochondria" "HPA055463: " "unprognostic (2.16e-3)" "unprognostic (2.72e-1)" "unprognostic (6.39e-2)" "unprognostic (1.52e-2)" "unprognostic (8.51e-2)" "unprognostic (1.48e-3)" "unprognostic (1.37e-1)" "unprognostic (3.22e-2)" "unprognostic (2.91e-3)" "unprognostic (1.87e-1)" "unprognostic (7.81e-3)" "potential prognostic favorable (8.41e-4)" "unprognostic (2.19e-1)" "unprognostic (1.19e-3)" "unprognostic (3.62e-3)" "potential prognostic favorable (8.01e-4)" "unprognostic (1.13e-1)" "unprognostic (1.33e-1)" "unprognostic (1.32e-1)" "unprognostic (1.50e-1)" "unprognostic (6.11e-2)" "unprognostic (1.45e-2)" "unprognostic (1.71e-2)" "unprognostic (4.31e-2)" "unprognostic (2.95e-2)" "unprognostic (5.31e-3)" "unprognostic (7.02e-2)" "unprognostic (1.12e-1)" "unprognostic (3.34e-2)" "unprognostic (1.07e-1)" "unprognostic (3.13e-2)" ZNF597 "FLJ33071, HIT-4" ENSG00000167981 "Zinc finger protein 597" Q96LX8 16 3432414-3443504 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 12.8;Late primary spermatocytes: 12.4;Tuft cells: 11.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 8.8" "Lineage enriched" "Detected in many" 5 "granulocytes: 8.8" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells" "Low region specificity" "Detected in all" HPA001556 Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 54: Non-specific - Transcription" "Cluster 20: Non-specific - Transcription regulation" 19 "Nucleoplasm, Nucleoli" "HPA001556: " "unprognostic (2.39e-1)" "unprognostic (9.24e-2)" "unprognostic (2.10e-2)" "unprognostic (5.75e-2)" "unprognostic (7.29e-2)" "unprognostic (8.50e-2)" "unprognostic (4.15e-1)" "unprognostic (3.87e-1)" "unprognostic (5.49e-2)" "potential prognostic favorable (8.04e-5)" "unprognostic (5.90e-3)" "unprognostic (6.86e-2)" "unprognostic (5.33e-2)" "unprognostic (1.19e-1)" "unprognostic (3.62e-1)" "unprognostic (4.66e-1)" "unprognostic (2.36e-2)" "unprognostic (3.49e-2)" "unprognostic (2.69e-2)" "unprognostic (4.16e-2)" "unprognostic (3.07e-1)" "unprognostic (1.43e-2)" "unprognostic (3.79e-3)" "potential prognostic favorable (8.66e-4)" "unprognostic (2.95e-1)" "unprognostic (3.08e-2)" "unprognostic (1.77e-1)" "unprognostic (4.56e-2)" "unprognostic (1.92e-2)" ZNF598 "FLJ00086, HEL2" ENSG00000167962 "Zinc finger protein 598, E3 ubiquitin ligase" 16 1997654-2009821 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041760, HPA041896" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 70: Intestinal goblet cells - Mucin production" 39 "Plasma membrane, Cytosol" "HPA041760: , HPA041896: " "unprognostic (2.02e-1)" "unprognostic (6.21e-2)" "unprognostic (2.71e-1)" "unprognostic (3.87e-2)" "unprognostic (1.09e-1)" "unprognostic (1.28e-1)" "unprognostic (2.90e-1)" "unprognostic (4.08e-2)" "unprognostic (6.21e-2)" "unprognostic (6.11e-2)" "unprognostic (1.93e-1)" "unprognostic (1.27e-2)" "unprognostic (3.54e-1)" "unprognostic (7.36e-3)" "unprognostic (1.01e-1)" "potential prognostic unfavorable (7.28e-4)" "unprognostic (5.09e-2)" "unprognostic (6.27e-2)" "unprognostic (1.07e-1)" "unprognostic (9.25e-2)" "unprognostic (1.23e-2)" "unprognostic (1.02e-1)" "unprognostic (8.38e-2)" "unprognostic (3.70e-2)" "unprognostic (8.89e-3)" "unprognostic (1.36e-2)" "unprognostic (4.32e-1)" "unprognostic (1.97e-1)" "unprognostic (1.06e-1)" "unprognostic (1.32e-2)" "unprognostic (1.49e-1)" ZNF599 FLJ30663 ENSG00000153896 "Zinc finger protein 599" Q96NL3 19 34758073-34773229 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 83.9;Epididymal efferent duct ciliated cells: 33.6;Epididymal principal cells: 33.5;Fallopian tube ciliated cells: 32.8;Late primary spermatocytes: 59.7;Late spermatids: 45.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" HPA014701 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 21: Testis - Mixed function" "Cluster 54: Immune cells - T cell receptor" "Cluster 4: Non-specific - Transcription" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 7 "Plasma membrane, Cytosol" Nucleoplasm "HPA014701: " "potential prognostic favorable (2.43e-5)" "unprognostic (1.11e-1)" "unprognostic (1.23e-1)" "unprognostic (8.85e-2)" "unprognostic (1.56e-1)" "potential prognostic favorable (3.87e-5)" "unprognostic (2.75e-1)" "unprognostic (9.15e-2)" "potential prognostic favorable (4.86e-4)" "unprognostic (7.86e-3)" "unprognostic (3.22e-3)" "unprognostic (2.30e-2)" "potential prognostic favorable (2.22e-4)" "unprognostic (9.10e-3)" "unprognostic (7.03e-2)" "unprognostic (2.69e-1)" "unprognostic (3.23e-2)" "potential prognostic favorable (5.67e-4)" "unprognostic (5.45e-3)" "unprognostic (1.57e-1)" "unprognostic (5.07e-3)" "unprognostic (1.89e-1)" "unprognostic (3.51e-2)" "unprognostic (1.22e-1)" "unprognostic (2.12e-2)" "potential prognostic unfavorable (9.01e-4)" "unprognostic (1.26e-1)" "unprognostic (1.31e-1)" "unprognostic (1.40e-1)" "unprognostic (3.93e-2)" ZNF600 "DKFZp686F06123, KR-ZNF1" ENSG00000189190 "Zinc finger protein 600" Q6ZNG1 19 52749942-52786807 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "NK-cells: 59.2" "Cell type enhanced" "Detected in many" "leukocyte: 54.6;upper rhombic lip: 40.6" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 23.6" "Region enriched" "Detected in all" 5 "cerebellum: 20.3" "Immune cell enhanced" "Detected in many" "NK-cell: 52.5" "Group enriched" "Detected in all" 5 "NK-cells: 52.5;T-cells: 21.6" "Low cancer specificity" "Detected in all" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 35: Non-specific - DNA binding" "Cluster 4: Non-specific - Transcription" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 4 "potential prognostic favorable (4.86e-5)" "unprognostic (2.09e-2)" "unprognostic (1.13e-1)" "unprognostic (1.42e-2)" "unprognostic (5.60e-2)" "unprognostic (1.48e-2)" "unprognostic (5.25e-2)" "unprognostic (1.48e-2)" "unprognostic (1.28e-1)" "unprognostic (6.33e-3)" "unprognostic (2.14e-2)" "unprognostic (2.54e-1)" "unprognostic (1.89e-1)" "potential prognostic unfavorable (1.86e-5)" "unprognostic (1.20e-1)" "unprognostic (1.47e-1)" "unprognostic (8.97e-2)" "unprognostic (3.17e-2)" "unprognostic (2.32e-1)" "unprognostic (2.96e-1)" "unprognostic (1.02e-1)" "unprognostic (6.08e-2)" "unprognostic (2.47e-1)" "unprognostic (3.05e-2)" "unprognostic (8.71e-3)" "unprognostic (7.22e-2)" "unprognostic (2.96e-3)" "unprognostic (1.67e-2)" "unprognostic (9.80e-2)" "potential prognostic unfavorable (4.14e-4)" "unprognostic (3.39e-1)" ZNF605 ENSG00000196458 "Zinc finger protein 605" Q86T29 12 132918306-132956306 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Tuft cells: 11.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA061970, HPA062655" Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 69: Parathyroid gland - Mixed function" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 4: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 1 Nucleoplasm Vesicles "HPA061970: , HPA062655: " "unprognostic (1.11e-1)" "unprognostic (4.17e-2)" "unprognostic (1.72e-2)" "unprognostic (2.70e-2)" "unprognostic (1.57e-1)" "unprognostic (5.32e-2)" "unprognostic (4.66e-2)" "unprognostic (1.27e-2)" "unprognostic (6.18e-2)" "unprognostic (1.79e-1)" "unprognostic (3.82e-1)" "unprognostic (8.51e-3)" "unprognostic (1.67e-1)" "potential prognostic unfavorable (1.65e-6)" "unprognostic (6.91e-2)" "unprognostic (5.06e-2)" "unprognostic (9.52e-2)" "unprognostic (3.01e-1)" "unprognostic (1.17e-1)" "unprognostic (2.43e-1)" "unprognostic (3.23e-2)" "unprognostic (8.20e-2)" "unprognostic (1.03e-2)" "unprognostic (5.80e-2)" "unprognostic (1.20e-1)" "unprognostic (2.00e-1)" "unprognostic (1.98e-1)" "unprognostic (9.46e-2)" "unprognostic (2.69e-1)" "unprognostic (2.10e-2)" "unprognostic (2.08e-1)" ZNF606 "FLJ14260, KIAA1852, ZNF328" ENSG00000166704 "Zinc finger protein 606" Q8WXB4 19 57977076-58003349 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 8 "Cardiomyocytes: 397.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041712, HPA043584" Uncertain Supported Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 49: Non-specific - Transcription" "Cluster 46: Brainstem - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 1 Nucleoplasm "HPA041712: , HPA043584: " "potential prognostic favorable (6.30e-4)" "unprognostic (1.09e-1)" "unprognostic (1.65e-1)" "unprognostic (1.61e-1)" "unprognostic (6.00e-2)" "unprognostic (1.53e-3)" "unprognostic (8.68e-2)" "unprognostic (2.63e-1)" "unprognostic (9.80e-3)" "unprognostic (7.63e-2)" "unprognostic (2.78e-1)" "unprognostic (2.51e-3)" "unprognostic (3.61e-2)" "unprognostic (5.13e-2)" "unprognostic (7.01e-2)" "unprognostic (8.91e-2)" "unprognostic (7.78e-2)" "unprognostic (9.99e-2)" "unprognostic (2.44e-3)" "unprognostic (2.45e-1)" "unprognostic (4.39e-1)" "unprognostic (8.99e-3)" "unprognostic (2.37e-3)" "unprognostic (5.75e-2)" "unprognostic (4.52e-2)" "unprognostic (1.32e-1)" "unprognostic (1.54e-2)" "unprognostic (1.81e-2)" "unprognostic (1.74e-1)" "unprognostic (1.14e-2)" "unprognostic (6.75e-2)" ZNF607 "FLJ14802, MGC13071" ENSG00000198182 "Zinc finger protein 607" Q96SK3 19 37696371-37719761 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Early spermatids: 10.3;Late spermatids: 13.1;Tuft cells: 11.5" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "HPA049465, HPA055018" Uncertain Approved Nucleoplasm NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 21: Testis - Mixed function" "Cluster 30: White matter - Myelination" "Cluster 4: Non-specific - Transcription" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 7 Nucleoplasm "HPA049465: , HPA055018: " "potential prognostic favorable (3.60e-4)" "unprognostic (6.50e-2)" "unprognostic (1.10e-1)" "unprognostic (2.63e-2)" "unprognostic (4.50e-3)" "unprognostic (1.64e-2)" "unprognostic (3.02e-1)" "unprognostic (3.49e-1)" "unprognostic (5.38e-2)" "unprognostic (2.40e-1)" "validated prognostic favorable (2.58e-4)" "validated prognostic favorable (2.25e-4)" "unprognostic (4.39e-2)" "unprognostic (1.41e-1)" "unprognostic (3.32e-1)" "unprognostic (1.78e-1)" "unprognostic (1.34e-1)" "unprognostic (1.29e-1)" "unprognostic (8.60e-2)" "unprognostic (2.46e-1)" "potential prognostic favorable (7.49e-4)" "unprognostic (2.00e-1)" "unprognostic (5.50e-2)" "potential prognostic favorable (2.08e-5)" "unprognostic (3.50e-1)" "unprognostic (1.05e-2)" "unprognostic (1.57e-1)" "unprognostic (4.43e-2)" "unprognostic (1.11e-1)" "unprognostic (1.26e-1)" ZNF608 "DKFZp434M098, KIAA1281, NY-REN-36" ENSG00000168916 "Zinc finger protein 608" Q9ULD9 5 124636913-124748807 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 475.8;Oligodendrocyte progenitor cells: 298.4;Oligodendrocytes: 295.1;Pituitary stem cells: 363.7;Tuft cells: 357.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.5;naive B-cell: 1.5" "Group enriched" "Detected in many" 4 "B-cells: 1.5;granulocytes: 2.5" "Low cancer specificity" "Detected in many" "Pituitary gland - Undifferentiated cells (Pituitary gland), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005545, HPA076984" Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 32: Basophils - Transcription" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 11: White matter - Signal transduction" "Cluster 6: Leukemia - Signal transduction" "Cluster 24: Neutrophils - Innate immunity signal integration" 8 Nucleoplasm Mitochondria "HPA005545: , HPA076984: " "unprognostic (1.70e-3)" "unprognostic (1.82e-1)" "unprognostic (7.99e-2)" "unprognostic (1.66e-1)" "unprognostic (6.98e-2)" "unprognostic (2.20e-1)" "unprognostic (5.26e-1)" "unprognostic (1.08e-1)" "unprognostic (1.23e-1)" "unprognostic (8.86e-2)" "unprognostic (2.28e-2)" "unprognostic (1.55e-1)" "unprognostic (4.76e-2)" "unprognostic (1.68e-1)" "unprognostic (3.58e-2)" "unprognostic (1.21e-1)" "unprognostic (1.23e-1)" "unprognostic (4.10e-2)" "unprognostic (6.86e-2)" "unprognostic (6.06e-3)" "unprognostic (1.33e-2)" "unprognostic (2.35e-1)" "unprognostic (4.41e-2)" "unprognostic (4.44e-2)" "unprognostic (5.67e-2)" "unprognostic (1.22e-1)" "unprognostic (1.86e-1)" "unprognostic (2.61e-2)" "unprognostic (1.55e-1)" "unprognostic (5.90e-2)" "unprognostic (6.92e-2)" ZNF609 KIAA0295 ENSG00000180357 "Zinc finger protein 609" O15014 15 64460578-64686068 "Predicted intracellular proteins" "Myogenesis, Transcription, Transcription regulation" "Activator, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040742, HPA040832" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 39: Testis - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 22 Nucleoplasm Cytosol "HPA040742: , HPA040832: " "unprognostic (2.97e-2)" "unprognostic (1.14e-1)" "unprognostic (4.56e-1)" "unprognostic (4.05e-3)" "unprognostic (1.69e-1)" "unprognostic (3.19e-3)" "unprognostic (1.24e-1)" "unprognostic (2.97e-3)" "unprognostic (1.52e-1)" "unprognostic (2.33e-2)" "unprognostic (1.80e-3)" "unprognostic (2.16e-3)" "unprognostic (2.43e-1)" "unprognostic (7.44e-2)" "unprognostic (1.46e-1)" "unprognostic (1.57e-1)" "unprognostic (3.82e-3)" "unprognostic (2.35e-1)" "unprognostic (3.55e-1)" "unprognostic (1.44e-2)" "unprognostic (6.11e-2)" "unprognostic (9.64e-2)" "unprognostic (1.80e-2)" "unprognostic (9.65e-2)" "unprognostic (4.26e-2)" "unprognostic (1.08e-2)" "unprognostic (1.30e-1)" "unprognostic (1.09e-1)" "unprognostic (3.28e-1)" "unprognostic (1.59e-2)" "unprognostic (4.38e-2)" ZNF610 FLJ36040 ENSG00000167554 "Zinc finger protein 610" Q8N9Z0 19 52336243-52367778 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 44.0;Late primary spermatocytes: 26.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 15.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Testis - Early spermatids" "HPA055771, HPA078134" Enhanced Approved Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 65: Brain - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 94: Gonadal somatic cells - Mixed function" Nucleoplasm "HPA055771: , HPA078134: " "unprognostic (9.15e-2)" "unprognostic (1.43e-1)" "unprognostic (1.22e-1)" "unprognostic (2.81e-1)" "unprognostic (7.36e-2)" "unprognostic (1.33e-1)" "unprognostic (1.29e-1)" "validated prognostic favorable (4.32e-5)" "validated prognostic favorable (1.93e-5)" "unprognostic (1.07e-1)" "unprognostic (6.56e-2)" "unprognostic (2.56e-1)" "unprognostic (7.60e-3)" "unprognostic (5.03e-2)" "unprognostic (2.20e-3)" "unprognostic (3.22e-1)" "unprognostic (1.89e-1)" "unprognostic (1.64e-1)" "unprognostic (1.27e-1)" "unprognostic (2.24e-1)" "unprognostic (2.79e-1)" "unprognostic (2.55e-2)" "unprognostic (8.71e-2)" "unprognostic (6.31e-2)" "unprognostic (6.06e-2)" "unprognostic (8.55e-2)" ZNF611 MGC5384 ENSG00000213020 "Zinc finger protein 611" Q8N823 19 52702813-52735073 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 150.0;Ocular epithelial cells: 180.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 100: Stratified epithelial cells - Barrier functions" 1 "unprognostic (7.70e-2)" "unprognostic (1.60e-3)" "unprognostic (1.39e-1)" "unprognostic (1.43e-1)" "unprognostic (1.14e-1)" "unprognostic (4.81e-2)" "unprognostic (2.36e-1)" "unprognostic (1.11e-1)" "unprognostic (1.34e-1)" "unprognostic (3.33e-2)" "validated prognostic favorable (4.56e-8)" "validated prognostic favorable (5.28e-4)" "unprognostic (9.04e-2)" "unprognostic (1.01e-1)" "unprognostic (2.38e-1)" "unprognostic (4.11e-1)" "unprognostic (9.42e-2)" "unprognostic (2.71e-1)" "unprognostic (1.12e-1)" "unprognostic (9.65e-2)" "unprognostic (3.29e-2)" "unprognostic (4.86e-2)" "unprognostic (1.53e-1)" "unprognostic (1.01e-1)" "unprognostic (4.52e-3)" "unprognostic (1.23e-2)" "unprognostic (1.49e-1)" "unprognostic (2.58e-1)" "unprognostic (2.30e-2)" "unprognostic (2.95e-1)" ZNF613 FLJ13590 ENSG00000176024 "Zinc finger protein 613" Q6PF04 19 51927147-51948759 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "prostate: 18.2" "Cell type enhanced" "Detected in many" "Prostatic glandular cells: 26.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 27.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "prostate cancer: 24.6" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" HPA026833 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 60: Prostate cancer - Unknown function" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 4 Nucleoplasm Vesicles "HPA026833: " "unprognostic (1.49e-1)" "unprognostic (2.40e-2)" "unprognostic (9.09e-2)" "unprognostic (5.38e-3)" "unprognostic (4.21e-2)" "unprognostic (4.03e-2)" "unprognostic (2.84e-1)" "unprognostic (2.72e-2)" "unprognostic (5.57e-2)" "unprognostic (2.39e-1)" "validated prognostic favorable (9.67e-7)" "validated prognostic favorable (3.38e-5)" "unprognostic (3.82e-3)" "unprognostic (4.00e-2)" "unprognostic (4.85e-2)" "unprognostic (8.55e-2)" "unprognostic (9.92e-2)" "unprognostic (1.29e-2)" "unprognostic (8.27e-2)" "unprognostic (1.96e-2)" "unprognostic (1.65e-1)" "unprognostic (1.23e-1)" "unprognostic (6.48e-2)" "unprognostic (9.18e-2)" "unprognostic (3.19e-2)" "unprognostic (9.52e-3)" "unprognostic (2.55e-3)" "unprognostic (6.53e-2)" "unprognostic (1.05e-1)" "unprognostic (3.49e-2)" "unprognostic (2.04e-1)" ZNF614 FLJ21941 ENSG00000142556 "Zinc finger protein 614" Q8N883 19 52012765-52030240 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 37.5;Early spermatids: 72.7;Late spermatids: 49.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" HPA021197 Uncertain Approved Nucleoplasm,Vesicles,Cytosol No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 40: Non-specific - Mixed function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 3 Nucleoplasm "Vesicles, Cytosol" "HPA021197: " "unprognostic (2.49e-2)" "unprognostic (9.69e-2)" "unprognostic (1.31e-1)" "unprognostic (4.32e-3)" "unprognostic (2.48e-2)" "unprognostic (3.01e-1)" "unprognostic (2.05e-2)" "unprognostic (2.55e-1)" "unprognostic (5.62e-1)" "unprognostic (8.77e-2)" "validated prognostic favorable (7.07e-6)" "validated prognostic favorable (7.38e-4)" "unprognostic (2.17e-1)" "unprognostic (1.87e-2)" "unprognostic (1.59e-1)" "unprognostic (1.95e-1)" "unprognostic (2.90e-1)" "potential prognostic favorable (3.52e-6)" "unprognostic (4.85e-1)" "unprognostic (3.73e-1)" "unprognostic (8.92e-2)" "unprognostic (5.46e-2)" "unprognostic (1.22e-1)" "unprognostic (2.65e-2)" "unprognostic (1.30e-2)" "unprognostic (2.01e-1)" "unprognostic (3.04e-2)" "unprognostic (6.29e-3)" "unprognostic (2.32e-1)" "unprognostic (7.03e-2)" "unprognostic (2.44e-1)" ZNF615 FLJ33710 ENSG00000197619 "Zinc finger protein 615" Q8N8J6 19 51991332-52008230 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Prostatic glandular cells: 28.7" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 20.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052422 Uncertain Approved Nucleoli,Mitochondria NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 60: Prostate cancer - Unknown function" "Cluster 7: Non-specific - Transcription" Mitochondria Nucleoli "HPA052422: " "potential prognostic favorable (2.68e-4)" "unprognostic (1.94e-1)" "unprognostic (1.68e-1)" "potential prognostic unfavorable (1.65e-4)" "unprognostic (1.36e-2)" "unprognostic (9.74e-2)" "unprognostic (2.42e-2)" "unprognostic (2.48e-2)" "unprognostic (1.09e-1)" "unprognostic (3.42e-3)" "validated prognostic favorable (2.77e-6)" "validated prognostic favorable (3.07e-5)" "unprognostic (1.09e-1)" "unprognostic (4.48e-2)" "unprognostic (8.40e-2)" "unprognostic (9.73e-2)" "unprognostic (3.07e-1)" "unprognostic (9.75e-2)" "unprognostic (2.70e-1)" "unprognostic (1.95e-1)" "unprognostic (7.91e-2)" "unprognostic (2.28e-2)" "unprognostic (1.47e-1)" "unprognostic (4.40e-2)" "unprognostic (1.13e-1)" "unprognostic (7.83e-2)" "unprognostic (7.04e-2)" "unprognostic (3.59e-2)" "unprognostic (2.15e-1)" "unprognostic (2.85e-2)" "unprognostic (3.70e-1)" ZNF616 MGC45556 ENSG00000204611 "Zinc finger protein 616" Q08AN1 19 52113091-52139938 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "HPA062639, HPA071539" Approved Approved Centrosome NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 4: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 1 Centrosome "HPA062639: , HPA071539: " "unprognostic (3.14e-2)" "unprognostic (4.95e-3)" "unprognostic (8.48e-2)" "unprognostic (9.50e-2)" "unprognostic (1.06e-1)" "unprognostic (4.91e-3)" "unprognostic (2.37e-1)" "unprognostic (1.88e-1)" "unprognostic (1.76e-1)" "unprognostic (1.89e-2)" "unprognostic (3.19e-2)" "potential prognostic favorable (2.18e-4)" "unprognostic (3.04e-1)" "unprognostic (2.77e-3)" "unprognostic (3.31e-2)" "unprognostic (2.80e-1)" "unprognostic (3.51e-1)" "unprognostic (1.02e-1)" "unprognostic (6.15e-2)" "unprognostic (2.04e-1)" "unprognostic (3.52e-3)" "unprognostic (1.88e-1)" "unprognostic (2.23e-2)" "unprognostic (4.94e-2)" "unprognostic (2.06e-2)" "unprognostic (7.72e-2)" "unprognostic (4.89e-2)" "unprognostic (1.36e-2)" "unprognostic (4.28e-2)" "unprognostic (2.74e-2)" "unprognostic (8.66e-2)" ZNF618 "KIAA1952, NEDD10" ENSG00000157657 "Zinc finger protein 618" Q5T7W0 9 113876282-114056593 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 160.7;Distal convoluted tubule cells: 183.9;Loop of henle epithelial cells: 176.8;Renal collecting duct intercalated cells: 176.4;Renal connecting tubule cells: 223.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA023116, HPA061732" Uncertain Approved Nucleoplasm NA NA "Cluster 41: Basophils - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 13 Nucleoplasm "HPA023116: , HPA061732: " "unprognostic (1.99e-1)" "unprognostic (3.92e-1)" "unprognostic (6.10e-2)" "unprognostic (7.80e-2)" "unprognostic (1.06e-1)" "unprognostic (7.22e-3)" "unprognostic (2.01e-3)" "unprognostic (1.20e-1)" "unprognostic (2.46e-1)" "unprognostic (2.96e-2)" "validated prognostic favorable (1.96e-5)" "validated prognostic favorable (3.78e-4)" "unprognostic (2.49e-2)" "unprognostic (1.80e-1)" "unprognostic (1.25e-2)" "unprognostic (6.43e-2)" "unprognostic (8.07e-2)" "unprognostic (9.38e-2)" "unprognostic (8.88e-2)" "unprognostic (5.44e-2)" "unprognostic (3.97e-2)" "unprognostic (1.57e-2)" "unprognostic (2.76e-1)" "unprognostic (1.98e-1)" "unprognostic (2.52e-1)" "unprognostic (3.23e-1)" "unprognostic (3.70e-2)" "unprognostic (3.62e-2)" "unprognostic (2.03e-1)" "unprognostic (3.77e-2)" "unprognostic (1.41e-1)" ZNF619 FLJ90764 ENSG00000177873 "Zinc finger protein 619" Q8N2I2 3 40477113-40491053 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 1.7;Distal convoluted tubule cells: 3.0;Erythrocytes: 1.5;Loop of henle epithelial cells: 3.2;Megakaryocyte-Erythroid progenitors: 1.5;Papillary tip epithelial cells: 1.8;Proximal tubule cells: 2.1;Renal collecting duct intercalated cells: 2.6;Renal collecting duct principal cells: 2.3;Renal connecting tubule cells: 2.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" HPA045094 Uncertain Approved "Nucleoplasm,Intermediate filaments" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 42: Retina - Visual perception" "Cluster 11: White matter - Signal transduction" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 105: Non-specific - Mixed function" 1 Nucleoplasm "Intermediate filaments" "HPA045094: " "unprognostic (1.61e-1)" "unprognostic (1.58e-1)" "unprognostic (1.33e-1)" "unprognostic (3.09e-2)" "unprognostic (1.91e-1)" "unprognostic (4.23e-2)" "unprognostic (9.10e-2)" "unprognostic (2.63e-1)" "unprognostic (3.79e-3)" "unprognostic (1.86e-3)" "unprognostic (1.34e-3)" "unprognostic (2.02e-2)" "unprognostic (2.95e-2)" "unprognostic (2.36e-2)" "unprognostic (1.33e-1)" "unprognostic (5.10e-2)" "unprognostic (1.97e-1)" "unprognostic (1.72e-1)" "unprognostic (1.57e-2)" "unprognostic (1.93e-1)" "unprognostic (3.90e-2)" "unprognostic (1.01e-1)" "unprognostic (4.18e-1)" "unprognostic (5.52e-2)" "unprognostic (5.13e-2)" "unprognostic (2.59e-2)" "unprognostic (5.98e-3)" "unprognostic (2.89e-1)" "unprognostic (1.93e-1)" "unprognostic (3.26e-1)" "unprognostic (6.11e-2)" ZNF620 MGC50836 ENSG00000177842 "Zinc finger protein 620" Q6ZNG0 3 40477131-40518736 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 32.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 7.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "HPA031452, HPA059383" Uncertain Approved Centrosome NA NA "Cluster 41: Basophils - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 25: Non-specific - Transcription" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 56 Centrosome "HPA031452: , HPA059383: " "unprognostic (4.26e-2)" "unprognostic (3.34e-2)" "unprognostic (6.43e-3)" "unprognostic (1.39e-2)" "unprognostic (1.62e-1)" "unprognostic (6.00e-2)" "unprognostic (2.27e-1)" "unprognostic (1.51e-2)" "unprognostic (5.00e-2)" "validated prognostic favorable (2.38e-4)" "validated prognostic favorable (8.75e-4)" "unprognostic (1.01e-3)" "potential prognostic unfavorable (5.02e-4)" "unprognostic (2.64e-2)" "unprognostic (3.40e-1)" "unprognostic (1.90e-1)" "unprognostic (1.55e-1)" "unprognostic (1.07e-2)" "unprognostic (1.30e-1)" "unprognostic (1.81e-2)" "unprognostic (1.26e-2)" "unprognostic (2.64e-1)" "unprognostic (8.98e-2)" "unprognostic (1.92e-3)" "unprognostic (3.25e-1)" "unprognostic (1.80e-1)" "unprognostic (1.46e-1)" "unprognostic (2.43e-1)" "unprognostic (5.29e-2)" "unprognostic (1.94e-1)" ZNF621 FLJ45246 ENSG00000172888 "Zinc finger protein 621" Q6ZSS3 3 40524878-40574685 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065518, HPA071440" Enhanced "Nuclear speckles" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Transcription" 2 "Nuclear speckles" "HPA065518: , HPA071440: " "unprognostic (7.60e-2)" "unprognostic (1.46e-1)" "unprognostic (6.59e-2)" "unprognostic (5.83e-2)" "unprognostic (4.87e-3)" "unprognostic (1.34e-1)" "unprognostic (1.23e-1)" "unprognostic (5.81e-2)" "unprognostic (7.79e-3)" "potential prognostic unfavorable (1.79e-4)" "unprognostic (3.17e-2)" "unprognostic (9.14e-2)" "unprognostic (4.03e-3)" "unprognostic (2.06e-3)" "unprognostic (6.12e-2)" "unprognostic (5.92e-2)" "unprognostic (3.50e-2)" "unprognostic (1.35e-1)" "unprognostic (9.57e-2)" "unprognostic (6.67e-2)" "unprognostic (1.92e-1)" "unprognostic (1.45e-1)" "unprognostic (1.25e-2)" "potential prognostic unfavorable (7.33e-4)" "unprognostic (4.40e-3)" "potential prognostic favorable (9.90e-6)" "unprognostic (7.15e-3)" "unprognostic (2.52e-1)" "unprognostic (2.64e-1)" "unprognostic (4.63e-2)" "unprognostic (3.20e-1)" ZNF622 "MGC17552, MGC2485, ZPR9" ENSG00000173545 "Zinc finger protein 622" Q969S3 5 16451519-16465800 "Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 147.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036514, HPA036515" Uncertain Supported "Nucleoplasm,Nucleoli,Golgi apparatus,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 24: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 29: Non-specific - Unknown function" "Cluster 51: Secretory epithelial cells - Mixed function" 26 Cytosol "Nucleoplasm, Nucleoli, Golgi apparatus" "HPA036514: , HPA036515: " "unprognostic (7.20e-2)" "unprognostic (9.15e-3)" "unprognostic (8.44e-2)" "unprognostic (2.85e-1)" "unprognostic (1.76e-1)" "unprognostic (1.74e-1)" "unprognostic (2.06e-2)" "unprognostic (2.99e-2)" "unprognostic (2.69e-2)" "unprognostic (2.31e-3)" "potential prognostic favorable (6.75e-7)" "unprognostic (7.55e-3)" "unprognostic (3.32e-1)" "potential prognostic unfavorable (3.92e-4)" "unprognostic (1.08e-2)" "unprognostic (1.48e-1)" "potential prognostic unfavorable (9.14e-4)" "unprognostic (2.94e-1)" "unprognostic (3.43e-1)" "unprognostic (3.85e-1)" "unprognostic (3.18e-1)" "unprognostic (1.99e-1)" "unprognostic (8.74e-2)" "unprognostic (8.01e-2)" "unprognostic (8.23e-2)" "unprognostic (3.57e-2)" "unprognostic (1.03e-1)" "unprognostic (3.97e-2)" "unprognostic (2.04e-1)" "unprognostic (1.43e-1)" "unprognostic (2.73e-1)" ZNF623 KIAA0628 ENSG00000183309 "Zinc finger protein 623" O75123 8 143636019-143656418 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 10.4;Bergmann glia: 11.8;Brain excitatory neurons: 20.0;Brain inhibitory neurons: 17.5;Choroid plexus epithelial cells: 18.7;Distal convoluted tubule cells: 13.0;Ependymal cells: 9.5;Loop of henle epithelial cells: 13.1;Microglia: 17.8;Oligodendrocyte progenitor cells: 9.6;Oligodendrocytes: 12.8;Other brain neurons: 15.1;Papillary tip epithelial cells: 11.1;Podocytes: 14.7;Proximal tubule cells: 18.0;Renal collecting duct intercalated cells: 15.1;Renal collecting duct principal cells: 12.6;Renal connecting tubule cells: 11.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044372 Uncertain Approved Nucleoplasm NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 64: Non-specific - Transcription" "Cluster 24: Neurons - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 102: Non-specific - Mixed function" 2 Nucleoplasm "HPA044372: " "unprognostic (1.67e-2)" "unprognostic (8.72e-3)" "unprognostic (3.27e-1)" "unprognostic (4.40e-2)" "unprognostic (1.76e-2)" "unprognostic (7.16e-3)" "unprognostic (2.02e-1)" "unprognostic (4.54e-3)" "unprognostic (8.38e-2)" "unprognostic (1.32e-2)" "unprognostic (1.74e-1)" "potential prognostic favorable (6.40e-5)" "unprognostic (7.90e-2)" "unprognostic (5.21e-2)" "unprognostic (9.59e-2)" "unprognostic (3.11e-1)" "unprognostic (8.50e-3)" "unprognostic (1.31e-1)" "unprognostic (1.52e-3)" "unprognostic (1.11e-1)" "unprognostic (4.03e-2)" "unprognostic (4.81e-3)" "potential prognostic unfavorable (1.27e-4)" "unprognostic (3.42e-1)" "unprognostic (1.69e-1)" "unprognostic (9.83e-2)" "unprognostic (3.27e-2)" "unprognostic (1.70e-1)" "unprognostic (2.18e-1)" "unprognostic (2.93e-1)" "unprognostic (2.35e-1)" ZNF624 KIAA1349 ENSG00000197566 "Zinc finger protein 624" Q9P2J8 17 16620734-16653856 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 23.7;Oligodendrocytes: 21.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "testis cancer: 11.1" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "HPA023157, HPA023244" Uncertain Approved Vesicles NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 8 Vesicles "HPA023157: , HPA023244: " "unprognostic (2.07e-1)" "unprognostic (6.03e-3)" "unprognostic (1.39e-1)" "unprognostic (6.01e-2)" "unprognostic (6.39e-3)" "unprognostic (5.30e-2)" "potential prognostic favorable (2.36e-5)" "unprognostic (1.94e-2)" "unprognostic (2.36e-2)" "unprognostic (1.54e-1)" "unprognostic (1.75e-1)" "unprognostic (3.68e-2)" "unprognostic (1.14e-1)" "potential prognostic unfavorable (1.63e-5)" "unprognostic (1.82e-1)" "unprognostic (1.47e-2)" "unprognostic (1.37e-1)" "unprognostic (3.52e-1)" "unprognostic (4.92e-2)" "unprognostic (3.47e-1)" "unprognostic (4.39e-2)" "unprognostic (1.91e-1)" ZNF625 ENSG00000257591 "Zinc finger protein 625" Q96I27 19 12142090-12156734 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 8.2" "Group enriched" "Detected in some" 6 "Astrocytes: 10.1;Bergmann glia: 14.7;Brain excitatory neurons: 12.6;Brain inhibitory neurons: 10.4;Choroid plexus epithelial cells: 11.7;Ependymal cells: 11.4;Microglia: 8.5;Oligodendrocyte progenitor cells: 14.4;Oligodendrocytes: 8.8;Other brain neurons: 14.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 17.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" HPA074014 Approved Nucleoplasm,Mitochondria NA NA "Cluster 24: Non-specific - Transcription" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 22: Non-specific - Basic cellular functions" 4 Mitochondria Nucleoplasm "HPA074014: " "unprognostic (2.63e-2)" "unprognostic (6.94e-2)" "unprognostic (3.04e-2)" "unprognostic (1.48e-2)" "unprognostic (1.01e-1)" "unprognostic (4.33e-2)" "unprognostic (9.72e-3)" "unprognostic (3.09e-3)" "unprognostic (1.75e-1)" "unprognostic (3.12e-1)" "unprognostic (1.33e-2)" "unprognostic (3.50e-3)" "unprognostic (5.97e-3)" "unprognostic (5.72e-2)" "unprognostic (5.89e-2)" "unprognostic (7.74e-2)" "unprognostic (2.09e-1)" "unprognostic (1.80e-1)" "unprognostic (3.95e-3)" "unprognostic (2.00e-1)" "unprognostic (1.49e-1)" "unprognostic (1.31e-1)" "unprognostic (2.42e-2)" "unprognostic (2.20e-2)" "unprognostic (1.20e-1)" "unprognostic (7.16e-2)" "unprognostic (2.62e-1)" ZNF626 ENSG00000188171 "Zinc finger protein 626" Q68DY1 19 20619939-20661596 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 6.0;Extravillous trophoblasts: 5.6;Retinal pigment epithelial cells: 8.5;Syncytiotrophoblasts: 6.6;Urothelial cells: 6.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" HPA045631 Uncertain Approved "Nucleoplasm,Nuclear membrane,Vesicles" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." "Nuclear membrane, Vesicles" Nucleoplasm "HPA045631: " "unprognostic (7.53e-3)" "unprognostic (1.46e-1)" "unprognostic (5.88e-2)" "unprognostic (1.55e-2)" "unprognostic (2.79e-2)" "unprognostic (1.98e-3)" "unprognostic (2.82e-1)" "unprognostic (7.78e-2)" "unprognostic (2.24e-3)" "potential prognostic favorable (3.48e-6)" "unprognostic (5.30e-2)" "unprognostic (1.45e-1)" "unprognostic (6.15e-3)" "unprognostic (2.02e-1)" "unprognostic (1.93e-1)" "unprognostic (4.84e-2)" "unprognostic (4.49e-2)" "unprognostic (4.08e-2)" "unprognostic (1.35e-2)" "potential prognostic unfavorable (1.68e-4)" "unprognostic (1.39e-1)" "unprognostic (7.43e-2)" "unprognostic (1.59e-1)" "unprognostic (3.77e-2)" "unprognostic (1.41e-1)" "unprognostic (1.45e-2)" "unprognostic (1.08e-2)" "unprognostic (1.44e-1)" "unprognostic (3.97e-1)" "unprognostic (6.87e-3)" ZNF627 FLJ90365 ENSG00000198551 "Zinc finger protein 627" Q7L945 19 11559374-11619161 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Not detected" "Not detected" "HPA049770, HPA073463" Uncertain Approved Nucleoplasm,Nucleoli NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 23: Non-specific - Transcription" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 9 Nucleoplasm Nucleoli "HPA049770: , HPA073463: " "unprognostic (2.61e-3)" "unprognostic (8.97e-2)" "potential prognostic unfavorable (7.30e-4)" "unprognostic (2.39e-1)" "unprognostic (1.30e-1)" "unprognostic (1.99e-1)" "unprognostic (1.12e-2)" "unprognostic (6.30e-2)" "unprognostic (3.76e-3)" "unprognostic (4.62e-2)" "potential prognostic favorable (1.41e-8)" "unprognostic (3.67e-3)" "unprognostic (5.11e-2)" "unprognostic (2.68e-1)" "unprognostic (5.96e-2)" "unprognostic (7.63e-2)" "unprognostic (1.09e-2)" "unprognostic (3.28e-1)" "unprognostic (3.39e-2)" "unprognostic (6.83e-2)" "unprognostic (6.27e-2)" "unprognostic (1.78e-1)" "unprognostic (3.11e-1)" "unprognostic (2.09e-2)" "unprognostic (6.65e-3)" "unprognostic (2.16e-1)" "unprognostic (8.14e-3)" "unprognostic (3.77e-1)" "unprognostic (1.28e-2)" "unprognostic (1.11e-1)" "unprognostic (6.93e-2)" ZNF628 "ZEC, Zfp628" ENSG00000197483 "Zinc finger protein 628" Q5EBL2 19 55476617-55484487 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 21.8" "Cell type enriched" "Detected in many" 5 "Late spermatids: 212.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044451 Uncertain Approved Nucleoplasm NA NA "Cluster 67: Testis - Mixed function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 2 Nucleoplasm "HPA044451: " "unprognostic (3.12e-2)" "unprognostic (4.84e-2)" "unprognostic (1.64e-1)" "potential prognostic unfavorable (6.24e-4)" "unprognostic (1.67e-1)" "unprognostic (1.61e-2)" "unprognostic (6.63e-2)" "unprognostic (4.28e-2)" "unprognostic (5.77e-3)" "potential prognostic favorable (8.30e-4)" "unprognostic (1.40e-1)" "unprognostic (7.37e-2)" "unprognostic (1.65e-3)" "unprognostic (9.02e-2)" "unprognostic (3.43e-2)" "unprognostic (4.94e-2)" "unprognostic (7.81e-3)" "unprognostic (2.31e-1)" "unprognostic (7.66e-3)" "unprognostic (5.16e-2)" "unprognostic (1.92e-1)" "unprognostic (2.90e-1)" "unprognostic (1.14e-2)" "unprognostic (2.46e-1)" "unprognostic (1.06e-1)" "unprognostic (2.02e-1)" "unprognostic (9.37e-3)" "unprognostic (1.68e-1)" ZNF629 "KIAA0326, ZNF65" ENSG00000102870 "Zinc finger protein 629" Q9UEG4 16 30778456-30787205 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019550, HPA056051" Uncertain Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 29 Nucleoplasm "Golgi apparatus" "HPA019550: , HPA056051: " "unprognostic (1.20e-2)" "unprognostic (7.75e-2)" "unprognostic (2.00e-2)" "unprognostic (5.13e-2)" "unprognostic (2.17e-1)" "unprognostic (2.87e-1)" "unprognostic (3.30e-1)" "unprognostic (1.38e-3)" "unprognostic (2.44e-2)" "unprognostic (1.40e-1)" "potential prognostic favorable (5.31e-5)" "unprognostic (2.67e-2)" "unprognostic (1.69e-3)" "unprognostic (2.78e-3)" "unprognostic (1.08e-1)" "unprognostic (8.55e-2)" "unprognostic (2.56e-1)" "unprognostic (3.32e-2)" "unprognostic (3.68e-3)" "unprognostic (1.72e-2)" "unprognostic (5.49e-2)" "unprognostic (1.35e-2)" "unprognostic (2.44e-1)" "unprognostic (1.84e-1)" "unprognostic (2.11e-3)" "unprognostic (3.59e-1)" "unprognostic (1.59e-1)" "unprognostic (1.21e-1)" "unprognostic (2.35e-1)" "unprognostic (1.66e-3)" "unprognostic (1.05e-2)" ZNF630 "BC037316, dJ54B20.2, FLJ20573, MGC138344" ENSG00000221994 "Zinc finger protein 630" Q2M218 X 47983356-48071658 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001053, HPA068130" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 41: Basophils - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 7: Non-specific - Transcription" Nucleoplasm Cytosol "HPA001053: , HPA068130: " "unprognostic (3.09e-3)" "unprognostic (1.33e-2)" "unprognostic (1.13e-1)" "unprognostic (1.20e-1)" "unprognostic (4.40e-2)" "unprognostic (1.72e-1)" "unprognostic (3.06e-3)" "unprognostic (3.48e-2)" "unprognostic (2.28e-2)" "unprognostic (3.67e-2)" "unprognostic (3.82e-2)" "unprognostic (6.42e-3)" "unprognostic (2.04e-1)" "unprognostic (4.58e-2)" "unprognostic (9.73e-3)" "unprognostic (2.37e-1)" "unprognostic (1.18e-1)" "unprognostic (1.94e-1)" "unprognostic (7.46e-2)" "unprognostic (3.79e-2)" "unprognostic (9.76e-2)" "unprognostic (6.82e-2)" "unprognostic (7.53e-2)" "unprognostic (3.74e-1)" "unprognostic (2.27e-1)" "unprognostic (7.56e-2)" "unprognostic (3.23e-2)" "unprognostic (1.66e-1)" "unprognostic (8.11e-2)" "unprognostic (2.37e-1)" ZNF638 "MGC26130, NP220, ZFML, Zfp638" ENSG00000075292 "Zinc finger protein 638" Q14966 2 71276561-71435069 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Myonuclei: 1055.7;Oligodendrocytes: 947.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pancreas - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036784, HPA057395" Supported Approved Nucleoplasm,Vesicles NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 31: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 55: Myocytes - Oxidative muscle function" 37 Nucleoplasm Vesicles "HPA036784: , HPA057395: " "unprognostic (6.88e-2)" "unprognostic (7.21e-3)" "unprognostic (2.32e-1)" "unprognostic (6.21e-3)" "unprognostic (3.05e-1)" "unprognostic (3.91e-1)" "unprognostic (2.03e-1)" "unprognostic (1.67e-3)" "unprognostic (3.54e-2)" "unprognostic (2.04e-2)" "potential prognostic favorable (7.33e-5)" "unprognostic (2.41e-3)" "unprognostic (1.26e-1)" "unprognostic (2.08e-3)" "unprognostic (4.97e-1)" "unprognostic (7.40e-2)" "unprognostic (3.84e-1)" "unprognostic (9.70e-2)" "unprognostic (5.64e-2)" "unprognostic (7.73e-2)" "unprognostic (1.28e-1)" "unprognostic (3.93e-2)" "unprognostic (3.37e-3)" "unprognostic (2.25e-1)" "unprognostic (1.19e-1)" "unprognostic (2.48e-1)" "unprognostic (2.06e-2)" "unprognostic (2.02e-1)" "unprognostic (1.08e-2)" "unprognostic (5.22e-2)" "unprognostic (2.53e-1)" ZNF639 "ANC-2H01, ZASC1" ENSG00000121864 "Zinc finger protein 639" Q9UID6 3 179323031-179338583 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049023, HPA052163" Uncertain Supported Nucleoplasm NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 17: Non-specific - RNA processing" 14 Nucleoplasm "HPA049023: , HPA052163: " "unprognostic (9.69e-2)" "unprognostic (8.87e-2)" "unprognostic (2.18e-1)" "unprognostic (9.53e-2)" "unprognostic (6.35e-2)" "unprognostic (3.05e-1)" "unprognostic (2.15e-2)" "unprognostic (1.17e-1)" "unprognostic (1.27e-1)" "unprognostic (5.85e-2)" "potential prognostic favorable (2.00e-4)" "unprognostic (2.13e-2)" "unprognostic (1.51e-1)" "unprognostic (3.49e-3)" "unprognostic (1.98e-3)" "unprognostic (1.40e-2)" "unprognostic (7.85e-3)" "unprognostic (9.62e-2)" "unprognostic (1.99e-3)" "unprognostic (3.65e-1)" "unprognostic (8.27e-2)" "unprognostic (3.19e-3)" "unprognostic (9.71e-3)" "unprognostic (1.40e-2)" "unprognostic (6.24e-3)" "unprognostic (2.38e-1)" "unprognostic (2.10e-2)" "unprognostic (1.21e-1)" "unprognostic (1.77e-1)" "unprognostic (9.96e-3)" "unprognostic (2.95e-1)" ZNF641 FLJ31295 ENSG00000167528 "Zinc finger protein 641" Q96N77 12 48337180-48351414 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 57.1;Neutrophils: 75.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035189, HPA075069" Uncertain Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 24: Neutrophils - Innate immunity signal integration" Nucleoplasm "Nucleoli, Cytosol" "HPA035189: , HPA075069: " "unprognostic (8.38e-3)" "unprognostic (2.43e-1)" "unprognostic (2.85e-1)" "unprognostic (6.24e-2)" "unprognostic (2.68e-2)" "unprognostic (1.61e-1)" "unprognostic (6.26e-2)" "unprognostic (2.11e-2)" "unprognostic (7.01e-2)" "unprognostic (2.13e-1)" "unprognostic (1.34e-3)" "unprognostic (4.93e-3)" "unprognostic (8.23e-2)" "unprognostic (4.50e-3)" "unprognostic (3.07e-2)" "unprognostic (2.02e-2)" "unprognostic (4.02e-1)" "unprognostic (1.65e-1)" "unprognostic (1.58e-2)" "unprognostic (3.33e-1)" "unprognostic (2.02e-1)" "unprognostic (3.21e-3)" "unprognostic (3.17e-2)" "unprognostic (8.79e-2)" "unprognostic (1.38e-1)" "unprognostic (2.76e-1)" "unprognostic (1.41e-2)" "unprognostic (1.07e-1)" "unprognostic (1.66e-1)" "unprognostic (7.05e-2)" "unprognostic (3.29e-1)" ZNF644 "BM-005, KIAA1221, MGC60165, MGC70410" ENSG00000122482 "Zinc finger protein 644" Q9H582 1 90915298-91022272 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in all" 5 "Gallbladder cancer: 104.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057795 Uncertain Uncertain Vesicles NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 51: Secretory epithelial cells - Mixed function" 34 Vesicles "HPA057795: " "unprognostic (3.93e-2)" "unprognostic (6.21e-2)" "unprognostic (4.29e-2)" "unprognostic (9.29e-2)" "unprognostic (2.23e-3)" "unprognostic (2.61e-1)" "unprognostic (9.82e-3)" "unprognostic (2.36e-2)" "unprognostic (1.32e-2)" "unprognostic (1.93e-1)" "unprognostic (6.63e-2)" "unprognostic (1.63e-2)" "unprognostic (1.73e-1)" "unprognostic (1.35e-2)" "unprognostic (2.15e-1)" "unprognostic (3.28e-2)" "unprognostic (1.94e-1)" "unprognostic (2.03e-2)" "unprognostic (4.81e-2)" "unprognostic (1.93e-1)" "unprognostic (2.47e-1)" "unprognostic (7.18e-2)" "unprognostic (2.28e-2)" "unprognostic (2.04e-1)" "unprognostic (3.45e-1)" "unprognostic (1.16e-1)" "unprognostic (1.36e-1)" "unprognostic (3.08e-1)" "unprognostic (1.94e-1)" "unprognostic (3.33e-2)" "unprognostic (2.48e-2)" ZNF646 KIAA0296 ENSG00000167395 "Zinc finger protein 646" O15015 16 31074422-31084196 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 24.3" "Cell type enhanced" "Detected in many" "Early spermatids: 38.0;Late primary spermatocytes: 28.0;Neutrophils: 34.0;Tuft cells: 34.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 25.2" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042364, HPA066468" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 47: Testis - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 54: Non-specific - Transcription" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 4 "Nucleoplasm, Plasma membrane, Cytosol" "HPA042364: , HPA066468: " "unprognostic (5.01e-2)" "unprognostic (1.94e-2)" "unprognostic (1.90e-1)" "unprognostic (2.54e-2)" "unprognostic (6.55e-2)" "unprognostic (2.31e-1)" "unprognostic (2.15e-1)" "potential prognostic favorable (1.51e-5)" "unprognostic (4.72e-3)" "unprognostic (7.43e-2)" "potential prognostic favorable (6.79e-4)" "unprognostic (3.12e-2)" "unprognostic (2.11e-1)" "potential prognostic unfavorable (3.95e-6)" "unprognostic (1.69e-1)" "unprognostic (1.05e-1)" "unprognostic (8.38e-3)" "unprognostic (2.30e-1)" "unprognostic (4.26e-2)" "unprognostic (5.40e-2)" "unprognostic (2.12e-1)" "unprognostic (2.74e-1)" "unprognostic (1.58e-2)" "unprognostic (2.01e-1)" "unprognostic (1.89e-2)" "unprognostic (3.69e-1)" "unprognostic (2.03e-1)" "unprognostic (9.36e-2)" "unprognostic (1.72e-1)" "unprognostic (6.46e-2)" "unprognostic (4.20e-2)" ZNF648 FLJ46813 ENSG00000179930 "Zinc finger protein 648" Q5T619 1 182054570-182061712 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 7.1;Differentiating spermatogonia: 1.2;Early spermatids: 1.0;Kupffer cells: 1.0;Pituitary stem cells: 1.8;Respiratory deuterosomal cells: 3.1;Respiratory secretory cells: 1.0;Sertoli cells: 1.1;Somatotrophs: 1.7;Undifferentiated spermatogonia: 1.9" "Group enriched" "Detected in some" 6 "choroid plexus epithelial cell: 1.2;fibroblast: 4.2;LAMP5-LHX6 and Chandelier: 2.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA053897 Uncertain NA NA "Cluster 49: Hindbrain - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 50 "HPA053897: " "unprognostic (1.22e-1)" "unprognostic (1.41e-2)" "unprognostic (1.03e-3)" ZNF649 FLJ12644 ENSG00000198093 "Zinc finger protein 649" Q9BS31 19 51889235-51905040 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Prostatic glandular cells: 20.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" HPA026541 Uncertain NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 9: Non-specific - Receptor signaling" "Cluster 60: Prostate cancer - Unknown function" "Cluster 7: Non-specific - Transcription" 10 "HPA026541: " "unprognostic (6.91e-3)" "unprognostic (2.12e-1)" "unprognostic (4.25e-3)" "unprognostic (1.54e-1)" "unprognostic (1.76e-2)" "unprognostic (2.92e-1)" "unprognostic (6.76e-3)" "unprognostic (1.60e-1)" "unprognostic (2.03e-2)" "unprognostic (3.05e-1)" "validated prognostic favorable (1.39e-6)" "validated prognostic favorable (2.03e-7)" "unprognostic (3.89e-2)" "unprognostic (2.77e-1)" "unprognostic (9.75e-2)" "unprognostic (1.01e-1)" "unprognostic (1.05e-1)" "unprognostic (1.44e-1)" "unprognostic (1.32e-1)" "unprognostic (1.41e-1)" "unprognostic (1.71e-1)" "unprognostic (3.24e-1)" "unprognostic (1.90e-2)" "unprognostic (7.36e-2)" "unprognostic (9.49e-3)" "unprognostic (9.09e-3)" "unprognostic (1.13e-2)" "unprognostic (1.94e-3)" "unprognostic (2.04e-1)" "unprognostic (1.99e-1)" "unprognostic (5.40e-2)" ZNF652 KIAA0924 ENSG00000198740 "Zinc finger protein 652" Q9Y2D9 17 49289206-49362473 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044408 Uncertain Approved Nucleoplasm No No "Cluster 35: Neutrophils - Protein binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 27: Breast cancer - Unknown function" "Cluster 7: Non-specific - Transcription" 1 Nucleoplasm "HPA044408: " "unprognostic (3.92e-2)" "unprognostic (1.18e-1)" "unprognostic (3.13e-1)" "unprognostic (8.53e-2)" "unprognostic (2.72e-2)" "unprognostic (2.69e-2)" "unprognostic (1.48e-1)" "unprognostic (1.15e-1)" "unprognostic (6.17e-2)" "unprognostic (3.13e-1)" "potential prognostic favorable (1.05e-4)" "unprognostic (1.19e-3)" "unprognostic (1.78e-1)" "unprognostic (3.09e-1)" "unprognostic (1.60e-1)" "unprognostic (1.29e-1)" "unprognostic (2.21e-1)" "unprognostic (2.27e-1)" "unprognostic (6.27e-3)" "unprognostic (3.33e-3)" "unprognostic (3.70e-1)" "unprognostic (1.18e-2)" "unprognostic (2.01e-1)" "unprognostic (1.19e-1)" "unprognostic (2.01e-1)" "unprognostic (5.63e-2)" "unprognostic (2.06e-1)" "unprognostic (7.12e-2)" "unprognostic (8.39e-2)" "unprognostic (1.16e-2)" "unprognostic (4.63e-2)" ZNF653 Zip67 ENSG00000161914 "Zinc finger protein 653" Q96CK0 19 11483427-11505839 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 30.7" "Cell type enhanced" "Detected in some" "Fallopian tube ciliated cells: 1.2;Late primary spermatocytes: 1.4;Late spermatids: 5.0;Respiratory ionocytes: 2.5;Undifferentiated spermatogonia: 1.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023631, HPA023635" Uncertain Supported Nucleoplasm NA NA "Cluster 67: Testis - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 23: Non-specific - Transcription" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 5 Nucleoplasm "HPA023631: , HPA023635: " "unprognostic (1.34e-1)" "unprognostic (7.78e-2)" "unprognostic (2.84e-1)" "unprognostic (4.59e-2)" "unprognostic (1.34e-1)" "unprognostic (1.29e-1)" "unprognostic (1.71e-1)" "unprognostic (1.23e-1)" "unprognostic (1.77e-2)" "unprognostic (8.18e-2)" "unprognostic (1.39e-3)" "potential prognostic favorable (1.86e-4)" "unprognostic (4.26e-2)" "unprognostic (2.38e-2)" "unprognostic (1.50e-1)" "unprognostic (1.40e-1)" "unprognostic (1.92e-1)" "unprognostic (9.34e-2)" "unprognostic (1.10e-2)" "unprognostic (4.83e-3)" "unprognostic (1.45e-1)" "unprognostic (7.94e-3)" "unprognostic (8.19e-2)" "unprognostic (1.51e-1)" "unprognostic (2.90e-1)" "unprognostic (2.38e-1)" "unprognostic (2.16e-3)" "unprognostic (3.76e-2)" "unprognostic (1.75e-3)" "unprognostic (1.85e-1)" "unprognostic (2.48e-1)" ZNF654 "FLJ10997, FLJ21142" ENSG00000175105 "Zinc finger protein 654" Q8IZM8 3 88059255-88144660 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 9.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036172, HPA036173, HPA049262, HPA077939" Uncertain Approved "Nucleoplasm,Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 55: Non-specific - Transcription" "Cluster 13: Non-specific - Mixed function" "Cluster 7: Non-specific - Transcription" Microtubules "Nucleoplasm, Cytokinetic bridge, Mitotic spindle" "HPA036172: , HPA036173: , HPA049262: , HPA077939: " "unprognostic (3.57e-2)" "unprognostic (3.18e-2)" "unprognostic (1.05e-1)" "unprognostic (1.69e-2)" "unprognostic (2.91e-1)" "unprognostic (3.78e-3)" "unprognostic (3.51e-1)" "unprognostic (3.92e-1)" "unprognostic (2.44e-2)" "unprognostic (2.83e-3)" "potential prognostic favorable (1.70e-6)" "unprognostic (6.49e-3)" "unprognostic (3.53e-2)" "unprognostic (8.24e-2)" "unprognostic (1.96e-1)" "unprognostic (1.80e-2)" "unprognostic (1.13e-1)" "unprognostic (3.01e-2)" "unprognostic (2.18e-1)" "unprognostic (1.42e-1)" "unprognostic (6.61e-2)" "unprognostic (7.42e-3)" "unprognostic (2.67e-2)" "unprognostic (3.10e-3)" "unprognostic (3.92e-3)" "unprognostic (3.59e-1)" "unprognostic (2.44e-1)" "unprognostic (2.56e-1)" "unprognostic (1.59e-1)" "unprognostic (4.66e-2)" "unprognostic (2.90e-1)" ZNF655 "VIK, VIK-1" ENSG00000197343 "Zinc finger protein 655" Q8N720 7 99558406-99576453 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 18.4;Epicardial cells: 9.1;Esophageal apical cells: 7.2" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029534, HPA050750" Uncertain Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 127 Nucleoplasm "Plasma membrane" "HPA029534: , HPA050750: " "unprognostic (1.03e-3)" "unprognostic (3.53e-2)" "unprognostic (5.91e-2)" "unprognostic (1.69e-3)" "unprognostic (2.62e-1)" "unprognostic (7.27e-3)" "unprognostic (6.08e-2)" "unprognostic (1.67e-1)" "unprognostic (1.56e-1)" "unprognostic (1.90e-3)" "potential prognostic favorable (3.60e-6)" "unprognostic (6.15e-2)" "unprognostic (1.37e-2)" "unprognostic (2.03e-2)" "unprognostic (4.03e-2)" "unprognostic (2.25e-1)" "unprognostic (3.90e-3)" "unprognostic (6.48e-2)" "unprognostic (2.37e-1)" "unprognostic (1.32e-1)" "unprognostic (1.15e-1)" "unprognostic (3.12e-3)" "unprognostic (2.15e-3)" "unprognostic (8.67e-2)" "unprognostic (1.65e-1)" "unprognostic (1.38e-2)" "unprognostic (1.34e-2)" "unprognostic (4.24e-1)" "unprognostic (2.23e-1)" "unprognostic (1.13e-1)" "unprognostic (6.16e-2)" ZNF658 "DKFZp572C163, FLJ32813, MGC35232" ENSG00000274349 "Zinc finger protein 658" Q5TYW1 9 66856426-66932141 "Predicted intracellular proteins, Transcription factors" "Ribosome biogenesis, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 27.3;Distal convoluted tubule cells: 19.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 11 "neutrophil: 28.1" "Lineage enriched" "Detected in many" 11 "granulocytes: 28.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047730, HPA048668" Uncertain Approved Nucleoplasm No No "Cluster 21: Neutrophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 55: Myocytes - Oxidative muscle function" 3 Nucleoplasm "HPA047730: , HPA048668: " "unprognostic (8.33e-3)" "unprognostic (1.00e-1)" "unprognostic (1.07e-1)" "unprognostic (9.33e-2)" "unprognostic (4.09e-2)" "unprognostic (1.29e-1)" "unprognostic (4.19e-3)" "unprognostic (1.55e-2)" "unprognostic (6.59e-2)" "potential prognostic favorable (4.69e-4)" "unprognostic (2.35e-3)" "unprognostic (1.03e-1)" "unprognostic (2.86e-2)" "unprognostic (1.52e-2)" "unprognostic (6.86e-2)" "unprognostic (4.16e-1)" "unprognostic (4.47e-2)" "unprognostic (1.54e-1)" "potential prognostic favorable (4.16e-4)" "unprognostic (7.50e-2)" "unprognostic (1.08e-3)" "unprognostic (2.70e-1)" "unprognostic (2.02e-1)" "unprognostic (5.08e-3)" "unprognostic (7.83e-2)" "unprognostic (8.77e-3)" "unprognostic (2.86e-1)" ZNF66 "FLJ16537, ZNF66P" ENSG00000160229 "Zinc finger protein 66" Q6ZN08 19 20776304-20809995 "Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 23.2;Brain inhibitory neurons: 23.9;Microglia: 28.1;Papillary tip epithelial cells: 44.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 16.5" "Lineage enriched" "Detected in all" 4 "granulocytes: 16.5" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 40: Non-specific - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 102: Non-specific - Mixed function" "unprognostic (5.44e-2)" "unprognostic (4.40e-2)" "unprognostic (8.77e-3)" "potential prognostic unfavorable (1.07e-4)" "unprognostic (1.07e-2)" "unprognostic (3.57e-2)" "unprognostic (4.40e-3)" "unprognostic (7.88e-2)" "potential prognostic unfavorable (4.23e-4)" "unprognostic (4.71e-2)" "unprognostic (5.20e-2)" "unprognostic (2.49e-1)" "unprognostic (1.66e-1)" "unprognostic (3.87e-1)" "unprognostic (1.40e-1)" "unprognostic (1.49e-1)" "unprognostic (2.56e-1)" "unprognostic (2.49e-1)" "unprognostic (8.84e-3)" "unprognostic (2.37e-2)" "unprognostic (2.53e-1)" "unprognostic (4.14e-2)" "unprognostic (4.52e-2)" "unprognostic (9.08e-2)" "unprognostic (1.39e-1)" "unprognostic (1.47e-1)" "unprognostic (1.82e-1)" "unprognostic (1.64e-2)" "unprognostic (1.64e-1)" ZNF660 FLJ36870 ENSG00000144792 "Zinc finger protein 660" Q6AZW8 3 44578223-44599694 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cholangiocytes: 2.0;Early spermatids: 3.8;Epididymal efferent duct absorptive cells: 1.2;Hematopoietic stem cells: 1.9;Mast cells: 1.0;Megakaryocyte progenitors: 1.5;Müller glia: 1.5;Myosatellite cells: 1.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 3.7;testis cancer: 2.5" "Low region specificity" "Detected in all" HPA029705 Uncertain Uncertain "Nucleoli fibrillar center,Cytosol" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 4 "Nucleoli fibrillar center, Cytosol" "HPA029705: " "unprognostic (1.75e-1)" "unprognostic (1.57e-1)" "unprognostic (1.30e-1)" "unprognostic (1.89e-1)" "unprognostic (5.86e-2)" "unprognostic (1.42e-2)" "unprognostic (7.12e-2)" "unprognostic (1.51e-1)" ZNF662 FLJ45880 ENSG00000182983 "Zinc finger protein 662" Q6ZS27 3 42906142-42919334 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Early primary spermatocytes: 8.5;Esophageal apical cells: 4.9;Hematopoietic stem cells: 3.4;Late primary spermatocytes: 4.3;Late spermatids: 5.3;Oocytes: 13.8;Undifferentiated spermatogonia: 3.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA039116, HPA040377" Uncertain Approved "Nuclear bodies,Cytosol" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 64: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 1 "Nuclear bodies, Cytosol" "HPA039116: , HPA040377: " "potential prognostic favorable (1.48e-4)" "unprognostic (1.05e-1)" "unprognostic (1.09e-1)" "unprognostic (1.04e-1)" "potential prognostic favorable (1.78e-4)" "unprognostic (9.41e-2)" "unprognostic (2.32e-1)" "unprognostic (3.49e-2)" "unprognostic (1.69e-1)" "unprognostic (1.26e-2)" "unprognostic (2.53e-3)" "unprognostic (2.99e-3)" "potential prognostic favorable (9.21e-4)" "unprognostic (4.94e-1)" "unprognostic (2.58e-1)" "unprognostic (2.43e-1)" "unprognostic (7.03e-2)" "unprognostic (1.82e-1)" "unprognostic (1.34e-1)" "unprognostic (1.18e-1)" "unprognostic (9.23e-2)" "unprognostic (2.44e-1)" "unprognostic (8.05e-3)" "unprognostic (7.73e-3)" "unprognostic (4.21e-3)" "unprognostic (3.71e-2)" "unprognostic (1.78e-1)" "unprognostic (3.29e-2)" ZNF664 "DKFZp761B128, ZFOC1, ZNF176" ENSG00000179195 "Zinc finger protein 664" Q8N3J9 12 123971845-124015439 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 35.9;Late spermatids: 63.7" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047846 Approved Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 4 Nucleoplasm "HPA047846: " "unprognostic (8.45e-2)" "unprognostic (1.71e-1)" "unprognostic (1.20e-1)" "unprognostic (1.94e-1)" "unprognostic (8.89e-3)" "unprognostic (1.14e-1)" "unprognostic (4.55e-2)" "unprognostic (2.56e-1)" "unprognostic (2.42e-1)" "unprognostic (4.32e-3)" "potential prognostic favorable (5.84e-5)" "unprognostic (1.01e-2)" "unprognostic (2.07e-1)" "unprognostic (1.72e-3)" "unprognostic (4.60e-3)" "unprognostic (3.47e-1)" "unprognostic (2.29e-1)" "unprognostic (2.43e-2)" "unprognostic (9.32e-3)" "unprognostic (2.55e-1)" "unprognostic (6.09e-2)" "unprognostic (5.11e-1)" "unprognostic (7.85e-2)" "unprognostic (1.25e-1)" "unprognostic (4.56e-3)" "unprognostic (5.58e-2)" "unprognostic (1.20e-1)" "unprognostic (6.92e-2)" "unprognostic (2.42e-1)" "unprognostic (1.06e-1)" "unprognostic (1.23e-2)" ZNF665 "FLJ14345, ZFP160L" ENSG00000197497 "Zinc finger protein 665" Q9H7R5 19 53159213-53193386 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in some" HPA023437 Uncertain Approved "Nuclear membrane" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" "Nuclear membrane" "HPA023437: " "unprognostic (8.27e-3)" "unprognostic (6.14e-2)" "unprognostic (4.70e-1)" "unprognostic (4.51e-3)" "unprognostic (4.94e-1)" "unprognostic (1.60e-1)" "unprognostic (3.72e-2)" "unprognostic (1.65e-1)" "unprognostic (1.72e-1)" "unprognostic (4.09e-3)" "unprognostic (3.09e-2)" "unprognostic (2.04e-2)" "unprognostic (1.59e-2)" "unprognostic (9.44e-2)" "unprognostic (2.85e-2)" "unprognostic (7.07e-2)" "unprognostic (7.50e-3)" "unprognostic (1.91e-1)" "unprognostic (4.56e-2)" "unprognostic (3.05e-2)" "unprognostic (9.95e-3)" ZNF667 FLJ14011 ENSG00000198046 "Zinc finger protein 667" Q5HYK9 19 56439325-56478065 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 21.6" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 42.5;Brain excitatory neurons: 45.1;Brain inhibitory neurons: 47.4;Lactotrophs: 113.0;Other brain neurons: 48.2;Somatotrophs: 110.6;Thyrotrophs: 45.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 3.0;NK-cell: 2.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030731, HPA046673" Uncertain Approved Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 65: Brain - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 1 Nucleoplasm "HPA030731: , HPA046673: " "unprognostic (5.67e-2)" "unprognostic (4.20e-2)" "unprognostic (4.75e-2)" "unprognostic (1.35e-2)" "unprognostic (8.00e-2)" "unprognostic (8.98e-2)" "unprognostic (2.30e-1)" "unprognostic (2.30e-2)" "unprognostic (8.50e-2)" "potential prognostic favorable (7.13e-5)" "unprognostic (8.66e-2)" "unprognostic (7.48e-3)" "unprognostic (9.95e-2)" "unprognostic (1.56e-1)" "unprognostic (1.63e-1)" "unprognostic (2.16e-1)" "unprognostic (2.33e-1)" "unprognostic (4.85e-3)" "unprognostic (3.63e-2)" "unprognostic (1.31e-2)" "unprognostic (1.12e-1)" "unprognostic (2.70e-1)" "unprognostic (1.47e-1)" "unprognostic (1.40e-1)" "unprognostic (1.81e-2)" ZNF668 FLJ13479 ENSG00000167394 "Zinc finger protein 668" Q96K58 16 31060843-31074240 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Early spermatids: 81.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043048 Uncertain Approved "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 115 "Nucleoli, Nucleoli rim" Nucleoplasm "HPA043048: " "unprognostic (3.22e-2)" "unprognostic (5.18e-2)" "potential prognostic favorable (7.65e-4)" "unprognostic (1.91e-2)" "unprognostic (5.09e-2)" "unprognostic (3.82e-2)" "unprognostic (5.61e-2)" "unprognostic (9.08e-3)" "unprognostic (1.64e-3)" "unprognostic (2.73e-2)" "potential prognostic unfavorable (1.29e-4)" "unprognostic (2.68e-2)" "unprognostic (4.54e-2)" "potential prognostic unfavorable (3.03e-4)" "unprognostic (6.16e-3)" "unprognostic (1.02e-1)" "unprognostic (2.00e-2)" "unprognostic (8.44e-2)" "unprognostic (9.16e-3)" "unprognostic (2.56e-1)" "unprognostic (2.20e-1)" "unprognostic (9.42e-2)" "unprognostic (4.85e-2)" "unprognostic (7.43e-3)" "unprognostic (2.87e-1)" "unprognostic (5.44e-2)" "unprognostic (2.58e-1)" "unprognostic (1.93e-1)" "unprognostic (3.74e-1)" "unprognostic (3.36e-3)" "unprognostic (4.10e-2)" ZNF669 FLJ12606 ENSG00000188295 "Zinc finger protein 669" Q96BR6 1 247099962-247104372 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 21.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" HPA044043 Uncertain NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 45: Non-specific - Nuclear processes" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 19 "HPA044043: " "unprognostic (4.84e-3)" "unprognostic (2.61e-2)" "unprognostic (4.96e-2)" "unprognostic (5.29e-3)" "unprognostic (3.65e-1)" "unprognostic (2.52e-1)" "unprognostic (2.12e-1)" "unprognostic (1.12e-2)" "unprognostic (7.20e-2)" "unprognostic (3.57e-3)" "unprognostic (2.78e-3)" "unprognostic (4.61e-2)" "unprognostic (4.45e-2)" "unprognostic (3.70e-2)" "unprognostic (6.07e-2)" "unprognostic (3.78e-2)" "unprognostic (1.26e-1)" "unprognostic (1.72e-1)" "unprognostic (7.90e-2)" "unprognostic (3.88e-2)" "unprognostic (8.45e-2)" "unprognostic (1.58e-1)" "unprognostic (1.89e-2)" "unprognostic (2.11e-1)" "unprognostic (2.61e-2)" "unprognostic (3.79e-2)" "unprognostic (3.73e-2)" "unprognostic (1.24e-1)" "unprognostic (1.35e-1)" "unprognostic (8.20e-3)" "unprognostic (6.82e-2)" ZNF670 MGC12466 ENSG00000277462 "Zinc finger protein 670" Q9BS34 1 247034637-247078811 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Early spermatids: 4.8;Paneth cells: 3.9" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells" HPA003142 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 18: Non-specific - Translation" "Cluster 61: Non-specific - Transcription" "Cluster 2: Neurons - Nucleosome" "Cluster 4: Non-specific - Transcription" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 27 Nucleoplasm Cytosol "HPA003142: " "unprognostic (9.20e-2)" "unprognostic (5.04e-2)" "unprognostic (1.07e-1)" "unprognostic (8.87e-2)" "unprognostic (2.92e-1)" "unprognostic (6.16e-1)" "unprognostic (2.77e-1)" "unprognostic (2.99e-1)" "potential prognostic favorable (9.94e-5)" "unprognostic (1.22e-2)" "unprognostic (2.05e-1)" "unprognostic (7.04e-2)" "unprognostic (8.91e-2)" "potential prognostic unfavorable (6.75e-6)" "unprognostic (3.36e-2)" "unprognostic (8.34e-2)" "unprognostic (3.03e-2)" "unprognostic (4.50e-2)" "unprognostic (1.10e-2)" "unprognostic (4.23e-3)" "unprognostic (1.79e-1)" "unprognostic (1.58e-1)" "unprognostic (1.93e-1)" "unprognostic (1.52e-1)" "unprognostic (4.72e-2)" "unprognostic (3.01e-1)" ZNF671 FLJ23506 ENSG00000083814 "Zinc finger protein 671" Q8TAW3 19 57719751-57727624 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 26.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA046099, HPA056043" Uncertain Supported Nucleoplasm NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 2: Neurons - Nucleosome" "Cluster 4: Non-specific - Transcription" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" Nucleoplasm "HPA046099: , HPA056043: " "unprognostic (7.92e-2)" "unprognostic (1.28e-2)" "unprognostic (1.61e-1)" "unprognostic (2.25e-1)" "unprognostic (1.68e-1)" "unprognostic (4.96e-1)" "unprognostic (3.86e-1)" "validated prognostic favorable (1.09e-5)" "validated prognostic favorable (1.73e-4)" "potential prognostic favorable (3.33e-5)" "unprognostic (1.05e-1)" "potential prognostic favorable (6.47e-4)" "unprognostic (1.01e-3)" "unprognostic (2.67e-1)" "unprognostic (1.37e-1)" "unprognostic (1.15e-1)" "unprognostic (1.70e-1)" "unprognostic (3.71e-2)" "potential prognostic favorable (1.68e-4)" "unprognostic (1.85e-1)" "unprognostic (1.10e-1)" "unprognostic (2.15e-1)" "unprognostic (8.53e-2)" "unprognostic (4.50e-1)" "unprognostic (2.70e-1)" "unprognostic (1.21e-1)" "unprognostic (1.42e-1)" ZNF672 FLJ22301 ENSG00000171161 "Zinc finger protein 672" Q499Z4 1 248838210-248849517 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 93.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055779, HPA062506" Approved Enhanced Nucleoplasm Yes Yes "Cluster 2: Dendritic cells - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 5 Nucleoplasm "HPA055779: , HPA062506: " "unprognostic (5.55e-3)" "unprognostic (1.22e-3)" "unprognostic (1.78e-1)" "unprognostic (1.43e-1)" "unprognostic (6.40e-2)" "unprognostic (5.16e-3)" "unprognostic (2.70e-1)" "unprognostic (5.13e-3)" "unprognostic (3.18e-3)" "unprognostic (1.35e-1)" "potential prognostic favorable (6.50e-4)" "unprognostic (1.12e-1)" "unprognostic (7.13e-2)" "unprognostic (1.36e-2)" "unprognostic (1.86e-3)" "unprognostic (3.96e-2)" "unprognostic (3.04e-2)" "unprognostic (1.12e-1)" "unprognostic (2.02e-1)" "unprognostic (4.26e-2)" "unprognostic (5.05e-3)" "potential prognostic favorable (3.37e-4)" "unprognostic (9.67e-2)" "unprognostic (4.19e-2)" "unprognostic (4.93e-2)" "unprognostic (2.05e-2)" "unprognostic (3.84e-1)" "unprognostic (6.96e-2)" "unprognostic (8.77e-2)" "potential prognostic unfavorable (1.38e-4)" "unprognostic (8.54e-2)" ZNF674 "MRX92, ZNF673B" ENSG00000251192 "Zinc finger protein 674" Q2M3X9 X 46497725-46545457 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 58.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Prostate - Prostate glandular cells, Spleen - Endothelial cells" "HPA031026, HPA065295" Uncertain Supported Nucleoplasm NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 42: Retina - Visual perception" "Cluster 31: Non-specific - Transcription" "Cluster 13: Non-specific - Mixed function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 1 Nucleoplasm "HPA031026: , HPA065295: " "unprognostic (1.76e-2)" "unprognostic (2.43e-3)" "unprognostic (1.88e-1)" "unprognostic (6.41e-3)" "unprognostic (9.73e-2)" "unprognostic (1.24e-1)" "unprognostic (2.91e-1)" "unprognostic (1.07e-1)" "unprognostic (4.78e-2)" "unprognostic (7.97e-3)" "unprognostic (4.51e-2)" "unprognostic (2.48e-3)" "unprognostic (3.28e-1)" "unprognostic (8.36e-2)" "unprognostic (8.13e-2)" "unprognostic (1.57e-1)" "unprognostic (7.27e-3)" "unprognostic (1.09e-1)" "unprognostic (2.81e-1)" "potential prognostic unfavorable (5.94e-4)" "unprognostic (3.91e-2)" "unprognostic (3.76e-3)" "unprognostic (1.65e-1)" "unprognostic (3.05e-2)" "unprognostic (3.10e-3)" "unprognostic (4.05e-2)" "unprognostic (1.57e-1)" "unprognostic (3.11e-1)" "unprognostic (1.85e-2)" "unprognostic (8.99e-2)" ZNF675 "TBZF, TIZ" ENSG00000197372 "Zinc finger protein 675" Q8TD23 19 23525631-23687220 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 109.5;Late primary spermatocytes: 111.7;Late spermatids: 305.8;Renal collecting duct principal cells: 86.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 37.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 40: Non-specific - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 109: Neurons - Neuronal signaling" 4 "unprognostic (2.33e-2)" "unprognostic (1.70e-2)" "unprognostic (1.67e-1)" "unprognostic (1.72e-1)" "unprognostic (9.65e-2)" "unprognostic (1.82e-2)" "unprognostic (1.09e-1)" "unprognostic (3.79e-2)" "unprognostic (1.25e-1)" "unprognostic (1.73e-2)" "potential prognostic favorable (8.03e-4)" "unprognostic (2.49e-3)" "unprognostic (1.13e-1)" "unprognostic (4.47e-1)" "unprognostic (1.15e-2)" "unprognostic (4.18e-2)" "unprognostic (1.96e-1)" "unprognostic (5.41e-2)" "unprognostic (6.83e-2)" "unprognostic (1.12e-2)" "unprognostic (1.81e-2)" "unprognostic (2.31e-1)" "unprognostic (1.09e-2)" "unprognostic (1.37e-1)" "potential prognostic favorable (5.98e-4)" "unprognostic (1.03e-1)" "unprognostic (1.52e-2)" "unprognostic (2.19e-2)" "unprognostic (1.82e-1)" "unprognostic (2.29e-2)" "unprognostic (6.45e-2)" ZNF676 ENSG00000196109 "Zinc finger protein 676" Q8N7Q3 19 22179089-22215801 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 13.6;Distal convoluted tubule cells: 12.7;Early primary spermatocytes: 15.6;Early spermatids: 18.9;Late primary spermatocytes: 29.5;Oligodendrocyte progenitor cells: 12.2;Oligodendrocytes: 39.3;Oocytes: 13.8;Other brain neurons: 22.6;Pituicytes/FSCs: 15.2;Podocytes: 12.9;Renal collecting duct intercalated cells: 13.1;Renal collecting duct principal cells: 17.2;Renal connecting tubule cells: 20.1" "Cell type enhanced" "Detected in many" "fibroblast: 51.7;hippocampal CA4: 53.2;oligodendrocyte: 60.7" "Cancer enriched" "Detected in some" 6 "Testicular Germ Cell Tumor (TCGA): 15.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "testis cancer: 1.5" "Spleen - Endothelial cells" NA NA "Cluster 21: Testis - Mixed function" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 4: Non-specific - Transcription" "Cluster 98: Neurons - Neurotransmission & signaling" "unprognostic (1.24e-2)" "potential prognostic favorable (6.95e-4)" "unprognostic (4.87e-1)" "unprognostic (7.61e-3)" "unprognostic (3.50e-2)" "unprognostic (2.16e-2)" "unprognostic (1.38e-1)" "unprognostic (3.94e-2)" ZNF677 MGC48625 ENSG00000197928 "Zinc finger protein 677" Q86XU0 19 53235381-53254898 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 42.4" "Group enriched" "Detected in many" 5 "Early spermatids: 783.5;Late primary spermatocytes: 198.5;Late spermatids: 538.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Spleen - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" HPA023106 Approved Approved Nucleoplasm,Centrosome NA NA "Cluster 24: Non-specific - Transcription" "Cluster 57: Testis - Spermatogenesis" "Cluster 55: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" Nucleoplasm Centrosome "HPA023106: " "unprognostic (2.51e-2)" "unprognostic (8.19e-3)" "unprognostic (1.57e-1)" "unprognostic (2.55e-3)" "unprognostic (3.02e-2)" "unprognostic (2.04e-1)" "unprognostic (2.62e-2)" "unprognostic (2.77e-1)" "unprognostic (8.16e-3)" "unprognostic (5.19e-2)" "validated prognostic favorable (1.16e-5)" "validated prognostic favorable (3.59e-5)" "unprognostic (6.22e-2)" "unprognostic (2.97e-1)" "unprognostic (8.01e-3)" "unprognostic (2.34e-1)" "unprognostic (2.71e-1)" "unprognostic (2.88e-1)" "unprognostic (1.00e-1)" "unprognostic (1.33e-1)" "unprognostic (1.08e-1)" "unprognostic (2.57e-1)" "unprognostic (1.03e-1)" "unprognostic (9.75e-2)" "unprognostic (2.30e-2)" "unprognostic (4.70e-3)" "unprognostic (6.86e-2)" "unprognostic (2.89e-1)" "unprognostic (1.63e-1)" "unprognostic (2.45e-1)" ZNF678 MGC42493 ENSG00000181450 "Zinc finger protein 678" Q5SXM1 1 227563543-227677443 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" HPA028507 Uncertain Approved Nucleoplasm,Nucleoli,Cytosol Yes No "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" Nucleoli "Nucleoplasm, Cytosol" "HPA028507: " "unprognostic (4.06e-2)" "unprognostic (4.19e-2)" "unprognostic (2.81e-1)" "unprognostic (1.54e-2)" "unprognostic (8.65e-2)" "unprognostic (2.31e-1)" "unprognostic (3.48e-2)" "unprognostic (5.47e-3)" "unprognostic (3.07e-3)" "unprognostic (1.27e-3)" "unprognostic (8.41e-3)" "unprognostic (3.78e-1)" "unprognostic (1.31e-1)" "unprognostic (3.13e-2)" "unprognostic (2.39e-2)" "unprognostic (5.24e-3)" "unprognostic (3.77e-3)" "unprognostic (1.34e-1)" "unprognostic (2.11e-1)" "unprognostic (1.42e-1)" "unprognostic (8.50e-3)" "unprognostic (2.96e-1)" "unprognostic (2.78e-2)" "unprognostic (2.58e-1)" "unprognostic (3.11e-2)" "unprognostic (2.12e-2)" "unprognostic (3.30e-2)" "unprognostic (2.92e-2)" "unprognostic (3.03e-1)" "unprognostic (3.37e-2)" "unprognostic (1.56e-1)" ZNF679 MGC42415 ENSG00000197123 "Zinc finger protein 679" Q8IYX0 7 64228474-64266931 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 10 "testis: 1.0" "Group enriched" "Detected in some" 10 "Early spermatids: 32.0;Late primary spermatocytes: 8.2;Late spermatids: 8.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 1: Neuronal - Visual perception" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 4 "unprognostic (3.72e-2)" ZNF680 FLJ90430 ENSG00000173041 "Zinc finger protein 680" Q8NEM1 7 64519878-64563075 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 135.9;Cardiomyocytes: 169.5;Myonuclei: 270.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" HPA003173 Approved Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 76: Non-specific - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 55: Myocytes - Oxidative muscle function" Nucleoplasm "HPA003173: " "unprognostic (1.59e-1)" "unprognostic (5.50e-2)" "unprognostic (1.06e-1)" "unprognostic (5.34e-2)" "unprognostic (2.41e-1)" "unprognostic (1.62e-1)" "unprognostic (7.57e-2)" "unprognostic (3.40e-1)" "unprognostic (4.62e-2)" "unprognostic (6.54e-3)" "unprognostic (1.23e-1)" "unprognostic (8.86e-2)" "unprognostic (4.80e-2)" "unprognostic (2.06e-1)" "unprognostic (1.25e-1)" "unprognostic (2.30e-1)" "unprognostic (8.57e-2)" "unprognostic (2.22e-1)" "unprognostic (2.84e-1)" "unprognostic (3.73e-2)" "unprognostic (3.56e-3)" "unprognostic (2.71e-2)" "potential prognostic unfavorable (3.78e-4)" "unprognostic (2.20e-1)" "unprognostic (6.35e-2)" "unprognostic (1.69e-1)" "unprognostic (2.74e-3)" "unprognostic (1.43e-1)" "unprognostic (4.19e-1)" "unprognostic (5.90e-2)" "unprognostic (1.56e-1)" ZNF681 FLJ31526 ENSG00000196172 "Zinc finger protein 681" Q96N22 19 23739195-23758891 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 21.1;Esophageal apical cells: 37.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 6.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Spermatocytes" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 61: Non-specific - Transcription" "Cluster 2: Neurons - Nucleosome" "Cluster 4: Non-specific - Transcription" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" "potential prognostic favorable (6.01e-7)" "unprognostic (2.75e-1)" "unprognostic (1.55e-1)" "unprognostic (1.96e-2)" "unprognostic (1.95e-1)" "unprognostic (2.26e-1)" "unprognostic (1.01e-1)" "unprognostic (7.43e-3)" "unprognostic (3.85e-3)" "unprognostic (1.23e-2)" "unprognostic (5.39e-2)" "unprognostic (9.00e-2)" "unprognostic (2.53e-2)" "unprognostic (2.10e-3)" "unprognostic (1.51e-1)" "unprognostic (2.65e-1)" "unprognostic (3.69e-2)" "unprognostic (9.21e-2)" "unprognostic (3.06e-3)" "unprognostic (3.46e-2)" "unprognostic (1.82e-1)" "unprognostic (3.13e-1)" "unprognostic (5.64e-1)" "unprognostic (4.21e-2)" "unprognostic (2.57e-1)" ZNF682 BC39498_3 ENSG00000197124 "Zinc finger protein 682" O95780 19 19997058-20039505 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 123.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 30.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" HPA055998 Uncertain Uncertain "Golgi apparatus" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 34: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 1 "Golgi apparatus" "HPA055998: " "potential prognostic favorable (1.30e-4)" "unprognostic (8.28e-3)" "unprognostic (2.21e-1)" "unprognostic (2.68e-1)" "unprognostic (7.23e-2)" "unprognostic (1.54e-2)" "unprognostic (4.95e-2)" "unprognostic (3.53e-3)" "potential prognostic unfavorable (5.12e-4)" "unprognostic (8.39e-2)" "unprognostic (2.19e-1)" "unprognostic (1.14e-1)" "unprognostic (3.07e-2)" "unprognostic (1.94e-1)" "potential prognostic favorable (1.41e-5)" "unprognostic (4.41e-2)" "unprognostic (4.48e-3)" "unprognostic (3.78e-2)" "unprognostic (9.39e-3)" "unprognostic (6.81e-2)" "unprognostic (1.11e-3)" "unprognostic (5.20e-2)" "unprognostic (1.75e-1)" "unprognostic (1.36e-1)" "unprognostic (2.68e-1)" "unprognostic (1.09e-2)" "unprognostic (9.20e-2)" "unprognostic (2.97e-1)" "unprognostic (3.60e-1)" "unprognostic (3.29e-1)" ZNF683 "Hobit, MGC33414" ENSG00000176083 "Zinc finger protein 683" Q8IZ20 1 26361634-26374522 "Predicted intracellular proteins, Transcription factors" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 76.5" "Group enriched" "Detected in some" 11 "Early spermatids: 640.0;Late spermatids: 639.4" "Cell type enriched" "Detected in single" 67 "leukocyte: 46.4" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 11.4" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "gdT-cell: 172.8;memory CD8 T-cell: 113.0" "Lineage enriched" "Detected in many" 15 "T-cells: 172.8" "Cancer enriched" "Detected in single" 5 "Leukemia: 2.2" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Kidney - T-cells, Lung - T-cells, Pancreas - T-cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - T-cells" "Not detected" "Not detected" HPA023865 Uncertain NA NA "Cluster 1: T-cells - Unknown function" "Cluster 21: Testis - Mixed function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 5 "HPA023865: " "unprognostic (3.40e-2)" "unprognostic (8.20e-3)" "unprognostic (5.09e-2)" "unprognostic (2.84e-2)" "unprognostic (4.58e-2)" "unprognostic (6.64e-2)" "unprognostic (5.25e-3)" "unprognostic (1.81e-2)" "unprognostic (1.40e-3)" "unprognostic (8.75e-2)" "unprognostic (4.26e-2)" "unprognostic (5.26e-3)" "unprognostic (4.61e-2)" "unprognostic (1.37e-1)" "unprognostic (4.33e-3)" "unprognostic (2.42e-2)" "unprognostic (2.32e-1)" "unprognostic (1.49e-2)" "unprognostic (1.66e-2)" "unprognostic (1.46e-1)" "unprognostic (1.58e-1)" "unprognostic (7.18e-2)" "unprognostic (4.89e-3)" "unprognostic (5.98e-2)" "unprognostic (4.13e-1)" "unprognostic (1.26e-2)" "unprognostic (3.63e-2)" ZNF684 MGC27466 ENSG00000117010 "Zinc finger protein 684" Q5T5D7 1 40531573-40548167 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 12.0" "Cell type enhanced" "Detected in many" "Renal collecting duct intercalated cells: 35.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" HPA059153 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 32: Basophils - Transcription" "Cluster 76: Non-specific - Metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 37: Non-specific - mRNA processing" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 6 Cytosol Nucleoplasm "HPA059153: " "unprognostic (1.73e-1)" "unprognostic (1.71e-1)" "unprognostic (3.36e-1)" "unprognostic (1.47e-1)" "unprognostic (6.65e-2)" "unprognostic (4.78e-3)" "unprognostic (9.02e-2)" "unprognostic (1.11e-1)" "unprognostic (1.35e-3)" "unprognostic (6.11e-2)" "potential prognostic favorable (1.20e-5)" "unprognostic (8.06e-3)" "potential prognostic favorable (1.37e-5)" "unprognostic (8.79e-2)" "potential prognostic favorable (1.13e-4)" "unprognostic (3.54e-3)" "unprognostic (4.83e-2)" "unprognostic (3.11e-2)" "unprognostic (1.57e-1)" "unprognostic (2.96e-1)" "unprognostic (1.43e-1)" "potential prognostic favorable (7.99e-4)" "unprognostic (1.45e-1)" "unprognostic (2.15e-1)" "unprognostic (3.73e-2)" "unprognostic (1.19e-1)" "unprognostic (1.76e-1)" "unprognostic (1.33e-2)" "unprognostic (2.02e-1)" "unprognostic (4.11e-2)" "unprognostic (2.55e-2)" ZNF687 KIAA1441 ENSG00000143373 "Zinc finger protein 687" Q8N1G0 1 151281618-151292176 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 28.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 13.5" "Group enriched" "Detected in many" 8 "granulocytes: 13.5;monocytes: 4.5" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021193, HPA023948" Approved Enhanced Nucleoplasm NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 24: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 45: Non-specific - Nuclear processes" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 26 Nucleoplasm "HPA021193: , HPA023948: " "unprognostic (1.39e-1)" "unprognostic (1.96e-1)" "unprognostic (8.84e-2)" "unprognostic (3.02e-1)" "unprognostic (1.11e-1)" "unprognostic (9.78e-2)" "unprognostic (1.44e-1)" "potential prognostic favorable (1.84e-4)" "unprognostic (2.00e-2)" "unprognostic (8.34e-2)" "potential prognostic favorable (7.92e-4)" "unprognostic (5.94e-2)" "unprognostic (1.13e-1)" "unprognostic (1.71e-2)" "unprognostic (1.20e-1)" "unprognostic (1.77e-1)" "unprognostic (2.92e-2)" "unprognostic (7.01e-2)" "unprognostic (1.24e-2)" "unprognostic (5.78e-2)" "unprognostic (8.07e-2)" "unprognostic (2.23e-2)" "unprognostic (1.02e-1)" "unprognostic (4.51e-2)" "unprognostic (5.90e-2)" "unprognostic (2.35e-1)" "unprognostic (4.25e-1)" "unprognostic (3.02e-1)" "unprognostic (2.19e-1)" "unprognostic (1.24e-1)" "unprognostic (2.98e-1)" ZNF688 ENSG00000229809 "Zinc finger protein 688" P0C7X2 16 30569672-30572734 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "Late spermatids: 967.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048922 Uncertain Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 67: Testis - Mixed function" "Cluster 25: Non-specific - Transcription" "Cluster 54: Non-specific - Transcription" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 35 Nucleoplasm "Plasma membrane, Cell Junctions" "HPA048922: " "unprognostic (3.34e-1)" "unprognostic (3.30e-2)" "unprognostic (8.10e-2)" "unprognostic (1.61e-1)" "unprognostic (2.09e-1)" "unprognostic (9.35e-2)" "unprognostic (2.83e-2)" "potential prognostic favorable (2.30e-4)" "unprognostic (6.03e-3)" "unprognostic (2.22e-1)" "unprognostic (1.71e-3)" "unprognostic (2.11e-1)" "unprognostic (8.00e-3)" "unprognostic (2.17e-1)" "unprognostic (1.42e-1)" "unprognostic (8.74e-2)" "unprognostic (2.84e-1)" "unprognostic (1.04e-1)" "unprognostic (1.02e-1)" "unprognostic (2.52e-1)" "unprognostic (9.68e-2)" "unprognostic (1.21e-2)" "unprognostic (1.68e-1)" "unprognostic (4.65e-2)" "unprognostic (2.03e-1)" "unprognostic (1.14e-1)" "unprognostic (1.03e-1)" "unprognostic (3.21e-2)" "unprognostic (2.03e-1)" "unprognostic (1.50e-2)" "unprognostic (4.56e-3)" ZNF689 "FLJ90415, TIPUH1" ENSG00000156853 "Zinc finger protein 689" Q96CS4 16 30602558-30624012 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 18.2" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 55.2;Early spermatids: 44.6;Late primary spermatocytes: 151.7;Late spermatids: 83.1;Oocytes: 46.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054095, HPA055385" Approved Approved "Nucleoplasm,Nucleoli fibrillar center" No No "Cluster 33: Non-specific - ATP binding" "Cluster 39: Testis - Nuclear processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 54: Non-specific - Transcription" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 8 "Nucleoplasm, Nucleoli fibrillar center" "HPA054095: , HPA055385: " "unprognostic (1.04e-1)" "unprognostic (1.68e-1)" "unprognostic (2.95e-2)" "unprognostic (1.53e-1)" "unprognostic (4.80e-2)" "unprognostic (9.34e-2)" "unprognostic (3.25e-1)" "unprognostic (2.13e-3)" "unprognostic (1.20e-1)" "unprognostic (5.96e-2)" "potential prognostic favorable (5.49e-5)" "unprognostic (5.49e-2)" "unprognostic (2.21e-1)" "unprognostic (7.89e-2)" "unprognostic (1.12e-1)" "unprognostic (8.03e-2)" "unprognostic (1.59e-1)" "unprognostic (2.53e-1)" "unprognostic (1.03e-2)" "unprognostic (1.16e-1)" "unprognostic (1.00e-1)" "unprognostic (3.44e-3)" "unprognostic (6.15e-2)" "unprognostic (3.02e-1)" "unprognostic (2.12e-2)" "unprognostic (3.25e-2)" "unprognostic (8.94e-3)" "unprognostic (2.22e-1)" "unprognostic (1.57e-1)" "unprognostic (1.32e-1)" "unprognostic (3.74e-1)" ZNF69 Cos5 ENSG00000198429 "Zinc finger protein 69" Q9UC07 19 11887782-11914329 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Loop of henle epithelial cells: 113.2;Proximal tubule cells: 164.0;Sertoli cells: 115.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 12.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" HPA047845 Approved Uncertain Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 76: Non-specific - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 2 Nucleoplasm "HPA047845: " "unprognostic (1.57e-2)" "unprognostic (2.73e-1)" "unprognostic (7.32e-2)" "unprognostic (1.08e-1)" "unprognostic (7.32e-2)" "unprognostic (1.14e-1)" "unprognostic (6.47e-2)" "unprognostic (4.65e-1)" "unprognostic (1.80e-1)" "potential prognostic favorable (9.40e-5)" "unprognostic (2.60e-3)" "potential prognostic favorable (4.65e-4)" "unprognostic (8.76e-2)" "unprognostic (3.65e-2)" "unprognostic (1.79e-2)" "unprognostic (5.74e-3)" "unprognostic (2.07e-1)" "unprognostic (3.51e-1)" "unprognostic (4.86e-2)" "unprognostic (4.08e-2)" "unprognostic (7.15e-2)" "unprognostic (6.04e-2)" "unprognostic (2.32e-2)" "unprognostic (2.76e-3)" "unprognostic (1.26e-1)" "unprognostic (1.07e-2)" "unprognostic (2.78e-1)" "unprognostic (8.67e-2)" "unprognostic (1.62e-1)" "unprognostic (2.58e-1)" ZNF691 Zfp691 ENSG00000164011 "Zinc finger protein 691" Q5VV52 1 42846573-42852477 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglia: 23.7" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 26.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062527 Approved Approved Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 22: Epididymis - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 37: Non-specific - mRNA processing" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 2 Nucleoplasm "Nucleoli, Vesicles" "HPA062527: " "unprognostic (2.42e-1)" "unprognostic (2.50e-1)" "unprognostic (1.82e-2)" "unprognostic (2.28e-1)" "unprognostic (7.58e-2)" "unprognostic (6.41e-2)" "unprognostic (3.32e-1)" "unprognostic (2.29e-2)" "unprognostic (9.41e-2)" "unprognostic (2.33e-2)" "potential prognostic favorable (1.83e-4)" "unprognostic (8.77e-3)" "unprognostic (2.97e-3)" "potential prognostic unfavorable (1.69e-6)" "unprognostic (3.72e-1)" "unprognostic (1.16e-3)" "unprognostic (2.85e-1)" "unprognostic (2.63e-2)" "unprognostic (2.02e-1)" "unprognostic (3.35e-1)" "unprognostic (2.10e-2)" "unprognostic (9.80e-3)" "unprognostic (1.98e-1)" "unprognostic (6.30e-2)" "unprognostic (1.18e-1)" "unprognostic (1.78e-1)" "unprognostic (2.76e-2)" "unprognostic (3.29e-1)" "unprognostic (1.54e-1)" "unprognostic (2.05e-2)" "unprognostic (8.94e-2)" ZNF692 "AREBP, FLJ20531, Zfp692" ENSG00000171163 "Zinc finger protein 692" Q9BU19 1 248850006-248859144 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 76.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059337, HPA062792" Uncertain Enhanced Nucleoplasm,Nucleoli NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 35: RS4;11 - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 4 "Nucleoplasm, Nucleoli" "HPA059337: , HPA062792: " "unprognostic (2.10e-1)" "unprognostic (3.04e-1)" "unprognostic (6.04e-2)" "unprognostic (1.98e-1)" "unprognostic (2.75e-2)" "potential prognostic unfavorable (4.15e-5)" "unprognostic (3.36e-1)" "unprognostic (3.15e-3)" "unprognostic (1.43e-1)" "unprognostic (1.86e-2)" "potential prognostic unfavorable (2.68e-5)" "unprognostic (5.60e-2)" "unprognostic (1.97e-2)" "potential prognostic unfavorable (7.18e-4)" "unprognostic (1.69e-1)" "unprognostic (9.88e-2)" "potential prognostic unfavorable (9.88e-5)" "unprognostic (1.71e-2)" "unprognostic (2.65e-2)" "unprognostic (1.68e-1)" "unprognostic (1.93e-2)" "unprognostic (2.32e-3)" "unprognostic (2.05e-2)" "unprognostic (3.69e-2)" "unprognostic (3.68e-1)" "unprognostic (1.40e-1)" "unprognostic (6.92e-2)" "unprognostic (1.46e-2)" "unprognostic (3.94e-2)" "unprognostic (2.31e-1)" "unprognostic (1.75e-1)" ZNF695 SBZF3 ENSG00000197472 "Zinc finger protein 695" Q8IW36 1 246945547-247008093 "Predicted intracellular proteins, Transcription factors" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Epididymal clear cells: 2.0;Erythrocyte progenitors: 1.6;Kupffer cells: 1.0;Late primary spermatocytes: 1.1;Oocytes: 4.6" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 5.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Mitotic cells (Minor salivary gland), Stomach - Mitotic cells (Stomach)" HPA024743 Uncertain Approved "Nuclear speckles" NA NA "Cluster 51: Neurons - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 41: Oocytes - Oogenesis" 1 "Nuclear speckles" "HPA024743: " "unprognostic (2.61e-2)" "unprognostic (1.91e-1)" "unprognostic (2.71e-2)" "potential prognostic unfavorable (2.30e-5)" "unprognostic (1.39e-1)" "unprognostic (1.86e-1)" "unprognostic (7.00e-3)" "unprognostic (2.08e-1)" "unprognostic (4.76e-2)" "unprognostic (1.26e-3)" "unprognostic (4.35e-3)" "unprognostic (5.52e-2)" "potential prognostic favorable (4.02e-4)" "unprognostic (2.93e-1)" "unprognostic (8.23e-2)" "unprognostic (5.09e-1)" "unprognostic (6.96e-2)" ZNF696 FLJ14129 ENSG00000185730 "Zinc finger protein 696" Q9H7X3 8 143289676-143299952 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 15.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057855, HPA072473" Uncertain Approved Nucleoplasm,Nucleoli No No "Cluster 30: Non-specific - DNA binding" "Cluster 64: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 38 Nucleoplasm Nucleoli "HPA057855: , HPA072473: " "unprognostic (6.82e-2)" "unprognostic (2.55e-2)" "unprognostic (1.87e-1)" "potential prognostic unfavorable (1.58e-4)" "unprognostic (4.06e-2)" "unprognostic (1.50e-1)" "unprognostic (3.71e-1)" "unprognostic (2.71e-3)" "unprognostic (1.29e-1)" "unprognostic (2.53e-3)" "unprognostic (1.00e-1)" "unprognostic (4.05e-2)" "unprognostic (1.60e-1)" "unprognostic (4.35e-3)" "unprognostic (5.49e-2)" "unprognostic (4.71e-1)" "unprognostic (1.63e-2)" "unprognostic (2.55e-1)" "unprognostic (4.72e-3)" "unprognostic (3.12e-1)" "unprognostic (1.44e-1)" "unprognostic (3.97e-3)" "unprognostic (2.78e-2)" "unprognostic (1.40e-1)" "unprognostic (3.13e-1)" "unprognostic (2.48e-1)" "unprognostic (1.43e-1)" "unprognostic (2.46e-1)" "unprognostic (3.68e-1)" "unprognostic (1.86e-2)" "unprognostic (1.36e-1)" ZNF697 MGC45731 ENSG00000143067 "Zinc finger protein 697" Q5TEC3 1 119619377-119648266 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 26.7;monocytes: 42.2;Proximal tubule cells: 61.7;Somatotrophs: 44.8;Syncytiotrophoblasts: 48.4" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 19.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 30.0" "Pituitary gland - Somatotropes, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049933 Uncertain Approved Nucleoplasm NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 53: Neurons - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 4 Nucleoplasm "HPA049933: " "unprognostic (1.86e-1)" "unprognostic (1.28e-1)" "unprognostic (1.57e-1)" "unprognostic (1.73e-2)" "unprognostic (2.58e-1)" "unprognostic (4.08e-2)" "unprognostic (4.43e-1)" "unprognostic (5.45e-3)" "unprognostic (9.54e-3)" "unprognostic (2.14e-1)" "validated prognostic favorable (5.24e-8)" "validated prognostic favorable (7.65e-5)" "unprognostic (1.24e-1)" "potential prognostic unfavorable (7.06e-4)" "unprognostic (1.22e-1)" "potential prognostic unfavorable (3.98e-6)" "unprognostic (1.18e-1)" "unprognostic (1.86e-1)" "unprognostic (1.65e-2)" "unprognostic (2.17e-1)" "unprognostic (1.69e-2)" "unprognostic (2.36e-2)" "unprognostic (4.32e-2)" "unprognostic (9.27e-2)" "unprognostic (5.40e-2)" "unprognostic (1.51e-1)" "unprognostic (1.41e-1)" "unprognostic (3.56e-3)" "unprognostic (1.46e-1)" "unprognostic (1.46e-2)" "unprognostic (1.28e-1)" ZNF699 "FLJ38144, hang" ENSG00000196110 "Zinc finger protein 699" Q32M78 19 9291140-9309838 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Deafness, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Retinal horizontal cells: 40.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" HPA058287 Uncertain NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 9 "HPA058287: " "unprognostic (1.03e-3)" "unprognostic (7.75e-2)" "unprognostic (1.60e-1)" "unprognostic (1.84e-1)" "unprognostic (2.63e-1)" "unprognostic (1.06e-1)" "unprognostic (1.35e-2)" "unprognostic (5.25e-2)" "unprognostic (1.59e-2)" "unprognostic (9.54e-2)" "validated prognostic favorable (1.15e-5)" "validated prognostic favorable (9.36e-4)" "potential prognostic favorable (4.85e-4)" "unprognostic (1.71e-1)" "unprognostic (1.75e-2)" "unprognostic (1.27e-2)" "unprognostic (5.80e-2)" "unprognostic (9.24e-2)" "unprognostic (6.76e-3)" "unprognostic (7.18e-2)" "unprognostic (3.30e-2)" "unprognostic (1.08e-1)" "unprognostic (3.84e-1)" "unprognostic (7.57e-2)" "unprognostic (1.70e-1)" "unprognostic (2.34e-2)" "unprognostic (1.03e-1)" ZNF7 "HF.16, KOX4" ENSG00000147789 "Zinc finger protein 7" P17097 8 144827518-144847509 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059090 Approved Approved Mitochondria NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 24: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 4 Mitochondria "HPA059090: " "unprognostic (2.51e-2)" "unprognostic (1.85e-2)" "unprognostic (3.80e-1)" "unprognostic (9.73e-3)" "unprognostic (8.23e-2)" "unprognostic (2.90e-2)" "unprognostic (3.76e-1)" "unprognostic (2.82e-1)" "unprognostic (3.12e-1)" "unprognostic (1.74e-2)" "unprognostic (6.33e-2)" "unprognostic (3.12e-2)" "unprognostic (6.00e-2)" "unprognostic (2.23e-2)" "unprognostic (3.71e-1)" "unprognostic (8.94e-2)" "unprognostic (2.11e-2)" "unprognostic (1.10e-1)" "unprognostic (8.15e-2)" "unprognostic (1.90e-2)" "unprognostic (9.41e-3)" "unprognostic (3.17e-1)" "potential prognostic unfavorable (1.12e-4)" "unprognostic (1.34e-3)" "unprognostic (1.82e-1)" "unprognostic (3.61e-1)" "unprognostic (1.91e-2)" "unprognostic (2.53e-2)" "unprognostic (3.88e-1)" "unprognostic (7.92e-3)" "unprognostic (1.02e-1)" ZNF70 "Cos17, MGC48959" ENSG00000187792 "Zinc finger protein 70" Q9UC06 22 23738682-23751112 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 25.8;Myosatellite cells: 15.8;Retinal horizontal cells: 16.0;Thymic myoid cells: 15.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 1.7" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Prostate - Fibroblasts" "Low region specificity" "Detected in all" HPA018821 Uncertain Approved Cytosol NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 6: Leukemia - Signal transduction" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 2 Cytosol "HPA018821: " "unprognostic (2.81e-3)" "unprognostic (1.33e-2)" "unprognostic (2.58e-1)" "unprognostic (1.03e-2)" "unprognostic (1.12e-1)" "unprognostic (1.58e-1)" "unprognostic (4.94e-2)" "unprognostic (2.24e-1)" "unprognostic (2.98e-2)" "unprognostic (1.86e-1)" "unprognostic (2.41e-1)" "unprognostic (1.22e-2)" "unprognostic (1.61e-1)" "unprognostic (3.99e-2)" "unprognostic (1.20e-1)" "unprognostic (1.30e-2)" "unprognostic (3.23e-3)" "unprognostic (1.35e-1)" "unprognostic (1.37e-1)" "unprognostic (1.53e-2)" "unprognostic (4.41e-2)" "unprognostic (2.50e-2)" "unprognostic (4.54e-2)" "unprognostic (1.06e-1)" "unprognostic (2.05e-2)" "unprognostic (1.17e-1)" "unprognostic (1.78e-1)" "unprognostic (2.29e-1)" ZNF700 DKFZp434I1610 ENSG00000196757 "Zinc finger protein 700" Q9H0M5 19 11925068-11950773 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 2.9;Gastric chief cells: 2.2;Innate lymphoid cells: 2.1;Lacrimal acinar cells: 2.7;Platelets: 2.8" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA047845 Uncertain Uncertain Nucleoplasm NA NA "Cluster 32: Basophils - Transcription" "Cluster 49: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 20: Non-specific - Transcription regulation" Nucleoplasm "HPA047845: " "potential prognostic favorable (2.05e-4)" "unprognostic (2.73e-1)" "unprognostic (2.11e-1)" "unprognostic (1.62e-1)" "unprognostic (3.50e-2)" "unprognostic (6.39e-2)" "unprognostic (6.41e-2)" "unprognostic (8.51e-2)" "potential prognostic favorable (5.43e-5)" "potential prognostic unfavorable (7.45e-4)" "unprognostic (2.81e-2)" "unprognostic (1.57e-1)" "unprognostic (2.87e-2)" "unprognostic (3.57e-2)" "unprognostic (1.06e-2)" "unprognostic (2.20e-1)" "unprognostic (5.35e-2)" "unprognostic (1.75e-1)" "unprognostic (4.46e-2)" "unprognostic (1.04e-1)" "unprognostic (1.33e-1)" "unprognostic (1.23e-1)" "unprognostic (8.09e-3)" "unprognostic (1.70e-2)" "unprognostic (3.89e-3)" "unprognostic (4.23e-2)" "unprognostic (3.88e-2)" "unprognostic (8.36e-2)" "unprognostic (1.53e-1)" "unprognostic (2.58e-1)" "unprognostic (7.10e-2)" ZNF701 FLJ10891 ENSG00000167562 "Zinc finger protein 701" Q9NV72 19 52555822-52587174 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA005532 Uncertain Approved "Nucleoplasm,Centriolar satellite" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 6 Nucleoplasm "Centriolar satellite" "HPA005532: " "unprognostic (6.02e-3)" "unprognostic (4.32e-2)" "unprognostic (1.59e-1)" "unprognostic (8.29e-2)" "unprognostic (2.09e-1)" "unprognostic (6.23e-2)" "unprognostic (2.72e-1)" "unprognostic (2.38e-1)" "unprognostic (1.02e-2)" "potential prognostic unfavorable (1.76e-4)" "validated prognostic favorable (5.16e-4)" "validated prognostic favorable (9.92e-4)" "unprognostic (3.36e-2)" "unprognostic (7.61e-3)" "unprognostic (2.90e-1)" "unprognostic (1.23e-1)" "unprognostic (3.34e-2)" "unprognostic (1.26e-2)" "unprognostic (9.59e-2)" "unprognostic (1.87e-1)" "unprognostic (1.74e-2)" "unprognostic (1.88e-1)" "unprognostic (3.37e-2)" "unprognostic (1.75e-1)" "unprognostic (3.39e-2)" "unprognostic (5.53e-2)" "potential prognostic unfavorable (3.55e-4)" "unprognostic (1.68e-1)" "unprognostic (3.91e-1)" "unprognostic (3.83e-3)" "unprognostic (7.54e-2)" ZNF703 "FLJ14299, NLZ1, ZEPPO1, ZNF503L, Zpo1" ENSG00000183779 "Zinc finger protein 703" Q9H7S9 8 37695782-37700019 "Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 104.7" "Cell type enriched" "Detected in many" 4 "Syncytiotrophoblasts: 569.4" "Cell type enhanced" "Detected in many" "ependymal cell: 28.3;pericyte: 47.2;vascular associated smooth muscle cell: 34.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "intermediate monocyte: 3.3;non-classical monocyte: 4.3" "Lineage enriched" "Detected in single" 12 "monocytes: 4.3" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023930, CAB068249" Supported NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 24: Non-specific - Transcription" "Cluster 43: Hindbrain - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 5 "CAB068249: , HPA023930: " "unprognostic (1.55e-2)" "unprognostic (1.29e-1)" "unprognostic (3.26e-1)" "unprognostic (2.06e-1)" "unprognostic (1.55e-2)" "unprognostic (1.19e-1)" "unprognostic (3.47e-1)" "unprognostic (5.69e-2)" "unprognostic (1.99e-1)" "unprognostic (1.45e-1)" "unprognostic (5.76e-3)" "unprognostic (3.25e-2)" "unprognostic (4.32e-2)" "unprognostic (1.77e-2)" "unprognostic (1.58e-2)" "unprognostic (3.13e-1)" "unprognostic (3.42e-1)" "unprognostic (1.52e-2)" "unprognostic (1.58e-2)" "unprognostic (1.42e-1)" "unprognostic (8.68e-3)" "unprognostic (2.40e-1)" "unprognostic (2.07e-1)" "unprognostic (6.36e-2)" "unprognostic (2.30e-1)" "unprognostic (1.18e-1)" "unprognostic (9.46e-2)" "unprognostic (2.99e-2)" "unprognostic (2.14e-1)" "unprognostic (4.44e-2)" "unprognostic (6.18e-3)" ZNF704 "FLJ16218, Gig1" ENSG00000164684 "Zinc finger protein 704" Q6ZNC4 8 80628451-80874781 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bergmann glia: 428.2;Oligodendrocyte progenitor cells: 470.7;Renal connecting tubule cells: 466.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 23.1" "Minor Salivary Gland - Smooth muscle cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024285, HPA024302" Uncertain Approved Nucleoplasm NA NA "Cluster 70: Non-specific - Protein processing" "Cluster 6: Non-specific - Immune response" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 5 Nucleoplasm "HPA024285: , HPA024302: " "unprognostic (7.43e-2)" "unprognostic (3.16e-2)" "unprognostic (1.33e-1)" "unprognostic (1.18e-1)" "unprognostic (1.99e-1)" "unprognostic (2.85e-1)" "unprognostic (9.95e-2)" "unprognostic (1.91e-3)" "unprognostic (1.76e-1)" "unprognostic (9.80e-2)" "validated prognostic favorable (3.48e-10)" "validated prognostic favorable (1.54e-4)" "unprognostic (7.78e-2)" "unprognostic (3.23e-1)" "unprognostic (5.77e-2)" "unprognostic (5.57e-3)" "unprognostic (3.83e-1)" "unprognostic (1.03e-2)" "unprognostic (8.84e-3)" "unprognostic (1.79e-1)" "unprognostic (1.97e-1)" "unprognostic (2.28e-1)" "unprognostic (1.78e-2)" "unprognostic (6.58e-2)" "unprognostic (1.63e-1)" "unprognostic (7.60e-2)" "unprognostic (3.65e-1)" "unprognostic (5.77e-2)" "unprognostic (2.10e-1)" "unprognostic (1.50e-1)" "unprognostic (1.93e-1)" ZNF705A FLJ16353 ENSG00000196946 "Zinc finger protein 705A" Q6ZN79 12 8157015-8188537 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "epididymis: 2.2" "Group enriched" "Detected in some" 8 "Early spermatids: 6.0;Late primary spermatocytes: 2.3;Late spermatids: 3.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Glioblastoma Multiforme (TCGA): 2.8;Ovary Serous Cystadenocarcinoma (TCGA): 1.4;Testicular Germ Cell Tumor (TCGA): 1.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" "unprognostic (2.92e-1)" "unprognostic (1.82e-1)" "unprognostic (2.16e-1)" "unprognostic (4.95e-2)" "unprognostic (4.95e-2)" "unprognostic (1.30e-1)" ZNF705B ENSG00000215356 "Zinc finger protein 705B" P0CI00 8 7926337-7952413 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "Early spermatids: 6.0;Late spermatids: 3.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" ZNF705D ENSG00000215343 "Zinc finger protein 705D" P0CH99 8 12089338-12115516 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 11 "epididymis: 3.1" "Cell type enhanced" "Detected in single" "Epididymal principal cells: 1.4" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 18 "Testicular Germ Cell Tumor (TCGA): 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" "unprognostic (2.15e-1)" ZNF705G ENSG00000215372 "Zinc finger protein 705G" A8MUZ8 8 7355517-7385558 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "Early spermatids: 33.8;Late spermatids: 31.6" "Cell type enhanced" "Detected in single" "oligodendrocyte: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" NA NA "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" ZNF706 HSPC038 ENSG00000120963 "Zinc finger protein 706" Q9Y5V0 8 101177878-101206193 "Predicted intracellular proteins" "Translation regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 836.0;Esophageal suprabasal cells: 829.9;Late spermatids: 1689.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042793 Approved "Plasma membrane" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 70: Non-specific - Protein processing" "Cluster 34: Non-specific - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 85: Squamous epithelial cells - Keratinization" "Plasma membrane" "HPA042793: " "unprognostic (6.04e-2)" "unprognostic (3.53e-3)" "unprognostic (2.44e-2)" "unprognostic (3.38e-3)" "unprognostic (1.94e-1)" "unprognostic (1.13e-2)" "unprognostic (3.29e-3)" "unprognostic (4.18e-2)" "unprognostic (1.94e-1)" "unprognostic (9.07e-2)" "potential prognostic unfavorable (7.48e-4)" "unprognostic (7.49e-2)" "potential prognostic unfavorable (1.85e-7)" "unprognostic (1.05e-3)" "unprognostic (4.00e-2)" "unprognostic (4.79e-3)" "unprognostic (6.81e-2)" "unprognostic (3.77e-1)" "unprognostic (1.20e-1)" "unprognostic (5.60e-2)" "unprognostic (3.37e-1)" "unprognostic (2.10e-2)" "unprognostic (1.23e-2)" "unprognostic (1.22e-1)" "unprognostic (1.59e-1)" "unprognostic (1.76e-1)" "unprognostic (3.43e-1)" "unprognostic (3.75e-1)" "unprognostic (1.16e-1)" "unprognostic (3.59e-1)" "potential prognostic unfavorable (2.49e-4)" ZNF707 ENSG00000181135 "Zinc finger protein 707" Q96C28 8 143684452-143713898 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bergmann glia: 4.1;Brain excitatory neurons: 3.4;Brain inhibitory neurons: 3.0;Choroid plexus epithelial cells: 5.9;Distal convoluted tubule cells: 6.8;Loop of henle epithelial cells: 7.2;Microglia: 5.9;Oligodendrocyte progenitor cells: 3.2;Oligodendrocytes: 3.2;Other brain neurons: 3.8;Papillary tip epithelial cells: 6.2;Podocytes: 9.3;Proximal tubule cells: 7.9;Renal collecting duct intercalated cells: 5.1;Renal collecting duct principal cells: 6.6;Renal connecting tubule cells: 6.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" HPA044991 Approved Approved Nucleoplasm NA NA "Cluster 68: Non-specific - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 40: Non-specific - Unknown function" "Cluster 102: Non-specific - Mixed function" 27 Nucleoplasm "HPA044991: " "unprognostic (3.75e-2)" "unprognostic (4.81e-2)" "unprognostic (2.50e-1)" "unprognostic (4.48e-3)" "unprognostic (1.75e-1)" "unprognostic (1.19e-1)" "unprognostic (3.77e-1)" "potential prognostic favorable (3.52e-4)" "unprognostic (7.28e-2)" "unprognostic (4.12e-2)" "unprognostic (8.61e-3)" "unprognostic (5.96e-2)" "unprognostic (3.42e-1)" "unprognostic (1.54e-3)" "unprognostic (8.03e-2)" "unprognostic (2.64e-1)" "unprognostic (2.31e-2)" "unprognostic (1.72e-3)" "unprognostic (1.28e-1)" "unprognostic (2.54e-2)" "unprognostic (8.79e-2)" "unprognostic (3.38e-1)" "unprognostic (2.36e-3)" "unprognostic (2.14e-1)" "unprognostic (2.61e-1)" "unprognostic (3.96e-1)" "unprognostic (2.22e-1)" "unprognostic (6.73e-2)" "unprognostic (2.49e-1)" "unprognostic (8.77e-2)" "unprognostic (5.72e-2)" ZNF708 "KOX8, ZNF15, ZNF15L1" ENSG00000182141 "Zinc finger protein 708" P17019 19 21291160-21329425 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 277.3;Retinal pigment epithelial cells: 183.3" "Cell type enhanced" "Detected in all" "oligodendrocyte: 377.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 1 "unprognostic (5.59e-3)" "unprognostic (2.36e-2)" "unprognostic (8.62e-2)" "potential prognostic unfavorable (4.58e-4)" "unprognostic (9.61e-2)" "unprognostic (4.12e-2)" "unprognostic (2.64e-2)" "unprognostic (1.18e-1)" "unprognostic (3.61e-2)" "unprognostic (6.53e-3)" "unprognostic (4.98e-2)" "unprognostic (8.12e-3)" "unprognostic (1.39e-2)" "unprognostic (6.79e-2)" "potential prognostic favorable (2.61e-4)" "unprognostic (8.11e-2)" "unprognostic (2.26e-2)" "unprognostic (2.06e-1)" "unprognostic (2.44e-3)" "unprognostic (4.50e-3)" "unprognostic (1.99e-2)" "unprognostic (7.18e-3)" "unprognostic (2.11e-2)" "unprognostic (3.49e-3)" "unprognostic (1.31e-3)" "unprognostic (1.08e-2)" "unprognostic (4.55e-2)" "unprognostic (2.93e-1)" "unprognostic (2.39e-1)" "unprognostic (1.07e-1)" ZNF709 FLJ38281 ENSG00000242852 "Zinc finger protein 709" Q8N972 19 12461184-12513854 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 14.6" "Group enriched" "Detected in some" 5 "Early spermatids: 28.9;Late spermatids: 24.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "HPA045573, HPA053153" Uncertain Approved Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 21: Testis - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 4: Non-specific - Transcription" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" Nucleoplasm "HPA045573: , HPA053153: " "unprognostic (2.53e-2)" "unprognostic (7.53e-2)" "unprognostic (1.22e-1)" "unprognostic (2.79e-2)" "potential prognostic unfavorable (7.66e-5)" "validated prognostic favorable (1.57e-5)" "validated prognostic favorable (6.93e-4)" "unprognostic (3.88e-3)" "potential prognostic favorable (4.77e-8)" "unprognostic (3.04e-1)" "unprognostic (7.70e-3)" "unprognostic (1.19e-2)" "unprognostic (2.83e-2)" "unprognostic (1.55e-3)" "unprognostic (3.60e-1)" "unprognostic (1.07e-1)" "unprognostic (2.06e-1)" "unprognostic (4.62e-2)" "unprognostic (6.97e-2)" ZNF71 "Cos26, EZFIT" ENSG00000197951 "Zinc finger protein 71" Q9NQZ8 19 56595300-56626481 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 6.0;Epididymal principal cells: 2.3;Loop of henle epithelial cells: 4.9;Papillary tip epithelial cells: 3.5;Podocytes: 9.0;Proximal tubule cells: 5.7;Renal collecting duct intercalated cells: 5.3;Renal collecting duct principal cells: 4.5;Renal connecting tubule cells: 5.4;Schwann cells: 2.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Testis - Sertoli cells" "Low region specificity" "Detected in all" HPA018124 Uncertain Approved Nucleoplasm,Nucleoli NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 24: Non-specific - Transcription" "Cluster 29: Forebrain - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 105: Non-specific - Mixed function" 37 Nucleoli Nucleoplasm "HPA018124: " "unprognostic (1.49e-1)" "unprognostic (1.03e-1)" "unprognostic (6.76e-2)" "unprognostic (2.25e-1)" "unprognostic (8.76e-2)" "unprognostic (1.79e-1)" "unprognostic (1.80e-1)" "unprognostic (1.66e-2)" "unprognostic (6.52e-2)" "unprognostic (9.06e-2)" "unprognostic (1.40e-3)" "unprognostic (1.27e-3)" "unprognostic (7.72e-2)" "unprognostic (2.47e-3)" "unprognostic (1.33e-2)" "unprognostic (2.89e-1)" "unprognostic (1.61e-1)" "unprognostic (4.10e-2)" "unprognostic (2.81e-1)" "unprognostic (2.18e-1)" "unprognostic (1.50e-1)" "unprognostic (5.87e-3)" "unprognostic (7.91e-2)" "unprognostic (8.72e-2)" "unprognostic (8.18e-2)" "unprognostic (4.02e-2)" "unprognostic (1.41e-2)" "unprognostic (4.39e-2)" "unprognostic (2.05e-1)" "unprognostic (1.96e-2)" "unprognostic (1.21e-1)" ZNF710 "DKFZp547K1113, FLJ00306, FLJ37393" ENSG00000140548 "Zinc finger protein 710" Q8N1W2 15 90001324-90082206 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 41.7" "Cell type enhanced" "Detected in many" "cDC: 222.9;Macrophages: 202.9;Microglia: 539.9;monocytes: 190.6;Neutrophils: 250.8;Pancreatic acinar cells: 186.4;Tuft cells: 196.0" "Cell type enriched" "Detected in all" 5 "central nervous system macrophage: 675.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 5.7" "Group enriched" "Detected in many" 6 "dendritic cells: 1.4;granulocytes: 1.9;monocytes: 5.7" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells" "Low region specificity" "Detected in all" "HPA030226, HPA030227, HPA030228" Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 8: Pancreas - Proteolysis" "Cluster 27: Non-specific - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 6 Mitochondria Nucleoplasm "HPA030226: , HPA030227: , HPA030228: " "unprognostic (3.81e-2)" "unprognostic (5.06e-3)" "unprognostic (2.01e-1)" "unprognostic (2.56e-2)" "unprognostic (2.29e-1)" "unprognostic (1.11e-1)" "unprognostic (8.90e-2)" "unprognostic (3.61e-2)" "unprognostic (2.69e-2)" "unprognostic (5.11e-2)" "potential prognostic favorable (2.93e-4)" "unprognostic (3.58e-2)" "unprognostic (1.13e-2)" "unprognostic (5.95e-2)" "unprognostic (1.27e-2)" "unprognostic (1.66e-2)" "unprognostic (2.17e-2)" "unprognostic (1.06e-2)" "unprognostic (6.31e-2)" "unprognostic (3.70e-2)" "unprognostic (1.43e-1)" "unprognostic (6.10e-2)" "unprognostic (5.66e-2)" "unprognostic (9.39e-2)" "unprognostic (2.29e-1)" "unprognostic (2.00e-1)" "unprognostic (6.48e-2)" "unprognostic (3.78e-2)" "unprognostic (1.42e-1)" "unprognostic (1.58e-1)" "unprognostic (6.69e-2)" ZNF711 "CMPX1, dJ75N13.1, MRX65, MRX97, Zfp711, ZNF4, ZNF5, ZNF6" ENSG00000147180 "Zinc finger protein 711" Q9Y462 X 85243991-85273362 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 34.9" "Cell type enriched" "Detected in many" 5 "Sertoli cells: 451.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 13.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.3" "Lineage enhanced" "Detected in single" "B-cells: 1.3" "Cancer enhanced" "Detected in many" "Neuroblastoma: 31.8" "Adrenal gland - Adrenal cortex cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030654 Enhanced Approved Nucleoplasm NA NA "Cluster 75: Ovary - Mixed function" "Cluster 14: Neurons - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 6 Nucleoplasm "HPA030654: " "unprognostic (1.33e-2)" "unprognostic (1.01e-1)" "unprognostic (3.62e-1)" "unprognostic (2.81e-1)" "unprognostic (3.36e-1)" "unprognostic (1.34e-1)" "unprognostic (6.06e-2)" "potential prognostic favorable (3.09e-4)" "unprognostic (4.19e-2)" "unprognostic (1.38e-3)" "potential prognostic favorable (2.61e-4)" "unprognostic (2.77e-1)" "unprognostic (1.15e-2)" "unprognostic (4.97e-2)" "unprognostic (1.20e-1)" "unprognostic (1.68e-3)" "unprognostic (2.19e-2)" "unprognostic (7.12e-3)" "unprognostic (1.19e-1)" "unprognostic (3.48e-2)" "unprognostic (8.11e-3)" "unprognostic (5.48e-2)" "unprognostic (1.60e-1)" "unprognostic (9.11e-2)" "unprognostic (9.76e-2)" "unprognostic (1.39e-1)" "unprognostic (7.74e-2)" "unprognostic (1.08e-1)" ZNF713 FLJ39963 ENSG00000178665 "Zinc finger protein 713" Q8N859 7 55887456-55942530 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Autism spectrum disorder" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 22.2;Bergmann glia: 25.6;Brain excitatory neurons: 23.0;Brain inhibitory neurons: 28.9;Choroid plexus epithelial cells: 43.1;Ependymal cells: 59.2;Microglia: 13.0;Oligodendrocyte progenitor cells: 30.2;Oligodendrocytes: 47.4;Other brain neurons: 21.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.8" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.8" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "HPA059425, HPA062887" Uncertain Approved Nucleoli NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 40: Non-specific - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 22: Non-specific - Basic cellular functions" 1 Nucleoli "HPA059425: , HPA062887: " "unprognostic (1.45e-2)" "unprognostic (2.15e-2)" "unprognostic (7.93e-2)" "unprognostic (1.09e-2)" "unprognostic (5.94e-3)" "unprognostic (2.02e-2)" "unprognostic (6.70e-2)" "unprognostic (2.40e-1)" "unprognostic (1.38e-2)" "unprognostic (9.69e-2)" "unprognostic (2.24e-1)" "unprognostic (3.37e-3)" "unprognostic (6.49e-2)" "unprognostic (2.72e-1)" "unprognostic (5.29e-2)" "unprognostic (8.25e-2)" "unprognostic (9.87e-2)" "unprognostic (2.97e-1)" "unprognostic (1.70e-1)" "unprognostic (6.91e-2)" "unprognostic (4.23e-2)" "unprognostic (1.10e-1)" "unprognostic (1.85e-2)" "unprognostic (9.15e-2)" "unprognostic (2.32e-1)" "unprognostic (5.98e-2)" "unprognostic (4.28e-2)" "unprognostic (2.17e-2)" "unprognostic (1.27e-1)" ZNF714 ENSG00000160352 "Zinc finger protein 714" 19 21082159-21125270 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "ovary: 13.9;thyroid gland: 13.4" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 94.1;Esophageal apical cells: 101.6;Retinal pigment epithelial cells: 89.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 61: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 18: Adrenal cortex cells - Steroidogensis" "unprognostic (5.87e-2)" "unprognostic (2.93e-1)" "unprognostic (3.72e-2)" "unprognostic (4.72e-2)" "unprognostic (1.02e-1)" "unprognostic (1.18e-2)" "unprognostic (1.00e-2)" "potential prognostic favorable (9.34e-4)" "unprognostic (8.39e-2)" "unprognostic (1.24e-1)" "unprognostic (1.65e-1)" "unprognostic (3.29e-1)" "unprognostic (1.54e-1)" "unprognostic (7.09e-2)" "unprognostic (7.94e-3)" "unprognostic (1.87e-2)" "unprognostic (1.09e-1)" "unprognostic (5.24e-3)" "potential prognostic unfavorable (1.90e-6)" "unprognostic (2.55e-1)" "unprognostic (2.86e-3)" "unprognostic (7.94e-2)" "unprognostic (4.91e-3)" "unprognostic (1.38e-1)" "unprognostic (2.91e-2)" "unprognostic (1.10e-1)" "unprognostic (5.19e-1)" "unprognostic (5.35e-2)" "unprognostic (2.26e-1)" ZNF716 FLJ46189 ENSG00000182111 "Zinc finger protein 716" A6NP11 7 57450177-57473559 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Differentiating spermatogonia: 9.4;Early primary spermatocytes: 5.0;Early spermatids: 3.4;Late primary spermatocytes: 5.6;Late spermatids: 6.3;Undifferentiated spermatogonia: 3.8" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "Testicular Germ Cell Tumor (TCGA): 5.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 48: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 106: Spermatogonia - Spermatogonial differentiation" "unprognostic (2.70e-1)" ZNF717 "X17, ZNF838" ENSG00000227124 "Zinc finger protein 717" Q9BY31 3 75678660-75785583 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ependymal cells: 115.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA044549 Uncertain Approved "Nucleoplasm,Nuclear bodies,Plasma membrane" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 28: Astrocytes - Homeostasis & neuron support" "Nucleoplasm, Nuclear bodies" "Plasma membrane" "HPA044549: " "unprognostic (3.36e-2)" "unprognostic (2.97e-2)" "unprognostic (1.20e-1)" "unprognostic (7.41e-3)" "unprognostic (1.15e-1)" "unprognostic (1.21e-2)" "unprognostic (2.78e-1)" "unprognostic (3.77e-1)" "unprognostic (3.93e-3)" "unprognostic (3.13e-1)" "unprognostic (6.19e-3)" "unprognostic (6.68e-3)" "potential prognostic favorable (6.87e-5)" "unprognostic (1.45e-2)" "unprognostic (8.89e-2)" "unprognostic (6.88e-2)" "unprognostic (2.53e-1)" "unprognostic (4.27e-2)" "unprognostic (5.14e-2)" "unprognostic (1.17e-1)" "unprognostic (2.60e-1)" "unprognostic (3.14e-1)" "unprognostic (5.68e-2)" "unprognostic (3.72e-2)" "unprognostic (1.57e-2)" "unprognostic (2.46e-1)" "unprognostic (1.36e-1)" "unprognostic (2.12e-1)" "unprognostic (2.77e-2)" "unprognostic (2.20e-1)" "unprognostic (1.61e-1)" ZNF718 FLJ90036 ENSG00000250312 "Zinc finger protein 718" Q3SXZ3 4 124501-202303 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Sertoli cells: 170.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" NA Yes "Cluster 32: Basophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 5 "unprognostic (8.67e-2)" "unprognostic (1.85e-1)" "unprognostic (8.07e-2)" "unprognostic (7.09e-2)" "unprognostic (2.36e-2)" "unprognostic (1.34e-1)" "unprognostic (2.14e-1)" "unprognostic (7.83e-2)" "unprognostic (1.47e-2)" "unprognostic (1.01e-1)" "potential prognostic favorable (1.29e-5)" "unprognostic (4.60e-3)" "unprognostic (1.19e-1)" "unprognostic (4.88e-3)" "unprognostic (2.40e-3)" "unprognostic (8.74e-2)" "unprognostic (1.23e-3)" "unprognostic (1.08e-2)" "unprognostic (1.38e-1)" "unprognostic (1.58e-1)" "unprognostic (1.17e-1)" "unprognostic (2.22e-1)" "unprognostic (3.56e-2)" "unprognostic (1.60e-1)" "unprognostic (2.23e-1)" "unprognostic (2.05e-1)" "unprognostic (1.87e-1)" "unprognostic (2.70e-1)" "unprognostic (2.79e-1)" "unprognostic (8.07e-2)" "unprognostic (4.01e-2)" ZNF721 KIAA1982 ENSG00000182903 "Zinc finger protein 721" Q8TF20 4 425815-499156 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 232.7;Loop of henle epithelial cells: 179.3;Podocytes: 205.2;Proximal tubule cells: 204.0;Renal collecting duct intercalated cells: 200.8;Renal collecting duct principal cells: 162.6;Renal connecting tubule cells: 186.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065313 Approved "Centriolar satellite,Cytosol" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 105: Non-specific - Mixed function" 1 Cytosol "Centriolar satellite" "HPA065313: " "unprognostic (1.17e-1)" "unprognostic (1.52e-1)" "unprognostic (2.05e-1)" "unprognostic (9.52e-2)" "unprognostic (1.14e-1)" "unprognostic (1.80e-1)" "unprognostic (4.06e-1)" "unprognostic (2.54e-2)" "unprognostic (1.20e-1)" "unprognostic (1.82e-2)" "unprognostic (4.50e-3)" "potential prognostic favorable (1.64e-4)" "unprognostic (3.18e-1)" "unprognostic (3.08e-1)" "unprognostic (3.30e-1)" "unprognostic (2.63e-1)" "unprognostic (5.20e-3)" "unprognostic (3.45e-1)" "unprognostic (1.21e-1)" "unprognostic (7.16e-2)" "unprognostic (3.80e-1)" "unprognostic (1.26e-1)" "unprognostic (9.07e-3)" "unprognostic (2.60e-2)" "unprognostic (8.40e-2)" "unprognostic (9.28e-2)" "unprognostic (2.08e-2)" "unprognostic (4.96e-2)" "unprognostic (5.47e-1)" "potential prognostic unfavorable (9.90e-4)" "unprognostic (1.67e-1)" ZNF722 ZNF722P ENSG00000241149 "Zinc finger protein 722" A0A1W2PQL4 7 63998849-64018081 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Tissue enriched" "Detected in single" 10 "testis: 1.6" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 17.0;Early primary spermatocytes: 8.1;Early spermatids: 5.6;Epicardial cells: 2.3;Late primary spermatocytes: 10.3;Undifferentiated spermatogonia: 4.1" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 20 "Testicular Germ Cell Tumor (TCGA): 2.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Spermatocytes" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 6: Non-specific - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 106: Spermatogonia - Spermatogonial differentiation" "unprognostic (8.51e-2)" ZNF723 ZNF723P ENSG00000268696 "Zinc finger protein 723" P0DPD5 19 22832291-22858667 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 9 "testis: 3.1" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 12.4;Early primary spermatocytes: 31.3;Early spermatids: 58.8;Late primary spermatocytes: 18.0;Oocytes: 4.6" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Testicular Germ Cell Tumor (TCGA): 12.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 57: Testis - Spermatogenesis" "Cluster 4: Non-specific - Transcription" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" "potential prognostic favorable (8.50e-4)" "unprognostic (2.45e-3)" "unprognostic (1.36e-1)" ZNF724 ZNF724P ENSG00000196081 "Zinc finger protein 724" A8MTY0 19 23221599-23250394 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 2.6;esophagus: 2.4" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 9.2;Early primary spermatocytes: 10.0;Erythrocyte progenitors: 11.6;Extravillous trophoblasts: 4.9;Megakaryocyte progenitors: 7.9;Megakaryocytes: 12.4;Oocytes: 9.2" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach)" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 27: Non-specific - Cell proliferation" 1 "unprognostic (1.80e-1)" "unprognostic (1.80e-1)" "potential prognostic unfavorable (8.39e-4)" "unprognostic (7.67e-2)" "unprognostic (8.23e-2)" "unprognostic (1.69e-1)" "unprognostic (4.12e-2)" "unprognostic (2.82e-2)" "unprognostic (3.24e-3)" "potential prognostic unfavorable (3.80e-5)" "unprognostic (1.45e-2)" "unprognostic (1.25e-1)" "unprognostic (1.85e-2)" "unprognostic (3.75e-2)" "unprognostic (1.07e-2)" "unprognostic (1.55e-1)" "unprognostic (1.00e-1)" "unprognostic (6.29e-3)" "unprognostic (2.91e-1)" "unprognostic (4.44e-3)" "unprognostic (2.09e-2)" "unprognostic (6.86e-2)" "unprognostic (6.18e-3)" "unprognostic (3.83e-1)" "unprognostic (3.91e-2)" ZNF726 ZNF92P3 ENSG00000213967 "Zinc finger protein 726" A6NNF4 19 23914876-23945159 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 27.8;Extravillous trophoblasts: 21.3;Migrating cytotrophoblasts: 16.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 7.8;NK-cell: 3.3" "Group enriched" "Detected in many" 5 "granulocytes: 7.8;NK-cells: 3.3" "Low cancer specificity" "Detected in many" "Skin - Sebaceous gland cells" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" 1 "potential prognostic favorable (5.30e-5)" "unprognostic (2.08e-1)" "unprognostic (1.25e-1)" "unprognostic (2.46e-2)" "unprognostic (3.91e-3)" "unprognostic (8.91e-2)" "unprognostic (1.75e-2)" "unprognostic (7.43e-2)" "unprognostic (6.42e-2)" "unprognostic (1.14e-1)" "unprognostic (1.37e-1)" "unprognostic (3.15e-2)" "unprognostic (3.25e-3)" "unprognostic (8.69e-3)" "unprognostic (4.99e-2)" "unprognostic (8.28e-2)" "unprognostic (6.95e-2)" "unprognostic (6.22e-2)" "unprognostic (2.20e-2)" "unprognostic (9.34e-2)" "unprognostic (2.17e-1)" "unprognostic (7.60e-2)" "unprognostic (1.10e-2)" "unprognostic (1.46e-1)" "unprognostic (1.26e-1)" "potential prognostic unfavorable (8.36e-4)" "unprognostic (2.18e-1)" "unprognostic (4.86e-1)" "unprognostic (5.05e-1)" "unprognostic (5.81e-2)" ZNF727 ZNF727P ENSG00000214652 "Zinc finger protein 727" A8MUV8 7 64045434-64085339 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Distal convoluted tubule cells: 11.9;Loop of henle epithelial cells: 12.9;Papillary tip epithelial cells: 12.8;Podocytes: 28.6;Proximal tubule cells: 9.9;Renal collecting duct intercalated cells: 9.0;Renal collecting duct principal cells: 17.8;Renal connecting tubule cells: 15.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 6.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 2.0" "HPA051027, HPA061215" Uncertain Uncertain Nucleoplasm NA NA "Cluster 65: Brain - Transcription" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 105: Non-specific - Mixed function" Nucleoplasm "HPA051027: , HPA061215: " "unprognostic (2.73e-2)" "unprognostic (2.20e-1)" "unprognostic (2.73e-3)" "unprognostic (1.72e-2)" "unprognostic (6.51e-3)" "unprognostic (1.13e-2)" "unprognostic (3.12e-3)" "unprognostic (3.67e-2)" "unprognostic (6.56e-2)" "unprognostic (9.37e-2)" "unprognostic (2.28e-1)" "unprognostic (2.17e-1)" "unprognostic (7.65e-2)" ZNF728 ENSG00000269067 "Zinc finger protein 728" P0DKX0 19 22974883-23003176 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "testis: 9.7" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 41.2;Differentiating spermatogonia: 10.6;Early primary spermatocytes: 13.8;Early spermatids: 11.4;Late primary spermatocytes: 20.1;Late spermatids: 11.7;Pituicytes/FSCs: 16.4;Renal collecting duct intercalated cells: 10.0;Renal collecting duct principal cells: 11.6;Sertoli cells: 10.6" "Cell type enhanced" "Detected in many" "fibroblast: 12.7;hippocampal CA4: 10.3" "Cancer enriched" "Detected in single" 10 "Testicular Germ Cell Tumor (TCGA): 9.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 1.4;testis cancer: 1.6" HPA077713 Approved "Nucleoli fibrillar center" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 19: Astrocytes - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" "Nucleoli fibrillar center" "HPA077713: " "unprognostic (2.00e-3)" "unprognostic (2.82e-1)" ZNF729 ENSG00000196350 "Zinc finger protein 729" A6NN14 19 22286441-22317176 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 16 "testis: 1.8" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 7.4;Early primary spermatocytes: 6.9;Early spermatids: 1.2;Late primary spermatocytes: 3.2;Late spermatids: 1.7;Undifferentiated spermatogonia: 2.9" "Cell type enhanced" "Detected in single" "hippocampal CA4: 2.6" "Cancer enriched" "Detected in single" 76 "Testicular Germ Cell Tumor (TCGA): 14.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "testis cancer: 1.2" "Testis - Spermatocytes" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 4: Non-specific - Transcription" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 1 "unprognostic (1.95e-1)" ZNF730 ENSG00000183850 "Zinc finger protein 730" Q6ZMV8 19 23075210-23147221 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 4.7" "Cell type enhanced" "Detected in many" "Early spermatids: 65.7;Late spermatids: 36.5;Megakaryocyte progenitors: 53.5;Oligodendrocyte progenitor cells: 32.3;Syncytiotrophoblasts: 29.1" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 7.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" NA NA "Cluster 61: Non-specific - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" "unprognostic (1.59e-1)" "unprognostic (2.11e-2)" "unprognostic (9.34e-3)" "unprognostic (2.23e-2)" "unprognostic (3.07e-2)" "unprognostic (1.15e-1)" "unprognostic (1.15e-1)" "unprognostic (2.03e-3)" "unprognostic (2.54e-1)" "unprognostic (4.74e-2)" "unprognostic (7.27e-2)" "unprognostic (4.67e-1)" "potential prognostic unfavorable (5.02e-5)" ZNF732 FLJ59067 ENSG00000186777 "Zinc finger protein 732" B4DXR9 4 270675-305474 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Adipocytes: 6.8;Brain inhibitory neurons: 8.1;Cardiomyocytes: 11.1;Differentiating spermatogonia: 23.5;Early primary spermatocytes: 27.7;Epicardial cells: 6.8;Oocytes: 9.2;Undifferentiated spermatogonia: 8.2" "Cell type enhanced" "Detected in many" "medium spiny neuron: 18.5" "Cancer enriched" "Detected in single" 6 "Testicular Germ Cell Tumor (TCGA): 5.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Adrenocortical cancer: 5.9" "Colon - Enteric glia cells" NA NA "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 1 "unprognostic (3.56e-2)" "unprognostic (8.00e-2)" "unprognostic (2.25e-1)" ZNF735 ZNF735P ENSG00000223614 "Zinc finger protein 735" P0CB33 7 64207203-64220290 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Early spermatids: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 5: Rhabdoid - Unknown function" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" ZNF736 ENSG00000234444 "Zinc finger protein 736" B4DX44 7 64307459-64356634 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 11.4" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 124.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "HPA051027, HPA061215" Uncertain Uncertain Nucleoplasm NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 9: Non-specific - Receptor signaling" "Cluster 4: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" Nucleoplasm "HPA051027: , HPA061215: " "unprognostic (6.79e-3)" "unprognostic (1.26e-1)" "unprognostic (3.33e-2)" "unprognostic (2.18e-2)" "unprognostic (2.71e-1)" "unprognostic (1.99e-1)" "unprognostic (5.33e-2)" "unprognostic (8.04e-2)" "unprognostic (1.16e-1)" "unprognostic (5.78e-3)" "unprognostic (1.64e-1)" "unprognostic (3.96e-1)" "unprognostic (2.07e-1)" "unprognostic (2.92e-2)" "unprognostic (2.20e-1)" "unprognostic (1.10e-1)" "unprognostic (2.09e-2)" "unprognostic (6.18e-2)" "unprognostic (5.63e-2)" "potential prognostic unfavorable (1.69e-4)" "potential prognostic unfavorable (4.72e-4)" "unprognostic (2.63e-2)" "unprognostic (2.71e-1)" "unprognostic (4.30e-2)" "unprognostic (7.38e-2)" "unprognostic (2.10e-1)" "potential prognostic unfavorable (4.19e-4)" "unprognostic (1.05e-1)" ZNF737 ZNF102 ENSG00000237440 "Zinc finger protein 737" O75373 19 20535825-20565809 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 35.6" "Cell type enhanced" "Detected in many" "Corticotrophs: 61.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 61: Non-specific - Transcription" "Cluster 33: Neurons - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" "unprognostic (7.38e-3)" "unprognostic (3.07e-2)" "unprognostic (1.00e-1)" "unprognostic (1.27e-1)" "unprognostic (4.14e-2)" "unprognostic (3.55e-2)" "unprognostic (4.23e-2)" "unprognostic (1.84e-3)" "unprognostic (3.04e-3)" "potential prognostic unfavorable (5.12e-4)" "potential prognostic favorable (6.13e-5)" "unprognostic (4.67e-2)" "unprognostic (2.59e-3)" "unprognostic (1.89e-2)" "potential prognostic favorable (4.22e-4)" "unprognostic (1.21e-1)" "unprognostic (2.97e-2)" "unprognostic (4.76e-1)" "unprognostic (1.24e-3)" "potential prognostic unfavorable (1.69e-4)" "unprognostic (1.79e-2)" "unprognostic (2.90e-1)" "unprognostic (3.25e-1)" "unprognostic (2.36e-3)" "unprognostic (2.73e-1)" "unprognostic (6.52e-2)" "unprognostic (3.30e-2)" "unprognostic (1.45e-1)" "unprognostic (1.05e-1)" "unprognostic (3.84e-1)" ZNF738 ENSG00000172687 "Zinc finger protein 738" Q8NE65 19 21358930-21388582 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells" HPA059135 Uncertain NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 4 "HPA059135: " "unprognostic (1.24e-3)" "unprognostic (2.12e-2)" "unprognostic (7.78e-2)" "unprognostic (1.93e-1)" "unprognostic (3.24e-1)" "unprognostic (6.07e-2)" "unprognostic (4.22e-2)" "unprognostic (4.40e-3)" "unprognostic (3.27e-1)" "unprognostic (3.57e-3)" "unprognostic (2.67e-3)" "unprognostic (9.31e-2)" "unprognostic (4.41e-1)" "unprognostic (8.35e-3)" "unprognostic (2.64e-2)" "unprognostic (1.02e-2)" "unprognostic (6.57e-2)" "unprognostic (1.02e-1)" "unprognostic (2.76e-3)" "unprognostic (4.22e-2)" "unprognostic (2.70e-1)" "potential prognostic unfavorable (2.86e-4)" "unprognostic (4.07e-2)" "unprognostic (4.36e-2)" "unprognostic (2.11e-2)" "unprognostic (1.48e-3)" "unprognostic (3.92e-2)" "unprognostic (2.64e-1)" "unprognostic (2.17e-1)" "unprognostic (1.51e-1)" ZNF74 "Cos52, Zfp520, ZNF520" ENSG00000185252 "Zinc finger protein 74" Q16587 22 20394115-20408461 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Somatotrophs: 15.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003354 Approved Supported "Nucleoplasm,Actin filaments" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 64: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 66: Non-specific - Mitochondria" "Cluster 109: Neurons - Neuronal signaling" 9 Nucleoplasm "Actin filaments" "HPA003354: " "unprognostic (1.31e-1)" "unprognostic (1.29e-1)" "unprognostic (1.86e-1)" "unprognostic (9.04e-2)" "unprognostic (1.51e-1)" "unprognostic (4.01e-1)" "unprognostic (8.74e-2)" "unprognostic (7.08e-3)" "unprognostic (1.56e-1)" "unprognostic (7.25e-2)" "unprognostic (2.04e-3)" "unprognostic (1.43e-2)" "unprognostic (3.51e-1)" "unprognostic (4.82e-2)" "unprognostic (1.37e-2)" "unprognostic (2.94e-1)" "unprognostic (4.09e-2)" "unprognostic (1.04e-1)" "unprognostic (1.97e-3)" "unprognostic (7.59e-2)" "unprognostic (2.87e-1)" "unprognostic (2.62e-1)" "unprognostic (1.62e-1)" "unprognostic (3.74e-1)" "potential prognostic favorable (9.43e-7)" "unprognostic (1.59e-1)" "unprognostic (1.29e-1)" "unprognostic (7.13e-2)" "unprognostic (3.34e-1)" "unprognostic (9.01e-2)" "unprognostic (2.97e-3)" ZNF740 Zfp740 ENSG00000139651 "Zinc finger protein 740" Q8NDX6 12 53180704-53195142 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Adipocytes: 330.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035691 Approved Approved Nucleoplasm NA NA "Cluster 41: Basophils - Unknown function" "Cluster 49: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 89: Adipocytes - Lipid metabolism" 1 Nucleoplasm "HPA035691: " "unprognostic (4.51e-2)" "unprognostic (1.58e-1)" "unprognostic (2.31e-1)" "unprognostic (1.69e-1)" "unprognostic (1.71e-1)" "unprognostic (3.11e-1)" "unprognostic (1.68e-1)" "unprognostic (8.86e-3)" "unprognostic (1.29e-2)" "unprognostic (5.91e-2)" "potential prognostic favorable (4.10e-4)" "unprognostic (6.10e-3)" "unprognostic (6.84e-2)" "unprognostic (5.37e-3)" "unprognostic (3.47e-2)" "unprognostic (1.31e-1)" "unprognostic (1.20e-1)" "unprognostic (2.00e-2)" "unprognostic (5.65e-3)" "unprognostic (8.76e-2)" "unprognostic (1.57e-3)" "unprognostic (8.71e-3)" "unprognostic (8.42e-3)" "unprognostic (7.37e-2)" "unprognostic (3.54e-2)" "unprognostic (1.55e-1)" "unprognostic (3.60e-2)" "unprognostic (1.43e-1)" "unprognostic (1.35e-1)" "unprognostic (1.05e-1)" "unprognostic (3.75e-2)" ZNF746 "FLJ31413, PARIS" ENSG00000181220 "Zinc finger protein 746" Q6NUN9 7 149472696-149497817 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Neutrophils: 109.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 7.0" "Lineage enriched" "Detected in many" 6 "granulocytes: 7.0" "Low cancer specificity" "Detected in all" "Spleen - Neutrophils_2, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020272 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 67: Testis - Mixed function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 24: Neutrophils - Innate immunity signal integration" 14 "Nucleoplasm, Cytosol" "HPA020272: " "unprognostic (2.37e-1)" "unprognostic (6.71e-2)" "unprognostic (2.66e-1)" "unprognostic (5.76e-2)" "unprognostic (5.33e-2)" "unprognostic (1.63e-1)" "unprognostic (5.56e-2)" "unprognostic (8.60e-2)" "unprognostic (1.48e-1)" "unprognostic (3.07e-1)" "unprognostic (3.27e-1)" "unprognostic (2.18e-2)" "unprognostic (3.28e-3)" "potential prognostic unfavorable (2.75e-6)" "unprognostic (1.23e-1)" "unprognostic (2.66e-2)" "potential prognostic unfavorable (1.00e-4)" "unprognostic (3.08e-1)" "unprognostic (5.77e-2)" "unprognostic (1.39e-1)" "unprognostic (2.60e-1)" "unprognostic (2.92e-3)" "unprognostic (1.93e-1)" "unprognostic (5.91e-2)" "unprognostic (8.38e-2)" "unprognostic (1.60e-1)" "unprognostic (2.77e-1)" "unprognostic (9.57e-2)" "unprognostic (9.15e-2)" "unprognostic (8.06e-2)" "unprognostic (6.96e-2)" ZNF747 MGC2474 ENSG00000169955 "Zinc finger protein 747" Q9BV97 16 30530367-30535347 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in some" 5 "Cardiomyocytes: 26.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA003203, HPA069173" Uncertain Approved Centrosome,Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 54: Non-specific - Transcription" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 22 "Centrosome, Cytosol" "HPA003203: , HPA069173: " "unprognostic (1.95e-2)" "unprognostic (4.29e-2)" "unprognostic (1.23e-1)" "unprognostic (4.60e-2)" "unprognostic (2.17e-2)" "unprognostic (1.77e-1)" "unprognostic (1.02e-1)" "unprognostic (1.17e-3)" "unprognostic (1.02e-2)" "unprognostic (3.94e-1)" "potential prognostic favorable (8.64e-6)" "unprognostic (8.16e-2)" "unprognostic (8.33e-2)" "unprognostic (1.03e-1)" "unprognostic (2.73e-3)" "unprognostic (7.08e-2)" "unprognostic (2.16e-2)" "unprognostic (2.66e-2)" "unprognostic (1.05e-2)" "unprognostic (4.09e-2)" "unprognostic (2.28e-1)" "potential prognostic favorable (2.53e-4)" "unprognostic (1.36e-1)" "unprognostic (3.09e-1)" "unprognostic (1.35e-1)" "unprognostic (1.30e-1)" "unprognostic (1.46e-1)" "unprognostic (2.28e-1)" "unprognostic (1.83e-1)" "unprognostic (1.26e-2)" "unprognostic (5.10e-3)" ZNF749 FLJ16360 ENSG00000186230 "Zinc finger protein 749" O43361 19 57435325-57447101 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Melanocytes: 25.6;Myonuclei: 48.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "HPA042082, HPA042091, HPA056001" Uncertain Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 18: Non-specific - Translation" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 55: Myocytes - Oxidative muscle function" 1 "Nucleoplasm, Nuclear membrane" "HPA042082: , HPA042091: , HPA056001: " "unprognostic (1.63e-2)" "unprognostic (3.17e-1)" "unprognostic (2.06e-1)" "unprognostic (1.19e-1)" "unprognostic (8.70e-2)" "unprognostic (2.17e-1)" "unprognostic (1.22e-1)" "unprognostic (2.88e-1)" "unprognostic (7.22e-3)" "unprognostic (1.81e-1)" "unprognostic (1.70e-2)" "unprognostic (6.53e-2)" "unprognostic (2.56e-1)" "unprognostic (3.84e-2)" "unprognostic (6.28e-2)" "unprognostic (6.21e-2)" "unprognostic (1.12e-1)" "unprognostic (4.68e-2)" "unprognostic (1.92e-1)" "unprognostic (1.09e-1)" "unprognostic (3.43e-1)" "unprognostic (1.17e-1)" "unprognostic (3.10e-2)" "unprognostic (2.47e-3)" "unprognostic (1.77e-3)" "unprognostic (3.28e-1)" "unprognostic (8.35e-2)" "unprognostic (2.58e-1)" "unprognostic (2.49e-2)" "unprognostic (2.78e-1)" ZNF750 "FLJ13841, Zfp750" ENSG00000141579 "Zinc finger protein 750" Q32MQ0 17 82829434-82840022 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Transcription, Transcription regulation" Activator "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 93.4;skin 1: 135.0;vagina: 50.6" "Cell type enhanced" "Detected in many" "Epicardial cells: 86.4;Esophageal apical cells: 412.3;Esophageal basal cells: 116.1;Esophageal suprabasal cells: 270.1;Ocular epithelial cells: 281.3;Prostatic hillock cells: 101.6;Suprabasal keratinocytes: 187.8;Syncytiotrophoblasts: 81.1;Urothelial cells: 171.5" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 44.9;Head and Neck Squamous Cell Carcinoma (TCGA): 43.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 15.5" "Lung - Alveolar cells type 2, Skin - Keratinocyte (other)" "Not detected" "Not detected" "HPA021573, HPA023012" Enhanced NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 6: Non-specific - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 7 "HPA021573: , HPA023012: " "unprognostic (3.18e-2)" "potential prognostic unfavorable (1.36e-4)" "unprognostic (1.14e-1)" "unprognostic (1.40e-1)" "unprognostic (3.86e-1)" "unprognostic (1.55e-1)" "potential prognostic favorable (5.51e-4)" "unprognostic (1.95e-1)" "unprognostic (3.20e-1)" "unprognostic (8.45e-2)" "unprognostic (2.15e-2)" "unprognostic (3.22e-1)" "unprognostic (1.01e-1)" "unprognostic (3.50e-2)" "unprognostic (5.09e-2)" "unprognostic (1.88e-1)" "unprognostic (5.87e-2)" "unprognostic (1.30e-1)" "unprognostic (1.27e-1)" "unprognostic (1.07e-1)" ZNF75A FLJ31529 ENSG00000162086 "Zinc finger protein 75a" Q96N20 16 3305406-3318852 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 117.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" HPA001665 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 22: Epididymis - Mixed function" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 4: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 1 Nucleoplasm "Nucleoli fibrillar center" "HPA001665: " "unprognostic (4.97e-1)" "unprognostic (1.23e-1)" "unprognostic (2.02e-1)" "unprognostic (2.39e-2)" "unprognostic (1.61e-1)" "unprognostic (2.25e-2)" "unprognostic (2.41e-1)" "unprognostic (6.23e-2)" "unprognostic (7.00e-3)" "unprognostic (1.48e-1)" "unprognostic (2.46e-3)" "potential prognostic favorable (3.48e-4)" "unprognostic (1.92e-3)" "unprognostic (1.85e-1)" "unprognostic (1.68e-1)" "unprognostic (1.16e-1)" "unprognostic (1.83e-1)" "unprognostic (3.28e-1)" "unprognostic (2.01e-1)" "unprognostic (6.09e-2)" "unprognostic (1.97e-1)" "unprognostic (2.51e-2)" "potential prognostic unfavorable (6.11e-4)" "unprognostic (1.56e-2)" "unprognostic (2.44e-1)" "unprognostic (7.21e-2)" "unprognostic (9.94e-3)" "unprognostic (1.22e-1)" "unprognostic (3.08e-1)" "unprognostic (1.59e-1)" "unprognostic (5.19e-2)" ZNF75D "D8C6, ZKSCAN24, ZNF75, ZNF82, ZSCAN28" ENSG00000186376 "Zinc finger protein 75D" P51815 X 135248920-135344109 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 127.6;Early spermatids: 198.6;Late spermatids: 475.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" HPA004705 Supported Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" "Nucleoplasm, Golgi apparatus" "HPA004705: " "unprognostic (2.07e-2)" "potential prognostic unfavorable (1.26e-5)" "unprognostic (8.49e-2)" "unprognostic (1.09e-1)" "unprognostic (8.13e-2)" "unprognostic (1.15e-1)" "unprognostic (2.51e-1)" "unprognostic (4.08e-3)" "unprognostic (8.50e-2)" "unprognostic (7.98e-2)" "unprognostic (1.72e-2)" "unprognostic (2.75e-3)" "unprognostic (1.56e-2)" "unprognostic (1.01e-1)" "unprognostic (3.97e-2)" "unprognostic (3.18e-3)" "unprognostic (6.00e-2)" "unprognostic (1.98e-2)" "unprognostic (2.43e-1)" "unprognostic (2.22e-1)" "unprognostic (2.22e-2)" "unprognostic (5.11e-3)" "unprognostic (1.98e-1)" "unprognostic (5.89e-2)" "unprognostic (1.12e-2)" "unprognostic (1.29e-2)" "unprognostic (1.08e-2)" "unprognostic (5.31e-2)" "unprognostic (1.23e-1)" "unprognostic (3.26e-2)" "unprognostic (1.08e-1)" ZNF76 "D6S229E, Zfp523, ZNF523" ENSG00000065029 "Zinc finger protein 76" P36508 6 35258909-35295985 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 135.5;Epicardial cells: 420.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030090, HPA030091" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 24: Non-specific - Transcription" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 28: Non-specific - Nuclear processes" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 67 Nucleoplasm Cytosol "HPA030090: , HPA030091: " "unprognostic (1.59e-1)" "unprognostic (6.13e-2)" "unprognostic (1.81e-2)" "unprognostic (5.65e-2)" "unprognostic (1.19e-1)" "unprognostic (3.06e-2)" "unprognostic (5.11e-2)" "unprognostic (1.39e-1)" "unprognostic (1.12e-1)" "unprognostic (4.32e-1)" "potential prognostic favorable (1.47e-4)" "unprognostic (6.85e-3)" "potential prognostic favorable (3.61e-6)" "unprognostic (2.23e-3)" "unprognostic (8.87e-2)" "unprognostic (2.98e-2)" "unprognostic (1.59e-1)" "unprognostic (3.31e-1)" "unprognostic (3.84e-1)" "unprognostic (1.40e-3)" "unprognostic (3.45e-1)" "potential prognostic favorable (6.08e-4)" "unprognostic (7.66e-2)" "unprognostic (3.24e-2)" "unprognostic (4.35e-3)" "potential prognostic favorable (8.22e-4)" "potential prognostic unfavorable (2.20e-4)" "unprognostic (3.41e-3)" "unprognostic (1.62e-1)" "unprognostic (1.27e-1)" "unprognostic (1.31e-1)" ZNF761 "FLJ16231, FLJ35333, KIAA2033" ENSG00000160336 "Zinc finger protein 761" Q86XN6 19 53431984-53461862 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "prostate: 69.3" "Cell type enhanced" "Detected in many" "Pancreatic islet cells: 46.8;Prostatic glandular cells: 74.8;Syncytiotrophoblasts: 69.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 87.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Prostate - Prostate glandular cells" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 4: Non-specific - Transcription" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 3 "unprognostic (2.18e-2)" "unprognostic (1.63e-2)" "unprognostic (3.70e-1)" "unprognostic (1.90e-3)" "unprognostic (2.17e-2)" "unprognostic (1.05e-1)" "unprognostic (3.17e-1)" "unprognostic (4.92e-1)" "unprognostic (2.71e-1)" "potential prognostic unfavorable (7.69e-4)" "unprognostic (1.36e-2)" "unprognostic (1.42e-1)" "unprognostic (2.04e-2)" "unprognostic (6.35e-3)" "unprognostic (1.30e-1)" "unprognostic (6.49e-2)" "unprognostic (5.41e-2)" "unprognostic (4.91e-2)" "unprognostic (4.23e-2)" "unprognostic (1.25e-1)" "unprognostic (4.13e-1)" "unprognostic (3.60e-3)" "unprognostic (5.66e-2)" "unprognostic (2.65e-1)" "unprognostic (7.07e-3)" "unprognostic (2.93e-1)" "unprognostic (6.93e-3)" "unprognostic (1.14e-1)" "unprognostic (2.78e-1)" "unprognostic (8.19e-2)" "unprognostic (1.22e-1)" ZNF763 ZNF440L ENSG00000197054 "Zinc finger protein 763" Q0D2J5 19 11965037-11980617 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 10.3;Late primary spermatocytes: 8.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" HPA047845 Approved Uncertain Nucleoplasm NA NA "Cluster 41: Basophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 4: Non-specific - Transcription" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 2 Nucleoplasm "HPA047845: " "unprognostic (2.63e-2)" "unprognostic (2.50e-1)" "unprognostic (1.03e-1)" "unprognostic (5.89e-2)" "unprognostic (3.90e-1)" "unprognostic (1.64e-1)" "unprognostic (8.10e-2)" "unprognostic (4.29e-2)" "unprognostic (1.55e-1)" "validated prognostic favorable (7.03e-4)" "validated prognostic favorable (2.90e-4)" "potential prognostic favorable (6.43e-4)" "unprognostic (2.82e-1)" "potential prognostic favorable (3.06e-4)" "unprognostic (1.38e-3)" "unprognostic (1.37e-1)" "unprognostic (2.46e-2)" "unprognostic (3.33e-2)" "unprognostic (8.11e-2)" "unprognostic (1.11e-1)" "unprognostic (1.35e-2)" "unprognostic (3.47e-1)" "unprognostic (1.98e-2)" "unprognostic (1.69e-1)" "unprognostic (2.94e-2)" "unprognostic (6.28e-3)" "unprognostic (1.55e-1)" "unprognostic (2.52e-1)" "unprognostic (1.75e-1)" "unprognostic (1.43e-1)" ZNF764 MGC13138 ENSG00000169951 "Zinc finger protein 764" Q96H86 16 30553764-30558374 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Tuft cells: 23.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" HPA003203 Uncertain Approved Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 24: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 54: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 48 Cytosol "HPA003203: " "unprognostic (2.47e-1)" "unprognostic (2.97e-2)" "unprognostic (3.72e-1)" "unprognostic (9.30e-2)" "unprognostic (1.83e-1)" "unprognostic (1.32e-1)" "unprognostic (5.59e-2)" "unprognostic (4.68e-3)" "unprognostic (1.57e-2)" "unprognostic (3.77e-1)" "potential prognostic favorable (2.69e-5)" "unprognostic (5.34e-2)" "unprognostic (1.19e-1)" "unprognostic (1.34e-3)" "unprognostic (1.08e-2)" "unprognostic (1.78e-2)" "unprognostic (4.56e-2)" "unprognostic (1.45e-1)" "unprognostic (3.54e-2)" "unprognostic (2.70e-1)" "unprognostic (1.83e-1)" "unprognostic (1.49e-2)" "unprognostic (1.10e-1)" "unprognostic (1.57e-2)" "unprognostic (1.21e-1)" "unprognostic (9.25e-2)" "unprognostic (2.03e-1)" "unprognostic (2.83e-1)" "unprognostic (1.62e-1)" "unprognostic (5.21e-3)" "unprognostic (6.99e-3)" ZNF765 ENSG00000196417 "Zinc finger protein 765" Q7L2R6 19 53389793-53430413 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 71.6;Leydig cells: 79.3;Sertoli cells: 69.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 4: Non-specific - Transcription" "Cluster 94: Gonadal somatic cells - Mixed function" 6 "unprognostic (1.33e-2)" "potential prognostic unfavorable (7.07e-4)" "unprognostic (2.51e-2)" "unprognostic (2.24e-3)" "unprognostic (8.72e-2)" "unprognostic (7.54e-2)" "unprognostic (2.54e-1)" "unprognostic (3.68e-1)" "unprognostic (1.32e-1)" "unprognostic (3.66e-2)" "unprognostic (1.23e-3)" "unprognostic (1.25e-2)" "unprognostic (3.42e-1)" "potential prognostic unfavorable (7.12e-5)" "unprognostic (1.25e-1)" "unprognostic (7.07e-2)" "unprognostic (4.71e-1)" "unprognostic (1.96e-2)" "unprognostic (4.17e-1)" "unprognostic (3.95e-1)" "unprognostic (2.06e-1)" "unprognostic (2.28e-1)" "unprognostic (2.81e-3)" "unprognostic (8.14e-2)" "unprognostic (1.16e-2)" "unprognostic (2.44e-1)" "unprognostic (1.29e-2)" "unprognostic (9.54e-2)" "unprognostic (1.75e-1)" "unprognostic (2.37e-2)" "unprognostic (3.43e-2)" ZNF766 ENSG00000196214 "Zinc finger protein 766" Q5HY98 19 52269587-52296046 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 89.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "HPA044882, HPA063496" Uncertain Supported Centrosome NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 39: Testis - Nuclear processes" "Cluster 6: Non-specific - Immune response" "Cluster 4: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 5 Centrosome "HPA044882: , HPA063496: " "unprognostic (3.95e-3)" "unprognostic (1.01e-1)" "unprognostic (6.05e-2)" "unprognostic (6.62e-2)" "unprognostic (2.87e-1)" "unprognostic (2.66e-1)" "unprognostic (9.07e-2)" "unprognostic (2.93e-1)" "unprognostic (4.49e-3)" "unprognostic (3.21e-2)" "unprognostic (1.82e-3)" "unprognostic (8.29e-3)" "unprognostic (2.89e-1)" "unprognostic (5.87e-2)" "unprognostic (1.70e-1)" "unprognostic (1.33e-1)" "unprognostic (4.00e-2)" "unprognostic (8.51e-2)" "unprognostic (2.12e-1)" "unprognostic (7.24e-2)" "unprognostic (2.60e-1)" "unprognostic (1.41e-2)" "unprognostic (1.84e-1)" "unprognostic (1.73e-2)" "unprognostic (1.15e-3)" "unprognostic (2.58e-1)" "unprognostic (4.07e-2)" "unprognostic (2.10e-1)" "unprognostic (4.88e-2)" "unprognostic (1.55e-1)" "unprognostic (9.50e-2)" ZNF768 FLJ23436 ENSG00000169957 "Zinc finger protein 768" Q9H5H4 16 30524004-30526821 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 47.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024630, HPA066512" Supported Approved Nucleoplasm,Vesicles NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 19: Astrocytes - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 41 Nucleoplasm Vesicles "HPA024630: , HPA066512: " "unprognostic (1.20e-1)" "unprognostic (1.05e-1)" "unprognostic (6.06e-2)" "unprognostic (3.05e-3)" "unprognostic (7.01e-2)" "unprognostic (1.14e-1)" "unprognostic (1.90e-1)" "potential prognostic favorable (1.84e-4)" "unprognostic (1.35e-1)" "unprognostic (2.93e-1)" "potential prognostic favorable (5.92e-4)" "unprognostic (1.59e-2)" "unprognostic (1.51e-1)" "potential prognostic unfavorable (6.01e-4)" "unprognostic (1.29e-3)" "unprognostic (9.97e-2)" "unprognostic (5.93e-2)" "unprognostic (2.23e-1)" "unprognostic (3.36e-2)" "unprognostic (9.25e-2)" "unprognostic (8.86e-2)" "unprognostic (9.92e-2)" "unprognostic (4.27e-1)" "unprognostic (3.06e-2)" "unprognostic (2.64e-2)" "unprognostic (8.07e-2)" "unprognostic (1.59e-1)" "unprognostic (1.87e-1)" "unprognostic (1.38e-1)" "unprognostic (1.70e-2)" "unprognostic (1.33e-1)" ZNF77 pT1 ENSG00000175691 "Zinc finger protein 77" Q15935 19 2933218-2944971 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023397 Uncertain Approved Nucleoplasm,Nucleoli No No "Cluster 43: Non-specific - Transcription & Translation" "Cluster 64: Non-specific - Transcription" "Cluster 35: Non-specific - DNA binding" "Cluster 23: Non-specific - Transcription" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 10 "Nucleoplasm, Nucleoli" "HPA023397: " "unprognostic (5.33e-3)" "unprognostic (7.07e-2)" "unprognostic (2.69e-2)" "unprognostic (1.95e-1)" "unprognostic (2.01e-1)" "unprognostic (2.26e-1)" "unprognostic (5.47e-2)" "unprognostic (1.61e-2)" "unprognostic (1.05e-1)" "unprognostic (5.60e-2)" "unprognostic (5.59e-3)" "unprognostic (5.80e-2)" "unprognostic (8.97e-2)" "unprognostic (1.79e-2)" "unprognostic (1.38e-1)" "potential prognostic favorable (2.71e-4)" "unprognostic (2.22e-1)" "unprognostic (1.25e-2)" "potential prognostic favorable (1.98e-4)" "unprognostic (1.72e-1)" "unprognostic (1.88e-1)" "unprognostic (4.40e-3)" "unprognostic (4.56e-2)" "unprognostic (9.64e-3)" "unprognostic (1.83e-2)" "unprognostic (1.96e-2)" "unprognostic (4.07e-2)" "unprognostic (1.64e-1)" "unprognostic (9.50e-2)" "unprognostic (1.17e-1)" "unprognostic (7.19e-2)" ZNF770 "FLJ20582, PRO1914" ENSG00000198146 "Zinc finger protein 770" Q6IQ21 15 34978341-34988287 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 292.9;Esophageal suprabasal cells: 189.9;Neutrophil progenitors: 132.2;Suprabasal keratinocytes: 133.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024518, HPA053096" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 22: Epididymis - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 25 Nucleoplasm Cytosol "HPA024518: , HPA053096: " "unprognostic (2.11e-1)" "unprognostic (4.93e-2)" "unprognostic (5.36e-2)" "unprognostic (1.38e-1)" "unprognostic (1.34e-1)" "unprognostic (1.81e-1)" "unprognostic (5.03e-2)" "unprognostic (7.84e-3)" "unprognostic (7.29e-2)" "unprognostic (2.69e-2)" "validated prognostic favorable (1.58e-7)" "validated prognostic favorable (9.10e-5)" "unprognostic (3.17e-1)" "unprognostic (2.04e-1)" "unprognostic (1.75e-1)" "unprognostic (2.08e-2)" "unprognostic (2.32e-1)" "unprognostic (6.89e-2)" "unprognostic (6.94e-2)" "unprognostic (2.92e-1)" "potential prognostic unfavorable (1.75e-4)" "unprognostic (6.04e-3)" "unprognostic (2.79e-2)" "unprognostic (6.73e-2)" "unprognostic (5.98e-2)" "unprognostic (1.39e-1)" "unprognostic (5.28e-2)" "unprognostic (3.54e-1)" "unprognostic (2.50e-1)" "unprognostic (8.53e-2)" "unprognostic (1.70e-1)" ZNF771 DSC43 ENSG00000179965 "Zinc finger protein 771" Q7L3S4 16 30407414-30431108 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030730, HPA046672, HPA059398" Uncertain Enhanced Nucleoplasm,Nucleoli No No "Cluster 43: Non-specific - Transcription & Translation" "Cluster 78: Brain - Neuronal signaling" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 94: Gonadal somatic cells - Mixed function" 13 "Nucleoplasm, Nucleoli" "HPA030730: , HPA046672: , HPA059398: " "unprognostic (2.19e-2)" "unprognostic (4.28e-2)" "unprognostic (9.51e-2)" "unprognostic (4.35e-2)" "unprognostic (8.08e-3)" "unprognostic (2.57e-1)" "unprognostic (7.25e-2)" "potential prognostic favorable (1.65e-5)" "unprognostic (1.32e-1)" "unprognostic (6.67e-2)" "unprognostic (1.51e-1)" "unprognostic (1.14e-1)" "unprognostic (2.43e-1)" "unprognostic (1.24e-1)" "unprognostic (2.69e-1)" "unprognostic (6.66e-2)" "unprognostic (8.49e-2)" "unprognostic (1.56e-2)" "potential prognostic favorable (5.62e-4)" "unprognostic (3.58e-2)" "unprognostic (8.31e-2)" "potential prognostic favorable (3.28e-4)" "unprognostic (7.26e-2)" "unprognostic (2.91e-2)" "potential prognostic favorable (4.06e-4)" "unprognostic (2.59e-1)" "unprognostic (2.47e-2)" "unprognostic (1.00e-1)" "unprognostic (7.23e-2)" "unprognostic (4.77e-2)" "unprognostic (1.11e-2)" ZNF772 DKFZp686I1569 ENSG00000197128 "Zinc finger protein 772" Q68DY9 19 57466663-57477570 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" HPA031312 Uncertain Approved Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 2: Neurons - Nucleosome" "Cluster 4: Non-specific - Transcription" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 1 Cytosol "HPA031312: " "unprognostic (2.02e-1)" "unprognostic (4.32e-2)" "unprognostic (3.19e-1)" "unprognostic (2.61e-2)" "unprognostic (9.33e-2)" "unprognostic (1.75e-1)" "unprognostic (1.68e-1)" "unprognostic (2.94e-2)" "unprognostic (2.95e-1)" "validated prognostic favorable (3.17e-7)" "validated prognostic favorable (2.29e-4)" "unprognostic (1.43e-3)" "unprognostic (2.35e-1)" "unprognostic (1.68e-1)" "unprognostic (8.35e-2)" "unprognostic (3.57e-1)" "unprognostic (4.86e-2)" "unprognostic (4.42e-1)" "unprognostic (4.11e-1)" "unprognostic (9.55e-3)" "unprognostic (4.96e-2)" "unprognostic (3.82e-2)" "unprognostic (1.24e-1)" "unprognostic (5.26e-3)" "unprognostic (3.39e-2)" "unprognostic (2.07e-1)" "unprognostic (1.48e-1)" "unprognostic (1.69e-1)" ZNF773 "MGC4728, ZNF419B" ENSG00000152439 "Zinc finger protein 773" Q6PK81 19 57499915-57518404 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 6.0;Bergmann glia: 7.7;Brain excitatory neurons: 8.1;Brain inhibitory neurons: 7.4;Choroid plexus epithelial cells: 7.2;Distal convoluted tubule cells: 4.8;Ependymal cells: 5.4;Loop of henle epithelial cells: 3.6;Oligodendrocyte progenitor cells: 5.5;Oligodendrocytes: 3.5;Other brain neurons: 6.5;Podocytes: 5.7;Renal collecting duct intercalated cells: 4.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" HPA003152 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 102: Non-specific - Mixed function" 2 Nucleoplasm "Nucleoli fibrillar center" "HPA003152: " "unprognostic (4.64e-2)" "unprognostic (3.11e-1)" "unprognostic (2.60e-1)" "unprognostic (4.22e-2)" "unprognostic (1.06e-1)" "unprognostic (9.46e-3)" "unprognostic (8.18e-2)" "unprognostic (1.41e-1)" "unprognostic (1.43e-1)" "unprognostic (1.41e-1)" "validated prognostic favorable (2.58e-6)" "validated prognostic favorable (2.61e-5)" "unprognostic (1.79e-2)" "unprognostic (5.68e-2)" "unprognostic (1.56e-2)" "unprognostic (1.02e-1)" "unprognostic (4.87e-2)" "unprognostic (2.77e-1)" "unprognostic (8.56e-2)" "unprognostic (1.44e-1)" "unprognostic (2.97e-1)" "unprognostic (2.18e-3)" "unprognostic (9.19e-2)" "potential prognostic unfavorable (9.76e-5)" "unprognostic (1.38e-2)" "unprognostic (2.99e-1)" "unprognostic (2.71e-2)" "unprognostic (7.49e-2)" "unprognostic (4.88e-2)" "unprognostic (9.31e-2)" "unprognostic (1.88e-1)" ZNF774 MGC75360 ENSG00000196391 "Zinc finger protein 774" Q6NX45 15 90352284-90369146 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 23.3;Myonuclei: 42.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells" "HPA030839, HPA030840" Uncertain Supported "Intermediate filaments,Cytosol" No No "Cluster 20: Non-specific - DNA binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 15: Non-specific - Transcription" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 55: Myocytes - Oxidative muscle function" 68 "Intermediate filaments" Cytosol "HPA030839: , HPA030840: " "unprognostic (9.07e-3)" "unprognostic (1.33e-1)" "unprognostic (4.06e-1)" "unprognostic (3.18e-2)" "unprognostic (4.43e-1)" "unprognostic (3.76e-3)" "unprognostic (1.80e-1)" "unprognostic (2.68e-3)" "unprognostic (1.53e-1)" "potential prognostic unfavorable (2.11e-5)" "unprognostic (1.28e-1)" "potential prognostic favorable (9.58e-4)" "unprognostic (1.99e-1)" "unprognostic (4.02e-2)" "unprognostic (2.23e-1)" "unprognostic (3.01e-2)" "unprognostic (5.15e-3)" "unprognostic (2.09e-2)" "unprognostic (2.59e-1)" "unprognostic (1.63e-1)" "unprognostic (5.74e-1)" "unprognostic (1.27e-1)" "unprognostic (4.83e-3)" "unprognostic (2.11e-2)" "unprognostic (9.71e-3)" "unprognostic (2.01e-1)" "unprognostic (1.73e-1)" "unprognostic (4.09e-2)" ZNF775 MGC33584 ENSG00000196456 "Zinc finger protein 775" Q96BV0 7 150368790-150398630 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Gonadotrophs: 7.4;Thyrotrophs: 6.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts" "Low region specificity" "Detected in all" HPA073171 Approved NA NA "Cluster 64: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 39: Non-specific - Transcription" "Cluster 51: Secretory epithelial cells - Mixed function" 9 "HPA073171: " "unprognostic (1.26e-1)" "unprognostic (1.27e-1)" "unprognostic (6.24e-2)" "unprognostic (7.00e-2)" "unprognostic (1.12e-1)" "unprognostic (2.06e-1)" "unprognostic (1.62e-1)" "unprognostic (4.63e-2)" "unprognostic (1.37e-3)" "unprognostic (1.28e-2)" "unprognostic (8.35e-2)" "unprognostic (1.74e-1)" "unprognostic (1.59e-2)" "unprognostic (1.03e-2)" "unprognostic (8.22e-3)" "unprognostic (1.75e-1)" "unprognostic (1.80e-2)" "unprognostic (3.80e-2)" "unprognostic (1.54e-1)" "unprognostic (2.48e-1)" "unprognostic (1.75e-1)" "potential prognostic favorable (5.49e-6)" "unprognostic (2.45e-2)" "unprognostic (2.92e-1)" "unprognostic (7.50e-2)" "unprognostic (2.54e-2)" "unprognostic (8.66e-2)" "unprognostic (1.42e-3)" "unprognostic (5.44e-2)" "unprognostic (1.62e-2)" "unprognostic (4.98e-2)" ZNF776 FLJ38288 ENSG00000152443 "Zinc finger protein 776" Q68DI1 19 57746815-57758148 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA046653, HPA068553" Uncertain Approved Nucleoplasm,Cytosol No No "Cluster 41: Basophils - Unknown function" "Cluster 22: Epididymis - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 5 Nucleoplasm Cytosol "HPA046653: , HPA068553: " "unprognostic (1.45e-3)" "unprognostic (4.53e-2)" "unprognostic (1.22e-1)" "unprognostic (7.49e-2)" "unprognostic (2.29e-1)" "unprognostic (2.20e-1)" "unprognostic (3.63e-1)" "unprognostic (1.19e-1)" "unprognostic (1.16e-1)" "unprognostic (2.81e-1)" "potential prognostic favorable (7.05e-7)" "unprognostic (2.84e-3)" "unprognostic (6.33e-2)" "unprognostic (9.46e-2)" "unprognostic (2.65e-2)" "unprognostic (5.15e-2)" "unprognostic (1.65e-1)" "unprognostic (1.04e-1)" "unprognostic (1.75e-1)" "unprognostic (7.82e-2)" "unprognostic (2.18e-1)" "unprognostic (4.08e-2)" "unprognostic (1.43e-1)" "unprognostic (1.83e-2)" "unprognostic (3.42e-2)" "unprognostic (2.42e-1)" "unprognostic (6.00e-2)" "unprognostic (1.77e-2)" "unprognostic (1.89e-1)" "unprognostic (8.28e-2)" "unprognostic (2.03e-1)" ZNF777 KIAA1285 ENSG00000196453 "Zinc finger protein 777" Q9ULD5 7 149431363-149461062 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003252 Approved Approved Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 10 Nucleoplasm "HPA003252: " "unprognostic (1.26e-2)" "unprognostic (3.97e-1)" "unprognostic (1.69e-2)" "unprognostic (2.08e-2)" "unprognostic (1.11e-1)" "unprognostic (1.12e-2)" "unprognostic (2.65e-1)" "unprognostic (1.65e-1)" "unprognostic (1.27e-1)" "unprognostic (3.08e-1)" "unprognostic (1.48e-2)" "unprognostic (9.45e-2)" "unprognostic (1.42e-1)" "potential prognostic unfavorable (1.01e-4)" "unprognostic (8.91e-2)" "unprognostic (5.71e-3)" "unprognostic (6.32e-3)" "unprognostic (2.53e-1)" "unprognostic (2.15e-2)" "unprognostic (2.86e-1)" "unprognostic (3.25e-1)" "unprognostic (4.86e-3)" "unprognostic (2.01e-1)" "unprognostic (2.41e-1)" "unprognostic (3.39e-2)" "unprognostic (1.34e-1)" "unprognostic (9.42e-2)" "unprognostic (1.84e-1)" "unprognostic (2.70e-1)" "unprognostic (2.35e-2)" "unprognostic (5.28e-2)" ZNF778 FLJ31875 ENSG00000170100 "Zinc finger protein 778" Q96MU6 16 89217703-89237141 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Platelets: 320.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 10.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "HPA052057, HPA057151" Uncertain Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 61: Non-specific - Transcription" "Cluster 35: Non-specific - DNA binding" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 47: Platelets - Hemostasis" 1 "Nuclear bodies" Nucleoplasm "HPA052057: , HPA057151: " "unprognostic (1.10e-1)" "unprognostic (4.67e-2)" "unprognostic (2.00e-1)" "unprognostic (8.49e-2)" "unprognostic (2.39e-2)" "unprognostic (1.53e-2)" "unprognostic (1.71e-1)" "potential prognostic favorable (1.96e-5)" "unprognostic (7.71e-2)" "unprognostic (1.16e-1)" "potential prognostic favorable (1.06e-5)" "unprognostic (1.96e-3)" "potential prognostic favorable (3.51e-4)" "unprognostic (1.38e-1)" "unprognostic (6.84e-3)" "unprognostic (3.17e-1)" "unprognostic (8.16e-2)" "unprognostic (2.78e-1)" "unprognostic (1.27e-1)" "unprognostic (2.83e-2)" "potential prognostic favorable (1.81e-4)" "unprognostic (1.56e-2)" "unprognostic (1.23e-1)" "unprognostic (8.90e-3)" "unprognostic (1.17e-1)" "unprognostic (1.05e-1)" "unprognostic (8.52e-2)" "unprognostic (2.75e-1)" "unprognostic (1.45e-1)" "unprognostic (6.61e-2)" ZNF780A ZNF780 ENSG00000197782 "Zinc finger protein 780A" O75290 19 40069152-40090943 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 26.7;Hepatocytes: 25.4;Kupffer cells: 18.4;Microglia: 16.7;Podocytes: 15.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA003311 Uncertain Approved Nucleoplasm,Centrosome NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 102: Non-specific - Mixed function" 4 Nucleoplasm Centrosome "HPA003311: " "unprognostic (4.80e-2)" "unprognostic (1.86e-2)" "unprognostic (9.36e-2)" "potential prognostic unfavorable (7.41e-5)" "unprognostic (2.60e-1)" "unprognostic (1.41e-1)" "unprognostic (9.41e-2)" "unprognostic (9.74e-2)" "unprognostic (3.98e-2)" "unprognostic (2.59e-2)" "potential prognostic favorable (5.16e-4)" "unprognostic (1.02e-2)" "unprognostic (5.21e-2)" "unprognostic (6.69e-2)" "unprognostic (2.75e-3)" "unprognostic (2.85e-2)" "unprognostic (1.67e-1)" "unprognostic (1.00e-2)" "unprognostic (4.44e-1)" "unprognostic (6.82e-3)" "unprognostic (1.34e-2)" "unprognostic (2.80e-2)" "unprognostic (2.75e-1)" "unprognostic (3.99e-1)" "unprognostic (9.87e-3)" "unprognostic (1.28e-1)" "potential prognostic unfavorable (3.64e-4)" "unprognostic (8.28e-2)" "unprognostic (2.96e-1)" "unprognostic (9.00e-2)" "unprognostic (4.58e-2)" ZNF780B ZNF779 ENSG00000128000 "Zinc finger protein 780B" Q9Y6R6 19 40028260-40056231 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 80.5;Bergmann glia: 73.6;Brain excitatory neurons: 79.0;Brain inhibitory neurons: 91.8;Choroid plexus epithelial cells: 121.8;Distal convoluted tubule cells: 138.1;Ependymal cells: 69.1;Loop of henle epithelial cells: 89.9;Microglia: 109.5;Oligodendrocyte progenitor cells: 83.0;Oligodendrocytes: 89.0;Other brain neurons: 61.5;Papillary tip epithelial cells: 57.4;Podocytes: 94.5;Proximal tubule cells: 117.4;Renal collecting duct intercalated cells: 80.4;Renal collecting duct principal cells: 67.2;Renal connecting tubule cells: 120.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" HPA003311 Uncertain Approved Nucleoplasm,Centrosome NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 64: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 102: Non-specific - Mixed function" Nucleoplasm Centrosome "HPA003311: " "unprognostic (3.31e-2)" "unprognostic (3.71e-1)" "unprognostic (5.29e-2)" "unprognostic (5.73e-2)" "unprognostic (8.79e-2)" "unprognostic (9.38e-2)" "unprognostic (3.19e-1)" "unprognostic (3.23e-2)" "potential prognostic favorable (2.52e-5)" "unprognostic (2.58e-3)" "unprognostic (1.55e-1)" "unprognostic (4.74e-2)" "unprognostic (8.93e-2)" "unprognostic (2.02e-1)" "unprognostic (1.01e-2)" "potential prognostic unfavorable (2.42e-6)" "unprognostic (2.31e-2)" "unprognostic (2.82e-2)" "unprognostic (4.35e-3)" "unprognostic (1.80e-1)" "unprognostic (3.74e-3)" "unprognostic (8.63e-2)" "unprognostic (2.43e-1)" "unprognostic (1.19e-1)" "unprognostic (1.27e-1)" ZNF782 FLJ16636 ENSG00000196597 "Zinc finger protein 782" Q6ZMW2 9 96816269-96875623 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" HPA011013 Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 42: Retina - Visual perception" "Cluster 15: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 51: Secretory epithelial cells - Mixed function" "Nucleoplasm, Mitochondria" "HPA011013: " "unprognostic (7.22e-3)" "unprognostic (2.10e-3)" "unprognostic (2.92e-2)" "unprognostic (6.37e-2)" "unprognostic (1.70e-1)" "unprognostic (4.19e-1)" "unprognostic (5.95e-3)" "unprognostic (9.93e-3)" "unprognostic (7.44e-2)" "validated prognostic favorable (6.64e-5)" "validated prognostic favorable (5.45e-4)" "unprognostic (2.04e-1)" "unprognostic (3.70e-2)" "unprognostic (5.02e-2)" "unprognostic (6.90e-2)" "unprognostic (2.03e-1)" "unprognostic (7.48e-2)" "unprognostic (4.84e-2)" "unprognostic (4.11e-1)" "unprognostic (2.33e-1)" "unprognostic (1.25e-1)" "unprognostic (9.41e-2)" "unprognostic (2.01e-2)" "unprognostic (2.06e-2)" "unprognostic (2.89e-1)" "unprognostic (6.76e-2)" "unprognostic (2.26e-1)" "unprognostic (1.16e-2)" "unprognostic (9.75e-3)" ZNF783 DKFZp667J212 ENSG00000204946 "Zinc finger protein 783" Q6ZMS7 7 149262171-149297302 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" HPA020375 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 64: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 39: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 4 "Plasma membrane, Cytosol" "HPA020375: " "unprognostic (4.60e-2)" "unprognostic (7.12e-2)" "unprognostic (2.30e-1)" "unprognostic (4.26e-2)" "unprognostic (2.40e-2)" "unprognostic (1.14e-1)" "unprognostic (5.37e-1)" "unprognostic (3.84e-3)" "unprognostic (2.31e-1)" "potential prognostic unfavorable (2.91e-4)" "unprognostic (6.13e-3)" "unprognostic (2.44e-1)" "unprognostic (1.49e-2)" "unprognostic (9.59e-3)" "unprognostic (2.56e-1)" "unprognostic (5.84e-3)" "unprognostic (1.15e-1)" "unprognostic (2.72e-1)" "unprognostic (2.66e-2)" "unprognostic (6.10e-2)" "unprognostic (2.00e-1)" "unprognostic (1.63e-2)" "unprognostic (7.77e-2)" "unprognostic (6.43e-2)" "unprognostic (3.51e-3)" "unprognostic (9.38e-3)" "unprognostic (4.54e-2)" "unprognostic (3.17e-2)" "unprognostic (1.98e-2)" "unprognostic (1.90e-1)" ZNF784 MGC75238 ENSG00000179922 "Zinc finger protein 784" Q8NCA9 19 55620741-55624566 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 40.2" "Cell type enhanced" "Detected in many" "Myonuclei: 21.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059676 Uncertain Approved Nucleoplasm NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 11 Nucleoplasm "HPA059676: " "unprognostic (1.99e-3)" "unprognostic (1.74e-1)" "unprognostic (3.41e-2)" "unprognostic (1.77e-1)" "unprognostic (1.47e-2)" "unprognostic (3.73e-2)" "unprognostic (3.07e-1)" "unprognostic (7.40e-2)" "unprognostic (2.31e-2)" "unprognostic (2.01e-1)" "unprognostic (3.83e-3)" "unprognostic (1.78e-2)" "potential prognostic favorable (2.68e-4)" "unprognostic (1.76e-1)" "unprognostic (3.55e-2)" "unprognostic (6.84e-2)" "unprognostic (3.77e-1)" "unprognostic (2.30e-1)" "unprognostic (1.78e-1)" "unprognostic (3.11e-1)" "unprognostic (2.81e-1)" "unprognostic (6.26e-3)" "unprognostic (2.96e-1)" "unprognostic (1.88e-1)" "unprognostic (2.33e-2)" "unprognostic (2.45e-1)" "unprognostic (1.74e-2)" "unprognostic (3.23e-1)" "unprognostic (9.29e-2)" "unprognostic (1.59e-1)" "unprognostic (1.35e-1)" ZNF785 FLJ32130 ENSG00000197162 "Zinc finger protein 785" A8K8V0 16 30573740-30585769 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004010 Approved Cytosol NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 64: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 16 Cytosol "HPA004010: " "unprognostic (6.53e-3)" "unprognostic (4.00e-2)" "unprognostic (8.52e-2)" "unprognostic (1.00e-1)" "unprognostic (4.60e-2)" "unprognostic (2.52e-1)" "unprognostic (2.78e-1)" "unprognostic (1.26e-2)" "unprognostic (8.75e-3)" "unprognostic (7.18e-3)" "unprognostic (3.93e-1)" "unprognostic (7.11e-3)" "unprognostic (3.30e-1)" "potential prognostic unfavorable (5.75e-4)" "unprognostic (4.04e-2)" "unprognostic (8.58e-3)" "unprognostic (3.23e-1)" "unprognostic (2.74e-2)" "unprognostic (1.04e-3)" "unprognostic (1.35e-1)" "unprognostic (3.78e-1)" "potential prognostic favorable (6.96e-4)" "unprognostic (1.38e-2)" "unprognostic (5.90e-2)" "unprognostic (2.46e-2)" "unprognostic (2.25e-1)" "unprognostic (3.48e-2)" "unprognostic (5.73e-2)" "unprognostic (1.60e-1)" "unprognostic (9.46e-3)" "potential prognostic favorable (6.69e-4)" ZNF786 DKFZp762I137 ENSG00000197362 "Zinc finger protein 786" Q8N393 7 149069641-149090782 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021518, HPA053459" Uncertain Approved "Nucleoplasm,Nuclear speckles,Nuclear bodies" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 39: Non-specific - Transcription" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 10 "Nucleoplasm, Nuclear speckles" "Nuclear bodies" "HPA021518: , HPA053459: " "unprognostic (1.11e-1)" "unprognostic (2.80e-1)" "unprognostic (3.99e-1)" "unprognostic (1.35e-1)" "unprognostic (2.30e-1)" "unprognostic (7.77e-3)" "unprognostic (1.94e-1)" "unprognostic (1.77e-2)" "unprognostic (5.09e-2)" "unprognostic (4.36e-2)" "unprognostic (1.15e-1)" "unprognostic (2.36e-2)" "unprognostic (4.77e-1)" "potential prognostic unfavorable (5.92e-5)" "unprognostic (2.90e-1)" "unprognostic (1.52e-1)" "unprognostic (1.09e-1)" "unprognostic (3.27e-2)" "unprognostic (2.90e-3)" "unprognostic (1.19e-2)" "unprognostic (8.62e-2)" "unprognostic (2.05e-3)" "unprognostic (5.08e-2)" "unprognostic (1.04e-1)" "unprognostic (2.22e-1)" "unprognostic (4.43e-2)" "unprognostic (3.98e-3)" "unprognostic (1.65e-2)" "unprognostic (7.27e-2)" "unprognostic (9.65e-2)" "unprognostic (5.80e-2)" ZNF787 ENSG00000142409 "Zinc finger protein 787" Q6DD87 19 56087366-56121295 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 132.5;Endometrial ciliated cells: 104.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035140 Supported Approved Nucleoplasm,Nucleoli,Mitochondria NA NA "Cluster 41: Basophils - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 18: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 5 Nucleoplasm "Nucleoli, Mitochondria" "HPA035140: " "unprognostic (1.26e-1)" "unprognostic (4.29e-2)" "unprognostic (8.48e-3)" "unprognostic (1.84e-2)" "unprognostic (1.94e-1)" "unprognostic (2.83e-1)" "unprognostic (1.83e-1)" "unprognostic (3.41e-1)" "unprognostic (1.21e-1)" "unprognostic (6.20e-2)" "unprognostic (3.92e-2)" "unprognostic (1.40e-1)" "unprognostic (8.63e-2)" "unprognostic (2.73e-3)" "unprognostic (6.83e-2)" "unprognostic (4.97e-2)" "unprognostic (3.07e-2)" "unprognostic (2.99e-1)" "unprognostic (3.59e-1)" "unprognostic (1.67e-1)" "unprognostic (1.18e-1)" "unprognostic (8.04e-2)" "unprognostic (3.34e-1)" "unprognostic (6.49e-3)" "unprognostic (2.16e-1)" "unprognostic (1.19e-1)" "unprognostic (1.45e-1)" "unprognostic (6.62e-2)" "unprognostic (2.87e-2)" "unprognostic (2.57e-2)" "unprognostic (2.01e-1)" ZNF789 ENSG00000198556 "Zinc finger protein 789" Q5FWF6 7 99472890-99503650 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 132.0;Epicardial cells: 116.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Skeletal muscle - Fibroblasts, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "HPA029500, HPA050793" Uncertain Enhanced Nucleoplasm NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 64: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 39: Non-specific - Transcription" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 1 Nucleoplasm "HPA029500: , HPA050793: " "unprognostic (3.87e-2)" "unprognostic (9.57e-2)" "unprognostic (4.20e-2)" "unprognostic (3.18e-1)" "unprognostic (6.16e-3)" "unprognostic (3.84e-1)" "unprognostic (1.29e-1)" "unprognostic (2.60e-1)" "unprognostic (2.45e-1)" "unprognostic (2.82e-3)" "unprognostic (2.26e-3)" "unprognostic (1.46e-1)" "unprognostic (1.40e-1)" "potential prognostic unfavorable (1.55e-5)" "unprognostic (1.35e-2)" "unprognostic (1.24e-1)" "unprognostic (2.35e-2)" "unprognostic (3.89e-3)" "unprognostic (3.02e-2)" "unprognostic (5.41e-2)" "unprognostic (1.10e-2)" "potential prognostic favorable (1.95e-4)" "unprognostic (3.53e-2)" "unprognostic (8.82e-2)" "unprognostic (1.33e-1)" "unprognostic (3.86e-1)" "unprognostic (1.09e-1)" "unprognostic (5.77e-2)" "unprognostic (1.64e-1)" "unprognostic (1.23e-1)" "unprognostic (8.49e-2)" ZNF79 pT7 ENSG00000196152 "Zinc finger protein 79" Q15937 9 127424374-127445372 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 23.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" HPA028977 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 65: Non-specific - Cell growth & division" 7 Cytosol "Nucleoplasm, Plasma membrane" "HPA028977: " "unprognostic (1.84e-1)" "unprognostic (5.78e-3)" "unprognostic (1.18e-1)" "unprognostic (8.17e-2)" "unprognostic (1.62e-1)" "potential prognostic unfavorable (2.18e-6)" "unprognostic (7.28e-2)" "unprognostic (1.92e-3)" "unprognostic (1.24e-1)" "unprognostic (1.21e-1)" "potential prognostic favorable (8.29e-7)" "unprognostic (1.03e-3)" "unprognostic (2.30e-1)" "unprognostic (6.57e-2)" "unprognostic (1.36e-1)" "unprognostic (1.67e-2)" "unprognostic (7.64e-2)" "unprognostic (6.20e-2)" "unprognostic (2.66e-3)" "unprognostic (4.16e-3)" "unprognostic (1.14e-1)" "unprognostic (2.96e-3)" "unprognostic (1.72e-1)" "unprognostic (1.23e-3)" "unprognostic (1.03e-1)" "unprognostic (3.59e-1)" "unprognostic (1.16e-1)" "unprognostic (1.38e-2)" "unprognostic (3.36e-2)" "unprognostic (3.67e-2)" "unprognostic (9.21e-2)" ZNF790 "FLJ20350, MGC62100" ENSG00000197863 "Zinc finger protein 790" Q6PG37 19 36817428-36850787 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 100.2;Early spermatids: 184.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "HPA056134, HPA060288" Uncertain Approved Nucleoli NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 76: Non-specific - Metabolism" "Cluster 25: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" Nucleoli "HPA056134: , HPA060288: " "unprognostic (5.65e-3)" "unprognostic (4.51e-1)" "unprognostic (2.26e-1)" "unprognostic (1.96e-1)" "unprognostic (1.52e-1)" "potential prognostic favorable (9.27e-4)" "unprognostic (2.00e-1)" "unprognostic (7.09e-3)" "unprognostic (4.52e-2)" "unprognostic (8.14e-3)" "unprognostic (9.95e-3)" "unprognostic (5.99e-3)" "unprognostic (1.49e-2)" "unprognostic (3.12e-1)" "unprognostic (1.63e-2)" "unprognostic (1.23e-1)" "unprognostic (6.12e-2)" "unprognostic (2.41e-1)" "unprognostic (1.27e-1)" "unprognostic (9.45e-2)" "unprognostic (4.33e-2)" "unprognostic (1.49e-2)" "unprognostic (5.50e-2)" "unprognostic (1.46e-1)" "unprognostic (1.05e-3)" "unprognostic (1.42e-1)" "unprognostic (4.31e-1)" "unprognostic (4.65e-2)" "unprognostic (2.93e-1)" "unprognostic (3.73e-2)" "unprognostic (3.48e-1)" ZNF791 FLJ90396 ENSG00000173875 "Zinc finger protein 791" Q3KP31 19 12610918-12633840 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021537 Uncertain Approved Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 40: Non-specific - Mixed function" "Cluster 25: Non-specific - Transcription" "Cluster 23: Non-specific - Transcription" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 7 Nucleoplasm "HPA021537: " "unprognostic (4.63e-3)" "unprognostic (1.20e-1)" "unprognostic (4.85e-2)" "unprognostic (1.54e-1)" "unprognostic (9.04e-2)" "unprognostic (3.98e-1)" "unprognostic (7.76e-2)" "unprognostic (1.31e-1)" "unprognostic (1.20e-3)" "unprognostic (1.38e-2)" "validated prognostic favorable (5.61e-5)" "validated prognostic favorable (2.09e-4)" "unprognostic (4.16e-2)" "unprognostic (1.04e-1)" "unprognostic (1.47e-1)" "unprognostic (6.69e-3)" "unprognostic (2.67e-1)" "unprognostic (6.14e-2)" "unprognostic (7.41e-3)" "unprognostic (6.85e-2)" "unprognostic (4.77e-2)" "unprognostic (8.01e-2)" "unprognostic (4.21e-3)" "unprognostic (2.68e-2)" "potential prognostic favorable (1.12e-4)" "unprognostic (3.88e-2)" "unprognostic (1.60e-2)" "unprognostic (1.45e-1)" "unprognostic (1.45e-1)" "unprognostic (1.99e-1)" "unprognostic (6.52e-2)" ZNF792 FLJ38451 ENSG00000180884 "Zinc finger protein 792" Q3KQV3 19 34956354-34964229 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hematopoietic stem cells: 7.3;Kupffer cells: 6.1;Lymphatic endothelial cells: 6.7;Megakaryocyte progenitors: 6.8;Megakaryocyte-Erythroid progenitors: 8.2;Platelets: 26.9;Vascular endothelial cells: 8.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Lung - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in many" "HPA035157, HPA035158" Supported Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 15: Non-specific - Transcription" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 47: Platelets - Hemostasis" 46 "Nucleoplasm, Nuclear bodies" "HPA035157: , HPA035158: " "unprognostic (7.74e-3)" "unprognostic (2.99e-1)" "unprognostic (4.94e-1)" "unprognostic (2.00e-1)" "unprognostic (7.77e-3)" "unprognostic (3.98e-3)" "unprognostic (2.37e-1)" "unprognostic (9.84e-2)" "unprognostic (4.87e-2)" "potential prognostic favorable (8.15e-7)" "unprognostic (1.23e-3)" "unprognostic (3.51e-1)" "potential prognostic unfavorable (9.55e-5)" "unprognostic (1.20e-2)" "unprognostic (2.43e-1)" "unprognostic (3.50e-1)" "unprognostic (1.50e-1)" "unprognostic (4.91e-2)" "unprognostic (3.60e-2)" "potential prognostic unfavorable (3.34e-4)" "unprognostic (3.64e-1)" "unprognostic (9.81e-3)" "unprognostic (2.98e-1)" "potential prognostic favorable (1.06e-4)" "unprognostic (1.51e-1)" "unprognostic (2.59e-1)" "unprognostic (1.83e-1)" "unprognostic (1.31e-1)" "unprognostic (2.00e-1)" "unprognostic (2.55e-2)" ZNF793 ENSG00000188227 "Zinc finger protein 793" Q6ZN11 19 37506939-37548762 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Sertoli cells: 76.2;Thyrotrophs: 58.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" HPA034781 Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 32: Basophils - Transcription" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 15: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 1 Nucleoplasm "Nucleoli, Cytosol" "HPA034781: " "unprognostic (6.14e-3)" "unprognostic (5.64e-2)" "unprognostic (6.06e-2)" "unprognostic (2.24e-2)" "unprognostic (6.34e-2)" "unprognostic (4.00e-2)" "unprognostic (9.80e-2)" "unprognostic (7.41e-2)" "unprognostic (2.25e-2)" "unprognostic (2.57e-1)" "unprognostic (5.41e-2)" "potential prognostic favorable (1.03e-4)" "unprognostic (1.38e-2)" "unprognostic (1.11e-1)" "unprognostic (2.80e-1)" "unprognostic (1.30e-1)" "unprognostic (1.40e-1)" "unprognostic (1.02e-1)" "unprognostic (2.14e-1)" "unprognostic (3.08e-2)" "unprognostic (9.94e-2)" "unprognostic (1.38e-2)" "unprognostic (1.79e-1)" "unprognostic (4.03e-2)" "unprognostic (4.27e-3)" "unprognostic (1.50e-1)" "unprognostic (1.09e-1)" "unprognostic (2.85e-2)" "unprognostic (3.69e-2)" ZNF799 "HIT-40, MGC71805, ZNF842" ENSG00000196466 "Zinc finger protein 799" Q96GE5 19 12390016-12401271 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells" "HPA003150, HPA018683" Approved Approved "Nucleoplasm,Centriolar satellite" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 75: Ovary - Mixed function" "Cluster 54: Immune cells - T cell receptor" "Cluster 4: Non-specific - Transcription" "Cluster 110: Mural cells - ECM organization" 1 Nucleoplasm "Centriolar satellite" "HPA003150: , HPA018683: " "unprognostic (1.65e-3)" "unprognostic (9.33e-3)" "unprognostic (1.07e-1)" "unprognostic (1.21e-2)" "unprognostic (7.59e-2)" "unprognostic (3.71e-2)" "unprognostic (1.51e-1)" "unprognostic (6.55e-2)" "potential prognostic favorable (6.51e-4)" "potential prognostic unfavorable (6.60e-5)" "validated prognostic favorable (4.74e-4)" "validated prognostic favorable (3.79e-4)" "unprognostic (1.94e-3)" "unprognostic (7.94e-2)" "unprognostic (1.38e-1)" "unprognostic (9.08e-2)" "unprognostic (8.32e-2)" "unprognostic (2.94e-1)" "unprognostic (1.18e-2)" "unprognostic (1.97e-1)" "unprognostic (1.84e-1)" "unprognostic (8.90e-3)" "unprognostic (2.84e-2)" "unprognostic (2.85e-2)" "unprognostic (1.89e-3)" "unprognostic (3.14e-2)" "unprognostic (5.81e-3)" "unprognostic (8.99e-2)" "unprognostic (4.34e-1)" "unprognostic (7.17e-2)" "unprognostic (3.50e-1)" ZNF8 "HF.18, Zfp128" ENSG00000278129 "Zinc finger protein 8" P17098 19 58278955-58302791 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 14 "Astrocytes: 9.8;Bergmann glia: 11.3;Brain excitatory neurons: 9.4;Brain inhibitory neurons: 9.3;Choroid plexus epithelial cells: 12.5;Ependymal cells: 10.1;Microglia: 4.5;Oligodendrocyte progenitor cells: 9.7;Oligodendrocytes: 9.2;Other brain neurons: 7.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034797, HPA034798" Uncertain Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 22: Non-specific - Basic cellular functions" 14 "Nucleoplasm, Nuclear bodies" "HPA034797: , HPA034798: " "unprognostic (1.57e-2)" "unprognostic (1.53e-1)" "unprognostic (1.51e-1)" "unprognostic (1.18e-2)" "unprognostic (6.35e-2)" "unprognostic (8.71e-2)" "unprognostic (2.82e-2)" "unprognostic (9.67e-3)" "unprognostic (7.31e-2)" "unprognostic (3.29e-1)" "unprognostic (8.83e-3)" "unprognostic (8.58e-2)" "unprognostic (2.89e-1)" "unprognostic (3.51e-1)" "unprognostic (2.47e-1)" "unprognostic (3.03e-2)" "unprognostic (1.43e-3)" "unprognostic (6.80e-2)" "unprognostic (1.24e-2)" "unprognostic (1.89e-2)" "unprognostic (4.66e-3)" "unprognostic (2.28e-3)" "unprognostic (1.10e-1)" "unprognostic (1.13e-1)" "unprognostic (4.59e-2)" "unprognostic (4.28e-2)" "unprognostic (8.17e-2)" ZNF80 pT17 ENSG00000174255 "Zinc finger protein 80" P51504 3 114234631-114237578 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 5 "lymphoid tissue: 2.9" "Group enriched" "Detected in some" 6 "NK-cells: 3.3;Platelets: 2.8;T-cells: 9.6" "Cell type enriched" "Detected in single" 15 "leukocyte: 7.2" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 1.2" "Lineage enriched" "Detected in single" 4 "T-cells: 1.2" "Cancer enhanced" "Detected in single" "lymphoma: 1.0" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Kidney - T-cells, Minor Salivary Gland - T-cells, Prostate - T-cells, Spleen - B-cells (Spleen), Thyroid gland - T-cells" HPA065484 Uncertain Approved Nucleoplasm,Nucleoli NA NA "Cluster 18: Lymphoid tissue - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 9: T-cells - Adaptive immunity: Regulation" 9 Nucleoli Nucleoplasm "HPA065484: " "unprognostic (1.16e-1)" ZNF800 ENSG00000048405 "Zinc finger protein 800" Q2TB10 7 127346790-127431924 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 70.4" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023090, HPA052194" Approved Supported "Nucleoli,Nucleoli rim,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 16: Non-specific - Transcription" "Cluster 39: Non-specific - Transcription" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 2 "Nucleoli, Nucleoli rim" Cytosol "HPA023090: , HPA052194: " "unprognostic (2.39e-2)" "unprognostic (8.04e-2)" "unprognostic (7.75e-2)" "unprognostic (4.17e-3)" "unprognostic (2.60e-1)" "unprognostic (4.04e-2)" "unprognostic (2.07e-1)" "unprognostic (3.32e-1)" "unprognostic (1.54e-1)" "potential prognostic unfavorable (4.90e-4)" "potential prognostic favorable (8.08e-7)" "unprognostic (2.35e-2)" "unprognostic (2.87e-1)" "unprognostic (5.81e-2)" "unprognostic (2.18e-1)" "unprognostic (7.88e-2)" "unprognostic (2.19e-2)" "unprognostic (1.94e-1)" "unprognostic (1.90e-1)" "unprognostic (7.63e-2)" "unprognostic (3.86e-1)" "unprognostic (4.28e-2)" "unprognostic (4.25e-2)" "unprognostic (1.28e-1)" "unprognostic (5.26e-2)" "unprognostic (2.82e-2)" "unprognostic (1.83e-2)" "unprognostic (1.68e-1)" "unprognostic (1.11e-1)" "unprognostic (9.28e-3)" "unprognostic (3.51e-1)" ZNF804A C2orf10 ENSG00000170396 "Zinc finger protein 804A" Q7Z570 2 184598529-184939492 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.5;retina: 3.5" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 401.4;Brain inhibitory neurons: 495.3;Hematopoietic stem cells: 423.6;Megakaryocyte progenitors: 307.7;Megakaryocyte-Erythroid progenitors: 584.4;Oligodendrocyte progenitor cells: 286.8;Other brain neurons: 466.3;Podocytes: 832.6;Retinal amacrine cells: 428.2;Retinal bipolar cells: 470.3" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in single" 4 "Glioblastoma Multiforme (TCGA): 1.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "lymphoma: 8.9;Neuroblastoma: 10.8" "Colon - Colon enteroendocrine cells, Kidney - Podocytes, Prostate - Fibroblasts, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029195 Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 3: Rhabdoid - Membrane components" "Cluster 109: Neurons - Neuronal signaling" 1 "Endoplasmic reticulum" "HPA029195: " "unprognostic (2.68e-1)" "unprognostic (1.70e-2)" "potential prognostic favorable (7.84e-4)" ZNF804B FLJ32110 ENSG00000182348 "Zinc finger protein 804B" A4D1E1 7 88759700-89338528 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 4 "thyroid gland: 3.7" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 257.6;Brain inhibitory neurons: 324.1;Hematopoietic stem cells: 395.0;Megakaryocyte-Erythroid progenitors: 319.4;Other brain neurons: 250.7;Pancreatic acinar cells: 281.5;Proximal tubule cells: 490.5;Retinal bipolar cells: 1666.3;Thyrotrophs: 349.3" "Cell type enhanced" "Detected in all" "eccentric medium spiny neuron: 1344.8;LAMP5-LHX6 and Chandelier: 1366.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA026702 Uncertain NA NA "Cluster 33: Thyroid gland - Tissue development" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "HPA026702: " ZNF805 ENSG00000204524 "Zinc finger protein 805" Q5CZA5 19 57240632-57262728 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "HPA046330, HPA058895" Uncertain Approved Nucleoplasm NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 40: Non-specific - Mixed function" "Cluster 55: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 4 Nucleoplasm "HPA046330: , HPA058895: " "unprognostic (7.36e-3)" "unprognostic (4.41e-2)" "unprognostic (2.32e-1)" "unprognostic (2.76e-1)" "unprognostic (1.65e-2)" "unprognostic (2.26e-2)" "unprognostic (4.65e-2)" "unprognostic (3.70e-2)" "unprognostic (6.67e-3)" "unprognostic (5.03e-1)" "unprognostic (1.96e-1)" "unprognostic (1.02e-2)" "unprognostic (2.95e-1)" "unprognostic (1.62e-1)" "unprognostic (8.33e-2)" "unprognostic (3.33e-1)" "unprognostic (2.24e-2)" "unprognostic (4.43e-2)" "unprognostic (3.38e-1)" "unprognostic (1.10e-1)" "unprognostic (8.57e-3)" "unprognostic (2.39e-1)" "unprognostic (2.04e-1)" "unprognostic (2.58e-2)" "unprognostic (4.69e-2)" "unprognostic (1.97e-2)" "unprognostic (4.18e-2)" "unprognostic (3.26e-1)" "unprognostic (2.89e-2)" "unprognostic (4.27e-2)" "unprognostic (3.47e-2)" ZNF808 ENSG00000198482 "Zinc finger protein 808" Q8N4W9 19 52527652-52564464 "Predicted intracellular proteins, Transcription factors" Transcription DNA-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 81.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" NA NA "Cluster 32: Basophils - Transcription" "Cluster 40: Non-specific - Mixed function" "Cluster 44: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" "unprognostic (2.33e-2)" "unprognostic (1.58e-1)" "unprognostic (6.95e-2)" "unprognostic (2.61e-2)" "unprognostic (8.55e-2)" "unprognostic (5.29e-2)" "unprognostic (6.90e-3)" "unprognostic (1.10e-3)" "potential prognostic favorable (3.09e-4)" "unprognostic (1.86e-2)" "unprognostic (1.40e-1)" "unprognostic (1.56e-1)" "unprognostic (2.63e-1)" "unprognostic (2.31e-2)" "unprognostic (8.07e-2)" "unprognostic (3.47e-1)" "unprognostic (3.09e-1)" "unprognostic (2.69e-2)" "unprognostic (5.96e-3)" "unprognostic (1.51e-1)" "unprognostic (1.08e-2)" "unprognostic (1.61e-1)" "unprognostic (3.46e-1)" "unprognostic (7.44e-2)" "unprognostic (4.62e-2)" "unprognostic (2.42e-1)" ZNF81 "HFZ20, MRX45" ENSG00000197779 "Zinc finger protein 81" P51508 X 47836902-48002561 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001689 Approved NA NA "Cluster 41: Basophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "HPA001689: " "unprognostic (5.27e-2)" "unprognostic (2.14e-2)" "unprognostic (1.45e-1)" "unprognostic (1.76e-1)" "unprognostic (1.43e-1)" "unprognostic (1.94e-1)" "potential prognostic favorable (9.71e-5)" "unprognostic (1.04e-2)" "unprognostic (4.56e-2)" "unprognostic (1.40e-2)" "unprognostic (3.59e-1)" "unprognostic (3.31e-1)" "unprognostic (2.48e-1)" "unprognostic (5.19e-2)" "unprognostic (1.11e-1)" "unprognostic (1.48e-1)" "unprognostic (1.47e-2)" "unprognostic (9.54e-2)" "unprognostic (1.17e-1)" "unprognostic (1.89e-1)" "unprognostic (1.16e-1)" "unprognostic (1.94e-2)" "unprognostic (3.67e-2)" "unprognostic (1.87e-1)" "unprognostic (5.94e-2)" "unprognostic (8.19e-2)" "unprognostic (8.57e-2)" "unprognostic (9.16e-2)" "unprognostic (1.29e-1)" "unprognostic (1.20e-1)" ZNF813 FLJ16542 ENSG00000198346 "Zinc finger protein 813" Q6ZN06 19 53467733-53496255 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 32.3;Prostatic glandular cells: 33.8;Syncytiotrophoblasts: 30.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Liver - Vascular endothelial cells, Prostate - Prostate glandular cells, Testis - Spermatogonia" HPA056406 Uncertain Approved Vesicles NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 4: Non-specific - Transcription" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 6 Vesicles "HPA056406: " "unprognostic (1.19e-2)" "unprognostic (2.63e-2)" "unprognostic (3.18e-1)" "potential prognostic unfavorable (6.96e-4)" "unprognostic (3.55e-1)" "unprognostic (3.44e-2)" "unprognostic (2.73e-1)" "unprognostic (2.40e-2)" "unprognostic (5.51e-2)" "potential prognostic favorable (5.03e-5)" "unprognostic (3.81e-3)" "unprognostic (1.70e-3)" "unprognostic (9.21e-2)" "unprognostic (7.74e-2)" "unprognostic (1.23e-2)" "unprognostic (6.55e-2)" "unprognostic (4.13e-2)" "unprognostic (3.01e-2)" "unprognostic (1.09e-2)" "unprognostic (2.66e-1)" "unprognostic (6.49e-2)" "unprognostic (4.07e-2)" "unprognostic (2.37e-1)" "unprognostic (3.69e-3)" "unprognostic (7.99e-2)" "unprognostic (2.15e-1)" "unprognostic (1.07e-1)" "unprognostic (3.02e-2)" ZNF814 ENSG00000204514 "Zinc finger protein 814" B7Z6K7 19 57848731-57889074 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 211.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA043800, HPA053762, HPA072145" Approved Uncertain Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" Nucleoplasm "HPA043800: , HPA053762: , HPA072145: " "unprognostic (8.46e-3)" "unprognostic (2.07e-1)" "unprognostic (7.74e-2)" "unprognostic (2.00e-1)" "unprognostic (3.73e-1)" "unprognostic (1.20e-1)" "unprognostic (1.94e-1)" "unprognostic (2.40e-1)" "unprognostic (1.63e-2)" "unprognostic (7.67e-2)" "validated prognostic favorable (3.43e-4)" "validated prognostic favorable (1.79e-4)" "potential prognostic favorable (7.67e-4)" "unprognostic (5.45e-2)" "unprognostic (1.01e-2)" "unprognostic (1.43e-1)" "unprognostic (6.67e-2)" "unprognostic (2.06e-1)" "unprognostic (2.68e-1)" "unprognostic (5.34e-3)" "unprognostic (1.16e-1)" "potential prognostic favorable (6.50e-4)" "unprognostic (5.52e-3)" "unprognostic (3.41e-3)" "unprognostic (3.08e-1)" "unprognostic (3.26e-2)" "potential prognostic unfavorable (5.86e-4)" "unprognostic (1.19e-1)" "unprognostic (1.68e-1)" "unprognostic (8.98e-2)" "unprognostic (1.89e-3)" ZNF816 ZNF816A ENSG00000180257 "Zinc finger protein 816" Q0VGE8 19 52949379-52962911 "Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 1.8;Basal prostatic cells: 1.5;Bergmann glia: 1.7;Brain excitatory neurons: 1.4;Choroid plexus epithelial cells: 2.2;Ependymal cells: 2.3;Medullary thymic epithelial cells: 7.2;Megakaryocyte progenitors: 1.5;Microglia: 4.8;Oligodendrocytes: 1.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA042466 Uncertain Approved "Nucleoli rim" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 22: Non-specific - Basic cellular functions" 1 "Nucleoli rim" "HPA042466: " "potential prognostic favorable (1.59e-6)" "unprognostic (1.30e-2)" "unprognostic (2.32e-1)" "unprognostic (2.03e-1)" "unprognostic (1.33e-1)" "unprognostic (3.46e-1)" "potential prognostic unfavorable (7.06e-4)" "unprognostic (3.18e-3)" "unprognostic (1.40e-3)" "potential prognostic favorable (1.71e-6)" "unprognostic (1.13e-1)" "unprognostic (1.25e-2)" "unprognostic (3.39e-3)" "unprognostic (8.75e-2)" "unprognostic (1.66e-1)" "unprognostic (7.39e-2)" "unprognostic (1.72e-2)" "unprognostic (1.20e-1)" "unprognostic (2.59e-1)" "unprognostic (9.98e-2)" "unprognostic (2.58e-1)" "unprognostic (4.05e-1)" "unprognostic (1.63e-1)" "unprognostic (3.24e-2)" "unprognostic (1.10e-2)" "unprognostic (1.76e-2)" "unprognostic (2.83e-2)" "unprognostic (1.77e-1)" "unprognostic (9.15e-2)" "unprognostic (1.73e-1)" ZNF816-ZNF321P ZNF816-ZNF321 ENSG00000221874 "ZNF816-ZNF321P readthrough" 19 52928475-52962823 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "prostate: 1.7" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 20.9;Endometrial luminal cells: 13.5;Mucous neck cells: 9.9;Prostatic hillock cells: 11.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA051271 Uncertain Uncertain Nucleoplasm NA NA "Cluster 38: Non-specific - Basic cellular processes" "Cluster 4: Non-specific - Transcription" "Cluster 51: Secretory epithelial cells - Mixed function" Nucleoplasm "HPA051271: " "unprognostic (3.12e-1)" ZNF821 ENSG00000102984 "Zinc finger protein 821" O75541 16 71859680-71895336 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 25.3;testis: 19.8" "Cell type enhanced" "Detected in many" "Early spermatids: 183.5;Enterocytes: 193.7;Late primary spermatocytes: 198.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 9.5;naive B-cell: 13.5;T-reg: 5.7" "Group enriched" "Detected in many" 9 "B-cells: 13.5;T-cells: 5.7" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Spleen - B-cells (Spleen), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036372, HPA042742" Enhanced Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 71: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 65: Non-specific - Cell growth & division" 2 "Nucleoplasm, Nuclear speckles" "HPA036372: , HPA042742: " "unprognostic (1.13e-1)" "unprognostic (3.08e-1)" "unprognostic (1.21e-1)" "unprognostic (1.05e-1)" "unprognostic (3.65e-2)" "unprognostic (2.12e-2)" "unprognostic (8.15e-3)" "unprognostic (2.00e-3)" "unprognostic (2.10e-1)" "unprognostic (4.42e-2)" "validated prognostic favorable (9.17e-10)" "validated prognostic favorable (1.95e-5)" "unprognostic (1.02e-2)" "unprognostic (1.14e-2)" "unprognostic (8.83e-2)" "unprognostic (1.27e-2)" "unprognostic (8.81e-2)" "unprognostic (2.53e-1)" "unprognostic (3.44e-2)" "unprognostic (6.17e-2)" "unprognostic (2.64e-1)" "unprognostic (2.58e-3)" "unprognostic (4.50e-2)" "unprognostic (1.74e-1)" "unprognostic (4.11e-1)" "unprognostic (6.79e-2)" "unprognostic (6.18e-2)" "unprognostic (1.95e-1)" "unprognostic (2.57e-1)" "unprognostic (3.44e-1)" "unprognostic (1.52e-1)" ZNF823 HSZFP36 ENSG00000197933 "Zinc finger protein 823" P16415 19 11721265-11739009 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 81.7;Esophageal apical cells: 125.3;Extravillous trophoblasts: 63.2;Migrating cytotrophoblasts: 88.1;Syncytiotrophoblasts: 84.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 35: Non-specific - DNA binding" "Cluster 4: Non-specific - Transcription" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 2 "potential prognostic favorable (4.49e-4)" "unprognostic (6.45e-2)" "unprognostic (8.31e-2)" "unprognostic (1.78e-2)" "unprognostic (1.25e-2)" "unprognostic (3.47e-2)" "unprognostic (5.64e-2)" "potential prognostic favorable (5.53e-4)" "potential prognostic favorable (1.50e-4)" "unprognostic (1.76e-1)" "potential prognostic favorable (2.79e-5)" "unprognostic (9.06e-3)" "unprognostic (4.71e-2)" "unprognostic (4.97e-1)" "unprognostic (1.72e-2)" "unprognostic (5.87e-2)" "unprognostic (1.58e-1)" "unprognostic (4.06e-2)" "unprognostic (5.78e-3)" "unprognostic (1.49e-1)" "unprognostic (2.85e-1)" "unprognostic (3.26e-1)" "unprognostic (2.51e-1)" "unprognostic (3.44e-2)" "unprognostic (1.95e-3)" "unprognostic (1.77e-1)" "unprognostic (2.65e-2)" "unprognostic (4.85e-3)" "unprognostic (1.98e-1)" "unprognostic (2.35e-1)" "unprognostic (1.04e-1)" ZNF827 ENSG00000151612 "Zinc finger protein 827" Q17R98 4 145757627-145938823 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Prostatic glandular cells: 1374.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Prostate glandular cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021166 Uncertain Approved Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 69: Skin cancer - ECM organization" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 11 Nucleoplasm "HPA021166: " "unprognostic (2.18e-1)" "unprognostic (2.10e-1)" "unprognostic (1.37e-1)" "unprognostic (4.21e-2)" "unprognostic (6.67e-2)" "unprognostic (4.04e-2)" "unprognostic (9.91e-2)" "unprognostic (1.17e-1)" "unprognostic (2.53e-2)" "unprognostic (6.77e-2)" "validated prognostic favorable (2.74e-5)" "validated prognostic favorable (7.43e-4)" "unprognostic (4.55e-2)" "unprognostic (1.25e-1)" "unprognostic (3.01e-3)" "unprognostic (5.53e-2)" "unprognostic (1.20e-1)" "unprognostic (4.35e-3)" "unprognostic (3.49e-1)" "unprognostic (1.80e-1)" "unprognostic (2.67e-2)" "unprognostic (2.56e-1)" "unprognostic (1.30e-1)" "unprognostic (2.74e-1)" "unprognostic (3.01e-1)" "unprognostic (3.53e-2)" "unprognostic (1.07e-1)" "unprognostic (7.47e-3)" "unprognostic (7.70e-2)" ZNF829 DKFZp779O175 ENSG00000185869 "Zinc finger protein 829" Q3KNS6 19 36888124-36916291 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 6.2" "Cell type enriched" "Detected in many" 4 "Early spermatids: 335.9" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 6.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" HPA073073 Approved "Nucleoplasm,Nuclear bodies" No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 57: Testis - Spermatogenesis" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 6 Nucleoplasm "Nuclear bodies" "HPA073073: " "unprognostic (2.72e-2)" "unprognostic (5.49e-2)" "unprognostic (1.31e-1)" "unprognostic (6.74e-3)" "potential prognostic favorable (6.29e-4)" "unprognostic (1.34e-1)" "unprognostic (1.11e-1)" "unprognostic (1.50e-2)" "validated prognostic favorable (6.80e-6)" "validated prognostic favorable (1.04e-4)" "unprognostic (2.31e-2)" "unprognostic (2.40e-1)" "unprognostic (2.75e-1)" "unprognostic (4.21e-1)" "unprognostic (3.11e-1)" "unprognostic (1.22e-1)" "unprognostic (2.25e-2)" "unprognostic (1.44e-2)" "unprognostic (1.57e-1)" "unprognostic (2.69e-3)" "unprognostic (3.41e-1)" "unprognostic (6.87e-2)" "unprognostic (1.72e-1)" ZNF83 "FLJ11015, HPF1, ZNF816B" ENSG00000167766 "Zinc finger protein 83" P51522 19 52594060-52690559 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ocular epithelial cells: 359.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells" HPA025970 Approved Approved Nucleoplasm NA NA "Cluster 11: T-cells - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 100: Stratified epithelial cells - Barrier functions" Nucleoplasm "HPA025970: " "potential prognostic favorable (1.48e-5)" "unprognostic (1.18e-2)" "unprognostic (3.50e-1)" "unprognostic (8.28e-2)" "unprognostic (4.88e-3)" "unprognostic (1.34e-1)" "unprognostic (2.28e-1)" "unprognostic (1.97e-1)" "unprognostic (3.39e-2)" "unprognostic (7.92e-3)" "potential prognostic unfavorable (2.28e-5)" "unprognostic (3.71e-1)" "unprognostic (1.01e-3)" "unprognostic (4.49e-3)" "unprognostic (1.50e-1)" "unprognostic (1.49e-2)" "unprognostic (1.25e-1)" "unprognostic (1.12e-2)" "unprognostic (6.63e-2)" "unprognostic (1.32e-1)" "unprognostic (2.28e-1)" "unprognostic (2.36e-1)" "unprognostic (2.16e-3)" "unprognostic (1.11e-3)" "unprognostic (1.79e-1)" "unprognostic (8.01e-2)" "unprognostic (1.12e-3)" "unprognostic (2.58e-1)" "unprognostic (5.44e-2)" "unprognostic (7.74e-2)" "unprognostic (1.09e-1)" ZNF830 "CCDC16, MGC20398, OMCG1" ENSG00000198783 "Zinc finger protein 830" Q96NB3 17 34961540-34963777 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, mRNA processing, mRNA splicing" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024754, HPA027211" Enhanced Enhanced Nucleoplasm NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 31: Non-specific - Transcription" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 17: Non-specific - RNA processing" 39 Nucleoplasm "HPA024754: , HPA027211: " "unprognostic (8.18e-2)" "unprognostic (3.83e-1)" "unprognostic (2.55e-1)" "unprognostic (1.58e-1)" "unprognostic (7.77e-2)" "unprognostic (3.74e-2)" "unprognostic (2.85e-1)" "unprognostic (2.67e-3)" "unprognostic (2.33e-1)" "potential prognostic unfavorable (8.21e-4)" "potential prognostic favorable (5.15e-6)" "unprognostic (4.08e-3)" "unprognostic (4.43e-1)" "unprognostic (8.78e-3)" "unprognostic (6.30e-3)" "unprognostic (1.49e-1)" "unprognostic (6.36e-3)" "unprognostic (2.13e-1)" "unprognostic (6.51e-2)" "unprognostic (1.86e-2)" "unprognostic (2.50e-1)" "unprognostic (1.19e-1)" "unprognostic (3.05e-2)" "unprognostic (5.33e-3)" "potential prognostic favorable (1.61e-4)" "unprognostic (6.39e-2)" "unprognostic (9.85e-2)" "unprognostic (6.78e-2)" "unprognostic (4.92e-1)" "unprognostic (4.95e-2)" "unprognostic (1.88e-1)" ZNF831 "C20orf174, dJ492J12.1" ENSG00000124203 "Zinc finger protein 831" Q5JPB2 20 59123381-59259113 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 5.8" "Cell type enhanced" "Detected in many" "B-cells: 70.0;Brain excitatory neurons: 32.9;Brain inhibitory neurons: 26.5;Innate lymphoid cells: 35.5;Lactotrophs: 32.0;Lymphatic endothelial cells: 46.3;NK-cells: 113.4;Other brain neurons: 33.6;Sertoli cells: 26.0;Somatotrophs: 28.9;T-cells: 274.4;Thyrotrophs: 28.8" "Cell type enhanced" "Detected in many" "leukocyte: 222.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "NK-cells: 1.2;T-cells: 2.2" "Cancer enhanced" "Detected in single" "Rhabdoid: 2.2" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Minor Salivary Gland - T-cells, Prostate - T-cells, Skin - T-cells, Testis - Sertoli cells, Thyroid gland - T-cells" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 25 "amygdala: 6.3;basal ganglia: 5.7;cerebral cortex: 4.6;hippocampal formation: 6.9;olfactory bulb: 7.5" HPA016839 Uncertain NA NA "Cluster 1: T-cells - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 51: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 9: T-cells - Adaptive immunity: Regulation" "HPA016839: " "unprognostic (9.26e-3)" "unprognostic (4.14e-1)" ZNF835 BC37295_3 ENSG00000127903 "Zinc finger protein 835" Q9Y2P0 19 56661980-56671783 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 5.1;Oocytes: 9.2;Retinal ganglion cells: 7.7;Retinal horizontal cells: 6.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Heart muscle - Cardiomyocytes" HPA051136 Uncertain Approved "Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Basal body" Yes NA "Cluster 24: Non-specific - Transcription" "Cluster 65: Brain - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 54 Microtubules "Cytokinetic bridge, Mitotic spindle, Primary cilium, Basal body" "HPA051136: " "unprognostic (3.26e-1)" "unprognostic (1.54e-1)" "unprognostic (1.43e-1)" "unprognostic (8.94e-2)" "unprognostic (6.59e-2)" "validated prognostic favorable (7.30e-5)" "validated prognostic favorable (1.52e-4)" "unprognostic (5.88e-2)" "unprognostic (5.00e-2)" "unprognostic (2.31e-2)" "unprognostic (2.90e-2)" "unprognostic (7.94e-2)" "unprognostic (3.06e-1)" "unprognostic (2.19e-1)" "unprognostic (1.28e-1)" "unprognostic (3.86e-2)" ZNF836 FLJ16287 ENSG00000196267 "Zinc finger protein 836" Q6ZNA1 19 52153864-52171643 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 25.5" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 6.4;Epididymal basal cells: 4.8;Esophageal apical cells: 7.9;Loop of henle epithelial cells: 6.8;Papillary tip epithelial cells: 8.8;Podocytes: 6.7;Proximal tubule cells: 7.1;Renal collecting duct intercalated cells: 7.1;Renal collecting duct principal cells: 15.5;Renal connecting tubule cells: 10.5" "Low cell type specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 16: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 105: Non-specific - Mixed function" 2 "unprognostic (5.59e-3)" "unprognostic (2.53e-2)" "unprognostic (1.39e-1)" "unprognostic (4.43e-2)" "unprognostic (1.60e-1)" "unprognostic (9.60e-2)" "unprognostic (2.37e-1)" "unprognostic (1.69e-1)" "unprognostic (4.32e-3)" "unprognostic (1.96e-1)" "validated prognostic favorable (6.08e-4)" "validated prognostic favorable (7.93e-4)" "unprognostic (7.16e-2)" "unprognostic (6.85e-2)" "unprognostic (1.05e-1)" "unprognostic (1.37e-3)" "unprognostic (2.18e-1)" "unprognostic (6.71e-2)" "unprognostic (1.18e-1)" "unprognostic (2.50e-1)" "unprognostic (1.90e-1)" "unprognostic (1.37e-2)" "unprognostic (4.25e-1)" "unprognostic (1.63e-2)" "unprognostic (1.25e-2)" "unprognostic (2.93e-1)" "unprognostic (4.51e-2)" "unprognostic (4.64e-2)" "unprognostic (1.86e-1)" "unprognostic (2.58e-1)" "unprognostic (2.92e-1)" ZNF837 ENSG00000152475 "Zinc finger protein 837" Q96EG3 19 58367618-58381030 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Epicardial cells: 13.6;Epididymal principal cells: 11.2;Oocytes: 18.4;Tuft cells: 23.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" HPA042833 Uncertain Approved Nucleoli NA NA "Cluster 70: Non-specific - Protein processing" "Cluster 46: Brainstem - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 95: Tuft cells - Chemosensory signaling" 68 Nucleoli "HPA042833: " "unprognostic (2.24e-2)" "unprognostic (2.39e-1)" "unprognostic (1.44e-1)" "unprognostic (1.45e-2)" "unprognostic (1.40e-2)" "unprognostic (3.74e-1)" "unprognostic (4.30e-1)" "unprognostic (9.67e-2)" "unprognostic (4.06e-3)" "unprognostic (2.57e-2)" "unprognostic (3.08e-1)" "unprognostic (1.34e-1)" "unprognostic (1.23e-2)" "unprognostic (4.05e-2)" "unprognostic (4.46e-2)" "unprognostic (2.86e-1)" "unprognostic (7.74e-2)" "unprognostic (9.94e-2)" "unprognostic (2.76e-2)" "unprognostic (1.13e-3)" "unprognostic (2.79e-2)" "unprognostic (1.15e-1)" "unprognostic (6.97e-2)" "unprognostic (9.75e-2)" "unprognostic (6.30e-2)" "potential prognostic favorable (5.10e-4)" "unprognostic (2.77e-1)" "unprognostic (3.04e-2)" "unprognostic (1.64e-1)" ZNF839 C14orf131 ENSG00000022976 "Zinc finger protein 839" A8K0R7 14 102317377-102342702 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 54.3;Myonuclei: 49.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020434 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 39: Testis - Nuclear processes" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 7: Non-specific - Transcription" "Plasma membrane" Nucleoplasm "HPA020434: " "unprognostic (8.86e-3)" "unprognostic (1.39e-1)" "unprognostic (2.96e-2)" "unprognostic (1.92e-1)" "unprognostic (1.69e-1)" "unprognostic (1.05e-1)" "unprognostic (4.58e-2)" "unprognostic (8.17e-2)" "unprognostic (1.51e-1)" "unprognostic (1.12e-1)" "unprognostic (2.00e-3)" "potential prognostic favorable (5.50e-5)" "unprognostic (9.44e-2)" "unprognostic (1.11e-1)" "unprognostic (1.67e-1)" "unprognostic (2.57e-1)" "unprognostic (1.59e-1)" "unprognostic (1.84e-1)" "unprognostic (1.04e-1)" "unprognostic (3.81e-3)" "unprognostic (1.40e-2)" "unprognostic (1.35e-3)" "unprognostic (4.93e-2)" "unprognostic (7.58e-2)" "unprognostic (1.20e-2)" "unprognostic (1.10e-1)" "unprognostic (3.66e-1)" "unprognostic (7.19e-3)" "unprognostic (9.28e-2)" "unprognostic (3.44e-2)" "unprognostic (6.82e-2)" ZNF84 HPF2 ENSG00000198040 "Zinc finger protein 84" P51523 12 133037292-133063304 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028860 Approved Approved Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 65: Brain - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 7 Nucleoplasm "HPA028860: " "unprognostic (1.45e-1)" "unprognostic (4.87e-1)" "unprognostic (1.81e-1)" "unprognostic (6.10e-2)" "unprognostic (4.95e-3)" "unprognostic (8.36e-2)" "unprognostic (2.92e-1)" "unprognostic (4.13e-2)" "unprognostic (6.30e-2)" "unprognostic (2.46e-2)" "potential prognostic favorable (3.08e-4)" "unprognostic (2.02e-3)" "unprognostic (3.65e-2)" "unprognostic (2.60e-3)" "unprognostic (4.10e-2)" "unprognostic (2.45e-1)" "unprognostic (1.32e-1)" "unprognostic (5.99e-3)" "unprognostic (4.92e-2)" "unprognostic (2.66e-1)" "unprognostic (1.65e-1)" "unprognostic (1.53e-2)" "unprognostic (1.21e-2)" "unprognostic (9.74e-2)" "unprognostic (2.35e-2)" "unprognostic (3.63e-2)" "unprognostic (6.90e-3)" "unprognostic (1.12e-1)" "unprognostic (2.21e-1)" "unprognostic (4.57e-3)" "unprognostic (1.72e-2)" ZNF841 LOC284371 ENSG00000197608 "Zinc finger protein 841" Q6ZN19 19 52064465-52095765 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epicardial cells: 13.6;Esophageal apical cells: 6.0;Tuft cells: 11.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" "unprognostic (4.57e-3)" "unprognostic (2.05e-1)" "unprognostic (3.37e-1)" "unprognostic (2.47e-2)" "unprognostic (3.25e-2)" "unprognostic (8.89e-2)" "unprognostic (5.99e-2)" "unprognostic (1.40e-1)" "unprognostic (2.43e-2)" "unprognostic (3.90e-2)" "unprognostic (1.52e-1)" "potential prognostic favorable (5.61e-4)" "unprognostic (3.84e-2)" "unprognostic (3.29e-2)" "unprognostic (1.63e-1)" "unprognostic (1.44e-1)" "unprognostic (3.03e-2)" "unprognostic (4.05e-2)" "unprognostic (2.51e-2)" "unprognostic (1.55e-1)" "unprognostic (3.77e-2)" "unprognostic (3.47e-1)" "unprognostic (1.51e-3)" "unprognostic (5.20e-2)" "unprognostic (5.13e-2)" "unprognostic (4.11e-1)" "unprognostic (2.93e-2)" "unprognostic (3.83e-2)" "unprognostic (3.07e-1)" "unprognostic (5.50e-3)" "unprognostic (9.22e-2)" ZNF843 MGC46336 ENSG00000176723 "Zinc finger protein 843" Q8N446 16 31432593-31443160 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 7.8;Myonuclei: 10.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 1.7" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes" "HPA030911, HPA030912, HPA077945" Uncertain Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 65: Brain - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 55: Myocytes - Oxidative muscle function" 6 Nucleoplasm "Nuclear speckles" "HPA030911: , HPA030912: , HPA077945: " "unprognostic (1.29e-1)" "unprognostic (2.31e-1)" "unprognostic (2.74e-1)" "unprognostic (3.30e-1)" "unprognostic (1.65e-1)" "unprognostic (8.33e-2)" "unprognostic (1.03e-1)" "unprognostic (4.08e-2)" "unprognostic (4.25e-2)" "unprognostic (8.32e-2)" "unprognostic (2.28e-2)" "unprognostic (1.73e-1)" "potential prognostic unfavorable (2.18e-5)" "unprognostic (1.04e-1)" ZNF844 FLJ14959 ENSG00000223547 "Zinc finger protein 844" Q08AG5 19 12064731-12081565 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 13.5;Bergmann glia: 22.2;Choroid plexus epithelial cells: 25.7;Distal convoluted tubule cells: 35.3;Loop of henle epithelial cells: 32.0;Papillary tip epithelial cells: 15.1;Podocytes: 16.5;Proximal tubule cells: 31.7;Renal collecting duct intercalated cells: 24.4;Renal collecting duct principal cells: 19.6;Renal connecting tubule cells: 24.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" HPA046982 Approved NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 25: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 11 "HPA046982: " "unprognostic (4.05e-3)" "unprognostic (3.31e-2)" "unprognostic (1.58e-1)" "unprognostic (7.70e-2)" "unprognostic (4.18e-1)" "unprognostic (1.08e-1)" "unprognostic (1.21e-2)" "unprognostic (8.92e-2)" "unprognostic (7.80e-2)" "validated prognostic favorable (1.69e-8)" "validated prognostic favorable (2.54e-4)" "potential prognostic favorable (4.79e-7)" "unprognostic (2.57e-1)" "unprognostic (9.44e-2)" "unprognostic (1.19e-2)" "unprognostic (2.65e-2)" "unprognostic (5.12e-3)" "unprognostic (3.14e-1)" "unprognostic (1.56e-1)" "unprognostic (7.22e-2)" "unprognostic (3.84e-3)" "unprognostic (1.89e-1)" "unprognostic (2.00e-2)" "unprognostic (2.22e-2)" "unprognostic (5.96e-2)" "unprognostic (2.87e-2)" "unprognostic (8.81e-2)" "unprognostic (2.07e-1)" "unprognostic (1.54e-1)" "unprognostic (2.63e-2)" ZNF845 ENSG00000213799 "Zinc finger protein 845" Q96IR2 19 53333749-53356906 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 19.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Macrophages, Testis - Spermatogonia" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 7: Non-specific - Ribosome" "Cluster 4: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 10 "unprognostic (4.64e-2)" "unprognostic (3.56e-3)" "unprognostic (3.01e-3)" "potential prognostic unfavorable (7.30e-4)" "unprognostic (2.39e-1)" "unprognostic (1.39e-1)" "unprognostic (2.23e-1)" "unprognostic (1.98e-2)" "unprognostic (5.51e-2)" "unprognostic (4.76e-3)" "potential prognostic favorable (3.45e-7)" "unprognostic (1.10e-3)" "unprognostic (3.12e-2)" "unprognostic (1.97e-3)" "unprognostic (7.93e-2)" "unprognostic (2.05e-1)" "unprognostic (6.13e-2)" "unprognostic (1.04e-1)" "unprognostic (7.67e-2)" "unprognostic (7.97e-2)" "unprognostic (8.20e-3)" "unprognostic (1.20e-2)" "unprognostic (7.60e-2)" "unprognostic (2.33e-2)" "unprognostic (1.15e-2)" "unprognostic (1.83e-1)" "unprognostic (1.24e-2)" "unprognostic (3.05e-1)" "unprognostic (1.57e-1)" "unprognostic (4.89e-2)" "unprognostic (5.49e-2)" ZNF846 ENSG00000196605 "Zinc finger protein 846" Q147U1 19 9751993-9793180 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 202.4;Late primary spermatocytes: 492.4;Microglia: 165.4" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 209.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "HPA034617, HPA034618" Approved Approved "Actin filaments" NA NA "Cluster 18: Non-specific - Translation" "Cluster 21: Testis - Mixed function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 4: Non-specific - Transcription" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 1 "Actin filaments" "HPA034617: , HPA034618: " "unprognostic (7.59e-3)" "unprognostic (1.51e-1)" "unprognostic (2.41e-1)" "unprognostic (1.12e-1)" "unprognostic (2.52e-1)" "unprognostic (4.29e-2)" "unprognostic (2.20e-1)" "unprognostic (2.60e-1)" "potential prognostic favorable (2.71e-5)" "potential prognostic unfavorable (4.77e-4)" "unprognostic (1.01e-2)" "unprognostic (5.37e-2)" "unprognostic (1.09e-1)" "unprognostic (8.72e-2)" "unprognostic (1.85e-1)" "unprognostic (8.53e-2)" "unprognostic (2.28e-1)" "unprognostic (3.14e-1)" "unprognostic (9.93e-2)" "unprognostic (2.08e-2)" "unprognostic (2.40e-2)" "unprognostic (2.87e-1)" "unprognostic (8.11e-2)" "unprognostic (4.72e-2)" "potential prognostic favorable (6.22e-4)" "unprognostic (3.27e-2)" "unprognostic (2.08e-1)" "unprognostic (2.94e-1)" "unprognostic (1.17e-1)" "unprognostic (2.71e-3)" "potential prognostic unfavorable (6.77e-4)" ZNF85 "HPF4, HTF1" ENSG00000105750 "Zinc finger protein 85" Q03923 19 20923222-20950697 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bergmann glia: 8.6;Brain excitatory neurons: 8.9;Distal convoluted tubule cells: 17.8;Late primary spermatocytes: 12.4;Loop of henle epithelial cells: 11.9;Microglia: 19.2;Oligodendrocyte progenitor cells: 16.6;Oligodendrocytes: 10.7;Oocytes: 9.2;Papillary tip epithelial cells: 8.2;Podocytes: 10.8;Renal collecting duct intercalated cells: 15.4;Renal collecting duct principal cells: 14.6;Renal connecting tubule cells: 13.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" HPA044760 Approved Supported Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 39: Testis - Nuclear processes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 102: Non-specific - Mixed function" Nucleoplasm "HPA044760: " "unprognostic (3.57e-2)" "unprognostic (6.89e-2)" "unprognostic (1.04e-1)" "unprognostic (9.95e-2)" "unprognostic (1.52e-1)" "unprognostic (2.56e-2)" "unprognostic (1.74e-2)" "unprognostic (4.08e-2)" "unprognostic (1.70e-1)" "unprognostic (7.51e-2)" "unprognostic (1.42e-2)" "unprognostic (1.41e-1)" "unprognostic (2.97e-1)" "unprognostic (5.91e-2)" "unprognostic (3.36e-3)" "unprognostic (2.77e-1)" "unprognostic (4.39e-2)" "unprognostic (1.48e-2)" "unprognostic (1.59e-1)" "unprognostic (2.54e-2)" "potential prognostic unfavorable (3.30e-4)" "unprognostic (2.39e-1)" "potential prognostic unfavorable (5.27e-4)" "unprognostic (1.53e-1)" "unprognostic (1.87e-1)" "unprognostic (1.06e-1)" "potential prognostic unfavorable (5.47e-5)" "unprognostic (1.47e-1)" "unprognostic (2.20e-1)" "unprognostic (6.20e-2)" "potential prognostic unfavorable (9.25e-4)" ZNF850 ZNF850P ENSG00000267041 "Zinc finger protein 850" A8MQ14 19 36714383-36772825 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 96.8;Epicardial cells: 68.2;Erythrocyte progenitors: 51.5;Megakaryocyte progenitors: 31.6;Megakaryocyte-Erythroid progenitors: 40.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA029299 Uncertain Approved Nucleoplasm NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 15: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" Nucleoplasm "HPA029299: " "unprognostic (1.13e-1)" "unprognostic (1.79e-1)" "unprognostic (5.19e-2)" "unprognostic (3.45e-3)" "unprognostic (1.21e-1)" "unprognostic (1.44e-2)" "unprognostic (1.03e-1)" "unprognostic (1.56e-2)" "unprognostic (1.86e-1)" "unprognostic (5.95e-2)" "unprognostic (4.55e-1)" "unprognostic (6.55e-2)" "unprognostic (4.78e-2)" "unprognostic (2.50e-1)" "unprognostic (3.93e-2)" "unprognostic (1.86e-1)" "unprognostic (3.59e-1)" "unprognostic (1.09e-3)" "unprognostic (9.16e-3)" "unprognostic (3.65e-2)" "unprognostic (8.32e-2)" "unprognostic (2.49e-1)" "unprognostic (4.18e-2)" ZNF852 ENSG00000178917 "Zinc finger protein 852" Q6ZMS4 3 44494847-44510636 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 9.7;Bergmann glia: 14.5;Brain excitatory neurons: 12.8;Brain inhibitory neurons: 12.1;Choroid plexus epithelial cells: 14.1;Distal convoluted tubule cells: 10.3;Ependymal cells: 9.1;Loop of henle epithelial cells: 6.8;Microglia: 9.6;Oligodendrocyte progenitor cells: 14.9;Oligodendrocytes: 13.1;Other brain neurons: 11.4;Podocytes: 7.7;Proximal tubule cells: 8.3;Renal collecting duct intercalated cells: 7.9;Renal collecting duct principal cells: 6.5;Renal connecting tubule cells: 7.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA048312, HPA071850" Uncertain Approved Cytosol NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 98: Neurons - Neurotransmission & signaling" Cytosol "HPA048312: , HPA071850: " "unprognostic (1.13e-1)" "unprognostic (8.11e-2)" "unprognostic (1.50e-1)" "unprognostic (7.59e-2)" "unprognostic (1.43e-2)" "unprognostic (1.38e-3)" "unprognostic (4.57e-2)" "unprognostic (1.20e-1)" "unprognostic (5.79e-2)" "unprognostic (1.79e-1)" "unprognostic (2.23e-1)" "unprognostic (1.03e-1)" "unprognostic (9.08e-2)" "validated prognostic favorable (1.05e-5)" "validated prognostic favorable (8.99e-4)" "unprognostic (1.20e-1)" "unprognostic (4.16e-1)" "unprognostic (2.70e-2)" ZNF853 DKFZp434J1015 ENSG00000236609 "Zinc finger protein 853" P0CG23 7 6615610-6624290 "Predicted intracellular proteins, Transcription factors" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fallopian tube ciliated cells: 12.2;Müller glia: 12.7;Respiratory ciliated cells: 11.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 26.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 14.0" "Skeletal muscle - Skeletal myocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA067690 Approved Approved Nucleoli NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 11: Muller glia cells - Retinal homeostasis" Nucleoli "HPA067690: " "potential prognostic favorable (3.26e-4)" "validated prognostic favorable (3.57e-4)" "validated prognostic favorable (8.27e-4)" "unprognostic (2.74e-2)" "unprognostic (2.12e-2)" "unprognostic (7.23e-2)" "unprognostic (1.71e-1)" "unprognostic (4.48e-2)" "unprognostic (4.18e-1)" "unprognostic (1.98e-3)" "unprognostic (5.26e-3)" "unprognostic (1.82e-2)" "unprognostic (4.38e-2)" "unprognostic (6.19e-2)" "unprognostic (1.29e-1)" "unprognostic (7.49e-2)" "unprognostic (4.61e-2)" "unprognostic (9.42e-2)" "unprognostic (2.57e-2)" "potential prognostic favorable (9.45e-4)" "unprognostic (4.03e-2)" "unprognostic (1.89e-1)" "unprognostic (1.52e-1)" "unprognostic (3.72e-3)" "unprognostic (8.49e-3)" "unprognostic (9.94e-3)" "unprognostic (2.21e-2)" "unprognostic (1.90e-3)" "unprognostic (5.55e-2)" ZNF860 ENSG00000197385 "Zinc finger protein 860" A6NHJ4 3 31981750-31991723 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 3.9" "Cell type enhanced" "Detected in many" "B-cells: 30.9;Corticotrophs: 32.0;Esophageal apical cells: 22.5;Müller glia: 17.7;Pituitary stem cells: 27.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 49 "memory B-cell: 7.0;naive B-cell: 5.3" "Lineage enriched" "Detected in single" 56 "B-cells: 7.0" "Low cancer specificity" "Detected in many" "Testis - Sertoli cells" HPA063386 Uncertain Approved "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 22: Epididymis - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 2 "Nucleoli, Nucleoli rim" Nucleoplasm "HPA063386: " "unprognostic (5.02e-2)" "unprognostic (5.54e-2)" "unprognostic (9.04e-2)" "unprognostic (2.80e-2)" "unprognostic (7.27e-3)" "potential prognostic unfavorable (2.78e-4)" "potential prognostic favorable (3.33e-4)" "unprognostic (1.94e-1)" "unprognostic (1.77e-2)" "unprognostic (4.20e-2)" "unprognostic (5.17e-3)" "unprognostic (4.07e-2)" "unprognostic (6.07e-2)" "unprognostic (1.93e-1)" "unprognostic (6.04e-3)" "unprognostic (2.71e-2)" "unprognostic (6.08e-2)" "unprognostic (6.32e-2)" "unprognostic (1.76e-1)" "unprognostic (2.30e-1)" "unprognostic (4.26e-2)" ZNF862 ENSG00000106479 "Zinc finger protein 862" O60290 7 149838375-149867479 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" HPA024154 Uncertain Approved Mitochondria NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 64: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 39: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" Mitochondria "HPA024154: " "unprognostic (2.06e-3)" "unprognostic (3.40e-1)" "unprognostic (7.71e-2)" "unprognostic (1.42e-1)" "unprognostic (8.18e-3)" "unprognostic (1.60e-2)" "unprognostic (1.41e-1)" "unprognostic (3.96e-3)" "potential prognostic favorable (6.69e-4)" "unprognostic (4.40e-2)" "unprognostic (1.22e-1)" "potential prognostic favorable (5.08e-4)" "potential prognostic favorable (1.15e-4)" "unprognostic (2.08e-2)" "unprognostic (1.94e-2)" "unprognostic (1.80e-2)" "unprognostic (4.62e-2)" "unprognostic (1.39e-1)" "unprognostic (4.74e-2)" "unprognostic (1.30e-2)" "unprognostic (1.78e-1)" "unprognostic (3.86e-2)" "unprognostic (4.12e-2)" "unprognostic (2.45e-2)" "unprognostic (4.02e-1)" "unprognostic (1.64e-1)" "unprognostic (4.43e-2)" "unprognostic (1.04e-1)" "unprognostic (1.72e-1)" "unprognostic (1.22e-3)" "unprognostic (9.51e-3)" ZNF865 ENSG00000261221 "Zinc finger protein 865" P0CJ78 19 55605647-55617269 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 35.6" "Cell type enriched" "Detected in many" 6 "Late spermatids: 155.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA068079 Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 24: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 3 Nucleoli Nucleoplasm "HPA068079: " "unprognostic (2.79e-3)" "unprognostic (1.44e-2)" "unprognostic (3.84e-2)" "unprognostic (2.08e-1)" "unprognostic (2.95e-3)" "unprognostic (9.42e-2)" "unprognostic (2.13e-1)" "unprognostic (7.76e-2)" "unprognostic (2.48e-1)" "unprognostic (1.47e-1)" "unprognostic (2.08e-2)" "unprognostic (7.47e-2)" "potential prognostic unfavorable (1.50e-6)" "unprognostic (2.37e-2)" "unprognostic (1.87e-3)" "unprognostic (8.59e-2)" "unprognostic (2.17e-1)" "unprognostic (1.92e-1)" "unprognostic (7.60e-2)" "unprognostic (6.46e-2)" "unprognostic (6.83e-2)" "unprognostic (3.39e-2)" "unprognostic (6.87e-2)" "unprognostic (3.59e-1)" "unprognostic (1.89e-3)" "unprognostic (1.02e-1)" "unprognostic (5.28e-2)" "unprognostic (1.00e-1)" "unprognostic (6.67e-2)" "unprognostic (1.79e-1)" ZNF875 HKR1 ENSG00000181666 "Zinc finger protein 875" P10072 19 37312837-37369365 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 130.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 321.7;Choroid plexus epithelial cells: 156.8;Cone photoreceptor cells: 217.4;Rod photoreceptor cells: 240.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Prostate - Prostate glandular cells, Testis - Sertoli cells" "HPA036126, HPA044855" Approved Approved Nucleoplasm,Mitochondria No No "Cluster 14: Non-specific - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 48: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" "Nucleoplasm, Mitochondria" "HPA036126: , HPA044855: " "unprognostic (1.92e-2)" "unprognostic (1.04e-1)" "unprognostic (2.40e-2)" "unprognostic (2.27e-1)" "unprognostic (1.12e-1)" "unprognostic (1.21e-1)" "unprognostic (3.01e-1)" "unprognostic (3.68e-3)" "unprognostic (2.79e-1)" "unprognostic (1.57e-1)" "unprognostic (3.37e-3)" "potential prognostic favorable (8.48e-5)" "unprognostic (1.83e-1)" "unprognostic (9.85e-2)" "unprognostic (5.46e-2)" "unprognostic (8.32e-2)" "unprognostic (4.03e-2)" "unprognostic (3.23e-2)" "unprognostic (2.82e-1)" "unprognostic (6.16e-3)" "unprognostic (3.61e-2)" "unprognostic (1.09e-2)" "unprognostic (3.70e-2)" "unprognostic (2.37e-3)" "potential prognostic unfavorable (3.08e-4)" "unprognostic (5.78e-2)" "unprognostic (2.66e-1)" "unprognostic (6.32e-2)" "unprognostic (3.61e-2)" ZNF878 ENSG00000257446 "Zinc finger protein 878" C9JN71 19 12043805-12052961 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "Testicular Germ Cell Tumor (TCGA): 5.2" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Minor Salivary Gland - Minor salivary glandular cells" HPA052735 Uncertain Approved Nucleoplasm,Nucleoli NA NA "Cluster 44: Bone marrow - Nuclear processes" "Cluster 25: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 82: Dendritic cells - Antigen presentation" Nucleoplasm Nucleoli "HPA052735: " "unprognostic (2.50e-1)" "unprognostic (4.69e-3)" "unprognostic (8.95e-2)" "unprognostic (1.88e-1)" "unprognostic (6.52e-2)" ZNF879 DKFZp686E2433 ENSG00000234284 "Zinc finger protein 879" B4DU55 5 179023804-179035064 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 14.4;Early primary spermatocytes: 11.8;Late primary spermatocytes: 13.0;Oocytes: 13.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068608 Uncertain Approved Nucleoplasm NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" Nucleoplasm "HPA068608: " "unprognostic (3.37e-2)" "unprognostic (8.28e-3)" "unprognostic (2.64e-1)" "unprognostic (1.24e-1)" "unprognostic (1.26e-3)" "unprognostic (1.80e-1)" "unprognostic (2.93e-1)" "potential prognostic favorable (3.54e-4)" "unprognostic (3.07e-2)" "validated prognostic favorable (1.40e-5)" "validated prognostic favorable (1.62e-4)" "unprognostic (2.23e-1)" "potential prognostic favorable (7.15e-5)" "unprognostic (5.26e-2)" "unprognostic (1.55e-1)" "unprognostic (2.78e-1)" "unprognostic (4.02e-1)" "unprognostic (1.57e-3)" "unprognostic (1.01e-3)" "unprognostic (5.20e-2)" "unprognostic (2.04e-1)" "unprognostic (5.75e-2)" "unprognostic (1.91e-2)" "unprognostic (1.77e-1)" "unprognostic (1.38e-1)" "unprognostic (2.38e-1)" "unprognostic (1.48e-2)" ZNF880 ENSG00000221923 "Zinc finger protein 880" Q6PDB4 19 52369917-52385795 "Predicted intracellular proteins, Transcription factors" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA077316 Approved "Nucleoplasm,Nucleoli fibrillar center,Intermediate filaments" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" "Nucleoli fibrillar center" "Nucleoplasm, Intermediate filaments" "HPA077316: " "unprognostic (2.11e-1)" "unprognostic (1.54e-2)" "unprognostic (1.58e-1)" "unprognostic (9.35e-3)" "unprognostic (1.33e-1)" "unprognostic (3.04e-3)" "unprognostic (1.83e-1)" "unprognostic (8.27e-2)" "unprognostic (3.02e-2)" "unprognostic (4.92e-2)" "potential prognostic favorable (1.33e-5)" "unprognostic (2.26e-2)" "unprognostic (4.65e-3)" "unprognostic (1.80e-1)" "unprognostic (1.26e-1)" "unprognostic (1.20e-1)" "unprognostic (2.90e-2)" "unprognostic (1.54e-1)" "unprognostic (2.66e-1)" "unprognostic (1.40e-2)" "unprognostic (1.33e-1)" "unprognostic (6.52e-2)" "unprognostic (3.28e-2)" "unprognostic (1.10e-1)" "unprognostic (1.14e-1)" "unprognostic (8.82e-2)" "unprognostic (3.36e-2)" "unprognostic (5.75e-2)" "unprognostic (4.71e-1)" "unprognostic (3.56e-1)" "unprognostic (2.48e-2)" ZNF883 ENSG00000228623 "Zinc finger protein 883" P0CG24 9 112988129-113012192 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 7.7" "Cell type enhanced" "Detected in some" "Astrocytes: 42.4;Bergmann glia: 15.9;Brain excitatory neurons: 33.7;Brain inhibitory neurons: 67.7;Ependymal cells: 12.6;Oligodendrocyte progenitor cells: 59.1;Oligodendrocytes: 33.0;Other brain neurons: 17.6" "Low cell type specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 9: Non-specific - Receptor signaling" "Cluster 4: Non-specific - Transcription" "Cluster 35: Neurons - Synaptic function & neurogenesis" 1 ZNF888 ENSG00000213793 "Zinc finger protein 888" P0CJ79 19 52904415-52923470 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 29.2;Endometrial ciliated cells: 46.7;Endometrial glandular cells: 50.4;Endometrial luminal cells: 31.7;Prostatic hillock cells: 44.8;Urothelial cells: 38.2" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 11.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 4: Non-specific - Transcription" "Cluster 51: Secretory epithelial cells - Mixed function" 1 "potential prognostic favorable (4.50e-5)" "potential prognostic unfavorable (3.42e-4)" "unprognostic (8.28e-2)" "unprognostic (5.68e-2)" "unprognostic (1.87e-1)" "unprognostic (3.94e-2)" "unprognostic (1.93e-2)" "unprognostic (1.51e-1)" "unprognostic (1.51e-1)" "unprognostic (1.72e-2)" "unprognostic (1.08e-1)" "unprognostic (1.60e-2)" "unprognostic (1.02e-3)" "unprognostic (2.70e-2)" "unprognostic (8.69e-2)" "unprognostic (3.42e-2)" "unprognostic (8.50e-2)" "unprognostic (1.80e-3)" "unprognostic (5.04e-1)" "unprognostic (2.17e-1)" "unprognostic (2.81e-2)" "unprognostic (6.19e-2)" "unprognostic (4.85e-3)" "potential prognostic unfavorable (7.30e-4)" "unprognostic (1.14e-1)" "unprognostic (1.55e-1)" "unprognostic (1.97e-1)" "unprognostic (2.16e-1)" ZNF891 ENSG00000214029 "Zinc finger protein 891" A8MT65 12 133104779-133130274 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 69.1;Epicardial cells: 72.8;Lactotrophs: 62.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040301 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 24: Non-specific - Transcription" "Cluster 47: Testis - Mixed function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 61: BICR 18 - Protein kinases" "Cluster 7: Non-specific - Transcription" Nucleoplasm Vesicles "HPA040301: " "unprognostic (8.00e-2)" "unprognostic (1.23e-1)" "unprognostic (5.82e-2)" "unprognostic (4.64e-2)" "unprognostic (1.93e-1)" "unprognostic (9.07e-3)" "unprognostic (7.91e-2)" "unprognostic (8.78e-2)" "unprognostic (9.05e-2)" "unprognostic (3.24e-3)" "unprognostic (2.99e-2)" "unprognostic (8.03e-2)" "unprognostic (2.56e-1)" "unprognostic (6.12e-2)" "unprognostic (1.01e-1)" "unprognostic (5.70e-3)" "unprognostic (1.75e-1)" "unprognostic (1.02e-3)" "unprognostic (4.09e-3)" "unprognostic (6.59e-3)" "unprognostic (1.13e-2)" "unprognostic (5.38e-2)" "unprognostic (1.41e-1)" "unprognostic (2.49e-1)" "unprognostic (1.86e-2)" "unprognostic (5.83e-2)" ZNF90 HTF9 ENSG00000213988 "Zinc finger protein 90" Q03938 19 20077994-20127076 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Loop of henle epithelial cells: 39.9;Papillary tip epithelial cells: 76.2;Pituicytes/FSCs: 34.4;Renal collecting duct principal cells: 39.1;Renal connecting tubule cells: 29.5" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 21.3" "Cancer enriched" "Detected in some" 12 "Testicular Germ Cell Tumor (TCGA): 22.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "testis cancer: 9.6" HPA003227 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 49: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" Nucleoplasm "Golgi apparatus" "HPA003227: " "potential prognostic favorable (4.38e-5)" "unprognostic (8.72e-2)" "unprognostic (1.02e-2)" "unprognostic (8.07e-2)" "unprognostic (2.98e-3)" "unprognostic (3.94e-2)" "unprognostic (8.16e-2)" "unprognostic (1.90e-2)" "unprognostic (3.02e-2)" "unprognostic (2.32e-1)" "unprognostic (9.71e-2)" "unprognostic (9.55e-2)" "unprognostic (3.38e-2)" ZNF91 "HPF7, HTF10" ENSG00000167232 "Zinc finger protein 91" Q05481 19 23304991-23395471 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 426.7;Late spermatids: 677.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 1 "unprognostic (2.26e-2)" "unprognostic (8.93e-2)" "unprognostic (7.15e-2)" "unprognostic (8.11e-3)" "unprognostic (3.13e-2)" "unprognostic (4.82e-2)" "unprognostic (1.79e-1)" "unprognostic (8.69e-3)" "unprognostic (3.58e-2)" "unprognostic (1.86e-3)" "validated prognostic favorable (5.22e-4)" "validated prognostic favorable (1.40e-5)" "unprognostic (3.76e-2)" "unprognostic (4.80e-2)" "unprognostic (3.38e-1)" "unprognostic (1.25e-2)" "unprognostic (2.37e-1)" "unprognostic (1.11e-1)" "unprognostic (2.08e-1)" "unprognostic (2.97e-2)" "unprognostic (2.68e-1)" "unprognostic (1.25e-1)" "unprognostic (7.29e-3)" "unprognostic (7.74e-2)" "potential prognostic favorable (3.35e-4)" "unprognostic (2.04e-2)" "unprognostic (1.23e-2)" "unprognostic (5.29e-2)" "unprognostic (1.55e-1)" "unprognostic (1.45e-1)" "unprognostic (8.51e-2)" ZNF92 "HPF12, TF12" ENSG00000146757 "Zinc finger protein 92" Q03936 7 65373799-65401136 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "B-cells: 66.3;Esophageal apical cells: 92.8;Innate lymphoid cells: 59.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Testis - Spermatocytes" HPA003173 Approved Nucleoplasm NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 20: Non-specific - Transcription regulation" 6 Nucleoplasm "HPA003173: " "unprognostic (2.04e-2)" "unprognostic (2.74e-1)" "unprognostic (7.46e-2)" "potential prognostic unfavorable (1.77e-4)" "unprognostic (2.32e-2)" "unprognostic (3.62e-1)" "unprognostic (9.42e-2)" "unprognostic (4.22e-1)" "unprognostic (2.86e-1)" "unprognostic (1.01e-3)" "unprognostic (4.18e-3)" "unprognostic (4.88e-2)" "unprognostic (2.41e-1)" "unprognostic (1.05e-3)" "unprognostic (2.40e-2)" "unprognostic (1.27e-1)" "unprognostic (3.64e-2)" "unprognostic (2.54e-1)" "unprognostic (3.66e-2)" "unprognostic (1.49e-2)" "unprognostic (1.36e-1)" "unprognostic (2.15e-1)" "unprognostic (1.05e-2)" "unprognostic (1.15e-3)" "unprognostic (8.66e-2)" "unprognostic (8.52e-2)" "unprognostic (1.61e-2)" "unprognostic (6.60e-2)" "unprognostic (3.68e-1)" "unprognostic (1.79e-1)" "unprognostic (4.36e-2)" ZNF93 "FLJ12488, HPF34, TF34, ZNF505" ENSG00000184635 "Zinc finger protein 93" P35789 19 19900913-19963464 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oocytes: 124.3" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 31.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatic stellate cells, Testis - Spermatocytes" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 61: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 27: Non-specific - Cell proliferation" 1 "unprognostic (6.74e-3)" "unprognostic (4.47e-1)" "unprognostic (2.94e-1)" "unprognostic (1.11e-2)" "unprognostic (1.34e-1)" "unprognostic (7.68e-2)" "unprognostic (9.66e-2)" "unprognostic (2.83e-3)" "unprognostic (6.67e-2)" "potential prognostic unfavorable (1.27e-5)" "unprognostic (1.19e-1)" "unprognostic (2.68e-2)" "unprognostic (8.45e-2)" "unprognostic (3.44e-3)" "unprognostic (1.53e-1)" "unprognostic (9.98e-2)" "unprognostic (1.42e-3)" "unprognostic (1.03e-1)" "unprognostic (2.86e-1)" "unprognostic (8.51e-3)" "unprognostic (8.25e-2)" "unprognostic (1.07e-2)" "potential prognostic unfavorable (5.46e-4)" "unprognostic (8.77e-3)" "unprognostic (9.81e-2)" "unprognostic (1.80e-1)" "potential prognostic unfavorable (4.86e-5)" "unprognostic (1.30e-1)" "unprognostic (1.67e-1)" "unprognostic (1.57e-1)" "unprognostic (3.28e-1)" ZNF98 "F7175, ZNF739" ENSG00000197360 "Zinc finger protein 98" A6NK75 19 22391019-22532485 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "pancreas: 35.0" "Cell type enhanced" "Detected in many" "Astrocytes: 406.3;Distal convoluted tubule cells: 91.9;Early spermatids: 117.6;Granulosa cells: 197.9;Loop of henle epithelial cells: 74.6;Ovarian stromal cells: 86.4;Pancreatic acinar cells: 211.8;Renal connecting tubule cells: 150.4" "Group enriched" "Detected in many" 4 "astrocyte: 183.2;ependymal cell: 48.7" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 10.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Testis - Spermatocytes" NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 53: Neurons - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 28: Astrocytes - Homeostasis & neuron support" "unprognostic (2.12e-1)" "unprognostic (2.50e-2)" "potential prognostic favorable (1.49e-4)" "unprognostic (1.45e-1)" "unprognostic (7.29e-2)" "unprognostic (1.52e-2)" "unprognostic (3.90e-1)" "unprognostic (2.43e-1)" "unprognostic (6.00e-2)" ZNF99 "C19orf9, MGC24986" ENSG00000213973 "Zinc finger protein 99" A8MXY4 19 22752183-22784151 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "testis: 1.5" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 7.4;Distal convoluted tubule cells: 12.0;Early primary spermatocytes: 48.0;Epididymal clear cells: 12.2;Late primary spermatocytes: 10.5;Oligodendrocyte progenitor cells: 6.7;Renal collecting duct intercalated cells: 11.6;Renal collecting duct principal cells: 8.4;Renal connecting tubule cells: 9.4;Retinal bipolar cells: 6.8;Undifferentiated spermatogonia: 8.1" "Cell type enhanced" "Detected in many" "hippocampal CA4: 7.9" "Cancer enriched" "Detected in single" 8 "Testicular Germ Cell Tumor (TCGA): 4.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Spermatocytes" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 4: Non-specific - Transcription" "Cluster 3: Early primary spermatocytes - Early meiosis" "unprognostic (9.78e-3)" "unprognostic (2.96e-1)" ZNFX1 "FLJ11277, KIAA1404" ENSG00000124201 "Zinc finger NFX1-type containing 1" Q9P2E3 20 49237946-49278426 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Antiviral defense, Immunity, Innate immunity" RNA-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 311.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046629 Approved Approved Mitochondria No No "Cluster 35: Neutrophils - Protein binding" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 18 Mitochondria "HPA046629: " "unprognostic (1.87e-3)" "unprognostic (8.06e-2)" "unprognostic (3.18e-2)" "unprognostic (3.65e-2)" "unprognostic (2.49e-1)" "unprognostic (1.71e-1)" "unprognostic (1.12e-1)" "unprognostic (1.52e-1)" "unprognostic (3.59e-1)" "unprognostic (9.54e-3)" "potential prognostic favorable (1.50e-4)" "unprognostic (4.02e-3)" "unprognostic (1.89e-1)" "unprognostic (3.93e-2)" "potential prognostic favorable (3.12e-4)" "unprognostic (2.97e-1)" "unprognostic (2.68e-2)" "unprognostic (1.10e-2)" "unprognostic (1.48e-1)" "unprognostic (6.56e-2)" "unprognostic (5.68e-3)" "unprognostic (1.11e-2)" "unprognostic (5.03e-2)" "unprognostic (2.84e-1)" "unprognostic (1.71e-2)" "unprognostic (1.07e-2)" "unprognostic (4.12e-1)" "unprognostic (1.85e-1)" "unprognostic (1.17e-1)" "unprognostic (1.18e-1)" "unprognostic (4.94e-3)" ZNG1A CBWD1 ENSG00000172785 "Zn regulated GTPase metalloprotein activator 1A" Q9BRT8 9 120837-179147 "Disease related genes, Predicted intracellular proteins" "Chaperone, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 124.2;Syncytiotrophoblasts: 150.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA042759, HPA042813" Approved Approved "Plasma membrane" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 60: Prostate cancer - Unknown function" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 47 "Plasma membrane" "HPA042759: , HPA042813: " "unprognostic (4.16e-2)" "unprognostic (1.36e-2)" "unprognostic (7.40e-2)" "unprognostic (2.82e-2)" "unprognostic (5.24e-2)" "unprognostic (4.38e-2)" "unprognostic (5.22e-2)" "unprognostic (3.03e-2)" "unprognostic (1.60e-2)" "unprognostic (1.80e-1)" "potential prognostic favorable (2.37e-8)" "unprognostic (9.45e-3)" "unprognostic (1.84e-1)" "unprognostic (1.42e-1)" "unprognostic (2.59e-2)" "unprognostic (3.71e-1)" "unprognostic (6.93e-3)" "unprognostic (2.22e-1)" "unprognostic (2.50e-2)" "unprognostic (1.14e-2)" "unprognostic (1.08e-1)" "unprognostic (3.72e-1)" "unprognostic (1.27e-1)" "unprognostic (3.80e-2)" "unprognostic (5.16e-2)" "unprognostic (6.37e-2)" "unprognostic (1.82e-1)" "unprognostic (8.27e-2)" "unprognostic (2.74e-1)" "unprognostic (1.88e-1)" "unprognostic (1.08e-1)" ZNG1B CBWD2 ENSG00000136682 "Zn regulated GTPase metalloprotein activator 1B" Q8IUF1 2 113437691-113496204 "Essential proteins, Predicted intracellular proteins" "Chaperone, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "HPA042759, HPA042813" Approved Approved "Plasma membrane" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 26: Keratinocytes - Keratinization" 10 "Plasma membrane" "HPA042759: , HPA042813: " "unprognostic (2.02e-2)" "unprognostic (2.95e-1)" "unprognostic (3.93e-1)" "unprognostic (2.09e-2)" "unprognostic (2.76e-1)" "unprognostic (1.24e-1)" "unprognostic (7.60e-2)" "unprognostic (8.36e-2)" "unprognostic (3.46e-1)" "unprognostic (8.66e-2)" "potential prognostic favorable (1.11e-6)" "unprognostic (1.17e-3)" "unprognostic (3.55e-2)" "unprognostic (1.65e-2)" "unprognostic (2.05e-2)" "unprognostic (1.98e-1)" "unprognostic (3.73e-1)" "unprognostic (1.50e-1)" "unprognostic (1.44e-1)" "unprognostic (7.47e-2)" "unprognostic (1.59e-1)" "unprognostic (1.25e-2)" "unprognostic (1.43e-3)" "unprognostic (3.17e-1)" "unprognostic (2.03e-2)" "unprognostic (4.16e-2)" "unprognostic (8.08e-2)" "unprognostic (9.78e-3)" "unprognostic (2.19e-1)" "unprognostic (2.15e-1)" "unprognostic (8.63e-2)" ZNG1C "bA561O23.1, CBWD3" ENSG00000196873 "Zn regulated GTPase metalloprotein activator 1C" Q5JTY5 9 68232003-68300035 "Predicted intracellular proteins" "Chaperone, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 30.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells" "HPA042759, HPA042813" Uncertain Approved "Plasma membrane" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 70: Non-specific - Protein processing" "Cluster 37: Neurons - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 15: Non-specific - Protein processing" 29 "Plasma membrane" "HPA042759: , HPA042813: " "unprognostic (2.97e-2)" "unprognostic (2.81e-1)" "unprognostic (9.09e-2)" "unprognostic (2.82e-2)" "unprognostic (3.18e-1)" "unprognostic (1.53e-2)" "unprognostic (4.71e-2)" "unprognostic (7.54e-3)" "potential prognostic unfavorable (8.17e-4)" "unprognostic (2.82e-1)" "potential prognostic favorable (6.29e-5)" "unprognostic (4.53e-2)" "unprognostic (4.81e-2)" "unprognostic (4.81e-2)" "unprognostic (8.95e-2)" "unprognostic (4.55e-1)" "unprognostic (6.76e-2)" "unprognostic (8.41e-2)" "potential prognostic favorable (4.91e-4)" "unprognostic (1.09e-2)" "unprognostic (1.60e-2)" "unprognostic (3.83e-1)" "unprognostic (3.68e-2)" "unprognostic (2.34e-2)" "unprognostic (1.01e-3)" "unprognostic (2.82e-1)" "unprognostic (1.53e-1)" "unprognostic (6.76e-2)" "unprognostic (7.47e-2)" "unprognostic (2.20e-2)" "unprognostic (1.17e-1)" ZNG1E CBWD5 ENSG00000147996 "Zn regulated GTPase metalloprotein activator 1E" Q5RIA9 9 65668805-65734041 "Predicted intracellular proteins" "Chaperone, Hydrolase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 125.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "HPA042759, HPA042813" Approved Approved "Plasma membrane" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 55: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 35: Neurons - Synaptic function & neurogenesis" "Plasma membrane" "HPA042759: , HPA042813: " "unprognostic (3.12e-3)" "unprognostic (7.83e-2)" "unprognostic (4.25e-1)" "unprognostic (7.03e-3)" "unprognostic (2.77e-2)" "unprognostic (1.16e-1)" "unprognostic (2.79e-1)" "unprognostic (1.60e-3)" "potential prognostic unfavorable (4.49e-4)" "unprognostic (4.26e-1)" "unprognostic (1.98e-2)" "unprognostic (8.84e-2)" "unprognostic (5.48e-2)" "unprognostic (3.82e-3)" "unprognostic (1.22e-1)" "unprognostic (1.67e-2)" "unprognostic (4.56e-2)" "unprognostic (1.38e-1)" "unprognostic (9.96e-2)" "unprognostic (6.01e-2)" "unprognostic (2.67e-2)" "unprognostic (6.46e-2)" "unprognostic (8.84e-3)" "unprognostic (2.22e-1)" "unprognostic (1.80e-2)" "unprognostic (5.03e-2)" "unprognostic (7.05e-2)" "unprognostic (1.21e-1)" "unprognostic (2.82e-1)" "unprognostic (1.80e-1)" "unprognostic (1.40e-1)" ZNG1F "CBWD6, CBWD7" ENSG00000215126 "Zn regulated GTPase metalloprotein activator 1F" Q4V339 9 41131306-41199261 "Predicted intracellular proteins" "Chaperone, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late spermatids: 41.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "HPA042759, HPA042813" Approved Approved "Plasma membrane" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 70: Non-specific - Protein processing" "Cluster 36: Choroid plexus - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 15: Non-specific - Protein processing" 1 "Plasma membrane" "HPA042759: , HPA042813: " "unprognostic (2.13e-2)" "unprognostic (1.37e-1)" "potential prognostic favorable (6.59e-4)" "unprognostic (1.98e-1)" "unprognostic (2.56e-1)" "unprognostic (3.74e-2)" "unprognostic (6.62e-2)" "unprognostic (5.49e-2)" "unprognostic (8.42e-2)" "unprognostic (8.27e-2)" "unprognostic (2.85e-1)" "unprognostic (2.61e-2)" "unprognostic (2.10e-1)" "unprognostic (1.64e-2)" "unprognostic (1.24e-2)" "unprognostic (3.31e-3)" "unprognostic (1.79e-1)" "unprognostic (6.05e-2)" ZNHIT1 "CG1I, H_DJ0747G18.14, ZNFN4A1" ENSG00000106400 "Zinc finger HIT-type containing 1" O43257 7 101218165-101224190 "Predicted intracellular proteins" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 988.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019043 Uncertain Approved Nucleoplasm NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 27: Non-specific - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 93: Hepatocytes - Bile production & excretion" 53 Nucleoplasm "HPA019043: " "unprognostic (1.08e-1)" "unprognostic (2.28e-1)" "unprognostic (2.79e-2)" "unprognostic (7.28e-2)" "unprognostic (1.36e-1)" "unprognostic (2.51e-1)" "unprognostic (2.40e-2)" "unprognostic (2.84e-2)" "unprognostic (1.90e-2)" "unprognostic (4.64e-3)" "validated prognostic unfavorable (6.80e-4)" "validated prognostic unfavorable (6.15e-4)" "unprognostic (8.48e-3)" "unprognostic (8.10e-2)" "unprognostic (2.09e-1)" "unprognostic (3.05e-1)" "unprognostic (3.07e-2)" "unprognostic (2.54e-2)" "unprognostic (3.61e-1)" "unprognostic (2.13e-1)" "unprognostic (1.35e-1)" "unprognostic (5.88e-2)" "unprognostic (5.11e-1)" "unprognostic (7.60e-2)" "unprognostic (9.10e-2)" "unprognostic (1.44e-1)" "unprognostic (6.70e-2)" "unprognostic (1.42e-1)" "unprognostic (2.09e-1)" "unprognostic (1.92e-2)" "unprognostic (1.13e-1)" ZNHIT2 "C11orf5, FON" ENSG00000174276 "Zinc finger HIT-type containing 2" Q9UHR6 11 65116403-65117701 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 65.5" "Cell type enhanced" "Detected in many" "Early spermatids: 347.4;Late primary spermatocytes: 252.5;Late spermatids: 1220.4" "Cell type enhanced" "Detected in all" "ependymal cell: 15.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA058066 Uncertain NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 21: Non-specific - Metabolism" "Cluster 24: Non-specific - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 39 "HPA058066: " "unprognostic (9.42e-3)" "unprognostic (1.29e-1)" "unprognostic (9.93e-3)" "unprognostic (1.39e-1)" "unprognostic (2.10e-1)" "unprognostic (1.57e-1)" "unprognostic (5.98e-2)" "unprognostic (5.34e-3)" "unprognostic (5.55e-2)" "unprognostic (7.10e-2)" "unprognostic (1.70e-1)" "unprognostic (2.82e-1)" "unprognostic (1.55e-1)" "unprognostic (1.31e-3)" "unprognostic (2.39e-1)" "unprognostic (4.65e-2)" "unprognostic (7.25e-3)" "unprognostic (1.06e-1)" "unprognostic (2.42e-1)" "unprognostic (1.35e-2)" "unprognostic (2.71e-3)" "unprognostic (1.05e-2)" "unprognostic (1.11e-1)" "unprognostic (2.46e-1)" "unprognostic (5.65e-2)" "unprognostic (1.38e-1)" "unprognostic (2.98e-1)" "unprognostic (2.17e-2)" "unprognostic (1.04e-1)" "unprognostic (1.77e-2)" "unprognostic (4.90e-2)" ZNHIT3 "Hit1, TRIP3" ENSG00000273611 "Zinc finger HIT-type containing 3" Q15649 17 36486629-36499310 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Disease variant, Epilepsy, Intellectual disability, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 11.6;Bergmann glia: 15.6;Brain excitatory neurons: 19.8;Brain inhibitory neurons: 17.8;Choroid plexus epithelial cells: 8.5;Epicardial cells: 9.1;Loop of henle epithelial cells: 9.0;Microglia: 12.2;Oligodendrocyte progenitor cells: 14.3;Oligodendrocytes: 21.5;Other brain neurons: 21.8;Papillary tip epithelial cells: 8.4;Parietal cells: 8.8;Renal collecting duct principal cells: 9.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060019, HPA078211" Approved Approved Mitochondria NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 98: Neurons - Neurotransmission & signaling" 9 Mitochondria "HPA060019: , HPA078211: " "unprognostic (2.44e-2)" "unprognostic (2.26e-1)" "unprognostic (1.21e-2)" "potential prognostic favorable (1.13e-4)" "unprognostic (2.54e-1)" "unprognostic (4.08e-1)" "unprognostic (1.82e-2)" "unprognostic (6.49e-2)" "unprognostic (9.82e-2)" "unprognostic (3.37e-3)" "unprognostic (1.09e-1)" "unprognostic (1.33e-1)" "unprognostic (1.46e-3)" "potential prognostic unfavorable (1.14e-4)" "unprognostic (9.41e-3)" "unprognostic (7.57e-2)" "unprognostic (9.52e-3)" "unprognostic (3.68e-1)" "unprognostic (2.05e-1)" "unprognostic (2.40e-2)" "unprognostic (4.84e-1)" "potential prognostic favorable (2.36e-6)" "unprognostic (1.48e-1)" "unprognostic (1.86e-3)" "unprognostic (2.46e-3)" "unprognostic (1.25e-1)" "unprognostic (7.82e-2)" "unprognostic (2.08e-1)" ZNHIT6 "BCD1, C1orf181, FLJ20729, NY-BR-75" ENSG00000117174 "Zinc finger HIT-type containing 6" Q9NWK9 1 85649417-85708433 "Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018132, HPA050253" Approved Approved "Nuclear speckles,Vesicles" No No "Cluster 24: Non-specific - Transcription" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 7: Non-specific - Transcription" 20 "Nuclear speckles, Vesicles" "HPA018132: , HPA050253: " "unprognostic (5.20e-2)" "unprognostic (2.47e-1)" "unprognostic (3.52e-1)" "unprognostic (6.38e-2)" "unprognostic (1.89e-1)" "unprognostic (2.76e-3)" "unprognostic (4.60e-3)" "unprognostic (2.40e-1)" "unprognostic (1.58e-1)" "potential prognostic unfavorable (9.49e-5)" "unprognostic (1.72e-3)" "potential prognostic favorable (3.37e-4)" "unprognostic (5.59e-3)" "potential prognostic unfavorable (1.20e-5)" "unprognostic (8.02e-2)" "unprognostic (5.72e-2)" "unprognostic (3.38e-3)" "unprognostic (5.62e-2)" "unprognostic (3.64e-2)" "unprognostic (9.35e-2)" "unprognostic (3.44e-2)" "unprognostic (6.51e-3)" "unprognostic (5.68e-2)" "unprognostic (3.44e-2)" "unprognostic (2.37e-1)" "unprognostic (2.53e-1)" "unprognostic (1.01e-1)" "unprognostic (1.72e-1)" "unprognostic (1.66e-1)" "unprognostic (8.73e-2)" "unprognostic (2.60e-1)" ZNRD2 "p27, SSSCA1" ENSG00000173465 "Zinc ribbon domain containing 2" O60232 11 65570460-65573942 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 188.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039789, HPA064670" Uncertain Approved Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 24: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 100 Cytosol "HPA039789: , HPA064670: " "unprognostic (7.67e-2)" "unprognostic (6.52e-2)" "unprognostic (9.51e-2)" "unprognostic (1.61e-2)" "unprognostic (1.84e-1)" "unprognostic (5.30e-2)" "unprognostic (2.65e-1)" "unprognostic (2.83e-3)" "potential prognostic unfavorable (6.38e-5)" "potential prognostic favorable (2.88e-4)" "unprognostic (3.17e-2)" "unprognostic (1.19e-2)" "potential prognostic unfavorable (9.39e-4)" "unprognostic (1.06e-1)" "unprognostic (4.66e-3)" "unprognostic (1.50e-1)" "unprognostic (2.94e-1)" "unprognostic (6.19e-2)" "unprognostic (3.00e-1)" "unprognostic (1.84e-1)" "unprognostic (8.12e-2)" "unprognostic (5.01e-2)" "unprognostic (3.79e-2)" "unprognostic (1.17e-1)" "unprognostic (2.74e-1)" "unprognostic (3.14e-1)" "unprognostic (1.21e-1)" "unprognostic (2.18e-1)" "unprognostic (7.60e-2)" ZNRF1 "DKFZp434E229, FLJ14846, nin283" ENSG00000186187 "Zinc and ring finger 1" Q8ND25 16 74999024-75110994 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 484.8;Hematopoietic stem cells: 407.1;Mast cells: 240.0;Megakaryocyte-Erythroid progenitors: 269.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.4;T-reg: 2.5" "Group enriched" "Detected in many" 4 "granulocytes: 2.4;T-cells: 2.5" "Low cancer specificity" "Detected in all" "Skeletal muscle - Skeletal myocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027470 Approved Supported "Vesicles,Primary cilium tip,Primary cilium transition zone" NA NA "Cluster 68: Non-specific - Basic cellular processes" "Cluster 24: Neurons - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 28 Vesicles "Primary cilium tip, Primary cilium transition zone" "HPA027470: " "unprognostic (4.28e-2)" "unprognostic (2.05e-3)" "unprognostic (8.67e-2)" "unprognostic (2.66e-1)" "unprognostic (5.40e-2)" "unprognostic (5.45e-2)" "unprognostic (2.06e-1)" "potential prognostic favorable (4.38e-5)" "unprognostic (1.89e-1)" "unprognostic (1.22e-2)" "unprognostic (2.42e-1)" "unprognostic (3.10e-1)" "potential prognostic unfavorable (1.27e-4)" "unprognostic (1.12e-2)" "unprognostic (4.26e-2)" "unprognostic (7.52e-2)" "unprognostic (6.38e-2)" "unprognostic (1.14e-1)" "unprognostic (2.28e-1)" "unprognostic (6.01e-2)" "unprognostic (2.43e-1)" "unprognostic (1.61e-1)" "unprognostic (1.82e-2)" "unprognostic (1.54e-1)" "unprognostic (3.40e-1)" "unprognostic (6.58e-2)" "unprognostic (6.63e-2)" "unprognostic (4.90e-2)" "unprognostic (7.80e-2)" "unprognostic (6.18e-2)" "unprognostic (2.43e-2)" ZNRF2 RNF202 ENSG00000180233 "Zinc and ring finger 2" Q8NHG8 7 30284597-30367689 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglia: 410.2;Pituicytes/FSCs: 300.4" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 478.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 2.3" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072244 Approved Uncertain "Nucleoplasm,Nucleoli fibrillar center,Vesicles" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 67: Non-specific - Unknown function" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 15 "Nucleoplasm, Vesicles" "Nucleoli fibrillar center" "HPA072244: " "unprognostic (3.25e-2)" "unprognostic (7.41e-3)" "unprognostic (2.21e-2)" "unprognostic (8.64e-3)" "unprognostic (1.29e-2)" "unprognostic (2.13e-2)" "unprognostic (2.08e-2)" "unprognostic (1.60e-1)" "unprognostic (1.34e-1)" "unprognostic (5.56e-2)" "potential prognostic favorable (6.89e-8)" "unprognostic (5.33e-2)" "unprognostic (2.27e-1)" "unprognostic (3.45e-1)" "unprognostic (1.91e-1)" "unprognostic (7.57e-2)" "unprognostic (2.32e-1)" "unprognostic (3.69e-2)" "unprognostic (2.21e-1)" "unprognostic (1.44e-1)" "unprognostic (2.86e-2)" "unprognostic (7.53e-2)" "unprognostic (8.42e-2)" "unprognostic (8.72e-2)" "unprognostic (2.60e-2)" "unprognostic (3.42e-1)" "unprognostic (4.86e-2)" "unprognostic (1.08e-1)" "unprognostic (1.78e-1)" "unprognostic (5.79e-3)" "unprognostic (3.57e-2)" ZNRF3 "BK747E2.3, FLJ22057, KIAA1133, RNF203" ENSG00000183579 "Zinc and ring finger 3" Q9ULT6 22 28883572-29057488 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway, Wnt signaling pathway" "Developmental protein, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 630.8;Loop of henle epithelial cells: 400.2;Podocytes: 1195.5;Renal collecting duct intercalated cells: 306.2" "Cell type enhanced" "Detected in all" "astrocyte: 533.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Minor Salivary Gland - Smooth muscle cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Stomach - Chief cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036702, HPA036703" Uncertain Uncertain "Golgi apparatus" NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 32: Non-specific - Cell proliferation" "Cluster 57: Podocytes - Glomerular filtration" 13 "Golgi apparatus" "HPA036702: , HPA036703: " "unprognostic (3.52e-1)" "unprognostic (2.89e-1)" "unprognostic (1.61e-1)" "unprognostic (8.57e-2)" "unprognostic (2.90e-2)" "unprognostic (1.55e-2)" "unprognostic (1.75e-2)" "unprognostic (3.74e-1)" "unprognostic (1.05e-1)" "unprognostic (1.68e-1)" "potential prognostic favorable (1.80e-7)" "unprognostic (1.73e-3)" "unprognostic (9.79e-2)" "unprognostic (8.70e-2)" "unprognostic (1.50e-1)" "unprognostic (3.19e-3)" "unprognostic (5.07e-2)" "unprognostic (2.37e-1)" "potential prognostic favorable (1.94e-4)" "unprognostic (1.05e-1)" "unprognostic (1.51e-1)" "unprognostic (3.07e-1)" "unprognostic (3.21e-1)" "unprognostic (1.19e-1)" "unprognostic (1.79e-3)" "unprognostic (1.19e-1)" "unprognostic (1.97e-1)" "unprognostic (1.83e-1)" "unprognostic (3.92e-2)" "unprognostic (5.19e-3)" "potential prognostic favorable (8.35e-4)" ZNRF4 "RNF204, spzn, Ssrzf1" ENSG00000105428 "Zinc and ring finger 4" Q8WWF5 19 5455417-5456856 "Enzymes, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 455 "testis: 112.5" "Group enriched" "Detected in some" 210 "Early spermatids: 694.3;Late primary spermatocytes: 277.1;Late spermatids: 840.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 47: Leukemia - Hemostasis" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 8 ZP1 ZPB1 ENSG00000149506 "Zona pellucida glycoprotein 1" P60852 11 60867542-60875693 "Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Fertilization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 4 "Late spermatids: 138.5" "Group enriched" "Detected in some" 4 "fibroblast: 11.2;pericyte: 13.1" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 32 "plasmacytoid DC: 3.1" "Lineage enriched" "Detected in single" 32 "dendritic cells: 3.1" "Not detected" "Not detected" "Breast - Adipocytes (Breast), Prostate - Prostate glandular cells, Skin - Sebaceous gland cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Secreted in female reproductive system" Other NA NA "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" "unprognostic (3.14e-1)" ZP2 ZPA ENSG00000103310 "Zona pellucida glycoprotein 2" Q05996 16 21197450-21214510 "Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Fertilization Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "brain: 35.0" "Group enriched" "Detected in some" 10 "Brain excitatory neurons: 8.0;Enterocytes: 6.3;Oocytes: 23.0" "Cell type enriched" "Detected in single" 23 "upper rhombic lip: 17.1" "Not detected" "Not detected" "Region enriched" "Detected in single" 16 "cerebellum: 11.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA011296 Enhanced "Secreted in female reproductive system" Receptor NA NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 27: Breast cancer - Unknown function" "Cluster 2: Cerebellar granular cells - Neuronal signaling" "HPA011296: " ZP3 "ZP3-372, ZP3-424, ZP3A, ZP3B, ZPC" ENSG00000188372 "Zona pellucida glycoprotein 3" P21754 7 76397518-76442071 "Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Fertilization Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 19.1" "Cell type enriched" "Detected in many" 30 "Oocytes: 2910.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Myeloma: 42.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA054061, HPA071198" Supported "Secreted in female reproductive system" Receptor NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 33: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 41: Oocytes - Oogenesis" 4 "HPA054061: , HPA071198: " "unprognostic (1.14e-2)" "unprognostic (1.03e-1)" "unprognostic (1.40e-1)" "unprognostic (1.25e-1)" "unprognostic (6.16e-3)" "unprognostic (6.98e-2)" "potential prognostic unfavorable (1.30e-4)" "unprognostic (2.96e-2)" "unprognostic (3.70e-3)" "unprognostic (3.60e-3)" "validated prognostic unfavorable (6.74e-4)" "validated prognostic unfavorable (3.35e-4)" "unprognostic (5.38e-2)" "potential prognostic unfavorable (3.76e-4)" "unprognostic (9.64e-3)" "unprognostic (1.80e-2)" "unprognostic (4.88e-3)" "unprognostic (4.15e-2)" "unprognostic (1.05e-1)" "unprognostic (1.78e-1)" "unprognostic (1.10e-1)" "unprognostic (1.84e-3)" "unprognostic (1.36e-1)" "unprognostic (3.53e-2)" "unprognostic (2.96e-1)" "unprognostic (8.85e-2)" "unprognostic (1.97e-1)" "unprognostic (1.56e-1)" "unprognostic (7.49e-2)" "unprognostic (3.38e-1)" "unprognostic (1.97e-1)" ZP4 "ZP1B, ZPB, ZPB2" ENSG00000116996 "Zona pellucida glycoprotein 4" Q12836 1 237877864-237890922 "Predicted membrane proteins, Predicted secreted proteins" Fertilization Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 18 "ovary: 3.6" "Cell type enriched" "Detected in some" 53 "Oocytes: 92.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA008547 Enhanced "Secreted in female reproductive system" Receptor NA NA "Cluster 75: Ovary - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 41: Oocytes - Oogenesis" 1 "HPA008547: " ZPBP "SP38, ZPBP1" ENSG00000042813 "Zona pellucida binding protein" Q9BS86 7 49850421-50121329 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 31 "testis: 133.7" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 979.3;Early primary spermatocytes: 296.2;Early spermatids: 927.3;Late primary spermatocytes: 1733.7;Retinal bipolar cells: 795.2;Retinal ganglion cells: 170.0;Rod photoreceptor cells: 655.9" "Cell type enhanced" "Detected in many" "LAMP5-LHX6 and Chandelier: 55.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA058673 Enhanced "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 6: Leukemia - Signal transduction" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "HPA058673: " ZPBP2 "MGC41930, ZPBPL" ENSG00000186075 "Zona pellucida binding protein 2" Q6X784 17 39868202-39877896 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 100 "testis: 89.1" "Cell type enhanced" "Detected in some" "Early primary spermatocytes: 241.5;Early spermatids: 206.9;Late primary spermatocytes: 881.7;Late spermatids: 107.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 8 "lymphoma: 2.7" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA027997, HPA053070" Enhanced "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 9: Non-specific - Receptor signaling" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" "HPA027997: , HPA053070: " "unprognostic (8.82e-2)" ZPLD1 ENSG00000170044 "Zona pellucida like domain containing 1" Q8TCW7 3 102099244-102479841 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "gallbladder: 2.1;retina: 2.3" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 21.3;Breast secretory cells: 19.5;Early spermatids: 63.7;Endometrial glandular cells: 29.3;Epicardial cells: 47.8;Late primary spermatocytes: 70.1;Late spermatids: 44.0;Müller glia: 21.6;Pancreatic duct cells: 32.9;Papillary tip epithelial cells: 78.2;Renal collecting duct principal cells: 45.9;Renal connecting tubule cells: 29.5" "Cell type enhanced" "Detected in many" "leukocyte: 6.0" "Cancer enhanced" "Detected in some" "Kidney Renal Papillary Cell Carcinoma (TCGA): 3.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 8 "Rhabdoid: 39.2" "Colon - Colon enteroendocrine cells, Minor Salivary Gland - Minor salivary glandular cells" "Region enriched" "Detected in single" 7 "olfactory bulb: 2.8" "Not detected" "Not detected" HPA077519 Approved Nucleoplasm "Intracellular and membrane" "No annotated function" NA NA "Cluster 42: Retina - Visual perception" "Cluster 49: Hindbrain - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 51: Secretory epithelial cells - Mixed function" Nucleoplasm "HPA077519: " "unprognostic (2.89e-1)" "unprognostic (4.77e-2)" "unprognostic (1.48e-1)" "unprognostic (1.84e-2)" "unprognostic (3.19e-2)" "potential prognostic unfavorable (1.59e-4)" "unprognostic (2.19e-1)" ZPR1 ZNF259 ENSG00000109917 "ZPR1 zinc finger" O75312 11 116773799-116788039 "Disease related genes, Essential proteins, Predicted intracellular proteins" "Differentiation, mRNA processing, mRNA splicing" "Deafness, Dwarfism, Hypotrichosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 225.7;Late primary spermatocytes: 204.7;Late spermatids: 624.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022596, HPA030979" Uncertain Approved Vesicles NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 14: Neurons - Synaptic function" "Cluster 24: Non-specific - Unknown function" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 2 Vesicles "CAB022596: , HPA030979: " "unprognostic (2.29e-1)" "unprognostic (1.21e-3)" "unprognostic (3.89e-2)" "unprognostic (1.38e-1)" "unprognostic (9.17e-2)" "unprognostic (3.67e-1)" "unprognostic (2.33e-1)" "unprognostic (1.13e-2)" "potential prognostic unfavorable (3.03e-4)" "potential prognostic favorable (5.31e-4)" "unprognostic (4.46e-2)" "unprognostic (1.34e-1)" "potential prognostic unfavorable (1.73e-5)" "validated prognostic unfavorable (3.49e-4)" "validated prognostic unfavorable (2.20e-4)" "unprognostic (1.45e-1)" "unprognostic (1.23e-1)" "unprognostic (3.63e-1)" "unprognostic (2.06e-1)" "unprognostic (4.05e-3)" "unprognostic (1.02e-2)" "unprognostic (4.81e-2)" "unprognostic (3.83e-3)" "unprognostic (7.20e-2)" "unprognostic (3.89e-2)" "unprognostic (4.30e-1)" "unprognostic (2.34e-1)" "unprognostic (1.46e-2)" "unprognostic (2.07e-1)" ZRANB1 TRABID ENSG00000019995 "Zinc finger RANBP2-type containing 1" Q9UGI0 10 124942123-124988189 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway, Wnt signaling pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 220.1;Neutrophils: 276.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029239, HPA029240, HPA029241" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 16: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 345 Nucleoplasm Cytosol "HPA029239: , HPA029240: , HPA029241: " "unprognostic (7.29e-3)" "unprognostic (1.42e-1)" "unprognostic (2.95e-1)" "unprognostic (1.21e-2)" "unprognostic (9.32e-2)" "unprognostic (1.98e-2)" "unprognostic (2.51e-1)" "potential prognostic favorable (5.01e-4)" "unprognostic (1.78e-2)" "unprognostic (3.93e-2)" "potential prognostic favorable (6.93e-6)" "unprognostic (3.48e-3)" "unprognostic (1.12e-1)" "unprognostic (4.13e-2)" "unprognostic (4.47e-2)" "unprognostic (2.80e-1)" "unprognostic (1.54e-1)" "unprognostic (3.15e-1)" "unprognostic (3.73e-1)" "unprognostic (2.31e-2)" "unprognostic (6.46e-3)" "unprognostic (1.82e-1)" "unprognostic (3.66e-2)" "unprognostic (3.66e-2)" "unprognostic (4.01e-2)" "unprognostic (2.01e-2)" "unprognostic (2.70e-1)" "unprognostic (8.00e-2)" "unprognostic (1.40e-1)" "unprognostic (8.92e-2)" "unprognostic (1.46e-1)" ZRANB2 "ZIS, ZIS1, ZIS2, ZNF265" ENSG00000132485 "Zinc finger RANBP2-type containing 2" O95218 1 71063291-71081289 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Lactotrophs: 677.4;Somatotrophs: 666.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053960, HPA061949, HPA063298" Supported Enhanced Nucleoplasm NA Yes "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 9: Non-specific - Receptor signaling" "Cluster 37: Non-specific - mRNA processing" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 17 Nucleoplasm "HPA053960: , HPA061949: , HPA063298: " "unprognostic (4.32e-2)" "unprognostic (2.66e-2)" "unprognostic (2.02e-1)" "unprognostic (2.67e-1)" "unprognostic (1.25e-1)" "unprognostic (2.11e-1)" "unprognostic (4.49e-3)" "unprognostic (2.69e-1)" "unprognostic (4.40e-2)" "potential prognostic unfavorable (3.51e-5)" "unprognostic (2.91e-1)" "unprognostic (1.49e-1)" "unprognostic (1.30e-1)" "potential prognostic unfavorable (3.26e-6)" "unprognostic (1.23e-1)" "unprognostic (2.94e-1)" "unprognostic (8.50e-2)" "unprognostic (3.82e-2)" "unprognostic (4.72e-1)" "unprognostic (1.34e-1)" "unprognostic (5.46e-2)" "unprognostic (4.85e-2)" "unprognostic (3.45e-3)" "unprognostic (1.27e-2)" "potential prognostic favorable (9.99e-4)" "unprognostic (1.07e-1)" "unprognostic (2.06e-2)" "unprognostic (9.04e-3)" "unprognostic (5.37e-1)" "unprognostic (1.19e-1)" "unprognostic (1.28e-1)" ZRANB3 "AH2, DKFZP434B1727" ENSG00000121988 "Zinc finger RANBP2-type containing 3" Q5FWF4 2 135136916-135531218 "Cancer-related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "Endonuclease, Helicase, Hydrolase, Multifunctional enzyme, Nuclease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 386.9;Epicardial cells: 366.1;Myonuclei: 351.5;Sertoli cells: 263.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035234 Supported Nucleoplasm NA NA "Cluster 40: Non-specific - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 4 Nucleoplasm "HPA035234: " "unprognostic (8.66e-2)" "unprognostic (1.09e-2)" "unprognostic (1.57e-1)" "unprognostic (1.90e-2)" "unprognostic (2.95e-2)" "unprognostic (6.97e-2)" "unprognostic (6.27e-2)" "unprognostic (4.50e-2)" "unprognostic (3.94e-1)" "unprognostic (1.78e-1)" ZRSR2 "U2AF1-RS2, U2AF1L2, URP, ZC3H22" ENSG00000169249 "Zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2" Q15696 X 15790156-15830694 "Cancer-related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Cancer-related genes, Ciliopathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 181.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 36: Non-specific - mRNA processing" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 46 "unprognostic (1.68e-1)" "unprognostic (9.89e-3)" "unprognostic (2.40e-2)" "unprognostic (7.48e-2)" "unprognostic (4.38e-2)" "unprognostic (8.58e-2)" "unprognostic (1.13e-1)" "unprognostic (1.75e-1)" "unprognostic (4.33e-1)" "potential prognostic unfavorable (7.47e-4)" "unprognostic (2.09e-2)" "unprognostic (2.75e-2)" "unprognostic (2.85e-1)" "unprognostic (1.07e-3)" "unprognostic (1.82e-1)" "unprognostic (1.09e-2)" "unprognostic (5.55e-2)" "unprognostic (3.49e-2)" "unprognostic (1.33e-1)" "unprognostic (2.02e-2)" "unprognostic (5.12e-2)" "unprognostic (5.10e-2)" "unprognostic (1.40e-1)" "unprognostic (8.54e-2)" "unprognostic (3.40e-1)" "unprognostic (2.29e-1)" "unprognostic (1.95e-1)" "unprognostic (4.09e-2)" "unprognostic (1.61e-1)" "unprognostic (1.59e-1)" "unprognostic (7.60e-2)" ZSCAN1 "FLJ33779, ZNF915" ENSG00000152467 "Zinc finger and SCAN domain containing 1" Q8NBB4 19 58034025-58054631 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.0;pituitary gland: 15.5;testis: 8.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 29.9;Early spermatids: 43.3;Endometrial ciliated cells: 38.8;Ependymal cells: 28.8;Epididymal efferent duct ciliated cells: 48.3;Epididymal principal cells: 114.9;Fallopian tube ciliated cells: 43.4;Late primary spermatocytes: 57.7;Late spermatids: 74.0;Respiratory ciliated cells: 34.5" "Cell type enhanced" "Detected in many" "ependymal cell: 36.7" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 6.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 2.4" "Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary gland ductal cells, Prostate - Prostate glandular cells, Testis - Early spermatids" HPA007938 Uncertain Approved Nucleoplasm,Nucleoli NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 4: Non-specific - Transcription" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 3 Nucleoli Nucleoplasm "HPA007938: " "unprognostic (4.79e-3)" "unprognostic (2.41e-2)" "unprognostic (1.61e-1)" "unprognostic (2.24e-2)" "unprognostic (6.78e-3)" "unprognostic (2.36e-2)" "unprognostic (1.11e-2)" "unprognostic (8.20e-3)" "unprognostic (5.90e-2)" "unprognostic (5.34e-3)" "unprognostic (1.29e-1)" ZSCAN10 ZNF206 ENSG00000130182 "Zinc finger and SCAN domain containing 10" Q96SZ4 16 3088890-3099295 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 2.4;Epicardial cells: 2.3;Late spermatids: 1.1;Migrating cytotrophoblasts: 2.2" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 64 "Testicular Germ Cell Tumor (TCGA): 39.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "testis cancer: 5.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA076826 Approved Nucleoplasm,Centrosome NA NA "Cluster 9: Non-specific - Receptor signaling" "Cluster 34: Testis cancer - Unknown function" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 1 Nucleoplasm Centrosome "HPA076826: " "unprognostic (2.87e-2)" ZSCAN12 "dJ29K1.2, KIAA0426, ZFP96, ZNF29K1, ZNF305, ZNF96" ENSG00000158691 "Zinc finger and SCAN domain containing 12" O43309 6 28378955-28399747 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 46.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006637, HPA007018" Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 32: Basophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 2: Neurons - Nucleosome" "Cluster 28: Non-specific - Nuclear processes" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 20 Nucleoplasm "Nuclear bodies, Cytosol" "HPA006637: , HPA007018: " "unprognostic (4.00e-3)" "unprognostic (4.74e-2)" "unprognostic (2.61e-2)" "potential prognostic unfavorable (9.38e-4)" "unprognostic (2.91e-2)" "unprognostic (1.04e-1)" "unprognostic (9.03e-2)" "unprognostic (1.71e-1)" "unprognostic (1.31e-1)" "unprognostic (1.93e-2)" "potential prognostic favorable (2.61e-4)" "unprognostic (1.12e-3)" "unprognostic (1.76e-1)" "unprognostic (7.19e-2)" "unprognostic (3.50e-2)" "unprognostic (6.88e-3)" "unprognostic (2.02e-1)" "unprognostic (1.62e-1)" "unprognostic (2.37e-1)" "unprognostic (1.18e-1)" "unprognostic (8.10e-2)" "unprognostic (5.16e-2)" "unprognostic (4.07e-1)" "potential prognostic favorable (3.56e-5)" "unprognostic (1.24e-1)" "unprognostic (5.35e-2)" "unprognostic (8.83e-3)" "unprognostic (2.08e-1)" "unprognostic (8.79e-2)" "unprognostic (8.42e-2)" ZSCAN16 "dJ265C24.3, FLJ22191, ZNF392, ZNF435" ENSG00000196812 "Zinc finger and SCAN domain containing 16" Q9H4T2 6 28107689-28130082 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 24.6;Cardiomyocytes: 107.3;Oocytes: 41.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 69.2" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" HPA007290 Supported Approved Nucleoplasm NA NA "Cluster 41: Basophils - Unknown function" "Cluster 17: Intestine - Digestion" "Cluster 11: White matter - Signal transduction" "Cluster 28: Non-specific - Nuclear processes" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 9 Nucleoplasm "HPA007290: " "potential prognostic favorable (2.60e-4)" "unprognostic (1.54e-1)" "unprognostic (7.17e-2)" "unprognostic (1.28e-1)" "unprognostic (4.80e-2)" "unprognostic (2.16e-2)" "unprognostic (7.89e-2)" "unprognostic (5.12e-3)" "unprognostic (1.45e-2)" "unprognostic (7.36e-2)" "unprognostic (1.66e-2)" "unprognostic (9.36e-3)" "unprognostic (8.10e-3)" "unprognostic (2.03e-2)" "unprognostic (1.68e-1)" "unprognostic (1.09e-1)" "unprognostic (8.92e-2)" "unprognostic (2.85e-2)" "unprognostic (1.30e-1)" "potential prognostic favorable (2.12e-4)" "unprognostic (1.50e-1)" "unprognostic (1.33e-1)" "unprognostic (6.80e-2)" "unprognostic (2.04e-1)" "potential prognostic favorable (7.84e-7)" "unprognostic (1.96e-2)" "unprognostic (1.53e-2)" "unprognostic (4.77e-2)" "unprognostic (1.19e-1)" "unprognostic (6.18e-2)" "unprognostic (2.93e-1)" ZSCAN18 "FLJ12895, ZNF447" ENSG00000121413 "Zinc finger and SCAN domain containing 18" Q8TBC5 19 58083838-58118427 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells" "Low region specificity" "Detected in all" HPA024318 Supported Approved "Nucleoplasm,Primary cilium,Basal body,Cytosol" No No "Cluster 22: Eosinophils - Transcription" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 14: Neurons - Synaptic function" "Cluster 4: Non-specific - Transcription" "Cluster 94: Gonadal somatic cells - Mixed function" 15 Nucleoplasm "Primary cilium, Basal body, Cytosol" "HPA024318: " "unprognostic (1.44e-3)" "unprognostic (4.34e-2)" "unprognostic (5.95e-2)" "unprognostic (1.95e-1)" "unprognostic (1.76e-1)" "unprognostic (2.35e-1)" "unprognostic (3.45e-1)" "unprognostic (3.69e-1)" "unprognostic (6.37e-2)" "unprognostic (2.37e-1)" "validated prognostic favorable (1.64e-6)" "validated prognostic favorable (1.08e-7)" "potential prognostic favorable (1.52e-6)" "unprognostic (3.92e-2)" "unprognostic (2.56e-1)" "unprognostic (2.36e-2)" "unprognostic (3.22e-2)" "unprognostic (4.70e-2)" "unprognostic (1.64e-1)" "unprognostic (1.47e-1)" "unprognostic (2.06e-1)" "unprognostic (3.83e-3)" "unprognostic (2.95e-1)" "unprognostic (2.99e-1)" "unprognostic (3.28e-1)" "unprognostic (1.44e-1)" "unprognostic (4.62e-2)" "unprognostic (3.81e-3)" "unprognostic (3.51e-1)" "unprognostic (1.54e-1)" "unprognostic (6.38e-3)" ZSCAN2 "FLJ20595, ZFP29, ZNF854" ENSG00000176371 "Zinc finger and SCAN domain containing 2" Q7Z7L9 15 84600986-84627796 "Predicted intracellular proteins, Transcription factors" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 23.0;Cardiomyocytes: 30.3;Late primary spermatocytes: 25.4;Pancreatic acinar cells: 31.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007296, HPA024331" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 8: Pancreas - Proteolysis" "Cluster 25: Non-specific - Transcription" "Cluster 6: Leukemia - Signal transduction" "Cluster 51: Secretory epithelial cells - Mixed function" Nucleoplasm Cytosol "HPA007296: , HPA024331: " "unprognostic (3.03e-2)" "unprognostic (1.77e-1)" "unprognostic (1.74e-1)" "unprognostic (1.75e-2)" "unprognostic (3.20e-2)" "unprognostic (1.73e-2)" "unprognostic (2.36e-2)" "potential prognostic favorable (5.30e-5)" "unprognostic (1.03e-1)" "potential prognostic unfavorable (4.47e-4)" "validated prognostic favorable (3.20e-5)" "validated prognostic favorable (1.81e-4)" "unprognostic (3.19e-3)" "unprognostic (3.32e-3)" "potential prognostic unfavorable (8.14e-4)" "unprognostic (6.07e-2)" "unprognostic (8.51e-2)" "unprognostic (5.88e-2)" "unprognostic (3.54e-1)" "unprognostic (2.58e-1)" "unprognostic (3.65e-2)" "unprognostic (3.67e-3)" "unprognostic (4.98e-2)" "unprognostic (3.11e-1)" "unprognostic (7.29e-2)" "unprognostic (1.96e-2)" "unprognostic (1.40e-3)" "unprognostic (2.33e-2)" "unprognostic (1.49e-2)" "unprognostic (2.62e-1)" "unprognostic (1.28e-2)" ZSCAN20 "KOX29, ZNF31, ZNF360" ENSG00000121903 "Zinc finger and SCAN domain containing 20" P17040 1 33472645-33501643 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 13.9;Early spermatids: 25.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017933 Uncertain Approved Nucleoplasm NA NA "Cluster 69: Parathyroid gland - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 37: Non-specific - mRNA processing" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 4 Nucleoplasm "HPA017933: " "unprognostic (6.89e-2)" "unprognostic (1.10e-1)" "unprognostic (3.35e-1)" "unprognostic (2.15e-2)" "unprognostic (1.18e-1)" "unprognostic (8.12e-2)" "unprognostic (2.09e-1)" "unprognostic (2.31e-2)" "unprognostic (5.16e-3)" "unprognostic (1.18e-3)" "potential prognostic favorable (7.03e-4)" "unprognostic (1.87e-1)" "unprognostic (2.06e-1)" "unprognostic (2.21e-2)" "unprognostic (1.56e-1)" "unprognostic (2.87e-1)" "unprognostic (3.22e-2)" "unprognostic (1.32e-1)" "unprognostic (4.27e-1)" "unprognostic (1.42e-1)" "unprognostic (4.93e-2)" "unprognostic (1.12e-1)" "unprognostic (1.73e-1)" "unprognostic (5.43e-1)" "unprognostic (2.32e-2)" "unprognostic (5.25e-2)" ZSCAN21 "DKFZp434L134, NY-REN-21, Zipro1, ZNF38" ENSG00000166529 "Zinc finger and SCAN domain containing 21" Q9Y5A6 7 100049774-100065040 "Predicted intracellular proteins, Transcription factors" "Differentiation, Meiosis, Spermatogenesis, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016948, HPA023591" Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 32: Basophils - Transcription" "Cluster 21: Testis - Mixed function" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 11: Muller glia cells - Retinal homeostasis" 41 "Endoplasmic reticulum" "HPA016948: , HPA023591: " "unprognostic (3.90e-3)" "unprognostic (8.99e-2)" "unprognostic (1.47e-1)" "potential prognostic unfavorable (1.80e-5)" "unprognostic (9.75e-2)" "unprognostic (1.41e-2)" "unprognostic (4.67e-2)" "unprognostic (1.86e-1)" "unprognostic (3.73e-1)" "unprognostic (1.05e-2)" "unprognostic (2.08e-3)" "unprognostic (4.03e-2)" "unprognostic (1.36e-2)" "unprognostic (1.49e-1)" "unprognostic (1.43e-1)" "unprognostic (1.85e-1)" "unprognostic (1.85e-1)" "potential prognostic favorable (2.07e-4)" "unprognostic (2.81e-3)" "unprognostic (2.43e-1)" "unprognostic (2.22e-1)" "potential prognostic favorable (5.84e-5)" "unprognostic (2.39e-1)" "unprognostic (1.33e-2)" "unprognostic (1.10e-1)" "unprognostic (1.24e-1)" "unprognostic (4.71e-3)" "unprognostic (1.33e-1)" "unprognostic (1.44e-1)" "potential prognostic unfavorable (7.71e-4)" "unprognostic (1.25e-2)" ZSCAN22 "HKR2, ZNF50" ENSG00000182318 "Zinc finger and SCAN domain containing 22" P10073 19 58326994-58342332 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 6.7;Epicardial cells: 6.8;Retinal ganglion cells: 7.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006471 Uncertain Uncertain "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 64: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 31 "Plasma membrane, Cytosol" "Actin filaments" "HPA006471: " "unprognostic (9.40e-3)" "unprognostic (6.27e-3)" "unprognostic (1.39e-1)" "unprognostic (3.61e-2)" "unprognostic (1.60e-1)" "unprognostic (4.21e-2)" "unprognostic (2.74e-1)" "unprognostic (1.36e-2)" "unprognostic (9.15e-2)" "unprognostic (3.55e-2)" "unprognostic (6.31e-3)" "unprognostic (9.03e-3)" "unprognostic (3.06e-1)" "potential prognostic unfavorable (1.86e-4)" "unprognostic (2.16e-1)" "unprognostic (3.09e-1)" "unprognostic (9.04e-2)" "unprognostic (7.65e-3)" "unprognostic (3.84e-2)" "unprognostic (6.19e-2)" "unprognostic (1.19e-1)" "unprognostic (6.58e-2)" "unprognostic (2.99e-1)" "unprognostic (8.82e-2)" "unprognostic (3.69e-2)" "unprognostic (3.37e-1)" "unprognostic (2.09e-1)" "unprognostic (3.01e-2)" "unprognostic (2.09e-1)" "unprognostic (1.96e-2)" "unprognostic (1.93e-1)" ZSCAN23 "dJ29K1.3.1, ZNF390, ZNF453" ENSG00000187987 "Zinc finger and SCAN domain containing 23" Q3MJ62 6 28431930-28443502 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Bergmann glia: 25.2;Choroid plexus epithelial cells: 31.7;Oligodendrocyte progenitor cells: 24.5;Pituitary stem cells: 23.2" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA035959, HPA035960" Uncertain Approved "Nuclear speckles,Golgi apparatus" NA NA "Cluster 61: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 29 "Nuclear speckles" "Golgi apparatus" "HPA035959: , HPA035960: " "unprognostic (1.34e-1)" "unprognostic (2.16e-2)" "unprognostic (1.09e-1)" ZSCAN25 "FLJ32468, ZNF498" ENSG00000197037 "Zinc finger and SCAN domain containing 25" Q6NSZ9 7 99616946-99632408 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055127, HPA057173" Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 15: Non-specific - Transcription" "Cluster 39: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 1 "Nucleoli fibrillar center" Nucleoplasm "HPA055127: , HPA057173: " "unprognostic (1.06e-2)" "unprognostic (3.63e-2)" "unprognostic (7.57e-2)" "unprognostic (3.20e-1)" "unprognostic (1.20e-1)" "unprognostic (1.34e-1)" "unprognostic (3.45e-2)" "unprognostic (7.38e-2)" "unprognostic (3.74e-2)" "potential prognostic favorable (6.00e-6)" "unprognostic (8.80e-3)" "unprognostic (7.67e-2)" "potential prognostic unfavorable (6.87e-4)" "unprognostic (3.16e-1)" "unprognostic (6.50e-2)" "unprognostic (2.82e-2)" "unprognostic (1.15e-3)" "unprognostic (1.40e-1)" "unprognostic (1.34e-1)" "unprognostic (3.18e-3)" "unprognostic (2.80e-3)" "unprognostic (6.01e-2)" "unprognostic (6.81e-3)" "unprognostic (1.19e-2)" "unprognostic (6.38e-2)" "unprognostic (5.44e-2)" "unprognostic (2.40e-1)" "unprognostic (3.72e-2)" "unprognostic (8.67e-3)" ZSCAN26 "SRE-ZBP, ZNF187" ENSG00000197062 "Zinc finger and SCAN domain containing 26" Q16670 6 28267058-28278224 "Essential proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.4;Gastric chief cells: 1.1;Medullary thymic epithelial cells: 2.4;Sertoli cells: 1.1;Thymic myoid cells: 1.4" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027521 Enhanced Nucleoplasm,Nucleoli NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 65: Brain - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 16 "Nucleoplasm, Nucleoli" "HPA027521: " "unprognostic (4.95e-3)" "unprognostic (2.27e-1)" "unprognostic (1.26e-1)" "unprognostic (2.71e-1)" "unprognostic (1.11e-1)" "unprognostic (1.39e-3)" "potential prognostic favorable (2.13e-4)" "unprognostic (3.77e-3)" "unprognostic (1.52e-1)" "unprognostic (2.32e-2)" "unprognostic (1.36e-3)" "unprognostic (3.37e-2)" "potential prognostic unfavorable (5.35e-5)" "unprognostic (1.16e-3)" "unprognostic (2.28e-1)" "unprognostic (3.39e-1)" "unprognostic (1.67e-1)" "unprognostic (1.12e-1)" "unprognostic (3.98e-2)" "unprognostic (5.26e-3)" "unprognostic (2.99e-3)" "unprognostic (3.59e-2)" "unprognostic (1.72e-2)" "unprognostic (2.04e-1)" "unprognostic (1.50e-2)" "unprognostic (5.29e-2)" "unprognostic (2.15e-1)" "unprognostic (6.77e-2)" "unprognostic (1.41e-1)" ZSCAN29 "FLJ35867, Zfp690, ZNF690" ENSG00000140265 "Zinc finger and SCAN domain containing 29" Q8IWY8 15 43358172-43371043 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Early spermatids: 131.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 3.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007241, HPA011109" Enhanced Approved "Nucleoplasm,Plasma membrane,Actin filaments" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 1 Nucleoplasm "Plasma membrane, Actin filaments" "HPA007241: , HPA011109: " "unprognostic (1.31e-2)" "unprognostic (1.77e-2)" "unprognostic (2.18e-1)" "potential prognostic unfavorable (1.91e-4)" "unprognostic (1.28e-1)" "unprognostic (2.74e-2)" "unprognostic (8.47e-2)" "potential prognostic favorable (5.32e-4)" "unprognostic (6.77e-2)" "unprognostic (2.12e-3)" "potential prognostic favorable (3.08e-4)" "unprognostic (3.87e-3)" "unprognostic (2.93e-1)" "unprognostic (1.34e-2)" "unprognostic (6.49e-2)" "unprognostic (3.39e-1)" "unprognostic (1.16e-1)" "unprognostic (1.01e-1)" "unprognostic (1.86e-2)" "unprognostic (6.46e-3)" "unprognostic (3.23e-1)" "unprognostic (3.21e-1)" "unprognostic (2.90e-2)" "unprognostic (7.90e-2)" "unprognostic (4.26e-2)" "unprognostic (1.61e-1)" "unprognostic (1.17e-1)" "unprognostic (4.74e-2)" "unprognostic (2.25e-1)" "unprognostic (7.02e-2)" "unprognostic (2.95e-1)" ZSCAN30 "ZNF397OS, ZNF917" ENSG00000186814 "Zinc finger and SCAN domain containing 30" Q86W11 18 35251058-35290245 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 79.5;Myonuclei: 129.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" HPA007289 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 34: B-cells - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 9: Non-specific - Receptor signaling" "Cluster 13: Non-specific - Mixed function" "Cluster 55: Myocytes - Oxidative muscle function" 4 Nucleoplasm Cytosol "HPA007289: " "unprognostic (2.41e-2)" "unprognostic (6.26e-2)" "unprognostic (1.08e-2)" "unprognostic (1.36e-1)" "unprognostic (1.00e-1)" "unprognostic (2.63e-1)" "unprognostic (9.00e-3)" "unprognostic (4.51e-3)" "unprognostic (1.40e-2)" "unprognostic (3.27e-1)" "unprognostic (2.38e-3)" "unprognostic (5.29e-3)" "unprognostic (2.36e-2)" "unprognostic (7.95e-2)" "unprognostic (7.53e-3)" "unprognostic (2.86e-2)" "unprognostic (3.10e-2)" "unprognostic (7.08e-2)" "unprognostic (1.85e-1)" "unprognostic (4.12e-2)" "unprognostic (3.04e-2)" "unprognostic (7.72e-3)" "unprognostic (1.19e-2)" "unprognostic (6.10e-2)" "unprognostic (1.24e-1)" "unprognostic (1.00e-1)" "unprognostic (2.07e-1)" "unprognostic (1.77e-3)" "unprognostic (3.84e-2)" "unprognostic (3.67e-2)" ZSCAN31 "ZNF310P, ZNF323" ENSG00000235109 "Zinc finger and SCAN domain containing 31" Q96LW9 6 28324693-28356271 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 71.9;Early spermatids: 146.7;Lactotrophs: 65.8;Late primary spermatocytes: 97.2;Late spermatids: 77.7;Myonuclei: 98.2;Pancreatic acinar cells: 75.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 10 "basophil: 17.6" "Lineage enriched" "Detected in many" 10 "granulocytes: 17.6" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" HPA007124 Approved Approved Nucleoplasm,Cytosol NA Yes "Cluster 24: Non-specific - Transcription" "Cluster 21: Testis - Mixed function" "Cluster 34: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 55: Myocytes - Oxidative muscle function" 3 Nucleoplasm Cytosol "HPA007124: " "unprognostic (1.54e-1)" "unprognostic (1.95e-1)" "unprognostic (1.54e-1)" "unprognostic (2.45e-1)" "unprognostic (3.88e-1)" "unprognostic (3.18e-3)" "unprognostic (3.49e-1)" "unprognostic (7.97e-2)" "unprognostic (7.00e-3)" "validated prognostic favorable (1.10e-5)" "validated prognostic favorable (6.95e-6)" "unprognostic (4.22e-2)" "unprognostic (3.79e-2)" "unprognostic (8.44e-2)" "unprognostic (2.22e-1)" "unprognostic (1.54e-1)" "unprognostic (7.46e-2)" "unprognostic (5.89e-2)" "unprognostic (1.75e-1)" "unprognostic (9.80e-2)" "unprognostic (1.52e-1)" "unprognostic (2.98e-1)" "unprognostic (1.20e-3)" "unprognostic (1.80e-1)" "unprognostic (1.27e-1)" "unprognostic (5.53e-3)" "unprognostic (2.11e-1)" "unprognostic (2.76e-1)" "unprognostic (2.84e-2)" ZSCAN32 "FLJ20417, ZNF434" ENSG00000140987 "Zinc finger and SCAN domain containing 32" Q9NX65 16 3382081-3401065 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 83.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA005758 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 65: Brain - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 54: Non-specific - Transcription" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 28 Nucleoplasm Cytosol "HPA005758: " "unprognostic (1.14e-1)" "unprognostic (3.78e-2)" "unprognostic (9.01e-3)" "unprognostic (5.41e-2)" "unprognostic (3.86e-2)" "unprognostic (3.12e-2)" "unprognostic (4.61e-1)" "unprognostic (9.71e-2)" "unprognostic (4.03e-2)" "unprognostic (1.27e-3)" "unprognostic (7.75e-2)" "unprognostic (7.19e-2)" "unprognostic (1.31e-1)" "unprognostic (4.49e-2)" "unprognostic (2.84e-1)" "unprognostic (8.27e-2)" "unprognostic (1.49e-2)" "unprognostic (2.22e-2)" "unprognostic (1.01e-1)" "unprognostic (6.28e-3)" "unprognostic (7.44e-2)" "unprognostic (1.42e-2)" "unprognostic (2.60e-2)" "unprognostic (2.34e-1)" "unprognostic (1.54e-2)" "unprognostic (1.20e-1)" "unprognostic (1.05e-1)" "unprognostic (3.01e-2)" "unprognostic (4.10e-2)" ZSCAN4 "FLJ35105, ZNF494" ENSG00000180532 "Zinc finger and SCAN domain containing 4" Q8NAM6 19 57668935-57679152 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "stomach 1: 2.4" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 1.5;Epididymal basal cells: 1.1;Fallopian tube ciliated cells: 1.6;Foveolar cells: 1.3;Lymphatic endothelial cells: 2.8;Medullary thymic epithelial cells: 2.4;Papillary tip epithelial cells: 1.8;Prostatic hillock cells: 1.2;Salivary basal cells: 1.2;Salivary duct cells: 1.4;Salivary ionocytes: 1.1;Syncytiotrophoblasts: 2.6;Urothelial cells: 1.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Bladder Urothelial Carcinoma (TCGA): 1.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Smooth muscle cells, Prostate - Urothelial cells, Stomach - Gastric mucous cells" HPA006491 Uncertain NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 48: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 10 "HPA006491: " "unprognostic (5.33e-2)" ZSCAN5A "MGC4161, ZNF495, ZSCAN5" ENSG00000131848 "Zinc finger and SCAN domain containing 5A" Q9BUG6 19 56219670-56368383 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 17.0" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 247.4;Early spermatids: 270.8;Ependymal cells: 177.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "HPA041263, HPA043123, HPA046836, HPA060667" Uncertain Uncertain "Nuclear speckles" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 4: Non-specific - Transcription" "Cluster 34: Ciliated cells - Cilia assembly & function" 21 "Nuclear speckles" "HPA041263: , HPA043123: , HPA046836: , HPA060667: " "unprognostic (3.79e-2)" "unprognostic (3.37e-1)" "unprognostic (7.30e-2)" "unprognostic (4.56e-1)" "unprognostic (2.89e-3)" "unprognostic (4.36e-3)" "unprognostic (8.57e-3)" "unprognostic (5.74e-2)" "unprognostic (1.39e-1)" "unprognostic (1.09e-1)" "potential prognostic favorable (1.09e-6)" "unprognostic (4.22e-2)" "unprognostic (4.90e-3)" "unprognostic (1.98e-3)" "unprognostic (4.08e-2)" "unprognostic (3.47e-1)" "unprognostic (1.11e-1)" "unprognostic (6.23e-2)" "unprognostic (3.61e-2)" "unprognostic (2.41e-1)" "unprognostic (1.04e-1)" "unprognostic (3.54e-2)" "unprognostic (4.86e-1)" "unprognostic (1.18e-1)" "unprognostic (2.86e-3)" "unprognostic (5.31e-2)" "unprognostic (3.64e-1)" "unprognostic (2.03e-1)" "unprognostic (7.21e-2)" "unprognostic (2.81e-2)" "unprognostic (2.46e-1)" ZSCAN5B "ZNF371, ZNF495B" ENSG00000197213 "Zinc finger and SCAN domain containing 5B" A6NJL1 19 56189686-56197815 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "testis: 1.7" "Group enriched" "Detected in some" 7 "Differentiating spermatogonia: 7.8;Undifferentiated spermatogonia: 8.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 16 "liver cancer: 1.6" "Testis - Spermatogonia" "HPA043123, HPA046836, HPA059494, HPA060667" Uncertain Uncertain "Nuclear speckles" NA NA "Cluster 67: Testis - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 1 "Nuclear speckles" "HPA043123: , HPA046836: , HPA059494: , HPA060667: " ZSCAN5C "ZNF495C, ZSCAN5CP" ENSG00000204532 "Zinc finger and SCAN domain containing 5C" A6NGD5 19 56202273-56209461 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041263, HPA043123, HPA046836, HPA060667" Uncertain Uncertain "Nuclear speckles" NA NA "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 65: Non-specific - Cell growth & division" "Nuclear speckles" "HPA041263: , HPA043123: , HPA046836: , HPA060667: " ZSCAN9 "PRD51, ZNF193" ENSG00000137185 "Zinc finger and SCAN domain containing 9" O15535 6 28224886-28233487 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "HPA054512, HPA059951" Uncertain Approved Nucleoplasm,Cytosol No No "Cluster 14: Non-specific - Unknown function" "Cluster 67: Testis - Mixed function" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 28: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" 26 Nucleoplasm Cytosol "HPA054512: , HPA059951: " "potential prognostic favorable (1.70e-6)" "unprognostic (5.76e-3)" "unprognostic (4.96e-2)" "unprognostic (2.21e-1)" "unprognostic (1.28e-1)" "unprognostic (1.52e-2)" "unprognostic (9.31e-3)" "unprognostic (2.76e-2)" "unprognostic (4.92e-2)" "unprognostic (5.64e-2)" "unprognostic (7.68e-3)" "unprognostic (5.51e-2)" "potential prognostic unfavorable (2.47e-5)" "unprognostic (6.52e-2)" "unprognostic (4.04e-2)" "unprognostic (1.23e-1)" "unprognostic (2.23e-2)" "unprognostic (2.70e-1)" "unprognostic (2.60e-1)" "unprognostic (6.08e-2)" "unprognostic (2.77e-2)" "unprognostic (1.33e-2)" "unprognostic (1.89e-3)" "unprognostic (2.45e-2)" "unprognostic (2.68e-2)" "unprognostic (1.69e-2)" "unprognostic (2.30e-1)" "unprognostic (8.21e-2)" "unprognostic (1.77e-1)" ZSWIM1 "C20orf162, dJ337O18.5" ENSG00000168612 "Zinc finger SWIM-type containing 1" Q9BR11 20 45881227-45885266 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 10.6;Cardiomyocytes: 17.3;Epicardial cells: 9.1;Megakaryocytes: 12.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041147, HPA046751" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 24: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "Plasma membrane, Cytosol" "HPA041147: , HPA046751: " "unprognostic (6.71e-2)" "potential prognostic unfavorable (5.79e-4)" "unprognostic (2.88e-1)" "unprognostic (2.44e-3)" "unprognostic (1.10e-1)" "unprognostic (2.76e-1)" "unprognostic (1.09e-1)" "potential prognostic favorable (3.10e-4)" "unprognostic (2.50e-2)" "unprognostic (2.18e-2)" "unprognostic (2.29e-1)" "unprognostic (4.57e-2)" "potential prognostic favorable (6.95e-4)" "potential prognostic unfavorable (1.29e-4)" "unprognostic (2.36e-2)" "unprognostic (3.57e-1)" "unprognostic (1.89e-3)" "unprognostic (2.14e-2)" "unprognostic (1.23e-2)" "unprognostic (8.48e-2)" "unprognostic (1.16e-2)" "unprognostic (4.30e-2)" "unprognostic (7.61e-2)" "unprognostic (4.37e-2)" "unprognostic (2.13e-3)" "unprognostic (6.27e-2)" "unprognostic (3.03e-2)" "unprognostic (2.79e-1)" "unprognostic (7.04e-2)" "unprognostic (8.75e-3)" "unprognostic (1.73e-1)" ZSWIM2 "MEX, MGC33890, ZZZ2" ENSG00000163012 "Zinc finger SWIM-type containing 2" Q8NEG5 2 186827475-186849208 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 13 "testis: 8.7" "Group enriched" "Detected in some" 5 "Early spermatids: 61.8;Late primary spermatocytes: 76.2;Late spermatids: 24.3" "Cell type enhanced" "Detected in many" "ependymal cell: 9.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal medulla cells, Breast - Adipocytes (Breast), Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 5: Rhabdoid - Unknown function" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 1 ZSWIM3 "C20orf164, dJ337O18.7, PPP1R174" ENSG00000132801 "Zinc finger SWIM-type containing 3" Q96MP5 20 45857614-45879122 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 26.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055692, HPA060508" Uncertain Approved "Nucleoli fibrillar center,Vesicles,Cytosol" NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 62: Non-specific - Plasma proteins" "Cluster 65: Non-specific - Cell growth & division" 2 Vesicles "Nucleoli fibrillar center, Cytosol" "HPA055692: , HPA060508: " "unprognostic (8.82e-2)" "potential prognostic unfavorable (5.29e-5)" "unprognostic (1.97e-1)" "unprognostic (2.26e-1)" "unprognostic (2.00e-1)" "unprognostic (2.10e-1)" "unprognostic (1.44e-1)" "potential prognostic favorable (2.05e-4)" "unprognostic (5.26e-3)" "unprognostic (3.69e-1)" "unprognostic (1.59e-2)" "unprognostic (1.85e-1)" "unprognostic (2.87e-3)" "potential prognostic unfavorable (4.54e-5)" "unprognostic (1.13e-3)" "unprognostic (4.27e-2)" "unprognostic (6.45e-2)" "unprognostic (1.73e-1)" "unprognostic (3.81e-1)" "unprognostic (6.30e-2)" "unprognostic (4.73e-2)" "unprognostic (5.05e-3)" "unprognostic (1.54e-1)" "unprognostic (4.43e-2)" "unprognostic (8.11e-3)" "unprognostic (3.78e-1)" "unprognostic (5.08e-2)" "unprognostic (2.86e-2)" "unprognostic (2.35e-1)" "unprognostic (1.23e-1)" "unprognostic (1.69e-2)" ZSWIM4 FLJ12221 ENSG00000132003 "Zinc finger SWIM-type containing 4" Q9H7M6 19 13795443-13832254 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 11.0" "Cell type enhanced" "Detected in some" "Astrocytes: 7.5;Choroid plexus epithelial cells: 9.4;Distal convoluted tubule cells: 13.9;Ependymal cells: 11.0;Loop of henle epithelial cells: 20.2;Microglia: 9.3;Oligodendrocyte progenitor cells: 11.5;Papillary tip epithelial cells: 32.3;Podocytes: 13.4;Proximal tubule cells: 17.8;Renal collecting duct intercalated cells: 12.2;Renal collecting duct principal cells: 21.4;Renal connecting tubule cells: 20.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042084 Uncertain NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 18: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 105: Non-specific - Mixed function" "HPA042084: " "unprognostic (9.23e-3)" "unprognostic (2.64e-2)" "unprognostic (1.30e-1)" "unprognostic (2.49e-3)" "unprognostic (2.99e-1)" "unprognostic (1.11e-2)" "unprognostic (1.27e-1)" "unprognostic (3.65e-1)" "potential prognostic favorable (3.28e-4)" "unprognostic (1.21e-1)" "unprognostic (1.99e-1)" "unprognostic (6.62e-2)" "unprognostic (4.02e-2)" "potential prognostic unfavorable (4.60e-4)" "potential prognostic favorable (5.59e-4)" "unprognostic (9.34e-2)" "unprognostic (8.51e-2)" "unprognostic (4.20e-2)" "unprognostic (4.64e-2)" "unprognostic (3.82e-3)" "unprognostic (3.86e-2)" "unprognostic (3.10e-1)" "unprognostic (7.30e-3)" "unprognostic (7.61e-2)" "unprognostic (8.44e-2)" "potential prognostic favorable (1.17e-4)" "unprognostic (2.31e-1)" "unprognostic (2.18e-1)" "unprognostic (1.84e-1)" "unprognostic (3.72e-1)" "unprognostic (2.86e-1)" ZSWIM5 KIAA1511 ENSG00000162415 "Zinc finger SWIM-type containing 5" Q9P217 1 45016399-45306209 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 529.2;Bergmann glia: 322.7;Cone photoreceptor cells: 306.4;Lactotrophs: 331.9;Podocytes: 254.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Pituitary gland - Lactotropes, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018211 Uncertain Approved "Nuclear speckles" NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 18: Adrenal cortex cells - Steroidogensis" 1 "Nuclear speckles" "HPA018211: " "unprognostic (1.61e-1)" "unprognostic (2.49e-1)" "unprognostic (9.08e-2)" "unprognostic (4.77e-2)" "unprognostic (1.42e-1)" "unprognostic (3.46e-2)" "unprognostic (1.43e-1)" "unprognostic (1.06e-3)" "unprognostic (6.06e-2)" "potential prognostic favorable (6.06e-8)" "unprognostic (2.78e-3)" "potential prognostic favorable (5.72e-4)" "unprognostic (2.17e-3)" "potential prognostic unfavorable (2.74e-4)" "unprognostic (7.98e-2)" "unprognostic (1.70e-1)" "unprognostic (2.39e-1)" "unprognostic (1.94e-1)" "unprognostic (2.65e-1)" "unprognostic (4.99e-3)" "unprognostic (9.11e-3)" "unprognostic (1.12e-1)" "unprognostic (2.38e-2)" "unprognostic (3.27e-1)" "unprognostic (6.01e-2)" "unprognostic (7.18e-2)" "unprognostic (9.69e-3)" "unprognostic (2.71e-2)" "unprognostic (1.08e-1)" ZSWIM6 KIAA1577 ENSG00000130449 "Zinc finger SWIM-type containing 6" Q9HCJ5 5 61332258-61546172 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Neurogenesis "Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 3330.7;Podocytes: 1946.6;Respiratory basal cells: 2091.7;Salivary basal cells: 1985.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035938 Uncertain Approved Cytosol NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 1 Cytosol "HPA035938: " "unprognostic (4.86e-3)" "unprognostic (2.78e-1)" "unprognostic (2.14e-2)" "unprognostic (6.54e-2)" "unprognostic (1.30e-1)" "unprognostic (1.74e-1)" "unprognostic (1.69e-1)" "unprognostic (4.95e-2)" "unprognostic (3.34e-2)" "unprognostic (9.68e-2)" "unprognostic (8.27e-3)" "unprognostic (1.21e-2)" "unprognostic (3.92e-1)" "unprognostic (1.37e-1)" "unprognostic (2.82e-2)" "unprognostic (3.41e-2)" "unprognostic (2.44e-3)" "unprognostic (1.54e-1)" "unprognostic (5.57e-2)" "unprognostic (2.57e-2)" "unprognostic (6.74e-2)" "unprognostic (4.61e-2)" "unprognostic (9.19e-3)" "unprognostic (9.56e-2)" "unprognostic (1.61e-2)" "unprognostic (1.89e-1)" "unprognostic (3.71e-1)" "unprognostic (9.64e-3)" "unprognostic (6.36e-2)" "unprognostic (1.87e-1)" "unprognostic (9.40e-2)" ZSWIM7 SWS1 ENSG00000214941 "Zinc finger SWIM-type containing 7" Q19AV6 17 15976560-15999717 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054681 Uncertain Uncertain Cytosol NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 53: Neurons - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 7 Cytosol "HPA054681: " "unprognostic (2.78e-2)" "unprognostic (2.80e-2)" "unprognostic (2.00e-1)" "unprognostic (2.03e-2)" "unprognostic (2.31e-1)" "unprognostic (2.00e-2)" "unprognostic (1.25e-1)" "unprognostic (1.99e-3)" "unprognostic (1.27e-1)" "unprognostic (9.34e-2)" "potential prognostic favorable (3.67e-5)" "unprognostic (3.23e-2)" "unprognostic (1.27e-1)" "unprognostic (1.99e-2)" "unprognostic (3.01e-3)" "unprognostic (6.74e-2)" "unprognostic (6.87e-2)" "unprognostic (7.36e-3)" "unprognostic (9.30e-3)" "unprognostic (1.89e-2)" "unprognostic (8.64e-2)" "potential prognostic favorable (3.34e-4)" "unprognostic (2.53e-1)" "unprognostic (3.54e-2)" "unprognostic (1.43e-2)" "unprognostic (2.30e-1)" "unprognostic (3.18e-2)" "unprognostic (1.87e-1)" "unprognostic (1.57e-1)" "unprognostic (1.42e-2)" "unprognostic (8.92e-2)" ZSWIM8 "4832404P21Rik, KIAA0913" ENSG00000214655 "Zinc finger SWIM-type containing 8" A7E2V4 10 73785606-73801797 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 128.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041244 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 70: Non-specific - Protein processing" "Cluster 34: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 7: Non-specific - Transcription" 4 "Plasma membrane, Cytosol" "HPA041244: " "unprognostic (7.88e-2)" "unprognostic (2.21e-1)" "unprognostic (9.73e-2)" "unprognostic (7.01e-2)" "unprognostic (5.66e-2)" "unprognostic (3.32e-1)" "potential prognostic favorable (1.87e-5)" "unprognostic (6.54e-2)" "unprognostic (1.09e-2)" "potential prognostic unfavorable (1.30e-4)" "unprognostic (2.97e-2)" "unprognostic (1.57e-2)" "unprognostic (1.06e-1)" "unprognostic (7.95e-2)" "unprognostic (8.22e-2)" "unprognostic (2.24e-1)" "unprognostic (4.35e-1)" "unprognostic (1.92e-1)" "unprognostic (2.25e-2)" "unprognostic (1.38e-3)" "unprognostic (4.12e-3)" "unprognostic (1.80e-1)" "unprognostic (1.08e-2)" "unprognostic (1.17e-1)" "unprognostic (1.52e-1)" "unprognostic (9.39e-2)" "unprognostic (4.59e-2)" "unprognostic (3.49e-1)" "unprognostic (4.96e-2)" ZSWIM9 "C19orf68, LOC374920" ENSG00000185453 "Zinc finger SWIM-type containing 9" Q86XI8 19 48170680-48197620 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.6" "Cell type enhanced" "Detected in many" "Early spermatids: 45.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061028 Uncertain Approved Nucleoplasm NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 4 Nucleoplasm "HPA061028: " "unprognostic (1.10e-3)" "unprognostic (2.61e-1)" "unprognostic (1.64e-2)" "unprognostic (4.07e-1)" "unprognostic (5.12e-2)" "unprognostic (1.41e-2)" "unprognostic (1.15e-1)" "unprognostic (8.40e-2)" "unprognostic (6.52e-2)" "validated prognostic favorable (2.68e-5)" "validated prognostic favorable (4.05e-4)" "unprognostic (7.66e-2)" "potential prognostic unfavorable (1.29e-6)" "unprognostic (1.49e-3)" "unprognostic (1.91e-1)" "unprognostic (1.78e-1)" "unprognostic (2.27e-1)" "unprognostic (1.40e-2)" "unprognostic (6.66e-2)" "unprognostic (1.30e-3)" "unprognostic (1.93e-1)" "unprognostic (6.58e-2)" "unprognostic (3.04e-1)" "potential prognostic favorable (4.53e-4)" "unprognostic (9.26e-2)" "unprognostic (2.28e-1)" "unprognostic (1.16e-1)" "unprognostic (1.09e-1)" "unprognostic (2.47e-1)" ZUP1 "C6orf113, dJ412I7.3, ZUFSP" ENSG00000153975 "Zinc finger containing ubiquitin peptidase 1" Q96AP4 6 116635618-116668794 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044426, HPA076940" Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 9 Nucleoplasm Cytosol "HPA044426: , HPA076940: " "unprognostic (1.24e-1)" "potential prognostic unfavorable (1.77e-4)" "unprognostic (9.33e-2)" "unprognostic (3.78e-2)" "unprognostic (1.01e-2)" "unprognostic (1.35e-2)" "potential prognostic favorable (8.98e-4)" "unprognostic (2.34e-1)" "unprognostic (5.70e-2)" "potential prognostic favorable (2.66e-5)" "unprognostic (6.38e-2)" "unprognostic (1.11e-1)" "potential prognostic unfavorable (1.81e-4)" "unprognostic (9.44e-3)" "unprognostic (3.27e-2)" "unprognostic (2.50e-1)" "unprognostic (2.57e-1)" "unprognostic (4.05e-2)" "unprognostic (9.38e-2)" "unprognostic (1.90e-1)" "potential prognostic unfavorable (1.08e-5)" "unprognostic (5.24e-2)" "unprognostic (3.31e-3)" "unprognostic (2.52e-3)" "unprognostic (1.22e-1)" "unprognostic (8.76e-2)" "unprognostic (1.85e-1)" "unprognostic (6.44e-2)" "unprognostic (1.48e-1)" ZW10 KNTC1AP ENSG00000086827 "Zw10 kinetochore protein" O43264 11 113733187-113773735 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, ER-Golgi transport, Mitosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 63.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011565, HPA051253, HPA055410" Enhanced Supported "Endoplasmic reticulum,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 39: Testis - Nuclear processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 50 "Endoplasmic reticulum, Cytosol" "CAB011565: , HPA051253: , HPA055410: " "unprognostic (1.03e-2)" "unprognostic (9.95e-3)" "unprognostic (4.31e-1)" "unprognostic (3.32e-2)" "unprognostic (4.17e-2)" "unprognostic (1.45e-1)" "unprognostic (4.58e-2)" "unprognostic (1.08e-1)" "unprognostic (3.28e-2)" "unprognostic (1.81e-1)" "potential prognostic favorable (8.28e-7)" "unprognostic (4.27e-2)" "unprognostic (2.74e-1)" "potential prognostic unfavorable (8.35e-5)" "unprognostic (8.02e-2)" "unprognostic (2.48e-2)" "unprognostic (1.83e-3)" "unprognostic (6.61e-2)" "unprognostic (1.00e-1)" "unprognostic (1.46e-1)" "unprognostic (4.36e-3)" "unprognostic (1.80e-3)" "unprognostic (1.47e-1)" "unprognostic (2.40e-2)" "unprognostic (4.47e-3)" "unprognostic (2.17e-1)" "unprognostic (6.95e-2)" "unprognostic (2.43e-1)" "unprognostic (1.90e-1)" "unprognostic (6.97e-2)" "unprognostic (1.40e-1)" ZWILCH "FLJ10036, KNTC1AP" ENSG00000174442 "Zwilch kinetochore protein" Q9H900 15 66504959-66550130 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 50.4" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 64.0;Early primary spermatocytes: 114.3;Early spermatids: 116.0;Late primary spermatocytes: 206.2;Late spermatids: 117.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 39: Testis - Nuclear processes" "Cluster 21: Non-specific - Metabolism" "Cluster 58: Non-specific - Nuclear processes" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 2 "unprognostic (6.01e-2)" "unprognostic (1.34e-1)" "unprognostic (3.70e-1)" "unprognostic (2.16e-2)" "unprognostic (1.22e-1)" "unprognostic (2.37e-1)" "unprognostic (2.35e-1)" "unprognostic (5.23e-2)" "unprognostic (1.16e-2)" "unprognostic (7.22e-3)" "unprognostic (9.63e-2)" "unprognostic (2.46e-1)" "unprognostic (6.23e-3)" "unprognostic (3.54e-2)" "potential prognostic unfavorable (1.40e-4)" "unprognostic (1.33e-3)" "unprognostic (3.29e-3)" "unprognostic (8.46e-3)" "unprognostic (2.15e-1)" "unprognostic (2.55e-1)" "unprognostic (4.26e-2)" "potential prognostic unfavorable (2.97e-4)" "unprognostic (3.20e-2)" "unprognostic (3.17e-2)" "unprognostic (2.96e-3)" "unprognostic (1.51e-1)" "unprognostic (8.51e-3)" "unprognostic (5.88e-2)" "unprognostic (2.53e-1)" "unprognostic (1.42e-1)" "unprognostic (3.87e-2)" ZWINT "KNTC2AP, SIP30, Zwint1" ENSG00000122952 "ZW10 interacting kinetochore protein" O95229 10 56357227-56361273 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 39.2;lymphoid tissue: 40.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 80.0;Differentiating spermatogonia: 103.4;Early primary spermatocytes: 128.6;Early spermatids: 67.1;Enteric transient amplifying cells: 80.7;Erythrocyte progenitors: 93.6;Esophageal basal cells: 91.9;Extravillous trophoblasts: 122.6;Gastric progenitor cells: 103.8;Hofbauer cells: 72.3;Late primary spermatocytes: 141.9;Late spermatids: 301.0;Megakaryocyte progenitors: 80.3;Migrating cytotrophoblasts: 106.8;Oocytes: 138.2" "Cell type enhanced" "Detected in many" "hippocampal CA4: 5.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "T-reg: 17.0" "Lineage enriched" "Detected in many" 5 "T-cells: 17.0" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "HPA005757, HPA022264" Enhanced "Nucleoplasm,Nuclear bodies,Cytosol" No Yes "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 38: Sub-cortical - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 27: Non-specific - Cell proliferation" 58 "Nucleoplasm, Nuclear bodies" Cytosol "HPA005757: , HPA022264: " "unprognostic (2.15e-2)" "unprognostic (1.13e-2)" "unprognostic (3.07e-2)" "unprognostic (9.00e-3)" "unprognostic (5.55e-2)" "unprognostic (2.02e-1)" "unprognostic (1.59e-1)" "unprognostic (1.78e-2)" "unprognostic (1.76e-1)" "unprognostic (1.72e-3)" "potential prognostic favorable (2.21e-4)" "unprognostic (6.02e-2)" "unprognostic (2.94e-3)" "validated prognostic unfavorable (4.93e-9)" "validated prognostic unfavorable (2.02e-5)" "validated prognostic unfavorable (7.09e-5)" "validated prognostic unfavorable (5.54e-4)" "potential prognostic favorable (7.25e-4)" "unprognostic (6.48e-2)" "unprognostic (1.84e-1)" "unprognostic (2.49e-1)" "unprognostic (1.54e-3)" "unprognostic (9.82e-2)" "unprognostic (3.25e-2)" "unprognostic (1.63e-1)" "unprognostic (1.49e-1)" "unprognostic (6.13e-2)" "unprognostic (4.24e-2)" "unprognostic (2.17e-1)" "unprognostic (3.59e-2)" "unprognostic (1.11e-1)" ZXDA ZNF896 ENSG00000198205 "Zinc finger X-linked duplicated A" P98168 X 57905430-57910458 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Epicardial cells: 11.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" HPA043789 Approved Approved Nucleoplasm NA NA "Cluster 63: Non-specific - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 7 Nucleoplasm "HPA043789: " "unprognostic (2.55e-2)" "unprognostic (2.76e-2)" "unprognostic (8.62e-2)" "unprognostic (8.53e-3)" "unprognostic (1.68e-1)" "unprognostic (3.02e-2)" "unprognostic (1.80e-1)" "unprognostic (8.11e-2)" "unprognostic (2.66e-1)" "unprognostic (2.44e-2)" "potential prognostic favorable (1.19e-8)" "unprognostic (5.73e-3)" "unprognostic (1.53e-1)" "unprognostic (9.94e-3)" "unprognostic (7.85e-3)" "unprognostic (2.13e-1)" "unprognostic (1.22e-1)" "unprognostic (6.16e-2)" "unprognostic (1.32e-1)" "unprognostic (5.94e-2)" "unprognostic (3.93e-3)" "unprognostic (7.95e-2)" "unprognostic (9.05e-2)" "unprognostic (3.28e-2)" "unprognostic (2.17e-1)" "unprognostic (2.40e-1)" "unprognostic (2.32e-1)" "unprognostic (5.53e-2)" ZXDB ZNF905 ENSG00000198455 "Zinc finger X-linked duplicated B" P98169 X 57592011-57597477 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 23.5;Endometrial luminal cells: 20.3;Epicardial cells: 27.3;Epididymal basal cells: 21.7;Ocular epithelial cells: 23.6;Suprabasal keratinocytes: 26.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" HPA043789 Approved Approved Nucleoplasm NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 16: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 26: Keratinocytes - Keratinization" 3 Nucleoplasm "HPA043789: " "unprognostic (1.81e-2)" "unprognostic (1.18e-1)" "unprognostic (8.47e-3)" "unprognostic (2.22e-1)" "unprognostic (2.55e-1)" "unprognostic (1.39e-2)" "unprognostic (3.67e-2)" "unprognostic (1.50e-2)" "unprognostic (1.82e-1)" "unprognostic (1.12e-1)" "potential prognostic favorable (6.71e-6)" "unprognostic (5.81e-2)" "unprognostic (3.37e-2)" "unprognostic (6.72e-2)" "unprognostic (1.21e-1)" "unprognostic (1.36e-1)" "unprognostic (2.51e-1)" "unprognostic (2.83e-1)" "unprognostic (1.32e-1)" "unprognostic (9.19e-2)" "unprognostic (2.05e-1)" "unprognostic (6.65e-2)" "unprognostic (1.96e-1)" "unprognostic (3.52e-2)" "unprognostic (7.42e-2)" "unprognostic (2.11e-1)" "unprognostic (2.72e-1)" "unprognostic (1.16e-1)" "unprognostic (2.90e-1)" "unprognostic (4.80e-3)" "unprognostic (3.47e-1)" ZXDC "FLJ13861, MGC11349" ENSG00000070476 "ZXD family zinc finger C" Q2QGD7 3 126437601-126475891 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 37.2" "Cell type enhanced" "Detected in many" "Myonuclei: 292.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 4.4" "Group enriched" "Detected in many" 4 "dendritic cells: 1.1;granulocytes: 1.7;monocytes: 4.4" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049593 Approved Nucleoli Yes No "Cluster 7: Non-specific - Innate immune response" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 63: Non-specific - Protein processing" "Cluster 55: Myocytes - Oxidative muscle function" 24 Nucleoli "HPA049593: " "unprognostic (4.05e-2)" "unprognostic (1.23e-1)" "unprognostic (2.18e-1)" "unprognostic (9.81e-2)" "unprognostic (1.21e-1)" "unprognostic (2.79e-2)" "unprognostic (1.17e-1)" "unprognostic (6.08e-2)" "unprognostic (2.40e-1)" "unprognostic (4.05e-2)" "potential prognostic favorable (1.12e-6)" "unprognostic (1.55e-2)" "unprognostic (3.69e-1)" "unprognostic (4.42e-3)" "unprognostic (3.47e-2)" "unprognostic (1.19e-1)" "unprognostic (2.48e-1)" "unprognostic (1.59e-3)" "unprognostic (1.27e-1)" "unprognostic (3.05e-2)" "unprognostic (3.56e-1)" "unprognostic (1.90e-1)" "unprognostic (1.16e-1)" "unprognostic (2.55e-1)" "unprognostic (1.96e-2)" "unprognostic (4.72e-3)" "unprognostic (1.19e-2)" "unprognostic (1.11e-1)" "unprognostic (2.32e-1)" "unprognostic (3.26e-2)" "unprognostic (1.26e-1)" ZYG11A ZYG11 ENSG00000203995 "Zyg-11 family member A, cell cycle regulator" Q6WRX3 1 52842511-52894998 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 2.7;testis: 3.5;thyroid gland: 2.2" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 37.2;Early primary spermatocytes: 22.2;Esophageal apical cells: 30.6;Plasma cells: 13.2;Prostatic glandular cells: 12.5;Proximal tubule cells: 108.0;Sertoli cells: 13.2;Undifferentiated spermatogonia: 30.0" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 6.0" "Cancer enriched" "Detected in many" 7 "Testicular Germ Cell Tumor (TCGA): 19.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Prostate - Prostate glandular cells, Testis - Spermatocytes, Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" "HPA030378, HPA030379" Uncertain Approved Nucleoplasm NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 48: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 88: Proximal tubular cells - Transmembrane transport" Nucleoplasm "HPA030378: , HPA030379: " "unprognostic (1.73e-2)" "unprognostic (1.46e-3)" "unprognostic (2.07e-1)" "unprognostic (4.55e-1)" "unprognostic (1.23e-1)" "unprognostic (7.63e-2)" "unprognostic (2.18e-1)" "unprognostic (3.86e-1)" "unprognostic (2.66e-1)" "unprognostic (2.89e-1)" "unprognostic (7.05e-2)" "unprognostic (2.47e-2)" ZYG11B "FLJ13456, ZYG11" ENSG00000162378 "Zyg-11 family member B, cell cycle regulator" Q9C0D3 1 52726453-52827336 "Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 73.8;tongue: 57.8" "Cell type enhanced" "Detected in many" "Myonuclei: 243.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028156 Uncertain Approved "Endoplasmic reticulum,Golgi apparatus,Vesicles" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 1: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 40 "Endoplasmic reticulum, Vesicles" "Golgi apparatus" "HPA028156: " "unprognostic (1.62e-2)" "unprognostic (4.72e-2)" "unprognostic (4.49e-2)" "unprognostic (2.18e-2)" "potential prognostic favorable (9.09e-4)" "unprognostic (1.35e-1)" "unprognostic (1.72e-1)" "unprognostic (3.45e-2)" "unprognostic (3.31e-3)" "unprognostic (2.29e-3)" "potential prognostic favorable (5.18e-8)" "unprognostic (1.44e-3)" "unprognostic (2.42e-2)" "unprognostic (2.54e-2)" "unprognostic (2.31e-1)" "unprognostic (1.38e-1)" "unprognostic (1.34e-1)" "unprognostic (1.98e-2)" "unprognostic (3.37e-1)" "unprognostic (1.10e-2)" "unprognostic (2.26e-3)" "unprognostic (1.72e-1)" "unprognostic (2.63e-1)" "unprognostic (4.56e-2)" "unprognostic (1.79e-2)" "unprognostic (3.35e-2)" "unprognostic (9.28e-2)" "unprognostic (3.13e-1)" "unprognostic (2.31e-1)" "unprognostic (4.91e-2)" "unprognostic (2.27e-1)" ZYX ENSG00000159840 Zyxin Q15942 7 143381295-143391111 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 23.8;Brain inhibitory neurons: 15.7;Breast myoepithelial cells: 14.6;Megakaryocytes: 37.1;Microglia: 12.7;Neutrophils: 19.1;Oligodendrocyte progenitor cells: 15.0;Other brain neurons: 12.8;Papillary tip epithelial cells: 14.0;Platelets: 23.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 163.9" "Group enriched" "Detected in all" 4 "dendritic cells: 58.5;granulocytes: 163.9;monocytes: 83.8" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Colon - Smooth muscle cells, Pituitary gland - Endothelial cells, Prostate - Smooth muscle cells, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004835, CAB009321, HPA073497, CAB075747" Enhanced Supported "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA 140000000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 74: Non-specific - Signal transduction" "Cluster 37: Neurons - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 102: Non-specific - Mixed function" 56 "Focal adhesion sites" "Plasma membrane, Actin filaments" "CAB009321: , CAB075747: , HPA004835: , HPA073497: " "unprognostic (5.58e-2)" "unprognostic (1.57e-2)" "unprognostic (5.83e-2)" "unprognostic (9.35e-3)" "unprognostic (3.30e-2)" "unprognostic (1.47e-1)" "unprognostic (6.02e-2)" "unprognostic (4.50e-2)" "unprognostic (1.31e-1)" "unprognostic (2.06e-1)" "unprognostic (3.20e-1)" "unprognostic (1.84e-2)" "unprognostic (1.19e-1)" "potential prognostic unfavorable (8.20e-5)" "unprognostic (2.02e-2)" "unprognostic (1.59e-2)" "unprognostic (3.35e-2)" "unprognostic (3.53e-3)" "unprognostic (1.49e-1)" "unprognostic (1.20e-1)" "unprognostic (1.34e-1)" "unprognostic (6.37e-2)" "unprognostic (2.35e-1)" "unprognostic (2.45e-1)" "unprognostic (3.01e-1)" "unprognostic (1.78e-2)" "unprognostic (2.07e-1)" "unprognostic (1.08e-1)" "unprognostic (1.63e-1)" "unprognostic (4.52e-1)" "unprognostic (4.84e-2)" ZZEF1 "FLJ10821, KIAA0399, ZZZ4" ENSG00000074755 "Zinc finger ZZ-type and EF-hand domain containing 1" O43149 17 4004445-4143030 "Predicted membrane proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 381.3;Neutrophils: 314.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031778, HPA031790" Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 49: Non-specific - Transcription" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 42: Non-specific - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 23 Nucleoplasm Mitochondria "HPA031778: , HPA031790: " "unprognostic (3.28e-2)" "unprognostic (3.78e-2)" "unprognostic (1.65e-2)" "unprognostic (2.35e-1)" "unprognostic (3.36e-2)" "unprognostic (5.27e-3)" "unprognostic (1.45e-1)" "unprognostic (3.02e-3)" "unprognostic (1.37e-3)" "unprognostic (1.17e-3)" "potential prognostic favorable (1.62e-5)" "unprognostic (1.05e-2)" "unprognostic (3.81e-3)" "unprognostic (2.24e-1)" "unprognostic (3.71e-2)" "unprognostic (1.08e-3)" "unprognostic (1.06e-1)" "unprognostic (1.41e-1)" "unprognostic (3.08e-1)" "unprognostic (2.14e-2)" "unprognostic (2.08e-1)" "unprognostic (3.99e-3)" "unprognostic (3.62e-2)" "unprognostic (1.31e-1)" "unprognostic (2.51e-2)" "unprognostic (4.03e-1)" "unprognostic (3.74e-1)" "unprognostic (6.74e-2)" "unprognostic (1.77e-1)" "unprognostic (4.56e-2)" "unprognostic (1.62e-1)" ZZZ3 "ATAC1, DKFZP564I052" ENSG00000036549 "Zinc finger ZZ-type containing 3" Q8IYH5 1 77562416-77683419 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053663, HPA054913, HPA066197" Uncertain Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim" No No "Cluster 3: Non-specific - Nuclear processes" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 7: Non-specific - Transcription" 24 "Nucleoplasm, Nucleoli, Nucleoli rim" "HPA053663: , HPA054913: , HPA066197: " "unprognostic (2.43e-1)" "unprognostic (9.97e-2)" "unprognostic (1.07e-1)" "unprognostic (1.90e-3)" "unprognostic (3.18e-2)" "unprognostic (1.11e-1)" "unprognostic (5.84e-2)" "unprognostic (2.22e-3)" "unprognostic (3.40e-2)" "unprognostic (7.21e-2)" "potential prognostic favorable (8.33e-8)" "unprognostic (5.25e-3)" "unprognostic (2.23e-1)" "unprognostic (7.84e-2)" "unprognostic (2.29e-1)" "unprognostic (1.09e-1)" "unprognostic (7.70e-2)" "unprognostic (6.87e-2)" "unprognostic (1.69e-1)" "unprognostic (3.35e-2)" "unprognostic (1.81e-2)" "unprognostic (3.02e-2)" "unprognostic (2.35e-2)" "unprognostic (1.06e-1)" "unprognostic (6.87e-3)" "unprognostic (1.06e-1)" "unprognostic (1.74e-1)" "unprognostic (1.63e-1)" "unprognostic (1.30e-1)" "unprognostic (1.03e-2)" "unprognostic (2.18e-1)"